[ { "cls_id": "homologset.agr.RGD:620300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DBM0-1", "uniprot_id": "ABCG8_MOUSE", "id": "Q9DBM0-1", "name": "ATP-binding cassette sub-family G member 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEKTKEETQLWNGTVLQDASQGLQDSLFSS-ESDNSLYFTYSG------------QSNTLEVRDLTYQ------------------------------VDIASQVPWFEQLAQFKIP------------------------------------------------WRSHSSQDSCELGIRNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKMK----SGQIWINGQPSTPQLVRKCVAHVRQHD--QLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVTTLSRLAKGN-RLVLISLHQPRSDIFRLFDLVLLMT-SGTPIYLGAAQQMVQYFTSIGHPCPRYSNPADFYVDLTSIDRRSKEREVATVEKAQSLAALFLEKVQGFDDFLWKAEAK---ELNTSTHTVSLTLTQDTDCG---TAVELPGMIEQFSTLIRRQISNDFRDLPTLLIHGSEACLMSLIIGFLYYGHGAKQ--LSFMDTAALLFMIGALIPFNVILDVVSKCHSERSMLYYELEDGLYTAGPYFFAKILGELPEHCAYVIIYAMPIYWLTNLRPVPE----LFLLHFLLVWLVVFCCRTMALAASAMLPTFHMSSFFCNALYNSFYLTAGFMIN------LDNLWIVPAWISKLSFLRWCFSGLMQIQFNGHLYTTQI------------------------GNFTFSILGDTMISAMDLNSHPLYAIYLIVIGISYGFLFLYYLSLKLIKQKSIQDW-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58428-3", "uniprot_id": "ABCG8_RAT", "id": "P58428-3", "name": "ATP-binding cassette sub-family G member 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEKTKEETQLWNGTVLQDASS-LQDSVFSS-ESDNSLYFTYSG------------QSNTLEVRDLTYQGGTCLRSWGQEDPHMSLGL--------SESVDMASQVPWFEQLAQFKLP------------------------------------------------WRSRGSQDSWDLGIRNLSFKVRSGQMLAIIGSAGCGRATLLDVITGRDHGGKMK----SGQIWINGQPSTPQLIQKCVAHVRQQD--QLLPNLTVRETLTFIAQMRLPKTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVRTLSRLAKGN-RLVLISLHQPRSDIFRLFDLVLLMT-SGTPIYLGVAQHMVQYFTSIGYPCPRYSNPADFYVDLTSIDRRSKEQEVATMEKARLLAALFLEKVQGFDDFLWKAEAK---SLDTGTYAVSQTLTQDTNCG---TAAELPGMIQQFTTLIRRQISNDFRDLPTLFIHGAEACLMSLIIGFLYYGHADKP--LSFMDMAALLFMIGALIPFNVILDVVSKCHSERSLLYYELEDGLYTAGPYFFAKVLGELPEHCAYVIIYGMPIYWLTNLRPGPE----LFLLHFMLLWLVVFCCRTMALAASAMLPTFHMSSFCCNALYNSFYLTAGFMIN------LNNLWIVPAWISKMSFLRWCFSGLMQIQFNGHIYTTQI------------------------GNLTFSVPGDAMVTAMDLNSHPLYAIYLIVIGISCGFLSLYYLSLKFIKQKSIQDW-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H221-1", "uniprot_id": "ABCG8_HUMAN", "id": "Q9H221-1", "name": "ATP-binding cassette sub-family G member 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGKAAEERGLPKGATPQDTSG-LQDRLFSS-ESDNSLYFTYSG------------QPNTLEVRDLNYQ------------------------------VDLASQVPWFEQLAQFKMP------------------------------------------------WTSPSCQNSCELGIQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIK----SGQIWINGQPSSPQLVRKCVAHVRQHN--QLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGN-RLVLISLHQPRSDIFRLFDLVLLMT-SGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDLTSIDRRSREQELATREKAQSLAALFLEKVRDLDDFLWKAETK---DLDEDTCVESSVTPLDTNCLP--SPTKMPGAVQQFTTLIRRQISNDFRDLPTLLIHGAEACLMSMTIGFLYFGHGSIQ--LSFMDTAALLFMIGALIPFNVILDVISKCYSERAMLYYELEDGLYTTGPYFFAKILGELPEHCAYIIIYGMPTYWLANLRPGLQ----PFLLHFLLVWLVVFCCRIMALAAAALLPTFHMASFFSNALYNSFYLAGGFMIN------LSSLWTVPAWISKVSFLRWCFEGLMKIQFSRRTYKMPL------------------------GNLTIAVSGDKILSVMELDSYPLYAIYLIVIGLSGGFMVLYYVSLRFIKQKPSQDW-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IGG8-1", "uniprot_id": "A0A0R4IGG8_DANRE", "id": "A0A0R4IGG8-1", "name": "ATP-binding cassette sub-family G member 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDDTVFHSGESFSSSYEKQIK-GRDILFSSPEEDSSLYFTYSG------------GRNELEVRNLNYE------------------------------VDTAAQIPWYEKLSEFKMP------------------------------------------------WEMHSNK---QTVIKDLNLHVHSGQMLAVIGSSGCGKTSLLDIITCRDEGGSMN----SGEILINGKPSTRSLVKKSIAHVRQDD--RLLPHLTVRETLAFVAKLRLPANFSQKQRDQRVDDVIAELRLRQCAHTRVGNEYVRGVSGGERRRVSIAVQLLWNPGILILDEPTSGLDSFTAHNLVITLYRLARGN-RLVLLSVHQPRSDIFQLFDLVVLLS-SGSAVYCGQAKDMVSYFTTLGYPCPRYCNPSDYYVDLISIDRRTPEKEAQCLEKASMLAAQFLEKVKNNEDFMWKSEVCGPPALEAPQSSVPSVSMKESVITVSKQKDQLPGKVHQFTTLIRRQVFNDYRDLVTLVVHGLEALLMSLLIGFLYFGCTEEG--LSIQDTVALLYMIGALTPFAVVLDVIAKCHSERAMLYHELEDGMYSVTPYFFAKVLGELPEHCAFTLVYGVPIYWLAGLNVAPD----RFLLNFLLVWLTVYCSRSMALFVAAALPTLQTSSFMGNALFTVFYLTAGFVIS------LENMWMVASWFSYISFMRWGFEGMLQVQFRGTRIPITI------------------------GNLTVEFDGIKVVEMMKMNQYPLFSCYLVLIAVSLVFILLYYLSLKFIKQKSSQDW-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08234-1", "uniprot_id": "YO075_YEAST", "id": "Q08234-1", "name": "Uncharacterized ABC transporter ATP-binding protein/permease YOL075C", "aln": "MSQQENGDVATELIENRLSFSRIPRISLHVRDLSIVASKTNTTLVNTFSMDLPSGSVMAVMGGSGSGKTTLLNVLASKISGGLTHNGSIRYVLEDTGSEPNETEPKRAHLDGQDHPIQKHVIMAYLPQQDVLSPRLTCRETLKFAADLKLNSSERTKKLMVEQLIEELGLKDCADTLVGDNSHRGLSGGEKRRLSIGTQMISNPSIMFLDEPTTGLDAYSAFLVIKTLKKLAKEDGRTFIMSIHQPRSDILFLLDQVCILSKGNVVYCDKMDNTIPYFESIGYHVPQLVNPADYFIDLSSVDSRSDKEEAATQSRLNSLIDHWHDYERTHLQLQAESYISNATEIQIQNMTTRLPFWKQVTVLTRRNFKLNFSDYVTLISTFAEPLIIGTVCGWIYYKPDKSSIGGLRTTTACLYASTILQCYLYLLFDTYRLCEQDIALYDRERAEGSVTPLAFIVARKISLFLSDDFAMTMIFVSITYFMFGLEADARKFFYQFAVVFLCQLSCSGLSMLSVAVSRDFSKASLVGNMTFTVLSMGCGFFVNAKVMPVYVRWIKYIAFTWYSFGTLMSSTFTNSYCTTDNLDECLGNQILEVYGFPRNWITVPAVVLLCWSVGYFVVGAIILYLHKIDITLQNEVKSKQKKIKKKSPTGMKPEIQLLDDVYHQKDLEAEKGKNIHITIKLEDIDLRVIFSAPFSNWKEGNFHHETKEILQSVNAIFKPGMINAIMGPSGSGKSSLLNLISGRLKSSVFAKFDTSGSIMFNDIQVSELMFKNVCSYVSQDDD-HLLAALTVKETLKYAAALRLHH-LTEAERMERTDNLIRSLGLKHCENNIIGNEFVKGISGGEKRRVTMGVQLLNDPPILLLDEPTSGLDSFTSATILEILEKLCREQGKTIIITIHQPRSELFKRFGNVLLLAKSGRTAFNGSPDEMIAYFTELGYNCPSFTNVADFFLDLISVNTQNEQNEISSRARVEKILSAWKANMDN--ESLSPTPIS-----EKQQYSQESFFTEYSEFVR-----KPANLVLAYIVNVKRQFTTTRRSFDSLMARIAQIPGLGVIFALFFAPVKHNY--TSISNRLGLAQESTALY-FVGMLGNLACYPTERDYFYEEYNDNVYGIAPFFLAYMTLELPLSALASVLYAVFTVLACGLPRTAG----NFFATVYCSFIVTCCGEALGIMTNTFFERPGFVVNCISIILSIGTQMSGLMSLGMSRVLKGFNYLNPVGYTSMIIINFAFPGNLKLTCE-DGGKNSD------------------------GTCEFANGHDVLVSYGLVRNTQKYLGIIVCVAIIYRLIAFFILKAKLEWIKW---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q0KI14-1", "uniprot_id": "Q0KI14_DROME", "id": "Q0KI14-1", "name": "ABC transporter domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELSNFSSGKKMSREERRYSVPHGPNTPLPPAASEDLHAWSIYRQNLNSDFTDSALGSSDKSPLPYGNFQLRDTTVQSILNHPRYGPKSPLGSN-------------MYTYLKFGLPRVFPPNAGSQRSHRPGPGPGAGPGHGHGGSSALGGVRGRVNRAFR----------------------------------DSSGAPAGAGSSGYDSSDNETTRSRVPPNLRKYRSESDFR------------AIGGMPHSRPESRAQIGGGGVPMAALRQANSRASIAVGQHHHQMQQHQQQYGKHYGHRSHSEADLLGAGLSQVDGGGGGMG--YDYNEARLYGSSRQ-----------------------------YGNGNGHNPGSRKQSGMGLIYP-----------------------------------------------NIQVHCLDVNPCLRGVSMQAKAGDLFAIMATSQREGSALAECLAGLTER-------LGGEILINGQQVSRRGLRELCSYVPALEVSSLDPRMSVQCTLNFHAALRGPIDRSDL--EERMDVLIEDLGLNTVRASNVS-----TLTHSEKQRLSVACQLLAQSSLLILDQVTSNMDIFDTFFLVEYLRQWCSGG-RIVIMTLQPPTFEILSMCSGVLLLS-GGRTVFSGSRADLPRHMGELGYPCPPFKNPADYYLDLVTLDDLSAAAMLESSARIESLANAWDQINSEP-------------PLAAPPASLPNFTMKAGFFG------QISALIKRFAGYKQ------PGSLLTWISKLIAAAVLSLFIGCIFWDVPASDPQLSYHDRLGYHHCVMVLVYWPLVMLTIRDTQEDRRHAERDIRLGLYTRSLYIIVQSLLGLFPSLCIWLAYLLPAHSMAGLYTYSNSSDTGIYLYMGYMLLYLTLIQTLALFCAHLLPCKVSASIVNGLISLAVAAVGGYLVHP------QNLAQFWSWLQFVSPERWLLPVLVQDEYSAETLSNSAGLQLCRNKQVQHQEIIVQQPCPPPNGTQVLVDFELLPQQHVLDPTPTYDQTTSVALVLGSVLVFCVTFIVFLCNCRGACRRKRSR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . : : : .: . : . .: . ::.:. :.* : *::..: ::* : :: . .*.* :*. : .:: ::* : * . ::*: ** : * :* :: :* : :* .* *. . :. :: .*::*:::. *** :. :*:**: **.:* * : :: * : . : :::::: * ::: . *:*:: .* . : * .: :: :*: ** : * :*:::** ::: . : : : : . : : : .: : . : :.: :. :: * : . .* : :: : :* : . .:* :::. * : * : .* : . : . :.: : . : .* : : .: : :: . . : : : : .: : : ", "identical_positions": 50, "similar_positions": 181, "identity": "3.71%" }, { "cls_id": "homologset.agr.RGD:620301", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WU06-1", "uniprot_id": "AVIL_RAT", "id": "Q9WU06-1", "name": "Advillin", "aln": "--------------------------------------------------------MSLSSAFRTVTNDPG-IITWRIEKMELVLVPLSAHGNFYEGDCYIILSTR---------------RVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKRGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVE-MSWDSFNQGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMTVLQNTLGRRSIIKPAVP--DEVTDQQQKSTIMLYHVSDTTGQLSVTEVATRPLVQELLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTG--LGKTFSIGKIAKIFQDKFDVTLLHTKPEVAAQERMVDDG--------NGKVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVN---------GKPCYILYIWQGRHASQDELAASAYQAVEVDQQFGGAPVQVRVSMGKEPRHFMAIFKGKLVIYEG---GTSRKGNVEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLWTQAEH--YLWYGKGSSG-DERAMAKELAELLCDGDADTVAEGQEPPEFWD----------LLGGKAPYANDKRLQQE-------------------------------TLDIQVRLFECSNKTG-RFLVTEVTDFTQDDLSPGDVMLLDTWDQVFLWIGAEANATEKEGALSTAQEYLVTHPSGRDPDTP-ILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELG-DATAIVRITTDMKNATLSLNSSESGPKYYPVEVLLKSQDQELPEDVDPTKKENYLSERDFVSVFGITRGQFVSLPGWKQLQLKKEAGLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88398-1", "uniprot_id": "AVIL_MOUSE", "id": "O88398-1", "name": "Advillin", "aln": "--------------------------------------------------------MSLSSAFRAVSNDPR-IITWRIEKMELALVPLSAHGNFYEGDCYIVLSTR---------------RVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVE-MSWDSFNRGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPGLMTVLQDTLGRRSMIKPAVS--DEIMDQQQKSSIMLYHVSDTAGQLSVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTG--LGKIFSTGKIAKIFQDKFDVSLLHTKPEVAAQERMVDDG--------KGQVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVN---------GKPHYILYIWQGRHASRDELAASAYRAVEVDQQFDGAPVQVRVSMGKEPRHFMAIFKGKLVIYEG---GTSRKGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLRTQAEH--YLWYGKGSSG-DERAMAKELVDLLCDGNADTVAEGQEPPEFWD----------LLGGKTAYANDKRLQQE-------------------------------TLDVQVRLFECSNKTG-RFLVTEVTDFTQEDLSPGDVMLLDTWDQVFLWIGAEANATEKKGALSTAQEYLVTHPSGRDPDTP-ILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELG-DATAIVRITADMKNATLYLNPSDGEPKYYPVEVLLKGQNQELPEDVDPAKKENYLSEQDFVSVFGITRGQFTALPGWKQLQLKKERGLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75366-1", "uniprot_id": "AVIL_HUMAN", "id": "O75366-1", "name": "Advillin", "aln": "--------------------------------------------------------MPLTSAFRAVDNDPG-IIVWRIEKMELALVPVSAHGNFYEGDCYVILSTR---------------RVASLLSQDIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVE-MSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAKIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVP--DEIIDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMG--LGKTFSIGKIAKVFQDKFDVTLLHTKPEVAAQERMVDDG--------NGKVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVN---------GKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEG---GTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEH--YLWYGKGSSG-DERAMAKELASLLCDGSENTVAEGQEPAEFWD----------LLGGKTPYANDKRLQQE-------------------------------ILDVQSRLFECSNKTG-QFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALATAQQYLHTHPSGRDPDTP-ILIIKQGFEPPIFTGWFLAWDPNIWSAGKTYEQLKEELG-DAAAIMRITADMKNATLSLNSNDSEPKYYPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGWKQLQMKKEKGLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07171-1", "uniprot_id": "GELS_DROME", "id": "Q07171-1", "name": "Gelsolin", "aln": "MDASGAATMAVLSSLLVFLALSSSLCSAGTLNARPAFPVQSGEIQPSGQNSKQAARRVMHPSFANAGRTPG-LEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIEN-------------KKDKKLSWDVHFWLGLETSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVETNAQGETRLFQVKGKRNVRVRQVN-LSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQIRDQDHNGRARVQIVDDFSTDADKQHFFDVLGSGSADQVPDESTADEDSAFERTDAAAVSLYKVSDASGKLKVDIIGQKPLTQAMLDTRECFILD-TGSGIFVWVGKGATQKEKTDAMAKAQEFLRTKKYPAWTQIHRIVEGSESAPFKQYFDTWRDAGMSHSRLIRSALGIGSDELLNDDEIDSVVTQLKKSGGRAFGFMPDHGQNVIETITQYVAKPGSDEIVVSTVPFDEKLPLLGFASYVLTYNYEANN--------GDTGSLTYVWHGVKAS----AAARKRAFEEGLVGSKDGLLVQTNQGHEPRHFYKIFKGKLLTSFT---ALP--------VTAQLFRIRGTVESDVHASEVAADSSSLASSDAFVLHSGKSHKIYIWNGLGASAFEKQAAVDRFSDYWDDVELEQVEEGAEPDEFWE----------ELNGEGQYDR-SLGDDG-------------------------------APLLESRLFHCHLSSGGFLKVEEVAQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEENGKLLDTAKLYFNLEPTARSFDTVSIIRVPQGKEPRVFKRMFPNWDDNYWQNQPSYEDMKQLVI-DANNEV-----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q23989-1", "uniprot_id": "QUAI_DROME", "id": "Q23989-1", "name": "Villin-like protein quail", "aln": "-------------------------------------MELSLSPKETEIRPNTIPDLKVDATFRKVAKHAITFAIWKIDEDRLEAVQRSHYGTFYDSCAYIIYAASLSGHYANHETITREQKPNVSLERYIHYWLGKNVSEQNRSNVVHKIQELDSYLGNISSIYRETQNLESARFLSYFKKGYDVRSGALIS--------APQRPRLFQLYARKWLRSIEVATIDWSHFNSDYVMVLQTDNLTYVWIGRSSSGIERRSALDWVQKHCS----GSPITIVDDGYEQAMSQEHKELWNTMLPLKKRMVCQASQLVSEYADYNSNKFRIYKCNQRGRLHLDQLDVGMPAKDDLSDAHGVYLLDNYGQSIWLWVGGQAPQADALSAMGNGRAFVKKKKYPDNTLVVRVLEGHEPVEFKRLFANWLNVWQENT-------RGHKPVSTKFGKLDAHSLCERPKMAADTQLVDDG--------RGERVIYRVFGDQVQEVPISKTVVFTTNASFVVKYSVQCATVVPADLASVGIKTIIYQWNGSEASVESISRADKFAKASFDGLKEPGMFVQLYEFDEPPHFLQIFEGKLIIRRGQRTEMPYNGNSNALLDTFLLKVYGDASYNAKAVEETHLSS-ISSKDCYVIKTNHVW---VWCGQSSTG-DAREMAKAVGALMGENS--LVLEGKESKEFWQSVAMYFNQTLVINGNGNSCSSSTSSSSGAGSMCNGSSNGGNISPTLSNNCYLNTSVPSKPRPPVQLFLVWWQQS-SLRYEEILGFDQQDLSSDCTYILDTGSLTYVWLGSQAPNQER--YTAIAQSYVQNAPFGRRSATA-LAVVRQFQEPNVFKGFFESWQNDYGKNFHSYEKMRKDLGNKVTSNCCFASEGSALILNNRQKDFDGHKKYPLTVLIQEMDMLPPDINPLKREVHLTHDDFVSVFNMSFYEFDELPKWKKMELKKQFKLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:* . . . : *:*:: . : :*.** . .::: : : *. :*:*:* : * :: . .. :**. *.. . :**.* ** * .***.* ..*.: : : **::: .:: :: :* :. . :* . ::*: . : * .:. *: .*: .:. . * . : :. . . . .. . : . :*: .: * : : : ::** * *::* * *.: : **.:. *:: * ** * : : :* *.. **: * .* . .::* : . . :: * : * . : .::: *. : : * *:* .** : : * : *: ** ** **:***: . . *::: * . :.:* * . :* : *.* ::: : :* * .::. : : .. . : . * ** *. ***: :.*: . .. :** . . : *: : *:**.. :**: . ::*:* . *. *: *. * .* * : : * ** *. * *: . . :**.::: : .. ", "identical_positions": 117, "similar_positions": 211, "identity": "12.15%" }, { "cls_id": "homologset.agr.RGD:620302", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZG1-1", "uniprot_id": "S22AN_RAT", "id": "Q9QZG1-1", "name": "Solute carrier family 22 member 23", "aln": "MAIDRRREAAGSGAGRQPAPAEENGSLPPGDAAASAPLGGRAGSGGSAEIQPLPALHPSGGPHSSCCAAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWCHGAGKGTELAGATVTGRWGDMGNWTSPSATPFST--ASWGTTSNRSNSS-----DTPPLPSPPGKGNNDSNCECHAWDYGIRTGLVQNVVSKWDLVCDNAWKVHVAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSVIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFIITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLILYLTQKNCVSPESDIKGVMPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVK--VPLLENFYADYYTMASIALASCLAMCLVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESR---DQNLPENIANGEHYTRQPLLSHKK-GEQPLLLTNAELKDYS-----GLHDVAAVGDGLSEGATANGMKTM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHH2-1", "uniprot_id": "S22AN_MOUSE", "id": "Q3UHH2-1", "name": "Solute carrier family 22 member 23", "aln": "MAIDRRREAAGSGAGRQPAPAEENGSLPPGDAAASAPLGGRAGSGSSAEIQPLPALHPSGGPHSSCCAATAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPDFWCRGAGKGTELAGATVTGRWGDMGNWTSPSATPFST--ASWGTTSNRSNSS-----DTPPLPSPPGKGNNDSNCDCHAWDYGIRTGLIQNVVSKWDLVCDNTWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSTIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFIITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLILYLTQKNCVSPESDIKGVMPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVK--VPLLENFYADYYTMASIALASCLAMCLVVKFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESR---NQNLPENIANGEHYTRQPLLPHKK-GEQPLLLTNAELKDYS-----GLHDVAAVGDGLPEGATANGMKTM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1A5C7-1", "uniprot_id": "S22AN_HUMAN", "id": "A1A5C7-1", "name": "Solute carrier family 22 member 23", "aln": "MAIDRRREAAGGGPGRQPAPAEENGSLPPGDAAASAPLGGRAGPGGGAEIQPLPPLHPGGGPHPSCCSAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVLLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELAGVTTTGRGGDMGNWTSLPTTPFAT--APWEAAGNRSNSSGADGGDTPPLPSPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVK--VPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDS--------GMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESR---DQNLPENISNGEHYTRQPLLPHKK-GEQPLLLTNAELKDYS-----GLHDAAAAGDTLPEGATANGMKAM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PAI9-1", "uniprot_id": "A0A8M1PAI9_DANRE", "id": "A0A8M1PAI9-1", "name": "", "aln": "-------------------MCETVMAVSQLDTESHAPENG--------FVTPETSKSPG----------------LLSQTDGGVLPSVGGFG-KYQKQLIVLTWIPAIFIGFSQFSDNFLLTNP---CPEPHN--------------NSSQLLTVAPTAVST--VFTGVN-----------------------TEAASQCNCTPSSYKLQNGLEQNIVTKWNLVCDSAWKIHIAKFSLLVGSIFGYLVLGVLADWFGRHPVLILSVVFLLVFGMTVAFSVNLPMFGTLRFFEGFCLAGITLSLYVLRIELCLPGWRFSITMVANFMMLAGQLLMPGLAALCRDWQILQAVIVCPLLLMLSYIWAFPESLRWLLATQQYSRSKWIMERISKKNNINLQEDAEELMTELNGALQKQPKKTCIVKMVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMEKKTVGFVEKLHDFYAEYYVMAVIAVASCVFLCPAVALMGRRGGLLMFMIITALASLLQLGLLNLLGKYGDHLSL--------VHSDELNDKFSVAFSIIGMFSSHAVSNLSIFFCAEITPSVIRGGGLGLVLASAGFGMLTSPIMELHNQKGYFLHHIIFACCTLICIICILLLPETR---NQPLPETLSDGESYTRQPLLPPRKPGEQRLLLTKSESREYARVGDTPLHEAAATVVSTMDSTASSAVDIHMLIDAPIQQEPAQVQLLSMETLTSSQGQDELKQSVEEHPKSVLGTIPNTSTPLAVNSIPKSKRPESPPHDVLAVLSSAVEDASLIIHPVPTGLPSILDSVVPPAAVGSPLEVGNEVDSIESKRPESPPDDVLAVLSSPIEDTSLTIHPVPSELPSTLDTVIPATVGSPLEVNNEEDSTDSVSPPIDLPLCALTQSNNPSSIGQSPNLLNDIPPSSSIDSHTHPVSEILPPSPTELSMLDPSSQMNAAPPIDSGTPLLQLDAPPELNSIESAPPSLSNGSTSLLAAHATSTDSDSVTESGNPLMVNSTVSSPIDSGLPSDVDIPNTANGGTSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDS2-1", "uniprot_id": "Q9VDS2_DROME", "id": "Q9VDS2-1", "name": "", "aln": "----------------MKKDNLYRGWMPNIRRNSPAPLDLGHMAHSFTCTDPKANEVSPQTPHPKANN-------LADDNDDDVITHIMGNFGPWQLRSLLILFLCKIPAAW--FMACILFTAPDLYPEEEYK----------------CDTTAFGPDVNST--VSLDHCYVMVNYG----------------ESAYAMRQCRKFLYTTG---FHSLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLHCGLRCLAAVSCCFMITSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQLEELRER--MLEPMPAVHWMHLWMGQRRSTFHLVAVHMALATFMVVNTGL--LLHVRSFGREHLVSNTLAMG-------LAEMLGCFLALHLTFNLSERKWQWAGGFAIVVG---------------------------------------CIGSICWFLAEEDMPEVYG-LTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSCLSFSAVTWARVWQLSAS--FLTLLRQVSPALSLSAFCLLVILG-GLGTCCLVTRD------------KEQPPVGAVVNKGQQLIAFT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDR9-1", "uniprot_id": "Q9VDR9_DROME", "id": "Q9VDR9-1", "name": "Solute carrier family 22 member 3", "aln": "--------------------------MTDSQSMGSIPR--------------------------------------KSSPELDVVEQVNGSFGRWQLRTILLIFLCKIPSAW--FTAIIIYTAPYPWKGELVCHPADWNVSRSQTEHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQSSLPCEHVEHRTDYKSLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSGKARIIVVTLSELFWSMGLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEAALRQLLESATYNNRKVPLTLDVQLTMYANDLDQ--------KSKQKHSYCQVWDGETK-RSQLVYIHLIWGGAMVLYNII--LLMIRNLGAQQVHVNTAAMG-------FAEMVGLFVGLYLILYTR-RHWRWAGNLMIIAGLSTYLIWLLP-----ETERNSRRVGLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSVISFSRVCLLFCPFLSCLTVIHHLVPITILATMGWIYGLALRRLNRYYWNTEQPQISQVPTPNTYRRQSAIILRRCSTVSSDCSAYSNELLSNFERNMAVSIADIWHINFHPSSEIEMEVEQSGPEAHRAHSSETI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . * . : .*: : * :* ::: :: : .: * :: * : : . . .. : :.: :::*:* : :: .* ::* : .. : : . :. . .: :. :* : .. . : : : :: *. : . . * .*:*.:: .*. : : .::::: .:: ** : : : . *.. : : :* . *: : :..: : *: . ::* .* : : .: : * . : * . : ::: : .. :: : :. : . . . . . . ", "identical_positions": 26, "similar_positions": 133, "identity": "2.5%" }, { "cls_id": "homologset.agr.RGD:620304", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54853-1", "uniprot_id": "KCNH6_RAT", "id": "O54853-1", "name": "Voltage-gated inwardly rectifying potassium channel KCNH6", "aln": "MPVRRGHVAPQNTYLDTIIRKFEGQSRKFLIANAQMENCAIIYCNDGFCELFGYSRVEVMQRPCTCDFLTGPNTPSSAVSRLAQALLGAEECKVDILYYRKDASSFRCLVDVVPVKNEDGAVIMFILNFEDLAQLLAKSSSRSLTQRLLSHSFLGSEGSHSRPSGQGPGPGRGKYRTVSQIPQFTLNFVEFNLEKHRSGSTTEIEIIAPHKVVERTQNVTEKVTQVLSLGADVLPEYKLQAPRIHRGTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLSDQDESQRGTCGYTCSPLTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHPRRIAVHYFKGWFLIDMVAAIPFDLLIFRTGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNVERPYLEPKIGWLDSLGAQLGKQYNGSDPASGPSVQDKYVTALYFTFSSLTSVGFGNVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLHRALLQHCPAFRGASKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEILRDDVVVAILGKNDIFGEPASLHARPGKSSADVRALTYCDLHKIHRADLLEVLDMYPAFADTFWNKLEVTFNLRDADGGLQSTPRQAPGHQDPQGFFLNDSQSGAAPSLSISDTSALWPELLQQMPP--SPPNPRQDLDCWHRELGFKLEQLQAQMNRLESRVSSDLSRILQLLQH--PQGRPSYILGASASSDLASFPETSVTRSSESTLLVGHVPSAQTLSYGDLDDHIQTPRNFSPRTPHVAMAMDKTLVPSSEQEQPGGLLSPLASPLRPLEVPGLG-GSRFPSLPEHLSSVPKQLEFQRHGSDPGFTRS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H252-4", "uniprot_id": "KCNH6_HUMAN", "id": "Q9H252-4", "name": "Voltage-gated inwardly rectifying potassium channel KCNH6", "aln": "MPVRRGHVAPQNTYLDTIIRKFEGQSRKFLIANAQMENCAIIYCNDGFCELFGYSRVEVMQQPCTCDFLTGPNTPSSAVSRLAQALLGAEECKVDILYYRKDASSFRCLVDVVPVKNEDGAVIMFILNFEDLAQLLAKCSSRSLSQRLLSQSFLGSEGSHGRPGGPGPGTGRGKYRTISQIPQFTLNFVEFNLEKHRSSSTTEIEIIAPHKVVERTQNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLSDQDESRRGACSYTCSPLTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHPRRIAVHYFKGWFLIDMVAAIPFDLLIFRTGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNVERPYLEHKIGWLDSLGVQLGKRYNGSDPASGPSVQDKYVTALYFTFSSLTSVGFGNVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLHRALLQHCPAFSGAGKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEILRDDVVVAILGKNDIFGEPVSLHAQPGKSSADVRALTYCDLHKIQRADLLEVLDMYPAFAESFWSKLEVTFNLRDAAGGLHSSPRQAPGSQDHQGFFLSDNQSDAAPPLSISDASGLWPELLQEMPPRHSPQSPQEDPDCWPLKLGSRLEQLQAQMNRLESRVSSDLSRILQLLQKPMPQGHASYILEAPASNDLALVPIASETTSPGPRLPQGFLPPAQTPSYGDLDDCSPKHRNSSPRMPHLAVATDKTLAPSSEQEQPEGLWPPLASPLHPLEVQGLICGPCFSSLPEHLGSVPKQLDFQRHGSDPGFAGSWGH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************************:****************************************************************************.*****:*****:*********.**.* ***.*******:********************.*********************************************** *****************************************:**:*.***************************************************************************************************************************************** *********.****:**************************************************************************************************************************************************** **.*************************************************************.****:*******************:***************::**.*********** ***:*:****** ** *****.*.**.***.*****:*.*******:*** ** .*::* *** :** :***************************: ***:.**** *.**.*** .* :* * *. . * *.:*.*** ******* . ** *** **:*:* ****.******** ** .******:**** ** *. *.******.******:**********: * ", "identical_positions": 857, "similar_positions": 58, "identity": "89.46%" }, { "cls_id": "homologset.agr.RGD:620305", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VD75-1", "uniprot_id": "HIP1_MOUSE", "id": "Q8VD75-1", "name": "Huntingtin-interacting protein 1", "aln": "MDRMASSMKQVSNPLPKVLSRRGVGAGMEAAERESFERTQTVSVNKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSNAMLCWKFCHVFHKLLRDGHPNVLKDSLRYKNELSDMSRMWGHLSEGYGQLCSIYLKLLRTRMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTTAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADT----LQGHRDRFMEQFTKLKDLFQRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEVSSPDSEPVLEKDDLMDMDASQQTLFDNKFDDVFGSSLSSDPFNFNNQNGVNKDEKDHLIERLYREISGLTGQLDNMKIESQRAMLQLKGRVSELEAELAEQQHLGRQAMDDCEFLRTELDELKRQREDTEKAQRSLTEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSVARQAQVDLEREKKELADSFAR--------TQEQQDVLENLKHELATSRQELQVLHSNLETSAQSEAKWLTQIAELEKEQGSLATVAAQREEELSALRDQLESTQIKLAGAQESMCQQVKDQRKTLLAGIRKAAEREIQEALSQLEEP-TLISCAGSTDHLLSKVSSVSSCLEQLEKNGSQYLAC---PEDISELLHSITLLAHLTGDTIIQGSATSLRAPP-EPADSLTEACRQYGRETLAYLSSLEEEGTMENADVTALRNCLSRVKTLGEELLPRGLDIKQEELGDLVDKEMAATSAAIEAATTRIEEILSKSRAGDTGVKLEVNERILGSCTSLMQAIKVLVVASKDLQKEIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATIMVDAADLVVQGKGK----FEELMVCSREIAASTAQLVAASKVKANKGSLNLTQLQQASRGVNQATAAVVASTISGKSQIEETDS--MDFSSMTLTQIKRQEMDSQVRVLELENDLQKERQKLGELRKKHYELAGVAEGWEEGTEASPSTVQEAIPDKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GA90-1", "uniprot_id": "A0A8I6GA90_RAT", "id": "A0A8I6GA90-1", "name": "Huntingtin-interacting protein 1", "aln": "MDRMASSMKQVPNPLPKVLSRRGVGAGMEAAERESFERTQTVSVNKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSNAMLCWKFCHVFHKLLRDGHPNVLKDSLRYKNELSDMSRMWGHLSEGYGQLCSIYLKLLRTRMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTTAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADT----LQGHRDRFMEQFTKLKDLFQRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEVSSPDSEPVLEKDDLMDMDASQQSLFDNKFDDIFGSSLSSDPFNFNNQNGVNKDEKDHLIERLYREISGLTGQLDNVKIESQRAMLQLKGRVSELEAELAEQQHLGRQATDDCEFLRTELDELKRQREDTEKAQRSLTEIEKKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSVARQAQVDLEREKKELADSFARVSEQTQRKTQEQQDVLETLKHELATSRQELQVLHGNLETSAQSEAKWLTQIAELEKEQGSLATAAAQREEEFSALRDQLESTQLKLAGAQDSMCQQIKDQRRILLAGARKAAELEIQEALGQLEEPALLISCAGATDHLLSKVNSVSSCLEQLEKSRSQYLAC---PEEISELLHSITLLGHLTSDTIIQGTATSLRAPP-ESADSLTEACRQYGRETLAYLSSLEEEGAMEKADTTAIANCLGKIKTIGEELLPRGLDIKQEELGDLVDKEMAATSAAIEAATTRIEEILSKSRAGDTGVKLEVNERILGSCTSLMQAIKVLVVASKDLQKEIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATIMVDAADLVVQGKGK----FEELMVCSHEIAASTAQLVAASKVKANKGSLNLTQLQQASRGVNQATAAVVASTISGKSQIEETDS--MDFSSMTLTQIKRQEMDSQVRVLELENDLQKERQKLGELRKKHYELAGVAEGWEEGTEASPSAVQEAVPDKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00291-1", "uniprot_id": "HIP1_HUMAN", "id": "O00291-1", "name": "Huntingtin-interacting protein 1", "aln": "MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADT----LQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLASTEESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEP-PLISCAGSADHLLSTVTSISSCIEQLEKSWSQYLAC---PEDISGLLHSITLLAHLTSDAIAHGATTCLRAPP-EPADSLTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELGDLVDKEMAATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGK----FEELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDN--MDFSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEEGTEASPPTLQEVVTEKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33338-1", "uniprot_id": "SLA2_YEAST", "id": "P33338-1", "name": "Protein SLA2", "aln": "-------MSRIDSDLQKALK-------------------------KACSVEETAPKRKHVRACIVYTWDHQSSKAVFTTLKTLPLANDEVQLFKMLIVLHKIIQEGHPSALAEAIRDRDWIRSLGRVHSGGSS-YSKLIREYVRYLVLKLDFHAHHRGFNNGTFEYEEYVSLVSVSDPDEGYETILDLMSLQDSLDEFSQIIFASIQSER-----RNTECKISALIPLIAESYGIYKFITSMLRAMHRQLNDAEGDAALQPLKERYELQHARLFEFYADCSSVKYLTTLVTIPKLPVDAPDVFLINDVDESKEIKFKKREPSVTPARTPARTPTPTPPVVAEP--AISPRPVSQRTTSTPTGYLQTMPTGATTGMMIPTATGAANAIFPQATAQMQPDFWANQQAQFANEQNRLEQERVQQLQQQQAQQELFQQQLQKAQQDMMNMQLQQQNQHQNDLIALTNQYEKDQALLQQYDQRVQQLES---EITTMDSTASKQLANKDEQLTALQDQLDVWERKYES-----------LAKLYSQLRQEHLNLLPRFKKLQLKVNSAQESIQKKEQLEHKLKQKDLQMAELVKDRDRARLELERSINNAEADSAAATAAAETMTQDKMNPILDAILESGINTIQESVYNLDSPLSWSGPLTPPTFLLSLLESTSENATEFATSFNNLIVDGLAHGDQTEVIHCVSDFSTSMATLVTNSKAYAVTTLPQEQSDQILTLVKRCAREAQYFFEDLMSENLNQVGDEEKTDIVINANVDMQEKLQELSLAIEP--LLNIQSVKSNKETNPHSELVATADKIVKSS----EHLRVDVPKPLLSLALMIIDAVVALVKAAIQCQNEIATTT--SIPLNQFYLKNSRWTEGLISAAKAVAGATNVLITTASKLITSEDNENTSPEQFIVASKEVAASTIQLVAASRVKTSIHSKAQDKLEHCSKDVTDACRSLGNHVMGMIEDDHSTSQQQQPLDFTSEHTLKTAEMEQQVEILKLEQSLSNARKRLGEIRRHAYYNQDDD----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:: . * *.*. ** ..:*.* *.**.*:**: * ..:.:::.::.:: ***:.: : :*: *:**::::***..* :::* :: : .:.*: . *. *.:* *:: * ::::*::: * .. :. :. .. ** :: :: ::::. :. :: * :* *:: .* :*:::.** :* :. :*.: ..:* :* * ** ::*: *.::* ::: .*.::*:. *: **:** :.*:.: . :.* . . :* *. : *. :. : . :* .:. :: .... :. ..*:: .*:. : : . * * **: :* : :: ::: * :. * :: :: *..* : .: : :: .: .:: .:* . :: :: .:**:: : . *: : . . .: . *::* . .:: *: .:::: :* : :*::: .:. . .*:. *. .::.:: . *.: : :*: . :* . ::. **::: :*:.* . .. .*** : * *. :: .. .: :. : : ::*.:: :. . : :. : .: : * * :*.: :: .**: :: .* .*. : .* :. : *:* .* *: * :: . : : . . .: ::::..* ::::* : :*. . :::*: .*: *: : *.**. : : . ::** ************:***. .:.::: :*. :: ...: *:::*.*:*:**** ******:**:. * :*::.*:.*.:* .: .:. .: ..*.. :. : :* **:.**.:*:**:.*.: *::***:*:: * . ", "identical_positions": 179, "similar_positions": 409, "identity": "17.02%" }, { "cls_id": "homologset.agr.RGD:620306", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7ESP2-1", "uniprot_id": "F7ESP2_RAT", "id": "F7ESP2-1", "name": "", "aln": "MGKSGLGKTWRRNPGKAAIISIWEK--VDLEKIGGETLGRLLIVYPWTQRFFDKFGNLSSALAIMGNPRIRAHGKKVLTSLGSAVENMDN------LKETFAHLSELHCDKLHVDPQNFKLLGNMLVIVLSTHFAKEFTPEVQAAWQKLVMGVANALSHKYH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04444-1", "uniprot_id": "HBBZ_MOUSE", "id": "P04444-1", "name": "Hemoglobin subunit beta-H1", "aln": "-------MVHFTAEEKAAITSIWDK--VDLEKVGGETLGRLLIVYPWTQRFFDKFGNLSSALAIMGNPRIRAHGKKVLTSLGLGVKNMDN------LKETFAHLSELHCDKLHVDPENFKLLGNMLVIVLSTHFAKEFTPEVQAAWQKLVIGVANALSHKYH------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P69892-1", "uniprot_id": "HBG2_HUMAN", "id": "P69892-1", "name": "Hemoglobin subunit gamma-2", "aln": "-------MGHFTEEDKATITSLWGK--VNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKHLDD------LKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVASALSSRYH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P69891-1", "uniprot_id": "HBG1_HUMAN", "id": "P69891-1", "name": "Hemoglobin subunit gamma-1", "aln": "-------MGHFTEEDKATITSLWGK--VNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDATKHLDD------LKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTAVASALSSRYH------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZM12-1", "uniprot_id": "Q6ZM12_DANRE", "id": "Q6ZM12-1", "name": "", "aln": "-------MVQWSDSERKTIASVWSK--INVDEIGPQTLARVLVVYPWTQRYFGAFGDLSCASAIMGNPKVSEHGKTVLKALEKAVKNVDD------IKTTYAKLSQLHCEKLNVDPDNFKLLADCLSIVIATNFGPAFNPSVQSTWQKLLSVVVAALTSRYF------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF15-1", "uniprot_id": "Q9VF15_DROME", "id": "Q9VF15-1", "name": "", "aln": "----------MNSDEVQLIKKTWEIPVATPTDSGAAILTQFFNRFPSNLEKFP-FRDVP-LEELSGNARFRAHAGRIIRVFDESIQVLGQDGDLEKLDEIWTKIAVSHIPR-TVSKESYNQLKGVILDVLTAACS--LDESQAATWAKLVDHVYGIIFKAIDDDGNAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * . * * :.: :* . . * * ::. : **.:. *. :: : . : :.: :. ::::: * : *. :.:: * . : *:: . : . ::* *:: * : ", "identical_positions": 17, "similar_positions": 49, "identity": "10.12%" }, { "cls_id": "homologset.agr.RGD:620307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55173-1", "uniprot_id": "PDPK1_RAT", "id": "O55173-1", "name": "3-phosphoinositide-dependent protein kinase 1", "aln": "---------------------------------------------------------MARTTSQLYDAVPIQSSVVLCSCPSPSMVRSQTEPSSSPGIPS-------------------------------------GVSRQGSTMDGTTAEARPSTN---------------------PLQQHP-----------------------AQLPPQPRKKR-----------------------PEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPDS---------KQARAN------------------------------------------------------SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEG-YGPLKAHPFFESITWEN--LHQQTPPKLTAYLPAMSEDD--EDCYG------------------------------------------------------------------NYDNLLSQFGCMQVSSSSSSHSLSAVDASLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNL----------------------------------------------------------------------------------------------ILKMGPVDKRKGLFA-------------------------------------------------------------------------------------------------------------------------------RRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKN----------------FKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQQYQ-----------------SSPDAAVQ----------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2A0-1", "uniprot_id": "PDPK1_MOUSE", "id": "Q9Z2A0-1", "name": "3-phosphoinositide-dependent protein kinase 1", "aln": "---------------------------------------------------------MARTTSQLYDAVPIQSSVVLCSCPSPSMVRSQTEPGSSPGIPS-------------------------------------GVSRQGSTMDGTTAEARPSTN---------------------PLQQHP-----------------------AQLPPQPRKKR-----------------------PEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---------KQARAN------------------------------------------------------SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYHFPEKFFPKARDLVEKLLVLDATKRLGCEEMEG-YGPLKAHPFFETITWEN--LHQQTPPKLTAYLPAMSEDD--EDCYG------------------------------------------------------------------NYDNLLSQFGFMQVSSSSSSHSLSTVETSLPQRSGSNIEQYIHDLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNL----------------------------------------------------------------------------------------------ILKMGPVDKRKGLFA-------------------------------------------------------------------------------------------------------------------------------RRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKN----------------FKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQQYQ-----------------SNPDAAVQ----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15530-1", "uniprot_id": "PDPK1_HUMAN", "id": "O15530-1", "name": "3-phosphoinositide-dependent protein kinase 1", "aln": "---------------------------------------------------------MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIP--------------------------------------GGSRQGPAMDGTAAEPRPGAG---------------------SLQH-------------------------AQPPPQPRKKR-----------------------PEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPES---------KQARAN------------------------------------------------------SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEG-YGPLKAHPFFESVTWEN--LHQQTPPKLTAYLPAMSEDD--EDCYG------------------------------------------------------------------NYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNL----------------------------------------------------------------------------------------------ILKMGPVDKRKGLFA-------------------------------------------------------------------------------------------------------------------------------RRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKN----------------FKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQ-----------------SHPDAAVQ----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6A1A2-1", "uniprot_id": "PDPK2_HUMAN", "id": "Q6A1A2-1", "name": "Putative 3-phosphoinositide-dependent protein kinase 2", "aln": "------------------------------------------------------------------------------------MVRTQTESSTPPGIP--------------------------------------GGSRQGPAMDGTAAEPRPGAG---------------------SLQH-------------------------AQPPPQPRKKR-----------------------PEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD-HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMYIQITDFGTAKVLSPES---------KQARAN------------------------------------------------------SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEG-YGPLKAHPFFESVTWEN--LHQQTPPKLTAYLPAMSEDD--EDCYG------------------------------------------------------------------NVS----------------------------------------------------------------------WPGWRAR------------------------------------------------------------------------------------------------QVALGPP--CTGLHA-------------------------------------------------------------------------------------------------------------------------------RAP-------------DPR-------VICSRKGR--------------------------VSVPLR------------------QACWWL--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W0V1-4", "uniprot_id": "PDPK1_DROME", "id": "Q9W0V1-4", "name": "3-phosphoinositide-dependent protein kinase 1", "aln": "MKCKSWSNKINNYVVRKIKSIKINGTQQQLQLPGSGASGIAAAAVITVASDCGENCSSNGTEHQQHFNIATTTATSATEATMPAMAKEKASATVSLGESNFRDINLKDLAVVVEAASRLHHQQNVCGCGAVSSTENNNNSRYGSSKYLTNGHTSPLAAAVASNSSSVATTPHCRMLHNCSLQQYQNDIRQQTEILDMLRQQHQQGYQSQQQQQQPQQQQEQQQQQEQSQQQQQLQNPAPRRSPNDFIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIKREREVMHQMTNVPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYINRVGSFDVACTRHYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTAHERALATEHCSEQRRSNSDEDDEDSDRLENEDEDFYDRDSEELDDGDDEQQQEEMDSPRHRQRRYNRHRKASFVGTAQYVSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVDFPQGFDKDAEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFFAGIDWQT--LRQQTPPPIYPYLPGVSQDEDFRSSYT------------------------------------------------------------------VPGDLEPGLDERQISRLLSAELGVGSSVAMPVKRST---------AKNSFDLN-----DAEKLQRLEQQKTDKWHVFADGEV----------------------------------------------------------------------------------------------ILKKGFVNKRKGLFA-------------------------------------------------------------------------------------------------------------------------------RKRMLLLTTGPRLIYIDPVQMIKKGEIPWSPDLRAEYKN----------------FKIFFVHTPNRTYYLDDPEGYAIHWSEAIENMRKLAYG-----------------DPSSTSAVSCSSGSSNSLAVISNSSAASSSNSPTVKRSSPVNAP----------QASTASDNRTLGSTRTGTSPSKKTASK---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12236-1", "uniprot_id": "PKH2_YEAST", "id": "Q12236-1", "name": "Serine/threonine-protein kinase PKH2", "aln": "----------------MYFDKDNSMSPRPLLPSDEQKLNINLLTKKEKFSHLDPHYDAKATPQRSTSNRNVGDLLLEKRTAKPMIQKALTNTDNFIEMYHNQQRKNLDDDTIKEVMINDENGKTVASTNDGRYDNDYDNNDINDQKTLDNIAGSPHMEKNR---------------NKVKIEHDSSSQKP-----------------IAKESS-KAQKNIIKKG------------------IKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLLN--PTNNSVSKPEYDLSTRSK----------------------------------------------------SFVGTAEYVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLIIRDLVKKILVKNLDRRLT-------ISQIKEHHFFKDLNFKDGSVWSKTPPEIKPYKINAKSMQAMPSGSDRKLVKKSVNTLGKSHLVTQRSASSPSVEETTHSTLYNNNTHASTESEISIKKRPTDERTAQILENARKGINNRKNQPGKRTPSGAASAALAASAALTKKTMQSYPTSSSKSSRSSSPATTSRPGTYKRTSSTESKPFAKSPPLSASVLSSKVPMPPYTPPMSPPMTPYDTYQMTPPYTTKQQDYSDTAIAAPKPCISKQNVKNSTDSPLMNKQDIQWSFYLKNINEHVLRTEKLDFVTTNYDILEKKMLKLNGSLLDPQLFGKPRHTFLSQVARSGGEVTGFRNDPTMTAYSKTEDTYYSKNIIDLQLLEDDYRIEGGDLSELLTNRSGEGYKCNQNSSPMKDDDKSESNNKGSSVFSGKIKKLFHPTSAAETLSSSDEKTKYYKRTIVMTSFGRFLVFAKRRQPNPVTNLKYELEYDINLRQQGTKIKELIIPLEMGTNHIVVIQTPYKSFLLSTDKKTTSKLFTVLKKILNSNTNKIEKELLQRNQKVIERRTSSSGRAIPKDLPTSKSPSPKPRTHSQSPSISKHNSFSESINSAKSNRSSRIFETFINAKEQNSKKHAAPVPLTSKLVNGLPKRQVTVGLGLNTGTNFKNSSAKSKRS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03407-1", "uniprot_id": "PKH1_YEAST", "id": "Q03407-1", "name": "Serine/threonine-protein kinase PKH1", "aln": "------------------------MGNRSLTEADHALLSKPLVPTSAEHTQTQEYP----RPFVDGSNSQSGSELQASPQGQ-FGEKALTSTNRFIPLAN-------------------------------------DDPGMQHEMGLD-----PSMRRRR---------------EEWAERGAAKIVKD-----------------VVDPATGELTKHVVKMG------------------IKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSK----------------------------------------------------SFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGFPQIVKDLVKKLLVRDPNDRLT-------IKQIKAHLFFHEVNFEDGSVWDDNPPEIQPYKINAEAMKPLQKVSESDTTVKMAN-----------------------------------------------------LQLAGNGHADTPLQAPAATSQEHSVISMTAATAAFNKDYTSQPKLGSKSSTSVRSASNNTDREVIQKKVSKNRASVSSPSISTTSR------------------------------------------------GKDNRSRSSD--------AFWSRYLQNMDERVLLMKEVALSTRN---LEDSPVGLENVALD------------------------YKN-------------------------------------------------------PLDIEPPTDSAG------------------------------KFYKKMFLITNLGRALVFVKRRSLSMWEEQEFELQFELELND--------VEKIRFISDQVLEIDGSRTIFIGCKERAVLMKLWKLIHNGMTAKP------------KVVS--PKSDHKMFDKFILQKRQNTKK---KNQAPPVPQSNRLINGLPDR----------CILKTPEEGALHTKRPTSLQTRSSSNYSK-------LLARSTQMRKNMTRTDEK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.. . * . . :. :** ** :*:*::* * ** : :.** *: .*. ::::.* *:. *: .: :: ...* ****: .*** : ** :*::* :.: **:: :*:*.*::::: * : :* .::***:*******: :* ::***:**:: : :. ******:*****:* : .*:**:***::*::** ***:. *:*: *::::. *. * .***.*:* : ** :: * ** : :: : ...** : .* . . . . : : . . . : . . ", "identical_positions": 95, "similar_positions": 117, "identity": "7.86%" }, { "cls_id": "homologset.agr.RGD:620308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30935-1", "uniprot_id": "SSR3_MOUSE", "id": "P30935-1", "name": "Somatostatin receptor type 3", "aln": "-----------------------------------------------------MATVTYPSSEPTTLDPGNASSTWPLDTTLGNTSAGASLTGLAVSG-----------------------------------------------ILISLVYLVVCVVGLLGNSLVIYVVLRHTSSPSVTSVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPR---GMSTCHMQWPEPAAAWR-TAFIIYTAALGFFGPLLVICLCYLLIVVKVRSTTRRVRAPSCQWVQAPACQRRRRSERRVTRMVVAVVALFVLCWMPFYLLNIVNVVCPLP--EEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRILLRPSRRIRSQEPGSG-----------PPEKTEEEEDEEEEERREEEERRMQRGQEMNGRLSQIAQAGTSGQQPRPCTGTAKEQQLLPQEATAGDKASTL--SHL---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30936-1", "uniprot_id": "SSR3_RAT", "id": "P30936-1", "name": "Somatostatin receptor type 3", "aln": "-----------------------------------------------------MAAVTYPSSVPTTLDPGNASSAWPLDTSLGNASAGTSLAGLAVSG-----------------------------------------------ILISLVYLVVCVVGLLGNSLVIYVVLRHTSSPSVTSVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARMVSAAVWVASAVVVLPVVVFSGVPR---GMSTCHMQWPEPAAAWR-TAFIIYTAALGFFGPLLVICLCYLLIVVKVRSTTRRVRAPSCQWVQAPACQRRRRSERRVTRMVVAVVALFVLCWMPFYLLNIVNVVCPLP--EEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRILLRPSRRVRSQEPGSG-----------PPEKTEEEEDEEEEERREEEERRMQRGQEMNGRLSQIAQPGPSGQQQRPCTGTAKEQQLLPQEATAGDKASTL--SHL---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32745-1", "uniprot_id": "SSR3_HUMAN", "id": "P32745-1", "name": "Somatostatin receptor type 3", "aln": "------------------------------------------------------MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSG-----------------------------------------------VLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPR---GMSTCHMQWPEPAAAWR-AGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAP--------SCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLP--EEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVG-----------PPEKTEEEDEEEEDG---EESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0S0WMT8-1", "uniprot_id": "A0A0S0WMT8_DROME", "id": "A0A0S0WMT8-1", "name": "", "aln": "MEGGWWRGGGGGGRLGGKAIMEGHSTPNGAAASHRNNSTRTNIATNGCAHSGILLFVLTAMTLTSLITPTEQLAVAPNGTTLHQLESVESESYPSINGTQNETMVTSVRPHLDHRNRPTQQNGSHYLEYDDDGPDCSYSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFLLYTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVSCNIEWPDTQNSHTDSTFILYSLVLGFATPLTFILVFYCLVIRKLHTVGPKHKSK-----------EKKRSHRKVTKLVLTVISAYIFCWLPHWISQVALISSAPQRCASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTCAARKDVNAQLQLENSFFPKFGKGRQSERLLGGNGKGGAQRGALTKKKCLATRNNNAPMATTTTTTTTTTGTDAVTCLQPPVHQVPAEIQVGNPATVLVVNAETNNCKPPVLHTDLXDRAPSMPLETVVFIARRXDHQVELDLDTAIDCQAIARQPECLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .: * : :. * .::* : .: * : ::.* :: ::* :**::**:**:******:*.: :**.:******:*** *::*:*** :. ****. **: *. .*..*** : * :**.***:** ** *.*:**. *:: *** .*::*.:::***::*:.. : * :*:::**:. : : **:*: .*** ** .* : * *:: *:::. : : .::**.*:**::*::*:: :::**:*.:: ::. : .. . :.::: .*.*:**. *****.*** .**:.* : .:*: . : .*: : : .:. :: *. :: : . .: . : :* * .*: ::.: . ", "identical_positions": 117, "similar_positions": 158, "identity": "19.37%" }, { "cls_id": "homologset.agr.RGD:620309", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08163-1", "uniprot_id": "CAP1_RAT", "id": "Q08163-1", "name": "Adenylyl cyclase-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADMQNLVERLERAVGRLEAVS--------HTSDMHCGYGD----------------SPSK-GAVPYVQAFDSLLANPVAEYLKMSKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQP--AGNKLSDLLAPISEQIQEVITFREKNRGSKFFNHLSAVSESIQALGWVALAAKPGPFVKEMNDAAMFYTNRVLKEYRDVDKKHVDWVRAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGL---------PSGPSVGSGPPPPPPGPPPPP-------VPTSSGSDDSAS--RSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKPATKKEPALLELEGKKWRVENQENVSNLVIDDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSRDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPT-EGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40124-1", "uniprot_id": "CAP1_MOUSE", "id": "P40124-1", "name": "Adenylyl cyclase-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADMQNLVERLERAVGRLEAVS--------HTSDMHCGYGD----------------SPSK-GAVPYVQAFDSLLANPVAEYLKMSKEIGGDVQKHAEMVHTGLKLERALLATASQCQQP--AGNKLSDLLAPISEQIQEVITFREKNRGSKFFNHLSAVSESIQALGWVALAAKPGPFVKEMNDAAMFYTNRVLKEYRDVDKKHVDWVRAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGL---------PSGPSVGSGPPPPPPGPPPPP-------ISTSSGSDDSAS--RSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKPATKKEPALLELEGKKWRVENQENVSNLVIDDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSRDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPT-EGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01518-1", "uniprot_id": "CAP1_HUMAN", "id": "Q01518-1", "name": "Adenylyl cyclase-associated protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADMQNLVERLERAVGRLEAVS--------HTSDMHRGYAD----------------SPSKAGAAPYVQAFDSLLAGPVAEYLKISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQP--AENKLSDLLAPISEQIKEVITFREKNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKKHVDWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGL---------PSGPSAGSCPPPPPPCPPPPP-------VSTISCSYESAS--RSSLFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPT-EGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPX6-1", "uniprot_id": "Q9VPX6_DROME", "id": "Q9VPX6-1", "name": "Adenylyl cyclase-associated protein", "aln": "MFSCCRSNPKAGKKEKEKRNAEEENGGQVTEKEEPQLNGKPGTPKEEPEPVKPEKELLEAHNPEDVPTSTQPNTAQPTQAEAASKSSPANPALAPKEPEPLARSTHSSTSTAPPASMTSGDAEEADEVVVVATVTPTTPPPQPPPTKSCLSRHNSTHQSIKKKVNISNRAEIIEPDPLPLLLLASQNQGSLLDDDEVFSDSLPPPKRESMCAPYIEGDVVSETLFFAHGLPSWFDDERLNDIGCIEPPVTPVGRDELELKRQRLYTELLRAAHAAVEHSVAVRDNEPEAKPSAAVDHLESICERLETLVDRLERTLTAPQPIELPTPTLPPPPAEEEEALPVFEKAETPPPPPSPPSSNMSVAGFEDIVAGPLSQYLTLSAKIGGDVAQHAELVKSAFGSQLQYVTLATQIAQP--AQPKQAELLKPTSTQISAIQDFREKHRSSPFFNHLSAISESIPALGWVCVEKTPGPYVKEMNDAGQFYTNRVLKEWKEKDVTHVEWARAWVQTLTELQAYIRQYHTTGLVWSGKG-------------------AAPAGGAPPPPPPGGLPPPPP-----MLDLSALKLDSAGDDRSALFAQINQGADITKGLKKVTGDMQTHKNPSLRTGPAPFKS-PAQSGGSKAVAAPS---AAQAKAPVFERDGKKWIIEYQKNNTGLLVENAEMNNVVYVFKCEGSTLTVKGKVNNIVFDSCKKCSLLFDSVVASVEFVNCQSVQMQVLGSVPTVSIDKTDGCQMYLSKDSLGVEIVNSKSSEMNILLPD-DSGDYTELALPEQYKTTIAGKTLKTVCVDSLG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17555-1", "uniprot_id": "CAP_YEAST", "id": "P17555-1", "name": "Adenylyl cyclase-associated protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDSKYTMQGYNLVKLLKRLEEATAR------------LEDVTIYQEGYIQNKLEASKNNKPSDS------GADANTTNEPSAEN---------------APEVEQDPKCITAFQSYIGENIDPLVELSGKIDTVVLDALQLLKGGFQSQLTFLRAAVRSRKPDYSSQTFADSLRPINENIIKLGQLKESNRQSKYFAYLSALSEGAPLFSWVAVD-TPVSMVTDFKDAAQFWTNRILKEYRESDPNAVEWVKKFLASFDNLKAYIKEYHTTGVSWKKDGMDFADAMAQSTKNTGATSSPSPASATAAPAPPPPPPAPPASVFEISNDTPATSSDANKGGIGAVFAELNQGENITKGLKKVDKSQQTHKNPELRQSSTVSSTGSKSGPPPRPKKPST---LKTKRPPRKELVGNKWFIENYENETESLVIDANKDESIFIGKCSQVLVQIKGKVNAISLSETESCSVVLDSSISGMDVIKSNKFGIQVNHSLPQISIDKSDGGNIYLSKESLNTEIYTSCSTAINVNLPIGEDDDYVEFPIPEQMKHSFADGKFKSAVFEHAG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : ::** .. : .: .*. : .*:. :. : : :* :*. * . :::: .: : : * : :* : . :: * * . :* : ::*.:* * * :***:**. :.**.: .* . *.:::**. *:***:***::: * . *:*.: :: :*:***:::****: *. * ..*: .: .*.** *.** : . :: .::**::*** .**:.**:* . :***** *: . : . .:. ..: ... * *:** :* :* : :: ::: .: :: ** : :***:* * ... :. .:::*. :. ::.::.... :** .:* :**:*:** : ****:**. ** .: *: :*: :* :..*: *:.:*** * . .: :. : *", "identical_positions": 110, "similar_positions": 178, "identity": "13.51%" }, { "cls_id": "homologset.agr.RGD:62031", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LLE4-1", "uniprot_id": "A0ABK0LLE4_RAT", "id": "A0ABK0LLE4-1", "name": "", "aln": "MSKMAASETVRVRLQFDYPPPATPHCTVFWLLVDLNRCRVVTDLISLIRQRFGFSSGALLGLYLEGGLLPPSESARLVRDNDCLRVKLEDQGLPEALIVSNGGDSNFPCRKSKKRAFKLVEDEETDQGYKYPDKYWKRQEDSGPNEKASDLETKLFPDEVRRTKNKRKSKVAGIPAEEDEEETKKKSSKRKEKCEQKKQTRASKSPKQQTHKEGGSQNCSFPRASYRSSLAKARRRS--STGAKGSPSYLSESESCPDSVSDGHCSVTTMQGVTLSEKLSAELLKDG-ATKTAAANRQSSKPSFTFSSGKGKASRASSSSSDSSSESEDQFLVSKNMLEGASD-FLKTTGLFAGQGCSSPGLSLETPGIMGWKPSDSNRGRQAPGP--NVPVPTSLGRGWGRGEDFLFGKGLRGRGIRGRGRGRGQTVSCILNRSSESQKQKQLNDILTNSSTVIQVSERLLFVSWPPFPHASYLSPVVWCGVGPPFLTSNEDTCLLQNPVETSKKDYSLLPLLAAAPQVGEKIAFKLLELTSDYSPDVSDYKEGKILSHDPETQQVDIEVLSSLPALKEPGKFDLVYHNENGTEVVEYAVTQEKRITVFWKELIDPRLIIDSSSSISSK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SU73-1", "uniprot_id": "COIL_MOUSE", "id": "Q5SU73-1", "name": "Coilin", "aln": "---MAASETVRLRLQFDYPPPATPHCTVFWLLVDLNRCRVVTDLISLIRQRFGFSSGALLGLYLEGGLLPPAESARLVRDNDSLRVKLEDQGLPENLIVSNGGDSSFPCRKAKKRAFKLMEDEETDQGYKSLKKHCKRQEDSGQNEKASDLETKLLPDETGRTKSKKKSKVTGSPAEEDEEETKKKSSKRKEKCEPKKQTRASKSSKQQTPKEGASQNCSFPRASPRS-LGKARRRS--STGLKGSSGHLSESESCPESVSDGHCSV-MMQEVTFSEKLSAELLKDAPATKTAAANRQASKPGFTFSSGKGKASRTSSSSSDSSSESEDQFLVSKNMLEGASAGFLKPTGLFAGQGGSGPGLSLETPGIMGWKSSDSNRGRQAPGPP-STPVPTSLGRGWGRGEDLLFGKGLRGRGVRGRGRGRGQAVSCVFNRSSESQKQRQLNDILTNSSVVIQN------------------------------------------PVEPPKKDYSLLPLLAAAPQVGEKIAFKLLELTSDYSPDVSDYKEGKILSHDPETQQVDIEVLSSLPALKEPGKFDLVYHNENGTEVVEYAVTQEKRITVLWRELIDPRLIIDSSGSISST---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38432-1", "uniprot_id": "COIL_HUMAN", "id": "P38432-1", "name": "Coilin", "aln": "---MAASETVRLRLQFDYPPPATPHCTAFWLLVDLNRCRVVTDLISLIRQRFGFSSGAFLGLYLEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKV-TLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAG-FLKTVGLFAGRGRPGPGLSSQTAGAAGWRRSGSNGGGQAPGASPSVSLPASLGRGWGREENLFSWKGAKGRGMRGRGRGRGHPVSCVVNRSTDNQRQQQLNDVVKNSSTIIQN------------------------------------------PVETPKKDYSLLPLLAAAPQVGEKIAFKLLELTSSYSPDVSDYKEGRILSHNPETQQVDIEILSSLPALREPGKFDLVYHNENGAEVVEYAVTQESKITVFWKELIDPRLIIESPSNTSSTEPA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ********:***************.******************************:************:**********.******::*:.* :* ..** .:. **:*****:* *.***: . * .*: * :*:.. ***. ***.* ..*:. .*.*:*.*.: .. :*:**:*:**.*:***** **::: .**.* *: *: ..*.** *:.* *. * **:*:. *. * *.. ****** :*:*** ..* :: . ****.:** *: :**.::*:: : * .*:::..***:* ::*******:**:** *:*.. * *: ***..*****:* ..**** :*.* **: *.** * ****. ...:*:******** *::: ** :***:********:.***:.***::.*:*:****::.***.:** ***..*****************************.***********:****:*********:*******:**************:**********.:***:*:*********:*... **. ", "identical_positions": 356, "similar_positions": 148, "identity": "57.14%" }, { "cls_id": "homologset.agr.RGD:620310", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CYT6-1", "uniprot_id": "CAP2_MOUSE", "id": "Q9CYT6-1", "name": "Adenylyl cyclase-associated protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDMAGLMERLERAVIRLEQLSAGLD--------GPPRG--CGEVNGVN-GGVAP------------SVEAFDKLINSMVAEFLKNSRVLAGDVETHAEMVHGAFQAQRAFLLMVSQYQQP--QENEVAVLLKPISEKIQEIQTFRERNRGSNMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVRSYLNIWSELQAYIREHHTTGLTWSK----------TGPVASTASAFSILSSGPGLPPPPPPPPPPGPPPPFENEDKKEEPSPSR----SALFAQLNQGEAITKGLRHVTDDKKTYKNPSLRAQG-QIRSPTKTHTPSPTSPKSNSPQKHTPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLVFDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSEDALDCEIVSAKSSEMNVLVPQD--DDYREFPIPEQFKTIWDGSKLVTEPAEIMA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52481-1", "uniprot_id": "CAP2_RAT", "id": "P52481-1", "name": "Adenylyl cyclase-associated protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADMLGLMQRLEFAVSRLERLSSGLH--------EPPGG--CGEVNSLSRGIVAP------------SVEAFDKLINSMVAEFLKNSRVLAGDVETHAEMVHGAFQAQRAFLLMVSQHQQP--QENEVAVLLKPISEKIQEIQTFRERNRGSDMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLRDYKHSDLRHVDWVRSYLKIWSELQAYIKEHHTTGLTWSK----------TGPVASTASAFSILSSGPGLPPPPPPPPPPGPPPPFENEGGKEEPSPSR----SALFAQLNQGEAITKGLRHVTDDKKIYKNPSLRAQG-QIRSPTKTRTPSPTSSKSNSPQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLVFDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSKDALDCEIVSAKSSEMNVLVPQG--DDYREFPIPEQFKTIWDGSKLITEPAEIMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40123-1", "uniprot_id": "CAP2_HUMAN", "id": "P40123-1", "name": "Adenylyl cyclase-associated protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANMQGLVERLERAVSRLESLSAESH--------RPPGN--CGEVNGVI-AGVAP------------SVEAFDKLMDSMVAEFLKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQP--HENDVAALLKPISEKIQEIQTFRERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSK----------TGPVASTVSAFSVLSSGPGLPPPPPPLPPPGPPPLFENEGKKEESSPSR----SALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCEKSTIQIKGKVNSIIIDNCKKLGLVFDNVVGIVEVINSQDIQIQVMGRVPTISINKTEGCHIYLSEDALDCEIVSAKSSEMNILIPQD--GDYREFPIPEQFKTAWDGSKLITEPAEIMA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IXA9-1", "uniprot_id": "A0A0R4IXA9_DANRE", "id": "A0A0R4IXA9-1", "name": "Adenylyl cyclase-associated protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEALVGRLERAVVRLEAVAVKLQ--------SCPGGLINGDISAVINGGESQ------------SMEAFDRLLSGSVSEYVQSSAAIGGDVAKHAEMVNNALQVQRTLLKMAMTHQEP--AKTELADLLRPLSDQIQAVQNFREKNRGSSLFNHLSAVSESIPALGWVAVCQKPGPYVKEMNDAAMFYTNRVLKDFKDTDARHVEWVRSYLSIWTDLQTFIREHHCTGLIWSK----------TGPKAPPS-----LLSAPLLPPPPPPPPPMMIDS---CSSPADASSVQH----AALFAQLNQGEEITKGLKHVCDEQKTHKNPNLRSQSGKTHHDSPSKTQSSSS--SNPARKHPPVLELEGKKWRVEYQDQCAELLIEDTELRQVVYVFSCSGSTLQVKGKVNSIIVDNCKKLGLVFDNVVGIVEIINSRDIQLQVMGKVPTISINKTEGCHVYLSKDSLDCEIVSAKSSEMNILVPEGE-DDYREFPVPEQFKTVWDGSSLVTEPTKIAG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPX6-1", "uniprot_id": "Q9VPX6_DROME", "id": "Q9VPX6-1", "name": "Adenylyl cyclase-associated protein", "aln": "MFSCCRSNPKAGKKEKEKRNAEEENGGQVTEKEEPQLNGKPGTPKEEPEPVKPEKELLEAHNPEDVPTSTQPNTAQPTQAEAASKSSPANPALAPKEPEPLARSTHSSTSTAPPASMTSGDAEEADEVVVVATVTPTTPPPQPPPTKSCLSRHNSTHQSIKKKVNISNRAEIIEPDPLPLLLLASQNQGSLLDDDEVFSDSLPPPKRESMCAPYIEGDVVSETLFFAHGLPSWFDDERLNDIGCIEPPVTPVGRDELELKRQRLYTELLRAAHAAVEHSVAVRDNEPEAKPSAAVDHLESICERLETLVDRLERTLTAPQPIELPTPTLPPPPAEEEEALPVFEKAETPPP-PPSPPSSNMSVAGFEDIVAGPLSQYLTLSAKIGGDVAQHAELVKSAFGSQLQYVTLATQIAQP--AQPKQAELLKPTSTQISAIQDFREKHRSSPFFNHLSAISESIPALGWVCVEKTPGPYVKEMNDAGQFYTNRVLKEWKEKDVTHVEWARAWVQTLTELQAYIRQYHTTGLVWSG----------KGAAPAGG--------AP--PPPPPGGLPPPPPMLDLSALKLDSAGDDR----SALFAQINQGADITKGLKKVTGDMQTHKNPSLRTGPAPFKSPAQSGG-SKAVAAPSAAQAKAPVFERDGKKWIIEYQKNNTGLLVENAEMNNVVYVFKCEGSTLTVKGKVNNIVFDSCKKCSLLFDSVVASVEFVNCQSVQMQVLGSVPTVSIDKTDGCQMYLSKDSLGVEIVNSKSSEMNILLPDDS-GDYTELALPEQYKTTIAGKTLKTVCVDSLG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17555-1", "uniprot_id": "CAP_YEAST", "id": "P17555-1", "name": "Adenylyl cyclase-associated protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDSKYTMQGYNLVKLLKRLEEATARLEDVTIYQEGYIQNKLEASKNNKPSDSGADANTTNEPSAENAPEVEQDPKCITAFQSYIGENIDPLVELSGKIDTVVLDALQLLKGGFQSQLTFLRAAVRSRKPDYSSQTFADSLRPINENIIKLGQLKESNRQSKYFAYLSALSEGAPLFSWVAVD-TPVSMVTDFKDAAQFWTNRILKEYRESDPNAVEWVKKFLASFDNLKAYIKEYHTTGVSWKKDGMDFADAMAQSTKNTGATSSPSPASATAAPAPPPPPPAPPASVFEISNDTPATSSDANKGGIGAVFAELNQGENITKGLKKVDKSQQTHKNPELRQSSTVSSTGSKSGPPPRPKKPSTLKTKRPPRKELVGNKWFIENYENETESLVIDANKDESIFIGKCSQVLVQIKGKVNAISLSETESCSVVLDSSISGMDVIKSNKFGIQVNHSLPQISIDKSDGGNIYLSKESLNTEIYTSCSTAINVNLPIGEDDDYVEFPIPEQMKHSFADGKFKSAVFEHAG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *** . *** . . . .: .*: : : : * : * ::::..: * : . :* . * *:* . :* : ::* :* * * :***:**. . :.*:.* .* . *.:::**. *:***:*::::..* *:*.: :: :*:::*:::* **: *. .. . .. *.*** . .. . .*:**::*** *****::* . : :***.** : : . . . :.* * *:** :* .: :: ::: : :: .*. : :***** * ... :. .:::* :. ::.::.... :** :* :**:*::* ::***:::*. ** .: *: :*: :* . .** *:.:*** * . .: : . .", "identical_positions": 102, "similar_positions": 161, "identity": "12.56%" }, { "cls_id": "homologset.agr.RGD:620311", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07747-1", "uniprot_id": "AAD4_YEAST", "id": "Q07747-1", "name": "Probable aryl-alcohol dehydrogenase AAD4", "aln": "----------------------------------------------MGSMNKEQAFELLDAFYEAGGNCIDTANSYQNEESEIWIGEWMKSRKLRDQIVIATKFTGDYKKYEVGGGKSAN-YCGN--HKHSLHVSVRDSLRKLQTDWIDILYVHWWDYMSSIEEVMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKTPFSIYQGKWNVLNRDFERDIIPMARHFGMALAPWDVMGGGRFQSKKAMEERKKNGEGLRTVSGTSKQTDKEVKISEALAKVAEEHGTESVTAIAIAYVRSKAKNVFPLVGGRKIEHLKQNIEALSIKLTPEQIEYLESII--PFDVGFPTNFIGDDPAVTKKASLLTAMSAQISFD-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42884-1", "uniprot_id": "AAD14_YEAST", "id": "P42884-1", "name": "Putative aryl-alcohol dehydrogenase AAD14", "aln": "MTDLFKPLPEPPTELGRLRVLSKTAGIRVSPLILGGASIGDAWSGFMGSMNKEQAFELLDAFYEAGGNCIDTANSYQNEESEIWIGEWMASRKLRDQIVIATKFTGDYKKYEVGGGKSAN-YCGN--HKRSLHVSVRDSLRKLQTDWIDILYIHWWDYMSSIEEVMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKTPFSVYQGKWNVLNRDFERDIIPMARHFGMALAPWDVMGGGRFQSKKAMEERKKNGEGLRTFVGGPEQTELEVKISEALTKIAEEHGTESVTAIAIAYVRSKAKNVFPLIGGRKIEHLKQNIEALSIKLTPEQIEYLESIV--PFDVGFPKSLIGDDPAVTKKLSPLTSMSARIAFDN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47182-1", "uniprot_id": "AAD10_YEAST", "id": "P47182-1", "name": "Putative aryl-alcohol dehydrogenase AAD10", "aln": "----------------------------------------------------------------------------------------MASRKLRDQIVIATKFTTDYKGYDVGKGKSAN-FCGN--HKRSLHVSVRDSLRKLQTDWIDILYVHWWDYMSSIEEVMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKTPFSIYQGKWNVLNRDFERDIIPMARHFGMALAPWDVMGGGRFQSKKAVEERKKKGEGLRTFFGTSEQTDMEVKISEALLKVAEEHGTESVTAIAIAYVRSKAKHVFPLVGGRKIEHLKQNIEALSIKLTPEQIKYLESIV--PFDVGFPTNFIGDDPAVTKKPSFLTEMSAKISFED", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25612-1", "uniprot_id": "AAD3_YEAST", "id": "P25612-1", "name": "Putative aryl-alcohol dehydrogenase AAD3", "aln": "---MIGSASDSSSKLGRLRFLSETAAIKVSPLILGEVSYDGARSDFLKSMNKNRAFELLDTFYEAGGNFIDAANNCQNEQSEEWIGEWIQSRRLRDQIVIATKFIKSDKKYKAGESNTAN-YCGN--HKRSLHVSVRDSLRKLQTDWIDILYVHWWDYMSSIEEFMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSYGKTPFSIYQGKWNVLNRDFERDIIPMARHFGMALAPWDVMGGGRFQSKKAMEERRKNGEGIRSFVGASEQTDAEIKISEALAKIAEEHGTESVTAIAIAYVRSKAKNFFPSVEGGKIEDLKENIKALSIDLTPDNIKYLESIV--PFDIGFPNNFIVLN-SLTQKYGTNNV---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8CG76-1", "uniprot_id": "ARK72_MOUSE", "id": "Q8CG76-1", "name": "Aflatoxin B1 aldehyde reductase member 2", "aln": "---MLRAASRAVGRAAVRSAQRSGTSVGRPLAMSRPPPPRAASGAPLRPATVLGTMEMGRRMDASAS--AASVRAFLERGHSELDTAFMYCDGQSENILGGLGLGLGSGDCTVKIATKANPWEGKSLKPDSIRSQLETSLKRLQCPRVDLFYLHAPDHSTPVEETLRACHQLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVEAELLPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNNWAETYRNRFWKEHHFEAIALVEKALQTTYGTNAPRMTSAALRWMYHHSQLQGTRGDAVILGMSSLEQLEQNLAATEEGPLEPAVVEAFDQAWNMVAHECPNYFR---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CG45-1", "uniprot_id": "ARK72_RAT", "id": "Q8CG45-1", "name": "Aflatoxin B1 aldehyde reductase member 2", "aln": "---MLRAVSRAVSRAAVRCAWRSGPSVARPLAMSRSPAPRAVSGAPLRPGTVLGTMEMGRRMDASAS--AATVRAFLERGLNELDTAFMYCDGQSESILGSLGLGLGSGDCTVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPRVDLFYLHAPDHGTPIVETLQACQQLHQEGKFVELGLSNYASWEVAEIYTLCKSNGWILPTVYQGMYNATTRQVETELLPCLRYFGLRFYAYNPLAGGLLTGKYRYEDKDGKQPEGRFFGNSWSETYRNRFWKEHHFEAIALVEKALKTTYGTSAPSMTSAALRWMYHHSQLQGTRGDAVILGMSSLEQLEQNLAATEEGPLEPAVVEAFNQAWNVVAHECPNYFR---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43488-1", "uniprot_id": "ARK72_HUMAN", "id": "O43488-1", "name": "Aflatoxin B1 aldehyde reductase member 2", "aln": "---MLSAASRVVSRAAVHCALRSPPPEARALAMSRPPPPRVAS--------VLGTMEMGRRMDAPAS--AAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR---------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : *: . : . . ...** : *: : *:: .:. **::** :*::*:* *: :.: * : : : * *:**.: **:*: .:* *: ..* * ::*** :*. .*:.* :::* *:**: : .:: :.** : .* *:: : * . . :* : .* : . :: . .: . ::: : : *.:. : : * : *:: .. : :::: ", "identical_positions": 45, "similar_positions": 98, "identity": "11.81%" }, { "cls_id": "homologset.agr.RGD:620312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24369-1", "uniprot_id": "PPIB_MOUSE", "id": "P24369-1", "name": "Peptidyl-prolyl cis-trans isomerase B", "aln": "MLRLSERNMKVLFAAALIVGSVVFLLLPGPSVANDKKKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKG-FGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVK-TSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSG-------------KIEVEKPFAIAKE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24368-1", "uniprot_id": "PPIB_RAT", "id": "P24368-1", "name": "Peptidyl-prolyl cis-trans isomerase B", "aln": "MLRLSERNMKVLFAAALIVGSVVFLLLPGPSVANDKKKGPKVTVKVYFDFQIGDEPVGRVTFGLFGKTVPKTVDNFVALATGEKG-FGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVK-TSWLDGKHVVFGKVLEGMDVVRKVENTKTDSRDKPLKDVIIVDCG-------------KIEVEKPFAIAKE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23284-1", "uniprot_id": "PPIB_HUMAN", "id": "P23284-1", "name": "Peptidyl-prolyl cis-trans isomerase B", "aln": "MLRLSERNMKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKG-FGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVK-TAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCG-------------KIEVEKPFAIAKE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W227-1", "uniprot_id": "Q9W227_DROME", "id": "Q9W227-1", "name": "Peptidyl-prolyl cis-trans isomerase", "aln": "--------MKLFLSVFVVA------LVAGVVVADDSK-GPKVTEKVFFDITIGGEPAGRIEIGLFGKTVPKTVENFKELALKPQG-EGYKGSKFHRIIKDFMIQGGDFTKGDGTGGRSIYGERFEDENFKLKHYGAGWLSMANAGKDTNGSQFFITTKQ-TSWLDGRHVVFGKILSGMNVVRQIENSATDARDRPVKDVVIANSG-------------TLPVSEAFSVAKADATD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35176-1", "uniprot_id": "CYPD_YEAST", "id": "P35176-1", "name": "Peptidyl-prolyl cis-trans isomerase D", "aln": "--------MKLQ-FFSFITLFACLFTTAIFAKEDTAEDPE-ITHKVYFDINHGDKQIGRIVMGLYGLTTPQTVENFYQLTISRDPKMGYLNSIFHRVIPNFMIQGGDFTHRSGIGGKSIFGNTFKDENFDVKHDKPGRLSMANRGKNTNGSQFFITTVP-CPWLDGKHVVFGEVLDGMDVVHYIENVKTDSRNMPVKEVIIVESGELETVPLDNKDAAKLQEEIKAEASEAAHDEL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P23285-1", "uniprot_id": "CYPB_YEAST", "id": "P23285-1", "name": "Peptidyl-prolyl cis-trans isomerase B", "aln": "--------MKFSGLWCWLLLFLSVNVIASDVGELIDQDDEVITQKVFFDIEHGEEKVGRIVIGLYGKVCPKTAKNFYKLSTTTNSKKGFIGSTFHRVIPNFMVQGGDFTDGTGVGGKSIYGDTFPDENFTLKHDRKGRLSMANRGKDTNGSQFFITTTEEASWLDGKHVVFGQVVDGMDVVNYIQHVSRDANDKPLEAVKIAKCG-----------------EWTPELSS------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. : . : :* **:**: * : **: :**:* . *:*..** *: . *: .* ***:* :**:****** * **:**:*: * **** :** * :**** **:********** .****:*****:::.**:**. :: *:.: *:: * *...* . :. ", "identical_positions": 80, "similar_positions": 49, "identity": "33.9%" }, { "cls_id": "homologset.agr.RGD:620314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0LPN4-1", "uniprot_id": "RYR2_RAT", "id": "B0LPN4-1", "name": "Ryanodine receptor 2", "aln": "--MADAGEGEDEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQSLSVRALQEMLANTVEKSEG-------KFMMKTAQGGGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYGNSS------WRVDAAFQQTLWSVAPISSGSE--AAQGYLIGGDVLRLLHGHMDECLTVPSGEHGEEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWGQPFRLRHVTTGKYLSLMEDKNLLLMDKEKADVKSTAFAFRSSKEKLDAG--VRKEVDGMGTSEIKYGDSICYIQHVDTGLWLTYQAVDVKSARMGSIQ-RKAIMHHEGHMDDGLNLSRSQHEESRTARVIRSTVFLFNRFIRGLDALS--KRAKLPTVDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFADVAG-REAGESWKSILNSLYELLAALIRGNRKNCAQFSGS--LDWLISRLERLEAS--SGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGVSEGSAQYKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHLWSGCIARTVSS--PNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAACYEAVLPKEKLKVEHSREYKQERTYTR-DLLGPTVSLTQAAFTPVPVDTSQIVLPPHLERIRERLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFCKLPEQERNYNLQMSLETLKTLLALGCHVGIADEHAEEKVKKMKLP-KNYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGIQQDVKNRRNPRLVPYTLLDDRTKKSNKDSLREAVRTLLGYGYHLEAPDQD--HASRAEVCSGTGERFRIFRAEKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDLELGSDERAFAFDGFKAQRWHQG-NEHYGRSWQAGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFDVG-DGFIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSN-HEHIEVTRIDGTIDSSPCLKVTQKSFGSQNSNT-DIMFYRLSMPIECAEVFSKSVAGGIPG-AGFYGPKNDLEDFDVDSDFEVLMKTAHGHLVPDR--MDKDKETPKPEFNNHKDYAQE----------------------------------------------------KPSRLKQRFLLRRTKPDYSTSHSARLTEDVLAD--------------------------------------------------------DRDDYEYLMQTSTYYYSVRIFPGQEPANVWVGWITSDFHQYDTGFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGESM----SPGQGRNNSNGLEIGCVVDAASGLLTFIANGKELSTYYQVEPSTKLFPAVFAQATSPNVFQFELGRIKNVMPLSAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISERQGWLVQCLDPLQFMSLHIPEENRSVDILELTEQEELLQFHYHTLRLYSAVCALGNHRVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMTEETKSITLFPDENKKHGLP-GIGLSTSLRPRMCFSSPSFVSISN---------------ECYQYSPEFPLDILKAKTIQMLTEAVKEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSVFKEAATPEEEGGAPEKEISIDDSKLE--VKEEAKAGKRPKEGLLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRYNEVMQALNMSAALTARKTKEFRSPPQEQINMLLNFK----DDKSECPCPEEIRDQLLDFHEDLMTHCGI-ELDEDGSLDGSNDLTIRG----RLLSLVEKVTYLKKKQAEKPVASDSRKSSSLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGLVRA-LPKTYTINGVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEITFP------------------KMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGLQSCQMLVSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAAMEEAIKIAEDP--------SRDGPSPTSGSSKTLDAEEEEDDTIHMGNAIMTFYAALIDLLGRCAPEMHLIHAGKGEAIRIRSILRSLIPLGDLVGVISIAFQMPTIAKDGKVVEPDMSAGFCPDHKAAMVLFLDRVYGIEVQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYLCTAVLPLLTRCAPLFAG-TEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEVCLLSICGQLRPSMMQHLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWSNFGAASEEELHLSRKLFWGIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVSMMEKQSSMDS--EGNFNPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKIQPLMKPYKLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGDSMALYNRTRRISQTSQVSIDAAHG---YSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKMELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDIFKFLQISGYAVSR-----GFKDLDLDTPSIEKRFAYSFLQQLIRYVDEAHQYILEFDGGSR----SKGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLCTGGHASNKEKEMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLDSVKSALRAFLDNAAEDLEKTMENLKQGQFTHTRSQPKGVTQIINYTTVALLPMLSSLFEHIGQHQFGEDLILEDVQVSCYRILTSLYALGTS---------KSIYVERQRSALGECLAAFAGAFPIAFLETHLDKHNVYSIYNTRSSRERAALSLPANVEDVCPNIPSLEKLMTEIIELAESG--IRYTQMPHMMEVVLPMLCSYMSRWWEHGPENHPERAEMCCTALNSEHMNTLLGNILKIIYNNLGIDEGAWMKRLAVFSQPIINKVKPQLLKTHFLPLMEKLKKKAAMVVSEEDHLK---AEARGDMSEAELLILDEFTTLARDLYAFYPLLIRFVDYNRAKWLKEPNPEAEELFRMVAEVFIYWSKSHNFKREEQNFVVQNEINNMSFLITDT--KSKMSKAA------ISDQERKKMKRKGDRYSMQTSLIVAALKRLLPIGLNICAPGDQELIALAKNRFSLKDTEEEVRDVIRSNIHLQGKLE------------------DPAIRWQMALYKDLPNRAEDTSDPERTVERVLDIANVLFHLEQ------------VEHPQRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPG----SELPEEDEAMKRVDPLHQLILLFSRTALTEKC-KLEEDFLYMAYADIMAKSCHDEEDDDG-EEEVKSFEVTGSQRSKEKEMEKQKLLYQQARLHDRGAAEMVLQTFSASKGETGPMVAATLKLGIAILNGGNSTVQQKMLDYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSGEKVLQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDIIDEQGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQISESDLNERSANKEESEKERPEEQAPRMGFFSLLTVQSALFALRYNVLTLVRMLSLKSLKKQMKRMKKMTVKDMVSAFFSSYWSVFVTLLHFVASVCRGFFRIVSSLLLGGSLVEGAKKIKVAELLANMPDPTQDEVRGDEEEGERKPLESALPSED------LTDLKELTEESDLLSDIFGLDLKRE-GGQYKLIPHNPNAG---LSDLMTNPIPVPEVQEKFQEQKVKEE-KEGKEETKSEPEKAEGEDGEKEEKAKDDKGKQKLRQLHTHRYGEPEVPESAFWKKIIAYQQKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSTS---------------SVVEGKELPTRTSSDAAKVTTSLDSSPHRIIAVHYVLEESSGYMEPTLRILAILHTIISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAALDFSDAREKKKPKKDSSLSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q401-1", "uniprot_id": "RYR2_MOUSE", "id": "E9Q401-1", "name": "Ryanodine receptor 2", "aln": "--MADAGEGEDEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQSLSVRALQEMLANTVEKSEGQVDVEKWKFMMKTAQGGGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYGNSS------WHVDAAFQQTLWSVAPISSGSE--AAQGYLIGGDVLRLLHGHMDECLTVPSGEHGEEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWGQPFRLRHVTTGKYLSLMEDKNLLLMDKEKADVKSTAFAFRSSKEKLDVG--VRKEVDGMGTSEIKYGDSICYIQHVDTGLWLTYQAVDVKSARMGSIQ-RKAIMHHEGHMDDGLNLSRSQHEESRTARVIRSTVFLFNRFIRGLDALS--KKVKLPTIDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFADVAG-REAGESWKSILNSLYELLAALIRGNRKNCAQFSGS--LDWLISRLERLEAS--SGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGVSEGSAQYKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHLWSGCIARTVSS--PNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAACYEAVLPKEKLKVEHSREYKQERTYTR-DLLGPTVSLTQAAFTPVPVDTSQIVLPPHLERIRERLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFCKLPEQERNYNLQMSLETLKTLLALGCHVGIADEHAEEKVKKMKLP-KNYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGIQQDVKNRRNPRLVPYTLLDDRTKKSNKDSLREAVRTLLGYGYHLEAPDQD--HASRAEVCSGTGERFRIFRAEKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDLELGSDDRAFAFDGFKAQRWHQG-NEHYGRSWQAGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFDVG-DGFIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSN-HEHIEVTRIDGTIDSSPCLKVTQKSFGSQNNNT-DIMFYRLSMPIECAEVFSKSVAGGLPG-AGFYGPKNDLEDFDVDSDFEVLMKTAHGHLVPDR--IDKDKETPKPEFNNHKDYAQE----------------------------------------------------KPSRLKQRFLLRRTKPDYSTGHSARLTEDVLAD--------------------------------------------------------DRDDYEYLMQTSTYYYSVRIFPGQEPANVWVGWITSDFHQYDTGFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGESM----SPGQGRNNSNGLEIGCVVDAASGLLTFIANGKELSTYYQVEPSTKLFPAVFAQATSPNVFQFELGRIKNVMPLSAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISERQGWLVQCLDPLQFMSLHIPEENRSVDILELTEQEELLQFHYHTLRLYSAVCALGNHRVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEFIVPMTEETKSITLFPDENKKHGLP-GIGLSTSLRPRMRFSSPSFVSISN---------------DCYQYSPEFPLDILKAKTIQMLTEAVKEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSVFKEAAVPEEEGGTPEKEISIEDAKLE--GEEEAKGGKRPKEGLLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRYNEVMQALNMSAALTARKTREFRSPPQEQINMLLNFK----DDKSECPCPEEIRDQLLDFHEDLMTHCGI-ELDEDGSLDGSNDLTIRG----RLLSLVEKVTYLKKKQAEKPVASDSRKCSSLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGLVRA-LPKTYTINGVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEITFP------------------KMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGLQSCQMLVSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAAMEEAIKIAEDP--------SRDGPSPTSGSSKTLDIEEEEDDTIHMGNAIMTFYAALIDLLGRCAPEMHLIHAGKGEAIRIRSILRSLIPLGDLVGVISIAFQMPTIAKDGKVVEPDMSAGFCPDHKAAMVLFLDRVYGIEVQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYLCTAVLPLLTRCAPLFAG-TEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEVCLLSICGQLRPSMMQHLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWGNFGAASEEELHLSRKLFWGIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVSMMEKQSSMDS--EGNFNPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKIQPLMKPYKLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGDSMALYNRTRRISQTSQVSIDAAHG---YSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKLELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDIFKFLQISGYVVSR-----GFKDLDLDTPSIEKRFAYSFLQQLIRYVDEAHQYILEFDGGSR----SKGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLCTGGHASNKEKEMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLDSVKSALRAFLDNAAEDLEKTMENLKQGQFTHTRSQPKGVTQIINYTTVALLPMLSSLFEHIGQHQFGEDLILEDVQVSCYRILTSLYALGTS---------KSIYVERQRSALGECLAAFAGAFPIAFLETHLDKHNVYSIYNTRSSRERAALSLPANVEDVCPNIPSLEKLMTEIIELAESG--IRYTQMPYMMEVVLPMLCSYMSRWWEHGPENHPERAEMCCTALNSEHMNTLLGNILKIIYNNLGIDEGAWMKRLAVFSQPIINKVKPQLLKTHFLPLMEKLKKKAAMVVSEEDHLK---AEARGDMSEAELLILDEFTTLARDLYAFYPLLIRFVDYNRAKWLKEPNPEAEELFRMVAEVFIYWSKSHNFKREEQNFVVQNEINNMSFLITDT--KSKMSKAA------ISDQERKKMKRKGDRYSMQTSLIVAALKRLLPIGLNICAPGDQELIALAKNRFSLKDTEEEVRDIIRSNIHLQGKLE------------------DPAIRWQMALYKDLPNRTEDPSDPERTVERVLGIANVLFHLEQKSKYTGRGYFSLVEHPQRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPG----AELPEEDEAMKRVDPLHQLILLFSRTALTEKC-KLEEDFLYMAYADIMAKSCHDEEDDDG-EEEVKSFE--------EKEMEKQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTVQQKMLDYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSGEKVLQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDIIDEQGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQISESDLNERLANKEESEKERPEEQAPRMGFFSLLTIQSALFALRYNVLTLVRMLSLKSLKKQMKRMKKMTVKDMVLAFFSSYWSVFVTLLHFVASVCRGFFRIVSSLLLGGSLVEGAKKIKVAELLANMPDPTQDEVRGDEEEGERKPLESALPSED------LTDLKELTEESDLLSDIFGLDLKRE-GGQYKLIPHNPNAG---LSDLMTNPVPVPEVQEKFQEQKAKEE-KEEKEETKSEPEKAEGEDGEKEEKAKDEKSKQKLRQLHTHRYGEPEVPESAFWKKIIAYQQKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSTS---------------SVVEGKELPTRTSSDTAKVTNSLDSSPHRIIAVHYVLEESSGYMEPTLRILAILHTIISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAALDFSDAREKKKPKKDSSLSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92736-1", "uniprot_id": "RYR2_HUMAN", "id": "Q92736-1", "name": "Ryanodine receptor 2", "aln": "--MADGGEGEDEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPPDLSICTFVLEQSLSVRALQEMLANTVEKSEGQVDVEKWKFMMKTAQGGGHRTLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSYGNGS------LHVDAAFQQTLWSVAPISSGSE--AAQGYLIGGDVLRLLHGHMDECLTVPSGEHGEEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRWGQPFRLRHVTTGKYLSLMEDKNLLLMDKEKADVKSTAFTFRSSKEKLDVG--VRKEVDGMGTSEIKYGDSVCYIQHVDTGLWLTYQSVDVKSVRMGSIQ-RKAIMHHEGHMDDGISLSRSQHEESRTARVIRSTVFLFNRFIRGLDALS--KKAKASTVDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFADVAG-REAGESWKSILNSLYELLAALIRGNRKNCAQFSGS--LDWLISRLERLEAS--SGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGVSEGSAQYKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGEEWGGNGVGDDLFSYGFDGLHLWSGCIARTVSS--PNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNIDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCYEAVLPKEKLKVEHSREYKQERTYTR-DLLGPTVSLTQAAFTPIPVDTSQIVLPPHLERIREKLAENIHELWVMNKIELGWQYGPVRDDNKRQHPCLVEFSKLPEQERNYNLQMSLETLKTLLALGCHVGISDEHAEDKVKKMKLP-KNYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGIQQDVKNRRNPRLVPYTLLDDRTKKSNKDSLREAVRTLLGYGYNLEAPDQD--HAARAEVCSGTGERFRIFRAEKTYAVKAGRWYFEFETVTAGDMRVGWSRPGCQPDQELGSDERAFAFDGFKAQRWHQG-NEHYGRSWQAGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFDVG-DGFIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWLSKRLPQFLQVPSN-HEHIEVTRIDGTIDSSPCLKVTQKSFGSQNSNT-DIMFYRLSMPIECAEVFSKTVAGGLPG-AGLFGPKNDLEDYDADSDFEVLMKTAHGHLVPDR--VDKDKEATKPEFNNHKDYAQE----------------------------------------------------KPSRLKQRFLLRRTKPDYSTSHSARLTEDVLAD--------------------------------------------------------DRDDYDFLMQTSTYYYSVRIFPGQEPANVWVGWITSDFHQYDTGFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGESM----SPGQGRNN-NGLEIGCVVDAASGLLTFIANGKELSTYYQVEPSTKLFPAVFAQATSPNVFQFELGRIKNVMPLSAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRISERQGWLVQCLDPLQFMSLHIPEENRSVDILELTEQEELLKFHYHTLRLYSAVCALGNHRVAHALCSHVDEPQLLYAIENKYMPGLLRAGYYDLLIDIHLSSYATARLMMNNEYIVPMTEETKSITLFPDENKKHGLP-GIGLSTSLRPRMQFSSPSFVSISN---------------ECYQYSPEFPLDILKSKTIQMLTEAVKEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSVFKEAATPEEESDTLEKELSVDDAKLQGAGEEEAKGGKRPKEGLLQMKLPEPVKLQMCLLLQYLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRYNEVMQALNMSAALTARKTKEFRSPPQEQINMLLNFK----DDKSECPCPEEIRDQLLDFHEDLMTHCGI-ELDEDGSLDGNSDLTIRG----RLLSLVEKVTYLKKKQAEKPVESDSKKSSTLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGLVRA-LPKTYTINGVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEITFP------------------KMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGLQSCQMLVSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAAMEEAIKIAEDP--------SRDGPSPNSGSSKTLDTEEEEDDTIHMGNAIMTFYSALIDLLGRCAPEMHLIHAGKGEAIRIRSILRSLIPLGDLVGVISIAFQMPTIAKDGNVVEPDMSAGFCPDHKAAMVLFLDRVYGIEVQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYLCTAVLPLLTRCAPLFAG-TEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEVCLLSICGQLRPSMMQHLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWGNFGAASEEELHLSRKLFWGIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVSMMEKQSSMDS--EGNFNPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSSKVQPLMKPYKLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGDSMALYNRTRRISQTSQVSVDAAHG---YSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKMELESKGGGNHPLLVPYDTLTAKEKAKDREKAQDILKFLQINGYAVSR-----GFKDLELDTPSIEKRFAYSFLQQLIRYVDEAHQYILEFDGGSR----GKGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLCSGGHASNKEKEMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLESVKSALRAFLDNAAEDLEKTMENLKQGQFTHTRNQPKGVTQIINYTTVALLPMLSSLFEHIGQHQFGEDLILEDVQVSCYRILTSLYALGTS---------KSIYVERQRSALGECLAAFAGAFPVAFLETHLDKHNIYSIYNTKSSRERAALSLPTNVEDVCPNIPSLEKLMEEIVELAESG--IRYTQMPHVMEVILPMLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLGNILKIIYNNLGIDEGAWMKRLAVFSQPIINKVKPQLLKTHFLPLMEKLKKKAATVVSEEDHLK---AEARGDMSEAELLILDEFTTLARDLYAFYPLLIRFVDYNRAKWLKEPNPEAEELFRMVAEVFIYWSKSHNFKREEQNFVVQNEINNMSFLITDT--KSKMSKAA------VSDQERKKMKRKGDRYSMQTSLIVAALKRLLPIGLNICAPGDQELIALAKNRFSLKDTEDEVRDIIRSNIHLQGKLE------------------DPAIRWQMALYKDLPNRTDDTSDPEKTVERVLDIANVLFHLEQKSKRVGRRHYCLVEHPQRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAKPG----AEPPEEDEGTKRVDPLHQLILLFSRTALTEKC-KLEEDFLYMAYADIMAKSCHDEEDDDG-EEEVKSFE--------EKEMEKQKLLYQQARLHDRGAAEMVLQTISASKGETGPMVAATLKLGIAILNGGNSTVQQKMLDYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSGEKVLQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQISESDLNERSANKEESEKERPEEQGPRMAFFSILTVRSALFALRYNILTLMRMLSLKSLKKQMKKVKKMTVKDMVTAFFSSYWSIFMTLLHFVASVFRGFFRIICSLLLGGSLVEGAKKIKVAELLANMPDPTQDEVRGDGEEGERKPLEAALPSED------LTDLKELTEESDLLSDIFGLDLKRE-GGQYKLIPHNPNAG---LSDLMSNPVPMPEVQEKFQEQKAKEEEKEEKEETKSEPEKAEGEDGEKEEKAKEDKGKQKLRQLHTHRYGEPEVPESAFWKKIIAYQQKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSTS---------------SVVEGKELPTRSSSENAKVT-SLDSSSHRIIAVHYVLEESSGYMEPTLRILAILHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAALDFSDAREKKKPKKDSSLSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDTPDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T6W5-1", "uniprot_id": "A0AB32T6W5_DANRE", "id": "A0AB32T6W5-1", "name": "", "aln": "---MDIGEAEDEIQFLRTRDELVLRCCSSGP-HQQKLCLAAEGFGERLCFLESTSNSKNVPADLCVCVFVLDQCLSVRALQEMLANRED------------LCTASHEAAGRRTLLYGQAVLFRHAYSDMYLCCLSTSGLSSDKLAFDVGLQEDTKGEVCWWTVHPASKQRSEGEKVRVGDDLILVSVSSERYLHVSWTNGEGNDSGVGRVDAAFQQTLWSVAPVSSGTV--KTQGHVRGGDTVRLLHGHTDECLTIRAAKHKPDQHRSVHFEGGLVSLQARSLWRLETLHVVWSGSHIHWGQPFRLRHLTTGSFLGLIHDQGLQLVERDRADVKCTAFAFRASKEEIAESSDYVKRRDGMGAPEIKYGDSLCFIQHVGTGLWLTYQTTDSKRQKESVSQ-RQAVLQAEGHMDDGITLSRSQREESQAACLIRSSVLLFSQFISRLDDVT--QKENITNFNLPIEMIRLTLQDLLGYFHCPEKGQDHKIRQGDIGALKNRQNLFQDEGIILLVLDCIDHLHVYNSAAHFAEAVG-KEAGECWEGVLNAFYELLAALIRGNRNNCAQFSGS--LDWLVSRLERLEAS--SGILEVLHCVLVESPEALNVIKESHIRTIISLLDKHGRNHKILDVLCSLCVCHGMAVRSNQHLICDTLLPERDLLLQTRLINQVSSVRPNIFLCTRDDSAQYKKWYYEVVVEKAEPFVTAEPTHLRVGWASTEGYRPSPTGGHDWGSNGVGDDLCSYGFDGLQLWTGGVGRRVSS--PNQHLLREDDVISCCLDLSATCISFRVNGQPVQGMLENFCVDGLLFPVVSFSAGVQVRMLFGGRQGEFRFLPPAGFSPCAEALLPKTRCKLELCHELTRNHTETQRDLLGPVVPINPVTFTPVPVDSSQVEYPPQLEQIRERLAENLHELWLIDKIEQGWTYGPVKDEGKKVHSCLVEFSKLPDQERIHSLQSSEDILRTLLAFGVHIGLSDEHAEENVKYVRLS-NKYELWNGYKPAPVDQSRVVLTDAQGELVEYLAENEHNIWARERIRQGWSYGPQQDVKFKRSTQLVPFYLLDERYKQAGRDAMRDALGTLLGFGYTVEPLEKE--HASSSSVKSVGAERFRIFRLEQLFAVHSGKWYFEFEAVTDGEMRVGWARPGCKPDVDLGSDDQAFVFDGSKGQWWHGG-AERLGGCWKRGDVIGCLLDLTTDTMMITLNGELLLNSHGSEFAVKDLIKS-DGFLPVCSIGINQVGRLNLGCQIESLKFFNVCGLQEGYQPFGLNMSKDLPLWMSWRAPLFIPIQDN-HPNIQVLRVDGTVNNTPCLKVTKRVFGHEERGSGSVGFYRLSMPIECAQVFCGPGDASVPTSSAAICHLRDPEDGEVDSDFELLMKAHR-------------YAGSRDELNNHKDHSQE----------------------------------------------------KPSRLKQRFMLKKKQELNTSHSSARLLEEVLAI--------------------------------------------------------EKNEENRLVRCTTYYYSVRIPFSQEPSCVWVGWVTSKFSHHDVSFDLDSICTVTVTLGDEWGKVHESVKRSSCYMVCAAEGS----SLSHSRSS-NGLEIGCLVDTATGLLTFTANGKEITTYYQVEPGTKLFPAVFAKATSSNVFQFELGCIKNVMPLSAGVFRSERRNANPQCPPRLCVQHLTHTRWTRVPDHTQSVEMSRLEERYGWRAQCSHIQQIMTLYIPEESRCVDILELSESHDLLKFHNHTLLLYSALSAHGNTHVSHALCSHVDQSQLLFALQCSRMPGHLRTSYYNLLINIHLDAHASARQTMNHEYIVPMTN-TQSITLYKSNEKVERFP-GSDRSTSLWPKMHFTSPCFIRSNNKIDLVDGDEGRVLWSSLRQDSPEIPLDVLKAVVIAMLKEAVMVVGQGVRDPTGGSVELLLVPLLNLIHTLLLMGVYQGADLEAVFSLILPSEYMRATQRTEET----DELGERDGGAE-----EKEKGDWKYDVLLQMKLPEAVKLQVCQLLKYLCDCQVRHRVEAVISFSGDFVGHLQEDQRFRYNEVVDALNMSAALTARKTKEFRSPPQEQINMMLSFR----EDCLECPCPEDIQDLMWEFHQDLMSHCGI-EIESGSENENEDDLSIRN----HLHGLVDKIMHLKRRMSGLPEEIAS-KPVSLQQLISETMLHWAQEETIEDPDLVRAVFSLLHQQYAGLHGQMSAPLQKAYCISQTSVEDTLHLQWALACIRSLLKARMGKEEEECMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLDARESKEIIFP------------------KMVAHCCRFLCYFCRISRQNQKAMFDHLSYLLDNGNVGLASPSMRGSTPLDVAAASVMDNNELALSLTEADLEKVVQYLGGCGLRSCALLVSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENAYVVVRLLIRRPECFGPALRGEGANGLLATMEEAIRISNQ----------QDGTTAHSSSRTLDTLDEDDHDVIHMGHAIMTFYSALIDLLGRCAPETHLIEAGKGEAIRIRAILRSLVPREDLEGIINIPFSLPVVNSDGLVVEPDMSRMFCPDHKAAMVLFLDRVYGVQDQQFVLRLLKFGFLTDLKAAVNMDTTGLGGTDMALAINRYLCVAVLPLLSKYSSLLCDSSSSRSGPVDELLQGVYSLSKASGLTKAQREAIQDCLLAVCGKLKPSMVQPLLRNLVFDVPQLPENSKMPLKLLTNHYEQSRKYYCRSYGFGDFGSASEEELCLTRRLFWGIFSALAKKSYDADLFKLALGCLSAVAGAIPPDHLDLSCTGGRERHSVMDS--ERGFCPQPLDTLNVTIPESLEFVVNKYAEHTHEKWSMEKFGNGWVHGEQLSESSKVHPLLKPYRALSEKDKECYRGVIKETVKCMLVLGWTIKRTNEGESHGIHNPARRISQSGKLSFEGAST---FSPKPVDTSSVTLTWDQYAMAERLAENYHHIWAARKLQELESKGGGSHPLLVPYDALSVKDKSRVRDKAQDVLKFFHVNGYSVKR-----NREVADADSPAIASRFAYGLIQQALRLTERAQESVIELDVAQARGQINKAERVPHEQQIHFFIKVLLPLLDQYFKNHHLYFMSTTMSSLRDGCQSTSKEKEMVTSLFCKLGSLARRRISIFGNDALALVNCLQILAQSLDGRMLMKTTSESVRGSIGSFFEAAAEDLELMVENVTLDGLN--RAQKRGDPELIAYTTTALIPVLSAIFQHDSQRQSGAGLILDEVQSCCYRILSSLYILGTC---------SGSFIERQRSVLGECLAALSAAFPVCFLELS----DLHSHFDTLSNE--------GIEEKACKLLPNLHEAFLEVEELAGAGSSARHALLLRVTEVTLPLLCSYVSRWGEVDNQAS---QEGHCSSVTPQHANALLGYILSIIHAHLGTSDSAWMKRLAVFGQPIINKAEPHLLKRHFLPLMEKLRKRAESVLLEEEHLK---MEGRGDVSEQELDIQERFTVLVQDIYAFYPLLIPFIDLHRMSWLREVNADAEKLFSLVAEVFIFWAKSHNFKWEEQNFVVQNEINNMAFLVNSS--KSRMNKGG------VFCQERRKVKRKADRYSTHTSLIVAAPKKLLSVAMNGCCHGDQGLVSHAKSRFAQRDTEDEVRAYIHS-----------------------------------ILQQDLCGNSVDP----LRVERILSIARVLFHLDQ------------VEHPQKMKRPVWYKMLSKQRKRAVVACLRMAPLYNLPRHRAVNLFLQGYERVWLKAENDSPEDRLIEDLAKAAH--VEILKEGAEQRNRIDPLHQLINLFSQCALTQRS-KLEEDGLYMCYAEIMAKSCQSEEEQD--EDGLKSFE--------EKEMEKQRLLYQQARLHDRGAAEMILQKLSASRGDMGPMVAATLKLGIAILNGGNTSVQQKMLGYLRRKKDVGFFHSLAGLMQSCSVLDLNAFERQIKAESLGVGAEDNSGDKVMADEQLTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDERGQHNFSKAISVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSRDSSQIELLKALMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSSNVEMILKFFDMFLKLKDLTSSEAFHEYDPDSKGLISKKDFQRAMEVFKRYSQSEIEFLLSCAEMSESELLDYPDFVTRFHEPAKEIGFNMAVLLTNLSEHMPNDARLQNFLELADSVLKYFHPHLGRIEILGSGKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNKGGEKEKMELFVNFCEDTIFEMQLAAQISGTESGEELKAKKGKEEKEVQKTETLP-----------------EDQRMTRDLNCFSVRNIRKHIKSISMKSIISVIFSLFYNVLLFITHAFLGLLWFCLYLLYHIFLSGWIIDVAKEMKLTDLFGDLRDPTMVEAIGVQDAFRENDNQARVFSSRGNLRGMSLDLSAVSRDPQLLTDIFGLCLKRQ-GGKYTLSSGDHSAS---LDEFLNTSKYQVEIRE--EDFHAVQD-----EEEDTETKKAFCSDEDKHNKEK--KTKRRIRKLSSSNPDETEIQEWAVWKMISSQKTKLLNCFARNFYNMRLLALFLAFAINFILLFYKVSS-------------------------TTDDVEIAFHDESTKSSQE----VYFELEENSGYMKMILHCLAVLHTIISLCCIIGYYCLKVPLVIFKREKELARKLEFDGLYITEQPSEDDIKGQWDRMVINTPSYPSNYWDKFVKRKVMAKYGELYGSARVSELLGLDKAALDFSSGAQERKRPMQKGILVRLNTTDVKYHIWKLGVVFTDNSFLYLAWYMFVSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGEPMDMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEFEFYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNEYFDTVPHGFESHTLQEHNLANYLFFLMYLINKDVTEHTGQESYVWKMFQERCWEFFPVGDCFRKQYEDQLS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24498-2", "uniprot_id": "RYR_DROME", "id": "Q24498-2", "name": "Ryanodine receptor", "aln": "MAEAEGGSEQDDVSFLRTEDMVTLSCTATGE----RVCLAAEGFGNRHCFLENIAD-KNVPPDLSQCVFVIEQALSVRALQELVTAAGS-------------ETGKGTGSGHRTLLYGNAILLRHHNSDMYLACLSTS-SSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLHTTKENEQ------SIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHG-GDECLTIPSTWGREAGQNIVIYEGGVVMAQARSLWRLELARTKWTGGFINWYHPMRIRHITTGRYLGVNDSNELILVKKEEASIATTTFCLRQEKDDEKKVL-EDKDLEVIGSPIIKYGDTTVIVQHCETSLWLSYKSYETKKKGVGKVEEKQAILHEEGKMDDCLDFSRSQEEESKTARVIRKCSSLFTQFITALETLQSNRRHSIFFQKVNLNEMVMCLEDLINYFSQPEDDMEHEEKQNRFRALRNRQDLFQEEGVLNLILEAIDKINIITSQGFLASFLAGDETGQSWDLISTYLYQLLAAIIKGNHTNCAQFANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEKHGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTLLVDHVASIRPNIFVGRVDGSSMYQKWYFEVTMDHIEQTTHMMP-HLRIGWANTSGYVPYPGGGKKWGGNGVGDDLYSFGFDGAFLWTGGRKTLVVDALPEEPFIRKGDVIGVAIDLSVPIITFTFNGVKVRGSFRDFNLDGMFFPVMSCSSKLSCRFLFGGDHGRLKFAPPMGFSALVQCLMPQQILSLDPCFYFG---NLAKNVLAGPWLIEDDTAFVPKPVDTTGVTLPSSVDQIKEKLAENIHEMWALNKIEAGWSWGEHRDDYHRIHPCLTHFEKLPAAEKRYDNQLAVQTLKTIISLGYYITMD--KPPARIRPVRLPNEIFMQGNGYKPAPLDLSAVTLTPKLEELVDQLAENTHNLWARERIQQGWTYGLNEDSENHRSPHLVPYAKVDEAIKKANRDTASETVRTLLVYGYVLDPPTGEGTEALLAEAQRLKFAGFRTYRVERNYAVTSGKWYFEFEVLTSGPMRVGWARADCYPGAMLGSEDTSWAFDGHNVTKMHAGSIEHFGVRYEAGDVIGCFIDVKEQTISFSLNGELLMDALGGETTFADVTAEGVGFVPACTLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFENTEEMPDCRIDVTRIPGGADTPPHLKISHNTFETMEKAN--WEFLRLSLPVTCMGEFISEQEKARRWDEIKNRQYRLMREAEIAAQMQVQTQAAHMDHMLKGGFNMNDIKGLTRNFDEHADAEADHMMRGPNRPPRKGSLTRNITFETDMSAALDEMQRSTSVLDMNGLGEEMDDKKKRGRSPFKFFSKKSRDQSREKMGARTLDTSLERRNTVAHGRNVVNQQMTTRAPTLRLNNAEIPPSPVPQGPKQLSGSNLGQQPVETSGDEMFDAECLKLINEYFYGVRIFPGQDPTHVYVGWVTTQYHLHSREFNKNKVRRGSVYIEDDYEMAIERIDRQSCYVVRADELFNEVTQDASGKGASQGMFVGCFVDTATGIIRFTCEGKDTSHRWMMEPDTKLFPAIFVEATSKEILQIELGRTPTTLPLSAAVLPTSDKHINPQSPPRLKVQCLRPHQWARVPNTALQVHALKLSDVRGWSMLCEDPVSMLALHIPEEDRCIDILELIEMDKLLSFHAHSLTLYAALCYQSNYRAAHALCQHVDQKQLLYAIRSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYITPLGAELKEL--YSDEEMQHSLRSLVTESVRPQLRMTEITPPVIATSSMPSVSS----EPIPDIDQLYSPKFPLEVVRQFVMEALKDAVEINQVHNRDPIGWTNENLFLPLIKLTDRLLLVGVLTDEDVQRLLVMIDPETWDQAFER--------------------------EGKDEHRKGLLTMKMAEGAKLQMCYLLHHLYDTQLRHRVESIIAFSHDFVGDLQTDQLRRYIEIKQSD-LPSAVAAKKTKEFRCPPREQMNQILCFKNLEPDDQDNCTCGLELRGRLGDFHDSLMQKVSLNALQEPDGVEGTAIEEVKTGPITKIYNFINTVKELEEGPKEVEEPEKKTPEEVFRKVLIKTIVSWAEESQIENPKLVREMFSLLLRQYDTVGELVRA-LEKTYVINTRARDDVAEMWVGLSQIRALLPVQMSQEEEELMRKRLWKLVNNATFFQHPDLIRILRVHENVMAVMMNTLGRRAQAQSDAPTQSEVAEGAPSKEKDTSHEMVVACCRFLCYFCRTGRQNQKAMFDHFDFLLDNANILLARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSNSELVEKGYPDLGWDPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPECLGPALRGEG-EGLFRAIVEANRMSERISDRCKMQDEAEGTIAGLNFTHPLPEGEEDEDYIDTGAAILNFYCTLVDLLGRCAPDASVIEQGKNESLRARAILRSLVPLEDLQGVLSLKFTLSQTAPGEEKPKSDMPSGLLPNNKQSIVLFLERVYGIEAQDLFYRLLEDAFLPDLRTATILDKSDGSESDMALAMNRYIGNSILPLLIKHSKFYNE-AENYASLLDATLHTVYRLSKNRMLTKGQREAVSDFLVALTSQMQPAMLLKLLRKLTVDVSKLSEYTTVALRLLTLHFDRCAKYYGSTQGQGSYGASSDEEKRLTMLLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNTDEDYYGRQMGAPDQPQYMPNPIDTNNVHLDNDLNSLVQKFSEHYHDAWASRRLEGGWTYGDIRSDNDRKHPRLKPYNMLSEYERERYRDPVRECLKGLLAIGWTVEHSEVEVALNHRGSTRRQSKPQINEFQNEGSPFNYNPHPVDMSNLTLSREMQNMAERLAENSHDIWAKKKNEELNGCGGVIHPQLVPYDLLTDKEKKKDRERSQEFLKYMQYQGYKLHKPSKGGAVEEGGATQAAVELRFSYSLLEKLIQYLDRATINMKLLKPSTTFS--RRSSFKTATRDIKFFSKVVLPLMEKYFSTHRNYFIAIATATNNIG-AASLKEKEMVASIFCKLAALLRNRLSAFGPDVRITVRCLQVLVKGIDARTLTKNCPEFIRTSMLTFFNQTSDDLGNTILNLQDGKYSHLRGTHLKTSTSLGYVNQVVLPVLTAMFDHLAACDYGSDLLLDEIQVASYKILAALYHLGTDGTLTHDRKYLKTEIERHRPALGSCLGAYSSCFPVAFLEPHLNKHNQYSLLNRIADHS---LEAQDIMVKMESCMPNLETILAEVDQFVESD--KTYNDAPHIIDVILPLLCAYLPFWWSQGPDNVSPTSGNHVTMVTADHMNPLLRNVLKMIKKNIGNDNAPWMTRIAAYTQQIIINTSEELLKDPFLPLAERVKKRTENMLHKEDSMRGFIKSATDDTSQVETQLQEDWNLLVRDIYSFYPLLIKYVDLQRNHWLKDNIPEAEELYNHVAEIFNIWSKSQYFLKEEQNFISANEIDNMALIMPTATRRSAISEGAPAVGGKVKKKKKNRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRYLKKMPEYDVIEFARNQLTLPDKLDPSDEMSWQHYLYSKLGKTEEPVDEQALEKANVNSNEKGKDKTQETVDRIVAMAKVLFGLHM------------IDHPQQQSKNVYRSVVSIQRKRAVIACFRQTSLHSLPRHRACNIFARSYYEQWLQEENVG-QEVMVEDLTQTFEDSEKSKKEGEETDSKPDPLTQLVTTFCRGAMTERSGALQEDLLYMSYAQIAAKSTGKEEEEGGDEEGGEGGEEGEGTSIHEQEMEKQKLLFHQARLSNRGVAEMVLLHISASKGIPSEMVMTTLNLGIAILRGGNIDIQMGMLNHLKEKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSEGAAGEKNMHDAEFTCALFRFIQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAGKANFFKAIEVASQVFNTLTEVIQGPCTLNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLADLIESPSFHEVDMKNEGWVTPKDFREKMEQSKNYTPEEMDFLLACCERNHEGKIDYRAFVEHFHEPSKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEILGSSKRIERVYFEIKDSNIEQWEKPQIRESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASGLMATDDGGGNVKRDTAYSSYMSEEEEERAARDP--IRRTITAVKEGLKFGVHMLSPANIKHQIGVMQTKSIPELIVGFFKIIFYIFYYTGYAHFCVVRYIFGILLNLMRG-------------------PAPEQEEEPVVEEETFGRALPPLP-----------------LEEPPGTVQAFGLDINKEENGMYKVVVHESPANSSMEEGGESSPEDGAAASGELVEGEPHQEPISIVDLLGGEAAKKAAQERQEAQKAQEAAMAS-IEAEAKKSSSAPQETPAVHQIDFSQYTHRAVSFLARNFYNLKYVALVLAFSINFMLLFYKVTSFTEEADSSAEEELILGSGSGGGADITGSGFGGSGDGGSGDGEMEDEIPELVHVDEDFFYMEHVLRIAACLHSLVSLAMLIAYYHLKVPLAIFKREKEIARRLEFEGLFIAEQPEDDDFKSHWDKLVISAKSFPVNYWDKFVKKKVRQKYSETYDFDSISNLLGMEKSTFAAQESEE-------TGIFKYIMNIDWRYQVWKAGVTFTDNAFLYSLWYFSFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEED-EEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYEVYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPVGDCFRKQYEDELSGGGGGG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. :*::.**** * :.* * :: ::********:* ****. :: ****.**. *.**::*.********::: . . ..*:******:*:*:** *.***.***** *.***:*******.: **.****:************************::***** : * . *:*:*: * *** * .:* *:: ***.:*::** *****: : :. * :*** * :******** :. *:*..*.* :*:*:**:*** :*.: ..: * *:.::.*.: *:* :* .*:. * : :*:. *****: :** *.***:*:: : * . : ::*::: **:*** : :****.***::* :**. **.:** *: : :: . .: :: : : *:**:.** *:. :*: :*. : **:***:***:**:: *:*:.**:::: .* ..:*. . *:*:.*. : . :*:****:*:**:.*****:.* *:**.*** :* **:*:******::******:::: **: *****:****: *:********* :*:****.*: *** *** ::***** *:::*:*:*****: :.*: *:***:*: ::: * . . ***:***.*.** * * **..**.******* *:**** **:* * . *:: ::* .***. .:***.. *:* .** *:* :.:* :**::***:* *: :. *:*:** :*.::* ** *::. :.::*: .:: . . :: * ** : .:*.* ***:: : *. :::*:*:****:**:* ::*** ** :* :*: :: *.**..* *** *: :. * : : *:*::::* :: : :. .:: ::*. : : .******:* * : ** :*: **** **:***:**:***:** ::* : :*..:***: :*: *::.:*: ::: *** :** ::. : .* :.. ** :* *: :** :*:******.:* * *****:*..* *. ***:: ::.*** : * * *: * :: ***:**::*:. .*: ::****:*:: *.* :. *. **:*.*::*: * .*: * ::.:**:*. *******:** :* : :. * : * * . . .*:* *: * :..* **:::. * : . * ***:*: * * . . .: : ::::: :: : ::::* * : * .* :*: ::.: .** : * : : : * . *:*.*** .*:*: *:***:*:.: :. *: : : :* : *: . * :.*..**:* * * . . .:. :*: :**.**:*:*:: * .:**: : : :**.******:*.:*** :::*:*** ..:****.:: :. :: **.**** ** * *:*:*: .*. ::.: ** * . .:::*:****.*.:***** * ..**.** *:* **:*:. .* :.:****.***: ***:*:. . *.* ** .:*:*** :**.::*:: ::*:*.*: :.: : .:: . : *. :* :* .: .. **::**:::: .: *.:** *** * : * *::**::* **::*: . *:: :: :* *. : .* : . . ** **:.* .***:* **::* * *:***:*::::** ***..** :* ** *: :: :.:*::*:**:***.**:**:* :* *: :* :*.* :::. : :**:.** : .: ::. . :. :: :: .:::.: *:. . ::::: :*:: **:*. **:*.*** :* ** :** : : * * *:* *. : :*. .: .*. **:** .:*.:***: * : * .::** .*:***:*:* * :**.** **:*.*. . : * :**. ********** .**********:.:**:*..: ** *::********* :*:*:*.****:* * ***:. **. ***:* **.*****:**:************:.*: ********* :*:*********:******** :**: :: ** :::: :*. . . *::.* *. * **:.**.:*:********: :*. **.*::* *:*****:* ** *::.: * :. . :.**. : *::* ::****:****:: *::. :**: .**.**::*. :*.: . :*****:***: ::**** : : : :. :. :* *: ** *** ***.**:::. *::: .:::*:*: ***.*..**. * * :.:.*:*** *:::. *** . * ..:*::*:** *: ** .**.:*:: .*: :** ** ** *:. *:***: . .. *.: : : *:*:** *: : :.*: .::*::** *: *: :: .** :*: *:..: :* :***. *** ::* ** ::* :* :*. ** ::::. : . :** *:. ..: :.*:.:* *.:**: : *** :*** *.*** :* **:. ** ** ***** *: *:* : *:::*:.:*::: .** : : : .:: **:*.:::: :: :.* : :. . :.. . ::*:** **:***:::**..*: **:: : . * :: ******:*:****. * *.*:* ** *. *.**::* : :*.* : *. : :: :: :*:: :::** : *: . . * . : *.. .::*:*:::*:* . : * .*:*:::* ..*:**::** *** :**:*..**.**.* :..**:.*** : :* : :.. . :*.*. : *: ::. :. : : :* **:**:*:. * . . : : :..:* *.** :*.:* ::* .:..**.*:*.: * ** :.. .*** **** *:::*:: :: :*: :: .. .* *: * : : :. *.:*:*:****** ::* :* **:: .:**:*: ***:* *:**: * *****: ***:**:::: : :* :.:.. : :::.: *:: . . ::**:**. *:**.:.:* . :* *: .*.*: : .* :* :. :: .. . *:*:: :*.*** *. ::***: .: *: .::* ******:**:* :.*:.****** *:* :.* . *:: *: :: ::***::. * * .: *** **: *.: *:*::. *:** ***.**:* *** .**::. *: :. * *:*****:**::**** :**.***:* :***:* . ** :**:******.*** :* **.:*:.******* *:****:*******:****: ***.**: :* :*:* : * ::** ****:** ***** ::*******:**.****::*.*******:**** ****:**.*::** *: ** ***.**.******** ****** ***:********** ***.:*:*** ***:.***::*** *::*****:.*:******************* ****:.***:***:******* ** .* :*:* * ..:* :: :**:. ** *.*: .* :***:*.* ... :** ** :****:*:****:*************:.** *** * ***:**.*.******:**.**********.:*. ******::**** *::.:*.:**:***:* *******:**** *: : :: . :. .. .: : *. .::: ::. :: .:: :*. : :: : : : :: :: . * * : . . .:. : *** :::: .* *.: : *. . ... : . :: : *. * .: :: :* : :. . . .: . : : :. :******:: :**.:**:***:******:: * . : * ... . ::*. **: *: * **:::*: :*.** *****.*******:**:***:**:*:***.:**:*.:**::**.: *:* ********:** **.* *. :*:***::*::: ... : ..: : . * :*::** **.****:*** **: .**:*::***********:*:*********.************* **:::**:***:********* :.** : * **.*****::**:* ************ ** **::*.**************:******************** *.**::**::*****:*:::** *****::*. :*******:****:**** **:****:***:*:*:*.*:***.**********:*. ", "identical_positions": 1925, "similar_positions": 1544, "identity": "36.56%" }, { "cls_id": "homologset.agr.RGD:620315", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55035-1", "uniprot_id": "PPIG_RAT", "id": "O55035-1", "name": "Peptidyl-prolyl cis-trans isomerase G", "aln": "-----MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELVPKSKVKKEEKKRHKSSSSSSSS--DSDSSSDSQSSSDSSDSESASEEKSRKRKKKHRKNSRKHKKEKKKRKKSKKSPSSESEADNVDAQPQSTVRPEEIPPIPE--NRFLMRKSPPKADDKERK-----NRERERERECNPP-NSQPASYQRRFLVTRFGRKIKGRGPRRYRTPSRSRSR------------------DRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKEKKITDHRHMSESPNRKIEKEKKVKDHKSESKERDIR----------------------RNSEKDDKYNKNKVKKRGKSKSRSKSKER-SKSKERDSKHSRHEDKRVRSRSKERDHETTKEKEKQLDSKGKDQERSRSKENSKQVESKSNEHDHSKS--KEKDRRAQSRSRERDLT--------KSKHSYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKE-------------YHRYREQEYRRRGRSRSRDRRTP-GRSRSKDRRRRRRDSRSSEREESQSRNKEKYRSQDSKSSHRKENSEGEKRMYSKSRDHSSSNNNREKKADIDQSPVSKTKQSSQDNEVKSSTLKNQEDEKTRSPVEKENQK---SKGQENDHVHDKNKKCDHESSPGTDEDKSG-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AR02-1", "uniprot_id": "PPIG_MOUSE", "id": "A2AR02-1", "name": "Peptidyl-prolyl cis-trans isomerase G", "aln": "-----MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSS--DSDSSSDSQSSSESSDSESASEEKSRKRKKKHRKNSRKHKKEKKKRKKSKKSPSSESEAENVDAQPQSTVRPEEIPPIPE--NRFLMRKSPPKADDKERK-----NRERERERECNPP-NSQPASYQRRFLVTRSGRKIKGRGPRRYRTPSRSRSR------------------DRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKEKKITDHRHMSESPNRKVEKEKKAKDHKSESKERDIR----------------------RNSEKDDKYNKNKVKKRGKSKSRSKSKER-SKSKERDSKHSRHEDKRVRSRSKERDHETTKEKEKPLDPKGKDQERSRSKENSKQVESKSNEHDHSKS--KEKDRRAQSRSRERDLT--------KSKHSYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKE-------------YHRYREQEYRRRGRSRSRDRRTP-GRSRSKDRRRRRRDSRSSEREESQSRNKDKYRSQESKSSHRKENSEGEKRTYSKSRDHNSSSNNREKKADREQSPVSKTKQSSQDNEVKSSTLKNQEDEKTRSPVEKENQK---SKGQENDHVHDKNKKCDHESSPGTDEDKSG-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13427-1", "uniprot_id": "PPIG_HUMAN", "id": "Q13427-1", "name": "Peptidyl-prolyl cis-trans isomerase G", "aln": "-----MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPE--NRFLMRKSPPKADEKERK-----NRERERERECNPP-NSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSR------------------DRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIR----------------------RNSEKDDKY-KNKVKKRAKSKSRSKSKEK-SKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKS--KEKDRRAQSRSRECDIT--------KGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKE-------------YHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQK---SKGQENDHVHEKNKKFDHESSPGTDEDKSG-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAW1-1", "uniprot_id": "Q9VAW1_DROME", "id": "Q9VAW1-1", "name": "peptidylprolyl isomerase", "aln": "MTVNKRDAGATRPRCFFDISLGGLGMGRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKDFMVQAGDFSAGNGTGGESIYGGTFEDESFEKKHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDNIHVVFGQVISGQELVRQLEGLPVDRNSRPLQDAAIANCGELVRQTKAKKEKKHKRRSTATEDSN--------SEESEAEAKVVRKAKKKKRSRKDTKSQSDSEDNETSRGNGKHDQTPQDDDEDREEGELHPLVTITKIDPNEIPEVSNKFLMRAERSKSLDREERGARGQDRDRGKDQDRDRSRNNFGWSKKQAPPTSRSGRIVKGRGVFRFRTPSRSRSRSTTPPHWKHAQKRTIKLSDLERIEEESKMREEEMKRREHERKRRHEEATKNPKQSFFELSHASTYGGKITPDRFSPEHKAKSKDTADRGKAKEREKAGEKDKARDVTPVKRRKSMDMNALDYEQQTESEVESEDEEQLKVKPPSKQDIRVEPSTSKDRNAKRDERKPTEEKAKPKRSRSRSPRRQSPARRQQRSPARRPGQNYNQNQNQNQNQNQNQNQLNRGNRRNPFADRDRRRRSRSQDNEYRNRYPLSPIRGRGSPSGDRRRQQRSRSQNRRQDSPSQRRQLSPGRKRQDSPSKKRPNSTERKWRDSPERKRDDSHDRKREASPNWKRDDSPARKRKDSANRKREDSQDKKIQDSKRQEDSAGKKREDSPSKKRKDSDKKRQDSPVKRQESPGRKRQDSPERKRRDSPDRRRKDSPARRRQESSGRRRQDSDGRRRRESSGNRRSRSRGRWHSSSRSRSPSTSRSRRRRSRSPLPKLTSALPMSEEREKAAREKMQKRAEAAMLMKEHMRNEIAKEEERRMEKQRQDDLDKERTTRELNELERLKAETLRKLHEEDSVDPDAAASAGSASKTDATSTGAKSKRDSSSENRHREKKRKHKKSKKSSGRSDND", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . ********::.. **:*****.**.***.****.******* * * * *:**. :***********.**** *** ******** ****** **:: **********:**********:*:****. ************:**::*. .* *:*: :. * .****: ::*.***:*::::*:::..*. ..:*.:::. ..*.::* ::..* :.:*..::..: : *:.:.. ..:.: :: : :* *: : *** *:**** . .*: ::*.: :*:* :::: : . *. * :: .:* ** :**** *:********* * * .* . .:**:* :: * *. *. *..: *:.. . ::. ::: .:: ... . . * *: :. .:.* **: :**.::: : .*: . *.**:: :* .**.....: : ** **** *: :::.. *:: ::.:.:::.:: :.:. ::.: :. ::*** :***:: : :.: * .. *.:.***.:.** * :: *: * .:: :::*:. *:*. *:.*.*.:. . .*... *:*:** . :**:**.:: :. : *:..:.:::*:* .:** *..: :.*. : :*. . *.. .: ::.* *.. *.* :.:::.. * :.:.:: *.*:...: : : :. .:. **.*...: ", "identical_positions": 248, "similar_positions": 314, "identity": "25.36%" }, { "cls_id": "homologset.agr.RGD:620317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57093-1", "uniprot_id": "PAHX_RAT", "id": "P57093-1", "name": "Phytanoyl-CoA dioxygenase, peroxisomal", "aln": "MDYTRAGARLQVLLGHLGRPSALQIVAHPVSGPASPANFCPEQFQYTLDNNVLSLEQRKFYEENGFLVIKNLVSDDDIQRFRAEFERICRKEVKPPGMTVMKDVAIAKQGYAPSERVVTKIQDFQQNEELFRYCALPQIVKYVECFTGPNIMAMHTMLINKPPDSGKKTSRHPLHQDLHFFPFRPSNLIVCAWTAMEHIDRNNGCLVVLPGTHKGPLKPHDYPKWEGGVNKMYHGIQDYDPDSPRVHLVMEKGDTVFFHPLLIHGSGRNRTQGFRKAISCHYGSSDCKYISVKGTSQENIAREVIEIAEKRYGVQGALDFEDTWKFRCRLVKGERINL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35386-1", "uniprot_id": "PAHX_MOUSE", "id": "O35386-1", "name": "Phytanoyl-CoA dioxygenase, peroxisomal", "aln": "MNLTRAGARLQVLLGHLGRPSAPTIVAQPVSGLASPASFQPEQFQYTLDNNVLTLEQRKFYEENGFLVIKNLVSDDDIQRFRAEFERICREEVKPPGIVIMRDVALAKQDYMPSDRMVSKIQDFQEDEELFRYCLLPEILKYVECFTGPNIMALHGMLINKPPDVGKKTSRHPLHQDLHYFPFRPSNLIVCAWTAMEHIDRNNGCLVVLPGTHKGTLKPHDYPKWEGGVNKMYHGIQDYDPNSPRVHLVMEKGDTVFFHPLLIHGSGRNKTQGFRKAISCHFGSSDCQCIDVSGTSQENIAREVVEMAEKKYGFQGVMDFKDTWIFRSRLVKGERINI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14832-1", "uniprot_id": "PAHX_HUMAN", "id": "O14832-1", "name": "Phytanoyl-CoA dioxygenase, peroxisomal", "aln": "MEQLRAAARLQIVLGHLGRPSAGAVVAHPTSGTISSASFHPQQFQYTLDNNVLTLEQRKFYEENGFLVIKNLVPDADIQRFRNEFEKICRKEVKPLGLTVMRDVTISKSEYAPSEKMITKVQDFQEDKELFRYCTLPEILKYVECFTGPNIMAMHTMLINKPPDSGKKTSRHPLHQDLHYFPFRPSDLIVCAWTAMEHISRNNGCLVVLPGTHKGSLKPHDYPKWEGGVNKMFHGIQDYEENKARVHLVMEKGDTVFFHPLLIHGSGQNKTQGFRKAISCHFASADCHYIDVKGTSQENIEKEVVGIAHKFFGAENSVNLKDIWMFRARLVKGERTNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N5G7-1", "uniprot_id": "A0A8M1N5G7_DANRE", "id": "A0A8M1N5G7-1", "name": "Phytanoyl-CoA dioxygenase, peroxisomal", "aln": "--MSRAADRLKVVLNHLDR-SHDAVRASFTSAQNVSYHHHPQSLQYTFDTDVLTQEQIIAYEENGFILIRNLVSEEDIDRFKNEFERICKREVKVPGLTVMKDVSIAKSEFVEGEKAVTKLQDYQEDPELFRYCVLPQILKYVECFTGPNIMAMHTMLINKPPDTGKKTSRHPMHQDLHYFPFRPADRIVCSWTAMEKVHRENGCLVVLPGSHRGSLQEHDYPEWEGGVNKMYHGVRNYDPNHPRVHLEMEKGDTVFFHPLLIHGSGMNQTNGFRKAISCHYASGDCYYIDVNGTTQENISNEVKDLASRKFGADDSVTFADTWAIRGRLVQGDRISM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. **:::*.**.* * : * .*. . . *:.:***:*.:**: ** ******::*:***.: **:**: ***:**:.*** *:.:*:**:::*. : .:: ::*:**:*:: ****** **:*:*************:* ******** ********:*****:*****:: ***:*****:: *:*********:*:*.*: ****:********:**:::*: : .**** ****************** *:*:*********:.*.** *.*.**:**** .** :* : :* :. : : * * :* ***:*:* .:", "identical_positions": 192, "similar_positions": 90, "identity": "56.8%" }, { "cls_id": "homologset.agr.RGD:620318", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10643-1", "uniprot_id": "CO7_HUMAN", "id": "P10643-1", "name": "Complement component C7", "aln": "MKVISLFILVGFIGEFQSFSSASSPVNCQWDFYAPWSECNGCTKTQTRRRSVAVYGQYGGQPCVGNAFETQSCEPTRGCPTEEGCGERFRCFSGQCISKSLVCNGDSDCDEDSADEDRCEDSERRPSCDIDKPPPNIELTGNGYNELTGQFRNRVINTKSFGGQCRKVFSGDGKDFYRLSGNVLSYTFQVKINNDFNYEFYNSTWSYVKHTSTEHTSSSRKRSFFRSSSSSSRSYTSHTNEIHKGKSYQLLVVENTVEVAQFINNNPEFLQLAEPFWKELSHLPSLYDYSAYRRLIDQYGTHYLQSGSLGGEYRVLFYVDSEKLKQNDFNSVEEKKCKSSGWHFVVKFSSHG-CKELENALKAASGTQNNVLRGEPFIRGGGAGFISGLSYLELDNPAGNKRRYSAWAESVTNLPQVIKQKLTPLYELVKEVPCASVKKLYLKWALEEYLDEFDPCHCRPCQNGGLATVEGTHCLCHCKPYTFGAACEQGVLVGNQAGGVDGGWSCWSSWSPCVQGKKTRSRECNNPPPSGGGRSCVGETTESTQCEDEELEHLRLLEPHCFPLSLVPTEFCPSPPALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKIACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPEMKNARCVQKEN-PLTQAVPKCQRWEKLQNSRCVCKMPYECGPSLDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGRDSCTLPASAEKACGACPLWGKCDAESSKCVCREASECEEEGFSICVEVNGKEQTMSECEAGALRCRGQSISVTSIRPCAAETQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M8W6-1", "uniprot_id": "A0ABK0M8W6_RAT", "id": "A0ABK0M8W6-1", "name": "Complement component C7", "aln": "-----------------MFPKHEG--NKLINFGGIYDRVS--NLLKTRRRSIAVYGQYGGHRCVGSAFETQSCNPERGCPTEEGCGDRFRCFSGQCISKSLVCNGDSDCEEDGADEDRCEGAESRPSCDTVKPPPNIELTGNGYNALTGQFRNRVINTKSFGGQCRKVFSGDGRDFYRLSGNILSYTFQVKIDNDFNYEFYNSSWSYVKHTSTDYTSSSSNRFLFFSSSSNRHTQSSSTKEIYMKKSYKLLVVQNTVEVAQFINNNPEFLQLAEPFWRELSHLPTLYDYSAYRRLIDQYGTHYLQSGSLGGEYRVLFYVDSGDVKHRGFGSVQEKACSSSDFKFIFVSSANQRCKELENIFKSNSGNQGRVLRGEPSVIGGGPGFVADLSFLDLDNPAGNRQRYSSWASSVTSLPQVIKQRLTPLYELVKEVPCASVKRLYLKRALEEYLDEFDPCHCRPCQNGGIASVVGTQCQCHCKPYTYGMACEQGVLVGDQAGGVDGGWSCWSSWSPCVQGKKSRSRECNNPPPRAGGKACIGETTESRQCEDQDLENLRLLEPHCFHLSLVPKGFCPSPPALKDGFVQSEGTMFPIGKNIVYACNEGYSLVGDPVARCGEDLQWLVGEMHCQKIACFLPGGMNGMRSDPQKPFYMVGEKVTLSCAGGMSLEGPSTFLCGSSLKWSPELKSAQCVQKVTSTLTPAAPACQPWEKLKNSKCVCKMPYECGSSLDVCARDERSNRILPLTICKMHVLQCQGRNYALVGKNSCTLPASTEKACGACPIWSKCDAQNSKCVCREASECQKAGYRICVEVNGKEETMSECEAGILRCRGQSISITAIKPCAQEVQ", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. .. * :* . :.. . . :*****:********: ***.*******:* **********:**********************:**.*******.:* ***** ************** ***************************:********:*********:**********:*********::**** :* :* ****. :: :* *:**: ***:****:***********************:******:************************************ .:*:..*.**:** *.**.::*:. *:: ****** :*: **.*..****** : ***.**::.**:*:*******::***:**.***.*******:*****************:**** *********************:*:* **:* *******:* *********:***********************:********** .**::*:****** ****::**:********* *****. **************.******:***:**:*******:*:*********:*************.** *:*::*.****** ******:**:*********:************:*.*:**** . .** *.* ** ****:**:**********.******:****:******:******:******:*.*::*******:********:*.****:.***********:: *: *********:******** *********:*:*:*** *.*", "identical_positions": 638, "similar_positions": 132, "identity": "75.5%" }, { "cls_id": "homologset.agr.RGD:620319", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62930-1", "uniprot_id": "CO9_RAT", "id": "Q62930-1", "name": "Complement component C9", "aln": "MASGVTITLAIAIFALEIN-AQAPEPTPREEPSA-DALLPIDCRMSTWSQWSQCDPCLKQRFRSRSIEVFGQFQGKSCADALGDRQHCEPTQECEEVQENCGNDFQCETGRCIKRKLLCNGDNDCGDFSDESDCESDPRLPCRDRVVEESELGRTAGYGINILGMDPLGTPFDNEFYNGLCDRVRDGNTLTYYRKPWNVAFLAYETKADKNFRTENYEEQFEMFKTIVRDRTTSFNANLALKFTITEAPIKKVGVDEVSPEKNSSKPKDSSVDFQFSYFKKENFQRLSSYLSQTKKMFLHVKGMIQLGRFVMRNRGVMLTTTFLDDVKALPVSYEKGEYFGFLETYGTHYSSSGSLGGLYELIYVLDKASMKEKGVELSDVKRCLGFNLDVSLYTPLQTALEGPSLTANVNHSDCLKTGDGKVVNISRDHIIDDVISFIRGGTRKQAVLLKEKLLRGAKTIDVNDFINWASSLDDAPALISQKLSPIYNLIPLTMKDAYAKKQNMEKAIEDYVNEFSARKCYPCQNGGTAILLDGQCMCSCTIKFKGIACEISKQR--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06683-1", "uniprot_id": "CO9_MOUSE", "id": "P06683-1", "name": "Complement component C9", "aln": "MASGMAITLALAIFALGVN-AQMPIPVSREEQEQ-HYPIPIDCRMSPWSNWSECDPCLKQRFRSRSILAFGQFNGKSCVDVLGDRQGCEPTQECEEIQENCGNDFQCETGRCIKRRLLCNGDNDCGDYSDENDCDDDPRTPCRDRVAEESELGLTAGYGINILGMEPLRTPFDNEFYNGLCDRVRDEK--TYYRKPWNVVSLIYETKADKSFRTENYDEHLEVFKAINREKTSNFNADFALKFSATEVPEK--GAGEVSPAEHSSKPTNISAKFKFSYFMGKNFRRLSSYFSQSKKMFVHLRGVVQLGRFVMRNRDVVLRSTFLDDVKALPTSYEKGEYFGFLETYGTHYSTSGSLGGQYEIVYVLDKASMKEKGVDLNDVKHCLGFNMD--LRIPLQDDLKDASVTASVNADGCIKTDNGKTVNITRDNIIDDVISFIRGGTREQAILLKEKILRGDKTFDKTDFANWASSLANAPALISQRMSPIYNLIPLKIKDAYIKKQNLEKAVEDYIDEFSTKRCYPCLNGGTIILLDGQCLCSCPMMFRGMACEIHQKI--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02748-1", "uniprot_id": "CO9_HUMAN", "id": "P02748-1", "name": "Complement component C9", "aln": "MSACRSFAVAICILEISILTAQYTTSYDPELTESSGSASHIDCRMSPWSEWSQCDPCLRQMFRSRSIEVFGQFNGKRCTDAVGDRRQCVPTEPCEDAEDDCGNDFQCSTGRCIKMRLRCNGDNDCGDFSDEDDCESEPRPPCRDRVVEESELARTAGYGINILGMDPLSTPFDNEFYNGLCNRDRDGNTLTYYRRPWNVASLIYETKGEKNFRTEHYEEQIEAFKSIIQEKTSNFNAAISLKFTPTETNKA----EQCCEETASSISLHGKGSFRFSYSKNETYQLFLSYSSKKEKMFLHVKGEIHLGRFVMRNRDVVLTTTFVDDIKALPTTYEKGEYFAFLETYGTHYSSSGSLGGLYELIYVLDKASMKRKGVELKDIKRCLGYHLD------VSLAFSEISVGAEFNKDDCVKRGEGRAVNITSENLIDDVVSLIRGGTRKYAFELKEKLLRG-TVIDVTDFVNWASSINDAPVLISQKLSPIYNLVPVKMKNAHLKKQNLERAIEDYINEFSVRKCHTCQNGGTVILMDGKCLCACPFKFEGIACEISKQKISEGLPALEFPNEK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: ::::*:.*: : : ** . . * . ******.**:**:*****:* ****** .****:** *.*.:***: * **: **: :::*******.****** :* *********:***.**:.:** ******.*****. ***********:** ************:* ** : ****:****. * ****.:*.****:*:*::* **:* :::*:.*** ::***: **. : . ** . . . .*:*** :.:: : ** *:.:***:*::* ::*********.*:* :**:**:****.:*******.**********:****** **::*********.***:*.*:*:***:::* :. :. *: *..* ..*:* .:*:.***: :::****:*:******: *. ****:*** ..:* .** *****: :**.****::******:*:.:*:*: ****:*:*:***::***.::*:.* **** **:**:*:*:*.: *.*:**** :: ", "identical_positions": 305, "similar_positions": 157, "identity": "53.51%" }, { "cls_id": "homologset.agr.RGD:62032", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63180-1", "uniprot_id": "ADAM7_RAT", "id": "Q63180-1", "name": "Disintegrin and metalloproteinase domain-containing protein 7", "aln": "MFPTGIFLMSVLISQMQGRGIVGVEGQELVHPKKLSLLQKRDLERIHDSDTPEEYEEELLYEIKLGRKTLTLHLLKAREFLALNYSETYYNIKREMVTRHPQILDHCFYQGSIIHEFDSAASISTCNGLRGFFRVNDQRYLIEPVKYSDEGDHLVFKYNVKAPYATNYSCEGLNFTKKSTLIDAKIIEEHKVEDYHKEKFIELFVVADEFVYRRNSKPQNKLRKRIWGMVNFVNMIYKALNIRVTLTGMEIWSAGDEIEIVSNLESTLLHFSTWQETVLKKRKDFDHVILLSGKWLYTSMQGIAYPGGICQTLRSCSVVKDLLPDVNIIGNRMAHQLGHSLGMRHDDFPCTCPLGKCVMG-AGSIPAIKFSKCSQTQYQQFLKNQKPACILNNPLPEEFNDYPFCGNKKVDEGEECDCGPVQECTNPCCDAHKCVLKPGFTCVEGECCESCQMKKEGVICRPAKNECDISEVCTGYSPECPKDESQANGFPCKNGEGYCFMGLCPTRDDQCAELFSGGAEESHSLCYRMNQKGNRFGYCKNKDNTFVPCEEKDLKCGKIYCTGGRRSAHLGEDKTYNLKNVKQNISIKCKTMFLYHNSRDMGLVNSGTKCGEGMVCSNGECIEMEKAYNSTICSSLCDENDVDDNEPDCQCEEGPIITEWGEALNLTSVSIMVVVLVMVIIGVGLVILLIRYQKCIKMKQVQSSSREIRGIENKVYFPDEHQTRSEPIFTDIYPLHNTAESLERVPSTFSSPHYITLKSVSKDPRGIADPKQNDNMNLNLDSQSDCTRLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35227-1", "uniprot_id": "ADAM7_MOUSE", "id": "O35227-1", "name": "Disintegrin and metalloproteinase domain-containing protein 7", "aln": "MLTTGIFWMTVLISHIQERGIVGVEGQELVHPKKLPLLHKRDLERIHDSDIPEEYEEELLYEIKLGKKTLILHLLKAREFLSSNYSETYYNVKREVFTKHPQILDHCFYQGSIIHEFDSAASISTCNGLRGFFRVNDQRYLIEPVKYSDDGEHLVYKYNVKAPYATNHSCVGLNFTKKSALIDVENIEEHNAEDHHKEKFIELFVVADEYVYRRNNKPQNKLRKRIWGMVNFVNMIYKTLNIHVTLAGFEIWSAGDKIEIVSNLESTLLHFSTWQETVLKKRKDFDHVILLSGKWLYTSMQGIAYPGGICQILRSCSVVKDLLPDVNIIGNRMAHQLGHSLGMQHDGFPCTCPLGKCVMG-DGSIPAIKFSKCSQTQYQQFLQDQKPACILNNPFPEEFNDYPFCGNKKVDEGEECDCGPVQECTNPCCDAHKCVLKPGFTCVEGECCESCQMKKEGAVCRLAKNECDISEVCTGYSPECPKDEFQANGFPCRNGEGYCFMGLCPTRNEQCSELFIGGAEESHSLCYRMNKKGNRFGYCKNKGNTFVPCEEKDLKCGKIYCSGGRPSSRLGEDKAYNLKNVKQNVTIKCRTMFLHHNSRDMGLVNSGTKCGDGMVCSNGECIEMEKAYNSTICSSPCDENDVDDNEPECQCEEGSIITEWGEALNLTSVSIMVIVLVMVIIGVGLVILLIRYQKCIKMKQVQSSPREIRGVENKGYFPEEHQTRSEPILTDIHPLHTTAESLERVPSSFSSPHYITLKSVSKDSRGIADPKQTDNVNLNLDTQSGCERLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2U9-1", "uniprot_id": "ADAM7_HUMAN", "id": "Q9H2U9-1", "name": "Disintegrin and metalloproteinase domain-containing protein 7", "aln": "MLPGCIFLMILLIPQVKEKFILGVEGQQLVRPKKLPLIQKRDTGHTHDDDILKTYEEELLYEIKLNRKTLVLHLLRSREFLGSNYSETFYSMKGEAFTRHPQIMDHCFYQGSIVHEYDSAASISTCNGLRGFFRINDQRYLIEPVKYSDEGEHLVFKYNLRVPYGANYSCTELNFTRKTVPGDNESEEDSKIKGIHDEKYVELFIVADDTVYRRNGHPHNKLRNRIWGMVNFVNMIYKTLNIHVTLVGIEIWTHEDKIELYSNIETTLLRFSFWQEKILKTRKDFDHVVLLSGKWLYSHVQGISYPGGMCLPYYSTSIIKDLLPDTNIIANRMAHQLGHNLGMQHDEFPCTCPSGKCVMDSDGSIPALKFSKCSQNQYHQYLKDYKPTCMLNIPFPYNFHDFQFCGNKKLDEGEECDCGPAQECTNPCCDAHTCVLKPGFTCAEGECCESCQIKKAGSICRPAKDECDFPEMCTGHSPACPKDQFRVNGFPCKNSEGYCFMGKCPTREDQCSELFDDEAIESHDICYKMNTKGNKFGYCKNKENRFLPCEEKDVRCGKIYCTGGELSSLLGEDKTYHLKDPQKNATVKCKTIFLYHDSTDIGLVASGTKCGEGMVCNNGECLNMEKVYISTNCPSQCNENPVDGHGLQCHCEEGQAPVACEETLHVTNITILVVVLVLVIVGIGVLILLVRYRKCIKLKQVQSPPTETLGVENKGYFGDEQQIRTEPILPEIHFLN---------------------KPASKDSRGIADPNQSAK---------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. ** * :**.::: : *:*****:**:****.*::*** : **.* : ***********.:*** ****::****. *****:*.:* * .*:****:*********:**:*****************:**************:*:***:***::.**.:*:** ****:*:. * : *: : :. *.**::***:***: *****.:*:****:**************:***:***.*:***: *:**: **:*:***:** ***.:**.*******:********: :***:****:* * *::******.***.*********.***:** ****** *****. *****:*******.**:*:*:: **:*:** *:* :*:*: ******:**********.***********.*********.*********:** * :** **:***:.*:***:** ****: :.*****:*.******* ****::**:*** . * ***.:**:** ***:******* * *:******::******:**. *: *****:*:**: ::* ::**:*:**:*:* *:*** ******:****.****::***.* ** *.* *:** **.: :*:**** . *:*::*.::*:*:***:**:*:*::***:**:****:*****.. * *:*** ** :*:* *:***:.:*: *: *..***.******:*. : ", "identical_positions": 490, "similar_positions": 181, "identity": "62.03%" }, { "cls_id": "homologset.agr.RGD:620320", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88998-1", "uniprot_id": "NOE1_MOUSE", "id": "O88998-1", "name": "Noelin", "aln": "MSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTRLSAASGGTLDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLETKFKQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERLRACMQKLACGKLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTEAILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDENGLWAVYATNQNAGNIVISKLDPVSLQILQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQTLYNVTLFHVIRSDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62609-1", "uniprot_id": "NOE1_RAT", "id": "Q62609-1", "name": "Noelin", "aln": "MSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTRLSAASGGTLDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFRQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERLRACMQKLACGKLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDENGLWAVYATNQNAGNIVISKLDPVSLQILQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQTLYNVTLFHVIRSDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99784-1", "uniprot_id": "NOE1_HUMAN", "id": "Q99784-1", "name": "Noelin", "aln": "MSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTKLSAAGGGTLDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERLRACMQKLACGKLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDESGLWAVYATNQNAGNIVVSRLDPVSLQTLQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQILYNVTLFHVIRSDEL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********************************:****.********************************************************************************************:**:***********************************************************************************************************************************************************************************************:********************************.****************:*:******* ******************************************************************************** ***************", "identical_positions": 475, "similar_positions": 8, "identity": "97.94%" }, { "cls_id": "homologset.agr.RGD:620321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Q3-1", "uniprot_id": "HYAL2_RAT", "id": "Q9Z2Q3-1", "name": "Hyaluronidase-2", "aln": "------------------------------MRAGLGPIITLALVLEVAWASELKPTAPPIFTGRPFVVAWNVPTQECAPRHKVPLDLRAFDVEATPNEGFFNQNITTFYYDRLGLYPRFDAAGMSVHGGVPQNGSLCAHLPMLKEAVERYIQTQEPAGLAVIDWEEWRPVWVRNWQEKDVYRQSSRQLVASRHPDWPSDRIVKQAQYEFEFAARQFMLNTLRYVKAVRPQHLWGFYLFPDCYNHDYVQNWDSYTGRCPDVEVAQNDQLAWLWAENTALFPSVYLDKTLASSKHSRNFVSFRVQEALRVAHTHHANHALPVYVFTRPTYTR--------RLTELNQMDLISTIGESAALGSAGVIFWGDSVYASSMENCQNLKKYLTQTLVPYIVNVSWATQYCSWTQCHGHGRCVRRNPSASTFLHLSPSSFRLVPGRTPSEPQLRPEGELSEDDLSYLQMHFRCHCYLGWGGEQCQWNHKRAAGDASRAWAGAHLASLLGLVAMTLTWTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35632-1", "uniprot_id": "HYAL2_MOUSE", "id": "O35632-1", "name": "Hyaluronidase-2", "aln": "------------------------------MRAGLGPIITLALVLEVAWAGELKPTAPPIFTGRPFVVAWNVPTQECAPRHKVPLDLRAFDVKATPNEGFFNQNITTFYYDRLGLYPRFDAAGTSVHGGVPQNGSLCAHLPMLKESVERYIQTQEPGGLAVIDWEEWRPVWVRNWQEKDVYRQSSRQLVASRHPDWPSDRVMKQAQYEFEFAARQFMLNTLRYVKAVRPQHLWGFYLFPDCYNHDYVQNWESYTGRCPDVEVARNDQLAWLWAESTALFPSVYLDETLASSVHSRNFVSFRVREALRVAHTHHANHALPVYVFTRPTYTR--------GLTGLSQVDLISTIGESAALGSAGVIFWGDSEDASSMETCQYLKNYLTQLLVPYIVNVSWATQYCSWTQCHGHGRCVRRNPSANTFLHLNASSFRLVPGHTPSEPQLRPEGQLSEADLNYLQKHFRCQCYLGWGGEQCQRNYKGAAGNASRAWAGSHLTSLLGLVAVALTWTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12891-1", "uniprot_id": "HYAL2_HUMAN", "id": "Q12891-1", "name": "Hyaluronidase-2", "aln": "------------------------------MRAGPGPTVTLALVLAVSWAMELKPTAPPIFTGRPFVVAWDVPTQDCGPRLKVPLDLNAFDVQASPNEGFVNQNITIFYRDRLGLYPRFDSAGRSVHGGVPQNVSLWAHRKMLQKRVEHYIRTQESAGLAVIDWEDWRPVWVRNWQDKDVYRRLSRQLVASRHPDWPPDRIVKQAQYEFEFAAQQFMLETLRYVKAVRPRHLWGFYLFPDCYNHDYVQNWESYTGRCPDVEVARNDQLAWLWAESTALFPSVYLDETLASSRHGRNFVSFRVQEALRVARTHHANHALPVYVFTRPTYSR--------RLTGLSEMDLISTIGESAALGAAGVILWGDAGYTTSTETCQYLKDYLTRLLVPYVVNVSWATQYCSRAQCHGHGRCVRRNPSASTFLHLSTNSFRLVPGHAPGEPQLRPVGELSWADIDHLQTHFRCQCYLGWSGEQCQWDHRQAAGGASEAWAGSHLTSLLALAALAFTWTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TES9-1", "uniprot_id": "A0A8N7TES9_DANRE", "id": "A0A8N7TES9-1", "name": "Hyaluronidase", "aln": "MSERTGVLNGFSQIRSEMKNITHLSGTTRTQRASWLQVLLLMLFWTCLKAQQLKNTRWPLYSGKPLLLAWNAPTEDCRPRHDVTFQLDQFQIVASPNEGFTKQNLTIFYQDRLGLYPYFKPDSTPVYGGLPQAASLTQHLEKMPDGLKKYIKDQAVKGLAVIDWEEWRPLWIRNWGPKLIYRDRSQRLVAEKNPTWPLDQVTKVAQQEFELSARKFMLETLRLAKSLRPQQLWGYYLFPDCYNHNYQTNLQNYTGQCPDIEVSRNNELKWLWTESTALYPSVYMGKILKDNPKGRQFVRNRVKEGMRLASVGDG-SARPVFVYTRPTYLTNMTSSNPAELLLLTEMDLVSTIGESVALGVAGVILWGDSTYASSQATCSSLNEYLRGPLGRYLLNVTSAAEQCSRNLCGFRGRCLRKQPNTDTYLHLSASTHRIER----QANTLKLTGQMSEEELGRLRDDFQCQCYNGYSGDDCSIKD-NGNRAAALWTSALQYWVLPLILMGFLH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3ATS4-1", "uniprot_id": "A0A8M3ATS4_DANRE", "id": "A0A8M3ATS4-1", "name": "Hyaluronidase", "aln": "MSK---------PLSWRTKVMAHWI------RLYWRICLLVHLTL----AEDLKPTRWPLYPQKPLVLVWNAPTEDCRPRHKVHFQLDQFQIVASPNQGFTKQNLTIFYKDRLGLYPHY-EDGTAVNGGLPQIASLTQHLEKMPEGIEKYIRDPLAKGLAVIDWEEWRPLWIRNWEAKEIYKRQSKHLVSQKNPDWTSSQISKTAQMEFELSSRKFMQETLRLAKSLRPHQLWGFYLFPDCYNHDYRNSLESYTGRCPDVELVRNDLLKWLWTESTALFPSIYMGSVLRSTSFGRQFVRNRVKEGMRLASVGEG-LARPVFVYSRPTYAN--------ELEVLTETDLVSTIGESVALGAAGIVLWGDAAYASSNASCSSINQYLRGPLGQYLLNVSTAAEQCSGFLCSSHGRCLRRHADTDTYLHLDPKTHTIVG----QGSEMRVRGDLSVEEHRRMTKDFQCQCFSGYQGERCDLEDPLQQRGHGNTLKALWIYPLSPLLLHLLT---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : * * :** * *::. :*:::.*:.**::* ** .* ::* *:: *:**:** :**:* ** ******* : . .* **:** ** * : . :::**: ********:***:*:*** * :*: *::**:.::* *. .:: * ** ***:::::** :*** .*::**::***:*********:* . :.***:***:*: :*: * ***:*.***:**:*:.. * .. .*:** **:*.:*:* . .. * **:*::**** * *.: **:******.*** **:::***: ::* .*. ::.** * *::**: *:: ** * :***:*::..:.*:***...:. : :: *::* : : .*:*:*: *: *: *. . . . * : : ", "identical_positions": 176, "similar_positions": 144, "identity": "34.44%" }, { "cls_id": "homologset.agr.RGD:620322", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925N4-1", "uniprot_id": "CLD16_MOUSE", "id": "Q925N4-1", "name": "Claudin-16", "aln": "MKDLLQYAACFLAIFSTGFLIVATWTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSIYAEHPLKLVVTRALMITADILAGFGFITLLLGLDCVKFLPDDPQIKVRLCFVAGTTLLIAGTPGIIGSVWYAVDVYVERSSLVLHNIFLGIQYKFGWSCWLGMAGSLGCFLAGALLTCCLYLFKDVGPERNYPYAMRKPYSTAGVSMAKSYKAPRTETAKMYAVDTRV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Y55-1", "uniprot_id": "CLD16_RAT", "id": "Q91Y55-1", "name": "Claudin-16", "aln": "MKDLLQYAACFLAIFSTGFLIVATRTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSIYAEHPLKLVVTRALMITADILAGFGFITLLLGLDCVKFLPDEPHIKVRLCFVAGTVLLIAGTPGIIGSVWYAVDVYVERSSLVLHNIFLGIQYKFGWSCWLGMAGSLGCFLAGALLTCCLYLFKDVGPERNYPYAMRKPYSTAGVSMAKSYKAPRTETAKMYAVDTRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5I7-1", "uniprot_id": "CLD16_HUMAN", "id": "Q9Y5I7-1", "name": "Claudin-16", "aln": "MRDLLQYIACFFAFFSAGFLIVATWTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSILAEHPLKLVVTRALMITADILAGFGFLTLLLGLDCVKFLPDEPYIKVRICFVAGATLLIAGTPGIIGSVWYAVDVYVERSTLVLHNIFLGIQYKFGWSCWLGMAGSLGCFLAGAVLTCCLYLFKDVGPERNYPYSLRKAYSAAGVSMAKSYSAPRTETAKMYAVDTRV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:***** ***:*:**:******* ****************************************** *************************:**************:* ****:*****:.************************:*********************************:*******************::**.**:*********.****************", "identical_positions": 215, "similar_positions": 16, "identity": "91.49%" }, { "cls_id": "homologset.agr.RGD:620323", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08707-1", "uniprot_id": "ACKR2_MOUSE", "id": "O08707-1", "name": "Atypical chemokine receptor 2", "aln": "MPTVASPLPLTTVGSEN-SSSIYDYDYLDDMTILVCRKDEVLSFGRVFLPVVYSLIFVLGLAGNLLLLVVLLHSAP-RRRTMELYLLNLAVSNLLFVVTMPFWAISVAWHWVFGSFLCKVISTLYSINFYCGIFFITCMSLDKYLEIVHAQPLHRPKAQFRNLLLIVMVWITSLAISVPEMVFVQIHQTLDGVWHCYADFGGHATIWKLYLRFQLNLLGFLLPLLAMIFFYSRIGCVLVRLRPPGQGRALRMAAALVIVFFMLWFPYNLTLFLHSLLDLHVFGNCEISHRLDYTLQVTESLAFSHCCFTPVLYAFCSHRFRRYLKAFLSVMLRWHQAPG---TPSSNHSESSRVTAQEDVVSMNDLGERQSEDSLNKGEMGNT--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O09027-1", "uniprot_id": "ACKR2_RAT", "id": "O09027-1", "name": "Atypical chemokine receptor 2", "aln": "MPTIASPLPLATTGPEN-GSSIYDYDYLDDVTVLVCSKDEVLSFGRVFLPVVYSLIFVLGLAGNLLLLVVLLHSVPQRRRMIELYLLNLAVSNLLFVVTMPFWAISVAWHWVFGSFLCKVVSTLYSINFYCGIFFITCMSLDKYLEIVHAQPLHRPKTRFRNLLLIVMVWITALAVSVPEMVFVKVHQTLDGVWHCYADFGGHATIWKLYLRFQMNLLGFLFPLLAMIFFYSRIGCVLVRLRPPGQGRALRMAAALVVVFFLLWFPYNLTLFLHSLLDLHVFGNCKISHRLDYMLQVTESLAFSHCCFTPVLYAFSSHSFRQYLKAVLSVVLRRHQAPGTAHAPPCSHSESSRVTAQEDVVSMNDLGERQADISLNKGEIGNN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00590-1", "uniprot_id": "ACKR2_HUMAN", "id": "O00590-1", "name": "Atypical chemokine receptor 2", "aln": "MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLGLSGNLLLLMVLLRYVP-RRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKMVSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPDMVFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRLRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTESIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEMTGMNDLGERQSENYPNKEDVGNKSA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: *** **:* ..:. .**:* *****:::.::* ** *:***:*****.*********:******:***: .* *** :*:******:*****:**:***.***************::****:****.*****:*************** ** ::: :.*** .:** .:**:*:*:****: *:. .***:*:******.*****:**** ******:*********************.******::*****:.**:************:****:*****::*::*** ******:** ****:*:****.** **:****.*:.:* * *** :. .. **** :****::..********:: ** ::**. ", "identical_positions": 260, "similar_positions": 89, "identity": "67.53%" }, { "cls_id": "homologset.agr.RGD:620324", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31430-1", "uniprot_id": "DPEP1_RAT", "id": "P31430-1", "name": "Dipeptidase 1", "aln": "------------------------MLIIWWFWSLLA---------------ICAS-----------------DSFRNQAEN--------IMRTTPVIDGHNDLPWQMLT--LFNNQLR-------------KSEANLSALAETHTNIPKLRAGFVGGQFWSAYMPCDTQNKDAVKRILEQIDVIHRMCQLYPETFECVTNSSDILQAFRRGKVASLIGVEGGHLIDSSLGVLRTLYHLGMRYLTLT-HNCNTPWADNWLVDKGDDEAE--SQGLSPFGKLVLNEMNRLGVMIDLSHVSVATMKDALQLSKAPVIFSHSSAYSVCPHR--RNVPDDVLQLVKSTNSLVMVNFYNQFVSCSDSATLSQVADHLDHIKKVAGAGAVGLGGDYDGVTNLPVGLEDVSKYPDLIAELLRRN-WTETEVRGLLAENLLRVFSAVELVSNIMQ----VPEEETIPVEKLDGSCRTFYGHSR-APSIHLQIGALLASLASLVFSLHLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31428-1", "uniprot_id": "DPEP1_MOUSE", "id": "P31428-1", "name": "Dipeptidase 1", "aln": "------------------------MVIIWWFWSLLA---------------ICAS-----------------DSFRDQAVA--------IMRTTPVIDGHNDLPWQLLN--LFNNQLL-------------RPDADLNKLAQTHTNIPKLKAGFVGGQFWSAYMPCDTQNKDAVKRILEQMDVIHRMCQLYPETFMCVTNSSDILQAFRRGKVASLIGVEGGHLIDSSLGVLRTLYHLGMRYLTLT-HNCNTPWADNWLVDRGDDEAE--SHGLSPFGKRLLNEMNRLGVMIDLSHVSVATMKDALQISRAPVIFSHSSAYSLCPHR--RNVPDDVLQLVKNTSSLVMVNFFSNFVSCSDSATLPQVADHLDHIKKVAGAGAVGLGGDYDGVTMLPVGLEDVSKYPDLIAELLRRN-WTETEVRGLLADNLIRVFSEVELVSNNMQ----SPEEVPITLKELDGSCRTYYGYSQ-AHSIHLQTGALVASLASLLFRLHLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16444-1", "uniprot_id": "DPEP1_HUMAN", "id": "P16444-1", "name": "Dipeptidase 1", "aln": "------------------------MWSGWWLWPLVA---------------VCTA-----------------DFFRDEAER--------IMRDSPVIDGHNDLPWQLLD--MFNNRLQ-------------DERANLTTLAGTHTNIPKLRAGFVGGQFWSVYTPCDTQNKDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHSIDSSLGVLRALYQLGMRYLTLT-HSCNTPWADNWLVDTGDSEPQ--SQGLSPFGQRVVKELNRLGVLIDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASR--RNVPDDVLRLVKQTDSLVMVNFYNNYISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLRRN-WTEAEVKGALADNLLRVFEAVEQASNLTQ----APEEEPIPLDQLGGSCRTHYGYSSGASSLHRHWGLLLASLAPLVLCLSLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VBG1-1", "uniprot_id": "Q9VBG1_DROME", "id": "Q9VBG1-1", "name": "Dipeptidase", "aln": "---------MKSRKLPKGFVLCGLNCLTFVYFPLVLP------------ILRCSAGAASSASGGGSKTADDFDFRMQRVRN--------VLKEVPLIDGHNDLPWNIRK--FLKNQLKDFH-----FGGDLRELAPWSSSAWSHTDLRRLKEGMVSAQFWSAYAPCSSQHLDAVQLTLEQIDLIRRLVQLYPHHMALVTTASGIEQTHRTGKIASLIGVEGGHAIGTSLSVLRMFYQLGARYLTLT-HTCNTPWADCCKVDEPGKYPH--IGGLSQFGKLVVKEMNRLGMIVDLSHVSVPTMLDALAASRAPLIFSHSSAHAICNSS--RNVPDHVLQRIAINGGLVMVAFYPHFVSCSGQATLHDVVAHINHIREVAGIDHVGIGAGYDGVNLVPKGLEDVSKYPHLFAALLESDKWSEEDIAKLAGRNLIRVFKEVEAVRDQMELLRVAPIDQSIPAEDIMG--RSYCRYQGPRT-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPG0-1", "uniprot_id": "Q9VPG0_DROME", "id": "Q9VPG0-1", "name": "Dipeptidase", "aln": "MNPVPSREFLEVHPLHQHQPHCKQQCFVFTEIADIELPAEITKFGGGNEKIRCSNGGIPTYSSKKDSCSESSAERPERSRGRKILLGVGVVLVCIAMAGGIPLALQLRSSSLLEARLAFIRRLLTESPLIEGSWKPPSTMSLNSSNLFEVRQNHIGAVLWPIAVPCGAQYLDAVQLTLEGIDRAKRITAAT-DSMHIVESADEMEQTHIRGEVAVLMGISGGHALGTSTAVLRSIYLLGARFVSITSLECTTPWAAAAIRRPDYLVEENVTNSFNEFGQTMLFEMNRLGMLVEISMLSEAAMLAVLKTAKAPVLLTNATPLSMCNSSNIASIPDHVLSLLPENGGVILLNLER---CGDRTLGVREAITAINYVRKVAGVDHIGLGG-------------APKSYALLLAELARDRVWGNAAIKKLVGGNVMRILREIETLKNRLP-----LYEEWIPHESIES--NSYCRYPES-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : *: :. :: : * *. :: ::: :* . : . ::: .:: . :.. :*. **.:* ***: ** :* :*: . : * .: : *:. *::* *:*:.*** :.:* .*** :* ** *::::* *.**** . .:. **: :: *:****:::::: :* .:* .* ::**:::::::. ::* .:**.** : ...:::: : . : :. ::::::*** :*:*. ..*. *:* * . * : : . *::*:: :* : : *. ..: . .:. : ", "identical_positions": 69, "similar_positions": 138, "identity": "13.8%" }, { "cls_id": "homologset.agr.RGD:620325", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29121-1", "uniprot_id": "PCSK4_MOUSE", "id": "P29121-1", "name": "Proprotein convertase subtilisin/kexin type 4", "aln": "----------------------------------------------------------------------------------------------------------------MRPSQTELWLGLTLTLALL------------------AVRWASAQAP----------------------------------------------------------------------IYVSSWAVRVTKG-YQEAERLARKFGFVNLG-QIFPDDQYFHLRHRGVAQQSLTPHWGHRLRLKKD-PKVRWFEQQTLRRRVKRSLVVP------------------TDPWFSKQWYMNKE--IQQDLNILKAWNQGLTGRGVVISILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATANNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRVPWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDLQHLVVRASRPAQLQAE-DWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPTKPQKKCAIRVVHT-PTPILPRMLVPKNVTACSDGSRRRLIRSLEHVQVQLSLSYSRRGDLEIFLTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLENKGYYFNTGTLYYYTLLLYGTAEDMT-------ARPQAPQVTSRARACVQR----------------------------------------------------DTEGLCQESHSPLSILAGLCLIS--------------------------------------------SQQWWWLYS---------------HPQQPVTEGQASCHP--------------PVTPAAAA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q78EH2-1", "uniprot_id": "PCSK4_RAT", "id": "Q78EH2-1", "name": "Proprotein convertase subtilisin/kexin type 4", "aln": "----------------------------------------------------------------------------------------------------------------MRPSQTALWLGLVLSLALL------------------AVGWASARPP----------------------------------------------------------------------IYVSSWAVRVTKG-YQEAERLARKFGFVNLG-QIFPDDQYFHLRHRGVAQQSLTPHWGHRLRLKKE-PKVRWFEQQTLRRRVKRSLVVP------------------TDPWFSKQWYMNKE--IEQDLNILKVWNQGLTGRGVVVSILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATANNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRVPWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDLQHLVVRASRPAQLQAE-DWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPTKPQKKCTIRVVHT-PTPILPRMLVPKNVTVCCDGSRRRLIRSLEHVQVQLSLSYSRRGDLEIFLTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLENKGYYYNTGTLYYCTLLLYGTAEDMT-------ARPQTP----------------------------------------------------------------------QESHCPLSIVAELCLIS--------------------------------------------SKQWWWLYS---------------HTQQPVTKGQDSCHP--------------PTTPARQLDQRLHCLFPAPHA-------------------GSASEPLQGLSP---------LAAILAISLG-PWCCPC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UW60-1", "uniprot_id": "PCSK4_HUMAN", "id": "Q6UW60-1", "name": "Proprotein convertase subtilisin/kexin type 4", "aln": "----------------------------------------------------------------------------------------------------------------MRPAPIALWLRLVLALALVRP---------------RAVGWAPVRAP----------------------------------------------------------------------IYVSSWAVQVSQG-NREVERLARKFGFVNLG-PIFPDGQYFHLRHRGVVQQSLTPHWGHRLHLKKN-PKVQWFQQQTLQRRVKRSVVVP------------------TDPWFSKQWYMNSE--AQPDLSILQAWSQGLSGQGIVVSVLDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPSKENRHGTRCAGEVAAMANNGFCGVGVAFNARIGGVRMLDGTITDVIEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGILTREAFRRGVTKGRGGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTQQGRVPWYSEACASTLTTTYSSGVATDPQIVTTDLHHGCTDQHTGTSASAPLAAGMIALALEANPFLTWRDMQHLVVRASKPAHLQAE-DWRTNGVGRQVSHHYGYGLLDAGLLVDTARTWLPTQPQRKCAVRVQSR-PTPILPLIYIRENVSACAG--LHNSIRSLEHVQAQLTLSYSRRGDLEISLTSPMGTRSTLVAIRPLDVSTEGYNNWVFMSTHFWDENPQGVWTLGLENKGYYFNTGTLYRYTLLLYGTAEDMT-------ARPTGPQVTSS--ACVQR----------------------------------------------------DTEGLCQACDGPAYILGQLCLAY--------------------------------------------CPPRFFNHTRLVTAGPG-------HTAAPALRVCSSCHASCYTCRGGSPRDCTSCPPSSTLDQQQGSCMGPTTP-------------------DSRPRLRAAACPHHRCPASAMVLSLLAVTLGGPVLCGMSMDLPLYAWLSRARATPTKPQVWLPAGT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26016-1", "uniprot_id": "FUR11_DROME", "id": "P26016-1", "name": "Furin-like protease 1, isoforms 1/1-X/2", "aln": "MKNDVVRWSRQPTSNTTNSSSSSRSDSNSTHKHRSKSNKLNARQLGSNAARSCQQRSSVATTLEDEQQTIIECDIGNFNFDCNLFKTSFLTQHKQKRSGKSSSKSKSNRSRPLAKTKAVFLLALQFSAVVFLCNINVGFVAGSVATAASSAGGSSPAAPSSAPSSPPTVAVPPPPPPSSALKVDPNGQSPVLPPYVLDYETGGKAKLTPNNGKFGQSGSSGSNNNHIVGHYTHTWAVHIPNGDNGMADAVAKDHGFVNLG-KIFDD--HYHFAHHKVSKRSLSPATHHQTRLDDD-DRVHWAKQQRAKSRSKRDFIRMRPSRTSSRAMSMVDAMSFNDSKWPQMWYLNRG--GGLDMNVIPAWKMGITGKGVVVTILDDGLESDHPDIQDNYDPKASYDVNSHDDDPMPHYDMTDSNRHGTRCAGEVAATANNSFCAVGIAYGASVGGVRMLDGDVTDAVEARSLSLNPQHIDIYSASWGPDDDGKTVDGPGELASRAFIEGTTKGRGGKGSIFIWASGNGGREQDNCNCDGYTNSIWTLSISSATEEGHVPWYSEKCSSTLATTYSSGGQGEKQVVTTDLHHSCTVSHTGTSASAPLAAGIAALVLQSNQNLTWRDLQHIVVRTAKPANLKDP-SWSRNGVGRRVSHSFGYGLMDAAEMVRVARNWKAVPEQQRCEINAPHV-DKVIPPRTHITLQLTVNHC----RSVNYLEHVQAKITLTSQRRGDIQLFLRSPANTSVTLLTPRIHDNSRSGFNQWPFMSVHTWGESPQGNWQLEIHNEGRYMGHALLREWSLIFYGTTQSIGPNDPISVPKPSGSEATTPNSSSTTSNLHQAYSPQYPRIPPNNFGSSPSGGSKLPLGKVPPPNKSSYVTNNPLLNSAPPKQGYQQISATYGVILGKANGKSNNNSKEKTNNKGNKSNNGNKGKSGGSSGNRKEQTTQSTIIQTSTSKNKYYRISQQQQQKNNKQDRNGVQTQRPKANSGEKSYDEKSRKVVGEITTNSGNGSIKAAKQVKESTTTSSNSRIPKLFERYEKIQAIFPELEPYENSSPKGKPKQAKQGKQFEVDLFKPTNGGNSRQGNTKKSPSVPPPSQTMATLSILPILPAGGSSFLPDQKILKKQQLLMAAAGVMAPAQVEVEMEEVHATPDYEARKDQRKEVNGPNAQITQWDMIFYGTETPAQPDDVANPSQSNQFNLYGNDMAHNDVEYDSTGQWRNMQQVGEVGMTRDHSNTAACLKWSDRKCLGLSLLFFMIMQVFFLNFKHANDNNNKNKNNIIKCIR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13134-1", "uniprot_id": "KEX2_YEAST", "id": "P13134-1", "name": "Kexin", "aln": "-------------------------------------------------------------------------------------------------------------MKVRKYITLCFWWAFSTSALVSSQ----------------QIPLKDHTSR----------------------------------------------------------------------QYFAVESNETLSRLEEMHPNWKYEHDVRGLPNHYVFSKELLKLGKRSSLEELQGDNNDHILSVHDLFPRNDLFKRLPVPAPPMDSSLLP--------VKEAEDKLSINDPLFERQWHLVNPSFPGSDINVLDLWYNNITGAGVVAAIVDDGLDYENEDLKDNFCAEGSWDFNDNTNLPKPRLS---DDYHGTRCAGEIAAKKGNNFCGVGVGYNAKISGIRILSGDITTEDEAASLIYGLDVNDIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYVFASGNGGTRGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTYSSG--SGEYIHSSDINGRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVGLEKNADGDWRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLPTLYVSQSTNSTEETLESVITISEKSLQDANFKRIEHVTVTVDIDTEIRGTTTVDLISPAGIISNLGVVRPRDVSSEGFKDWTFMSVAHWGENGVGDWKIKVKTTENGH-RIDFHSWRLKLFGESIDSSKTETFVFGNDKEEVEPAATESTVSQYS-----------------------------------------------ASSTSISISATSTSSISIGVETSAIPQTTTASTDPDS--------------------DPNTPKKLSSPRQAMHYFLTIFLIGATFLVLYFMFFMKSRRRIRRSRAETYEFDIIDTDSEYDSTLDNGTSGITEPEEVEDFDFDLS---------------------DEDHLASLSSSENGDAEHTIDSVLTNENPFSDPIKQKFPNDANAESASNKLQELQPDVPPSSGRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . * : . . .... .* . . :: :: :. * :.. : :: . : .*. : : *:: *:.:: * .::* *:* :::***:: :: *: *: . .*:*.*. * *: .: ********::* .*.**..*:.:.* :.*:*:*.* :* ** ** : .***.**** ***: ::**. *. .*: .*.*:** . *:::::****** . **** ******* ::::.: .:. * *** *::.::.*:*** : ::*:: *: .* ****:******: :* *::* *****:*:: : :: . : .* ..:*:: ** :*:* :** :: :: * . * : . . . : :: .. :*** . : : . ** : * ** . .* . * * * .*:::* ***. *.*. * * : :.. : * ::* : . . . * . : :. . . : . ", "identical_positions": 144, "similar_positions": 190, "identity": "11.24%" }, { "cls_id": "homologset.agr.RGD:620326", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04592-1", "uniprot_id": "PCSK5_MOUSE", "id": "Q04592-1", "name": "Proprotein convertase subtilisin/kexin type 5", "aln": "--------------------------------------------------------------------------------MDWDWGNRCSRPGRRDLLCVLALLAGCLLPVCRTR--------------------------------------------------------------------------------------------------------------------------VYTNHWAVKIAGGFAEADRIASKYGFINVGQIGALKDYYHFYHSRTIK--RSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRD-----------YDLSHAQSTYFNDPK----------------------------------WPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDGDVTDMVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGES-YDKKIITTDLR------QRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN-ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIR--PNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERFRYSRVEDPTDDYGAEDYAGPCDPECSEVGCDGPGPDHCSDCLHYYYKLKNNTRICVSSCPPGHYHADKKRCRKCAPNCESCFGSHGNQCLSCKYGYFLNEETSSCVTQCPDGSYEDIKKNVCGKC-SENCKACIGFHNCTECKGGLSLQGSRCSVTCEDGQFFNGHD--CQPCHRFCATCSGAGADGCINCTEGYVMEEGRCVQSCSVSYYLDHSSEGGYKSCKRCDNSCLTCNGPGFKNCSSCPSGYLLDLGTCQMGAICKDGEYIDDQGHCQTCEASCAKCWGPTQEDCISCPVTRVLDDGRCVMNCPSWKFEFKKQCHPCHYTCQGCQGSGPSNCTSCRADKHGQERFLYHGECLENCPVGHYPAKGHACLPCPDNCELCYNPHVCSRCMSGYVIIPPNHTCQKLECRQGEFQDSEYEECMPCEEGCLGCTEDDPGACTSCATGYYMFERHCYKACPEKTF--GVKWECRACGTNCGSCD---QHECYWCEEGFFLSGGSCVQDCGPGFHGDQELGECKPCHRACENCTGSGYNQCSSCQEGLQLWHGTCLWSTWPQVEGKDWNEAVPTEKPSLVRSLLQDRRKWKVQIKRDATSQNQPCHSSCKTCNG---SLCASCPTGMYLWLQACVPSCPQGTWPSVTSGSCEKCSEDCVSCSGADLCQQCLSQPDNTLLLHEGRCYHSCPEGFYAKDGVCEHCSSPCKTCEGNATSCNSCEGDFVLDHGVCWKTCPEKHVAVEGVCKHCPERCQDCIHEKTCKECMPDFFLYNDMCHRSCPKSFYPDMRQ--CVPCHKNCLECNGPKEDDCKVCADTSKALHNGLCLDECPEGTYKEEENDECRDCPESCLICS--SAWTCLACREGFTV-VHDVCTAPKECAAVEYWDEGSHRCQPCHKKCSRCSGPSEDQCYTCPRETFLLNTTCVKECPEGYHTDKDSQQCVLCHSSCRTCEGPHSMQCLSCRPGWFQLGKECLLQCRDGYYGESTSGRCEKCDKSCKSCRGPRPTDCQSCDTFFFLLRSKGQCHRACPEHYYADQHAQTCERCHPTCDKCSGKEAWSCLSCVWSYHLLKGICIPECIVGEYREGKGENFNCKKCHESCMECKGPGSKNCTGCSAGLLLDMDDNRCLHCCN----ASHSRRSQDCCDCQSSTDECILPAR-EAEFYEHT----KTALLVTSGAMLLLLLGAAAVVWRKSRS------RPVAKGRYEKLAE-------------PTVSYSSYRSSY-----LDEDQVIEYRDR-----DYDEDDED-DIVYMGQDGTVYRKFKYGLLDETEDDELEYDDESYSYQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41413-1", "uniprot_id": "PCSK5_RAT", "id": "P41413-1", "name": "Proprotein convertase subtilisin/kexin type 5", "aln": "--------------------------------------------------------------------------------MDWGWGSRCCRPGRRDLLCVLALLAGCLLPVCRTR--------------------------------------------------------------------------------------------------------------------------VYTNHWAVKIAGGFAEADRIASKYGFINVGQIGALKDYYHFYHSRTIK--RSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRD-----------YDLSRAQSTYFNDPK----------------------------------WPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDGDVTDMVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGES-YDKKIITTDLR------QRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN-ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIR--PNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERFRYSRVEDPTDDYGAEDYAGPCDPECSEVGCDGPGPDHCTDCLHYHYKLKNNTRICVSSCPPGHFHADKKRCRKCAPNCESCFGSHADQCLSCKYGYFLNEETSSCVAQCPEGSYQDIKKNICGKC-SENCKTCTGFHNCTECKGGLSLQGSRCSVTCEDGQFFSGHD--CQPCHRFCATCAGAGADGCINCTEGYVMEEGRCVQSCSVSYYLDHSLEGGYKSCKRCDNSCLTCNGPGFKNCSSCPSGYLLDLGMCQMGAICKDGEYIDEQGHCQICDASCAKCWGPTQDDCISCPITRVFDDGRCVMNCPSWKFELKKQCHPCHHTCQGCQGSGPSNCTSCKA---------------------------------------------------------------------GEFQDSEYGECMPCEEGCVGCTVDDPGACTSCATGYYMFERHCYKACPEKTF--GEKWECKACGTNCGSCD---QHECYWCEEGFFLSSGSCVQDCDPGFYGDQELGECKPCHRACETCTGLGYNQCSSCPEGLQLWHGTCIWPTWPHVEGKVWNEAVPTEKPSLVRSLPQDRRKWKVQIKRDATRQYQPCHSSCKTCNG---SLCTSCPAGTYLWLQACVPSCPQGTWLSVRSSSCEKCAEGCASCSGDDLCQRCLSQPSNTLLLHEGRCYHSCPEGFYAKDGVCEHCSSPCKTCKGNATSCHSCEGDFVLDHGVCWETCPEKHVAVEGVCKHCPERCQDCIHEKTCKECMPDFFLYNDMCHHSCPKNFYPDMRQ--CVPCHKNCLGCNGPKEDDCKACADTSKVLHNGLCLDECPKGTYKDEVNDECRDCPESCLICS--SAWTCLTCREGFTV-VQDVCTAPKECAAIEYWDVGSHRCQPCHRKCSRCSGPSENQCYTCPRETFLLNTTCVKECPEGYHTDKDSHQCVPCHSSCRTCEGPHSMQCLSCRPGWFQLGKECLLQCRDGYYGESTSGRCEKCDKSCKTCRGPQPTDCQSCDTFFFLLRSKGQCHLACPEHYYADQHAQTCERCHPTCDKCSGKEAWNCLSCVWSYHLLKGICTPECIVGEYRDGKGENFNCKKCHESCMECKGPGSKNCTGCSAGLLLQMDDSRCLRCCN----ASHPHRSQDCCDCQSSTDECILPASDDTVFHEHT----KTALLVTSGAMLLLLLGAAVVVWRKSRS------QPVAKGRYEKLAE-------------PTVSYSSYRSSY-----LDEDQVIEYRDR-----DYDEDDED-DIVYMGQDGTVYRKFKYGLLDEAEDDELEYDDESYSYQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92824-1", "uniprot_id": "PCSK5_HUMAN", "id": "Q92824-1", "name": "Proprotein convertase subtilisin/kexin type 5", "aln": "----------------------------------------------------------------------------------MGWGSRCCCPGRLDLLCVLALLGGCLLPVCRTR--------------------------------------------------------------------------------------------------------------------------VYTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIK--RSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRD-----------YDFSRAQSTYFNDPK----------------------------------WPSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLDGDVTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGES-YDKKIITTDLR------QRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLN-ANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIR--PNSAVRSIYKASGCSDNPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERFRYSRVEDPTDDYGTEDYAGPCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHYHADKKRCRKCAPNCESCFGSHGDQCMSCKYGYFLNEETNSCVTHCPDGSYQDTKKNLCRKC-SENCKTCTEFHNCTECRDGLSLQGSRCSVSCEDGRYFNGQD--CQPCHRFCATCAGAGADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLLDLGMCQMGAICKDGEYVDEHGHCQTCEASCAKCQGPTQEDCTTCPMTRIFDDGRCVSNCPSWKFEFENQCHPCHHTCQRCQGSGPTHCTSCGADNYGREHFLYQGECGDSCPEGHYATEGNTCLPCPDNCELCHSVHVCTRCMKGYFIAPTNHTCQKLECGQGEVQDPDYEECVPCEEGCLGCSLDDPGTCTSCAMGYYRFDHHCYKTCPEKTY--SEEVECKACDSNCGSCD---QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWN---------------------------DILRKLQPCHSSCKTCNGSA-TLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH--CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLTCS--SSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCN----TSDPPSAQECCDCQDTTDECILRTSKVRPATEHF----KTALFITSSMMLVLLLGAAVVVWKKSRGR----VQPAAKAGYEKLAD-------------PNKSYSSYKSSYRESTSFEEDQVIEYRDR-----DYDEDDDD-DIVYMGQDGTVYRKFKYGLLDDDDIDELEYDDESYSYYQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q4U3-1", "uniprot_id": "A0A8M9Q4U3_DANRE", "id": "A0A8M9Q4U3-1", "name": "", "aln": "--------------------------------------------------------------------------------------------MTSTIFFPYALFFGIGLQCVQMR--------------------------------------------------------------------------------------------------------------------------LYTNRWAVKITGGPEAADLIAEKYGFVNMGQIGGLVDHYQFQHSGIIK--RSTIKSKGNHSLITMETKVEWIQQQMVQKRVKRT-----------ETMDQTHDGSFNDPK----------------------------------WDSMWYIHCDHN---CLTDMNIQAAWRRGYTGKGVVVSILDDGIERQHPDLKQNYDARASYDVNGNDPDPTPRYDVTNENKHGTRCAGVVAASANNSLCIVGIAYNAKIGGVRMLDGDMTDMVEAQSLNLRQQYIDIYSSSWGPDDDGRTVDGPGPLARLALENGIRKGRKGRGSIFVWASGNGGQSQDHCSCDGYTNSIYTISVGSTTQSGRKPWYLEECSSTLATTYSSGDS-HSPGVVTTDLR------QRCTDEHSGTSASAPMAAGIIALTLEANPALTWRDIQHIIVKTSSRGHLS-ASDWQSNGAGYDVSHLYGFGLLNAEAMVKNAETWKQVPSQHICEENIGQNARIIS--PERVLRSVLKSSGCSAQRLQRVVYLEHVIVRVTITHPHRGDLSITLTSPSGTTSQLLANRPNDHSSEGFIKWEFMTTHCWGERLAGDWILDIRDTPSPQRNNRLQGKLVEWSLVLYGTSTHPYIR-HEQPRSAQL-------PSEDEITEEYNGSCDPECSEDGCEGPGPHQCVSCLNLFLKFKNNTRTCVSECPSG-YWGDKKRCKKCYSSCKSCLGSRSDQCTACKSGYHLNEEKNNCVTSCEDGYFLYHEENLCRKCNIENCMKCTSASICTECSEGTSLVGNRCQKSCEVGSYYSEPEDSCEACHPACATCAAAGLESCNRCAEGYLMENWRCVSSCSQGFYAEQQNSDNQSTCKRCDASCLACVGPTKTNCSECVDGHSLQDGVCVLSHNCGDGEYQDESGECQSCHVSCQKCKGPQSEDCLSCFITHLLDYGQCVVSCSNGKYPSGGQCHLCDHTCAQCVDAGPSNCTSCDTDKFGVDRYLYHGECVDACPKAHFHTVLKACEPCPSYCKLCSSATHCIKCEDSFYVN--NGVCNKLECGEGEVEDPEYDDCMPCEEGCHKCVLYNPKHCLSCINGYYRFEESCYKNCPSKTYPVEETMSCVSCEHDCVNCD---EDECSWCEADFFISNGKCVRECPDGFYNDDESQECEECHSDCKTCSGPEDSDCESCSEGLTLDNGACVSEQDVCPAQMYLTD----------------------------DGECEACHPLCESCWGKMKNQCNTCVKGRYLNADQCVARCPVGSFGSKDSGHCETCPQGCAQCQDEQLCTRCQSTRKNPLYLQAGQCVRKCTRG-YPVGQVCKSCASACTSCEKNATHCMSCEGTLLLYKHECVSSCPSAHTVSNGECVQCQENCAICS-EDGCTGCKEDYFLHVGQCIAVCPDGFFEDMNQGICKRCHVDCSLCDGPESNNCDACSDSDSTLHYGACLTPCSSHTYRESRSGECIDCDSSCLTCSGPHDTSCTSCSEGLKMDAHGRCATPTTCPSHHYSNQDGE-CHLCHKYCHECSGPHQDQCLSCNQKHYLLNGSCVNNCPDEYFSG-ETQRCEPCHPNCLTCMGRHSHECLSCRDHLYRDVKECVDTCRSGYYASAVSSTCERCDESCGECLQAGAEGCVSCRQGMLFIRKQGRCVSSCPESYYHDTHHKTCEACHPSCRTCIGKSVEDCDTCYPGFTLTGGVCESPCITGEYAKSEEQDYNCESCDESCLECKGPGPHNCTICPAQFILASE-GRCLPCCTNTELEDAATVQQECCNCTENRGECVLSTNFAFRNHEEEDYTGNLPLFITTSILLVFVLIAVIMLIKRSLSKRALPDTPVPRG-YEKLGHDGGRDSFYRGTSSATSAYSGQASSS--SGHFRESKLVDLGDQKGSRDDDDEDDEDEDIVYMGQDGTVYRKFKYGQLGDEQEDELEYDDESYNYR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P30432-1", "uniprot_id": "FUR2_DROME", "id": "P30432-1", "name": "Furin-like protease 2", "aln": "MSNTTRSSRVTIGRIGTTPQITDPWSSGLEKQRPSRCGGPKSLAEPTYRKIGRRKMMLHMRVHDPGTTVTQRAKETATAKLNRIYLCTFNRMAQSCIYFVLFLVILSPNTSCALRSSAGETQNYVGILSNDSATTTYDVSSLHSSRRTNPPSSSSSSSSNVDVDYRNDRELHKVDLVGLGGERAGQAETISGGKYDYNYENTHTNASAKDEIVERQSNSLDFDGVDMFGAFSIPEEAIYTNEFAVNIPAGKQMADVIATKHGFINRGQIGSLDNYYLFQHHHVSK--RSLRSSRKHQGALKSENEVKWMQQQHEKVRRKRDGPYQDLPTYSPYNLLRQHGGYVVDPNPHLSFSPESISLASHSQRMEYRDVSSHFIFPDPLFKEQWYLNGGAKDG---LDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGNDSDPTPQDNG--DNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLDGKVNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDHICTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSRPAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGCAG-TINEVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVKSNFDDWPFLSVHFWGEKAEGRWTLQVING--GRRRVNQPGILSKWQLIFYGTSTQPMRLKSELLN------------------------------------SSPQLRSPSSSNPFLFPSASNIGQPANEGGNFNTDSFASYLNYQNIFSSAGSDPEPATATLDGQNVTAAIAGGSSAESLG----------------FTASAAQLVAAPETRDGDKKILHSCDAECD------------------SSGCYGRGPTQCVACSHYRLDN--TCVSRCPPRSFPNQVG-----ICWPCHDTCETCAGAGPDSCLTCAPAHLHVIDLAVCLQFCPDG-----------------------------------------------------------------------------------------------------------------------------------------------------YFENSRNRTCVPCEPNCASCQ-DHPEYCTSCDHHLVMHEHKCYSACPLDTY-ETEDNKCAFCHSTCATCNGPTDQDCITCRSSRYAWQNKCLISCPDGFYADKKRLECMPCQEGCKTCTSNGVCSECLQNWTLNKRDKCIVSGSEGCSESEFYSQ---------------------------VEGQCRPCHASCGSCNGPADTSCTSCPPNRLLEQSRCVSGCREGFFVEAGS-LCSPCLHTCSQCVSRTNCSNCSKG----LELQNGECRTTCADGYYSDRGICAKCYLSCHTCSG--------------------------------------------PRRNQCVQCPAGWQLAAGECHPECPEGFYKSDFG--CQKCHHYCKTCNDAGPLACTSCPPHS--MLDGGLCMECLSSQYYDTTSATCKTCHDSCRSCFGPGQFSCKGCVPPLHLDQLNSQCVSCCQNQTLAEKTSSAACCNCDGETGECKATS-----TGGKRRTVVGSGSAYKSSESKHGSFENDGNAREFVLRLDSP-LTAITAIAVAICLLIITIFSIIFAVLQRNSNHVSRNSVRYRKIANTSSG----------------RRKNLSAKPTSDARFIFNIGEDDDTDGDNSDDELDGNVGTDINNRIVYDRKGNDHGHEFYIESTNDIDAIEFHCN----------GAGAQKAETQLQRCNANGDDDDILHYDR------HTNAERKNHPSSTTSRTNIRS-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13134-1", "uniprot_id": "KEX2_YEAST", "id": "P13134-1", "name": "Kexin", "aln": "--------------------------------------------------------------------------------------MKVRKYITLCFWWAFSTSALVSSQQIPLK--------------------------------------------------------------------------------------------------------------------------DHTSRQYFAVESNETLSRLEEMHPNWKYEHDVRGLPNHYVFSKELLKLGKRSSLEELQGDNNDHILSVHDLFPRNDLFKRLPVPAPPMDS---SLLPVKEAEDKLSINDP---------------------------------LFERQWHLVNPSFPG---SDINVLDLWYNNITGAGVVAAIVDDGLDYENEDLKDNFCAEGSWDFNDNTNLPKP---RLSDDYHGTRCAGEIAAKKGNNFCGVGVGYNAKISGIRILSGDITTEDEAASLIYGLDVNDIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYVFASGNGGTRGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTYSSGSG---EYIHSSDIN------GRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVGLEKNADGDWRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLPTLYVSQSTN-STEETLESVITIS-EKSLQDANFKRIEHVTVTVDIDTEIRGTTTVDLISPAGIISNLGVVRPRDVSSEGFKDWTFMSVAHWGENGVGDWKIKVKTTENGHRID-----FHSWRLKLFGESID-----------------------------------------------------SSKTETFVFGNDKEEVEP----------------------AATESTVSQYSASSTSISISATSTSSISIG------------------------------------------------------------------------------------------------------------------------VETSAIPQTTTASTDPD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDPNTPKKLSSPRQAMHYFLTIFLIGATFLVL-----------------------------YFMFFMKSRRRIRRSRAETYEFDIIDTDSEYDSTLDNGTSGITEPEEVEDFDFDLSDEDHLAS-------------------------------------------------LSSSENGDAEHTIDSVLTNENPFSDPIKQKFPNDANAESASNKLQELQPDVPPSSGRS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*.. . : .. : : .: :: .* ::* * : ** .. .. . : :: * . . .. : : *:: *:*: * .. ** .:*.:*:***:: : ** :*: . .* *.*.* * * :: ******* :** *. * **:.:**.*.*:*:*.*.:. ** :: . .***.**** *** ::**. *.: *: *: ** . *:::*:****** * *. *******:::::.: . . :* * * **:.:*.***** : : *: *: .* ****:**:***: :* ***** *****:*:: : :: . ..* .. . ** :*:* ::* :: :: * * * : .: : . .. :*** : : ** : * ** * * * * * ..* .* *:: ***. * * :.: * : .* * ::* * . . : . .. . :. * . : . :. . : :. . .. . * * . .. . : : . : . . .. :. : : . : * : . . . . * . . . ", "identical_positions": 158, "similar_positions": 201, "identity": "7.21%" }, { "cls_id": "homologset.agr.RGD:620327", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5GF25-1", "uniprot_id": "MANEA_RAT", "id": "Q5GF25-1", "name": "Glycoprotein endo-alpha-1,2-mannosidase", "aln": "-----MAKFRRRTCIILSLFIVFIFSLMMGLKMLWPNAASFGPPFGLDLLPELRPPNTHLENKADFQRSDRIDMETNTKDLKGAGVTVH----PPRASEVNLEELPPLNYFVHAFYYSWYGNPQFDGKYVHWNHPVLEHWDPRIAKNYPQGRHS---------PPDDIGSSFYPELGSYSSRDPSVIETHMKQMRSASIGVLALSWYPPDASDENGEATDYLVPTILDKAHKYNLKVTFHIEPYSNRDDQNMHQNVKYIIDKYGNHPAFYRYKTRMGHSLPMFYIYDSYITKPKTWANLLTPSGSQSVRGSP--YDGLFIALLVEEKHKYDILQSGFDGIYTYFATNGFTYGSSHQNWNKLKSFCEKNNMIFIPSVGPGYIDTSIRPWNTQNTRNRINGKYYEVGLSAALQTQPSLISITSFNEWHEGTQIEKAVPKRTANTVYLDYRPHKPSLYLEITRKWSEKYSKERMTYALDQQLPAS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NXH2-1", "uniprot_id": "MANEA_MOUSE", "id": "Q6NXH2-1", "name": "Glycoprotein endo-alpha-1,2-mannosidase", "aln": "-----MAKFRRRTCILLSLFILFIFSLMMGLKMLWPNAASFGPPFGLDLLPELHPLNAHSGNKADFQRSDRINMETNTKALKGAGMTVL----PAKASEVNLEELPPLNYFLHAFYYSWYGNPQFDGKYIHWNHPVLEHWDPRIAKNYPQGQHS---------PPDDIGSSFYPELGSYSSRDPSVIETHMKQMRSASIGVLALSWYPPDSRDDNGEATDHLVPTILDKAHKYNLKVTFHIEPYSNRDDQNMHQNIKYIIDKYGNHPAFYRYKTRTGHSLPMFYVYDSYITKPTIWANLLTPSGSQSVRSSP--YDGLFIALLVEEKHKNDILQSGFDGIYTYFATNGFTYGSSHQNWNNLKSFCEKNNLMFIPSVGPGYIDTSIRPWNTQNTRNRVNGKYYEVGLSAALQTHPSLISITSFNEWHEGTQIEKAVPKRTANTIYLDYRPHKPSLYLELTRKWSEKFSKERMTYALDQQQPAS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SRI9-1", "uniprot_id": "MANEA_HUMAN", "id": "Q5SRI9-1", "name": "Glycoprotein endo-alpha-1,2-mannosidase", "aln": "-----MAKFRRRTCIILALFILFIFSLMMGLKMLRPNTATFGAPFGLDLLPELHQRTIHLGKNFDFQKSDRINSETNTKNLKSVEITMK----PSKASELNLDELPPLNNYLHVFYYSWYGNPQFDGKYIHWNHPVLEHWDPRIAKNYPQGRHN---------PPDDIGSSFYPELGSYSSRDPSVIETHMRQMRSASIGVLALSWYPPDVNDENGEPTDNLVPTILDKAHKYNLKVTFHIEPYSNRDDQNMYKNVKYIIDKYGNHPAFYRYKTKTGNALPMFYVYDSYITKPEKWANLLTTSGSRSIRNSP--YDGLFIALLVEEKHKYDILQSGFDGIYTYFATNGFTYGSSHQNWASLKLFCDKYNLIFIPSVGPGYIDTSIRPWNTQNTRNRINGKYYEIGLSAALQTRPSLISITSFNEWHEGTQIEKAVPKRTSNTVYLDYRPHKPGLYLELTRKWSEKYSKERATYALDRQLPVS------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EYY9-1", "uniprot_id": "E7EYY9_DANRE", "id": "E7EYY9-1", "name": "Glycoprotein endo-alpha-1,2-mannosidase", "aln": "-----MARFRRKSCCAVIVLALAVFIITVILKSLSPEDNISGSHFAVKLIP--------------FPK-ENTNLILSPK--PVLMIPLE----KPEKMENELQDFPEPNYNVHAFYYVWYGSPQFDGKYVHWDHPLLPHWDPKVASSYSTGRHQ---------PPEDIGANFYPALGPYSSRDPAVLEEHMRQLRMAAVGVLAVSWYPRSMKDDNGEEIDSLLPLILDAADKNQLKVVFHIEPYKGRDDANMRENIQYIVDRYGNHPAFYKYKTSTGKLLPLYYIYDSYLQTPDVWAQLLKPNGISTVRNTP--YDGIFIALLVEERHKKDILTAGFDGLYTYFATNGFTYGSSHHNWRTIKTFCDYNDLVFIPSVGPGYIDTSIRPWNAQNTRNRINGKYYETAFNAAVDARPQIISITSFNEWHEGTQIEKAIPKTWGKTVYLDYLPHKPTVYLEITQRWARKFSDEQKKWLE-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMQ2-1", "uniprot_id": "Q9VMQ2_DROME", "id": "Q9VMQ2-1", "name": "Glycoprotein endo-alpha-1,2-mannosidase", "aln": "MLLKKYVKTRRKLKILLLLAIVALLVITIIVLGSSGRNAAIELLLDERFIARAYRPGDQPQVAEKPPPVAVALLQPQRENGVIVPEKYDEQKIKERIIQSKIDLMKQQQQRDHEAEQSSRTTLDVVISAVHIFYTAPVPWYKSKKPPPPPAEHPNDVPLTTPRPVRILNTAFYPALGLYKPSG-SLLAQHFENIRSCGIGVLILSFS------GGKPAEAALLHQILELAPQHNLSVTFELSVAGNQSVEFVRQQLQEIATYTSLAGFYKVWSQSRGVSLPVLYVSNAYKLSDSLGRLLCRSPSLVEPDGLRRILDALFIGHIRLKSHADVLRRLCFDGFYSKLPSNGAVFASTWKNWSYLKSFALSYKMLFVPTVGPGFAERNKFPRHGDIQRHRSNGRYYGVAWRTAILNHVGFINIASYNNWPDGSQIEEVMPRAG----FLDYNPGSRTKYLDLTAHWVGNFLKTRQEAAAAASPASPPNCYELLNGTIC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: **: : : : :: : : : . : ::. . : . : ::: : : * . :. . :* :. * . ..* * :.: *** ** *.. . ::: *:.::* ..:*** :*: . *: **: * : :*.*.*.:. .:. : :::: * . : :. * **: *: ::* . * . . . *.:**. : : * : ***:*: :.:** .:.*: :** :* *. .::*:*:****: : . * : : *:* **:** . :*: : :*.*:*:*:* :*:***:.:*: :*** * . **::* :* :: . : ", "identical_positions": 80, "similar_positions": 137, "identity": "16.19%" }, { "cls_id": "homologset.agr.RGD:620328", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88178-1", "uniprot_id": "B3GT4_RAT", "id": "O88178-1", "name": "Beta-1,3-galactosyltransferase 4", "aln": "------MPLSLFRRLLLAVLLLVIIWTLFGPSGLGEELLSLSLASLLPAP-----ASPG--PPLALPRLLIPNPQACGGSGP----------------PPFLLILVCTAPEH----LNQRNAIRGSWGAIREARGFRVQTLFLLGEPMGQ------QFADLASES-------------AAQGDVLQASFQDSYRNLTLKTLTGLNWVNKYCPMA----------RYILKTDDDVYVNVPELVSELIQRGGPSEQ---WQKGKEPQ-EETTAVHKEHKGQAVPLLYLGR--------VHWRVRPTRTPESRHHVSEELWP-----------------------------------------ENWGPFPP-YASGTGYVLSISAVQLILKVASRAPYLP-------LEDVFVGVSARRV---GLAPTHCVKLAGATHYPLDRCCYGKFLLTSHKVDP------WKMQEAWKLVRGLNGRRTEPFCSWLQGFLGTLRCRFIAWLNS----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0F0-1", "uniprot_id": "B3GT4_MOUSE", "id": "Q9Z0F0-1", "name": "Beta-1,3-galactosyltransferase 4", "aln": "------MPLSLFRRVLLAVLLLVIIWTLFGPSGLGEELLSLSLASLLPAP-----ASPG--PPLALPRLLISNSHACGGSGP----------------PPFLLILVCTAPEH----LNQRNAIRASWGAIREARGFRVQTLFLLGKPRRQ------QLADLSSES-------------AAHRDILQASFQDSYRNLTLKTLSGLNWVNKYCPMA----------RYILKTDDDVYVNVPELVSELIQRGGPSEQ---WQKGKEAQ-EETTAIHEEHRGQAVPLLYLGR--------VHWRVRPTRTPESRHHVSEELWP-----------------------------------------ENWGPFPP-YASGTGYVLSISAVQLILKVASRAPPLP-------LEDVFVGVSARRG---GLAPTHCVKLAGATHYPLDRCCYGKFLLTSHKVDP------WQMQEAWKLVSGMNGERTAPFCSWLQGFLGTLRCRFIAWFSS----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96024-1", "uniprot_id": "B3GT4_HUMAN", "id": "O96024-1", "name": "Beta-1,3-galactosyltransferase 4", "aln": "------MQLRLFRRLLLAALLLVIVWTLFGPSGLGEELLSLSLASLLPAP-----ASPG--PPLALPRLLIPNQEACSGPGA----------------PPFLLILVCTAPEN----LNQRNAIRASWGGLREARGLRVQTLFLLGEPNAQHPVWGSQGSDLASES-------------AAQGDILQAAFQDSYRNLTLKTLSGLNWAEKHCPMA----------RYVLKTDDDVYVNVPELVSELVLRGGRWGQ---WERSTEPQREAEQEGGQVLHSEEVPLLYLGR--------VHWRVNPSRTPGGRHRVSEEQWP-----------------------------------------HTWGPFPP-YASGTGYVLSASAVQLILKVASRAPLLP-------LEDVFVGVSARRG---GLAPTQCVKLAGATHYPLDRCCYGKFLLTSHRLDP------WKMQEAWKLVGGSDGERTAPFCSWFQGVLGILRCRAIAWLQS----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLS8-1", "uniprot_id": "Q9VLS8_DROME", "id": "Q9VLS8-1", "name": "", "aln": "MAAMANLHNTRMLRFFLVLIVVILTIFIYASYSTTSTLTANHVHPAASPPQQLIGSHPGRQPMDQVPPVNSTDKEYNSPPGESSSKQQSVSSRHSQQLPPQQAEIHKRHPQHRLPTIDEDALLDGGSAGASPQVGGPDQTPNVMADELLEEQQYGQSVDGITGNINSSTNNNSSADTLAVKQSIPAQSPQQQLPQSQSQVQPGLSDADLLIPTSNLQKFIENADRILKNITSNSSTGNPSDMAQLNAVDGKLEVSGVESEKQEPESKVIQEIKEAKKEAAVPLPKSAKPPVPPVKTTKSKVPSAPVDPSKGVATETLYEPGHVDEEIDAERICPKGGEFIKLLVLISSAMSHDAARMSIRQTWMHYGTRRDVGMAFVLGRGTNETINKALTQENFIYGDLIRGNFIDSYNNLTLKTISTLEWADVHCPKAKYILKTDDDMFINVPKLLTFLDKHKDKRTIYGRLAKKWKPIRNKKSKYYVSVDQFAAGVFPSFTTGPAYVLTGDIVHELYVRSLKTVYLKLEDVFTTGIVAKSLNVKRVQANEFVNRRISFNPCNIRNAISVHMIKSNEQFDLWKKLLDQTTKCK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *.:*. ::::: ::.. . . * : : . ..* : ** * :* : .: . . .* ** : *:: ::: : .. .. * ** ::.. : . .::.: *.: .: : *:. : :. .**. .: * : * : : .: .. *. :::* .* .. *.: : : : *** .: .: :* .: . .: .:* : ..* : . * .:**. .: : * *. :: : : * : .:: : * .:* * : * *** . :: : ** : . ... .. .: *.: : : . ", "identical_positions": 47, "similar_positions": 138, "identity": "8.03%" }, { "cls_id": "homologset.agr.RGD:620329", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCV3-1", "uniprot_id": "DGAT2_MOUSE", "id": "Q9DCV3-1", "name": "Diacylglycerol O-acyltransferase 2", "aln": "MKTLIAAYSGVLRGERRAEAARSENKNKGSALSREGSGRWGTGSSILSALQDIFSVTWLN-RSKVEKQLQVISVLQWVLSFLVLGVA-CSVILMYTFCTDCWLIAVLYFTWLAFDWNTPKKGGRR--SQWVRNWAVWRYFRDYFPIQLVKTHNLLTTR------------------------------------------NYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVNRDTIDYLLSKNG-----------SGNAIIIVVGGAAESLSSMPGKNAVTLKNRKGFVKLALRHG-ADLVPTYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITVP-KLEHPTQKDIDLYHAMYMEALVKLFDNHKTKFGLPETEVLEVN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FVP8-1", "uniprot_id": "DGAT2_RAT", "id": "Q5FVP8-1", "name": "Diacylglycerol O-acyltransferase 2", "aln": "MKTLIAAYSGVLRGERRAEAARSENKNKGSALSREGSGRWGTGSSILSALQDIFSVTWLN-RSKVEKHLQVISVLQWVLSFLVLGVA-CSVILMYTFCTDCWLIAALYFTWLAFDWNTPKKGGRR--SQWVRNWAVWRYFRDYFPIQLVKTHNLLTTR------------------------------------------NYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVNRDTIDYLLSKNG-----------SGNAIVIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHG-ADLVPTYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITVP-KLEHPTQKDIDLYHTMYMEALVKLFDNHKTKFGLPETEVLEVN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96PD7-1", "uniprot_id": "DGAT2_HUMAN", "id": "Q96PD7-1", "name": "Diacylglycerol O-acyltransferase 2", "aln": "MKTLIAAYSGVLRGERQAEADRSQRSHGGPALSREGSGRWGTGSSILSALQDLFSVTWLN-RSKVEKQLQVISVLQWVLSFLVLGVA-CSAILMYIFCTDCWLIAVLYFTWLVFDWNTPKKGGRR--SQWVRNWAVWRYFRDYFPIQLVKTHNLLTTR------------------------------------------NYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVSRDTIDYLLSKNG-----------SGNAIIIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHG-ADLVPIYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITIP-KLEHPTQQDIDLYHTMYMEALVKLFDKHKTKFGLPETEVLEVN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V9F0-1", "uniprot_id": "DGAT2_DANRE", "id": "Q4V9F0-1", "name": "Diacylglycerol O-acyltransferase 2", "aln": "MKTILAAYSGVKKG---------------------------SGSSILSALHDLPTVPWLT-RSKMVKHLQVISVLQFIMTFLTMGIA-CSLLLMYMFCTDFWVISVLYVAWLIYDWNTPGQGGRR--STWVRDWTVWKYMRDYFPIRLIKTHNLLPSR------------------------------------------NYIFGYHPHGILCFGAFCNFGTEATGFTKVFPGIKPSLATLAGNFRLPMFREYLMCGGICPVNRNSIDYLLSSNG-----------TGNAVVIVIGGAAESLDCAPGRNSVMLKKRKGFVKLALKQG-ADLVPVYSFGENEVYKQLIFEEGSWWRTIQRKLQKFLGFAPCLFHGCGLFFPESWGLVPYCKPITTVVGEPITVP-KIEEPTQDVIDMYHAMYIRSLKSLFDNYKTRFGLNESDTLIIH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z739-1", "uniprot_id": "A1Z739_DROME", "id": "A1Z739-1", "name": "Acyltransferase", "aln": "-----------------------------------------------------MTIEWAPLRVPLERRLQTLVTSFFTYTFFTLPISSCLAVAILLYYGEMFVRSLLLIYFVKIYLDYKRNYGIMEGNGWLFYRSNWRYR-NYFPVELVKTAELPPNR------------------------------------------NYIVASFPHGILGTGTCINMSLDIDNWLSLYPHVRPKIATLDHHFKTPFLRDILRWWGMVSVSKESLSYLLSKSNDPMHKDNRDGFTSNAVAVLVGGAKEAMDSHPGQYILTLKDRKGFVKMAVRTG-SSIVPSLSFGEVDIFDQVANPPDSSLRRFQNVVKKFTGISPLLPKGRGIFN-YNYGILPHRRRIVQVVGSPIDVE-RCETPDPEYVDKIHGQVIDALARMFDEYKEKYTPNSKHIKLIIQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08650-1", "uniprot_id": "DGAT2_YEAST", "id": "Q08650-1", "name": "Diacylglycerol O-acyltransferase 1", "aln": "---MSGTFNDIRRRKKEEGSPTAG-------ITERHENKSLSSIDKREQTLKPQLESCCPLATPFERRLQTLAVAWHTSSFVLFSIF----TLFAISTPALWVLAIPYMIYFFFDRSPATGEVVNRYSLRFRSLPIWKWYCDYFPISLIKTVNLKPTFTLSKNKRVNEKNYKIRLWPTKYSINLKSNSTIDYRNQECTGPTYLFGYHPHGIGALGAFGAFATEGCNYSKIFPGIPISLMTLVTQFHIPLYRDYLLALGISSVSRKNALRTLSKNQ--------------SICIVVGGARESLLSSTNGTQLILNKRKGFIKLAIQTGNINLVPVFAFGEVDCYNVLSTKKDSVLGKMQLWFKENFGFTIPIFYARGLFN-YDFGLLPFRAPINVVVGRPIYVEKKITNPPDDVVNHFHDLYIAELKRLYYENREKYGVPDAELKIVG-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::**.: . :*. : : : :: : . :. . . . . *:: :***: *:** :* .. .*:.. .**** *: :. : . :* : : ** :*: *. *: * *: .*.:.. **.. :: :::*** *:: . .. : *..****:*:*:: * .:** :*** : :. : .* .* .:: *:: : . *:* :*::*. * *** ** : : * . :: * : * :: : : :: . . : ", "identical_positions": 61, "similar_positions": 107, "identity": "13.62%" }, { "cls_id": "homologset.agr.RGD:62033", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVA9-1", "uniprot_id": "NPFF_RAT", "id": "Q9WVA9-1", "name": "Pro-FMRFamide-related neuropeptide FF", "aln": "MDS-KWAAVLLLLLLLRNWG--HAEEAGSWGEDQVFAEEDKGPHPSQYAHTPDRI-----QTPGSLMRVLLQAMERPRRNPAFLFQPQRFGRNAWGPWS-KEQLSPQA-----REFWSLAAPQRFGKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVA8-1", "uniprot_id": "NPFF_MOUSE", "id": "Q9WVA8-1", "name": "Pro-FMRFamide-related neuropeptide FF", "aln": "MDS-KWAALLLLLLLLLNWG--HTEEAGSWGEDQVFAGEDKGPHPPQYAHIPDRI-----QTPGSLFRVLLQAMDTPRRSPAFLFQPQRFGRSAWGSWS-KEQLNPQA-----RQFWSLAAPQRFGKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15130-1", "uniprot_id": "NPFF_HUMAN", "id": "O15130-1", "name": "Pro-FMRFamide-related neuropeptide FF", "aln": "MDS-RQAAALLVLLLLIDGG--CAEGPGGQQEDQLSAEEDSEPLPPQDA-----------QTSGSLLHYLLQAMERPGRSQAFLFQPQRFGRNTQGSWR-NEWLSPRAGEGLNSQFWSLAAPQRFGKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U370-1", "uniprot_id": "A0AB32U370_DANRE", "id": "A0AB32U370-1", "name": "", "aln": "MDAGVWFMLVGVLLVMADQSRSITQDEALEQNKRLLEEDEEQDHMLERPGAAQMNGLLEDRLLVEMLRSLLHGSQRYERNPSVLHQPQRFGRGARSGLSTEERIQSRDWETVPGQIWSMAVPQRFGKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: : :**:: : . :: . :.:: ::. : . : .::: **:. : *. :.*.*******.: . :* :..: ::**:*.*******", "identical_positions": 26, "similar_positions": 43, "identity": "20.31%" }, { "cls_id": "homologset.agr.RGD:620330", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08679-1", "uniprot_id": "CISY2_YEAST", "id": "P08679-1", "name": "Citrate synthase, peroxisomal", "aln": "----------------MTVPYLNSNRNVASYLQS---NSSQEKTLKERFSEIYPIHAQDVRQFVKEHGKTKISDVLLEQVYGGMRGIPGSVWEGSVLDPEDGIRFRGRTIADIQKDLP-KAKGSSQPLPEALFWLLLTGEVPTQAQVENLSADLMSRS-ELPSHVVQLLDNLPKDLHPMAQFSIAVTALESESKFAKAYAQGIS-KQDYWSYTFEDSLDLLGKLPVIAAKIYRNVFKDGK-MGEVDPNADYAKNLVNLIGSKD---------------EDFVDLMRLYLTIHSDHEGGNVSAHTSHLVGSALSSPYLSLASGLNGLAGPLHGRANQEVLEWLFALKEEVNDDYSKDTIEKYLWDTLNSGRVIPGYGHAVLRKTDPRYMAQRKFAMDH---FPDYELFKLVSSIYEVAPGVLTEHGKTKNPWPNVDAHSGVLLQYYGLKESSFYTVLFGVSRAFGILAQLITDRAIGASIERPKSYSTEKYKELVKNIESKL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00890-1", "uniprot_id": "CISY1_YEAST", "id": "P00890-1", "name": "Citrate synthase, mitochondrial", "aln": "MSAILSTTSKSFLSRGSTRQCQNMQKALFALLNARHYSSASEQTLKERFAEIIPAKAEEIKKFKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEGIRFRGRTIPEIQRELP-KAEGSTEPLPEALFWLLLTGEIPTDAQVKALSADLAARS-EIPEHVIQLLDSLPKDLHPMAQFSIAVTALESESKFAKAYAQGVS-KKEYWSYTFEDSLDLLGKLPVIASKIYRNVFKDGK-ITSTDPNADYGKNLAQLLGYEN---------------KDFIDLMRLYLTIHSDHEGGNVSAHTTHLVGSALSSPYLSLAAGLNGLAGPLHGRANQEVLEWLFKLREEVKGDYSKETIEKYLWDTLNAGRVVPGYGHAVLRKTDPRYTAQREFALKH---FPDYELFKLVSTIYEVAPGVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAIGVLPQLIIDRAVGAPIERPKSFSTEKYKELVKKIESKN-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8VHF5-1", "uniprot_id": "CISY_RAT", "id": "Q8VHF5-1", "name": "Citrate synthase, mitochondrial", "aln": "---------MALLTA---AARLLGAKNSSCLVLAARHASASSTNLKDILSNLIPKEQARVKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKLLP-KAKGGEEPLPEGLFWLLVTGQMPTEEQVSWLSQEWAKRA-ALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGIN-RTKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSKLDWSHNFTNMLCYTE---------------PQFTELMRLYLTIHSDHDGGNVSAHTSHLVGSALSDTYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKH---LPKDPMFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSKSG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CZU6-1", "uniprot_id": "CISY_MOUSE", "id": "Q9CZU6-1", "name": "Citrate synthase, mitochondrial", "aln": "---------MALLTA---ATRLLGAKNSSCLVLAARHASASSTNLKDVLSNLIPKEQARIKTFKQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKMLP-KAKGGEEPLPEGLFWLLVTGQMPTEEQVSWLSREWAKRA-ALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGMN-RAKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSRLDWSHNFTNMLGYTD---------------PQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKH---LPKDPMFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75390-1", "uniprot_id": "CISY_HUMAN", "id": "O75390-1", "name": "Citrate synthase, mitochondrial", "aln": "---------MALLTA---AARLLGTKNASCLVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLP-KAKGGEEPLPEGLFWLLVTGHIPTEEQVSWLSKEWAKRA-ALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESNFARAYAQGIS-RTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSHNFTNMLGYTD---------------HQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKH---LPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFVDSKSG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVY5-1", "uniprot_id": "CISY_DANRE", "id": "Q7ZVY5-1", "name": "Citrate synthase, mitochondrial", "aln": "---------MSFLSISRLAPRLLSSKNAACVVVAARNASAS-TNLKDVLSDLVPKEQSRIKNFKQQYGKTSIGQITVDMVYGGMRGVKGLVYETSVLDPDEGIRFRGYSIPECQQLLP-KAPGGEEPLPEGLFWLLVTGQVPTEEQVSWLSKEWAKRA-ALPSHVVTMLDNFPTNLHPMSQFSAAITALNSESSFARAYSEGVN-KAKYWEFVYEDSMDLIAKLPCVAAKIYRNLYREGSSIGAIDSNLDWSHNFTNMLGYTE---------------PQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMNGLAGPLHGLANQEVLVWLTALQKELGGEVSDEKMRDYIWNTLKSGRVVPGYGHAVLRKTDPRYTCQREFALKH---LPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLVWSRALGFPLERPKSMSTDGLMALVGAKSG---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W401-1", "uniprot_id": "CISY_DROME", "id": "Q9W401-1", "name": "Probable citrate synthase, mitochondrial", "aln": "---------MSLYRIS--ARKLSEAQKLPNVGAYVRMIAADGKSLRDVLAAKVPQEQERVKNFRKQHGATKMGETTIDMMYGGMRGIKALVTETSVLDADEGIRFRGLSIPECQKVLP-AADGGTEPLPEGLFWLLLTGEVPTKSQVQQLSREWAERA-ALPQHVVTMLNNMPTTLHPMSQFAAAVTALNHDSKFAKAYSDGVH-KSKYWEYVYEDSMDLIAKLPVVAATIYCNTYRGGKGSRSIDSSLDWSANFVKMLGYDN---------------APFTELMRLYLTIHSDHEGGNVSAHTVHLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLVWLRKLQKEAGNNPSEEQLKEYIWKTLKSGQVVPGYGHAVLRKTDPRYTCQREFALKH---LPEDETFQLVSKIYKVVPPILTETGKVKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVSRALGVLASLVWDRALGLPIERPKSFSTDLLVKMVQK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43635-1", "uniprot_id": "CISY3_YEAST", "id": "P43635-1", "name": "Citrate synthase 3, mitochondrial", "aln": "----------------MVQRLLPGAHICRRSFNSSAIIKSSALTLKEALENVIPKKRDAVKKLKACYGSTFVGPITISSVLGGMRGNQSMFWQGTSLDPEHGIKFQGLTIEECQNRLPNTGIDGDNFLPESMLWLLMTGGVPTFQQAASFRKELAIRGRKLPHYTEKVLSSLPKDMHPMTQLAIGLASMNKGSLFATNYQKGLIGKMEFWKDTLEDSLNLIASLPLLTGRIYSNITNEGHPLGQYSEEVDWCTNICSLLGMTNGTNSSNTCNLTSQQSLDFINLMRLYTGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPLHGLAAQEVVRFLIEMNSNISSIAREQEIKDYLWKILNSNRVIPGYGHAVLRKPDPRFTAMLEFAQKRPIEFENDKNVLLMQKLAEIAPKVLLEHGKSKNPFPNVDSASGILFYHYGIRELLFFTVIFGCSRAMGPLTQLVWDRILGLPIERPKSLNLEGLEALTKASNVNKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. .*:: : * . :: : :* * :. :. ***** . . : : **.:.**:*:* :* : *. ** . .. : ***.::***:** :** *. : : *. :* :. :*..:*. :***:*:: .::::: * ** * .*: : .:*. **.::*:..** ::. ** * . * . *: *: .:: : * :* *** ** **:******** ********..*** ::.: ******** * ***: :* :..: .: :..*:*. *::.:*:**********.***: . :** .: : . . *: : ::.* :* : ** ***:****: **:*: :**: * ::**:** :**:* *..*: .* :* .:***** . : :. ", "identical_positions": 149, "similar_positions": 146, "identity": "29.68%" }, { "cls_id": "homologset.agr.RGD:620331", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63005-1", "uniprot_id": "LIS1_MOUSE", "id": "P63005-1", "name": "Platelet-activating factor acetylhydrolase IB subunit beta", "aln": "-------MVLSQRQRDELNRAIADYLRS-----------NGYEEAYSVFKKEAELDMNEELDKKYAG----------------LLEKKWTSVIRLQKKVMELES----------KLNEAKEEFTSGGPLGQKRDPKE----WIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSG---------KLLASCSADMTIKLWDFQG----FECIRTMHGHDHNVSSVAIMPNGD--HIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS-YSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG-----------------MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLN-AHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63004-1", "uniprot_id": "LIS1_RAT", "id": "P63004-1", "name": "Platelet-activating factor acetylhydrolase IB subunit alpha", "aln": "-------MVLSQRQRDELNRAIADYLRS-----------NGYEEAYSVFKKEAELDMNEELDKKYAG----------------LLEKKWTSVIRLQKKVMELES----------KLNEAKEEFTSGGPLGQKRDPKE----WIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSG---------KLLASCSADMTIKLWDFQG----FECIRTMHGHDHNVSSVAIMPNGD--HIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS-YSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG-----------------MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLN-AHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43034-1", "uniprot_id": "LIS1_HUMAN", "id": "P43034-1", "name": "Platelet-activating factor acetylhydrolase IB subunit beta", "aln": "-------MVLSQRQRDELNRAIADYLRS-----------NGYEEAYSVFKKEAELDVNEELDKKYAG----------------LLEKKWTSVIRLQKKVMELES----------KLNEAKEEFTSGGPLGQKRDPKE----WIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSG---------KLLASCSADMTIKLWDFQG----FECIRTMHGHDHNVSSVAIMPNGD--HIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS-YSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTG-----------------MCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLN-AHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T394-1", "uniprot_id": "LIS1A_DANRE", "id": "Q7T394-1", "name": "Lissencephaly-1 homolog A", "aln": "-------MVLSQRQRDELNRAIADYLRS-----------NGYEEAYSVFKKEAELDMNEELDKKYAG----------------LLEKKWTSVIRLQKKVMELES----------KLNEAKEEINIGGPIGQKRDPKE----WIPRPPEKYALSGHRSPVTRVIFHPVFSVIVSASEDATIKVWDHETGDFERT-LKGHTDSVQDISFDHTG---------KLLASCSADMTIKLWDFQG----FECIRTMHGHDHNVSSVAIMPNGD--HIVSASRDKTIKMWEVATGYCVKTFTGHREWVRMVRPNQDGTLIASSSNDQTVRVWVVATKECKAELREHEHVVECISWAPESA-HPTILEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSIG-----------------MCLMTLVGHDNWVRGVLVHPGGKYIVSCADDKTLRIWDYKNKRCTKTLS-AHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q803D2-1", "uniprot_id": "LIS1B_DANRE", "id": "Q803D2-1", "name": "Lissencephaly-1 homolog B", "aln": "-------MVLSQRQRDELNRAIADYLRS-----------NGYEEAYSTFKKEAELDVNDELDKKFAG----------------LLEKKWTSVIRLQKKVMELES----------KLNEAKEEITLGGPVGQKRDPKE----WIPRPPEKYALSGHRSPVTRVIFHPVFSLMVSASEDATIKVWDYEAGDFERT-LKGHTDSVQDISFDQTG---------KLLASCSADMTIKLWDFQG----FECIRTMHGHDHNVSSVAIMPNGD--HIVSASRDKTMKMWEVATGYCVKTFTGHREWVRMVRPNQDGTLLASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESA-HPTISEATGSENKKSGKPGPFLLSGSRDKTIKMWDISTG-----------------MCLMTLVGHDNWVRGVLFHPGGRFVVSCADDKTLRIWDYKNKRCMKTLS-AHEHFVTSLDFHKASPYVVTGSVDQTVKVWECR------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KNS3-1", "uniprot_id": "LIS1_DROME", "id": "Q7KNS3-1", "name": "Lissencephaly-1 homolog", "aln": "-----MKMVLSQRQREELNQAIADYLGS-----------NGYADSLETFRKEADLST--EVEKKFGG----------------LLEKKWTSVIRLQKKVMELEA----------KLTEAEKEVIEGAPTKNKRTPGE----WIPRPPEKFSLTGHRASITRVIFHPIFALMVSASEDATIRIWDFETGEYERS-LKGHTDSVQDVAFDAQG---------KLLASCSADLSIKLWDFQQS---YECIKTMHGHDHNVSSVAFVPAGD--YVLSASRDRTIKMWEVATGYCVKTYTGHREWVRMVRVHIEGSIFATCSNDQTIRVWLTNSKDCKVELRDHEHTVECIAWAPEAA-ASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVG-----------------LCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLY-AHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39946-1", "uniprot_id": "LIS1_YEAST", "id": "P39946-1", "name": "Nuclear distribution protein PAC1", "aln": "MTNWQQQLPLTDTQKNELDKSVLRYLNWNYKQTVRHEHAQDYESVRHAIVTLSGFLLQESVDRQEFISNNDTSNESMVDIDELLLPKKWNSIVRLQKKIIELEQNTETLVSQIKDLNTQVSELAQFKPTTSNGTSAHNVLKWIPRNLPSCLIN-VESSVTSVKLHPNLPIVFVATDHGKLYAFDLFNYTIPLASLQSHTKAITSMDVLFTNYTNSSKKNYLVIVTASKDLQIHVFKWVSEECKFQQIRSLLGHEHIVSAVKIWQKNNDVHIASCSRDQTVKIWDFHNGWSLKTFQPHSQWVRSID--VLGDYIISGSHDTTLRLTHWPSGNGLSVGTGHEFPIEKVKFIHFIEDSPEIRFRTPSTDRYKNWGMQYCVSASRDRTIKIWEIPLPTLMAHRAPIPNPTDSNFRCVLTLKGHLSWVRDISIR--GQYLFSCADDKSVRCWDLNTGQCLHVWEKLHTGFVNCLDLDVDFDSNVTPRQMMVTGGLDCKSNVFMR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:: *::**:::: ** :.* . .: . : : .:::: ** ***.*::*****::*** .*. .*. * .: . . **** . :. .:.:* * :** :.::. *::...: :* : *:.**.:: .: . . ::.:.* *: *:::.: :: *::: **:* **:* : .: :: *.***:*:*:*:. .*:.:**: * :*** : * : : *:* *:*: : : **. :* : : . * : : : : *.***:**::*::. *::** ** .***.: .: *:::.*.:***::* ** .. :* :. * * ..:*:. :: .. :*: ", "identical_positions": 98, "similar_positions": 155, "identity": "19.64%" }, { "cls_id": "homologset.agr.RGD:620332", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P68402-1", "uniprot_id": "PA1B2_HUMAN", "id": "P68402-1", "name": "Platelet-activating factor acetylhydrolase IB subunit alpha2", "aln": "MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61206-1", "uniprot_id": "PA1B2_MOUSE", "id": "Q61206-1", "name": "Platelet-activating factor acetylhydrolase IB subunit alpha2", "aln": "MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDIDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35264-1", "uniprot_id": "PA1B2_RAT", "id": "O35264-1", "name": "Platelet-activating factor acetylhydrolase IB subunit alpha2", "aln": "MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDIDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VXP4-1", "uniprot_id": "PA1B2_DROME", "id": "Q9VXP4-1", "name": "Platelet-activating factor acetylhydrolase IB subunit beta homolog", "aln": "-----MNPCVLPTPLPDLDGDKRWHSIHRRFISDCREKDPDVIFLGDCIFETVQDTEAWNKYFAPLHCLNFSIRDDCTEHVLWRIENGALDNVNPKIVVLHVGTNNVRNSAEEVAEGVLANVTKIRQKLPNAYIVLPSLLPRGQQPNKLREKNAKINEVVNGLTKGLYRVQTVAIDKGLVQTDGSISHHDMFDYKNLTNAGAKKILEPLYDLLSQILNENEPENDLTPSE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **..:* . *::**.** * *.**: **::*:***:*:**.:.: :*: * *.: *:***.***.* .* *.*****::** *:*::**::*: ***** .*:***** *: * * *. : *:* *:: .*****::** **:****:*:::: * .** : * *:*::**:** *****: :**..* ** :**::*: *:*:*. *:: * : ", "identical_positions": 106, "similar_positions": 72, "identity": "46.09%" }, { "cls_id": "homologset.agr.RGD:620333", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35263-1", "uniprot_id": "PA1B3_RAT", "id": "O35263-1", "name": "Platelet-activating factor acetylhydrolase IB subunit alpha1", "aln": "MSGEGENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDSTQHVLWRLENGELEHIRPKIVVVWVGTNNHSHTAEQVTGGIKAIVQLVNKLQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGYPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGIPLPETAP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61205-1", "uniprot_id": "PA1B3_MOUSE", "id": "Q61205-1", "name": "Platelet-activating factor acetylhydrolase IB subunit alpha1", "aln": "MSGEGENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDSTQHVLWRLENGELEHIRPKIVVVWVGTNNHSHTAEQVTGGIKAIVQLVNKLQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGYPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGIPLPETAS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15102-1", "uniprot_id": "PA1B3_HUMAN", "id": "Q15102-1", "name": "Platelet-activating factor acetylhydrolase IB subunit alpha1", "aln": "MSGE-ENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZTU4-1", "uniprot_id": "Q7ZTU4_DANRE", "id": "Q7ZTU4-1", "name": "Platelet-activating factor acetylhydrolase IB subunit alpha1", "aln": "MSGD-SNPAATPTPCQDIQGDGRWMSLHNRFVSDSKGKEPDVLFVGDSLIQLLHEFEVWRKLFSPLHALNFGIGGDATQHVLWRLINGELDYISPKVVVLWVGTNNHGQTPEQICGGIMAIINVIHQKLPNSHTLVLGLLPRGKSPNPLRERNASVNALVQAEVASLSHVSFLNMDPGFVHSDGSIAHQDMYDYLHLTPHAYQRVCEPLHEHLKSLLEKH----------AP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXP4-1", "uniprot_id": "PA1B2_DROME", "id": "Q9VXP4-1", "name": "Platelet-activating factor acetylhydrolase IB subunit beta homolog", "aln": "-----MNPCVLPTPLPDLDGDKRWHSIHRRFISDCREKDPDVIFLGDCIFETVQDTEAWNKYFAPLHCLNFSIRDDCTEHVLWRIENGALDNVNPKIVVLHVGTNNVRNSAEEVAEGVLANVTKIRQKLPNAYIVLPSLLPRGQQPNKLREKNAKINEVVNGLTKGLYRVQTVAIDKGLVQTDGSISHHDMFDYKNLTNAGAKKILEPLYDLLSQILNENE----PENDLTPSE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. *** *::** ** *:*.**::*.: *:*:*:*:**.:.: ::: * *.: *:***.***.* .* *:*****: ** *: : **:**: ***** ::.*:: *: * : :.: *:: :: .*****: ** ***:* .:* :*.. . :. : * *:*::**:*:*:**:** :*: . : ..*:. * :* :. :. ", "identical_positions": 82, "similar_positions": 78, "identity": "35.04%" }, { "cls_id": "homologset.agr.RGD:620334", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LL66-1", "uniprot_id": "A0ABK0LL66_RAT", "id": "A0ABK0LL66-1", "name": "DNA fragmentation factor subunit alpha", "aln": "MELSRGASAPDPDDVGPLKPCLLRRNHSREQHGVAASSLEELRSKACELLAIDKSLTPVTLVLAEDGTIVDDEDYFLCLPSNTKFVALACNEKWAYNDSDGGTAWLSQESFDTDQTDSGAGVKWKNVARQLKEDLSSIILLSEEELQALIDIPCAELAQELCQSCATVQGLQSTLQQVLDQREEARQSKQLLELYLQALEKEGSILSNQNESKAALGEELDAVDTGVGGEVASEVMLRSQILAALKEKPAPELSLSSQDLESVSKEDPKALAVALSWDIKKAETVQQACTTELALRLQQVQSLHSLRNLSAKRKPLPGDPQSPKRAKVDFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54786-1", "uniprot_id": "DFFA_MOUSE", "id": "O54786-1", "name": "DNA fragmentation factor subunit alpha", "aln": "MELSRGASAPDPDDVRPLKPCLLRRNHSRDQHGVAASSLEELRSKACELLAIDKSLTPITLVLAEDGTIVDDDDYFLCLPSNTKFVALACNEKWIYNDSDGGTAWVSQESFEADEPDSRAGVKWKNVARQLKEDLSSIILLSEEDLQALIDIPCAELAQELCQSCATVQGLQSTLQQVLDQREEARQSKQLLELYLQALEKEGNILSNQKESKAALSEELDAVDTGVGREMASEVLLRSQILTTLKEKPAPELSLSSQDLESVSKEDPKALAVALSWDIRKAETVQQACTTELALRLQQVQSLHSLRNLSARRSPLPGEPQRPKRAKRDSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00273-1", "uniprot_id": "DFFA_HUMAN", "id": "O00273-1", "name": "DNA fragmentation factor subunit alpha", "aln": "MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQSLHSLRSISASKASPPGDLQNPKRARQDPT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:: .*..*:..:: .*********:**:*******.**:******::*********:*************:****************.**** **:*******:*****:.*:.** **:**********************:** *:* **::***** ******* ** ***********.*******:**********.:**:*:*****:.**:******:. * :*:* * *:**::*:** ************ *:***********.***:*:****:** ********.*******.:** : . **: * ****: * :", "identical_positions": 246, "similar_positions": 61, "identity": "74.32%" }, { "cls_id": "homologset.agr.RGD:620335", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54788-1", "uniprot_id": "DFFB_MOUSE", "id": "O54788-1", "name": "DNA fragmentation factor subunit beta", "aln": "MCAVLRQPKCVKLRALHSACKFGVAARSCQELLRKGCVRFQLPMPGSRLCLYEDGTEVTDDCFPGLPNDAELLLLTAGETWHGYVSDITRFLSVFNEPHAGVIQAARQLLSDEQAPLRQKLLADLLHHVSQNITAETREQDPSWFEGLESRFRNKSGYLRYSCESRIRGYLREVSAYTSMVDEAAQEEYLRVLGSMCQKLKSVQYNGSYFDRGAEASSRLCTPEGWFSCQGPFDLESCLSKHSINPYGNRESRILFSTWNLDHIIEKKRTVVPTLAEAIQ--DGREVNWEYFYSLLFTAENLKLVHIACHKKTTHKLECDRSRIYRPQTGSRRKQPARK----KRPARKR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99N34-1", "uniprot_id": "DFFB_RAT", "id": "Q99N34-1", "name": "DNA fragmentation factor subunit beta", "aln": "MCAVLPQPKCVKLRALHSSCKFGVAARSCQELLRKGCIRFQLPVPGSRLCMYEDGTEVTDDCFPSLPNDSELLLLTAGETWHGYVSDITRLLSVFNEPHAGVIQAARQLLSDEQAPLRQKLLADLLHHVSQNITAETREQDPSWFEGLESRFRNKSGYLRYSCESRIRGYLREVSAYISMVDAAAREEYLRVLSSMCHKLKSVQYNGSYFDRGAEASSRLCTPEGWFSCQGPFDLESCLSKHSINPYGNRESRILFSTWNLDHIIEKKRTVVPTLAEAIQ--DGREVNWEYFYSLLFTAENLKLVHIACHKKTTHKLQCDRSRIYRPQTGSRRKQPPRKQPPRKRPPRKRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76075-1", "uniprot_id": "DFFB_HUMAN", "id": "O76075-1", "name": "DNA fragmentation factor subunit beta", "aln": "---MLQKPKSVKLRALRSPRKFGVAGRSCQEVLRKGCLRFQLPERGSRLCLYEDGTELTEDYFPSVPDNAELVLLTLGQAWQGYVSDIRRFLSAFHEPQVGLIQAAQQLLCDEQAPQRQRLLADLLHNVSQNIAAETRAEDPPWFEGLESRFQSKSGYLRYSCESRIRSYLREVSSYPSTVGAEAQEEFLRVLGSMCQRLRSMQYNGSYFDRGAKGGSRLCTPEGWFSCQGPFDMDSCLSRHSINPYSNRESRILFSTWNLDHIIEKKRTIIPTLVEAIKEQDGREVDWEYFYGLLFTSENLKLVHIVCHKKTTHKLNCDPSRIYKPQTRLKRKQPVRK--------RQ--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :**.******:*. *****.*****:*****:***** *****:******:*:* **.:*:::**:*** *::*:****** *:**.*:**:.*:****:***.***** **:*******:*****:**** :**.*********:.**************.******:* * *. *:**:****.***::*:*:***********:..*****************::****:******.**********************::***.***: *****:*****.****:********.*********:** ****:*** :**** ** *: ", "identical_positions": 255, "similar_positions": 64, "identity": "72.65%" }, { "cls_id": "homologset.agr.RGD:620336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q767I8-1", "uniprot_id": "PCDA4_RAT", "id": "Q767I8-1", "name": "Protocadherin alpha-4", "aln": "MEFSWGSGQESQRLLLSFLFLAIWEPGNSQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPTFPTTQKNLFIAESRPLDTWFPLEGASDSDIGINAVLTYRLSPNDYFSLEKPTNSERVKGLGLILRKSLDREETPELFLVLTVTDGGKPELTGSVQLLITVLDANDNSPVFDRSLYTVKLPENVPNGTLVVKVNASDLDEGANGEVMYSFSTDISPNVKNKFHIDPVTGEIAVKGYIDFEECTSYEILIEGIDKGQLPLSGHCKVIVQVEDINDNAPELEFKSLSLPIRENAPVGTVIALISVFDPDTGVNGQVTCSLTPQVPFKLVSTFKNYYSLVLDSALDRETTADYKVVVIARDGGLPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGAHIFTVSAVDADSQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLEPEAGISGGIVSRLVSRSVGAGHVVAKVRAVDADSGYNAWLSYELQSSEGNSRSLFRVGLYTGEISTTRSLDEADSPRQRLLVLVKDHGDPAMMVTATVLVSLVENGPLPKAPSRVSTRVTNAEASLVDVNVYLIIAICAVSSLLVLTLLLYSALRCSTVPSESVCGPPKPVMVCSSAVGSWSYSQQRRQRVCSGEYPPKTDLMAFSPSLS---DSRDREDQLQSTEDSSGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQPGPGELPDKFIIPGSPAIISIRQESANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5H8-1", "uniprot_id": "PCDA3_HUMAN", "id": "Q9Y5H8-1", "name": "Protocadherin alpha-3", "aln": "MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *** .. :* ****:*:** * *..*****:.********************************* :****************************************************:*****.*.** : *****:*** .: *.******:*** *::*** *...:**:*: *.*.:*.***:*:*.*:**:**: :*::*. *********:.** *****.***:*.*:*::*.*:* **.*******.***:*****.* :: ***.**:*.:: .***:***.*:*:*** *****..**** :*. ***: *:*.**.*:::: *****.*** ::*****: *::*:.******** * *:************:*******************.****:.: *::** ***** ***********************:*.*************.******* ***:****************** **************:*************************.*******************:** *..* ** **.**.******************************.. *.:* **************:***.*:**:**********:*:: .**********.* ***.*:.*: .*..**:*********:****************:*****: *:*. *** **.:***************:******* ************. *****:: : * *.*********************************************************************************.***********************.:*.********************************************", "identical_positions": 741, "similar_positions": 144, "identity": "78.0%" }, { "cls_id": "homologset.agr.RGD:620337", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8N7UY30-1", "uniprot_id": "A0A8N7UY30_DANRE", "id": "A0A8N7UY30-1", "name": "", "aln": "----MALTRTHVLRSWIFFSVFLCCWIFTNGQIVYSISEEANPGTAVGNLAKDFNLNVQDIERRGFQIVSESNKRYFDFNFKTGVLHVKERIDREELCEQKIKCSLPLEAIVNSPLNVFRFEINVLDINDNPPKFRTPKTTINISESALPGEQFALPSAFDADVGINSVKSYKLSPNEHFSLDVQSGGEQSVSAELVLQKALDREKQPLIRLTLTAVDGGKPLRSGTMQITVHVEDVNDNIPVFSKSLYKARVNENAPPGTSIITVQASDPDEGVNGQIVYALVNHD-NDRNVESFAINPETGEITVKGDVDYERKNAVELRVQAKDKGHKPRAALCKVLLEIIDVNDNVPEISVTSLVNTVKEDALIDTVVGMITVTDNDAGKNGQVILNIQGSSPFKVQNS-YKNYYTLFVNGPLDRERASEYNVTISAADEGTPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNN--LFRIGTSSGEIRTKRRMSDNDLKTHPLVVLVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLIGLIAVKCHRT--DSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3Y6-1", "uniprot_id": "A0A8M1N3Y6_DANRE", "id": "A0A8M1N3Y6-1", "name": "", "aln": "----MAIVPLHNCLSVILFYVVFCFGSTAEGHIVYTVSEETNPGTTVGNLAKDLNLNLQDITNRGFQLVSGANKRYFELNSKTGFLHINDRIDRDELCGRSLKCSFPLEAIVNAPLNVYRFEVSIIDINDNSPTFRSPVKYFNISESAFPGERFPLPTAFDADVGSNSVKSYKLSANEHFSLDVQSGGEQSVSAELVLQKALDREKQPVIKLTLTAVDGGKPPRSGTINIIVNIEDVNDNIPVFSKPLFKTRVVENSPFGTSVIQVHASDPDEGPNSEIVYSLLSQD-NENNADAFAIDPETGVITVKGTVDYEKNAAVEIRVQAKDKGHKPRAAYCKVLVEITDINDNTPEISVTSLVNTVKEDAANGTVVSMITVLDNDAGKNGEIQLKIRDSLPFKVQNS-YKNYYTLIVNGHLDRETASEYNVTISAADEGTPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNN--LFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHRT--DSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3N1-1", "uniprot_id": "A0A8M1N3N1_DANRE", "id": "A0A8M1N3N1-1", "name": "", "aln": "MGVNMDISEDRWSFYWICIVVFLTNWNYADGQIVYSVSEEVNTGTTVGNLAKDLNLNVQDLERRGFQIVSGPNKQYFDLHARNGILFVRERIDREELCGRSSKCALELEAIVSAPMSIYRFEVNILDVNDNAPTFRTSKLFLNISEQTYPGQRFTLPSAFDLDAGVNSVKSYKLSANEHFSLDVQSAGDQSVSAELVLQKALDREKQPVIRLTLTAVDGGKPPMSGTTQIIVNVVDVNDNIPVFDKPLYKARIAENSAIGASVITVSAKDADEGLNGEVIYSFINHD-NENSINAFLINPNTGEITVKGPLDYEENAAIEIRVQAEDKGQNPRASHCKVLIEIIDLNDNTPEISIMSLVNEVKEDSAPGTMVGLITVKDGDAGKNGVVRLQIRDSAQFRLENT-YKNRFSLVVNGPLDREVASEYNVTISAADEGTPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNN--LFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHRT--DSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3N4-1", "uniprot_id": "A0A8M1N3N4_DANRE", "id": "A0A8M1N3N4-1", "name": "", "aln": "---MFSMHRRRSVVACFVLVVLVCFWDAASGQLSYSVSEEVSPGTTVGNLAKDLNLNVQELESRMFQIVTGAKKKYFEVNLKTGFLYVNERIDREELCAKAPKCTVSVEAVINNPLKLYQIEINIVDVNDNKPTFNSKTQYLDVAENTLPGVKFPLSYASDADVGKNTVSTYKLSQNEYFSLAVHKGEEQSVSAELVLQKALDREKQPLVQLTLTAADGGNPPKSGTSQIIIRVLDINDNAPVFSRPLYKASLVENVPIGSTVIIINATDKDEGTNSDIIYSLRETD-QDHILDIFQIDAITGAITVKGDVNFEKNNAFEIRAQASDKGQPPMSTHCKVLVEVLDINDNEPEITVTSLLSTVKEDASIGTAVALVSVIDRDGGRNGVVNCAVSNNVPFKLQTN-YKNYYSLVVDGPLDRERASEYNVTISAADEGSPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLE-SSKSGPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNN--LFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHRT--DSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3Y1-1", "uniprot_id": "A0A8M1N3Y1_DANRE", "id": "A0A8M1N3Y1-1", "name": "", "aln": "------MAHIIVMSGIVICLVLLLLMPSASAQVAYSISEEANTGTFVGNIAKDLNLNIQELESRGFHIPAVSGRKYFEVNLKTGVLFVSERIDREAFCPASPQCSVNLEAIVNNPLNLFRIEINIVDINDNSPSFRVRSMHINVSEYAFIGDRFQLPRASDPDVGANSVKSYKLSPNEHFSLDVQSGGEQSASAELVLQKALDREKQPAIHLTLTAVDGGKPPKSGTMQIAIHVQDVNDNAPVFGKALYKVRIVENAPLGTLVINLNATDLDEGLNSEIIYSLVQQDSDDKASSVFKIDSATGVVSMQGRVDFEERNAYEIHAQAKDKGASPRSAHCKILVEVLDVNDNEPEISLTSQVNTVREDAKRETTVALITISDKDSGKNGNVHGKVVGDVPFKLQSS-YKNYYSLVVDEPLDRERVDRYNVTIMASDEGAPPLSATRVFTVYVSDVNDNPPSFPNPVINVFVKENGPMDQIIYTLSAVDPDLNENSKITYGLLEPLHKSGSTYSAITINSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVN-TENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNN--LFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHAP---VKEESFSDLNLYLLIAIVSVSVIFLLSLISLIAVKCHRT--DSSLGRYSAPMITTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVFPAPFPPADAELISINGGDTFTRTQTLPNKEKPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N3X5-1", "uniprot_id": "A0A8M1N3X5_DANRE", "id": "A0A8M1N3X5-1", "name": "", "aln": "---MANENTRTWMSRIFYLMCLLFNSGGKAAQINYSLQEESKIGVNVGNIAKDLGIDPTSLENRNFRIVVGTKQELFRVNHEDGALFVSQRIDREELCAKINPCLINLKAVIENPLEMHQISVDIIDVNDNPPSFLDENYKLEILESAMTGARFQVETAHDPDIGSNDLQSYKLSQNHYFRLETEDMGDEGKIPVLILQKPLDREKSARHNLILTATDGGKPHKSAAANITIVVSDVNDNTPVCDKQKYTVTVKEDAPEGTFLLRVNASDSDEGVNGEIEYSLRNKF-RKGASDVFDLDNITGELKIKGGLNFEERQVYELKILAADKGAVSLSTQCNVLVNVEDVNDNRPEIDVTSLSSHIPEDAAPGTVVALIGVTDLDSGMNGKIICSLPKNIPFDLKPSPDGNFYSLVTKENIDKEAKSSYDITITAKDLGSPSLSSTRSIHVEVTDVNDNSPKFAQSPYTFYVTENNKPGIAVFSLSASDLDEGENARVSYTIDR-INSDQSMTSFLSINEANGTVYSLKSFDFESLKTFHFFVVAKDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSEHS--LFALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNVSLSATATVIVKVVEPKEAFAASDVKNA---VKDKEENNVTFYLIITLGSVSVLFVISIIVLIVMQCSKS--TDYSSKY---LQDTNYDGTLCHSIQYRSGDKRYMLVGPRMSIGSTIAPGS---------NRNTLVIPDRRRRDSGEPKVPSSDWRYSASLRAGMQSSVRMEESSVMQGAQGVLVQNWPTVSSA-PDNEGGEVSPPVGAGVDSNSWHFRYGPGPGGPPHLKPGEVPPEAFIIPGSPAIISIRQ--GQDGDDKSDFITFGKKEEAKKLKKKKKKEKK-DKREKGKDDDD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q767I8-1", "uniprot_id": "PCDA4_RAT", "id": "Q767I8-1", "name": "Protocadherin alpha-4", "aln": "--MEFSWGSGQESQRLLLSFLFLAIWEPGNSQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPTFPTTQKNLFIAESRPLDTWFPLEGASDSDIGINAVLTYRLSPNDYFSLEKPTNSERVKGLGLILRKSLDREETPELFLVLTVTDGGKPELTGSVQLLITVLDANDNSPVFDRSLYTVKLPENVPNGTLVVKVNASDLDEGANGEVMYSFSTDI-SPNVKNKFHIDPVTGEIAVKGYIDFEECTSYEILIEGIDKGQLPLSGHCKVIVQVEDINDNAPELEFKSLSLPIRENAPVGTVIALISVFDPDTGVNGQVTCSLTPQVPFKLVST-FKNYYSLVLDSALDRETTADYKVVVIARDGGLPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGAHIFTVSAVDADSQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLEPEAGISGGIVSRLVSRSVGAGHVVAKVRAVDADSGYNAWLSYELQSSEGNSRSLFRVGLYTGEISTTRSLDEADSPRQRLLVLVKDHGDPAMMVTATVLVSLVENGPLPKAPSRVSTRVTNAEASLVDVNVYLIIAICAVSSLLVLTLLLYSALRCSTVPSESVCGPPKPVMVCSSAVGSWSYSQQRRQ-RVCSGEYPPKTDLMAFSPSLSD------SRDREDQLQSTED--SSGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPG--NPKQPGPGELP-DKFIIPGSPAIISIRQESANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88689-1", "uniprot_id": "PCDA4_MOUSE", "id": "O88689-1", "name": "Protocadherin alpha-4", "aln": "--MEFSWGSGQESQRLLLSFLLLAIWEAGNSQIHYSIPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPRFPTTQKNLFIAESRPLDTWFPLEGASDADIGINAVLTYRLSPNDYFSLEKPSNDERVKGLGLVLRKSLDREETPEIILVLTVTDGGKPELTGSVQLLITVLDANDNAPVFDRSLYTVKLPENVPNGTLVVKVNASDLDEGVNGDIMYSFSTDI-SPNVKYKFHIDPVSGEIIVKGYIDFEECKSYEILIEGIDKGQLPLSGHCKVIVQVEDINDNVPELEFKSLSLPIRENSPVGTVIALISVSDRDTGVNGQVTCSLTSHVPFKLVST-FKNYYSLVLDSALDRETTADYKVVVTARDGGSPSLWATASVSVEVADVNDNAPVFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLRFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLEPEAGVSGGIVSRLVSRSVGAGHVVAKVRAVDADSGYNAWLSYELQSSEGNSRSLFRVGLYTGEISTTRILDEADSPRQRLLVLVKDHGDPAMIVTATVLVSLVENGPVPKAPSRVSTSVTHSEASLVDVNVYLIIAICAVSSLLVLTLLLYTALRCSTVPSESVCGPPKPVMVCSSAVGSWSYSQQRRQ-RVCSGEYPPKTDLMAFSPSLSD------SRDREDQLQSAED--SSGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPG--NPKQSGPGELP-DKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UN74-1", "uniprot_id": "PCDA4_HUMAN", "id": "Q9UN74-1", "name": "Protocadherin alpha-4", "aln": "--MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDI-SPNVKSKFHIDPITGQIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVST-FKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRP-RVCSGEGPPKTDLMAFSPSLPD------SRDREDQLQTTEE--SFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPG--NPKQSGPGELP-DKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. .:: *:: ** . *. **.:*:*:.:: .: * *:: : .: . * *.: .****: :* * . ::.::. *:.:.:..:.: *:*** * * : : * . * : * * * * * : :*:** *.:* * : *:*:*.****: . * **..***:* :.: :: : : * *** *. .: :.. : *: . *: :: : *.* *** *.:: *:: * :: :* : ::* :::*. *: . *** . : *.::::: * *** *:: . * : *:: * :.:: : * * * ** : : * : . * ::*. . :*:* *.:.: * * * *.* :* . * *:*****.* *.:. ..:*.**. . :.::** * * :*: ::* : . . * :.:: .* :.:*:.::.*.:: :.* * * *:* *.*.****::**:**:*** *.:* * : . . :. .. .*:.*:*:** *** ***. * : :. * :. :*:* * * : : * : *::** *:*: :: .*.:: . :** :. : ::..**:*:: :** ::::::: .::* . . : : *: .:* . : : .: .. . : . . . :*: *..************:***::**:.:::.. * *:******* *: *.***********:**** *:**** .* : ***:* : ************** :. *************:** ***** :*. :*:***:. * ", "identical_positions": 272, "similar_positions": 296, "identity": "28.25%" }, { "cls_id": "homologset.agr.RGD:62034", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07984-1", "uniprot_id": "SSRD_RAT", "id": "Q07984-1", "name": "Translocon-associated protein subunit delta", "aln": "MAAMASFGALALLLLSGLSCCSAEACLEPQITPSYYTTSDAVISTETVFIVEISLTCKNRVQNMALYADVSGKQFPVTRGQDVGRYQVSWSLEHKSAHAGTYEVRFFDEESYSLLRKAQRNNEDVSIIPPLFTVSVDHRGTWNGPWVSTEVLAAAIGIVIYYLAFSAKSHIQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62186-1", "uniprot_id": "SSRD_MOUSE", "id": "Q62186-1", "name": "Translocon-associated protein subunit delta", "aln": "MAAMASFGALALLLLSGLSCCS-EACLEPQITPSYYTTSDAVISTETVFIVEISLTCKNRVQNMALYADVSGKQFPVTRGQDVGRYQVSWSLEHKSAHAGTYEVRFFDEESYSLLRKAQRNNEDVSIIPPLFTVSVDHRGTWNGPWVSTEVLAAVIGIVIYYLAFSAKSHIQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51571-1", "uniprot_id": "SSRD_HUMAN", "id": "P51571-1", "name": "Translocon-associated protein subunit delta", "aln": "MAAMASLGALALLLLSSLSRCSAEACLEPQITPSYYTTSDAVISTETVFIVEISLTCKNRVQNMALYADVGGKQFPVTRGQDVGRYQVSWSLDHKSAHAGTYEVRFFDEESYSLLRKAQRNNEDISIIPPLFTVSVDHRGTWNGPWVSTEVLAAAIGLVIYYLAFSAKSHIQA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*********.** ** ***********************************************.*********************:*******************************:*****************************.**:***************", "identical_positions": 164, "similar_positions": 7, "identity": "94.8%" }, { "cls_id": "homologset.agr.RGD:620340", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35921-1", "uniprot_id": "EAA4_RAT", "id": "O35921-1", "name": "Excitatory amino acid transporter 4", "aln": "MSSHGNSLFLRESGAGG---GCLQGLQDSLQQRALRTRLRLQTMTREHVRRFLRRNAFILLTVSAVIIGVSLAFALR--PYQLTYRQIKYFSFPGELLMRMLQMLVLPLIVSSRVTGMASLDNKATGRMGMRAAVYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVP---TADAFMDLVRNMFPPNLVEACFKQFKTQYSTRVVTRTIVRTDNGSELGASISPPSSAENETSILENVTRALGTLQEVISFEETVPVPGSANGINALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFPFIGGILQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQRELE----LQEAELTLPSLG---KPYKSLMAQAKGAS-RGRGGNESVM------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35544-1", "uniprot_id": "EAA4_MOUSE", "id": "O35544-1", "name": "Excitatory amino acid transporter 4", "aln": "MSSHGNSLFLRESGAGG---GCLQGLQDSLQQRALRTRLRLQTMTREHVRRFLRRNAFILLTVSAVIIGVSLAFALR--PYQLSYRQIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASLDNKATGRMGMRAAVYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVP---TADAFMDLVRNMFPPNLVEACFKQFKTQYSTRVVTRTIVRTDNGSELGASMSPTSSVENETSILENVTRALGTLQEVISFEETVPVPGSANGINALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFPFIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQRELE----LQEAELTLPSLG---KPYKSLMAQEKGAS-RGRGGNESVM------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48664-1", "uniprot_id": "EAA4_HUMAN", "id": "P48664-1", "name": "Excitatory amino acid transporter 4", "aln": "MSSHGNSLFLRESGQRLGRVGWLQRLQESLQQRALRTRLRLQTMTLEHVLRFLRRNAFILLTVSAVVIGVSLAFALR--PYQLTYRQIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASLDNKATGRMGMRAAVYYMVTTIIAVFIGILMVTIIHPGKGSKEGLHREGRIETIP---TADAFMDLIRNMFPPNLVEACFKQFKTQYSTRVVTRTMVRTENGSEPGASMPPPFSVENGTSFLENVTRALGTLQEMLSFEETVPVPGSANGINALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIVGLFLHAGIVLPLIYFLVTHRNPFPFIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQRELE----LQEAELTLPSLG---KPYKSLMAQEKGAS-RGRGGNESAM------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A6H2EJK0-1", "uniprot_id": "A0A6H2EJK0_DROME", "id": "A0A6H2EJK0-1", "name": "Amino acid transporter", "aln": "--------MTRPKQDGG------------------------------KFKAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASKVLTPDTLMDLVRNMFTDNIIQSTMFQHRTEIY-----------EN-----TSISPAQPMEN---------------WEFKSAQR--------EGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCLDN-MGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLSKNDLASVDRLNAEPHELLELGPNGHEMKEXRQSSLGAYNRKRXVDMSRLWACFHILPSNDSDSDDYDDDDEEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . :. *::.*.: : ** .*.:* :.* :: . : : *:* *:*****:::***: *::**:*** .:.:..** . :.::. ** .**:***: **::** :** ::**:*:* : *:. . *.*::***:****. *:::: : *.:*: :* :*:.*. . ** *. * :. :* *.****:*** :* .** *:.**::*:*** :*.**:* :.. :** :*:*: ****.**:***.:*. .** * :**::*****. .:.:*:** *:* *: :*. : *.* **:**.*****:*:*::**:: :*:* *:****:*****:**********:**:**** .: . .:* *.::********:**************:** :*** .:*::*******:***:** **: *::*: :::***:.:* *: * .** : *. . ** * * : * : ", "identical_positions": 221, "similar_positions": 167, "identity": "36.77%" }, { "cls_id": "homologset.agr.RGD:620341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920Q0-1", "uniprot_id": "PALM_RAT", "id": "Q920Q0-1", "name": "Paralemmin-1", "aln": "MEVLATDTVSQQERLQAIAEKRRKQAEIESKRRQLEDDRRQLQYLKSKALRERWLLEGTPSSASEGDEDMRKQMQEDEQKARSLEESITRLEKEIDVLEFGESAPAAPKENSAAPSPIRPHSTSPAKEEQKSETMVNAQQTPLGTPKENRKS-TPVRSPGGSTMMKAAMYSVEITVEKDKVTGETRVLSSTTLLPRDPLPQGVKVYEDETKVVHAV---DGLSENGIQPLSSSEVDELIHKADEVTLSEAGSTTGPAEPRGLAEDVTR----TTPSRR------EITGVEAQPGEATSGPPGIQPGQEPPVTMVFMGYQNVEDEAETKKVLGLQDT-IKAELVVIED-------SVTPREPAPLNGSAAELP---ATKEENQTGPTTTPSDTQDLDMK-KPRCRCCSVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0P4-1", "uniprot_id": "PALM_MOUSE", "id": "Q9Z0P4-1", "name": "Paralemmin-1", "aln": "MEVLATDTASQQERLQAIAEKRRKQAEIESKRRQLEDDRRQLQYLKSKALRERWLLEGTPSSASEGDEDMRKQMQEDEQKARGLEESITRLEKEIDVLEFGESAPAASKENSAAPSPGRPQSASPAKEEQKSETLVNAQQTPLGTPKENRTS-TPVRSPGGSTMMKAAMYSVEITVEKDKVTGETRVLSSTTVLPRDPLPQGVKVYEDETKVVHAV---DGIAENGIQPLSSSEVDELIHKADEVTLSEAGSTAGPAEPRGLAEDVTR----TTPSRR------EITGVEAQPGEATSGPPGIQPGQEPPVTMVFMGYQNVEDEAETKKVLGLQDT-IKAELVVIED-------AATPREPAPLNGSAAELP---ATKEENQTGPTTTPSDTQDLDMK-KPRCRCCSVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75781-1", "uniprot_id": "PALM_HUMAN", "id": "O75781-1", "name": "Paralemmin-1", "aln": "MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAV---DGTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAAR----TTPSRR------EITGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDT-ITAELVVIED-------AAEPKEPAPPNGSAAEPPTEAASREENQAGPEATTSDPQDLDMK-KHRCKCCSIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2U8-1", "uniprot_id": "A0A8M2B2U8_DANRE", "id": "A0A8M2B2U8-1", "name": "Paralemmin-1", "aln": "--MEMSESVSQQERLQAIAEKRKRQTEIENKKRQLEDDRRQLQHLKSKALRERWLLDGAPSAGQEEDE-TTKQLREHEAKTRGLEETIVSLERELEELETGVSATST-KEN-----------LSDALQEINTKTVEKMVVTESVKEVKVHVSPRLEKSGGVSDMMRAAMYSVEITVEKDLVTGETKVLSTNTLLPKDLSQQGVKVYEDEQKVVHEVRSVDGTVTNGVHQLSSSEVDELLHKADEVTMGESSKTTPRLE-RGQAEKEEKHEKDVTPAEASSTPIMEITGVEAKPAAPQTEVSGAS--AENPVTMVFMGYQSVEDEDETKKVLGMESTTVKAEVVLIEDGEGKNAGSDTKQEQAPPNGSPAEAD----KAEEAARESEQPEGDNAEVKSKEKQPCKCCTIM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::.*************::*:***.*:*****:*****:************:*:**:..* ** :*:::.* *:* **::: **:*:: ** * **.:: *** * * :* :::.: : * . . : * :: . * **:************* *****:***:.*:**:: *:****** **** * ** **:: *********:*******:.*:..*: * ** .* : .**:. *****:*:*. . : .* . * ****:*****.**** *******::.* :.**:*:*** : :* ** ***.** . ** . . .* ::. * * *:**::*", "identical_positions": 188, "similar_positions": 96, "identity": "45.97%" }, { "cls_id": "homologset.agr.RGD:620342", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54880-1", "uniprot_id": "RPH3L_RAT", "id": "O54880-1", "name": "Rab effector Noc2", "aln": "MADTIFSSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRTQCLSPGEVEVILQVIQRAERLDILEQQRIGRLVERLETMQKNVMGNGVSQCLLCGEMLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPLPVEPTEPQPQSAEVSRVYTWARGRVVSSDSDSDSDLSSSSLEDRPMPSGIKGTKYDKPRGDSGGSMESPRMGPARPPSHLSGSQSSLGS-ETGAGATDPQGGTLPRPEPRVSGKRHTWATTHY------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q768S4-1", "uniprot_id": "RPH3L_MOUSE", "id": "Q768S4-1", "name": "Rab effector Noc2", "aln": "MADTIFSSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRSQCLSPGELEIILQVIQRAERLDILEQQRIGRLVERLETMQRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPLPVEPTETQPPSAETSRVYTWARGRVVSSDSDSDSDLSSSSLEDRPLPSGVKGTKGDKPRGDSGASMESPRLGPARPPSHLSGSQSSLGS-EAGTGATEPQGGTPAQPEPRVPGKRHTWATPRY------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNE2-1", "uniprot_id": "RPH3L_HUMAN", "id": "Q9UNE2-1", "name": "Rab effector Noc2", "aln": "MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRKQHLSPAEVEAILQVIQRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSSCLG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.************************************.* ***.*:* ************:****************::******:********:********************************************************************************.**:* :* *:*.**:*************************** .:*::. * *** :**.*:*:**:* ::**.****.****.* *:*:*:::* **. . *.. * . :. ", "identical_positions": 236, "similar_positions": 42, "identity": "74.92%" }, { "cls_id": "homologset.agr.RGD:620344", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64277-1", "uniprot_id": "BST1_MOUSE", "id": "Q64277-1", "name": "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2", "aln": "MAVQGGLLSLWLWLWLSLLTVLLG------ARARWRGEGTTPHLQSIFLGRCAEYTTLLSL--GNKNCTAIWEAFKGVLDKDPCSVLPSDYDLFINLSRHPIPRDKSLFWENNHLLVMSYGENTRRLVALCDVLYGKVGDFLSWCRQENASGLDYQSCPTSEDCENNAVDSYWKSASMQYSRDSSGVINVMLNGSEPKGAYPTRGFFADFEIPYLQKDKVTRIEIWVMHDVGGPNVESCGEGSVKILEDRLEALGFQHSCINDYRPVKFLMCVDHSTHPDCIMNSASASMRRESASLHAIGDASLLISLLVALASSSQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63072-1", "uniprot_id": "BST1_RAT", "id": "Q63072-1", "name": "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2", "aln": "MAVQACALSLRLGLWMSLLLPVLPGAGARAAGARWSGEGTTPHLQSIFLGRCAEYTTLLSLEPGNKNCTAIWEAFKVVLDKDPCSVLPSDYDLFINLSRHAIPRDKSLFWENNHLLVMSYAENTRRLMPLCDVLYGKVGDFLSWCRQENASGLDYQSCPTAEDCENNAVDAYWKSASMQYSRDSSGVINVMLNGSEPKGAYPTKGFFADFEIPYLQKDKITRIEIWVMHEVGGPHVESCGEGSVKILEDRLEALGFQHSCINDYPPVKFLMCVDHSTHPDCAMNSASASMWRESPALHAIGDISLIISLLVALASSSQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q10588-1", "uniprot_id": "BST1_HUMAN", "id": "Q10588-1", "name": "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2", "aln": "MAAQGCAASRLLQLLLQLLLLLLLLAAG-GARARWRGEGTSAHLRDIFLGRCAEYRALLSPEQRNKNCTAIWEAFKVALDKDPCSVLPSDYDLFINLSRHSIPRDKSLFWENSHLLVNSFADNTRRFMPLSDVLYGRVADFLSWCRQKNDSGLDYQSCPTSEDCENNPVDSFWKRASIQYSKDSSGVIHVMLNGSEPTGAYPIKGFFADYEIPNLQKEKITRIEIWVMHEIGGPNVESCGEGSMKVLEKRLKDMGFQYSCINDYRPVKLLQCVDHSTHPDCALKSAAAATQRKAPSLYTEQRAGLIIPLFLVLASRTQL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*. * * * :.** :* * *** ****:.**:.********* :*** ************ .**********************.***********.**** *:.:****::.*.*****:*.********:* **********:******.**::** **:***:******:********.**** :*****:*** ***:*:*********::***:********:*:**.**: :***:****** ***:* ********** ::**:*: *::.:*:: .*:*.*::.*** :* ", "identical_positions": 216, "similar_positions": 62, "identity": "67.71%" }, { "cls_id": "homologset.agr.RGD:620346", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K0C5-1", "uniprot_id": "ZG16_MOUSE", "id": "Q8K0C5-1", "name": "Zymogen granule membrane protein 16", "aln": "MLAVALLVLLCASASANSIQSRTSSYSGEYGGKGGKRFSHSGNQLDGPITAFRIRVNRYYIVGLQVRYGTVWSDYVGGTQGDLEEIFLHPGESVIQVSGKYKSYVKQMIFVTDKGRYLPFGKASGTSFNAVPLHPNTVLRFISGRSGSAIDSISLHWDTYPSHCNTC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CJD3-1", "uniprot_id": "ZG16_RAT", "id": "Q8CJD3-1", "name": "Zymogen granule membrane protein 16", "aln": "MLAIALLVLLCASASANSIQSRSSSYSGEYGGKGGKRFSHSGNQLDGPITAIRIRVNRYYIIGLQVRYGTVWSDYVGGNQGDLEEIFLHPGESVIQVSGKYKSYVKQLIFVTDKGRYLPFGKDSGTSFNAVPLHPNTVLRFISGRSGSAIDAISLHWDTYPSHCNTC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60844-1", "uniprot_id": "ZG16_HUMAN", "id": "O60844-1", "name": "Zymogen granule membrane protein 16", "aln": "MLTVALLALLCASASGNAIQARSSSYSGEYGGGGGKRFSHSGNQLDGPITALRVRVNTYYIVGLQVRYGKVWSDYVGGRNGDLEEIFLHPGESVIQVSGKYKWYLKKLVFVTDKGRYLSFGKDSGTSFNAVPLHPNTVLRFISGRSGSLIDAIGLHWDVYPSSCSRC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::***.*******.*:**:*:********* ******************:*:*** ***:*******.******** :********************** *:*:::*********.*** ************************* **:*.****.*** *. *", "identical_positions": 138, "similar_positions": 21, "identity": "82.63%" }, { "cls_id": "homologset.agr.RGD:620348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2IBC5-1", "uniprot_id": "CAV2_RAT", "id": "Q2IBC5-1", "name": "Caveolin-2", "aln": "MGLETEKADVQLFMADDAYSHHSVVDYTDPEKYVDSSQDRDPHQLNSHLKLGFEDLIAEPPTTHSFDKVWICSHALFEISKYVIYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLPSVQTIWKSVTDVVIGPLCTSVGRIFSSVSMQLSHD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVC3-1", "uniprot_id": "CAV2_MOUSE", "id": "Q9WVC3-1", "name": "Caveolin-2", "aln": "MGLETEKADVQLFMADDAYSHHSGVDYADPEKYVDSSHDRDPHQLNSHLKLGFEDLIAEPETTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLPSVQTIWKSVTDVVIGPLCTSVGRSFSSVSMQLSHD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51636-1", "uniprot_id": "CAV2_HUMAN", "id": "P51636-1", "name": "Caveolin-2", "aln": "MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEPVTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************** **:***** ::*:****:.**.:*****:***********:**** **********************:*******************************************************:*.******** *****:***:*", "identical_positions": 143, "similar_positions": 15, "identity": "88.27%" }, { "cls_id": "homologset.agr.RGD:620349", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35355-1", "uniprot_id": "PGH2_RAT", "id": "P35355-1", "name": "Prostaglandin G/H synthase 2", "aln": "MLFRAVLLCAALALSHAANPCCSNPCQNRGECMSIGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRNSIMRYVLTSRSHLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGTNMMFAFFAQHFTHQFFKTDQKRGPGFTRGLGHGVDLNHVYGETLDRQHKLRLFQDGKLKYQVIGGEVYPPTVKDTQVDMIYPPHVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYTFKQFLYNNSILLEHGLAHFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYHDIDAMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFRIINTASIQSLICNNVKGCPFASFNVQDPQPTKTATINASASHSRLDDINPTVLIKRRSTEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05769-1", "uniprot_id": "PGH2_MOUSE", "id": "Q05769-1", "name": "Prostaglandin G/H synthase 2", "aln": "MLFRAVLLCAALGLSQAANPCCSNPCQNRGECMSTGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRSLIMKYVLTSRSYLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPGFTRGLGHGVDLNHIYGETLDRQHKLRLFKDGKLKYQVIGGEVYPPTVKDTQVEMIYPPHIPENLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYSFKQFLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYSDIDVMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTSFNVQDPQPTKTATINASASHSRLDDINPTVLIKRRSTEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35354-1", "uniprot_id": "PGH2_HUMAN", "id": "P35354-1", "name": "Prostaglandin G/H synthase 2", "aln": "MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **:****.*.**::******:****** *** *******************:**********:*****************.**:********. ** *******:*********..**********************.******:****:*:****:*::**:****:*******:*******************:****.**.**********:***** **:*****:***:***:*.**:*********.:*****::**:*:******************************:********.**:*****************************************:*********:****************:*.**:*.::**:**********:::******************** *** *::*******:*****:******* **** ***********:***:*** ***.:***********************:************ **** *************:********************:**.* **: **.*****:*:* *********:*.*****", "identical_positions": 514, "similar_positions": 73, "identity": "85.1%" }, { "cls_id": "homologset.agr.RGD:62035", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61470-1", "uniprot_id": "CD37_MOUSE", "id": "Q61470-1", "name": "Leukocyte antigen CD37", "aln": "MSAQESCLSLIKYFLFVFNLFFFVLGGLIFCFGTWILIDKTSFVS-FVG--LSFVPLQTWSKVLAVSGVLTMALALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRVRLERRVQELVLRTIQSYRTNPDETAAEESWDYAQFQLRCCGWQSPRDWNKAQ----MLKANESEEPFVPCSCYNSTATNDSTVFDKLFFSQLSRLGPRAKLRQTADICALPAKAHIYREGCAQSLQKWLHNNIISIVGICLGVGLLELGFMTLSIFLCRNLDHVYDRLARYR------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31053-1", "uniprot_id": "CD37_RAT", "id": "P31053-1", "name": "Leukocyte antigen CD37", "aln": "MSAQESCLSLIKYFLFVFNLFFFVLGGLIFCFGTWILIDKTSFVS-FVG--LSFVPLQTWSKVLSVSGVLTMALALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRVRLERRVQELVLRTIQSYRTNPDETAAEESWDYAQFQLRCCGWQSPRDWNKAQ----MLKANGSEELFVPCSCYNSTATNDSSGFDKLFLSQLSRLGPRAKLRQTADICALPAKAHIYREGCARSLQKWLHNNIISIVGICLGVGLLELGFMTLSIFLCRNLDHVYDRLARYR------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11049-1", "uniprot_id": "CD37_HUMAN", "id": "P11049-1", "name": "Leukocyte antigen CD37", "aln": "MSAQESCLSLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVS-FVG--LAFVPLQIWSKVLAISGIFTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKYGTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVL----ILRGNGSEAHRVPCSCYNLSATNDSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLISIVGICLGVGLLELGFMTLSIFLCRNLDHVYNRLARYR------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GUH5-1", "uniprot_id": "A0AC58GUH5_DANRE", "id": "A0AC58GUH5-1", "name": "Tetraspanin", "aln": "-MASECCVSVTKYFLFLFNLVFFLLGSLLLSSGLWMLLSDTSEIKTFIDPFRPYISISLLSYLLIISGSVTMSLGFFGCLGSLKTVKFLLAIYFILLTVLLAAQIVGGVLFYTMKTELSKSLGKETD-LIQSFGRN--DSSFKKTMDYIQRQEECCGWNGKEDWGDSIPCSCYHKANETKELCDNCSPDFFYPVLSCKIYDEGCKDKVENWLGSNLHFILWVILAISVVECLQWTCVIFYCCFNRTHRCCPRESHGSHVQLSRFLFVTSVVFLFVTRVFHYCMPR---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KH03-1", "uniprot_id": "A0A0B4KH03_DROME", "id": "A0A0B4KH03-1", "name": "Tetraspanin", "aln": "-MGLNGCCSCVKYLMVLINILFWLIGLTIVVTSVWMLTDPTFMLSMTQN----YNHYHIALYVFLAIGILITLGAFFGCCGVCRESQCLLVSFFCVILIVMVAQIAAGAWAFHNKDKLDDIVRAAVKSSVQEEYGQSTMSSRTVTFDTLQKNLKCCGADGPGDWATSR----FNNVDRTNIVEIAVSSMNVFYNIPESCCKDNLKDNECELSRRLKFGG-------PLNNAIYQQGCVDKLIEIIYENWVTIFAVTAAVILLELLSLTFALSLCCAVRNQHYKAXELQNSHREITDDEKY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * **::.::*:.*:::* :. . *:* . * :. . : :: * . .::** * : : ** :* :: :::.:**. * : .*. : . :*. : :: : * * : .*** . ** . : :: * . .. : . . : .. . . * * .: :* : * : ", "identical_positions": 34, "similar_positions": 72, "identity": "11.33%" }, { "cls_id": "homologset.agr.RGD:620350", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2X2-1", "uniprot_id": "PSD10_MOUSE", "id": "Q9Z2X2-1", "name": "26S proteasome non-ATPase regulatory subunit 10", "aln": "MEGCVSNIMICNLAYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK---DDAGWSPLHIAASAGRDEIVKALLVK--GAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFY-KASTNIQDTEGNTPLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVAKGGLGLILKRLAESEEASM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z2X3-1", "uniprot_id": "PSD10_RAT", "id": "Q9Z2X3-1", "name": "26S proteasome non-ATPase regulatory subunit 10", "aln": "MEGCVSNLMVCNLAYNGKLDELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNEK---DDAGWSPLHIAASAGRDEIVKALLIK--GAQVNAVNQNGCTALHYAASKNRHEIAVMLLEGGANPDAKNHYDATAMHRAAAKGNLKMVHILLFY-KASTNIQDTEGNTPLHLACDEERVEEAKLLVTQGASIYIENKEEKTPLQVAKGGLGLILKRIAESEEASM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75832-1", "uniprot_id": "PSD10_HUMAN", "id": "O75832-1", "name": "26S proteasome non-ATPase regulatory subunit 10", "aln": "MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK---DDAGWSPLHIAASAGRDEIVKALLGK--GAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY-KASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50086-1", "uniprot_id": "PSD10_YEAST", "id": "P50086-1", "name": "Probable 26S proteasome regulatory subunit p28", "aln": "----MSNYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYD--LVDNKGAKAEDVALNEQVKKFFLNNV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** : : . ..:: :::* : :. ** :.***.* .***: * **..***. ** . **:**:*:***.*.*. *:**:* : ..:* :.::* * ** *..*: .*:: :*:*.**. *:::: .:****: *.**::.:* *::.* **.:* ***. * * : : * :** : .: * ::. :. . .*. :*:: . ", "identical_positions": 71, "similar_positions": 85, "identity": "29.96%" }, { "cls_id": "homologset.agr.RGD:620351", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18265-1", "uniprot_id": "GSK3A_RAT", "id": "P18265-1", "name": "Glycogen synthase kinase-3 alpha", "aln": "-----------MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASV---------------------------GAMGGGVGASSSGGGPSGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPER-------SQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLIIPIIYVKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKS-RTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRSLG-TQLPNNRPLPPLFNFSPGELSIQPSLNAILIPPHLRS-----PSG----------PATLTSS-SQALTETQTGQDWQ-----APDAT-PTLTNSS----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49840-1", "uniprot_id": "GSK3A_HUMAN", "id": "P49840-1", "name": "Glycogen synthase kinase-3 alpha", "aln": "-----------MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASV---------------------------GAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATLGQGPER-------SQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKS-RTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRCLG-TQLPNNRPLPPLFNFSAGELSIQPSLNAILIPPHLRS-----PAG----------TTTLTPS-SQALTETPTSSDWQ-----STDAT-PTLTNSS----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2NL51-1", "uniprot_id": "GSK3A_MOUSE", "id": "Q2NL51-1", "name": "Glycogen synthase kinase-3 alpha", "aln": "-----------MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASV---------------------------GAMGGGVGASSSGGGPSGSGGGGSGGPGAGTSFPPPGVKLGRDSGKVTTVVATVGQGPER-------SQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLITPIIYIKVYMYQLFRSLAYIHSQG-VCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKSSKTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDELRRLG-AQLPNDRPLPPLFNFSPGELSIQPSLNAILIPPHLRS-----PAGPASPL-----TTSYNPS-SQALTEAQTGQDWQ-----PSDATTATLASSS----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18431-2", "uniprot_id": "SGG_DROME", "id": "P18431-2", "name": "Protein kinase shaggy", "aln": "-----------MS------------GRPRTSSFAE-----------------------GNKQSP---------------------------SLVLGGVKTCS------------------------------RDGSKITTVVATPGQGTDR-------VQEVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRELQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIHSLG-ICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPNYTEFKFPQIKSHPWQKVFRI-RTPTEAINLVSLLLEYTPSARITPLKACAHPFFDELRMEGNHTLPNGRDMPPLFNFTEHELSIQPSLVPQLLPKHLQN-----ASGPGGNRPSAGGAASIAASGSTSVSSTGSGASVEGSAQPQSQGTAAAAGSGSGGATAGTGGASAGGPGSGNNSSSGGASGAPSAVAAGGANAAVAGG---AGGGGGAGAATAAATATGAIGATNAGGANVTDS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P83101-1", "uniprot_id": "GSK3H_DROME", "id": "P83101-1", "name": "Putative glycogen synthase kinase-3 homolog", "aln": "------------------------------------------------------------MASQ---------------------------SKNSG-------------------------------------LTNKVTTVVATNAFGADV-------MSEISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQIMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSMGYLHSLG-FCHRDIKPQNMLLDSETGVLKLCDFGSAKQLISGEPNVSYICSRYYRAPELIFGSTDYTTKIDMWSAGCVMSELLLGQLIFPGDSGVDQIVEIVKVMGTPTSEQLHDMNPHYKQFKLPELKPHPWSKVFRI-RTPAEAIDLVSKMLIYSPNARVSPLMGCAHPFFDELRQDPHQQLPNGRSLPPLFNFTDYEKTIEPDTMPLLLPRAQGSSTTKEPSAAHRNRNTAGEESPRKTEDSQKPATAALSKSPGPSGK-ALESPPGFLQHDLGNGDHVAVGTMPMEPLTLEQNHFAAESYAVGEDAEDNLEEDVGDENDYDYDDGGQCNSTYISDDMDEASESDDDDFEEEDEN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50873-1", "uniprot_id": "MRK1_YEAST", "id": "P50873-1", "name": "Serine/threonine-protein kinase MRK1", "aln": "MTDVLRSLVRKISFNNSDNLQLKHKTSIQSNTALEKKKRKPDTIKKVSDVQVHHTVPNFNNSSEYINDIENLIISKLIDGGKEGIAVDHIEHANISDSKTDGKVANKHENISSKLSKEKVEKMINFDYRYIKTKERTIHKRVYKHDRKTDVDRKNHGGTIDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGLQYYFYEKDEE-DEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLHNVPRICHRDIKPQNLLVDPTTFSFKICDFGSAKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGIDQLVEIIKIMGIPTKDEISGMNPNYEDHVFPNIKPITLAEIFKA--EDPDTLDLLTKTLKYHPCERLVPLQCLLSSYFDETKRCDTDTYVKAQNLRIFDFDVETELGHVPLVERPAIEERLKH-----------------------------FVSAPSSSL------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38615-1", "uniprot_id": "RIM11_YEAST", "id": "P38615-1", "name": "Serine/threonine-protein kinase RIM11/MSD1", "aln": "-------------------------MNIQSNNS-----------------------PNLSNN--------------------------------------------------------------------------IVSKQVYYAHPPPTIDPNDP---VQISFPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFFYERDSQ-DEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSRVFKK--EDDQTVEFLADVLKYDPLERFNALQCLCSPYFDELKLDDGKINQITTDLKLLEFDENVELGHLSPDELSSVKKKLY----------------------------------PKSK-------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * . ::::. :*:*:****** : : : : *********:*:*****: *: * * * : * ::*:. ..: **::***:::::*:::*: *::.. : . :: * :**:::: *:* .*********:*:*. * :*:******* * :****************:**: :*:..:*:**:.**::*****: :*.*:**:**:**::*::* *: ::: ***:* :. :*::*. . .:*: ::: : : * * * *. .* .:*** : : : * . : . ", "identical_positions": 120, "similar_positions": 111, "identity": "18.9%" }, { "cls_id": "homologset.agr.RGD:620352", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48962-1", "uniprot_id": "ADT1_MOUSE", "id": "P48962-1", "name": "ADP/ATP translocase 1", "aln": "-------------MGD--QALSFLKDFLAGGIAAAVSKTAVAPIERVKLLLQVQ-HASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KGSSQREFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPD-PKNVHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTLDCWRKIAKDEGANAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05962-1", "uniprot_id": "ADT1_RAT", "id": "Q05962-1", "name": "ADP/ATP translocase 1", "aln": "-------------MGD--QALSFLKDFLAGGIAAAVSKTAVAPIERVKLLLQVQ-HASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KGSSQREFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPD-PKNVHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGRKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12235-1", "uniprot_id": "ADT1_HUMAN", "id": "P12235-1", "name": "ADP/ATP translocase 1", "aln": "-------------MGD--HAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQ-HASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKGMLPD-PKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q26365-1", "uniprot_id": "ADT_DROME", "id": "Q26365-1", "name": "ADP/ATP translocase", "aln": "MGNISASITSQSKMGKDFDAVGFVKDFAAGGISAAVSKTAVAPIERVKLLLQVQ-HISKQISPDKQYKGMVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADTG--KGG-QREFTGLGNCLTKIFKSDGIVGLYRGFGVSVQGIIIYRAAYFGFYDTARGMLPD-PKNTPIYISWAIAQVVTTVAGIVSYPFDTVRRRMMMQSGRKATEVIYKNTLHCWATIAKQEGTGAFFKGAFSNILRGTGGAFVLVLYDEIKKVL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O62526-1", "uniprot_id": "O62526_DROME", "id": "O62526-1", "name": "ADP/ATP translocase", "aln": "MGDEGG----GGGHGKG-DLKSFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQ-EVSKQIAADQRYKGIVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYPLDFARTRLAADVG--KGG-NREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCRDFLPN-PKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNTAHCWLVIAKQEGIGAFFKGALSNIIRGTGGALVLALYDEMKKYF------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18238-1", "uniprot_id": "ADT3_YEAST", "id": "P18238-1", "name": "ADP/ATP translocase 3", "aln": "MSSDAK-----------QQETNFAINFLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKKYSGIVDCFKRTAKQEGLISFWRGNTANVIRYFPTQALNFAFKDKIKLMFGFKKE--EGYGKWFAGNLASGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGSLDGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSG---QAVKYNGAIDCLKKIVASEGVGSLFKGCGANILRSVAGAGVISMYDQLQMILFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P18239-1", "uniprot_id": "ADT2_YEAST", "id": "P18239-1", "name": "ADP/ATP translocase 2", "aln": "MSSNAQVKTPLPPAPAPKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKE--EGYAKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSG---QAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04710-1", "uniprot_id": "ADT1_YEAST", "id": "P04710-1", "name": "ADP/ATP translocase 1", "aln": "MSHTET----------QTQQSHFGVDFLMGGVSAAIAKTGAAPIERVKLLMQNQEEMLKQGSLDTRYKGILDCFKRTATHEGIVSFWRGNTANVLRYFPTQALNFAFKDKIKSLLSYDRER-DGYAKWFAGNLFSGGAAGGLSLLFVYSLDYARTRLAADARGSKSTSQRQFNGLLDVYKKTLKTDGLLGLYRGFVPSVLGIIVYRGLYFGLYDSFKPVLLTGALEGSFVASFLLGWVITMGASTASYPLDTVRRRMMMTSG---QTIKYDGALDCLRKIVQKEGAYSLFKGCGANIFRGVAAAGVISLYDQLQLIMFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :* **::**::**..:******:::* * . ** : : :* *::**. * ...:*. ****** ***:************** * :: : : : ***** ******. ** ***.**:******** * *:* ** : * :*:** ***:** ** **::**. ***.:*: : .: . . : *: :. :* *. ***:********* ** : * .: .* *. ** ::***. :*::*. ..* *: :**::: . ", "identical_positions": 129, "similar_positions": 76, "identity": "39.94%" }, { "cls_id": "homologset.agr.RGD:620353", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51881-1", "uniprot_id": "ADT2_MOUSE", "id": "P51881-1", "name": "ADP/ATP translocase 2", "aln": "---MTDAAVS---------------FAKDFLAGGVAAAISKTAVAPIERVKLLLQVQ-HASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAG--AEREFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPD-PKNTHIFISWMIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGSKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09073-1", "uniprot_id": "ADT2_RAT", "id": "Q09073-1", "name": "ADP/ATP translocase 2", "aln": "---MTDAAVS---------------FAKDFLAGGVAAAISKTAVAPIERVKLLLQVQ-HASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAG--AEREFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPD-PKNTHIFISWMIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05141-1", "uniprot_id": "ADT2_HUMAN", "id": "P05141-1", "name": "ADP/ATP translocase 2", "aln": "---MTDAAVS---------------FAKDFLAGGVAAAISKTAVAPIERVKLLLQVQ-HASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAG--AEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPD-PKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NEI2-1", "uniprot_id": "A0A8M1NEI2_DANRE", "id": "A0A8M1NEI2-1", "name": "ADP/ATP translocase", "aln": "---MSDSVVS---------------FAKDFLAGGVAAAVSETAVAPIERVKLLLQVQ-HASKQITTDKQYKGIVDCVVRIPREQGFLSFWRGNLANVIRYFLTQALNFAFKDKYRRIFLDGVDQRTQFWRYFAGNLAAGGAAGATSLCLVYPLDFARTRLAADVGKTGT-AGREFKGLANCLVKIYRSDGVRGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPD-PENTHIAVSWMIAHTVTIVAGFISYPFDTVRRSMMMQSGLKGADVMYSGSIDCWRKIARNEGPKAFFKGAWSNVLRSLGGSIVLVLYDEFKKVI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q26365-1", "uniprot_id": "ADT_DROME", "id": "Q26365-1", "name": "ADP/ATP translocase", "aln": "MGNISASITSQSKMGKDF---DAVGFVKDFAAGGISAAVSKTAVAPIERVKLLLQVQ-HISKQISPDKQYKGMVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADTGKGG---QREFTGLGNCLTKIFKSDGIVGLYRGFGVSVQGIIIYRAAYFGFYDTARGMLPD-PKNTPIYISWAIAQVVTTVAGIVSYPFDTVRRRMMMQSGRKATEVIYKNTLHCWATIAKQEGTGAFFKGAFSNILRGTGGAFVLVLYDEIKKVL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O62526-1", "uniprot_id": "O62526_DROME", "id": "O62526-1", "name": "ADP/ATP translocase", "aln": "---MGDEGGGGGHGKGD-----LKSFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQ-EVSKQIAADQRYKGIVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGG---NREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCRDFLPN-PKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNTAHCWLVIAKQEGIGAFFKGALSNIIRGTGGALVLALYDEMKKYF------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18238-1", "uniprot_id": "ADT3_YEAST", "id": "P18238-1", "name": "ADP/ATP translocase 3", "aln": "---MSSDAK-----------QQETNFAINFLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKKYSGIVDCFKRTAKQEGLISFWRGNTANVIRYFPTQALNFAFKDKIKLMFGFKKE--EGYGKWFAGNLASGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGSLDGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSG---QAVKYNGAIDCLKKIVASEGVGSLFKGCGANILRSVAGAGVISMYDQLQMILFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P18239-1", "uniprot_id": "ADT2_YEAST", "id": "P18239-1", "name": "ADP/ATP translocase 2", "aln": "---MSSNAQVKTPLPPAPAPKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKE--EGYAKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSG---QAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04710-1", "uniprot_id": "ADT1_YEAST", "id": "P04710-1", "name": "ADP/ATP translocase 1", "aln": "---MSHTET----------QTQQSHFGVDFLMGGVSAAIAKTGAAPIERVKLLMQNQEEMLKQGSLDTRYKGILDCFKRTATHEGIVSFWRGNTANVLRYFPTQALNFAFKDKIKSLLSYDRER-DGYAKWFAGNLFSGGAAGGLSLLFVYSLDYARTRLAADARGSKSTSQRQFNGLLDVYKKTLKTDGLLGLYRGFVPSVLGIIVYRGLYFGLYDSFKPVLLTGALEGSFVASFLLGWVITMGASTASYPLDTVRRRMMMTSG---QTIKYDGALDCLRKIVQKEGAYSLFKGCGANIFRGVAAAGVISLYDQLQLIMFGKKFK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :* **::**:::*..:******:::* * . ** : * :* *::**. * . .:*. ****** ***:*** ********** : :: : : ***** :*****. ** :**.**:******** *:* ** : * ::** ***:** ** **::**. ***::*: : .: . . : *: :. :* *. ***:***** *** ** : * .: .* *. ** ::***. :*::*. ..: *: :**::: ", "identical_positions": 121, "similar_positions": 77, "identity": "37.12%" }, { "cls_id": "homologset.agr.RGD:620354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UKX2-1", "uniprot_id": "MYH2_HUMAN", "id": "Q9UKX2-1", "name": "Myosin-2", "aln": "MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q29RW1-1", "uniprot_id": "MYH4_RAT", "id": "Q29RW1-1", "name": "Myosin-4", "aln": "MSSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKSSVFVVDAKESYVKATVQSREGGKVTAKTEGGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKEEAPSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQVMSNKKPELIEMLLITTNPYDFAYVSQGEITVPSIDDQEELMATDTAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNSVGALAKAMYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNTLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIIGWLDKNKDPLNETVVGLYQKSGLKTLAFLFSGGQAAEAEGGGG--KKGGKKKGSSFQTVSALFRENLNKLMTNLKSTHPHFVRCLIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAVCRGYLMRVEFRKMMERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMATMKEDFEKAKEDLAKSEAKRKELEEKMVALMQEKNDLQLQVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIVKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSEVKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEESKAKNALAHALQSARHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQIDQEKSELQASLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEAIRNLRNTQGMLKDTQLHLDDALRGQDDLKEQLAMVERRANLMQAEIEELRASLEQTERSRRVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELENEVENEQKRNIEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*:********:*****:*******:*****:****.:.***:**.*:*********.*******:***:****.********************************************************:****:**************************************************************:***** .***:*****************************************:*******************.**************: *******************:.:******:*.************:*:****** :***:*************:************************* *****************************:** *:*******:*********:******************************:************************************ ********************************************:****** ****** .********:*:****.***** ***:*****************.:**** ****.*:**.**.** *****************************:*********:*************************************************************************.************************ ******:*********** ***:* ***:::*:****:*******:*:************:*********************:*:* *::****************:*::*************:*************************:*****************************************************************.*.********************************** **************************************** *****:**************:**************:****************************************************************************************:********************************:**********:***********************:*:**********:*:**:.**:*************:*:************************* ************:****************:*******:****:******************************** *********:********************:****:****************:******* ***:*********:***.*****:*************************************:**********::***.****:****************************:******************:*:******************:*:******************** ****:** *****:*****:*******.*:***************:*********:********::***********************************:*******:************************************************* ****************************.***.***** **************************:***********:***:*************.*******:************************************", "identical_positions": 1786, "similar_positions": 130, "identity": "92.01%" }, { "cls_id": "homologset.agr.RGD:620355", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZL2-1", "uniprot_id": "CHST3_RAT", "id": "Q9QZL2-1", "name": "Carbohydrate sulfotransferase 3", "aln": "----------------------------------------------MEKGLALPQDCRDLVHNLKIRGRYVLFLAFVVIVFIFIEKENKIISRVSDKLKQIPQFVADANSTDP-----ALLLSENASLLSLSELDSTFSHLRSRLHNLSLQLGIAPAMEAQGQEAVAEK----PSQQAGAGTRRHVLLMATTRTGSSFVGEFFNQQG-NIFYLFEPLWHIERTVFFQQGGASAAGSALVYRDVLKQLLLCDLYVLEPFISPPPEDHLTQFLFRRGSSRSLCEDPVCTPFVKKVFEKYHCRNRHCGPLNVTLAAEACRRKDHMALKVVRIRQLEFLQPLAEDPRLDLRVIQLVRDPRAVLASRMVAFAGKYESWKKWLS-EGQDQLSENEVQRLRGNCENIRLSAELGLRQPAWLRGRYMLVRYEDVARRPLQKAREMYRSAGIPLTPQVEDWIQKNTQAARDSSDVYSTQKNSSEQFEKWRFSIPFKLAQVVQAVCGPAMHLFGHKLAKDTASLTN--RSISLLEERGTFWVT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88199-1", "uniprot_id": "CHST3_MOUSE", "id": "O88199-1", "name": "Carbohydrate sulfotransferase 3", "aln": "----------------------------------------------MEKGLALPQDFRDLVHSLKIRGRYVLFLAFVVIVFIFIEKENKIISRVSDKLKQIPHFVADANSTDP-----ALLLSENASLLSLSELDSTFSHLRSRLHNLSLQLGVEPAMESQ--EAGAEK----PSQQAGAGTRRHVLLMATTRTGSSFVGEFFNQQG-NIFYLFEPLWHIERTVFFQQRGASAAGSALVYRDVLKQLLLCDLYVLEPFISPPPEDHLTQFLFRRGSSRSLCEDPVCTPFVKKVFEKYHCRNRRCGPLNVTLAGEACRRKDHVALKAVRIRQLEFLQPLVEDPRLDLRVIQLVRDPRAVLASRIVAFAGKYENWKKWLS-EGQDQLSEDEVQRLRGNCESIRLSAELGLRQPAWLRGRYMLVRYEDVARRPLQKAREMYSFAGIPLTPQVEDWIQKNTQATRDSSDVYSTQKNSSEQFEKWRFSMPFKLAQVVQAACGPTMHLFGYKLARDAASLTN--RSISLLEERGTFWVT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7LGC8-1", "uniprot_id": "CHST3_HUMAN", "id": "Q7LGC8-1", "name": "Carbohydrate sulfotransferase 3", "aln": "----------------------------------------------MEKGLTLPQDCRDFVHSLKMRSKYALFLVFVVIVFVFIEKENKIISRVSDKLKQIPQALADANSTDP-----ALILAENASLLSLSELDSAFSQLQSRLRNLSLQLGVEPAMEAAGEEEEEQRKEEEPPRPAVAGPRRHVLLMATTRTGSSFVGEFFNQQG-NIFYLFEPLWHIERTVSFEPGGANAAGSALVYRDVLKQLFLCDLYVLEHFITPLPEDHLTQFMFRRGSSRSLCEDPVCTPFVKKVFEKYHCKNRRCGPLNVTLAAEACRRKEHMALKAVRIRQLEFLQPLAEDPRLDLRVIQLVRDPRAVLASRMVAFAGKYKTWKKWLDDEGQDGLREEEVQRLRGNCESIRLSAELGLRQPAWLRGRYMLVRYEDVARGPLQKAREMYRFAGIPLTPQVEDWIQKNTQAAHDGSGIYSTQKNSSEQFEKWRFSMPFKLAQVVQAACGPAMRLFGYKLARDAAALTN--RSVSLLEERGTFWVT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A5X2-1", "uniprot_id": "B8A5X2_DANRE", "id": "B8A5X2-1", "name": "Sulfotransferase", "aln": "-----------------------------------------------------------------MRNKYAIIIICIV-ALVIIEKENNIISRVSDKLTLRRTQEHPVPYNAS-----NTLVATG---YNSSYLESIYGKNGS-------Q----------------------------AG-RKHILLMATTRTGSSFVGEFFNQQGDNMFYLFEPLWHVERMLSIGSSGTNGSMSVWMYRDVLQHLFLCNFSMLERFISPPPRDHVTPSLFRRESSKALCEEQVCSPVVKYIFERYHCKTRRCGPLNLTMASEACLAKHHRVIKTVRVRQLDTLRSLVEDPRLDVKLIQLVRDPRAILASRMVAFAGKYQNWKSWAV-NGEVPIEDEEVKRLEGNCNNIRISAELGLSQPKWLKKRYMLVRYEDIARYPMQKAAEMYNFTGIPMTTQARDWILKNTHAS-EANGVYSTQKNSSEQVEKWRLSIPFKLAQVVQKVCGPTMKLFGYRFIDSEQTLLN--KSFSVLEEKQFI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMC4-1", "uniprot_id": "Q9VMC4_DROME", "id": "Q9VMC4-1", "name": "Sulfotransferase domain-containing protein", "aln": "--------------------------------------------------MVSLSRTSKLT--VACVGVYTTYVLFIFFLLPMLMPDPVTLQRSLVS------------------------------------------------------------------YSTSHLGDIRNLTLDAGGQPIRSMLVTFRGSGALTLLDNLAHQP-------GCYQHYAPLIAYESRSIAAK-EHHRALDELAALYNCDYNKSAEMIQ------------WGMRSPVFRRFYGAQAKICRSYSQEACWDP-------ETMAAVCKLYPFINMAVYNLRLNLLASLLERKDLN-LNIMLLVRDPRGTIYS---------RMNNKWCS-------DERDCEA-QELCGDMVSDYQMVETLTQAYPQRFSIIRYEDLFLQPDESIKQVFDFYGLPLERNRTRIQKMHPRSGYFFQSSRWKE-LSSQSAFEWISEMMVDDIGAVQDVCGQAMDLWGYRSIQDFNHFSP--ESFQPIMDKAY----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMC3-1", "uniprot_id": "Q9VMC3_DROME", "id": "Q9VMC3-1", "name": "Sulfotransferase domain-containing protein", "aln": "MSTGIGSSSSSTEEQQHLELSADLEACSLLGPQDPSNVDTGRTRAKQRLSLNGKRRRSRMSRRANLIGICGVSSLCILLLIATTQHRPLTTPFNQSAGRDQGASVDGGPSNSLARSAFYDRFQQQLQQQQQSSQTAVYNLTATIVDVLSAQRSRILAEMENFEYPRGGAERLTDMTPETNGTPVRSVVVTSWRSGSTFLGDILNSIP-------GNFYHYEPLLDFGIKQIRDPDDQELAVQNLKNLLNCDYADMIDYLN------------FGKTHTYLFEHNTRLWDVCREFP-RFCWRP-------AFLTRFCRLFPIQSMKTVRLRLAQAEKLLEDQSLSSVRIVLLVRDPRGTMQS---------RRHRVWCG-------GNEDCEDPRLVCQDLRDDYKTAEVLLLKYPSRFRTVRYEDLSLSPSEMTQDILQFYGLPFDPAVEEFLDTHTKVNIGGVSSTYRD-SRS-APFHWMQDLKPEEIKQIQDVCTEAMDLWGYRRIENFNNFSTTQQTFDPMVMPPPFT--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : * : :::: :*: : : : * : . : * * *: : : . : : * * : . .:* * . :.:: ******. : * . . * : : : . * .: . : *: :****: * : :: *:*: :.: . : * .* .: . :* .* :* *:*:: . : .:.. : ", "identical_positions": 34, "similar_positions": 74, "identity": "6.38%" }, { "cls_id": "homologset.agr.RGD:620356", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13542-1", "uniprot_id": "MYH8_MOUSE", "id": "P13542-1", "name": "Myosin-8", "aln": "MSAGSDAEMAIFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSVIQSKDGGKVTVKTESGATLTVKEDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKEESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFSPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQCLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPTKGKAEAHFSLVHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYASAEADGGAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGYLMRVEYQKMLLRRESIFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVEMNKKRETEFQKLRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLSSNAEAIAKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINELTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKVLSEWRQKYEETQAELESCQKESRTLSTELFKVKNAYEESLDHLETLRRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHVRVVETMQS-TLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13535-1", "uniprot_id": "MYH8_HUMAN", "id": "P13535-1", "name": "Myosin-8", "aln": "MSASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVTVKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQS-TLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04462-1", "uniprot_id": "MYH8_RAT", "id": "P04462-1", "name": "Myosin-8", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RAA--LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNASLINAKKKLENDVSQLQSEVEEVIQRARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35415-1", "uniprot_id": "MYSP1_DROME", "id": "P35415-1", "name": "Paramyosin, long form", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSQAVR--------------------------SSKYSYRATSTGPGTADVNIEYIQDLSSLSRLEDKIRLLQDDLEVERELRQRIEREKADLSVQVIQMSERLEEAEGGAEHQFEANRKRDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKDKAKFQTEVYELLSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQENIELTKDVQDLKVQLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEESEARIDLERQLVKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLEKMKTRLASEVEVLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADLVRTVHELDKVKDNNNQLTRENKKLGDDLHEAKGAINELNRRLHELELELRRLENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKKKLQIQITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATLDQYAVAQRRLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVELNAVAGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHRTFVTTSTVPGSQVYIQETTRTITE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:.*:**: : *:.::*::: .* : :*:.*:: * * *.**:. *.***:::* : *: *** :. * ::*: :*. .: :.*::::**: .:** :**.:* **:*. **:*.* *: *.*: *.*****:*:** *:*:*::*:**::* ***:** ***: * ***:**:: *** :** **:: *:** .* * *: . ::.*::*:*** **:*** ***.:* :*.* * . *. :. ", "identical_positions": 106, "similar_positions": 93, "identity": "5.43%" }, { "cls_id": "homologset.agr.RGD:620357", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61508-1", "uniprot_id": "ECM1_MOUSE", "id": "Q61508-1", "name": "Extracellular matrix protein 1", "aln": "MGTVSRAALILACLALASAASEGAFKASDQREMTPERLFQHLHEVGYAAPPSPPQTRRLRVDHSVTSLHDPPLFEEQREVQPPSSPEDIPVYEEDWPTFLNPNVDKAGPAVPQEAIPLQKEQPPPQVHIEQKEIDPPAQPQEEIVQ---KEVKPHTLAGQLPPEPRTWNPARHCQQGR-RGVWGHRLDGFPPGRPSPDNLKQICLPERQHVIYGPWNLPQTGYSHLSRQGETLNVLETGYSRCCRCRSDTNRLDCLKLVWEDAMTQFCEAEFSVKTRPHLCCRLRGEERFSCFQKEAPRPDYLLRPCPVHQNGMSSGPQLPFPPGLPTPDNVKNICLLRRFRAVPRNLPATDAIQRQLQALTRLETEFQRCCRQGHNHTCTWKAWEGTLDGYCERELAIKTHPHSCCHYPPSPARDECFAHLAPYPNYDRDILTLDLSRVTPNLMGQLCGSGRVLSKHKQIPGLIQNMTIRCCELPYPEQACCGEEEKLAFIENLCGPRRNSWKDPALCCDLSPEDKQINCFNTNYLRNVALVAGDTGNATGLGEQGPTRGTDANPAPGSKEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62894-1", "uniprot_id": "ECM1_RAT", "id": "Q62894-1", "name": "Extracellular matrix protein 1", "aln": "MGTIRSSALILACLALASAASEGAFKVSDQREMKPEHLFQHLHEVGYAAPPSPPQTRRLQVHHSETSPHDPPLFEEQKEVQPPSSPEDIPVYEEEWLTFLNPNVGKVDPALPQEAIPLQKEQPPPRIPIEQKEIDPPVQHQEEIVQSRQKEEKPPTLTGQHPPEPRTWNPARHCQQGR-RGIWGHRLDGFPPGRPSPDNLKQICLPERQHVVYGPWNLPQTGYSHLSRQGEALNLLETGYSRCCRCRSDTNRLDCVKLVWEDAMTQFCEAEFSVKTRPHLCCKQRGEERFSCFQKEAPRPDYLLRPCPIHQTGISSGTQLPFPPGLPTPDNVKNICLLRRFRSVPRNLPATDAIQRQLQALTRLETEFQRCCRQGHNHTCTWKAWEDTLDGYCDRELAIKTHPHSCCHYPPSPARDECFAHLAPYPNYDRDLLTVDLSRVTPNLMDHLCGNGRVLSKHKQIPGLIQNMTVRCCELPYPEQACCGEEEKLAFIEDLCGPRRNSWKDPALCCTLSPGDKQANCFNTNYLRNVALVAGDTGNATGLGQQGPTGGTNVGPAPGSKEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16610-1", "uniprot_id": "ECM1_HUMAN", "id": "Q16610-1", "name": "Extracellular matrix protein 1", "aln": "MGTTARAALVLTYLAVASAASEGGFTATGQRQLRPE----HFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPP-FEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQK------------------EGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQICLPNRQHVVYGPWNLPQSSYSHLTRQGETLNFLEIGYSRCCHCRSHTNRLECAKLVWEEAMSRFCEAEFSVKTRPHWCCTRQGEARFSCFQEEAPQPHYQLRACPSHQPDISSGLELPFPPGVPTLDNIKNICHLRRFRSVPRNLPATDPLQRELLALIQLEREFQRCCRQGNNHTCTWKAWEDTLDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNYDRDILTIDIGRVTPNLMGHLCGNQRVLTKHKHIPGLIHNMTARCCDLPFPEQACCAEEEKLTFINDLCGPRRNIWRDPALCCYLSPGDEQVNCFNINYLRNVALVSGDTENAKGQGEQGSTGGTNISSTSEPKEE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :**:*: **:*******.*..:.**:: ** *::*********** :* * :.*. :* *.** ** * :****.* * *: :*. . * :..*.:****:***** *. : *** * .* .: .* ***.:**.*:****.* :* ******************:*****:****:********:.****:****:**.** ******:***.****:* *****:**::************* ** :** ******:***:*.* **.** ** .:*** :******:** **:**** *****:*********.:**:* ** :** *********:**********.*** **:** *:*** * **::****:******: *********:**:*:.*******.:***. ***:***:*****:*** ***:**:******.*****:**::******* *:****** *** *:* **** *********:*** **.* *:**.* **: ..:. .***", "identical_positions": 364, "similar_positions": 108, "identity": "64.65%" }, { "cls_id": "homologset.agr.RGD:620358", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q10472-1", "uniprot_id": "GALT1_HUMAN", "id": "Q10472-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 1", "aln": "---------MR---KFAYCKVVLATSLIWVLLDMFLLLYFSECN-----KCDEKKE----------------------------------------RGLPAGDV--------------LEPVQKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCNGSRSQQWLLRNVTLPEIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q10473-1", "uniprot_id": "GALT1_RAT", "id": "Q10473-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 1", "aln": "---------MR---KFAYCKVVLATSLVWVLLDMFLLLYFSECN-----KCEEKKE----------------------------------------RGLPAGDV--------------LELVQKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIAFNRSLPDVRLEGCKTKVYPDSLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCTGSRSQQWLLRNVTLPEIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08912-1", "uniprot_id": "GALT1_MOUSE", "id": "O08912-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 1", "aln": "---------MR---KFAYCKVVLATSLVWVLLDMFLLLYFSECN-----KCEEKQE----------------------------------------RGLPAGDV--------------LELVQKPHEGPGEMGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSRGQVITFLDAHCECTAGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRLGLRRKLQCKPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCTGSRSQQWLLRNVTLPEIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FDA0-1", "uniprot_id": "E7FDA0_DANRE", "id": "E7FDA0-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "---------MR---KFAYCKVVLATSLVWVMLDMFILLYFSECN-----KCDDKKE----------------------------------------RGLPGRD----------------TVVQRPHDGPGEMGKPVVIAKDQQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVIDRSPRHLLEEIVLVDDASERDFLKRQLEHYVRKLEVPVRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTTGWLEPLLSRIKLDKKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISTRTSLRQRLQCKPFSWYLENVYPDSQIPRHYYSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVMMLKCHHLKGNQLWEYDPVKLSLVHVNSNQCLDKASEDDSQVPSVRDCSGARSQQWLLRNVTLPEIF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6WV17-1", "uniprot_id": "GALT5_DROME", "id": "Q6WV17-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 5", "aln": "MTFSTFTRKMRGRMRSNTCRIVLLTSLVWVIFDFVLIARYSDCIGKDGWRCKRSGEYDVELPNAERLVDDNQLVDDNEINTEKSLDGESGGALIMGQGFASGGISMTYPSVVLKKWFLAPSVQEAKGKPGEMGKPVKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGFNWKLNFRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLEMSFRIWQCGGILEIIPCSHVGHVFRDKSPYTFPGGVAKIVLHNAARVAEVWLDEWRDFYYSMSTGARKASAGDVSDRKALRDRLKCKSFRWYLENVYPESLMPLDYYYLGEIRNAETETCLDTMGRKYNEKVGISYCHGLGGNQVFAYTKRQQIMSDDLCLDASSSNGPVNMVRCHNMGGNQEWVYDAEEKWIRHTNTGQCLQRATRDDANTPLLRPCSYGKGQQWLMESKFKWQAH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : *::** ***:**::*:.:: :*:* :*. . * :*:.. . **..: ******** *. : :: *** ** *****:**:**::****.*** ***: * *...** **:*********:****** ***:**** :::**:*********** : ** ** ** * . *:* *:********* ** *:************ *******:** :::************:****::.** *:************ **.*** **:.*** *:*************:*** ***:** ***********:********* ***:.*********. :*******..:*: :* *:****:**:::*:* :*.*. *.. **:* * .** :*:**.* *****:**:* :* .*: ******.**: ***.*.** ****** ***:******:** .::* :******.*. **** *::**:: *** * **. : : *.*:.***::*:.:*::.* :* *. .:.****:.. : .", "identical_positions": 337, "similar_positions": 134, "identity": "53.49%" }, { "cls_id": "homologset.agr.RGD:620359", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28492-1", "uniprot_id": "GLSL_RAT", "id": "P28492-1", "name": "Glutaminase liver isoform, mitochondrial", "aln": "MRSMRALQNALSRAGSHGQRGGWGHPSRGPLLGGGVRYYFGEAAAQGRGTPHSHQPQHSDHD-ASNSGMLPRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLQDCMSKMQRMVQESSSGGLLDRELFQKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDAKELTGGKVAAYIPHLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISVSTLGTDYVHKFVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEFMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSHRGISFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTVVNLLFAAYSGDVSALRRFALSAVDMEQKDYDSRTALHVAAAEGHIDVVKFLIEACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYHDSY-----------MLSETQAEVAAETLSKENLESMV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q571F8-1", "uniprot_id": "GLSL_MOUSE", "id": "Q571F8-1", "name": "Glutaminase liver isoform, mitochondrial", "aln": "MRSMRALQNALSRAGSHGRRGGWGHPSRGPLLGRGVRYYLGEAAAQGRGTPHSHQPQHSDHD-ASHSGMLPRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLQDCMSKMQRMVQESSSGGLLDRELFQKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDAKEPTGGKVAAYIPHLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISVSTLGTDYVHKFVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEFMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSQRGINFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYHDSY-----------LLSETQAEAAAETLSKENLESMV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI32-1", "uniprot_id": "GLSL_HUMAN", "id": "Q9UI32-1", "name": "Glutaminase liver isoform, mitochondrial", "aln": "MRSMKALQKALSRAGSHCGRGGWGHPSRSPLLGGGVRHHLSEAAAQGRETPHSHQPQHQDHD-SSESGMLSRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLRDCMSEMHRVVQESSSGGLLDRDLFRKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDVKELTGGKVAAYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHKFVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEYMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSHRGTSFCQKLVSLFNFHNYDNLRHCARKLDPRREGAEIRNKTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRWGNIPLDDAVQFNHLEVVKLLQDYQDSY-----------TLSETQAEAAAEALSKENLESMV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZE4-1", "uniprot_id": "A0A8M9PZE4_DANRE", "id": "A0A8M9PZE4-1", "name": "glutaminase", "aln": "MHCVKTLRATRAGVLLIRNAGKWERVAGSLGRKHSPVRPLHTSASPGQHPRQQHAVNETDAATYSREKVVSGLEDLLFYTITQGEEKISVARFLTALKSTGLQTSDPRLRDCMRQIHHAVQDSVGTAMMDQELFRKCVGSNIVLLTQAFQRKFIIPDFEAFTSLINHLYCDAQTQQGGKVANYIPQLAKFSPDLWGVSLCTVDGQRHAVGDTNVPFCLQSCVKPLEYALAVHETGSEHVHRYVGKEPSGLKFNKLSLDEEEKPHNPMVNAGAIVISSLLKPGYNKAEKFDYMVDYLKRMAGREYVGFSNATFQSEKETGYRNYAIGYYLKEKKCFPNGADMTAALDFYFQLCSIEVTCESGSVMAATLANGGICPITGERVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVSGAVLLVVPNIMGVMCWSPALDRVGNSIRGIHFCQELVSLFNFHNYDNLRHFAKKLDPRRQTGHERNKSVVDLMFAAYSGDVSALRRIALSAVNMELTDYDSRTALHVASAEGHLEAVKFLTDTCKVNPYVKDRWGNTPLDDAMQFGHNTVAKVLQEYQSIYTHTLLPEVLSADTCPDSSIDADELKSMETLESLI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB40E7Z6-1", "uniprot_id": "A0AB40E7Z6_DANRE", "id": "A0AB40E7Z6-1", "name": "glutaminase", "aln": "MFSLRTLRLPNIGLIGLLSKDAVKSSVRSPNVVRGPLSLFSRVNVISKFTEAASADQPKSKANMTNKDLFSGLEDMLFYTITEGAEKVPVSHFTAALKSTGLLTSDPRLRDCMEKIRRAVRDSTGEVMMDRELFKKCASGNIVLLSLAFRRKFIIPEFEAFVDIINHIYYTSKLQQDGQVAKYIPHLTKFSPDLWGVSLCTVDGQRHSVGDTKVPFCLQSCVKPLEYAIAVHEHGTEHVHQYVGKEPSGFKFNKLSLDEEDKPHNPMVNAGAIVISSLIK-GVNKAEKFDYVMDFVKKMTGSEYVGFSNATFQSEKETGDRNYAIGYYLKEKKCFPDGVEMIDALDFYFQLCAIEVTCESGSVMAATLANGGICPITGERVLSTEAVRNTLSLMHSCGMYDYSGQFAFHVGLPAKSGVSGAVLLVVPNVMGVMCWSPPVDKVGNSVRGIRFCQELVSLFNFHNYDNLRHFLKKQDPRRQSGDDRNKSVVNLMFAAHSGDVSALRRFALSSMNMELRDYDSRTPLHVAAAEGHVDVVLFLIQACKVNPFVKDRWGNIPRDDAMQFGQKDVVKILEEYEQTY---------SPQTSQTDTEDLSQPSKCSSLGCNLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .:::*: . . . . : .: . : . :.. :.. * *:*****::* *::.: :* :***:*** ******:*** :::: *::* . ::*::**:**...*****: **::**:**:** *.. ::::: : .*:** ***:*:* .****************:**.*::*********** **::: *:::**::*******:::*****:** ************:***:* . *******::::::::*:* *::************** ****************.*.:* ***:*****::************************* ***:*****************:**************.****:******:**:** **.:*::*** ** ***:*************** :* ****: .. ***:**:*:***:*********:***:::** ******.****:****::.* ** ::*****:.****** * ***:**.: *.*:*::*.. * . .: : . ..* . : ", "identical_positions": 338, "similar_positions": 151, "identity": "54.96%" }, { "cls_id": "homologset.agr.RGD:62036", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24483-1", "uniprot_id": "ADX_RAT", "id": "P24483-1", "name": "Adrenodoxin, mitochondrial", "aln": "MAAAPGARLLRAACASVAFRGLDCRRLLVCGTRAGPAVPQWTPSPHTLAEAGPGRPLSVSARAR-SSSEDKVTVHFKNRDGETLTTKGKVGDSLLDVVIENNLDIDGFGACEGTLACSTCHLIFEDHIYEKL-DAITDEENDMLDLAFGLTNRSRLGCQVCLTKAMDNMTVRVPEAVADVRQSVDMSKNS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P46656-1", "uniprot_id": "ADX_MOUSE", "id": "P46656-1", "name": "Adrenodoxin, mitochondrial", "aln": "MAAAPGARLLRAACASVPFRGLDRCRLLVCGTGAGTAISPWTPSPRLHAEAGPGRPLSVSARAR-SSSEDKITVHFKNRDGETLTTKGKIGDSLLDVVIENNLDIDGFGACEGTLACSTCHLIFEDHIYEKL-DAITDEENDMLDLAFGLTDRSRLGCQVCLTKAMDNMTVRVPEAVADVRQSVDMSKNS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10109-1", "uniprot_id": "ADX_HUMAN", "id": "P10109-1", "name": "Adrenodoxin, mitochondrial", "aln": "MAAAGGARLLRAASAVLG--GPAGRWLHHAGSRAGSSGLLRNRGPGGSAEAS--RSLSVSARAR-SSSEDKITVHFINRDGETLTTKGKVGDSLLDVVVENNLDIDGFGACEGTLACSTCHLIFEDHIYEKL-DAITDEENDMLDLAYGLTDRSRLGCQICLTKSMDNMTVRVPETVADARQSIDVGKTS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8SZA8-1", "uniprot_id": "ADXH2_DROME", "id": "Q8SZA8-1", "name": "Adrenodoxin-like protein 2, mitochondrial", "aln": "-------------------------MLVINSCRAASRLALRSLNLRSPIATR-----TFSTGLA-LKTKDVVNITFVRANGDKIKTSGKVGDSLLDVVVNNNVDLDGFGACEGTLTCSTCHLIFKTSDFEKLPDKPGDEELDMLDLAYELTDTSRLGCQITLSKDMEGLEVHVPSTINDARAA------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E7F7J1-1", "uniprot_id": "E7F7J1_DANRE", "id": "E7F7J1-1", "name": "", "aln": "MSACVLRAFL--------------QRAAVMRQAAQQTISQTRAFPQSYTHIR-----GINTYANSLRAEEKVTVHFLNRDGKRITVKASIGESLLDVVVDRDLDIDGFGACEGTLACSTCHLIFEEDVYKKL-GPVSDEEMDMLDLAYGLTDTSRLGCQVCLRKDLDGMILRVPDVISDARADSEKESSTAPPKI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ..: ::: :.: * . :*. :.....:*:******::.::*:**********:********: ::** . *** ******: **: ******: * * ::.: ::**..: *.* ", "identical_positions": 54, "similar_positions": 44, "identity": "27.69%" }, { "cls_id": "homologset.agr.RGD:620360", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54968-1", "uniprot_id": "NF2L2_RAT", "id": "O54968-1", "name": "Nuclear factor erythroid 2-related factor 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMDLELPPPGLQSQ--------------------------------------------------------------------------------------------------------------------------------------------------QDMDLIDILWRQDIDLGVSREVFDFSQRQKD----------------------------------------------YELEKQKKLEKERQE-------QLQKEQEKAFFAQLQLDEETGEFLPIQPAQHIQTDTSG-------SVSYSQVAHIPKQDALYFEDCMQLLA----------------------------------ETFPFVDDHEVSSPT----------------------FQSLALDIPSHVESSVFTTPDQAQSLDSS-LETAMTDLSSIQQDMEQV--------------------------------------WQELFSIPELQCLNTENKQQAETTTVPSPEATLTEMDSNYHFYSSIPSLEKEVDSCS-----------------------------------------------PHFLHGFEDSFSSILSTDDASQLN--SLDSNPTLNTDFGDEFYSAFLAEPSGGG------------------------------------SMPSSAAISQS---------------------------------------LSELLG-------GPIEGCDLSLCKAFNQKHTEGTVEFNDSDSGISLN------------------------TSPSRASPEHSVESSIYGD------------------------------------PPPGFSDSEMEELDSAPGSVKQNGPKAQPTHSSGD--------TVQPLSPAQGHSAAVHESQCENTTKKEVPVSPGHQKVPFTKDKHSSR-----------------LEAHLTRDELRAKALHIPFPVEKIINLPVDDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLGHLKDEREKLLREKGENDRNLHLLKRKLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDTKKN--------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60795-1", "uniprot_id": "NF2L2_MOUSE", "id": "Q60795-1", "name": "Nuclear factor erythroid 2-related factor 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMDLELPPPGLQSQ--------------------------------------------------------------------------------------------------------------------------------------------------QDMDLIDILWRQDIDLGVSREVFDFSQRQKD----------------------------------------------YELEKQKKLEKERQE-------QLQKEQEKAFFAQFQLDEETGEFLPIQPAQHIQTDTSG-------SASYSQVAHIPKQDALYFEDCMQLLA----------------------------------ETFPFVDDHES-----------------------------LALDIPSHAESSVFTAPHQAQSLNSS-LEAAMTDLSSIEQDMEQV--------------------------------------WQELFSIPELQCLNTENKQLADTTAVPSPEATLTEMDSNYHFYSSISSLEKEVGNCG-----------------------------------------------PHFLHGFEDSFSSILSTDDASQLT--SLDSNPTLNTDFGDEFYSAFIAEPSDGG------------------------------------SMPSSAAISQS---------------------------------------LSELLD-------GTIEGCDLSLCKAFNPKHAEGTMEFNDSDSGISLN------------------------TSPSRASPEHSVESSIYGD------------------------------------PPPGFSDSEMEELDSAPGSVKQNGPKAQPAHSPGD--------TVQPLSPAQGHSAPMRESQCENTTKKEVPVSPGHQKAPFTKDKHSSR-----------------LEAHLTRDELRAKALHIPFPVEKIINLPVDDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLGHLKDEREKLLREKGENDRNLHLLKRRLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDTKKN--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16236-1", "uniprot_id": "NF2L2_HUMAN", "id": "Q16236-1", "name": "Nuclear factor erythroid 2-related factor 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMDLELPPPGLPSQ--------------------------------------------------------------------------------------------------------------------------------------------------QDMDLIDILWRQDIDLGVSREVFDFSQRRKE----------------------------------------------YELEKQKKLEKERQE-------QLQKEQEKAFFAQLQLDEETGEFLPIQPAQHIQSETSG-------SANYSQVAHIPKSDALYFDDCMQLLA----------------------------------QTFPFVDDNEVSSAT----------------------FQSLVPDIPGHIESPVFIATNQAQSPETSVAQVAPVDLDGMQQDIEQV--------------------------------------WEELLSIPELQCLNIENDKLVETTMVPSPEAKLTEVD-NYHFYSSIPSMEKEVGNCS-----------------------------------------------PHFLNAFEDSFSSILSTEDPNQLTVNSLNSDATVNTDFGDEFYSAFIAEPSISN------------------------------------SMPSPATLSHS---------------------------------------LSELLN-------GPIDVSDLSLCKAFNQNHPESTAEFNDSDSGISLN------------------------TSPSVASPEHSVESSSYGD------------------------------------TLLGLSDSEVEELDSAPGSVKQNGPK-TPVHSSGD--------MVQPLSPSQGQSTHVHDAQCENTPEKELPVSPGHRKTPFTKDKHSSR-----------------LEAHLTRDELRAKALHIPFPVEKIINLPVVDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGENDKSLHLLKKQLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDVKKN--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20482-1", "uniprot_id": "CNC_DROME", "id": "P20482-1", "name": "Segmentation protein cap'n'collar", "aln": "MISNKKSYAMKMLQLALALSLLHYNPDYLLHRWDSQLELGTHGDGWELEMLRTVHRLDMDHNPYGNRKGLSPRIEDLLNFDDPSLGGMANGIGGCKLPPRFNGSTFVMNLHNTTGNSSVQTAALQDVQSTSAAATGGTMVVGTGGAPTSGGQTSGSALGEIHIDTASLDPGNANHSPLHPTSELDTFLTPHALQDQRSIWEQNLADLYDYNDLSLQTSPYANLPLKDGQPQPSNSSHLDLSLAALLHGFTGGSGAPLSTAALNDSTPHPRNLGSVTNNSAGRSDDGEESLYLGRLFGEDEDEDYEGELIGGVANACEVEGLTTDEPFGSNCFANEVEIGDDEEESEIAEVLYKQDVDLGFSLDQEAIINASYASGNSAATNVKSKPEDETKSSDPSISESSGFKDTDVNAENEASAASVDDIEKLKALEELQQDKDKNNENQLEDITNEWNGIPFTIDNETGEYIRLPLDELLNDVLKLSEFPLQDDLSNDPVASTSQAAAAFNENQAQRIVSETGEDLLSGEGISSKQNRNEAKNKDNDPEKADGDSFSVSDFEELQNSVGSPLFDLDEDAKKELDEMLQSAVPSYHHPHPHHGHPHAHPHSHHHASMHHAHAHHAAAAAAAHQRAVQQANYGGGVGVGVGVGVGVGSGTGSAFQRQPAAGGFHHGHHQGRMPRLNRSVSMERLQDFATYFSPIPSMVGGVSDMSPYPHHYPGYSYQASPSNGAPGTPGQHGQYGSGANATLQPPPPPPPPHHAAMLHHPNAALGDICPTGQPHYGHNLGSAVTSSMHLTNSSHEADGAAAAAAAYKVEHDLMYYGNTSSDINQTDGFINSIFTDEDLHLMDMNESFCRMVDNSTSNNSSVLGLPSSGHVSNGSGSSAQLGAGNPHGNQANGASGGVGSMSGSAVGAGATGMTADLLASGGAGAQGGADRLDASSDSAVSSMGSERVPSLSDGEWGEGSDSAQDYHQGKYGGPYDFSYNNNSRLSTATRQPPVAQKKHQLYGKRDPHKQTPSALPPTAPPAAATAVQSQSIKYEYDAGYASSGMASGGISEPGAMGPALSKDYHHHQPYGMGASGSAFSGDYTVRPSPRTSQDLVQLNHTYSLPQGSGSLPRPQARDKKPLVATKTASKGASAGNSSSVGGNSSNLEEEHLTRDEKRARSLNIPISVPDIINLPMDEFNERLSKYDLSENQLSLIRDIRRRGKNKVAAQNCRKRKLDQILTLEDEVNAVVKRKTQLNQDRDHLESERKRISNKFAMLHRHVFQYLRDPEGNPCSPADYSLQQAADGSVYLLPREKSEGNNTATAASNAVSSASGGSLNGHVPTQAPMHSHQSHGMQAQHVVGGMSQQQQQQSRLPPHLQQQHHLQSQQQQPGGQQQQQHRKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *.* .* .* :: :: ::*::**:***.* : : : ::** * **: :*: **:. :: : :*:****:: : : :: . . . . ** .: * : :: * :. ::*.. * .* * * .. .. ..: * . : . * . . :: ::*. .: : . .:: :. . : :** . ::::. *.*.. . . ... **: : : .:.:* : :..: : : .: :.:.. :*. :: . . .:**.. :*:. ::** * : * * .*.. .* . .:.*.: * . : ::.: .* . : . **. . *::.. :.* .: ::.:: : * .. *:* . :. . . :..: . . .:* . .: * *:. * :*: * ****** **::*:**:.* .*****: :*** :** ::.* **:***********************::*: **:::. : ..: :* :::.. : . : :..::: *: .**. *** :*:* **::*****: **.*:*:*:.*. . :. ", "identical_positions": 144, "similar_positions": 246, "identity": "10.41%" }, { "cls_id": "homologset.agr.RGD:620361", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88422-1", "uniprot_id": "GALT5_RAT", "id": "O88422-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 5", "aln": "MNKIRKFFRGSGRVLAFIFVASVIWLLFDMAALRLSFSEINTGILKEDIMRREQTGFRVEADQMTILSPSSRGMRPPRN----GAGGKESFRKAENRVLKVEENVDQVQRKGKMQFLLGRGKAVSLWHRTHVQTLPVTLPMQKTQGRDSKPEVSSLHMMSKQTTVLGSEKDSFTVSRGVPLNKTAEHTETLDKKQEAPENYNLSSDTSKQASQRALNVTISVRTDRSKQQSQTVTKSSIQFASLPILKPEEVTVTKKTEAQGKDL---KYEAHKARPLLKFTADVGHLKKQSTNETGLGVLPEADGAKVAPGKKLNFSESQIVIITKEEGQKTDTKEVPNSKIQTVFPKLLGESQGKHIPRSQSQTLSSPLAPKRA-VSQSKPTLAEELHTARSNLTAKATTVGHQQSHAN--ISENPGKHHVLRIDVTLSPRDLNAPGQFGRPVVVPPGKKKEAEQRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNDLPTTSIIMCFVDEVWSALLRSVHSVLNRSPPHLIKEILLVDDFSTKDYLKANLDKYMSQFPKVRILRLKERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLNRKKVACPVIEVINDKDMSYMTVDNFQRGVFTWPMNFGWRTIPPDVIAKNGIKETDIIRCPVMAGGLFSIDKSYFYELGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVERNLVRVAEVWLDEYKELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCQSFKWYLDNVFPDLKAPVVRASGVFINLALGKCVSIKNITVVLEDCDGSSELQQFNYTWVRLIKHGEWCVAPIPDKGSLTLYPCDNRNNRLKWLHRSASAFHPELVDHIVFESYQQLLCMEGNFSQKTLKLAACNPTEPQQKWKFEKYYDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C102-1", "uniprot_id": "GALT5_MOUSE", "id": "Q8C102-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 5", "aln": "MNKIRKFFRGSGRVLAFIFAASVIWLLFDMAALRLSFSEINAGLLKEDIIRREHTGFRVEPDQVKVLYTSIRGMGLPRN----GAWGKENFRKAENHELKVEENMDQVQRKGKMQNLLGRRKAVPLWHLAHLQTLPVTIPMQKTQGRDSKPEVSSQYMMSKWMTVLESEKTPFTASRGVPLTKIAGRTETFDKKQEAPQNYNVSSDTSKQASERTLNMTISVKTDRSKQKSQTVTKLRMHFASPPILKSEEVTVIKKAEAQSKDL---KHEALKALPLLKFIADMGHLKNQSTNETQLGRLPEDDAAKVAPGKKLNFSESHVVIITKEEELKTDTKEVPNSKTQTVFPKLLGGSPHKQIPRNQSKTSSSPPALKKA-VSQSKPTISGGLHTARSNLTAKAPTVGYQQSHAN--IPENPGMHHVFRIDVTLSPRDLNAPGQFGRPVVVPPEKKKEAEQRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNDLPTTSIIMCFVDEVWSALLRSVHSVLNRSPPHLIKEILLVDDFSTKEYLKADLDKYMSQFPKVRILRLKERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLNRKKVACPVIEVINDKDMSYMTVDNFQRGVFTWPMNFGWKTIPPDVVAKNGIKETDIIRCPVMAGGLFSIDKSYFYELGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVERNLVRVAEVWLDDYRELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLDNVFPDLKAPVVRASGVLINMALGKCVSIENITVTLEDCDGSSQLQQFNYTWVRLIKHGEWCVAPIPEKGSLTLYHCDNRNNRLKWLHKSASAFHPELVDHIVFENYQQLLCMEGNFSQKTLKLAACNPMELQQKWKFEKYYEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7M9-1", "uniprot_id": "GALT5_HUMAN", "id": "Q7Z7M9-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 5", "aln": "MNRIRKFFRGSGRVLAFIFVASVIWLLFDMAALRLSFSEINTRVIKEDIVRRERIGFRVQPDQGKIFYSSIKEMKPPLRGHGKGAWGKENVRKTEESVLKVEVDLDQTQRERKMQNALGRGKVVPLWHPAHLQTLPVTPNKQKTDGRGTKPEASSHQGTPKQTTAQGAPKTSFIAAKGTQVVKISVHMGRVSLKQEPRKSHSPSSDTSKLAAERDLNVTISLSTDRPKQRSQAVANERAHPASTAVPKSGEAMALNKTKTQSKEVNANKHKANTSLPFPKFTVNSNRLRKQSINETPLGSLSKDDGARGAHGKKLNFSESHLVIITKEEEQKADPKEVSNSKTKTIFPKVLGKSQSKHISRNRSEMSSSSLAPHRVPLSQTNHALTGGLEPAKINITAKAPSTEYNQSHIKALLPEDSGTHQVLRIDVTLSPRDPKAPGQFGRPVVVPHGKEKEAERRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNNLPTTSVIMCFVDEVWSTLLRSVHSVINRSPPHLIKEILLVDDFSTKDYLKDNLDKYMSQFPKVRILRLKERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLSRKKVACPVIEVINDKDMSYMTVDNFQRGIFVWPMNFGWRTIPPDVIAKNRIKETDTIRCPVMAGGLFSIDKSYFFELGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVERNLVRVAEVWLDEYKELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLENVFPDLRAPIVRASGVLINVALGKCISIENTTVILEDCDGSKELQQFNYTWLRLIKCGEWCIAPIPDKGAVRLHPCDNRNKGLKWLHKSTSVFHPELVNHIVFENNQQLLCLEGNFSQKILKVAACDPVKPYQKWKFEKYYEA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:****************.*********************: ::****:***: ****:.** .:: .* : * * . ** ***..**:*: **** ::**.**: *** *** *.*.*** :*:****** ***:**.:***.** .* *. : * .* .::*. : * : : .. ***. :.:. ****** *::* **:***: ***.**:**:*:: : ** .: *. *. . :*:::*.*:: *::* .: *: ** .: .:*::** *** ** *.: *.*: * *********::******* *:*.***.*** :*:***:** * *:*.*.:*: **. * ::. :**:: ::: *..*: *:****.:. ::*** : :.*:.* *:*:********** :************ *:****:************************************:*****:**********:********:********************:*** :*************************************************************.****************************:*.*******:******:*** ***** ******************:***********************************************************************:*:********************************:******:******:**:******:**:*****:**:* ** *******.:********:**** ****:****:**:: *: *****: *****:*:*.******:*****. *****:******* **:***:* : *********:.", "identical_positions": 661, "similar_positions": 170, "identity": "70.32%" }, { "cls_id": "homologset.agr.RGD:620362", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0C5-1", "uniprot_id": "GALT7_RAT", "id": "Q9R0C5-1", "name": "N-acetylgalactosaminyltransferase 7", "aln": "MRLKIGFILRSLLVVGSFLGLVVLWSSLSSRPDDPSPLSRMREDRDVNNPLPNRGGNGLAPGDDRFKPVVPWPHVEGVEVDLESIRRKNKAKNEQERHAGGDSQKDIMQRQYLTFKPQTFTYRDPVLRPGVLGNFEPKEPEPHGVVGGPGENAKPLVLGPEYKQAAQASIKEFGFNMAASDMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLTEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICTVPIIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPREKRLRKTKTEPYRSPAMAGGLFAIERDFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYR-LEGWQGNPPPLYVGSSPTLKNYVRVVEVWWDE-YKDYFYASRPESKALPYGDISELKKFREDHNCKSFKWFMEEIAYDITAHYPLPPRNVEWGEIRGLETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGPDGSKVMITHCNLNEFK-EWQYFKNLHRFTHIASGKCLDRSEVLHQVFISSCDNGKMTQKWEMNNIHSV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VA0-1", "uniprot_id": "GALT7_MOUSE", "id": "Q80VA0-1", "name": "N-acetylgalactosaminyltransferase 7", "aln": "MRLKIGFILRSLLVVGSFLGLVVLWSSLSSRPDDQSPLSRMREDRDVNNPLPNRGGNGLAPGDDRFKPVVPWPHVEGVEVDLESIRRKNKAKNEQERHAGGDSQRDVMQRQYLTFKPQTFTYRDPVLRPGVLGNFEPKEPEPHGVVGGPGEKAKPLVLGPEYKQAVQASIKEFGFNMVASDMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICTVPIIDVISGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTSREKRLRKTKTEPYRSPAMAGGLFAIEKDFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYR-LEGWQGNPPPLYVGSSPTLKNYVRVVEVWWDE-YKDYFYASRPESKALPYGDISELKKFREDHNCKSFKWFMEEIAYDITAHYPLPPRNVEWGEIRGLETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGPDGSKVMITHCNLNEFK-EWQYFKSLHRFTHITSGKCLDRSEVLHQVFISTCDSSKMTQKWEMNNIHSV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SF2-1", "uniprot_id": "GALT7_HUMAN", "id": "Q86SF2-1", "name": "N-acetylgalactosaminyltransferase 7", "aln": "MRLKIGFILRSLLVVGSFLGLVVLWSSLTPRPDDPSPLSRMREDRDVNDPMPNRGGNGLAPGEDRFKPVVPWPHVEGVEVDLESIRRINKAKNEQEHHAGGDSQKDIMQRQYLTFKPQTFTYHDPVLRPGILGNFEPKEPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVASDMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKRLRKTKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYR-LEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDE-YKDYFYASRPESQALPYGDISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDWGEIRGFETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGADGSKVMITHCNLNEFK-EWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTTQKWEMNNIHSV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286YBK3-1", "uniprot_id": "A0A286YBK3_DANRE", "id": "A0A286YBK3-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "MRLKVGFILRSLLVIGTFLGLVLLWSSLTPKAGDDNPFAGVMAREADKLPQPNLPNNNVA---DQFKPVVPWPHVEGVEVDLESIRQKNVDNPNPAFKAQ--NQQNVIQKQYITFKPHTNMYSDPVLNKGTLGNFEPKEPEPHGVQGGPGEGSKPFVLGPEYKDAVQASIKEFGFNMVASDMISLDRTVGDLRHEECKYWNYDENLLTSSVIIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVMIDDFSNKAHLKERLEEYIKQWNGLVKVFRNEKREGLIQARSIGARKATLGKVLIYLDAHCEVGVNWYAPLVAPISKDRTVCTVPLIDSINGKTYTIEAQGGGDEDGFARGAWDWSMLWKRVPLGSKEKQKRLTRTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGQLLFVPCSRVGHIYR-LQGWQGNPPPAHVGSSPTLKNYVRVVEVWWDD-YKDYFYASRPETLTLAYGDISTLKKFREEHRCKSFKWFMEEIAYDIPLHYPLPPKNVEWGEIRGYETSYCIDSMGHTNGGNVEIGPCHRMGGNQLFRINEANQLMQYDQCLTKGGDGSAVIITHCNLNEHT-EWKYFKDLHRFTHVPTGKCLDRSDVLHKVYIADCDNSKSSQKWEMNNIVAV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MV48-1", "uniprot_id": "GALT7_DROME", "id": "Q8MV48-1", "name": "N-acetylgalactosaminyltransferase 7", "aln": "MRVST---IRSGRICRLALCLLVLLPLLYLLANWSDHHKRVQEAYHTRFGGPK------------------------------------------------------FAHQRLEGRPR----EVPKLVDG-LGNFEPKDVKPR---SGPGENGEAHSLSPDKKHMSDASEMEYGMNIACSDEISMHRSVRDTRLEECRHWDYPFDLPRTSVIIVFHNEGFSVLMRTVHSVIDRSPTHMLHEIILVDDFSDKENLRSQLDEYVLQFKGLVKVIRNKEREGLIRTRSRGAMEAT-GEVIVFLDAHCEVNTNWLPPLLAPIYRDRTVMTVPIIDGIDHKNFEYRPVYG--TDNHFRGIFEWGMLYKENEVPRREQRRRAHNSEPYRSPTHAGGLFAINREYFLELGAYDPGLLVWGGENFELSFKIWQCGGSIEWVPCSRVGHVYRGFMPYNFGKLASKKKGPLITINYKRVIETWFDDTHKEYFYTREPLARYLDMGDISEQLALKKRLNCKSFQWFMDHIAYDVYDKFPGLPANLHWGELRSVASDGCLDSMGHQPPAIMGLTYCHGGGNNQLVRLNAAGQLGVGERCVEADRQG--IKLAVCRLGTVDGPWQYNEHTKHLMHRVHKKCMALHPATQQLSLGHCDVNDSYQQWWFKEIRPRW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:. :** : * *::* . * .. . : . *: : :* : :*: * * * *******: :* .**** .:. *.*: *. :** *:*:*:..** **:.*:* * * ***::*.* :* :**:*******:*.*********.*:* : * **:::****:* :*:.:* **: ::*****:**:.*****::** ** :*. *:*:::******* .** .**:*** :***: ***:** *. :.: . * *.. ** ::*.**:*. : :*:: * .:******: *******::::*:*** ***** :*******:*:*******.: :********:** : :: . . .. ** **:*.*:*: :*:***: .* : * **** ::: .****:***:.****: ::* * *:.***:*. : *:****: . : : ** *.***.*:* *.** ::*: . :* : :: *.*. *:* : ::: * **: . ::: :. ** .. *:* :::* . ", "identical_positions": 245, "similar_positions": 175, "identity": "37.07%" }, { "cls_id": "homologset.agr.RGD:620363", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56657-1", "uniprot_id": "CP240_MOUSE", "id": "P56657-1", "name": "Cytochrome P450 2C40", "aln": "----------------------MDPFVVLVLCLSFLLVLSLWRQR--SARGNLPPGPTPLPIIGNYHLIDMKD-----IGQCLTNFSKTYGP---VFTLYFGSQPIVVLHGYEAIKEALIDHGEEFSGRGRIPVFDKVST-GKGIGFSHGNVWKATRVFTVNTLRNLGM------GKRTIENKVQEEAQWLMKELKKTNGSP------------CDPQFIIGCAPCNVICSIVFQNRFD-YKDKDFLSLIGKVNECTEILSSP-GCQIFNAVPILIDYCPGSHNKLFKNHTWIKSYLLGKIKEHEESLDVTN------------PRDFIDYFLIQRRQKNGI----------------------------------EHMDYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDR---NHMPYTNAMVHEVQRYIDLGPNGVVHEVTCDTKFRNYFIPKGTQVMTSLTSVLHDSTEFPNPEVFDPGHFLDDNGNFKKS-DYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDMTPKHSGFSKIPPNFQMCFIPVE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N6C2-1", "uniprot_id": "K7N6C2_MOUSE", "id": "K7N6C2-1", "name": "", "aln": "----------------------MDPFVVLVLCLSFLLLLSLWRQR--SARGNLPPGPTPLPIIGNYHLIDMKD-----IGQCLTNFSKIYGP---VFTLYFGSQPIVILHGYEAMKEAFIDYGEEFSGRGRIPVFDKVSK-GKGIGFSHGNVWKATRVFTVNTLRNLGM------GKRTIETKVQEEAQWLMKELKKTNGSP------------CDPQFIIGCAPCNVICSIVFQNRFD-YKDKDFLSLIGKVNECTEILSSP-ECQIFNAVPILIDYCPGSHNKFLKNHTWIKSYLLEKIKEHEESLDVTN------------PRDFVDYFLIQRRQKNGI----------------------------------EHMDYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDR---NHMPYTNAMVHEVQRYIDLGPNGVVHEVTCDTKFRNYFIPKGTQVMTSLTSVLHDSTEFPNPEVFDPGHFLDDNGNFKKS-DYFMPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDMTPKHSGFSKIPPNFQMCFIPVE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PXC3-1", "uniprot_id": "E9PXC3_MOUSE", "id": "E9PXC3-1", "name": "", "aln": "----------------------MDPFVVLVLCLSFMLLLSLWRQR--SARRNLPPGPTPLPIIGNYHLIDMKD-----IGQCLTNFSKTYGP---VFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSK-GKGIGFSHGNVWKATRVFTVNTLRNLAM------GKRTIENKVQEEAQWLMKELKKTNGSP------------CDPQFIIGCAPCNVICSIVFQNRFD-YKDKDFLSLIGKVNECTEILSSP-GCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTN------------PRDFIDYFLIQRRQDKGI----------------------------------EHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDR---KHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKS-DYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20814-1", "uniprot_id": "CP2CD_RAT", "id": "P20814-1", "name": "Cytochrome P450 2C13, male-specific", "aln": "----------------------MDPVVVLLLSLFFLLFLSLWRPS--SGRGKLPPGPTPLPIIGNFFQVDMKD-----IRQSLTNFSKTYGP---VYTLYVGSQPTVVLHGYEALKEALVDHGEEFSGRGRLPICEKVAK-GQGIAFSHGNVWKATRHFTVKTLRNLGM------GKGTIEDKVQEEAKWLVKELKKTNGSP------------CDPQFIMGCAPGNVICSIILQNRFD-YEDKDFLNLIEKVNEAVKIISSP-GIQVFNIFPILLDYCPGNHNIYFKNHTWLKSYLLEKIKEHEESLDVSN------------PRDFIDYFLIERNQENAN----------------------------------QWMNYTLEHLAIMVTDLFFAGIETVSSTMRFALLLLMKYPHVTAKVQEEIDHVIGRHRSPCMQDR---SHMPYTNAMVHEVQRYIDIGPNGLLHEVTCDTKFRNYFIPKGTAVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGNFKKS-DYFIPFSAGKRMCLGESLARMELFLFLTTILQNFKLKSLVDPKDINTTPICSSLSSVPPTFQMRFIPL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10632-1", "uniprot_id": "CP2C8_HUMAN", "id": "P10632-1", "name": "Cytochrome P450 2C8", "aln": "----------------------MEPFVVLVLCLSFMLLFSLWRQS--CRRRKLPPGPTPLPIIGNMLQIDVKD-----ICKSFTNFSKVYGP---VFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITK-GLGIISSNGKRWKEIRRFSLTTLRNFGM------GKRSIEDRVQEEAHCLVEELRKTKASP------------CDPTFILGCAPCNVICSVVFQKRFD-YKDQNFLTLMKRFNENFRILNSP-WIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNN------------PRDFIDCFLIKMEQEKDN----------------------------------QKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR---SHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKS-DYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q95078-1", "uniprot_id": "CP18A_DROME", "id": "Q95078-1", "name": "Cytochrome P450 18a1", "aln": "MLADSYLIKFVLRQLQVQQDGDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIG-YLLFMGSE-----KHTRFMELAKQYGS---LFSTRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTPFMQTLN--GYGIINSTGKLWKDQRRFLHDKLRQFGMTYM-GNGKQQMQKRIMTEVHEFIGHLHASDGQP------------VDMSPVISVAVSNVICSLMMSTRFS-IDDPKFRRFNFLIEEGMRLFGEI-HTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNN------------IRDLVDFYLCEIEKAKAEGTDAEL----------------------------FDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDL---QYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKP-EYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIA-LPEGQPLPSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V399-1", "uniprot_id": "CP303_DROME", "id": "Q9V399-1", "name": "Probable cytochrome P450 303a1", "aln": "--------------------------MFYTVIWIFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNS-RLGVLLTDGEMWVEQRRFILRHLKNFGF------ARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTR------IEMHDLTSVYVLNTLWCMLSGRRYE-PGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHR--LTYKNYDE---------PRDLMDSYLRAQDE--GNDEK---------------------------------GMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRD--RTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFDG-HLKLP-EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQ--VPEEVPLEGATAAVKPYDIMLVAREQ----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "------------------------MSALIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRS--DLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGT-RKGITCTDGQLWYEHRHFAMKQMRNVGY------GRSQMEHHIELEAEELLGQLERTEEQP------------IEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPA---------ESDLIYAYLQEMKDRSAGGES---------------------------------STFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKD-EYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGE--SPSMVLLPGITLTPKPYKVQFVKRT-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG17-1", "uniprot_id": "CP304_DROME", "id": "Q9VG17-1", "name": "Probable cytochrome P450 304a1", "aln": "------------------------MITETLLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIIN--FKYLHKAALTLSRWYKS--DIIGLHVGPFPVAVVHSADGVREILNNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFILRYLRDFGFG----RRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPLLFNPFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEEGV------------ERNFMDVYIAEMRRGPGYG-------------------------------------FNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDR---KNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLIISPPDFWLQLQDRH-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWR5-1", "uniprot_id": "CP306_DROME", "id": "Q9VWR5-1", "name": "Cytochrome P450 306a1", "aln": "-----MSADIVDIGHTGWMPSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAP-----HKSLQKLAKRYGG---IFELKMGRVPTVVLSDAALVRDFFRRDVMTGRAP--LYLTHGIMG-GFGIICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCAS--------EVNPLPALHHSLGNIINDLVFGITYK-RDDPDWLYLQRLQEEGVKLIGVS-GVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELLLPLG---PSPTLEEL---EPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAP-PQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSGT--EVDMAGESGITLTPTPHMLRFTKLPAVEMRHAPDGAVVQD--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **** * .* . :: : . .* .: : : *: * * :: .. : : : : . * :: : . . . . . : :. :: : * *: . : : : : . : : : * * : . : . .* * .: :: .. : : .* * * ::: **. * : * *: :.* : . . : * . . . : : ", "identical_positions": 27, "similar_positions": 77, "identity": "4.42%" }, { "cls_id": "homologset.agr.RGD:620364", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQR2-1", "uniprot_id": "ADAS_RAT", "id": "Q9EQR2-1", "name": "Alkyldihydroxyacetonephosphate synthase, peroxisomal", "aln": "MAEAAG-------EAGAS-------ERDPDAVRARRRLRVLSGHLLGRPQEAPSTNECKARRAASAAGASPAASPAAPESGTIPKKRQELMKWNGWGYNDSKFLLNKKGQVELTGKRYPLSGLALPTLKDWIQNTLGVNLEHKTTSKPSINPSEAPPSIVNEDFLQELK-EAHISYSQDADDRVFRAHGHCLHEIFLLREGMFERIPDIVVWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQDLERQLKESGYCTGHEPDSLEFSIVGGWISTRASGMKKNVYGNIEDLVVHMKMVTPRGVIEKSSQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPQVSSIFTSFLDGFKKFYITKFKGFDPNQISVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYVVGESFETSAPWDRVIDLCRNVKERIRRECKERGVQFAPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAARDEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPSNIFGNRNLL----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0I1-1", "uniprot_id": "ADAS_MOUSE", "id": "Q8C0I1-1", "name": "Alkyldihydroxyacetonephosphate synthase, peroxisomal", "aln": "MAEAAAG------EAGAS-------ERDPDAGRARRRLRVLSGHLLGRPQEAPSTNECKARRAASAAGASPAATPAAPESGTIPKKRQEVMKWNGWGYNDSKFLLNKKGQVELTGKRYPLSGLVLPTLRDWIQNTLGVSLEHKTTSKTSINPSEAPPSIVNEDFLQELK-EARISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVVWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQDLERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKMVTPRGVIEKSSQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQISVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYIRDLGLEYYVIGESFETSAPWDRVIDLCRNVKERIRRECKERGVQFAPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEHTEAAAREEILANGGSLSHHHGVGKIRKQWLKESISDVGFGMLKSVKEYVDPSNIFGNRNLL----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00116-1", "uniprot_id": "ADAS_HUMAN", "id": "O00116-1", "name": "Alkyldihydroxyacetonephosphate synthase, peroxisomal", "aln": "MAEAAAAAGGTGLGAGASYGSAADRDRDPDPDRAGRRLRVLSGHLLGRPREALSTNECKARRAASAATAAPTATPAAQESGTIPKKRQEVMKWNGWGYNDSKFIFNKKGQIELTGKRYPLSGMGLPTFKEWIQNTLGVNVEHKTTSKASLNPSDTPPSVVNEDFLHDLK-ETNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWVSTRASGMKKNIYGNIEDLVVHIKMVTPRGIIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPVPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNKQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYIRDLALEYYVLGESFETSAPWDRVVDLCRNVKERITRECKEKGVQFAPFSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKEYVDPNNIFGNRNLL----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V778-1", "uniprot_id": "ADAS_DROME", "id": "Q9V778-1", "name": "Alkylglycerone-phosphate synthase", "aln": "---------------------------------------------MAAKRNAVTTEAPESSAPGEGTALALDSRLSKRVESVIPKKRHEALKWFGWGYNDSQFYG-KDGIICFRGEKYPLGGCELPSFTKWVEKKFDLRVD--TTKQYPQLPRTYPRPVENAPFLHELKGTTQVDYSAEGIDRLVRCHGQTLNDIYSLWHHKFRRIPDLVVWPRCHDEVVQLVRLANKHNVMLVPFGGGTSVSGAITCPQNESRMICALDTSQMNRLLWLNRENLTVCFESGIVGQDLERVLRSEGLTVGHEPDSYEFSTLGGWVATRASGMKKNVYGNIEDLVVRVRMVTPSGTLERECSAPRVSCGPDFNHVILGSEGTLGVITEVVLKVRPLPSLRRYGSLAFPNFEQGVLFMREVARRRCQPASVRLMDNEQFMFGQALKPEKS-WWASVVDAMKQRYVTSWKGIDLNQICAATLLFEGDLKDVQRQEALIYEIAEKFQGFPAGGQNGERGYILTFVIAYIRDFGLHQGIVAESFETSVPWDRCSLLCRSVKQRVVSECSKRSINYYTIS-CRVTQTYDAGACIYFYFGFRSTDVADPVELFEAIEHSARDEILSCGGSLSHHHGVGKIRSHWYRNAVTETGSSLYSAAKRHLDPKNIFALGNLLPLEEAQASPPPPTSSTPPKAKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ::* :*: :: ....: : : : ...*****:* :** *******:* *.* : : *::***.* **:: .*:::.:.: :: **.: . * * .: * **::** :.:.** :. **:.*.**: *::*: * . *.****:*:** ***:**::*.** *:*: ::*:******* .: ** :*:* * :********:**::.:***. .*:**.**:*** *:..* .****** *** :***::*********:*********:::**** * :*:....**:* ***::*.*:***********..:*:** *. ::***:********* :**:*::** ***:*****:** **:****: * ::*.:*.:*: *:*.:**:* **:..******** :.* ::* :*:** ** *:.** :**:***:**:****:**:.*. ::.******.**** ***.**:*: **.::.::: .:* *****************.*. .::**: :** * :**:***: ************:*.:* ::::::.* .: .:.* ::**.***. *** ", "identical_positions": 307, "similar_positions": 201, "identity": "45.08%" }, { "cls_id": "homologset.agr.RGD:620365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJ54-1", "uniprot_id": "HNRPD_RAT", "id": "Q9JJ54-1", "name": "Heterogeneous nuclear ribonucleoprotein D0", "aln": "-------------------MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAAA-QGAAAAAGSG---------------------------------------------------SGGG--SAPGGTEGGSTEAEGAKIDASKNEEDEGHSNSSPRHTEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKFG-------------DVVDCTLKLDPITG----RSRGFGFVLFKESESVDKVMDQKE-HKLNGKVIDPKRAKAMKTK-------------EPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKY-HNVGLSKCEIKVAMSKEQYQQQ--QQWGSRGGFAGRARGRGG--GPSQNWN-----------------QGYSNYWNQGYGS---YGYNSQGYGG-YGGYDYTGYNSYYGYGDYSNQQSGYG----------KVSRRGGHQNSYKPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60668-1", "uniprot_id": "HNRPD_MOUSE", "id": "Q60668-1", "name": "Heterogeneous nuclear ribonucleoprotein D0", "aln": "-------------------MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAAAAQGPAAAAGSG---------------------------------------------------SGGGG-SAAGGTEGGSAEAEGAKIDASKNEEDEGHSNSSPRHTEAAAAQREEWKMFIGGLSWDTTKKDLKDYFSKFG-------------EVVDCTLKLDPITG----RSRGFGFVLFKESESVDKVMDQKE-HKLNGKVIDPKRAKAMKTK-------------EPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKY-HNVGLSKCEIKVAMSKEQYQQQ--QQWGSRGGFAGRARGRGG--GPSQNWN-----------------QGYSNYWNQGYGN---YGYNSQGYGG-YGGYDYTGYNNYYGYGDYSNQQSGYG----------KVSRRGGHQNSYKPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14103-1", "uniprot_id": "HNRPD_HUMAN", "id": "Q14103-1", "name": "Heterogeneous nuclear ribonucleoprotein D0", "aln": "-------------------MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAAT-QGAAAAAGSG---------------------------------------------------AGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKFG-------------EVVDCTLKLDPITG----RSRGFGFVLFKESESVDKVMDQKE-HKLNGKVIDPKRAKAMKTK-------------EPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKY-HNVGLSKCEIKVAMSKEQYQQQ--QQWGSRGGFAGRARGRGG--GPSQNWN-----------------QGYSNYWNQGYGN---YGYNSQGYGG-YGGYDYTGYNNYYGYGDYSNQQSGYG----------KVSRRGGHQNSYKPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08473-1", "uniprot_id": "SQD_DROME", "id": "Q08473-1", "name": "RNA-binding protein squid", "aln": "-------------------MAEN-------------------KQVDTEINGEDFTKDVTADGPG---------------------------------------------------SENGDAGAAGSTNG-----------------------SSDNQSAASGQRDDDRKLFVGGLSWETTEKELRDHFGKYG-------------EIESINVKTDPQTG----RSRGFAFIVFTNTEAIDKVSAADE-HIINSKKVDPKKAKARHG------------------KIFVGGLTTEISDEEIKTYFGQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTPK-QKIAGKEVDVKRATPKPENQMMGGMRGGPRGGMRGGRGGYGGRGGYNNQWDGQGSYGGYGGGYGGYGAGGYGDYYAGGYYNGYDYGYDGYGYGGGFEGNGYGGGGGGNMGGGRGGPRGGGGPKGGGGFNGGKQRGGGGRQQRHQPY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P27476-1", "uniprot_id": "NSR1_YEAST", "id": "P27476-1", "name": "Nuclear localization sequence-binding protein", "aln": "MAKTTKVKGNKKEVKASKQAKEEKAKAVSSSSSESSSSSSSSSESESESESESESSSSSSSSDSESSSSSSSDSESEAETKKEESKDSSSSSSDSSSDEEEEEEKEETKKEESKESSSSDSSSSSSSDSESEKEESNDKKRKSEDAEEEEDEESSNKKQKNEETEEPATIFVGRLSWSIDDEWLKKEFEHIG-------------GVIGARVIYERGTD----RSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSKPAGNNDRAKKFGDTPSEPSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKALDALQGEYIDNRPVRLDFSSPRPNNDGG---RGGSRG-FGGRGGGRGG----------------------------------------------NRGFGGRGGARGGRGGFRPSGSGANTAPLGRSR----------NTASFAGSKKTFD--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53883-1", "uniprot_id": "NOP13_YEAST", "id": "P53883-1", "name": "Nucleolar protein 13", "aln": "---MSETELSKEDAVTKKDNEEQVKKALLDPTKKRKAEDEIEIDLKSSIPLSKKQKRLLRRGKVTLEELN----------------------------------------AKYNIDPKSIEEYKEDAEKKKSGASEKDAQGEESTINTPTGDESGEVVKKKKKDENKYGVWIGNLSFDTTKDDLVRFFIAKTKDNEDEKSRVTEQDITRLSMPRVAAKNSNAMKNKGFCYMFFKNVEQMKAVLELSE-SHLNGRNMLIKDSENYSGRP-DKDDLVAMSKNPPSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMATFEDSGKCKGFAFIDFKNEEGSTNALKDKSCRKIAGRPLRMEYGEDRSKRQVRKKVENVSRNNSSSFDISNNK-----------------------------------GYDRAGQDNGSKPEYKRSNANRRPPVDSNNRTKSSVALATAQRGS--------AAIVPSQGKKVKFD--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : . . . .:: .* . : :::* **:. .. * * : : .. :.:*: :: * : . . . : ::.: : . : :*:*.*: : : : * *:: .:.:. .. : :** :: *.. : .. :. . : :. . : : : . .*. . . . : . . * : .. ", "identical_positions": 19, "similar_positions": 87, "identity": "3.85%" }, { "cls_id": "homologset.agr.RGD:620366", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q794E4-1", "uniprot_id": "HNRPF_RAT", "id": "Q794E4-1", "name": "Heterogeneous nuclear ribonucleoprotein F", "aln": "--------------------------------------MMLGPEGGEGYVVKLRGLPWSCSIEDVQNFLSDCTIHDGVAGVHFIYTRE-GRQSGEAFVELESEDDVKLALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPN--GITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRP-----------GTARRYIGIVKQAGLDR------------MRSGAYSAGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTG--------------------------------------------------------------------------------------------------------------------------------------HCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z2X1-1", "uniprot_id": "HNRPF_MOUSE", "id": "Q9Z2X1-1", "name": "Heterogeneous nuclear ribonucleoprotein F", "aln": "--------------------------------------MMLGPEGGEGYVVKLRGLPWSCSIEDVQNFLSDCTIHDGVAGVHFIYTRE-GRQSGEAFVELESEDDVKLALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPN--GITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRP-----------GTARRYIGIVKQAGLDR------------MRSGAYSAGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTG--------------------------------------------------------------------------------------------------------------------------------------HCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52597-1", "uniprot_id": "HNRPF_HUMAN", "id": "P52597-1", "name": "Heterogeneous nuclear ribonucleoprotein F", "aln": "--------------------------------------MMLGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTRE-GRQSGEAFVELGSEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPN--GITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRP-----------GTARRYIGIVKQAGLER------------MRPGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTG--------------------------------------------------------------------------------------------------------------------------------------HCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFJ8-1", "uniprot_id": "F1QFJ8_DANRE", "id": "F1QFJ8-1", "name": "", "aln": "------------------------------------------MADDEGFVVRVRGLPWSCSAEEVSRFFSGCKISSNGSAIHFTYTRE-GRPSGEAFVELESEDDLKIAVKKDRESMGHRYVEVFKSNNVEMDWVLKHTGPNCPETEGDGLVRLRGLPFGCSKEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQDIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYEPPRKGMGMQRPGPYDRPS----------GGGRGYNGMSRGGSFDR------------MRRG----GYGG-----GVSDG----------------------RYGDG-GNFQSTTG--------------------------------------------------------------------------------------------------------------------------------------HCVHMRGLPYRATEPDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGGSNGGYGGQMMGGMGN---QSSY-GHGGQQMGGGYTGGYSSQSSMGGYNDYNSQGGMSNSYYGGSRGSVGMNGMGGGWGM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGH5-1", "uniprot_id": "Q9VGH5_DROME", "id": "Q9VGH5-1", "name": "", "aln": "MSNADVQFNYGQQGNGDNFNDDSNQQQDEDDQYNEDGGGKIENVGESPKFVRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKASMGHRYIEVFTATPKEAKEAMRKISG----HGTAFVVKLRGLPYAVTEQQIEEFFSGLDIKTDREGILFVMDRRGRATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRSSIAEMKRATGAG--GGVGGRPGPYDIRDRGANRGGNDFGGGRNDWGNNGNFGVGANNMLGFNNLPSLMNSGNFGNNQGGNNGNFGNNSGPSNFGNFGGGNNGGNSGNFGNDSGNSGNFGNFGNNGGGNFGGNNNGGGGFNSGNNFNSPGGVNNFGNNGGSNFGGNGGGGFNNGGNFVSSSGVGNFGPIGGGRNNNNGNFGNSGFGNFGGNNNVGSNFGGGNNGGGGGFNNGSNFGGGNSMGGGGNFGPIGGGRGNDIEYYTIHMRGLPYTSFENDVFKFFEPIRPANVRINYNKKGLHSGTADAYFDTYEDSQVAMKRHREQMGSRYIELFYDGKTRGLNG------------------------GEHGGGNGGGGMGNNGGGNFSRRI----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .*::******.: ::: *:.. .: .. :.:*: :* *: :***:**: *::*:: * * :: ******:***.: * . .::: . .*:*****:. ::::* :*****:* .: ** : :* .*: ******** **: :*:** :::*:*******:*:** *:: . ****** * .* * .. *. * . ** * ..* ... ...* : :******* : * *:::**.*:.*..*:*: . .* :* **. * *:*:: .**.:.: :* **:*** :..: . ** . .* .* .:.. *.:. ", "identical_positions": 123, "similar_positions": 124, "identity": "19.1%" }, { "cls_id": "homologset.agr.RGD:620367", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62826-1", "uniprot_id": "RAN_HUMAN", "id": "P62826-1", "name": "GTP-binding nuclear protein Ran", "aln": "---MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDD-DL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62828-1", "uniprot_id": "RAN_RAT", "id": "P62828-1", "name": "GTP-binding nuclear protein Ran", "aln": "---MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDD-DL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62827-1", "uniprot_id": "RAN_MOUSE", "id": "P62827-1", "name": "GTP-binding nuclear protein Ran", "aln": "---MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDD-DL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P79735-1", "uniprot_id": "RAN_DANRE", "id": "P79735-1", "name": "GTP-binding nuclear protein Ran", "aln": "----MAENEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGAIKYNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVEMPALAPPEIAMDPTLAAQYEHDLKVASETALPDEDD-DL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZ23-1", "uniprot_id": "RAN_DROME", "id": "Q9VZ23-1", "name": "GTP-binding nuclear protein Ran", "aln": "---MAQEGQDIPTFKCVLVGDGGTGKTTFVKRHMTGEFEKKYVATLGVEVHPLIFHTNRGAIRFNVWDTAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVAMPALLPPEVKMDKDWQAQIERDLQEAQATALPDEDE-EL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32836-1", "uniprot_id": "GSP2_YEAST", "id": "P32836-1", "name": "GTP-binding nuclear protein GSP2/CNR2", "aln": "MSAPAQNNAEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVASPALAPPEVQVDEQLMHQYQQEMDQATALPLPDEDDADL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32835-1", "uniprot_id": "GSP1_YEAST", "id": "P32835-1", "name": "GTP-binding nuclear protein GSP1/CNR1", "aln": "MSAPAAN-GEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVASPALAPPEVQVDEQLMQQYQQEMEQATALPLPDEDDADL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** *****************:********:**:******* *:** * *:::*******************:.***:********:*****************************:*:******:*.******************************* *:*:**** *** ***: :* * ::::. * .*****: :*", "identical_positions": 160, "similar_positions": 28, "identity": "72.73%" }, { "cls_id": "homologset.agr.RGD:620368", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91W64-1", "uniprot_id": "CP270_MOUSE", "id": "Q91W64-1", "name": "Cytochrome P450 2C70", "aln": "MALFIFLGIWLSCFLFLFLWNQHRGRGKLPPGPTPLPIVGNILQVDVKNISKS-----MGMLAKKYG-PVFTVYLGMKPTVVLHGYKAMKEALIDQGDEFSDKTDSSLLSRTS-QGLGIVFSNGETWKQTRRFSLMVLRSMGMGK--KTIEDRIQEEILYMLDALR------------KTNGSPCDPSFLLACVPCNVISTVIFQHRFDYNDQTFQDFMENFHRKIEILASPWSQLCSAYPILYYLP---GIHNRFLKDVTQQKKFILEEINRHQKSLDLSNP---QDFIDYFLIKME-KEKHNQKSEFTMDNLVVSIGDLFGAGTETTSSTVKYGLLLLLKYPEVTAKIQEEIAHVIGRHRR---PTMQDRNHMPYTDAVLHEIQRYIDFVPIPSPRKTTQDVEFRGYHIPKGTSVMACLTSVLNDDKEFPNPEKFDPGHFLDEKGN-FKKSDYFVAFSAGRRACIGEGLARMEMFLILTNILQHFTLKPLVKPEDIDTKPVQTGLLHVPPPFELCFIPV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19225-1", "uniprot_id": "CP270_RAT", "id": "P19225-1", "name": "Cytochrome P450 2C70", "aln": "MALFIFLGIWLSCLVFLFLWNQHHVRRKLPPGPTPLPIFGNILQVGVKNISKS-----MCMLAKEYG-PVFTMYLGMKPTVVLYGYEVLKEALIDRGEEFSDKMHSSMLSKVS-QGLGIVFSNGEIWKQTRRFSLMVLRSMGMGK--RTIENRIQEEVVYLLEALR------------KTNGSPCDPSFLLACVPCNVISSVIFQHRFDYSDEKFQKFIENFHTKIEILASPWAQLCSAYPVLYYLP---GIHNKFLKDVTEQKKFILMEINRHRASLNLSNP---QDFIDYFLIKME-KEKHNEKSEFTMDNLIVTIGDLFGAGTETTSSTIKYGLLLLLKYPEVTAKIQEEITRVIGRHRR---PCMQDRNHMPYTDAVLHEIQRYIDFVPIPLPRKTTQDVEFRGYHIPKGTSVMACLTSALHDDKEFPNPEKFDPGHFLDEKGN-FKKSDYFMAFSAGRRACIGEGLARMEMFLILTSILQHFTLKPLVNPEDIDTTPVQPGLLSVPPPFELCFIPV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "MSALIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMG-TRKGITCTDGQLWYEHRHFAMKQMRNVGYGR--SQMEHHIELEAEELLGQLE------------RTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGK-CFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAG--ESPSMVLLPGITLTPKPYKVQFVKRT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG17-1", "uniprot_id": "CP304_DROME", "id": "Q9VG17-1", "name": "Probable cytochrome P450 304a1", "aln": "MITETLLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYLHK--AALTLSRWYKSDIIGLHVGPFPVAVVHSADGVREILNNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPLLFNPFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEEGVER---NFMDVYIAEMR----RGPGYGFNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRL---PNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLIISPPDFWLQLQDRH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* :: :**** :* .*. * . :: : :. : :* ..* . . ::* :. : . : . ** :* * : *:* : :*..* *: :* *: : :* :. :: : *. :: . : .: : :: : . . . : : * : :: :* : : *: ::.: . . ::: :: :*. . *. :*:: : *: .. : . :. : * * * :: .:: :. * :. *: : : :* : * * :.* *::: .:: ** ***.: :: .* : * . : :* :* * :*:* *: * : :.*. *:* * *: :** :* . . : *** . *: * : : : ", "identical_positions": 69, "similar_positions": 145, "identity": "13.22%" }, { "cls_id": "homologset.agr.RGD:620369", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0E1-1", "uniprot_id": "HNRPM_MOUSE", "id": "Q9D0E1-1", "name": "Heterogeneous nuclear ribonucleoprotein M", "aln": "MAAGVEAAAEVAATEPKMEEESGAPCVPSGNGAPGPKGE-ERPTQNEKRKEKNIKRGGN-RFEPYSNPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHA--RRAMQKVMATTGG-----------------------MGMGPGGPGMINIPPSILNNPNIPNEIIHALQ-----------------AGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGIVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLSKGIGMGNLGPAGMGMEGIGFG-INKIGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGAGGSVPGIERMGPGIDRISGAG-MERMGAGLGHGMDRVGSEIERMGLVMD---RMG-SVER-MG--SSIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFG-LERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMDRMVP--TGMG-ASLERMG-PVMDRMATGLERMGANNLERM--GLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGAGGASFDRAIEMERGNFGGSFAGS-FGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIK-MENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62826-1", "uniprot_id": "HNRPM_RAT", "id": "Q62826-1", "name": "Heterogeneous nuclear ribonucleoprotein M", "aln": "MAAGVEAAAEVAATEPKMEEESGAPCVPSGNGAPVPKGE-ERPTQNEKRKEKNIKRGGN-RFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHA--RRAMQK-------------------------------------------------------------------------------AGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGIGMGNLGPAGMGMEGIGFG-INKIGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGSGAGGSVPGIERMGPGIDRISGAG-MERMGAGLGHGMDRVGSEIERMGLVMD---RMG-SVER-MG--SGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFG-LERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMDRMVP--TGMG-AGLERMG-PVMDRMATGLERMGANNLERM--GLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGAGGASFDRTIEMERGNFGGSFAGS-FGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIK-MENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52272-1", "uniprot_id": "HNRPM_HUMAN", "id": "P52272-1", "name": "Heterogeneous nuclear ribonucleoprotein M", "aln": "MAAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGN-RFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHA--RRAMQKVMATTGG-----------------------MGMGPGGPGMITIPPSILNNPNIPNEIIHALQ-----------------AGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFG-INKMGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAG-MERMGAGLGHGMDRVGSEIERMGLVMD---RMG-SVER-MG--SGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFG-LERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMERMVP--AGMG-AGLERMG-PVMDRMATGLERMGANNLERM--GLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGS-FGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIK-MENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NZJ3-1", "uniprot_id": "A0A8M1NZJ3_DANRE", "id": "A0A8M1NZJ3-1", "name": "", "aln": "-----------------MSTEASPEKTGQGNAVNG-------KSNHESRKERPPKRGGGGRFEPYSNPNKRYSVFVSNIPYDVKWQTLKDLMKEKVGEVTYVEHLMDGEGKSRGCAVVEFRTEELMKKAVEKVNKHVMNGRPLKVKEDPDGVIS--QREANRGHGGGGGGGGPPGMGGGMGGGMGGGMGGMGMGPGPGSSSMVNIPPSLMNNPNIPNEVIHGLQ-----------------AGKIGSTIFVANLDYKVGWKKLKEVFGMAGMVVRADILEDKDGKSRGMGTVTFDMPIEAVQAVSMFNGQLLFNRVMHVKLDEKSLPKGDFAPPERAPALPRGLSGVGLGLGPGGQPIDATQLNRG-GMGNMGPG--GMDGMGYGGMGRMG--------GMDNFG----------------------------GGGGGGGGMNNMDRFGP-----SGMGRMNDMDRGMGGGFDRDFSGRNDMGMSRS---NFGDSFDRGMGNSMGMDRMN-SGMDRLSGGIDRMGGGGG--GGGMDRMGGGGGGGGMDRMSD-LDRMGSSFDRMGSGLDRLGPSMDRMGSGLDRMSTSVDRMGPGGFDRLGSSSMDRMSGGMDFASPMGMDRMNTGLDRMGSN------FDRMGSGGMDRFSSGLD-RMGSSMDRMG---SGGIGGQFDRPGDMDRGNFGSPFGGSGQGGGPGSGGANARKGCQIFVRNLPFDFTWKMLKDTFNSCGMVQYADIK-MENGKSKGCGVVRFDNPETAERACRTMNGYRLNGREIDVRIDRNA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHC7-1", "uniprot_id": "Q9VHC7_DROME", "id": "Q9VHC7-1", "name": "", "aln": "---------------MSMDASNSVESREKERDRRGRGARGSRFTDADGNGNGAGSQGGGVAARDRSRERRNCRVYISNIPYDYRWQDLKDLFRRIVGSIEYVQLFFDESGKARGCGIVEFKDPENVQKALEKMNRYEVNGRELVVKEDHGEQRDQYGRIVRDGGGGGGGGGGVQGGNGGNNGGGGGGGRDHMDDRDRGFSRRDDDRLSGRNNFNMMSNDYNNSSNYNLYGLSASFLESLGISGPLHNKVFVANLDYKVDNKKLKQVFKLAGKVQSVDLSLDKEGNSRGFAVIEYDHPVEAVQAISMLDRQMLFDRRMTVRLDR-------IPDKNEGIKLPEGLGGVGIGLGPNGEPLRDVAHNLP-------------------------------------------------------------------NGGQSQGQLLGNAQQGSQLGSVGSQPNSSAVSNATTNLLNNLTGVMFGNHAAVQPSP-------------VAPVQKPSLGNNTGSGGLNLNNLNPSILAAVVGNLGNQGGNLSNPLLSSSLSNLGLNLGNSGN-DDNLPPSNVGLSN---------------NYSSGGTGGGNSYSSGNNYSGGG-------------------------GSSNLGYNAYSSSGGMGGGNGGVG-----VDGNDYNTGNPLDVYGGGSNVGNS--NVGSANAVGASRKSDTIIIKNVPITCTWQTLRDKFREIGDVKFAEIR-GND-----VGVVRFFKERDAELAIALMDGSRLDGRNIKVTYF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25555-1", "uniprot_id": "GBP2_YEAST", "id": "P25555-1", "name": "Serine/arginine (SR)-type shuttling mRNA binding protein GBP2", "aln": "-----------------MERELGMYGNDRSRSRSPVRRRLSDDRDRYDDYNDSSSNNGNGSRRQRRDRGSRFNDRYDQSYGGSRYHDDRNWPPRRGGRGRGGSRSFRGGRGGGRGRTLGPIVERDLERQFDATKRN------------------------------------------------------------------------------------------------------------FENSIFVRNLTFDCTPEDLKELFGTVGEVVEADIITSK-GHHRGMGTVEFTKNESVQDAISKFDGALFMDRKLMVRQDN--------PPPEAAKEFSKKATREEIDNG-----FEVFIINLP--------------------------------------------------------------------YSMNWQSLKDMFKECGHVLRADVELDFNGFSRGFGSVIYPTEDEMIRAIDTFN--------------------------------GMEVEGRVLEVREGRFNKRKN----------NDRYNQRREDLEDTRGTEPGLAQD-----------------------------------------------------------------------------------------------------AAVHIDETAAKFTEGVNPGGD--------------RNCFIYCSNLPFSTARSDLFDLFGPIGKINNAELKPQENGQPTGVAVVEYENLVDADFCIQKLNNYNYGGCSLQISYARRD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . . . : : ...*. . . : . ::: :: . * . : . : . ::: : :: : ..:** ** :. :.**::* .* * .*: .* *: **:. : : .. :*:* :: ::::* : *: *. : :.. :. * : . . : . : . . .. . : . . .:: . . . . .. : . : . * ... : * *:*: : . * * * * : *::: :: .**.: . *: . ::. . .* .:.: ", "identical_positions": 36, "similar_positions": 125, "identity": "4.55%" }, { "cls_id": "homologset.agr.RGD:62037", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63053-1", "uniprot_id": "ARC_RAT", "id": "Q63053-1", "name": "Activity-regulated cytoskeleton-associated protein", "aln": "MELDHMTTGGLHAYPAPRGGPAAKPNVILQIGKCRAEMLEHVRRTHRHLLTEVSKQVERELKGLHRSVGKLENNLDGYVPTGDSQRWKKSIKACLCRCQETIANLERWVKREMHVWREVFYRLERWADRLESMGGKYPVGSEPARHTVSVGVGGPEPYCQEADGYDYTVSPYAITPPPAAGELPEQESVGAQQYQSWVPGEDGQPSPGVDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEF-LQYSEGTLSREAIQRELDLPQKQGEPLDQFLWRKRDLYQTLYVDAEEEE-IIQYVVGTLQPKFKRFLRHPLPKTLEQLIQRGMEVQDGLEQAAEPSVTPLPTEDETEALTPALTSESVASDRTQPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV31-1", "uniprot_id": "ARC_MOUSE", "id": "Q9WV31-1", "name": "Activity-regulated cytoskeleton-associated protein", "aln": "MELDHMTTGGLHAYPAPRGGPAAKPNVILQIGKCRAEMLEHVRRTHRHLLTEVSKQVERELKGLHRSVGKLENNLDGYVPTGDSQRWKKSIKACLCRCQETIANLERWVKREMHVWREVFYRLERWADRLESMGGKYPVGSEPARHTVSVGVGGPEPYCQEADGYDYTVSPYAITPPPAAGELPEQESVEAQQYQSWGPGEDGQPSPGVDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEF-LQYSEGTLSREAIQRELELPQKQGEPLDQFLWRKRDLYQTLYVDAEEEE-IIQYVVGTLQPKLKRFLRHPLPKTLEQLIQRGMEVQDGLEQAAEPSGTPLPTEDETEALTPALTSESVASDRTQPE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7LC44-1", "uniprot_id": "ARC_HUMAN", "id": "Q7LC44-1", "name": "Activity-regulated cytoskeleton-associated protein", "aln": "MELDHRTSGGLHAYPGPRGGQVAKPNVILQIGKCRAEMLEHVRRTHRHLLAEVSKQVERELKGLHRSVGKLESNLDGYVPTSDSQRWKKSIKACLCRCQETIANLERWVKREMHVWREVFYRLERWADRLESTGGKYPVGSESARHTVSVGVGGPESYCHEADGYDYTVSPYAITPPPAAGELPGQEPAEAQQYQPWVPGEDGQPSPGVDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEF-LQYSEGTLSREAIQRELDLPQKQGEPLDQFLWRKRDLYQTLYVDADEEE-IIQYVVGTLQPKLKRFLRHPLPKTLEQLIQRGMEVQDDLEQAAEPAGPHLPVEDEAETLTPAPNSESVASDRTQPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7JV70-1", "uniprot_id": "ARC2_DROME", "id": "Q7JV70-1", "name": "Activity-regulated cytoskeleton associated protein 2", "aln": "--------------------------------------------------------------------------------------------------------MTQMSDEQFRIFIETIKSLG-------------PIKEE----------------------------------PPSKGSFSNCTVRFSGQRD------------------HDAVDEFINAVETYKEVEGISDKDALKGLPLLFKSIAVVWWKGVRRDAKTWSDALQLLRDHFSPTKPSYQIYMEIFETKQSYDEVIDSFICKQRALLAKLPEGRHDEETELDFIYGLMQPKYRESIPRHEVKTFRELLDRGRTVERTRH------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ..::::: *.: * *: .* **: *.:. : * : .: **:. :* * . * *:: *. : ::. * **: : ..*.* : : : ::* . * : . :: *. .* :*.*: ::* * .* . .:** :::: * :*** :. : : **:.:*::** *: . ", "identical_positions": 41, "similar_positions": 74, "identity": "10.3%" }, { "cls_id": "homologset.agr.RGD:620370", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24470-1", "uniprot_id": "CP2CN_RAT", "id": "P24470-1", "name": "Cytochrome P450 2C23", "aln": "--------------------MELLGFTTLALVVSVTCLSLLSVWTKLRTR----GRLPPGPTPLPIIGNLLQLNLKDIPAS-----LSKLAKEYGP---VYTLYFGTSPTVVLHGYDVVKEALLQQGDEFLGRGPLPIIEDTHK-GYGLIFSNGERWKVMRRFSLMTLRNFGMG------KRSLEERVQEEARCLVEELQKTKAQP------------FDPTFILACAPCNVICSILFNDRFQYNDKTFLNLMDLLNKNFQQVNSVWCQMYNLWPTIIKYLP--GKHIEFAKRIDDVKNFILEKVKEHQKSLDPAN------------PRDYIDCFLSKIEE-EKDNLKSEFH---------------------------------LENLAVCGSNLFTAGTETTSTTLRFGLLLLMKYPEVQAKVHEELDRVIGRHQPPSMKDK---MKLPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRDYVIPKGTTVLPMLSSVMLDQKEFANPEKFDPGHFLDKNGCFKKT-DYFVPFSLGKRACVGESLARMELFLFFTTLLQKFSLKTLVEPKDLDIKPITTGIINLPPPYKLCLVPR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5K4-1", "uniprot_id": "CP2CN_MOUSE", "id": "E9Q5K4-1", "name": "Cytochrome P450 2C44", "aln": "--------------------MELLGLPTLALLVLVMSLSLLSVWTKMRTG----GRLPPGPTPLPIIGNILQLDLKDIPAS-----LSKLAKEYGP---VYTLYFGSWPTVVLHGYDVVKEALLNQGDEFLGRGPLPIIEDSQK-GHGIVFSEGERWKLLRRFSLMTLKNFGMG------KRSLEERVQEEARCLVEELHKTEAQP------------FDPTFILACAPCNVICSILFNERFPYNDKTFLNLMDLLNKNFYQLNSIWIQMYNLWPTIMKYIP--GKHREFSKRLGGVKNFILEKVKEHQESLDPAN------------PRDYIDCFLSKIEE-EKHNLKSDFN---------------------------------LENLAICGSNLFTAGTETTSTTLRFGLLLLVKHPEVQAKVHEELDRVIGRHQPPSMKDK---MKLPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRHYVIPKGTAVFPFLSSILLDQKEFPNPEKFDPGHFLDKNGCFKKT-DYFVPFSLGKRSCVGEGLARMELFLFFTTILQKFSLKALVEPKDLDIKPVTTGLFNLPPPYKLRLVPR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V399-1", "uniprot_id": "CP303_DROME", "id": "Q9V399-1", "name": "Probable cytochrome P450 303a1", "aln": "--------------------------MFYTVIWIFCATLLAILFGGVRKP----KRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNS-RLGVLLTDGEMWVEQRRFILRHLKNFGFA------RSGMMDIVHNEATCLLQDLKDKVLKSGGKQTR------IEMHDLTSVYVLNTLWCMLSGRRYE-PGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHR--LTYKNYDE---------PRDLMDSYLRAQDE--GNDEKGMFS---------------------------------DQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRD--RTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFDG-HLKLP-EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPG--QVPEEVPLEGATAAVKPYDIMLVAREQ----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "------------------------MSALIFLCAILIGFVIYSLISSARRP----KNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRS--DLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGT-RKGITCTDGQLWYEHRHFAMKQMRNVGYG------RSQMEHHIELEAEELLGQLERTEEQP------------IEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPA---------ESDLIYAYLQEMKDRSAGGESSTFN---------------------------------ETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKD-EYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAG--ESPSMVLLPGITLTPKPYKVQFVKRT-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q95078-1", "uniprot_id": "CP18A_DROME", "id": "Q95078-1", "name": "Cytochrome P450 18a1", "aln": "MLADSYLIKFVLRQLQVQQDGDAQHLLMVFLGLLALVTLLQWLVRNYREL----RKLPPGPWGLPVIGYLLFMGSEKHTRF------MELAKQYGS---LFSTRLGSQLTVVMSDYKMIRECFRREEFTGRPDTPFMQTLN----GYGIINSTGKLWKDQRRFLHDKLRQFGMTYM-GNGKQQMQKRIMTEVHEFIGHLHASDGQP------------VDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHT--VDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNN------------IRDLVDFYLCEIEKAKAEGTDAELFDGKNH----------------------------EEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDL---QYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKP-EYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEG-QPLPSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG17-1", "uniprot_id": "CP304_DROME", "id": "Q9VG17-1", "name": "Probable cytochrome P450 304a1", "aln": "------------------------MITETLLTICAAVFLCLSYRYAVGRP----SGFPPGPPKIPLFGSYLFMLIINFKYLHK--AALTLSRWYKS--DIIGLHVGPFPVAVVHSADGVREILNNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFILRYLRDFGFG----RRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPLLFNPFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEEGV------------ERNFMDVYIAEMRRGPGYGFN-------------------------------------RDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDR---KNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLIISPPDFWLQLQDRH-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWR5-1", "uniprot_id": "CP306_DROME", "id": "Q9VWR5-1", "name": "Cytochrome P450 306a1", "aln": "---------MSADIVDIGHTGWMPSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKS-----LQKLAKRYGG---IFELKMGRVPTVVLSDAALVRDFFRRDVMTGR--APLYLTHGIMG-GFGIICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCAS--------EVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIG--VSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELLLPLG---PSPTLEEL---EPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAP-PQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSG--TEVDMAGESGITLTPTPHMLRFTKLPAVEMRHAPDGAVVQD--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **** * .* . :: : . .* ..: : : .: . *: * *: :: .* : : : : . . * :: . * : . : : : :. : : . .* :: .. : : : : . : : : * * : . .: . * * .: :. .. : : .* .* * ::: **. * : * *: :.* : . . : * . * . : : ", "identical_positions": 29, "similar_positions": 84, "identity": "4.72%" }, { "cls_id": "homologset.agr.RGD:620371", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLT7-1", "uniprot_id": "RX_RAT", "id": "Q9JLT7-1", "name": "Retinal homeobox protein Rx", "aln": "------------------------------------------------MHLPG-----CPPAMADGSFS--------LAGHLLR----------------------SPGGSTSRLHSIEAILGFTKED--------------------------------------------------------------------------------------------------------------GILDTFPAERSSRGSKERDPRLG-------ARSACPKAPAGGSESSPPAAPGLVPEFEATRPCYPKEQGEARPS--------------------------------------------------------------------------------------------PGLPVGPAAGD--------------------------------------------------------------------------------------------SKLS-------EEEEPPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEK---------------------------------------------------------LEVSSMKLQDSPLLSFSRSPPSSALAPLG-GPGSGSGPPGSALP-------------------LEPWLG--PPLPGGGATALQSLPGFGPPGQG-LPASYTPPPP---FLNSAPLGPGLQQLGPPP-AYPCAPAFGDKFS----------LEEAYP---------------------------------------------RNSSIAALRLKAKEHIQAIGKPWQAL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35602-1", "uniprot_id": "RX_MOUSE", "id": "O35602-1", "name": "Retinal homeobox protein Rx", "aln": "------------------------------------------------MHLPG-----CAPAMADGSFS--------LAGHLLR----------------------SPGGSTSRLHSIEAILGFTKED--------------------------------------------------------------------------------------------------------------GILDTFPAERSSRSSKERDPRLG-------AQPACPKAPAGGSESSPPAAPGFVPEYEATRPCYPKEQGEARPS--------------------------------------------------------------------------------------------PGLSVGPAAGD--------------------------------------------------------------------------------------------SKLS-------EEE-PPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEK---------------------------------------------------------LEVSSMKLQDSPLLSFSRSPPSSALAPLGTGPGSGSGPPGSALP-------------------LEPWLG--PPLPGGGATALQSLPGFGPPGQG-LPASYTPPPP---FLNSAPLGPGLQQLGPPP-AYPCAPAFGDKFS----------LEEAYP---------------------------------------------RNSSIAALRLKAKEHIQAIGKPWQAL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2V3-1", "uniprot_id": "RX_HUMAN", "id": "Q9Y2V3-1", "name": "Retinal homeobox protein Rx", "aln": "------------------------------------------------MHLPG-----CAPAMADGSFS--------LAGHLLR----------------------SPGGSTSRLHSIEAILGFTKDD--------------------------------------------------------------------------------------------------------------GILGTFPAERGARGAKERDRRLG-------ARPACPKAPEEGSEPSPPPAPAPAPEYEAPRPYCPKEPGEARPS--------------------------------------------------------------------------------------------PGLPVGPATGE--------------------------------------------------------------------------------------------AKLS-------EEE-QPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEK---------------------------------------------------------LEVSSMKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALP-------------------LESWLG--PPLPGGGATALQSLPGFGPPAQS-LPASYTPPPPPPPFLNSPPLGPGLQPLAPPPPSYPCGPGFGDKFP----------LDEADP---------------------------------------------RNSSIAALRLKAKEHIQAIGKPWQAL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O42358-1", "uniprot_id": "RX3_DANRE", "id": "O42358-1", "name": "Retinal homeobox protein Rx3", "aln": "------------------------------------------------MRLVG-----SQYKDMEDRLS--------PSARLVR----------------------SPG-SQTRIHSIESILGFKGET--------------------------------------------------------------------------------------------------------------LFHPAFPYGSGKTG--KDTEHLS-------PKKDSNKHFDGVCRST------------------------VMVS--------------------------------------------------------------------------------------------PDL---PDADG--------------------------------------------------------------------------------------------GKLS-------DDE-NPKKKHRRNRTTFTTFQLHELERAFEKSHYPDVYSREELALKVNLPEVRVQVWFQNRRAKWRRQEK---------------------------------------------------------LEVSSIKLQESSMLSIPRS-----------GPLS----LGSGLP-------------------LEPWLT--GPISTS-SSPLQSLPSFITPQQA-VPASYTPPQ----FLSSSTLNHSLPHIGAVCPPYQCS-GFMDKFS----------LQEADP---------------------------------------------RNTSIASLRMKAKEHIQSIGKTW----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2Q1-1", "uniprot_id": "RX_DROME", "id": "Q9W2Q1-1", "name": "Retinal homeobox protein Rx", "aln": "MSGSGGVANSSSTAAANNTAATFQHIFEQLVQQGGGNHKLPPKQLEQLRHLLGNVRDAKNLQMIVEKFKNLEQFHEHYAAHLANNNTVISTEDSNDLVKDNARKYGSGGQTLTPRHTIDAILGLKNRNGAANGSGRNPETVSDGSVDPSLGDDDATDLRCGMTLTQLRSMDNHMASMLQQHAKNGGALPYGPPTPPGGQQPQVPNATPLHHGQQMGGQAGHATHAGHGHPTHHGHAPFGYHNAFGFGQGGHGYGHPEEAAGNYLNSMHQMVEANQLQTGANGANPPPAPLPPSSFGSHQQHLAALAAQAQEQQNQHSKYAKSSPTGAGPPPPPGAYFMESQTAPVAPSQINYDERSMSSASDLEEDDDDAAKLQLDVTSPPTPSPRGQLAAKRKSAGVFCDDNEPKLANGQLPGGNYGIRPRSMEEVHHQQQSHHHQQQQQQQQQQQQLQQQQGFQHDFRNSGNGNPNGNSNSGDHGERLNADSDSLVNGSCASSEDLNQTNSSEQGEKITSGSDDEGQDDNCAKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKSESLRLGLTHFTQLPHRLGCGASGLPVDPWLSPPLLSALPGFLSHPQTVYPSYLTPPLSLAPGNLTMSSLAAMGHHHAHNGPPPPHVGHGGHGQPQPPPPPPPHGVPHPHGSHHVVPLSHLSPHLSRMSPHATSLGSPHHGVTPLGTPLHSSLPPSSTATTVAVSSSQSSSSSASLECSGPDVCMSPQNLSIGNADSNGDGRDLSSDLDAGSTSSNPGSSLDKCAASANIELLDVGRDSPPPPPTPTGKGSSTPPTDMRSNSIATLRIKAKEHLDNLNKGMVSIV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * :. :.:* . * * : : *:*::***:. :* . . . . . : .. . . * * .. *:: ::: .*************:************************ ************************* *.::. :* *.: :: : * . * *.. * * . . .:. :.:. : .* :. :*.* *.. .*.. . .* .. .: : . *: . . *..***:**:*****:: :.* ", "identical_positions": 103, "similar_positions": 86, "identity": "11.8%" }, { "cls_id": "homologset.agr.RGD:620372", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IMY8-1", "uniprot_id": "HNRPU_RAT", "id": "Q6IMY8-1", "name": "Heterogeneous nuclear ribonucleoprotein U", "aln": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKADLMDRLQAALDN-EAGGR-PAMEPGNGSLDLGGDAAGRSGAGLEQEAAAG-----AEDDEEEEGIAALDGDQMELGEENGAAGAADAGAMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQSQPPAAA--QQASQQRGPGKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGG-------------------DGKTEQKAGDKKRGVKRPREDHGRG------------YFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLS-ASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVR--HLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFETDEVELSYAKNGQDLGVAFKISKEVLADR-PLFPHVLCHNCAVEFNFGQKEKPYFPIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDCTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVE-GKDLPEHAVLKMKGNFTLP-EVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSN----KNKSGKNQFN------------------------------RGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGG-SGGIGYPYPRGPVFPGRGGYSNRGNYNRGG------MPNRGNYNQNFRGRGNNRGYKNQSQGYN----------------------------------------------------------------------------------------------------QWQQGQFWGQKPWSQHYHQGYY----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VEK3-1", "uniprot_id": "HNRPU_MOUSE", "id": "Q8VEK3-1", "name": "Heterogeneous nuclear ribonucleoprotein U", "aln": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKADLMDRLQAALDN-EAGGR-PAMEPGNGSLDLGGDAAGRSGAGLEQEAAAG-----AEDDEEEEGIAALDGDQMELGEENGAAGAADAGAMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQSQPPAAAAQQQPSQQRGAGKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGG-------------------DGKTEQKGGDKKRGVKRPREDHGRG------------YFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLS-ASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVR--HLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFETDEVELSYAKNGQDLGVAFKISKEVLADR-PLFPHVLCHNCAVEFNFGQKEKPYFPIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDCTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVE-GKDLPEHAVLKMKGNFTLP-EVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSN----KNKSGKNQFN------------------------------RGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGG-SGGIGYPYPRGPVFPGRGGYSNRGNYNRGG------MPNRGNYNQNFRGRGNNRGYKNQSQGYN----------------------------------------------------------------------------------------------------QWQQGQFWGQKPWSQHYHQGYY----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00839-1", "uniprot_id": "HNRPU_HUMAN", "id": "Q00839-1", "name": "Heterogeneous nuclear ribonucleoprotein U", "aln": "MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGR-PAMEPGNGSLDLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQ-QQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGGDKKRGVKRPREDHGRG------------YFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLS-ASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVR--HLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVAFKISKEVLAGR-PLFPHVLCHNCAVEFNFGQKEKPYFPIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEYTFIQNVPLEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVE-GKDLPEHAVLKMKGNFTLP-EVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPEKKQNTGSKKSN----KNKSGKNQFN------------------------------RGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGG------MPNRGNYNQNFRGRGNNRGYKNQSQGYN----------------------------------------------------------------------------------------------------QWQQGQFWGQKPWSQHYHQGYY----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1JGL8-1", "uniprot_id": "E1JGL8_DROME", "id": "E1JGL8-1", "name": "", "aln": "--MDVAKLEKMKVVDLRNELQSRGLDTKGVKAVLVERLRAYVEGGAGDGENAPVTPSRRQRRTRSMSRSPSPVQAAPVAAEPVLDTLEEEEQPEDKTVPQPEPESEQPAAEPEPEQSEPEEAEPAAAVTEDTTVNQAVNEESQPEPEEFDEKSETDDKQETIEEAVPAVVPQNEVADEPMEEDHDAAPEEQEPTQTEEPVEEKPAESTVAEHQSNGDSQKMDVDEEDSAAPKTAEETEPAAKPEDQPPERRKRSHSRSKSRSRSGSRSSKHRGSVGDKRESKAAAEERTVPEDEPTIEENKVGLSWLDSDLHLRIDPTTFASAKPLTSEIYSLIWSGARANYGVREGKVCFEVRLSEESVPENSHYFRDEPHVRGFRVGFSMPKSSLLLGEAEHSFGYCETGRKATQSEFTDYGKPYQLDDVIGCYLDLESEPCTINYTLNGEDLGVAFEFEKSILGEEGALFPHIVTKGYEYLVNFSDTEQLLVNAERPTRKRRKPRKDEDKDKDDDKDDNDGEKWKVLDEATADDDEVEKKDEDGKASSEKDEEEAEDPEKAKEDEAAPKTETEAETKVEAPAEAAKPESEATEASETAETSTEKSSETAAVSNGDAAAEQANDEKASEDKKPSENNDEEDEDGPSPNKRPKTDGDSEKAESEKEKDRSQTTEDEYEDVVPEPRDTAALLEGYVLIGLVPVEKLVSGPQRVGSRKECEVILLVGLPGAGKTHWAHKHVAENADKRYELIGPDAFISKMTIDGASRKTVHKGRWDKVYEICLNSLAALEDIAMKRRRNFILDQTNVYASAQRRKMKGFNDFKRIAVVCIPSEDELKRRIAEKEEKGNAFTVKESTINNLRANFTLPSLEFGWFDDINYTELTGDEAKSEVKKYNEKGKKAIDAERSRDKRSRGSRDNYRRDDRNRNRYNDDRRRDYGGQRHESRWSDSRRGGGGGGYSSNSGGGGSRGYDNRRNYNSGSGGQQNWVQNSRRSGYDDRGYGGGGSGSRGYDNRNRGYAGGSGGGGGGGGGGGGGGGQQNWMQNNRRSGYDDRGYGSSRDYRDRDRGNDRSRMGSNDRNRGSSQSSYRSGGGTHQQRDFRPGHRDTKEDSRGGYERSAGQSLPKYGNNTAVGGGYDQYKQQGGAPGGGKASLSGKWSTYSQHHQQQQAPQHQQTGIWQTQQQSQQYQQPQQAAAGQQQYWAYNQMQTGYGNQQAWQSADPQQQQQWMSWWQQQQQGSGGAAAGNASGGSGVNVGGGAGNNDGGAANHYWSQYSYSTQSNAGADKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:::*:** :*::**:.* *. **:** *::**:* ::. ..*. ..: *.. . . : . * . ** *::: *: . : * : . ::. * *.:** . :: :*.: * : :* : :: : : **. :: :: .. *. .. .: .* *.. : . :** . :.: :* :..*.*. : : ::: *:* : : .* *:: :::. * *. :.***::*. :: *..** * ::::*:*.**.*** :******::::*: . * : .: .:: .*:*:*:..*.:**** *.*:**. .* *: :.* ***: :: :*** *: ::*:: :.*: **:******::.*.:*. . .****:: :. .**.:.*: . * .:* **:*. * **: .:*:***::::******** *. **.***..* *:::*.::::.** : * .:: ...*: :.: : . :.*. : :** :::********** *:****** * .*:* *** *.::: *:* :* * . : * :: :::.***** **:*.*.** :**:. :::*:*:.***: .*:.::. *: *. ::. .:*::* ..** .** * *. * .*. * .**.. :** *** **. ** . * *. .. *. . ** * *. . . : ** *..*.*:::.:* : * ** :* : **:*:* ", "identical_positions": 240, "similar_positions": 302, "identity": "18.84%" }, { "cls_id": "homologset.agr.RGD:620373", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91Z62-1", "uniprot_id": "FBX32_RAT", "id": "Q91Z62-1", "name": "F-box only protein 32", "aln": "MPFLGQDWRSPGQSWVKTADGWKRFLDEKSGTFVSDLSSYCN-----KENLFNSLNYDVAAKKRKKDIQNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTLVQRVGKSVLVGNINMWVYRMETTLHWQQQLNSIQISRPAFKG-LTITDLPVCLQLNIMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKRLCQYHFSERQIRKRLILSDKGQL----DWKKMYFKLVRCYPRRE--QYGVTLQLCKHCHILSWKGTDHPCTANNPE-------------SCSVSLSPQDFINLFKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPU7-1", "uniprot_id": "FBX32_MOUSE", "id": "Q9CPU7-1", "name": "F-box only protein 32", "aln": "MPFLGQDWRSPGQSWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYSKENLFSSLNYDVAAKKRKKDIQNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNSIQISRPAFKG-LTITDLPVCLQLNIMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKRLCQYHFSERQIRKRLILSDKGQL----DWKKMYFKLVRCYPRRE--QYGVTLQLCKHCHILSWKGTDHPCTANNPE-------------SCSVSLSPQDFINLFKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969P5-1", "uniprot_id": "FBX32_HUMAN", "id": "Q969P5-1", "name": "F-box only protein 32", "aln": "MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYNKENLFNSLNYDVAAKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKG-LTFTDLPLCLQLNIMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQL----DWKKMYFKLVRCYPRKE--QYGDTLQLCKHCHILSWKGTDHPCTANNPE-------------SCSVSLSPQDFINLFKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTM4-1", "uniprot_id": "Q9VTM4_DROME", "id": "Q9VTM4-1", "name": "F-box only protein 32", "aln": "MAFISKDFRSPGETWIKTDGGWERSKVLECG-----------------------GKRKRHHSEGSSSYQDSDSSEEEAVMPPHYHITIRCTREIAGFNGLSEAVKRLDFRRSVRDRKRFHYICAFLLLVSNKGIASLPGSAQRQLLQMVEEVASHVNDSQQHPNVLRGLALKLEHIVSQENQKCWG-KPLGSTYLWKEHMATIKRIQRVASQIEIREPDPEAKPKLHELPEECVREIILCIADHRDLESAAEAWETMAKLVSEQRIWRELTRFHFNQRQIHTILDLDKFKQMGEIKDWKQIYHQLRRTYGVNDDYQFAEVLALCRSCCCLFWPSDGHPCIVDQSPDYKQRLEEAGGQLALAQPVPPAQFLKYFSL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*:.:*:****:.*:** .**:* :.* : . .: ... :*.:. : :: .*:* *: *.**.:**** :: * :**:*: :* *:::. ::**.* **:::::::*:*. :* :.**: .::* * .* :. *: :*. :* :* * : *: ..*:* .* :. .: :** :*: ::* *** * .:* : * .:: :*:.* ::**.:***:. * *.. *: ***::*.:* * * .: *:. .* **: * * * . .*** .::. : : .:.* :*:: *.:", "identical_positions": 93, "similar_positions": 128, "identity": "24.8%" }, { "cls_id": "homologset.agr.RGD:620374", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z340-1", "uniprot_id": "PARD3_RAT", "id": "Q9Z340-1", "name": "Partitioning defective 3 homolog", "aln": "--------------------MKVTVCFGRTRVVVPCGDGRMKVFSLIQQAVTRYRKAVAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDP-----HHGGDGTS-ASSTGTQSPEIFGSELGTNN-VSAFRPYQTTSEIEVTPS--VLRANMPLHVRRSSDPALTGLS-TSVSDNNFSSEEPSRKNPTRWSTTAGFLKQNTTGSPKTCDRKKD--ENYRSLPRDPSSWSN--QFQRDNARSSLSASHPMVDRWLEKQEQDEEGTEEDSSRVEPVGHADTGLENMPNFSLDDMVKLVQVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEQENLFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARVIWFHVVPAANKEQYEQLSQREMNNYS----PGRFSPDSHCVANRSVANNAPQALPRAPRLSQPPEQLDAHPRLPHSAHASTKPPTAPALAPPNVLSTSVGSVYNTKRVGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQE-------------------------------------------------EAFHPREMNAEPSQMQSPKETKAEDEDIVLTPD--GTREFLTFEVPLNDSGSAGLGVSVKGNRSK-----------------ENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKANQEAMETLRRSMS-TEGNKRGMIQLIVARRISRCNELR--------------------------------SPGSPAAPELPIETELDDRERRISHSLYSGIEGLDESPTRNAALS-RIMGESGKCQLSPTVNMPH----------------------------------------------------DDTVMIEDDRLPVLP-----PHLSDQSSSSSHDDVGFIMTEAGTWAKATISDSADCSL-----------SPDVDPVLAFQREGFGRQSMSEKRTKQFSNASQLDFVKTR-----KSKSMDLGIADETKLNTVDDQRAGSPNRDVGPSLGLKKSSSLESLQTAVAEVTLNGNIPFHRPRP-RIIRGRGCNESFRAAIDKSYDKPMVDDDDE-GMETLEEDTEESSRSGRESVSTSSDQPSYSLERQMNGDPEKRDKAEKKKDKAGKDKKKDREKEKDKLKAKKG-MLKGLGDMFRFGKHRKDDKMEKMGRIKIQDSFTSEEDRVRMKEEQERIQAKTREFRERQARERDYAEIQDFHR---TFGCDDELLYGGMSSYDG--CLALNARPQSPREGHLMDTLYAQVKKPRSSKPG--DSNRSTPSNHDRIQRLRQEFQQAKQDE-DVEDRRRTYSFEQSWSSSRPASQSGRHSVSVEVQVQRQRQEERESFQQAQRQYSSLPRQSRKNASSVSQDSWEQNYAPGEGFQSAKENPRYSSYQGSR------------NGYLG---------GHGFNARVMLETQELLRQEQRRKEQQLKKQPPADG-----------------VRGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99NH2-1", "uniprot_id": "PARD3_MOUSE", "id": "Q99NH2-1", "name": "Partitioning defective 3 homolog", "aln": "--------------------MKVTVCFGRTRVVVPCGDGRMKVFSLIQQAVTRYRKAVAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDP-----HHGGDGTS-ASFTGTQSPEIFGSELGTNN-VSAFQPYQATSEIEVTPS--VLRANMPLHVRRSSDPALTGLS-TSVSDNNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKD--ENYRSLPRDPSSWSN--QFQRDNARSSLSASHPMVDRWLEKQEQDEEGTEEDSSRVEPVGHADTGLENMPNFSLDDMVKLVQVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEQENLFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARVIWFHVVPAANKEQYEQLSQREKNNYS----PGRFSPDSHCVANRSVANNAPQALPRAPRLSQPPEQLDAHPRLPHSAHASTKPPAAPALAPPSVLSTNVGSVYNTKKVGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQE-------------------------------------------------EAFHPREMNAEPSQMQTPKETKAEDEDVVLTPD--GTREFLTFEVPLNDSGSAGLGVSVKGNRSK-----------------ENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKANQEAMETLRRSMS-TEGNKRGMIQLIVARRISRCNELR--------------------------------SPGSPAAPELPIETELDDRERRISHSLYSGIEGLDESPTRNAALS-RIMG---KCQLSPTVNMPH----------------------------------------------------DDTVMIEDDRLPVLP-----PHLSDQSSSSSHDDVGFIMTEAGTWAKATISDSADCSL-----------SPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTR-----KSKSMDL-VADETKLNTVDDQRAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGNIPFHRPRP-RIIRGRGCNESFRAAIDKSYDKPMVDDDDE-GMETLEEDTEESSRSGRESVSTSSDQPSYSLERQMNGDPEKRDKTERKKDKAGKDKKKDREKEKDKLKAKKG-MLKGLGDMFRFGKHRKDDKMEKMGRIKIQDSFTSEEDRVRMKEEQERIQAKTREFRERQARERDYAEIQDFHR---TFGCDDELLYGGMSSYEG--CLALNARPQSPREGHLMDTLYAQVKKPRSSKPG--DSNRSTPSNHDRIQRLRQEFQQAKQDE-DVEDRRRTYSFEQSWSSSRPASQSGRHSVSVEVQVQRQRQEERESFQQAQRQYSSLPRQSRKNASSISQDSWEQNYAPGEGFQSAKENPRYSSYQGSR------------NGYLG---------GHGFNARVMLETQELLRQEQRRKEQQLKKQPPADG-----------------VRGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEW0-1", "uniprot_id": "PARD3_HUMAN", "id": "Q8TEW0-1", "name": "Partitioning defective 3 homolog", "aln": "--------------------MKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDP-----HHGGDGTS-ASSTGTQSPEIFGSELGTNN-VSAFQPYQATSEIEVTPS--VLRANMPLHVRRSSDPALIGLS-TSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKD--ENYRSLPRDTSNWSN--QFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYY----SSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQE-------------------------------------------------DAFHPRELNAEPSQMQIPKETKAEDEDIVLTPD--GTREFLTFEVPLNDSGSAGLGVSVKGNRSK-----------------ENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMS-TEGNKRGMIQLIVARRISKCNELK--------------------------------SPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALS-RIMGESGKYQLSPTVNMPQ----------------------------------------------------DDTVIIEDDRLPVLP-----PHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSL-----------SPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTR-----KSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRP-RIIRGRGCNESFRAAIDKSYDKPAVDDDDE-GMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKG-MLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHR---TFGCDDELMYGGVSSYEG--SMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDE-DVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSR------------NGYLG---------GHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9K4-1", "uniprot_id": "A0AB13A9K4_DANRE", "id": "A0AB13A9K4-1", "name": "", "aln": "--------------------MKVTVCFGRTRVVVPCGDGNIKVQSLVQQAAMRYRRAIAKGEEYWVQVYRLEHGDGGILDLDDVLCDVADDKDRLVAVFDEQEP-----HVGGDGTS-ASSTGTQSPELYCGEPSTSTPLSAFQPYLPHSEIEVTTS--TLRTNMPLHVRRSSDPALLNLTAMSFSEPGSQPEEPSRKNPTRWSTTAGFLKPRFATGTNSLERKGRGVDTYRSLPRDAGQWSNQKEFQREKARSSLSANHPMVDRWLERQEQD----EEENGRIEPVGRADTCLEHMGVRSLDDIVKLVEVSNDGGPLGIHVVPFSGRDRRTLGLLVKRLERGGKADVQGLFQENDCIIRINNGDLRNVRFEQAQNMFRQAMRSPVILFHVVPTTMRSQYEQISHNEHNPRANIDLSGRFSPDSLTNDLDSAAHRLAQHRP-----QQPNNHLDTGSPVHHLVGSSGKPPTGHTSSPQRGLSPAPTTGF-TKKVGRRLGIQLKKGPEGLGFSITSRDVPLGGSAPIYVKNILPRGAAIQDGRLKAGDRLLEVNGVDLNGRGQEEVVSLLRATPMGGTVTLVVLRQE-------------------------------------------------ETFIPREMNAEP-AIQNTREWKVEEEELVLTPD--GTREFLTLEVPLNDSGSAGLGVSVKGNRSK-----------------ESHADLGIFVKSIINGGAACKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRKSMS-TEGNKRGMIQLIVARRINKRLEGE--------------------------------SRGSPRGLERTLSPSPDDHERRISHSLY-GIEGLDDNLRPQASTNNRKMN---HYQLSPTVNMPQ----------------------------------------------------DDTVIIEDDRPHVLP-----IQLSDQSSSSSHDDMGFAVETP--PPPPWEPELPDSSS-----------SANAEG--QFQREGFGRQSMSEKRTKQYGDAGQLDIIKTR-----KSKSMDL----------------GSSTRDVGPSLGLKKSSSLESLQTAVAEVTLNGDMPFHRPRP-RIIRGRGCNESFRAAIDKSYDRPAANEDEEECMDTLEEDTEGSSRSGRDSVSTVADLTPLPVTEQQLINGNQPE-NDKKKEKGGKDKKK---PEKEKGKTKKG-MLKGLGEMFRFGKYRKDERLDG-AKWKAEETHASEEETRRMKQEQERIQAKTREIRQRQARERDYAEIQDFSRSTLTSLPPEEPPYAGIGSLEHGGYHRIHTPPDSP---------YTQKQNGRNGHPS--TSDRLTPSNHDRIQRLRQEFQQVRQEETEPDDRHRSYSMEQPWSNCSSQSSSGRHSVSVEVQLQR--QEARDAFTHAQRQYSSLPRHPRKTPTPASESEWERTGPSVDAFQAAKDSGRYSSYQGPRSVPRTVPRHGCRNGFSAAPGSSSSSVGSGYNARVLLEAQELLRQEQRRREQEMKGRGPSIR----------VDYECQDSKGPQRQDVPPSPSQVVRLSRIHTPEKTRPFLS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KHR3-1", "uniprot_id": "Q0KHR3_DROME", "id": "Q0KHR3-1", "name": "", "aln": "MFDVPPKCPALANKLGGLFGWRHTYKVAAKQEGIPHGQLHKSYSLTLPKRPPSPSTYSCVKPDSWVTVTHLQTQSG-ILDPDDCVRDVADDREQILAHFDDPGPDPGVPQGGGDGASGSSSVGTGSPDIFRDPTNTEAPTCPRDLSTPHIEVTSTTSGPMAGLGVGLMVRRSSDPNLLASLKAEGSN-------------KRWSAAAPHYAGGDSPERLFLDKAGG---------QLSPQWEEDDDPSHQLKEQLLHQQQPHAANGGSSSGNHQPFARSGRLSMQFLGDGNGYKWMEAAEKLQNQPPAQQTYQQGSHHAGHGQ-NGAYSSKSLPRESKRKEPLGQAYESIREKDGEMLLIIN-----EYGSPLGLTALPDKEHGGGLLVQHVEPGSRAERGRLRRDDRILEINGIKLIGLTESQVQEQLRRALESSELRVR-----VLRGDRNRRQQRDSKVAEMVEVATVSPTRKPHAAPVGTSLQVANTRKLGRKIEIMLKKGPNGLGFSVTTRDNPAGGHCPIYIKNILPRGAAIEDGRLKPGDRLLEVDGTPMTGKTQTDVVAILRGMPAGATVRIVVSRQQELAEQADQPAEKSAGVAVAPSVAPPAVPAAAAPAPPIPVQKSSSARSLFTHQQQSQLNESQHFIDAGSESAASNDSLPPSSNSWHSREELTLHIPVHDTEKAGLGVSVKGKTCSNLNASGSSASSGSNGLMKHDGDLGIFVKNVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRAMVNTPGKHPGTITLLVGRKILRSASSSDILDHSNSHSHSHSNSSGGSNSNGSGNNNNSSSNASDNSGATVIYLSPEKREQRCNGGGGGGSAGNEMNRWSNPVLDRLTGGICSSNSAQPSSQQSHQQQPHPSQQQQQQRRLPAAPVCSSAALRNESYYMATNDNWSPAQMHLMTAHGNTALLIEDDAEPMSPTLPARPHDGQHCNTSSANPSQNLAVGNQGPPINTVPGTPSTSSNFDATYSSQLSLETNSGVEHFSRDALGRRSISEKHHAALDARETGTYQRNKKLREERERERRIQLTKSAVYGGSIESLTARIASANAQFSGYKHAKTASSIEQRETQQQLAAAEAEARDQLGDLGPSLGMKKSSSLESLQTMVQELQMSDEPRGHQALRAPRGRGREDSLRAAVVSEPDASKPRKTWLLEDGDHEGGFASQRNGPFQSSLNDGKHGCKSSRAKKPSILRGIGHMFRFGKNRKDGVVPVDNYAVNISPPTSVVSTATSPQLQQQQQQQLQQHQQQQQIPTAALAALERNGKPPAYQPPPPLPAPNGVGSNG---IHQNDIFNHRYQHYANYEDLHQQHQQHQISGGDSTTSISETLSESTLECMRQQVIRQRIKVEAESRRHQHYHSQRSARSQDVSMHSTSSGSQPGSLAQPQAQSNGVRPMSSYYEYETVQQQ-RVGSIKHSHSSSATSSSSSPINVPHWKAAAMNGYSPAS-------------------------LNSSARSRGPFVTQVTIREQSSGGIPAHLLQQHQQQ------------------QLQQQQPTYQTVQKMSGPSQYGSAAGSQPHASKV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .. .: :* *: . . : : . : *: * :*: .* *** ** : *****:::::* **: * : ****:* :* .** **::: . .*. .. . *: *.* .: * ******* * . *: .***::* . : :: : . .*.: : .:: .. * .:* . . . . :. .. :: :* .: .*:: :. ::*. . * .. . ::* ** * *:* . ::.: :: ** : . : : : : .: * . : : :: : : :: .. . :: : . .. . : * *:::*::: * ****.:*****:*:** . ** .***:**********:*****.****:**:*. : *: * :**::**. .** ::* **: ::* . :: * ..::.: :.: :** **:.:*::*: .*********: .. : ..*******.:*:****.:*****:****::*** ** *: * :******::* * *:: * * *:*.*:* : . * .* . : :.:*:* . . * * : . :. . . . .*: : .: : :::**** : * : .::..:** : . . .. * . *.*:.:**:*:***: . :.: :.:. : . . * *::.: .*:: :: * . . * : : . * ::* :: : .*: ::*. . ... :. . .. . : :: ::: :.. : .. ::** :*:*:*.****** *** : .. :* . : *:: * : :: :::* : : . . : : : * :: :. . :. . ... :: :**:. : : . . *:: * ::. . * . . * *. : :*.:: :: * . *... . .. . . ..*. . . . .:* : :* :*::. : : :* . : .:: .: :. :*. * ", "identical_positions": 247, "similar_positions": 404, "identity": "15.43%" }, { "cls_id": "homologset.agr.RGD:620375", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70489-1", "uniprot_id": "PPT2_RAT", "id": "O70489-1", "name": "Lysosomal thioesterase PPT2", "aln": "MPGLWRQRLPSAWALLLLPFLPLLLPAAPAPHRGSYKPVIVVHGLFDSSYSFRHLLDYINETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMEKAPEGVHLICYSQGGLVCRALLSVMDEHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWHDPHHDDLYLNASSFLALINGERDHPNATAWRKNFLRVGRLVLIGGPDDGVITPWQSSFFGFYDANETVLEMEEQPVYLRDSFGLKTLLARGAIVRCPMAGVSHTTWHSNRTLYDA-------CIEPWLS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35448-1", "uniprot_id": "PPT2_MOUSE", "id": "O35448-1", "name": "Lysosomal thioesterase PPT2", "aln": "MPGLWRQRLPSAWALLLLPFLPLLMPAAPAAHRGSYKPVIVVHGLFDSSYSFRHLLDYINETHTGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMEKAPEGVHLICYSQGGLVCRALLSVMDNHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRVCYSPWGQEFSICNYWHDPHHDDLYLNASSFLALINGERDHPNATAWRKNFLRVGRLVLIGGPDDGVITPWQSSFFGFYDANETVLEMEEQPVYLRDSFGLKTLLARGAIVRCPMAGISHTTWHSNRTLYDT-------CIEPWLS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMR5-1", "uniprot_id": "PPT2_HUMAN", "id": "Q9UMR5-1", "name": "Lysosomal thioesterase PPT2", "aln": "MLGLCGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYINETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRALLSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPWQSSFFGFYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYET-------CIEPWLS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HX37-1", "uniprot_id": "A0AC58HX37_DANRE", "id": "A0AC58HX37-1", "name": "palmitoyl-CoA hydrolase", "aln": "MKGACVWTLVSVCVFCVC---------------VAYKPVIVVHGLFDSSADFVHLHRFINLSHPGTNVTVLDLFDRSASLQPLWKQVEGFTEAIYPIMQNAADGVHLICYSQGGLVCRGILSTLPDHNVHSFISLSAPQAGQYGDTDYLKYLFPQFVKSNLFHVCYTAVGQKISICNYWNDPHHRDMYINSSDYLALLNNERPNPNSTAWKQNFLRIKKLVLIGGPDDGVITPWQSSQFGFYDDNETVVEMKNQKVFLMDLFGLKTLSARGDLALCSVEGVAHIFWHSNETYFSALHQNRHFCYSDSASMENP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1RD68-1", "uniprot_id": "F1RD68_DANRE", "id": "F1RD68-1", "name": "palmitoyl-CoA hydrolase", "aln": "MTDSSRPCVFIWAVLLLLP-----------TVIMAYRPVILVHGLFGGPEQMEMLKKYIKRSHPGTSVTAISLYDDNASSKPMWEQVDGFREAIRPIMDRAKDGVHLICYSQGGLICRGVLATLPHHNVHSVIFLSSPLAGQYGDSNYISKFFPSFVKSTLYNACYTTRGQQISSCSYWKDPHQIEKYLKYSVFLAPLNGEVETVHTQAWRKNFLRIKTMVLLGGPDDGTIKPWQSSMFGFYNRNEKVIDMEHQDYYISDSFGLKTLNRRKAIVKCIIPDVHHDAWPTDYKIYKK-------CIEKWLT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKH6-1", "uniprot_id": "PPT2_DROME", "id": "Q9VKH6-1", "name": "Lysosomal thioesterase PPT2 homolog", "aln": "----MRLRLQVLVALLTCS---------SISVSLAYKPVVILHGILSGAESMASLVREIEEFHPGTIVYNCDKFNGWYSLENAWRQVDQVRDYLNEVGKLHPEGIIVLGYSQGGLLARAAIQSLPEHNVKTFISLSSPQAGQYG-TSFLHLIFPDLAAKTAFELFYSRVGQHTSVGGYWNDPQRQDLYLKYSEFLPLINNEKKTSNSTSFKMGMVRLNKLVMIGGPNDDVITPWQSSHFGYFDENMDVIPFIRRPIFTSDSIGIRTLQEAGKLIIVVKPHVHHLAWHTRRDVIHE-------VIFPYLD----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: :*:**:::**::... .: * *: *.** * . :: * . *.**: . : : : :*: :: ******:.*. : : .***.:.* **:* **** :.:: :** .. :. *: **. * .**:**:: : *:: * :*. :*.* :: :: .::*: :*::***:*..*.***** **::: * *: : .: : * :*::** : : * * : ", "identical_positions": 71, "similar_positions": 92, "identity": "22.68%" }, { "cls_id": "homologset.agr.RGD:620376", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CY27-1", "uniprot_id": "TECR_MOUSE", "id": "Q9CY27-1", "name": "Very-long-chain enoyl-CoA reductase", "aln": "MKHYEVEIRDAKTREKLCFLDKVEPQATISEIKTLFTKTHPQWYPA-RQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFR---VPFIYGRKYDFTSSRHTVVHLACMCHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYIN---------HPLYTPPTYGVQQVKLALAVFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAILTQC-VPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64232-1", "uniprot_id": "TECR_RAT", "id": "Q64232-1", "name": "Very-long-chain enoyl-CoA reductase", "aln": "MKHYEVEIRDAKTREKLCFLDKVEPQATISEIKTLFTKTHPQWYPA-RQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFR---VPFIYGRKYDFTSSRHTVVHLACMCHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYIN---------HPLYTPPTYGVQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQC-VPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NZ01-1", "uniprot_id": "TECR_HUMAN", "id": "Q9NZ01-1", "name": "Very-long-chain enoyl-CoA reductase", "aln": "MKHYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQWYPA-RQSLRLDPKGKSLKDEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFR---VPFIYGHKYDFTSSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYIN---------HPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLFLLVSCPNYTYEVGSWIGFAIMTQC-LPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLRMPIIPFLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZL3-1", "uniprot_id": "Q9VZL3_DROME", "id": "Q9VZL3-1", "name": "very-long-chain enoyl-CoA reductase", "aln": "---MELEILNAKNSKPYGKVKVPSGATPIGDLRALIHKTLKQTPHANRQSLRLELKGKSLKDTDTLESLSLRSGDKIYVKDLGPQIGWKTVFLAEYAGPLIVYLIFYFR---PELVYGKAASLPIS--LTTHIAAGCYTVHYVKRLLETIFVHRFSHATMPLRNLFKNCTYYWGFTAYVSYHVN---------HPQFTSP--CMCTVWGALGAFALCELGNFSVHIALRNLRPPGTKVRKIPVADGNPLTKLFDLVSCPNYTYEIGAWVSFSVLTSC-LAAYLFAFAGAFQMTIWALAKHRNYKKEFKDYPRQRRSIFPFVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99190-1", "uniprot_id": "TECR_YEAST", "id": "Q99190-1", "name": "Very-long-chain enoyl-CoA reductase", "aln": "---MPITIKSRSKGLRDTEIDLSKKPTLDDVLKKISANNHNISKYRIRLTYKKESKQVPVISESFFQEEADDS-MEFFIKDLGPQISWRLVFFCEYLGPVLVHSLFYYLSTIPTVVDRWHSASSDYNPFLNRVAYFLILGHYGKRLFETLFVHQFSLATMPIFNLFKNCFHYWVLSGLISFGYFGYGFPFGNAKLFKYYSYLKLDDLSTLIGLFVLSELWNFYCHIKLRLWGDYQKKHGNAKIRVP-LNQGIFNLFVAPNYTFEVWSWIWFTFVFKFNLFAVLFLTVSTAQMYAWAQKKN-------KKYHTRRAFLIPFVF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . .. :. . : :: : :. * : : : * .: . . ::. . : ::.:***.**.* **: ** **:::: :**: .: . ::* ** ***:**:***:** .***: *:**** :** ::. ::: : . : :. *.:.:* ** *: ** .* : :* *. .****:*: :*: *:.: . : . ** .. ** ** *: :.* * ::**::", "identical_positions": 68, "similar_positions": 90, "identity": "21.12%" }, { "cls_id": "homologset.agr.RGD:620379", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56656-1", "uniprot_id": "CP239_MOUSE", "id": "P56656-1", "name": "Cytochrome P450 2C39", "aln": "MDLVTFLVLTLSSLILLSLWRQSCGRGSLPPGPTPFPIIGNFLQIDIKNVSQS-----LTNFSKAYG-PVFTLYLGSRPTVVLHGYEAVKEALIDHGEEFSDRGSIPMVEKINN-GLGIVFSNGNRWKEIRRFTLTTLRNLGMGK--RNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAP------------CNVICSIIFQDRFDYKDKDFLMLMEKLNENVKILSSPWLQVCNNFPLLIDYCPG--SHHKVLKNVKYIRSYLLEKIKEHQESLDVTNP---RDFIDYYLIKQK-QANHIQQAEFSLENLACTINNLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVIGRHRS---PCMQDRNHMPYTDAMIHEVQRFINLVPNNIPRAVTCDIKFRNYLIPKGTTVVTSLTSVLHDSKEFPNPELFDPGHFLDANGN-FKKSDHFMPFSAGKRVCAGEGLARMELFLFLTTILQNFKLKSLVHPKDIDMIPFVNGLIALPPHYQVCIIPR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56655-1", "uniprot_id": "CP238_MOUSE", "id": "P56655-1", "name": "Cytochrome P450 2C38", "aln": "MDLVTFLVLTLSSLILLSLWRQRSRRGRLPPGPTPFPIIGNFLQIDVKNFNQS-----LTNFSKTYG-PVFTLYLGSRPIVVLHGYEAVKEALIDHGEEFSGRENIPMSEKINN-GLGITFSNGNSWKETRRFTLMTLRNLGMGK--RNIEDRVREEAQCLVEELRKTKGSPCDPTFILSCAP------------CNVICSIIFQDRFDYKDKDFLMLMKKLNENVKILSSPWLQVCNNFPLLIDYCPG--SHHKVLKNFKYIRSYLLEKVKEHQESLDVTNP---RDFIDYFLIKQK-QANHIEQAEYSLENLVCTINNLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVVGRHRS---PCMQDRSRMPYTDAMIHEVQRFINLVPNNLPHAVTCDIKFRNYIIPKGTTVVTSLTSVLHDSKEFPNPEMFDPGHFLDANGN-FKKSDYFMTFSAGKRVCAGEGLARMELFLILTTILQNFKLKSLVHPKDIDMIPFVNGLITLPPHYQLCFIPL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05179-1", "uniprot_id": "CP2C7_RAT", "id": "P05179-1", "name": "Cytochrome P450 2C7", "aln": "MDLVTFLVLTLSSLILLSLWRQSSRRRKLPPGPTPLPIIGNFLQIDVKNISQS-----LTKFSKTYG-PVFTLYLGSQPTVILHGYEAIKEALIDNGEKFSGRGSYPMNENVTK-GFGIVFSNGNRWKEMRRFTIMNFRNLGIGK--RNIEDRVQEEAQCLVEELRKTKGSPCDPSLILNCAP------------CNVICSITFQNHFDYKDKEMLTFMEKVNENLKIMSSPWMQVCNSFPSLIDYFPG--THHKIAKNINYMKSYLLKKIEEHQESLDVTNP---RDFVDYYLIKQK-QANNIEQSEYSHENLTCSIMDLIGAGTETMSTTLRYALLLLMKYPHVTAKVQEEIDRVIGRHRS---PCMQDRKHMPYTDAMIHEVQRFINFVPTNLPHAVTCDIKFRNYLIPKGTKVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGN-FKKSDYFLPFSAGKRACVGEGLARMQLFLFLTTILQNFNLKSLVHPKDIDTMPVLNGFASLPPTYQLCFIPS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64458-1", "uniprot_id": "CP2CT_MOUSE", "id": "Q64458-1", "name": "Cytochrome P450 2C29", "aln": "MDLVVFLALTLSCLILLSLWRQSSGRGKLPPGPTPLPIIGNFLQIDVKNISQS-----FTNFSKAYG-PVFTLYLGSKPTVILHGYEAVKEALIDRGEEFAGRGSFPMAEKIIK-GFGVVFSNGNRWKEMRRFTLMTLRNLGMGK--RNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAP------------CNVICSIIFQNRFDYKDKEFLILMDKINENVKILSSPWLQVCNSFPSLIDYCPG--SHHKIVKNFNYLKSYLLEKIKEHKESLDVTNP---RDFIDYYLIKQK-QVNHIEQSEFSLENLASTINDLFGAGTETTSTTLRYALLLLLKYPDVTAKVQEEIDRVVGRHRS---PCMQDRSHMPYTDAMIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPKGTTVITSLSSVLHDSKEFPNPEMFDPGHFLNGNGN-FKKSDYFMPFSTGKRICAGEGLARMELFLILTTILQNFKLKSLVHPKEIDITPVMNGFASLPPPYQLCFIPL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10632-1", "uniprot_id": "CP2C8_HUMAN", "id": "P10632-1", "name": "Cytochrome P450 2C8", "aln": "MEPFVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKS-----FTNFSKVYG-PVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITK-GLGIISSNGKRWKEIRRFSLTTLRNFGMGK--RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAP------------CNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPG--THNKVLKNVALTRSYIREKVKEHQASLDVNNP---RDFIDCFLIKME-QEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRS---PCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN-FKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "MSALIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGT-RKGITCTDGQLWYEHRHFAMKQMRNVGYGR--SQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSV------------LNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGK-CFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAG--ESPSMVLLPGITLTPKPYKVQFVKRT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG17-1", "uniprot_id": "CP304_DROME", "id": "Q9VG17-1", "name": "Probable cytochrome P450 304a1", "aln": "MITETLLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYLHK--AALTLSRWYKSDIIGLHVGPFPVAVVHSADGVREILNNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPLLFNPFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEEGVE---RNFMDVYIAEMR----RGPGYGFNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRL---PNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLIISPPDFWLQLQDRH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .* :: * :**** .* :*. * : :: : :. : .* .: . : ::* :. . . *: :* * * *:* : :*:.* *: .:* :. : . :: :.. * : . *. : . : :: * : . . . : :* : . * :: : : :: . :.:: . ::: :: : . :. :* : :: .. : . : : * * * :: .:: :. * :. *. : : :* : * * : * *: . :: * ***.: :: * :. * . : :* * * :*:: *: * : :.*. *:* * *: :** :* . . : *:*.. *: * : : : ", "identical_positions": 62, "similar_positions": 141, "identity": "11.88%" }, { "cls_id": "homologset.agr.RGD:62038", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28023-1", "uniprot_id": "DCTN1_RAT", "id": "P28023-1", "name": "Dynactin subunit 1", "aln": "MAQSKRHMYNRTPSG--SRMSTEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDG---------ADTTSPETPDSSASKILKREGADAAAKTSKLRGLK-PKKAPTARKTTTRRPKPTRPASTGVAGPSSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPT------------------PALTSPG-----AAPPLPSPSKEEEGLRDQVRDLEEKLETLRLKRSEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEA-KEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS-----------DGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPP-----PETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLA-EQPEESTMQLADHIKFTQSALDCMSVEVGRLRAFLQGGQEATDIALLLRDLETSCSDIRQFCKKIRRRMPGTDAPGIPAALAFGSQVSDTLLD--CRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGSPSSSPYECLRQSCSILISTMNKLATAMQEGEYDAERPPSKPP----------PVEPWPAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQTLLRKKEKEFEETMDALQADIDQLEAEKTELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEQQRGGTPGQAPGALPGPGPVKDSPLLLQQISAMRLHISQLQHENSILRGAQMKASLAALPPLHVAKFSLPPHEGPGGNLLSGALYRKTSQLLEKLNQLSTYTHVVDITRSSPACKSPSAQLMEQVAQLKSLSDTIEKLKDEVLKETVTQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGLGQRHRLVLTQEQLHQLHGRLIS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08788-1", "uniprot_id": "DCTN1_MOUSE", "id": "O08788-1", "name": "Dynactin subunit 1", "aln": "MAQSRRHMSSRTPSG--SRMSTEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDG---------ADTTSPETPDSSASKVLKREGADAAAKTSKLRGLK-PKKAPTARKTTTRRPKPTRPASTGVAGPSSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPT------------------PALTSPG-----AAPPLPSPSKEEEGLRAQVRDLEEKLETLRLKRSEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS-----------DGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPP-----PETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLA-EQPEDSTMQLADHIKFTQSALDCMGVEVGRLRAFLQGGQEATDIALLLRDLETSCSDTRQFCKKIRRRMPGTDAPGIPAALAFGSQVSDTLLD--CRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGSPSSSPYECLRQSCTILISTMNKLATAMQEGEYDAERPPSKPP----------PVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLDETQTLLRKKEKDFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEPQRGGAPGQAPGALPGPGLVKDSPLLLQQISAMRLHISQLQHENSILRGAQMKASLAALPPLHVAKLSLPPHEGPGGNLVAGALYRKTSQLLEKLNQLSTHTHVVDITRSSPAAKSPSAQLMEQVAQLKSLSDTIEKLKDEVLKETVTQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGLGQRHRLVLTQEQLHQLHSRLIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14203-1", "uniprot_id": "DCTN1_HUMAN", "id": "Q14203-1", "name": "Dynactin subunit 1", "aln": "MAQSKRHVYSRTPSG--SRMSAEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDG---------ADTTSPETPDSSASKVLKREGTDTTAKTSKLRGLK-PKKAPTARKTTTRRPKPTRPASTGVAGASSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPT------------------PVLTSPG-----AVPPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS-----------DGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPP-----PETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEKFELSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLA-EQPEDCTMQLADHIKFTQSALDCMSVEVGRLRAFLQGGQEATDIALLLRDLETSCSDIRQFCKKIRRRMPGTDAPGIPAALAFGPQVSDTLLD--CRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLLVAALEELAFKASEQIYGTPSSSPYECLRQSCNILISTMNKLATAMQEGEYDAERPPSKPP----------PVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEQQRGAIPGQAPGSVPGPGLVKDSPLLLQQISAMRLHISQLQHENSILKGAQMKASLASLPPLHVAKLS---HEGPGSELPAGALYRKTSQLLETLNQLSTHTHVVDITRTSPAAKSPSAQLMEQVAQLKSLSDTVEKLKDEVLKETVSQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGFGQRHRLVLTQEQLHQLHSRLIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QFT7-1", "uniprot_id": "A0A8M9QFT7_DANRE", "id": "A0A8M9QFT7-1", "name": "Dynactin subunit 1", "aln": "MSQMKRYTYSRTTSSGSSRMSSDGGGRPVKVGSLVEVIGKGHRGTVAYIGNTLFASGKWVGVILDEPKGKNDGTVQGKRYFLCQENHGIFVRQSQIQLVEDG---------ADTTSPETPEALTSKMLKREIIEG-LKSNKVRGTK-PKKAPTTRKTTTRRPKQTR------AGVGVKVG-SGSASAGEMSSSEPSTPAQTPLAAPVIPS------------------PVGALPSP----GAPPIPGPSKEEESLRALVKDLEEKLETLKMKRTEDKAKLKELEKHKIQLEQLQEWKSKMQEQQNELQKQLKEAKREAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQLEADALKERVDELTMDLEILKHEIEEKGS-----------DGAASSYHVKQLEEQNARLKEALVRMRDLSASEKQEHGKQQKLMEKKNFELDALRCHKEKLQEEMKMAEKTIDELKEQVDASLGAEEMVEMLTERNLDLEEKVRELRETVADLEAINEMNDELQENARETELELREQLDLGAAGVREAEKRVEAAQETVADYQQTIQKYRELTANLQEVNRELMSQQEANSEQQQQP------AEIFDFKIKFAETKAYAKAIEMELRKMEVIQANRQVSLLISFMPDSFLKHRGDHDCILALLLIPRLICKSELISKQAQEKFELTESCSQKPGMRGAVGERLSFAAGLIYSLTLLQAALHKYEHALSQCSVDVYKRVGSLYSELSVHERSLDFLIDLLYKDLLDETVNVEPLTKAIKYYQHLYSIHLA-EQPEDCTMQLADHIRFTQSALDCMAVEVGRLRAFIQTGQDEEAFCVLLKDLDTSCSDIRQFCKKIRRRMPGTDAPGIPAALSFGPQVCEALAD--SRRQLAWVNAVLQEVAAAAAQLIAPLSEHEGLPAVKLEDMAFKAAEQIYGSQGINAQECLRQSCSVVIATMNKMATAMQEGEYDSDRPQTGIS----------PVEVRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSASKDADERVEKIQAILDETDSLLKKKEKEFEETMDALQADIDQLESEKVELKHRISSQSKMTIESLRGSQASGIASIVTCGITAEEQKGVCAAAG-------LQVIDSPLLTQQIEAQRLSIKHLKNENNRLKAERMRAQLASLPPLNVPKLG--WREGCRPEVLSSALYRKTDQLLDTLLQMSANVKVVDITGRSPVS--PSAQLLEQTARLQSLNDTLDRLKDEVAEHVVTHRPGAQVSSDFATFPCTSFVKAKEEKRGDAVLVGRVMMPCARGQEQVHRLVLSQTQIHRVHRLLQT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58FY45-1", "uniprot_id": "A0AC58FY45_DANRE", "id": "A0AC58FY45-1", "name": "Dynactin subunit 1", "aln": "-------------------MSSDGGGRPVKVGSVVEVIGKGQRGTVAYIGATLFASGKWVGVILDEAKGKNDGTVQGKRYFTCEENHGIFVRQSQIQLMDDGG--------SSATSPETPDSGVAKLLKKEIQETPKTAKQTPAVKKPPVRRSTKWSTPGRLSTSSSLPSLIMTGRPSVG-GSALSESVLAESESSSSTQMSLAAPVVPQ------------------PSTASTP------APATP--SKEEESLRAQLKDLEEKLETLRMKRSEDKAKLKEMEKYKIQLEQLQEWRSKMQEQQNDLQKQLKEAKKEAREALEAKDRYMEEMADTADAIEMATLDKEMAEERAESLQQETESLKEKLEELTMDMEILKHEIEEKGS-----------DGAASSYHVKQLEEQNARLKEALVRMRDLSSSEKQEHVKLQKQMEKKNSELETLRSQKEKLQEEMKLAEDTIDELKEQVDAALGAEEMVETLTERNLDLEEKVRELRETVSDLESINEMNDELQENARETELELREQLDLAGARVREAQKRVEAAQETLADYQQTINKYRELTTHLQEVNRELTNQQSSSAEQLQQPA-----AELFDFKIKFAETKAYAKAIEMELRKMEVSQANRQVSLLTSFMPESFLRHGGDHDCILVLLLIPRLICKAELISKQAQEKFDLTGGSLERAGLRGAAGEQLSFASGLVYSLTLLQATLHKYELALSVCGVDVYKRMGMLYSEMCVHERSLDFLIDLLHKDQLDETVQVEPLTKAIKYYQHLYSVHLC-DQPEDCTVQLADHIKFTQSALDCMGSEVGRLRAFLQAGQEGAELCVLLKDLDTSCGDIRQFCKKIRRRMPGTDAPGIPAALRFSEQVSEALAD--SRKQLARVVAVLQEVSAAGAQMMAPLQEQEGLSAVKIEDVAFKAVEQVYGTQGLNPYECLRQSCSAVIATMNKMATAMQEGEYDSERPQRPPP----------PVETRAAAVRAEMTDAEGLGNKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDTSTKDADERVEKIQTKLDEALNTLKKKEKEFEETMDALQADIDQLESEKAELKQRISSQS-RATEGLRGQPASGIASIVTGNVAGGMLSAPAGVSG------VVQVVDSPLLKQQIDVQRIAIKQLKSENYRLKAERMRAQLSSLPPLQVPNMK---SVMMKENTAAGALQRKTDVLLHNLMKMSAGLKVVDITGKTTAS--ASAQLLEQTAKMKSLSDALDKLQAEVSQHVVSQQPGASVPSDFATFPTATFVKAQQEQQSGCVLVSKLMIPCARGKEQKHTLVLSQQQLQRVHHLLMT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13496-1", "uniprot_id": "DCTN1_DROME", "id": "P13496-1", "name": "Dynactin subunit 1", "aln": "-----------------------MSEKNLKVGARVELTGKDLLGTVAYVGMTSFAVGKWVGVVLDEPKGKNSGSIKGQQYFQCDENCGMFVRPTQLRLLEAAPGSRRSIEDVSGATPTAAQPTKARLSSSRTSLSSSRQSLLGSRTQLTTSLSERTASSSSIGPRKSLAPQNSKDKESPSTSLAEGAPAASGGNGAASHASSKRASFVETGFLEILKPQFTPSQPLRSPSFTMPSNSGAEDKVALLEAQKTSAELQAQLADLTEKLETLKQRRNEDKERLREFDKMKIQFEQLQEFRTKIMGAQASLQKELLRAKQEAKDAIEAKEQHAQEMADLADNVEMITLDKEMAEEKADTLQLELESSKERIEELEVDLELLRSEMQNKAESAIGNISGGGDSPGLSTYEFKQLEQQNIRLKETLVRLRDLSAHDKHDIQKLSKELEMKRSEVTELERTKEKLSAKIDELEAIVADLQEQVDAALGAEEMVEQLAEKKMELEDKVKLLEEEIAQLEALEEVHEQLVESNHELELDLREELDLANGAKKEVLRERDAAIETIYDRDQTIVKFRELVQKLNDQLTELRDRNSSNEKESLQDPSLKMVTETIDYKQMFAESKAYTRAIDVQLRQIELSQANEHVQMLTAFMPESFMSRGGDHDSILVILLISRIVFKCDIVVSQTRERFPPVDAITREAVTQGHAVQQYAFKCRLLHYVHSLQCALHQILYGLNSCQPDTLLRAGSSLPEMVAQEKIVDGIIELLKSNQLDENSTTDNIEKCVAFFNAMNSVLLAGEQLLNEIQMIRDCVASLGAACESILSDTAIAKVIIQEAGATSDSVLLIQFLNENMESVRQQVKLIKRRLPSDQHVIKSGLSQHKVEAMRGLAQNISRIMSAMHQATKQSLAAIVSTIESDNAAEHTLPQEKYWALLTASCERIYEQDDRGPTQNFKTLLAQANSDLQLIAQHLLDKEYDIISAANNASNQQKSGAHSTPITQRAQLIKKQLEQKNVLAATLENREADVKQLKVAAKMKQNELSEMQIRKDLAEKKLSVLQNEYEHAVDKWKQKYEETSLQLQLKEKEFEETMDHLQSDIDALESEKSDLRDKLKLNSTTGKVQPGSESHSPHNISLSGNTSTAPGISNVSYSAP--------AGTAPVVAEEVELLKNAFNQERNQRLRLQAQDMRAKLSQFEPLHVPQPQ-----DQRITALESELTRMKHAWVLSLLQVRSQDSVNSGTRIDAVALQRRNQPVPLKG---EISSKASQLASDILTEYLQRKPHRATHGQFASFPTVDVKRVLQI-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ::**: **: **. *****:* * ** ******:***.****.*:::*::** *:*. *:*** :*:::.: . . ::* :.:. ::: . . . . . : : ::. . . . : . : .: ::. . *..: * : . . .* . *: : ** ******: :* *** :*:*::* ***:**:**:::*: * .**:.* .* :**::*:***::: :**** ** :** *********:*::** * :: **:::** *:*:*: *:::*.. . . *:*..****:** ***::***:****: :*:: * .* :* *. *: :. :*:*. ::. * : :*:*****:******** *::::::**:**: *.* :.:**:::*::::* *. :* **:***:**:. . :*. :. :** **: * :*** *:*:*. :*:: ** .::.:. :. * .* :*:* ***:**:::**:::**::*: ***.::.:* :***:**: ****.:*.:**:.*:: *.::: .*::*:* ... :* . :: :* . *:: : **.:**: .*. * *. : * .*: .:*: :* :*:** .: ***. .: : *.: ::: : *: *. :* : : * : :* :.: :.. :.::* . :*:: *: . . ** * *:**:*. : .. . :. * : .* : *. *.::* : : : .. * : : *::* . .. : :: : :: :* : : *** . . *: . :: :: : : *. .**:**: :*:** : *:* :**** ::* .* ****. :: :. ::* : :*: *: ***:****** **:*** **:** :*:.::. :* . * :: . . . :*:: :::. : :.: : :. *:. *:*.*: : **:*.: . * * . : .* :: : * . * ... * : . .:.. .:* :: . : ::* . :**:** . :. : ", "identical_positions": 332, "similar_positions": 426, "identity": "24.68%" }, { "cls_id": "homologset.agr.RGD:620380", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920G2-1", "uniprot_id": "NHRF2_RAT", "id": "Q920G2-1", "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF2", "aln": "MAAPESLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVHRIKAVEGQTQLLVVDKETDEELCRRQLTCTEEMAHRGLPPAHNPWEPKPDWACSGSLGSDTGHKDVNGPPRELRPRLCHLRRGPQGYGFNLHSDKSRPGQYIRSVDPGSPASLSGLRAQDRLIEVNGQNVEGLRHAEVVARIKAQEDEARLLVVDPETDEHFKRLRVVPTEDHVEGPLPSPVTNGTSLAQLNGGSVCSSRSDLPGSEKDNEDGSAWKRDPFQESGLHLSPTAAEAKEKARATRVNKRAPQMDWNRKREIFSNF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JHL1-1", "uniprot_id": "NHRF2_MOUSE", "id": "Q9JHL1-1", "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF2", "aln": "MAAPESLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTQLLVVDKETDEELCRRQLTCTEEMAHRGLPPAHNPWEPKPDWACSGSLGSDTGQKDVNGPPRELRPRLCHLRRGPQGYGFNLHSDKSRPGQYIRSVDPGSPASHSGLRAQDRLIEVNGQNVEGLRHAEVVARIKAQEDEARLLVVDPETDEHFKRLRVVPTEEHVEGPLPSPVTNGTSPAQLNGGSVCSSRSDLPGSEKDNEDGSTWKRDPFQESGLHLSPTAAEAKEKARATRVNKRAPQMDWNRKREIFSNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15599-1", "uniprot_id": "NHRF2_HUMAN", "id": "Q15599-1", "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF2", "aln": "MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.*******************************************************************:*********:*****:****** ***********:*******:********* :** .*::*:***.** ***********:*****************************: *************************** ***:**********************.***:*************** *******.**********:**.****:**:*********************** *********************", "identical_positions": 307, "similar_positions": 22, "identity": "91.1%" }, { "cls_id": "homologset.agr.RGD:620381", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19639-1", "uniprot_id": "GSTM3_MOUSE", "id": "P19639-1", "name": "Glutathione S-transferase Mu 3", "aln": "MPMTLGYWNTRGLTHSIRLLLEYTDSSYEEKRYVMGDAPNFDRSQWLSEKFNLGLDFPNLPYLIDGSHKVTQSNAILRYLGRKHNLCGETEEERIRVDTLENQVMDTRIQLMIVCCSPDFEKQKPEFLKAIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYRMFEPKCLDAFPNLRDFLARFEGLKKISAYMKSSRFLPRPVFTKIAQWGTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVQ8-1", "uniprot_id": "D3ZVQ8_RAT", "id": "D3ZVQ8-1", "name": "Glutathione S-transferase", "aln": "MAMILGYWNVRGLTHPIRLLLEYTDSNYEEKRYVMGDAPNFDRSQWLSEKFNLGLDIPNLPYLIDGSHKVTQSNAILRYLGRKHNLCGETEEERIRVDTLENQVMDTRIHLMIVCCSPDFEKQKPEFLKSIPEKMKIYSEFLGKRPWFAGDKVTYVDFLAYDILDQYRMFEPECLDAFPNLKDFLARFEGLKKISAYMKSSSFLPRPVFTKIAQWGTD", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* *****.*****.**********.*****************************:****************************************************:*******************:******:***********************************:********:******************* ****************", "identical_positions": 206, "similar_positions": 10, "identity": "94.5%" }, { "cls_id": "homologset.agr.RGD:620382", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35820-1", "uniprot_id": "DNPH1_RAT", "id": "O35820-1", "name": "5-hydroxymethyl-dUMP N-hydrolase", "aln": "MAAS-----------GEQAPCSVYFCGSIRGGREDQALYARIVSRLRRYGKVLTEHVADAELEPLGEEAAGGDQFIHEQDLNWLQQADVVVAEVTQPSLGVGYELGRAVALGKPILCLFRPQSGRVLSAMIRGAADGSRFQVWDYAEGEVETMLDRYFEAYLPQKTASSSHPSA----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VJ3-1", "uniprot_id": "DNPH1_MOUSE", "id": "Q80VJ3-1", "name": "5-hydroxymethyl-dUMP N-hydrolase", "aln": "MAAS-----------GELVPCSVYFCGSIRGGREDQALYSRIVSRLRRYGKVLTEHVADAELEPRGEEAAGGDQFIHERDLAWLRQADVVVAEVTQPSLGVGYELGRAVALGKPILCLFRPQSGRVLSAMIRGAADGSRFQVWDYAEEEVETMLHRYFEAYLPQGTASSSNPSACLNPTVLEKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43598-1", "uniprot_id": "DNPH1_HUMAN", "id": "O43598-1", "name": "5-hydroxymethyl-dUMP N-hydrolase", "aln": "MAAAMVPGRSESWERGEPGRPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEEAAGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYELGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFEADPPGQVAASPDPTT----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A556-1", "uniprot_id": "DNPH1_DANRE", "id": "B8A556-1", "name": "5-hydroxymethyl-dUMP N-hydrolase", "aln": "--------------------MNIYFCGSIRGGRQDVVIYQTIVKKLQQYGNVLTEHVSYDSLSDKGEDKDG-DKAIHDRDVQWLTMSDVIVAEVTQPSLGVGYELGRAVAMNKRILCLFRPFSGKVLSAMIRGASAKPLFQVQDYKEDEVENILEEYFETLTKN--------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**********:* .:* **.:*:::*.******: .* **: * *: **::*: ** :**:********************:.* ******* **:*********: . *** ** * *** :*..***: ", "identical_positions": 86, "similar_positions": 28, "identity": "46.74%" }, { "cls_id": "homologset.agr.RGD:620383", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43852-1", "uniprot_id": "CALU_HUMAN", "id": "O43852-1", "name": "Calumenin", "aln": "---MDLRQFLMCLSLCTAFA----LSKPTEK-KDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKTFDQLTPEESKERLGKIVSKIDGDKDGFVTVDELKDWIKFAQKRWIYEDVERQWKGHDLNEDGLVSWEEYKNATYGYVLDDPDPDD------GFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDE-PEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35887-1", "uniprot_id": "CALU_MOUSE", "id": "O35887-1", "name": "Calumenin", "aln": "---MDLRQFLMCLSLCTAFA----LSKPTEK-KDRVHHEPQLSDKVHNDAQNFDYDHDAFLGAEEAKSFDQLTPEESKERLGKIVSKIDDDKDGFVTVDELKGWIKFAQKRWIHEDVERQWKGHDLNEDGLVSWEEYKNATYGYVLDDPDPDD------GFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNADE-PEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35783-1", "uniprot_id": "CALU_RAT", "id": "O35783-1", "name": "Calumenin", "aln": "---MDLRQFLMCLSLCTAFA----LSKPTEK-KDRVHHEPQLSDKVHNDAQNFDYDHDAFLGAEEAKSFGQLTPEESKEKLGMIVDKIDTDKDGFVTEGELKSRIKHAQKKYIYDNVENQWQEFDMNQDGLISWDEYRNVTYGTYLDDPDPDD------GFNYKPIMVRDERRFKMADQDGDLIATKEEFTAFLHPEEYDYMKDIVLQETMEDIDQNADGFIDLEEYIGDMYSHDGNADE-PQWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQDKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IQP3-1", "uniprot_id": "CALUA_DANRE", "id": "Q6IQP3-1", "name": "Calumenin-A", "aln": "---MEIRPLLMCFALCVVYA----TSKPTEK-KDRVHHDAPLSSKEHDDGTNFEYDHDAFLGEEEAKTFDDLTPEESKNRLGKIVEKIDADEDGFVTEAELKAWIKKAQKKYIYDNVERQWKDFDLNNDRMISWEEYKNVTYGTYLDDPEPDD------GYNYKQMMARDERRFKMADGNGDHIADKEEFTAFLHPEEYEHMKDIVVLETMEDIDKNGDGFIDLEEYIGDMYNHEDEMDE-PEWVATEREQFSEFRDKNKDGKMDREETMDWILPADYDHAEAEAKHLVYESDTNKDGKLTKEEILNKYDLFVGSQATDFGEALVRHDEF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7SXV9-1", "uniprot_id": "CALUB_DANRE", "id": "Q7SXV9-1", "name": "Calumenin-B", "aln": "---MEQWPLLFVVALCILQS----SSKPMEK-KDRVHHDAPLSNKDHDDEENFDYDHEAFLGQEEAKTFDQLTPEESKERLGKIVEKIDEDHDGFVTADEMKRWIKHAQRRWIYEDVDRQWQAHDLNSDSFVSWEEYKDATYGYILDEADPED------GFNYRQMMTRDERRFKMADQDGDLRANKEEFTAFLHPEEFDYMKDIVVLETMEDIDKNGDGLIDLNEYIGDMYSQNGDSSE-PEWVKTEREQFTEFRDKNKDGRMDKDETRDWILPADYDHAEAEAKHLLYESDADKDGRLTKQEIVDKYDLFVGSQATDFGDALVRHDEF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0H8-1", "uniprot_id": "Q9W0H8_DROME", "id": "Q9W0H8-1", "name": "Reticulocalbin-3", "aln": "MARTRIQMLLLVVALTAVISGASASSIPEELPHNPLEHDPLHPRHFDGGEHNAQFDHEAFLGPDESKKFDSLTPEESRRRLGVIVDRIDENKDGSVTLAELKNWIAYTQRRYIEEDVGRVWKQHNPDNNETISWDSYMQTVYG-FMDDLSPDEKEQEENGVSYKSLLKRDRYRWSVADQDLDDNLTKDEFTAFLHPEDHPSMKGVVLRETITDLDKDHDGKISVDEYIGDMYRSTGAEDEEPEWVANEREAFSTHRDLDKDGYLNEEEVKQWIAPHDFDHSEAEAKHLLFEADADHDDKLTKEEILDKYDVFVGSQATDFGEALARHDEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: .:* : * * * :: :.*:. . : ... . ::**:**** :*:*.*..******:.:** **.:** :.** ** *:* * :*:::* ::* . *: .: :.: :**:.* :..** :*: .*:: * .*: :: **. *:.:** : * *:*********:. **.:*: **: *:*:: ** *.::******* . .* *:** .*** * .** ::** ::.:*. :** * *:**:****:**::*:* ::*.:***:**::***:**********:**.*****", "identical_positions": 133, "similar_positions": 108, "identity": "40.3%" }, { "cls_id": "homologset.agr.RGD:620384", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31025-1", "uniprot_id": "LCN1_HUMAN", "id": "P31025-1", "name": "Lipocalin-1", "aln": "MKPLLLAVSLGLIAALQAHHLLASDEEIQDVSGTWYLKAMTVDREFPEMNL--ESVTPMTLTTLEGGNLEAKVTMLISGRCQEVKAVLEKTDEPGKYTADGGKHVAYIIRSHVKDHYIFYCEGELHGKPVRGVKLVGRDPKNNLEALEDFEKAAGARGLSTESILIPRQSETCSPGSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5VSP4-1", "uniprot_id": "LC1L1_HUMAN", "id": "Q5VSP4-1", "name": "Putative lipocalin 1-like protein 1", "aln": "MKPLLLAISLSLIAALQAHHLLASDEEIQDVSGTWYLKAMTVDRELPEMNL--ESVTPMTLTILEGGNLEAKATMLISGQCQEVKVILEKTDEPGKYTANRGKHVAYIIRSHMKDHYIFYCE--------------GRDPENNLEALEDFEKAAGARGLSTESILIPRQSETCSPGSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20289-1", "uniprot_id": "VEGP1_RAT", "id": "P20289-1", "name": "von Ebner gland protein 1", "aln": "MKALLLTFGLSLLAALQAQAFPTT-EENQDVSGTWYLKAAAWDKEIPDKKFGSVSVTPMKIKTLEGGNLQVKFTVLIAGRCKEMSTVLEKTDEPAKYTAYSGKQVLYIIPSSVEDHYIFYYEGKIHRHHFQIAKLVGRDPEINQEALEDFQSVVRAGGLNPDNIFIPKQSETCPLGSN", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.***:..*.*:*****: : :: ** *********** : *:*:*: :: *****.:. ******:.* *:**:*:*:*:..:*******.**** **:* *** * ::****** * ****: * ******:... * **..:.*:**:*****. **:", "identical_positions": 95, "similar_positions": 46, "identity": "53.37%" }, { "cls_id": "homologset.agr.RGD:620385", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZU7-4", "uniprot_id": "CABP1_HUMAN", "id": "Q9NZU7-4", "name": "Calcium-binding protein 1", "aln": "MGGGDGAAFKRPGDGARLQRVLGLGSRREPRSLPAGGPAPRRTAPPPPGHASAGPAAMSSHIAKSESKTSLLKAAAAAASGGSRAPRHGPARDPGLPSRRLPGSCPATPQSSGDPSSRRPLCRPAPREEGARGSQRVLPQAHCRPREALPAAASRPSPSSPLPPARGRDGEERGLSPALGLRGSLRARGRGDSVPAAASEADPFLHRLRPMLSSAFGQDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88751-1", "uniprot_id": "CABP1_RAT", "id": "O88751-1", "name": "Calcium-binding protein 1", "aln": "---------------------------------------------------------MSSHIAKSESKTSLLK--AAAASGGSRAPRHSSARDPGLRGRRLPGPCPDSPATCGDPSSRRPLCRPVPRDEGARGSRRGLPQAHCRPRETLP-------------PARGRDGEERGLAPALSLRGSLRSRGRGDPAPAGTPEADPFLHQLRPMLSSAFGQDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLK7-1", "uniprot_id": "CABP1_MOUSE", "id": "Q9JLK7-1", "name": "Calcium-binding protein 1", "aln": "-----------------------------------------------------------------------------------------------------MGNCVKSP--------LRNLSRKMRQEE--KTSYMAVQTS------------------------------EDGLADGGELHGPLMMLAQN--CAVMHNLLGPACIFLRKGFAENRQPDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :* * *.* ::* : * : : * **: . *:*.* .:. .. .* ** ::. ********************************************************************************************************************************************************", "identical_positions": 169, "similar_positions": 20, "identity": "45.68%" }, { "cls_id": "homologset.agr.RGD:620386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FGP3-1", "uniprot_id": "F7FGP3_RAT", "id": "F7FGP3-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MLVVLLTVVLLPLSSVQSSHEDHG------------------------------------------HQTQP-----LPP--HPDHGNQTQPRPPHPD---------------------IGNQTQPRPPHPDHGNQTQP---------RPPHPDQGNQTQPRPPH--------------------PDHGNQTQP-------------------------------RPPHPDQGNQTQP---------HPPHPDHGNQTQP-RP------PHPDQGNQTQPRPPQPGQGNHTHPRPPH--------------------PDHGNQTQP---------HPPHPDQGNQTQPRPPH---------PDHGNQTQP---------RPPHPDQGNQTQPRPPHPDH-------GNQTQPRPPHPDQGNQTQPRPPH--------------------PDQGNQTQPRPPHPDQGNQT-------QPRPPHPDQGNQTQP-RP---PHPDLGNQTQPRPPRPGQ---------------GNQTQPRPPRPG--------QGNQTQPRPPLPG--QGN--QNQHPHSPLPDHPPHPDYQRTPQQDGGNQLGSQPPPPAY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04118-1", "uniprot_id": "PRB3_HUMAN", "id": "Q04118-1", "name": "Basic salivary proline-rich protein 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MLLILLSVALLALSSAQSLNEDVS------------------------------------------QEESPSVISGKPEGRRPQGGNQPQRTPPPP------------------------GKPEGRPPQ--GGNQSQG---------PPPRPGK-----PEGPP--------------------PQGGNQSQG-------------------------------PPPRPGKPEGQPP---------QGGNQSQGPPPRPGKPE----GPPPQGGNQSQGPPPRPGK-----PEGPP--------------------PQGGNQSQG---------PPPRPGK-----PEGPP---------PQGGNQSQG---------PPPHPGK-----PEGPPPQG-------GNQSQGPPPRPGK-----PEGPP--------------------PQGGNQSQGPPPRPGKPEGP-------PPQGGNKPQGPPPRPGKPE-GPPPQGGNQSQGPPPRPGKPE-------GPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQ-RPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPPQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X2JBD0-1", "uniprot_id": "X2JBD0_DROME", "id": "X2JBD0-1", "name": "", "aln": "MTTNRSTRLLVLLVLTALVASHQAHAAAVGLKCGGKSAVCVGPLSYQQCVDDLTTGPVVPCALNTRCVTDGLEICVPVKSAAEAPTAAVAKMVTITDSPVVSESAPLVDSTNSGSGVEISTEGAPASAVPTKPSIPVETTQAPVETTQIPLETTQVAVETTQIPLETTQASGETTTAAIEETTTGSEAPLEPESTVPSDTTPVDSTLAPGWEGTYPTIEPNTPAEDPNAPAGTTLAPGEVDPNSPIDPNSPLDPNAPEESTNEPGLVDPTLPADTTTAPDSPVEGSSAAPGTPADVTTAAPGAPADGSSAAPGSPADGSSAAPGSPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPAEGSSAAPGAPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPAEGSSAAPGAPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPAEESSAAPGSPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPAEGSSAAPGAPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPAEGSSAAPGSPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPAEGSSAAPGSPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPAEGSSAAPGAPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGAPADVTTAAPGAPADGSSAAPGSPAEGSSAAPGAPADVTTAAPGAPADGSSAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPADVTTAAPGAPADGSSAAPGSPAEGSPPAGGSPAGSNVPAGGDPADSNVPAGGAPADSNVPAGGAPADSNVPAGGAPADSNVPAGGAPADANVPAGGAPADSNVPGGGAPADANVPAGGAPADSNVPAGGAPAGSNVPAGGAPADSNVPAGGAPADSNVPAGGAPAGSNVPAGSSPGSSVLGPNPPAGSVVPSIPVLPGGAGSWPWHPRPNIPIVPPTWRPLLPGQNGSGAPGSGLINGIVNPPQRPHPFWPNWQSWVNSWRPTKPVPSTEAPVQPQNPQQPQNPQQPGNSNPETAESVEQAAPVPPANVPASNENASVEDSNKASSEKSKDKPKSGEDQSKEQEQKKPSSEEKEKDSKEKNDKDSKEKKDNDSKDKKDKSKEEKDNESQKDNDGDDEPSSKEKKQYVKDLIKKLKKGDECDEDDVYPDVRDCRKYYRCEVKKSGKHKFAHLRCDKKERFDWLTQSCVPKDEARCLEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. :.*.:.*: * . * * *: * * .. * *..: * * . * * * *..: * * : . * .* . * * . . .: : * *.. * * * *..: * * . * * * *..: * * . * * : .: : * * . * * * *..: .* .. . . :* . * * . . *. :: .. ** .. . *. :*... .* * . . . . .. . .* . ", "identical_positions": 56, "similar_positions": 80, "identity": "3.61%" }, { "cls_id": "homologset.agr.RGD:620387", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYM2-1", "uniprot_id": "PARG_RAT", "id": "Q9QYM2-1", "name": "Poly(ADP-ribose) glycohydrolase", "aln": "MSAGPGCEPCTKRPRWGAAGTSAPTASDSRSFPGRQKRVLDPKDAPVQFRVPPSSSACVSGRAGPHRGSVTSFVFKQKPITTWMDTKGPKTAESE---SKENNNTRTDPMMSSVQKDNFYPHKVEKLGNVPQLNLDKSPTEKSTPYLNQQQTAGVCKWHSAGERAEQLSASEPSAVTQAPKQLSNANIDQSPPTDGHSDTDHEEDRDNQQFLTPVKLANAKQTVGDGQAR---SNCKCSASCQCGQDCAGCQREEADVIPESPLSDVGAEDIGTGSKNDNKLTGQESGLGDSPPFEKESEPESPMDVDNSKTSCQDSEADEEASPVFDEQDDQDDRSSQTANKLSSRQAREVDGDLRKRYLTKGSEIRLHFQFEGG-SNAGTSDLNAKPSGNSSSLNVDGRSSKQHGKRDSKITDHFVRIPKSEDKRKEQCEVRHQRAERKIPKYVPPNLPPDKKWLGTPIEEMRKMPRCGVRLPLLRPSASHTVTVRVDLLRAGEVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTALLNKFTRPQNLKDAILKYNVAYSKKWDFTALVDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQPIPLLKQKMNHSVTMSQEQIASLLANAFFCTFPRRN-AKMKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCYFRRVTEKK------PTGLVTFTRQS--LEDFPEWERCDKPL--TRLHVTYEGTIEGNGRGMLQVDFANRFVGGGVTGAGLVQEEIRFLINPELIVSRLFTEVLDHNECLIITGTEQYSEYTGYAETYRWARSHEDGSEKDDWQRCCTEIVAIDALHFRRYLDQFVPEKVRRELNKAYCGFLRPGVPPENLSAVATGNWGCGAFGGDARLKALIQLLAAAAAERDVVYFTFGDSELMRDIYSMHTFLTERKLNVGKVYRLLLRYYREECRDCS-----SPGPDTKLYPFIYHAAESSAETSDQPGQRTGT---------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88622-1", "uniprot_id": "PARG_MOUSE", "id": "O88622-1", "name": "Poly(ADP-ribose) glycohydrolase", "aln": "MSAGPGWEPCTKRPRWGAAGTSAPTASDSRSFPGRQRRVLDPKDAPVQFRVPPSSPACVSGRAGPHRGNATSFVFKQKTITTWMDTKGPKTAESE---SKENNNTRIDSMMSSVQKDNFYPHKVEKLENVPQLNLDKSPTEKSSQYLNQQQTASVCKWQNEGKHAEQLLASEPPAGTPLPKQLSNANIGQSPHTDDHSDTDHEEDRDNQQFLTPIKLANTKPTVGDGQAR---SNCKCSGSRQSVKDCTGCQQEEVDVLPESPLSDVGAEDIGTGPKNDNKLTGQESSLGDSPPFEKESEPESPMDVDNSKNSCQDSEADEETSPVFDEQDD---RSSQTANKLSSCQAREADGDLRKRYLTKGSEVRLHFQFEGE-NNAGTSDLNAKPSGNSSSLNVECRSSKQHGKRDSKITDHFMRISKSEDRRKEQCEVRHQRTERKIPKYIPPNLPPEKKWLGTPIEEMRKMPRCGIHLPSLRPSASHTVTVRVDLLRAGEVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTALLNKFTRPQNLKDAILKYNVAYSKKWDFTALVDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQPIPLLKQKMNHSVTMSQEQIASLLANAFFCTFPRRN-AKMKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCYFRRVTEKK------PTGLVTFTRQS--LEDFPEWERCEKPL--TRLHVTYEGTIEGNGRGMLQVDFANRFVGGGVTGAGLVQEEIRFLINPELIVSRLFTEVLDHNECLIITGTEQYSEYTGYAETYRWARSHEDGSEKDDWQRRCTEIVAIDALHFRRYLDQFVPEKVRRELNKAYCGFLRPGVPSENLSAVATGNWGCGAFGGDARLKALIQILAAAAAERDVVYFTFGDSELMRDIYSMHTFLTERKLDVGKVYKLLLRYYNEECRNCS-----TPGPDIKLYPFIYHAVESSAETTDMPGQKAGT---------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86W56-1", "uniprot_id": "PARG_HUMAN", "id": "Q86W56-1", "name": "Poly(ADP-ribose) glycohydrolase", "aln": "MNAGPGCEPCTKRPRWGAA-TTSPAASDARSFPSRQRRVLDPKDAHVQFRVPPSSPACVPGRAGQHRGSATSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEADEETSPGFDEQED--GSSSQTANKPSRFQARDADIEFRKRYSTKGGEVRLHFQFEGGESRTGMNDLNAKLPGNISSLNVECRNSKQHGKKDSKITDHFMRLPKAEDRRKEQWETKHQRTERKIPKYVPPHLSPDKKWLGTPIEEMRRMPRCGIRLPLLRPSANHTVTIRVDLLRAGEVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTALLNKFTRPQNLKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQPIPLLKQKMNHSITMSQEQIASLLANAFFCTFPRRN-AKMKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCYFRRVTEKK------PTGLVTFTRQS--LEDFPEWERCEKPL--TRLHVTYEGTIEENGQGMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNECLIITGTEQYSEYTGYAETYRWSRSHEDGSERDDWQRRCTEIVAIDALHFRRYLDQFVPEKMRRELNKAYCGFLRPGVSSENLSAVATGNWGCGAFGGDARLKALIQILAAAAAERDVVYFTFGDSELMRDIYSMHIFLTERKLTVGDVYKLLLRYYNEECRNCS-----TPGPDIKLYPFIYHAVESCAETADHSGQRTGT---------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O46043-1", "uniprot_id": "PARG_DROME", "id": "O46043-1", "name": "Poly(ADP-ribose) glycohydrolase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKSPDGGISEIETEEEPENLAN-------------------------------------------SLDDSWRGVSMEAIHRN-RQPFELENLPPVTAGNLHRVMYQLPIRETP-PRPYKSPGKWDSEHVRLPCAPESKYPRENPDGSTTIDFRWEMIERALLQPIKTCEELQAAIISYNTTYRDQWHFRALHQLLDEELDESETRVFFEDLLPRIIRLALRLPDLIQSPVPLLKHHKNASLSLSQQQISCLLANAFLCTFPRRNTLKRKSEYSTFPDINFNRLYQSTGPAVLEKLKCIMHYFRRVCPTERDASNVPTGVVTFVRRSGLPEHLIDWSQSAAPLGDVPLHVDAEGTIEDEGIGLLQVDFANKYLGGGVLGHGCVQEEIRFVICPELLVGKLFTECLRPFEALVMLGAERYSNYTGYAGSFEWSGNFEDSTPRDSSGRRQTAIVAIDALHFAQSHHQYREDLMERELNKAYIGFVHWMVTPP--PGVATGNWGCGAFGGDSYLKALLQLMVCAQLGRPLAYYTFGNVEFRDDFHEMWLLFRNDGTTVQQLWSILRSYSRLIKEKSSKEPRENKASKKKLYDFIKEELKKVRDVPGEGASAEAGSSRVAGLGEGKSETSAKSSPELNKQPARPQITITQQSTDLLPAQLSQDNSNSSEDQALLMLSDDEEANAMMEAASLEAKSSVEISNSSTTSKTSSTATKSMGSGGRQLSLLEMLDTHYEKGSASKRPRKSPNCSKAEGSAKSRKEIDVTDKDEKDDIVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . *. *.::.: . .: . . :..* *..:* ::: * ..* * * : .: : * *.* * * : . **.:**::**: :. ** *: :*. * . ***:*: ***: :. ::*: **:.**.:* .:*.* ** :: *: *:*:*:: :::.:** ::::** **:: .*:****:: * *:::**:**:.******:******* * *****::********::. .. **** :: ***** .: ***:***.*:* *.: :*.:. ** . *** ***** :* *:*******:::**** . * *******:* ***::.:**** * *.*:: *:*:**:***** ::.*: ..**.: :*. * * ********* : .*: : :.******* **:: *.. ..**************: ****:*::..* * :.*:***: *: *::.* :: : * .:: :* * . ...* . ... *** ** . :. :... .. . ", "identical_positions": 223, "similar_positions": 186, "identity": "19.32%" }, { "cls_id": "homologset.agr.RGD:620388", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97553-1", "uniprot_id": "EFNA1_RAT", "id": "P97553-1", "name": "Ephrin-A1", "aln": "MEFLWAPLLGLCCSLAAADRHIVFWNSSNPKFREEDYTVHVQLNDYLDIICPHYEDDSVADAAMERYTLYMVEHQEYVTCEPQSKDQVRWKCNQPSAKHGPEKLSEKFQRFTPFTLGKEFKEGHSYYYISKPIYHQETQCLKLKVTVNGKITHSPHAHANPQEKRLQADDPEVQVLHSIGHSAAPRLFPLVWAVLLLPLLLLQTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52793-1", "uniprot_id": "EFNA1_MOUSE", "id": "P52793-1", "name": "Ephrin-A1", "aln": "MEFLWAPLLGLCCSLAAADRHIVFWNSSNPKFREEDYTVHVQLNDYLDIICPHYEDDSVADAAMERYTLYMVEHQEYVACQPQSKDQVRWNCNRPSAKHGPEKLSEKFQRFTPFILGKEFKEGHSYYYISKPIYHQESQCLKLKVTVNGKITHNPQAHVNPQEKRLQADDPEVQVLHSIGYSAAPRLFPLVWAVLLLPLLLLQSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20827-1", "uniprot_id": "EFNA1_HUMAN", "id": "P20827-1", "name": "Ephrin-A1", "aln": "MEFLWAPLLGLCCSLAAADRHTVFWNSSNPKFRNEDYTIHVQLNDYVDIICPHYEDHSVADAAMEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLGKEFKEGHSYYYISKPIHQHEDRCLRLKVTVSGKITHSPQAHDNPQEKRLAADDPEVRVLHSIGHSAAPRLFPLAWTVLLLPLLLLQTP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************* ***********:****:*******:*********.********:* **:***:** *:*********:**:******************** ******************:::* :**:*****.*****.*:** ******* ******:******:*********.*:**********: ", "identical_positions": 173, "similar_positions": 23, "identity": "84.39%" }, { "cls_id": "homologset.agr.RGD:620389", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MA19-1", "uniprot_id": "F1MA19_RAT", "id": "F1MA19-1", "name": "", "aln": "MAPAQRPLLPLLLLLLPLR----ARNEDPARANADRYAVYWNRSNPRFQVSAVGDGGGYTVEVSINDYLDIYCPHYGAPLPPAERMERYILYMVNGEGHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNLVDRPCLRLKVYVRPTNETLYEAPEPIFTSNSSCSGLGGCHLFLTTVPVLWSLLGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52801-1", "uniprot_id": "EFNA2_MOUSE", "id": "P52801-1", "name": "Ephrin-A2", "aln": "MAPAQRPLLPLLLLLLPLR----ARNEDPARANADRYAVYWNRSNPRFQVSAVGDGGGYTVEVSINDYLDIYCPHYGAPLPPAERMERYILYMVNGEGHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNLVDRPCLRLKVYVRPTNETLYEAPEPIFTSNSSCSGLGGCHLFLTTVPVLWSLLGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43921-1", "uniprot_id": "EFNA2_HUMAN", "id": "O43921-1", "name": "Ephrin-A2", "aln": "MAPAQRPLLPLLLLLLPLPPPPFARAEDAARANSDRYAVYWNRSNPRFHAGAGDDGGGYTVEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEAPEPIFTSNNSCSSPGGCRLFLSTIPVLWTLLGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P79727-1", "uniprot_id": "EFNA2_DANRE", "id": "P79727-1", "name": "Ephrin-A2", "aln": "--------MELSLVVFTVVCWVSVWSDD--RIISDRHAVYWNSSNSRFWQ------GEYTVAVSINDYLDVYCPYYESPQP-HSRMERYILFMVNHDGYLTCEHRMRGFKRWECNRPQSPDGPLRFSEKFQLFTPFSLGFEFRPGHEYYYISSPHPNHAGKPCLKLKVYVKPT-SSGYESPEPFLTDQSQRCGADGPCLAVLMLLLVFLLAGV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *:::.: . :* * :**:***** **.** * *** ********:***:* :* * .***:*:*:*** :*: :*:** *********** :*.***:***************************:. ** ..:***:*****:** .: **:***::*.:.. .. .* * : : ::: * * ", "identical_positions": 109, "similar_positions": 49, "identity": "51.17%" }, { "cls_id": "homologset.agr.RGD:62039", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R011-1", "uniprot_id": "PLK3_RAT", "id": "Q9R011-1", "name": "Serine/threonine-protein kinase PLK3", "aln": "--MEPAAGFLSPRPFPRAAAPSSPPAGPGPPASASPRSEPGVLAGPQTPDAS-RLITDPRS-----------------GRTYIKGRLLGKGGFARCYEATDTETSIAYAVKVIPQSRVAKPHQREKIINEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLL--RQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLP--ASLSLPARQLLAAILRASPRDRPSIEQILRHDFFTKGYTP--DRLPVSSCVTVPDLTPPNPARSLFAKVTKSLFGRRKS--KNKNHSEEQDNVSCLVSGLMRTSIGHPDVRPEAPAASALAP------VSLVETAAEDSSPR---------------GTLASSGDGFEEGLTVTTVVESALCALRNCVAFMPPAEQN---PAPLAQPEPLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKH----FSFSVGSVPRALQPQLGILRYFASYMEQHLMKGGDLPSVEEVEVPAPPLLLQWVKTDQALLMLFSDGTVQVNFYGDHTKLILS--GWEPLLVTFVARNRSACTYLASHLRQLGCSP-----DLRQRLRYALRLLRDRSPA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60806-1", "uniprot_id": "PLK3_MOUSE", "id": "Q60806-1", "name": "Serine/threonine-protein kinase PLK3", "aln": "--MEPAAGFLSPRPFPRAAVPSAPPAGPGPPANASPRSEPEVLAGPRAPDPPGRLITDPLS-----------------GRTYTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLL--RQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLP--ASLSLPARQLLAAILRASPRDRPSIEQILRHDFFTKGYTP--DRLPVSSCVTVPDLTPPNPARSLFAKVTKSLFGRKKN--KNKNHSEDQDNVSCLA-----------------PVVSGQAP------ASLIETAAEDSSPR---------------GTLASSGDGFEEGLTVATVVESALCALRNCVAFMPPAEQN---PAPLAQPEPLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKH----FSFSMGSVPRALQPQLGILRYFASYMEQHLMKGGDLPSVEEAEVPAPPLLLQWVKTDQALLMLFSDGTVQVNFYGDHTKLILS--GWEPLLVTFVARNRSACTYLASHLRQLGCSP-----DLRQRLRYALRLLRDQSPA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4B4-1", "uniprot_id": "PLK3_HUMAN", "id": "Q9H4B4-1", "name": "Serine/threonine-protein kinase PLK3", "aln": "--MEPAAGFLSPRPFQRAAAAPAPPAGPGPPPSALRGPELEMLAGLPTSDPG-RLITDPRS-----------------GRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLL--RQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLP--ASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTKGYTP--DRLPISSCVTVPDLTPPNPARSLFAKVTKSLFGRKK---KSKNHAQERDEVSGLVSGLMRTSVGHQDARPEAPAASGPAP------VSLVETAPEDSSPR---------------GTLASSGDGFEEGLTVATVVESALCALRNCIAFMPPAEQN---PAPLAQPEPLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKH----FSFSVGAVPRALQPQLGILRYFASYMEQHLMKGGDLPSVEEVEVPAPPLLLQWVKTDQALLMLFSDGTVQVNFYGDHTKLILS--GWEPLLVTFVARNRSACTYLASHLRQLGCSP-----DLRQRLRYALRLLRDRSPA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N1Z395-1", "uniprot_id": "A0A8N1Z395_DANRE", "id": "A0A8N1Z395-1", "name": "Serine/threonine-protein kinase PLK", "aln": "--MDPSCFTTAQRLSCKIMNPDMFKASPAAPPPAKPSRSK---SEHVKPELA-QVVVDAKT-----------------GRSYCKGKLLGKGGFARCYEMTDLANNKMYAVKVIPQSRVSKPHQREKIINEIELHKSLQHKHVVKFSHHFEDQDNIYIFLELCSRKSLAHIWKARHTLTDPEVRYYLRQIISSLKYLHNKGILHRDLKLGNFFVNENMELRLGDFGLAAKLETVEQRKKTICGTPNYLAPEVLN--RQGHGTESDVWSLGCVMYTLLCGNPPFETLDLKETYKCIKEVKYSLP--SSLTPSAQKLISSILQKNPCDRLTLDQILAHDYFTKGFTP--EKLPPSSCVMVPELNPPSPAKKFFTKMAKSLFGKKKSKTVEKTTSEEKDDISKLVSGMVKHSIGRQMSYKTMGVNEATSPTVQLASSGPLDTPAEEESRKSASRSF--------KGTVASSTDGCDDIPTPSAVAESAMKVLNSCLSSMPTASRN---PPCLVKTKPFIWVTKWVDYSNKYGFGYQLSNQNVGVLFNEGTHLSLCDQRRTVHYCLTNNKH----FSFPANALPEKLQSQKHIVDLMANYMEQNLMEGGDIN-CEDQSSSSSPLLLQWIKTDHALVMLFDNRTLQVNFYTDHTKIILCKPSDASYLVTFISKERVSYSYPLNVLSELGCSP-----ELRQRLHYVVQLLQHYTNA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32562-1", "uniprot_id": "CDC5_YEAST", "id": "P32562-1", "name": "Cell cycle serine/threonine-protein kinase CDC5/MSD2", "aln": "MSLGPLKAINDKQLNTRSKLVHTPIKGNTADLVGKENHFKQTKRLDPNNDHHHQPAQKKKREKLSALCKTPPSLIKTRGKDYHRGHFLGEGGFARCFQIKD-DSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWFRGTFPPSIPSTVMSEAPNFEDIPEEQSLVNFKDCMEKSLLLESMS--SDKIQRQKRDYISSIKSSIDKLEEYHQNRPFLPHSLSPGGTKQKYKEVVDIEAQRRLNDLAREARIRRAQQAVLRKELIATSTNVIKSEISLRILASECHLTLNGIVEAEAQYKMGGLPKSRLPKIKHPMIVTKWVDYSNKHGFSYQLSTEDIGVLFNNGTTVLRLADAEEFWYISYDDREGWVASHYLLSEKPRELSRHLEVVDFFAKYMKANLSRVSTFG--REEYHKDDVFLRRYTRYKPFVMFELSDGTFQFNFKDHHKMAISD----GGKLVTYISPSHESTTYPLVEVLKYGEIPGYPESNFREKLTLIKEGLKQKSTIVTVD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : . . . : : . *: * :*::**:******:: .* .. :*.*.:.:: : . : *:*::.**::*:.:.* ::*:* . *** .*:**:**:*.. ** .: * *:.* :****:: ** ..:**:*.: ::********:*. .* :*::******* * .:** ********:***** :.**. * *:**** ::*:** *.***:: *:: *. ** .:::* .:: .: *: ** .* :* :: :*: : :* :.* *.. . :: .. .: : ***: . .* :.:* :* : . .. ::: . .. :*:* : .. : :.... .*.. : . . . . * : : : *:********.**.****.. :.****:** : : . . * . :. : . *. *. : :: :*.**: :* . . : .: :* :: : . ::: :.: *.*.** .*. * ***::: .: : :* : : * * ::*::* . *:. : ", "identical_positions": 163, "similar_positions": 218, "identity": "22.83%" }, { "cls_id": "homologset.agr.RGD:620390", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52797-1", "uniprot_id": "EFNA3_HUMAN", "id": "P52797-1", "name": "Ephrin-A3", "aln": "-------MAAAPLLLLLLLVPVPLLP------------------------LLAQG----PGGALGNRHAVYWNSSNQHLRREGYTVQVNVNDYLDIYCPHYNSSGVGPGAGPGPGGGAEQYVLYMVSRNGYRTCNASQGFKRWECNRPHAPHSPIKFSEKFQRYSAFSLGYEFHAGHEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPTLPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGTSPKREHLPLAVGIAFFLMTFLAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08545-1", "uniprot_id": "EFNA3_MOUSE", "id": "O08545-1", "name": "Ephrin-A3", "aln": "-------MAAAPLLLLLLLVPVPLLP------------------------LLAQG----PGGALGNRHAVYWNSSNQHLRREGYTVQVNVNDYLDIYCPHYNSS--------GPGGGAEQYVLYMVNLSGYRTCNASQGSKRWECNRQHASHSPIKFSEKFQRYSAFSLGYEFHAGQEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPTLPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGTSPKREHLPLAVGIAFFLMTLLAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LV88-1", "uniprot_id": "A0ABK0LV88_RAT", "id": "A0ABK0LV88-1", "name": "Ephrin-A3", "aln": "MQGRILGWAQVPGLGSCKLMPSDCRPSGQASPLFFCFLPHSRGPRYFQYRLKALGGPTTPGSTHEKSSRCVQRHSSKSLRREGYTVQVNVNDYLDIYCPHYNSS--------GPGGGAEQYVLYMVNLSGYRTCNASQGSKRWECNRQHASHSPIKFSEKFQRYSAFSLGYEFHAGQEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPTLPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGTSPKREHLPLAVGIAFFLMTLLAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1Q1X6-1", "uniprot_id": "A0A8M1Q1X6_DANRE", "id": "A0A8M1Q1X6-1", "name": "Ephrin-A3", "aln": "-----MALAAVS-LYLLALAWTNLRP--------------------------VHG---------NNRHAVYWNSSNIHLRREGYTVQVSVNDYLDIYCPHYNQSQ----RGSLERGVAEQYVLYMVSYRGYRTCDPQMGFKRWECNRPHAPHAPIKFSEKFQRYSAFSLGYEFNVGHEYYYISTPIHHHGHSCLRLRVYVCCSTVSNSDDDSSP--PDYTVRP--KLHDIDEF---NPEIPKLEKSVSGSSPSGDRLLITV-ATLLLAALLVS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .. * * * . * : . *. **********.*************.* * *********. *****:.. * ******* **.*:********************:.*:******** *: .***::*:***::.*:*.:.. * *::*: * *:: :::* **::******:**:**. ::* ::* :::* ::*.*", "identical_positions": 118, "similar_positions": 53, "identity": "43.22%" }, { "cls_id": "homologset.agr.RGD:620391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52803-1", "uniprot_id": "EFNA5_HUMAN", "id": "P52803-1", "name": "Ephrin-A5", "aln": "MLHVEMLTLVFLVLWMCVFSQDPGSKAVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDKVENSLEPADD-TVHESAEPSRG-ENAAQTPRIPSRLLAILLFLLAMLLTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97605-1", "uniprot_id": "EFNA5_RAT", "id": "P97605-1", "name": "Ephrin-A5", "aln": "MLHVEMLTLLFLVLWMCVFSQDPGSKVVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVRDRVFDVNDKVENSLEPADD-TVHESAEPSRG-ENAAQTPRIPSRLLAILLFLLAMLLTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08543-1", "uniprot_id": "EFNA5_MOUSE", "id": "O08543-1", "name": "Ephrin-A5", "aln": "MLHVEMLTLLFLVLWMCVFSQDPGSKVVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDKVENSLEPADD-TVHESAEPSRG-ENAAQTPRIPSRLLAILLFLLAMLLTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PZ39-1", "uniprot_id": "A0A8M1PZ39_DANRE", "id": "A0A8M1PZ39-1", "name": "EPH-related receptor tyrosine kinase ligand 7", "aln": "MPQVEMFYLLFSSLWMSVLGLDPASKVVADRYAVFWNRTNPRFYRGDYHIDVCINDYLDVYCPHYMDTVPEERTERYVLYMVNYDGYSSCDHTAKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYYYISSTLAENGRRSCLRLKVFVRPTNNCDKS---HDRVDKFDDRSINSIENNNDGTSHESAEPSRSDVNSAGRVQTVGPLLASVLVLLASLSSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :***: *:* ***.*:. **.**.*******:** :**** ****************:**** *:***::**********:****:****:******************************************:****::.:*******:*********.* *: :*** ..:*: **:* :* * ********. *:* : . *** :*.*** * :*", "identical_positions": 161, "similar_positions": 39, "identity": "70.0%" }, { "cls_id": "homologset.agr.RGD:620392", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62253-1", "uniprot_id": "UB2G1_HUMAN", "id": "P62253-1", "name": "Ubiquitin-conjugating enzyme E2 G1", "aln": "MTELQSALLLRRQLAELNKNPVEGFSAGLIDDNDLYRWEVLIIGPPDTLYEGGVFKAHLTFPKDYPLRPPKMKFITEIWHPNVDKNGDVCISILHEPGEDKYGYEKPEERWLPIHTVETIMISVISMLADPNGDSPANVDAAKEWREDRNGEFKRKVARCVRKSQETAFE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62255-1", "uniprot_id": "UB2G1_RAT", "id": "P62255-1", "name": "Ubiquitin-conjugating enzyme E2 G1", "aln": "MTELQSALLLRRQLAELNKNPVEGFSAGLIDDNDLYRWEVLIIGPPDTLYEGGVFKAHLTFPKDYPLRPPKMKFITEIWHPNVDKNGDVCISILHEPGEDKYGYEKPEERWLPIHTVETIMISVISMLADPNGDSPANVDAAKEWREDRNGEFKRKVARCVRKSQETAFE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62254-1", "uniprot_id": "UB2G1_MOUSE", "id": "P62254-1", "name": "Ubiquitin-conjugating enzyme E2 G1", "aln": "MTELQSALLLRRQLAELNKNPVEGFSAGLIDDNDLYRWEVLIIGPPDTLYEGGVFKAHLTFPKDYPLRPPKMKFITEIWHPNVDKNGDVCISILHEPGEDKYGYEKPEERWLPIHTVETIMISVISMLADPNGDSPANVDAAKEWREDRNGEFKRKVARCVRKSQETAFE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VFR8-1", "uniprot_id": "Q9VFR8_DROME", "id": "Q9VFR8-1", "name": "E2 ubiquitin-conjugating enzyme", "aln": "MSELQASLLLNRQLSELQRHPVEGFSAGLVSDSDIFKWEVVIIGPPDTLYEGGFFKAHLIFPKEYPLRPPKMKFITEIWHPNIDKAGDVCISILHEPGDDKWGYEKAEERWLPVHTVETILLSVISMLTDPNDESAANVDAAKEYREN-YAEFKRKVTRCVRRSQE-EVE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:***::***.***:**:::*********:.*.*:::***:************.***** ***:******************:** ************:**:****.******:******::******:***.:*.********:**: .******:****:*** .*", "identical_positions": 130, "similar_positions": 34, "identity": "76.47%" }, { "cls_id": "homologset.agr.RGD:620393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UV70-1", "uniprot_id": "PDP1_MOUSE", "id": "Q3UV70-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "aln": "-MPAPTQLFFPLVRNCELSRIYGTACYCHHKHLCCSPPYIPQNRLRYTPHPAYATFCRPRENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYS---FKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTR-GMLLGVFDGHAGCACSQAVSER-LFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRT-YWQELIDLNTGESADIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLR--VAFSGATACVAHVDGVD--LHVANTGDSRAMLGVQE-EDGSWSAVTLSNDHNAQNERELERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGY------KVTLGQMHGLLTERRAKMSS----------VFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFN-SHVVGAYQNQEQ---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88483-1", "uniprot_id": "PDP1_RAT", "id": "O88483-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "aln": "-MPAPTQLFFPLVRNCELSRIYGTACYCHHKHLCCSPPYIPQNRLRYTPHPAYATFCRPRENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYS---FKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTR-GMLLGVFDGHAGCACSQAVSER-LFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRT-YWQELIDLNTGESADIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLR--VAFSGATACVAHVDGVD--LHVANTGDSRAMLGVQE-EDGSWSAVTLSNDHNAQNERELERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGY------KVTLGQMHGLLTERRAKMSS----------VFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFN-SHVVGAYQNQEQ---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P0J1-1", "uniprot_id": "PDP1_HUMAN", "id": "Q9P0J1-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "aln": "-MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYS---FKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTR-GMLLGVFDGHAGCACSQAVSER-LFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRT-YWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLR--VAFSGATACVAHVDGVD--LHVANTGDSRAMLGVQE-EDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGY------KVTLGQMHGLLTERRTKMSS----------VFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFN-SHVVGAYQNQE----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3Q1-1", "uniprot_id": "Q9W3Q1_DROME", "id": "Q9W3Q1-1", "name": "", "aln": "--------MFKFVLNDAAS-------------------YVRSNVREFSLN--------------------ALRLLPQLPQLSPYDVNLVLRENEFV---YNFP-VDG----VIRSYETNQLGSNWPCEDSRTEASFLHRN-GFICGIFDGHAGAACGQVVSKR-LLRYVSAATLPRQVLREQM---KQGADSQSFLKCHNDNVDFVSMIKP-MYEASFLK-YVNQLL-----ETPQRDVSSELVNAFLQLDEEISQEALTSN-----DVRTMN--VALSGAVACLVHIEGLQ--MHVASTGDCGAVLGVLDPQTQQWHSKKLNIEHNADNMSEVRRILAEHPKEEHETVIRNGRLLSQLAPLRAFGDFRYKWSQEIMQQKVLPMFG-------VQAMAPNYYTPPYLTARPDVQQHELGPNDKFLVIASDGLWDFLPPSEVVSLVGEHINSKKILEPMRLPEG------DTTLQEISQQLAERKAGLTR----------KPVDQNAATHLIRHALGGTDYG-IEHSKISYYLTLPRDAVRLYRDDITITVIYFNSEHIAKLHSDVDQTEVTAPVA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12511-1", "uniprot_id": "PDP1_YEAST", "id": "Q12511-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "aln": "MSPLTRTVAIKKTVKVLSKCQSGREYTQKFLQRAYSTSHANSTYYSRTKLFISSHSKALNIALLSGSLLLTYSYYSPKKILSLDTINGIKDYSTNTSGNINMPSPNPKGTETQKSQRSQNDQSVLILNDSKIEAKLHDREESHFVNRGTGIFRYDVAQLPSNHPIEDDHVEQIITIPIESEDGKSIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQVYDQNKTVFHSDPNQLIDSAISKGFLKLDNDLVIESFRKLFQDPNNTNIANTLPAISGSCALLSLYNSTNSILKVAVTGDSRALICGLD-NEGNWTVKSLSTDQTGDNLDEVRRIRKEHPGE--PNVIRNGRILGSLQPSRAFGDYRYKI-KEVDGKPLSDLPEVAK--LYFRREPRDFKTPPYVTAEPVITSAKIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNMNLAPVKAEPGKLPKVIDVSEDKEAQRPAFRYKDNNSSSPSGSNPEYLIEDKNVATHLIRNALS----AGGRKEYVSALVSIPSPMSRRYRDDLTVTVAFFGDSGTPSIVSNATSIVMNPEATTKPKPRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : .. : . *: :* : . :.* : . ::: : :* : *. . . . : . * .* *:: : :. * :.. ::. * . : : : . .: :.. : :.* :**::: *: : . *:**: * : :. : ::** ***. *:: : : .* .*. ::..:* *:.*: *** . .*:::.*:*. * * ***** ::* :: : : : . :: ****:**.* : .: : **:*:.:***:: : .::. :* . : *: ..: : : * . *:*.******:*:. . :. :* :::* * ****:*: * *. . .: ", "identical_positions": 78, "similar_positions": 147, "identity": "13.4%" }, { "cls_id": "homologset.agr.RGD:620394", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JM80-1", "uniprot_id": "PHAG1_RAT", "id": "Q9JM80-1", "name": "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1", "aln": "MGPAG-SALSSGQM-----------QMQMVLWGSLAAVAMFFLITFLILLCSSCDRDKKPRQHSGDHESLMNVPSDKEMFSHSATSLTTDALASSEQNGVLTNGDILSEDSTMTCMQHYEEVQTSASDLLDSQDSTGKAKCHQSRELPRIPPENAVDAMLTARAADGDSGPGVEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAD-----KSQGGKSKSTSALKELQGAHAEGKADFAEYASVDRNKKCRHSTNAES----ILGTSSDLDEETPPPVPVKLLDENANLPEKGEHGAEEQAPEAPSGHSKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQSAHKPG-----PESTCQCPQGPPQRSSSSCNDLYATVKDFEKTPNSISMLPPARRPGEEPEPDYEAIQTLNREDDKVPLGTNGHL--VPKENDYESIGDLQQGRDVTRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1F9-1", "uniprot_id": "PHAG1_MOUSE", "id": "Q3U1F9-1", "name": "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1", "aln": "MGPAG-SVLSSGQM-----------QMQMVLWGSLAAVAMFFLITFLVLLCSTCDREKKPRQHSGDHENLMNVPSDKDMFSHSATSLTTDALASSEQNGVLTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKAKCHQSRELPRIPPENAVDEILTARAADTELGPGVEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAD-----KGQGGKSKSTSALKELQGAPMEGKADFAEYASVDRNKKCRHSANAES----ILGTCSDLDEESPPPVPVKLLDENANLPQEGGGQAEEQAAEGTGGHSKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQSAHKPGPCMKGPESACHSMKGLPQRSSSSCNDLYATVKDFEKTPNSISTLPPARRPSEEPEPDYEAIQTLNREDEKVPLETNGHH--VPKESDYESIGDLQQCRDVTRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWQ8-1", "uniprot_id": "PHAG1_HUMAN", "id": "Q9NWQ8-1", "name": "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1", "aln": "MGPAG-SLLGSG-------------QMQITLWGSLAAVAIFFVITFLIFLCSSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVES----ILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPN--STLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDYESISDLQQGRDITRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6R8-1", "uniprot_id": "A0ACD6B6R8_DANRE", "id": "A0ACD6B6R8-1", "name": "", "aln": "MAPALSAVLGSGAAGSEVAGAAVLAKGELALVGTITGLTAFLLLSVLLLLLCASCQGQKKGGPPGDHENLMNGVSEKETCSQSVESHGTDLAVSSSHNGPLTSGTVLTDT--------MDTSPQPSEDMLSSQSEIRSSKYHQDRELPSIPPTDSLKAAAVDAQVTSG-----DGTYEVLKESTSRDVSVEDCLYETVKELKDIGLPNGTLSPEEPPAPLLNGHPSPATPDHTMLPNGVEYASVNLSKKSRYSTDLEARRSAAIVNSEEPEEEKPPPVPDKVLDENENQQIPNG----------------RLHSPLLTPELQDKVSPDSELSDLYSTVAKNPVKEAEND------YSSIGEIKGIMPESTS--SDLYATVGDEYSMVS---GSQPSEGLTENAEPGYETIK-ISKASEEAHLGN------GIVEPDYESVGELGLNGDISRL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.** : *.** : ::.* *:::.:: *::::.*::* .:. : :* .****.*** *:*: *:*. * ** .**.:** **.* :*:: : .:.*:*.**.. ..* **.**** *** .::. . . :*.*****:*:*:: ***********:*::. . . : .. . . .: .*****: .**.* *.: *: : .. : :** ***** *:**** * *: * ... :* . .:.*:* :**:* * : . *: :* .*.* .****** * . . *: *:.**.**:*: :.: .::. * . * ****:.:* *::**", "identical_positions": 128, "similar_positions": 127, "identity": "28.32%" }, { "cls_id": "homologset.agr.RGD:620395", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E7F7V2-1", "uniprot_id": "E7F7V2_DANRE", "id": "E7F7V2-1", "name": "", "aln": "MQKGIRLNDGHVTYLGLLAKKDGTRRGCLSKKSS-------DNTKWHTKWFALLQNMLFYFESESSSRPSGLYLLEGCVCDRSPSPKPSLSAKECL-------------EKQ-YYFTVSFNHENQKALELRTEDVKDCDEWVAAISHASYRNLAT-------------------------EHETLMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLK--SEIAAMLKDNEKIQS-SPTTAPSDDDSEIKKIKKVQSFLRGWMCRRKWKTIIQDYIRSPHAESMRKRNQVVFSMLEAEAEY---VQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLHQIFYQGLKARIASWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLLKQYEAKPDCEERTLET--------------FLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELSRIMHDEVSETENIR---------KNLAIERMIVEGCEILLDTSQTFVRQGSLIQVPMSEK---GKITRGRLGSLSLKKEGERQCFLFSKHLIICTRGSGG-----------------------------KLHLTKNGVVSLIDCTLIEEPEGTDDESKSEKSGQDMEHLDFKIVVEPKDSQSFTFILVASSRQEK--------------------SAWTSDISQCIDNIR--CNGLMMNAFEENSKVTVPQMIK-------------SDASLYCDDVDIRFSKMMNSC----KVLQIRYASVERLLERLTDLRFLSIDFL----------NTFLHSYRVFTSADVVLDKLITIYKRPISAIPA---RSLELFFASSQNNKLLYGEPPK---------SPRASRKFSSPPPLAITK-------TSSPNRRRKLSLNIPIITGGKALDLAALSCSSNGYASMYSTMSPFSKTTLDINKLYVSSPITSKIPDEGEGKTDKAD---EIS-LCKQDN---SVREESDNDQIQSDEAEAEVSPTKSPTTPKNVKCKNSSEFSLFSYNNGMVMSSCRELD-NNRSALSAASAFAIATAGANEGTPTKEKYRRMSLASTGFPTDQRNGDKEFVIRR---AATNRVLNVLRHWVSKHSQDFETNTELKMKVISFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQICLEEVLQMAEGGKSESFENHSALEIAEQLTLLDHLVFKVIPYEEFFGQGWMKND-----------KNEKTPYIMKTTKHFNDISDLIATEILRCEDVNVRVAVMEKWVAVADICRCLHNYNAVLEITSSLNRSSIFRLKKTWLKVSKQTKTVIDKLQKLVSSEGRFKNLREALKNCDP--PCVPYLGMYLTDLAFIEEGTPNYTEDNLVNFSKMRMISHIIREIRQFQQTAYKIDYQPKAALYLLDRSAVMEEEGLYEASLRIEPKVPN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q13972-1", "uniprot_id": "RGRF1_HUMAN", "id": "Q13972-1", "name": "Ras-specific guanine nucleotide-releasing factor 1", "aln": "MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSS-------DNTKWQTKWFALLQNLLFYFESDSSSRPSGLYLLEGCVCDRAPSPKPALSAKEPL-------------EKQ-HYFTVNFSHENQKALELRTEDAKDCDEWVAAIAHASYRTLAT-------------------------EHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLK--AEITSLLKDNERIQS-TQTVAPNDEDSDIKKIKKVQSFLRGWLCRRKWKTIIQDYIRSPHADSMRKRNQVVFSMLEAEAEY---VQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLHQIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLLKHYEAKPDCEERTLET--------------FLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELSRIMHDEVSETENIR---------KNLAIERMIIEGCEILLDTSQTFVRQGSLIQVPMSEK---GKITRGRLGSLSLKKEGERQCFLFSKHLIICTRGSGG-----------------------------KLHLTKNGVISLIDCTLLEEPESTEEEAKG--SGQDIDHLDFKIGVEPKDSPPFTVILVASSRQEK--------------------AAWTSDISQCVDNIR--CNGLMMNAFEENSKVTVPQMIKRTREGTREAEMSRSDASLYCDDVDIRFSKTMNSC----KVLQIRYASVERLLERLTDLRFLSIDFL----------NTFLHSYRVFTTAIVVLDKLITIYKKPISAIPARWLRSLELLFASGQNNKLLYGEPPK---------SPRATRKFSSPPPLSITK-------TSSPSRRRKLSLNIPIITGGKALDLAALSCNSNGYTSMYSAMSPFSKATLDTSKLYVSSSFTNKIPDEGDTTPEKPE---DPSALSKQSSE-VSMREESDIDQNQSDDGDTETSPTKSPTTPKSVKNKNSSEFPLFSYNNGVVMTSCRELD-NNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVIRR---AATNRVLNVLRHWVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANIIRTLTQEDPGDNQITLEEITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLE-----------KNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDP--PCVPYLGMYLTDLAFIEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPKLPT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P27671-1", "uniprot_id": "RGRF1_MOUSE", "id": "P27671-1", "name": "Ras-specific guanine nucleotide-releasing factor 1", "aln": "MQKAIRLNDGHVVTLGLLAQKDGTRKGYLSKRSA-------DNPKWQTKWFALLQNLLFYFESDSSPRPSGLYLLEGSICKRAPSPKRGTSSKESG-------------EKQQHYFTVNFSNDSQKTLELRTEDAKDCDEWVAAIARASYKILAT-------------------------EHEALMQKYLHLLQVVETEKTVAKQLRQQLEDGEVEIERLKTEVTITNLIKDNDRIQSSNKAGSADDEDSDIKKIKKVQSFLRGWLCRRKWKNIIQDYIRSPHADSMRKRNQVVFSMLEAEAEY---VQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLHQIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLLKQYEAKPDCEERTLET--------------FLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELSRIMHDEVSETENIR---------KNLAIERMITEGCEILLDTSQTFVRQGSLMQMSLSEK---SKSSRGRLGSLSTKKEGERQCFLFSKHLIICTRGSGG-----------------------------KLHLTKNGVISLIDCTLLDEPENLDDEAKG--AGPEIEHLEFKIGVEPKDSLPFTVILVASTRQEK--------------------AAWTSDIIQCVDNIR--CNGLMMNAFEENSKVTVPQMIK-------------SDASLYCDDVDIRFSKTMNSC----KVLQIRYASVERLLERLTDLRFLSIDFL----------NTFLHSYRVFTNAMVVLDKLINIYRKPMSAIPA---RSLELLFSSSHNAKLLYGDAPK---------SPRASRKFSSPPPLAIG--------TSSPSRRRKLSLNIPIITGGKALELASLGCSSDSYANIHSPISPFGKTTLDTGKLCMASSLP-KTPEEIDVPATIPEKPGELSASRKHSS--DVLKEESEDDQNHSDEDNTEVSPVKSPPTPKSFLNRTITEFPFFNYNNGILMTTCRDLVDNNRSTLSATSAFAIATAGANEGPSNKEVFRRMSLANTGFSSDQRNIDKEFVIRR---AATNRVLNVLRHWVTKHTQDFDTDDTLKYRVICFLEEVMHDPDLLTQERKAAANIIRTLTLEETTEQHSMLEEVILMTEGVKTEPFENHPALEIAEQLTLLDHLVFKSIPYEEFFGQGWMKAE-----------KYERTPYIMKTTKHFNHVSNFIASEIIRNEDISARASAIEKWVAVADICRCLHNYNAVLEITSSINRSAIFRLKKTWLKVSKQTKSLLDKLQKLVSSDGRFKNLRESLRNCDP--PCVPYLGMYLTDLVFIEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTTYKIDPQPKVIQYLLDESFMLDEESLYESSLLIEPKLPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28818-1", "uniprot_id": "RGRF1_RAT", "id": "P28818-1", "name": "Ras-specific guanine nucleotide-releasing factor 1", "aln": "MQKAIRLNDGHVVSLGLLAQRDGTRKGYLSKRSS-------DNPKWQTKWFALLQNLLFYFESDSSSRPSGLYLLEGSICKRMPSPKRGTSSKES--------------DKQHHYFTVNFSNDSQKSLELRTDDSKDCDEWVAAIARASYKILAT-------------------------EHEALMQKYLHLLQVVETEKTVAKQLRQQLEDGEVEIERLK--AEIANLIKDNERIQS-NQLVAPEDEDSDIKKIKKVQSFLRGWLCRRKWKNIIQDYIRSPHADSMRKRNQVVFSMLEAEAEY---VQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLHQIFYQGLKARIASWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLLKQYEAKPDCEERTLET--------------FLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELSRVMHDEVSETENIR---------KNLAIERMITEGCEILLDTSQTFVRQGSLIQVPMSEK---GKINKGRLGSLSLKKEGERQCFLFSKHLIICTRGSGS-----------------------------KLHLTKNGVISLIDCTLLDDPENMDDDGKG--Q--EVDHLDFKIWVEPKDSPPFTVILVASSRQEK--------------------AAWTSDIIQCVDNIR--CNGLMMNAFEENSKVTVPQMIK-------------SDASLYCDDVDIRFSKTMNSC----KVLQIRYASVERLLERLTDLRFLSIDFL----------NTFLHSYRVFTDAVVVLDKLISIYKKPITAIPA---RSLELLFSSSHNTKLLYGDAPK---------SPRASRKFSSPPPLAIG--------TSSPVRRRKLSLNIPIITGGKALELASLGCPSDGYTNIHSPISPFGKTTLDTSKLCVASSLT-RTPEEIDMTTLE-----ESSGFRKPTS--DILKEESDDDQ--SDVDDTEVS----PPTPKSFRNRITQEFPLFNYNSGIMMT-CRDLMDSNRSPLSATSAFAIATAGANESPANKEIYRRMSLANTGYSSDQRNIDKEFVIRR---AATNRVLNVLRHWVTKHSQDFETDDLLKYKVICFLEEVMHDPDLLPQERKAAANIMRTLTQEEITENHSMLDELLLMTEGVKTEPFENHSAMEIAEQLTLLDHLVFKSIPYEEFFGQGWMKAD-----------KNERTPYIMKTTRHFNHISNLIASEILRNEEVSARASTIEKWVAVADICRCLHNYNAVLEITSSINRSAIFRLKKTWLKVSKQTKSLFDKLQKLVSSDGRFKNLRETLRNCDP--PCVPYLGMYLTDLAFLEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTTYKIEPQPKVTQYLVDETFVLDDESLYEASLRIEPKLPT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07866-1", "uniprot_id": "LTE1_YEAST", "id": "P07866-1", "name": "Guanine nucleotide exchange factor LTE1", "aln": "MEIFSQKDYYPTPSSNVISYESDCVSKPVNSADLPALIVHLSSPLEGVDYNASADFFLIYRNFITPQDLHDLLIYRFRWCIREITTNAAKAKRRRIGEVALVRTFVLLRHSILNYFVQDFLPNITLRLRLIEFLNDKHIEQYPKIISSCIINLKKNWVHCSKLVWENIELNEPDKLDFDAWLHYSLKDFTQLESLHKRGSRLSIYARQSFASPDFRNQSVLSLYKTSDVFRLPEKLQSSNSSKNQRSPSMLLFPDNTSNVYSKHRIAKEPSVDNESEDMSDSKQKISHLSKVTLVSTLMKGVDYPSSYAVDKIMPPTPAKKVEFILNSLYIPEDLNEQSGTLQGTSTTSSLDNNSNSNSRSNTSSMSVLHRSAIGLLAKWMKNHNRHDSSNDKKFMSAIKPANQKPEMDAFVKYVVSISSLNRKSSKEEEEEFLNSDSSKFDILSARTIDEVESLLHLQNQLIEKVQTHSNNNRGPTVNVDCERREHIHDIKILQQNSFKPSNDNFSAMDNLDLYQTVSSIAQSVISLTNTLNKQLQNNESNMQPSPSYDALQRRKVKSLTTAYYNKMHGSYSAESMRLFDKDNSSSRTDENGPQRLLFHETDKTNSEAITNMTPRRKNHSQSQKSMTSSPLKNVLPDLKESSPLNDSREDTESITYSYDSELSSSSPPRDTVTKKSRKVRNIVNNTDSPTLKTKTGFLNLREFTFEDTKSLDEKKSTIDGLEKNYDNKENQESEYESTKKLDN--------SLDASSEANNYDITTRKKHSSCNHKIKQAVVRPASGRISISRVQSIAITPTKELSIVDPEQNKSNSVIEEISEIEPLNLEYNKKSALYSDTSSTVIS---ISTSKLFESAQNSPLKQTQNPQREFPNGTSVSETNRIRLSIAPTIESVVSDLNSITTGSTVETFETSRDLPVPHQRIINLREEYQRGNQDIISNTSSLHELKTIDLSDSNNDLESPSTHAKNNKYFFSPDDGSIDVASPMKNVEELKSKFLKNESETNSNISGSVLTMDDIDINDTSSARNTRRANSESAFTGSLNKKNLNEIANMLDDSINDDPITVALMKLEGTYEKIPEKPENTK--SSDAIGIKTSKLADEVEMLNLNNLPSFQNSPAEKRKSLLIERRRQTIMNIPFTPDQSEKEGFTSSSPEKIDVSANVDVAVQAAQIQELIGQYRIHDSRLMISNNESHVPFILMYDSLSVAQQMTLIEKEILGEIDWKDLLDLKMKHEGPQVISWLQLLVRNETLSGIDLAISRFNLTVDWIISEILLTKSSKMKRNVIQRFIHVADHCRTFQNFNTLMEIILALSSSVVQKFTDAWRLIEPGDLLTWEELKKIPSLDRNYSTIRNLLNSVNPLVGCVPFIVVYLSDLSANAEKKDWILEDKVVNYNKFDTNVQIVKNF--IQRVQWSKFYTFKVNHELLSKCVYISTLTQEEINELST-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : : . .::: ... :.. . ... ..: * : :*:* : :. .* : . * * :.: . : :. .. **. .* : *.* .. * . * :. * . . ::.: :* .: : . :: **.: . :.. : : : ::: :::** . . . : :. : : : :.:. .: : ..: . : : .:.* * .:* :*: . : :.: .* * :: *. : .:.* *.: .. ::. :* ..* : : : * * :. *.: :. : .:*: ::* ::* : .. :.:: : :*: :: . :* *:: * .. : * :.* .: . *. .:: . :: : :.:: .** : : : . .: ::. ::*: :* . : :. . . : :: **: .: : :: : : :.... : : .:. *: ...* : . .:.. : : : :. * ..* . :. .:*: : :* : :.:*: : :** * :::.: : : * *** .:: ** * .** * :* ** . :.*: .: : . . * *:.:.. : : :* :* . ::: : * . :* *.:* * : *: * ::* .*.: *.*. . : * ::*: .:. . *.: : . *. .: : *. . :: . . :::**: :. *. : . .:. : * .: . . :. :: .. . . : *: . :: . . * : * * ..: : *:: . : * : : : :: :: : :. . .*: : . :. . : : * : : ..: : : : : ::.:*:*:**::: :: * :::::. : : * . * : :** : * :**: :. . : .::::: *** ** ::*:*:::** ::. * : ::..:* :. ::*:*: * : .:..:*: *.. :* ***:: :**:** * . ** :**:.*: :*:::: :*:. :. *. *:.. :. * . ", "identical_positions": 153, "similar_positions": 487, "identity": "10.52%" }, { "cls_id": "homologset.agr.RGD:620396", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Y9-1", "uniprot_id": "KLOT_RAT", "id": "Q9Z2Y9-1", "name": "Klotho", "aln": "MPAR------APPRRLPRLLLLRLLSLHLLLLTLR-------------------------ARCLSAEPGQGAQTWARFARPPVPEASGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHHPRAIPEDSPIVMAPSGAPLPPLPSTGDVASDSYNNVYRDTEGLRELGVTHYRFSISWARVLPNGTAGTPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSSRLGYLVAHNLLLAHAKVWRLYNTSFRPTQGGRVSIALGSHWITPRR-MTDYHIRECQKSLDFVLGWFAKPIFIDG-DYPKSMKNNLSSLLPDFTESEKRFIRGTADFFALSFGPTLSFQLLDPSMKFRQLESPSLRQLLSWIDLEYNHPQIFIVENGWFVSGTTRRDDAKYMYYLKKFIMESLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKELLPKSSALFYQKLIENNGFPPLPENQPLEGTFPCDFAWGVVDNYIQVDPTLSQFTDPNVYLWDVHHSKRLIKVDGVVAK--KRKPYCVDFSAIRPQITLLREMRVTHFRFSLDWALILPLGNQTQVNRTVLHFYRCMVSELVHANITPVVALWQPATPHQGLPHALAKHGAWENPHTALAFADYANLCFEELGHWVKFWITINEPNSRNMTYRAGHHLLKAHALAWHLYDDKFRAAQKGKISIALQVDWIEPACPFSQKDKEVAERVLEFDVGWLAEPIFGSGDYPHVMREWLNQKN-----NFLLPYFTEDEKKLIRGSFDFLALSHYTTILVDWEKED-------PIKYNDYLEVQEMTDITWLNSPNQ-VAVVPWGLRKALNWLRFKYGDLPMFVTANGIDDDPHAEQDSLRMYYIKNYVNEALKAYVLDGINLCGYFAYSLSDRSVPKSGFYRYAANQFEPKPSIKHYRKIIDNNGFLGSGTLGRFCPEEYTVCTGCGFFQTRKSLLAFISFLVFAFVTSLALIYYYSKKGRRRYK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35082-1", "uniprot_id": "KLOT_MOUSE", "id": "O35082-1", "name": "Klotho", "aln": "MLAR------APPRRPPRLVLLRLLLLHLLLLALR-------------------------ARCLSAEPGQGAQTWARFARAPAPEAAGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHHSGAAPSDSPIVVAPSGAPSPPLSSTGDVASDSYNNVYRDTEGLRELGVTHYRFSISWARVLPNGTAGTPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSSRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGRVSIALSSHWINPRR-MTDYNIRECQKSLDFVLGWFAKPIFIDG-DYPESMKNNLSSLLPDFTESEKRLIRGTADFFALSFGPTLSFQLLDPNMKFRQLESPNLRQLLSWIDLEYNHPPIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKELLPKSSALFYQKLIEDNGFPPLPENQPLEGTFPCDFAWGVVDNYVQVDTTLSQFTDPNVYLWDVHHSKRLIKVDGVVAK--KRKPYCVDFSAIRPQITLLREMRVTHFRFSLDWALILPLGNQTQVNHTVLHFYRCMISELVHANITPVVALWQPAAPHQGLPHALAKHGAWENPHTALAFADYANLCFKELGHWVNLWITMNEPNTRNMTYRAGHHLLRAHALAWHLYDDKFRAAQKGKISIALQADWIEPACPFSQNDKEVAERVLEFDIGWLAEPIFGSGDYPRVMRDWLNQKN-----NFLLPYFTEDEKKLVRGSFDFLAVSHYTTILVDWEKED-------PMKYNDYLEVQEMTDITWLNSPSQ-VAVVPWGLRKVLNWLRFKYGDLPMYVTANGIDDDPHAEQDSLRIYYIKNYVNEALKAYVLDDINLCGYFAYSLSDRSAPKSGFYRYAANQFEPKPSMKHYRKIIDSNGFLGSGTLGRFCPEEYTVCTECGFFQTRKSLLVFISFLVFTFIISLALIFHYSKKGQRSYK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UEF7-1", "uniprot_id": "KLOT_HUMAN", "id": "Q9UEF7-1", "name": "Klotho", "aln": "MPAS------APPRR-PRPPPP-SLSLLLVLLGLG-------------------------GRRLRAEPGDGAQTWARFSRPPAPEAAGLFQGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHWINPRR-MTDHSIKECQKSLDFVLGWFAKPVFIDG-DYPESMKNNLSSILPDFTESEKKFIKGTADFFALCFGPTLSFQLLDPHMKFRQLESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFPPLPENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKVDGVVTK--KRKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQADWIEPACPFSQKDKEVAERVLEFDIGWLAEPIFGSGDYPWVMRDWLNQRN-----NFLLPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKED-------PIKYNDYLEVQEMTDITWLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILDGINLCGYFAYSFNDRTAPRFGLYRYAADQFEPKASMKHYRKIIDSNGFPGPETLERFCPEEFTVCTECSFFHTRKSLLAFIAFLFFASIISLSLIFYYSKKGRRSYK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GMY9-1", "uniprot_id": "A0AC58GMY9_DANRE", "id": "A0AC58GMY9-1", "name": "", "aln": "MAGGNRGTWGKPSRRKSVILWRPELRSAWIPIYPSSAWVIIDRFPERTTTKKTGPDGLHHSEGTASDPGAGQHTWDTFSKLPYPDDKAFLYDTFPDKFMWAVGTAAYSVEGAWEKDGKGKSIWDTFTRG-------------------GTRVSRGDVGSDSYHNIPGDLRALQQLGVSHYRFSLSWPRIFSNGTKESYNDKGVEYYKNLIRGLKDIKVQPVVTLYHWDLPDSLQTLFGGWSNSVMVELFRDYADFCFKTFGSDVKFWITIDNPFVVAWHGYGTGVVAPGIKNDSDLPFRVGHNLLKAHAAAWHLYDERYRAAQGGRVSMALGSHWIKPSR-TRQESRKACQRSLNFVLGWFARPLFVDG-DYPPCMKDNLTHRLPSFTEAESAYVNGTADFFALSHGPALSFQLINDSLRFGQTEDLGLRMLLYWVRAEYNNPPIFVVESGWYGSGNTKTKDAKHMYYLKRFIMETLKAIHVDRVNVIGYTAWSLLDGYEWYREYAIRRGLFYVDFNTPDLKREPKASATFYSKLIEKNGFPQLPENRPAHGAFPCDFAWGVAANSIQVDTTPTQFTDTNVYIWNISGNGELKKLPGLQAPHLRRTPHCADYGSIRQQVSDLLRMQVSHFHFSLNWSSIVPTGHVSDANETLLRYYYCFVSELQKVNITPVVTLWHHTGKLSSLPAPMEASDGWQSEKTVQAFVDYARLCFHRLGAHVKLWITLNEPNDEDLEYTVGHQLLRAHALAWHVYDREFRKAQGGKASLVLHMDWVEPAFSFNREDVAPADRVLDFRVGWFAEPIFGKGDYPAVMRSWLQQRNTIDLFNYHLPTFSEEDRLLVKGTYDFFAISHFTTSMVYDGVED-------KYTFKDKLQVQLISDVTWIMSPRRNSPVVPWGLRKALNWVNSRYKGVPIYVMANGVQEDTARFKDSLRSYYLYNYVNEALKAYMLDAVNLKGYFAYAFSDQRDPGFGMYGHVQEEVISKSSLGHYKNIIRHNGFPAPGTSQHQCPHAPAQGSGR-YVLTKKPVVGFLSLVSSCMLITMCLVIYYAFKRHKLTTKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV98-1", "uniprot_id": "Q9VV98_DROME", "id": "Q9VV98-1", "name": "Cytosolic beta-glucosidase", "aln": "-------------------MMQIILPLFVLT--------------------------------------------ASCLGSPVSQTR-----RFPNDFLWGVGSSSYQIEGGWNADDKGESIWDFLTHTHP---------------EKIVDRSNGDVSADSYHQWKRDVQMVKELHVGTYRFSLSWPRIMPGGYMNHVSTAGIKYYSNLIDELLRYNITPMVTIYHWELPQKLQELGG-WTNPEIIPLFKDYARLVLEMYGDRVKIWTTVNEPWHVCEHGYGVDYMAPSYNYPGIPAYLCGHNLLKAHAEVVHMYRELFQPRQGGRMGITLDTSWPEPRDPNSAEDREASERAMQFYVGWFGHPIFSKHGNYPKVMIERIR--------------------------------------------------------------------------------------------------------------------------------------------------------NLSKEQGFGARSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEFTTEEIHRIRGTSDFFGINSYTSNLVTSNGHNNTGKFPVPSFNHDMGVVESQEGVDWPGSGSVWLKVYPKGMYNLLMWIHREYNAPEIIVTENGVSD-RGGLEDYARVDYYNLYLSAVLDA-MEDGANISGYIAWSLMDSYEWKAGFSEKFGLYHVDFNSPQRTRTPKIS-----ARVFAQLCKTNTIDWSYRPKLDEEQQLVAMAQLPAEARTSGASGAVSWSLMGILLLALLR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * .: **: *:*.**:::*. **.*. ..** **** :*: : ***.:***:: * . :::* * ****:**.*::..* . *:.** .*: * : *:**:***:**: ** * *:* : *:*** : :. :*. ** * *:::*: *. ***... :**. . : .**** *** . ::* ::. ***::.::*.: * * . .:::::* :***.:*:* . :** * :.: :* :.:** .. ** *: :: ::*: **:.:. :*: :* .: :* *: .: * * * * *: : * *:. .* : : **:.: .* * * *:. .*.* : * *: **:*::: * *: * : :. . . : * : . .: :: : : . :: ", "identical_positions": 131, "similar_positions": 155, "identity": "12.3%" }, { "cls_id": "homologset.agr.RGD:620397", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97694-1", "uniprot_id": "CYH1_RAT", "id": "P97694-1", "name": "Cytohesin-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDDDSYVPSDLTAEERQELEN---------------IRRRKQELLADIQR----LKEEIAEVANEIESLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENGLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFSIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNTGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QX11-1", "uniprot_id": "CYH1_MOUSE", "id": "Q9QX11-1", "name": "Cytohesin-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDDDSYVPSDLTAEERQELEN---------------IRRRKQELLADIQR----LKEEIAEVANEIESLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENGLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFSIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNTGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15438-1", "uniprot_id": "CYH1_HUMAN", "id": "Q15438-1", "name": "Cytohesin-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEDDSYVPSDLTAEERQELEN---------------IRRRKQELLADIQR----LKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BHC1-1", "uniprot_id": "A0A8M2BHC1_DANRE", "id": "A0A8M2BHC1-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGTVSELCASSFQAFLCPTVHPAPPAVPDDLTPEEKQELEN---------------IRRRKQELLEDIQR----LKDEITKVTNEIECLGSTQERINMQRSKQMAMGRKKFNMDPKKGIQFLIENELLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPSAERFICMNRGINDGGDLPEDLLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGG-RVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELFIPDNKDQVIKACKTEADGRVVEGNHTFYRISAPTTEEKEDWIKSIKSAISRDPFYEMLAARKKKASSLKRQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E8N2-1", "uniprot_id": "Q0E8N2_DROME", "id": "Q0E8N2-1", "name": "", "aln": "MASLHQKRPSISNWFSSLRRQPKNKKCSPGLGGSESVGRKQPLQRSCLDLSTTRVGCDGCVSLEFFQSESPESRRSNSTFYVNTQNVSSAVFKDNRQPLLERGSGSDSSPSSVCVRCSCNSITKSGDRNETPTMATPKSDIKIALKPPPKPRSPSMAPYTSVATYNITKLAPDSPPPASPTLSTQTVNCSDVTTKVTEVQRLPCDEPNTELISKRTEYKHTTITTTTRTLIVSRPVELLLNENGEIIARRSPRKSRSNSLGRMLDVQNEIGTGGLFMEADPCSKNSLPPPPYIDDMRFIDDSSNSQSESERNSNIHKTNKYTSKNNNNDSKRESQQSNLCESCRMLLDRNYINTEQSDNLVILRRPSKQIKDELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDGNDLMHTFFNPDKEGWLWKQGG-RYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGGAD-IIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQRKKKALSKS--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ...: . :.::* :: *. .:.: * ::* :*:*: :*..*:* *. .:: : ::.**:::*************::*:** **:: :*:*:*******************:::*. :**:*** **:**:* **************************:******* * .:* .*********************.*****:.::**.******:*****. **..*****:.******:****** *******:**** * ** * *:********.***********************:*:**:.* .**:****: ... * :******:::*:****:**.**:**.* *::::*** :. :**::***::*. ****. * . ", "identical_positions": 246, "similar_positions": 107, "identity": "33.65%" }, { "cls_id": "homologset.agr.RGD:620398", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63035-1", "uniprot_id": "CYH2_RAT", "id": "P63035-1", "name": "Cytohesin-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDG------------VYEPPDLTPEE------------------RMELEN--IRRRKQELLVEIQR----LREELSEAMSEVEGLEANEGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVEHELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLSVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEDLLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63034-1", "uniprot_id": "CYH2_MOUSE", "id": "P63034-1", "name": "Cytohesin-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDG------------VYEPPDLTPEE------------------RMELEN--IRRRKQELLVEIQR----LREELSEAMSEVEGLEANEGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVEHELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLSVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEDLLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99418-1", "uniprot_id": "CYH2_HUMAN", "id": "Q99418-1", "name": "Cytohesin-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDG------------VYEPPDLTPEE------------------RMELEN--IRRRKQELLVEIQR----LREELSEAMSEVEGLEANEGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E8N2-1", "uniprot_id": "Q0E8N2_DROME", "id": "Q0E8N2-1", "name": "", "aln": "MASLHQKRPSISNWFSSLRRQPKNKKCSPGLGGSESVGRKQPLQRSCLDLSTTRVGCDGCVSLEFFQSESPESRRSNSTFYVNTQNVSSAVFKDNRQPLLERGSGSDSSPSSVCVRCSCNSITKSGDRNETPTMATPKSDIKIALKPPPKPRSPSMAPYTSVATYNITKLAPDSPPPASPTLSTQTVNCSDVTTKVTEVQRLPCDEPNTELISKRTEYKHTTITTTTRTLIVSRPVELLLNENGEIIARRSPRKSRSNSLGRMLDVQNEIGTGGLFMEADPCSKNSLPPPPYIDDMRFIDDSSNSQSESERNSNIHKTNKYTSKNNNNDSKRESQQSNLCESCRMLLDRNYINTEQSDNLVILRRPSKQIKDELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDGNDLMHTFFNPDKEGWLWKQGG-RYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGG-ADIIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQRKKKALSKS-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*. :::. . *.:: ** *:. *. .:.: ** ::* :::**.*.:**:*.*:. *..* :::::*::*************::***:.**:: *:::*:*******************::::* **:*** **:**:* **************************:****** **.:* .**********:**********.*:*** :::*::******:*****. **..**:***.******:****** *******:**** * ** * *:********.***********************:*:**:.* **:****: ... .::******:::*:****:* ***:**.*:*:::**** : ::* :***::*. ***: *. ", "identical_positions": 248, "similar_positions": 110, "identity": "33.79%" }, { "cls_id": "homologset.agr.RGD:620399", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97696-1", "uniprot_id": "CYH3_RAT", "id": "P97696-1", "name": "Cytohesin-3", "aln": "---------------------------------------------------------------------------------------------------MDEGGGGEGG---------------------------------------------------------------------------------------------------------------------------SVPEDLSLEEREELLDIRRRKKE------------------------------------------LIDD---------------------------------------------IER--------------------LKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08967-1", "uniprot_id": "CYH3_MOUSE", "id": "O08967-1", "name": "Cytohesin-3", "aln": "---------------------------------------------------------------------------------------------------MDEGGGGEGG---------------------------------------------------------------------------------------------------------------------------SVPEDLSLEEREELLDIRRRKKE------------------------------------------LIDD---------------------------------------------IER--------------------LKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGG-RVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43739-1", "uniprot_id": "CYH3_HUMAN", "id": "O43739-1", "name": "Cytohesin-3", "aln": "---------------------------------------------------------------------------------------------------MDEDGGGEGG---------------------------------------------------------------------------------------------------------------------------GVPEDLSLEEREELLDIRRRKKE------------------------------------------LIDD---------------------------------------------IER--------------------LKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E8N2-1", "uniprot_id": "Q0E8N2_DROME", "id": "Q0E8N2-1", "name": "", "aln": "MASLHQKRPSISNWFSSLRRQPKNKKCSPGLGGSESVGRKQPLQRSCLDLSTTRVGCDGCVSLEFFQSESPESRRSNSTFYVNTQNVSSAVFKDNRQPLLERGSGSDSSPSSVCVRCSCNSITKSGDRNETPTMATPKSDIKIALKPPPKPRSPSMAPYTSVATYNITKLAPDSPPPASPTLSTQTVNCSDVTTKVTEVQRLPCDEPNTELISKRTEYKHTTITTTTRTLIVSRPVELLLNENGEIIARRSPRKSRSNSLGRMLDVQNEIGTGGLFMEADPCSKNSLPPPPYIDDMRFIDDSSNSQSESERNSNIHKTNKYTSKNNNNDSKRESQQSNLCESCRMLLDRNYINTEQSDNLVILRRPSKQIKDELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKNDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDKPTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPFKIPQDDGNDLMHTFFNPDKEGWLWKQGG-RYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGG-ADIIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQRKKKALSKS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::...*.:.. . * :* *:*. *:: * :*. :*** ::* :* *:.**::*:: * *:.* ::::**:::*************::*:** **: .*:***:***********.*******:::** .**:*** **:*::* **************************:**.*** **.:* .******************** .*:****.::**:******:*****. **..*****:.******:****** *******:**** * ** * *:********.***********************:*:**:.* **:****: .. .::******:::*:****:*.***:**.: *:::**:* :. ***::****:*. **:: .*.", "identical_positions": 253, "similar_positions": 107, "identity": "34.71%" }, { "cls_id": "homologset.agr.RGD:62040", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20059-1", "uniprot_id": "HEMO_RAT", "id": "P20059-1", "name": "Hemopexin", "aln": "MARTVVALNILVLLGLCWSLAVANPLPAAHETVAKGENGT-------KPDSDVIEHCSDAWSFDATTMDHNGTMLFFKGEFVWRGHSGIRELISERWKNP-----VTSVDAAFR--------GPDSVFLIKEDKVWVYPPEKKENGYPKLFQEEFPGIPYPPDAAVECHRGECQSEGVLFFQGNRKWFWDFATRTQKERSWPAVGNCTAALRWLERYYCFQGNKFLRFNPVTGEVPPRYPLDARDYFISCPGRGHGKLRNGTAHGNSTH--PMHSRCNADPGLSALLSDHRGATYAFSGSHYWRLDSSRDGWHSWPIAHHWPQGPSAVDAAFSWDEKVYLIQGTQVYVFLTKGGNNLVSGYPKRLEKELGSPPGISLDTIDAAFSCPGSSKLYVTSGRRLWWLDLKSGAQATWAELSWP-HEKVDGALCLEKSLGPYSCSSNGPNLFFIHGPNLYCYSSIDKLNAAKSLPQPQKVN-SILGCSQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X72-1", "uniprot_id": "HEMO_MOUSE", "id": "Q91X72-1", "name": "Hemopexin", "aln": "MARTAVALNILVLLGLCWSLAVASPLPTANGRVAEVENGT-------KPDSDVPEHCLDTWSFDAATMDHNGTMLFFKGEFVWRGHSGTRELISARWKNP-----ITSVDAAFR--------GPDSVFLIKEDKVWVYPPEKKENGYPKLFQEEFPGIPYPPDAAVECHRGECQSEGVLFFQGNRKWFWDFATRTQKERSWSTVGNCTAALRWLERYYCFQGNKFLRFNPVTGEVPPRYPLDARDYFVSCPGRGHGRPRNGTAHGNSTH--PMHSRCSPDPGLTALLSDHRGATYAFTGSHYWRLDSSRDGWHSWPIAHHWPQGPSTVDAAFSWDDKVYLIQGTQVYVFLTKGGNNLVSGYPKRLEKELGSPPGISLETIDAAFSCPGSSRLYVSSGRRLWWLDLKSGAQATWTEVSWP-HEKVDGALCLDKSLGPNTCSSNGSSLYFIHGPNLYCYSSIDKLNAAKSLPQPQKVN-SILGCSQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02790-1", "uniprot_id": "HEMO_HUMAN", "id": "P02790-1", "name": "Hemopexin", "aln": "MARVLGAPVALGLWSLCWSLAIATPLPPTSAHGNVAEGET-------KPDPDVTERCSDGWSFDATTLDDNGTMLFFKGEFVWKSHKWDRELISERWKNF-----PSPVDAAFRQ-------GHNSVFLIKGDKVWVYPPEKKEKGYPKLLQDEFPGIPSPLDAAVECHRGECQAEGVLFFQGDREWFWDLATGTMKERSWPAVGNCSSALRWLGRYYCFQGNQFLRFDPVRGEVPPRYPRDVRDYFMPCPGRGHG-HRNGTGHGNSTHHGPEYMRCSPHLVLSALTSDNHGATYAFSGTHYWRLDTSRDGWHSWPIAHQWPQGPSAVDAAFSWEEKLYLVQGTQVYVFLTKGGYTLVSGYPKRLEKEVGTPHGIILDSVDAAFICPGSSRLHIMAGRRLWWLDLKSGAQATWTELPWP-HEKVDGALCMEKSLGPNSCSANGPGLYLIHGPNLYCYSDVEKLNAAKALPQPQNVT-SLLGCTH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKS1-1", "uniprot_id": "A0A8M2BKS1_DANRE", "id": "A0A8M2BKS1-1", "name": "Hemopexin", "aln": "------MAVVFLSLCVCMALSLSHAAPAQH--DVMLKDAP-------EDHH---EDRCKGIEFDAIAPDEKGNTFFFKGDRLWKGLTGASVLSSSVFTELDDYAHLGHVDAAFRMHHEHDASSHDHIYFFLDDKVFSYYNYTLEKGYPMEIQQEFPGVPSHLDAAVECPKGECITDSVLFFKGNEAYSFDIKTKSVKKKVWTHLPNCTSAFRWLEHYYCFHGHNFTRFHPVTGEVTGNYPKDARNYFMRCGEGFG---HGGGAR---------KLRCS-EVKLDAISADERGRMYAFQDVMYVRLDTHRDGSHHFPISRLWKEISGRVDAAFAYGENMYIIQGDQVYIYKSAVHYTLIEGYPKPLKEELG-----IDGPVNAAFLCPQQHTVHIIKDQKMYDVDLVATPR-TAQTVRLIPFADTDAGFCDAE------------GLKVFIGPEYYSYANPTLLAMSRLRPEPRQISPETFGCEE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PHG2-1", "uniprot_id": "HEMO_DANRE", "id": "Q6PHG2-1", "name": "Hemopexin", "aln": "-------MRLIQALSLCLALSLSLAAPPQHKEDHSHKGKPGGEGHKHELHHGAQLDRCKGIEFDAVAVNEEGVPYFFKGDHLFKGFHGKAELSNKTFPELDDHHHLGHVDAAFRMHSEDSPDHHDHQFFFLDNMVFSYFKHKLEKDYPKLISAVFPGIPDHLDAAVECPKPDCPNDTVIFFKGDEIYHFNMHTKKVDEKEFKSMPNCTGAFRYMGHYYCFHGHQFSKFDPMTGEVHGKYPKEARDYFMRCPH-FGSKTTDDHIE---------REQCS-RVHLDAITSDDAGNIYAFRGHHFLSITG--DKFHSDTIESEFKELHSEVDSVFSYDGHFYMIKDNDVFVYKVGKPHTHLEGYPKPLKDVLG-----IEGPVDAAFVCEDHHVVHIIKGQSIYDVDLKATPRKLVKEGTITQFKRIDAAMCGPK------------GVTVVIGNHFYNYDSVQVMLMAKIMPEQQKVSQQLFGCDH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* :*::: . *. :. . : . . .*** : :.:* ****: :::. * . : : ****** : ::: : *: * . *:.** :. ***:* ****** : :* : *:**:*:. : ::: * . .:: : : **:.*:*:: :****:*::* :*.*: *** .** :.*:**: * .. . :*. * *: :*. * *** . : : * * .* : : . **:.*:: :.*:::. :*::: . :.**** *:. :* .::*** * ::: .: :: :** : .: . *..:* : .: .. * . * * . : :: *: :::. . :** .", "identical_positions": 96, "similar_positions": 144, "identity": "19.83%" }, { "cls_id": "homologset.agr.RGD:620400", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIP2-1", "uniprot_id": "MLXPL_RAT", "id": "Q8VIP2-1", "name": "Carbohydrate-responsive element-binding protein", "aln": "---------------MARALADLSVNLQVPRVVPSPDSDSDTDLEDPSPRRSAGG---------LHRSQVIHSGHFMVSSPHSDSLTRRRDQEGPVGLAD---------------------------------------------FGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKIRLNNAIWRAWYIQYVQRRKSPVCGFVTPLQGSEADEHRKPEAVVLEGNYWKRRIEVVMREYHKWRIYYKKRLR-----KSSREGDFLAPKQVEGGWPPPERWCEQLFSSVVPVLLGGSEEEPGGR-----------------QLLDLDCFLSDIS--------------------------------------DTLFTMTQPSPS----------SLQLPSEDAYVGNADMIQPDLTPLQPSLDDFMEISD--------------------------FFTNYRPPQTPTSSNFPEPPSFGPMADSLFSGGILGPEMPSPASASSSSGMTPLSGNTRLQARNSCSGPLDPST-----------FPSSEFLLPEDPKTKMPPAPVPTP------------LLPYPGPVKVHGLEPCTPSPFPTMAPPPALLSEEPLFSARFPFTT-------------------------------------------VPPAPGVSTLPAPTTFVPTPQPGPGPGPVPFPVDHLPHGYLEPVFGPHFTVPQGVQPRCKPCSPPPGGRKASPPTLTSATASPT---------------ATATARDNNPCLTQLLRAAKPEQVLEPSTVPS-----TLLRPPESP-DAVPEIPRVRAFYPPIPAPTPPRPPPGPATLAPPRSLVVPKAERLSPPASSGSERRPSGDLNSIQPPGALSVHLSPPQTVLSRGRVDNNKMENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAAMQEEAQQLRDEIEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASLHSLRQTSLAWLDQYCSLPALRPTVLNSLRQLSTSTSILTDP-SLVPEQATRAVTEGPLGRPL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MZ3-1", "uniprot_id": "MLXPL_MOUSE", "id": "Q99MZ3-1", "name": "Carbohydrate-responsive element-binding protein", "aln": "---------------MARALADLSVNLQVPRVVPSPDSDSDTDLEDPSPRRSAGG---------LHRSQVIHSGHFMVSSPHSDSLTRRRDQEGPVGLAD---------------------------------------------FGPRSIDPTLTHLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKIRLNNAIWRAWYIQYVQRRKSPVCGFVTPLQGSEADEHRKPEAVILEGNYWKRRIEVVMREYHKWRIYYKKRLR-----KSSREGDFLAPKQVEGGWPPPERWCEQLFSSVVPVLLGGSEEEPGGR-----------------QLLDLDCFLSDIS--------------------------------------DTLFTMTQPSPS----------SLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMEISD--------------------------FFTNYRPPQTPTSSNYIESPSFGPMADSLFSSGILAPEMPSPASSSSSSGMTPHSGNTRLQARNSCSGPLDPNP-----------FLSSEFLLPEDPKTKIPPAPGPTP------------LLPFPTPVKVHGLEPCTPSPFPTMAPPPSLLPEESLLSARFPFTS-------------------------------------------APPAPGVSTLPAPTTFVPTPQPGPGP--VPFSVDHLPHGYLEPVFGPHFTVPQGMQPRCKPSSPSPGGQKASPPTLASATASPT---------------ATATARDNNPCLTQLLRAAKPEQALEPPTMPG-----TLLRPPESPQDTVSEIPRARAFFPPIPAPTPPRPPPGPATLAPPRSLVVPKAERLSPPASSGSERRLSGDLNSIQPSGALSVHLSPPQTVLSRGRVDNNKMENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAAMQEEAQQLRDEIEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASLHSLRQTSLAWLEQYCSLPALRPTVLNSLRQLSTSTSILTDP-SLVPEQATRAVTEGTLGRPL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NP71-1", "uniprot_id": "MLXPL_HUMAN", "id": "Q9NP71-1", "name": "Carbohydrate-responsive element-binding protein", "aln": "---------------MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGG---------LLRSQVIHSGHFMVSSPHSDSLPRRRDQEGSVGPSD---------------------------------------------FGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKIRLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMREYHKWRIYYKKRLR-----KPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR-----------------QLLDLNCFLSDIS--------------------------------------DTLFTMTQSGPS----------PLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISD--------------------------FFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPP-----ASSAMTHLSGHSRLQARNSCPGPLDSSA-----------FLSSDFLLPEDPKPRLPPPPVPPP------------LLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPT-------------------------------------------VPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPP-----APSPRGQKASPPTLAPATASPP---------------TTAGS--NNPCLTQLLTAAKPEQALEPPLVSS-----TLLRSPGSPQETVPEFP--CTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAGLQEEAQQLRDEIEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDP-GRIPEQATRAVTEGTLGKPL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VID4-1", "uniprot_id": "Q9VID4_DROME", "id": "Q9VID4-1", "name": "", "aln": "MMLNKHEGYQRTSQMFPHQQHQLPQLHQQPYLQQSLCQNFQQLQYETGVGASASGSAEATADLLKAERESIHSGQFMVSHFEAEEAQDDLEDDGEVKMLDPEDPGLGKPGEPTNTCRDVQLYVPQTVAHFSAMDQEGDESSMSMVTSHLEIETSLTKLFKCMNLAYSQKLTSPKWNHFKGVRLRWKDKIRLNNVIWRCWHMQFIQKRRTPVCQFASPLD---VDIHSNPQTVVLEGKYWKRHSAVIKAEYRKWRRNYRSKATGCLTYDSKSELDFLEWSPLNDRNLMPDDWTTDTLFSAINVPFPFPDSREIARGAGIADFIQPSLGPLQPNLDDIDISFSDLIPTTRLPPVPEEGTDAEMLKNDEYCLSAIVGAPHTLYCNDSIMDVVNSSNNGAVNVDASMLELNTPINNVSYGEVEQRFSVARQVQQSNNDSQLLGDSGSMSGRIHGGKHFGPASANDNNTNRCVINGRVAKSTQRPFRREPHNYDKAQPTMHQTNLYQQMLAEQQKNQQQQHVVVSSFQASQQQQLAQQQPFSAQATNAFNNQSFISSYADNYQHQQQLNVKVEPLHADVLSLLNDNAYNSIGYKPYPQFKKSASTGTFLNVPRQTQQQQSYLQQEPPQMQQSLPVGMGNQQILQLTRQQQVNNTQQQQHQSTVASLLQQQHQQQNHQQQQLQTAVSSATWVSPNTILPKEIYRSNSLPLNVSLNKLPDGRQLHHEQPFAVPKYHSKSKSRVRSNSMHQQHTSVVSAAGAGSSSLGAHSCSNLLVTQQMQQATSDPMLNSTLAQLLTSNSRLQTAVANSSSSNSPSVSAIATTNSNSNAPPVHYANVTSPLSVPVPTHQHSPKKSASLPMAVNSALHSPPLGSKIHGIGLATANVGSNSLSLSPESTFHESQDSPLSPTTSLKFQPRDTQRRAGHIHAEQKRRYNIKNGFDTLHALIPQLQLNPNAKLSKAAMLQKGADHIKQLRQERNVLKDKIEALRMERDELNNSLTHLHSILPANGAPVTRQGTEHVRQLYDIYVRYNTMNDWKFWILGLILEPLLASYTSTVSSASLDELRRTAFLWVDQHCSLIDLRPAVTNKLKYLSMHTDIVSEPPSTLQEEVAKALQNSSGQHPNLHGP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *. * * : * .: : :.. **.* . : ****:**** .::. :::* * * . .*:.:**:**:*:.**** **.****::***::* :*******.***.*::*::::*::*** *.:**: .* * :*::*:***:****: *: **:*** *:.: ... * *:* . :. *: * : : *.: * : .:.. .* :* *:: :**: *::: :.:.. . *: * ::. *:.: . :* * :* :.* . * * .:.. . *. .:. ::.. . :. .. :. * :: * : : *:.... :.:: :: : :: * :* * . . * . . * * . :. :*. .* . :. :* :: *. ... ..:: ** * * . : . :::* : : * :*. :: *. *:*** : . *. . .. : : .. * :: . : . *.** :.* .*:*. . : .. * * *. . . : . . . : . . : :** ** ******:*** ******.*:. *. :*. *:***: *** *::* *:*** :::: : ** * :*** ::. :. ***.*.*:*:* :::*:::* *** .*:::****::.:::.**: *:.. **:**:. **:*:: *::*:*** ***:* *.*: *. *.*:::* . : *:.::*: :.. :* ", "identical_positions": 220, "similar_positions": 296, "identity": "19.61%" }, { "cls_id": "homologset.agr.RGD:620401", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97583-1", "uniprot_id": "BKRB1_RAT", "id": "P97583-1", "name": "B1 bradykinin receptor", "aln": "MAS-EVLLELQPSNRSLQAPANITSCESALEDWDLLYRVLPGFVITICFFGLLGNLLVLSFFLLPWRQWWWQQRQRQQRLTIAEIYLANLAASDLVFVLGLPFWAENIGNRFNWPFGTDLCRVVSGVIKANLFVSIFLVVAISQDRYRLLVYPMTSWGYRRRRQAQATCLLIWVAGGLLSIPTFLLRSVKVVPDLNVSACILLFPHEAWHFARMVELNVLGFLLPVTAIIFFNYHILASLRGQKEASRTRCGGPKGSKTTGLILTLVASFLVCWCPYHFFAFLDFLVQVRVIQDCSWKEITDLGLQLANFFAFVNSCLNPLIYVFAGRLLKTRVLGTL--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61125-1", "uniprot_id": "BKRB1_MOUSE", "id": "Q61125-1", "name": "B1 bradykinin receptor", "aln": "MAS-QASLKLQPSNQSQQAPPNITSCEGAPEAWDLLCRVLPGFVITVCFFGLLGNLLVLSFFLLPWRRWWQQRRQR---LTIAEIYLANLAASDLVFVLGLPFWAENVGNRFNWPFGSDLCRVVSGVIKANLFISIFLVVAISQDRYRLLVYPMTSWGNRRRRQAQVTCLLIWVAGGLLSTPTFLLRSVKVVPDLNISACILLFPHEAWHFVRMVELNVLGFLLPLAAILYFNFHILASLRGQKEASRTRCGGPKDSKTMGLILTLVASFLVCWAPYHFFAFLDFLVQVRVIQDCFWKELTDLGLQLANFFAFVNSCLNPLIYVFAGRLFKTRVLGTL--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46663-1", "uniprot_id": "BKRB1_HUMAN", "id": "P46663-1", "name": "B1 bradykinin receptor", "aln": "MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLLVFLLPRRQ-----------LNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKANLFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRCGGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFFAFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *:**.**:* * * *:*:.* * **** **** *:*::*********:** .**** *: *.:*************************: *:******: ****:.********:**************:**:**:* :*****:.**:****.***** *******::.*****::*****:*******.*:****:******::**::**:******* ::*.******* *.*** .******.:*****.********:**.**:.::.* *::: ************.**.***:****.***::*:* ", "identical_positions": 230, "similar_positions": 67, "identity": "63.19%" }, { "cls_id": "homologset.agr.RGD:620402", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88839-1", "uniprot_id": "ADA15_MOUSE", "id": "O88839-1", "name": "Disintegrin and metalloproteinase domain-containing protein 15", "aln": "---MRLALLWALG------LLGAGSPRPSP----------------PLPNIGGTEEEQQASPERTLSGSMESR---VVQDSPPMSLADVLQTGLPEALRISLELDSESHVLELLQNRDLIPGRPTLVWYQPDGTRMVSEGYSLENCCYRGRVQGHPSSWVSLCACSGIRGLIVLSPERGYTLE------LGPGDLQRP-VISRIQDHLLLGHTCAPSWHASVPTRAGPDLLLEQHHAHRLKRDVVTETKIVELVIVADNSEVRKYP-DFQQLLNRTLEAALLLDTFFQPLNVRVALVGLEAWTQHNLIEMSSNPAVLLDNFLRWRRTDLLPRLPHDSAQLVTVTSFSGPMVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDSPGHSCPCPGPAPAKSCIMEASTDFLPGLNFSNCSRQALEKALLEGMGSCLFER-QPSLAPMSSLCGNMFVDPGEQCDCGFPDECTDPCCDHFTCQLRPGAQCASDGPCCQNCKLHPAGWLCRPPTDDCDLPEFCPGDSSQCPSDIRLGDGEPCASGEAVCMHGRCASYARQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRSPGGSYMPCAPRDVMCGQLQCQWGRSQPLLGSVQDRLSEVLEANGTQLNCSWVDLDLGNDVAQPLLALPGTACGPGLVCIGHRCQPVDLLGAQECRRKCHGHGVCDSSGHCRCEEGWAPPDC-------------MTQLKATSSLTTGLLLSLLLLL----------------VLVLLGASYWHRAR---------------------LHQRLCQLKG--------------SSCQYRAPQSCPPERPGPPQRAQQMT---GTKQASVVSFPVPPSRPLPPNPVP--KKLQAALA-DRSNPPTRPLPADPVVRRPKSQGPTKPPPPRKPLPANPQGQHPPGDLPGP------------GDGSLPLVVPSRPAPPPPAASSLYL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QYV0-1", "uniprot_id": "ADA15_RAT", "id": "Q9QYV0-1", "name": "Disintegrin and metalloproteinase domain-containing protein 15", "aln": "---MRLALLWALG------LLGAGSPRPSP----------------PLPNIGGTEEEQQASPERTQSRSLENQ---VVQDSPPINLTEVLQTGLPETLRIGLELDGENHILELQQNRDLVPGRPTLVWYQPDGTRMVSEGHSLENCCYRGRVQGRPSSWVSLCACSGIRGLVVLSPERSYTLE------LGPGDLQRPLIVSRIQDLLLPGHTCAPSWHAFVPTEAAPDLLLEQHHLRRLKRDVVTETKIVELVIVADNSEVRKYP-DFQQLLNRTLEVALLLDTFFQPLNVRVALVGLEAWTQRDLIEMSSNPAVLLDNFLRWRRTDLLPRLPHDSAQLVTVTSFSGPMVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDSPGNSCPCPGPAPAKSCIMEASTDFLPGLNFSNCSRWALEKALLDGMGSCLFEW-PPSRAPMSSLCGNMFVDPGEQCDCGFPDECTDPCCDYFTCQLRPGAQCASDGPCCQNCKLQPAGWQCRLPTDDCDLPEFCLGDSSQCPPDIRLGDGEPCASGEAVCMHGRCASYTRQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRSPSGSYMPCNLRDAICGQLQCQWGRNQPLLGSVQDQLSEVLEANGTQLNCSWVDLDLGNDVAQPLLALPGTACGPGLVCIGHRCQPVDLLGAQECRSKCHGHGVCDSSRHCHCDEGWAPPDC-------------MTQLRATSSLTTGLLLSLLLLL----------------VLVLLGASYWYRAR---------------------LHQRLCQLKG--------------SSCQYRAAQSGPPERPGPPQRAQQMP---GTKQAN-VSFPVPPSRPLPPNPVP--KKLQAELA-DRSNPPTRPLPADPVVWRPKPQGPTKPPPPRKPLPANPQGRPPLGDLPGP------------GDGSLQLVVPSRPAPPPPAASSLYL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13444-1", "uniprot_id": "ADA15_HUMAN", "id": "Q13444-1", "name": "Disintegrin and metalloproteinase domain-containing protein 15", "aln": "---MRLALLWALG------LLGAGSPLPSW----------------PLPNIGGTEE-QQAESEKAPREPLEPQ---VLQDDLPISLKKVLQTSLPEPLRIKLELDGDSHILELLQNRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQGRVRGYAGSWVSICTCSGLRGLVVLTPERSYTLE------QGPGDLQGPPIISRIQDLHLPGHTCALSWRESVHTQKPPEHPLGQRHIRR-RRDVVTETKTVELVIVADHSEAQKYR-DFQHLLNRTLEVALLLDTFFRPLNVRVALVGLEAWTQRDLVEISPNPAVTLENFLHWRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLPGLNFSNCSRRALEKALLDGMGSCLFER-LPSLPPMAAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTCQLRPGAQCASDGPCCQNCQLRPSGWQCRPTRGDCDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCMHGRCASYAQQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTGRTQPLLGSIRDLLWETIDVNGTELNCSWVHLDLGSDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLGAQECRSKCHGHGVCDSNRHCYCEEGWAPPDC-------------TTQLKATSSLTTGLLLSLLVLL----------------VLVMLGASYWYRAR---------------------LHQRLCQLKG--------------PTCQYRAAQSGPSERPGPPQRALLAR---GTKQASALSFPAPPSRPLPPDPVS--KRLQAELA-DRPNPPTRPLPADPVVRSPKSQGPAKPPPPRKPLPADPQGRCPSGDLPGP------------GAGIPPLVVPSRPAPPPPTVSSLYL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PUF0-1", "uniprot_id": "A0A8M1PUF0_DANRE", "id": "A0A8M1PUF0-1", "name": "", "aln": "MKQHHHQLFRCFWRTLVTILLFEGTPLMMFRGSLTLTLHRNDSSFTPQPDARITHSSHNVTNHRREQKPLAMTRPFAFVDGVRRSLSDVLQKGHPDRLQCGLQVGSSLYILDLEKNQDLLPKPPNVFYYLPNGTGVSMKENTVTHCYYHGSVQGFPESRVALSSCSGLRGVIVINATLSFELLPEGEEERGKDDEGSGEMEEGEMHAIYSTHSPTSESRDCGVSHTSIPPIQIIPHTHRSKRDILSEIKYIELVLVADHKEYLNYQKNNKTIIYRMLDVANQVDWFYRPLNVRVALLGLEIWSDQDKIKVDKSPTETLNRFLDWRTRELLPRLRHDNAQLIMGESFDGTTVGMASQSSMCSKDRSGGVNVDHLVSVLGVASTVAHELGHNLGMSHDTADRRCHCQNEPRLGGCIMEPSTGFMPGQLFSSCSERDLSLSLLHGGGMCLFNVPQPESLLGGPRCGNLYVEKGEECDCGLLDECNDPCCNASTCKLVPGAQCSSDGICCENCKLRVAGSVCREPLGECDLPEHCTGSSPYCPPNVFLQNGEPCKGGSSYCYSGVCASLDDQCQMLWGQNSTRAPPICFSSVNKQGNKYGNCGQMPNGSYIPCLKWDVHCGRIQCQGGGERPLLGSNAEILTTTVILNQSDFTCRGTYFNLGDDVSDPAMVLQGTACGPNKACVDQKCRDVSMFGVDECRSKCHGHGVCNSNKNCHCDEGWAPPDCRYSGNGGSVDSGPAQEPRDSDPARVALLVIFLFVLPVSLLFVALRFPRCRRGLVYLGHTPFNKTRQSRGITVSYIEYCMKEENPRTPAMELANARNGDQAQPLRYQWPHQSDIPLTQAISKVQNRPAAPTKPLPPDPPVSKPAQLAAHWPAPPTKPLPPDPAPSESKMQCKPTGARPAAPSKPLPPDPVLSSRQNPVPPKPPVPKKPLPVDPSCHPPVPPLMGHPVSAAASSSSYSSRNSASAAAPARPAPHPPLRRQQYHGKPHSSHPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 330, "similar_positions": 272, "identity": "33.27%" }, { "cls_id": "homologset.agr.RGD:620403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JK72-1", "uniprot_id": "CCS_RAT", "id": "Q9JK72-1", "name": "Copper chaperone for superoxide dismutase", "aln": "MASKSGDGGTMCALEFTVQMS--CQSCVDAVHKTLKGAAGVQNVEVQLENQMVLVQTTLPSQEVQALLESTGRQAVLKGMGSSQ------LKNLGAAVAIMEGSGTVQGVVRFLQLSSEL---CLIEGTIDGL-EPGLHGLHVHQYGDLTKDCSSCGDHFNPDGASHGGPQD--TDRHRGDLGNVHAEASGRATFRIEDKQLKVWDVIGRSLVVDEGEDDLGRGGHPLSKVTGNSGKRLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGQGRKDSAQPPAHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WU84-1", "uniprot_id": "CCS_MOUSE", "id": "Q9WU84-1", "name": "Copper chaperone for superoxide dismutase", "aln": "MASKSGDGGTVCALEFAVQMS--CQSCVDAVHKTLKGVAGVQNVDVQLENQMVLVQTTLPSQEVQALLESTGRQAVLKGMGSSQ------LQNLGAAVAILEGCGSIQGVVRFLQLSSEL---CLIEGTIDGL-EPGLHGLHVHQYGDLTRDCNSCGDHFNPDGASHGGPQD--TDRHRGDLGNVRAEAGGRATFRIEDKQLKVWDVIGRSLVIDEGEDDLGRGGHPLSKITGNSGKRLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGQGRKDSAQPPAHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14618-1", "uniprot_id": "CCS_HUMAN", "id": "O14618-1", "name": "Copper chaperone for superoxide dismutase", "aln": "MASDSGNQGTLCTLEFAVQMT--CQSCVDAVRKSLQGVAGVQDVEVHLEDQMVLVHTTLPSQEVQALLEGTGRQAVLKGMGSGQ------LQNLGAAVAILGGPGTVQGVVRFLQLTPER---CLIEGTIDGL-EPGLHGLHVHQYGDLTNNCNSCGNHFNPDGASHGGPQD--SDRHRGDLGNVRADADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGRKESAQPPAHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1JH26-1", "uniprot_id": "CCS_DROME", "id": "E1JH26-1", "name": "Copper chaperone for superoxide dismutase", "aln": "MSS--------IKIEFAVQMRRGDESYAGALRSALDGVG---QVEIDTQEGRVIIQTQRPWSEIQDKIEATGVRAVLSGFGGQS------AVALINTTGSVVDKTPIQGVVRFTTITADKKPGVVVDGVVDGL-SPGLHGLHIHESGDTSAGCSSVGEHYNPRQSPHGSPAAGAEERHAGDLGNIRADENGRATFRFVDPVLEVWDIIGRAVVLTANADDLGRGGNDQSLIDGNSGERIACGIIARSAGILENFKRICACDGVTLWDERNKPLAGKERSQKL------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40202-1", "uniprot_id": "CCS1_YEAST", "id": "P40202-1", "name": "Superoxide dismutase 1 copper chaperone", "aln": "MTTN-----DTYEATYAIPMH--CENCVNDIKACLKNVPGINSLNFDIEQQIMSVESSVAPSTIINTLRNCGKDAIIRGAGKPNSSAVAILETFQKYTIDQKKDTAVRGLARIVQVGENK---TLFDITVNGVPEAGNYHASIHEKGDVSKGVESTGKVWHKFDEPIECFNE-------SDLG-----KNLYSGKTFLSAPLPTWQLIGRSFVISKS---LNHPENEPSSVKDYS----FLGVIARSAGVWENNKQVCACTGKTVWEERKDALANNIK----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: ::: * :. .. :: *... .::.. :: : :.: . . : :. * *:: * * . : . .::*:.*: : : :.: .::*: ..* : :*: ** : . .* *. :: . .*** . : : . * .*::***:.:: . *.: : * : . * *:******: :* *::*:* * *:*:** .:*.: : ", "identical_positions": 44, "similar_positions": 93, "identity": "15.28%" }, { "cls_id": "homologset.agr.RGD:620404", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1K9-1", "uniprot_id": "ADA17_RAT", "id": "Q9Z1K9-1", "name": "Disintegrin and metalloproteinase domain-containing protein 17", "aln": "MRQRLLFLTTLVPFVLAPRPPEEPGSGSHLRLEKLDSLLSDYDILSLSNIQQHSIRKRDLQSATHLETL--LTFSALKRHFKLYLTSSTERFSQNLRVVVVDGK-EESEYSVKWQDFFSGHVVGEPDSRVLAHIGDDDVTVRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKDFSRLQ--SPKVCGYLNADSEELLPKGLIDREPSEEFVRRVKRRAE---PNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDN----AGFKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSLDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPGVKKNIYLNSGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLN-NDTCCNSDCTLK--PGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACADTDNSCKVCCRN-LSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHHSNIEMLSSMDSASVRIIKPFPAPQTPGRLQALQPAAMMPPVSAAPKLDHQRMDTIQEDPSTDSHVDDDGFEKDPFPNSSAAAKSFEDLTDHPVTRSEKAASFKLQRQSRVDSKETEC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0F8-1", "uniprot_id": "ADA17_MOUSE", "id": "Q9Z0F8-1", "name": "Disintegrin and metalloproteinase domain-containing protein 17", "aln": "MRRRLLILTTLVPFVLAPRPPEEAGSGSHPRLEKLDSLLSDYDILSLANIQQHSIRKRDLQSATHLETL--LTFSALKRHFKLYLTSSTERFSQNLRVVVVDGK-EESEYSVKWQNFFSGHVVGEPDSRVLAHIGDDDVTVRINTDGAEYNVEPLWRFVNDTKDKRMLVYKSEDIKDFSRLQ--SPKVCGYLNADSEELLPKGLIDREPSEEFVRRVKRRAE---PNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDN----AGFKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPTVKKNIYLNSGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLN-NDTCCNSDCTLK--PGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACVDTDNSCKVCCRN-LSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHHSNIEMLSSMDSASVRIIKPFPAPQTPGRLQALQPAAMMPPVPAAPKLDHQRMDTIQEDPSTDSHADDDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQSRVDSKETEC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78536-1", "uniprot_id": "ADA17_HUMAN", "id": "P78536-1", "name": "Disintegrin and metalloproteinase domain-containing protein 17", "aln": "MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETL--LTFSALKRHFKLYLTSSTERFSQNFKVVVVDGK-NESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQ--SPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRAD---PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDN----AGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLN-NDTCCNSDCTLK--EGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRD-LSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGR---LQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VAC5-1", "uniprot_id": "ADA17_DROME", "id": "Q9VAC5-1", "name": "ADAM 17-like protease", "aln": "------MFTKCISCCGLAIISVFFACLFVENCAALQKTLRHYEIFHKDDVVHRVVKRGAKHSTNPFNTIKEVEFTTLGKNFRLILHPHRDVLHSKFRAYAVDADGNETVVHMDHDSFYSGRVFGELESSVRAHIEDGTMTMSIHLPEETYHIEPSWRHLPEAKKDTMVAYKASDVKVHKNEAGATPKTCGYIKEG-LELEDKEHGDTLDN-ELHTREKRQSDQYEYTPTKTRCPLLLVADYRFFQEMGGGNTKTTINYLISLIDRVHKIYNDTVWQDRSDQEGFKGMGFVIKKIVVHSEPTRLRGGEAHYNMIR-------EKWDVRNLLEVFSREYSHKD--FCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNG--YTLYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPD-IPECSPSASQGGSFLMYTYSVSGYDVNNKKFSPCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVEGDEQCDAGLLGTEDNDSCCDKNCKLRRNQGAMCSDKNSPCCQNCQFMASGMKCREAQYATCEQEARCTGAHAECPKSPAMADGTTCQERGQCRNGKCVPYCET-QGLQSCMCDIIADACKRCCRMSINETCFPVEPPD----VLPDGTPCITGFCNK-GVCEKTIQDVVERFWDIIEEINVAKTLRFLKDNIVMAVVLVTAVFWIPISCVISYFDRK--KLRHEMKLIEWS------------------------------------------------QKLDLI-----------------------------------HPSDERRRVIHIRVPRQKISVARACN-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 284, "similar_positions": 242, "identity": "33.65%" }, { "cls_id": "homologset.agr.RGD:620405", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97776-1", "uniprot_id": "ADA18_RAT", "id": "P97776-1", "name": "Disintegrin and metalloproteinase domain-containing protein 18", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYRKHLKYIGATSPGELCNESYVAGVGTYPEDIGLEGLSMVITQLIGLHIGLTYDD-VDNCSCPRAPCIMQPEALSSSGMKTFSNCSVHDYTHYASKLDMQCLGDLS--NVLQPKQSVCGNGIVEGSEECDCGNETECQFKECCNHETCKLKGSAQCGSGTCCTPKCELSAAGTPCRKAVDPECDFTEYCDGSSSHCVPDTFALDGHLCRLGSAYCYNGRCQALNDQCVSLFGKGSQGASYACFEKVNSQRENLANCDSKNSYSLPCGQKDVLCGKLACFRPNKN-YKSSTQSVLYSYVHGSVCLSIPPGLSMRSDGKDNAYVADGTVCGPQMYCINGSCKEVNFTGNDCNAAKKCKGNGICNNFGHCQCFPDYRPPDCNLQIGSPGGSIDDGNLLRTDSALATKRLSQHADSWVILGFFIFLPFIMTLFLGIIKRNERKIVPQKEQER----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R157-1", "uniprot_id": "ADA18_MOUSE", "id": "Q9R157-1", "name": "Disintegrin and metalloproteinase domain-containing protein 18", "aln": "-MPLLFILAELAMLFARLDSEGICLHITVPQKIEPRKGGDAEGKVTYVITIDGKPYSLHLRNHSFLSQNFLVYTYNETGSLYSDSSHFLAHCHYRGYVDEVPNSIVTLSICSGLRGFLQLENVSYGIEPLESSARFEHIVYQVKSDS---SMLAGNDSHVWQIDQLDKGHFNEQDKNHSQLLPQSLKLHIIVGKFLFDYMGSDIMAITQKIFQIIGLVNAMLTQLKLSVVLASLELWSDKNHISTDGNATDILQRLLDWKRDYLTLQSNEITHLLIYRRRPKYIGAASPGEICSKSYVAGVGMYPEDIGLEGFSVVITQLIGLHIGLTYDDNIRNCSCPSAPCIMQQGALSSSGKKTFSNCSLHDYMHYVSNFDTQCLGDLSNVHVLQPNQAVCGNGIMEAGEECDCGNETECQFKECCDHETCRLKGSAQCGSGACCMPTCELSASGTPCRKAVDPECDFTEYCDGSSSHCVPDTFALNGHLCRLGSAYCYNGRCQALNDQCVSLFGKGSQGASYACFEKVNSPRENLANCDSKDSYSVPCGQQDVLCGKLACFRPPKN-YKSPSQSVVYSYVHDSVCLSILPGLSMRSDGRDSAYVADGTVCGPQMYCINGTCKEVNFTGNDCNATKKCKGNGICNNFGNCQCFPDYRPPDCNLQIGSPGGSIDDGNTLRTESAFATKRLSKNEDSWVILGFFIFLPFIVTFLVGIMKRNERKIVPQGEHKI----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3Q7-1", "uniprot_id": "ADA18_HUMAN", "id": "Q9Y3Q7-1", "name": "Disintegrin and metalloproteinase domain-containing protein 18", "aln": "MFLLLALLTELGRLQAHEGSEGIFLHVTVPRKIKSNDSEVSERKMIYIITIDGQPYTLHLGKQSFLPQNFLVYTYNETGSLHSVSPYFMMHCHYQGYAAEFPNSFVTLSICSGLRGFLQFENISYGIEPVESSARFEHIIYQMKNNDPNVSILAVNYSHIWQKDQPYKVPLNSQIKNLSKLLPQYLEIYIIVEKALYDYMGSEMMAVTQKIVQVIGLVNTMFTQFKLTVILSSLELWSNENQISTSGDADDILQRFLAWKRDYLILRPHDIAYLLVYRKHPKYVGATFPGTVCNKSYDAGIAMYPDAIGLEGFSVIIAQLLGLNVGLTYDD-ITQCFCLRATCIMNHEAVSASGRKIFSNCSMHDYRYFVSKFETKCLQKLSNLQPLHQNQPVCGNGILESNEECDCGNKNECQFKKCCDYNTCKLKGSVKCGSGPCCTSKCELSIAGTPCRKSIDPECDFTEYCNGTSSNCVPDTYALNGRLCKLGTAYCYNGQCQTTDNQCAKIFGKGAQGAPFACFKEVNSLHERSENCGFKNSQPLPCERKDVLCGKLACVQPHKNANKSDAQSTVYSYIQDHVCVSIATGSSMRSDGTDNAYVADGTMCGPEMYCVNKTCRKVHLMGYNCNATTKCKGKGICNNFGNCQCFPGHRPPDCKFQFGSPGGSIDDGNFQKSGDFYTEKGYNTHWNNWFILSFCIFLPFFIVFTTVIFKRNEISKSCNRENAEYNRNSSVVSESDDVGH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**:: **:**: ** :*.:** **:. **: *****:*::*:**:**::****** : :* * *.***: *:*:** * *****:*** ::.*::: :** .** : *: :*.******:*..*******:.*****:**:::**:****.:****.** ..**** :******::**********:*:**:*****:**:*:**:**:******:**: ::**..:****:***.:***::*** :*. **. *:* .:** ::*********.:* ** ** :**.:***::. **:** .* ****** *.*******:***:***:* :*::*:: * :***:.****:*******:*****.:*****::*:*********** :: . : * . : :.*.**.* *****::.: *:**** . : *: ", "identical_positions": 256, "similar_positions": 130, "identity": "34.59%" }, { "cls_id": "homologset.agr.RGD:620407", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2Z2-1", "uniprot_id": "AJUBA_RAT", "id": "Q5U2Z2-1", "name": "LIM domain-containing protein ajuba", "aln": "--MERLGEKASRLLEKLRLSDSGSAKFGRRKGE-ASRSGSDGTPGAGKGRLSGLGGPRKSGHRG----------------------------------------------------ANGGPGDEALEPAREQGPLDAERNARGSFEAQRFEGSFP-----------------------------------------------------GGPPPTRALPLPLSSPPDFRLETT--------------APALSPRSS--FASSSASDASKPSSPRGSLLLDGAGASGAGGSRPCSNRTSGISMGYDQR---------HGSPLPAGPCLFGLPLTTAP------------SGYSSGGVPSAYPELHAALDR-----LCAHRPVGFGCQESRHSYPPALGSPGALTGAVVGTAGPLERRGTQPGRHSVTGYGDCAAGARYQDELTALLRLTVATGGREAGARGEPLGIEPSGLEESPGSFVPEASRSR-------------------IREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGVPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLSARQPPTNYI------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XC0-1", "uniprot_id": "AJUBA_MOUSE", "id": "Q91XC0-1", "name": "LIM domain-containing protein ajuba", "aln": "--MERLGEKASRLLEKLRLSDSGSAKFGRRKGE-ASRSGSDGTPGAGKGRLSGLGGPRKSGHRG----------------------------------------------------ANGGPGDEPLEPAREQGPLDAERNARGSFEAQRFEGSFP-----------------------------------------------------GGPPPTRALPLPLSSPPDFRLETT--------------APALSPRSS--FASSSASDASKPSSPRGSLLLDGAGASGAGGSRPCSNRTSGISMGYDQR---------HGSPLPAGPCLFGLPLTTAP------------AGYP-GGAPSAYPELHAALDR-----LCAHRSVGFGCQESRHSYPPALGSPGALTGAVVGTAGPLERRGAQPGRHSVTGYGDCAAGARYQDELTALLRLTVATGGREAGARGEPSGIEPSGLEESPGPFVPEASRSR-------------------IREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGVPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLSARQPSTNYI------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96IF1-1", "uniprot_id": "AJUBA_HUMAN", "id": "Q96IF1-1", "name": "LIM domain-containing protein ajuba", "aln": "--MERLGEKASRLLEK----------FGRRKGE-SSRSGSDGTPGPGKGRLSGLGGPRKSGPRG----------------------------------------------------ATGGPGDEPLEPAREQGSLDAERNQRGSFEAPRYEGSFP-----------------------------------------------------AGPPPTRALPLPQSLPPDFRLEPT--------------APALSPRSS--FASSSASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQR---------HGSPLPAGPCLFGPPLAGAP------------AGYSPGGVPSAYPELHAALDR-----LYAQRPAGFGCQESRHSYPPALGSPGALAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQDELTALLRLTVGTGGREAGARGEPSGIEPSGLEEPPGPFVPEAARAR-------------------MREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPANYI------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VY77-1", "uniprot_id": "AJUBA_DROME", "id": "Q9VY77-1", "name": "LIM domain-containing protein jub", "aln": "MTTQRTQTQARNPGNSDSDYETLMQRLHIGGGGGAGVGGGGGSGGPGDGGVAMRSYQRSPGAIENYLQESQQQQQQHQMQQMQQLHHNQDYKLYERGNIIAASKYATPRPVEQIQHTHNGSAQIYAPTAQILGQRIAPQKHSPVYENLEFYGQFDSNHKRAQPQSPGSRQSAILNGYLLMQPIRAGRFAHTPVPENQGSASLGTTRAAGGPPPPSGRSAALGPTGDLEEHAAPIYENIIPHSGQRAQPQASPATATMYQEMQPTSNSSGSSSTAGLDLNALLASPMHQRSISSNTASSSSLGSPTQRYRNLSLPSHLSPVPTAQSVAKLQQHTPVKSPGGAINVSVNPNYIEDINSSDYVCMTANLHRNTAAGLATGRAAATGAPAQRTVQEPPIITSSLAMGMATAAP-PTTSNAPTSAAAAPAAPTSTASLRATPIAMTAPLAVATSPTPSQGSTAVNAALKPRRGLTKNLLPYSVTPPRPAGPTEAQRKIEELTRQLEEEIEQSEEHGEYFGICHTCGEKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGHLIMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVEGTDETVRVVSMDKDFHVDCYICEECGMQLTDEPDKRCYPLDGRLLCRGCHLQRLALQSSPHARHQEPVCASYQYMG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :* . :. : * :. .*..*: *.*.* :: . *..* : .*..: .*: * * :: :* .: *.* .****. . . . . . *:. ..: * ** :: : . ..:. *. **. ..* *:. *. .** :*. *:* : * **:*:. .: . ..* . .* * : * *.* * : *... *. .* *.: :.. * ..:. * ... .. : :. . * :** * ::... :..: :. ** : .: ..*. :.:.* : :*** * .*.: : * .:****:..****:**:******:** ****.*:* *******::****::****.:*****:* **************** ***:****:*****..:::***.***: :*****:**: * * ** :: ***:***:*:*.:** **:* ***:** . *:****:***:***:*** :... ", "identical_positions": 189, "similar_positions": 175, "identity": "25.93%" }, { "cls_id": "homologset.agr.RGD:62041", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08625-1", "uniprot_id": "SYT10_RAT", "id": "O08625-1", "name": "Synaptotagmin-10", "aln": "------------------MSFRKEDGVSSLCQKALHIITELCFAGQVEWDKCSGIFPADRSGQGGGGTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKLVAPNVSTLP---------------QSIS------------SAPTEVFETEEKK------EVEENEKPAPKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQTTDPTSSSRHNSFRRHLPRQMNVSSVDFSMGTEPVLQRGETRTSIGRIKPELYKQKSVDSEGNRKDDVKTCGKLNFALQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVVYDQLSNRKLHFSIYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLCIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCSSPRPPSTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0N4-1", "uniprot_id": "SYT10_MOUSE", "id": "Q9R0N4-1", "name": "Synaptotagmin-10", "aln": "------------------MSFRKEDGVSSLCQKALHIITELCFAGQVEWDKCSGIFPADRSGQGGGGTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKLVAPNLSVLP---------------QSIS------------SAPTEVFETEEKK------EVEENEKPAPKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQTTEPTSSSRHNSFRRHLPRQMNVSSVDFSVGTEPILQRGETRTSIGRIKPELYKQKSVDSEGNRKDDVKTCGKLNFALQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVVYDQLSNRKLHFSIYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLCIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCSSPRPPSTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XYQ8-1", "uniprot_id": "SYT10_HUMAN", "id": "Q6XYQ8-1", "name": "Synaptotagmin-10", "aln": "------------------MSFHKEDGVNSLCQKALHIVTELCFAGQVEWEKCSGIFPRDRGSQGGSSTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKPVTSNITTLP---------------QSIS------------SAPTEVFETEEKK------EIKENEKPAVKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQITEPTSSTRHSSFRRHLPRQMQVSSVDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCPSPKPPSTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z5Z8-1", "uniprot_id": "A0A8M6Z5Z8_DANRE", "id": "A0A8M6Z5Z8-1", "name": "", "aln": "MNSRPHASSNIQWINRKDMNVRTEDGIS-LCQRALQIVTELCLAGHVDREKCADIFPLESN-----IPDISVSLLAVVVGFCGLALLVVSLFVFWKLCWPIWRSKAFTSNADSCPPGVLLEAPPAPPPVSRSVSPYAEAKAVGVAGRQPSQIQHEDEEDKKWKVPEVKVNGRSSVKILEAAMKISQTSPDIPAEVQQALRDRLSKQAKIQRQTTEPTSSSRHNSFRRHLPRQMNVTSVDFTMDTLPVRQ--SSAVSIGRIKPELYKQKSVDSEEGTKEPVETCGKLSFALSYDYEEQALVVRILKALDLPAKDFTGTSDPYVKIYLLPERKKKFQTRVHRKTLNPTFDEDFRFPVEYSELCNRKLHFSVYDFDRFTSHDMIGEVVVDNLFELSDLSREAVVWKDILAATTESVDLGEIMYSLCYLPTAGRMTLTVIKCRNLKAMDITGYSDPYVKVALICDGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVEQVSLSITVMDYDRVGHNEVIGVCRAGPDAEGLGRDHWNEMLAYPRKPITHWHALCEWPGRASSFESQGSCPSPKPPQTP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *..:.***:. ***:**:*:****:**:*: :**:.*** : . .***********.******************** *:** .:.* * :*:* *::: . :*:. *:: * :.: * :*.*:***:********** **:::* *:*::*** *:****:**.**********:*:****::.* *: * .: .****************** . :: *: ****.*:*.****:: ***:*:*******************:****:**************** *** *:*** *.:*.*******:******: *******::*****:*******.***** .*****:******:**************************** *******:*:*:*********************************:****.*:*****************:* **************** ********.* * ****:**:*****.**:**.**", "identical_positions": 378, "similar_positions": 98, "identity": "65.85%" }, { "cls_id": "homologset.agr.RGD:620410", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0Q2-1", "uniprot_id": "LT4R1_RAT", "id": "Q9R0Q2-1", "name": "Leukotriene B4 receptor 1", "aln": "MAANTTSTAATSSPGGMSLSLLPIVLLSVALVVGLPGNSFVVWSILKRMQKRSVTALLVLNLALADLAVLLTAPFFLHFLARGTWSFEVTGCRLCHYVCGVSMYASVLLITIMSLDRSLAVARPFVSQKVRTKAFARWVLAGIWVVSFLLAIPVLVYRTVT-PKNKTLICDSRYPSDGHKVFHLLFEAITGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILAFAAFWLPYHLVNLVEAGRTLAGWDKNS-PAGQRLKLARYVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVVKLLEGTGSEVSSTRRGGTLVQTPKATPTCPEPGPTDSFMTSSTPPESSK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88855-1", "uniprot_id": "LT4R1_MOUSE", "id": "O88855-1", "name": "Leukotriene B4 receptor 1", "aln": "MAANTTSPAAPSSPGGMSLSLLPIVLLSVALAVGLPGNSFVVWSILKRMQKRTVTALLVLNLALADLAVLLTAPFFLHFLARGTWSFREMGCRLCHYVCGISMYASVLLITIMSLDRSLAVARPFMSQKVRTKAFARWVLAGIWVVSFLLAIPVLVYRTVK-WNNRTLICAPNYPNKEHKVFHLLFEAITGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILAFAAFWLPYHLVNLVEAGRTVAGWDKNS-PAGQRLRLARYVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVVKLLEGTGSEVSSTRRGGTLVQTPKDTPACPEPGPTDSFMTSSTIPESSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15722-1", "uniprot_id": "LT4R1_HUMAN", "id": "Q15722-1", "name": "Leukotriene B4 receptor 1", "aln": "--MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****.**..* * :***.*:******.********************:****:***********************:***** **********:********** *************:***:****:** *******:***** ***.**** :.. :* ..**.. *:.***:***:*****************************************:*********:***.****::** . .*:** *** *********************************.*********.*******:* **.: *:. ****::*: :**. .. ", "identical_positions": 266, "similar_positions": 50, "identity": "75.14%" }, { "cls_id": "homologset.agr.RGD:620411", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZ76-1", "uniprot_id": "MYG_RAT", "id": "Q9QZ76-1", "name": "Myoglobin", "aln": "MGLSDGEWQMVLNIWGKVEGDLAGHGQEVLISLFKAHPETLEKFDKFKNLKSEEEMKSSEDLKKHGCTVLTALGTILKKKGQ--HAAEIQPLAQSHATKHK---IPVKYLEFISEVIIQVLKKRYSGDFGADAQGAMSKALELFRNDIAAKYKELGFQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04247-1", "uniprot_id": "MYG_MOUSE", "id": "P04247-1", "name": "Myoglobin", "aln": "MGLSDGEWQLVLNVWGKVEADLAGHGQEVLIGLFKTHPETLDKFDKFKNLKSEEDMKGSEDLKKHGCTVLTALGTILKKKGQ--HAAEIQPLAQSHATKHK---IPVKYLEFISEIIIEVLKKRHSGDFGADAQGAMSKALELFRNDIAAKYKELGFQG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02144-1", "uniprot_id": "MYG_HUMAN", "id": "P02144-1", "name": "Myoglobin", "aln": "MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGH--HEAEIKPLAQSHATKHK---IPVKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6VN46-1", "uniprot_id": "MYG_DANRE", "id": "Q6VN46-1", "name": "Myoglobin", "aln": "--MAD--HDLVLKCWGAVEADYAANGGEVLNRLFKEYPDTLKLFPKFSGI-SQGDLAGSPAVAAHGATVLKKLGELLKAKGD--HAALLKPLANTHANIHK---VALNNFRLITEVLVKVMAEKAG--LDAAGQGALRRVMDAVIGDIDGYYKEIGFAG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF15-1", "uniprot_id": "Q9VF15_DROME", "id": "Q9VF15-1", "name": "", "aln": "--MNSDEVQLIKKTWEIPVATPTDSGAAILTQFFNRFPSNLEKFP-FRDV-PLEELSGNARFRAHAGRIIRVFDESIQVLGQDGDLEKLDEIWTKIAVSHIPRTVSKESYNQLKGVILDVLTAACS--LDESQAATWAKLVDHVYGIIFKAIDDDGNAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::: : * . . * :* :*: .*..*. * * : . :: .. . *. :: :. :: *. . :. : . * * :. : . :. ::.*: :. .: : :: . : .: * ", "identical_positions": 14, "similar_positions": 56, "identity": "8.81%" }, { "cls_id": "homologset.agr.RGD:620412", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P0K8-1", "uniprot_id": "PLAK_RAT", "id": "Q6P0K8-1", "name": "Junction plakoglobin", "aln": "-------MEVMN------------LIEQPIKVTEWQQT-YTYDSGIHSGVNTCVPSVSSKGLLDEDDTCGRQYTLKKTTTYTQGVPQSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQTTNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQGLVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLENVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRH----VAAGTQQP--YTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIP------INEPYA-DDMDATYRP------------------------------------------------------------MYSSDVPLDPLDMHMDMDGDYPMDTYSDGLRPPYPAADHMLA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02257-1", "uniprot_id": "PLAK_MOUSE", "id": "Q02257-1", "name": "Junction plakoglobin", "aln": "-------MEVMN------------LIEQPIKVTEWQQT-YTYDSGIHSGVNTCVPSVSSKGIMDEDDACGRQYTLKKTTTYTQGVPQNQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQTTNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQGLVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRH----VAAGTQQP--YTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIP------INEPYA-DDMDATYRP------------------------------------------------------------MYSSDVPLDPLDMHMDLDGDYPMDTYSDGLRPPYPTADHMLA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14923-1", "uniprot_id": "PLAK_HUMAN", "id": "P14923-1", "name": "Junction plakoglobin", "aln": "-------MEVMN------------LMEQPIKVTEWQQT-YTYDSGIHSGANTCVPSVSSKGIMEEDEACGRQYTLKKTTTYTQGVPPSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQATNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRH----VAAGTQQP--YTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIP------INEPYG-DDMDATYRP------------------------------------------------------------MYSSDVPLDPLEMHMDMDGDYPIDTYSDGLRPPYPTADHMLA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9PVF7-1", "uniprot_id": "PLAKA_DANRE", "id": "Q9PVF7-1", "name": "Junction plakoglobin a", "aln": "------MEMHMG------------EAPGSVKVTEWQQSYYGTDSGIHSGATTVR-----------SDDDGTEYSSKK-FTYTTTFTENPAEVESQLNMT-RAQRVRAAMFPETVMEGSVIHSTQIDPSQQTNVQKLAEPSQQLKAAIVHLINYQDDAELATRAIPELTKLLNDEDQLVVNKAAMIVNQLTRKEASRRALMQSPQMVAAVVRAMQNTTDMETTRATASILHNLSHQREGLLAIFKSGGIPALVRMLSSPMDSVLFYAITTLHNLLLHQEGAKMAVRLADGLQRMVPLLKKSNPKFLAITTDCLQLLSYGNQESKLIILANGGPEGLVNIMRTYNYEKLLWTTSRVLKVLSVCPSNKPAIVDAGGMQALGKHLSGSSQRLMQNCLWTLRNLSDAATKQDGMENLLQVLVGLLSADDINMLTCATGVLSNLTCNNTRNKTQVTQSNGVEALIHTILRASSKQDVIEPAVCALRHLTSRHPEAETAQNAVRMHYGIPAIVKLLNQPYHWPVVKAVVGLIRNLALCPANQAPLRDADAIPKLVTLLSKAHQDAQKP----GSS-AQRS--YQDGVRMEEIVEGCTGALHIMARDPMNRGTIASMDTIPLFVQLLYSPLDNVKRVAAGVLCELALDKQSAEIIDAEGASAPLMELLHSSNEGIATYAAAVLYRTAEDKNPDYKKRVSVELTHSLFKHDPEAWEMAHNTV-------MDPVLGDEELDGYGPAGYG---------------------------------------------------------GYADGMHMD--PLDPEMQDDFRSGMPYNSMARVYHDY-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PS81-1", "uniprot_id": "A0A8M9PS81_DANRE", "id": "A0A8M9PS81-1", "name": "", "aln": "------MSLQMS------------EADGAVKVEEWQQSFYTADSGIQSGATTIR-----------DED---ESESRK-YSAG----ESSADMEAQFSLT-RAQRVRAAMFPETLVEGETVLTPQSNPDQPTNVQRLAEPSQLLKTAIVHLINYQDDAELATRAVPELTKLLADDDQVVVNKAALIVNQLTRKEASRRVLMQSPQMVSAVVRAMQNTGDLETARCAASVLHSLSHQREGLLAIFKSGGIPALVRMLSSPMESVLFYAITTLHNLLLHQEGAKMAVRLADGLQRMVPLLKKTNPKFLAITTDCLQLLSYGNQESKLIILANGGPECLVFIMRNYNYEKLLWTTSRVLKVLSVCPSNKPAIVDSGGMQALGQHLTGSSQRLTQNCLWTLRNLSDAATKQEGLDGLLQILVSQLGSDDVNMLTCATGILSNLTCNNARNKALVTQSGGVEALIHAVLRAGEKEDVAEPAVCALRHLTSRHPDAELAQNAVRLHYGIPAITKLLGQPHYWPVVKATVGLIRNLALCPANQAPLRESGAIPRLVNLLLKAHQETQRH----GSG-AQQT--YQDGVRMEEIVEGCTGALHILARDPMNRGEIASMQTIPLFVQLLYSYVENIKRVSAGVLCELALDKQSAEMIDAEGASAPLMELLHSPNEGIATYAAAVLFRISEDKSSDYRKRVSVELTHSLFKHDPAAWDMAHAAMP------LDPGYIPDDLDVVYPP-YG----------------------------------------------------------YSD-LPMDGLPLEAELHEQYMPEMAYDPRQ-VYPNPL------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18824-1", "uniprot_id": "ARM_DROME", "id": "P18824-1", "name": "Armadillo segment polarity protein", "aln": "MSYMPAQNRTMSHNNQYNPPDLPPMVSAKEQTLMWQQNSYLGDSGIHSGAVTQVPSLSGK---EDEEMEGDPLMFDLDTGFPQNFTQDQVDDMNQQLSQTRSQRVRAAMFPETLEEGIEIPSTQFDPQQPTAVQRLSEPSQMLKHAVVNLINYQDDAELATRAIPELIKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVAALVRAISNSNDLESTKAAVGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQDGSKMAVRLAGGLQKMVTLLQRNNVKFLAIVTDCLQILAYGNQESKLIILASGGPNELVRIMRSYDYEKLLWTTSRVLKVLSVCSSNKPAIVDAGGMQALAMHLGNMSPRLVQNCLWTLRNLSDAATKVEGLEALLQSLVQVLGSTDVNVVTCAAGILSNLTCNNQRNKATVCQVGGVDALVRTIINAGDREEITEPAVCALRHLTSRHVDSELAQNAVRLNYGLSVIVKLLHPPSRWPLIKAVIGLIRNLALCPANHAPLREHGAIHHLVRLLMRAFQDTERQRSSIATTGSQQPSAYADGVRMEEIVEGTVGALHILARESHNRALIRQQSVIPIFVRLLFNEIENIQRVAAGVLCELAADKEGAEIIEQEGATGPLTDLLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSIELTNSLLREDNNIWANADLGMGPDLQDMLGPEEAYEGLYGQGPPSVHSSHGGRAFHQQGYDTLPIDSMQGLEISSPVGGGGAGGAPGNGGAVGGASGGGGNIGAIPPSGAPTSPYSMDMDVGEIDAGALNFDLDAMPTPPNDNNNLAAWYDTDC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. :. ***. * ****:**. * .: . : * *::*** ** * . *. : . * * :*:*:**** ** *:*:**************:*** *** *:* :**.:**::*:**::*****:.:* ***:*:*:**::.*: *:::::.:.. **.***:*:***************::****::***************:*:*:*******.***:**.**::.* *****.*****:*:************.***: ** ***.*.******************.*******::******. ** . * ** ************.*** :*:: :*: ** *. *:*::***:* ******** :**: * * .**:**:::::.*..:::: ************** ::* ***:**::**:..*.*** * **::**.:************:***:: .* :** ** :*.*:::: : :*:. * *********** .*****:**:. ** * ..**:**:**:. ::*::**:******** **:.*: *: ***:.** :**** *** ********:* :*** **:**:*:***:**::.* * *. : :. : : . .. . :. :: : ", "identical_positions": 379, "similar_positions": 179, "identity": "44.8%" }, { "cls_id": "homologset.agr.RGD:620413", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70467-1", "uniprot_id": "ANM3_RAT", "id": "O70467-1", "name": "Protein arginine N-methyltransferase 3", "aln": "MCSLAAGN--GQGAELGPEPL-ELSDSGDDAGWEDEDADAEPAQ-GRQHTPCLFCDRLFRSAEETFSHCKLEHQFNIDGMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWDKDEYLKPVLEDDLLLQFDVEDLYEPVSAPFTYPNGLSENTSAVEKLKLMEARALSAEAALARAREDLQKMKQFAQDFVMNVDVR-TCSS-TTTIADLQEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEWMGYFLLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKAVIPEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTIFLLEKPFPVKAGEALKGKITVHKNKKDPRSLIVTLTLNSSTQTYSLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922H1-1", "uniprot_id": "ANM3_MOUSE", "id": "Q922H1-1", "name": "Protein arginine N-methyltransferase 3", "aln": "MCSLAAGN--GRGAELGPEPL-ELSDSGDDAGWEDEDADTEPAH-GRQHTPCLFCDRLFASAEETFSHCKLEHQFNIDSMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWEKDEYLKPVLEDDLLLQFDVEDLYEPVSTPFSYPNGLSESASVVEKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMNVDVR-TCSS-TTTIADLQEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKVGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEWMGYFLLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKAVIPEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFPVKAGEALKGKITVHKNKKDPRSLIVTLTLNSSTQTYSLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60678-1", "uniprot_id": "ANM3_HUMAN", "id": "O60678-1", "name": "Protein arginine N-methyltransferase 3", "aln": "MCSLASGATGGRGAVENEEDLPELSDSGDEAAWEDED-DADLPH-GKQQTPCLFCNRLFTSAEETFSHCKSEHQFNIDSMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWEKEEYLKPVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVVEKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMHTDVR-TCSSSTSVIADLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVIPEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTLTLNNSTQTYGLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFB3-1", "uniprot_id": "Q9VFB3_DROME", "id": "Q9VFB3-1", "name": "type I protein arginine methyltransferase", "aln": "MKDTEVNDNTTEEEPVKEAPEVPANSSSDEDEYDDIDDDDEPMDEGDELTTCLFCTETSANISVAIDHLDARHKVNLSQLQRKFEMDQYSFIKLINYIRAKKISAEQLLSAEHPL-WQDEKYLQPG-EYEPWLCYDYEVLKT---------DGAPTQPSVLELQQRIAEQSQ----LLQQANEDMERMRNDYKALLQKVHADGEPKGSDQSVPRNNVCLDNEYFKSYAHFGIHHEMLSDKVRTSTYRASLLQNEAVVRGKTVLDVGCGTGILSIFASKAGAARVVGIDNSDIVYTAMDIIRKNKVEN-VELIKGRLEDTDLPETKYDIIISEWMGYFLLYESMLDSIIYARENHLNPNGIILPSRCTLSLLGYGDDTLYADEVEFWSNVYEVDMSDLRKQSIEEPLMQVVDAEFMLTEPEQIANFDIMTVDMNYPNFTHQFSLKVTKPGRLSAFVGYFETLFELPSP--VMFSTSPSATPTHWKQTVFFIENPQVVKEGDVICGKITSRRHKEDVRGLSVDIEVFGKKHKYNVV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . . ..*.*: ::* * * : . * : *.**** . . . ::.* . .*:.*:. : :*. :: *.:*****:** *: :.* : * :*: *:.::**:* * : * :* * * :* . ..*.:* : : :: * :*.**:::*:: : :: :... .. :. : *. **.**.*:***.***.**:**.:** : ** :.:.*.************:**:*.** :*:.:*:*:*:* ****** **:*: : ****::*:. ** * *:***********:******::**:.::* .* : *. **:**:. .* . :**.: **.:** ..** ::* * *.:::*:* : ::::* * ::* *..:. :*: :*:*: *:.. :*..***: ** . *:***.*.:* ******:*::*:* ** *:.: **:* :::*:* *.* * : : ...:.*.: ", "identical_positions": 187, "similar_positions": 187, "identity": "35.02%" }, { "cls_id": "homologset.agr.RGD:620416", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35303-1", "uniprot_id": "DNM1L_RAT", "id": "O35303-1", "name": "Dynamin-1-like protein", "aln": "---MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGVVTRRPLILQLVHVSP------EDKRKTTGEENDPATWKNSR-------HLSKGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISGNNKGVSPEPIHLKVFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKK--YPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYG----EPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVS---RDKSSKVPSALAPASQEPSPAASAEADGKLIQDNRRETKNVASAGGGIGDGGRIGDGGQEPTTGNWRG-MLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLL-DVPVP-VARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1M6-12", "uniprot_id": "DNM1L_MOUSE", "id": "Q8K1M6-12", "name": "Dynamin-1-like protein", "aln": "---MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGVVTRRPLILQLVHVSP------EDKRKTTGEEN--------------------GVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISGNNKGVSPEPIHLKVFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKK--YPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYG----EPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAGS---RDKSSKVPSALAPASQEPPPAASAEADGKLIQDNRRETKNVPSAGGGIGDGG------QEPTTGNWRG-MLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLL-DVPVP-VARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00429-1", "uniprot_id": "DNM1L_HUMAN", "id": "O00429-1", "name": "Dynamin-1-like protein", "aln": "---MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTRRPLILQLVHVSQ------EDKRKTTGEEN--------------------GVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKK--YPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYG----EPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVS---RDKSSKVPSALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGV------QEPTTGNWRG-MLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLL-DVPVP-VARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SXN5-1", "uniprot_id": "DNM1L_DANRE", "id": "Q7SXN5-1", "name": "Dynamin-1-like protein", "aln": "---MEALIPVINKLQDVFNTVGADIIQLPQIAVVGTQSSGKSSVLESLVGRDLLPRGTGIVTRRPLILQLVHVDP------EDRRKTS-EEN--------------------GVDGEEWGKFLHTKNKIYTDFDEIRQEIENETERVSGNNKGISDEPIHLKIFSPHVVNLTLVDLPGITKVPVGDQPKDIELQIRELILKYISNPNSIILAVTAANTDMATSEALKVAREVDPDGRRTLAVVTKLDLMDAGTDAMDVLMGRVIPVKLGLIGVVNRSQLDINNKKSVADSIRDEHGFLQKK--YPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLSAQYQSLLSSYG----EPVEDMSATLLQLITKFATEYCNTIEGTAKYIETAELCGGARICYIFHETFGRTLESVDPLGGLTTIDVLTAIRNATGPRPALFVPEVSFELLVKRQVKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTSLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRMR-ELPTSVP---RDK----------------MAGGAQAE-------------------------------QEGGTGTWRG-MLK--KGDEGQGEEKTKLQSSIPASPQKGHAVNLL-DVPVP-VARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDSLQSELVGQLYKPALLDDLLTESEDMAQRRNEAADMLKALQKASQVIAEIRETHLW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQE0-1", "uniprot_id": "Q9VQE0_DROME", "id": "Q9VQE0-1", "name": "dynamin GTPase", "aln": "---MEALIPVINKLQDVFNTVGSDSIQLPQIVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLVLQLIYSPL------DDRENRSAENG--------------------TSNAEEWGRFLHTK-KCFTDFDEIRKEIENETERAAGSNKGICPEPINLKIFSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYIENPNSIILAVTAANTDMATSEALKLAKDVDPDGRRTLAVVTKLDLMDAGTDAIDILCGRVIPVKLGIIGVMNRSQKDIMDQKHIDDQMKDEAAFLQRK--YPTLATRNGTPYLAKTLNRLLMHHIRDCLPDLKTRVNIMATQFQSLLNSYG----EDVSDKSQTLLQIITKFSSAYCCTIEGTARNIETTELCGGARMGYIFHETFGRTLDSIHPLAGLSKMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEEPSLRCVELIHEEMQRIVQHCGNEVQQEMLRFPKLHEKIVDVVTQLLRRRLPHTNVMVENIVAIELAYINTKHPDFHKDAALVPSLLKTDSDPYSQINLGQRRANTPRNHMSPQISSHSAGSQQPQQQQPPQPNSSQQQYSQVHEQNHVAENS------------TPSMASTWLSNILPPAPTRPDSIENSTNNTPVHNNIVSPVKPVNLLPDVPANHNPRRLTDKEQKDCDVIEHLIKSYFYIVRKSIQDSVPKAIMHFLVNYVKDNLQSELVTHLYKSDKAETLLNESDHIAVRRKEAADMLKALTRANHIISEIRETHMW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54861-1", "uniprot_id": "DNM1_YEAST", "id": "P54861-1", "name": "Dynamin-related protein DNM1", "aln": "MASLEDLIPTVNKLQDVMYDSGIDTLDLPILAVVGSQSSGKSSILETLVGRDFLPRGTGIVTRRPLVLQLNNISPNSPLIEEDDNSVNPHDEVTKISGFEAGTKPLEYRGKERNHADEWGEFLHIPGKRFYDFDDIKREIENETARIAGKDKGISKIPINLKVFSPHVLNLTLVDLPGITKVPIGEQPPDIEKQIKNLILDYIATPNCLILAVSPANVDLVNSESLKLAREVDPQGKRTIGVITKLDLMDSGTNALDILSGKMYPLKLGFVGVVNRSQQDIQLNKTVEESLDKEEDYFRKHPVYRTISTKCGTRYLAKLLNQTLLSHIRDKLPDIKTKLNTLISQTEQELARYGGVGATTNESRASLVLQLMNKFSTNFISSIDGTSSDINTKELCGGARIYYIYNNVFGNSLKSIDPTSNLSVLDVRTAIRNSTGPRPTLFVPELAFDLLVKPQIKLLLEPSQRCVELVYEELMKICHKCG---SAELARYPKLKSMLIEVISELLRERLQPTRSYVESLIDIHRAYINTNHPNFLSATEAMDDIMKTRRK-RNQELLKSKLS----QQENGQTNGINGTSSISSNIDQDSAKNSDYDDDGIDAESKQTKDKFLN--------YFFGKDKKGQPVFDASDKKRSIAGDGNIEDFRNLQISDFSLGDIDDLENAEPP-----LTEREELECELIKRLIVSYFDIIREMIEDQVPKAVMCLLVNYCKDSVQNRLVTKLYKETLFEELLVEDQTLAQDRELCVKSLGVYKKAATLISNIL-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ***.:******: * * ::** :.*:*:*******::*::***.:******:******:*** :* .. . .: ..:***.*** * : ***:*::****** * :*.:**:. **:**:**.:*:*********:****:*:** *** **::*:* :* .**.:****:.**.*:..**:**::::***:*:**:.*:*******:**:*:*:* *:: *:***::**:**** ** :* : :.: .* ::::: * :::.: ** ***: **: *: **** **::**::* : :* :. * ** .. : :**::.**:: : :*:**: *:* *******: **:::.**.:*.*:.* ..*. :*: *****:*****:*****::*:**** *:: * *** *****::**: :* ::*. *: *:***:. :::*:: ***.** *. *..:: *. *****:**:* . : . :: * . :: ... . : : . : :: * :. *: :*: :*::*::** *** *:*: *:*.****:* :***: **.:*..** :*** : ** *.: :* *: ... * . * :*::* ", "identical_positions": 285, "similar_positions": 218, "identity": "36.4%" }, { "cls_id": "homologset.agr.RGD:620417", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKC8-1", "uniprot_id": "AP3M1_MOUSE", "id": "Q9JKC8-1", "name": "AP-3 complex subunit mu-1", "aln": "MIHSLFLINCSGDIFLEKHWKSVVS---------QSVCDYFFEAQEKAADVENVPP-VISTPHHYLISIYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFG--ECSEAAIKDNVVIVYELLEEMLDNGFPLATES---NILKELIKPPTILRSVVNSITGSSNVGDTLPT--------GQLSN-----------IPWRRA-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVFAEIQGVIDACIKLSGMPDLSLSFMNP-RLLDDVSFHPCIRFKR-WESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFK-------ENSSCGRFDITIGPKQNMGKTIEGITVTVHMPKVVLNMN----------LTPTQGSYTFDPVTKVLAWDVGKITPQ-KLPSLKGLVNLQSGAP---KPEENPNLNIQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGVKYVTKAGKFQVRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53676-1", "uniprot_id": "AP3M1_RAT", "id": "P53676-1", "name": "AP-3 complex subunit mu-1", "aln": "MIHSLFLINCSGDIFLEKHWKSVVS---------QSVCDYFFEAQEKAADVENVPT-VISTPHHYLISIYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFG--ECSEAAIKDNVVIVYELLEEMLDNGFPLATES---NILKELIKPPTILRSVVNSITGSSNVGDTLPT--------GQLSN-----------IPWRRA-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVFAEIQGVIDACIKLSGMPDLSLSFMNP-RLLDDVSFHPCIRFKR-WESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHNISFK-------ENSSCGRFDITIGPKQNMGKTIEGITVTVHMPKVVLNMN----------LTPTQGSYTFDPVTKVLAWDVGKITPQ-KLPSLKGLVNLQSGAP---KPEENPNLNIQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGVKYITKAGKFQVRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2T2-1", "uniprot_id": "AP3M1_HUMAN", "id": "Q9Y2T2-1", "name": "AP-3 complex subunit mu-1", "aln": "MIHSLFLINCSGDIFLEKHWKSVVS---------QSVCDYFFEAQEKAADVENVPP-VISTPHHYLISIYRDKLFFVSVIQTEVPPLFVIEFLHRVADTFQDYFG--ECSEAAIKDNVVIVYELLEEMLDNGFPLATES---NILKELIKPPTILRSVVNSITGSSNVGDTLPT--------GQLSN-----------IPWRRA-GVKYTNNEAYFDVVEEIDAIIDKSGS---TVFAEIQGVIDACIKLSGMPDLSLSFMNP-RLLDDVSFHPCIRFKR-WESERVLSFIPPDGNFRLISYRVSSQNLVAIPVYVKHSISFK-------ENSSCGRFDITIGPKQNMGKTIEGITVTVHMPKVVLNMN----------LTPTQGSYTFDPVTKVLTWDVGKITPQ-KLPSLKGLVNLQSGAP---KPEENPSLNIQFKIQQLAISGLKVNRLDMYG-----EKYKPFKGVKYVTKAGKFQVRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76928-1", "uniprot_id": "O76928_DROME", "id": "O76928-1", "name": "", "aln": "MIHSLFIVNSGGEVFLEKHWRSVVS---------RSVCEYFLDAQRAAP--YDVPP-VIATPHYYLITVQRDTVSLVAACKQEVPPLFVIEFLHRVVDTFQDYFG--DCSESVIKDNYVVVYELLDEMLDNGFPLATES---NILKELIKPPNILRTIANTVTGKSNVSTTLPS--------GQLSA-----------VRWRRS-GVRYTNNEAYFDVIEEVDAIIDKSGS---TVFAEIQGHIDCCIKLSGMPDLTLSFMNP-RLFDDVSFHPCVRYKR-WEAERLLSFIPPDGNFRLMSYHISSQSVVAIPIYIRHNFSIK-------TGE-QGRLDLTIGPRNTLGRTVDKVKLELTMPRCVLNCL----------LTPNQGKYTFDSVTKTLSWDVGRIDVS-KLPNIRGSVSITPGTT---NIDANPSVNVQFQISQLAVSGLKVNRLDMYG-----EKYKPFKGVKYLTKAGKFQVRM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38153-1", "uniprot_id": "AP3M_YEAST", "id": "P38153-1", "name": "AP-3 complex subunit mu", "aln": "MYLSFYITDTKNKLIFQYLLGATAPSFKHLWTRVQSTCPQLLEDSSSDDYLDHSMVGRDLEVYKYFSVINKLNYWCLASTSKSKGPLDCFTFLETIDRILLEYFDKDKLSIKKIVNNYDRISLIFNCCVEAGEPNVSDMLYVNKIKEAVPERSDLSKFISSTAHNLQQAVQLPQQRQQQLQQNQISRGSNSLIENEEIVPWRTSRASKHENNELYVDLLETFHVVFEKKKSHLRLLTGSIHGIVDVRSYLNDNPLVAVKLNTMGNDIGIPSLHDCVEINDGVFSPSNITFIPPDGKFRLLEYSVDLSSQVKQSGVRMNSIGLMSLHFQNGLGKDSDEFELSLN-IENFKKVSQVDDLKIDLQFNVENADPNEIAYKIKILRNTHGRFENSIIMGQGQWIFDKSTATGTVPVLRGCIEYENTGPNFTKKVDLQTVSLEYSYIGQSASGIYVEAIDIVSGLTIGKNTKLYKGAKYKTQTGNFQVRL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *::: : ..:::: :... :*.* ::: . . : *: : : . :: . . ** : **. : : :**. . * * :* : ::: :: * * .:: * :** : . * .. .: : . : . ** .*:* : ** : . :: *** *.*::* ...:::*. * : ..*:* :* *.. * :::.: . . :. *:* *:. : : ::******:***:.* :. .. * . :.:.: .. ..:::::. :.: :. : : : : * * * .:* : . : * ..: .:* ::* :. . : .:.:::. : **: *: :*: . :: * :**.** *::*:**** ", "identical_positions": 75, "similar_positions": 166, "identity": "15.5%" }, { "cls_id": "homologset.agr.RGD:620418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923V4-1", "uniprot_id": "FBX6_RAT", "id": "Q923V4-1", "name": "F-box only protein 6", "aln": "-----------------------------------------------MVNINELPENILLELFTHVPAPQLLRNCRLVCSLWRDLIDVMTLWKRKSLREGFVTKDRDEPVDDWKIFYILCSLQRNLLRNPCAEENLRSWRIDSNGGDEWKVESLPGDHGTSFPDTKVKKYFVTSYGMCLKSQMVDLKAEGYSEKLLDTVRPDIVVKDWFAPRADCGCTYHLRVQLASADYIVLASFEPPPVTIEQWNDASWQEISHTFSNYPPGVRHILFQHGGKDTQFWKGWYGPRVTNSSIIVSHRTAKNPAPARTLPEE-----------DTSNRRKILSFGSWEDLSP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZN4-1", "uniprot_id": "FBX6_MOUSE", "id": "Q9QZN4-1", "name": "F-box only protein 6", "aln": "-----------------------------------------------MVHINELPENILLELFIHIPAPQLLRNCRLVCRLWRDLIDVVSLWKRKSLREGFFTKDRCEPVEDWKVFYILCSLQRNLLRNPCAEENLSSWRIDSNGGDRWKVETLPGSCGTSFPDNKVKKYFVTSFEMCLKSQMVDLKAEGYCEELMDTFRPDIVVKDWVAPRADCGCTYQLRVQLASADYIVLASFEPPPVTFQQWNDAKWQEISHTFSDYPPGVRHILFQHGGQDTQFWKGWYGPRVTNSSIIISHRTAKNPPPARTLPEETVVIGRRRRASDSNTHEGFFWQGLWQRLRR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRD1-1", "uniprot_id": "FBX6_HUMAN", "id": "Q9NRD1-1", "name": "F-box only protein 6", "aln": "--------------------------------------MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAHGTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCTYQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQYWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQ-------------KHGQEEAAQSPYRAVVQIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IKA2-1", "uniprot_id": "A0AC58IKA2_DANRE", "id": "A0AC58IKA2-1", "name": "", "aln": "MSKSESRHFDSASKEFGHRSDVTWIYKLTLFQRCTFRHDDVIAKGRFSGVMPAVPLAVVEEILLNLPAHQVVRVCRLVCPEWKELVDSAAHWRERCRREGIQPCDASRPPKNWCQFYFITKKRRNLIKNPAADDEFQGWEILENGGNGWEIE----NNRKPFPDNTVTKCFTTSCWLCLKQQLIDLEKEGYNAAFMDQLQPHIKISDWYAPCQDCGSEYNINVELLDDQMKQISDFQPEVVVFEWPNKEPWCQTTHVFKNYGPGVRFIRFTHGGKDTRFWAGNYGIRITNSSVEICPAAEI-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* :: *:: ::** *:: ***** *::*:* : *:.:. ***: . * .* :* **:: . :***::**.*:::: .*.* ***: *::* . *** .*.* *.** :***.*::** *** ::* .:*.* :.** *. ***. *::.*:* . : ::.*:* *.:: *. * : ::.*.:* ***.* * ***:**::* * ** *:****: :. ", "identical_positions": 90, "similar_positions": 83, "identity": "26.16%" }, { "cls_id": "homologset.agr.RGD:620419", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2P8-1", "uniprot_id": "VAMP5_MOUSE", "id": "Q9Z2P8-1", "name": "Vesicle-associated membrane protein 5", "aln": "MAGKELKQCQQQADEVTEIMLNNFDKVLERHGKLAELEQRSDQLLDMSSAFSKTTKTLAQQKRWENIRCRVYLGLAVAVGLLIILIVLLVVFLPSGGDSSKP--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z2J5-1", "uniprot_id": "VAMP5_RAT", "id": "Q9Z2J5-1", "name": "Vesicle-associated membrane protein 5", "aln": "MAGKELERCQRQADQVTEIMLNNFDKVLERDGKLSELQQRSDQLLDMSSAFSKTTKTLAQQKRWENIRCRVYLGLAVAGGLLLILVVLLVIFLPSGEDSSKP--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95183-1", "uniprot_id": "VAMP5_HUMAN", "id": "O95183-1", "name": "Vesicle-associated membrane protein 5", "aln": "MAGIELERCQQQANEVTEIMRNNFGKVLERGVKLAELQQRSDQLLDMSSTFNKTTQNLAQKKCWENIRYRICVGLVVVGVLLIILIVLLVVFLPQSSDSSSAPRTQDAGIASGPGN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **::**:**::***** ***.***** **:**:***********:*.***:.***:* ***** *: :**.*. **:**:****:***.. ***.. ", "identical_positions": 68, "similar_positions": 24, "identity": "58.62%" }, { "cls_id": "homologset.agr.RGD:62042", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08835-1", "uniprot_id": "SYT11_RAT", "id": "O08835-1", "name": "Synaptotagmin-11", "aln": "MAEITNIRPSFDVSPVAAGLIGASVLVVCVSVTVFVWTCCHQQAEKKHKTPPYKFIHMLKGISIYPETLSNKKKIIKVRRDKDGSHRESGRGNLLVN-AESGLLSHDRDPRGPSPASCIDQLPIKRDYGEELRSPMTSLTPGESKPTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDGQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTTSGAEHWREVCESPRKPVAKWHSLSEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0N3-1", "uniprot_id": "SYT11_MOUSE", "id": "Q9R0N3-1", "name": "Synaptotagmin-11", "aln": "MAEITNIRPSFDVSPVAAGLIGASVLVVCVSVTVFVWTCCHQQAEKKHKTPPYKFIHMLKGISIYPETLSNKKKIIKVRRDKDGPRRESGRGNLLIN-AESGLLSHDKDPRGPSPASCMDQLPIKRDYGEELRSPMTSLTPGESKATSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPVFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTTSGAEHWREVCESPRKPIAKWHSLSEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BT88-1", "uniprot_id": "SYT11_HUMAN", "id": "Q9BT88-1", "name": "Synaptotagmin-11", "aln": "MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLKGISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSEY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************.********************:*********:*.**********************************. **.** ***:: **:****:*:******..**:****** *********:*********.******************************************.************************************************************************************************************************************************************************:**********************************************:****************:*********", "identical_positions": 407, "similar_positions": 20, "identity": "94.43%" }, { "cls_id": "homologset.agr.RGD:620420", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91XU7-1", "uniprot_id": "CDHR1_RAT", "id": "Q91XU7-1", "name": "Cadherin-related family member 1", "aln": "-------------------------MRRGPQVA----LVLGLLCIYLAQANFAPHFFDNGVGSTNGNMALFSLPED--TPVGSHVYTLNGTDPEGDPISYH--ISFDPSTRSVFSVDPNFGNITLVEELDREREDEIEAIISISDG------LNLVAEKVVIVVTDANDEAPRFLQEPYNILVPENTPAG---SSIFKVQAEDKDTGSGGSVTYFLQS-------LHSSKFTVDRHSGVLRLQAGATLDYEKSRAHFITVVAKDGGGRLRGADVVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNE-------------SDGLFEINETSGAISVLQSPAQLRREVYELHVQVTEVNSSGSPAAQSTVPVIIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGANAKFNLRLVGPG---GIFRVVPQTVLNEAQVTIIVENSAAIDFEKSK-SLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENVPGGSNVVAVTAVDPDTGPWG--KVQYS-IYGTGSDLFLIHPSTGLIYTQPWASLDAE--GTSRYNFYVKAED--MDGRYSLAEVFVTLLDVNDHYPQFVQSVQEKTMVLGTPLKIEATDQDAEEP------NNLVDYSITRAE--PVNVFDIDAHTGEIRLKNSIRSLEALHN------------------------------------------------------------------------------------------------------------------------ITPSGEYSWSLQVQAKDRGSPS------------------------------------------------------------FSTTALLKIDITDTERLSRSSMAAFLIQTKDNPMKAVGVLAGVMAIVVAITVLISTATFWRNKKS-----------NKVLPVRRVLRRRPSPAPHTVRIEWLKFRRAKAASKFILKEDPPNENCNNSRVGVTVPPRAPALPPPP-----------------------KMASST-VAQQTVPTVSGSLTPQPSQQLPTPKPLGGPAQSSLVS---ELKQKFEKKSLGNKAYV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHP6-1", "uniprot_id": "CDHR1_MOUSE", "id": "Q8VHP6-1", "name": "Cadherin-related family member 1", "aln": "-------------------------MRRGPRVA----LVLGLLRIYLAQANFAPHFFDNGVGSTNGNMALFSLPED--TPVGSHVYTLNGTDPEGDPISYH--ISFDPSTRSVFSVDPNFGNITLVEELDREREDEIEAIISISDG------LNLVAEKVVILVTDANDEAPRFIQEPYIIRVPENIPAG---SSIFKVQAEDKDTGSGGSVTYSLQN-------LHSSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNE-------------SDGIFEINETSGAISVLQSPALLRREVYELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGANAKFNLRLVGPG---GIFRVVPQTVLNEAQVTIIVENSAAIDFEKSK-LLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWG--KVHYS-IYGTGSDLFLIHPSTGLIYTQPWASLDAE--GTSRYNFYVKAED--MDGRYSLAEVFVTLLDVNDHYPQFVQSVQEKTMVLGTPLKIEATDQDAEEP------NNLVDYSITRAE--PVNVFDIDAHTGEIRLKNSIRSLEALHN------------------------------------------------------------------------------------------------------------------------ITPSGDYSWSLQVQAKDRGSPS------------------------------------------------------------FSTTALLKIDITDTERLSRGSMAAFLIQTKDNPMKAVGVLAGVMAIVVAITVLISTATFWRNKKS-----------NKVLPVRRVLRRRPSPAPHTVRIEWLKFRRAKAATKFILKEDSPNENCNNSRVGVMVPPRAPALPPPP-----------------------KMASSM-VAQQTVPTVSGSLTPQPSPQLPTPKTLGGPVQSSLVS---ELKQKFEKKSLDNKAYI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JP9-1", "uniprot_id": "CDHR1_HUMAN", "id": "Q96JP9-1", "name": "Cadherin-related family member 1", "aln": "-------------------------MRRCRWAA----LALGLLRLCLAQANFAPHFFDNGVGSTNGNMALFSLPED--TPVGSHVYTLNGTDPEGDPISYH--ISFDPSTRSVFSVDPTFGNITLVEELDREREDEIEAIISISDG------LNLVAEKVVILVTDANDEAPRFIQEPYVALVPEDIPAG---SIIFKVHAVDRDTGSGGSVTYFLQN-------LHS-PFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKDGGGRLHGADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLKVVAMDGDRGKPNRILYSLVNG-------------NDGAFEINETSGAISITQSPAQLQREVYELHVQVTEMSPAGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGANAKFNLQLVGPR---GIFRVVPQTVLNEAQVTIIVENSAAIDFEKSK-VLTFKLLAVEVNTPEKFSSTADVVIQLLDTNDNVPKFDSLYYVARIPENAPGGSSVVAVTAVDPDTGPWG--EVKYS-TYGTGADLFLIHPSTGLIYTQPWASLDAE--ATARYNFYVKAED--MEGKYSVAEVFITLLDVNDHPPQFGKSVQKKTMVLGTPVKIEAIDEDAEEP------NNLVDYSITHAE--PANVFDINSHTGEIWLKNSIRSLDALHN------------------------------------------------------------------------------------------------------------------------ITPGRDCLWSLEVQAKDRGSPS------------------------------------------------------------FSTTALLKIDITDAETLSRSPMAAFLIQTKDNPMKAVGVLAGTMATVVAITVLISTATFWRNKKS-----------NKVLPMRRVLRKRPSPAPRTIRIEWLKSKSTKAATKFMLKEKPPNENCNNNSPESSLLPRAPALPPPP-----------------------SVAPSTGAAQWTVPTVSGSLTPQPTQPPPKPKTMGSPVQSTLIS---ELKQKFEKKSVHNKAYF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6B3P0-1", "uniprot_id": "CDHR1_DANRE", "id": "Q6B3P0-1", "name": "Cadherin-related family member 1a", "aln": "-------------------------MKNAREIQFSSFLLLAHFCFVGAQSDYAPYFYDNGPNSNNGNMALLNLSED--TPRGTQIYVLNGTDPEGQPVKYG--ITFEPGSKEFFRVHPKSGVVTLIEDLDREAQDEIEVFVSISDS------LNKVVEKVSVFIMDANDERPQFQNMPSIVDVPENTTSG---SSIYKVQAVDRDTGSGGSVTYFLQSS------EQSPKFAIDHHSGVLRIKPGESLDYEKSRTHFITVVAKDGGGIYKGKQQVMSSSATLTINVIDTQDSPPIFIGTPYFGYVYEVSSPGSEIFTVSAKDGDMDNPNTIIYSLDSG-------------ADGSFSINKTSGVITLNLYPADLRREVFNIKVKALEISPEGKRLDFATTTVTIRVVDLNNHPPTFYGENGPQNVFELTMYEHPQEGEFLRGLKITVNDSDQGSNAKFNLRLVGPG---RMLRVVPQTVLNEAQVTVLVEDSAAMDFEKSQ-FLTFKLLAVEIDTPERFSATADIIIHLLDTNDNAPKFTSDFYIARIPENSPGGSNVVSVTAMDPDSGIWG--VVKYS-IYGSGADIFLIQADSGIIYTQPWASLDAE--VKSKYNFYVKAED--PEGKYSLAEVFVTITDLNDHPPAFNENSLEQTMVIGAPVKIEAIDEDAEEP------NNLIEYSIMKAD--PDNIFDINADTGEIKLKPYIKSMDIVQN------------------------------------------------------------------------------------------------------------------------ITNQRDCTWSVVVQAKDRGSPS------------------------------------------------------------FSTTTVVKIDITEATPL-KGPLTSFFMNSRENPMHFLGLISGVILILVFVTVIISTVIFVRRNKA-----------NRILPSRRIIRKKRKPQKQDDFQEPFREEQEIPRADNVNFNNN-IKVCSHRTPPS--PPNAPVMPPPL-----------------------PSHCRHGEREWTVPTVSASVASKSKKK--SHRCKDNPVNTALVS---ELKLKLEQKNMANRY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVG0-1", "uniprot_id": "Q9VVG0_DROME", "id": "Q9VVG0-1", "name": "", "aln": "-------------------------------------MLPLLLPLFLSLTAGQLVNQPPQFVPGTGDMSRFSLSEN--TPVGSPVFQLKGTDPEGGRLKYS--ISG-----PVFSVDRETGVVRLRQELDRETQDTVEVIISITDEGIYGTEPNTVSQRRVIPVRDYNDNQPTFLGRPYTASVSESLPVGSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIFEVRAVKISDGNYTARVALKQQLDFESRPSYILTISASDS-----ALDNRLSSLATISINVIDIQDQPPIFTNAPYSATVPENTPAGVSILTVKAVDGDVGIPREIFLSLEDEPFGHFELVPFGDPRDGTAVLQTTSEPLDRENAEILQNGGVYVFSIRATELIDGAIPAEHSLTRVTIVVTDVDDHQPTFSG-----PHFNVSITENLANGMPLPGLSIFVDDRDMGENSRYELSLRDVFNAARVFEVSPTESQGRTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASVKGVEKAKTRVEIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFG--HVRYV-LKGFGADNFYVNPETGGVY--LLKPLDYE--KQSSYSLTVVAID--GGQREANANLFVGVTDVNDNHPNFESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKYSIVSENSIAGNVFRIEPDTGEIVIQKAARSMDTERGEYELVVSAT---------DFGIPPLSNTTRVLVRVGISGNQRPIFRGHFQNMENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPDGLDSLLRYRIVGANDNFEIDEISGLITVSPQARIDRDSNMNSFEIIVNAVDSGTPIPETATTTVYVNVKDINDERPKFEQNSYATYVSERTAVGESVLRVKAIDKDLNSKLEYSMVGPVAATTKAGVSIANRSNYRLQEAFRVDSQSGEIFVNGTLRHDVAAIIIFTVGVRDLNAEVDPEGQVDTTEVTVYVQSFQDTNPVFKNTGWTSSRPVIDVKIKEEMPIDSALFILQAEDPVTRQPITSFELIEPKQVDYFQVAERTGEVILKKRLDYEALGDTGPEFELQVRANSADRQRSTVSRVNITVENVNDNSPRFERNSYQATIIENRPHPERVIRVRALDKDAVLNARDERLGYHKIIYSLQGEHAMLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAEDSPGRPTDAKQS---VVELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGLGGEVRYELVNEGEANGLFKIDTKSGLISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQPTLSTDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDDESTPSGTITYRILPDTP-DAEAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQPKQSA-TRILQIAILDVDDHEPRFAREADAGPLSMS----VREEEPAGTIVGNFSALDEDLGENAAIDYVIIDGNNEQLFTIERNNESLAILKTKKPIDREQVESFTLTIKCLK-------------------------------------------------------------------LGEPGYKFIGDPYDRQDLSHLRINVRVLDIDDNLPKFEQPDPTVGIRINVPIDTVVTTLKASDADAEAPPVGLSIENVTFVPQFYKRSRSLAVGNLHNLFTLNNRTGELRTGGSFADYVDGYFLMRVMANNSVQPKRQAHSNLKVFVIRDKSLLKFVFARPPNEIQHNIRPFQEQLQKKLKPLGLELHVLDTQVFTRPDMSLDFTATSSCFQMFKNGAALSFNEMQKLMNSQQLRQELIDIYAAYGVSEVESCSVRRTHAAAIFAGMLTSAGAWLVFLAALIGLAALVSLCTACCLKKKLKRHSKRSLQASLRTPTEHTATSYSYSMPAVLYSEPIYGPL----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFH5-1", "uniprot_id": "Q9VFH5_DROME", "id": "Q9VFH5-1", "name": "", "aln": "MHNESQPPANGNGIDSMDYKKVRLKGQRRRSFSSYISSISIQVIILTTLISLVASNRPPRFAIDGQSEIVLRLKESPETKVGTLIYTLKGYDPDNDPLTFGKRNSHDSEIIRIENTGGNEAKIFLAKELDRELQDEYAIVLTLTDS--HYSDHNYVTQSFLLLVEDINDNVPTFLPYQNAIEIPEGSAPG----VVSTLEATDADEGAYGQVVYYLQELD-----GDNDVFSIATHQGKGILRLQKELDYERKSLYQLRVLAIDR----ANQGPINTGTAAILVKVKDLEDQPPEFVEVQAVARIAEDAPVGTKVLRVRAIDGDRGINNPIAYSLEAN--------DLFDINPHTGIVHTLTKLDREEQSDQVNGAHILRISATELSKSNTQMAPTTVRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQTNTPLN-FIDEEVQNVVFDHDEGNNGTFRLFLDPPN---DLFEIVPELAVNEANFMLRVKNSKSLDFEQFT-EVNFTIFAREVDEPSRWSS-AHVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTIITHVQAVDVDSGDYGTMGIRYTNLRGGIAHLLNLNPITGVITIKQAGGTAFDREIISRHYLTVEAIDNAGQGNRNTAQIIVDILDVNDNAPTFPQRQYETKLLENQAEFETPLQLEARDADLNGTENSQVTYEIVEGLY--RSNFTIDPQSGLLRPVHSFDFEELVDGSSRRSDPYTGGSFSIREIDLLVRARDSGIPMLSTVVPVLIYVQDVNDNAPIFQQSFYAKTVPEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQTGAGDKFIINSETGVISVAHGANLDPDLTESKRSLYTLSVIALDGGLGNSQLMTTCTVNISIQDVNNKPPVLKEMPALQILENTPVGTLVYRIQATDLDHKAILRYKLNPEHCEGRTEEGALVKSSEYDFLGAFEVDSIEGTLKVVKLLDRERVEHIKLAITVEDLAAAKGRQIA----------EGFLSIQVLDENDNNPKFRLPFYRQSITENSINGAMIVNVLASDVDKNRTITYALEGNPTYRSLMHLDPQTG-----------EIVVASKIDHEQHQWLNFSVRATDSGIPARSSLVDVYITVLDENDNNPYFVGGSKNYTISENAAPGTRVATLQAGDADSGDFGKITFLMDRISSQGKFTIDADTGVLTVADRLDRESKDSYNLVIEAWDNYQFGFLAGESRNAFKQVFISILDENDNPPEVDLPMSCVLITEYHELHERVASIVGKDADDPTTPNGRLDFAITRGNKDGMFELRQIDAWNAQIFASKSLRNRYGNYSLTITTRDMGLPANIVHN-----TLDICVSDFNDHAPVFVRPLHNTTVRIPENATVGTLILQAYASDGDMGQN--ALVRYRLKPDPLGSYKMFEVDGSTGELFLKEQLNREKQKIHEIRIEAYDQGLPTSLSSDLDLTIYVRNVNDYEPQFMVNEISVNFTEHSDPGSERIKLPDTIDKDQLELDDPNDTPSQVCYFIVNGNEAGYFRLDPETHILTVDR---ELDREVIANFTLYVRATENCRNDSISGGEKRRRMGIEINNRLGGIVHNQQFGYDRFKHSRQLRSTESNEYGPEDAELLSYEAYDSSQEDPTGGLATTHPELDSTVIKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLKFMRVEATDADEGDN----GRIGYYQVGEIRQTLSEGLENVRKAPFLLDQETGEVQLNFDPQKGMKGYFDFVVLAN--DTSGMKDVAHVFIYLLREDQKVRFVFRLQPDELRSRVDSFRDTLSN---ITESIVNIDEIKVHENKDGSVDKTKTDLYMHLVEREDNSIYEVSEVLKLIDSHIESLNGLFKELNVLDTQAAEAQLLTAGPSRGPLFVWLIFTNLFLATLLVVTIALCASQRNGYRRQLRAAKVNIFRGHSSMSLQDAQEPATRVPNTNKHSVQGSNPIWLKGYDNEWFKSEESGSIGGHDSLDDNFLAVATQDMHETLKGTAKLFNNSNDLNRHFNLYNQIDKMTNNAQILARKLETTEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . : * *. * *: :: *:* **:. :.: : . . . : * ::**** :* .::::* * * : : : * **: * * :.*. . * : . * * * ..* . . . : . : **:* : : : * * :. ::: ::* * :* .* * . . : * : * .:: * * *** . . * * :: : : : . . * : : *:::. *** : : : : :. * * * * *. :.* * ::.: * ..: . : * :: :*:: : : . .: : : * : * *** * * . * ** .: : * * * *:* :* ::* * :. : ::. :* : : : : : * * * . *:::: : *:**: * * . . .: . . *.:. *. : *.* . * *:..:* : : . : : * * * * . : . :* ::: .. : : : .:: : : : . . : .. . : . : : : .* * . :. :: . . . ", "identical_positions": 104, "similar_positions": 200, "identity": "5.07%" }, { "cls_id": "homologset.agr.RGD:620421", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70404-1", "uniprot_id": "VAMP8_MOUSE", "id": "O70404-1", "name": "Vesicle-associated membrane protein 8", "aln": "-----------MEEASGSA-----GNDRVRNLQSEVEGVKNIMTQNVERILSRGENLDHLRNKTEDLEATSEHFKTTSQKVARKFWWKNVKMIVIICVIVLIIVILIILFATGTIPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WUF4-1", "uniprot_id": "VAMP8_RAT", "id": "Q9WUF4-1", "name": "Vesicle-associated membrane protein 8", "aln": "------------MEASGSA-----GNDRVRNLQSEVEGVKNIMTQNVERILARGENLDHLRNKTEDLEATSEHFKTTSQKVARKFWWKNVKMIVIICVIVLIILILIILFATGTIPT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BV40-1", "uniprot_id": "VAMP8_HUMAN", "id": "Q9BV40-1", "name": "Vesicle-associated membrane protein 8", "aln": "-----------MEEASEGG-----GNDRVRNLQSEVEGVKNIMTQNVERILARGENLEHLRNKTEDLEATSEHFKTTSQKVARKFWWKNVKMIVLICVIVFIIILFIVLFATGAFS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P31109-1", "uniprot_id": "SNC1_YEAST", "id": "P31109-1", "name": "Synaptobrevin homolog 1", "aln": "MSSSTPFDPYALSEHDEERPQNVQSKSRTAELQAEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAVSAQGFKRGANRVRKAMWYKDLKMKMCLALVIIILLVVIIVPIAVHFSR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P33328-1", "uniprot_id": "SNC2_YEAST", "id": "P33328-1", "name": "Synaptobrevin homolog 2", "aln": "MSSSVPYDPYVPPEESNSG-ANPNSQNKTAALRQEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAISAQGFKRGANRVRKQMWWKDLKMRMCLFLVVIILLVVIIVPIVVHFS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:.:. *: *::.. .** :*:::: ***.* :.:*:::* ::: ** :::* : :*:*::** : : ::::*:::.*:: . :. ", "identical_positions": 21, "similar_positions": 50, "identity": "17.95%" }, { "cls_id": "homologset.agr.RGD:620423", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54715-1", "uniprot_id": "VAS1_RAT", "id": "O54715-1", "name": "V-type proton ATPase subunit S1", "aln": "MMAATVVSRIRTGTRWAPVLWLL------LSLVAVAAAVAAEQQVPLVLWSSDRDLWAPVADTHEGHITSDMQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNLENALDLAPSSLVLPAVDWYAISTLTTYLQEKLGASPLHVDLATLKELKLNASLPALLLIRLPYTASSGLMAPREVLTGNDEVIGQVLSTLESEDVPYTAALTAVRPSRVARDVAMVAGGLGRQLLQTQVASPAIHPPVSYNDTAPRILFWAQNFSVAYKDEWKDLTSLTFGVENLNLTGSFWNDSFAMLSLTYEP-LFGATVTFKFILASRFYPVSARYWFTMERLEIHSNGSVAHFNVSQVTGPSIYSFHCEYVSSLSKKGSLLVTN-VPSLWQMTLHNFQIQAFNVTGEQFSYASDCAGFFSPGIWMGLLTTLFMLFIFTYGLHMILSLKTMDRFDDRKGPTITLTQIV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1Q9-1", "uniprot_id": "VAS1_MOUSE", "id": "Q9R1Q9-1", "name": "V-type proton ATPase subunit S1", "aln": "MMAATVVSRIRTGTGRAPVMWLS------LSLVAVAAAVATEQQVPLVLWSSDRNLWAPVADTHEGHITSDMQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNLENALDLAPSSLVLPAVDWYAISTLTTYLQEKLGASPLHVDLATLKELKLNASLPALLLIRLPYTASSGLMAPREVLTGNDEVIGQVLSTLKSEDVPYTAALTAVRPSRVARDITMVAGGLGRQLLQTQVASPAIHPPVSYNDTAPRILFWAQNFSVAYKDEWKDLTSLTFGVENLNLTGSFWNDSFAMLSLTYEP-LFGATVTFKFILASRFYPVSARYWFAMERLEIHSNGSVAHFNVSQVTGPSIYSFHCEYVSSVSKKGNLLVTN-VPSVWQMTLHNFQIQAFNVTGEQFSYASDCAGFFSPGIWMGLLTTLFMLFIFTYGLHMILSLKTMDRFDDHKGPTITLTQIV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15904-1", "uniprot_id": "VAS1_HUMAN", "id": "Q15904-1", "name": "V-type proton ATPase subunit S1", "aln": "MMAAMATARVRMGPRCAQALWRMPWLPVFLSLAAAAAAAAAEQQVPLVLWSSDRDLWAPAADTHEGHITSDLQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNLENALDLAPSSLVLPAVDWYAVSTLTTYLQEKLGASPLHVDLATLRELKLNASLPALLLIRLPYTASSGLMAPREVLTGNDEVIGQVLSTLKSEDVPYTAALTAVRPSRVARDVAVVAGGLGRQLLQKQPVSPVIHPPVSYNDTAPRILFWAQNFSVAYKDQWEDLTPLTFGVQELNLTGSFWNDSFARLSLTYER-LFGTTVTFKFILANRLYPVSARHWFTMERLEVHSNGSVAYFNASQVTGPSIYSFHCEYVSSLSKKGSLLVARTQPSPWQMMLQDFQIQAFNVMGEQFSYASDCASFFSPGIWMGLLTSLFMLFIFTYGLHMILSLKTMDRFDDHKGPTISLTQIV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7JR49-1", "uniprot_id": "VAS1_DROME", "id": "Q7JR49-1", "name": "V-type proton ATPase subunit S1", "aln": "-------------MLWKS------------LIALCVIGAAVAEQTPVFLWGAN--------SVAKPSLKTVSQVEFAEQLAALLEDHMVVAFEENGLSSKDFLCS----NSQAQSCYAQLQG----------VSPKTYYTSVENPSEALRSVAAKREHNSIDASGKLTTPAKCAVGTALFVTFEDAA--ESREASLESHDAAIAAISKQFECKVAYLYLAAPSTAPVVQRRTRRDTAATTGGIMWKSTNQFQIFYTALLYNGNP-------------------------ITVTDLKLT----NSSSTKLSVVMDTSVADKPITFDVVYNG--------GYFSLSNLVYDNN----NFRSSGVNAPTTFSYSCGNLTLESAAVNNMYNT---LSFKSLQLQAPFDGTYKEDFPFGDSWDCVGFVTPGILMGLFVVALLLVIMFVGVCWMMDINTMDRFDDPKGKTITINAAAE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . ..*. :*.*:.**.:: .. : :.: *:. : * * : *: * :: ** :** . ..: :*.:::*:. :.. :*: .: ..:.*. * .: : :*. *. .. : :.: :: : . * .:* .*. : . ::.: . * .:. * * .*. * : :. ::..: **... : * :*:** *.* : **:. : : . .:**..: . :*::..* ..* *. * *..*: :*: * :: * . : :: : ::. . *. : **..*.:*** ***:. ::*.*: *: ::.::******* ** **::. . ", "identical_positions": 75, "similar_positions": 155, "identity": "15.89%" }, { "cls_id": "homologset.agr.RGD:620424", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63644-1", "uniprot_id": "ROCK1_RAT", "id": "Q63644-1", "name": "Rho-associated protein kinase 1", "aln": "-----------MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLP--SANPSENRS-SSNVDKNVQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDK----IMKELDEEGNQRRNLESAVSQIEKEKMLLQHRINEYQRKVEQENEKRRNVENEVSTLKDQLEDLRKASQSSQLANEKLTQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSVSQLESLNRELQERNRMLENSKSQADKDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSIQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVETEKQCSMLDVDLKQSQQKLEHLTENKERLEDAVKSLTLQLEQESNKRILLQSELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNR---ENLRKIQELQSEKETLSTQLDLAETKAESEQLARGILEEQYFELTQE-------SKKAASRNRQEITDKDHTVSRLEEANNALTKDIELLRKENEELNERMRTAEEEYKLKKEEEISNLKAAFEKNISTERTLKTQAVNKLAEIMNRKDFKIDRKKA---NTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQLASKESDIEQLRAKLLDLS---DSTSVASFPSADETDGNLPVGSACIPYLFIFYSSSSRIEGWLSVPNRGNIKR-YGWKKQYVVVSSKKMLFYNDEQDKE-QSSPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRK-----DIEVEPVQ---QGEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALECRRCHVKSHRDHLDKKEDLIPPCKVSYDVTSARDMLLLACPQDEQKKWVTHLVKKIPKKAPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70335-1", "uniprot_id": "ROCK1_MOUSE", "id": "P70335-1", "name": "Rho-associated protein kinase 1", "aln": "-----------MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLP--SANASENRS-SSNVDKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNLKLDK----IMKELDEEGNQRRNLESAVSQIEKEKMLLQHRINEYQRKVEQENEKRRNIENEVSTLKDQLEDLRKASQTSQLANEKLTQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQADKDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSIQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVETEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLALQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNR---ENLRKIQELQSEKETLSTQLDLAETKAESEQLARGILEEQYFELTQE-------SKKAASRNRQEITDKDHTVSRLEETNSVLTKDIEMLRKENEELNERMRTAEEEYKLKKEEEINNLKAAFEKNISTERTLKTQAVNKLAEIMNRKDFKIDRKKA---NTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQLASKESDIEQLRAKLLDLS---DSTSVASFPSADETDGNLPE---------------SRIEGWLSVPNRGNIKR-YGWKKQYVVVSSKKILFYNDEQDKE-QSSPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRK-----DIEVEPVQ---QGEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13464-1", "uniprot_id": "ROCK1_HUMAN", "id": "Q13464-1", "name": "Rho-associated protein kinase 1", "aln": "-----------MSTGDSFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSNRRYLS--SANPNDNRT-SSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDK----IMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNR---ENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQE-------SKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKA---NTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKLLDLS---DSTSVASFPSADETDGNLPE---------------SRIEGWLSVPNRGNIKR-YGWKKQYVVVSSKKILFYNDEQDKE-QSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRK-----DVEMEPVQ---QAEKTNFQNHKGHEFIPTLYHFPANCDACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLICPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PRV2-1", "uniprot_id": "A0A8M9PRV2_DANRE", "id": "A0A8M9PRV2-1", "name": "Rho-associated protein kinase", "aln": "---------MEMSIGESLTARFEKIDAMLKDPKSEVNTDCLLDSLDALVYDLDFPALRKNKSIDDFLKRYKDTISKIRELRMKAEDYEVVKVIGRGAFGEVQLVRHKATRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSNWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDGIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKDGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNALTFPEDSDISKDAKSLICAFLTDREVRLGRNGVDEIKRHGFFKNDQWTWENIRETAAPVVPELSCDTDTSNFDDIEEDRGEEETFPIPKAFVGNQLPFVGFTYYSNNLFSQESTIKTSDKRS-STKEDKSLLENLQKRIYQLEEQVHSEMQLRDEMEQKCRASNTKLDK----IMKELDEESNLRKSVEANMSILEKDKIMIQHRATEYQRKADQEAEKRRNLENEVSTLKEQLEDLRKISQN----NDKIAQLQNQLGEANDLLRAESDTVMRLRKSHTEMGKTMSQLESINRELQEKIRAAESVKQQLEKELLQLQTTLDTERRSCSQGSEEIRELQVRIMGLQEDNKNLKQSLTKVETERKHVQERCNILEKEKNSLEIDLNYKLKTLQQRLDQELTEHRITKAQLTDKYESIEESKSAAMHAVEQKVSEETTLRMRAESRVVEVEKQCSMLEFDLKQSVQKMEQLMKQKERLEDEVKDLRVQLEQETGKRVMSQNELKNWKMDSERLKGTEKQLKQEINAALENKRSVEFQLAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKDEIEEKNRQTQEALKRVQDLNSEKESLSAQLDLTMTKAESEQLARALQEEQYVELSQE-------YKKAVSRYKQEISEKDSTISQLEDSNKTLTKDVEILSKEKTEFNERIQAQEQEFAAEREELTNSIKANYEKALNIERTLKTQAVNKLAEIMNRKDMKDQKKRG---STTDLRKKEKENRKLQLELNQEKEKFNHMAFKYQKELNEMQAQWAEECTYRNELQMQLDSKESDIEQLREKLNDLQLRVDNSSVTSLQ-PDELDSNIAE---------------SRLEGWLAIPNRANIKR-YGWKKQYVVVSSKKILFYNDEQDKE-QSNPSMVLDIDKLFHVRPVTQGDVYRAETDEIPRIFQILYANEGECRK-----ETDVESVP---QGDKANCLPHKGHEFIPTLYHFPTNCEACSKPLWHVFKPPPALECRRCHVKCHKDHLDKKEDMITPCKVNYDVTSARDMLLLALSQDEQKKWIGHLGKKIPKTPPSTFARQSPRSMSVRSGANQSFRKNPKNVPGKPSRAQSILQAADTTSSTC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXE3-1", "uniprot_id": "Q9VXE3_DROME", "id": "Q9VXE3-1", "name": "Rho-associated protein kinase", "aln": "MPAGRETVTKQRSMDVERRRRANTLEREMRDPTSICNVDCLLDTVSALVSDCDHESLRRLKNIEQYAAKYKPLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYDIPEKWAIFYTMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSNAVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWSFDNIRESVPPVVPELSSDDDTRNFEDIERDEKPEEVFPVPKGFDGNHLPFIGFTYTGDYQLLSSDTVDAESKEANVANSGAASNNHGHGHNHRHRPSNSNELKRLEALLERERGRSEALEQQDAGLRQQIELITKREAELQRIASEYEKDLALRQHNYKVAMQKVEQEIELRKKTEALLVETQRNLENEQKTRARDLNINDKVVSLEKQLLEMEQSYKTETENTQKLKKHNAELDFTVKSQEEKVRDMVDMIDTLQKHKEELGQENAELQALVVQEKNLRSQLKEMHKEAENKMQTLINDIERTMCREQKAQEDNRALLEKISDLEKAH----AGLDFELKAAQGRYQQEVKAHQETEK---SRLVSREEANLQEVKALQSKLNEEKSARIKADQHSQEKERQLSMLSVDYRQIQLRLQKLEGECRQESEKVAALQSQLDQEHSKRNALLSELSLHSSEVAHLRSRENQLQKELSTQREAKRRFEEDLTQLKSTHHEALANNRELQAQLEAEQCFSRLYKTQANENREESAERLS-------KIEDLEEERVSLKHQVQVAVARADSEALARSIAEETVADLEKEKTIKELELKDFVMKHRNEINAKEAALATLKEAENELHKKLGQKAAEYEDLVQQHKKQQEELALMRSSKDEEITKLLDKCKN-EVLLKQVAVNKLAEVMNRRDSDLPKQKNKARSTAELRKKEKEMRRLQQELSQERDKFNQLLLKHQ----DLQQLCAEEQQLKQKMVMEIDCKATEIENLQSKLNETA----SLSSADNDPEDSQHSSLLS-----------LTQDSVFEGWLSVPNKQNRRRGHGWKRQYVIVSSRKIIFYNSDIDKHNTTDAVLILDLSKVYHVRSVTQGDVIRADAKEIPRIFQLLYAGEGASHRPDEQSQLDVSVLHGNCNEERPGTIVHKGHEFVHITYHMPTACEVCPKPLWHMFKPPAAYECKRCRNKIHKEHVDK-HDPLAPCKLNHDPRSARDMLLLAATPEDQSLWVARLLKRIQKSGYKAASYNNNSTDGSKISPSQSTRSSYKPYAVNVQRSATLPANSSLK----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . * :.:: ::**.* * ***** :.*** * *. :**: *.*::: :** :*.:***:.**:..:*:** ************:: :***** ******:**.*********.***.*** *:***.:**** :******::*****:*.**.:**:***** *** ******* **.***:************. ************:*. :* * ...*************:*** *. ***********:******.*:************.***:***:*:** : :**::** ** ****** **** *:::** * **:** *:::.:*::..****:**.* ** **:*:*.*. **.**:**.* **:***:**** .: : ....:.: :: . : : :: . . .*:: : : :: * . *:: : :::: : . .:: * **: : **. . :*.:** * *:: * : : :**: :* *:*: .*::** * :: ::*::.. :*:* ::*:. ::.. *. *:: : :. *.: :: :**: : *:. .: .* : : :: * :: :. :.: :.: : . ** : .*:::**: * * :**:. *: *: .: * **:: : ::.*:.** * :*:.: : *:* ***..* :* ::::* : .: .: * * **:** .** .**. : .*:. *:*:::*:.: * ** .* :*:**.. :: .: **** ****** ** *****.:* ::* *: ::::*:.*: :* *:::: ::*:** ***.: ** :* :* *. . : ::**. *: ::: *::::. * *.: * :: :: : ::* :.. ..:. :* . * ** *******:***:* . ::: .* :******* *:** **.**::***:: .*:* ::* .** :::: *:: .* ::**:*: ** : . * :. *. ...: * :****::**: * :* :***:***:***:*::***.: **. :.. ::**:.*::***.****** **::.***:***:***.** .:: : ::. : : ::.. ******: **:*: *:.*.*****:****.* **:**: * *::*:** .* : ***:.:* ********* . ::*. *: :* *:* *. . . : . : ..** *. * . : . ", "identical_positions": 530, "similar_positions": 442, "identity": "37.09%" }, { "cls_id": "homologset.agr.RGD:620426", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M8G0-1", "uniprot_id": "PHTF1_RAT", "id": "F1M8G0-1", "name": "Protein PHTF1", "aln": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKPDLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVTAIVLYLMMP-------------------------------------IVSVSEVLGPLCLMLLMGTVHCQIVSTQITR-PSGNNGNRRRRKLRKTVNGD--GTRDNGNNSPDKIRAVETLDSAPSVGGFWGTLFGNRIKR----------------------------------VKLVSNKGTETDNDSGCFHPIIKKRQGRPEIRMWQAREKAKVSDGEKCRREAYRR---------LGNGVSDDLSSEEDGEARTQMILLRRSVEGASSDNGCEVKNRKSILSRHLNSQVKKTATRWCHIVRDSDSLAESEFESAAFSQGSRSGMSGGSRSLN--LSRRDSESTRHDSETEDMLWDDLLHGPECRS------------SVTSDSEGAHVNTLHSGTKRDPKEDVFQQN-------HLFWLQNSSPASERVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYEQGVGYQMLGNAVTIGLALFPFLYRLFREKS---FDQLKSISAEEVLTLFCGAPPVTPVVILSIIN-------------FFERLCLTWIFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSYLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLQGHKTFLNDAYNWEFLIWETALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ09-1", "uniprot_id": "PHTF1_MOUSE", "id": "Q9QZ09-1", "name": "Protein PHTF1", "aln": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKPDLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVTAVVLYLLMP-------------------------------------IVSASEVLGPLCLMLLMGTVHCQIVSTQITR-PSGNNGNRRRRKLRKTVNGD--GSRDNGNNSPDKVRAVETLESASSVGGFWGTLFGNRIKR----------------------------------VKLVSNKGTETDNDSGCFHPILKKRQGRPEIRMWQAREKAKVSDGEKCRREAYRR---------LGNGISDDLSSEEDGEARTQMILLRRSVEGASSDNGYEVKNRRSILSRHLNSQVKKT-TRWCHIVRDSDSLAESEFESAVFSQGSRSGMSGGSRSLN--LSRRDSESTRHDSETEDMLWDDLLHGPECRS------------SVTSDSEGAHVNTIHSGTKRDPKEDVFQQN-------HLFWLQNSSPASERVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYEQGVGYQMLGNAVTVGLALFPFLYRLFREKS---FDQLKSISAEEVLTLFCGAPPVTPVVILSIIN-------------FIERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSYLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLQGHKTFLNDAYNWEFLIWETALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMS5-1", "uniprot_id": "PHTF1_HUMAN", "id": "Q9UMS5-1", "name": "Protein PHTF1", "aln": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGLKNKPKKMGHIKPDLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSNWWIQVTSLRIFVWLLLLYFMQVIAIVLYLMMP-------------------------------------IVNISEVLGPLCLMLLMGTVHCQIVSTQITR-PSGNNGNRRRRKLRKTVNGD--GSRENGNNSSDKVRGIETLESVPIIGGFWETIFGNRIKR----------------------------------VKLISNKGTETDNDPSCVHPIIKRRQCRPEIRMWQTREKAKFSDGEKCRREAFRR---------LGNGVSDDLSSEEDGEARTQMILLRRSVEGASSDNGCEVKNRKSILSRHLNSQVKKTTTRWCHIVRDSDSLAESEFESAAFSQGSRSGVSGGSRSLN--MSRRDSESTRHDSETEDMLWDDLLHGPECRS------------SVTSDSEGAHVNTLHSGTKRDPKEDVFQQN-------HLFWLQNSSPSSDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNVVTIGLAFFPFLHRLFREKS---LDQLKSISAEEILTLFCGAPPVTPIIVLSIIN-------------FFERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSYLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLQGHKTFLNDAYNWEFLIWETALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V9A8-1", "uniprot_id": "PHTF_DROME", "id": "Q9V9A8-1", "name": "Protein phtf", "aln": "--MKLDEIVAWYQKRIGTYDKQEWEKTVEQRILDGFNSVNLKNTKLKTELIDVDLVRGSTFPKAKPKQSLLTVIRLAILRYVLLPLYAQWWVKQTTPNAFGFILVLYLTQLTNWAIYVLHSSRIVPLDYEKPPNGTLLQAEADGDASDKDADKESEEHAALLSALLIPCALSLLISLIHSQIVATNTASGVSGGSSKNKLRRISASYLSDKAATRENRVRRRKKIVRVRQVEADLSQASSNISLPNRRTATSTIEVLPRPVTPLPSPTVTCATVPDPTTPTTPSPSVIRRSTNEETYLTTTAISPLTQPLAAIDACYDLSRKAGGAAPESPKKRNVNWHTPIQIYATYELGEEPCSSRKVAEESAPESVGERLCSVKPDYQTRRNIGEDDGFESLNGKSSSGEDNNHSPLPNAVAVAAPPAPVQTNQLRLRLNTTNGVTASASPTEKKPQSRGNESSTSCAESDECDDADIMSSPASGCNQECTTSATDWLGVTTNSEDCSYTSDLDHSDGGLKHTAFSDEDPGELDITPTTILNPHSSLDRISCTIWDQRDAKKAQLSVLEIASCIIERVDSMGEANDYIYIGVVFSFLLTLIPIFCRLCEVTLGSDAEKASEISYFNMPQLLWEKSSASLFTLLGLAFGDSQWERMVLALGFVQRLCLTLILFIIFAVAERTFKQRFLYAKLFSHLTSSRRARKSNLPHFRLNKVRNIKTWLSVRSYLKKRGPQRSVDIIVSAAFIVTLLLLAFLSVEWLK-DSAHLHTHLTLEALIWSITIGIFLLRFMTLGQKIQHKYRSVSVLITEQINLYLQIEQKPKKKDELMVSNSVLKLAADLLKELETPFKLSGLSANPYLFTTIKVVILSALSGVLSEVLGFKLKLHKIKIK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::****:**:**:* ***::** :.*::. * ::*.:******:*****.****: . :: * .::* *::**::.**:: *: . * ::*:**: *: .:*:: . . * :* * .* **:. :*.***:*: : **...:.: *:: : .* .:*:* . .*: :. ::: .. :: ..* : ... ** . .. *: : . : . .:. * *. :: **: ... . *:. ..: * . .: .. .: . *. : .* .:. : : * : . * : :. : .: .*::..: . : . *..**: :*::: *:: .* . . .**::**.. .: . :. . *. .*.:: : *. .: :*:*. **: .:.** ::*****:. *:.**:: :. .* :* ..:. *:::*:: ** . . :: ..** :: *: ...: . :*.: *.:***** ::*:::.*****:*****:******:**:*:*** ::*****:**.*** ***:*****:********::**:.*::** : : ..: *: ..:.*: . * ***. :: :****: :**.: ::** .**:*:********::*:**:**::* : *.****::.*****:***:* **: ** ::. :******:***:*::***:::* *** ", "identical_positions": 242, "similar_positions": 296, "identity": "27.41%" }, { "cls_id": "homologset.agr.RGD:620427", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q53GG5-1", "uniprot_id": "PDLI3_HUMAN", "id": "Q53GG5-1", "name": "PDZ and LIM domain protein 3", "aln": "MPQTVILPGPAP--------------------------------------WGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGE-----------------THLWSPQVSEDG--KAHPFKINLESEPQDGNYFEHKHNIRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMELPGVKIVHAQFNTPMQLYSDDNIMETLQG-QVSTALGETPLMSEPTASVPPESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCN--------------------------------LNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTLYPKA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66HS7-1", "uniprot_id": "PDLI3_RAT", "id": "Q66HS7-1", "name": "PDZ and LIM domain protein 3", "aln": "MPQNVVLPGPAP--------------------------------------WGFRLSGGIDFNQPLVITRITPGSKAEAANLCPGDVILAIDGFGTESMTHADAQDRIKAASYQLCLKIDRAE-----------------TRLC-PAVSEDG--KAHPFKINLEAEPQDVNYFEHKHNIRPKPFIIPGRTSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKMAPNIPLEMELPGVKIVHAQFNTPMQLYSDDNIMETLQG-QVSTALGETPSMSEPTASVPPQSDVYRMLHDNRDEPAAPRQSGSFRVLQELVNDGSDDRPAGTRSVR-PVTKVHGGAGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCN--------------------------------LNLKQKGYFFVEGELYCEMHARARTRPPEGYDTVTLYPKA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70209-1", "uniprot_id": "PDLI3_MOUSE", "id": "O70209-1", "name": "PDZ and LIM domain protein 3", "aln": "MPQNVVLPGPAP--------------------------------------WGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAASYQLCLKIDRAE-----------------TRLWSPQVSEDG--KAHPFKINLEAEPQEFKPIGTAHNRRAQPFVAAAN---------IDDKR--------------------------------------QVVSASYNSPIGLYSTSNIQDALHG-QLRGLIPGS-LQNEPTASVPPQSDVYRMLHDNRDDPAAPRQSGSFRVLQDLVNDGPDDRPAGTRSVRAPVTKVHGGAGSAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCN--------------------------------LNLKQKGYFFVEGELYCETHARARTRPPEGYDTVTLYPKA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B416-1", "uniprot_id": "A0A8M2B416_DANRE", "id": "A0A8M2B416-1", "name": "PDZ and LIM domain protein 3", "aln": "MPQNVVLDGPAP--------------------------------------WGFRLSGGKDFNQPLTITRVTPGSKASRVNLCPGDIILSIQGVSTDGMTHAEAQNNIKDSTNQLFLKIERPE-----------------TKIWSPQVIEEG--KVNPFKINLEAEKQDIDYFEHKFNVRPKPFTSASQRSDSTSQTLMGNVAQMAGTPS-------------------------------TAHSVQYNSPIALYSADNVSNTLQQAQMSTVVRQASPSSKPLTSIED-SHVYRMLQDANEQPHEPRQSGSFKALQDYVES-DGTRPMVTRSVKAPVTKPQAATSSLQKLPLCDKCGTGIVGTVVKARDKYRHPACFVCSDCG--------------------------------MNLKQKGYFFVDGQMYCEAHARMRMTPPEGHDLVTVYPTA-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZE5-1", "uniprot_id": "B7YZE5_DROME", "id": "B7YZE5-1", "name": "PDZ domain-containing protein", "aln": "MPEQLGLLWSVPESKSKAPIIKVSCGIGDTDGYPAFDVDSDAYATKDDSRWGFLITGGAEFHMPLTVFQVTPNGLADKAGIRLGDIILEINEEDASQLTLSQAHEKINSTPKKIHFLLRNMEEDDPMGQFEAGEEKSIVMRVPKPLPPPSGRIRASSIEMRLLEMQRKLSAIAEIPKILCSTLATVSQNFGRMSESEVDEDDVGEEEAYVQRKFSYDEDALDFELRNGEQAG--------DTDSDEEDLVLVREEDAEDVDVPKGAKQSKLLKDVTPESDYASEANYPANEASDDTESDDE-DEPGSTVYFMKLPAAAAEDTYSSTEDEDDSDFLNTTYTWNLRNVPKLRINDAEAEGELTLGHQAREVPQQEQPQEKQPCLEPEPPKVRPATPTPKAPPQESAEGQTQKLLFRLDKLERSWPWADREKIIYKQSTCHLVPRKPLGLVGQRMQLLLKDKKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: : * ..* *** ::** :*: **.: ::**.. * ..: **:** *: .:. :* ::*::.*: :. :: : : . * :: * .* :. .:::.* :. . : : ..: .. :. . : : . : :. : : : .. :. :. : :: * .: * * . . . . *. . :: : * . * : :**: :: * :: ::.: : : : :: : * : . * ", "identical_positions": 38, "similar_positions": 108, "identity": "8.24%" }, { "cls_id": "homologset.agr.RGD:620428", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06909-1", "uniprot_id": "CFAH_MOUSE", "id": "P06909-1", "name": "Complement factor H", "aln": "MRLSARIIWLILWTVCA-AEDCKGPPPRENSEILSGSWSEQLYPEGTQATYKCRPGYRTLGTIVKVCKNGKWVASNPSRICRKKPCGHPGDTPFGSFRLAVGSQFEFGAKVVYTCDDGYQLLGEIDYRECGADGWINDIPLCEVVKCLPVTELENGRIVSGAAETDQEYYFGQVVRFECNSGFKIEGHKEIHCSENGLWSNEKPRCVEILCTPPRVENGDGINVKPVYKENERYHYKCKHGYVPKERGDAVCTGSGWSSQPFCEEKRCSPPYILNGIYTPHRIIHRSDDEIRYECNYGFYPVTGSTVSKCTPTGWIPVPRCTLKPCEFPQFKYGRLYYEESLRPNFPVSIGNKYSYKCDNGFSPPSGYSWDYLRCTAQGWEPEVPCVRKCVFHYVENGDSAYWEKVYVQGQSLKVQCYNGYSLQNGQDTMTCTENG--WSPPPKCIRIKTCSASDIHIDNGFLSESSSIYALNRETSYRCKQGYVTNTGEISGSITCLQNGWSPQPSCIKSCDMPVFENSITKNTRTWFKLNDKLDYECLVGFENEYKHTKGSITCTYYGWSDTPSCYERECSVPTLDRKLVVSPRKEKYRVGDLLEFSCHSG-HRVGPDSVQCYHFGWSPGFPTCKG-QVASCAPPLEILNGEINGAKKVEYSHGEVVKYDCKPRFLLKGPNKIQCVDGNWTTLPVCIEEERTCGDIPELEHGSAKCSVPPYHHGDSVEFICEENFTMIGHGSVSCISGKWTQLPKCVATDQLEKCRVLKSTGIEAIKPKLTEFTHNSTMDYKCRDKQEYERSICINGKWDPEPNCTS--KTSCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDSEEMVCKDGRWQSLPRCIEKIPCSQPPTIEHGSINLPRSSEERRDSIESSSHEHGTTFSYVCDDGFRIPEENRITCYMGKWSTPPRCVGLPCGPPPSIP-LGTVSLELESYQHGEEVTYHCSTGFGIDGPAFIICEGGKWSDPPKCIKTDCDVLPTVKNAIIRGKSKKSYRTGEQVTFRCQSPYQMNGSDTVTCVNSRWIGQPVCKDNSCVDPPHVPNATIVTRTKNKYLHGDRVRYECNKPLELFGQVEVMCENGIWTEKPKCRDSTGKCGPPPPIDNGDITSLSLPVYEPLSSVEYQCQKYYLLKGKK-TITCRNGKWSEPPTCLHACVIPENIMESHNIILKWRHTEKIYSHSGEDIEFGCKYGYYKARDSPPFRTKCINGTINYPTCV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q8B5-1", "uniprot_id": "E9Q8B5_MOUSE", "id": "E9Q8B5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGFCSML--LLSNILLTAWLSTAKGEVKSCEFPQFKYGRLYYEEILRPNFPVSIGNKYSYKCDNGFSPPSGIFWDYLRCTVQGWEPEVPCVRKCVFHYVENGQSAYWEKIYVQGQSLKVQCYNGYSLQNGQDTMTCTENG--WSPPPKCIRIKTCSVSDIEIENGFFSESFRTYALNRETSYRCKQGYVTNTGETSGSITCLQNGWSPQPSCIKSCERPVFENSVTKNNSTWFKLNDKLDYECLIGYENEYKHTKGSITCTYYGWSDTPSCYEIECSVPILDRKLVVSPRKEKYRVGDLLEFSCRSG-HRVGPDSVQCYHFGWSPSFPTCKAGQVASCAQPPEIPNGEINGAKRVEYSHGEVVGYDCKPRFLLKGPNKIQCVDGMWTTLPVCVEEERTCGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCLSGKWTQLPKCVATDQLEKCRVLKSTDIEAIKPKRKEFQHNSTMYYKCRDKQEYEHSICINGKWNPEPNCIR--KISCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDPEEMMCKDGRWQSLPHCIEKIPCSQPPTIEHGSIKLPRTSEKRRKSIEFSSHEHGTTFSYVCDDGFRIPEENGVACYMGKWSTPPRCVGLPCGPPPSIP-LGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKCEGGKWSDPPKCIKTDCDILPTIENAIIRGKNKKSYRTGEQVTVRCQSPYQMNGSDTVTCINGRWIGKPVCKD-----------------------------------------------------------SRGKCGPPPPIDNGDITSLSLPEYEPFSSVDYQCQKYYLLKGKK-TITCRNGKWSEPPTCLHACIIPENIMEARKIILKWRHTKNIYSHSGEDIEFECKYGYHKARGSPPFRTKCISGTINYPICE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V9R2-1", "uniprot_id": "G3V9R2_RAT", "id": "G3V9R2-1", "name": "Complement factor H", "aln": "MRLSARIIWLILWTVCV-AEDCKGPPPRENSEILSGSWSEQLYSEGTQATYKCRPGYRTLGTIVKVCKNGEWVPSNPSRICRKRPCGHPGDTPFGSFRLAVGSEFEFGAKVVYTCDEGYQLLGEIDYRECDADGWTNDIPICEVVKCLPVTELENGRIVSGAAEPDQEYYFGQVVRFECNSGFKIEGQKEMHCSENGLWSNEKPQCVEISCLPPRVENGDGIYLKPVYKENERFQYKCKQGFVYKERGDAVCTGSGWNPQPSCEEMTCLTPYIPNGIYTPHRIKHRIDDEIRYECKNGFYPATRSPVSKCTITGWIPAPRCSLKPCDFPQFKHGRLYYEESRRPYFPVPIGKEYSYYCDNGFTTPSQSYWDYLRCTVNGWEPEVPCLRQCIFHYVEYGESLYWQRRYIEGQSAKVQCHSGYSLPNGQDTILCTENG--WSPPPKCVRIKTCSVSDIEIENGFFSESDYTYALNRKTRYRCKQGYVTNTGEISGIITCLQDGWSPRPSCIKSCDMPVFENAMTKNNNTWFKLNDKLDYECHIGYENEYKHTKGSITCTYDGWSSTPSCYERECSIPLLHQDLVVFPREVKYKVGDSLSFSCRSG-HRVGADLVQCYHFGWSPNFPTCEG-QVKSCDQPLEIPNGEIKGTKKVEYSHGDVVEYDCKPRFLLKGPNKIQCVDGKWTTLPICVEYERTCGDLPALEHGSVQLSVPPYHHGDSVEFTCAETFTMIGHAVVFCISGRWTELPQCVATDQLEKCKAPKSTGIDAIHPNKNEFNHNFSVSYRCRQKQEYEHSICINGRWDPEPNCTRNEKRFCPPPPQIPNAQVIETTVKYLDGEKVSVLCQDGYLTQGPEEMVCKHGRWQSLPRCTEKIPCSQPPKIEHGSIKSPRSSEER-DLIESSSYEHGTTFSYVCDDGFRISEENRVTCNMGKWSSLPRCVGIPCGPPPSIP-LGIVSHELESYQYGEEVTYNCSEGFGIDGPAFIKCVGGQWSEPPKCIKTDCDNLPTFEIAKPTEKKKKSYRSGEQVTFRCPPPYRMDGSDIVTCVNTKWIGQPVCKDNSCVNPPHVPNATILTRHKTKYPSGDKVRYDCNKPFELFGEVEVMCQNGIWTEPPKCKDSTGKCGPPPPIDNGDITSLSLPVYAPLSSVEYQCQNYYLLKGNK-IVTCRNGKWSQPPTCLHACVIPEDIMEKHNIVLRWRENAKIYSQSGENIEFMCKPGYRKFRGSPPFRTKCIEGHINYPTCV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08603-1", "uniprot_id": "CFAH_HUMAN", "id": "P08603-1", "name": "Complement factor H", "aln": "MRLLAKIICLMLWAICV-AEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTTVTCMENG--WSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAQPTCIKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSPDLPICKE-QVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQES--------YAHGTKLSYTCEGGFRISEENETTCYMGKWSSPPQCEGLPCKSPPEIS-HGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCINSRWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNK-RITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N898-1", "uniprot_id": "A0A8M1N898_DANRE", "id": "A0A8M1N898-1", "name": "", "aln": "MRVPVKLLGFVVWLLCLNFGQCRDCLRSDIIYENIVPVSDASYADGKTAKVFCQIGFT--GIYILKCENGKWSERVG-RTCKKKKCSHPGDAANADFKLLDGTEFVFGTTVVYTCKKGYEMTSRSNKRTCTSKGWDNSVPECEAVKCP----------------------------------------------------------------------------------------------------------------------------------------------------------------------AILTNRDVIASGNTKEGNYG----------------------------------------------------------------------------EVIHFECASSEKKIDGSRDIRCTETGDWSAPVPNCIAVTCELTSNVDVKR-VVPEGKTIFRAGERVTITCTEKTWLKSKETSRRFTCQDDGQ----------------------------------------------------------WDYNPVCEVITCEPPSRDQHVSTYFWR-TWKLDESKNYECDSG-YYKKAEVATCTRDGLTP-KPLCAG----MCARP-DIPNAKIEGVPRQNYSTASTLRYKCNPGFEPEETVEITCNP-----------------------------------------------------------QAQWTGLQQCTAKREDCHDLSVKNGFIYSQSLNKKEILYSCNKGYKPFTGEWWSSVTCVKGSWS-------------------------------------------------------------DVPLCIPEEECGALPSVQNGKLKLKDQ----------------ETAEVDCDPGF-ISSTPSIKCISGTWETPTCNEGVKCGIPPYVGNSGITSKPKAFYIHGSSVTYTCRNPFVMIGKSTVFCSNGKWEETPTCEAR---CLRPHENYMVLATDKDTYQDKEILNYQCMKPYDKIPEGEWICENGKWTGDFVCTS-------------------------------------------------------------DICPPPPYIENGSHFSRNPDDKMPT-EVYYECQAYYVLSERKQYYRCENGRWETPPKCLKPCQVTQDILEAHNMRP---DQQTGYIKHGDYVDYYCQHRLIVRTG-HYKKATCSDGKLEIESCE--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . : : ::* : .. * . ... : * *.* :* *.*: :. *.:.:.. ...*. : ... *. * * :** .:* *. * * *. * . .: . :::.: .:.* .* .: . * : * :* * * * * :: *.::: : :*. ...: * *:* * : . :* * . ** * :*.* : : : : : .*: :. . *: : : *::* *. .:* * : *. * :::*.:: . . *: ** *.. * *.*.: . *: * ** : * .: * :*..*** * * : * : * . :*...*.* * . : .*. *: * :. * * . * * :* * .* . . * *** *:**. * * .* *:** * *. .* *.**:*. **.**:.* :..:*:* :: . * : *: ::: *: ::.* .* :: * ", "identical_positions": 121, "similar_positions": 175, "identity": "9.72%" }, { "cls_id": "homologset.agr.RGD:620429", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61129-1", "uniprot_id": "CFAI_MOUSE", "id": "Q61129-1", "name": "Complement factor I", "aln": "MKLAHLSLFLLALHLSSSRSPSASDLPQEELVDQKCLLQKYTHRSCNKVFCQPWQRCIEGTCICKLPYQCPRAGTPVCAMNGRSYPTYCHQKSFECLHPEIKFSHNGTCAAEGKFNVSLIYGRTKTEGLVQVKLVDQDERMFICKNSWSMAEANVACVDLGFPLGVRDIQGSFNISGNLHINDTECLHVHCRGVETSLAECAFTKRRTELSNGLAGVVCYKQDADFPTSLSFQCVNGKHIPQEKACNGVNDCGDQSDELCCKGCRGNASLCKSGVCIPDQYKCNGEVDCITGEDESRCEEDRQQNIPKGLARSAQG-EAEIETEETEMLTPGMDNERKRIKSLLPKLSCGVKRNTHTRRKRVIGGKPANVGDYPWQVAIKDGQRITCGGIYIGGCWILTAAHCVRPSRAHSYQVWTALLDWLKPNSQ-LGIQTVKRVIVHEKYNGATFQNDIALIEMKMHTGKKECELPNSVPACVPWSPYLFQPNDRCIISGWGRGKDNQKVYSLRWGEVDLIGNCSQFYPDRYYEKEMQCAGTRDGSIDACKGDSGGPLVCEDINNVTYVWGIVSWGENCGKPEFPGVYTRVANYFDWISYHVGRSLVSQHNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WUW3-1", "uniprot_id": "CFAI_RAT", "id": "Q9WUW3-1", "name": "Complement factor I", "aln": "MKLALLILLLLNPHLSSSKNTPASGQPQEDLVEQKCLLKNYTHHSCDKVFCQPWQKCIEGTCACKLPYQCPKAGTPVCATNGRGYPTYCHLKSFECLHPEIKFSNNGTCTAEEKFNVSLIYGSTDTEGIVQVKLVDQDEKMFICKNSWSTVEANVACFDLGFPLGVRDIQGRFNIPVNHKINSTECLHVRCQGVETSLAECTFTKKSSKAPHGLAGVVCYTQDADFPTSQSFQCVNGKRIPQEKACDGVNDCGDQSDELCCKGCRGQAFLCKSGVCIPNQRKCNGEVDCITGEDESGCEEDKKNKIHKGLARSDQGGETEIETEETEMLTPDMDTERKRIKSLLPKLSCGVKRNTHIRRKRVVGGKPAEMGDYPWQVAIKDGDRITCGGIYIGGCWILTAAHCVRPSRYRNYQVWTSLLDWLKPNSQ-LAVQGVSRVVVHEKYNGATYQNDIALVEMKKHPGKKECELINSVPACVPWSPYLFQPNDRCIISGWGREKDNQKVYSLRWGEVDLIGNCSRFYPGRYYEKEMQCAGTSDGSIDACKGDSGGPLVCKDVNNVTYVWGIVSWGENCGKPEFPGVYTRVASYFDWISYYVGRPLVSQYNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05156-1", "uniprot_id": "CFAI_HUMAN", "id": "P05156-1", "name": "Complement factor I", "aln": "MKLLHVFLLFLCFHLRFCKVTYTS---QEDLVEKKCLAKKYTHLSCDKVFCQPWQRCIEGTCVCKLPYQCPKNGTAVCATNRRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGA-DTQRRFKLS-DLSINSTECLHVHCRGLETSLAECTFTKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAG-----------------FASVTQEETEILTADMDAERRRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGRPFISQYNV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** : *::* ** .: . :* **:**::*** ::*** **:********:****** ********: **.*** * *.:****: **:***** ** :****:** **.*** :* *.:**:*:*******: *****.*** ******.**** *. * * *::. : **.******:*:*:*******:***: : :.:*.****.*.** * . ******* *.* ***:*:*************.*:*:. ********.* :************* * :.: ****:**..** **:**************.. * ****::*** *::** ********.. *******************:*.*: : **:**:::**::*: : : :: *.*::.**:**..*:******:*** . .**:*** .*:*************** **:***** ***::*:**:****.**.***:** .*:*****:**** ***************** * ********:*****************:**.*******:***.::**:**", "identical_positions": 388, "similar_positions": 122, "identity": "64.13%" }, { "cls_id": "homologset.agr.RGD:62043", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P22985-1", "uniprot_id": "XDH_RAT", "id": "P22985-1", "name": "Xanthine dehydrogenase/oxidase", "aln": "---MTADELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLQNKIVHFSVNACLAPICSLHHVAVTTVEGIGNTQ-KLHPVQERIARSHGSQCGFCTPGIVMSMYTLLRNQPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCMNQTK--DQTVSLSPSLFNPEDFKPLDPTQEPIFPPELLRLKDTPQKKLRFEGERVTWIQASTMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIVCPAWIPELNSVVHGPEGISFGASCPLSLVESVLAEEIAKLPEQKTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDLNPVFMASGAKLTLVS----RGTRRTVRMDHTFFPGYRKTLLRPEEILLSIEIPYSKEGEFFSAFKQASRREDDIAKVTSGMRVLFKPGTIEVQELSLCFGGMADRTISALKTTPKQLSKSWNEELLQSVCAGLAEELQLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEDMCGKLDPTFASATLLFQKDPPANVQLFQEVPKDQSEEDMVGRPLPHLAANMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTAEDVPNSN--ATGLFNDETVFAKDEVTCVGHIIGAVVADTPEHAQRAARGVKITYEDL-PAIITIQDAINNNSFYGSEIKIE-KGDLKKGFSEADNVVSGELYIGGQEHFYLETNCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPDNRIVVRVKRMGGGFGGKETRSTVVSTALALAAHKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTVVALEVAHFSNGGNTEDLSRSIMERALFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAITCGLPAEEVRRKNMYKEGDLTHFNQKLEGFTLPRCWDECIASSQYLARKREVEKFNRENCWKKRGLCIIPTKFGISFTLPFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHISETSTNTVPNTSPTAASASADLNGQGVYEACQTILKRLEPFKKKKPTGPWEAWVMDAYTSAVSLSATGFYKTPNLGYSFETNS-GNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFLASSIFFAIKDAIRAARAQHGD-NAKQLFQLDSPATPEKIRNACVDQFTTLCVTGVPENCKSWSVRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00519-1", "uniprot_id": "XDH_MOUSE", "id": "Q00519-1", "name": "Xanthine dehydrogenase/oxidase", "aln": "MTRTTVDELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLQNKIVHFSVNACLTPICSLHHVAVTTVEGIGNTK-KLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCMSQTK--DQTIAPSSSLFNPEDFKPLDPTQEPIFPPELLRLKDTPRKTLRFEGERVTWIQVSTMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGAACPLSLVESVLADAIATLPEQRTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDLNPVLMASRAKLTLAS----RGTKRTVWMDHTFFPGYRRTLLSPEEILVSIVIPYSRKGEFFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELSLCFGGMADRTVSALKTTPKQLSKSWNEELLQDVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEGMCGKLDPTFASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPMPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSN--ITGIFNDETVFAKDEVTCVGHIIGAVVADTPEHAHRAARGVKITYEDL-PAIITIQDAIKNNSFYGPEVKIE-KGDLKKGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIAKMLGVPDNRIVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYKIPNIRGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKLEGFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPTAASASADLNGQAIYEACQTILKRLEPFKKKNPSGSWESWVMDAYTSAVSLSATGFYKTPNLGYSFETNS-GNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFLASSIFFAIKDAIRAARAQHGDSNAKQLFQLDSPATPEKIRNACVDQFTTLCATGTPENCKSWSVRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47989-1", "uniprot_id": "XDH_HUMAN", "id": "P47989-1", "name": "Xanthine dehydrogenase/oxidase", "aln": "---MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCMNQKK--DHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVS----RGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSN--ITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL-PAIITIEDAIKNNSFYGPELKIE-KGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGYSFETNS-GNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTGVPENCKPWSVRV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10351-1", "uniprot_id": "XDH_DROME", "id": "P10351-1", "name": "Xanthine dehydrogenase", "aln": "---MSNSVLVFFVNGKKVTEVSPDPECTLLTFLREKLRLCGTKLGCAEGGCGACTVMVSRLDRRANKIRHLAVNACLTPVCSMHGCAVTTVEGIGSTKTRLHPVQERLAKAHGSQCGFCTPGIVMSMYALLRNAEQPSMRDLEVAFQGNLCRCTGYRPILEGYKTFTKEFACGMG----EKCCKVSGKGCGTDAETDDKLFERSEFQPLDPSQEPIFPPELQLSDAFDSQSLIFSSDRVTWYRPTNLEELLQLKAKHPAAKLVVGNTEVGVEVKFKHFLYPHLINPTQVKELLEIKENQDGIYFGAAVSLMEIDALLRQRIEQLPESETRLFQCTVDMLHYFAGKQIRNVACLGGNIMTGSPISDMNPVLSAAGAQLEVASFVDGKLQKRSVHMGTGFFTGYRRNVIEAHEVLLGIHFRKTTPDQYIVAFKQARRRDDDIAIVNAAINVRFEEKSNIVAEISMAFGGMAPTTVLAPRTSQLMVGQEWSHQLVERVAESLCTELPLAASAPGGMIAYRRALVVSLFFKAYLAISLKLSKSGIT-SSDALPSEERSGAETFHTPVLKSAQLFERVCSDQPICDPIGRPKVHAAALKQATGEAIYTDDIPRMDGEVYLAFVLSTKPRAKITKLDASEALALDGVHQFFCYKDLTEHENEVGPVFHDEHVFAAGEVHCYGQIVGAIAADNKALAQRAARLVKVEYEELSPVIVTIEQAIEHKSYFPDYPRFVTKGNVEEALAQADHTFEGTCRMGGQEHFYLETHAALAVPR-DSDELELFCSTQHPSEVQKLVAHVTALPAHRVVCRAKRLGGGFGGKESRGISVALPVALAAYRMGRPVRCMLDRDEDMLITGTRHPFLFKYKVGFTKEGLITACDIECYNNAGWSMDLSFSVLERAMFHFENCYRIPNVRVGGWVCKTNLPSNTAFRGFGGPQGMYAGEHIIRDVARIVGRDVVDVMRLNFYKTGDYTHYHQQLEHFPIERCLEDCLKQSRYDEKRQEIARFNRENRWRKRGMAVVPTKYGIAFGVMHLNQAGSLINIYGDGSVLLSHGGVEIGQGLNTKMIQCAARALGIPSELIHISETATDKVPNTSPTAASVGSDLNGMAVLDACEKLNKRLAPIKEALPGGTWKEWINKAYFDRVSLSATGFYAMPGIGYHPETNPNARTYSYYTNGVGVTVVEIDCLTGDHQVLSTDIVMDIGSSLNPAIDIGQIEGAFMQGYGLFTLEELMYSPQGMLYSRGPGMYKLPGFADIPGEFNVSLLTGAPNPRAVYSSKAVGEPPLFIGSSAFFAIKEAIAAARE---DQGLSGDFPLEAPSTSARIRIACQDKFTELLEIPEPGSFTPWNIVP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *******:**.* ..*** ***.:**.** *.******.**********:*: ** *** *::.****:*:**:* *********.*: :*******:*::*****************:**** :*::.::* ****************:*::**::: .* * :** . * . . .**: .:* ****:********* . : * *..:**** : :.::***:***:** *********:*:*:***::*:* :: *: : ** .: .. :** ***: .* :: * : : ** ..*.:*: .:: *::*****::.**.:****:*.*****:***: *: *:* :.* : :*:* *. **.***:.:: ..*:*:.* : : .::: ***** **:**** *.:.:.* *: : * *:::.:**** *: * :*: :.: *..:*:: *. .*. ** *...*****: :* :*.:*:*** **:: **.: .: .. * . *.: *:. ..***:.* ..*. * :*** * ** **:***:* ***** :.*: * :* **:.:*** .:*:*** : *. *: .*:. : : :** *** .:* * *:*:**:.**. ::***: **: **:* *.*:**::**:::*:: :: **::::.:::**:...* :**********:.::***: ::.*:*** ***:. :.*.::*:: .:* :*:* *.**:********:*. :: .:****:: ****************** ***** :***** * * :.* :: :.* * : *** *::***:**::*.*:***:* * :******************** .* : :** * . :* * *:** ** **::*:** *.: ** ::*: .*:* :: *: :**:** *:***:.::***:**:* : .***.*:*:::* ******:***.*:****:***:* *:*** **:. *:*:**:*:.**********..:**** .: **:.: *** * *: * *.*: *: ** . ********* *.:** ***. ...: *:: **. : **********: * ******:************:****:** ****:*** ***:* *::***. **:*.*..** **.**** ..** :*:*:**********:.:* *****:** *** . . . * *::*:*. :** ** *:** * * . ..*.: ", "identical_positions": 660, "similar_positions": 396, "identity": "49.0%" }, { "cls_id": "homologset.agr.RGD:620430", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1J4-1", "uniprot_id": "MYOC_RAT", "id": "Q9R1J4-1", "name": "Myocilin", "aln": "------------------------------------------------------MPSCAYCCSCGPKMPALQLLFLACLVWGMG-----------------------------------------------------------ARTAQFRKANDRSGRCQYTFTVASPSESSCP-----REDQAMSAIQDLQRDSSIQHADLESTKAR-----------------------------VRSLESLLHQMTSGGVTGTQEVQEGLQGQLG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALRRERD------------------QLETQTRDLEVAYNNLLRD-------------------KSALEEEKRQLEQENKDLARRLEGSSQEVARLRRGQ-----CPSTHHPSQDMLPGSREVSQWNLDTLAFQEL-------KSELTEVPASQILK-NQSGHPRSKEGD--------------------------------------KGCGVLMWVGEPVTLRTAETITG-----------KYGVWMRDPKPTHPYTQETTWRIDTVGTGIRQVFEYSQISQFEQG-YPSKVHVLPQALESTGAVVYSGSLYFQGAESRTVLRYELNTETVKAEKEIPGAGYHGQFPYAWGGYTDIDLAVDESGLWVIYSTEETRGAIVLSKLNPENLELESTWETNIRKQSVANAFVICGILYTVSSYSSVHATINFAYDTNTGISKTLTIPFKNRYKYSSMVDYNPLERKLFAWDNFNMVTYDIKLSEM-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70624-1", "uniprot_id": "MYOC_MOUSE", "id": "O70624-1", "name": "Myocilin", "aln": "-------------------------------------------------------------------MPALHLLFLACLVWGMG-----------------------------------------------------------ARTAQFRKANDRSGRCQYTFTVASPNESSCP-----REDQAMSAIQDLQRDSSIQHADLESTKAR-----------------------------VRSLESLLHQMTLGRVTGTQEAQEGLQGQLG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALRRERD------------------QLETQTRDLEAAYNNLLRD-------------------KSALEEEKRQLEQENEDLARRLESSSEEVTRLRRGQ-----CPSTQYPSQDMLPGSREVSQWNLDTLAFQEL-------KSELTEVPASQILKENPSGRPRSKEGD--------------------------------------KGCGALVWVGEPVTLRTAETIAG-----------KYGVWMRDPKPTHPYTQESTWRIDTVGTEIRQVFEYSQISQFEQG-YPSKVHVLPRALESTGAVVYAGSLYFQGAESRTVVRYELDTETVKAEKEIPGAGYHGHFPYAWGGYTDIDLAVDESGLWVIYSTEEAKGAIVLSKLNPANLELERTWETNIRKQSVANAFVICGILYTVSSYSSAHATVNFAYDTKTGTSKTLTIPFTNRYKYSSMIDYNPLERKLFAWDNFNMVTYDIKLLEM-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99972-1", "uniprot_id": "MYOC_HUMAN", "id": "Q99972-1", "name": "Myocilin", "aln": "-----------------------------------------------------MRFFCARCCSFGPEMPAVQLLLLACLVWDVG-----------------------------------------------------------ARTAQLRKANDQSGRCQYTFSVASPNESSCP-----EQSQAMSVIHNLQRDSSTQRLDLEATKAR-----------------------------LSSLESLLHQLTLDQAARPQETQEGLQRELG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLRRERD------------------QLETQTRELETAYSNLLRD-------------------KSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQ-----CPQTRDTARAVPPGSREVSTWNLDTLAFQEL-------KSELTEVPASRILKESPSGYLRSGEGD--------------------------------------TGCGELVWVGEPLTLRTAETITG-----------KYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQG-YPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWZ7-1", "uniprot_id": "Q9VWZ7_DROME", "id": "Q9VWZ7-1", "name": "Colmedin", "aln": "MFLAVNQSLQNTSKKKRKRRTAEDDPQEDSGEGTPPVRPLEPSASSDQLVGVGNGATCRVCKCPGRQSLTLVYIYLGALTLILASLSIVFYTHTQDVESLSQVEDNYSSKSFRVQFQAELMRSEEELRRLVNRIIEEEQELVGSTTASSTTQSRDPLKNERKFTDNLISHTTRPTGKRMRRDIASSAPASMHADPLIEFFNPNHRKVLEEQDTEIRKRTGQKGAAPGGDEWIYLNTYCRVPEKIITGFCKGTQDYCPPAPQGPTGEVGPKGPPGNPGLPGIPGPKGNRGDVGLPGAPGVDGVGHLGPAGPRGPKGDAGATGRAGLDGRDGVPGEPGLDGVPGRAGADGKNGLPGRDGKDGLHGKDGKDGLSITGPKGAQGPPGERGLKGIAGPRGRPGKPGTNGIPGVPGINAWKLQYPNGSSSNDLLIPPSITDIQVPDFQRTVIVEEGRSLNLSCTATGTPTPQVEWRREDGRTINVNGVEMASISGQFLRFTNITRHQMAAYTCFANNGIAPVANATYLVEVQFAPMISVYRQMIYAEYQSSATLECLVEAFPEAIRYWERAYDGKILDPSDKYGIESYPEGFKTTMRLTISNLRKDDFGYYHCVARNELNATMVNFEIAPQDPNSETPYVGNNMKVYGQRPPESECPVCDQCPDPSLYQCKDSILNNFEIQATGNLSYPGLPKRPKTCYLYAVGKPVFHKVVNEKFGSWLRDPSPDS--DREKTFVTNEN--DPYNLFEFTTRIQYRMNSIPRRKYEIQEGFHGNAHVVFNGSFYYQQRNSDLVVKLDL-TSLKKITTQLPYAGVAAANRLYTTDYNYMDFNVDEVGLWVIYSTYNSN-NTLVAKLDAETLKMQYNFNITLDHHQFGEMFIVCGNLYAIDSGTDKNTQIRYVVDLYKGKLLNTNLPFSNPFSHTTTVGYNPLTVELYSWDKGNALTYPIRYNEQRLISDNS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *..*. :. : **. . . . : : .*: ..:: * ... * *. .:: *. : : : *. *.:: : . . :* ::* *** . :: . **. .**. : .: *. .: *.. * :*. .: : .*. *. : . * : . .:..* ::: :.**. . .. : . .. . *: . * * : * * :*. : *:* *:***.* :*.*: : ::**: *: . * : : : . :.... **: **:*:* :* *:: :* *. * .::* ** . .*. :*: *** ******** ::. :::**:. .*::: .:: .: ::...: *::** **::.* :. .: :.:. * .* . .:**.* :.::: :.**** :*::**: * :** *: : ", "identical_positions": 101, "similar_positions": 185, "identity": "10.58%" }, { "cls_id": "homologset.agr.RGD:620431", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ATQ4-1", "uniprot_id": "A0A8I6ATQ4_RAT", "id": "A0A8I6ATQ4-1", "name": "", "aln": "MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSER--ASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPT--------------------------SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSN---------------ADSSSAYCLPSTRHGFSSYTDSFVPPSGPSN-PMNPAIGNGLSPQVMG-----------LLTNHGGVPHQPQTDYALSPLTGG---------LEPTTTVSASCSQRLEHMKNVDSLP---------------------------------TSQPYCP------------------------PTYSTTGYSMDPVTGYQYGQYGQSKPWTF---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24610-1", "uniprot_id": "PAX3_MOUSE", "id": "P24610-1", "name": "Paired box protein Pax-3", "aln": "MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSER--ASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPT--------------------------SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSN---------------ADSSSAYCLPSTRHGFSSYTDSFVPPSGPSN-PMNPTIGNGLSPQVMG-----------LLTNHGGVPHQPQTDYALSPLTGG---------LEPTTTVSASCSQRLEHMKNVDSLP---------------------------------TSQPYCP------------------------PTYSTAGYSMDPVTGYQYGQYGQSKPWTF---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23760-1", "uniprot_id": "PAX3_HUMAN", "id": "P23760-1", "name": "Paired box protein Pax-3", "aln": "MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSER--ASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPT--------------------------SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSN---------------PDSSSAYCLPSTRHGFSSYTDSFVPPSGPSN-PMNPTIGNGLSPQVMG-----------LLTNHGGVPHQPQTDYALSPLTGG---------LEPTTTVSASCSQRLDHMKSLDSLP---------------------------------TSQSYCP------------------------PTYSTTGYSMDPVTGYQYGQYGQSKPWTF---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09083-1", "uniprot_id": "GSBN_DROME", "id": "P09083-1", "name": "Protein gooseberry-neuro", "aln": "---MDMSSANSLRP------LFAGYP-----FQGQGRVNQLGGVFINGRPLPNHIRLKIVEMAASGVRPCVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPK-VTSPEIETRIDELRKENPSIFSWEIREKLIKEGFAD---PPSTSSISRLLRGSDR----------GS--EDGRKDYTING--ILGGR-------DSDISDTESEPGIPLKRKQRRSRTTFTAEQLEALERAFSRTQYPDVYTREELAQTTALTEARIQVWFSNRRARLRKH----SGGSNSGLSPMNS---GSSNVGVGVGLSGATAPLGYGP--LG-----------VGSMAGYSPAPGTTATGAGMNDGV------HHAAHAPSS------------HHSAATAAAAAHHHTQMGGYDLVQSAAQHGFP----------GGFAQP--------------GHFGSQNYYHQDYSKLTIDDFSK--------LTADSVSKISPS-LHLSDNYSKLEAP---------------SNWSQAA----------YHAAANYN-----------------AHVAQHQLNDYAAAAAHGNPASAYSHPLPTQGQAKYWS--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06601-1", "uniprot_id": "PRD_DROME", "id": "P06601-1", "name": "Segmentation protein paired", "aln": "-MTVTAFAAAMHRP------FFNGYSTMQDMNSGQGRVNQLGGVFINGRPLPNNIRLKIVEMAADGIRPCVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPR-IATPEIENRIEEYKRSSPGMFSWEIREKLIREGVCDRSTAPSVSAISRLVRGRDAPLDNDMSSASGSPAGDGTKASSSCGSDVSGGHHNNGKPSDEDISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVWFSNRRARLRKQHTSVSGGAPGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLDPATVYQQQYDFYGSHANISVSAAAPMASSNLSPGITTTPPHHHQFYNPSANTASYIMPGENGNTTPTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAFGQLPPTPNSLSAVVSGAGVTSSSGANSGADPSQSLANASAGSEELSAALKVESVDLIAASQSQLYGGWSSMQALRPNAPLSPEDSLNSTSSTSQALDVTAHQMFHPYQHTPQYASYPAPGHAHSHHGHPHAPHPHAHPHPQYAGAHPHYPPPSSSAHFMPQNFNAAAFPSPSKVNYTTMPPQPFYPSWY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09082-1", "uniprot_id": "GSB_DROME", "id": "P09082-1", "name": "Protein gooseberry", "aln": "----MAVSALNMTP------YFGGYP-----FQGQGRVNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLRVSHGCVSKILNRFQETGSIRPGVIGGSKPR-VATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAPSVSSISRLLRGSSG----------------SGTSHSIDG--ILGGG--AGSVGSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARVQVWFSNRRARLRKQ-------LNTQQVPSFAP--TSTSFGATPTTSAAPAPN-----------------------MGMSLYSSQSWPSSGA-----------YENHAAYG------------GSVASMSPASSTSGTSSAAHSPVQTQAQQPGTG---------SEFMTS----------------TYGVGSSNATYPSAAYS----------------MPQTPATSAEQLRSQFASAAASG--------------SHHPSTWDS--------YNFAGSFFP------------------PASAAGNHISGYHHQVDQKSSMMTTAPTYPYFGF----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * *:. ********************:** :***** *:******************** *:*********.******: :::*::*.:*:* ::..*.:****** **:. ...* **.*:***::*. . . . : . ..: *: ::**.: *******.****: .*:: *** * **:***:******** : *****:********** **: . ... : * * . . ..: : . . . * . .:: . . . : . .. : :.* : . : : : : :. ", "identical_positions": 140, "similar_positions": 92, "identity": "22.54%" }, { "cls_id": "homologset.agr.RGD:620432", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15173-1", "uniprot_id": "MYOG_HUMAN", "id": "P15173-1", "name": "Myogenin", "aln": "-----------------------------MELYETSPYFYQEPRFYDGEN---YLPVHLQGFEPPGYERT----ELTLSPEAPG-----------------PL----------------EDKGLGTPEHCPG-----------QCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLS----SLNQEERDLRYRGGGGPQPGVPSECSSHSASCSPEWGSALEFSANPGDHLLTADPTDAHNLHSLTSIVDSITVEDVSVAFPDETMPN------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12979-1", "uniprot_id": "MYOG_MOUSE", "id": "P12979-1", "name": "Myogenin", "aln": "-----------------------------MELYETSPYFYQEPHFYDGEN---YLPVHLQGFEPPGYERT----ELSLSPEARG-----------------PL----------------EEKGLGTPEHCPG-----------QCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLS----SLNQEERDLRYRGGGGPQPMVPSECNSHSASCSPEWGNALEFGPNPGDHLLAADPTDAHNLHSLTSIVDSITVEDMSVAFPDETMPN------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20428-1", "uniprot_id": "MYOG_RAT", "id": "P20428-1", "name": "Myogenin", "aln": "-----------------------------MELYETSPYFYQEPHFYDGEN---YLPVHLQGFEPPGYERT----ELSLSPEARG-----------------PL----------------EEKGLGTPEHCPG-----------QCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLS----SLNQEERDLRYRGGGGPSRWYP--VNATPTAPPAVRSGAMHWSLVPTQEIICSQLT-LQVPTTCTPLRPSWTASRWRICLSPSQMKPCPTEIVCQAGCAWEPLSWCQTPPLLQQGPFKWGCPGAQKTALGCHKPDYPPSIHIRLTPSPAREFN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22816-1", "uniprot_id": "MYOD_DROME", "id": "P22816-1", "name": "Myogenic-determination protein", "aln": "MTKYNSGSSEMPAAQTIKQEYHNGYGQPTHPGYGFSAYSQQNPIAHPGQNPHQTLQNFFSRFNAVGDASAGNGGAASISANGSGSSCNYSHANHHPAELDKPLGMNMTPSPIYTTDYDDENSSLSSEEHVLAPLVCSSAQSSRPCLTWACKACKKKSVTVDRRKAATMRERRRLRKVNEAFEILKRRTSSNPNQRLPKVEILRNAIEYIESLEDLLQESSTTRDGDNLAPSLSGKSCQSDYLSSYAGAYLEDKLSFYNKHMEKYGQFTDFDGNANGSSLDCLNLIVQSINKSTTSPIQNKATPSASDTQ------------SPPSSGATAPTSLHVNFKRKCST------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *.* *:* : *:* * .:. *:. * : ::*.:. * ** *:..*.: ** . **.****.**:***:****:***:**:***:******* *** * *************.**:*** *: **. : : :: * . . . .: . . :. : :: : . . . *.. . . ", "identical_positions": 75, "similar_positions": 57, "identity": "20.05%" }, { "cls_id": "homologset.agr.RGD:620433", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88436-1", "uniprot_id": "PAX4_RAT", "id": "O88436-1", "name": "Paired box protein Pax-4", "aln": "---------------------------------------------------MQQDGLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQRQLCAEGLCTQDKAPSVSSINRVLR--ALQEDQR-----------------------------------------------------------------------------LHWTQLRSPAVLAPALPSPHSNCE----APRGPHPGTSH------------------------------------------------------------------------------------------------------------------------------RNRTIFSPGQAEALEKEFQRGQYPDSVVRGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWETQMPGASQDLMVPKDSPGIISAQQSP-----------GSVPSAALPVLEQLNPSFCQLCWGAVPDR-------------------CSSDT------------------------------------------------------------------------------------------------TSQACLQP--YWECHS-LLP----------------------------------------------------VASSSYMEFAWPCLTTHPV----HHLIGGP------------GQAPSTYYLHWP---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32115-1", "uniprot_id": "PAX4_MOUSE", "id": "P32115-1", "name": "Paired box protein Pax-4", "aln": "---------------------------------------------------MQQDGLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLR--ALQEDQS-----------------------------------------------------------------------------LHWTQLRSPAVLAPVLPSPHSNCG----APRGPHPGTSH------------------------------------------------------------------------------------------------------------------------------RNRTIFSPGQAEALEKEFQRGQYPDSVARGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWEAQLPGASQDLTVPKNSPGIISAQQSP-----------GSVPSAALPVLEPLSPSFCQLCCGTAPGR-------------------CSSDT------------------------------------------------------------------------------------------------SSQAYLQP--YWDCQS-LLP----------------------------------------------------VASSSYVEFAWPCLTTHPV----HHLIGGP------------GQVPSTHCSNWP---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43316-1", "uniprot_id": "PAX4_HUMAN", "id": "O43316-1", "name": "Paired box protein Pax-4", "aln": "---------------------------------------------------MHQDGISSMNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVLR--ALQEDQG-----------------------------------------------------------------------------LPCTRLRSPAVLAPAVLTPHSGSE----TPRGTHPGTGH------------------------------------------------------------------------------------------------------------------------------RNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISAQQSP-----------GSVPTAALPALEPLGPSCYQLCWATAPER-------------------CLSDT------------------------------------------------------------------------------------------------PPKACLKP--CWDCGSFLLP----------------------------------------------------VIAPSCVDVAWPCLDASLA----HHLIGGA------------GKATPTHFSHWP---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O18381-1", "uniprot_id": "PAX6_DROME", "id": "O18381-1", "name": "Paired box protein Pax-6", "aln": "MRNLPCLGTAGGSGLGGIAGKPSPTMEAVEASTASHPHSTSSYFATTYYHLTDDECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGDLTPSSLYPCHMTLRPPPMAPAHHHIVPGDGGRPAGVGLGSGQSANLGASCSGSGYEVLSAYALPPPPMASSSAADSSFSAASSASANVTPHHTIAQESCPSPCSSASHFGVAHSSGFSSDPISPAVSSYAHMSYNYASSANTMTPSSASGTSAHVAPGKQQFFASCFYSPWV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: *.:*****:**.***** .***:**.** * ******* *:**************.** :.*: *******:**. **::*:* * * *::*****: :* *.:**:*: *********** * *::* * : .*. * *. :* . .*..** * **** *: .* ::*****:* :*** ..* :** .*** ::************:***: : : *.:: .. :.. * :** **. .::..:: *... .* * **. . :. * * : * * * : :.* : ::.. : . ** *. * . .: * ", "identical_positions": 153, "similar_positions": 95, "identity": "17.85%" }, { "cls_id": "homologset.agr.RGD:620434", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51974-1", "uniprot_id": "PAX8_RAT", "id": "P51974-1", "name": "Paired box protein Pax-8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MPHNSIRS---------------GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFN--LPMDSCVATKSLSPGHTLIPSSAVTP-----PESPQSDSLG--------------------------------------------------STYSINGLLGIAQ------PGSDNKRKMDDSDQDSCR-LSIDSQ--------SSSSGPRKHLRTDTFGQHHLEP--------------LECPFERQHYPEAYASPSHTKGEQGLYPLPLLN----------STLDDGKATLTPSN-----TPLGRNLSTHQTYPVVAD-----PHSPYAIKQETP---------------------------------ELSSSSSTPSSLSSSAFLDLQQV-----------GSGGPAGASVPPFNAFS-----HAASVYGQFTGQALLSGREMVGPTLPGYP----PHIPTSGQ----------------------GSYAS-----------SAIAGMVAGSEYSGNAYSHTPYASYSEAWRFPNSS-LLSSPYYYSSTTRPS------APPTSATAFDHL-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00288-1", "uniprot_id": "PAX8_MOUSE", "id": "Q00288-1", "name": "Paired box protein Pax-8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MPHNSIRS---------------GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFN--LPMDSCVATKSLSPGHTLIPSSAVTP-----PESPQSDSLG--------------------------------------------------STYSINGLLGIAQ------PGNDNKRKMDDSDQDSCR-LSIDSQ--------SSSSGPRKHLRTDTFSQHHLEA--------------LECPFERQHYPEAYASPSHTKGEQGLYPLPLLN----------SALDDGKATLTSSN-----TPLGRNLSTHQTYPVVAD-----PHSPFAIKQETP---------------------------------ELSSSSSTPSSLSSSAFLDLQQV-----------GSGGPAGASVPPFNAFP-----HAASVYGQFTGQALLSGREMVGPTLPGYP----PHIPTSGQ----------------------GSYAS-----------SAIAGMVAGSEYSGNAYSHTPYSSYSEAWRFPNSS-LLSSPYYYSSTSRPS------APPTSATAFDHL-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06710-1", "uniprot_id": "PAX8_HUMAN", "id": "Q06710-1", "name": "Paired box protein Pax-8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MPHNSIRS---------------GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFN--LPMDSCVATKSLSPGHTLIPSSAVTP-----PESPQSDSLG--------------------------------------------------STYSINGLLGIAQ------PGSD-KRKMDDSDQDSCR-LSIDSQ--------SSSSGPRKHLRTDAFSQHHLEP--------------LECPFERQHYPEAYASPSHTKGEQGLYPLPLLN----------STLDDGKATLTPSN-----TPLGRNLSTHQTYPVVAD-----PHSPFAIKQETP---------------------------------EVSSSSSTPSSLSSSAFLDLQQV-----------GSG------VPPFNAFP-----HAASVYGQFTGQALLSGREMVGPTLPGYP----PHIPTSGQ----------------------GSYAS-----------SAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFPNSS-LLSSPYYYSSTSRPS------APPTTATAFDHL-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O16117-1", "uniprot_id": "O16117_DROME", "id": "O16117-1", "name": "", "aln": "MLIMDIQTSTHHIHGLGTHELQHRILHPHILHSTQEETLNTSTGQLEHDSQHLQQHHLTHHQQQDVSPTLHNLQNTRTGDSLSTTINTNQNQHGHQHLSGSNMYTSSQMEDKSKANKYDEYSSRTLSNISDANTTPSANNFITQSQGIEWITAMNDIQNGAEDSHSSQGSISGDGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNKAAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVNTNVSASASVHASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHNNNNNSSVNNNNNTESSCKRKRIEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIWSGKWCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDSITTISQTQSSIYTPAIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALAFDGNYTSMTSLENCSSLVGQEHIVMPESSDSNTLCPISTRIVPDITETNSTRVKEPLTNSDGCSEDNNKEPEKSNSSQSSDHIASPHLHHIGEEQLRGNRRSNLNASTHPSSLIPLQPSGGSSLLNINPSENRSDVELNLSNNVGLYSTPTVLPSFNHYSAGCSSVVPGSDYAYNP-AYTQYGGAYGSYGYGTGSGLINSSYYYESGQTQSPLTHDLRSPLVATRANSLASAASPGSGSACTKSESSDIFLA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.*:. ****:*****.********:*******:***:**********************.*******::.************* **: *.:***:****************.:*.:*.**********:*.*. : : :. .::**. ** * :. *:.* *:* . : *****:*** : ..: . : ::. :.**: *::: *... *: * .::. .:* . * . : . . . ...:: :..:*: . *: . * * *. :*:: :: ..:* .:.* . *:*. *. :*:::* **.*.* ..:*: . *: :. ..* * :: . * ** : :. *: * *.. . . . :* * *:.*. * *:: :. :.:*.**:*: *. .:* *.. :: : ..* *:.*.***.* * .* ** : * ", "identical_positions": 184, "similar_positions": 159, "identity": "21.78%" }, { "cls_id": "homologset.agr.RGD:620435", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02384-1", "uniprot_id": "SOS2_MOUSE", "id": "Q02384-1", "name": "Son of sevenless homolog 2", "aln": "-------------------------------------------------------------MQQAPQPYEFFSEENSPK-------------WR--------GLLVPALR--------------------------------------------KVQEQVHPTLSANEESLYYIEELIFQLLNKLCMA-QPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLK-EVLGYKVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDDDIGLVSLCEDEPCSSGELNYYDLVR-TEIAEERQYLRELNMIIKVFREAFLLDRKLFKPSEIEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILAPEFNDHFSKLMARPAVALHFQSIADGFKEAVRYVLP-RLMLVPVYHCWHYFELLKQLKACSEEQEDKECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCLFYNRQLRSKHLAIKKMNEIQKNIDGWEGKDIG--QCCNEFIMEGPLTRIGAKH----ERHIFLFDG---LMISCKPN-HGQTRLPGYSSAEYRLKEKFVMRKIQICDKEDACEYRHAFELVSKDENSVIFAAKSAE--------------EKNNWMAALISLHYRSTLDR------MLDSVLLKEENEQPLRLP------------SPDMYRFVVTDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLN-LLIERFEIPEPEPTEADKLALEKG----------------EQPISADLKRFRKEYVQPVQLRVLNVFRHWVEHHYYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIKRKKQ------AQANGISHNITFESSPPPVEWHISRTGQFETFDLMTLHPIEIAR-QLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLT--LWFEKCIVEAENFEERVAVLSRIVEILQVFQDLN----NFNGVLEIVSAVNSVSVYRLDHTFEALQERKR---RILDDAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNSDFLKRKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRTEPEMRRFFENLNPMG--ILSEKEFTDYLFNKSLEIEPRNCKQPPRFPRKS-TFSLKSPGIRPNAGRHGSTSGTLRGHPTPLEREPYKISFSRIAETELESTVSAPTSPNTPSTPPVSASS--------------DHSVFLDVDLN-----------------------------------------------SSCGSNTIFAPVL--------LPHSKTFFSSCGS----LHKLSEEP--------------------------------------------------------------------------LIPPPLPPRKKFDHDALNSKGAVKSDDDPPAIPPR--QPPPPKVKPRVPVLMG------------------------------------------------TFDGPVPSPPPPPPRDPLPDTPPPVPLRPPE-----------HFINCPFNLQPPP-----------LGHPHRDPDWLRDVSTCPNSPSTPPTTPSPRIPRSCHLLSSSHSSLAHLPAPPVPPR------QNSSPLLPKLPPKTYKRELSHPPLYRLPLLENAETPQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M1M3-1", "uniprot_id": "A0ABK0M1M3_RAT", "id": "A0ABK0M1M3-1", "name": "", "aln": "--------------------MSFSPHIRVLPSRAAVTAPGSPRAARIRFVCRDSDAAAECVWNSRPAPAHVPRRDRLPSRPPGPAPG----AWARSAARMLGAGLLPRLGRASAGPSRAAAAGTRRSAAARGAGGAASAVHAGHARPLGPEGPLEVQEQVHPTLSANEESLYYIEELIFQLLNKLCLA-QPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLK-EVLGYKVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDDDIGLVSLCEEEPCSSGELNYYDLVR-TEIAEERQYLRELNMIIKVFREAFLSDKKLFKSSEIEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILAPEFNDHFSKLMARPAVALHFQSIADGFKEAVRYVLP-RLMLVPVYHCWHYFELLKQLKACSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCLFYNRQLRSKHLAIKKMNEIQKNIDGWEGKDIG--QCCNEFIMEGPLTRIGAKH----ERHIFLFDG---LMISCKPN-HCQTRLPGYSSAEYRLKEKFVMRKIQICDKEDACEYKHAFELVSKDENSVIFAAKSAE--------------EKNNWMAALISLHYRSTLDR------MLDSVLLKEENEQPLRLP------------RPDVYRFVVTDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLS-LLIERFEIPDPEPTEADKLALEKG----------------EQPISADLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLEAFISSVRGKAMKKWVESIAKIIKRKKQ------AQANGVSHNITFESPPPPVEWHISRAGQSETFDLMTLHPIEIAR-QLTLLESDLYRRVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLT--LWFEKCIVEAENFEERVAVLSRIVEILQVFQDLN----NFNGVLEIVSAVNSVSVYRLDHTFEALQERKR---RVLDDAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNSDFLKRKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRTEPEMRRFFENLNPMG--LLSEKEFTDYLFNKSHEIEPRNCKQPPRFPRKS-TFSLKSPGIRPNASRHGSTSGTFRGHPTPLEREPYKISFSRIAETELESTVSAPTSPNTPSTPPVSASS--------------DHSVFLDVDLN-----------------------------------------------SSCGSNTIFAPVL--------LPHSKSFFSSCGS----LHKLSEEP--------------------------------------------------------------------------LVPPPLPPRKKFDHDAPNSKGAMKSDDDPPAIPPR--QPPPPKVKPRAPVLTG------------------------------------------------TFEGPVPSPPPPPPRDPLPDTPPPVPLRPPE-----------HFINCPFNLQPPP-----------LGHPHRDPDWLRDVSTCPNSPSTPPPTPSPRIPRRCHLPSPSHNNLAHPPAPPVPPR------QNSSPHLPKLPPKTYKRELSHPPLYRLPLFENAETPQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07890-1", "uniprot_id": "SOS2_HUMAN", "id": "Q07890-1", "name": "Son of sevenless homolog 2", "aln": "-------------------------------------------------------------MQQAPQPYEFFSEENSPK-------------WR--------GLLVSALR--------------------------------------------KVQEQVHPTLSANEESLYYIEELIFQLLNKLCMA-QPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLK-EVLGYKVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD-IGLVSLCEDEPSSSGELNYYDLVR-TEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDIEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDILSPEFHEHFNKLMARPAVALHFQSIADGFKEAVRYVLP-RLMLVPVYHCWHYFELLKQLKACSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYSHQLRSKHLAIKKMNEIQKNIDGWEGKDIG--QCCNEFIMEGPLTRIGAKH----ERHIFLFDG---LMISCKPN-HGQTRLPGYSSAEYRLKEKFVMRKIQICDKEDTCEHKHAFELVSKDENSIIFAAKSAE--------------EKNNWMAALISLHYRSTLDR------MLDSVLLKEENEQPLRLP------------SPEVYRFVVKDSEENIVFEDNLQSRSGIPIIKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLS-LLIERFEIPEPEPTDADKLAIEKG----------------EQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVRGKAMKKWVESIAKIIRRKKQ------AQANGVSHNITFESPPPPIEWHISKPGQFETFDLMTLHPIEIAR-QLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLT--LWFEKCIVEAENFEERVAVLSRIIEILQVFQDLN----NFNGVLEIVSAVNSVSVYRLDHTFEALQERKR---KILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMG--SASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKS-TFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASS--------------DLSVFLDVDLN-----------------------------------------------SSCGSNSIFAPVL--------LPHSKSFFSSCGS----LHKLSEEP--------------------------------------------------------------------------LIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPR--QPPPPKVKPRVPVPTG------------------------------------------------AFDGPLHSPPPPPPRDPLPDTPPPVPLRPPE-----------HFINCPFNLQPPP-----------LGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLSSSQNNLAHPPAPPVPPR------QNSSPHLPKLPPKTYKRELSHPPLYRLPLLENAETPQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P26675-1", "uniprot_id": "SOS_DROME", "id": "P26675-1", "name": "Protein son of sevenless", "aln": "-----------MFSGPSGHAHTISYGGGIGLGTGGGGGSGGSGSGSQGGGGGIGIGGGGVAGLQDCDGYDFTKCENAAR-------------WR--------GLFTPSLK--------------------------------------------KVLEQVHPRVTAKEDALLYVEKLCLRLLAMLCAKPLPHSVQDVEEKVNKSFPAPIDQWALNEAKEVINSKKRKS--VLPTEKVHTLLQKDVLQYKIDSSVSAFLVAVLEYISADILKMAGDYVIKIAHCEITKEDIEVVMNADRVLMDMLNQSEAHILPSPLS-LPAQRASATYEETVK-ELIHDEKQYQRDLHMIIRVFREELV--KIVSDPRELEPIFSNIMDIYEVTVTLLGSLEDVIEMSQEQS-APCVGSCFEELAEAEEFDVYKKYAYDVTSQASRDALNNLLSKPG-ASSLTTAGHGFRDAVKYYLP-KLLLVPICHAFVYFDYIKHLKDLSSSQDDIESFEQVQGLLHPLHCDLEKVMASLSKERQ------VPVSGRVR-RQLAIERTRELQMKVEHWEDKDVG--QNCNEFIREDSLSKLGSGKRIWSERKVFLFDG---LMVLCKANTKKQTPSAGATAYDYRLKEKYFMRRVDINDRPDSDDLKNSFELAPRMQPPIVLTAKNAQ--------------HKHDWMADLLMVITKSMLDR------HLDSILQDIERKHPLRMP------------SPEIYKFAVPDSGDNIVLEE--RESAGVPMIKGATLCKLIERLTYHIYADPTFVRTFLTTYRYFCSPQQLLQ-LLVERFNIPDPSLVYQDTGTAGAGGMGGVGGDKE-----HKNSHREDWKRYRKEYVQPVQFRVLNVLRHWVDHHFYDFEKDPMLLEKLLNFLEHVNGKSMRKWVDSVLKIVQRKNE------QEKSNKKIVYAYGHDPPPIEHHLSVPN--DEITLLTLHPLELAR-QLTLLEFEMYKNVKPSELVGSPWTKKDKEVKSPNLLKIMKHTTNVT--RWIEKSITEAENYEERLAIMQRAIEVMMVMLELN----NFNGILSIVAAMGTASVYRLRWTFQGLPERYR---KFLEECRELSDDHLKKYQERLRSINPPCVPFFGRYLTNILHLEEGNPDLLAN--TELINFSKRRKVAEIIGEIQQYQNQPYCLNEESTIRQFFEQLDPFN--GLSDKQMSDYLYNESLRIEPRGCKTVPKFPRKWPHIPLKSPGIKPRRQNQTNSSSKLSNSTSSVAAAAAASSTATSIATASAPSLHASSIMDAPTAAAANAGSGTLAGEQSPQHNPHAFSVFAPVIIPERNTSSWSGTPQHTRTDQNNGEVSVPAPHLPKKPGAHVWANNNSTLASASAMDVVFSPALPEHLPPQSLPDSNPFASDTEAPPSPLPKLVVSPRHETGNRSPFHGRMQNSPTHSTASTVTLTGMSTSGGEEFCAGGFYFNSAHQGQPGAVPISPHVNVPMATNMEYRAVPPPLPPRRKERTESCADMAQKRQAPDAPTLPPRDGELSPPPIPPRLNHSTGISYLRQSHGKSKEFVGNSSLLLPNTSSIMIRRNSAIEKRAAATSQPNQAAAGPISTTLVTVSQAVATDEPLPLPISPAASSSTTTSPLTPAMSPMSPNIPSHP-----------VESTSSSYAHQLRMRQQQQQQTHPAIYSQHHQHHATHLPHHPHQHHSNPTQSRSSPKEFFPI-ATSLEGTPKLPPKPSLSANFYNNPDKGTMFLYPSTNEE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04821-1", "uniprot_id": "CDC25_YEAST", "id": "P04821-1", "name": "Cell division control protein 25", "aln": "MSDTNTSIPNTSSAREAGNASQTPSISSSSNTSTTTNTESSSASLSSSPSTSELTSIRPIGIVVAAYDFNYPIKKDSSSQLLSVQQGETIYILNKNSSGWWDGLVIDDSNGKVNRGWFPQNFG------------------------------RPLRDSHLRKHSHPMKKYSSSKSSRRSSLNSLGNSAYLHVPRNPSKSRRGSSTLSASLSNAHNAETSSGHNNTVSMNNSPFSAPNDASHITPQSSNFNSNASLSQDMTKSADGSSEMNTNAIMNNNETNLQTSGEKAGPPLVAEETIKILPLEEIEMIINGIRSNIASTWSPIPLITKTSDYKLVYYNKDLDIYCSELPLISNSIMESDDICDSEPKFPPNDHLVNLYTRDLRKNANIEDSSTRSKQSESEQNRSSLLMEKQDSKETDGNNNSINDDDNNNENNKNEFNEAGPSSLNSLSAPDLTQNIQSRVVAPSRSSILAKSDIFYHYSRDIKLWTELQDLTVYYTKTAHKMFLKENRLNFTKYFDLISDSIVFTQLGCRLMQHEIKAKSCSKEIKKIFKGLISSLSRISINSHLYFDSAFHRKKMDTMNDKDNDNQENNCSRTEGDDGKIEVDSVHDLVSVPLSGKRNVSTSTTDTLTPMRSSFSTVNENDMENFSVLGPRNSVNSVVTPRTSIQNSTLEDFSPSNKNFKSAKSIYEMVDVEFSKFLRHVQLLYFVLQSSVFSDDNTLPQLLPRFFKGSFSGGSWTNPFSTFITDEFGNATKNKAVTSNEVTASSSKNSSISRIPPKMADAIASASGYSANSETNSQIDLKASSAASGSVFTPFNRPSHNRTFSRARVSKRKKKYPLTVDTLNTMKKKSSQIFEKLNNATGEHLKIISKPKSRIRNLEINSSTYEQINQNVLLLEILENLDLSIFINLKNLIKTPSILLDLESEEFLVHAMSSVSSVLTEFFDIKQAFHDIVIRLIMTTQQTTLDDPYLFSSMRSNFPVGHHEPFKNISNTPLVKGPFHKKNEQLALSLFHVLVSQDVEFNNLEFLNNSDDFKDACEKYVEISNLACIIVDQLIEERENLLNYAARMMKNNLTAELLKGEQEKWFDIYSEDYSDDDSENDEAIIDDELGSEDYIERKAANIEKNLPWFLTSDYETSLVYDSRGKIRGGTKEALIEHLTSHELVDAAFNVTMLITFRSILTTREFFYALIYRYNLYPPEGLSYDDYNIWIEKKSNPIKCRVVNIMRTFLTQYWTRNYYEPGIPLILNFAKMVVSEKIPGAEDLLQKINEKLINENEKEPVDPKQQDSVSAVVQTTKRDNKSPIHMSSSSLPSSASSAFFRLKKLKLLDIDP-----------------------------------------YTYATQLTVLEHDLYLRITMFECLDRAWGTKYCNMGGSPNITKFIANANTLTN---------------------------------------------------------------FVSHTIVKQADVKTRSKLTQYFVTVAQHCKELNNFSSMTAIVSALYSSPIYRLKKTWDLVSTE--------------------------------------SKDLLKNLNNLMDSKRNFVKYRELLRSVTDVACVPFFG---------VYLSDLTFTFVGNPDFLHNSTNIINFSKRTKIANIVEEIISFKRFHYKLKRLDDIQTVIEASLENVPHIEKQYQLSLQVEPRSGNTKGSTHASSASGTKTAKFLSEFTDDKNGNFLKLGKKKPPSRLFR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . : :. : . :. * * : :: .: . : . . . :*: .: . * . : : :.: .* . . .:. :: . : : : : :. : *:..: : :. : . . .. . . : .: : :: : :: : .. .:: ::: : . :** :.:.. .* : : : : * :. * .: . : *. : : . : * : ::. . : ::. :* .. * : .: : * . .:: : : : . :: :. . .:. :. : . : :. . *.: :* : . : .. .* . .:. : .: : . :. . .:: . .. : .. . : :: : . * : *:* : . :. * :* . * . : : : . . *..:: :: ::: : : . : . *. : .... . :. *: *. . . . .. . :. *::: :. .: . :: *: .: ** .: :. ::: :.: :: :.: . . : . : : : * : :. * ::.: . : ::.:. : ** . : *::::: . : :: : .:.. ::::. : *: : : . :: : : . *: . : . *: * ::. .: :.* : : :*:* : :.. .: **:. . :::.: :: . * . : :: . : * .: . :: ::* *: * : * : .*** . . : .. . . :: . .. : : : : : * : . : *: .. . : .* * :. : .::.. .. : . : : :. * : . .: * . : . . : : .: *: . . . . : .. . ", "identical_positions": 63, "similar_positions": 422, "identity": "3.56%" }, { "cls_id": "homologset.agr.RGD:620436", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01216-1", "uniprot_id": "GLHA_MOUSE", "id": "P01216-1", "name": "Glycoprotein hormones alpha chain", "aln": "MDYYRKYAAVILVMLSMFLHILHSLPDGDFIIQGCPECKLKENKYFSKLGAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNARVENHTECHCSTCYYHKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11962-1", "uniprot_id": "GLHA_RAT", "id": "P11962-1", "name": "Glycoprotein hormones alpha chain", "aln": "MDCYRRYAAVILVMLSMVLHILHSLPDGDLIIQGCPECKLKENKYFSKLGAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKSFTKATVMGNARVENHTDCHCSTCYYHKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P01215-1", "uniprot_id": "GLHA_HUMAN", "id": "P01215-1", "name": "Glycoprotein hormones alpha chain", "aln": "MDYYRKYAAIFLVTLSVFLHVLHSAPD----VQDCPECTLQENPFFSQPGAPILQCMGCCFSRAYPTPLRSKKTMLVQKNVTSESTCCVAKSYNRVTVMGGFKVENHTACHCSTCYYHKS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **:***::** **:.**:*** ** :*.****.*:** :**: **** ************** ******** **:***:******::.:.****. :***** ***********", "identical_positions": 85, "similar_positions": 21, "identity": "70.83%" }, { "cls_id": "homologset.agr.RGD:620437", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35790-1", "uniprot_id": "PIGL_RAT", "id": "O35790-1", "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "aln": "------------------------------------------------MEVVGLLCVAVAVLT-----WGFLRVWNSAERMRSP--------------EQAGLPGAGS--------------------------------RALVVIAHPDDEAMFFAPTILGLARLK---QQVSLLCFSSGNYYNQGEIRKKELLQSCAVLGIPPSRVMIIDKREFPDDPEVQWDTEHVASTILQHIHANATDL---VVTFDAEGVSGHSNHIALYKAVRALHSGGKLPEG--------CSVLTLQSVN--VLRKY----VFLLDLPWTLLSPQGVLFVLTSKEVAQAK-----------------KAMSCHRSQLLWFRHLYTVFSRYMSVNSLQLL--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SX19-1", "uniprot_id": "PIGL_MOUSE", "id": "Q5SX19-1", "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "aln": "------------------------------------------------MELVGFLCVAVAVLT-----WGFLRVWNSAERMRSP--------------EQAGLPGAGS--------------------------------RALVVIAHPDDEAMFFAPTMLGLARLE---QQVSLLCFSSGNYYNQGEIRKKELLQSCAVLGIPPSRVMIIDKRDFPDDPEVQWDTELVASTLLQHIHANGTDL---VVTFDAEGVSGHSNHIALYKAVRALHSGGKLPKG--------CSVLTLQSVN--ALRKY----AFLLDLPWTLLSPQDVLFVLTSKEVAQAK-----------------KAMSCHRSQLLWFRYLYVLFSRYMRINSLRFL--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2B2-1", "uniprot_id": "PIGL_HUMAN", "id": "Q9Y2B2-1", "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "aln": "------------------------------------------------MEAMWLLCVALAVLA-----WGFLWVWDSSERMKSR--------------EQGGRLGAES--------------------------------RTLLVIAHPDDEAMFFAPTVLGLARLR---HWVYLLCFSAGNYYNQGETRKKELLQSCDVLGIPLSSVMIIDNRDFPDDPGMQWDTEHVARVLLQHIEVNGINL---VVTFDAGGVSGHSNHIALYAAVRALHSEGKLPKG--------CSVLTLQSVN--VLRKY----ISLLDLPLSLLHTQDVLFVLNSKEVAQAK-----------------KAMSCHRSQLLWFRRLYIIFSRYMRINSLSFL--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P3K2-1", "uniprot_id": "A0A8M1P3K2_DANRE", "id": "A0A8M1P3K2-1", "name": "N-acetylglucosaminylphosphatidylinositol deacetylase", "aln": "---------------------------------------------MFVFFTISFVLVAYAVFIKFVY-YRHSQLWPHALNKISTPLYTVGNSRFCPAQERSGALFPNSEDENPRE------------------------TRALIVTAHPDDECMFFAPTVLRLVESR---AAVCLLCLSTGNYNNQGLQRKKELLDSCAVLGIPANHVSIIDDKELPDDPAVQWSTALISSLILKHIQNYAISL---VLTFDGRGVSGHANHIAIYKTLSHLASAGRIHEG--------CQIFSLHSIS--IIRKY----LSILELPVSWLLPSDFCCIIGREDYKRAK-----------------KAMLCHRSQLLWFRRLYILFSRYMFVNTFQAITAETKNVKIY----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K6Q5-1", "uniprot_id": "A0A0B4K6Q5_DROME", "id": "A0A0B4K6Q5-1", "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "aln": "MRFNWLSEYVASISSSIASTSPWRQLQQQVQQLVPNPQAIYCRIRSSSAEALEHVLIACAVYLLVCLGLYKLTFWLSGAGSGSGLDAHHNGNDTSNAGSGEGAELNPSSDGNRSPGGLKQALQSGIRLRSVRLPKTACMERVLLITAHPDDECMFFGPLIYSLTQRQG--CQVYILCLSNGNFEHKAKVRRQELWRSCSKLGIPESNIVLMNATNLPDDPYVDWRPDAVASLILHTIESLDIQA---IFTFDRDGVSSHPNHCAVYYAAASLCLANLLPKD--------CKFYTLDSIN--VVRKY----LSILDLLCTCFMST-HRCILNWKEAAIVR-----------------SAMMEHQSQMRWFRWLYIYFSRYMFINSMRQINLSDVELEMQIHDN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23797-1", "uniprot_id": "GPI12_YEAST", "id": "P23797-1", "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "aln": "-------------------------------------------MKMLRRTKVNFSKLLYKITKLAIVLTILYIYFTPKIVSRNN--------------ASLQHIFPHKYG----------------------------DYEINLVIAHPDDEVMFFSPIISQLNSYFPRTVPFNIICLSKGNAEGLGETRVRELNESAALL-LHNERAVSVQVMDFQDGMDEIWDIDSITSSLSQKIDIKNHNLNQIIVTFDSYGVSNHINHKSCYAAVKKLVDDYAQPKTKRNEQPPHVTALYLRSYKNNIVLKYNSFIWEILKILYDLISPFRRIIQALPPNTAAEKDKLSLMNTHAQYVLAFATMLNAHESQVVWFRYGWWIFSRFVFVNEFDVYTY------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . . . :: ****** ***.* : * . ::*:* ** . * :** *. * : . :: :: *. * :: : : *. . :.*** ***.* ** : * : * : * * . : ** :*.: : . : : . : *.**: *** : ***:: :* : ", "identical_positions": 49, "similar_positions": 55, "identity": "12.19%" }, { "cls_id": "homologset.agr.RGD:620438", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51840-1", "uniprot_id": "GUC2E_RAT", "id": "P51840-1", "name": "Retinal guanylyl cyclase 1", "aln": "--------------------MSAWLLPAGG-----FPGAGFCIPAWQSRSSLSRVLRWPGPGLPGLLLLLLLPSPS---AFSAVFKVGVLGPWACDPIFARARPDLAARLATDRLNRDLALDGGPWFEVTLLPEPCLTPGS---------------------------------------------------------------------------------------------LGAVSSALTRVSGLVGPVN------------------------------------------------------PAACRPAELLAQEAGVALVPWGCPGTRAAGTTAP----AVTPAADALYVLLKAFRWARVALITAPQDLWVEAGRALSTALRARGLPVALVTSMVPSDLSGAREALRRIRDGPRVRVVIMVMHSVLLG-----------GEEQRYLLEAAEELGLTDGSLVFLPFDT----------LHYALSPGPEALAAFVNSSKLRRAHDAVLTLTRRCPPGGSVQDSLRRAQEHQELPLDLDLKQVS----PLFGTIYDAVFLLAGGVTRARAAVGGGWVSGASVARQMREAQVFGF-----CGILGRTEEPSFVLLDTDAAGERLFTTHLLDP-----VLGSLRSAGTPVHFPRGAPAPGPDPSCWFDPDVICNGGVEPGLVFVGFLLVIVVGLTGAFLAHYLRHR--------------------LLHMQMVSG-----PNKIILTLEDVTFLHPQGG----SSRKVAQGSRSSLATRSTSDIRSVPSQPQESTNIGLYEGDWVWLKKFP-GEHHMAIRPATKMAFSKLRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQRDIKLDWMFKSSLLLDLIKGMRYLHHR-GVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQLWTAPELLRDPALERR---------GTLAGDVFSLGIIMQEVVCRSTPYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPMECIQLMAQCWAEHPELRPSMDLTFDLFKGINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGSFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNMSTVRILRALDQGFQMECRGRTELKGKGVEDTYWLVGRVGFNKPIPKPP------DLQPGASNHGISLQEIPPERRKKLEKARPGQFTGK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52785-1", "uniprot_id": "GUC2E_MOUSE", "id": "P52785-1", "name": "Retinal guanylyl cyclase 1", "aln": "--------------------MSAWLLPAGG-----LPGAGFCVPARQSPSSFSRVLRWPRPGLPGLLLLLLLPSPS---ALSAVFKVGVLGPWACDPIFARARPDLAARLAANRLNRDFALDGGPRFEVALLPEPCLTPGS---------------------------------------------------------------------------------------------LGAVSSALSRVSGLVGPVN------------------------------------------------------PAACRPAELLAQEAGVALVPWGCPGTRAAGTTAP----AVTPAADALYVLLRAFRWARVALITAPQDLWVEAGRALSTALRARGLPVALVTSMETSDRSGAREALGRIRDGPRVRVVIMVMHSVLLG-----------GEEQRYLLEAAEELALTDGSLVFLPFDT----------LHYALSPGPEALAAFVNSSQLRRAHDAVLTLTRRCPPGGSVQDSLRRAQEHQELPLDLNLKQVS----PLFGTIYDAVFLLAGGVKRARTAVGGGWVSGASVARQVREAQVSGF-----CGVLGRTEEPSFVLLDTDASGEQLFATHLLDP-----VLGSLRSAGTPMHFPRGGPAPGPDPSCWFDPDVICNGGVEPGLVFVGFLLVIGMGLTGAFLAHYLRHR--------------------LLHMQMASG-----PNKIILTLEDVTFLHPPGG----SSRKVVQGSRSSLATRSASDIRSVPSQPQESTNVGLYEGDWVWLKKFP-GEHHMAIRPATKTAFSKLRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFKSSLLLDLIKGMRYLHHR-GVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQLWTAPELLRDPSLERR---------GTLAGDVFSLAIIMQEVVCRSTPYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPMECIQLMTQCWAEHPELRPSMDLTFDLFKSINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGAHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGSFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNMSTVRILRALDQGFQMECRGRTELKGKGIEDTYWLVGRLGFNKPIPKPP------DLQPGASNHGISLQEIPPERRKKLEKARPGQFTGK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02846-1", "uniprot_id": "GUC2D_HUMAN", "id": "Q02846-1", "name": "Retinal guanylyl cyclase 1", "aln": "--------------------MTACARRAGG-----LPDPGLCGPAWWAP-SLPRLPR-ALPRLP-LLLLLLLLQPP---ALSAVFTVGVLGPWACDPIFSRARPDLAARLAAARLNRDPGLAGGPRFEVALLPEPCRTPGS---------------------------------------------------------------------------------------------LGAVSSALARVSGLVGPVN------------------------------------------------------PAACRPAELLAEEAGIALVPWGCPWTQAEGTTAP----AVTPAADALYALLRAFGWARVALVTAPQDLWVEAGRSLSTALRARGLPVASVTSMEPLDLSGAREALRKVRDGPRVTAVIMVMHSVLLG-----------GEEQRYLLEAAEELGLTDGSLVFLPFDT----------IHYALSPGPEALAALANSSQLRRAHDAVLTLTRHCPSEGSVLDSLRRAQERRELPSDLNLQQVS----PLFGTIYDAVFLLARGVAEARAAAGGRWVSGAAVARHIRDAQVPGF-----CGDLGGDEEPPFVLLDTDAAGDRLFATYMLDP-----ARGSFLSAGTRMHFPRGGSAPGPDPSCWFDPNNICGGGLEPGLVFLGFLLVVGMGLAGAFLAHYVRHR--------------------LLHMQMVSG-----PNKIILTVDDITFLHPHGG----TSRKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFP-GDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDLLAQREIKLDWMFKSSLLLDLIKGIRYLHHR-GVAHGRLKSRNCIVDGRFVLKITDHGHGRLLEAQKVLPEPPRAEDQLWTAPELLRDPALERR---------GTLAGDVFSLAIIMQEVVCRSAPYAMLELTPEEVVQRVRSPPPLCRPLVSMDQAPVECILLMKQCWAEQPELRPSMDHTFDLFKNINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELELEKQKTDRLLTQMLPPSVAEALKTGTPVEPEYFEQVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGTFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNLSTVGILRALDSGYQVELRGRTELKGKGAEDTFWLVGRRGFNKPIPKPP------DLQPGSSNHGISLQEIPPERRRKLEKARPGQFS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BCH5-1", "uniprot_id": "A0A8M2BCH5_DANRE", "id": "A0A8M2BCH5-1", "name": "Guanylate cyclase", "aln": "--------MNDHTSFLCQSHHPRWQTQSSAGKRRRKQSSSQKSETPASPVSSSPVLRSHSWWGNCFLLPLVMLSYFPCEAWGTTFKIAIVGPWACDPMYSKALPDLAARLAMSRINKDPELNKGYWYDYTVINEDCSSSRG---------------------------------------------------------------------------------------------LARFAELEGYGSAFLGPAN------------------------------------------------------PGYCTAATLLAKNWNKGILSWGCLKAEMDEEMYPTFLRPLPLSSRVLFSVLRFFRWAHVGIVTAEGDMWEATGHELAASLRALGLPVGKVVTMEQ-DKEGPRQALQAIRDTDRVRVVIMCMHSALIG-----------GEEQYQLLTTALEMRMIDRGYIFIPYDT----------LLYSLPYENVKYPILANDSKLRRAYDGVLTVTMDQ-GEQNFYEAFNAAQESFEIRGSTSAEEVTRWVSPFFGTIYNMIYYTAMAAEQSRASSGGRWVSGDLLSQNEGGFEFDGFNQRISGGTNGEGMQVRYAVLDSDGSGSSLYRTHALEASHTYGKYGGLKYLGKSIHFA--GASPSSDANCWFSPYIACSGGLDGVTLFFLLMFFIVLIAGAGILFLQVRKYGAGG----------------FFGAFIGGGG---SPTKIVLTLDDLVFINTTLSRRKLNDESMLKSQLDVKTPRHSVSGRSYITSTPETSNVAVFEGDWVWLKKCPCADSITEISESTQTIFVKLRDMRHENLNLFLGLFMD----------TGIFGIVTEHCTRGSLEDLLNNEEMRLDWMFKSSLLLDLIRGMKYLHNR-GIIHGRLKSRNCVVDGRFVLKVTDYGFNEILNCQNIILEDNAPEDQFWTAPEILRNPDLKKK---------GTYPGDVYSFSIIMQEVISRCAPFCMLDMPPEEIIEKVRSPPPLCRPTVSMDEAPLDVIQLMKQAWSEEPEQRPTFEDIFRQFKSMNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEVERQKTDALLAQMLPKSVALALKTGKPVKPEHFAEVTLYFSDIVGFTTISALSEPIEVVDLLNDLYTHFDGIIAIHDVYKVETIGDAYMVASGVPNRNGTRHAAEMANMSLDILHCIGTFKMRHMPDVKVKIRIGLHSGPVVAGVVGLKMPRYCLFGDTVNTASRMESTGLPYRIHVNQSTVDVLNSLKLGYKIDTRGRTELKGKGVEETFWLVGRDGFDKPLPIPP------DLTPGASNHGISLDEIPTDRRQKFLDRQKRMGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A4D6K026-1", "uniprot_id": "A0A4D6K026_DROME", "id": "A0A4D6K026-1", "name": "Guanylate cyclase", "aln": "MKLTTCQIAKVFPLLTAFFFLNSPSAASLSFGLSPTFASASASSSLSSSSSSSSHFHSEKPLHSDVLVLRAAKPSRAIATSADAATRSVPASAAETTLGSKSIWPTAIQTKSPRNAREAGRHKRQMQKPAIQQQPLQQQQQRINPPQQKRQQQQQQQQQVQHQAQRVGVLIPPSLHVDLTHVQQGFQNFLDFFQLHLFNVTVDFLRDVDLSGFIKLLELPKYTSVIKTLNAGIMVASHVDVDQNSTIYIGTPSQPRQQHRLHSKQEQEPHRHHHEDSKAKQFPAGEEESHSSGETEENHWNDARIFSGHCHQLAEQLALDFNKTVVLWPCPRMKISSNFLP----SFEAISLAVQSISTKLNWSQVDIYIGDDNWGLGLAIAANLHVPYRIEIGRTIRDLHSQDKPGKAIIITAPLNDASTILLLSTIELDWTEQARKDGQGSRPGRQHTKILLIDMAASSLDTQHGFYKYLSRMGGSQSDAFARNTGSPAEVVSSNLLVLTLLNDRHRLFLNAAGLMATMQNFRAPLNGNYKDPPPSGHRNASLHKLYPYRNLLPLYDTIVTTTTQSDTSETSPQFDFVVLDIVRDAPVATYKWRP-------LLILESDPGSRGGGSVVEGGGSYISHSIHP-----GYDEWLLVSSVLLWQCGAICWTIAAICVCLLVIMIAGIVAGGIAMRNYFLRKRLSKGPNKIVLSASDFVFPVDSRRVDEGIEAMLCCWLQQLQEFGGPEVDKPDLLKGSIGSLKNLGFVIPGAAAPGSAGAITTTANGKSGSSATGSLARHNPAHLDMRARYNGDLVQLKEVN-INGSAELRTKAMDLLVMAHGLRHENINPLIGWLSD----------PNRTAMVFDYCSRGSLQDVLIMDEIKLDWSFRLSLLTDLVRGMRYLHTSPLRVHGALTSRNCVVDARWVLKITDYGLNSFYESQGLPPRTRSAKELLWTAPELLRNMKLHQHHHQHGRIQLGTQLGDVYSFGIIMQEVVVRGEPYCMLSLSPEEIIVKIKKPPPLIRPSVSKGAAPPEAINIMRQCWAEQPDMRPDFNSVYERFKMLNHGRKVNFVDTMFQMLEKYSNNLEELIRERTEQLDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEFSDVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLPVKIP-DHAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDRLDARG-GYAIEPRGLIDIKGKGMMNTFWLLGKKGFDKPLPAPPPIGESHGLDESLIRNSITLKAQANKSRTSTNPSSSQSSSLAGESVEVKVEITPPTNADLASGTNLPNSYSLDSNSTNTISPNATLCPEFPGKTTPSSTSPQSRKLSELTPENLLNPNSFNRLPSSTGGSSSRLYKKIEEMMDLSSPYNHYKCLSPSESNLTQFYDGKYLYGSVAGGAGGGQAGGGACASIALSGSGCGGGASRFDSKPGSSRLLRRQFSLDRDDQQAKGEQQHHQHSLQANTYSGLVGGCGGGVKSSMLDIPLLHDTTRSPKGTLTRSHKQNSASITQDLEKIEEIPLSPASSQHHSSLDSNLNRSPPSTLEAQSPPLPPMSPPQLSAPTSPAPSRTLNGIYAHNSNSTSSHGAANNNNGTHPGPELTLNAEQLLSRXGTI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. : : * . : .*: : . . . .: .. * .: ::: * : * :: . :: : :. . : :*. . * ** : . :: * * . * .. : .: : : *::* : . : . : : : * * : : . :: :. *.:: :* * * : : : . . : : *. : .*. : .. .:. : . . . : .:*: : : :.:: :* : : .: * : :: :.. . .. : : . . . * * : : :: : : . : .* * : :: .: : . . . . . ::** * **: : : : : : :****: :* : . .:* ::*:****.*:* :::*** *: *** **::*::*** ** *.****:**.*:***:**:* . : :.* : . .:: :*****:**: *.:: ** ***:*:.******: * *:.**.:.***:: :::.**** ** ** . ** : * :* *.*:*.*: ** :: : ** :*:*:*.*::*:*::***:**.***:*******:*: *::**: ** :*** *** ** * .*.** * :**:***********:* ..*::********** **. * ::*************.**:* : ** ::*.*:**:* * *.::*:* * :::*****:** ******.********************* .:***:. .* * : *: :: ** ::**** :*:**:*: **:**:* ** .* . .:.*:*. . . * . . ", "identical_positions": 281, "similar_positions": 288, "identity": "16.36%" }, { "cls_id": "homologset.agr.RGD:620439", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51842-1", "uniprot_id": "GUC2F_RAT", "id": "P51842-1", "name": "Retinal guanylyl cyclase 2", "aln": "----MFLGPWPFSRLLSWFAIS--SRLSGQHGLTSSKFLRYLCLLA---LLPLIWWGQALPYKIGVIGPWTCDPFFSKALPEVAAALAIERISRDMSFDRSYSFEYVILNEDCQTSKALTSFISHQQMASGFVGPANPG--------------YCEAASLLGNSWDKGIFSWACVNHELDNKHS---------------------------YPTFSRTLPSPIRVLVTVMKYFQWAHAGVISSDEDIWVHTANQVSSALRSHG------------------LPVGVVLTSGQD------------------------------------SRSIQKALQQIRQADRIRIIIMCMHSALIGGETQTHFLELAHDLKMTDGTYVFVPY----DVLLYSLPYKHSPYQVLRNNQKLREAYDAVLTITVES-HEKTFYEAFTEAAAGGEIPEKLDSHQVSPLFGTIYNSIYFIAQAMSNALKENGQASAASLTRHSRNMQFYGFN------------------------------------------------------------QLIRTDSNGNGISEYVILDTNGKE----WELRGTYTVDMETELLR----FRGTPIHFPGGRPTSADAKCWFAQGKICQGGIDP-ALAMMVCFALLLALLSINGFAYFIRRRINKIQLIKGPNRILLTLEDVTFIN-----------------------------------PHFGSKRGSRASVSFQIISEVQSGRSPR---LSFSSGSLTPATYENSNIAIYQGDWVWLKKFPPGDFGDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTQDDVKLDWMFKSSLLLDLIKGMKYLHHR-EFIHGRLKSRNCVVDGRFVLKVTDYGFNNILEMLRLSEEEPSEEELLWTAPELLR---------APGGIRLGSFAGDVYSFAIIMQEVMVRGAPFCMMDLSAKEVIDRLKMPPPVYRPVVSPEFAPPECLQLMKQCWAEAAEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPPSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILRTLSEGYEVELRGRTELKGKGTEETFWLVGKKGFTKPLPVPPPVGKDGQVGHGLQPAEIAAFQRRKAERQLVRNKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SDA5-1", "uniprot_id": "GUC2F_MOUSE", "id": "Q5SDA5-1", "name": "Retinal guanylyl cyclase 2", "aln": "----MFLGPWPFSRLLSWFAIS--SRLSGQHGLPSSKFLRCLCLLA---LLPLLRWGQALPYKIGVIGPWTCDPFFSKALPEVAAALAIERISRDKTFDRSYSFEYVILNEDCQTSKALASFISHQQMASGFVGPANPG--------------FCEAASLLGTSWDKGIFSWACVNHELDNKHS---------------------------FPTFSRTLPSPIRVLVTVMKYFQWAHAGVISSDEDIWMHTANRVSSALRSQG------------------LPVGVVLTSGRD------------------------------------SQSIQKALQQIRQADRIRIIIMCMHSALIGGETQTHFLELAHDLKMTDGTYVFVPY----DVLLYSLPYKHSPYQVLRNNPKLREAYDAVLTITVES-HEKTFYEAYAEAAARGEIPEKPDSNQVSPLFGTIYNSIYFIAQAMNNAMKKNGRASAASLVQHSRNMQFYGFN------------------------------------------------------------QLIKTDSNGNGISEYVILDTNGKE----WELRGTYTVDMETELLR----FRGTPIHFPGGRPTSADAKCWFAERKICQGGIDP-ALAMMVCFALLIALLSINGFAYFIRRRINKIQLIKGPNRILLTLEDVTFIN-----------------------------------PHFGSKRGSRASVSFQIISEVQSGRSPR---LSFSSGSLTPATYENSNIAIYEGDWVWLKKFPPGDFGDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTNDDVKLDWMFKSSLLLDLIKGMKYLHHR-EFIHGRLKSRNCVVDGRFVLKVTDYGFNDILEMLRLSEEEPSEEELLWTAPELLR---------APGGIRLGSFAGDVYSFAIIMQEVMVRGAPFCMMDLPAKEIIDRLKMPPPVYRPVVSPEYAPAECLQLMKQCWAEASEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPLSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILQTLSEGYEVELRGRTELKGKGTEETFWLVGKKGFTKPLPVPPPVGKDGQVGHGLQPAEIAAFQRRKAERQLVRNKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51841-1", "uniprot_id": "GUC2F_HUMAN", "id": "P51841-1", "name": "Retinal guanylyl cyclase 2", "aln": "----MFLGLGRFSRLVLWFAAF--RKLLGHHGLASAKFLWCLCLLS---VMSLPQQVWTLPYKIGVVGPWACDSLFSKALPEVAARLAIERINRDPSFDLSYSFEYVILNEDCQTSRALSSFISHHQMASGFIGPTNPG--------------YCEAASLLGNSWDKGIFSWACVNYELDNKIS---------------------------YPTFSRTLPSPIRVLVTVMKYFQWAHAGVISSDEDIWVHTANRVASALRSHG------------------LPVGVVLTTGQD------------------------------------SQSMRKALQRIHQADRIRIIIMCMHSALIGGETQMHLLECAHDLKMTDGTYVFVPY----DALLYSLPYKHTPYRVLRNNPKLREAYDAVLTITVES-QEKTFYQAFTEAAARGEIPEKLEFDQVSPLFGTIYNSIYFIAQAMNNAMKENGQAGAASLVQHSRNMQFHGFN------------------------------------------------------------QLMRTDSNGNGISEYVILDTNLKE----WELHSTYTVDMEMELLR----FGGTPIHFPGGRPPRADAKCWFAEGKICHGGIDP-AFAMMVCLTLLIALLSINGFAYFIRRRINKIQLIKGPNRILLTLEDVTFIN-----------------------------------PHFGSKRGSRASVSFQITSEVQSGRSPR---LSFSSGSLTPATYENSNIAIYEGDWVWLKKFSLGDFGDLKSIKSRASDVFEMMKDLRHENINPLLGFFYDSGMFAIVTEFCSRGSLEDILTNQDVKLDWMFKSSLLLDLIKGMKYLHHR-EFVHGRLKSRNCVVDGRFVLKVTDYGFNDILEMLRLSEEESSMEELLWTAPELLR---------APRGSRLGSFAGDVYSFAIIMQEVMVRGTPFCMMDLPAQEIINRLKKPPPVYRPVVPPEHAPPECLQLMKQCWAEAAEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPPSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILQNLSEGYEVELRGRTELKGKGTEETFWLIGKKGFMKPLPVPPPVDKDGQVGHGLQPVEIAAFQRRKAERQLVRNKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F111-1", "uniprot_id": "E7F111_DANRE", "id": "E7F111-1", "name": "Guanylate cyclase", "aln": "----MPHPSNAFHSFLPARGTSGLRSPSQMPHFSSDPKHIYLCLLWSTIILCLLPATNAATIKVGVVGPWSCDPIFTKAQPGVAARLAVAHINKDPYLSQGITFDYIILDEDCETSKSFARFLGYYTRASGFIGPVNPG--------------YCEAASLLGKSWNKAVFSWSCIEHELDDVRS---------------------------HPTFARTMPVPSLVLLSFMRHFRWAHVGIISSSEDVWVEAAIKLANALRSHG------------------LPVGIVTSARND------------------------------------HTSVRQTLAKVRKVADLRLVILVMHSVLIGGRTQKLLLETAHDMRMTDGSLVFMSY----DTLFYSLPYHHVTQPALRYNSKLLRAYDAVLTITIESPKEQSFYQAFEKAQEDGELPKHLKPQQVSPLFGTIYSSIVFMAHAVQSVRAAGQWMSGGNIAQNARNLLFKGGS------------------------------------------------------------SLQANSSD-FGMLDYVILDTDGFS----WELQPTYRIEMQTDMVR----FLGRHIHFPYAGPPRTDSSCWFTHGIICRGGVNLFHMISMFLLGFLFIFLSIG-CSYCIRRKINKIRLVRGPNKILLTLNDVTFIN-----------------------------------PSLSNKK---LSVDDSKASDTRMSISERS--LVSPMSSQSPATYENSNVAIYEGDWAWMKRLP---YGTFRSITPNTSDVFELMKDLRHENINPFLGFFHDCGVFAIVTEFCSRGSLEDLLVNDDVKLDWMFKSSLILDLIKGMKYLHHR-NVCHGRLKSRNCVVDGRFVLKITDYGYNEVLESQRFPYIEPPAEDLLWTAPEILR---------GSYPGLHGTHSGDVYSFSIIMQEVVMRGPPFCMLENTFDEIVQKVRKPPPMCRPIVSPDHAPMECIQLMKQCWNEQPEKRPTFDEIFDQFKNVNKGKKTNIIDSMLRMLEQYSSNLEELIRERTEELEIEKQKTEKLLTQMLPPSVAEALKLGTTVEPEHFESVSLYFSDIVGFTTISANSEPIEVVDLLNDLYTTFDAVIGNHDVYKVETIGDAYMVASGVPVPNGNRHAAEIANMALDILSAVGTFRMRHMPDVPVRIRIGLHTGPCVAGVVGLTMPRYCLFGDTVTTASRMESTGLPYRIHVHSSTVKILMELKLGYRVELRARTELKGKRIEETYWLTGRDGFTKPLPVPP-VLKSGQMAHGLQMEEIAAYKKRKAEAQLAKKKN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A4D6K026-1", "uniprot_id": "A0A4D6K026_DROME", "id": "A0A4D6K026-1", "name": "Guanylate cyclase", "aln": "MKLTTCQIAKVFPLLTAFFFLNSPSAASLSFGLSPTFASASASSSLSSSSSSSSHFHSEKPLHSDVLVLRAAKPSRAIATSADAATRSVPASAAETTLGSKSIWPTAIQTKSPRNAREAGRHKRQMQKPAIQQQPLQQQQQRINPPQQKRQQQQQQQQQVQHQAQRVGVLIPPSLHVDLTHVQQGFQNFLDFFQLHLFNVTVDFLRDVDLSGFIKLLELPKYTSVIKTLNAGIMVASHVDVDQNSTIYIGTPSQPRQQHRLHSKQEQEPHRHHHEDSKAKQFPAGEEESHSSGETEENHWNDARIFSGHCHQLAEQLALDFNKTVVLWPCPRMKISSNFLPSFEAISLAVQSISTKLNWSQVDIYIGDDNWGLGLAIAANLHVPYRIEIGRTIRDLHSQDKPGKAIIITAPLNDASTILLLSTIELDWTEQARKDGQGSRPGRQHTKILLIDMAASSLDTQHGFYKYLSRMGGSQSDAFARNTGSPAEVVSSNLLVLTLLNDRHRLFLNAAGLMATMQNFRAPLNGNYKDPPPSGHRNASLHKLYPYRNLLPLYDTIVTTTTQSDTSETSPQFDFVVLDIVRDAPVATYKWRPLLILESDPGSRGGGSVVEGGGSYISHSIHPGYDEWLLVSSVLLWQCGAICWTIAAICVCLLVIMIAGIVAGGIAMRNYFLRKRLSKGPNKIVLSASDFVFPVDSRRVDEGIEAMLCCWLQQLQEFGGPEVDKPDLLKGSIGSLKNLGFVIPGAAAPGSAGAITTTANGKSGSSATGSLARHNPAHLDMRARYNGDLVQLKEVNINGSAELRTKAMDLLVMAHGLRHENINPLIGWLSDPNRTAMVFDYCSRGSLQDVLIMDEIKLDWSFRLSLLTDLVRGMRYLHTSPLRVHGALTSRNCVVDARWVLKITDYGLNSFYESQGLPPRTRSAKELLWTAPELLRNMKLHQHHHQHGRIQLGTQLGDVYSFGIIMQEVVVRGEPYCMLSLSPEEIIVKIKKPPPLIRPSVSKGAAPPEAINIMRQCWAEQPDMRPDFNSVYERFKMLNHGRKVNFVDTMFQMLEKYSNNLEELIRERTEQLDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEFSDVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLPVKIP-DHAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDRLDAR-GGYAIEPRGLIDIKGKGMMNTFWLLGKKGFDKPLPAPPPIGESHGLDESLIRNSITLKAQANKSRTSTNPSSSQSSSLAGESVEVKVEITPPTNADLASGTNLPNSYSLDSNSTNTISPNATLCPEFPGKTTPSSTSPQSRKLSELTPENLLNPNSFNRLPSSTGGSSSRLYKKIEEMMDLSSPYNHYKCLSPSESNLTQFYDGKYLYGSVAGGAGGGQAGGGACASIALSGSGCGGGASRFDSKPGSSRLLRRQFSLDRDDQQAKGEQQHHQHSLQANTYSGLVGGCGGGVKSSMLDIPLLHDTTRSPKGTLTRSHKQNSASITQDLEKIEEIPLSPASSQHHSSLDSNLNRSPPSTLEAQSPPLPPMSPPQLSAPTSPAPSRTLNGIYAHNSNSTSSHGAANNNNGTHPGPELTLNAEQLLSRXGTI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :.. . . : .*: :... : * . ** :: : :. : * :. ..:: . .: * : : .: : .:: ..:. :* . . :* *: :. : * :.... ::: :. : . * :. :*.* : . :: : : . : : : : : * ...: : : .: :: .: :.:.* . : .* :. . .: . * * :* *:* : : : : .: . .:. :.* :. :::: . .. : *: . *: ::*:** :: : :: : . * ::. . . * .: : : * : : ::: : .* . :*. : : :* :***:*:*: .*..* :.. : : . . : . .: : * :: ::: : : :: . .: . : *:: : :.*****:**::*:: * . *:* ::*** **:*:* :::**** *: **: **::**:*** ** *.*******.*:***:**** *.. * :. . ::*******:** *: ******.******::** *:**:. . .*:: ::: ***: ** *. ** *.:::*:*** * .: ** *:.::::** .*:*:*.*::*:*::***:**.***:*******:*:**::***:**.:*** **** ** * :*:** *. *::***********:* ..*::********** *** *. ::*************.**:* ** :**.*:**:* * *.::*:* **:::*****:** ******************.********* .:***: .* * ** :* *. ::*** :*:** *:.** ****.** : :. : ..* .*: : : . .. . ", "identical_positions": 303, "similar_positions": 334, "identity": "17.92%" }, { "cls_id": "homologset.agr.RGD:62044", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50406-1", "uniprot_id": "5HT6R_HUMAN", "id": "P50406-1", "name": "5-hydroxytryptamine receptor 6", "aln": "------------------MVPEPG-------------------PTANSTPAWG-----------------AGPPSAP---------------------------GGSG--WVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELG---HARPPVPG------------------------QCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTG--MASQASETLQVPRTPRPGVESAD-------------------SRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP-RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R1C8-1", "uniprot_id": "5HT6R_MOUSE", "id": "Q9R1C8-1", "name": "5-hydroxytryptamine receptor 6", "aln": "------------------MVPEPG-------------------PVNSSTPAWG-----------------PGPPPAP---------------------------GGSG--WVAAALCVVIVLTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELG---KARTSAPG------------------------QCRLLASLPYVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTATAGQALETLQVPRTPRPGMESAD-------------------SRRLTTKHSRKALKASLTLGILLSMFFVTWLPFFVASIAQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFVPCVHCPPEHRASPASPSMWTSHSGA-RPGLSLQQVLPLPLPPNSDSDS--ASGGTSGLQLTAQLLLPGEATRDPPPPTRAPTVVNFFVTDSVEPEIRQHPLGSPMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31388-1", "uniprot_id": "5HT6R_RAT", "id": "P31388-1", "name": "5-hydroxytryptamine receptor 6", "aln": "------------------MVPEPG-------------------PVNSSTPAWG-----------------PGPPPAP---------------------------GGSG--WVAAALCVVIVLTAAANSLLIVLICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELG---KARTPAPG------------------------QCRLLASLPFVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTG--TAGQALETLQVPRTPRPGMESAD-------------------SRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIAQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCVHCPPEHRPALPPPPCGPLTAVPDQASACSRCCLCLCRQTQIQTPLQGAPRACSSQPSFCCLERPPGTPRHPPGPPLWSTSLSQTLWSLRYGRIHSVPP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3ANX4-1", "uniprot_id": "A0A8M3ANX4_DANRE", "id": "A0A8M3ANX4-1", "name": "5-hydroxytryptamine receptor 6", "aln": "MRAEGVKSPTLAGKRWKGLLLQTGHLDLLSHRFRRGGKLFLSLSMNFKKKSWMRVRSEEVRTVLFNSPMMSGSPPIPRVEAASDLWKIHRSFNDSSTISDGWSIGGSGPWLLAVMLSLIILVTACGNILLIALVFAHRSLRCTSNCFLVSLFLSDLMVALVVMPPAMLNVLCGTWVLAPGFCPVWLCFDVMCCSASILNLCVISLDRYLLIISPLRYKQHMTPPRALLLVGGAWGLAALTSFLPIKMDWHSLGRMQELTEDDPGNATHLNSFYPSSYFQLSSSGMPSTQCRLRVTLPFALVATFLTFFLPSTAICFTYCRILLAARRQARQVEALTHP-AYPQHSLGEPSRPPSPGHAIQDGDDYSHQEPPGLRHAPLSVNSERRLAHRQRKRALKASLTLGVLLGLFFSAWLPFFITNMAQAVCECVPPSFFDAITWLGYCNSTMNPIIYPMFMRDFKRALARLLPCCSSSQAPRRPSLPLSLSLRNSGE--PQLPSEPPSLVSDPPQ----------------------LPATATDAVNLLDAEHAGIDLPLLLPNQVDTLDD-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :.* . .. :* .*.*. * **** :*. *.::* :**..* ***.*: :: :** *** ****** *****.**********.* * **** *:* :* .**************:*********:****** :**. *** *: ***.****:****: :.**.** . ** **** .:**:.***: :****** **************:** ** :** . :: . * :* .::..* .***: :: ::*********:**.:** :*****::.:.****:*:.*.:**.:****************:*********.*::** .. : . . . : . . : .: * :. : :. ", "identical_positions": 202, "similar_positions": 102, "identity": "35.31%" }, { "cls_id": "homologset.agr.RGD:620440", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BQZ5-1", "uniprot_id": "CPSF4_MOUSE", "id": "Q8BQZ5-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLK----AACGKGGMCPFRHIS--GEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKF---------------------------------GPLCRHRHTRRVICVNYLVGFCPEGPS-CKFMHPRFELP----MG----TTEQP------PLPQQTQPPTK--------------------------RAPQVIGV--MQSQNSSAGN-----RGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95639-1", "uniprot_id": "CPSF4_HUMAN", "id": "O95639-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLK----AACGKGGMCPFRHIS--GEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNK-ECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPS-CKFMHPRFELP----MG----TTEQP------PLPQQTQPPAKQSNNPPLQRSSSLIQLTSQNSSPNQQRTPQVIGV--MQSQNSSAGN-----RGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5FVR7-1", "uniprot_id": "CPSF4_RAT", "id": "Q5FVR7-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLK----AACGKGGMCPFRHIS--GEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNK-ECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPS-CKFMHPRFELP----MG----TTEQP------PLPQQTQPPTK--------------------------RAPQVIGV--MQSQNSSAGN-----RGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VPT8-1", "uniprot_id": "CPSF4_DROME", "id": "Q9VPT8-1", "name": "Cleavage and polyadenylation specificity factor subunit 4", "aln": "MDILLANVSGLQFKAERDLIEQVGAIPLPFYGMDKSIAAVCNFITRNG--QECDKGSACPFRHIR--GDRTIVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSRFNACHNK-ECPFLHIDPQSKVKDCPWYKRGFCRHGPHCRHQHLRRVLCMDYLAGFCPEGPS-CKHMHPHFELPPLAELGKDQLHKKLPTCHYCGELGHKANSCKQYVGSLEHRNNINAMDHSGGHSGGYSGHSGHIEGADDMQSNHHSQPHGPGFVKVPTPLEEITCYKCGNKGHYANKCPKGHLAFLSNQHSHK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06102-1", "uniprot_id": "YTH1_YEAST", "id": "Q06102-1", "name": "mRNA 3'-end-processing protein YTH1", "aln": "MSLIHPDTAKYPFKFEPFLRQEYSFSLDPDR-------PICEFYNSREGPKSCPRGPLCPKKHVLPIFQNKIVCRHWLRGLCKKNDQCEYLHEYNLRKMPECVFFSKNGYCTQSPDCQYLHIDPASKIPKCENYEMGFCPLGSSCPRRHIKKVFCQRYMTGFCPLGKDECDMEHPQFIIP-----------------------------------------------------------------------DEGSKLR------IKRDDEINTRKMDEEKERRLNAIINGEV----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : ... *. * : :: . * .:*:* * :* ** :*: :..:**:*********.****:****:: ***** *:*: *. * ::* ::*:* *:.**** * . *. **:* :* :. * . * * :* : * :*.: ", "identical_positions": 59, "similar_positions": 47, "identity": "19.54%" }, { "cls_id": "homologset.agr.RGD:620441", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14097-1", "uniprot_id": "CCL4_MOUSE", "id": "P14097-1", "name": "C-C motif chemokine 4", "aln": "MKLCVSALSLLLLVAAFCAPGFSAPMGSDPPTSCCFSYTSRQLHRSFVMDYYETSSLCSKPAVVFLTKRGRQICANPSEPWVTEYMSDLELN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50230-1", "uniprot_id": "CCL4_RAT", "id": "P50230-1", "name": "C-C motif chemokine 4", "aln": "MKLCVSAFSLLLLVAAFCDSVLSAPIGSDPPTSCCFSYTSRKIHRNFVMDYYETSSLCSQPAVVFLTKKGRQICADPSEPWVNEYVNDLELN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13236-1", "uniprot_id": "CCL4_HUMAN", "id": "P13236-1", "name": "C-C motif chemokine 4", "aln": "MKLCVTVLSLLMLVAAFCSPALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQPAVVFQTKRSKQVCADPSESWVQEYVYDLELN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NHW4-1", "uniprot_id": "CC4L_HUMAN", "id": "Q8NHW4-1", "name": "C-C motif chemokine 4-like", "aln": "MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQPAVVFQTKRGKQVCADPSESWVQEYVYDLELN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:.:***:****** :***:******:******:*:: *.**:**********:***** **:.:*:**:***.** **: *****", "identical_positions": 65, "similar_positions": 20, "identity": "70.65%" }, { "cls_id": "homologset.agr.RGD:620442", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62785-1", "uniprot_id": "HAP28_RAT", "id": "Q62785-1", "name": "28 kDa heat- and acid-stable phosphoprotein", "aln": "MPKGGRKGGHKGRVRQYTSPEEIDAQLQAEKQKAN----EEDEQEEGGDGASGDP-------------KKEKKS-------------LDS--DESEDEDDDYQQKRKGVEGLIDIENPNRVAQT-TKKVTQLDLDGPKE---------LSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKRMQSLSLNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHX2-1", "uniprot_id": "HAP28_MOUSE", "id": "Q3UHX2-1", "name": "28 kDa heat- and acid-stable phosphoprotein", "aln": "MPKGGRKGGHKGRVRQYTSPEEIDAQLQAEKQKAN----EEDEQEEGGDGASGDP-------------KKEKKS-------------LDS--DESEDEDDDYQQKRKGVEGLIDIENPNRVAQT-TKKVTQLDLDGPKE---------LSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKRMQSLSLNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13442-1", "uniprot_id": "HAP28_HUMAN", "id": "Q13442-1", "name": "28 kDa heat- and acid-stable phosphoprotein", "aln": "MPKGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAR----EEEEQKEGGDGAAGDP-------------KKEKKS-------------LDS--DESEDEEDDYQQKRKGVEGLIDIENPNRVAQT-TKKVTQLDLDGPKE---------LSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKRMQSLSLNK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4J4-1", "uniprot_id": "Q9W4J4_DROME", "id": "Q9W4J4-1", "name": "Casein kinase substrate phosphoprotein PP28 domain-containing protein", "aln": "MPRG-KFVNHKGRSRHFTSPEELQQESEEDSDQTSGSGSDSDDKDAAGGKASSSASKAKAPATRKAPVNRNQKSRSAAGAGAASSSESESGEDSDDDSEAEARDAKKGVASLIEIENPNRVTKKATQKLSAIKLDDGPAGAGGNPKPELSRREREQIEKQRARQRYEKLHAAGKTTEAKADLARLALIRQQREEAAAKREAEKKAADVGTKK-------PGAK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLC4-1", "uniprot_id": "Q9VLC4_DROME", "id": "Q9VLC4-1", "name": "Casein kinase substrate phosphoprotein PP28 domain-containing protein", "aln": "MPRG-KFLSYKGRTRQFTSPEELRQESEDDYDQVSGSGSDSDEKVATRGGANSSSSIAKDRTLKKA--TRNQKS---------SSDEVDS---SSEDCETESRVARKGVASLIEIDNPNRVSKKGPQKISAIMLDQTKAG--------LSRRDQD----QSARKRYEKLHVAGKTTEARADLARLALIRKQREETAARREAEKKAANVVTKK-------PFAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* : .:*** *::*****: : : : ::. :.::: . * ... .:::** :* ..:* : : : :*** .**:*:*****::. .:*:: : ** ****::: * *::** *:* **** :*:*******:**:****:* ::* *:** : * . . *", "identical_positions": 66, "similar_positions": 62, "identity": "29.6%" }, { "cls_id": "homologset.agr.RGD:620443", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63355-1", "uniprot_id": "MYO1C_RAT", "id": "Q63355-1", "name": "Unconventional myosin-Ic", "aln": "-------------------MRYRASALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYTRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHVFYQLLEGGEEEALRRLGLER-NPQSYLYLVKGQCAKVSSINDKSDWKVVRKALSVIDFTEDEVEDLLSIVASVLHLGNIHFAADEDSNAQVTTENQLKYLTRLLGVEGTTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVRKINRSLASKDAESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTIKHHPHFLTHKLADQKTRKSLDRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSTNPIMAQCFDKSELSDKKRPETVATQFKMSLLQLVEILRSKEPAYIRCIKPNDAKQPGRFDEVLIRHQVKYLGLMENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPVWTG--RPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDSLEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFILRHAPRCPENAFFLDHVRTSFLLNLRRQLPRNVLDTSWPTPPPALREASELLRELCMKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTEEISPR---VLQALGSE-PIQYAVPVVKYDRKGYKPRSRQLLLTPSAVVIVEDAKVKQRIDY-ANLTGISVSSLSDSLFVLHVQREDSKQKGDVVLQSDHVIETLTKTALSADRVNNININ-QGSITFAGGPGRDGIIDFTSGSELLITKAKNGHLAVVAPRLNSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTI7-1", "uniprot_id": "MYO1C_MOUSE", "id": "Q9WTI7-1", "name": "Unconventional myosin-Ic", "aln": "MALQVELIPTGEIIRVVHPHRPCKLALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHVFYQLLEGGEEETLRRLGLER-NPQSYLYLVKGQCAKVSSINDKSDWKVMRKALSVIDFTEDEVEDLLSIVASVLHLGNIHFAADEDSNAQVTTENQLKYLTRLLGVEGTTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVRKINRSLASKDAESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKPHPHFLTHKLADQKTRKSLDRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSMNPIMAQCFDKSELSDKKRPETVATQFKMSLLQLVEILRSKEPAYIRCIKPNDAKQPGRFDEVLIRHQVKYLGLMENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPMWAG--RPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDSLEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFILRHSPRCPENAFFLDHVRASFLLNLRRQLPRNVLDTSWPTPPPALREASELLRELCMKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTEEISPR---VLQSLGSE-PIQYAVPVVKYDRKGYKPRPRQLLLTPSAVVIVEDAKVKQRIDY-ANLTGISVSSLSDSLFVLHVQREDNKQKGDVVLQSDHVIETLTKTALSADRVNNININ-QGSITFAGGPGRDGIIDFTSGSELLITKAKNGHLAVVAPRLNSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00159-1", "uniprot_id": "MYO1C_HUMAN", "id": "O00159-1", "name": "Unconventional myosin-Ic", "aln": "MALQVELVPTGEIIRVVHPHRPCKLALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLER-NPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCFDRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAG--RPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPR---VLQALGSE-PIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQRIDY-ANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQSDHVIETLTKTALSANRVNSININ-QGSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAVVAPRLNSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PF48-1", "uniprot_id": "MYO1C_DANRE", "id": "A5PF48-1", "name": "Unconventional myosin-Ic", "aln": "-----------------------------------MESALSARDRVGVQDFLLLENHNSEAAFIENLRRRYREGLIYTYIGSVLVSVNPYKELEIYSKQNMERHRGVNFYEISPHIFALADNSYRALRTERRDQCILISGESGAGKTEASKKILQYYTHICPTRNNTHTIRERLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDYKGAPIGGHILNYLLEKSRVAHQNHGERNFHIFYQLLEGGEDLLLKRLGLDKTNPQHYHYLIKGNCPRVSSISDKNGWKVVRNALTIIGFEDEEIQALMEIVASVLHLGNTQFGEDEEGETHITTEAQLQFLSQLLGVDGSVLKAALTHKKIVAKGEEMISPLSLEQALSARDSFAKAIYGRAFTWLVQKLNRSLAFKDEIYYSSKCSSVIGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEG--WERVEYFNNKIICDLVEEKHKGIIAILDEECLRRGDASDITFLEKLEDTLGGHAHFITHKMANGKIRKAIGREEFRLVHYAGEVNYNVNGFLDKNNDLLYRHLKEVLCQSTNHIVSQCFHADELMDQRRPETAATQFKLSLAKLMDILMSKEPSYVRCIKPNDGKQPGRFDEVLVRHQVKYLGLMENLRVRRAGFAYRRSYEAFLERYKSLCPDTWPNWHG--NLPEGVATLVKHLNYKPEEFKLGRSKIFIRFPRTLFITEDALEAQKQTIAVTLQKSWRGYRERANYHRIRHAVIVIQSWWRGVKGRRKAKHRRQAADTIRNFIKGFILRNEPRCPDNEYFLDHVRFSFLMKVKRNLPKSVLDKSWPKPPPSLTEASEHIHRICIRNLVNDYCRRIQPEWRKQLEQKVVASGIFKGQKDGYSRSVPKLFVATRLEAEEINLK---VLQTLGSDNKVKYGIAVTKYDRHGFRPRVRQLLLTTSSAVLVQEAKIKQRIDY-GALLGISVSSLSDGFFVLHIPTADSKQKGDLVLQCDHVIEAVTKLAIMADKIHNVNIS-QDSIRFAIARGKEGVIDFTSGSDLRVVKSKNGHLSVTTPRIS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q23979-1", "uniprot_id": "MY61F_DROME", "id": "Q23979-1", "name": "Unconventional myosin IC", "aln": "--------------------------MASFNSQLKMETGLHERDRAGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRLER-ALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGFT-EVEGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDARGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETRAS---RNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKHKGIISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEKELRSLKRPETAITQFRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQRRKYLKLRAQVIIMQSYCRRKLAQQAAKKRREAADKIRAFIKGFITRNDAPNGFNEEFIANAKRMWLLRLAKELPTKVLDKSWPHAPGHCEEASGILHRLHRLHLARIYRLKLTPQQKRQFELKVLAEKVFKGKKNNYASSVSTWFQEDRIPKEHIQRVNDFVASTFGSE-QLKYQSFCTKFDRHGYKSRDRFILLSNKAIYVLDGKTYKQKHRLPLDKIDFTLTNHNDDLMVIRIPLDLKKDKGDLILIIPRIIEFSTYIIDTVGTASIVSIVDRNSLEHNVVKGKGGVIDIQTGAEPGVVRDK-GHLVIIGTQ----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:.* ***.*****:****. ** *** **::*::*.******* **:*****::* **: :::: :*. ***:.**:**::*. :*:* *.*.*.::******:*****:*::**: : . ::::**:************* *************:***:****:**:**.********. * ******:***** *.:: *:.* *:: : * ** .* *: *.* ..:* :::**::*.* .:* . :: ****:***** * : :.::::.:. : ::**.*:.: *. ****:.* *:*: : ***. * * ***::***:*.* *:*** ::* ** *: ..*:*:*******:**:*********:******************:**. ** * *:**:**:**:*:***.****:******** *:.:* ****** :.: * *:: *: * : :* : * ****:******.*.*.**********:*.***.:..: * *: :** .** . :****. ***: ** :*::** .***:*:******* : .. *:: *: ********:**************.** **:*****. .*** : * ** **:.*.:. *::::*.:*:***:*:*** ***: : ::: :*. :* *:* * :: ::: .* :**: * .:: * :*: **:.** :*:**: *: . * *: :.: :*:.: ::** .***.*** .* *** ::.: ::. * : *: ::*:: *.:*. :***:*:.*. **. * *: :.*. * .::**: ::* .*:**:*::.* * :**: .: ::: . **: .::::. .*.::*::: .*:***::* ::** * .. :.* :.*: . *: * **: .*:: :.: * *** : .: ", "identical_positions": 461, "similar_positions": 315, "identity": "43.0%" }, { "cls_id": "homologset.agr.RGD:620444", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62661-1", "uniprot_id": "HBP1_RAT", "id": "Q62661-1", "name": "HMG box-containing protein 1", "aln": "-------------MVWEVKTNQRPHAVQRLLLVMDERATGVSDSLELLQCNENVPSSPGYNSCDEHMELDDLPELQAVQSDPTQSAIYQLSSDVSHQEYPRPSWSQNTSDIPENTHREDEVDWLTELANIATSPQSPLMQCSFYNRSSPVHIIATSKSLHSYARPPPVSS-AKSGPAFPHDHWKEETPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTVWHCFLKGTRLCFHKESKKEWQDVEDFAR-AASCD-EEEIQMGTHKGYGSDGLKLLSHEESVSFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEIHIGDVCLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGG-PGTGQEFAGSEFSKSCGSPGSSQLSSSSLYTKAVKSHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R316-1", "uniprot_id": "HBP1_MOUSE", "id": "Q8R316-1", "name": "HMG box-containing protein 1", "aln": "-------------MVWEVKTNQMPNAVQKLLLVMDKRAPGMSDSLELLQCNENLPSSPGYNSCDEHMELDDLPELQAVQSDPTQSAIYQLSSDVSHQEYPRSSWSQNTSDIPENTHREDEVDWLTELANIATSPQSPLMQCSFYNRSSPVHIIATSKSLHSYARPPPVSSSSKSGPAFPHDHWKEETPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTIWHCFLKGTRLCFHKESNKEWQDVEDFAR-AASCDNEEEIQMGTHKGYGSDGLKLLSHEESVSFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEIHIGDVCLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGGGPGTGQEFSGSEFSKSCGSPGSSQLSSSSLYAKAVKSHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60381-1", "uniprot_id": "HBP1_HUMAN", "id": "O60381-1", "name": "HMG box-containing protein 1", "aln": "-------------MVWEVKTNQMPNAVQKLLLVMDKRASGMNDSLELLQCNENLPSSPGYNSCDEHMELDDLPELQAVQSDPTQSGMYQLSSDVSHQEYPRSSWNQNTSDIPETTYRENEVDWLTELANIATSPQSPLMQCSFYNRSSPVHIIATSKSLHSYARPPPVSSSSKSEPAFPHHHWKEETPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTVWHCFLKGTRLCFHKGSNKEWQDVEDFAR-AEGCDNEEDLQMGIHKGYGSDGLKLLSHEESVSFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEVHIGDVCLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGG--PGGQDFARSGFSKNCGSPGSSQLSSNSLYAKAVKNHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N6K3-1", "uniprot_id": "A0A8M1N6K3_DANRE", "id": "A0A8M1N6K3-1", "name": "HMG box-containing protein 1", "aln": "MATGLPAQLTCHNMVWEVKSQSVPQRVQ----EVQAQSSGMDEAFDLLKCNEHLSSSPGCPAKESQMEYDDLPELQEVQDDQLAPGVFQVAPGVSHHE--------------EGPGSDSHTNWLTELANIATSPQSPLLQNAPHTRSSPVHIFSSSSSLHSYARPPLSSS---SAPSPARSHMRER---RRTRASSESESGVFCMSSLSDDDDLGWSHSWPSTAWHCFLKGTRLRFHKGPNVEWQEADDVLESDEDSDDERGAQSNPMKSYGSDGLKLVIFEESVSFGQSVLKLTFDPGSPEAGLLTAECSLDHPFFVKNKGWSSFYPSLTVVRHGIPCYDMQVGDLCLPPGHRDAINCDDSVVFDTFKSYDFTPLDSSAVYVLSSMGRQRRASQSSGG-----------AVSPDCDKLEALGFTHHSSSSKSQRSHASGSSGAT-PTKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDKWKKMKNEERRMYTMEAKALAEEQKRLNPDCWKRKRTNSGPQQN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******::. *: ** :: ::.*:.::::**:***::.**** : :.:** ******* **.* ..::*::..***:* * . :...:****************:* : :.*******:::*.********* ** * *: .: * :*. *: **.******:**************.:***** ********** *** .: ***:.:*. . ..* *. * . *.********: .*******:**********: * ****.**.*****:****************:***** ::::**:****** **** *** ************:***********.****** *.** .* .*.. : :: * :*: :.*:**: .** *.**************************************:*************:*************************.**:", "identical_positions": 319, "similar_positions": 104, "identity": "60.19%" }, { "cls_id": "homologset.agr.RGD:620445", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62314-1", "uniprot_id": "TGON2_MOUSE", "id": "Q62314-1", "name": "Trans-Golgi network integral membrane protein 2", "aln": "MRFQVALLLLSVAVARALP-------------------------PVYKRDADSGDSQNPPNQPSKQSSTPLPP---ESSNQVKTTRPTDGQGQKSDKKDQDKTTLAAVSSKAESGPPTAATDHSLGDSRRQPEK-------TDAELKETARPLSPVNPKLEK-------SDQSSTEDSGKPTGGNSGKPTGGD------------------------------SGKPTGGDSDKPTEAGSNKATEDDS------GKSTKVDLDKPTSKIFPDTETSKTDKVQPTEKGQKATLTSKTESGETLAGDSDFSLKPEKGDKSSEPTEDVETKEIEEGDTEPEEGSPLEEENEKVSGPSSSENQEGTLTDSMKNEKDDLYKDSSGNTSAESSHFFAYLVTAAVLVAVLYIAYHNKRKIIAFALEGKRSKVTRRPKASDYQRLNLKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62313-1", "uniprot_id": "TGON1_MOUSE", "id": "Q62313-1", "name": "Trans-Golgi network integral membrane protein 1", "aln": "MRFQVALLLLSVAVARALP-------------------------SVYKRDADSGDSQNPPNQPSKQSSTPLP-----SSNQVKTTRPTDGQGQKSDKKDQDKTTLAAVSSKAESGPRTAATDHSLGDSRRQPEK-------TDAELNETARPLSPVNPKLEK-------SDQSSTEDSGKPTGGNSGKPTGGD------------------------------SGK--------PTEAGSNKATEDDS------GKSTKVDLDKPTSKISPDTETSKTDKVQPTEKGQKPTLTSKTESGETLAGDSDFSLKPEKGDKSSEPTEDVETKEIEEGDTEPEEGSPLEEENEKVPGPSSSENQEGTLTDSMKNEKDDLYKDSSGNTSAESSHFFAYLVTAAVLVAVLYIAYHNKRKIIAFALEGKRSKVTRRPKASDYQRLNLKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19814-1", "uniprot_id": "TGON3_RAT", "id": "P19814-1", "name": "Trans-Golgi network integral membrane protein TGN38", "aln": "MQFLVALLLLSVAVARALP-------------------------SASKPNNTSSEN-NPPIQP----STPLPPGV-DISQQVKTNRPTD-QRLESDKEGQDK-TVARTSASVSSG-VESATNLNLDDSKKHPET-------ADAKLKETLQQLLPVDPKQEK-------SGQKFTKDSGSPTGGDSDNTTGGD------------------------------SNKTTGVDSDKTSGGDSNKPTGSDN------DKPTGGDSNKPTSKVPSNTETPKIDKVQLTEKGQKPTLISKTESGEKLAGDSDFSLKPEKGDKSSEPTEDVETKEIEEGDTEPEEGSPLEEENEKVLGPSSSENQEGTLTDSMKDEKDDHYKDNSGNTSAESSHFFAYLVTAAVLVAVLYIAYHNKRKIIAFALEGKRSKVTRRPKASDYQRLNLKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43493-2", "uniprot_id": "TGON2_HUMAN", "id": "O43493-2", "name": "Trans-Golgi network integral membrane protein 2", "aln": "MRFVVALVLLNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGE----ETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESSHFFAYLVTAAILVAVLYIAHHNKRKIIAFVLEGKRSKVTRRPKASDYQRLDQKS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* ***:**.**.* *:* . : * .. * * *.. . . *: :. * .*:*.. : * ::. * : . . .... :. . ::*: * .:.* :* * . *:* . :*.:. ....*. *. .: ..::: * .*. :.: * .** *: :.* .* *. * ::**: .. ****** ::*: *:: **********.** *:.** ****** :**:**: *.:****:****:** .**** * :.*** ***************:********:*********.********************: * ", "identical_positions": 149, "similar_positions": 99, "identity": "33.79%" }, { "cls_id": "homologset.agr.RGD:620446", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M824-1", "uniprot_id": "SHC1_RAT", "id": "Q5M824-1", "name": "SHC-transforming protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGAMRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEE---ELPDHQYYNDFPGKEPPLGGVVDMRLREG----AARPTLPSTQMPSHLGATLPIGQHVTGDHEVRKQMLPPPPCPGRE--LFDDPSYVNIQNLDKARQAGGGAGPPNPSVNGSAPRDLFDMKPFEDALRVPPAPQSMSMAEQLQGESWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVDRKV-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98083-1", "uniprot_id": "SHC1_MOUSE", "id": "P98083-1", "name": "SHC-transforming protein 1", "aln": "MDLLPPKPKYNPLRNESLSSLEEGASGS-----------TPPEELPSPSASSLGPILPP---LPGDDSPTTLCSFFPRMSNLKLANPAGGRLGPKGEPGKAAEDG-EGSAGAALRDSG--------LLPLL------------QDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEE---EPPDHQYYNDFPGKEPPLGGVVDMRLREG----AARPTLPSAQMSSHLGATLPIGQHAAGDHEVRKQMLPPPPCPGRE--LFDDPSYVNIQNLDKARQAGGGAGPPNPSLNGSAPRDLFDMKPFEDALRVPPPPQSMSMAEQLQGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVDRKV-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29353-1", "uniprot_id": "SHC1_HUMAN", "id": "P29353-1", "name": "SHC-transforming protein 1", "aln": "MDLLPPKPKYNPLRNESLSSLEEGASGS-----------TPPEELPSPSASSLGPILPP---LPGDDSPTTLCSFFPRMSNLRLANPAGGRPGSKGEPGRAADDG-EGIVGAAMPDSG--------PLPLL------------QDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEE---EPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRE--LFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1Z9-1", "uniprot_id": "A0A8M6Z1Z9_DANRE", "id": "A0A8M6Z1Z9-1", "name": "SHC-transforming protein 1", "aln": "MELVP-KTKYTPFRSDSFSSTDETASNPSLPSSAPLTPLTPPGIPPSLSSSSLTPILPPSSPRQAENSPTTLCSFFPRMGALRLGVSSTLLPGLKASSRPANVPGSQGGLGESSEDTGTVNSSPPRLLPLLSLTAPSPPPRPPQDMNRL-GGASRRARVEGGQLGGDEWTRHGSFVNKPTRGWLHSDIVVSTSGVSYTVRYMGCVEVLQSMRALDFNTRTQVTREAISVVCEAVPGAKGAQRRRKPSSRCLSSILGKSNLQFAGMTITLTVSTSSLNLMAIDCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECSEGLAQEVISTIGQAFELRFKQYLKNPPKVVTPHDRMAPFDGSAWEEEEEDLAPPPEVPYYNNFPGKQPPPGGLVDMRTRPG----------------HSTGPTLPYGQPSQND--IHKQPLPPLPVGVKDGGLFDDPSYVNVD---KPR------LPASAAANGNAHRDAFDMKPFDAALVVSG-AVALPLAEQLQNEPWFHGPLSRRQAERLLTKDGDFLVRESGTTPGQYVLTGQQGGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNRLPIISAGSEVCLQQPVDRKA-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3C8-1", "uniprot_id": "Q9V3C8_DROME", "id": "Q9V3C8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MPKNGDAGNRSGS--GTTSDGCIYPDDVIMGVGVAFNVRYTGCVEVKTSMKSLDFETRTQLARECINRVCEAA-GLKSAGKRRLTN-----FISDRPSMQHAGTNIIINVSSRALSLSNVETGEVIANHNMPRISFASGGDNDTLDFLAYIAKNEDEWRACYVLECAGGQSEDLIVTIGKAFALRFNALSR----LNDPSADCN-INQSCKENVKE---------YYNDLPNKLPP---------------------------------EVPEPQQQQVQQPLHPHAPRVAQLNLKK--PRDRLSSNLIDLN---------SPPPDQTTNKLGHFDPLQATTAANSVLPSVRDVFDGPQCPLTAEVWFHAGISRPISERLLQQDGDFLVRESQGKRGQYVLTGLEGKTPKHLLLIDPEGVVRTKDRIFDSISHLINYHWAHALPIISEDSELVLRNPVRRPQQDQAASPITSASS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*: .* ** ...: * ::.: : **:: *** ***** **::***:****::**.*. ****. * *.* :** . * .:..::.** * :.**: :*.* : ::****:* ******** ** :::**:**: : ***::***. * ::::* ***:** ***: : : * :: *. :: :* ***::*.* ** :* * : :: : :. * * :: *.. : * . * :: .. :: . * * ***. :** :* ** :******** . ******* :. ******:**********: *:*:****.** : ***** .**: *::** * ", "identical_positions": 156, "similar_positions": 104, "identity": "24.53%" }, { "cls_id": "homologset.agr.RGD:620447", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61023-1", "uniprot_id": "CHP1_RAT", "id": "P61023-1", "name": "Calcineurin B homologous protein 1", "aln": "MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFSEG-EDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61022-1", "uniprot_id": "CHP1_MOUSE", "id": "P61022-1", "name": "Calcineurin B homologous protein 1", "aln": "MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFSEG-EDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFLH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99653-1", "uniprot_id": "CHP1_HUMAN", "id": "Q99653-1", "name": "Calcineurin B homologous protein 1", "aln": "MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEG-EDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDVEQKMSIRFLH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNF9-1", "uniprot_id": "Q9VNF9_DROME", "id": "Q9VNF9-1", "name": "", "aln": "MGNKSSLFLRNEEIAQIQEETGFTPNQIERLYSRFTSLDRNDCGTLSREDLMRIPELAINPLCERIVHSFFAESNDDRVNFRQFMNVLAHFRPLRDNKQSK-------LNSREEKLKFAFKMYDLDDDGVISRDELLSILHMMVGANISQDQLVSIAERTILEADLCCQGKISFEDFCKALDRTDVDQKMSIRFLN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.::* :**:**: :*::****: .** **********:.: *******: ********** :**:::**.*. :*:**** **..******:.**::** ****.:**:***::****.* *******.:*:****.***::** ***:*** *** :. *** :* *.*::.**:********:", "identical_positions": 119, "similar_positions": 51, "identity": "60.71%" }, { "cls_id": "homologset.agr.RGD:620448", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIX3-1", "uniprot_id": "FHIT_RAT", "id": "Q9JIX3-1", "name": "Bis(5'-adenosyl)-triphosphatase", "aln": "--MSFKFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLMCPLR-PVERFRDLRPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHILPRKSGDFRRNDNIYDELQKHDREE-------------------------------------------EDSPAFWRSEEEMAAEAEVLRAYFQA------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89106-1", "uniprot_id": "FHIT_MOUSE", "id": "O89106-1", "name": "Bis(5'-adenosyl)-triphosphatase", "aln": "--MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLR-PVERFRDLHPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHVLPRKAGDFPRNDNIYDELQKHDREE-------------------------------------------EDSPAFWRSEKEMAAEAEALRVYFQA------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49789-1", "uniprot_id": "FHIT_HUMAN", "id": "P49789-1", "name": "Bis(5'-adenosyl)-triphosphatase", "aln": "--MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLR-PVERFHDLRPDEVADLFQTTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHDKE---------------------------------------------DFPASWRSEEEMAAEAAALRVYFQ-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49775-1", "uniprot_id": "HNT2_YEAST", "id": "P49775-1", "name": "Bis(5'-adenosyl)-triphosphatase", "aln": "MNKPIYFSKFLVT-EQVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQYKADSINVAIQDGPEAGQSVPHLHTHIIPRYKINN-VGDLIYDKLDHWDGNGTLTDWQGRRDEYLGVGGRQARKNNSTSATVDGDELSQGPNVLKPDSQRKVRALTEMKKEAEDLQARLEEFVSSDPGLTQWL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: *.:.*:. . ** *:: ::**** **:******: *** .* .: ** * * *:. * : .:: :::. *:..::********:* *:*.*::** : .* **::*:: * : * *: ** ** *:. :: ", "identical_positions": 54, "similar_positions": 49, "identity": "25.96%" }, { "cls_id": "homologset.agr.RGD:620449", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920M9-1", "uniprot_id": "SIAH1_RAT", "id": "Q920M9-1", "name": "E3 ubiquitin-protein ligase SIAH1", "aln": "MS------RQTATALPTG-----------TSKCPPSQRVPALTGTTASNN---------------DLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61092-1", "uniprot_id": "SIA1A_MOUSE", "id": "P61092-1", "name": "E3 ubiquitin-protein ligase SIAH1A", "aln": "MS------RQTATALPTG-----------TSKCPPSQRVPALTGTTASNN---------------DLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUQ4-1", "uniprot_id": "SIAH1_HUMAN", "id": "Q8IUQ4-1", "name": "E3 ubiquitin-protein ligase SIAH1", "aln": "MS------RQTATALPTG-----------TSKCPPSQRVPALTGTTASNN---------------DLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVG6-1", "uniprot_id": "SIAH1_DANRE", "id": "Q7ZVG6-1", "name": "E3 ubiquitin-protein ligase Siah1", "aln": "MS------RQTATALPTG-----------TSKCPPSQRVPTLSGTTASNS---------------DLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEVTLPHTDKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLLHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06985-1", "uniprot_id": "SIA1B_MOUSE", "id": "Q06985-1", "name": "E3 ubiquitin-protein ligase SIAH1B", "aln": "MS------RQAATALSTG-----------TSKCPPSQRVPALTDTTASNN---------------DLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAVEKVANSVLFPCKYSASGCEITLPHTKKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21461-1", "uniprot_id": "SINA_DROME", "id": "P21461-1", "name": "E3 ubiquitin-protein ligase sina", "aln": "MSNKINPKRREPTAAAAGAGATGVATNTSTSTGSSSAGNTSSANTSSSSSSSLSSAGGGDAGMSADLTSLFECPVCFDYVLPPILQCSSGHLVCVSCRSKLTCCPTCRGPLANIRNLAMEKVASNVKFPCKHSGYGCTASLVYTEKTEHEETCECRPYLCPCPGASCKWQGPLDLVMQHLMMSHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYDGHQQFFAIVQLIGSRKEAENFVYRLELNGNRRRLTWEAMPRSIHEGVASAIHNSDCLVFDTSIAQLFADNGNLGINVTISLV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *: .** .:* **. ..* .: :.*::*.. **:*******************.****** .**.************..*****:****..* ****::. ** :* :*.*::*** ** *** ************.** ** **: .***********************************.**************************:**:****.*******:******** *******:*:** ****************:***********: ", "identical_positions": 216, "similar_positions": 44, "identity": "68.79%" }, { "cls_id": "homologset.agr.RGD:620450", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R095-1", "uniprot_id": "SPEF2_RAT", "id": "Q9R095-1", "name": "Sperm flagella and cilia-associated protein 2", "aln": "MSEILCQWLNQELKVSRTVSPKSFAKTFSNGYLIGEVLFKFELQSDFSEFSESRVSTAKLNNFSRLQPTLHLLGVQFDQNVAQSIITEKPGAATKLLYQLYIALQKKKKTGLTGLEIQTMQPQTNQRLQALKSEAFRERLKNLIPRQTDFNLMRVTCRFQEKCKQMKEDLARMHFEKFEKIQKLEEEQRHFNIEKQRLNRRRQNEIMAKIQAAIIQIPKPEPNRTLKAIEAQKLMKKKKEAEDVANEIKKFEALIKKDLQTRESISKTSLDTIDQTAAELLNTYSDDDYIKKIQKRLEEDAFAREQREKRRRRLLMDQLIAHEAQEEAYREEQLIHRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQFEERRLKDFQDALDREAALTKQAKIDFAEQTLRAKEIHEKIAMERAQQRYEKHYGICAEILDQILDLCTKVADYRLLTNNLIPHKMMRDWKELFFSGNPIYEQTSHTHGQTESTEDHHVELNKRNLLDSKDYEDYKNMTGEWALPEDMANSSPPSNNNILGHVLLRLIENSYPSEKEVADTELPSFAVKGCLLGKTLSGKTTILKALQNDIPIQVLSIDTLVQEAIQAFNDGEKSSKAPSMHEDVKGDPE-VDQKEMIIPQD-KNELTDTQVPGEAAPQKE--------GTKSSDFEQFRPSNSFLSLSMRAQLGAKSELMLRRGKSVPDVLLVNILVNAIKKIPVNQSWVLDGFPMTVNQAKLLEEALTGYKRKSLQLKKKKAQMPTLALSPTTSKEVPFLPSAFDFAILLDISDNSSLARIN-------------DIIAKEISHEISHENVSGP-TITSS-EEKSEDRNL-RDHIQHRIVGFLDNWPLLEEWFTEPRNILKKVNAEIDEAFLCQKIKEIFATEVSNKKIKVEKKLEEKETEKKSAVSPTEPPTPTPPLAS--EAEKEKEVHQAKPS-----GKGKTQS-------------------------VSPKGKAQGGKISVKKSPIDSTEVSPTLIAMPTTKPGSEEWVYVTEPIPEELPSFLVPYWELIEKTYISHIKTVLRQLRESQHTVLSYLYETRTSFQEFLRRPDHKQDFVSQWQADFNSVPEDLWEDEETKAELHQRVNDLRDRLWDICEARKEEAEQERLDIINESWLQDYIGITMNHFFSLMQAEVNRFQDTKRLLQDYYRAMESRIPLEDNKKFTRIPLVQLDGK---EISEHQLRIPLVPRISSSPENVS-----MRPKVKALLKGRFDPPLESLEANFEGDEKIVLDTWQQASLAISQMVAAEVHQRLAEEEKEQPQLDPKEKSPQSGTNKKAKKEKEQAKKEKEQAKKEKEQAKKEKEPPKKKMAEKKGKGKSSPVVEVSPVTITPEEMAEMERKNELKLKIKEEHLAALQTEEQATQFRLELIKSKALSILEDLVTKVIEVYRFMEKWLGKRYLNEMASIQKLTEVARYHIETATKIQNEIYLSQEDFYINGDIKVFPDPPPPTRPPPVEKEENGTLTIEQLDNLRDQFLDMAPKGIIGNKAFTDILLDLVTLNLGTNNLSSSWMHLTQLDLQEITSLLTVNTEFVDWRKFLMVAAMPWPIPLEEELLETLQRFKATDEAQTGTITFEQYKQAGLWFSGDEDIKIPENPLEPLPFNRQEHLIEFFFRLFADSEKDPPQLDYTQMLLYFACHPDTLEGVYRALSVAVGTHIFRQVETPMLTAEKTSISSVSPNEEFPEAEENSTREELKEEKD--ERDQKEEEIPENANTEKISMETLLKVFGGGNE-VLDANRFASYLKTENIYSENLIKTFQDLGAKNLEPIEVNILLKHPYIQDLITNYVDYKIPDIKMILQRSEHAQGSDGERSPSRLTDEKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C9J3-1", "uniprot_id": "SPEF2_MOUSE", "id": "Q8C9J3-1", "name": "Sperm flagella and cilia-associated protein 2", "aln": "MSEILCQWLNQELRVSRTVSPKSFAKAFSNGYLIGEVLFKFELQSDFAEFSESRGSTAKLNNFSRLQPTLHLLGLQFDQNVAQSIITEKPGAATKLLYQLYIALQKKKKTGLTGLEIQTMQPQTNLRLQTLKSEAFRE---------------------------------------------------------QRLNRRRQNEIMAKIQAAIIQIPKPESNRTLKAIEAQKLMKKKKEAEDVANEIKKFEALIKKDLQIKESVSKTSLETTDQTTAELLNTYSDDDYIKKIQKRLEEDAFAREQREKRRRRLLMDQLMAHEAQEEAYREEQLIHRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQFEERRLKDFQDALDREAALAKQAKIDFAEQTLREKEIHEKISVERAQQRYKKHYGICAEILDQMLDLCTKVADYRLLTNNLIPHKMMHDWKELFFSGIPIYEQTSLTHGQTEPTEDHRAEVKKRNLLDSKDYEDYKNMVGEWALPEDMVNSSPPSNNSILGHVLLRLIEKADPSASNAEATELPSLAVKGCILGKTLSGKTTVLKSLQNDFPVHVLSIDTLVQEAIQAFHERQKSGKTPPTQEDDKRDPV-VNQEKVSKTQD-KNVLAVSPVPGDRTSQKE--------GVKINEFEQFRSSDSFLSLSMRAQLGAKSELMLRRGKSIPDILLVSILVNAIKEIPVDQSWVLDGFPITLNQAKLLEEALTGYKRKFLQLKKKKEQMPTLALDPSTSTEVSLLPSALDFVILLDISDNSSLARTN-------------DIIAKEISHEISHENVGRPGTGTSQ-DNKSEDRNL-RDHIQHRIVGFLDNWPLLEEWFTQPKNILTKVNAEIDEALLCQKVKEIFATETVNKKIKVEKTLEEKETEKKAGAPPAEPPAMSPPLSS--EAEKDKELHQAKTP-----GKGKTQS-------------------------VSPKGKAQGGKVSVKKSPVGSAEVSPTPTAPPPPKAGTEEWVYVNEPIPEELPSFLVPYWELIEKSYINHIKTVLRHLRERQHNVLSYLYETRTSFQEFLRRPDHKQDFVSQWQADFNSVPEDLWEDEETKAELHQRVNDLRDRLWDICEARKEEAEQERLDIINESWLQDSIGITMNHFFSLMQAEVNRFQDTKRLLQDYYRAMESKIPLEDSKKFTRVPLVQLDGK---EISESQLRIPLVPRISNSPENSA-----VKPKVGTFLKGRSDPPLEVLEANFEIDEKILLDTWQQASLAISNMVAAEVHQRLTEEEKEPPQLDSKEKSPQSGANKKAKKEKE---------------------APKKKKTDKKGKGKSSPVAEVSPVTVTPEEMAEMEKRNELRLRIKEEHLAALQTEEQAAQFRLELIKLKALSVLEDLVTKVIDVYRLMEKWLGKRYLNEMASIQKLTELARYHIETATKIQNEIYLSQEDFYINGDIKVFPDPSPPTRPPPVEREENGTLTIEQLDNLRDQFLDMAPKGIIGNKAFSDILLDLITLNLGTNNFPSSWMHLSQLDLQEITSLLTVNTEFVDWRKFLMVTAMPWPMALEDELLDTLQRFKALDEAQTGTITYEQYKQAGLWFSGDEDIKIPENPLEPLPFNRQEHLIEFFFRLFADCEKEPPQLDYTQMLLYFACHPDTLEGVYRALSVAVGTHIFRQVETPMLMAEKTSISTVSPIEEFPETEESSAKEDRELKEE--KDDQKEEEIPENANTEKISMETLLKVFGGGNE-VLDANRFASYLKSENIYAENFIKTFQDLGARNLEPIAVNILLKHPYIQDLIANYVDYKFPDIKMILQRSEHAQGSDGERSPSRLTDEKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C093-1", "uniprot_id": "SPEF2_HUMAN", "id": "Q9C093-1", "name": "Sperm flagella and cilia-associated protein 2", "aln": "MSEILCQWLNKELKVSRTVSPKSFAKAFSSGYLLGEVLHKFELQDDFSEFLDSRVSSAKLNNFSRLEPTLNLLGVQFDQNVAHGIITEKPGVATKLLYQLYIALQKKKKSGLTGVEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHDWKELFFNAKPIYEQASVKTLPANPSREQLTELEKRDLLDTNDYEEYKNMVGEWALPEEMVDNLPPSNNCILGHILHRLAEKSLPPRAESTTPELPSFAVKGCLLGKTLSGKTTILRSLQKDFPIQILSIDTLVQEAIQAFHDNEKVSEVLPIQKNDEEDALPVLQEEIKESQDPQHVFSAGPVSDEVLPETEGETMLSANADKTPKAEEVKSSDSFLKLTTRAQLGAKSEQLLKKGKSIPDVLLVDIIVNAINEIPVNQDCILDGFPMTLNQAQLLEEALTGCNRNLTEVERKKAQKSTLAIDPATSKEIPLPSPAFDFVILLDVSDTSSMSRMN-------------DIIAEELSYKTAHEDISQR-VAAEN-QDKDGDQNL-RDQIQHRIIGFLDNWPLLEQWFSEPENILIKINAEIDKESLCEKVKEILTTEIAKKKNKVEKKLEEKEAEKKAAASLAELPLPTPPPAPPPEPEKEKEIHQSHVASKTPTAKGKPQSEAPHGKQESLQEGKGKKGETALKRKGSPKGKSSGGKVPVKKSPADSTDTSPVAIVPQPPKPGSEEWVYVNEPVPEEMPLFLVPYWELIENSYINTIKTVLRHLREDQHTVLAYLYEIRTSFQEFLKRPDHKQDFVAQWQADFNSLPDDLWDDEETKAELHQRVNDLRDRLWDICDARKEEAEQERLDIINESWLQDTLGMTMNHFFSLMQAELNRFQDTKRLLQDYYWGMESKIPVEDNKRFTRIPLVQLDSK---DNSESQLRIPLVPRISISLETVT-----PKPKTKSVLKGKMDNSLENVESNFEADEKLVMDTWQQASLAVSHMVAAEIHQRLMEEEKENQPADPKEKSPQMGANKKVKKE-----------------------PPKKKQEDKKPKGKSPPMAEATPVIVTTEEIAEIKRKNELRVKIKEEHLAALQFEEIATQFRLELIKTKALALLEDLVTKVVDVYKLMEKWLGERYLNEMASTEKLTDVARYHIETSTKIQNELYLSQEDFFINGNIKVFPDPPPSIRPPPVEKEEDGTLTIEQLDSLRDQFLDMAPKGIIGNKAFTDILIDLVTLNLGTNNFPSNWMHLTQPELQELTSLLTVNSEFVDWRKFLLVTSMPWPIPLEEELLETLQKFKAVDKEQLGTITFEQYMQAGLWFTGDEDIKIPENPLEPLPFNRQEHLIEFFFRLFADYEKDPPQLDYTQMLLYFACHPDTVEGVYRALSVAVGTHVFQQVKASIPSAEKTSSTDAGPAEEFPEPEENAAREERKLKDDTEKREQKDEEIPENANNEKMSMETLLKVFKGGSE-AQDSNRFASHLKIENIYAEGFIKTFQDLGAKNLEPIEVAVLLKHPFIQDLISNYSDYKFPDIKIILQRSEHVQGSDGERSPSRHTEEKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JJ34-1", "uniprot_id": "A0AC58JJ34_DANRE", "id": "A0AC58JJ34-1", "name": "", "aln": "MSDIICQWLNSELRLSKVVEPHSFARDFSNGYLIGEILYRYELQDDFHLFSKQNTSNAKLNNFTRIEPTLQLLTVPFDLTMAKAVMLGRHGAATRLLYQLYILLQRKKRAGLTATAMEVMQPAATARLHRIENSIYTERLKTVVKREADLKMQKIAKRFHKRGQEMFSRSVMTELLKEEDRLKRQEERRLRDIEKHRQARRKQNEIMIQIQSAVVQIPKPPHIRTSRASEKQQQFRKKQEAQHVHREIAQFEKKKKTTSPPEGGALLFSGRVTQPMSTGDKAQWN-KDYIENIRQRLEEDATAREQREMRRRRALMEQLQAHEAQQEALREEQMVSRLMRQTQQEKRITVQLMQIKQQKEVLRENRIFQERQYQERRQRDFQEALDREAVLAQQERLERSEQLRIEHELHKQLAEERAQARYQKHFGICRDILGQIVDLATKAGEYRLLTANLIPVKLMQEWMELFYSGKPLYEVACVDPKPTEPSPEQIIELEKLQILNNQDYDEYVAMIGEWALDAETERQTNAGNSDILDHVLNRLRNMIVPPTVSTPPPLFPRFTIRACMLGKTFSGKTTCLSRISSTLNIHVLSANTLIQDALSAYQQEKQAASESQNEKSLEKNVSQTEHTTEQLQKD--EQETSSPLESGPQPHEA--------SSGLHEKEDKEESKAIPKWSSRAQHGAAVEKVLRTGQAVPDQLLVDIIVDAIRNIPADSGWILDGFPVDISQAQMLEKALN-----MTELDGTKTQN-NLSTTKNGPKDAAPPSPALDLVVLLDVSDEQVLERATTQPPEGTQIVNGESIKQEKGSSDAAEENTSMPDLNTQDPESLSDDKSLGRTQIQFRISGFHQTWPKLEKWFGDQQNILVKVTAGVDKDTLFSNVETILRDSIES----VEKGAALADTRR----------------------------------------------------------------------------------ASVTSTPEQTRPESACSSKSSRATPKSARRSFAEEPLPKELAEYLVPYWENVCSSYVTNVKTVMQNLRGERELIIHHLYNIRENFRQYLQKPDLKQEFVSSWQRDYNSVPDNIREDEETKGELHQRLDDLRERLWDISDKRKEEAEQEKAGVIHDGWLEDHTAVLINNYSALMQIEVGRFQDCVCLLKDHYSTMG-KTAFESKCDFARVPLLDITADQHVDESKISESAPSEKSVKNAEEKDSEIVDRMKTKVFPLVSCRSPTSEILKQPLHQADENLLQEFFQAAIAIFRSMVSAEMRQWDEEEVDEDQKQMEAQKAQTLTSATDVRKAG-------------------------------KQKGAPPPPPPPEPSPQPAARNPEELRKRAEKKRFKQELSAALKPEENAVKQRLELVKAHGLRTVISLQHKAEQVYRNMEEWMKARYLAEMKSIDQLTDLVRQHIETGVQIRHELVLQSTDFCVDGDTRVLLSPELAPRRSLLEQPKNSTLTVQQLHVLCTQLRKIAPTGLMCRSELTEALHELTSAHMGTDVLPEAWMHITPSQVEELVCILAQDSEMLDWRQFLLSAALPWPFPTQTQLIKTLQRYRDIDTTGNGLITQEQYEQVELWFPSEQDASVPDDPTEPVPYDRLANLKKFFFSLFASTHSSPLLLDYLMMLLYFCCHPEAAQGFTRALSLITGHTLHYKHTTPLT-------------QSVPCLEGAGVVDDAGADNE---EEQHRGVESEDVG---VSVDDVLRVLSHGEDLVLHLNRFQPVHRSRDELREELLKVFKELGFSVEEKIPFSTLSQHPFLQDLMEGSSQYLLHDIHKVFQT----RQTEDSRSFST------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*:*****.**::*:.*.*:***: **.***:**:*.::***.** * ... *.******:*::***:** : ** .:*:.:: : *.**:******* **:**::***. ::.** :. **: ::.. : * : **:***** :**:*::***** ** :* * *: ::**:**:.* ** :** *. . . * . :: :. .:**::*::****** ****** ***: **:** *****:** ****:: *****:***:**:****:::::**** :****:*:*.:*** :***:******.*::* ::: ** :.:*.::: **** **:**:.:* :**.*::**.**..:**:** **** *:*::* ***:.. *:** :. ::.: :: *::* ::*:.:**::* * ***** : . ..*. **.*:* ** : *. . . :* ::::.*:****:***** * :.. : :::** :**:*:*:.*::: :: .. .:. : : . : :* . : : . .. . . *: . *.:: . : *** ** * :*: *:::** ***.*:*:**.:**.:.. :*****: :.**::**:**. ::. .* * .*: ..: . ..*:*:.:***:** . : * . .* :: * . :.*: . :.. :. . *:.* * :**.** ** :.** **:** : .*** *:.* :*: * .::: *: . . *** ::.: .*..:* : *. ... : . :. **:*:*:. :****** : .:*:. :***:::** :. :: :**: * .*:::*::** **:**:.** *:**:*::: :*****.*****::***:*****.: ********: .:*::.**:* .: :*:: :*** *:.**** **:*:* * : ..*.. *:*:**::: .. : *: . * :. : *. : :.*. ..:. : . :. .: **::: : :* * . **:**::* ** .* :*: : ...:* * ** ..* * .. . .* ::. : ::*:* ***: ** *.: ****:* :.* : .* *. :**: **:*: *** ** * ::**::.* ****..:*::*: *.. ** ::*: :*: .* . * . :*: ::.***::**. * *: .:**.*:: .. ::: * :* : ::**: :.. ***:: :::*:..:*: ::*::***:**: :::***:. : :*:.***::: * * ** *** *. ***..::* .:*::* **:*::* :* :*** ***. ...* *** *****.***:: :*. ****: .* :. : :.: :..* * .. :: ..: :*: .*:.. :*:: :*:*: *.: . . *** . : .: * ::*.*::** * * . * :**::***: . :* : **: ::* : ::..** * ", "identical_positions": 577, "similar_positions": 594, "identity": "30.86%" }, { "cls_id": "homologset.agr.RGD:620451", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88298-1", "uniprot_id": "RHD_RAT", "id": "O88298-1", "name": "Blood group Rh(D) polypeptide", "aln": "MGSKYPRSLRCCLPLWAFGLQVTFILLFYFLIGQDPIQA----------DHK-FMAIYQVIQDLTLVAALGFGFLSSSFRRHGWSSVAFSFFMLALGVQGTILLDYFLNWVLDWNMIKNPFSPFLSIQRATISTLPLLISAGAVLGKVNLVQLAVMVLVEAMTFGAIRVADKKVFRIEDHIIMMYGHVFGAYFGLTVAWWLSKSLPRRRHENAQTEKVQMTTSSSLFAMLGTLFLWIFWPSINSALLEG-TKKKNAVFNTYYALAVSTVTATSMSALSHPKGKINMVHIHNAVLAGGVAVGAPSCLISSPWIAMVLGLTAGLISIWGAKCPQ-VCLSDLL--LNPSGIHYTFGLPGLLGALTYYCLHIIAES------------------RPSNLWIVT-------QTITDVGALSFAMAMGMVTGLLTGCLLSVKVWRAPHAVKY-FDDQAFWEFPHLAVEF----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CF94-1", "uniprot_id": "RHD_MOUSE", "id": "Q8CF94-1", "name": "Blood group Rh(D) polypeptide", "aln": "MGSKYPRSLRCCLPLWALELQTAFSLLFCFFIPHDTAQV----------DHR-FMASYQVLRNLTLMAALGFGFLSSSFRRHSWSSVAFNLFMLALGVQGTILLDHFLGQVLQWNKINN----LSSIQIATMSTLPVLISAGAVLGKVNLVQLTVMVLMEAMAFGAIRFADEKVFKMTEHIIMMHGHVFGAYFGLTVAWWLSRSLPRRVGENAQTEKVQMATSSSLFAMLGTLFLWIFWPAINSALLEG-TKKRNAVFNTYYALAVSAVTATSMSALSHPQGKINMVHIHNAVLAGGVAVGAPGCLISSPWISMVLGLIAGLISIWGAKCPR-ACLNHML--QNSSGIHYTFGLPGLLGALTYYCLQIVTEP------------------KSSDLWIIT-------QTVTHIGALSFAVAMGMVTGLLTGCLLSVRVWRAPHAAKY-FDDQTFWEFPHLAVGF----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18577-1", "uniprot_id": "RHCE_HUMAN", "id": "P18577-1", "name": "Blood group Rh(CE) polypeptide", "aln": "MSSKYPRSVRRCLPLCALTLEAALILLFYFFTHYDASLE----------DQKGLVASYQVGQDLTVMAALGLGFLTSNFRRHSWSSVAFNLFMLALGVQWAILLDGFLSQFPPGKVVIT----LFSIRLATMSAMSVLISAGAVLGKVNLAQLVVMVLVEVTALGTLRMVISNIFNTDYHMNLRHFYVFAAYFGLTVAWCLPKPLPKGTEDNDQ-----RATIPSLSAMLGALFLWMFWPSVNSALLRSPIQRKNAMFNTYYALAVSVVTAISGSSLAHPQRKISMTYVHSAVLAGGVAVGTSCHLIPSPWLAMVLGLVAGLISIGGAKCLP-VCCNRVLGIHHISVMHSIFSLLGLLGEITYIVLLVLHTV------------------WNGNGMIGF-------QVLLSIGELSLAIVIALTSGLLTGLLLNLKIWKAPHVAKY-FDDQVFWKFPHLAVGF----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02161-1", "uniprot_id": "RHD_HUMAN", "id": "Q02161-1", "name": "Blood group Rh(D) polypeptide", "aln": "MSSKYPRSVRRCLPLWALTLEAALILLFYFFTHYDASLE----------DQKGLVASYQVGQDLTVMAAIGLGFLTSSFRRHSWSSVAFNLFMLALGVQWAILLDGFLSQFPSGKVVIT----LFSIRLATMSALSVLISVDAVLGKVNLAQLVVMVLVEVTALGNLRMVISNIFNTDYHMNMMHIYVFAAYFGLSVAWCLPKPLPEGTEDKDQ-----TATIPSLSAMLGALFLWMFWPSFNSALLRSPIERKNAVFNTYYAVAVSVVTAISGSSLAHPQGKISKTYVHSAVLAGGVAVGTSCHLIPSPWLAMVLGLVAGLISVGGAKYLP-GCCNRVLGIPHSSIMGYNFSLLGLLGEIIYIVLLVLDTV------------------GAGNGMIGF-------QVLLSIGELSLAIVIALMSGLLTGLLLNLKIWKAPHEAKY-FDDQVFWKFPHLAVGF----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53390-1", "uniprot_id": "MEP3_YEAST", "id": "P53390-1", "name": "Ammonium transporter MEP3", "aln": "-MARGDGHLWTETYDSSTVAFMILGAALVFFMVPGLGFL----------YSGLARRKSALALIWVVIMATLVGILQWYFWGYSLAFSKTATNNKFIGNLDSFGFRNVYGKISDDSTYPELIYAIFQMMFMCVA-LSIIAGATAERGKL-FPHMVFLFVFATLVYCPITYWIWAPGGWAYQWGVLDWAGGGNIEILSAVAGFVYSYFLGRRKENLLIN--FRPHNVSMVTLGTSILWFGWLLFNAASSLSPNMRSVYAFMNTCLSATTGGMTWCLLDYRSEK-KWSTVGLCSGIICG-LVAATPSSGCITLYGSLIQGIIAGVVCNFATKIKYYLKVDDSLDLLAEHGIAGVVGLIFNALFAADWVIGMDGTT------------------KHKGGWLTHNWKQMYIQIAYIGASAGYCAVVTAIICFVLGKIPGVHLRVTEEAEALGLDEDQIGEFAYDYVEVRRDYYQWGVDTDALHTTCNGANSASETNPTEDSQNSSLSSATVSGQNEKSNNPKLHHAKEA---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40260-1", "uniprot_id": "MEP1_YEAST", "id": "P40260-1", "name": "Ammonium transporter MEP1", "aln": "MESRTTGPLTTETYDGPTVAFMILGAALVFFMVPGLGFL----------YSGLARRKSALALIWVVLMATLVGILQWYFWGYSLAFSKSAPNNKFIGNLDSFGFRNVYGKKFDEDAYPELAYATFQMMFSCVN-LSIIAGATAERGRL-LPHMVFLFILATIGYCPVTYWIWSPGGWAYQWGVLDWAGGGNIEILSAVSGFVYSWFLGKRNEKLLIN--FRPHNVSLVTLGTSILWFGWLLFNSASSLSPNLRSVYAFMNTCLSAITGGMTWCLLDYRSEK-KWSTVGLCSGIISG-LVAATPSSGCITLYGSLIQGIVAGVVCNFATKLKYYAKVDDAMDILAEHGVAGVIGLIFNALFGADWVIGMDGTT------------------EHEGGWVTHNYKQMYKQIAYIAASIGYTAAVTAIICFVLGYIPGMRLRISEEAEEAGMDEDQIGEFAYDYVEVRRDYYLWGVDEDSQRSDVN-HRVNNAHLAAERSSSGTNSSSDGNGEMIQSEKILPIHQEDPANR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A6M3Q9I2-1", "uniprot_id": "A0A6M3Q9I2_DROME", "id": "A0A6M3Q9I2-1", "name": "", "aln": "---MHSPAAKVSGYVVLMIVQIIFLVLFWLFVRYEKTALPLAIDAEDAGSANEHVSKYPQFQDIQVMIFIGFGFLMTFLRKYGYSATGFTLFMAALVVQWAVLMKGFLHME-GGKISLS----LENIIDADIAAAVPLISMGALLGRTTPIQLLCMSVFEVALFAANEYLALHVFSICDCGGSITVHAFGAYFGLAVALMLRPASDQNETGKLEG----ASYTSDIFAMIGTTFLWVYWPSFNSVLADG-AGGERAILNTFLSLAAATVTTFVVSALVSHENKLDMVHVQNSTLAGGVAVGTVCNLLLGAHGAVLIGIIAGTVSVLGYRYLT-PWMTANLRLHDTCGVHNLHGMPALISAIASAIYASMATVGEYQSELQDIFPAMVGTNGTETKIMGGLGRNATSQAGYQLFGIAVTLLIAIGGGILTGAVLKYTNFRNLKKDEH-HQDEHYWEVPAAENKEEYLNMLAKLLDDDAAATNSNSQSAANFNWRPFLLRNWNAIVPANNLYVRGALH-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: :: .*:* : :. : : :. : . . .: : : . * *: :: : :. . . *:.. : . : . :*: :**. * .*:. . : . * : : : * . . : .. :.* :...: ::: *: ** :. . : : : .: : * . : :: * : . ::: :.. ", "identical_positions": 18, "similar_positions": 88, "identity": "3.42%" }, { "cls_id": "homologset.agr.RGD:620452", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51672-1", "uniprot_id": "XCL1_RAT", "id": "P51672-1", "name": "Lymphotactin", "aln": "MRLLLLTFLGVCCFAAWVVEGVGTEVLQESICVSLRTQRLPVQKIKTYTIKEGAMRAVIFVTKRGLRICADPQAKWVKTAIKTVDGRASASKSKAETIPTQAQRSASTAVTLTG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47993-1", "uniprot_id": "XCL1_MOUSE", "id": "P47993-1", "name": "Lymphotactin", "aln": "MRLLLLTFLGVCCLTPWVVEGVGTEVLEESSCVNLQTQRLPVQKIKTYIIWEGAMRAVIFVTKRGLKICADPEAKWVKAAIKTVDGRASTRKNMAETVPTGAQRSTSTAITLTG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47992-1", "uniprot_id": "XCL1_HUMAN", "id": "P47992-1", "name": "Lymphotactin", "aln": "MRLLILALLGICSLTAYIVEGVGSEVSDKRTCVSLTTQRLPVSRIKTYTITEGSLRAVIFITKRGLKVCADPQATWVRDVVRSMDRKSNTRNNMIQTKPTGTQQSTNTAVTLTG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UBD3-1", "uniprot_id": "XCL2_HUMAN", "id": "Q9UBD3-1", "name": "Cytokine SCM-1 beta", "aln": "MRLLILALLGICSLTAYIVEGVGSEVSHRRTCVSLTTQRLPVSRIKTYTITEGSLRAVIFITKRGLKVCADPQATWVRDVVRSMDRKSNTRNNMIQTKPTGTQQSTNTAVTLTG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*::**:*.::.::*****:** .. **.* ******.:**** * **::*****:*****::****:*.**: .::::* ::.: :. :* ** :*:*:.**:****", "identical_positions": 60, "similar_positions": 41, "identity": "52.63%" }, { "cls_id": "homologset.agr.RGD:620453", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63342-1", "uniprot_id": "M2GD_RAT", "id": "Q63342-1", "name": "Dimethylglycine dehydrogenase, mitochondrial", "aln": "MLRLGALRLRGLALR-----SSQGRPSSAGLREGQESPPSPPE--WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBT9-1", "uniprot_id": "M2GD_MOUSE", "id": "Q9DBT9-1", "name": "Dimethylglycine dehydrogenase, mitochondrial", "aln": "MLRPGALRLRGLALR-----GSPRRPSSAGLREGQESPASPPE--WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLMEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMNKILAGLYNPGDGHIDPYSLTMALAAGARKYGALLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVTHGVPPGFGKELFESDLDRISDHLEAAMEMIPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVATGFGYGIIHAGGVGKFLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKTLKSKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGRDSTQLLDHLFANVIPKVGFTNISHMLTPRGRVYAELTVSQQSPGEFLLITGSGSELHDLRWIEEAAFRGGYDVEIQNITDEFGVLGVAGPYARRVLQKLTSEDLSDDAFKFLQTKSFNISDIPVTAIRISYTGELGWELYHRREDSATLYERIMSAGQEEGIGDFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKTEGLKRRLVCLTVATDDVDPEGNESIWYKGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPATIIQEPLVLTEPARARLQKDGKKTNLEKGPSRTTKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI17-1", "uniprot_id": "M2GD_HUMAN", "id": "Q9UI17-1", "name": "Dimethylglycine dehydrogenase, mitochondrial", "aln": "MLRPGAQLLRGLLLRSCPLQGSPGRPRSVCGREGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGKDKT----------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** **** ** .* ** *. ***:*.*. ..* ****************************:****:**************************************:*********************** ************.*******:******:*:******:*:**********************:**** *.************.*.************:**********************:****************.****************************************:* ***::****************** :*::*****:**********:*************************** **************:*****************************************************************: *:************************************.*************.* ************:** :***** ******************:**********:************************ *.:*******:*****:******** **:*************.********:::*:*************************.:**: **.*******.:*****:************* *************:**:******** *********::**********:************:**:***:***********************:*******************.***********:* ****.* * ", "identical_positions": 761, "similar_positions": 69, "identity": "86.87%" }, { "cls_id": "homologset.agr.RGD:620454", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VNU2-1", "uniprot_id": "Q9VNU2_DROME", "id": "Q9VNU2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------MHTFKRG----FFCSDLSIRYPYKDCTITV-----PMLLLMMLLLPMLFVAVVEIM--RICKR------------FRTRLYFRNLWRAEATFSFGFIATYLTTELAKHAVGRLRPHFFHGCQP--RLDDGSSCSDLQNAEL--YVEQFHCTN--NNLSTRQIRELHVSFPSAHSSLSFYSMVLLALYVHGV-WRGRGGVRVLRHVLQFLLLMAALCVSLSRVADYWHHWSDVLAGALLGVTYAAITAAYVG---NLLRRQTSSTGRIPPSLNYSHHLHHQLMADNNNSTASAKVHFLAAAASASMTTTTPLDDIQDSDVEDSRDCRDSEDSHDSQDSHAENEDDNEEVYKSQMSRPVTPPTDLTHVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNT9-1", "uniprot_id": "Q9VNT9_DROME", "id": "Q9VNT9-1", "name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "aln": "---------------------------------MRDAPEDQSVTVSMPASASGSAAGSTGPSS-------------------------DRRMTQRLLVELLVVVVLVIPICVYEFAVDPVRRG----FFCDDESISYPFQDNTITP-----VMLGLIVGLLPALVMVVVEYV--SHLRAGDISATVDLL-GWRVSTWYVELGRQSTYFCFGLLLTFDATEVGKYTIGRLRPHFLAVCQP--QIADGSMCSDPVNLHR--YMENYDCAG--EGFTVEDVRQARLSFPSGHSSLAFYAMIYVALYLQRK-ITWRG-SKLSRHFVQFAVVMVAWYTALSRVMDHWHHWSDVLSGSLLGVAGALITAHYIA---RMFDDGAS-----------------------NILSGGLRRENTAATLQEEVCPTTPPPYSVNNSFSEDQYCSKV---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNU1-1", "uniprot_id": "Q9VNU1_DROME", "id": "Q9VNU1-1", "name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "aln": "-------------------------------------------------------------MS-------------------------KYSKLARGFCDLLIWVALSVASVLLHKMGRPFRRG----FFCGDETLSYPARDGTISS-----KVIIAIVLGVPNAVIVVVELF--RQLPGGPLREAGGKRDSCRIAHRLGVLYRQVIFYLYGLAMVTFTTMLTKLCLGRLRPHFLAVCQP--MLPDGSSCQDAQNLGR--YIDSFTCSN--ANMTDYQFKELYQSFPSGHASMAMYAMLYLAIYLQAA-LSTRV-SKLLKHLLQFLFVMFGWYVSLTRIIDYYHHWSDVLAGAALGVVFAWLTSAYVA---DLFAGKRWP-----------------------KTGYSANTLRKPQVSPKSSTKSQAGGSTSGAGQPPALPAYTFGTLPYLAAHPAQAQAQYAQPYHNYGYVP-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P97544-1", "uniprot_id": "PLPP3_RAT", "id": "P97544-1", "name": "Phospholipid phosphatase 3", "aln": "---------------------------------MQSYKYDKAIVPESKNGGSP----------ALNNNPRKGGS--------------KRVLL-ICLDLFCLFMAALPFLIIETSTIKPYRRG----FYCNDESIKYPLKVSETIN-----DAVLCAVGIVIAILRIITGEF--YRIYYLKEKSRSTIQN-----PYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCDP--DFSQ-------INCSEG-YIQNYRCRG--EDS---KVQEARKSFFSGHASFSMFTMLYLVLYLQAR-FTWRG-ARLLRPLLQFTLLMMAFYTGLSRVSDYKHHPSDVLAGFAQGALVACCIVFFVS---DLFK------------------------------TKTTLSLPAPAIRREILSPVDIMDRSNHHNMV-----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JY8-1", "uniprot_id": "PLPP3_MOUSE", "id": "Q99JY8-1", "name": "Phospholipid phosphatase 3", "aln": "---------------------------------MQSYKYDKAIVPESKNGGSP----------ALNNNPRKGGS--------------KRVLL-ICLDLFCLFMAALPFLIIETSTIKPYRRG----FYCNDESIKYPLKVSETIN-----DAVLCAVGIVIAILAIITGEF--YRIYYLKEKSRSTTQN-----PYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCDP--DFSQ-------INCSEG-YIQNYRCRG--EDS---KVQEARKSFFSGHASFSMFTMLYLVLYLQAR-FTWRG-ARLLRPLLQFTLLMMAFYTGLSRVSDYKHHPSDVLAGFAQGALVACCIVFFVS---DLFK------------------------------TKTSLSLPAPAIRREILSPVDIIDRNNHHNMV-----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14495-1", "uniprot_id": "PLPP3_HUMAN", "id": "O14495-1", "name": "Phospholipid phosphatase 3", "aln": "---------------------------------MQNYKYDKAIVPESKNGGSP----------ALNNNPRRSGS--------------KRVLL-ICLDLFCLFMAGLPFLIIETSTIKPYHRG----FYCNDESIKYPLKTGETIN-----DAVLCAVGIVIAILAIITGEF--YRIYYLK-KSRSTIQN-----PYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCNP--DFSQ-------INCSEG-YIQNYRCRG--DDS---KVQEARKSFFSGHASFSMYTMLYLVLYLQAR-FTWRG-ARLLRPLLQFTLIMMAFYTGLSRVSDHKHHPSDVLAGFAQGALVACCIVFFVS---DLFK------------------------------TKTTLSLPAPAIRKEILSPVDIIDRNNHHNMM-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V576-1", "uniprot_id": "WUN_DROME", "id": "Q9V576-1", "name": "Putative phosphatidate phosphatase", "aln": "MPAVKIIMSTETSASETTPLRRSENETPDHKELAQSNSNSRQTTVNSNNNNYSNSV-----QVRLQEQDRDSDSEQQQHTATITMDTNKRILCRVGLDVLILLCAGFPILLFFLLG-EPYKRG----FFCDDESLKHPFHDSTVRNWMLYFIGAVIPVGVIFIVEVIISQNK--AKQDNGNATSRRYVFMNYELPDWMIECYKKIGIYAFGAVLSQLTTDIAKYSIGRLRPHFIAVCQP--QMADGSTCDDAINAGK--YIQEFTCKG--VGSSARMLKEMRLSFPSGHSSFTFFAMVYLALYLQAR-MTWRG-SKLLRHLLQFLFIMVAWYTALSRVSDYKHHWSDVLAGSLIGSISALVVANYVS---DLFQ------------------------------KPNTKPYLARTVQDMNASPAQAITITTN---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNT8-1", "uniprot_id": "Q9VNT8_DROME", "id": "Q9VNT8-1", "name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "aln": "----------------------------------MSFNLS------------------------------------------------LRPPIRLLVDLVLLGLLIVLVENFRRLWGPPTKRG----FFCDDESLMYPYHENTVSP-----TLLHWLGLYLPLISLVVLESF--LSHRKDMAP-----------WPTLWPVYNTVRWFLYGYVSNDLLKGIGKQALGRLRPHFFAVCSP--HFPDGSSCLDESHRGALKYHTDYECRPNLSQATEEMIRDVNVSFPSGHSAMAFYGLVFVALHLRRRRWPLRG--SLLSPVLQLACVALAWFVAISRVIDYKHHWSDVAAGSLLGAGSALAVTRAAASEEL-----------------------------------QWRCQDSLASAKQEAAVVDVADVKGGQQMPHDLSLVTCHISN-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNU0-1", "uniprot_id": "Q9VNU0_DROME", "id": "Q9VNU0-1", "name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "aln": "----------------------------------------------------------------------------------MCGNPNTRLLSRLVIDFLILLGIYGAALVVLPQQLSTAQRG----FHCSDTSLKYPYRQPWLTK-----VHLTIAVVALPAAFVLVVEMLRAAVVPSSTELTQRFVFVGVRIPRFISECYKAIGVYLFGLGLTLAAIRLTKHSTGRLRPYFFDICQPTWGTEGGESCSDVTAQNSTLYLEDFSCTE--FAASQDLLALVRHSFPSGFVSTTCYAMGFLIFYSQAR--LFAPWLRLVRASLQLACCSLALVVCWERISTYQNHLTDVAAGAALGGWMAFFATVFVAH-----------------------------------LFVEVRVKRRPMPRNEQIYGYAGYYTRATYGY------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04396-1", "uniprot_id": "LPP1_YEAST", "id": "Q04396-1", "name": "Lipid phosphate phosphatase 1", "aln": "---------------------------------------------------------------------------------MISVMADEKHKEYFKLYYFQYMIIGLCTILFLYSEISLVPRGQNIEFSLDDPSISKRYVPNELVG----PLECLILSVGLSNMVVFWTCMFDKDLLKKNRVKRLRERPD--GISNDFHFMHTSILCLMLIISINAALTGALKLIIGNLRPDFVDRCIP-----DLQKMSDSDSLVFG--LDICKQTN------KWILYEGLKSTPSGHSSFIVSTMGFTYLWQRVF--------TTRNTRSCIWCPLLALVVMVSRVIDHRHHWYDVVSGAVLAFLVIYCCWKWTFT--------------------------------------------NLAKRDILPSPVSV---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * .* :: : * *.*** *. * * . * *.. : : : : : . . *: : :* ** :* . ", "identical_positions": 19, "similar_positions": 21, "identity": "3.93%" }, { "cls_id": "homologset.agr.RGD:620455", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1L1STQ7-1", "uniprot_id": "A0A1L1STQ7_MOUSE", "id": "A0A1L1STQ7-1", "name": "", "aln": "MPGASEMKDGPEQEQRHRAGHTWKHGIRASSWLAVGNSQEKSPSVDCRSSHRTLGFSRTGVCLHTAILPTEDNGLNLWKQKGLHLGNRGSDWKTNIIVDQDTDYAELVLFIGEITLGEKNRNSMKDIQLRRKEAKSILQAVCTLLNSGGGVVKAHIKNQNYSFTRDGMGLDLVNSLPGIMHLPHDYLDFMQHKDYFFVFVKPLKPNQKGPGITTLKTNLYRRINSISDEVKVANAVQLLKSRTDPEEKAESRPSSPGKIVCNETLN----ECLS--LFNRDWLAYEETFCFTKSIHAEVKLTPKEKIFPKEKILELLPQTVSAFANTDGGFLFIGLDGKTQQIIGFEAEKSNLVLLESEIEKCIQQLPVTHFCGEKEKIKYTCKFIEVRKSGAVCAYVCALRVERFCCAVFAAEPESWHVEGGCVKRFTTEEWVKRQMDATA-----------------------------------------VMPGKVICCPEALYMKPFSQHEGYEHLVRTELGSLLKGTLVISKSWALDLGLQEKQEVIWDVLHISQGSLLTLYVFVQGDENLEGNSSLLGELGAELKGYYKQIALTLKQMLLNHCGYTAEIGIIVKITYLGH--KTMCLYDTSTKIRYPQKYYLSA--KAVKDLEKALVEILGSYESFYSLPRRNWDSFMSAFLNVGSYIVPVLRNV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K4S0-1", "uniprot_id": "A0A0G2K4S0_RAT", "id": "A0A0G2K4S0-1", "name": "", "aln": "-----------------------MAGNLPRLVEDVNPQTFTEPSVQLKCPGNIFQGGR-----HAKPGSWKDS------QKGFHLGSRDSNCKMSITVDQDTDYAELVLSIGEITLGEKTRKSMKDSQRRKREAKTFQQAVCTLLNSGGGVAKARIKNQNYDFSRDGVGQDLENFLPHILDFPHEYLDFKQVKDYFLMFVKAWKLKQKGPGITTLKTNLYIRSISSSIELKAVNAVKFLKS----------RLSSPGTIVCNEVLN----ECLN--LFNRDCFTCKEKFCFTKATHAEVKLTPKE------NILEILPQTVSSFANADGGYLFIGLDGKTQEIIGFEAEKSDLVHLESEIEKCIRQLPVTHFCEEREKIKYTCKFMEVHKPGAACSFVCALRVERFCCAVFAAEPESWHVEDSCVKRFTAEDWVKRQMDGPA-----------------------------------------LISGKVISSPEALCGKLFSTQEAHEQLLWAQLDSLPKGTLVVTKRWALDLPLQDKHGVILDTLHIPQDSLLTLHGFVLGGEDLEDDSTLLRELGAELKGYYKQTAVTLKQTLANHGSYTEKIGIAIKITYLGHN-KAVSLYDSSSKIHYPTKYYLTT--ETAKNLEKALAEILGS----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYM2-1", "uniprot_id": "SLN12_HUMAN", "id": "Q8IYM2-1", "name": "Ribonuclease SLFN12", "aln": "---------------------------------------------------------------------------------------------MNISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRITTLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQ--RIKEILPQYVSAFANTDGGYLFIGLN-EDKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINTSLPAPHSWPLLEWQ-----RQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQD-------------EEFKGYSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLKALFKALKRLKSLRDQFSFAENLYQIIGIDCFQKNDKKMFKSCRRLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IEE8-1", "uniprot_id": "SN12L_HUMAN", "id": "Q6IEE8-1", "name": "Schlafen family member 12-like", "aln": "-----------------------------------------------------MDLAR----------------------KEFLRGNGLAAGKMNISIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENKGYSYKKDGIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEALAADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQ--RITEILPQYVSAFANTDGGYLFVGLN-EDKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEP----VCEELPSPASTSSPVSQSYPLREYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMVQD-------------EEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTT-AQTMKDLEKALSNILPKENQIFLFVCLFRFCLFVCWF--------VCFFLR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :* :*:****** :*.:****:.*:.*** : *::: :.. :*:*:******** **.::*:.*.:.:**:* ** * :. :: : ::*** * :** :***. . : .* *:**.:.** * : : ::. *:::**. * . .. * : : :.* :*:* : :*.: **:: *.*:* ..* .* *:*** **:***:***:**:**: : :::***:** * * ** ::.* ::** *** *: .*:* ***: * . * *.:* ************* :*:****:.. * ::* ::*:: ::. . :. :: *: : : * :*. ::*: ::.*: **:*:.:: *::** **::: *: *.* *.*.. .*: * : *:*.* .* * **** * : .** :: : ** **. : . ** ::: ** .** : * * *** .: ", "identical_positions": 180, "similar_positions": 167, "identity": "26.01%" }, { "cls_id": "homologset.agr.RGD:620456", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48679-1", "uniprot_id": "LMNA_RAT", "id": "P48679-1", "name": "Prelamin-A/C", "aln": "-----------------------METPSQRRPTRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQSQGG---------------------GSVTKKRKLESSESR----SSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDD-PLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGTSLRTALINATGEEVAMRKLVRSLTMVEDNDDEEEDGDELLHHHRGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKA-ASGSGAQVGGSISSGSSASSVTVTRSFRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSSQNCSIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48678-1", "uniprot_id": "LMNA_MOUSE", "id": "P48678-1", "name": "Prelamin-A/C", "aln": "-----------------------METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQSQGG---------------------GSVTKKRKLESSESR----SSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIRRQNGDD-PLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGSSLRTALINSTGEEVAMRKLVRSLTMVEDNEDDDEDGEELLHHHRGSHCSGSGDPAEYNLRSRTVLCGTCGQPADKA-AGGAGAQVGGSISSGSSASSVTVTRSFRSVGGSGGGSFGDNLVTRSYLLGNSSPRSQSSQNCSIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02545-1", "uniprot_id": "LMNA_HUMAN", "id": "P02545-1", "name": "Prelamin-A/C", "aln": "-----------------------METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGG---------------------GSVTKKRKLESTESR----SSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDD-PLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVED--DEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08928-1", "uniprot_id": "LMNB_DROME", "id": "P08928-1", "name": "Lamin", "aln": "MSSKSRRAGTATPQPGNTSTPRPPSAGPQPPPPSTHSQTASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITP---ATNTATVQSFSQSLRNST-----RATPSRR---TP----SAAVKRKRAVVDESEDHSVADYYVSASAKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPSSLVMKS-QKWVSADNTRTILLNSEGEAVANLDRIK-----------------------------------------------------------------RIVSQHTSSSRLSRRRSVTAVDGNEQ------------LYHQQGDPQQSNEKCAIM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03427-1", "uniprot_id": "LMNA_DROME", "id": "Q03427-1", "name": "Lamin-C", "aln": "MSARR--------VTLNTRVSRASTSTPVGGASTSSRVGATSPTSPTRTSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRRTVIDESEDRTLSEYSVNAAAKGDLEIIEADVEGRFIKLHNKGTEEINLTGWQLTRIAGDE--ELAFKFSRGSKVLGGASVTIWSVDAGTAHDPPNNLVMK--KKWPVANSMRSVLANADKEDVASYDRVR-----------------------------------------------------------------ANVSSHTSRHRSSGTPSTGFTLGSG-----------------AGSTGVRSLFSLLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. : :::* **** :* ** :**.****** ****:*.**.**: * .: :.:.*.**.:.:* :* ** :*: **..*:::*: ::::.:: ** .:** : ** : .*: . : * *. : . : ::::.:: : :: : :*. : : :*:*: * * *** ** *:::*** *:.:::::*: *:: :: . ***. . :::::* ::***** *:* *:. :.*:: *. :::. : :* * :: : **:: * :**.*.*::.:*:. * :*::*:** * :*: : : * *: .:* .* :**.*** *:***::**:** ** *** *** **.: . . * . . .:..*::: **. :.: * :.* : : * * **:*::* **..*: : .**: * .:. :::* : . :*:*: .: ::*.**..** * :.* . . *: * *: * ** . :: :*. :* : * . *. . . ::", "identical_positions": 160, "similar_positions": 210, "identity": "22.38%" }, { "cls_id": "homologset.agr.RGD:620457", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91XS8-1", "uniprot_id": "ST17B_RAT", "id": "Q91XS8-1", "name": "Serine/threonine-protein kinase 17B", "aln": "MSRRRFDCRSISGLLTTTPQTP----MKTENFNNFYTLTPKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELARSCPHVINLHEVYETATEIILVLEYAAGGEIFNLCLPELAEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWLQQ---WDFGSLFHPEETSESSQ-----------------------------------------TQDLSLRSSEDKTPKS-CNGSCGDRE-----------------------------------------------------DKENIP--------------------EDDSLLSKRFRFDDSLPSPHELVPDLFC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG48-1", "uniprot_id": "ST17B_MOUSE", "id": "Q8BG48-1", "name": "Serine/threonine-protein kinase 17B", "aln": "MSRRRFDCRSVSGLLTTTPQTP----IKTENFNNFYTLTPKELGRGKFAVVRQCISKSTGQEYAAKSLKKRRRGQDCRAEILHEIAVLELARSCPHVINLHEVYENATEIILVLEYAAGGEIFNLCLPELAEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGNASELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSLLVKNPEKRPTAESCLSHSWLQQ---WDFGSLFHPEETSGSSQ-----------------------------------------IQDLTLRSSEEKTSKSSCNGSCGARE-----------------------------------------------------DKENIP--------------------EDGSLVSKRFRFDDSLPSPHELVPDLFC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94768-1", "uniprot_id": "ST17B_HUMAN", "id": "O94768-1", "name": "Serine/threonine-protein kinase 17B", "aln": "MSRRRFDCRSISGLLTTTPQIP----IKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQ---WDFENLFHPEETSSSSQ-----------------------------------------TQDHSVRSSEDKTSKSSCNGTCGDRE-----------------------------------------------------DKENIP--------------------EDSSMVSKRFRFDDSLPNPHELVSDLLC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KHT7-1", "uniprot_id": "DAPKR_DROME", "id": "Q0KHT7-1", "name": "Death-associated protein kinase related", "aln": "MFTEKGIFPIGDGLLDVDADRLKGLLVSCPDINEIYEVEQTPFARGKFAAVRRAIHKNTGSHFAAKFLKRRRRAQSSDKEIKHEIAVLMLCEGEDNIVNLNAVHETRSDTALLLELATGGELQ--TILDNEECLTEAQARHCMREVLKALKFLHDRSIAHLDLKPQNILLAGERIEDGLKLCDFGISRVVCEGINVREMAGTPDYVAPEVLQYEPLSLLTDIWSVGVLTYVLLSGFSPFGGDTKQETFLNISQCALTFPDNLFGGVSPVAIDFIRRALRIKPNDRMNATGCLDHIWLKDDCSLDRQIYLQPQSDAEEEEEEDVDDDVEDEEEEEQVEEEEEETQNVEEPTTEAPQQQQQPVQQHQLAKSGQIHSKPTHNGHHRANSGGSISKIPIATSKLQSTPSSETTTAIHTLTSNSNGHVHKPTQIVTPTRRASDSDKENTYTATFVKKPVATIQLGSSNGIEDATVVATLTLFPDAPTTPKVIRKTPTGESNGSATSVKALVKKFQLEDSSGSAVARRSGGAVTSSSGLHSPTTTSVRLNSIRRASEPLTTVYKKQTSQNGCSSTSNPSSSPGSSPTTSGSTATLLIHSQRLGNSTAPASHCVAVPATATATSSASSSNSSSGKSTSAAHHLHHHHMHHHHHHHHHHVVIAAKNAAAVAATNNLSLDQGIIC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: .*** . .: :. ::*::* : . :.*****.**:.* *.**..:*** **:***.*.. ** ****** *... .::**: *:*. :: *:** *:***: : : * ::* :. : ::::*:.: :**:..*.***********:. ..:*: ***:** : .. ::**: ***:*:***:*:*:*:: **:*.:*:::*:**: *** *: :***:***** : :.:: *..** :* ***: * :*:.* .* **.* **:: * ::*:. : ..: *: : .* : .*. ** .. **** ** ::::. * *: ..*: : ", "identical_positions": 132, "similar_positions": 133, "identity": "19.53%" }, { "cls_id": "homologset.agr.RGD:620458", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35188-1", "uniprot_id": "X3CL1_MOUSE", "id": "O35188-1", "name": "Fractalkine", "aln": "MAPSPLAWLLRLAAFFHLCTLLPGQHLGMTKCEIMCDKMTSRIPVALLIRYQLNQESCGKRAIVLETTQHRRFCADPKEKWVQDAMKHLDHQAAALTKNGGKFEKRVDNVTPGITLATRGLSPSALTKPESATLEDLALELTTISQEARGTMGTSQEPPAAVTGSSLSTSEAQDAGLTAKPQSIGSFEAADISTT-VWPSPAVYQSGSSSWAEEKATESPSTTAPSPQVSTTSPSTPEENVGSEGQPPWVQGQDLSPEKSLGSEEIN--PVHTDNFQERGPGNTVHPSVAPISSEETPSPELVASGSQAPKIEEPIHATADPQKLSVLITPVPDTQAATRRQAVGLLAFLGLLFCLGVAMFAYQSLQGCPRKMAGEMVEGLRYVPRSCGSNSYVLVPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55145-1", "uniprot_id": "X3CL1_RAT", "id": "O55145-1", "name": "Fractalkine", "aln": "MAPSQLAWLLRLAAFFHLCTLLAGQHLGMTKCNITCHKMTSPIPVTLLIHYQLNQESCGKRAIILETRQHRHFCADPKEKWVQDAMKHLDHQTAALTRNGGKFEKRVDNVTPRITSATRGLSPTALAKPESATVEDLTLEPTAISQEARRPMGTSQEPPAAVTGSSPSTSKAQDAGLAAKPQSTGISEVAAVSTT-IWPSSAVYQSGSSLWAEEKATESPPTIALSTQASTTS--SPKQNVGSEGQPPWVQEQDSTPEKSPGPEETN--PVHTDIFQDRGPGSTVHPSVAPTSSEKTPSPELVASGSQAPKVEEPIHATADPQKLSVFITPVPDSQAATRRQAVGLLAFLGLLFCLGVAMFAYQSLQGCPRKMAGEMVEGLRYVPRSCGSNSYVLVPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78423-1", "uniprot_id": "X3CL1_HUMAN", "id": "P78423-1", "name": "Fractalkine", "aln": "MAPISLSWLLRLATFCHLTVLLAGQHHGVTKCNITCSKMTSKIPVALLIHYQQNQASCGKRAIILETRQHRLFCADPKEQWVKDAMQHLDRQAAALTRNGGTFEKQIGEVKPRTTPAAGGMDESVVLEPE-ATGESSSLEPTPSSQEAQRALGTSPELPTGVTGSSGTRLPPTPKAQDGGPVGTELFRVPPVSTAATWQSSAPHQPGPSLWAEAKTSEAPSTQDPSTQASTASSPAPEENAPSEGQRVWGQGQSPRPENSLEREEMGPVPAHTDAFQDWGPGSMAHVSVVPVSSEGTPSREPVASGSWTPKAEEPIHATMDPQRLGVLITPVPDAQAATRRQAVGLLAFLGLLFCLGVAMFTYQSLQGCPRKMAGEMAEGLRYIPRSCGSNSYVLVPV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *:******:* ** .**.*** *:***:* * **** ***:***:** ** *******:*** *** *******:**:***:***:*:****:***.***::.:*.* * *: *:. :.: :** ** *. :** *. ****: .:*** * *:.***** : . . . * . ... :**: * *.* :*.*.* *** *::*:*.* *.*.**:* :*::*. **** * * *. **:* ** . *.*** **: ***. .* **.* *** *** * ***** :** ******* ***:*.*:******:**************************:***************.*****:**************", "identical_positions": 244, "similar_positions": 77, "identity": "61.31%" }, { "cls_id": "homologset.agr.RGD:62046", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49744-1", "uniprot_id": "TSP4_RAT", "id": "P49744-1", "name": "Thrombospondin-4", "aln": "MTMITPSSKLTLTKGNKSWSSTRCGAFLLLHLVLQPWQRAGAQATPQVFDLLPSSSQRLNPAALQP-VLTDPTLHELYVIS--------TFKLQSKSSATIFGLYSS-SDNSKYFEFTVMGRLNKAILRYLKDDGKIHLVVFNNLQLADGRRHRILLRLSNLQRGAGS-------------VELYLDCVQVDSVNNLPRAFSGLTQNPQAIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLA----ATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGP-------------LSFQSPTPNTLVPIAPPAPP---------------TRPTRRCDSSPCFRGVRCTDTRDGFQCGPCPDGYTG------------------------------------------NGITCSDVDECK-YHPCYPGVRCTNLAPGFRCDACPVGFTGPMVQGVGINFAKTN--KQVCTDVDECR---NGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCRT-ERSCRNPEQNPCSVHAQCIEERQGDVTCVCGVGWAGRAGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNTDKDIFGDACDNCRGVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGMPDLFPPGPDNCRLVPNPAQEDSNNDGVGDICEADFDQDKVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP----EDFQEFQIQT-FDRLDN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1T2-1", "uniprot_id": "TSP4_MOUSE", "id": "Q9Z1T2-1", "name": "Thrombospondin-4", "aln": "--MPAPR--------------AAAAAFLLLHLVLQPWQRTSAQATPQVFDLLPSSSQRLNPSALQP-VLTDPTLHEVYLIS--------TFKLQSKSSATIFGLYSS-SDNSKYFEFTVMGRLNKAILRYLKNDGKIHLVVFNNLQLADGRRHRVLLRLSNLQRGDGS-------------VELYLDCAQADSVRNLPRAFSGLTQNPESIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLA----ATSTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGP-------------LSFQSPTPNTLVPIAPPAPP---------------TRPTRHCDSSPCFRGVRCTDTRDGFQCGPCPDGYTG------------------------------------------NGITCSDVDECK-YHPCYPGVRCVNLAPGFRCDACPVGFTGPMVQGVGINFAKTN--KQVCTDVDECQ---NGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCKT-ERSCRNPEQNPCSVHAQCIEERQGDVTCVCGVGWAG-DGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNIDQRNSDKDIFGDACDNCRMVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDDVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNNDGVGDICEADFDQDQVIDHIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP----EDFQEFQTQS-FDRLDN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35443-1", "uniprot_id": "TSP4_HUMAN", "id": "P35443-1", "name": "Thrombospondin-4", "aln": "--MLAPR----------------GAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLP-VLTDPALNDLYVIS--------TFKLQTKSSATIFGLYSS-TDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLADGRRHRILLRLSNLQRGAGS-------------LELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLA----ATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGP-------------LKFQSPTPSTVVPPAPPAPP---------------TRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTG------------------------------------------NGITCIDVDECK-YHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSN--KQVCTDIDECR---NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA-ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG-DGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP----EDFQEFQTQN-FDRFDN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JGW0-1", "uniprot_id": "TSP4B_DANRE", "id": "Q8JGW0-1", "name": "Thrombospondin-4-B", "aln": "----------------------MAGTMHLLTAVSLILMLSSANAESTVYNLLTSP--DCLPDLLHG-GLAEQGVTELYILT--------TFRIQPGTGNTIFSLYNP-RDNSKYFEFSVFGKANKAILRYLRRDGRMSAVTFNKLNLADGEKHRLLFHLKGLEVGHPGGFPHSQGALPVPGVELHLDCRLVETLRDLPAVFNGLN-NHQAVELKTMQGKAQEGLEELKLAYGDSVENVASLQDCHTQ-SDSVQ----ALGLN--TKQLTTQMLELTKVINELKDVLIQQVKETSFLRNTISECQACG----------------------------LSGAEV---------------VKP--KCAPGVCFRDDMCIETAEGVECGPCPDGYTG------------------------------------------DGYSCDDVDECQ-FNPCFPGVRCVNMAPGFRCEACPLGFTGKPLEGVGVAYAQTH--KQVCDDIDECKGPDNGGCTANSICVNSVGSYQCGRCKTGFTGDQIRGCKP-EKSCGNRLQNPCDPNAQCTEERDGTITCQCGIGWAG-NGYLCGKDTDIDGYPDERLRCRDPTCRKDNCVTVPNSGQEDADGDGKGDACDPDADGDGILNEQDNCWLTPNINQQNSDKDSHGDACDNCVRVDNPDQRDTDSDGLGDACDDDMDGDGLKNFLDNCQRVKNRDQLDRDGDGVGDACDSCPDIPNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSKDNCPMVINSSQLDTDKDGIGDECDDDDDNDGIPDSLPPGPDNCRLVPNPEQIDDNNDGVGDICESDFDQDKVIDRIDNCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYLQHRPQVGYIRVRFYEGTELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP----EDFQEFSTQHGMDPL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM97-1", "uniprot_id": "Q9VM97_DROME", "id": "Q9VM97-1", "name": "", "aln": "--MNWTR------------VLLIGLTALALTFVDVASLSLDPVASAELEQFIRKGDVVISTRHIRPRRKLHISIEALFMIDFPMLKHKMSFFLDRKQQRVTLDISANGATESRNFEIPNIN--ETSTIRSLALQFSKNRITLH-VDCKASTHHDIDMNLAKLYTQMDDPVIKLFRE---RKYPLHFDGDMEHSLQRANCQKGNHRRGNRRMLRNKITEREKNKKRDVRGWYEPTIAREGVVDHRHQEVPTDVERGDIPVLNGDCEDALARSLSDLLALVKLLREDVAHQRQEIAYLRMLLENCAGCKNPLTTDNQLRIEPDCRSANPCYPGVECLDSAAGPRCGHCPLGFIGDGKSCKPGVTCAHHMCYPGVQCHDTVNGAQCDSCPAGYEGDGRTCSLRNPCLDTPCPSGAQCLQVGYPPYFHCISCPMGHEVNGTSCRDMNECLLYDPCDELATCTNLSPGFQCSPCPVGFDGTHAHGYFADYYSVDYRRQTCLDVDECRTG-FFRCPEHSTCINEIGSYRC-QCHEGYVTNGTYSCLDRSSVFMCPDGTVCDRNAVCLRMDNIRHKCHCNVGWAG-NGLICGRDTDVDGWPDQAIGCPELRCQRDNCPKLPNSGQEDADLDGHGDGCDDDADGDNVQNSQDNCWLAYNTEQLDSDGDKVGDVCDNCVLKYNPRQLDTDEDGLGDECDGDIDNDSIPNALDNCPLLPNPSQSDVDNDGVGDACDNCPNLPNPDQKDRDMDFVGDACHRDIDGDDDGVPNSLDNCPMVSNSDQLDTDGDGTGDECDDDMDGDGIPNYK----DNCPLAKNPKQDDFNRNGKGDSCEDDEDVDGVPNGMDNCPNNSMIHHTDFRTLQTIPLDPKGLSQADPNWVVHANGTEIVQTLNSDPGLAVGKDAFGGVDFDGTFYINDDTDDDYAGFVFSYQSSYKYYVVQWKKGTQTYWEPRPFTASAAPGIQIKLVNSTEGPGPMMRNSLWHEGNTDGEARLLWKDPKNIAWKERTSYRWSLVHRPAIGLIRLQMHEGNRLIFDSGNVFDSTLKGGRLGVFCFSQRMIIWSNLQYKCNNRVKPLIYNDLSDYLKTK-VELQD-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * .. * . : ::: . . : . : :::: :* :: . :.: :*: **:. :. :.: :* * : :.:: :: . :* : :.* * . *::* .::. . . : ..: : :: .::: :: . . ::. . : . : . . : .: :* :: ::: : :* :* ::** : :* .* . * :* * *: . * :: :* :*..** ** * :* :* *::** :.** . * *::***:*..**:** * .* : . . :*.* *:***: * :* *:* :***:* *: *:. : .* . . *. :* * . : .* *.:**** * :**:*.*:*.:**: : * *::*** :********* ** **.** *****.: *.**** * * :* ::* * **.**** * * *** ** ** **.*:*.*.: * **** . * .* * *.*.******.**::.**:*.* * *:***:*. : *.*.** :* **** * ** ***** ** ******* *.**:*: *** *. ** * * * :* ** ** * * * * : :* **:*: : ****: **: ***:* :* ****** :* *****:********* **.****:***::* ********:*.**.* .:*** **: ****:. ** * * ****:* *:*. *** :****** *:*..:.******.:*:.**::.**** * *** :* **::::**..*: *** .:*:*::***********. ******:*:**: : :*:.:: .: ", "identical_positions": 355, "similar_positions": 255, "identity": "32.6%" }, { "cls_id": "homologset.agr.RGD:620460", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R044-1", "uniprot_id": "NPHN_RAT", "id": "Q9R044-1", "name": "Adhesion molecule nephrin", "aln": "--------------------------MGAKRVTVRGARTSPIHRMSSLTPLLLMGMLTSGLAESPVPTSAPRGFWALSENLTAVEGTTVKLWCGVRAPGSVVQWAKDGLLLGPNPKMPGFPRYSLEGDRAKGEFHLLIEACDLSDDAEYECQVGRSELGPELVSPKVILSILVSPKVLLLTPEAGSTVTWVAGQEYVVTCVSGDAKPAPDITFIQSGRTILDVS-SNVNEGSEEKLCITEAEARVIPQSSDNGQLLVCEGSNPAL--DTPIKASFTMNILFPPGPPVIDWPGLNEGHVRAGENLELPCTARGGNPPATLQWLKNGKPVSTAWGTEHAQAVAHSVLVMTVRPEDHGARLSCQSYNSVSAGTQERSITLQVTFPPSAITILGSVSQSENKNVTLCCLTKSSRPRVLLRWWLGGRQLLPTDETVMDGLHGGHISMSNLTFLVRREDNGLPLTCEAFSDAFSKETFKKSLTLNVKYPAQKLWIEGPPEGQYIRTGTRVRLVCLAIGGNPDPSLIWFKDSRPVSEPRQPQEPRRVQLGSVEKSGSTFSRELVLIIGPPDNRAKFSCKAG------QLSASTQLVVQFPPTNLTILANSSALRPGDALNLTCVSISSNPPVNLSWDKEGERLEDVAAKPQSAPFKGSAASRSVFLRVSSRDHGQRVTCRAHSEALRETVSSFYRFNVLYPPEFLGEQVRAVTVVEQGQVLLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSGG-ALQLWNVTRADDGFYQLHCQNSEGTAEALLKLDVHYAPTIRALRDPTEVNVGGSVDIVCTVDANPILPEMFSWERLGEEEEDLNLDDMEKVSKGSTGRLRIRQAKLSQAGAYQCIVDNGVAPAARGLVRLVVRFAPQVDQPTPLTKVAAAGDSTSSATLHCRARGVPNIDFTWTKNGVPLDLQDP-RYTEHRYHQGVVHSSLLTIANVSAAQDYALFKCTATNALGSDHTNIQLVSISRPDPPLGLKVVSISPHSVGLEWKPGFDGGLPQRFQIRYEALETPGFLHVDVLPTQATTFTLTGLKPSTRYRIWLLASNALGDSGLTDKGIQVSVTTPGPDQAPE--------------------------------------------------------DTDHQLPTELPPGPPRLPLLPVLFAVGGLLLLSNASCVGGLLWRRRLRRLAEEISEKTEAGSE-DRIRNEYEESQWTGDRDTRSSTVSTAEVDP----NYYSMRDFSPQLPPTLEEVLYHQ---GAEGEDMAFPGHLHDEVERAYGPPGAWGPLYDEVRMDPYDLRWPEVQCEDP----------------------------------------------------RGIYDQVAADMDAVEASSLP---------------------------------FELRGHLV-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZS7-1", "uniprot_id": "NPHN_MOUSE", "id": "Q9QZS7-1", "name": "Nephrin", "aln": "--------------------------MGAKEATVRGPGASPVHRTCHLIPLLLAGMLTTGLAQSPVPTSAPRGFWALSENLTVVEGSTVKLWCGVRAPGSVVQWAKDGLLLGPNPKIPGFPRYSLEGDSAKGEFHLLIEACDLSDDAEYECQVGRSELGPELVSPSVILSILVSPKVLQLTPEAGSTVTWVAGQEYVVTCVSGDAKPAPDIIFIQGGRTVEDVS-SSVNEGSEEKLFFTEAEARVTPQSSDNGQLLVCEGSNPAL--ATPIKASFTMNILFPPGPPVIDWPGLNEGHVRAGENLELPCIARGGNPPATLQWLKNGKPVSIAWGTEHAQAVAHSVLVMTVRPEDHGARLSCQSYNSVSAETQERSITLQVTFPPSAVTILGSTSQSENKNVTLCCLTKSSRPRVLLRWWLGGRQLLPTDETVMDGLHGGHISMSNLTLLVKREDNGLSLTCEAFSDAFSKETFKKSLTLNVKYPAQKLWIEGPPEGQSIRTGTRVRLVCLAIGGNPEPSLTWLKDSRPVNDPRQSQEPRRVQLGSVEKSGSTFSRELVLIIGPPDNLAKFSCKAG------QLSASTQLVVQFPPTNLTILANSSALRPGDALNLTCVSISSNPPVNLSLDKEGERLDDVAAKPQSAPFKGSAASRSVFLRVSSRDHGHRVTCRAHSEALRETVSSFYRLNVLYPPEFLGEQVRAVTVVEQGQALLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSGG-ALQLWNVTRADDGFYQLHCQNSEGTAEALLKLDVHYAPTIRALKDPTEVNVGGSVDIVCTVDANPILPEMFSWERLGEDEEELNLDDMEKMSKGSTGRLRIRQAKLSQAGAYQCIVDNGVAPAARGLVRLVVRFAPQVDHPTPLTKVAAAGDSTSSATLHCRARGVPNIDFTWTKNGVPLDLQDP-RYTEHKYHQGVVHSSLLTIANVSAAQDYALFKCTATNALGSDHTNIQLVSISRPDPPLGLKVVSVSPHSVGLEWKPGFDGGLPQRFQIRYEALESPGFLYMDVLPAQATTFTLTGLKPSTRYRIWLLASNALGDSGLTDKGIQVSITTPGLDQAPE--------------------------------------------------------DTDQPLPTEQPPGPPRLPLLPVLFAVGGLLLLSNASCVGGLLWRRRLRRLAEEISEKTEAGSEEDRIRNEYEESQWTGDRDTRSSTVSTAEVDP----HYYSMRDFSPQLPPTLEEVSYRQAFTGIEDEDMAFPGHLYDEVERVYGPPGVWGPLYDEVQMDPYDLRWPEVKYEDP----------------------------------------------------RGIYDQVAADMDAGEPGSLP---------------------------------FELRGHLV-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60500-1", "uniprot_id": "NPHN_HUMAN", "id": "O60500-1", "name": "Nephrin", "aln": "---------------------------MALGTTLRAS-------------LLLLGLLTEGLAQLAIPASVPRGFWALPENLTVVEGASVELRCGVSTPGSAVQWAKDGLLLGPDPRIPGFPRYRLEGDPARGEFHLHIEACDLSDDAEYECQVGRSEMGPELVSPRVILSILVPPKLLLLTPEAGTMVTWVAGQEYVVNCVSGDAKPAPDITILLSGQTISDIS-ANVNEGSQQKLFTVEATARVTPRSSDNRQLLVCEASSPAL--EAPIKASFTVNVLFPPGPPVIEWPGLDEGHVRAGQSLELPCVARGGNPLATLQWLKNGQPVSTAWGTEHTQAVARSVLVMTVRPEDHGAQLSCEAHNSVSAGTQEHGITLQVTFPPSAIIILGSASQTENKNVTLSCVSKSSRPRVLLRWWLGWRQLLPMEETVMDGLHGGHISMSNLTFLARREDNGLTLTCEAFSEAFTKETFKKSLILNVKYPAQKLWIEGPPEGQKLRAGTRVRLVCLAIGGNPEPSLMWYKDSRTVTESRLPQESRRVHLGSVEKSGSTFSRELVLVTGPSDNQAKFTCKAG------QLSASTQLAVQFPPTNVTILANASALRPGDALNLTCVSVSSNPPVNLSWDKEGERLEGVAAPPRRAPFKGSAAARSVLLQVSSRDHGQRVTCRAHSAELRETVSSFYRLNVLYRPEFLGEQVLVVTAVEQGEALLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSSG-ALHLWNVTRADDGLYQLHCQNSEGTAEARLRLDVHYAPTIRALQDPTEVNVGGSVDIVCTVDANPILPGMFNWERLGEDEEDQSLDDMEKISRGPTGRLRIHHAKLAQAGAYQCIVDNGVAPPARRLLRLVVRFAPQVEHPTPLTKVAAAGDSTSSATLHCRARGVPNIVFTWTKNGVPLDLQDP-RYTEHTYHQGGVHSSLLTIANVSAAQDYALFTCTATNALGSDQTNIQLVSISRPDPPSGLKVVSLTPHSVGLEWKPGFDGGLPQRFCIRYEALGTPGFHYVDVVPPQATTFTLTGLQPSTRYRVWLLASNALGDSGLADKGTQLPITTPGLHQPSG--------------------------------------------------------EPEDQLPTEPPSGPSGLPLLPVLFALGGLLLLSNASCVGGVLWQRRLRRLAEGISEKTEAGSEEDRVRNEYEESQWTGERDTQSSTVSTTEAEP----YYRSLRDFSPQLPPTQEEVSYSRG-FTGEDEDMAFPGHLYDEVERTYPPSGAWGPLYDEVQMGPWDLHWPEDTYQDP----------------------------------------------------RGIYDQVAGDLDTLEPDSLP---------------------------------FELRGHLV-----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E9F2-1", "uniprot_id": "Q0E9F2_DROME", "id": "Q0E9F2-1", "name": "", "aln": "MALQQQHQRHQQHQQHQQQQQQQQQQQHIKWQQHATKRRRCRQHWIKHLQLLRLLAVIVLASAPVPSHAQQQKFRTTPHDLQVLEGAEAMMRCEVANVAGAVQWTKDGFALGFSAVIPGFPRYSVLGDRKQGIYNLRISNASINDDADYQCQVGPARLNSAIRANAKLTVISPPASIEIKGYSHNSKVEVRENQDLQLKCIVANAKPAAQIVWYRGNVEYKPEKREDTVEESTAKRFTTTSSLKLKPGPDDDYTEYTCQARHKALSPDMPMRATVQLSVLYPPGPPYIEGYSAGE-TLRRGQTVELMCRSRGGNPPAQLIWYKNGSQIRMAY--RTSGRLSENIYTFTAEAGDNKARFRCEASNVMSQNPLKAEVELSVLFAPTHVTVMGPTEARVGDIVPLTCTTAPSNPPAEIKWMVGGRQVRNATSKTIVSPEGGWTTTSNITAVVEPNKRSLVVICHGLNMQLTENVVS-THTINVLYPPAPPLISGYMEGQIIPAGSVQKLLCVSSGGNPLATLTWYKNDKRIN-------------SVIRAADKSVSAEITILANVSDNQAQYRCEASNSATEIPLFQSTTLSVHFAPETVKIRIEPEELRPGMEATIICDSSSSNPPAKLSWWKDGIPIEGINNTSKPGLWGGTVSTLEFRVNVTQEMNGQVYTCQSANEALQRSAHEAVSLDVLYRPKFVPPPSSTAVGVEGESLQVSLQTRANPTPVTYKWTKDGTTIPQD--GDHRIFADGGSLNFTRLHRDDAGIYSCSASNSQGGATLNITVVVEYGTTIKSVSENIVVNPGEDAMLSCTVEGKPLTEEHVKWERVGYDMTVKTSTTFANG----TSYLHIKDAKREDVGNFRCVADNRVDNPTNRDILLIVKFAPEIAKTPTLLRAASG--TGERGRLPCRAQGSPKPQFIWRQDKKDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAYECVARNELGEAVETVRLEITSQPDPPLSLNILNVTHDTVTLAWTPGFDGGLKASYRVRYRMADREQYKYIDGLP-NSHKLTIGGLRMNTLYLFSVMSWNELGQSSYLPDLARAETKEAPPPSHPASSLGGGPPTTSQTPLGGTSGMLLVGVGAGIVVVLLNVFVIGCCLHKRNEKRLKRGLELMPAELTEDSSNTPNLVIIGISLAAFGFLLVN-ASLVAWFFVHQRRKKVAETTNQPAKTATIEMYAPSSYNDTVTGETLSSVSEKSESYSNEGSSQPEYIDEVRKKAASTYLVEGSDMPPPRYQKDGTLPVIYPNNVVNACTLPHPRHNNGSAAIHMTRDDQMLISKGVYIPSPSPAPPPDGSYYNMNSDRYLSYPPMEYPAALDFTAQPMPMAHLQPMTVTSLATNGGPTLIGNGSVAAVAGGSGTLRRGILRGVVGVPQPDVTHHTSTVGGSPMQMLHDLHPVNLSASTLTTSTTLNGSLPTATATLPRQPHGILKDPNRNKQQQQQQQQQQQQQQLQHQQQLLNASLVGVGVPVSAPLGSLQILNLPPASGGLGNNLLMTTNAFDPTTVGLSSFGAVSQAGGIPVAYTDADGHLV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z9X4-1", "uniprot_id": "A1Z9X4_DROME", "id": "A1Z9X4-1", "name": "", "aln": "----------------------MQFWITLTFAVHLATT-----------ICHVMAAVTAPTPAAQVAAPPVQKFHLTPHDLQILEGTDTLLRCEVSNRAGKVQWTKDGFALGFSAVIPGFPRYSVLVDAKQNAYNLQIKNATLEDDAEYQCQVGPAAGNPAIRANAKLSIVAAPSSIVIEGYARNARVEVEERQNLTLHCIAENANPAAEIVWFQGEVPVSTAP-IVTVNQTAPKRFTTSSTLHLQPRAEDDYKEFSCEARHKALPPDVPMRAQVQLSVLYPPGAPFFEGYSQGE-TLHRGQEVQIACRSRGGNPPAQLTWYRNGVAISSPQ--RTSGRLSENVYKFTAAAEDNGANLVCEAKNLLATTPLRAELNLTVLYAPKDVYLSGANQAKVGDSVQLSCVTAPSNPQARISWSINGRPLDNSTYKTTSSSDGGWVSSSNISLTIDSQSRTFIAVCHALNTELTQNVVG-SHTVNVLYPPSPPLLTGYNDGDILISGSILKLQCSSAGGNPPPTLQWYKNDKIIN-------------APSKLVDSKITSELSLLVNASDNNAIYKCKVQNAAIDIPLFATKTLGVHFPPETVKISVVPKNLVPGIRAKLICDSSSSNPPAKISWWKDGIPVEGLNLANRPGLWGGSVSTLEMYVNITQDLDGIVYTCQSHNEVLQRSVHETISLDILYPPKFETPQSTTFVGVEGAPFHVELLASGNPMVITYTWTKDGLPISSNSLSGQRLISDGPRLNISRLSRNDAGVYICEALNSQGTALLEIQVAVEYAPTITAVSEGRSFVAGEPAVLACHIQARPLEAAHVRWSRDGYDLATRTISSFENG----TALLQIASVERSDIGNFTCIVDNQRGAPAAQNVLLVVQTAPEIDHSPGFTRYAAR--LGVRAQLICRSLASPQPSFIWRRHGKDLKMQRRNKFKSVERQVDALNFESALLIENTSPDDYGQYECVVRNSLGQASTTLEFSKPSRPDAPLQLRVGNVSDTGVDLNWTPGFDGGMQTYFRLRLKQHGEDKYKYVDAKP-GHQNISLDGLKPGATYYFSVMAANEAGGSKFMPDIKLTLSKGSQPHS---------------------------------------------------------------AEYTE-KDELPNVMIIGITSAAMVLLVLN-AALVAWFVIRRQNKSQSE-----AEPSNDDVYSKDDS-QSVYKLPITALQADVQKKAAASTYLVENVDIIQSTAYPPKYQESSMCTPPYPLCNPDFTRTLPNPKRHSQRNSATGMIEG--MQMRSKDDHMLISNGLYIPSPSPAS--------------------------------------------SLVIKG--SYISSPSPAPPADGS---------------------------------YFNMSDKYMSYPPVTY----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : * ..:* :**: . : * * .. ***:***: ** .. :****** : * :. ::* *. . :.***:*:**** : .. : : : : ...: .: * *: : *: :*:**.:* . . : : * . : :: * ..*: *:. ** *::* . :.:*:***.* :: . .* :: *: ::: * :***** * * * :** : . . : ::..: :*. . *: *.: *:: * :: . . : * * :.*. : : *. . .. * * * : .*.* . : * :. * : .. . .** : **:: :.. : *..:. ::::.. : :** **. : * :*: : :*: :* * : **** .:* * *:.: :. . . ....: *: :: . .** * : *:. * :. * *:*.* .:.* .. * ** .: * * *****.::* *:* ::.: : . : *:.:: .. :.::. .* **:: . *:.:. . :::** *:* . . ** : : . .** ::.** * :. :*:::.* *:: .: * * *.* . **:* * : : *.*..** :: : . * . : * ::..*: . *.* * : . : : *. *:* .: : * : *:.** .: : *:*: **:: :.. : : *: . * **: . *: * * :. * :: :: : . : . : : :. **. : *.. * **. .:.: *:**.* *.: .:: * * *.******: : :* . : ::* * .::: **: .: * . ::: * * * . . . . ** . : :: : * :*::. *: *. .. ::: : :* ::... .. :: : . .. . .. . * : : . . * . * .* .* :. : ... .:: : ", "identical_positions": 222, "similar_positions": 397, "identity": "14.15%" }, { "cls_id": "homologset.agr.RGD:620461", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91X05-1", "uniprot_id": "PODO_MOUSE", "id": "Q91X05-1", "name": "Podocin", "aln": "MDSRARSSSREAHGRSSRSSSRDDKKAKAGRGSRGRARPDAGAERQSTGRTATRGEPRAPAATATVVDVDEVRGPGEEGTEVVALLESERPEEGIKPSGLGACEWLLVLASLIFIIMTFPFSIWFCIKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEVVTKDMFIMEIDAVCYYRMENASLLLSSLAHVSKAIQFLVQTTMKRLLAHRSLTEILLERKSIAQDVKVALDAVTCIWGIKVERTEIKDVRLPAGLQHSLAVEAEAQRQAKVRVIAAEGEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPATVVLPLPFDMLSLLSSPGNRAQGSINYPSSSKPVEPLNPKKKDSPML", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K4G9-1", "uniprot_id": "PODO_RAT", "id": "Q8K4G9-1", "name": "Podocin", "aln": "MDSRARSSSRKTHGRGSRSSSRDDKKSKAGRGNRGRARPDAGAERQSAGRTGTREEHRAPAAT--VVNVDEVRSPGEEGTEVVALLESERPEEGIKPSGLGACEWLLVLSSLIFIIVTFPFSIWFCIKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEVVTKDMFIMEIDAVCYYRMENASLLLSSLAHVSKAIQFLVQTTMKRLLAHRSLTEILLERKSIAQDVKVALDSVTCVWGIKVERTEIKDVRLPAGLQHSLAVEAEAQRQAKVRVIAAEGEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTDKPSTVVLPLPFDMLNLLSSPSNRAQGSINYPSSPKPVEPLNPKRKDSPML", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NP85-1", "uniprot_id": "PODO_HUMAN", "id": "Q9NP85-1", "name": "Podocin", "aln": "MERRARSSSRESRGRGGRTPHKENKRAKAERSGGGRGRQEAGPEPSGSGRAGTPGEPRAPAAT--VVDVDEVRGSGEEGTEVVALLESERPEEGTKSSGLGACEWLLVLISLLFIIMTFPFSIWFCVKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEIVTKDMFIMEIDAICYYRMENASLLLSSLAHVSKAVQFLVQTTMKRLLAHRSLTEILLERKSIAQDAKVALDSVTCIWGIKVERIEIKDVRLPAGLQHSLAVEAEAQRQAKVRMIAAEAEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPSTVVLPLPFDLLNCLSSPSNRTQGSLPFPSPSKPVEPLNPKKKDSPML", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *******:::**..*:. :::*::** *.. **.* :**.* ..:**:.* * ****** **:*****..******************* *.************ **:***:*********:*****************************************************:************:*********************:******************************.*****:***:******* ****************************:****.***********************************:**:*********:*. ****.**:***: :**..*********:******", "identical_positions": 320, "similar_positions": 49, "identity": "83.12%" }, { "cls_id": "homologset.agr.RGD:620462", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58750-1", "uniprot_id": "PIM3_MOUSE", "id": "P58750-1", "name": "Serine/threonine-protein kinase pim-3", "aln": "MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKVYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGVAVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHNCGVVHRDIKDENLLVDLRSGELKLIDFGSGAVLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLFFRRRVSPECQQLIEWCLSLRPSERPSLDQIAAHPWMLGTEGSVPENCDLRLCALDTDDGASTTSSSESL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70444-1", "uniprot_id": "PIM3_RAT", "id": "O70444-1", "name": "Serine/threonine-protein kinase pim-3", "aln": "MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKVYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGMAVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHNCGVVHRDIKDENLLVDLRSGELKLIDFGSGAVLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLFFRRRVSPECQQLIEWCLSLRPSERPSLDQIAAHPWMLGTEGSVPENCDLRLCALDTDDGASTTSSSESL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86V86-1", "uniprot_id": "PIM3_HUMAN", "id": "Q86V86-1", "name": "Serine/threonine-protein kinase pim-3", "aln": "MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGVPESCDLRLCTLDPDDVASTTSSSESL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************************************.********************************************* :****************************************************************************.*******************************:*************************************************************:*************.************************::*.***.******:**.** **********", "identical_positions": 312, "similar_positions": 12, "identity": "95.71%" }, { "cls_id": "homologset.agr.RGD:620463", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPF2-1", "uniprot_id": "MUC18_RAT", "id": "Q9EPF2-1", "name": "Cell surface glycoprotein MUC18", "aln": "--------MGLPRLVCAFLFAACCCCRSATGVPGEEKQPTPTPDPVEVEVGNTALLKCGPAHPSGNFSQVEWFLIHKE---RQIPIFRVHQGKGQSEPGEYEHRLSLHGP--------GATLALSQVTPHDDRMFLCKSK--QPRPQDHYVQLQVYKAPEEPTIQANVLGIHVDIQELKEVATCVGRNGYPIPQVIWYKNGRPLQEEENRVHIQSSQTVESSGLYTLKSVLSARLVKEDKDAQFYCELSYRLPSGNRMKESKEVTVPVLYPAEKVWVEVEPVG-LLKEGDHVKIRCLTDGNPQPHFTINKKNPSTEEMEEESTDENGLLSLEPAQKHHSGVYQCQSLDLETTVM-LSSDPLELLVNYVSDVQVDPTAPEVQE-GDSLTLTCKAESNQDLEFEWLRDKTGQLLGKGPILQLNNVKREAGGRYLCVASVPSVPGLNRTRRVSVGIFGSPWMAAKER--KVWAQENAMLNLSCEASGHPQPTISWNINGSATEWNPDPQTVVS------TLNVLVTPELLETGAECTASNSLGSNTTVIILKLVTLTTLTPDSSQTTGLSTPTVSPHSRANSTSTEKKLPQQESKGVVIVAVIVCTLVLAVLGATLYYFYKKGKLPCGRSGKQEIT-----LPPTRKSEFVVEVKSDKLPEEMALLQGSNGDKRAPGDQGEKYIDLRH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2Y2-1", "uniprot_id": "MUC18_MOUSE", "id": "Q8R2Y2-1", "name": "Cell surface glycoprotein MUC18", "aln": "--------MGLPKLVCVFLFAACCCCRRAAGVPGEEKQPVPTPDLVEAEVGSTALLKCGPSRASGNFSQVDWFLIHKE---RQILIFRVHQGKGQREPGEYEHRLSLQDS--------VATLALSHVTPHDERMFLCKSK--RPRLQDHYVELQVFKAPEEPTIQANVVGIHVDRQELREVATCVGRNGYPIPQVLWYKNSLPLQEEENRVHIQSSQIVESSGLYTLKSVLSARLVKEDKDAQFYCELSYRLPSGNHMKESKEVTVPVFYPAEKVWVEVEPVG-LLKEGDHVTIRCLTDGNPQPHFTINKKDPSTGEMEEESTDENGLLSLEPAEKHHSGLYQCQSLDLETTIT-LSSDPLELLVNYVSDVQVNPTAPEVQE-GESLTLTCEAESNQDLEFEWLRDKTGQLLGKGPVLQLNNVRREAGGRYLCMASVPRVPGLNRTQLVSVGIFGSPWMALKER--KVWVQENAVLNLSCEASGHPQPTISWNVNGSATEWNPDPQTVVS------TLNVLVTPELLETGAECTASNSLGSNTTTIVLKLVTLTTLIPDSSQTTGLSTLTVSPHTRANSTSTEKKLPQPESKGVVIVAVIVCTLVLAVLGAALYFFYKKGKLPCGRSGKQEIT-----LPPTRKSEFVVEVKSDKLPEEMALLQGSNGDKRAPGDQGEKYIDLRH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43121-1", "uniprot_id": "MUC18_HUMAN", "id": "P43121-1", "name": "Cell surface glycoprotein MUC18", "aln": "--------MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAP--ELVEVEVGSTALLKCGLSQSQGNLSHVDWFSVHKE---KRTLIFRVRQGQGQSEPGEYEQRLSLQDR--------GATLALTQVTPQDERIFLCQGK--RPRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRPLKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESREVTVPVFYPTEKVWLEVEPVG-MLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTNDNGVLVLEPARKEHSGRYECQGLDLDTMIS-LLSEPQELLVNYVSDVRVSPAAPERQE-GSSLTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRTQLVNVAIFGPPWMAFKER--KVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRVLS------TLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPHTRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEIT-----LPPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4F9-1", "uniprot_id": "A0A8M2B4F9_DANRE", "id": "A0A8M2B4F9-1", "name": "", "aln": "--------MTYTALLLAG--LAVLTCKTWALVDVR------MEDVVEVTLKGQAKISCTYTLTEEAKMIIWFTKLPGKDQNRKRFYYSENQTEIIDQNHEYAERIKVSHSYDTEEERGSVVLILDDVQLTDEREFICMVHSVLNDVGEGRTHLKIYNSPSLPVIEREHTGISVSETEPSKVAQCKVDDGYPRPNITWYKGSFPLDPSDGEVKILESVTVKPSGLFRVESELHIKVKKEDEGAHFYCEVKYLMLGKARMTESSRFNVTVHYPTTNIKLSINPPDKLIKEGDTLELQCEGNGNP-QPIFSFRHGE-----RDLINEDNGILHLKNVKRSDSGEYVCESLDLDTGMN--YEDSLNIKVHYLDNIMVTPDETDPDQ-GHDITLTCNALSSLPTHTAWYKD--GKLLVERHVLELHNASYETTGKYMCEVMVLSLPELKKQKSVQVNVRGKPEIKEGIK-VNQMNKVNHPVNLTCYAQGYPIPNITWTLFDQQTGQIVPVLKIVNQMMDNSVHSLISVKATSDLIANCSATNELGTDDASQSIKAFVRVTTISPTSTTTEATEITVQPKS-----------PQKGGSGVIIAVIIICLLLIAIVGSVLYYLYKKGKLPCGRSGKKDFM-----KQKASKDDIVMEMKSGKS-EEAVLLQGVNGDKKSPTE-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TSS9-1", "uniprot_id": "A0AB32TSS9_DANRE", "id": "A0AB32TSS9-1", "name": "", "aln": "MDNFRNMALQNTSLLLIVLQICALAWQAWAQVDLR------MEDTVEVYMDDSAEIPCLYTFTQAPMMVMVQWFVRERDGVRVRISYSDLTMQKVDENTTYSDRISVRSNSDGE------TLTIQDVKLSDEREFFCQVSGFSAGSDERRTLLKVFDPPEPPVIEGALSGVSVSGESTAKIASCETRDGYPKPNITWYRDHIPIHPANGLVNVVTLVTRESSGLYTVQSDLHYKVTKEDKDAHFSCEVSYFVPGAVRTSESKGVNITVYYPTSSVEMWKESPQGLVKEGDTVEIHCQGDGNPPAPIIFNREQS-----DVELDSYEGLLVLKEVSRMDSGVYECHALDLDAVNNDEVLDTLQLTVHYLDPAVVVPKDSEVMLKGESLTATCNALSSLETSTVWFKK--GLEVGRGHIMQLQDATFDTAGRYDCEVTVPSLPGLLTSGSVHIIVQGAPQIKDAERDFELMEKVGAWVNLTCEVRGYPRPAITWSITGSQSQSWREVDKKE---TEDRIHSVVTLKVTTDTVAICNSTNDFGIETKIYNIKSIPFLQTPTARKTSVDN-------------------------SGVIIVVIIVSILLLAILGSVFYFLYKKGKLLCGRSGKQEIINAYSTKEKTNKDDIVVEMKAKKT-EESVLLKGINGEKKPPNDQHPEIINGVLS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *: . : * . : **. : . * : * : .. : : . : : : : * .*:.: .* : .* *:* *:* : *:::..*. * *: *: *. . ::* * :*** *:: **:. *:. .. *:: :.***: ::* * :: ***:.*:* **:.* : . : .** ..:.* **: .: : :. ::**** : ::* :*** : :. . :*:* *: . : .** * *..***:: :. :: *:*:. * * .: * .:* **:* *. * :. * : . :::*:: :: * * * . * :* * * : : * * : : : : . :**:* . *:* * *:*.: . : .:: : . *.::*.:* : :: . . . :. **:*..:*:. *::*::*:.:*::****** * ****::: : *.::*:*:*: * ** **:* .*:*:.* : ", "identical_positions": 131, "similar_positions": 191, "identity": "19.1%" }, { "cls_id": "homologset.agr.RGD:620464", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LP29-1", "uniprot_id": "F1LP29_RAT", "id": "F1LP29-1", "name": "Centrosomal protein of 78 kDa", "aln": "--------------------------MIDSVKLRRDCATDFFSHYEYLCALQDSAPLPAVR--ACLRDGVLDFNADRLRAVDWAPLLSSLRVNRDLPLVAIKSSFQPWLGESVLRSGGADAHRVCRNRVPSVRSKDISFQLCKALKGCLSVSGVLRNLELNGLILRERDLTSLTKGLSKSASLVHLSLANCPVGDGGLEIICQGIKNSVTLKTVNFTGCNLTWQGASHMAKILKYQTMRRHEETWAESLRYRRPDLDCMAGLRRITLNCNTLIGDQGASAFADSLSEDLWLRALDLQQCGLTSEGAKALLEALETNRTLVVLDIRKNPLIDHSMMKAVIRKVLQN-GRSATSEYQWVTSPSLKELPKTTKQKKKTIVLGS-SRKGKATIRVGLATKKPVSNGRKHGLSKDSYAPDPLPPGASGFLPWRTAERARRNRSFPLIKTHDLSNHLQQSDFPVTVTVESPSSSETDESEDSSESVHEVPQKTSIRQETLQEKLEECLKQLKEERVTRLKTDKRISELEHENAQLRNINFSLSEALQAQSLTSMILDDEGVLGSIENSFQKFHAFLDLLKDAGLGQLATMAGIDQSDFHLLGRPQMSSTVN-TPVEEQKGLEDENLDLKQTAVGQMQDIGFQKITSDPMVPLPLDTNQVPASTQEAAGSSRDHLGVVALEQQ--EGSAVGFIAITGSPSADGISGGRS-LEEVVLSKHSRSSSGKGSTASEPSRRQSAERHSRKDLHSDSDSPVNSKGKGPGEKRSLLNEPIKSESLKKCVSIKKENRIVTVSSKSIKSKPNLLEHSESDTIGSDFEFQEHDHSSAHLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IRU7-1", "uniprot_id": "CEP78_MOUSE", "id": "Q6IRU7-1", "name": "Centrosomal protein of 78 kDa", "aln": "--------------------------MIDSVKLRRDCAADFFSHYEYLCALQDSVPLPAVR--ACLRDGVLDFNADRLRAVDWAPLLSTLRVNRDLPLVAIKSSFQPWLGETVLRSGGADTHRICRNRVPAVRSKDISFQLCKALRGCLSVSGVLRNLELNGLILRERDLTSLTKGLSKSTSLVHLSLANCPIGDGGLEIICQGIKNSVTLKTVNFTGCNLTWQGACHMAKILKYQTMRRHEETWAESLRYRRPDLDCMAGLRRITLNCNTLIGDQGASAFADSLSEDLWLRALDLQQCGLTSEGAKALLEALETNRTLVVLDIRKNPLIDHSMMKAVIKKVLQN-GRSADSEYQWVTSPSSKEPSKTAKQRKKTIVLGS-SRKGKATIRIGLATKKPSSNGRKQGLGKDCYAPNPLPPGASGFLPWRTAERAKRSRSSSLIKTRDLSNHLKKSDFPVTVTVESPSSSETDETEDSSESVQEAPQKTSIKEETLQEKLEECLRQLKEERVIRLKADKRVSELEHENAQLRNINFSLSEALHAQSLTNMILDDEGVLGSIENSFQKFHAFLDLLKDAGLGQLATMAGIDQSDFHLLGRPQMNSTVN-TPIQEQKALEDETLHPKQTATGQMQDIRFQKITSDALIPLPLNTVQDPASAQEAVGASRDHLGVVGLEQQ--EGSAAGFIAKTGSPLAGGIPGGRSQREEEVLSKHSRSSSEKGSTASEPSRRPSAERHPRKDLLSDADPPGNSESKGPGDRRSLLNEPIKSESLKKCISIKKENRIVTVSSKTIKSKPNLLEHSESDTLGSDFELQERVHSSAHLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JTW2-1", "uniprot_id": "CEP78_HUMAN", "id": "Q5JTW2-1", "name": "Centrosomal protein of 78 kDa", "aln": "--------------------------MIDSVKLRRDSAADFFSHYEYLCALQNSVPLPAVR--ACLREGVLDFNADRLRGVDWAPLLSTLKINKDLPLVSIKSFFQPWLGDT-----GSDMNKFCRSRVPAIRYKDVTFQLCKALKGCLSISSVLKNLELNGLILRERDLTILAKGLNKSASLVHLSLANCPIGDGGLEIICQGIKSSITLKTVNFTGCNLTWQGADHMAKILKYQTMRRHEETWAESLRYRRPDLDCMAGLRRITLNCNTLIGDLGACAFADSLSEDLWLRALDLQQCGLTNEGAKALLEALETNTTLVVLDIRKNPLIDHSMMKAVIKKVLQN-GRSAKSEYQWITSPSVKEPSKTAKQKRRTIILGS-GHKGKATIRIGLATKKPVSSGRKHSLGKEYYAPAPLPPGVSGFLPWRTAERAKRHRGFPLIKTRDICNQLQQPGFPVTVTVESPSSSEVEEVDDSSESVHEVPEKTSIEQEALQEKLEECLKQLKEERVIRLKVDKRVSELEHENAQLRNINFSLSEALHAQSLTNMILDDEGVLGSIENSFQKFHAFLDLLKDAGLGQLATMAGIDQSDFQLLGHPQMTSTVSNPPKEEKKALEDEKPEPKQNALGQMQNIQFQKITGDARIPLPLDSFPVPVSTPEGLGTSSNNLGVPATEQR--QESFEGFIARMCSPSPDATSGTGSQRKEEELSRNSRSSSEK---------KTKTESH----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFH6-1", "uniprot_id": "CEP78_DROME", "id": "Q9VFH6-1", "name": "Protein Cep78 homolog", "aln": "MSVSRVTMMRKGHSGEVARKPNTVVVSVPPLVKKSSKSRSFHFRYLELCRAKNLTPVPEIRSKSNATTTFLELCGDKLAVSDWQLLTEALHYDLVLQQLVVR--LRRTYPQTNIDPIDTEKRARLFRQRPVIYTRFIFNSLVQAIANCVSSNKNLSVLKLEGLPLQDGYIETIAKALADNECLESVSFRKSNIGDKGCEVVCNTAKYLNRIEVFDLSECGLTSKGAEHVADMLKMQKITRFTEGWEKSLRYRSVDVNTIGGLRTVLLADNPEIGDVGIRWITEVLKEDAWIKKIDMEGCGLTDIGANLILDCLELNTAITEFNVRNNEGISKFLQRSIHDRLGCLPEEKQEPEYDLSCVNGLQSLPKNKKVTVSQLLSHTKALEEQLSFERTLRKKAEKLNEKLSHQLMRPDSNHMVQEKAMEGGSQTNISREYVARNDVMPEVIKNSQSYRQSHFNRLVNSAATSPEVTPRSE--IVTLRKEQQLQRQQPPPMEVKHLSLEQQIRNLRDVQKKVDLDVEEEEEEEEEEQQAEESQSESEPQNEEQQHYEQQMQVQRKHLQVRKVRSEIKYVENNPKEAAKKNRESKSDHEFANERDFKLNPSVQFETDIGDNVMVNPGHRYEGGGGDTAYVYNYEHEQQQQPVKRGYEHGYVVGVGDGSHRRQRQSQLVEALVQKRVPGASDGHVAQFVSNLERQANAGKTGKKRLKPRPEDDLQVPVGDMHMESSYMSRSEELSSTDVTLENSDYETEATDSTLLSSSKYSSMHVFVRRKQSESMSLTEEAGDGDAGGGGGSGDFGDQNVISPANVYMSLQLQKQREQSA-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : . : .*. :* ** :: .*:* :* : .*:: .*:* ** * .:*: : * : :: :: :: .:: . : * : : : .* :*: .*:* . * *:*:** *:: : ::*.* .. .* :*: :. :** * *::*: * ::..::: *.** :** *:*.:** *.: *. * * :***** *:: :.*** : * *. *** * ::: *.** *:: :*:: ****. **: :*:.** * ::. :::*:* *.: : ::: :: .. .**: . :. .*. * :: : . : : ::. * .* . : : : . . . .* *. : :. . .: ::. * *. :.*.. . . : :::: : . .:: * . :*::: * : *.* :.* *.*: : :: : * **: :. . :: * . : : : : ::. . . . .: :* ::..:*. . .: : : : . . ::: : : : . . : * . *: : *.:* * . : :. .. . :* ", "identical_positions": 113, "similar_positions": 240, "identity": "13.73%" }, { "cls_id": "homologset.agr.RGD:620465", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08565-1", "uniprot_id": "CXCR4_RAT", "id": "O08565-1", "name": "C-X-C chemokine receptor type 4", "aln": "-----MEIYTSDNYSEEVGSGDYDSNKEPCFRDENENFNRIFLPTIYFIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAMADWYFGKFLCKAVHIIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKAVYVGVWIPALLLTIPDIIFADVSQG-----DGRYICDRLYPDSLWMVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYVGISIDSFILLEVIKQGCEFESVVHKWISITEALAFFHCCLNPILYAFLGAKFKSSAQHALNSMSRGSSLKILSKGKRGGHSSVSTESESSSFHSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70658-1", "uniprot_id": "CXCR4_MOUSE", "id": "P70658-1", "name": "C-X-C chemokine receptor type 4", "aln": "MEPISVSIYTSDNYSEEVGSGDYDSNKEPCFRDENVHFNRIFLPTIYFIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAMADWYFGKFLCKAVHIIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKAVYVGVWIPALLLTIPDFIFADVSQGDISQGDDRYICDRLYPDSLWMVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYVGISIDSFILLGVIKQGCDFESIVHKWISITEALAFFHCCLNPILYAFLGAKFKSSAQHALNSMSRGSSLKILSKGKRGGHSSVSTESESSSFHSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61073-1", "uniprot_id": "CXCR4_HUMAN", "id": "P61073-1", "name": "C-X-C chemokine receptor type 4", "aln": "MEG--ISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEA-----DDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*******:**:******* ******:** :**:******* ****************************************************:*:****:*******:****************************************.****************:***:**:. *.******:**:.**:************************************************************:********** :*****:**. *******************************:******.*:********************************", "identical_positions": 316, "similar_positions": 28, "identity": "88.02%" }, { "cls_id": "homologset.agr.RGD:620466", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31230-1", "uniprot_id": "AIMP1_MOUSE", "id": "P31230-1", "name": "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "aln": "-------------------MATNDAVLKRLEQKGAEADQIIEYLKQQVALLK----EKAILQATMREEKK----------LRVENAKLKKEIEELKQELILAEIHNGVEQVRVRLSTPLQTNCTASESVVQSPSVATTASPATKEQI-KAGEEKKVKEKTEKKG------------EKKEK-QQSAAASTDSKPIDAS---------RLDLRIGCIVTAKKHPDADSLYVEEVDVG-EAAPRTVVSGLVNHVPLEQMQNRMVVLLCNLKPAKMRGVLSQAMVMCASSPEKVEILAPPNGSVPGDRITFDAFPGE-PDKELNPKKKIWEQIQPDLHTNAECVATYKG-------APFEVKGKG-VCRAQTMANSGIK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G079-1", "uniprot_id": "Q4G079_RAT", "id": "Q4G079-1", "name": "", "aln": "----MMRVRKRIFCRFWGKMATNDAVLKRLEQKGAEADQIIEYLKQQVALLK----EKAILQATLREEKK----------LQVENAKLKKEIEELKQELIQAEIHNGVKQVPVPSSSSLETHCSVSESVTRSASVTTTTMTG------GGGEEKKVKEKTEKKG------------EKKEKKQQSAAASADSKPVDVS---------RLDLRIGCIVTAKKHPDADSLYVEEVDVG-EAAPRTVVSGLVNHVPLEQMQNRMVVLLCNLKPAKMRGVLSQAMVMCASSPEKVEILAPPNGSVPGDRITFDAFPGE-PDKELNPKKKIWEQIQPDLHTNDECVATYKG-------APFEVKGKG-VCRAQTMANSGIK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12904-1", "uniprot_id": "AIMP1_HUMAN", "id": "Q12904-1", "name": "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "aln": "-------------------MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLK----EKAILQATLREEKK----------LRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKG------------EKKEKKQQSIAGSADSKPIDVS---------RLDLRIGCIITARKHPDADSLYVEEVDVG-EIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGE-PDKELNPKKKIWEQIQPDLHTNDECVATYKG-------VPFEVKGKG-VCRAQTMSNSGIK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TE84-1", "uniprot_id": "A0AB32TE84_DANRE", "id": "A0AB32TE84-1", "name": "", "aln": "-------------------MSKDKPPTSRADP--PQQEQMMEYFTQQILFLK----EKAMLQASVREEKK----------LLVENAKLKKDIDDLKNLLQDTQKR---KAVKLRQERALSASIASTSAQLGEPAPFTHTAPS------ATQTHAHTHHDGRRRR------------ERRGVSCESVCVLSREQKLDVS---------RLDLRVARILDVRKHPDSESLYVQEVELG-EHAPRTVVSGLTNHVPPEQLLGSLVVLLCNVRSVKVRGVQSQARLLCAVNQERMEPLTPPTGAQPGDRVTFQLYPGE-PEKELNPKQRLWERLLPDLRIDARGVATYRG-------VAFEVRGKG-LCRAPNITSGNIK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7K8-1", "uniprot_id": "A1Z7K8_DROME", "id": "A1Z7K8-1", "name": "", "aln": "----MLRRAATTVGSACKNYGQNCSKFARNKRTMADLQQIASNNERAEALINSIEAEISGIQQQLVERQKQE--------LIKENAALAKEVEAALAQLVQLELRNGKKQIPVPGARGFCTSAAP--VVMPAEAGPATAAPA-------APAPKPAKEPKEKKS------------KEKKPAAEKPAAAP-EAPVDVG---------RLDLRVGKIVEVGRHPDADSLYLEKIDCG-EAAPRTVVSGLVKFVPLEEMQNRLVVVMCNLKPAKMRGVTSEAMVMCASTPEKVEVLSPPAGAVPGDLVHCEGYPRQ-PDAQLNPKKKIFESCAPDLKTNGELVACYKG-------AALHVPGKG-NVVAQTLKNVNVK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46672-1", "uniprot_id": "ARC1_YEAST", "id": "P46672-1", "name": "tRNA-aminoacylation cofactor ARC1", "aln": "MSDLVTKFESLIISKYPVSFTKEQSAQAAQWESVLKSGQIQPHLDQLNLVLRDNTFIVSTLYPTSTDVHVFEVALPLIKDLVASSKDVKSTYTTYRHILRWIDYMQNLLEVSSTDKLEINHDLDLPHEVIEKKKKAPAGGAADAAAKADEDVSKKAKKQDHPRGKPDEETLKKLREEAKAKKAAKKAANAKQQQEQQNKAPEKPKPSAIDFRVGFIQKAIKHPDADSLYVSTIDVGDEEGPRTVCSGLVKHFPLDAMQERYVVVVCNLKPVNMRGIKSTAMVLCGSNDDKVEFVEPPKDSKAGDKVFFEGFGDEAPMKQLNPKKKIWEHLQPHFTTNDGLEVIFKDEEEKDHPVRKLTNAKGESFKVASIANAQVR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . *: : .:. : : : : * .. : . * : : : . .:. . : : : . . . . : . :*:*:. * . :***::***:. :: * * .**** ***.:..* : : *:::**::..::**: * * ::*. . :::* : ** .: .** : : : : * :****::::* *.: : . ::. . . .** . .: . ::", "identical_positions": 44, "similar_positions": 98, "identity": "11.7%" }, { "cls_id": "homologset.agr.RGD:620467", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQF6-1", "uniprot_id": "DPYL5_MOUSE", "id": "Q9EQF6-1", "name": "Dihydropyrimidinase-related protein 5", "aln": "------------MLANSASVRILIKGGKVVNDDCTHEADVYIESGIIQQVG--RELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKE-TSLVEAYEKCRALADPKVCCDYALHVGITWWAPKVKAEMETLVRE--KGVNSFQMFMTYKDLYMLRDSELYQVFHACRDIGAIPRVHAENGELVAEGAKEALDLGITGPEGIEISHPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAA--KMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVVWERGVVGGKMDENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVYKKLVQREKT-------LKVRGVDRTPYLG-DVAIVVHP-------GKKEMGTPLADTPTRPVT-RHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHU0-1", "uniprot_id": "DPYL5_RAT", "id": "Q9JHU0-1", "name": "Dihydropyrimidinase-related protein 5", "aln": "------------MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVG--RELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKE-TSLVEAYEKCRALADPKVCCDYALHVGITWWAPKVKAEMETLVRE--KGVNSFQMFMTYKDLYMLRDSELYQVFHACRDFGAIPRVHAENGELVAEGAKEALDLGITGPEGIEISHPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAA--KMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVVWERGVVGGKMDENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVYKKLVQREKT-------LKVRGVDRTPYLG-DVAVVVNP-------GKKEMGTPLADTPTRPVT-RHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BPU6-1", "uniprot_id": "DPYL5_HUMAN", "id": "Q9BPU6-1", "name": "Dihydropyrimidinase-related protein 5", "aln": "------------MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVG--RELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKE-TSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVRE--KGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAA--KMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKT-------LKVRGVDRTPYLG-DVAVVVHP-------GKKEMGTPLADTPTRPVT-RHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IPQ2-1", "uniprot_id": "Q8IPQ2_DROME", "id": "Q8IPQ2-1", "name": "dihydropyrimidinase", "aln": "MSTSPKPVKKVPIHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKH-ESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKE--LGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEGSLCSTPSVRGRVDGKRDLQESSFSIS--EELDRSGVRACIKVKNPPGGKSSGFW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32375-1", "uniprot_id": "ALN_YEAST", "id": "P32375-1", "name": "Allantoinase", "aln": "----------MPINAITSDHVIINGANKPATIVYSTESGTILDVLEGSVVMEKTEITKYEIHTLENVSPCTILPGLVDSHVHLNEP--GRTSWEGFETGTQAAISGGVTTVVDMPLNAIPPTTNVENFRIKLEAAEGQMWCDVGFWGGLVPHN---LPDLIPLVKAGVRGFKGFLLDSGVEEFPPIGKEYIEEALKVLAEEDTMMMFHAELP--KAHEDQQQPEQSHREYSSFLSSRPDSFEIDAINLILECLRARNGPVPPVHIVHLAS----MKAIPLIRKARASGLPVTTETCFHYLCIAAEQIPDGATYFKCCPPIRSESNRQGLWDALREGVIGSVVSDHSPCTPELKNLQKGDFFDSWGGIASVGLGLPLMFTQGCS-----LVDIVTWCCKNTSHQVGLSHQKGTIAPGYDADLVVFDTASKHKISNSSVYFKNKLTAYNGMTVKGTVLKTILRGQVVYTNANGVSKTPLGQTLLDSRR-----------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::. : .: .. : ::.. :: . * *: :.: ::** :*. .*:: . . .. :.* **:**: **.* ::. * : :: : *: :: ** .: *:. :: * : *.:.* : : : .. : :.:. . . : .*** *. :. . .. *:*:..* :* : . . *: *:: :: * : . . : *::. * . .. * . * :. : . **: . . : * : * ** . *: .* :.::: :* :*: ..*::: ..: :** * * ***:*:::. :.:.** .: .:. ::.* :*. .: **:: .. *: ", "identical_positions": 63, "similar_positions": 156, "identity": "10.52%" }, { "cls_id": "homologset.agr.RGD:620469", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVC0-1", "uniprot_id": "SEPT7_RAT", "id": "Q9WVC0-1", "name": "Septin-7", "aln": "---------------------------------MSVSARSAAAEERSVN-----------------------------------------------------------CSTM-AQPKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLT-DLY---------------------SPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNS-NCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQGHKIKIYEFPETDDE--EENKLVKKIKDRLPLAVVGSNTIIE-VNGKRVRGRQYPWGVAE----VENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEEEKANWEAQ---------QRILEQQNS--SRTLEKNKKKGKIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55131-1", "uniprot_id": "SEPT7_MOUSE", "id": "O55131-1", "name": "Septin-7", "aln": "---------------------------------MSVSARSAAAEERSVN-----------------------------------------------------------CGTM-AQPKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLT-DLY---------------------SPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNS-NCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDE--EENKLVKKIKDRLPLAVVGSNTIIE-VNGKRVRGRQYPWGVAE----VENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEEEKANWEAQ---------QRILEQQNS--SRTLEKNKKKGKIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16181-1", "uniprot_id": "SEPT7_HUMAN", "id": "Q16181-1", "name": "Septin-7", "aln": "---------------------------------MSVSARSAAAEERSVN-----------------------------------------------------------SSTMVAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLT-DLY---------------------SPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNS-NCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDE--EENKLVKKIKDRLPLAVVGSNTIIE-VNGKRVRGRQYPWGVAE----VENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQ---------QRILEQQNS--SRTLEKNKKKGKIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NZC4-1", "uniprot_id": "A0A8M1NZC4_DANRE", "id": "A0A8M1NZC4-1", "name": "Septin", "aln": "-----------------------------------------------------------------------------------------------------------------MAQKNLEGYVGFASLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLT-DLY---------------------SGEYPGPSNRIKKTVQVEQSKVLMKEGGVQLLLSIVDTPGFGDAVDNS-NCWQPVIDHIDSKFEDYLNAESRVNRRQMPDSRVHCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMREILEHKIKIYEFPETDDE--EENKIVKTIKDRLPLAVVGSNTIIE-ANGKKVRGRQYPWGVAE----VENGDHCDFTLLRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTCNGIDNNKAKGQLTKSPLAQMEEERREHVTKMKKMEMEMEQVFEMKVKEKVQKLKDSEGELQRRHEQMKKNLEAQHKELEERRRQFEEERSTWETQ---------QRILEQQK----MTLEKNKKKGKIF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PMV4-1", "uniprot_id": "A0A8M9PMV4_DANRE", "id": "A0A8M9PMV4-1", "name": "Septin", "aln": "---------------------------------MRLQETENHAEKGMEKDSIQL----------------------------------DKALTVIWSEIHCLHDDIELMMELIQNQRNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLT-DLY---------------------SKDYPGPSQRIKKTVQVEQSKVLIKEGGVQLTLTIVDTPGFGDAVDNS-NCWQPVINYIDSKFEDFLNAESRVNRRQMPDNRVHCCLYFIAPSGHGLKPLDIEFMKRLHDKVNVIPLIAKADTLTPEECQLFKKQIMKEIQEHKIKIYEFPDTEDD--EDSKLIRKIKEKMPLAVVGSNVVIE-VNGRKVRGRQYPWGVAEEGIVVENGEHCDFTVLRNMLIRTHMQDLKDVTNNVHYENYRSKKLAAVTCNGVDATKNKGQLTKSPLAQMEEERREHVMKMKKMETEMEQVFEMKVKEKKQKLKDSEAELERRHEQMKKNLEAQYKELEEKRRQFEDEKANWEAQ---------QRILEQQKLDASKTMEKNKKKGKIF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40797-1", "uniprot_id": "PNUT_DROME", "id": "P40797-1", "name": "Protein peanut", "aln": "MNSPRSNAVNGGSGGAISALPSTLAQLALRDKQQAASASASSATNGSSGSESLVGVGGRPPNQPPSVPVAASGKLDTSGGGASNGDSNKLTHDLQEKEHQQAQKPQKPPLPVRQKPMEIAGYVGFANLPNQVYRKAVKRGFEFTLMVVGASGLGKSTLINSMFLS-DIYN--------------------AEQYPGPSLRKKKTVAVEATKVMLKENGVNLTLTVVDTPGFGDAVDNS-NCWVPILEYVDSKYEEYLTAESRVYRKTISDSRVHCCLYFIAPSGHGLLPLDIACMQSLSDKVNLVPVIAKADTMTPDEVHLFKKQILNEIAQHKIKIYDFPATLEDAAEEAKTTQNLRSRVPFAVVGANTIIE-QDGKKVRGRRYPWGLVE----VENLTHCDFIALRNMVIRTHLQDLKDVTNNVHYENYRCRKLSEL---GLVDGKAR-LSNKNPLTQMEEEKREHEQKMKKMEAEMEQVFDMKVKEKMQKLRDSELELARRHEERKKALELQIRELEEKRREFEREKKEWEDVNHVTLEELKRRSLGANSSTDNVDGKKEKKKKGLF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32457-1", "uniprot_id": "CDC3_YEAST", "id": "P32457-1", "name": "Cell division control protein 3", "aln": "MSLKEEQVSIKQDPEQEERQHDQFNDVQIKQESQDHDGVDSQYTNGTQNDDSER-----------------------FEAAESDVKVEPGLGMGITSSQSEKGQVLPDQPEIKFIRRQINGYVGFANLPKQWHRRSIKNGFSFNLLCVGPDGIGKTTLMKTLFNNDDIEANLVKDYEEELANDQEEEEGQGEGHENQSQEQRHKVKIKSYESVIEENGVKLNLNVIDTEGFGDFLNNDQKSWDPIIKEIDSRFDQYLDAENKINRHSINDKRIHACLYFIEPTGHYLKPLDLKFMQSVYEKCNLIPVIAKSDILTDEEILSFKKTIMNQLIQSNIELFKPPIYSNDDAENSHLSERLFSSLPYAVIGSNDIVENYSGNQVRGRSYPWGVIE----VDNDNHSDFNLLKNLLIKQFMEELKERTSKILYENYRSSKLAKLG----IKQDNSVFKEFDPISKQQEEKTLHEAKLAKLEIEMKTVFQQKVSEKEKKLQKSETELFARHKEMKEKLTKQLKALEDKKKQLELS-------------------INSASPNVNHSPVPTKKKGFLR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ******.**:* :*:::*.**.*.*: ** .*:**:**::::* . *: . : . * . ::.* :: : :::*.**:* *.::** **** ::*. :.* *::. :**:::::* **.:: *: : *.*::.***** *:** * ***: *: : :* *::*:***:* :* :* *** *:.:: :*:::. * :: *: : . : . :* **:*:* ::* .*.:**** ****: * *:* *.** *:*::*: .:::**: *.:: *****. **: : . .*::: :**: * *: *:* **: **: **.** :**:.** ** **:: *: * * : **::::::* . : . *** : ", "identical_positions": 143, "similar_positions": 144, "identity": "25.09%" }, { "cls_id": "homologset.agr.RGD:62047", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17225-1", "uniprot_id": "PTBP1_MOUSE", "id": "P17225-1", "name": "Polypyrimidine tract-binding protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIVPDI------AVG-----------------------TKRGSDELFSTCVSNG---------PFIMSS-----------------------------SASAANGNDS------KKFKGDNRSAG---VPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASA-----------------------AAVDAG---MAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIMSASPYAGAGF------PPTFAIPQAAGLSVPNVHGALAPLA-IPSAAAAAAAS-RIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00438-1", "uniprot_id": "PTBP1_RAT", "id": "Q00438-1", "name": "Polypyrimidine tract-binding protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIVPDI------AVG-----------------------TKRGSDELFSTCVSNG---------PFIMSS-----------------------------SASAANGNDS------KKFKGDNRSTG---VPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMSTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASA-----------------------AAVDAG---MAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIMSASPYAGAGF------PPTFAIPQAAGLSVPNVHGALAPLA-IPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26599-3", "uniprot_id": "PTBP1_HUMAN", "id": "P26599-3", "name": "Polypyrimidine tract-binding protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGIVPDI------AVG-----------------------TKRGSDELFSTCVTNG---------PFIMSSN----------------------------SASAANGNDS------KKFKGDSRSAG---VPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASA-----------------------AAVDAG---MAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIISASPYAGAGF------PPTFAIPQAAGLSVPNVHGALAPLA-IPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKSTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K6W9-1", "uniprot_id": "A0A0B4K6W9_DROME", "id": "A0A0B4K6W9-1", "name": "", "aln": "MMSCPIPMPMPISSLHKSEFEPVNIGVKQMQLLHAPASTHPHPHPHQHPQHSAASAAAYQAMQVHQQQHQQQQQAAVFHHQVAAIAAQQQQQQQQAQVQHQQQMQQQFHYQAQAQAQAQAMLQTYMQLQVNSAVGVSTAPATPTKPVAAQIPGAISGPIAGPVPVSVPTQFFTAPSTPLTIIPAAAVASSAMFATAATPTSAATTPTNNVNNTVNLSAVSRTTTTTTKKQPQAVADAVLSAVGGNVGTAVGGGTISSLLGPEPLPIMPHHLPLASVRGCSSASSGCSSASSDCSMPSPTSLHLSSPKKVRIDEQYIYKLNYLRGSDELLSQAAVMAPASDNNNQDLATKKAKLEPGTVLAGGIAKASKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAGGNTNAAGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVDIMPTAGGLMNTNDLLLIAARQRPSLSVNGLGAPGVLPPFALGLGTPLTGGYNNALPNLAAFSLANSGALQTTAPAMRGYSN-VLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSNIPSSCSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESNHLRVSFSKSNI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.::. : *** : **... * * : . .: :** *.*::.*:. *:: .. :* .*:***:*::* : *.:**:**:***:***:*:*********** * :*.:**. ** ..* :**: :*:*****:*****.. *:: *:: .. ...... *.*:*:* :**:** * .* ..***:***.*:***:**:*****.::*.****:******.****:**.*. ****** ********.******* ****:************:*.* **.*:. .: * .. :.: .:: :. ..: .* . * * **..* . * .*. :.: : * :.: : : *.: * .* ******** * ***::** **************:***:.**:***: .** ******: :* **.:*: **** ****:*** * ***:**...************:***:************.* **:*:* *:**. **.**** *******:*: ****** ***.:***:*.*.:*********.*", "identical_positions": 304, "similar_positions": 161, "identity": "33.82%" }, { "cls_id": "homologset.agr.RGD:620470", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QWG5-1", "uniprot_id": "INP4B_RAT", "id": "Q9QWG5-1", "name": "Type II inositol 3,4-bisphosphate 4-phosphatase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MEIKEEGTSEEGQHFLPAAQANDPEDIQFTS---IQKSPNEPQLEFILACKDLVAPVSDRKLNTVVQVSVIHPVEQTLTR--YSSTEIVEGTKDPLFLTGVTFPSDYPIYEETRIKLTVYDVKDKPHDTIRTSVLPEHKDPPPEVARSFLGCASFKVGELLKSKEQLLSLSLRTSDGGKVVGTIEVSLVKMGEIEDGDTDHITTDVQGQKCALVYDSTAPESLSGKENLPFMNAVLRNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQELKELGDLSPHWDNLRNNVLSHCDQMVTMYQDILTELSKET--GSSFKSSSSKGEKTLEFVPINLHLQRMQVHSPHLK-DALYDVITVGAPAAH-FQGFKNGGLRKLLHRFETERR--------NTGYQFIYYSPENTAKAKEVLSSINQLQPLVATHADLLLT----------------------------------------------------------------------------------------------------------SASQHSPDSLRSSLKLLSEKTELFVHAFKDQLVRSALLALYTARPGGILRK----PPSPKVSTEEK-----------------------SSQHDSPQQLRRQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAKVDKLI--------------------------------------------------ERDSRNDKSTGGDSSKDGDADPNLEDSLTSHPREDWYEQLHPLILTLKECMAEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLHTSLHDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDLRKVAFKITEATSND---VLPVLTGRREHYVVEVKLPATVFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELVQEYYSIFMEKMPPDYISHFQEQNDLKGLLDNLHQNIQAKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRR-----------EGCRIENVLKNIKCRRYAFNMLQLMA---FPKCYRPPEGTYGKADT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P1Y8-1", "uniprot_id": "INP4B_MOUSE", "id": "Q6P1Y8-1", "name": "Type II inositol 3,4-bisphosphate 4-phosphatase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MEIKEEGTSEEGQHFLPAAQANDPEDIQFTS---IQKIPNEPQLEFILACRDLVAPVSDRKLNTVVQISVIHPVEQTLTR--YSSTEIVEGTKDPLFLTGVTFPPDYPIYEETRIKLTVYDVKDKSHDTIRTSVLPEHKDPLPEVARSFLGCASFKVGELLKSKEQLLSLSLRTSDGGKVVGTIEVSLVKMGEIEDGDTDHITTDVQGQKCALMYESTAPESLSGKENLPFMNAVLRNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQELKELGDLSPHWDNLRKNVLSHCDQMVTMYQDILTELSKET--GSSFKSSSSKGEKTLEFVPVNLHLQRMQVHSPHLK-DALYDVITVGAPAAH-FQGFKNGGLRKLLHRFETERR--------NTGYQFIYYSPENTAKAKEVLSSINQLQPLIATHADLLLT----------------------------------------------------------------------------------------------------------SASQRSPDSLKSSLKLLSEKTELFVHAFKDQLVRSALLALYTARPGGILKK----PPSPNVSTEEK-----------------------STQHDTP-QLRRQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAKVDKLI--------------------------------------------------ERDSHNEEGAGGSSSKDGEADHTLEDSITSHPREDWYEQLHPLILTLKECMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLHTSLHDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDLRKVAFKITEATSND---VLPVLTGRREHYVVEVKLPATVFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELVQEYYSIFMEKMPPDYISHFQEQTDLKGLLDNLHQNIQAKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRR-----------EGCRIENVLKNIKCRRYAFNMLQLMA---FPKCYRPPEGTYGKADT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15327-1", "uniprot_id": "INP4B_HUMAN", "id": "O15327-1", "name": "Inositol polyphosphate 4-phosphatase type II", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MEIKEEGASEEGQHFLPTAQANDPGDCQFTS---IQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTR--YSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHITTDVQGQKCALVCECTAPESVSGKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKET--GSSFKSSSSKGEKTLEFVPINLHLQRMQVHSPHLK-DALYDVITVGAPAAH-FQGFKNGGLRKLLHRFETERR--------NTGYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLN----------------------------------------------------------------------------------------------------------SASQHSPDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKK----PPSPKSSTEE------------------------SSPQDQPPVMRGQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVDKLI--------------------------------------------------ERDGGSE-GSGGNN--DGEKEPSLTDAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLQTSLYDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSND---VLPVITGRREHYVVEVKLPARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRR-----------EGCRIENVLKNIKCRKYAFNMLQLMA---FPKYYRPPEGTYGKADT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58FX12-1", "uniprot_id": "A0AC58FX12_DANRE", "id": "A0AC58FX12-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MRDYKRGLIKTAQTLQSGDDRSIMRDPACRQ---PRRVKKLTVDGHKMVTDHIISPSSRK---------AQHFLFACQTT--ADQIIIKQRTRDPVFPSGVSFPLDCPVYNDTFIKVSVYGVSDE------------------QQSSNFLGTSRFSVADLLHSKDQQLSLSLRTADDSVTVGTVLVSRMKMGEIEDGEVDHITADMH-QKCTLVYES--SHGINDKENGPIMNTVFQNAVCKVYRFQTVDSKWMLVREQMAECTLSFSIPKQLIGLCIQEDTCRIQELKDLGELSPHWHNLRKDVISRYEQIIKEYQDTLVELEKLT--GPSFKPSCSKGQKYLEFIPINLHTQRMRVTCPRKT-DSCYDVVTVGAPAAH-SQGFKNGGLQKLLSKYESEKKS------YSTAYQCIYYPPEQTTKAREILSVVSQLQPHITALADQLLQ----------------------------------------------------------------------------------------------------------SPR----DALRDTLKSLEDKTEQFVHALKDELVKSALLALHAARPGYVSKSQTSAPSSPPEPNEEPNVVCNNVNSS------------QTPLKESKASPVRSDSIPHHKEYDEEEWDRVWASVAKSLNSVIAMVEKLQ--------------------------------------------------EQDNNNQESTPCQTLADVITSHSPDRPMD---VVDWRDQLGVLVQSLKECVLDVAERARHSVIFVLLQEAACSTAQGLQLQQRRDTVFSQALTALACGFVMRLYAGLEDKGFLRQLHAVGLVAQFESLLSTYSEEIGMLEDMEVGISDLTRVTFRITEALSEDSASLTPIISGRRDRYTVEVPLPHDAFQTLPDELRQGKLLHVIPVLFNVGINEQQTIAERFGDISLQERINQKNFEILEGYYKSLSNTLPSECLPSFQTQTDIKELLETLGQNVVTKKRKNVEILWLAGTICRRMNGIRFTSCKSAKDRTSMSVTLEQCCLLRDEHQLNKDYFVRALDCMRSGRLAQGELAQWDDPEAGSIAINKPASRHFYPIALLLVSSHLLVVWLILSLVFLLAKYQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY47-1", "uniprot_id": "Q9VY47_DROME", "id": "Q9VY47-1", "name": "phosphatidylinositol-3,4-bisphosphate 4-phosphatase", "aln": "MRFNKPELNSLASNPATRFDKEGLLIITDRQEGFLWRSSEVRVERWCKLRGNLLFYLKDKDPKSAVAGLLVLENCRARIQNEERDSEGYVFDLDFKDSPSERFITRSSAERLAWVQCIEHASSEKLNALIRQLKEQIVSQSRQPSSGASSSMGNHIDLGMPLEQQMQEQLQLHGQPAEELSVPVPTEVVAPFEELDLSELPICETALSCDTLPLDTLGRPPNPQVVCSLLPTAGEDCVWREHARTELQERTRTPQFLCTMRFQRSAGLSASTRLRFSVFDVRERMTLTAVPLGHAEVALGVIQDTSRLRLPLTSPRGECGFITLASWSPDAAVEPGQSGNGPPRSSTQLFDGSAGAGGATTSSRRAHRRTQSLPPKLGVRLFVPQQCG--LQRVCSNPRLRTYRLHSSLGADISVQETLLESRLCCQLPQQLLSIWIQREKELLQEISGMGELSGEWRWRQMNLLEEHLRLLKDYSQAKQNIQQLARDGVSFKRSSAKADESLEFLPVNLHVQRMWAQNDTLQRRGLLDVVTVGAFTRHDPKGRKCGGLIKLLQESKSWKLEQSNACKVQAANDAVQATKQLRKEIVELMSQLLQLASRRSSMDMMPLCNQMVARTRTLLNLWEPSIVEEAVAFIERHRIIEEPENVLMEPMSPFRKITQQLTALELKSPELEDFATPVVAPPDLWPRGQPPLMRSNSWHPSNSSPSSSLDIRAIDSLQHVVKCYNDHLRSLEQGRQPGRQADDEEQEEATYQSLPVAWQTQSEVSAGTQIPPSDNPADLSVLQLIDLDEIGRQAQRQRHHQPPAGFLDTKLMSSSPSANYYRPTEEPEPLDLTQLNIEASVMCLVSKLKFFCGRCDSPAIRLRHPKAPIKREGFAVAPQQAPDVIAASAASGKQAPNLALDLKPQSVDSDGITTTGSVAVKKGNKFTDGLDLSMTTDWAAELRPSMRKLRHAMDRLLKTARLMHSVQRLQQDMRCNRLQASIMYRRDVCFSQALTALVSSLMLRLWGSELDMGYLVMLRDLGPLAYFEGLLTLYGNEADMWSDMCIAIEDLSAVSFQLVRAQGEVAQTPTPRITGSRQALEVQLPVPEHSLPGNGNSIS----FKITPVFFNIGINEKASFAETLGQTKEQHRSNWDNYLRLSQYFGRYRKLG----LGSVDTGESLQSLLGFMEQQLRANVSKNVKILHLAEDACRLMDGLRFTSCKSAKDRTGMAVTLEQCRVLVREFQLPAKHVPYALSTMRS-----------EGTRMDNVLKNIGKRKYAFNRTQVSF---LPAMYRPPVGSYGKAQT-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. : . : . : . : : : . : : *: * * : * . : .* ::.:*:.* :. : : .: . . . . *. * :. .. :: :: : . . :: :: * *. : **: : . : ::* : *. *. :*::*:.: *:.: **:. :*:** .* : ::: . :::. *.: ::.: : * *** *.:*.:: ***:*:*** *** . . **:**** : * :* * *** *** . :: : .:. : : . : : *::* : ** . :: * .. .. .. *: *.: : :* .:: .:: :* .* . ... . : : : .: :: : * * . .: *: .::: :. : : :. .. . . : ** :* : .*:..: : : *: . **: . : *** *****:.*...::::* . * *:* *: :* :. :*.**: *.:* .* .** :.*.** *:*:: .* .: * ::* *: *:: :* : .: ::: **:**:****: ::** :*: . *. * .*: :. *: : : .: .:: ** : *:: :: ***:*: ** ** ::*:***.********.*:****** :* *.** ... **. ** :. . .: * :: : : : : : *. ", "identical_positions": 167, "similar_positions": 283, "identity": "12.8%" }, { "cls_id": "homologset.agr.RGD:620471", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M8W4-1", "uniprot_id": "SOX5_RAT", "id": "F1M8W4-1", "name": "Transcription factor SOX-5", "aln": "MLTDPDLPQEFERMSSKRPASPYGETDGEVAMVTSRQKVEEEESERLPAFHLPLHVSFPNKPHSEEFQPVSLLTQEACGPRTPAAQHSTMEVDGNK--VMSSLAPYNSSTSPQKAEEGG---RQSGESVSSAALGTPERRKGSLADVVDTLKQRKMEELIKNEPEDTPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQ-VQGQLPPLMIPVFPPDQRTLAAAA-QQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQFYAAQLAAMQVSPGGKLLGLPQGNLG-AAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPASPTSPHMPALRINSGAGPLKASVPAALASPSARVS---------TIGYLNDHDAVTKAIQEARQMKEQLRREQQALDGKVAVVNSIGISNCRTEK----EKTTLESLTQQLAVKQNEEGKFSHGMMDFNMSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYEEYEEEEEDPDVDYGSDSENHIAGQAN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35710-1", "uniprot_id": "SOX5_MOUSE", "id": "P35710-1", "name": "Transcription factor SOX-5", "aln": "MLTDPDLPQEFERMSSKRPASPYGETDGEVAMVTSRQKVEEEESERLPAFHLPLHVSFPNKPHSEEFQPVSLLTQETCGPRTPTVQHNTMEVDGNK--VMSSLSPYNSSTSPQKAEEGG---RQSGESVSSAALGTPERRKGSLADVVDTLKQRKMEELIKNEPEDTPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQ-VQGQLPPLMIPVFPPDQRTLAAAA-QQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQFYAAQLAAMQVSPGGKLLGLPQGNLG-AAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPASPTSPHMPALRINSGAGPLKASVPAALASPSARVS---------TIGYLNDHDAVTKAIQEARQMKEQLRREQQALDGKVAVVNSIGLSNCRTEK----EKTTLESLTQQLAVKQNEEGKFSHGMMDFNMSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPSAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGAKGEEPHIKEEIQAEDINGEIYEEYDEEEEDPDVDYGSDSENHIAGQAN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35711-1", "uniprot_id": "SOX5_HUMAN", "id": "P35711-1", "name": "Transcription factor SOX-5", "aln": "MLTDPDLPQEFERMSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLLTQETCGHRTPTSQHNTMEVDGNK--VMSSFAPHNSSTSPQKAEEGG---RQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQ-VQGQLPPLMIPVFPPDQRTLAAAA-QQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLG-AAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASVPAALASPSARVS---------TIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEK----EKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEEDDPDVDYGSDSENHIAGQAN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0N4-1", "uniprot_id": "A0A8M9Q0N4_DANRE", "id": "A0A8M9Q0N4-1", "name": "", "aln": "MLTEPELPQEFNRMSSKRPASPYGGTDGEVVMATSRQRLEDEEVDGHAVIHLPLSS------YCSKVSPRSPRLLD-----SPPTLHANMDQDGSKGLALSPYAQHNSSTSPSKQQQEDSSMRPGSEPGSASALGTPERRKGSLADVVDTLKQRKMEELIKNEPEEAPSIERLLSKDWKDKLLAMGSGNFGEIKGTPDSLAEKERQLMGMITQLSSLREQLLAAHEEQKKLAASQIEKQRQQMELAKQQQDQIARQQQQLLQQQHKINLLQQQIQQVQGQLPPLMIPVFPPDQRTLAAAAAQQGFLLPPGFNYKPGCSEPYPLQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGAKHSTVPQANLATGTLSPTSGQSEKNRSTPPPKPKDEGAQPLNLSSKPKASESKSPTSPASPQVPALKLGPGS--LKHSAPSSIGGPPSRLSSIDLLSSITSAGYLNDHEAVTKAFQEARKMKEQLKREEQVLDAKVAAVNSLSLNNGRSEKVRFMEKAALESLSQQL--KQSEESKFTHAMMDFGISGDSDGSPSVSDSRIFREARGRGSSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFTVGQQAQLPLSSAGVVYPGALSMAGMPSPQMPSEHSSMSSSPEPVPPTSQASY-FKEVEPRVKEELRMDDGNGDAYDDFDYEDDDG--DYGSDSENHITQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q59DN5-1", "uniprot_id": "Q59DN5_DROME", "id": "Q59DN5-1", "name": "", "aln": "-------------MKPPGEDQTNEKEHSDLGMIKQLQLIRNRILS--------------------------------------QAHYDSMT---------------DIDASAQQQQQLQNVQRLQHESCLQELHNHLSSQYGAVRFTAANPQHQNQQAVSVSSGNLMPFLPAFLQPPMPN-----AQQLLQLIPGHENAQSVPTHHHSHPQSEAFSTHKMALAPMWSTAAVAAAHIQAALAAAAVAAANNN---KNSSHFSNNTNIVGLATRGNELLNTDSDPQMEIGETRRGGNGGSCR-----SRPESPTYEN-----PPYEILSYSHNTPPESPHGR----------------TADCSKNFSPSPTDNLSIASVSEAQ--------------DSEMDAPLNLS-KPKGSPSSSPNSSSQRDH-----------CENLTPVVSSPPLSWHQG--------QPHYAEIELPLLKSHGRVWNSAVACSGGSRATRVSRDSVNSCGTNSERSAA--------------------LDPESLNSGQLGPVPASPSSQPLRQGNGHGHGGNHGHVHSKPHIKRPMNAFMVWAKDERRKILKACPDMHNSNISKILGARWKAMSNADKQPYYEEQSRLSKLHMEQHPDYRYRPRPKRTCIVDGKKMRISEYKVLMRNRRAEMRQLWCR----------TGGVSGGSGSLCADACP-----KGSGGSNSQVAVAAAAAVYHLQDMASSAASTAHGHDCGHTPPQQFFYPPESLSPSGFSSDEVELASQRELDD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. .. ..:: * .. * :.:. . : .* : .:*..: :: * *. . . : *:: .. . :::: : : .. : * : :*. : .. : * * :: : :: .: * :: **. . :**::*: :* ::: ::..:: :: : :.* : : :: : * * . . .:. * . .*: * :::. : :.. :. * .. . : * **. .::* :. ..* ***** *** * ..** *.:. . : .* . * : . * : . .: *: .. : .:. . *** . .. *: : .:. . :. :. *. . .:.: . :*: .:**********************:* *************:***:*:* :********:**** *:*::***:*:*******:*****:**.***.:***** **** : :* * .: ::.. ..* :.* .*..: .. : * : . . : .* . ::: :. . *..* .:: ", "identical_positions": 147, "similar_positions": 214, "identity": "18.68%" }, { "cls_id": "homologset.agr.RGD:620472", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C7N0-1", "uniprot_id": "RWDD3_RAT", "id": "P0C7N0-1", "name": "RWD domain-containing protein 3", "aln": "MAEEMRQELSALAAIFCGPHEWEMLSCSETDGAVFRIHTTAEGLAGEDVPLELAFHLPAGYPSCLPGISVNSERLTRAQCVTVKEKLLGEARRLLSEPMVHELVLWTQQNLRHILSQTETESSNGTCTLPESSTVDGGLWMTLLRLDHMRARTKYVKVVEKWASELRLTGRLMFMGKMILILLQGDRSNIKEYLILQKTSKVDVDSSGKKCKEKMISVLSETKVQTEHKRFLAFEVKEYSTLEELQKEFETAGLQELFSECVLGLVK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIL2-1", "uniprot_id": "RWDD3_MOUSE", "id": "Q8VIL2-1", "name": "RWD domain-containing protein 3", "aln": "MAEEVRQELSALAAIFCGPNEWEMLSCSETDGAVFRIHTTAEGLVGEDVPLELAFHLPVGYPLCLPGISVTSEHLTRAQCVTAKEKLLGEARKLVSEPMVHELVLWIQQNLRLVLSQPETVSSHEKCTLPESATGDDGPWMTLLRLDHMRARTKYVKAVEKWASELRLTGRLMFMGKLILILLQGDRSNIKEYLILQKTSKVDVDSSGKKCKEKMISVLSETKVQTEHKRFLAFEVKEYSTLEELQKEFGAAGLGELFSECVLGLVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3V2-1", "uniprot_id": "RWDD3_HUMAN", "id": "Q9Y3V2-1", "name": "RWD domain-containing protein 3", "aln": "MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDVDIPLELVFHLPVNYPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPETGSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIILILLQGDRNNLKEYLILQKTSKVDVDSSGKKCKEKMISVLFETKVQTEHKRFLAFEVKEYSALDELQKEFETAGLKKLFSEFVLALVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBV4-1", "uniprot_id": "RWDD3_DANRE", "id": "Q6PBV4-1", "name": "RWD domain-containing protein 3", "aln": "MSKEAFDELSVLSAIYCEQGEFEVLEESPEKGVVFRVHTLID--NNEKTPLDIIFHISPEYPNTPPDISISSNHLSRRQCHDLRRSLLDTAQSLPAEPMVHGLMLWLQENFSDLIK---TSSCHSAEVRPETTEET---WTALLHLDHMRSKAKYIKLIEKWTLELRLTGR-LFTGKLILILLQGTKENIKQYIHLLKSVKVDVDSSGKRCKEKMMSVLCEIPKPEDKIMMTTFEVKDILSLDDLRREFDLIGLNELYHQFVSSLT-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: :***.*:**:* *:*:*. * .*.***:** : . . **:: **:. ** *.**:.*::*:* ** :..** *. * :***** *:** *:*: ::. * * . . :: * :**:*****:::**:* :***: :****** :* **:******* :.*:*:*: * *: *********:*****:*** * :: : :****: :*::*::** ** :*: : * .*. ", "identical_positions": 114, "similar_positions": 74, "identity": "42.7%" }, { "cls_id": "homologset.agr.RGD:620473", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0X2-1", "uniprot_id": "SL9A5_RAT", "id": "Q9Z0X2-1", "name": "Sodium/hydrogen exchanger 5", "aln": "------------------------------------------------------------------------------------------MLRVALLLLPGLPLAGVGATEEP---------------------------------------------TQEPGPL-----------GEPP-GLALFRWQWHEVEAPYLVALWILVASLAKIVFHLSRKVTSLVPESCLLILLGLALGGIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGVALWGLQQAGLVAPRVQAGLLDFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTAVKYTMKTLASSAETVIFMLLGISAVDSSKWAWDSGLVLGTLFFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLRVKRSDYHKPTLNQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFVDQG----GHVLSSAGLTLPSMPSRNSVAETSVTNLLRESGSGACLDLQVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMKRRLES---FKSTKHNICFTKSKPRPRK------------TGHKKKDGVAN-PEATNGKPPRDLGFQDTAAVILTVESEEEEE---SESSETEKED--DEGIIFVARAT--------------------------------------------------------SEVLQEGKVSGSLEVCPSPRIIP----------------PSPTCAEKELPWKSG---------QGDLAVYVS----------------------------------SETTKIVPV------DMQTGWNQSISSLESLASPPCTQPPTLTRLP-----------------PHPLVPEEPQVPLDLSSDPR-------------------SSFAFPPS----------------LAKAGRSRSESSADIPQQQELQPLMGHKDHTHLSPGPANSHWCIQFNRGGRL---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RXE2-1", "uniprot_id": "SL9A5_MOUSE", "id": "B2RXE2-1", "name": "Sodium/hydrogen exchanger 5", "aln": "------------------------------------------------------------------------------------------MLSAALLLLPGLPLAGAGATEEP---------------------------------------------TQESGPL-----------GEPPPGLALFRWQWHEVEAPYLVALWILVASLAKIVFHLSRKVTSLVPESCLLILLGLVLGGIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGVALWGLQQAGLVAPRVQAGLLDFLLFGSLISAVDPVAVLAVFEEVHVNQTLFIIIFGESLLNDAVTVVLYKVCNSFVEMGSANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTAVKYTMKTLASCAETVIFMLLGISAVDSSKWAWDSGLVLGTLFFILFFRALGVVLQTWALNQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLRVKRSDYHKPTLNQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFVDQG----GHVLSSTGLTLPSMPSRNSVAETSVTNLLRESGSGACLDLQVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKASCGRHFISEDAQERQDKEIFQQNMKRRLES---FKSTKHNICFTKSKPRPRK------------TSHKKKDGVAN-PEATNGKPPRDLGFQDTAAVILTVESEEEEE---SDSSETEKED--DEGIIFVARAT--------------------------------------------------------SEVLQEGKVSGSLEVCPSPRIIP----------------PSPTCAEKELPWKSG---------QGDLAVYVS----------------------------------SETTKIVPV------DMQTGWNQSISSLESLASPPCTQPPTLTRLP-----------------PHPLVTEEPQVPIDLSSDPR-------------------SSFAFPPS----------------LAKAGRSRSESSADIPQQ-ELQPLMGHKDHTHLSPGTANSHWCIQFNRGGRL---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14940-1", "uniprot_id": "SL9A5_HUMAN", "id": "Q14940-1", "name": "Sodium/hydrogen exchanger 5", "aln": "------------------------------------------------------------------------------------------MLRAALSLLA-LPLA--GAAEEP---------------------------------------------TQKPESP-----------GEPPPGLELFRWQWHEVEAPYLVALWILVASLAKIVFHLSRKVTSLVPESCLLILLGLVLGGIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLVAPRVQAGLLDFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLASCAETVIFMLLGISAVDSSKWAWDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLKVKRSEHHKPTLNQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFVDQG----GHVLSSTGLTLPSMPSRNSVAETSVTNLLRESGSGACLDLQVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMKRRLES---FKSTKHNICFTKSKPRPRK------------TGRRKKDGVAN-AEATNGK-HRGLGFQDTAAVILTVESEEEEEE--SDSSETEKED--DEGIIFVARAT--------------------------------------------------------SEVLQEGKVSGSLEVCPSPRIIP----------------PSPTCAEKELPWKSG---------QGDLAVYVS----------------------------------SETTKIVPV------DMQTGWNQSISSLESLASPPCNQAPILTCLP-----------------PHPRGTEEPQVPLHLPSDPR-------------------SSFAFPPS----------------LAKAGRSRSESSADLPQQQELQPLMGHKDHTHLSPGTATSHWCIQFNRGSRL---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7YZY2-1", "uniprot_id": "B7YZY2_DROME", "id": "B7YZY2-1", "name": "Sodium/hydrogen exchanger", "aln": "MSIRTEQDYDSATPALAQQMNLARRACWRIKSYSSESLFKTYASVITDTSANEIDAEAPPPPRDKTKTRIEPQIAPAKRNSSCTSSDWRGMFSKRTLLICALALILGSAQARPNTSAVGVAPRKVSQDIVDAVTQLNLGQSAPIDAVDVGLDPTPSARVPRPEPLKSGDENAKGDEGHKMERYPLSSVDFARVKTPFIIGIWILSASIAKIGFHMTPKLHLIFPESCLLIVVGVVIGVVLYFCTDVAVSPLTPNTFFFYMLPPIILDAGYFMPNRLFFDNLGTILLMAVVGTIFNIATIGGSLYACGKMGIYGESETPGLMDVFLFASLISAVDPVAVLAVFEEIHVNEILYIVVFGESLLNDAVTVVMYHMMESYNEIGLDKIIAQDIASGVGSFFVVALGGTAIGIIWGFLTGLVTRFTDHVRVIEPIFIFVMAYLAYLNAEIFHMSGILAITFCGITMKNYVESNISQKSHTTVKYALKMLSSSAETIIFMFLGVATVNN-MHVWNTWFVVLTIAFCSVFRVIGVILLSALANRFRLHKLSRVDQFVMSYGGLRGAVAFALVLLVDENVVKQKNMFVTTTIAVIYFTVFLQGITIKPLVKILNVKRANKRKPTMNERIHERFMDHLMAGIEDIVGKTGNYNVRDKFKRFDNRFIRPLLIR-DLKGAEPKIIETYSKLTMRDAMEVMRRNPSTIGQMTGTESMSALFRNYTNNYIGGSPSLTNLDNTCSRNLDMAELDYNPSKKDLTDARIHHLLAEELKPYRRHRRLSYSRHAVDDRDLSTQVNYKMQMNFRRMFNDRKHHKRSKRGASNKEAKENVKQNHVSFHDFQQNGTTKQLTNGTESSSNHSRKKSYRKRHTHNSLNKYRRLEIAEECQQNPNEINVVGPSDDWDDGLTFTAKSSPDSDRANNNSLIAHIQNLPGFDASKARIVVQHYAPKADDNPDTDIESPEQAIGPTAAELILPWRRDRSYQSIVAEHPIPEEDRNLSRESDGERRVATPTATESQLPWKRQGDECTDAVQQNEFPAWASNKEYLAYNSPSATFLGGINKPKQPKSVIGLFRRESSSSKAGSVGVGSTGAMDSAASGSETMVVSMSSQPPNAPSTSIHNPRLDKRSQSISSSSLGAGAHQLGPEGHSGPFPVTASHRRNVRRGSMLELSGDTIPEESSYQHGHSKSLCEPADSDEWEGAPLSAAGGANSELLMRMSGREPLLPRPSNTPRAQIRRMNAGAVGGAGVSQAGRKNQVTKALLDYEDSETDSDENDDDEDEDFDSYDDENIVVTTFTTPATGRRPGSSPGSGSEANTATTTTTSIRLTRNNDESII", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *: *.* .* .* . .. . *. * :: .*::*:::.:*** **:*** **:: *: :.*******::*:.:* :: :. * * *.***:::****:**:*****.********:** *****::* * * :*:. : *: . .**:*.:**.*****************:***: *:*::*************:*:: :*: *:* :: * * .**.*:***:***:*:*:::.** .*.****.:**:***:::*::** ***.**: :*.***:*:**: *:***:***:**:*:***::* *:*.***:***:**:::*:. .*:: :*: *: * .**.:**:* : *:*** *.::**.****************:*:*.. * *: **:***.*::***::**:******* *.***:: :***:*:.:**: :**::*.:**:**: * : **::::**:::: **:* . . :* :.* :*.:***:..: :. *:: .: .:: *. * : :. .. **: :* * :* ** :****. * **: : * .** :.: . * : :* *::* ::. .* :*:. . .::* . :: * :: .:*. . .: :. * * ::: :* ** : .: . . .* *:*: *.*::: :*:: : . * : : : ** .:**.:*.:**** *.::..:.* *.::* .* *::. . * : : *::* * . .. * .* .* . *: :.:. * **: . * *: ** :.** :. : * * .:. :::: * : ..:..* ", "identical_positions": 338, "similar_positions": 314, "identity": "25.53%" }, { "cls_id": "homologset.agr.RGD:620474", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LYL9-1", "uniprot_id": "SOX9_RAT", "id": "F1LYL9-1", "name": "Transcription factor SOX-9", "aln": "MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLK--KESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS-VKNGQAEAEEATEQTHISPNAIFKALQ------------ADSPHSSSGMSEVHSPGEHSGQSQGPP-------------TPPTTPKTDVQAGKVDLKREGRPLAE-GGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP-NGHPGVPATHGQVSYTGSYGISSTAPTPATAGHVWMSKQQAPPPPPQQPPQAPQAPQAPPQ-QQAPPQPQQAPQQQ-QAHTLTTLS-SEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQISYSPFN---LPHYNPSYPTITRSQYDYTDHQN---SGSYYSHAAGQGSGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQT-HSPQHWEQ-PVYTQLTRP-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04887-1", "uniprot_id": "SOX9_MOUSE", "id": "Q04887-1", "name": "Transcription factor SOX-9", "aln": "MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLK--KESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS-VKNGQAEAEEATEQTHISPNAIFKALQ------------ADSPHSSSGMSEVHSPGEHSGQSQGPP-------------TPPTTPKTDVQAGKVDLKREGRPLAE-GGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP-NGHPGVPATHGQVTYTGSYGISSTAPTPATAGHVWMSKQQAPPPPPQQPPQAPQAPQAPPQ-QQAPPQQPQAPQQQ-QAHTLTTLS-SEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQISYSPFN---LPHYSPSYPPITRSQYDYADHQN---SGSYYSHAAGQGSGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQT-HSPQHWEQ-PVYTQLTRP-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48436-1", "uniprot_id": "SOX9_HUMAN", "id": "P48436-1", "name": "Transcription factor SOX-9", "aln": "MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLK--KESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS-VKNGQAEAEEATEQTHISPNAIFKALQ------------ADSPHSSSGMSEVHSPGEHSGQSQGPP-------------TPPTTPKTDVQPGKADLKREGRPLPE-GGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP-NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLS-SEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAYSPFN---LPHYSPSYPPITRSQYDYTDHQN---SSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQT-HSPQHWEQ-PVYTQLTRP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DFH2-1", "uniprot_id": "Q9DFH2_DANRE", "id": "Q9DFH2-1", "name": "", "aln": "MNLLDPYLKMTDEQEKCLSDAPSPSMSEDSAGSPCPSASGSDTENTRPAENSLLAADGTLGDFKKDEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNEVEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS-VKNGQSESEDGSEQTHISPNAIFKALQQ-----------ADSPASS--MGEVHSPSEHSGQSQGPP-------------TPPTTPKTDTQPGKADLKREARPLQENTGRPLSINFQDVDIGELSSDVI---ETFDVNEFDQYLPP-NGHQNAP-------YAGGY-------------AAWMTKPQNGSP---------------------------------QSSQLTPLNPAEPDQPRTTHIKTEQLSPSHYNEQQ-GSPQHISYGSFNVQHLQHYSTSFPSITRAQYDYSDSHQGG-ASSYYTHAGGQSSGLYSTFSYMSSSQRPMYTPIADSTGVPSIPQSNHSPQHWDQQPVYTQLSRP-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA17-1", "uniprot_id": "Q9VA17_DROME", "id": "Q9VA17-1", "name": "", "aln": "--------------------------MSDSSSSNCSKDRAKPVETLVLANYALKAEQKKAQGQGGRKEDER---ITTAVMKVLEGYDWNLVQASAKAP-TDRKKEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLRMTHKQEHPDYKYQPRRKKARVLPSQQSGEGGSPGPEMTLSATMGSSGKPRSSNSNGQRRAGKGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQSLIETGLDSPCSTASSMSSLTPPATPYNVAPSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQSAGVQSGAEGGGAGQEMDFLENINGYGGYTGSRVSYPAYSYPANGGHFATEEQQQQQALQASEALNYKPAAADIDPKEIDQYFMDQMLPMTQHHHPHHTHPLHHPLHHSPPLNSSASLSSACSSASSQQPVAEYYEHLGYSPAASSASQNPNFGPQQPYANGAASMTPTLGDPAPQQELQSQQQEQQHQNPSQHHLWGTYTYVNP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .**:.* *.. .. .*. : :: : :**: * ** :**:****.** ..:. :.::* *:**************** ::.*****:*:****:*****: *:: :*:**:* **:**: **::**********:*: * .* ..* .: ..:: .* : : *.. :: :.. *. .*:. ..... :. ::. : . :..*. . . . . :* .: .:.. . : : : . :*: * : : * . : :. :.*..:::. . .: : :: .: .. *:... . : . :. . ..** * . . :. :: . .*:* . *. : . . * . :. * :* : : :: ", "identical_positions": 96, "similar_positions": 160, "identity": "17.17%" }, { "cls_id": "homologset.agr.RGD:620475", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49146-1", "uniprot_id": "NPY2R_HUMAN", "id": "P49146-1", "name": "Neuropeptide Y receptor type 2", "aln": "MGPIGAEADENQTVEEMKVEQYGP-QTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LRW4-1", "uniprot_id": "A0ABK0LRW4_RAT", "id": "A0ABK0LRW4-1", "name": "Neuropeptide Y receptor type 2", "aln": "MGPLGAEADENQTV-EVKVELYGSGPTTPRGELPPDPEPELIDSTKLVEVQVVLILAYCSIILLGVVGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKQISFLIIGLAWGVSALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSVYGTVYSLSTLLILYVLPLGIISFSYTRIWSKLKNHVSPGAASDHYHQRRHKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSHVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSMTFKAKKNLEVKKNNGLTDSFSEATNV", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:********** *:*** **. ******* *************:******************:************************************************************************************************:***********:**************************************:********:********************************.*******:*******************************:**********************************************************:**********:**.* .***:*****", "identical_positions": 359, "similar_positions": 17, "identity": "93.98%" }, { "cls_id": "homologset.agr.RGD:620476", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTM9-1", "uniprot_id": "GRP4_MOUSE", "id": "Q8BTM9-1", "name": "RAS guanyl-releasing protein 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRKDIK-------------------------------------------------------RKSHQECSGKAGGRGRSRQARRHKTCPTPREISKVMASMNLGVLSESSCSEDELLEECIRCFDSAGSLRRGDHILKMVLTMHSWVLPSSELAARLLTSYQKAAKDAQELRQLQICYLVRYWLTHHHEAVHQEPQLEAVISRFWTTVAQEGNMAQRSLGDASSLLSP------------GGPGPPPPMSSPGLGKKRKVSLLFDHLETEELAQHLTYLEFRS--FQAITPQDLRGYVLQGSVRGCPALEGSVGLSNSVSRWVQVMVLSRPGPAQRAQVLDKFIRVAQRLHQLQNFNTLMAVTGGLCHSAISRLKDSHVHLSPDSTKALLELTELLSSHNNYAHYRRTWAGCTGFRLPVLGVHLKDLVSLYEAHPDRLPDG---------------RLHLPKLNSLYLRLQELMALQG--QHPPCSANEDLLH-----------LLTLSLDLFYTEDEIYELSYAREPRCPKSLPPSPFKAPVVVEWAQGVTPKPDSVTLGQHVEQLVESVFKN---------------YDPEGRGSISLEDFERLSGNFPFACHG----LHPPPRHGSGSFSREELTKYLLHASAICSKLG--LAFLHAFQEVTFRKPTFCHSCSGFL---------------WGVTKQGYRCRDCGLCCHRHCRDQVRVECKKRPETKGDPGPPGAPVPATSLPPAN-----------CGSEE-------------SLSYTLSPDPES---------------------------------------------------GCHLRHAWTQTES-----------------SHSSWEPEVVPCPARVLPSRASSKPSV---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R5I4-1", "uniprot_id": "GRP4_RAT", "id": "Q8R5I4-1", "name": "RAS guanyl-releasing protein 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRKDIK-------------------------------------------------------RKSHQECSGKAGGHGRPRQARRHKTCPTPREISKVMASLNLGVLSESSCSVDELLEECIRCFDSAGSLHRGDHILKMVLTMHSWVLPSSDLAARLLTSYQKAAKDARELRQLQICYLVRYWLTHHPEVVHQEPQLEAIINRFWTTVAQEGNMAQRSLGDASNLLSP------------GGPGPPPLMSSPGLGKKRKVSLLFDHLETEELAQHLTYLEFRS--FQAITPQDLRGYVLQGSVRGCPALEGSVGLSNSVSRWVQVMVLSRPGPAQRAQVLDKFIRVAQRLRQMQNFNTLMAVTGGLCHSAISRLKDSHVHLSPDSTKALLELTELLSSHNNYAYYRRTWASCTDFRLPVLGVHLKDLVSLYEAHPDRLPDG---------------RLHLPKLNSLYLRLQELAALQR--QHPPCSANEDLLH-----------LLTLSLDLFYTEDEIYELSYAREPRCPKSLPLSPFKAPVVVEWAHGVTPKPDSATLGQHVEQLVESVFKN---------------YDPEGHGSISLEDFEKLSANFPFACHG----LHPPPRHGSGSFSREELTKYLLHASAICSKLG--LAFLHAFQEVTFRKPTFCHSCNGFVS----------TGPLWGVTKRGYRCQDCGLCCHRHCRDQVRVECKKRPETKGDPGPPGAPGPATPLPPTG-----------CGSEE-------------GLSYTLSPHLES---------------------------------------------------GCHLHHAWTQTES-----------------SHSSWEPEMVPCPAPVLPSKASSKSSV---------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TDF6-1", "uniprot_id": "GRP4_HUMAN", "id": "Q8TDF6-1", "name": "RAS guanyl-releasing protein 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRKDSK-------------------------------------------------------RKSHQECTGKIGGRGRPRQVRRHKTCPSPREISKVMASMNLGLLSEGGCSEDELLEKCIQSFDSAGSLCHEDHMLNMVLAMHSWVLPSADLAARLLTSYQKATGDTQELRRLQICHLVRYWLMRHPEVMHQDPQLEEVIGRFWATVAREGNSAQRRLGDSSDLLSP------------GGPGPPLPMSSPGLGKKRKVSLLFDHLETGELAQHLTYLEFRS--FQAITPQDLRSYVLQGSVRGCPALEGSVGLSNSVSRWVQVMVLSRPGPLQRAQVLDKFIHVAQRLHQLQNFNTLMAVTGGLCHSAISRLKDSHAHLSPDSTKALLELTELLASHNNYARYRRTWAGCAGFRLPVLGVHLKDLVSLHEAQPDRLPDG---------------RLHLPKLNNLYLRLQELVALQG--QHPPCSANEDLLH-----------LLTLSLDLFYTEDEIYELSYAREPRCPKSLPPSPFNAPLVVEWAPGVTPKPDRVTLGRHVEQLVESVFKN---------------YDPEGRGTISQEDFERLSGNFPFACHG----LHPPPRQGRGSFSREELTGYLLRASAICSKLG--LAFLHTFHEVTFRKPTFCDSCSGFL---------------WGVTKQGYRCRECGLCCHKHCRDQVKVECKKRPGAKGDAGPPGAPVPSTPAPHAS-----------CGSEE-------------NHSYTLSLEPET---------------------------------------------------GCQLRHAWTQTES-----------------PHPSWETDTVPCPVMDPPSTASSKLDS---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLA4-1", "uniprot_id": "A0A8M2BLA4_DANRE", "id": "A0A8M2BLA4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGFDTMNRKESKS-----------------------------------------------------SRKSRQE-----GGIKSRRPVQRRMTCPSAQEISRALQSP-PAHASFRSASLDELILRCLHCFDSDGKLNRGTQLVSMTLMMHNWVVPSHIFAHKLLSLYKDCPAEKRGQRRPQICHFIRQWISQFRLMFEMDPLLEKAMGDLWALVSAEGTNSHHQLINTPYINPP------------VNISQTP---SP-LVKKRKVSLLFDHMEPDEMAEHLSYLEFKN--FCNVSFLDYRSYVVHGSVRDNPALERSVMLCNGVSQWVQLMILNRHTSQQRAEVFTKFIHVAQKLRSLQNFNTLMAVIGGLCHSSISRLKDTASLLSSDVTKTLSELTELLSSYSNYSNYRRVYSECTGFKVPILGVHLKDLISLNEALPDYLEDD---------------KINLGKLQHLYSNISDLLAIHD--CTPPFEANKDLLH-----------LLTLSLDLYYTEDEIYELSYAKEPKNPKIQPVAPVKPPVVAEWGSGVTPRLDPATISKHVKQMVDSIMKN---------------YDLNMDGYISLEEFEKIAANFPFSFC-----THESDRE--GEISREEITSYFMRGMSVCAKLGFNLHNLHNFHETTYKRPTFCDTCGGFL---------------WGVIKQGYHCKDCGVNCHKHCKDVVGMECLKRLQVNSSSCP-CTPGPVSGLHTKGNSWSEFSQSFQSGSEEEAFVFPNGNESEHSKGQTSSDSDAE---------------------------------------------------AATLSDRSTQTEPGVWTPVAKRKDRLHSQKQHPPLEKSAT-LPARVRGSSAPSSLLQEKMDELKLNKDKRKEPD----------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07866-1", "uniprot_id": "LTE1_YEAST", "id": "P07866-1", "name": "Guanine nucleotide exchange factor LTE1", "aln": "MEIFSQKDYYPTPSSNVISYESDCVSKPVNSADLPALIVHLSSPLEGVDYNASADFFLIYRNFITPQDLHDLLIYRFRWCIREITTNAAKAKRRRIGEVALVRTFVLLRHSILNYFVQDFLPNITLRLRLIEFLNDKHIEQYPKIISSCIINLKKNWVHCSKLVWENIELNEPDKLDFDAWLHYSLKDFTQLESLHKRGSRLSIYARQSFASPDFRNQSVLSLYKTSDVFRLPEKLQSSNSSKNQRSPSMLLFPDNTSNVYSKHRIAKEPSVDNESEDMSDSKQKISHLSKVTLVSTLMKGVDYPSSYAVDKIMPPTPAKKVEFILNSLYIPEDLNEQSGTLQGTSTTSSLDNNSNSNSRSNTSSMSVLHRSAIGLLAKWMKNHNRHDSSNDKKFMSAIKPANQKPEMDAFVKYVVSISSLNRKSSKEEEEEFLNSDSSKFDILSARTIDEVESLLHLQNQLIEKVQTHSNNNRGPTVNVDCERREHIHDIKILQQNSFKPSNDNFSAMDNLDLYQTVSSIAQSVISLTNTLNKQLQNNESNMQPSPSYDALQRRKVKSLTTAYYNKMHGSYSAESMRLFDKDNSSSRTDENGPQRLLFHETDKTNSEAITNMTPRRKNHSQSQKSMTSSPLKNVLPDLKESSPLNDSREDTESITYSYDSELSSSSPPRDTVTKKSRKVRNIVNNTDSPTLKTKTGFLNLREFTFEDTKSLDEKKSTIDGLEKNYDNKENQESEYESTKKLDNSLDASSEANNYDITTRKKHSSCNHKIKQAVVRPASGRISISRVQSIAITPTKELSIVDPEQNKSNSVIEEISEIEPLNLEYNKKSALYSDTSSTVISISTSKLFESAQNSPLKQTQNPQREFPNGTSVSETNRIRLSIAPTIESVVSDLNSITTGSTVETFETSRDLPVPHQRIINLREEYQRGNQDIISNTSSLHELKTIDLSDSNNDLESPSTHAKNNKYFFSPDDGSIDVASPMKNVEELKSKFLKNESETNSNISGSVLTMDDIDINDTSSARNTRRANSESAFTGSLNKKNLNEIANMLDDSINDDPITVALMKLEGTYEKIPEKPENTKSSDAIGIKTSKLADEVEMLNLNNLPSFQNSPAEKRKSLLIERRRQTIMNIPFTPDQSEKEGFTSSSPEKIDVSANVDVAVQAAQIQELIGQYRIHDSRLMISNNESHVPFILMYDSLSVAQQMTLIEKEILGEIDWKDLLDLKMKHEGPQVISWLQLLVRNETLSGIDLAISRFNLTVDWIISEILLTKSSKMKRNVIQRFIHVADHCRTFQNFNTLMEIILALSSSVVQKFTDAWRLIEPGDLLTWEELKKIPSLDRNYSTIRNLLNSVNPLVGCVPFIVVYLSDLSANAEKKDWILEDKVVNYNKFDTNVQIVKNFIQRVQWSKFYTFKVNHELLSKCVYISTLTQEEINELST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***. * .: .: : . . :. :: :.: * . * . .:* . . * . : :. : : . * : :. . . . * : . . . * : : .: . * ::. : . . . .. *.*** :.:: :. : : :*:::. * . * : .:.* :. * . :...: : : . . *. ::::. : : . :* .. :..: .*: : *: *.: : :. .::.: ..*.. : * :. ::.* : :.:* :: . .:..** . *: . ..::**. . : .. :. : * .: ::*::: ...:** * : . * .: .: .: .*: : . ..:. : :* ::: . *: : . : ..:.. : .: . : .: . : . . . . .. : . . ...*. * . * :: : . . . . : : ", "identical_positions": 47, "similar_positions": 224, "identity": "3.28%" }, { "cls_id": "homologset.agr.RGD:620477", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62623-1", "uniprot_id": "CDC20_RAT", "id": "Q62623-1", "name": "Cell division cycle protein 20 homolog", "aln": "-------MAQFVFESDLHSLLQLDAPIPNAPIARWQRKAKEATGPAP---SPMRAANRSHSAGRTPG---------------------------------------------RTPGKSNSKVQTTPSKP------------GGDRYIPQRSASQMEVASFLLSKENQPEDGGTPTKKEHQKAWARNLN------GFDVEEAKILRLSGKPQN---APEGYQNRLKVLYS-QKATPGSSRKACRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWNAGSGDILQLLQMEQPGDYISSVAWIKEGNYLAVGTSNAEVQLWDVQQQKRLRNMTS-HSARVSSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNIVNVWPSGPGESGWVPLQTFTQHQGAVKAVAWCPWQSNILATGGGTSDRHIRIWNVCSGACLSAVDVHSQVCSILWSP---------HYKELISGHGFAQNQLVIWKYPTMAKVAELKG-HTARVLSLTMSPDGATVASAAADETLRLWRCFE-----------------------------LDPALRREREKASTSKSSLIHQGIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJ66-1", "uniprot_id": "CDC20_MOUSE", "id": "Q9JJ66-1", "name": "Cell division cycle protein 20 homolog", "aln": "-------MAQFVFESDLHSLLQLDAPIPNAPVARWQRKAKEATGPAP---SPMRAANRSHSAGRTPG---------------------------------------------RTPGKSSSKVQTTPSKP------------GGDRFIPQRSASQMEVASFLLSKENQPEDRGTPTKKEHQKAWSLNLN------GFDVEEAKILRLSGKPQN---APEGYQNRLKVLYS-QKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWNAGSGDILQLLQMEQPGDYISSVAWIKEGNYLAVGTSNAEVQLWDVQQQKRLRNMTS-HSARVSSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNIVNVWPSGPGESGWAPLQTFTQHQGAVKAVAWCPWQSNILATGGGTSDRHIRIWNVCSGACLSAVDVHSQVCSILWSP---------HYKELISGHGFAQNQLVIWKYPTMAKVAELKG-HTARVLGLTMSPDGATVASAAADETLRLWRCFE-----------------------------MDPALRREREKASVAKSSLIHQGIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12834-1", "uniprot_id": "CDC20_HUMAN", "id": "Q12834-1", "name": "Cell division cycle protein 20 homolog", "aln": "-------MAQFAFESDLHSLLQLDAPIPNAPPARWQRKAKEAAGPAP---SPMRAANRSHSAGRTPG---------------------------------------------RTPGKSSSKVQTTPSKP------------GGDRYIPHRSAAQMEVASFLLSKENQPENSQTPTKKEHQKAWALNLN------GFDVEEAKILRLSGKPQN---APEGYQNRLKVLYS-QKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTS-HSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSP---------HYKELISGHGFAQNQLVIWKYPTMAKVAELKG-HTSRVLSLTMSPDGATVASAAADETLRLWRCFE-----------------------------LDPARRREREKASAAKSSLIHQGIR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IU39-1", "uniprot_id": "A0A0R4IU39_DANRE", "id": "A0A0R4IU39-1", "name": "", "aln": "-------MSQFGFENDIHNVLRLDMPITNAPMARWQRKASTSNSSSTNSISPNKSVNRSVSLSKTPS---------------------------------------------KTPGK-NGKTQNTPSKA------------GGDRYIPTRNNKQLDVASFLISKENEPVEESEPSTAPNQKAWSMSLN------GYDIEEAKILHLGGKPLY---APEGYQNNLKVLYS-QVPTP-VSVKKSRYISSYPERILDAPDIRNDFYLNLMDWGRQNVLAVGLANQVYLWDAGEGDIVLLKKMEDDNEYICSVSWSKDGNFLAIGTSDCKVELWDVQYQKRLRSMDG-HSARVGCLSWNDHILSSGSRSGLIHQHDVRVADHHIFTFGGHTQEVCGLTWSPDGRYLASGGNDNMVYIWPMTTG-SENQAIHALSEHQGAVKALAWCPWQPNILASGGGTSDRHIRIWNASSGSCISSLDTCSQVSSLVFAP---------NYKELVSGHGFAHDKVVIWKYPSFAKVTEHEG-HEARILNLALSPDGSTLASIAADETIRLWKCFE-----------------------------KEKDAAKKPKQASG---RIVQQSIR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P26309-1", "uniprot_id": "CDC20_YEAST", "id": "P26309-1", "name": "APC/C activator protein CDC20", "aln": "MPESSRDKGNAAISGNRSVLSIASPTKLNILSSDWSRNQGKVSKNSLKRSSSLNIRNSKRPSLQASANSIYSRPKITIGAPPLIRRDSSFFKDEFDAKKDKATFSAYSSRSYPTIGSESVVSQTSLSQPTTSREVDEQFTVAADRYIPILQGASQNKVDPETLHEALPPPNASPISHLRAQTKIVFKQNVAEACGLDMNKRILQYMPEPPKCSSLRQKSYIMKKRTHYSYQQEQKIPDLIKLRKINTNPERILDAPGFQDDFYLNLLSWSKKNVLAIALDTALYLWNATTGDVSLLTDFEN--TTICSVTWSDDDCHISIGKEDGNTEIWDVETMSLIRTMRSGLGVRIGSLSWLDTLIATGSRSGEIQINDVRIKQHIVSTWAEHTGEVCGLSYKSDGLQLASGGNDNTVMIWDTRTS----LPQFSKKTHTAAVKALSWCPYSPNILASGGGQTDKHIHFWNSITGARVGSINTGSQVSSLHWGQSHTSTNGGMMNKEIVATGGNPENAISVYNYETKFKVAEVVHAHEARICCSQLSPDGTTLATVGGDENLKFYKIFDPRCTGRSREDGLMDGMLGLIGKEGCRTNDKENRSKNSSEIHTRRPSSTSQYLIR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :..: : . . * : *.*: : *. . * . . ::.. * *. . *.: *:. ..**:** . . : .. :* * * . . :: : * *::: : : * :.* . :. ** * . * * : *:****** :::*:****:.*. ****:.* . :***.* **: * .:*: *.**:* .:. .:::*... :.::***: . :*.* . ..*:..*** . ::::***** *: :***: :* : * . *: ***** : .** ******** * :* .. . : . * .****::***:..*:**:*** :*:**::** :*: :.:::. ***.*: :. **::: * ..: : :::* : **:* * :*: :****:*:*: ..**.::::: *: : .. : : : **", "identical_positions": 138, "similar_positions": 173, "identity": "22.4%" }, { "cls_id": "homologset.agr.RGD:620478", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVR1-1", "uniprot_id": "INP5E_RAT", "id": "Q9WVR1-1", "name": "Phosphatidylinositol polyphosphate 5-phosphatase type IV", "aln": "--------------------------------MPSKSACLRHTE-APGQLEGRMLQGQLSNPEKKLIPTSASLPAADSQSSQTNSMPPLSMPAKPSNQNLQAKANLITPQPPIRPKLER-TLSLDDKGWRRRRFRGSQEDLTVQNGASPCRGSLQDSVAQSPAYSRPLPCLSTSLQEIPKPRRATGSEGGSPSL-WSDCLSGMISTSLDLLHREAASGGPH-SRLASLRATHTPPAMDLNIASSSLRTANKVDPEHTDYKLR-MQNRLVRAHSNLGPSRPRSPLAGDDHS----------------------------------------------------IHSARSSFSLLAPIRTKDIRSRSYLEGSLLASGALLGADELARYFPDRNMALFVATWNMQGQKELPASLDEFLLPTEADYTQDLYVIGVQEGCSDRREWETRLQETLGPQYVLLSSAAHGVLYMSLFIRRDLIWFCSEVEYSTVTTRIVSQIKTKGALGVSFTFFGTSFLFITSHFTSGDGKVAERLLDYNRTIQALALPRNVPDTNPYRSSAGDVTTRFDEVFWFGDFNFRLSGGRVAVEAFLK----QDPEVDVLALLQHDQLTREMKKGSIFKGFEEAEIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYKSRHKG-------------------DICPMKYSSCPGIKTSDHRPVYGLFRVKVRPGRDNIPLAAGKFDRELYLIGIKRRISKEIQ-RQEALKSQSSSAVCTVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JII1-1", "uniprot_id": "INP5E_MOUSE", "id": "Q9JII1-1", "name": "Phosphatidylinositol polyphosphate 5-phosphatase type IV", "aln": "--------------------------------MPSKSACLRHTE-APGQLEGRMLQGQPPNTEKKLIPTPGFLPASDSQGSETNPMPPFSIPAKTSNQNPQTKANLITPQPPIRPKLER-TLSLDDKGWRRRRFRGSQEDLTVQNGASPCRGSLQDSVAQSPAYSRPLPCLSTSLQEIPKSRRATGSEGGSPSL-WSDCLSGMISTSLDLLHRDAASGGPP-SRLASLHASHTPPAMDLSIASSSLRTANKVDPEHTDYKLR-MQTRLVRAHSNLGPSRPRSPLAGDDHS----------------------------------------------------IHSAR-SFSLLAPIRTKDIRSRSYLEGSLLASGALLGAEELARYFPDRNMALFVATWNMQGQKELPASLDEFLLPTEADYTQDLYVIGIQEGCSDRREWETRLQETLGPQYVLLSSAAHGVLYMSLFIRRDLIWFCSEVEYSTVTTRIVSQIKTKGALGVSFTFFGTSFLFITSHFTSGDGKVAERLLDYSRTIQALALPRNVPDTNPYRSSAGDVTTRFDEVFWFGDFNFRLSGGRVAVEAFLK----QKPEVDVLALLQHDQLTREMKKGSIFRGFEEAEIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYKSRHKG-------------------DICPMKYSSCPGIKTSDHRPVYGLFQVKVRPGRDNIPLAAGKFDRELYLIGIKRRISKEIQ-RQEALKSQSSSAVCTVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRR6-1", "uniprot_id": "INP5E_HUMAN", "id": "Q9NRR6-1", "name": "Phosphatidylinositol polyphosphate 5-phosphatase type IV", "aln": "--------------------------------MPSKAENLRPSEPAPQPPEGRTLQGQLPGAP----PAQRAGSPPDAPGSES-PALACSTPATPSGEDPPARAAPIAPRPPARPRLER-ALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSS-GGNPLSGVASSSPNLPHRDAAVAGSS-PRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYKLR-AQPLLVRAHSSLGPGRPRSPLACDDCS----------------------------------------------------LRSAKSSFSLLAPIRSKDVRSRSYLEGSLLASGALLGADELARYFPDRNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDRREWETRLQETLGPHYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLC----QGLVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKG-------------------DICPVSYSSCPGIKTSDHRPVYGLFRVKVRPGRDNIPLAAGKFDRELYLLGIKRRISKEIQ-RQQALQSQNSSTICSVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NEC2-1", "uniprot_id": "A0A8M1NEC2_DANRE", "id": "A0A8M1NEC2-1", "name": "Phosphatidylinositol polyphosphate 5-phosphatase type IV", "aln": "--------------------------------MSEHGDSIVPFN--PTDLR----SGEPATKTDITVLSVDLRTEKSHNEELRDIKKPYDGPKVLQDEHSLYQPRPPSLPKPMGLGMGGKNLSFDEK-VRGRRLRNSQESLTDPGETGSSTDSLKDVASANGQTLASRRPLDLQHMEMPPFRIRTGS------------LSETDVSPHDLCDPNKERMKPSRIVLSPLQPTGTYPLLENSTASASLRTTNRIDRDCLDYGVVGRRGRSERLHRNLSDSRLLDTMVSDNTS----------------------------------------------------VHSMKSTYSVLNPIRPRDVRNRSFLEGSVLGNGALLGAEELDRYFPERRLGIYIATWNMQGEKGLPYNLDDLLLPTDTDFAQDVYVIGVQEGCPDRREWEIRLQETLGPYYVMLYAAAHGVLYLTVFVRRDLIWFCSEVEHATVTTRIISQIKTKGAVGIGFTFFGTSFLFVTSHFTSGDSKVYERILDYNKIIEALALPRNLPDTNPYRSTTSDVTTRFDEVFWFGDFNFRLNKARGDVEAILN----QGVGVDMSPLLQHDQLTREMKEGSIFKGFQEASIHFPPTYKFDIGCDVYDTTTKQRTPSYTDRILYRNRQAD-------------------DIRVIKYTSCSSIKTSDHRPVIGMFQVKLRPGRDNIPLGAGLFDRSLYLEGIRRRITRELKKREAVMKNQNNSTVCSIS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTW2-1", "uniprot_id": "INP5E_DROME", "id": "Q9VTW2-1", "name": "Inositol polyphosphate 5-phosphatase E", "aln": "MQHSSAGSEERITSSTSSPRSGHKTASSLFGLLSKRPSKVEPHPVTPESPRLQQRPVSACGQYDVSFAKCNADTSANHVNNNGSTLKSQTLPLEKSHSGLISFHRRAKPSSSKGKNHSHRHSTDAGSQSDGGADVVMRRKSPKHRSPNHNRFSHQFSLCCKAEKKPMTPPVTVRYNSIPDSNSVLRRDNLSLSWSMVDNNSGSLHSSEGSSHRPRPSSECASAPESPVASKTFFAHCSPAAASASVARSESLQNRSPIRPMAVSACRSRLRLKLYPPGQELPPLQAATEPGDIKRATTPQHMSSPNIATQPDGIEHIEEQPGVRFMSHENMTLQRQGSGSNLARQTLMAAHALNLIPADNARERSYLDG-RLGSTSLLGPSELSRVLPQKEITVFVGTWNMNG-HSPPKQLNDFVLPANVEHVPDIVVMGTQESTPDRFEWEVTIQETLGPSHVLFHATTLGTLHLAVYMRRDLIWYCSVPEDASMSVRTGSAFRTKGAVAISFCLFGTSMLFVTSHLTAHQQKVKERVSDVKRIINALDLPRNLPNQ---RHKNKDVTQNFDNVFWCGDLNFRLGEPREKLLEWIQNTKFPLPSHLPHGYMHTDQLTSVLADGAAFRGFMEANITFPPTYKYDPGSQNFDTSSKQRAPAYTDRILYKYRQMQGLVIRRQTLVPGVSTPTQPHVQCLLYDSVPSITTSDHKPVWALFRTLIRAGTDAIPLAAGLFSRDIYLEGMRRRLNNQYS---------GASAVCVLQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..: : * . . . . . . * . . . : . :.. .. * : : .:* . * :. . . ..: . . . ** *: :: :: : .: .: . :. : * * . : *.**:*:* *.. :***..** * :*::.: :::.****:* : * .*::::**::.:.. *: *:* **. .** *** :****** :*:: ::: *.*::::::******:** * ::::.* * ::****:.:.* :****:**:***:*: : ** **: * .: ::** ****:*: * . *** .**:*** **:****. * : : :: *** : .*: *:** *..* * *:**:* * : :*:::***:*:****:**: *: .: : * * ..*.****:** .:*:. :*.* * ***.** *.*.:** *::**:..: . . *::* :.", "identical_positions": 159, "similar_positions": 181, "identity": "20.89%" }, { "cls_id": "homologset.agr.RGD:620479", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97536-1", "uniprot_id": "CAND1_RAT", "id": "P97536-1", "name": "Cullin-associated NEDD8-dissociated protein 1", "aln": "MASASYH-ISNLLEKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPASSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTIINICLKYLTYDPNYNYDDEDEDE-NAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCLDAVVSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDAMEQGETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRPLDQ---PSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMGQIICNLGDNLGPDLSNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILASFLRKNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHVSQMAISFLTTLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLRMLTGPVY-------SQSTALT-------HKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSIRLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKEIISSASVVG-----LKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKTLEDPDLNVRRVALVTFNSAAHNKPSLIRDLLDSVLPHLYNETKVRKELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFLMLVRLSTLCPSAVLQRLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLTIPEAEKSPLMSEFQSQISSNPELAAIFESIQKD--SSSTNLESMDTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VP6-1", "uniprot_id": "CAND1_HUMAN", "id": "Q86VP6-1", "name": "Cullin-associated NEDD8-dissociated protein 1", "aln": "MASASYH-ISNLLEKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPASSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTIINICLKYLTYDPNYNYDDEDEDE-NAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCLDAVVSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDAMEQGETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRPLDQ---PSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMGQIICNLGDNLGSDLPNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILASFLRKNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHVSQMAISFLTTLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLRMLTGPVY-------SQSTALT-------HKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSIRLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKEIISSASVVG-----LKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKTLEDPDLNVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFLMLVRLSTLCPSAVLQRLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLTIPEAEKSPLMSEFQSQISSNPELAAIFESIQKD--SSSTNLESMDTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZQ38-1", "uniprot_id": "CAND1_MOUSE", "id": "Q6ZQ38-1", "name": "Cullin-associated NEDD8-dissociated protein 1", "aln": "MASASYH-ISNLLEKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILRLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPASSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTIINICLKYLTYDPNYNYDDEDEDE-NAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCLDAVVSTRHEMLPEFYKTVSPALIARFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDAMEQGDTPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRPLDQ---PSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMGQIICNLGDNLGPDLSNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILASFLRKNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHVSQMAISFLTTLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLRMLTGPVY-------SQSTALT-------HKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSIRLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKEIISSASVAG-----LKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKTLEDPDLNVRRVALVTFNSAAHNKPSLIRDLLDSVLPHLYNETKVRKELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFLMLVRLSTLCPSAVLQRLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLTIPEAEKSPLMSEFQSQISSNPELAAIFESIQKD--SSSTNLESMDTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VKY2-1", "uniprot_id": "CAND1_DROME", "id": "Q9VKY2-1", "name": "Cullin-associated NEDD8-dissociated protein 1", "aln": "MASHQYHQIANLLEKMTSTDKDFRFMATNDLMTELQKDSIILDDESEKKVVRMVLKLLEDKNGEVQNLAVKCLGPLVNKVKEIQVETIVDSLCANMMSNTEQLRDISSIGLKTVIAELPQSS--NSLAPNVCQRITGKLSTAIEK-EDVSVKLESLDILADLLSRFGEFLVPFHSTILKALMPQLASSRQAVRKRTIVALSFLLIQANSNAYNGVIDHLLDGLENPPNPAAIRTYIQCLASICRQAGHRLCNHIDRSMLLLSQYSQRDDDELREFCLQACEAFVMRCPDAINPHIPMILELCLNYITYDPNYNYETDDGDTGNAMDTE---DDEYVDSEEYSDDDDMSWKVRRAAAKCLEVLISTRQELVEDFYRSLSPALIARFKEREENVKSDIFHAYVALLKNTRLTDDVANDHDSMDQVSGPTSLLIEQLPLIVKAIQPLMREKSMKTRQDCFLLLRELLNSLPGALGPYLDSIVPGISYSLNDKSSTSNMKIESLGFLYSLLQGHPPHVFHPHIPLLVPLVVTSVFDPFYKIATEALLVLQQLVKVIRPLEPNAAKSDFDAPSFVGQVYSCTLQKLKVTDVDQEVKERAIACMGQIIANMGDMLQNELAVCLPIFMERLKNEVTRLSSVKALTLIAASSLRIDLTPILHDVLPALGTFLRKNHRALKLHSLDLINKIVINYSSNFEANLLQTAIVEIPPLISDSDLHVAQYSLTLLSTVARRQPQALVGIHEQFLRSVLILVRSPLLQGSALNCTLELFQALVQTQLSGLDYHSLVSKLMAPVLGGNGDVKSRATAGAPSEVVQLHKQAYHSSAKCIAALTQQCPQVATPLATKLITDLQ--KRNDTEIIFCLLTIGEIGRHFDLSSIQVLPQTIIECFGATSEDVKAAASHALGAVSVGSLQTYLPLILHEIEVQPKRQYLLLHSLKEVISSLSVSPSGLAQLLPSVPSIWDQLFKHCECSEEGSRNVVAECLGKLVLVNPDELLPQLQQALRSESATMRTVVVSSVKFTISDQPQPIDVLLKQNIGEFLFALRDPEPQVRRVALVAFNSAVHNKPSLVRDLLPTLLPWLYSETKVKSELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLEQGLDRVDVMQFLDHVQAGLCDHYDIKMLTYLMTARLAILCPDKVLLRLDQFIQQLRDTCTHKVKANSVKQEYEKQDELKRSALRAVSALSQIPKANKNQQLVDFLKSIKETPELNKIFEYIQKDSITGSSDIIVMDQS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** .** *:********:********************* ***:**:***:*:*:*********************.**** *******:**:**:*:.***************.*** :* .:**.***::***:*::** * *****:**:***:**:*** * :** **.:**..*:***:*.* *******:**..*::.... .: .:*:***. *.: . :: ******:*:*.******: ::::: : *: ::.: *******:*:** *:** ***. : **:. *:::**:*:********: :* * ****:: **: ..:********************:.::***:*:: :**:::*****:**********:*:****::***:** .:. * *:*:* . * ::* .*:* ****:: *:***:**** ** :* **:* ***** :: :**** :*******:**:**::*. ** :* .*.*:*****: *** **:.* ******::***** **********: *.***..:: ::::**:::**.:*:*********:******.*:** * :*. * **:******:***::********.*.*:*** *:* : :* *.:*****:***** :*. :: :: ***..: * ::::.: *:*****:**:**:* ::::*:*:*: *.:* * .:*..:: *********.**.. *::***** * ..*.* .*: * .** *::** : ***:*:* ***:****: **: ...:. ::* *:: : .*: ::.**::**:*:*:***. * ..*:*.*.:.**:**:***:***::***.* ***::*:** **************:*** ** * * * .** *:*****:***:***********.*::*: ***:*: * * *: *: **::*******:***** ***: **:** :*.**: :*******:****.******:**** ::** **.****:.*********************************:. ***:*:::**:**: ** *********:** .**: ***. ** ***:::: ** *** **********:**********:***:** **:*:*. : :* ..*...*** *** **** :.*::: ** *", "identical_positions": 733, "similar_positions": 330, "identity": "58.36%" }, { "cls_id": "homologset.agr.RGD:62048", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01320-1", "uniprot_id": "TOP2A_MOUSE", "id": "Q01320-1", "name": "DNA topoisomerase 2-alpha", "aln": "MELSPLQPVNENMLMNK-KKNEDGKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVG-INYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNVISIWNNGKGIPVVEHKVEKIYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGRAGDMELKPFS-GEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNSLPVKGFRSYVDLYLKDKVD----ETGNS-------LKVIHEQVNPRWEVCLTMSERGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQIQLNKKCSAVKHTKIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHR-FLEEFITPIVKVSKNK---QEIAFYSLPEFEEWKSSTPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQVDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQSTSYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLRFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLPMLPSYKNFKGTIEELASNQYVINGEVAILDSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPSLITDYREYHTDTTVKFVIKMT--EEKLAEAERVGLHKVFKLQSSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIENKPKKELIKVLIQRGYD--SDPVKAWK-----EAQQKVPDEEENEESD--TETSTSDSAAEAGP-----------TFNYLLDMPLWYLTKEKKDELCKQRNEKEQELNTLKQKSPSDLWKEDLAVFIEELEVVEAKEKQDEQVGLPGKAGKAKGKKAQMCA-DVLPSPRGKRVIPQVTVEMKAEAE--KKIRKKIKSENVEGTPAEDGAEPGSLRQRIEKKQKKEPG--AKKQTTLPFKPVKKGRKKNPWSDSESDVSSNESNVDVPPRQKEQRSAAAKAKFTVDLDSDEDFSGLDEKDEDEDFLPLDATPPKAKIPPKNTKKALKTQGSSMSVVDLESD-VKDSVPASPGVPAADFPAETEQSKPS-KKTVGVKKTATKSQSSVSTAGTKKRAAPKGTKSDSALSARVSEKPAPAKAKNSRKRKPSSSDSSDSDFERAISKGATSKKAKGEEQDFPVDLEDTIAPRAKSDRARKPIKYLEESDDDDDLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41516-1", "uniprot_id": "TOP2A_RAT", "id": "P41516-1", "name": "DNA topoisomerase 2-alpha", "aln": "MELSPLQPVNENMLLNK-KKNEDGKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVG-INYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTMMR-NNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGRAGDMELKPFS-GEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNRLPVKGFRSYVDMYLKDKVD----ETGNA-------LKVVHEQVNPRWEVCLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKADQVKNHMWIFGNAVIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQIQLNKKCSAVKHNRIKGIPKLDDANDAGSRNSAECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHR-FLEEFITPIVKVSKNK---QEIAFYSLPEFEEWKSTNPNHKKWKVKYYKGLGTSTSKEAKEYFANMKRHRIQFKYSGPEDDAAISLAFSKKQVDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTMYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPSKDDHTLRFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLPMLPSYKNYKGTIEELASNQYVINGEVAILNSTTIEITELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVIKMT--EEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESSKLNNQARFILEKIDGKIVIENKPKKELIKVLIQRGYD--SDPVKAWK-----EAQQKVPEEEENEENEE-SESESTSPAAESGP-----------TFNYLLDMPLWYLTKEKKDELCKQRDEKEQELNTLKKKTPSDLWKEDLAAFVEELEVVEAKEKQDEQVGLPGKGVKAKGKKAQIS--EVLPSPVGKRVIPQVTMEMRAEAE--KKIRRKIKSENVEGTPAEDGAEPG-LRQRLEKRQKREPGTRAKKQTTLPFKPIKKAQKQNPWSDSESDMSSNESNFDVPPREKEPRIAATKAKFTADLDSDDDFSGLDEKDEDEDFFPLDDTPPKTKMPPKNTKKALKPQKSSTS-VDLESD-GKDSVPASPGASAADVPAETEPSKPSSKQTVGVKRTITKGQSLTSTAGTKKRAVPKETKSDSALNAHVSKKPAPAKAKNSRKRMPSSSDSSDSEFEKAISKGATSKKLKGEERDFHVDLDDTVAPRAKSGRARKPIKYLEESDDD--LF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11388-1", "uniprot_id": "TOP2A_HUMAN", "id": "P11388-1", "name": "DNA topoisomerase 2-alpha", "aln": "MEVSPLQPVNENMQVNKIKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVG-INYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGRAGEMELKPFN-GEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLD----ETGNS-------LKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQVQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHR-FLEEFITPIVKVSKNK---QEMAFYSLPEFEEWKSSTPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLPMLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVVKMT--EEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYD--SDPVKAWK-----EAQQKVPDEEENEESDNEKETEKSDSVTDSGP-----------TFNYLLDMPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGLPGKGGKAKGKKTQMA--EVLPSPRGQRVIPRITIEMKAEAE--KKNKKKIKNENTEGSPQEDGVELEGLKQRLEKKQKREPGTKTKKQTTLAFKPIKKGKKRNPWSDSESDRSSDESNFDVPPRETEPRRAATKTKFTMDLDSDEDFSDFDEKTDDEDFVPSDASPPKTKTSPKLSNKELKPQKSVVS--DLEADDVKGSVPLSSSPPATHFPDETEITNPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAPKGTKRDPALNSGVSQKPDPAKTKNRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGESDDFHMDFDSAVAPRAKSVRAKKPIKYLEESDEDD-LF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15348-1", "uniprot_id": "TOP2_DROME", "id": "P15348-1", "name": "DNA topoisomerase 2", "aln": "--------------------MENGNKALSIEQMYQKKSQLEHILLRPDSYIGSVEFTKELMWVYDNSQNRMVQKEISFVPGLYKIFDEILVNAADNKQRDKSMNTIKIDIDPERNMVSVWNNGQGIPVTMHKEQKMYVPTMIFGHLLTSSNYNDDEKKVTGGRNGYGAKLCNIFSTSFTVETATREYKKSFKQTWGNNMGKASDVQIKDFN-GTDYTRITFSPDLAKFKMDRLDEDIVALMSRRAYDVAASSKGVSVFLNGNKLGVRNFKDYIDLHIKNTDD----DSGPP-------IKIVHEVANERWEVACCPSDRGFQQVSFVNSIATYKGGRHVDHVVDNLIKQLLEVLKKKNKGGINIKPFQVRNHLWVFVNCLIENPTFDSQTKENMTLQQKGFGSKCTLSEKFINNMSKSGIVESVLAWAKFKAQNDIAKTG-GRKSSKIKGIPKLEDANEAGGKNSIKCTLILTEGDSAKSLAVSGLGVIGRDLYGVFPLRGKLLNVREANFKQLSENAEINNLCKIIGLQYKKKYLTEDDLKTLRYGKVMIMTDQDQDGSHIKGLLINFIHTNWPELLRLP-FLEEFITPIVKATKKN---EELSFYSLPEFEEWKNDTANHHTYNIKYYKGLGTSTSKEAKEYFQDMDRHRILFKYDGSVDDESIVMAFSKKHIESRKVWLTNHMDEVKRRKELGLPERYLYTKGTKSITYADFINLELVLFSNADNERSIPSLVDGLKPGQRKVMFTCFKRNDKREVKVAQLSGSVAEMSAYHHGEVSLQMTIVNLAQNFVGANNINLLEPRGQFGTRLSGGKDCASARYIFTIMSPLTRLIYHPLDDPLLDYQVDDGQKIEPLWYLPIIPMVLVNGAEGIGTGWSTKISNYNPREIMKNLRKMINGQEPSVMHPWYKNFLGRMEYVSDGRYIQTGNIQILSGNRLEISELPVGVWTQNYKENVLEPLSNGTEKVKGIISEYREYHTDTTVRFVISFAPGEFERIHAEEGGFYRVFKLTTTLSTNQMHAFDQNNCLRRFPTAIDILKEYYKLRREYYARRRDFLVGQLTAQADRLSDQARFILEKCEKKLVVENKQRKAMCDELLKRGYR--PDPVKEWQRRIKMEDAEQADEEDEEEEEAAPSVSSKAKKEKEVDPEKAFKKLTDVKKFDYLLGMSMWMLTEEKKNELLKQRDTKLSELESLRKKTPEMLWLDDLDALESKLNEVEEKERAEEQGINLKTAKALKGQKSASAKGRKVKSMGGGAGAGDVFPDPDGEPVEFKITEEIIKKMAAAAKVAQAAKEPKKPKEPKEPKVKKEPK--GKQIKAEPDASGDEVDEFDAMVEGGSKTSPKAKKAVVKKEPGEKKPRQKKENGGGLKQSKIDFSKAKAKKSDDD---VEEVTPRAERPGRRQASKKIDYSSLFS--DEEED--GGNVGSDDDGNASDDDSP--------------KRPAKRGREDESSGGAKKKAPPK------------------------KRRAVIESDDDDIEID--------------EDDDDDSDFNC----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06786-1", "uniprot_id": "TOP2_YEAST", "id": "P06786-1", "name": "DNA topoisomerase 2", "aln": "----------------------MSTEPVSASDKYQKISQLEHILKRPDTYIGSVETQEQLQWIYDEETDCMIEKNVTIVPGLFKIFDEILVNAADNKVRDPSMKRIDVNIHAEEHTIEVKNDGKGIPIEIHNKENIYIPEMIFGHLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTEFILETADLNVGQKYVQKWENNMSICHPPKITSYKKGPSYTKVTFKPDLTRFGMKELDNDILGVMRRRVYDINGSVRDINVYLNGKSLKIRNFKNYVELYLKSLEKKRQLDNGEDGAAKSDIPTILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKKKKK--SVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIMKTDLATRMFEIADANEENALKKSD-GTRKSRITNYPKLEDANKAGTKEGYKCTLVLTEGDSALSLAVAGLAVVGRDYYGCYPLRGKMLNVREASADQILKNAEIQAIKKIMGLQHRKKYEDT---KSLRYGHLMIMTDQDHDGSHIKGLIINFLESSFPGLLDIQGFLLEFITPIIKVSITKPTKNTIAFYNMPDYEKWREEESHKFTWKQKYYKGLGTSLAQEVREYFSNLDRHLKIFHSLQGNDKDYIDLAFSKKKADDRKEWLRQYEPG------------TVLDPTLKEIPISDFINKELILFSLADNIRSIPNVLDGFKPGQRKVLYGCFKKNLKSELKVAQLAPYVSECTAYHHGEQSLAQTIIGLAQNFVGSNNIYLLLPNGAFGTRATGGKDAAAARYIYTELNKLTRKIFHPADDPLYKYIQEDEKTVEPEWYLPILPMILVNGAEGIGTGWSTYIPPFNPLEIIKNIRHLMNDEELEQMHPWFRGWTGTIEEIEPLRYRMYGRIEQIGDNVLEITELPARTWTSTIKEYLLLGLS-GNDKIKPWIKDMEEQHDDN-IKFIITLS--PEEMAKTRKIGFYERFKLISPISLMNMVAFDPHGKIKKYNSVNEILSEFYYVRLEYYQKRKDHMSERLQWEVEKYSFQVKFIKMIIEKELTVTNKPRNAIIQELENLGFPRFNKEGKPYYGSPNDEIAEQINDVKGATSDEEDEESSHEDTENVINGPEELYG-----TYEYLLGMRIWSLTKERYQKLLKQKQEKETELENLLKLSAKDIWNTDLKAFEVGYQEFLQRDAEARGGNVPNKGSKTKGK-----------------GKRKLVDDEDYDPS--KKNKKSTARKGKKIKLEDKNFERILLEQKLVTKSKAPTK--IKKEKTPSVSETKTEEEENAPSSTSSSSIFDIKKEDKDEGELSKISNKFKKISTIFDKMGSTSATSKENTPEQDDVATKKNQTTAKKTAVKPKLAKKPVRKQQKVVELSGESDLEILDSYTDREDSNKDEDD-----------AIPQRSRRQRSSRAASVPKK----------------------------SYVETLELSDDSFIEDDEE------------ENQGSDVSFNEED--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: :* . *** :****** ***:****** : *:**:. . : :::::****:************** ** .*. * : : .: :.: *:*:***: *: :::*:* :***:*******:***********************.* :*** : : : *.* :**. . ::. :. * .** :**.***::* *. **:**:.:* **.**: .* :.:.*:***: * ::.*:.*:::::*. . :.* .:::* * ****. *: .***:******** ** **:::.*:::.:: :::***:* :*. *::*::::* *.:****:* *****::* : *.*** * :. ::*: .:. :: .. : : : *. . : .:*.. ***:***.** ::. :***:******* :***:**.*:*** ** :*****:******. .*: :****: : **:***::*:* *:****::*******:********:***:. .:* ** ** ******:*.: .: : ::**.:*::*:*:. .:: .:: ********* ::*.:*** ::.** *: *. * :*****: :.** ** :. : :. **** **:*** :** ****.::**:*******:: ***:* * *:*****: *:* ::***** ** **:.*******:**: ** * * **** ****.*:.***:* :. *:* :: . ** : :* : :** **:**:**:*:*********** *. :: *:::*:*::::.:* * * ::.: * :* : :* *.: :... :**:*** .**.. ** :* : *.:* *.: .* * *. ::*::.:: : .:.. *::. *** :.:: .* ** . :::: :. :** ::: :* :** *:: : * : : . *.:** : :: : ** :: : . * : *: . * : * :: : . .. :. . . .::***.* :* **:*: ::* : :: * **:.* : :.. :* ** .: : . :: . .. **: : : :. * .. . : * .: : * . *: .: . . : :. . *. . .: . * . : . : ::* . . :: . . . : . : : . :. : : :. :: .** . **.. : : *. . .:: ", "identical_positions": 470, "similar_positions": 446, "identity": "29.84%" }, { "cls_id": "homologset.agr.RGD:620480", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0L4-1", "uniprot_id": "CAND2_RAT", "id": "Q9R0L4-1", "name": "Cullin-associated NEDD8-dissociated protein 2", "aln": "-MSTGAFYISSLLEKMTSSDKDFSPKSLGGSRVLDPLPWLQILAAITDWISGDRTQDLALPRFMATSDLMSELQKDSIQLDEDSERKVVRTLLRLLEDRSGEVQNLAVKCLGPLVGKVKEYQVENIVDTLCANMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLAISVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGAPLGTFHASLLHCLLPQLSSPRLAVRKRTVVALGHLAAACSTDLFVELADHLVDRLPGPRAPASPAAIRTLIQCLGSVGRQAGHRLGAHLDRLMPLVEEFCNLDDDELRESCLQAFEAFLRKCPKEMDPHVPNVTSLCLQYMKHDPNYNHDSD-EEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCMAALISSRPDLLPDFHCTLAPALIRCFKEREENVKADIFGAYIMLLRHTRPPKGWLEAVEEPTQTGRNLNMLRAQVPLVMKALQRQLKDRNVRTRQGCFNLFTELAGVLPGCLAEHMTVLVSGIVFSLADYSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPTLLPPVMACVADPFYKVAAEALLVLQELVRTLWPLDR---PRLLDPEPYVGEMSTATLARLRATDLDQEVKERAISCVGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAVKALTLVAVSPLRLDLQPILAEALPILASFLRKNQRALRLATLAALDALAQSQGLGLPPPAVRSVLAELPALVSENDMHVAQLAVDFLTTVTQTQPASLVEVSGPVLEELLQLLHSPLLPAGVLAATEGFLQALVGTRPPCVEYSELISLLTAPVYN-------QVGDGGP----GLHKQVFHSLARCVAALSAACPQEAAGTASRLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGPQRELKTVLLEALGSPSEDVRAAAAYALGRVGAGNLPDFLPFLLAQIEAQPRRQYLLLHALREALG--AAQPD---NLKPYVEDVWALLFQRCESPEEGTRCVVAECIGKLVFVNPPFLLPRFRKQLAAGQPYTRSTVITAVKFLISDQPHSIDPLLKSFIAEFMESLQDPDLNVRRATLTFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMLARLAALCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQELEKQDELKRSAMRAVAALMTNPEVRKSPSVADFSTQIRSNPELATLFESIQKDTASGPS-MDSMELS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQ73-1", "uniprot_id": "CAND2_MOUSE", "id": "Q6ZQ73-1", "name": "Cullin-associated NEDD8-dissociated protein 2", "aln": "-MSTGAFYISSLLEKMTSSDKDF--------------------------------------RFMATSDLMSELQKDSIQLDEDSERKVVRTLLRLLEDRSGEVQNLAVKCLGPLVGKVKEYQVENIVDTLCANMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLAINVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGAPLGTFHASLLHCLLPQLSSPRLAVRKRTVVALGHLAAACSTDLFVELADHLVDRLPGPRAPASPAAIRTLIQCLGSVGRQAGHRLGAHLDRLVPMVEEFCNLDDDELRESCLQAFEAFLRKCPKEMDPHVPNVTSLCLQYMKHDPNYDHDSD-DEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCMAALISSRPDLLPDFHCTLAPALIRRFKEREENVKADIFGAYIMLLRHTRPPKGWLEAVEEPTQTGRNLNMLRAQVPLVIKALQRQLKDRNVRTRQGCFNLFTELAGVLPGSLAEHMAVLVSGIVFSLADYSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPTLLPPVMACVADPFYKVAAEALLVLQELVRTLWPLDR---PRLLDPEPYVGEMSTATLARLRATDLDQEVKERAISCVGHLVGHLGDRLGDDLEPTLMLLLDRLRNEITRLPAVKALTLVAMSPLRLDLQPILAEALPILASFLRKNQRALRLATLAALDALAQSQGLGLPPPAVRTVLTELPALVSENDMHVAQLAVDFLTTVTQTQPSSLVEVSGPVLGELLQLLHSPLLPAGVLAATEGFLQALVGTRPPCVEYSELISLLTAPVYN-------QVGDGGP----GLHKQVFHSLARCVAALSAACPQEAAGTASRLVCDAKSPHSSTGVKVLAFLSLAEVGQVAGPGPQRELKTVLLEALGSPSEDVRAAAAYALGRVGAGNLPDFLPFLLAQIEAQPRRQYLLLHALREALG--AAQPD---NLKPYVEDVWALLFQRCESPEEGTRCVVAECIGKLVFVNPPYLLPRFRKQLAAGQPYTRSTVITAVKFLISDQPHSIDPLLKSFIAEFMESLQDPDLNVRRATLTFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDMCEFLNHVEDGLKDHYDIRMLTFIMLARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQELEKQEELKRSAMRAVAALLTNPEVRKSPTVADFSAQIRSNPELTTLFESIQKDTASGPS-TDSMELS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75155-1", "uniprot_id": "CAND2_HUMAN", "id": "O75155-1", "name": "Cullin-associated NEDD8-dissociated protein 2", "aln": "-MSTAAFHISSLLEKMTSSDKDF--------------------------------------RFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQNLAVKCLGPLVVKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGVPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSPTAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLLRQTQPPKGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAAEALVVLQELVRALWPLHR---PRMLDPEPYVGEMSAVTLARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQLDLQPILAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYAKLISLLTAPVYE-------QAVDGGP----GLHKQVFHSLARCVAALSAACPQEAASTASRLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALG--AAQPD---SLKPYAEDIWALLFQRCEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHPIDPLLKSFIGEFMESLQDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMVARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKSPIMADFSSQIRSNPELAALFESIQKDSASAPS-TDSMELS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKY2-1", "uniprot_id": "CAND1_DROME", "id": "Q9VKY2-1", "name": "Cullin-associated NEDD8-dissociated protein 1", "aln": "MASHQYHQIANLLEKMTSTDKDF--------------------------------------RFMATNDLMTELQKDSIILDDESEKKVVRMVLKLLEDKNGEVQNLAVKCLGPLVNKVKEIQVETIVDSLCANMMSNTEQLRDISSIGLKTVIAELPQSSN--SLAPNVCQRITGKLSTAIEK-EDVSVKLESLDILADLLSRFGEFLVPFHSTILKALMPQLASSRQAVRKRTIVALSFLLIQANSNAYNGVIDHLLDGLENP---PNPAAIRTYIQCLASICRQAGHRLCNHIDRSMLLLSQYSQRDDDELREFCLQACEAFVMRCPDAINPHIPMILELCLNYITYDPNYNYETD-DGDTGNAMDTEDDEYVDSEEYSDDDDMSWKVRRAAAKCLEVLISTRQELVEDFYRSLSPALIARFKEREENVKSDIFHAYVALLKNTRLTDDVANDHDSMDQVSGPTSLLIEQLPLIVKAIQPLMREKSMKTRQDCFLLLRELLNSLPGALGPYLDSIVPGISYSLNDKSSTSNMKIESLGFLYSLLQGHPPHVFHPHIPLLVPLVVTSVFDPFYKIATEALLVLQQLVKVIRPLEPNAAKSDFDAPSFVGQVYSCTLQKLKVTDVDQEVKERAIACMGQIIANMGDMLQNELAVCLPIFMERLKNEVTRLSSVKALTLIAASSLRIDLTPILHDVLPALGTFLRKNHRALKLHSLDLINKIVINYSSNFEANLLQTAIVEIPPLISDSDLHVAQYSLTLLSTVARRQPQALVGIHEQFLRSVLILVRSPLLQGSALNCTLELFQALVQTQLSGLDYHSLVSKLMAPVLGGNGDVKSRATAGAPSEVVQLHKQAYHSSAKCIAALTQQCPQVATPLATKLITDLQKRNDT--EIIFCLLTIGEIGRHFDLSSIQVLPQTIIECFGATSEDVKAAASHALGAVSVGSLQTYLPLILHEIEVQPKRQYLLLHSLKEVISSLSVSPSGLAQLLPSVPSIWDQLFKHCECSEEGSRNVVAECLGKLVLVNPDELLPQLQQALRSESATMRTVVVSSVKFTISDQPQPIDVLLKQNIGEFLFALRDPEPQVRRVALVAFNSAVHNKPSLVRDLLPTLLPWLYSETKVKSELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLEQGLDRVDVMQFLDHVQAGLCDHYDIKMLTYLMTARLAILCPDKVLLRLDQFIQQLRDTCTHKVKANSVKQEYEKQDELKRSALRAVSALSQIPKANKNQQLVDFLKSIKETPELNKIFEYIQKDSITGSSDIIVMDQS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . *:.*******:**** *****.***:******* **::**:***: :*:****:.*************** **** ***.***:**:** *:.******:.******::*** ::. .** .**::***:*::** : ***:*:**:****:*:***:* * .**:::*:.*:***:*.* *****:: **..* ..:: : : ***:* * .* ..*:**** ****.*: ******* *:** : ::.::.: ******* **** ***: :**. :.**:* : .***:*:.:****::::* : : :: *:* .* ..:*******************: .***:* :*: **: :*:*.** *********:*:* **: **::*: ... : :. *.. :* *:**::**:* ::::.:::**.** *: ** . ***.*. :: :*.** :** * **:*.:::::*.** .** .*...****:* *:* *::.* *.***:*:***:***:**:.: **. :*. .:**:: : ** :*:.**:*********:*:*:::.::** * ::* * ::::**:**:***.::*****:* *.*::** *** :.* *.:*****:***:* :* :: :. . . .: . :::.:.*:*.*:.:.*:**** :: :*:**:: ** :** : .* .:* *::**** ...* .: ::**** *: . ::* .*:* * *** :. *.* ****.:** *:*:***: *** *: *::*: * :. :.: ::.:*::.*:*: . . : * .::*.:*:.****:***::*** *..*.* :**::* :**.:*:*******:*:*.:. :..*. .* * . .:* **::** .***:* *****:****:*** ***:::: * : . *:.*:::*** *****:.** ***. *.**: :*:**: :***.:*. **************** :** **.***:: :*******************:*********:***. *.::*: :**:**: ** *****:***::* **** *** ** *:*::*: ** *** ****.***** ***:******:***:** *:. *. :.** .*:..*** :** ****: :..* *: *", "identical_positions": 615, "similar_positions": 394, "identity": "47.49%" }, { "cls_id": "homologset.agr.RGD:620481", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88873-1", "uniprot_id": "GMEB2_RAT", "id": "O88873-1", "name": "Glucocorticoid modulatory element-binding protein 2", "aln": "MATP-DVSVHMEEVVVVTTPDTAVDGSGVEEVKTVLVTTNLAPHGGDLTEDNMETEN-AAAAACAFTASSQLKEAVLVKMAEEGENLEAEIVYPITCGDSRANLIWRKFVCPGINVKCVQYDEHVISPKEFVHLAGKSTLKDWKRAIRMNGIMLRKIMDSGELDFYQHDKVCSNTCRSTKIDLSGARVSLSSPTSTEYIPLTPAAADVNGSPATITIETCEDPGDWTTTIGDDTFAFWRGLKDAGLLDEVIQEFQQELEETMKGLQQRVQDPPLQLRDAVLLNNIVQNFGMLDLVKKVLASHKCQMDRSREQYARDLAALEQQCDEHRRRAKELKHKSQHLSNVLMTLTPVSLPSPMKRPRLARATSGPAAMASQVLTQSAQIALGPGMPMSQLTSVPLGKVVSTLPSTVLGKGSPQAAPASSPASPLLGGYTVLASSGSTFPSTVEIHPDTSSLTVLSTAAMQDGTTVLKVVSPLQLLTLP--GLGPTLQNVAQAS--PAGSTIVTMPTAAATGPEEHTATIEVAAVAEDHEQK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58929-1", "uniprot_id": "GMEB2_MOUSE", "id": "P58929-1", "name": "Glucocorticoid modulatory element-binding protein 2", "aln": "MATP-DVSVHMEEVVVVTTPDTAVDGSGVEEVKTVLVTTNLAPHGGDLTEDNMETENAAAAAAAAFTASSQLKEAVLVKMAEEGENLEAEIVYPITCGDSRANLIWRKFVCPGINVKCVQYDEHVISPKEFVHLAGKSTLKDWKRAIRMNGIMLRKIMDSGELDFYQHDKVCSNTCRSTKIDLSGARVSLSSPTSTEYIPLTPAAADVNGSPATITIETCEDPGDWTTTIGDDTFAFWRGLKDAGLLDEVIQEFQQELEETMKGLQQRVQDPPLQLRDAVLLNNIVQNFGMLDLVKKVLASHKCQMDRSREQYARDLAALEQQCDEHRRRAKELKHKSQHLSNVLMTLTPVPLPSPMKRPRLARATSGPAAMASQVLTQSAQIALSPGMPVSQLTSVPLGKVVSTLPSTVLGKGSPQAAPASSPASPLLGGYTVLASSGSTFPNAVEIHPDTSSLTVLSTAAMQDGSTVLKVVSPLQLLTLP--GLGPTLQNVAQAS--PAGSTIVTMPTATATGPEEHTATIEVAAVAEDHEQK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKD1-1", "uniprot_id": "GMEB2_HUMAN", "id": "Q9UKD1-1", "name": "Glucocorticoid modulatory element-binding protein 2", "aln": "MATP-DVSVHMEEVVVVTTPDTAVDGSGVEGVKTVLVTTNLAPHGGDLTEDNMETENAAAAAAAAFTASSQLKEAVLVKMAEEGENLEAEIVYPITCGDSRANLIWRKFVCPGINVKCVQYDEHVISPKEFVHLAGKSTLKDWKRAIRMNGIMLRKIMDSGELDFYQHDKVCSNTCRSTKIDLSGARVSLSSPTSAEYIPLTPAAADVNGSPATITIETCEDPGDWTAAIGDDTFTFWRGLKDAGLLDEVIQEFHQELVETMRGLQQRVQDPPLQLRDAVLLNNIVQNFGMLDLVKKVLASHKCQMDRSREQYARDLAALEQQCDEHRRRAKELKHKSQHLSNVLMTLTPVSLPPPVKRPRLARATSGPAAMASQVLTQSAQLALGPGVPVPQLTSVPLGKVVSTLPSTVLGKGSLQAPPASSPASPLLGGYTVLASSGSTYPSTVEIHPDASSLTVLSTAAVQDGSTVFKVVSPLQLLTLP--GLGPTLQNVAQAS--PGSSTIVTVPAGAAPGPEEHTATIEVAAMAEDHERK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QCL9-1", "uniprot_id": "E9QCL9_DANRE", "id": "E9QCL9-1", "name": "", "aln": "MASSSEVNVHMEEVVVVTTPDNISQASSPNEEKNILVATDLEDSEENIVEQSMESEAESSGAITLP------KDTVLVKISDD-TDVEGDILYPITCGDSKANLVWKKFVCPGINIKCVQLNEHLISPKEFVYIAGKSTLKDWKRAIRLNGTMLRKIMDSGELDFYQHSRLCSNTCRSTKIDLVGSRGSLSSQQSTETAPATPASTDVNGSSSSFSTD-VEDSTEWVTAIGEDTMTFWRGLKDAGMLEDVMEDLQKEIQEILKGLEERIQDPPLQVKDAALLNNIVQNFGMLDLVKKVLASHKSQMDRCREQYTRSLVALEQQCDEHRKRAKELKSKSQHLNNVLMTLTPVTSPPTTKRPRLTRAVSGPATVAS-TPAQPAHFTL----PITQLTGFPLEKVLS-----------------PQTQSPLISGYTLLTSPG-------EIQQDGSNLAMLSTAGP-GGPTIVKVVSPFQLVTLPTAGGGATVQNLAAPVGGAAGNTVVAVPVSAIN--TVNTATVETVGPQAENASDAKDDQE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:. :*.*************. :.*. : *.:**:*:* ::.*:.**:* ::.* *::****:::: ::*.:*:********:***:*:********:**** :**:*******::**************:** ****************.::************ *:* **** *:* * ***::*****.:::: : **. :*.::**:**::*********:*::*::::::*: * ::**::*:******::**.***********************.****.****:*.*.**********:****** *****.*********. *.. *****:**.****::** . :*.*:::* *:.***..** **:* ... ***:.***:*:*.* **: * *.*::****. .*.*:.*****:**:*** * *.*:**:* . ....*:*::*..: :***:*... :: . ", "identical_positions": 291, "similar_positions": 147, "identity": "53.79%" }, { "cls_id": "homologset.agr.RGD:620482", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13437-1", "uniprot_id": "THIM_RAT", "id": "P13437-1", "name": "3-ketoacyl-CoA thiolase, mitochondrial", "aln": "-MALLRGVFIVAAKRTPFGAYGGLLKDFTATDLTEFAARAALSAGKVPPETIDSVIVGNVMQSSS-DAAYLARHVGLRVGVPTETGALTLNRLCGSGFQSIVSGCQEICSKDAEVVLCGGTESMSQSPYSVRNVRFGTKFGLDLKLEDTLWAGLTDQHVKLPMGMTAENLAAKYNISREDCDRYALQSQQRWKAANEAGYFNEEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQNLPPVFKKEGTVTAGNASGMSDGAGVVIIASEDAVKKHNFTPLARVVGYFVSGCDPAIMGIGPVPAITGALKKAGLSLKDMDLIDVNEAFAPQFLAVQKSLDLDPSKTNVSGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGISLIIQNTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWT1-1", "uniprot_id": "THIM_MOUSE", "id": "Q8BWT1-1", "name": "3-ketoacyl-CoA thiolase, mitochondrial", "aln": "-MALLRGVFIVAAKRTPFGAYGGLLKDFSATDLTEFAARAALSAGKVPPETIDSVIVGNVMQSSS-DAAYLARHVGLRVGVPTETGALTLNRLCGSGFQSIVSGCQEICSKDAEVVLCGGTESMSQSPYCVRNVRFGTKFGLDLKLEDTLWAGLTDQHVKLPMGMTAENLAAKYNISREDCDRYALQSQQRWKAANEAGYFNEEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPSVFKKDGTVTAGNASGVSDGAGAVIIASEDAVKKHNFTPLARVVGYFVSGCDPTIMGIGPVPAINGALKKAGLSLKDMDLIDVNEAFAPQFLSVQKALDLDPSKTNVSGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIALIIQNTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42765-1", "uniprot_id": "THIM_HUMAN", "id": "P42765-1", "name": "3-ketoacyl-CoA thiolase, mitochondrial", "aln": "-MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSS-DAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL70-1", "uniprot_id": "Q9VL70_DROME", "id": "Q9VL70-1", "name": "", "aln": "MSAATKGIYIVAAKRTAFGTFGGSLKGINQTQLQTTAAKAALDAAGLKGEQVDTVIVGNVIASSSTDGIYVPRHVGLNCGVPIEKPALGINRLCGSGFQSIVNGAQDILVGGAKIALTGGVENMSQSPFIARNVRFGTTLGASYNLEDALWAGLTDTYCKLPMALTAENLADQYKISRERVDEFSLLSQKNWEKGQKEGAFNAEITPIKLKVKGKEVDFVVDEHPRPKTTIEGLNKLPSLFKKNGVVTAGTASGICDGASAVIVASEEALKEYNLKPLARLVAFSFVGVKPEIMGIGPVPAIQNVLKVSGKKLEDIDLIEINEAFAAQTLACADALKLDTSKLNVNGGAIALGHPLGASGSRITGHLVHELQRKKLKYGIGSACIGGGQGIALLLEAV-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :*:::******.**::** **.:. *:* **:***.*. : * :*:**:***: *** *. *:.*****. *:* *. ** :************.*.*:* *::.* **.*.***:*: .*******.:* . :***:**..*** : :***.:****** :::**** *.::* **:.*: .:. * ** *::**::*.* : : ****.**:**:* *::**.:***:*.****.***:.***..**:***:*:*::*:.****:*.: . * .* ********** ..** :* .*:*:**:::*****.* *: :*.** ** **.***********.******.******:*: **.:***********::::: . ", "identical_positions": 219, "similar_positions": 119, "identity": "54.89%" }, { "cls_id": "homologset.agr.RGD:620484", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZ86-1", "uniprot_id": "NOP58_RAT", "id": "Q9QZ86-1", "name": "Nucleolar protein 58", "aln": "-MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAFTALMEGKINKQLKKVLKK-IVKEAHEPLAVADAKLGGVIKEK-LNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASATLSEFLSEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVLAIRYDAFGED--SSSAMGAENRAKLEARLRILEDRGIRKISGTGKALAKAEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEEVDKEDEITEKKAKKAKIKIKAEVEEEM--EEAEEEQVVEEEPTVKKKKKKDKKKHIKEEPLSEEEPCTSTAVPSPEKKKKKKKKKDAED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6DFW4-1", "uniprot_id": "NOP58_MOUSE", "id": "Q6DFW4-1", "name": "Nucleolar protein 58", "aln": "-MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAFTALMEGKINKQLKKVLKK-IVKEAHEPLAVADAKLGGVIKEK-LNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASASLSEFLSEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQSSPKHKGKISRMLAAKTVLAIRYDAFGED--SSSAMGIENRAKLEARLRILEDRGIRKISGTGKALAKAEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEEVDKEDEITEKKAKKAKIKIKAEVEEEMEEEEAEEEQVVEEEPTVKKKKKKDKKKHIKEEPLSEEEPCTSTAVPSPEKKKKKKKKKDAED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2X3-1", "uniprot_id": "NOP58_HUMAN", "id": "Q9Y2X3-1", "name": "Nucleolar protein 58", "aln": "-MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAFTALMEGKINKQLKKVLKK-IVKEAHEPLAVADAKLGGVIKEK-LNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASAKLSELLPEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVLAIRYDAFGED--SSSAMGVENRAKLEARLRTLEDRGIRKISGTGKALAKTEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEQVDKEDEITEKKAKKAKIKVKVE-------EEEEEKVAEEEETSVKKKKKRGKKKHIKEEPLSEEEPCTSTAIASPEKKKKKKKKRENED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM69-1", "uniprot_id": "Q9VM69_DROME", "id": "Q9VM69-1", "name": "Nucleolar protein 58", "aln": "-MFVLYETPAGYAIFKLLDEKKLEQVDNLYQEFETPEKANKLLKLKHFEKFNDTTEALAAATAAVEGKVAKPLKKTLKKLLVDDVQSSLLVADAKLGTAIKDK-LSVQCVCNTGVQELMRCIRQQADSLLGGLPKREMTAMALGLAHSLSRYKLKFSPDKIDTMIVQAQCLLDDLDKELNNYMMRAREWYGWHFPELGKIITDNIAFVKTIKLVGTRDNMATSDLSDILPEDVEEKVKEAAEISMGTEISEEDVLNIQCLCDEIISINDYRTHLYDYLKARMMAMAPNLTVLVGDTVGARLIAHAGSLINLAKHPSSTVQILGAEKALFRALKTKKDTPKYGLIYHAQLVGQASQKNKGKMSRSLAAKASLATRVDAFGEE--ATFELGAAHKVKLESRLRLLEEGNLRKLSGTGKAKAKFEKYQAKSEVFTYQPEADNTLN-VKKKRKHSESEQQTPVKKE-------------------EPAEEEAEVKSE---KKKKKKKKQKDEEVEAVEEAAAPEPEDQPTPAKKKKKSKHQE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12499-1", "uniprot_id": "NOP58_YEAST", "id": "Q12499-1", "name": "Nucleolar protein 58", "aln": "MAYVLTETSAGYALLKASD-KKIYKSSSLIQDLDSSDKVLKEFKIAAFSKFNSAANALEEANSIIEGKVSSQLEKLLEE-IKKDKKSTLIVSETKLANAINKLGLNFNVVSDAVTLDIYRAIKEYLPELLPGMSDNDLSKMSLGLAHSIGRHKLKFSADKVDVMIIQAIALLDDLDKELNTYAMRCKEWYGWHFPELAKIVTDSVAYARIILTMGIRSKASETDLSEILPEEIEERVKTAAEVSMGTEITQTDLDNINALAEQIVEFAAYREQLSNYLSARMKAIAPNLTQLVGELVGARLIAHSGSLISLAKSPASTIQILGAEKALFRALKTKHDTPKYGLLYHASLVGQATGKNKGKIARVLAAKAAVSLRYDALAEDRDDSGDIGLESRAKVENRLSQLEGRDLRTTPKVVREAKKVEMTEAR----AYNADAD-----TAKAASDSESDSDDEEEEKK------------------EKKEKKRKRDDDEDSKDSKKAKKEKKDKKEKKEKKEKKEKKEKKEKKEKKSKKEKKEKK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** **..***::* : **: : ..* :::::.:*. * .*: *.**:.:::** .: :***: . *:* *:: : .: :..* *:::**. .*:. *... : .. . :: * *:. *: *: .::: *.******:.*::****.**:*.**:** .**********.* **.:**********.**::*.::: : : :* *.: : : **::*.*::* .** ***:*****::: *: ** *. :::.: ** :* :**. ** *:***:* :**: ********:***:.*** .:**:**************:::*******:***.****:: *:***::* ****: :: * **:.*: : :* :.*:* ** ** .:*. . . : * * : : :*:...* * . .: :.: :: * *:: ..: *..** *:*. : * .: :**.*.:::: ", "identical_positions": 196, "similar_positions": 181, "identity": "36.23%" }, { "cls_id": "homologset.agr.RGD:620485", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2TBE6-1", "uniprot_id": "P4K2A_MOUSE", "id": "Q2TBE6-1", "name": "Phosphatidylinositol 4-kinase type 2-alpha", "aln": "----MDETSP------------------------LVSPERAQPPEYTFPSGSGAHFPQVPGGAVRVAAAAG-------------------------SGPSPPC--SPG-----------------------HDRERQPLLDRARGAAAQGQTHTVAVQAQALAAQAAVAAHAVQTHRER---------------------------------------------------------------------------------NDFPEDPEFEVVVRQAEVAIECS-IYPERIYQGSSGSYFVKDS---QGRIVAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFN-----------YSAIDRVKSRGKRLALEKVPKVGQRFNRIGLP----------------PKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNR------------QLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCP------------------------------------------------------------------------MDNSSCR-----DTDWVMVREPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVP--FSQEIKDLILPKISDPNFIKDLEEDLYELFKRDPGFDRGQFHKQIAVMRGQILNLTQALKDNK--------------------------------------------SPLHLVQMPPVIVETARSHQRSASESYTQSFQ---------------SRKPFFSWW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99M64-1", "uniprot_id": "P4K2A_RAT", "id": "Q99M64-1", "name": "Phosphatidylinositol 4-kinase type 2-alpha", "aln": "----MDETSP------------------------LVSPERAQPPEYTFPSVSGAHFPQVPGGAVRVAAAG--------------------------SGPSPPC--SPG-----------------------HDRERQPLLDRARGAAAQGQTHTVAAQAQALAAQAAVAVHAVQTHRER---------------------------------------------------------------------------------NDFPEDPEFEVVVRQAEIAIECS-IYPERIYQGSSGSYFVKDS---QGRIIAVFKPKNEEPYGNLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFN-----------YSAIDRVKSRGKRLALEKVPKVGQRFNRIGLP----------------PKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNR------------QLLLQFERLVVLDYIIRNTDRGNDNWLIKYDYP------------------------------------------------------------------------MDNPNCR-----DTDWVMVREPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVP--FSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNK--------------------------------------------SPLHLVQMPPVIVETARSHQRSSSESYTQSFQ---------------SRKPFFSWW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BTU6-1", "uniprot_id": "P4K2A_HUMAN", "id": "Q9BTU6-1", "name": "Phosphatidylinositol 4-kinase type 2-alpha", "aln": "----MDETSP------------------------LVSPERAQPPDYTFPSGSGAHFPQVPGGAVRVAAAAG-------------------------SGPSPPG--SPG-----------------------HDRERQPLLDRARGAAAQGQTQTVAAQAQALAAQAAAAAHAAQAHRER---------------------------------------------------------------------------------NEFPEDPEFEAVVRQAELAIERC-IFPERIYQGSSGSYFVKDP---QGRIIAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFN-----------YSAIDRVKSRGKRLALEKVPKVGQRFNRIGLP----------------PKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNR------------QLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCP------------------------------------------------------------------------MDSSSSR-----DTDWVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVP--FSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNK--------------------------------------------SPLHLVQMPPVIVETARSHQRSSSESYTQSFQ---------------SRKPFFSWW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PE18-1", "uniprot_id": "P4K2A_DANRE", "id": "Q6PE18-1", "name": "Phosphatidylinositol 4-kinase type 2-alpha", "aln": "----MDETSP------------------------LVSPLRD-SNDFNY----GPAEPTSPRGGFGSTPGS--------------------------VVRLPAG--SPG-----------------------RSRERQPLLDRDRGASPR------------------------DPHR-----------------------------------------------------------------------------------NEFPEDPEFREIIRKAERAIEEG-IYPERIYQGSSGSYFVKDS---AGKIIGVFKPKNEEPYGQLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFN-----------YSAIDRVKSRGKRLALEKVPKVGQRFHRIGLP----------------PKVGSFQIFVEGYKDADFWLRRFEAEPLPENTNR------------QLQLQFERLVVLDYIIRNTDRGNDNWLIKYDYP------------------------------------------------------------------------MDTSSNR-----DSDWVLVKDPIIKLAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVV--FSQEIRDLVLPKLADPNFIKDLEEDLYELFKKDPGFDRGQFKKQVSVMRGQILNLSQAMRDGK--------------------------------------------TPLQLVQMPPVIVETARVPQRANSESYTQSFQ---------------SRRPFFTWW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VND3-1", "uniprot_id": "Q9VND3_DROME", "id": "Q9VND3-1", "name": "Phosphatidylinositol 4-kinase type 2", "aln": "MSGARDQTDPPLLQLEDEVDLIGDFAKDQPPPRNQLSPLLNGFESTSNQLTTKVEINTVGMGKRKTRRRGKKAREPMLLSVDDEDDEEEAQEERNHTNGLPPGEESAGGDAVIQKPQLDNLVMHYDDQIDDEDGEEAVLLKRSSNPRNQRLKGSAEDSIDSSSQQPPIICHIAPAKVASSALTSPLKTTSHTALARHPHDEADDICLVPEIDFEGMSTDAGSDNRESQPLLGGGNASHGSRISELLGGLGRGHDHVEFVSNTFGDDPLFSEIVAKAEGAIENG-VLPERIYQGSSGSYFVKDA---SHQCLAVFKPKDEEPYGRLNPKWTKWMHKLCCPCCFGRACLIPNQGYLSESGASLVDRKLNLNVVPKTRVVRLVAESFN-----------YARIDRQKAKLKKRIKEHYPSA--HFNRMSLP----------------LKTGSFQLFVEGYKDADYWLRRFESEPLPPSVAK------------SFQLQFERLVVLDYIIRNTDRGNDNWLIKYVAPKITTQVGGTGGRTMHGVVTPKLPNALGASKIVDLNEPPQASPKPTTGGRPSNHLAGGAATSAQQDSSSLASSEDEPSSRSPPTSEPDWNVVNSAFIRIAAIDNGLAFPFKHPDSWRAYPYHWAWLPQAKIP--FSEEIKEQVLPQLSDMNFVEEICTELLYLFQQDRGFDKRLFERQMSVMRGQILNLTQALRDGK--------------------------------------------SPVQLVQMPAVIVERS---SGSRFFSFTQRFQ---------------NKSPFFSWC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P42951-1", "uniprot_id": "LSB6_YEAST", "id": "P42951-1", "name": "Phosphatidylinositol 4-kinase LSB6", "aln": "MSNEAYQHDHTVN---------------PHQKIVVNSYDWLQFRDEQDHCKSKNPITHASPGVGSNAQNSDIAEAPQVFHPSYQSLVN-------VPSESPRPDQTSG------------------------SNPAVGLLHNAEDKASGQEEEGSQYEIQYSVFRPLHAYPTKGLAYEQLRRK-----------------------------------------------------------------------------EEQEQRENFNHLVSDCIEAVETFGRELERIQTGSSGSYFVYGTRADESVPVGVFKPKDEEPYGPFSPKWTKWAHRTFFPCLFGRSCLIPNLGYICESAASLLDRRLETHLVPYTDTASIESFNFYDNRKKWVLGYNLQKKKQKKLGSFQLFLKEYINADEFFHKYPLPGMYSDVKHSFHRKSSGEDINHKPETTRNLTDETEPSKQINSSPISTESEENSKFEWTESSLSQFRLELEKLIILDYIMRNTDRGLDNWMVKLIKLS-------------------------------------------------------------------------NNKWR----------------LKLAAIDNGLSFPWKHPDEWRLYPYGWLYLPLQLLAKPFSEQMRSHFLPILTSTNWWEESYQEFLALFSRDQDFNVRMWKKQWAVLKGQAFNVVETLKDPRQGPLELVRRTRCQVIDEKMQVPCCPPPVSIFKNAIDEPIGSYSTSPMVLPSTPSTIPFHAHNQSNSNPVYYDSTLHPFANKTVIAERLQIVNSTPVFTWC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * . * . * :.* . **.. . : : * :: .. *:* *** ******** .. :.*****:***** :.****** :: ** *** **: * **:.*:.***:*::*: ::** * .. : : .* .: * : :. .. *:: ** . . ... .* :::::.*:. . . .: *::*:*::****:****** ***::* . * :::*******:** ****.** **: * :** : **::::. .** ::. *: :: :: **.:* .*: :.:* :*::** :*: ::::* : :*: * . *..* : . : : . :: . *.*:* ", "identical_positions": 122, "similar_positions": 132, "identity": "14.9%" }, { "cls_id": "homologset.agr.RGD:620486", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62956-1", "uniprot_id": "ERBB4_RAT", "id": "Q62956-1", "name": "Receptor tyrosine-protein kinase erbB-4", "aln": "--------------------------------------------------------------MKLATGLWVWGSLLVAARTVQPSASQS-----------VCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVSTIGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDG-RCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHG--------DPYNAIDAIDPEKLNVFRTVREITGFLNIQTWPPNMTDFSVFSNLVTIGGRVLYS-GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTVNQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCP-----------------DVLQG----------------------------------ANSFIFKYADQD--------------RECHPCHPNCT---------------------------------------------QGCNGPTSHDCIYYP---------------------------WTGHSTLPQHARTPLIAAG------------------VIGGLFILVIMALTFAVYVRRKSIKKK----RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASVDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYIVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSK----FFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRSEIGHSPPPAYTPMSGSQFVYQDGGFATQQGMPMPYTATTSTIPEAPVAQGATAEMFDDSCCNGTLRKPVVPH-VQEDSSTQRYSADPTVFAPERNPRAELDEEGYMTPMHDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKA-EDEYVNEPLYLNTFTNALG-NAEYMKNSLLSVP---------------------------------------------------------------------------------------------------------------------------------EKAKKAFDNPDYWNHSLPPR-STLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61527-1", "uniprot_id": "ERBB4_MOUSE", "id": "Q61527-1", "name": "Receptor tyrosine-protein kinase erbB-4", "aln": "--------------------------------------------------------------MKLATGLWVWGSLLMAAGTVQPSASQS-----------VCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDG-RCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHG--------DPYNAIDAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYS-GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCP-----------------DGLQG----------------------------------ANSFIFKYADQD--------------RECHPCHPNCT---------------------------------------------QGCNGPTSHDCIYYP---------------------------WTGHSTLPQHARTPLIAAG------------------VIGGLFILVIMALTFAVYVRRKSIKKK----RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSK----FFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRSEIGHSPPPAYTPMSGNQFVYQDGGFATQQGMPMPYRATTSTIPEAPVAQGATAEMFDDSCCNGTLRKPVAPH-VQEDSSTQRYSADPTVFAPERNPRGELDEEGYMTPMHDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKA-EDEYVNEPLYLNTFANALG-SAEYMKNSVLSVP---------------------------------------------------------------------------------------------------------------------------------EKAKKAFDNPDYWNHSLPPR-STLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15303-1", "uniprot_id": "ERBB4_HUMAN", "id": "Q15303-1", "name": "Receptor tyrosine-protein kinase erbB-4", "aln": "--------------------------------------------------------------MKPATGLWVWVSLLVAAGTVQPSDSQS-----------VCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDG-RCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHG--------DPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYS-GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCP-----------------DGLQG----------------------------------ANSFIFKYADPD--------------RECHPCHPNCT---------------------------------------------QGCNGPTSHDCIYYP---------------------------WTGHSTLPQHARTPLIAAG------------------VIGGLFILVIVGLTFAVYVRRKSIKKK----RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSK----FFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPH-VQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKA-EDEYVNEPLYLNTFANTLG-KAEYLKNNILSMP---------------------------------------------------------------------------------------------------------------------------------EKAKKAFDNPDYWNHSLPPR-STLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UZ77-1", "uniprot_id": "A0A8N7UZ77_DANRE", "id": "A0A8N7UZ77-1", "name": "Receptor protein-tyrosine kinase", "aln": "--------------------------------------------------------MDMQPLHTNKMRSDILIALFLTAVIVPLCTSQS-----------VCPGTDNKLSTLSDLDQQYKTLRKFYENCEVVMGNLEITSIER-NRNLSFLKSIREVTGYVLVALNQFDYLPLENLRIIRGTKLYEGRYSLAIFLNYRRDGYFGLRQLGLKNLTEILNGGVYVDQNKFLCHADTIHWHDIIKNPRSELLVVPSNNSGNTCRRCHRSCNGRCWGHQEDQCQSLTKTVCAEQCDG-RCFGPYVSNCCHRECAGGCFGPKDTDCFACTNFNDSGACVTQCPQPFVYNPTTFQLEHNPNAKYTYGAFCVKKCPHNFVVDHSSCVRACPSNKMEVEENQTKMCIPCTDICPKVCDGIGTGSLQMAQTVDSSNIEKFVNCTKINGNLIFLITGIKG--------DMFHGIRALDPDRLNVFRTVREITGFLNVQSWPENMTDLGVFSNLATIGGRSLYS-GISLLILKQRWITSLQFQSLREISAGNVYMTNNSQLCFYSTVNWTSLFRTSTQRALIKNNREPRECSKEQKICDPLCSEAGCWGPGPDQCLSCKYFSRGKTCVKSCNLYYGDVREFANGSVCVECDSQCEKAGEKGLTCHGPGPDHCVKCLHLKDGPNCVEKCP-----------------DGLQG----------------------------------ANSFIFKYAETN--------------NECHPCHPNCT---------------------------------------------QGCTGPRIQDCVG-------------------------------------ILDRTPLIAAG------------------LIGGLFVIVIIALGVAVYIRRKSIKKK----RALRRFLETELVEPLTPSGAAPNQAQLRILKETELKRVKILGAGAFGMVYKGIWVPEGETVKIPVAIKILNESTGPKANVEFMDEALIMASMEHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHQDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHIKITDFGLARLLDTDEKEYNSDGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTRDIPDILEKGERLPQPPICTIDVYMVMVKCWMIDADSRPRFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNHST----FFKSLLDEEELDDLMDADEYLVPQTCNISTSTYTSRTTMDASWT-LRCRD---------RVFSPEDGMGACSRDVPASASAVFVPV----STQAAGLNVLEEQHCNGSLKKQQPMSGSGDDCDGQRYSADPTVFLGERSLKN-TDEDGYMSPMN-KSTSDHLSPVEENPFVNHRKNGNITALDNPGYHSTPDKKSKAEEDEYINEPLYLNAYNTTGGTNLEIMRRNGSSIPLQMTTATSAASSHIILSTQPGKAHHHGQGTHVHFAIPPVQPPQTRAMSQNGQHSQSSHAVESNSSSMSANPSLLSQISLVSQQIQPCLASQSQVPKSTVPNKSISGLPGHLVYPVNMLQTGHTGTVMADRKSKKNFDNPDYWQHSLPPKVTQANPQDPTQTCKSKHLYRHSIRSRLAVADNPEFVSEFNKRPGPVLPPPPYRHRNTVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q7Y5-1", "uniprot_id": "A0A8M9Q7Y5_DANRE", "id": "A0A8M9Q7Y5-1", "name": "Receptor protein-tyrosine kinase", "aln": "---------------------------------------------------------------MWPVRFLLLFCLVFTFAVLQRSSGQS-----------VCPGTDNKLSTLSDLDQQYKTLRKFYENCEVVMGNLEITSIER-NRNLSFLKSIREVTGYVLVALNQFDYLPLENLRIIRGTKLYEGRYSLAIFLNYRRDGYFGLRQLGLRNLTEILNGGVYVDQNKFLCHADTIHWQDIIKNPRSELLVVPSNNSGNTCRRCHRSCNGRCWGPQEDQCQSLTKTVCAEQCDG-RCFGPYVSNCCHRECAGGCFGPKDTDCFACTNFNDSGACVTQCPQPFVYNPTTFQLEHNPNAKYTYGAFCVKKCPHNFVVDHSSCVRACPSNKTEVEENNIKMCIQCTEICPKMCDGIGTGSLQSAQTVDSSNIEKFVNCTKINGNLIFLITGIKG--------DMYHGIRALDPERLNVFRTVREITGYLNIQSWPENMTDLSVFSNLVTIGGRTLYS-GISLLILKQRWITSLQFQSLREISAGNVYMTNNSQLCFYSTVNWTSLFRTSTQKAKIKDNRDPRECSQQRMVCDPLCSVSGCWGPGPNQCLSCKYFSRGRTCVRSCNLYNGDVREFANGSTCVECDSQCEKAEDKSLTCHGPGPDHCVKCLHLKDGPNCVEKCP-----------------DGLQG----------------------------------ANSFIFKYPETN--------------NECHPCHPNCT---------------------------------------------QGCTGPRIQDCIG-------------------------------------ILDRTPLIAAG------------------VIGGMFVVVIVALGFAIFFRRKSIKKK----RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKILGTGAFGTVYKGIWVPEGETVKIPVAIKILNESTGPKANVEFMDEALIMASMEHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHQDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHIKITDFGLARLLETNEKEYSADEGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDILEKGERLPQPPICTIDVYMVMVKCWMIDADSRPRFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNHSK----FFQSLLDEEELDDLMDADEYLVPHSLNAPPTSHIPHPHVDSNQNQFGYHD---------GSRCPEDVT--RFHEVAAAGNAPSALG----SAQRAGLDLVEEQHCNGSLKKQATVH-SVEDSSGQRYSADPTVLLGEKTQREDTDEDGYMSPMKDKISTNHLNPVEENPFVTRRKSKDVHALDNPGYHNTPDGKPKC-EDEYINEPLYLNTFNNTSDIHQEMLRKNGVSIPAQMTTAG-----HILQT---GKPHHHSHGPHVHFAIPPVQPVHPGPMSQNDHN---AHSVQSGHDHAVKSGPSAGQICLVSHQVQQGHPSKSNRSPQQFQLSGGK-LPGHPVQPG-----SQIGTVLVDKMYKNSFDNPEYWQHSLPP--PQISQDSSSAVCNNKFLYKQNGRVQPPAAENPEYLSGVK--PGMVLPPPPYRQRNTVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P04412-1", "uniprot_id": "EGFR_DROME", "id": "P04412-1", "name": "Epidermal growth factor receptor", "aln": "MLLRRRNGPCPFPLLLLLLAHCICIWPASAARDRYARQNNRQRHQDIDRDRDRDRFLYRSSSAQNRQRGGANFALGLGANGVTIPTSLEDKNKNEFVKGKICIGTKSRLSVPSNKEHHYRNLRDRYTNCTYVDGNLKLTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIRGRTLFSLSVEEEKYALFVT--YSKMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVSNGTDAYYNYDFTAPERECPKCHESCTHGCWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPRECCHLFCAGGCTGPTQKDCIACKNFFDEAVSKEECPPMRKYNPTTYVLETNPEGKYAYGATCVKECPGHLLRDNGACVRSCPQDKMDKGGE----CVPCNGPCPKTCPGV--------TVLHAGNIDSFRNCTVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERREVFSTVKEITGYLNIEGTHPQFRNLSYFRNLETIHGRQLMESMFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVSNIRWPAIQKEPEQKVWVNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGTCIADCGYIS-NAYKFDN-RTCKICHPECR-------TCNGAGADHCQECVHVRDGQHCVSECPKNKYNDRGVCRECHATCDGCTGPKDTIGIGACTTCNLAIINNDATVKRCLLKDDKCPDGYFWEYVHPQEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQRECFQRHPECNGCTGPGADDCKSCRNFKLFDANETGPYVNSTMFNCTSKCPLEMRHVNYQYTAIGPYCAASPPRSSKITANLDVNMIFIITGAVLVPTICILCVVTYICRQKQKAKKETVKMTMALSGCEDSEPLRPSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCMSSQMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRVFTSKSDVWAFGVTIWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHLDAAMRPTFKQLTTVFAEFARDPGRYLAIPGDKFTRLPAYTSQDEKDLIRKLAPTTDGSEAIAKPDDYLQPKAAPGPSHRTDCTDEMP---------------KLN--------------------------------------------RYCKDPSNKNSSTG------DDERDSSAREVGVGNLRLDLPVDEDDYLMPTCQPGPNNNNN-------MNNPNQNNMAAVGVAAGYMDLIGVPVS-----VDNPEYLLN-AQTLGVGESPIPTQTIGIP--------------------------------------------------------------------------------------------------------------------------------------VMGGPGTMEVKVPMP-------GSEPTSSDHEYYNDTQRELQPLHRNRNTETRV--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . : . . :* **..:** *: :::*: **. * ** * ***::* : . * :**** .:******:*:: :. : : :*:**** .*:. : : : * : :* ::*** * ..:* **: **:* :*: * . * :**.**. *** .:**.::: .*: ** * **:** :*** ***** **.:.**:** ** *.... :** *****: ** * :.**:*** ***:** ::: * .:***:**..* : : * *. *** * *: .:.:.**:.* *** *:**: :* : * .:**:: :** **:****:**:: :: ::. * ** ** ** * . :: * : : : **:::.*::**:*.: : .* :**: .:.*.:: *: :.:* . * : :*. *. ****.*.:***:*: *. . *: .*. : :* * * *..:*. **:*.*.*:* :* *.:** :**.:** * * .:.::::* . : .:*** ** :**.** .** * **. : *.::: .* * .. :. *:. * * : : * *** **. ..* .:***:*::**:: :** **** ****:******.******** * ::**.::. **: ** **** :* :*::**.**:*. : *:***** ****:**::::*:***: ****..****** ****:**************::*. :********:**. :.:**.: *******:*****: * ** :****::*******:*** :*::.**:::***::* * :* ** **::*:* .::.** :** ** **:*:: *:.:**** ***.* **. :**: . . : : : : : ..::** *:: .. : *:.. .* . :* *: * : **:.*: * : . :.. :. :: *:. . : . . :::* ** : . . : . .:* :..* : .:* . . : *... * * : : . ", "identical_positions": 420, "similar_positions": 353, "identity": "24.88%" }, { "cls_id": "homologset.agr.RGD:620488", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TB92-1", "uniprot_id": "MILR1_MOUSE", "id": "Q3TB92-1", "name": "Allergin-1", "aln": "MGDGDSPMCLSAVSFKGIRCWLDKLLLWALTISITLQNAAVDCTRVENNELPSPNLNSSMNVVRMGQNVSLSCSTKNTSVDITYSLFWGTKYLESKRRRGGAVDFHLRISNANESGPYKCKVNVSNLMKYSQDFNFTMAK-----------------------------------------------------------------------------------------------DESCPSCRLSLLLPGLLLGILVIVLVLAYLIHLKYKKG--KKTQREDQSKGSGDAPAQDELYVNACKTQ---------------------TEQPQEIHYATPVFKEMAPMEEEGGTDGKADYIYSELTH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62875-1", "uniprot_id": "MILR1_RAT", "id": "Q62875-1", "name": "Allergin-1", "aln": "MGDDDTPVCLSVASCKGVSCWLDKLLLWALTLSITLRNTAVDCRRVDRNGLLSPNLNSSMSVVRMGQNVSLSCSSKNTSIDITYSLFLGKRYLESKRRRGGAVDFHLRISNANESGPYKCKVNDSNSSKYSQNFNFTIIQ-----------------------------------------------------------------------------------------------DESCSSCLLSLLLPGVLLG--LILPGLAFLIYLKYKKGCTGKTLKENESKGSGDAPTQGELYANICETQK-------------------GSEQLQEIHYTTPVFKEVAPTEQEGLEDRKDDYIYSELTY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z6M3-1", "uniprot_id": "MILR1_HUMAN", "id": "Q7Z6M3-1", "name": "Allergin-1", "aln": "-----------------MWSHLNRLLFWSIFSSVTCRKAVLDCEAMKTNEFPSPCLDSKTKVVMKGQNVSMFCSHKNKSLQITYSLFRRKTHLGTQDGKGEPAIFNLSITEAHESGPYKCKAQVTSCSKYSRDFSFTIVDPVTSPVLNIMVIQTETDRHITLHCLSVNGSLPINYTFFENHVAISPAISKYDREPAEFNLTKKNPGEEEEYRCEAKNRLPNYATYSHPVTMPSTGGDSCPFC-LKLLLPGLLLLLVVIILILAFWVLPKYKTR---KAMRNNVPRDRGDTAMEVGIYANILEKQAKEESVPEVGSRPCVSTAQDEAKHSQELQYATPVFQEVAPREQEACDSYKSGYVYSELNF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *::**:*:: *:* :::.:** :. * : ** *:*. .** *****: ** **.*::****** . :* :: :* .. *:* *::*:********.: :. ***::*.**: . .:**. * *.*****:** :*: **: : ***. *: ::: .:. **:. : :*.* :.* ::: **::*:****:*:** *:*. . * .*:****..", "identical_positions": 92, "similar_positions": 82, "identity": "25.27%" }, { "cls_id": "homologset.agr.RGD:620489", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIX0-1", "uniprot_id": "DJC14_RAT", "id": "Q5XIX0-1", "name": "DnaJ homolog subfamily C member 14", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MAQKHPGERGLCGVHHSGGSSLITSGSSVDPEILSFSGLRDSKETAPNGTRCLKEHSDPKCTQPPNP--------------------------------------AHWSDPSHGPPRGPGPPREGGYPDESETCSEE-SGVDQELSRENETGYQEDGSPSFLPIPSACNCQGSPGVPEGT--------------CSEEGDGSSSSFCHHCTSPALGEDEELEEEYDDEEPLKFPSDFSRVSSGKKPPSRRQRHRFLTKEDVRDSGRRDPKAPGRHRLARKRSQTDKRRGLGLWGVEELCQLGQAGFWWLIELLVLVGEYVETCGYLIYACRK----LKGSDLDLFRIWVGVWARRLGGWARVMFQFLSQSFFSVAGLFIRLLR---VVGAFLLLALALFLGCLQLGWRFLVGLGDRLGWRGKAAWLFSWLDSPALHHFLTLLKD------------------------------------SRPWQQLVRVIQWGWLELPWVKQRTQRQGTAHVASGR-----------------------YCQPEEEVARLLTMAGVPED------------ELNPFHVLGVEATASDIELKKAYRQLAVMVHPDKNHHPRAEEAFKVLRAAWDIVSNPERRKEYEM---KRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNR----------------LHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFG------SRVPGTSGRQRATPES----PPADLQDFLSRIFQVPPGPMS---NGNFFAAPHPGPGTTSTSRPNSSVPKGEAKPKRRKKVRRPFQR------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921R4-1", "uniprot_id": "DJC14_MOUSE", "id": "Q921R4-1", "name": "DnaJ homolog subfamily C member 14", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MAQKHPGERRLCGAHRSGGTSLSTSGSSVDPEILSFSGLRDSAETAPNGTRCLKEHSGPKYTQPPNP--------------------------------------AHWSDPSHGPPRGPGPPRGGGYPDESETGSEE-SGVDQELSRENETGYQEDGSPSFLSIPSACNCQGSPGVPEGT--------------YSEEGDGSSSSLCHHCTSPALGEDEELEEEYDDEEPLKFPSDFSRVSSGKKPLSRRQKHRFLIKEDVRDSGRREPKAPGRHRLARKRSQTDKRRGLGLWGVEELCQLGQAGFWWLIELLVLVGEYVETCGHLIYACRK----LKGSDLDLFRVWVGVWARRLGGWARMMFQFLSQSFFCVVGLLIRILR---VVGAFLLLALALFLGCLQLGWRFSVGLGNRLGWRDKTAWLFSWLGSPALHHCLTLLKD------------------------------------SRPWQQLVRLIQWGWQELPWVKQRTKKQGNAPVASGR-----------------------YCQPEEEVTRLLTMAGVPED------------ELNPFHVLGVEATASDTELKKAYRQLAVMVHPDKNHHPRAEEAFKILRAAWDIVSNPERRKEYEM---KRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNR----------------LHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFG------SRVPGTSGRQRATPES----PPADLQDFLSRIFQVPPGPMS---NGNFFAAPHPGPGTTSTSRPNSSVPKGEAKPKRRKKVRRPFQR------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6Y2X3-1", "uniprot_id": "DJC14_HUMAN", "id": "Q6Y2X3-1", "name": "DnaJ homolog subfamily C member 14", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MAQKHPGERGLYGAHHSGGASLRTLGPSVDPEIPSFSGLRDSAGTAPNGTRCLTEHSGPKHTQHPNP--------------------------------------AHWLDPSHGPPGGPGPPRDAEDPDQSETSSEEESGVDQELSKENETGNQKDGN-SFLSIPSACNCQGTPGIPEGP--------------YSEGGNGSSSNFCHHCTSPALGEDE-LEEEYDDEESLKFPSDFSRVSSGKKPPSRRQRHRFPTKEDTREGGRRDPRSPGRHRLGRKRSQADKRKGLGLWGAEELCQLGQAGFWWLIELLVLVGEYVETCGHLIYACRQ----LKSSDLDLFRVWMGVWTGRLGGWAQVMFQFLSQGFYCGVGLFTRFLK---LLGALLLLALALFLGFLQLGWRFLVGLGDRLGWRDKATWLFSWLDSPALQRCLTLLRD------------------------------------SRPWQRLVRIVQWGWLELPWVKQNINRQGNAPVASGR-----------------------YCQPEEEVARLLTMAGVPED------------ELNPFHVLGVEATASDVELKKAYRQLAVMVHPDKNHHPRAEEAFKVLRAAWDIVSNAEKRKEYEM---KRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNR----------------LHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFG------SRIPGTRGRQRATPDA----PPADLQDFLSRIFQVPPGQMP---NGNFFAAPQPAPGAAAASKPNSTVPKGEAKPKRRKKVRRPFQR------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TX49-1", "uniprot_id": "A0AB32TX49_DANRE", "id": "A0AB32TX49-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MFRYLSKMEADMAVHWDTVEENTDRETPSVSLASSYLENDTHHGPFECEHEAMDDFDCEFP--------------------------------------DEDFDLDENEEQNAKTEDLIDNQAEDEEKSDE-------LRDEGETKSRNAGS-------------GRKGKSKK--------------------SGLGTGFYDQTQS------------------------WTSSSSSSMP-----HKSFLASSRHKQVRRRNHHLHNHSRVRRKNGIP-----LVMVCRDFLSDFVSP---WCISCIHMFVELIISLTHRCGLLVE----SSGIALYDFGTQMLSKVTDIPGLTQDMRRIVDWSRCWTVALIDGIVRSTCKARNSLLSTLGFVRVALSAGSQMMKCVVGRLAGERGRKWWLAFQSSRIWRKVSDLCVR------------------------------------IRGWR------------FKRGAGSENSNPESPNRGAE-----------------------KWQPGEELQRLLALAKIPEE------------ELDPFNVLGVDVHATESELKRAYRQLAVQVHPDKNKHPGAGEAFKVLRAAWDIVSNPETRREYEL---KRMAATELSKSMNEFLTKLQDDLKEAMNTMMCTKCEGALRWTESPARLDSVLNVINGTVPRRETCGPSPACWDCALHSSHSWTEKSLTSLSGQAVSGSASLQTHTECRITSPSALKVAVGPAATDHPQITQQAGVLQQTCRISSTASSRLALPVTRLQTEDSSLQETLLITAPDPPLELLPCFQDLLLSRAFSAPGLSVAMLANTGLKEQNLHAAARKCANRSSAEMRRKTHRCSGVCVFAHERTTPGDRLLIQCWCFSSFLMMKPQHGDSQRSEQRSAG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN28-1", "uniprot_id": "Q9VN28_DROME", "id": "Q9VN28-1", "name": "J domain-containing protein", "aln": "MATRQDDEIGGGSTESAPFRVLPHTDEVGNYLAHQQQQQQQQQHQHQTQNYLIHQQQHGQAPVPLMWPPPPPHLAGPPFAPHLQQQQPHMYNEYLFNLSYSGQPGQPETYSVLPVGPGNFLKVYHCPDNQVSEAGTPLFTHINMASINHHQLQHQHQAAPPTPSQPTPLYELFATNPLTLPHAQQQDAQHRQPQQTQTQAPTVSQVNHSSSSANLLINNLVNNWSPNLTGGSYIQFDGEANEMDVVLETSIAQQPQVPNQNLQQPEPLSQS-VNTLPAASKPAKSLKMPLATATVSPTAINKSSVAVPGQPEGKKRIVAEVKPMPMSYSDVLSKGTKPSAAGRDMRADNGGDYSVQSQRRPEKEDAYGNREMRTSKRSPLHDAKETGSFVPGVGHAHASRGKKRSKVSQTAPLKVQQSQSLAQPNLQPQIKSNKLNNPEKKRPLQPKNVNSNAPKFSEHKTTPVSANSSLQNHSNVLNFTPATNSSTSSRKSGSNKINSNASHSNHTGANTHAGSSSSSSSVNYSSNNNVSSSSAKRYSSSNLNPNNSSGYSYSSKRNRSNAYSSTNSPTHANSFSSNRNYELAKRIIHTWWIYTLKLLTWLFYLVYDIVVLGFSMGYERITLAYVAALAYARQLQKELKQNSGKPSIWWRSYWRRFDARFAKNSRLAVWRLFYKRKPPETTSEQFKTGRLPQTGEEAMYSLLNCKGKDAYSILGVPPDSSQEQIRKHYKKIAVLVHPDKNKQAGAEEAFKVLQRAFELIGEPENRLIYDQSIAETLHTEKAWTELHDLLSQLQTKMAEAANTIRCSTCAQRHPRKLTERPHYAARECASCKIR----------------HSAKDGDIWAETSMMGLRWKYLALMDGKVYDITEWANCQKGALS-HLEPNSHMVQYR-------IVRGAQQQQQQQQQQ-----QQQQQQQHHQHPQQPHHDRGVHHPGGGVSGVSEATLHEFLDNLYSGQHPGAHNAFAGNARRRTRRN------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . . . . .: :* . : * . * . : * *:. :: .. . * .: .* .. : *. . * . * . : * . : .: .. :. : : : . : * . . :. : . . . :. . .: . . :: .: : : :. : : . :* * . : . :*: :.: :*** ::: :::: *:::** ******::. * ****:*: *::::.:.* * *: : : : .::::*::** .: ** **: *: * :. . . *.:.. : :*: * . * :: :. ... : .:. . . : .: : . *: * . .: .. : :. : .*. . ", "identical_positions": 53, "similar_positions": 163, "identity": "5.03%" }, { "cls_id": "homologset.agr.RGD:62049", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17077-1", "uniprot_id": "RL9_RAT", "id": "P17077-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQPDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32969-1", "uniprot_id": "RL9_HUMAN", "id": "P32969-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P51410-1", "uniprot_id": "RL9_MOUSE", "id": "P51410-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKTILSNQTVDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A140T8T4-1", "uniprot_id": "A0A140T8T4_MOUSE", "id": "A0A140T8T4-1", "name": "Large ribosomal subunit protein uL6", "aln": "MKTILSNQTVDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFQYKMRSVYAHFPINVVIQENG--SLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50882-1", "uniprot_id": "RL9_DROME", "id": "P50882-1", "name": "Large ribosomal subunit protein uL6", "aln": "MRTINSNQCVKIPKDIKASVKARVVTITGTRGTLKRSFKHLALDMYMP--DKRTLKVEKWFGTKKELAAVRTVCSHIENMIKGVTFGFQYKMRAVYAHFPINCVTSENN--TVIEIRNFLGEKYIRRVEMAPGVTVVNSTAQKDELIVEGNDIESVSGSAALIQQSTTVKNKDIRKFLDGLYVSEKTTVVKLES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05738-1", "uniprot_id": "RL9A_YEAST", "id": "P05738-1", "name": "Large ribosomal subunit protein uL6A", "aln": "MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVN--NQLIKVAVHNGGRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFITEDL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P51401-1", "uniprot_id": "RL9B_YEAST", "id": "P51401-1", "name": "Large ribosomal subunit protein uL6B", "aln": "MKYIQTEQQIEIPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVN--NQLIKVAVHNGDRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFIVEDM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * ::* :.:*:.: ::*.* * : *.**** :.::*: : : :: ::* * :*.:*::**: * ::***.*** *::**** ******** *:. ..:*:*****:* **.* : **: * ***:::.**.:* ** .** :** *:**********:***.* : : ", "identical_positions": 80, "similar_positions": 59, "identity": "41.24%" }, { "cls_id": "homologset.agr.RGD:620490", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q10468-1", "uniprot_id": "B4GN1_RAT", "id": "Q10468-1", "name": "Beta-1,4 N-acetylgalactosaminyltransferase 1", "aln": "MRLDRRALYALVLLLACASLGLLYASTRDAPGLPNPLALWSPPQGPPRLDLLDLAT---EPRYAHIPVRIKEQVVGLLAQNNCSCESSGGRFALPFLR----QVRAIDFTKAFDAEELRAVSISREQEYQAFLARSRSLADQLLIAPANSPLQYPLQGVEVQPLRSILVPGLSLQEASVQEIYQVNLIASLGTWDVAGEVTGVTLTGEGQSDLTLASPILDKLNRQLQLVTYSSRSYQANTADTVRFSTKGHEVAFTILIRHPPNPRLYPPSSLPQGAQYNISALVTVATKTFLRYDRLRALIASIRRFYPTVTIVIADDSDKPERISDPHVEHYFMPFGKGWFAGRNLAVSQVTTKYVLWVDDDFVFTARTRLEKLVDVLERTPLDLVGGAVREISGYATTYRQLLSVEPGAPGFGNCLRQKQGFHHELAGFPNCVVTDGVVNFFLARTDKVRQVGFDPRLNRVAHLEFFLDGLGSLRVGSCSDVVVDHASKVKLPWTSKDPGAELYARYRYPGSLDQSQVAKHRLLFFKHRLQCMTAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q09200-1", "uniprot_id": "B4GN1_MOUSE", "id": "Q09200-1", "name": "Beta-1,4 N-acetylgalactosaminyltransferase 1", "aln": "MRLDRRALYALVLLLACASLGLLYSSTRNAPSLPNPLALWSPPQGPPRLDLLDLAP---EPRYAHIPVRIKEQVVGLLAQNNCSCESKGGSLPLPFLR----QVRAVDLTKAFDAEELRAVSVAREQEYQAFLARSRSLADQLLIAPANSPLQYPLQGVEVQPLRSILVPGLSLQEASVQEIYQVNLSASLGTWDVAGEVTGVTLTGEGQPDLTLASPVLDKLNRQLQLVTYSSRSYQANTADTVRFSTKGHEVAFTILVRHPPNPRLYPPSSLPQGAEYNISALVTIATKTFLRYDRLRTLIASIRRFYPTVTIVIADDSDKPERISDPHVEHYFMPFGKGWFAGRNLAVSQVTTKYVLWVDDDFVFTARTRLEKLVDVLEKTPLDLVGGAVREISGYATTYRQLLSVEPGAPGLGNCFRQKQGFHHELVGFPSCVVTDGVVNFFLARTDKVRQVGFDPRLNRVAHLEFFLDGLGFLRVGSCSDVVVDHASKVKLPWTAKDPGAETYARYRYPGSLDQSQVAKHRLLFFKHRLQCMTAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00973-1", "uniprot_id": "B4GN1_HUMAN", "id": "Q00973-1", "name": "Beta-1,4 N-acetylgalactosaminyltransferase 1", "aln": "MWLGRRALCALVLLLACASLGLLYASTRDAPGLRLPLAPWAPPQSPRRPELPDLAP---EPRYAHIPVRIKEQVVGLLAWNNCSCESSGGGLPLPFQK----QVRAIDLTKAFDPAELRAASATREQEFQAFLSRSQSPADQLLIAPANSPLQYPLQGVEVQPLRSILVPGLSLQAASGQEVYQVNLTASLGTWDVAGEVTGVTLTGEGQADLTLVSPGLDQLNRQLQLVTYSSRSYQTNTADTVRFSTEGHEAAFTIRIRHPPNPRLYPPGSLPQGAQYNISALVTIATKTFLRYDRLRALITSIRRFYPTVTVVIADDSDKPERVSGPYVEHYLMPFGKGWFAGRNLAVSQVTTKYVLWVDDDFVFTARTRLERLVDVLERTPLDLVGGAVREISGFATTYRQLLSVEPGAPGLGNCLRQRRGFHHELVGFPGCVVTDGVVNFFLARTDKVREVGFDPRLSRVAHLEFFLDGLGSLRVGSCSDVVVDHASKLKLPWTSRDAGAETYARYRYPGSLDESQMAKHRLLFFKHRLQCMTSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDH6-1", "uniprot_id": "A0A8M2BDH6_DANRE", "id": "A0A8M2BDH6-1", "name": "Beta-1,4 N-acetylgalactosaminyltransferase", "aln": "----MRSLRKTVLLALVASVVLVLAVLHSWPTRVYSTVDVRYRPGPGAERLLEERLPELDPSASTIPYRVRESVARLLARNGCVCEGESRGVNLPFAQLLFPRVSAHPLHTAFQASQLDEMKKRRAKEYQSFQMRSQTPADLLIVAEANNPLQYPTQGVEVRPLKTILIPGLALKELP-RDVYTLNFSASLGTFNVAAEVEGVKVRGDGEMHMTLSSSVLSSLNRQLQFITYTNTLFHPSTADTVQLDTEGHQALFTIKIRHGVTPKLYNTGSDAD-KEYNISALVTIATKTFLRYDKLQNLIDSIRQYYPTVTIVIADDSEHPKTVSGPYIEHYIMPFGKGWFAGRNLAVSQVTTKYVLWVDDDFIFSANTKLEKLVDVLEKTTLDLVGGAVREATGYTATYRQTISIEAGEE-DGDCLHMRRGFHHIIQGFPHCVITDGVINFFLARTDKVQQVGFDPRLARVAHLEFFIDGLGSLHVGSCDDVIVNHATKIKLPWGQSES-DKTYAKFRYPPASSDATHTKNGLLYFKNRFQCLTHN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* *** **: *: : :. * . . .* * : :* : ** *::*.*. *** *.* **... . *** : :* * : .**:. :* . * :*:*:* **:: ** *::* **.***** *****:**::**:***:*: . :::* :*: *****::**.** **.: *:*: .:** *. *..******::**:. ::..*****::.*:**:. *** :** .*:** ..* .: :********:*********:*: ** ***::*****:******::*: :*.*::***:******************************:*:*.*:**:******:*.********** :*:::**** :*:*.* *:*:: ::**** : *** **:****:**********::******* ********:**** *:****.**:*:**:*:**** :. : **::*** : .:: :*: **:**:*:**:* :", "identical_positions": 279, "similar_positions": 144, "identity": "51.67%" }, { "cls_id": "homologset.agr.RGD:620491", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UZZ6-1", "uniprot_id": "ST1D1_MOUSE", "id": "Q3UZZ6-1", "name": "Sulfotransferase 1 family member D1", "aln": "-----------------------------MDNKLDVFRRELVDVEGIPLFWSIAEHWSQVESFEARPDDILISTYPKSG--------TTWVSEILDLIYNNGDAEKCKRDAIYKRVPFMELIIPGIT--NGVEMLNNMP-SPRIVKTHLPVQLLPSSFWKNDCKIIYVARNAKDVVVSYYYFYQMAKIHPEPGTWEEFLEKFMAGQVSFGPWYDHVKSWWEKRKEYR-ILYLFYEDMKENPKCEIQKILKFLEKDIPEEILNKILYHSSFSVMKENPSANYTTMMKEEMDHS-----VSPFMRKGISGDWKNQFTVAQYEKFEEDYVKKMEDSTLKFRSEI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V9R3-1", "uniprot_id": "ST1D1_RAT", "id": "G3V9R3-1", "name": "Sulfotransferase 1 family member D1", "aln": "-----------------------------MDNKLDVFRRELVDVQGIPLFWSIAEQWSQVESFEARPDDILISTYPKSG--------TTWISEILDLIYNNGDAEKCKRDAIYRRVPFMELIIPGIT--NGVEMLNNMQ-SPRLVKTHLPVQLLPSSFWKNDCKMIYVARNAKDVAVSYYYFHQMAKMHPEPGTWEEFLEKFMAGQVSFGPWYDHVKGWWEKRKEYR-ILYLFYEDMKEDPKCEIQKVLKFLEKDIPEEVVNKILYHSSFSVMKANPSANYTTMMKEEMDQS-----VSPFMRKGISGDWKNQFTVAQYEKFEEDYVKKMEESTLKFRSEI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PQS2-1", "uniprot_id": "A0A8M9PQS2_DANRE", "id": "A0A8M9PQS2-1", "name": "Sulfotransferase", "aln": "---------------------MTDHEFPDVASMKPCIRPDMFDFEGVFLTRFFTDNWENVKNFQARPDDILIATYPKAGYSAIKNPRTTWVSYILDLLY-FGNDENQTSQPIVQRVPFLESCFQEFSTISGTEMADNLPTSPRLIKTHLPVQLVPKSFWEQNSRVVYVARNAKDNAVSYFHFDRMNMVQPEPGDWDSYLDKFMQGQNVFGSWFDHVSGWWQKKRSYPNMLYMFFEDLSEDTGREVNRLCSFLGLSTSVQEKEKITKGVQFDAMKQNTLINHVTIP--FLDCK-----ISPFMRKGKVGDWKSHFTVAQNERFDEVYKQKMKNSGVTFRTEI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1L8-1", "uniprot_id": "Q9W1L8_DROME", "id": "Q9W1L8-1", "name": "", "aln": "MPQSSFFAKSVPFEQIDKLAISGGYSSIFASSKPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCG--------TTWMQELAWLVINECDFETAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWMLPRQIWSKRPKIIYVYRNPKDAAIS-YFHHWRGMVG-YQGTKSDFMHSFIDGYVNFTPCWPHILDFWQLRHEPN-IFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVKEFESMKAAAGREVEEFRFVRRGVVGSHKDELTADIIREFDLWSDSNLRDFKLNMDDFANYSKFAST------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KF40-1", "uniprot_id": "A0A0B4KF40_DROME", "id": "A0A0B4KF40-1", "name": "", "aln": "---------------MNRVQVTP-------RSYPTNLIDKDWGNRKLFYTKDSENFLRLVHDMKLRDDDVWIVTLPKCG--------TTWMQELLWLLLNNCDFEGALAKDQELRTPFLEFGYSVFHDPNRSFGPIEDLKSPRLIKSHLSLALLPSKLWEGKNKVIYVSRNPLDSYVSRYYHGVSFGFN-YGKSLHQYFDEVLASDDFPTEFIEHAHEFYQLRNEPW-VFYTSFEMMKKDLRGVINDVSRFLNKPINDQQMEKLLKHLSFAEMKKNPTTNHLWELAQVQHEN-AGKEMHPFVRRGDVNGYKDELKPEQIEKANVRIQEVLAKNGVTLDELLLLKDQDWPCSGLCTQHSQTNSEAITLRNGPKAHQHQCSSACTRWLCVRVKVVKAESRGRTGPILMLMQGSRDAEMPTPPPQREAKNGKQATFIAGREVFTVLWERRISQDVNRGSCTMFAPHSLPVTSRLLLLVVTLLFCPVQAHLSKRSYSDQSVHGYMTERTCWWNEVCKEEFQSLFRCKCPQFSYCRSPGRYYNAYCSMTDTGYIWTQPNWDWGA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * .:: * **: * * **.* ***:. : *: : * * **:* : ***::*:**. ::* .:*. :::** **. * :* :.. . .::...: . * ::: :.. ::: :* :. : :. : ** : ::: .* *: *. *: *:*:* .. *..:. .. : . : . :.: ", "identical_positions": 44, "similar_positions": 81, "identity": "7.87%" }, { "cls_id": "homologset.agr.RGD:620492", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHK3-1", "uniprot_id": "S36A2_MOUSE", "id": "Q8BHK3-1", "name": "Proton-coupled amino acid transporter 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVTKSARSPQV-----------ATPLNLDL---PESAKKLQSQDPSP---------------------------------------------------------------------ANGSSSESS--KKTKGITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRL-NKPFMDYGDTVMHGLAFSPNAWLQNHAHWGRRVVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNETVVLTPTMDSRLYMLSFLPVLGLLVFVRNLRVLTIFSLLANISMLVSLVIIAQYI----IQEIPDASQLP--LVASWKTYPLFFGTAIFSFESIGVVLPLENKMKDARGFP---TILSLGMSIITTLYIAIGALGYLRFGDDIKASITLNLP-NCWLYQSVKLLYVVGILCTYALQFYVPAEIIIPLAVSQVSK-----------------------RWALPVDLSIRLALVCLTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVVTYYG----EGISPLTVTKDALISILGFMGFVVGTYQALDELIKSGNSPALSNSTMFIQ-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K415-1", "uniprot_id": "S36A2_RAT", "id": "Q8K415-1", "name": "Proton-coupled amino acid transporter 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVTKSAGSPQV-----------AATVKLDLVSFPESAKKVQSQDPNP---------------------------------------------------------------------VNGSSSESS--EKTKGITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRL-NKPFMDYGDTVMHGLASSPNTWLQSHAHWGRHAVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNETVVLTPTIDSRLYMLAFLPVLGLLVFIRNLRVLTIFSLLANVSMLVSLVIIGQYI----IQGIPDPSQLP--LVASWKTYPLFFGTAIFSFESIGVVLPLENKMKDARRFP---TILSLGMSIITTLYIAIGALGYLRFGDDIKASITLNLP-NCWLYQSVKLLYVVGILCTHALQFYVPAEIIIPLAVSQVSK-----------------------RWALPVDLSIRLALVCVTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVTTYYG----EGMSPLTITKDALISILGFMGFVVGTYQALDELIRSGNSLPLSNSTMFIQ-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q495M3-1", "uniprot_id": "S36A2_HUMAN", "id": "Q495M3-1", "name": "Proton-coupled amino acid transporter 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVTKSTEGPQG-----------AVAIKLDLMSPPESAKKLENKDSTF---------------------------------------------------------------------LDESPSESAGLKKTKGITVFQALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHILVKCAQRFCKRL-NKPFMDYGDTVMHGLEANPNAWLQNHAHWGRHIVSFFLIITQLGFCCVYIVFLADNLKQVVEAVNSTTNNCYSNETVILTPTMDSRLYMLSFLPFLVLLVLIRNLRILTIFSMLANISMLVSLVIIIQYI----TQEIPDPSRLP--LVASWKTYPLFFGTAIFSFESIGVVLPLENKMKNARHFP---AILSLGMSIVTSLYIGMAALGYLRFGDDIKASISLNLP-NCWLYQSVKLLYIAGILCTYALQFYVPAEIIIPFAISRVST-----------------------RWALPLDLSIRLVMVCLTCLLAILIPRLDLVISLVGSVSGTALALIIPPLLEVTTFYS----EGMSPLTIFKDALISILGFVGFVVGTYQALDELLKSEDSHPFSNSTTFVR-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VT04-1", "uniprot_id": "PATH_DROME", "id": "Q9VT04-1", "name": "Proton-coupled amino acid transporter-like protein pathetic", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MVNIVDSGSK-------HAPQEMEQFLP----------GEGKVMYKIQPRKSDTEQALAGN---------------------------------------------------------------------------DFDPFALRDNPHPTTDNETLTHLLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKCGHKLYYRT-RRTKMTFAEIAEAAFQKGP-KWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVASNFEQLISYWTGTA--------------VSLRMLICIMLVPLILIAWVPNLKYLAPVSMVANVFMGLGLGITFYYL----VQDLP-PVEER-ESVV-WSTLPQFFSITIFAMEAIGVVMPLENNMKTPQSFLGICGVLSQGMSGVTLIYMLLGFLGYLRYGSATGESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEIIWDG-IKEKCK----------------------KRPTLV-NYVLRTVLVTAAVVLAVAVPTIGPFMGLIGAFCFSILGLIFPVVIELIVHWES--GFGKYNWILWKNAIITLCGIGALVFGTQAAIKDIVKAYSNNENVGE----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PEU1-1", "uniprot_id": "M9PEU1_DROME", "id": "M9PEU1-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------MSTPENLNAPAGKPPLPPRREQLTEKGQSLSLSSFGGSAGNISGSGRKQHLSGAALARHKLKMSLKRGGPPPVATSGSGVMTTSLDQQKIPTVTAGYGENEKPKGGKGGQSKFIRSDMADVPVQQAAGSTLPLVISRKK----------------------------GDDSEDGNYNPFEHRKVEHPTSDLETFVHLLKGSLGSGILAMPMAFSHAGLWFGLVATFAVGTLCTYCVHILVKCAHILCRRR-KIPMMGFADVAEQAFLDGP-PALNRWSRFIRFMVNTFLVIDLLGCCCIYLVFVATNVEQVVRVYMETE--------------LSIRVWIMIVTAPLIFMCLVRNLKFLTPFSMIANILMFVGIVITFIYM----FSDIPAPVERP-GIVS-VTEWPLFFGTVIFALEGIGVVMSLENDMKNPSHFIGCPSVLNFGMGLVIALYTLVGFFGFLKYGPETQASITLNLPLEDKLAQSVKLMIAIAIFFTFTLQFYVPVTILWKG-LEHKIRP---------------------EKQNIS-EYGLRVFLVLLCGGIAVALPNLGPFISLIGAVCLSTLGMIVPATIELAVYHEDP-GYGRFNWRLWKNSGLILFGVVGFVAGTYVSIIEFHAEFSSGH--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTD7-1", "uniprot_id": "Q9VTD7_DROME", "id": "Q9VTD7-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MPVMTKNGHS-------NSAYVADHP--------------DKLELAEKGQKNKAVVAKDPD----------------------------------------------------------------------------YNPYHHRDVEHPTTNSETLFHLLKGSLGTGILAMPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRK-KMPSMNYPMVAETAMGEGP-KCFRVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADTS--------------IDVRLCMIIILLPLILINWVRNLKYLAPFSTLANAITMVSFGIICYYI----FREPVTTEGKD-AFGK-PSNFPLFFGTVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSITLNMPEHEVLSMCVKGMLAFAIYITHGLACYVAIDITWNDYVAKRLGA---------------------QRNALFWEYAVRTGLVLITFLLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKV-WLVLSNFVLIIVGILGLVIGTYTSLKEIVLTFSE----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLM3-1", "uniprot_id": "Q9VLM3_DROME", "id": "Q9VLM3-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------------------MEDLTPLTNLQQIPEGAPRKKKMTER------------QPLLLQSDASDYEGSRGSAARPVRSSPP------------DNTLVNVHSEDSLAASGSGDDEIG--------------------------------------------------------------------STDKSYNPTHHRDLEHPTSNFDTLVHLLKGNIGTGILAMPDAFKNAGLYVGLFGTMIMGAICTHCMHMLVNCSHELCRRF-QQPSLDFSEVAYCSFESGP-LGLRRYSMLARRIVTTFLFITQIGFCCVYFLFVALNIKDVMDHYYK----------------MPVQIYLLIMLGPMILLNLVRNLKYLTPVSLVAALLTVAGLAITFSYM----LVDLPDVHTVK-PVAT-WATLPLYFGTAIYAFEGIGVVLPLENNMRTPEDFGGTTGVLNTGMVIVACLYTAVGFFGYLKYGEHVEGSITLNLPQGDTLSQLVRISMAVAIFLSYTLQFYVPVNIVEPF-VRSHFDT---------------------TRAKDLSATVLRVVLVTFTFLLATCIPNLGSIISLVGAVSSSALALIAPPIIEVITFYNV--GYGRFNWMLWKDVLILIFGLCGFVFGTWASLAQILNDRTH----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4V5R4-1", "uniprot_id": "POLYP_DROME", "id": "Q4V5R4-1", "name": "Glutamate transporter polyphemus", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPKSQDQAP-------------NRDDPDLQTEPLTIAQSITSFYM--------------------------------------------------------------------------YNPYEKRSVEVPLTNCDAFISLLKCVIGTGILAMPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRR-RVPQVSMPEAVRIAYEEGP-KWINCFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEIGDHYIER---------------YNERYYVLVACLLLLPLFMIRRLKYLVPLNLISNFLLYAGFALIMYYL----FNGLPNINDRE-MVTPPVEWI-EFIAIAAFSLTAVGSMLVVEAHMAHPQSYLGLFGVLNLAVLFILLSNMFFGIIGYWRFGDNVHASITLNIPQDEILSQFIKVFIASGIFLSYPLNGFVVITVMFSDYENSEPR----------------------GRYRTLIEYVVRLLFLFLTGAVAIGVPNLAALTELEGAFSLSNLNLLCPALIDVFLNYN--VGYGRLMWKLIRDILLILIGLIFGIVGCTVALMQLIRDF---------------------QLTLNSM--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQF3-1", "uniprot_id": "Q8IQF3_DROME", "id": "Q8IQF3-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDKGG------------------------------------------------------------------------------------------------------------------FDPYENRNVAHPISDIGAFFSLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIICMIECSRRM-QIGYATYPVAMVYSFDQGP-RFFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAATLKQLVDFYWVV---------------ADLRIYIAVIALCLIPPFQIRKLKYLVPFNILASILIYTGFSLMMYYL----FVDLPPITERN-ILFGRIDKIPLFFGIALFSITSVGVMLAVEATMAKPRHYLGWFGILDRAILLVIISYVTFGLMGYWRYGDETAGSISLNIPTDEVLSQVAKGFIAAAIFLTYPLAGFVIIDIIMNHFWNKNGD----------------------LPNAALKESILRACTVVLICITAIIAPNLGPLLSLVGALTISLLNLVFPALIEICLYYPPEYNYGKLKWVLVKDIFYVIVGILILVQGTVFSIKDMISEWGGGDTTTGGPETTAEETTANMSATLTTALTAAPPDALRFRFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W056-1", "uniprot_id": "S36A_DROME", "id": "Q9W056-1", "name": "Proton-coupled amino acid transporter-like protein acs", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNDDIKT---------------VTVYPTTLELTTPTKSANGSNDD--------------------------------------------------------------------------YDPHQHRELKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILCKRQ-RVPYVSFSQAMNLGLKQGP-PWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFIAESIKQLVDEYLVV---------------WDVRIHMCIIIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYYI----FEELPPLSERD-PFVA-AGKLPTFFGTVLFALEAVGVILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFAITTWISYALQGYVTAHILWDKYLAKRFK----------------------ETRQTFYELIFRAIIVLLTFGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYT--EGYGPFRIKLIINLLLLCFGIFGGVVGTYVSILDIIAVYK-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTD5-1", "uniprot_id": "Q9VTD5_DROME", "id": "Q9VTD5-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRNTRRRRL-------------DQKLPFHQRLLGGVQNSFGSPLA--------------------------------------------------------------------------NEARLSSKKDNGMSDLEAFINVLKCGFGTGCLAMPYAFLNSGWLVGLICTFALGFFVLYAMHILLHHINNLGVQH-NMPMISYRKAVELSIRKGP-SIFHFLSKPFGYLVDILLCAYHFGVDCVYVVFIAKSLKHLGDMYLWV---------------WDERLYMALIASPLILTFLIRNLKSLVPFSIISNILLLTGYCVILNYL----FRDLPEFEHLH-AIQP-LRNFPIFFGTVLFSIESVGVILSLGRSMRKPESLMGTCGVLNQGMIVVISFYAVFGFFGYWRYGENTSNSILQNMPQNDILPKLATGIFALAIFFSYALQGYVTVDIIWRNYLEPELE----------------------DRYLRTVECLLRIALVIASVLVAIQYPDFGLLLSLVGSFCLAQLGLILPGIVDICLRYE--EDYGPGKIFLIRSMLFICMGLAGGVAGTVVTLQTLYARYPVVRG-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VX84-1", "uniprot_id": "Q9VX84_DROME", "id": "Q9VX84-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MDAEAPNQLEKNQTATVPRQETAE-------------GGSTGETAVGGAAAKVTK---EQDHD------------------------------------------------------------------------AEYHPP-------TSYLETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRDLKGDSVCADYAQTVEQCFENGP-SKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQAYDID---------------MNVHLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLYYA----LKDG-LPEVEERALWTNGSQLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMFAGSVGYMKWGEQVGGSLTLNLG-DTILAQAVKLMVSAGVLLGYPLQFFVAIQIMWPNAKQMCGIE---------------------GRS-LLGELGFRTFMVLVTLAIAEMVPALGLFISLIGALCSTALALVFPPVIELISRSE--LNKGPGIWICVKNLVILVLALLGFFTGSYESLKQIVKHFGEEEVH------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PHT8-1", "uniprot_id": "M9PHT8_DROME", "id": "M9PHT8-1", "name": "Amino acid transporter transmembrane domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MPKRDLTVLHRYFSGRLFPARTQQQQSDQKAIEAAGEMGRTLEI---------TGRQNDKSLEKNPERFTKNVTEKGAD------------------------------------------------------------------------PENGDPVRRRGHETSELEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERMLIRGSVLAVERTPGVDFLDYPETVEKCFEHGP-RPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQVLQQNGIV---------------ISMSMVMLITLLPAMIPSLMTNLKYISPVSLFANVALLFGLIATLTIA----FSDGPMPSVGDRHLFTGGAQLALFFGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSITLNLVVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSNNCT---------------------QKYPITSQVCLRFFMVMMTFGVALVVPKLNLFISLIGALCSTCLAFVIPVLIDFVTRAQ--VPKALGVWSYIKNILILTVAVLGIVTGTYQSIVEIVKEFK-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50944-1", "uniprot_id": "AVT4_YEAST", "id": "P50944-1", "name": "Vacuolar amino acid transporter 4", "aln": "MVTNNGDGEHLGIRRNGNLRHPSN-NMKIPRRAQSTVLNSNPFYSRKYSMSTLTPRDICRSVDSRVFVDMSSPNFQTLEDPHRDEIINSVRLNYLNSSKRSSVSHGNEAIPRVNPTKNSSASTIAAANVD------SDDDETNLSSAGGDITHDIYKLVKAEDPKRLRRPRSMENVTPKIEHHTKLSSASGLN-VPGGFRREFIVNKKRQEHQLNDSASSDFTSHESDSINQSSPSSNQDIDKVPFLTRNFLEFLYVFGHFAGESFEDDFIPDSSNMMIRGEDERSALLSRPDHMKVLPSAKG--TTSTKKVFLILLKSFIGTGVLFLPNAFHNGGLFFSVSMLAFFGIYSYWCYYILVQAKSSCGVSS---------------FGDIG---LKLYGPWMRIIILFSLVITQVGFSGAYMIFTAKNLQAFLDNVFHV-------------GVLPLSYLMVFQTIIFIPLSFIRNISKLSLPSLLANFFIMAGLVIVIIFTAKRLFFDLMGTPAMGVVYGLNADRWTLFIGTAIFAFEGIGLIIPVQDSMRNPEKFP---LVLALVILTATILFISIATLGYLAYGSNVQTVILLNLPQSNIFVNLIQLFYSIAIMLSTPLQLFPAIKIIENKFFPKFTKIYVKHDDLTTRVELRPNSGKLNWKIKWLKNFIRSIIVIIVVSIAYFGSDNLDKFVSVIGSLACIPLVYIYPSMLHLRGNSLPETKGEFWRFKPMLDTILIFFGIASMLYTSYQSIFGV----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36062-1", "uniprot_id": "AVT3_YEAST", "id": "P36062-1", "name": "Vacuolar amino acid transporter 3", "aln": "MNGKEVSSGSGRTQSNNNKKNNNGGSTGISHASGSPLTDGNGGNSNGNSRSRSRSRKSSGTTGGLLKKPPLLVNNEAVHASVPDASHTSCNNGTLEVSINNPEPHVVDAVARHLIRNPSNSLQLQGGDITRDLYKWTNDHPSSPSQYQYPSQPALSTSIPSQAPSFSNRKRSMSFSAASIASSSHLNNNSEANGNPLAAIGLAPAPMTHEEIRAPGGFRRSFIIQKRRKHNVDAPIPN-------FFTRNFIEFLTLYGHFAGEDLSEEEEEEEE---TEEEPEEEALETESTQLVSREHGRHPHKSSTVKAVLLLLKSFVGTGVLFLPKAFHNGGWGFSALCLLSCALISYGCFVSLITTKDKVGVDG---------------YGDMG---RILYGPKMKFAILSSIALSQIGFSAAYTVFTATNLQVFSENFFHLK-----------PGSISLATYIFAQVLIFVPLSLTRNIAKLSGTALIADLFILLGLVYVYVYS---IYYIAVNGVASDTMLMFNKADWSLFIGTAIFTFEGIGLLIPIQESMKHPKHFR---PSLSAVMCIVAVIFISCGLLCYAAFGSDVKTVVLLNFPQDTSYTLTVQLLYALAILLSTPLQLFPAIRILENWTFPSN------------------ASGKYNPKVKWLKNYFRCAIVVLTSILAWVGANDLDKFVSLVGSFACIPLIYIYPPLLHYKASILSGTS----RARLLLDLIVIVFGVAVMAYTSWQTIKMWSQ--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ..* .*.* : : .. .* . *: . : . * :: : ... . : .: : : . ::. . :: .:. :: : * . * : . . : :* : *: : : : : : . : *:. * * :. . .. :: ", "identical_positions": 13, "similar_positions": 65, "identity": "1.62%" }, { "cls_id": "homologset.agr.RGD:620494", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05507-1", "uniprot_id": "NU4LM_RAT", "id": "P05507-1", "name": "NADH-ubiquinone oxidoreductase chain 4L", "aln": "-MTSAFLNL-TMAFTLSLLGTFMFRSHLMSTLLCLEGMMLSLFVMTSTSTLNSNSMISMTIPITILVFAACEAAVGLALLVKISNTYGTDYVQNLNLLQC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03903-1", "uniprot_id": "NU4LM_MOUSE", "id": "P03903-1", "name": "NADH-ubiquinone oxidoreductase chain 4L", "aln": "-MPSTFFNL-TMAFSLSLLGTLMFRSHLMSTLLCLEGMVLSLFIMTSVTSLNSNSMSSMPIPITILVFAACEAAVGLALLVKVSNTYGTDYVQNLNLLQC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03901-1", "uniprot_id": "NU4LM_HUMAN", "id": "P03901-1", "name": "NADH-ubiquinone oxidoreductase chain 4L", "aln": "-MPLIYMNI-MLAFTISLLGMLVYRSHLMSSLLCLEGMMLSLFIMATLMTLNTHSLLANIVPIAMLVFAACEAAVGLALLVSISNTYGLDYVHNLNLLQC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18934-1", "uniprot_id": "NU4LM_DROME", "id": "P18934-1", "name": "NADH-ubiquinone oxidoreductase chain 4L", "aln": "MIMILYWSLPMILFILGLFCFVSNRKHLLSMLLSLEFIVLMLFFMLFIY-LNMLNYESY-FSMMFLTFSVCEGALGLSILVSMIRTHGNDYFQSFSIM--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: : * :.*: . *.**:* **.** ::* **.* ** . : ..: :*.*:.**.*:**::**.: .*:* **.:.:.:: ", "identical_positions": 29, "similar_positions": 39, "identity": "29.0%" }, { "cls_id": "homologset.agr.RGD:620495", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CBB9-1", "uniprot_id": "RSAD2_MOUSE", "id": "Q8CBB9-1", "name": "S-adenosylmethionine-dependent nucleotide dehydratase RSAD2", "aln": "MGMLVPTALAARLLSLFQQQLGSLWSGLAILFCWLRIALGWLDP-GKEQPQVRGEPEDTQETQEDGNSTQPTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70600-1", "uniprot_id": "RSAD2_RAT", "id": "O70600-1", "name": "S-adenosylmethionine-dependent nucleotide dehydratase RSAD2", "aln": "--MLVPTALAARLLSLFQQQLGSLWSGLAMLFCWLRIALGWPDP-GKGQPRVRGEPKETQETHEDPGSAQPTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGMEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGDYLDILAISCDSFDEQVNVLIGRGQGKKNHVENLQKLRKWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNEEFEAFLQRHKDVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSRSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WXG1-1", "uniprot_id": "RSAD2_HUMAN", "id": "Q8WXG1-1", "name": "S-adenosylmethionine-dependent nucleotide dehydratase RSAD2", "aln": "MWVLTPAAFAGKLLSVFRQPLSSLWRSLVPLFCWLRATFWLLATKRRKQQLVLRGPDETKEEEEDP--PLPTTPTSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKEAGMEKINFSGGEPFLQDRGEYLGKLVRFCKVELRLPSVSIVSNGSLIRERWFQNYGEYLDILAISCDSFDEEVNVLIGRGQGKKNHVENLQKLRRWCRDYRVAFKINSVINRFNVEEDMTEQIKALNPVRWKVFQCLLIEGENCGEDALREAERFVIGDEEFERFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCRKGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYIWSKADLKLDW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RH95-1", "uniprot_id": "RSAD2_DANRE", "id": "Q5RH95-1", "name": "S-adenosylmethionine-dependent nucleotide dehydratase RSAD2", "aln": "MVTSNQLGFARLLMQLCVKNVQSFF---LALLRWLSMQVSGAHVQQTPARKISR-PESRTSKQKEGSRAPFTTPSSVNYHFTRQCNYKCGFCFHTAKTSFVLPIEEAKRGLRLLKEAGMEKINFSGGEPFVHQKGSFLGELVLYCKQELQLPSVSIVSNGSLIRESWFQKYGDYLDILAISCDSFIEETNQLIGRAQGRKSHLDNLHKVRNWCREYKVAFKINSVINTYNVEEDMTEQITALNPVRWKVFQCLLIEGENAGENSLREAEKFVISDQQFQDFLERHQSIQCLVPESNQKMRDSYLILDEYMRFLDCREGRKDPSKSILDVGVEEAIKFSGFDEKMFLMRGGKYVWSKADMKLEW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* *:.: : : *:: *: ** . : *.. . .:: . *** ****************************:******* ***:**:***********::::*.:**:** :** ** *************** **:.**:************ *:.* ****.**:*.*::**:*:*.***:*:********** :**:***.*:*.**.****************.**::*****:*:*.:::*: **:**:.:.**********:*************:* ******:********************** *****:*****:**:*", "identical_positions": 233, "similar_positions": 72, "identity": "64.19%" }, { "cls_id": "homologset.agr.RGD:620496", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4V4-1", "uniprot_id": "CBPZ_MOUSE", "id": "Q8R4V4-1", "name": "Carboxypeptidase Z", "aln": "MPTMPLLLAALAALAVLALAARPSPSCSPGPDPSGKCQRLVYTHSATCVDLHLRTCADAAYNHTSFPTPLEHRSWEAVESSPEYMLLGVIHFLLEGQCNPDLRLLGCSVLAPRCEGGHTQRPCRHVCEGLREACQPAFDAIDMAWPYFLDCAQYFAPEEEGCYDPLEELRGELDVEEALPSGLPPTFIRFAHHSYAQMVRVLKRTAARCSQVAKTYSIGRSFEGKDLVVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREVLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLASTRGVRTDHIPISQYYWWGKVAPETKAIMKWIQTIPFVLSASLHGGDLVVSYPFDFSKNPHEKKMFSPTPDEKMFKLLARAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYGLWQQNKEPLLNFLEMVHRGIKGMVTDKYGKPVKNARILVKGIRHDVTTAPDGDYWRLLPPGSHIVIAQAPGYSKVMKRVTIPLRMKKAGRVDFILHPLATGPKNFLPGPSRALPRFQDPQREPTQM----DFEPPRARRQP-ASGSKPWWWAYFTSLSPYKPRWLLKY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54858-1", "uniprot_id": "CBPZ_RAT", "id": "O54858-1", "name": "Carboxypeptidase Z", "aln": "MPTTPLLLAALAALAALAVAAYP--SCSPGPDPSGKCQRLASTHSATCVDLHLRTCADAAYNHTSFPTPLEHRSWEAVEASPEYTLLGVLHFLLEGQCNPDLRLLGCSVLAPRCQGGHTQRPCRRVCEGLREACQPAFDAIDMAWPYFLDCTQYFAPEEEGCYDPLEQLRGELDVEEALPSGLPPTFIRFAHHSYAQMVRVLKRTAARCSQVAKTYSIGRSFEGKDLVVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREILIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLASTRGVRTDHIPISQYYWWGKVAPETKAIMKWIQTIPFVLSASLHGGDLVVSYPFDFSKHPHEEKMFSPTPDEKMFKLLARAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYGLWQHNKEPLLNFLEMVHRGIKGVVTDKYGKPVKNARILVKGIRHDVTTAPDGDYWRLLPPGSHIVIAQAPGYSKVMKRVTIPLRMKRAGRVDFILQPLGTGPKNFLPGPSRALPRSLDPQGAPAQL----DFEPPRARRQP-ASGSKPWWWAYFTSLSPHKPRWLLKY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66K79-1", "uniprot_id": "CBPZ_HUMAN", "id": "Q66K79-1", "name": "Carboxypeptidase Z", "aln": "---MPPPLPLLLLTVLVVAAARP--GCEFERNPAGECHRPPAADSATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGCAVLAPRCEGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGLPPTFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYILWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGMGPKNFIHGLRRTGP--HDPLGGASSLGEATEPDPLRARRQPSADGSKPWWWSYFTSLSTHRPRWLLKY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *. * . :. ** * .*. :*:*:*:* :.*******:****:*******:**. *:*****.**:*.** **.*:* ***************:******:** .:****::******.****************** :**: *:********:*** *:.:**************:***********:***:**::**:********:*::*:*********************************:*******************************************************************************.***.*:*****.*:****************:**************************:*:*:***************:********************************************************************** ***:***.****:* *******:****:********* *******:*************** **********:**:*:* ** ***:********:**. *****: * *: * ** .:.: : :* ****** *.*******:******.::*******", "identical_positions": 525, "similar_positions": 82, "identity": "79.67%" }, { "cls_id": "homologset.agr.RGD:620497", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0CX44-1", "uniprot_id": "RL1B_YEAST", "id": "P0CX44-1", "name": "Large ribosomal subunit protein uL1B", "aln": "-MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX43-1", "uniprot_id": "RL1A_YEAST", "id": "P0CX43-1", "name": "Large ribosomal subunit protein uL1A", "aln": "-MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53026-1", "uniprot_id": "RL10A_MOUSE", "id": "P53026-1", "name": "Large ribosomal subunit protein uL1", "aln": "MSSKVSRDTLYEAVREVLHG-NQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDERKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62907-1", "uniprot_id": "RL10A_RAT", "id": "P62907-1", "name": "Large ribosomal subunit protein uL1", "aln": "MSSKVSRDTLYEAVREVLHG-NQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62906-1", "uniprot_id": "RL10A_HUMAN", "id": "P62906-1", "name": "Large ribosomal subunit protein uL1", "aln": "MSSKVSRDTLYEAVREVLHG-NQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PC69-1", "uniprot_id": "RL10A_DANRE", "id": "Q6PC69-1", "name": "Large ribosomal subunit protein uL1", "aln": "-MSKVSRDTLYEAVKEVQAG-SRRKKRKFLETVELQISLKNYDPQKDKRFSGTVRLKTTPRPKFSVCVLGDQQHCDEAKAAELPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENLGTKVDEVKSTIKFQMKKVLCLAVAVGHVKMSEEELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTP4-1", "uniprot_id": "R10AB_DROME", "id": "Q9VTP4-1", "name": "Large ribosomal subunit protein uL1", "aln": "MASKVSRDTLYEGVNGLLEA-SAKKKRGFLETVELQIGLKNYDPQKDKRFSGTVKLKHIPRPKMKVCILGDQQHCDEAKANNVDFMDAEALKKLNKNKKLVKKLAKSYDAFLASESLIKQIPRLLGPGLNKAGKFPALLSHQESMIGKIEEVKSTIKFQMKKVLCLSVAVGHVGMKSDELAQNVNLSINFLVSLLKKNWQNVRSLHVKSSMGPPQRLY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFE0-1", "uniprot_id": "Q9VFE0_DROME", "id": "Q9VFE0-1", "name": "Large ribosomal subunit protein uL1", "aln": "MVSKVSRDTIYVAVKNILLN-SQAKGPDCLETVELQIGLRDYDPDKCKRFHGSVLLHHLAVPQLKVCVFGDQEHCYKAKAIGVDCLDVEALKKLNKDPKLTKKLSKAYDVFLASESIIKQIPRLLGPGLTNAGKFLTPLARGESMSSKIK-ILSTKKKHMKRMECLSVNVGHVGMHPEELARNIAISINFLVSLLKDNWQNVRSLHIKSSLGVPHQLY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:: . : *. : . * *******:.*::***:: *** *:: * . *::.:*::** . . *: : :. : ******: ** ***:* *:.*:*** :***:**:*** *.:**** : ::: :.: *: : ** * ::*:: **:* **:* * : *. :: :::**:*****.***** :* :**::* . :**", "identical_positions": 86, "similar_positions": 69, "identity": "39.45%" }, { "cls_id": "homologset.agr.RGD:620499", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET62-1", "uniprot_id": "IMPG1_RAT", "id": "Q9ET62-1", "name": "Interphotoreceptor matrix proteoglycan 1", "aln": "MNLEIKHAILVLWIFLQVQGIKDTSTKTHSSGTKNIDKAPRIETTESTSAVHKASTMKRLFAVAKLRNKRSALFP-AVNICPRESLRQILESLQEYYRLRVCQEIVWEAYRIFLDRVPDTEEYQDWVSLCQKETFCLFDIGKNFSNSQEHLDLLQQRIFQRS--------FSGRKDDMSPIEILGVPTTAPVLPIDVSSMSLRPFPLPPDDTDLKEVTIKDIQTPIAIRRAELESKPEPTHVTEISSEE---------------KVEFSISLPNHRFKAELTNSRSPYYQELVGQSQLQLQKIFKKLPGFGEIRVLGFRPKKEEDGSSSTEIQLMAIFKRDHAESKGPESDLLSLDSNKIERERIHHGAIE-DKQPE-----AYLTAADLKKLIIRLLDGDQPLVGGTVPFSDEVTEPL--FRPVTQSELPKPLTDVTEDVTLSPELPFSEP-------------RLESVDIYGPYLP-----DSSWSRPVTASTSGVGNLPSFTP-SIFALDDQSSPPLMATGPTAFIPTLTLPISDYSTVRQWPLEVSHWPESSSDRELSTTSSHDTIRDLDEMDVSDTPALSEIAELSGYDS--------APDRFLEMTTPIP---------------------------------------------------TLQYVTXSSETIAAKGHELVVFFSLRVANMPFSYDLFNKSSLEYQALEQRFTDL------------------------------LVPYLRSNLTGFKQLEILSFRNGSVIVNSKVRFAKAVPYNLTQAVRGVLEDLRSTAAQELNLEIESYSLDIEPADQADPCKFLDCGKFAQCIKNELTEEAECRCRQGHESHG-----TLEYQELNLCPPG-KTCEASQGQATPCRPPD------------------------------------------------------------------------------------------------------------------------------HSTNQARQPSVKKLQR-QQNKVVKKRNSELSATDFEELDDQDWEGN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1W8-1", "uniprot_id": "IMPG1_MOUSE", "id": "Q8R1W8-1", "name": "Interphotoreceptor matrix proteoglycan 1", "aln": "MNLQIKHAIFVLGIFLQVQGIKDTSIKIFSSEIKNIDKTPRIETIESTSTVHKVSTMKRIFDLPKLRTKRSALFP-AANICPQESLRQILASLQEYYRLRVCQEVVWEAYRIFLDRIPDTEEYQDWVSLCQKETFCLFDIGKNFSNSQEHLDLLQQRIKQRS--------FPGRKDETASMETLEAPTEAPVVPTDVSRMSLGPFPLPSDDTDLKEILSVTLKD---IQKPTTESKTEPIHVSEFSSEE---------------KVEFSISLPNHRFKAELTNSGSPYYQELVGQSQLQLQKIFKKLPGFGEIRVLGFRPKKEEDGSSSTEIQLMAIFKRDHAEAKSPDSHLLSLDSNKIESERIHHGVIE-DKQPE-----TYLTATDLKKLIIQLLDGDLSLVEGKIPFGDEVTGTL--FRPVTEPDLPKPLADVTEDATLSPELPFVEP-------------RLEAVDREGSELPGMSSKDSSWSPPVSASISRSENLPSFTP-SIFSLDAQSPPPLMTTGPTALIPKPTLPTIDYSTIRQLPLESSHWPASSSDRELIT-SSHDTIRDLDGMDVSDTPALSEISELSGYDS--------ASGQFLEMTTPIP---------------------------------------------------TVRFITTSSETIATKGQELVVFFSLRVANMPFSYDLFNKSSLEYQALEQRFTDL------------------------------LVPYLRSNLTGFKQLEILSFRNGSVIVNSKVRFAKAVPYNLTQAVRGVLEDLRSTAAQGLNLEIESYSLDIEPADQADPCKLLDCGKFAQCVKNEWTEEAECRCRQGHESHG-----TLDYQTLNLCPPG-KTCVAGREQATPCRPPD------------------------------------------------------------------------------------------------------------------------------HSTNQAQEPGVKKLR--QQNKVVKKRNSKLSAIGFEEFEDQDWEGN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q17R60-1", "uniprot_id": "IMPG1_HUMAN", "id": "Q17R60-1", "name": "Interphotoreceptor matrix proteoglycan 1", "aln": "MYLETRRAIFVFWIFLQVQGTKDISINIYHSETKDIDNPPRNETTESTEKMYKMSTMRRIFDLAKHRTKRSAFFPTGVKVCPQESMKQILDSLQAYYRLRVCQEAVWEAYRIFLDRIPDTGEYQDWVSICQQETFCLFDIGKNFSNSQEHLDLLQQRIKQRS--------FPDRKDEISAEKTLGEPGETIVISTDVANVSLGPFPLTPDDTLLNEILDNTLND---TKMPTTERETE----FAVLEEQ---------------RVELSVSLVNQKFKAELADSQSPYYQELAGKSQLQMQKIFKKLPGFKKIHVLGFRPKKEKDGSSSTEMQLTAIFKRHSAEAKSPASDLLSFDSNKIESEEVYHGTMEEDKQPE-----IYLTATDLKRLISKALEEEQSLDVGTIQFTDEIAGSLPAFGPDTQSELPTSFAVITEDATLSPELPPVEP-------------QLETVDGAEHGLP-----DTSWSPPAMASTSLSEAPPFFMASSIFSLTDQGTTDTMATDQTMLVPGLTIPTSDYSAISQLALGISHPPASSDD-SRSSAGGEDMVRHLDEMDLSDTPAPSEVPELSEYVS--------VPDHFLEDTTPVS---------------------------------------------------ALQYITTSSMTIAPKGRELVVFFSLRVANMAFSNDLFNKSSLEYRALEQQFTQL------------------------------LVPYLRSNLTGFKQLEILNFRNGSVIVNSKMKFAKSVPYNLTKAVHGVLEDFRSAAAQQLHLEIDSYSLNIEPADQADPCKFLACGEFAQCVKNERTEEAECRCKPGYDSQG-----SLDGLEPGLCGPGTKECEVLQGKGAPCRLPD------------------------------------------------------------------------------------------------------------------------------HSENQAYKTSVKKFQNQQNNKVISKRNSELLTVEYEEFNHQDWEGN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJ68-1", "uniprot_id": "A0A8M3AJ68_DANRE", "id": "A0A8M3AJ68-1", "name": "Interphotoreceptor matrix proteoglycan 1", "aln": "MPLKTGLFLILFLFTLQATGIKEPTADDLVFKIRNVKYRHFLETPQQNRQLTDG---RDSLSLDRHRAKRSALFGTGVKVCPQESMAEVITSHKAYYKLRVCQEAVWEAFRIFLDRVPDTMEYQQWVYACQRDSLCIEDLARNFSSTQEHLDIVASRVNQLDEQDRALTPAPGEKCSKSPAELFIMESDSETGAPDVVPQRPVEHIVRFSVTVVDPVYSALLRDPASPQYEDLTRNLHDQMLHAFDKLPGFKEIQVLGFRAGGVEASYAVVFETDGTQAIGDTDSTDEYGIQGVLKGMVVKVLNEDTSLPVDVRSLTFEPDSSTADGQENLNSGTQISEKSRVLPGEMSTPSTKADSDDSIVPSGSLGIPFKDVDPDRTWDLGVGTERSFIQKVPDILSHATALPAGAELISSPSLEGSKAASLITEDTLATKGSQGSTTVDYLSKMPEDQEGAGNEIVSTAAPLDLRSFEAEKASTLAQSEMDFDSTPETTPAEATSSISTLITPTEQAKGAIFQVDDTIGPSESLETSNVGIPSYPTSPVDSPAIPTSIDPSDHLEPPSVSVTVDTLHLKVTPAGPTTPEPILPATILSQLTPTEDLISHPTPNNFLDEQEQVLRTASSPPHEGGADDEGETKQDVEQSDEEDETLDLGSGFPSEIDENPQSSARPLGYVTTPSIMASNQAKELVVFFSLRVTNMMFSEDLFNKSSPEYKSLENTFLELRQFSEPSDSTNPEASSQVPDREQKTLASIPLLPYLQSNLTGFKELEILNFKNGSVVVNSKMTLNKPVPYNVTETVQCVLEDFCNAASKRLNMEIDSQSVDVEAADHADPCKFMACNEFSRCVVNTLTEEGECLCDPGYSTVDGDPCTSICDLEPEYCLNG-GLCEIIPGHGATCRCPVGKFWHYHGERCSELVSVPVDPVLFVTCLVGSLSVVCAVIGILIFINKKCIRTRKSMRLVRPQSAFPFGNTMRVNPVFENDDGVLTHVSSILCPMSSDSASLQQSGQGTFRSIESLQLSIEIPRQLYTRRSEKLMSEMVDFHQYIPHNEMRRTSSRSSCCFLRSPDSEGFEVTVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: :::: : **. * *: : . :::. ** :.. : . : : : : * ****:* ..::**:**: ::: * : **:****** ****:******:*** ***:** **::::*: *:.:***.:*****:: .*: * . ...* . :. : : : . . ** . : . * :. : :. : : . . . ... :: : .. :* . : * . : :: : :. . .:: * *.*... ..... . * :: . . : . **:. * * :*: * .: : : *. .* * : . *: *.. : : . .::* : *.:.: * . : . .: : . : . . : .. : . :* *.: . .: * * . : : . .: . : . . . ** . ....**: : .: ::* .* : :.:**********:** ** ******* **::**: * :* *:***:*******:****.*:****:****: : *.****:*::*: ****: .:*:: *::**:* *:::*.**:*****:: *.:*::*: * ***.** * *:.: . :: * * * :.:.** * .: . : .:: :: : : .*. .. : :.:* . ", "identical_positions": 188, "similar_positions": 258, "identity": "17.52%" }, { "cls_id": "homologset.agr.RGD:62050", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P27768-1", "uniprot_id": "TNNI2_RAT", "id": "P27768-1", "name": "Troponin I, fast skeletal muscle", "aln": "------------------------------------------------------------------------------------------MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRRESEKQNYLSEHC--PPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVKVQKSSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKK-EDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13412-1", "uniprot_id": "TNNI2_MOUSE", "id": "P13412-1", "name": "Troponin I, fast skeletal muscle", "aln": "------------------------------------------------------------------------------------------MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRRESEKENYLSEHC--PPLHIPGSMSEVQELCKQLHAKIDVAEEEKYDMEVKVQKSSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKK-EDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48788-1", "uniprot_id": "TNNI2_HUMAN", "id": "P48788-1", "name": "Troponin I, fast skeletal muscle", "aln": "------------------------------------------------------------------------------------------MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHC--PPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKK-EDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BA47-1", "uniprot_id": "A0A8M2BA47_DANRE", "id": "A0A8M2BA47-1", "name": "", "aln": "--------------------------------------------------------------------------------------------MFMNRKKMTSSRRHHLKSLVLSIAFNLLDAEAKQHIADKESHMSENC--PALDLPGSVQELQDLCKKLHQQIDKVDEERYDMEAKVAKADKEIEDLKIKVIDLKGKFKKPALKKVRMSADAMLQALLGSKHKVSMDLRANLKQVKK-EVKEESV--EQVGDWRKNIEDKAGMDGRKKMFESEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QCC0-1", "uniprot_id": "F1QCC0_DANRE", "id": "F1QCC0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------MSEKKMTSSRRHHLKSLLLQIAHGLLEEEAAAAEEEKQRYMEENC--PSLSLPGSLQELQELCRKMHQQIDMVDEQRYDMETKVAKSDKEIEDLKIKVQDLKGKFKKPVLKKVRMSADAMLQALLGSKHKVSLDLRANLKQVKK-EVKEEEK--EAVGDWRKNIEDKAGMDGRKKMFESEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32THC7-1", "uniprot_id": "A0AB32THC7_DANRE", "id": "A0AB32THC7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------MSEKRLSSSKKHSLKSMMLQVAKDLLEAEAVEKKEERKRYMEEHC--PAFSCPSSKQELEEFCRKLHEKIEVIDEERYVLEHKATMVVNEVKDLNIKIVDLKGKFKKPPLKKVRMSADAMLQALLGSKHKVSMDLRANLKQVKK-EVKEENKDLRDVGDWRKNIEDKTGMGGRKKMFESEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36188-1", "uniprot_id": "TNNI_DROME", "id": "P36188-1", "name": "Troponin I", "aln": "MADDEKKAAAPAAAPAAAAKPAAPAAAPAANGKAAPAANGKAAPAAAAAPAGPPKDPNDPKVKAEEAKKAKQAEIERKRAEVRKRMEEASKAKKAKKGFMTPERKKKLRLLLRKKAAEELKKEQERKAAERRRIIEERCGSPRNLSDASEGELQEICEEYYERMYICEGQKWDLEYEVRKKDWEINDLNAQVNDLRGKFVKPALKKVSKYENKFAKLQK---KAAEFNFRNQLKVVKKKEFTLEEEEKEKKPDWSK---GKPGDAKVKEEVEAEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . ::: *: :: . * *. * ::. : *.* * .* *::::*.: : :: : ::: :* .. *::*:: :: **:*** :* *::* : : : : . :::* :** *** * . :. . ** * *.* *: .*:*:", "identical_positions": 36, "similar_positions": 61, "identity": "13.09%" }, { "cls_id": "homologset.agr.RGD:620500", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1F2-1", "uniprot_id": "A0A0G2K1F2_RAT", "id": "A0A0G2K1F2-1", "name": "acetyl-CoA carboxylase", "aln": "MVLLLFLTCLVFSCLTISWLKIWG-KMTDSKPLSNSKVDASLLSSKEESFSASDQSEEHG----DCSCPLTTPDQEELASHGGPVDASQQRNSVPSSHQKPPRNPLSSNDTCSSPELQTNRVAAPGSEVPEANGLPFPARPQTQRTGSPTREDKKQAHIKRQLMTSFILGSLDDNSSDEDPSASSF--------------QTSSRKGSRASLGTLSQEAALNTADPESHTPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGNRVIETVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLCKHE--IAFLGPPSEAMWALGDKISSTIVAQTLQIPTLPWSGSGLTVEWTEDSQHQGKCISVPEDVYEQGCVRDVDEGLQAAEKVGFPLMIKASEGGGGKGIRRAESAEDFPMLFRQVQSEIPGSPIFLMKLAQNARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAAPAVFEFMEQCAVLLAKTVGYVSAGTVEYLYSQ-DGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPVSFETP-------LSPPIARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLVNLLETESFQNNDIDTGWLDHLIAQRVQAE-KPDIMLGVVCGALNVADAMFRTCMTEFLHSLERGQVLPADSLLNIVDVELIYGGIKYVLKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLMQYTVEDGQHVEVGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCVVAKLELDDPSKVHAAQPFTGELPAQQTLPILGERLHQVFHSVLENLTNVMNGYCLPEPFFSMKLKDWVEKLMMTLRHPSLPLLELQEIMTSVAGRIPVPVEKAVRRVMAQYASNITSVLCQFPSQQCWASGMLGKHSTTELQPELLKIATILDCHAATLQRKVDREAFFMNTQSIVQLIQRYRSGTRGYMKAVVLDLLRRYLNVEHHFQQA--HYDKCVINLREQFKPDMTRVLDCIFSHSQVAKKNQLVTMLIDE---LCGPDPTLSEELTSILKELTQLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN--------LKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFQFMLPSSHPN----------------------RMAMPINVSD--PDLLRHSKELFMDSGFSPLCQRMGAMVAFRRFEEFTRNFDEVISCFANVPTDTPLFSKACTSLYSEEDSKPS-----------------FFLSQSLQEEPIHILNVAIQCADHMEDERLVPVFRAFVQSKKHILVDYGLRRITFLIAQER-EFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNN-TSVRTDCNHIFLNFVPTVIMDPLKIEESVRAMVMRYGSRLWKLRVLQAEVKINIRQTTSDCAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGSLHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPEKYP---------KDILTYTELVLDSQGQLVEMNRLPGCNEVGMVVFKMRFKTPEYPEGRDTIVIGNDITFQIGSFGIGEDFLYLRASEMARTEGIPQIYLAANSGARMGLSEEIKQIFQVAWVDPEDPYKGFRYLYLTPQDYTQISSQ---NSVHCKHIEDEGESRYVIVDVIGKDSSLGVENLRGSGMIAGEASLAYEKNVTISMVTCRAIGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHTNGVSHVTVPDDFEGVCTILEWLSYIPKDNQSPVPIITPSDPIDREIEFTPT-KAPYDPRWLLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRSVEVAVPADPANLDSEAKIIQQAGQVWFPDSAFKTAQVIRDFN-QEHLPLMIFANWRGFSGGMKDMYEQMLKFGAYIVDSLRLFKQPVLIYIPPGAELRGGAWVVLDSSINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLVKTIRRIDPVCKKLLGQLGTAQLPDK--DRKELESQLKAREDLLLPIYHQVAVQFADLHDTPGHMLEKGIISDVLEWKTTRTYFYWRLRRLLLEAQVKQEILRASPELSHEHTQSMLRRWFVETEGAVKAYLWDSNQVVVQWLEQHWSARDNLRSTIRENINYLKRDSVLKTIQSLVQEHPEATMDCVAYLSQHLTPAEQMQVVQLLSTTESPASH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q4Z2-1", "uniprot_id": "ACACB_MOUSE", "id": "E9Q4Z2-1", "name": "Acetyl-CoA carboxylase 2", "aln": "MVLLLFLTCLVFSCLTFSWLKIWG-KMTDSKPLTNSKVEANLLSS-EESLSASELSGEQ----------LQEHGDHSCLSYRGPRDASQQRNSLPSSCQRPPRNPLSSNDTWPSPELQTNWTAAPGPEVPDANGLSFPARPPSQRTVSPSREDRKQAHIKRQLMTSFILGSLDDNSSDEDPSAGSF--------------QNSSRKSSRASLGTLSQEAALNTSDPESHAPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGNRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLCKHE--IAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVEWTEDSRHQGKCISVPEDVYEQGCVKDVDEGLQAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPMLFRQVQSEIPGSPIFLMKLAQNARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAAPAVFEFMEQCAVLLAKMVGYVSAGTVEYLYSQ-DGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPIPFETP-------LSPPIARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLVNLLETESFQNNDIDTGWLDHLIAQRVQAE-KPDIMLGVVCGALNVADAMFRTCMTEFLHSLERGQVLPADSLLNIVDVELIYGGIKYALKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLMQYTVEDGDHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGVILEAGCVVARLELDDPSKVHAAQPFTGELPAQQTLPILGEKLHQVFHGVLENLTNVMSGYCLPEPFFSMKLKDWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQ---------------------QIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRKYLNVEHHFQQA--HYDKCVINLREQFKPDMTQVLDCIFSHSQVAKKNQLVTMLIDE---LCGPDPTLSDELTSILCELTQLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN--------LKKLILSETTIFDVLPTFFYHENKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFQFMLPSSHPN----------------------RMAVPISVSN--PDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEEFTRNFDEVISCFANVQTDTLLFSKACTSLYSEEDSK------------------------SLREEPIHILNVAIQCADHMEDEALVPVFRAFVQSKKHILVDYGLRRITFLVAQER-EFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNN-TSVRTDCNHIFLNFVPTVIMDPLKIEESVRDMVMRYGSRLWKLRVLQAEVKINIRQTTSDSAIPIRLFITNESGYYLDISLYREVTDSRSGNIMFHSFGNKQGSLHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPEKYP---------KDILTYTELVLDSQGQLVEMNRLPGCNEVGMVAFKMRFKTPEYPEGRDAVVIGNDITFQIGSFGIGEDFLYLRASEMARTEGIPQIYLAANSGARMGLAEEIKQIFQVAWVDPEDPHKGFRYLYLTPQDYTQISSQ---NSVHCKHIEDEGESRYVIVDVIGKDANLGVENLRGSGMIAGEASLAYEKTVTISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHTNGVSHVTVPDDFEGVCTILEWLSFIPKDNRSPVPITTPSDPIDREIEFTPT-KAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQVIRDFN-KERLPLMIFANWRGFSGGMKDMYEQMLKFGAYIVDGLRLYEQPILIYIPPCAELRGGSWVVLDSTINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLVKTIRRIDPVCKKLVGQLGKAQLPDK--DRKELEGQLKAREELLLPIYHQVAVQFADLHDTPGHMLEKGIISDVLEWKTARTFFYWRLRRLLLEAQVKQEILRASPELNHEHTQSMLRRWFVETEGAVKAYLWDSNQVVVQWLEQHWSAKDGLRSTIRENINYLKRDSVLKTIQSLVQEHPEVIMDCVAYLSQHLTPAERIQVAQLLSTTESPASS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00763-1", "uniprot_id": "ACACB_HUMAN", "id": "O00763-1", "name": "Acetyl-CoA carboxylase 2", "aln": "MVLLLCLSCLIFSCLTFSWLKIWG-KMTDSKPITKSKSEANLIPS-QEPFPASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSVAGSS--------------RESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNG--VAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQ-DGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETP-------SNPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAE-KPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIKLKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQ---------------------QIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRVEHHFQQA--HYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDE---LCGPDPSLSDELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN--------LKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPN----------------------RMTVPISITN--PDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFANVPKDTPLFSEARTSLYSEDDCK------------------------SLREEPIHILNVSIQCADHLEDEALVPILRTFVQSKKNILVDYGLRRITFLIAQEK-EFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNN-TSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYP---------KDILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLYLTPQDYTRISSL---NSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPS-RAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFN-REKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDK--DRKDLEGRLKAREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PKW2-1", "uniprot_id": "A0A8M9PKW2_DANRE", "id": "A0A8M9PKW2-1", "name": "acetyl-CoA carboxylase", "aln": "--------------------------MPSQTPISDCAG------------------------------------EHSPPMDPGLSSTSPRNEGIPPSATSDPTD-------------QSNITVS-----------HIESHRPRFGSGAQAKEKLK-----------FILGASEDNSSDDEPLVKNQ--------------TTTHQPKNTETLNAEPTASSEMPPTPVPSTG-LRPSMSGPHLLKKGKEHRKMEVHRDFTVASPAEFVTRFGGNRIIDKVLIANNGIAAVKCMRSIRRWSYEMFRNERTIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVEMIVDIAKRIPVQAVWAGWGHASENPKLPELLHKSG--ICFLGPSSKAMWALGDKVASSIVAQSAGIPTLPWSGTGLSVEWAEEEQRQGRLISVPPELYVQGCVKDVDEGLASAEKIGYPVVIKASEGGGGKGIRKVESSEDFPSLFRQVQAEVPGSPIFIMQLAEHARHLEVQILADQYGNAISLFGRDCSIQRRHQKIIEEAPASIASTITFEQMEQYAVRLAKMVGYVSAGTVEYLFSE-DGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGIPLYRIKDIRVLFGEAPWGDTTINFESP-------ECMPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVGATGGLHEFADSQFGHCFSWGENREEAISNMVVAMKELSIRGDFRTTVEYLIKLLETESFRNNDIDTGWLDHLIADKVQAE-RPDTMLGVVCGALQVADASFRESMSDFLHSLERGQVLPAASLVNTVNVDLIYDGVKYCLKVARQSPTTYVIIMNDSDIEVDVHRLSDGGLLLSYGGSSYTTYMKEEIDRYRVTVGNKTCVFEKERDPTVLRSPSAGKLLQYVVTDGSHVSASQPYAEIEVMKMVMTLHVQHSGCIRFLKRPGTVLEPGCIVALMDLDDPSCIHQVKPNTEPLPAQEPLPMVGERLHQVFHNVLENLVKIMDGYCLPEPYFSQKLKNWVDTLMKTLRDPSLPLLELQEIMTSVAGRIPVTVEKAIRKVMAQYASNITSVLCQFPSQ---------------------RIANILDSHAATLQRKADREIFFMNTQSIVQLVQRYRSGIRGYMKSVVLDLLKHYLQVEMQFQQA--HYDKCVINLREQYKPDMTPVLECIFSHAQVSKKNILVTMLIDQ---LCGRDPMLADELMVILDELTQLSKMENSKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN--------LKKLILSETSIFDVLPSFFYHNNRVVCMAALEVYVRRAYIAYELNSLQHHQLQDGTCAVDFQFMLPSSHPNREPNATVSQHMPKSTGSSPTLNRLTLPVNDSGEFPAMRRQGSELFLEGALSPPCQRMGAMVAFHSFDHFKRCFDEVICRFVDPLCESSLFFDGCSTFCDGESCK------------------------NMKENPIHIINVSIKQADTEDDDALVTAFTAFAHSKKSLLYDYGIRRVTFLVAQKR-EFPKYFTFRARDEFHEDRIYRNLEPALAFQLELNRMRNFDLKAVPCAHHRMQLYLGAARVEEGAEVTDYRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFSN-TPTRTDCNHIFLNFVPTVIMDPYKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTTTGDVIPIRLFLTNESGYYLDISLYKEVNDPSSGQIMFQSYGDKQGPLNGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGPGDSYP---------KDVLMCNELVLDSQGNLVQMNRLPGDNEVGMVAFRMRMKTPEYPEGRDIIVICNDITHMIGSFGPQEDQLFMRASELARAEGIPRIYISANSGARIGLAEEIRHMFQVAWIDPEDPYKGFKYLYLTPQDYTRISSS---NSVHCHHVEEGGESRYILTDIIGKEEGIGVENLRGSGTIAGETSQAYKEIITISMVTCRAIGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHNNGVTHSTVPDDFEGVLTILQWLSYMPKSNQSPVPIKPATDPVDREIDFVPT-KAPYDPRWLLCGRPHPTVKGAWQSGFFDHGSFLEIMATWAQTVVVGRARLGGIPLGVIAVETRTVELAIPADPANLDSEAKLLQQAGQVWFPDSAYKTAQAIEDFN-REKLPLMVFANWRGFSGGMKDMYDQVLKFGSYIVDALREFSQPVLVYIPPNAELRGGSWVVIDPTINLQHMELYADRESRGGVLEAEGTVEIKFRKKDLLKTMRRIDPVYSRLAEQLGKPDLPSQ--ERKDLEAKLKSREEFLLPIYHQVAVQFVDLHDTPGRMQEKGVITDILDWKTARSFFYWRLRRLLLEEVVKKEIMQANQDLSNGHIQSMLRRWFVETEGAVKAYLWDNNKVVVEWLENNLSQQDGTRSVIRENIKCIKRDYALKHIRSLVQANPEVTMDCIIHMAQNITPSQRAKVCHLLATMDNSTTS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z784-1", "uniprot_id": "A1Z784_DROME", "id": "A1Z784-1", "name": "", "aln": "--MLITILGTLAAFLAFLLTLIFGRGQKRSKPVQSSAATSATTATTGDSDNGNTNHNSS---------VIAATATATTTSSKPPIAPAAPPSAVKASDKRFPKACIKKVQFSSESLRSDVDELCDQLKDSALSNLSNDNIRIACHQNNNNSSINKNQNNNSIDISISISKMSETNESNDTAAQSAEGERPSFLVGDEIDERAAEAGEACDEFPLKMQNDVRQNGDISERRKRLRPSMSRGTGLGQDRHQ-----DRDFHIATTEEFVKRFGGTRVINKVLIANNGIAAVKCMRSIRRWAYEMFKNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGSNNNNYANVELIVDIALRTQVQAVWAGWGHASENPKLPELLHKEG--LVFLGPPERAMWALGDKVASSIVAQTAEIPTLPWSGSDLKAQYS------GKKIKISSELFARGCVTNVEQGLAAVNKIGFPVMIKASEGGGGKGIRRVDTTEEFPGLFRQVQAEVPGSPIFVMKLARGARHLEVQLLADQYGNAISLFGRDCSIQRRHQKIIEEAPAIVAQPEVFEDMEKAAVRLAKMVGYVSAGTVEYLYDP-EGRYFFLELNPRLQVEHPCTEMVADVNLPAAQLQIGMGIPLYRLKDIRLLYGESPWGSSVIDFENP-------PNKPRPSGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAASGGLHEFADSQFGHCFSWGENRQQARENLVIALKELSIRGDFRTTVEYLITLLETNRFLDNSIDTAWLDALIAERVQSE-KPDILLGVMCGSLHIADRQITESFSSFQTSLEKGQIQAANTLTNVVDVELINDGIRYKVQAAKSGANSYFLLMNSSFKEIEVHRLSDGGLLISLEGASYTTYMKEEVDRYRIVIGNQTCVFEKENDPSLLRSPSAGKLINMIVEDGAHVSKGQAYAEIEVMKMVMTLTSQEAGTVTFVRRPGAVLDAGSLLGHLELDDPSLVTKAQPFKGQFLQPENAPVP-EKLNRVHNTYKSILENTLAGYCLPEPFNAQRLRDIIEKFMQSLRDPSLPLLELQEVIASISGRIPISVEKKIRKLMTLYERNITSVLAQFPSQ---------------------QIASVIDSHAATLQKRADRDVFFLTTQSIVQLVQRYRNGIRGRMKAAVHELLRQYYDVESQFQYG--HYDKCVGLVREHNKDDMQTVVNTIFSHSQVAKKNLLVTLLIDH---LWANEPGLTDELANTLSELTSLNRAEHSRVALRSRQVLIAAHQPAYELRHNQMESIFLSAVDMYGHDFHPEN--------LQRLILSETSIFDILHDFFYHSNRAVCNAALEVYVRRAYTSYELTCLQHLELSGGLPLVHFQFLLPTAHPN----------------------RLFSRMSSPD--------GLDQAAAESLGNSFVRTGAIAAFDSFEHFEMYSDEILDLLEDFVSPAMVNAKVLEAVEAADSISDSRHSTSINVSLSDPVTRANAAEEAKSTEPIHIVSVAVRETGELDDLQMAQIFGNYCQEHNEELFQRRIRRITFAALKKR-QFPKFFTFRARDKFTEDRIYRHLEPASAFHLELNRMKTYDLEALPTANQKMHLYLGKAKVSKGQEVTDYRFFIRSIIRHSDLITKEASFEYLQNEGERVLLEAMDELEVAFSHPHAKRTDCNHIFLNFVPTVIMDPAKIEESVTKMIMRYGPRLWKLRVLQAELKMVIRQSPQSPTQAVRLCIANDSGYFLDISMYTEQTEPETGIIKFKAYGEKQGSLHGHPISTPYMTKDFLQQKRFQAQSNGTTYVYDVPDMFRQMTERHWREFSKARPTVDIRTPDKILIECKELVLEGD-NLVEMQRLPGENNCGMVAWRIVLATPEYPNGREIIVIANDLTYLIGSFGIKEDVLFAKASQLARQLKVPRIYISVNSGARIGLAEEVKAMFKIAWEDPEEPDKGFKYLYLSTEDYAQVANL---NSVRAILIEDEGEQRYKITDIIGKDDGLGVENLRYAGLIAGETSQAYEEIVTIAMVTCRTIGIGSYVVRLGQRVIQIDNSHIILTGYAALNKLLGRKVYASNNQLGGTQIMFNNGVTHKTEAIDLDGVYTILDWLSYIPAYIGCDLPIVLPNDRIERPVDFMPT-KSPYDPRWMLGGRVNPVNANDWENGFFDRDSWSEIMASWAKTVVTGRARLGGVPVGVIAVETRTVEVEMPADPANLDSEAKTLQQAGQVWYPDSSYKTAQAIKDFG-REELPLIVFANWRGFSGGMKDMYEQIVKFGAYIVDGLREYKKPVLIYLPPNAELRGGAWAVLDSLINPRYMETYADPEARGGVLEPEGIVEIKYKEKDLVKTIHRLDPTTIALKKELDEANASGDKVRAAQVDEKIKARIAVLMHVYHTVAVHFADLHDTPERMLEKECISEIVPWRDSRRWLYWRLRRLLLEDAYIKKILRAQDNLSVGQAKQMLRRWLVEEKGATEAYLWDKNEEMVSWYEEQIN----AESIVSRNVNSVRRDAIISTISKMLEDCPDVALDAVVGLCQGLTPVNRGVVVRTLAQMQLNEETSNSNQG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00955-1", "uniprot_id": "ACAC_YEAST", "id": "Q00955-1", "name": "Acetyl-CoA carboxylase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MSEES------------------LFESSPQKMEY--------------------------------------EITNYSER-----HTELPGHFIGLNTVDK------------LEESPLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDE---KTGLVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLITHKMTAE-KPDPTLAVICGAATKAFLASEEARHKYIESLQKGQVLSKDLLQTMFPVDFIHEGKRYKFTVAKSGNDRYTLFINGSKCDIILRQLSDGGLLIAIGGKSHTIYWKEEVAATRLSVDSMTTLLEVENDPTQLRTPSPGKLVKFLVENGEHIIKGQPYAEIEVMKMQMPLVSQENGIVQLLKQPGSTIVAGDIMAIMTLDDPSKVKHALPFEGMLPDFGSPVIEGTKPAYKFKSLVSTLENILKGYDN-----QVIMNASLQQLIEVLRNPKLPYSEWKLHISALHSRLPAKLDEQMEELVARSLRRGA----VFPAR---------------------QLSKLIDMAVKNPE-YNPDKLLGAVVEPLADIAHKYSNGLEAHEHSIFVHFLEEYYEVEKLFNGPNVREENIILKLRDENPKDLDKVALTVLSHSKVSAKNNLILAILKHYQPLCKLSSKVSAIFSTPLQHIVELESKATAKVALQAREILIQGALPSVKERTEQIEHILKSSVVKVAYGSSNPKRSEPDLNILKDLIDSNYVVFDVLLQFLTHQDPVVTAAAAQVYIRRAYRAYTIGDIRVHEGVT-VPIVEWKFQLPSAAFS------------------------TFPTVKSKMGMNRAVSVSDLSYVANSQSSPLREGILMAVDHLDDVDEILSQSLEVIPRHQSSSNGPAPDRSGSSAS-------------------------------LSNVANVCVASTEGFESEEE-ILVRLREILDLNKQELINASIRRITFMFGFKDGSYPKYYTFNG-PNYNENETIRHIEPALAFQLELGRLSNFNIKPIFTDNRNIHVYEAVSKTSP----LDKRFFTRGIIRTGHIRDDISIQEYLTSEANRLMSDILDNLEVTDTS----NSDLNHIFINFIAVFDISPEDVEAAFGGFLERFGKRLLRLRVSSAEIRIIIKDPQTGAPVPLRALINNVSGYVIKTEMYTEVKN-AKGEWVFKSLG-KPGSMHLRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLT------DDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGAPAINKMLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGR-ETESG--FEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQEPGQVWHPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPQGMVGIKFRREKLLDTMNRLDDKYRELRSQLSNKSLAPE--VHQQISKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHQVGEAS---RLEKIARIRSWYPASVDH---EDDRQVATWIEENYK-------TLDDKLKGLKLESFAQDLAKKIRSDHDNAIDGLSEVIKMLSTDDKEKLLKTLK--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32874-1", "uniprot_id": "HFA1_YEAST", "id": "P32874-1", "name": "Acetyl-CoA carboxylase, mitochondrial", "aln": "--------------------------------------------------------------------------KGKTITHGQSWGARRIHSHFYIT----------------------IFTITCIRIGQYKLALYLDPYRFYNITGSQ------------------IVRLKGQRPEYRKRIFAHS---------------YRHSSRIGLNFPSRRRYSNYVDRGNIHKHTRLPPQFIGLNTVES------------AQPSILRDFVDLRGGHTVISKILIANNGIAAVKEMRSIRKWAYETFNDEKIIQFVVMATPDDLHANSEYIRMADQYVQVPGGTNNNNYANIDLILDVAEQTDVDAVWAGWGHASENPCLPELLASSQRKILFIGPPGRAMRSLGDKISSTIVAQSAKIPCIPWSGSHIDTIHIDN---KTNFVSVPDDVYVRGCCSSPEDALEKAKLIGFPVMIKASEGGGGKGIRRVDNEDDFIALYRQAVNETPGSPMFVMKVVTDARHLEVQLLADQYGTNITLFGRDCSIQRRHQKIIEEAPVTITKPETFQRMERAAIRLGELVGYVSAGTVEYLYSPKDDKFYFLELNPRLQVEHPTTEMISGVNLPATQLQIAMGIPMHMISDIRKLYGLDPTGTSYIDFKN--------LKRPSPKGHCISCRITSEDPNEGFKPSTGKIHELNFRSSSNVWGYFSVGNNGAIHSFSDSQFGHIFAVGNDRQDAKQNMVLALKDFSIRGEFKTPIEYLIELLETRDFESNNISTGWLDDLILKNLSSDSKLDPTLAIICGAAMKAYVFTEKVRNKYLELLRRGQVPPKDFLKTKFPVDFIFDNNRYLFNVAQSSEEQFILSINKSQCEVNVQKLSSDCLLISVDGKCHTVYWKDDIRGTRLSIDSNTIFLEAELNPTQVISPTPGKLVKYLVRSGDHVFAGQQYAEIEIMKMQMPLVAKSDGVIELLRQPGSIIEAGDVIAKLTLDSPSKANESSLYRGELPVLGPPLIEGSRPNHKLRVLINRLENILNGYHE-----NSGIETTLKELIKILRDGRLPYSEWDSQISTVRNRLPRQLNEGLGNLVKKSVS--------FPAK---------------------ELHKLMKRYLEEN---TNDHVVYVALQPLLKISERYSEGLANHECEIFLKLIKKYYAVEKIFENHDIHEERNLLNLRRKDLTNLKKILCISLSHANVVAKNKLVTAILHEYEPLCQDSSKMSLKFRAVIHDLASLESKWAKEVAVKARSVLLRGIFPPIKKRKEHIKTLLQLHIKDTGAENIHSRNIYSCMRDFGNLIHSNLIQLQDLFFFFGHQDTALSSIASEIYARYAYGNYQLKSIKIHKGAP-DLLMSWQFSSLRNYL-----------------------------VNSDGESDEFTKLSKPPSTS-GKSSANSFGLLVNMRALESLEKTLDEVYEQIH---------IPEERLSSG---------------------------------ENSLIVNILSPIRYRSEND-LIKTLKIKLHENERGLSKLKVNRITFAFIAANAPAVKFYSFDG-TTYDEISQIRNMDPSYEAPLELGKMSNYKIRSLPTYDSSIRIFEGISKFTP----LDKRFFVRKIINSFMYNDQKTTEENLKAEINAQVVYMLEHLGAVDIS----NSDLNHIFLSFNTVLNIPVHRLEEIVSTILKTHETRLFQERITDVEICISVECLETKKPAPLRLLISNKSGYVVKIETYYEKIG-KNGNLILEPCS-EQSHYSQKSLSLPYSVKDWLQPKRYKAQFMGTTYVYDFPGLFHQAAIQQWKRYFPKHKLN------DSFFSWVELIE-QNGNLIKVNREPGLNNIGMVAFEIMVQTPEYPEGRNMIVISNDITYNIGSFGPREDLFFDRVTNYARERGIPRIYLAANSGAKLGIAEELIPLFRVAWNDPSDPTKGFQYLYLAPKDMQLLKDSGKGNSVVVEHKMVYGEERYIIKAIVGFEEGLGVECLQGSGLIAGATSKAYRDIFTITAVTCRSVGIGSYLVRLGQRTIQVEDKPIILTGASAINKVLGTDIYTSNLQIGGTQIMYKNGIAHLTASNDMKAIEKIMTWLSYVPAKRDMSPPLLETMDRWDRDVDFKPAKQVPYEARWLIEGKWDSNNN--FQSGLFDKDSFFETLSGWAKGVIVGRARLGGIPVGVIAVETKTIEEIIPADPANLDSSEFSVKEAGQVWYPNSAFKTAQTINDFNYGEQLPLIILANWRGFSGGQRDMYNEVLKYGSFIVDALVDYKQPILIYIPPFGELRGGSWVVIDPTINPEQMEMYADVESRGGVLEPDGVVSIKYRKEKMIETMIRLDSTYGHLRRTLTEKKLSLE--KQNDLTKRLKIRERQLIPIYNQISIQFADLHDRSTRMLVKGVIRNELEWKKSRRFLYWRLRRRLNEGQVIKRLQKKTCDNKTKMKYDDLLKIVQSWYNDLDV---NDDRAVVEFIERNSK-------KIDKNIEEFEISLLIDELKKKFEDRRGNIV--LEELTRLVDSKRKR---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : : :** ** :*..:*********** :**:*:*:** * ::: ::**.*.**:**.**:***:***:*: ****.*******:::*:*:* : *:************* *** * . : *:**. .** :****::*::***: :* :****: : . :.: ::: :** . ::.* .: :*:*::*************:.: ::* *::*. * ****:*:*::. *******:******. ::*******:*******:****. :: *. **: *: *.: ************:. :. :.************* ***::.*****:****.**:*:: :.*** *:* * . : : *: * . ** :.*****:*::***** *.::******..********. * :*.*:****** *: *::*: : .::*:*:*::****:*:*.:***: ****. * .* * *.*** ** ..: :: : * *.::**: * .: *.:**: . * . . *::* . :* . .*:.. : : :* . :: ::*... **:: * .:* * *::: *: :.. * .:* * :*: : :*:.*** : * .* *: .. ***:*:*** *.* : * : :::** : .* ::. : **.** : : : . . * : : *: :. :. :: **. ** * . :::: .*:* ::: : .:: **:: .: .::. . . :.: .: .:* .* . .::..* ** *: : :. : :* . :: : :**::* ** *: ::.. * .. :: : : .:..*. .**:::*.:*: . *. : * :::: :: : . . : ** *: :: * *: * : .: : ::* * .* * : :: : : ::* . . * : . :: . .: : . : : :: : : . :: * . :.*:** *:::* . : * *:::*: ***.:: .:.: .: . :::: . :: * *** * **. . : * * * : : ::.* .. .:* ****:.* ... : :* . :: . ** : *: ..*: : :. .:* : * *** :. . * * .* :.. . : . : ** .*: ** **::*: ****:**.* :*:* * . .: **: : :* :::* ** * ***.:.: . * ***.**: :*: **:*. ***** ** :: :.:: ** :*:**::.****::*::**: :*::** *. :* ***:****:.:. : . *** **.*: : ::* : .:*** *: :* *** :* **.. .**: ****::***:*:******.**::.. ***** *:**:** .:*:** *:**.***. **::* * *: .: .*: *:*::* *: . * :* ::* *: .*: **:: *: .. :: *:**:.*: * :: **: *:.*******:*:***.***:::* :****** :* :::.****.*:*::****.:.**. *.**::::********* :**:::::*:*::***.* :.:*:::*:** .*****:*.*:*. ** :* *** ::*.****.:* * **::.:.::.:: *:* * * . . . :: :: * *: :* ::::*.*:** . :* * * . : * :* :::***** * * :.: : : . . : : . :.:. :. : *.: . : :: .. . . : .. : : : : : . : ", "identical_positions": 657, "similar_positions": 691, "identity": "25.36%" }, { "cls_id": "homologset.agr.RGD:620501", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D275-1", "uniprot_id": "BATF3_MOUSE", "id": "Q9D275-1", "name": "Basic leucine zipper transcriptional factor ATF-like 3", "aln": "MSQGPPAVS-VLQRSVDAPGNQPQ------SPKDDDRKVRRREKNRVAAQRSRKKQTQKADKLHEEHESLEQENSVLRREISKLKEELRHLSEVLKEHEKMCPLLLCPMNFVQL--RSDPVASCLPR---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97876-1", "uniprot_id": "BATF3_RAT", "id": "P97876-1", "name": "Basic leucine zipper transcriptional factor ATF-like 3", "aln": "MSQGPPAGG-VLQSSVAAPGNQPQ------SPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQL--RPDPVASWSAHDAPDHPSFIWLGTLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NR55-1", "uniprot_id": "BATF3_HUMAN", "id": "Q9NR55-1", "name": "Basic leucine zipper transcriptional factor ATF-like 3", "aln": "MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKADKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDPVAGCLPR---------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** ** . *** ** ******* **:**************************:******:*******::*****.**.***:**:*.****************** : *.****. .: ", "identical_positions": 95, "similar_positions": 16, "identity": "66.9%" }, { "cls_id": "homologset.agr.RGD:620502", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35118-1", "uniprot_id": "GFRA3_MOUSE", "id": "O35118-1", "name": "GDNF family receptor alpha-3", "aln": "MGLSWSPRPPL---LMILLLVLSLWLPLGAGNSLATENRFVNSCTQARKKCEANPACKAAYQHLGSCTSSLSRPLPLEESAMSADCLEAAEQLRNSSLIDCRCHRRMKHQATCLDIYWTVHPARSLGDYELDVSPYEDTVTSKPWKMNLSKLNMLKPDSDLCLKFAMLCTLHDKCDRLRKAYGEACSGIRCQRHLCLAQLRSFFEKAAESHAQGLLLCPCAPEDAGCGERRRNTIAPSCALPSVTPNCLDLRSFCRADPLCRSRLMDFQTHCHPMDILGTCATEQSRCLRAYLGLIGTAMTPNFISKVNTTVALSCTCRGSGNLQDECEQLERSFSQNPCLVEAIAAKMRFHRQLFSQDWADSTFSVVQQQ----------------------------------------------------NSNPALRLQP-RLPILSFS------------------ILPLILLQTLW----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A5Y2-1", "uniprot_id": "A0A8I6A5Y2_RAT", "id": "A0A8I6A5Y2-1", "name": "GDNF family receptor alpha-3", "aln": "MGLSRSPRPPP---LVILLLVLSLWLPLGTGNSLPTENRLVNSCTQARKKCEANPACKAAYQHLDSCTPSLSSPLPSGESATSAACLEAAQQLRNSSLIDCRCHRRMKHQATCLDIYWTVHPVRSLGDYELDVSPYEDTVTSKPWKMNLSKLSMLKPDSDLCLKFAMLCTLNDKCDRLRKAYGEACSGIRCQRHLCLAQLRSFFEKAAESHAQGLLLCPCAPEDAGCGERRRNTIAPSCALPSVAPNCLDLRSFCRADPLCRSRLMDFQTHCHPMDILGTCATEQSRCLRAYLGLIGTAMTPNFISKVNTTVALGCTCRGSGNLQDECEQLEKSFSQNPCLMEAIAAKMRFHRQLFSQDWADSTFSVMQQQQPCSEAPAQATRSVFLHPYLDSAADPLVTGLPQGPLSSPPHPDRLAACDGRENAGLWKKMQPGSLHILSAPDEVLEEARAVTVQNPERPAFKPLLLTPAWAAPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60609-1", "uniprot_id": "GFRA3_HUMAN", "id": "O60609-1", "name": "GDNF family receptor alpha-3", "aln": "MVRPLNPRPLPPVVLMLLLLLPPSPLPLAAGDPLPTESRLMNSCLQARRKCQADPTCSAAYHHLDSCTSSISTPLPSEEPSVPADCLEAAQQLRNSSLIGCMCHRRMKNQVACLDIYWTVHRARSLGNYELDVSPYEDTVTSKPWKMNLSKLNMLKPDSDLCLKFAMLCTLNDKCDRLRKAYGEACSGPHCQRHVCLRQLLTFFEKAAEPHAQGLLLCPCAPNDRGCGERRRNTIAPNCALPPVAPNCLELRRLCFSDPLCRSRLVDFQTHCHPMDILGTCATEQSRCLRAYLGLIGTAMTPNFVSNVNTSVALSCTCRGSGNLQEECEMLEGFFSHNPCLTEAIAAKMRFHSQLFSQDWPHPTFAVMAHQ----------------------------------------------------NENPAVRPQPWVPSLFSCT-------------------LPLILLLSLW----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .*** *::***: . ***.:*:.*.**.*::*** ***:**:*:*:*.***:**.***.*:* *** *.: .* *****:********.* ******:*.:********* .****:************************.******************:**************** :****:** ** :*******.************:* ************.****.*:****:** :* :********:**************************************:*:***:***.**********:*** ** **:**** ********** *******...**:*: :* * . : ** ::* . : :** . * ", "identical_positions": 288, "similar_positions": 67, "identity": "60.63%" }, { "cls_id": "homologset.agr.RGD:620503", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJT2-1", "uniprot_id": "GFRA4_MOUSE", "id": "Q9JJT2-1", "name": "GDNF family receptor alpha-4", "aln": "---------MAHCMESALLLLL--LLGSASFTDGNRCVDAAEACTADERCQQLRSEYVARCLGRAAPGGRPGPGGCVRSRCRRALRRFFARGPPALTHALLFCGCEGSACAERRRQTFAPACAFSGPGLVPPSCLEPLERCERSRLCR-------------------PRLLAFQAS-------CAPAPGSRDRCPEEGG---PRCLRVYAGL-IGTVVTPNYLDNVSARVAPWCGCAASGNRREECEAFRKLFTRNPCLDGAIQAFDSLQPSVLQD-----QTAGCCFPRVSW----------LYALTALALQALL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EPI2-1", "uniprot_id": "GFRA4_RAT", "id": "Q9EPI2-1", "name": "GDNF family receptor alpha-4", "aln": "MLSGAYLRVLNERPGQAVLWSLGCQRGSASSTEGNRCVEAAEACTADEQCQQLRSEYVAQCLGRAG---WRGPGSCVRSRCRRALRRFFARGPPALTHALLFCGCEGPACAERRRQTFAPACAFSGPQLAPPSCLKPLDRCERSRRCR-------------------PRLFAFQAS-------CAPAPGSRDGCPEEGG---PRCLRAYAGL-VGTVVTPNYLDNVSARVAPWCGCEASGNRREECEAFRKLFTRNPCLDGAIQAFDSSQPSVLQDQWNPYQNAGCCFLWVSS----------MSILTALALQALL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9GZZ7-1", "uniprot_id": "GFRA4_HUMAN", "id": "Q9GZZ7-1", "name": "GDNF family receptor alpha-4", "aln": "---------MVRCLGPALLLLL--LLGSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAA------QGGCPRARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRCARAAAGPWRGWGRGLSPAHRPPAAQASPPGLSGLVHPSAQRPRRLPAGPGRPLPARLRGPRGVPAGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAFRGLFTRNRCLDGAIQAFASGWPPVLLDQLNPQGDPEHSLLQVSSTGRALERRSLLSILPVLALPALL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *:* * **** . *****:******** :**:*******:*****. *.* *:************************ * *.**********.*:****** .*****:**: ***** ** * * *** *:. * * * ** *: **.*****:***********.* *******:***** ***** ********* * *.** * . .: ** : *..*** ***", "identical_positions": 165, "similar_positions": 31, "identity": "52.22%" }, { "cls_id": "homologset.agr.RGD:620504", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIK1-1", "uniprot_id": "CDHR5_RAT", "id": "Q9JIK1-1", "name": "Cadherin-related family member 5", "aln": "---------------------------------------------MGAPALLWPPLLLPLLTVLFGHLPGTLAQAQVCSANQTVFTMNENTTVSGPLADIFVPEDQYVTLGQLSTPNAFKVEGN-KLFLIVTPDYE---ENSLLEAVLECKRGDTLVTQFRVFVAVLDINDNAPEFPFTIKEYNVSEDTRVNTIVIPETELKATDADKDDILVYTLQEVTPNASKFFSLVGINSPALKLDQTLDYYKSPNMTFRLLARDTREEN--VIPSHTATATVVLNVLPADLRTPWFLPCS---FTDDYFCIQAQYHTVIPTGHKLPSPLILSPGPIYAVDGDQAINQPIVYSIMMGNTDDTFIINKDDGNLTMAKSIPSPMTFTLVVRAEQ-ADMARYSVTQAVVEARD-VTGNPLQFSQSLYFGTVVLGSEAGTAVKDKTFPSEILRIQAQYLGFP-DLNSAVTYQVTNSSEFIMNKDILLTTVPMETERTIRIEVEANNTVTKDIATTIVEIQVSEREPPSTESPTPPEAGGTTGPSSNTTLETPSTSGTSQGPATTSSGGSAGPFPPAGTTLSPLTSAPTVPGGSPTLGISTSPQTATPGGDATQTPKPGTSQPMVPTPGASTSSQPATPSGSSTQTPKPGTSQPMVPTPGASTSSQPATPSGSSTQTPRPGTSQPMVPTPGASTSSQPATPSG-STQTPKPGTSQPTTT--GPISGVGELGDGQRFSTVDMAVLGGVLGALLLLALIFLIILIHKHYRHRFTCCSGKAKEPQPSGYDNLTFLPDNKAKWSPTSNRKPEPGPEPVQPPLRPPSPMSSSPTPPSSMPPSPQPKASGSPKTVQAGDSPSAVRSILTKERRPEGEGGYKAVWFGKDIGAEADVVVLNEPTADVDSASASGSEGSDDDDDPDQKKSLRLGAVADNTYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHF2-1", "uniprot_id": "CDHR5_MOUSE", "id": "Q8VHF2-1", "name": "Cadherin-related family member 5", "aln": "---------------------------------------------MGAPALLWPSLLLPWLTVLFGQPPGTLAQTQVCSVNQTIFRVEENTTVSEPLVNIFVPDGLHVTLGPLSTPYAFRIEGK-DLFLNVTPDYE---ENSLLQADVECKRGDAVVVRLEVFVAVLDINDNAPKFSFEIKTFNVSEDTKVNTTVIPETQLKATDADINDILVYTLQEVTPNASKFFSLEGVNYPALKLDQTLDYFKNQNMTFMLLARDTWEEN--VEPSHTATATLVLNTLPADLRTPWFLPCS---FTDGYVCIHAQYSAVVPTGHKLPSPLIMSPGPIYAVDGDQAINQSIIYSIIAGNTDGTFIINAHDGNLTMTKSIPSPMKFTLLIRADQ-EDMAQYSVTQAIVEARS-VTGNPLQFSQSLYYGTVVLGSEAGTAVKDKTFPSEILRIQAQYPGFP-DLNSAVTYRVTNSSEFMMNKDIMLTAVPMEEARTIRVEVEASNTVTKDTATAVVEIQVSERE----RTPTPPEAGGTTGPSSNTTMEAPLTSGTSQRPATTSSGGSVGPFPPGGTTLRPPTPASSIPGGSPTLGTSTSPQTTTPGGDSAQTPKPGTSHPTAPTSRTSTSLMTTSSRSDSTQTPKPGTSQPMVPIPGASTSSQPATPSGSSPQTPKPGTSQSTATGP----------------------ISLPST-------GAGEQGDGQRFSTVDMAVLGGVLGALLLLALICLVILVHKHYRHRLACCSGKASEPQPSGYDNLTFLPDHKAKWSPTPNRKPEPSPKLAQPPLRPPSPMSSSPTPPSSTPPSPQPKASGSPKTVQAGDSPSAVRSILTKERRPEGEGGYKAVWFGKDIGAEADVVVLNEPTADVDSASASGSEGSDDDD-PDQKKTLRFGVDADNTYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBB8-1", "uniprot_id": "CDHR5_HUMAN", "id": "Q9HBB8-1", "name": "Cadherin-related family member 5", "aln": "---------------------------------------------MGSWALLWPPLLF---TGLLVRPPGTMAQAQYCSVNKDIFEVEENTNVTEPLVDIHVPEGQEVTLGALSTPFAFRIQGN-QLFLNVTPDYE---EKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGEN--VEPSHTATATLVLNVVPADLRPPWFLPCT---FSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMTFLLLVKGQQ-ADLARYSVTQVTVEAVA-AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFS-DLNSAITYRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPT--SSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCCGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKP--------AEAPMPAEPAPPGPASPGGAPEP---PAAARAGGSPTAVRSILTKERRPEG--GYKAVWFGEDIGTEADVVVLNAPTLDVDGASDSGS--GDEGEGAGRGGGPYDAPGGDDSYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q2D0-1", "uniprot_id": "A0A8M1Q2D0_DANRE", "id": "A0A8M1Q2D0-1", "name": "", "aln": "MKSQTLRLELTPTQRAAQSMLYVKKYQLVTRSHSPPWLFVCIRIWEMDMTFSHKTIIIIFGCLFASFLPKICSTDKICTIPSEPVTIKENNTADIVVVHINTTTKDVTLNLTENPGNAFQLRGS-ELIAKKGLDFETLLGHEELTVQVRCNKTGYRSITLTVIVHVANINDNPPSFGQREYTLDINELTPVNTSIA---LFEATD-DDSEVLYYSLEPTVNRY---FRLKTMYTPNILVNKVLDYDVIQQVKLILYVQDTPLQSQPGERSFTATTTITVNIKDIDNRPPWFQPCTKVTVGSAKICLSLGYRGRVNLTEKQDGALQLQPGPVYARDGDRSRNEEISYKIVRGNEDNIFQIDENSGNISMLKPPDIAGPISLLVLAFQLLNRDQFATTSVTIDVMK-KSRNPPRFEKERYEGYVYSNSGPENMVLRDKMSNRPFRVRARDEDFASGINPDIKYEVQYSSYVNITTDGFILLKKAVRTDAFALQLRAVDVSTGESGTAALSVNVLP------PVG-IQSQDES----------------------------------------------------------YRAGDMALLGFVMAALLVLCLIVIGYLISRVKKGNSDAFKLSECLGPCLKFTQPPNRPRDSMQFTNDGFLNEGDTGRSRS----------------------------------------------------------------RRADLREQRLDAVQGARVRVIPRERQRHCSSCGFQVHANHSHYSPGLPVKEK------------------------PSKQR-VKSILAKERRKDD-KKTVWFKESED-SSDIEVEIIPDTIGLKPEDDEDKVEGDFASNPPEDGGMVLGELTMLSIKDSRSRETDITDSKDGLNTDRRDQ----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YYJ8-1", "uniprot_id": "A0A8M6YYJ8_DANRE", "id": "A0A8M6YYJ8-1", "name": "", "aln": "----------------------------------------------MDLRPKGAAVFIFLLVIFT--FSKCSEAQDLCSVPLPFIFIKENNTIDALVTTINAAEGVTAVITGQNPPDLFDINDEYQLIAKTVMDYEKFDKDNPYLVNIECTKPGSTSTSLLLRIVLEDINDNPPSFKESWYSLEVKELTKVDTSVG---LITATDPDESDRLYYRLE-SPEGE---FDVETSFNPNILVKKLLDYDKVKQVTMTLYAQDTQIGS-SAEVSHTATATVVVNIIDIDNRPPWFQPCTEYIFETSTVCINSGYNGVVTLKEQETDPLKLMPGPVYGIDGDAGIKELIGYTFMGGNEDGIFNINTDTGNITMLKPVDVVGPFVLTVMAFQKLNPDQFATTTVILKVALTASEFPPKFTKESYEGFISEDAGVDSLVLEGKTSNRALRVQATDEDFSNGYNPNLRFEIVDGTDFYITPEGFILMAKAVTPGTVNLEMRVIDTENDESSTASLVVEITPGVPTTTPVTTITTTDNTDSTQLTDITDTSHPSTHTTTHPGTYTTAHP-----------------NTGGQLGKAGDFTSGDMAAVGATLAVFVVICLVCIGLLAHRIKGHNAAWKKLSEASIFRSTLGGGSGGPKEGMQYINESFQNDGDTPDNSR----------------------------------------------------------------FAADL-ENKLEPEQSG------TSQEKITRSAFLQTNSKPPADSSSLADSEN------------------------TDGEKEVKPILTKERRTDEGYKSVWFREDIDPDTKEEVVIIPDTG--EADGDHEDDEDDDSEEDDED--------------DLRT-DMDLEDD-DRLTSM--------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::: : . . *: . ::**.. :. * .. . .. * :... .*: *:* .. . : * . : : : : ::***.*.* :.* * *:: : : * * * .: * * *: * : * : :.: **: ::.: * .:** . *.***:*:.:* * *.*** **: . .*: * : . ..* : ***:*. *** . :: * *.:. ** :. * *. . **::: :. : * : . * : :::.* . :.. : * :* : * * : .: * ... :*::* *. . *. : :.: : . : : .: :. ::.. :. . .*: : ::: . : : : : * : . . . * . . : *.: . . * * . : .. ..: . :: . .. . . :. . . . * ..:. ..: : . *. : ", "identical_positions": 81, "similar_positions": 193, "identity": "8.79%" }, { "cls_id": "homologset.agr.RGD:620505", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CIT0-1", "uniprot_id": "CRH_MOUSE", "id": "Q8CIT0-1", "name": "Corticotropin-releasing hormone", "aln": "MRLRLLVSAGMLLVALSSCLPCRALLSRGSVP---RAPRAPQPLNFLQP----EQPQQPQ--PVLIRMGEEYFLRLGNLNRSPAARLSPNSTPLTAGRGSRPSHDQAAANFFRVLLQQLQMPQRSLDSRAEPAERGAEDALGGHQGALERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01143-1", "uniprot_id": "CRH_RAT", "id": "P01143-1", "name": "Corticotropin-releasing hormone", "aln": "MRLRLLVSAGMLLVALSPCLPCRALLSRGSVS---GAPRAPQPLNFLQP----EQPQQPQ--PILIRMGEEYFLRLGNLNRSPAARLSPNSTPLTAGRGSRPSHDQAAANFFRVLLQQLQMPQRPLDSSTELAERGAEDALGGHQGALERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06850-1", "uniprot_id": "CRH_HUMAN", "id": "P06850-1", "name": "Corticotropin-releasing hormone", "aln": "MRLPLLVSAGVLLVALLPCPPCRALLSRGPVPGARQAPQHPQPLDFFQPPPQSEQPQQPQARPVLLRMGEEYFLRLGNLNKSPAAPLSPASSLLAGGSGSRPSPEQATANFFRVLLQQLLLPRRSLDSPAALAERGARNALGGHQEAPERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ******:***** .* *********.*. **: ****:*:** ******* *:*:**************:**** *** *: *:.* ***** :**:*********** :*:*.*** : *****.:****** * ************************************************", "identical_positions": 150, "similar_positions": 21, "identity": "76.53%" }, { "cls_id": "homologset.agr.RGD:620506", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERL7-1", "uniprot_id": "GMFG_MOUSE", "id": "Q9ERL7-1", "name": "Glia maturation factor gamma", "aln": "MSDSLVVCEVDPELKETLRKFRFRKETNN--AAIIMKVD-KDRQMVVLEDELQN-----ISPEELKLELPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCK-PEQQMMYAGSKNRLVQTAELTKVFEIRT--TDDLTETWLKEKLAFFR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80T18-1", "uniprot_id": "GMFG_RAT", "id": "Q80T18-1", "name": "Glia maturation factor gamma", "aln": "MSDSLVVCDVDPELKETLRKFRFRKETNN--AAIIMKVD-KDRQMVVLEDEFQN-----VSPEELKLELPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCK-PEQQMMYAGSKNRLVQIAELTKVFEIRT--TDDLNETWLKEKLAFFR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60234-1", "uniprot_id": "GMFG_HUMAN", "id": "O60234-1", "name": "Glia maturation factor gamma", "aln": "MSDSLVVCEVDPELTEKLRKFRFRKETDN--AAIIMKVD-KDRQMVVLEEEFQN-----ISPEELKMELPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCK-PEQQMMYAGSKNRLVQTAELTKVFEIRT--TDDLTEAWLQEKLSFFR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJL6-1", "uniprot_id": "GMF_DROME", "id": "Q9VJL6-1", "name": "Glia maturation factor", "aln": "MSDNQ-ICDISNEVLEELKKFRFSKSKNN--AALILKVD-REKQTVVLDEFIDD-----ISVDELQDTLPGHQPRYVIYTYKMVHDDQRISYPMCFIFYTPRDSQ-IELQMMYACTKSALQREVDLTRVYEIRE--LDELTEEWLKAKLK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12156-1", "uniprot_id": "AIM7_YEAST", "id": "Q12156-1", "name": "Protein AIM7", "aln": "---MSNLYKIGTETRNKIKKFRTSTARTDSIKALSIKIEPKPSYEIIVDEDEQEELDEIEDLSELAEILPDNSPRFVLTAYPTTTKDGFKQTPLVLVYWKPMTVVSQEWKMLYAGALEMIREECGTFKLIEVSSGLEDDSDVEELREQLENC-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:. * : ::*** . : *: :*:: : ::::: :: . .** ** ..**:*: :* . .* . *: ::: .* * :*:** : . : . :: *: *: *: :* ", "identical_positions": 25, "similar_positions": 48, "identity": "16.34%" }, { "cls_id": "homologset.agr.RGD:620507", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63155-1", "uniprot_id": "CRNL1_RAT", "id": "P63155-1", "name": "Crooked neck-like protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVERARTIYERFVLVHPAVKNWIKYARFEEKHAYFAHARKVYERAVEFFG--------DEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQEAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEADTVREVYERAIANVPP--IQEKRHWKRYIYLWVNYALYEELEAKDPERTRQVYQASL-ELIPHKKFTFAKMWLYYAQFEIRQKNLPFARRALGTSIGKCPKNKLFKGYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIERARAIYELAISQPR----LDMPEVLWKSYIDFEIEQEETERTRNLYRQLLQRTQH-VKVWISFAQFELSSGKEGS------------------------VAKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEDEFGTVSDKERVDKLMPEKVKKRRKVQADDGSDAGWEEYYDYIFPEDAAN-QPN-LKLLAMAKLWKKQQQEREA---------------------------------------AEQDPDKDIDESESSSF-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63154-1", "uniprot_id": "CRNL1_MOUSE", "id": "P63154-1", "name": "Crooked neck-like protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVERARTIYERFVLVHPAVKNWIKYARFEEKHAYFAHARKVYERAVEFFG--------DEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQEAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEADTVREVYERAIANVPP--IQEKRHWKRYIYLWVNYALYEELEAKDPERTRQVYQASL-ELIPHKKFTFAKMWLYYAQFEIRQKNLPFARRALGTSIGKCPKNKLFKGYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIERARAIYELAISQPR----LDMPEVLWKSYIDFEIEQEETERTRNLYRQLLQRTQH-VKVWISFAQFELSSGKEGS------------------------VAKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEDEFGTVSDKERVDKLMPEKVKKRRKVQADDGSDAGWEEYYDYIFPEDAAN-QPN-LKLLAMAKLWKKQQQEREA---------------------------------------AEQDPDKDIDESESSSF-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZJ0-1", "uniprot_id": "CRNL1_HUMAN", "id": "Q9BZJ0-1", "name": "Crooked neck-like protein 1", "aln": "MTATVENLTFQKDTLGNAVDKNTSRLELRSYSLAGRHGSTEPLVLAWSSQFRRLTWGCALDALHRSPCVAASQHGVTHLIRSSRTPHSTRCRKEDAQPGHHGNGAASVTAQARGQRSVLQVPLPVPRSCLFSESFVVSVSSQSRFLASVPGTGVQRSTAADMAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFG--------DEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPP--IQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASL-ELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELAISQPR----LDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQH-VKVWISFAQFELSSGKEGS------------------------LTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPEKVKKRRKVQTDDGSDAGWEEYFDYIFPEDAAN-QPN-LKLLAMAKLWKKQQQEKED---------------------------------------AEHHPDEDVDESES----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803R7-1", "uniprot_id": "CRNL1_DANRE", "id": "Q803R7-1", "name": "Crooked neck-like protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------MASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPKQKITDKEELNDYKLKKRKGFEDNIRKNRTVISNWIKYAQWEESLQEVQRSRSIYERALDVDHRNITLWLKYAEMEMKNRQVNHARNIWDRAITILPRVNQFWYKYTYMEEMLGNIAGCRQVFERWMEWEPEEQAWHSYINFELRYKEVDKARSIYENFVMVHPEVKNWIKYAHFEEKHGYVARGRKVFERAVEFFG--------EEQVSENLYVAFARFEEKQKEFERVRVIYKYALDRIPKQQAQELFKNYTVFEKRFGDRRGIEDVIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDADADTVREVYERAIANIPP--IQEKRHWRRYIYLWINYALYEELEVKDPERTRQVYKACL-ELIPHKKFTFAKIWLLYGQFEIRQKNLQNARRGLGTAIGKCPKNKLFKGYIELELQLREFDRCRKLYEKYLEFSPENCTTWIKFAELETILGDTDRSRAIFELAIGQPR----LDMPEVLWKSYIDFEIEQEEYDNTRGLYKRLLQRTQH-VKVWISYAQFELSIDTEDR------------------------VQRCRQVYEEANKGMQNCEEKEERLMLLESWRDYEEEFGSFTHKERVRKLLPEKVKKRRKITAEDGSDAGWEEYYDYIFPEDAAN-QPN-LKLLAMAKMWKKQQQQEEEDDDEEEDENDKEEQQVPEGKDAQESPEAEEQEPAAGGEQAEKEYDDRDDEDESSSSSSSDSESDEDQKDKTEHNKPDTEQQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17886-1", "uniprot_id": "CRN_DROME", "id": "P17886-1", "name": "Protein crooked neck", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------MERPQKMPKVAKVKNKAPAEVQITAEQLLREAKERDLEILPPPPKQKISDPAELADYQQRKRKTFEDNLRKNRMVVSHWIKYAQWEEQQQEIQRARSIWERALDNEHRNVTLWLKYAEMEMKNKQVNHARNLWDRAVTIMPRVNQFWYKYTYMEEMLENVAGARQVFERWMEWQPEEQAWQTYVNFELRYKEIDRAREIYERFVYVHPDVKNWIKFARFEESHGFIHGSRRVFERAVEFFG--------DDYIEERLFIAFARFEEGQKEHDRARIIYKYALDHLPKDRTQELFKAYTKHEKKYGDRAGIEDVIVSKRKYQYEQEVAANPTNYDAWFDYLRLIEAEGDRDQIRETYERAISNVPP--ANEKNFWRRYIYLWINYALYEELEAEDAERTRQIYKTCL-ELIPHKQFTFSKLWLLYAQFEIRCKELQRARKALGLAIGMCPRDKLFRGYIDLEIQLREFERCRMLYEKFLEFGPENCVTWMKFAELENLLGDTDRARAIFELAVQQPR----LDMPELLWKAYIDFEVALGETELARQLYERLLERTQH-VKVWMSFAKFEMGLSHGDSGPDAELN-----------------VQLARRIYERANEMLRQLGDKESRVLLLEAWRDFERDASDSQEMQKVMDKMPRRIKKRQKIVSDNGVEEGWEEVFDYIFPEDEMA-RPN-LKLLAAAKMWKTQKDNTVDD-------------------------------PPATAIASEPEPAADAAPADTTDSGD-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12309-1", "uniprot_id": "CLF1_YEAST", "id": "Q12309-1", "name": "Pre-mRNA-splicing factor CLF1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTLEPTAVDTHVSAEQILRDVYKKGQKARG-STNIDILDLEELREYQRRKRTEYEGYLKRNRLDMGQWIRYAQFEIEQHDMRRARSIFERALLVDSSFIPLWIRYIDAELKVKCINHARNLMNRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWCSLEPGVNAWNSFVDFEIRQKNWNGVREIYSKYVMAHPQMQTWLKWVRFENRHGNTEFTRSVYSLAIDTVANLQNLQIWSDMEVAKLVNSFAHWEAAQQEYERSSALYQIAIEKWPSN--QLLKAGLLDFEKQFGDINSIEETISYKRKMEYETILSNNAYDYDTWWLYLDLIS-ESFPKQIMQTFEKAIVDSRPKELSKNVQWKRYIYLWMRYICYVELELENSLLEEELFQRLIDDIIPHKHFTFSKIWLMYAKFLIRHDDVPKARKILGKAIGLCPKAKTFKGYIELEVKLKEFDRVRKIYEKFIEFQPSDLQIWSQYGELEENLGDWDRVRGIYTIALDENSDFLTKEAKIVLLQKYITFETESQEFEKARKLYRRYLELNQYSPQSWIEFAMYQTSTPTEQQLLDLAKLQSENVDEDIEFEITDENKLEARKVFEEAIVFFKEKDDKQGRLSILEALKDYEETYGTELDQETVKKRFPKVIKKVR---LQNGVEE---EFVDYIFPDDIDDDKPKPSKFLELAKKWKQEQAL------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : :..:.:::***:**:. :: : ..: .* * ** :*: :**. :*. :::** :.:**:***:* . ::::*:***:**** : :.**::* : *:* : :*****: :**:: :***:::**** :** * *: *.:: :* . :* :**:::::**:* *: : .* **..:* .** ::.*:*:.:**: *. * *:. *:: .. .: .* :**::* *:*.:* :*: *::: ..: * * .**::** .**: * **: :** : *. :**:*: ** *:. :. . : :.:*:** : * .:: *:******:.* * *** ::. .:::: : ::****:***:*:*: *.:* ** .:: **: ** :** **: * *: **:**::*:**:* * :***::** *.: * ::.*** *** :* *.*: :*: : : :* : ** ** * : :* **.: *: .*: : *:.:* :: . .*:::*.* ::: :*: *: :**: :.:* . . : * . :*. :** : ::* : * *****:* :*: *:* ** ** :: ", "identical_positions": 209, "similar_positions": 235, "identity": "21.84%" }, { "cls_id": "homologset.agr.RGD:62051", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51433-1", "uniprot_id": "PA2G5_RAT", "id": "P51433-1", "name": "Phospholipase A2 group V", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRLLTLAWFLACSVPAVPG--------------------------GLLELKSMIEKVTGKNAVKNYGFYGCYCGWGGHGTPKDGTDWCCRMHDRCYGLLEEKHCAIRTQSYDYRFTQDLVICEHDS-------FCPVRLCACDRKLVYCLRRNLWSYN------RLYQYYPNFLC--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97391-1", "uniprot_id": "PA2G5_MOUSE", "id": "P97391-1", "name": "Phospholipase A2 group V", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGLLTLAWFLACSVPAVPG--------------------------GLLELKSMIEKVTGKNAFKNYGFYGCYCGWGGRGTPKDGTDWCCQMHDRCYGQLEEKDCAIRTQSYDYRYTNGLVICEHDS-------FCPMRLCACDRKLVYCLRRNLWTYN------PLYQYYPNFLC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39877-1", "uniprot_id": "PA2G5_HUMAN", "id": "P39877-1", "name": "Phospholipase A2 group V", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGLLPLAWFLACSVPAVQG--------------------------GLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGTDWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGP-------FCHVNLCACDRKLVYCLKRNLRSYN------PQYQYFPNILCS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IML0-1", "uniprot_id": "Q8IML0_DROME", "id": "Q8IML0-1", "name": "Phospholipase A2", "aln": "MLWIMGLVVAAVRLNGQASGAANVTVIEDIRSAFRGVTNDTELLNHIIPEMYGASMRSANPSFVFKMPSKSNGGGDDFELLTMQRSDFAEPIFPNISQSATAIDSPSTIPPETSVKTSLMVSPQQDWQQMGLDGWTGELKPPVASLEQDHRDTRPPISWQNSYPHDEIRLEFQNHHFDGRVTDIRVITQTTSKPAEMEDLMNVQNVYIARVNDPFGYSMKWSFTNDSSREKELLPEGDRGKRDVARLYSMIKCSTGCDPLIYKG-YGCYCGFGGHGVPADGIDRCCRVHDKCYGQSNCISYLEYFVPYVWKCYRGKPLCAVDHGEFGGPDSCAARLCQCDLRLSRCLKRYYCPHRRSICHSSRSRRLQNLIFFD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *: : . . * * .: * ***: ** :.. * ******:**:*.* ** * ** **:*** : .* :: . * . * .** ** :* **:* .:. : *:: ", "identical_positions": 43, "similar_positions": 30, "identity": "11.5%" }, { "cls_id": "homologset.agr.RGD:620510", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60520-1", "uniprot_id": "GBRL2_HUMAN", "id": "P60520-1", "name": "Gamma-aminobutyric acid receptor-associated protein-like 2", "aln": "MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60521-1", "uniprot_id": "GBRL2_MOUSE", "id": "P60521-1", "name": "Gamma-aminobutyric acid receptor-associated protein-like 2", "aln": "MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P60522-1", "uniprot_id": "GBRL2_RAT", "id": "P60522-1", "name": "Gamma-aminobutyric acid receptor-associated protein-like 2", "aln": "MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38182-1", "uniprot_id": "ATG8_YEAST", "id": "P38182-1", "name": "Autophagy-related protein 8", "aln": "MKSTFKSEYPFEKRKAESERIADRFKNRIPVICEKAEKSDIPEIDKRKYLVPADLTVGQFVYVIRKRIMLPPEKAIFIFVNDTLPPTAALMSAIYQEHKDKDGFLYVTYSGENTFGR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **.::.:*:* .** :* :: :*:*** **.. *:* :*********:*:**.**:::***** **.*****:**:.*:* :: *. :*::.**:******:******** ", "identical_positions": 65, "similar_positions": 36, "identity": "55.56%" }, { "cls_id": "homologset.agr.RGD:620511", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43186-1", "uniprot_id": "CRX_HUMAN", "id": "O43186-1", "name": "Cone-rod homeobox protein", "aln": "--------------MMAYMNPGPHYSVNALALSG---------PSVDLMHQAVPYPS-----APRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPG-----------------------------------PSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYA---------------PASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLG--------------------------------------------------------------------------------------------GPALSPLSG--------PSVGPSLAQSPTSLSGQSYGA----YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54751-1", "uniprot_id": "CRX_MOUSE", "id": "O54751-1", "name": "Cone-rod homeobox protein", "aln": "--------------MMAYMNPGPHYSVNALALSG---------PNVDLMHQAVPYSS-----APRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGAQTKARPAKRKAGTSPRPSTDVCTDPLGISDSYSPSLPG-----------------------------------PSGSPTTAVATVSIWSPASEAPLPEAQRAGLVASGPSLTSAPYAMTYA---------------PASAFCSSPSAYASPSSYFSGLD--PYLSPMVPQLG--------------------------------------------------------------------------------------------GPALSPLSG--------PSVGPSLAQSPTSLSGQSYST----YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WTQ9-1", "uniprot_id": "Q9WTQ9_RAT", "id": "Q9WTQ9-1", "name": "Cone-rod homeobox protein", "aln": "--------------MMTYMNPGPHYSVNALALSG---------PSVDLMHQAVPYSS-----APRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGVQAKARPAKRKAGTSPRPSTDVCTDPLGISDSYSPSLPG-----------------------------------PSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGSSLTSAPYAMTYA---------------PASAFCSSPSAYASPSSYFSGLD--PYLSPMVPQLG--------------------------------------------------------------------------------------------GPALSPLSG--------PSVGPSLAQSPTSLSGQSYST----YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JIZ3-1", "uniprot_id": "Q8JIZ3_DANRE", "id": "Q8JIZ3-1", "name": "", "aln": "--------------MMSYIKQ-PHYAVNGLTLSA---------SGMDLLHTAVGYPA-----TPRKQRRERTTFTRTQLDILEALFTKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ------QQQTSG-QPKPRPPKKKS--SPPP--DLTSDPGTSSSVVAAPTPT-----------------------------------VPPSVSAGTAPVSVWSPTSLSPLPDPLCG--SGTPCVQRPAPYPMSYG---------------QPSSYSQG---YGS-SPYFSGLDCSPYLSPMTTQLSAS------------------------------------------------------------------------------------------GGALSPLTV--------PSMGGSLSQSP-SLSSQGYSTASLGFSSVDCLDYKDQQ-AWKLNFSTVDCLDHK------FQVL-----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22810-1", "uniprot_id": "HMOC_DROME", "id": "P22810-1", "name": "Homeotic protein ocelliless", "aln": "MAAGFLKSGDLGPHPHSYGGPHPHHSVPHGPLPPGMPMPSLGPFGLPHGLEAVGFSQGMWGVNTRKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSSSANSRSNSNNNGSSSNNNTQSSGGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHSSFLSAAAAAASGGTNQSANNNSNNNNQGNSTPNSSSSGGGGGSQAGGHLSAAAAAAALNVTAAHQNSSPLLPTPATSVSPVSIVCKKEHLSGGYGSSVGGGGGGGGASSGGLNLGVGVGVGVGVGVGVSQDLLRSPYDQLKDAGGDIGAGVHHHHSIYGSAAGSNPRLLQPGGNITPMDSSSSITTPSPPITPMSPQSAAAAAHAAQSAQSAHHSAAHSAAYMSNHDSYNFWHNQYQQYPNNYAQAPSYYSQMEYFSNQNQVNYNMGHSGYTASNFGLSPSPSFTGTVSAQAFSQNSLDYMSPQDKYANMV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* **::* .*. .: ** :. .************:**: ***** **:***:: ***************************** .:. .. : . . :: *. . .: *. . . . * ::..*... .. : *. . . .: . . . .... .. .: . : : * *.. ...:. * ::*: *.: .**. : : . .: .*.... : . :::: .. : : : ", "identical_positions": 73, "similar_positions": 97, "identity": "13.47%" }, { "cls_id": "homologset.agr.RGD:620512", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64428-1", "uniprot_id": "ECHA_RAT", "id": "Q64428-1", "name": "Trifunctional enzyme subunit alpha, mitochondrial", "aln": "MVASRAIGSLSRFSAFRILR---------SRGCICHS--FTTSSALLSRTHINYGVKGDVAVIRINSPNSKVNTLNKEVQSEFVEVMNEIWANDQIRSAVLISSKPGCFVAGADINMLASCTTPQEAARISQEGQKMFEKLEKSPKPVVAAISGSCLGGGLELAIACQYRIATKDRKTVLGVPEVLLGILPGAGGTQRLPKMVGVPAAFDMMLTGRNIRADRAKKMGLVDQLVDPLGPGIKSPEERTIEYLEEVAVNFAKGLADRKVSAKQSK-GLMEKLTSYAMTIPFVRQQVYKTVEEKVKKQTKGLYPAPLKIIDAVKTGLEQGNDAGYLAESEKFGELALTKESKALMGLYNGQVLCKKNKFGAPQKTVQQLAILGAGLMGAGIAQVSVDKGLKTLLKDTTVTGLGRGQQQVFKGLNDKVKKKALTSFERDSIFSNLIGQLDYKGFEKADMVIEAVFEDLAVKHKVLKEVESVTPEHCIFASNTSALPINQIAAVSQRPEKVIGMHYFSPVDKMQLLEIITTDKTSKDTTASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDALTTGFGFPVGAATLADEVGIDVAQHVAEDLGKAFGERFGGGSVELLKLMVSKGFLGRKSGKGFYIYQSGSK-NKNLNSEIDNILVNLRLPAKPEVSSDEDIQYRVITRFVNEAVLCLQEGILATPEEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKVVDRLRKYESAYGTQFTPCQLLRDLANNSSKKFYQ-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMS1-1", "uniprot_id": "ECHA_MOUSE", "id": "Q8BMS1-1", "name": "Trifunctional enzyme subunit alpha, mitochondrial", "aln": "MVASRAIGSLSRFSAFRILR---------SRGCICRS--FTTSSALLTRTHINYGVKGDVAVIRINSPNSKVNTLNKEVQSEFIEVMNEIWANDQIRSAVLISSKPGCFVAGADINMLSSCTTPQEATRISQEGQRMFEKLEKSPKPVVAAISGSCLGGGLELAIACQYRIATKDRKTVLGVPEVLLGILPGAGGTQRLPKMVGVPAAFDMMLTGRNIRADRAKKMGLVDQLVEPLGPGIKSPEERTIEYLEEVAVNFAKGLADRKVSAKQSK-GLVEKLTTYAMTVPFVRQQVYKTVEEKVKKQTKGLYPAPLKIIDAVKAGLEQGSDAGYLAESQKFGELALTKESKALMGLYNGQVLCKKNKFGAPQKNVQQLAILGAGLMGAGIAQVSVDKGLKTLLKDTTVTGLGRGQQQVFKGLNDKVKKKALTSFERDSIFSNLIGQLDYKGFEKADMVIEAVFEDLGVKHKVLKEVESVTPEHCIFASNTSALPINQIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTDKTSKDTTASAVAVGLRQGKVIIVVKDGPGFYTTRCLAPMMSEVMRILQEGVDPKKLDALTTGFGFPVGAATLADEVGVDVAQHVAEDLGKAFGERFGGGSVELLKQMVSKGFLGRKSGKGFYIYQEGSK-NKSLNSEMDNILANLRLPAKPEVSSDEDVQYRVITRFVNEAVLCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKVVDRLRKYESAYGTQFTPCQLLLDHANNSSKKFYQ-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40939-1", "uniprot_id": "ECHA_HUMAN", "id": "P40939-1", "name": "Trifunctional enzyme subunit alpha, mitochondrial", "aln": "MVACRAIGILSRFSAFRILR---------SRGYICRN--FTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDK-GLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVK-RKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFYQ-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V397-1", "uniprot_id": "Q9V397_DROME", "id": "Q9V397-1", "name": "Trifunctional enzyme subunit alpha, mitochondrial", "aln": "MSATRFLSAVGQISRQQLLQNKCTRALPISAQLLQRRRLMSTNPAPVANKHLHTKVVNGVLVIKIDSPNAKVNSLGSEVSDEFERVIKDLETNPAVNSAVLISGKPGCFVAGADIGMLEACQTAEEATLISHGAQVMFDRMERSKKPIVAAISGVCLGGGLELALACHYRIATKDSKTKLGLPEVMLGLLPGGGGTVRLPKLTSVPTALDMELTGKQVRADRAKRLGIVDLLVDPLGPGLQPAEQNTIEYLEKTAVQVANDLASGKLRVNREKSGLVSKIQSFVMDTDFVKNKIFDTARKQVLKASNGLYPAPLKILDVIRAGVDKGTDAGYEAERKGFGELSATPESKGLIALFRGQTECKKNRFGKPERPVKTVGVLGAGLMGAGIVQVSVDKGYQVVMKDATEAGLARGIGQVQKGLETAVKRKRISALERDQTLASLRPTLDYSDFKNADIIIEAVFEDIKVKHRVIKELEAVVPEHCVIATNTSAIPITKIAAGSSRPEKVVGMHYFSPVDKMQLLEIITHPGTSKDTIAQAVAVGLKQGKVVITVGDGPGFYTTRILSTMLSEAIRLLQEGVDPKDLDQYTKKFGFPVGAATLADEVGIDVGSHIAVDLAKAFGERFSGGNLEVMNDLVLAGFLGRKSGKGIFLYDGQKRGTRPVNNDALEIVKQKYALVSKGANAPEDLTLRMVSRFINEAVLCLEEKILDSPLEGDVGAVFGLGFPPFSGGPFRWVDQYGAGKLVSKMQSYAELYGAPFKPAQTLLDMAKDPSKKFYPKTGSSKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * * :. :.::* ::*: * : : :: ..* ::..*:: * ..* *::*:***:***:*..*: .** .*:::: :. :.******.*****:*****.** :* * :*.: :*: .* :.:::*:* **:****.* *******:*::*:******* ** ** ***:** ***.*** ****:..**:*:** ***:.:******::*:** **:*****::..*:.******:.*: .*:.**. *: ::.* **:.*: ::.* **:::::....::* * ::*********:*.:::*:::*.**** .* : **** * ***.*:.*:.**. ****:** *:: *: :.:**********.******* :.::**:* :.* ** ** ***: **:* ::::***. ::.* ***..*::**::*******: :**:*:**:*:* *:**::*:****:**.:*** *.*****:****************** ***** *.******:****:*.* ********* *:.*:**.:*:********.** *. **********.****:**..*:* **.*.*****.**. *::. :* **********:::*: : : :*.: .*: . . ..: **: *:::**:****:**:* ** :* ***:********** *****:** *** *:*.:::.* ** *.*.* * * *:...**** ", "identical_positions": 403, "similar_positions": 239, "identity": "51.47%" }, { "cls_id": "homologset.agr.RGD:620513", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60587-1", "uniprot_id": "ECHB_RAT", "id": "Q60587-1", "name": "Trifunctional enzyme subunit beta, mitochondrial", "aln": "MTTILTSTFRNLSTTSKWALRFSVRPLSCSSQVQSAPAVQTKSKKTLAKPNLKNIVVVEGVRIPFLLSGTSYKDLMPHDLARAALSGLLYRTNIPKDVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISSNQAMTTAVGLIASGQCDVVVAGGVELMSDVPIRHSRNMRKMMLDLNKAKTLAQRLSLLTKFRLNFLSPELPAVAEFSTNETMGHSADRLAAAFAVSRMEQDKYALRSHSLAKKAQDEGHLSDIVPFKVPGKDTVS-KDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMSEDRALAMGYKPKAYLRDFIYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAQNYMGRKTKVGAPPLEKFNIWGGSLSLGHPFGATGCRLVMAAANRLRKDGGQYALVAACAAGGQGHAMIVEAYPK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JY0-1", "uniprot_id": "ECHB_MOUSE", "id": "Q99JY0-1", "name": "Trifunctional enzyme subunit beta, mitochondrial", "aln": "MTTILTSTFRNLSTTSKWALRSSIRPLSCSSQLHSAPAVQTKSKKTLAKPNMKNIVVVEGVRIPFLLSGTSYKDLMPHDLARAALSGLLHRTNIPKDVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISSNQAMTTAVGLIASGQCDVVVAGGVELMSDVPIRHSRNMRKMMLDLNKAKTLGQRLSLLSKFRLNFLSPELPAVAEFSTNETMGHSADRLAAAFAVSRMEQDEYALRSHSLAKKAQDEGHLSDIVPFKVPGKDTVT-KDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMSEDRALAMGYKPKAYLRDFIYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAQNYMGRKTKVGSPPLEKFNIWGGSLSLGHPFGATGCRLVMAAANRLRKDGGQYALVAACAAGGQGHAMIVEAYPK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55084-1", "uniprot_id": "ECHB_HUMAN", "id": "P55084-1", "name": "Trifunctional enzyme subunit beta, mitochondrial", "aln": "-MTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVT-KDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1H8-1", "uniprot_id": "Q9W1H8_DROME", "id": "Q9W1H8-1", "name": "acetyl-CoA C-acyltransferase", "aln": "--MSLQNVCR---KGNAFNLLNVARKVQCRALSAAVANPQPKQK------NSQNIVLVDGVRTPFLTSGTTYSKLMPHELARHSLLSLLQKNRLDKELIDYIVYGSVIQEVKTSNIAREAALAAGFSNKTPAHTVTMACISSNAAITTGMGLIATNTYDVIVAGGVEFMSDVPIRHSRKMRSLLLKANKAKTLGQRLALLSTFRPDFLAPELPAVAEFSSGETMGHSADRLASAFNVSRSEQDEYALRSHTLAKEAQEKGYFTDLVPFKVSGVDQIVDKDNGIRVSSPESLAKLRPAFVKPYGTVTAANASFLTDGASACIIMTEEKAKQLGLKPKAYLRDFLFVSQDPVNQLLLGPAYGIPKLLKKAGLTLKDIDSWEIHEAFAGQIVANLKALDSDWFCKTYLGLNEKVGTPDLSKWNNWGGSLSIGHPFAATGVRLCMHTANRLVREDGKLGVVAACAAGGQGVAMLIERYPGATAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . . : * * :.* : :.. *.* * * :*:*:*:*** *** ***:*..****:*** :* .** :. : *:::***::*:*********:******.****:*************:* *:**.:****:. **:******:**********:**.::*. ****::.***:*::.** :**:******:***:.***********:** *** ***:******:***:**::* ::*:*****.* * : ****** ** *.:***:***:**********:********* :**:*::* :* *********::***** :******:*. **:*:*****::***::*:****:***:**:**:*****.:.*:* : *** * *.*:* ******:****.*** ** * :**** ::.*: .:********** **::* ** ", "identical_positions": 290, "similar_positions": 113, "identity": "60.42%" }, { "cls_id": "homologset.agr.RGD:620514", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15651-1", "uniprot_id": "ACADS_RAT", "id": "P15651-1", "name": "Short-chain specific acyl-CoA dehydrogenase, mitochondrial", "aln": "MAAALLARAGGSLGRALRARDWRRLHT----VYQSVELPETHQMLRQTCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPEELSGAGLDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKIGCFALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDMGRIGIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMALALESARLLTWRAAMLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEIYEGTSEIQRLVIAGHLLRSYRS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07417-1", "uniprot_id": "ACADS_MOUSE", "id": "Q07417-1", "name": "Short-chain specific acyl-CoA dehydrogenase, mitochondrial", "aln": "MAAALLARARGPLRRALGVRDWRRLHT----VYQSVELPETHQMLRQTCRDFAEKELVPIAAQLDREHLFPTAQVKKMGELGLLAMDVPEELSGAGLDYLAYSIALEEISRACASTGVIMSVNNSLYLGPILKFGSAQQKQQWITPFTNGDKIGCFALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDMGRIGIASQALGIAQASLDCAVKYAENRNAFGAPLTKLQNIQFKLADMALALESARLLTWRAAMLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEIYEGTSEIQRLVIAGHLLRSYRS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16219-1", "uniprot_id": "ACADS_HUMAN", "id": "P16219-1", "name": "Short-chain specific acyl-CoA dehydrogenase, mitochondrial", "aln": "MAAALLARASGPARRALCPRAWRQLHT----IYQSVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRLVIAGHLLRSYRS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDT1-1", "uniprot_id": "Q9VDT1_DROME", "id": "Q9VDT1-1", "name": "Short-chain specific acyl-CoA dehydrogenase, mitochondrial", "aln": "-MQSVLTRSLCIARRSLNARQIASLS----------ALSETHQMLQKSCRDFANNELSGNAAKFDREHLYPEKQIRQMGELGVMAVAIPEELGGTGLDYVAYAIAMEEISRGCASAGVIMSVNNSLYLGPLLSFGNDAQKKDYITPFTTGERVGCFALSEPGNGSDAGAASTIATDKGDHFVLNGTKAWITNAFEAEAAIVFATTNKQLKHKGISAFIVPKATKGFSLGKKEDKLGIRGSSTCQLIFEDCVVPKENMLGEPGFGFKIAMQTLDAGRIGIAGQALGIGQAALELAVDYAQKRQAFGKPIAKLQSIQQKIADMSLAMESARLLTWRAAWLKDQKQPYTKEAAMAKLAASEAATLCSHQCIQILGGMGYVTDMAAERHYRDARITEIYEGTSEIQRLVIAGSILKEYAS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGC2-1", "uniprot_id": "Q9VGC2_DROME", "id": "Q9VGC2-1", "name": "Short-chain specific acyl-CoA dehydrogenase, mitochondrial", "aln": "-MQQLIRVARTLGQRSSGAWSARIIAGGNRGIACLAALSETHQILQKTCREFANAELAPKARHHDREELYPAEQVRRLGELGLMSVTVREEYGGSGLDYQAYAIGMEEVARGDAAVSIVMGVNN-LYLGAVQQHGTEQQKQDFLVPYTQGEHIAFYALSEPGNGSDAGAASTTAKLQGDSYQINGTKAWISNSKEASGGIVFATVDKSMKHKGITAFLTPKDVPGLSIAKKESKMGMRATSTCQLVLEDVHVPRSRVLGAAGDGFKIAMQSLDCGRIGIAAQATGIAQAALELAVDYSQKRVAFGKHLARLQLIQQKLADMATRVEISRLLTWRAAWLKDNGLPITKEAAMAKLHASESATFCAHQCIQILGGMGYTTDLPAELYYRNARVTEIYEGTSEIQRIVIANAVLRELGKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *: : *.****:* ::**:**: ** * : *:*.*:* *::::* **:::: : ** .*:**** **:*.:**::*. *:..::*.*** ****.: ..*. **: ::.*:* *:::. :**************** * :** : :*******:*: **.. :***:.:: ::***:**:.* . *:::.***.*:*:*.:**.:*::** :*:. :** .* *******:** ******.** **.*::*: **.*:::* *** :::** ** *:***: :* :******** ***: * **:***** ***:** :**.*********.*::.** :**:**:************:***. :*:. . ", "identical_positions": 199, "similar_positions": 124, "identity": "47.72%" }, { "cls_id": "homologset.agr.RGD:620515", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQ09-1", "uniprot_id": "OLR1_MOUSE", "id": "Q9EQ09-1", "name": "Oxidized low-density lipoprotein receptor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTFDD-KMKPANDEPDQKSCGKKPKGLHLLSSPWWFPAAMTLVILCLVLSVTLIVQWTQLR---------------------QVSDLLKQYQANLTQQDRILEGQMLAQQKAENTSQESKKELKGKIDTLTQKLNEKSKEQEEL-----------------------------------------------LQKNQNLQEALQRAANSSEESQRELKGKIDTITRKLDEKSKEQEELLQMIQNLQEALQRAANSSEESQRELKGKIDTLTLKLNEKSKEQEELLQKNQNLQEALQRAANFSGPCPQDWLWHKENCYLFH-GPFSWEKNRQTCQSLGGQLLQINGADDLTFILQAISHTT-----SPFWIGLHRKKPGQPWLWENGTPLNFQFFKTRGVSLQLYSSGNCAYLQDGAVFAENCILIAFSICQKKTNHLQI-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70156-1", "uniprot_id": "OLR1_RAT", "id": "O70156-1", "name": "Oxidized low-density lipoprotein receptor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFDD-KMKPVNGQPDQKSCGKKPKGLHLLSSTWWCPAAVTLAILCLVLSVTLIVQQTQLL---------------------QVSDLLKQYQANLTQQDHILEGQMSAQKKAENASQESKRELKEQIDTLTWKLNEKSKEQEKL-----------------------------------------------LQQNQNLQEALQRAVNASEESKWELKEQIDILNWKLNGISKEQKELLQQNQNLQEALQKAEKYSEESQRELKEQIDTLSWKLNEKSKEQEELLQQNQNLQEALQRAANSSGPCPQDWIWHKENCYLFH-GPFNWEKSRENCLSLDAQLLQISTTDDLNFVLQATSHST-----SPFWMGLHRKNPNHPWLWENGSPLSFQFFRTRGVSLQMYSSGTCAYIQGGVVFAENCILTAFSICQKKANLLLTQ----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P78380-1", "uniprot_id": "OLR1_HUMAN", "id": "P78380-1", "name": "Oxidized low-density lipoprotein receptor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQLS---------------------QVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQ-------------------------------------------------------------------------------------------------------------------------------------------MELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFIQQAISYSS-----FPFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYPSGTCAYIQRGAVYAENCILAAFSICQKKANLRAQ-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPS1-1", "uniprot_id": "Q9VPS1_DROME", "id": "Q9VPS1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFKYDTYFLYLIVLLDPQ---GAQENNCPKVSLSERLEKRGEFSLVEFDPLLKFIVKN-------------------------PHKELLGEIEGLVGHTENKLQPMKSVIPNQSKALLN-YLDLHSKLEYLDAALQKAIN---------------------------------------------------------------------------------------------------------------------------------------------------SLQCSLKNTKVMSTGKPHPEFQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQLEAR-------WFWLDISNLVDKDQYIS-LATGKEVSYLKWRHGEPKKSSTANCAYLYAGDYYTYQCSDRNFFICQAV-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLM0-1", "uniprot_id": "Q9VLM0_DROME", "id": "Q9VLM0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYKYATCIFSIFALWNFWGVSAKKQD------------TSTGTNELPKAPMPYYTIEN-----------------------------IDMHQQHWFTYNSLRQNGTLWRIGNMEQRLEMRLQSFQNQMETKLRALKQQIEP-------------------------------------------------------------------------------------------------------------------------------------------------------YMENVKMSNKIKMSVFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFSEETKK-------KYWVDINSRANDGASWISTLSGRDVPFLKWKPN-LATNIHNHCVYINSNEMYFENCANDNYFACQAEQWA--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PFV8-1", "uniprot_id": "M9PFV8_DROME", "id": "M9PFV8-1", "name": "", "aln": "MCGSHKMWCCQVFILALFAHTIAVEFHGSAARAEINFEGPSPAHSQDTAAPTSRPKRRVYALCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDALSGENDPIWLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNSQPLDNNCAIYDPSLKYRWSARPCSDKLRFICQHKMPKVSGPNRYKIYNRWNATYPNEQANEVVLEILEPRENDRRYHRRVKAEDSDEEMIIPDRRRNNNRRNNHRNRQIKNQNQHPNDVNYQPAQQRQRNRPRTSTVAPTTTQSVSQSNDVLAPSPTPQQMTQYDRKLQRQRERERRRQLRRQERQKLAREQKRERQRRLKEERQRLQREEQQRRQRLHHDEPKPQVNPQVKPQVIDELRQRSGEDLDKNQTDEHEQKLRNEQEKKLREEQQKQRDEQEQKDREEQDRLKQEEEQARTHQKELKENQEQQLRELKAKQEREKQERDYQQQKREHELELLKQRQAEADRQHAADEEAEKLRLERIQKQRELEAQQRREREEQRRKQREEQEEQDRQNHAKRLAEEKRLHDLYAERIRLANTEREKQLAEAHEAKRLEELKLQEQLKKQEDERQEQIRREQEEEEKRLELERLEEARRFEEKELKRLHEENQRREEQKLQREREIALREAAEKKLAEEEEMLRKEVAEEERKVKQRLEDEMRQAEEARKAKEAEERAAEEAKAAEQKRRVEAAKKKADEEVKAKLEEKRREYVTRISALSPEDQKKFIEMRKRRKQLKEKKERDQRAKELKRIQQAMRLDDNE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : . : . . : .: .:: : *: : . . : . :. .: : : . : *: : : ", "identical_positions": 2, "similar_positions": 33, "identity": "0.25%" }, { "cls_id": "homologset.agr.RGD:620516", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60905-1", "uniprot_id": "DNJC5_RAT", "id": "P60905-1", "name": "DnaJ homolog subfamily C member 5", "aln": "-MADQ-RQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVVCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVS-PE------DLEAQL-------------------------QSDEREATDTPIVIQPAS--------------ATETTQLTADS-HPSYHTDGFN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60904-1", "uniprot_id": "DNJC5_MOUSE", "id": "P60904-1", "name": "DnaJ homolog subfamily C member 5", "aln": "-MADQ-RQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVVCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVS-PE------DLEAQL-------------------------QSDEREATDTPIVIQPAS--------------ATETTQLTADS-HPSYHTDGFN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3Z4-1", "uniprot_id": "DNJC5_HUMAN", "id": "Q9H3Z4-1", "name": "DnaJ homolog subfamily C member 5", "aln": "-MADQ-RQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVS-PE------DLEAQL-------------------------QSDEREATDTPIVIQPAS--------------ATETTQLTADS-HPSYHTDGFN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FF34-1", "uniprot_id": "E7FF34_DANRE", "id": "E7FF34-1", "name": "DnaJ homolog subfamily C member 5", "aln": "-MAEQQRQRALSTSGESLYVVLGVEKNTAQEDIKKSYRKLALKFHPDKNPNNPEAADKFKEINNAHAILSDPTKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFIFCGVATGCYFCCCLCCCCNCCCGKCKPHPPHSDDPDFYVS-PE------DLEAQM-------------------------QSDERDGS-SPIMMQPSS--------------ATESTQLTADSHHTSYRTDANY---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03751-1", "uniprot_id": "DNJC5_DROME", "id": "Q03751-1", "name": "DnaJ homolog subfamily C member 5 homolog", "aln": "MSAPGMDKRKLSTSGDSLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKAVVICCAVITGCCCCCCCCCCCNFCCGKFKPPVNESHDQYSHLNRPDGNREGNDMPTHLGQPPRLEDVDLDDVNLGAGGAPVTSQPREQAGGQPVFAMPPPSGAVGVNPFTGAPVAANENTSLNTTE-QTTYTPDMVNQKY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* *****:*** :**: *.:: :****:*******:******:* :*******:*.**:**:* *******:*******:**********:***::* .**:.: *.: * * *** *** * **** ** ...: ::. *: *: ::: *. *: . . : : *.* *.*.*.*.: . :.:* .* ", "identical_positions": 102, "similar_positions": 56, "identity": "40.8%" }, { "cls_id": "homologset.agr.RGD:620517", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80U96-1", "uniprot_id": "XPO1_RAT", "id": "Q80U96-1", "name": "Exportin-1", "aln": "-----------MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKAKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQ----YEEQFETLFTLTMMQLKQ-MLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHGQLLEKRLNLREALMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESP--FSTSASPLLSGSQ----------------HFDIPPRRQLYLTVLSKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTEIIMTKKLQNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPLLDAVLIDYQR-NVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPAQFKLVLDSIIWAFKHTMRNVADTGLQILFTLLQNVAQEEAA--AQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISTPLNPG----SPVSNQMFIQDYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEERETALRQAQEEKHKLQMSVPGILNPHEIPEEMCD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P5F9-1", "uniprot_id": "XPO1_MOUSE", "id": "Q6P5F9-1", "name": "Exportin-1", "aln": "-----------MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKAKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQ----YEEQFETLFTLTMMQLKQ-MLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHGQLLEKRLNLREALMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESP--FSTSASPLLSGSQ----------------HFDIPPRRQLYLTVLSKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTEIIMTKKLQNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPLLDAVLIDYQR-NVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPAQFKLVLDSIIWAFKHTMRNVADTGLQILFTLLQNVAQEEAA--AQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISTPLNPG----NPVNNQMFIQDYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEERETALRQAQEEKHKLQMSVPGILNPHEIPEEMCD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14980-1", "uniprot_id": "XPO1_HUMAN", "id": "O14980-1", "name": "Exportin-1", "aln": "-----------MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQ----YEEQFVTLFTLTMMQLKQ-MLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESP--FSTSASPLLSGSQ----------------HFDVPPRRQLYLPMLFKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKLHNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPLLDAVLIDYQR-NVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTLLQNVAQEEAA--AQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISTSLNPG----NPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HRQ1-1", "uniprot_id": "A0AC58HRQ1_DANRE", "id": "A0AC58HRQ1-1", "name": "Exportin-1", "aln": "MAGVMIMSPSSMPAIMTMLADHAARQLLDFNQKLDINLLDNVVNCLYHGVGPQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYALQILETVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDAANVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMIILKLLSEEVFDFSSGQMTQVKAKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLVYKFLNVPMFRNVTLKCLTEIAGVSVSQ----YEEQFVNLFTLTMMQLKQ-MLPLNTNIRLAYANGKDDEQNFIQNLSLFLCTFLKEHGQLIEKRLNLRETLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESP--FSTSTSPLLSGSQ----------------HFDVPPRRQLYLPVLSKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYADTERIMTEKLHNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQAVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNVYKCLSENISAAIQTNGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVGENFVPPLLDAVLIDYQR-NVPAAREPEVLSTMATIVNKLGGHITGEIPQIFDAVFECTLNMINKDFEEYPEHRTHFFYLLQAVNSHCFPAFLAIPPAQFKLVLDSIIWAFKHTMRNVADTGLQILYTLLQNVAQEEAA--AQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISTTLNPS----NPVNNQVFIQEYVANLLKSAFPHLQDAQVKVFVTGLFSLNQDIAAFKEHLRDFLVQIKEFAGEDTSDLFLEEREASLRQAQEEKHKLQMSVPGILNPHEIPEEMCD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9TVM2-1", "uniprot_id": "XPO1_DROME", "id": "Q9TVM2-1", "name": "Exportin-1", "aln": "--------------MATMLTSDEAGKLLDFSQKLDINLLDKIVEVVYTAQGEQLRLAQSILTTLKEHPEAWTRVDSILEYSQNQRTKFYALQILEEVIKTRWKVLPRNQCEGIKKYVVSLIIKTSSDPIVMEQNKVYLNKLNMILVHILKREWPRNWETFISDIVGASKTNESLCMNNMVILKNLSEEVFDFSQGQITQTKAKHLKDTMCSEFSQIFTLCSFVLENSMNAALIHVTLETLLRFLNWIPLGYIFETQQIETLIFKFLSVPMFRNVTLKCLSEIAGLTAAN----YDENFATLFKDTMVQLEQ-IVGQNMNMNHVFKHGSDTEQELVLNLAMFLCTFLKEHGKLVED-AKYVDYLNQALMYLVMISEVEDVEVFKICLEYWNSLVEDLYN------SEFFHPTLESTK----------------RQQVYPRRRFYAPILSKVRFIMISRMAKPEEVLVVENENGEVVREFMKDTNSINLYKNMRETLVFLTHLDSVDTDRIMTLKLLNQVNGSEFSWKNLNTLCWAIGSISGAFCEEDEKRFLVTVIKDLLGLCEQKKGKDNKAIIASNIMYVVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAIKCRRYFVTIQPNEACTFIDEILTTMSSIICDLQPQQVHTFYEAVGYMISAQVDQVQQDVLIERYMQLPNQVWDDIISRASKNVDFLKNMTAVKQLGSILKTNVAACKALGHAYVIQLGRIYLDMLNVYKITSENIIQAIEVNGVNVNNQPLIKTMHVVKKETLNLISEWVSRSNDNQLVMDNFIPPLLDAILLDYQRCKVPSAREPKVLSAMAIIVHKLRQHITNEVPKIFDAVFECTLDMINKNFEDFPQHRLSFYELLQAVNAHCFKAFLNIPPAQFKLVFDSVVWAFKHTMRNVADMGLNILFKMLQNLDQHPGA--AQSFYQTYFTDILMQIFSVVTDTSHTAGLPNHAIILAYMFSLVENRKITVNLGP------IPDNMIFIQEYVASLLKSAFTHLSDNQVKVFVTGLFNLDENVQAFKEHLRDFLIQIREATGEDDSDLYLEEREAALAEEQSNKHQMQRNIPGMLNPHELPEDMQDE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P30822-1", "uniprot_id": "XPO1_YEAST", "id": "P30822-1", "name": "Exportin-1", "aln": "-----------------------MEGILDFSNDLDIALLDQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTNPQSKFIALSILDKLITRKWKLLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPQNWPEFIPELIGSSSSSVNVCENNMIVLKLLSEEVFDFSAEQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQGSSSSLIVATLESLLRYLHWIPYRYIYETNILELLSTKFMTSPDTRAITLKCLTEVSNLKIPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKATYANANGNDQSFLQDLAMFLTTYLARNRALLESDESLRELLLNAHQYLIQLSKIEERELFKTTLDYWHNLVADLFYEVQRLPATEMSPLIQLSVGSQAISTGSGALNPEYMKRFPLKKHIYEEICSQLRLVIIENMVRPEEVLVVENDEGEIVREFVKESDTIQLYKSEREVLVYLTHLNVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSEDTEKRFVVTVIKDLLDLTVKKRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDTFIKIVQKCKYHFVIQQPRESEPFIQTIIRDIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLMQLPNMAWDTIVEQSTANPTLLLDSETVKIIANIIKTNVAVCTSMGADFYPQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYISKARNLDDVVKVLVEPLLNAVLEDYMN-NVPDARDAEVLNCMTTVVEKVGHMIPQGVILILQSVFECTLDMINKDFTEYPEHRVEFYKLLKVINEKSFAAFLELPPAAFKLFVDAICWAFKHNNRDVEVNGLQIALDLVKNIERMGNVPFANEFHKNYFFIFVSETFFVLTDSDHKSGFSKQALLLMKLISLVYDNKISVPLYQEAEVPQGTSNQVYLSQYLANMLSNAFPHLTSEQIASFLSALTKQYKDLVVFKGTLRDFLVQIKEVGGDPTDYLFAEDKENALMEQNRLEREKAAKIGGLLKPSELDD-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***.:.*** ***::*. .* . * * : **.:** ::::*:** :.* **::* * .:*: .*.**: :*. :**:**.:: **:::**.:**. ..* .: :* :.* :: **:***:***::* **.:::*:* :. .:* ***::** ********* *:**.*: ***::*..**.*** ** *:*:. .:.*: .***:***:*:*** **:**: :. * **:. * * ::****:*::.:. .: ..: :* *: *: :: . ::. .: :... :*.:: :*::** *:* .: *:*. . : * :* *:: :*::*: *:** *:**: *. :*: : * :. : . ::::* : ::*::::..*.:*********::**:****:*::::*:***. **.**:****: **: ** ** .*::*:*:**:*:***.********:: *: ****:********.* :*:******::**:***:********:***:**:**: **********:*************. **: :** * * .**: *: :.. .***********:* * :*. : . . :: *:. * *** .** *:.::: * :* : :** :..*:**** .*.::* : ***:** :**::*: *. * : .:* ..: * :: ::.:*:* *:*:. ::*::.: : * . :: ***:*:* ** . :** **:.:**. *: :*.*: *. : *:::******:****:* ::*:** *: **:.:* :.* *** :**: ***..*:: *****. *:* **:* :::*: : . *:.*::.** :: . * *:**:.*.:*:. :* :* ::.** : **:. * .* :::.:*:*.:*..**.** . *: *::.* . ::: .** *****:**:* *: . *: *::* :* : : ::: .: *:::* *: : ", "identical_positions": 419, "similar_positions": 380, "identity": "37.65%" }, { "cls_id": "homologset.agr.RGD:620518", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70611-1", "uniprot_id": "DOC2A_RAT", "id": "P70611-1", "name": "Double C2-like domain-containing protein alpha", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MRGRRGDRMTINIQEHMAINVCPG---------------PIRPIRQISDYFPRRGPGPE-------------GGGG--GRGFGEAPAHLAPLALAPP-----------------------------------------------------------AALLGATTPDDGAEVDSYDSDDT-------------------TALGTLEFDLLYDQASCMLHCRILRAKGLKPMDFNGLADPYVKLHLLPGACKAN---KLKTKTQRNTLNPVWNEELTYSGITDDDITHKVLRISVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLPSPSSMSAALRGISCYLKELEQAEQGPGLLEERGRILLSLSYS---------SRRHGLLVGIVRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEMELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGP-GARGEAQKHWRDCLHQPDTAVERWHTLTSELPPAAGALPLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TNF0-1", "uniprot_id": "DOC2A_MOUSE", "id": "Q7TNF0-1", "name": "Double C2-like domain-containing protein alpha", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MRGRRGDRMTINIQEHMAINVCPG---------------PIRPIRQISDYFPRRGPGPE-------------GGGGGGGTGCGEAPAHLAPLALAPP-----------------------------------------------------------AALLGATTPDDGAEVDSYDSDDT-------------------TALGTLEFDLLYDQASCMLHCRILRAKGLKPMDFNGLADPYVKLHLLPGACKAN---KLKTKTQRNTLNPVWNEELTYSGITDDDITHKVLRISVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLPSPSSMSAALRGISCYLKELEQAEQGPGLLEERGRILLSLSYS---------SRRHGLLVGIVRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGP-GARGEAQKHWNDCLHQPDTALERWHTLTSELPPAAGAYPLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14183-1", "uniprot_id": "DOC2A_HUMAN", "id": "Q14183-1", "name": "Double C2-like domain-containing protein alpha", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MRGRRGDRMTINIQEHMAINVCPG---------------PIRPIRQISDYFPR-GPGPE-------------GGGG----GGGEAPAHLVPLALAPP-----------------------------------------------------------AALLGATTPEDGAEVDSYDSDDA-------------------TALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKAN---KLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYS---------SRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGP-GARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J1H0-1", "uniprot_id": "A0AC58J1H0_DANRE", "id": "A0AC58J1H0-1", "name": "", "aln": "----------------------------------------------------------------------------------------MWWCVDQSSVKAGGLWIESQNQLIFTEQGLWVRLRICFP-----LWERNYSSATQRVSPEYNSSSMTVRKGKKLTISIQEHMAIDVCPG---------------PIRPIRQISAYFPRLSPTAEPVSPNPASPLSLSPGLGASGGASGGLLSPLQAGARGGG-----------------------------------------------------------GTLSAASSIETSVDICSSDSDDS-------------------TALGTLEFELRYEKATSSLNCTIIRAKGLKPMDFNGLADPYVKLHLLPGACKAN---KLKTKTVRNSLNPVWNETLTYVGITEEDMHRKTLRLSVCDEDKLTHNEFIGESRVALRRVKPDQTKRFYTCLEHPPPLPSPTAMGAALRGISCYLREWENEQMTS--LEERGRLLLSLQFLPPPAEGEGESRRGGLCVGVLRCAHLAAMDVNGFSDPYVKIYLKPDVKKKSKHKTSVIKKTLNPEFNEEFFYEISLSELVHKTLEVTVWDYDLGRSNDFIDSTRYWKYSSEVLVHNSITQLLQMCRLHIHDVNLPFHHIPKVLYWIEIW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2R9-1", "uniprot_id": "Q9W2R9_DROME", "id": "Q9W2R9-1", "name": "", "aln": "MDFQNRNNTANKFVCPSDRQLALRAKLKAGWSSSKTSEPLRPEEQEAIISVIRRNEEIEVAERQRVGRLVERVEKIKQHAVERGPNCCRLCGDTFGILRPQRILCEDCRQSVCTKCSVDINIRYHTSERSREIWLCRICSETREMWKKSGAWFFKGLPKYDMPRSASATPIPNPGPGSMAGDTRAVQSCHATPTRPARVKKLTIRVNDSSSSSSGHSEPEDEVDTGVGIGVGVVGGGMAKGIASTRLQREDSFRLRAYGSIRSFIDGGERKLSNSFFFNRQQSQRPSECPEYDSVSMSKLRRESSFLRRGSVSSSWSISDSSGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYGH-DFLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWP---------------------NGKMLLSLCYN---------TKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGA-QSKGERLQQWLDCIRLPDHFHEKWHCLAPDNPAH-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. . . : ** * ** * . : .. .. * : . .:: .: : . . * :*.:: . ** **: : * .* *.* ::**:.* .** ****** **:::. .::: :*** ::: ** :** * : *: ::: .. : ::: *:** * :*:* :* * ::. . :: * ...: *. .*::**** : ::* .* *.: :* :* *** ** ***:** *:**..*:.****.* :**** :****::* . * : * :**** *:*:****:.. :. : : :: . : . * ", "identical_positions": 100, "similar_positions": 114, "identity": "14.77%" }, { "cls_id": "homologset.agr.RGD:620519", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70610-1", "uniprot_id": "DOC2B_RAT", "id": "P70610-1", "name": "Double C2-like domain-containing protein beta", "aln": "-----------------------------------------------------------MTLRRRGEKATISIQEHMAIDVCPGP------------IRPIKQISDYFPR------------------------------------------FPRGLPPTAAPRASAPPDAPARSPAATA---------------------------GPRSPSDGARDDDEDVDQ-----------------------------------------------------------------LFGAYGASPGPSPGPSPVRPPAKPPEDEPDADGYESDDC----------------------TALGTLDFSLLYDQENNALHCTISKAKGLKPMDHNGLADPYVKLHLLPGASKAN---KLRTKTLRNTLNPSWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQLPVDKAEDKSLEE-RGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKTLEVTVWDYDIGKSNDFIGGVVLGINAKGERLKHWFDCLKNKDKRIERWHTLTNEIPGAVLSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70169-1", "uniprot_id": "DOC2B_MOUSE", "id": "P70169-1", "name": "Double C2-like domain-containing protein beta", "aln": "-----------------------------------------------------------MTLRRRGEKATISIQEHMAIDVCPGP------------IRPIKQISDYFPR------------------------------------------FPRGLPPTAAPRAPAPPDAPARSPAASA---------------------------SPRSPSDGARDDDEDVDQ-----------------------------------------------------------------LFGAYGASPGPSPGPSPARPPAKPPEDEPDVDGYESDDC----------------------TALGTLDFSLLYDQENNALHCTISKAKGLKPMDHNGLADPYVKLHLLPGASKAN---KLRTKTLRNTLNPSWNETLTYYGITDEDMVRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQLPVDKAEDKSLEE-RGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKTLEVTVWDYDIGKSNDFIGGVVLGINAKGERLKHWFDCLKNKDKRIERWHTLTNELPGAVLSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14184-1", "uniprot_id": "DOC2B_HUMAN", "id": "Q14184-1", "name": "Double C2-like domain-containing protein beta", "aln": "-----------------------------------------------------------MTLRRRGEKATISIQEHMAIDVCPGP------------IRPIKQISDYFPR------------------------------------------FPRGLPPDAGPRAAAPPDAPARPAVAGA---------------------------GRRSPSDGAREDDEDVDQ-----------------------------------------------------------------LFGAYGSSPGPSPGPSPARPPAKPPEDEPDADGYESDDC----------------------TALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKAN---KLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQLPVDKTEDKSLEE-RGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTSELPGAVLSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ASV5-1", "uniprot_id": "A0A8M3ASV5_DANRE", "id": "A0A8M3ASV5-1", "name": "Double C2-like domain-containing protein", "aln": "-----------------------------------------------------------MTQRK-GEKTTISIQEHMAIDVCPGP------------IQPIKQISDYFPR------------------------------------------YPRGLPPTAPP--ALSRAGSLRSSSTSQ---------------------------KSEGPQADANRDEDDLDQ-----------------------------------------------------------------AFGATALVASKK-------------EEEPDVEGYDSDDS----------------------TTLGTLDFSLLYDQENNALHCTINKAKGLKPMDHNGLSDPYVKLHLLPGASKAN---KLRTKTLRNTLNPVWSETLTYYGITDEDMVRKTLRISVCDEDKFRHNEFIGETRIPLKKLKPNQTKNFSNCLEKQLPIDKTDDKSLEE-RGRIMISLKYSSQKSGLVVGIIRCAHLAAMDANGFSDPYVKTYLKPDENKKSKHKTAVKKKTLNPEFNEEFFYEIKYADLSKKTLEVTVWDYDIGKSNDFIGGVSLGINASGERLKHWFDCLKNKDKKIERWHTLTNELPGSGYND", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2R9-1", "uniprot_id": "Q9W2R9_DROME", "id": "Q9W2R9-1", "name": "", "aln": "MDFQNRNNTANKFVCPSDRQLALRAKLKAGWSSSKTSEPLRPEEQEAIISVIRRNEEIEVAERQRVGRLVERVEKIKQHAVERGPNCCRLCGDTFGILRPQRILCEDCRQSVCTKCSVDINIRYHTSERSREIWLCRICSETREMWKKSGAWFFKGLPKYDMPRSASATPIPNPGPGSMAGDTRAVQSCHATPTRPARVKKLTIRVNDSSSSSSGHSEPEDEVDTGVGIGVGVVGGGMAKGIASTRLQREDSFRLRAYGSIRSFIDGGERKLSNSFFFNRQQSQRPSECPEYDSVSMSKLRRESSFLRRGSVSSSWSISDSSGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYGH-DFLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPNGKMLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCLAPDNPAH----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *: : . ::: * ** ::* : :.: : : :*** * . . . . : ... . ::::* :.: . . .* .* *::. . ** *:::: * : ::*.**: :*:.* .** **:*** **:::. :::: ****:::* ** :.*** : *: *:: .. : ::: *:**: * :*:* ::: *..::.. :* * : .:: : : : .*::::** *.::: .*:*.: :* :* *** ** ***:** *:** .*:.****:** :**** :**** :* . ** *: * :**** *:******:*.: ** ::.****::*:**:: *: *:** *: : *. ", "identical_positions": 120, "similar_positions": 143, "identity": "18.66%" }, { "cls_id": "homologset.agr.RGD:62052", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2BA47-1", "uniprot_id": "A0A8M2BA47_DANRE", "id": "A0A8M2BA47-1", "name": "", "aln": "------------------------------------------------------------------------------------------MFMNRKK--MTSSRRHHLKSLVLSIAFNLLDAEAKQHIADKESHMSENCP-ALDLPGS-VQELQDLCKKLHQQIDKVDEERYDMEAKVAKADKEIEDLKIKVIDLKGKFKKPALKKVRMSADAMLQALLGSKHKVSMDLRANLKQVKK-EVKEESV--EQVGDWRKNIEDKAGMDGRKKMFESEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1QCC0-1", "uniprot_id": "F1QCC0_DANRE", "id": "F1QCC0-1", "name": "", "aln": "--------------------------------------------------------------------------------------------MSEKK--MTSSRRHHLKSLLLQIAHGLLEEEAAAAEEEKQRYMEENCP-SLSLPGS-LQELQELCRKMHQQIDMVDEQRYDMETKVAKSDKEIEDLKIKVQDLKGKFKKPVLKKVRMSADAMLQALLGSKHKVSLDLRANLKQVKK-EVKEEEK--EAVGDWRKNIEDKAGMDGRKKMFESEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32THC7-1", "uniprot_id": "A0AB32THC7_DANRE", "id": "A0AB32THC7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------MSEKR--LSSSKKHSLKSMMLQVAKDLLEAEAVEKKEERKRYMEEHCP-AFSCPSS-KQELEEFCRKLHEKIEVIDEERYVLEHKATMVVNEVKDLNIKIVDLKGKFKKPPLKKVRMSADAMLQALLGSKHKVSMDLRANLKQVKK-EVKEENKDLRDVGDWRKNIEDKTGMGGRKKMFESEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P23693-1", "uniprot_id": "TNNI3_RAT", "id": "P23693-1", "name": "Troponin I, cardiac muscle", "aln": "--------------------------------------------------------MADESSDAAGEPQPAPAPVRRRSSANYRAYATEPHAKKKSK--ISASRKLQLKTLMLQIAKQEMEREAEERRGEKGRVLSTRCQ-PLVLDGLGFEELQDLCRQLHARVDKVDEERYDVEAKVTKNITEIADLTQKIYDLRGKFKRPTLRRVRISADAMMQALLGTRAKESLDLRAHLKQVKK-EDIEKEN--REVGDWRKNIDALSGMEGRKKKFEG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48787-1", "uniprot_id": "TNNI3_MOUSE", "id": "P48787-1", "name": "Troponin I, cardiac muscle", "aln": "--------------------------------------------------------MADESSDAAGEPQPAPAPVRRRSSANYRAYATEPHAKKKSK--ISASRKLQLKTLMLQIAKQEMEREAEERRGEKGRVLRTRCQ-PLELDGLGFEELQDLCRQLHARVDKVDEERYDVEAKVTKNITEIADLTQKIYDLRGKFKRPTLRRVRISADAMMQALLGTRAKESLDLRAHLKQVKK-EDIEKEN--REVGDWRKNIDALSGMEGRKKKFEG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19429-1", "uniprot_id": "TNNI3_HUMAN", "id": "P19429-1", "name": "Troponin I, cardiac muscle", "aln": "--------------------------------------------------------MADGSSDAAREPRPAPAPIRRRSS-NYRAYATEPHAKKKSK--ISASRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQ-PLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKK-EDTEKEN--REVGDWRKNIDALSGMEGRKKKFES--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36188-1", "uniprot_id": "TNNI_DROME", "id": "P36188-1", "name": "Troponin I", "aln": "MADDEKKAAAPAAAPAAAAKPAAPAAAPAANGKAAPAANGKAAPAAAAAPAGPPKDPNDPKVKAEEAKKAKQAEIERKRAEVRKRMEEASKAKKAKKGFMTPERKKKLRLLLRKKAAEELKKEQERKAAERRRIIEERCGSPRNLSDASEGELQEICEEYYERMYICEGQKWDLEYEVRKKDWEINDLNAQVNDLRGKFVKPALKKVSKYENKFAKLQK---KAAEFNFRNQLKVVKKKEFTLEEEEKEKKPDWSK---GKPGDAKVKEEVEAEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: ::..:: *: :: . * :. * :: : .* . . **:::*.: : :: : ::: :* :. *: **. :: **:*** :* *::* : : : .:::* :** *** * :. . ** * .* *: .*. ", "identical_positions": 32, "similar_positions": 59, "identity": "11.64%" }, { "cls_id": "homologset.agr.RGD:620520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35767-1", "uniprot_id": "NKX25_RAT", "id": "O35767-1", "name": "Homeobox protein Nkx-2.5", "aln": "--------------------------MFPSPALTHTPFSVKDILNLEQQQRSLAAG----DLSARLEATLAP-ASCMLAAFKPDGYSG-PEAAAPGLAELRAELGP-APSPPKCSPAFPTAPTFYPRAYGDPDPAKDPRADK--KELCALQKAVELDKAETDGAERRRPRRRRKPRVLFS-----QAQVY--------ELERRFKQQRYLSPA---ERDQLASVLKLTSTQVKIWFQ--NRRYKCKRQRQDQTLELLG---PPPPPARRIAVPVLVRDGKPCLGDSAAYAPAYGLGLNAYGYNAYP-YPGYGGAACSPAYSC-AAYPAAP----------PAAHAPAASANSNFVN-------FGVGDLNTVQSPGMPQGNSGVSTLHGIRAW-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42582-1", "uniprot_id": "NKX25_MOUSE", "id": "P42582-1", "name": "Homeobox protein Nkx-2.5", "aln": "--------------------------MFPSPALTPTPFSVKDILNLEQQQRSLASG----DLSARLEATLAP-ASCMLAAFKPEAYSG-PEAAASGLAELRAEMGP-APSPPKCSPAFPAAPTFYPGAYGDPDPAKDPRADK--KELCALQKAVELDKAETDGAERPRARRRRKPRVLFS-----QAQVY--------ELERRFKQQRYLSAP---ERDQLASVLKLTSTQVKIWFQ--NRRYKCKRQRQDQTLELLG---PPPPPARRIAVPVLVRDGKPCLGDPAAYAPAYGVGLNAYGYNAYP-YPSYGGAACSPGYSC-AAYPAAP----------PAAQPPAASANSNFVN-------FGVGDLNTVQSPGMPQGNSGVSTLHGIRAW-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52952-1", "uniprot_id": "NKX25_HUMAN", "id": "P52952-1", "name": "Homeobox protein Nkx-2.5", "aln": "--------------------------MFPSPALTPTPFSVKDILNLEQQQRSLAAAG---ELSARLEATLAP-SSCMLAAFKPEAYAG-PEAAAPGLPELRAELGR-APSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEK--KELCALQKAVELEKTEADNAERPRARRRRKPRVLFS-----QAQVY--------ELERRFKQQRYLSAP---ERDQLASVLKLTSTQVKIWFQ--NRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPAYGVGLNPYGYNAYPAYPGYGGAACSPGYSCTAAYPAGP----------SPAQPATAAANNNFVN-------FGVGDLNAVQSPGIPQSNSGVSTLHGIRAW-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UZK3-1", "uniprot_id": "A0A8N7UZK3_DANRE", "id": "A0A8N7UZK3-1", "name": "Homeobox protein Nkx-2.5", "aln": "------------------------MAMFSS-QMTSTPFSVRDILNLEQNQEDMVSL----DMSQRLDSALIPTSSCMLSTFKQEQFMEMPSGSSLFSEDLQEDKGN-KINSINFSASGFYAKNFLEMDYVKDAKTDDTFEDKEKKDIGCCQEDPGED-LKLDDAERPKQRKRRKPRVLFS-----QAQVY--------ELERRFKQQKYLSAP---ERDHLANVLKLTSTQVKIWFQ--NRRYKCKRQRQDQTLEMVG-----IAPPRRISVPVLVRDGKPCLGDTSTYNTSYNVGINHFTYNTYPAFSNFPSPGNS-NYSC--NYPSSM----------SSIQP--SQSNSNYMN-------FGVGDLNNVQAS---FQSSSVPSLHGIRAW-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22711-1", "uniprot_id": "TIN_DROME", "id": "P22711-1", "name": "Muscle-specific homeobox protein tinman", "aln": "MLQHHQQQAQSGGYYDHYTQSPSPGSLTNADALNTTPFSVKDILNMVNQTEAYEGSYGHIDGAATASALFAAGEYQNPHQYLNHQQHQQSELPIPQQQLHHQHLDDGATTSSSLSPLLPPPPHQLYGGYQDYGMPAHMFQHHHGHPHQSFQHSASAYNMSASQFYAGASATAYQTPATYNYNYAGSGEVYGGATPSAVGIKSEYIPTPYVTPSPTLDLNSSAEVDSLQAPTQKLCVNPLSQRLMETASNSSSLRSIYGSDEGAKKKDNSQVTSSRSELRKNSISGNSNPGSNSGSTKPRMKRKPRVLFSQAQVLELECRFRLKKYLTGAEREIIAQKLNLSATQVKIWFQNRRYKSKRGDIDCEGIAKHLKLKSEPLDSPTSLPPPIPNHVMWPPTMQQSQQQQQHHAQQQQMQHM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. *****:****: :: . . : : .: : . : . .. . : . . .. . :. . * . . . .: : . *. . . :. . :. ..:** :: .: *::.. : : *.* .* :. *: .: .:* . ..... .: * . .. . * .:.. : . . :. :. . : ... .. : * .: . *:.. ::: .* ..: . * ", "identical_positions": 25, "similar_positions": 112, "identity": "6.01%" }, { "cls_id": "homologset.agr.RGD:620521", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58195-1", "uniprot_id": "PLS1_RAT", "id": "P58195-1", "name": "Phospholipid scramblase 1", "aln": "MEKHGPPEHAAYPIPQADYQGS-------QGPY-------PGPQGP-------------YPGPQGP---------YAGPQGPYPGPQGPYAGPQGP------YPGPQPGYPVPPGS---YAGGDPS-----GFP-------------------VQHQ-----PAYNHPGGPGGTP-------WMQAPPPPLDCPPGLEYLTQIDQILVHQQIELLEVLTGFETNNKYEIKNSLGQRVYFAVED----TDCCTRNCCGASRPFTLRILDNMGREVMTLERPLRCSSCCFPCCLQEIEIQAP-----------PGVPVGYVIQTWHPCLPKFTLQNEKRQDVLKVVGPCVVCSCCSDIDFELKSLDEESVVGKISKQWSGFVREAFTDADNFGIQFPLD----------------LDVKMKAVMLGACFLIDFMFFERTGNEEQ-RSGVW-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJ00-1", "uniprot_id": "PLS1_MOUSE", "id": "Q9JJ00-1", "name": "Phospholipid scramblase 1", "aln": "MENHSKQTEAPHPG---TYMPA-------GYPP-------PYPPAA-------------FQGPSD--------------HAAYPIPQAGYQGPPGP------YPGPQPGYPVPPGG---YAGGGPS-----GFP-------------------VQNQ-----PAYNHPGGPGGTP-------WMPAPPPPLNCPPGLEYLAQIDQLLVHQQIELLEVLTGFETNNKYEIKNSLGQRVYFAVED----TDCCTRNCCGASRPFTLRILDNLGREVMTLERPLRCSSCCFPCCLQEIEIQAP-----------PGVPVGYVTQTWHPCLPKFTLQNEKKQDVLKVVGPCVVCSCCSDIDFELKSLDEESVVGKISKQWSGFVREAFTDADNFGIQFPLD----------------LDVKMKAVMLGACFLIDFMFFERTGNEEQ-RSGAWQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15162-1", "uniprot_id": "PLS1_HUMAN", "id": "O15162-1", "name": "Phospholipid scramblase 1", "aln": "MDKQNSQMNASHPE---TNLPV-------GYPP-------QYPPTA-------------FQGPPG------------------------YSG----------YPGPQVSYPPPPAG---HSGPGPA-----GFP-------------------VPNQPVYNQPVYNQPVGAAGVP-------WMPAPQPPLNCPPGLEYLSQIDQILIHQQIELLEVLTGFETNNKYEIKNSFGQRVYFAAED----TDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAP-----------PGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLD----------------LDVKMKAVMIGACFLIDFMFFESTGSQEQ-KSGVW-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DCW2-1", "uniprot_id": "PLS2_MOUSE", "id": "Q9DCW2-1", "name": "Phospholipid scramblase 2", "aln": "-------MEAPRSG---TYLPA-------GYAP-------QYPPAA-------------VQGPPE--------------HTGRPTFQTNYQVPQSG------YPGPQASYTVSTSG---HEGYAAT-----RLP-------------------IQNN---------QTIVLANTQ-------WMPAPPPILNCPPGLEYLNQIDQLLIHQQVELLEVLTGFETNNKFEIKNSLGQMVYVAVED----TDCCTRNCCEASRPFTLRILDHLGQEVMTLERPLKCSSCCFPCCLQEIEIQAP-----------PGVPIGYVTQTWHPCLPKLTLQNDKRENVLKVVGPCVACTCCSDIDFEIKSLDEVTRIGKITKQWSGCVKEAFTDSDNFGIQFPLD----------------LEVKMKAVTLGACFLIDYMFFEGCE---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VT88-1", "uniprot_id": "Q9VT88_DROME", "id": "Q9VT88-1", "name": "Phospholipid scramblase", "aln": "MKSNVNQGGYAPPGFGSGFQPNAPPAEGFGYPPPTGGHNAPYPPAPGHPQPPPPTNYGFMPGPQPAGYAPVPQMPPYGEAPPYGAGQPPYMGGPGGQPPYAGGPGGQPPYVGGPGGQPHYGGGAPPPQAFGGYPPGPAGPGGPPNAFGGYPPGQPQQPIVTQPGMGPGMGPGMAPQGGPAGDWMSIPTGIPNCPRGLEYLTTIDQLLVKQKVELLEAFTGFETNNKFTIKNALGQKVYFAAED----NDCCTRNCCGPARPFDMRVFDNFQQEVIHMHRPLACSSCLFPCCLQSIEVSAP-----------PGNVIGTIEQEWSICSPSFRILNHVGDTVMRIEGPFCTFSLCGDVEFNVVSLTG-EKIGKISKQWSGLAREIFTDADFFGINFPLD----------------LDVRMKAVLLGATFLIDAMFFEKAGNQETDRPGML-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47140-1", "uniprot_id": "AIM25_YEAST", "id": "P47140-1", "name": "Altered inheritance rate of mitochondria protein 25", "aln": "MHRTAIFLTYRSCMRNFSTLSK------------------TLTVSS---------------GKVIR-------------------------------------NGPFRRVIREKNQ----ITKAPS-----------------------------------VKAFKENSNSGIIK------VHDPIATTILNEP----------TVIIERQIEFMNVFLGFEQANRYAIMDVNGNKIASMMERDFSITKAIMRQFYRLHRPFLVDVFDNWGNVIMTIKRPFSFINSHIKTIIPPSAYVDNGSDSTHYHDGKEGTTVGETIQNWHLWRRRYELFQKDGVEGSTFDQFGKIDAPFLSFDFPVTDADG-KIMASVDRNWVGLGREMFTDTGVYVVRFDSQRCFDNIYPTEMLSSQVLTLDQRAVLLANAVSIDFDYFSRHSRQTGGFLSFGGGYDE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * * .. . . : * :::.:::*:::.: *** *:: * : *: : * ... *: *** : ::*: . :: :.**: .. : * :* * * : :. . : ..:* : . :..: ::* * :* ***:. : :.* : * : :** :. . ** :*. ", "identical_positions": 36, "similar_positions": 72, "identity": "7.95%" }, { "cls_id": "homologset.agr.RGD:620522", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70615-1", "uniprot_id": "LMNB1_RAT", "id": "P70615-1", "name": "Lamin-B1", "aln": "---------------------MATATPVQQ-RAGSRASAPATPFSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSARGGMMESRMRIESLSSQLSNLQKDSRACLERIQELEDMLAKERDNSRRMLSDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRG------------------------KRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDT--SVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVKVVLKNSQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVPLE---EERFHQQGTPRASNKSCAIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14733-1", "uniprot_id": "LMNB1_MOUSE", "id": "P14733-1", "name": "Lamin-B1", "aln": "---------------------MATATPVQQQRAGSRASAPATPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKFKAEHDQLLLNYAKKESDLSGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLSAAKKQLADETLLKVDLENRCQSLTEDLEFRKNMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDMLAKERDNSRRMLSDREREMAEIRDQMQQQLSDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRG------------------------KRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDT--SVSYKYTSRYVLKAGQTVTVWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEEEPIGVAVE---EERFHQQGAPRASNKSCAIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20700-1", "uniprot_id": "LMNB1_HUMAN", "id": "P20700-1", "name": "Lamin-B1", "aln": "---------------------MATATPVPP-RMGSRAGGPTTPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKCKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDLLAKEKDNSRRMLTDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRG------------------------KRKRVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDT--SVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEE-AAGVVVE---EELFHQQGTPRASNRSCAIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QHC4-1", "uniprot_id": "F1QHC4_DANRE", "id": "F1QHC4-1", "name": "", "aln": "---------------------MASAACTPAGQQSLSRGTSSTPLSPARISRLQEKEELQQLNDRLAAYIDTVRSLESENSVLQIQIREREDVRNRELTGLRTLYETELADARKALDDTARERARLQIELGKIKSEQEQLQHTYAKKDADLTSSQNRLKDVEALLNAKEAALNTAVSERKTLENTLSDLQIRVQELEGGLISAKKQLSDETLLRVDLENRCQSLMEELEFRKNMFEEEIKDTRRRHETRLVEVDSGRQMEYEFKLAQALTDMRQQHDEQVKLYKEEMEQTYVSKLENIRLSSEMNSSSASMAREELRESTLRVESLAGQLANLQKEARAWQDRINELEGALSHEKDLSRRLLAEKEREIAEIRAKMQQQLDEYEQLLDVKLALDMEINAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRG------------------------KRKRVDVEESEASSSVSIAHSASATGNVSIDELDVDGKFIRLHNNSEQDQPMAGFQLTRTIGEV--TATYKFTAKYNLKAGQKVTIWASNAGISSNPPADLIWKNQPSWGTGENIKVALLSPAGEEVAVRSTVFKTAVEDEDDDEEEEKEAEVIE---EHFYHQQGDPRAAKRGCLIM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08928-1", "uniprot_id": "LMNB_DROME", "id": "P08928-1", "name": "Lamin", "aln": "MSSKSRRAGTATPQPGNTSTPRPPSAGPQPPPPSTHSQTASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITP---ATNTATVQSFSQSLRNST-----RATPSRR---TP----SAAVKRKRAVVDESEDHSVADYYVSASAKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPSSLVMKS-QKWVSADNTRTILLNSEGEAVANLDRIKRIVSQHTSSSRLSRRRSVTAVDGNEQLYHQQGDPQQSNEKCAIM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03427-1", "uniprot_id": "LMNA_DROME", "id": "Q03427-1", "name": "Lamin-C", "aln": "MSARR--------VTLNTRVSRASTSTPVGGASTSSRVGATSPTSPTRTSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRRTVIDESEDRTLSEYSVNAAAKGDLEIIEADVEGRFIKLHNKGTEEINLTGWQLTRIAGDE--ELAFKFSRGSKVLGGASVTIWSVDAGTAHDPPNNLVMK--KKWPVANSMRSVLANADKEDVASYDRVRANVSSHTSRHRSSGTPSTGFTLGSG-----AGSTGVRSLFSLLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:: .::* **:* ** ** **:.****** *** :*.**.*** * :: .:. ** :.:: ::* ** :*: **:**:::*: :*:: : *:::* ** : . :: . : * * : : .::*.:: .: . .*. : :*:* *** :***** *** *:* *:..:. :*:.::* :: . *:*. . :*: ** *:* ::* *:: *::: ::*:: * :::. : :: :. : : :::.* .:: :*:. **.:** * ::: : : * *: .:* :* :**.:*: *:*:*::**:** ** *** *** **:: . . * . : : **:*. ::*** : . .*:*.*:: * * * :*:*::* *.. :: : *::: * .: ::*: : . :*:*: :: : .** .*: * .* .:. : * .. * ** . : . . . . . . * . . . ::", "identical_positions": 139, "similar_positions": 199, "identity": "21.79%" }, { "cls_id": "homologset.agr.RGD:620523", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q498R2-1", "uniprot_id": "Q498R2_RAT", "id": "Q498R2-1", "name": "Transcription factor 21", "aln": "MSTGSLSDVEDLQEVEMLDCDSLKVDSNKEFGTSNESTEEGSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35437-1", "uniprot_id": "TCF21_MOUSE", "id": "O35437-1", "name": "Transcription factor 21", "aln": "MSTGSLSDVEDLQEVEMLDCDSLKVDSNKEFGTSNESTEEGSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPENDLKEVVTANRLCGTTAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43680-1", "uniprot_id": "TCF21_HUMAN", "id": "O43680-1", "name": "Transcription factor 21", "aln": "MSTGSLSDVEDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32PV5-1", "uniprot_id": "TCF21_DANRE", "id": "Q32PV5-1", "name": "Transcription factor 21", "aln": "MSTGSISDVDEFHESELLDG-LPKFGSGKDPGTSNESTEDSSNCEGASVSECTG--KRRKSANMRRSAPNGVAQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPENELKEMLNSTRLCGTTAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:***::::* *:*: *..*.*: *******:.****..* .: * :*:.* ::*. .**:****************************************************************************************.:***::.:.********", "identical_positions": 131, "similar_positions": 32, "identity": "73.18%" }, { "cls_id": "homologset.agr.RGD:620524", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TQ20-1", "uniprot_id": "DNJC2_RAT", "id": "Q7TQ20-1", "name": "DnaJ homolog subfamily C member 2", "aln": "-MLLLPSAAEGQGTAITHALTSASAVCQVEPVGRWFEAFVKRRNR-NASTSFQELEDKKELSEESED-------EELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKTMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKENFFQVFSPVFERNSRWSNKKNVPKLGDMNSSFEDVDAFYSFWYNFDSWREFSYLDEEEKEKAECRDERKWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEGKAKKEAEKRAKAEARRKEQEAKEKQRQAELEAVRLAKEKEEEEVRQQALLAKKEKEIQKKAIKKERQKLRNSCKNWNHFSDNEADRVKMMEEVEKLCDRLELASLQCLNEILASSTREVGKAALEKQIEEVNELMRKEKEEADARMRQASKNAEKSTGGSGSGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSS-SGVKRTAKDVIGKAKSLQKLDPHQ---KDDINKKAFDKFKK----------------------------------------EHGVAP-QADSAAPSERFEGPCIDS------IPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMRRYKELVEMVKAKKAAQEQVLNASRARK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54103-1", "uniprot_id": "DNJC2_MOUSE", "id": "P54103-1", "name": "DnaJ homolog subfamily C member 2", "aln": "-MLLLPSAAEGQGTAITHALTSASSVCQVEPVGRWFEAFVKRRNR-NASTSFQELEDKKELSEESED-------EELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYTATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFQVFSPVFERNSRWSNKKNVPKLGDMNSSFEDVDAFYSFWYNFDSWREFSYLDEEEKEKAECRDERKWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEARRKEQEAKEKQRQAELEAVRLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKSWNHFSDNEADRVKMMEEVEKLCDRLELASLQGLNEILASSTREVGKAALEKQIEEVNEQMRREKEEADARMRQASKNAEKSTGGSGSGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSS-SGVKRTAKDVISKAKSLQKLDPHQ---KDDINKKAFDKFKK----------------------------------------EHGVAS-QADSAAPSERFEGPCIDS------TPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMRRYKELVEMVKAKKAAQEQVLNASRARK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99543-1", "uniprot_id": "DNJC2_HUMAN", "id": "Q99543-1", "name": "DnaJ homolog subfamily C member 2", "aln": "-MLLLPSAADGRGTAITHALTSASTLCQVEPVGRWFEAFVKRRNR-NASASFQELEDKKELSEESED-------EELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFEVFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKTWNHFSDNEAERVKMMEEVEKLCDRLELASLQCLNETLTSCTKEVGKAALEKQIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSS-SGVKRTAKDVIGKAKSLQKLDPHQ---KDDINKKAFDKFKK----------------------------------------EHGVVP-QADNATPSERFEGPYTDF------TPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELVEMVKAKKAAQEQVLNASRAKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NWJ4-1", "uniprot_id": "DNJC2_DANRE", "id": "Q6NWJ4-1", "name": "DnaJ homolog subfamily C member 2", "aln": "---MLTEALEGQLTVVYNTVA-ASVQVQVEPVGRWFEAFLKRRNR-NVSASFQELEEEEELSEEEED-------EELQLEEYPMLKTLDPKDWKNQDHYAVLGLAHVRYKATQKQIKAAHKAMVLKHHPDKRKAAGEQIVEGDNDYFTCITKAIEILSDPVKRRAFDSVDPTFDNAVPTKAEGKENFFEVFAPVFERNARWSVKKHFPSLGTMESSFEDVDNFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRASRAQRKKEEMNRIRTLVDTAYNADPRIKKFKEEEKARKESEKKAKVEAKKREQEEKERARQQQEEAARLLKEQQEEAARQAAQQAKKEKEAQKKAIKKERQKLRMTCKSQNYFTDNEADSVRMMEEVEKLCDRLELISLQTLNEALSAGNKEQSKAALEKQVQEVNMQLQKEKD-AELQAQQAARGSEHSSAAGGQNNRGWSEEDLQLLIKAVNLFPAGTNARWEVIANYMNQHSS-SGVRRTAKDVINKAKTLQKLDPHQ---KDEINRKAFEKFKK----------------------------------------EHSAVPPTVDNAMPSERFDAVGADSN----AAAWTTEEQKLLEQALKTYPVSTAERWERISEAVPGRSKKDCMKRYKELVEMIKAKKAAQEQVAAKNKK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP77-1", "uniprot_id": "Q9VP77_DROME", "id": "Q9VP77-1", "name": "", "aln": "------MTSGTVATAVEVQLPLKVVRRKIERVG--FAYFAQRRQF-LAPGGVERSESDEKLEGVGEE-------VDIS-----YLKSLDPKEWKDQDHYAVLGLGKLRYEASEDDVRRAYRRMVLLHHPDKRKAKGEEVIQ-DDDYFTCITKAYEILGTSKPRRSFDSVDPEFDDSLPSQNDIDNDYFGVFNKFFTLNGRWSEKPHVPSFGQVDAKREEVERFYNFWYDFKSWREFSYLDEEDKEKGQDRDERRWIEKENRAARIKRKKEEMSRIRSLVDLAYNNDKRIQRFKQEEKDRKAAAKRAKMDAAQAQKAEADRAIR----EAALAKEKAEKAEQKRIEQIRIEREQQKKLLKKERKTLRDKVKDCKYYAKNDKDQLKHMEGTEKICETFNLAELQALNKAMESKGRESFVAALQTAEQKIAAEL-EEINQTQAKKLASSAATPKGVKEVKK-NELWSNENVQLLIKAVNLFPAGTAQRWDVIATFINQHSPDNTVLVNARDVLNKAKALQNTDHSKSSLKTQANDAAFASFEKSKKDVQTCKDITLGEETAQASKENLKQNGVDHKANNQSTKQNGTAPAPANPTAAPAPVPATNGSTGGGAASKTWTKEEQALLEQAIKTYPTTTPDRWDCIAACIPNRSKKDCLRRVKELVELVNSKKEAQAAVK-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32527-1", "uniprot_id": "ZUO1_YEAST", "id": "P32527-1", "name": "Zuotin", "aln": "MFSLPTLTSDITVEVNSSATKTPFVRRPVEPVGKFFLQHAQRTLRNHTWSEFERIEAEKNVKTVDESNVDPDELLFDTELADEDLLTHDARDWKTADLYAAMGLSKLRFRATESQIIKAHRKQVVKYHPDKQSAAGGSLDQ--DGFFKIIQKAFETLTDSNKRAQYDSCDFVADVPPPKKG-TDYDFYEAWGPVFEAEARFSKKTPIPSLGNKDSSKKEVEQFYAFWHRFDSWRTFEFLDEDVPDDSSNRDHKRYIERKNKAARDKKKTADNARLVKLVERAVSEDPRIKMFKEEEKKEKERRKWEREAGARAEAEAKAKAEA----EAKAKAESEAKANASAKADKKKAKEAAKAAKKKNKRAIRNSAKEADYFGDADK------------------------------------ATTIDEQVGLIVDSLNDEELVSTADKIKANAAGAK-----------------EVLKESAKTIVDSGKLPSSLLSYFV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :* ** * . :* . .:. * .:::. *. * : *.::** * **.:**.::*: *:: :: *:: *: :****:.* * : : :.:*. * ** * * . * ::* * * . *.: . ::: .: .* :.*:* * .*.:* ::. ::*: ** **: *.*** *.:***: :... **.:::**::*:*:* ::*. : *: .**: * . * **: **:* * .* * : . : : : . *. : . : :: * **::: :* . * .:: . : :::: : : * : : : ::* ::.: : . .::: :: ", "identical_positions": 85, "similar_positions": 139, "identity": "12.48%" }, { "cls_id": "homologset.agr.RGD:620525", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1P3-1", "uniprot_id": "MCL1_RAT", "id": "Q9Z1P3-1", "name": "Induced myeloid leukemia cell differentiation protein Mcl-1 homolog", "aln": "MFGLRRNAVIGLNLYCGGASLGAG--GGSPAGTRLAA--EEAKARRE-GGGEA--------------ALLPGARVVARPPPVGAEDPDVTASAERRLLKSPGLLAVPPEEMAAS-AAAIMSPEEELDGCEPEVLSKRPAVLPLLERVSEAAKSSGADGSLPSTPPPPEEEDDELYRQSLEIISRYLREQATGSKDAKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSFSRVMTHVFKDGVTNWGRIVTLISFGAFVAKHLKSINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVQDLEGGIRNVLLAFAGVAGVGAGLAYLIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97287-1", "uniprot_id": "MCL1_MOUSE", "id": "P97287-1", "name": "Induced myeloid leukemia cell differentiation protein Mcl-1 homolog", "aln": "MFGLRRNAVIGLNLYCGGASLGAG--GGSPAGARLVA--EEAKARRE-GGGEA--------------ALLPGARVVARPPPVGAEDPDVTASAERRLHKSPGLLAVPPEEMAASAAAAIVSPEEELDGCEPEAIGKRPAVLPLLERVSEAAKSSGADGSLPSTPPPPEEEEDDLYRQSLEIISRYLREQATGSKDSKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEGDVKSFSRVMVHVFKDGVTNWGRIVTLISFGAFVAKHLKSVNQESFIEPLAETITDVLVRTKRDWLVKQRGWDGFVEFFHVQDLEGGIRNVLLAFAGVAGVGAGLAYLIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07820-1", "uniprot_id": "MCL1_HUMAN", "id": "Q07820-1", "name": "Induced myeloid leukemia cell differentiation protein Mcl-1", "aln": "MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:**************.**** *.: .* ** * :**.**** ***** :* *.:* ******:*** *****:. * * :* *.* *** *. * **:******** *** :.********** *.*:.:.:.:**********.***:*:*******************:**:**:*.:**:.*:********************************.****:**** ***.************************::**** ******:****************************:****************************", "identical_positions": 264, "similar_positions": 45, "identity": "75.43%" }, { "cls_id": "homologset.agr.RGD:620526", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2VIQ3-1", "uniprot_id": "KIF4B_HUMAN", "id": "Q2VIQ3-1", "name": "Chromosome-associated kinesin KIF4B", "aln": "MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLS-FVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEIDKKS-DFEFTLKVSYLEIYNEEILDLLCPSREKA-QINIREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQ----------AHGGTLPGSINAEPSEN--------LQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACTAAAIDTAVEEEAQVETSP----ETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQ-----SHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQQLLQENEIIKQKLILLQVASRQK-HLPNDTLLSPDSSFEYIPPK----PKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDGDSDEGDDEEWKPTKLVKVSRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCSCDPTKCRNRQQGKDSLGTVEQTQDSEGSFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDMEQVLSKKTAPAPSPFDLPESKHGATEYQQNKPPGKKKKRALASNTSFFSGCSPIEEEAH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O95239-1", "uniprot_id": "KIF4A_HUMAN", "id": "O95239-1", "name": "Chromosome-associated kinesin KIF4A", "aln": "MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLS-FVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDKKS-DFEFTLKVSYLEIYNEEILDLLCPSREKA-QINIREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQ----------AHGGTLPGSITVEPSEN--------LQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSP----ETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQ-----SRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQK-HLPKDTLLSPDSSFEYVPPK----PKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGD--DDEGDDEEWKPTKLVKVSRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCCCDPTKCRNRQQGKDSLGTVERTQDSEGSFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDVEQVLSKKTPPAPSPFDLPELKHVATEYQENKAPGKKKKRALASNTSFFSGCSPIEEEAH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9PSJ3-1", "uniprot_id": "E9PSJ3_RAT", "id": "E9PSJ3-1", "name": "", "aln": "MKEEVKGIPVRVALRCRPLVSKEINEGCQTCLS-FVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQEHDSAIGVIPRVIQLLFKEINKKT-DFEFTLKVSYLEIYNEEILDLLCSSREKASQINIREDPKEGIKIVGLTEKTVLVASDTVSCLEQGNNCRTVASTAMNSQSSRSHAIFTISIEQRKKNDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGNFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIINIDPQAAELNHLKQQVQQLQVLLLQ----------AHGGTLPGNINVKPSEN--------LQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKVDLQKLAETLEDQEVKENIEIICNLQQAIARLSDEAVACMTATIDTAGEVDTQEQSSP----DTSRSSDVFSTQHALRQAQMSKELIELNKELALKEALAKKMTQNDNQLQPIQFQYQDNIKNLELEVLSLQKEKEELVLELQTAKKDVNQAKLSERRRKRLQELEGQIAELKKKLHEQSKLLKLKETTELTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQQKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQKEVAEKRKETQ-----SRGMEGTAARMKSWLGNEIEVMVSTEEAKRHLNDLLEERKILAQDVAQLKEKRESGENPPPKLRRRTFSRDEVHGQDSGAEDSISKQIESLESELELRSAQIADLQQKLLDAESEDQPKQRWENIATILEAKCAIKYLVGELVSSKIQVSKLESGLSQSKASCIEVQKMLFEEQNHFAKIETELKEELVRVEQQHQEKVLYLLSQLQQCQVTEKQLEESVSEKEQQLLSTLKCQEEELRKMQEVCEQNQQLLQENSAIKQKLNLLQVVSKEKPHLVRNILQSPDSSFEYIPPK----PKPFRIKEKCPEKSFAIEDLQYYSETSVAEEENEDSD----DHADEEWIPTKLVKVSKKNIQGCSCKGWCGNKQCGCRKQKSDCNGACSCDPTKCRNRHHSQDNSDVIELNQDSENSFKLEDPTEVTSGLSFFNPVCTTPSSKILKEMCDADQVLLRQPDFASS-SDHLELKPIASETQENKAMGKKKKRALASNTSFFSGCSPIQEESH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33174-1", "uniprot_id": "KIF4_MOUSE", "id": "P33174-1", "name": "Chromosome-associated kinesin KIF4", "aln": "MKEEVKGIPVRVALRCRPLVSKEIKEGCQTCLS-FVPGEPQVVVGNDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQEHDSAIGVIPRVIQLLFKEINKKS-DFEFTLKVSYLEIYNEEILDLLCSSREKATQINIREDPKEGIKIVGLTEKTVLVASDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKNDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLREGININRGLLCLGNVISALGDDKKGNFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIINIDPQAAELNHLKQQVQQLQILLLQ----------AHGGTLPGDINVEPSEN--------LQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRRHAACKVDLQKLVETLEDQELKENIEIICNLQQVIAQLSDEAAACMTATIDTAGEADTQVQSSP----DTSRSSDVFSTQHALRQAQMSKELIELNKALALKEALAKKMTQNDNQLQPIQFQYQDNIKNLESEVLSLQREKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLQEQSKLLKLKESTEHTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQQKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQKEVAEKRKETQ-----SRGMESTAARMKNWLGNEIEVMVSTEEAKRHLNGLLEERKILAQDVAQLKEKRESGENPPLKLRRRTFSYDEIHGQDSGAEDSIAKQIESLETELELRSAQIADLQQKLLDAESEDRPKQRWESIATILEAKCAIKYLVGELVSSKILVSKLESSLNQSKASCIDVQKMLFEEQNHFAKIETELKEELVKVEQQHQEKVLYLLSQLQQSQMTEKQLEESVSEKEQQLLSTLKCQEEELRKMQEVCEQNQQLLQENSAIKQKLTLLQVASKQKPHLTRNIFQSPDSSFEYIPPK----PKPCRIKEKCLEQSFAVEGLQYYSEPSVAEQDNEDSD----DHADEEWIPTKLVKVSKKSIQGCSCKGWCGNKQCGCRKQKSDCNVSCSCDPTKCRNRHQNQDNSDAIELNQDSENSFKLEDPTEVTSGLSFFHPICATPSSKILKEMCDADQVQLKQPVFVSS-SDHPELKSIASESQENKAIGKKKKRALASNTSFFSGCSPIQEESH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9XZ29-1", "uniprot_id": "Q9XZ29_DROME", "id": "Q9XZ29-1", "name": "", "aln": "-MSSEDPSCVAVALRVRPLVQSELDRGCRIAVERSADGAPQVTVNRNESYTYNYVFDIDDSQKDLFETCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNG--VLDDHVGVIPRAVHDIFTAIAEMQSEFRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIR-EVKNRIIMPGLTELVVTSAQQVTDHLIRGSAGRAVAATAMNETSSRSHAIFTLTLVATKLDGKQSVTTSRFNLVDLAGSERCSKTLASGDRFKEGVNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADYNVAETLSTLRYADRALQIKNKPVVNLDPHAAEVNMLKDVIQKLRVELLSGGKMSSSLISAVGAAGLGAIPCEESLAGSMANAAEIQRLKEQVRTLQDRNRKLQQELHQSLLDLTEKEMRAHIAEQAHDKLRSHVSELKNKLDQREQAQFGNENTNGDNEMRDFSLLVNRVHVELQRTQEELESQGHESRQRLSSRSHTEGGESGGDEVHEMLHSHSEEYTNKQMNFAGELRNINRQLDLKQELHERIMRNFSRLD--SDDEDVKLRLCNQKIDDLEAERRDLMDQLRNIKSKDISAKLAEERRKRLQLLEQEISDLRRKLITQANLLKIRDKEREKIQNLSTEIRTMKESKVKLIRAMRGESEKFRQWKMVREKELTQLKSKDRKMQSEIVRQQTLHSKQRQVLKRKCEEALAANKRLKDALERQASAQAQRHKYKDNGGSAAGSSNANAKTDSWVDRELEIILSLIDAEHSLEQLMEDRAVINNHYHLLQQEKTS---------------------DPAEAAEQARILASLEEELEMRNAQISDLQQKVCPTDLDSRIRSLAEGVQSLGESRTVSKQLLKTLVQ---QRRLQASSLNEQRTTLDELRAQLLDAQ---------------QQEDAASKRLRLLQSQHEEQMLAQQRAYEEKVSVLIRTANQRWAEARSPAEDQQRNQILEELLSSREALQQELDKLRAKNKSKSKAVKSEPQDLDDSFQIVDGNETVVLSDVSDDPDWVPSTSKSKRIQSDSRNVISPPEKQDANVTSLGNSSIQSLNSTSATEDGKRCKGCKCRTKCTTKRCGCLSGNNACSETCVCK-SNCRNPLNLKDHASQCGDGDGQKDETEDADKSDDD-GDDEPQTSKENAVKFVTPEAPGKVVASPKQTLQEPKAAATPLMNSNVVEDINGPKLAKMSGLAFDTPKRKFF----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . * **** **** .*:..**: .:. . * .**.*. ::*:**::*** .*:::*:..* . :* :::***.*:************:** *:.. : :*:***.:: :*. * : :*.*::. *::*:*:*:: **:... .. ::** : *: * : **** .* * :... * :*. *:**:****. *********::: * ..*:. *:::********* .** *.***::**:***:***.*****.***..: ..::***:*************** *********** *: ***.******** :*****::*:**::**:* **: :*:*:: **. * *.: * * : * :* * *: ::* :.*.**.: * :: : :: * ::**.::*:.:::.**:.: : : * *. :.:: .:..:: * : : ::* . . :: : . :. . . .: ::: :* ::: *: ::*. * **: * .:: :* .:*: . : : ::: : :: .*: *:.:*: :*:. *.. .***:*.*:* ** ** :*::*::** *::***:::. . .:.:*. ** **:.:*:*:* *: ::******* ::**: ***.:*** * *::: : ..** .**:** *** **********::* .. :*:: : : * .. *: .*:..*:*:::* :*:: *: *:*:* :: :. *:::: * :: : *** *:*:*.***:*****: :: :.: :. *.: :: *:: . * *: **. ..* :.::: ::: *:: : : *: .::: * ** :: ::::: :. . : . .: .. : :: : ::** ... ::*:* *:. .:.* : .. . *.**: : : . . . .: : :: *. : :. *.: . : :. .. . * :**.*: * .*:*** . :. *. * *. ::*** : :* . :..:.. : * :: * . :. .. . : * . . ::. .. : . * :. .* . *: : . * ", "identical_positions": 354, "similar_positions": 447, "identity": "27.9%" }, { "cls_id": "homologset.agr.RGD:620527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXU2-1", "uniprot_id": "SURF1_RAT", "id": "Q9QXU2-1", "name": "Surfeit locus protein 1", "aln": "---MAAVMALTVLRSRITRWPQWACAGPAPFCAVRRSVFGFSVRSGMVCRPHRCCSSTAETAAAKAED-DSFLQWFLLFIPATAFGLGTWQVQRRKWKLKLIAELESRVMAEPIPLPA--DPMELKNLEYRPVKVRGHFDHSKELYIMPRTMVDPVREARDAGRLSS--TESGAYVVTPFHCSDLGVTILVNRGFVPRKKVNPETRQQGQV----LGEVDLVGIVRLTENRKPFVPE-NNPERSLWYYRDLDAMAKRTGTDPIFIDADFN-------------------------------------------------------------------STTPGGPIGGQTRVTLRNEHMQYIITWYGLCAATSYLWFRKFVRRTPGV-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09925-1", "uniprot_id": "SURF1_MOUSE", "id": "P09925-1", "name": "Surfeit locus protein 1", "aln": "---MAAVMALAVLPRRMTRWSQWAYAGRAQFCAVRRSVFGFSVRSGMVCRPRRCCSSTAETAAAKAED-DSFLQWFLLLIPATAFGLGTWQVQRRKWKLKLIAELESRVMAEPIPLPA--DPMELKNLEYRPVKVRGHFDHSKELYIMPRTMVDPVREARDAGRLSS--TESGAHVVTPFHCSDLGVTILVNRGFVPRKKVNPETRQKGQV----LGEVDLVGIVRLTENRKPFVPE-NSPERNHWYYRDLEAMAKITGADPIFIDADFH-------------------------------------------------------------------STAPGGPIGGQTRVTLRNEHMQYILTWYGLCAATSYLWFQKFVRRTPIM-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15526-1", "uniprot_id": "SURF1_HUMAN", "id": "Q15526-1", "name": "Surfeit locus protein 1", "aln": "---MAAVAALQLGLR-------AAGLGRAPASAAWRSVLRVSPRPGVAWRPSRCGSSAAEASATKAED-DSFLQWVLLLIPVTAFGLGTWQVQRRKWKLNLIAELESRVLAEPVPLPA--DPMELKNLEYRPVKVRGCFDHSKELYMMPRTMVDPVREAREGGLISSS-TQSGAYVVTPFHCTDLGVTILVNRGFVPRKKVNPETRQKGQI----EGEVDLIGMVRLTETRQPFVPE-NNPERNHWHYRDLEAMARITGAEPIFIDANFQ-------------------------------------------------------------------STVPGGPIGGQTRVTLRNEHLQYIVTWYGLSAATSYLWFKKFLRGTPGV-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9U4F3-1", "uniprot_id": "SURF1_DROME", "id": "Q9U4F3-1", "name": "SURF1-like protein", "aln": "MIRLGNQMCRQVAFN-------IQTVFRNPGTANNPRLITRKMTQ--QRPPVNWTTSIPNQAAKDKEK-IAPLGWFLLLIPATTFGLGCWQVKRKIWKEQLIKDLNKQLSTAPVALPD--DLTDLAQMEYRLVKIRGRFLHDKEMRLGPRSLIRPDGVETQGGLFSQRDSGNGYLIVTPFQLADRDDIVLVNRGWVSRKQVEPETRPLGQQ----QAEVELTAVVRKGEARPQFTPD-HKG--NVYLYRDLARMCAATGAAPVFLDAVYDP------------------------------------------------------------------QTAAHAPIGGQTRVTLRNDHLSYLVTWFSLSAATSFLWYRQIVKRIPF--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53266-1", "uniprot_id": "SHY1_YEAST", "id": "P53266-1", "name": "Cytochrome oxidase assembly protein SHY1", "aln": "MSLLGARSTYRWFSIAASIPTKNAIGKSTYLLASRNQQYRGIITSTVDWKPIKTGKSPNDDSRRERSFGKKIVLGLMFAMPIISFYLGTWQVRRLKWKTKLIAACETKLTYEPIPLPKSFTPDMCEDWEYRKVILTGHFLHNEEMFVGPRKKNG----------------EKGYFLFTPFIRDDTGEKVLIERGWISEEKVAPDSRNLHHLSLPQEEHLKVVCLVRPPKKRGSLQWAKKDPNSRLWQVPDIYDMARSSGCTPIQFQALYDMKDHPIIEEHTRNEASQNNSTSSLWKFWKREPTTAVNGTQAVDNNTSKPRSRQEMPTDQTIEFDERQFIKAGVPIGRKPTIDLKNNHLQYLVTWYGLSFLSTIFLIVALRKAKRGGVVSQDQLMKEKLKHSRKYM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * * . .* : : . . : .:: :* :* ** ***:* ** :** :.:: *:.** : *** * : * * *.:*: : **. .* :.*** * . :*::**::..::* *::* : .:.: :** : * : :. : *: *. :* *: ::* :. . *** :. : *:*:*:.*::**:.*. :: : : : ", "identical_positions": 57, "similar_positions": 81, "identity": "14.07%" }, { "cls_id": "homologset.agr.RGD:620528", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0U5-1", "uniprot_id": "AOXA_RAT", "id": "Q9Z0U5-1", "name": "Aldehyde oxidase 1", "aln": "MD-PPQLLFYVNGQKVVENNVDPEMMLLPYLRKNLRLTGTKYGCGGGGCGACTVMISRYNPSTKSIRHHPVNACLTPICSLYGTAVTTVEGIGNTRTRLHPVQERIAKCHSTQCGFCTPGMVMSMYALLRNHPEPSLDQLTDALGGNLCRCTGYRPIIDACKTFCRASGCCESKENGVCCLDQGINGSAEFQEGDETSPELFSEKEFQPLDPTQELIFPPELMRIAEKQPPKTRVFYSNRMTWISPVTLEELVEAKFKYPGAPIVMGYTSVGPEVKFKGVFHPIIISPDRIEELSIINQTGDGLTLGAGLSLDQVKDILTDVVQKLPEETTQTYRALLKHLRTLAGSQIRNMASLGGHIVSRHLDSDLNPLLAVGNCTLNLLS----KDGKRQIPLSEQFLRKCPDSDLKPQEVLVSVNIPCSRKWEFVSAFRQAQRQQNALAIVNSGMRVLFREGGGVIKELSILYGGVGPTTIGAKNSCQKLIGRPWNEEMLDTACRLVLDEVTLAGSAPGGKVEFKRTLIISFLFKFYLEVLQGLKREDPGHYPSLTNNYESALEDLHSKHHWRTLTHQNVDSMQLPQDPIGRPIMHLSGIKHATGEAIYCDDMPAVDRELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITADHLQDAT-TFG----TETLLATDKVHCVGQLVCAVIADSETRAKQAAKHVKVVYRDLEPLILTIEEAIQHKSFFESE-RKLECGNVDEAFKIADQILEGEIHIGGQEHFYMETQSMLVVPKGEDGEIDIYVSTQFPKHIQDIVAATLKLSVNKVMCHVRRVGGAFGGKVGKTSIMAAITAFAASKHGRAVRCTLERGEDMLITGGRHPYLGKYKVGFMRDGRIVALDVEHYCNGGSSLDESLWVIEMGLLKMDNAYKFPNLRCRGWACRTNLPSHTALRGFGFPQAGLVTEACVTEVAIRCGLSPEQVRTINMYKQIDNTHYKQEFSAKTLFECWRECMAKCSYSERKTAVGKFNAENSWKKRGMAVIPLKFPVGVGSVAMGQAAALVHIYLDGSALVSHGGIEMGQGVHTKMIQVVSRELKMPMSSVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIISKNPQGTWKDWAQTAFDQSVSLSAVGYFRGYESNINWEKGE-GHPFEYFVYGAACSEVEIDCLTGDHKNIRTDIVMDVGHSINPALDIGQVEGAFIQGMGLYTIEELSYSPQGILYSRGPNQYKIPAICDIPTEMHISFLPPSEHSNTLYSSKGLGESGVFLGCSVFFAIHDAVRAARQERGISGPWKLTSPLTPEKIRMACEDKFTKMIPRDEPGSYVPWNIPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54754-1", "uniprot_id": "AOXA_MOUSE", "id": "O54754-1", "name": "Aldehyde oxidase 1", "aln": "MD-PIQLLFYVNGQKVVEKNVDPEMMLLPYLRKNLRLTGTKYGCGGGGCGACTVMISRYNPSTKAIRHHPVNACLTPICSLHGTAVTTVEGLGNTRTRLHPIQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTFCKASACCQSKENGVCCLDQEINGLAESQEEDKTSPELFSEEEFLPLDPTQELIFPPELMRIAEKQPPKTRVFYGERVTWISPVTLKELVEAKFKYPQAPIVMGYTSVGPEVKFKGVFHPIIISPDRIEELGVISQARDGLTLGAGLSLDQVKDILADIVQKLPEEKTQTYRALLKHLRTLAGSQIRNMASLGGHIVSRHLDSDLNPLLAVGNCTLNLLS----KDGERRIPLSEEFLRKCPEADLKPQEVLVSVNIPWSRKWEFVSAFRQAQRQQNALAIVNSGMRVLFREGGGVIEELSILYGGVGSTIISAKNSCQRLIGRPWNEGMLDTRCRLVLDEVTLAASAPGGKVEFKRTLIISFLFKFYLEVSQGLKREDPGHSPSLAGNHESALDDLHSKHPWRTLTHQNVDPAQLPQDPIGRPIMHLSGIKHATGEAIYCDDMPAVDRELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITADHLQEAN-TFG----TETFLATDEVHCVGHLVCAVIADSETRAKQAAKQVKVVYQDLAPLILTIEEAIQHKSFFKSE-RKLECGNVDEAFKIVDQILEGEIHIGGQEHFYMETQSMLVVPKGEDGEIDIYVSTQFPKYIQDIVAATLKLSANKVMCHVRRVGGAFGGKVGKTSILAAITAFAASKHGRAVRCILERGEDMLITGGRHPYLGKYKAGFMNEGRILALDVEHYCNGGCSLDESLWVIEMGLLKLDNAYKFPNLRCRGWACRTNLPSNTALRGFGFPQAGLVTEACITEVAIKCGLSPEQVRTINMYKHVDTTHYKQEFSAKALSECWRECMAKCSYFERKAAIGKFNAENSWKKRGMAVIPLKFPVGIGSVAMGQAAALVHIYLDGSALVSHGGIEMGQGVHTKMIQVVSRELRMPMSSVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIISKNPQGTWKDWAQTAFDQSISLSAVGYFRGYESNIDWEKGE-GHPFEYFVFGAACSEVEINCLTGDHKNIRTNIVMDVGHSINPALDIGQVEGAFIQGMGLYTIEELSYSPQGTLYSRGPNQYKIPAICDIPTEMHISFLPPSEHSNTLYSSKGLGESGVFLGCSVFFAIHDAVKAARQERGISGPWKLNSPLTPEKIRMACEDKFTKMIPRDEPGSYVPCNIPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06278-1", "uniprot_id": "AOXA_HUMAN", "id": "Q06278-1", "name": "Aldehyde oxidase", "aln": "MDRASELLFYVNGRKVIEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISRYNPITKRIRHHPANACLIPICSLYGAAVTTVEGIGSTHTRIHPVQERIAKCHGTQCGFCTPGMVMSIYTLLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTFCKTSGCCQSKENGVCCLDQGINGLPEFEEGSKTSPKLFAEEEFLPLDPTQELIFPPELMIMAEKQSQRTRVFGSERMMWFSPVTLKELLEFKFKYPQAPVIMGNTSVGPEVKFKGVFHPVIISPDRIEELSVVNHAYNGLTLGAGLSLAQVKDILADVVQKLPEEKTQMYHALLKHLGTLAGSQIRNMASLGGHIISRHPDSDLNPILAVGNCTLNLLS----KEGKRQIPLNEQFLSKCPNADLKPQEILVSVNIPYSRKWEFVSAFRQAQRQENALAIVNSGMRVFFGEGDGIIRELCISYGGVGPATICAKNSCQKLIGRHWNEQMLDIACRLILNEVSLLGSAPGGKVEFKRTLIISFLFKFYLEVSQILKKMDPVHYPSLADKYESALEDLHSKHHCSTLKYQNIGPKQHPEDPIGHPIMHLSGVKHATGEAIYCDDMPLVDQELFLTFVTSSRAHAKIVSIDLSEALSMPGVVDIMTAEHLSDVN-SFCFFTEAEKFLATDKVFCVGQLVCAVLADSEVQAKRAAKRVKIVYQDLEPLILTIEESIQHNSSFKPE-RKLEYGNVDEAFKVVDQILEGEIHMGGQEHFYMETQSMLVVPKGEDQEMDVYVSTQFPKYIQDIVASTLKLPANKVMCHVRRVGGAFGGKVLKTGIIAAVTAFAANKHGRAVRCVLERGEDMLITGGRHPYLGKYKAGFMNDGRILALDMEHYSNAGASLDESLFVIEMGLLKMDNAYKFPNLRCRGWACRTNLPSNTAFRGFGFPQAALITESCITEVAAKCGLSPEKVRIINMYKEIDQTPYKQEINAKNLIQCWRECMAMSSYSLRKVAVEKFNAENYWKKKGLAMVPLKFPVGLGSRAAGQAAALVHIYLDGSVLVTHGGIEMGQGVHTKMIQVVSRELRMPMSNVHLRGTSTETVPNANISGGSVVADLNGLAVKDACQTLLKRLEPIISKNPKGTWKDWAQTAFDESINLSAVGYFRGYESDMNWEKGE-GQPFEYFVYGAACSEVEIDCLTGDHKNIRTDIVMDVGCSINPAIDIGQIEGAFIQGMGLYTIEELNYSPQGILHTRGPDQYKIPAICDMPTELHIALLPPSQNSNTLYSSKGLGESGVFLGCSVFFAIHDAVSAARQERGLHGPLTLNSPLTPEKIRMACEDKFTKMIPRDEPGSYVPWNVPI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10351-1", "uniprot_id": "XDH_DROME", "id": "P10351-1", "name": "Xanthine dehydrogenase", "aln": "MS-NSVLVFFVNGKKVTEVSPDPECTLLTFLREKLRLCGTKLGCAEGGCGACTVMVSRLDRRANKIRHLAVNACLTPVCSMHGCAVTTVEGIGSTKTRLHPVQERLAKAHGSQCGFCTPGIVMSMYALLRNAEQPSMRDLEVAFQGNLCRCTGYRPILEGYKTFTKEFACGMGEK---CCKVSGKG----CGTDAETDDKLFERSEFQPLDPSQEPIFPPELQ-LSDAFDSQSLIFSSDRVTWYRPTNLEELLQLKAKHPAAKLVVGNTEVGVEVKFKHFLYPHLINPTQVKELLEIKENQDGIYFGAAVSLMEIDALLRQRIEQLPESETRLFQCTVDMLHYFAGKQIRNVACLGGNIMTGSPISDMNPVLSAAGAQLEVASFVDGKLQKRSVHMGTGFFTGYRRNVIEAHEVLLGIHFRKTTPDQYIVAFKQARRRDDDIAIVNAAINVRFEEKSNIVAEISMAFGGMAPTTVLAPRTSQLMVGQEWSHQLVERVAESLCTELPLAASAPGGMIAYRRALVVSLFFKAYLAISLKLSKSGITSSDALPSEERSGAETFHTPVLKSAQLFERVCSDQPICDPIGRPKVHAAALKQATGEAIYTDDIPRMDGEVYLAFVLSTKPRAKITKLDASEALALDGVHQFFCYKDLTEHENEVGPVFHDEHVFAAGEVHCYGQIVGAIAADNKALAQRAARLVKVEYEELSPVIVTIEQAIEHKSYFPDYPRFVTKGNVEEALAQADHTFEGTCRMGGQEHFYLETHAALAVPRDSD-ELELFCSTQHPSEVQKLVAHVTALPAHRVVCRAKRLGGGFGGKESRGISVALPVALAAYRMGRPVRCMLDRDEDMLITGTRHPFLFKYKVGFTKEGLITACDIECYNNAGWSMDLSFSVLERAMFHFENCYRIPNVRVGGWVCKTNLPSNTAFRGFGGPQGMYAGEHIIRDVARIVGRDVVDVMRLNFYKTGDYTHYHQQLEHFPIERCLEDCLKQSRYDEKRQEIARFNRENRWRKRGMAVVPTKYGIAFGVMHLNQAGSLINIYGDGSVLLSHGGVEIGQGLNTKMIQCAARALGIPSELIHISETATDKVPNTSPTAASVGSDLNGMAVLDACEKLNKRLAPIKEALPGGTWKEWINKAYFDRVSLSATGFYAMPGIGYHPETNPNARTYSYYTNGVGVTVVEIDCLTGDHQVLSTDIVMDIGSSLNPAIDIGQIEGAFMQGYGLFTLEELMYSPQGMLYSRGPGMYKLPGFADIPGEFNVSLLTGAPNPRAVYSSKAVGEPPLFIGSSAFFAIKEAIAAAREDQGLSGDFPLEAPSTSARIRIACQDKFTELLEIPEPGSFTPWNIVP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *:*:***:** * . *** **.:**::*** *** **. *********:** : :: *** ..**** *:**::* *******:*.*:**:**:***:**.*.:********:***:*:**** :*:: :* *: ************::. *** : .* .:: ** . . :*. :** ..** ****:** ****** ::: :: :* .:*: * *..*:**:: * *:* * :::* *.** ***** .::* :*.* :::** :.. :*: :**.:** ::. :* : :::***. *: ::. :. * :**.****:*.***:*:: **:**:*:.... *:: * * :* : :. *: ::.:*:*:.::: : ::: **:**:*::: :****:.:.* * * ..:: *:.: :**:..: : * .:.* ::*: *.. ::: .. : *:.* .***** : ::*:*::*::** ** : *.: . :*..: .*. : :*: : .:.: . * ****:* :* :.:*:******* **:* :* *::*:** *::.:***..:* ****:: ** ::: ..* : . * .:*:.:*.* *::* *: **.:. *::**: **: *.:* *:*:***::*:*:* * * : ***:**: .*: :** ::*******:**:: *.**:..* *:::: ***.*. :*.:** . *..::*:*:.:*:**.**** : :* .*:** : **.*** *:*.******* ***:* ***.** .:* * * *:* * *.* *:* *: *:* .:::::*.*::**:* **.*:*****:**:**** **. * : :** * . .* :*:** * * *:*::. : .* .:*: . * :: : :** ** *:*:*:*::* *: :..* .**.:*::** ***.*::***:*:***::***** .:* * :* . :*: *:*:.***:. :..** :****:** ***:.* *** ** . * ****:* :.*: : :.***.*:: . . *.. .:.:.*:. *.. : ***:******: : *:****:* *:***:****:****:** **:*:*** ***** *::***. **:*.:.*:* *:::::*. : :..::****.:**. :*:*.*.****::*: ***:::*: * * :* *. :**:**:****::: ****:.* *: ", "identical_positions": 550, "similar_positions": 462, "identity": "40.89%" }, { "cls_id": "homologset.agr.RGD:620529", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0U1-1", "uniprot_id": "IP6K2_RAT", "id": "Q9R0U1-1", "name": "Inositol hexakisphosphate kinase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPAFRTMDVEPRTKG----------------------------------------------ILLEPFVHQVGGHSCVLRFNETTLCKPLVPR-----------EHQFYETLPAEMRRFTPQYK-----------------------GVVSVRFEEDEDRNLCLIAYP--------------------LKGDHGPVDIVDNSDCEPKSK------LLRWT-NKKHHVL-------------------------------------------------------------------------------------ETEKSPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYSVE----------KKGTVSSQLKHYN----------------------------------------------PWSMKCHQQQLQRMKEN----------------------------------------------AKHRNQYKFILLENLTCRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVCGMQVYQAGTGQLMFMNKYHGRKLSV-QGFKEALFQFFHNGRYLR--RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKE--------------WPEVTLDS---------------DAEDLEDLSEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SADESAGAYAYKPLG-------------------------------------------------------------------------------------------------------------------------------------------------------------ASSVDVRMIDFAHTTCRLYG-------EDSVVHEGQDAGYIFGLQSLIDIVTEISEESGE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80V72-1", "uniprot_id": "IP6K2_MOUSE", "id": "Q80V72-1", "name": "Inositol hexakisphosphate kinase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPAFRTMDVEPRTKG----------------------------------------------ILLEPFVHQVGGHSCVLRFNETTLCKPLVPR-----------EHQFYETLPAEMRRFTPQYKAVLIFVRCADEFGASGNIETKEQGVVSVRFEEDEDRNLCLIAYP--------------------LKGDHGTVDIVDNSDCEPKSK------LLRWT-NKKHHAL-------------------------------------------------------------------------------------ETEKNPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYSVE----------KKGNVSSQLKHYN----------------------------------------------PWSMKCHQQQLQRMKEN----------------------------------------------AKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVCGMQVYQAGTGQLMFMNKYHGRKLSV-QGFKEALFQFFHNGRYLR--RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKE--------------WPEVTLDS---------------DAEDLEDLSEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SADESAGAYAYKPIG-------------------------------------------------------------------------------------------------------------------------------------------------------------ASSVDVRMIDFAHTTCRLYG-------EDSVVHEGQDAGYIFGLQSLIDIVTEISEESGE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHH9-1", "uniprot_id": "IP6K2_HUMAN", "id": "Q9UHH9-1", "name": "Inositol hexakisphosphate kinase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPAFRAMDVEPRAKG----------------------------------------------VLLEPFVHQVGGHSCVLRFNETTLCKPLVPR-----------EHQFYETLPAEMRKFTPQYK-----------------------GVVSVRFEEDEDRNLCLIAYP--------------------LKGDHGIVDIVDNSDCEPKSK------LLRWTTNKKHHVL-------------------------------------------------------------------------------------ETEKTPKDWVRQHRKEEKMKSHKLEEEFEWLKKSEVLYYTVE----------KKGNISSQLKHYN----------------------------------------------PWSMKCHQQQLQRMKEN----------------------------------------------AKHRNQYKFILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKLSV-QGFKEALFQFFHNGRYLR--RELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKE--------------RPEVVLDS---------------DAEDLEDLSEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SADESAGAYAYKPIG-------------------------------------------------------------------------------------------------------------------------------------------------------------ASSVDVRMIDFAHTTCRLYG-------EDTVVHEGQDAGYIFGLQSLIDIVTEISEESGE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2E9-1", "uniprot_id": "Q9W2E9_DROME", "id": "Q9W2E9-1", "name": "Kinase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVYFLGDWGMGDSDLSSYQQH----------------------------------------------VPNIQQPRRIHGHDLLLQQQQQQLPQQQQQQQQQQQQ----QQQEFVAQISSSLSQVQAQLQFASGSSFLQQGSSPSPSQQQHG-PVSSSSLVTANLQQLSVSSSN--------------------ASSSSSNNNSASGCNTPTKPQKQKPLLLPEAAASTATAVG-------------------------------------------------------------------------------------KSSKNPQLSKDLLDNEDEVALHPLSNQVGGHTRLLLLNQSTV----------IKPLNLRELDFYQNIPQDILKFVPKYKGVMQATTMGGAKLDKRYSPSFRDDAAAVPVRKMSASKRKRDEVLRMKVHKNGQAAEVIKS--------------------------------ISQLDNTNKQYFLMLENITSQFRNPCILDLKMGTRQHGDDASAEKRSKQMAKCAASTSGSLGVRLCGMQTYLADLEQYAKRDKYWGRELNE-GGFKTALHDFFHNGYRLR--IRVIRKILQRLLQLRRVIEKQSSYRFYSCSLLIVYEGFEENPMAPPPSMSQDEWPEAPRSATVPGTVFDYHPENSIDEDDLEDDDEAGNEAGDELEAHDTDDDLHLVAADSGNASATNSSTGGDACNYDADASNDSNSLLNLATRRHLHKRGFAEAAARGVKQTASHNTTTDEEEEDEHPAMPPPRTCGVMAAKAAAAAAGLAGKGQGAFIPISEETVFLDPEPALPSVTTSSPHSGDSWMNYSSNSSDDFSGLSEQIKAVASGRQTCNNSSDDASSDYESSIIGPTEAMFKRYKSQQSFDAATAADSASSPPLTAGNSSVSNGGTTVRSLVSPASSSASSLKSVKGAVKRLRCNDDDQQSASLGESDLREAKKSTITSTPVSAVSSPAKAAPQLRSCESISNQQSLLSGLLLDNNNEQRRNALLQQSSKSLDMSAPPTDDNQCFVDVRLIDFAHTAFVPRNGTMLPTPAAAPVHHGPDGGFLTGLDSLNRLLNEIVAEERA-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12494-1", "uniprot_id": "KCS1_YEAST", "id": "Q12494-1", "name": "Inositol hexakisphosphate kinase 1", "aln": "MDTSHEIHDKIPDTLREQQQHLRQKESEGCITTLKDLNVPETKKLSSVLHGRKASTYLRIFRDDECLADNNNGVDSNNGGSVTCADKITRSEATPKSVPEGLQVSEKKNNPDTLSSSLSSFILSNHEEPAIKPNKHVAHRNNITETGQGSGEDIAKQQSHQPQVLHHQTSLKPIQNVDEGCISPKSTYQESLHGISEDLTLKPVSSATYYPHKSKADSGYEEKDKMENDIDTIQPATINCASGIATLPSSYNRHTFKVKTYSTLSQSLRQENVNNRSNEKKPQQFVPHSESIKEKPNTFEQDKEGEQADEEEDEGDNEHREYPLAVELKPFTNRVGGHTAIFRFSKRAVCKALVNRENRWYENIELCHKELLQFMPRYIGVLNVRQHFQSKDDFLSDLDQENNGKNDTSNENKDIEVNHNNNDDIALNTEPTGTPLTHIHSFPLEHSSRQVLEKEHPEIESVHPHVKRSLSSSNQPSLLPEVVLNDNRHIIPESLWYKYSDSPNSAPNDSYFSSSSSHNSCSFGERGNTNKLKRRDSGSTMINTELKNLVIREVFAPKCFRRKRNSNTTTMGNHNARLGSSPSFLTQKSRASSHDASNTSMKTLGDSSSQASLQMDDSKVNPNLQDPFLKKSLHEKISNALDGSHSVMDLKQFHKNEQIKHKNSFCNSLSPILTATNSRDDGEFATSPNYISNAQDGVFDMDEDTGNETINMDNHGCHLDSGKNMIIKSLAYNVSNDYSHHDIESITFEETSHTIVSKFILLEDLTRNMNKPCALDLKMGTRQYGVDAKRAKQLSQRAKCLKTTSRRLGVRICGLKVWNKD--YYITRDKYFGRRVKVGWQFARVLARFLYDGKTIESLIRQIPRLIKQLDTLYSEIFNLKGYRLYGASLLLMYDGDAN-------------KSNSKRKKAANVKVNLIDFARCVTKEDAMECMDKFRIP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKSPNIEDKGFLRGVKSLRFYLLLIWN------------------------------------------------------------------------------------------------------------------------YLTSDMPLIFDEVEMNDMISEEADSNSFTSATGSKINFNSKWDWLDEFD----KEDEEMYNDPNSKLRQKWRKYELIFDAEPRYNDDAQVSD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: ::. : : .:: ** ::: .: : : : .::: :. : . : : . . : ::.: : . . : . . .. * . . . . ..*. ... : : . . * * ::. . :: : *. . .: *::**::* . . ** *********:* **. * .* ** :** :***:**::.: . :** **.:. * .* *:::* :. . : ::::* * : . ..**:*..***::*:* .: . :* : : *.: : . . *:* . ::.. :. . :. . ", "identical_positions": 58, "similar_positions": 135, "identity": "4.25%" }, { "cls_id": "homologset.agr.RGD:62053", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97315-1", "uniprot_id": "CSRP1_MOUSE", "id": "P97315-1", "name": "Cysteine and glycine-rich protein 1", "aln": "----------------MPNWG--GGKKCGVCQKTVYFAEEVQCE-----GNSFHKSCFLCMVCKKNLDS----------------------------------------------------------------TTVAVHGEEIYCKSCYGKKYG---------------------------PKGYGYG-------------------------------------------------------------------------------------------------QGAGTLSTDKGESLGIKHE-EAPGHRPTTNPNASKFAQ----------------------------------------------------------------------------------------KIGGSERCPRCSQAVYAAEKVIGAGKSWHKSCFRCAKCGKGLESTTLADK-----DGEIYCKGCYAKNFGPK-GFGFGQGAGAL-----VHSE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21291-1", "uniprot_id": "CSRP1_HUMAN", "id": "P21291-1", "name": "Cysteine and glycine-rich protein 1", "aln": "----------------MPNWG--GGKKCGVCQKTVYFAEEVQCE-----GNSFHKSCFLCMVCKKNLDS----------------------------------------------------------------TTVAVHGEEIYCKSCYGKKYG---------------------------PKGYGYG-------------------------------------------------------------------------------------------------QGAGTLSTDKGESLGIKHE-EAPGHRPTTNPNASKFAQ----------------------------------------------------------------------------------------KIGGSERCPRCSQAVYAAEKVIGAGKSWHKACFRCAKCGKGLESTTLADK-----DGEIYCKGCYAKNFGPK-GFGFGQGAGAL-----VHSE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47875-1", "uniprot_id": "CSRP1_RAT", "id": "P47875-1", "name": "Cysteine and glycine-rich protein 1", "aln": "----------------MPNWG--GGKKCGVCQKTVYFAEEVQCE-----GNSFHKSCFLCMVCKKNLDS----------------------------------------------------------------TTVAVHGEEIYCKSCYGKKYG---------------------------PKGYGYG-------------------------------------------------------------------------------------------------QGAGTLSMDKGESLGIKHE-EAPGHRPTTNPNASKFAQ----------------------------------------------------------------------------------------KIGGSERCPRCSQAVYAAEKVIGAGKSWHKSCFRCAKCGKGLESTTLADK-----DGEIYCKGCYAKNFGPK-GFGFGQGAGAL-----VHSE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q24400-1", "uniprot_id": "MLP2_DROME", "id": "Q24400-1", "name": "Muscle LIM protein Mlp84B", "aln": "----------------MPSFQPIEAPKCPRCGKSVYAAEERLAG-----GYVFHKNCFKCGMCNKSLDS----------------------------------------------------------------TNCTEHERELYCKTCHGRKFG---------------------------PKGYGFG-------------------------------------------------------------------------------------------------TGAGTLSMDNGSQFLRENG-DVPSVRNGARLEPRAIAR----------------------------------------------------------------------------------------APEG-EGCPRCGGYVYAAEQMLARGRSWHKECFKCGTCKKGLDSILCCEAP----DKNIYCKGCYAKKFGPK-GYGYGQGGGALQSDCYAHDDGAPQIRAAIDVDKIQARPGEGCPRCGGVVYAAEQKLSKGREWHKKCFNCKDCHKTLDSINASDGPDRDVYCRTCYG-------------------------------------------KKWGPHGYGFACGSGFLQTDGLTEDQISANRPFYNPDTTSIKA------------------RDGEGCPRCGGAVFAAEQQLSKGKVWHKKCYNCADCHR---------PLDSVLACDGPDGDIHCRACYGKLFGPKGFGYGHAPTLVSTSGESTIQFPDGRPLAGPKTSGGCPRCGFAVFAAEQMISKTRIWHKRCFYCSDCRKSLDSTNLNDGPDGDIYCRACYGRNFGPKGVGYGLGAGALTTF-----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35688-1", "uniprot_id": "LRG1_YEAST", "id": "P35688-1", "name": "Rho-GTPase-activating protein LRG1", "aln": "MIQNSAGYRSLNTASPMTVQVKNQKKICARCNKLVIPDSQRTKTTLKALGKYYHESCFTCQDCQKPLKPKYFPYQVDKTSESILLCQYDYFRRHNLLCHVCDTPLRGLYYTAFGYRYDEEHFSCTICATPCGVKKCFMYGNQLYCKYHFLKYFSKRCKGCEFPISDQYIEFPKGEEIHCWHPECYGIHKYWHVNLAAETVGLQYLPKLEYNPNSGDKDINPTAYELDKQMQAFNFILSKTWSVLYRFEEEAASCISDMFQYLTSNDQLKGIESTGLLVLKIDCLFRGLDTLNLSTNKSMPVNSDQECIENNAMAASKYSKFPKNLSTKIMIYLQLLRKLGTENKNETITISSFMSVITGLAHFLKLLTRFGLYTALENNKLTHSVNPLLRFLREVEKNELFENNPFQYIKTPVNATDSCAGCNKYIQEECIQFYEHR-WHIACFTCSSCHKNINPRSLTDPTFNKEKKKILCSHCSIDDPASVPGFKFVTKLAQLIFLLKIALVKSRTVMLKSKASNKVGRNSLQSTMLKEQTYIRTLNDIKRLRSRRESVRVTHNKQQARKSVILETAETDLNDPTKQGDSKNLVIQTDDPSSSQQVSTRENVFSNTKTLTLDDISRIVAAEQARELRPNAFAHFKKLKETDDETSNVVPKKSGVYYSELSTMELSMIRAISLSLLAGKQLISKTDPNYTSLVSMVFSNEKQVTGSFWNRMKIMMSMEPKKPITKTVFGAPLDVLCEKWGVDSDLGVGPVKIRIPIIIDELISSLRQMDMSVEGIFRKNGNIRRLRELTANIDSNPTEAPDFSKENAIQLSALLKKFIRELPQPILSTDLYELWIKAAKIDLEDEKQRVILLIYSLLPTYNRNLLEALLSFLHWTSSFSYIENEMGSKMDIHNLSTVITPNILYLRHKEISNDNVPDEPESGLVDSFAQNKGENYFLAIEIVDYLITHNEEMAMVPKFLMNLLKDVQLQKLDNYESINHFISTVMQSKTIDYSECDIKTPVTVKDSTTTVIQGEINK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * * * * .: * :*:.** * *:* *.. .. : .::*** . : :. *: ** * .**. .....: : : . : : :.: . : *. *. : : : ** ** *..* *.::. : . :* *. * .. .. *: : . * ", "identical_positions": 36, "similar_positions": 60, "identity": "3.54%" }, { "cls_id": "homologset.agr.RGD:620531", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI12-1", "uniprot_id": "VGLU2_RAT", "id": "Q9JI12-1", "name": "Vesicular glutamate transporter 2", "aln": "---MESVKQRILAPGKEGIKNFAGKSLGQIYR-------VLE------KKQDNRETIELTED--GKPLEVPEKKAP-------LCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGK-VIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYG-CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYALFASGEKQPWADP--EE-------------TSEEKCGFIHE---------DELDEETGDITQNYINYGTT---------KSYGATSQENGGWPNGWEKKEEFVQESAQD-AYSYKDRDDYS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLE7-1", "uniprot_id": "VGLU2_MOUSE", "id": "Q8BLE7-1", "name": "Vesicular glutamate transporter 2", "aln": "---MESVKQRILAPGKEGIKNFAGKSLGQIYR-------VLE------KKQDNRETIELTED--GKPLEVPEKKAP-------LCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGK-VIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYG-CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISDGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYALFASGEKQPWADP--EE-------------TSEEKCGFIHE---------DELDEETGDITQNYINYGTT---------KSYGATSQENGGWPNGWEKKEEFVQEGAQD-AYTYKDRDDYS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2U8-1", "uniprot_id": "VGLU2_HUMAN", "id": "Q9P2U8-1", "name": "Vesicular glutamate transporter 2", "aln": "---MESVKQRILAPGKEGLKNFAGKSLGQIYR-------VLE------KKQDTGETIELTED--GKPLEVPERKAP-------LCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGK-VIKEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYG-CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYAIFASGEKQPWADP--EE-------------TSEEKCGFIHE---------DELDEETGDITQNYINYGTT---------KSYGATTQANGGWPSGWEKKEEFVQGEVQD-SHSYKDRVDYS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5W8I7-1", "uniprot_id": "VGL2B_DANRE", "id": "Q5W8I7-1", "name": "Vesicular glutamate transporter 2.2", "aln": "---MDTVKERVLAPGKEKMRNLAGKTLGHMHR-------VME------RKQKTGEVIELTED--GRPMHMPEKKAP-------LVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHKGGKIIIKGKAKFNWDPETVGMIHGSFFWGYTVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIPSAARVHYG-CVMFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGILVQYSGWSSVFYIYGSFGIVWYMFWILVSYESPADHPTITDEERTYIEESIGESAKLLGAMEKYKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMVSALPHLVMTIIVPIGGQLADYLRSKNILTTTTVRKIMNCGGFGMEATLLLVVGFSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKNKTREEWQNVFLIASLVHYGGVIFYGIFASGEKQPWADP--EE-------------TSDEKCGFIDE---------DELAEETGDITLSHAPFGAQGALG--APAKTYGATTQLNGGWAKGWEKTEEFIQEDAER-TYTG---DGYS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5W8I8-1", "uniprot_id": "VGL2A_DANRE", "id": "Q5W8I8-1", "name": "Vesicular glutamate transporter 2.1", "aln": "---METPRE-PAGFSKEGLKQLAGKTLGHVYR-------VIE------KRQKPGENIELTED--GRPAQINERKAP-------LCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTIHLNGKIIIKEKAKFNWDPETVGLIHGSFFWGYIVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIPSAARGHYG-CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGCFGIFWYMFWILVSYESPAEHPTITAEERCYIEESIGESAKLLGPADKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSALPHLVMTIIVPIGGQLADHLRSKNILSTTTVRKIMNCGGFGMEATLLLIVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQYVFLIASLVHYGGVIFYGIFASGEKQPWADP--EL-------------TSDEKCGFIDE---------DELAEETGDITQSYGALGAP--------AKSYGATTQLNGGWAEGWDKREEYVQDGVEEGGYGYRQGGNYS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQC0-1", "uniprot_id": "Q9VQC0_DROME", "id": "Q9VQC0-1", "name": "", "aln": "MKGLTAFKEKATGVFGGLKPNMEKFEISQSYHGGHGGYEEMEGGDREGRGPGGGHAYDDDDDRPDSPASFEEIERPPLRKIDKYCKAECPCMPARYTIATMACVGFMIAFGMRCNMSAAKLKGEHNGTVF------------MNWTVAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIFGLSIVSSATLHLFVPFAMTLMHGHVVICVRVLQGLFEGVTYPACHGIWRFWAPPMERSRLATLAFSGSYAGVVVGLPLSGLLADAVGYQAPFYAYGVFGIIWYMFWIWLCFENPRKHPAISIPELKYIEKSLGESAHPTMPSLKT-TPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADHLRKNGILSTTNVRKLFNCGGFGMEGLFFLFVAHSSTATGAMFALTCGVAFSGFAISGYNVNHLDIAPRYASILMGLSNGIGTLAGIIVPYALDGLIQANPTGCWTTVFTLAACVHLVGCTFYGIFASGELQPWAEPPAEEQKVWAPPPGAITNTDPSQAGMLGDYMKETSFGAPEYTEQSQMQQSTAISYGATGHVANNPFAMASGAPPIAEEDAPPTYGDVTNPGQYGYTQGQMPSYDPQGYQQQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: . :: :.: :: :* : . : :* . * . * : * .. * :* ** ** *: :** *:**:***:..* :. :*.*:. :** . . :..****** :******:*:*::.**::** :*: ::**::::* * :* *: **:****.************ ****:******* :*.*****.*:.:**:*:*.: *:.: ** ** **:.*****: :.:*.* .**:*: * ***:*:****: . * ****::: ****************.****:: *.::::. ***::.:.*::.::***:** ***:** :**.**.: **:**.***::********. ::*.*..* : *: *. .*.********:*****************:*:*:***:*:: * :..: : :. * ** :*: ** * **.:***** ****:* * *. .:.*:: : * *:: . *: : **.. : . . : . : * .*. ", "identical_positions": 242, "similar_positions": 174, "identity": "37.52%" }, { "cls_id": "homologset.agr.RGD:620532", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O09028-1", "uniprot_id": "GBRP_RAT", "id": "O09028-1", "name": "Gamma-aminobutyric acid receptor subunit pi", "aln": "-------------------MSYS---LYLAFVCLNLLAQRMCIQGNQFNVEVSRSDKLSLPGFENLTAGYNKFLRPNFGGDPVRIALTLDIASISSISESNMDYTATIYLRQRWTDPRLVFE---GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSKYPMDTQTCKLQLESWGYDGNDVEFSWLRGNDSVRGLENLRLAQYTIQQYFTLVTVSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLESVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSS----LQQMAVKD--RGPAKDSEEVNITNIINSSISS--------------------------------------------FKRKISFAS-IEISGDNVNYSDLTMKASDKFK-----------------------------------------------------------------------------FVFREKIGRIIDYFTIQNPSNVDRYSKLLFPLIFMLANVFYWAYYMYF--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZW7-1", "uniprot_id": "GBRP_MOUSE", "id": "Q8QZW7-1", "name": "Gamma-aminobutyric acid receptor subunit pi", "aln": "-------------------MSYS---LYLAFLCLSLLTQRTCIQGNQVNVEVSRSDKLSLPGFENLTAGYNKFLRPNFGGDPVRIALTLDIASISSISESNMDYTATIYLRQRWTDPRLVFE---GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSKYPMDTQTCKLQLESWGYDGNDVEFSWLRGNDSVRGLENLRLAQYTIQQYFTLVTVSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSS----LQQMAVKD--RGPAKDSEEVNITNIINSSISS--------------------------------------------FKRKISFAS-IEISGDNVNYSDLTMKASDKFK-----------------------------------------------------------------------------FVFREKISRIIDYFTIQNPSNVDRYSKLLFPLIFMLANVFYWAYYMYF--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00591-1", "uniprot_id": "GBRP_HUMAN", "id": "O00591-1", "name": "Gamma-aminobutyric acid receptor subunit pi", "aln": "-------------------MNYS---LHLAFVCLSLFTERMCIQGSQFNVEVGRSDKLSLPGFENLTAGYNKFLRPNFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFE---GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSS----LQQMAAKD--RGTTKEVEEVSITNIINSSISS--------------------------------------------FKRKISFAS-IEISSDNVDYSDLTMKTSDKFK-----------------------------------------------------------------------------FVFREKMGRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYYMYF--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BL14-1", "uniprot_id": "A0A8M2BL14_DANRE", "id": "A0A8M2BL14-1", "name": "Gamma-aminobutyric acid receptor subunit pi", "aln": "-----MICISDLHSYQSSGLHYHRMLLNLLFWTSLFLLITNGERGFYGNQYGEWNDSQLQPTIQKLMKGYNRYLRPNFNEGPVEIGMSLDIASIDAISEINMDYTATIFLRQRWRDSRLIFP---GNESLSLDGRLVSLLWIPDTFIPDSKRSFLHDVTVENRLIRIFSNGTVLYALRITATIACNMDLTKYPMDRQECTLQLESWGYNLEDVVFYWTRGNDSVKGLDTLRLAQYSVESYYTSVTKAVYETGLYPKLILHFALRRNVLFFILETYVPSTLLVVLSWVSFWISQSSVPARTCIGVTTVLTMTTLMMGARTSLPNANCFIKAIDVYLGICFTFIFGALLEYACAHFCT----MQHQTIIDVQRELLKEFEESNGTTHLVSSMSP--------------------------------------------RKMKTEDSTKQEKPEQTVTCEENEAVEQTKEKGCG-------------------------------------------------------------------------LTTVKQMSRRAASMMSVENPHNIDRHARILFPMAFLLINIFYWLYYLLF--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25123-2", "uniprot_id": "GBRB_DROME", "id": "P25123-2", "name": "Gamma-aminobutyric acid receptor subunit beta", "aln": "MSDSKMDKLARMAPLPRTPLLTIWLAINMALIAQETGHKRIHTVQAATGGGSMLGDVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALP-KISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVADDLVLLGEE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . .* . ::.: .*:: :***:. **.:.::: : **.::** :**:* :::** * * ** : * :::::...::. :*:***:: :.*:*::* .*. *.:**:. .*:: ::*:* * :* *:* :*** * * :::**:** .*: : * .* :** . : *.*:.: : . ** *.:* .: : *.: ::::: *:** ::*::******:. .:.***..:******:***** .:.::** .::*:****** ** ::*.:***** . : : ::: : :. :: . :. :. .. . :. . : .: : : . : .* ::*::::::**: *: *::** *: . ", "identical_positions": 110, "similar_positions": 168, "identity": "18.12%" }, { "cls_id": "homologset.agr.RGD:620533", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23978-1", "uniprot_id": "SC6A1_RAT", "id": "P23978-1", "name": "Sodium- and chloride-dependent GABA transporter 1", "aln": "MATDNSKVADG----------QISTEVSEAP-VASDKPKTLVVKVQK---KAGDLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYS---------LVN---------------TTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMGSYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRLQVMIQPSEDIVRPENGPEQPQAGSSASKEAYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31648-1", "uniprot_id": "SC6A1_MOUSE", "id": "P31648-1", "name": "Sodium- and chloride-dependent GABA transporter 1", "aln": "MATDNSKVADG----------QISTEVSEAP-VASDKPKTLVVKVQK---KAGDLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYS---------LVN---------------TTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMGSYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRLQVMIQPSEDIVRPENGPEQPQAGSSASKEAYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30531-1", "uniprot_id": "SC6A1_HUMAN", "id": "P30531-1", "name": "Sodium- and chloride-dependent GABA transporter 1", "aln": "MATNGSKVADG----------QISTEVSEAP-VANDKPKTLVVKVQK---KAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYS---------MVN---------------TTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPENGPEQPQAGSSTSKEAYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V4E7-1", "uniprot_id": "Q9V4E7_DROME", "id": "Q9V4E7-1", "name": "Transporter", "aln": "MYTNSASDGDGGGDVCKHESIEMSKELGHTTSLQSSSPTTTDTSNKQQLVKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTDPVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWWAHAFGWFTALSSMLYIPLYMFWLWKRTPGELSEKIRALVRIDEDVTRLREKMLREAYAKEIEFNSL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:.:. .** ::*.*:..:. : ...*.* .. :: * :****.:*..::**::* ** ************** *******::**::**::**:*:*::* :*** :******:*:**:***:* ****:* *:*:*****::**::*:: *: : :**: *:* *** .*.*:*. ::* : ::*..* *****. *::.*::: *:*** ** ** :.*:* ******** ********:* :**::* **:.**:***** *** *** *** **::****:**.************:*:******.* ****:*::*** :**.***********::***** :*.:*************.**.** *** **:*: *** ***::*:******:******::**:*:***:*:*:*** ** :***:**: *****:*:*:::* *:.**:.**:*:********* ***:****.*::*:* * :***:**.. ** * ***:*. ** **:. .* :* *.:..**: *****: ** ** ::: *.*.::::.::: .**:.* .: : ... . :: ", "identical_positions": 333, "similar_positions": 182, "identity": "52.28%" }, { "cls_id": "homologset.agr.RGD:620535", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4S7-1", "uniprot_id": "CBLB_RAT", "id": "Q8K4S7-1", "name": "E3 ubiquitin-protein ligase CBL-B", "aln": "MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQE-SDGQGCPFCRCEIKGTEPIIVDPFDPRDEGSRCCSIIDPFSIPMLDLDDDDDREESLMMNRLASVRKCTDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPP-ERPPPIPPDSRLSRHFHHGESVPSRDQPMPLEAWCPRDAFGTNQVMGCRILGDGSPKPGVTANSNLNGRHSRMGSDQVLMRKHRRHDLPSEGAKVFSNGHLAPEEYDVPPRLSPPPPVTALLPSIKCTGPIANCLSEKTRDTVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCILNGTHGTPSEMKKSNIPDLGIYLKG--------------------------------------------EDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFFDPASGQVPLPPARRAPGDGVKSNRASQDYDQLPSSSDGSQAPARPPKPRPRRTAPEIHHRKPHGPEAALENVDAK-IAKLMGEGYAFEEVKRALEIAQNNLEVARSILREFAFPPPVSPRLNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TTA7-1", "uniprot_id": "CBLB_MOUSE", "id": "Q3TTA7-1", "name": "E3 ubiquitin-protein ligase CBL-B", "aln": "MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQE-SDGQGCPFCRCEIKGTEPIIVDPFDPRDEGSRCCSIIDPFSIPMLDLDDDDDREESLMMNRLASVRKCTDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPP-ERPPPIPPDNRLSRHFHHGESVPSRDQPMPLEAWCPRDAFGTNQVMGCRILGDGSPKPGVTANSSLNGRHSRMGSEQVLMRKHRRHDLPSEGAKVFSNGHLATEEYDVPPRLSPPPPVTTLLPSIKCTGPLANCLSEKTRDTVEDDDDEYKIPSSHPVSLNSQPSHCHNVKAPVRSCDNGHCILNGTHGAPSEMKKSNIPDLGIYLKGGGSDSASDPVPLPPARPPPRDSPKHGSSVNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFFDPTSGQVPLPPARRAAGDSGKANRASQDYDQLPSSSDGSQAPARPPKPRPRRTAPEIHHRKPHGPEAALENVDAK-IAKLMGEGYAFEEVKRALEIAQNNVEVARSILREFAFPPPVSPRLNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13191-1", "uniprot_id": "CBLB_HUMAN", "id": "Q13191-1", "name": "E3 ubiquitin-protein ligase CBL-B", "aln": "MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQE-SDGQGCPFCRCEIKGTEPIIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHG-PSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIHHRKPHGPEAALENVDAK-IAKLMGEGYAFEEVKRALEIAQNNVEVARSILREFAFPPPVSPRLNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSK2-1", "uniprot_id": "Q9VSK2_DROME", "id": "Q9VSK2-1", "name": "E3 ubiquitin-protein ligase CBL", "aln": "MATRGSGTRVQSQP-KIFPSLLSKLHGAISEACVS-QRLSTDKKTLEKTWKLMDKVVKLCQQPKMNLKNSPPFILDILPDTYQRLRLIYSKNED--QMHLLHANEHFNVFINNLMRKCKQAIKLFKEGKEKMFDENSHYRRNLTKLSLVFSHMLSELKAIFPNGVFAGDQFRITKADAADFWKSNFGNSTLVPWKIFRQELNKVHPIISGLEAMALKTTIDLTCNDFISNFEFDVFTRLFQPWVTLLRNWQILAVTHPGYVAFLTYDEVKARLQRYILKAGSYVFRLSCTRLGQWAIGYVTAEGEILQTIPQNKSLCQALLDGHREGFYLYPDGQAYNPDLSSAVQSPTEDHITVTQEQYELYCEMGSTFQLCKICAENDKDIRIEPCGHLLCTPCLTSWQVDSEGQGCPFCRAEIKGTEQIVVDAFDPRKQHNRNVTNGR---QQQQEEDDTEDIGDFNIATSSLHALSTSSTVAAEKHSPHTSPRLGRRSTTPSLMAVQNDLYAGGTPTLSLPS-----SSCSSIAAASTSSSSSLASVATVAASTSSSQHQQPQPS------APPASAVLSNGGGGGGGGGASSSQKNTNRMSAPLIGS--CVANSTYGQKLPQNCSHSSTSSSSDNASSSSSYAILQNLHDTGTPATAAAVVAP--------PLPPRKSSP----GVETPSKATAPPPPSSSKSIDNIQCSLDNVPPQTTAPPIPPHVSPSVDTLAEDLMR----QQLIATSTTSPVLSLLDEDIVEVG----------------------------------------------------------------PAETISGVIDTRPLEARGVTLCRQDSASSHYTQLCTTSSGGSAAALANGKKANSAKQSQATTTTSAAAAAATAGNGSNPGQQSQPLLYANVTINQKDCG-TVPYENINLEYIARLMNAGYSKENAITALGISRNNIEMAGDILREFVSKNSA------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. .* . .: : . : : .**.:* . :: ::*::*:***********:***:**::******:**********:**** ** :* :: * **:*:::*:.**:*.*:**:*******:*::*:*: *********:*****:*:******* * **:*********:**:. **:.*:****:*** *::** * *********:********:** ****:******** ::****::********:*************:* *.***:*****************.:*:******:**.* ***:** **********::*****:. :....***.****************************::*******:**.***:** *:********.****** *:**.****.: .* : : ** :* : : . . . :. : ** :** **.. *. : : : . .* *.* . *.*.* :.:..**.. : . . .:.... :: * *. ** . : : . . . . . :*: :. *: *: :.:. .. :: .*. .:::: : . * .* *.: :*** *.* : .. *.*.* . . *:. : . *: .:: *:. : .** .: :* : : ..* . . ..:* ::. *. * : .::* : . . . ** : :** . . *. .:. * .::: . .:.: ..:.. :.:* * ::* * .. **:: : **:**. **: *:. ** *::**:*:* .*****. .. ", "identical_positions": 373, "similar_positions": 263, "identity": "37.87%" }, { "cls_id": "homologset.agr.RGD:620536", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MC0-1", "uniprot_id": "PP14A_RAT", "id": "Q99MC0-1", "name": "Protein phosphatase 1 regulatory subunit 14A", "aln": "--MAAQRLGKRVLSKLQSPSRARGPGGSPSGLQKRHARVTVKYDRREL---QRRLDVEKWIDGRLEELYRGREADMPDEVNIDELLELDSEEERCRKIRGLLEACLNP---TEDFVQELLAKLRGLHKQPGFPQPSPSDDPSLSPRQDPAHTAPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VC7-1", "uniprot_id": "PP14A_MOUSE", "id": "Q91VC7-1", "name": "Protein phosphatase 1 regulatory subunit 14A", "aln": "--MAAQRLGKRVLSKLQSPSRARGPGGSPSGLQKRHARVTVKYDRREL---QRRLDVEKWIDGCLEELYRGRESDMPDEVNIDELLELDSEEERCRKIQGLLEACANP---TEDFVQELLAKLRGLHKQPGFPQPSPSDDPSLSPRQDRAHTAPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A00-1", "uniprot_id": "PP14A_HUMAN", "id": "Q96A00-1", "name": "Protein phosphatase 1 regulatory subunit 14A", "aln": "--MAAQRLGKRVLSKLQSPSRARGPGGSPGGLQKRHARVTVKYDRREL---QRRLDVEKWIDGRLEELYRGMEADMPDEINIDELLELESEEERSRKIQGLLKSCGKP---VEDFIQELLAKLQGLHRQPGLRQPSPSHDGSLSPLQDRARTAHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKQ5-1", "uniprot_id": "Q9VKQ5_DROME", "id": "Q9VKQ5-1", "name": "", "aln": "MQCGLEQMNDCERSPNRTNLRVNFNEKGAEVKERREKFLTAKYGSHQMSLIRKRLAVEMWLYDELQKLFD--PPNEAIDVDIDEILDMDTDDIRRSHLIRLLSVCKRPQSDISKFIGDLLDRAKTL-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :::.. * :: *.. .. ::*. :*.**. ::: ::** ** *: . *::*: .: . :::***:*:::::: * :: **. * .* ..*: :** : : * ", "identical_positions": 26, "similar_positions": 51, "identity": "16.77%" }, { "cls_id": "homologset.agr.RGD:620537", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O09047-1", "uniprot_id": "C3AR_MOUSE", "id": "O09047-1", "name": "C3a anaphylatoxin chemotactic receptor", "aln": "MESFDADTNSTDLHSRPLFQPQDIASMVILGLTCLLGLLGNGLVLWVAGVKMKTTVNTVWFLHLTLADFLCCLSLPFSLAHLILQGHWPYGLFLCKLIPSIIILNMFASVFLLTAISLDRCLIVHKPIWCQNHRNVRTAFAICGCVWVVAFVMCVPVFVYRDLFIMDNRSICRYNFDSSRSYDYWDYVYKLSLPESNSTDNSTAQLTGHMNDRSAP-SSVQARDYFWTVTTALQSQPFLTSPEDSFSLDSA--NQQPHYG--GKPPNVLTAAVPSGFPVEDRKSNTLN-ADAFLSAHTELFPTASSGHLYPYDFQGDYVD-----QFTYDNHVPTPLMAITITRLVVGFLVPFFIMVICYSLIVFRMRKTNFTKSRNKTFRVAVAVVTVFFICWTPYHLVGVLLLITDPESSLGEAVMSWDHMSIALASANSCFNPFLYALLGKDFRKKARQSIKGILEAAFSEELTHSTNCTQDKASSKRNNMSTDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55197-1", "uniprot_id": "C3AR_RAT", "id": "O55197-1", "name": "C3a anaphylatoxin chemotactic receptor", "aln": "MESFTADTNSTDLHSRPLFKPQDIASMVILSLTCLLGLPGNGLVLWVAGVKMKRTVNTVWFLHLTLADFLCCLSLPFSVAHLILRGHWPYGLFLCKLIPSVIILNMFASVFLLTAISLDRCLMVHKPIWCQNHRSVRTAFAVCGCVWVVTFVMCIPVFVYRDLLVVDDYSVCGYNFDSSRAYDYWDYMYNSHLPEINPPDNS----TGHVDDRTAPSSSVPARD-LWTATTALQSQTFHTSPEDPFSQDSA--SQQPHYG--GKPPTVLIATIPGGFPVEDHKSNTLN-TGAFLSAHTEPSLTASSSPLYAHDFPDDYFD-----QLMYGNHAWTPQVAITISRLVVGFLVPFFIMITCYSLIVFRMRKTNLTKSRNKTLRVAVAVVTVFFVCWIPYHIVGILLVITDQESALREVVLPWDHMSIALASANSCFNPFLYALLGKDFRKKARQSVKGILEAAFSEELTHSTSCTQDKAPSKRNHMSTDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16581-1", "uniprot_id": "C3AR_HUMAN", "id": "Q16581-1", "name": "C3a anaphylatoxin chemotactic receptor", "aln": "MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIWFLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDRCLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSSSLDYPDFYGDP--LENRSLENIVQP-PGEMNDRLDP-SSFQTNDHPWTVPTVFQPQTFQRPSADSLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSASSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIVFRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVCIALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERN--STTV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** *:****** *:* :* * *****.** **** **********:**: ****:*********:*********:*** *:*:**** ********:*:*******************:*.*********.* * ::***:***:****:******::: *: . * *:*. * : ** *: . * .. :* .*.::** * **. :.* **..*.:*.*.* .. *.:. .** ..* *. **. *: . :*.***:**:::..*: :.****:* : :***. :* :: .: * *: .::. ** :****:*******:* .**: ***:*****:: .::**:.**:****.**:**::** ***:.*:* ::** *:.* :.::.***:.*****************************::************:** *..::. *:** ** *", "identical_positions": 273, "similar_positions": 125, "identity": "55.94%" }, { "cls_id": "homologset.agr.RGD:620538", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4R9-1", "uniprot_id": "PP14C_RAT", "id": "Q8R4R9-1", "name": "Protein phosphatase 1 regulatory subunit 14C", "aln": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQ-RRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKP---TEEFIRELLSRIRGMRKLSPPQKKSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4S0-1", "uniprot_id": "PP14C_MOUSE", "id": "Q8R4S0-1", "name": "Protein phosphatase 1 regulatory subunit 14C", "aln": "MSVVTGGGEAAGGGGGGGARVFFQSPRGGTGGSPGSSSSSGSSREDSAPVTTVAAAGQVQQQQ-RRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDANSEEERASKLQEALVDCYKP---TEEFIRELLSRIRGMRKLSPPQKKSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAE6-1", "uniprot_id": "PP14C_HUMAN", "id": "Q8TAE6-1", "name": "Protein phosphatase 1 regulatory subunit 14C", "aln": "MSVATGSSETAGGASGGGARVFFQSPRGGAGGSPGSSSGSGSSREDSAPVATAAAAGQVQQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPEVEIDIDDLLDADSDEERASKLQEALVDCYKP---TEEFIKELLSRIRGMRKLSPPQKKSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKQ5-1", "uniprot_id": "Q9VKQ5_DROME", "id": "Q9VKQ5-1", "name": "", "aln": "----------------------------MQCGLEQMNDCERSPNRTNLRVNFNEKGAEVKERR-EKFLTAKYGS-HQMSLIRKRLAVEMWLYDELQKLFDPPNE---AIDVDIDEILDMDTDDIRRSHLIRLLSVCKRPQSDISKFIGDLLDRAKTL-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .. . *... . * ..:*:::: .:. .* :: . :****.:* *: ::* :*:. :* :::***::** :::: * *:* . * * :* .:** :**.* : : ", "identical_positions": 30, "similar_positions": 49, "identity": "17.86%" }, { "cls_id": "homologset.agr.RGD:620539", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923K1-1", "uniprot_id": "TS1R3_RAT", "id": "Q923K1-1", "name": "Taste receptor type 1 member 3", "aln": "MPGLAILGLSLAAFLELGMGSSLCLSQQFKAQGDYILGGLFPLGTTEEATLNQRTQPNGILCTRFSPLGLFLAMAMKMAVEEINNGSALLPGLRLGYDLFDTCSEPVVTMKPSLMFMAKVGSQSIAAYCNYTQYQPRVLAVIGPHSSELALITGKFFSFFLMPQVSYSASMDRLSDRETFPSFFRTVPSDRVQLQAVVTLLQNFSWNWVAALGSDDDYGREGLSIFSGLANSRGICIAHEGLVPQHDTSGQQLGKVVDVLRQVNQSKVQVVVLFASARAVYSLFSYSILHDLSPKVWVASESWLTSDLVMTLPNIARVGTVLGFLQRGALLPEFSHYVETRLALAADPTFCASLK-AELDLEERVMGPRCSQCDYIMLQNLSSGLMQNLSAGQLHHQIFATYAAVYSVAQALHNTLQCNVSHCHTSEPVQPWQLLENMYNMSFRARDLTLQFDAKGSVDMEYDLKMWVWQSPTPVLHTVGTFNGTLQLQHSKMYWPG--NQVPVSQCSRQCKDGQVRRVKGFHSCCYDCVDCKAGSYRKHPDDFTCTPCGKDQWSPEKSTTCLPRRPKFLAWGEPAVLSLLLLLCLVLGLTLAALGLFVHYWDSPLVQASGGSLFCFGLICLGLFCLSVLLFPGRPRSASCLAQQPMAHLPLTGCLSTLFLQAAEIFVESELPLSWANWLCSYLRGPWAWLVVLLATLVEAALCAWYLMAFPPEVVTDWQVLPTEVLEHCRMRSWVSLGLVHITNAVLAFLCFLGTFLVQSQPGRYNRARGLTFAMLAYFIIWVSFVPLLANVQVAYQPAVQMGAILFCALGILATFHLPKCYVLLWLPELNTQEFFLGRSPKEASDGNSGSSEATRGHSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q925D8-1", "uniprot_id": "TS1R3_MOUSE", "id": "Q925D8-1", "name": "Taste receptor type 1 member 3", "aln": "MPALAIMGLSLAAFLELGMGASLCLSQQFKAQGDYILGGLFPLGSTEEATLNQRTQPNSIPCNRFSPLGLFLAMAMKMAVEEINNGSALLPGLRLGYDLFDTCSEPVVTMKSSLMFLAKVGSQSIAAYCNYTQYQPRVLAVIGPHSSELALITGKFFSFFLMPQVSYSASMDRLSDRETFPSFFRTVPSDRVQLQAVVTLLQNFSWNWVAALGSDDDYGREGLSIFSSLANARGICIAHEGLVPQHDTSGQQLGKVLDVLRQVNQSKVQVVVLFASARAVYSLFSYSIHHGLSPKVWVASESWLTSDLVMTLPNIARVGTVLGFLQRGALLPEFSHYVETHLALAADPAFCASLN-AELDLEEHVMGQRCPRCDDIMLQNLSSGLLQNLSAGQLHHQIFATYAAVYSVAQALHNTLQCNVSHCHVSEHVLPWQLLENMYNMSFHARDLTLQFDAEGNVDMEYDLKMWVWQSPTPVLHTVGTFNGTLQLQQSKMYWPG--NQVPVSQCSRQCKDGQVRRVKGFHSCCYDCVDCKAGSYRKHPDDFTCTPCNQDQWSPEKSTACLPRRPKFLAWGEPVVLSLLLLLCLVLGLALAALGLSVHHWDSPLVQASGGSQFCFGLICLGLFCLSVLLFPGRPSSASCLAQQPMAHLPLTGCLSTLFLQAAETFVESELPLSWANWLCSYLRGLWAWLVVLLATFVEAALCAWYLIAFPPEVVTDWSVLPTEVLEHCHVRSWVSLGLVHITNAMLAFLCFLGTFLVQSQPGRYNRARGLTFAMLAYFITWVSFVPLLANVQVAYQPAVQMGAILVCALGILVTFHLPKCYVLLWLPKLNTQEFFLGRNAKKAADENSGGGEAAQGHNE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTX0-1", "uniprot_id": "TS1R3_HUMAN", "id": "Q7RTX0-1", "name": "Taste receptor type 1 member 3", "aln": "MLGPAVLGLSLWALLHPGTGAPLCLSQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQYQPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHEGLVPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPKVWVASEAWLTSDLVMGLPGMAQMGTVLGFLQRGAQLHEFPQYVKTHLALATDPAFCSALGEREQGLEEDVVGQRCPQCDCITLQNVSAGLN--------HHQTFSVYAAVYSVAQALHNTLQCNASGCPAQDPVKPWQLLENMYNLTFHVGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGSLRTERLKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAAEIFVESELPLSWADRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALVHCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGCYNRARGLTFAMLAYFITWVSFVPLLANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFFLGGGPGDAQGQNDGN-TGNQGKHE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *::**** *:*. * *:.******:: :***:******** :*** *..**:*.. *.***. **: *:*********** * ********************:**.****:**.**:.**************************::***************.***: ** ****************** *.. ***:*.***********:***:******.** :************ :...:**** ***:*****.****:****.:*.::**.*** **********:******** **.:*::*********** * **.:**:*:****:**:**::* * .*** *:* **.:** * ***:*:** *** *:.******************.* * ..: * **********::*:. .*.*:**:.*.********:****...* ** ** ***:*: :: *: * ** ***:*****::*******************:*****::***::** *.:*:****:** *: **.:*******.** *****.*.***.****** **: **********. ****:****.*********:* .* ******::***************** ***********: *.. *** ********* :**.***:***:********** :****.* **: *****:**.* *** ************:**** **************** *************. :*******:*.*.****.:****:**:*: * *** ***** .. .* . *.*. . :*: *", "identical_positions": 607, "similar_positions": 156, "identity": "70.5%" }, { "cls_id": "homologset.agr.RGD:62054", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06300-1", "uniprot_id": "PDYN_RAT", "id": "P06300-1", "name": "Proenkephalin-B", "aln": "-MAWSRLMLAACLLVIPSEVAADCLSLCSLCAVRTQDGPHPINPLICSLECQDLVPPSEEWETCRGFWSFLTLTASGLHGKDD-----LENEVALEEGYTALTKLLEPLLKELEKGQ--LLTSVS----------EEKLRGLSSRFGNGRESELLGTDLMNDEAAQAGTLHFNEEDLRKQAKRYGGFLRKYPKRSSEMTGDEDRGQDGDQVGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRSQENPNTYS-EDLDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35417-1", "uniprot_id": "PDYN_MOUSE", "id": "O35417-1", "name": "Proenkephalin-B", "aln": "-MAWSRLMLAACLLVMPSNVMADCLSLCSLCAVRIQDGPRPINPLICSLECQDLVPPSEEWETCRGFSSFLTLTVSGLRGKDD-----LEDEVALEEGISAHAKLLEPVLKELEKSR--LLTSVP----------EEKFRGLSSSFGNGKESELAGADRMNDEAAQGRTVHFNEEDLRKQAKRYGGFLRKYPKRSSEMARDEDGGQDGDQVGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRSQENPNTYS-EDLDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01213-1", "uniprot_id": "PDYN_HUMAN", "id": "P01213-1", "name": "Proenkephalin-B", "aln": "-MAWQGLVLAACLLMFPS-TTADCLSRCSLCAVKTQDGPKPINPLICSLQCQAALLPSEEWERCQSFLSFFTPSTLGLNDKED-----LGSKSVGEGPYSELAKLSGSFLKELEKSK--FLPSISTKENTLSKSLEEKLRGLSDGFREGAESELMRDAQLNDGAMETGTLYLAEEDPKEQVKRYGGFLRKYPKRSSEVAGE----GDGDSMGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRSQEDPNAYSGELFDA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B6F1-1", "uniprot_id": "A0A8M3B6F1_DANRE", "id": "A0A8M3B6F1-1", "name": "Proenkephalin-B", "aln": "MMEWYVLVL---MLSFPTLSQADCSAQCLRCAQQISDLDSAVNRLTCTLECEGAVPPTGTLDRCEKALQGLSDDLAELNTGADGETNALNTDEDLQEKTSNLVKRYGGFIKRIDKNKNKFFSSPWKENAILKGLFAKKYGESLSKLGERDLPSITEDDEGEDMGAENETGVYDNEVPLNEVKRYGGFLRKFGPKRSYFVDD---------TNPQVLQKRYGGFMRRIRPKLRWDNQKRYGGFLRRHFKISVRSDEEPSSYEDYAL--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *:* :* :*: *** : * ** : .* .:* * *:*:*: : *: : *. . :: *. * * . : : .* .:*.::*.: ::.* :* . : : ..: :* . : * :* ::.*********: : * .. : . : * ******:*******:*************:**: .**:*:*.:*. : ", "identical_positions": 75, "similar_positions": 66, "identity": "28.09%" }, { "cls_id": "homologset.agr.RGD:620541", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMC1-1", "uniprot_id": "PI5PA_RAT", "id": "Q9JMC1-1", "name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A", "aln": "MEGQSRSGSAKSGTRTGLGPLPGTHGALQTGTPSKKVNSSFQLPAK-NTGPTPSEPRLALAPVGPRAAVSPPSERPRLALSSPRPILAPLSTAGEQKRPPPHRSSKPAPTSVGQLVVSAAAGPKPPPVASVSILAPKSLGQLVISASAMPRPTPAPLGPILSPTSRDQKQLSPTSVGPKPALATSGLSLALASQEQPPQSPSSPSPVPSPVLSPSQESHLAPATVTSTPASERQLPARQKDTAVRRPIPPADGCLHTPVQAAGLATSPPRAQTSSDPRLSPSFRARPEAPRHSPEDPVLPPPPQTLPLDVSSGLPESGTRSPGLLSPTFRPGIPSNQTVPPPLPKPPRSPSRSPSRSPNRSPCVPPAPEVALPRPVTQGAGPGKCPSPNLQTQESPVATAT--SPTSS----WSAQPTCKSDPGFRITVVTWNVGTAMPP-DDVTSLLHLG--------GGHDSDGADMIAIGLQEVNSMINKRLKDALFTDQWSELFMDALGPFNFVLVSTVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAHGILDHDLVFWFGDLNFRIESYD--LHFVKFAIDSNQLHQLWEKDQLNMAKN-TWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPSGGPSPSGRES------HRLQVTQHSYRSHMEYTVSDHKPVAARFLLQFAFRDDVPLVRLEVADEWARPEQAVVRYRVETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKHEEVDGN--IYQVTFSEESLPKGHGDFILGYYSHHHSILIGVTEPFQISLPTSESASSS-TDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPSLALRPSSRERRGGSRSPSPQSRQLPRVAPDRGHSSGSRGSSEEGPSGPPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDQEAPDPNSLSPSPQGRLGLEDGGLGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59644-1", "uniprot_id": "PI5PA_MOUSE", "id": "P59644-1", "name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A", "aln": "MEGQTRSGSARPGTRTGLGPLPGTHGVLQAEIPSKKVNSSFQLPAK-NSGPASSEPRLTLAPVGPRAAVSPPSERPRLVLSSPRPVLAPLSIAGEQKRPPPPHSSNRAAKSVGQLVVSAAAASKPPPVASVSILAPKSLGQLVISASAMPRPSPAPLGSVLTPTSRDQKQLSPTSVGPKPALATSGLSLALASQEQPPQSPSSPSPVPSPVLSPSQEGHLAAASVTSTPASERQLPARQKDTAVPRPTPPADKCLYTPERAAGPATSPPRAQAFSDPRLSPSFRARPEAPRHSPEDPVLPPPPQTLPLDVSPGLPESGTRSPGLLSPTFRPGIPSSQTVPPPLPKPPRSPSRSPSRSPNRSPCLPPAPEVALPKPVTQAAGSGRCPSPNLQAQESPAAATTTTSPTSS----WSAQPTCKSDPGFRITVVTWNVGTAMPP-DDVTSLLHLG--------SGHDNDGADMIAIGLQEVNSMINKRLKDALFTDQWSELFMDALGPFNFVLVSTVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAHGILDHDLVFWFGDLNFRIESYD--LHFVKFAIDSNQLHQLWEKDQLNMAKN-TWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPSGGPSPSGRES------HRLQVTQHSYRSHMEYTVSDHKPVAAQFILQFAFRDDVPLVRLEVADEWARPEQAVVRYRVETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKHEEVDGN--IYQVTFSEESLPKGHGDFILGYYSHHHSILIGVTEPFQISLPTSESASSS-TDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPSLALHPSSRERRGGSRSPSPQSRQLPRVAPDRGHSSSSRGSSEEGPSGLPGPWAFPPSVPRSLGLLPALRLETVDPGGGGSWGADQEAPDPNSLSPSPQGRLGLEEGGLGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15735-1", "uniprot_id": "PI5PA_HUMAN", "id": "Q15735-1", "name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A", "aln": "MEGQSSRGSRRPGTRAGLGSLPMPQGVAQTGAPS-KVDSSFQLPAKKNAALGPSEPRLALAPVGPRAAMSASSEGPRLALASPRPILAPLCTPEGQKTATAHRSSSLAPTSVGQLVMSASAGPKPPPATTGSVLAPTSLG-LVMPASAGPRSPPVTLGPNLAPTSRDQKQEPPASVGPKPTLAASGLSLALASEEQPPELPSTPSPVPSPVLSPTQEQALAPASTASGAASVGQTSARKRDAPAPRPLPASEGHLQPPAQTSGPTGSPPCIQTSPDPRLSPSFRARPEALHSSPEDPVLPRPPQTLPLDVGQGPSEPGTHSPGLLSPTFRPGAPSGQTVPPPLPKPPRSPSRSPSHSPNRSPCVPPAPDMALPRLGTQSTGPGRCLSPNLQAQEAPAPVTTSSSTSTLSSSPWSAQPTWKSDPGFRITVVTWNVGTAMPP-DDVTSLLHLG--------GGDDSDGADMIAIGLQEVNSMLNKRLKDALFTDQWSELFMDALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRIESYD--LHFVKFAIDSDQLHQLWEKDQLNMAKN-TWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKS------HRLQVTQHSYRSHMEYTVSDHKPVAAQFLLQFAFRDDMPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKHEDVDGN--TYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEPFQISLPSSELASSS-TDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSPGLARFPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSLSPSPQGHRGLEEGGLGP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RLT2-1", "uniprot_id": "A0A8M1RLT2_DANRE", "id": "A0A8M1RLT2-1", "name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A", "aln": "-------------------------------------------------------------------------------------------MEAEQQIQSESKSNDLASSTP----------PKAP------------------------------------------------------------------SEASPPAVPSAPARPRRPQRSPRVEG--------------------SIDVSEPKP---------------------------------------PESPKPSSHD-------------------EPNAEAQAQLR----------VHAPPAALKLSGHASVARSHISMRAASLPQAPSYKPP-----------STESVVHPQRALSVAGT-----------ADTQPQVAED--FRIHIVTWNVGSAMPP-EDITNLLGLN--------VGDGN--TDMYIIGLQEVNSMINKRLKDVLFTDQWSEVCMDALSPFGYVLATSQRMQGMLLLVFAKYFHLPFLRGIQTQTTRTGLGGIWGNKGGVSARMTVFGHSICFLNCHLPAHMENTEQRMEDFESILQQQQFDGQAATGVLDHDVVFWFGDLNFRIEDLE--MQVVKGAIDNNKLSVLWEKDQLNIAKD-SETVLEGFHEGPLKFPPTYKFDVGTDTYDTSGKKRMPAWTDRILWRLRPMAQVSNSTSKRSSLSGLTSGTRVSQHFYRSHMEYTVSDHKPVSSVFTLQFPYKVDMPLVTIFVEDEWREISDAVAKFKVAPNFARSSWDWIGIYKVGFKHHKDYVAYTWAKQEESDFLRQEHQVNFTEEELPKESGDFILGYYSNNTSSIVGITEPFQIQLPASAAAGLSPSDSSDFTSDDE------VKKPDSGDSSP------ETEDPVSSRLTEEQMAKPSR----------PHAR--PRHG--KHHAGSAVQPSDE-------------------------------PENSGKAAAEPEEP----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PHS8-1", "uniprot_id": "M9PHS8_DROME", "id": "M9PHS8-1", "name": "Inositol polyphosphate-related phosphatase domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQTEASKTPKIPDSEPDGSKGKGKQQLET---------------------------------------------------------YRVYVVTWNVGSRFPDNISLRHLLGLQDVTVDKDTKETNAHLPDIYALGLQEVNAQPQQQVLGLFKEDPWTHKAKELLRNYDYVAVKTEQMQGLLLSMFVRRQHVEHLQDIEAEFTRTGFGGIWGNKGAVSVRFTLYGCGLAFVVAHLTAHDHMMDERIEDYKQILENHHYHVKRYREIYDHDYVFWFGDLNFRLQGSDSSTEVRELVRDESQHEALIQRDQLYQVREKSQLAFQVLQERLPAFPPTFKFREGTSEYDLK---RRPAWTDRIMYAVQPLNRQPG------------MQLSIEQCSYKSHPLYTISDHKPVTSDFTIKLYPNVRAPGVVFSPLSLWKIGDENTVEYHKQAEFDEGSNDWIGIFPSEYASLADYVAYEYVNQAESPSS---SDSNHQPDPFETPSHHRRGRHHHRNRQRQRRHQEANAQELVRLDFADDVELRHGEQYLLIYFRSTGVRGVTSLAGVSGVFVAEKRHGSPHRTEYHVDXLAEALDIFIL--------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . .. . :. : :*: :******: :* .: ** * . .*: :******: :::: . : * *:. : * :.:* ..: :***::* :*.: *: .*:.:::: ****:** *****.**.*:: :* :.*: .**.** . ::* :::: **. :::. : *** **********::. : .. : . *..: * ::*** .:: : :: ::* *.**:** **. ** . * *******:: ::. .. : * *:** **:******:: * ::: . * * : . * .: ...:: . * ..* ****:: : ***** :.:: : : .. : : . . :: .: . *. .* *. . .. . * . .* :. : . ", "identical_positions": 121, "similar_positions": 159, "identity": "11.76%" }, { "cls_id": "homologset.agr.RGD:620542", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R9Q1-1", "uniprot_id": "M0R9Q1_RAT", "id": "M0R9Q1-1", "name": "RNA-binding protein 14", "aln": "MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGAVRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPALAIQSGDKTKKPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQPSVSLGAAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGVQPSASALSTYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASYNAQPSASYSAQSAPYAAQQAASYSSQPAAYVAQPAAAAAYASQPAAYAAQATTPMAGSYGAQPVVQTQLNSYGAQASMGLSGSYGAQSAAAATGSYGAAAAYGAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASYRGQPGSAYDGTGQPSAAYLSMSQGAVANANSTPPPYERTRLSPPRASYDDPYKKAVAMSKRYGSDRRLAELSDYRRLSESQLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRAAQMHSGYQRRM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C2Q3-1", "uniprot_id": "RBM14_MOUSE", "id": "Q8C2Q3-1", "name": "RNA-binding protein 14", "aln": "MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGAVRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPALAIQSGDKTKKPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQPSVSLGAAYRAQPSASLGVGYRTQPMAAQAASYRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGVQPSASALSTYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASYSAQPSASYSAQSAPYAAQQAASYSSQPAAYVAQPATAAAYASQPAAYAAQATTPMAGSYGAQPVVQTQLNSYGAQASIGLSGSYGAQSAAAATGSYGAAAAYGAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASYRGQPGSAYDGTGQPSAAYLSMSQGAVANANSTPPPYERTRLSPPRASYDDPYKKAVAMSKRYGSDRRLAELSDYRRLSESQLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRAAQMHSGYQRRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PK6-1", "uniprot_id": "RBM14_HUMAN", "id": "Q96PK6-1", "name": "RNA-binding protein 14", "aln": "MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSGDKTKKPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQPSVSLGAAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGAQPSASALSSYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASYNAQPSASYNAQSAPYAAQQAASYSSQPAAYVAQPATAAAYASQPAAYAAQATTPMAGSYGAQPVVQTQLNSYGAQASMGLSGSYGAQSAAAATGSYGAAAAYGAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASYRGQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYERTRLSPPRASYDDPYKKAVAMSKRYGSDRRLAELSDYRRLSESQLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRAAQMHSGYQRRM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************************:**********************************************************************************************************.**:***********************************************************************************************************:****************************************.********:*************************************************************************************.*******.**************************:*****************************************:*****************************************************************.****:**********************************************************************************************************************", "identical_positions": 657, "similar_positions": 12, "identity": "98.21%" }, { "cls_id": "homologset.agr.RGD:620543", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZV2-1", "uniprot_id": "DCBD2_RAT", "id": "Q91ZV2-1", "name": "Discoidin, CUB and LCCL domain-containing protein 2", "aln": "MASRAPLRAARSPQDPGGRAAPAATGRAPLPSAGWCPLPPGRNSSSRPR-----LLLLLLLLLPDAGAQKGDGCGHTVLGPESGTLTSINYPHTYPNSTVCKWEIRVKTGERIRIKFGDFDIEDSDYCHLNYLKIFNGIGVSRTEIGKYCGLGLQMNQSIESKGSEITVLFMSGIHASGRGFLASYSVIDKQDLITCLDTVSNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGIHAGVVSDVLGGQISVVISKGTPYYESSLANNVTSMVGYLSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHMGQENSWKPEKARLRKPGPPWAAFATDEHQWLQIDLNKEKKITGIVTTGSTLIEHNYYVSAYRVLYSDDGQKWTVYREPGAAQDKIFQGNKDYHKDVRNNFLPPIIARFIRVNPVQWQQKIAMKVELLGCQFTLKGRLPKLTQPPPPRNSNNLKNTTVHPKLG--RAPKFTQALQPRSRNDLPLLPAQTTATPDVKNTTVTPSVTKDVALAAVLVPVLVMALTTLILILVCAWHWRNRKKKAEGTYDLPHWDRAGWWKGVKQLLPAKSVEHEETPVRYSNSEVSHLSPREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEASYADLDPYNAPVQ-EVYHAYAEPLPVTGPEYATPIVMDMSGHSTASVGLPSTSTFRTAGNQPPALVGTYNTLLSRTDSCSSGQAQYDTPKGGKP-AAAPEELVYQVPQSTQEASGAGRDEKFDAFKETL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZV3-1", "uniprot_id": "DCBD2_MOUSE", "id": "Q91ZV3-1", "name": "Discoidin, CUB and LCCL domain-containing protein 2", "aln": "MASRAPLRAARSPQGPGGPAAPAATGRAALPSAGCCPLPPGRNSSSRPR-----LLLLLLLLLQDAGGQQGDGCGHTVLGPESGTLTSINYPHTYPNSTVCEWEIRVRTGERIRIKFGDFDIEDSDYCHLNYLKIFNGIGVSRTEIGKYCGLGLQMNQSIESKGSEVTVLFMSGTHAAGRGFLASYSVIDKEDLITCLDTVSNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGIHAGVVSNVLGGQISIVISKGTPYYESSLANNVTSTVGYLSASLFTFKTSGCYGTLGMESGVIADPQITASSALEWTDHMGQENSWTAEKARLRKPGPPWAAFATDEHQWLQIDLNKEKKITGIVTTGSTMIEHSYYVSAYRVLYSDDGQRWTVYREPGVDQDKIFQGNKDYHKDVRNNFLPPIIARFIRVNPVQWQQKIAMKVELLGCQFTLKGRLPKLT--PPPRNGNNLRNTTARPKLGKGRAPKFTQVLQPRSRNELPVQPAETTTTPDIKNTTVTPSVTKDVALAAVLVPVLVMALTTLILILVCAWHWRNRKKKTEGAYDLPHWDRAGWWKGMKQLLPAKSVDHEETPVRYSTSEVSHLSAREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPMQ-EVYHAYAEPLPVTGPEYATPIVMDMSGHPTASVGLPSTSTFKTAGTQPHALVGTYNTLLSRTDSCSSGQAQYDTPKGGKS-AATPEELVYQVPQSTQELSGAGRDEKFDAFKEIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PD2-1", "uniprot_id": "DCBD2_HUMAN", "id": "Q96PD2-1", "name": "Discoidin, CUB and LCCL domain-containing protein 2", "aln": "MASRAVVRARRCPQCPQVRAAAAAPAWAALPLS--RSLPPCSNSSSFSMPLFLLLLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVIDKQDLITCLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGVHAGVVSNTLGGQISVVISKGIPYYESSLANNVTSVVGHLSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQFIPKGRPPKLTQPPPPRNSNDLKNTTAPPKIAKGRAPKFTQPLQPRSSNEFPAQTEQTTASPDIRNTTVTPNVTKDVALAAVLVPVLVMVLTTLILILVCAWHWRNRKKKTEGTYDLPYWDRAGWWKGMKQFLPAKAVDHEETPVRYSSSEVNHLSPREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPGQ-EVYHAYAEPLPITGPEYATPIIMDMSGHPTTSVGQPSTSTFKATGNQPPPLVGTYNTLLSRTDSCSSAQAQYDTPKAGKPGLPAPDELVYQVPQSTQEVSGAGRDGECDVFKEIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UYK1-1", "uniprot_id": "A0A8N7UYK1_DANRE", "id": "A0A8N7UYK1-1", "name": "", "aln": "--MDASVMVGR------------GTGGAALFIL---------------------IVFIVLLGARSSRAQKGDGCGHTVLGVGSGSLASLGYPQSYPSQSVCEWEISVTAGHKVLVRIADLDIDTNN-CQVSYLRLYNGIGPGRTEIVKFCGSKEWKDVVIKSEGHQVTVQFMSGPHHNGRGLFLSYTNSQHTDLITCLEKGEHFSEAEFSKFCPAGCLIDFGEVSGTIPHGYRDSSPLCLAGIHAGVLSNTLGGQISVVSSKGIPHYESSLANNVTSVPGNLSPSLFTFKTSGCYGTLGLESGVVSDSQITASSEWEWGGHGKQPTVWGPTGARLKTPGRPWAAANSDTKEWIQVDLKKEKKITGITTTGSTLPEYQFYVSAYEVLYSHDGQQWKTYQEVGSDKNKIFQGNTHYLQEVRNNFIPPIEARFLRICPLQWHQRIALKMELLGCQPH-AARPRIFHPGPAP----------------------------PRRKSTTPPAQDRTTHTPNIRNSTMPPHSHDEVALVAVLVPVLVVVLTTPVLVMVCSWLWKNRKS-PEVTYDLPHWERTVWWKSMKQLLPSK-LDGEDCVRYSSTARVDHQRPR-------VEPAEYAQPLVTGNMASLGQRSTFKPEE------ADVPEYDAPIPPEHYHAYAEPLPASGTEYAMPIMIDRANHLSG-----GTLPFRGRG------------LVTQTDSSQSANSAYDTPKITSDQATPTEGQLYQVPQNTHNSPSQTID----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . * ... *.* :::::** .: .*:********** **:*:*:.**::**..:**:*** * *.:: :::.*:**: .: *:..**:::**** .**** *:** : *:*:* ::*: **** * ***:: **: :: ******:. .:* *.****:******: *.*:***************:**:****:*:.******:* *** *:*********** * **.***************:****::*.****** ** .* * . * . ***:.** **** :* :*:*:**:******** *****: *:.:*****.:***.***:*..*:* * ::******..* ::*****:*** ***:*: * **:*:**:*:****** .* : *.* ** . * .** :*:::*:*:.* .:***.********:.*** :*::**:* *:***. .* :****:*:*: ***.:**:**:* :: *: *.:.*.* .* .:.******** * :.:* ********* **: *::* * ********* :*.*** **::* :.* : .* .*: * *:::***..*.:: ***** . ...: :*****.*:: .. * ", "identical_positions": 351, "similar_positions": 188, "identity": "45.12%" }, { "cls_id": "homologset.agr.RGD:620544", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0H7-1", "uniprot_id": "BCL10_MOUSE", "id": "Q9Z0H7-1", "name": "B-cell lymphoma/leukemia 10", "aln": "MEAPAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPRGLDTLVESIRREKTQSFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFAAGATNNLSRCNSDESNLSEKQRASTVMYHPEGESSTAPFFSMASSLNLPVLEVGRTENSSFSSATLPRPGDPGAPPLPPDLRLEEGGSCGNSSEMFLPLRSRALSRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QYN5-1", "uniprot_id": "BCL10_RAT", "id": "Q9QYN5-1", "name": "B-cell lymphoma/leukemia 10", "aln": "MEAPAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFAAGATNNLSRSNSDESNFSEKQRPSTVIYHPEGESSTAPFFSTESSLNLPVLEVGRLENSSFSSASLPRPGDPGAPPLPPDLRLEEGGSCGNSSEMFLPLRSRALSRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95999-1", "uniprot_id": "BCL10_HUMAN", "id": "O95999-1", "name": "B-cell lymphoma/leukemia 10", "aln": "MEPTAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFPDGATNNLSRSNSDESNFSEKLRASTVMYHPEGESSTTPFFSTNSSLNLPVLEVGRTENTIFSSTTLPRPGDPGAPPLPPDLQLEEEGTCANSSEMFLPLRSRTVSRQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..************************************************************************:***************.********************************. ********.******:*** *.***:*********:**** ************ **: ***::****************:*** *:*.************::***", "identical_positions": 208, "similar_positions": 18, "identity": "89.27%" }, { "cls_id": "homologset.agr.RGD:620545", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZN7-1", "uniprot_id": "CHK1_RAT", "id": "Q91ZN7-1", "name": "Serine/threonine-protein kinase Chk1", "aln": "----------------------------------------------------------------------MAVPFVED---WDLVQTLGEGAYG------------------------EVQLAVNRITEEAVAVKIVDMKRAIDCPEN---IKKEICINKMLNHENVVKFYGHR--------------------------REGNIQYLFLEYCSGGELFDR-IEPDIGMPEQDAQRFFHQLMAGVVYLHGIG-ITHRDIKPENLLLDERDNLKISDFGLATVFRHN-NRERLLNKMCG------------------------TLPYVAPELLKRK-EFHAEPVDVWSCGIVLTAMLAGELP---------------WDQPSDSCQEYSDWKEKK--TYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLNRG----------------AKRPRATSGGMSESSSGFSKHIHSNLDFSPINSGSSEENVKFSSSQPEPRTG--------LSLWDTG--------PSNVDKLVQGISFSQPTCPDHMLVNSQLLGTPGSSQNPWQRLVKRMTRF-------FTKLDADKSYQCLKETFEKLG------------------YQWKKSCMNQVTVSTMDRRNNKLIFKINLVEMDEKIL-VDFRLSKGDGLEFKRHFLKIKG---------------------KLSDIVSSQKVWFPVT--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35280-1", "uniprot_id": "CHK1_MOUSE", "id": "O35280-1", "name": "Serine/threonine-protein kinase Chk1", "aln": "----------------------------------------------------------------------MAVPFVED---WDLVQTLGEGAYG------------------------EVQLAVNRITEEAVAVKIVDMKRAIDCPEN---IKKEICINKMLSHENVVKFYGHR--------------------------REGHIQYLFLEYCSGGELFDR-IEPDIGMPEQDAQRFFHQLMAGVVYLHGIG-ITHRDIKPENLLLDERDNLKISDFGLATVFRHN-NRERLLNKMCG------------------------TLPYVAPELLKRK-EFHAEPVDVWSCGIVLTAMLAGELP---------------WDQPSDSCQEYSDWKEKK--TYLNPWKKIDSAPLALLHKILVETPSARITIPDIKKDRWYNKPLNRG----------------AKRPRATSGGMSESSSGFSKHIHSNLDFSPVNNGSSEETVKFSSSQPEPRTG--------LSLWDTG--------PSNVDKLVQGISFSQPTCPEHMLVNSQLLGTPGSSQNPWQRLVKRMTRF-------FTKLDADKSYQCLKETFEKLG------------------YQWKKSCMNQVTVSTTDRRNNKLIFKINLVEMDEKIL-VDFRLSKGDGLEFKRHFLKIKG---------------------KLSDVVSSQKVWFPVT--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14757-1", "uniprot_id": "CHK1_HUMAN", "id": "O14757-1", "name": "Serine/threonine-protein kinase Chk1", "aln": "----------------------------------------------------------------------MAVPFVED---WDLVQTLGEGAYG------------------------EVQLAVNRVTEEAVAVKIVDMKRAVDCPEN---IKKEICINKMLNHENVVKFYGHR--------------------------REGNIQYLFLEYCSGGELFDR-IEPDIGMPEPDAQRFFHQLMAGVVYLHGIG-ITHRDIKPENLLLDERDNLKISDFGLATVFRYN-NRERLLNKMCG------------------------TLPYVAPELLKRR-EFHAEPVDVWSCGIVLTAMLAGELP---------------WDQPSDSCQEYSDWKEKK--TYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKG----------------AKRPRVTSGGVSESPSGFSKHIQSNLDFSPVNSASSEENVKYSSSQPEPRTG--------LSLWDTS--------PSYIDKLVQGISFSQPTCPDHMLLNSQLLGTPGSSQNPWQRLVKRMTRF-------FTKLDADKSYQCLKETCEKLG------------------YQWKKSCMNQVTISTTDRRNNKLIFKVNLLEMDDKIL-VDFRLSKGDGLEFKRHFLKIKG---------------------KLIDIVSSQKIWLPAT--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQA7-1", "uniprot_id": "A0A8M9PQA7_DANRE", "id": "A0A8M9PQA7-1", "name": "Serine/threonine-protein kinase CHK1", "aln": "----------------------------------------------------------------------MAVPFVKD---WDVVQTLGEGAYG------------------------EVRLLVNKKTEEAVAVKVVDMAKAKDCIEN---VKKEVCICKMLSHPNIVRFFGHR--------------------------SEGTTQYIFLEYCSGGELFDR-IEPDVGMPEKEAHRFFQQLIAGVEYLHSVG-ITHRDIKPENILLDDKDNLKISDFGLATMFRHR-GRERALNRLCG------------------------TLPYVAPELMSRS-SFNAQPADTWACGIVLTAMLAGELP---------------WDQPSENCQEYLDWLERK--TYLTPWKKIDAVPLSLLSKILLHNPEDRFTIPEIKKHRWFSRSFKSA----------------VQRQGITPAAKIQRAD------------SELRRKNSDDRAQISSSQPEPQG-----------LWEEK--------EVTVHTDVS-VSFSQPTCPDHMLLGTQLLGTPGASQSPWQRLVRRMTRF-------FTTENTEASCIALRDSCIALG------------------HTWKQSCNNQATVSTMDRRNNKLIFIVHFLEMEERIL-VDFRLSKGDGLEFKRIFLKLKQ---------------------KLSDIISNQKVLPLI---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61661-1", "uniprot_id": "CHK1_DROME", "id": "O61661-1", "name": "Serine/threonine-protein kinase grp", "aln": "---------------------------------------------------------MAATLTEAGTGPAATREFVEG---WTLAQTLGEGAYG------------------------EVKLLINRQTGEAVAMKMVDLKKHPDAANS---VRKEVCIQKMLQDKHILRFFGKR--------------------------SQGSVEYIFLEYAAGGELFDR-IEPDVGMPQHEAQRYFTQLLSGLNYLHQRG-IAHRDLKPENLLLDEHDNVKISDFGMATMFRCK-GKERLLDKRCG------------------------TLPYVAPEVLQK--AYHAQPADLWSCGVILVTMLAGELP---------------WDQPSTNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLRKLLATSPGTRLTLEKTLDHKWCNMQFADN----------------ERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYCSQPMPTMRSDDD--FNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQTQNASQNYFQRLVRRMTRF-------FVTTRWDDTIKRLVGTIERLGG-----------------YTCKFGDDGVVTVSTVDRNKLRLVFKAHIIEMDGKIL-VDCRLSKGCGLEFKRRFIKIKN---------------------ALEDIVLKGPTTWPIAIATNSVP-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VRE0-1", "uniprot_id": "Q9VRE0_DROME", "id": "Q9VRE0-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "aln": "MTLDVGGVARGLLTWDKQEHLVKLAILILAAVLSFATRLFSVLRFESVIHEFDPYFNYRTTRFLAEQGFYKFHNWFDDRAWYPLGRIIGGTIYPGLMLTSAALYRLMW-LLNVTIDIRNVCVFLAPFFSSLTTLVTYALTKEIHSTGAGLVAAALISIVPGYISRSVAGSYDNEGIAIFCMLFTYYLWIKAVKTGTIFWSAMSALAYFYMVSSWGGYVFLINLIPLHVLALMITGRFSHRIYIAYSTLYCVG-TILSMQISFVGFQPIQSSEHMLALGTFGLCQIH-AFVDYLRSRIPKDHFDLLFKTLVSSVLTVVFVVGTLLTLTGKVSPWTG-RFYSLLDPSYAKNHIPIIASVSEHQPTSWSSFYFDLQILVFLFPAGLYFCFSKLTDSN--IFIILYGVTSIYFAGVMVRLMLVLAPVMCVLSGIAISHLLAKYIKSVDAGSSSKQGVESKRQHKKLEQQTGGVKSEVAIGFVGVITLMLIVYTLHCTWVTSEAYSSPSIVLSARSHDGGRIIFDDFREAYYWLQMNTPEDARIMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMASSEEKA-------YEIMRELDVDYVLVIFGGLTGYSSDDINKFL--------WMVRIGGSTDRGAHIREKDYYAANGEFRVDKEGSPTL-LNCLMYKMCYYRFGQMYTEGGKAQGYDRVRAAEIGNKDF-ELDVMEEAYTTEHWLVRIYKVKDLPNRGV----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46978-1", "uniprot_id": "STT3A_MOUSE", "id": "P46978-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "aln": "--MTKLGFLR--LSYEKQDTLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEGFYKFHNWFDDRAWYPLGRIIGGTIYPGLMITSAAIYHVLH-FFHITIDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEGIAIFCMLLTYYMWIKAVKTGSIYWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCLG-TILSMQISFVGFQPVLSSEHMAAFGVFGLCQIH-AFVDYLRSKLNPQQFEVLFRSVISLVGFVLLTVGALLMLTGKISPWTG-RFYSLLDPSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVGLYYCFSNLSDAR--IFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGIGVSQVLSTYMKNLDISRPDKK-------SKKQQDSTYPIKNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMASTEEKA-------YEIMRELDVSYVLVIFGGLTGYSSDDINKFL--------WMVRIGGSTETGRHIKENDYYTPTGEFRVDREGSPVL-LNCLMYKMCYYRFGQVYTEAKRPPGFDRVRNAEIGNKDF-ELDVLEEAYTTEHWLVRIYKVKDLDNRGLSRT-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39007-1", "uniprot_id": "STT3_YEAST", "id": "P39007-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3", "aln": "-----MGSDRS-CVLSVFQTILKLVIFVAIFGAAISSRLFAVIKFESIIHEFDPWFNYRATKYLVNNSFYKFLNWFDDRTWYPLGRVTGGTLYPGLMTTSAFIWHALRNWLGLPIDIRNVCVLFAPLFSGVTAWATYEFTKEIKDASAGLLAAGFIAIVPGYISRSVAGSYDNEAIAITLLMVTFMFWIKAQKTGSIMHATCAALFYFYMVSAWGGYVFITNLIPLHVFLLILMGRYSSKLYSAYTTWYAIG-TVASMQIPFVGFLPIRSNDHMAALGVFGLIQIV-AFGDFVKGQISTAKFKVIMMVSLFLILVLGVVGLSALTYMGLIAPWTG-RFYSLWDTNYAKIHIPIIASVSEHQPVSWPAFFFDTHFLIWLFPAGVFLLFLDLKDEH--VFVIAYSVLCSYFAGVMVRLMLTLTPVICVSAAVALSKIFDIYLDFKTSDR------------KYAIKPAALLAKLIVSG---SFIFYLYLFVFHSTWVTRTAYSSPSVVLPSQTPDGKLALIDDFREAYYWLRMNSDEDSKVAAWWDYGYQIGGMADRTTLVDNNTWNNTHIAIVGKAMASPEEKS-------YEILKEHDVDYVLVIFGGLIGFGGDDINKFL--------WMIRISEGIWP-EEIKERDFYTAEGEYRVDARASETM-RNSLLYKMSYKDFPQLFNGG---QATDRVRQQMITPLDVPPLDYFDEVFTSENWMVRIYQLKKDDAQGRTLRDVGELTRSSTKTRRSIKRPELGLRV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38147-1", "uniprot_id": "CHK1_YEAST", "id": "P38147-1", "name": "Serine/threonine-protein kinase CHK1", "aln": "----------------------------------------------------------------MSLSQVSPLPHIKD---VVLGDTVGQGAFACVK---------------------NAHLQMDPSIILAVKFIHVPTCKKMGLSDKD-ITKEVVLQSKCSKHPNVLRLIDCN--------------------------VSKEYMWIILEMADGGDLFDK-IEPDVGVDSDVAQFYFQQLVSAINYLHVECGVAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRG------------------------SPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTP---------------WELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLNLLRKILQPDPNKRVTLKALKLHPWVLRRASFS-----------------GDDGLCNDPELLAKKLFSHLKVSLSNENYLKFTQDTNSNNRYISTQPIGNELAELEHDSMHFQTVSNTQRAFTSYDSNTNYNSGTGMTQEAKWTQFISYDIAALQFHSDENDCNELVKRHLQFNPNKLTKFYTLQPMDVLLPILEKALNLSQIRVKPDLFANFERLCELLGYDNVFPLIINIKTKSNGGYQLCGSISIIKIEEELKSVGFERKTGDPLEWRRLFKKIST---------------------ICRDIILIPN--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... : * : :. : . . : : : . . :: : . ** :* : * . : :: . : . : .. :: :* : . : : :: : ..: : * : : : :: ::: . . * : . : :. : : : . .. . . . : : : : ", "identical_positions": 8, "similar_positions": 73, "identity": "1.05%" }, { "cls_id": "homologset.agr.RGD:620546", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LEP2-1", "uniprot_id": "A0ABK0LEP2_RAT", "id": "A0ABK0LEP2-1", "name": "Nesprin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATSRASSRSHRDITNVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRGKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQS-LSSSASSVDSMVSTETASPPSKRKVATKVQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIRPELVDLEKVKNRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFLTQYPDIRGAGYDVQEN---------------------------DRDDRLILKEAKVWIEQFERDLTRAQMTESNLQDKYQSFKHFRVQYELKRKQVEHIIQPLQRDGKLTLDQALVKQCWERVSSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITIQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPMPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVELLLQSYISFIENSKFFEQYEVTYQVLKQTAEMYVKADGS-------VEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGDTVASLQAWLEDAEKMLSQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEIVSRDLKQQLLLLNGRWRELFMEVKQYARADEMDRMKKEYTDGTAALSGFAAEAHRKLSEPLEVSFMN-VKLLIQDLEDTEKRVPVMDAQYKMIAKKAHLIAKESPKEEANEMLTTMSRLKEQLSKVKECYSPLLYEAQQLSVPLEELETQITSFYDSLGKINEILAVLEHEAQSSALFKQKHQELLACQESCKKSLTFIEKGSQSVQKLVTSSQALKHWDHTKLQKQIADVHHAFQNMIKKTGDWKKHVEANSRLMKKFEESRAELEKVLRAAQEGLEEKGDP-EELLRKHTDFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIAVEKDRFSAAVEECRAELERETKLASQ-EGSEKIIKEHRVFFSDKGPHHLCEKRLRLIEELCVKLPVRDP----VRDTSGACHTALKELKASIDNTYMMLMDDPDKWTDYASRFSELSSWVSAKESWLKNIKDQPIDTGNHDEVKRVADEMRNDITKKGEILSWLKSRLKHLIDVSSENEAQKRGDELAELSSSFKALVALLSEVEKMLSNFGECVQYKEIVKSSLEGLMSGSEESKDEAETILDTENLFEAQQMLLRHQQKTKMISAKKRDLQQQMEQG--QQG--GQAGPGQEELRKLESTLTGLEQSRERQERRIQVSLRKWERFETNKETVVRYLFQTGSSHERFLSFSS-LESLSSELEQTKEFSKRTESIATQAEN---LVKEAAEMPLGPRNKRLLQQQAKSIKEQVKTLEDTLEEDIKTMEMVKTKWDHFGSNFETLSNWITEKE-NELSSLETSASAMEMQINQIKVTIQEIEGKIESVVGLEEAAQSFAQFIT-TGESARIKAKLTQIRRYWEELQEHARGLEGVILGQLSQQQKFEENLRKIQQSVSEFAERLAEPIKICSSAAETYKVLQEHMDLCQALESLSSTVTAFSASAQKVVNRESSTQETAALQQQYEEILHKAKERQKALEDLLAHWQRLEKGLSPFLTWLERCEAIARSPEKDIAADRV-KVDSELQLIQALQNEVVSQASLYSNLLQLKEALFSAASKEDVAMMKLQLEQLDERWGDLPQIISKRMLFLQSVLAEHRQFDELLFSFSVWIKQFLSELQMTSEINLRDHQVALTRHKDHATEIEKKRGEVKHLQGHLAQLRSLGRAEDLHPLQSKADDCFQLFEEASQVVERRKLALTQLAEFLQRHASVSTLLHQLRQTVEATKSMSKKQSDSLKKDLHDAIQDVKTLESSAIGLDGTLTKAQCHLKSGSPEQRTSCRATTDQLSLEVERIQNLLGTKQSEADALLVLKEAFQEQREELLRSIEDIEERTDRERLKEPTRQALQHRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVALAPEVDREINRLEATWDDTKRLIHENQGQCCGLIDLVREYQNLKSAVCKVLEDASHVVEMR-ATIKDQEDLKWAFSKHETSRNEMNSKQKELDSFTSKGKHLLSELKKIHSGDFSLVKTDMESTLDKWLDVSERIDENMDRLRVSLSTWDDVLSSRDEIEGWSNSSLPQLAENISDLNNSLRAEEFLKELESEVKNKALKLEELHSKINNLKELTKNPETPTELQFIEADLRQKLEHAKEITEEAKGTLKDFTAQSTQVERFVKDITAWLVNVEESLTRYAQT-----YTCEGLKKVKDIRKELQSQQNNIISTQEVLNSLCRKHHSVELESRGRAMTGLIKKHEATSQLCSQTQASIQDSLEKH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FSGSMKEFQEWFLGAKAAARESSNL--TGDSQVLEARLHDLQGVLDSFSDGQSKLDAVTQEGQTLYAHLPKQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCVSELGSFEDQHRKLNLWIHEMEERS-----------------------------------------------------------------------------------------------------NTENLGESRHHISEKKNEIHKVEMFLGELLAARESLDKLSQRGQLLSEESHGAGKGGRRS--------------------------------------------------------------------------------------------------------TQLLANYQNLLRVTKERLRGCQLALQEHEALEEAMQSMWSRVKDVKDRLACAESTLGDKETLEWRLSQIQDILLMKGEGEVKLNLAIGKGDQASKSSNKEGQQAIQDQLETLKKAWADAMSSAVHAQSTLESVIDQWNDYLEKKSQLEQWMESVDQKVEHPLQLQPGLKEKFSLLDHFQSIVSEAEDHTGALQQLAAKSRELYKKTQDESFKEAVQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EELRTQFQDILTVAKEKMRTVEDLVKDHLMYFDAVQEFTDWLHSAK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EELHRWSDTSGDSSATQKKLSKIKELMDSREIGAGRLSRVELLAPSVKQNTAASGCELLNSEMQALRADWRQWEDCLLQTQSSLEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVSEMALSEQEFSGQVARLEQALEQFSTLLKTWAQQLTLLEGKSTDEEIVECWHKEREILDALQKAEPMTEDLKSQLNELCRFSRDLSPYSGKVSGLIKEYNCLCLQASKGCQSKEQILQER----------------FQKASKSFQQWLVNAKITTAKCFDLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QNLSEVSSSLQKIQEFLSESETGQHKLNTMLSKGELLSSLLTKEKAQAVQAKVLTAKEDWKHFHANLHQKESALENLKIQMKDFEVSAEPVQNWLSKTKRLVQESSIRLY-DLPAKRREQQKLQSVLEEIQCYEPQLHRLKEKARQLWEGQAASKSFVHRVSQLSSQYLALSNVTKEKVSRLDRIVAEHNQFSLGVKELQDWMSDAVHMLDSYCLPTSDKSVLDGRMLKLEALLSVRQEKEIQIKMIMTRGEYVLQSTSPEGSHAVQQQLQALKEKWESLLSAAIRCKSQLEGALSKWTSYQDDVRQFSSWMDVVEVSLTELERQ------------HTELREKVTTLGKAKLLNEEVLSHGSLLETIQVKRAAMTEHYVTQLELQDLQERHQVLKEKAKETVTKLEKLVRLHQEYQRDLKAFENWLGQEQEKLDRSSVLEGDTNAHETTLRDLQELQVRCAEGQALLNSVLHTREDVILSGLP---QAEDRVLESLRQDWQVYQHRLAETRMQFNNVANKLRLMEQKFQEADEWLQRMEEKISVRNERQSSRSAKEIQLLQLKKWHEDLSAHRDEVEEVGSRAQEILDESRVSSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQCLEETESSLSSYSDWYGSTHKNFKNVATK-IDKVDEAMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAVKFLEGSEAEALRKEIHAHMEQLKNLTSAVRKEHVSLEKGVHLAKEFSEKYKVLTRWLAEYQEILLTPEEPKMELYEKKAQLSKYKSLQQMVLSHEPSMNSVQE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSEALLELVQDQTLKDK------------------------------------------------------------------------------------------------------------------IQKLQSDFQDLCSIGKERVFSLEAKVRDHEDYNTELQEVEKWLLQMSGRLAAPDLLETSSLETITQQLAHHKAMMEEIAGFEDRLDNLKAKGDTLIGQCPDHLQAKQKQSVQAHLQGTKDSYSAICSTAQRVYRSLEYELQKHVSRQDTLQQCQAWISAVQPDLKPSPQPPLS----RAEAVKQVKHFRALQEQARTYLDLLCSMCDLSNSSVKNTAKDIQQTEQLIEQRLVQAQNLTQGWEEIK-------------------NLKAELWIYLQDADQQLQN----------------------------------------------------------MKRRHAELEINIAQNMVLQVKDFIKQLQCKQASVSTITEKVDKLTKNQESPEHKEISHLNDQWQDLCLQSDKLCAQREQDLQRTSSYHDHMSIVEAFLEKFTTEWDNLARSNAESTAVHLEALKKLALALQEK-KFAIDDLKDHKQKLMEQLSLDDRELLREQTSHLEQRWFQLEDLVKRKIQVSVTNLEELNVVQSRFQELTEWAEEQQPNIVEALKQSPPPGTAHHLLTDHLAICSELEAKQVLLKSLMKDADRVMADLGLNERKVIQKVLSEAQKHVSCLNDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHE-RKIMFREYVCLLPDDVSKQVKTCKTAQASLKTYQN-EVTGLWTQGRELMKGITEQERNEVLGKLQELQSVYDTILQKCSHRLQELEKSLVSRKHFKEDFDKAQHWLKQADIVTFPEINLMNERVELHAQLDKYQSILEQSPEYENLLLTLQTTGQAMLPSLNEVDHSYLSEKLSAMPQQFNVIVALAKDKFYKIQEAILARKEYASLIELTTQSLGDLEDQFLKMRKMPSDLIVEESVSLQESCRTLLGEVVALGEAVNELNQKKESFRSTGQPWQPEKMLQLATLYHRLKRQAEQRISLLEDTTSAYREHAQMCQQLESQLEVVKREKAKVNEETLPAEEKLKVYHSLAGSLQDSEILLKRVAVHLEDLSPHLDPMAYEKGKGQVQTWQEELKQMMSEIGEMVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVCLDLRLQDIQEEIRKIQIHQEEILSSLRIMSALSQKEQEKFTKAKELISADLEHTLAELKELDGDVQEALRTRQATLTEIYSQCQRYYQVCQEANDWLEDAQEMLQLVGNGLDVESAEENLKSHMEFFKTEGQFH-SHMEELRGLVARLDPLIKPTGKEELAQKMASLEKRSQGVIQDSHTQRDLLQRCSVQWQEYQEAREGVIKLMNDVEKKLSEFVVTKISSSHEAEEKLSEHRALVSVVDSFHEKIVALEEKASQLEQTGNEANKATLSRSMTTVWQRGTRLRAVVQDQEMILEDAVDEWKALSAKIKENTEIINQLQGRLPGTSTEKTSKAELIALLESHDTFAMDLERQQLALGVLQQRALSMLQDGALPGP---KEEVPTLQEITALQDQCLNMQEKVKNHGKLLKQELQEREAVETCINSVKSWVQETKDYLGNPTLEVDTQVEELKSLLAEATSHRESIEK---IAEEQKNKYLGLYTILPSEISLQLAEVALDL-KIHDQIQEKVQEIEQGKAMSQEFSCQIQKVAKDLTTILTKLKAKTDNLVQAKADQKMLGEELDSCNSKLMELDTAVQTFSE--QHGQLGKPLAKKIGKLTELYQQTIRQAENRLSKLNQASSHLEEYSEMLESIQKWIEKAKVLVQGNIAWNSASQLREQYILHQTLLEESEEIDSDLETMAEKVQYLANVYCTGKLSQQVTQLGRETEELRQAIRVRLQSLQDAAKDMKKFEGELRNLQVALEQAQTILTSPEVGRLSLKEQLSHRQHLLSEM--------------------------------------------------------------------------------------------------------------------------------ESLKPKVQAVQLCQSALRIPEDVVTGLPLCHAALRLQEEASQLQHTAIQQYNIMQAGATAQRVQPAGPTL------EAVVQYEQYGQEMKHLQQLIEAAHREIEDKPVATGNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLT------------MKAKHATMLLTVTEVEGLAEGTEDVDPELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTEASVNQDIAYYQALSAEGLQTDAARIAPSAAASQELYEPGLEPSATAKLGDLQRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WETLKNVISEKQRTLYEALERQQKYQDSLQSVSTKMEAMEMKLSESLQPGR----------------------------------------------------------------------------------SPESQMAEHQALMDEVQMLQDEINGLQAS------LAEELVAE-SQESDPAEQLALQSTLTVLAER--------------------------------------------------MSTIRMKAAGKRQLLEEKLNDQLEEQRQEQALQRYRCEAEELDHWLLNTKATLDFAAGIPQEPMDMDAQLVDCQNMLVEIEQKVVALSQLSVRS-ENLLLEGKAHTKDEAEQLASKLRMLKGSLMELQR-----------------------------------------ALRDRQLNMQG----------------VTQEKEENDVDFTATQSPGVQEWLAQARNTRTHQRQSSLQQQKEFEQELAEQ--------------------------------------------------------------------------KSLLRSVASRGEEILIQHSTAEGSGGLGEKPDALSQELVMEGAKSFAEDQMRAKWESLHQEFSTKQKLLQNILEQEQEQMLYSSPNR--------------------------------------------------------------------------LLSGVLPLRGEAQTQDKSSVTSLLDGLSQAFGEVSSQSGGTDRQNIHLEQKLY------------------DGVSATSTWLDDVEEHLFVATALLPEETETCLFN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------QEALAKDIKEMSEEMDKNKNLFSQAFPEDSDNRDVIEDTLGCLLGRLSLLDSVVGQRCHQMK--------------------------------------ERLQQVLSFQNDLKVLFTSLADNNYIILQKLANMFKQPIVEQIQAIQQAEEGLRELDGGISELKQRGDKLQVDQ------------------------------------------SALQELSKLQDMYDELLVTISSRRSNLNQNLALKSQYDKALQDLVDLLDTG-----------------------------------------------------------QEKMAGDQKIIVSSKEEVQQLLSKHKEYFQGLESHLILTETLFRKIVDFAAMKETQLHSDRMAQASAVLKQAHKRGVELEYILEMWSHLDENLQELSRQLEVIENSIPSVGLVEESEDRLVERTSLYQHLKSSLNEYQPKLYQVLDDGKRLMMSISCSELESQLNQLGERWLGNTNKVSKELHRLETILKHWTRYQSEAADLIHWLESAKDKLAFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAKSSLKSSVTSTGNQLLRLKKVDTAALRAELSCMDSQWTDLLAGIPAVQEKLHQLQMDKLPSRHAISEVMSWISLMESVILKDEEDIRNAIGYKAIYEYLQKYKGFKIDLNCKQLTADFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQLLQGRVGEKIQMLEGLLESWSEYENSIQSLKAWFANQERKLEEHHQIGDQNSVQNALKDCQELEDLIKAKEKEVEKIEQNGLALIQNKREEVSCSVLN-TLWELRQTWASLERTVGQLKIQLTLVLGQWSIHKAAFEEISNHLMEARYSLSRFRLLTGS-SDAVQVQVDNLQNLHDDLEKQEGDLQKFGSLTNHLLKECHPPVAEALSSTLQEVNMRWNNLLEEIAKQLHSSKALLQLWQRYKDYSKQCASAVQRQEEQTNALLKAATSKDIADDEVAKWIQDCNDLLKGLGTVKDSLFILHELGEQLGQQVDDSAATTIQCEQLCFSQRLEALEQALCKQQAVLQAGVVDYETFAKSLEALEAWIVEAEGILQAQDPTHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELG----YRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEHKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIVDGQNLLEQGQVDDREEFSLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSHLPLSGLGSIPVPLQQVRTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELTDIQEKWKSASTHLEEQK---KKLAFLLKDWEKCEKGIADSLEKLRTFKKRLSQPLPDHHEELHAEQMRCKELENAVGRWTDDLAELVLLREALAAHLSAEDISILKERVELLQRQWEELCHQVSLRRQQVSERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAVAQENK-----IQLQQMGERLAKASHESKASEIQYKLSKVNDRWQHLLDLMAARVKKLKETLVAVQQLDKNMGSLRIWLAHMESELAKPIVYDSCNSEEIQKKLSEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLEISERTAAFPSSSGVLYTVAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDSACSLRQMAHGGNQRWDDLQKRVTSILRRLKHFISQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHSKIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLP--LPDDHDLS--DRELDLEDSMALSDLHWQDPSEDGMPSPQPSSNPSLSLPQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAS-RTLPSEDEEGEEDKEFYLRG-AVGLSDVVIPENPEAYVKLTENAIRNTSGDPTSLESQMRQLDKALDDSRFQIQQTANILRGKTP-TGPDLGTSYKGYMKLLGECSGSIDSVRRLEHKLAEEE-SFPGFTNPTS--TETQPAGVIDRWELLQAQAMSKELKMKQNLQKWQQFNSDLNNICAWLGETEEELDRLQHLALSTDIHTIKSHIKKLKELQKALDHRKAIILSINLCSSEFTQA--DSKESHDLQDRLSQMNRRWDRVCSLLEDWRGSLQDALMQCQDFHEMTHALLLLLENTDRRKNEIVPIDSTLDPETLQDHHTQLTQIKQELLKSQLRVASLQNMSRQLLVNAEGSDCLEAKEKVHVIGNRLKLLLKEVSRHIKDLEKLLGMSSSQQDLSSWSSADEVDTSGSVSPTSGRSTPNRQKSPRGKCSLSQPGPSVSSPKSRSTKGGSDSSLSETRPARAG---RDFLFRVLRAALPIQLLLLLLIGLTSRVPISEEDYSCALSNNFARSFHPMLRYTNGPPPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZWR6-1", "uniprot_id": "SYNE1_MOUSE", "id": "Q6ZWR6-1", "name": "Nesprin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATSRASSRSHRDITNVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRVKRIHAVANIGTALKFLEGRK-------IKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQS-LSSSASSVDSMVSTETASPPSKRKVAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFLTQYPDIHGAGCDGQEDDVVFVGFTNNIAL----------LLGFQRDDRLILKETKVWIEQFERDFTRAQMTESSLQDKYQAFKHFRVQYEMKRKQVEHIIQPLQRDGKLTLDQALVKQCWERVSSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITIQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYQTRSVNGIPMPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVELLLQSYISFIENSKFFEQYEVTYQILKQTADIYVKAEGS-------VEEAENVMKFMSEATAQWRNLSVEVRSVRSMLEEVISNWDRYGDTVASLQAWLEDAEKMLSQSEHAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEIVSRDLKQQLLLLNGRWRELFMEVKQYARADEMDRMKKEYIDVTTTLFGFATEAHRKLSEPLEVSFIN-VKLLIQDLEDLEKRVPVMDAQYKMIAKKAHLFAKESPQEEANEMLTTMSKLKEQLSKVKECCSPLLYEAQQLTVPLEELETQITSFYDSLGKINEILSVLEQEAQSSTLFKQKHQELLASQENCKKSLTLIEKGSQSVQKLVTSSQARKPWDHTKLQKQIADVHHAFQSMIKKTGDWKKHVEANSRLMKKFEESRAELEKVLRVAQEGLEEKGDP-EELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIAVEKDRFSAAVEECRAELEQETKLAPQ-EGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCGKLPVQDP----VRDTCGACHTALKELKASIDNTYTMLVDDPDKWKDYTSRFSEFSSWVSAKKACLKKIKDEPIDTGNHDEVKHMVDEIRNDITKKGESLSWLKSRLKYLIDISSENEAQKRGDELAELSSSFKALVALLSEVEKLLSNFGECVQYKEIVKSSLEGLISGPQESKEEAEMILDSKNLLEAQQLLLHHQQKTKMISAKKRDLQEQMEQA--QQG--GQAGPGQEELRKLESTLTGLEQSRERQERRIQVSLRKWERFETNKETVVRYLFQTGSSHERFLSFSS-LESLSSELEQTKEFSKRTESIATQAEN---LVKEAAELPLGPRNKRVLQRQAKSIKEQVTTLEDTLEEDIKTMEMVKSKWDHFGSNFETLSIWILEKE-NELSSLEASASAADVQISQIKVTIQEIESKIDSIVGLEEEAQSFAQFVT-TGESARIKAKLTQIRRYWEELQEHARGLEGTILGHLSQQQKFEENLRKIRQSVSEFAERLADPIKICSSAAETYKVLQEHMDLCQAVESLSSTVTMFSASAQKAVNRESCTQEAAALQQQYEEILHKAKEMQTALEDLLARWQRLEKGLSPFLTWLERCEAIASSPEKDISADRG-KVESELQLIQALQNEVVSQASLYSNLLQLKEALFSVASKEDVAVMKLQLEQLDERWGDLPQIISKRMHFLQSVLAEHKQFDELLFSFSVWIKQFLGELQRTSEINLRDHQVALTRHKDHAAEIEKKRGEITHLQGHLSQLRSLGRAQDLHPLQSKVDDCFQLFEEASQVVERRKLALAQLAEFLQSHACMSTLLYQLRQTVEATKSMSKKQSDSLKTDLHSAIQDVKTLESSAISLDGTLTKAQCHLKSASPEERTSCRATTDQLSLEVERIQNLLGTKQSEADALVALKEAFREQKEELLRSIEDIEERMDRERLKVPTRQALQHRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAFAPEVDREINGLEATWDDTRRQIHENQGQCCGLIDLVREYQSLKSTVCNVLEDASNVVVMR-ATIKDQGDLKWAFSKHETSRNEMNSKQKELDSFTSKGKHLLSELKKIHSGDFSLVKTDMESTLDKWLDVSERIEENMDMLRVSLSIWDDVLSRKDEIEGWSNSSLPKLAENISNLNNSLRAEELLKELESEVKIKALKLEDLHSKINNLKELTKNPETPTELQFIEADLRQKLEHAKEITEEARGTLKDFTAQRTQVERFVKDITAWLINVEESLTRCAQT-----ETCEGLKKAKDIRKELQSQQNSITSTQEELNSLCRKHHSVELESLGRAMTGLIKKHEATSQLCSQTQARIQDSLEKH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FSGSMKEFQEWFLGAKAAARESSNL--TGDSQILEARLHNLQGVLDSLSDGQSKLDVVTQEGQTLYAHLPKQIVSSIQEQITKANEEFQAFLKQCLKEKQALQDCVSELGSFEDQHRKLNLWIHEMEERL-----------------------------------------------------------------------------------------------------KTENLGESKHHISEKKNEVRKVEMFLGELLAARESLDKLSQRGQLLSEESHSAGKGGCRS--------------------------------------------------------------------------------------------------------TQLLTSYQSLLRVTKEKLRSCQLALKEHEALEEATQSMWARVKDVQDRLACAESTLGNKETLEGRLSQIQDILLMKGEGEVKLNLAIGKGDQALRSSNKEGQQAIQDQLEMLKKAWAEAMNSAVHAQSTLESVIDQWNDYLEKKSQLEQWMESVDQRLEHPLQLQPGLKEKFSLLDHFQSIVSEAEDHTGALQQLAAKSRELYQKTQDESFKEAGQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EELRTQFQDIMTVAKEKMRTVEDLVKDHLMYLDAVQEFADWLHSAK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EELHRWSDTSGDPSATQKKLLKIKELIDSREIGAGRLSRVESLAPAVKQNTAASGCELLNSEMQALRADWRQWEDCLFQTQSSLES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVSEMALSEQEFFGQVTQLEQALEQFCTLLKTWAQQLTLLEGKNSDEEILECWHKGREILDALQKAEPMTEDLKSQLNELCRFSRDLSPYSEKVSGLIKEYNCLCLQASKGCQNKEQILQER----------------FQKASRGFQQWLVNAKITTAKCFDLP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QNLSEVSSSLQKIQEFLSESENGQHKLNTMLFKGELLSSLLTEEKAQAVQAKVLTAKEEWKSFHANLHQKESALENLKIQMKDFEVSAELVQNWLSKTERLVQESSNRLY-DLPAKRREQQKLQSVLEEIQCYEPQLHRLKEKARQLWEGQAASKSFVHRVSQLSSQYLALSNVTKEKVSRLDRIIAEHNRFSQGVKELQDWMSDAVHMLDSYCLPTSDKSVLDSRMLKLEALLSVRQEKEIQMKMVVTRGEYVLQSTSLEGSAAVQQQLQAVKDMWESLLSAAIRCKSQLEGALSKWTSYQDDVRQFSSWMDSVEVSLTESEKQ------------HTELREKITALGKAKLLNEEVLSHSSLLETIEVKRAAMTEHYVTQLELQDLQERHQALKEKAKEAVTKLEKLVRLHQEYQRDLKAFESWLEQEQEKLDRCSVHEGDTNAHETMLRDLQELQVRCAEGQALLNSVLHTREDVIPSGLP---QAEDRVLESLRQDWQVYQHRLAEARMQLNNVVNKLRLMEQKFQQADEWLKRMEEKINFRSECQSSRSDKEIQLLQLKKWHEDLSAHRDEVEEVGTRAQGILDETHISSRMGCQATQLTSRYQALLLQVLEQIKFFEEELQCLEETESSLSSYSDWYGSTHKNFKNVATK-IDKVDESMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAMKFLAEHEAEALRKEIHTYMEQLKNLTSTVRKECMSLEKGLHLAKEFSDKYKVLAQWMAEYQEILCTPEEPKMELYEKKAQLSKYKSLQQMVLSHEPSVTSVQE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSEALLELVQDQSLKDK------------------------------------------------------------------------------------------------------------------IQKLQSDFQDLCSRAKERVFSLEAKVKDHEDYNTELQEVEKWLLQMSGRLVAPDLLEMSSLETITQQLAHHKAMMEEIAGFEDRLDNLKAKGDTLIGQCPEHLQAKQKQTVQAHLQGTKDSYSAICSTAQRVYRSLEYELQKHVSSQDTLQQCQAWISAVQPDLKPSPQPPLS----RAEAVKQVKHFRALQEQARTYLDLLCSMCDLSNSSVKNTAKDIQQTEQLIEQRLVQAQNLTQGWEEIK-------------------SLKAELWIYLQDADQQLQN----------------------------------------------------------MKRRHTELEINIAQNMVMQVKDFIKQLQCKQVSVSTIVEKVDKLTKNQESPEHKEITHLNDQWQDLCLQSDKLCAQREQDLQRTSSYHDHMRVVEAFLEKFTTEWDSLARSNAESTAIHLEALKKLALALQEE-MYAIDDLKDCKQKLIEQLGLDDRELVREQTSHLEQRWFQLQDLVKRKIQVSVTNLEELNVIQSRFQELMEWAEEQQPNIVEALKQSPPPGMAQHLLMDHLAICSELEAKQVLLKSLMKDADRVMADLGLNERKVIQKALSEAQKHVSCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHE-RKIVFREYICLLPDDVSKQVKTCKTAQASLKTYQN-EVTGLCAQGRELMKGITKQEQEEVLGKLQELQTVYDTVLQKCSHRLQELEKSLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNEKTELHAQLDKYQSILEQSPEYENLLLTLQTTGQAMLPSLNEVDHSYLSEKLSALPQQFNVIVALAKDKFYKTQEAILARKEYTSLIELTTQSLGDLEDQFLKMRKMPSDLIVEESVSLQQSCSALLGEVVALGEAVNELNQKKESFRSTGQPWQPEKMLQLATLYHRLKRQAEQRVSFLEDTTSVYKEHAQMCRQLESQLEVVKREQAKVNEETLPAEEKLKVYHSLAGSLQDSGILLKRVATHLEDLSPHLDPTAYEKAKSQVQSWQEELKQMTSDVGELVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVCLDLSLQDIQEEIRKIQIHQEEVLSSLRIMSALSHKEQEKFTKAKELISADLEHTLAELQELDGDVQEALRTRQATLTEIYSRCQRYYQVFQAANDWLDDAQEMLQLAGNGLDVESAEENLRSHMEFFKTEGQFH-SNMEELRGLVARLDPLIKATGKEELAQKMASLEKRSQGIIQESHTQRDLLQRCMVQWQEYQKAREGVIELMNDAEKKLSEFAVLKTSSIHEAEEKLSKHKALVSVVDSFHEKIVALEEKASQLEQTGNDTSKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWKRLSAKVKETTEVINQLQGRLPGSSTEKASKAELMTLLESHDTYLMDLESQQLTLGVLQQRALSMLQDRAFPGT---EEEVPILRAITALQDQCLNMQEKVKNHGKLVKQELQEREAVETRINSVKSWVQETKDYLGNPTIEIDTQLEELKRLLAEATSHQESIEK---IAEEQKNKYLGLYTVLPSEISLQLAEVALDL-KIHDQIQEKVQEIEEGKAMSQEFSCKIQKVTKDLTTILTKLKAKTDDLVHAKAEHKMLGEELDGCNSKLMELDAAIQTFSE--RHSQLGQPLAKKIGKLTELHQQTIRQAENRLSKLNQALSHMEEYNEMLETVRKWIEKAKVLVHGNIAWNSASQLQEQYILHQTLLEESGEIDSDLEAMAEKVQHLANVYCTGKLSQQVTQFGREMEELRQAIRVRLRNLQDAAKDMKKFEGELRNLQVALEQAQTILTSPEVGRRSLKEQLCHRQHLLSEM--------------------------------------------------------------------------------------------------------------------------------ESLKPKMQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASQLQHTAIQQCNIMQAKKHSLIFPPK----------EAVVQYEQYKQEMKHLQQLIEEAHREIEDKPVATSNIQELQAQISLHEELAQKIKGYQEQIDSLNSKCKMLT------------MKAKHATMLLTVTEVEGLAEGTEDLDRELHPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTEAAVNQDIAYYQALSAEGLQTDAARIPPSAAVSQELYEPGLEPSATAKLGDLQRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WETLKNVISEKQRTLYEVLERQQKYQDSLQSISTKMEAMEMKLGESLEPSR----------------------------------------------------------------------------------SPESQMAEHQALMDEVQMLQDEINGLQVS------LAEELVAE-SQESDPAEQLALQSTLTVLAER--------------------------------------------------MSTIRMKAAGKRQLLEEKLSDQLEEQRQEQALQRYRCEADELDHWLLNTKATLDVALGTSQEPMDMDAQLVDCQNMLVEIEQKVVALSQLSVHN-ENLLLEGKAHTKEEAEQLAVKLRLLKGSLGELQR-----------------------------------------ALHDRQLDMQG----------------VTQEKEENDVDFTDTQSPGVQEWLAQARTTRTHQRQSSLQQQKEFEQELAEQ--------------------------------------------------------------------------KSLLRSVASRGEEILTQHSTAEGSGGLGEKPDVLSQELG------IAEDQMRVKWESLHQEFSAKQKLLQNILEQEQEQVLYSSPNR--------------------------------------------------------------------------LLSGVLPFRGEAQTQDKTSVTSLLDGLSQAFGEASSQSGGTDRQSIHLEQKLY------------------DGVSATSTWLNDVEERLFVATAPLPEETEACLFN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------QEALAKDIKEMSEEMDKNKNLFSQAFPEDSDNRDVIEDTLGCLLGRLSLLDSVVDQRCHQMK--------------------------------------ERLQQILRFQNDLKVLFTSLADSKYIILQKLANVFEQPIVEQMQAIQQAEEGLRDLEGGISELKRWADKLQVEQ------------------------------------------SAVQELSKLQDMYDELLMTVSSRRSSLHQNLALKSQYDKALQDLVDLLDTG-----------------------------------------------------------QEKMTGDQKIIVCSKEEIQQLLGKHKEYFQGLESHMILTEILFRKIVGFAAVKETQFHTDCMAQASAVLKQAHKRGVELEYILEMWSHLDENRQELSRQLEVIENSIPSVGLVEESEDRLVERTNLYQHLKSSLNEYQPKLYQALDDGKRLLMSVSCSELESQLNQLGEHWLSNTNKVSKELHRLETILKHWTRYQSEAAALNHWLQCAKDRLAFWTQQSVTVPQELEMVRDHLSAFLEFSKEVDAKSALKSSVTSTGNQLLRLKKVDTAALRAELSRMDSQWTDLLTGIPVVQEKLHQLQMDKLPSRHAISEVMSWISLMESVILKDEEDIRNAIGYKAIHEYLQKYKGFKIDLNCKQLTADFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQLLQGRVGEKIQMLEGLLESWSEYENSVQSLKAWFANQERKLKEQHLLGDRNSVENALKDCQELEDLIKAKEKEVEKIEQNGLALIQNKREEVSGSVMS-TLQELRQTWISLDRTVEQLKIQLTSALGQWSNHKAACDEINGHLMEARYSLSRFRLLTGS-SEAVQVQVDNLQNLHDELEKQEGGLQKFGSITNQLLKECHPPVAETLSSTLQEVNMRWNNLLEEIAEQLHSSKALLQLWQRYKDYSKQCASAIQRQEEQTSVLLKAATNKDIADDEVTKWIQDCNDLLKGLETVKDSLFILRELGEQLGQQVDVSAAAAIQCEQLCFSQRLGALEQALCKQQAVLQAGVVDYETFAKSLEALEVWMVEAEGILQGQDPTHSSDLSTIQERMEELKGQMLKFSSLAPDLDRLNELG----YRLPLNDKEIKRMQNLNRHWSLTSSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEHKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIVDGQNLLEQGQVDDREEFSLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLAEVSHLPLSGLGNIPVPLQQVRMLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELTDIQEKWKAASMHLEEQK---KKLAFLLKDWEKCERGIANSLEKLRMFKKRLSQPLPDHHEELHAEQMRCKELENAVGRWTDDLTELMLVRDALAVYLSAEDISMLKERVELLQRQWEELCHQVSLRRQQVSERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAVAQENK-----IQLQEMGERLAKASHESKASEIQYKLSRVKDRWQHLLDLMAARVKKLKETLVAVQQLDKNMGSLRTWLAHMESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLEVSERTAAFPSSSGVLYTVAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDSACSLRQMVHGGNQRWDDLQKRVTSILRRLKHFISQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPVRLPDDHDLS--DRELDLEDSTALSDLRWQDPSADGMPSPQPSSNPSLSLPQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAS-RTLPSEDEEGEEDKEFYLRG-AVGLS-----------------------GDPSSLESQMRQLDKALDDSRFQIQQTANILRSKTP-TGPDLDTSYKGYMKLLGECSGSIDSVRRLEHKLAEEE-SFPGFVNLNS--TETQTAGVIDRWELLQAQAMSKELRMKQNLQKWQQFNSDLNNIWAWLGETEEELDRLQHLALSTDIHTIESHIKKLKELQKAVDHRKAIILSINLCSSEFTQA--DSKESHDLQDRLSQMNGRWDRVCSLLEDWRGLLQDALMQCQEFHEMSHALLLMLENIDRRKNEIVPIDSTLDPETLQDHHKQLMQIKQELLKSQLRVASLQDMSRQLLVNAEGSDCLEAKEKVHVIGNRLKLLLKEVSHHIKDLEKLLDMSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKSPRGKCSLSQPGPSVSSPKSRSTRDGSDSSRSDPRPERVG---RAFLFRILRAALPFQLLLLLLIGLTCLVPMSEKDYSCALSNNFARSFHPMLRYTNGPPPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NF91-1", "uniprot_id": "SYNE1_HUMAN", "id": "Q8NF91-1", "name": "Nesprin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRK-------IKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQS-LSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANS----------VQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGS-------VEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMN-VKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDP-EELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQ-EGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDP----VRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQA--QQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSS-LESLSSELEQTKEFSKRTESIAVQAEN---LVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKE-KELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQFVT-TGESARIKAKLTQIRRYGEELREHAQCLEGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADRV-KVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDLPQIINKRINFLQSVVAEHQQFDELLLSFSVWIKLFLSELQTTSEISIMDHQVALTRHKDHAAEVESKKGELQSLQGHLAKLGSLGRAEDLHLLQGKAEDCFQLFEEASQVVERRQLALSHLAEFLQSHASLSGILRQLRQTVEATNSMNKNESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSEQRTSCRATADQLCGEVERIQNLLGTKQSEADALAVLKKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAFAPEVDREINRLEVTWDDTKRLIHENQGQCCGLIDLMREYQNLKSAVSKVLENASSVIVTR-TTIKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGKHLLSELKKIHSSDFSLVKTDMESTVDKWLDVSEKLEENMDRLRVSLSIWDDVLSTRDEIEGWSNNCVPQMAENISNLDNHLRAEELLKEFESEVKNKALRLEELHSKVNDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITTWFTKVEESLMNCAQN-----ETCEALKKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELESLGRAMTGLIKKHEAVSQLCSKTQASLQESLEKH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FSESMQEFQEWFLGAKAAAKESSDR--TGDSKVLEAKLHDLQNILDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERF-----------------------------------------------------------------------------------------------------NTENLGESKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEGHGAGQEGRLC--------------------------------------------------------------------------------------------------------SQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFWVKAIQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAEDHTRALHRLIAKSRELYEKTEDESFKDTAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EELHRWSDMSGDSSATQKKLSKIKELIDSREIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQTQSCLEN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQILQQR----------------FRKAFRDFQQWLVNAKITTAKCFDIP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QNISEVSTSLQKIQEFLSESENGQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLY-DLPAKRREQQKLQSVLEEIHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCHPTSDKSVLDSRTLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPEGIPTIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDGVRQFSGWMDSMEANLNESERQ------------HAELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKGAGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDQYSVLEGDAHTHETTLRDLQELQVHCAEGQALLNSVLHTREDVIPSGIP---QAEDRALESLRQDWQAYQHRLSETRTQFNNVVNKLRLMEQKFQQVDEWLKTAEEKVSPRTRRQSNRATKEIQLHQMKKWHEEVTAYRDEVEEVGARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSDWYGSTHKNFKNVATK-IDKVDTVMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAVKYLEEGEAERLRKEIHDHMEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVRE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGEALLELVQDVTLKDK------------------------------------------------------------------------------------------------------------------IDQLQSDYQDLCSIGKEHVFSLEAKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLLETSSLETITQQLAHHKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGTKDSYSAICSTAQRMYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDLEPSPQPPLS----RAEAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKLVQAQNLTQGWEEIK-------------------HLKSELWIYLQDADQQLQN----------------------------------------------------------MKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQER-KYAIEDLKDQKQKMIEHLNLDDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHE-RKIMFREHICLLPDDVSKQVKTCKSAQASLKTYQN-EVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQKCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNILEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQEAILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDPLAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLAELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESAEENLKSHMEFFSTEDQFH-SNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRDSGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKALVSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTP---GEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEK---MAEEQKEKYLGLYTILPSELSLQLAEVALDL-KIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLE--QNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEM--------------------------------------------------------------------------------------------------------------------------------ESLKPKVQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQ---------------------EAVVQYEQYEQEMKHLQQLIEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLT------------MKAKHATMLLTVTEVEGLAEGTEDLDGELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQEFYEPGLEPSATAKLGDLQRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGR----------------------------------------------------------------------------------SPESQMAEHQALMDEILMLQDEINELQSS------LAEELVSE-SCEADPAEQLALQSTLTVLAER--------------------------------------------------MSTIRMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLLSTKATLDTALSPPKEPMDMEAQLMDCQNMLVEIEQKVVALSELSVHN-ENLLLEGKAHTKDEAEQLAGKLRRLKGSLLELQR-----------------------------------------ALHDKQLNMQG----------------TAQEKEESDVDLTATQSPGVQEWLAQARTTWTQQRQSSLQQQKELEQELAEQ--------------------------------------------------------------------------KSLLRSVASRGEEILIQHSAAETSGDAGEKPDVLSQELGMEGEKSSAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNR--------------------------------------------------------------------------LLSGVPLYKGDVPTQDKSAVTSLLDGLNQAFEEVSSQSGGAKRQSIHLEQKLY------------------DGVSATSTWLDDVEERLFVATALLPEETETCLFN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------QEILAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMK--------------------------------------ERLQQILNFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEDGLKEFDAGIIELKRRGDKLQVEQ------------------------------------------PSMQELSKLQDMYDELMMIIGSRRSGLNQNLTLKSQYERALQDLADLLETG-----------------------------------------------------------QEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVVESSIPSVGLVEENEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQLNQLGECWLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLLRLKKVDTATLRSELSRIDSQWTDLLTNIPAVQEKLHQLQMDKLPSRHAISEVMSWISLMENVIQKDEDNIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNKKEDVSSIVMS-TLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSLSRFRLLTGS-LEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQCASTVQQQEDRTNELLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSLFFLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLEALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELG----YRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQK---KKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENK-----IQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLP-LPDDEHDLS--DRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRG-AVGLS-----------------------GDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTP-TGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHS--TETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQA--DSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSG---RGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1N5-1", "uniprot_id": "A0A8M6Z1N5_DANRE", "id": "A0A8M6Z1N5-1", "name": "Nesprin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASLSPFGRSSKDIMNLMQKLQDEQESVQKRTFTKWINSHLAKHKPPFEVNDLFEDIKDGVKLLALLEVLSGQRLPCEQGRQLKRIHWVSNIGTALKFLEGRK-------IKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPALQA-LSSSASSVDSMASSETGSPPMKRKVVTKFQGNAKRALLRWVQNTATKRLGIEVKDFGASWRSGVAFHSVIHAIRPELVDMDVVRKRSNRENLEEAFSVAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDPHQSETDGQQEELVRSIPTFALSIPALQYDPQDIELMLEREERKVLREVKIWLDQLERDVLRAQGSEESLTDKYQAFKSFRVQYEMRKKQIESLLQPVHRDGKLSVDQAVVKQSWDHVSVRLLDWHIHLDKSLPGPLGVIGAWLHRAELSLREDVPIQQAHEETANIIHRKLEQHKEVLKNLEGHRQTFQQIHRDRSVNGVPVPPEQLQDMAERFNFVTTSSHVHLIKFEFWEMKYRLMAFLMLAESKLKSWIIKYGRRDSVELLLQNYIVFIEGHKFFEQYETTFRTLKQAADTYLKSGTSDGKITKRAEEVEGVNKFLSDATAQWKNLSVEVRSVRSMLEEVICNWEKYSSTVASLQAWLEDAEKMLNQSESDKREFFRNLPHWIQQHMDMNDAGNFLIETCDETVSRELKQQLLLLNGRWRELFVKVKHYARADEVDKLRKDYDDGIEALKAFIDTANERMNTPVQVSFLN-IRTYLQDVEDIKHKVPSMEAAYKTATRNAQQLTKDLSEDEIAHMLNNMTNIKDELSKIRERALPLLRDSQAMLPPLEEMEKNITGFYQSLEKASRITSSRDSEAPG--DFTQKCQELVTYQQSCKKCLSVIDKNHQVILKSLDTSKNLKHLDTSLLERRITELQASSQGMVKETTEWKQHVEANSSLMKRFEESRVELEKVLKIARSSMTERGNP-EDLLKKHTEFFGQLDQRVLNAFLKACDELTDILPEQEQQNLQETVRKLHKQWKDVQTEFPYHLLHLKVDLEKSRLMTSLQECQAELARENRSLPS-VGSERLIKEHRMFFKEKGPQALCEKRLQHMDELCLKLPESQQ----AQQTLVIARTAFAEVKEEIDSTHQRLMQHPDKWKEFNTRFSELSAWVTSKESQLRLLRNRAGDPSKFGQVKSTIESLRNDAELQEGNVSWLKNRLAALIEICTESDAQRQGAALSKLSNDFKGLLISLSESEKVVLAVSDCVQFREEVKTTLEELTQGQKELQSDNSKILDSESVREAQQLLLLHQQQLKRLRLKRKDMQEQINRGKQLQIEEGLEESLQDDLQKLESTLKKMDENTESQEKNLEVTLSAWQEFDAQQASVREFVGKVRSVTEREMNFSS-PESLSSELEQTKDLLKQCETEVRQVNT---LLKRATEIQLGPKNQSLLQDQARALSEQVDKVEKGLKRDVKTLEGMKSQWDLFGSEFEAFSSWIMERE-REMDALKSSSIPLDQQICTVQTIRDGLQERSEVLSNLEEKSQSLVQFVS-SGESARIKARLTQIGRYWEELKESVDHLSGQLEESSSHQTKFNSNLQQVQSEVEEIQKKLDNPVTSCISSSETYKTLQSHMDVFQSLEKLKATLLSLSAGARRLSEREKAERAVAALQQNYEQCLKQAKEKQNQTESLLSHWQKYEKDWSALKSCLERCEAACGPDSQSLPVDKL-KLDGELLELKHLQTELESLEVVYNRLGAQTPSLYTTASDERVKTLKEDHQQLEKRWMCQTTAIPHRIQVLQQHLSQVDQFDQALQKFFKWGESFLSSLHSSSHTDITDLQPSTNDIKEKREALLKQSIVRQNLQQQTKTLCDVCEPAEVQHLQGRWESSLQPYLEAHQLVELRGESLEKLEAFLHTHSVAAGVLQGLRQTVESAGSWDKSRVEELQRELEAIVPDISRLETLAVNLDGNLCKSHLHLMSGK-ETRSSCRSLADSLSAELDAVRNLLGSKQSEAEALGALWSSFRQRKEQLLKTVEDIEEKADQQGLKEPNVLTLQQRLRFFNQLEDELQSHQHEEQWLRDKGQQLAHRDAELGSEVLREINLLQTTWEDTKKLITERQEQSSALVDLMKDYQTLKSSINSILESADAIADIK-SVLKDQEDTRRSLLKHEAVKADMASHQDVLDRFSSKGKKLLSELNKIPDCDTQIVKTEIDATVDQWLDVSEKIEDNLESLKRSSALWVEIYDINGEIESWSNSSVMDLTDGLNNFNDSQKTAHKLSEVKVDVGLKEKKIDALQEKVSEMKQLCGGQDVPAKLQVMETDLRRKLNSIEELCDQAKNNLQDFCCQKKQLEDFLSQMSEWLMSVERSLVDSPCG-----TAPEEICRVKEIQKELQNQQASIDSARESLNTLCRKYPSEELAGLGSSLTDLIKKYETVNQICVKRLGSMQHGLQQH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FNDLVKEFHTWLSGQKDIVRECADH--SGDMSVVERKLQKLKGALERVEDGDDRLTLVCTEGEKLLLHLPKASAGQVQQSLSSIQQDWDSYVEQCRQNQQNLEDSASLLSGFDGRLQRLSRWLERMDVKM-----------------------------------------------------------------------------------------------------STELP--EGRHGDQERVTLERVEEFQHEVLKERDSFEGLCQEAQALSEGGHGSGSEVRAS--------------------------------------------------------------------------------------------------------AQLQHQHQSLLKAARERLRVCQLSMQEQQNFQETLQSTWLWLSSAQERLTALNSTGGNKETLEKRLALVQDILLMKGEGEVKLNMTVGKGEQVLKNCSRDKQEVIRSQLKSLKDSWANILMTAMSCHSRLEWTVAQWSSFQESKAQLQQWLEMVEQEAGVALPQQPGLKEKAALLERLRVIQADVEVHSTALSRLNEKATELYEKTGDQAFAERPK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDFNTQFTNITAVIKSKVQQMEEIVKEHEQYMESVRDLNDWLTSAK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EELQRWSDMSGDAASVQRKLSKVRGLLDSRKQGRERLTRVQSCGAATRDHTSTVGCEVLEREEAGLLSAWEQWERGAKHVCSGLEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLAQMANSEQEFNSLAAQLEQDLQEFSSKLQEWRIKLQQVEEMSAGEEAVQGWQIAKDTLEALQNVEPMSDNLKCQLNDLCRFSRDLGAQSERVSALIKEYNSLSLQASRECQGKEKLLEQR----------------FRAAFRDFQQWLVNAKINTAKCFDVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QNLAEASSSLQKIQEFLSDREQGQGKLNTVAASGELLMSIAAKDRVESVRAKINSAREDWKTLMTNLHQRENALQNLQAQMRDFETSVEPLQDWLNDTEEAVQESSSRLQ-DLTAKKQELHRLQSLLEELASKEPQLLRLREKAQQLWDGHTAGKGFVHRVSQLSAQYLALSNLTKEKASRIERVVSEHQLFSQGLKELQNWVSDTSHMLQTYCTPTADKNVLDSRMIKLEALLTARQEKEIQLKMLLTRGESVQRNTSADGVPLVRQQIEDLKDSWDGLLSASIQCKSQLEGALSQWTSYQEDVRQFVSWMETVEETLSSADKQ------------CSEMRDKTTNLGKAKLLLEDVLSHNSVLDVISMKGSNMAEHYVTQLEIQDLQERYNIVKDKAQCAVAKAEELVSAHQEYQHSLHEFKDWLDQQQERLSCYTQLEGDTETLEDTLRKLQELQVHCTEGQALLNTLLVSREQVIPWGVP---QLEDRCLEGVQQEWSSYQSRLTDTRSQLNSALAKLRQIEQKFQRLDNWLKGMESKGQLRTGRRSDRATKEAQLQLLKGWHEEVLVYQEEIEGLSVLAQQVLEETPISSRVSTRATQLTSRYHALLLHLLDTIKQLKEEVSCIEESQSVFCTFSDWLSTAQKNFSSVTTTNIDVVDRAAMEKKMKKLEALQGDMELGHTFLKTMREKTDRAMMFLEEPEAEQLKEEVDSRLSQLETLIRALRSEISATEKSIQLSKDFLDKYKTQTQWLSETKSLLASPVEPKAELYQKKAQLAKYKTIQQTIQSHESAVKSVIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGDALLETIRDPSISEN------------------------------------------------------------------------------------------------------------------IGKLKTDYQDLCADAKVHVQSLTESVREHEDYNSELQEVEKWLLQMSGRLVTSDSMQSGNLEMATQQLARHKAIMEEIAGFEERLSSLKDKGDHLVSSCTEQVQAKISQQIQAHQQGTRDSYSAICSTAQRVYQSLDRELQKHVSHQDTLQQCQTWLSSVKEEIQMQPQTPYG----LQEALKQVKHFRALQEQASTYLDLVCSVCDLSDESVRATAAKIQQTKTMIEERMSTSQELSDSWREIK-------------------EQKQELSTLFQDMEQQLQS----------------------------------------------------------LSRRPAELETKIAQNMLDQAREFGQQLQNRQSTLTKMTELVSKLTEGKESPEHTEIGRLSHAWLELCHQANKLQTQREEDLQRTKEYHDCISAMEALFEQVSKEWDNLARTDAESSSDHLEALRKLSVVLKDK-KSTLEDLKEQKQKVMYHLNLDDKELVKEQIGHFEQRWAHLESLIERKIQDSILTLEDMGQVEACLREAREWAEEQQPTLSEAMKMSPPPELAQSFLFDHLSICSELEAKQLLLAQAMGDADRVLAHLGLNERQRLQQLISETQAEVECLSVKVAQRRKHLSKAFTERTQFLLAVNQAITWVQQNE-KKAQAEEYIALLPDDLSKQVRTCRNIQSSLRAYQS-ELTSLWSQGRDLMKDASEEEKTEMLHKLQELQSIFEVALQKCSQRLQDLEKVLVTRKYFKADLEKICQWLKQADIVTFPEINLMNGDAELCSQLTKYQQILDQAMEFENLLLTVQRTGQEILPTLNEVDHCYLDEKLIALPQQYNNILGLAKEKQEKIQQAILARQEYASFIDVTHKALKELEEQFHSLGTQPIGLKTEEVVSLQADYKALLEELTNLGQAVGELNQKKEGFRSTGQPWMPEEMTQLVSLYNGLKRLIEQRVEHLDDTLESFEDHQAMAMQVDSELKATKEQLVKVNAETQSAEERLKNYHALAASLQGASSHLTRLMEQMDNLVSHMDTAAHEVSKQRVTSWQEELRSLQSSVGELIVECENRFVQSKDFETEVNRTLTWLQQIKDELGSEVVVDVKVEKVQEEIRKQQIMQEEVQSRLRIVAALSTREKQKYTSANELVPAHVDSSLQEMAKLEADVQRALSSKQITLEQALVLCQKYHSRMQAACEWLEDAVGFLQQASLGVDVENYEECLRQQEDIMATEQEFL-GVLEELESLPPQLENLVNPTAKEQLRLSVESAQQRGVEVRDQLQCHQDVLNSCVAQWNSYQEARQTVIDLMNEVEKKLTEFSTAKAATNQEAEEKLRSHKSLVSMVNSFQEKLTGLEEQASQLEQIGSDASKATISRSMTTVWQRWTRLRSVARGQERVLEDTAHEWRTFREKMMKVRSLTEEVKGRVPDCTAEKASKATLQSHLDQYELVSQDLERELSSLTLLRQYALSLLHDVEVSVPTADHEQLPSLKEIKAVQDQLESLLQKARAGKSRVQQELSDREGVERGLSLVKSWIQDSRELLLNPTSDLDILSQELEVMHGELITHRQNVDK---LAEQQQSKYLDLYTILPSEISMQLAEVSLALGSIEDQVQARERDIQKSRVIKEEFNSRIHDVSEKMKAVSTALKEKATDIDQAKDEARRLCDELDCCGRTLAELEAAVQDFGR--RNPLIARQLADAIAKLREIHHHTLRLADYKTIWLKKADAHLDEYNEMFEFIVKWTDRARSLVKANIIWNSSSHLQEQIRMYQAVLRESRELHGDLDSMQEKVEILSETLQVEAMGQQVSELSRHTEELEQSIRSRLQSLQDAAKDMEKFESEVKVLHVSLDQVQATLTSPELARLSLKEQLAQRQRLLADM--------------------------------------------------------------------------------------------------------------------------------ESFKQQVEAVQECQSALRVPEEVVTSLSICRTALNLQQEASQLQHTAIQQCNILQ---------------------EAVVQYEQYEQEVKNLQVMIEDAHRVIQDQPVNTSNIQELQAQINHHEELAQKIKGYQEQIASLNSKCKMLT------------VKAKHATTLLTVSEAEGLTESLEELDGELIKRKSQ--AQVSMSAGRSQSLLSPVTEESGEEG-ASEICSPAFCPSPS-STNTEAVIS--------------KMSMGRSSLTRAPVQELYNPALES--VASLDDLQRS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WETLKNVISEKQKTLYEALEKQQRYQGSLQSISSKMESIETRLNEPPMHDL----------------------------------------------------------------------------------SPDRQMILHQNQMEEIIRLQDDIHELQSS------FTEELYNPDSVDSDSADQLAMQSSLTVLAER--------------------------------------------------MATIHMKASGKRQILEERQSERVEKQQQAQALQHYLNQADQLDQWLKSTHGYITSCS----QDSDAEEQLTDCQNMLLEMEEKVLALSELSRHS-ESLLLEGRPENREDAEQLARKLRTLKGSLLELQR-----------------------------------------MLQDKQINLQATLIWEELKGPQRASDSLQEASDSSESDSTLSQSPNMQDWLAQARTTRSLQHQDTLQKQKELEEQLAEQ--------------------------------------------------------------------------KKLLKSVASRGEEILTQQASPVRAS----ATETLSPDVELEGDSEAVKKQRRKRWESLKKDMTTKLQLLMNTLEQDSKQPFYSRTAC--------------------------------------------------------------------------VKTAAPVYKRETHVQDKSNLMSLHNGFSQTIQEMTPQA--TEREVILMEQQLY------------------SAVTATSSWVDDVENTLFSGPALLTENADTQLSN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HETLGKEVTEVTQEVGHTQGLIKGSVGLSEDEQSLMKDTLDCLTRRLGALDSALDRRCDSMR--------------------------------------SRMRELSAFQTELQRLFTALSESKFQIIQKMAGVLDHTTTKQIETIAEAEETLKDFEHRITELKARGAELQPDQ------------------------------------------FSTNELLKLQDAYEELVMTVGSRRSGLNQNMALKNQYERVLQDLIDLVDTA-----------------------------------------------------------QDKMTADQKMIAASVEDVHNLLDKHKEFFQGLEWHMVLTETFYKKSSAFVLPRERQTLEETLARAQDVLKQAHKKGVELECVSETWSRLVLDYQTLYRLLEVVEGSLPSVGLVEETEERLNERIQLYQALRSSLTEHQHKLHQVLEEGKHLLSYVSCSSLENQLTVLGEHWLNNTTKVNKELQNLQSMLKHLTRYKSESGELSRWLLEALERLEFWNTQFVAGPQELETVKGQLSAFLEFSKEVEARSNLKASVLNEGNQLLRLKKMDTASLRAELACLDSQWSELLSRIPIVQEKLHQSQMDKLASRHAITELVNWISLMERVIEEDEENLKGAVGSKVIQEYLQRYKGFRVDVNCKQLTVDFVNQSVLQISGADVESKRSDKTDFAEKLGAMNCHWQILQTRITERVQYLEGLLTSWVEYEGKVQGLQAWLDAQEERLKRKHRIENLSSVQNALKDCQEMEVMVKEKERELERVEEQACALVQNKTDEACAVVME-SLRALNNTWANLDHLIGQLKISLKSVQDKWNQYKQASEEINGYLTEGRYSVSRYRLLTGS-LEASRLQVESLQNLQEELEKQESSMRKFGSVTLQLLEECHPSVSDTLNNTLKDINARWSSLQEEIVERLKSSKALLQLWQSYKDLYGQSDSSVQTLEEKANQMLKTASHKDITEEEVSAWIQDCAELLRSQAPVQASLQVLMELGEQLKQQVDTSAVASIQSDHLSLTQRLSVVEQSLSRQQVALQAGVRDYETFNEQLDSLSRWIVEAEEVLKGQDPNGSSDQSLIQDRMEDLKKQMLKFSSMAPDLERLNELG----YRLPLNDSEIKRMQNLNRSWSTTSAQTTERFCKLQALLLQQQTFLEKCETWMEFLVQTEEKLAVEISGNFQSLMEQQRAHELFQAEMFSRQQILHSIISDGQHMLEQGQVDDRDEFKLKLALLSNQWQGVVRRAQQRRGIIDSLLRQWQRYREMVEKLRKWLLEVNHQTQSLQAGTPVPLQQARAMLDAVQLREKVLLRQQGSYILTVEAGRQLLLSADSRAEAVLQEELLNIQERWRNANIRLDEQK---KELAVLLRDWERCEKGIGGSLEKLRAFKRQLSQPLPDRHEELQAEQMRCKDLDSMFDGWKEDLTHLTVLRESLSSYISLDDLRVLQERIELLHRQWEEICHQLSLRRQQVSEKMNEWAIFNNKYKELCEWLTQMESKVSHNGDVSIEEMIEKLRKDYQEEVSAAQENK-----LELQHLGERLARASHETKASDIEHKLSKVNERWQHLLDLIGARVKKLRETLVAVQQLDKNMNSLRSWLAHIETELSRPIVYDTCDYQEIQRKLDLQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRSLDRRWRSICAMSMERRIRIEETWRLWQKFLDDYSHFEEWLMLSEKTAALPNSSGVLYTIAKEELKKFETFQRHVHESLTQLELINKQYQRLARENRTDAACSLREMAHNANQRWDNLQRRVSSVLRRLKHFISQREEFETARDCILVWLTEMDLQLTNIEHFSECDVQAKIKQLRAFQQEITLNTGKIDHIFLQGEALLEKSEPIDAAVIEEELEELQRYCQEVFGRVERYYKKLIRLP-LTDDEHDVSFSDREFDLDEAADVSSFPWSERLGDGFLSPLPSS----SRSAPLRAERSGRDTPASVDSIPLEWDHDYDLSRGLESAS-RALSSSETGDQAEDDGYLQGSASALSDVVIPESPEAFLKLTEQTLRSSAGDAGSLETHIRQLDKALNTSCFHLQQTENIIRSRTP-TGPELDATYMGYMRLLEECRGSIDAVKRVGFELKDEDDKISGFVNPNS--SESQTSGVIERWELLQAQALSKEMRMKQNMQQWQQFNSDLSSICSWLDQTEEELQQERGLDLGTDIQTIELRIKKLKELQKALDKRKAIVLSINLCSAEFVQS--DSEEARELQRRLKEMNNRWEKLSSSLDEWRTALQHALMQCQDFHEMSHGLLLWLENIDRRRNEIVPIDHTQDSDTLQEHHKTLLQIRRELLDTQVKVASLQDMSLQLLVHSEGSDCLEAKEKVHVIGNRLKLLLKGVTRDIRELQKTLDISSSQQDLSSWSSADDLDTSGSLSPVSGRSTPSRQRPPRGKSSVSEPGACVSSLLHSRSLNAAGSAFSHSEDEERPSWCRSFLKRVFWAALPLQIILLLVLIVACLVPTSEDGYSCAQLNNFARSFHPMLSYTNGPPPI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MRD1-1", "uniprot_id": "MS300_DROME", "id": "M9MRD1-1", "name": "Muscle-specific protein 300 kDa", "aln": "MADSGGPGSKHMDPTTIDAGGGGAGAAGGDDVPPVPAVRRRRAHEQKSSREQVLEEEKSQQLETSTVTRTYMKTITTSLTTSSSSNVEEFILGEHAAGAAAAPSPNQQRLRQKVAQYEKVWSDGSSPVKRPAEQSSDELRLTDDQDEYDAENPFEIDVHEIERRLRQERQRGLAEAEAAKLAFQQVQLRHTTPPRRVEVTSDQVASPFNVTLRTTSRMSPGAEHGNVEEHLAPFNVTLRTTRRTKKKEFKELENFLEGERTVREVPSADGVRTIITSSMTSDGGYAEEKIYRHGEGYVSPRDSPSWSRSSYSSERSSVTPPRSVDLTAGGRRILIKLEQESELTEENQTRDETDLSFGRQEVAMATGNIDITVGGSNPRRRLYQQTTVQVGGGNRTSPQDSTPQRPRDLDLAGTTKTMLTSTPIGTKEQPQTGPKTLVSPAATCQLRGSSTEEPRKIVSHKTITSTTTKSTSSSTSATSSSSTSRKLIETSPVVVGKIAQIRTGKSNASDNDIDIDNDSDTEGRPASSIVIVSTPTRPTTPATASVSASAVTPSASISATAAHALSGIGTFSKSLRQDYQTLATQSGRSNESPSDQEYQEFQSTMASINYARSNSQYDSHIKEKREEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLASKR-------IKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHG-----DLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLHKYPEPKGASRDQSHVQQEADELRR------------------FLVEKTTEYEPMVMMSSFPRDFGEYLLARSEVDAHLAAYNRLKQLIESQSGFLQVSRQ----------SWEEINELWQRLQYQMMYWLWLLDSELPGDFGTVGKWLAEAEKLLMDNDIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAK--RSPVAQQIPLEQLRNMERRLQEVGPKAAERRIRLKFLEHKCCLIAFLNLVENKMRGWTGKYGHEEKVAQQLEQYKNFVSRNKIFQEFQKAFVDMQQVVEEYKRDGNVP------RKEINDIDRFMYETEERWKRVSMELKCCQNSLEEVVNCWRSWNQLAPTCEEWLQLAEQKVNQSEDERLDFFQDIPVWKDKFDALASSANYLIASCEEPIAQQLRQRHGALSERFERLFANTKQYMHAGDIIRSRQEYKSGIEQLSRWLRGAESVLDQRQVLGNSEQVKEYGQQLQQLASEIDDNEELFKTISRNFQSLIQDLSRDEVDKMMKLLKQEKESLVRIRAQLPAKLHLFHQLQIQQESLEAGQKEIHQWLSEAEQLLGTHN-LSGGRDAINEQLHKHKTYFSRTVYYRSMLESKNKVFQNLLKAVSSDDKIDTAPASQQMQQLNERFNYVIQNAQQWEQRLDSAAGGWSNFKDNERVVSEWLTQAESMLVEKHIESKTTIETQKYFFEQVNDRWMNDLVQSAQQLLTTLPAQEQPAVVHSVEQLQSRWKNVLSQAPLHLLKLEFRLDENAFYQSLKDVEKELQLEQQALNRNEDVDSILQRNQQFLLQQDVVPRLERCLQNMQRLAQAHRQQQPGDISLDQAYDNAKSQWQLLSNKLGDMRQTLQQIPAQWQGYHLKFNDMVDWMNGVDQSLKNIVNEVNTMEEFEKEKVVFQKICQDADNKREDMKWLVKTLDSLLSYATEDEANLEQKKLEDLIARYKNLIPTIEITMVKTEVFSKCYTYRREVHEVVCLLS----KVKDQTANIPAPDSLDRVNRLIEEQQYAINQLDHQRPHIMSMLQRGRDLIKDVHAPAFVNAEVKNLETGWNQAYTETSDKLQALKGTQAVWSEFVDQKNDIFSMLQTAETELRSLTPLQTDPKNVSQDLKSKRDLNVQLQQASHQLLPKLHALKSELAPLAAPDKRPILEKEVTEVEKMFFNTMEHVKDRVGYLEDYSAKWNNYKTRLAELQEWANKVAPKNIEALQSEDLTPEERVVKVQAFKRILGDRMKQLDLLAADASELAPKEGNIAEAKRLKGEITKLQEVLSAINRNVDHQAQAVQEDLVNWQQFQAGLQQIKPAVEQSEVKVNNVVSKPISLEEAVAMQQNAQQFETQCQEQLDKLHGISNISHKMLCKTNAPDELDAMHSRWTAVHENAKQASAKLEKLVANWKSFDADAAKLEDWVGQGEQQMSRRPAVLNTPHIDKLEKELVKLKSFNNEISQQQAKLVTLGQNADQISLHLAPEGAAALKDRVNQMKGKLQKLSEATRGHINEVSDAIISRQDFNAKLVNFSNWMEQLRNQVTQVEEINPERVETSLHVIHALLQEHADKKPSFNAIYDEVKQLALGATPEESNALNDAYTALVVNYQNLETNMLQKKAALEKWTELLGWKNDTESHLNYLKHQLDKPEGPAAEELSKVIDEIDNLGQGIGYWKGQAKEID---ENPAIQLRDALSRRPLIATQIVNDVENKLENLKLRSQSQQQQIQQMTVRKDKFHALEHNFGQALQENRAKLDEILRQHPTLNNIDQIIADLVALNDALKYQADLKNRIHDEGSLLMREDIASMPAIQESLLIMDKNYDSLQNEIADRIQKYNLISQALREYADSKDKFSKELKKAEDLYNAIPQQPRDETELHQASEKTRKTMEQLRKSKLSLDELERRGNNVGKLFSAIGEPIPQEVPQEVTAAKQHWQDLHDKTAKNAHVYETEAVIWSQIEDAKKDLLPWLSETNQGLCDAADNSIEIEFGPMRLSKYRTELPSYQALKDSIVEKTNDLVKINKGAEIP-ALSALNKLLSEQFAEVNNNADRLSAITTSFNDQEQELRRRSKEAGERVSKLREQLIKCDDMSGDNNKIMERLQQCRALRGELDNSGNEIDNIKQKVDELRNLYPTFSESIIPKELNNVQKRYENVDLYAKKIESSLLQFLKKFHADKVGMLKRIIATQREKVAWCQPESSSDKYNLDVKKSSLQEVSKSIDDCKARHAETLKSLEMLKAVESPQNLAELTSDAELLRKDMQALQDSFDQIKGILDENVDLWSQYEQSNEQISNWLRDVEGRVKAETSSQVNLSEVPQKLQELSILQQDVLAHEPIINNLEQTSQQLIEKNPEARIGQFVTHLVQRYQAVSKALTSYIDKIRGAQLSNANFAKAAKDFNEWFGDAKIEFQELARMGSPGSSSATAQQLQTVKNYIKTFDNGQILLNNAVDIGEALYPVVSPDNRERIRADLRQMREKFDYLRDEANAFMQQVEGVLIQKTSIEESYTQVSHYLNESKAKVPTTDELYPTLATKKAALQNYKTQLQEITLHKNALKQLHDKAVTLCDDESERKTDESIQEYNTLSKKISDRITTVGNHVVKHEAYDQVLEKAQDWLNTIKSEAIDILNETTFEKEGAEEKLLVVENLLQHKPEGDSIFDTCHKLLETVLTQTHPSGHPALLKGFEEPKQSWEDFMTLCQDSLVKLKQLCSKWDEFDTIIEELDNWMKNVEAVVKNQNLKSTAEAKNAHLKQLQDISKDIERRGAAINELMDQGREIEGETDLNLKLSRLNTRYQTLKNLCKESIAKYVNYVKDHESFDKDFDSFKQNLQSSVDELAKTNEIVGDQSVLQDQQNKLREMSDKRILDSTLFEGLIDRGEKLYGHTSPEGREIIRQQLRALRTLWDNYTDDLNSATQKIDQCLLQFNEFSIAQDQLTKWLKDVDKAMQSHTEPKTTLQEKRAQLQNHKLLHQEITTHNVLVDNVCDKAQILVDQIKDNSLNVYLTSIKQLFQSIVQKSDEILHNLDDCVQKHNELNNALSSAKTWISNEKAKLLECDDAYGEKADIKRKIETLGQLAQNKPQAMKIISDIRDLFEKVKATTSEKGNEVLDKEIEELETTMKSHFDDIEGIEGKQKDVLAQWDKFEKALEELTKWCRSAEAVFREQQLQSTLHEKVEQLEKYKIQRELILQKEKEIDAFGDAAHALLNNCGADRLKTLTTQITNRYQLLQVLSKEVVNRWSNLVDDHQFYQDKYNEVDLWLQPIESQMAKVLLDEPTQSSNILQVLLSEKEQAESLFAALNAAGEKALPETSTQGREKIRKDLRDIRDRWDKLDEGIRNLEKRQEAQGVQLSSYQDILNQTVNWLDQVEKLIHNENPASWTSAQEIRSKLYKYKATNQDINSHKRIVEAVNEKAAALLGSAAPANADEISKAVAEVNKRYDQVGQDCAKLVADLDGAFDVYQQFSELQKAQQDYQKNLWDRLTGYSDYSGNKAALQARLQKINEIQDALPEGVAKLKSLEDHIEQQASNIPARSKEVMARDLANLHADFEKFGASLSDVKSGLENRLQQWNDYEINLDRLITWLGEAENSLKNYNLKSSFEEKEEQLNGFQSLAQNLRQNEADFDKVKDDTSELVQSSGETRIAVNVQQVSSRFQSIQATAKEILKKCEQAVQDHGHFNDKYKQCADWLANAQARYDDCCDLSTVASRDDLLKKQVVIQELLAQQPTATQLLNSTVELGEKCYGSTATEGREAIRSQLDDLTFDQLFDNIAITARKIQDKIAKWSGFDEIADSLKSWLDETENALPADIELKTTLDEKRNKLQTYRDILNDINNHQVELGNLQEIAANLPEKTELVDQIIKDISDRFGKLQKRAQNYVERYEGIVSAHQQYSKAVMDAQEFIDATLNTVHYWGDLDLEQISLHTNLDRLKNLKASLADEFPRVDQVRALGEKVIPGTVDVGQVNIKSQIDTTQQEWESLLTTISSTIEAIEARLQHWSEYEQLRDQCLAWIRDTDNNLHAIDLKEDLPKKRAQLDALKALQGDVRAKELEVDNVTEKAQTLLKGPSSNRASGPELVTKYQQIFHKVKELNNRWQQYVTSHEDFDNAISDCSSWINEIK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PTEELVVPITPGPDNLSGEPHNIWFSATTSVDKTPIELSQALIMSESLQHYPGQQKLTQEPILISTKEAIGDRIKQLKQASPQQATPLSNVLHLATLSEQIKELPTEQRILEVNEGLKDLDVAIKNGDKTVIQTTVITVIEKVSTWLETIEYRVYLIRQNSNEGPSEEKLDNYNQLNDELSTIKQNVVQLERQLSKAEPEPQLLQCVDSLKEHVDAVEQVTQQNQVQDSNDLDKWHNFEVLLYNVSSVLADLQQSYDLLINQEYPLSAKLAQLDELEQQHEAAQQQLAHLCQNARAFQRDFPGKKMPQDVHNAFETSKNIANNIQAERERVLQLQSLAEEYEQTLKEFTKITVLADKLVESPIVSSSLEQLNNEVQKQRKFFVNLSHCRAMLESLEENIDSETREKHSELHKELYNRATSLLDKASERSSKLVQAASRWTVLEKGMRDELQWLQVAQQRVPDLSAVTSAD--YDQYTTLYQSLSNDISHHYVKMTQLSGIANKLQLLVQAPNLVEETNEALIVLLKLREEVALYLHRLLVFKEIWVQYEQQTDKLEAFVREAEQELRNIQIPSQPTHQPIEHMRQFWEIKARFELHNNVRTDTG---LSFEKSLQVIPLADEMLQRQFHAQLEDRWQAVAQAIELIQHNIVECLSSEDVPADEKLKMVERELQEIYLTMTSMKGVIKNE--EELCLYIERVQVLRTRVGFIGNELGRIGLQEPAIEPEKVGELFSLSHKISTQIAEELEGASVLR----DQLQAIQEGISNQRKHQAKISVILDECEAAER--------QGADVLEKAVADCQAAGEELVISWQEIMRIRQMLHTLPMRLKMSVSPVKLERDISQLQDDHAFLESKCTNIMAILRSRLAVWLRYERQLELVHGSVQETDFMMELIRVHGQVDYERLRKATERLEGLAGDLHNREQLIDELKGAAKPLIESCDVQIVEQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELWDKYRNASAAVKNSIDQQMDAVKSLEQPLD-----------ALQHAKVCQDNLTTQNDRILELRDIVAKIAADVGLDASALMQGELDALGQRLAECKDAITTLANVAETQDKERKELDKEVTLAKAYFNNVQQDISREAPQNPKES---EEQLAALRAHLQTLARTEEQLRQLKERHQNSEVAPSVASSDDDGILEVLALWQKIFQDTFQEYHRLSTRLARSQNSSEALRLWRQYLQHVQSFLSCAIPEDYSSLREQQQLCAIHQNLLISQQSVLSETPLES-------------ELSEQYKALTNLHNETLSRIMQRNGELERRVSGWNAYRQQLAALLDWLRQR-EAERNALQLRYIHLKRVPHLKHRLDAMIQQLDQGEQQSKALQEQQQELARHCDDALATAMRMEQASIGQRISNLRAALKTWQGFLQRVTQLSESYEQRVNQLQQEFGAAQKLLDANSESLPTQPAAIEQLLGSLRAQRVQLGAQVSALESLTVTQEELKECISPHDMKTIRQRNWLLWQQHADLDYQLANLINSIEERLSLLSNYQIRYDRISQWLQRLEQRVEKDADVTAMTNPEQAAKQLEQQVNSELQLRDKEREWLLSTSRELLTLYSEPEVRSQVQQQSDSLIDRWQRLKYLAKQKATKIGELKMTLLRLEERIALIRAWLFEVESQLDKPLNFESYTPNVIEAKLKEHEQIQRSIEHHSSNVGEVLNLVEMLLNDADSWRTQVNTSGLAASAQNLEQRWKNVCSQSAERKARILTIWNLLQQLIKLTAEHKNWLGKQE-----SQIAGFERDQKSHSKHKLEERQMELRAKLEELESQSVNLRQLEQIYAKLAMSAGVEPEN------------IQKLTLPTKVMVSMWRQLTPRCHALLDAIDKDAKLMREFNNAQLEATNSLNAIQKALEQLPSAEN-------QQTSKAEPKAVLQRLESLEKKLQDAQQHVQQADNLAQEAKTRTKQQP-------------QLKQLLELVSAYTTLWQTVQTR------------------IVTLKTTWLTRAAQAAASLPVSEAANAAVQVNTLSQRKLRQAQQMQRETS-------------------------------------ITAKDAYIMELQTAITECQNNLDELQRTVVDKTRKPGPQKIAKLLGNAQSSTELVKHLSHLLLTECKADDQAAEVDTVAELTLRFDTLQSQWKARQQHDQNASEVGRLTCPLCTQRNWQQIDNDLWRLEQWLQFAESTQKAQS--APPSNIELLEDVTQDHREFLLDLESHKSIISSLNVVGDHLATHTLDTEKARQLRSRLEADNERWNNVCINATKWQGLLQTALMGNSEFHQTIGELVEWLQRTEQNIKASEPVDLTEERSVLETKFKKFKDLRAELERCEPRVVSLQDAADQLLRSVEGSEQQSQHTYERTLSR-----LTDLRLRLQSLRRLSGIYIVKLGAVLGYEGDNLG-----VPLHMLSSELLDNTTLSTSSMQAAAPNTENANNTDGGDAVDGDVINTTVLARG---ARFLGRVARASLPIQALMLLLLGVATLVPHG-EDYTCMFSNTFARSLEPMLSYPHGPPPT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*. : . ::. ::*** ***:***:****:* *: **: ::**::*::** **:********::** *:*: :* * ::* .***:** .:: *******.:*:.****.:****:*********** : ** * :..*.**:**: . : . * : .*:::**.** : * *:****** *** *:** ::*.**:.:**:: :: ***:.** ** :**.:***.:***.***** *************** :**: : : * .. :: * : :..: **. . ...: : ::: :: * : :: * . ::: *::: ::: * **..**. :*.:* ** .** * :: : :**** * ****:** .: : *.: ** . :* :**.:* .*:: * ..: : ::::* * * *:::* *.*.*::.* ***:.:.* *:.* *:. *:*:::: :: ::*..: * : :* :.: :*: :: :*:.:*:*::. :. ****: * :.. ..: : **: **: :.*** : :**:::* * ::. : .:.*:** :*:* ::::*:*: *. *:..** :.*:* :*.:: : :::* . * : *. :. :. : :: *:::: .: : :* ::. : : :: ..:* .*: :.. *:.* ::: . * : : *.:* . ::: * : ..: : : . :.:: :: : . :.::. : . : : . . * : .::: ::: : ::::: :*:::::: : ..*::.. :.: * *.. : *: : :. :. ** *:::* :* ::::.::* ** *** : .:*.:*:.:**:: : * ***:*:. :::. : :::: . ** * : . : :::.:: *: ::. *: *: ::.*. : :: .: : :.. * : * :* : :*.:: *:. . *: : .. :. : * :.: :. : :.** . * * . .:*.:*: . * .* :* *: :. ...* ::. *: : * : :.: * ...: ..:::: :* : : :: .: . : :. : ::::**: . . : : :: : *..* :: : : . : . :.: :.:*.:*:..::: : : * :* .* :: :*: :. :.: . . . :: : :* .::*: : :.: :. * : .::.:*::. . : :: ::. : : . : * :..:. .*: *:*..:*:: . . :.. . : : :*: .*:::: *.: :: :. * *: *. :. :. : :* ::: : .. *::..: ..**: . *.*::.*: : : : : : * : . : *:: ** :: ::.*: . * : : : . :* :*:. : . :: :.. : . :*: * .* * : : ..: .. . : : : .: : . * . : : *:. . : : : : :* : :* : * *:: :: . . .. . : ::. . : * :* :. :* . . . .:.: ::: :: ::*.: : : . . *: ..:: ::::: . : *. : *. ::: : : *:* *: : . ::*:.. : :.* . : ..: :: .::. :. * :. : : : :::* *. . . *:.*. : :*: : : : * . .: : ** : :*::: . :. * . . * :: :: ::* *: :: .* . . . * :: . . :: * .. : : .: : *.: . :: : : .* .:: :: . : * *. :: * .:: :: : .* * ::. .: . .:...* * : : : :: **:.. .* . :: :: * . : : . :..: *::* .. . : . : . *::. * ::*: *: . * :* : .*. . :*: ::. :. ..:*: * . *: * :. :: .: . .:.:: .:. * ::. .:: ::. ::.. . : : . . : ** : . . :: : : : * :* ::* :*.* . :* : ::::: ::: :* :. :.*: :. *.:..*: : :::: : ... :: :.:*:: . : :. *: **. *: * : . . :: : *:..: : ** :*:: *:: :. *:** *:. : : : *. : .: *: * .: *::: :: .:: : .: *. :. .::*.:* * : .:. ** . : :.* :** **: :: * :* *:. : *: * :*. :: .: .: . *:: : * : :.:: .. * **. : ::: ::**: . : :.. :: : : *: * : : . : : : * : .. : **. .:: . ::. : :.. *:* .. .... ::::.: * * . ..*: : * . * *:. .: ..::* : :*.. *: :: : .**:: : : : : :: .: : ::.:: : :::*::. *: * : :: . * : :**.. . *:: . .* :*. *.:: ::.::..: : :: ::. .* .* ..: . ::: :**: * . *::*: .::: :*. :. .:*. ::*:::: ::: :..*..*: * ::: *: :: : :: :..** : :.* :* :. ::: :: * *:. .* *** * :*:.*... *: *: * .* . .* : : :: : * ::: : ::::*. .::: : * : : : ::.:::. : .:*: * :: : :*. : * ** : :*:*. : ** .: :.*: ** . .** *:. * * . . * : :: : :::::. *: * .:: :: * :::: . :**. * . . :.. *: * :: : : :. :: :. ** :*: .:*:. ***::*:*** : :: :: . . :: .* ..* .:::::.. : *::.:: * .:* *:. *: * ::.: * :::: . .::. * :.. : : ::: . * .*: : : : . * :* :*:* * *:: :*: : .*: : .: : :.: ** ::* . . : :*:: :.* . :: :* .: ::: *: .**:*******:* :* : : : .. * :*: :*:*:: ** :: .*..*: **: : . * :.:: :. :***.:: .*: :: . * .* *. . :***:. :.: : :: . :.* : :: .:.:: :: : * . *: : *: .: :: : * :: : :. : * . *: :.* :: * . :.:: :.:. : : : . ::* : :..: : .:* .. * *.. .* : . ::: . : *:: : :: :: . .. * * * .. . : :: *:.:: : . :::** :: :. * : :.** :::*: .* . :.** * . : : :. : : :*.::* : . . .* *. . :: .: **** * . .: .* * . ::. : : : . *. : . . :* . :..: : :* :: : . : * . ::.*::: :. : . : ::. :*.: *. ::** . :: : *:*: : :: ::.*:* :.*:. * ** *: .:.: .**:: : .* *:. . * ** :*:.:*.:: : .*: :. *: :**:*.:.*: *.:.: : ::. * .:: : * :: * : : * ::: :: : * . *: .* :* *: . :.::: .. :: : : . : : *::: * : .:. : :: : . .:: .. . *:::: *. : .:* . * : :.: .. :. : :: : : :*: : . : . : : :: . .: :*:.. * **: : . :* :.::.*::* * .::: * *. . :. ..:: :.: : * * .* ..: . * :: * : .* . :*:.:* ** *:* * : * .: :: .* : :::. : :: :.:* .: . : : : : . *: :*..**:: : * :: ::* . . :: . :. *:* :..:. ::::*..* : .. .: :.:. : : : * . :. *:: ...* : .: . .::.:. . . *: * : : : : : :. : *:* . . : : :: .: :. : . :.::*.: * * :. :: :: :: * . : : : : :: :: :. : :* . ***::: ::: : * :. :: : ::.:..:. * :..: . : . :: :: : * : : .*: : :.: * : . :: : * :* :. : : : .: .: :: : : .* .. : : . .* .: .. ::: : : :.. : .*. * :::: : .. . : ::: : .:. : * **:*.:: .: * ::: :: ::.: * *.: : .*::** :: *::: .*:. :..:: ** *.: * . * * : :.:* : :::: ::: : : :*:*: *::: :. :: . : : * *::*:. ::* :.:*. *:.: .* .: : * :: :: : :. :: :: .: . . ..:*:.* ** ... ..* * ..* .: : . : .: :*.:*. .* : :** ** :: : :*: : ::.:* :*. . :* : * :. *. : : :::: : : *: : .*** : ::. .:.::. .. .* ::. . :.. :: ** :.: :.* . :: : :.: . . : : : :::::* . :: : . .. * :::* :.* : :*. : :: * . : .:: :. .. . * ::. *: * . . ::: . ::: * *:: : ..::. . ..** . : : * : : : * .: : : * : : . * : :. :. . :: : : : ..:: . . : : * ..::*** :.: : . .. :. :::: : : : * *::: : .:.* . . :. :: .* .: *: *... ::. : .: . . :: : * * :: : . . . :::: : :: * :. : :*: : : : . * .**: *: *: . : * * *:.*:: . *:* .* :.. . :. :: .* *:::: : *::::* .*. : * : .: . :. : : :* :*.:* ::. :* . *: * . : : *:* : :*.:. * . : : *** * ..:..: *: * .::* :....* .: . * :: *:.* : : .:*:.:: * :: * :.* . * :* :: . .*. . :.:: . :.* : * * : ::.:* : * :*.:: : .: . . :::. : . ..: : : *::: : :: :. . :. . *. .* . * . .:: ::. .:*: :::* :: : . ::: .:. : *. . :::*: *** : . :*: ::.: :* . ... :. : * : *: :: * * :: : : . : * : :. *: : : .: *:.* :*.::* : :: . : *::.*. : : : .:::: *.. *:: : : ::**: *:: .::: : .. : :. :*.. . . : : * :: :: :*. .* : :* : .: *:* :::: :: : : : :.: . :: :.: :. : * ..: :::: *: :: .:: :* :*:* .: ..: . : :: *. :* :.: :*.: * : *. * . * ::* :.: *: *. ::. * ***: :.* ::*:*.:* . :. *:. : *:* : .: * **.* :: : *: **: * .** : . : *::. : . :: : : : : . * ::* .*. :.:: * .* :: *. : :.:: * ..:*: . : .: : : *:.** : :. : .. . * * : :: * :* .*: :.:* ** :* :: :*:: :.: *::. : :. : ..:.:** ::*.:*.::.*: *: *: :::: : : *. * *: *. *::: : . : :***:* * :..*: * ::: :*::.: :* ** .:*::* :*: ::: : *: **. ::::**.**:**:.*..**** *:**:*.*: *:.: ..: :::.*::**:.:*: * **: :* *.* *:::. :..::** .* .. :*. ... :*:* * .:: * :** . : ::* : . : .: : : : .: * ::. .:: . ..:* : : : :::: . .:: :*::* : : * . *: :*::*:: ::: *:. . .:. .: : * : :* : * : : :: * *: : .* .. : : ::: * * . : . . : :: : :* .*: . :::: . : .:* .**: :. * : * :. : : :: .. ..: *. : . :*. :.: . ::***::.** : ** :*. . ::*. :: :. :*: :: :*:*: *:*: . .:. *::::::*: **. * **:.:. .*: ** *** . **: *: *:. ::. : *:* . : . *: :.. : ::: ** : :*.***: : *** **:: . : :.:.. *. : ::.*.: .: : . ..*::. * *: :... ...*:. ... ... .. .. .. ** *: *:**:* ::**:: :: ** . ..*:* *.****:.*** *.:**** ", "identical_positions": 1186, "similar_positions": 3360, "identity": "9.42%" }, { "cls_id": "homologset.agr.RGD:620547", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62803-1", "uniprot_id": "HYALP_RAT", "id": "Q62803-1", "name": "Hyaluronidase PH-20", "aln": "MGELQFKWLFWRSFAESGGTFQTVLIFLFIPYSLTVDYRATPVLSDTTFVWVWNVPTEACVENVTEPIDLSFFSLIGSPRKTAIGQPVTLFYVDRLGNYPHIDAQQ-TEHHGGIPQKGDLTTHLVKAKEDVERYIPTDKLGLAIIDWEEWRPTWMRNWTPKDIYRNKSIELVQAADPAINITEATVRAKAQFEGAAKEFMEGTLKLGKHIRPKHLWGFYLFPDCYNNKFQVDNYDGQCPDVEKKRNDDLDWLWKESTGLYPSVYLKKDLKSSRKATLYVRYRVLESIRVSKVSDESNPVPIFVYIRLVFTDHVSEYLLEDDLVNTIGEIVAQGTSGIIIWDAMSLAQRSAGCPILRQYMKTTLNPYIVNVTLAAKMCSQTLCKEKGMCSRKTESSDAYLHLDPSSFSINVTEAGKYEVLGKPEVKDLEYFSEHFKCSCFSKMTCEETSDMRSIQDVNVCMGDNVCIKATLGPNSAFHLLPGKGLLLMTTLAHILHHLPHDIFVFPWKMLVSTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48794-1", "uniprot_id": "HYALP_MOUSE", "id": "P48794-1", "name": "Hyaluronidase PH-20", "aln": "MGELRFKHLFWGSFVESGGTFQTVLIFLLIPCSLTVDYRAAPILSNTTFLWIWNVPTERCVGNVNDPIDLSFFSLIGSPRKTATGQPVTLFYVDRLGLYPHIDANQ-AEHYGGIPQRGDYQAHLRKAKTDIEHYIPDDKLGLAIIDWEEWRPTWLRNWKPKDNYRNKSIELVQSTNPGLSITEATQKAIQQFEEAGRKFMEGTLHLGKFLRPNQLWGYYLFPDCYNNKFQDPKYDGQCPAVEKKRNDNLKWLWKASTGLYPSVYLKKDLKSNRQATLYVRYRVVEAIRVSKVGNASDPVPIFVYIRLVFTDRTSEYLLEDDLVNTIGEIVALGTSGIIIWDAMSLAQRAAGCPILHKYMQTTLNPYIVNVTLAAKMCSQTLCNEKGMCSRRKESSDVYLHLNPSHFDIMLTETGKYEVLGNPRVGDLEYFSEHFKCSCFSRMTCKETSDVKNVQDVNVCVGDNVCIKAKVEPNPAFYLLPGKSLLFMTTLGHVLYHLPQDIFVFPRKTLVSTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38567-1", "uniprot_id": "HYALP_HUMAN", "id": "P38567-1", "name": "Hyaluronidase PH-20", "aln": "MGVLKFKHIFFRSFVKSSGVSQIVFTFLLIPCCLTLNFRAPPVIPNVPFLWAWNAPSEFCLGKFDEPLDMSLFSFIGSPRINATGQGVTIFYVDRLGYYPYIDSITGVTVNGGIPQKISLQDHLDKAKKDITFYMPVDNLGMAVIDWEEWRPTWARNWKPKDVYKNRSIELVQQQNVQLSLTEATEKAKQEFEKAGKDFLVETIKLGKLLRPNHLWGYYLFPDCYNHHYKKPGYNGSCFNVEIKRNDDLSWLWNESTALYPSIYLNTQQ-SPVAATLYVRNRVREAIRVSKIPDAKSPLPVFAYTRIVFTDQVLKFLSQDELVYTFGETVALGASGIVIWGTLSIMRSMKSCLLLDNYMETILNPYIINVTLAAKMCSQVLCQEQGVCIRKNWNSSDYLHLNPDNFAIQLEKGGKFTVRGKPTLEDLEQFSEKFYCSCYSTLSCKEKADVKDTDAVDVCIADGVCIDAFLKPP---METEEPQIFYNASPSTLSATMFIVSILFLIISSVASL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UYM9-1", "uniprot_id": "A0A8N7UYM9_DANRE", "id": "A0A8N7UYM9-1", "name": "Hyaluronidase", "aln": "MANQRQQQLLFS---------TIVLIFVGHVNTSVYTPSTVAPLFHRPFVLLWNAPISKCH-QLKVPLDLSLFQAVTTPARVHN-QSLSLFYKTRLGLFPYVDLHSMKEYNGGIPQRGNLSASLEKAKEEFLQFIPDSSSGLAVMDWEEWLPIFDRNFDLKKIYMELSINYTLEQNSSLSPQQAATEAKQQFQKEARRFMEETLKKGINLRPRYLWGYYLFPDCYNYGFDESNYTGTCSEYTKQLNNELLWLWEVSTALYPSAYLPVSKSGSKSAALFVRHQVEEAMRVASLPKHVHTAPVYVYLRPLLTNQKKLYMNEIDLVSSIGESAALGASGAVLWGSSADYNDKTSCEALSAYLSDKLNPYILNVTTAAHLCSKNLCQGEGRCVRKNNNSDDFLHISSESHHIGRN-AGKYVVTGTPSASDLADWKSKFTCQCYEDRNCTATMPSF--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : : ::: *: *: . : . : . .*: **.* . * :. *:*:*:*. : :* * :::** *** :*::* *****: . * *** :. ::* .. *:*::***** * : **: *. * : **: . : :. :*: .* :*: .: *: *:: * :**. ***:******** :. * * * : *::* ***: **.**** ** . . *:*:** :* *::**:.: . . *::.* * ::*:: :: : :** ::** .* *:** ::*.: : . .* * *:. *****:*** **::**: **: :* * *:. .*. :**:... . * **: * *.* ** :..:* *.*:. .* . ", "identical_positions": 136, "similar_positions": 134, "identity": "26.51%" }, { "cls_id": "homologset.agr.RGD:620548", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14061-1", "uniprot_id": "COX17_HUMAN", "id": "Q14061-1", "name": "Cytochrome c oxidase copper chaperone", "aln": "MPGLVDSNPAPPESQEKKPLKPCCACPETKKARDACIIEKGEEHCGHLIEAHKECMRALGFKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0L402-1", "uniprot_id": "A0ABK0L402_RAT", "id": "A0ABK0L402-1", "name": "Cytochrome c oxidase copper chaperone", "aln": "MPGLAAASPAPPEAQEKKPLKPCCACPETKKARDACIIEKGEEHCGHLIEAHKECMRALGFKI", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****. :.*****:*************************************************", "identical_positions": 58, "similar_positions": 4, "identity": "92.06%" }, { "cls_id": "homologset.agr.RGD:620549", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LEW3-1", "uniprot_id": "A0ABK0LEW3_RAT", "id": "A0ABK0LEW3-1", "name": "receptor protein-tyrosine kinase", "aln": "----------------------------------MLP---------AAAPRSPALAAAPAGPSVSLYLSEDEVRRLLGLDAELYYVRNDLISHYALSFNLLVPSETNFLHFTWHAKSKASKFTFDVFQKETALFIISHSHSHVFQVEYKLGFQVDNFVAMGMPQVNISAQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVN-SSKNFTVLNFKRRKMCYKKLEEVKTSALDKN---------------------------------------------------------TSRTIYDPVHAAPTTSTRVFYISVGVCCAVIFLVAIILAVLHLHSMKRIELDDSISASSSSQGLSQPSTQTTQYLRADTPNNATPVTS---YPTLRIEKNDLRSVTLLEAKAKVKDIAISRERVTLKDVLQEGTFGRIFHGILVDEKDPNKEKQTFVKTVKDQASEVQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVISPYMN-WGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01887-1", "uniprot_id": "RYK_MOUSE", "id": "Q01887-1", "name": "Inactive tyrosine-protein kinase RYK", "aln": "-------MRAGRGGVPGSGGLRAPPPPLLLLLLAMLP---------AAAPRSPALAAAPAGPSVSLYLSEDEVRRLLGLDAELYYVRNDLISHYALSFNLLVPSETNFLHFTWHAKSK---------------------------VEYKLGFQVDNFVAMGMPQVNISAQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVN-SSKNFTVLNFKRRKMCYKKLEEVKTSALDKN---------------------------------------------------------TSRTIYDPVHAAPTTSTRVFYISVGVCCAVIFLVAIILAVLHLHSMKRIELDDSISASSSSQGLSQPSTQTTQYLRADTPNNATPITSSSGYPTLRIEKNDLRSVTLLEAKAKVKDIAISRERITLKDVLQEGTFGRIFHGILVDEKDPNKEKQTFVKTVKDQASEVQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVVLPYMN-WGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHRDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P34925-1", "uniprot_id": "RYK_HUMAN", "id": "P34925-1", "name": "Inactive tyrosine-protein kinase RYK", "aln": "MRGAARLGRPGRSCLPGARGLRAPPPPPLLLLLALLPLLPAPGAAAAPAPRPPELQSASAGPSVSLYLSEDEVRRLIGLDAELYYVRNDLISHYALSFSLLVPSETNFLHFTWHAKSK---------------------------VEYKLGFQVDNVLAMDMPQVNISVQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVN-SSKNFTVLNFKRRKMCYKKLEEVKTSALDKN---------------------------------------------------------TSRTIYDPVHAAPTTSTRVFYISVGVCCAVIFLVAIILAVLHLHSMKRIELDDSISASSSSQGLSQPSTQTTQYLRADTPNNATPITS---YPTLRIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPYMN-WGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27324-1", "uniprot_id": "RYK1_DROME", "id": "Q27324-1", "name": "Inactive tyrosine-protein kinase Drl", "aln": "-------------------------MAPNLLTIGLLLT--------------LIASG---QAHLNIFLNLHEVLRLIGVSAELYYVREGAINDYALNFAVPVPANISDVTFTWQSLVDHP-------------------------LPYSINIATSDTEVLPRPILNISRIGDVPVEPQTWGIALKCSGTRNAEVTVTINVEVILDRATNNNTNLIFKRKKICLREEQDSAHEEYDDDDLDLLQTARKGHGGDIHYVDRNDEHVVANGHQAPEKQRPVVTESPVGRGNSGGSKRDFDPMLRENLVPPASGLVTLIVGGILALVLVSTLILIAYCAKGPS--KRHPSNGVHLIKTSSFQRL---PTISSTAHNSIYVCPSTITPTY-ATLTR--PFREYEHEPEEFNRRLQELTVQKCRVRLSCLVQEGNFGRIYRGTYND------CQEVLVKTVAQHASQLQVNLLLQESMMLYEASHPNVLSVLGISIEDYATPFVLYAATGSVRNLKSFLQ-----DPSYARSVTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFPGDYNSLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICLSEFHTQITRYV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V422-1", "uniprot_id": "RYK2_DROME", "id": "Q9V422-1", "name": "Inactive tyrosine-protein kinase Dnt", "aln": "------MESVNKCGKSASTRNCTVKMSRKMWVLSLLALA-----------ALQLHSGSEVAAHLNVFLNPVEVMRLLGVSAEVYYVREGHINNYALNFIVPVPANVKDISFTWQSLAGRG-------------------------LPYSINVVSSDQEVLPRPAINVSHSGEIPTTIQTWSIALKCSGLKAAEVDVTVSLEVVLNRSLNNVTHLVFRRKKICLMN--DSAEDLSED-------------------VD--------------------------------------DPQLLETVMLPPTGLITLVVGVSVAMGSVCLLLMIAYCVKGAANKRQHHQHGGQPMRTSSFQRLNTHPPCQSSMGSAAYMTPSIIAPIHGSSLPRKVPVSVEQQHPEELHRRISELTVERCRVRLSSLLQEGTFGRVYRGTYND------TQDVLVKTVAQHASQMQVLLLLQEGMLLYGASHPGILSVLGVSIEDHTTPFVLYPALNNTRNLKQFLL-----DPACARTVTTIQIVMMASQLSMALDHLHSHGVVHKDIATRNCVIDDQLRVKLSDSSLSRDLFPSDYNCLGDSENRPVKWMSLEALQHKQFSEASDSWAFGVLMWELCTSAKQPYAEVDPFEMEHYLKDGYRLAQPFNCPDELFTIMAYCWALLPAERPTFAQLQSCLSEFYSQITRYV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . . :.::*. ** **:*:.**:****:. *..***.* : **:: . : ***:: : *.:.. .: .: * :*:* *::* ..: : *.*:* :** : :.::: :: : :* * * *:*:*:* : : . :. . : : : ..: :. . * *: * .. :: .. :** . . .: ::. . * . * : ::.::::.: *: *. ::***.***:::* * ::.:**** ::**::** ::* *. * * .:*.: :.**: .*:*: . . *** ** :. .:::: : * *. *:: .:.:* : *:*:*:*:******* *:**::*.:******* **:.***.* **::*::**:* :..:...** *:*** :**: * .: **.::**:** *******:***:*******::** *** * ***.* ** **:**:: : **", "identical_positions": 168, "similar_positions": 188, "identity": "24.14%" }, { "cls_id": "homologset.agr.RGD:62055", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53669-1", "uniprot_id": "LIMK1_RAT", "id": "P53669-1", "name": "LIM domain kinase 1", "aln": "--MRLTLLCCTWREER-MGE-----EGSELPVCASCSQSIYDG---QYLQALNADWHADCFRCCECSTSLSHQYYEKDGQLFCKKDYWARYGESCHGCSEHITKGLVMVGGELKYHPECFICLACGNFIGDGDTYTLVEHSKLYCGQCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASAH-GKRGLSVSIDPPHGPPGCGTEHS-HTVRVQGVDPGCMSP----DVKNS-IHIGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDSLGHGPVSDPS----------PLAS----------PVHTPSGQAGSSARQKPVLRSCSIDTSPGAGSLVSPASQRK--------------------------DLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDE---------------------KGQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMHLAGHLPLGPQLEQLERGFWETYRRGESSLPAHP----------------------------------EVPD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53668-1", "uniprot_id": "LIMK1_MOUSE", "id": "P53668-1", "name": "LIM domain kinase 1", "aln": "--MRLTLLCCTWREER-MGE-----EGSELPVCASCGQRIYDG---QYLQALNADWHADCFRCCECSVSLSHQYYEKDGQLFCKKDYWARYGESCHGCSEHITKGLVMVAGELKYHPECFICLACGNFIGDGDTYTLVEHSKLYCGQCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASAH-GKRGLSVSIDPPHGPPGCGTEHS-HTVRVQGVDPGCMSP----DVKNS-IHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDSLGHGPVSDPS----------PLSS----------PVHTPSGQAASSARQKPVLRSCSIDTSPGTSSLASPASQRK--------------------------DLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDE---------------------KNQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMHLSGHLPLGPQLEQLERGFWETYRRGESSLPAHP----------------------------------EVPD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53667-1", "uniprot_id": "LIMK1_HUMAN", "id": "P53667-1", "name": "LIM domain kinase 1", "aln": "--MRLTLLCCTWREER-MGE-----EGSELPVCASCGQRIYDG---QYLQALNADWHADCFRCCDCSASLSHQYYEKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSH-GKRGLSVSIDPPHGPPGCGTEHS-HTVRVQGVDPGCMSP----DVKNS-IHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDTLGHGLGPETS----------PLSS----------PAYTPSGEAGSSARQKPVLRSCSIDRSPGAGSLGSPASQRK--------------------------DLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDE---------------------KTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHP----------------------------------EVPD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IR79-1", "uniprot_id": "LIMK1_DROME", "id": "Q8IR79-1", "name": "LIM domain kinase 1", "aln": "MHHQQRLRANGGRGGTGLGAGSGPVSGGHSPLCAHCRGQLLPHPEEPIVMALGQQWHCDCFRCSVCEGHLHNWYFEREGLLYCREDYYGRFGDACQQCMAVIT-GPVMVAGEHKFHPECFCCTACGSFIGEGESYALVERSKLYCGQCYGKRSCQPADAKARITTAG-KPMHSIRLVEIPKDATPGLRVDGVALDDGCPTVRITDLFCNFFLWLTSMAEQCCGAPYRIDVNLTNLHIGDRILEVNGTPVSDSSVEQIDKLIRSNEKMLQLTVEHDPVQVCRSCSQADIQRAMSASTLILPLSTSASSVEVGRERLYKTPGEQGTKARKLRQATNASTTIPPAAGATAMTQLKEKERCSSLSKLLDEQHQAQQHSAHPQLYDLSRTQSCRVVQKPQRIFRATDLVIGEKLGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEIIGRVEADPDFMPRNSDFSLNQQEFREKFCAQ-CPEPFVKVAFVCCDLNPDMRPCFETLHVWLQRLADDLAADRVPPERLLHEIETFQEWYASSEDALSPTSQRSLNNLDELVKSAVDSEISPVEKEKENMVIKPQDIPKSPHLGKDFSPSGERLRDSMRARRRQRFLGAQEERRNLTPDTESKERALKKALKKCRPFGERGYLVDLRAGAELQLEDVRDLNTYSDVDSSCDTSLNYHDVNNLPAAQEDENTVKPGKEELLEESTNKPSNQESQHHRLAIDDMRTRLNQCRSKFEHLEEASRRNFNQSQHSMKNFFKTPPVALKMFQRLEHEAAALNGGNNCPPPPPRTQRINQTPIFGRKNPPVAIVGQKLQHAESLEDLASSGVAKQLATPAPKRSKATATTKGGQSSNPPLFLPPSLNISVALNSNGNVTTTTNTNSSCPPSASDWLPKKHKLTLPLPSAQQQRTSSNHRLPMCNNKGKTLKPLPSRTGSQGIPASNCVSPTRSSRPGSPTKHLAQRHTAATAQRLTNAAATHQQQHQQQSSKTTRLNILSPEKVHRLGARLTDQKQKMREEAAATASSVGGAGCAAGTAAGSLNGHRTIGSSGTPNSAVGERRRRAAPSPPVRTHFNTRC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . * :* .*.. *:** * : : **. :**.*****. *. * : *:*::* *:*::**:.*:*::*: * ** * ***.** *:***** * :**.***:*::*:***:******:** : *. : :.* : *:: **.** .: * * .*::* . .. . : : .: * .. **: : :*:******:****: : .:::** **:...::****:**** : .: . **:: :...*: .:.**: ..* .*.:.: . :.* **.*::* *** :*:****.:**: ** **:* **:.:*****::*****:*** * ***:**.*:*** *:* *:* :************:*:::***: ** *: :*:. . **.*** :*:***.**:************** ******::.*:******** : . ** *. :*::***************::* .************:********:****::**. **.** : * :::*. ** .*. ::. ****:*: **.* .*. **: * .*:.. :* : . * * * .*..*.. . ::*. ", "identical_positions": 291, "similar_positions": 191, "identity": "23.1%" }, { "cls_id": "homologset.agr.RGD:620550", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70475-1", "uniprot_id": "MYT1L_RAT", "id": "P70475-1", "name": "Myelin transcription factor 1-like protein", "aln": "--------------MDVDAEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQ------PQEPAPKRKPFAVKADSSSVDECYE-----------------SDGTEDMDDKEEDDDE------------------EFSEDNDEQGDDDDEDE-VDREDEEEIEEEDDEDDEDDDDGDDVEEEEDDDDEEEEEEEEEEENEDHQMSCT--RIMQDPEKDDN-------------NNDEYDNYDELVAKS----LLNLGKIAEDAAYRARTESEMNSN------------TSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDR-------------------------SYAEGMSQ-----------------------QDSRNMNYVMLGKPMNNG-------------LMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYS--DMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMT----------KGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYY--DPSRTEKRESK-----------------------CPTPGCDGTGHVTGLYPHHR----SLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSN-------RNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPR----------------------SNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNAS---PSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYT------------HDMEAAHMAATAILNLSTRCREMPQNLSTKPQD----LCTARNPDMEVDENGTLDLSMN--KQRPRDSCCPVLTPLEPMSPQQQAVMS-----SRCFQLSEG-----DCWDLPVDYTKMKPR--RVDEEDPKE-------ITPEDLDPFQEALEERRYPGEVT-----IPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAK-------------RQKDGYLNGSQFSWKSVKTEG-------------MSCPTPGCDGS-------------GHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQR------ASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQVTITTMESNLKTIEEENKVIEQQNE-----------------------------------------------------SLLHELANLSQS-------------------------------LIHSLANIQLP----------------------------------------------------------------------------------------------------------------------------HMDPINEQNFDAYVTTLTEMYTNQDRYQSPE--NKALLENIKQAVRGIQV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97500-1", "uniprot_id": "MYT1L_MOUSE", "id": "P97500-1", "name": "Myelin transcription factor 1-like protein", "aln": "--------------MDVDSEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQ------PQEPAPKRKPFAVKADSSSVDECYE-----------------SDGTEDMDDKEEDDDE------------------EFSEDNDEQGDDDDEDE-VDREDEEEIEEEDDEEDDDDEDGDDVEEEEEDDDEEEEEEEEEEENEDHQMSCT--RIMQDTDKDDN-------------NNDEYDNYDELVAKS----LLNLGKIAEDAAYRARTESEMNSN------------TSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDR-------------------------SYAEGMSQ-----------------------QDSRNMNYVMLGKPMNNG-------------LMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYS--DMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMT----------KGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYGKDPSRTEKRESK-----------------------CPTPGCDGTGHVTGLYPHHR----SLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSN-------RNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPR----------------------SNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNAS---PSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYT------------HDMEAAHMAATAILNLSTRCREMPQNLSTKPQD----LCTARNPDMEVDENGTLDLSMN--KQRPRDSCCPVLTPLEPMSPQQQAVMS-----SRCFQLSEG-----DCWDLPVDYTKMKPR--RVDEDEPKE-------ITPEDLDPFQEALEERRYPGEVT-----IPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAK-------------RQKDGYLNGSQFSWKSVKTEG-------------MSCPTPGCDGS-------------GHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQR------ASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQ--ITTMESNLKTIEEENKVIEQQNE-----------------------------------------------------SLLHELANLSQS-------------------------------LIHSLANIQLP----------------------------------------------------------------------------------------------------------------------------HMDPINEQNFDAYVTTLTEMYTNQDRYQSPE--NKALLENIKQAVRGIQV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UL68-1", "uniprot_id": "MYT1L_HUMAN", "id": "Q9UL68-1", "name": "Myelin transcription factor 1-like protein", "aln": "--------------MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQ------PQEPAPKRKPFAVKADSSSVDECDD-----------------SDGTEDMDEKEEDEGE------------------EYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE---DDDEDGEDVEDEEEEE-EEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN-------------NNDEYDNYDELVAKS----LLNLGKIAEDAAYRARTESEMNSN------------TSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDR-------------------------NYADSMSQ-----------------------QDSRNMNYVMLGKPMNNG-------------LMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQHVRPEEDFPGRTPDRNYS--DMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRSEEVFDMT----------KGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKPKSSDSHVKKPYYGKDPSRTEKKESK-----------------------CPTPGCDGTGHVTGLYPHHR----SLSGCPHKDRVPPEILAMHESVLKCPTPGCTGRGHVNSN-------RNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPR----------------------SNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPS---PSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYT------------HDMEAAHMAATAILNLSTRCREMPQNLSTKPQD----LCATRNPDMEVDENGTLDLSMN--KQRPRDSCCPILTPLEPMSPQQQAVMN-----NRCFQLGEG-----DCWDLPVDYTKMKPR--RIDEDESKD-------ITPEDLDPFQEALEERRYPGEVT-----IPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAK-------------RQKDGYLNGSQFSWKSVKTEG-------------MSCPTPGCDGS-------------GHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQR------ASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQ--ITTMESNLKTIEEENKVIEQQNE-----------------------------------------------------SLLHELANLSQS-------------------------------LIHSLANIQLP----------------------------------------------------------------------------------------------------------------------------HMDPINEQNFDAYVTTLTEMYTNQDRYQSPE--NKALLENIKQAVRGIQV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PJ12-1", "uniprot_id": "M9PJ12_DROME", "id": "M9PJ12-1", "name": "", "aln": "MALSKRPLTKDTPLSESNGNHTNGNDHETSIKRRKRCSRDDDSSLINNNNNNNNNNNNNNNNNSNSNNNNLPQKKRKQGGQGHIADSPESPTCGSLPTPLAKSNTDADQDDETLIRETQAALKSLSGSWPDSRGNLYRLQEQDENPPPFQNLFEEKQKYEAIGNPSHAIQAQASSPNPNSTLFSRFHRQKENDQARLNAASGAGGVVHLEAQGRGKKTPDEDQDPELEDTSSSASGQGVYTQAASAFKPPIDIIKRNYVAAAHAHYSAYNAAAAAESAAGLAYYGYAAAAAASQQQQQQQQQHQQQQHQQLSTAFDIASQLGEKQRPKEPMADGKQYTILQPAGIGSRAASVMQDIASREGVVGVPLVATPPSTAAGSPAAAVPAAGPSTPSTPAPSYSPGSQNRVLALHEQILKCPTPGCNGRGHVQPHRSVHRSLSGCPRAVRRSGGTSRRPGAAPLAAAAADLDKHEKELHPLDKLKLASNHYLNNNNSNCINNNSSKLSGSTTMPIIKSEYSPVASIKSEYNKSPMHSYLSGEAAAPAPAAPSSASAVQAPRSGSASGATAANGENNLHAPHLSRFVGLQSPPHQPHLNPHGHHQQQQQQQQQQQQQQQQQQQQQQQQQHTLHQQRGPFIEGNDVPDPSANYHSEHQQQQQQQQQQQQADERQQQYEQMRYAQSHVSVGPSGELMAPNGGELSPGTARSAYEAHPGHPHPHPGHPHPHPPVSLSSLSSPAFTVDAVTAASGAGFERYDPSGVCCPSNGQRATAATAATAAGASAAAAAYHYLPQTTDEMQAQQQKYLQEQQLMLAKAEHEELANGGQPLYPRPMYHYDPTMGPLPPGFSAINLSVKMAAAQAAAAAAAYQNQQQQQQQQQQQQQHHQQQQQQQQQQQQQQQQQHGKQSSSPAPNVSGVPAVDLSGSTSVTSSSPHGFNSPASHNQYTAQRMGNGSPQPGASPNIASPQVPSPQGQTLDLSVTRLPHSIITSPQYGADGLVVGHAQGFVSGATGPLGPGNGGPPRSPQMEPVDFSGPPRPLGFGLVGHISGPRPYSRESTPDSGGSHYIETYRDPSGYSPHPGYGMVVQSDYPPAGYHGYGPAAYQCSNPYATAVGPGGYPTPVSGGYSPSPATCYSMPPPQHIPQHDKSKDGLTGCSRSDRNHLQSHSQELKCPTPGCDGSGHVTGNYSSHRSLSGCPRANKP----KSKPRDGQDSEPLRCPIPGCDGSGHSTGKFLSHRSASGCPIANRNKMRVLEAGGTVEQHKAAVAAATAMKFDACTTVGSQGIKKPKFDEVTMVYPKGYTGGSGLDIVMGGVGSSVGVGLGLNVGIGVTSSSSSSSSAGGNNNNSGSSNTVVTDKNPSGGGASSGANGSDDLNTLEAEISELQRENARVESQMMRLKSD--INAMESQLSTSDREASPLSGHQQQQQRSSVALASPSGQSPFASVSSTSGASSSVSGATTNSNNNNSSSGGGTTNANDLNHSISNLAPSSGSNPNQAIEGVGGAPPNANLNNYYESLRNNVITLLEHVRLPPPPPPPGAATPSSSASSVVHGLDNVCGAGGQLVAGGSLMGGEHATAYSTLLPPPPPPSSGGAASVGGMYGVGANGATGLHQGTGSSNGGGLGSSGAVGPPPVPPHHHPYTVHHPVSYAHPHGHPHAHPHPHEHFDSYISKLQSLCVPPDVYALPEDADRPVYNSVKPTMHQDYGKLMPTPI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :... . :...:: . : :: * . . :...: ..: .: . . *.:*::.*. * *:.*: * .: ..:..*: : .*. :: :*:: : : *. : ... : :. . ..: *::: . * *. * : :: :*::: * ** . .. : :. . : : .*. *: .* . * * * ** : : :.: : : :..* :.. :* :. .: :: :.: .:.. :: :*. .*** : .*: . .: * *.:: : * * * .: ...* * .*: *: . . .: ... ::.. . . : .: * : . .*. * . : * .. : ::.* : ..:*:.*.:.. .. .:: : :*. : : :: : ::: : :::: :: .:* : *:* *:: * :: : .: :: :.: .*. * ..* . . * * . .* ** . . . .....:* *. . : *.:*: :. . :** * * * :.:.. **.:: : : : *. . ** ::* : :::: :. ::: :: : * :: . : :: ::: *:.* *. * ..: *.*:.::... . .*..*:..: :: :.::.:. .*. .:*:.: *.** * . : .: . .*.*. . . : *: . . * .*:. . :. .* ..* : : * .*: ::.: . : : :*: *: ** *: *:. . * :. :. : .* . ..:* *. * : ****************:****:***********:*. .. .* :*.**:***:*****.** ***: *********:* : ::* . .: :.:.: .* * * *. .** * * : *... ::** : : **.. .:.:: **.* :..:::: *: **.**:..*:::*::*::*::: *.:***:*.* :.* . :. ::: .* *.::**: * :* * :::** * .* .::**:*::.* .: . * * ** ::.: :.:* ::: ", "identical_positions": 227, "similar_positions": 487, "identity": "13.26%" }, { "cls_id": "homologset.agr.RGD:620551", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B9EKI3-1", "uniprot_id": "TMF1_MOUSE", "id": "B9EKI3-1", "name": "TATA element modulatory factor", "aln": "MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSAWAEAIPYGEPGISPPVSGGWDTSTWGLNSTSSEPQSPPTAS-QAITKPVRRTVVDESENFFSAFLSPSDAHTIQKSPVVSKPPSKSQRPEEEVKSSLQESSSPGQSRVSETAEVR---DSVCVSGETSAVGTPSPVPEDKHEETAGEESEVKVPTVRLKASENVVNVN-TTEDVSTTSTQSLTAETKDMALEPKEQKHEDRQSNTPSPPVSSFSSGTSTTSDIEVLDHESVISESSASSRQETSDAKSSLHLMQTSFQLLSASACPEYSRLDDFQKLNESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELPGKGYALVPIIVSPSTPKTKVVESTEENAEEEEGNETLVAPSEEAELEESGRSATPVNCDQPDILASPTAGSGGHSASGPATEQCEAVENQPKAPP-EKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKEELATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENRNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERE--RAATEELLANKIQMSSVESQNTLLRQENSRLQAQLE--SEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKTLLSSQLEMERMKVEQERKKTIFTQEALKEKDHKLFSVCSTPTMSRSSSISGVDAAGLQASFLSQDESHDHSFGPMSTSASGSNLYEAVRMGAGSSIIENLQSQLKLREGEISHLQLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKN------MYKTQIDELLRQRLS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JZ48-1", "uniprot_id": "A0A0G2JZ48_RAT", "id": "A0A0G2JZ48-1", "name": "", "aln": "MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSAWAEAIPYG---ISPSVSGGWDTSTWGLNS-SSEPQSSPTAS-QAITKPVRRTVVDESENFFSAFLSPSDVQTIQKSPVVSKPPAKSQRPEEEVKSSLQEPSSPGQSRTSETAESEAT-DSACVSGETPAVGTPSPVPEGKREETASEESEGKVPTVRAKASESVVKVN-TAEDVSPTSTQSLTTETKDMALEPKEQKHEDRQSNTPSPPVSSFSSGTSTTSDIEVLDHESVISESSASSRQETSDAKSSLHLMQTSFQLLSASACPEYGRLDDFQKLSESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELPGRGYALVPIVVSPSAPKTKVVESTEENVEEEEGNETLIAPSEEAELEESGRSATPVNCDQPDTLASPTPVNVGPSASGPAAEDGEAAENHPKAPQLEQEDVGKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAERKAQLACKERDTAKKEMKTMKEELASRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNMIKKLRAKDKDNESVIAKLKKKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMNELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQETLALQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEMLEKNLSDRLGESQTLLAAAVERE--RAATEELLANKIQMSSVESQNALLRQENSRLQAQLE--SEKNKLRKLEDENSRYQVELENLKDEYVRTLEEARKEKTLLSSQLEMERMKVEQERKKTIFTQETLKEKEHKPFSVSSTPTMSRSSSLSGVDMAGLQTSFLSQDESHDHSFGPMSTSASGSNLYEAVRMGAGSSIIENLQSQLKLREGEISHLQLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDACGNPIKPYTSGARLAVLCKKTR----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P82094-1", "uniprot_id": "TMF1_HUMAN", "id": "P82094-1", "name": "TATA element modulatory factor", "aln": "MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKS-NTEPQSPPIASPKAITKPVRRTVVDESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEETVNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISESSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIVNSSTPKSKTVESAEG--KSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALS-EKEDVCKTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLLAAAVERE--RAATEELLANKIQMSSMESQNSLLRQENSRFQAQLE--SEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQDESHDHSFGPMPISANGSNLYDAVRMGAGSSIIENLQSQLKLREGEITHLQLEIGNLEKTRSIMAEELVKLTNQNDELEEKVKEIPKLRTQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKN------MYKTQIDELLRQSLS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3V2-1", "uniprot_id": "Q9W3V2_DROME", "id": "Q9W3V2-1", "name": "", "aln": "MSWF-------------EKAKTVLIEALDIQDDDS--------------------------------KAAEKDSPMAG------------------------AASDGGASPGNNATAETPGSAATPASDTPTFFDNPHAN-----------------EMVTIPPTPTSVPGSAAYGKRQ-SATSDSVDLLSSPTSPISPCGGDVPSVAKRLSESSLELITATT-----ASEVEMSPDTEPSLPDSIVIIASNDTSDNAEGDGEDDDDEGTQLKRHMEDHLNDSTKTMKALVLSDIQVAGNADSD---------------STQSFEDIQLQMSHKGKSPAPAKTGTVDQSYSSTSSDIEIISNPNGDSS---------------------------------TNSTTTRTSPQKFKELAGGKVCLKAKGHHREPSEISLLSEDSQS-ELDKLVQRISELNQVIEAREQRLLQSERQNAELLERNQELRARVEAAANSANSPD--AADAVQRLSALEKKFQASIRERDALRIQMKSLRDELQNKIPR----DELAECNEMIAALQSEGEKLSKEILQQSTIIKKLRAKEKTSDTLLKKNGEQISLLSSESERLKRSLAAKEEMERTQIEAVCRMTAEKKRVDEENAESRSRIEDLQSRLAALQASFD-----------------------GLKGDLQKRTRLE------QDSLRAEHQEYVQQVSDLREKLRLAEHSLARREQQMREENRQLMRRLEAAELRAESSTQELGATTTPLIRQIESLQRTLDQRSAAWNREEQQLLQKLDDSQVQLRSLQQLESVQGEKQELLRTRCGLLEEKLSSALMEAEAAKMALRQHDLEAANKENDHKKQLSLLQEEIQQQQERIASLEQLCQRQKEEEEQRKQPTLLTVKAVKASSELQPQLQMQLPKSQAPLRSSPPLSLVD-DSGSNEEALGGMIDWQADDLDCASNSGRQQSGIIQGVHLSFLAANTTTFEHLQALLKQRDGELTHLQWEVSRLQAERSVLDAEISNLTIELETMKEKQQMYEVMEKGYEDLQHRYDALLQMYGEKVERTEELELDLTELKA------AYKLQIDELLAAPPPNLQRPSKQT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47166-1", "uniprot_id": "SGM1_YEAST", "id": "P47166-1", "name": "Protein SGM1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKKLSLEERLSLATKK-----GRKKNKRSTSNLSSPSPVVLSNNEQESARTSIDDAAAGVVSIDNAENIDDPAVRSESTVEGDTG-----------------------------------------KADSIAVDDVVHPDHNRTDCFDDTMVSLPTWLPKN------------------------------------YTEFTVEELVKEISP---------------------------EYLRLNKQIDDLTNELN-RKSQIETTDSSFFKLIKEKDDLIDQLRKEGAKLAETELRQSNQIKALRTKVKDLEYEVSELNDSSAQSVENYNELQSLYHN-------------IQGQLAEATNKLKDADKQKESLETLEKNIKEKDDLITILQQSLDNMRTLLE--KEKSEFQTEKKALQEATVDQVTTLETKLEQLRIELDSSTQNLDAKSNRDFVD--------------------------------------------DQQSYEEKQHASFQYNRLKEQLESSKANWDSIEYALNTKIVNLENRFESTMKEKN----DIEEKYQTALRSSETLGKQLEKEKENHSKAVLEVKDLERRAETLKSSLQSIS----DDYNLLKKKYEIQRSQ-----LEQKENELKPHQE----NSNEKIIDKIPVELTDSLNSMEGNIEDEWTLPQENSMLSLSMSKLGELESDPSLKPIYNESHETICSEESQHFDRKNVDFSIDD----IPEEAAALQAIREGESMNSLNNTSIPYRRASVQLSNSNGHISAHLVNKLSTELKRLEGELSASKELYDNLLKEKTKANDEILRLLEENDKFNEVNKQKDDLLKRVEQMQSKLETSLQLLGEKTEQVEELENDVSDLKE------MMHQQVQQMVEMQGKMR-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* . ::: . : : : . *.. * .. * :. : : : : .::. . .* : . *. : . .. . : . . : * : : :. *.: :: *: :: . . * : ::* .: . . . : : : :. : * : : :** . * . *. : *: ::. ::.*. : * .: :: .. . : : :. : * : : : ::.: : :: . ::*: : . ::. ::: * . *: *. :: * :. : :* .*:: : . : .: . . :*. *.* * ... . .: : ::. : . . :** .: : : :. : .: : . .. .. .::. : . :.:. . : : . . .. .. :* . . : :. : .. .: .::*.: ** :**:: : ..* :: *: .* : : ::* : : .::: : :: **: ***.*..***. *: : :: : ", "identical_positions": 53, "similar_positions": 235, "identity": "4.75%" }, { "cls_id": "homologset.agr.RGD:620552", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHE8-1", "uniprot_id": "NINJ2_RAT", "id": "Q9JHE8-1", "name": "Ninjurin-2", "aln": "MESDREIIHLQHRHSTPGGNQRHINLNHYATKKSVAESMLDVALFMSNAMRLKSVLEQGPFSQYYTTLLTLISASLLLQVVIGILLVVIARLNLNEVENQWRLNQLNNAATTLVFITVVINIFITAFGAHKTG---SVAARTSSNPI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL89-1", "uniprot_id": "NINJ2_MOUSE", "id": "Q9JL89-1", "name": "Ninjurin-2", "aln": "MESDRETIHLQHRHSMRGGNQR-IDLNFYATKKSVAESMLDVALFMSNAMRLKSVLQQGPFAEYYTTLVTLIIVSLLLQVVISLLLVFIAILNLNEVENQRHLNKLNNAATILVFITVVINIFITAFGAHHAA---SMAARTSSNPI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZG7-1", "uniprot_id": "NINJ2_HUMAN", "id": "Q9NZG7-1", "name": "Ninjurin-2", "aln": "MESARENIDLQPGSSDPR-SQP-INLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTG---FLAARASRNPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8JQY7-1", "uniprot_id": "A8JQY7_DROME", "id": "A8JQY7-1", "name": "", "aln": "MASGLQRVNEN--------EMKAMDANRYATKKTIAQGMLDIALLTANASQLKYILQVGEQHQFYKLMLILISLSIVMQLLVGILFVVIGSLNINRQQDQTAAVILNDVILVVVFIISVVNVIISGFGIEYSSQPLRLLDQHEKTP-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : :. : . :: * *****::*:.***:**: :** :** :*: * .:*. :: ** *:::*:::.:*:*.*. **:*. :.* **:. :**: *:*::*:.** . :. : : . .* ", "identical_positions": 42, "similar_positions": 53, "identity": "28.57%" }, { "cls_id": "homologset.agr.RGD:620553", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q0N2-1", "uniprot_id": "PTPRH_MOUSE", "id": "E9Q0N2-1", "name": "Receptor-type tyrosine-protein phosphatase H", "aln": "--MARAGGNCGVWRSLVLLGLYGCSVVRAAG----------------------------------------------------TSVTVDRHAPASSYEFSMWVEKDGVSSSPQIPVTTAAPNPVRNLRVEGQNNISISLSWEPPDQSSLQGLTYWTQCSRHGGQTETRNTTDTSVTVDGLDPGSSYECSVWVEKDGLYSKNETLNTSTAPNPVRNLRVEGQNNISISLSWEPPDQPSLQGLTYWAQCSRHGGQTETRNTADTSVTVDGLDPGSSYECSVWVEKDGVYSTNETLNTSTAPNPVRNLRVEGQNNISISLSWEPPDQPSLQGLTYWAQCSRHGGQTETRNTTDTSITVDGLDPGSSYECSVWVEKDGVYSTNETLSNTTAPNPVRNLRVKSQNNFSISLSWEPPDQPSLQGLIYWAQCSRHGGQTETRNTTDTSVTVDGLDPGFLYKCSVWVEKDGVYSTNETLNTSTVP--------------------------------------------------------------------------------------ISASNPVRNLRVEGQNN---FSISLSWEPPDQSSLQGLTYWAQCSRHG----GQ-------TETRNTADTSVTVDGLDPGSSYECSVWVEKDGVYSTNETLNTSTVPAAVNITSCISTSGGYGVLLTWSCPSGGYESFEVKVGRK-WRSENGSLCGKGVTVSDLEPAQSYTATVTTVFKDLKAQSLSTTCHTESAAIIAGAIVGILLLFILVGLLIVFLKRRRKKRQPKEVPKDLVCSCP--GDILAKDFADHVRENEKDSNCGFAEEYQQLALEGQGQSQITASALENRSKNRYRNVLPYDWSRVPLQPLQEEPGSDYINASFMPGLWSP-KEFIATQGPLPNTVGDFWRMVWEQQSHTLVMLTNCMESGRVKCEHYWPLDAQPCIHGQLQVMLISEEASENWTVRHLQLFHMKEQQTLSLRQFHYLAWPDHGVPYSPDPLLAFRKMLRQWMDQTTDGGPPIVHCSAGVGRTGTLIALDVLLRQLECEGLVGPFSFVKKMRESRPLMVQTEAQYVFLHQCILKSLQKPAPALVPEEAMYENVASLVYENASAIMAHESEFSASGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K754-1", "uniprot_id": "A0A0G2K754_RAT", "id": "A0A0G2K754-1", "name": "Receptor-type tyrosine-protein phosphatase H", "aln": "--MARAGGNCGVWGSLVLLGLCGCSVVRTAG----------------------------------------------------TRVTVDRLAPASSYEFSVWAEKDGVSGSPQTLIATTAPNPVRNLRVEGQNTTSISLSWDPPENSSSQDLTYWAQCIRYDGQNETRHTKDTRVSVDGLDPGTSYECSVRVEKDGVYSTWETKNTTTAPNPVRNLRVEGQNTTSISLSWDPPENSSSQDLTYWAQCIRYDGQNETRHTKDTRVTVDGLDPGTSYECSVRVEKDGVYSTWETKNTTTASNPVRNLTVEGQNTTAISLSWDPPENSSSQDLTYWAQCIGYDGKNETRHTKDTRVTVDGLDPGTSYECSVRVEKDGVYSTWETKNTTTAPNPVRNLRVEGQNTTAISLSWDPPENSSSQDLTYWAQCIGYDGKNETRHTKDTRVTVDGLDPGTSYECSVRVEKDGVYSTWETKNTTTVP--------------------------------------------------------------------------------------ISAPNPVRNLRVEGQNT---TSISLSWDPPENSSSQDLTYWAQCIRYD----GQ-------NETRHTKDTRVSVDGLDPGTSYECSVRVEKDGVYSTWETKNTTTVPAAVNITSCISTSGGYGIILTWSCPSGSYETFEVEVGRK-WSSQNGSLCGKGMTVLDLEPAQSYTATVTTVSNSLKVQSAPATCRTESTAVIAGAIVGILLLFILVGLLIVFLKRRRKKQQPKEVPKDLVFRFP--GDILAKDFADHVRENEKDSNCGFAEEYQQLALEGQGQSQMTALALENVSKNRYRNVLPYDWSRVPLQPLHEEPGSDYINASFMPGLWSP-KEFIATQGPLPHTVSDFWRMVWEQQSHTLVMLANCMESGQVKCEHYWPLDAQPCTHGQLQVTLVSEEVTENWTVRHLQLFHMKEQQTLSVRQFHYVAWPDHGVPYSPDPLLAFQKLLRQWLDQTMDGGPPIVHCSAGVGRTGTLIALDVLLRQLECEGLVDPFSFVKKMRESRPLMVQTEAQYVFLHQCILRSLQKPDPALPAKEATYENVASLVYENASAIRAHESEVSASGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HD43-1", "uniprot_id": "PTPRH_HUMAN", "id": "Q9HD43-1", "name": "Receptor-type tyrosine-protein phosphatase H", "aln": "--MAGAGGGLGVWGNLVLLGLCSWTGARAPAPNPGRNLTVETQTTSSISLSWEVPDGLDSQNSNYWVQCTGDGGTTETRNTTATNVTVDGLGPGSLYTCSVWVEKDGVNSSVGTVTTATAPNPVRNLRVEAQTNSSIALTWEVPDGPDPQNSTYGVEYTGDGGRAGTRSTAHTNITVDGLEPGCLYAFSMWVGKNGINSSRETRNATTAHNPVRNLRVEAQTTSSISLSWEVPDGTDPQNSTYCVQCTGDGGRTETRNTTDTRVTVDGLGPGSLYTCSVWVEKDGVNSSVEIVTSATAPNPVRNLTVEAQTNSSIALTWEVPDGPDPQNSTYGVEYTGDGGRAGTRSTAHTNITVDRLEPGCLYVFSVWVGKNGINSSRETRNATTAPNPVRNLHMETQTNSSIALCWEVPDGPYPQDYTYWVEYTGDGGGTETRNTTNTSVTAERLEPGTLYTFSVWAEKNGARGSRQNVSISTVPNAVTSLSKQDWTNSTIALRWTAPQGPGQSSYSYWVSWVREGMTDPRTQSTSGTDITLKELEAGSLYHLTVWAERNEVRGYNSTLTAATAPNEVTDLQNETQTK---NSVMLWWKAPGDPHSQLYVYWVQWASKGHPRRGQDPQANWVNQTSRTNETWYKVEALEPGTLYNFTVWAERNDVASSTQSLCASTYPDTVTITSCVSTSAGYGVNLIWSCPQGGYEAFELEVGGQ-RGSQDRSSCGEAVSVLGLGPARSYPATITTIWDGMKVVSHSVVCHTESAGVIAGAFVGILLFLILVGLLIFFLKRRNKKKQQKPELRDLVFSSP--GDIPAEDFADHVRKNERDSNCGFADEYQQLSLVGHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSP-QEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFLQQSAQAPAEKEVPYEDVENLIYENVAAIQAHKLEV-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YYB8-1", "uniprot_id": "A0A8M6YYB8_DANRE", "id": "A0A8M6YYB8-1", "name": "protein-tyrosine-phosphatase", "aln": "MELVLAFALLCVLSVSGQATLPDVNDVRITHRTETELTFQWDKAGGSNSYSYILRRD------------GIDSDIITAGTVNQVTYKVSDLSSGTNYNWTLFTVFGDQRSEGKNFSAATVPPNVESVSVIDQSETTITLQWKKDKAEYSYNLTYGDKVDTP-----PSPQSTVEYTVTSLSPGTNYSFTLYTVFEGLKSSGFSFFAVTVPPNVESVSVIDQSETTITLQWKKDKAEYSYNLTYEDKVQTP-----SSPQSPVEYTVTSLSPGTKYTFTLYTVFEGLKSSGFSFSAVTVPSKITGFSVIGRSETALTFQWTK----EKDEYTYELDKSDANTQISFTDTTVVCLITS-LSPGTEYSYNLYAVFEGVKSQAKGISEVTVPSNVENVSVVEANDTDVILQWNAVPNEQNK-YNYILKYNDVEESVDFTTENEIKHHVSGLIPATNYNFTLHTEFYSQNSTGYNFNHTTFLSSVTEVRVNRSLTELTVEWNKLNQNNVYNYTLLRSDGAEIDFTGSAVVG-----------------DVIKHKYSSLKPGTVYSFTLFTVSNNVRSSEHSFKSITALDCASFNWKVTNTSIVADVYGCTYVTAQNSSGSGK---------NASIEGDKVNLRDLYPGESYTVSLFYNLESKMLTQCSQRLTLVPYVVSNLKCEYHSGGYGLAVMWDYPDGVVDVVEVDVNKKSFNHSHGSDEPTQQLVTGLQAAQWYKVKATSFSGARRSETILINCQTDPAGVIAGVLVFFLLVIIICAGVFVWFRYKSARNNGPDASADLKVSKKNYKTIACDKFPEHFRNMSRDDNRAFSAEYDDLSSVGVEQSKVAALLPENKDKNRFSNVLPYDTSRVHLT-INKAGDSDYINANYMPGYGNASREYIAAQGPLPSTVNDFWRMIWEKKSSTIVMVTNCTEGGRVKCEQYWPLDYTPCLYENLLVTVKSENKSQSWTLREFNVKNKMTSETRTVRHFHFTAWPDHGVPRGTEELIQFRDLIRQHIESHFSTGPTVVHCSAGVGRTGTLIALDVLLQQLNREKAVGVAAFVQEMRLNRPLMVQTESQYVFLHQCILDSLQT---KFVQQSEPIYQNTDTIYVNAMALKDFENSSHT---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * . * * . . .* . . .*. ...: * :::. .. .. :::.* *..: * *. :*:* *. . . ** : . . :* .*.** * :: . :*: *. : : *. *..: * *. :*:*.*. . . ** : : . ** .*.**: * :: . :*: *: .: *... : .: * .:. :::: * . : ** : . : * . : .. *.** * .: . :*: * : . .*.*. *.*: : . : * *: : * : : .: .. * *. * :: .* . .: . . :*. :..* * . . . :. . : *. . . . . *: . .: * ** * :: : :. : : : * .*. .* *.***: : *. *.* : .*:.*. : .. * * .* .*: * .. *:. : : *:*:.:.:***.:* :**.:*: . ::.::: : :.: ** * ...*.:*.*: .:*.* .*: **::*: * **::.* ** ***: ****** *** * ::: .******.:*** .. :*:**:***** **.****::**::* *:**::** *.*:****:***** ** : :* * : .*: :.**:*.: : : .:* ::*:**: ******** ..: *: * ::** ::. . **.:********************:**: * :. :**::** .********:********** ** :. : . :* *. *: .: . ", "identical_positions": 247, "similar_positions": 296, "identity": "21.88%" }, { "cls_id": "homologset.agr.RGD:620554", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38060-1", "uniprot_id": "HMGCL_MOUSE", "id": "P38060-1", "name": "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "aln": "----MASVRKAFPRRLVGLTSLRAVSTSSMGTLPKQVKIVEVGPRDGLQNEKSIVPTPVKIRLIDMLSEAGLPVIEATSFVSPKWVPQMADHSDVLKGIQKFPGINYPVLTPNMKGFEEAVAAGAKEVSVFGAVSELFTRKNANCSIEESFQRFAGVMQAAQAASISVRGYVSCALGCPYEGKVSPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGLMKDMLTAVMHEVPVTALAVHCHDTYGQALANTLVALQMGVSVVDSSVAGLG---GCPYAKGASGNLATEDLVYMLNGLGIHTGVNLQKLLEAGDFICQALNRKTSSKV-------AQATCKL------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97519-1", "uniprot_id": "HMGCL_RAT", "id": "P97519-1", "name": "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "aln": "----MATVRKAFPQRLVGLASLRAASTSSMGTLPKRVKIVEVGPRDGLQNEKSIVPTPVKIKLIDMLSEAGLPVIEATSFVSPKWVPQMADHSDVLKGIQKFPGINYPVLTPNMKGFEEAVAAGAKEVSIFGAASELFTRKNVNCSIEESFQRFDGVMQAARAASISVRGYVSCALGCPYEGKVSPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGLMKDMLTAVLHEVPVAALAVHCHDTYGQALANTLVALQMGVSVVDSSVAGLG---GCPYAKGASGNLATEDLVYMLTGLGIHTGVNLQKLLEAGDFICQALNRKTSSKV-------AQATCKL------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35914-1", "uniprot_id": "HMGCL_HUMAN", "id": "P35914-1", "name": "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "aln": "----MAAMRKALPRRLVGLASLRAVSTSSMGTLPKRVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIETTSFVSPKWVPQMGDHTEVLKGIQKFPGINYPVLTPNLKGFEAAVAAGAKEVVIFGAASELFTKKNINCSIEESFQRFDAILKAAQSANISVRGYVSCALGCPYEGKISPAKVAEVTKKFYSMGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLG---GCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKV-------AQATCKL------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM58-1", "uniprot_id": "Q9VM58_DROME", "id": "Q9VM58-1", "name": "hydroxymethylglutaryl-CoA lyase", "aln": "-------MISAPIRSILALTAKRTAVTSAAN----QVRIVEVGPRDGLQNEPKLLPAATKIELINQLSETGLRTIEATSFVSAKWVPQMGDNAEVLKGIRKVTGISYPVLTPNLKGFESALEAGAEEVAVFGAASDAFSLKNVNCTAAEAIERFKPVLKAAQKHGVRVRGYVSTVVGCPYEGAVAPSAVVKVVEALYQMGCYEISLGDTIGVGTPGTMRRMLDEVTKVVPAKDLAVHCHDTYGQALSNILVSLDYGIRVVDSSVSGLG---GCPYAKGASGNAATEDVVYLLHGMGLDTGVNLDKLIQVGRYICTELGRTSESKVNRAWKG-PQARVK-------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12122-1", "uniprot_id": "HOSM_YEAST", "id": "Q12122-1", "name": "Homocitrate synthase, mitochondrial", "aln": "MSENNEFQSVTESTTAPTTSNPYGPNPADYLSNVKNFQLIDSTLREGEQFANAFFDTEKKIEIARALDDFGVDYIELTSPVASEQSRKDCEAICKLG----LKAKILTHIRCHMDDARVAVETGVDGVDVVIGTSKFLRQYSHGKDMNYIAKSAVEVIEFVKSKGIEIR------FSSEDSFRSDLVDLLNIYKTVDKIGVNRVGIADTVGCANPRQVYELIR-TLKSVVSCDIECHFHNDTGCAIANAYTALEGGARLIDVSVLGIGERNGITPLGGLMARMIVAAPDYVRSKYKLHKIRDIENLVADAVEVNIPFNNPITGFCAFTHKAGIHAKAILANPSTYEILDPHDFGMKRYIHFANRLTGWNAIKSRVDQLNLNLTDDQIKEVTAKIKKLGDVRPLNIDDVDSIIKDFHAELSTPLLKPVNKG--TDDDNIDISNGHVSKKAKVTK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P48570-1", "uniprot_id": "HOSC_YEAST", "id": "P48570-1", "name": "Homocitrate synthase, cytosolic isozyme", "aln": "--------------MTAAKPNPYAAKPGDYLSNVNNFQLIDSTLREGEQFANAFFDTEKKIEIARALDDFGVDYIELTSPVASEQSRKDCEAICKLG----LKAKILTHIRCHMDDAKVAVETGVDGVDVVIGTSKFLRQYSHGKDMNYIAKSAVEVIEFVKSKGIEIR------FSSEDSFRSDLVDLLNIYKTVDKIGVNRVGIADTVGCANPRQVYELIR-TLKSVVSCDIECHFHNDTGCAIANAYTALEGGARLIDVSVLGIGERNGITPLGGLMARMIVAAPDYVKSKYKLHKIRDIENLVADAVEVNIPFNNPITGFCAFTHKAGIHAKAILANPSTYEILDPHDFGMKRYIHFANRLTGWNAIKARVDQLNLNLTDDQIKEVTAKIKKLGDVRSLNIDDVDSIIKNFHAEVSTPQVLSAKKNKKNDSDVPELATIPAAKRTKPSA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. ..:::: *:* * :. : **.: *.: *: ** ** *:.: : : * . . . : ::.. . *: :*.. * :. ..*. : . . : ::: .: .: :* ... . : :: : . .:* .:.:.**:* ..* : :: . : * : * *: * *::* :*: * ::* ** *:* * . * .. . *: :.. ::::*: . : :.. . :* ", "identical_positions": 41, "similar_positions": 106, "identity": "9.05%" }, { "cls_id": "homologset.agr.RGD:620555", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P03889-1", "uniprot_id": "NU1M_RAT", "id": "P03889-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "------MYFINILTLLIPILIAMAFLTLVERKILGYMQLRKGPNIVGPYGILQPFADAMKLFMKEPMRPLTTSMSLFIIAPTLSLTLALSLWIPLPMPHPLINLNLGMLFILATSSLSVYSILWSGWASNSKYSLFGALRAVAQTISYEVTMAIILLSVLLMSGSFSLQMLITTQEHIWLLIPAWPMAMMWYISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYTNIILMNALTSIVFLGPLYHINYPELYSTSFMTETLLLSTTFLWIRASYPRFRYDQLMHLLWKNFLPLTLAFCMWYISLPIFLAGIPPYT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03888-1", "uniprot_id": "NU1M_MOUSE", "id": "P03888-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "------MFFINILTLLVPILIAMAFLTLVERKILGYMQLRKGPNIVGPYGILQPFADAMKLFMKEPMRPLTTSMSLFIIAPTLSLTLALSLWVPLPMPHPLINLNLGILFILATSSLSVYSILWSGWASNSKYSLFGALRAVAQTISYEVTMAIILLSVLLMNGSYSLQTLITTQEHMWLLLPAWPMAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYTNIILMNALTTIIFLGPLYYINLPELYSTNFMMEALLLSSTFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWHISLPIFTAGVPPYM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03886-1", "uniprot_id": "NU1M_HUMAN", "id": "P03886-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "------MPMANLLLLIVPILIAMAFLMLTERKILGYMQLRKGPNVVGPYGLLQPFADAMKLFTKEPLKPATSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILWSGWASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMSGSFNLSTLITTQEHLWLLLPSWPLAMMWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMNTLTTTIFLGTTYDALSPELYTTYFVTKTLLLTSLFLWIRTAYPRFRYDQLMHLLWKNFLPLTLALLMWYVSMPITISSIPPQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIZ0-1", "uniprot_id": "NU1M_DANRE", "id": "Q9MIZ0-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "MLDILTSHLINPLAYAVPVLIAVAFLTLVERKVLGYMQLRKGPNVMGPRGLLQSVADGVKLFIKEPIRPSMASPILFLTAPVLALILAMMLWAPMPMPYPVLDLNLGILFIMAISSLAVYSILGSGWASNSKYALIGALRAVAQTISYEVSLGLILLSAVIFSGGYTLQTFNTTQEDTWLLLPLWPLAIMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYSNILLMNTHSTVLFLGASFTPDAPELMTISIATKTAMLSILFLWMRASYPRFRYDQLMHLIWKNFLPITLVLVLWHIALPIALAGLPPQT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18929-1", "uniprot_id": "NU1M_DROME", "id": "P18929-1", "name": "NADH-ubiquinone oxidoreductase chain 1", "aln": "--MEFILSLIGSLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLMGIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFVKLYSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYEVSLALILLSFIFLIGSYNMIYFFFYQVYMWFLIILFPMALVWMSISLAETNRTPFDFAEGESELVSGFNVEYSSGGFALIFMAEYASILFMSMLFCVIFLG-------CDVFNLLFYMKLTFISFVFIWVRGTLPRFRYDKLMYLAWKCFLSFSLNYLLFFIGFKILLFSLL---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : :*:::*** * ***:***:*:***** :* *: *...*.:*** ** * :. : :* ::* ::: :* :*: : .:*** **::. :**.**::: :**:***:*:*:*.************::.:**** ::: *.:.: : * *:*: :*:*::* :******:***::***********:**::* ***:*:***:.*::*. :*** :: . : : ::: *:*:* : ******:**:* ** **.::* ::.:.: * .: ", "identical_positions": 125, "similar_positions": 103, "identity": "38.58%" }, { "cls_id": "homologset.agr.RGD:620556", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11662-1", "uniprot_id": "NU2M_RAT", "id": "P11662-1", "name": "NADH-ubiquinone oxidoreductase chain 2", "aln": "-MNPITLIIIYFTILMGPVITMSSSNLLLMWVGLEMSLLAIIPLLANKKSPRSTEAATKYFLTQATASMIILLVIILNYKQSGMWTLQQQTNNMLLNMMLISLAMKLGLAPFHYWLPEVTQGIPLHIGLILLTWQKIAPLSILYQFYQLLNPTITTILAISSVFVGAWGGLNQTQTRKIMAYSSIAHMGWMTAILPYNPNLTLLNLTIYILLTVPMFITLMTNSATTINTLSLAWNKTPMILTMTSIILLSLGGLPPLTGFLPKWAIISELLKNNCSTLSTLMAIMALLSLFFYTRLIYSMSLTMFPTNNNSKMISHHHQNPKHNFILPTLTVLSTLTLPLSSQLIT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03893-1", "uniprot_id": "NU2M_MOUSE", "id": "P03893-1", "name": "NADH-ubiquinone oxidoreductase chain 2", "aln": "-MNPITLAIIYFTIFLGPVITMSSTNLMLMWVGLEFSLLAIIPMLINKKNPRSTEAATKYFVTQATASMIILLAIVLNYKQLGTWMFQQQTNGLILNMTLMALSMKLGLAPFHFWLPEVTQGIPLHMGLILLTWQKIAPLSILIQIYPLLNSTIILMLAITSIFMGAWGGLNQTQMRKIMAYSSIAHMGWMLAILPYNPSLTLLNLMIYIILTAPMFMALMLNNSMTINSISLLWNKTPAMLTMISLMLLSLGGLPPLTGFLPKWIIITELMKNNCLIMATLMAMMALLNLFFYTRLIYSTSLTMFPTNNNSKMMTHQTKT-KPNLMFSTLAIMSTMTLPLAPQLIT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03891-1", "uniprot_id": "NU2M_HUMAN", "id": "P03891-1", "name": "NADH-ubiquinone oxidoreductase chain 2", "aln": "-MNPLAQPVIYSTIFAGTLITALSSHWFFTWVGLEMNMLAFIPVLTKKMNPRSTEAAIKYFLTQATASMILLMAILFNNMLSGQWTMTNTTNQYSSLMIMMAMAMKLGMAPFHFWVPEVTQGTPLTSGLLLLTWQKLAPISIMYQISPSLNVSLLLTLSILSIMAGSWGGLNQTQLRKILAYSSITHMGWMMAVLPYNPNMTILNLTIYIILTTTAFLLLNLNSSTTTLLLSRTWNKLTWLTPLIPSTLLSLGGLPPLTGFLPKWAIIEEFTKNNSLIIPTIMATITLLNLYFYLRLIYSTSITLLPMSNNVKMKWQFEHT-KPTPFLPTLIALTTLLLPISPFMLMIL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY9-1", "uniprot_id": "NU2M_DANRE", "id": "Q9MIY9-1", "name": "NADH-ubiquinone oxidoreductase chain 2", "aln": "-MNPYVLMILMSSLGLGTTLTFSSSHWILAWMGLEINTLAIVPLMAQQHHPRAVEATTKYFLIQAAAAAMILFTSTTNAWISGQWDVTGMPGPATSTAMMFALALKIGLAPMHFWLPEVLQGLDLLTGLILSTWQKLAPMALIIQTTQTTDPLILTSLGIASSLIGGWSGLNQTQLRKILAYSSIAHMGWMIIVIQYAPQLTLIALGTYIFMTSAAFLTLKVLSATKINTLTTTWPKSPILAAIATLVMLSLGGLPPLTGFMPKWLILQELTKQDLPATATIMALTALLSLFFYLRLCHAMTLTTSPNTINSAPHWRVQTT-QNSLPLTISVTVTMGLLPLTPAILMLTT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P03896-1", "uniprot_id": "NU2M_DROME", "id": "P03896-1", "name": "NADH-ubiquinone oxidoreductase chain 2", "aln": "MFNNSSKILFITIMIIGTLITVTSNSWLGAWMGLEINLLSFIPLLSDNNNLMSTEASLKYFLTQVLASTVLLFSSILLMLKNNMNNEINES--FTSMIIMSALLLKSGAAPFHFWFPNMMEGLTWMNALMLMTWQKIAPLMLISYLN---IKYLLLISVILSVIIGAIGGLNQTSLRKLMAFSSINHLGWMLSSLMISESIWLIYFFFYSFLSFVLTFMFNIFKLFHLNQLFSWFVNSKILKFTLFMNFLSLGGLPPFLGFLPKWLVIQQLTLCNQYFMLTLMMMSTLITLFFYLRICYSAFMMNYFENNWIMKMNMNSINYNMYMIMTFFSIFGLFLISLFYFMF----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :: : *. :* *. : *:***:. *:::*:: .: :.**: ***: *. *: ::*: . . : :: :* * **:*:*.*:: :* .*:* ****:**: :: : * * : *. .*****. **::*:*** *:*** : .: :: : * ::: : : . : : : : :********: **:*** :: :: : *:* :*:.*:** *: :: : . . : :. . :.: :: ", "identical_positions": 73, "similar_positions": 98, "identity": "20.86%" }, { "cls_id": "homologset.agr.RGD:620557", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05506-1", "uniprot_id": "NU3M_RAT", "id": "P05506-1", "name": "NADH-ubiquinone oxidoreductase chain 3", "aln": "-MN-LLIIITINITLSFILISIAFWLPQMNLYSEKANPYECGFDPTSSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQTTNTTTMMATAFILVTILALGLSYEWTQKGLEWTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03899-1", "uniprot_id": "NU3M_MOUSE", "id": "P03899-1", "name": "NADH-ubiquinone oxidoreductase chain 3", "aln": "-MN-LYTVIFINILLSLTLILVAFWLPQMNLYSEKANPYECGFDPTSSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQTIKTSTMMIMAFILVTILSLGLAYEWTQKGLEWTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03897-1", "uniprot_id": "NU3M_HUMAN", "id": "P03897-1", "name": "NADH-ubiquinone oxidoreductase chain 3", "aln": "-MN-FALILMINTLLALLLMIITFWLPQLNGYMEKSTPYECGFDPMSPARVPFSMKFFLVAITFLLFDLEIALLLPLPWALQTTNLPLMVMSSLLLIIILALSLAYEWLQKGLDWTE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY3-1", "uniprot_id": "NU3M_DANRE", "id": "Q9MIY3-1", "name": "NADH-ubiquinone oxidoreductase chain 3", "aln": "-MNLFATILIIMTTLSLVLALVSFWLPQMNSDTEKLSPYECGFDPLGSARLPFSLRFFLVAVLFPLFDLEIALLLPLPWGDQLNNPMETLFWAMTVLILLTLGLAYEWAQGGLEWAE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18930-1", "uniprot_id": "NU3M_DROME", "id": "P18930-1", "name": "NADH-ubiquinone oxidoreductase chain 3", "aln": "MFSIIFIALLILLITTIVMFLASILSKKALIDREKSSPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPMIIIMKYSNIMIWTITSIIFILILLIGLYHEWNQGMLNWSN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : * :: : :: : ** .*:****** ..:*:***::***::: * :**:****:**: : : :: .: :* :.* :** * *:*::", "identical_positions": 33, "similar_positions": 38, "identity": "28.21%" }, { "cls_id": "homologset.agr.RGD:620558", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56395-1", "uniprot_id": "CYB5_MOUSE", "id": "P56395-1", "name": "Cytochrome b5", "aln": "MAGQSDKDVKYYTLEEIQKHKDSKSTWVILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDARELSKTYIIGELHPD-DRSKIAKPSD-TLITTVESNSSWWTNWVIPAISALAVALMYRLYMAED--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00173-1", "uniprot_id": "CYB5_RAT", "id": "P00173-1", "name": "Cytochrome b5", "aln": "MAEQSDKDVKYYTLEEIQKHKDSKSTWVILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDARELSKTYIIGELHPD-DRSKIAKPSE-TLITTVESNSSWWTNWVIPAISALVVALMYRLYMAED--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00167-1", "uniprot_id": "CYB5_HUMAN", "id": "P00167-1", "name": "Cytochrome b5", "aln": "MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPD-DRPKLNKPPE-TLITTIDSSSSWWTNWVIPAISAVAVALMYRLYMAED--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V4N3-1", "uniprot_id": "CYB5_DROME", "id": "Q9V4N3-1", "name": "Cytochrome b5", "aln": "---MSSEETKTFTRAEVAKHNTNKDTWLLIHNNIYDVTAFLNEHPGGEEVLIEQAGKDATENFEDVGHSNDARDMMKKYKIGELVES-ERTSVAQKSEPTWSTEQQTEESSVKSWLVPLVLCLVATLFYKFFFGGAKQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40312-1", "uniprot_id": "CYB5_YEAST", "id": "P40312-1", "name": "Cytochrome b5", "aln": "-------MPKVYSYQEVAEHNGPENFWIIIDDKVYDVSQFKDEHPGGDEIIMDLGGQDATESFVDIGHSDEALRLLKGLYIGDVDKTSERVSVEKVST-------SENQSKGSGTLVVILAILMLGVAYYLLNE----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: *: :*: :. *:::..::**:: * :*****:*:: : .* ****.* *:*** :* : * **:: :* .: : . . ..* .. :: : : : * : ", "identical_positions": 30, "similar_positions": 44, "identity": "21.74%" }, { "cls_id": "homologset.agr.RGD:620559", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05508-1", "uniprot_id": "NU4M_RAT", "id": "P05508-1", "name": "NADH-ubiquinone oxidoreductase chain 4", "aln": "MLKIIFPSIMLLPLTWLSANKKIWTNVTSYSFLVSLLSLSLLWQNDENYLNFS-VMFSSDPLSTPLIILTTWLLPLMMLASQNHMKKENMMHQKLYISMLISLQILLIMTFSATELILFYILFEATLIPTLIIITRWGNQTERLNAGIYFLFYTLIGSIPLLIALISIQNSMGTLNFLILSLTTHPLPSTWSNTILWLACMMAFMIKMPLYGVHLWLPKAHVEAPIAGSMILAAILLKLGGYGMMRVSIILDPLTKSLAYPFIILSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVITAIMIQTPWSFMGATMLMIAHGLTSSLLFCLANTNYERIHSRTMIMARGLQMIFPLMATWWLLASLANLALPPLINLMGELFIVMATFSWSNPSIILMATNIVITGIYSMYMIITTQRGKLTSHMNNLQPSHTRELTLMALHIIPLMLLTINPKLITGLTM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03911-1", "uniprot_id": "NU4M_MOUSE", "id": "P03911-1", "name": "NADH-ubiquinone oxidoreductase chain 4", "aln": "MLKIILPSLMLLPLTWLSSPKKTWTNVTSYSFLISLTSLTLLWQTDENYKNFS-NMFSSDPLSTPLIILTAWLLPLMLMASQNHLKKDNNVLQKLYISMLISLQILLIMTFSATELIMFYILFEATLIPTLIIITRWGNQTERLNAGIYFLFYTLIGSIPLLIALILIQNHVGTLNLMILSFTTHTLDASWSNNLLWLACMMAFLIKMPLYGVHLWLPKAHVEAPIAGSMILAAILLKLGSYGMIRISIILDPLTKYMAYPFILLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIASIMIQTPWSFMGATMLMIAHGLTSSLLFCLANSNYERIHSRTMIMARGLQMVFPLMATWWLMASLANLALPPSINLMGELFITMSLFSWSNFTIILMGINIIITGMYSMYMIITTQRGKLTNHMINLQPSHTRELTLMALHMIPLILLTTSPKLITGLTM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03905-1", "uniprot_id": "NU4M_HUMAN", "id": "P03905-1", "name": "NADH-ubiquinone oxidoreductase chain 4", "aln": "MLKLIVPTIMLLPLTWLSKKHMIWINTTTHSLIISIIPLLFFNQINNNLFSCS-PTFSSDPLTTPLLMLTTWLLPLTIMASQRHLSSEPLSRKKLYLSMLISLQISLIMTFTATELIMFYIFFETTLIPTLAIITRWGNQPERLNAGTYFLFYTLVGSLPLLIALIYTHNTLGSLNILLLTLTAQELSNSWANNLMWLAYTMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRLTLILNPLTKHMAYPFLVLSLWGMIMTSSICLRQTDLKSLIAYSSISHMALVVTAILIQTPWSFTGAVILMIAHGLTSSLLFCLANSNYERTHSRIMILSQGLQTLLPLMAFWWLLASLANLALPPTINLLGELSVLVTTFSWSNITLLLTGLNMLVTALYSLYMFTTTQWGSLTHHINNMKPSFTRENTLMFMHLSPILLLSLNPDIITGFSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY1-1", "uniprot_id": "NU4M_DANRE", "id": "Q9MIY1-1", "name": "NADH-ubiquinone oxidoreductase chain 4", "aln": "MLKVLIPTIMLFPTIWLSSSKWLWTTTTMNSFLIAFISLTWLKWTSDTGWNASNSYMAADPLSTPLLVLTCWLLPLMILASQNHINSEPVNRQRMYITLLASLQTFMIMAFGATKIIMFYIMFEATLIPTLIIITRWGNQAERLNAGTYFLFYTLAGSLPLLVALLLLQQSTGTLSMLVLQYSDPLLLNSWGHKIWWAGCLIAFLVKMPLYGMHLWLPKAHVEAPVAGSMILAAVLLKLGGYGMMRMMVMLDPLSKQLAYPFIILALWGVIMTGLVCLRQTDLKSLIAYSSVGHMGLVAGGILIQTPWGFTGAIILMIAHGLTSSALFCLANTSYERTHSRTMILARGLQMVLPLATVWWFIANLANLALPPLPNLMGELMIITALFNWSPWTIIITGMGTLITANYSLYMFLTSQRGSIPEHITNLSPSHTREHLLMTLHLIPIILLMLKPELMWGWCN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18931-1", "uniprot_id": "NU4M_DROME", "id": "P18931-1", "name": "NADH-ubiquinone oxidoreductase chain 4", "aln": "MLKIIFFLLFLIPFCFINN---MYWMVQIMMFFISFIFLLMNNFMN--YWSEISYFLGCDMLSYGLILLSLWICSLMLLASE--MINKHNNYKNLFLLNIIILLLLLILTFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYLMNKIGSMNFYLMNN------FMFNYDLLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGMLRVISFLQLMNLKYSFVWISISLVGGVLVSLVCLRQTDLKALIAYSSVAHMGIVLSGLLTMTYWGLCGSYTLMIAHGLCSSGLFCLANVSYERLGSRSMLINKGLLNFMPSMTLWWFLLSSANMAAPPTLNLLGEIYLLNSIVSWSWISMILLSFLSFFSAAYTLYLYSFSQHGKLFSGVYSFSSGKIREYLLMLLHWLPLNLLILKSESFMLWL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::. ::*:* ::. : . ::::: * . . :..* *: *::*: *: .* ::**: : .. :.::: : * :*::* : .:::**::**::***** :* ** *.***:** *:***** *:*:*:.:: : *::.: :: : : : **::***:: :************::***:**.::****.***:*: :*: :. :: :: ::* * ::.. :********:******:.**.:* .:: * *.: *: ******* ** ****** .*** ** *:: :** .:* : **:: . **:* ** **:**: : : ..** :::: . ..:. *::*: :* *.: : .:... ** ** :* *: ** ... : ", "identical_positions": 147, "similar_positions": 155, "identity": "31.96%" }, { "cls_id": "homologset.agr.RGD:62056", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53670-1", "uniprot_id": "LIMK2_RAT", "id": "P53670-1", "name": "LIM domain kinase 2", "aln": "---------------------MAALAGEEAWRCRGCGNYVPLS--QRLYRTANEAWHSSCFRCSECQESLTNWYYEKDGKLYCHKDYWAKFGEFCHGCSLLMTGPAMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTESVQDQLPYSVTLISMP-ATTECRRGFSVSVESASSN------------YATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRVEEVEDAINQTSQTLQLLIEHDPVPQRLDQLRLDTRLSPHMQSSGHTLMLSTLDAKENQEGTLRR--------RSLRRSNSISKSPGPSSPKEPLLLSR----------------------------DISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRN-VDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERK------------RPPVEKAATKKRTLRKS---DRKKRYTVVGNPYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCKLEPESRPAFSKLEDSFEALSLFLGELAIPLPAELEELD----HTVSMEYGLTRDSPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54785-1", "uniprot_id": "LIMK2_MOUSE", "id": "O54785-1", "name": "LIM domain kinase 2", "aln": "---------------------MAALAGDEAWRCRGCGTYVPLS--QRLYRTANEAWHGSCFRCSECQESLTNWYYEKDGKLYCHKDYWAKFGEFCHGCSLLMTGPAMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTESVQDQLPYSVTLISMP-ATTECRRGFSVTVESASSN------------YATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRVEEVEDAIKQTSQTLQLLIEHDPVPQRLDQLRLDARLPPHMQSTGHTLMLSTLDTKENQEGTLRR--------RSLRRSNSISKSPGPSSPKEPLLLSR----------------------------DISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRS-VDPFPWQQKVRFAKGISSGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERK------------RPPVEKATTKKRTLRKS---DRKKRYTVVGNPYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCKLEPESRPAFSKLEDSFEALSLFLGELAIPLPAELEDLD----HTVSMEYGLTRDSPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53671-1", "uniprot_id": "LIMK2_HUMAN", "id": "P53671-1", "name": "LIM domain kinase 2", "aln": "---------------------MSALAGEDVWRCPGCGDHIAPS--QIWYRTVNETWHGSCFRCSECQDSLTNWYYEKDGKLYCPKDYWGKFGEFCHGCSLLMTGPFMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTESVQEQLPYSVTLISMP-ATTEGRRGFSVSVESACSN------------YATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRVEEVEDAISQTSQTLQLLIEHDPVSQRLDQLRLEARLAPHMQNAGHPHALSTLDTKENLEGTLRR--------RSLRRSNSISKSPGPSSPKEPLLFSR----------------------------DISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRS-MDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERK------------RAPMEKATTKKRTLRKN---DRKKRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESRPAFSKLEDSFEALSLYLGELGIPLPAELEELD----HTVSMQYGLTRDSPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IR79-1", "uniprot_id": "LIMK1_DROME", "id": "Q8IR79-1", "name": "LIM domain kinase 1", "aln": "MHHQQRLRANGGRGGTGLGAGSGPVSGGHSPLCAHCRGQLLPHPEEPIVMALGQQWHCDCFRCSVCEGHLHNWYFEREGLLYCREDYYGRFGDACQQCMAVITGPVMVAGEHKFHPECFCCTACGSFIGEGESYALVERSKLYCGQCYGKRSCQPADAKARITTAGKPM-HSIRLVEIPKDATPGLRVDGVALDDGCPTVRITDLFCNFFLWLTSMAEQCCGAPYRIDVNLTNLHIGDRILEVNGTPVSDSSVEQIDKLIRSNEKMLQLTVEHDPVQVCRSCSQADIQRAMSASTLILPLSTSASSVEVGRERLYKTPGEQGTKARKLRQATNASTTIPPAAGATAMTQLKEKERCSSLSKLLDEQHQAQQHSAHPQLYDLSRTQSCRVVQ-KPQRIFRATDLVIGEKLGEGFFGKVFKVTHRQSGEVMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKELIHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEIIGRVEADPDFMPRNSDFSLNQQEFREKFC-AQCPEPFVKVAFVCCDLNPDMRPCFETLHVWLQRLADDLAADRVPPERLLHEIETFQEWYASSEDALSPTSQRSLNNLDELVKSAVDSEISPVEKEKENMVIKPQDIPKSPHLGKDFSPSGERLRDSMRARRRQRFLGAQEERRNLTPDTESKERALKKALKKCRPFGERGYLVDLRAGAELQLEDVRDLNTYSDVDSSCDTSLNYHDVNNLPAAQEDENTVKPGKEELLEESTNKPSNQESQHHRLAIDDMRTRLNQCRSKFEHLEEASRRNFNQSQHSMKNFFKTPPVALKMFQRLEHEAAALNGGNNCPPPPPRTQRINQTPIFGRKNPPVAIVGQKLQHAESLEDLASSGVAKQLATPAPKRSKATATTKGGQSSNPPLFLPPSLNISVALNSNGNVTTTTNTNSSCPPSASDWLPKKHKLTLPLPSAQQQRTSSNHRLPMCNNKGKTLKPLPSRTGSQGIPASNCVSPTRSSRPGSPTKHLAQRHTAATAQRLTNAAATHQQQHQQQSSKTTRLNILSPEKVHRLGARLTDQKQKMREEAAATASSVGGAGCAAGTAAGSLNGHRTIGSSGTPNSAVGERRRRAAPSPPVRTHFNTRC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..::* . * * : : : .: ** .***** *: * ***:*::* *** :**:.:**: *: * ::*** *****.*:*****.* :* :* :*::****:::.****:*:.: * : :. . : :*: *:.:* :* * .*:::..... : *:: : . : * . :* ******:***** **:::. * ...: *** :***** . : : : . .. . *: ..: . * : *.**::.. *.: *:: .: : *:**::* * . .*:***. **: ** **:****:.:****: :*:***:*** *.***:*:.*:.** *:* *** :**************:::***: ** **::::. : :** *:**:*:.*:.**:***** ******** ***:: *::*:******:* : * . : . : . ***:. :*::***************::* .***.**:*****:******:* **** :**. **.** : * *** ::** .*. :* :** *:*: **.*..*. :: *: *. :* *.::: .* : .*: * ", "identical_positions": 261, "similar_positions": 198, "identity": "20.71%" }, { "cls_id": "homologset.agr.RGD:620560", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11661-1", "uniprot_id": "NU5M_RAT", "id": "P11661-1", "name": "NADH-ubiquinone oxidoreductase chain 5", "aln": "MN--MMTSSILMILILLTTPIIISMTNLPKLIDFPSYATSSIKFSFLLSLLPLLLFFHHNTEYMITNWHWLTINSIKLTMSFKIDYFSILFLSVALFVTWSIMQFSSWYMHSDPHINRFIKYLMMFLITMLILTSANNLFQLFIGWEGVGIMSFLLIGWWYGRADANTAALQAILYNRVGDIGFILAMTWFCLNMNSWELQQIFLT-NTN-NLVPLTGLLIAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLMIRFHPLTSNNSTIMTAMLCLGAITTLFTAICALTQNDIKKIVAFSTSSQLGLMMVTLGINQPYLAFLHICTHAFFKAMLFMCSGSIIHSLNDEQDIRKMGNMMKAMPFTSSCLIIGSLALTGMPFLTGFYSKDLIIEAINTCNTNAWALMITLIATSMTAVYSMRIIYFVTMTKPRYSPLITINENNPNLINPIKRLALGSILAGFLISLNIPPTNIQILTMPWHLKMTALLITILGFAIALELNN-LTLNLSMS-KPTKLSSFSTSLGYYPPIMHRIIPQKTLNSSYKLSLNLLDLIWLEKTIPKSTSITQTQLSKMMSNQ-KGLIKLYFLSFLITISLIFILHTLNPEWFQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03921-1", "uniprot_id": "NU5M_MOUSE", "id": "P03921-1", "name": "NADH-ubiquinone oxidoreductase chain 5", "aln": "MN--IFTTSILLIFILLLSPILISMSNLIKHINFPLYTTTSIKFSFIISLLPLLMFFHNNMEYMITTWHWVTMNSMELKMSFKTDFFSILFTSVALFVTWSIMQFSSWYMHSDPNINRFIKYLTLFLITMLILTSANNMFQLFIGWEGVGIMSFLLIGWWYGRTDANTAALQAILYNRIGDIGFILAMVWFSLNMNSWELQQIMFS-NNNDNLIPLMGLLIAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLVRFHPLTTNNNFILTTMLCLGALTTLFTAICALTQNDIKKIIAFSTSSQLGLMMVTLGMNQPHLAFLHICTHAFFKAMLFMCSGSIIHSLADEQDIRKMGNITKIMPFTSSCLVIGSLALTGMPFLTGFYSKDLIIEAINTCNTNAWALLITLIATSMTAMYSMRIIYFVTMTKPRFPPLISINENDPDLMNPIKRLAFGSIFAGFVISYNIPPTSIPVLTMPWFLKTTALIISVLGFLIALELNN-LTMKLSMN-KANPYSSFSTLLGFFPSIIHRITPMKSLNLSLKTSLTLLDLIWLEKTIPKSTSTLHTNMTTLTTNQ-KGLIKLYFMSFLINIILIIILYSINLE---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03915-1", "uniprot_id": "NU5M_HUMAN", "id": "P03915-1", "name": "NADH-ubiquinone oxidoreductase chain 5", "aln": "MT--MHTTMTTLTLTSLIPPILTTLVNPNKKNSYPHYVKSIVASTFIISLFPTTMFMCLDQEVIISNWHWATTQTTQLSLSFKLDYFSMMFIPVALFVTWSIMEFSLWYMNSDPNINQFFKYLLIFLITMLILVTANNLFQLFIGWEGVGIMSFLLISWWYARADANTAAIQAILYNRIGDIGFILALAWFILHSNSWDPQQMALL-NANPSLTPLLGLLLAAAGKSAQLGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFHPLAENSPLIQTLTLCLGAITTLFAAVCALTQNDIKKIVAFSTSSQLGLMMVTIGINQPHLAFLHICTHAFFKAMLFMCSGSIIHNLNNEQDIRKMGGLLKTMPLTSTSLTIGSLALAGMPFLTGFYSKDHIIETANMSYTNAWALSITLIATSLTSAYSTRMILLTLTGQPRFPTLTNINENNPTLLNPIKRLAAGSLFAGFLITNNISPASPFQTTIPLYLKLTALAVTFLGLLTALDLNY-LTNKLKMK-SPLCTFYFSNMLGFYPSITHRTIPYLGLLTSQNLPLLLLDLTWLEKLLPKTISQHQISTSIITSTQ-KGMIKLYFLSFFFPLILTLLLIT-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9MIY0-1", "uniprot_id": "NU5M_DANRE", "id": "Q9MIY0-1", "name": "NADH-ubiquinone oxidoreductase chain 5", "aln": "MTDMIMPLTLILIFAVLSYPLLKPKSYSKSNNSFQAWN--AVHVSFLISLIPLTMMLYKESDHVVMCWSWMNTQAFNVDLSFKFDYYSVTFTSIALFITWSILEFASWYMASYPQKELFYKYLLLFLMSMIILVTANNLFQLFIGWEGVGIMSFLLIGWWFGRTEANTASLQAVIYNRMGDIGFILTLAWMAMYLNSWDIQQIFILSKDFDMTIPQIGLIIAATGKSAQFTLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRLHPIMETNKLAPTICLCLGALTTLFAATCALTQNDIKKIVAFSTSSQLGLMMVAIGLNQPHLAFFHICTHAFFKAMLFLCSGAIIHSLNNEQDIRKMGGTYHTLPMTTNYLTIGKMALMGTPFLAGFFSKDAILEAMTTSHLNAWALTLTLIATSFTAVYSFRMIYLVCLGSPRHKTYETIDEN-HIPTNTIQRLAWGSIIAGLIISYTMIPLKTPILTMPIYLKLAAILVTLLGIILGLEIST-LANKINKNTTPGIPFHFSISLIFFP-ILHRLIPMRKLFMG-ESAATKIEKSWSELFGPCGIAFTLMTVATFVKDHRMASIKSYLAVFLTSIILKMMMLKLYT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18932-1", "uniprot_id": "NU5M_DROME", "id": "P18932-1", "name": "NADH-ubiquinone oxidoreductase chain 5", "aln": "-------------MCSISFVNLISMS---------------------LSCFLLSLYFLLNDMIYFIEWELVSLNSMSIVMTFLFDWMSLLFMSFVLMISSLVIFYSKEYMMNDNHINRFIMLVLMFVLSMMLLIISPNLISILLGWDGLGLVSYCLVIYFQN-IKSYNAGMLTALSNRIGDVALLLSIAWMLNYGSWNYIFYLEIMQNEFEMLMIGSLVMLAAMTKSAQIPFSSWLPAAMAAPTPVSALVHSSTLVTAGVYLLIRFN-IILSTSWLGQLMLLLSGLTMFMAGLGANFEFDLKKIIALSTLSQLGLMMSILSMGFLKLAMFHLLTHALFKALLFMCAGAIIHNMNNSQDIRLMGGLSIHMPLTSACFNVSNLALCGMPFLAGFYSKDMILEIVSISNVNMFSFFLYYFSTGLTVSYSFRLVYYSMTGDLNCGSLNMLNDESWIMLRGMMGLLIMSIIGGSMLNWLIFPFP-YMICLPIYMKLLTLFVCIVGGLFGYLISLSNLFFLNKSLFMYNLSTFLGSMWFMPYISTYGMIFYPLNYG-QLVVKSFDQGWSEYFGGQHLYQKLSMYSKTLFLMHNNSLKIYLLLFVFWILILLILLFL------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . :* : : : : . * . :: .: ::* *: *: * ...*::: :: :: ** . : : * : :*:::*::* : *::.:::**:*:*::*: *: :: .: .*.: : : **:**:.::*::.*: . : : : :::** ****: : .***:** .*******:****:*.**::*::*:: : .. * *..:* :::. * : *:***:*:** ******* :.:. **::*: ***:***:**:*:*:***.: :.**** **. :*:*: : :..:** * ***:**:*** *:* . . * ::: : ::*.:* ** *:: . . . :::: . : * *::.* ::. : * :* .:* :: : .:* . :. :. . * : : * * * . : :: * * : :* *: *. : : ::: ", "identical_positions": 131, "similar_positions": 190, "identity": "21.27%" }, { "cls_id": "homologset.agr.RGD:620561", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P03926-1", "uniprot_id": "NU6M_RAT", "id": "P03926-1", "name": "NADH-ubiquinone oxidoreductase chain 6", "aln": "MTNYMFILSLLFLTGCLGLALKPSPIYGGLGLIVSGCIGCLMVLGFGGSFLG-LMVFLIYLGGMLVVFGYTTAMATEEYPETWGSNWFIFSFFVLGLFMEL-VVFYLFSLNNKVELVDFDSLGDWLMYEIDDVGVMLEGGIGVAAIYSCAT-WMMVVAGWSLFAGIFIIIEITRD---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03925-1", "uniprot_id": "NU6M_MOUSE", "id": "P03925-1", "name": "NADH-ubiquinone oxidoreductase chain 6", "aln": "MNNYIFVLSSLFLVGCLGLALKPSPIYGGLGLIVSGFVGCLMVLGFGGSFLG-LMVFLIYLGGMLVVFGYTTAMATEEYPETWGSNWLILGFLVLGVIMEV-FLICVLNYYDEVGVINLDGLGDWLMYEVDDVGVMLEGGIGVAAMYSCAT-WMMVVAGWSLFAGIFIIIEITRD---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03923-1", "uniprot_id": "NU6M_HUMAN", "id": "P03923-1", "name": "NADH-ubiquinone oxidoreductase chain 6", "aln": "MMYALFLLSVGLVMGFVGFSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMG-LMVFLIYLGGMMVVFGYTTAMAIEEYPEAWGSGVEVLVSVLVGLAMEVGLVLWVKEYDGVVVVVNFNSVGSWMIYEGEGSGLIREDPIGAGALYDYGR-WLVVVTGWTLFVGVYIVIEIARGN--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18933-1", "uniprot_id": "NU6M_DROME", "id": "P18933-1", "name": "NADH-ubiquinone oxidoreductase chain 6", "aln": "--MIQLMLYSLIITTSIIFLNMIHPLALGLTLLIQTIFVCLLTGLMTKSFWYSYILFLIFLGGMLVLFIYVTSLASNEMFN-LSMKLTLFSSLILIFMLILSFIMDKTSSSLFLMNNDMQSIINMNSY-------FMENSLSLNKLYNFPTNFITILLMNYLLITLIVIVKITKLFKGPIRMMS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* :: : : *: ** *::. . *:: : .: ::***:****:*:* *.*::* :* : . :: .:: . : : .:: . : :::.: . * : *. :. :*. :: :: *: : ::::*:: ", "identical_positions": 24, "similar_positions": 64, "identity": "13.04%" }, { "cls_id": "homologset.agr.RGD:620562", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R103-1", "uniprot_id": "IL12A_RAT", "id": "Q9R103-1", "name": "Interleukin-12 subunit alpha", "aln": "--------MCQSRYLLFLATLVLLNHLTSARVIPVSGPAK----CLNQSQNLLKTTDDMVRTAREKLKHYSCTAGDIDHEDITRDKTSTLEACLPLELHKNESCLATKETSSIIRGSCLPPQKTSLMMTLCLGSIYEDLKMYQSEFQAINAALQSHNHQQITLDRNMLMAIDELMRSLNHSGETLHQKAPMGEADPYRVKMKLCILLHAFSTRVMTINRVMNYLSSS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43431-1", "uniprot_id": "IL12A_MOUSE", "id": "P43431-1", "name": "Interleukin-12 subunit alpha", "aln": "--------MCQSRYLLFLATLALLNHLSLARVIPVSGPAR----CLSQSRNLLKTTDDMVKTAREKLKHYSCTAEDIDHEDITRDQTSTLKTCLPLELHKNESCLATRETSSTTRGSCLPPQKTSLMMTLCLGSIYEDLKMYQTEFQAINAALQNHNHQQIILDKGMLVAIDELMQSLNHNGETLRQKPPVGEADPYRVKMKLCILLHAFSTRVVTINRVMGYLSSA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29459-1", "uniprot_id": "IL12A_HUMAN", "id": "P29459-1", "name": "Interleukin-12 subunit alpha", "aln": "--------MCPARSLLLVATLVLLDHLSLARNLPVATPDPGMFPCLHHSQNLLRAVSNMLQKARQTLEFYPCTSEEIDHEDITKDKTSTVEACLPLELTKNESCLNSRETSFITNGSCLASRKTSFMMALCLSSIYEDLKMYQVEFKTMNAKLLMDPKRQIFLDQNMLAVIDELMQALNFNSETVPQKSSLEEPDFYKTKIKLCILLHAFRIRAVTIDRVMSYLNAS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2C4-1", "uniprot_id": "A0A8M6Z2C4_DANRE", "id": "A0A8M6Z2C4-1", "name": "", "aln": "MCEFIRLYMCMCICVCVCVGIVISMALALALCSPVPPPDSQECVCSPAARSLLSALTHIMEKE----------GKMKEQDLFAGFNCTDLEAQMTPHTHTSSVCQP----SVSANSSCSAHRSSNFSAVECVKNIRGDLRYYDLLLNSYKPSTQELS-PVITANTQLINCLNQRCESA----EGVFPQWRVWKGSSFDDRVSLCKTLKGFHIRSITVNRALAYIASGEHRK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z3D3-1", "uniprot_id": "A0A8M6Z3D3_DANRE", "id": "A0A8M6Z3D3-1", "name": "Interleukin-12 subunit alpha", "aln": "MLSRFCYYFALSGIMCCLLWRCGIAGPVGGFKSPVLGLTG--KACNPLARSLLWNVSAVLEMD----------------HLFSGFDCAQQNAEVYLKTQTVSVCTP-------QNSNCAQSAIVNIDESECLQRILEDLHYYRETFLAYSKPELTTT-VVRGIEDVMQNCFSVSVTEN------SPAKASMDHQKSFQERLKLCKILKGFSLRAITINRVFNYILTK----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . : . ** * ::.** ::. . :: . : :: : . . . * ...* .: *: * **: * : : . : : :. : : . . : ::.** *:.* * :*::*.: *: : ", "identical_positions": 20, "similar_positions": 53, "identity": "8.66%" }, { "cls_id": "homologset.agr.RGD:620563", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61794-1", "uniprot_id": "LPAR1_RAT", "id": "P61794-1", "name": "Lysophosphatidic acid receptor 1", "aln": "MAAASTSSPVISQPQFTAMNEQQCFYNESIAFFYNRSGKYLATEWNTVSKLVMGLGITVCVFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIDHCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIVCWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRNENPNGPTEGSDRSASSLNHTILAGVHSNDHSVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61793-1", "uniprot_id": "LPAR1_MOUSE", "id": "P61793-1", "name": "Lysophosphatidic acid receptor 1", "aln": "MAAASTSSPVISQPQFTAMNEQQCFYNESIAFFYNRSGKYLATEWNTVSKLVMGLGITVCVFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIDHCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIVCWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRNENPNGPTEGSDRSASSLNHTILAGVHSNDHSVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92633-1", "uniprot_id": "LPAR1_HUMAN", "id": "Q92633-1", "name": "Lysophosphatidic acid receptor 1", "aln": "MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *** ************* *****************:********************:***********************************************************************************************************************************::**************************************************************************:*************************************************************.***.*****************************", "identical_positions": 354, "similar_positions": 7, "identity": "97.25%" }, { "cls_id": "homologset.agr.RGD:620565", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K5E0-1", "uniprot_id": "LPAR3_RAT", "id": "Q8K5E0-1", "name": "Lysophosphatidic acid receptor 3", "aln": "MNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWLLRQGLLDTSLTASLANLLVIAVERHMSIMRMRIHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVVVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCAPHDSNAERHPSRIPSTIHSRSDTGSQYLEDSISQGQVCNKSSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQ31-1", "uniprot_id": "LPAR3_MOUSE", "id": "Q9EQ31-1", "name": "Lysophosphatidic acid receptor 3", "aln": "MNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDTSLTASLANLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVAVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCALQDSNTERRPSRNPSTIHSRSETGSQYLEDSISQGPVCNKNGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBY5-1", "uniprot_id": "LPAR3_HUMAN", "id": "Q9UBY5-1", "name": "Lysophosphatidic acid receptor 3", "aln": "MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQE-NPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********:************.*:********************************.*********************************************:*******:******:*****************:****************************************************:*******:**:***.**:***:*********************:*********************************:**.*****************:*************.**:***** :: *.**:*** ***: ***:*****:******* ****. *", "identical_positions": 319, "similar_positions": 28, "identity": "90.11%" }, { "cls_id": "homologset.agr.RGD:620566", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKM5-1", "uniprot_id": "S1PR5_RAT", "id": "Q9JKM5-1", "name": "Sphingosine 1-phosphate receptor 5", "aln": "MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAAVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYATNILLSGPLTLRLSPALWFAREGGVFVALAASVLSLLAIALERHLTMARRGPAPAASRARTLAMAVAAWGLSLLLGLLPALGWNCLGRLEACSTVLPLYAKAYVLFCVLAFLGILAAICALYARIYCQVRANARRLRAGPGSRRATSSSRSRHTPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARACPVLLQADPFLGLAMANSLLNPIIYTFTNRDLRHALLRLLCCGRGPCNQDSSNSLQRSPSAVGPSGGGLRRCLPPTLDRSSSPSEHSCPQRDGMDTSCSTGSPGAATANRTLVPD-ATD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91X56-1", "uniprot_id": "S1PR5_MOUSE", "id": "Q91X56-1", "name": "Sphingosine 1-phosphate receptor 5", "aln": "MEPGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAAVCLAVCAFIVLENLAVLLVLVRHPRFHAPMFLLLGSLTLSDLLAGAAYATNILLSGPLTLRLSPALWFAREGGVFVALAASVLSLLAIALERHLTMARRGPAPAASRARTLAMAVAAWGASLLLGLLPALGWNCLGRLETCSTVLPLYAKAYVLFCVLAFLGILAAICALYARIYCQVRANARRLRAGPGSRRATSSSRSRHTPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARACPVLLQADPFLGLAMANSLLNPIIYTFTNRDLRHALLRLLCCGRGPCNQDSSNSLQRSPSAAGPSGGGLRRCLPPTLDRSSSPSEHLSPQQDGVDTSCSTGSPGVATANRSLVPT-ATD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H228-1", "uniprot_id": "S1PR5_HUMAN", "id": "Q9H228-1", "name": "Sphingosine 1-phosphate receptor 5", "aln": "MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGT-AGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQ-SASAAEASGG-LRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*************************************.******************** ****************************:**********:*****************:************* **********.:**.******.**** ******************::********************:************************ * **: .*:*:*:*:.*************************************:**************************:************:**** .*.:*.*.* * *.**. .*** ******* ** * * **: .**:**:*** ******..** *:**. *:*", "identical_positions": 341, "similar_positions": 39, "identity": "85.04%" }, { "cls_id": "homologset.agr.RGD:620569", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54708-1", "uniprot_id": "AT12A_RAT", "id": "P54708-1", "name": "Potassium-transporting ATPase alpha chain 2", "aln": "-MRRKT-EIYSVELNGTKDVKPAD--QRDDK-KFKGAKNKDLEPNKSHEKEELKKELDLDDHRLSNTELEQKYGTNIIQGLSSVRATELLARDGPNTLTPPKQTPEIIKFLKQMVGGFSILLWIGAALCWIAFVIQYVNN-SASLDNVYLGAILVLVVILTGIFAYYQEAKSTNIMASFSKMIPQQALVIRDAEKKVISAEQLVVGDVVEIKGGDQIPADIRLVFSQGCKVDNSSLTGESEPQARSTEFTHENPLETKNIGFYSTTCLEGTATGIVINTGDRTIIGRIASLASGVGSEKTPIAIEIEHFVHIVAGVAVSIDIIFFITAVCMKYYVLDAIIFLISIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSENQTKQAFDQSSGTWASLSKIITLCNRAEFRPGQESVPIMKRTVVGDASETALLKFSEVILGDVMGIRKRNHKVAEIPFNSTNKFQLSIHETEDPNNKRFLVVMKGAPERILEKCSTIMINGQEQPLDKSSADSFHTAYMELGGLGERVLGFCHLYLPAEQFPQSYIFDVDSVNFPTSNFCFVGLLSMIDPPRSTVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANNETVEDIAKRRNIAVEQVNKREAKAAVVTGMELKDMTPEQLDELLTNYQEIVFARTSPQQKLIIVEGCQRQDAIVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYTLTKNIAELCPFLIYIVAGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKKKDRLVNTQLAIYSYLHIGLMQALGGFLVYFTVYAQQGFWPTSLINLRVAWETDDINDLEDSYGQEWTRYQRKYLEWTGSTAFFVAIMIQQIADLIIRKTRRNSIFQQGLFRNKVIWVGIASQVIVALILSYGLGSVPALSFTMLRVQYWFVAVPHAILIWVYDEMRKLFIRLYPGSWWDKNMYY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1W8-1", "uniprot_id": "AT12A_MOUSE", "id": "Q9Z1W8-1", "name": "Potassium-transporting ATPase alpha chain 2", "aln": "-MRRKT-EIYSVELNGTKDVELAD--QKDDK-KFKGGKNKDSEPNKSQE-EELKKELDLDDHRLSNTDLEQKYGTNIIQGLSSIRAAELLARDGPNALTPPKQTPEIIKFLKQMVGGFSILLWIGAALCWIAYVIQYVSS-TASLDNVYLGAILVLVVILTGIFAYYQEAKSTNIMASFSKMIPQQALVIRDAEKKIIPAEQLVVGDVVEIKGGDQIPADIRLVFSQGCKVDNSSLTGESEPQARSTEFTHENPLETKNIGFYSTTCLEGTATGIVINTGDRTIIGRIASLASGVGSEKTPIAIEIEHFVHIVAAVAVSVGVIFFITAVCMKYYVLDAIIFLISIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSENQTKQAFDQSSGTWASLSKIITLCNRAEFRPGQESVPIMKRVVVGDASETALLKFSEVILGDVMDIRKRNHKVAEIPFNSTNKFQLSIHETEDPNDKRFLMVMKGAPERILEKCSTIMINGQEQPLDKSSADAFHTAYMELGGLGERVLGFCHLYLPADKFPQSYTFDVDSINFPTSNLCFVGLLSMIDPPRSTVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANNETVEDIAKRRNIAVEQVNKREAKAAVVTGMELKDMTPEQLDELLINYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYTLTKNIAELCPFLIYIVAGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKKKDRLVNKQLAIYSYLHIGLMQALGGFLVYFTVYAQQGFWPTSLINLRVSWETDDINDLEDSYGQEWTRYQRKYLEWTGSTAFFVAIMVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGIISQIIVALVLSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEMRKLFIRLYPGSWWDKNMYY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54707-1", "uniprot_id": "AT12A_HUMAN", "id": "P54707-1", "name": "Potassium-transporting ATPase alpha chain 2", "aln": "-MHQKTPEIYSVELSGTKDIVKTD--KGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13607-1", "uniprot_id": "ATNA_DROME", "id": "P13607-1", "name": "Sodium/potassium-transporting ATPase subunit alpha", "aln": "MALRSDYEHGRADSYRVATVIATDDDNRTADGQYKSRRKMPAKVNKKENLDDLKQELDIDFHKISPEELYQRFQTHPENGLSHAKAKENLERDGPNALTPPKQTPEWVKFCKNLFGGFAMLLWIGAILCFVAYSIQASTSEEPADDNLYLGIVLSAVVIVTGIFSYYQESKSSKIMESFKNMVPQFATVIREGEKLTLRAEDLVLGDVVEVKFGDRIPADIRIIEARNFKVDNSSLTGESEPQSRGAEFTHENPLETKNLAFFSTNAVEGTAKGVVISCGDHTVMGRIAGLASGLDTGETPIAKEIHHFIHLITGVAVFLGVTFFVIAFILGYHWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSGVQYDRTSPGFKALSRIATLCNRAEFKGGQDGVPILKKEVSGDASEAALLKCMELALGDVMNIRKRNKKIAEVPFNSTNKYQVSIHETEDTNDPRYLLVMKGAPERILERCSTIFINGKEKVLDEEMKEAFNNAYMELGGLGERVLGFCDFMLPSDKYPNGFKFNTDDINFPIDNLRFVGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEGNETVEDIAQRLNIPVSEVNPREAKAAVVHGAELRDVSSDQLDEILRYHTEIVFARTSPQQKLIIVEGCQRMGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLAFILCDIPLPLGTVTILCIDLGTDMVPAISLAYEHAEADIMKRPPRDPFNDKLVNSRLISMAYGQIGMIQAAAGFFVYFVIMAENGFLPKKLFGIRKMWDSKAVNDLTDSYGQEWTYRDRKTLEYTCHTAFFISIVVVQWADLIICKTRRNSIFQQG-MRNWALNFGLVFETVLAAFLSYCPGMEKGLRMYPLKLVWWFPAIPFALAIFIYDETRRFYLRRNPGGWLEQETYY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * .: . : :* : . :::. :: : :*... :::::**.:* *::* :* ::: *. *** :* * * *****:********* :** *::.***::***:** **::*: ** .. .: :*:*** :* ***:****:****:**::** **.:*:** * ***:.** : :*:**:**:**:* **:******:: ::. :*************.*.:************: *:**..:***..*:**. **:*::*:**.****:.. :**** **.**:*:::.*** :.: **: *. : * **::****.**************** *:*******.****************** ******************:******: ***:*::: :*::* : :**:* ********: **:.***:*: * *****:**** *: ***** *****:*:**:*******:*:**** :*.:. *:*:***********:****:***:*: **:. .:*:.****************.: **::::*: : *: * :*** .*: ****:*******::*****:******************************* ..*******:* **.*.:** *:****** * **:*::.:****:* : ********************* .*:********************:********.:*:****:*************************:***:**.**.*:.*** :*: .:***:**:*** ******::*:*:****:**:***:* **. :*:*** * :* :**::** ..*:***.: *::** * .*:.:* *:.. :*** ******** :*: **:* ****:.*:: * ***** *********** :** .: .*: : ::. .*** * .* : *: :** *:*.*: *::*** *::::* **.* ::: **", "identical_positions": 614, "similar_positions": 266, "identity": "58.93%" }, { "cls_id": "homologset.agr.RGD:62057", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AVC5-1", "uniprot_id": "A0A8I6AVC5_RAT", "id": "A0A8I6AVC5-1", "name": "Latent-transforming growth factor beta-binding protein 3", "aln": "MPGPRGAARGLAPAMRQAGASGLLALLLLA---LLGPGGGAEGGPAGERGTGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAAGTGAGTGSSGPGLARTGAMSTGPLPPLVPEGESVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIEGPNAEGPASSQHLLPHPKPPHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECVMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSTEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPALEDTEEERGVTLDPPVSEERSVQQSHPTTTTSPARPYPELISRPSPPTFHRFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGQCVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKTSRPPVCEDIDECRDPSTCPDGKCENKPGSFKCIACQPGYRSQGGGACRDINECSEGSPCSPGWCENLPGSYRCTCAQGYEPALDGLSCIDMDECETGNICHDGICTNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCVCDEGFTLTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMGEARGISAGSRAQEEMDMDECQDPAACRPGRCVNLPGSYRCECHPPWVPGSSGRDCQLPESQAEHGPERREVCWGQRGEDGMCMGPLAGPALTFDDCCCRQGRGWGTQCRPCPPRGTGSQCPTSQSESNSFWDTSPLLLGKSPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFTRSRPHGACVPQRRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61810-1", "uniprot_id": "LTBP3_MOUSE", "id": "Q61810-1", "name": "Latent-transforming growth factor beta-binding protein 3", "aln": "MPGPRGAAHGLAPAMRQAGALGLLALLLLA---LLGPGGGAEGGPAGERGTGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAAGTGAGTGSSGPGLARTGAMSTGPLPPLAPEGESVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIEGPNAEGPASSQHLLPHPKPQHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSTEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPLEDTEEERGVTMDPPVSEERSVQQSHPTTTTSPPRPYPELISRPSPPTFHRFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGQCVPGPSDYSCHCNAGYRSHPQHRYCVDVNECEAEPCGPGKGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECTKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPICEDIDECRDPSTCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECSEGTPCSPGWCENLPGSYRCTCAQGYEPAQDGLSCIDVDECEAGKVCQDGICTNTPGSFQCQCLSGYHLSRDRSRCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCVCDEGFTLTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEM---------------------------------------------------------------EHAPERREVCWGQRGEDGMCMGPLAGPALTFDDCCCRQGRGWGTQCRPCPPRGTGSQCPTSQSESNSFWDTSPLLLGKSPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFTRSRPHGACVPQRRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS15-1", "uniprot_id": "LTBP3_HUMAN", "id": "Q9NS15-1", "name": "Latent-transforming growth factor beta-binding protein 3", "aln": "MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMD----------------VDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRRR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******** **** ** *** ******** *** ** .*********:*********************************************************************************************.*:*.***.*****:****:***.****.***:*********************************************************************..***..*.********** *********************************************************************************************.***:**********************************************.*********************************:*****************************************************:**. ********** *.**************:**:*.**************:: ***********************************:*****.*******.*************************:***********************************:*****************************:****:***********:********************************:***:**:*************:******** ** ** **:*:****:*.:*.:***:*********************:***************************************************.********:*************** *************************************************************************************************:***:******************************************************************************* *:.****:***.******** **********************:*********:**:*********************.*********************************************************************************:**************", "identical_positions": 1175, "similar_positions": 62, "identity": "89.08%" }, { "cls_id": "homologset.agr.RGD:620570", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FHZ1-1", "uniprot_id": "F7FHZ1_RAT", "id": "F7FHZ1-1", "name": "Interferon gamma receptor 1", "aln": "MGPQAAVGRMILLVVLMLSAEIGSGALMSTEDPKPPSVPAPTNVLITSYDLNPVVHWKHQNVSQAAVFTVQVKMY---PDNWTDACTNIAHHYCNIYKHISYPDSSAWARVKAKVGQRESAYAQSEEFIMCRKGKVGPPGLDIGRK-EDQLIVHIFHPKVNVS---QETMFGDGNTCYTFDYTVFVKHYRSGEILHTEHSVLKEDCSETLCELNISVSTLNSNYCVSVVGKSSFWQVNTETSKDACIPFLHDDREESIWMLLVAPLLFLTIVVPALVCCYIKK-NPFKRKSIMLPKSLLSVVKNATSETKPESKYS-LVTSCQPAVLENETVICEEHLSTVTTP-----DSLEAPEQ-EELSKGTVATVAEGNTSPETTDSPPTPVQSGHFSLSSSNQS--GSCSLTTYHSRDGS-----------DSGLVGTGSSISDSDFLPNNDSETKMADPAPTPVRKALTFSGYDKPHVLVDVPVDGEGKESLIGYRLTGDTQELS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15261-1", "uniprot_id": "INGR1_MOUSE", "id": "P15261-1", "name": "Interferon gamma receptor 1", "aln": "MGPQAAAGRMILLVVLMLSAKVGSGALTSTEDPEPPSVPVPTNVLIKSYNLNPVVCWEYQNMSQTPIFTVQVKVY---SGSWTDSCTNISDHCCNIYEQIMYPDVSAWARVKAKVGQKESDYARSKEFLMCLKGKVGPPGLEIRRKKEEQLSVLVFHPEVVVNGESQGTMFGDGSTCYTFDYTVYVEHNRSGEILHTKHTVEKEECNETLCELNISVSTLDSRYCISVDGISSFWQVRTEKSKDVCIPPFHDDRKDSIWILVVAPLTVFTVVILVFAYWYTKK-NSFKRKSIMLPKSLLSVVKSATLETKPESKYS-LVTPHQPAVLESETVICEEPLSTVTAP-----DSPEAAEQ-EELSKETKALEAGGSTSAMTPDSPPTPTQRRSFSLLSSNQS--GPCSLTAYHSRNGS-----------DSGLVGSGSSISDLESLPNNNSETKMAEHDPPPVRKAPMASGYDKPHMLVDVLVDVGGKESLMGYRLTGEAQELS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15260-1", "uniprot_id": "INGR1_HUMAN", "id": "P15260-1", "name": "Interferon gamma receptor 1", "aln": "---------MALLFLLPLVMQGVSRAEMGTADLGPSSVPTPTNVTIESYNMNPIVYWEYQIMPQVPVFTVEVKNYGVKNSEWIDACINISHHYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFAVCRDGKIGPPKLDIRKE-EKQIMIDIFHPSVFVNGDEQEVDYDPETTCYIRVYNVYVRMNGS-EIQYKILTQKEDDCDEIQCQLAIPVSSLNSQYCVSAEGVLHVWGVTTEKSKEVCITIFNSSIKGSLWIPVVAALLLFLVLSLVFICFYIKKINPLKEKSIILPKSLISVVRSATLETKPESKYVSLITSYQPFSLEKE-VVCEEPLSPATVPGMHTEDNPGKVEHTEELSSITEVVTTEENIPDVVPGSHLTPIERESSSPLSSNQSEPGSIALNSYHSRNCSESDHSRNGFDTDSSCLESHSSLSDSEFPPNNKGEIKTEGQELITVIKAPTSFGYDKPHVLVDLLVDDSGKESLIGYRPTEDSKEFS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **.:* * : * * .* * *.***.**** * **::**:* *::* :.*..:***:** * ..* *:* **:.* *** .:: *. * *.****:***:** **:*:** :* .**:*** *:* :: *.*: : :***.* *. * . :. .*** *.*:*. * ** :. : :::*.* *:* *.**:*:*.**:*. * .* * **.**:.**. ::.. : *:*: :**.* .: :: .: * ** *.:*.***:*****:***:.** ******** *:*. ** **.* *:*** **..*.* *. *: ****. * . : . . ...* ** : * ***** *. :*.:****: * **. : : **:** : ***..* * .* ** ******:***: ** *****:*** * :::*:*", "identical_positions": 209, "similar_positions": 129, "identity": "41.72%" }, { "cls_id": "homologset.agr.RGD:620571", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63836-1", "uniprot_id": "SBP2_MOUSE", "id": "Q63836-1", "name": "Selenium-binding protein 2", "aln": "MATKCTKCGPGYPTPLEAMK-GPREEIVYLPCIYRNTGTEAPDYLATVDVDPKSPQYSQVIHRLPMPYLKDELHHSGWNTCSSCF--GDSTK---SRNKLILPGLISSRIYVVDVGSEPRAPKLHKVIEASEIQAKCNVSNTHTSHCLASGEVMVNTLGDLQGNGKGSFVLLDGETFEVKGTWEKPGGASPMGYDFWYQPRHNVMVSTEWAAPNVFKDGFNPAHVEAG-LYGSRIFVWDWQRHEIIQTLQMT-DGLIPLEIRFLHDPSATQGFVGCALSSNIQRFYKNEEGT-WSVEKVIQVPSKKVKG--WMLPEMPGLITDILLSLDDRFLYFSNWLHGDIRQYDISNPQKPRLTGQIFLGGSIVRGGS-VQVLEDQELTCQPEPLVVKGKRIPGGPQMIQLSLDGKRLYATTSLYSDWDKQFYPDLIREGSVMLQVDVDTVNGGLKLNPNFLVDFGKEPLGPALAHELRYPGGDCSSDIWI----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17563-1", "uniprot_id": "SBP1_MOUSE", "id": "P17563-1", "name": "Methanethiol oxidase", "aln": "MATKCTKCGPGYSTPLEAMK-GPREEIVYLPCIYRNTGTEAPDYLATVDVDPKSPQYSQVIHRLPMPYLKDELHHSGWNTCSSCF--GDSTK---SRNKLILPGLISSRIYVVDVGSEPRAPKLHKVIEASEIQAKCNVSSLHTSHCLASGEVMVSTLGDLQGNGKGSFVLLDGETFEVKGTWEKPGDAAPMGYDFWYQPRHNVMVSTEWAAPNVFKDGFNPAHVEAG-LYGSRIFVWDWQRHEIIQTLQMT-DGLIPLEIRFLHDPSATQGFVGCALSSNIQRFYKNAEGT-WSVEKVIQVPSKKVKG--WMLPEMPGLITDILLSLDDRFLYFSNWLHGDIRQYDISNPQKPRLAGQIFLGGSIVRGGS-VQVLEDQELTCQPEPLVVKGKRIPGGPQMIQLSLDGKRLYATTSLYSAWDKQFYPDLIREGSMMLQIDVDTVNGGLKLNPNFLVDFGKEPLGPALAHELRYPGGDCSSDIWI----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VIF7-1", "uniprot_id": "SBP1_RAT", "id": "Q8VIF7-1", "name": "Methanethiol oxidase", "aln": "MATKCTKCGPGYATPLEAMK-GPREEIVYLPCIYRNTGIEAPDYLATVDVDPKSPHYSQVIHRLPMPHLKDELHHSGWNTCSSCF--GDSTK---SRDKLILPSIISSRIYVVDVGSEPRAPKLHKVIEPNEIHAKCNLGNLHTSHCLASGEVMISSLGDPQGNGKGGFVLLDGETFEVKGTWEKPGGEAPMGYDFWYQPRHNIMVSTEWAAPNVFKDGFNPAHVEAG-LYGSHIHVWDWQRHEIIQTLQMK-DGLIPLEIRFLHDPDATQGFVGCALSSNIQRFYKNEGGT-WSVEKVIQVPSKKVKG--WMLPEMPGLITDILLSLDDRFLYFSNWLHGDIRQYDISNPKKPRLTGQIFLGGSIVKGGS-VQVLEDQELTCQPEPLVVKGKRVPGGPQMIQLSLDGKRLYVTTSLYSAWDKQFYPNLIREGSVMLQIDVDTANGGLKLNPNFLVDFGKEPLGPALAHELRYPGGDCSSDIWI----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13228-1", "uniprot_id": "SBP1_HUMAN", "id": "Q13228-1", "name": "Methanethiol oxidase", "aln": "MATKCGNCGPGYSTPLEAMK-GPREEIVYLPCIYRNTGTEAPDYLATVDVDPKSPQYCQVIHRLPMPNLKDELHHSGWNTCSSCF--GDSTK---SRTKLVLPSLISSRIYVVDVGSEPRAPKLHKVIEPKDIHAKCELAFLHTSHCLASGEVMISSLGDVKGNGKGGFVLLDGETFEVKGTWERPGGAAPLGYDFWYQPRHNVMISTEWAAPNVLRDGFNPADVEAG-LYGSHLYVWDWQRHEIVQTLSLK-DGLIPLEIRFLHNPDAAQGFVGCALSSTIQRFYKNEGGT-WSVEKVIQVPPKKVKG--WLLPEMPGLITDILLSLDDRFLYFSNWLHGDLRQYDISDPQRPRLTGQLFLGGSIVKGGP-VQVLEDEELKSQPEPLVVKGKRVAGGPQMIQLSLDGKRLYITTSLYSAWDKQFYPDLIREGSVMLQVDVDTVKGGLKLNPNFLVDFGKEPLGPALAHELRYPGGDCSSDIWI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PHD9-1", "uniprot_id": "SBP1_DANRE", "id": "Q6PHD9-1", "name": "Methanethiol oxidase", "aln": "MASTCSGCGPGYKTPLDAMK-GPREEIVYLPCIYRNTDIQKPDYLATVDINPQSPNFCKVIHRLPMPNLKDELHHSGWNACSSCF--DDPSK---RRNRLILPSLISSRIYVVDVGTDPRAPRLHKTVEPTDLFWKCGLANPHTSHCLGSGQIMISTMGDPSGNGKGGFVLLDGETFEVIGNWEQPGDAAPFGYDFWYQPRHNVMISTEWGAPKALGNGFNPADVKAG-HYGQRLHVWDWTTHKRIQTLDLGEEGAIPLEVRFLHDPAAAEGFVGCALQSTVFRFYKTPKGD-WAAEKVIKVPSKKVEG--WALPDMPGLITDILISLDDRFLYFSNWLHGDIRQYDITDRKNPRMVGQVFLGGSVLKDGP-VKVLEDKELDSQPTPRILKGK----------------RLYVTTSLYSAWDKQFYPDLIKEGSVMMQIDVNTDTGGLKLNENFLVDFGAEPEGPALAHELRYPGGDCTSDIWL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFZ4-1", "uniprot_id": "Q9VFZ4_DROME", "id": "Q9VFZ4-1", "name": "Methanethiol oxidase", "aln": "MSNKTCCRGPGYATPLDAMRSGPREKLLYTVTVQPNLDEPHGDYLSTVDVDPESPTYCQIVHRTFTNRKGDELHHSGWNACSSCYYVDESSKTVPKRDRLVLPSLNSDFIYILDVVTDPRKPEIVKTIDG-DVLKSHNVTAPHTTHCLANGNIMISVMGDAEGYAKGDFILFDSD-FNCIGTWTKGDKKALCGYDFWYQPYFDVMVSSEWGAPNKWRRGWKNVDLEDMSQYGCRLNFYKWSTQTLYQTIDLGSDGITPLEIRFLHNPKKAEGFVGCALNAKVFHFKKKSDSDEFEAKKVIDIPGKLVDTGSGVAEDMGGMISDIIISLDDRFLYVNCWRHGDVRQYDITDPENPKLTGQLFLGGAICSDLPNVIVKEDKELKERPPARYVKGRRLEGGPQMLQLSLDGKRLYVSSSLYSPWDKQFYPKMVSQGGHIVLIDVDTVNGGISLNEDFLVDFANEPYGPSLPHEMRYPGGDCTSDIWLANDA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.. **** ***:**: ****:::* : * . ***:***::*:** :.:::** *********:****: .:.:* * :*:**.: *. **::** ::** *.: *.:: :: . : **:***..*::*:. :** .* .**.*:*:*.: *: *.* : . : ******** .::*:*:**.**: *:: ..:: ** :: .:.* : **:.: :* ***:****:* ::*******.:.: :* *. . : .:***.:* * *. :* *:*:**::********.. * ***:*****:: :.*::.**:****:: . . * * **:** :* . :**: *** ::**** *******.:: :*. :: :**:* .**:.** :*****. ** **:*.**:*******:****: ", "identical_positions": 199, "similar_positions": 149, "identity": "40.78%" }, { "cls_id": "homologset.agr.RGD:620572", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R5H8-1", "uniprot_id": "FAIM1_RAT", "id": "Q8R5H8-1", "name": "Fas apoptotic inhibitory molecule 1", "aln": "MASGDDSPIFEDDESPLCSLEKMTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGKEEIRREWMFKLVGKETFFVGAAKTKATINIDAISGFAYEYTLEIDGKSLKKYMENRSKTTNTWVLHLDGEELRVVLEKDTMDVWCNGQRMETAGEFVDDGTETHFSVGNHDCYIKAVSSGKRREGIIHTLIVDNREIPELTQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUD8-1", "uniprot_id": "FAIM1_MOUSE", "id": "Q9WUD8-1", "name": "Fas apoptotic inhibitory molecule 1", "aln": "----------------------MTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGKEEIRREWMFKLVGKETFFVGAAKTKATINIDAISGFAYEYTLEIDGKSLKKYMENRSKTTSTWVLRLDGEDLRVVLEKDTMDVWCNGQKMETAGEFVDDGTETHFSVGNHGCYIKAVSSGKRKEGIIHTLIVDNREIPELTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVQ4-1", "uniprot_id": "FAIM1_HUMAN", "id": "Q9NVQ4-1", "name": "Fas apoptotic inhibitory molecule 1", "aln": "----------------------MTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGKEEIRKEWMFKLVGKETFYVGAAKTKATINIDAISGFAYEYTLEINGKSLKKYMEDRSKTTNTWVLHMDGENFRIVLEKDAMDVWCNGKKLETAGEFVDDGTETHFSIGNHDCYIKAVSSGKRKEGIIHTLIVDNREIPEIAS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****************************************:************:**************************:*********:*****.****::***::*:*****:*******:::****************:***.***********:****************::.", "identical_positions": 159, "similar_positions": 20, "identity": "79.1%" }, { "cls_id": "homologset.agr.RGD:620573", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61462-1", "uniprot_id": "CY24A_MOUSE", "id": "Q61462-1", "name": "Cytochrome b-245 light chain", "aln": "MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIAAGVLICLLEYPRGKRKKGSTMERCGQKYLTSVVKLFGPLTRNYYVRAALHFLLSVPAGFLLATILGTVCLAIASVIYLLAAIRGEQWTPIEPKPKERPQVGGTIKQPPTNPPPRPPAEVRKKPSEGEEEAASAG---GPQVNPMPVTDEVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62737-1", "uniprot_id": "CY24A_RAT", "id": "Q62737-1", "name": "Cytochrome b-245 light chain", "aln": "MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIVAGVLICLLEYPRGKRKKGSTMERCGQKYLTAVVKLFGPLTRNYYVRAVLHLLLSVPAGFLLATILGTVCLAIASVIYLLAAIRGEQWTPIEPKPKERPQVGGTIKQPPTNPPPRPPAEVRKKPSEAEEEAASAG---GPQVNPIPVTDEVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13498-1", "uniprot_id": "CY24A_HUMAN", "id": "P13498-1", "name": "Cytochrome b-245 light chain", "aln": "MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIVAGVFVCLLEYPRGKRKKGSTMERWGQKYMTAVVKLFGPFTRNYYVRAVLHLLLSVPAGFLLATILGTACLAIASGIYLLAAVRGEQWTPIEPKPRERPQIGGTIKQPPSNPPPRPPAEARKKPSEEEAAVAAGGPPGGPQVNPIPVTDEVV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************************************.***::****************** ****:*:*******:********.**:****************.****** ******:************:****:********:*********.****** * .*:.* ******:*******", "identical_positions": 169, "similar_positions": 18, "identity": "86.67%" }, { "cls_id": "homologset.agr.RGD:620574", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61093-1", "uniprot_id": "CY24B_MOUSE", "id": "Q61093-1", "name": "NADPH oxidase 2", "aln": "-------------MGNWAVNEGLSIFVILVWLGLNVFLFINYYKVYDDGPKYNYTRKLLGSALALARAPAAC--LNFNCMLILLPVCRNLLSFLRGSSACCSTRIRRQLDRNLTFHKMVAWMIALHTAIHTIAHLFN-----VEW--CVNARVGISDRYSIALSDIGDNENEEYLN-FAREKIKNPEGGLYVAVTRLAGIT-----GIVITLCLILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLAIHGAER-----------IVRGQTAESLEEHNLD--ICADKIEEWGKIKECPVPKFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQQ--KVVITKVVTHPFKTIELQMKKKGFKMEVGQYIFVKCPKVSKLEWH-----PFTLTSAPEEDFFS--------------IHIRIVGDWTEG-----------LFNACGCDK------------------------QEFQDAWKLPKIAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASILKSVWYKYCDN----------------------ATSLKLKKIYFYWLCRDTHAFEWFADLLQLL-ETQMQERNNANFLSYNIYLTGWDESQANHFAVHHDEE-------KDVITGLKQKTLYGRPNWDN-EFKTIASEHPN-TTIGVFLCG---------PEALAETLSKQS-----ISNSESGPRGVHFIFNKENF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ERL1-1", "uniprot_id": "Q9ERL1_RAT", "id": "Q9ERL1-1", "name": "NADPH oxidase 2", "aln": "-------------MGNWAVNEGLSIFVILVWLGLNVFLFVKYYKVYDDEPKYNYTRKLLGSALALARAPAAC--LNFNCMLILLPVCRNLLSFLRGSSACCSTRIRRQLDRNLTFHKMVAWMIALHTAIHTIAHLFN-----VEW--CVNARVGTSDPYSVALSNIGDKENEEYLN-FAREKIKNPEGGLYVAVTRLAGIT-----GIVITLCLILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLAIHGAER-----------IVRGQTSDSLKEHNLD--VCADKIKEWGKIKECPVPKFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQQ--KVVITKVVTHPFKTIELQMKKKGFKMEVGQYIFVKCPQVSKLEWH-----PFTLTSAPEEDFFS--------------IHIRIVGDWTEG-----------LFNACGCDK------------------------QEFQDAWKLPKIAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASILKSVWYKYCDN----------------------ATSLRLKKIYFYWLCRDTHAFEWFADLLQLL-ETQMQERNNANFLSYNIYLTGWDESQANHFAVHHDEE-------KDVITGLKQKTLYGRPNWDN-EFKTIASQHPN-TRIGVFLCG---------PEALAKTLSKQS-----ISNSESGPRGVHFIFNKENF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04839-1", "uniprot_id": "CY24B_HUMAN", "id": "P04839-1", "name": "NADPH oxidase 2", "aln": "-------------MGNWAVNEGLSIFVILVWLGLNVFLFVWYYRVYDIPPKFFYTRKLLGSALALARAPAAC--LNFNCMLILLPVCRNLLSFLRGSSACCSTRVRRQLDRNLTFHKMVAWMIALHSAIHTIAHLFN-----VEW--CVNARVNNSDPYSVALSELGDRQNESYLN-FARKRIKNPEGGLYLAVTLLAGIT-----GVVITLCLILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLAIHGAER-----------IVRGQTAESLAVHNIT--VCEQKISEWGKIKECPIPQFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQQ--KVVITKVVTHPFKTIELQMKKKGFKMEVGQYIFVKCPKVSKLEWH-----PFTLTSAPEEDFFS--------------IHIRIVGDWTEG-----------LFNACGCDK------------------------QEFQDAWKLPKIAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASILKSVWYKYCNN----------------------ATNLKLKKIYFYWLCRDTHAFEWFADLLQLL-ESQMQERNNAGFLSYNIYLTGWDESQANHFAVHHDEE-------KDVITGLKQKTLYGRPNWDN-EFKTIASQHPN-TRIGVFLCG---------PEALAETLSKQS-----ISNSESGPRGVHFIFNKENF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12209-1", "uniprot_id": "FRE8_YEAST", "id": "Q12209-1", "name": "Probable ferric reductase transmembrane component 8", "aln": "MNLKSIVSWFKEHLPSFDVDVDKHFRTLRVRKYSQICLLISFIIICVIIPLMNYL-LLTDKFFKICHHLKHH--VFNRRSWVHKTHMYHKQSLQLCLICFVFTSFFVIQGANGDLLEITKRMGRISVALMPPLLFLT-----LRP--SPLPHTLYLALLPLHKWISRIVVLESILHTWFYLYYMYINDTLYVKMRKLPNIY-----GVIALGLFLLIAITSVRYARRWSYRVFYYVHYVSTWLILVFLHYHARPGISYYTTLNVLILTGQIVYRLHITNVTR-VTIVPISSSLSLLEFPLTDLPKKPILPGGHLR--INIYHRNFLRRFFSHLIPFQHPFTIASIPSDNLVRLIIRNGHFPLRTNEKYYITGAFEPELSFISKPTVPFNITTKSSKNPFRNNSSALINSPLNFLIKAQRVFMCVGGSGISFGLPLLRILNFNGVNVRLLWVSRDYKDLEV---------LNHFKNNFEGMEIYISGTEGNEQDIEIDYIDYHDCAADINDEVRSISSSGRVSELGDNSMLSDGNPQPTEPNENTALLSKKSTLRNHHPPKTSDIPDINADDEIDFTYAFS-RSKSRKNTAQGTLTTHSSFNGSSVFRQPKIIEPPAQDPCLEAAPKKIRIPAGVKVFFGRPTLGDKDYEWCLQTECD-AETDSIQCCRWANQGRDHAEYLSQVWVLAAGPRGLIESTKRWATDGGLHFHGESFAL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53109-1", "uniprot_id": "AIM14_YEAST", "id": "P53109-1", "name": "Probable metalloreductase AIM14", "aln": "-------------------MKESPLITLVKRHSETHFANIKYGYYVLIISLVYLIGLALLRAFGRRTPSRSS--SAFKNKIIYRLYDIDPAIHLGILFFAVLIPFYYHYSLTTQSTVYLKRLGRLSYALIPLNLFLT-----LRPNWFLRKNCTYTDFIPFHKWFSRIITVIGLLHGIFFIIKWAIDDNVSLKQKLILKTFN--FAGFIISILVLFLLICSIGPMRRYNYRLFYIVHNLVNVAFILLTPIHSRPGVKFP----FLLLNCTLLFIHIINRIVFAKSLMILNKNANYSKTNLVHVRLPRAILPDYFEPGSHIRISPYRRINPLYWLLPSHPYTIASLAEDNSIDLIIKETSTAEPGSQIESLRSNPK-----------SFHLDQEKTYTLIN-------------SYPPSVPEECYSQG--------TNIAIICGGSG----------------------------ISFALPLFRHFFNKENVKYLKMIWLIKDYSEYELVLDYLKTNGLTFEKKLSNN---------------------KRISVFISGEYTAETRLDEITTNIDDENSEYE-MGSFNNEDEDLSISNFNSENADSNDNTPETSHSPTKE-------NGSMIEVKSKHSFTLSNELK-SFNNESAQVNQ-NETWLFSCG---------PPSLLQLS-------------KKYCNDERINFVCETYGL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08908-1", "uniprot_id": "FRE5_YEAST", "id": "Q08908-1", "name": "Ferric reductase transmembrane component 5", "aln": "-------MLFARLVLLLVYLAPGSLAKPASTKKRTQWDQIAIDACAKELESHKFDTDVKGRHATLCTYEPALGSWLHCAKDVLDSRKKSKKIFEKTFSKINQYCHDYHKDEVVSNEEYYRIFANASLFIRPLDEVKENIRYPVTPNKASLDRWVWAYFGPLDNIDKGNVYGVTICLYWIGVLFIAAVYHFLNFSRLKQTVFKNKVSAFLRGHYVLPALVHNHAMSVGRWFFIGLVPTRLETLVLFGYVLLHGFLLSSYNFDHNELLSDRRSQVLIFLSDRAGILAFAHFPLIVLFGGKNSTMTWLTGIRYTAFITYHKWLGRFMLVDCTIHAIGYTYHAYIENYWKYVKYSDLWTSGRHAMIIVGILVFFSFFFFRRHYYELFVITHIILAIGFFHACWKHCYKLGWGEWIMACALFWIADRILRLIKIAIFGMPWAKLKLCGESMIEVRISKSSKWWKAEPGQYIYLYFLRPKIFWQSHPFTVMDSLVEDGELVVVITVKNGLTKKLQEYLLESEGYTEMRVLAEGPYGQSTRTHLFESLLFIAGGAGVPGPLSMAIKAGRQVKSNDSHQMIKFVWSVRNLDLLEVYRKEIMVLKELNIDTKIYFTGERKDESNTEEGAIANMSTEGRLLTTSKSAEMITDFGRPNIDEIIEEAVSGAKSLLVTCCG--------SEGFVDKTRELT-------AKRVLEHGDKWIEYVEEFQNW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : : . . : . .. . ..: .: . : : : :: . : : : : : * . . : : * . : : . : :. . : : . : . :: . * . . . . . * . : . . . * : ", "identical_positions": 5, "similar_positions": 61, "identity": "0.7%" }, { "cls_id": "homologset.agr.RGD:620575", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPV5-1", "uniprot_id": "APAF_RAT", "id": "Q9EPV5-1", "name": "Apoptotic protease-activating factor 1", "aln": "--MDAKARNCLLQHKEALEKDIKTSYIMDHMISNG---VLTVVEEEKVKSQATQYQRAAALIKMILNKDNYAYISFYNALLHEGYKDLAGLLHSGLPLVSSSSGKDTDGGNTSFVRTVLCEGGVPQRPVIFVTRKKLVSAIQQKLWKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHALLEGCFSGGVHWVSIGKQDKS-GLLMKLQNLCTRLGQEES----FSQRLPLNIEEAKDRLR-VLMLRKHPRSLLILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVIP----VESGLGKEKGLEILSLFVNMKKEDLPVEAHSIIKECKGSPLVVSLVGALLRDFPNRWAYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCVLWDLETEEVEDILQEFVN--KSLLFCNRNGKSFCYYLHDLQVDFLTEKNRSQLQDLHRKMVTQFQRYHQPHTLSPGQEDCMYWYNFLAYHMASAGMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVCENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDTGRLYLEWINKKTIKNLSRLVVRPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGE--KLLDIKAHEDEVLCCAFSSDDSYIATCSVDKKVKIWDSGTGKLVHTYE-EHSEQVN-----------------------CCHFTNKSNHLLLATGSNDSFL---KLWDLNQKECRNTMFGHTNSVTHCRFSPDDELLASCSADGTLKLWDVRSAN----EKKSINVK------------------------------------RFFLSSEDPPEDVEVIVKCCSWSADGDRIIVAAKNKVLLLDIHTSG-LLTEIHTGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRVKVADCRGH----LSWVHG---------------------VMFSPDGSSFLTASDDQTIRVWETRK-------VCKNSAIVLKQEIDVVFQENEMMVLAVDNIRGLQLIAGKTGQIDYLPEAQVS---CCCLSPHLEYVAFGDEEGAIKIIELPNNRVFSSGIGHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTEEYVFLQAHQETVKDFRLLRDS---RLLSWSFDGTVKVWNVITG---RIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFE---LPSPLHELKGHNSCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQ----------------LLHLCAPISIEEGTATHGGWVTDVCFSPDRKMLVSAGGYLKWWN----VVTGESSQTFYTNGTNLKKIHVSPDFRTYVTVDNLGILYILQVLE-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88879-1", "uniprot_id": "APAF_MOUSE", "id": "O88879-1", "name": "Apoptotic protease-activating factor 1", "aln": "--MDAKARNCLLQHREALEKDIKTSYIMDHMISNG---VLSVIEEEKVKSQATQYQRAAALIKMILNKDNCAYISFYNALLHEGYKDLAALLQSGLPLVSSSSGKDTDGGITSFVRTVLCEGGVPQRPVIFVTRKKLVHAIQQKLWKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSLLEGCFSGGVHWVSIGKQDKS-GLLMKLQNLCMRLDQEES----FSQRLPLNIEEAKDRLR-VLMLRKHPRSLLILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKHVVP----VESGLGREKGLEILSLFVNMKKEDLPAEAHSIIKECKGSPLVVSLIGALLRDFPNRWAYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCVLWDLETEEVEDILQEFVN--KSLLFCNRNGKSFCYYLHDLQVDFLTEKNRSQLQDLHRKMVTQFQRYYQPHTLSPDQEDCMYWYNFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVAYRHILDEKDCAVCENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYRQAKLQAKQEGDTGRLYLEWINKKTIKNLSRLVVRPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGE--KLLDIKAHEDEVLCCAFSSDDSYIATCSADKKVKIWDSATGKLVHTYD-EHSEQVN-----------------------CCHFTNKSNHLLLATGSNDFFL---KLWDLNQKECRNTMFGHTNSVNHCRFSPDDELLASCSADGTLRLWDVRSAN----ERKSINVK------------------------------------RFFLSSEDPPEDVEVIVKCCSWSADGDKIIVAAKNKVLLFDIHTSG-LLAEIHTGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRLKVADCRGH----LSWVHG---------------------VMFSPDGSSFLTASDDQTIRVWETKK-------VCKNSAIVLKQEIDVVFQENETMVLAVDNIRGLQLIAGKTGQIDYLPEAQVS---CCCLSPHLEYVAFGDEDGAIKIIELPNNRVFSSGVGHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTGDYVFLQAHQETVKDFRLLQDS---RLLSWSFDGTVKVWNVITG---RIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFD---LLSPLHELKGHNGCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQ----------------LLHSCAPISVEEGTATHGGWVTDVCFSPDSKTLVSAGGYLKWWN----VATGDSSQTFYTNGTNLKKIHVSPDFRTYVTVDNLGILYILQVLE-------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14727-1", "uniprot_id": "APAF_HUMAN", "id": "O14727-1", "name": "Apoptotic protease-activating factor 1", "aln": "--MDAKARNCLLQHREALEKDIKTSYIMDHMISDG---FLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKS-GLLMKLQNLCTRLDQDES----FSQRLPLNIEEAKDRLR-ILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVP----VESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN--KSLLFCDRNGKSFRYYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGE--KLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYD-EHSEQVN-----------------------CCHFTNSSHHLLLATGSSDCFL---KLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSAN----ERKSINVK------------------------------------QFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSG-LLGEIHTGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGH----LSWVHG---------------------VMFSPDGSSFLTSSDDQTIRLWETKK-------VCKNSAVMLKQEVDVVFQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQVS---CCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNS---RLLSWSFDGTVKVWNIITG---NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD---LLLPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGE----------------LLHLCAPLS-EEGAATHGGWVTDLCFSPDGKMLISAGGYIKWWN----VVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9H8-1", "uniprot_id": "APAF_DANRE", "id": "Q9I9H8-1", "name": "Apoptotic protease-activating factor 1", "aln": "--MEERARSRLLRSKATLEQDIKASYLMDHMISDG---VLTNDEEAKVLSKATRKEQAVALLETLLRKDNRAYISFYNALIRESYGDLASLLHSDLPLLSPEGEKSFADGVSPSVQAILSVGGVPQRPVVFVSRPPLLNLIREMLYQLRDTPGWVTVFGMAGSGKSVMAAEVVRDRSLIKECFPDGVHWLSVGQCERA-DLLVRMQSLCFRLEQCQSS--DTSQRPPSTVEEAKERLR-FLMLRRFPRSLLILDDVWDSSSLRSFDIQCRVLLTTRNRALTDSVSGVRYEVP----VENGLDEEKALEILALYVNGKMHKLPEQARSIVSECKGSPLVVSLIGALLREFPDRWSYYLRQLQQKQFKRIRKSSSYDYEALDQAMDASLQVLEAEHQELYRDLSVMQKDIKVPAKVLSVLWGLELEEVEDVLQEFVN--KSLLFRDCNQRPYRYYLHDLQLDFLAEQNRDQIAELHKKMVRQYQRFYSKRPPDSADKDSLYWYQFIPYHMAKAGLSKELYSLMFSLDWVKEKARIMGSAHLINDYVEYGEILDKENSEVRVQFQEFLSLNGHHLEQRPFPDVVQLALSQPDRSEVYRQALMQAQKRASRGQIYLNWVNKNIEEGLSRLVMHPHQGAVYYACFSKDGSKIASCGASKALRVFKSTSGE--KLLELQAHEEDVLCCAFSPDDRHIATCASDRKVKLWNVERGVLIREFEVEHEEQIN-----------------------HCQFTNTGRRVLLATCSNDKFTN-TRLWNPNKKTSQNTMFGHMEPVNHCCFSPNDLYLATSSSDGSLKLFEVSSAN----EWKSIDVD------------------------------------SFFPESD---EEIKAMVKCSTWSADGSQIICAARNTVFVFDVETSD-LLLKLKTSRLSTIQFCHACPNSSLLAVALSHYTVELWNFESSKKKAECSGH----LSWVHC---------------------VQFSPDGSLLLSSSDDQTIRLWETDR-------VHTSSAVALKRDTDVLSSHSDATIIAPDSSNRLQVLSGSTGAVVLESEELSSRIRCSCISRNAAFVALGSEDGTVQVIEVPSSKASVKLSGHTKTVHHCQFTDDCEILITSSEDSTIRVWKWRTGECMVLQGHMEPVRKFHLLSSSSSPHLFSWSFDGTVKVWDLTRG---QMLQDLVCHEGAVLSCDVSSDGRLFATTSANRTAKVWSSA---SWKMLFLLEGHKDCVRSCRFSWDNKRLATGDDNGEIRLWSMLDGA----------------LLKICPRDTKDSMNSYHAGWVTDLHFSPDNRVLVSTAGYIKWWS----VESGEALQTFYTMGGNLKKIHVSPDFSTFITVDSIGILYILKRLEGEGT---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KLI1-1", "uniprot_id": "APAF_DROME", "id": "Q7KLI1-1", "name": "Apoptosome protein Dark", "aln": "MDFETGEHQYQYKDILSVFEDAFVDNFDCKDVQDMPKSILSKEEIDHIIMSKDAVSGTLRLFWTLLSKQEEMVQKFVEEVLRINYKFLMSPIKTEQRQPSMMTRMYIEQRDRLYNDNQVFAKYN-------VSRLQPYLKLRQALLELR-PAKNVLIDGVLGSGKTWVALDVCLS-YKVQCKMDFKIFWLNLKNCNSPETVLEMLQKLLYQIDPNWTSRSDHSSNIKLRIHSIQAELRRLLKSKPYENCLLVLLNVQNAKAWNAFNLSCKILLTTRFKQVTDFLSAATTTHISLDHHSMTLTPDEVKSLLLKYLDCRPQDLPREVLTTN------PRRLSIIAESIRDGLATWDNWKHVNCDKLTTIIESSLNVLEPAEYRKMFDRLSVFPPSAHIPTILLSLIWFDVIKSDVMVVVNKLHKYSLVEKQPKESTISIPSIYLELKVKLENEYALHRSIVDHYNIPKTFDSDDLIPPYLDQYFYSHIGHHLKNIEHP----ERMTLFRMVFLDFRFLEQKIRHDSTAWNASGSILNTLQQLKFYKPYICDNDPKYERLVNAILDFLPKIEENLICSKYTDLLRIALMAED-EAIFEEAHKQVQRFDDR-----VWFTNHGRFHQHRQIINLGDNEGRHAVYLHNDFCLIALASGQILLTDVSLEGEDTYLLRDESDSSDILRMAVFNQQKHLITLHCNGSVKLWSLWPDCPGRRHSGGSKQQLVNSVVKRFIGSYANLKIVAFYLNEDAGLPEANIQLHVAFINGDVSILNWDEQDQEFKLSHVPVLKTMQSGIRCFVQVLKRYYVVCTSNCTLTVWDLTNGSSNTLELHVFNVENDTPLALDVFDERSKTATVLLIFKYSVWRLNFLPGLSVSLQSEAVQLPEGSFITCGKRSTDGRYLLLGTSEGLIVYDLKISDPVLRSNVSEHIECVDIYELFDPVYKYIVLCGAKGKQVVHVHTLRSVSGSNSHQNREIAWVHSADEISVMTKACLEPNVYLRSLMDMTRERTQLLAVDSKERIHLIKPAISRISEWSTITPTHAASNCKINAISAFNDEQIFVGYVDGVIIDVIHDTALPQQFIEEPIDYLKQVSPNILVASAHSAQKTVIFQLEKIDPLQPNDQWPLMMDVSTKYASLQEGQYIILFSDHGVCHLDIANPSAFVKPKDSEEYIVGFDLKNSLLFLAYENNIIDVFRLIFSCNQLRYEQICEEEIAQKAKISYLVATDDGTMLAMGFENGTLELFAVENRKVQLIYSIEEVHEHCIRQLLFSPCKLLLIS--CAEQLCFWNVTHMRNNQLEREQKRRRSRRHKQHSVTQEDAVDAAPIAADIDVDVTFVADEFHPVNRGTAELWRNKRGNAIRPELLACVKFVGNEARQFFTDAHFSHFYAIDDEGVYYHLQLLELSRLQPPPDPVTLDIANQYEDLKNLRILDSPLMQDSDSEGADVVGNLVLEKNGGVARATPILEEASS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. : :: :* .. : : :.: .*: * :: . . : *: :* *:: .* : ::: .* * . :: * : *:* ::: * :*. . * : *: *.**: :* :. . :: : :.*:.: : : . :* :*.* :: : *.. :.. : .** .* : . ..**:* :* :. .:*: .*::***** : :** : . . * :: .:* ::: : .** :. : * :*::. :*: * : : :* . *..* . * . * :.:: . : **:: *: . :: : : . **. :* . *: : * ** :*. : : :* : *: : : . :. .: ::*. : : .. : . ::.. : :: : * * : : : :**. . * :.:::::.* : . ::.:* *.:: . *..:: * ::. . :* : .:. : : .:.: * . : ** ** ::...::* *. :: .: * : .**:*. . : .. .:*: . :.: . :: :* ..* : : * .: .:: :. :* .. . . .::: :* ::: ... * : ::*. . . : ::.* . *:** :: .: : ::: *:. *. :* . : : . :: . : . :: : .: . : . .* ::*** : :: : : :*: ...: *:: :. . . : : . :.: .: ::. : : *. * . . . ..: .:: :: : . .. : : : :* *:.. :: . : : * : * * . . :* ::. . .: .::. : : *. :: : * :::: . *: *:* ** * : :: :*.: . : . . . .. .*: * .* :. . * . . : . * : :::.....* : ::*. *: * *: ** ", "identical_positions": 140, "similar_positions": 442, "identity": "9.54%" }, { "cls_id": "homologset.agr.RGD:620576", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70500-1", "uniprot_id": "CDIPT_RAT", "id": "P70500-1", "name": "CDP-diacylglycerol--inositol 3-phosphatidyltransferase", "aln": "---------MPEENIFLFVPNLIGYARIVFAIISFYFMPCCPFTASSFYLLSGLLDAFDGHAARALNQGTRFGAMLDMLTDRCATMCLLVNLALLYPRATLLFQLSMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFNFSEGPLVGSVGLFRMGLWITAPIALLKSIISVIHLVTAARNMAALDAADRAKKK------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDP6-1", "uniprot_id": "CDIPT_MOUSE", "id": "Q8VDP6-1", "name": "CDP-diacylglycerol--inositol 3-phosphatidyltransferase", "aln": "---------MPEENIFLFVPNLIGYARIVFAIISFYFMPCCPFTASSFYLLSGLLDAFDGHAARALNQGTRFGAMLDMLTDRCATMCLLVNLALLYPRATLLFQLSMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFNFSEGPLVGSVGLFRMGLWVTAPIALLKSVISVIHLITAARNMAALDAADRAKKK------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14735-1", "uniprot_id": "CDIPT_HUMAN", "id": "O14735-1", "name": "CDP-diacylglycerol--inositol 3-phosphatidyltransferase", "aln": "---------MPDENIFLFVPNLIGYARIVFAIISFYFMPCCPLTASSFYLLSGLLDAFDGHAARALNQGTRFGAMLDMLTDRCSTMCLLVNLALLYPGATLFFQISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFHFSEGPLVGSVGLFRMGLWVTAPIALLKSLISVIHLITAARNMAALDAADRAKKK------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8SX37-1", "uniprot_id": "CDIPT_DROME", "id": "Q8SX37-1", "name": "CDP-diacylglycerol--inositol 3-phosphatidyltransferase", "aln": "MT------IAEHDNVFIFVPNLIGYARIVLALIAFWFMSTNYVISGWCYVTSALLDAVDGQAARAFNQSTRFGAMLDQLTDRCGTTGLLVTLAYFYPRYMFWFQLSIAIDVACHWLFMQTSVVVGRSSHKVND---NFIMRLYYQ-KDILTFMCCVNELFYVCLYLLHFTYGPLIFGASLFKILAFLTGPFAVLKALISVMHAYVAGIDLAAVDVRERQERRQKSEPVSGKKVE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06197-1", "uniprot_id": "PIS_YEAST", "id": "P06197-1", "name": "CDP-diacylglycerol--inositol 3-phosphatidyltransferase", "aln": "MSSNSTPEKVTAEHVLWYIPNKIGYVRVITAALSFFVMKNHPTAFTWLYSTSCLLDALDGTMARKYNQVSSLGAVLDMVTDRSSTAGLMCFLCVQYPQWCVFFQLMLGLDITSHYMHMYASLSAGKTSHKSVGEGESRLLHLYYTRRDVLFTICAFNELFYAGLYLQLFSN-----SATFGKWTTIISFPGYVFKQTANVVQLKRAALILADNDAKNANEKNKTY---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: ::** ***.*:: * ::*:.* * * ****.** ** ** : :**:** :***..* *: *. ** . **: :.:*::.*::.: :*: * *** . . ::::** : * :*. ***** *** *: .. : : :: * ::* .*:: *. :* *. : ::. ", "identical_positions": 61, "similar_positions": 64, "identity": "26.07%" }, { "cls_id": "homologset.agr.RGD:620577", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JI6-1", "uniprot_id": "RAP1B_MOUSE", "id": "Q99JI6-1", "name": "Ras-related protein Rap-1b", "aln": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------PGKAR-KKSSCQLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61224-1", "uniprot_id": "RAP1B_HUMAN", "id": "P61224-1", "name": "Ras-related protein Rap-1b", "aln": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------PGKAR-KKSSCQLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NIZ1-1", "uniprot_id": "RP1BL_HUMAN", "id": "A6NIZ1-1", "name": "Ras-related protein Rap-1b-like protein", "aln": "MREYKLVVLGSRGVGKSALTVQFVQGIFVEKYDPTIEDSYREQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------PGKAR-KKSSCQLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62636-1", "uniprot_id": "RAP1B_RAT", "id": "Q62636-1", "name": "Ras-related protein Rap-1b", "aln": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWSNCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------PGKAR-KKSSCQLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6TEN1-1", "uniprot_id": "RAP1B_DANRE", "id": "Q6TEN1-1", "name": "Ras-related protein Rap-1b", "aln": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNSCAFLESSAKSKINVNEIFYDLVRQINR-------------------------------------------------------------KTPV--------------------------TGKPR-KKSTCQLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08645-1", "uniprot_id": "RAP1_DROME", "id": "P08645-1", "name": "Ras-related protein Rap1", "aln": "MREYKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELGKNLATQFN-CAFMETSAKAKVNVNDIFYDLVRQINK-------------------------------------------------------------KSPE--------------------------KKQKKPKKSLCVLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13856-1", "uniprot_id": "RSR1_YEAST", "id": "P13856-1", "name": "Ras-related protein RSR1", "aln": "MRDYKLVVLGAGGVGKSCLTVQFVQGVYLDTYDPTIEDSYRKTIEIDNKVFDLEILDTAGIAQFTAMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLRIKDSDRVPMVLIGNKADLINERVISVEEGIEVSSKWGRVPFYETSALLRSNVDEVFVDLVRQIIRNEMESVAVKDARNQSQQFSKIESPSTRLPSSAKQDTKQSNNKQSSKGLYNKSSQGQAKVKQSTPVNEKHKPSHAVPKSGSSNRTGISATSQQKKKKKNASTCTIL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**:****: *****.******* ::::.**********: :*:* : ******** ******:**:*.* ** ****:* :.::::* :****:**:**:* ***:*:***.** :***:. * * ::: ::. .* *:** : **:::* ****** : .:* : : : * * :*", "identical_positions": 98, "similar_positions": 52, "identity": "36.03%" }, { "cls_id": "homologset.agr.RGD:620578", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35180-1", "uniprot_id": "SH3G3_RAT", "id": "O35180-1", "name": "Endophilin-A3", "aln": "MSVAGLKKQFHKASQLFSEKISGAEGTKLDEEFLDMEKKIDITSKAVAEILSKATEYLQPNPAYRAKLGMLNTMSKLRGQVKATGYPQTEGLLGDCMLKYGRELGED-SAFGNSLVEVGEALKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLRKLEGRRLDYDYKKKRVGKIPEEEIRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHRQSTEILQELQNKLELRIALASQVPRRDYMPK-------------------PVNTSSTNANGVEPSSSSKLTGTDIPS--DQPCCRGLYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLRGESGFFPINYVEVIVPLPR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62421-1", "uniprot_id": "SH3G3_MOUSE", "id": "Q62421-1", "name": "Endophilin-A3", "aln": "MSVAGLKKQFHKASQLFSEKISGAEGTKLDEEFLNMEKKIDITSKAVAEILSKATEYLQPNPAYRAKLGMLNTVSKLRGQVKATGYPQTEGLLGDCMLKYGKELGED-SAFGNSLVDVGEALKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLRKLEGRRLDYDYKKRRVGKIPEEEIRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHRQSTEILQELQSKLELRISLASKVPKREFMPK-------------------PVNMSSTDANGVGPSSSSKTPGTDTPA--DQPCCRGLYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLRGESGFFPINYVEVIVPLPP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99963-1", "uniprot_id": "SH3G3_HUMAN", "id": "Q99963-1", "name": "Endophilin-A3", "aln": "MSVAGLKKQFHKASQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILSKTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGED-STFGNALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEILQELQSKLQMRISAASSVPRREYKPR-------------------PVKRSSSELNGVSTTSVVKTTGSNIPM--DQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8T390-1", "uniprot_id": "SH3G3_DROME", "id": "Q8T390-1", "name": "Endophilin-A", "aln": "MAFAGLKKQINKANQYMTEKMGGAEGTKLDMDFMEMERKTDVTVELVEELQLKTKEFLQPNPTARAKMAAVKGISKLSGQAKSNTYPQPEGLLAECMLTYGKKLGEDNSVFAQALVEFGEALKQMADVKYSLDDNIKQNFLEPLHHMQTKDLKEVMHHRKKLQGRRLDFDCKRRRQAK--DDEIRGAEDKFGESLQLAQVGMFNLLENDTEHVSQLVTFAEALYDFHSQCADVLRGLQETLQEKRSEAESRPRNEFVPKTLLDLNLDGGGGGLNEDGTPSHISSSASPLPSPMRSPAKSMAVTPQRQQQPCCQALYDFEPENPGELAFKENDIITLLNRVDDNWFEGAVNGRTGYFPQSYVQVQVPLPNGN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.******::**.* ::**:.******** :*::**:* *:* : * *: *:.*:*****: ***:. :: :**: **.*:. ***.****.:***.**::**** *.*.::*::.**::* **:** *** *:**.*::**: :* *****: ** :**:*****:* *::* .* ::*:* * :** ** :**: .***:****.*:****..* ** *:* *.:::*: **..*: : : *.. *:.:: *: * : **: . . : * :****:.******** ***.***.***** *::*:**:** :.*.:*:** .**:* **** ", "identical_positions": 175, "similar_positions": 109, "identity": "47.17%" }, { "cls_id": "homologset.agr.RGD:620579", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88588-1", "uniprot_id": "PACS1_RAT", "id": "O88588-1", "name": "Phosphofurin acidic cluster sorting protein 1", "aln": "MAERGGAGGGPGGAGGGSSQRGSGVAQSPQQQPPQQPSQ--PQQPTPPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIILP-----------------------------------------ASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEE-EEESFSSEQEGSDDPLHGQDLFYEDEDLR----------------------------------------------------KVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPS---DSGPEMEETESILSTPKPKLKPFFEG-----------------------MSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKVKSTWIKNQDDSLTETDTLEITDQDMFGDASTS--------------------LVVPEKVKTPMKSSKADLQGSASPSKVEGTHTPRQKRS---TPLKERQLSKPLSERTNSSDSERSPDLGHSTQ--------------IPRKVVYDQLNQILVS-DAALPENVILVNTTDWQG-----QYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGSQSYLSSILRFFVKSLASKTPDWLGHMRFLIVPLG--SHPVAKYLGSVDSRYSSTFLDSAWRDLFSRSEP--------------------------PVSEPLDVVGRVMQYVNGATTTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSP-----------STAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYG-----------------------------DVIGLQVDYW-LGHPGERRREGDK------RDASSKNTLKSVFRSVQVSRLPHAGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDS-KSQVIEGISRLICSAKQ-QQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKPT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K212-1", "uniprot_id": "PACS1_MOUSE", "id": "Q8K212-1", "name": "Phosphofurin acidic cluster sorting protein 1", "aln": "MAERGGAGGGPGGSGGGSSQRGSGVAQSPQQQPQQQPPQ--PQQPTPPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIILP-----------------------------------------ASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEE-EEESFSSEQEGSDDPLHGQDLFYEDEDLR----------------------------------------------------KVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPS---DSGPEMEETESILSTPKPKLKPFFEG-----------------------MSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKVKSTWIKNQDDSLTETDTLEITDQDMFGDVSTS--------------------LVVPEKVKTPMKSSKADLQGSASPSKVEGTHTPRQKRS---TPLKERQLSKPLSERTNSSDSERSPDLGHSTQ--------------IPRKVVYDQLNQILVS-DAALPENVILVNTTDWQG-----QYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGSQSYLSSILRFFVKSLASKTPDWLGYMRFLIIPLG--SHPVAKYLGSVDSRYSSTFLDSAWRDLFSRSEP--------------------------PVSEPLDVVGRVMQYVNGATTTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSP-----------STAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYG-----------------------------DVIGLQVDYW-LGHPGERRREGDK------RDASSKNTLKSVFRSVQVSRLPHAGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDS-KSQVIEGISRLICSAKQ-QQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKTT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6VY07-1", "uniprot_id": "PACS1_HUMAN", "id": "Q6VY07-1", "name": "Phosphofurin acidic cluster sorting protein 1", "aln": "MAERGGAGGGPGGAGGGSGQRGSGVAQSPQQPPPQQQQQQPPQQPTPPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIVLP-----------------------------------------ASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEE-EEESFSSEQEGSDDPLHGQDLFYEDEDLR----------------------------------------------------KVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPS---DSGPEMEETESILSTPKPKLKPFFEG-----------------------MSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTLEITDQDMFGDASTS--------------------LVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRS---TPLKERQLSKPLSERTNSSDSERSPDLGHSTQ--------------IPRKVVYDQLNQILVS-DAALPENVILVNTTDWQG-----QYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSILRFFVKSLANKTSDWLGYMRFLIIPLG--SHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEP--------------------------PVSEQLDVAGRVMQYVNGAATTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSP-----------STAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYG-----------------------------DVIGLQVDYW-LGHPGERRREGDK------RDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDS-KSQVIEGISRLICSAKQ-QQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKAT-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCE7-1", "uniprot_id": "Q9VCE7_DROME", "id": "Q9VCE7-1", "name": "", "aln": "MKMVDKSSKLVDKFAVISGTGGSGPGGGPLN---------------------------LQSGGGGGGSGGGGGVSGSGGISGTAGLSAGAGMTTGQKPVPMKLFAAWEVDRTPPNCIPRLCSLTITRLSILTPLPGDTTSLSLAVKMQSSKRTLRSHEIPINGLALTSSASLQGNSPMSVAGGVGGGGVGTPGSVGTGGGLGVAVPLTETELDLHFSLQYPHFIKRDGNRLVILLQRRKKYKSRTILGYKTLAEGIIRMDAVLQKSMDMIIELTASGKNGRPGTVVACLRAERVSSIPVDHDNKNNNSVLLADRVAEYSDEDEEAEFSSGEFNDEANELGLIRGYDPKDPRDYNHPAKHDMRKYRNKLQRSGIEDCALVGHHPGSIQHHHPGVVVDSDSEFEMKDKSSSRAKFSRTISLQQRNFKQKIVALLKRFKVSEELEGESGHRGTAALRG-ERDLDALFQELESLSCCEGDDSGPDMDSIS-VGSTPKPSLRPFFTNSRIMLHDNITGNGGDLSQLVGGGLGPGTGTAGNSERRSSDKSDQLTNSSYNLENNKNQKCIHLTNNNNSATTPDRGGNDSSGNEGNAGYTDGQNSDPQNSPPRDKDYLRLQQMQQQQLTPVSSVAASMGSGSVITPAQTEKRSRLFRTSSNTPANAGSGGNSVSAISASGGGKRKHTLSLSAEPRSVLEACLSPTNVEPRKLLLDQLSRVFAGEDSAIPEVVTIISPPEALGGSALLAKLVTLFANSFKPAFVPQNTAEVKAVLQALMAKIQKYCNSNAKPPHTVKVLLIGGDWLQGATLRHYVELMGVRPPDWLNHLRFYLVPVGGSCGSVARHLSQMDQAYAVMFGSDNWTQLCERAAATAAAVSAVTTVNATALTTNLADAAGVAKSDIAELVQRIQRYLLAAGPCTQIPIAEAMVNYK----DEDSCQIFVPFVSDVRIGYLDAQASLDLEENAAGSNAVGSGLGSGSASSSAIPIGSQSSPNVHGVVSGSPPQQQSLGRISPPLQTPPSSASSHRERNTSESLSTPSSVQQQSFSGALAAAEAVELQVDYWPLVRPGEGHAKESKGGLSKGSDAGGKNSIKSTFRNLQVWRLPQHAQQLGDMFNGLTVSFATKEKKQKQIMRLGKKKDKERDLEKEQCVEGVARLICSPKQSHPVPLRVYIDGTEWTGVKFFQVSSQWQTHVKNFPIALIGCTPMSCAELS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . :. . . *. *** . .* : *......*... ..* : .::. :. ..*.* ** *:*:*:*****:...*:*** ***:.:* :*. : * .*: :***:*.*** ***:** : * *.****:* ********:***.*:* *:*****:**.********** *:*.* *:*:. : : * .: .. ** :: :** *:**:. :.: : : :**:* ** .*** : ..: * *: :* * * *.: * * : :* *:***:**********:*: * . :* *.*** *::.** . . ****:*:. . : *****.*:*** . :. .:. : .. .*... .: *.*. :* :: *. :.*:::* * .* ... *:.. : : :: **:.* :.: ..: : .: : .* *: ** : . .:.:* : *...:*. *. *:: ***:: ***.:::.. *:*:** * ::...: * :. *: :. **.. . .*.**:***.**:::**:***.*:. *:.*** :*.: .: **.:*: :. :..***.::** ::*:* . .**::*..:*. *: * .. * :* .*: . . *: ::. *: :*: .* . *:*:****:. : **** * *:**:. *::* :: .. .:.*.* .* .* :. . .. **..: .:.:**.. *:. . : :* *. . :.: ****** * :*** : : .* **..**::**.**.:** ***: .: . .:** *:** *: * ::** * *.* :**::*****.** : . *** ***.**:.:****:::** ****:**:.*:. : : ", "identical_positions": 322, "similar_positions": 346, "identity": "26.66%" }, { "cls_id": "homologset.agr.RGD:62058", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08590-1", "uniprot_id": "AOC3_RAT", "id": "O08590-1", "name": "Amine oxidase [copper-containing] 3", "aln": "MTQKTTLVLLALAVITIFALVCVLLAGRSGDGGRLSQPLHCPSVLPSVQPQTHPGQSQPFADLSPEELTAVMSFLIKHLGPGLVDAAQARPSDNCVFSVELQLPAKAAALAHLDRGGPPPVREALAIIFFGGQPKPNVSELVVGPLPHPSYMRDVTVERHG-GPLPYYRRPVLTREYQDIQEMIFHRELPQASGLLHHCCFYKRQGHNLLKMTTAPRGLQSGDRATWFGIYYNLSGAGFYPHPIGLELLVDHKALDPALWTIQKVFYQGRYYESLTQLEDMFEAGLVNVVLVPDNGTGGSWSLKSSVPPGRAPPLQFHPEGPRFSVQGSQVRSSLWAFSFGLGAFSGPRIFDIRFQGERVAYEISVQEAIALYGGNSPASMSTCYMDGSFGIGKYSTPLTRGVDCPYLATYVDWHFLLESQTPKTLRDAFCVFEQNQGLPLRRHHSDFYSHYFGGVVETVLVVRSVATLLNYDYVWDMVFHSNGAIEVKFHATGYITSAFFFGAGEKFGNRVAEHTLGTVHTHNAHFKVDLDVAGLKNWAWAEDLAFVPMNVPWQPEFQMQRLQVTRKLLETEEEAAFPLGNATPRYLYLASNHSNKWGHRRGYRIQILSFAGKPLPQESPIEKAFTWGRYHLAVTQRKEEEPSSSSIYNQNDPWTPTVDFTDFIS-NETIAGEDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSPDSIYFRKDQDVTDCEVNSLACLSQTANCVPDLPAFSHGGFTYK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70423-1", "uniprot_id": "AOC3_MOUSE", "id": "O70423-1", "name": "Amine oxidase [copper-containing] 3", "aln": "MTQKTTLVLLALAVITIFALVCVLLAGRSGDGGGLSQPLHCPSVLPSVQPRTHPSQSQPFADLSPEELTAVMSFLTKHLGPGLVDAAQARPSDNCVFSVELQLPAKAAALAHLDRGGPPPVREALAIIFFGGQPKPNVSELVVGPLPHPSYMRDVTVERHG-GPLPYYRRPVLDREYQDIEEMIFHRELPQASGLLHHCCFYKHQGQNLLTMTTAPRGLQSGDRATWFGLYYNLSGAGFYPHPIGLELLIDHKALDPALWTIQKVFYQGRYYESLTQLEDQFEAGLVNVVLVPNNGTGGSWSLKSSVPPGPAPPLQFHPQGPRFSVQGSQVSSSLWAFSFGLGAFSGPRIFDIRFQGERVAYEISVQEAIALYGGNSPASMSTCYVDGSFGIGKYSTPLIRGVDCPYLATYVDWHFLLESQAPKTLRDAFCVFEQNQGLPLRRHHSDFYSHYFGGVVGTVLVVRSVSTLLNYDYIWDMVFHPNGAIEVKFHATGYISSAFFFGAGEKFGNRVGAHTLGTVHTHSAHFKVDLDVAGLKNWAWAEDMAFVPTIVPWQPEYQMQRLQVTRKLLETEEEAAFPLGGATPRYLYLASNHSNKWGHRRGYRIQILSFAGKPLPQESPIEKAFTWGRYHLAVTQRKEEEPSSSSIFNQNDPWTPTVNFTDFIS-NETIAGEDLVAWVTAGFLHIPHAEDIPNTVTAGNSVGFFLRPYNFFDEDPSFHSADSIYFREGQDATACEVNPLACLSQTATCAPEIPAFSHGGFAYRDN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16853-1", "uniprot_id": "AOC3_HUMAN", "id": "Q16853-1", "name": "Amine oxidase [copper-containing] 3", "aln": "MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHG-GPLPYHRRPVLFQEYLDIDQMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFLHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSWSLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHPRGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDFSDFIN-NETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N4I9-1", "uniprot_id": "A0A8M1N4I9_DANRE", "id": "A0A8M1N4I9-1", "name": "Amine oxidase", "aln": "MDSLIKYIVILLALISVILNIVLICLNSNKPPKCMSQ-----SQASLNLQDTHSDRSLVFADLTPEEYKAVRDYMWAQKDLKISHSVLAKPSDNFLFLIDLSLPKKADVLRYLDKDGQKPAREASVVVFYG--EHRYLKEYVVS-LSGPLTHRDVTEQKYKTKTLPFTARTVTIGEYAQLFTLLYG-VFQKLETPLRESFGYNLQTNKLLPFEGMPRGIKAGDRKTWISFFRDFS--GMYIHPVGFEMLINHESSNSSDWTVDKLLYNGQYFNSIDAFIKRYQAGDLEKIVYKKIEN--FASLKPREKPTGLGPQQYYLQGKRFSVKNNQVVYLDWNFAFGMSSLTGMRAFDIRFEGQRIAYELSVQEAMSVYGSTTPGMILTKFLDSSIGIGRFAHELVRGIDCPYGATYVDTHRYIDTNVTQRFRNSICVFEHDIGRPLRRHFSDFFHNSYGGMANSALVIRSITAIGNYDYIWDFIFYQSGSVEARVHATGYISSSFLVDGNLKYGHQVAENVLGNIHTHFISFKVDLDILGEKNIFQTKDMVYEEVPLPWMPTEKAKIPRLVEQQVKTEKEAAMLHGAKTPRYLHIASKQTNRWGHNRSYRLQVLSFAGDPLPESESTEKSMSWARYKVAITKHKDEEQTSSSLYSQNYMWKPFVDFSKYIEDNETIDNEDLVAWVTAGFLHIPHAEDIPNTVTVGNGGGVLIRPHNYFNEDPSIHSPDGVHFIPGSEN-DCEYNKMACLEKDQ-CTSTLEPFTYHGFEGVMQFE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . ::: **:*::: : :: . . ** * . **..:* ****: ** .** :: : . : .:. *:**** :* ::*.** ** .* :**:.. *.*** .::*:* : :.* **. *. * **** ::: .**: *.* ** :: ::: : : . *:.. *: : .:*: : ***:::*** **:.:: ::* *:: * :*:*:*::*:: :.: **::*::*:*:*::*: : ::** :: :: . . ***. * * *:: :* ****:..:* * *:**:.:::* * **:**:*:*:.**:*:***:::**..:*. : * ::*..:*:*::: * **:**** ***** * ::::..: :*:::****:: * *****.**:: : :**:. :.**:**:::: ****:** :*: .*::* :.:*****:*:*:... *:*::*. :.**.:*** ******: * :* ::*:.: :** * : : ::..: :: *::**: * *****::**:::*:*** *.**:*:*****.***:... :.::* **::*:*::*:** :***::.** * * *:*:.:*. **** .:************************.**. *.::**:*:*:****::*.*.::* ..: ** * :*** : *.. : .*:: ** ", "identical_positions": 282, "similar_positions": 278, "identity": "36.67%" }, { "cls_id": "homologset.agr.RGD:620580", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13491-1", "uniprot_id": "GPM6B_HUMAN", "id": "Q13491-1", "name": "Neuronal membrane glycoprotein M6-b", "aln": "-----------------------------------------------------MKPAMETAAEENTEQSQERK----------------------------------------------GCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALAGTVAILEQHFSTNASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVK-ELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSPQTNGTTGVEQICVDIRQYG-IIPWNAFPG--KICGSALENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCTKF-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJK1-1", "uniprot_id": "GPM6B_RAT", "id": "Q9JJK1-1", "name": "Neuronal membrane glycoprotein M6-b", "aln": "-----------------------------------------------------MKPAMETAAEENTEQSQERK----------------------------------------------GCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALAGTVAILEQHFSTNTSDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVK-ELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSPQSNGTSGVEQICVDVRQYG-IIPWNAFPG--KICGSALENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCPKF-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35803-1", "uniprot_id": "GPM6B_MOUSE", "id": "P35803-1", "name": "Neuronal membrane glycoprotein M6-b", "aln": "-----------------------------------------------------MKPAMETAAEENTEQSQERKVNSRAEMEIGRYHWMYPGSKN------HQYRPVPNLGDRAGPLSSPGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALAGTVAILEQHFSTNTSDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVK-ELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSPQSNGTSGVEQICVDVRQYG-IIPWNAFPG--KICGSALENICNTNEFYMSYHLFIVACAGAGATVIALIHFLMILSSNWAYLKDASKMQAYQDIKAKEEQELQDIQSRSKEQLNSYT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13A7D1-1", "uniprot_id": "A0AB13A7D1_DANRE", "id": "A0AB13A7D1-1", "name": "", "aln": "---------------------------------------------------------METSYDETEDERQEKR----------------------------------------------GCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALTGTMTILENHFSRITADHAMLTDIVQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVK-ELHSEFKTTVCGRCISGMFVFLTYILGIAWLGVFGFSAVPVFLFYNMWSTCAAMRSPVANLTS-IDSICVDVRQYG-IIPWNATPG--KACGSTLGDICNTNEFYLSYHLYIVACAGAGATVIALIHFLMILSANWAYLKDASHLHSYQDIKLKEERELQDIQSRSKDCLHSYS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PGC0-1", "uniprot_id": "M9PGC0_DROME", "id": "M9PGC0-1", "name": "", "aln": "MFCSNAERGPLSWCHWHPAFGIWSKACGPKPRWQSTLELHSVWHRHRGTSALCSMPGKGNNRDRIRDPREEILLETNFEDDGGVLTRAYNGNPYNPTIQNRRRNSYRSDHSLDRYTERGGEGECCQSCMARIPYATLIATLMCLLGVGIFCFTMYRGASLTVIMVDQVFHLR-----LIWIEAVQMIFVIIGAG--MAALGFMILFVGFLATGATRYKVYRAWRSRVGGRISCAVLMGITYLLNFVWSLILCFLVVVTFIYTMFWNMCTSVEHSQS---------CIDLTQFHFMFPPNTKLEDMKVCEKYEIKAFCKDGVENAEVMFILATLSTLLVLLSLVHYLMCLSANYAHIRDHEKFQELQEIQNLNELEYS---ATSKDRF----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : :* * *** .*:. :***:*:**::*: **.:** : . : *: :::: * :: * :** * . : *:::* ** :*.*.: ::: ::: . ** ..::: :**:*...* :: * .* .*:: :*. * :. . : *:*: *: ::* *: * * . . .: . : ::*:* .: .:::*: ::* : *:* :: .: . .: ", "identical_positions": 53, "similar_positions": 98, "identity": "13.55%" }, { "cls_id": "homologset.agr.RGD:620583", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHI7-1", "uniprot_id": "ELOV5_MOUSE", "id": "Q8BHI7-1", "name": "Very long chain fatty acid elongase 5", "aln": "-------------------------------------------MEHFDASLSTYFKAFLGPRDTR-VKGWFLLDNYIPTFVCSVIYLLIVWLGPKYMKNR--QPFSCRGILQLYNLGLTLLSLYMFYELVTGVWEGKYNF-FCQGTRSAGESDMKIIRVLWWYYFSKLIEFMDTFFFILRKNNHQITVLHVYHHATMLNIWWFVMNWVPCGHSYFGATLNSFIHVLMYSYYGLSSIPSMRPYLWWKKYITQGQLVQFVLTIIQTTCGVFWP----------------CSFPLGWLFFQIGYMISLIALFTNFYIQTYNKKGASRRKDHLKGHQNGSVAAVNGHTNSFPSLENSVKPRKQRKD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYP7-1", "uniprot_id": "ELOV5_HUMAN", "id": "Q9NYP7-1", "name": "Very long chain fatty acid elongase 5", "aln": "-------------------------------------------MEHFDASLSTYFKALLGPRDTR-VKGWFLLDNYIPTFICSVIYLLIVWLGPKYMRNK--QPFSCRGILVVYNLGLTLLSLYMFCELVTGVWEGKYNF-FCQGTRTAGESDMKIIRVLWWYYFSKLIEFMDTFFFILRKNNHQITVLHVYHHASMLNIWWFVMNWVPCGHSYFGATLNSFIHVLMYSYYGLSSVPSMRPYLWWKKYITQGQLLQFVLTIIQTSCGVIWP----------------CTFPLGWLYFQIGYMISLIALFTNFYIQTYNKKGASRRKDHLKDHQNGSMAAVNGHTNSFSPLENNVKPRKLRKD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q920L7-1", "uniprot_id": "ELOV5_RAT", "id": "Q920L7-1", "name": "Very long chain fatty acid elongase 5", "aln": "-------------------------------------------MEHFDASLSTYFRALLGPRDTR-VKGWFLLDNYIPTFVCSAIYLLIVWLGPKYMKNR--QPFSCRGILVVYNLGLTLLSLYMFYELVTGVWEGKYNF-FCQGTRSAGESDMKVIRVLWWYYFSKLIEFMDTFFFILRKNNHQITVLHVYHHATMLNIWWFVMNWVPCGHSYFGATLNSFIHVLMYSYYGLSSVPSMRPYLWWKKYITQGQLVQFVLTIIQTSCGVIWP----------------CSFPLGWLYFQIGYMISLIALFTNFYIQTYNKKGASRRKEHLKGHQNGSMTAVNGHTNNFASLENSVTSRKQRKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AA52Z2T5-1", "uniprot_id": "A0AA52Z2T5_DANRE", "id": "A0AA52Z2T5-1", "name": "Elongation of very long chain fatty acids protein 5", "aln": "-------------------------------------------METFSHRVNSYIDSWMGPRDLR-VRGWFLLDDYIPTFIFTVMYLLIVWMGPKYMKNR--QAYSCRALLVPYNLCLTLLSLYMFYELVMSVYQGGYNF-FCQNTHSGGDADNRMMNVLWWYYFSKLIEFMDTFFFILRKNNHQITFLHVYHHATMLNIWWFVMNWVPCGHSYFGATFNSFIHVLMYSYYGLSAVPALRPYLWWKKYITQGQLVQFVLTMFQTSCAVVWP----------------CGFPMGWLYFQISYMVTLILLFSNFYIQTYKKRSGSRKSD----YPNG---SVNGHTNGVMSSE-KIKHRKARAD---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25358-1", "uniprot_id": "ELO2_YEAST", "id": "P25358-1", "name": "Fatty acid elongase 2", "aln": "MNSLVTQYAAPLFERYPQLHD--------YLPTLERPFFNISLWEHFDDVVTRVTNGRFVPSEFQFIAGELPLSTLPPVLYAITAYYVIIFGGRFLLSKS--KPFKLNGLFQLHNLVLTSLSLTLLLLMVEQLVPIIVQHGLYFAICNIGAWTQPLVTLYYMNYIVKFIEFIDTFFLVLKHK--KLTFLHTYHHGATALLCYTQLMGTTS-ISWVPISLNLGVHVVMYWYYFLAARGIR---VWWKEWVTRFQIIQFVLDIGFIYFAVYQKAVHLYFP--ILPHCGDCVGSTTATFAGCAIISSYLVLFISFYINVYKRKGTKTSRVVKRAHGGVAAKVNEYVNVDLKNVPTPSPSPKPQHRRKR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39540-1", "uniprot_id": "ELO1_YEAST", "id": "P39540-1", "name": "Fatty acid elongase 1", "aln": "---MVSDWKNFCLEKASRFR-----------PTIDRPFFNIYLWDYFNRAVGWATAGRFQPKDFEFTVGKQPLSEPRPVLLFIAMYYVVIFGGRSLVKSC--KPLKLRFISQVHNLMLTSVSFLWLILMVEQMLPIVYRHGLYFAVCNVESWTQPMETLYYLNYMTKFVEFADTVLMVLKHR--KLTFLHTYHHGATALLCYNQLVGYTA-VTWVPVTLNLAVHVLMYWYYFLSASGIR---VWWKAWVTRLQIVQFMLDLIVVYYVLYQKIVAAYFKNACTPQCEDCLGSMTAIAAGAAILTSYLFLFISFYIEVYKRGSASGKKKINKNN---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40319-1", "uniprot_id": "ELO3_YEAST", "id": "P40319-1", "name": "Fatty acid elongase 3", "aln": "MNTTTSTVIAAVADQFQSLNSSSSCFLKVHVPSIENPFG-IELWPIFSKVFEYFSG--YPAEQFEFIHNKTFLANGYHAVSIIIVYYIIIFGGQAILRALNASPLKFKLLFEIHNLFLTSISLVLWLLMLEQLVPMVYHNGLFWSICSKEAFAPKLVTLYYLNYLTKFVELIDTVFLVLRRK--KLLFLHTYHHGATALLCYTQLIGRTS-VEWVVILLNLGVHVIMYWYYFLSSCGIR---VWWKQWVTRFQIIQFLIDLVFVYFATYTFYAHKYLDG-ILPNKGTCYGTQAAAAYGYLILTSYLLLFISFYIQSYKKGGKKTVKKESEVSGSVASGSSTGVKTSNTKVSSRKA----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . . : . . * .. * :::: * : .. . . : :** ** :*: :: : . : . : : : *: *::*: **.:::*::. :: .**.***.: : : : .. :. :* :**:** ** *:: :*** ::*: *::**:: : * . : : : ** .***: *:: . . ", "identical_positions": 42, "similar_positions": 78, "identity": "11.51%" }, { "cls_id": "homologset.agr.RGD:620584", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00536-1", "uniprot_id": "CDK16_HUMAN", "id": "Q00536-1", "name": "Cyclin-dependent kinase 16", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MDRMKKIKRQLSMTLRGGRGIDK------------TNGAPEQIGLDESGGGGGSDPGE----------APTRAAPGELRSARGPLSSAP------EIVHEDLKMGSDGESDQASATSSDEVQSPVRVR-----MRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSP-----IFDKPLSRRLRRVSLSEIGFGKLET-----------YIKLDKLGEGTYATVYKGKS--------------KLTDNLVALKEIRLEHEEGAPCTAIREVSLLKD-------------------------------------LKHANIVTLHDIIHTEKSLT-------LVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRG----------LAYCHRQKVLHRDLK---------PQNLLINE-------RGELKLADFGLARAKSIPTKTYSN-------------EVVTLWYRPPDILLGSTDYS-----------TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILG--TPTEETWPGILSNEEFKTYNYP-----KYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMK---HPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDS---GRPAFRVVDTEF------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04735-1", "uniprot_id": "CDK16_MOUSE", "id": "Q04735-1", "name": "Cyclin-dependent kinase 16", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MDRMKKIKRQLSMTLRGGRGIDK------------TNGVPEQIGLDESGGGGGSDLGE----------APTRIAPGELRSVRGPLSSAP------EIVHEDMKMGSDGESDQASATSSDEVQSPVRVR-----MRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSP-----IFDKPLSRRLRRVSLSEIGFGKLET-----------YIKLDKLGEGTYATVYKGKS--------------KLTDNLVALKEIRLEHEEGAPCTAIREVSLLKD-------------------------------------LKHANIVTLHDIIHTEKSLT-------LVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRG----------LAYCHRQKVLHRDLK---------PQNLLINE-------RGELKLADFGLARAKSIPTKTYSN-------------EVVTLWYRPPDILLGSTDYS-----------TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILG--TPTEETWPGILSNEEFRTYNYP-----KYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDARK---HPFFLSLGERIHKLPDTTSIFALKEVQLQKEANIRSTSMPDS---GRPAFRVVDTEF------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9Q3R1-1", "uniprot_id": "A0A8M9Q3R1_DANRE", "id": "A0A8M9Q3R1-1", "name": "cyclin-dependent kinase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MDRMRKIKRQLSLTLRGGNSGDKSLSETISSQDTGAHSDSEAMPVGGSGGLRGSVRGSGGSFSMHSLLQSYSSALRRPRSLGRSLSSYLNHTTRLEIVHEDVKMGSDGESDQASATSSDEVHSPVRVR-----LRNNPGRKISTEDINKRLSLPADIRLPDGYLEKFSLNSP-----LFDKPLSRRLRRVSLSEIGFGKLET-----------YVKLDKLGEGTYATVYKGRS--------------KLTDNLVALKEIRLEHEEGAPCTAIREVSLLKD-------------------------------------LKHANIVTLHDIIHTQKSLT-------LVFEYLDKDLKQYLDDCGNSIHMHNVKLFLFQLLRG----------LNYCHRRKVLHRDLK---------PQNLLIND-------RGELKLADFGLARAKSIPTKTYSN-------------EVVTLWYRPPDILLGSTDYS-----------TQIDMWGVGCIFYEMSTGRPLFPGSTVEEELHFIFKLLG--TPTEETWPGITSNEEFISYNYP-----RYRADCLHNHTPRLDNDGVELLSKLLQFEGKKRIAAEEAMR---HPYFHCLGERLLTLPDTTSIFALQEIQLEKEPGMRTNSLSESEL-LQRCLRFRHTLVNSISQRQSLLF-------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5D006-1", "uniprot_id": "UBP11_RAT", "id": "Q5D006-1", "name": "Ubiquitin carboxyl-terminal hydrolase 11", "aln": "MAAVAADPAAAAVPASAEDRETQPEAMPDLDQQWRQIGNGRERPLRAGESWFLVEKHWYKQWEAYVKGGDQDASTFPGSINNSGLFEDQISWHLRERLVEGDDYVLLPAPAWNYLVSWYGLKDDQPPIERKVIELPGIRKVEVYPIELLLVQHSDMETALTIQFSYSDSVDLVLQTAR--EQFLVEPQEDTRLWTKNSEGSLDRLCNTQITLLDACLETGQLVIMETRNKDGTWPSAQLCGMNNMPDEDEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADLVKQTWSGYHRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCNGAGRPDLEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVCSRRVLEVFFVPMDPRRKPEQHRVVVPKKGNISDLCVALSTHTSVAPDKMIVADVFSHRFYKLYQLEDPLSGILDRDDIFVYEVTGRIEPVEGSRDDIVVPVYLRERTPSRDYNNSYYGLILFGHPLLVSVPRDRFSWEGLYNILMYRLSRYVTKPTSDDDDGDEKGDENEDEDVEDDSSSEEEKEEMSGPTDNDGTQESEQEQAGTSSGVTGRCPSLLDNSLHTSQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEAQTQPYIAMDWEPEMKRRYYDEVEAEGYVKHDCVGYMLKKNPVQLKECIKLFTTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSFSKFSREKLDTLVQFPIRDLDFSEFVIKPKNESAPDLYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVGRRQSQTASSETPTSPASSSTPNSDIMDVN", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .:: *:: : . . * .. : .. . . . . . *. . .* .:: *. * .. :. .: ::*.:: : : .: *::* * .* . .*.:.* : .. . . :. : :..:: :.: . :*: : :: : .*::: : *. : :* . * :: * :. :: .:. *. :**: * *:.** * : *..*:: **.: .* * * .. :. .:: :: . : *.:. ** : : **:. .* :: : *:* : **. .: * : . : : *.** . *. .: * : : : . :* .::*. : : . *. . * * ..: : : :: :* : . : * * * .: :*:: :: : :*:: . :: ... .:: * *: : : : ..:. . : . . . ", "identical_positions": 63, "similar_positions": 198, "identity": "6.83%" }, { "cls_id": "homologset.agr.RGD:620585", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920L5-1", "uniprot_id": "ELOV6_MOUSE", "id": "Q920L5-1", "name": "Very long chain fatty acid elongase 6", "aln": "------------------------------------------MNMSVLTLQEY----EFEKQFNENEAIQWMQENWKKSFLFSALYAAFIFGGRHLMNKR--AKFELRKPLVLWSLTLAVFSIFGALRTGAYMLYILMTKGLKQSVCDQSFYN-GPVSKFWAYAFVLSKAPELGDTIFIILRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQMLMGCVINYLVFN------WMQ----HDNDQCYSHFQNIFWSSLMYLSYLVLFCHFFFEAYIG----KVK--KATKAE------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q920L6-1", "uniprot_id": "ELOV6_RAT", "id": "Q920L6-1", "name": "Very long chain fatty acid elongase 6", "aln": "------------------------------------------MNMSVLTLQEY----EFEKQFNENEAIQWMQENWKKSFLFSALYAAFIFGGRHLMNKR--AKFELRKPLVLWSLTLAVFSIFGALRTGAYMLYILMTKGLKQSVCDQSFYN-GPVSKFWAYAFVLSKAPELGDTIFIILRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQMLMGCVINYLVFN------WMQ----HDNDQCYSHFQNIFWSSLMYLSYLLLFCHFFFEAYIG----KVK--KATKAE------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H5J4-1", "uniprot_id": "ELOV6_HUMAN", "id": "Q9H5J4-1", "name": "Very long chain fatty acid elongase 6", "aln": "------------------------------------------MNMSVLTLQEY----EFEKQFNENEAIQWMQENWKKSFLFSALYAAFIFGGRHLMNKR--AKFELRKPLVLWSLTLAVFSIFGALRTGAYMVYILMTKGLKQSVCDQGFYN-GPVSKFWAYAFVLSKAPELGDTIFIILRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQMLMGCVVNYLVFC------WMQ----HD--QCHSHFQNIFWSSLMYLSYLVLFCHFFFEAYIG----KMR--KTTKAE------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PC64-1", "uniprot_id": "ELOV6_DANRE", "id": "Q6PC64-1", "name": "Very long chain fatty acid elongase 6", "aln": "--------------------------------------------MSVLALQEY----EFERQFNEDEAIRWMQENWKKSFLFSALYAACILGGRHVMKQR--EKFELRKPLVLWSLTLAAFSIFGAIRTGGYMVNILMTKGLKQSVCDQSFYN-GPVSKFWAYAFVLSKAPELGDTLFIVLRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYLVHAVMYSYYALRAAGFKISRKFAMFITLTQITQMVMGCVVNYLVYL------WMQ----QGQ-ECPSHVQNIVWSSLMYLSYFVLFCQFFFEAYIT----KRKSNAAKKSQ------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV87-1", "uniprot_id": "ELOV6_DROME", "id": "Q9VV87-1", "name": "Very long chain fatty acid elongase 6", "aln": "-----------------------------------------MINMDISVTPNYSYIFDFENDFIHQRTRKWMLENWTWVFYYCGIYMLVIFGGQHFMQNR--PRFQLRGPLIIWNTLLAMFSIMGAARTAPELIHVLRHYGLFHSVCVPSYIEQDRVCGFWTWLFVLSKLPELGDTIFIVLRKQPLIFLHWYHHITVLIYSWFSYTEYTSSARWFIVMNYCVHSVMYSYYALKAARFNPPRFISMIITSLQLAQMIIGCAINVWANG------FLKT---HGTSSCHISQRNINLSIAMYSSYFVLFARFFYKAYLAPGGHKSRRMAASLAAQNVVKQSSSPQQASESSKFIGAGEDQAAYLRKAKAQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25358-1", "uniprot_id": "ELO2_YEAST", "id": "P25358-1", "name": "Fatty acid elongase 2", "aln": "MNSLVTQYAAPLFERYPQLHD--------YLPTLERPFFNISLWEHFDDVVTRVTNGRFVPSEFQFIAGELPLSTLPPVLYAITAYYVIIFGGRFLLSKS--KPFKLNGLFQLHNLVLTSLSLTLLLLMVEQLVPIIVQHGLYFAICNIGAWT--QPLVTLYYMNYIVKFIEFIDTFFLVLKHKKLTFLHTYHHGATALLCYTQLMGTTSISWVPISLNLGVHVVMYWYYFLAARGIR--VWWKEWVTRFQIIQFVLDIGFIYFAVYQKAVHLYFP--ILPHCGDCVGSTTATFAGCAIISSYLVLFISFYINVYKRKG--TKTSRVVKRAHGGVAAKVNEYVNVDLKNVPTPSPSPKPQHRRKR---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39540-1", "uniprot_id": "ELO1_YEAST", "id": "P39540-1", "name": "Fatty acid elongase 1", "aln": "---MVSDWKNFCLEKASRFR-----------PTIDRPFFNIYLWDYFNRAVGWATAGRFQPKDFEFTVGKQPLSEPRPVLLFIAMYYVVIFGGRSLVKSC--KPLKLRFISQVHNLMLTSVSFLWLILMVEQMLPIVYRHGLYFAVCNVESWT--QPMETLYYLNYMTKFVEFADTVLMVLKHRKLTFLHTYHHGATALLCYNQLVGYTAVTWVPVTLNLAVHVLMYWYYFLSASGIR--VWWKAWVTRLQIVQFMLDLIVVYYVLYQKIVAAYFKNACTPQCEDCLGSMTAIAAGAAILTSYLFLFISFYIEVYKRGS--ASGKKKINKNN------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40319-1", "uniprot_id": "ELO3_YEAST", "id": "P40319-1", "name": "Fatty acid elongase 3", "aln": "MNTTTSTVIAAVADQFQSLNSSSSCFLKVHVPSIENPFG-IELWPIFSKVFEYFSG--YPAEQFEFIHNKTFLANGYHAVSIIIVYYIIIFGGQAILRALNASPLKFKLLFEIHNLFLTSISLVLWLLMLEQLVPMVYHNGLFWSICSKEAFA--PKLVTLYYLNYLTKFVELIDTVFLVLRRKKLLFLHTYHHGATALLCYTQLIGRTSVEWVVILLNLGVHVIMYWYYFLSSCGIR--VWWKQWVTRFQIIQFLIDLVFVYFATYTFYAHKYLDG-ILPNKGTCYGTQAAAAYGYLILTSYLLLFISFYIQSYKKGG--KKTVKKESEVSGSVASGSSTGVKTSNTKVSSRKA-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . . * *:**: .: :::. : . *: .*: :: :: ** ::* : : * *: **.:::*::: * *** *** :. : .: . .: : :* ** :** ** * : :. :* *: *:::. . . :: * . : **:.** *: : * . ", "identical_positions": 39, "similar_positions": 66, "identity": "10.6%" }, { "cls_id": "homologset.agr.RGD:620586", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1W3-1", "uniprot_id": "RN103_MOUSE", "id": "Q9R1W3-1", "name": "E3 ubiquitin-protein ligase RNF103", "aln": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNVEHLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWNNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYDYSLRLLRYSNTTTLASWVRADWMFYTSHPALFLSTYLGHGLLIDYFEKKRRRSNN-DEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVDSDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSESSQDTENDSDSDNMDTFSSSKDIFEDKQSVVHSSPGRTSHCDTEACSCANK-CESSPCERKRRSYGSHNTDEDMEPDWLTWPAGTLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQQQPLSNDVPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EPZ8-1", "uniprot_id": "RN103_RAT", "id": "Q9EPZ8-1", "name": "E3 ubiquitin-protein ligase RNF103", "aln": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNVEHLKEEWNKSDQYWVKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWNNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLRLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRSNN-DEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVDSDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGAQSEEEMSESSQDTENDSDSDNTDTFSSSKDVFEDKQ-NVHSSPGRTSRCDTEACSCANK-CVSSPCERKRRSYGSHNTKEDMEPDWLTWPAGTLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQQQPLSNDAPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00237-1", "uniprot_id": "RN103_HUMAN", "id": "O00237-1", "name": "E3 ubiquitin-protein ligase RNF103", "aln": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNAEHLKEEWNKSDQYWLKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWDNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLKLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRNNNNDEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVESDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSEGSQDTENDSESENTDTLSSEKEVFEDKQSVLHNSPGTASHCDAEACSCANKYCQTSPCERKGRSYGSYNTNEDMEPDWLTWPADMLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQHQPLSNDVPS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************************************************************************************************************************************************************************************************************.**************:************************************:*******************************************************************************************************************:***:*********************:**************************.** **********************************:******************************************.********.********:*:* **:**.*::***** :*.*** :*:**:******** * :****** *****:**.************. ************************************************************:******.**", "identical_positions": 649, "similar_positions": 27, "identity": "94.74%" }, { "cls_id": "homologset.agr.RGD:620587", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q924T4-1", "uniprot_id": "LFNG_RAT", "id": "Q924T4-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe", "aln": "-----------MLQRCGRRLLLALVGALLACLLVLTAD---------PPPTPVPAE----RGRRALRS-LAGSSGAAPGPGS-RAAVDPGVLVREVHSLSE------------YFSLLTRARRDADPPPGVASRQGDGHPRPPAEVLSPRDVFIAVKTTRKFHRARLDLLFETWISRHKEMTFIFTDGEDEALAKHTG-NVVLTNCSAAHSRQALSCKMAVEYDRFIESGKKWFCHVDDDNYVNLRALLRLLASYPHTQDVYIGKPSLDRPIQA-TERISEHRVRPVHFWFATGGAGFCISRGLALKMGPWASGGHFMSTAERIRLPDDCTIGYIVEALLGVPLIRSGLFHSHLENLQQVPTTELHEQVTLSYGMFENKRNAVHIKGPFSVEADPSRFRSIHCHLYPDTPWCPRTAIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09010-1", "uniprot_id": "LFNG_MOUSE", "id": "O09010-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe", "aln": "-----------MLQRCGRRLLLALVGALLACLLVLTAD---------PPPTPMPAE----RGRRALRS-LAGSSGGAPASGS-RAAVDPGVLTREVHSLSE------------YFSLLTRARRDADPPPGVASRQGDGHPRPPAEVLSPRDVFIAVKTTRKFHRARLDLLFETWISRHKEMTFIFTDGEDEALAKLTG-NVVLTNCSSAHSRQALSCKMAVEYDRFIESGKKWFCHVDDDNYVNLRALLRLLASYPHTQDVYIGKPSLDRPIQA-TERISEHKVRPVHFWFATGGAGFCISRGLALKMGPWASGGHFMSTAERIRLPDDCTIGYIVEALLGVPLIRSGLFHSHLENLQQVPTTELHEQVTLSYGMFENKRNAVHIKGPFSVEADPSRFRSVHCHLYPDTPWCPRSAIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NES3-1", "uniprot_id": "LFNG_HUMAN", "id": "Q8NES3-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe", "aln": "-----------MLKRCGRRLLLALAGALLACLLVLTAD---------PPPPPLPAE----RGRRALRS-LAGPAGAAPAPGLGAAAAAPGALVRDVHSLSE------------YFSLLTRARRDAGPPPGAAPRPADGHPRPLAEPLAPRDVFIAVKTTKKFHRARLDLLLETWISRHKEMTFIFTDGEDEALARHTG-NVVITNCSAAHSRQALSCKMAVEYDRFIESGRKWFCHVDDDNYVNLRALLRLLASYPHTRDVYVGKPSLDRPIQA-MERVSENKVRPVHFWFATGGAGFCISRGLALKMSPWASGGHFMNTAERIRLPDDCTIGYIVEALLGVPLIRSGLFHSHLENLQQVPTSELHEQVTLSYGMFENKRNAVHVKGPFSVEADPSRFRSIHCHLYPDTPWCPRTAIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JHF2-1", "uniprot_id": "LFNG_DANRE", "id": "Q8JHF2-1", "name": "Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe", "aln": "-----------MLKTYRGKVVVSLAGATVTCLGFLLFL---------SQHQRIQADGMQNESEVGLRS-LQSLGDSETDDGA-----QPEQNAK--KGFSA------------YFSKLTRSRREADKP---SEAPGAATDAPPAEDISADDIFIAVKTTKKFHRSRLDLLLDTWISRNMRQTYIFTDGEDEELKKKIGSHAINTNCSAAHSRQALSCKMAVEYDKFIESGKKWFCHVDDDNYVNTKTLVKLLSNYPHTQDMYIGKPSLDRPIEA-TERLGDNKMRPVNFWFATGGAGFCISRGLALKMSPWASGGHFMNTAEKIRLPDDCTIGYIIESVLGVSLTRSSLFHSHLENLQQVSKSEVHKQITLSYGMFENKRNIINMKGAFSVEEDPSRFKSVHCLLYPDTPWCPPQVAY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24342-1", "uniprot_id": "FNG_DROME", "id": "Q24342-1", "name": "Fringe glycosyltransferase", "aln": "MMSLTVLSPPQRFKRILQAMMLAVAVVYMTLLLYQSAYGYPGIQVPHSQVDALASEAVTTHRDQLLQDYVQSSTPTQPGAGAPAASPTTVIIRKDIRSFNFSDIEVSERPTATLLTELARRSRNGELLRDLSQRAVTATPQPPVTELD--DIFISVKTTKNYHDTRLALIIKTWFQLARDQTWFFTDTDDHYYQEKTKGHLINTKCSQGHFRKALCCKMSAELDVFLESGKKWFCHFDDDNYVNVPRLVKLLDEYSPSVDWYLGKPSISSPLEIHLDSKNTTTNKKITFWFATGGAGFCLSRALTLKMLPIAGGGKFISIGDKIRFPDDVTMGFIIEHLLKVPLTVVDNFHSHLEPMEFIRQDTFQDQVSFSYAHMKNQWNVIKVDG-FDMKTDPKRFYSLHCQLFPYFSFCPPR---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :::::. . :: * . : :: . *:. : . . * . : :.:. :: *:* *:. : . * . : *:**:****:::* :** *::.**:. *::*** :*. . : : *:** .* *:**.***:.* * *:***:*****.******* *::** .*. : * *:****:. *:: : . : : ***********:**.*:*** * *.**:*:. .::**:*** *:*:*:* :* *.* . ****** :: : .:.*:::**. ::*: * :::.* *.:: **.** *:** *:* .:** ", "identical_positions": 122, "similar_positions": 119, "identity": "29.19%" }, { "cls_id": "homologset.agr.RGD:620588", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10810-1", "uniprot_id": "CD14_MOUSE", "id": "P10810-1", "name": "Monocyte differentiation antigen CD14", "aln": "MERVLGLLLL--LLVHASPAPPEPCELDEES----CSCNFSDPKPDWSSAFNCLGAADVELYGGGRSLEYLLKRVDTEADLGQFTDIIKSLSLKRLTVRAARIPSRILFGALRVLGISGLQELTLENLEVTGTAPPPLLEATGPDLNILNLRNVSWATRDAWLAELQQWLKPGLKVLSIAQAHSLNFSCEQVRVFPALSTLDLSDNPELGERGLISALCPLKFPTLQVLALRNAGMETPSGVCSALAAARVQLQGLDLSHNSLRDAAG--APSCDWPSQLNSLNLSFTGLKQVPKGLPAKLSVLDLSYNRLDRNPSPDELPQVGNLSLKGNPFLD---SESHSEKFNSGVVTAGAPSSQAVALSGTLALLLGDRLFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63691-1", "uniprot_id": "CD14_RAT", "id": "Q63691-1", "name": "Monocyte differentiation antigen CD14", "aln": "MKLMLGLLLLPLTLVHASPATPEPCELDQDEESVRCYCNFSDPQPNWSSAFLCAGAEDVEFYGGGRSLEYLLKRVDTEANLGQYTDIIRSLPLKRLTVRSARVPTQILFGTLRVLGYSGLRELTLENLEVTGTALSPLLDATGPDLNTLSLRNVSWATTDTWLAELQQWLKPGLKVLSIAQAHSLNFSCKQVGVFPALATLDLSDNPELGEKGLISALCPHKFPTLQVLALRNAGMETTSGVCSALAAARVPLQALDLSHNSLRDTAG--TPSCDWPSQLNSLNLSFTGLEHVPKGLPAKLSVLDLSYNRLDRKPRPEELPEVGSLSLTGNPFLH---SESQSEAYNSGVVIATALSPGSAGLSGTLALLLGHRLFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08571-1", "uniprot_id": "CD14_HUMAN", "id": "P08571-1", "name": "Monocyte differentiation antigen CD14", "aln": "MERASCLLLLLLPLVHVSATTPEPCELDDED--FRCVCNFSEPQPDWSEAFQCVSAVEVEIHAGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKELTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQAHSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: **** ***.*.:.*******::. * ****:*:*:**.** * .* :**::.** .** :*****::*: *::* :::* ::**** :*::*:::*.*:****. * *:*****:*::*** . *:*** *. * ******** :*********************** ***:** .****::******* ***:**::**** ***::* *****:****.:***:***** * :.********* :.. :* * *.* ********:**::********* ***** ***:* * *:***:*..*:* ***** : .:. ***** * * *. :..:****.** * * *.", "identical_positions": 222, "similar_positions": 86, "identity": "58.89%" }, { "cls_id": "homologset.agr.RGD:620589", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K5A3-1", "uniprot_id": "CST11_RAT", "id": "Q8K5A3-1", "name": "Cystatin-11", "aln": "MMARLWKTTWFLLAILVALVAFSYQVKRKTFIRVEEVNALESSVKETLEYVTEEYNKKSEDLYNFRILRILKIEKQMTNHMEFHITVEMQRTTCLKTEKNLCNVQEGELHKQIQCYFSVYVIPWLEVFKMLKKNCTNSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D269-1", "uniprot_id": "CST11_MOUSE", "id": "Q9D269-1", "name": "Cystatin-11", "aln": "MAAGSWKATRLLLAILVALVAFSYQVKRKTFIRIEEVSALESSVKETLEYVTDEYNKKSEDLYNFRILRILKIMKQVTGHLEYHITVEMQRTTCLKTETSLCDIQKGELHKKIQCYFSVYAIPWVEVFKILKKNCTDIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H112-1", "uniprot_id": "CST11_HUMAN", "id": "Q9H112-1", "name": "Cystatin-11", "aln": "MMAEPWQALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDKYHFRIFRVLKVQRQVTDHLEYHLNVEMQWTTCQKPETTNCVPQERELHKQVNCFFSVFAVPWFEQYKILNKSCSSD-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *:: :*****::*:*:.**.::***: :.** *:*. .*::*:::*::***:*:* *:***:*:**: :*:*.*:*:*:.**** *** *.*.. * *: ****:::*:***:.:**.* :*:*:*.*:. ", "identical_positions": 65, "similar_positions": 55, "identity": "46.76%" }, { "cls_id": "homologset.agr.RGD:62059", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63572-1", "uniprot_id": "TESK1_RAT", "id": "Q63572-1", "name": "Dual specificity testis-specific protein kinase 1", "aln": "----------------------------------------MAGERPPLRGPGPG--ETPVEGP---GGAGGGPGRGRP--------------SSYRALRSAVSSLARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLS-SPEPLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVR-REDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSARAPFTEITQHLEQILEQLPEPTPLAKMPLAKAPLTYNQGSVPRGGPSATLPRSDP-----------------------------RLSRSRSDLFLPPSPESPPSWGDNLTRVNPFSLREDLRGGKIKLLDTPCKPATPLPLVPPSP-LTSTQLPLVASPESLVQPETPVRRCR-------SLPSSPELPRRMETALPGP--GPSPVGPSTEERMDCEGSS--------------PEPEPPGPAPQLP----------------------LAVATDN-----FISTCS-----SASQPWSARPGPSLNNNPPAVVVNSPQGWAREPWNRAQHSLPRAAALERTE--------------------------------PSPPPSAPREQEEGLPCPGCCLSPFSFGFLSMCPRPTP------AVARYRNLNC-----EAGSLLCHRGHHAKPPTPS-----LQLPGARS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70146-1", "uniprot_id": "TESK1_MOUSE", "id": "O70146-1", "name": "Dual specificity testis-specific protein kinase 1", "aln": "----------------------------------------MAGERPPLRGPGPG--EAPGEGP---GGAGGGPGRGRP--------------SSYRALRSAVSSLARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLS-SPEPLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVR-REDRGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSTRAPFTEITQHLEQILEQQPEATPLAKPPLTKAPLTYNQGSVPRGGPSATLPRPDP-----------------------------RLSRSRSDLFLPPSPESPPSWGDNLTRVNPFSLREDLRGGKIKLLDTPCKPATPLPLVPPSP-LTSTQLPLVTTPDILVQPETPVRRCR-------SLPSSPELPRRMETALPGP--GPSPMGP-TEERMDCEGSS--------------PEPEPPGLAPQLP----------------------LAVATDN-----FISTCS-----SASQPWSPRSGPPLNNNPPAVVVNSPQGWAREPWNRAQHSLPRAAALERTE--------------------------------PSPPPSAPREPEEGLPCPGCCLGPFSFGFLSMCPRPTP------AVARYRNLNC-----EAGSLLCHRGHHAKPPTPS-----LQLPGARS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15569-1", "uniprot_id": "TESK1_HUMAN", "id": "Q15569-1", "name": "Dual specificity testis-specific protein kinase 1", "aln": "----------------------------------------MAGERPPLRGPGPGPGEVPGEGPPGPGGTGGGPGRGRP--------------SSYRALRSAVSSLARVDDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLS-SPEPLSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKNCLVR-REDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGDDCPLPFLLLAIHCCNLEPSTRAPFTEITQHLEWILEQLPEP-----APLTRTALTHNQGSVARGGPSATLPRPDP-----------------------------RLSRSRSDLFLPPSPESPPNWGDNLTRVNPFSLREDLRGGKIKLLDTPSKP--VLPLVPPSP-FPSTQLPLVTTPETLVQPGTPARRCR-------SLPSSPELPRRMETALPGP--GPPAVGPSAEEKMECEGSS--------------PEPEPPGPAPQLP----------------------LAVATDN-----FISTCS-----SASQPWSPRSGPVLNNNPPAVVVNSPQGWAGEPWNRAQHSLPRAAALERTE--------------------------------PSPPPSAPREPDEGLPCPGCCLGPFSFGFLSMCPRPTP------AVARYRNLNC-----EAGSLLCHRGHHAKPPTPS-----LQLPGARS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEW6-1", "uniprot_id": "E7FEW6_DANRE", "id": "E7FEW6-1", "name": "dual-specificity kinase", "aln": "-----------------------------------------MSIFMDQDDLDPEASDSLMHGV-------HGAHRPRP--------------SSYRALRSAVSSLARLDDFIC-EKIGSGFFSEVFKVQHRSTGQVMALKMNTMASNKANMLKEVQLMNRLRHPNILRFVGVCVHEGHLHALTEYINGGNLEQLLN-SDVLLSWSVRINLSLDIARGLQYLHSKGIFHRDLTSKNCLVR-WENGHCTAVVGDFGLAEKIPDHSEEAEKQSLAVVGSPYWMAPEVLRGERYNEKVDVFAYGIILCEIIGRIQADPDFLPRTEDFGLDVEAFRLMVE-DCPAHFFNLAVVCCGMSPDSRPCFSEVVAELEKRESDELQT----DHLESDVQDQMSTSSTPLSRAHSLDIASDP-----------------------------VLCRSKSAVLLPP---SPILNNTTPMRVNPFSQRQDLNGGRIKLFDTPSKSVISLTFTLPPPPDPSSPVPPR-----------SHRRTQ-------SLPCKPQD-IQSLYSTAEKRMNHQSIMDRDVNMLEIGGDS--------------VLTMSSGSIADLSGVLDPNTTGSNPEQEENLELRSQDVLADDSGLPLDLEVLSPNKWRSTEELMDCTSSPDTLDGAVDSTKQFSNGWS-SPVSNGPPSLPPLLDLDNNNSTIPINRPLGWG--------------VNNSNG-ATTPLTPTEQDEVVSCPGCCLAGMSF--PSICTRRAR-------QNPYKNLNG----DAAGKRLLCK---ALPPSPT--EPNITLPGTRT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q613-1", "uniprot_id": "A0A8M9Q613_DANRE", "id": "A0A8M9Q613-1", "name": "dual-specificity kinase", "aln": "---------------------------------------------MDQDE-NQEPCEPPLHAL-------YGPNRIRP--------------SSYRALRSAVSSLARIDDFFC-EKIGSGFFSEVFKVQHRITGQVMALKMNTLASNKANMLREVQLMNRLCHPNILRFLGVCVHEGQLHALTEYINGGNLEQLLD-SDIYLSWTVRIGLSLDIARGLQYLHSKGIFHRDLTSKNCLVR-CENGAFTAVVGDFGLAEKIPDYSDGVEKQPLAVVGSPYWMAPEMLRGELYNEKVDVFAYGIILCEIIARIEADPDILPRTEDFGLDVDTFEHMVG-DCPPSFLQMAVDCCNMNADSRPAFSEIVVMLERIERERVKS----EIPV--ILEPIAIDVSPYRRRSSPCHPCDQ-----------------------------RLSRSQSDMLPPAT--SPCLG--TPARVNPFSLRQDLNGGRIKLFDTPSKSVISLTFTLPPPPDPSASPPLSGSPG----LRGPPRRCR-------SLPCTPELGRQLPFRDQEVEEDRSEELGQETKDKELEGQQ--------------DAVEDSGLVLDLDMVSLERVE----EEEE-----DEEVEKEGQSLTEPMDCSS-----SPDTTEGNVSGKRLISGSSYSSSLQSNGWA-TPISNGPPLLPPLPRLDNNNGVLRPGRPFAWVR-------------LNGYRGPAPEPLPPTEQDDVISCPACCLAGFSF--PSLCLRGAPPSRRGPPRRPYRTFNGGDASTATAKGLLCRGATGLAPSTASCEPGLPLPEAQT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE06-1", "uniprot_id": "Q9VE06_DROME", "id": "Q9VE06-1", "name": "dual-specificity kinase", "aln": "MSLNQHSGPGPPSEICGLSVDQVDSSAASPFIWPSTAGMCTTATTVTTSTNGDATAEAPVKHQPLHNGGWIGNGLPPAPVTRTISSDRLVTGSSCRALRTAVSALYSVDDFVK-EKIGSGFFSEVYKVTHRTTGQVMVLKMNQLRANRPNMLREVQLLNKLSHANILSFMGVCVQEGQLHALTEYINGGSLEQLLANKEVVLSATQKIRLALGIARGMSYVHDAGIFHRDLTSKNVLIRNLANDQYEAVVGDFGLAAKIPVK---SRKSRLETVGSPYWVSPECLKGQWYDQTSDVFSFGIIQCEIIARIEADPDMMPRTASFGLDYLAFVELCPMDTPPVFLRLAFYCCLYDAKSRPTFHDATKKLTLLLEKYEHESSAGASPLSSLELINCSPGGSDSENVTLTPRASVPTVATICTAPAGTLTPRHLQEVDEDGFRFPSKKSASAALPGTPNGSAGSSGFDDHILKSRVRRATQKLEAEILLHRRSLSENIIHFPMHTSPSDKARCHQMQRQRSSTHSPTPPRQLSSVQLPATSIPDPPPLPKPVPAVLTLRKVGDPQYKPTSEKDHNGSKPNPFEALAQLRGVKKILDANPKTYAAGVGDLFSSCFEMLAPFFKELAAMQSKAGAQGGGTSTEETSTGNKASAATPSEPKSLPVSPHMTRKYSAIELRLPQRISNAAPPAVTSAPPPSIALPTDEDDCDDCNSEGEDPDGGGNCADAESSSDDSAVRPSTVPTARKYRANSLYAHPLFRGSNGTSMKSTSTGEFESPTLLKASASTITLTASVGATNSCEDLTESARKSKEQASSGATAAVQALPTPMSGCSTRLVETPVSVSSCTDLELDELKNTCDLNELKNSCEQLPLKTNLTRRDSIESGFFSCFNEESDAAITNNSFGRQLNGIGSLGFGCGGGGNSSNCCYEKLKTQLMLDACVSADSEINDKLASLCRCCYYATSTSNAAVTAAAAAAQQQQQSHLLNDTSSTSSSVLLIDNDPAVIGGNTSSSTALDSMDDLDADIVASRRTHQRRYTCHHALLSGNGSESQMAATASLINRLALDSEIHTLLQRSPFATNQLLYCKNRTSSIYTDSSDDISSLAGSDSLLWDDRSFTALPSTRSAQIAKIVEYFERKRQDSSPPSVHHRNGNGTVAAAVAASALGSNYLSYESRRYSDFKRHLNADGLCFDLDKKPAQQRMMVCEGAVKSKLPIFDKKKQQQGG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . * . ** ****:***:* :*** ****:******:** ** :****.**** : :*: * *:****:*:* *.*** *:****::*:*******:***.***** . ** . :: *:*.**:*: *:* *:********* *:* : ********* *** .*. * .******::** *:*: *::. ***::**: **:*.*: **** :*** .**** :* : * * *: :*. ** ...:*. * : . * . . . : . :* * : . *. ::. * . *:. . . : : .. .: . *: *:* * . : : . : . . . :.. . . .: : . * * : :. * . : : . . . * . .:. : . * . :.: : : ", "identical_positions": 160, "similar_positions": 130, "identity": "13.15%" }, { "cls_id": "homologset.agr.RGD:620591", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61225-1", "uniprot_id": "RAP2B_HUMAN", "id": "P61225-1", "name": "Ras-related protein Rap-2b", "aln": "MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLEGEREVSYGEGKALAEEWS-CPFMETSAKNKASVDELFAEIVRQMNY----------------------------------------------------------------------------------------AAQPNGDEGCCSACVIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61227-1", "uniprot_id": "RAP2B_RAT", "id": "P61227-1", "name": "Ras-related protein Rap-2b", "aln": "MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLEGEREVSYGEGKALAEEWS-CPFMETSAKNKASVDELFAEIVRQMNY----------------------------------------------------------------------------------------AAQPNGDEGCCSACVIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61226-1", "uniprot_id": "RAP2B_MOUSE", "id": "P61226-1", "name": "Ras-related protein Rap-2b", "aln": "MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLEGEREVSYGEGKALAEEWS-CPFMETSAKNKASVDELFAEIVRQMNY----------------------------------------------------------------------------------------AAQPNGDEGCCSACVIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96692-1", "uniprot_id": "O96692_DROME", "id": "O96692-1", "name": "small monomeric GTPase", "aln": "MREFKVVVLGSGGVGKSALTVQFVSGCFIEKYDPTIEDFYRKEIEVDSSPCVLEILDTAGTEQFASMRDLYIKNGHGFIVMYSLTNHQTFQDISSMKNVITRVKGSQPAPILLVANKFDLDCQREVSTAEGNALAQLWD-CPFIEASAKDRINVNEVFATIVREMN-----------------------------------------------------------------------------------------LTQENRQKKNYCCCTLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13856-1", "uniprot_id": "RSR1_YEAST", "id": "P13856-1", "name": "Ras-related protein RSR1", "aln": "MRDYKLVVLGAGGVGKSCLTVQFVQGVYLDTYDPTIEDSYRKTIEIDNKVFDLEILDTAGIAQFTAMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLRIKDSDRVPMVLIGNKADLINERVISVEEGIEVSSKWGRVPFYETSALLRSNVDEVFVDLVRQIIRNEMESVAVKDARNQSQQFSKIESPSTRLPSSAKQDTKQSNNKQSSKGLYNKSSQGQAKVKQSTPVNEKHKPSHAVPKSGSSNRTGISATSQQKKKKKNASTCTIL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*:****:******.****** * :::.******* *** **:*.. ******** **::**:****.* **:::**:.::*::::: ::: : *:* : .*::*:.** ** :* :* ** ::. *. ** *:** : .*:*:*. :**:: :* : .: . *.:*", "identical_positions": 81, "similar_positions": 61, "identity": "29.78%" }, { "cls_id": "homologset.agr.RGD:620592", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C633-1", "uniprot_id": "CABS1_MOUSE", "id": "Q8C633-1", "name": "Calcium-binding and spermatid-specific protein 1", "aln": "MAEDGSPKIYSRPPRDNSKTPTEADIFFGADNTIPKSETTITSEGDHVTSVNDCTPDGDFSTTVN-KLTPTKEKLKLEDDI-EGCLKLTTLPEKEITTPTETPNSKPKGSITENFIPVKIGNTSSPVGTVSLIDFSSNTAKEDIFLTTIDTGEKEVVPTTEFSGTLEDSAADVEDASGFPDESTETDVP---SSATSDAPDDGAVQVTDSFSPEAGVPPSTEKEVTTIPDITNIAEENVTEIKLIVSEDRPKTVTKLSDSEEEKFITVFELTNSAEKAKDNVED-PLNDEESTDGANDWMEKETASEAESHAVLLTAVESRYDFIVTASETDN-VMEESHVNTTDLPENETTESVTNVTEELPSVTSIVDTLKDKEDLSTTNSGLFKLLKEEPDDLMM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68FX6-1", "uniprot_id": "CABS1_RAT", "id": "Q68FX6-1", "name": "Calcium-binding and spermatid-specific protein 1", "aln": "MAEDGSPKIYSRPPRDSSKTPTEADIFFGADNTIPKSETTITSEGDHITSVNDCTADGDFSTTVN-KLTPTKEKLKLEEDI-EASLKSTTLPEKEITTPTETTNSKPKESITENFIPVKIGNISSPVGTVSLIDFSSNMAKEDILLATIDAEDKEVKPTTELSETQEDSSANDEDTSVPPDENTETDVS---SSTSSDVPDDGAVQVTDSFSPESDVPPSTEKEVTTIPD--NVAEDKVTKIDLIVSEDRPKTVTKLSDSEEEKFITVFELTNSAEKAKDNPED-PLTDEEPADGVNTWVEKDAANEAESHAVLLTAVESRYDFVVTASETNSVVVEEPHVDTKNSPEKDAAESVTNVTEEFPSVTSVVEQSGNKEDLSTNDSGIFKLLKEEPDELMM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96KC9-1", "uniprot_id": "CABS1_HUMAN", "id": "Q96KC9-1", "name": "Calcium-binding and spermatid-specific protein 1", "aln": "MAEDGLPKIYSHPPTESSKTPTAATIFFGADNAIPKSETTITSEGDHVTSVNEYMLESDFSTTTDNKLTAKKEKLKSEDDMGTDFIKSTTHLQKEITSLTGTTNSITRDSITEHFMPVKIGNISSPVTTVSLIDFSTDIAKEDILLATIDTGDAEISITSEVSGTLKDSSAGVADAPAFPRKKDEADMSNYNSSIKSNVPADEAVQVTDSTIPEAEIPPAPEESFTTIPDITALEEEKITEIDLSVLEDDTSAVATLTDSDE-KFITVFELTTSAEKDKDKREDTLLTDEETTEGASIWMERDTANEAETHSVLLTAVESRYDFVVPASIATN-LVEESST-EEDLSETDNTETVPKITEPFSGTTSVLDTPDYKEDTSTTETDIFELLKEEPDEFMI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** *****:** :.***** * *******:**************:****: :.*****.: ***..***** *:*: :* ** :****: * *.** .: ****:*:****** **** ********:: *****:*:***: : *: *:*.* * :**:*. *:. * :. *:*:. ** .*:.* * ******* **: :**:.*:..***** : *:::*:*.* * ** ..:*:.*:**:* *********.**** **: ** *.***.::*.. *:*:::*.***:*:************:*.** : . ::**. . : .*.: :*:*.::** :...**::: *** **.::.:*:*******::*:", "identical_positions": 214, "similar_positions": 112, "identity": "53.77%" }, { "cls_id": "homologset.agr.RGD:620593", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54814-1", "uniprot_id": "CCR3_RAT", "id": "O54814-1", "name": "C-C chemokine receptor type 3", "aln": "MASNEEELKTVVETFETTPYEYEWAPPCEKVSIRELGSWLLPPLYSLVFIVGLLGNMMVVLILIKYRKLQIMTNIYLLNLAISDLLFLFTVPFWIHYVLWNEWGFGHCMCKMLSGLYYLALYSEIFFIILLTIDRYLAIVHAVLALRARTVTFATITSIITWGFAVLAALPEFIFHESQDNFGDLSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIQLIFVVMIVFFIFWTPYNLVLLLSAFHSTFLETSCQQSIHLDLAMQVTEVITHTHCCINPIIYAFVGERFRKHLRLFFHRNVAIYLRKYISFLPGEKLERTSSVSPSTGEQEISVVF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51678-1", "uniprot_id": "CCR3_MOUSE", "id": "P51678-1", "name": "Probable C-C chemokine receptor type 3", "aln": "MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51677-1", "uniprot_id": "CCR3_HUMAN", "id": "P51677-1", "name": "C-C chemokine receptor type 3", "aln": "MTTSLD----TVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . : .**:* **.* : . ***. : * : ::******** :*****::**:******:*:*******:**********.*:******* ::* *** ***:***:*: .***********************:*********..****:***:* *********:*::: * : **. ***. **::**:***.** *.****:*.***:**********.***:***:****:* **********:.:*:*:::* :: ..*::* ****.* *****:::***:**:***********:** ****:: ::* :**.***.**:**********.* *:*:**", "identical_positions": 234, "similar_positions": 83, "identity": "65.18%" }, { "cls_id": "homologset.agr.RGD:620594", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LCA0-1", "uniprot_id": "A0ABK0LCA0_RAT", "id": "A0ABK0LCA0-1", "name": "", "aln": "MGMLGAELGSLRAQPHKGEGRIGMSQCHRKSPFKAPVLLLGSWHFFTDCPQDHFQKSKAAPSFLLASSAATQNLWIPEMNATDVTDTTQDEAAYNSYYFDESLPKPCTKEGIKAFGEVFLPPLYSLVFLLGLFGNSVVVLVLFKYKRLKSMTDVYLLNLAISDLLFVLSLPFWGYYAADQWVFGLGLCKIISWMYLVGFYSGIFFIMLMSIDRYLAIVHAVFSLRARTLTYGVITSLITWSVAVFASLPGLLFSTCDTENNHTYCKTQYSVNSTTWKVLSSLEINVLGLVIPLGIMLFCYSMIIRTLRHCKNEKKNRAVRMIFAVVVLFLGFWTPYNVVLFLETLVELEVLQDCTLERYLDYAIQATETLAFIHCCLNPVIYFFLGEKFRKYIAQLFRTCRGPLVLCQHCDFLQISSADTSSSSYTQSTVDHDFRDAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51680-1", "uniprot_id": "CCR4_MOUSE", "id": "P51680-1", "name": "C-C chemokine receptor type 4", "aln": "------------------------------------------------------------------------------MNATEVTDTTQDETVYNSYYFYESMPKPCTKEGIKAFGEVFLPPLYSLVFLLGLFGNSVVVLVLFKYKRLKSMTDVYLLNLAISDLLFVLSLPFWGYYAADQWVFGLGLCKIVSWMYLVGFYSGIFFIMLMSIDRYLAIVHAVFSLKARTLTYGVITSLITWSVAVFASLPGLLFSTCYTEHNHTYCKTQYSVNSTTWKVLSSLEINVLGLLIPLGIMLFCYSMIIRTLQHCKNEKKNRAVRMIFAVVVLFLGFWTPYNVVLFLETLVELEVLQDCTLERYLDYAIQATETLAFIHCCLNPVIYFFLGEKFRKYITQLFRTCRGPLVLCKHCDFLQVYSADMSSSSYTQSTVDHDFRDAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51679-1", "uniprot_id": "CCR4_HUMAN", "id": "P51679-1", "name": "C-C chemokine receptor type 4", "aln": "------------------------------------------------------------------------------MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTCYTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLHDAL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.*:::*** **: *..**: **:**************:**********::**:***************:******************:*********************::**************:******************:************ ************:***** **.*******:**:**************:***:*****************:********:**:*****************:*****************:****************:******:************* ***:**** :***::*.:**: *** .********:***::***", "identical_positions": 308, "similar_positions": 43, "identity": "70.32%" }, { "cls_id": "homologset.agr.RGD:620595", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9G6-1", "uniprot_id": "G3V9G6_RAT", "id": "G3V9G6-1", "name": "", "aln": "MCLLSQEAVTFRDVAVVFSKEEMGLLDAAQRKLYHDVMLENLRNLLAVGG----------QSPNKMKTVDATGIRCLLLG-----------------QLLYWEITGHDANKLARAPEAVVNTQGKGSHFLEQGHSSCHREAEEPPRASEDDSSLDSLTRDHSSTTENQEFLSGRAQGSWCKTHLRKRQ----------------------------NHQKHCLQTLMK----------NKPELLTQHSPVQRTQEDSRHS----------SSVPIQQSVHPGRKRYWCHECGKGFSQSSALQTHRRVHTGEKPCRDNSCRKSFSRSSGLSIHRQVHTGERPYRCKVCGKGFLRWSHLQAHERIHTGEKPYKCGECGKRFSCISNLHTHQRFHSKEKPYKCDKCGKCFSLNFNLHIHQRVHTGEKPYKCEECGKCFSLSFNLHSHQRVHTGEKPYKCEECGKCFSSASSFQRHRQIHIKEKTLHRDVCGKGSSRDSNLQTHQRVHIQEKPYRCNSCGKSFRCSMDLNIHRRVHTGEKPYKCEVCGKGFNYLSHLQAHEKIHADQKPYKCEYCGRRFSYSSNLHTHQRVHTGEKPYKCEECGKSFSLASSLQAHQRVQTGKKPFKCNACQKRFSQAWNLQAHQRVHTGEKPYKCDTCGKAFGQRSSLQIHQRIHTGEKPFKCEECGKEFSLNSGLTAHRRVHTGEKPYECTECGKGFSLASSLRTHQRIHTGEKPFQCNECQKRFSQVSHLQSHQRVHTGEKPYKCDTCGKAFSQKSGLQVHRRIHTGEKPFKCEECGKEFIWSSGLSAHRRVHTGEKTLHG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NYT6-1", "uniprot_id": "ZN226_HUMAN", "id": "Q9NYT6-1", "name": "Zinc finger protein 226", "aln": "-MNMFKEAVTFKDVAVAFTEEELGLLGPAQRKLYRDVMVENFRNLLSVGHPPFKQDVSPIERNEQLWIMTTATRRQGNLGEKNQSKLITVQDRESEEELSCWQIWQQIANDLTRCQDSMINN----SQCHKQGDFPYQVGTELSIQISEDENYIVN-KADGPNNTGNPEFPILRTQDSWRKTFLTESQRLNRDQQISIKNKLCQCKKGVDPIGWISHHDGHRVHKSEKSYRPNDYEKDNMKILTFDHNSMIHTGQKSYQCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQKVHVGEK-LKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIHVGDKSYKSNRGGKNIREST---------QEKKSIK-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*****:****.*::**:***..******:***:**:****:** : ::: : :: * ** :* *:* : **.*:*. ::::*. *: :**. . : :* . : ***:. : . . * ...* * ** *:*.** **.* : * :*: * ::. * * * :*..: :* :.* :. **. ::*.::.*.* * * ****. *..* .*::**.*** : :.* *.**:.: *. *::**. *:**:** ***** * * *:.* ::**.****:* ***: ** *:*: ***:*: ***:*** ***.** * :*: ****************** * * **: ****************** ** .**:* *: :* **: ***** : .****:***** ****:**.****** . . ::* ***********:*****. *:** *:* *: :**:*** **: *. **.*: ** :**************.** :.*: * *::**:**::*: * * * ** ** ******:****:**: ***:**: : ** **::***:**:**:**** *. . .* *:*********:* **** ** ****: ** :******::*: * * **: *:****************: ***:** :*.* **:***.*:*.:*.:. **:: *: :*::: ", "identical_positions": 389, "similar_positions": 187, "identity": "47.44%" }, { "cls_id": "homologset.agr.RGD:620596", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08556-1", "uniprot_id": "CCR5_RAT", "id": "O08556-1", "name": "C-C chemokine receptor type 5", "aln": "MDFQGSIPTYIYDIDYSMSAPCQKVNVKQIAAQLLPPLYSLVFIFGFVGNMMVFLILISCKKLKSMTDIYLFNLAISDLLFLLTLPFWAHYAANEWVFGNIMCKLFTGIYHIGYFGGIFFIILLTIDRYLAIVHAVFAIKARTVNFGVITSVVTWVVAVFVSLPEIIFMRSQKEGSHYTCSPHFLHIQYRFWKHFQTLKMVILSLILPLLVMVICYSGILNTLFRCRNEKKRHRAVRLIFAIMIVYFLFWTPYNIVLLLTTFQEYFGLNNCSSSNRLDQAMQVTETLGMTHCCLNPVIYAFVGEKFRNYLSVFFRKHIVKRFCKHCSIFQQVNPDRVSSVYTRSTGEQEVSTGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51682-1", "uniprot_id": "CCR5_MOUSE", "id": "P51682-1", "name": "C-C chemokine receptor type 5", "aln": "MDFQGSVPTYSYDIDYGMSAPCQKINVKQIAAQLLPPLYSLVFIFGFVGNMMVFLILISCKKLKSVTDIYLLNLAISDLLFLLTLPFWAHYAANEWVFGNIMCKVFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKVRTVNFGVITSVVTWAVAVFASLPEIIFTRSQKEGFHYTCSPHFPHTQYHFWKSFQTLKMVILSLILPLLVMVICYSGILHTLFRCRNEKKRHRAVRLIFAIMIVYFLFWTPYNIVLLLTTFQEFFGLNNCSSSNRLDQAMQATETLGMTHCCLNPVIYAFVGEKFRSYLSVFFRKHMVKRFCKRCSIFQQDNPDRASSVYTRSTGEHEVSTGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51681-1", "uniprot_id": "CCR5_HUMAN", "id": "P51681-1", "name": "C-C chemokine receptor type 5", "aln": "MDYQVSSP--IYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* * * ***:* * ****:*******:******************:*:****.**:***:*****:*******:****:******** :* *** **:::**:*.**:*.***************:******:*.***.***:***:**.****.*** *** ****** *****.** : **:*** *****:***.*:**************:**:****************:*********:********.****:*****************.**********:**:**********.** ***:**:.***** ****** *:*.**********:*:*.**", "identical_positions": 281, "similar_positions": 52, "identity": "79.38%" }, { "cls_id": "homologset.agr.RGD:620597", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49616-1", "uniprot_id": "UPAR_RAT", "id": "P49616-1", "name": "Urokinase plasminogen activator surface receptor", "aln": "MGLLRRRLLLLVVVVTTCVPASQGLRCIQCESNQDCLVEECALGQDLCRTTVLREWEDAEELEVVTRGCAHKEKTNRTMSYRMGSVIVSLTETVCATNLCNRPRPGARGRPFPRGRYLECASCTSLDQSCERGREQSLQCRYPTEHCIEVVT---LQSTERSVKDEPYTKGCGSLPGCPGTAGFHSNQTFHFLKCCNFTQCNGGPVLDLQSLPPNGFQCYSCEGNSTFGCSYEETSLIDCRGPMNQCLEATGLDVLGNRSYTVRGCATASWCQGSHVADSFQTHVNLSISCCNGSGCNRP-------TGGAPGPGPAHLILIASLLLTLRLWG-IPLWT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35456-1", "uniprot_id": "UPAR_MOUSE", "id": "P35456-1", "name": "Urokinase plasminogen activator surface receptor", "aln": "MGLPRR-LLLLLLLATTCVPASQGLQCMQCESNQSCLVEECALGQDLCRTTVLREWQDDRELEVVTRGCAHSEKTNRTMSYRMGSMIISLTETVCATNLCNRPRPGARGRAFPQGRYLECASCTSLDQSCERGREQSLQCRYPTEHCIEVVT---LQSTERSLKDEDYTRGCGSLPGCPGTAGFHSNQTFHFLKCCNYTHCNGGPVLDLQSFPPNGFQCYSCEGNNTLGCSSEEASLINCRGPMNQCLVATGLDVLGNRSYTVRGCATASWCQGSHVADSFPTHLNVSVSCCHGSGCNSP-------TGGAPRPGPAQLSLIASLLLTLGLWG-VLLWT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03405-1", "uniprot_id": "UPAR_HUMAN", "id": "Q03405-1", "name": "Urokinase plasminogen activator surface receptor", "aln": "MG--HPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSG-RAVTYSRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMN-HIDVSCCTKSGCNHPDLDVQYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLWT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PCV3-1", "uniprot_id": "A0A8M9PCV3_DANRE", "id": "A0A8M9PCV3-1", "name": "", "aln": "-----MDLQVSVLLLFVTFTSGHSLSCYQCDD-----------LMGLCRFQTERTCPSG-----------LSKCESVTVVRQLGTTSFTVKAKACS------------------------ADCASGTMNFGISQMSS--------------------------------------------------------TCCNSDQCNKKDAPVPSTGTPNGKMCYYCDENNCFNALS-------YSGREDHCITATG--TFAGESVIVKGCASKSICDGKKMG------AFKNFSCCSGNLCNGA-----------KSVTQSFLFLCFPLIAFILML-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::: . ..:. .* * **. .*** * . .: . *: : * ::. .*. .* * . .: .* .*** :** .. . ** ** *. *. .. * ::*: *** ..* *:***: * *: ::. ..*** . ** . : * * .*: : ", "identical_positions": 46, "similar_positions": 55, "identity": "13.57%" }, { "cls_id": "homologset.agr.RGD:620598", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CIZ9-1", "uniprot_id": "NOX1_MOUSE", "id": "Q8CIZ9-1", "name": "NADPH oxidase 1", "aln": "MAGELRGSRGPLQRIQIAPREAPNLHLTMGNWLVNHWLSVLFLVSWLGLNIFLFVYAFLNYEKSDKYYYTREILGTALALARASALCLNFNSMMILIPVCRNLLSFLRGTCSFCNRTLRKPLDHNLTFHKLVAYMICIFTVIHIIAHLFN-FERYRRSQQAMDGSLASVLSSLSHP-EKED-SWLNPIQSPNMTVMYAAFTSIAGLTGVIATVALVLMVTSAMEFIRRNY---FELFWYTHHLFIVYIICLGIHGLGGIVRGQTEESLGESHPHNCSHSFHEWDDHKGSCRHPHFAGHPPESWKWILAPIAFYIFERILRFYRSQQKVVITKVVMHPSNVLELQMRKRGFSMEVGQYIFVNCPSISFLEWHPFTLTSAPEEEFFSVHIRAAGDWTRNLIRTFEQQHSPMPRIEVDGPFGTVSEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQRADNKLKTQKIYFYWICRETGAFAWFNNLLNSLEQEMEELGKMDFLNYRLFLTGWDSN--IAGHAALNFDRATD--ILTGLKQKTSFGR---------PMWDNEFSRIATAHP-----KSAVGVFLCGPRTLAKSLRKRCQRYSS------------LDPRKVQFYFNKETF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WV87-1", "uniprot_id": "NOX1_RAT", "id": "Q9WV87-1", "name": "NADPH oxidase 1", "aln": "----------------------------MGNWLVNHWLSVLFLVSWLGLNIFLFVYVFLNYEKSDKYYYTREILGTALALARASALCLNFNSMVILIPVCRNLLSFLRGTCSFCNHTLRKPLDHNLTFHKLVAYMICIFTAIHIIAHLFN-FERYSRSQQAMDGSLASVLSSLFHP-EKED-SWLNPIQSPNVTVMYAAFTSIAGLTGVVATVALVLMVTSAMEFIRRNY---FELFWYTHHLFIIYIICLGIHGLGGIVRGQTEESMSESHPRNCSYSFHEWDKYERSCRSPHFVGQPPESWKWILAPIAFYIFERILRFYRSRQKVVITKVVMHPCKVLELQMRKRGFTMGIGQYIFVNCPSISFLEWHPFTLTSAPEEEFFSIHIRAAGDWTENLIRTFEQQHSPMPRIEVDGPFGTVSEDVFQYEVAVLVGAGIGVTPFASFLKSIWYKFQRAHNKLKTQKIYFYWICRETGAFAWFNNLLNSLEQEMDELGKPDFLNYRLFLTGWDSN--IAGHAALNFDRATD--VLTGLKQKTSFGR---------PMWDNEFSRIATAHP-----KSVVGVFLCGPPTLAKSLRKCCRRYSS------------LDPRKVQFYFNKETF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5S8-1", "uniprot_id": "NOX1_HUMAN", "id": "Q9Y5S8-1", "name": "NADPH oxidase 1", "aln": "----------------------------MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFN-FDCYSRSRQATDGSLASILSSLSHD-EKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSY---FEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSN--IVGHAALNFDKATD--IVTGLKQKTSFGR---------PMWDNEFSTIATSHP-----KSVVGVFLCGPRTLAKSLRKCCHRYSS------------LDPRKVQFYFNKENF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12333-1", "uniprot_id": "FRE7_YEAST", "id": "Q12333-1", "name": "Ferric/cupric reductase transmembrane component 7", "aln": "MIEERDLVLSNGIHCIADIHSELYARLKKESQAATPWVYQKQYGKFVTYFVAVIIFLSLIKKLAFMYYDSSEEFLPEKKNSPTTPSVFLARIMTKLVAFNRYICYRKFPTLIFSYLGIPTSVGTFLVVMATTLYTLLYCFVPHPFYRPCAGFGSPPLSVRAGIMAISLVPFVFSLSGKINVIGWLVGLSYEKINIYHQWASILCLFFSWVHVIPFLRQARHEGGYERMHQRWKASDMWRSGVPPILFLNLLWLSSLP-IARRHFYEIFLQLH-WILAVGFYISLFYHVYPELNSHMYLVATIVVWFAQLFYRLAVKGYLRPGRSFMASTIANVSIVGEGCVELIVKDVEMAYSPGQHIFVRTIDKGIISNHPFSIFPSAK---YPGGIKMLIRAQKGFSKRLYESNDDMKKILIDGPYGGIERDIRSFTNVYLICSGSGISTCLPFLQ----KYGPILHKTNLEVITLDWVVRHREDISWIRDEMCTLSNNLRQLFLDGKIVVRIYVCSDSTVPGIIKTFPQTIDTASDQSDLAKREKDTEFGQDDTESNSTFDKSNNEYKGLITIIPSKPDLNQVINDYQIGFRNCFICSGSDSLRYTVGNSVAGLQAKVFSNKNVEECYLHSESFGY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. *. :: : ::: * : : ** : : : . : ::. : . *:.. * : * *. : . :. *.. . * : . * : : * * :* ::: : : : : .** :. : .: : : :. : . : .:.:: . : * . :* : *.:: * : .: *.* : * : : * : .* . . . . *: . : ** ** .*::* : :** :.. :: **:***. . .::. ***:: .:.: :. *: ..: : : :. . : :* :***:* ..*: .: . *: :* *::. .:*: *: :: : : * : *: *. ::*:.: : :*.::: :* . : *::: . .: * . .:* *:* :: ::.*.**: :**:. : * * :..:. : * . . . . **: : . : *::.*.* ", "identical_positions": 78, "similar_positions": 201, "identity": "12.4%" }, { "cls_id": "homologset.agr.RGD:620599", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5T764-1", "uniprot_id": "IFT1B_HUMAN", "id": "Q5T764-1", "name": "Protein IFIT1 homolog B", "aln": "-------------------------MSEESDGKLIEDSLIQLRCHFTWKLLIEAPEIPDLENRIWEEIQFLDTKYNVGIHNLLAYVKHLKGQNEEALVSLKKAEDLIQKEHANQADIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFANPSRYRMECPEVDCEEGWALAKCGGKNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTASGRNKAFSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQMIQIKEATNWQPRGQDRETVDRLVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRMKIFEDQLKQEIHYHYGRFQEHHGKSQDKAITHYLKGLKIEKMSHSREKLLNALEKLAKRCIHQNVRVVESVSLLGLIHKLKGEVSDALLCYERALRLAADLNPIF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09914-1", "uniprot_id": "IFIT1_HUMAN", "id": "P09914-1", "name": "Antiviral innate immune response effector IFIT1", "aln": "-------------------------MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LPS6-1", "uniprot_id": "F1LPS6_RAT", "id": "F1LPS6-1", "name": "", "aln": "MMNRMKHAQEPISYGSEFRVSIYTELRENADGDQVMENLLQLRCHFTWGLLFEKNDIPDLEVRISEQVQFLDIKNSLGMHNLQAYVRHLKGEQEEALQSLKEAEALIEGE---QLGKRSLVTWGNCAWVHYHRGSLAEAQIYLDKVENVCREFSSPFHYRMECAEIDCEEGWALLKCGGSNYMRAMACFAKALQVDPENPEYNAGYAVVAYRQD------FDDNHVSLEPLRKAVRLNPEDPHLKVLLALKLQDLGEQDEAETHIEEALSSTSCQSYVFRYAAKYFRRKGDINEALHLLHRALQTSPSSGYLHYQKGLCYKQQMIQLKTSGNRQARRQ--ENIQELAHQAICEFQETLNLRPTFEMAYVCMAEMQAEIGQYEEAEGNFQEALNLNNLVAHIEQDIHFRYGRFQQFHKKSEDKAITHYLKGLKLEEKSFAWRKLLTALEKVAERRVRQNVRLVESTSLLGLVFKLKGQEMKALLYYEKALRLSGEMNPAF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64282-1", "uniprot_id": "IFIT1_MOUSE", "id": "Q64282-1", "name": "Antiviral innate immune response effector IFIT1", "aln": "-------------------------MGENADGDQVMENLLQLRCHFTWKLLFENNDIPDLEVRISEQVQFLDIKNPLGMHNLLAYVRHLKGQQDEALQSLKEAEALIQSE---QLSKRSLATWGNCAWLHYHRGSLAEAQIYLDKVEKVCKEFSSPFRYRLECAEMDCEEGWALLKCGGGNYKQAMACFAKALKVEPENPEYNTGYAVVAYRQD------LDDNFISLEPLRKAVRLNPEDPYLKVLLALKLQDLGEHVEAEAHIEEALSSTSCQSYVIRYAAKYFRRKHRVDKALHLLNRALQASPSSGYLHYQKGLCYKQQISQLRTSRNRQPRRQ--DNVQELAQQAIHEFQETLKLRPTFEMAYVCMAEVQAEIHQYEEAERNFQKALNNKTLVAHIEQDIHLRYGRFLQFHKQSEDKAITLYLKGLKVEEKSFAWRKLLTALEKVAERRVCQNVHLVESTSLLGLVYKLKGQEKNALFYYEKALRLTGEMNPAF----", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.*.. : :.* ******** * :: ::**** *: ::::*** * :*:*** ***:****:::*** ***:** *:: * * . ***.**** **::** * ***** ******: *::::.* :**:**.*:******** **** ** :* :** *.*: :***** .:***: .** * .: .** *::******:: :::********* *:. *.* :*****:. *.*:**::****::*** :::**.**: **: :*:* **:* ****: *: *:: : : *.* * :.::.: : ** .*:.:: : ***:*:: :*. * ::.:** :**: * : . . *:** :**** :.: :*: :** ***.:*:*: * : * :.:*:*:. * : ::. :** ****::.**:*: .** **:****:.::: . ", "identical_positions": 210, "similar_positions": 151, "identity": "41.75%" }, { "cls_id": "homologset.agr.RGD:62060", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15294-1", "uniprot_id": "OGT1_HUMAN", "id": "O15294-1", "name": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit", "aln": "MASSVGNVADSTEPTKRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTALNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIKPVEVTESA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CGY8-1", "uniprot_id": "OGT1_MOUSE", "id": "Q8CGY8-1", "name": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit", "aln": "MASSVGNVADSTEPTKRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVAEQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNPDSSNTALNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKSRQEYEDIAVKLGTDLEYLKKIRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIKPVEVTESA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56558-1", "uniprot_id": "OGT1_RAT", "id": "P56558-1", "name": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit", "aln": "MASSVGNVADSTG----------LAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVAEQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADTTNTALNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMGANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKSRQEYEDIAVKLGTDLEYLKKIRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIKPVEVTESA", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************ ***************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************************:*****************************************************************************************************************************************************************************************************************************************************************************.*::******************************************************************************************** **************************************************************************************************************.********************:*****************************************************", "identical_positions": 1028, "similar_positions": 6, "identity": "98.28%" }, { "cls_id": "homologset.agr.RGD:620600", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHI8-1", "uniprot_id": "NOX4_MOUSE", "id": "Q9JHI8-1", "name": "NADPH oxidase 4", "aln": "----------------------------------------------MAVSWRSWLANEGVKHLCLLIWLSLN----------VLLFWKTFLLYNQ------------GPEYYYIHQ---------------------------------------------MLGLGLCLSRASASVLNLNCSLILLP---------------MCRTVLAYLRGSQKVPSRRTRRLLDKSKTLHITCG----VTICIFSGVHVAAHLVNALN------------FSVNYSEDFLELNAARYQNEDPRKLLFTTIPGLTGVCMVVVLFLMVTASTYAIRVSN---------YDIFWYTHNLFFVFYMLLLLHVSGGLLKYQTNVDTHPPGCISLNQTSSQNMSIPDY----VSEHFHGSLPRGFSKLEDRYQKTLVKICLEEPKFQAHFPQTW-IWISGPL-CLYCAERLYRCIRSNKP-VTIISVINHPSDVMELRMIKEN--FKARPGQYIILHCP-SVSALENHPFTLTMCPTETKATFGVHFKVVGDWTERFRDLLLPPSSQDSEILPFI-HSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVT-PFASILNTLLDDWKPYKLRRLYFIWVCRDIQSFQWFADLLCVLHNK------FWQENRPDFVNIQLYLSQTDGIQKIIGEKYHTLNSRLFIGRPRWKLLFDEIAKCNRGKTVGVFCCGPS-SISKTLHSLSNRNNSYGTKFEYNKESFS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924V1-1", "uniprot_id": "NOX4_RAT", "id": "Q924V1-1", "name": "NADPH oxidase 4", "aln": "----------------------------------------------MALSWRSWLANEGVKHLCLLVWLSLN----------VLLFWKTFLLYNQ------------GPEYYYIHQ---------------------------------------------MLGLGLCLSRASASVLNLNCSLILLP---------------MCRTVLAYLRGSQKVPSRRTRRLLDKSKTLHITCG----ITICIFSGVHVAAHLVNALN------------FSVNYSEHFLALNAARYQNEDPRKLLFTTVPGLTGVCMVVVLFLMVTASTYAIRVSN---------YDIFWYTHNLFFVFYMLLLLHVSGGLLKYQTNLDTHPPGCISLNRTPSQNMSIADY----VSEHFHGSLPGGFSKLEDHYQKTLVKICLEEPKFQAHFPQTW-IWISGPL-CLYCAERLYRCIRSNKP-VTIISVINHPSDVMELRMIKEN--FKARPGQYIILHCP-SVSALENHPFTLTMCPTETKATFGVHFKVVGDWTERFRDLLLPPSSQDSEILPFI-QSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVT-PFASILNTLLDDWKPYKLRRLYFIWVCRDIQSFQWFADLLYVLHNK------FWQENRPDFVNIQLYLSQTDGIQKIIGEKYHTLNSRLFIGRPRWKLLFDEIAKCNRGKTVGVFCCGPS-SISKTLHNLSNRNNSYGTKFEYNKESFS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NPH5-1", "uniprot_id": "NOX4_HUMAN", "id": "Q9NPH5-1", "name": "NADPH oxidase 4", "aln": "----------------------------------------------MAVSWRSWLANEGVKHLCLFIWLSMN----------VLLFWKTFLLYNQ------------GPEYHYLHQ---------------------------------------------MLGLGLCLSRASASVLNLNCSLILLP---------------MCRTLLAYLRGSQKVPSRRTRRLLDKSRTFHITCG----VTICIFSGVHVAAHLVNALN------------FSVNYSEDFVELNAARYRDEDPRKLLFTTVPGLTGVCMVVVLFLMITASTYAIRVSN---------YDIFWYTHNLFFVFYMLLTLHVSGGLLKYQTNLDTHPPGCISLNRTSSQNISLPEY----FSEHFHEPFPEGFSKPAEFTQHKFVKICMEEPRFQANFPQTW-LWISGPL-CLYCAERLYRYIRSNKP-VTIISVMSHPSDVMEIRMVKEN--FKARPGQYITLHCP-SVSALENHPFTLTMCPTETKATFGVHLKIVGDWTERFRDLLLPPSSQDSEILPFI-QSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVT-PFASILNTLLDDWKPYKLRRLYFIWVCRDIQSFRWFADLLCMLHNK------FWQENRPDYVNIQLYLSQTDGIQKIIGEKYHALNSRLFIGRPRWKLLFDEIAKYNRGKTVGVFCCGPN-SLSKTLHKLSNQNNSYGTRFEYNKESFS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08908-1", "uniprot_id": "FRE5_YEAST", "id": "Q08908-1", "name": "Ferric reductase transmembrane component 5", "aln": "MLFARLVLLLVYLAPGSLAKPASTKKRTQWDQIAIDACAKELESHKFDTDVKGRHATLCTYEPALGSWLHCAKDVLDSRKKSKKIFEKTFSKINQYCHDYHKDEVVSNEEYYRIFANASLFIRPLDEVKENIRYPVTPNKASLDRWVWAYFGPLDNIDKGNVYGVTICLYWIGVLFIAAVYHFLNFSR---------LKQTVFKNKVSAFLRGHYVLPALVHNHAMSVGRWFFIGLVPTRLETLVLFGYVLLHGFLLSSYN------------FDHNELLSDRRSQVLIFLSDRAGILAFAHFP-------LIVLFGGKNSTMTWLTGIR---------YTAFITYHKWLGRFMLVDCTIHAIGYTYHAYIENYWKYVKYSDLWTSGRHAMIIVG----ILVFFSFFFFRRHYYELFVITHIILAIGFFHACWKHCYKLGWGEWIMACA-LFWIADRILRLIKIAIFGMPWAKLKLCGESMIEVRISKSSKWWKAEPGQYIYLYFLRPKIFWQSHPFTVMDSLVE-DGELVVVITVKNGLTKKLQEYLLES------------EGYTEMRVLAEGPYGQSTRTHL-FESLLFIAGGAGVPGPLSMAIKAGRQVKSNDSHQMIKFVWSVRNLDLLEVYRKEIMVLKELNIDTKIYFTGERKDESNTEEGAIANMSTEGRLLTTSKSAEMITDFGRPNIDEIIEEAVSG--AKSLLVTCCGSEGFVDKTRELTAKRVLEHGDKWIEYVEEFQNW", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12209-1", "uniprot_id": "FRE8_YEAST", "id": "Q12209-1", "name": "Probable ferric reductase transmembrane component 8", "aln": "---MNLKSIVSWFKEHLPSFDVDVDKHFRTLRVRKYSQICLLISFIIICVIIPLMNYLLLTDKFFKICHHLKHHVFNR----RSWVHKTHMYHKQS--LQLCLICFVFTSFFVIQG-----------------------------------------ANGDLLEITKRMGRISVALMPPLLFLTLRPSPLPHT--LYLALLPLHKWISRIVVLESILHTWFYLYYMYINDTLYVKMR----KLPNIYGVIALGLFLLIAITSVRYARRWSYRVFYYVHYVSTWLILVFLHYHARPGISYYTTLNVLILTGQIVYRLHITNVTRVTIVPISSSLSLLEFPLTDLPKKPILPGGHLRINIYHRNFLRRFFSHLIPFQHPFTIASIPSDNLVRLIIRNGHFPLRTNEKYYITGAFEPELSFISKPTVPFNITTKSSKNPFRNNSSALINSPLNFLIKAQRVFMCVGGSGISFGLPLLRILNFNGVNVRLLWVS---RDYKDLEVLNHFKNNFEGMEIYISGTEGNEQDIEIDYIDYHDCAADINDEVRSISSSGRVSELGDNSMLSDGNPQPTEPNENTALLSKKSTLRNHHPPKTSDIPDINADDEIDFTYAFSRSKSRKNTAQGTLTTHSSFNGSSVFRQPKIIEPPAQDPCLEAAPKKIRIPAGVKVFFGRPTLGDKDYEWCLQTECDAETDSIQCCRWANQGRDHAEYLSQVWVLAAGPRGLIESTKRWATDG------GLHFHGESFAL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53109-1", "uniprot_id": "AIM14_YEAST", "id": "P53109-1", "name": "Probable metalloreductase AIM14", "aln": "---MKESPLITLVKRHSETHFANIKYGYYVLIISLVYLIGLALLRAFGRRTPSRSSSAFKNKIIYRLYDIDP------------AIHLGILFFAV------------LIPFYYHYS-----------------------------------------LTTQSTVYLKRLGRLSYALIPLNLFLTLRPNWFLRKNCTYTDFIPFHKWFSRIITVIGLLHGIFFIIKWAIDDNVSLKQK-LILKTFNFAGFIISILVLFLLICSIGPMRRYNYRLFYIVHNLVNVAFILLTPIHSRPG---------------VKFPFLLLNCTLLFIHIIN---------RIVFAKSLMILNKNANYSKTNLVHVRLPRAILPDYFEPGSHIRISPYR-------------RINPLYWLLPSHPYTIASLAEDNSIDLIIKETSTAEPGSQIESLRSNPKSFHLDQEKTYTLIN----SYPPSVPEECYSQGTNIAIICGGSGISFALPLFRHFFNKENVKYLKMIWLIKDYSEYELVLDYLKTN-------------------------------------------GLTFEKKLSNNKRISVFISGEYTAETRLDEITTNIDDENSEYEMGSFNNEDEDLSISNFNSE----------------------NADSNDNTPETSHSPTKENGSMIEVKSKHSFTLSNELKSFNNESAQVNQNETWLFSCGPPSLLQLSKKYCNDE------RINFVCETYGL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . :. : . .: : . : . . : : . . : : . : *. * . : : . : : : . : . . : :: : . :: : . . : : . . * . . . .:. . . : : . : ..*. :. : . . * : ", "identical_positions": 5, "similar_positions": 69, "identity": "0.66%" }, { "cls_id": "homologset.agr.RGD:620601", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89039-1", "uniprot_id": "ACKR3_RAT", "id": "O89039-1", "name": "Atypical chemokine receptor 3", "aln": "----------------MDVHLFDYVEPGN---------------YSDINWPCNSSDCIVVDTVQCPAMPNKNVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVITIPVWVVSLVQHNQWPMGELTCKITHLIFSINLFGSIFFLACMSVDRYLSITYFTSTSSYKKKMVRRVVCVLVWLLAFFVSLPDTYYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVILGFAVPFTIIAIFYFLLARAMSAS-------GDQEKHSSRKIIFSYVVVFLVCWLPYHFVVLLDIFSILHYIPFTCQLENVLFTALHVTQCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQNTK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56485-1", "uniprot_id": "ACKR3_MOUSE", "id": "P56485-1", "name": "Atypical chemokine receptor 3", "aln": "----------------MDVHLFDYAEPGN---------------YSDINWPCNSSDCIVVDTVQCPTMPNKNVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVITIPVWVVSLVQHNQWPMGELTCKITHLIFSINLFGSIFFLACMSVDRYLSITYFTGTSSYKKKMVRRVVCILVWLLAFFVSLPDTYYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVILGFAVPFTIIAIFYFLLARAMSAS-------GDQEKHSSRKIIFSYVVVFLVCWLPYHFVVLLDIFSILHYIPFTCQLENVLFTALHVTQCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQNTK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25106-1", "uniprot_id": "ACKR3_HUMAN", "id": "P25106-1", "name": "Atypical chemokine receptor 3", "aln": "----------------MDLHLFDYSEPGN---------------FSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISAS-------SDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEZ8-1", "uniprot_id": "A0A8M2BEZ8_DANRE", "id": "A0A8M2BEZ8-1", "name": "", "aln": "MRTKPWINIAHSTSIKGKMTEIQSSSPNEKLGLSASELTEFFAMWEELNFTDSNNNSSRVEAQMCPASFNRSALLNAMCTLYAFIFVVGLAANALVVWVNMRSQRHYHETHMYILNLAVADLCVVATLPVWVSSLAQGGHWAFGQAACKLTHLLFSVNLFASIFFLTCMSVDRYLSVVRFREISHRRGRQVRRLVCAITWLLALFASVPDTYFLRSVKSQYSHVTLCLPVYPEDNPLQWMVGIQLSFVVLGFAIPFPIIAVSYALLANTLASTSTHSPSNGDQDRSVSKKVILMYIVVFIACWAPYHAVLLADALAMLGVLPLGCSSENGLFVALHLTQCLSLLHCCVNPVVYSFAHRHYRYDLMKAFIFKYSTRTGLARLIDGSQGIETEYAMVENNPPTVT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :: .*.: :.::.:. ...:. *:: ** *:..** ::. :* ****:*: **::*****:::: ::** ******:*** ** *:**** **.* .:*.:*: :**:***:**:***.*****:*********:. * . : : ***:** :.****: .*:****:*::*.* .: * * ..***.. :*::*::* *:****:**.***: * ***.::::: .**:: *:*:*: *:***:.** *** .:* * :::* :*: * *: **.***:******:*******:*** :*:***:**********::***::***.*: ****: :*:.. ", "identical_positions": 174, "similar_positions": 123, "identity": "43.18%" }, { "cls_id": "homologset.agr.RGD:620603", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W509-1", "uniprot_id": "Q9W509_DROME", "id": "Q9W509-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------MVHG---PPARRKSQQQ-------HEACEMDMERQP--------------------------------------TPPDGGWG-WVVVFGSFMIHIVTDGMTYSFGIFYNEFLD---YFNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGN-------YGWRGAMLIIGGIVLNCIIFG--AMFRPL----------------------------------------ELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLP---------------------KDQYLQLPQRTDTAVSGGALCRS----NSVGHNLKPNLNNNSN----------GAVNGQGPTLVT------------PPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRE----RSASGTMYRP----DALYQGSLHNLPDYVSS------RNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVN--RLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWM---YDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERKPHTEHLALS---------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0L6-1", "uniprot_id": "Q9W0L6_DROME", "id": "Q9W0L6-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDD---------------DEESVYGELPPPPDGGYG-WVICFASFMCNMIVDGIAYTFGIFLEEFVA---YFHEGKGTVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEE-------YGWKNALLIFAGLILNCAIFG--AMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADLPQVN--SLLLNNCCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLAGAI---YDMTHTYDLPFYMAGALFGISTITSFLAPCLKRCSPSE-ETPVHVETLTPIDEEQGEDAEDDEDQPIT----------------------------IVPKIIKTLASPQQEEGHPQFPQKTSESKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P57787-1", "uniprot_id": "MOT4_MOUSE", "id": "P57787-1", "name": "Monocarboxylate transporter 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MGGAVVDEGPTG-------------------------------------IKAPDGGWG-WAVLFGCFIITGFSYAFPKAVSVFFKELMH---EFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQPSLIMLNRYFNKRRPIANGLAAAGSPVFLCALSPLGQLLQDH-------YGWRGGFLILGGLLLNCCVCA--ALMRPLVA-----------------------------------------------------------------------------------------------------------PQVGGGTEPRGPQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RPPQRLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLKKVRPYSVYLFSFAMFFNGFTDLTGSTATDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKL---LDATKVYKYVFILAGAEVLTSSLVLLLGNFFCIG-KRKRPEVTEPEEVASEE-KLHKPPVDVGVDS------------------------------REVEHFLKAEPEKNGE-----VVHTPETSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35910-1", "uniprot_id": "MOT4_RAT", "id": "O35910-1", "name": "Monocarboxylate transporter 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MGGAVVDEGPTG-------------------------------------IKAPDGGWG-WAVLFGCFIITGFSYAFPKAVSVFFKELMH---EFGIGYSDTAWISSILLAMLYGTGPLCSMCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQPSLIMLNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQDH-------YGWRGGFLILGGLLLNCCVCA--ALMRPLVA-----------------------------------------------------------------------------------------------------------PQASGGAEPHGPQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RPSPRLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLKKVRPYSVYLFSFAMFFNGFTDLTGSTASDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKL---LDATKVYKYVFILAGAEVLTSSLVLLLGNFFCIG-KRKRPEVTKPEEVASEEEKLHKPPVDVRVDS------------------------------REVEHFLKAEPEKNGE-----VVHTPETSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15427-1", "uniprot_id": "MOT4_HUMAN", "id": "O15427-1", "name": "Monocarboxylate transporter 4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MGGAVVDEGPTG-------------------------------------VKAPDGGWG-WAVLFGCFVITGFSYAFPKAVSVFFKELIQ---EFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDR-------YGWRGGFLILGGLLLNCCVCA--ALMRPLVV-----------------------------------------------------------------------------------------------------------TAQPG----SGPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKL---LDATHVYMYVFILAGAEVLTSSLILLLGNFFCI---RKKPKEPQPEVAAAEEEKLHKPPADSGVDL------------------------------REVEHFLKAEPEKNGE-----VVHTPETSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q7T3-1", "uniprot_id": "F1Q7T3_DANRE", "id": "F1Q7T3-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MGGAVVDTGDSG-------------------------------------VKAPDGGWG-WAVLFGCFIITGFSYAFPKAVSVFFKELIR---EFGVGYSDTAWISSILLAMLYGTGPLCSILVNRFGCRPVMMVGGLFASLGMVLASFATNIIHIYLCTGVITGLGLALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYK-------YGWRGGFLILGGLLLNCCACG--ALMRPLLA-----------------------------------------------------------------------------------------------------------PKKT--SEVEEKP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KETKPKPKLLDFTVFKDRGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLTILGFIDIFARPTSGIIAGLKWVRPRCVYLFSFAMIFNGIADILGSFAKDYASLVVFCIFFGISYGMVGALQFEVLMAIVGTEKFSSAIGLVLLVEAIAVLVGPPGAGRL---LDATKNYMYVFMLAGCEVVLSALVLAICNLLFIKRKPQQPDPPAKMEMAITETEMEELNKAPKDDQDNGGGAENEKKQAIEPETKTTSKDEVKELESIEVDSIEVENASKKVSGPNGVAVEPESSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BBA0-1", "uniprot_id": "A0A8M2BBA0_DANRE", "id": "A0A8M2BBA0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MGGVALDDGGCK-------------------------------------VKAPDGGWG-WAVLFGCFVITGFSYAFPKAVSVFFKELIR---EFGVGYSDTAWISSILLAMLYGTGPLCSILVNRFGCRPVMLVGGLFASLGMILASFATSIIHIYLCTGVITGLGMALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYE-------YGWRGGFLILGGILLNCCACG--ALMRPLVP-----------------------------------------------------------------------------------------------------------PKSSEAPGIENAPDDG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------DKTVKPKPKLLDFSVFRDRGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLSILGFIDIFARPTCGIIAGLQWVRPRCVYLFSFALIFNGITDLVGSLSKDYTSLVVFCIFFGISYGMVGALQFEVLMAVVGTEKFSSAIGLVLMLEAIAVLVGPPSAGRL---LDHTKKYMFVFLLAGIEVVLSALVLAICNFLCIKKKPEAPDAAAVESGEPVEEKNHSSPPATEEPHTPNGNSE-KPKTDLRPE-------NVTEEPTEEETFLKEEDEKEKT-----ITCSAESDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53918-1", "uniprot_id": "ESBP6_YEAST", "id": "P53918-1", "name": "Uncharacterized transporter ESBP6", "aln": "MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYG-WVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSD-------FGNTRWCLRIIGISCSISVLVAIALLK----------------------------------------------------------------------------------------------------------------ERNPTPAIGLKSPR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------AMFEQLKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGDKFGRANVTIVLTTLLTIY---MFAFWIPAHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWG------------------------------KLKERKTKYDLLLGPGIKKYFLRMVYPMKV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36032-1", "uniprot_id": "MCH2_YEAST", "id": "P36032-1", "name": "Probable transporter MCH2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MSEERHEDHHRDVENKLNLNGKDDINGNTSIS-----------------------------------IEVPDGGYG-WFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQK-------RGVKWALIAQCIICTSLSTIA---------------------------------------------------------------------------------------------------------------------LMLTRTTHQGLRQHKR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILH---LVMAILCWAMWIPCKNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNELHLNVKLS--------------------------------------HMSKCLFRYKQLPRRV--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08777-1", "uniprot_id": "MCH5_YEAST", "id": "Q08777-1", "name": "Riboflavin transporter MCH5", "aln": "----------------------------------------------------------------------------MSSDSLTPKDTIVPEEQTNQLRQPDLDEDSIHYDPEADDLESLETTASYASTSVSAKVYTKKEVNKGTDIESQPHWGENTSSTHDSDKEEDSNE-------------------------------EIESFPEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDNQ-LSSESVSTIGWLFSLFLFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLTLSIILVKERLPH----------------------------------------------------------------------------------------------------------VIENSKDGESRWRYILR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYILQCFDAKAFLDMKYLFCVLGTVFSELSINSALTYYGSYATSHGISANDAYTLIMIINVCGIPGRWVPGYLSDKFGRFN--VAIATLLTLFIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFSLLPVCCGQISKTEEFGKRYSTMYFVVGFGTLVGIPITGAIIS-IKTTADYQHYIIFCGLATFVSAVCYIISRAYCVGFKWVRF--------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:**: * : : :: . .: . . : .: : . : * . . : . . .. * . .: * :* :* * .:. * : * : :. : . : . : .. : :. .* * . : : . * . : .:: . . :: : * : * : ", "identical_positions": 17, "similar_positions": 64, "identity": "1.7%" }, { "cls_id": "homologset.agr.RGD:620604", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62005-1", "uniprot_id": "ZP1_MOUSE", "id": "Q62005-1", "name": "Zona pellucida sperm-binding protein 1", "aln": "------MAWGCFVVLLLLAAAPLRLGQRLHLEP---GFEYSYDCGVRGMQLLVFPRPNQTVQFKVLDEFGNRFEVNNCSICYHWVTSEAQEHTVFSADYKGCHVLEK-DGRFHLRVFIQAVLPNGRVDIAQDVTLICPKPDHTVTPDPYLAPPTTPEPFTPHAFALHPIPDHTLAGSGHTGLTTLYPEQSFIHPTPAPPSLGPGPAGSTVPHSQWGTLEPWELTELDSVGTHLPQERCQVASGHIPCMVNGSSKETCQQAGCCYDSTKEEPCYYGNTVTLQCFKSGYFTLVMSQETALTHGVLLDNVHLAYAPNGCPPTQKTSAFVVFHVPLTLCGTAIQVVGEQLIYENQLVSDIDVQKGPQGSITRDSAFRLHVRCIFNASDFLPIQASIFSPQPPAPVTQSGPLRLELRIATDKTFSSYYQGSDYPLVRLLREPVYVEVRLLQRTDPSLVLVLHQCWATPTTSPFEQPQWPILSDGCPFKGDNYRTQVVAADREALPFWSHYQRFTITTFMLLDSSSQNALRGQVYFFCSASACHPLGSDTCSTTCDSGIARRRRSSGHHNITLRALDIVSSPGAVGFED----AAKLEPSGSSRNSSSR---MLLLLL-AITLALAAGIFVGLIWAWAQKLWEGIRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54766-1", "uniprot_id": "ZP1_RAT", "id": "O54766-1", "name": "Zona pellucida sperm-binding protein 1", "aln": "------MAWGCFVVLLLLVAAPLRLGQHLHLKP---GFQYSYDCGVQGMQLLVFPRPNQTIQFKVLDEFGNRFEVNNCSICYHWVISEAQKPAVFSADYKGCHVLEKQDGRFHLRVFIQAVLPNGRVDTAQDVTLICPKPDHILTPESYLAPPTTPQPFIPHTFALHPISGHTLAGSGHTGLTTLYPET---HPTPAPPSSEPGPVGPTVPQSQWGTLGSWELTELDSIGTHLLQERCQVASGHIPCMVKGSSEEACQQAGCCYDNTKEMPCYYGNTVTLQCFRSGYFTLVMSQETALTHGVMLDNVHLAYAPNGCPPTQKTSAFVVFHVPLTLCGTAIQVVGKQLVYENQLVSNIEVQTGPQGSITRDGVFRLHVRCIFNASDFLPIRASIFSPQPPAPVTRSGPLRLELRIATDKTFSSYYQGSDYPLVRLLQEPVYIEVRLLQRTDPGLALMLHQCWATPSASPFEQPQWPILSDGCPFKGDNYRTQMVAADRATLPFWSHYQRFTIATFTLLDSSSQNALRGQVYFFCSASACHPVGSETCSTTCDSEIARHRRSSGHHNSTIRALDIVSSPGAVGFED----APKLEPSGSTRNSGSRPLLWVLQLL-ALTLVLGDGVLVGLSWAWAWA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60852-1", "uniprot_id": "ZP1_HUMAN", "id": "P60852-1", "name": "Zona pellucida sperm-binding protein 1", "aln": "MAGGSATTWGYPVALLLLVAT-LGLGRWLQPDPGLPGLRHSYDCGIKGMQLLVFPRPGQTLRFKVVDEFGNRFDVNNCSICYHWVTSRPQEPAVFSADYRGCHVLEK-DGRFHLRVFMEAVLPNGRVDVAQDATLICPKPDPSRTLDSQLAPPAMFSVSTPQTLSFLPTSGHTSQGSGHAFPSPLDPGHSSVHPTPALPSPGPGPTLATLAQPHWGTLEHWDVNKRDYIGTHLSQEQCQVASGHLPCIVRRTSKEACQQAGCCYDNTREVPCYYGNTATVQCFRDGYFVLVVSQEMALTHRITLANIHLAYAPTSCSPTQHTEAFVVFYFPLTHCGTTMQVAGDQLIYENWLVSGIHIQKGPQGSITRDSTFQLHVRCVFNASDFLPIQASIFPPPSPAPMTQPGPLRLELRIAKDETFSSYYGEDDYPIVRLLREPVHVEVRLLQRTDPNLVLLLHQCWGAPSANPFQQPQWPILSDGCPFKGDSYRTQMVALD-GATPFQSHYQRFTVATFALLDSGSQRALRGLVYLFCSTSACHTSGLETCSTACSTGTTRQRRSSGHRNDTARPQDIVSSPGPVGFEDSYGQEPTLGPTDSNGNSSLRPLLWAVLLLPAVALVLGFGVFVGLSQTWAQKLWESNRQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** *.****.*: * **: *: .* *:.:*****::**********.**::***:*******:*********** *..*: :******:******* *********::********* ***.******** * :. ****: . *::::: * ..** ****: :.* * ***** ** ***. .*:.:.:**** *::.: * :**** **:*******:**:*. :*:*:*********.*:* *******.*:***:.***.**:*** **** : * *:******..*.***:*.*****:.*** ***::**.*.**:*** ***.*.:*.*********..*:*****:*********:****.* .***:*:.**********.*:****** .***:****:***::**********.*.*:*****.:*::.**:****************.****:** * : ** *******::** ****.**.**** **:***:****. * :****:*.: :*:******:* * *. *******.***** ..* *:.*. **. * : ** *::*.*. *::*** :** ", "identical_positions": 395, "similar_positions": 143, "identity": "61.62%" }, { "cls_id": "homologset.agr.RGD:620605", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54767-1", "uniprot_id": "ZP2_RAT", "id": "O54767-1", "name": "Zona pellucida sperm-binding protein 2", "aln": "MARWQR---------------VYWLRSLFFALVTSVNSLSLPQSENPAFPGTLICDKDEVRVEFSSRFDMEKWNPSLVDTFGNEISN-CTYALDLEKFILKFPYETCTIKVIGGYQVNIRVQDTNADVSYKDDVHHFFCPAIQAEIHE--VSEIVVCMEDLISFSFPQLFSRLADENQ---------------------------------------------------------------------------------------NVSEMGWIIKIGN----------------------------------------GTRVHTLPLKDAIVQGFNLLIDSQKITLHVPAN------ATGVAHYVQESSYLYTVQLKLLFS-----SPGQKITFSSQAICAPDLSVACNVTHMSLTIPEFPG-------KLKSVGFGQRNIPEDQWHANGIDKEATNG--------LRLHFRKSLLKTKP-------------------------------------------SEKCPFYQFYFSS----------------------------------LELTFNFQGDMLSTVIDPECHCESPVSID--ELCTRDGFMDFEVYS---------------------HQTKPALNLESLLVGNSSCQPIFKVQSLGLARFHIPLNGCGTRQKFEGDKVIYENEIH-----ALWENPPSNIIFRNSEFRMTVRCHYIRDSMLLRAHIKS--HSSPVASVKPGPLALVLQTYPDISYQRPYRKNEYPLVRYLRQPIYMEVTVLNRNDPNIKLVLDDCWATTFEDPASVPQWQIIMDGCEYELDNYRTTFHAAN-SSAAHSGHYQRFDVKTFAFVSESRGLSSLIYFHCSALICNQA---SPLCSVTCPAPLRNKRE--ASKEGTMTVSLPGPIILLSDDSSSKGVMN------PDSYEIT----------------------KDIASKTLGAVAALVGSAVIIGFICYLHKKRIVRFNS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20239-1", "uniprot_id": "ZP2_MOUSE", "id": "P20239-1", "name": "Zona pellucida sperm-binding protein 2", "aln": "MARWQRKASVSSP----CGRSIYRFLSLLFTLVTSVNSVSLPQSENPAFPGTLICDKDEVRIEFSSRFDMEKWNPSVVDTLGSEILN-CTYALDLERFVLKFPYETCTIKVVGGYQVNIRVGDTTTDVRYKDDMYHFFCPAIQAETHE--ISEIVVCRRDLISFSFPQLFSRLADENQ---------------------------------------------------------------------------------------NVSEMGWIVKIGN----------------------------------------GTRAHILPLKDAIVQGFNLLIDSQKVTLHVPAN------ATGIVHYVQESSYLYTVQLELLFS-----TTGQKIVFSSHAICAPDLSVACNATHMTLTIPEFPG-------KLESVDFGQWSIPEDQWHANGIDKEATNG--------LRLNFRKSLLKTKP-------------------------------------------SEKCPFYQFYLSS----------------------------------LKLTFYFQGNMLSTVIDPECHCESPVSID--ELCAQDGFMDFEVYS---------------------HQTKPALNLDTLLVGNSSCQPIFKVQSVGLARFHIPLNGCGTRQKFEGDKVIYENEIH-----ALWENPPSNIVFRNSEFRMTVRCYYIRDSMLLNAHVKG--HPSPEAFVKPGPLVLVLQTYPDQSYQRPYRKDEYPLVRYLRQPIYMEVKVLSRNDPNIKLVLDDCWATSSEDPASAPQWQIVMDGCEYELDNYRTTFHPAG-SSAAHSGHYQRFDVKTFAFVSEARGLSSLIYFHCSALICNQVSLDSPLCSVTCPASLRSKRE--ANKEDTMTVSLPGPILLLSDVSSSKGVD-------PSSSEITKDII-----------------AKDIASKTLGAVAALVGSAVILGFICYLYKKRTIRFNH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05996-1", "uniprot_id": "ZP2_HUMAN", "id": "Q05996-1", "name": "Zona pellucida sperm-binding protein 2", "aln": "MACRQRGGSWSPSGWFNAGWSTYRSISLFFALVTSGNSIDVSQLVNPAFPGTVTCDEREITVEFPSSPGTKKWHASVVDPLGLDMPN-CTYILDPEKLTLRATYDNCTRRVHGGHQMTIRVMNNSAALRHGAVMYQFFCPAMQVEETQG-LSASTICQKDFMSFSLPRVFSGLADDSKG--------------------------------------------------------------------------------------TKVQMGWSIEVGD----------------------------------------GARAKTLTLPEAMKEGFSLLIDNHRMTFHVPFN------ATGVTHYVQGNSHLYMVSLKLTFI-----SPGQKVIFSSQAICAPDP-VTCNATHMTLTIPEFPG-------KLKSVSFENQNIDVSQLHDNGIDLEATNG--------MKLHFSKTLLKTKL-------------------------------------------SEKCLLHQFYLAS----------------------------------LKLTFLLRPETVSMVIYPECLCESPVSIVTGELCTQDGFMDVEVYS---------------------YQTQPALDLGTLRVGNSSCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKVVYENEIH-----ALWTDFPPSKISRDSEFRMTVKCSYSRNDMLLNINVES--LTPPVASVKLGPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVG-SSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPDSPLCSVTCPVSSRHRRATGATEAEKMTVSLPGPILLLSDDSSFRGVGSSDLKASGSSGEKSRSETGEEVGSRGAMDTKGHKTAGDVGSKAVAAVAAFAGVVATLGFIYYLYEKRTVSNH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PLH2-1", "uniprot_id": "A0A8M1PLH2_DANRE", "id": "A0A8M1PLH2-1", "name": "", "aln": "MSWLLGICTLWLLMVVVLSQKFVEQQVKNFDLVAAQN-FNQRTGLRTECLGSYMKLTIDKSIAFGNQVEIDVVNGSQIEPLTPALAAKCGFSVDSDPWGNHRIFASILNCFAGDEDDTVMEVDMRVRVRGRNNMQSDVYPVTKSCTYDRWASREILCERNYMEVSVNRMPEEITALRRQKPKLARAFSSNQWAGTVSEAITSKYNIWRMVFFTPEQKAMVLEDALKAGHGITTTRSRLAIRTGYDMPETYVENVSGVPMKIIKVTTYFKKQWSVTMLDTVAACPIGGLSFTDEMITWSFPWKNHLLGTSDIIIHEMLMGIDGRLIDSAHMAARGFILTRNDDFIVMKLPIGGPDGYTKSGVVENLYHTRYVIEPMLELLWSEGGMDSTRYRVLFPVKTPLMPRPLQLVDLTVVEQRIFDVVLGPFLHDVELVNITFSGVVLTVMEANARGFNIQDQVFQNGSKSFRLNVPFTDTLVVRTQTDLLATTYTLPIIYGFMIVPEYVAFSYVTSVQVTFQDIVLPTVTGSCDKEQFYITISNGNLGVDYNIMLGTRDLNQELRAEYGIRDNGTHLTLAVPFLSLDVAFELMYSTSLRARVDVLVWEPVSKRSLSDFSLACNFPMTMTECFSNGSISALAVKVESVPQLVPKNLRLQDPSCRPKFSNDR--FAYFSFDANSCGTTRTFYDGVMMYQNEITSGDGLQVFQQANKELASPSPDYRVTVSCFYTLNETQMISFTSQPLVRAPMVETGYGELHVVMRLALDGSYSNFYAEEDYPVTRYLRSPLFFEVMLLQSTDPRIELVLENCWATVNEGRESTPRWDLIVDGCVNLGDTRRTHFHSVTPEMAQYPTHVKHFEIKMFTFMKDSVVSQDQIFVHCDAVLCAVN-QADGICQRQCPS--------------------PNPLNSRNKVR------------------------------------------RDVANDRFQRTLLSSGKIHLSSS--------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * **:: * .. .. *: : : * . . : * ::.: : * : :* : : : . . *. : .: : . : : . *. : : * :* .: :..*. :: . :: : . : * : : : * : : . .** * :.. :.:::* . :*:.. : . :: *:* : :. :: *. :: * : * : * :. :* .: * : : : .*:: : :.: * .:*: . : .* ***:: * *:. : :: : . .: *.: * :: .: *..: . :: * * .* : :.**:* *. : :. * : *.*** .* .. ::*:*** :: : . ..::*:** * * :. : . .* . . * : :::: * **.. * :::**:.*:**.*:::** :*. **.*:***::**** . * *:*::::*** *. :* **.. . . :. * ::*::* *:*:.:: .. ::.**.*::* . :*. ** *.*: .. *:... . . * . ", "identical_positions": 115, "similar_positions": 232, "identity": "11.42%" }, { "cls_id": "homologset.agr.RGD:620606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97708-1", "uniprot_id": "ZP3_RAT", "id": "P97708-1", "name": "Zona pellucida sperm-binding protein 3", "aln": "-----------------------------------------------------------------MGPSCLLFLCLLLCG-------GPELCYPQTQWLLPGGTPTPAGSSSPVEVECKEAELVVTVRRDLFGTGKLVQPGDLTLGSEGCQPLVAVDT--DVVRLNAQLHECSSGVQVTEDALVYNTFLLHDPRPVNGLSILRTNRVEVPIECRYPRQGNVSSHPIQPTWVPFSATVSSEEKLAFSLRLMEEDWNTEKSSPTFHLGEVAHLQAEVQTGSHLPLQLFVDHCVATPSPLPGQNSSPHHFIVDSHGCLVDGLSESFSAFQVPRPRPETLQFTVDVFHFANSSRNTVYITCHLKVAPANQIPDKLNKACSFNKTSQSWLPVEGDADICDCCSNGNCSNSSSSEFETHEPAQWSTLVSRNRRHVTDEADVTVGPLIFLGKANDQAVEGWTSSAQTS-VALGLGLATVAFLTLAAIVLGVTRKCHTSSYLVSLPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10761-1", "uniprot_id": "ZP3_MOUSE", "id": "P10761-1", "name": "Zona pellucida sperm-binding protein 3", "aln": "-----------------------------------------------------------------MASSYFLFLCLLLCG-------GPELCNSQTLWLLPGGTPTPVGSSSPVKVECLEAELVVTVSRDLFGTGKLVQPGDLTLGSEGCQPRVSVDT--DVVRFNAQLHECSSRVQMTKDALVYSTFLLHDPRPVSGLSILRTNRVEVPIECRYPRQGNVSSHPIQPTWVPFRATVSSEEKLAFSLRLMEENWNTEKSAPTFHLGEVAHLQAEVQTGSHLPLQLFVDHCVATPSPLPDPNSSPYHFIVDFHGCLVDGLSESFSAFQVPRPRPETLQFTVDVFHFANSSRNTLYITCHLKVAPANQIPDKLNKACSFNKTSQSWLPVEGDADICDCCSHGNCSNSSSSQFQIHGPRQWSKLVSRNRRHVTDEADVTVGPLIFLGKANDQTVEGWTASAQTS-VALGLGLATVAFLTLAAIVLAVTRKCHSSSYLVSLPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21754-1", "uniprot_id": "ZP3_HUMAN", "id": "P21754-1", "name": "Zona pellucida sperm-binding protein 3", "aln": "-----------------------------------------------------------------MELSYRLFICLLLWG-------STELCYPQPLWLLQGGASHPETSVQPVLVECQEATLMVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTE-DVVRFEVGLHECGNSMQVTDDALVYSTFLLHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPT--PDQNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCGTPSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWALPSDTSVVLLGVGLAVVVSLTLTAVILVLTRRCRTASHPVSASE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286Y9R5-1", "uniprot_id": "A0A286Y9R5_DANRE", "id": "A0A286Y9R5-1", "name": "Zona pellucida sperm-binding protein 3", "aln": "MEFLQGVLVLAVLAVFDLTNAQGSLSNVQSPRGFNMNLRGVPAPPGAVFSPDVMVAFNSLDSRKPVQAPLSLQEKLMLQAPEPFTWKFPIVAEAQREFATNFQLKQPASPGSTVAVNCGSDRVHVEVQQDLFSNGELIQPAGLTLGG---RPVVGQDPNSGVFIFEYATQDPESVVMMTEDELVYTYTLTYTPEAFPGTPIIRTNSAVVGVQCHYPRLHNVSSNALMPAWTPYASSEVGEDILVFSLNLMTDDWSYQRPSNVYFLGSVINIEASVMQYNHVPLRVYVDRCVATPVP--DPEALPRYSFIENHGCFVDAKITGSSSHFLPITQEDKLRFQLEAFMFQDTPSPLIYITCIVKATVAARHSDHLHKSCSFAN---GWFANDGHHGACNCCDS-TCGHGSVEG----------QLTGDGYRGLQWEGKALVGPVVVKDTQRNLV-------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * *:* . . :. .* : * . ..* *:* . : * * :***..*:*::...**** .* *. *. .*. :: :: . : :*.* ***. * : *... . .*:*** . : ::*:*** ****:.: *:* *: :: .*: *.***.** ::*. :: : .:.**.. :::*.: .*:**:::**:***** . :: * : ::: ***:**. . *:. :* . :.*:* ::.* * : . :**** :*.: * : .*.*:*:*** : .*:. :* . *:**. *. * . .. . * : *... ***::. . : ", "identical_positions": 102, "similar_positions": 136, "identity": "20.44%" }, { "cls_id": "homologset.agr.RGD:620607", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11240-1", "uniprot_id": "COX5A_RAT", "id": "P11240-1", "name": "Cytochrome c oxidase subunit 5A, mitochondrial", "aln": "MLAAALRRCTAAAAAR----GLLHPVSAPSPAAAVCSIRCYSHGSHETDEEFDARWVTYFNKPDIDAWELRKGMNTLVGYDLVPEPKIIDAALRACRRLNDFASAVRILEVVKDKAGPHK-EIYPYVIQELRPTLNELGISTPEELGLDKV----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12787-1", "uniprot_id": "COX5A_MOUSE", "id": "P12787-1", "name": "Cytochrome c oxidase subunit 5A, mitochondrial", "aln": "MLAAALRRCTAAAAAR----GLLHPASAPSPAAAVCSIRCYSHGSHETDEEFDARWVTYFNKPDIDAWELRKGMNTLVGYDLVPEPKIIDAALRACRRLNDFASAVRILEVVKDKAGPHK-EIYPYVIQELRPTLNELGISTPEELGLDKV----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20674-1", "uniprot_id": "COX5A_HUMAN", "id": "P20674-1", "name": "Cytochrome c oxidase subunit 5A, mitochondrial", "aln": "MLGAALRRCAVAATTRADPRGLLHSARTPGPAVAIQSVRCYSHGSQETDEEFDARWVTYFNKPDIDAWELRKGINTLVTYDMVPEPKIIDAALRACRRLNDFASTVRILEVVKDKAGPHK-EIYPYVIQELRPTLNELGISTPEELGLDKV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q94514-1", "uniprot_id": "COX5A_DROME", "id": "Q94514-1", "name": "Cytochrome c oxidase subunit 5A, mitochondrial", "aln": "MLSITAR--NLASALR---------SSLVGTSSRVAAVRCL-HGTEESAEEFDKRYEKYFSREGIDGWEIRKGMNDLLGMDLVPSPKIIEAGLRASRRVNDIALAIRWLEGCKDKCGDQKATLYPYLLEKITPTLQELGIPTIEELGYDKPELALKSVYDA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00427-1", "uniprot_id": "COX6_YEAST", "id": "P00427-1", "name": "Cytochrome c oxidase subunit 6, mitochondrial", "aln": "MLSRAIFRNPVINRTLLRARPGAYHATRLTKNTFIQSRKYSDAHDEETFEEFTARYEKEFD-EAYDLFEVQRVLNNCFSYDLVPAPAVIEKALRAARRVNDLPTAIRVFEALKYKVENED--QYKAYLDELKDVRQELGVPLKEELFPSSS----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. : : : : .*: *** *: . *. * :*::: :* . *:** * :*: .***.**:**:. ::* :* * * .. * :::: . :***:. *** .. ", "identical_positions": 34, "similar_positions": 39, "identity": "21.12%" }, { "cls_id": "homologset.agr.RGD:620608", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12075-1", "uniprot_id": "COX5B_RAT", "id": "P12075-1", "name": "Cytochrome c oxidase subunit 5B, mitochondrial", "aln": "--------------------------MASRLLRGVGALAAQALRAHGPRGVAATRSMASGGGVPTDEEQATGLEREIMIAAQRG-LDPYNMLPPKA-ASGTKEDPNLVPSVSNKRIVGCICE-EDNCTVIWFWLHQGESQRCPNCGTHYKLVPYQMVH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19536-1", "uniprot_id": "COX5B_MOUSE", "id": "P19536-1", "name": "Cytochrome c oxidase subunit 5B, mitochondrial", "aln": "--------------------------MASRLLRGVGALAAQALRRT-ARGAAVTRSMASGGGVPTDEEQATGLEREIMIAAQKG-LDPYNMLPPKA-ASGTKEDPNLVPSISNKRIVGCICE-EDNCTVIWFWLHKGESQRCPNCGTHYKLVPHQMAH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10606-1", "uniprot_id": "COX5B_HUMAN", "id": "P10606-1", "name": "Cytochrome c oxidase subunit 5B, mitochondrial", "aln": "--------------------------MASRLLRGAGTLAAQALRARGPSGAAAMRSMASGGGVPTDEEQATGLEREIMLAAKKG-LDPYNVLAPKG-ASGTREDPNLVPSISNKRIVGCICE-EDNTSVVWFWLHKGEAQRCPRCGAHYKLVPQQLAH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A3X0-1", "uniprot_id": "A0AB13A3X0_DANRE", "id": "A0AB13A3X0-1", "name": "Cytochrome c oxidase subunit 5B, mitochondrial", "aln": "--------------------------MAARLLLRS-ATRAVVLRHRTLPAPAVARALASGG-IPTDDEQATGLERIVMEASKKG-LDPYNILKPKE-YAGSKQDPHIVPSISTKRIVGCVCE-EDNTAVVWFWLHQGEAQRCPSCGAYYKLVPHELPH-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMB9-1", "uniprot_id": "Q9VMB9_DROME", "id": "Q9VMB9-1", "name": "", "aln": "----------------------------MASICGRMALR----AAARQN--VAYTPVRFCKMMNDPLEHATGIEKRELLLKAAGNDNPFDM-KVFKRGAGTKENPNLIPSAFDARIVGCICE-EDQTYVQWMWLQKGN-QKRCECGHWFKLVEKAAV------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMB8-1", "uniprot_id": "Q9VMB8_DROME", "id": "Q9VMB8-1", "name": "", "aln": "MSSYISRLLKAQSASKRLISNLTQRDGKLSSLLRRLGLQWQGSAAAPQQRPISTTQVQKSALIADD-QLVTGIQKREMLLAKQGCEDPWGFSKVIRRGSGRENDPTVVPSAFDARLVGCLCL-DDR-LPKWMWIEKDEGPKRCECGHYFILKNVPPV------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04037-1", "uniprot_id": "COX4_YEAST", "id": "P04037-1", "name": "Cytochrome c oxidase subunit 4, mitochondrial", "aln": "-------MLSLRQSIRFFKPATRTLCSSRYLLQQKPVVKTAQNLAEVNGPETLIGPGAKEGTVPTDLDQETGLARLELLGKLEG-IDVFDTKPLDSSRKGTMKDPIIIESYDDYRYVGCTGSPAGSHTIMWLKPTVNEVARCWECGSVYKLNPVGVPNDDHHH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : **: : : * : :. * ::* :: * * *** . *: .: : ** : * ", "identical_positions": 14, "similar_positions": 19, "identity": "8.59%" }, { "cls_id": "homologset.agr.RGD:620609", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52949-1", "uniprot_id": "HXA5_RAT", "id": "P52949-1", "name": "Homeobox protein Hox-A5", "aln": "-----------------------------HNYGDHSSVSEQFRDSASMHSGRYGYG-YNGMDLSVGRSGSG----------------------HFGS-------------------------------GEXXRSYXAGASAAPAEPRYSQPATSTHS-PPPDPLPCSAVAPLPGSD-THHGGKNSLGNSSGCSANCG------------------STHISSREGVG-TASAAEE--------------------------------------------DAPASSE-QAGAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGP-EGKRARTCYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDK----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09021-1", "uniprot_id": "HXA5_MOUSE", "id": "P09021-1", "name": "Homeobox protein Hox-A5", "aln": "-------MSSY-FVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYG-YNGMDLSVGRSGSG----------------------HFGS-------------------------------GERARSYAAGASAAPAEPRYSQPATSTHS-PPPDPLPCSAVAPSPGSD-SHHGGKNSLGNSSGASANAG------------------STHISSREGVG-TASAAEE--------------------------------------------DAPASSE-QAGAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGP-EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMS-----MAAAGGAFRP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20719-1", "uniprot_id": "HXA5_HUMAN", "id": "P20719-1", "name": "Homeobox protein Hox-A5", "aln": "-------MSSY-FVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYG-YNGMDLSVGRSGSG----------------------HFGS-------------------------------GERARSYAASASAAPAEPRYSQPATSTHS-PQPDPLPCSAVAPSPGSD-SHHGGKNSLSNSSGASADAG------------------STHISSREGVG-TASGAEE--------------------------------------------DAPASSE-QASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGP-EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMS-----MAAAGGAFRP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9YGT6-1", "uniprot_id": "HXA5A_DANRE", "id": "Q9YGT6-1", "name": "Homeobox protein Hox-A5a", "aln": "-------MSSY-FVNSFCGRYPNGVDYPLHNYGDHNS-SGQCRDSTGMHSGRYACG-YNGMDLSTGHSSPG----------------------HFLSS------------------------------GERTQSYKDSPTATP--VRYNQPVTASSAEPSSDHLPCSSLANSPVSEQSHRALKISLSSTAGSASKSF------------------GTVLS-REGVSKVSSSMEE--------------------------------------------EKPPGSG-QTASQN-VSEAP----QIYPWMRKLHISHDNLAGP-EGKRPRTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDNKLKSMN-----MAAAGSGYRP-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09077-1", "uniprot_id": "SCR_DROME", "id": "P09077-1", "name": "Homeotic protein Sex combs reduced", "aln": "MDPDCFAMSSYQFVNSLASCYPQQMNPQQNHPGAGNSSAGGSGGGAGGSGGVVPSGGTNGGQGSAGAATPGANDYFPAAAAYTPNLYPNTPQAHYANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKYANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHMGPYGHPYHQFDIHPSQFAHLSA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * .* : ..:. .* * ** : *.* : .* *: . : ::: .. *: : * . : .. * * : . * ... . ::.. .. :* . * .: . :: : ..* ::.:.. . . ******:::*:. ..: . * ** **.*****************************:***:*****************:: ", "identical_positions": 79, "similar_positions": 71, "identity": "18.94%" }, { "cls_id": "homologset.agr.RGD:62061", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV41-1", "uniprot_id": "INSL6_RAT", "id": "Q9WV41-1", "name": "Insulin-like peptide INSL6", "aln": "MKQLCCSCLLWLGLLLAPFSQEQEEVTSPTKLCGRDLLVEVIKLCGQNDWSRFSMEEQSPMTELVPQYTRKVKTFN------PHRSSSSWGRFTNP---GVSQKKATHTWESQSLPNYQLKK-EELLPKTGVHS-YHGGKPYVKS-VKFQKKNTDKMSTFSGLFWGNHPQRKRRGFADKCCAIGCSKEELAVACLPFVDF---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QY05-1", "uniprot_id": "INSL6_MOUSE", "id": "Q9QY05-1", "name": "Insulin-like peptide INSL6", "aln": "MKQLCCSCLLWLGLLLTPFSREEEEESRPRKLCGRHLLIEVIKLCGQSDWSRFEMEEQSPMTQFFPHYSRKGKAFN------PHPSSSAWRRFTNPVPAGVSQKKGTHTWEPQSLPDYQFEK-TELLPKARVFS-YHSGKPYVKS-VQLQKKSTNKMNTFRSLFWGNHSQRKRRGFADKCCVIGCTKEEMAVACLPFVDF---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y581-1", "uniprot_id": "INSL6_HUMAN", "id": "Q9Y581-1", "name": "Insulin-like peptide INSL6", "aln": "MPRLLRLSLLWLGLLLVRFSRELSDISSARKLCGRYLVKEIEKLCGHANWSQFRFEEETPFSRLIAQASEKVEAYSPYQFESPQTASPARGRGTNP--VSTSWEEAVNSWEMQSLPEYKDKKGYSPLGKTREFSSSHNINVYIHENAKFQKKRRNKIKTLSNLFWGHHPQRKRRGYSEKCCLTGCTKEELSIACLPYIDFKRLKEKRSSLVTKIY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :* .********. **:* .: : . ***** *: *: ****: :**:* :**::*::.:..: :.* :::. *: :*.: * *** ..* ::..::** ****:*: :* . * *: .* *. : *::. .::*** :*:.*: .****:*.******:::*** **:***:::****::** ", "identical_positions": 81, "similar_positions": 71, "identity": "37.67%" }, { "cls_id": "homologset.agr.RGD:620610", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88867-1", "uniprot_id": "KMO_RAT", "id": "O88867-1", "name": "Kynurenine 3-monooxygenase", "aln": "--------------------MASSDTEGKRVVVIGGGLVGALNACFLAKRNFQVDVYEAREDIRVANFMRG--RSINLALSYRGRQALKAVG--LEDQIVSKGVPMKARMIHSLSGKKSAIPYG-NKSQYILSISREKLNKDLLTAVESYPNAKVHFGHKLSKCCPEEGI----LTMLGPNKVPRDITCDLIVGCDGAYSTVRAHLMKKPRFDYSQQYIPHGYMELTIPP-------KNGEYAMEPNCLHIWPRNAFMMIALPNMDKSFTCTLFMSFEEFEKLPTH-SDVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPMISVKCSPFHLKS-RCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNDLSVCLPEFSRFRIPDDHAISDLSMYNYIEMRAHVNSRWFLFQRLLDKFLHALMPSTFIPLYTMVAFTR-IRYHEAVLRWHWQKKVINRGLFVLGSLVAIGSAYILVHHLSPRPLELLR------SAWTGTSGHWNRSADISPRVP--WSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WN4-1", "uniprot_id": "KMO_MOUSE", "id": "Q91WN4-1", "name": "Kynurenine 3-monooxygenase", "aln": "--------------------MASSDTQGKRVAVIGGGLVGALNACFLAKRNFQVDVYEAREDIRVAKSARG--RSINLALSYRGRQALKAIG--LEDQIVSKGVPMKARMIHSLSGKKSAIPYG-NKSQYILSISRENLNKDLLTAVESYANAKVHFGHKLSKCIPEEGV----LTVLGPDKVPRDVTCDLVVGCDGAYSTVRAHLMKKPRFDYTQQYIPHGYMELTIPP-------KNGEYAMEPNCLHIWPRNAYMMIALPNMDKSFTCTLFMPFEEFERLPTR-SDVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPMISVKCSPFHLKS-HCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNNLSMCLPEFSRFRIPDDHAISDLSMYNYIEMRAHVNSRWFLFQKLLDKFLHAIMPSTFIPLYTMVAFTR-IRYHEAVLRWHWQKKVINRGLFVLGSLIAIGGTYLLVHHLSLRPLEFLRR-----PAWMGTTGYWTRSTDISLQVP--WSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15229-1", "uniprot_id": "KMO_HUMAN", "id": "O15229-1", "name": "Kynurenine 3-monooxygenase", "aln": "--------------------MDSSVIQRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDTRVATFTRG--RSINLALSHRGRQALKAVG--LEDQIVSQGIPMRARMIHSLSGKKSAIPYG-TKSQYILSVSRENLNKDLLTAAEKYPNVKMHFNHRLLKCNPEEGM----ITVLGSDKVPKDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPHGYMELTIPP-------KNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFEEFEKLLTS-NDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKS-HCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSR-IRYHEAVQRWHWQKKVINKGLFFLGSLIAISSTYLLIHYMSPRSFLRLRRPWNWIAHFRNTTCFPAKAVDSLEQISNLISR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1RLY6-1", "uniprot_id": "KMO_DANRE", "id": "Q1RLY6-1", "name": "Kynurenine 3-monooxygenase", "aln": "------------METAFSHPPQSSSSKRKVIAVVGGGLVGSLNACFLAKRGFDVEVYESREDIRQAKVVKG--RSINLALSHRGRQALKHVG--MEDKIISKGIPMHARMIHNVNGKRSPIPYG-KKGQYILSVDRANLNKELLTAAEAYPNTRLNFNHKLHDWSPKTGT----MTFIGSDGQKTETQADLIVGCDGAFSAVRKQFLRQSRFNYSQTYIPHGYMELTMPP-------KDGDFAMEPNYLHIWPRNTFMMIALPNLDRTFTCTLFMPFEDFEKIRTG-DELLRFFHKYFPDSVPLIGVEALKQDFFRLPAQAMVSVKCCPYHLFE-KCVLMGDAAHAVVPFYGQGMNAGFEDCLVFDEIMDQFNENLVAVLQEYTRVRVPDDHAIADLAMYNYIEMRAHVNSKYFIFRKYLDNLLHFFMPKTIVPLYTMVTFTR-TRYNDAVNRWHWQNKVITRGLWLCGFVSAAGGTYVLVKNSHKLP-------------SISAEQLWTRILALKLF-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z746-1", "uniprot_id": "KMO_DROME", "id": "A1Z746-1", "name": "Kynurenine 3-monooxygenase", "aln": "MSPGIVSQEVNGRQEPTEAARDERHGRRRRVAVIGAGLVGSLAALNFARMGNHVDLYEYREDIRQALVVQG--RSINLALSQRGRKALAAVG--LEQEVLATAIPMRGRMLHDVRGNSSVVLYDPINNQCLYSVGRRQLNEVLLNACDKLPNIRCHFEHKLTSANLREGS----MEFRNPAKEAVAAHADLIVGCDGAFSSVRQNNVRLPGFNYSQEYIETGYLELCIPS-------KSGDFQMPANYLHIWPRNTFMMIALPNQDKSFTVTLSMPFEIFAGIQNQ-NDLLEFFKLNFRDALPLIGEQQLIKDFFKTRPQFLVSIKCRPYHYAD-KALILGDAAHAMVPYYGQGMNAGMEDVTLLTDILAKQLP-LDETLALFTESRWQDAFAICDLAMYNYVEMRDLTKRWTFRLRKWLDTLLFRLFPG-WIPLYNSVSFSS-MPYRQCIANRKWQDQLLKR-IFGATFLAAIVTGGAIYAQRFL---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38169-1", "uniprot_id": "KMO_YEAST", "id": "P38169-1", "name": "Kynurenine 3-monooxygenase", "aln": "--------------------------MSESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSINLAISARGIDALKSIDPDACEHILQDMIPMKGRMIHDLKGRQESQLYG-LHGEAINSINRSVLNNSLLDELEKS-TTELKFGHKLVKIEWTDDKQICHFAIGEDLKTPHTEKYDFVIGCDGAYSATRSQMQRKVEMDFSQEYMNLRYIELYIPPTEEFKPNYGGNFAIAPDHLHIWPRHKFMLIALANSDGSFTSTFFGSKDQISDLITSKSRVREFLIENFPDIINIMDLDDAVKRFITYPKESLVCVNCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRILMALLKKHSGDRSRAFTEYTQTRHKDLVSITELAKRNYKEMSHDVTSKRFLLRKKLDALFSIIMKDKWIPLYTMISFRSDISYSRALERAGKQTRILKFLESLTLGMLSIGGYKLFKFLTRERS-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.::*.****.* * ::: . .: :*: *:* * . :*****:* ** .** :. :.:: :**:.**:*.: *. . *. :.: : *:.* **: ** : . . :* *:* . . : . *:::*****:*:.* : : ::::* *: *:** :*. .*:: : .: ******: :*:***.* : :** *: . : : : . . : *: * * : ::. . : *: : ::.::* .:. :.:::******:**::*****.*:** :: :: : : ::. * * :* :*: ** ** .. * ::: :: :: :: :***. ::* * .: . * :::. : : : ", "identical_positions": 102, "similar_positions": 151, "identity": "19.43%" }, { "cls_id": "homologset.agr.RGD:620611", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIF3-1", "uniprot_id": "SL2A8_MOUSE", "id": "Q9JIF3-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPEDPQETQPLLRPPEARTPRGRR---------------------------------------------------------------------------------------------------------------------------------------------------VFLASFAAALGPLSFGFALGYSS---PAIPSLRRT-----APPALRLGDNAASWFGAVVTLGAAAGGILGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-------VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAG-------WVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWGSEEGWE-------------EPPVGAEHQGFQLALL----RRPGIYKPLIIGISLMVFQQLSGVNAIMFYANSIFEEAKF-KDSSLASVTVGIIQVLFTAVAALIMDRAGRRLLLALSGVIMVFSMSAFG----TYFKLTQSLPSNSSHVG-LVPIAAEPVDVQVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRPYGAFWLTAAFCALSVLFTLTVVPETKGRTLEQVTAHFEGR----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJZ1-1", "uniprot_id": "SL2A8_RAT", "id": "Q9JJZ1-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPEDPQETQPLLRSPGARAPGGRR---------------------------------------------------------------------------------------------------------------------------------------------------VFLATFAAALGPLSFGFALGYSS---PAIPSLRRT-----APPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARD-------VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAG-------WVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWGSEEGWE-------------EPPVGAEHQGFQLAML----RRPGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKF-KDSSLASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFG----TYFKLTQSGPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NY64-1", "uniprot_id": "SL2A8_HUMAN", "id": "Q9NY64-1", "name": "Solute carrier family 2, facilitated glucose transporter member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPEDPEETQPLLGPPGGSAPRGRR---------------------------------------------------------------------------------------------------------------------------------------------------VFLAAFAAALGPLSFGFALGYSS---PAIPSLQRA-----APPAPRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQD-------VWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAG-------WVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWE-------------DPPIGAEQS-FHLALL----RQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKF-KDSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFG----AYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MKK4-1", "uniprot_id": "TRE12_DROME", "id": "Q8MKK4-1", "name": "Trehalose transporter 1-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILMRADTHVSFSVP-----ADGLKAN-----------------------------------------------------------------------------------------------------------------------------------------------FTFSQVLAALSVSLCSLVVGFVSAYTS---PALVSMTDR-----TITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVN-------VIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAG-------SFMNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKEL----MQSQADADRQATQNTCLEL----FKRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILG----GFFYCKA-HGPDVSHLG-----------------WLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP-MSSVVNIKPFPFNM-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8N1-1", "uniprot_id": "TRE11_DROME", "id": "A1Z8N1-1", "name": "Trehalose transporter 1", "aln": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTS---PALVSMTDR-----NITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVN-------VAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAG-------SFMNWSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGL----MRSQADADRQASRNTMLEL----LKLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLG----GFFYCKT-YGPDVSHLG-----------------WLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU17-1", "uniprot_id": "Q9VU17_DROME", "id": "Q9VU17-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNS-----------------------------------------------------------------------------------------------------------------------------------------------QKWPQYVAALAAAGGAFAAGTVLGWTS---PAETEIVDRG----EGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVN-------VSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVG-------AGVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAEL----RETDRETKANKVN-VWAAL----NRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIG----VYFFLQKQDAAQVVSLG-----------------WLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU1-1", "uniprot_id": "A8JQU1_DROME", "id": "A8JQU1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSEKVVRAMARWWQTVSQEDGD----------------SRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTA-----------------------------------------------------------------------------------------------------------------------------------------------LSWTSPVFPQISAGNESSFNSTTGGIS---NSTSNEND----------IRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANS-------VGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVG-------ALVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWG-DYCNTSNAIQA----IQNDLDQTGVDAS-VKDLF----SNRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSST-LNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLG----AYNTINR-HTDLSQSIG-----------------WLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAG-GADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40885-1", "uniprot_id": "HXT9_YEAST", "id": "P40885-1", "name": "Hexose transporter HXT9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGVNNTSANDLSTTE---------SNSNSVANAP-------------SVKTEHNDSKNSLNLDATEPPIDLPQKPLS-----------------------------------------------------------------------------------------------------------------------------------------------AYTTVAILCLMIAFGGFIFGWDTGTISGFVNLSDFIRRFG-QKNDKGTYYLSKVRMGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINK------WYQYFIGRIISGLGVGGIAVLSPMLISEVAPKQIRGTLVQLYQLMCTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAWTTFMVSGMMFVPESPRYLIEVGKDEEAKRSLSKSNKVSVDDPALLAEYDTIKAGIELEKLAGNASWSELLS----TKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGL-KDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSSHQDITSQG---------------AGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLIS-FFTPFITGAINFYYGYVFLGCLVFAYFYVFFFVPETKGLTLEEVNTMWLEGVPAWKSASWVPPERRTADYDADAIDHDDRPIYKRFFSS--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P54862-1", "uniprot_id": "HXT11_YEAST", "id": "P54862-1", "name": "Hexose transporter HXT11", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGVNNTSANELSTTM---------SNSNSAVGAP-------------SVKTEHGDSKNSLNLDANEPPIDLPQKPLS-----------------------------------------------------------------------------------------------------------------------------------------------AYTTVAILCLMIAFGGFIFGWDTGTISGFVNLSDFIRRFG-QKNDKGTYYLSKVRMGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINK------WYQYFIGRIISGLGVGGIAVLSPMLISEVAPKHIRGTLVQLYQLMGTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAWATFMVSGMMFVPESPRYLIEVGKDEEAKRSLSKSNKVSVDDPALLVEYDTIKAGIELEKLAGNASWSELLS----TKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGL-KDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSSHQDITSQG---------------AGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLIS-FFTPFITGAINFYYGYVFLGCLVFAYFYVFFFVPETKGLTLEEVNTMWLEGVPAWKSASWVPPERRTADYDADAIDHDNRPIYKRFFSS--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39003-1", "uniprot_id": "HXT6_YEAST", "id": "P39003-1", "name": "High-affinity hexose transporter HXT6", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQDAAIAEQTPVEH-----LSAVDSASHSVLSTP------------SNKAERDEIKAYGE-GEEHEPVVEIPKRPAS-----------------------------------------------------------------------------------------------------------------------------------------------AYVTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFG-MKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINK------WYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFS----SKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGL-SDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNG--QDQPSSKG---------------AGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIG-FFTPFITGAINFYYGYVFMGCLVFMFFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMAHDDKPLYKRMFSTK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39004-1", "uniprot_id": "HXT7_YEAST", "id": "P39004-1", "name": "High-affinity hexose transporter HXT7", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQDAAIAEQTPVEH-----LSAVDSASHSVLSTP------------SNKAERDEIKAYGE-GEEHEPVVEIPKRPAS-----------------------------------------------------------------------------------------------------------------------------------------------AYVTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFG-MKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINK------WYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFS----SKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGL-SDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNG--QDQPSSKG---------------AGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIG-FFTPFITGAINFYYGYVFMGCLVFMFFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMTHDDKPLYKRMFSTK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32467-1", "uniprot_id": "HXT4_YEAST", "id": "P32467-1", "name": "Low-affinity glucose transporter HXT4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEEAAYQEDTAVQNTPADALSPVESDSNSALSTP------------SNKAERDDMKDFDENHEESNNYVEIPKKPAS-----------------------------------------------------------------------------------------------------------------------------------------------AYVTVSICCLMVAFGGFVFGWDTGTISGFVAQTDFIRRFG-MKHHDGTYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINK------WYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHIRGTLVSCYQLMITLGIFLGYCTNYGTKTYTNSVQWRVPLGLGFAWALFMIGGMTFVPESPRYLVEVGKIEEAKRSIALSNKVSADDPAVMAEVEVVQATVEAEKLAGNASWGEIFS----TKTKVFQRLIMGAMIQSLQQLTGDNYFFYYGTTVFTAVGL-EDSFETSIVLGIVNFASTFVGIFLVERYGRRRCLLWGAASMTACMVVFASVGVTRLWPNG--KKNGSSKG---------------AGNCMIVFTCFYLFCFATTWAPIPFVVNSETFPLRVKSKCMAIAQACNWIWGFLIG-FFTPFISGAIDFYYGYVFMGCLVFSYFYVFFFVPETKGLTLEEVNTLWEEGVLPWKSPSWVPPNKRGTDYNADDLMHDDQPFYKKMFGKK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32466-1", "uniprot_id": "HXT3_YEAST", "id": "P32466-1", "name": "Low-affinity glucose transporter HXT3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSTPDLISPQKSSEN---SNADLPSNSSQVMNMP---------------EEK--GVQDDF-QAEADQVLTNPNTGKG-----------------------------------------------------------------------------------------------------------------------------------------------AYVTVSICCVMVAFGGFVFGWDTGTISGFVAQTDFLRRFG-MKHKDGSYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINK------WYQYFIGRIISGLGVGGIAVLSPMLISEVAPKEMRGTLVSCYQLMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLVEAGQIDEARASLSKVNKVAPDHPFIQQELEVIEASVEEARAAGSASWGELFT----GKPAMFKRTMMGIMIQSLQQLTGDNYFFYYGTTVFNAVGM-SDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLLYGAIGMVCCYVVYASVGVTRLWPNG--EGNGSSKG---------------AGNCMIVFACFYIFCFATTWAPIAYVVISETFPLRVKSKAMSIATAANWLWGFLIG-FFTPFITGAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEVNDMYAEGVLPWKSASWVPTSQRGANYDADALMHDDQPFYKKMFGKK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32465-1", "uniprot_id": "HXT1_YEAST", "id": "P32465-1", "name": "Low-affinity glucose transporter HXT1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSTPDLISPQKSNSS---NSYELESGRSKAMNTP---------------EGKNESFHDNLSESQVQPAVAPPNTGKG-----------------------------------------------------------------------------------------------------------------------------------------------VYVTVSICCVMVAFGGFIFGWDTGTISGFVAQTDFLRRFG-MKHHDGSHYLSKVRTGLIVSIFNIGCAIGGIVLAKLGDMYGRRIGLIVVVVIYTIGIIIQIASINK------WYQYFIGRIISGLGVGGITVLSPMLISEVAPSEMRGTLVSCYQVMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMMFVPESPRYLVEAGRIDEARASLAKVNKCPPDHPYIQYELETIEASVEEMRAAGTASWGELFT----GKPAMFQRTMMGIMIQSLQQLTGDNYFFYYGTIVFQAVGL-SDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLMWGAVGMVCCYVVYASVGVTRLWPNG--QDQPSSKG---------------AGNCMIVFACFYIFCFATTWAPIAYVVISECFPLRVKSKCMSIASAANWIWGFLIS-FFTPFITGAINFYYGYVFMGCMVFAYFYVFFFVPETKGLSLEEVNDMYAEGVLPWKSASWVPVSKRGADYNADDLMHDDQPFYKSLFSRK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38695-1", "uniprot_id": "HXT5_YEAST", "id": "P38695-1", "name": "Probable glucose transporter HXT5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MSELENAHQGPLEGSATVSTNS---NSYNEKSGNSTAPGTAGYNDNLAQAKPVSSYISHEGPPKDELEELQKEVDKQLEKKSKS-----------------------------------------------------------------------------------------------------------------------------------------------DLLFVSVCCLMVAFGGFVFGWDTGTISGFVRQTDFIRRFG-STRANGTTYLSDVRTGLMVSIFNIGCAIGGIVLSKLGDMYGRKIGLMTVVVIYSIGIIIQIASIDK------WYQYFIGRIISGLGVGGITVLAPMLISEVSPKQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWSIFMIVGMTFVPESPRYLVEVGKIEEAKRSLARANKTTEDSPLVTLEMENYQSSIEAERLAGSASWGELVT----GKPQMFRRTLMGMMIQSLQQLTGDNYFFYYGTTIFQAVGL-EDSFETAIVLGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYASVGVTRLWPNG--QDQPSSKG---------------AGNCMIVFACFYIFCFATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLIS-FFTPFITSAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEVNEMYEENVLPWKSTKWIPPSRRTTDYDLDATRNDPRPFYKRMFTKEK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40886-1", "uniprot_id": "HXT8_YEAST", "id": "P40886-1", "name": "Hexose transporter HXT8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDRKTNLPEEPIFEEAEDDGCPSIENSSHLSVPTV-------------EENKD-----FSEYNGEEAEEVVVPEKPAS-----------------------------------------------------------------------------------------------------------------------------------------------AYATVSIMCLCMAFGGFMSGWDTGTISGFVNQTDFLRRFGNYSHSKNTYYLSNVRTGLIVSIFNVGSAIGCLFLSKLGDIYGRCMGLIIVIVVYMVGIVIQIASIDK------WYQYFIGRIIAGIGAGSISVLAPMLISETAPKHIRGTLLACWQLMVTFAIFLGYCTNYGTKTYSNSVQWRVPLGLCFAWAIIMIGGMTFVPESPRFLVQVGKIEQAKASFAKSNKLSVDDPAVVAEIDLLVAGVEAEEAMGTASWKELFS----RKTKVFQRLTMTVMINSLQQLTGDNYFFYYGTTIFKSVGM-NDSFETSIVLGIVNFASCFFSLYSVDKLGRRRCLLLGAATMTACMVIYASVGVTRLYPNG--KSEPSSKG---------------AGNCTIVFTCFYIFCFSCTWGPVCYVIISETFPLRVRSKCMSVATAANLLWGFLIG-FFTPFITSAINFYYGYVFMGCLAFSYFYVFFFVPETKGLTLEEVDEMWMDGVLPWKSESWVPASRRDGDYDNEKLQHDEKPFYKRMF----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P13181-1", "uniprot_id": "GAL2_YEAST", "id": "P13181-1", "name": "Galactose transporter", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVEENNMPVVSQQPQAGEDVISSLSKDSHLSAQSQ-------------KYSNDELKAGESGSEGSQSVPIEIPKKPMS-----------------------------------------------------------------------------------------------------------------------------------------------EYVTVSLLCLCVAFGGFMFGWDTGTISGFVVQTDFLRRFG-MKHKDGTHYLSNVRTGLIVAIFNIGCAFGGIILSKGGDMYGRKKGLSIVVSVYIVGIIIQIASINK------WYQYFIGRIISGLGVGGIAVLCPMLISEIAPKHLRGTLVSCYQLMITAGIFLGYCTNYGTKSYSNSVQWRVPLGLCFAWSLFMIGALTLVPESPRYLCEVNKVEDAKRSIAKSNKVSPEDPAVQAELDLIMAGIEAEKLAGNASWGELFS----TKTKVFQRLLMGVFVQMFQQLTGNNYFFYYGTVIFKSVGL-DDSFETSIVIGVVNFASTFFSLWTVENLGHRKCLLLGAATMMACMVIYASVGVTRLYPHG--KSQPSSKG---------------AGNCMIVFTCFYIFCYATTWAPVAWVITAESFPLRVKSKCMALASASNWVWGFLIA-FFTPFITSAINFYYGYVFMGCLVAMFFYVFFFVPETKGLSLEEIQELWEEGVLPWKSEGWIPSSRRGNNYDLEDLQHDDKPWYKAMLE---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P43581-1", "uniprot_id": "HXT10_YEAST", "id": "P43581-1", "name": "Hexose transporter HXT10", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSSSVSILGT-------------SAKASTSLSR---------------------KDEIKLTPETREASLDIPYKPII-----------------------------------------------------------------------------------------------------------------------------------------------AYWTVMGLCLMIAFGGFIFGWDTGTISGFINQTDFKRRFG-ELQRDGSFQLSDVRTGLIVGIFNIGCALGGLTLGRLGDIYGRKIGLMCVILVYVVGIVIQIASSDK------WYQYFIGRIVSGMGVGGVAVLSPTLISEISPKHLRGTCVSFYQLMITLGIFLGYCTNYGTKKYSNSIQWRVPLGLCFAWAIFMVIGMVMVPESPRYLVEKGKYEEARRSLAKSNKVTVTDPGVVFEFDTIVANMELERAVGNASWHELFS----NKGAILPRVIMGIVIQSLQQLTGCNYFFYYGTTIFNAVGM-QDSFETSIVLGAVNFASTFVALYIVDKFGRRKCLLWGSASMAICFVIFATVGVTRLWPQG--KDQPSSQS---------------AGNVMIVFTCFFIFSFAITWAPIAYVIVAETYPLRVKNRAMAIAVGANWMWGFLIG-FFTPFITRSIGFSYGYVFMGCLIFSYFYVFFFVCETKGLTLEEVNEMYEERIKPWKSGGWIPSSRRTPQPTSSTPLVIVDSK---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P23585-1", "uniprot_id": "HXT2_YEAST", "id": "P23585-1", "name": "High-affinity glucose transporter HXT2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEFATSRVES-------------GSQQTSIHSTP--------------IVQKLETDESPIQTKSEYTNAELPAKPIA-----------------------------------------------------------------------------------------------------------------------------------------------AYWTVICLCLMIAFGGFVFGWDTGTISGFVNQTDFKRRFG-QMKSDGTYYLSDVRTGLIVGIFNIGCAFGGLTLGRLGDMYGRRIGLMCVVLVYIVGIVIQIASSDK------WYQYFIGRIISGMGVGGIAVLSPTLISETAPKHIRGTCVSFYQLMITLGIFLGYCTNYGTKDYSNSVQWRVPLGLNFAFAIFMIAGMLMVPESPRFLVEKGRYEDAKRSLAKSNKVTIEDPSIVAEMDTIMANVETERLAGNASWGELFS----NKGAILPRVIMGIMIQSLQQLTGNNYFFYYGTTIFNAVGM-KDSFQTSIVLGIVNFASTFVALYTVDKFGRRKCLLGGSASMAICFVIFSTVGVTSLYPNG--KDQPSSKA---------------AGNVMIVFTCLFIFFFAISWAPIAYVIVAESYPLRVKNRAMAIAVGANWIWGFLIG-FFTPFITSAIGFSYGYVFMGCLVFSFFYVFFFVCETKGLTLEEVNEMYVEGVKPWKSGSWISKEKRVSEE---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P54854-1", "uniprot_id": "HXT15_YEAST", "id": "P54854-1", "name": "Hexose transporter HXT15", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASEQSSPEINADNLN--------SSAADVHVQPP---------------GEKEWSDGFYDKEVINGNTPDAPKRGFL-----------------------------------------------------------------------------------------------------------------------------------------------GYLIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHK------WYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFS----VKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGL-TDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFASIGVKCLYPHG--QDGPSSKG---------------AGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSKAMSISTAFNWLWQFLIG-FFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGASSRETEAKKKSWKEVLKFPKSFN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47185-1", "uniprot_id": "HXT16_YEAST", "id": "P47185-1", "name": "Hexose transporter HXT16", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASEQSSPEINADNLN--------SSAADVHVQPP---------------GEKEWSDGFYDKEVINGNTPDAPKRGFL-----------------------------------------------------------------------------------------------------------------------------------------------GYLIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHK------WYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKIDKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFS----VKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGL-TDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFASIGVKCLYPHG--QDGPSSKG---------------AGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSKAMSISTAFNWLWQFLIG-FFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEETQLLYEEGIKPWKSASWVPPSRRGASSRETEAKKKSWKEVLKFPKSFN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39924-1", "uniprot_id": "HXT13_YEAST", "id": "P39924-1", "name": "Hexose transporter HXT13", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSAQSSIDSDGDVR-----------DADIHVAPP---------------VEKEWSDGFDDNEVINGDNVEPPKRGLI-----------------------------------------------------------------------------------------------------------------------------------------------GYLVIYLLCYPISFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHK------WYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYDNTAQWRVPLGLCFLWALIIIIGMLLVPESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFS----VKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGL-TDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFASIGVKCLYPHG--QDGPSSKG---------------AGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQFLIG-FFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGISSEESKTEKKDWKKFLKFSKNSD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53631-1", "uniprot_id": "HXT17_YEAST", "id": "P53631-1", "name": "Hexose transporter HXT17", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSTESDRDIQD--------GPDADIHVAPP---------------VEKEWSDGFDDNEVINGDNVEPPKRGLI-----------------------------------------------------------------------------------------------------------------------------------------------GYLVIYLLCYPISFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHK------WYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYDNTAQWRVPLGLCFLWTLIIIIGMLLVPESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFS----VKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGL-TDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFASIGVKCLYPHG--QDGPSSKG---------------AGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQFLIG-FFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGIPSEESKTEKKDWKKFLKFSKGSD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W3S8-1", "uniprot_id": "Q9W3S8_DROME", "id": "Q9W3S8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGQQEEQLVPPPAYKP-----------------------------------TVVAKDTTKDSHAKEKPLGEGRLAVLR--------------------------------------------------------------------------------------------------------------------------------------------------QELMVFLGNSGVLGSGMVVSMPAVTLNQLHDETQP---------FWLNKDESSWFASIQNMACPLGGLLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLG-----YFIRHNIQLIFGISCCYQLAATLLVFPMPESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTIDPVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAG---GNWFPDT--------LG--------------TLHWLPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEELEERWQTGKFSRRLTIVNLKDVELHEVFLKK-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53403-1", "uniprot_id": "GTR3_DROME", "id": "P53403-1", "name": "Glucose transporter type 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRKGGIQDAEPVEPPQS-------------------------------SRKSGTWFAKRPSEMPERHVERAPVRQKIN------------------------------------------------------------------------------------------------------------------------------------------------NVGLYKATLYSNIGSFFFGIAVGWSGTAERSVMEQHSYS--------FQPTELQWSGVCILLTLGAALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFARSVP-------MLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMS-------LFLELRIIN-FVNLGLLALGPLQILMPESPAYYVDHGNIPRAEDSLRFLRGQKYDTRREIDFLTR-----DPTESEREVRQGPLLG---FKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRI---RREFGLILCLGLILGFLACFFLVDRLGRRPLLIFSSAGIVFVSIYLG------LHFKVWMTMGLTVMS-----------------WIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPYLF-LLFAIIASLILLFSLIYIPETKKLSSAKIQQRLGGLINRPAVITFTSSSDSSNA----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . . .. : . * . : .: . *: * .* ** .:: : . : :**:* : * :: . : : * .: : : : . . .:. *:: . : . . : .: : :.: .* : .: . . .: : . : : ** : . ", "identical_positions": 15, "similar_positions": 67, "identity": "1.61%" }, { "cls_id": "homologset.agr.RGD:620612", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70555-1", "uniprot_id": "PTH2R_RAT", "id": "P70555-1", "name": "Parathyroid hormone 2 receptor", "aln": "--------------------------MPWLEALPYICG--------WLILRSCLLVGAQLDSDGTITIEEQIVLVMKAKMQCELNITAQFQEGEGNCFPEWDGLICWPRGTAGKTSAMPCPSYVYDFNHKGVAFRHCTPNGTWDFIHGSNKTWANYSDC--FLQPDINIGKQEFFENLYILYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHLHLFVSFMLRAXSIFVKDRVAQAHLGVEALQSLVMQGDLQNFIGGPSVDKSQYVGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVSFFSDTKYLWGFILIGWGFPAVFVVAWAVARATLADTRCWELSAGDR-WIYXXPILAAIGLNFILFLNTVRVLATKIWETNAVGHDMRKQYRKLAKSTLVLVLVFGVHYIVFICQPHSFSGLWWEIRMHCELFFNSFQGFFVSIVYCYCNGEVQAEVKKTWTRWNLSIDWKKAPPCGGHRYGSVLTTVTHSTSSQSQMGPS---TR-LVLISSKPAKTACR-QIDSHVTLPGYVWSSSEQDCQPQSTPEETKKGHGRQEDDSPVGESSRPVAFTIDTEGCKGESHPI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V95-1", "uniprot_id": "PTH2R_MOUSE", "id": "Q91V95-1", "name": "Parathyroid hormone 2 receptor", "aln": "--------------------------MAWLETFTYICG--------WLILSSCLLVRAQLDSDGTITIEEQIVLVMKAKMQCELNITAQLQEGEGNCFPEWDGIICWPRGTVGKMSAVPCPPYVYDFNHKGVAFRHCTPNGTWDSIHGSNKTWANYSDC--FLQPDINIGKQEFFESLYILYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHLHLFVSFMLRAMSIFVKDRVAQAHLGVEALQSLVMQGDLQNFIGGPSVDKSQYVGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVSFFSDTKYLWGFISIGWGFPAVFVVAWAVARATLADTRCWELSAGDR-WIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDMRKQYRKLAKSTLVLVLVFGVHYIVFVCQPHSFSGLWWEIRMHCELFFNSFQGFFVSIVYCYCNGEVQAEVKKMWTRWNLSIDWKRAPPCGGQRYGSVLTTVTHSTSSQSQMGAS---TR-LVLISGKPTKNACR-QIDSHVTLPGYVWSSSEQDCQTHSPPEETKEGHRRQGDDSPVMESSRPVAFTLDTEGCKGETHPI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49190-1", "uniprot_id": "PTH2R_HUMAN", "id": "P49190-1", "name": "Parathyroid hormone 2 receptor", "aln": "--------------------------MAGLGASLHVWG--------WLMLGSCLLARAQLDSDGTITIEEQIVLVLKAKVQCELNITAQLQEGEGNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRWNLSVDWKRTPPCGSRRCGSVLTTVTHSTSSQSQVAAS---TR-MVLISGKAAKIASR-QPDSHITLPGYVWSNSEQDCLPHSFHEETKEDSGRQGDDILMEKPSRPMESNPDTEGCQGETEDVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GD85-1", "uniprot_id": "A0AC58GD85_DANRE", "id": "A0AC58GD85-1", "name": "", "aln": "MARMLTVSLLILCKPSSSPSPVKIIPVDDLPATAELRASVLRVSLPKTFIKSFLNHLLQAGEDGEITAEEQVQMLLDAKLQCLQKVSSD-DPAVGVCVPEWDGLICWPQGFPGTLTKTPCPGYIYDFNHAAHAYRRCDSNGSWVLAESSNKTWVNYTEC--IKSPEPNKKRQVFFERLHIMYTVGYAVSFSSLLVAIFIIGYFRRLHCTRNYIHMHLFVSFMLRAASIFVKDHVVHTSAGLQEFDAVLMN-NFTNAVDVAPVDTSQYMGCKVTVLLFIYFLATNYYWILVEGLYLHSLIFMAFLSDSKYLWGFTLIGWGVPAVFVAAWAVVRATLADARCWELSAGNIKWIYQVPILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVFVFGVHYIVFVGMPHTFEGLGWEVRMYCELFFNSFQGFFVSIIYCYCNGEVQTEIKKTWTRWNLAFDWKGPVVCGSYRYGSVLTGLNNSTSSQSQLAAGGPGTRSTTLFSSRVYRSSGGPTVSTHATLPGYVLN-SDADSLPPSIPEEP-EDSAKQVDDILLKESLP----TRPSSGLEDDEETL-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : . :: * * * ..** ** ***: :::.**:** ::::: : . * *.*****:****:* *. : *** *:***** . *:*:* .**:* .. ****.**::* : .*: . :* *** *:::*****::**.** ***:****************:********** ******:*.:: *:: :::::*: : * : ..**.***:***::*::********************.***::*:**:****** ****.**.**.****.******:********: *** ***:*********:* ******** **** :* ***************:*********: **:* ** **:**:***************:*********:*:** *:****:.*** . **. * ***** :.:*******:... ** .*:*.: : : .:* ****** . *: *. . * **. :. :* ** : :. . :.* :.: . : ", "identical_positions": 303, "similar_positions": 133, "identity": "51.44%" }, { "cls_id": "homologset.agr.RGD:620613", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88453-1", "uniprot_id": "SAFB1_RAT", "id": "O88453-1", "name": "Scaffold attachment factor B1", "aln": "MAETLSGLGDSGAASAAAVSSAASETGTRRLSDLRVIDLRAELRKRNLTSSGNKSVLMERLKKAIEEEGGNPDEIEVISEGNKKMPKRPSKGKKPEDEGVEDNGLEENSGDGQEDVETSLENLQDMDMMDISVLDEADIDNGSVADCVEEEEEATLPEGLG-LLRIGRLQSKGLPEQLQELAIDDKEAINNVDTSSSDFTILQEMEEASLEPENEKILDILGETCKSEPVKEEGSELEQPFAQATSSVGPDRKLAEEEDLFESCGHPEEEEEEEEEEEQEEEQEEEGDLALASSSKSESSSTRCQWSEADALLAVVKREPAEAPGGGTGMDREPVGLEEPVEQSSTAAQLPETTSQELVRAPTAAPSPEPRDSKDDVKKFAFDACNDVPAAPKESSASEGADQKMSSVEDDSDTKRLSREEKGRSSCGRNFWVSGLSSTTRATDLKNLFSRYGKVVGAKVVTNARSPGARCYGFVTMSTAEEATKCINHLHKTELHGKMISVEKAKSEPAGKRVPDRRDG-----DSKKEKTSTSDRSANLKREEKGDRKDDAKKTDDGSTEKSKDADDQKPG-PSERSRTTKSGSRG----TERTVVMDKSKGVPVISVKTSGSKERASK---SQDRKSVSREKRSVVSFDKVKESR-----KSRDSESR-RERERERSEREQRLQAQWEREERERLEIARERLAFHRHRLERERMERERLERERMHVE-QERRREQERIHREREELRRQQELRYEQERR----------------------------------------------------PAVRRPYEVDGRRDDAYWPEAKRAALDDRYHSDFSRQDRFHDFDHRDRGRYPNHSVDRREGSRSMMGDREGQHYPER----------------HGGPERHGRDSRDGWG-YGSNKRLSEGRGLPLLPRRDWGEHARRLEDDRAWQGTADGGMMERDQQRWQGGERSMSGHSGPGHMMNRGGMSGRGS--------FAPGGASRRHVIPRGGMQAGFGGTEPG-----QQTQ-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YXK2-1", "uniprot_id": "SAFB1_MOUSE", "id": "D3YXK2-1", "name": "Scaffold attachment factor B1", "aln": "MAETLSGLGDASAAGAAAVSSAASETGTRRLSDLRVIDLRAELKKRNLDSSGNKSVLMERLKKAIEDEGGNPDEIEVTSECNKKMPKRPSKGRKPEDEGVEDNGLEENSGDGQEDVETSLENLQDMDMMDISVLDEADIDNGSVADCVEEEEEATLPEGLADSTELVEGDLKGLPEQLQEHAIDDKDTVNNVDTSSSDFTMLQEMEEASLEPENEKILDILGETCKSEPVKEEGSELEQPFAQATSSVGPDRKLAEEEDLFESCGHPEEEEEEEEED-QEEEQEEEGDLALASSSKSESPSTRCQWSEADAPLAVVKREPADAPGGGTGMDREPVGLEEPVEQSSTAAQLPEATSQELVRAPTAALSPEPQDSKEDVKKFAFDACNDVPAPPKESSASEGADQKMSSVEEDSDTKRLSREEKGRSSCGRNFWVSGLSSTTRATDLKNLFSRYGKVVGAKVVTNARSPGARCYGFVTMSTAEEATKCISHLHKTELHGKMISVEKAKSEPTGKRVPDRRDG-----DSKKEKASTSDRSANLKREEKGERKDDAKKTDDGSTEKSKDADDQKPG-PSERSRTTKSGSRG----TERTVVMDKSKGVPVISVKTSGSKERASK---SQDRKSASREKRSVVSFDKVKESR-----KSRDSESR-RERER--SEREQRLQAQWEREERERLEIARERLAFHRHRLERERMERERLERERMHVE-QERRREQERIHREREELRRQQELRYEQERR----------------------------------------------------PAVRRPYEVDGRRDDAYWPEAKRAALDDRYHSDFSRQDRFHDFDHRDRGRYPNHSVDRREGSRSMMGDREGQHYPER----------------HGGPERHGRDSRDGWG-YGSNKRLSEGRGLPPPPRRDWGEHGRRLEDDRAWQGTADGGMMERDHKRWQGGERSMSGHSGPGHMMNRGGMSGRGS--------FAPGGASRGHVIPRGGMQAGFGGQSRG-----SRPSDARFTRRY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15424-1", "uniprot_id": "SAFB1_HUMAN", "id": "Q15424-1", "name": "Scaffold attachment factor B1", "aln": "MAETLSGLGDSGAAGAAALSSASSETGTRRLSDLRVIDLRAELRKRNVDSSGNKSVLMERLKKAIEDEGGNPDEIEITSEGNKKTSKRSSKGRKPEEEGVEDNGLEENSGDGQEDVETSLENLQDIDIMDISVLDEAEIDNGSVADCVEDDDADNLQESLSDSRELVEGEMKELPEQLQEHAIEDKETINNLDTSSSDFTILQEIEEPSLEPENEKILDILGETCKSEPVKEESSELEQPFAQDTSSVGPDRKLAEEEDLFDSA-HPEE-----------------GDLDLASESTAHAQS-----SKADSLLAVVKREPAEQPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDFDACNEVPPAPKESSTSEGADQKMSSPEDDSDTKRLSKEEKGRSSCGRNFWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTAEEATKCINHLHKTELHGKMISVEKAKNEPVGKKTSDKRDS-----DGKKEKSSNSDRSTNLKRDDKCDRKDDAKKGDDGSGEKSKDQDDQKPG-PSERSRATKSGSRG----TERTVVMDKSKGVPVISVKTSGSKERASK---SQDRKSASREKRSVVSFDKVKEPR-----KSRDSESHSRVRER--SEREQRMQAQWEREERERLEIARERLAFQRQRLERERMERERLERERMHVE-HERRREQERIHREREELRRQQELRYEQERR----------------------------------------------------PAVRRPYDLD-RRDDAYWPEAKRAALDERYHSDFNRQDRFHDFDHRDRGRYPDHSVDRREGSRSMMGEREGQHYPER----------------HGGPERHGRDSRDGWGGYGSDKRMSEGRGLPPPPRRDWGDHGRR-EDDRSWQGTADGGMMDRDHKRWQGGERSMSGHSGPGHMMNRGGMSGRGS--------FAPGGASRGHPIPHGGMQGGFGGQSRG-----SRPSDARFTRRY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IMV6-1", "uniprot_id": "Q8IMV6_DROME", "id": "Q8IMV6-1", "name": "", "aln": "-----------------------MPEAGKKIAELRVCDLKSELEKRELETVGPKAVLIERLEKSLRAEGLDPATHLIVPGAKAKKPFAMPMKDLQSEVVIKEEPIDANEEE-------------------VKVEQQDDYQNG---------------------------------NDYSHHADDDGHEIDQVGDVDDECVILDDDDEEDED-----------HVYDDEPQSGDGDAEGKAQDDGAENNGDDKAIIHGEEENTGDTGNMD-----------------NDESINLTIGEDEQKLLHDEASDDKSIKSVKPANKSEKSNSKDADKK--------NDDGARSKKRDEKSGDKKDSSEQKSSGKSSNQKDDK-----EKSTAAPGGATSSTASSAAGSKSGSGSSAGNGTGANSNNK-QATLSRNLWVSGLSTLTRASDLKAIFSKFGKVIGAKVVTNTRTPGTRCYGYVTMSSSADASRCIENLHRTELHGRIISVERTKNEIGGSLNSKEGKGKAPGDAGNKKKEDDSGKKSGSGKGSSSNSGDDKKGGDGNGDSKSVGGDLKRDGKESNRARSRRNDDRGKSLASQDRPRHDRERSAKGSQDHRSGRNPRDVDREIQQRQRERERRQREMLSYQKIREERERQRLRERERELREEERRRREARERQRIEEERLQEERRKLAVERERLEREKAELLRMERERQKLEREKIELERLELKRQQMKIMESRDDPGKRGVSKRADDRYGDVTDRKRTAIFDAPPPPRFDTNLVSSRSTYDKKHDDYGSSSSTKRVLDDYSSSSKRLDYSSKRNDYSSSSGSKRGAVDDYTAVPTKRSNDYSASSSSKRDDYKRDEVRHLPLSGTVGGGSSSSYLHKNNTAGGGAGSYVHKNNTSGTGGRYNDSDRSNTSSYRRDDSHSLGNKRYDNSSGGGGAYGSSSNSVNIWAPSSGGSSSHLGSGGGGGNQIKSYGNNGMSSNMHSTNSWQKSAPVDDNGWRQVPARFDRGYNERSTGYQGQSGGGGAGGMYGASRPAQDRYSGPVSRY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :::::*** **::**.**:: : * *:**:***:*::. ** :* : . : * . . .: :::: :: *. : :.* :: : :** :: .. * :* . ::::. ..: .:*:: :* . : .. ..** . :.. :. : :.. * *: : . *: . : .* : . . :. * : ** . ... * : ::..: :: : .* : :. * :. :.*:* : .. .* ...*::*..*..* .* .. .: . . ::* ::: .**:******: ***:*** :**::***:*******:*:**:****:****:: :*::**.:**:*****::****::*.* *. ... .. .:*:* . *.:.:. : .. : ** * *... .** . * :: * *:*:*: :...** :: *:.:.. . : ** : * . .* ::. .*.:*.::*::*::* * :.*: * : . *.* :...**:: : :***.:* : **** .: .* * . **::****::.:* * :*:* :* ..*:: :: : ::* .: :* . *.* : . :**.*:*: .*.: : . .*. * ..* : * :: * ...: :. * *:. ..*.. . * :. * *. . . * :. :. . * ::.*. . . *.: . *:.* . *: . :.: .*. .* : * *. ** * .:. ", "identical_positions": 193, "similar_positions": 328, "identity": "18.47%" }, { "cls_id": "homologset.agr.RGD:620614", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXT6-1", "uniprot_id": "IL17B_MOUSE", "id": "Q9QXT6-1", "name": "Interleukin-17B", "aln": "---------MDWPHSL----LFLLAISIFLAPSHPRNTKGKRKGQGRPSPLAPGPHQVPLDLVSRVKPYARMEEYERNLGEMVAQLRNSSEPAKKKCEVNLQLWLSNKRSLSPWGYSINHDPSRIPADLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPQPPRPGPCRQRVVMETIAVGCTCIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L4E3-1", "uniprot_id": "A0ABK0L4E3_RAT", "id": "A0ABK0L4E3-1", "name": "Interleukin-17B", "aln": "MRCSFFSPTLVSTHFLSAKPLFLLAISIFLVPSQPRNTKGKRKGQGRPGPLAPGPHQVPLDLVSRVKPYARMEEYERNLGEMVAQLRNSSEPAKKKCEVNLQLWLSNKRSLSPWGYSINHDPSRIPEDLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPQPPRPGPCRQRVVMETIAVGCTCIF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UHF5-1", "uniprot_id": "IL17B_HUMAN", "id": "Q9UHF5-1", "name": "Interleukin-17B", "aln": "---------MDWPHNL----LFLLTISIFLGLGQPRSPKSKRKGQGRPGPLAPGPHQVPLDLVSRMKPYARMEEYERNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* * ****:***** .:**..*.********.****************:************: *********** *::*********:********************* ***************************************** ***.******.*************", "identical_positions": 155, "similar_positions": 16, "identity": "80.31%" }, { "cls_id": "homologset.agr.RGD:620615", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14863-1", "uniprot_id": "PO6F1_HUMAN", "id": "Q14863-1", "name": "POU domain, class 6, transcription factor 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPG--AGSETSLTVNEQ---------------VIVMSGHETIRVLEVGVDAQLPAEEESKGLEGVA---------------------------------------------------------------------------------------------------------AEGSQSGDPAEASQAAGEAGPDNLGSSAEATVKSPPGIPPSPATAIATFSQAPSQPQASQTLTPLAVQAAPQVLTQENLATVLTGVMVPAGAVTQPLLIPISIAGQVAGQQGLAVWTIPT------------------------------------------------------------ATVAALPGLTAASPTGGVFKPPLAG-------------LQAAAVLNTALPAPVQAAAPVQASSTAQPRPPAQPQTLFQTQPLLQTTPAILPQPTAATAAAPTPKPVDTPPQITVQPAGFA---------FSPGIISAASLGGQTQILG-----------------------------------------------SLTTAPVITSAIPSMPGISS------------------------------QILTNAQGQVIGTLPWVVN-----------------------------------------------------------------------------------------------------SASVA-----APAPAQSLQVQAVTP--------------------------------------QLLLNAQGQVIATLASSP---LPPPVAVR------------------------KPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIP--ITCSETPTVSQLVSKPHTPSLDE------DGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICR-------------------FEKLDITPKSAQKLKPVLEKWLNEAELRNQ----EGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQIP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07916-4", "uniprot_id": "PO6F1_MOUSE", "id": "Q07916-4", "name": "POU domain, class 6, transcription factor 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPG--AGSDSSLTVNEQ---------------VIVMSGHETIRVLEVGVDAQLPAEEESKGLESVA---------------------------------------------------------------------------------------------------------AGGSQSGGPVEASGPA-EAGSCDPDHSAEATVAAR----------------SPSESCPSDCHLQPSPEPASGITDPD-----------AAGCTSCP-------PGQVAGQQGLAVWTIPT------------------------------------------------------------ATVAALPGLTAASPTGGTFKPPLAG-------------LQAAAVLNTALPTPVQAAPPIQASSPAQPRPPAQPQPLFQTQPLLQTTPAILPQPTAATVAAPTPKTVDATPQITVQPAGFA---------FSPGIISAASLGGQTQILG-----------------------------------------------SLTTAPVITNTIPSMPGISS------------------------------QILTNAQGQVIGALPWVVN-----------------------------------------------------------------------------------------------------SASVA-----TPAPAQSLQVQAVTP--------------------------------------QLLLNAQGQVIATLASSP---LPQPVAVR------------------------KPNTPESPAKSEVQPIQPTQAVPQPAVILTSPTPALKPSAATPIP--ITCSETPTVSQLVSKPHTPSLDE------DGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICR-------------------FEKLDITPKSAQKLKPVLEKWLMEAELRNQ----EGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQIP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56223-1", "uniprot_id": "PO6F1_RAT", "id": "P56223-1", "name": "POU domain, class 6, transcription factor 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGISS------------------------------PILTNAQGQVIGALPWVVN-----------------------------------------------------------------------------------------------------SASVA-----TPAPAQSLQVQAVTP--------------------------------------QLLLNAQGQVIATLASSP---LPQPVAVR------------------------KPSTPESPAKSEVQPIQPTQAVPPPAVILTSPAPALKPSASAPIP--ITCSETPTVSQLVSKPHTPSLDE------DGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICR-------------------FEKLDITPKSAQKLKPVLEKWLNEAELRNQ----EGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQIP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31367-1", "uniprot_id": "PO6F1_DANRE", "id": "P31367-1", "name": "POU domain, class 6, transcription factor 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTEDLPANNAPLTVNEQLLGSCTLKFPAQDAQVIVMSGQETIRVLEVEVDTALS----SAGAAESG---------------------------------------------------------------------------------------------------------GDEEGSGQSLEATEEAQLDGPVTTSSTTAVTVEVS-----APVVQTVVSKAAISVSPAQQTSVPITVQACPQVLTQDGLASLMTGMLAQQSSLGQPLLIPLSMAGSVGGQGGLAVLTLPT------------------------------------------------------------ATVATLPGLAAASPAGGLLKLPFAG-------------LQAATVLN-----SVQTQLQAPAQAVLQPQMSAL-QAMQQTQTTAATTASIVQKASEPSVSVAT-----------LQTAGLS---------INPAIISAASLGAQPQFIS-----------------------------------------------SLTTTPIITSAMSNVAGLTS------------------------------QLITNAQGQVIGTLPLLVN-----------------------------------------------------------------------------------------------------PASLAGAAAASALPAQGLQVQTVAP--------------------------------------QLLLNSQGQIIATIGNGPTAAIPSTASVLP-----------------------KATVPLTLTKTTTQ--GPVGKVAPSKVIIAPQPSVVKPVTSLTAAGVIACGEMPTVGQLVNKP-SAVKDE------EAINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICR-------------------FEKLDITPKSAQKLKPVLERWLAEAELWNQ----KGQQNLMEFVGGEPSKKRKRRTSFTPQAIEVLNTYFEKNSLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKINVFQSQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4JD55-1", "uniprot_id": "A0A0B4JD55_DROME", "id": "A0A0B4JD55-1", "name": "", "aln": "MAEGCEDSAGAAESTTSQSQYTTLDKMLGTVLPCEAAIGATPGGGSSSGNSSSNIGGNTTNSSNNGSNIVKREFCDGSLMPGAGASVNNNNANAANNNNNNSSSSNNNNNNNNTKMQAMICNKSSSTNNSSSSSSSSSSCSSSSSSSSSATSTLTSCTTAAVVPSNCSTNANKSPVSPYSQSLGMAIGIGAGAGSSPLREASPLPSSRSPLNAIASTIAAKSPCSGAAPASPPSASSNSSSHVLALNIKTESDFDKEISCHKIHSPSSSSHAHSLHHHHHHHHHPHHSSRSNNNDDEMEITDGHALLSPPPPSHSHSHSPFDSKDHVKELEFYKNLAAKAASLANQHSPPPMPLPLPLPMQIDGEEDENEGEGEGEGEAEEQSAEVMRLRREEQAQAKAFAAHLNGTMQDMINLQKLQNLATLQQQQQQQQQHPHPHHGHQHHHHHPATAAALASLQGLAASVFNSPLNLSVGGEPVATTGPSVAPTSPTHNGGKSKTAKGGSSGNGSGGSSANSGTSSAQQQQQPDNPSSSSSPHHPLSASSLANVLAAATASPPPSLQAPPASAQMPQLILASGQLVQGVQGAQLLIPTAQGIAVQTILTIPVSPQIPTTEQFLPNAFGAFASYQQQQQQQQQQRDLLPPSLAALQHATALPQLAQTPTNLLKPNLFSTGVQQLLTALHPELFAAAAATHQQQQQQQQQQVQQQREREREREREREREREREREQHLGIGHLPHSHLAADLRRSAERSPTAGSPTGGSPGLAAKGPQPPPPGAAFLLQQQLHIKPETQTHLHHHLQTQSTSAVSSTLPQISLRHPDELTAPQMDLKPLELSASTSPPAPPPRHHFGHSLRGSSTVSPKHSPQGRMGGSGGSTTTGMNLSQHHERHDRLERLERQERHERRSHTPTATATRASVSSSSSAGHHGGSLPSGRLSPPSSAPSNSAANSISDRGYTSPLFRTHSPQGHALSLGGSPRLERDYLGNGPSSGTATSTSSCGAPTAAGSSATANVLSSINRLNASNGELTITKSLGAPTATATRASSASPRDDSPGPGPSTSSVSHMQPLKLSPSSRSEPPHLSPNGNDNDNDLLMDSPNEPTINQATTNVVDGIDLDEIKEFAKAFKLRRLSLGLTQTQVGQALSVTEGPAYSQSAICSSALAAQMYAAQLSTQQQNMFEKLDITPKSAQKIKPVLERWMKEAEESHWNRYKSGQNHLTDYIGVEPSKKRKRRTSFTPQALELLNAHFERNTHPSGTEITGLAHQLGYEREVIRIWFCNKRQALKNTVRMMSKGMV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*::: : *:: . * .:** : .:* : . *: *. : :* : * *. .. ** .. . :. .... : :.: . . . : . .* : . . .: . *:..* . :: :.*:*:**:**** **:****************:.************ *************:*****:*: *** : .**::* :::* ****************:* **::**:*. *:* *** :*::*.*:***:*:****:**:**** :: ", "identical_positions": 124, "similar_positions": 89, "identity": "9.6%" }, { "cls_id": "homologset.agr.RGD:620616", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CPQ1-1", "uniprot_id": "COX6C_MOUSE", "id": "Q9CPQ1-1", "name": "Cytochrome c oxidase subunit 6C", "aln": "MSSGALLPK--PQMRGLLAKRLRVHIAGAFIVALGVAAAYKFGVAEPRKKAYAEFYRNYDSMKDFEEMRKAGIFQSAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11951-1", "uniprot_id": "CX6C2_RAT", "id": "P11951-1", "name": "Cytochrome c oxidase subunit 6C-2", "aln": "MSSGALLPK--PQMRGLLAKRLRVHIVGAFVVALGVAAAYKFGVAEPRKKAYADFYRNYDSMKDFEEMRQAGVFQSAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09669-1", "uniprot_id": "COX6C_HUMAN", "id": "P09669-1", "name": "Cytochrome c oxidase subunit 6C", "aln": "MAP-EVLPK--PRMRGLLARRLRNHMAVAFVLSLGVAALYKFRVADQRKKAYADFYRNYDVMKDFEEMRKAGIFQSVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VMS1-1", "uniprot_id": "Q9VMS1_DROME", "id": "Q9VMS1-1", "name": "", "aln": "MANTPATSSAGPVLRGLHNATIKRNLAVSLGLTAVVTIAYKILVNDPKKAAYADFYSKYDANKSFERMKAAGRFQSC-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .. * :*** :: ::. :: :: *: **: * : :* ***:** :** *.**.*: ** *** ", "identical_positions": 26, "similar_positions": 22, "identity": "33.33%" }, { "cls_id": "homologset.agr.RGD:620617", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88791-1", "uniprot_id": "O88791_RAT", "id": "O88791-1", "name": "", "aln": "MSARGEGAGQPSTSAQGQPATPAPQKRGRGRPRKQPQEPTCEPSPKRPRGRPKGSKNKSPSKAAQKKAETIGEKRPRGRPRKWPQQIVQK-PAQET-EETSSQESAEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52927-1", "uniprot_id": "HMGA2_MOUSE", "id": "P52927-1", "name": "High mobility group protein HMGI-C", "aln": "MSARGEGAGQPSTSAQGQPAAPVPQKRGRGRPRKQQQEPTCEPSPKRPRGRPKGSKNKSPSKAAQKKAETIGEKRPRGRPRKWPQQVVQKKPAQET-EETSSQESAEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52926-1", "uniprot_id": "HMGA2_HUMAN", "id": "P52926-1", "name": "High mobility group protein HMGI-C", "aln": "MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKPAQEETEETSSQESAEED", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************:*.************ **** ****************************: ***************:*** **** ************", "identical_positions": 99, "similar_positions": 4, "identity": "90.83%" }, { "cls_id": "homologset.agr.RGD:620618", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53565-1", "uniprot_id": "CUX1_RAT", "id": "P53565-1", "name": "Homeobox protein cut-like 1", "aln": "----------------------------------------------------------------------------------MAANVGSMFQYWKRFDLQQLQRELDATATVLANRQD-------------ESEQSRKRLIEQSREFKKNTPEDLRKQVAPLLKSFQG----------------------------EIDALSKRSKEAEAAFLTVYKRLIDVPDPVPALDLG--------------------------QQLEIKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKSQAETIALEKEQKLQNDFAEKERK---------------------------LQETQMSTTSKLEEAEHKLQTLQTALEKTRTELFDLKTKYDEET--------------------------TAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQKAPDV--AIEVLTRSSLEVELAAK------------------------------------------EREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLNAKNSTLKQLEEKLKGQADYEDVKKELTTLKSMEFAPSEGAGTQDSTKPLEVLLLEKNRSLQSENATLRISNSDLSGSARRKGRDQPESRRPGPLPASPPPQLPRNTGEQVSNTNGTHHFSPAGLSQDFFSSNLASPSLPLASTGKFALNSLLQRQLMQSFYSKAMQEAGSTSTIFSTGPYSTNSISSPSPLQQS-------PDVNGMAPSPSQSESAGSISEG--------------------------------------------------------------------------EEIDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQR----------------------------------------------------GNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPVQASSTASSGNSDDAIRSILQQARREMEAQQAALDPALKPAPLSQPDLT--ILNPKLLS---ASPMSTVSTYPPLAIS------------LKKTPAAPEASTSALPSAPALKKEAQDAPTLDPPGSADATPGVLRPVKNELVRGSTWKDPWWNPVQPE-RRNLTTSEETKADETNASGKEK-----TGSSQPRAERSQLQGPSATAEYWKEWPNAESPYSQSSELSLTG---------ASRSETPQNSPLPSSPIVPMAKPAKPSVPPLTP--EQYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLN-------------------------------------GELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPTIETSKEGKPPEPSD-------------------------------PPTSDSQPTTP---------------------------LPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSD-SQPCEPPSVGIDYSQGASPQP---------QHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEELATQLNLKTSTVINWFHNYRSRIRREL------------------------------------------------------------FIEEIQAGSQGQAGASDSPSARSSR------------------------AAPSSEGDSCDGVEAADTEEPGGNIVATKSQGGPAEVTAAPADREEATQPAEKAKAQPLSSGTPGQDDGEDAGRSRPPPEGLADAPAPVPNLAAPAAGEDAATSATAPAMATEAPGAARAGPAERSSALPS--------------------------------------------------------------------TSAPANAPARRPSSLQSLFGLPEAAGARD---NPVRKKKAANLNSIIHRLEKAASREEPIEWEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53564-1", "uniprot_id": "CUX1_MOUSE", "id": "P53564-1", "name": "Homeobox protein cut-like 1", "aln": "----------------------------------------------------------------------------------MLCVAG-----------AKLKRELDATATVLANRQD-------------ESEQSRKRLIEQSREFKKNTPEDLRKQVAPLLKSFQG----------------------------EIDALSKRSKEAEAAFLTVYKRLIDVPDPVPALDVG--------------------------QQLEIKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKSQAETIALEKEQKLQNDFAEKERK---------------------------LQETQMSTTSKLEEAEHKLQTLQTALEKTRTELFDLKTKYDEET--------------------------TAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQKAPDV--AIEVLTRSSLEVELAAK------------------------------------------EREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLNAKNSTLKQLEEKLKGQADYEEVKKELNTLKSMEFAPSEGAGTQDSTKPLEVLLLEKNRSLQSENATLRISNSDLSGSARRKGRDQPESRRPGPLPASPPPQLPRNTGEQVSNTNGTHHFSPAGLSQDFFSSNLASPSLPLASTGKFALNSLLQRQLMQSFYSKAMQEAGSTSTIFSTGPYSTNSISSPSPLQQS-------PDVNGMAPSPSQSESAGSISEG--------------------------------------------------------------------------EEIDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQRENPGQSLNR------------------------------LFQEVPKRRNRSEGNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPVQTSSTSSSGNSDDAIRSILQQARREMEAQQAALDPALKPAPLSQPDLT--ILTPKHLS---ASPMSTVSTYPPLAIS------------LKKTPAAPETSTAALPSAPALKKEAQDVPTLDPPGSADAAQGVLRPMKSELVRGSTWKDPWWSPIQPE-RRNLTSSEETKADETTASGKER-----AGSSQPRAERSQLQGPSASAEYWKEWPSAESPYSQSSELSLTG---------ASRSETPQNSPLPSSPIVPMAKPAKPSVPPLTP--EQYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLN-------------------------------------GELGQGVLPVQGQQQGPVLHSVASLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPAIETSKEGKPPEPSD-------------------------------PPASDSQPTTP---------------------------LPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSD-SQPCEPPSVGIDYSQGASPQP---------QHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEELATQLNLKTSTVINWFHNYRSRIRREL------------------------------------------------------------FIEEIQAGSQGQAGASDSPSARSSR------------------------AAPSSEGDSCDGVEATDAEEPGGNIVATKSQGGLAEVAAAPADREEATQPAEKAKAQPLCSGTPGQDDGEDASRPRPLPEGLADAPAPVPSLAAPAAGEDAATSATAPATATEAPGAARAGPAERSSALPS--------------------------------------------------------------------TSAPANAPARRPSSLQSLFGLPEAAGARD---NPVRKKKAANLNSIIHRLEKAASREEPIEWEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39880-1", "uniprot_id": "CUX1_HUMAN", "id": "P39880-1", "name": "Homeobox protein cut-like 1", "aln": "----------------------------------------------------------------------------------MLCVAG-----------ARLKRELDATATVLANRQD-------------ESEQSRKRLIEQSREFKKNTPEDLRKQVAPLLKSFQG----------------------------EIDALSKRSKEAEAAFLNVYKRLIDVPDPVPALDLG--------------------------QQLQLKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLKNQAETIALEKEQKLQNDFAEKERK---------------------------LQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEET--------------------------TAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAK------------------------------------------EREIAQLVEDVQRLQASLTKLRENSASQISQLEQQLSAKNSTLKQLEEKLKGQADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKNRSLQSENAALRISNSDLSGSARRKGKDQPESRRPGSLPAPPPSQLPRNPGEQASNTNGTHQFSPAGLSQDFFSSSLASPSLPLASTGKFALNSLLQRQLMQSFYSKAMQEAGSTSMIFSTGPYSTNSISSQSPLQQS-------PDVNGMAPSPSQSESAGSVSEG--------------------------------------------------------------------------EEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARPKPWNKLTVRGKEPFHKMKQFLSDEQNILALRSIQGRQRENPGQSLNR------------------------------LFQEVPKRRNGSEGNITTRIRASETGSDEAIKSILEQAKRELQVQKTAEPAQPSSASGSGNSDDAIRSILQQARREMEAQQAALDPALKQAPLSQSDIT--ILTPKLLS---TSPMPTVSSYPPLAIS------------LKKPSAAPEAGASALPNPPALKKEAQDAPGLDPQGAADCAQGVLRQVKNEVGRSGAWKDHWWSAVQPE-RRNAASSEEAKAEETGG-GKEKGSGGSGGGSQPRAERSQLQGPSS-SEYWKEWPSAESPYSQSSELSLTG---------ASRSETPQNSPLPSSPIVPMSKPTKPSVPPLTP--EQYEVYMYQEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIRMQLWLN-------------------------------------GELGQGVLPVQGQQQGPVLHSVTSLQDPLQQGCVSSESTPKTSASCSPAPESPMSSSESVKSLTELVQQPCPPIEASKDSKPPEPSD-------------------------------PPASDSQPTTP---------------------------LPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSD-SQPCEPPSVGTEYSQGASPQP---------QHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRREL------------------------------------------------------------FIEEIQAGSQGQAGASDSPSARSGR------------------------AAPSSEGDSCDGVEATEGPGS-ADTEEPKSQG--------EAEREEVPRPAEQTEPPP--SGTPGPDDARDDDHEG----GPVEGPGPLP---SPASATATAAPAAPEDAATSAAAAPGEGPAAPSSAPPP--------------------------------------------------------------------SNSSSSSAPRRPSSLQSLFGLPEAAGARDSRDNPLRKKKAANLNSIIHRLEKAASREEPIEWEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10180-1", "uniprot_id": "CUT_DROME", "id": "P10180-1", "name": "Homeobox protein cut", "aln": "MQPTLPQAAGTADMDLTAVQSINDWFFKKEQIYLLAQFWQQRATLAEKEVNTLKEQLSTGNPDSNLNSENSDTAAAAATAAAVAAVVAGATATNDIEDEQQQQLQQTASGGILESDSDKLLNSSIVAAAITLQQQNGSNLLANTNTPSPSPPLLSAEQQQQLQSSLQQSGGVGGACLNPKLFFNHAQQMMMMEAAAAAAAAALQQQQQQQSPLHSPANEVAIPTEQPAATVATGAAAAAAAAATPIATGNVKSGSTTSNANHTNSNNSHQDEEELDDEEEDEEEDEDEDDEEENASMQSNADDMELDAQQETRTEPSATTQQQHQQQDTEDLEENKDAGEASLNVSNNHNTTDSNNSCSRKNNNGGNESEQHVASSAEDDDCANNNTNTSNNNNTSNTATSNTNNNNNNNSSSGNSEKRKKKNNNNNNGQPAVLLAAKDKEIKALLDELQRLRAQEQTHLVQIQRLEEHLEVKRQHIIRLEARLDKQQINEALAEATALSAAASTNNNNNSQSSDNNKKLNTAAERPMDASSNADLPESTKAPVPAEDDEEDEDQAMLVDSEEAEDKPEDSHHDDDEDEDEDREAVNATTTDSNELKIKKEQHSPLDLNVLSPNSAIAAAAAAAAAAACANDPNKFQALLIERTKALAAEALKNGAS-DALSEDAHHQQQQHHQQQHQHQQQHHQQQHLHQQHHHHLQQQPNSGSNSNPASNDHHHGHHLHGHGLLHPSSAHHLHHQTTESNSNSSTPTAAGNNNGSNNSSSNTNANSTAQLAASLASTLNGTKSLMQEDSNGLAAVAMAAHAQHAAALGPGFLPGLPAFQFAAAQVAAGGDGRGHYRFADSELQLPPGASMAGRLGESLIPKGDPMEAKLQEMLRYNMDKYANQALDTLHISRRVRELLSVHNIGQRLFAKYILGLSQGTVSELLSKPKPWDKLTEKGRDSYRKMHAWACDDNAVMLLKSLIPKKDSGLPQYAGRGAGGAGGDDSMSEDRIAHILSEASSLMKQSSVAQHREQERRSHGGEDSHSNEDSKSPPQSCTSPFFKVENQLKQHQHLNPEQAAAQQREREREQREREQQQRLRHDDQDKMARLYQELIARTPRETAFPSFLFSPSLFGGAAGMPGAASNAFPAMADENMRHVFEREIAKLQQHQQQQQAAQAQAQFPNFSSLMALQQQVLNGAQDLSLAAAAAKDIKLNGQRSSLEHSAGSSSCSKDGERDDAYPSSLHGRKSEGGGTPAPPAPPSGPGTGAGAPPTAAPPTGGASSNSAAPSPLSNSILPPALSSQGEEFAATASPLQRMASITNSLITQPPVTPHHSTPQRPTKAVLPPITQQQFDMFNNLNTEDIVRRVKEALSQYSISQRLFGESVLGLSQGSVSDLLARPKPWHMLTQKGREPFIRMKMFLEDENAVHKLVASQYKIAPEKLMRTGSYSGSPQMPQGLASKMQAASLPMQKMMSELKLQEPAQAQHLMQQMQAAAMSAAMQQQQVAQAQQQAQQAQQAQQHLQQQAQQHLQQQQHLAQQQHPHQQHHQAAAAAAALHHQSMLLTSPGLPPQHAISLPPSAGGAQPGGPGGNQGSSNPSNSEKKPMLMPVHGTNAMRSLHQHMSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELLSKPKPWHMLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMRLKQQVPHGPAGQDNPIPSRESTSATPFDPVQFRILLQQRLLELHKERMGMSGAPIPYPPYFAAAAILGRSLAGIPGAAAAAGAAAAAAAVGASGGDELQALNQAFKEQMSGLDLSMPTLKRERSDDYQDDLELEGGGHNLSDNESLEGQEPEDKTTDYEKVLHKSALAAAAAYMSNAVRSSRRKPAAPQWVNPAGAVTNPSAVVAAVAAAAAAAADNERIINGVCVMQASEYGRDDTDSNKPTDGGNDSDHEHAQLEIDQRFMEPEVHIKQEEDDDEEQSGSVNLDNEDNATSEQKLKVINEEKLRMVRVRRLSSTGGGSSEEMPAPLAPPPPPPAASSSIVSGESTTSSSSSSNTSSSTPAVTTAAAT-AAAGWNY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34237-1", "uniprot_id": "CASP_YEAST", "id": "P34237-1", "name": "Protein CASP", "aln": "---------------------------------------------------------------------------------MDTSVYSHALDIWAKADLTNLQRELDADVIEIKDKET-------------LSLNSRKSLATETKKFKKLEPEEKLNNVNKIIKQYQR----------------------------EIDNLTQRSKFSEKVLFDVYEKLSEAPDPQPLLQSS--------------------------LEKLGKIDDSKELKEKISYLEDKLAKYAD-----------YETLKSRLLDLEQSSAKTLAKRLTAKTQEINSTWEEKGRN---------------------------WKEREADLLKQLTNVQEQNKALEAKISKNIDIEGNGNEDGDQEN----------------------------NQKEVSTRIAEYNLVTQELETTQARIYQLEKRNEELSGALAKATSEAEKETELHAKELKLNQLES--------------------------------------------------ENALLSASYEQERKSTSHAINELKEQLNSVVAESESYKSELETVRRKLNNYSDYNKIKEELSALKKIEFGVNEDDSDND-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRSEDKNDNTFESSLLSANKKLQATLAEYRSKSTAQEEERNELKKSVDQLKQQIATLKEANEKLETDLEKVENVSPHFN---------------------------------------------------------------------------ETASMMSGVTRQMNN----------------------------------------------------------------------------RTSHKMSPTSSIIG---------IPEDGELSGNQSTILPIVTKQRDRFRSR-------------------NMDLEKQLRQGNSEK-------GKLKLEIS---------------KLKGDNTKLYERIRYLQS-----------------------------------------------------------------------YNNNNAPVNQSTERIDVESQYSRVYDESLHPMANFRQNELNHYKNKKLSALEK----------------------------------------------------------------------------------------------LFSSFAKVILQNKMTRMVFLFYCIGLHG------LVFMMSMYVINISG---------------------YMTPEVGIVQSAKSSSNLNGGLGGAEKVAAGVGSVHGINR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : * : . . . :. . * ::. . * :: : .. * : :.: : : . * * . : : :: : : . .: : . :: . .: ::: . . : *: . *: :* : .. : : : :: .:. : . :::. : .*:. : : : . :. . *.:: . : . * * : . :. . . . .: .: .. .: .: : :. * : : : . . . . : .. :: * : ..:.:*: :.:: . : . . :: : * * .. : . .. : :: : .. * * . .. . *:.. . . :: ::::: :: *: * :* *. .. : : *:: . . . . . .. : : * .: : : : . .. : . . :.: *:: : :* :** * . : :.:.* :. . : :. . .: : . . ", "identical_positions": 33, "similar_positions": 224, "identity": "1.52%" }, { "cls_id": "homologset.agr.RGD:620619", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFT1-1", "uniprot_id": "D3ZFT1_RAT", "id": "D3ZFT1-1", "name": "Replication factor C subunit 1", "aln": "--MDIRKFFGVISSGKKPVNETVKKNEKTKPSEGTVKGKKGVKEAKVNNPCKEDASRPKQHNKKKRIIYDSDSESEETVQVKNAKKKSEKLPVSCKPGKISRKDPVTYISETDEDDDFLCKKAASKSKENGVSTNSYLGASNVKKNEENTKTKSKPLSPIKLTPTSVLDYFGTESVQRSGKKMVASKKKESSQTPDDSRLNDEAIAKQLQLDEDAELERQLHEDEEFARTLALLDEEPKTKKARKDSEEGE-SFSPAKAELSKAAKQKSPA--NAEHFSIGRKTYSPAKYGKGRGSEGTKQPCRS-AHQKEACSSLKASSKLALMKAQEENSYKETELLAAKR-ESAIEPKGEKTTPRKTKGSPTKRESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLTFVITGVLESIEREEAKSLIERYGGKVTGNVSKKTSYLVMGRDSGQSKSDKAAALGTKILDEDGLLDLIRTMPG---------KKSKYEIAAEAEMKKEKSKLERTPQKNDQGKRKLSPTKRELEPKKSKLTPLKHSPRKAVKEEERVCPRGLDAKEPHGSHSA--------------SREECLLWVDKYKPTSLKNIIGQQGDQSCANKLLRWLRNWHKSSPEEKKHAAKFGKVASKDDGSSFKAALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKNSLKAIVAESLNNTSIKGFYTSGASPS--VSARHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIKSAMLSIAFKEGLKIPPPAMNEIILGANQDVRQVLHNLSMWCAQSKVLTYDQAKADSQRAKKDIRLGPFDVTRKVFAAGEETAHMS----LMDKSDLFFHDYSIAPLFVQENYLHVKPVAAGGDMKKHLMLLSRAADSICDGDLVDNQIRS-KQNWSLLPTQAIYASVVPGELMRGYMSQFPSFPSWLGKHSSTGKHDRTVQDLSLHMSLRTYSSKRTVNMDYLSHIRDALVRPLTSQGVEGVQRVVTLMDTYYLVKEDFDNIMEVSSWGGKP-STFSKLDPKVKAAFTRAYNKEAHLTPYSLQVVKASRPSIGPALDSEYNEESQEDA-------TQSDEKEQDALETDAMIKKKTRSSKPSKSEKEKESKKGKGKNSKK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35601-1", "uniprot_id": "RFC1_MOUSE", "id": "P35601-1", "name": "Replication factor C subunit 1", "aln": "--MDIRKFFGVISSGKKPVNETVK-NEKTKASEGTVKGKKGVKEAKVNNSGKEDASKPKQHSKKKRIIYDSDSESEETVQVKNAKKKSEKLSLSYKPGKVSQKDPVTYVSETDEDDDFVCKKAASKSKENGVSTNSYLGTSNVKKNEENVKTKNKPLSPIKLTPTSVLDYFGTESVQRSGKKMVTSKRKESSQNTEDSRLNDEAIAKQLQLDEDAELERQLHEDEEFARTLALLDEEPKIKKARKDSEEGEESFSSVQDDLSKAEKQKSPN--KAELFSTARKTYSPAKHGKGRASEDAKQPCKS-AHRKEACSSPKASAKLALMKAKEESSYNETELLAARRKESATEPKGEKTTPKKTKVSPTKRESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLTFVITGVLESIERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKILDEDGLLDLIRTMPG---------KRSKYEMAAEAEMKKEKSKLERTPQKNDQGKRKISPAKKESESKKCKLTLLKNSPMKAVKKEASTCPRGLDVKETHGNRSS--------------NKEECLLWVDKYKPASLKNIIGQQGDQSCANKLLRWLRNWHKSSPEEKKHAAKFGKLASKDDGSSFKAALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKNSLKAVVAESLNNTSIKGFYTSGAAPS--VSARHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIKSAMLSIAFKEGLKIPPPAMNEIILGANQDVRQVLHNLSMWCAQSKALTYDQAKADSQRAKKDIRLGPFDVTRKVFAAGEETAHMS----LMDKSDLFFHDYSIAPLFVQENYLHVKPVAAGGDMKKHLMLLSRAADSICDGDLVDNQIRS-KQNWSLLPTQAIYASVLPGELMRGYMTQFPSFPSWLGKHSSTGKHDRIVQDLSLHMSLRTYSSKRTVNMDYLSHIRDALVRPLTSQGVEGAQHVIKLMDTYYLMKEDFENIMEVSSWGGKP-SAFSKLDPKVKAAFTRAYNKEAHLTPYSLQVVKTSRLSTGPALDSEYSEEFQEDD-------TQS-EKEQDAVETDAMIKKKTRSSKPSKSEREKESKKGKGKNWKK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35251-1", "uniprot_id": "RFC1_HUMAN", "id": "P35251-1", "name": "Replication factor C subunit 1", "aln": "--MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPSKKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKKAASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKKMVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKKARKDTEAGE-TFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHSKSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSSPAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLESIERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIRTMPG---------KKSKYEIAVETEMKKE-SKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAKTIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSEDKKHAAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASS--VSTKHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIKGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAKKDIKMGPFDVARKVFAAGEETAHMS----LVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDMKKHLMLLSRAADSICDGDLVDSQIRS-KQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPSWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDVVALMDTYYLMKEDFENIMEISSWGGKP-SPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIKASRHSTSPSLDSEYNEELNEDD-------SQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKGKGKSSKK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35600-1", "uniprot_id": "RFC1_DROME", "id": "P35600-1", "name": "Replication factor C subunit 1", "aln": "MQRGIDSFFKRLP-------------AKAKSAEAE-----------------NGETPSKAPKRRKAVIISSDE--DEVVSPPETKKRKASKTAS------SEDDVVAATPEP------IAKKARNGQKP---------ALSKLKR---------------HVDPT---ELFG-----GETKRVIVPKPK-----------------------TKAVLE---FENEDIDRSLMEVDLDESIKEAAPEK----------------------------KVHSITRSSPSP--------------------------------------KRAKNSSPEPPKPKSTKSKATTPRVKKEKPAADLESSVLTDEE-----RHERKRASAVLYQKYKNRSSCLNPGSKEIPKGSPDCLSGLTFVVTGVLESMEREEAESVIKEYGGKVMTVVGKKLKYLVVGEEAGPKKLAVAEELNIPILSEDGLFDLIREKSGIAKQVKEEKKSPKKEHSSEEKGKKEVKTSRRSSDKKEKEATKLKYGEKH-DIAKHKVKEEHTSPKETKDKLNDVPAVTLKVKKEPSSQKEHPPSPR--TADLKTLDVVGMAWVDKHKPTSIKEIVGQAGAASNVTKLMNWLSKWYVN-HDGNKKPQRPNPWAKNDDGSFYKAALLSGPPGIGKTTTATLVVKELGFDAVEFNASDTRSKRLLKDEVSTLLSNKSLSGYFT-GQGQA--VSRKHVLIMDEVDGMAGNEDRGGMQELIALIKDSSIPIICMCNDRNHPKIRSLVNYCYDLRFQRPRLEQIKGKIMSICFKEKVKISPAKVEEIIAATNNDIRQSINHIALLSAKEDAS----QKSGQQVATKDLKLGPWEVVRKVFTA-DEHKHMS----FADKSDLFFHDYSLAPLFVQQNYLQVLPQ---GNKKDVLAKVAATADALSLGDLVEKRIRA-NSAWSLLPTQAFFSSVLPGEHMCGHFTGQINFPGWLGKNSKSGKRARLAQELHDHTRVCTSGSRLSVRLDYAPFLLDNIVRPLAKDGQEGVPAALDVMKDYHLLREDLDSLVELTSWPGKK-SPLDAVDGRVKAALTRSYNKEVMAYSYSAQAGIKKKKSEAAGADDDYLDEGPGEEDGAGGHLSSEEDEDKDNLELDSLIKAKKRTTTSKASGGSKKATSSTASKSKAKAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38630-1", "uniprot_id": "RFC1_YEAST", "id": "P38630-1", "name": "Replication factor C subunit 1", "aln": "-MVNISDFFGKNK----------------KSVRS------------------STSRPTRQVGSSKPEVIDLDTESDQESTNKTPKKMP-------------------------------------------------------------------------------------------------------------------------------------------VSNVIDVSETPEGEKK--------------------------------LPLPAKRKASSP---------------------------------------TVKPASSKKTKP-SSKSSDSASNITAQDVLDKIPSLDLSNVHVKENAKFDFKSANSNADPDEIVSEIG------SFPEGKPNCLLGLTIVFTGVLPTLERGASEALAKRYGARVTKSISSKTSVVVLGDEAGPKKLEKIKQLKIKAIDEEGFKQLIAGMPAE---------GGDGEAAEKARRKLEEQHNIATKEAELLVKKEEERSKKLAATRVSGGHLERDNVVREEDK----------------------------------------LWTVKYAPTNLQQVCGNKGS---VMKLKNWLANWENSKKNSFKHAGK-------DGSGVFRAAMLYGPPGIGKTTAAHLVAQELGYDILEQNASDVRSKTLLNAGVKNALDNMSVVGYFKHNEEAQNLNGKHFVIIMDEVDGMSGG-DRGGVGQLAQFCRKTSTPLILICNERNLPKMRPFDRVCLDIQFRRPDANSIKSRLMTIAIREKFKLDPNVIDRLIQTTRGDIRQVINLLSTISTTTKTINHENINEISKAWEKNIALKPFDIAHKMLDGQIYSDIGSRNFTLNDKIALYFDDFDFTPLMIQENYLSTRPSVLKPGQS-HLEAVAEAANCISLGDIVEKKIRSSEQLWSLLPLHAVLSSVYPASKVAGHMAGRINFTAWLGQNSKSAKYYRLLQEIHYHTRLGTSTDKIGLRLDYLPTFRKRLLDPFLKQGADAISSVIEVMDDYYLTKEDWDSIMEFFVGPDVTTAIIKKIPATVKSGFTRKYNSMTHPVAIYRTGSTIGGGGVGTSTSTPDFEDVVDADDNPVPADDEETQDSSTDLKKDKLIKQKAKPTKRKTATSKPGGSKKRKTKA------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* .** *. . . : * : . * :: .** .: :. . :: . *.: ** : * : : ::: .: . . : . :. . : * :. . . .:*:* :** ** :*.**** ::** :::: :.**.:* :..* . :*:* ::* .* * :.*:*: :** .. . * : : . * * . : : : : . :: : . . .: *. *: *:.:: : *: * . ** .** :* . : *:. : *... ::**:* ****:****:* ** :***:. :* ****.*** *: * *.* *: *::. . . :..:********:*. ****: :* : :.:. *:* :**:** **:*.: . * *::*:** :.**. :::*.::* .*: * ::.:* :. *:** :: :: .: .. : .: *:: : *:::.:*:: . * : ** *:*.*:.::**::*:**: . * . . * :: :*:.:. **:*:.:**: :. ***** :*. :** *.. : *::: .*..***::*.:.* * *:: * : * .: :.:** . : . :: *: .:* :. .: :*. *:* :** :.::*. . : :. : **:.:** **. . . . ... . :: .. :... :: * :** * :.:. . . . . .. ", "identical_positions": 185, "similar_positions": 301, "identity": "15.68%" }, { "cls_id": "homologset.agr.RGD:62062", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35821-1", "uniprot_id": "MBB1A_RAT", "id": "O35821-1", "name": "Myb-binding protein 1A", "aln": "MAEMKSPTKAEPASPAEAPQG-----DRRSLLEHSREFLDFFWDIAKPDQETRLRATEKLLEYLRTRPS----DSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFEDIQ-----------------LCDILGQIQEKYNLQAMNKAMMRPTLFANLFGVLALFQS--------------GRLVKDKEALMKCVRLLKILSHHYNHLQGQPVKALVDILSEVPESMFQEILPKVLKGDMKVILSSPKY-LELFLLARQRVP-----AELESLVGSVDLFSEDNIPSLVNILKVAANSVKKEQKLPDVALNLLRLALQENK-----FERFWKEVLEEGLLKKPSYTSSYMCFRLLGASLPLLSDEQ-LQLVMRGDLIRHFGEHMVVSKSQNP--LRFIPEISAYVGTFLEGCQDDPKRQFTVMVAFTAITNQGLPVMPTFWRVTRFLNTEALQNYVTWLRDMFLQPDLDSLVDFSTANQKRVQVASLNVPERTVFRLRKWIIHRLVSLVDHLHLEKDEAV--VEQIARFCLFHAFFKTKKATPQIPETKQHFSFPLEDGNRGVIVSAFFSLLQTLS-------------VKFRQTPDLAENGKPWTYRLVQLADMLLKHNR-NVANVTPLTAQQRQAWDQMMSTLKELEAQSSETR---AIAFQHLLLLVGLHLFKSPAESCDVLGDIQTCIKKSMEQNLRRSRSRAKASQEPVWVEVMVEILLSLLAQPSNLMRQVVRSVFGHVCSHLTPRGLQLILAVLNPETNEDEEDNVVVT-DTDEKQLKHGEDADSDSEDSKNSE------SDVDSEDGEESEE-------EDRD------KDVDPGFRQQLMEVLQAGNALG-GEE-EEEEELGDEAMMALDQNLASLFAEQKMRIQARHEEKNKLQKEKQLRRDFQIRALDLIEVLVTKQPEHPLILELLEPLLNIIQRSMRSRGSTKQEQDLLHKTARIFMH--HLCRARHYCHEVEPGAEALHAQVERLVQQAGNQADASVALYYFNASLYLLRVLKGNTTK-RYQDGQKLEGADIKSEPKDSEVQTTSCLDLDFVTRVYSASLESLLTKRNSPLTIPMFLDLFSRYPVICKNLLPIVVQHVAGSSRPRHQAQACLLLQKALSARELRVCFEDPEWE-QLISQVLGKTTQTLQTLGEAQSKGEHQRELSILELLNTVFRIVNHEKLSVDLTAFLGMLQGKQQKLQQNLQQGNHSSGSSRLYDLYWQAMNLLGVQRPKSEKKNVKDIPSDSQSPISTKRKKKGFLPETKKRKKLKSEGTTSEKKAASQQDAVTEGAMPAATGKDQPPSTGKKRRKRVKANTPSQVNGVTVAKSPAPNNPTLSPSTPPAKTPKVQKKKEKLSQVNGSTPVSPVEPESKK-HQKALSTKEVKRRS--SQSALPKKRARLSLVSRSPSLLQSGIRKRRVARRRVQTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPV4-1", "uniprot_id": "MBB1A_MOUSE", "id": "Q7TPV4-1", "name": "Myb-binding protein 1A", "aln": "MAEMKSPTKAEPATPAEAAQS-----DRHSLLEHSREFLDFFWDIAKPDQETRLRATEKLLEYLRTRPN----DSEMKYALKRLITGLGVGREAARPCYSLALAQLLQSFEDIP-----------------LCDILDQIQEKYSLQAMNKAMMRPSLFANLFGVLALFQS--------------GRLVKDKEALMKSVQLLKILSQHPNHLQGQPIKALVDILSEVPESMFQEILPKVLKGNMKVILRSPKY-LELFLLAKQRVP-----TKLESLMGSVDLFSEDNIPSLVNILKVAANSVKKEHKLPNVALDLLRLALKESR-----FELFWKKVLEEGLLKNPSWTSSYMCFRLLGASLPLLSEEQ-LQLVMRGDLIRHFGENMVISKPQNL--FKIIPEISTYVGTFLEGCQDDPKRQLTMMVAFTTITNQGLPVMPTFWRVTRFLNAEALQSYVAWLRDMFLQPDLNSLVDFSTANQKRAQDASLNVPERAVFRLRKWIIHRLVSLVDHLHLEKDEAV--VEQIARFCLFHAFFKTKKATPQIPETKQHFSFPLDDRNRGVFVSAFFSLLQTLS-------------VKFRQTPDLAENGKPWTYRLVQLADMLLNHNR-NVTSVTSLTTQQRQAWDQMMSTLKELEARSSETR---AIAFQHLLLLVGLHIFKSPAESCDVLGDIQTCIKKSMEQNPRRSRSRAKASQEPVWVEVMVEILLSLLAQPSNLMRQVVRSVFGHICPHLTPRCLQLILAVLSPVTNEDEDDNVVVTDDADEKQLQHGEDEDSDNEDNKNSE------SDMDSEDGEESEE-------EDRD------KDVDPGFRQQLMEVLKAGNALG-GVDNEEEEELGDEAMMALDQNLASLFKEQKMRIQARNEEKNKLQKEKKLRRDFQIRALDLIEVLVTKQPEHPLILELLEPLLNVIQHSMRSKGSTKQEQDLLHKTARIFMH--HLCRARRYCHEVGPCAEALHAQVERLVQQAGSQADASVALYYFNASLYLLRVLKGNTNK-RHQDGHKLHGADTE----DSEDQAANCLDLDFVTRVYSASLESLLTKRNSSLTVPMFLSLFSRYPVICKNLLPVLAQHVAGPSRPRHQAQACLMLQKTLSARELRVCFEDPEWE-QLITQLLGKATQTLQTLGEAQSKGEHQKELSILELLNTLLRTVNHEKLSVDLTAPLGVLQSKQQKLQQSLQQGNHSSGSNRLYDLYWQAMRMLGVQRPKSEKKNAKDIPSDTQSPVSTKRKKKGFLPETKKRKKLKSEGTTPEKNAASQQDAVTEGAMPAATGKDQPPSTGKKKRKRVKASTPSQVNGITGAKSPAPSNPTLSPSTP-AKTPKLQKKKEKLSQVNGATPVSPIEPESKKHHQEALSTKEVIRKSPHPQSALPKKRARLSLVSRSPSLLQSGVKKRRVASRRVQTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQG0-1", "uniprot_id": "MBB1A_HUMAN", "id": "Q9BQG0-1", "name": "Myb-binding protein 1A", "aln": "---MESRDPAQPMSPGEATQSGARPADRYGLLKHSREFLDFFWDIAKPEQETRLAATEKLLEYLRGRPK----GSEMKYALKRLITGLGVGRETARPCYSLALAQLLQSFEDLP-----------------LCSILQQIQEKYDLHQVKKAMLRPALFANLFGVLALFQS--------------GRLVKDQEALMKSVKLLQALAQYQNHLQEQPRKALVDILSEVSKATLQEILPEVLKADLNIILSSPEQ-LELFLLAQQKVP-----SKLKKLVGSVNLFSDENVPRLVNVLKMAASSVKKDRKLPAIALDLLRLALKEDK-----FPRFWKEVVEQGLLKMQFWPASYLCFRLLGAALPLLTKEQ-LHLVMQGDVIRHYGEHVCTAKLPKQ--FKFAPEMDDYVGTFLEGCQDDPERQLAVLVAFSSVTNQGLPVTPTFWRVVRFLSPPALQGYVAWLRAMFLQPDLDSLVDFSTNNQKKAQDSSLHMPERAVFRLRKWIIFRLVSIVDSLHLEMEEAL--TEQVARFCLFHSFFVTKKPTSQIPETKHPFSFPLENQAREAVSSAFFSLLQTLS-------------TQFKQAPGQTQGGQPWTYHLVQFADLLLNHSH-NVTTVTPFTAQQRQAWDRMLQTLKELEAHSAEAR---AAAFQHLLLLVGIHLLKSPAESCDLLGDIQTCIRKSLGEKPRRSRTKTIDPQEPPWVEVLVEILLALLAQPSHLMRQVARSVFGHICSHLTPRALQLILDVLNPETSEDENDRVVVTDDSDERRLKGAEDKSEEGEDNRSSE------SEEESE-GEESEE-------EERD------GDVDQGFREQLMTVLQAGKALG-GEDSENEEELGDEAMMALDQSLASLFAEQKLRIQARRDEKNKLQKEKALRRDFQIRVLDLVEVLVTKQPENALVLELLEPLLSIIRRSLRS-SSSKQEQDLLHKTARIFTH--HLCRARRYCHDLGERAGALHAQVERLVQQAGRQPDSPTALYHFNASLYLLRVLKGNTAEGCVHETQEKQKAGTDPSHMPTGPQAASCLDLNLVTRVYSTALSSFLTKRNSPLTVPMFLSLFSRHPVLCQSLLPILVQHITGPVRPRH--QACLLLQKTLSMREVRSCFEDPEWK-QLMGQVLAKVTENLRVLGEAQTKAQHQQALSSLELLNVLFRTCKHEKLTLDLTVLLGVLQGQQ----QSLQQGAHSTGSSRLHDLYWQAMKTLGVQRPKLEKKDAKEIPSATQSPISKKRKKKGFLPETKKRKKRKSEDGTP-----------AEDGTPAATGGSQPPSMGRKKRNRTKAKVPAQANGTPTTKSPAPGAPTRSPSTP-AKSPKLQKKNQKPSQVNG-APGSPTEPAGQKQHQKALPKKGVLGKS--PLSALARKKARLSLVIRSPSLLQSGAKKKAQVRKAGKP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRL5-1", "uniprot_id": "MBB1A_DANRE", "id": "Q6DRL5-1", "name": "Myb-binding protein 1A-like protein", "aln": "MVAVMQTDMGETENSAVRPKVT----DAKGILKQNRQFLDYFWDIAKPDRQIRLKAIEDLINYLKNSEQ----ADELKYTLKRLVDGLSHTREDARSGYSVALAQLLSVFEEIS-----------------LKSTLNSVKEKHNLLTASKKLIRNAVFGNFFGVLALSQS--------------TRLHKEPQVMLECVQLLQSLSEYREHLRDLPRKTMVDILSETSQDVFEEVLFSALQSDLTSALKSPEQ-LELLLVALQKFPSVLKPKKLKKLLGTTAVITKQNMPRLVEVLKTAARSVKKENILPAVALDLLQVSLREDN-----FEMFWTDAIITGMMSEMPGPTHYLSFRLLGASLPLLSIPQ-LQFVLSGDVMRQYGEHTMSAQMPDR--FKFAPEMAGYVGEFMQSCTD-PDKQLVVVLGFTQLTNQGNPVVPSYWKALENMHPSAVQRYVDWLIEAFCKPQLENCLDFSTRRQKGNQEAAVES-ESCVSRFRKWIIPRLTFIVENQQIKKQEAL--VMKVVRFIFFHAFFEVKKPTSEIPETTQALSVPINQQTRTAVVSGFYSLLQALNSMMVLGESVEVQGLNFRRIVGVQADGSMWIYSVFQFASMLLNQNK-YVKSLQSFSPEQRQGWDSVLESVEALRKKAKTASSPEHTAFQQLFLLIGIQMFTSPEESLDLLKDLQTCMEKAQAKKSK----KKKATDEPHWVEVIVEILLSLVSQPSRLVRSVCKTVFGRICPHLTQAALSSILNVLDPNKDEDESG-VVVTDDKKRKLKEEDEDDDDEEEDDDNDEGDDDDDDDDEEEGGEEGEESSDSSDDEEEDEAMEEGQEVDQNFRLELMKVLQGQNALATEEDGSDDEELDDAAMMKLDGSLASLFLEQRKKIQAKKDEKDRLNKEKGLVRDFKIKVLDMVEVFLSKQGFSPLVLGMVEPLLSVIENGMSS-ESSQPEQDYLRRVADIFRN--RLCRGKFYCKEIDGREAELHEMLERLIGRAQKLTDSSVALYYFSAALYVLKVLRGSVVD--------------------QELSTMGKVEVERATTCLKNALTSFMTKRKSPLTGAMFIDLFHRFPVLCVNLMDTALENITAGLRDHQQGQACFIMLKALQCKHVKNLMTGEQTT-ELYKKVVDQLTKSLENV-QCKNKTAHDKVVKALELCLHVVKIVLNQKMRVNLELLQDVL--------ASMNAEGCLEKTGKLEDTYWSVMRLFGVIKPKMEK--VKKVPEAEQTEETTK-KKKGFLPETKKRKNRKKPTILEG----------KETETPVEKTPEGASGEGKKNKNKKKNKKRKQQAGEETQDQPTPKKAKMQ-----QQQQQKQKKKKKKKGADGE--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39985-1", "uniprot_id": "DPO5_YEAST", "id": "P39985-1", "name": "rRNA processing protein POL5", "aln": "--------------------------------MTGKVNRDLFFKLASDLREERLHAAVALIKDLSALDLPD-DAEEWSYVLNRLIKGLSSDRNSARLGFSLCLTEVINLAVNMPPGQRPKGLESTNEFLSTLSTILNVNVNEGTKKSMKGKDERGILFGKLFGLKSLLNEPLFSEIFV-----KDLEKGNTEFFIRFTEQLIDLALKKNWIKEPCFFTLFQTMKMLLPFMDESSAEKILLIYDKYDLTLTNEGLSTYLLLKYEGDE----SLIPSVLDLKNPGWKDNDPLARGNLPLLTKVLRNSSVIPDANGGLKETKKQKNTNWNPRLHFVWSVLLPLFGNGKLENTSHISKKRKKTNNKKVQNSIQ-FPEFWKMAVDESFFNEKASSERKYLGFLIIDAAFKAVPGSYIGFCFSQNVMRTLINQSIDSQRVLNKISQLTLDSIVKACEEDSANRLVPCLNAMLFGPHGS--INFDKLTKSGTVSKLIAIKELPSTVLAQLLDVFFLQLQDKKGVLSHTLF--ALDSILHIVRAHKVEINDMDIMKPVLRPIVYMAFFKHTSDDLKLEQLHELAKER----------LYSILGELTINKEIRCKDPEINSWQYLTLKLILDI-ENSHVGDLINPLDENLENIKNEAISCLSKVCRSRTAQSWGLSTLLSMCLVQLYAGDTDSISVIEELCEFSKHENNSMVG-----------------ITEILLSLLAQKKALLRKLSLIIWQQFIEEVGLEELQILLDILKARENKQGFAQLFEGEEEFEEIKEENDASEDESKTGSESE------SESESDSDDADEK------------------DEEDEANEDILNIDKEATSALVKALNLPDNIVNDKGEVDLDQ------------LEGLSDDGGDDEDEESMDDEKMMELDDQLSEIFKRR----------KEALSSISTGNQRKFEVKQSRENVISFKHRVVD--MLAVYVKYCEKLT---------LANKSEHSNNLGGSLSKLVYF--IIPMLKCVN------------------------------------ETLDRPLADKISKLLKGKIFKIKVTAFKDMNKDIELMDLLKKTHKLMLTSKP----GQHAAVFYSMCSTSSLFLSKLYVEIGGN-DKLDELIDLYTATTKEWMQKGKCG-PNIFIDFINWLSSKKQTVMDKE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W5E4-1", "uniprot_id": "MBB1A_DROME", "id": "Q9W5E4-1", "name": "Myb-binding protein 1A", "aln": "--MKSKVDKPVTNGAPNATKTKAKEDRKRAKTQKSEADSQIPAKILKKSKKEKPAETEEKENTASNANLKVSQINKAVFVVFKKMQGSQLTKKMINSLITLLRDDTNAEQRTAT-----------------TGYVLKRLIRSTGADDMKTVSLAASYIHCILNAVPAIDAFEVLETLKRDLAVGSQQRGKEDSLAAVGQLVTAFCILQTPQFAKAEPKLVTAVFQILAAQLKG--REYLVSLCGDILAVSFKQLPAAIFEEYVWP------LLQPELNKPLSGLKVNTCDVLLAVHLTFSSVLGRENILASLWPKKPVYTQLFD-----LYFSGSTIHSDGVYARLASFLVNGGKDMLAAWQQYIDSKQPLKLNAAKACAIQVLSHVLLNFKPREEQLILDIFTPTCVQFLLHECSS---VKWDKGEGKKPSLKKLKEICFKFEGSLVLCYEKQFQNDDNKLHLLLKLLEHTLQLDSVISLPRFCQKLINQLSVESLHKLYDYYNNKLYSLEDEDRVSRVHCLNQMQLILNHSKLSQTAKWRQKQLNYLLLAGLFHLDASKKPCEAAQASAFSRQCAAR-----------CEEIFLGSLLHKCSGLPGLCQLLQKTLSYLNKELGQPDAESKLRSPRDESLQKAWKQVEKLLERPSKESDVVGQSFEALILFVSLALCTKIPPSITVLEDLIICRKNALQKSKE------QVNEELKWQDVLTDALLQLLLQTGHFWREFVQLVATALIPHLEHGNLEQVLEVLN--MNKNPLSKKSDGEEESDDELDKEESLKDSSDDSEDED------EDEEEDEGEDDAES--------------HLAQIRESVRQALVNDGDADDDGASSVDWNDVDEEQGERLNAALERSFQMFRPKSRKAQEKERPTKSERIDSTNLLHFRIRALDLLELFITKKPTQSVILDVLHCVFQVYSHCAADSKLQSLREASLKLLKKILARNIELKENQSTAPILEAIEQLMSSGEEHSEEDQENGKQPASRQAKRDIIIWRDRCFAYLVSQ----------------------ASADGEPKKSAVWPLLVEFLELWVAKRRSRLSLASFEALFQSGQWQGVAPLAVVLASHLDVQKTRSFRRAQILKLLSEQGRRLEVAFKDNNSSSKKFEKQIARYVN--QLETKASSSKELNLLLKILAQGGEKWQKLREQIQLVAKDLQ-----------------------------------------------------PNKKVAKQKKQAAAKPMVVEDEEST------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : .: . :: : : .: :.: : : * :: . :: : * .. . : ::. . : . : : . : :. :. : : . * * . * :. : :. . * : : : : : . * : .. : : : * . : . . : * : . :: : . : : : : . . .. . . . * * . : : : . : .:. *: : : : * :: :: .: . :.: ** *: * : *.. : . .: *. :* :*. .:: : . : ... . . ..: .: :.: .: . : : . :: . : . : . :. . :. * :. :..:: . :. . . : . * . : . . : : . . : : : :. . * : * : : . : . : : . . : . : :. : : .: ", "identical_positions": 25, "similar_positions": 204, "identity": "1.73%" }, { "cls_id": "homologset.agr.RGD:620620", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10252-1", "uniprot_id": "CD48_RAT", "id": "P10252-1", "name": "CD48 antigen", "aln": "MYFKKRRWFLILESLLLS---LVTGFQDQSVPNVN----------------AITGSNVTLTILKHPLASYQRLTWLHTTNQKILEYFPNGKKTVFESVFKDRVDLDKTNGALRIYNVSKEDRGDYYMRMLHET--EDQWKITMEVYDLVSKPAIKIEKTKNLTDSCHLRLSCKVEDQGVDYTWYEDSGPFPQRNPGYVLEITITPHNKSTFYTCQVSNPVSSENDTLYFIPPCT------LARSSGVHWIAAWLVVTLSIIPSILLA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18181-1", "uniprot_id": "CD48_MOUSE", "id": "P18181-1", "name": "CD48 antigen", "aln": "MCFIKQGWCLVLELLLLP---LGTGFQGHSIPDIN----------------ATTGSNVTLKIHKDPLGPYKRITWLHTKNQKILEYNYNSTKTIFESEFKGRVYLEENNGALHISNVRKEDKGTYYMRVLRET--ENELKITLEVFDPVPKPSIEINKTEASTDSCHLRLSCEVKDQHVDYTWYESSGPFPKKSPGYVLDLIVTPQNKSTFYTCQVSNPVSSKNDTVYFTLPCD------LARSSGVCWTATWLVVTTLIIHRILLT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09326-1", "uniprot_id": "CD48_HUMAN", "id": "P09326-1", "name": "CD48 antigen", "aln": "MCSRGWDSCLALELLLLPLSLLVTSIQGH-LVHMT----------------VVSGSNVTLNISESLPENYKQLTWFYTFDQKIVEWD-SRKSKYFESKFKGRVRLDPQSGALYISKVQKEDNSTYIMRVLKKTGNEQEWKIKLQVLDPVPKPVIKIEKIEDMDDNCYLKLSCVIPGESVNYTWYGDKRPFPKELQNSVLETTLMPHNYSRCYTCQVSNSVSSKNGTVCLSPPCT------LARSFGVEWIASWLVVTVPTILGLLLT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HYG0-1", "uniprot_id": "A0AC58HYG0_DANRE", "id": "A0AC58HYG0-1", "name": "", "aln": "MLTILIKNDSSFDKLTIVYPINKSQLFKWPMIHWKTQPLNFKWFSAEISVFVQTGDSVQLDLQTQPLPEFDYLSWINDKSENIVRYLHESKMIRYHLSYQNRIEFNETSFSLTLKNMQKADSGLYTARISGDL-MKDIAVYRVSVIDAVDSPVLTVNSTS--SDSCTVNFTCRAQHLIIDSSYQNNQ--CSPEEVTSQENYTLILSCSEELIICNYSNPVSWKKEEMEIKPLCSGNEQSLFSSAFPLFHMMLLTVISVAVIEFWGLIF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: * : : : : . . . :*..* * : :. ::*: .::*:.: . . :. ::.*: :: . :* : :: * * . * *: . :: :.* * * .* : ::. . *.* :.::* :: :: .. . . : : . *: **.** :: : : * :: : : *:: * * ", "identical_positions": 29, "similar_positions": 80, "identity": "10.82%" }, { "cls_id": "homologset.agr.RGD:620621", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07440-1", "uniprot_id": "B2LA1_MOUSE", "id": "Q07440-1", "name": "Bcl-2-related protein A1", "aln": "MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55179-1", "uniprot_id": "O55179_MOUSE", "id": "O55179-1", "name": "Bcl-2-related protein A1", "aln": "MSEYEFMYIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVGAYKQVSSFVAEFIMNNTGEWIRRNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V977-1", "uniprot_id": "G3V977_RAT", "id": "G3V977-1", "name": "Bcl-2-related protein A1", "aln": "MTDCEFMYIHSLAENYLQYVLQVPAFESAPSKTSRVLQRVAFSVQKEVEKNLKPYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVDTYKQVSSFVAEFIMNNTGEWIQQNGGWEDGFTKKFEPKSGWLTFLQMTGKIWEMLFLLKQHY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16548-1", "uniprot_id": "B2LA1_HUMAN", "id": "Q16548-1", "name": "Bcl-2-related protein A1", "aln": "MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: *: :*: **:.*** ***:* *.**::.****.**************. **:.:* *:**** :************************* *:*:*** ::*** ** :**::* **************::*****:** *********:***::**:* *** *** ", "identical_positions": 121, "similar_positions": 33, "identity": "69.14%" }, { "cls_id": "homologset.agr.RGD:620622", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70531-1", "uniprot_id": "S26A2_RAT", "id": "O70531-1", "name": "Sulfate transporter", "aln": "MSSENKEQHNLSPRDLPEEAYGFPPELPLGAQRGSSTDLRQFEPSDRRRAFRRIHMELHEKPDTNIRQLVMRKLQKSCQCNATKIRNRIFDFFPVLRWLPKYDLKKNILGDMMSGLIVGILLVPQSIAYSLLAGQEPIYGLYTSFFASIIYFLFGTSRHISVGIFGILCLMIGEVVDRELHKACPDIDTTSSSIAMFSNGCVVVN-----------------------HTLDGLCDKSCYAIKIGSTVTFMAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLSLPRSNGVGSVITTWIHIFRNIHKTNICDLITSLLCLLVLVPT-KELNEYFKSKLPAPIPTELIVVVAATLASHFGKLNENYNSSIAGQIPTGFMPPQAPDWSLIPNVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCITTSAALAKTLVKESTGCQTQLSAIVTSLVLLLVLLLIAPLFYSLQKCVLGVITIVNLRGALLKFRDLPKMWRLSRMDTVIWFVTMLSSALLSTEIGLLVGVCFSMFCVILRTQMPKISLLGLEEESE-IFESISTYKNLRSKSGIKVFRFIAPLYYINKECFKSALYKKT-LNPVLVKAAW----KKAAK-RKLKEETVTFHGDPDEVSMQLSHDPLELHTVVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPSVRDSLAKGEYCK--KEEENLLFYSLSEAVAFAEESQKEKGVCVVNGLSLSGD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62273-1", "uniprot_id": "S26A2_MOUSE", "id": "Q62273-1", "name": "Sulfate transporter", "aln": "MSSENKEQHDLSPRDLPEEAFGFPSELPLETQRRSGTDLRQSETGHGRRAFRRIHMELREKPDTDIKQFVIRELQKSCQCSAAKVRDGAFDFFPVLRWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPIYGLYTSFFASIIYFLFGTSRHISVGIFGILCLMIGEVVDRELHKACPDTDATSSSIAVFSSGCVVVN-----------------------HTLDGLCDKSCYAIKIGSTVTFMAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLSLPRSHGVGSVITTWIHIFRNIRNTNICDLITSLLCLLVLVPS-KELNEHFKDKLKAPIPVELIVVVAATLASHFGKLNGNYNSSIAGHIPTGFMPPKAPDWSLIPNVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCITTSAALAKTLVKESTGCQTQLSAIVTALVLLLVLLVIAPLFYSLQKCVLGVITIVNLRGALLKFRDLPKMWRLSRMDTVIWFVTMLSSALLSTEIGLLVGVCFSMFCVILRTQKPKNSLLGLEEESE-TFESISTYKNLRSKSGIKVFRFIAPLYYINKECFKSALYKKA-LNPVLVKAAW----KKAAK-RKLKEEMVTFRGDPDEVSMQLSHDPLEVHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAVGIQVLLAQCNPSVRDSLARGEYCK--KEEETLLFYSLSEAVAFAEDSQNQKGVCVVNGLSLSGD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50443-1", "uniprot_id": "S26A2_HUMAN", "id": "P50443-1", "name": "Sulfate transporter", "aln": "MSSESKEQHNVSPRDSAEGNDSYPSGIHLELQRESSTDFKQFETNDQCRPYHRILIERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLN-----------------------HTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLLPT-KELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVEESE-VFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQT-VNPILIKVAW----KKAAK-RKIKEKVVTLGGIQDEMSVQLSHDPLELHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCK--KEEENLLFYSVYEAMAFAEVSKNQKGVCVPNGLSLSSD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9I7-1", "uniprot_id": "E7F9I7_DANRE", "id": "E7F9I7-1", "name": "", "aln": "MPTEG-SCNNLSAEEDAK--------------REPNLPFR---------------LEECVKEKVSWKEALRKKVKK-CSCSTARVKSQIMKSFPIVKWLPRYRFKDWIIGDAMSGLIVGILLVPQSIAYSLLAGQDPIYGLYTSFFANIIYALLGTSRHISVGMFGVLCLLVGQVVDRELTLAGYSSDINQTTLGNVDN------------------------------STGPICDRSCYAIMVGATLTFTAGIYQVLMGLLQIGFVSVFLSDSLLSGFATGASLTILTSQIKYFLGLHLPRVQGWGSLIKTWISLFKNLGHTNLCDLITSLICLLVLVPA-KELNDRFKAKLKAPIPFELFVVIAATLASHFGHFKDTYGSDVAGTIPTGFMAPQSPNLSLVPNIAIDALSIAIVGFAITVSLSEMFAKKHGYIVNANQELNAIGNCNIISSYFHCFTVSAALTKTLVKESTGCHTQISGLVTALVLLLVMLVIAPAFYSLQKCVLAVIIVVNLRGALRKFGDIPQMWRVNRVDTVIWLLTMATSALVNTELGLLVGVVVSAFCVLGRTQFAQALQLGQAGDRE-LFEDIASYNGLQTQPDVAVFRYEAPIYYANQSLFKKSLYRNVGLDPLKEKAKQ----RKLEKQRKQKHSREDQKQEMDASTNVNLLQHSSFHTLVIDCSSVLFLDTAGVNALKEVFKDYKELGVNVLLAQCNTSVIDSLRRGDYYDPNKGTKDIQFHTIGEAILYGQSLKSQNGNCDTSV------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVM6-1", "uniprot_id": "Q9VVM6_DROME", "id": "Q9VVM6-1", "name": "", "aln": "MPSDKESPETKPLNNNNTNG------------NGGSVPSKPKIQPKYSIHRDVLTHEVVIKQTGYAARDKSIPSSLRNCWRSWNFFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYGILAGVSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHVVTAQLKDVLGISVPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMICNEILKPRLSKKCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSGLPEPVLPRLDLVPKVAVDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGKLEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRYSGSLNFATSLFFRRALYEAVGLDKIPLTKVSSSNSNSPSKGSKSSYSPVSQNGG-KAINGKLEETSGAFKVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGARLLLASPVDRVYDTLVHSMALS---EGPFEIFPTLHDCVEYANACRTA--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:: . . . .: . . : * * . . . . :*:::***:* : : ** ::*: *.*: :*:.:**.:*** .. *** :.*. : * ::***:***:* *.: .:: .:.** ::. .. . : . * :.::::: .*: :: *.::::* :* **:.*:.**.*.*: ::*:* * .**: :** :* .:* * * :::.: :**: :: .: : .:: : *: :. * *:* **.:*:..** *:: :: *. . .* **:*: * * .*:*.:*:*:::*:*: ::* :*:. ******* *..***: *:* *:: . * *:. :.:*:::::::.** :*::.:*:: ::::.:: *.* * ** :.**. : :* *: : : :: :: .::: . *: *: .::. ::***:*: .* :.: : . ** : : .: :.. . : :**: ..: : .. *: :**. . :: : . .. * * . . . . .:.:*:* * : .:*.** .:*.:: :: : * .:***. * *:* .. . * :: :.: :.: :. ", "identical_positions": 145, "similar_positions": 274, "identity": "18.78%" }, { "cls_id": "homologset.agr.RGD:620623", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVC8-1", "uniprot_id": "S26A3_MOUSE", "id": "Q9WVC8-1", "name": "Chloride anion exchanger", "aln": "-----------------MIEAIGNQYVVARPVYSTKT-FGEEFKKTHR---------HHKTFLDHLKGCCSCSSQKAKKIALSL--------------------FPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFA-LLVNIPPAYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMMVGVVVT-----------------------------------RVVSDPNASSELSSSSTENDSFIEEK---VMVAASVTVLSGIIQLLLGVLQVGFVVIYLSESLISGFTTAAAIHVLVSQLKFMLQLP------VPAYSDPFSIFKVLESVFTQIQKTNIADLVTSVIILVVVFVFKEIN-QRYRSKLPVPIPIELIMTVIATGVSYGCNFEDRFGVAVVGNMSLG----FQPPIT-PSVEVFQDTIGDSFGIAIVGFAVAFSVASVYSLKYDYPIDGNQELIALGVSNIFTGAFKGFAGSTALSRSGVQESTGGKTQVAGLLSAVIVLIVIVAIGFLLQPLQKSVLAALALGNLKGMLMQFAEIGRLWKKDK--YDCLIWIMTFIFAIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANVGRSN-IYKNKKNYA-----------EVYEPEGVKIFRCPSPIYFANIGFFKQKLIDAVGFSPLRILRKRNKALKKIRKLQKRGLIQMTPKGFICTSDGFKDSDEELDNNQIEELDQPINTTDLPFDIDWNGDLPLNITIPKISLHSLILDFSAVSFLDVSSMRGLRTILQEFIRIKVDVYIVGTDDDFIDKLARCEFFDDEVTDSIFFLTIHDAILHILMKKDYSTSKFNSSQEKERKFDFTINTNGGLRNRECQVPVETKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924C9-1", "uniprot_id": "S26A3_RAT", "id": "Q924C9-1", "name": "Chloride anion exchanger", "aln": "-----------------MIEAIGNQYVVARPVYSTKA-FGEEFKKTYG---------HHKTFLDHLKGCCSCSSQKAKKIALSL--------------------FPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFA-LLVNIPPAYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMMVGVVVT-----------------------------------RVASGSDTSPALSSSSAENDSMIEEK---VMVAASVTVLSGIIQLLLGVLQIGFVVIYLSESLISGFTTAAAIHVLVSQLKFMLQLT------VPAHSDPFSIFKVLESVFSQIQKTNIADLVTSVIILVVVFVVKEIN-QRYRSKLPVPIPIELIMTVIATGISYGCNFEQRFGVAVVGNMSLG----FQPPIT-PSVEVFQDTIGDCFGIAIVGFAVAFSVASVYSLKYDYPIDGNQELIALGVSNIFTGAFKGFAGSTALSRSGVQESTGGKTQVAGLLSAVIVLIVIVAIGFLLQPLQKSVLAALALGNLKGMLMQFAEIGRLWKKDK--YDCLIWIMTFIFAIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANVGRSN-IYKNKKNYA-----------DVYEPEGVKIFRCPSPIYFANIGFFKQKLIDAVGFNPLRILRKRNKALKKIRKLQKQGLIQVTPKGFICTSDGFKDSDEELDNNQIEELDQPINTTDLPFEIDWNADLPLNITIPKISLHSLILDFSAVSFLDISSMRGLRTILQEFIRIKVDVYIVGTDDDFIDKLARCEFFDDEVTDSIFFLTIHDAILHIWMKKDYSTSKFNSSQEKERKFDFTINTNGGLRNRECQVPVETKF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40879-1", "uniprot_id": "S26A3_HUMAN", "id": "P40879-1", "name": "Chloride anion exchanger", "aln": "-----------------MIEPFGNQYIVARPVYSTNA-FEENHKKTGR---------HHKTFLDHLKVCCSCSPQKAKRIVLSL--------------------FPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFA-LLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAV-------------------------------SKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLT------VPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEIN-QRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPG----FQPPIT-PDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDK--YDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTN-IYKNKKDYY-----------DMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHILMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0J5-1", "uniprot_id": "A0A8M9Q0J5_DANRE", "id": "A0A8M9Q0J5-1", "name": "", "aln": "------------------MQPFGRHYVVVRPLFSEDS-FAEQHERINR---------KRKTLRHHLKDYFSCDAKRAKNAALSL--------------------FPFIGWMKDYKIKEWLLGDIVSGISTGLVAVLQGLAFS-LLASLPPGYGLYTAFFPAIIYFFLGTSRHLSVGAFPILSLMVGAVVT-----------------------------------RLVPDEGPS--FNITGFEGLSLEQQR---VLVASSVTFLMGAFQLVMGLLQVGFIVMYLSETLVSGFTTAAAVHILVSQLRFVLGLD------FPGINGPLAIIYTLVEVFSRITSTNVADLVTSIAIMALVLIVKEIN-DRFKSKLPVPIPIEVIMTVIACGVSYAFNFEERFDVVIVGEMVNG----YESPVA-PNLEVIEETAVEAFPMAIVGFAVAFSVAKVYSVKHDYTIDGNQELIAFGVSNMFGASFRSFAASTALSRTAIQESTGGKTQIAGILSAMMVLIVIVGVGFLLEPLPRSVLGALVIVNLKGMLMQFSELPFLWRNDR--PDFVTWMVTFMASLFLGLDLGLAVGIGAELFTVVYRTQFPRCSVLANISGTD-LYRDRKDYTS---------IQIYEPDGVKIFKIPSPIFFANIDFFRDKLVQEVGFNPMRVLKKRNKALRKIRKMLCNGELEVSDRGPVLRQPSVDTSE-----GSMEDLDQPIDFSDLPIQVNWNSQLPANISVPPVNIHSLILDFCAVSFIDVSALKGLKATLKEFIRIEVDVYIVSCDVYIMEKLQHCTFFDDEIKTSIFYPTLHDAMLHILETHPDHG-----ELEKDININYEVIQRDSLTV-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVM6-1", "uniprot_id": "Q9VVM6_DROME", "id": "Q9VVM6-1", "name": "", "aln": "-------------------MPSDKESPETKPLNNNNT-NGNGGSVPSKPKIQPKYSIHRDVLTHEVVIKQTGYAARDKSIPSSLRN----CWRSWNFFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYG-ILAGVSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHVVTAQLKDVLGIS------VPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMICNEILKPRLSKKCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSG----LPEPVL-PRLDLVPKVAVDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGK--LEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHR-----------NAMQVPEVRIFRYSGSLNFATSLFFRRALYEAVGLDKIPLTKVSSSNSNSPSKGSKSSYSPVSQNG--------------------------------------GKAINGKLEETSGAFKVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGARLLLASPVDRVYDTLVHSMALSEGP--FEIFPTLHDCVEYANACRTA--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53394-1", "uniprot_id": "SULX_YEAST", "id": "P53394-1", "name": "Putative sulfate transporter YPR003C", "aln": "MTSNNSLLGRGRMSYSSTAPPRFKRSVDQRDTFSDNFDYDKDSSNRGRTYIAASNSTTGVPPPNNSRSGCTNNTNNTNNTSNTSNTNNNDSVDENTVFETLPYYLPCFSWLPEYTFN-KLWGDVIAGISVASFQIPLALSYTTSIAHVPPLCGLYSLAISPFVYGILGSVPQMIVGPESAISLVVGQAVES-----------------------------------------------------ITLHKENVSLIDISTVITFVSGTILLFSGISRFGFLGNVLSKALLRGFISSVGLVMIINSLISELKLDKFLVSLPQHYHTPFEKILFLIDYAPAQYHIPTAIFSGCCLIVLFLTRLLKRKLMKYH-KSAIFFPDILLVVIVTILISMKFNLKHRYGISIIGDFSMDNFDELKNPLTRPRRKLIPDLFSASLIVAMLGFFESTTASKSLGTTYNLTVSSNRELVALGFMNIVISLFGALPAFGGYGRSKINALSGAQSVMSGVFMGVITLITMNLLLQFVHYIPNCVLSVITTIIGISLLEEVPGDIKFHLRCGGFSELFVFAVTFCTTIFYSIEAGICIGCVYSIINIIKHSAKSRIQILARVAGTS-NFTNLDDYMMNMKRNSLDVEGTEEIEGCMIVRIPEPLTFTNSEDLKQRLDRIERYGSSKIHPGR----KSLRSKDSIKYVIFDLGG----------------------------------------MTSIDSSAAQVLEEIITSYKRRNVFIYLVNVSINDKVRRRLFKAGVAASVERAQANNNENNTSNTFSDAGETYSPYFDSIDAALYEIEKMKIKGNNVPNNDSESFMSNTLFNSSLV---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. : . . : . .. : . . : : :* *: * . * .*:::*::.. . : .::: :. :.. *** :. : * ::*: :: :*. . *::.. .* :: : : :: ::. * . * .. :.* : **:.*: ** ::.. :: .* : : .. : : . . : . :: .: : : * . :* .::.: :* :: : : :*.: . *: * . . . .: :*:: : : . . .:. : *:**.*:*. *:. . * :. . .*: :: :*. : ::.:. . :.::.: : :. : ..**. : :: : : . : . : ** :. .: *: . .:: : : . *. : : : : .:: : *.: . .: *:. :: * . : .. . . * . . . : .: : :.: . : :. . : ::. .: : ", "identical_positions": 49, "similar_positions": 230, "identity": "5.64%" }, { "cls_id": "homologset.agr.RGD:620624", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55043-1", "uniprot_id": "ARHG7_RAT", "id": "O55043-1", "name": "Rho guanine nucleotide exchange factor 7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDNANSQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYVREIKPSEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETEHEYSKELQSVLSTYLWPLQTSEKLSSANTSYLMGNLEEISSFQQVLVQSLEECTKSPEAQQRVGGCFLSLMPQMRTLYLAYCANHPSAVSVLTEHSEDLGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHPDRQDIQKSMTAFKNLSAQCQEVRKRKELELQILTEPIRSWEGDDIKTLGSVTYMSQVTIQCAGSEEKNERYLLLFPNLLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLHEWVEHLQRQTKVTSVSNPTIKP----------------------------------HSVPSHTLPSHPLTPSSKHADSKPVALTPAYHT---------------------------------------------------------------------------------------------------------------LPHPSHHGTPHTTISWGPLEPPKTPKPWSLSCLR---------------------------------------------PAPPLRPSAALCYKEDLSRSPKTMKKLLP----------------------KRKPERKPSDEEFAVRKSTAALEEDAQILKVIEAYCTSAKTRQTLN---------------------------------------------------------------------------SSSRKESAPQVLLPEEEKIIVEETKSNGQTVIEEK--------------------------------------------------------------------------------------------------------SLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETNL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES28-1", "uniprot_id": "ARHG7_MOUSE", "id": "Q9ES28-1", "name": "Rho guanine nucleotide exchange factor 7", "aln": "MNSAEQTVTWLITLGVLESPKKTISDPEVFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRNESECLSNIREFLRACGASLRLE---------------------TFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPS-SHRIKSFDSLGSQSSHSRTSKLLQSQYRSLDMTDNTNSQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYVREIKPSEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETEHEYSKELQSVLSTYLRPLQTSDKLSSANTSYLMGNLEEISSFQQVLVQSLEECTKSPEAQQRVGGCFLSLMPQMRTLYLAYCANHPSAVSVLTEHSEDLGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHPDRQDIQKSMTAFKNLSAQCQEVRKRKELELQILTEPIRSWEGDDIKTLGSVTYMSQVTIQCAGSEEKNERYLLLFPNLLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCTSQQDLHEWVEHLQKQTKVTSVSNPTIKP----------------------------------HSVPSHTLPSHPLTPSSKHADSKPVALTPAYHT---------------------------------------------------------------------------------------------------------------LPHPSHHGTPHTTISWGPLEPPKTPKPWSLSCLR---------------------------------------------PAPPLRPSAALCYKEDLSKSPKTMKKLLP----------------------KRKPERKPSDEEFAVRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSTWQGTDLMHNHVLADDDQSSLDSLGRRSSLSRLEP----------------SDLSEDSEYDSIWTAHSYRMGSASRSRKESAPQVLLPEEEKIIVEETKSNGQTVIEEK--------------------------------------------------------------------------------------------------------SLVDTVYALKDEVQELRQDNKKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETNL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14155-4", "uniprot_id": "ARHG7_HUMAN", "id": "Q14155-4", "name": "Rho guanine nucleotide exchange factor 7", "aln": "MNSAEQTVTWLITLGVLESPKKTISDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASLRLELLFPPSQPPQHLVTTILLSASTFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPS-SHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKP----------------------------------HSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHT---------------------------------------------------------------------------------------------------------------LPHPSHHGTPHTTINWGPLEPPKTPKPWSLSCLR---------------------------------------------PAPPLRPSAALCYKEDLSKSPKTMKKLLP----------------------KRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLN---------------------------------------------------------------------------------STWQGTDLMHNHVLADDDQPSLDSLGRRS--------------------------------------------------------------------------------------------------------SLS------RLEPSDLSEDSDYDSIWTAHSYRMGSTSRKSCCSYISHQN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEZ3-1", "uniprot_id": "A0A8M2BEZ3_DANRE", "id": "A0A8M2BEZ3-1", "name": "", "aln": "MNPAEQTVTWLITLGVLESPKKTISDPDGFLQASLKDGVVLCRLLERLRPGTTDKIIQDPKNDSECLSNITEFLKGC-AVFRVEP---------------------FEAGDLLQGHNISRVLTTLVALNKVTADIGIGSDSVCTRHSSAHRIKSFESLASQSSLGRSSKLLHNQFRSLDMTDNSNAQLVVKARFNFQQTNEDELTFSKGDLISVTRTEEGGWWEGILNGKTGWFPSNYVKEVKGSDKQVSPKSGNLKSPPKGFDTASISKTYYNLVLQNILETETEYSRELQNLLTSYLRPLQMTERLSPADVSVILGNLEEISTFQQTLVQSLEDLTKLPELQQKVGGFFLNLMPQMRSLNVSYCSNHPSTVNVLTVHSEELGEFMEARGASVPGILTLTSGLSKPFMRLDRYPTLLKELERHMEEGHPDRTEIQKCMTAFKNLSAQCQEVRKRKELELQILAETIRLWEGEDIKTLGSVLYMSQAMVQNHGCEEKNERYLLLFPHVLLILSASPRMSGFIYQGKLPLSGMTVTPLEDCESHKDAFELSGSMFERLQVICYNKQDLHDWLEHLNRQTKHTTMAAPSMKP----------------------------------LTVPCHTLPSHPLTP-SRHGESRGLTVAPAYHT---------------------------------------------------------------------------------------------------------------LPHPSSHGTPHSTMMWGPLEPPKTQKPWSLSCLR---------------------------------------------PAPPLRPSAALCYKEDLSKSPKTMKKLLP----------------------KRKPERKPSDEEFALRKSTVALEEDAQILKVIEAYCTSAKTRQTLN---------------------------------------------------------------------------SRQWKDGSPALIVPGDEKFSVDELKSNGQTLLEEK--------------------------------------------------------------------------------------------------------SLVDVVYALRDEVQELKQDYKKMKKSLEEEQRARKDLERIVKKMLKNMNDPSWDETNL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DZ19-1", "uniprot_id": "A8DZ19_DROME", "id": "A8DZ19-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDQPLVVQAEYSFMGSNNDELCFQKGDVITVTQREDGGWWEGTLNDKTGWFPSNYVNECKVQ----LPLTETIRPPEE-------IQEYRSVVLKDLLDSERAHVAELQGLLENFLEPMQQTQILSQDEYAQLMCNFVEIVRTHEDLLIQIEECN------DRVGKLFLTSAPLMKKVHQAYCAAHPKAIVILDKYKDELEKYMERQGAATPGLLVLTTGLSKPFRRLDKYSAMLQELERHMESSHPDRGDTQRSVAVYKDIAATCSATRRQKELELQVLTGPVRGWQGQELSTLGDIIHMGSVAVG----ADHRDRYFVLFPQTLLFLSVSQRMSAFIYEGKLPLTGIIVNRLEDTDALKNAFEISSPLIDRIVAVCQGPNEANKWVELLNANNPSLPMGIKRQLSNLSNSSLGHLNAAHLSQHLDSRGYCTRFSLCAYYSSPPCHVRPLRVTLPPSNYPATAPYANLSAHFARLVKGGGLRSAIVKMLLYPQARQSIDLKRIALRKRRCHKASAKLKDLNTNQDSGQSELERQDAIELPTDSESYDDDFEDDFLHSCDSDPFEYVQFYQNKRNDSMCNSTGTFVDHGTGARRHCSSINLIKLDSADTDEVLALNELKKESLVIGSRALRALARKSTTRNSSVHTSTATLELGVGGSITNCVEEEPILKVKPSFSLQQQSSDASSIFAARLGGAFTACENLASMPDDLSRESSIQEPPTPLPASPTERHSMPTIFVGNRFNHSKNTEVYVPTWRDRQEMQNQSVDAKQDEELHSSSIDLPAACLSAPDKLQAELLYNYDEILEKPLQLHRELTPFPGHNLNSDKRVSHKSDSPSTGNAKTDPNLATRSSSTTELCIDTTSKKRTTPSERSRDSIRRCISYQFLQMSNRPPPPPPPRRDPDLHLDTKCRCCENSQCPSPRSSDSGMAGSCTITSPDPPNPESYFPMEAAGHDMLDNVEPERFDVCGMFREKFLTPEATQDVVDLSEEQPQLSDEPTTPTNRKEEPTCITSAQVQVNTRSIFLPSSSSMDETNRNVPANNILFSSSSADQLEPQATFRSGMYAHWWKKERLPPEVVRGIAHAYNKSLPSKDSKDSGSVCSSCFCSLGASGYSEGALYCSVCQNCADYYNGSVTSTTNTTTTTSSASCPLCSEDEGMIAPTHDSSSLDCPICNGRIASGAEEGKQSEMDRRPDVAAIKPHTPTARRPSASHSQQHPGRQQQRREPQPPGVSGHQLDVASQTEPVVQPPSQLQSVHAHSASTTSSASTTTTKSAKSSGGIRPQIKFSPDTKQQDSSSTPGVIHGRQSSNSGSGSSSGGSGGNGGAKRKERKHKG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***:*.:.* :*:*** *.***:* **: *:****** *.:*********.* * . * : .::.* : : * .:**:::*::* : *** :* .:* *:* :: ** : : :: *: ** :: *: .:*: . ::** **. * *:.: :**: **.:: :* :.::* ::** :**: **:*.**:****** ***:*.::*:*******. *.** : *:.::.:*:::* *. .*::******:*: .:* *:*:::.***.: :*... : ::.:**::***: **:**.* ***.***:**** :*: :. *** : ::***:*..:::*: . * . :: :.*:* *: :. .:. . : *.*. * : * *.: : . .*:.: : * : ::: *:...* : :*. *: * *: ..::. ::: * :.. : * :. * *:. .* : : : * *.* .: : ** :: .. : . . : ... . * :* :: . . . : : . ", "identical_positions": 175, "similar_positions": 218, "identity": "11.56%" }, { "cls_id": "homologset.agr.RGD:620625", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BFV3-1", "uniprot_id": "DUS4_MOUSE", "id": "Q8BFV3-1", "name": "Dual specificity protein phosphatase 4", "aln": "------MVTMEELREMDCS--VLKRLMNRDENGGGG---------SAGGNGSGSHGALGLLSGG-KCLLLDCRPFLAHSAGYIRGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFS---SEYPEFCSKTKALAAIPPPVPPSTN----------ESLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPN-----HFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLTTSCAAEAASPSGPLR------ERGKATPTPTSQFVFSFPVSVGVHAAPSNLPYLHSPITTSPSC--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62767-1", "uniprot_id": "DUS4_RAT", "id": "Q62767-1", "name": "Dual specificity protein phosphatase 4", "aln": "------MVTMEELREMDCS--VLKRLMNRDENGG-----------TAGSSG-GSHGALGLLSGG-KCLLLDCRPFLAHSAGYIRGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFS---SEYPEFCSKTKALAAIPPPVPPSTN----------ESLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPN-----HFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLTTSCAAEAASPSGPLR------ERGKATPTPTSQFVFSFPVSVGVHAAPSNLPYLHSPITTSPSC--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13115-1", "uniprot_id": "DUS4_HUMAN", "id": "Q13115-1", "name": "Dual specificity protein phosphatase 4", "aln": "------MVTMEELREMDCS--VLKRLMNRDENGG-------------GAGGSGSHGTLGLPSGG-KCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFS---SEYPEFCSKTKALAAIPPPVPPSAT----------EPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPN-----HFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLR------ERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38590-1", "uniprot_id": "MSG5_YEAST", "id": "P38590-1", "name": "Tyrosine-protein phosphatase MSG5", "aln": "MQFHSDKQHLDSKTDIDFKPNSPRSLQNRNTKNLSLDIAALHPLMEFSSPSQDVPGSVKFPSPTPLNLFMKPKPIVLEKCPPKVSPRPTPPSLSMRRSEASIYTLPTSLKNRTVSPSVYTKSSTVSSISKLSSSSPLSSFSEKPHLN-RVHSLSVKTKDLKLKGIRGRSQTISGLETSTPISSTREGTLDSTDVNRFSNQKNMQTTLIFPEEDSDLNIDMVHAEIYQRTVYLDGPLLVLPPNLYLYSEPKLEDILSFDLVINVAKEIPNLEFLIPPEMAHKIKYYHIEWTHTSKIVKDLSRLTRIIHTAHSQGKKILVHCQCGVSRSASLIVAYIMRYYGLSLNDAYNKLKGVAKDISPNMGLIFQLMEWGTMLSKNSPGEEGETVHMPEEDDIGNNEVSSTTKSYSSASFRSFPMVTNLSSSPNDSSVNSSEVTPRTPATLTGARTALATERGEDDEHCKSLSQPADSLEASVDNESISTAPEQMMFLP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. ::* . : * **: :. .. . . *:: : * *::. :*:: ... .. . . :** . :* * . : .. : * . *. .*: *.. :. *::* ::: .: ::* : :* :. * .:: :* : .. . * **. . : :::: :: :: . * :. .: * *.: ::**:.: ** * :: * :* .*.:.* . : . . *.:.:. ::*****.*:****:: :**:* : *::*:: :* . ****:.:: **::: : : .* . *. : * . * ..:. : :* . ***: ..: ::*.. . * :*. ... ", "identical_positions": 71, "similar_positions": 156, "identity": "14.49%" }, { "cls_id": "homologset.agr.RGD:620626", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09630-1", "uniprot_id": "HXC6_HUMAN", "id": "P09630-1", "name": "Homeobox protein Hox-C6", "aln": "------------------------------------MNSYFTNPS------------LSCHLAGGQDVLPNVALN----------------------------------------------------STAYDPVRHFSTYGAAVAQN-------RIYSTPFYSPQENVVFSSSRGPYDYGSNSFYQEKDMLSNCRQNTLGHNTQTSIAQDFSSEQGRTAPQDQKAS-IQIYPWMQ-----RMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGG----------GATADSLGG----------------------------------KEEK-REETEEEKQKE-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10629-1", "uniprot_id": "HXC6_MOUSE", "id": "P10629-1", "name": "Homeobox protein Hox-C6", "aln": "------------------------------------MNSYFTNPS------------LSCHLAGGQDVLPNVALN----------------------------------------------------STAYDPVRHFSTYGAAVAQN-------RIYSTPFYSPQENVVFSSSRGPYDYGSNSFYQEKDMLSNCRQNTLGHNTQTSIAQDFSSEQGRTAPQDQKAS-IQIYPWMQ-----RMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGG----------GATADSLGG----------------------------------KEEK-REETEEEKQKE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15862-1", "uniprot_id": "HXC6A_DANRE", "id": "P15862-1", "name": "Homeobox protein Hox-C6a", "aln": "------------------------------------MNSYFANPS------------LSCHLSGGQEVLPNMPLN----------------------------------------------------STTYDSVRHFSSYGTTVTQN-------RIYASPFYSPQDNVVFGSSRGPYEYGSNVFLQDKDVLPSCRQTSMGLNAQSHVAQEYNLEQARAGTQDQKANNIQIYPWMQ-----RMNSHSGVGYGSDRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKETNLTSTVPG----------------TESAGT----------------------------------PQET-EKETEEEPKKKD----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9PWM5-1", "uniprot_id": "HXC6B_DANRE", "id": "Q9PWM5-1", "name": "Homeobox protein Hox-C6b", "aln": "------------------------------------MNSYFTNPS------------LSCHLNSGQEVLPSVAIS----------------------------------------------------STNYDPVRHFSPYGAAVAQN-------RIYSNPFYSHQENVMFGSSR-PYDYGSNMFYQDKDVLPSCRQG-FG-QTQGSLTQDYASDQGKTVEPK---GVVQIYPWMQ-----RMNSHR-VGYGSDRRRGRQIYSRYQTLELEKEFHYNRYLTRRRRIEIANTLCLSERQIKIWFQNRRMKWKKESNLTSILND----------------NGSVGA----------------------------------GQDTDKEETGETAEKDEHD--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18865-1", "uniprot_id": "HXC4_RAT", "id": "P18865-1", "name": "Homeobox protein Hox-C4", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------LVVMLESR--------------------------------------------------------FP------------------GPARGVAN---CRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHDSPTPK-------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02835-1", "uniprot_id": "FTZ_DROME", "id": "P02835-1", "name": "Segmentation protein fushi tarazu", "aln": "MATTNSQSHYSYADNMNMYNMYHPHSLPPTYYDNSGSNAYYQNTSNYQGYYPQESYSESCYYYNNQEQVTTQTVPPVQPTTPPPKATKRKAEDDAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAPAVSTKVTASPAPSYDQEYVTVPTPSASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPVPMYHHHQTTAAYPAYSHSHSHGYGLLNDYPQQQTHQQYDAYPQQYQHQCSYQQHPQDLYHLS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * . * *.********:***:******:**::*.*:************** **: : ", "identical_positions": 41, "similar_positions": 12, "identity": "10.0%" }, { "cls_id": "homologset.agr.RGD:620627", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63064-1", "uniprot_id": "CD52_RAT", "id": "Q63064-1", "name": "CAMPATH-1 antigen", "aln": "MNTFL-LLLTISLLVVVQIQTGDLGQNSTAVTTPANKAATTAAATTKAAATTATKTTTAVRKTPGKPPKAGASSITDVGACTFLFFANTLMCLFYLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64389-1", "uniprot_id": "CD52_MOUSE", "id": "Q64389-1", "name": "CAMPATH-1 antigen", "aln": "MKSFL-LFLTIILLVVIQIQTGSLGQ------------ATTAASGTN-------KNSTSTKKTP---LKSGASSIIDAGACSFLFFANTLMCLFYLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31358-1", "uniprot_id": "CD52_HUMAN", "id": "P31358-1", "name": "CAMPATH-1 antigen", "aln": "MKRFLFLLLTISLLVMVQIQTGLSGQ-----------------------------NDTSQTSSP-----SASSNIS--GGIFLFFVANAIIHLFCFS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ** *:*** ***::***** ** . *: .:* :.:*.* *. ::*.**::: ** :*", "identical_positions": 28, "similar_positions": 20, "identity": "28.87%" }, { "cls_id": "homologset.agr.RGD:620628", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DAQ9-1", "uniprot_id": "SPT19_MOUSE", "id": "Q9DAQ9-1", "name": "Spermatogenesis-associated protein 19, mitochondrial", "aln": "MIITTWIMYIFARKTVGLPFPPRVNSDIEVEESEAVSVVQHWLNKTEEEASRSIREKMSINDS-------------PTHGHDIHVTRDLVKHHLSKSDMLTDPSQEVLEERTRIQFIRWSHTRIFQVPSEVMDDVMQERIDQVRRSVSHLMCDSYNDPSFRTSCSEC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q920Q3-1", "uniprot_id": "SPT19_RAT", "id": "Q920Q3-1", "name": "Spermatogenesis-associated protein 19, mitochondrial", "aln": "MIITTWIMYILARKSIGLPFPPRVNSDIEVEETEAVSVVQHWLNKTEEEASRSIKEKISINDP-------------CTQGHDIHVTRDLVKHRLSKCDMLTDPNQEVLEERTRIQFIRWSHTRIFQVPSEMMDDVIQERIDQVRRSVSHLRCDSSSDPCYRNSCSEC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z5L4-1", "uniprot_id": "SPT19_HUMAN", "id": "Q7Z5L4-1", "name": "Spermatogenesis-associated protein 19, mitochondrial", "aln": "MIITTWIVYILARKGVGLPFLPITSSDIDVVESEAVSVLHHWLKKTEEEASRGIKEKLSINHPSQGVREKMSTDSPPTHGQDIHVTRDVVKHHLSKSDLLANQSQEVLEERTRIQFIRWSHTRIFQVPSEMTEDIMRDRIEQVRRSISRLTDVSAQDFSMRPSSSDC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:**:*** :**** * ..***:* *:*****::***:********.*:**:***.. *:*:*******:***:***.*:*:: .**************************: :*::::**:*****:*:* * .* . * *.*:*", "identical_positions": 103, "similar_positions": 37, "identity": "61.68%" }, { "cls_id": "homologset.agr.RGD:620629", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZE0-1", "uniprot_id": "TMLH_MOUSE", "id": "Q91ZE0-1", "name": "Trimethyllysine dioxygenase, mitochondrial", "aln": "MWYHKLLHQQSRLRNLMKRGNIAQGLHLSNFKSLFSSSIHWCHTTSKSVNCTWHQHEDHLELQYAGTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIKPKTVHLDETMLFFTWPDGHVTRYDLDWLVKN---SYE---GQKQKVIQPRILWNSKLYQQ--AQVPSVDFQCFLETNEG--LKKFLQNFLLYGIAFVENVPPTEEH---TEKLAERISLIRETIYGR--MWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHE-----GTGGRTLLVDGFYAAQQVLQKAPEEFELLSKVPLKHEYIENVGQCHNHMIGVGPILNIYPWNKELYLIR--------------------YNNYDR--AVINTVPYDVVHR------------WYTAHRTLTTELRRPENELWVKLKPGKVLFIDNWRVLHGRESFTG-YRQLCGCYLTRDDVLNTARLLGLHA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91ZW6-1", "uniprot_id": "TMLH_RAT", "id": "Q91ZW6-1", "name": "Trimethyllysine dioxygenase, mitochondrial", "aln": "MWYHKLLHQQSRLQNLMKRGDIAHGLRLSGFKSLFPFSLHWCHTASKSVNCTWHQHEDHLELQYASTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIKPKTIRLDESTLFFTWPDGHVTRYDLDWLVKN---SYE---GQKQEVIQPRVLWNAKLYQD--AQLPSVDFQGFLETKEG--LKKFLQNFLLYGIAFVENVPPTQEH---TEKLARRVSLIRETIYGR--MWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHE-----GTGGRTLLVDGFYAAQQVLQRAPEEFDLLSQVPLKHEYIENVGQCHNHMIGVGPILNIYPWNKELYLIR--------------------YNNYDR--AVINTVPYDVVRR------------WYAAHRTLTTELRRPENELWVKLKPGKVLFIDNWRVLHGRESFTG-YRQLCGCYLTRDDVLNTARILGLHA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NVH6-1", "uniprot_id": "TMLH_HUMAN", "id": "Q9NVH6-1", "name": "Trimethyllysine dioxygenase, mitochondrial", "aln": "MWYHRLSHLHSRLQDLLKGGVIYPALPQPNFKSLLPLAVHWHHTASKSLTCAWQQHEDHFELKYANTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIKPKTIRLDETTLFFTWPDGHVTKYDLNWLVKN---SYE---GQKQKVIQPRILWNAEIYQQ--AQVPSVDCQSFLETNEG--LKKFLQNFLLYGIAFVENVPPTQEH---TEKLAERISLIRETIYGR--MWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHE-----GTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIEDVGECHNHMIGIGPVLNIYPWNKELYLIR--------------------YNNYDR--AVINTVPYDVVHR------------WYTAHRTLTIELRRPENEFWVKLKPGRVLFIDNWRVLHGRECFTG-YRQLCGCYLTRDDVLNTARLLGLQA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDM7-1", "uniprot_id": "Q9VDM7_DROME", "id": "Q9VDM7-1", "name": "Trimethyllysine dioxygenase, mitochondrial", "aln": "--------------------------------------------------------MLLLKHPKTSQSIEINEFWLRDHCRCVECLNFETNQRRYDVLDLPADIMPLDVKYDGMNLQVQWSDAHKSNYDLDFIFDS---QLERLIGRRSKSTNLTPWNRSIILQN--ERHLRFPLPQLVSSDNE--VRSLVESLVRYGIVFIDDVAPTANM---TELALRRVFPLMKTFFGE--MWTFSDNPDHADTAYTKLYLGSHTDNTYFCDAAGLQALHCIEHS-----GSGGENFFVDGLHVVHELKRRYPAAYDVLCSVQVPGEYIEKG----EHHYHTAPIIQVDPLTQEFVQLR--------------------LNVYDR--AVFNTIPQAEMAE------------FYDSLRQLLLIVRDKQQQWALKLCPGSIVLFDNWRVLHGREAYTG-SRTMSGSYVQRTDFLSKARVLGIID----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23180-1", "uniprot_id": "AIM17_YEAST", "id": "P23180-1", "name": "Probable oxidoreductase AIM17", "aln": "-------MLRSNLCRGSRILARLTTTPRTYTSAATAAAANRGHIIKTYFNRDSTTITFSMEESSKPVSVCFNNVFLRDASHSAKLVTTGELYHNEKLTAP----QDIQISEDGKSLVVKWKDGGHHQFPLQFFIDYKGSSFVSPATRKQESRYRPQLWNKRILKDNVKDLLSVSYNEFIDPKDDSKLFQTLVNLQKFGIAFISGTPSSSSEGLTIQKICERIGPIRSTVHGEGTFDVNASQATSVNAHYANKDLPLHTDLPFLENVPGFQILQSLPATEGEDPNTRPMNYFVDAFYATRNVRESDFEAYEALQIVPVNYIYENGD----KRYYQSKPLIEHHDINEDNTLLGNYEALIKCINYSPPYQAPFTFGIYDKPSDLNNNLDLNLITTPAKLTERFLFKSFIRGLNLFESHINDFNNQFRLQLPENCCVIFNNRRILHANSLTSSNQQWLKGCYFDSDTFKSKLKFLEEKFPHDK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :: .:*** .:... . : . : * * . * *. .: *:::.. . ::.: . : :: . ::...: : . : .: :**.*:.....: . : .*: : .*..*. : :.: :: *:: * *** .:: : *:* ::.: .: . :**.::...:: . :: * * : * : :: *::: .:: : . **: : *.: : : . . : :. ::: ::* . ::::* *:**... :. : : *.*. . .. :.* ", "identical_positions": 38, "similar_positions": 144, "identity": "7.92%" }, { "cls_id": "homologset.agr.RGD:62063", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62806-1", "uniprot_id": "ZN148_RAT", "id": "Q62806-1", "name": "Zinc finger protein 148", "aln": "MNIDDKLEGLFLKCGGIDEMQSSRAMVVMGGVSGQSAVSGELQESVLQDRSLPHQEILAADEVLQESE-----------MRQQDMISHDELMVHEETVKND-EEQTDTHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQVREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKPEKKS------SGMDKESVLDKSDTKKD---RNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASG---EIHPPKLVLKKINSKRSLKQP-LEQSQTISPLSTYEDSKVSKYAFELVDKQALLDSEGSADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNN-SREYALNVGTIASQPSVTQAAVASVIDENTTASIL-DSQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSDVPEVTQSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNPPAFSSIDKQVYAAMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHPFPFSGDETNHASATSTADFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61624-1", "uniprot_id": "ZN148_MOUSE", "id": "Q61624-1", "name": "Zinc finger protein 148", "aln": "MNIDDKLEGLFLKCGGIDEMQSSRAMVVMGGVSGQSAVSGELQESVLQDRSLPHQEILAADEVLQESE-----------MRQQDMISHDELMVHEETVKND-EEQMDTHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQVREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKS------SGMDKESVLDKSDLKKD---KNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASG---EIHPPKLVLKKINSKRSLKQP-LEQSQTISPLSSYEDSKVSKYAFELVDKQALLDSEGSADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNN-SREYALNVGTIASQPSVTQAAVASVIDESTTASIL-DSQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKPNGQHEISFSVADTEVTSSISINSSDVPEVTQSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNPPAFSSIDKQVYAAMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHPFPFSGDETNHASATSTADFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQR1-1", "uniprot_id": "ZN148_HUMAN", "id": "Q9UQR1-1", "name": "Zinc finger protein 148", "aln": "MNIDDKLEGLFLKCGGIDEMQSSRTMVVMGGVSGQSTVSGELQDSVLQDRSMPHQEILAADEVLQESE-----------MRQQDMISHDELMVHEETVKND-EEQMETHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQIREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKS------SGMDKESALDKSDLKKD---KNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASG---EIHPPKLVLKKINSKRSLKQP-LEQNQTISPLSTYEESKVSKYAFELVDKQALLDSEGNADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNN-SREYALNVGTIASQPSVTQAAVASVIDESTTASIL-ESQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVPEVTPSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNQPAFSSIDKQVYATMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHSFPFSGDETNHASATSTQDFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0MS83-1", "uniprot_id": "ZN148_DANRE", "id": "A0MS83-1", "name": "Zinc finger protein 148", "aln": "MNIDDKLEGMLLKYSPVGLQHPSRGLGPSR-VDGRGRRG--SLDMTLGERSLANHPLLAEDDDDEDEEEDDDDDLAGEGLTSHDLISQDDLMVHEETVKNDGQDEAAFSHRISNKLHYTLSMPVNIKQEMKVPDSLILNKKEKKPGRDPSDCHKKKKRKQRSPAKILTINEDGSLGHQNPKSHICEHCNAAFRTNYHLQRHVFIHTGEKPFQCNQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMKFIQKYHMERHKRTHSGEKPYQCDYCHQFFSRTDRVLKHRRMCHENKDRKVQKTAVKDSPLRTPENLGFSFPAKDCTLPKKKRQKTSDKSRASITNPAVDKVVEADMDEKTEDRLAKSECLPLYAVATKVKDEYVVTDYSVELPDSPPGSRHLAGEESNDEIISPPKLVLKKIASRRGFKQQALEQSQSLSPLSSFEESKVTRYTFEIVDNKGLLDVETNPDMESVEALQVGQAKPTGSSTNYDDAMQFVKKRRYLQAATANTSRDYALNVSSIVSQSSVTQASVATVIDETVPATILSETQTLNVEIKSSNEKNVLPDEVLQTLLDHYSNKANGQAEISFSVADTEVTSSISINSSD--ESSPAEALVTSSQAPPTEKASLLQEYSKFLQQALERTSQNDTYLNNQSLTFVNDSASLAGQPLFS--TEKQFTSPPR--FRPTMNSPLRSTLEKPNFNLLV-DTQHSFSFSGDETNPSSVSPTEDFLDQVTSPKKTDPQSISQTFQITTFDQNFRSQFPSSRSGISPQFSIASGQVTLRGHG-GADFPEFSLVN--ETRTQLTSSPDATSSQTFG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********::** . :. :.** : *.*:. . : .* :**:.:: :** *: ::.* : .:*:**:*:*********** ::: .*:.: *:*:*.:*:.:***:...* ::** *:* * :*********************** :.****:*****************************.********************************:**********************:** *:**********:******:*:*::: *:*.. * : *: *** ..** :********...** ..:** * .: .:* :.: ****: :*******:*::*:**:*.*. *. ** . .. * ********* *:*.:** ***.*::****::*:***::*:**:**::.*** * ..*::.*: ** * :**. ***********:**:******: * **:*****.:*.**.*****:**:****...*:** ::*:*******.::***:*************:*.*** ********************: * : :* : :****..::**.:************:******:***. **.**.*. :*.. * ** :: ::: * **. ******:* :*.:*.*:* *:**.*.******* :*.:.* ******** **::.*.: *::*:::*:* **: : .**:**:.*** *.***.*** * .*:*.**.*** :.*: :*******:.****", "identical_positions": 475, "similar_positions": 214, "identity": "57.86%" }, { "cls_id": "homologset.agr.RGD:620630", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYN8-1", "uniprot_id": "HRH3_RAT", "id": "Q9QYN8-1", "name": "Histamine H3 receptor", "aln": "MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGRE-AGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58406-1", "uniprot_id": "HRH3_MOUSE", "id": "P58406-1", "name": "Histamine H3 receptor", "aln": "MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGRE-AGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5N1-1", "uniprot_id": "HRH3_HUMAN", "id": "Q9Y5N1-1", "name": "Histamine H3 receptor", "aln": "MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPP-PPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******** :****:*******************************************************************************************************:**.********************************** ******************************************************************************.** *******:******* **.***** *****************. *.*:*** ****.***:.*******************************************:*********:*******:************************:*:***************************:****************:***.***:***", "identical_positions": 417, "similar_positions": 22, "identity": "93.5%" }, { "cls_id": "homologset.agr.RGD:620631", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91ZY1-1", "uniprot_id": "HRH4_RAT", "id": "Q91ZY1-1", "name": "Histamine H4 receptor", "aln": "----------------MSESNGTDVLPLTAQVPLAFLMSLLAFAITIGNAVVILAFVADRNLRHRSNYFFLNLAISDFFVGVISIPLY-IPHTLFNWNFGSGICMFWLITDYLLCTASVYSIVLISYDRYQSVSNAVRYRAQHTGILKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTEECEP--GFVTEWYILAITAFLEFLLPVSLVVYFSVQIYWSLWKRGSLSRCPSHAGFIATSSRGTGHSRRTGLACRTSLPGLKEPAASLHSESPRGKSSLLVSLRTHMSGSIIAFKVGSFCRSESPVLHQREHVELLRGRKLARSLAVLLSAFAICWAPYCLFTIVLSTYRRGERPKSIWYSIAFWLQWFNSLINPFLYPLCHRRFQKAFWKILCVTKQPAPSQT-QSVSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZY2-1", "uniprot_id": "HRH4_MOUSE", "id": "Q91ZY2-1", "name": "Histamine H4 receptor", "aln": "----------------MSESNSTGILPPAAQVPLAFLMSSFAFAIMVGNAVVILAFVVDRNLRHRSNYFFLNLAISDFLVGLISIPLY-IPHVLFNWNFGSGICMFWLITDYLLCTASVYNIVLISYDRYQSVSNAVSYRAQHTGIMKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTKDCEP--GFVTEWYILTITMLLEFLLPVISVAYFNVQIYWSLWKRRALSRCPSHAGFSTTSSSASGHLHRAGVACRTSNPGLKESAASRHSESPRRKSSILVSLRTHMNSSITAFKVGSFWRSESAALRQREYAELLRGRKLARSLAILLSAFAICWAPYCLFTIVLSTYPRTERPKSVWYSIAFWLQWFNSFVNPFLYPLCHRRFQKAFWKILCVTKQPALSQN-QSVSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3N8-1", "uniprot_id": "HRH4_HUMAN", "id": "Q9H3N8-1", "name": "Histamine H4 receptor", "aln": "----------------MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVGVISIPLY-IPHTLFEWDFGKEICVFWLTTDYLLCTASVYNIVLISYDRYLSVSNAVSYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDEG--SECEP--GFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSVSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PV58-1", "uniprot_id": "A0A8M1PV58_DANRE", "id": "A0A8M1PV58-1", "name": "", "aln": "MAYETEDQETQYCFPNINSSCVKEKRSIREYIIMYLFSSLLSVWIVFLNLLVIISISHFKKLHTPTNMIILSLAVADLLIGLIVMPLQAIKQIETCWYFGESFCGINLILIGLIFSASFSNLVLIAVDRYVAVCHPLLYPRKIT-TAKMLMSILLSWLYYSGYNTGLVINNGYADTSYRTDMCYGECTIIMSFGWILTDMFMFFIFPCLIMITFYVRIFYVVHQQVKVMNSLMKGGKCVTEGSVKRKS----------------------------------------------------------------------ESKAALTLGIIVTVYLLCYIPYYICTLSVNSVTAIN--------VLGWIVYANSGVNPLVYALFYPWFKKTAKIILTLKIFEPASSLINIFK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z8X7-1", "uniprot_id": "A0A8M6Z8X7_DANRE", "id": "A0A8M6Z8X7-1", "name": "", "aln": "MAYETEDQETQYCFPDINSSCVKGKRSRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLFVIPIQAIKLTETCWYFGDIFCVLYLILIGLIFSASLSNLVLIAVDRYVAVCHPLLYPQKIT-ITNMLKSICLSWVCYSAYNTAFVVNNGYFDSSHRTDMCNGRCSVMVSFSWTVIDLFMCFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKRVTESSAKRKS----------------------------------------------------------------------ESKAALTLGIIVTIYLLCYIPYYICSLFVISSTTIT--------VLSWAVHANSGLNPLVYALFYSSFKKTVKHIFTLKIFQPVSFLFRIFK-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . . : : .: * .: . * :**::: ::*: :. ::*.**: *:::*:: :*: * * **. :* : * *: :**. .:***: *** :*.:.: * : * ::: : *: * ::: . . . . * .. .: :: *::* : : :.*:: : :: : .. : * .... : : * :*.::: : :*: ** : :: : : * ** :**::*.* : *:*: *: :. * . .. ", "identical_positions": 52, "similar_positions": 112, "identity": "12.65%" }, { "cls_id": "homologset.agr.RGD:620632", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVB9-1", "uniprot_id": "DVL1_RAT", "id": "Q9WVB9-1", "name": "Segment polarity protein dishevelled homolog DVL-1", "aln": "-------MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERAR---RRNRDEAARTNGHPRGDRR-RELGLPPDSASTVLSSELESSSFIDSDEEDNTSRLSSSTEQSTSSRLIRKHKCRRRKQRLRQTDRASSFSSITDSTMSLNIITVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTIPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAITRTSSSSLTSSVPGA-PQLEEAPLTV-KSDMSAIVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSMLKHGFLRHTVNKITFSEQCYYVFGDLCSNLASLNLNSGSSGA-SDQDTLAPLPHPSV-PWPLG-QGYPYQYPGPPPCFPPAYQDPGFSYGSGSAGSQQSEGSKSSGSTRSS---HRTPGRE-ERRATG--------AGG-----SGSESDHTVPSGSGSTGWWERPVSQLSRGS------------------SPRSQASAVAP-GLPPLHPLTKAY---AVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51141-1", "uniprot_id": "DVL1_MOUSE", "id": "P51141-1", "name": "Segment polarity protein dishevelled homolog DVL-1", "aln": "-------MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERAR---RRNRDEAARTNGHPRGDRR-RDLGLPPDSASTVLSSELESSSFIDSDEEDNTSRLSSSTEQSTSSRLVRKHKCRRRKQRLRQTDRASSFSSITDSTMSLNIITVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTIPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAITRTSSSSLTSSVPGA-PQLEEAPLTV-KSDMSAIVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSMLKHGFLRHTVNKITFSEQCYYVFGDLCSNLASLNLNSGSSGA-SDQDTLAPLPHPSV-PWPLG-QGYPYQYPGPPPCFPPAYQDPGFSCGSGSAGSQQSEGSKSSGSTRSS---HRTPGRE-ERRATG--------AGG-----SGSESDHTVPSGSGSTGWWERPVSQLSRGS------------------SPRSQASAVAP-GLPPLHPLTKAY---AVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14640-1", "uniprot_id": "DVL1_HUMAN", "id": "O14640-1", "name": "Segment polarity protein dishevelled homolog DVL-1", "aln": "-------MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERAR---RRNREEAARTNGHPRGDRR-RDVGLPPDSASTALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAVTRTSSSSLTSSVPGA-PQLEEAPLTV-KSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGT-SDQDTLAPLPHPAA-PWPLG-QGYPYQYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSS---RRAPGREKERRAAG--------AGG-----SGSESDHTAPSGVGSS-WRERPAGQLSRGS------------------SPRSQASATAP-GLPPPHPTTKAY---TVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54792-1", "uniprot_id": "DVLP1_HUMAN", "id": "P54792-1", "name": "Putative segment polarity protein dishevelled homolog DVL1P1", "aln": "-------MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLVEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRSPSFQPDVASSRDGMDNETGTESMVSHRRDRAR---RRNREEAARTNGHPRGDRR-RDVGLPPDSASTALSSELESSSFVDSDEDDSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSMTDSTMSLNIITVTLNMERHHFLGICIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRPDPVRPIDPAAWLSHTAALTGALPR--------------------------PQLEEAPLTV-ESDMNTVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGT-SDQDTLAPLPHPAA-PWPLG-QGYPYQYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRNT---LRPPACEKERRAAG--------SGD-----SDSESDHTAPSGVGSS-WRERPADQLSRGS------------------SPRSQASSYAP-GLPPPHPTTKAY---TVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGK1-1", "uniprot_id": "A0A8M2BGK1_DANRE", "id": "A0A8M2BGK1-1", "name": "", "aln": "-------MAETKIIYHIDEEETPYLVKLSVAPEKVTLADFKNVLSNRPVNSYKFFFKSMDQDFGVVKEEVSDDNAKLPCFNGRVVSWLVLAESSHTDGMSVCTDSHTEHPPPLERTGGIGDSRPPSFHANAVNSRDGLDTETGSEPVLRHRRERERERTRRRRDDFPRLNGHSKAERVVRDSAMGCDSGS-IMSSELESSSFIDSEDEEDASRLSSSTEQSSSFQLMKRHKRRRRRHKVAKIDRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRILREIVSKNGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWISHTTALTGSYPQNGTVFLVTDDCMFSAVKHDLILPLFFTEFDELPLTMGKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGGDVVDWLYSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMATLNLNEGSSGAGSEQDTLAPLPPPSTNPWPMGGQPFPYPPFTAPPAFPPGYSDPCHSFHSGSAGSHHSEGSRSSSSNPSIGRIQRAVPREKERKSTGSESDSGKRAGGRRVERSASQLSHRSHALSSRSHTHSRVPSQHSRTSFSYSHAPFTKYGHTSCALSERSHASSYGPPGLPPPYSLARLTPKGAVCSGPPGAPPVREMGAIPPELTASRQSFQHAMGNPCEFFVDIM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P51140-1", "uniprot_id": "DSH_DROME", "id": "P51140-1", "name": "Segment polarity protein dishevelled", "aln": "MDADRGGGQETKVIYHIDDETTPYLVKIPIPSAQVTLRDFKLVLN-KQNNNYKYFFKSMDADFGVVKEEIADDSTILPCFNGRVVSWLVSADGTNQ------SDNCSELPTSECELGMGLTNRKLQQQQQQHQQQQQQQQQQHQQQQQQQQQQVQPVQLAQQQQQQVLHHQKMMGNPLLQPPPLTYQSAS-VLSSDLDSTSLFGTESELTLDR--DMTDYSSVQRLQVRKKPQRRKKRAPSMSRTSSYSSITDSTMSLNIITVSINMEAVNFLGISIVGQSNRGGDGGIYVGSIMKGGAVALDGRIEPGDMILQVNDVNFENMTNDEAVRVLREVVQKPGPIKLVVAKCWDPNPKGYFTIPRTEPVRPIDPGAWVAHTQALT---------------------SHDSIIADIAEPIKER---LDQNNLEEIVKAMTKPDSGLEIRDRMWLKITIPNAFIGADAVNWVLENVEDVQDRREARRIVSAMLRSNYIKHTVNKLTFSEQCYYVVNEER-NPNLLGRGHLHPHQLPHGHGGHALSHADTESITSDIGPLPNPPIYMP--YSATYN-PSHGYQPIQYG--IAERHISSGSSSSD-----------VLTSKD---------------ISASQSDITSVIHQANQLTIAAHGSNKSSGS------------------SNRGGG--------------G---------GGGGGGNNTNDQDVS---------VFNYVL-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:***:*:* ******:.:.. :*** *** **. : : **:****** ********: **.: ************* .:.:: :*. :: *.. . * .* . : : ..:: : : : :::: :.::: : : .: : : :*.* :**:*:*:*:..::.: .* . *: *: :* ::* :**::: . .*:**:**:*********:**::*** :****.****** ******:********** *********:***********:**:***:***:*.: ***.*.*******.*:.***:**.:*******.**::** *** :.* : :.:: :*:.* *****************.**.**.*.*:*: .**..::**:**: .*::*: .:::*****:********...: * *. . . .. . .*. . . . . . * * :.. *. * .. . . * :* **.*. . : . * *: . . .: * * * *. . .* *. ..: . *: .: ", "identical_positions": 245, "similar_positions": 186, "identity": "32.67%" }, { "cls_id": "homologset.agr.RGD:620633", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63416-1", "uniprot_id": "ITIH3_RAT", "id": "Q63416-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H3", "aln": "MVTLWWPCLVLALLSGLETSGFPRSPLRLLGKRSLPEGVVDGIEIYSTKISCKVTSRFAHNVVTTRAVNRADKAKEVSFDVELPKTAFITNFTLTIDGVTYPGSVKEKEVAQKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVIFELTYEELLKRNKGKYEMYLKVQPKQLVRHFEIDAHIFEPQGISMLDADASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTIVYDVNR-ESPGNVQIVNGYFVHFFAPQGLPVVPKNIAFVIDVSGSMSGRKIQQTREALLKILDDMKEEDYLNFILFSTGVTTWKDHLVKATPANLEEARAFVKNIRDRSMTNINDGLLRGIEMLNKAREDHLVPERSTSILVMLTDGDANTGESRPEKIQENVRNAIRGKFPLYNLGFGNNLNYNFLESLALENHGFARRIYEDSDASLQLQGFYEEVANPLLTNVELEYPENAILDLTRNSYPHFYDGSEIVVAGRLVDR-NVDNFKADVKGHGALNDLTFTEEVDMKEMDAALKEQGYIFGDYIERLWAYLTIEQLLEKRKNARGDEKENITAEALELSLKYHFVTPLTSMVVTKPED-NEDQTAIADKPGE---EAISAST--AYLTSQQSSHSPYYYVDGDPHFIIQVPGKNDTICFNIDEKPGTVLSLIQDPVTGIAVTGQIIGEKGNNASSRTGKTYFGKLGIANAWMDFRIEVTTEKIILGNGDALSTFSWLDTVTVTQTGLSVTINRKKNMVVSFEDGISFVIVLHQVWKKHPVHQDFLGFYVVDSHRMSAQTHGLLGQFFQPFDFKVFDVRPGSDPMKPDATMVVKSHRLTVTRGSQKDYRKDASVGTKVVCWFVHNNGEGFIDGVHTDYIVPSLF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61704-1", "uniprot_id": "ITIH3_MOUSE", "id": "Q61704-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H3", "aln": "MRTMWWPCLVLALLSGLETSGFPRSPLQLLGKRSLPEGVVDGIEVYSTKISCKVTSRFAHNVVTTRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGVTYPGNVKEKEVAQKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRNKGKYEMYLKVQPKQLVRHFEIDAHIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTIVYDVNR-ESPGNVQIVNGYFVHFFAPQGLPVVPKNIVFVIDVSGSMSGRKIQQTREALLKILDDVKEDDYLNFILFSTDVTTWKDHLVQATPANLKEAKTFVKNIHDQSMTNINDGLLKGIEMLNKAREDHTVPERSTSIIIMLTDGDANTGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLETLALENHGLARRIYEDSDANLQLQGFYEEVANPLLTNVEVEYPENAILDLTRNSYPHFYDGSEIVVAGRLVDR-NMDNFKADVKGHGALNDLTFTEEVDMEEMDAALKEQGYIFGDYIERLWAYLTIEQLLEKRKNAKGDEKENITAEALDLSLKYHFVTPLTSMVVTKPED-NEDQTSIADKPGE---EAIAETTTMSFLTTQQSSQSPYYYVDGDPHFIIQIPGKNDSICFNIDEKPGTVLRLIQDPVTGITVTGQIIGDKRSNASSRTGKTYFGKLGITNAWMDFRVEVTTEKIILGTGAELSTFSWLDTITVTQTGLSVTINRKKNMVVSFGDGISFVIILHQVWKKHPVHQDFLGFYVVDSHRMSAQTHGLLGQFFQPFDFKVFGIRPGSDPTKPDATMVVKNHRLTVTRGSQKDYRKDASVGTKVICWFVHNNGEGLIDGVHTDYIVPSLF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06033-1", "uniprot_id": "ITIH3_HUMAN", "id": "Q06033-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H3", "aln": "MAFAWWPCLILALLSSLAASGFPRSPFRLLGKRSLPEGVANGIEVYSTKINSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGVTYPGNVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEIEVDIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTITYDVNR-ESPGNVQIVNGYFVHFFAPQGLPVVPKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKEHLVQATPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGFARRIYEDSDADLQLQGFYEEVANPLLTGVEMEYPENAILDLTQNTYQHFYDGSEIVVAGRLVDE-DMNSFKADVKGHGATNDLTFTEEVDMKEMEKALQERDYIFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTARALDLSLKYHFVTPLTSMVVTKPED-NEDERAIADKPGEDA-EATPVSPAMSYLTSYQPPQNPYYYVDGDPHFIIQIPEKDDALCFNIDEAPGTVLRLIQDAVTGLTVNGQITGDKRGSPDSKTRKTYFGKLGIANAQMDFQVEVTTEKITLWNRAVPSTFSWLDTVTVTQDGLSMMINRK-NMVVSFGDGVTFVVVLHQVWKKHPVHRDFLGFYVVDSHRMSAQTHGLLGQFFQPFDFKVSDIRPGSDPTKPDATLVVKNHQLIVTRGSQKDYRKDASIGTKVVCWFVHNNGEGLIDGVHTDYIVPNLF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N625-1", "uniprot_id": "A0A8M1N625_DANRE", "id": "A0A8M1N625-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H3", "aln": "-------------------------MTKHLKKRSVSS---AEIEVQSVKVDCKVTSRFAHTVMTTKALNKANVSQEVFFEVELPKTSFITNFSMEIDGKMYTGVVKEKEKAQQQYQRAVSSGRTAGLVKASGRKMEKFSVSVNVAAKSSVTFILTHEELLQRRFSKYELMIRVKPKQLVQHFEIVADIYEPQGIAFVDAYGTFITNELLP-LVDKTVTDKKAHVSFSPTLDQQRKCTECDGTLIDGDFFITYDVNRPHDIGDIQIVNGYFVHFFAPANLPRVPKMVVFVIDNSYSMVGNKMAQTKEALGTILGELPEDDYFAIIVFSTTFVVWRPYLSKATEENVKEAQEYVKTIEVIGGTELHDATIHGVEMLYAAQRNGTAPKNMVLMMILLTDGQPNQYPRSLPEIQESIRKAIDGNITLFGLAFGNDADYGFLDTLSKQNNGIVRRIYEDSDAPLQLKGFYEEVSSPLLSEVNFHYPDNTVNSLTRSHFKQLFNGSEIMVAGRLDDLNDINNFDIEVSAQGFDNNFEIKGQANAQKWDTIFPDDEYIFGDFTERLWAYLTIQELLEKKDQGTPEEKGNATADALSLSLKYNFVTPLTSMVVTKPEDEFNNDTLIADKLTEEERGKLQRYGFAGYSAMPVSSHAPTYYVDGDPHFIIELPDKNDALCFNIDDEPGTIFNLVRDPLTGIVVNGQTIGDKKVVPGKKVN-TYFGRFGIIHEKFDVRMTVSTKEISVIEKGKHVKLFWAEAATVKGPNMDLQVNKDRSLTVTLRNSVKFLIILHKVWERHPYHQDYLGFYTLDSHLFSSNVHGLLGQFYHGLEFKVGEPFPGKDPNKVDAIMSVKGQELVVTRGFQRDFRQDVKNGEQVPCWFIHNNGTGLLDGVLTDYIVSGLFKTI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ***:.. **: *.*:..********.*:* :*:*:*: ::** *:******:*****:: *** *.* ***** *::**::***.*:***********:***:******* *.* * **:****:*. .***: ::*:*****:**** ..*:*****:::** .:****:** : *:.:.**.****.*:*****.*. * .:*::*** *.***** .. *::************* .** *** :.**** * ** *.*: **:*** ** :: *:**: :*:** . .*: :* :** *::**: :**.:. . *:::*. ::*:.** *:.: *:. . ::::****:.* :***.:*:** *::.*:.*.***: :*.**:.:: :*:*:.********* ***:******:.***: *:..**:*:: .**:. : ::::****:***** * :::.*. :*..:* *:: :. :.: :: : : : ****:: *********::****:.:. :** * ** **.*****:*************** ::: **** * .: : ..: * ***********::* *:*::*****: ***:: *::*.:**:.*.** *:* ...:. ****::** : :*.:: *:*::* : .: * :: **. .:.: :*:. .:.*:: :.:.*:::**:**::** *:*:****.:*** :*::.*******:: ::*** **.** * ** : **.:.* **** *:*:*:*.. * :* ***:**** *::*** *****..** ", "identical_positions": 416, "similar_positions": 281, "identity": "46.33%" }, { "cls_id": "homologset.agr.RGD:620634", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97609-1", "uniprot_id": "HAIR_RAT", "id": "P97609-1", "name": "Lysine-specific demethylase hairless", "aln": "MESMPSFLKDTPAWEKTAPVNGIVGQEPGTSPQDGLHHGALCLGEPVPFWRGVLSAPDSWLPPGFLQGPKDTLSVVEGEGSRNGERKANWLGSKEGLRWKEAMLAHPLAFCGPACPPRYGPLIPEHSSGHPKSDPVAFRPLHCPFLLETKILERAPFWVPTCLPPYLMSSLPPERSYDWPLAPSPWVYSGSQPKVPSAFSLGSKGFYHKDPNILRPAKEPLAASESGMLGLAPGGHLQQACDAEGPSLHQRDGETGAGRQQNLCPVFLGYPDTVPRTPWPSCPPGLVHTLGNVWAGPGSNSFGYQLGPPVTPRCPSPGPPTPPGGCCSSHLPAREGDPGPCRKCQDSPEGSSSGPGESSEERNKAGS-RASPPSHHTKLKKTWLTRHSEQFECPGGCPGKGESPATGLRALKRAGSPEVQGA-RGPAPKRPSHTFPGTGRQGARAWQETPETSTGSK-AEAQQQEEQRGPRDGRIRLRESRLEDTSCQHHLAGVTQCPSCVQAAGEVEILTSHSQKSHKLPLE-EKPLEE-DSCATSEEGGGSS-PEASINKGLAKHLLSGLGDRLCRLLRKEREALAWAQREGQGPAMTEDSPGIPHCCSRCHHGLFNTHWRCSHCSHRLCVACGRIAGAGK------NREKTGSREQRTDDCAQEAG---HAACSLILTQFVSSQALAELSTVMHQVWAKFDIRGHCFCQVDARVWAPGDGGQQKEPTEKTPPAPQLSCNGDSNRTKDIKEETPDSTESPAEDRAGRSPLPCPSLCELLASTAVKLCLGHERIHMAFAPVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGSGLRKGLSLPLSPVRTQLSPPGALLWLQEPR--PKHGFRLFQEHWRQGQPVLVSGIQKTLRLSLWGMEALGTLGG--QVQTLTALGPPQPTSLDSTAFWKGFSHPEARPKLDEGSVLLLHR-------PLGDKDESRVENLASSLPLPEYCAHQGKLNLASYLPLGLTLHPLEPQLWAAYGVNSHRGHLGTKNLCVEVSDLISILVHAEAQ-----LPPWYRAQKDFLSG----LDGEGLWSPGSQTSTVWHVFRAQDAQRIRRFLQMVCPAGAGTLEPGAP----GSCYLDSGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTISVTQHFLSPETSALSAQLCHQGASLPPDHR--MLYAQMDRAVFQAVKVAVGTLQEAK--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61645-1", "uniprot_id": "HAIR_MOUSE", "id": "Q61645-1", "name": "Lysine-specific demethylase hairless", "aln": "MESMPSFLKDTPAWEKTAPVNGIVGQEPGTSPQDGLRHGALCLGEPAPFWRGVLSTPDSWLPPGFLQGPKDTLSLVEGEGPRNGERKGSWLGGKEGLRWKEAMLAHPLAFCGPACPPRYGPLIPEHSGGHPKSDPVAFRPLHCPFLLETKILERAPFWVPTCLPPYLMSSLPPERPYDWPLAPNPWVYSGSQPKVPSAFGLGSKGFYHKDPNILRPAKEPLAES--GMLGLAPGGHLQQACESEGPSLHQRDGETGAGRQQNLCPVFLGYPDTVPRAPWPSCPPGLVHSLGNIWAGPGSNSLGYQLGPPATPRCPSPGPPTPPGGCCSSHLPAREGDLGPCRKCQDSPEGGSSGPGESSEERNKADS-RACPPSHHTKLKKTWLTRHSEQFECPGGCSGKEESPATGLRALKRAGSPEVQGASRGPAPKRPSHPFPGTGRQGARAWQETPETIIGSK-AEAEQQEEQRGPRDGRIRLQESRLVDTSCQHHLAGVTQCQSCVQAAGEVGVLTGHSQKSRRSPLE-EKQLEEEDSSATSEEGGGGPGPEASLNKGLAKHLLSGLGDRLCRLLRKEREALAWAQREGQGPAMTEDSPGIPHCCSRCHHGLFNTHWRCSHCSHRLCVACGRIAGAGK------NREKTGSQEQHTDDCAQEAG---HAACSLILTQFVSSQALAELSTVMHQVWAKFDIRGHCFCQVDARVWAPGDGGQQKEPTEKTPPTPQPSCNGDSNRTKDIKEETPDSTESPAEDGAGRSPLPCPSLCELLASTAVKLCLGHDRIHMAFAPVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGSGLRKGLSLPLSPVRTRLSPPGALLWLQEPR--PKHGFHLFQEHWRQGQPVLVSGIQKTLRLSLWGMEALGTLGG--QVQTLTALGPPQPTNLDSTAFWEGFSHPETRPKLDEGSVLLLHR-------TLGDKDASRVQNLASSLPLPEYCAHQGKLNLASYLPLGLTLHPLEPQLWAAYGVNSHRGHLGTKNLCVEVSDLISILVHAEAQ-----LPPWYRAQKDFLSG----LDGEGLWSPGSQTSTVWHVFRAQDAQRIRRFLQMVCPAGAGTLEPGAP----GSCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTISVTQHFLSPETSALSAQLYHQGASLPPDHR--MLYAQMDRAVFQAVKAAVGALQEAK--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43593-1", "uniprot_id": "HAIR_HUMAN", "id": "O43593-1", "name": "Lysine-specific demethylase hairless", "aln": "MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSWLPPGFPQGPKDMLPLVEGEGPQNGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCGPLMPEHSGGHLKSDPVAFRPWHCPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWPLTPHPWVYSGGQPKVPSAFSLGSKGFYYKDPSIPRLAKEPLAAAEPGLFGLNSGGHLQRAGEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSEEVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDPGLQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEEGPGSGPDSRLSTGLAKHLLSGLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCCSRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGR------AREKAGFQEQSAEECTQEAG---HAACSLMLTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWAPGDAGQQKESTQKTPPTPQPSCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLCLGHERIHMAFAPVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLPPPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGG--QVQALSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGSVLLLHR-------ALGDEDTSRVENLAASLPLPEYCALHGKLNLASYLPPGLALRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHADTP-----LPAWHRAQKDFLSG----LDGEGLWSPGSQVSTVWHVFRAQDAQRIRRFLQMVCPAGAGALEPGAP----GSCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHFLSPETSALSAQLCHQGPSLPPDCH--LLYAQMDWAVFQAVKVAVGTLQEAK--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHC5-1", "uniprot_id": "KDM3_DROME", "id": "Q9VHC5-1", "name": "Lysine-specific demethylase 3", "aln": "------------------------------------------------------------------------------------------------------MSQKELAALVATRTSRKRTISSTSFSISTRTDPKS--------IIEIHIFN---------------DSLPIKR---------------------------------------------------------------ACCEVENPTLKAEQRVQQEEESLGQVPPLTE-EEQQRHDEFRNSGSIFLQDLP---------CFKLQQAQPIAGSSPIP----------------------KCRECRRRNLATTEGE-----------------PSSVSDVYCRFYEFRRLQFNENG--------------ELCVVGFP---------------NPYSEPSPEDIAIWQPDKNTPPTSG-------------------------------------------------------------------------------------------YMDIQVCRYILLHAGDQFCYIWHQEAEALSLHQNTDGTIAWKKAVKGTREICDVCDTTLFNYHWTCRKCGFGVCLDCVKDRKEGLRLRRAENAAQKGCDEYHWLLCSDPSGPQEHVLTELMLTQIIAGDALNVLGRLLHEVRTLWQVPQVCGCLLSKQAIEDAQSKEVIQDMIKESQLKQHTSYSSLASEQKVHQQQRLDQLHATKLEFAR----ELGVDYVPGRVWTKETLGKDPITTAFDNLKHINFLRKGLAGLRR-----FLPPRTMTFAYSTQLAPG-------------VPHEFLCDGRLLRLTDAMH--PDNRVLFQEVWKCGQPVMISEVARSLNLDLWHPQAFCRDFGDKPNDLINCLNGNLVPNQPMRHFWEGFQCMTKRLPDAYGKPMLLKLKDWPPGDDFAEILPTRFADLMKGLPMPEYTLRTGNLNIASCLPKMFVPPDLGPKMYNAYGSALHP-DKGTTNLHLDISDAVNIMVYVGIPQDGDTRPQMAATQKAIEIGGCDYITRARCQSPDVLPGALWHIFPARDADKIRDLLNRVTLEKGFRLEPDHDPIHDQNWYLDDKLRARLFKEYGVEGHPIVQCLGDAVFIPAGAPHQVQNLHNCIKVAEDFVSPENITHCYHLTHEFRRLSHSHTNHEDKLQIKNIIYHAIKDCCTILTRAVDERLNAELTKLNAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ** .: ..* .: . . ::** : ::* :*:: ..** :: . : * *:*: .: .. . * : : : . . ::: * : * . * : .* * * :*: . :.* ** :.: : : **: * .* * ..:. .. :. ** :* . :. :.:::* **::* : ::* ***: *. . * .: * . *. *. *** ** * :*.. :*: * : * : * * *:: :* *. .*:***:::.:** *. :*:* . ::: * * . :. .:. : : * . * :. .. :.:::: . .:: .* .: : . . .* **:: * ** :. . ::.: .: : * .. * .* * .: * ** * :. . **** *: ****::* : ::*. .** :*: * : :. *. .. **:**. * *. :**: :.: :*. :* .**:*** *:**:** ** :. * *::: *** * . **.** ::::* :.*:*:. * :** : * : **. .::**:* *:**::** :*: * . ***. . *** ** ** :*:**. .::*. *:**::*********.* . :.*::.*:***. : . :* *: *. . *:. :::*:* . * .* ", "identical_positions": 195, "similar_positions": 255, "identity": "15.78%" }, { "cls_id": "homologset.agr.RGD:620635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W4R3-1", "uniprot_id": "Q9W4R3_DROME", "id": "Q9W4R3-1", "name": "", "aln": "---------------------------------------MPVSAKRLLRNFQFTS------------------------CDRNGKMLIHLLLIVS-----------------------------------------------------------LLEAIGAFQPEFVESISNVSVAVGRDATFTCHVRHLGGYRVG-----------WLKADTKAIQAIHENVITHNPR---VTVSHLDQN---TWNLHIKAVSEEDRGGYMCQLNTD-PMKSQIGF-LDVVIPPDFIS--EDTSSDVIVPEGSSVRLTCRARGYPEPIVTWRREDGNEIVLKD-NVGTKTLAPSFRGEVLKLSKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHPVIQVPNQLVGAPLGTDVQIECHVEASPKSINYWIK----------------DTG----EMIVTSGKYHVQESS-QSMYETKMSMIVRKFQKDDVGSYRCIAKNSLGEVDSSIRLYEIP-GPNRNKNPLNGGGKGGGAGGSLDADANDILKQKQQVKVTYQPEDEELQYGSVEDFEAEGGEGGGLTPLSPHVYYTSGNKPATHKPGNSGGNQHLHQQHHHHHHHNNNNNNQQHSGGPGGGPTGGD-----------AGSLGGEMGGITRKPPPYYGGNTEVRGPIDNNEMSSGSGDSRLCRGHHLPILLLPFARLILVRSWHCRHTFL---------------------------------MGLSQACLPGLLLSLL-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z153-1", "uniprot_id": "B7Z153_DROME", "id": "B7Z153-1", "name": "", "aln": "--------MMNLLVVKESGERIADISCSQEHTTKFSPKLSQVAKHRKLAQLEIASGSGLVGLG--------TGTGTGSGCGPAIRWQLLLLLLLGNCIDLT--------------------------------------------------VSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVITNNDR---LSVQHNDYN---TWTLNIRGVKMEDAGKYMCQVNTD-PMKMQTAT-LEVVIPPDIIN--EETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARN-GSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQR----------------ENG----EMIIAGDRYALTEKE-NNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRLYEME-RPG--KKILR------------DDDLNEVSK-NEVVQKDTRSED-------------------GSRNLNGRLYKDR----APDQHPASGSDQLLGRGTMRLIGTFLLALLVLFTALAEAGPTTLS-----------CRTKGGRQ---KKAKETSWNGRRARDGREDGH-----AAEWRQCWER---------------SALSWRRSAP---------------------------------PELDYYSLIQL----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAR6-1", "uniprot_id": "Q9VAR6_DROME", "id": "Q9VAR6-1", "name": "", "aln": "--------------------------------------MEKLLQSTLFVILIMAT-----------------------KCGSGSTQNQHHE----------------------------------------------------------------SSSQLDPDPEFIGFINNVTYPAGREAILACSVRNLGKNKVG-----------WLRASDQTVLALQGRVVTHNAR---ISVMHQDMH---TWKLKISKLRESDRGCYMCQINTS-PMKKQVGC-IDVQVPPDIIN--EESSADLAVQEGEDATLTCKATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDVPPAVSKRVSLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASPSPVSYWLKGARTSNGFASVSTASLESGSPGPEMLLDGPKYGITER--RDGYRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEIKLHPG--ASASN------------DDHLNYIGGLEEAAR-------------------------------------------------NAGRSNRTTWQPLLAMLMLLWMRLSLRTGGA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7PLL7-1", "uniprot_id": "Q7PLL7_DROME", "id": "Q7PLL7-1", "name": "", "aln": "----------------------------------------MLTKKTARIKMYNGT------------------------LACSIAFILIKAITITKCHAVA--------------------------------------------------HIHGKGESEEIDPQFLAKLSNTTVPIGRDISFTCVVDNLGHYRVA-----------WIKSDSKAILGIHTHMVSLNPR---LSVTHNGHN---TWKLHISRVQINDSGSYMCQVNTD-PMKSLSGY-LDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRPKVLWRREAGKEIILRT-DGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPPSVSKRFNVYVNFSPTVKAISQLVGAPVEREVTLECIVEVFPKPLNGWYR----------------SEGN---IKLHNGNKYNISEEV-INIYTWHLNLTIRHLTKSDFGTYSCSSVNALGKSESLIRLQELRLPPKLTTTPTPHMQTTGKS--RRKHPASHKKGLNEVLRFQETHFAN-------------------QIQQENEDHNEGFDLLKFTNSENSNIVLESGHINSMINKEDVNIYHPKQYGQEKTNKPSGT-----------IPSTRTPWILTNAGSQRPALTSYATVALITSFWLFFWRVFHSLDWDAIRVSSVVHHVVVFKRRSYFEAPNYA---------------------------------LRITVLQMLQELRTLVIEQ--------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMN9-1", "uniprot_id": "Q9VMN9_DROME", "id": "Q9VMN9-1", "name": "", "aln": "-------------------------------------------MQSNFCQCRKQ--------------------------TCALSVILLLILMSQQCYPQR---------------------------------------------VEVPAEVIVD-------PKFSSPIVNMTAPVGRDAFLTCVVQDLGPYKVA-----------WLRVDTQTILTIQNHVITKNQR---IGIANSEHK---TWTMRIKDIKESDKGWYMCQINTD-PMKSQMGY-LDVVVPPDILDY--PTSTDMVVREGSNVTLKCAATGSPEPTITWRRESGVPIELAT-----GEEVMSIEGTDLVIPNVRRHHMGAYLCIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINYWTRER---------------GEIVP-----PGGKYSANVTE-IGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKLYRIPPN--------------------AVNYVENFEARHKGKKRTK------------SSES-------HHPARAQEHSGEDMENP-----GKRKADLS--------LGAES--------IDSIYGNSA--------------AGSRRR--------------------------QDLGGVLLLLLPVAVAVAMSLATAGVMRETQMTLPPQT------------------------------------LTHV---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMN6-1", "uniprot_id": "Q9VMN6_DROME", "id": "Q9VMN6-1", "name": "", "aln": "----------------------------------MKIKIFPLTADAATIAARRQRRRAAGKLQRKREMPEISSRLIVATATAAVVSIICLSLALPGCAAQESDDEGELHHLDQMHHQHQDFIIGESEEHDHIAHHLAEMQNKDELLEDIREDTVVNAIPEKDLPKFGELLQNVTVPVSREAVLQCVVDNLQTYKIA-----------WLRVDTQTILTIQNHVITKNHR---MSITHAEKR---AWILRIRDVKESDKGWYMCQINTD-PMKSQVGY-LDVVVPPDILDY--PTSTDMVIREGSNVTLKCAATGSPTPTITWRREGGELIPLPN-----GAEAVAYNGSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVMLIVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINYWMKN----------------DTIIV-----PGERFVPETFE-SG-YKITMRLTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLYHIPQTTTMTTMAPT----------VSINTVPVVLVKYNKEQRYG------------SSQNSNTNPYNFNPGNSQQNTKLQRGKS-----NSKGSDQSPSGLNNVFVGATSSLWNSQDHHSSSSSSSS--------------ASSRGRDH---HQQQHHQQQQQNHGSDHGASYRSDGKSPHLTNHDAKSLTDDLDRMQDLKGWASRLSPISP--------------------------------ILGLSMILGVGYLGPWPG----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IP70-1", "uniprot_id": "Q8IP70_DROME", "id": "Q8IP70-1", "name": "", "aln": "---------------------------------MAMAGPHRLPRPHTRRRFRLQAEFN------------VRQLAITIIATAAVTMLMTATPTLAEIPSKG---------------------------------------------KHTRLDTQQTAQEDSDFPRFAEPIANVTVSVGRDALMACVVENLKGYKVA-----------WVRVDTQTILSIHHNVISQNSR---ISLTYNDHR---SWYLHIKEVEETDRGWYMCQVNTD-PMRSRKGY-LQVVVPPIIVEG--LTSNDMVVREGQNISLVCKARGYPEPYVMWRREDGEEMLIG------GEHVNVVDGELLHITKVSRLHMAAYLCVASNGVPPSISKRVHLRVQFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYWTTER---------------GDMIISDTSRAGDKYETTSTV-SG-YTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTP-------TT----------AIISEMSLLNRSYDGKRRHRNKFDSANALPDYGVEEWRDGAQGNNAGNNGDNNQTPVRNPPGAFHNSAGSLAQHNLLAKIMLGIKTQSFGIFKRLSSSLPLAAGQSFLWLSTLSLVSAPSRWRMSNVENRPNSPETVVNNDTAAECWETRSHCVSESNNNNNSRITQRPPMWARHLRIFHIAHTPCGASTQYQRLCERQWQWQRLWQWQCQWKWQHQWQWPMLICIVILAGCFVRWLPMLLHFIGRHIGTFSISATHRQHLMCTFWDNRGNKVVAKNTTPARPSTFEMLCSRMFSR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLF0-1", "uniprot_id": "Q9VLF0_DROME", "id": "Q9VLF0-1", "name": "", "aln": "MLPPSWHLIGALLVLAATAGDSTNKIILPQILNGGGGGGGVGTAQGKHPSGSKTVATGVVPNFGGAAGNGAGGGGPVAGSGTGSTVVGSNGVIVAGGGANVP---------------------------------------------------TSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVA-----------WMHFEQSAILTVHNHVITRNPR---ISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTV-TAKTQFGY-LNVVVPPNIDDS--LSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNSRIAINK-----NHIVNEWEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGE--------------------GPIIHDSHKYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPPTTASSGIYS------------TDTHWGENGINNNYAYGG-------------------------PDSTRSIYAQDKNTRYQSNLNEIGLSEQKSFLDKTQNPLLANGNANEADAESNGARGHNP--------------------------------------------------SMAIAWLFVVIATLLLTIRSAVGSSHSLSLC--------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32736-1", "uniprot_id": "OPCM_RAT", "id": "P32736-1", "name": "Opioid-binding protein/cell adhesion molecule", "aln": "----------------------------------------MGVCGYLFLP-----------------------------WKCLVVVSLRLLFLVPTGVPVR-----------------------------------------------------------SGDATFPKAMDNVTVRQGESATLRCTIDDR-VTRVA-------------WLNRSTILYAGNDKWSIDPR---VIILVNTPT---QYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVH-LIVQVPPQIMN----ISSDITVNEISSVTLLCLAIGRPEPTVTWRHLSVK-----------EGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKED--------------------------TRLATGLDGVRIENKGRISTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDG--------------------------------------------------------------------------------VNSASRALACLWLSGTFFAHFFIKF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G5E8G3-1", "uniprot_id": "G5E8G3_MOUSE", "id": "G5E8G3-1", "name": "", "aln": "----------------------------------------MGVCGYLFLP-----------------------------WKCLVVVSLRLLFLVPTGVPVR-----------------------------------------------------------SGDATFPKAMDNVTVRQGESATLRCTIDDR-VTRVA-------------WLNRSTILYAGNDKWSIDPR---VIILVNTPT---QYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVH-LIVQVPPQIMN----ISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVK-----------EGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKED--------------------------TRLATGLDGVRIENKGRISTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDG--------------------------------------------------------------------------------VNSASRALACLWLSGTFFAHFFIKF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14982-1", "uniprot_id": "OPCM_HUMAN", "id": "Q14982-1", "name": "Opioid-binding protein/cell adhesion molecule", "aln": "----------------------------------------MGVCGYLFLP-----------------------------WKCLVVVSLRLLFLVPTGVPVR-----------------------------------------------------------SGDATFPKAMDNVTVRQGESATLRCTIDDR-VTRVA-------------WLNRSTILYAGNDKWSIDPR---VIILVNTPT---QYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVH-LIVQVPPQIMN----ISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVK-----------EGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEE--------------------------TRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDG--------------------------------------------------------------------------------VNSASRALACLWLSGTLLAHFFIKF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15364-1", "uniprot_id": "AMAL_DROME", "id": "P15364-1", "name": "Protein amalgam", "aln": "--------------------------------------------------------------------------------MARLRLLIGLIFCLAISLDSVLS-----------------------------------------------------------APVISQISKDVVASVGDSVEFNCTVEEVGQLSVSWAKR-------PSESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPVIAEN---TPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGG---------HLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHKNG----------------------VPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHADARLHLFQTVIPVPSLS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . : * : . :. . .:: : : : : : : * : * * * *.: . : : : ** : . . . * . * * . * * * : * : * : : * . . * * * *. . : . : :.: * : . : * . * . * : . . : * * * : * * :. : * ", "identical_positions": 31, "similar_positions": 60, "identity": "3.77%" }, { "cls_id": "homologset.agr.RGD:620636", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P69744-1", "uniprot_id": "TRPV5_MOUSE", "id": "P69744-1", "name": "Transient receptor potential cation channel subfamily V member 5", "aln": "--------------------------------------------------------MG-----AKTPWIQLQKLLN-WWVRDQDWNQHVDQLHMLQQK---SIWESPLLRAAK----------------ENDMCTLKKLQHDQNCDFRQRGALGETALHVAALYDN---LDAAIMLMEAAPYLVTESTLCEPFVGQTALHIAVMNQNVNLVRALLARGASAS-------ARATGSAFHRSS---------------HNLIYYGEHPLSFAACVGSEEIVRL-LIEHGADIRAQDSLGNTVLHILVLQPNKTFACQMYNLLLSYDG-GDHLKSLELVPNNQGLTPFKLAGVEGNTVMFQHLMQKRKRIQWSFGPLTSSLYDLTEIDSWGEELS------FLELVVSSKKKEARQILEQTPVKELVSLKWKKYGQPYFCLLGALYIFYMVCFTTCCVYRP-----------------------LKFRDANRTHVR-DNTIMEQKSLQEAYVTYQD---------------------------KIRLVGELVTVIGAVIILLLEIPDIFRVGASRYFGQTVLGGPFHVIIITYASLVLLTMAMRLTNVNGEVVPMSMALVLGWCS-VMYFARGFQMLGPFTIMIQKMIFGDLLRFCWLMAMVILGFASAFYIIFQTEDPDNLG-----EFSDYPTAMFSTFELFLTIIDGPANYR-----VDLPFMYSVTYATFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICG-------CEYGLGDRWFLRVEHHQEQNPYRVLRYVEAFKSSDKEEVQEQLSEKQPSGTETGTLARGSVVLQTPPLSRTTSLSSNSHRGWEILRRNTLGHLNLGLDPGEGDGEEIYQF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JIP0-1", "uniprot_id": "TRPV5_RAT", "id": "Q9JIP0-1", "name": "Transient receptor potential cation channel subfamily V member 5", "aln": "--------------------------------------------------------MG-----VKKPWIQLQKRLN-WWVREQDWNQHVDQLHMLQQK---SIWESPLLRAAK----------------ENDMCTLKRLQHDQNCDFRQRGALGETALHVAALYDN---LDAAIMLMETAPYLVTESTLCEPFVGQTALHIAIMNQNVNLVRALLARGASAS-------ARATGSAFHRSS---------------HNLIYYGEHPLSFAACVGSEEIVRL-LIEHGADIRAQDSLGNTVLHILVLQPNKTFACQMYNLLLSHDG-GDHLKSLELVPNNQGLTPFKLAGVEGNTVMFQHLMQKRKHIQWSLGPLTSSIYDLTEIDSWGEDLS------FLELVVSSKKKEARQILEQTPVKELVSLKWKKYGQPYFCLLGMLYIFYMICFTTCCVYRP-----------------------LKFRDANRTHVR-DNTVLEQKPLQEAYVTYQD---------------------------KVRLVGELVTVIGAVVILLIEIPDIFRVGASRYFGHTVLGGPFHVIIITYASLVLLIMVMRLTSMNGEVVPISMALVLGWCS-VMYFSRGFQMLGPFTIMIQKMIFGDLLRFCWLMAMVILGFASAFYIIFQTEDPESLG-----EFSDYPTAMFSTFELFLTIIDGPANYS-----VDLPFMYHLTYFAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICG-------CEYGLGDRWFLRVEHHQEQNPYRVLRYVEAFKSSDKEEVQEQLSEKQPSGTETGTLARGSVVLQTPPLSRTTSLSSNSHRGWEILRRNTLGHLNLGQDLGEGDGEEIYHF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQA5-1", "uniprot_id": "TRPV5_HUMAN", "id": "Q9NQA5-1", "name": "Transient receptor potential cation channel subfamily V member 5", "aln": "--------------------------------------------------------MGGFLPKAEGPGSQLQKLLPSFLVREQDWDQHLDKLHMLQQK---RILESPLLRASK----------------ENDLSVLRQLLLDCTCDVRQRGALGETALHIAALYDN---LEAALVLMEAAPELVFEPTTCEAFAGQTALHIAVVNQNVNLVRALLTRRASVS-------ARATGTAFRHSP---------------RNLIYFGEHPLSFAACVNSEEIVRL-LIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKRRHIQWTYGPLTSILYDLTEIDSWGEELS------FLELVVSSDKREARQILEQTPVKELVSFKWNKYGRPYFCILAALYLLYMICFTTCCVYRP-----------------------LKFRGGNRTHSR-DITILQQKLLQEAYETRED---------------------------IIRLVGELVSIVGAVIILLLEIPDIFRVGASRYFGKTILGGPFHVIIITYASLVLVTMVMRLTNTNGEVVPMSFALVLGWCS-VMYFTRGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPTSLG-----QFYDYPMALFTTFELFLTVIDAPANYD-----VDLPFMFSIVNFAFTIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKLPRCLWPRSGICG-------CEFGLGDRWFLRVENHNDQNPLRVLRYVEVFKNSDKEDDQEHPSEKQPSGAESGTLARASLALPTSSLSRTASQSS-SHRGWEILRQNTLGHLNLGLNLSEGDGEEVYHF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QN56-1", "uniprot_id": "F1QN56_DANRE", "id": "F1QN56-1", "name": "", "aln": "--------------------------------------------------------MP---PAISGEINHWWRQMRFRLQHKKGWNEMLDETFLMQTK---RVNDIPLFSATK----------------ENNAACIKKLLDCSSTDIFERGELGETALHVAVMNDN---FEAAVALMNGAPELINEPMTSELYHGLTALHIAVINQNPNLIWEMIKRGADVTT------PRVTGMYFRKRR---------------EGLFYYGEHILAFAACVGNKDIMSM-LIKAGANIRAQDSRGNTILHLLVLQPNKTTACQIFDFLLAQDAEQDSALPLDMVPNYKGLTPFKLAARDGNVVVFQHLVNRRKVVQWSLGPVSSYLYDLTEIDSRVDEHS------VLEIIATSHKKEARRILELTPVRQLITLKWNLYGKHYFRSLMVIYLVYISIFTVCCINRP-----------------------LKGIPENYTKAGNDHTIKIKKTFKESYQSYTD---------------------------QLRLIAEIISLIGAIIILLIEIPGILAVGVKRFFGQTALGGLFHVTLISYALLVLLLCGLRVTGIQGELIPMAFSLILGWFS-LVYFARGFEMLGPYVIVIQKSIFGDITKFMWLSIIFLIGSSAALWIFYMTQEPLALP-----QYRSFPITLFSQFEVSVGQIDLPVDHT-----LFTHPVVYWTHVCFSLISNVLLFNLLVAMMSDTQWRVTQERDELWRTQVVATTLMLERKLPQCLWPRLGVCG-------LMFGLGERWYLRVEDRNDIMAQKLKRYVDAFS-----KDVEAPKEEKPSKSDG----------EQSIAESNKEKSKKSKQYWSLIRR------SIECEKEECVDCPNFKFL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PI57-1", "uniprot_id": "M9PI57_DROME", "id": "M9PI57-1", "name": "", "aln": "---------------MGNTESNVTSGVKKQAGVSTQALYKFVNLKGGGLLVDMMKRACQTKQFAEIDHAIKTKVEPFLYNKGAGRYFPISKLVLLRNRDRPRTRQLPEIRALENPDDDFNIHDYCPEVSEAEYISNPTAYRFVCWDLNMRGAVGETILHLCLLNASSLHADLAKRLLKFYPKLILDIYMSDEYYGESVLHIAIVNEDPAMVKYLLDANADVQERCCGAFMSAEDTKFSRTDSPDHEYVALCPMTNYDGYVYWGEYPLSFAACLSQEECFRL-VLARGADPDFQDTNGNTVLHMLVIYEK-----------IEMFDVGYEVGTNIHIKNIQNLTPLTLAAKLGRVEMFFHVMSIEREIYWQLGSITCAAYPLLMIDTINEETGNINKDSVLNFVVFGDKLEHLELLDG-VVIDLLKTKWDTFCKSRFYKQFYMFALYFLISLFSFILRPGPDAKDEDEDGANSTTAKSDLYRQNGSDSYHLHSKRATMTTEYKTFWLNFTEYYDPSEVEVLPAWWESYAQCPLMNLESDLAKLRIMAELLNFVGAILYLLVALREARFLGLKMFIEN-LMTAPSRVMFLFSCALMMTIPWLRVSCLTEIDDHVTVVIMLTTAPYFLFFCRGFKTVGPFVVMIYRMVMGDLLRFVSIYLVFVMGFSQAFYIIFLTFDNPSSPEDQDAESNPMPSPMESIVAMFLMSLTNFGDYYGAMVSTQHEYEAKILFFLFMVIVSVLLVNMLIAMMGNTYQKIAEIRN-EWQRQWARIVLVVERSVPPAERLKNFMQY-------SQSMSDGRRALVLRLNMTEEEKEEMKEVQEMKR---------------------------------IHQRFAKKRQMEREARALRRQQEYEKFFGTAPKSECSDNNNF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W3W0-1", "uniprot_id": "Q9W3W0_DROME", "id": "Q9W3W0-1", "name": "", "aln": "MKFLLKKCLRKKAPEMKPGAILDAVISQSSATACKCLLYKLADYKRGGDLIDAINSGG----LIAVEQLIREQFGVFMYNDGKGQVINRAEFLRWKYR-DHTEVTIPIEASLS-----------------IHDPLGKWEDHKACWQMQYRGALGESLLHVLIICDSKVHTKLARVLLRVFPNLALDVMEGEEYLGASALHLSIAYSNNELVADLIEAGADIH-------QRAIGSFFLPRDQQRAN---PAKSTDYEGLAYMGEYPLAWAACCANESVYNL-LVDCGSDPDAQDSFGNMILHMVVVCDKLD--------MFGYALRHPKTPAKNGIVNQTGLTPLTLACKLGRAEVFREMLELSAREFWRYSNITCSGYPLNALDTLLPDGRTN-WNSALFIILNGTKPEHLDMLDGGIIQRLLEEKWKTFAQNQFLKRLLILSTHLLCLSVSVYLRPAHDG------------------EAEDEDSEGSDASAAALLDIQSDEGDSGGGDYN------------------------AQTVARYCAEFATLVGVLSYVIFQQGDEIKNQGLSAFLKQLSHAPAKAIFLFSNLLILACIPFRLIGDTDTEEAILIFAVPGSWFLLMFFAGAIRLTGPFVTMIYSMITGDMFTFGIIYCIVLCGFSQAFYFLYKGHPQVQST-----MFNTYTSTWMALFQTTLGDYNYPDLNQ-----TTYPNLSKTVFVIFMIFVPILLLNMLIAMMGNTYVTVIEQSEKEWMKQWAKIVVTLERAVPQADAKGYLEAYSIPLGPSDDSGFEVRGVMVIKSKSKTRAKQRKGAVSNWKRVG-RVTLTALKKRGMTGEEMRRLMWGRASISSPVKVTKQKLKDPYNLHTDSDFTNAMDMLTFASNPASSNGVTLRSVTAPPPAPPAPDPFRELIMMSDQRPETHDPHYFAGLQQLANKAFDLVEQTMKTQPQAPVAKKVDPLPVASVAKASPAAPATQATATAAAASDLMAMPLPISNLSNLFQDPKDIVDPKKLEEFMAMLAEVETEESDSGGPILGKLSLAKRTHNALSKAEIRRDQQGFEGHSHGQFQPMSSVWAPPGLDVDTGFHFDEAVAEEVLTIEQEAEVETEDGNGGQDSEDIPTAEEVHATMKQFHLRKCQPAQDEAARRAKSARVRRRNKVSPEQSDDPDERSQRGRSAYTRRTQSPPDPLEPWSTRELQDINKILARK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12324-1", "uniprot_id": "YVC1_YEAST", "id": "Q12324-1", "name": "Calcium channel YVC1", "aln": "--------------------------------------------------------------MVSANGDLHLPISNEQCMPENNGSLGFEAPTPRQILRVTLNLKYLIDKVVP----------------------IVYDPNDIVCDHSEILSPKVVKLAYEACGGNPKDKANKRKYQSVIIFSLLKVCEWYSILATMEVHNAKLYETRNLASQQLCKLLIER-------EETRDLQF----------------------LFMQLLLRRYVINENDEDQEPLNALELATDMHCTTVIGSSGFQRCLKWIWRG--------WIVQNGLDPTTFIKDDSLAEVSLISHFNPVRLKAPVYQNYLQMIFSFLFLGLYTLVVNGKDSERVQSFDLLES--------IFYVFNTGFILDELTKLYYIGYAHLSFWNLFNDTTYLIITFAMGFRAMSVTPLNAKYSS---------------------EDWDKISYRVLSCAAPFVWSRLLLYLESQRFIG-----------------------------IMLVILKHMMKESIVFFFLLFLIMIGFTQGFLGLDSADGKRDITGPILGNLTITVLGLGSFDVFEEFAPPYAAILY-----YGYYFIVSVILLNILIALYSTAYQKVIDNADDEYMALMSQKTLRYIRAPDEDVYVSP------LNLIEVFMTPIFRILPPKRAKDLSYT----------VMTIVYSPFLLLISVKETREARRIKYNRMKRLNDDAN-EYDTPWDLTDGYLDDDDGLFSDNRNSGMR--------ATQLKNSRSLKLQRTAEQEDVHFKVPKKWYKN----------------------VKKCSPSFEQYDNDDTEDDAGEDKDEVKELTKKVENLTAVITDLLEKLDIKDKKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * . . . :* : . : : . . * : :. .:. : : .:: *. :: : : .* . . : : ::: : . : . : *. : : . . : .: .:. : . * : : : :: : .: : : . :: . . * :: : . : : : : : : :: : :. . . . . . . . ", "identical_positions": 8, "similar_positions": 92, "identity": "0.66%" }, { "cls_id": "homologset.agr.RGD:620638", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64445-1", "uniprot_id": "COX8A_MOUSE", "id": "Q64445-1", "name": "Cytochrome c oxidase subunit 8A, mitochondrial", "aln": "MSVLTPLLLRSLTGSARRLMVPRAQVHSKPAREQLGVLDITIGLTSCFVCCLLPAGWVLSHLESYKKRE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P80433-1", "uniprot_id": "COX8A_RAT", "id": "P80433-1", "name": "Cytochrome c oxidase subunit 8A, mitochondrial", "aln": "MSSLTPLLLRSLTGPARRLMVPRAQVHSKPPREQLGVLDITIGLTSCFVCCLLPAGWVLSHLESYKKRE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10176-1", "uniprot_id": "COX8A_HUMAN", "id": "P10176-1", "name": "Cytochrome c oxidase subunit 8A, mitochondrial", "aln": "MSVLTPLLLRGLTGSARRLPVPRAKIHSLPPEGKLGIMELAVGLTSCFVTFLLPAGWILSHLETYRRPE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *******.***.**** ****::** *.. :**::::::******* ******:*****:*:: *", "identical_positions": 45, "similar_positions": 17, "identity": "65.22%" }, { "cls_id": "homologset.agr.RGD:620639", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y1A7-1", "uniprot_id": "Q9Y1A7_DROME", "id": "Q9Y1A7-1", "name": "", "aln": "-------MARVQASDSLIPRQVFEVP---------------PAEPNNSTADSG-SQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSG-SIGQSLIVWVLSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIYLLKPFWP-SCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFD----GNTEH-WDN--PFSGGLQDPGY-IALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYMITNIAYFSVLSPDEILSS-DAVAVTFGDKMLG--YMSWIMPFAVACSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTP----VPSLIFLGVLTLLLLFI-EDVYVLIN-YVSYVEALFTLISVSGLLWMRYKQP----KTERPIKVNLALPIIYLIVCLFLVIFSCTQT----------PYVVGIGTIIILSGIPVYYL--TIHKPVKWLADTSQAINLWCSKFFICMPNQEKFD------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB75-1", "uniprot_id": "Q9VB75_DROME", "id": "Q9VB75-1", "name": "", "aln": "-------MPAADELQSPSSEMVLLTPSSGNPPSSIAQPAANPAEKAQCREGSAESDSSRVVIKKQLGLLEGVAIILGIIFGSGIFVSPKGVIREVE-SVGASLVIWVLCGLLSMIGALCYAELGTAIPKSGGDYAYIFEAYGSLPAFLYLWDAMMIFVPTTNAIMGLTFASYVLEPFFGGACEIPKIALQLLAAITICFLTYLNSYYMKVTTKMQNVIMFTKIAALVLIILVGLVWMMM----GNVEN-FTR--PFDNTETDPGK-MSVAFYSGIFSYAGWNYLNFMTEELRDPYRNLPRAIYISLPLVTGIYVLANVAYLAVLSPSEMIAS-NAIAVTFGDKILG--VFSLIIPLMVAISAFGGLSVHIMTSSRICFVGARNGHMPAILSHISVKSYTP----LPSLVFLCFLSIVMLVV-SDVYVLIT-YASIVESFFIMLSVSAVLYFRYTRP----CMERPIKVAMWIPALFVIVCAFLVVVPIYVA----------PYEVGMGVLITIIGIPFYYVGVVWKNKPKWVQSTIDSVTFTCQKLFMSAK-EEKED------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9Z127-1", "uniprot_id": "LAT1_MOUSE", "id": "Q9Z127-1", "name": "Large neutral amino acids transporter small subunit 1", "aln": "-------MAVAGAKRRAVATPAAAAAEEER------QAREKMLEARRGDGADP--EGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG-SPGLSLVVWAVCGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPVFP-TCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFIQMGKDMGQGDASN-LQQKLSFEGTNLDVGN-IVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTNQMLTS-EAVAVDFGNYHLG--VMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSVLSMIHPQLLTP----VPSLVFTCIMTLMYAFS-RDIFSIIN-FFSFFNWLCVALAIIGMMWLRFKKP----ELERPIKVNLALPVFFILACLFLIAVSFWKT----------PMECGIGFAIILSGLPVYFFGVWWKNKPKWILQAIFSVTVLCQKLMQVVPQET---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63016-1", "uniprot_id": "LAT1_RAT", "id": "Q63016-1", "name": "Large neutral amino acids transporter small subunit 1", "aln": "-------MAVAGAKRRAVAAPATTAAEEER------QAREKMLEARRGDGADP--EGEGVTLQRNITLINGVAIIVGTIIGSGIFVTPTGVLKEAG-SPGLSLVVWAVCGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPVFP-TCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFIQMGKDIGQGDASN-LHQKLSFEGTNLDVGN-IVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTNQMLTS-EAVAVDFGNYHLG--VMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTP----VPSLVFTCVMTLMYAFS-RDIFSIIN-FFSFFNWLCVALAIIGMMWLRFKKP----ELERPIKVNLALPVFFILACLFLIAVSFWKT----------PLECGIGFAIILSGLPVYFFGVWWKNKPKWILQVIFSVTVLCQKLMQVVPQET---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01650-1", "uniprot_id": "LAT1_HUMAN", "id": "Q01650-1", "name": "Large neutral amino acids transporter small subunit 1", "aln": "-------MAGAGPKRRALAAP---AAEEKE------EAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAG-SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFP-TCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGK----GDVSN-LDPNFSFEGTKLDVGN-IVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSS-EAVAVDFGNYHLG--VMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTP----VPSLVFTCVMTLLYAFS-KDIFSVIN-FFSFFNWLCVALAIIGMIWLRHRKP----ELERPIKVNLALPVFFILACLFLIAVSFWKT----------PVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQET---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKC2-1", "uniprot_id": "Q9VKC2_DROME", "id": "Q9VKC2-1", "name": "", "aln": "-------------MTDRYANGVTTSLVEPT------NGCAAPGNPNPADGEEK------IVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTE-SVGSSLLIWLTCGILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALSFAHYAVKPFFP-ECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLYYMAT----GELEN-FRN--PWEG-IYTARN-IGYAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIWIAMPLVTSIYVLVNLAYFAVVNKPEMLSS-LAVAVTFGNRVFG--PLAFMVPIFVALSTFGGVNGVLFTSARLFATGAQEGHLPKFFQLFHVKQQTP----IPSLIFTCLMSLLMLLT-DNVYQLIN-YFSSVLWLSVVASIAGMLWLRHKRP----DLPRPIKVHLALPITFMVSCVTLVLLPNLEE----------PQNLLIGIGITLAGIPFYYAFIARKKKPKCYGRLSNSVVEICRAIFNTTIIESNEAIN----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50276-1", "uniprot_id": "MUP1_YEAST", "id": "P50276-1", "name": "High-affinity methionine permease", "aln": "MSEGRTFLSQLNVFNKENYQFSSSTTKKEVS-----NSTVDADNGASDFEAGQQFATELDQGEKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCG-SVGLALIMWAVGAIIAISGLYVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNSINTAIMFLTAADT---EVTKWNQRGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGGGLKDGYQSHNFRN--AFEGTETATAYGIVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVFGG-QAKRAAAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQHFIVCTVTILAPPP-GDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVTGFFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYYVVWAQLLPRWGHYKLVSKDVLGEDGFWRVKIAKVYDDTIGDVDTQEDGVIETNIIEHYKSEQEKSL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38734-1", "uniprot_id": "MUP3_YEAST", "id": "P38734-1", "name": "Low-affinity methionine permease", "aln": "-MEPLLFNSGKANPSQDVFIDVEVGDITTKYGSTNTGSFSSMDTVEAQAIKAETARFMEVPQGRHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFGV----TDDSWSKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTLFFYKSTGQVAWDLPVTQVEKDSLLSVSS-IATAFISSFFCFSGWDTVHTVTSEIKNPVKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHK----NEVPEIRASTFGVLAIITLSLYMLMAPFFADPSLNRVGFLPPYQIMSLLVIVAC---FFFWLVKFVLLPKFFHYKLLPKITYLHDGLIVTEWVKKPCLC----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: ::. : :: . :.*:*:* .. : . : :* . :: * : *:*: *.:.** :: : :: . .: . : . : :. : . :: :: : : : *: : .: * : * .. : *: * ::.: *:. :: *: :* :.* : :: . * : *:**: .: ::::: :. : :* . :. * ..: : : .*: ::* :* . : : :: : : : . : .:: : *:. :: . * : : . : ", "identical_positions": 30, "similar_positions": 127, "identity": "5.11%" }, { "cls_id": "homologset.agr.RGD:62064", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23944-1", "uniprot_id": "ADA1D_RAT", "id": "P23944-1", "name": "Alpha-1D adrenergic receptor", "aln": "MTFRDILSVTFEGPRSSSSTGGSGAGGGAGTVG----PEGGAVGG----------VPG-ATGGGAVVGTGSGEDNQSSTGEPGAAASG-EVNGSAAVGGLVVSAQG--VGVGVFLAAFILTAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLG-FWAFGRTFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDE--RFCGITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRIHCR-------------------GAATSAKGYPGTQSSKGHTLRS-------------------------------------SLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLG-SLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRR--LWAVYGHHWRASTGDARSDCAPSPRIAPPGAPLALTAHPGAG--SADTPETQDSVSSSRKPASALREWRLLGPLQRPTTQLRAKVSSLSHKIRSG-ARRAETACALRSEVEAVSLNVPQDGAEAVICQAYEPGDYSNLRETDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97714-1", "uniprot_id": "ADA1D_MOUSE", "id": "P97714-1", "name": "Alpha-1D adrenergic receptor", "aln": "MTFRDILSVTFEGPRASSSTGGSGAGGGAGTVG----PEGPAVGG----------VPG-ATGGSAVVGTGSGEDNQSSTAEAGAAASG-EVNGSAAVGGLVVSAQG--VGVGVFLAAFILTAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLG-FWPFGRTFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDE--RFCGITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRIHCR-------------------GAATSAKGNPGTQSSKGHTLRS-------------------------------------SLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLG-SLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRR--LWPSLRPPLASLDRRPALRLCPQPAHRTPRGSPSPHCTPRPG--LRRHAGGAGFGLRPSKASLRLREWRLLGPLQRPTTQLRAKVSSLSHKFRSGGARRAETACALRSEVEAVSLNVPQDGAEAVICQAYEPGDLSNLRETDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25100-1", "uniprot_id": "ADA1D_HUMAN", "id": "P25100-1", "name": "Alpha-1D adrenergic receptor", "aln": "MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGG----------VPGGAGGGGGVVGAGSGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQG--VGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLG-FWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVPPDE--RFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCR-------------------GAATGADGAHGMRSAKGHTFRS-------------------------------------SLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLG-SLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEMQAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVEAVSLGVPHEVAEGATCQAYELADYSNLRETDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24563-1", "uniprot_id": "DOPR2_DROME", "id": "Q24563-1", "name": "Dopamine receptor 2", "aln": "MVDDNGSSPEVEGAEGAGAPLLALLRVDGLNQTQTRSPSPSFFGSYNISEDVYFYFNGLPTSTELVLNATTSATSATLSPAMVATGGGGTTTPEPDLSEFLEALPNDRVGLLAFLFLFSFATVFGNSLVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAISFPAIVWWRAARDGEMPAYKCTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKIGTKQVLMASGELQLTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTSTPEEPDDEPLSALHNNGLARHRHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVNLLSGFCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLLCMCCPRKIRR------------------------------------------------------------------------------------KYQPTMRSKSQRFATRRCYSTCSLHG-----IQHVRHNSCEQTYI----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : * .**.. .:. : .. . .. .*. . * . . *:.: :. . : : ::..* .. . :. :: : . **: .** * : :* ** ****:* :*:*:*.*****..***** *:. .*:**** *** * ** :**:* ::*** .*****.**.**:*** .: ..:.** ** ::**.::* :* : .:*. .:: *: . : * :**. ** :***. *****: *:*. ***:* .* ****: * *: :.*: * :: : *.. .. * . ::.* : *** :* **::********.**:***::**:***.* *. : :: .* * :: ***::***:**:**.* **:*:***:*** * *: ** .:: * : ::*. ::*: :. * :: .* . ", "identical_positions": 162, "similar_positions": 152, "identity": "25.16%" }, { "cls_id": "homologset.agr.RGD:620640", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A087X1C5-1", "uniprot_id": "CP2D7_HUMAN", "id": "A0A087X1C5-1", "name": "Cytochrome P450 2D7", "aln": "--------------MGLEA---LVPLAMIVAIFLLLVDLMHRHQR---WAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPAPIYQVL-GFGPRSQGVILSRYGPAWREQRRFSVSTLRNLGL-----GKKSLEQWVTEEAACLCAAFADQAGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEE-SGFLREVLNAVPVLPHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAKKEKAKGS------PESSFNDENLRIVVGNLFLAGMVTTSTTLAWGLLLMILHLDVQRGRRVSPGCPIVGTHVCPVRVQQEIDDVIGQVRRPEMGDQAHMPCTTAVIHEVQHFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWKKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVAAGQPRPSHSRVVSFLVTPSPYELCAVPR------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10635-1", "uniprot_id": "CP2D6_HUMAN", "id": "P10635-1", "name": "Cytochrome P450 2D6", "aln": "--------------MGLEA---LVPLAVIVAIFLLLVDLMHRRQR---WAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQIL-GFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGL-----GKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEE-SGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGN------PESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQR------------------RVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64680-1", "uniprot_id": "CP2D4_RAT", "id": "Q64680-1", "name": "Cytochrome P450 2D4", "aln": "--------------MRMPTGSELWPIAIFTIIFLLLVDLMHRRQR---WTSRYPPGPVPWPVLGNLLQIDFQNMPAGFQKLRCRFGDLFSLQLAFESVVVLNGLPALREALVKYSEDTADRPPLHFNDQS-GFGPRSQGVVLARYGPAWRQQRRFSVSTFRHFGL-----GKKSLEQWVTEEARCLCAAFADHSGFPFSPNTLLDKAVCNVIASLLFACRFEYNDPRFIRLLDLLKDTLEEE-SGFLPMLLNVFPMLLHIPGLLGKVFSGKKAFVAMLDELLTEHKVTWDPAQPPRDLTDAFLAEVEKAKGN------PESSFNDENLRVVVADLFMAGMVTTSTTLTWALLFMILRPDVQC------------------RVQQEIDEVIGQVRRPEMADQARMPFTNAVIHEVQRFADILPLGVPHKTSRDIEVQGFLIPKGTTLIINLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPAGQPRPSNYGVFGALTTPRPYQLCASPR------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q95078-1", "uniprot_id": "CP18A_DROME", "id": "Q95078-1", "name": "Cytochrome P450 18a1", "aln": "MLADSYLIKFVLRQLQVQQDGDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSE-KHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRR--EEFTGRPDTPFMQTLNGYG------IINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNN-IRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMR------------------RVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :. :* ** *:: * : **** * :* ** :. : * :* ::*.:** :*. .**:.. :**.: *: :.** : : *:* .: * *::**** ..:*::*: **:.::: : *. : . : * *. . ::. **.***.** . **. :**:* *: * :: :. . . : .. : *. .*: : : :::: :*: ::** : ***.: :*.: ****.. :.. ::*:* *: :** *** * .*** * ::*: . . ***:*:*:*:*: * * : * :* * :.* * : ..*:**...* .:**:*::*: ** *: :* :.** * :*:** .*:*.:*:*::*:. * * *:**..*** ***: **********:.::: *.:::. *** ** .. :* .:::* * ", "identical_positions": 149, "similar_positions": 168, "identity": "26.33%" }, { "cls_id": "homologset.agr.RGD:620641", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QX67-1", "uniprot_id": "DAP1_RAT", "id": "Q9QX67-1", "name": "Death-associated protein 1", "aln": "MSSPPEGKLETKAGHPPAVKVAGIRIVQKHPHTGDGKEKKD-KDDQEWESTSPPKPTVYISGVIARGDKDFPPAAAQVAHQKPHASMDKHVSPR--TQHIQQPRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XC8-1", "uniprot_id": "DAP1_MOUSE", "id": "Q91XC8-1", "name": "Death-associated protein 1", "aln": "MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDGKEERD-KDDQEWESTSPPKPTVFISGVIARGDKDFPPAAAQVAHQKPHASMDKHVSPR--TQHIQQPRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51397-1", "uniprot_id": "DAP1_HUMAN", "id": "P51397-1", "name": "Death-associated protein 1", "aln": "MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKD-KDDQEWESPSPPKPTVFISGVIARGDKDFPPAAAQVAHQKPHASMDKHPSPR--TQHIQQPRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9N1-1", "uniprot_id": "DAP1A_DANRE", "id": "Q9I9N1-1", "name": "Death-associated protein 1 homolog", "aln": "MSSPPKEKTETRAGHLPAVKAGGMRIVQKHQSAIEVPDKKDDKDSTEYETVIPPKLPVVVSGVVTKGDKDFTPAAAQVAHQKPVPSAQKLPAGQHLNQHIHQPRK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****: * **:*** ****..*:****** : : :::* **. *:*: *** .* :***:::*****.*********** .* :* : : .***:****", "identical_positions": 59, "similar_positions": 25, "identity": "56.19%" }, { "cls_id": "homologset.agr.RGD:620642", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55007-4", "uniprot_id": "RGPA1_RAT", "id": "O55007-4", "name": "Ral GTPase-activating protein subunit alpha-1", "aln": "MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENADSIDLKQFFDQHFSHIYYVFFENFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGNSLKIRREGVRLFLLWLQALQDNCSKEQLWMFSCLIPGFSAPQ-----SEYGPRTLDNLINPPLNLQ------------ETQVTIEEVTPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNK--ENQERGFSFLFSHFKKFYLPYIFPNLCKENSLYHPVLDIPQVRPKPHYVMVKKDAETNETIYCTKEPFIQARVIVIRWLVSFWLEPKPHSGPNIPGMEGEVLPKNIQRAAASLVSREESKNDTVDKADKT--AEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFLLPIC---EAAAMRKVVKVYQEWIQQEGKPLFMQEPEETVITSSDIPCSENVTDHDISIEDGEKREEENGTNISEHVRNSTWTKNGSYQEAFH-VSEEATEQNIQAGTQAVLQVFIINSSNIFLLEPAN-----------EIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMSSQAFLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELATEWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGWSRDQPGQ-APMRQRSATTTGSPGTEKARSIVRQKT---VDID-----------------------------------------------DSQILPRSTRVRHFSQSEDTGN---EVFGALHEEQ--PLPRSSSTSDILEPFTVERAK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNKEDTSPKLPPLNSETGGSSANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPVDDPGVPSEWTSPASAGSSDLMSSDSHSDSFSAFQCEGRKFDNFGFGTDIGIPSSADVDSGSGHHQSTEEQEVASLTTLHLDSETSSLNQQAFSAEVATVTGSESASPVHSALGSRSQTPSPSTLNIDHMEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNAIMDPEIHAQVFDYLCELWQNLAKIRDNLGISADNLTSPSPPVLIPPLRILTPWLFKATMLTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCS-PQFFSLGLPGATMLIMDFIIAAGRVASSAFLN--APRVEAQVLLGSLVCFPNLYCELPALHPSTPDIAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHES----------------------------HHPQIKEALNVICVSLKFTNKTVAHVACNMLHMLVHYAPRLQTYQPDSPLKIIQILIATITHLLPSTEASSYEMDKRLVVSLLLCLLDWIMALPLKTLLQSVHSTGAENEKTEKSVLNCIYKVLHGCVYGAQSFSHPKYFPISLSDLASVDYDPFMHLESLREPEPLHSPDSERSSKLQPVTEVKTQMQQGLISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDN---------HYSESTELSPELFDSPNIQFFVLNNTTLVSCIQIRSEESVPGGGLAAGLVSANSNVRIIVRDLSGKYSWDSAILYGPPIVSGLPEPTSFILSMS---------------YQEKPE--------------------EPPTSNECLEDITVKDGLSLQLR------RFRETVPTWSTIREEEDVLDELLQYLGTTSPECLQRTGISLNVPAPQPVCISEKQENDVINAILKQYTEEKEFVEKHFNDLN--------------------MKASEQDEPTPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKYSILTNIGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQKNKSTGLTTPYFATSTVEVIFHVSTRMPSESDDSLTKKLRHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRSTAINASRALKSLIPLYQNLYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHFPADADH-----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6GYP7-1", "uniprot_id": "RGPA1_MOUSE", "id": "Q6GYP7-1", "name": "Ral GTPase-activating protein subunit alpha-1", "aln": "MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFENFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGNSLKIRREGVRLFLLWLQALQDNCSKEQLWMFSCLIPGFSAPQ-----SEYGPRTLDNLINPPLSLQ------------ETQVTIEEVTPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNK--ENQERGFSFLFSHFKKFYLPYIFPNICKENSLYHPVLDIPQIRPKPHYVMIKKDAETNETIYCTKEPFIQARVIVIRWLVSFWLEPKPHSGPNIPGMEGEVLPKNIQRAAASLVSREESKNDTVDKVDKS--AEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFLLPIC---EAAAMRKVVKVYQEWIQQEEKPLFMQEPEDTAITCSDIPCSETVADHDSAIEDGEKREEENGTSTSEHVRNSSWTKNGSYQEAFH-VCEEATEQNIQAGTQAVLQVFIINSSNIFLLEPAN-----------EIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMSSQAFLQFQGKKSMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELATEWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGWSRDQPGQ-APMRQRSATTTGSPGTEKARSIVRQKT---VDID-----------------------------------------------DAQILPRSTRVRHFSQSEDTGN---EVFGALHEEQ--PLPRSSSTSDILEPFTVERAK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNKEDTSPKLPPLNSETGGNSANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPVDDPGVPSEWTSPASAGSSDLMSSDSHSDSFSAFQCEGRKFDNFGFGTDIGIPSSADVDLGSGHHQSTEEQEVASLTTLHLDSETSSLNQQAFSAEVATVTGSESASPVHSALGSRSQTPSPSTLSRAHIEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNAIMDPEIHAQVFDYLCELWQNLAKIRDNLGISADNLTSPSPPVLIPPLRILTPWLFKATMLTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCS-PQFFSLGLPGATMLIMDFIIAAGRVASSAFLN--APRVEAQVLLGSLVCFPNLYCELPALHPNIPDIAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHES----------------------------HHPQIKEALNVICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIHQPQSPLKIIQILIATITHLLPSTEASSYEMDKRLVVSLLLCLLDWIMALPLKTLLQPVHATGAENDKTEKSVLNCIYKVLHGCVYGAQSFSNPKYFPISLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQQGLISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDN---------HYSESTELSPELFESPNIQFFVLNNTTLVSCIQIRSEESMPGGGLAAGLVSANSNVRIIVRDLSGKYSWDSAILYGPPIVSGLPEPTSFILSMS---------------DQEKPE--------------------EPPTSNECLEDIAVKDGLSLQLR------RFRETVPTWSTIREEEDVLDELLQYLGTTSPECLQRTGISLNVPAPQPLCISEKQENDVINAILKQYTEEKEFVEKHFNDLN--------------------MKASEQDEPTPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKYSILTNIGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQKNRSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRSTAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHFPADADH-----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6GYQ0-1", "uniprot_id": "RGPA1_HUMAN", "id": "Q6GYQ0-1", "name": "Ral GTPase-activating protein subunit alpha-1", "aln": "MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFENFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGNSLKIRREGVRLFLLWLQALQNNCSKEQLWMFSCLIPGFSAPQ-----SEHGPRTLDNLINPPLNLQ------------ETQVTIEEITPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNK--ENQERGFSFLFSHFKKYYLPYIFPNICKENSLYHPILDIPQMRPKPHYVVIKKDAETNEAIYCTKEPFIKARVIVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNIQRAAASLVSREESKNDNADKTDRT--TEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFLLPIC---EAAAMRKVVKVYQEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTDHDISMEEGEKREEENGTNTADHVRNSSWAKNGSYQGALHNASEEATEQNIRAGTQAVLQVFIINSSNIFLLEPAN-----------EIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMPSQAFLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELATEWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGWSRDQPGQ-APMRQRSATTTGSPGTEKARSIVRQKT---VDID-----------------------------------------------DAQILPRSTRVRHFSQSEETGN---EVFGALNEEQ--PLPRSSSTSDILEPFTVERAK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNKEDMSQKLPPLNSDIGGSSANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNSIMDPEIHAQVFDYLCELWQNLAKIRDNLGISTDNLTSPSPPVLIPPLRILTPWLFKATMLTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCS-PQFFSLGLPGATMLIMDFIVAAGRVASSAFLN--APRVEAQVLLGSLVCFPNLYCELPSLHPNIPDVAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHES----------------------------HHPQIKEALNVICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIYQPDSPLKIIQILIATITHLLPSTEASSYEMDKRLVVSLLLCLLDWIMALPLKTLLQPFHATGAESDKTEKSVLNCIYKVLHGCVYGAQCFSNPRYFPMSLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQHGLISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDN---------HYSESTELSPELFESPNIQFFVLNNTTLVSCIQIRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWDSAILYGPPPVSGLSEPTSFMLSLS---------------HQEKPE--------------------EPPTSNECLEDITVKDGLSLQFK------RFRETVPTWDTIRDEEDVLDELLQYLGVTSPECLQRTGISLNIPAPQPVCISEKQENDVINAILKQHTEEKEFVEKHFNDLN--------------------MKAVEQDEPIPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQKNKSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHLPSDADH-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HQV3-1", "uniprot_id": "A0AC58HQV3_DANRE", "id": "A0AC58HQV3-1", "name": "", "aln": "MFSKKPHGDVRKSTQKVLDPKKDVLTRLKHLRIVIENAESAELKHLFEQNYSHIYYVFFENFVTIEVNLKQKGHKSQREELDSILFIFEKILQLLPERIQGRWQFHSIGLILKKLLHTGNSLKIRREGVRLFLLWMQALQHNALREQLWIFACLIPGFPAPQ-----SELGPRTLDNLISPPLNLQ------------EPQVTPEEISPLVPPQSGDKSQEDLTGYFLEALLKYMVNQAKSLEWKCK--ENHEKGFAFLFANFKKYYLPHIFPNFSKETSLYNPILEVPPMRPKPYYMVVKRDPETNEALYCTKENFLNARVIFIRWLVSFWLEPRSNTGTQIPGMEGENVPKNIQRAAAGLAARGEDGGPRQDSLDGGGIGEPEQSHSNTSTLTEREPSSSSLCSMDEEHLTDIEVVRRVLCSSRTNVNFITEIFRQAFLLPMC---EAAAMRKVVRVYQEWISQQDKPVFMRQPEEERFTG----------QLDSTHEQRADKDEEEDVGLTVSVRNPNWSRSKS----------SDSEYNVHAGVQATLQVFITNSSNVFLLEAAN-----------ELKSLLEEHVDMCKRVLNIYRSLVMHETMNQKTWEQILLVLLRVTECVMKRP--PSIMPHGKKSSTLSGRLAGAIFQTLIVAWIKGNLNVYISRELWDDLLSVLSSLTCWEELVTEWSLTMETLTKVLARNLYSLDLNELPLDKLSEQKQKKHKGKGGIHEGQKITVDRSFSKGWSRDPPGQAAAMRQRSATTAGSPGIEKARSIVRQKT---VALRSCSTGDSLLSSAFIRSAKSAPVLIHPVHPLLPDSVLTPLADELSDLEEPPMIQRGPRNRHCSQSEETPT--SEVFSASGELEQPPLPRSSSASDIMEPFIAERAKGALPVSDSPSHSPHFTATTTTIEFPHSSPNPQQLTDPQQLPDSQASLEVAESIYDHLCQMPGQQPPFIPDWSCPAAASANQPEGEAEEDVFSAFREFCHRENVKMEAGADLKQVQFEGDWALEWDREMEQSEKSLYECLEECDWDLSVSPQPAEDGKGAQLQRQDATDRASESEVSPQASHGPMLSNIDHKKRHSSAVHVSFRPSTESVLFHNPLDPKEAHWKTRLRRLGHFSSHSVGAKGVGEGVTCCEVVERERGSISGARRGRLGRPTLRPRGSRSRSQESGCSPSRQQQVALLGGVYKSMVHALSKPKGQAASPQRHSKSPATEAHLKDLYASVMGYFGRKTSANKDELTPKMRPMSNDAGSSNPNVSDLMDEFIQERLRARGNSGMTRRGSSPGSLEIPKDLPELLNRQNATRPADDPGVPSEWTSPASASGSDLISSDSQSDSFNAFQYDS-KFENFSFPPETCALASADQDSLSGTGQTAEEQELSSLTTLHIDSETSSLSQHGLSADTVTITGSESASPMHSLGGSRSQTPSPATLTAEHVQHKELQLDEKMHHSVLQTPDDLETSEFPTEDCSVMAGGTLTGWHADVATVMWRRMLGILGDVNYIKDPEIHAQVFDYLCELWQNLAKIRDNLGISLDNQSSPPPPDLIPPLRILTPWLFKATMLGERYKQGKLHAYKLICKIMKRRQDVSPNSDFLTHFYNIMHCGLLHQDQDIVNTIIKHCS-PRFFSIGLPGATMLILDFIVAASRVTACSSLN--APRVEAQILLGSLVCLPNLYNELPALHPTTADIIMTKFTDVKEHIIKHILTSARDEPSAPARCVALCSLGIWLCEELVHGT----------------------------QHPQIKEALNVICVTLKFSNKNVALVASDILHLLINYVDELEKFPPNTPKKIVEVLIATITYLLPATESSPHELDKRLVVSLLLCLLDWVMALPPKTLLQPVQG-ASDKEKTDKSVLSCIYKVLHGCVYGAQSFSNPSYFPIHLSDLSSPDYDPFLLLENLKEPEPLHSPDSERSSKLQPVTEVRSRIQQGLVSVAARTVISHLVNHLGHYPMSGGPATLTSQVCENQDN---------PYSESADLTPELFDAPNLQFFVLNGTTLLSYLQIRAEDGLPGGGMSAGLTTTNACVRVIVRDISGKHSWDSAVLYGPPHCITPSQTLHLYTSSNPRGEHNRDEDSLERGSQEEPEDGAFQESEEDLDEHEEAEVKEDEVEEEELEEEIEEEEVALELMAPQAKRRCREVIPNWDSLQDGEDSLDEMLQYLGYSSPECLQRTGGPLNIPAPPPNCVSEKQENDVINAILKQCAEEQDFTIHRGNELN--------------------MRAVVQQEPSPQRPQSAFYYCKLLLNILGMNSWEKRNSFHLLKKNEKLLRELKNLDSRQCRETHKIAVFYVAEGQEDKHSILSNTAGSQAYEDFVSGLGWEVNLTSHCGFMGGLQRNKSTGFTMPYFATSTVEVMFHVSTRMPPDSDDSLTKKLRHLGNDEVHIVWSEHSRDYRRGVIPTEFGDVLIVIYPMKNHMYSIQIIKKPEVPFFGPLFDGAIVDGTILPTVVRATAINASRALKSLIPLYQNFYEERARYLETIVQHHLEPTTFEDYAARVFCPAPFHYLPSEAERNAVIFLPLPKPPLENIGLTKVKGKGLKRK--------VFHASCEWLMPRESAGRKSSNAGRRERLSLANVTSC----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VB98-1", "uniprot_id": "Y5521_DROME", "id": "Q9VB98-1", "name": "Probable Rho GTPase-activating protein CG5521", "aln": "MFTKKSHADVKKSTAKLQDSKKDSASRLRHLRMILDNVELEESKCLFETNYSHVYFILYDTFIQAEANLKQKVHKAHREELDGSLWLLEKILCLLPELLARRWQCHSLSRIMAKLLHLGNSPKLRREGVRYFLLWYQTLGENAPGYVHAMYADLIPGLIVPQKGVVGPDTEFSASDFLTHPNMKADGGMASVFHDNAFSHPVQSSEVVALLPPSSSEKSAPPDPRDGLEVLLNSMVHTAACLRWRDNRAQKDHRAFAFLLQRFMDVFLPVFSPNFDVSCSIYNPRLDLPVMR----------------SINKKEEVMASCVVVLINWVSRFTHER-------------------------------------------------LLSHRLDCTLHIEDVDQVRLHGYQQG-----LIVRDVLYVNRENINFVHEVYRQAFLLNFTSKPQIEAIRTAIAVYRDWMTGETPPPFLLEPND----------------------DPPPPSNAGGTPRSQRLRTPSYVGAIAG---------SKDQLVVRAGRQNVLQVFVTNAANVFLVNTANLNICFPTRSRSYRSTPLEEQTEICKKVLNVYRTMVMNTEMDTRTWEQLLMVLLQVTSIVLHQN-QHTLPSGTNKSATLGGILGSAIFQTLIVTWIRAHTKVPVNVLLWEKFLNVLQSLTHREELIIEWNKTIQTLTRVFSRYTYGINLLDLPLDRVAESRAEKRRRIG---------------------------SVWQGSGSNSAANGGSAASAAISQNRQRES------------------------------------------------------LAESSSSRSEETSSQVPLPN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HPRPHHQHTQSQGGTGHGTRPIPLTPMLSRSYSEGSLASAARSSRIRRRRAATPKPKALQPSQLAENRINPQDLRRAMSLDSLARKGDAEETDSYQE-----------------------------------------------------------------GDNESGAGSRSPSPTASSG-----------IEGGSIKDAQLQIDASLDDANSGSYGSGSNSGSISGRRCIILGGSAEGWHPDSTSIMWKRMLGALGDVNRIPKADLHAQVFMHLLEMTQNLIKIKQNQGISTDNQNTQPMPPLVPPIGIVAPWCYGSLSLDRSFKKGKLWALQLLCSLAIQG---AVNMQQLPLFYHALHQLLTGEDRDLIYAILKHLEGPRLLSLLLPGHTLLLLDLVHASAILLTSLEVSRSTPRAEVAALLGSLLCYPSSLLTRSVLQPTPQKFELMECSDLQDHILNIVLRCARREPSAKARCIALSQLGQWLLMRLSQPLPASNSGRANLFQQAVPHHKDVHPKASSVYNPRIKEVLQVLLQALQFKHHTIAIVAVDSLKLCAERGRQLAAIERVPQLIITAICKALEIQSVTKPKDS----DKVVLTSLMLCLGEFCMAIPAPIMLTPFNE-------QGDTLVLQVLRVLLQVASGAPRHER-------VKLTADDDFDMHIAHDDLQGDGRLPEATYQTSETIQKCITA--------IKLCAKAVSMHLVTHIGHFPMGIGASRLSSMVEEQDDIGNAAYGGQVETRRDSVELPSVVSAQNMQLFMLNSGLVASFIELP-TLKLPGGGITAGLVTADKQVRVLMRDLNGKACWDASILYSEPRNAEEPPKTTPKIQHS------------------------------------------QPLDSMATSMVTHTPSPRHTLR-----HRPAGVLPLAKDMAPDLDQLDDMLAYIGHTSPECVAPTVSQLNAPTASP--LSGNQEAQAISVILNQRLLEQEFVTHSTQAPSPALRHASSNSSLQQPDQRSLHSTTASFDSLPTRTEMPFQYCRLLFSHLGLAGWERRSRTHLLQRSEKLMRELRNVDLQKCRETHKMAVIYVAAGQEDKGSILRNTSGSSTYEMFVSALGWEIDLETHNGFLGGLPR-QGCGATAPYYATPFLEVVYHVATRMPSDSSEAMLLKTRHLGNDEVHIVWSEHNRDYRRDILPTEFCDVLIVVYPLRNGLFRVTVNRKPEVPWFGPLANESVVSGACLATLIRATAINASRTKRAALPLYQQFYEERNRSLDSVSSRYKESTTFEDFASRIYNPMPLSTLGTLRESNASSSAAPLASALLDHNRASVKGWVQASIDSGPIMGIAPSASAGSTAAMEAATGMSSASPRGPRKLGAPFKSVTKKHSLQHIAVGGGAGAGGDTPPESPTLPQRRFK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**.*.**:*** *: *.*** :**:***::::*.: : * :*: ::**:*:::::.*: *..**** **::*****. *:::**** **** : *** **:. *: **** *** *:****** **** *:* .*. ::: ****: .** .: : * * * :. : . * .*: .*:**.*.:*. . **.**: :* . .*.*: : ::..:.*:**: .* . :** : **: . *:*:* *::* :* :: .:* : .. *:.*.*: * * ** .** .: .. * . :: :** *: .* *:**: *::****** : : *:*..: **::*: : * *: :*:: : .: .. : :*...: : . : ::** * .****: *::*:**::.** .. *:*:.::**::**:** :*:: *: :****:*:***:**. *:: : :*. **.* *...:******:**:.: :* :. **:.:*.**.*** *** **. *::***:*::* *.::* :****:::*.: :*:: * .: * *.:.:.: * . * : : *: : ... * . *.:. . : ..: * . . . : :: . . : :* . . . : * . : .: : : * .* .:** .: .: : :**.*.** * : ::. :**:* .:..: : .. . * : .:: **: ***.* :::**:**** ***** * ..::***** :* *: *** **::* *** ** .: . * *:**: *::** : : * :*:*** * :*:*. : : * : *. **: :* * *:*:: :*:** . *:::*: *** *:*::*:: *:. : :. :. :**.*. *****:* *. . *:*. .. : : :*::: *:: :* .** ***. ***:**..** *: .* : :*:***.*:*: :*:*.::.:* ** : *:: . .* . * : * :. .: * ** ::.**:*** :: **:* :* ..: .::: : :** . ** ... :. :. *:* .: :.*: * .. : *..:* . :.:.*::* ***.*:**:**. *.: *:* * *:.* ..: *.:..: *:*:*:**. : * ::: :****::***.::: **:::**:.** .**:::**. * . . . .. . : * .:* . : * **::* *:* :****: * ** *:. * :* :** :.*..**:* *::*. : : . : . :. * :.: .* **:**:. **: .*::* ***::.***:***:*:* ::******:**:*** ***** *** * .**.:** **:.****::* .* **:*** : :. * * **:**. :**::**:****.:*.::: * ***************.*****.::**** *****:**::* :: : : :*****:**** : ::*.* *. ::*:*******: :: :****::**** * *::: .:: *.*****:*:::: * * : : : ", "identical_positions": 595, "similar_positions": 603, "identity": "22.18%" }, { "cls_id": "homologset.agr.RGD:620643", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D2N9-1", "uniprot_id": "VP33A_MOUSE", "id": "Q9D2N9-1", "name": "Vacuolar protein sorting-associated protein 33A", "aln": "--------------------MAAHLSYG--RVNLNVLREAVRRELREFLDKCAGS---KAIVWDEYLTG----PFGLIAQYSLLKEHEVEKMFTLKGSRLPAADVKNI----IFLVRPRLELMDIIAENVLSED-----RRGPTRDFHILFVPRRSLLCEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLMTLQALYG-TIPQIFGKGECARQVANMMVRMKREFTGS-----------QNSVFPVFDNLLLLDRNVDLLTPLASQLTYEGLIDEIYGIQNSYVKLPPEKFAPK--KQGGGSGGKDLP--------TEAKKLQLNSAEELYAEIRDKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVS-QLPHMQAARGSLANHTSIAELIKDVTTSEDFFDK---LTVEQEFMSG--IDTDKVNSYIEDCIAQKHPLIKVLRLVCLQSVCNSGLKQKVLDYYRREILQTYGYEHILTLNNLEKAGLLKAQTGGRNNYPTIRKTLRLWMDD----------------------VNEQNPTDISYVYSGYAPLSVRLAQLL------------------SRP-GWRSIEEVLRILPGPHFEERQPLPTG-----------LQKKRQPGEN---------RVTLVFFLGGVTFAEIAALRFLSQLEDG---GTEYVIATTKLMNGNSWIEALMEKPF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63615-1", "uniprot_id": "VP33A_RAT", "id": "Q63615-1", "name": "Vacuolar protein sorting-associated protein 33A", "aln": "--------------------MAAHLSYG--RVNLNVLREAVRRELREFLDKCAGS---KAIVWDEYLTG----PFGLIAQYSLLKEHEVEKMFTLKGSRLPAADVKNI----IFLVRPRLELMDMIAENVLSED-----RRGPTRDFHILFVPRRSLLCEQRLKDLGVLGSFIYREEYSLDLIPFDGDLLSMESESAFKECYLEGDQTSLYHAAKGLMTLQALYG-TIPQIFGKGECARQVANMMVRMKREFTGS-----------QNSVFPVFDNLLLLDRNVDLLTPLASQLTYEGLIDEIYGIQNSYVKLPPEKFAPK--KQGGG-GGKDLP--------TEAKKLQLNSAEELYAEIRDKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVS-QLPHMQAARGSLANHTSIAELIKDVTTSEDFFDK---LTVEQEFMSG--IDTDKVNNYIEDCIAQKHPLIKVLRLVCLQSMCNSGLKQKVLDYYKREILQTYGYEHILTLNNLEKAGLLKAQTGGRNNYPTIRKTLRLWMDD----------------------VNEQNPTDISYVYSGYAPLSVRLAQLL------------------SRP-GWRSIEEVLRILPGPHFEERQPLPTG-----------VQKKRQPGEN---------RVTLVFFLGGVTFAEIAALRFLSQLEDG---GTEYVIATTKLINGSSWLEALMEKPF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96AX1-1", "uniprot_id": "VP33A_HUMAN", "id": "Q96AX1-1", "name": "Vacuolar protein sorting-associated protein 33A", "aln": "--------------------MAAHLSYG--RVNLNVLREAVRRELREFLDKCAGS---KAIVWDEYLTG----PFGLIAQYSLLKEHEVEKMFTLKGNRLPAADVKNI----IFFVRPRLELMDIIAENVLSED-----RRGPTRDFHILFVPRRSLLCEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLMTLQALYG-TIPQIFGKGECARQVANMMIRMKREFTGS-----------QNSIFPVFDNLLLLDRNVDLLTPLATQLTYEGLIDEIYGIQNSYVKLPPEKFAPK--KQGDG--GKDLP--------TEAKKLQLNSAEELYAEIRDKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVS-QLPHMQAARGSLANHTSIAELIKDVTTSEDFFDK---LTVEQEFMSG--IDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGLKQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMDD----------------------VNEQNPTDISYVYSGYAPLSVRLAQLL------------------SRP-GWRSIEEVLRILPGPHFEERQPLPTG-----------LQKKRQPGEN---------RVTLIFFLGGVTFAEIAALRFLSQLEDG---GTEYVIATTKLMNGTSWIEALMEKPF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ID82-1", "uniprot_id": "A0A0R4ID82_DANRE", "id": "A0A0R4ID82-1", "name": "Vacuolar protein sorting-associated protein 33A", "aln": "--------------------MASHLFCG--RVNLNILREAARKDLREFLDKCSGS---KAIVWDEYLTG----PFGLIAQYSLLKEHEVEKMFTLKGGRIPSAAVKNI----VFFVRPRLELMDIIAENVSSED-----KLQP-REFHILFVPRRSLLCEQRLKEKGVLNSFTNIDEYILDLIPYDGDLLSMESESSFRECYLENDQTSLYHAAKGLMTLQALYG-TIPQIFGKGECARHVANMMLRMKREFAGS-----------HTQILPVFDTLLLLDRNVDLLTPLATQLTYEGLIDEIFGITNGYVKLPPEKFAQK--KQGEG--GKDLP--------TEPKKLQLNSAEELYAEIRDKNFNAVGAALSKKAKIISAAFEERHNAKTVGEIKQFVS-QLPHMQAARSSLANHTSIAELIKDITTSEVFFDS---LTVEQEFMTG--VDTDKVSTYIEDCIAQKDPLIKILRLVCMQSVCNNGLKQKVLDYYKREILQTYGYKHILTLKNLEKVGLLKPQSTMRNNYPTIRKTLKLWMED----------------------ANEQNPNDISYVYSGYAPLSVRLTQVL------------------ARP-GWRSIEEVLKMLPGPHFEERQQVPTG-----------LHKKRQPGEN---------RTTLVFFLGGVTYAEIAALRFLSHMEDS---GTEYIIATTKLINGTSWVKSLMDHPEENQQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y1I2-1", "uniprot_id": "VP33A_DROME", "id": "Q9Y1I2-1", "name": "Vacuolar protein sorting-associated protein 33A", "aln": "--------------------MFPHLKGHGQRVNLQLLQEAACRELLQQLDRIEGS---KVIVLDETMIG----PLDLVTRPKLFADRGIR-LLALKPELHLPREVANV----VYVMRPRVALMEQLAAHVKAGG-----RAAAGRQYHILFAPRRSCLCVSQLEVSGVLGSFGNIEELAWNYLPLDVDLVSMEMPNAFRDVSVDGDTSSLYQAAVGLVQLQRLYG-RIPKIYGKGEFAHRVWEHAKQLGRDERTL-----------YNGDKGVVDQLILLDRSIDLLSPLATQLTYEGLIDEFYGIRQNKLTLPAENFPSDGALPGGGGSGPRVEESQSLLGDTEKKTILLHSGEQLYAELRNKHFNEVTKLLARKAREIHVQMHATSQDKSVQEIKSFVENLLPQLMAQKKATSEHTAIAGLLHEQVNAVRFADD---LAAEQEFMVC--ADIDKPSAYIEDLIACRVELNRVLRLICMQCHAASGFKEKLLNHYKRELVHVYGLEVLLTISNLEKSGLLHLQTESR-AYSVLRKTLHLTVDD----------------------NVEIEPKDISYVHSFYAPLTARIVEHS------------------LKPLGWQTLKSQINNLPGPTFEDFQAQLVG-----------IGGRHTVTTVSEGSLLNVPRVVLVCFVGGCTFAEIAALRFLAAQEDN---NVEFLIATTKVVNKHSFLDSLMSS------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20795-1", "uniprot_id": "VPS33_YEAST", "id": "P20795-1", "name": "Vacuolar protein sorting-associated protein 33", "aln": "MNRFWNTKKFSLTNADGLCATLNEISQNDEVLVVQPSVLPVLNSLLTFQDLTQSTPVRKITLLDDQLSDDLPSALGSVPQMDLIFLIDVRTSLRLPPQLLDAAQKHNLSSLHIIYCRWKPSFQNTLEDTEQWQKDGFDLNSKKTHFPNVIESQLKELSNEYTLYPWDLLPFPQIDENVLLTHSLYNMENVNMYYPN-LRSLQSATESILVDDMVNSLQSLIFETNSIITNVVSIGNLSKRCSHLLKKRIDEHQTENDLFIKGTLYGERTNCGLEMDLIILERNTDPITPLLTQLTYAGILDDLYEFNSG-IKIKEKDMNFN------------------------------YKEDKIWNDLKFLNFGSIGPQLNKLAKELQTQYDTRHKAESVHEIKEFVD-SLGSLQQRQAFLKNHTTLSSDVLKVVETEEYGSFNKILELELEILMGNTLNNDIEDIILELQYQYEVDQKKILRLICLLSLCKNSLREKDYEYLRTFMIDSWGIEKCFQLESLAELGFFTSKTGKTDLHITTSKSTRLQKEYRYISQWFNTVPIEDEHAADKITNENDDFSEATFAYSGVVPLTMRLVQMLYDRSILFHNYSSQQPFILSREPRVSQTEDLIEQLYGDSHAIEESIWVPGTITKKINASIKSNNRRSIDGSNGTFHAAEDIALVVFLGGVTMGEIAIMKHLQKILGKKGINKRFIIIADGLINGTRIMNSIS--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : :: .. ..* * .: * : *: : . .:. :.: .*: :. : * . *: : * : : : : . : ::: :. * .:* :: : : :.* . ::. : : . . .* * . *.:: . *: ::: . : : : *::*:*. * ::** :**** *::*::: : .. :.: :.: . . :::: ::: :*. : * : *: : . . : ::* ***.**. * : : :**::: : . . : : . * * *:: : * . :* . ::***:*: . . ..:::* :: : ::. :* : : : .* : *:: :: : . *: :* : : : .: ::.:* .**: *:.: : :. :. * * . : . .: .*: *:** * .*** ::.* . . .::* : ::* :.:: ", "identical_positions": 71, "similar_positions": 205, "identity": "9.7%" }, { "cls_id": "homologset.agr.RGD:620644", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63616-1", "uniprot_id": "VP33B_RAT", "id": "Q63616-1", "name": "Vacuolar protein sorting-associated protein 33B", "aln": "MAFPHRLDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKLTLS--SNEQLCFLVRPR-----------------IKTMR----YIANLVNADKLAGRVRKYKIILSPQKFYACEMVLEEEGVYGDVSCDEWAFSLLPL----DVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYG----------IGRCTKMSYDLWRKLEEEEDSE-----------TKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSVDFG--------------------PEVTSSDKSLKVLLNAE-DKVFSEIRNEHFSNVFGFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIES-----LRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQASGDTLTAVENKVSKLVTDKAAG--KITD-AFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSG--AYVPLSCRIIEQVLDRRSWQGLDEVVRLLNCSDFAFT-------DMAKEDKASSESL----------------RLILVVFLGGCTFSEISALRFLGREKG-----YRFIFLTTAVTNSARLMEAMSEVKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59016-1", "uniprot_id": "VP33B_MOUSE", "id": "P59016-1", "name": "Vacuolar protein sorting-associated protein 33B", "aln": "MAFPHRLDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPALS--ANEQLCFLVRPR-----------------IKNMR----YIASLVNADKLAGRIRKYKVILSPQKFYACEMVLEEEGVYGDVSCDEWAFSLLPL----DVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYG----------IGRCAKMSYDLWRKLEEEEDSE-----------TKGRKPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSVDFG--------------------PEVTSSDKSLKVLLNAE-DKVFSEIRNEHFSNVFGFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIES-----LRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVESKVSKLVTDKAAG--KITD-AFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSG--AYVPLSCRIIEQVLDRRSWQGLDEVVRLLNCSEFAFT-------DTAKEDKASSESL----------------RLILVVFLGGCTFSEISALRFLGREKG-----YRFIFLTTAVTNSARLMEAMSEVKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H267-1", "uniprot_id": "VP33B_HUMAN", "id": "Q9H267-1", "name": "Vacuolar protein sorting-associated protein 33B", "aln": "MAFPHRPDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPALS--SNEQLCFLVRPR-----------------IKNMR----YIASLVNADKLAGRTRKYKVIFSPQKFYACEMVLEEEGIYGDVSCDEWAFSLLPL----DVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYG----------IGRCAKMAYELWRNLEEEEDGE-----------TKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSVDFG--------------------PEVTSSDKSLKVLLNAE-DKVFNEIRNEHFSNVFGFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIES-----LRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVESKVSKLVTDKAAG--KITD-AFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFGG--AYVPLSCRIIEQVLERRSWQGLDEVVRLLNCSDFAFT-------DMTKEDKASSESL----------------RLILVVFLGGCTFSEISALRFLGREKG-----YRFIFLTTAVTNSARLMEAMSEVKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58EN8-1", "uniprot_id": "VP33B_DANRE", "id": "Q58EN8-1", "name": "Vacuolar protein sorting-associated protein 33B", "aln": "MAQTERRDAPELPDFSLLKRLARDQLIFLLEQLPGKKDLFIDADLMSPLDRIANVTILKQHEVDKLYKVELKPIVS--SSDQLCFLIRPR-----------------IQTVK----WISDLVNSDKVAGRFRRYKIIFTPQKFYACETVLEEQGVYGDVTTDEWNFYILPL----DDDILSLELPEFFRDNFLEGDQRWVTTGGGALHLLQSVYGSFSKVYG----------IGRCAKMVYESWRELMEE--GE-----------QRTRQPEFAKVFLIDRDVDFVTPLCSQVVYEGLVDDIFRIKCSSVEFG--------------------PDVTSSDKSIKVMLNSQ-DKVFNEIRNEHFSNVFGFLSQKAKNLQTAYDKRRGMDIQQMKAFVADELKGLKQEHRLLSLHIGASESIMKKKTKQDFQELLKTEHSLLEGFEIRECIAYIEEHINRQVSMIDS-----LRLLCLLSITENGLLSKDYRSLKAQYLQSYGIEHLLTFANLRQLGLLEEQQTGETLTVMESKVGKLVNDKTAG--KLTD-AFSSLAKKSNFRALSKRLALVPKSGEEYDLRVPRDMAYIFSG--AYIPLSCKLIEQVLERDGWTGLEEVTRMLNGQDFAVTG-----GSSSSEARNKSNGQ----------------RIILVMFLGGCTYSEISALRFLGKERG-----CRFIVLTTAITNSGRLLEALLDKHV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBR1-1", "uniprot_id": "Q9VBR1_DROME", "id": "Q9VBR1-1", "name": "", "aln": "------MDLTLDKKLQGFQLVAQEKLCSILCSIPGKKELILEPDLIKPLEHVVTASWLKLKGIQRIYKHDAAQSLPRSADQVHIYMIRSV-----------------LGTFQTLLKQLQPVASEEMPDISMKMYHIVCVPSCYSYFQTLLEQAGLYGLVQLHHFNWDFIYF----DQGVLSLELPNLYECLYLQKNTSPLPAVAQSLRLLQMICGQPSLILS----------FGHHSSQLMQMAKTLGKLP--------------APTNPPDYGGWLVIDRDKDYPASLLTPAIYAGLLLEVFEHSSGEILVDNSKNKIRSQRVELLQGKKSKIGVNSASKPCSIRLNSTSDEIYGDNRYKRFAQVSSLIHAQVKALGLELQKLNDMQLDEMHDYVARKLPKLTELKSKVLRHLNASEIVIQMMG--NFRKLQTLEEDILNNDSRKRLLSEIDELLTTDGQRFNT-----LRLLCLLHHCVG-VAPEELQIFARNYCNLFGHQELGVFQQLSQAGLLP------PLVVEKKAPTKLLSNLPLP--KFQQTEFQANANRLKLLTSSGDGQDGGSSSKSQSSGLQTCPSFVFNG--TYIPLVAQLCSILLKINSAEELSSKLGMIEGLHLHLDS-----GKITPKAYASQVKLNGV---ADQDMFPLRLRNLFVFIVGGASYAEIAACDFVAKLTG-----AQITVASDSLMAGSDLIATAFNR--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20795-1", "uniprot_id": "VPS33_YEAST", "id": "P20795-1", "name": "Vacuolar protein sorting-associated protein 33", "aln": "MNRFWNTKKFSLTNADGLCATLNEISQNDEVLVVQPSVLPVLNSLLTFQDLTQSTPVRKITLLDDQLSDDLPSALGSVPQMDLIFLIDVRTSLRLPPQLLDAAQKHNLSSLHIIYCRWKPSFQNTLEDTEQWQKDGFDLNSKKTHFPNVIESQLKELSNEYTLYPWDLLPFPQIDENVLLTHSLYNMENVNMYYPNLRSLQSATESILVDDMVNSLQSLIFETNSIITNVVSIGNLSKRCSHLLKKRIDEHQTENDLFIKGTLYGERTNCGLEMDLIILERNTDPITPLLTQLTYAGILDDLYEFNSG-----------------------------IKIKEKDMNFNYKEDKIWNDLKFLNFGSIGPQLNKLAKELQTQYDTRHKAESVHEIKEFVDSLGSLQQRQAFLKNHTTLSSDVLKVVETEEYGSFNKILELELEILMGNTLNNDIEDIILELQYQYEVDQKKILRLICLLSLCKNSLREKDYEYLRTFMIDSWGIEKCFQLESLAELGFFTSKTGKTDLHITTSKSTRLQKEYRYISQWFNTVPIEDEHAADKITNENDDFSEATFAYSGVVPLTMRLVQMLYDRSILFHNYSSQQPFILSREPRVSQTEDLIEQLYGDSHAIEESIWVPGTITKKINASIKSNNRRSIDGSNGTFHAAEDIALVVFLGGVTMGEIAIMKHLQKILGKKGINKRFIIIADGLINGTRIMNSIS----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : .: : . * : .*:. : ... * :: . : : .. ::: : ..: . . . . ::*. : : :: : : :*: .* :: . : : : :: : . : . . :*. :. . : . . ::::*: * :.* : * *:: : :. ... * .: :* *:::.: : .*..: : .: * : . : . . .* * : : : * .. ::: :: .: . . *: . *:: : : ***:*** . : :: . : : :* :. : .* . *:: * . :* .: : :. :: . ::. : .: : .. : . : : . :*.::** : .**: .: : * :: . : .: . :: : ", "identical_positions": 39, "similar_positions": 185, "identity": "5.39%" }, { "cls_id": "homologset.agr.RGD:620645", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LM37-1", "uniprot_id": "F1LM37_RAT", "id": "F1LM37-1", "name": "Splicing factor 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDRRVRSTERCDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHTLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNR-------ILRPWQSSETRSITNT-TVCTKCGGAGHIASDCKFQRPGD--P--QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPASNPPPPSLMSTTQSRPPWMNSGPSENRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGTPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMP---PFGMPPAPPPPPPQN-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15637-1", "uniprot_id": "SF01_HUMAN", "id": "Q15637-1", "name": "Splicing factor 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATG--ANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNR-------ILRPWQSSETRSITNT-TVCTKCGGAGHIASDCKFQRPGD--P--QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMP---PFGMPPAPPPPPPQN-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64213-1", "uniprot_id": "SF01_MOUSE", "id": "Q64213-1", "name": "Splicing factor 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATG--ANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHTLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNR-------ILRPWQSSETRSITNT-TVCTKCGGAGHIASDCKFQRPGD--P--QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPASNPPPPSLMSTTQSRPPWMNSGPSENRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGTPQMQGNPTMVPLPPGVQPPLPPGAPPPPPCSIECLLCLLSSPNSLCLSPNRAARIPPRGSDGPSHESEDFPRPLVTLPGRQPQQRPWWTGWFGKAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VEJ1-1", "uniprot_id": "Q9VEJ1_DROME", "id": "Q9VEJ1-1", "name": "Branchpoint-bridging protein", "aln": "MSATPPDLLSLAASREVSAAVAVAASANGGSGRSADKERSRSRDRGRDKDKDRDKDRKKRDKDSRDRDSRRRDDRGDRDRDRERDRDSRSHRSKSRNYDDGDRRRKRSRSRDRDRDRKRDRDRDSRSRRSSSRGGRDDYDRSRRRRSRSRSYERRRNDRGSQRDQRDQHSQRSSRERTHVNPFDTSNSRNSLNQDHDQSRIPSLFDRQQGLETIREEGREQRFDLTQTIQELMGNAGGNKGFASFFNSQNSNDSTSNGAFDNSADSAAERKRKRKSRWGG-SENDKTFIPGMPTILPSTLDPAQQEAYLVQFQIEEISRKLRTGDLGITQNPEERSPSPEPIYSSDGKRLNTREFRYRKRLEEQRHQLIVKMQTVNPEFKPPADYKPPVTRVSDKVLIPQEQHPDINFVGLLIGPRGNTLKAMEKDTGAKIIIRGKGSVKEGKVGRKDGQPLPGEDEPLHAFITAPNPEAVRKAVDKIKDVIRQGIEVPEGHNDLRRMQLRELAQLNGTLRENDIQRCTCGSTDHKSWQCPDKPIITNT-IVCTSCGGTGHLTKDCRNKRPGSGVPGMACEDSQAKIDEEYMSLMAELGEGPPPPSASAKTDPPASNGPQLHR-ASYSIFDKKPSQMQAIQSPP------SSSSRDHQRDLGGWGAAAHEHGMGMEHGMGLDQHGHGLAAMDHGMSLGMEHAMAAYVP------APPGTQAPPP-----------------------MPPPLMPWMSAP------QPPPPATEPLNPPIPGTLPPLIPPPPGTSAPP---------------------MPPWG---GGAYSGWGG--------------GYAPPPPPPCAPPPP-------ALSLSQPPPPPPPSA---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12186-1", "uniprot_id": "BBP_YEAST", "id": "Q12186-1", "name": "Branchpoint-bridging protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFRRINSRYFENRKGSSMEEKKAKVPPNVNLSLWRKNTVESDVHRFNSLPSKISGALTREQIYSYQVMFRIQEITIKLRTNDF-VPPSRKNRSPSPPPVYDAQGKRTNTREQRYRKKLEDERIKLVEIALKTIPYFVPPDDYKRP-TKFQDKYYIPVDQYPDVNFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGSVKEGKNASDLPPGAMNFEDPLHCLIIADSEDKIQKGIKVCQNIVIKAVTSPEGQNDLKRGQLRELAELNGTLREDNRPCPICGLKDHKRYDCPNRKIPNIQGIVCKICGQTGHFSRDCN-----------SSSQRMSRFDRN-----ATVNNSAPIQSNDVHYNSNTHPIQAPKRSRYDNNSTEPPLKFPAS---------------------------------SRYAPSPSPPASHISRQAQNVTPTPPPGLTSSSFSSGVPGIAPPPLQSPPE------------------------------------------SEQPKFSLPPPPGMTTVQSSIAPPPGLSGPP------------------------------GFSNNMGN--------------DINKPTPPGLQGPPGL------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . .: : .:*: :. * * :* * ::*:::: ****.*: :. . ::***** *:*.::*** **** * **:**::* *: * * ** *** * *:..** ** :::*::******:****.**: :::: ..** ***:******* . . . ::***.:: * . : ::*.:. :::: :.: **.:***:: ******.*******:: : ::..: . **. ** :**:: **. . : :::*.: * :.:.. * . .. : * * : : . .* :: . . ** :.** . * * . .***. * .. . . * . * ** ** ", "identical_positions": 123, "similar_positions": 127, "identity": "13.36%" }, { "cls_id": "homologset.agr.RGD:620646", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERC5-1", "uniprot_id": "OTOF_RAT", "id": "Q9ERC5-1", "name": "Otoferlin", "aln": "MALIVHLKTVSELRGRADRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNEVLEIQIFNYSKVFSNKLIGTFRMVLQKVVEENRVEVSDTLIDDNNAIIKTSLSMEVRYQAADGTVGPWDDGDFLGDESLQEEEKDSQETDGLLPGSRPSTRTPGEKSFRSKGKEKTKGGRDGEHKAGRSVFSAMKLGKTRSHKEEPQRQDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTSNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPD------DISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNP-ELTSSTEVQVEQATPVSESCTGRMEEFFLFGAFLEASMIDRKNGD--KPVTFEVTIGNYGNEVDGTSRPQRPRPRKEPG---DEEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQITDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERRLRGVLEELSCGCHRFLSLSDKDQGHSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFS---IVEEELGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQTFQLRAHMYQARSLFAADSTGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGR----------------------TFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPSGKADLPPINGPVDMDRGPIMPVPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHN-YKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAANWNT--------------------TGEVVVSMEPEVPVKKLETLVKLDATSDAVVKVDVAEDEKER-KKKKKKGPSEEAEEEEPDESMLDWWSKYFASIDTMKEQLRQHETSGIDLEEKEEMDSTEGLKGPVKNKE--KSRAAKEEKKKKNQNPGPGQGSEAPEKK--KAKIDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDG-STEEERIVGRFKGSLCVYKVPLPEDVSREAGYDPTYG-------MFQGIPSNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGPHGRVKVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNE----NDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKIVLALLGLLMLALFLYSLPGYMVKKLLGA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESF1-1", "uniprot_id": "OTOF_MOUSE", "id": "Q9ESF1-1", "name": "Otoferlin", "aln": "MALIVHLKTVSELRGKGDRIAKVTFRGQSFYSRVLENCEGVADFDETFRWPVASSIDRNEVLEIQIFNYSKVFSNKLIGTFCMVLQKVVEENRVEVTDTLMDDSNAIIKTSLSMEVRYQATDGTVGPWDDGDFLGDESLQEE-KDSQETDGLLPGSRPSTRISGEKSFR---------------RAGRSVFSAMKLGKTRSHKEEPQRQDEPAVLEMEDLDHLAIQLGDGLDPDSVSLASVTALTSNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPD------DISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNP-ELTSSTEVQVEQATPVSESCTGRMEEFFLFGAFLEASMIDRKNGD--KPITFEVTIGNYGNEVDGMSRPLRPRPRKEPG---DEEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQITDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERRLRGVLEELSCGCHRFLSLSDKDQGRSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFS---IVEEELGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGR----------------------TFAKPLVKMADEAYCPPRFPPQLEYYQIYRGSATAGDLLAAFELLQIGPSGKADLPPINGPVDMDRGPIMPVPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHN-YKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPNWNTTVRLLRGCHRLRNGGPSSRPTGEVVVSMEPEEPVKKLETMVKLDATSDAVVKVDVAEDEKER-KKKKKKGPSEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQHETSGTDLEEKEEMESAEGLKGPMKSKE--KSRAAKEEKKKKNQSPGPGQGSEAPEKK--KAKIDELKVYPKELES--EFDSFEDWLHTFNLLRGKTGDDEDG-STEEERIVGRFKGSLCVYKVPLPEDVSREAGYDPTYG-------MFQGIPSNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGPHGRVRVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNE----NDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKFLLLFLLLLLFALFLYSLPGYLAKKILGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC10-1", "uniprot_id": "OTOF_HUMAN", "id": "Q9HC10-1", "name": "Otoferlin", "aln": "MALLIHLKTVSELRGRGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNEMLEIQVFNYSKVFSNKLIGTFRMVLQKVVEESHVEVTDTLIDDNNAIIKTSLCVEVRYQATDGTVGSWDDGDFLGDESLQEEEKDSQETDGLLPGSRPSSRPPGEKSFR---------------RAGRSVFSAMKLGKNRSHKEEPQRPDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTTNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPD------DISSGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSNP-ELTSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDRRNGD--KPITFEVTIGNYGNEVDGLSRPQRPRPRKEPG---DEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYPERRLRGVLEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFS---IVEEETGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGR----------------------TFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPAGKADLPPINGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHN-YKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKE--KKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKGSMKGKE--KARAAKEEKKKKTQSSGSGQGSEAPEKK--KPKIDELKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDG-STEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYG-------MFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIEDENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNE----NDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKILGA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SPC5-1", "uniprot_id": "OTOF_DANRE", "id": "Q5SPC5-1", "name": "Otoferlin", "aln": "MALVVHLKTVTELRGKGDRIAKVTFRGLSFFSRVLENCEDEARFEQAFRWPIGSQVDGDEMLEIQVFNYSKVFTNRLIGTFRMVLQKVVEEGHLEVSDTLIDDNNTAIQTTISIEIKYQTMDGSVKVWSDGEFL-DIPDDLDGTFQFETDSLLSGRSQSSGTSPGRSIHG---------IPTFRKAGKGVFSAMKLGKTRTSKDDHKKGDDAAILDAEDLDRKAMRLGGILDPDTISLASVTAVTTNVSNKRSKPDIKMEPSSGRPVDYQISVTVIEARQLVGLNMDPVVCVEIGEEKKYTSMKESTNCPYYNEYFVFDFHVPPDVMFDKIIKISVIHSKNLLRSGTLVGTFKLDVGTVYTQPEHQFHHKWAMLSDPD------DITTGCKGYVKCDIAVVGKGDNIKTPHKASEADEDDIEGNLLLPEGVPSERQWARFYVKIYRAEGLPKMNTSIMANVKKAFIGENRDLVDPYVLVQFAGQKGKTSVQKSSYEPIWNEQVIFTEMFPPLCRRLKVQIRDSDKVNDVAIGTHFIDLRKVSNDGDKGFLPTMGPAWVNMYGSTRNYTLMDEHQDLNEGLGEGVSFRARLLISIAVEILDTTSA-EIMSSTEVHMEPVSNISESATGKMEEFFLFGSFLEATMIDRKIGD--KPISFEVTIGNYGNQIDGVSKPALAKKKKEGGGESEEEESELIHNSSEEEAEDDGDLTSVPSTPPMKPVITDRNYFHLPYFEKKPCIYIKSWWQDQRRRLYNSNIMDKIADKLEEGLNDVQEIIKTEKAYPERRLRGVLEELSTSCSRFVTLANKDQNLSGRTKLDRERLKSCMREMESMGQQAKTIRTQVKRNTVRDKLKLVLNFLQRLRFLADEPQHSIPDVFIWMISNNKRIAYARIPSKDILYS---IVDEEMGKDCGKVKAVFLRLPGKKGFGPAGWTVQAKLEMYLWLGLNKQRKDFLIGLPSGFEENKAVKGIGIQAVPPISLVYNMKQVFQLRAHMYQARSLFAADTSGLSDPFARVFFSTHSQVTEVLSETLCPTWDQLLVFDNVELYGEAGELRDDPPIIVIELYDQDTVGKAEFIGR----------------------TFAKPLTKMVDEHYGPPRFPPQLEYYQIYRGNCAAGDLLAAFELLQIGPAGRAALPPIDGPTDSDRGPILPVPLGIRPVLSRYRIEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSALIQN-YKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYILVGSHAVTTLRKFIYSPPDKTANNWAH--------------------TGDIVVNMSPEPNIKKMDTVVKIEATTDAVVKVDLNEDEKEKEKKKKKKKKGEEVEEEEPDESMLDWWSKYFASIETMMENLRAQEAAQAEAEEREDLEIAAESAEIKADDFPMKGTKPKEKSKDKKSTKDKKKNNDGTEKRPPKPKVDELMVYNKELES--EFGSFEDWLHTFNLYRGKAGDDDDHNVVDEDRIVGRFKGSLCMYKLPLSEEITREAGFDPNMG-------MFQSIPHNDPINVLVRIYIIRATDLHPADINGKADPYIVIKLGKSDIRDKENYISKQLNPVFGKSFDIEATFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRYYSKHRATCGIASNYSVHGYNVWRDPQKPAQILAKLCKEGKLDGPHYGPGGRVKVANRIFLGPTEIEDESGLKKQTEEHLALTVLRHWEEIPRVGCKLIPEHVETRPLLNPDKPGIEQGRIEMWVDMFPMDVPAPGPAIDISPRKPKRYELRVIIWNTDEVILEDDDYFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFVFPFDYLMAEEKIVISKKESMFSWDETEYKIPARLTLQVWDADHFSADDFLGAIELDLNKFPRGAKTAKQCSLDMVLKEHELPTISIFKQKRVKGWWPFVAQNE----NDEFELTGKVEAELHLLTAEEAEKSPVGLGRNDPEPLEKPNRPDTSLMWFMNPLRSIRYFIWHNYRWLILKALALLLLLLLVGLFLYSIPGYLVKKLLGA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z0E5-1", "uniprot_id": "B7Z0E5_DROME", "id": "B7Z0E5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYMDDCFAGAPQEFLICITVHKAAQVGVTTGELYVRISLDKMTKSTKSFPNTENPFFNEYFVFEFHCTLTELLRLTILFELKKHMTYKKN-VVVGELLVDLHSVWNQSNHGYFKKWGRLEAPIGENQTLENAVAPHGYLQLDLAIVSQHSPVSYALGSEEQDTQNLN-KWTVDHDFDDIEKNLLTNVNIFAPSNIR----YFVAFYRGYFIKQS----NYMIQVSFAGFNGKTPVVKNTTTPVWNYEINFAWMYPSVAQRFLILIFAHEHLQWKCVAEFELCLEEIAFNG----TPSLGPTYLHLYDPVN-----------------PMIYVGRLLMELRSEMLTDSQPTHTLSSKTVPGLDETRFWHDDVYLIEFLPLMGHHILTSGTAYKISARLAEHTSNVLEGQLRTPLDRFKSAMNSKNFRREAP---FQSCMFRVRLPDNRAKYESDFFMLDIVNYMRSELDTFKLFQRKYP-----------LQDDEQAKCLKVIVNNILTRIKEGLDAHRFDHDVQPQRTTWDINRQLYLLDYFAKLPLELQN-----------LKQKLRSCFLEHLDT-----------SIGDVVNELQRLVAEIGSLSSMAR-TQDEWPELVLSLSASGKDVGVCRLNAKLFLNLRNQDADQDQETLCWRLKSFSFKSAGCSHTCPNCGCTTAIVSGCLSIVVERERKRFLAVVNKEWAN----------IEPMLWQLNPEQTHFLCHVYIHQAKVRPGGEKKNICDSHLRVLFADQACETYTSPGTLSPIWNAVITFNWVSLPGGIGLYLKNPPLLSLEFYNSERSLPEDLVGMGSVAMSVISEDRASDSNWEDAGVFGCSKNPLRKLQRLKYLTPPPLKWVPIARKGTLQAEVLMSAEIIQISMESLTTGQNDKKEPQLATG----IPMAIRPTMQNFVLEVFFVGLRNYSKSSMSSAGKRKINLMMGDLVLSSGPSTARIRNSINFLVAYASGVVSLPDQQDYWPAIIATDVLLSGFSSESILGAALIPNSSNFLQR-----------------------------------------DRTLKCVFKKEQEAAEASTTVSVDEDDEDEEE--------ELEWEEEETKPSRISSWWMRLLFAFG-LRPAPYANRHALRFHDDLDDHELVEEREFTWWTKFYNSMYWSAAEMCHEHKHR--------------------LVIYYEELEKQAQFGYLQDWAVPVQLVHGVKFKKHGP-PKEDIYATLKLQLKLTPCQCPVLEDPGGGGDMVRNMSNPIHPRHQSTLQSLGETVKLLVRVYVVQGVQMRPRDVKGDSDCYVKLFLGGKTFSDRAHFSPNHSNPVFGRLFEMEATLPGDHMLQVMVYDHDKI-KDEVIGQTNIDLEDRWRTRHRATVGLANEYTKSGYNHWHDVKLPSEILIDLCQKRGIQAPYYYG-NVIEVDGMLFGDETLISKD----EELQERLSLAVLKNMDKLPSFGYKLVPEHVETRSLCRDDFPNVEQGKLQLWIELFEANIYVP-SPIDITPVPPADFEVRVVVKNLVGIQAGDKNIFG-KLMSDVYVIGWCE-DEDKRQSTDIHYRSFAGDAAFNWRMVFGLKYSPNEDLMVIRRKAGLL--EEIEFKKPPIIYLQVWDKDVLTKDEYLAALELNLSNMYAPYPAAQLCKPYPKK----RKRINLFKRKVINGWFPLQSNAHPSQRSQAAVQNGKMQLSIEVCTDVEAVNRPAGRGQDPPMALEPPYRPDSSFNPLTHPCKSFQHILWPVIRKYVLWTLLILIVILGLVLFFSNLPAKLMTIPLE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* * :: :.:** :* *: . : * :.:.. .* *. .*: *::******:** . :: * :.: : . :. .:** : :*: :*:.*.:* :.:**. *. * : : . :**:: *:*:*.: . :. . :.* * :::: : : ... .: *:*: ...: ::* : ** :. : : * *** :***.* *.: *:** :: *: ::*.:.:*: : * :::: .:. . : *.::: :* *::**:::::*.... : : .**:: : *:: :.. . **. * : . .. . :* : *:* .: :: : . : :* *: . :* . . .: :. . :. : . .::.. .*: : . *:. : : *: * *:.: *:::* :::***: : ..: . :. * *. . : * : :::*:**: * . . * ::*: : * :* .*.. *::.: : :..* :. .*: :* :* .::: . * ::*:. :: .* . . * :. * : :.::** ** : : : * : : : * :.:::**: ..:...:.*.. **:* :: * . **.* *: ::.*: :.* * .:**:: :*:*:.: :::* .*. . : . ** *:: * * . .::* : *::**. . : . : * :*:.***.:..: :**:* ***: .: .::...: :::: .. :.*. ::. ** . *.**::: *.: * .*. ::*: :.. .*: : :* : . : * :.:.*.** ::::* * *** . : .** : : :: : :. : :: :: : . . . . : .: . * :* :***. :*. ::** ..:* :* .... :: . ::: .* : *: *: .. . . . .:.:::***:*:::..:::* *::*.:* *: : ** . : *: :: .:: *****: *::**::* : ** * *** * : .*::**:*:****:*: ::**** *:*. *: *** *:* *::** **:. ::.*:: . :.* . :* . : *..: : :*:::* .*:: :.:* * :*:*******.* . * *.:***::::*:::* :: .* ..:**:* * :*:**:: * : *.: * : **::* ** : :::.:*.**:**:*::*:. **** :* :.* *: :*: :* .:: :* *:* *. : **:** * :: *::*.*:**:*..: :*: *. :.:**:* ::**:*: :. . .: .**:: .:.: * ** : *.* .:: * .** * ***::: : :* :* :::: : :: : :: :* . **: .:*. : . * ", "identical_positions": 345, "similar_positions": 640, "identity": "16.67%" }, { "cls_id": "homologset.agr.RGD:620647", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A7L9Z8-1", "uniprot_id": "AT2C2_MOUSE", "id": "A7L9Z8-1", "name": "Calcium-transporting ATPase type 2C member 2", "aln": "----------------MGRRLKFLQKLAFLGQNHRYKALERDEVETLIDEQCELKAIEREKTVAA----------------------------------------LPPGEACKCSREELARAFHVDLDSGLS-EFAVAQRRLVHGWNEFVTDNAEPVWKKYLDQFRNP-LILLLLGSSVVSVLTKEYEDAVSIALAVLIVVTVGFIQEYRSEKSLEELTKLVPPECNCLRDGKLRHMLARDLVPGDIVSLSMGDRIPADIRLTEVTDLLVDESSFTGEVEPCGKTDSPLADGG---------DLSTLSNVVFMGTLVQCGKGQGVVIGTGEQSQFGEVFKMMRAEETPKTPLQKSMDKLGKQLTIFSFGIIGLLMLVGWVQGKPFLSMFTVGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTATQLVTSDGFHAEVSGVGYSGEGTVCLLPSKEVIKGFDNVSVGKLVEAGCVANNAVIRKN--AVMGQPTEGALVVLAMKMNLGSIKDSYVRKKEIPFSSEQKWMAVRCGPK-SEDGEDIYFMKGAFEEVIHHCSMYNN--GGIPLPLTPQQKSYCQQEEKKMGSLGLRVLALASGPE-----------LGRLTFLGLVGIIDPPRAGVKEAVQVLSESGVSVKMVTGDALETALAIGRT----------------------------------------------------------IGLCNEKLKAMSGEEVEGTEQGALAARVRQVSVFFRTSPKHKVKIIKALQESGAIVAMTGDGVNDSVALKSADIGIAMGQTGTDVSKEAANMILVDDDFSAIMSAVEEGKGIFYNIKNFVRFQLSTSIAALSLITLSTVCNLPSPLNAMQILWVNIIMDGPPAQSLGVEPVDRDALRRPPRSVGDTILNRALILRVLMSAAVIIGGTLFIFWREIPA-NGTSTPRTTTMAFTCFVFFDLFNALSCRSQTKLIFEIGFFRNRMFLYSVLGSLLGQLAVIYAPPLQKVFQTENLSALDLLLLTGLASSVFILSELLKLWEKFLSRARPTQMLPEAV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R4C1-1", "uniprot_id": "AT2C2_RAT", "id": "Q8R4C1-1", "name": "Calcium-transporting ATPase type 2C member 2", "aln": "----------------MGRRFKFLQKLAFLGQNHRYKALERDEVDTLIDEQYELKAIEREKAVAA----------------------------------------LPPREACKCSKEELARTFHVDLDSGLS-EFAVAQRRLVHGWNEFVTDNTEPVWKKYLDQFRNP-LILLLLGSSVVSVLTKEYEDAISIALAVLIVVTVGFIQEYRSEKSLEELTKLVPPECNCLRDGKLRHMLARDLVPGDVVSLSMGDRIPADIRLTEVTDLLVDESSFTGEVEPCSKTDSPLAGGG---------DLSTLSNVVFMGTLVQCGKGQGVVIGTGEQSQFGEVFKMMRAEETPKTPLQKSMDKLGKQLTVFSFGIIGLLMLVGWVQGKPLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTATQLVTSDGFHAEVSGIGYSGEGTVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVVRKN--AVMGQPTEGALVVLAMKMNLGSIKDSYIRKKEIPFSSEQKWMAVRCSLK-NEDEEDVYFMKGAFEEVIHHCSTYNN--GGIPLPLTPQQKSYCQQEEKKMGSLGLRVLALASGPE-----------LGRLTFLGLVGIIDPPRAGVKEAVQALSESDVSVKMVTGDALETALAIGRT----------------------------------------------------------IGLCDEKLKAMSGEEVEGMEQDALAARVRQVSVFFRTSPKHKVKIIKALQESGAIVAMTGDGVNDSVALKSADIGIAMGQTGTDVSKEAADMILVDDDFSAIMSAVEEGKGIFYNIKNFVRFQLSTSIAALSLITLSTVCNLPNPLNAMQILWVNIIMDGPPAQSLGVEPVDRDALKRPPRSVKDTILNRALILKILMSAAVILGGTLFIFWREIPE-NRTSTPRTTTMAFTCFVFFDLFNALSCRSQTKLIFEIGFFRNRMFLYSILGSLLGQLAVIYAPPLQKVFQTENLSALDLLLLTGLASSVFILSELLKLCEKFCSRAKADQMLPEAV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75185-1", "uniprot_id": "AT2C2_HUMAN", "id": "O75185-1", "name": "Calcium-transporting ATPase type 2C member 2", "aln": "--------------MVEGRVSEFLKKLGFSGGGRQYQALEKDEEEALIDEQSELKAIEKEKKVTA----------------------------------------LPPKEACKCQKEDLARAFCVDLHTGLS-EFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNP-LILLLLGSALVSVLTKEYEDAVSIATAVLVVVTVAFIQEYRSEKSLEELTKLVPPECNCLREGKLQHLLARELVPGDVVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGG---------DLTTLSNIVFMGTLVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPKTPLQKSMDRLGKQLTLFSFGIIGLIMLIGWSQGKQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLRAEVSGVGYDGQGTVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKN--AVMGQPTEGALMALAMKMDLSDIKNSYIRKKEIPFSSEQKWMAVKCSLK-TEDQEDIYFMKGALEEVIRYCTMYNN--GGIPLPLTPQQRSFCLQEEKRMGSLGLRVLALASGPE-----------LGRLTFLGLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIGRN----------------------------------------------------------IGLCNGKLQAMSGEEVDSVEKGELADRVGKVSVFFRTSPKHKLKIIKALQESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLNAMQILWINIIMDGPPAQSLGVEPVDKDAFRQPPRSVRDTILSRALILKILMSAAIIISGTLFIFWKEMPE-DRASTPRTTTMTFTCFVFFDLFNALTCRSQTKLIFEIGFLRNHMFLYSVLGSILGQLAVIYIPPLQRVFQTENLGALDLLFLTGLASSVFILSELLKLCEKYCCSPKRVQMHPEDV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PG15-1", "uniprot_id": "M9PG15_DROME", "id": "M9PG15-1", "name": "P-type Ca(2+) transporter", "aln": "MSKTPKPLTSKRRTSPASPGSTVLIESPTTSSGVRNRRSKIKGVDSKPNPQRTISHVKDSRAVPQNVKPGKVADMKDCKEPDEDNVDQQNGNIIQTGLTLTPEMLLSTSESSTHSASEVAGRLQVDVRTGLK-WTEAKYRAKIIGHNELLLVAEDPTWKKYIEQFRNP-LILLLLGSALVSVIMKQFDDAVSITIAILIVVTVAFIQEYRSEKSLEELKKLVPPECHCLREGRLDTFLARELVPGDIVHLNVGDRVPADVRLFEAVDLSIDESSFTGETEPARKITDVLLNNTN------VKDHSNMKNIAFMGTLVRCGNGKGIVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMDILGAQLSFYSFLIIGVIMLLGWLQGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNSIVKKLPTVETLGCVNVICSDKTGTLTKNEMTATIIITSDGYMADVTGAGYNDQGEIHIRHCNNVEMAKTNITN--LLEIGAVCNNAYIQNG--TLLGQPTEGALVAVAMKNGMYATAENYVRIQEYPFSSEQKMMAVKCIHKYNNNKEEIFFAKGALETLLPQCTKYQF--GTQTVPLTKQNEAEFLAEAYEIGRKGLRVLALAKGRS-----------MQDLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAIDPSRRLQAVPTHAIPAWPTAGGVPLCSASACCSTNCLENAMKEIYLTALAQQGLPLVTANLIGIDTIHHQTLSGQEMDQMNEHQLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIALATLMDIANPLNAMQILWINIIMDGPPAQSLGVEPVDHDVLKQKPRNVKQPMITKSVVVNVLLSASIIVLGTLWVFQREMADGTLGKTKRDTTMTFTCFVFFDMFNALSCRSQTKSVFTIGLTTNRMFLLAVAFSIIGQMLVVYFPPLQMVFQTEALTPYDIFFLVSLTSSVLVVSEIKKWFERTMERKMYSTRSELDFV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13586-1", "uniprot_id": "ATC1_YEAST", "id": "P13586-1", "name": "Calcium-transporting ATPase 1", "aln": "------------------------------MSDNPFNASLLDEDSNR--EREILDATAEALSKPS-----------------------------------------PSLEYCTLSVDEALEKLDTDKNGGLRSSNEANNRRSLYGPNEITVEDDESLFKKFLSNFIEDRMILLLIGSAVVSLFMGNIDDAVSITLAIFIVVTVGFVQEYRSEKSLEALNKLVPAECHLMRCGQESHVLASTLVPGDLVHFRIGDRIPADIRIIEAIDLSIDESNLTGENEPVHKTSQTIEKSSFNDQPNSIVPISERSCIAYMGTLVKEGHGKGIVVGTGTNTSFGAVFEMMNNIEKPKTPLQLTMDKLGKDLSLVSFIVIGMICLVGIIQGRSWLEMFQISVSLAVAAIPEGLPIIVTVTLALGVLRMAKRKAIVRRLPSVETLGSVNVICSDKTGTLTSNHMTVSKLWCLDSMSNKLNVLSLDKNK--KTKNSNGNLKNYLTEDVRETLTIGNLCNNASFSQEHAIFLGNPTDVALLEQLANFEMPDIRNTVQKVQELPFNSKRKLMATKILNP--VDNKCTVYVKGAFERILEYSTSYLKSKGKKTEKLTEAQKATINECANSMASEGLRVFGFAKLTLSDSSTPLTEDLIKDLTFTGLIGMNDPPRPNVKFAIEQLLQGGVHIIMITGDSENTAVNIAKQIG--------------------------------------------------------IPVIDPKLSVLSGDKLDEMSDDQLANVIDHVNIFARATPEHKLNIVRALRKRGDVVAMTGDGVNDAPALKLSDIGVSMGRIGTDVAKEASDMVLTDDDFSTILTAIEEGKGIFNNIQNFLTFQLSTSVAALSLVALSTAFKLPNPLNAMQILWINILMDGPPAQSLGVEPVDHEVMKKPPRKRTDKILTHDVMKRLLTTAACIIVGTVYIFVKEMAE-DGKVTARDTTMTFTCFVFFDMFNALACRHNTKSIFEIGFFTNKMFNYAVGLSLLGQMCAIYIPFFQSIFKTEKLGISDILLLLLISSSVFIVDELRKLWTRKKNEEDSTYFSNV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : :. . .. * .. . .: : .* ** . * * **: :. :**::.:* : :****:**::**:: : :**:**: *:::****.*:********** *.****.**: :* *: .** *****:* : :***:***:*: *. ** :***.:*** ** * . : . : . :.:*****: *.*:*:*:.** :.** **:**. * ****** :** ** :*:. ** :**:: *:* **: .** :.**************:* ***.***:****:. **::** *****. .*:********* *.**.: : *. .:. . . : .: . : * :.*** . : .:*:**: **: : : :. : :* **.*::* **.: : : : ***:* :: .: * * . ** :.: :. ****:.:*. : * : **:*: **** *: ::: * :..* : *:***: :**: * * : : ..:**:::: .. * :*.:* *.:*.**::*:::*:. * :*.********. *** :***::**: ****.***::*:*.:*** :*: *:******* **:**: ******::**:*::*:* .:..*********:**:***************::.::: **. : ::.: :: .:* :*: *: **:::* :*:. * * ***:********:****:** :** :* **: *:** :: *::**: .:* * :* :*:** * *:::* ::***:::.*: * : ", "identical_positions": 354, "similar_positions": 274, "identity": "32.57%" }, { "cls_id": "homologset.agr.RGD:620648", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63156-1", "uniprot_id": "BARH1_RAT", "id": "P63156-1", "name": "BarH-like 1 homeobox protein", "aln": "-------------------------------------------------------------------MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSD----------------------------------------------CSSPASPGRDCLETSTS-----------------------------------------------------------------------------------------RPGAASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAGEDFRDKLDKSVSSASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSP------YFYPQSLVSN----LDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASE---------------PPPPLPPLPGVLPRAAQPR--------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63157-1", "uniprot_id": "BARH1_MOUSE", "id": "P63157-1", "name": "BarH-like 1 homeobox protein", "aln": "-------------------------------------------------------------------MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSD----------------------------------------------CSSPASPGRDCLETSTS-----------------------------------------------------------------------------------------RPGAASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAGEDFRDKLDKSVSSASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSP------YFYPQSLVSN----LDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASE---------------PPPPLPPLPGVLPRAAQPR--------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZE3-1", "uniprot_id": "BARH1_HUMAN", "id": "Q9BZE3-1", "name": "BarH-like 1 homeobox protein", "aln": "-------------------------------------------------------------------MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSD----------------------------------------------CSSPASPGRDCLETGTP-----------------------------------------------------------------------------------------RPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAAEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSP------YFYPQSLVSN----LDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASE---------------PPPPLPPLAGVLPRAAQPR--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24256-1", "uniprot_id": "BARH2_DROME", "id": "Q24256-1", "name": "Homeobox protein B-H2", "aln": "MTTMPPEMSATTAAPVGSAPSATAHHPAAVGGGMPRPASPAVGSNTTTATATTATRSRFMITDILAGAAAASAAAAAAAAALAAASSGGGRGSPTDSEREQSLVAQHHHHHQQQQQHHHHQQQQQQQQHQQAALQQYIVQQQQLLRFEREREREREREHYRERHSPPGNNPYAHHPMPPHLLAHFPPAHYAVLQQQQQQQQQQQHPHPHHLQLERERLEALHRHGHGLTGDPAQHLSHLSHLSHQQHHPHLHHPMHDERSRSPLMLQQLGGNGGNNNNNNNNSSSASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQASTIDDSDSDDCGGKDDDGDDSMKNGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAAAQSPHGATP-SAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPGMSLPGMPAPP----PPGAAPMLSGYY--AAAAAAAASAGAQQQQQQPPAASRSPATSQSANSEADCERTSSSSRQRLITPSPPLNPGSPPHRERINEEEDRERDEERDIERERERERERDEDDEEELALEV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24255-1", "uniprot_id": "BARH1_DROME", "id": "Q24255-1", "name": "Homeobox protein B-H1", "aln": "---MKDSMSILTQTPS-----------------EPNAAHPQLHHHLS--TLQQQHHQHHLHYGLQPPAVAHSIHSTTTMSSGGSTTTASGIGKPNRSRFMINDILAGSAAAAFYKQQQHHQQLHHHNNNNNSGSSG-----------------GSSPAHSNNNNNINGDNCEASNVAGVGVLP-------SALHHPQPHPPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAM-----QQHY------------------AAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGN----MDDHSVCSNGGKDDDGN-SVKSGSTS--DMSG-----LSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGS-PYLGAWPYAAAAGAA--HGATPHTNIDIYYRQAAAAAAMQKP-LPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAAAASAANPGGPHPVAPPPSVGGGSPPSGLVKPIPAHSASASPPPRPPSTPSPTLNPGSPPGRS---------------------VDSCSQSDDEDQIQV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : : :.. *.* . . * : .. . :. . :: :. .: .. . .... . :.. : * . .. ..*.: .:*. . . * ** ************ **:***********:* *** .*:*:* *****************************::*:**:: .. : *. : : * : : :* :*...*:*:* :* . .. . . *.. ** . ", "identical_positions": 84, "similar_positions": 83, "identity": "12.88%" }, { "cls_id": "homologset.agr.RGD:620649", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09602-1", "uniprot_id": "HMGN2_MOUSE", "id": "P09602-1", "name": "Non-histone chromosomal protein HMG-17", "aln": "MPKRKAEGDAKGDKTKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKAEGAGDAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AC51-1", "uniprot_id": "A0A8I6AC51_RAT", "id": "A0A8I6AC51-1", "name": "Non-histone chromosomal protein HMG-17", "aln": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05204-1", "uniprot_id": "HMGN2_HUMAN", "id": "P05204-1", "name": "Non-histone chromosomal protein HMG-17", "aln": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKEGNNPAENGDAKTDQAQKAEGAGDAK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************:*************************************************:.*****************:******", "identical_positions": 86, "similar_positions": 4, "identity": "95.56%" }, { "cls_id": "homologset.agr.RGD:62065", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K6F4-1", "uniprot_id": "A0A0G2K6F4_RAT", "id": "A0A0G2K6F4-1", "name": "Exostosin-like 3", "aln": "-MTGYTMLRNG--------GVGNGGQTCMLR---------------WSNRIRLTWLSFTLFIILVFFPLIAHYYLTTLDEADEAGKRIFGPRAGN--ELCEVKH------VLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPK--VTRGCRLHNCFDYSRCPLTSGFPVFVYDSDQFAF---GSYLDPLVKQAFQATVRANVYVTENAAIACLYVVLVGE-IQEPAVLQ-----------------------PADLEKQLHSLPHWRTDGHNHVIINLSRK---SDTQNLLYNVSTGRAMVAQSTFYAAQYRAGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPSLLISSGCATRLFEALEVGAVPVVLG-EQVQLPYHDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEVAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTVTDCYRSWNSAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVQREQFTVVMLTYEREEVLMNSLERLNGLPYLNK-------------------------VVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDI--PHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WVL6-1", "uniprot_id": "EXTL3_MOUSE", "id": "Q9WVL6-1", "name": "Exostosin-like 3", "aln": "-MTGYTMLRNG--------GVGNGGQTCMLR---------------WSNRIRLTWLSFTLFIILVFFPLIAHYYLTTLDEADEAGKRIFGPRAGS--ELCEVKH------VLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPK--VTRGCRLHNCFDYSRCPLTSGFPVYVYDSDQFAF---GSYLDPLVKQAFQATVRANVYVTENAAIACLYVVLVGE-MQEPTVLR-----------------------PADLEKQLFSLPHWRTDGHNHVIINLSRK---SDTQNLLYNVSTGR-HVAQSTFYAAQYRAGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPHLLISSGCATRLFEALEVGAVPVVLG-EQVQLPYHDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEVAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTVTDCYRGWNSAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVQREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDI--PHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43909-1", "uniprot_id": "EXTL3_HUMAN", "id": "O43909-1", "name": "Exostosin-like 3", "aln": "-MTGYTMLRNG--------GAGNGGQTCMLR---------------WSNRIRLTWLSFTLFVILVFFPLIAHYYLTTLDEADEAGKRIFGPRVGN--ELCEVKH------VLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPK--ATRGCRLHNCFDYSRCPLTSGFPVYVYDSDQFVF---GSYLDPLVKQAFQATARANVYVTENADIACLYVILVGE-MQEPVVLR-----------------------PAELEKQLYSLPHWRTDGHNHVIINLSRK---SDTQNLLYNVSTGRAMVAQSTFYTVQYRPGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPRLVISSGCATRLFEALEVGAVPVVLG-EQVQLPYQDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEAAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPRYLRNFTLTVTDFYRSWNCAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDI--PHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XZ08-1", "uniprot_id": "EXT3_DROME", "id": "Q9XZ08-1", "name": "Exostosin-3", "aln": "MPPAYDLGHSGEAYQPLDTGSGGGNEACAPNSSSAQIRHSMGFRTSWMRQFRRYKLPMVLLMLLFLVSCLAYRILSVEQDAPPLDLHRSSPLLDAYEDFSAMRAGDLKMRIEEMVRIKSTVSVELRELESRRQKLQSDISQYNQKIEELKQELLREQTELERLKISVEQAQVAQREAVQRNTPDLALPRSLLPNTLPRKSNPITGGMAASCEMHNCFNHSRCSLTSGFPVYLYDPDEHSVQRKGYDIDGFLKTTLKQTLGYNAHIVKDPKHACIYLVLVGEALLEQDLLRNNRYAAQEAEHQQPSTPTLENDCPVDMEK-LYSLPYWGGDGRNHVLLNLARRDLTSHRTNPLYRQNTMRAIVVQSAFEREQFRPGYDLIVPPILGPPGGDVWQECAEMVPARRKYLLTYQG-ELRPKQSSLNPLDAFILEHLAD----------MAKGATQDQFVLQFQCVPATEQQEGDSLP-DWTLCGSDSSRRQLLKDSTFSLILPPLN-GRVSSTLMLARIYEALRSGAVPVILGADELRLPYAETVDWRRTALLLPKARITELHFLLRAVQDADLLLLRRQGRLIWERYLSSVQATVDTVIASLRDRLGIPPRPVPSVIAQSVFNSTFIPLKSDPPVGLDTEPEESLGPIEPPYPSPAFRRNYTILRMQAKEAWNDWLDPFYLYPQLPFDPALPSEAKFMGSHTGFRPIGKGLGGAGKEFGESLGGNYPREQFTIVMLTYEREQVLMDSLGRLYGLPYLHKVVVVWNSPKPPLDDLRWPDIGVPVAVLRAPRNSLNNRFLPFDVIETEAVLSVDDDAHLRHDEILFGFRVWREHRDRVVGFPGRYHAWDLGNPNGQWHYNSNYSCELSMVLTGAAFVHKYYLYLYTYHLPQAIRDKVDEYMNCEDIAMNFLVSHITRKPPVKVTSRWTFRCPGCPVSLSEDDTHFQERHKCINFFSRVFGYTPLLNTQYRADSILFKTRIPHDKQKCFKYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* : :.* * *.*.::* . * .::* *.:.*:::*.:.. :*: *:. ::* . : .* . ::. :: : :: **:.:** ** :**::**:*:*:*:: * *** *:.: . : :* :** :.*:: : :* : :* *.*:** ***:. * . : .*.:****::***.*******::**.*:. . * :* ::* ::: * *.::.::. **:*::**** : * :*: *.::** *.***:* **:***::**:*: *. * **. .* * *.**:* *:*.*:**:*.*:: . . : * . **.:****:*:** ::.. :***: :* * .* : *.**. : *. : ::* *** :*:***. ..* :*** ***:**:.* : : *: :*::***. *****:** ::::*** : ::*..:**::**.*:**:*****::.*:*** :*****::** *:*:.:: .:**:* :* *: **. *: . * .: : : . :** :. : : : . ****.** : **:*: : ..** .**:*:*: ****.*******:** ******* * **:**** :**** *****:********:***:** ** *****:* *:*: :*********:: *****:**:***********:******** ***:***********: *: .* ******************.**** ***:* :****** ****:*******************:************** :**.**:**:********* :*:** *** **:*.**:*****:**** ****:*", "identical_positions": 436, "similar_positions": 261, "identity": "44.22%" }, { "cls_id": "homologset.agr.RGD:620650", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62739-1", "uniprot_id": "RAB3I_RAT", "id": "Q62739-1", "name": "Rab-3A-interacting protein", "aln": "------------------------------------------------------------------------------------------------------------------MANDPLEGFHEVNLASPTSPDLLGVCDPGTQEQTTSPSVIYRPHPSTLCSATIQANALNLSDLPTQPVYSSPRHLNCAEISN-ISIHVPEPASSVASEVAAGLTRFTSRKDSCNAEREFLQGATVTEASAG----------------------------NDDIFGLSTDSLSRLRSPS-VLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVREANVKQATAEKQLK-----------------EAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLAAGKTPFKRGHTRNK-----------------------------STSSAMSGSHQD------------------------------FSAIQPIVKDCREADLS-----LYNEFRSWKDEPTMDRTCPFLDKIYQEDIFPCLT---------FAKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPK--------------KCALTGQSKPCKHRIKLGDSSSYYYISPVCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68EF0-1", "uniprot_id": "RAB3I_MOUSE", "id": "Q68EF0-1", "name": "Rab-3A-interacting protein", "aln": "------------------------------------------------------------------------------------------------------------------MANDPLEGFHEVNLASPTSPDLLGVCDPGTQEQTTSPSVIYRPHPSTLCAAPLQANALDLSDLPTQPVYSSPRHFNCAEVSN-ISAHAPDPASSVPSAVASGLTKLTSRKDSCNAEREFLQGATITEASAG----------------------------NDDIFGLSTDSLSRLRSPS-VLEVREKGYERLKEELAKAQR--------------------------------EAHKMVREANVKQATAEKQLK-----------------EAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLAAAKTPFKRGHTRNK-----------------------------STSSAMGGSHQD------------------------------LSVIQPIVKDCKEADLS-----LYNEFRSWKDEPTMDRTCPFLDKIYQEDIFPCLT---------FAKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPK--------------KCALTGQSKPCRHRIRLGDSSCCYYISPFCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QF0-1", "uniprot_id": "RAB3I_HUMAN", "id": "Q96QF0-1", "name": "Rab-3A-interacting protein", "aln": "--------------------------------------------------------------------------------------------------MGLKKMKGLSYDEAFAMANDPLEGFHEVNLASPTSPDLLGVYESGTQEQTTSPSVIYRPHPSALSSVPIQANALDVSELPTQPVYSSPRRLNCAEISS-ISFHVTDPAPCSTSGVTAGLTKLTTRKDNYNAEREFLQGATITEACDG----------------------------SDDIFGLSTDSLSRLRSPS-VLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVREANIKQATAEKQLK-----------------EAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLPGGKTPFKKGHTRNK-----------------------------STSSAMSGSHQD------------------------------LSVIQPIVKDCKEADLS-----LYNEFRLWKDEPTMDRTCPFLDKIYQEDIFPCLT---------FSKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPK--------------KCALTGQSKSCKHRIKLGDSSNYYYISPFCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J6L5-1", "uniprot_id": "A0AC58J6L5_DANRE", "id": "A0AC58J6L5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------MKIFWAMASEPLEGFHEVNLASPTTPDVHGVIDPSPPKHNAPPSTLYRTHS--LSSSQNAASALRADQLPTQPVYSAPRHLGGDDTLN-GSGNDP---------------------------------AAVDAVDAD----------------------------GEDGLGLSTDGLSRLRSPS-VMEVREKGYEKLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVHEANLKQATAEKQLK-----------------EALGKIDVLQAEVAALKTLVLSTSPTSPCKEMPPGPKAPFKKGHVRNK-----------------------------STSSAMLGSQQE------------------------------VAVTQPIVRECKEVDSL-----LFTEFKAWKEEPTLERSCSFLERIYREDIYPCLT---------FSKSELGSAILEAVEQNTLSVEPVGFQPLPVVRASAVECGGPKMAE--------TLVKCALCGQTKTCKHRIKFGDSSSYYYVSPFCRYRITSVCNFFTYIRYILQGLVKQQDAEQMFWEVLQLRKEMSNAKLGFYKDEL---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17065-1", "uniprot_id": "SEC2_YEAST", "id": "P17065-1", "name": "Rab guanine nucleotide exchange factor SEC2", "aln": "MDASEEAKRVSIQVTSLSTQLIESVDKQSHLEEQLNKSLKTIASQKAAIENYNQLKEDYNTLKRELSDRDDEVKRLREDIAKENELRTKAEEEADKLNKEVEDLTASLFDEANNMVADARKEKYAIEILNKRLTEQLREKDTLLDTLTLQLKNLKKVMHSLDNESTVTNNSNRYSTILSDSATSSSTSLNKVPTSYSLASQDIYSGIVYSPSISSIRYDISLYNEFLKFVAALPRCENIKATSTESKLIRRLVNDEIQPILKIDNASGIGWLVKKTLLSLIIDGLVVVEPLSGVNATYQIGYNSSSPAKQATSNMPKMFKFPLDSPPVAVHAACSFCGESRDDIIEHARMYILKTLHKTDDGKEQVTNTYPLCHWCLLKLRQTCEIFAFLRSLKVGAWHLEKLTTQNITKEDLEKFSEVTKHTKRDGRVSSQDKKTKRLSFMAGLGINSSTKNKPKMEIFSSETNAKPGQPTTNIQRAWLQLCKLRCILHWTHIGIWAVDDSISSKIGPLVEDDSDEDQNDAISVRLQDKALWKQDAKRPFSSSSAEESQKSDAFDFESGDMENEITGESSSDESSSDGSSTDNSTADSSSEDESSLADSTTSSADSSSPESIDNGEGDDTVTKDDKSSIKSANNNEENSDCGDKKGRSIIKKKAPQRKIQKKKLLQDLDDLEEQFREESAIDQTEFENAESNVKQNISSKRASSGDENSKKDNNEKTLKTNLTIGDKTQEQIGENSPSSGLHASSSNDDNFDDAQEQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. :. : : ::: . .: :. . . : : .: . : ::.. *:. :. : : : . . :.* *.* :.. * * . : **: . :.. .*: : :: * .::*:. * . : *:. . *:.*. .. ... :: * . : *:. .: * :.* *. : *:*.: : * : **::.. :.. :. :.* : : :.*: .*: .:.::.* . .. . ..: :*:.:...*: . : .:: ... **.. :. . * . ::: : : : : ::. :* :* : . : . :. . : ", "identical_positions": 37, "similar_positions": 160, "identity": "4.87%" }, { "cls_id": "homologset.agr.RGD:620651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61476-1", "uniprot_id": "DAF2_MOUSE", "id": "Q61476-1", "name": "Complement decay-accelerating factor transmembrane isoform", "aln": "-------------------------------------------------------MVSSTWGYDPRAGAGDLVITTTAAGAVTIAVLLFQ-TVCGDCGPP---------------------PDIPNARPILGRHSKFAEQSKVAYSCNNGFKQVPDKSNIVVCLENGQWSSHETFCEKSCDTPERLSFASLKK----EYFNMN----------------------------------------------------------------------FFP----VGTIVEYECRP-------------------------------------------------------------------------------------------------------------GFRKQPSLSG--------------------------------------------------------------------------------------------------KSTCLEDLVWSPVAQFCKKKSCPNPKDLDNGHINIPTG-ILFGSEINFSCNPGYRLVGITSILCTIIGNT---------------------------------------------------------------------------------------------------------------------------------------------------------VDWDDEFPVCTEIFCPDPPKINNG--IMRGESDSYKYS---------QVVIYSCDKGFILFGNST--------------IYCTVSKSDVGQWSSPPPQCIEESKVPIKKP----------------------------------------------------------------VVNVPSTGIPSTPQKP----------------------------------------------------------------------TTESVPNPGDQ----------------------------PTPQKPSTVKVP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATQHEPDTTT------RTSTDKGESNSGGDRYIYGFVAVIAMIDSLIIVKTLWTILSPNRRSDFQGKERKDVSK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q61475-1", "uniprot_id": "DAF1_MOUSE", "id": "Q61475-1", "name": "Complement decay-accelerating factor, GPI-anchored", "aln": "-------------------------------------------------------MIR---GRAPRTRP---SPPPPLLPLLSLSLLLLSPTVRGDCGPP---------------------PDIPNARPILGRHSKFAEQSKVAYSCNNGFKQVPDKSNIVVCLENGQWSSHETFCEKSCVAPERLSFASLKK----EYLNMN----------------------------------------------------------------------FFP----VGTIVEYECRP-------------------------------------------------------------------------------------------------------------GFRKQPPLPG--------------------------------------------------------------------------------------------------KATCLEDLVWSPVAQFCKKKSCPNPKDLDNGHINIPTG-ILFGSEINFSCNPGYRLVGVSSTFCSVTGNT---------------------------------------------------------------------------------------------------------------------------------------------------------VDWDDEFPVCTEIHCPEPPKINNG--IMRGESDSYTYS---------QVVTYSCDKGFILVGNAS--------------IYCTVSKSDVGQWSSPPPRCIEKSKVPTKKP----------------------------------------------------------------TINVPSTGTPSTPQKP----------------------------------------------------------------------TTESVPNPGDQ----------------------------PTPQKPSTVKVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATQHVPVTKTTVRHPIRTSTDKGEPNTGGDRYIYGHTCLITLT-VLHVMLSLIGYLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5XWT0-1", "uniprot_id": "A0A8I5XWT0_RAT", "id": "A0A8I5XWT0-1", "name": "", "aln": "-------------------------------------------------------MIR---TRAPGTRAP---PPPPLLLSLSLLLLLLSPTVSGDCGPP---------------------PDIPNATPNSGKHTKFAHQSQVTYSCNKGFKQIPDKPNTVVCLENDQWSNYETFCNKTCSAPLRLNYASLKK----EYRNMN----------------------------------------------------------------------FFP----IGTTVEFECRP-------------------------------------------------------------------------------------------------------------GFQKVTSRTG--------------------------------------------------------------------------------------------------KSTCLEELVWSPVVEFCKKRACPNPRELKNGHINIPTD-ILFGSEIIFSCDKGYKLVGVTSTFCSITGNA---------------------------------------------------------------------------------------------------------------------------------------------------------VDWDDVFPVCTTIFCPDPPKINNG--RIREESDSYAYR---------QSVTYSCDQGFILVGNSS--------------VHCTLN-GEVGEWSSAPPKCIERHKVPTKTPPEVDIPSTMPHESTLINFPSTRAPLSHKPTTVKVPGTRVKPTSHKPTEVKVPGTRVPPTSQKHTTVNVPSTRVPATSQKPSMVHVSDTRV------------------------------SPKPQKPTKANNPSTEIPPTPQKANTADVPSTESPPTPQKANTAVVPATEIPPAPQKTNTAVAPATEIPPTPQKTNTADVPSTESPPTPQKANTADVPATEIPPALQKANTAVVPATETLPTPQKANTAIVPATETPPAPQKTNTAVAPSTEIPPTPQKANTADVPATEIPPTPQNANTADVPSTEIPPTPQKSNTADVPATEIPPTPQKANTADVPATEIPPTPQNANTADVPSTEIPPTPQKTNTAKVSAIKPATAQMSLISTTVFAQTPPITQHPTTVNSSAVQTAQTTRGFATAKPSLTQNPPATQRPTISHFSMTKGLHTVTQIFTSAHITATQHVPVSKTTVRHPTRTSKDRGESNSGGDHFIYGHTCLITMT-ILHVMLLLTG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08174-1", "uniprot_id": "DAF_HUMAN", "id": "P08174-1", "name": "Complement decay-accelerating factor", "aln": "-------------------------------------------------------------MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLP---------------------PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQ----PYITQN----------------------------------------------------------------------YFP----VGTVVEYECRP-------------------------------------------------------------------------------------------------------------GYRREPSLSP--------------------------------------------------------------------------------------------------KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGG-ILFGATISFSCNTGYKLFGSTSSFCLISGSS---------------------------------------------------------------------------------------------------------------------------------------------------------VQWSDPLPECREIYCPAPPQIDNG--IIQGERDHYGYR---------QSVTYACNKGFTMIGEHS--------------IYCTVN-NDEGEWSGPPPECRGKS-LTSKVP--------------------------------------------------------------------PTVQKPTTVNVP----------------------------------------------------------------------TTEVSPTSQKT------------------------------TTKTTTPNAQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTG--LLGTLVTMGLLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYR4-1", "uniprot_id": "Q9VYR4_DROME", "id": "Q9VYR4-1", "name": "", "aln": "----------------------------------------MFCCNIPVDASVATSTSTSISTYPLQRATKRAMTPPNAMALIMLLLLALCAAGNGQICGP---------------------PAVP-LNAKVRTITVDSQIAEAHYECDAGYELFG--PSAVKCDRRTGWDRDLPFCGVNVAYRKPVNQSSYTRSGPASYANDGKPGNKNPDGQECSETQKEPSPWWRVDLLTPQAVHVVRITTRGCCGHQPLQDLEIRVGNSSADLQRNPLCAWYPGTLDEGVVKTFTCARPLVGQYVAIQLVGVEGSLSLCEVETFTNDEFSVDRCLSPKIGVDTVVTTFSKTCYDFHITKGESFDKAQAICKQTGGDLVHDFRGATSSYILSELERRKSELKPQLVWIGAQKEPGITSRTWKWVNGDVVQKPTWGKDQPNNYNGEQNCVVLDGGRNWLWNDVGCNLDYLHFICQHSPLSCGSPDAQQNTTVMGKKFTLGEKIQYTCPKGHSLLGQTERECRLDGTWSGSSPTCKYVDCGSLPELKFGSIHMSEERTSFGVVATYSCHENYTLIGNENRTCAMDGWSGKQPECLVDWCPDPQPIAGGDVRFNDKRAGSTATYVCEPGYVLVGEAIISCG---------------------------------------------------------------------------------------------------LGGEWSSKTPSCRFVDCGAPARPNRG--IAILLNGTTTVN---------SVVKYECDEDHWLDGQSE--------------LYCTRE----GKWSGEAPVCELVTCETPSVPSGSFVIGYDYNVHSKIQYNCDPGHIMHG---------------------TPVLECLDSGEWSADAPYCEYIDCGTILPIPYGSHKYVTNT------------------------------TYVGSEVVFSCSQSHKLSGVLKRTCLESAVWSDASPKCEEIRCPEPKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTYKIGALAKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECGAPEGINNGKVVLATNATYYGAAVLYECNVN---FKLNGVSRRLCTEHGNWSHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAKGRIMMGNDTRVCQKNGKWTGKSPTCRPVDCGRPLAIENGRVIVVNDSTLYGGSAEYHCIPNYNRIGQYLRKCTEDGAWSGKQPRCELATAEGQETSELGTGVGIGATVIVALLVIFGLIFLYRNKARPVKNTENVQAAETKDERNAAVMSYSTLEANNRMHMDNNPSATFNTFHGGAGGRSNGGGNPDANSNGERLNNNRSENI--------------YDQIPNEQFYDAPYEMRTNDEVYEPEPVASNVITINGISVR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7YZX0-1", "uniprot_id": "B7YZX0_DROME", "id": "B7YZX0-1", "name": "", "aln": "MNRLLLQCLVTTILVYKVISVPTSTMSTSIQTTSEIPQQDDDDDDWEEDDDSLESDDDGRVYKNPRNSPSTECPRDEEQATLLGQKCLRKCSSDEDCKSKKKKCLCDGVCGNSCIKPDRECPELAQPSLGQVTVAGRHFGARASYACPHGYHVVG--LQSRLCQADGNWAGAEPACKQNIYCLKPPQIEHARNSALPEQETFDLDSTVQYHCHTGYVTNGFPRAKCLAIDNLASWYGPDIQCEPRSCGQPPDPAYG----------------WHAGECYTYGCKITYNCGTG--------------------------------------------------------------------------------------------------------YELVGKHERYCQSDGSWTP-------------------------------------------KELPTCVLVTSVVCPTPENPKNGKATYTTLAYNSVVSYECRYGYTLVGESSSRCGADRKWSGTLPTCKEINCGHPGVLYNGWIENIEAGTGLGASIIFRCQPEMMINGLGSSVCQIDGRWRNALPECLAPCVVPTISQGNVYPIEIITDENGTTIVHPPTTTTQSPTQTQSIGGVEKVKHGTALEVKCDENYEFPVSLLSPPTCNNGTWSIIPRCVPARCKSMPRPPKHGMVMAPKTEHGMKARFKCKDGFKLVSPEGKDVTDPHDYVLTCSFGNWTGETPKCDEVFCSFPGYIPNGKVLLVGNMGLYDYRPYVKKIVNNKQIMYDCDKGYVLEVGPPGATCVGGKWRPLDLPQCLLGQHPRLRWNRRRRRSLQIRQLRSMYLLQRQRQLQRQLIDNQNYIKAIADPVQPSVHRVKRSASPHPNSQPYASDVDRAYSKYYQKIKERYQRYVRKMLGRDRIYQRLHSQDAVGRVGNNLNTHDGGQVTMRGKSNFREFENGNNYLGSGGIGSGGVVGSGVVALPNINQASRNHQVHVNRTPKEELLSNGSPPIASRSLHLNATRSYIEQLKSQIVRRRRRRSSSIGQSPPPSGATIPDAEVDISDGGEAGKGGGGKRLRGPCEELEWDSFANVTTVRPGKVPGRNAVGIMLHLECNAGFKLNIKGENATARCIRGIWKPETPKCLSAPCLVPAVEHGQYYKVEPHTKQLSDKPSLTPLSTYEEIQSNEFITLECEDGFNIQGSAQLRCAHGSWSVNAFSECTSVPCTLPNIPGVIYDGGYRAGLTIGHGSSVSVRCELSTNANPIEMSCHKGILTPPSIPCESGLRKSREELEHATPTPHPKVEHNELDNDHDHHDNGTDEHDDMKMCGPPMLTDGALVYKNADHPELDGAYESGTEIFFNCIPNAAGDRQTWRIICDNGLWIGRSYNCENGTCVFRNNEANVVSFYNDLEIREDVVDFPPGATIISRCMDIGKFSFMGSHERTCIHSEWTNTKPVCSGLNQENDYAMEKAPTILFRHQNGPIAQSNDGKLIVYPGTTLHMECLWMRRFGNPKWNVSHTHKNYTEGWVTEADEGRDSTLEYRLSIVDAASDDSGFYSCMTPARHEHTVEVVVRAINCPEIPMRRGLIVNTNDTKLSTRALLSCANGNSLIGASELFCLPSGNWSAPLPVCESVECGDIPLGMGSNASSPRVSVLSREVGGRAAFSCASGYGLRGPAEAICNPTGEWSAPLPTCVEVQCDNPGAPQNGYAQGSAPYRAGDVVQFNCNPEYMMQGQPIIACQDNARWSGGLPKCVQACSYPGTVISGRMSSVKFYYAIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTCVTNEGPVGGGGGGGGGGGGGSGSVATNKHLATTMG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * :. : : * * .: . . * * * . . . . . * : * * :. . . * : ** ** * : * *. :* : *. : * . * : * :* . * * : * * .* . . : * *::.. : * .*. . : *. : . . * . . . . ", "identical_positions": 34, "similar_positions": 54, "identity": "1.85%" }, { "cls_id": "homologset.agr.RGD:620652", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63618-1", "uniprot_id": "ESPN_RAT", "id": "Q63618-1", "name": "Espin", "aln": "MALEQAMQAARRGDLDVLRSLHAAGLLGPSLRDPLDALPVHHAARSGKLHCLRYLVEEVALPAVSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVNWLLYQGGANSAITTDTGALPIHYAAAKGDLPSMKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVSF-EQDHDGATAMHFAASRGHTKVLSWLLLHGAEISQDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLADFNGHTHCSRYLRTVQTLSLEHRVLSRDPSMDLEAKQPDSGMSSPNTTMS--VQPP-NFDLGSPTSTLSNYDSCSSSHSSSKGQR-------STR---GARSSDLQSYMDMLNPE---PRSKQGKPSSLPPPPP--PSFPPPPPP--GTQLPPPPPGYPAPNPPVGLHLDNIYMQTKNKLRHVEVDSLKK----------EPSSGDGYSGLRRQDSGLLRQDSELL-----LRHNTGLRRQDSDRKQRSFSKQPSTGDYYRQLGRSPGEPLAARPGMAHSEEA------------------------------ALLPGNHVHNGCSADSK-ASRELPPPPPPPP--LPEALSSPPPAPPLPIEG--------AGAACGQRRSSSSTG------------------------STKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGSGQPASQPESP----------------QPAVSPGPSRARSPTPPASGPQP----------LLNGSIVPAPPATLAPGVHLDVEALIPTLDEQGRPIPEWKRQVMVRKLQQKMQEEEEQRRKEEEEEARLASLPAWRRDILRKKLEEEREQKRKEEERQKLEEIQRAKEQSEKLRTLGYDEAKLAPWQRQVILKKGEIPK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ET47-1", "uniprot_id": "ESPN_MOUSE", "id": "Q9ET47-1", "name": "Espin", "aln": "MALEQALQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEISQDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHTHCSRYLRTVQTLSLEHRVLSRDQSMDLEAKQLDSGMSSPNTTMS--VQPM-TFDLGSPTSTFSNYDSCSSSHSSSKGQR-------SNRGIPGARAADLQSYMDMLNPEKSLPRGKLGKPSPPPPPPPPPPSFPPPPPPT-GTQPPPPPPGYPAPNPPVGLHLNNIYMQTKNKLRHVEVDSLKEPKVELNDQFAQPSSGDGHSGLHRQDSGLLRQDSELLHRQELLRHSTGLRRQDSDRKQRSFSKQPSTGDYYRQLGRSPGEPLAARPGMAHSEEA------------------------------ALLPGNHVHNGCSADSK-ASRELPPPPPPPP--LPEALSSPPPAPPLPIEG--------AGAACGQRRSSSSTGK---------------VRVLRHRKSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGSGQPASQPESP----------------QPLVSPAPSRTRSPTPPASGSQP----------LLNGSVVPAPPATPAPGVHLDVEALIPTLDEQGRPIPEWKRQVMVRKLQQKMQEEEEQRRKEEEEEARLASLPAWRRDILRKKLEEEREQKRKEEERQKLEEIQRAKEQSEKLRTLGYDEAKLAPWQRQVILKKGEIPK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B1AK53-1", "uniprot_id": "ESPN_HUMAN", "id": "B1AK53-1", "name": "Espin", "aln": "MALEQALQAARQGELDVLRSLHAAGLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAALPAAARARNGATPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLSDFNGHSHCTRYLRTVENLSVEHRVLSRDPSAELEAKQPDSGMSSPNTTVS--VQPL-NFDLSSPTSTLSNYDSCSSSHSSIKGQH-------PPCGLSSARAADIQSYMDMLNPELGLPRGTIGKPT--PPPPP--PSFPPPPPPP-GTQLPPPPPGYPAPKPPVGPQAADIYMQTKNKLRHVETEALKK----------ELSSCDGHD---------------------------GLRRQDSSRKPRAFSKQPSTGDYYRQLGRCPGETLAARPGMAHSEEVRARQPARAGCPRLGPAARGSLEGPSAPPQAALLPGNHVPNGCAADPK-ASRELPPPPPPPPPPLPEAASSPPPAPPLPLES--------AGPGCGQRRSSSSTG------------------------STKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGIGQPAFQPDSP----------------LPSVSPALSPVRSPTPPAAGFQP----------LLNGSLVPVPPTTPAPGVQLDVEALIPTHDEQGRPIPEWKRQVMVRKMQLKMQEEEEQRRKEEEEEARLASMPAWRRDLLRKKLEEEREQKRKEEERQKQEELRREKEQSEKLRTLGYDESKLAPWQRQVILKKGDIAKY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G7W5-1", "uniprot_id": "A0AC58G7W5_DANRE", "id": "A0AC58G7W5-1", "name": "", "aln": "MVVERTLLAARQGDVQTLKVQFAEKVLNGDVKDVLGATPVHHAARAGKLTCLRYLVDEAGLPANSLARNGASPAHDAAATGNLTCLQWLVTHGGCRAADKDSSGATVLHLASRFSHHEIIDWLLKSEEGDPTVATDTGALPVHYAAAKGDLPSLRLLLEHSPQVVNFQTKNGATPLYLACQEGHLEVVQYLVKDCGAEPSIRANDGMTPLHAAAQMGHNTVIVWLMSFTEISLSDRDNDGATAMHFAASRGHAKVLSWLLLHGGEIMTDSWGGTPLHDAAENGELECCQILVVNGVDLGIRDQDGFSAADLAEYNGHQQCAKYLRTVENMSVEHRVLSRDASADLEYKQPDSGLSSPNATLPNPAPPAGHFDICSPSSSLSNYDSANSSQSSTGEKRSGSPPSRVPTGGTDSAITDMQTYMDMLNPDEACGSHNAKEAAHLPPPPT----FPPPPPPSNPSHIPPPPPAYPAPNPPEEEEVSAEYLKVKRNLRRVDNDVVKK---------EQLNPGENHER---------------------------LRRVDSNRKSRSFSKQPSTGDYYKTLGSDTTDQQPSR-AMAPNEEG-----------------------------SALLEEAADTAPAPENGTGTTEDLPLPPPPPPPPASTFIPAPPPPPPLPSELPPPPPPSTTTPAAAQRRMSSSSNKGHLSSTHLSPSVAPAPETLRQRKSNKSFNMMSPTGDNSELLAEIKAGKSLKPTPHSKGYTTVFSNSGTPGNNGESPSSPPEPLPKPNDTQSAKPESPPPACPPTPPNPTASRSSPQNLSTSQSSDQLTAAVNGNTSVVQNKTSVVDVESLVPTHDEQGRAIPEWKRQVMVRKLQVKMQEEEENKRKAEEEAARLASLPAWRRDIMKKKLEEEKEQKRKDEEQRRMEKESEEKSELERLRTLGYDETKLAPWQKQIILKKGDIAKQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:*::: ***:*:::.*: .* :*. .::* *.* *******:*** ***:**:*..*** : *****:*****:*** *:*****:::****. :**.*********:**.* :::.*** .:.: :** ****:********:**::**: * *: ** **:*****************.:***::*.*:* **:**************..*:***:* :::*: ::*:**************:**********.** * *********************.***. *.:**:**::****:::*** :*::*****:.:*:******** * :** ** ***:****:*:. . * **: **:*::*****..**:** :: .: :*:*:*******: . :.: ****. ******* :: *****.****:** . *::.*.:**:*: : :*: : .. :.:. *** **.** *:***********: ** . : .:* .** .** *** .. : . ::.:** ****** . .:***.**** * : ....*** ***:. *.*****************************:*** *****. * *. : :** * .* . .*.*.*: .* *..:: .... :***:*:** *****.************:* *******::** *** *****:******:::******:*****:**::: *: . *.: *:********:******:*:*****:*.* ", "identical_positions": 469, "similar_positions": 211, "identity": "48.6%" }, { "cls_id": "homologset.agr.RGD:620653", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99J27-1", "uniprot_id": "ACATN_MOUSE", "id": "Q99J27-1", "name": "Acetyl-coenzyme A transporter 1", "aln": "MSPTISHKDSSRQRRSGMFSHALDMKSGPLPPGGWDDSRRDSVGGEGDREVLLGDAGPGDLPKAPRS--YRSELSSILLLLFLYVLQGIPLGLAGSIPLILQS---KNVSYTDQAFFSFVFWPFSLKLLWAPLVDAVYFKNFGRRKSWLVPTQYTLGIFMIYLSTQVDR------------LLGNIDGRTPDVVALTVTFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENR---------------------------EASIVKEETQGITDTYKLLFSIIKMPAVLAFCLLILTSKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLLISKYTAGPQPLNIFYKAMPYR------------------------LLLGLEYALLVWWTPKVEHQGGFPLYYYIIVLLSYALHQVTLYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPDA---IELCKKLGGSCVTALDGYYVESIICVLIGFGWWF-FLGPKFKKLQDEGPSSWKCKRNN----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYY8-1", "uniprot_id": "ACATN_RAT", "id": "Q6AYY8-1", "name": "Acetyl-coenzyme A transporter 1", "aln": "MSPTISHKDNSRQRRSGMFGHALDMKSGPLPPGGWDDNHQDSVGGEGDREVLLGDVGPGDFPKAKRS--YRAELSSILLLLFLYVLQGIPLGLAGSIPLILQS---KNVSYTDQAFFSFVFWPFSLKLLWAPLVDAVYFKNFGRRKSWLVPTQYILGIFMIYLSTQVDR------------LLGNIDGRTPDVVALTVTFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKETR---------------------------EASVVKEETQGITDTYKLLFSIIKMPAVLAFCLLILTSKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLLISKYTAGPQPLNIFYKAMPYR------------------------LLLGLEYALLVWWTPKVEHQGGFPIYYYIIVLLSYALHQVTLYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPEA---IELCKKLGGSCVTALDGYYVESIVCVLIGFGWWF-FLGPKFKKLQDEGPSSWKCKRTN----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00400-1", "uniprot_id": "ACATN_HUMAN", "id": "O00400-1", "name": "Acetyl-coenzyme A transporter 1", "aln": "MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGDFLKAPQS--FRAELSSILLLLFLYVLQGIPLGLAGSIPLILQS---KNVSYTDQAFFSFVFWPFSLKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDR------------LLGNTDDRTPDVIALTVAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKEN----------------------------EVSVVKEETQGITDTYKLLFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLIISKYTAGPQPLNTFYKAMPYR------------------------LLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYALHQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPDA---VELCKKLGGSCVTALDGYYVESIICVFIGFGWWF-FLGPKFKKLQDEGSSSWKCKRNN----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A4D6K3L8-1", "uniprot_id": "A0A4D6K3L8_DROME", "id": "A0A4D6K3L8-1", "name": "Acetyl-coenzyme A transporter 1", "aln": "MS--------AIRRKP--------------------------TGSNADQELLIDEPPKSEKVAEHQKPDIRGDRRNIAILLFLYVLQGIPIGLIAAIPMLLQN---RGASYKQQAEFSFAYWPFSLKLLWAPIVDSLYIRRFGRRKSWLVPVQYLLGAFMLLLSLHVDR------------WLG-GNGVDPNVPLLTLLFFLLNFLAATQDIAVDGWALTMLKRCNVGYASTCNSVGQTAGYFLGYVVFIALESKDFCNTYIRDVPLEDGMITLPRFLWFWGITFVVATTLVAIFKKENDIEDAH---------------------MDARYTEEHELNIHESYKILWDMVCMRPVQILAVILLTVKVTFAASDAVTSLKLIDAGVPKDKLALLAIPLIPLQLILPLAVGRYTNGPRPMDVYLKAIPYR------------------------IIMATVATGLAYITPYIVRGGAVPAYYYVLLITSYAIYQVFLYSMFVAAMAFFAKISDPAVGGTYMTFLNTLCNLGGNWPNTVVLWLVDVLTWKQCSNNAENTCQGKEE---QQSCEASAGKCEITFDGYYLESGICVLYGIVWLL-LVRKWIVYLQDLPVRSWLVVKQKSRXQSIV---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38317-1", "uniprot_id": "YB69_YEAST", "id": "P38317-1", "name": "Uncharacterized protein YBR219C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLLNTLSNFGGTWPRLIIMSMINYFTVYQCTIPGTNKVYVTHGGSMQACTELLNGTVTILRDGYYITNLICIVVGLFLYFGYLKRKILHLQSLPISSWRFFHFFFTILAVTSRAIYYKSQNWRREC", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38318-1", "uniprot_id": "YB70_YEAST", "id": "P38318-1", "name": "Uncharacterized membrane protein YBR220C", "aln": "-----------------------------------------------------------MEPKRKSGSLAKHDLPQFYLLIMLYLAQGIPVGLAFGTVPFLLKSLAKETSFTSLGIFSMATYPYSLKIIWSPIVDSLYNKRIGRRRSWIIPVQFVSGFVLWALGWCISQGIIFDGVDDAFHNRGNGTLHSVSIKNLTWWFGLLVFLCATQDIAVDGWALTILSKESLSYASTAQTIGLNIGYFMSFTIFLSLNSSDFANKYFRNIPLDHGFISLGGYMKFSGMLYIVITIYIIFCTKEKPYVEYLPKVEPINTSDGGSKPISIEYDDGDVVSTQNTSSIKYIYRCFIKVLKLKSVRSLAFIHMISKFAFQCNEAATNLKLLEQGFKREDLAVTVLIDLPFEIIFGYYVVKWSSDKDPMIRDNRRLRNSTGTNKVIKFLVGDAGVLTPWLWGFLGRLAAAVLGSYVVKQFPKDGEISTGYFCLVIFQHLLGSFMNTVQFIGISAFHTRVADPVLGGTYMTLLNTLSNFGGTWPRLIIMSMINYFTVYQCTIPGTNKVYVTHGGSMQACTELLNGTVTILRDGYYITNLICIVVGLFLYFGYLKRKILHLQSLPISSWRCT-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:***:.*:**.** : : ::: :* :* . :. . : *. ****: . :*:. *: : : : **. ** ", "identical_positions": 23, "similar_positions": 28, "identity": "3.57%" }, { "cls_id": "homologset.agr.RGD:620654", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHJ4-1", "uniprot_id": "TM11D_RAT", "id": "Q8VHJ4-1", "name": "Transmembrane protease serine 11D", "aln": "-----------------------------------------------------------------MYRPRSMVSPSRFFNPFMVALIVIITVG-------------------------------LLAMTAGLLIHFLAFDKRAYFYHSNFHILNVDYTEALNSPATHEYRTLSERIESMITDAFRESNLRSEFIRTHVVKLRKEGSGVVADVVMKFRSSKRNNKKA---------------------------------IKTRIQSVLQR-LSSSGNLEIAPSNGITSLTDQDTENVLTQECGARPDLITLSEERIIGGTQAETGDWPWQVSLQLN----NVHHCGGTLISNLWVLTAAHCFRSYSNPQQWTAT-------------------FGVSTISPRLRVRVRAILAHAEYNSIT--RDNDIAVVQLDRPVTFTRNIHRVCLPAAT--QNIMPDSVAYVTGWGSLTYGG----NTVT-NLQQGEVRIVSSEVCNEPAGYGG--SVLPG-MLCAGVRSGAVDACQGDSGGPLVQEDTRR-LWFVVGIVSWG-YQCGLPNKPGVYTRVTAYRNWIRQQTGI------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHK8-1", "uniprot_id": "TM11D_MOUSE", "id": "Q8VHK8-1", "name": "Transmembrane protease serine 11D", "aln": "-----------------------------------------------------------------MYRPRPMLSPSRFFTPFAVAFVVIITVG-------------------------------LLAMMAGLLIHFLAFDKKAYFYHSSFQILNVEYTEALNSPATHEYRTLSERIEAMITDEFRGSSLKSEFIRTHVVKLRKEGTGVVADVVMKFRSSKRNNRKV---------------------------------MKTRIQSVLRR-LSSSGNLEIAPSNEITSLTDQDTENVLTQECGARPDLITLSEERIIGGMQAEPGDWPWQVSLQLN----NVHHCGGALISNMWVLTAAHCFKSYPNPQYWTAT-------------------FGVSTMSPRLRVRVRAILAHDGYSSVT--RDNDIAVVQLDRSVAFSRNIHRVCLPAAT--QNIIPGSVAYVTGWGSLTYGG----NAVT-NLRQGEVRIISSEECNTPAGYSG--SVLPG-MLCAGMRSGAVDACQGDSGGPLVQEDSRR-LWFVVGIVSWG-YQCGLPNKPGVYTRVTAYRNWIRQQTGI------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60235-1", "uniprot_id": "TM11D_HUMAN", "id": "O60235-1", "name": "Transmembrane protease serine 11D", "aln": "-----------------------------------------------------------------MYRPARVTSTSRFLNPYVVCFIVVAGVV-------------------------------ILAVTIALLVYFLAFDQKSYFYRSSFQLLNVEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKFQFTRNNNGAS---------------------------------MKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLN----NAHHCGGSLINNMWILTAAHCFRSNSNPRDWIAT-------------------SGISTTFPKLRMRVRNILIHNNYKSAT--HENDIALVRLENSVTFTKDIHSVCLPAAT--QNIPPGSTAYVTGWGAQEYAG----HTVP-ELRQGQVRIISNDVCNAPHSYNG--AILSG-MLCAGVPQGGVDACQGDSGGPLVQEDSRR-LWFIVGIVSWG-DQCGLPDKPGVYTRVTAYLDWIRQQTGI------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQA3-1", "uniprot_id": "Q9VQA3_DROME", "id": "Q9VQA3-1", "name": "trypsin", "aln": "--------------------------------------------------------------------------------------MLLKGIL-------------------------------LLVSIAQIAADFKSIG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IEQAPWQASVQIN----DKHHCGGVIYSEDIILTIAECVR---KARLEFIS-------------------VRVGSAQENAGGTVLKVEKMRLQVLGL--RPSDVAILQLRSPLYLDGGIR--AIPLAT--IPLVPGTNASVSGWGQLSAMN----PSSE-VLLRVDVKIQDQLMCATNLALKG--RLMSVGEICAAPAGEIPYACQGFVGGPLVANNR------LYGILSWQ-SACDVLNKSSVYANIAMFKVWIESTVKLMNFFRIG-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8DY75-1", "uniprot_id": "A8DY75_DROME", "id": "A8DY75-1", "name": "Peptidase S1 domain-containing protein", "aln": "MLPLPRHSKDTWLRLVVLCALICLSAPRRADALGYPSAQQEHDMLILDALSRRSGTGYYGENSVMEMLSRMIPQSCRFRGHKFECGLSISCVLGGGKPLDLCSGGMIWSCCVDKDLDAEESPHAAPVNNTSDIIHLHDIYPDLSTNANKPQHHLHHHSGNGLSAAPSTSSTASSSARPAYPSSYYGTKRPTHYSGSNPYKPGSSAGGSSRPSSSSSSSLNSWEHETGGHLGSISGITNHLDSFFDAESQAPLDSAGAPPPHEPLPNAQAFAVGNVLDLNAGEAADEYQSGGSGGYHDASYRPVPGCGEVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPNSNMKIRLGEWD--------------VRGQEERLNHEEYGIERKEVHPHYNPAD--FVNDVALIRLDRNVVYKQHIIPVCLPPST--TKLT-GKMATVAGWGRTRHGQ----STVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAGYKDGGRDSCQGDSGGPLTLTMDGR-K-TLIGLVSWG-IGCGREHLPGVYTNIQRFVPWINKVMANDNA---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA88-1", "uniprot_id": "Q9VA88_DROME", "id": "Q9VA88-1", "name": "CLIP domain-containing serine protease", "aln": "-----------------------------------------------------------------------------MLGSVLRLWILFGCFYR-------------------------------FLALAEVLQECDIPNETKRGVCLEVSRCKAYLQVRNATNLPAEKVNFLKKVQCEVEQQVSEAQGSYESLVCCPANGQDYLFPVLQFSKFEYR----------------------------------------------------RFLDVTARFKRKKLKRRIQTVEPSSGFNLLNECG------KQVTNRIYGGEIAELDEFPWLALLVYN---SNDYGCSGALIDDRHILTAAHCVQGEGVRDRQGLKHVRLGEFNVKTEPDCIEEPNYLSCADAALDIAYEKIHVHPEYKEFSNYKYNDIAIIRLKHPVSFTHFVMPICLPNKSEPLTLAEGQMFSVSGWGRTDLFNKYFINIHSPIKLKLRIPYVSNENCTKILEGFG--VRLGPKQICAGG-EFAKDTCAGDSGGPLMYFDRQHSRWVAYGVVSYGFTQCGMAGKPAVYTNVAEYTDWIDSVVQQRKKSQQTQDKMA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . ** . : . *.* : .: ::* *.*. .*:*:::* : : .:* : : . *:*** . : .. * * : :**. :* * **** *::*: *. ..**:.: : ** . ", "identical_positions": 32, "similar_positions": 47, "identity": "5.37%" }, { "cls_id": "homologset.agr.RGD:620655", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q58NB6-1", "uniprot_id": "DHRS9_MOUSE", "id": "Q58NB6-1", "name": "Dehydrogenase/reductase SDR family member 9", "aln": "MLFWLLALLFLCAFLWNYKGQLKIADIADKYVFITGCDTGFGNLAARTFDKKGFRVIAACLTESGSAALKAKTSERLHTVLLDVTDPENVKKTAQWVKSHVGEKGLWGLINNAGVLGVLAPTDWLTVDDYREPIEVNLFGLINVTLNMLPLVKKARGRVINVSSIGGRLAFGGGGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTELADPIKTTEKKLAIWKHLSPDIKQQYGEGYIEKSLHRLKSNTSSVNLDLSLVVGCMDHALTSLFPKTRYIAGKDAKTFWIPLSHMPAVLQDFLLLKQKVELANPKAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VD48-1", "uniprot_id": "DHRS9_RAT", "id": "Q8VD48-1", "name": "Dehydrogenase/reductase SDR family member 9", "aln": "MLLWVLALLFLCAFLWNYKGQLKIADIADKYIFITGCDSGFGNLAARTFDRKGFRVIAACLTESGSEALKAKTSERLHTVLLDVTNPENVKETAQWVKSHVGEKGLWGLINNAGVLGVLAPTDWLTVDDYREPIEVNLFGLINVTLNMLPLVKKARGRVINVSSIGGRLAFGGGGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTGLADPIKTTEKKLAIWKHLSPDIKQQYGEGYIEKSLHRLKSSTSSVNLDLSLVVECMDHALTSLFPKTRYTAGKDAKTFWIPLSHMPAALQDFLLLKEKVELANPQAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BPW9-1", "uniprot_id": "DHRS9_HUMAN", "id": "Q9BPW9-1", "name": "Dehydrogenase/reductase SDR family member 9", "aln": "MLFWVLGLLILCGFLWTRKGKLKIEDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGGGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTNLADPVKVIEKKLAIWEQLSPDIKQQYGEGYIEKSLDKLKGNKSYVNMDLSPVVECMDHALTSLFPKTHYAAGKDAKIFWIPLSHMPAALQDFLLLKQKAELANPKAV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*:*.**:**.***. **:*** **:***:******:***********:***:*********** ****:*****:*******:*****.******.:*************** **********::**************.************:********:*****: *************************************** ****:*. *******::******************.:**...* **:*** ** *************:* ****** **********.********:*.*****:**", "identical_positions": 268, "similar_positions": 39, "identity": "84.01%" }, { "cls_id": "homologset.agr.RGD:620656", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88277-1", "uniprot_id": "FAT2_RAT", "id": "O88277-1", "name": "Protocadherin Fat 2", "aln": "----------MTLVLLGLAILLLHRAACEKSLEETIPPLS-------------------WRFTHSLYNATIYENSAPKTYVESPVKMGMYLAEP--HWVVKYRIISGDAAGVFKTEEHVVGNFCFLRIRTKSSNTALLNREVRDSYTLIVQASD-----KSLEFEALTQVVVHILDQNDLKPLFSPPSYRVTISEDRPLKSPICKVTATDADLGQNAEFYYAFNARSEVFAIHPTSGVVTVAGKLNVTRRGKYELQVLAVDRMRKISEGNGFGNLASLVIRVEPVHRKPPAINLVVLNPPE-GDEGDIYAIVTVDTNGS--GAEVDSLEVVGGDPGKYFKVLRSYAQGNEFNLVAVRDINWAEHPHGFNISLQTHSWSRFPPHSIIRAFHLPSWKLANLRFEKAVYRVKLSEFSPPGSRVALVKVTTALP----NLRYSLKPSSRNTAFKLNARTGLITTTKLVDFHEQNQYQLHVKTSLGQ-------ATTTVIIDIVDCNNHAPVFNRSSYEGTLDENIPPGTSVLTVTATDQDHGDNGHITYSIAGPKAVPFSIDPLLGVISTTKPMDYELMKRIYTFRVRASDWGSPFRQEKEVSVSLRLKNLNDNQPMFEEVNCTVSLRQDVPVGKSIMAVSAIDMDELQNLKYEIVSGNEQDYFHLNHFSGVISLKRSFMNLTAVRPTIYSLKITASDGKNYASPTTLKVTVVKDPHSE--------VPVQCDKTGVLTHITKTILQSAGLQSQELGEEEFTSLSN----YQINHHSPQFEDHFPQSIDILEQVPINTPLARLAATDPDTGFHGKLVYVISDGNEEGCFDIELETGLLMVAAALDYETTSFYVLNVTVYDLGTPPKSSWKLLTVTVKDWNDNPPRFPPGGYQLTISEDTEVGTTIAELKTEDADSEDNRRVRYTLLTPTEKFSLHPFTGELVVTGHLDRESESQYILKAEARDQPTKGHQLFSVTDLIVTLEDINDNPPQCITEHRRLKVPEDMPLGTVLTFLDASDPDLGPAGEVKYILVEDAHG--TFQVHPMTGALSLEKELDFERRAGYNLSFWASDSGKPLSRRTLCHVEVLVMDVNENLHSPHFSSFVYQGQVQENSPAGTPVMVVTAQDDD-SGLDGELQYFLRAGTGLETFSINQDTGMLETLAPLDREFTPYYWLTVLAVDRGSVPLSAVTEVYIEVTDINDNIPSMSRPVFYPSVLEDAPLGTSVLQLEAWDPDSSSQGKLTFNLTSGNHLGHFIVHPFTGLLT-TAKQLDRENKDEYVLEVTVQDNGDPSLRSTSRVVVCILDVNDNPPMFSHKLFNVRLSERLSPLSPEPVYRLVASDPDEGLNGSVTYSIEESD-EESFRIDPVTGVVSSSSTFAAGEYNILTIKATDSGQPALSTSVRLHIEWIPQ-PRPSSIPLSFDESYYSFTVMETDPVN--HMVGVISVEGRPGLFWFHISDGDKDMDFDIEKTTGSIVIARPLDTRRKSSYNLTVEVTDGFHTIATQVHIFMIANINHHRPQFLQDHYEIRVPQDTLPGVELLRVQATDQDHGKGLIYTILSSQDPGSANLFQLDPSSGVLVTVGTLELHSGPSQHILTVMVRDQEMPIKRNFVWVTIHVEDGNLHSPHFTQLRYEANVPDTTAPGTELLQVRAVDADRGANAEIHYSFLKGNSDGFFNIDSLLGIITVAQRLYHVHLTRHALTVKAEDQGSPRRHDLALVVIHVHPSDSSAPVFSKDEYFIEIPESVPIGSPILLLSAGSSSEVTYELREGNKDSVFSMNSYSGLISTQKRLDHEKVPSYRLRIRGSNMAGVFTEVVALVYIIDENDNPPAFGKPTFLGHISEAAPLHSLILGEDNSP---LVVRASDSDREANSLLVYKILEPEALKFFKIDPSMGTLTTTSELDFEDTPLFQFNIYVHDQGTPILFAPRSAKVIIHVRDVNDSPPRFSEQIYEVAVVEPIHPGMGLLTVQAEDND-SRVTYSIKTSNADEAVTIHPTTGQISVVNPATLR----LFQKFSIRASDGLYHDTAVVKISLTQVLDKSLQFDQDVYRARVTENTPHRKALVILGVHGNHLNDTLSYFLLNGTDLFHMIESAGVLQTRGGTFDREQQDTHEVAVEVR-----DNRVPQRVAQALVRVSVEDVNDNIPEFQHLPYYTVIQDGTEPGDVLFQVSATDKDLGANGSVTYGFAEDY-AYFRIDPYVGDISLKKPFDYQALNKYHLRVIARDSGIPPLQTEVEVHVTVRNKSNPLFQSPYYKVKVPENITLYTPILH-TQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKNKHVFTVRATDTALGSFSEATVEVLVEDINDNPPTFSQLVYTTSVSEGSPAQTPVIQLLASDQDSGQNQDVSYQIVED-GSDVSKFFRINGSTGEIFTIQELDYETHQHFRVKVRAMDKGDPPLTGETLVVVNVSDINDNPPKFREPQYEANVSELATCGHLVLKVQALDPDIGDTSRLEYLILSGNQDRHFSINSTSGIISMFNLCKKQLDSSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQNVYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGERFFINPR-GQITTLQKLDRENSTERVIAIKVMARDGGGKVAFCTVKIILTDENDNAPQFKASGYTVSIPSNVSRDSPIIQVLAYDADEGRNADVTYSVDS--TEDLAEEIIEVNPTTGVVKVKESLVGLENRAVDFNIKAQDGGPPHWDSLVPVRLQVVPNEIPLPKFSEPLYTFSAPEDLPEGSEIGSVKAVAAQDPIIYSLVQGTTPESNSDDVFSLDQDTGVLKVRKAMDHESTKWYQIDLMAHCPHEDTDLVSLVSVSIQVEDVNDNRPVFEADPYKAFLTENMPGGTTVIQVTANDQDTGSDGQVSYRLSVEPGSNIHELFAVDSESGWITTLQELDCETQQTYRFYVVAFDHGQTIQLSSQALVEVSITDENDNPPRFASEDYRGSVVENNEPGELVATLKTLDADVSDQNRQVTCYITEGDPLGQFSISQVGDEWRISSRKTLDREHIAKYLLRVTASDGKFQASVPVEVFVVDINDNSPQCSQLLYTGKVREDVTPGHFILKVSAIDVDMDTNAQITYSLHGPGAQEFKLDPHTGELTTLTVLDRERKDVYNLVAKATDGG--GQSCQAEVTLHIEDVNDNAPRFFPSHCDVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLTDSADGQFSIDATSGVIRLEKPLQVRASSAVELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPIFLNAEHSTQVPEDAPIDMEVLHLATLTRPG--SEKTGYHITGGNEQGKFRLDAHTGILYVNGSLDFETNPKYFLSIECSRKSSSSLSDVTTIVINVTDVNEHHPRFTHDLYTVRVLENAVVGDVILTVSASDDDGPVNSAITYSLVGGNQLGHFTINPKKGKLQVAKALDWEQTPSYSLRLRATDSGQPPLHEDTEVAVEVVDVNDNPPRFFQLNYSTSVQENSPIGIKVLQLILDDPDSPQNGPPYFFRITEGNTGSVFRVTPDGWLVTAASLSKKAREWYQLHIEVSDSGLPPLSSSTLVRVQVTEQSRYPPSTLPLEISITKGEEEFQGGMIGKIHATDRDPQDTLTYSLEQEGG----LDRYFTVGASDGKIIASQGLPHGRYSFNVTVSDGTFTTTTGVHVHVWHMEPEVPQQAVWLGFHQLTPEELVSDHWRNLQRFLSNLLDVKRANIHLASLQPAEVTAGVDVLLVFER--------------------HSGTSYDLQELASAIAHSVREIEHSVGIRMRSALP-VVPCQGQSCQDQTCQETVSLEPRVGPSYSTARLSILTPRHHLGRNCSCNG----------------------------------------------------------------TTLRFSGQSYVQYRPLEAQN-------WQIHFYLKTLQPWALLMFTN-ETASISLKLANGFSHLEYHCPGGFYGNLSSRYPVNDGQWHSMLLEERDTSVHLLVDITDNASLVIPEECQGLRTE-RQLLLGGLVPSNPSSN----VSLGFEGCLDAVVVNGERLELLGREKKMEGRLETWALSQCCWPG-------TACSQSPCLNGGSCSPALGSGYLCRCPPPFSGRNCELGRENCTSAPCQEGGTCVSS-PEGTSCNCPHPYTG------------------------------------DRCEMEARGCSGGHC---------------------------------LITPEIKRGDWGQQEFLVITVALPLVIIATVGLLLYCRRRKSHKPVTMEDPD---------LLARSIGVDTQASPAIELDPLNTSS------------------------------------------------------------------------CNNLNQPEPSKTSVPNELVT-FGPSSKQRPMVCSVPPRLPPAAVSSHP---GHEPIIKRTWSGEELVYPSGAAVWPPTYSRKKHWEYPHPETMQGTLPPSPRRHVGPAVMPDPTGLYGGFPFPLELENKRAPLPPRYSNQNLEDLMPPRP--------------------------PSPREHLLAPCLNEYTAISYYHSQFRQGGGGPCLAEGGYKGVSMRLSRAGPSYADCEVNGGPATGRSQPRAPPNYEGSDMVESDYGSCEEVMF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5F226-1", "uniprot_id": "FAT2_MOUSE", "id": "Q5F226-1", "name": "Protocadherin Fat 2", "aln": "----------MTLVLLGVAMVLLHRAACEKPLEETITPLT-------------------WRFTHSLYNATIYENSAPKTYVESPVKMGMYLAEP--HWVVKYRIISGDAAGVFKTEEHVVGNFCFLRIRTKSSNTALLNREVRDSYTLVVQASD-----KSLEFEALTQVVVHILDQNDLKPLFSPPSYRFTISEDRPLKSPICKVTATDADLGQNAEFYYAFNARSEVFAIHPTSGVVTVAGKLNVTWRGKYELQVLAVDRMRKISEGNGFGNLAPLVIYVEPVHRKPPVITLVVLNPPE-GDEGDIYATVTVDTNGS--GAEVDSLEVVGGDPGKYFKVLKSYAQGNEFNLVAVRDINWAEHLHGFNISLQTHSRSRFPSRSIIRAFHLPPYTLANLRFEKAVYRVKLSEFSPPGSRVALVRVTTALP----TLRYALKPSSGSTVFKLNARTGLITTTKPVDFHEQNQYQLHVKTSLGQ-------ATTTVIIDIVDCNNHAPVFNRSSYEGTLDENIPPGTSVLTVTATDQDHGDNGHITYSIAGPKAVPFSIDPYLGVISTTKSMDYELMKRIYTFRVRASDWGSPFRQEKEVSVSLRLKNLNDNQPMFEEVNCTVSLRQDAPVGKSIMAVSAIDMDELQNLKYEIVSGNEQDYFHLNHFSGVISLKRSFMNLTAVRPTVYSLKITASDGKNYASPTTLKVTVVKDPRSE--------VPVQCDKTGVLTHITKTILQSAGLQGQEMGEEDFTSLGN----YQINHHAPQFEDHFPQSIDILEQVPVNTPLAHLAATDPDPGFHGRLVYVIADGNEEGCFDIELETGLLTVAAALDYETTSFYVLNVTVYDLGTPPKSSWKLLTVTVKDWNDKPPRFPPGGYQLTISEDTEVGTTVAELKTRDTDSEDNGRVRYTLLTPTEKFSLHPLTGELVVTGQLDRESEPQYILKAEARDQPTKGHQLFSVTDVIVTLEDINDNPPQCITEHSSLKVPEDMPLGTVLTFLDASDPDLGPAGEVKYILVDDVHG--TFRVDPMTGALSLEKELDFERRAGYNLSFWASDSGRPLARRTLCHVEVLVMDVNENLHSPHFSSFVYQGQVQENSPAGTQVMVVTAQDDD-SGLDGELQYFLRAGTGLEAFSINQDTGMLETLAPLDREFTPYYWLTVLAVDRGSVPLSAVTEVYIEVTDINDNIPSMSRPVFYPSVKEDAPLGTSVLQLEAWDPDFSSQGKLTFNLTSGNHMGHFIVHPFTGLLS-TAKQLDRENKDEYVLEVTVQDNGDPPLRSTSRVVVCVLDVNDNSPMFSHKLFNVRLSERLSPLSPEPVYRLVASDPDEGLNGSITYSIEESD-EESFRIDPVTGVVSSSSTFAAGEYNILTIKATDSGQPALSTSVRLHIEWIPQ-PRPSSIPLSFDESHYSFAVMETDPVN--HMLGVISVEGRPGLFWFHISDGDKDMDFDIEKTTGSIVIARPLDTRRKSSYNLTVEVTDGFHTIATQVHILMIANINHHRPQFLQDHYDIRVPQDTLPGVELLRVQATDQDHGKGLIYTIHSSRDPGSANLFQLDPSSGVLVTVGTLDLHSGPSQHILTVMVRDQEMPIKRNFVWVTIHVEDGNLHSPHFTQPRYEANVPDTTTPGTELLQVRAVDADRGANAEVHYSFLKGNSEGFFNIDSLLGIITVAQRLDHVHLNRHALTVKAEDQGSPQRHDLAMVVVHVHPSDSSAPIFSKDEYFIEIPESVPIGSPILLISAASSSDVTYELREGNKNSVFSMNSYSGLISTQKRLDHEKVSSYQLKIRGSNMAGVFTEVVALVYIIDENDNAPAFLKSTFVGHISEAAPLHSLILGEDNSP---LVIRASDSDQEANSLLVYKILEPEALKFFKIDPSMGTLTITSELDYETTPLFQFSIYVHDQGTPILFAPRSARVIIHVRDVNDSPPRFSEQIYEVAVVEPIHPGMELLTVQAEDND-SKVTYSIKTSNTDEAVTIHPITGQISVVNPAALR----LFPKLNIRAFDGLYQDTAVVKISLTQALDKSLQFDQDIYRARVTENTPHSNVLVILGVHGNHLNDTLSYFLLNGTDLFHMVKSAGVLQTRGVTFDREQQDTHEVAVEVR-----DNRVPRRVAQALVRVSVEDVNDNIPEFQHLPYYTVIQDGTEPGDVLFQVSATDKDLGANGTVTYGFAEDY-AYFRIDPYVGDISLKKPFDYQALNKYHLRVTARDAGTPPLQTEVEVHVTVRNKSNPLFQSPYYKVKVPENITLYTPILH-TQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKNKHVFTVRATDTALGSFSEATVEVLVEDINDNPPTFSQLVYSTSVSEGSPAQTPVIQLLASDQDSGQNQDVSYQIVED-GSDVSKFFRINGSTGEMFTIQELDYEAHQHFRVKVRATDRGDPPLTGETLVVVNVSDINDNPPEFREPQYEANVSELATCGHLVLKVQALDPDIGDTSRLEYLILSGNQDRHFSINSTSGIISMFNLCKKQLDSSYNLRVGASDGVFQATVPVYINTTNANKYSPEFQQNVYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGERFFINPS-GQITTLQKLDRENSTERVIAIKIMARDGGGKVAFCTVKIILTDENDNAPQFKASGYTVSIPSNVSRDSPIIQVLAYDADEGRNADVTYSVDS--TEDLAEEIIEVNPTTGVVKVKESLVGLENKAVDFNIKAQDGGPPHWDSLVPVRLQVVPNEIPLPKFSEPLYTFSASEDLPEGSEIGSVKAVAAQDPIIYSLVQGTTPESNSDDVFSLDQDTGVLKVKKAMDHESTKWYQIDLMAHCPHEDTDLVSLVSVNIQVEDVNDNRPVFEADPYKAFLTENMPGGTTVIQVTANDQDTGSDGQVSYRLSVEPGSNIHQLFAVDSESGWITTLQELDCETQQTYRFYVVAFDHGQTIQLSSQALVEVSITDENDNPPRFASEDYRGSVVENNEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFSISQVGDEWRITSRKTLDREHIAKYLLRITASDGKFQASVPVEVFVLDINDNSPQCSQLLYTGKVREDVTPGHFILKVSAIDVDMDTNAQITYSLHGPGAQEFKLDPHTGELTTLSVLDRERKDVYNLVAKATDGG--GQSCQAEVTLHIEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGVNAQVVYSLTDSADGQFSIDATSGVIRLEKPLQVRSSSAVELTVRASDLGTPIPLSTLGTVTVSIVGLEDYLPIFLNSEHSTQVPEDALIDMEVLYLATLTRPG--SEKTGYHITGGNEQGKFRLDAHTGILYVNGSLDFETNPKYFLSIECSRKSSSSLSDVTTIVINVTDVNEHHPRFTHDLYTVRVLENAIVGDVILTVSASDDDGPVNSVITYSLVGGNQLGHFTIDPKKGKLQVAKALDWEQTPSYSLRIRATDSGQPPLHEDTEVAVEVVDVNDNPPRFFQLNYSTAVQENSPIGIKVLQLILDDPDSPQNGPPYFFRITEGNTGSVFRVTPDGWLVTAGSLSRRAQEWYQLHIEVSDSGLPPLSSSTLVRVHITEQSRYPPSTLPLEIFITKGEEEFQGGMVGKIHATDRDPQDTLTYSLDREGS----LGKYFTVGASDGKIIASQGLPRGRYLFNVTVSDGTFTTTTGVHVHVWHMGQEAPQQAVWLGFHQLTPEELVSDHWRNLQRFLSNILDIKRANIHLASLQPAEVTAGVDVLLAFEG--------------------HSGTSYDLQELASAIAHSAKEMEHSVGIQMRSALP-VVPCQGPSCQDQTCQETVSLEPRVGPSYSTARLSILTPRHHLGKNCSCNG----------------------------------------------------------------TTWRFSGQSYMRYRPLEAQN-------WQIHFYLKTLQPWALLMFTN-ETASISLKLANGFLHLEYRCPGGFYGNLSSHRPVNDGQWHSMLLEERDTSVHLLVDITDNTSLVIPEECQGLRTE-RHLLLGGLVPSNPSSN----VSLGFEGCLDAVVVNSERLELLGHRKKMAGYLETWALSQCCWPG-------TTCSQNPCLNGGSCSPALGSGYLCRCPPLFSGRNCELGRENCTSAPCQEGGTCVSS-PEGTSCSCPHPYTG------------------------------------DRCEMEARGCSGGHC---------------------------------LITPEIKRGDWGQQEFLVIIVALPLLIIATVGLLLYCRRCKSHKPVAMEDPD---------LLARSIGVDTQASPAIELDPLNAGS------------------------------------------------------------------------CNDLNQLEPSKTSVPNELVT-FGPSSKQRPMVCSVPPRLPPAVVSSHP---GHEPIIKRTWSGEELVYPSGAAVWPPTYSRKEHWEYPHPEAMQGPLPPSPRRHVSPAVMPDPAGLYGGFPFPLELENKRAPLPPRYSNQNLEDLIPPRP--------------------------PSPREHLLAPCLNEYTAISYYHSQFRQGGGGPCLAEGGYKGVSMRLSRAGPSYADCEVNGGPAPGRSQPRAPPNYEGSDMVESDYGSCEEVMF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYQ8-1", "uniprot_id": "FAT2_HUMAN", "id": "Q9NYQ8-1", "name": "Protocadherin Fat 2", "aln": "----------MTIALLGFAIFLLHCATCEKPLEGILSSSA-------------------WHFTHSHYNATIYENSSPKTYVESFEKMGIYLAEP--QWAVRYRIISGDVANVFKTEEYVVGNFCFLRIRTKSSNTALLNREVRDSYTLIIQATE-----KTLELEALTRVVVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFYYAFNTRSEMFAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKISEGNGFGSLAALVVHVEPALRKPPAIASVVVTPPD-SNDGTTYATVLVDANSS--GAEVESVEVVGGDPGKHFKAIKSYARSNEFSLVSVKDINWMEYLHGFNLSLQARSGSGPYFYSQIRGFHLPPSKLSSLKFEKAVYRVQLSEFSPPGSRVVMVRVTPAFP----NLQYVLKPSSENVGFKLNARTGLITTTKLMDFHDRAHYQLHIRTSPGQ-------ASTVVVIDIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSIAGPKALPFSIDPYLGIISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKSIMTMSAIDVDELQNLKYEIVSGNELEYFDLNHFSGVISLKRPFINLTAGQPTSYSLKITASDGKNYASPTTLNITVVKDPHFE--------VPVTCDKTGVLTQFTKTILHFIGLQNQESSDEEFTSLST----YQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNGKLVYVIADGNEEGCFDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFPPGGYQLTISEDTEVGTTIAELTTKDADSEDNGRVRYTLLSPTEKFSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDGAHG--TFRVDLMTGALILERELDFERRAGYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDD-SGLDGELQYFLRAGTGLAAFSINQDTGMIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMGFFMIHPVTGLLS-TAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKLFNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSIEDSD-EEAFSIDLVTGVVSSSSTFTAGEYNILTIKATDSGQPPLSASVRLHIEWIPW-PRPSSIPLAFDETYYSFTVMETDPVN--HMVGVISVEGRPGLFWFNISGGDKDMDFDIEKTTGSIVIARPLDTRRRSNYNLTVEVTDGSRTIATQVHIFMIANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQDKGKSLIYTIHGSQDPGSASLFQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEIPIKRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYSLLKGNSEGFFNINALLGIITLAQKLDQANHAPHTLTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPILLVSAMSPSEVTYELREGNKDGVFSMNSYSGLISTQKKLDHEKISSYQLKIRGSNMAGAFTDVMVVVDIIDENDNAPMFLKSTFVGQISEAAPLYSMIMDKNNNP---FVIHASDSDKEANSLLVYKILEPEALKFFKIDPSMGTLTIVSEMDYESMPSFQFCVYVHDQGSPVLFAPRPAQVIIHVRDVNDSPPRFSEQIYEVAIVGPIHPGMELLMVRASDED-SEVNYSIKTGNADEAVTIHPVTGSISVLNPAFLG----LSRKLTIRASDGLYQDTALVKISLTQVLDKSLQFDQDVYWAAVKENLQDRKALVILGAQGNHLNDTLSYFLLNGTDMFHMVQSAGVLQTRGVAFDREQQDTHELAVEVR-----DNRTPQRVAQGLVRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDY-TYFRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTPSLQSEEEVLVTVRNKSNPLFQSPYYKVRVPENITLYTPILH-TQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTALGSFSEATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVED-GSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSELATCGHLVLKVQAIDPDSRDTSRLEYLILSGNQDRHFFINSSSGIISMFNLCKKHLDSSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQHLYEAELAENAMVGTKVIDLLAIDKDSGPYGTIDYTIINKLASEKFSINPN-GQIATLQKLDRENSTERVIAIKVMARDGGGRVAFCTVKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSVN---PEDLVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKAQDGGPPHWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDLPEGSEIGIVKAVAAQDPVIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMDHESTKLYQIDVMAHCLQN-TDVVSLVSVNIQVGDVNDNRPVFEADPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRGSVVENSEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGISQVGDEWRISSRKTLDREHTAKYLLRVTASDGKFQASVTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTDTNAQITYSLHGPGAHEFKLDPHTGELTTLTALDRERKDVFNLVAKATDGG--GRSCQADITLHVEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPDSAEGHFSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPG--AEKTGYRVVSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKKGELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTPDGWLVTAEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVRVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVGKIHATDRDPQDTLTYSLAEEET----LGRHFSVGAPDGKIIAAQGLPRGHYSFNVTVSDGTFTTTAGVHVYVWHVGQEALQQAMWMGFYQLTPEELVSDHWRNLQRFLSHKLDIKRANIHLASLQPAEAVAGVDVLLVFEG--------------------HSGTFYEFQELASIITHSAKEMEHSVGVQMRSAMP-MVPCQGPTCQGQICHNTVHLDPKVGPTYSTARLSILTPRHHLQRSCSCNG----------------------------------------------------------------TATRFSGQSYVRYRAPAARN-------WHIHFYLKTLQPQAILLFTN-ETASVSLKLASGVPQLEYHCLGGFYGNLSSQRHVNDHEWHSILVEEMDASIRLMVDSMGNTSLVVPENCRGLRPE-RHLLLGGLILLHSSSN----VSQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHS-------DYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGRENCTFAPCLEGGTCILS-PKGASCNCPHPYTG------------------------------------DRCEMEARGCSEGHC---------------------------------LVTPEIQRGDWGQQELLIITVAVAFIIISTVGLLFYCRRCKSHKPVAMEDPD---------LLARSVGVDTQAMPAIELNPLSASS------------------------------------------------------------------------CNNLNQPEPSKASVPNELVT-FGPNSKQRPVVCSVPPRLPPAAVPSHS---DNEPVIKRTWSSEEMVYPGGAMVWPPTYSRNERWEYPHSEVTQGPLPPSAHRHSTPVVMPEPNGLYGGFPFPLEMENKRAPLPPRYSNQNLEDLMPSRP--------------------------PSPRERLVAPCLNEYTAISYYHSQFRQGGGGPCLADGGYKGVGMRLSRAGPSYAVCEVEGAPLAGQGQPRVPPNYEGSDMVESDYGSCEEVMF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW71-1", "uniprot_id": "FAT2_DROME", "id": "Q9VW71-1", "name": "Fat-like cadherin-related tumor suppressor homolog", "aln": "MFTMKIKKYVTPVKRKAFTILQWISLLCSLWLIPTVQSKADEKHTATLEYRLENQLQDLYRFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRVGLNAEVKYRIISGDKEKLFKAEEKLVGDFAFLAIRTR-TNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVNDKDTGINGNIGRLEIVDGNPDGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSIS---CDLKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVN-FPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSP--VLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMS-IVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVN-DQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPS--SATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDDNDQLWYNISNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAFTNLLVQVID-INDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEK-TAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSIFFNIISGNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDADNDTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASDGIFSAILIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRILNPTQLFDIGISSGALKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNGELFKLDRKSGELSIKQHVEGHNR-NYELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAESPLGRSLIYTISSES--QSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSD--GGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGNYTFKFS---------IAADQDHFMISDSGELILQQTLDREQQESHNLIVVAETSTV-PVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDT-ENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADN-GHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQ--EMDFFIVSGDKQAQFQIGKSGELFIAKP---LDREQLMFYNLSIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQS--KLRFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVPK-LHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPLEVTINSFEDDFSGAFIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIGLYKLNVSVSDGKFHVFSIVKINVELVTNDMLKESVVIRFRRISASEFLLSHRKTFMRSIRNIMRCRQKDVILITLQSDYQKASQHAVGNRRARSIDSDLNVVFAVRKQQIIPDSDEFFTSDEIRQTLIDKKNEIENETNLVVEDVLPSTCQSNKNDCVHGECKQILQILKNNVTTTFTDVISFAAPSYIPVNTCVCRPGFDGKHCKETVNACSTDPCSPQRICMPSGSALGYQCVCPKGFSGTYCERKSSKCSNESCDMGLFTAVSFGGKSYAHYKINKVKAKFTLENGFSYSLQIRTVQQTGTLLYASGKVDYNILEIINGAVQYRFDLGSGEGVISVSSINISDGEWHQISLERSLNSAKVMVDNKHVSHGSAPGVNGILNIQSNDIFVGAEVRPHPSIIGYEDIQRGFIGCMANIKIAKESLPLYISGGSTIAALKRFTNVEFKCDPSNVLVRLGICGSQPCANSGICKELDTDVFECACQPRYSGKHCEIDLDPCSSGPCLFGGRCDYHGPNNYSCTCPIHLSGKRCEYGKFCTPNPCKNGGICEEGDGISHCMCRGYTGPTCEIDVDECENQPCGNGATCINEPGSFRCICPSYLTGASCGDPLYSNSISTKLKNFSIEHISGIISGVAVVLVIISCVLCCVVLKRSSSSKRRNRLEKDKNKSSYKEANLNSLVDKDNYCKPNVKLSNLEVNQRPISYTAVPNDNLVLSNRNFVNNLDILRSYGSAGDELENVPFEYQKVNRNKQHVNINSCHSTDADNAYKQEWCEQMHLRTFSENKLNNELKRDFGPSVSRFSTGKLIQVEMPNVCHSSSANFVDYSALANGQYHWDCSDWVRKSHNPLPDITEVPGAEIADSSSLHSNDSNESKSKKAFFVHREDGDVDPTRDIAALNEDIGSEYLDSEAESCLEPFMLPRSSNQPLSRLSSFNNIENEDYKSNTVPLPSKVSHSCKVYLRHPDSYLPTMHFPSETDGESSMTEGPISRMEIKTRRTISENSEEAYLFPCTVGEIGSNSNISVRLCEIEDSELEEFLPQQQTNN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: ..::. *. * : . : ::*:** **.** *** ***.:. : : . : *:******* :**:** :**:*.** ***: :*..:**** :.*.: ::* : . *: :.: :::**:***.*** *..* ..*.** * ..* **** ***** *.*:**:: ** ******:* :*: :*: : ..:.** *:* ** :.. * .. : : : *: . .* * .... .: *. * *: :.: ..:: :*:*.*:*. * : ::.: : : :: * : ::: . . * : :*.*.:.* :* . * ::*: . : : .. . *::*. :*:: *:* :* ..: * * : : ::: * *.: * *:: *:*:. . :::** .*: *: :**.*:* *:*.:::****. :*:**.** *::.*:. :*:* *** * : :****** *:*::.*:.: : ::::***:* **.*** .: :. *:*..::. ****.* : :.*.: .*** *.*: ** :*:. :*. * **::*:**.:::. ::: :: : .. * :*** ::::*: : :. . . *:.*. * * : *:* : ***.:.: *.* :. .:* : *.* * *::*:**:.*:**: :. * *: : * * : . ** * . *:**:******.* **: *:*.:.: * **: * : : ::*.:.:**.: * : *:** * :* *:* ..*:::. ** * :. ****.: .* *: *:* : * * : : : ::*:***.* .:. :** **:* ****:.::* * *:** .*::: * : .:. *::. ***: : **:*.: :** . * *.* * :. : ::::***** ..*.* .**::*:*:**.* ** *: *:*:* * .*:.:: * : .* ** *::* * * : :*: ** * :****: * * . **** .****:* : *** * .:.*:* .: * : ...:: *.*:*** .. .:*:*:.*** :*.* :.. **::. * ::*****: *::***:: ***.* * ****:** :**:***.* *.:::::*::.. *. .:::: * * *.* ** :****:... :: * ** * : :..: :.: : *** *.* * * :.*::* :* *.... ** . :: ... : : : :::*:. . :*::**.*:.* * * : .*.*:::: ** . :..****:.**** * *:: : :* **.: *** : *.:.:.:: :::::* *:*..* *:* : .::**.* **::*. ** ::.. *:: . .:** * *:*:** * ***:. : ::*.* * * *.** ::.**:: : *::* :***:* * * ***::**::.** ..*:*:. :****:* .* : : * *** * *.* . * : * *: ..* *...: :** *.:*:*: : ::* *.*.: ::: .** : * :*. :*:* : .:*:*.: :.* ::*:***. : :: *:* *** * * : ::* :.*:*.: * :: .:.. :.::..*:* .*.:: *:*:: * :*****.: *:: ::*:* . : * : * * *.* *.:. .*:* *:* :***.** *.*: :*::. * . .: : * *.* * . : :.* .*::*.. *. ** *:. * * : :** **:: :***.: ..:*..: *::: * . ** . .: ::.. ** *::.:.* :** *::*.: *:*.*:* * **** :* :.: **.: . . * * : :*: ***** * * ::***: :. . * :::**.* * * . ** * * : :. *::* *::*:*: .: : :*.* * * *.. .. .:* : *.* ::* *:*:. :*.* * *:: :*:.: :*.** * ***.* .*. * *::** : *.. ****. ..* .::****: * ::*..:.* : *:** * :.. :*. ::.*. . * :::: *:*:*** * .:** * . *.: *::* *: : *:: **** ::.:: *.. *:*.*.*:..: *.:.*.*:***.* * :*.* ::** *. *::* :* * * **. *** *: **: : : *:. :*:**: *: : .** *.:..****. * . : *. * *** *:* ***::.** * ::* : * * * *.*..: * *:.: : * *: * *:: .:***:. * *: :*: ***:..*.::*:*:.* *** * * . *.: : :.*. :..:: * * * * *..* :.: :. .:::**:* ** : .*.. . .: :* ::*.* * *::.* *** :::: .. :*.*.:. :. *. * *: : :: :. : * . : *:* : :::.:*:*. : ::: ::*. . ..: ..* *:* * *** * *: *.* ::** ::::*:* * *** :*:: * *. :. .*::::* :* ***** * .** *. . *.* *:* *: : .::. * :.*.* ***.* * **.** ** :: .* :*.*:..* :: :*..** .** *.: *: : .. ****: * * : *:**** *.. **: * *:***:* * : * ...*.: * :::*.* *.* :: :: : * * **.:*.:. .:* *.. :.**** . ::***:. ** :.* ::: : ::*:*** * * :: *:* ::: ::* :: *.* * * *.* *: *** .. .. *.*. ::*:***.*.*: .. : .:***:*.* *.* * ::.**:*.::.::* * * ::* :: *:* . ** : : : . * : .*****:*::*: ** * :*.:**:* . ***:*:. .:..**: : : :.: *:*:: * * :: * .* *: .**. ** *.*:*:*. :*. :**.: *:::*:*:*.**:* :.*::.** * . *:*.::* *.*:* :.. : ::: *.***.* * . ***. :*** :* .* : :.*.*.. * .** * * .** *. **: ** * ** :.:. :: : :::.. *.* *** * : * *:: *:*:*.* . ***: *. *::*.*.::**:**:*:* * *.:** .: *.:. *** * ..* * * :**:****.* . : *:: * : : :::: : * :::..*:: .* :.: * : : : :: :: * :**. *. ..: . .*. : :*: . : .. .*:*:...: :...:* .: * *:: : : . .: * :*: :* : ..* *. *: *.*:** :*: .: : : ::*:* . *:::. :. *:: .* : .: .* * :.* :**.: :*. * :::** : * *. : ..:::*. : :.* :. ** **: : : * * * . . *: : : *....* *.* *. : * * * :**::** . : *: .** ** * *:. **.** :* **::. *. * ::.:::. . : . :: **: ::**: * . :* .* * : * * :. *. . * ::*. *.... *:::: *: .: *** ***. .: . : .:* . .* . . ..: : : : : : * :. * .... :. . ..: : * : .: :. *: : ::. ** :: .*. ** .: *.. : : .* ..:::* . : :: *: .. : *. .. . . .:: :*: . ", "identical_positions": 1260, "similar_positions": 1570, "identity": "26.6%" }, { "cls_id": "homologset.agr.RGD:620657", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R508-1", "uniprot_id": "FAT3_RAT", "id": "Q8R508-1", "name": "Protocadherin Fat 3", "aln": "-MGVTMRHCIDTRPPS-CLIFLLLKLCA------------------TVSQGLPGTGPLGFHFTHALYNATVYENSAARTYVN--SQSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIIKGSVRGED-----LEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPIIHVVTHTPFSLDKEP-TYAVVTVDDLDEGANGEIESVSIVDGDPLEQFFLAKEGKWMNEYKVKERRQVDWESFSYGYNLTIQAKDKGSPQKFSELKTVHIANPRRDSTPIKFEKDVYDISISEFSPPGVMVAIVKVNPEPLD----VEYKLLPGKDAEYFKINPRSGLIVTAQPLNTVKKEVYKLEVSDKEGD-------AKAQVTIGIEDANDHTPEFQETLYETFVNESVPVGTNVLTVSASDKDKGENGYITYSIASLNLLPFAINQFTGVISTTEELDFESSPETYRFIVRASDWGSPYRHESEVNVTIRVGNVNDNSPLFEKVACQGVISYDFPVGGHITAISAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLMNSGIKNGNFALRITATDGENFADPMAINISVLHGKVSSKS--------FSCRETRVAQKLAEKLLIKAKANGKLNQEDGFLDF------YSINRQGPHFDKSFPSDVAVKENMPVGTNILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYVLNITIYDLGKPQKSSWRLLTVNVEDANDNSPVFLQDSYSVSILESSSIGTEIIQVEARDKDLGSNGEVTYSVLTDTHQFVINSSTGIVYIADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKIFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETQDPDLGLGGQVRYSLVNDYNGR--FEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSISFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTAHDED-SGRDGEIQYSIRDGSGLGRFNIDDESGVITAADILDRETTASYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSGSNEKLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGSSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKTGMVSSRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSP-IPLTFDEPFYNFTIMESDKVT--EIVGVVSVQPANTPLWFDIIGGNFDSSFDAEKGVGTIVIAKPLDAEQRSVYNMSVEVTDGTNVAVTQVFITVLDNNDNGPEFSQPHYDVTISEDVPPDTEILQIEATDRDEKHKLSYTIHSSIDAISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSVVLQVTALDKDKGENAELIYSIEAGNTGNTFKIEPVLGIITISKEPDMTAMGQFVLSVKVTDQGSPPMSATAIVRISISMSDNSHPKFTHKDYQAEVNENVDIGTSVILISAISQSTLIYEVKDGNINGVFTINPYSGVITTRRALDYEHTSSYQLIIQATNMAGMASNATVSVQVVDENDNPPVFLFSQYSGSLSEAAPINSLVRSLDNSP---LVIRATDADSNQNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHEVIAHFHFHVHVRDSGNPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETVLLLPTYVGVEVLKVSATDPDSEVPPELTYSLMEG-SVDHFLMDPNTGVLTIKN----NNLSKDHYMLIVRVSDGKFYSTAMVTIMVKEAMDSGLHFTQSFYSTSISENSTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDH-----LRVARVVVRVNIEDVNDNSPVFVGLPYYAAVQVDAEPGTLIYRVTAIDKDKGANGEVTYVLQDDYG-HFEINPNSGNVILKEAFNSDLSNIDYGVTILAKDGGTPSLSTFVELPITIVNKAMPVFDKPFYTASINEDISIN-TPILSINATSPEGQGIIYLIIDGDPFQQFNIDFDTGVLKVISPLDYEVMSVYKLTVRASDALTGARAEVTVDLLVDDVNDNPPVFDQPTYNTTLSESSLIGTPVLQLVSTDADS-GNNNLVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVTATDNGFPSLSSEVLVQIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVLTLSSHRKQRMEPLYSLNVSVSDGLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENAASGTKVIHVRATDGDPGTYGQVSYSIINDFAKDRFLIDSNGQIITTER-LDRENPLEGDISIYLRALDGGGRTTFCTVRVIVVDENDNAPQFMTLEYRASVRADVGRGHLVTQVQALDPDDGANSRITYSLYSEAS-VSVADLLEIDPDNGWMVTKGNFNQLRNTVLSFFVKAVDGGIPVRHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTSIGSTIDTLRILPNQSVRFSTVNGERPENNKENVFIIEQETGAIKLDKRLDHEVSPAFHFKVAATIPLDKVDIVFTVDVDVKVLDLNDNKPVFETSSYETIIMEGMPVGTKLAQVRAIDTDWGANGQVTYSLHSDSHLEKVMEAFNIDSNTGWISTLKDLDHETDPTFSFFVVASDLGEAFSLSSMALVSVKVTDINDNAPVFAHEVYRGNVKESDPPGEVVAVLSTLDKDTSNINRQVSYHITGGNPRGRFALGMVQSEWKVYVKRPLDREEQDIYFLNITASDGLFVTQAMVEVTVSDVNDNSPVCDQVAYSASLPEDIPSNKIILKVSAKDADIGSNGDIRYSLYGSGNSDFFLDPESGELKTLALLDRERVPVYNLIARATDGG--GRFCSSTVLLLLEDVNDNPPVFSSNHYTACVYENTATKALLTRVQAVDPDVGINRKVVYSLEDSASGVFSIDSSSGVIVLEQPLDREQQSSYNISVRATDQSPGQSLSSLTSVTITVLDINDNPPVFERRDYLVTVPEDTSLGTQVLSVFATSKDIGTNAEITYLIRSGNEQGKFRINPKTGGISVLEALDYEMCKRFYLVVEAKDGGTPALSTAATVSIDLTDVNDNPPRFSQDVYSAVISEDALEGDSVILLIAEDVDSKPNGQIRFSIVGGDRDNEFAVDPILGLVKVKKKLDRERVSGYSLLIQAVDSGIPAMSSTTTVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEDEEFMLDSHGILRSAVVFRHMESPEYLLCIQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTFALKS------EQKSLFKVNSHDGKIIALGGLDSGKYVLNVSVSDGRFQVPIDVVVHVEQLVHEMLQNTVTIRFENVSPEDFVGLHMHGFRRILRNAVLTQKQDSLRIIS-------IQPVVG-------TNQLDMLFAVEMH-----SSEFYKPAYLIQKLSNARRHLEN--VMHIAAILEKNCSG--LDCQEQHCEQGLSLDSHALMTYSTARISFVCPRFYRNVRCTCN----GGVCPGSNDPCVEKPCPEDMQCVGYEASRRPFLCQCPPGKLG--------ECSG-------HTSLSFAGNSYIKYRLSEN----SREEDFKLALRLRTLQSNGIIMYTR-ANPCMILKIVEGKLWFQLDCGSGPGILGISSRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQTLSTDS-AIFFGALVQADNIRSLTDTRVTQVLGGFQGCLDSVVLNHNELPLQNKR-SSFAEVVGLTELKLGC-----VLYPDACQRSPCLHGGSCSGLPSGGYQCSCLSQFTGTNCESEITACFPNPCRNGGSCDPIG-NTFICSCKAGLTG------------------------------------VTCEDDVDECEREECENGGSCVNLFGSFFCNCTPGYVGQYCGLRPVVVPNIQAGHSYVGKEELIGIAVVLFVIFTLIVLFIVFRKKVFRKNYSRNNITLVQDPATAALLHKSNGIPFRSLR-AGDGRNVYQEVGPPQVPVRPMAYTPCFQSD---SRSNLDKGLDAL---GGEPQELSTFHPESPRILTARRGVVVCSVAPNLPAVSPCRSDCDSIRKNGWDTGSENKGAE-DTGEVTCFANSNKGSNSEVQSLNSFQSD------SGDDNAYHWDTSDWMPGAR--LSDIEEMPNYESQDGGAVHQGSTRELESDYYLGGYDIDSEYPPPHEEEFLSQDQLPPPLPEDFPEQYE--ALPPSQPTSLTGTMSPDCRRRPRFHPSQYLPPHPLPGETDLGGPPSSCDFSTFAVSMNQGTEVMAPTDSVSLSLHNSRGTSS--SDMSARCGFDDSEVAMSDYESAGELSLTNLHIPFVETQHQTQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BNA6-1", "uniprot_id": "FAT3_MOUSE", "id": "Q8BNA6-1", "name": "Protocadherin Fat 3", "aln": "-MSVTMGHCMGTKPPS-CIILLLLKLFA------------------TVSQGLPGTGPLGFHFTHSTYNATVYENSAARTYVN--SQSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIIKGSVRGED-----LEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPIIHVVSHTPFSLDKEP-TYAVVTVDDLDEGANGEIESLSIVDGDPLEQFFLAKEGKWLNEYKVKERRQVDWESFSYGYNLTIQAKDKGSPQKFSELKTVHIANPRRDNTPVRFEKDVYEVSISEFSPPGVLVAIVKVSPEPLD----VEYKLLPGKDSDYFKINPRSGLIVTAQPLNTVKKEVYKLEVSDKEGD-------AKAQVTIGIEDANDHTPEFQEALYETFVNESVRVGTNVLTVSASDKDKGENGYITYSIASLNLLPFAINQFTGVISTTEELDFESSPETYRFIVRASDWGSPYRHESEVNVTIRVGNVNDNSPLFEKVACQGVISYDFPVGGHITAISAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLMNSGIKNGNFALRITATDGENFADPMAINISVLHGKVSSKS--------FSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDF------YSINRQGPHFDKSFPSDVAVKEDMLVGTNILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYVLNITIYDLGKPQKSSWRLLTVNVEDANDNNPVFLQDSYSVSILESSSIGTEIIQVEARDKDLGSNGEVMYSVLTDTHQFIINSSTGIVYIADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKIFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETQDPDLGLGGQVRYSLVNDYNGR--FEVDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTAHDED-SGRDGEIQYSIRDGSGLGRFNIDDESGVITAADSLDRETTASYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSGSNEKLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGSSPKQSTIWVVVQVLDENDNRPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDKDEGPNAEISYSIVDGNDDGKFFIDPKTGMVSSRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSP-IPLTFDEPFYNFTVMESDKVT--EIVGVVSVQPANTPLWFDIVGGNFDSSFDAEKGVGTIVIAKPLDAEQRSVYNMSVEVTDGTNIAVTQVFIKVLDNNDNGPEFSQPHYDVTISEDVLPDTEILQIEATDRDEKHKLSYTIHSSIDAVSMRKFRMDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSVVLQVTALDKDKGENAELIYSIEAGNTGNTFKIEPVLGIITISKEPDMAAMGQFVLSVKVTDQGSPPMSATAIVRISISMSDNSHPKFTHKDYQAEVNENVDIGTSVILISAISQSTLIYEVKDGNINGVFTINPYSGVITTRRALDYEHTSSYQLIIQATNMAGMASNATISVQIVDENDNPPVFLFSQYSGSLSEAAPINSIVRSLDNSP---LVIRATDADSNQNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHEAIAHFHFHVHVRDSGNPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETVLLLPTYIGVEVLKVSATDPDSEVPPELTYSLMEG-SVDNFLMDPNTGVLTIKN----NNLSKDHYMLIVRVSDGKFYSTAMVTVMVKEAMDSGLHFTQSFYSTSISENSTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDH-----LRVARVVVRVNIEDVNDNSPVFVGLPYYAAVQVDAEPGTLIYRVTAIDKDKGANGEVTYVLQDDYG-HFEINPNSGNVILREAFNSDLSNIDYGVTILAKDGGNPSLSTFVELPITIVNKAMPVFDKPFYTASINEDITMN-TPILSINATSPEGQGIIYLIIDGDPFQQFNIDFDTGVLKVISPLDYEVTSVYKLTVRASDALTGARAEVTVDLLVDDINDNPPVFDQPTYNTTLSESSLIGTPVLQLVSTDADS-GNNKLVRYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVTATDNGFPSLSSEVLVQIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDLDRLEYSILSGNDRASFLMDSKSGVLTLSSHRKQRMEPLYSLNVSVSDGLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENAASGTKVIHVRATDGDPGTYGQVSYSIINDFAKDRFLIDSNGQIITTER-LDRENPLEGDISIYLRALDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGRGHLVTQVQALDPDDGANSRITYSLYSEAS-VSVADLLEIDPDNGWMVTKGNFNQLRNTVLSFFVKAVDGGIPVRHSLIPVYIHVLPPETFLPSFTQSQYSFTITEDTSIGSTVDTLRILPNQSVRFSMVNGERPENNKEGVFIIEQETGAIKLDKRLDHEVSPAFHFKVAATIPLDKVDIVFTVDVDVKVLDLNDNKPVFETSTYETIIMEGMPVGTKLAQVRAIDMDWGANGQVTYSLHSDSHLEKVIEAFNIDSNTGWISTLKDLDHETDPAFSFFVVASDLGEAFSLSSMALVSVKVTDINDNAPVFAHEVYRGNVKESDPPGEVVAVLSTLDKDTSNINRQVSYHITGGNPRGQFALGMVQSEWKVYVKRPLDREEQDIYFLNITASDGLFVTQAMVEVTVSDVNDNSPVCDQVAYSASLPEDIPSNKIILKVSAKDADIGSNGDIRYSLYGSGNNEFFLDPESGELKTLAVLDRERVPVYNLIARATDGG--GRFCSSSVLLLLEDVNDNPPVFSSNHYTACVYENTATKALLTRVQAMDPDVGINRKVVYSLEDSASGVFSIDSSSGVIVLEQPLDREQQSSYNISVRATDQSPGQSLSSLASVTITVLDINDNPPVFERRDYLVTVPEDTSLGTQVLSVFATSKDIGTNAEITYLIRSGNEQGKFSINPKTGGISVLEALDYETCRRFYLVVEAKDGGTPALSTAATVSIDLTDVNDNPPRFSQDVYSAVISEDALEGDSVILLIAEDVDSKPNGQIRFSIVGGDRDNEFAVDPILGLVKVKKKLDRERVSGYSLLIQAVDSGIPAMSSTTTVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEDEEFMLDSHGILRSAVVFRHMESPEYLLCIQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTFALKS------EQKSLFKVNSHDGKIIALGGLDSGKYVLNVSVSDGRFQVPIDVVVHVEQLVHEMLQNTVTIRFEDVSPEDFVGLHMHGFRRILRNAVLTQKQDSLRIIS-------IQPVVG-------TNQLDMLFAVEMH-----SSEFYKPAYLIQKLSNARRHLEN--VMHIAAILEKNCSG--LDCQEQHCEQGLSLDSHALMTYSTARISFVCPRFYRNVRCTCN----GGVCPGSNDPCVEKPCPEDMQCVGYEASRRPFLCQCPPGKLG--------ECSG-------HTSLSFAGNSYIKYRLSEN----SKEEDFKLALRLRTLQSNGIIMYTR-ANPCMILKIVEGKLWFQLDCGSGPGILGISSRAVNDGSWHSVFLELNRNFTSLALDDSYVERRRAPLYFQTLSTDS-AIFFGALVQADNVRSLTDTRVTQVLGGFQGCLDSVVLNHYELPLQNKR-SSFAEVVGLTELKLGC-----VLYPDACQRSPCLHGGSCSSLPSGGYQCSCLSQFTGTNCESEITACFPNPCRNGGSCDPIG-NTFVCSCKAGLTG------------------------------------VTCEDDVDECEREECENGGSCVNLFGSFFCNCTPGYVGQYCGLRPVVVPNIQAGHSYVGKEELIGIAVVLFVIFTLIVLFIVFRKKVFRKNYSRNNITLVQDPATAALLHKSNGIPFRSLR-AGDGRNVYQEVGPPQVPVRPMAYTPCFQSD---SRSNLDKGLDVL---GGEPQEMSTFHPESPRILTARRGVVVCSVAPNLPAVSPCRSDCDSIRKNGWDTGSENKGTE-DTGEVTCFTNSNKGSNSEVQSLSSFQSD------SGDDNAYHWDTSDWMPGAR--LSDIEEMPNYESQDGGAAHQGSTRELESDYYLGGYDIDSEYPPPHEEEFLSRDQLPPPLPEDFPDQYE--ALPPSQPTSLTSTMSPDCRRRPRFHPSQYLPPHPLPGETDLGGPSSSCDFSTFAVNMNQGTEVMAPTDSVSLSLHNSRGTSS--SEMSARCGFDDSEVAMSDYESAGELSLTNLHIPFVETQQQTQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDW7-3", "uniprot_id": "FAT3_HUMAN", "id": "Q8TDW7-3", "name": "Protocadherin Fat 3", "aln": "-MDIIMGHCVGTRPPACCLILLLFKLLA------------------TVSQGLPGTGPLGFHFTHSIYNATVYENSAARTYVN--SQSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIVKGSVRGED-----LEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTIHVVTHVPFSLEKEP-TYAVVTVDDLDDGANGEIESVSIVAGDPLDQFFLAKEGKWLNEYKIKERKQIDWESFPYGYNLTLQAKDKGSPQKCSALKAVYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKLSPEPID----VEYKLSPGEDAVYFKINPRSGLIVTARPLNTVKKEVYKLEVTNKEGD-------LKAQVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIASLNLLPFVINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIRIGNVNDNSPLFEKVACQGVISYDFPVGGHITAVSAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLTNSGIKNGNFALRITATDGENLADPMSINISVLHGKVSSKS--------FSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDF------YSINRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQDSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLTDTQQFAINSSTGIVYVADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDYNGR--FEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDED-SGRDGEIQYSIRDGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKTGMVSSRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSP-IPLTFDEPFYNFTVMESDRVT--EIVGVVSVQPANTPLWFDIVGGNFDSAFDAEKGVGTIVIAKPLDAEQRSIYNMSVEVTDGTNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQIEATDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITICKEPDMTTMGQFVLSIKVTDQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISAISQSTLIYEVKDGDINGIFTINPYSGVITTQKALDYERTSSYQLIIQATNMAGMASNATVNIQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSP---LVIRATDADSNRNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETILLLPTYVGVEVLKVSATDPDSEVPPELTYSLMEG-SLDHFLIDSNSGVLTIKN----NNLSKDHYMLIVKVSDGKFYSTSMVTIMVKEAMDSGLHFTQSFYSTSISENNTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDH-----LRVARVVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQDDYG-HFEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKPSLSTSVELPITIVNKAMPVFDKPFYTASVNEDIRMN-TPILSINATSPEGQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTIRASDALTGARAEVTVDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDADS-ENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVITLSNHRKQRMEPLYSLNVSVSDGLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDRFLIDSNGQVITTER-LDRENPLEGDVSIFVRALDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGRGHLVTQVQAIDPDDGANSRITYSLYSEAS-VSVADLLEIDPDNGWMVTKGNFNQLKNTVLSFFVKAVDGGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTAIGSTVDTLRILPSQNVWFSTVNGERPENNKGGIFVIEQETGTIKLDKRLDRETSPAFHFKVAATIPLDKVDIVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHSDSQPEKVMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVASDLGEAFSLSSTALVSVRVTDINDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITATDGLFVTQAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSNGYIRYSLYGSGNSEFFLDPESGELKTLALLDRERIPVYSLMAKATDGG--GRFCQSNIHLILEDVNDNPPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSLADSAGGVFSIDSSSGIIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRDYLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLDYELCKRFYLVVEAKDGGTPALSAVATVNINLTDVNDNPPKFSQDVYSAVISEDALVGDSVILLIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVKVKKKLDRERVSGYSLLVQAVDSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEEEEFVLDPHGILRSAVVFQHTESLEYVLCVQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTFALKS------EQKSLFKVNSHDGKIIALGGLDSGKYVLNVSVSDGRFQVPIDVVVHVEQLVHEMLQNTVTIRFENVSPEDFVGLHMHGFRRTLRNAVLTQKQDSLRIIS-------IQPVAG-------TNQLDMLFAVEMH-----SSEFYKPAYLIQKLSNARRHLEN--IMRISAILEKNCSG--LDCQEQHCEQGLSLDSHALMTYSTARISFVCPRFYRNVRCTCN----GGLCPGSNDPCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLG--------ECSG-------HTSLSFAGNSYIKYRLSEN----SKEEDFKLALRLRTLQSNGIIMYTR-ANPCIILKIVDGKLWFQLDCGSGPGILGISGRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQTLSTES-SIYFGALVQADNIRSLTDTRVTQVLSGFQGCLDSVILNNNELPLQNKR-SSFAEVVGLTELKLGC-----VLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDPIG-NTFICNCKAGLTG------------------------------------VTCEEDINECEREECENGGSCVNVFGSFLCNCTPGYVGQYCGLRPVVVPNIQAGHSYVGKEELIGIAVVLFVIFILVVLFIVFRKKVFRKNYSRNNITLVQDPATAALLNKSNGIPFRNLRGSGDGRNVYQEVGPPQVPVRPMAYTPCFQSD---SRSNLDKIVDGL---GGEHQEMTTFHPESPRILTARRGVVVCSVAPNLPAVSPCRSDCDSIRKNGWDAGTENKGVD-DPGEVTCFAGSNKGSNSEVQSLSSFQSD------SGDDNAYHWDTSDWMPGAR--LSDIEEVPNYENQDGGSAHQGSTRELESDYYLGGYDIDSEYPPPHEEEFLSQDQLPPPLPEDFPDQYE--ALPPSQPVSLASTLSPDCRRRPQFHPSQYLPPHPFPNETDLVGPPASCEFSTFAVSMNQGTEPTGPADSVSLSLHNSRGTSS--SDVSANCGFDDSEVAMSDYESVGELSLASLHIPFVETQHQTQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW71-1", "uniprot_id": "FAT2_DROME", "id": "Q9VW71-1", "name": "Fat-like cadherin-related tumor suppressor homolog", "aln": "MFTMKIKKYVTPVKRKAFTILQWISLLCSLWLIPTVQSKADEKHTATLEYRLENQLQDLYRFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRVGLNAEVKYRIISGDKEKLFKAEEKLVGDFAFLAIRTR-TNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVNDKDTGINGNIGRLEIVDGNP-DGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPI-FTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNR--ILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVN-FPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSP--VLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDP-SLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQ-GSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVN--QSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDDNDQLWYNISNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSIFFNIISGNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDADNDT---LRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASDGIFSAILIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRILNPTQLFDIGISSGALKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNGELFKLDRKSGELSIKQHVEG--HNRNYELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAESPLGRSLIYTISSES--QSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREK--KDEYVVLLKVSDGGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGNYTFKFSIAADQD--------HFMISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFAY-ADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDT--ENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHP-KHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIE--KQEMDFFIVSGDKQAQFQIGKSG---ELFIAKPLDREQLMFYNLSIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQS--KLRFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCG-VPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPLEVTINSFEDDFSGAFIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIGLYKLNVSVSDGKFHVFSIVKINVELVTNDMLKESVVIRFRRISASEFLLSHRKTFMRSIRNIMRCRQKDVILITLQSDYQKASQHAVGNRRARSIDSDLNVVFAVRKQQIIPDSDEFFTSDEIRQTLIDKKNEIENETNLVVEDVLPSTCQSNKNDCVHGECKQILQILKNNVTTTFTDVISFAAPSYIPVNTCVCRPGFDGKHCKETVNACSTDPCSPQRICMPSGSALG-YQCVCPKGFSGTYCERKSSKCSNESCDMGLFTAVSFGGKSYAHYKINKVKAKFTLENGFSYSLQIRTVQQTGTLLYASGKVDYNILEIINGAVQYRFDLGSGEGVISVSSINISDGEWHQISLERSLNSAKVMVDNKHVSHGSAPGVNGILNIQSNDIFVGAEVRPH----PSIIGYEDIQRGFIGCMANIKIAKESLPLYISGGSTIAALKRFTNVEFKCDPSNVLVRLGICGSQPCANSGICKELDTDVFECACQPRYSGKHCEIDLDPCSSGPCLFGGRCDYHGPNNYSCTCPIHLSGKRCEYGKFCTPNPCKNGGICEEGDGISHCMCRGYTGPTCEIDVDECENQPCGNGATCINEPGSFRCICPSYLTGASCG-DPLYSNSISTKLKNFSIEHISGIISG--VAVVLVIISCVLCCVVLKRSSSSKRRNRLEKDKNKSSYKEAN---LNSLVDKDNYCKPNVKLSNLEVNQRPISYTAVPNDNLVLSNRNFVNNLDILRSYGSAGDELENVPFEYQKVNRNKQHVNINSCHSTDADNAYKQEWCEQMHLRTFSENKLNNELKRDFGPSVSRFSTGKLIQVEMPNVCHSSSANFVDYSALANGQYHWDCSDWVRKSHNPLPDITEVPGAEIADSSSLHSNDSNESKSKKAFFVHREDGDVDPTRDIAALNEDIGSEYLDSEAESCLEPFMLPRSSNQPLSRLSSFNNIENEDYKSNTVPLPSKVSHSCKVYLRHPDSYLPTMHFPSETDGESSMTEGPISRMEIKTRRTISENSEEAYLFPCTVGEIGSNSNISVRLCEIEDSELEEFLPQQQTNN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : . *: :.* . *:. * . ::*:*: **.*: *** .:**.: :.*:. :.*. ::****:***:* :***** ::.**.** ***: *..:**** ::*:: :*. *: .* *: ::::*:*** *** *** ** *:*.*.*.** *: :*** ***:* ***:** : . : *::***:* *:* :*:* *:.:::* ::* *** : :* :*.:*: : ::::* :** *.. :. ..: .:* *.:* *:* * * **:* :.** *:* : ** * .: :** :: .: . :. : ****: *:* *:*:: : .. :* .. *: * :::*::**.* :* .: * :*:. :. * :: *::. *:*** **:: **: *:: **. *.* *: : .*:*.*.::* **: * *:: :**. .*: *:.::*.*:*.***.**:****.** :** *::*:*::.**. ****: . *.:*:****** ***:::*::::* : ::*** * **:* * * :: . *:* .: . ****:* :::.*:: .*** * * *:* ** *.:. .* :: :.* *:::**** :::* : **: :: .:...* *.**** **::***.* : * * * . * *: *. * : * * : **.:::::*.: :* .: *:* * * *:***::*:****: ** *.** : *:*::: :***: : *:****:****:* **: ::*.:.: *.*** **: : :. : **: *** : :.* * * * *.:* *:: .: :* :*::** : : . ****.: **:*:* *:* ... * * . : :::***** :*.* ..* .** **** ***:* :*: * *:* ..::::** :: :.. *.:** :**** . ****::*.:** * * * * * **:* : : ::***** .:* * **. *.****. ** *::***:* * . :.:* *** .*.*** * ::*: * **: . ** ** ****: * * .:*** . :****:**: *** ***.:*:** * * * ::*.:* ::* *** ...:.:**.*.*** .:* *: ***:*.**.******:****:***:::*.*.. .** :**.*** *** *:* ::**::::*. : :.*::..*:* *.* *..*:*** .*:...** **.: * : * : :.. : *** *** *:**.***::* : * * ** . :. *.. : .: . :. :::*: * **::* .** *.:* :. *.*:::* ** * :. **:::.***** *.*:::: *:* *** *:*:: *.*.***:: :: *:*:.******.:** * :*:: *. *: **:*. :* : .::***.* :*** ::*:** * :** *::****.* *** * ** : ::.* ****:** : :* *:*:*.*.***: *:* :**.*. *:*:*.:****:. : :: : :::*.:*..* *.**:*: *:* ::**:*. *** :: *: **: *** * ::* *.*:::::: .*:** * *** :***. . :*** . ::* ::.****. :* .: ::::* *** * *: .:* *:*.*:*.*.* * .:.:*. *.::..*** . *.:: *:**:. **:**.:**:****. : :**:*. * : *.* * * *.*:* : :...*.*.* :*** ****.: ::. *:***: .* * :***.*.*.:. * :.:::* : : * :: :*::* :* ** .. .* * *:.*** * : :*.: * .*:**.: * :. * * **.*:::.:.:**.:** *:* ::* **** : *.* :**.::**** **** ::**.*.***. * . :* * . : :.: *:***.*:**.:****:*.:* **:* :*.*** *.. **** * *:.. * *::: :**:: ::: .:. * :* :*: * **. .. *: . * :.:::::****:* ***.*::**: : : :**:* ** *:.:** * . . :.*:**::** : *:. **** * :.:::**:*:*:*. ***.:.: : *:** * ::. ** *:.* : :** :*:: : * ** * :: * : *.:: *:** :.* : **:* ::: : * * * *****. * * :.*:***.* * : * : ** * **:**: :* * * ** * ***.*: **: :: :*. :**::*.. : :. **:*****:.*: *:::* :* *:*** *.**** *:* ** * ::* *:*:*** ***.:: * *:.: *. ****.. :**:: :***: :.: : ::. ****: *.:::***** ***.* *: **: * : * .: : *:* * * *. : :.: .::. :* *::**: ..* :* *.: :. . .***:* * * * ** :** *.:: .:: :*:* :*. :.* *.*. *:.: .*::: . .. ** . .: ..: .::* : *:: **:* . :.:: *.* . * :.: .** :.* * *** * *:.: *.: : *. .*.:* * * * *.**:: * *.**: *:: : *:** :***: *..**:*.:. :.* *:*:* *.. . .: . *::::.* ******* : .* *. ** *: * * * . ::::.:.*..*: :.:* :* :::: :*****: :* *.* *:** *.::* **: *.*:***:* * : * *.*. .. :::*.* * *: * :*: * *.* .:* :. *** **. : **** * *.*:*:. ** : * * : : ::*:*** *:** :* ..* *:: ::*:*:*:*:* *.*:**:: *** .. . *.*..*:*:* *.:.**** * :*::*:* * . .* *:::*::.:******** *. *:* .: *::: **:* *:*** ***.**:* *:* ******** ::..**.: : .**** .: ::*.::* *****.** * *.*.: *:***.* * *::* :.** : *..:: : * * **. ** : :.* **. .:*::** * :.*.: **** :* *:* :** *.* * ..:..:**:* *.***:*:*:.:**:.*:***: :* :* : ::* *. * .*::*.* **** * *: .* **:* *.* . *::: ::. *.*.* *.::: *::**** : * . ***: * ::****.*..***:**:*** ** *.*:* * :...**::..: *** *:..** * * ********:*:* * ::** :.::**:::*.***. :*..:*: * : * * :** : :::* : * * ..* .:*:::***. : *.**:.. : *.* : :..:** : : :* ..*.. ** . .*:* *.: .: : * * ***..* : *.*. * * : :.* .**. : *: :: : * ** * * :**. .*::**.*:** :*::.: : *:.*. :*::**:*..* ::*: **:*::* : :::* *** *::.:*. :.**.**.: ** . * :.: :*:.:*.: ** *. :* *:.** *:.. : :: ** **: .: : : .*** . *::* : :*:::: * :: . * .** :.* *. * :. ::*:* .:::* :** :: .* ..** ** ** * *.: *.* *:* *** *::***.: * **.:*:* *** * *.. .* ** *: .*.: . .. *.: ** * . *::: *: *:::. * :. . ::. . : :::* :..* .: : ::. :* **::**. :.: *. *: : :* * *. :*: .. * :: :: * : * .. . : :. *:.:: . :. .. *: . * * .. .:.* : *: .: .* : :. **** ***: :: *.** *:*. * *..: *...:.* :*. : : *.: *.:: *..* . * .: . * ** *. .*: * : .. ::.. * .. . .: ... :.*: . : . * . ..:* ::* * * *: : .*:. .. *. .: . .: . .*:**: ", "identical_positions": 1614, "similar_positions": 1610, "identity": "33.97%" }, { "cls_id": "homologset.agr.RGD:620658", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15369-1", "uniprot_id": "ELOC_HUMAN", "id": "Q15369-1", "name": "Elongin-C", "aln": "MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYTNSS---TEIPEFPIAPEIALELLMAANFLDC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83941-1", "uniprot_id": "ELOC_RAT", "id": "P83941-1", "name": "Elongin-C", "aln": "MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYTNSS---TEIPEFPIAPEIALELLMAANFLDC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83940-1", "uniprot_id": "ELOC_MOUSE", "id": "P83940-1", "name": "Elongin-C", "aln": "MDGEEKTYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLSKVCMYFTYKVRYTNSS---TEIPEFPIAPEIALELLMAANFLDC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03071-1", "uniprot_id": "ELOC_YEAST", "id": "Q03071-1", "name": "Elongin-C", "aln": "MSQD-------------FVTLVSKDDKEYEISRSAAMISPTLKAMIEGP--FRESKG-RIELKQFDSHILEKAVEYLNYNLKYSGVSEDDDEIPEFEIPTEMSLELLLAADYLSI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : :*.*:*.*.:*: :.*. *: * *:***:.** * *.: .:::::: **:*.*. *:.*:::*:. * ***** *..*::****:**::*. ", "identical_positions": 39, "similar_positions": 43, "identity": "33.91%" }, { "cls_id": "homologset.agr.RGD:620659", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPT8-1", "uniprot_id": "CLIC5_RAT", "id": "Q9EPT8-1", "name": "Chloride intracellular channel protein 5", "aln": "-------------------------------------------------------------------MTDSATANGDDR--------------------------------------------------------------------------------------------DPEIELFVKAG-IDGESIGNCPFSQR----LFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAARHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALRKLDDYLNTPLPEEIDTNTHGDEKGSQRKFLDGDELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVARRLSRS-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BXK9-1", "uniprot_id": "CLIC5_MOUSE", "id": "Q8BXK9-1", "name": "Chloride intracellular channel protein 5", "aln": "-------------------------------------------------------------------MTDSATTNGDDR--------------------------------------------------------------------------------------------DPEIELFVKAG-IDGESIGNCPFSQR----LFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALRKLDDYLNSPLPEEIDTNTHGDEKGSQRKFLDGDELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVARRLSRS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZA1-1", "uniprot_id": "CLIC5_HUMAN", "id": "Q9NZA1-1", "name": "Chloride intracellular channel protein 5", "aln": "MNDEDYSTIYDTIQNERTYEVPDQPEENESPHYDDVHEYLRPENDLYATQLNTHEYDFVSVYTIKGEETSLASVQSEDRGYLLPDEIYSELQEAHPGEPQEDRGISMEGLYSSTQDQQLCAAELQENGSVMKEDLPSPSSFTIQHSKAFSTTKYSCYSDAEGLEEKEGAHMNPEIYLFVKAG-IDGESIGNCPFSQR----LFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVAKRLSRS-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VY78-1", "uniprot_id": "CLIC_DROME", "id": "Q9VY78-1", "name": "Chloride intracellular channel Clic", "aln": "--------------------------------------------------------------MSEVESQQSQETNGSSK------------------------------------------------------------------------------------------FDVPEIELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFEATHPPILIDNGLAILENEKIERHIMKNIPGGYN--LFVQDKEVATLIENLYVKLKLMLVKKDEAKNNALLS----HLRKINDHLS----------------ARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQSCPADQDIINHYKLQQSLKMKKHEELETPTFTTYIPIDISE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:...: *** *::**. ***. * * *.*. *::: ** : ::*****::: *.*::. .****:* ** . : :***..: :.:. * .:.:* * ::: *:. : :..: :* ** *:*::*:*. . . :** ** : **:*:*:*: :::..* : :::**:.:*.****: : * * **::*.**.:* * :. ", "identical_positions": 70, "similar_positions": 88, "identity": "16.13%" }, { "cls_id": "homologset.agr.RGD:62066", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTY3-1", "uniprot_id": "A0A0G2JTY3_RAT", "id": "A0A0G2JTY3-1", "name": "", "aln": "MAITALSYSQPCSEATAFTTSTAKPSLLSCPPWWMRSLWTRTIWVSCSLLPFAAGLITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVTAFAALWFLNGLAQGLGWPPCGKILRKWFEPSQFGTWWAVLSTSMNLAGSLGPILATILAQSYSWRSTLALSGSLCVVVSFFCLLLIHNEPADVGLRNLDPAPSKGKKGSSKEESTLQDLLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQERGQSALVGSSYISALEVGGLVGSIAAGYLSDRAMAKAGLSVYGNPRHSLLLLMMAGMAASMFLFRVTVTSDSPKEAFWTPALHPLAELTGFTEHEIWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVICIASTVVFFLLRNIRTKMGRVSKKAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43826-1", "uniprot_id": "G6PT1_HUMAN", "id": "O43826-1", "name": "Glucose-6-phosphate exchanger SLC37A4", "aln": "MAAQGYGYYR----TVIFSAMFGGYSLYYFN-RKTFSFVMPSLVEEIPLDKDDLGFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNIFFAWSSTVPVFAALWFLNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGGLGPILATILAQSYSWRSTLALSGALCVVVSFLCLLLIHNEPADVGLRNLDPMPSEGKKGSLKEESTLQELLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQEKGQSALVGSSYMSALEVGGLVGSIAAGYLSDRAMAKAGLSNYGNPRHGLLLFMMAGMTVSMYLFRVTVTSDSPK---------------------LWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVICAASTAAFFLLRNIRTKMGRVSKKAE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . .* : :. *:: . ** *: :: . .* *:****************************************:.*:*****..*********************:***************:*********.***********************:*******:******************* **:***** *******:***********************************:**********:**************************** ******.***:*****:.**:************ :*************************************************************************** ***..*******************", "identical_positions": 361, "similar_positions": 36, "identity": "79.34%" }, { "cls_id": "homologset.agr.RGD:620660", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29351-1", "uniprot_id": "PTN6_MOUSE", "id": "P29351-1", "name": "Tyrosine-protein phosphatase non-receptor type 6", "aln": "-----------------------MVR-WFHRDLSGPDAETLLKG------------RGVPGSFLAR----PSRKNQGDFSLSVRVDDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGILQDRDGTIIHLKYPLN-------------------------------------------------CSDPTS------------ERWYHGHISGGQAESLLQAKGEPWTFLVRESLSQPGDFVLSVLNDQPKAGPGSPLRVTHIKVMCEGGRYTVGGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYVKN-------------------------------------------------------------------------------------------------------------------------QLLGPDENS---------------------KTYIASQGCLD----ATVNDFWQMAWQ---ENTRVIVMTTREVEKGRNKCVPYWPEVGTQRVYGLYSVTNSREHD--------------------TAEYKLRTLQISPLDNGD-LVREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAG----PIIVHCSAGIGRTGTIIVIDMLMESISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQKGQESEYGNITY-------------PPAVRSAHAKASRT-----------------------SSKHKEEVY----------------------------------------------------ENVHSKSKKEEKVKKQRSADKEKNKGSLKRK--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P81718-1", "uniprot_id": "PTN6_RAT", "id": "P81718-1", "name": "Tyrosine-protein phosphatase non-receptor type 6", "aln": "----------------------MLSRGWFHRDLSGPDAETLLKG------------RGVPGSFLAR----PSRKNQGDFSLSVRVDDQVTHIRIQNSGDFYDLYGGEKFATSTELVEYYTQQQGILQDRDGTIIHLKYPLN-------------------------------------------------CSDPTS------------ERWYHGHMSGGQAESLLQAKGEPWTFLVRESLSQPGDFVLSVLNDQPKAAPGSPLRVTHIKVMCEGGRYTVGGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEAKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYVKN-------------------------------------------------------------------------------------------------------------------------QLLGPDENS---------------------KTYIASQGCLD----ATVNDFWQMAWQ---ENTRVIVMTTREVEKGRNKCVPYWPEVGTQRVYGLYSVTNCKEHD--------------------TAEYKLRTLQISPLDNGD-LVREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAG----PIIVHCSAGIGRTGTIIVIDMLMESVSTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQRGQESEYGNITY-------------PPALRSAHAKASRT-----------------------SSKHKEEVY----------------------------------------------------ENVHSKNKKEEKVKKQRSADKEKNKGSLKRNISLTPCRGLRWADRDL----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29350-1", "uniprot_id": "PTN6_HUMAN", "id": "P29350-1", "name": "Tyrosine-protein phosphatase non-receptor type 6", "aln": "-----------------------MVR-WFHRDLSGLDAETLLKG------------RGVHGSFLAR----PSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLN-------------------------------------------------CSDPTS------------ERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKN-------------------------------------------------------------------------------------------------------------------------QLLGPDENA---------------------KTYIASQGCLE----ATVNDFWQMAWQ---ENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHD--------------------TTEYKLRTLQVSPLDNGD-LIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAG----PIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGNITY-------------PPAMKNAHAKASRT-----------------------SSKHKEDVY----------------------------------------------------ENLHTKNKREEKVKKQRSADKEKSKGSLKRK--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29349-4", "uniprot_id": "CSW_DROME", "id": "P29349-4", "name": "Tyrosine-protein phosphatase corkscrew", "aln": "MLFNKCLEKLSSSLGNVVNHKLQEKQVYNNNNINNNNNNTLNNNNAYNNQRNFEYERAIQAHYGSKGRRSEERERSGKFKASKGRKAKVTPPTETPEAQEPACKNCMTHDELAQIIKGVAKGADAQRNRDNRLQRRRRPLSAQPSAAASASTSTESLHRLTPSPQASYPATPTSWTATPPQFPAAFGGASCSNSTLSLLATMRVQLHGYTWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDD---------KVTHVMIRWQDKKYDVGGGESFGTLSELIDHYKRNPMVETCGTVVHLRQPFNATRITAAGINARVEQLVKG---------GFWEEFESLQ-QDSRDTFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDVEHSVAGAEYINANYIRLPTDGDLYNMSSSSESLNSSVPSCPACTAAQTQRNCSNCQLQNKTCVQCAVKSAILPYSNCATCSRKSDSLSKHKRSESSASSSPSSGSGSGPGSSGTSGVSSVNGPGTPTNLTSGTAGCLVGLLKRHSNDSSGAVSISMAEREREREREMFKTYIATQGCLLTQQVNTVTDFWNMVWQ---ENTRVIVMTTKEYERGKEKCARYWPDEGRSEQFGHARIQCVSENS--------------------TSDYTLREFLVSWRDQP---ARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTRQSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQRSGLVQTEAQYKFVYYAVQHYIQTLIARKRAEEQSLQVGREYTNIKYTGEIGNDSQRSPLPPAISSISLVPSKTPLTPTSADLGTGMGLSMGVGMGVGNKHASKQQPPLPVVNCNNNNNGIGNSGCSNGGGSSTTSSSNGSSNGNINALLGGIGLGLGGNMRKSNFYSDSLKQQQQREEQAPAGAGKMQQPAPPLRPRPGILKLLTSPVIFQQNSKTFPKT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25044-1", "uniprot_id": "PTP1_YEAST", "id": "P25044-1", "name": "Tyrosine-protein phosphatase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAPWYIRQRDTDLLGKFKFIQNQEDGRLREATNGTVNSRWSLGVS-------------------------------------------------IEPRNDARNRYVNIMPYERNRVHLK----TLSGNDYINASYVKVN-------------------------------------------------------------------------------------------------------------------------VPGQSIEP---------------------GYYIATQGPTR----KTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEE---VVPIMELCAHSHSLNSRGN----PIIVHCSAGVGRTGTFIALDHLMHDT----------LDFKNITERSRHSDRATEEYTRDLIEQIVLQLRS---QRMKMVQTKDQFLFIYHAAKY----------------LNSLSVNQ------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .:::: : : *: . * * . .: . .* :*** **:*:::.** * .:.* :****.*:: : : ***:** * :**:* :: :. ****.* * .::** *** * . . *.: : :: * : : *: : * * . * : *: ::: :. .:.. ** ******:*****:*.:* ::.. :: . *:::*. . * .:: : : . : . : . * .* : . ", "identical_positions": 68, "similar_positions": 93, "identity": "6.87%" }, { "cls_id": "homologset.agr.RGD:620662", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1T1-1", "uniprot_id": "BAF_RAT", "id": "Q9R1T1-1", "name": "Barrier-to-autointegration factor", "aln": "-MTTSQKHRDFVAEPMGEKPVGSLAGIGDALGKRLEERGFDKAYVVLGQFLVLKKDEDLFREWLKDTCGANAKQSRDCFGCLREWCDAFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54962-1", "uniprot_id": "BAF_MOUSE", "id": "O54962-1", "name": "Barrier-to-autointegration factor", "aln": "-MTTSQKHRDFVAEPMGEKPVGSLAGIGDVLSKRLEERGFDKAYVVLGQFLVLKKDEDLFREWLKDTCGANAKQSRDCFGCLREWCDAFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75531-1", "uniprot_id": "BAF_HUMAN", "id": "O75531-1", "name": "Barrier-to-autointegration factor", "aln": "-MTTSQKHRDFVAEPMGEKPVGSLAGIGEVLGKKLEERGFDKAYVVLGQFLVLKKDEDLFREWLKDTCGANAKQSRDCFGCLREWCDAFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P026-1", "uniprot_id": "BAF_DANRE", "id": "Q6P026-1", "name": "Barrier-to-autointegration factor", "aln": "MSSTSQKHKDFVAEPMGEKSVMALAGIGEVLGKRLEEKGFDKAYVVLGQFLVLRKDEELFREWLKDTCGANTKQQGDCYSCLREWCDSFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLU0-1", "uniprot_id": "BAF_DROME", "id": "Q9VLU0-1", "name": "Barrier-to-autointegration factor", "aln": "MSGTSQKHRNFVAEPMGNKSVTELAGIGETLGGRLKDAGFDMAYTVLGQYLVLKKDEELFKDWMKEVCHASSKQASDCYNCLNDWCEEFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****::*******:*.* *****:.*. :*:: *** **.****:***:***:**::*:*:.* *.:** **:.**.:**: **", "identical_positions": 52, "similar_positions": 26, "identity": "57.78%" }, { "cls_id": "homologset.agr.RGD:620663", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0K5-1", "uniprot_id": "IGSF6_RAT", "id": "Q9Z0K5-1", "name": "Immunoglobulin superfamily member 6", "aln": "MGPVSTSRRGLRLGISLILLQVGVVGACTVSVLQPGYLEVDYTSQTVTMECTFSTTGCPAVQPKSLWFRCGTHQPEALCLDGCRNEADKFTVKETLDQNRVSLTVNRLSPNDSAIYICGIAFPNEPVPTAKQTGDGTTLVVRER-LFSREVHSLLIVLLALLAVYVTGVCVIFIVLFRSKSNTPRSRETKEDSKKK-SARRIFQEIAQELYHKRYVETSHQPEQDG-NYENRKALPSPGRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C6B7-1", "uniprot_id": "IGSF6_MOUSE", "id": "P0C6B7-1", "name": "Immunoglobulin superfamily member 6", "aln": "MGPVSARRSRLRPEISLILFQVGMVGACTVYVLQPGYLEVDYGSDAVTMECNFSTVGCPPVPPKSLWFRCGTHQPEALCLDGCRNEADKFTVKETLDPDQVFLTVNRLSPNDSAIYICGIAFPNELSPSAKHVGKGTTLVVRER-LFSKEVRSFLIVLLALLSVYITGVCVTFIVLFKSKSNGPRSRETK-GSKKK-SARRIFQEIAQELYHKRYVETSHLPEQEG-TDENRKALPNPGRA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95976-1", "uniprot_id": "IGSF6_HUMAN", "id": "O95976-1", "name": "Immunoglobulin superfamily member 6", "aln": "MGTASRSNIARHLQTNLILFCVGAVGACTLSVTQPWYLEVDYTHEAVTIKCTFSATGCPSEQPTCLWFRYGAHQPENLCLDGCKSEADKFTVREALKENQVSLTVNRVTSNDSAIYICGIAFPSVPEARAKQTGGGTTLVVREIKLLSKELRSFLTALVSLLSVYVTGVCVAFILLSKSKSNPLRNKEIKEDSQKKKSARRIFQEIAQELYHKRHVETNQQSEKDNNTYENRRVLSNYERP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..* . : .***: ** *****: * ** ****** ::**::*.**:.***. *..**** *:**** ******:.*******:*:*. ::* *****::.*************. . **:.* ******** *:*:*::*:* .*::**:**:***** **:* :**** *.:* * .*:** *****************:***.: .*::. . ***:.*.. *.", "identical_positions": 139, "similar_positions": 61, "identity": "57.68%" }, { "cls_id": "homologset.agr.RGD:620664", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10591-1", "uniprot_id": "HSP71_YEAST", "id": "P10591-1", "name": "Heat shock protein SSA1", "aln": "---MSKAVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--GKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDTVTKKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLY-QAGGAPGGAAGGAPGGFPGGAPPAPEAEG---PTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P10592-1", "uniprot_id": "HSP72_YEAST", "id": "P10592-1", "name": "Heat shock protein SSA2", "aln": "---MSKAVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--GKEEH-VLIFDLGGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAG--DKLEQADKDAVTKKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLY-QAGGAP---EGAAPGGFPGGAPPAPEAEG---PTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22202-1", "uniprot_id": "HSP74_YEAST", "id": "P22202-1", "name": "Heat shock protein SSA4", "aln": "---MSKAVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--SQKEHNVLIFDLGGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIMSKFYGAAGGAPG--AGPVPG--AGAGPTGAPDNG---PTVEEVD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P17156-1", "uniprot_id": "HSP72_MOUSE", "id": "P17156-1", "name": "Heat shock-related 70 kDa protein 2", "aln": "MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGEMKTFFPEEISSMVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNAVESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQ----------GGPGGG-------GSSGG----PTIEEVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14659-1", "uniprot_id": "HSP72_RAT", "id": "P14659-1", "name": "Heat shock-related 70 kDa protein 2", "aln": "MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGEMKTFFPEEISSMVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNAVESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQ----------GGPGGG-------GSSGG----PTIEEVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54652-1", "uniprot_id": "HSP72_HUMAN", "id": "P54652-1", "name": "Heat shock-related 70 kDa protein 2", "aln": "MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQ----------GGPGGGSGGG-GSGASGG----PTIEEVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11147-1", "uniprot_id": "HSP7D_DROME", "id": "P11147-1", "name": "Heat shock 70 kDa protein cognate 4", "aln": "-MSKAPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFDAKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKK--AVGERNVLIFDLGGGTFDVSILSIDDG-IFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEAEKYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQLADKEEYEHRQKELEGVCNPIITKLYQGAGFPPGGMPGGPGGMPGAAGAAGAAGAGGAGPTIEEVD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O97125-1", "uniprot_id": "HSP68_DROME", "id": "O97125-1", "name": "Heat shock protein 68", "aln": "----MPAIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFDAKRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAYLGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKN--LKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMDKSQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLLVDVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNVLGTFDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLSEAEKYAEEDERHRQRIAARNQLETYLFGVKEAAENGG--DRISAADKSSIVERCSEAMKWLDSNTTAEKEEYEYKLKELEQFCSPIMTKMHK----------GGGDGQ--QAPNFGQQAGGYKGPTVEEVD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***********. * .:*:*************:*.***:***********.**** :::*********.*:*. : * **:**.::. .*** :.* :*. * * **:****:* **** ** :** * .**:******************:*:*:*************:******: *: **************:*:*::* :***::*************.*:*..: :***** ***: .* *::******.**********:::*:***:*:** ***:.::******* .****.*::****.* *:*:**. :.:************:*.*: : *.** * *************:***** **:*. :*:**:**:***********:*: ** **: ** *::: *:**:***..* :**:****: *****:**.*:*:*:********:*:****:*:******:* ::.*.: ::***.*******: **::*: ***:: *** . : : ::* :*: : :* : .: :: * : ..:.: *** . * .:*:. : ***: ...**::*:: * * . **:****", "identical_positions": 369, "similar_positions": 161, "identity": "56.34%" }, { "cls_id": "homologset.agr.RGD:620665", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M9PB21-1", "uniprot_id": "M9PB21_DROME", "id": "M9PB21-1", "name": "Fatty acid synthase", "aln": "------------------------------------------------------------------------------------------------------------------MPSRKKAQGESAAG---------EDADIVISGLSGKLPESSNIEEFKYNLLNGIDMVTDEPRRWEAGIYGLPERMAKMKDSDLEKFDDKFFSVHQKQAELMDPCMRMLLELTHEAIIDAGINPVQLRGSRTGVYIGLSFVETEHEIPNMEPSSINGYCLTGCARAMFANRISYTFDFKGPSFIVDTACSSSLVALNHAFADMRAGRCDYALVAGVNLILKPIFALQFLRLGIVSHDGSCKTFDAAANGYARADTCAVVLLQRRKEAKRVYASILNVRTNTDGFKEQGVTFPDGRMQQALLEETYSEIGLNPDEVVYVEAHGSGTPVGDDQEANMLSNFFCRPSRSTPLLIGSVKSNMGHAEPASGVSALAKMIIAMEEGIIPKNLHYRTPNPSVPALVEGKLKVVDRNLPWQGGIVGLNSFGFGGANAHVVLKSHTKAKEPKACPKAGEAEQSLSLVTCSGRTEDAVNQLLKVATEQRHDQELLTLINDIHSHPIPLHPFRGYAVLGTSGCVKE-----EVLPYEEEERPIWFVYAGMGSQWARMAKDLMQLEVFRNSIQHCAEVLAQVDFDLIDVLTRSTERTFDNMLYSFVSVSAVQVALTDLLRVLDIRPDGIIGHSAGELGAAYMDGCLTAEQTVLAAYWRGRSVLDTPDLPRGKMAAVGLSWEQIGSQIPKDCYPVCHNSDDNCTVSGPPSSMDAMIEDLTAKGIFVREVGSGGYAFHSPYIEGAAPMLRRSLERLITEPKKKSIRWLSTSVKEAEWDSEKNHLASAGYFINNLISPVLFHQAVKRIPQNALIVEIAPHGLFRAILR-SLSPQISYVSLMQRGHANNFEFLLSQLGRLYAAGGQPQILKISPSIPYPVSRGTPMLGSLVGWDHTQKWNYPKFKGGR-----QAGQLSVELDLGKEE-NVYLAGHTIDGRVLFPATGYMTLAWMSLAQQ-QGLDYLRTPVLFEDVVFHRATILSVGTVVKLTLNFFPGSSSFEICEGTSLVTSGKIRLVSNVQQ-EQLQLSSLPGIAGSNK-----LSTKDIYKELRLRGYDYTGVFQGILESDISAVTGQLQWADNWISFMDTMLQFRILSNDIRELYVPTGIERALIDPLKHLELAKKHQQK------LTVNWHRNISVVKCGGVEIHKMKTAQTQRRSGGQSPPSLERYRFWPHSQHLGQRE----EQEKSRSTALAVAIQLIIENS-GGAVKLKGVE--------------------LAGSRSTLDALSAVQLLELIERE-------PILVG-----------DMAVVTSSSNESELGEQLKEHG-----------------IRVIVKDIKAGAVEQQCH----------------------------FVYSVNMLAQNSVKDLQHCLDSLKSDSGFLLLEEAAS----------------------RYNIIGKEKLNKLKLVSVLEQFFGTDRVLVLVRKLSKVQSSQALTLHLTNKQFKWVNELKNSIAKAQAEEKNLYLVAQGEPNSGALGLMNCLKREAGGHFLRLYLILDEG----VPQFSLDDPFYAAQLAKDLVVNVYRNGSWGSYRHLKMES-RPPMLPVEQAYVNTLVKGDLSSLRWIESPRS---SPIQSQLEPCTVYYAPLNFRDVMLASGKLGVDALPGDLAYQDCVLGLEFAGRDSC-GRRVMAMVTAKSLATNCLANRNLLWEVPSKWTMEQASTVPCVYATVYYALVVRGQMKEGERILIHAGSGGVGQAAISVALAHGLTVFTTVGSKEKREFLLKRFPKLKAKNIGNSRDTSFEQLIMSETHGNGVELVLNSLSEEKLQASIRCLALNGRFLEIGKFDLSNNTPLGMSVFLKNTSFHGILLDSVMEGEEEMQLMVAKLVAEGIKSGAVQPLPTTVFAEQEIEKAFRFMASGKHIGKVVIKVRLEEE-QQAALPRLRQIQAIPRSYMHPEKSYILVGGLGGFGLELANWLVSRGARFLVLSSRSGVKSGYQALMIRRWHDRGVQVQIDTNDVTTAVGCQRLLEVSNKLALVGGIFNLAAVLRDGLIEDQSPKNFEKVSAPKLLATIHLDKISREICPALEYFVCFSSLSCGRGNMGQTNYGLANSTMERICEQRQEYGYPGTAIQWGAIGDTGLIIEHMGN-NETVVGGTLPQRMISCLETLDLFLQQPHPVMASMVVAEK---RKTEQANRLSLIATIANIMGLRDVKSVSDKTTLFDLGMDSLMSTEIKQTLERHFDLVLSAQEIRQLTFSALRQID--AQEPPSASVSSPSAS-STLSRIKEEACVEVQ-PQSDETRKVFAKEVLPQEVMVRLRSKAPVASEDPAVFFLAPIEGFT-IAVEALAASLTCPAYGLQCTEQVPLDSIEACAAYYLRQIQKLQPL-GPYHIVGYSYGCLLAHAIAVALEQRRFGVK----VIMLDGAPTMASGYVQEAKKQTDD----LNRQQSMTLAYFGALLADVDYNQVLLQLLDGVQTWPSKLDKLADTLAG-YTQQTREVIKKAACMFK-QKLLLSESYKGAKQLHSDVVLIKSAEH---NAIMAQDYGLKEICSAQIDMHVVEGTHRTFLKEPHTLQIIERVLRKRP------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z001-1", "uniprot_id": "B7Z001_DROME", "id": "B7Z001-1", "name": "Fatty acid synthase", "aln": "MPLQLNLLQAVDQPHPVAFKPNNCSTHQPQHSPSTQNNGKSARANRRRRRRRNKQQQNSQQPDAFRDTDAQLTPSTSSSTPHSAPNDRQDHLNSQFNPESINMPARFAEEVITAEPAQRAAPQLDLGGGHYVPRQQHLNDEIAITGFSGRLPESSTIEEFKQNLFDGVDMVNDDPRRWERGLYGLPDRIGKLKDSDLENFDQQFFGVHQKQAECMDPLLRMLLELTHEAIIDAGLNPSDLRGSRTGVYIGVSNSETEQHWC-SDADRVNGYGLTGCARAMFANRISFTFDFKGPSYSIDTACSSSLYALEQAFSDMREGKVDNALVAGAGLILKPTMSLQFKRLNMLSPDGSCKAFDESGNGYVRSDGCVVLLLQRTSAARRVYASILNVRTNTDGFKEQGITYPIGKMQNRLIRETYEEIGLNPADVVYVEAHGTGTKVGDPQEVNSITDFFCK-DRTTPLLIGSVKSNMGHSEPASGVCSVAKILIAMEEGVIPGNLHYNKPNPDLYGLVDGRLKVVDRNLPWNGGIIGLNSFGFGGANAHVILKSNPKPK--ALTPKD----GALKVVLASGRTFEAVEQLLESASTNADDDEYLQLINEIHSKAIPNHFFRGYGVVSSKGTHQR-----EVIESNDDKRPIWYIYSGMGSQWASMAKDLMKIEAFAKTIQRCADVLKPEGVDLIDVLTRSTDKSFENILNSFISIAAMQVALTDLLSSLGIHPDGIVGHSVGELGCAYADGCFTPEQTVLAAYWRGKSILDT-QLAKGKMAAVGLSWEDAHSRVPSDCFPVCHNSEDNCTISGPEASIEALVAKLNAEGVFAKAVNSSGYAFHSKYIAEAGPKLRKSLEKIIPNAKNRTARWISTSIPESAWNTPVAKQSSAAYHVNNLLSPVLFHEALQHVPKNAISVEIAPHGLLQAILKRALGPDATNLSLVKRGHENNVEFFLTNVGKLFAAGAQPQVLTLVRPISYPVGRGTPMLNSKVGWDHTQKWLVAKFGKET-----SSGETIVEVDLSKED-DAFLAGHTIDGRILFPATGYMTLAWQTFAKM-QGSEFHKTPVVMENLVFHRATILNKNAVVKFGINFFDGTGAFEICESGSLAVSGKITIPESIDN-EELPLEEQTPSAVAKE-----LGTNDVYKELRLRGYDYGGIFRGIVRSDTVASTGKLQWVDNWISFMDTMLQFSILSKNLRELYLPTRIERAVINPAKHFELLSALTKEEQVETGLPVQWYSDINVIKSAGVELRGLKANLAQRRPGTQAPPTLERYQFVPNINTTDLNE----NSEKARLHALDVAIQVIIENS-SGAVKLKGVE--------------------LANGR-NPDVLVANRLLQIIEGE-------PVLTG-----------DVAVVTSNNNEETITAALGDSG-----------------VRVVSKDVLKEPVEQNCH----------------------------FVFGIDVLSRPDTKTLENSIASIR-ENGFLILEETLP----------------------TYTKTGRALLTKFGFVAVQEQSLGATRVLVLARKAVDLKTRKSVVVVATEQNFNWVDDLKAALATAATEEQYVYVVCQGEELFGAVGLMTCIKNENGGKLARLVFVQDAK----AEKFSLTSTLYRQQLEKDLISNVLKNGAWGTFRHLKLET-QQATLQVEHAYVNALVKGDLASLKWIEAAQADTAATVDKNLETCTVYYAPINFRDVMLTSGKLAADALPGDLAEQDCVLGLEFAGRDTQ-GRRVMAMVPAKSLATTCVASKRMMWQIPEKWTMEEASTVPCVYSTVYYALVVRGQMKKGEKILIHAGSGGVGQAAISVALAHGLTVFTTVGSKEKREFLLKRFPKLQERNIGNSRDTSFEQLVLRETKGRGVDLVLNSLSEEKLQASIRCLGLNGRFLEIGKFDLSNNSPLGMSVFLKNTSFHGILLDSVMEGEEEMQNQVVSLVAEGIKTGAVVPLPTSVFNDQQVEQAFRFMASGKHIGKVVIKVRDEEAGKKALQPKPRLINAIPRTYMHPEKSYILVGGLGGFGLELTNWLVTRGARYIVLTSRSGVKTGYQGLMIRRWQERGVKVVIDTSDVTTAAGAKKLLENSNKLALVGGIFNLAAVLRDALIEDQTAKDFKTVADPKVTATKYLDQFSRDICTELDYFICFSSVSCGRGNIGQTNYGLANSAMERICEQRQVSGFPGTAIQWGAIGDTGLVLENLGD-NDTVIGGTLPQRMPSCLQTIDLFLQQPHPVVASMVVAEK---RKSDQSAGVSLIATIANILGLRDTKNIQDGASLADLGMDSLMSAEIKQTLERNFDIVLSAQEIRQLTFGALKAMDGGADVKPAAAAPAAAAG-VPEANITSGGSSRTASPMGDGTQVVFTTSLIPTEAIVQLDTKAPANSKQSPIFFISPIEGFA-SALEPLAKRLEVPAYGLQYTEAVPSDSLESAAKFFIKQLRTVQPK-GPYKLAGYSFGCLLTYVMAGILEETNEVAN----VIMLDGAPSYVNWYTSSFKQRYTDGTNADNDNQSYGLAYFGIVLANIDY-KALVRLLIVIPTWEEKLERFAELMSN-EITQPVETIKKSATLFY-KKLELADGYQPTLKLKTNVTLVKPTDN---SAKLDEDYRLKEVCTKPVEVHTVEGNHRTFLIEDQSLKTIQSILKRLFN-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P12785-1", "uniprot_id": "FAS_RAT", "id": "P12785-1", "name": "Fatty acid synthase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLK--DLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALS-RDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAAIVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGNGYCRAEAVVAVLLTKKSLARRVYATILNAGTNTDGCKEQGVTFPSGEAQEQLIRSLYQPGGVAPESLEYIEAHGTGTKVGDPQELNGITRSLCA-FRQSPLLIGSTKSNMGHPEPASGLAALTKVLLSLENGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGIVGINSFGFGGANVHVILQPNTQQA-----PAPAPHAALPHLLHASGRTMEAVQGLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGHVQ------EVQQVPASQRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEALKPLGVKVSDLLLSTDEHTFDDIVHSFVSLTAIQIALIDLLTSMGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDA-NLPAGSMAAVGLSWEECKQRCPPGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFAKEVRTGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGVKPSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGIDINPNALFPPVEFPVPRGTPLISPHIKWDHSQTWDIPVAEDFPNGSS-SSSATVYNIDASSESSDHYLVDHCIDGRVLFPGTGYLYLVWKTLARS-LSLSLEETPVVFENVTFHQATILPRTGTVPLEVRLLEASHAFEVSDSGNLIVSGKVYQWEDPDS-KLFDHPE-VPIPAESE-SVSRLTQGEVYKELRLRGYDYGPHFQGVYEATLEGEQGKLLWKDNWVTFMDTMLQISILGFSKQSLQLPTRVTAIYIDPATHLQKVYMLEGDTQ---VADVTTSRCLGVTVSGGVYISRLQTTATSRRQQEQLVPTLEKFVFTPHVEPECLSESAILQKELQLCKGLAKALQTKATQQ-GLKMTVPGLE---------DLPQHGLPRLLAAACQLQLNGNLQLELGEVLARERLLLPEDPLISGLLNSQALKACIDTALENLSTLKMKVVEVLAGEGHLYSHISALLNTQPMLQLEYTATDRHPQALKDVQTKLQQHDVAQGQWDPSG-PAPTNLGALDLVVCNCALATLGDPALALDNMVAALKDGGFLLMHTVLKGHALGETLACLPS-EVQPGPSFLSQEEWESLFSRKALHLVGLKKSFYGTALFLCRR--LSPQDKPIFLPVEDTSFQWVDSLKSILATS--SSQPVWLTAMNCPTSGVVGLVNCLRKEPGGHRIRCILLSNLSSTSHVPKLDPGSSELQKVLESDLVMNVYRDGAWGAFRHFQLEQ-DKPEEQTAHAFVNVLTRGDLASIRWVSSPLKHMQPPSSSGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWASRDCMLGMEFSGRDKC-GRRVMGLVPAEGLATSVLLSPDFLWDVPSSWTLEEAASVPVVYTTAYYSLVVRGRIQHGETVLIHSGSGGVGQAAISIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFANSRDTSFEQHVLLHTGGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLKNVTFHGILLDALFEGANDSWREVAELLKAGIRDGVVKPLKCTVFPKAQVEDAFRYMAQGKHIGKVLVQVREEEPEAMLPGAQPTLISAISKTFCPEHKSYIITGGLGGFGLELARWLVLRGAQRLVLTSRSGIRTGYQAKHVREWRRQGIHVLVSTSNVSSLEGARALIAEATKLGPVGGVFNLAMVLRDAMLENQTPELFQDVNKPKYNGTLNLDRATREACPELDYFVAFSSVSCGRGNAGQSNYGFANSTMERICEQRRHDGLPGLAVQWGAIGDVGIILEAMGT-NDTVVGGTLPQRISSCMEVLDLFLNQPHAVLSSFVLAEKKAVAHGDGEAQRDLVKAVAHILGIRDLAGINLDSSLADLGLDSLMGVEVRQILEREHDLVLPIREVRQLTLRKLQEMSSKAGSDTELAAPKSKND-TSLKQAQLNLSILLVNPEGP-----------------TLTRLNSVQSSERPLFLVHPIEGSI-TVFHSLAAKLSVPTYGLQCTQAAPLDSIPNLAAYYIDCIKQVQPE-GPYRVAGYSFGACVAFEMCSQLQAQQGPAPAHNNLFLFDGSHTYVLAYTQSYRAKLTPG--CEAEAEAEAICFFIKQFVDAEHSKVLEALLP-LKSLEDRVAAAVDLITRSHQSLDRRDLSFAAVSFY-YKLRAADQYKPKAKYHGNVILLRAKTGGTYGEDLGADYNLSQVCDGKVSVHIIEGDHRTLLEGRGLESIINIIHSSLAEPRVSVREG---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19096-1", "uniprot_id": "FAS_MOUSE", "id": "P19096-1", "name": "Fatty acid synthase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLK--DLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALS-RDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAALVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGSGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGEVQEQLICSLYQPAGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCA-FRQAPLLIGSTKSNMGHPEPASGLAALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNTRQA-----PAPTAHAALPHLLHASGRTLEAVQDLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGRVQ------EVQQVSTNKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGVKVSDLLLSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDA-HLPPGSMAAVGLSWEECKQRCPAGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFAKEVRTGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGINVNPNALFPPVEFPAPRGTPLISPHIKWDHSQTWDVPVAEDFPNGSS-SSSATVYSIDASPESPDHYLVDHCIDGRVIFPGTGYLCLVWKTLARS-LGLSLEETPVVFENVSFHQATILPKTGTVALEVRLLEASHAFEVSDTGNLIVSGKVYLWEDPNS-KLFDHPE-VPTPPESA-SVSRLTQGEVYKELRLRGYDYGPQFQGICEATLEGEQGKLLWKDNWVTFMDTMLQVSILGSSQQSLQLPTRVTAIYIDPATHRQKVYRLKEDTQ---VADVTTSRCLGITVSGGIHISRLQTTATSRRQQEQLVPTLEKFVFTPHMEAECLSESTALQKELQLCKGLARALQTKATQQ-GLKAAMLGQE---------DPPQHGLPRLLAAACQLQLNGNLQLELGEALAQERLLLPEDPLISGLLNSQALKACVDTALENLSTLKMKVAEVLAGEGHLYSRIPALLNTQPMLQLEYTATDRHPQALKDVQTKLQQHDVAQGQWNPSD-PAPSSLGALDLLVCNCALATLGDPALALDNMVAALKEGGFLLVHTVLKGHALGETLACLPS-EVQPAPSLLSQEEWESLFSRKALHLVGLKRSFYGTALFLCRR--AIPQEKPIFLSVEDTSFQWVDSLKSTLATS--SSQPVWLTAMDCPTSGVVGLVNCLRKEPGGHRIRCILLSNLSNTSHAPKLDPGSPELQQVLKHDLVMNVYRDGAWGAFRHFQLEQ-DKPKEQTAHAFVNVLTRGDLASIRWVSSPLKHTQP-SSSGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWASRDCMLGMEFSGRDRC-GRRVMGLVPAEGLATSVLLSSDFLWDVPSSWTLEEAASVPVVYTTAYYSLVVRGRIQRGETVLIHSGSGGVGQAAISIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFANSRDTSFEQHVLLHTGGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLKNVTFHGILLDALFEEANDSWREVAALLKAGIRDGVVKPLKCTVFPKAQVEDAFRYMAQGKHIGKVLVQVREEEPEAVLPGAQPTLISAISKTFCPAHKSYIITGGLGGFGLELARWLVLRGAQRLVLTSRSGIRTGYQAKHIREWRRQGIQVLVSTSNVSSLEGARALIAEATKLGPVGGVFNLAMVLRDAMLENQTPELFQDVNKPKYNGTLNLDRATREACPELDYFVAFSSVSCGRGNAGQTNYGFANSTMERICEQRRHDGLPGLAVQWGAIGDVGIVLEAMGT-NDTVIGGTLPQRISSCMEVLDLFLNQPHAVLSSFVLAEKKAVAHGDGDTQRDLVKAVAHILGIRDLAGINLDSTLADLGLDSLMGVEVRQILEREHDLVLPMREVRQLTLRKLQEMSSKTDSATDTTAPKSRSD-TSLKQNQLNLSTLLVNPEGP-----------------TLTQLNSVQSSERPLFLVHPIEGST-TVFHSLAAKLSVPTYGLQCTQAAPLDSIPNLAAYYIDCIKQVQPE-GPYRIAGYSFGACVAFEMCSQLQAQQGPAPTHNNLFLFDGSHTYVLAYTQSYRAKMTPG--CEAEAEAEALCFFIKQFLDVEHSKVLEALLP-LKSLEDRVAASVDLITKSHHSLDRRELSFAAVSFY-HKLRAADQYKPKAKYHGNVTLLRAKTGGTYGEDLGADYNLSQVCDGKVSVHIIEGDHRTLLEGSGLESIINIIHSSLAEPRVSVREG---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49327-1", "uniprot_id": "FAS_HUMAN", "id": "P49327-1", "name": "Fatty acid synthase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLK--DLSRFDASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEALS-RDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQCPAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLARRVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVGDPQELNGITRALCA-TRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPP-----PAPAPHATLPRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGP------EVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLSTDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAVLAAYWRGQCIKEA-HLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFEFVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEAQWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCTIIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSLAWDVPAAEDFPNGSG-SPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLARA-LGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQWDDPDP-RLFDHPE-SPTPNPTE-PLF-LAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRLLWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQ---VADVVVSRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQLCKGLVQALQTKVTQQ-GLKMVVPGLDGA---QIPRDPSQQELPRLLSAACRLQLNGNLQLELAQVLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLLSPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPAD-PAPSALGSADLLVCNCAVAALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESLFSRVSLRLVGLKKSFYGSTLFLCRR--PTPQDSPIFLPVDDTSFRWVESLKGILADED-SSRPVWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGDLVMNVYRDGAWGAFRHFLLEE-DKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQP-TCPGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDAS-GKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEEPEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGIRTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLLENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSAMERICEKRRHEGLPGLAVQWGAIGDVGILVETMST-NDTIVSGTLPQRMASCLEVLDLFLNQPHMVLSSFVLAEK-AAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLRSLLVNPEGP-----------------TLMRLNSVQSSERPLFLVHPIEGST-TVFHSLASRLSIPTYGLQCTRAAPLDSIHSLAAYYIDCIRQVQPE-GPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGSPTYVLAYTQSYRAKLTPG--CEAEAETEAICFFVQQFTDMEHNRVLEALLP-LKGLEERVAAAVDLIIKSHQGLDRQELSFAARSFY-YKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F5V3-1", "uniprot_id": "E7F5V3_DANRE", "id": "E7F5V3-1", "name": "Fatty acid synthase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MEDIVIAGISGRLPESNNLEEFWQNLFNGVDMVTEDDRRWKPGLYGLPRRNGKLK--EIDRFDAAFFGVHPKQAHTMDPQLRLMLEISYEAIVDGGINPVSMRGSKTGVYIGVSGSEAGEAFS-KDPEELLGYSMTGCQRAMFANRLSYFFDFNGPSTAIDTACSSSLLALENAFNAIRHGKCDAALIGGVNLLLKPNTSVQFMKLGMLSPEGTCKSFDASGNGYCRSEAAVAVLLTKKSMAKRIYATVLNAGNNTDGYKEQGVTFPSGEMQQRLVRSLYQEANISPEQVEYIEAHGTGTKVGDPQEVNGIVSVFCQ-SQRDPLLIGSTKSNMGHPEPASGLAALAKVVLSLEHGVWAPNVHFNEPNPDIPALTDGRLCVVSKPTPVRGGIVGINSFGFGGSNVHVILSPHVSDS-----SDKTPAPSVPRLLQASGRTEEAVTALFSNAQQHQENSSYLSLLNDVSGVPTAGMPYRGYTLIGAQGELT------EVQQTQPTPRPLWYICSGMGTQWAGMGQSLMQLSEFRESIKRSDIALKDTGLCVSRLLMEADESTFEDTVHAFVGLAAIQVAQIDMLRKMGLEPNGIVGHSVGELACGYADGSLSHSEAILAAYWRGRCIKEA-NLPPGGMAAVGLTWEECKAQCPQGVVPACHNAEDTVTISGPQDSVSKFVAQLKESGVFAKEVRSAGVAFHSYYMASIAPALLSALQKVIKSPRPRTARWISTSIPQSDWESPLALYSSAEYHVNNLVSPVLFQEGLNHVPDNAVVVEIAPHALLQAILKRSLKPTCSILPLMKRGHANNLEFFLSHVGKVYMNGINVDSNKLYPAVKYPVPRGTPLISPYIQWDHSQSWDVPKVEDFPAGSGGSTSATVYNIDMNPESPDYYMIGHCIDGRVLYPATGYLVLAWRTLMRS-LGTVMDHTPVTFEDVTIHRATILPKTGSVQLEVRLMPATNRFEVSENGNLAVSGKVSVLEDSGL-DAFHAELNKPITADNEDPKLRLKSGDIYKELRLRGYDYGKTFQGILESNNAGDSGKLHWTGNWVTFLDTMLQMIVVGLPGRSLRLPTRIRSVCVDPKLHEERVNDYEGDQK---AVNVFVNRCLDNITAGGVQICGLHATAAPRRQQQQTPPTLEEFVFVPYEDADCLRTNEKLADQLRHCKGLVQRLQRKLAKQ-GVKISIPGLEGASEGQLIEAEAEKGLLRLLSVLCGLELNGNLRSELEQTVQKERDCLLQDPLLNGLLDSQALRHCLDTALENSTPGKFKVLEALAADGRVFSQAVSLLNIQPMLRLDYTASDISADQLSAQQSSLEEQGISTAQWDPLQGPVTGGLDGADLVVCNCAVGSATNPALLIENLTSAAREGGFILLHTLLRGDTLGETVAFLTS--QNNRKGLLTQTEWEELFQKASLNVVMLRKSYYGSALFLCRRSQQSSQKQPIHIFVDPTDYKWVETLKSTLAES--SDIPVWLIATKG-HNGVVGMVNCLRQEPGGNRIRCTFVSNLSKGAAVPSLLPNEKVMKALLKKDLVMNVHRDGLWGVFRHQLLTQ-DLSEELTEQAYVNVLTRGDLSSLRWIASPLRHFVA-SSPNVQLCRVYYSSLNFRDIMLATGKLPPDAIPGDVALQQCMLGMEFSGRDPS-GRRVMGLLPAKGLATCVDADKRFLWDVPSSWTLEQAASVPVVYATAYYSLVVRGRLRPGESVLIHSGSGGVGQAAIAIALSMRCRVFTTVGSKEKKQYLQERFPQLTAESFANSRDSSFEQHVMLNTQGKGVDLVLNSLAEEKLQASLRCLARHGRFLEIGKYDLSNNTPLGMALFLKNVAFHGILLDALFEEGNREWEEVSDLLKKGISSGVVQPLRTTVFERNQVEEAFRYMAQGKHIGKVLLQVRSEESSSSGPAVSALSIPAICRTFCPASLSYIITGGLGGFGLELAQWLTERGARKLVLTSRSGIRNGYQAKRVREWQAMGIQVLVSTSDVSTLDGTERLITEACRLGPVGGIFHLAMVLKDGMLENLTPQEFIEVNRPKYDGTINLDSVTRQKCPQLQQFVVFSSVSCGRGNAGQSNYGFANSTMERICEQRRQENLPGLAVQWGAIGDVGVVLETMGG-NDAVIGGTLPQRMSSCLEVLDRFLCQQRPVMSSFVLAEKVVVTKGEGSGQKDLVEAVAHILGVRDVNSLNADASLADLGLDSLMGVEVRQTLERDYDIVMAMREIRQLTINKLRELSKQSGGKEE--SPVKRSG--AQALLESDLSRMLVNPDGP-----------------TMAPLNEVQSAERPLFLVHPIEGSI-AAFRTLTAKLSVPCYGLQCTKAAPLDSIQSLAAYYVECVRQVQLE-GPYRIAGYSFGACVAFEMCSQLQLAKCPV---EYLFLFDGSHSYVAAYTQSYRAKLTPG--KESEAETEALCAFIQQFTGIEYNKLLETLLP-LSDLEARVDKAVDLITSSHKNVSRDMLHFAASTFY-HKLKAADRYVPTSKYHGNVTLLRAKASSEYGDGLGSDYKLHEVCDGKVSVHVIEGDHRTFLEGEGVESISSIIHSSLSEPRVSTREG---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PLB8-1", "uniprot_id": "Q7PLB8_DROME", "id": "Q7PLB8-1", "name": "Fatty acid synthase", "aln": "-----------------------------------------------------------------------------------------------------------------MESTKNKKYSRSFP--------DTDGDDIVISGMAGKFPNCRNITEYQYKLYNKIDMVDDDERRWRHFNPEIPKRSGKIC--DLEKFDATFFGVHFKQAHTMDPQTRILIETAYEAVIDSGVNPKSLRGSKTGVYIGSCISESEKTWF-YEKVSSGGFGITGCSRAMMANRISYCLGLEGPSFLLDTACSSSMYALDNAFSAIRNGEIDAAIIGGSNLLLHPFVTLQFARLGVLAPDGFCRPFDKNASGYTRSETINCLFLQKKKHAKRVYASIVYSKTNCDGYKPEGITYPSGIVQEKLLDQFYKDIDHKPSDLGYLEAHSTGTVVGDPEECKAIDNVLCS-QREEPLLVGSVKSNVGHSEAASGICSLVKACFAFETGLIAPNINFTEVKQIIAPLAEGRLIVVKDVVPLPKPYIGINSFGFGGANAHALLKGYPKSK----NNFGIPADDVPRLLTWAGRTEEAVEEIFNAVEKNPLDAEFIGLLQNIQEEDVSGMVFRGYAIFAKQGTGPCKLLAKDVQHYTGLQRPIVWVYSGMGSQWNQMGNSLMIIPRFRESVEICHQILLAKGLNLIHILTSNDPEVYQNILNSFVGIAAVQIGLTDVLRSLNIQPDYIIGHSVGELGCAYADGGLTAQQMILAAYYRGRVSVDL-EKIRGSMAAVGLGYKTVLHMLPKSIETACHNGPDSCTISGPVDDVAQFVADLKTKGIFAKEVPCSNIAYHSKYISHMGPPLLNYMNEIIPHPKPRTKKWLSTSVPKIDWNKDKAKFCSAEYHTNNLLNSVLFDETFSLIPKNSLTIEVAPHGLLGAILKRSMPS-GVHIPLTNRGNQNNASFFLSALGKIYLNGVLLPAANLYERIQFPVSRTTPSVSSLIRWDHSEDWFVTKYENMKTK---SSGERVFSVNLASDN-EEFLSGHIIDGKILVPATCYLQYVWETFSLMYHGPSYMDVPVEFEDIRFIRATSMPVDGKVDLTVMIHYGTGHFEITEMGSLVVTGIIRETENPSIPEVYNFQSKSKFP--------MIAKKDFYKELKLRGYHYNGAFQAVNLARSDGLFGRVQWNYNWVTFMDAMLQIQILGTDSRNLLLPTKIRKLKINGVHHFDLMTKMDPENR---VFDVYVDPMYDRIIAGGIEIFGLHASLVQRRR-PPGIPVLEEYVFLPFFSSS----------ILSLKNAARVCVQIAIENNPTLKLKLVEVG-------------------------ADGKNHMLTEFIEAIQDL-------PVITG-----------DYILLTSQNLED-----------------------------LPGVHIENGSLSTQTN---------------------------CHIIIIGGYEEDEVHEKITSAYNVLVDNGYIVFRQKCA-----------------------KNVSCKIAEKFRTISKIPINNTEENLVLLQKISKKLTVPPVLVKVSQHDKTFEWILELQSAIITK----APVVVYSFNEKLNGQIGLVNCLRKEPDGNLIRCFFIDDDS----APDFDLSHPFYSTQYSLGLAFNIYRNGSWGSYRHLQLLKNDQPSKRLDHIYGNVIQRGDLSSLQWLKGPFN-------SQNCHIKIAFSSLNFRDVMLATGRLAVELYGSSRIDQNCVLGFEYSGINMLTGRRIMSMVVKGGVASYVEKPSKLIWDIPDDWSLEEAATVPVVYITVYYAFFMATDIRKGKSILIHAGTGGIGLAAIRVALAYNLEVFTTCSTANKKEFLLKTFPKLKESHIGNSRNTSFELMVHRETNGKGVDFVLNSLSEEKLLASLRCLGKSGHFLEIGKYDMANDNKIGLGCFLKEITFHAVLADSLLVAPDEDIWHLKSLIDMDISNGIIQPLPVKVFLAHEIEQAFRHLIGGKHIGKVVIQVR-----EQPHDPSTLPVRVLNQVYFKHNHTYVIPGGLGGFGMELADWMAIRGARKLLLSSSRGITKDYQLYRIALWKTYGCEVAISTADITSKKGCAQLLSEANGMGPVGGIFNLAVVLKDCIFSNQNVNQFLECFAPKAIATTYLDDLSRIYCPELEHFVVFSSVSCGRGNAGQSNYGMANSVMERIIEHRNREGFPGKAIQWGAIGEVGLVADMAEDKIDMEIGGTLQQRISSCIQELDHLLCADASIVSSMVVAEK----RTMRSGQGNVIDAVMNIMGIRDLKSVSLSTTLSEMGMDSLMAVEIKQTLERDFELILTPQDLRHLTFQKLQEFIDAKEKENTDGIQIIFASDNKLLGMELLIRNLGDEANCDQIIIP------------LQTSAAPSKQNLQPNIIIPGLEGTAGRAWYQLGSKLQSPAIVLQLHQFAHLENLKDVAQQSFDQIKLILKQTEPFYIIAYSYGTFVALLLAEMLENSGFRGH----LMLLDGAPHFLKRLTNLHLGEQFSD----NDLYDLLFSSIVNHIFPEASKESMSTVFHQVDCLSDKMSLFMNYVEKQNMYSKKYSSTMVKAMFNRVKMAASFDLDGIIKIKSPITLVRPAEAS--LQDIDEDYCISLLTSGVVTLKVIEGNHTTMLDNPSLSQIIDDFDPVLLEDKHFEEYIRNDKPVSVV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.*:*::*::*:. .: *: :* . :*** :: ***. :* * .*: ::..** **.** ***. *** *:::* ::**::*.*:** .:**:.***::* . *: . : *: :.** ***:***:*: :.:.*** :*******: **::*: :: *. *::.* .::*:* ::** :*.::: :* *:.** ..** *:: ::* : . *:*:**::: .* ** * :*:*:* * *: *: . *. . * .. *:***.:** *** :* : : :* : ***:**.***:**.*.***:.::.* :::* *: . *::: : : * :*:* **. * :*:*******:*.* :* :: :*** :** ::. : : : ::::: . :*** :.. . :* **: :: :***:** *. .** : * .:: . : .. : :* ::: : :*:.::*:*:. *:* :.:.*: *:*** **:...* ** :: : :****:**: : . * ****** :: * . ..***. *. *:*** : :: .* .*:*.: * .. *:** :: .* * ::.:* .: :: :*:***: : *.. .** * ***:..***.: . :*.::: :*:***.*: *:*: .: . :.* ::.: :* .*:*: :*::. * : : :*. * ** :.. : ***: * . ... .:: :. : :: .* :**::: *.* *: .* :: . ** :*:: : :** : * : : : .: **: : .* .:* : .. . : :.****:****.* *:.: : . *:: * **::*:*:***. ::. : * :** : :: * : . * ..*: : ::: . ** * **.: * * . . :* :. : . .: : : *:: * * : . : . :. : . :.*:::.. . : : . .*. : : :.*: *: : : : . * :*::.*::.* .*: * :: : . .. .* *: ::* ** :** : . : : ..: :***:*::*: .. : ::.:****:**::*:* : .. ::.:**:*::* : *:*:*.:: .:*: ::*::*..*::*:*::** ** *.**::.: :: *: :***:*:**:* *** :**: **** .: :*: :* **:* :.***::*** : .* *.**::*****:**** **:***. *:******:*:::: :*:. ***: :**.:* *:.: . : *: .* * : ** .** ::*.***.: *******:::* : .: : : :*:: *******:**: *: **.: ::*:* *: ..** : *: * .* :.* :::: * *: : :. ***:*:** **:* ::.: . : * ** .* ** :* *. *: *: ***:****** **:***:***.**** *:*. . ** *:******:.*:: : : :.*** **: **:: :* :* :::*:*:*** .:: :: :*:*:** :. ::* ::*:****..*::* ***. ::::. :::*:**: *: : . . . . ::: :** . * * * ** . . :.: * . :: : *: : .**:* :: :. *: ::::**: .. . :. : : . : :: : :: : : * *: : : : : *::. : ** : : : :: :** * *:* . . . ", "identical_positions": 565, "similar_positions": 722, "identity": "20.78%" }, { "cls_id": "homologset.agr.RGD:620666", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70236-1", "uniprot_id": "MP2K6_MOUSE", "id": "P70236-1", "name": "Dual specificity mitogen-activated protein kinase kinase 6", "aln": "--------------------------MSQSKGKKRNP-GLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSKERPTYPELMQHPFFTVHESKAADVASFVKLILGD-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M3C5-1", "uniprot_id": "A0ABK0M3C5_RAT", "id": "A0ABK0M3C5-1", "name": "mitogen-activated protein kinase kinase", "aln": "-------------------------MHRDLKGKKRNP-GLKIPREAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSKERPTYPELMQHPFFTVHEAKAADVASFVKLILGD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52564-1", "uniprot_id": "MP2K6_HUMAN", "id": "P52564-1", "name": "Dual specificity mitogen-activated protein kinase kinase 6", "aln": "--------------------------MSQSKGKKRNP-GLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DGE0-1", "uniprot_id": "MP2K6_DANRE", "id": "Q9DGE0-1", "name": "Dual specificity mitogen-activated protein kinase kinase 6", "aln": "MEGGSDKESKVFCDSPSPNPKGEMSVPSNVRGKKKLPKELKLPKEVFEKPAPAPTPPRDLDSKAYVTIGEKNFVVKADDLEQIGELGRGAYGVVDKMRHVPSGVIMAVKRIRATVNTQEQKRLLMDLDISMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYKQVHEKGKTIPEDILGKITVSIVKALEHLHSNLSVIHRDVKPSNVLINMQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPETNQKGYNVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADRFSADFVDFTSQCLRKNSTERPTYTELMQHPFFTLHDSKDTDVASFVKTILGD-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O62602-1", "uniprot_id": "O62602_DROME", "id": "O62602-1", "name": "mitogen-activated protein kinase kinase", "aln": "----------------------------MSKRHRLTP--FTIAKE----PEAAIVPPRNLDSRATIQIGDRTFDIDADSLEKICDLGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDISMRSSDCPYTVHFYGAMYREGDVWICMEVMSTSLDKFYPKVFLHDLRMEESVLGKIAMSVVSALHYLHAQLKVIHRDVKPSNILINRAGQVKICDFGISGYLVDSIAKTIDAGCKPYMAPERIDPQGNPAQYDIRSDVWSLGIGMIEMATGRYPYDNWRTPFEQLRQVVEDSPPRLPEGTFSPEFEDFIAVCLQKEYMARPNYEQLLKHSFIVEHLQRNTDISEFVARILDLPDAQPAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * :.:.:* * .: .***:***:* : **::.* :.**.** * :*******:*:**** :. ::***** *** :**:**:****:***: ** :** ****::**********:*.******* :* :. : *.:****::*:*.**.:**::*.**********:*** ****:************:***:*************:*: * *.::**:***** ***:* *:***.* ***:**:****:..*:** . **.:* ** : **:*: **.* :*::*.*:. * : :*::.** **. ", "identical_positions": 184, "similar_positions": 90, "identity": "50.0%" }, { "cls_id": "homologset.agr.RGD:620667", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43346-1", "uniprot_id": "DCK_MOUSE", "id": "P43346-1", "name": "Deoxycytidine kinase", "aln": "MATPPKRFCPSPSTSSEGTRIKKISIEGNIAAGKSTFVNILKQASEDWEVVPEPVARWCNVQSTQEEFEELTTSQKSGGNVLQMMYEKPERWSFTFQSYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESDCMNETEWTIYQDWHDWMNSQFGQSLELDGIIYLRATPEKCLNRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTSFDYLQEVPVLTLDVNEDFKDKHESLVEKVKEFLSTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48769-1", "uniprot_id": "DCK_RAT", "id": "P48769-1", "name": "Deoxycytidine kinase", "aln": "MATPPKRFCSSPSTSSEGTRIKKISIEGNIAAGKSTFVNILKQVCEDWEVVPEPVARWCNVQSTQDEFEELTTSQKSGGNVLQMMYEKPERWSFIFQSYACLSRIRAQLASLNGSLRDAEKPVLFFERSVYSDRYIFASNLYESDCMNETEWTIYQDWHDWMNSQFGQSLELDGIIYLRATPEKCLNRIYIRGRDEEQGIPLEYLEKLHYKHESWLLHRTLKTNFEYLQEVPILTLDVNLDFKDKEESLVEKVKEFLSTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27707-1", "uniprot_id": "DCK_HUMAN", "id": "P27707-1", "name": "Deoxycytidine kinase", "aln": "MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNVQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* *.* *:***************************** .********************:****** ***.***************** **:****************.*:***************************:******************.**************:****.**:***:***:****************************.*:******:****** ***** ************* ", "identical_positions": 234, "similar_positions": 18, "identity": "90.0%" }, { "cls_id": "homologset.agr.RGD:620668", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z327-1", "uniprot_id": "SYNPO_RAT", "id": "Q9Z327-1", "name": "Synaptopodin", "aln": "MLGTHFPPPPLGPSEGRAAPCTFQIPDGSYRCLALEAEESSSEDGLQGEVRLVDLEE-EGTSKS------RVNHGTPPLSRAPAIIQPSSCCREARGGFQHSDKPSREWDVVQARKVMTASVSSSPVPRVAQKPALGRSTSFTEKDLKEAKERSQRIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESRGQRSPKLSQEALQTGHPSSPIGHAPGLSVNPTSPSKPGSPKHSSSQSPSRGVPGHIMEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNRETQQSSPNPPETEEVPSPAADINQNPSSPNATLTTAASNSHHNQPTADVNQNPPATITP-------VQQNSSETQCSPNGT---LDSKPNTPSADDGQRPVPAEEVRSSILLIDKVSAPPSAASPFSREATPLSSSGPPAADLMSSSLLIGMQPSTLVASAEQEVSGHAAVTTPTKVYSEVHLTLAKPASVVNRTARPFGMQSPGTTSQIEQSPMMGRRHFGEKAWAPPASSMADRSPQPQRHIMARSPMVERRLVGQRSPVVERRPLGNFTPPPTYAETLSTAPVASQVRSPPSYSTLYPSSDPKPPHLKGQVVPANKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGMEDEPFALGAEASNFQQEPIARDRSGPAAAEETVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSGHA-ELARCPSPTMSLPSSWKYTTNAPGGFRVASLSPARTPPASLYHGYLPENGVLRPEPTKQQPHQMRPSLYALSPVKEPAKISSRATSSRASSRTVSPRAASPAKPSSLDLVPNLPRAGLPPSPALPRPSRSSPGLYNAPVQDSLQPTAVSPTYSSDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQVWKPSFCFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CC35-1", "uniprot_id": "SYNPO_MOUSE", "id": "Q8CC35-1", "name": "Synaptopodin", "aln": "MLGAHFPPPPLGASEGRAAPCTFQIPDGSYRCLALEAEESSSEDGLQGEVRLVDLEE-EGTSQS------RANHGTPPLSRAPAIIQPSSCHREARGGFQRSDRPSHDWDVVQARKVMTASGSSSPVPRVAQKPALGRSTSFTENDLKEAKARSQQIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESRGQRSPKLNQEALQTGRPLSPIGHAPGPSVKPTSPSKPGSPKHPSPQSPSRGVAGHIMEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQSRETQQSSPNPPD-TEVPSPAADINQNPSSPNATLTTLASSSHHSQPTADINQNPPAAITP-------VPQNSSQAQCSPNGT---LDSKPGTLCADDGQSPVPAEEVRSSILLIDKVSAPPSAASTFSREATPLSSSGPPAADLMSSSLLIDMQPSTLVAPAEQEVPGHVAVTTPTKVYSEVHLTLAKPASVVNRTARPFGIQSPG-TSQIEQSPMMGRRQFGEKAWAPPASSMADRSPQPQRHIMSRSPMVERRLLGQRSPVLERRPLGNFTPPPTYAETLSTAPVASRVRSPPSYSTLYPSSDPKPSHLKGQVAPANKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDHGEVGMEEEPFALGAEASNFQQEPIARDRASPAAAEEAVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSGHA-ELARCPSPTMSLPSSWKYTTNAPGGFRVASLSPARTPPASLYHGYLPENGVLRPEPTKQQPYQMRPSLYALSPVKEPAKASSRATSSRTPSRTVSPRAASPAKPSSLDLVPNLPRAGLPPSPALPRPSRSSPGLYTAPVQDSLQPTAVSPTYSSDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQVWKPSFCFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3V7-1", "uniprot_id": "SYNPO_HUMAN", "id": "Q8N3V7-1", "name": "Synaptopodin", "aln": "MLGPHLPPPPLAPSEGRPTPCAFQIPDGSYRCLALEAEESSGEEGLQGEVGPTDLEEDEGVSRSGDDSACRVTQGTPQLPKALG-IQPPSCSREEQGASQHDDRASQDWDVVKAGQMMTASPSPGPGPRVAQKPALGRSTSLTEKDLKEAKARSQQIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESHGQRGQKPSQESLRV-LPSSLPGHAPGLSLSSTSLPEPGPPRHPSPQSPDRGVPGHSMEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPP-AEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTG--PASKPSTLCAD-GQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVS--------------PRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQVWKPSFCFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "H9XVM9-1", "uniprot_id": "H9XVM9_DROME", "id": "H9XVM9-1", "name": "", "aln": "-MDSTLNIENVN--DPTSIASDLSAENTKADLVSLNEPKTYEPTTIAPDLKMENTKN--SIPSP-------IKPNVNDQTSSASDLTAENTKADHDSLNKPKDFNNQILNIISDIDINIKAQEKITQLKEQELKLIQKQNDLANEIHKQQILAKQLSAQNQLKQNECQSGELDLHSQYQNERGGPTSTLYQEKNIASKQIPVVHNNMNCTVEKKRG--YRPSDLIDPSKRQYLLSLSKKLWQEKKESANVSKTVDLRKIFTPATDAAEILPKNRKLYASSAFYSPT-LHPTVEDQVELARRISHSLSDISN-QTSKGQSMYVNRKKRSDKWVHEGGSQGNDAINPFKENSETKSTMEVAKLEKIPLKLIMNPNGKVRDYNSLKDLINVEAGLLSPDNCAELITALQLHQGRGAELFAKRRRKADNWVVDESHSGTQYHPSGIPDFQQYQQRPVLSPNILPAYSDAGKHRVQLNIHQNQLIEKYSKPGLQVVQSPWKAALQTGSASSAFLEDTKSFSPPALTPIPSSQAGSKDWTDANEPMPHGSSRRNTNAVASSPRSVIVPSNPQRDLAYTPCVAQGWGGRSVELPKDSFQSNESQSSWQTEPHIGRADDSNPSFNNYIFGERLTSNFAFDVQNRLHSLENFQKYFLEYQRLELEILRNRE----SSRVLQHDAYESLLDFTPQNEFKVISGEDLKVNCDLDEKVNVRELIQSFEKQNTTDLRHDAAPIEGLYVPKEISLSSYAAPS-----QQCEIHSKHFERPYEDTFPRTFPRNNYSANNNFPGNDGIGEFP--LSKPTGLTTGTLHQQPYSPTSYKKTVPGLEKVENFARYE-----------QPDRKRLTSGSPQYLNALQNSQVRNASPIPFGTSLNEQTSWPPRSVLLQGGSPSPLPNHVQTFNKCAKGWG--SIPVKQQSYSSQYN-LPGNLPYSDF---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : : : . .. :. : . ::*: :: : :: : :: . . . . .. . : . : . . : . : .* .: :::. .: : . . : : : :...:::: *: .* * : . ..:* ::*..: ::. . * ::. .* .: . : * .:. .*. :: . * . : . *: ..* : : .:. * :* * .:*: :.. ** : . :.: : . :: . :. .*. . : . . :* : . : : . : .**. * . .: * : * :.: . :. : . : .. ..:: .*.: * . . : : :.. . . . : * : * . . ::. *.. . : : : *. * :* ..* .. . .: : .*. . *. . .* :*: :: . . *. * . *... .. : . .:..: : :..* : : * . :: : * : * * . *:: ... : .* * :: * . : .. :. : . :: .: . : : . :* . :. **. :: :..*. * : .. * :. * . .:. . * *. . . . . : *.: * . . :* *:. . .:. ::: : : . ...* : : * .. : :..:* : . .* . ** : ** . : . ::.*. : . : *:*:: : .:: ..* ", "identical_positions": 77, "similar_positions": 337, "identity": "8.11%" }, { "cls_id": "homologset.agr.RGD:620669", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55070-1", "uniprot_id": "DNSL3_MOUSE", "id": "O55070-1", "name": "Deoxyribonuclease gamma", "aln": "MSLHPASPRLASLLLFILALHDTLALRLCSFNVRSFGASKKENHEAMDIIVKIIKRCDLILLMEIKDSSNNICPMLMEKLNGNSRRSTTYNYVISSRLGRNTYKEQYAFVYKEKLVSVKTKYHYHDYQDGDTDVFSREPFVVWFHSPFTAVKDFVIVPLHTTPETSVKEIDELVDVYTDVRSQWKTENFIFMGDFNAGCSYVPKKAWQNIRLRTDPKFVWLIGDQEDTTVKKSTSCAYDRIVLCGQEIVNSVVPRSSGVFDFQKAYDLSEEEALDVSDHFPVEFKLQSSRAFTNNRKSVSLKKRKKGNRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O89107-1", "uniprot_id": "DNSL3_RAT", "id": "O89107-1", "name": "Deoxyribonuclease gamma", "aln": "MSLYPASPYLASLLLFILALHGALSLRLCSFNVRSFGESKKENHNAMDIIVKIIKRCDLILLMEIKDSNNNICPMLMEKLNGNSRRSTTYNYVISSRLGRNTYKEQYAFLYKEKLVSVKAKYLYHDYQDGDTDVFSREPFVVWFQAPFTAAKDFVIVPLHTTPETSVKEIDELADVYTDVRRRWKAENFIFMGDFNAGCSYVPKKAWKNIRLRTDPNFVWLIGDQEDTTVKKSTSCAYDRIVLRGQEIVNSVVPRSSGVFDFQKAYELSEEEALDVSDHFPVEFKLQSSRAFTNSRKSVSLKKKKKGSRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13609-1", "uniprot_id": "DNSL3_HUMAN", "id": "Q13609-1", "name": "Deoxyribonuclease gamma", "aln": "-----MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEIKDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYHYHDYQDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWKAENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRGQEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKTKSKRS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **.***::*::*.:*::*:********* **:*:::***:***:*****:**:******.*.***:****** ****. *********************:********* .* ********:************::*.**.*****:****************.:*****: :**:*********************:********.*****************.******** *****.****:*..********.*:*************************.:***:*:*:.*..**", "identical_positions": 243, "similar_positions": 52, "identity": "78.39%" }, { "cls_id": "homologset.agr.RGD:62067", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PC14-1", "uniprot_id": "RL23_DANRE", "id": "Q6PC14-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPSAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P62830-1", "uniprot_id": "RL23_MOUSE", "id": "P62830-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62829-1", "uniprot_id": "RL23_HUMAN", "id": "P62829-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62832-1", "uniprot_id": "RL23_RAT", "id": "P62832-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48159-1", "uniprot_id": "RL23_DROME", "id": "P48159-1", "name": "Large ribosomal subunit protein uL14", "aln": "MSKRGRGGTAGGKFRISLGLPVGAVMNCADNTGAKNLYVIAVHGIRGRLNRLPAAGVGDMFVATVKKGKPELRKKVMPAVVIRQRKPFRRRDGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNASSIA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX41-1", "uniprot_id": "RL23A_YEAST", "id": "P0CX41-1", "name": "Large ribosomal subunit protein uL14A", "aln": "MS--G-NGAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX42-1", "uniprot_id": "RL23B_YEAST", "id": "P0CX42-1", "name": "Large ribosomal subunit protein uL14B", "aln": "MS--G-NGAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * .*: * ************::*****:**:***:*:*:* .******:*.:***.:************** **:*:** *.:**:****:*********.* *************.*********:***:. :.", "identical_positions": 101, "similar_positions": 28, "identity": "72.14%" }, { "cls_id": "homologset.agr.RGD:620670", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43602-1", "uniprot_id": "DCX_HUMAN", "id": "O43602-1", "name": "Neuronal migration protein doublecortin", "aln": "MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSGNDQDANGTSSSQLSTPKSKQSPISTPTSPGSLRKHK-DLYLPLSLDDSDSLGDSM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88809-1", "uniprot_id": "DCX_MOUSE", "id": "O88809-1", "name": "Neuronal migration protein doublecortin", "aln": "MELDFGHFDERDKASRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSAAAGPKASPTPQKTSAKSPGPMRRSKSPADSGNDQDANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKVDLYLPLSLDDSDSLGDSM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ESI7-1", "uniprot_id": "DCX_RAT", "id": "Q9ESI7-1", "name": "Neuronal migration protein doublecortin", "aln": "MELDFGHFDERDKASRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLLQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSGNDQDANGTSSSQLSTPKSKQSPISTPTSPGSLRKHK-DLYLPLSLDDSDSLGDSM", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************:*********************************************************************************** **************************************************************************************************************************************************************************************:****************************************************************** ******************", "identical_positions": 362, "similar_positions": 2, "identity": "98.91%" }, { "cls_id": "homologset.agr.RGD:620671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88450-1", "uniprot_id": "DEAF1_RAT", "id": "O88450-1", "name": "Deformed epidermal autoregulatory factor 1 homolog", "aln": "MEDSDS-AAKQLGLAEAAAVAAAAAVAAAAAAAAESEAEEPVLSRDEDSEEDADSEAERETRRVTAVAVMAAESGHMDMGTEALPS--PDE-AAAAAAFAEVTTVTVAN-----VGSSADNVFTTSVANAASISGHVLSGRTALQIG--------DSLNTEKATLIVVHTDGSIVETTGLKGPAAPLTPGPQSPPTPLAPGQEKGGTKYNWDP-SVYDSELPVRCRNISGTLYKSRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDDMT------------------LSGPVRLFVPYKRRKKENELPTTPVKK---DSPKNITLLPATAATTFTVTPSGQITTSGALTFDRASTVEATAVISESPAQGDVFAGATVQEAGVQPPCRVGHPEPHYPGYQDSCQIAPFPEAALPTSHPKIVLTSLPALAVPPSTPTKAVSPTVVSGLEMSEHRSWLYLEEMVNSLLNTAQQLKTLFEQAKQASSCREAAVT-------------QARMQVDAERK--------EQSCVNCGREAMSECTGCHKVNYCSTFCQRKDWKDHQHVCGQS-ASVTVQADDVHVEESVIEKVAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1T5-1", "uniprot_id": "DEAF1_MOUSE", "id": "Q9Z1T5-1", "name": "Deformed epidermal autoregulatory factor 1 homolog", "aln": "MEDSDS-AAKQLGLAEAAAVAAAAAVAAAAAAAAESEAEEPVLSRDEDSEEDADSEAERETRRVTAVAVMAAESGHMDMGTEALPS--PDEAAAAAAAFAEVTTVTVAN-----VGSSADNVFTTSVANAASISGHVLSGRTALQIG--------DSLNTEKATLIVVHTDGSIVETTGLKGPAAPLTPGPQSPPTPLAPGQEKGGTKYNWDP-SVYDSELPVRCRNISGTLYKSRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDDMT------------------LSGPVRLFVPYKRRKKENELPTTPVKK---DSPKNITLLPATAATTFTVTPSGQITTSGALTFDRASTVEATAVISESPAQGDVFAGATVQEAGVQPPCRVGHPEPHYPGYQDSCQIAPFPEAALPTSHPKIVLTSLPALAVPPSTPTKAVSPTVVSGLEMSEHRSWLYLEEMVNSLLNTAQQLKTLFEQAKQASSCREAAVT-------------QARMQVDTERK--------EQSCVNCGREAMSECTGCHKVNYCSTFCQRKDWKDHQHVCGQS-ASVTVQADDVHVEESVIEKVAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75398-1", "uniprot_id": "DEAF1_HUMAN", "id": "O75398-1", "name": "Deformed epidermal autoregulatory factor 1 homolog", "aln": "MEDSDS-AAKQLGLAEAAAVAAAAAVAAAAAAAAGGEAEEPVLSRDEDSEEDADSEAERETPRVTAVAVMAAEPGHMDMGAEALPG--PDE-AAAAAAFAEVTTVTVAN-----VGAAADNVFTTSVANAASISGHVLSGRTALQIG--------DSLNTEKATLIVVHTDGSIVETTGLKGPAAPLTPGPQSPPTPLAPGQEKGGTKYNWDP-SVYDSELPVRCRNISGTLYKNRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDDMT------------------LSGPVRLFVPYKRRKKENELPTTPVKK---DSPKNITLLPATAATTFTVTPSGQITTSGALTFDRASTVEATAVISESPAQGDVFAGATVQEASVQPPCRASHPEPHYPGYQDSCQIAPFPEAALPTSHPKIVLTSLPALAVPPPTPTKAAPPALVNGLELSEPRSWLYLEEMVNSLLNTAQQLKTLFEQAKHASTYREAATN-------------QAKIHADAERK--------EQSCVNCGREAMSECTGCHKVNYCSTFCQRKDWKDHQHICGQS-AAVTVQADEVHVAESVMEKVTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLH6-1", "uniprot_id": "A0A8M2BLH6_DANRE", "id": "A0A8M2BLH6-1", "name": "", "aln": "MDATEEPATKELELGDASESASTG---------------EPVGS-------DTESEAEVAT-----MTVMG-EAGTIDI-TESLPN--PDD---AETAFAEVTAVTVGD-----VQSSDDSVFTSAVATATSIPEHVLTGRATLQIG--------NTLSTQKATLIVVHTDGSIVDATSLKATGTPMTPGPQTPNTPLASGHDKDVSKYNWDP-SVYDNELPVRCRNTSGLLYKNRLGSGGKGRCIKHNNSWYTPTEFEGMSGRASSKDWKRSIRYAGRPLQCLIQERILNPHAASCTCAACCDDLSTVSDTCTKEGSYGQESLSMTGPVRLFVPYKRRKKDNERAASPDNKKEIQSPKNITLAPG---ATFTVSPSGQISTSGTLSFDRSASGETASIISDSPAAPDVYTNTTVLTT-------------------------------LP------ALAVVPQQAVVQSKPPPAG--TLLNGLETGEQRTWLYLEEMANTLLSNVQQLKVLIAQAKQASQSGAHATISPDKNSSGRKESFQSQFSLTEEPEGKITEIIIKHTCVNCGREASCECTGCHKVHYCSGFCQRKDWKEHQLNCCQPNTSVSIQED----TQMELDKGKA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24180-1", "uniprot_id": "DEAF1_DROME", "id": "Q24180-1", "name": "Deformed epidermal autoregulatory factor 1", "aln": "MEQVDSSTELHLNRKDLAALAEDVVKEEVILESSSHHHHHHHHQLDTKVRMVTSSSNDNSGSGGASGGTSGAGGGNGGGGVVSVPVSLPIGSMITGTTFNVITPDQLPPHFKPMLCVDNNGYLSGSTVSMGNDLKTIVIQQQQTQPGGGGGGANNAGTNTTATNTIGLNHDGSGSNNSHDSLATLEHAAGGASGVGGGGGGTGGGSSGWSENPSTQHNEVFQIRCKTTCAELYRSKLGSGGRGRCVKYKDKWHTPSEFEHVCGRGSSKDWKRSIKYGGKSLQSLIDEGTLTPHATNCSCTVCCDDEAG---------------ESASGPVRLFTPYKRRKRNQTDLDMESGP---KRKRNTHHSNNNNSNTNNNNTSGSGANN-CVDVTAAVAAATASVVDEN----NMFLSEENITSKDEPWAALNDSLDTSTELVDQSQMG----NTYERETFVVNINDGSSIAVLDTSQSMKNIEHVYCTMVKATNDFKRMLNDMKQSFERRIEVLQKERDAAVSAMRVQVHADID------------DPNISGSLHGN----EIISAKKCANCNREALAECSLCRKTPYCSEFCQRKDWNAHQVECTRNPQTTTQQVMLLIDDQS-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :. : .* : : * . . :.*. : . . * . . ::* * : ::* :*. : : :. :: :... . :: : * * .* :. * :: *** : : . . :.* : . * . : :. :* : ::. : :**:. .. **:.:*****:***:* :.*::*:*** :.**.*********:*.*:.**.**:: *.***:.*:*:.**** : :******.******::: . :* * . ..**. :.. : . : : :::::.:. ::: . : : . ** .. . : : . *::* ::: : *: * * * :..: . : :.*.**.*** .**: *:*. *** *******: ** * : :.: * : ", "identical_positions": 112, "similar_positions": 159, "identity": "17.89%" }, { "cls_id": "homologset.agr.RGD:620672", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0R3-1", "uniprot_id": "APEL_RAT", "id": "Q9R0R3-1", "name": "Apelin", "aln": "MNLSFCVQALLLLWLSLTAVCGVPLMLPPDGKGLEE-GNMRYLVKPRTSRTGPGAWQGGRRKFRRQRPRLSHKGPMPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0R4-1", "uniprot_id": "APEL_MOUSE", "id": "Q9R0R4-1", "name": "Apelin", "aln": "MNLRLCVQALLLLWLSLTAVCGVPLMLPPDGTGLEE-GSMRYLVKPRTSRTGPGAWQGGRRKFRRQRPRLSHKGPMPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULZ1-1", "uniprot_id": "APEL_HUMAN", "id": "Q9ULZ1-1", "name": "Apelin", "aln": "MNLRLCVQALLLLWLSLTAVCGGSLMPLPDGNGLED-GNVRHLVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4TTN8-1", "uniprot_id": "APEL_DANRE", "id": "Q4TTN8-1", "name": "Apelin", "aln": "MNVKILTLVIVLVVSLLCSASAGPMASTEHSKEIEEVGSMRTPLRQNPARAGRSQRPAGWRR-RRPRPRLSHKGPMPF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: : . .::*: * :... .: ... :*: *.:* :: . :* * . .* *: ** ************", "identical_positions": 25, "similar_positions": 27, "identity": "32.05%" }, { "cls_id": "homologset.agr.RGD:620673", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96SI9-1", "uniprot_id": "STRBP_HUMAN", "id": "Q96SI9-1", "name": "Spermatid perinuclear RNA-binding protein", "aln": "----------------------------MRSIRSFANDDRHVMVKHS------------TIYPSPEELEAVQNMVSTVECALKHVSDWLDET--------NKGTKTEGETEVKKDEAGENYSKDQG--------GRTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDKPTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDELE----KKDGENVSMKDPPDLLDRQK-----CLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLELICEKS--------IGTCNRPLGAGEALRRVMECLAS--GILLPGGPGLHDPCERDPTDALSY---------MTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSK--PFQKYSWSVTDKEGAGSSALKRPFEDGLGDDKDPNKKMKRNLRK-ILDSKAID---LMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYEASG--PSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGP----------ILTAS-GKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNK--KVAKASAALAALEKLFSGPNAANNKKKKIIPQ-------------------AKGVVNTAVSA-----------------------AVQAVRGRGRGTLTRGAFVG---ATAAPGYIAPGYGTPYGYSTAA--PAYG------------------------LPKRMVLLP--VMKFPTYPVPHYSFF------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91WM1-1", "uniprot_id": "STRBP_MOUSE", "id": "Q91WM1-1", "name": "Spermatid perinuclear RNA-binding protein", "aln": "----------------------------MRSIRSFANDDRHVMVKHS------------TIYPSPEELEAVQNMVSTVECALKHVSDWLDET--------NKGTKPEGETEVKKDEAVENYSKDQG--------GRTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDKPTETLLNTVKDNLPIQIQKLTEEKYQVEQCINEASIIIRNTKEPTLTLKVILTSPLIRDELE----KKDGENVMMKDPPDLLDRQK-----CLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLELICEKS--------IGTCNRPLGAGEALRRVMECLAS--GILLPGGPGLHDPCERDPTDALSY---------MTTQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSK--PFQKYSWSVTDKEGAGSSALKRPFEDGLGDDKDPNKKMKRNLRK-ILDSKAID---LMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYEASG--PSKKTAKLHVAVKVLQAMGYPTGFDADIECISSDEKSDNESKNDTVSSNSSNNTGNSTTETSSTLEVRTQGP----------ILTAS-GKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNK--KVAKASAALAALEKLFSGPNAANNKKKKIIPQ-------------------AKGVVNTAVSA-----------------------AVQAVRGRGRGTLTRGAFVG---ATAAPGYIAPGYGTPYGYSTAA--PAYG------------------------LPKRMVLLP--VMKFPTYPVPHYSFF------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JKU6-1", "uniprot_id": "STRBP_RAT", "id": "Q9JKU6-1", "name": "Spermatid perinuclear RNA-binding protein", "aln": "----------------------------MRSIRSFANDDRHVMVKHS------------TIYPSPEELEAVQNMVSTVECALKHVSDWLDET--------NKGTKPEGETEVKKDDAVENYSKDQG--------GRTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDKPTETLLNTVKDNLPIQIQKLTEEKYQVEQCINEASIIIRNTKEPTLTLKVILHSPLIRDELE----KKDGENVMMKDPPDLLDRQK-----CLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAPLKGWPLELICEKS--------IGTCNRPLGXGEALRRVMECLAS--GILLPGGPGLHDPCERDPTDALSY---------MTTQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSK--PFQKYSWSVTDKEGAGSSALKRPFEDGLGDDKDPNKRMKRNLRK-ILDSKAID---LMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTYEASG--PSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSDNESKNDTVSSNSSNNTGNCTTETSSTLEVRTQGP----------ILSSQQVAKILCGANEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNK--KVAKEVQR--TLEKLFSGPNAANNKKKKIIPQ-------------------AKGVVNTAVSD-----------------------AVQAVRGRGRGTLTRGAFVG---ATAAPGYIAPGYGTPYGYSTAS--PAYG------------------------LPKRMVLLP--VMKFPTYPVPHYSFF------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B247-1", "uniprot_id": "A0A8M2B247_DANRE", "id": "A0A8M2B247-1", "name": "Spermatid perinuclear RNA-binding protein", "aln": "----------------------------MRSIRSFGNDDRHVMAKHS------------TIYPSSEDLEAVQSLVSTVECALKHVSDWMDQSQASQSNPTNASSTQEEETEPTVDESPEGSTNEESSCSSGPSEGGVLCGVMRIGLVAKGLLIKDDMDLELVLMCRENPTKTLLSTVCEHLPQQIEKLTEEKYEVQQCIPEAAILVCTTTEPKLTLKVTLTSPQFKDDCE----TEEQESVESSEPADLLDRQR-----CLVALASLRHAKWFQARVNGLKSCVIVLRILRHMCNRVPAWEPLKGWPLELICEKA--------IATCNRPLGAGEALRRVMECLAS--GILLPGGPGLHDPCEKEPTNTLSA---------MTDEEAEAITSNAQHALRLMAFGQIYKVLDMDPLPSSK--PSQKYPWS--DKEGLG---LKRPYEDGLMDDKDLIKKMKRNLRKAVLDSKAIDSNQPMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTVYEASG--SSKKTAKLHVAVKVLQAMGYPTGFDTDLDSMSADEKSDGEGKSES-STHSSNNT-THSSDSSNTLEVRTQGP----------ILTAS-GKNPVMELNEKRRGLKYELISESGGSHDKRFVMEVEVDGQKFRGAGPNK--KVAKASAALAALEKLFSGPNAAGNKKKKIIPQ-------------------SKGALAAAAAVSAV--------------------AVQAARGRGRPTLTRGAFVS---AAAAPGYVTPGFGAPYGYSAAAATPAYGGL----------------------FIDNPFYQPRTIAPFFIHLGPQDLFSDF----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BI3-1", "uniprot_id": "Q86BI3_DROME", "id": "Q86BI3-1", "name": "", "aln": "MANNNYAGFNYGGTQYNTGQVSYPAVTNATYANAAAYQNAAVAAGQGGYGGAAGAGAGATSGPGAGGYGGYGDYRSAMQYDATKTFYQQSPASYNASGSTASVSKTHYSAPPVKNQVKGKMDKSNGG-----PKPPSSAPPAGNNYSGYDTALYNAASMYVAQQHQGNPNQKPNGGANNWYQRKMGATIPGATAIRGMRPKAPPRPQQLHYCEVCKISCAGPQTYREHLEGQKHKKREASLKMSASANSATQNRGNNYHCELCDVTCTGTDAYAAHVRGAK-HQKVVKLHQKLGKPIPSEEPKKMGKINFVPAAAGGAGVAKTEGGANESDAAGDLDDNLDDSLGENTDNIKPVGGEYIEEVKDEEGKILSFNCKLCDCKFNDPNAKEMHMKGRRHRLQYKRKVQPDLVVDFKPTPRQRRLAEARANRAMMSSHRGGDDHDGGYWEEQRNRQYNEEYDYNNWMSRSFGGAQRFG--RMGNGPPPHFGMMPGGNVRRPESTDDRHAIARHAEIYPKEEELQTIQRIVSHTERALKLVSDALAEQPSDAGAANKKDKAEKPSEKDGRDNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLLLHGDNAVELVVLCAEKPTSGLLQRVANVLPDKLKEVAGDTQVNYRVEVNAEEAALIVLDESVSVKITLTSPLLRDANPGEAATTDEGEGDSEFLPREPCLRALADLRHAKWFQARATGLQSCVMVIRILRDLCQRVSSWQSLPQWSLELLVEKVISSAGFPISPGDCMRRIMEALSSGFLINGPGLLDPCEKDPTDALLELTKQEREDLTVSAQLFLRYIAFRQIYKVLGMEPLPAMKFPMRPWRVNRKRRRSSGKAGGAPGTETESNDIDETGSDEKVAKKEGVGGTPAST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . :: * . :. * *.. . . *::: .:. . : :. . .: :: :.:. . . . . : : .: :. : :*.:. . . : :: :. :*. : . ::. * .: .: . ..: ::: * . .: :. : *:..* * *::: :.: : :*: * * :::: : . .*.. . *: .: :.*.. . : * * : : : . ** : * . :* *: * *:::.* * .: . : : ... * :*: : : :. : : . .:: :. *. : ** : : ..:. ** . .: . :: *:. *::. ..* :* . : . .:.*...:. :.::* . ...:.* . * : :: .: : :.* .*. : .: :**:.: : . . *:: : :... .: ..:::*: :.* . *: . . . .:: * : : :.*:: * * . . . : . * * ", "identical_positions": 58, "similar_positions": 242, "identity": "6.5%" }, { "cls_id": "homologset.agr.RGD:620674", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQS0-1", "uniprot_id": "TALDO_RAT", "id": "Q9EQS0-1", "name": "Transaldolase", "aln": "MSGSPVKRQRMES-ALDQLKQF-TTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRIIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDSSKLAPTLSVKAAQTSDLEKIH--LDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERMFSAENGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q93092-1", "uniprot_id": "TALDO_MOUSE", "id": "Q93092-1", "name": "Transaldolase", "aln": "MSGSPVKRQRMES-ALDQLKQF-TTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGVGKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDNSKLAPALSVKAAQTSDSEKIH--LDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERMFSAENGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37837-1", "uniprot_id": "TALDO_HUMAN", "id": "P37837-1", "name": "Transaldolase", "aln": "MSSSPVKRQRMES-ALDQLKQF-TTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGRKLGGSQEDQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPLEDPGVKSVTKIYNYYKKFSYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLQDNAKLVPVLSAKAAQASDLEKIH--LDEKSFRWLHNEDQMAVEKLSDGIRKFAADAVKLERMLTERMFNAENGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1G0-1", "uniprot_id": "TALDO_DROME", "id": "Q9W1G0-1", "name": "Probable transaldolase", "aln": "MGSDRTLKKQKMS-VLQELKKI-TTIVADTGDFEAINIYKPTDATTNPSLILSASSMERYQPLVQKAVEYAKGKKGSVSEQVAEAMDYLCVLFGTEILKVVPGRVSTEIDARLSFDTKKSVEKALKLIALYKSLGVDKERILIKLASTWEGIKAAEILENEHGVHCNLTLLFSFAQAVACAEAGVTLISPFVGRILDWYVANTDTKKFEALKDPGVISVTNIYNYYKKFGYKTLVMGASFRNVGEIKALAGCDLLTISPALLKELENETESVVTYLSVSNAKLQDIEKIT--VDESRFRWLLNEDAMATDKLSEGIRKFAVDTVKLENLIKTYLK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53228-1", "uniprot_id": "TAL2_YEAST", "id": "P53228-1", "name": "Transaldolase NQM1", "aln": "MSEPSEKKQKVATSSLEQLKKAGTHVVADSGDFEAISKYEPQDSTTNPSLILAASKLEKYARFIDAAVEYGRKHGKTDHEKIENAMDKILVEFGTQILKVVPGRVSTEVDARLSFDKKATVKKALHIIKLYKDAGVPKERVLIKIASTWEGIQAARELEVKHGIHCNMTLLFSFTQAVACAEANVTLISPFVGRIMDFYKALSG-KDYTAETDPGVLSVKKIYSYYKRHGYATEVMAASFRNLDELKALAGIDNMTLPLNLLEQLYESTDPIENKLNSESAKEEGVEKVSFINDEPHFRYVLNEDQMATEKLSDGIRKFSADIEALYKLVEEKM-------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P15019-1", "uniprot_id": "TAL1_YEAST", "id": "P15019-1", "name": "Transaldolase", "aln": "MSEPAQKKQKVANNSLEQLKASGTVVVADTGDFGSIAKFQPQDSTTNPSLILAAAKQPTYAKLIDVAVEYGKKHGKTTEEQVENAVDRLLVEFGKEILKIVPGRVSTEVDARLSFDTQATIEKARHIIKLFEQEGVSKERVLIKIASTWEGIQAAKELEEKDGIHCNLTLLFSFVQAVACAEAQVTLISPFVGRILDWYKSSTG-KDYKGEADPGVISVKKIYNYYKKYGYKTIVMGASFRSTDEIKNLAGVDYLTISPALLDKLMNSTEPFPRVLDPVSAKKEAGDKISYISDESKFRFDLNEDAMATEKLSEGIRKFSADIVTLFDLIEKKVTA-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ::: . *::** * :***:*** :* ::* *:********:*:. * ::: *: *.: . ::: :*:* : * ** :*** :*******:*******.. : :* ::* *::. *: *:*:***::******:*.. ** :.*:***:******.******** ***********:*:: : :. *.: **** **.:**.***:..* * **.****. .*:* *** * :*:. ** :* :.. . *. *: . :*: ** **: *** **.:***:*****:.* * :: : ", "identical_positions": 148, "similar_positions": 94, "identity": "43.4%" }, { "cls_id": "homologset.agr.RGD:620675", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18653-1", "uniprot_id": "KS6A1_MOUSE", "id": "P18653-1", "name": "Ribosomal protein S6 kinase alpha-1", "aln": "MPLAQLK-----EPWPLMELVPLDPENGQTSGEE-------------------------AGLQPS-----KDEAI----------------------------------------------------------------LKEIS---------------------------------------ITHHVKAGSEKADPSQFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKM---------------------------ERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK----------EAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLM-----------GKDRKETMTLILKAKLG--MPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTPRDSPGIPPSAGAHQLFRGFSFVATGLMEDDGKPR----TTQAPLHSVVQQLHG-----KNLV------FSDGYVVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSKRDPS---------EEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTISKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDK----------LPQSQLSHQDLQ--------LVKGAMAATYSALNSSKPTPQLKPIESSILAQRRVRKLPSTTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63531-1", "uniprot_id": "KS6A1_RAT", "id": "Q63531-1", "name": "Ribosomal protein S6 kinase alpha-1", "aln": "MPLAQLK-----EPWPLMELVPLDPENGQASGEE-------------------------AGLQPS-----KDEGI----------------------------------------------------------------LKEIS---------------------------------------ITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDNGHLYAMKVLKKATLKVRDRVRTKM---------------------------ERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK----------EAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLG--MPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTPRDSPGIPPSAGAHQLFRGFSFVATGLMEDDSKPR----ATQAPLHSVVQQLHG-----KNLV------FSDGYIVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSKRDPS---------EEIEILLRYGQHPNIITLKDVYDDSKHVYLVTELMRGGELLDKILRQKFFSEREASFVLYTISKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGYTPFANGPSDTPEEILTRISSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDK----------LPQSQLSHQDLQ--------LVKGGMAATYSALSSSKPTPQLKPIESSILAQRRVRKLPSTTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15418-1", "uniprot_id": "KS6A1_HUMAN", "id": "Q15418-1", "name": "Ribosomal protein S6 kinase alpha-1", "aln": "MPLAQLK-----EPWPLMELVPLDPENGQTSGEE-------------------------AGLQPS-----KDEGV----------------------------------------------------------------LKEIS---------------------------------------ITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKM---------------------------ERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK----------EAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLG--MPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDDGKPR----APQAPLHSVVQQLHG-----KNLV------FSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPS---------EEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDK----------LPQSQLSHQDLQ--------LVKGAMAATYSALNSSKPTPQLKPIESSILAQRRVRKLPSTTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TB58-1", "uniprot_id": "A0AB32TB58_DANRE", "id": "A0AB32TB58-1", "name": "Ribosomal protein S6 kinase", "aln": "MPLAQLA-----EPWPKMELVQLETENGQSTTEDGVSSSVK-QTNCK-RGVVKNIEVNSAGRTPQTQKQMEDGEE----------------------------------------------------------------IKEIN---------------------------------------ITHVVKEGSEKADASQFELLKVLGQGSFGKVFLVRKVTPPDNNQLYAMKVLRKATLKVRDRVRTKM---------------------------ERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHGLGIIYRDLKPENILLDEEGHIKLTDFGLCK----------EAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHSADWWSFGVLMFEMLTGSLPFQGKDRKETMNLILKARLG--MPQFLSSEAQSLLRALFKRNPTNRLGSGSDGAEEIKRHSFFMTIDWNKLFRREIKPPFKPAVARPDDTFYFDSEFTSRTPKDSPGVPPSAGAHQLFRGFSFVATAMLEEEGKEE----PSKPPPHPVVQQLHG-----KNIL------FSDGYVMKEDIGMGSFSVCKRCIHKVTNTEYAVKVIDKTSTDPT---------EEIEILLRYGQHPNIITLKDVYDNGKQVYLVTELMRGGELLDRILKQKFFSEREASAVLHTITKTVEYLHSQGVVHRDLKPSNILYVDESGNPESLRICDFGFAKQLRADNGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMIAGFTPFANGPEDTPEEILSRIGSGRFTLTGGNWDAVSDAAKDLVSKMLHVDPHQRLTARQVLKHPWIVQRDK----------LPNSQLQHQDAK--------LVKGAMAATYSALKSSQPPPELKPIESSFLAQRRVKKLPSTSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR61-1", "uniprot_id": "Q9VR61_DROME", "id": "Q9VR61-1", "name": "non-specific serine/threonine protein kinase", "aln": "MPLADSQKDLRQQPQQQQQQQHVSSTSSSNNAEQQCSSSGLGLQLRQ-RMQITSSGCSSLAVTPMEHTPTEDDESGGGNSGVTSSVTTVTSSQRRQQLQQVQQQSALQAALEQHHISPTADLDSARKRPTHRTLCPPPELMELSDSESQGGVETGGRREGATGRSAPDLEDTEPLYETENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKDRVRSTN---------------------------ERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSK----------QPLDGSK-TYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKLG--MPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIPAVSR-DDAFYFDVEYTSKSPRDSPGGPISASAHEIFRGFSFVAPVLLEGQCAGSNMCSTSASPLHSIAPIPAAPVGAPRTLPGVLPGNFHAEYNLLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEEVEIMLRYGNHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVAYLHEHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEVLKRQGYDLACDIWSLGVLLYIMLSGRTPFASTPNDSPDVILKRIGSGQIDFTSSRWALISVPAKELLRQMLHIVPENRPTAARILEHDWLREQFAGGVQLTEYAVAPGSQLSLGAQQQQQNHISMALRGAVDATFRAIAIPQAAN-VGPVELSMLAKRRAKDRANLHS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38070-1", "uniprot_id": "YPK3_YEAST", "id": "P38070-1", "name": "Serine/threonine-protein kinase YPK3", "aln": "MIFSLDEELHRVSLDDKKNDIKVDYSSAIYNDINHEQGSSITYEESINHLSVHSNAIPLNGMSPAHRMRRRSSAYSKFPILTPPN------------------------------------------------------TRRFSITG------------------SDAMRTNTNRLSITPQDIISSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVN---TSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWNVDK----------------------------------------YWAKTGANNKPTKSKKKKSGAARTSLFTEHFIFRKIDWKLLESGQ----LQKTTLGPIVPVITD----------------------------------------------------------------------LELAENFDTEFTSMSYEETYTDS------------------------------------------------------KPININSVSKS-----------------------------------PDMFKGFSYKASGSYLEKYF-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: . : :. .. . : . * .. .:. :. : . . : .*: ::***:*::***:**:.: . ***** *:** : : : . . **.**::: *. :*:*.*:*: .****:*::: **:** :*.:. : * *.** **:: .: .** *::******** **::.**: ******.* : : : **: ** ** ***:: :.: .**:* * *: *. :: :. * : : * :* ** :.:*.**:*::. :* . . *: :...* .* .*. .:* . :. : .. .:. :*: .:. . . :: ..* :. ** *: .. *:::* .*. . . . . ", "identical_positions": 105, "similar_positions": 149, "identity": "11.01%" }, { "cls_id": "homologset.agr.RGD:620676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUT3-1", "uniprot_id": "KS6A2_MOUSE", "id": "Q9WUT3-1", "name": "Ribosomal protein S6 kinase alpha-2", "aln": "-----------MELSMKKFTVRR-----------------------------------FFSVYLRKKSRSKSS--------------------------------------------------------------------------------------SLSRLEEEG---------------------------IVKEIDISNHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRSKM---------------------------ERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSK----------EATDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLG--MPQFLSAEAQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVAS---SLVQ----EPSQQDVPKAPIHPIVQQLHGNN-----------IHFTDGYEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPS---------EEIEILLRYGQHPNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPQQRLTAVQVLKHPWIVNR---------------EYLSQNQLSRQDVHL---VKGAMAATYFALNRTPQAPRLEPVLSSSLAQRRGMKRLTSTRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M7N7-1", "uniprot_id": "F1M7N7_RAT", "id": "F1M7N7-1", "name": "Ribosomal protein S6 kinase", "aln": "-----------MELNMKKFTVRR-----------------------------------FFSVYLRKKSRSKSS--------------------------------------------------------------------------------------SLSRLEEEG---------------------------IVKEIDISSHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRSKM---------------------------ERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSK----------EAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLG--MPQFLSAEAQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVAS---SLVQ----EPSQQDVPKAPIHPIVQQLHGNN-----------IHFTDGYEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPS---------EEIEILLRYGQHPNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPQQRLTAVQVLKHPWIVNR---------------EYLSQNQLSRQDVHL---VKGAMAATYFALNRTPQAPRLEPVLSSSLAQRRGMKRLTSTRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15349-1", "uniprot_id": "KS6A2_HUMAN", "id": "Q15349-1", "name": "Ribosomal protein S6 kinase alpha-2", "aln": "-----------MDLSMKKFAVRR-----------------------------------FFSVYLRRKSRSKSS--------------------------------------------------------------------------------------SLSRLEEEG---------------------------VVKEIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKM---------------------------ERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSK----------EAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLG--MPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVAS---SLIQ----EPSQQDLHKVPVHPIVQQLHGNN-----------IHFTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPS---------EEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNR---------------EYLSPNQLSRQDVHL---VKGAMAATYFALNRTPQAPRLEPVLSSNLAQRRGMKRLTSTRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VR61-1", "uniprot_id": "Q9VR61_DROME", "id": "Q9VR61-1", "name": "non-specific serine/threonine protein kinase", "aln": "-----------MPLADSQKDLRQQPQQQQQQQHVSSTSSSNNAEQQC--------SSSGLGLQLRQRMQITSSGCSSLAVTPMEHTPTEDDESGGGNSGVTSSVTTVTSSQRRQQLQQVQQQSALQAALEQHHISPTADLDSARKRPTHRTLCPPPELMELSDSESQGGVETGGRREGATGRSAPDLEDTEPLYETENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKDRVRSTN---------------------------ERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSK----------QPLDGSK-TYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKLG--MPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIPAVSR-DDAFYFDVEYTSKSPRDSPGGPISASAHEIFRGFSFVAP---VLLEGQCAGSNMCSTSASPLHSIAPIPAAPVGAPRTLPGVLPGNFHAEYNLLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEEVEIMLRYGNHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVAYLHEHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEVLKRQGYDLACDIWSLGVLLYIMLSGRTPFASTPNDSPDVILKRIGSGQIDFTSSRWALISVPAKELLRQMLHIVPENRPTAARILEHDWLREQFAGGVQLTEYAVAPGSQLSLGAQQQQQNHISMALRGAVDATFRAIA-IPQAANVGPVELSMLAKRRAKDRANLHS-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38070-1", "uniprot_id": "YPK3_YEAST", "id": "P38070-1", "name": "Serine/threonine-protein kinase YPK3", "aln": "MIFSLDEELHRVSLDDKKNDIKVDYSSAIYNDINHEQGSSITYEESINHLSVHSNAIPLNGMSPAHRMRRRSSAYSKFPILTPPN----------------------------------------------------------------------TRRFSITGSDAMRTNTN--------------------RLSITPQDIISSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVN---TSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWNVDKY---------------WAKTGAN-------------------NKPTKSKKKKSGAARTSLFTEHFIFRKIDWKLLESGQ----------LQKTTLGPIVPVITDLELAEN---------------------------------------------------------------------------------------------------------------------------------------------FDTEFTSMSYEETYTDSKPININSVSKSPDMFKGFSYKASGSYLEKYF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .: :: .: :: : ** .:: : : :. : *. . : :*: ::***:*::***:**:.: :. ***** *:** : : : . .. **.**::: *. **:*.*:*: .****:*::: **:** :*.:. : * *.** **:: *: .** *::******** **::.**: :******* : : : **: ** ** ***:: :.: .**:*:* *:::**.*. *: *. :: : * : * * :* ** :.:*.**:*::. :* ... * : : .::. .... . . * :** :.: . *: .: * : :.: * . .:.:.: ... : :: . : .* ::. ", "identical_positions": 109, "similar_positions": 152, "identity": "11.17%" }, { "cls_id": "homologset.agr.RGD:620677", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925U2-1", "uniprot_id": "LTC4S_RAT", "id": "Q925U2-1", "name": "Leukotriene C4 synthase", "aln": "MKEETALLATVTLLGVLLQAYFSLQVISARRTFHVSPPLTSGPPEFERVFRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLFYLFARLRYFQGYARSAQHRLDPLYASARALWLLVAMAALGLLVHFLPGTLRAALFRWLQVLLPMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60860-1", "uniprot_id": "LTC4S_MOUSE", "id": "Q60860-1", "name": "Leukotriene C4 synthase", "aln": "MKDEVALLATVTLVGVLLQAYFSLQVISARRAFHVSPPLTSGPPEFERVFRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLFYLFARLRYFQGYARSAQLRLTPLYASARALWLLVAMAALGLLVHFLPGTLRTALFRWLQMLLPMA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16873-1", "uniprot_id": "LTC4S_HUMAN", "id": "Q16873-1", "name": "Leukotriene C4 synthase", "aln": "MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLAHFLPAALRAALLGRLRTLLPWA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*.****:***:*****************:*:******:********:**********************************.***************** ** **************:******.****.:**:**: *: *** *", "identical_positions": 128, "similar_positions": 16, "identity": "85.33%" }, { "cls_id": "homologset.agr.RGD:620679", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VC10-1", "uniprot_id": "OSGI1_MOUSE", "id": "Q8VC10-1", "name": "Oxidative stress-induced growth inhibitor 1", "aln": "MTSWRHDSLGASSSEPLPVVIIGNGPSGICLSYLLSGHIPYVKPGAVHPHPLLQRKLAEAPGVSILDQDLEYLSEGLEGRSQSPVALLFDALLRPDTDFGGSIDSVLSWKRQKDRAVPHLVLGRNLPGGAWHSIEGSMVTLSQGQWMSLPDLQVKDWMRKKCRGLRNSRATAGDIAHYYRDYVIKKGLSHNFVSGAVVTAVEWAKSEHGSPEVQASSPLFQVNGYLTTKDHGHQPFSLRARNVVLATGTFDSPAMLGIPGETLPFVHHDLSALEAALRAGTVNPTSDPVLIVGAGLSAADAVLFARHYNIQVIHAFRRSVHDPGLVFNQLPKMLYPEYHKVQQMMRDQSILSPSPYEGYRSLPEHQPLLFKEDHQAVFQDPQGGQQLFGVSMVLVLIGSHPDLSYLPRAGADLVIDPDQPLSPKRNPIDVDPFTHESTHQEGLYALGPLAGDNFVRFVQGGALAAASSLLKKETRKPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R430-1", "uniprot_id": "Q8R430_RAT", "id": "Q8R430-1", "name": "Oxidative stress-induced growth inhibitor 1", "aln": "MSSWRHDSLRASSSDPLPVVIIGNGPSGICLSYLLSGYIPYVKPGAVHPHPLLQRKLTEAPGVSILDQDLEYLSEGLEGRSQSPVALLFDALLRPDTDFGGSLDSVLSWKRQKDRAIPHLVLGRNLPGGAWHSIEGSMVTLSQGQWMSLPDLQVKDWMRKKCRGLRNSRATAGDIAHYYRDYVIKKGLSHNFVSGAVVTAVEWAKSEHCSPEAQAPSPLFQVTGYLTAKDHSRQPFSLWAHNVVLATGTFDSPAMLGIPGETLPFVHHELSALEAALRAGTVNPTSDPVLIVGAGLSAADAVLFARHYNIQVIHAFRRSVHDPGLVFNQLPKMLYPEYHKVQQMMRDQSILSPSPYEGYRSLPEHQPLLFKEDRQAVFQDPQGGQQLFGVSMVLVLIGSHPDLSYLPRAGADLAIDPSQPLSPKRNPIDVDPFTHESTQQEGLYALGPLAGDNFVRFVQGGALAAASSLLKKETRKPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UJX0-1", "uniprot_id": "OSGI1_HUMAN", "id": "Q9UJX0-1", "name": "Oxidative stress-induced growth inhibitor 1", "aln": "MSSSRKDHLGASSSEPLPVIIVGNGPSGICLSYLLSGYTPYTKPDAIHPHPLLQRKLTEAPGVSILDQDLDYLSEGLEGRSQSPVALLFDALLRPDTDFGGNMKSVLTWKHRKEHAIPHVVLGRNLPGGAWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKRRGLRNSRATAGDIAHYYRDYVVKKGLGHNFVSGAVVTAVEWGTPDPSSCGAQDSSPLFQVSGFLT-RNQAQQPFSLWARNVVLATGTFDSPARLGIPGEALPFIHHELSALEAATRVGAVTPASDPVLIIGAGLSAADAVLYARHYNIPVIHAFRRAVDDPGLVFNQLPKMLYPEYHKVHQMMREQSILSPSPYEGYRSLPRHQLLCFKEDCQAVFQDLEGVEKVFGVSLVLVLIGSHPDLSFLPGAGADFAVDPDQPLSAKRNPIDVDPFTYQSTRQEGLYAMGPLAGDNFVRFVQGGALAVASSLLRKETRKPP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* *:* * ****:****:*:***************: **.**.*:**********:************:******************************.:.***:**::*::*:**:******************* *******.****:*****:** *********************:****.**************...: * .* .******.*:** :::.:***** *:************* ******:***:**:******* *.*:*.*:******:***********:****** *******:*.********************:****:****************.** * **** ****** :* :::****:************:** ****:.:**.****.***********::**:******:******************.*****:*******", "identical_positions": 385, "similar_positions": 71, "identity": "80.54%" }, { "cls_id": "homologset.agr.RGD:62068", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F9Z5-1", "uniprot_id": "F7F9Z5_RAT", "id": "F7F9Z5-1", "name": "Receptor-type tyrosine-protein phosphatase O", "aln": "MGHLPRERRGGRRLLPLLGLFVLLKIVSTFHVTVRDDNNIVVSLEASDVVSPTSVYVVRVAGESKNYFFEFEESNGTLPPPVVFKATYHGLYYIISLVVVSGNVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGKDFRTMLYKDFLKGKTVFNHWLPGICYSNITFQLVSEATFNKSTLVECSGVSHEPKQHRTAPYPPRNISVRFVNLNKNNWEEPSGSFPEDSFIKP-QDAIGRDRPFHFPEETPETPASNASSG---------WPDPNGTEYESTSQPYWWDSASAAPENEEDFVSVLPADYDTEATLGRTEKPTADPFSAFPVQMTLSWLPPKPPTAFDGFNILIEREGNFTDYLTVDEEAHEFVAELKEPGKYRLSVTTFSSSGACETRKSQSAKSLSFYISPTGEWIEELTEKPQHVSVHVLSSTTALLSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPTTMTSEWTTYYEIAATVSLTSSVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRRKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVLCQKLGSGHDGKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEVNPNVVVISVLAILSILLIGLLLVTLVILRKKHLQMARECGAGTFVNFASLEREGKLPYSWRRSVFTFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSRIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMVSEEEQEDWASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVYTVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLKKKQQFCISDVIYENVSKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q612-1", "uniprot_id": "PTPRO_MOUSE", "id": "E9Q612-1", "name": "Receptor-type tyrosine-protein phosphatase O", "aln": "MGHLPRGTLGGRRLLPLLGLFVLLKIVTTFHVAVQDDNNIVVSLEASDIVSPASVYVVRVAGESKNYFFEFEEFNSTLPPPVVFKATYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFNHWLPGLCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRFVNLNKNNWEEPSGSFPEDSFIKPPQDSIGRDRRFHFPEETPETPPSNVSSGSPPSNVSSAWPDPNSTDYESTSQPFWWDSASAAPENEEDFVSALPADYDTETTLDRTEKPTADPFSAFPVQMTLSWLPPKPPTAFDGFNILIEREENFTDYLTVDEEAHEFVAELKEPGKYKLSVTTFSSSGACETRKSQSAKSLSFYISPTGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPILGVFRKYVVEMFYFNPTTMTSEWTTYYEIAATVSLTASVRIASLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSLPRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQLGSGHNGKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDTPSVPTFIAVSTMVTEVNPNVVVISVLAILSTLLIGLLLVTLVILRKKHLQMARECGAGTFVNFASLEREGKLPYSWRRSVFALLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSHIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMVSEEEEEDWASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFTVRQQAAKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLRKKQQFCISDVIYENVSKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16827-1", "uniprot_id": "PTPRO_HUMAN", "id": "Q16827-1", "name": "Receptor-type tyrosine-protein phosphatase O", "aln": "MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISPASVYVVKITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFNHWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNWEEQSGNFPEESFMRS-QDTIGKEKLFHFTEETPEIPSGNISSG---------WPDFNSSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTAFDGFHIHIEREENFTEYLMVDEEAHEFVAELKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** *.******* ****:* .::***:*:*************::**:*****:::************ *.******:***:********:****.*************************************************:*********:**********:************:********************** *****************:*****:********** **.***:**::. **:**::: ***.***** *..* *** *** *.::**:****:**********.*::***.** :*:.::**..***.*:..** ***** *:*************:* **** ***:** ******************:**********:******************:*************************:*******************************************:*************:******************************************** ****************:*******************:*****.********************************************************** ******************::**************************************: **************************************:**::**.:. **********************************:***************:************** **********:**************************:*****.****:*::*****************************************:*********************************************************************************************************:************************************:****::***.********** *****************.***********. *****:**********************************************************************::******************", "identical_positions": 1094, "similar_positions": 96, "identity": "89.23%" }, { "cls_id": "homologset.agr.RGD:620680", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NF01-1", "uniprot_id": "P121B_HUMAN", "id": "A6NF01-1", "name": "Putative nuclear envelope pore membrane protein POM 121B", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRRVRTS--------------------------------ELWKRNGPSSSPFSSPASSRSQTPERPAKKIREEEMCHHSSSSTPLAADKESQGEKAADTTPRKKQN-SNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPPTTLLGLIPAPSMVPATDTKAPPTLQAETTTKPQATSAPSPAPKQSFLFGTQN--TSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPF-FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG-APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATS--APATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPA--AAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFG-LKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATT------QTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAPFGSAAPSFSIGAGSKTLGARQRLQARRQHTRKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8CG34-1", "uniprot_id": "P121C_HUMAN", "id": "A8CG34-1", "name": "Nuclear envelope pore membrane protein POM 121C", "aln": "MSPAAAAAGAGERRRPIASVRDGRG--RGCGGPAGAALLGLSLVGLLLYLVPAAAALAWLAVGTTAAWWGLSREPRGSRPLSSFVQKARHR-------------RTLFASP-PAKSTANGNLLEPRTLLEGPDPAELLLMGSYLGKPGPPQPAPAPEGQDLRNRPGRRPPARPAPR----------STPPSQPTHRVHHFYPSLPTPLLRPSGRPSPRDRGTLPDRFVITPRRRYPIHQTQYSCPGVLPTVCWNGYHKKAVLSPRNSRMVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQN-SNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN--TSPSSPAAPAASSASPMFKPIFTAPPKSEKEGLTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPF-FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG-APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATS--APATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFG-LKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATT------QTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96HA1-1", "uniprot_id": "P121A_HUMAN", "id": "Q96HA1-1", "name": "Nuclear envelope pore membrane protein POM 121", "aln": "MSPAAAAAGAGERRRPIASVRDGRG--RGCGGPARAVLLGLSLVGLLLYLVPAAAALAWLTVGATAAWWGLSREPRGSRPLSSFVRKARHRRPLSSFVRKARHRRTLFASP-LAKSTANGNLLEPRTLLEGPDPAELLLMGSYLGKPGPPQPAAAPEGQDLRDRPGRRPPARPAPRSPPPRSPPPRSPPPSPPTHRAHHVYPSLPTPLLRPSRRPSPRDCGTLPNRFVITPRRRYPIHQAQYSCLGVLPTVCWNGYHKKAVLSPRNSRMVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKEKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVANGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADRESQGEKAADTTPRKKQN-SNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN--TSPSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPF-FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG-APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLATS--APATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPA--AAPTPAPPSMIKVVPAYVPTPIHPIFGGATHSAFG-LKATASAFGAPASSQPAFGGSTAVF-FGAATSSGFGATT------QTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSTTTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAPFGSAALSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K3Z9-1", "uniprot_id": "PO121_MOUSE", "id": "Q8K3Z9-1", "name": "Nuclear envelope pore membrane protein POM 121", "aln": "MSPAAAAADGGERRRPPLGGREGRSRARGYGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRALSSFVRDARRHP-----------RPALTASPPPAKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALR---QDPRERPGRRPPAR--------------SPPPASAVQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSPRNSRMVCSPVTVRIAPPDSKLFRSSMSEQILDTTLSSPSSNAPDPCAKETVLNALKEK-KKRTVAEEDQLHLDGQENKRRRHDSGGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLASACTGGIPSSSRNAITSSYSSTRGISQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCQQSSSSPPLVTDKESPGEKVTDTTTGKQQSSWTSPPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERKASLQWFNKVLEDKPDDASASATDGPPSTSPPFTFTLPAVGPAASPASLPAPSSNPLLESLKKMQESP-APSSSEPAEAATVAAPSPPKTPSLLAPLVSPLAGP---LASTSSDSKPAATFLGLASASSITPLTDSKSSGVSQAEQSVSTPASTASSPTPKPSMLFGMLSPPASSSSLATPAPACASPMFKPIFPATPKSESDSPLPSSSSAATTASSSTAPPTAASTTP-TFKPIFDKMEPFTAMPLSTPFSLKQTTATATTTATSAPLFTGLGTATSTVASGTAAS-----ASKPVFGFGVTTAAS----TASSTMTSTSQSVLFGGAPPVTTSSSAPALASIFQFGKPLAPAASAAGTSFSQPLASSTQTAASNS--GFSGFGSTLTTSTSAPATTSQPTLTFSNTVTPTFNIPFSSSAKPALPTYPGANSQPTFGATDG----ATKPALAPSFGSSFTFGNSVASAPSAAPAPA------------------TFGSAAQPAFGGLKAAASTFGAPASTQPAFGSTTSVFSFGSATTSGFGAAATAATTTQTTNSGSSSSLFGSSAPSPFTFGGSAAPAGSGGFGLS-ATPGTSSTSGTFSFGSGQSGTPGTTTSFG-SLSQNTLGAPSQGSPFAFSVGSTPESKPVFGGTSTPTFGQSAPAPGVGTTGSSLSFGASSTPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52591-1", "uniprot_id": "PO121_RAT", "id": "P52591-1", "name": "Nuclear envelope pore membrane protein POM 121", "aln": "MSPAAAAADGGERRRPPLGVREGRGRTRGCGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRGLSSFVRESRRHP-----------RPALTASPLPAKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALP---QDPRDRPGRRPPSR--------------SPPSSSTAQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSARNSRMVCSPVTVRIAPPDSKLFRSPMPEQILSTTLSSPSSNAPDPCAKETVLNALKEK-KKRTVAEEDQLHLDGQENKRRRHDSSGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLTSTCTGGIPSSSRNAITSSYSSTRGVSQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCHQSSSSAPLVTDKESPGEKVTDPATGKQQSLWTSPPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERRASLQWFNKVLEDKTDDASTPATDTSPATSPPFTLTLPTVGPAASPASLPAPSSNPLLESLKKMQESP-APSSSEPPEAATVAAPSPPKTPSLLAPLVSPLTGP---LASTSSDSKPTTTFLGLASASSATPLTDTKAPGVSQAQLCVSTPAATAPSPTP-ASTLFGMLSPPASSSSLATPGPACASPMFKPIFPATPKSESDNPLPTSSSAATTTPASTALPTTATATAHTFKPIFESVEPFAAMPLSPPFSLKQTTAPATTAATSAPLLTGLGTATSTVATGTTAS-----ASKPVFGFGVTTAAS----TAS-TIASTSQSILFGGAPPVTASSSAPALASIFQFGKPLAPAASVAGTSFSQSLASSAQTAASNSSGGFSGFGGTLTTSTSAPATTSQPTLTFSNTVTPTFNIPFSASAKPALPTYPGANSQPTFGATDG----ATKPALAPSFGSSFTFGNSVASAPSAAPAPA------------------AFGGAAQPAFGGLKASASTFGTPASTQPAFGSTTSVFSFGSATTSGFGAAA---ATTQTTHSGSSSSLFGSSTPSPFTFGGSAAPAGGGGFGLS-ATPGTGSTSGTFSFGSGQSGTTGTTTSFGGSLSQNTLGAPSQSSPFAFSVGSTPESKPVFGGTSTPTFGQSAPAPGVGTTGSSLSFGAPSTPAQGFVGVGPFGSGAPSFSIGAGSKTPGARQRLQARRQHTRKK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:* *:* :****.**:********************* **** *::****.**.:*:** ***.:*.:. *:*. .* .***********:********:********:***********:*::*******:.****.* ** ..*: .* *.*.**:***:...*:.*:** ***:*********** .* *...*.. ***. * ******.**.** . :** *.*.* **:*.:*:*** .*.* .* **:*:. . **: ... *::*.**:* * *** . :*.** *:*..:.*.*******.*.****.:. *...*.::*:.:*:: **::::*. **:*:*..: * :::**..** :****:.**:.:*:***:***.:***:**. *:** ****.****:.:.:* *:: * :::**..*** ** .:::* :**:.******** * .::.: *:***.* ::. **:*.* .*****.**:** ****:********** ********.:***..**:*****.**:***::* *:****:************.*.* :**:** **.*::.*** ***:**:**:***:*****.:*:** **:**:*****:: **: ******:***::**************.*.**:. ****:.:*:*:****:****:..*:*.* .*.**:**:..*.:****.*.**.*********:***** .:*******:********.*:********.****.* ********** ****************", "identical_positions": 501, "similar_positions": 235, "identity": "39.48%" }, { "cls_id": "homologset.agr.RGD:620681", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0D6-1", "uniprot_id": "TCO2_RAT", "id": "Q9R0D6-1", "name": "Transcobalamin-2", "aln": "---------MELLKALLLLSG--------------VLGALAEFCVIPKMDGQLVEKLGQRLLPWMDRLSSEQLN-------------------------PSIYVGLRLSSMQAGTKENLYLHNLKLH---YQQCLLRSTSSDDNSG-----------------------------------------------------------------------CQTKISGGSLALYLLALRANCELLGS----RKGDRMVSQLKWFLEDEKKAIGHHHEG----HPHTSYYQYGLSILALCVHRKRVHDSVVGKLLYAVEHDYFTYQGHLSVDTEAMAGLAFTCLERFNFNSDLRPRITTAIETVREKILKAQAPEGYFGNIYSTPLALQMLMTSP--GVGLGPACLKARKSLLLSLQDGAFQNPMMISQLLPVLNHKTYLNLISPD-----------------------------CQAPRVMLVPATEDPVHLSEVS-VTLKVSS-VLPPYERTVSVFAGASLEDVLNRARDLG-EFTYGTQASLSGPYLTSVLGKEAGDR--EYWQLLRVPDTP-----------LLQGIADYKPKNGETIELRLVKM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88968-1", "uniprot_id": "TCO2_MOUSE", "id": "O88968-1", "name": "Transcobalamin-2", "aln": "---------MELLKALLLLSG--------------VFGALAEFCVIPRIDSQLVEKLGQRLLPWMDRLSSEQLN-------------------------PSVFVGLRLSSMQAGTKEDLYLHSLKIH---YQQCLLRSTSSDDNSS-----------------------------------------------------------------------CQPKLSGGSLALYLLALRANCEFFGS----RKGDRLISQLKWFLEDEKKAIGHNHEG----HPNTNYYQYGLSILALCVHQKRLHDSVVGKLLYAVEHDYFTYQGHVSVDTEAMAGLALTCLERFNFNSDLRPRITMAIETVREKILKSQAPEGYFGNIYSTPLALQMLMTSPASGVGLGTACIKAGTSLLLSLQDGAFQNPLMISQLLPILNHKTYLDLIFPD-----------------------------CQASRVMLVPAVEDPVHISEVISVTLKVAS-ALSPYEQTFFVFAGSSLEDVLKLAQDGG-GFTYGTQASLSGPYLTSVLGKDAGDR--EYWQLLRAPDTP-----------LLQGIADYKPQDGETIELRLVRW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20062-1", "uniprot_id": "TCO2_HUMAN", "id": "P20062-1", "name": "Transcobalamin-2", "aln": "---------MRHLGAFLFLLG--------------VLGALTEMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLN-------------------------PSIYVGLRLSSLQAGTKEDLYLHSLKLG---YQQCLLGSAFSEDDGD-----------------------------------------------------------------------CQGKPSMGQLALYLLALRANCEFVRG----HKGDRLVSQLKWFLEDEKRAIGHDHKG----HPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYAVEP---FHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVREEILKAQTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPD-----------------------------CLAPRVMLEPAAETIPQTQEIISVTLQVLS-LLPPYRQSISVLAGSTVEDVLKKAHELG-GFTYETQASLSGPYLTSVMGKAAGER--EFWQLLRDPNTP-----------LLQGIADYRPKDGETIELRLVSW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4K2-1", "uniprot_id": "Y3556_DROME", "id": "Q9W4K2-1", "name": "Uncharacterized protein CG3556", "aln": "MLSLSSPPWLLLLVLFFFANGSATVVSLAENVTLATLPSTSPISVSFSTTSSVVAPISTELENQTASSSNLNTNNEASDEQTGNSNSNTSSHSRNINGLPSSNSNIDNANSNSSSVSSLSTTTSAISGVDQQESLILATPTALNGSGTPPEHQTIGQAPPTKGEQEAILRALDWLKEKRASDYGWGNDTHVVILAKELSGGRDPNDSVDGHVQVIQELEDTLSVKEMEIEILAMLDRHHTLPKPLDLDKLARYVLALGSLCKDPKHFHGHDLVATLQHHEPAQDIEFALTTLSACSSAAHVRKRQIRRLLDIASG-----VTDQSVDAIAMVILALRCIVT----DHRHRHLQHFVRRPARGLATLQDQRGSFGSLRSTALAMQALQDLEYDPAGHWNRTAASRYILSRQRADGGWSEEPLQDGQEPDIGVGLTADIILALGWKGLGAVRALQCDHVIRESSDPTENGEPKLAVPFGLSSSAEESDAKNISYTYTLWVGSNVTESFSLSLVSPKNTSFFKAMTQAAEMDPRFIFEAREWPNGHYVHTLYGKKEEPRGYHYWLLYRLPELPDPNNTPGNQLIAPVGVDELMVEDGEHYLYWYKKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::: * .: : : :. . :* :. .* * : * ** .: :. ::.: ..* . : *:.*: :: : :.. : . * .: : :**: . . . * * : * : :* *: **. . * :. ::.* *: * :::. : :** .. . ***: **. **: *: : :: :. . : . * .* **.: **.**:* * . : * . **.:.: : . * :. ::* . * . * .:.* . ** * * .: :. .::. ..:. * : . * : :: .* *: :: ** * .:* * * *: * *: : ::** ", "identical_positions": 72, "similar_positions": 132, "identity": "11.92%" }, { "cls_id": "homologset.agr.RGD:620682", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40630-1", "uniprot_id": "TFAM_MOUSE", "id": "P40630-1", "name": "Transcription factor A, mitochondrial", "aln": "-------MALFRGMWS---------VLKALGRTGVEMCAGCGGR---IPSSISLVCIPKCFSS----------MGSYPKKPMSSYLRFSTEQLPKFKAKHPDAKLSELVRKIAALWRELPEAEKKVYEADFKAEWKAYKEAVSKYKEQLTPSQLMGMEKEARQRRLKKKALVKRRELILLGKPKRPRSAYNIYVS-ESFQEAKDD--SAQGKLKLVNEAWKNLSPEEKQAYIQLAKDDRIRYDNEMKSWEEQMAEVGRSDLIRR------SVKRS-GDISEH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91ZW1-1", "uniprot_id": "TFAM_RAT", "id": "Q91ZW1-1", "name": "Transcription factor A, mitochondrial", "aln": "-------MALFRGMWG---------VLRTLGRTGVEMCAGCGGR---IPSPVSLICIPKCFSS----------LGNYPKKPMSSYLRFSTEQLPKFKAKHPDAKVSELIRKIAAMWRELPEAEKKVYEADFKAEWKVYKEAVSKYKEQLTPSQLMGLEKEARQKRLKKKAQIKRRELILLGKPKRPRSAYNIYVS-ESFQEAKDE--SAQGKLKLVNQAWKNLSHDEKQAYIQLAKDDRIRYDNEMKSWEEQMAEVGRSDLIRR------SVKRPPGDISEN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00059-1", "uniprot_id": "TFAM_HUMAN", "id": "Q00059-1", "name": "Transcription factor A, mitochondrial", "aln": "-------MAFLRSMWG---------VLSALGRSGAELCTGCGSR---LRSPFSFVYLPRWFSSV---------LASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVA-ERFQEAKGD--SPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRR------TIKKQRKYGAEEC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86BR8-1", "uniprot_id": "Q86BR8_DROME", "id": "Q86BR8-1", "name": "", "aln": "MIYTTTLMSSRGGLIGSLINKVRQVVAKDWPPSDPSRANDTDHRPLTPPRPLAAASISNTPAVPSKTLEEQLGLPPRPKKPLTPYFRFMREQRPKLKAANPQITTVEVVRQLSKNWSDADAQLKERLQAEFKRDQQIYVEERTKYDATLTEEQRAEIKQLKQDLVDAKERRQLRKRVKELGRPKKPASAFLRFIASERINTPQGDKQTYREWHQKTTAKWTRLSDSEKEVYMQESRKEMELYRKAISVWEEKMIRLGHIDVVRHGNLIDPPEPKPRKTLASKDI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .: . * :. . . . . * ..: :.. : : ****::.*:** ** * :** :*: . *::*::: * : *: : :: : : * * :::. ** .* ::: : :: ::.: **:**:* **: ::: * :: .:.: : : : .. *..** .**: *:* ::.: * : :. ***:* .:*: *::*: . : :.. ", "identical_positions": 48, "similar_positions": 94, "identity": "16.9%" }, { "cls_id": "homologset.agr.RGD:620683", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23443-1", "uniprot_id": "KS6B1_HUMAN", "id": "P23443-1", "name": "Ribosomal protein S6 kinase beta-1", "aln": "-------------------------MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPE------------CFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTK-------------------------AERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVT----------HTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLN--LPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRG----ASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQP---NSGPYKKQAFPMISKRPEHLRMNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P67999-1", "uniprot_id": "KS6B1_RAT", "id": "P67999-1", "name": "Ribosomal protein S6 kinase beta-1", "aln": "-------------------------MRRRRRRDGFYPAPDFRHREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPE------------CFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTK-------------------------AERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVT----------HTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLN--LPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRG----ASASTANPQTPVEYPMETSGIEQMDVTTSGEASAPLPIRQP---NSGPYKKQAFPMISKRPEHLRMNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BSK8-1", "uniprot_id": "KS6B1_MOUSE", "id": "Q8BSK8-1", "name": "Ribosomal protein S6 kinase beta-1", "aln": "-------------------------MRRRRRRDGFYLAPDFRHREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPE------------CFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTK-------------------------AERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVT----------HTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLN--LPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRG----ASASTANPQTPVEYPMETSGIEQMDVTVSGEASAPLPIRQP---NSGPYKKQAFPMISKRPEHLRMNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7UVV0-1", "uniprot_id": "A0A8N7UVV0_DANRE", "id": "A0A8N7UVV0-1", "name": "Ribosomal protein S6 kinase", "aln": "------------------------------------------------MAGVFDIDLDPPEDNVSDEELSDGAKINEYIDQCSG--FEF-MEDCEKFEISEDSVNQGTEKIRPE------------CFELLRVLGKGGYGKVFQVRKVAGAASGKIFAMKVLKKAMIVRNAKDTAHTK-------------------------AERSILEEVKHPFIVDLIYAFQTGEKLYLILEYLSGGELFMQLEREGIFLEDTACFYLAEISLALGHLHQKGIIYRDLKPENIMLNYNGHVKLTDFGLCKESIHDGTVT----------HTFCGTIEYMAPEILTRSGHNRAVDWWSLGALMYDMLTGAPPFTAENRKKTIDKILKCKLN--LPPYLTQEARDLLKKLLKRNASVRIGASPRDVLDIQRHSFFRHINWDDLLAFKIDPPFKPFLQSADDVSQFDSKFTSQTPVDSPDDTKLSESDNQVFLGFTYIAPSVLENIKEKFTFEPKSRSPRKVLGSPRTPVSPLKAEVEDGWSRGPLFPEVTTSSSLLPPTGALKQASNVEQMDMSSNMEASAPLPIKKPLGSNTGSFMKQPHPVGGRRPKHLKMKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94533-1", "uniprot_id": "Q94533_DROME", "id": "Q94533-1", "name": "Ribosomal protein S6 kinase", "aln": "-------------------------------------MADVSDPSELFDLELHDLELQDDKARDSDDDRIELDDVDLEPELCIN--LHQDTEGQETIQLCEENVNPGKIKLGPK------------DFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTR-------------------------AERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCKEHIQEGIVT----------HTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLN--LPAYLTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFDTRFTRQIPVDSPDDTTLSESANLIFQGFTYVAPSILEDMHRANRMP--ARSPRRTPRQLPDSSFRLQFPS-----------ANVGANAPLAMHGHSQRSGMFARATPPHHMQTFAPRPSPAQ----DEMMDVQGLPMV-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38070-1", "uniprot_id": "YPK3_YEAST", "id": "P38070-1", "name": "Serine/threonine-protein kinase YPK3", "aln": "MIFSLDEELHRVSLDDKKNDIKVDYSSAIYNDINHEQGSSITYEESINHLSVHSNAIPLNGMSPAHRMRRRSSAYSKFPILTPPNTRRFSITGSDAMRTNTNRLSITPQDIISSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVN---TSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWN--------------------VDKYWAKTGANNKPTKSKKKKSGAARTSLFTEHFIFRKIDWKLLESGQLQKTTLGPIVP-VITDLELAENFD--------------------------------------TEFTSMSYEETYTDSKPININSVSKSPDMFKGFSYKAS-----GSYLEKYF--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : :. . . : :. :. .: .. *: :***:*.****: *:.. :.* :*** *:** *: . . * .: ***.**. ::** **.*.*:*: . ****:*:*:.***** :*:..* : * *..** :** ** .** *::******** :*: .**: ******.*: ::. * ::: ** ** ***** ..:.: **:***.*::***.* **:*..*:* *:.* : * . :* **: :*::. *:*:: . * . : : . ** . .. . : : : : * .* ** : : :.* :: .:. : . : . . : . : ", "identical_positions": 115, "similar_positions": 128, "identity": "18.98%" }, { "cls_id": "homologset.agr.RGD:620684", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UMZ2-1", "uniprot_id": "SYNRG_HUMAN", "id": "Q9UMZ2-1", "name": "Synergin gamma", "aln": "MALRPGAGSGGGGAAGAGAGSAGGGGFMFPVAGGIRPPQAGLMPMQQQ---GFPMVSVMQPNMQGIMGMNYSSQMSQGPIAMQAGIPMGPMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKP----------------------------------------------------------------------------------------------------GPSLEEKFLVSCDISTSGQEQIKLN----TSEVGHKALGPG---SSKKYPSLMASNGVAVDGCVSGTTTAEAENTSDQNLS-------IEESGVGVFPSQDPAQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRGVPAMSPDALNQFPAAPIPTLSGFSMTLPTPVSQP-TVIPSGPAGSMPLSLGQP-VMGINLVGPVGGAAAQASSGFIPTYPANQVVKPEEDDFQDFQDASKSGSLDDSFSDFQ-ELPASSKTSNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKGIAADKSSENTVPPGDPGDKYSAFRELEQTAENKPLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPTKDK---TFPPSFPSG----TIQQKQQTQVKNPLNLADLDMFSSVNCSSEKPLSFSAVFSTSKSVST-PQSTGSAATMTALAATKTSSLADDFGEFSLFGEYSG------------LAPVGEQDDFADFMAFSNSSISSEQKPDDKYDALKEEASPVPLTSNVGSTVKGGQNSTAASTKYDVFRQLSLEGSGLGVEDLKDN----TPSGKSD-DDFADFHSSKFSSIN--SDKSLGEKAVAFRHTKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAADIEDLKYAAFGSYSSNFAVSTLTSYDWSDRDDATQGRKLSPFVLSAGSGSPSATSILQKKETSFGSSENITMTSLSKVTTFVSED--ALPETTFPALASFKDTIPQTSEQKEYENRDYKDFTKQDLPTAERSQEATCPSPASSGASQETPNECSDDFGEFQSEKPKISKFDFLVATSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLNEKPALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALNVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRKEEK---------------------------PAEE-----HPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLVLPDLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SV85-1", "uniprot_id": "SYNRG_MOUSE", "id": "Q5SV85-1", "name": "Synergin gamma", "aln": "MALRPGAGASG--AAGAGAGPGGAGSFMFPVAGGMRPPQAGLIPMQQQ---GFPMVSVMQPNMQGMMGMNYSSQMSQGPIAMQAGIPMGPMPAAGVPFLGQPPFLSMRPAGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKNRDDALEAIKGNLDGFSRDAKMHPTPASHPKKQ----------------------------------------------------------------------------------------------------GPSLEEKLLVSCDVSASGQEHIKLN----TPDAGHKAIVPG---SSKNCPGLMAHNRGAVDGCVSGPASAEAEKTSDQTLS-------KEESGVGVFPSQDPAQSRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGRLTKEELYTVLAMVAVTQRGVPAMSPDALSQFPAAPIPTLSGFPMTLPTPVSQP-TAMPSGPTGSMPLTLGQP-IMGINLVGPVGGAAAPTSSGFMPAYPSNQVGKTEEDDFQDFQDASKSGSIDDSFTDFQ-EMPASSKTSNSQHGNSAPSLLIPFPGTKAS--TDKYAVFKGISTDKPSENPASFGESGDKYSAFRELEQTTDSKPLGESFAEFRSTGTDDGFTDFKTADSVSPLEPPTKD----TFPSAFASG----AAQQT-QTQVKTPLNLEDLDMFSSVDCSGEKQVPFSATFSTAKSVSTRPQPAGSAAASAALASTKTSSLADDFGEFNLFGEYSN------------PASAGEQDDFADFMAFGNSSISSEPKASDKYEALREEVSPSPLSS---STVEGAQHPPAAATKYDVFKQLSLEGAGLAMEEFKEN----TSSTKSE-DDFADFHSSKFSSTS--SDKSLGEKAVAFRHAKEDSSSVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAADTEDLSCAAFGSCSSHFTVSTLTSCEWSDRADALQGRKLSPFVLSAGSRSFSATSNLHTKEISFGSSENITMSSLSKGSALASED--ALPETAFPAFASFKDMMPQTTEQKEFESGDFQDFTRQDMPTVDRSQETSCPSPASSVASHETPKEGADDFGEFQSEKSKISKFDFLVANSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSERAALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALDVIKKANDTLNGISSSAVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRKEET---------------------------PAEE-----QPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLLLPDLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HC52-1", "uniprot_id": "A0AC58HC52_DANRE", "id": "A0AC58HC52-1", "name": "", "aln": "MALRP--------------GSGGGGSFMYPVGGGIGPPQ-GMMPMQQQQQQGFPMVQVMQPNMQGMMGMNFGAQMP-GAMPIQGGMAMG-MQTPGMQFMGQPQFMGMRAPGPQFPADIQKQMAEEHQKRLEQQQRMLEEDRKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPSSQSKKPDSSPSHSSVTSHSLPPAFPDDDDEFSDFVQGPVDAFSSFPSPPHPPSSPSLRAAHANQPLETGPGQHPSSTLPHSVPSSLPVSPAIQHSSVISSSQSAFQGPSLEEKMFSSCDLTADKKAQVSFKPRQALSELNPRAQVTAQFHSSTKARNWAQTQDDFHSAFMTGMAPEPLPATQAPPVADNPPIQPTRASGVGAYPQQD-MQPMVPTWLYNDSLIPELFKKVLEFTMTPAGIDTAKLYPILISSGLPREALGQIWALANRTTPGKLTKEELYTVLALIGVAQSGLTVMSLDILSQFPSPPVPNLPAMTMAIPAVLPQHQQPIMTQPPVSMPMPTAAPPVMSMTPN-----PPAQPPATFITNFPPVQATKADDDDFQDFQEAPKAGVGDDSFTDFQGETGGTFPSMTSSSQSSVPAMLTPVSGSSSS-SSDKYAVFKQLSVEQPAEPTPAVSDSGDKYSVFRELEPPSERKPVGEGFADFKSVSADDGFTDFKTADTVSPLDPPDQAKFQPTFPPPFASSQSLSHSQPASLAQPRNPLNMADLDLFT----------TMAPPTSTADSKLNLFPSAPPSLVLPSAVVKPPSMGGDDFGDFALFGSSSSSEVAPTTSAAGRGASTTVQDDFADFMAFGSSRDQRSETSS------REGNSEG-------QTETSQQRHQIGTDKYDVFKQLSLEG-GLAYDDNKESGGGSFSSLKSDNDDFADFQSSKFCTALGASDKSLVDKVAAFKQAKEDSTSVKSLDLPSIGGSSVGKEDSEDALSVQLDMKLSDMGGDLKHVMSDSSLDLPGLSSHQPPAAESDDMKFDPFGTS----TVSSLGSYDWSDKDDLPSGQGKK--LQGGSQGSLPSSAVVQRKETSFGSSENITHTTVAKVTTFPIEDNSSTSESQFEAFADFG-SIEQAGQD---DDDDFGDFASTVSEKSD--------SPPSATEAEGNQGEMTDEFGAFQGDKPKFGKSDFLKASTQAKVKSSEEMIKNELATFDLSVQGSHKRSHSLGEKEIVRSIPSPAPEQPFRDRSNTLNEKPALPIIRDKYKDLTGEVEESERYAYEWQRCLESALQVITTANNTLNGISSSTVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQELLKDISRVWNNLMGFMSLANLTPDESSLDFSSCILRHGIKNAKELACGVCLLNVDSRSKKKDENTFGRLFKRALTKDTRSKLRVGCTVCLQSDSNYPFCQLNKAFNSETDNFKLMYGGHQYHASCANFWINCVEPKPPGLILPDLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99PT0-1", "uniprot_id": "DDX52_RAT", "id": "Q99PT0-1", "name": "Probable ATP-dependent RNA helicase DDX52", "aln": "---------------------MDSYDLFRRLGAGAKFDVKRFSADATR----------FQVGKR-----KFGSDSS--------------ETVKGLDFFGN------------------KKSVSDECGGLQTQQELQNEETTEGGLLERSK--------EPKKKKRKKMTADVPAQEDLDGTIQWTSSVEAKLQDKKAN--------------------------------------------------------------------------------------------------------GEKKLTSEKLEHLRKEKINFFR------NKHKIHVQG--------------------TDLPDPIATFQQLDQEYKIS------------------------------------PRLLQNILDAGFQVPTPIQMQAIPVMLHG---------------------------RELLASAPTGSGKTLAFSIPILMQLKQP-------------------------------------------------------------------------------------------------------------------------------------------------------------TNKGFRALVISPTRELASQIHRELIKISEGTGFR----------------------------------------------------------------------------------------IHMIHKAAIAAKKFGPKSSKKFDILVTTPN-------------------------------------------------------------RLIYLLKQEPPGIDLTSVEWLVVDESDKLFEDGKTG--------------FRDQLASIFLACT----SPKVRRAMFSATFAYDVEQWCKLNLDNIVSVSIG---ARNSAVETVEQELLFVGSETGKLLAMRELVKKGFN---------------------------------------------------------PPVLVFVQSIERAKELFHELIYEGIN----------------------------------------------------------------VDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARG-IDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGN----------------RGKAVTFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTT------------PKYFLEQAKQKKVAG-----------QNSKKKETLKGKS--------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .:: :..* : . : :* . : ::.:: . . *: ::*: *: ..:. :: **.: :*: .. : *:.: :**. ::.: * . : :*** : :. : .. * ** : * .: : ::.: : . :.. . . :: * :::*: : . : *::: . :** . . .:* * *: . . . ** * .. : .: . :: . . . ** . . .. .* :: .. . . .. * :: . :: * . * * :* * : .. :. * . .*:* .* . *:* :.:: .: :* :*.: :::: .* .. . :: * : .:: : . :. . : : . *:. * . * * ..*. : :*: ::.* .:. *: *: *.:: *: . *::*. : : .* :*: * . . : . :.**:: :*:* .: :*: ..* :: **. . ", "identical_positions": 73, "similar_positions": 218, "identity": "4.88%" }, { "cls_id": "homologset.agr.RGD:620685", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYW0-1", "uniprot_id": "AATF_RAT", "id": "Q9QYW0-1", "name": "Protein AATF", "aln": "-----MAELQPLALQLEQLLN-PRPREADPEADPEEATRARVIDRFDEGEE-EEDDLPVSSIRKLAPVSLLDTDKRYSGKTTSRKAWKEDHWDQTLPSSSDNEIPDEGGSEAGDSE--GLEELSED-----VEEDLEDNEIPDEGGSEDGDSEGL-EEEIS------------------EDVEEDLE---------GEDEEDREEDRNSEDDGVVMA--FSGVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQP-DVFPVFKDKGGPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRYLVKGTKPNAESEEISSEDDELVGEKKKQRK-APPKRKLEMEDYPSFMAKRSADFTVYRNRTLQKWHDKTKLASGKLGKGFGAFER---SILTQIDHILMDKERLLRRTQTKR------------SAYRVLGKPEPVPEPVAETLPGEPESLPQVP--------ANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIRKKVDRKASKGRKLRFHVLSKLLSFMAPIDH-TAMNDEARTELYRSLFGQLNRLDADHGQ------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKX4-1", "uniprot_id": "AATF_MOUSE", "id": "Q9JKX4-1", "name": "Protein AATF", "aln": "-----MAAPQPLALQLEQLLN-PRPREADPEADPEEATRARVIDRFDEGEE-EKDDLAVSSIRKLAPVSLLDTDKRYSGKTTSRKAWKEDHWEQALPSSSDNEASDEGGSEDGDSEGLGLEEISED-----VDEDLEDNKISDEGGSEDGDSEGLGLEEFS------------------EDVEEDLE---------GEDEEDREEDRNSEDDGVVAA--FSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQP-DVFPVFKDKGGPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRHIVNGAKPNTESEEISSEDDELVGEKKKQRK-APPKRKLEMEDYPSFMAKRFADFTIYRNHTLQKWHDKTKLASGKLGKGFGAFER---SILTQIDHIMMDKERLLRRTQTKR------------SAYRVLGKPEPVPEPVAETLPGEPETLPQGP--------ANAHLRDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIRKKVDRKASKGRKLRFHVLSKLLSFMAPIDH-TAMSDDARTELFRSLFGQLNPPDADRGK------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY61-1", "uniprot_id": "AATF_HUMAN", "id": "Q9NY61-1", "name": "Protein AATF", "aln": "-----MAGPQPLALQLEQLLN-PRPSEADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMT--FSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQP-DVFPLFKDKGGPEFSSALKNSHKALKALLRSLVGLQEELLFQYPDTRYLVDGTKPNAGSEEISSEDDELVEEKKQQRRRVPAKRKLEMEDYPSFMAKRFADFTVYRNRTLQKWHDKTKLASGKLGKGFGAFER---SILTQIDHILMDKERLLRRTQTKR------------SVYRVLGKPEPAAQPVPESLPGEPEILPQAP--------ANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIHKKVDRKASKGRKLRFHVLSKLLSFMAPIDH-TTMNDDARTELYRSLFGQLHPPDEGHGD------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM95-1", "uniprot_id": "AATF_DROME", "id": "Q9VM95-1", "name": "Protein Aatf", "aln": "MLRKSKKQPQTVAEKVSKLLAHPNESDSAEDSDFDVATGPRLVDFEE--EEYDLPDARSTDFRKRNVKLLSEQSDRYKGKISSRKELDDDEDKDDEQEVSYEESDEDDENLTNFKQKLNAGGAEDSE----EETAAGHSESGEESEEIESNLTDFKKKFEAG------------DFKYDDDEEEDDDSEEEDHSQESEGDDDDSEDDEAEDDAIKPSDVMSKTNHQAEIQKGLAVQNQLRIWERLLELRINTQKFTSKANQLPAP-ETLTKLASESD-ELQSVLNEAQERSSKLLQQLLSLQSALHQQYSEMKKSVKRKQPTEDSG-------------------------PAVKKFGSVLQSNFQQMIGYRNEVLLKWDDRTKLLTPGAGVKRKSLQED-YDIIKKIGSALANREALVEKSQTPK------------NSQAEQQENTPVQR---------------------------------LKHIYDDSDFYHQQLRELIEYKASTS--SNMSEITKQFVELQKLRQKMKKKVDTRASKGRKLRYVVHNKLINFMAPNES-SDWTDASKSELYKSLFV-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06631-1", "uniprot_id": "BFR2_YEAST", "id": "Q06631-1", "name": "Protein BFR2", "aln": "-------MEKSLADQISDIAIKPVNKDFDIEDE----ENASLFQHNEKNGESDLSDYGNSNTEETKKAHYLEVEK---SKLRAEKGLELNDPKYTGVKGSRQALYEEVSENEDEEE---------------EEEEEEEKEEDALSFRTDSEDEEVEIDEEE------------------SDADGGET---------EEAQQKRHALSKLIQQETKQAINKLSQSVQRDASKGYSILQQTKLFDNIIDLRIKLQKAVIAANKLPLTTESWEEAKMDDSEETKRLLKENEKLFNNLFNRLINFRIKFQLGDHITQNEEVAKHKLSKKR--------------------------SLKELYQETNSLDSELKEYRTAVLNKWSTKVSSASGNAALSSNKFKAINLPADVQVENQLSDMSRLMKRTKLNRRNITPLYFQKDCANGRLPELISPVVKDSVDDNENSDDGLDIPKNYDPRRKDNNAIDITENPYVFDDEDFYRVLLNDLIDKKISNAHNSESAAITITSTNARSN-NKLKKNIDTKASKGRKLNYSVQDPIANYEAPITSGYKWSDDQIDEFFAGLLGQRVNFNENEDEEQHARIENDEELEAVKNDDIQIFG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:* ::..: * : : : . :.: : : : . .: : .. .* :.* . :. . * : :: . .: : . . . ... . . .* : . * ::. : :: : . . : .** :: :* :::.::: **: ** :*:** . : ... * *:: .: . *:. *:.:: : : : . ::. . . :: **. .* ** :.. : . :: :: : : . *:.::: : *. . ::**.***: *.:**: * *. .: : :. .*::*::* :*******.: * . : .: ** .* *:: .*: ", "identical_positions": 54, "similar_positions": 152, "identity": "8.75%" }, { "cls_id": "homologset.agr.RGD:620686", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48675-1", "uniprot_id": "DESM_RAT", "id": "P48675-1", "name": "Desmin", "aln": "MSQAYSSSQRVSSYRRTFGGAPGFSLGSPLSSPVFPRAGFGTKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGTTRAP-SYGAGELLDFSLADAVNQEFLATRTNEKVELQELNDRFANYFEKVRFLEQQNAALAAEVNRLKGREPTRVAELYEEEMRELRRQVEVLTNQRARVDVERDNLIDDLQRLKAKLQEEIQLREEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTFSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31001-1", "uniprot_id": "DESM_MOUSE", "id": "P31001-1", "name": "Desmin", "aln": "MSQAYSSSQRVSSYRRTFGGAPGFSLGSPLSSPVFPRAGFGTKGSSSSMTSRVYQVSRTSGGAGGLGSLRSSRLGTTRAP-SYGAGELLDFSLADAVNQEFLATRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPTRVAELYEEEMRELRRQVEVLTNQRARVDVERDNLIDDLQRLKAKLQEEIQLREEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEANGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTFSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17661-1", "uniprot_id": "DESM_HUMAN", "id": "P17661-1", "name": "Desmin", "aln": "MSQAYSSSQRVSSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGTTRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTYSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************.****************:******:*********************:*******:* *********************:*******************:***********************************:************************:****************:***************************************************************************************************************************************************************.*************************************************************:***********************************************", "identical_positions": 457, "similar_positions": 12, "identity": "97.23%" }, { "cls_id": "homologset.agr.RGD:620687", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09811-1", "uniprot_id": "PYGL_RAT", "id": "P09811-1", "name": "Glycogen phosphorylase, liver form", "aln": "-------------------------MAKPLTDQEKRRQISIRGIVGVEN--------------VAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQN-------------ACDEAIYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKARPEFMLPVHFYGRVEHTQAG------TKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKASKFGSKDGVGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWEITKKTFAYTNHTVLPEALERWPVDLVEKLLPRHLQIIYEINQKHLDRIVALFPKDIDRMRRMSLIEEEGGKR-INMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELE-PDKFQNKTNGITPRRWLLLCNPGLADLIAEKIG---EDYVKDLSQLTKLHSFVGDDIFLREIAKVKQENKLKFSQFLEKEYK-VKIN-----PSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIK---------KDPKKFFVPRTVIIGGKAAPGYHMAKMIIKLVTSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVAALDKKGYEAKEYYEALP-ELKLVIDQIDNGFFSPNQPDLFKDIINMLFYH-DRFKVFADYEAYVKCQEKVSQLYMNQK-AWNTMVLRNIAASGKFSSDRTIREYAKDIWNMEPSDLKISLSKESSNGVNANGK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ET01-1", "uniprot_id": "PYGL_MOUSE", "id": "Q9ET01-1", "name": "Glycogen phosphorylase, liver form", "aln": "-------------------------MAKPLTDQEKRRQISIRGIVGVEN--------------VAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQN-------------ACDEAIYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKARPEFMLPVHFYGRVEHTQTG------TKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKASKFGSKDGMGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWAKAWEITKKTFAYTNHTVLPEALERWPVELVEKLLPRHLEIIYEINQKHLDRIVALFPKDISRMRRMSLIEEEGGKR-INMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELE-PDKFQNKTNGITPRRWLLLCNPGLADLIAEKIG---EDYVKDLSQLTKLHSFVSDDIFLREIAKVKQENKLKFSQFLEKEYK-VKIN-----PSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIK---------KDPKKFFVPRTVIIGGKAAPGYHMAKMIIKLITSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVAALDKKGYEAKEYYEALP-ELKLVIDQIDNGFFSPNQPDLFKDIINMLFYH-DRFKVFADYEAYVKCQEKVSQLYMNQK-AWNTMVLKNIAASGKFSSDRTIKEYAKDIWNMEPSDLKISLSNESSNGVSANGK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P06737-1", "uniprot_id": "PYGL_HUMAN", "id": "P06737-1", "name": "Glycogen phosphorylase, liver form", "aln": "-------------------------MAKPLTDQEKRRQISIRGIVGVEN--------------VAELKKSFNRHLHFTLVKDRNVATTRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQN-------------ACDEAIYQLGLDIEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYGNPWEKSRPEFMLPVHFYGKVEHTNTG------TKWIDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKASKFGSTRGAGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWELTQKTFAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVALFPKDVDRLRRMSLIEEEGSKR-INMAHLCIVGSHAVNGVAKIHSDIVKTKVFKDFSELE-PDKFQNKTNGITPRRWLLLCNPGLAELIAEKIG---EDYVKDLSQLTKLHSFLGDDVFLRELAKVKQENKLKFSQFLETEYK-VKIN-----PSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIK---------KDPKKLFVPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRIDDVAALDKKGYEAKEYYEALP-ELKLVIDQIDNGFFSPKQPDLFKDIINMLFYH-DRFKVFADYEAYVKCQDKVSQLYMNPK-AWNTMVLKNIAASGKFSSDRTIKEYAQNIWNVEPSDLKISLSNES-NKVNGN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H0W7-1", "uniprot_id": "A0AC58H0W7_DANRE", "id": "A0AC58H0W7-1", "name": "Alpha-1,4 glucan phosphorylase", "aln": "---------------MFITIYGLIRMATPLTDQEKRKQISIRGIVGVEN--------------VAELKKGFNRHLHFTLVKDRNVATPRDYYFALSHTVRDHLVGRWIRTQQFCYEADPKRVYYLSLEFYMGRTLQNTMINLGLQN-------------ACDEAIYQLGLDMEDLEEMEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIKDGWQVEEADDWLRYGNPWEKARPEFMLPVHFYGRVEEEEGKE-----PKWVDTQVVLAMPYDTPIPGYMNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKTSKRNTSGPLS--FDSFPDKVAIQLNDTHPAMAIPELMRIFVDIEKLDWDTAWDITKRTFAYTNHTVLPEALERWPVDLMEKLLPRHLQIIYKINLIHLNHIASLFPEDMDRIRRMSLIEEGGGKR-VNMAHLCIVGSHKVNGVAKIHSDIIKRDVFQDFSELE-PEKFQNKTNGITPRRWLLLCNPGLADLIAEAIG---EEYVKDLTQLQKLNDLVDDEAFIRDVAKVKQDNKLKFAHYLEKIYK-VDIN-----PASMFDVHVKRIHEYKRQLLNCLHVITMYNRIK---------SHPTKPFIPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPVIGRKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVNDVAELDKKGYNALQYYENLS-ELKRAINQIKSGYFSPKQPEMFSDIINMLFHH-DRFKVFADYESYVKCQDRVSALYKDQR-EWTRVVIKNIAASGKFSSDRTITEYATEIWGVEPTDLKIPPPGEPREALEETARSLRKT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XTL9-1", "uniprot_id": "PYG_DROME", "id": "Q9XTL9-1", "name": "Glycogen phosphorylase", "aln": "-------------------------MSKPQSDADRRKQISVRGIAEVGN--------------VTEVKKNFNRHLHYTLVKDRNVSTLRDYYFALANTVKDNMVGRWIRTQQHYYEKDPKRVYYLSLEYYMGRSLTNTMINLGIQS-------------ECEEAMYQLGLDIENLEEMEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFAQKIKNGEQVEEPDDWLRYGNPWEKARPEFMLPVNFYGRVIDTPEG------KKWVDTQRVFAMPYDNPIPGYNNNHVNTLRLWSAKSPIDFNLKFFNDGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFMCAATLQDIIRRYKASKFGSREAVRNTFDHFPDKVAIQLNDTHPSLAIPELMRILVDEEHLTWEKAWDITVRSCAYTNHTVLPEALERWPVSLLESILPRHLQIIYHINFLHMENVKKKFPDDLDRMRRMSMVEEDGEKR-INMAHLSIVGSHAVNGVAAIHSQILKDSLFHDFYEME-PQKFQNKTNGITPRRWLLLCNPGLSDLIAEKIG---DEWPVHLDQLVALKKWAKDPNFQRNVARVKQENKLKLAAILEKDYG-VKIN-----PSSMFDIQVKRIHEYKRQLLNCLHIITLYNRIK---------KDPTANFTPRTIMIGGKAAPGYYVAKQIIKLICAVGNVVNNDPIVGDKLKVIFLENYRVTLAEKIMPAADLSEQISTAGTEASGTGNMKFQLNGALTIGTLDGANVEMAEEMGLDNIFIFGMTVDEVEALKKKGYNAYDYYNANP-EVKQVIDQIQGGFFSPGNPNEFKNIADILLKY-DHYYLLADYDAYIKAQDLVSKTYQNQA-KWLEMSINNIASSGKFSSDRTIAEYAREIWGVEPTWEKLPAPEDQPQN-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06738-1", "uniprot_id": "PHSG_YEAST", "id": "P06738-1", "name": "Glycogen phosphorylase", "aln": "MPPASTSTTNDMITEEPTSPHQIPRLTRRLTGFLPQEIKSIDTMIPLKSRALWNKHQVKKFNKAEDFQDRFIDHVETTLARSLYNCDDMAAYEAASMSIRDNLVIDWNKTQQKFTTRDPKRVYYLSLEFLMGRALDNALINMKIEDPEDPAASKGKPREMIKGALDDLGFKLEDVLDQEPDAGLGNGGLGRLAACFVDSMATEGIPAWGYGLRYEYGIFAQKIIDGYQVETPDYWLNSGNPWEIERNEVQIPVTFYGYVDRPEGGKTTLSASQWIGGERVLAVAYDFPVPGFKTSNVNNLRLWQARPTTEFDFAKFNNGDYKNSVAQQQRAESITAVLYPNDNFAQGKELRLKQQYFWCAASLHDILRRFKKSKRP--------WTEFPDQVAIQLNDTHPTLAIVELQRVLVDLEKLDWHEAWDIVTKTFAYTNHTVMQEALEKWPVGLFGHLLPRHLEIIYDINWFFLQDVAKKFPKDVDLLSRISIIEENSPERQIRMAFLAIVGSHKVNGVAELHSELIKTTIFKDFVKFYGPSKFVNVTNGITPRRWLKQANPSLAKLISETLNDPTEEYLLDMAKLTQLGKYVEDKEFLKKWNQVKLNNKIRLVDLIKKENDGVDIINREYLDDTLFDMQVKRIHEYKRQQLNVFGIIYRYLAMKNMLKNGASIEEVAKKYPRKVSIFGGKSAPGYYMAKLIIKLINCVADIVNNDESIEHLLKVVFVADYNVSKAEIIIPASDLSEHISTAGTEASGTSNMKFVMNGGLIIGTVDGANVEITREIGEDNVFLFGNLSENVEELR---YNHQYHPQDLPSSLDSVLSYIESGQFSPENPNEFKPLVDSIKYHGDYYLVSDDFESYLATHELVDQEFHNQRSEWLKKSVLSVANVGFFSSDRCIEEYSDTIWNVEPVT-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. :. *: : : . . :.:. * *:. **.:. . * * : :::*::* * :*** **********: ***:* *::**: ::. . *: :**:.:*:: : * ****************:***** *:.*:***:******* *** :* *** .* **. ***** * *. :** *** * :*:. : *:*:.** *:**: .. **.:***.*:.. :*:: ** *** ::* ::: **.*: ******** :********:** **:*:*::**:* ** : ***:**********::** ** *::** *:* * **::. :: *******: ****:*** *. :*****:***.** .:: : **.*:. : *:*::** . :* :.**.*.***.* ***** :**:::* :*:** :: *.** * ********** .**.*:.**:* :. ::: .: :* * . * * :. :** :**::: ::. *.* ::**::********** ** : :* * :* .. : :. ::***:****::** ****: .*.::**** : ***:*: :*.*: ** ::**:****:***********.**** :**.* ***:******::.* * :*:*:** ::* * *: : : . .:. .:. *..* *** :*: *. : : : : * : : *:::*: :: *. : : * : .:* * ***** * **: **.:** ", "identical_positions": 359, "similar_positions": 239, "identity": "38.35%" }, { "cls_id": "homologset.agr.RGD:620688", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKB0-1", "uniprot_id": "HCN1_RAT", "id": "Q9JKB0-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGGGKPNSASNSR---------------DDGNSVYPSKAPAT--GPAAADKRLGTPPGGGAAG-KEHGNSVCFKVD------GGGG--------EEPAGSFEDAEGP-----------------------------------------------------------------------------------------------------------------------------------RRQYG------------------------------------------------------------------------------------------FMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNEDSSE-IILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMDS-------EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILSELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKS-SKEMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQKDLNTGVFNNQENEILKQIVKHDREMVQAIPPINYPQMTALNCTSSTTTPTSRMRTQSPPVYTATSLSHSNLHSPSPSTQTPQPSAILSPCSYTTAVCSPPIQSPLATRTFHYASPTASQLSLMQQPQPQLQQSQVQQTQPQPQPQPQQPQQQQQQQQQQQQQQQQQQQQQQ--------PQTPGSSTPKNEVHKSTQALHNTNLTREVRPLSASQPSLPHEVSTMISRPHPTVGESLASIPQPMATVHSTGLQAGSRSTVPQRVTLFRQMSSGAIPPNRGVPPAPPPPAAVQ-RESPSVLNKDPDAEKPRFASNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88704-1", "uniprot_id": "HCN1_MOUSE", "id": "O88704-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGGGKPNSASNSR---------------DDGNSVFPSKAPAT--GPVAADKRLGTPPGGGAAG-KEHGNSVCFKVD------GGGG--------EEPAGSFEDAEGP-----------------------------------------------------------------------------------------------------------------------------------RRQYG------------------------------------------------------------------------------------------FMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNEDSSE-IILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMDS-------EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILSELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKS-SKEMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQKDLNTGVFNNQENEILKQIVKHDREMVQAIPPINYPQMTALNCTSSTTTPTSRMRTQSPPVYTATSLSHSNLHSPSPSTQTPQPSAILSPCSYTTAVCSPPIQSPLATRTFHYASPTASQLSLMQQPQQQLPQSQVQQTQTQTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQTPGSSTPKNEVHKSTQALHNTNLTKEVRPLSASQPSLPHEVSTLISRPHPTVGESLASIPQPVAAVHSTGLQAGSRSTVPQRVTLFRQMSSGAIPPNRGVPPAPPPPAAVQ-RESPSVLNTDPDAEKPRFASNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60741-1", "uniprot_id": "HCN1_HUMAN", "id": "O60741-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGGGKPNSSSNSR---------------DDGNSVFPAKASATGAGPAAAEKRLGTPPGGGGAGAKEHGNSVCFKVD------GGGGGGGGGGGGEEPAGGFEDAEGP-----------------------------------------------------------------------------------------------------------------------------------RRQYG------------------------------------------------------------------------------------------FMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNEDSSE-IILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMDS-------EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKS-SKEMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQKDLNTGVFNNQENEILKQIVKHDREMVQAIAPINYPQMTTLNSTSSTTTPTSRMRTQSPPVYTATSLSHSNLHSPSPSTQTPQPSAILSPCSYTTAVCSPPVQSPLAARTFHYASPTASQLSLMQQQ----PQQQVQQSQP-PQTQPQQPSPQ---------------------------PQTPGSSTPKNEVHKSTQALHNTNLTREVRPLSASQPSLPHEVSTLISRPHPTVGESLASIPQPVTAVPGTGLQAGGRSTVPQRVTLFRQMSSGAIPPNRGVPPAPPPPAAALPRESSSVLNTDPDAEKPRFASNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z9N7-1", "uniprot_id": "A1Z9N7_DROME", "id": "A1Z9N7-1", "name": "", "aln": "MHVKHTQRRVSGPGAFGTFTNDQRASRDNLCPDNQQQQQQRHSHSHQHLVRQSLVSLSNGQPAASAAPDSVSLLRAGDDQQQHPQQPHLQQQQQQQQHLQQQQQRHRSSSSRLSTSGISKQNSSDSRSGLRILDSSHSPVSCGTQSVSSTGGQSALYDACHEYSRSLSAAAAEGAASLLKSHYSDQQLAQTEPDPEPDPERDRDRDRDRDRDRERERRHLTNLNLNLSSEYDYSGSDKQQLVNETYIFKCIANSPSFLRTNKIKEQSKKLRNLSLKTRTAKKKGQIISKSNAVSDNSLHPGDKYLNLYLVEKKHSLQPQVASTSSSINTTHPQASSAPASSSSTCTKAPQLPALSAVAARQQQLLLNGSLKGKGQSQSQGQSRQTLPGHRASVRSESGSGSSHTIPATGKSPPVPHSLAAKISSSASGSKNCNLLSASSNSCHKLNAHAQGSGAGSGSGSGSGSGPPGHSHYAAASPKSSVSSNGHLNKYCLTDLTRRKAEFNRQLSAPTDYTHHSSSNGSQQEGSSEANEGHEPVGESTITVASAGVSYPHPYSYPYHYAHHASSATAPANLKASLQLHSFGSHHPCPYPARPTSTSCTNSFNRRHIRRHKGKLGDRLLSGDSEESVRCSYCSVLNVNDNDLRISFENTCTDSLVTAFDDEALLICDQGTEMVHFDDVSLYGTPKEEPMPNIPIVSEKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYILQNLQKKSADRRGRMNRKDKDGLTKSNLILKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDEQ------LSNPESNTITAVVN-------------------------------------------------------------------------------------------------------------------------------------------------------------------ALAAEADDCKDDDMDLKEN---------------LLHGSESSIAEPVQTIREGLP----------------------RPRSGEFRALFEGNTP---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* *:.:* .:** .... . *:.. :. * * .:..*. .. . ... *.*:: *.*. *. .. * .* **: * *:: *: * :** *::::::***:**: **: * **:*.*:*** *.******* **:::*.**:*:**.*:**.:: :* ** ** ***:**:*:::***** :::*.:* :*****:* :**::**.:*:*****:******.:: *. :: ::.*****:*::*:***:********:**: ****:: : ::**..:****** ****: **.********:**.**.:.***:**: :. * :***:*************** .* *::*:*:****** ******:*:**** ************:** ****:**:::*** ****:* :*:*******:**** **.**.: ***:::*:***.***::*:*****.***: :::**::******* **:**::*.******.**..:: . . .*:************:.**.*****:***.*:*****:** **::**:**:::**** :**::***: .*: ** :: :.* *.: :. :*: . :: :: :.. *::. * * .: *:.* *: *.*. * ** : .* * ", "identical_positions": 345, "similar_positions": 219, "identity": "21.95%" }, { "cls_id": "homologset.agr.RGD:620689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKA9-1", "uniprot_id": "HCN2_RAT", "id": "Q9JKA9-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDARGGGG------RPGDSPGATP-----APGPPPPPPPPAP------------------PQPQPPPAPPPNP--TTPSHP--------ESADEPGPRSRL------------CSRDSSC----TPGAA---KGGANGECGRGEPQCS---PEGPARGP------------------------------------KVSFSCRGAASGPA----AAEEAG--------------------------------------------------------------------------------------SEE----------------------------------------------------AGPAGEPRG------------SQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDN-TEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDS-------EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLSSGVFNNQENAIIQEIVKYDREMVQQAELG--QR-----------VGLFPPPPPP-QVTSAIATLQQAVAMSFCPQVARPLVGPLALGSPRLVR-------RAPPGPLPPAASPGPP-AASPPAAPSSPRAP----RTSPYG-VPGS---------PATRVGPALPARRLSRASRPLSASQPSLP---HGAPAPSPAASARPASSST-----------------PRLGPAPTTRTAAPSPDRRDSASPGAASGLDPLDSA-----------RSRLSSNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88703-1", "uniprot_id": "HCN2_MOUSE", "id": "O88703-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDARGGGG------RPGDSPGTTP-----APGPPPPPPPPAP------------------PQPQPPPAPPPNP--TTPSHP--------ESADEPGPRARL------------CSRDSAC----TPGAA---KGGANGECGRGEPQCS---PEGPARGP------------------------------------KVSFSCRGAASGPS----AAEEAG--------------------------------------------------------------------------------------SEE----------------------------------------------------AGPAGEPRG------------SQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDN-TEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDS-------EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLSSGVFNNQENAIIQEIVKYDREMVQQAELG--QR-----------VGLFPPPPPP-QVTSAIATLQQAVAMSFCPQVARPLVGPLALGSPRLVR-------RAPPGPLPPAASPGPP-AASPPAAPSSPRAP----RTSPYG-VPGS---------PATRVGPALPARRLSRASRPLSASQPSLP---HGVPAPSPAASARPASSST-----------------PRLGPAPTARTAAPSPDRRDSASPGAASGLDPLDSA-----------RSRLSSNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UL51-1", "uniprot_id": "HCN2_HUMAN", "id": "Q9UL51-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDARGGGG------RPGESPGATP-----APGPPPPPPPAPPQQ---------------QPPPPPPPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGRL------------RSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGP------------------------------------KVSFSCRGAASGPAPGPGPAEEAG--------------------------------------------------------------------------------------SEE----------------------------------------------------AGPAGEPRG------------SQASFMQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDN-TEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDS-------EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLNSGVFNNQENAIIQEIVKYDREMVQQAELG--QR-----------VGLFPPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVR-------RPPPGPAPAAASPGPPPPASPPGAPASPRAP----RTSPYGGLPAA---------PLA--GPALPARRLSRASRPLSASQPSLP---HGAPG--PAASTRPASSST-----------------PRLGPTPAARAAAPSPDRRDSASPGAAGGLDPQDSA-----------RSRLSSNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T6V3-1", "uniprot_id": "A0A8N7T6V3_DANRE", "id": "A0A8N7T6V3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEAEDGDEDHKETRRGDILDSSSKMKTVAPGGGAASSRISNNKDFASC----------GRSTESAALLGHGDASRSGAHS--------DGEDATGMRCVINGD---------CRRDDSVCSVLSKLEKQTGGGFPASACHSSTSSMDGSVTPAAAAAPP-----------------------------ADKKDSRVSFSSAAPAHGPS----PSNPAGNSVSFSK-------------------------------------------------------------------------------SEDGQ-------------------------------------------------ITAEDGEARD------------NQT-YMQRQFSAMLQPGVNKFSLRMFGSQKAVEKEQERVKSAGNWIIHPYSDFRFYWDFTMLMFMVGNLIIIPVGITFFKEETTTPWIIFNVVSDTFFLMDLVLNFRTGIVYEDN-TEIILDPEKIKKKYLKTWFVVDFVSSIPVDYIFLIVEKGIDS-------EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVMRIINLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSLNKMVNDSWSELYSFALFKAMSHMLCIGYGRQAPESMSDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEESILEELNEPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNIGMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILMHKVQHDLNSGVFNNRENEMIQEIVKYDREMVKLVKQGDMQRPRAMSMTPSTHGSMFGPSSQP-STSSAIATLQQAVAMSFCPQMGNPLMGSGSVQSPRMVRRFQVVQTQTPPGSQYSTLARASALASTPVHSPLATTARTFQYGSSPPGAPSGSQLSLVQQLVPSPTHRPAVHRSTLTQDARALSASQPSLRPDMIQPVAPSPPQSTRVSSTSIGPPQNLPGPTGLRGSIPPRMALTHQMSVGAFPPASLPQMRPSLDSGLPKKDSISSLPETEQHHIRSRLSSNL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9N7-1", "uniprot_id": "A1Z9N7_DROME", "id": "A1Z9N7-1", "name": "", "aln": "MHVKHTQRRVSGPGAFGTFTNDQRASRDNLCPDNQQQQQQRHSHSHQHLVRQSLVSLSNGQPAASAAPDSVSLLRAGDDQQQHPQQPHLQQQQQQQQHLQQQQQRHRSSSSRLSTSGISKQNSSDSRSGLRILDSSHSPVSCGTQSVSSTGGQSALYDACHEYSRSLSAAAAEGAASLLKSHYSDQQLAQTEPDPEPDPERDRDRDRDRDRDRERERRHLTNLNLNLSSEYDYSGSDKQQLVNETYIFKCIANSPSFLRTNKIKEQSKKLRNLSLKTRTAKKKGQIISKSNAVSDNSLHPGDKYLNLYLVEKKHSLQPQVASTSSSINTTHPQASSAPASSSSTCTKAPQLPALSAVAARQQQLLLNGSLKGKGQSQSQGQSRQTLPGHRASVRSESGSGSSHTIPATGKSPPVPHSLAAKISSSASGSKNCNLLSASSNSCHKLNAHAQGSGAGSGSGSGSGSGPPGHSHYAAASPKSSVSSNGHLNKYCLTDLTRRKAEFNRQLSAPTDYTHHSSSNGSQQEGSSEANEGHEPVGESTITVASAGVSYPHPYSYPYHYAHHASSATAPANLKASLQLHSFGSHHPCPYPARPTSTSCTNSFNRRHIRRHKGKLGDRLLSGDSEESVRCSYCSVLNVNDNDLRISFENTCTDSLVTAFDDEALLICDQGTEMVHFDDVSLYGTPKEEPMPNIPIVSEKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYILQNLQKKSADRRGRMNRKDKDGLTKSNLILKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGK-NPNIMHQKDEQLS-----NPESNTITAVVN-------------------------------ALAAEADDCKDDDMDLKENLLHGSESSIAEPVQTIREG-----------------------------------------------------------------------------LPRPRSGEFRALFEGNTP-------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... : .. ::. ** . .. . . . . . . : .: . . . . . . . .* .* : * * . *.: : .* **: .. * .: .: ::: *: : :** *::::::***:**: :*: * *::* *:*** *.******: **:::*.****:**.*:**::: :: ** ** :***:**:*:*:******: :** ::****: * *:**:***.:*::****:******.:: :. :: ::.*****:*::*:***:********:**: ****:: : ::**..*** *** ****: **.***********.** :.***:* : : * * **:**************** .*:*::*:******** ******:*:**** ************:** ****:**:::*** *:**:* :*:*******:***: ** **. ***:::*:***.****:*:*****.***: ::***::******* **:*****.******.***.:: *: .**************..**.*****:***.*:*****:** **::**:**:::**** :**::*** *. ::*: :.:*. * *. * :*: .. . . .. *:: . ..:..*: : . :... * ", "identical_positions": 331, "similar_positions": 214, "identity": "21.52%" }, { "cls_id": "homologset.agr.RGD:62069", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47915-1", "uniprot_id": "RL29_MOUSE", "id": "P47915-1", "name": "Large ribosomal subunit protein eL29", "aln": "MAKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLKKMQANNAKAVSARAEAIKALVKPQAIKPKMPKGP--KLKRLAFIAHPKLGKRIRSYMAKGQRLCQPKPKVQTKAG--AKAPAKAQASAPAQAPKGAQAPKGAQAPVKAP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "W4VSN7-1", "uniprot_id": "W4VSN7_MOUSE", "id": "W4VSN7-1", "name": "60S ribosomal protein L29", "aln": "MAKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLEKMQASNAKAVSVHAEAIKALVKPQAIKPKMPKGP--KLKRLAFIAHPKLGKRIRSYMAKGQRLCQPKPKVQTKAG--AKAPAKAQASTPAQAPKGAQAPKGAQAPVKAP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25886-1", "uniprot_id": "RL29_RAT", "id": "P25886-1", "name": "Large ribosomal subunit protein eL29", "aln": "MAKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLKKMQANNAKAVSARAEAIKALVKPQAVKPKMPKGSSRKLSRLAFIAHPKLGKKIRSYMAKGRRLCQPKPKVQTKAE--AKAPAKAQAKAPAQAPK------GAQAPVKAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47914-1", "uniprot_id": "RL29_HUMAN", "id": "P47914-1", "name": "Large ribosomal subunit protein eL29", "aln": "MAKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLKKMQANNAKAMSARAEAIKALVKPKEVKPKIPKGVSRKLDRLAYIAHPKLGKRARARIAKGLRLCRPKAKAKAKAKDQTKAQAAAPASVPAQAPK------RTQAPTKASE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05747-1", "uniprot_id": "RL29_YEAST", "id": "P05747-1", "name": "Large ribosomal subunit protein eL29", "aln": "MAKSKNHTAHNQTRKAHRNGIKKPKTYKYPSLKGVDPKFRRN----HKHALHG-------TAKALAAAKK-----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q24154-1", "uniprot_id": "RL29_DROME", "id": "Q24154-1", "name": "Large ribosomal subunit protein eL29", "aln": "MAKSKNHTNHNQNKKAHRNGIKRPLRKRHESTLGMDVKFLINQRYARKGNLSREESVKRYNERIASQKGK-------PKPVTL----------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******** ***.:* ******:* :: * *:* ** * :* . : : : ", "identical_positions": 26, "similar_positions": 11, "identity": "15.76%" }, { "cls_id": "homologset.agr.RGD:620690", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6S1-1", "uniprot_id": "Q6P6S1_RAT", "id": "Q6P6S1-1", "name": "RING-type E3 ubiquitin transferase", "aln": "---------------------MENSTVLSNWTKENKEKMKYDFSCELYRMSTYSAFPRGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDSPTEKHRQFYPSCSFVQTLLSGGLQSAAKNTSPAKSRFAHSLP--LEQG----GIHSSLPSNPLNSRAVEDFS-LRMNPCSYAMSTEEARFLSYSMWPLSFLSPAELAKAGFYYTGPGDRVACFACGGKLSNWEPNDDPLSEHRRHFPHCPFLEN----------TSETQRFSVSNLSMQTH----SARMRTFLYWPSSVLVQPEQLASAGFYYVDHNDDVKCFCCDGGLRCWEPGDDPWIEHAKWFPRCEFLIRMKGQEFVDEIQARYPHLLEQLLSTSDTSEEENADP--PVVHLGPGENW-EDAVMMNTPVVKAALDMGFSRSLVRQTVQRQILATGENYRTVSDIVSALLNAEDERREEEKERQSEETASGDLSLIRKNRMALFQQLTCVIPILDDLLEASVLTKEEHDIIRQKTQIPLQARELIDTILVKGNAAASVFKNSLKEVDSTLYEHLFVEKTMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDREVSIVFIPCGHLVVCRECAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62210-1", "uniprot_id": "BIRC2_MOUSE", "id": "Q62210-1", "name": "Baculoviral IAP repeat-containing protein 2", "aln": "MDKTVSQRLGQGTLHQKLKRIMEKSTILSNWTKESEEKMKFDFSCELYRMSTYSAFPRGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDSPVEKHRQFYPSCSFVQTLLSASLQSPSKNMSPVKSRFAHSSP--LERG----GIHSNLCSSPLNSRAVEDFS-SRMDPCSYAMSTEEARFLTYSMWPLSFLSPAELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPHCPFLEN----------TSETQRFSISNLSMQTH----SARLRTFLYWPPSVPVQPEQLASAGFYYVDRNDDVKCFCCDGGLRCWEPGDDPWIEHAKWFPRCEFLIRMKGQEFVDEIQARYPHLLEQLLSTSDTPGEENADPTETVVHFGPGESS-EDVVMMSTPVVKAALEMGFSRSLVRQTVQRQILATGENYRTVNDIVSVLLNAEDERREEEKERQTEEMASGDLSLIRKNRMALFQQLTHVLPILDNLLEASVITKQEHDIIRQKTQIPLQARELIDTVLVKGNAAANIFKNSLKEIDSTLYENLFVEKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDREVSIVFIPCGHLVVCQECAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13490-1", "uniprot_id": "BIRC2_HUMAN", "id": "Q13490-1", "name": "Baculoviral IAP repeat-containing protein 2", "aln": "MHKTASQRLFPGPSYQNIKSIMEDSTILSDWTNSNKQKMKYDFSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSASLGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLEN----------SLETLRFSISNLSMQTH----AARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTSDTTGEENADP--PIIHFGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTTGENYKTVNDIVSALLNAEDEKREEEKEKQAEEMASDDLSLIRKNRMALFQQLTCVLPILDNLLKANVINKQEHDIIKQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTLYKNLFVDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24307-1", "uniprot_id": "DIAP2_DROME", "id": "Q24307-1", "name": "Death-associated inhibitor of apoptosis 2", "aln": "-------------------------------------MTELGMELESVRLATFGEWPLNAPVSAEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAERHRRSSPICSMVLAPNHCGNVPRSQESDNEGNSVVDSPE----------------------------------SCSCPDLLLEANRLVTFKDWPNPNITPQALAKAGFYYLNRLDHVKCVWCNGVIAKWEKNDNAFEEHKRFFPQCPRVQMGPLIEFATGKNLDELGIQPTTLPLRPKYACVDARLRTFTDWPISNIQPASALAQAGLYYQKIGDQVRCFHCNIGLRSWQKEDEPWFEHAKWSPKCQFVLLAKGPAYVSEVLATTAANASSQPATAPAP-------------------TLQADVLMDEAPAKEALALGIDGGVVRNAIQRKLLSSGCAFSTLDELLHDIFDDAGAGAALEVREPPEPSAP--------------------------------FIEPCQATTSKAASVPIPVADSIPAKPQAAEAVANISK--------------ITDEIQKMSVATPNGNLSLEEENRQLKDARLCKVCLDEEVGVVFLPCGHLATCNQCAPSVANCPMCRADIKGFVRTFLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24306-1", "uniprot_id": "DIAP1_DROME", "id": "Q24306-1", "name": "Death-associated inhibitor of apoptosis 1", "aln": "--MASVVADLPSYGPIAFDQVDNNTNATQLFKNNINKTRMNDLNREETRLKTFTDWPLDW-LDKRQLAQTGMYFTHAGDKVKCFFCGVEIGCWEQEDQPVPEHQRWSPNCPLLRRRTTNNVPINAEALDRILPPIS-------------------------------------YDICGANDSTLEMREHAYAEGVIP--MSQLIQSIGMNAVNAAGSVTGTAAPQPRVTVATHASTATQATGDVQPETCRPS---------------AASGNYFPQYPEYAIETARLRTFEAWPRNLKQKPHQLAEAGFFYTGVGDRVRCFSCGGGLMDWNDNDEPWEQHALWLSQCRFVKLMKGQLYIDTVAAKP--------------------------------------VLAEEKEESSSIGG-----------------------------VAVASTQASEEEQQTSLSSEEAVSG----------------------------------------DVAPSVAPTAATRIFNKIVEATAVA--------------------------TPSTNSSGSTS------IPEEKLCKICYGAEYNTAFLPCGHVVACAKCASSVTKCPLCRKPFTDVMRVYFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. * *: *: :* . :. ..*. *:: * :.:*. * : :. *: *. .*:: * *.:: . :: . . . * :: . . : *: . . * . . : .. : . . . . :. .. **:*** ** . . **.**::* .* *:** *. ** *: *:** :** * .:*.*: ** ::. : . *: . . :: : . : .* .. ..:. . * . *.* : .. : : : : **:* . * . .*:****:..* :**.*: :**:** :.. :*.::*", "identical_positions": 71, "similar_positions": 123, "identity": "11.2%" }, { "cls_id": "homologset.agr.RGD:620691", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKA8-1", "uniprot_id": "HCN3_RAT", "id": "Q9JKA8-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEEARPAVGDGEAATP-ARETPPAAPAQARAASG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVPESAPEP-------------KRRQLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAE-ILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLD-----AEVYKTARALRIVRFTKILSLLRLLRLSRLIRYMHQWEEIFHMT------------------------------YDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSMNRMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLS-VLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLRRIGKKNSILQRKRSEPSPGSSSGGVMEQHLVQHDRDMARGIRGLAPGTGARLSGKPVLWEPLVHAPLQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSARRSAGSPASPLVPVRAGPLLARGPWASTSRLPAPPARTLHASLSRTGRSQVSLLGPPPGGGGRRLGPRGRPLSASQPSLPQRATGDGSPRRKGSGSERLPPSGLLAKPPGTVQPSRSSVPEPVTPRGPQISANM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88705-1", "uniprot_id": "HCN3_MOUSE", "id": "O88705-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEEARPAAGAGEAATP-ARETPPAAPAQARAASG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVPESAPEP-------------KRRQLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAE-ILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLD-----AEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSMNRMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLS-VLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLRRIGKKNSILQRKRSEPSPGSS-GGVMEQHLVQHDRDMARGVRGLAPGTGARLSGKPVLWEPLVHAPLQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSARRSAGSPASPLVPVRAGPLLARGPWASTSRLPAPPARTLHASLSRTGRSQVSLLGPPPGGGARRLGPRGRPLSASQPSLPQRATGDGSPRRKGSGSERLPPSGLLAKPPGTVQPPRSSVPEPVTPRGPQISANM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P1Z3-1", "uniprot_id": "HCN3_HUMAN", "id": "Q9P1Z3-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAEQRPAAGASEGATPGLEAVPPVAPPPATAASG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIPKSGPEP-------------KRRHLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAE-ILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLD-----AEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLS-VLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLLRIGKKNSILQRKRSEPSPGSS-GGIMEQHLVQHDRDMARGVRGRAPSTGAQLSGKPVLWEPLVHAPLQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSAWRSAGSPASPLVPVRAG------PWASTSRLPAPPARTLHASLSRAGRSQVSLLGPPPGGGGRRLGPRGRPLSASQPSLPQRATGDGSPGRKGSGSERLPPSGLLAKPPRTAQPPRPPVPEPATPRGLQLSANM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z9N7-1", "uniprot_id": "A1Z9N7_DROME", "id": "A1Z9N7-1", "name": "", "aln": "MHVKHTQRRVSGPGAFGTFTNDQRASRDNLCPDNQQQQQQRHSHSHQHLVRQSLVSLSNGQPAASAAPDSVSLLRAGDDQQQHPQQPHLQQQQQQQQHLQQQQQRHRSSSSRLSTSGISKQNSSDSRSGLRILDSSHSPVSCGTQSVSSTGGQSALYDACHEYSRSLSAAAAEGAASLLKSHYSDQQLAQTEPDPEPDPERDRDRDRDRDRDRERERRHLTNLNLNLSSEYDYSGSDKQQLVNETYIFKCIANSPSFLRTNKIKEQSKKLRNLSLKTRTAKKKGQIISKSNAVSDNSLHPGDKYLNLYLVEKKHSLQPQVASTSSSINTTHPQASSAPASSSSTCTKAPQLPALSAVAARQQQLLLNGSLKGKGQSQSQGQSRQTLPGHRASVRSESGSGSSHTIPATGKSPPVPHSLAAKISSSASGSKNCNLLSASSNSCHKLNAHAQGSGAGSGSGSGSGSGPPGHSHYAAASPKSSVSSNGHLNKYCLTDLTRRKAEFNRQLSAPTDYTHHSSSNGSQQEGSSEANEGHEPVGESTITVASAGVSYPHPYSYPYHYAHHASSATAPANLKASLQLHSFGSHHPCPYPARPTSTSCTNSFNRRHIRRHKGKLGDRLLSGDSEESVRCSYCSVLNVNDNDLRISFENTCTDSLVTAFDDEALLICDQGTEMVHFDDVSLYGTPKEEPMPNIPIVSEKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYILQNLQKKSADRRGRMNRKDKDGLTKSNLILKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDEQLSNPES-------------NTITAVVNALAAEADDCKDDDMDLKENLLHG---------------------------------------SESSIAEPVQTIREG-------------LPRP----------RSGEFRALFEGNTP----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * ...: * . ..*.. : .:*. *:. * * : :* : :*** *::::::***:**: *: * *::* *:*** *.******* ****:*.***:***.*:**::: *. **.** ****:**:*:*:******: ::.** ::* *: * .:******::*******:*****:.: :*: :: ::.*****:*::*:***:********:**: ****:: : ::**..:****** ****: **.***********.**.:.***:*.: : * .*** ***************: .* .:.*:******** ******:*:**** ************:** ****:**:::*** * **** **:*******:**** ******* ***::**:.**.*** :*:**:**..**: *:***::*******::::**::* ******.*::. *:*.* * *:************..**.*****:***.*:********.**:::*:**:::**** :** :***: .*:::* .: * .* . :: :.. *. :. ... * * *:*. * .* *.*: .:* * ** * *:*. :. : * .* ", "identical_positions": 343, "similar_positions": 187, "identity": "23.21%" }, { "cls_id": "homologset.agr.RGD:620692", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0I6-1", "uniprot_id": "XIAP_RAT", "id": "Q9R0I6-1", "name": "E3 ubiquitin-protein ligase XIAP", "aln": "------------------MTFNSFEGSRTVVPADTNKDEEFVEEFNRLKTFANFPSSSPVSASTLARAGFLYTGEGDTVQCFSCHAAVDRWQYGDSAVGRHRRISPNCRFINGFYFENGATQSTSPGIQNGQYKSENCVGNRNHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMCSEEARLKTFQNWPDYAHLSPRELASAGLYYTGIDDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNVNVRSES-GVSSDRNFPNSTNSPRNPAMAEYDARIVTFGTWLYS--VNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLDEKGQEYINNIHLTHSLGESVVRTAEKTP---------------SVTKKIDDTIFQNPMVQEAIRMGFNFKDIKKTMEEKLQTSGS-------------------------NYLSLEVLIADLVSAQKDNSQDES------------SQTSLQKDISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCCTVITFKQKIFMS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60989-1", "uniprot_id": "XIAP_MOUSE", "id": "Q60989-1", "name": "E3 ubiquitin-protein ligase XIAP", "aln": "------------------MTFNSFEGTRTFVLADTNKDEEFVEEFNRLKTFANFPSSSPVSASTLARAGFLYTGEGDTVQCFSCHAAIDRWQYGDSAVGRHRRISPNCRFINGFYFENGAAQSTNPGIQNGQYKSENCVGNRNPFAPDRPPETHADYLLRTGQVVDISDTIYPRNPAMCSEEARLKSFQNWPDYAHLTPRELASAGLYYTGADDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNVNVRSES-GVSSDRNFPNSTNSPRNPAMAEYEARIVTFGTWTSS--VNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLDEKGQEYINNIHLTHSLEESLGRTAEKTP---------------SLTKKIDDTIFQNPMVQEAIRMGFSFKDIKKTMEEKIQTSGS-------------------------SYLSLEVLIADLVSAQKDNTEDES------------SQTSLQKDISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P98170-1", "uniprot_id": "XIAP_HUMAN", "id": "P98170-1", "name": "E3 ubiquitin-protein ligase XIAP", "aln": "------------------MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP---------------SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGS-------------------------NYKSLEVLVADLVNAQKDSMQDES------------SQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96P09-1", "uniprot_id": "BIRC8_HUMAN", "id": "Q96P09-1", "name": "Baculoviral IAP repeat-containing protein 8", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGYEARLITFGTWMYS--VNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYLLEEKGHEYINNIHLTRSLEGALVQTTKKTP---------------SLTKRISDTIFPNPMLQEAIRMGFDFKDVKKIMEERIQTSGS-------------------------NYKTLEVLVADLVSAQKDTTENEL------------NQTSLQREISPEEPLRRLQEEKLCKICMDRHIAVVFIPCGHLVTCKQCAEAVDRCPMCSAVIDFKQRVFMS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24307-1", "uniprot_id": "DIAP2_DROME", "id": "Q24307-1", "name": "Death-associated inhibitor of apoptosis 2", "aln": "-----------------------------------MTELGMELESVRLATFGEWPLNAPVSAEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAERHRRSSPICSMVLAPNHCGNVPRSQES-------------DNEGNSVVDSPES--------------------CSCPDLLLEANRLVTFKDWPN-PNITPQALAKAGFYYLNRLDHVKCVWCNGVIAKWEKNDNAFEEHKRFFPQCPRVQMG--PLIEFATGKNLDELGIQPTTLPLRPKYACVDARLRTFTDWPISNIQPASALAQAGLYYQKIGDQVRCFHCNIGLRSWQKEDEPWFEHAKWSPKCQFVLLAKGPAYVSEVLATTAANASSQPATAPAPTLQADVLMDEAPAKEALALGIDGGVVRNAIQRKLLSSGCAFSTLDELLHDIFDDAGAGAALEVREPPEPSAPFIEPCQATTSKAASVPIPVADSIPAKPQAAEAVANISKITDEIQKMSVATPNGNLSLEEENRQLKDARLCKVCLDEEVGVVFLPCGHLATCNQCAPSVANCPMCRADIKGFVRTFLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24306-1", "uniprot_id": "DIAP1_DROME", "id": "Q24306-1", "name": "Death-associated inhibitor of apoptosis 1", "aln": "MASVVADLPSYGPIAFDQVDNNTNATQLFKNNINKTRMNDLNREETRLKTFTDWPLD-WLDKRQLAQTGMYFTHAGDKVKCFFCGVEIGCWEQEDQPVPEHQRWSPNCPLLRRRTTNN--------------------------------------------------------VPINAEALDRILPPISYDICGANDSTLEMREHAYAEGVIPMSQLIQSIGMNAVNAAGSVTGTAAPQPRVTVATHASTATQATGDVQPETCRPSAASGNYFPQYPEYAIETARLRTFEAWPRNLKQKPHQLAEAGFFYTGVGDRVRCFSCGGGLMDWNDNDEPWEQHALWLSQCRFVKLMKGQLYIDTVAAKPVLAEEKEESSSIGG------------------------VAVASTQASEEEQQTSLSSEEAVSGDVAPSVAP---------------------------TAATRIFNKIVEATAVATPSTN-----------------------SSGSTSIPEEKLCKICYGAEYNTAFLPCGHVVACAKCASSVTKCPLCRKPFTDVMRVYFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **: ** * . **.**:: *:*:** *. ** .*: .::** :** * . *::: ** *:. : . :: : . . :. . : .. : . . : * .. : : :***:* . . .*:****:.:* :** :* .**:* : : ::*", "identical_positions": 44, "similar_positions": 59, "identity": "7.73%" }, { "cls_id": "homologset.agr.RGD:620693", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2N5-1", "uniprot_id": "NXPH3_RAT", "id": "Q9Z2N5-1", "name": "Neurexophilin-3", "aln": "MQLTRCCFVFLVQGSLYLVICGQEDGPPGSEDPEHDDHEGQPRPRVPRKRGHISPKSRPLANSTLLGLLAPPGEVWGILGQPPNRPKQSPLPSTKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKIVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91VX5-1", "uniprot_id": "NXPH3_MOUSE", "id": "Q91VX5-1", "name": "Neurexophilin-3", "aln": "MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPEHDDHEGQPRPRVPRKRGHISPKSRPLANSTLLGLLAPPGEVWGVLGQPPNRPKQSPLPSTKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFRHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95157-1", "uniprot_id": "NXPH3_HUMAN", "id": "O95157-1", "name": "Neurexophilin-3", "aln": "MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPERDDHEGQPRPRVPRKRGHISPKSRPMANSTLLGLLAPPGEAWGILGQPPNRPNHSPPPSAKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFQHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********************:**********:************************:**************.**:********::** **:****************************************:**********************************************************************************:**********************************", "identical_positions": 241, "similar_positions": 10, "identity": "95.63%" }, { "cls_id": "homologset.agr.RGD:620694", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99M63-1", "uniprot_id": "SMU1_RAT", "id": "Q99M63-1", "name": "WD40 repeat-containing protein SMU1", "aln": "MSIEIESSDVIRLIMQYLKENSLHRALATFTEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2TAY7-1", "uniprot_id": "SMU1_HUMAN", "id": "Q2TAY7-1", "name": "WD40 repeat-containing protein SMU1", "aln": "MSIEIESSDVIRLIMQYLKENSLHRALATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UKJ7-1", "uniprot_id": "SMU1_MOUSE", "id": "Q3UKJ7-1", "name": "WD40 repeat-containing protein SMU1", "aln": "MSIEIESSDVIRLIMQYLKENSLHRALATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZVA0-1", "uniprot_id": "SMU1_DANRE", "id": "Q7ZVA0-1", "name": "WD40 repeat-containing protein SMU1", "aln": "MSIEIESADVIRLIMQYLKENSLHRTLAMLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQSLKWQQHQGLLPPGMTIDLFRGKAAVKDVEEERFPTQLARHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMSFSRDTEMLATGAQDGKIKVWKIQSGQCLRRYERAHSKGVTCLSFSKDSTQILSASFDQTIRIHGLKSGKCLKEFRGHSSFVNEATLTPDGHHAISASSDGTVKVWNMKTTECTSTFKSLGTSAGTDITVNNVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCTLSPRGEWIYCVGEDYVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIGTYSEDGLLKLWKP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VE18-1", "uniprot_id": "Q9VE18_DROME", "id": "Q9VE18-1", "name": "WD40 repeat-containing protein SMU1", "aln": "MSIEIESADVIRLIQQYLKESNLMKTLQTLQEETGVSLNTVDSVDGFVQDISNGHWDTVLKVTQSLKLPDKKLLNLYEQIVLELIELRELGAARSLLRQTDPMTMLKQQEPERYIHLENMLQRAYFDPREAYAEGSSKEKRRTVIAQELSGEVHVVPSSRLLALLGQALKWQQHQGLLPPGTTIDLFRGKAAMKDQEEEMYPTQLFRQIKFGQKSHVECAQFSPDGQYLITGSVDGFLEVWNFTTGKVRKDLKYQAQDQFMMMEQAVLALNFSRDSEMVASGAQDGQIKVWRIITGQCLRKFEKAHTKGITCLQFSRDNSQVLSASFDYTVRLHGLKSGKMLKEFKGHSSFVNEATFTPDGHSVLSASSDGTVKVWSLKTTECVATYKPLG----NELAVNTVLILPKNPEHFIVCNRSNTVVIMNMQGQIVRSFSSGKREGGAFISATLSPRGEFIYCAGEDQVLYCFSVSSGKLERTLNVHEKDVIGLTHHPHQNLLASYSEDGLLKLWKP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:****** *****..* ::* : *** ********::.** **..*******:. ********.*::****:*********************** **** :*********:* *:********.:********:.*** *:*** ***.***:*****:************* **********:** *** :**** *:************:********:*******:*********:**********:****::***.: ****:**:*:*****:****:* :*****::*:**:**:***.**:*.:*:****** *:*:******* ****:**********:* *** :*********:*.:***** *:*.** .:::**.*::********:***************************** *:..:******:***.*** ******. :*******.********::*******:.:************", "identical_positions": 392, "similar_positions": 88, "identity": "76.41%" }, { "cls_id": "homologset.agr.RGD:620695", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97946-1", "uniprot_id": "VEGFD_MOUSE", "id": "P97946-1", "name": "Vascular endothelial growth factor D", "aln": "MYGEWGMGNILMMFHVYLVQGFRSEHGPVKDFSFERSSRSMLERSEQQIRAASSLEELLQIAHSEDWKLWRCRLKLKSLASMDSRSASHRSTRFAATFYDTETLKVIDEEWQRTQCSPRETCVEVASELGKTTNTFFKPPCVNVFRCGGCCNEEGVMCMNTSTSYISKQLFEISVPLTSVPELVPVKIANHTGCKCLPTGPRHPYSIIRRSIQTPEEDECPHSKKLCPIDMLWDNTKCKCVLQDETPLPGTEDHSYLQEPTLCGPHMTFDEDRCECVCKAPCPGDLIQHPENCSCFECKESLESCCQKHKIFHPDTCSCEDRCPFHTRTCASRKPACGKHWRFPKETR-AQGLYSQENP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35251-1", "uniprot_id": "VEGFD_RAT", "id": "O35251-1", "name": "Vascular endothelial growth factor D", "aln": "MYGEWAAVNILMMSYVYLVQGFSIEHRAVKDVSLERSSRSVLERSEQQIRAASTLEELLQVAHSEDWKLWRCRLKLKSLANVDSRSTSHRSTRFAATFYDTETLKVIDEEWQRTQCSPRETCVEVASELGKTTNTFFKPPCVNVFRCGGCCNEESVMCMNTSTSYISKQLFEISVPLTSVPELVPVKIANHTGCKCLPTGPRHPYSIIRRSIQIPEEDQCPHSKKLCPVDMLWDNTKCKCVLQDENPLPGTEDHSYLQEPALCGPHMMFDEDRCECVCKAPCPGDLIQHPENCSCFECKESLESCCQKHKMFHPDTCR---------SMVFSLSP------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43915-1", "uniprot_id": "VEGFD_HUMAN", "id": "O43915-1", "name": "Vascular endothelial growth factor D", "aln": "MYREWVVVNVFMMLYVQLVQGSSNEHGPVK-----RSSQSTLERSEQQIRAASSLEELLRITHSEDWKLWRCRLRLKSFTSMDSRSASHRSTRFAATFYDIETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCSHSKKLCPIDMLWDSNKCKCVLQEENPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNCSCFECKESLETCCQKHKLFHPDTCSCEDRCPFHTRPCASGKTACAKHCRFPKEKRAAQGPHSRKNP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** *::** :* **** ** .** ***:* ************:*****:::************:***::.:****:************* ******************************:**********************.::******************************:***********.************* ****.*.*******:*****..*******:*.**.******:****:****** ***********:*** ******:************:******:****** * .. ", "identical_positions": 263, "similar_positions": 37, "identity": "73.26%" }, { "cls_id": "homologset.agr.RGD:620696", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIX5-1", "uniprot_id": "CHD8_RAT", "id": "Q9JIX5-1", "name": "ATP-dependent chromatin remodeler CHD8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADPIMDLFDDPNLFGLDSLTDDSFNQVTQDPIEEALGLPSSLDSLDQMNQDGGSGDVGNSSASDLVPPPEETASTELPKE-STAPAPESLTLHDYTTQPTSQEQPAQPVLQTS--TPTSGLLQVSKSQEILSQGNP------------------------FMGVSATAVSPSNTG------------GQPSQS------------APKIVILKAPPNSSVTGAHVAQIQAQGITSTAQPLVAGTANGGKVTFTKVLTGTPLRPGVSIVSGNTVLATKVPGN-----QAAVQRIVQPSR-PVKQLVLQPVKG--SAPAGNPGATGPPLKPAVTLTSTP-------------------AQGESKRITLVLQQPQSGGPQG--------------------HRHVVLGSLPGKIVLQ------GNQLAALTQAKSAQ-GQPAKVVT---IQLQVQQPQQKIQIVPQPPSSQPQPQ--PPPSAQPLTLSSVQQAQIMGPGQNPGQRLSVPLKMVLQPQAGSSQGASSGLSVVKVLS---------------------------------------------------ASEVAALSSPASCAPHTAGKTG--MEENRRLEHQKKQEKAN--RIVAEAIA------------------------------------------------------------------------------------------------------------RARARGEQNIP----------------RVLNEDELPS---------------------------------------------------------------------------------VRPEEEGEKKRRKKS----------------------------------------------------------------------------------SGERLKEEKPKKSKT------AAASKTKGKSKLN----TITPVVGKKRK-------------------------------------------------------------------------------------------------------------RNTSSD---------------------------------NSDVEVMPAQSPREDEESSIQKRRSNRQVKRKKYTEDLDIKITDDEE---------------------------------------------EEEVDVTGPIKPE-------PILPEPVPEPDGETLPSMQ-----FFVENPSEEDAAIVDKVLSMRVVKKELPSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYTEAEEFFVKYKNYSYLHCEWATISQLEK-DKRIHQKLKRFKTKMAQMRHFFH-EDEEPFNPDYVEVDRILDESHSVDKDNGEPVIYYLVKWCSLPYEDSTWELKEDVDEGKIREFKRIQ--SRHPELKRVNRPQANAWKKLELSHEYKNRNQLREYQLEGVNWLLFNWYNRQNCILADEMGLGKTIQSIAFLQEVYNVGIHGPFLVIAPLSTITNWEREFNTWTEMNTIVYHGSLASRQMIQQYEMYCKDSRGRLIPGAYKFDALITTFEMILSDCPELREIEWRCVIIDEAHRLKNRNCKLLDSLKHMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSQFPSESEFLKDFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLSKGAG-HTNMPNLLNTMMELRKCCNHPYLINGAEEKILMEFREACHIIPQDFHLQAMVRSAGKLVLIDKLLPKLKAGGHKVLIFSQMVRCLDILEDYLIQRRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRDGNITGIQQFSKKEIEDLLRKGAYAAIMEEDDEGSKFCEEDIDQILLRRTTTITIESEGKGSTFAKASFVASENRTDISLDDPNFWQKWAKKADLDMDLLNS--KNNLVIDTPRVRKQTRHFSTLKDDDLVEFSDLESEDDERPR-------SRRHDRHHT-------------------------------YGRTDCFRVEKHLLVYGWGRWRDILSHGRFKRRMTERDVETICRAILVYCLLHYRGDENIKSFIWDLISPAENGK-TKELQNHSGLSIPVPRGRKGKKVKSQST------------------FDIHKADWIRKYNPDT------------------------------LFQDESYKKHLKHQCNKVLLRVRMLYYLRQEVIGDQAEKVLGGAIASEIDIWFPVVDQLEVPTTWWDSEADKSLLIGVFKHGYEKYNTMRADPALCFLEKAGR-----------------------------------------------------------------------------------------------------PDDKAIAAEHRVLDNFSDLVEGID------------------------------------------FDKDCE---------------------------------------------------------------DPEYKPLQGPPKDPDDEGDPLMMMDEEISVIDGDEAPVTQQPG-----HLFWPPGSALTARLRRLVTAYQRSYKREQMKIEAAERGD-----------------------------------------------------------------------------------------------------------------------------------RRRRRCEAAFKLKEIARREKQ-QRWTRREQTDFYRVVSTFGVE---------YDPDNMQFHWDRFRTFARLDKKTDESLTKYFHGFVAMCRQVCRLPPAAGDEPPDPNLFIEPITEERASRTLYRIELLRRLREQVLCHPLLEDRLALCQPPGLELPKWWEPVRHDGELLRGAARHGVSQTDCNIMQDPDFSFLAA----------------RMNYMQNHQAGASAASLSRCSTPLLHQQCTSRTASPSPLRPDVPAEKSPEENAVQVPSLDSLTLKLEDEVVARSRLTPQDYEIRVASSDT---------------------------------------------------------------------APLS-RSVPPVKLEDDDDSDSELDLSKLSPSSSSSSSSSSSSSSSDESEDEK------------EEKLTADRSRPKLYDEESLLSLTMSQDGFPNEDGEQMTPELLLLQERQRA-------------------------------------------------------------------SEWPKDRVLINRIDLVCQAVLSGKWPSNRRSQEMTTGG-----------------------------------------ILGPGNHLLDSPSLTPGEYGDSPVPTPRSSS-------------AASMVEEEASAVTTAAAQFTKLRRGM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DEKEFTVQIKDEEG---------------------------------------LKLTFQKHRLMANGVMGDGHPLFHK------------------------------------------------------------------------------------------------KKGNRKKLVELEVECMEEPNHLDVDLETRIPVINKVDGTLLVGDEAPRRAELDMWLQGHPEFAVDPRFLAYMEERRKQKWQRCKKNNK----TELNCLGMEPVQPANSRNGKKGHYAETAFNRVLPGPIAPENSKKRVRRTRPDLSKMMALMQGGSTGSLSLHNTFQHS---------------------------SSNLQSVSSLG----------------------------------------------------------HSSATSAS---------------------------------------------------------------------------------------LPFMPFVMGGAAAPPHVDSSTMLHHHHHHPHPHHHHHHHPGLRTTGYPSSPATTTSGTALRLPTLQHEDDDEEEDEDDDDLSQG-YDSSERDFSLIDDPMMP---------------------------------------------ANSDSSDDADD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q09XV5-1", "uniprot_id": "CHD8_MOUSE", "id": "Q09XV5-1", "name": "ATP-dependent chromatin remodeler CHD8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADPIMDLFDDPNLFGLDSLTDDSFNQVTQDPIEEALGLPSSLDSLDQMNQDGGGGDVGNSSASDLVPPPEETASTELPKE-STAPAPESLTLHDYTTQPTSQEQPAQPVLQTS--TPTAGLLQVSKSQEILSQGNP------------------------FMGVSATGVSPSNTG------------GQPSQS------------APKIVILKAPPNSSVTGTHVAQIQAQGITSTAQPLVAGTANGGKVTFTKVLTGTPLRPGVSIVSGNTVLATKVPGN-----QAAVQRIVQPSR-PVKQLVLQPVKG--SAPAGNPGAAGPPLKPAVTLTSTP-------------------TQGESKRITLVLQQPQSGGPQG--------------------HRHVVLGSLPGKIVLQ------GNQLAALTQAKNAQ-GQPAKVVT---IQLQVQQPQQKIQIVPQPPSSQPQPQPQPPPSAQPLTLSSVQQAQIMGPGQNPGQRLSVPLKMVLQPQAGSSQGASSGLSVVKVLS---------------------------------------------------ASEVAALSSPASCAPHTAGKTG--MEENRRLEHQKKQEKAN--RIVAEAIA------------------------------------------------------------------------------------------------------------RARARGEQNIP----------------RVLNEDELPS---------------------------------------------------------------------------------VRPEEEGEKKRRKKS----------------------------------------------------------------------------------SGERLKEEKPKKSKT------AAASKTKGKSKLN----TITPVVGKKRK-------------------------------------------------------------------------------------------------------------RNTSSD---------------------------------NSDVEVMPAQSPREDEESSIQKRRSNRQVKRKKYTEDLDIKITDDEE---------------------------------------------EEEVDVTGPIKPE-------PILPEPVQEPDGETLPSMQ-----FFVENPSEEDAAIVDKVLSMRVVKKELPSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYTEAEEFFVKYKNYSYLHCEWATISQLEK-DKRIHQKLKRFKTKMAQMRHFFH-EDEEPFNPDYVEVDRILDESHSVDKDNGEPVIYYLVKWCSLPYEDSTWELKEDVDEGKIREFKRIQ--SRHPELRRVNRPQANAWKKLELSHEYKNRNQLREYQLEGVNWLLFNWYNRQNCILADEMGLGKTIQSIAFLQEVYNVGIHGPFLVIAPLSTITNWEREFNTWTEMNTIVYHGSLASRQMIQQYEMYCKDSRGRLIPGAYKFDALITTFEMILSDCPELREIEWRCVIIDEAHRLKNRNCKLLDSLKHMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSQFPSESEFLKDFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLSKGAG-HTNMPNLLNTMMELRKCCNHPYLINGAEEKILMEFREACHIIPQDFHLQAMVRSAGKLVLIDKLLPKLKAGGHKVLIFSQMVRCLDILEDYLIQRRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRDGNITGIQQFSKKEIEDLLRKGAYAAIMEEDDEGSKFCEEDIDQILLRRTTTITIESEGKGSTFAKASFVASENRTDISLDDPNFWQKWAKKADLDMDLLNS--KNNLVIDTPRVRKQTRHFSTLKDDDLVEFSDLESEDDERPR-------SRRHDRHHT-------------------------------YGRTDCFRVEKHLLVYGWGRWRDILSHGRFKRRMTERDVETICRAILVYCLLHYRGDENIKSFIWDLISPAENGK-TKELQNHSGLSIPVPRGRKGKKVKSQST------------------FDIHKADWIRKYNPDT------------------------------LFQDESYKKHLKHQCNKVLLRVRMLYYLRQEVIGDQAEKVLGGAIASEIDIWFPVVDQLEVPTTWWDSEADKSLLIGVFKHGYEKYNTMRADPALCFLEKAGR-----------------------------------------------------------------------------------------------------PDDKAIAAEHRVLDNFSDLVEGID------------------------------------------FDKDCE---------------------------------------------------------------DPEYKPLQGPPKDPDDEGDPLMMMDEEISVIDGEEAQVTQQPG-----HLFWPPGSALTARLRRLVTAYQRSYKREQMKMEAAERGD-----------------------------------------------------------------------------------------------------------------------------------RRRRRCEAAFKLKEIARREKQ-QRWTRREQTDFYRVVSTFGVE---------YDPDNMQFHWDRFRTFARLDKKTDESLTKYFHGFVAMCRQVCRLPPAAGDEPPDPNLFIEPITEERASRTLYRIELLRRLREQVLCHPLLEDRLALCQPPGLELPKWWEPVRHDGELLRGAARHGVSQTDCNIMQDPDFSFLAA----------------RMNYMQNHQAGASAASLSRCSTPLLHQQCTSRTASPSPLRPDAPVEKSPEESTVQVPNLESLTLKLEDEVVARSRLTSQDYEVRVGSSDT---------------------------------------------------------------------APLS-RSVPPVKLEDEDDSDSELDLSKLSPSSSSSSSSSSSSSSTDESEDEK------------EEKLTADRSRPKLYDEESLLSLTMSQDGFPNEDGEQMTPELLLLQERQRA-------------------------------------------------------------------SEWPKDRVLINRIDLVCQAVLSGKWPSNRRSQEVTAGG-----------------------------------------ILGPGNHLLDSPSLTPGEDGDSPVPTPRSGS-------------AASMAEEEASAVTTAAAQFTKLRRGM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DEKEFTVQIKDEEG---------------------------------------LKLTFQKHRLMANGVMGDGHPLFHK------------------------------------------------------------------------------------------------KKGNRKKLVELEVECMEEPNHLDLDLETRIPVINKVDGTLLVGDEAPRRAELEMWLQGHPEFAVDPRFLAYMEERRKQKWQRCKKNNK----AELNCLGMEPVQPANSRNGKKGHYAETAFNRVLPGPVAPENSKKRVRRTRPDLSKMMALMQGGSTGSLSLHNTFQHS---------------------------SSNLQSVSSLG----------------------------------------------------------HSSTTSAS---------------------------------------------------------------------------------------LPFMPFVMG-AAAPPHVDSSTMLHHHHHHPHPHHHHHHHPGLRTTGYPSSPATTTSGTALRLPTLQPEDDDEEEDEEDDDLSQG-YDSSERDFSLIDDPMMP---------------------------------------------ANSDSSEDADD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCK8-1", "uniprot_id": "CHD8_HUMAN", "id": "Q9HCK8-1", "name": "ATP-dependent chromatin remodeler CHD8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADPIMDLFDDPNLFGLDSLTDDSFNQVTQDPIEEALGLPSSLDSLDQMNQDGGGGDVGNSSASELVPPPEETAPTELSKE-STAPAPESITLHDYTTQPASQEQPAQPVLQTS--TPTSGLLQVSKSQEILSQGNP------------------------FMGVSATAVSSSSAG------------GQPPQS------------APKIVILKAPPSSSVTGAHVAQIQAQGITSTAQPLVAGTANGGKVTFTKVLTGTPLRPGVSIVSGNTVLAAKVPGN-----QAAVQRIVQPSR-PVKQLVLQPVKG--SAPAGNPGATGPPLKPAVTLTSTP-------------------TQGESKRITLVLQQPQSGGPQG--------------------HRHVVLGSLPGKIVLQ------GNQLAALTQAKNAQ-GQPAKVVT---IQLQVQQPQQKIQIVPQPPSSQPQPQ--QPPSTQPVTLSSVQQAQIMGPGQSPGQRLSVPVKVVLQPQAGSSQGASSGLSVVKVLS---------------------------------------------------ASEVAALSSPASSAPHSGGKTG--MEENRRLEHQKKQEKAN--RIVAEAIA------------------------------------------------------------------------------------------------------------RARARGEQNIP----------------RVLNEDELPS---------------------------------------------------------------------------------VRPEEEGEKKRRKKS----------------------------------------------------------------------------------AGERLKEEKPKKSKT------SGASKTKGKSKLN----TITPVVGKKRK-------------------------------------------------------------------------------------------------------------RNTSSD---------------------------------NSDVEVMPAQSPREDEESSIQKRRSNRQVKRKKYTEDLDIKITDDEE---------------------------------------------EEEVDVTGPIKPE-------PILPEPVQEPDGETLPSMQ-----FFVENPSEEDAAIVDKVLSMRIVKKELPSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYTEAEEFFVKYKNYSYLHCEWATISQLEK-DKRIHQKLKRFKTKMAQMRHFFH-EDEEPFNPDYVEVDRILDESHSIDKDNGEPVIYYLVKWCSLPYEDSTWELKEDVDEGKIREFKRIQ--SRHPELKRVNRPQASAWKKLELSHEYKNRNQLREYQLEGVNWLLFNWYNRQNCILADEMGLGKTIQSIAFLQEVYNVGIHGPFLVIAPLSTITNWEREFNTWTEMNTIVYHGSLASRQMIQQYEMYCKDSRGRLIPGAYKFDALITTFEMILSDCPELREIEWRCVIIDEAHRLKNRNCKLLDSLKHMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSQFPSESEFLKDFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLSKGAG-HTNMPNLLNTMMELRKCCNHPYLINGAEEKILTEFREACHIIPHDFHLQAMVRSAGKLVLIDKLLPKLKAGGHKVLIFSQMVRCLDILEDYLIQRRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRDGNITGIQQFSKKEIEDLLRKGAYAAIMEEDDEGSKFCEEDIDQILLRRTTTITIESEGKGSTFAKASFVASENRTDISLDDPNFWQKWAKKADLDMDLLNS--KNNLVIDTPRVRKQTRHFSTLKDDDLVEFSDLESEDDERPR-------SRRHDRHHA-------------------------------YGRTDCFRVEKHLLVYGWGRWRDILSHGRFKRRMTERDVETICRAILVYCLLHYRGDENIKGFIWDLISPAENGK-TKELQNHSGLSIPVPRGRKGKKVKSQST------------------FDIHKADWIRKYNPDT------------------------------LFQDESYKKHLKHQCNKVLLRVRMLYYLRQEVIGDQAEKVLGGAIASEIDIWFPVVDQLEVPTTWWDSEADKSLLIGVFKHGYEKYNTMRADPALCFLEKAGR-----------------------------------------------------------------------------------------------------PDDKAIAAEHRVLDNFSDIVEGVD------------------------------------------FDKDCE---------------------------------------------------------------DPEYKPLQGPPKDQDDEGDPLMMMDEEISVIDGDEAQVTQQPG-----HLFWPPGSALTARLRRLVTAYQRSYKREQMKIEAAERGD-----------------------------------------------------------------------------------------------------------------------------------RRRRRCEAAFKLKEIARREKQ-QRWTRREQTDFYRVVSTFGVE---------YDPDTMQFHWDRFRTFARLDKKTDESLTKYFHGFVAMCRQVCRLPPAAGDEPPDPNLFIEPITEERASRTLYRIELLRRLREQVLCHPLLEDRLALCQPPGPELPKWWEPVRHDGELLRGAARHGVSQTDCNIMQDPDFSFLAA----------------RMNYMQNHQAGAPAPSLSRCSTPLLHQQYTSRTASPLPLRPDAPVEKSPEETATQVPSLESLTLKLEHEVVARSRPTPQDYEMRVSPSDT---------------------------------------------------------------------TPLVSRSVPPVKLEDEDDSDSELDLSKLSPSSSSSSSSSSSSSSTDESEDEK------------EEKLTD-QSRSKLYDEESLLSLTMSQDGFPNEDGEQMTPELLLLQERQRA-------------------------------------------------------------------SEWPKDRVLINRIDLVCQAVLSGKWPSSRRSQEMVTGG-----------------------------------------ILGPGNHLLDSPSLTPGEYGDSPVPTPRSSS-------------AASMAEEEASAVSTAAAQFTKLRRGM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DEKEFTVQIKDEEG---------------------------------------LKLTFQKHKLMANGVMGDGHPLFHK------------------------------------------------------------------------------------------------KKGNRKKLVELEVECMEEPNHLDVDLETRIPVINKVDGTLLVGEDAPRRAELEMWLQGHPEFAVDPRFLAYMEDRRKQKWQRCKKNNK----AELNCLGMEPVQTANSRNGKKGHHTETVFNRVLPGPIAPESSKKRARRMRPDLSKMMALMQGGSTGSLSLHNTFQHS---------------------------SSGLQSVSSLG----------------------------------------------------------HSSATSAS---------------------------------------------------------------------------------------LPFMPFVMGGAPSSPHVDSSTMLHHHHHHPHPHHHHHHHPGLRAPGYPSSPVTTASGTTLRLPPLQPEEDDDEDEEDDDDLSQG-YDSSERDFSLIDDPMMP---------------------------------------------ANSDSSEDADD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R0I6-1", "uniprot_id": "CHD8_DANRE", "id": "B0R0I6-1", "name": "ATP-dependent chromatin remodeler CHD8", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADPIMDLFDDTPLFNLDSLPEDAFSQGSSDPVEEALKL-----ALGQVDP-----------PTDPIPDPGVPILSDVVTDPALIPTPVSVPLQNLQTQQLSQIPHEVSVASAP--ISIQPSLSVASNS---SGAAT------------------------VLLSSSLGVPVSGAQ------------VTPQQQ------------TQQITAVTQQAAGQHAPKIVILKGPQGQTQVLQGVTGATGSPGKVTLARVLTGTPLRPGMAVVSGGTVLNATSPAQGQVKVGTGVQRLVQTANGPMKQVLLTSVPQTQSQVQTQPVQVQIPVQTQLQSPSQPQQLQ---------------AQIQAQTQVALQTQAQTQTPTSPAAAGIRPQSVTLSAVPQ--QVRFVLGSLPGKLVLQ------GDQLAALAQAKAGQTGAQAKVLT---IQLQVQQQPNQQGAKFQLVSGAANAG------------GSPQVVQIS-QGQG-GQRLAVPLKLLLQPQSNTVSSAGGAVSVVKVIN---------------------------------------------------TSAAGSTSGTTTTAASSGVRLAKIQEPVRRVETLCKQEKAN--RIVAEAIA------------------------------------------------------------------------------------------------------------RAKARGERNIP----------------RVLNQDELPAGQTSADLEGAGGA----------------------------------------------------------TGAKKKGGGGVGGGGGGSKKKSPSA----------------------------------------------------------------------------------GGAKMVVGGDKKSKAKTPVIPGGGSKSKSKTKLN----TIT-LVGKKRK-------------------------------------------------------------------------------------------------------------RNPSSD---------------------------------HSDVDLSPPVSPRTLEEEMSQKRRSNRQVKRKKYTEDLDIKITDDED---------------------------------------------ELDADVDVTTTPMPAVGHVQPLGAELPPELDGDGLPSMQ-----FFVENPSEEDAAIVDKILSMRVTKKEAR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYTNVEEFFVKYKNYSYMHCEWASLEQLER-DKRIHQKLKRFKTKQAQMRNLFQ-EDEEPFNPDYVEVDRILDESHSVDKDNGEPVVYYLVKWCSLPYEDATWELKEDVDEGKVEEFRKIE--SRQPRLKRTPRPAASAWKKLDESTEYKNGNQLREYQLEGVNWLLFNWYNRQNCILADEMGLGKTIQSIALLSEMFSAGVQSPFMIIAPLSTITNWEREFSNWTDMNAIVYHGSLASRQMIQQYEMYCKDDKGHLIPGAYKFDALITTFEMILSDCPELREISWRCVVIDEAHRLKNRNCKLLDSLKMLEIEHKVLLTGTPLQNTVEELFSLLHFLEPAQFPSEIEFLREFGDLKTEEQVQKLQSILKPMMLRRLKEDVEKNLAPKQETIIEVELTDVQKKYYRAILERNFSFLSMGATQNSNVPNLLNTMMELRKCCNHPYLITGAEEKIVSELREVYDPLAPDFHLQALVRSAGKLVLLDKLLPRLKAGGHKVLIFSQMVRCLDILEDYLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCVIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMLDKASLKLGLDRAVLQSMSGNKE--SSIQQFSKKEIEDLLRKGAYAAIMDENDEGSRFCEEDIDQILQRRATTITIESEGKGSTFSKASFVASENRTDIALDDPEFWQKWAKKADIDMDSLNR--KNTLVIDTPRVRKQTRQFSSLRGE-GGDLSDLDSDDDYPPHNSRQSRASRRSDRHSGGG-----------------------------YGRTDCFRVEKHLLVYGWGRWRDILSHARCKRRLSERDVETICRVILVFCLIHYRGDENIKSFIWELITPPENGREPQALLNHSGLSIPVPRGRKGKRVKAQSS------------------FDVQKVEWIRKYNPDS------------------------------LLLDDSYRKHLKHQCNKVLLRVRMLYYLKQEVIGEHADSVLSGADARDIDIWLPEMEQQDVPSGWWDAEADRCLLIGVYKHGYEMYTTMRADPCLCFVERCGR-----------------------------------------------------------------------------------------------------PNEQDINAEQQAAD--PELGEGGD------------------------------------------YDKYSE---------------------------------------------------------------DPEFKPATRHAKEMYEEGD-SVNADGEICVEDRSAPMQVEGPSSGSSDLCYWPTSSSLTARLRRLITAYQRSYRREQLKIEAAEKGD-----------------------------------------------------------------------------------------------------------------------------------RRRRRCEQATKLKEIARQERQ-QRWTRREECDFYRVVSTFGVERIKKETDA-PEGDEHHMDWNRFRSFARLDKKTDESLTRYFKCFMSMCRKVCHIRPGRGDESQDMSQSLAPITEERASRTLYRVTLLCRLRERVLPHPSLEERLSLAPQTS-DLPSWWSIPKHDHELLLAAARHGVSRTELSIFSDPLYSFSQS----------------RLDYLQNQQAQAAAQ-----------IHAFSQSQDPAGIKEEGLEDESRLLGVEALCPSDSPAMLLSHS---DSKVGIQAGWVWKKSKNN---------------------------------------------------------------------GPSE------RKLGGGGGGASDSD----SDSDSGSSSSSRHSGSSDDSGDSD------------VEREQAALKMCDGDEENSILSLTPSQEGAP--------PESLTDPLR----------------------------------------------------------------------VDWPKDRILINRIENLCSLVITGHWPSGRRYISDIQLN-----------------------------------------TVSDEHELGD-------DLGYSRVARKINST-------------LSAEALEGQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESEFTVKLLKEEG---------------------------------------LKLTFSKQALMPN---GEGS--------------------------------------------------------------------------------------------------------ARKKRKDHELEDAEG------------------------VLHAPRRRDLPNWLKENPDYEVEGDMLELLVNRTKRKRRRKRVEKG----AALT--GSERVKVIDIRTGKK-------FAGVFG--PALQDLREHLEEN-PDHAVAPEWSETVRHSGFLPEILFHRL---------------------------LSPHASIPKKS----------------------------------------------------------RHYLHTPS---------------------------------------------------------------------------------------LQTDDPLLGGGEGEMLVSDGAYMMDDEDLEDGGHLTSSHH-FLTPAYDVK-----------------MEPSALDMDGGDSLSQGGYDSSDREAILDDVIMAP---------------------------------------------KHSDTSSSSED-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z002-1", "uniprot_id": "B7Z002_DROME", "id": "B7Z002-1", "name": "", "aln": "MDGNAQNMFHGNHQGDPYYRYDAAAAAAAAAAANPRAMGPPGGYPPRHRPPHPLQQQPQYPSYQPTAENLYGLGAADHQAAMGLGVGVGVGAGMGDLSGWGAAPSVPGQAAAYPGAGLGAYGHPQAAPPSQQQRQSNASAYRQHMPAYGQQDQQKLASYGAQQSMMAGYGSLAPQQQQQQQPPTPQQQQQAQQVQQQAQQQQQQQQQQSQQQARLPQHYPQAPGQHPLYPGVGAPTVQAGQPPTPQAYAHSPYGSPMQHQPSRGAPQHVGYGHTGLDQASAYGQHVPGGAPPGHHLSAQQQQAAQQLGAHQQQQLQSQQQQQAQQQQPHVSLMQQQQLPGAGLPPPHMGMPPSYGSHHQQQQQQQQTQQQQQQSAPPYMSSSKHQQAAAQLNSSPQYRAPFPQLSPQMSPRPPTMSPHPQMSPRPVGVSPAKPPPPQQQQQQTQAQQPQQVVSNQPSQHSIQGMVGLPSPRPQPPTSGAGGAGAKGPAPVAAPVNTLQALEQMVMPSQALGLPPMDYPSAYRSAVGPRMPASPQQQQQQHQQWGAAHGAQHLAALQQQQAQQQQQQVQQQQQAPPQQQQQAAMLQAQQQHHQQQLSMYGQPMGQQPQTAQQQVVPPVTSQPPVVAASQQQQQQQHQQQSLNDQLQHSINDIVGGGNSSGATGGAQNQHQQQPQLAAMSSPLHQQNLPNMHHLIQPTMETTQPTQQQQQTSQQQQQPQQPQATLTSPHHQQMQHQSPIHQQQQSPHHQQHLPSYNQSQQQFDPFANILGDNQPAASQQTMSPAHVSSPVPAQMQQQQHQTQQQPSQQVPQSQQQQVSQPQQQTQQQQPSTPSHHLSSILNETANSNDSSTLAVAANDSNNSSSNSSTNSIVNNQPTSVHDSNSQSSINSSSNNQQQLLMDNTNSHGGNSESAQNAGVDVGLFDNNSMSSNSAAVAAVASNAASAAAALLDSNSQSSNAEFEKNQSEGEGLGVVEGVIANETDLPQDENSVSKTQDITLSTELPTIQDDLQEKPTAEMEQTQLGQSLGDLSKSLLEEPKTVEESGEDKSQSAPGVAPPADPIIPVTQPPQQQMPPIGMPMHPIAPGYEAQAQGQGHMPPMMPPYGGAPGMYPPYPMLHQQEIAALQQQIQELYCMPPGHELQHQDKLMRMQERLNLLTQHEVNDQCAGGPQCLLFQNVPPMYGPPGNPLLNQQMVESPQVSSTTGRGRGKSANKPRKPRAKKGEKAQVGQQQDLMDISGNVAMGAANAVSSIPTTQLPVSEDCVTQGAGDTSVVGMLEYSEGMGDLSQDVHSANELDTSTDGSGKKKKPRKPRTPKDPNKPPRDRTPKAKKPKDPNDPNSTETPAAVKKRAGASKRRKQYGEDGAEQTGEGSEVEDNKPLVPKAGSADGEAETTSGGTGVDGESPDYDDIPVSKIPRGSNEDEKEAEAGDETVDSVPDSAGDPASTPSRRDRKRSTARSRRNANSEEGGSARKNRGSLSAKALKKRRNRGRIVPESDGEDDTLDRTPPPSPPPDSEMDSNKRRSSRNTQRKKYIDDVMLRFSDDENSLLVASPVKKDKKPSANASNSNAGSDVEKTEPQSGAEGDAAQEVGEEKSNLPLDESSQLEASSSTSAVAEKERQISTDAANAAMSSKPNYVYINTGDEDSMVVQLVLAMRMGKRELILDKPKEKAPEPKQDEEKSELDEATTDKPEGDEKFKTEGESKKDLTDSEETKLESSAMEVDSKEESEPDDSKKSDEDNKDKDKMEVDDEVGKSDKESKPEEQSETVKTEENSKAIEEDKSSTVLTADHAKEPETVLEKMEVDEKANDDQSAVSKAEGSDEKSTDDSNPEEATTEKNKESLEIEGEKERVKEGEESVKKENDEKTEADMENKPEPVFIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAAKIRRFQQKQSQQLNIFENIEDEPFNQDFTEVDRVLDMSVHTDETSGETTKHYLVKWKSLPYEDCTWELEEDVDNDKIEQYLRFNKIPQRSEWKSKKRPHPELWKKLEKTPVYKGGNSLRPYQLEGLNWLKFSWYNTHNCILADEMGLGKTIQSLTFVHSVYEYGIRGPFLVIAPLSTIPNWQREFEGWTDMNVVVYHGSVTSKQMIQDYEYYYKTESGKVLKEPIKFNVLITTFEMIVTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISELFSLLNFLEPSQFSSQEEFMSEFGSLRTEEEVNKLQALLKPMMLRRLKDDVEKSLAPKEETIIEVELTNIQKKYYRGILEQNFSFLKKGTT-SANIPNLMNTMMELRKCCIHPYLLNGAEEQIQYDFKSQHGEDPESYYKN-LILSAGKMVLIDKLLPKLKANGHRVLIFSQMVRCLDILEDYLVYRKYPFERIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTAADTVIIYDSDWNPQNDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQSMNTQGSKDGNNKQLSKKEIEDLLKKGAYGAVMDDDNAGDKFCEEDIDSILKRRTQVITMESE-KGSTFSKASFAASGNRSDITIDDPDFWTKWAKKVDIDPDACERDETEDLVLSEPRRRTQIKRYG---HEDVMELNSEESSNENSDEEGGIGLRSRRRKEKRDRAREKKGNDEYIPRERDALAALGLEEIQYGNWAKSECFKVEKGLLSFGWGRWSELLELGQFKRGWRDVDVEDCARIILLYCLQVYKGDEKIKTFIWDLITPTEDGEVQKISRDHSGLHNLVPRGRNGGKSNKESTGVSTPAPGSASGSNSGNTTPAHKSSALDGSDKDSGGINASAVAAAVTSIHDPNHWSKKEKYDADAYLEGAYKKHLGRHANKVLLRVRMLYYIQHEVIGDFVQQIKDNTPISELPIRPPPTPDQVPSSWWNPICCDKSLLVGTYKHGCEMYRQMRADPNLCFVTHVGAGAAGDDLAVTSLPINEDDANSKHDDGDEVDDDGTTTTKDSDSTKLTGGDNKDSLLDPERPSSSGKSSSENASGGNDKTESENDATTVSESSYKSEVLPGKGSDLDVSVAQQDALSATPELANTSDPKMNKNDAQVSASVSCDPADSSSPEAAGKAQGTGVQTGDAGELDIESEKKDNEKETKESTGDAPAVEAKKDSAAIARAEGDKTESCTNNATTNISTTTTTTTITNTTTTTNNPSSKAANSNNTTDHANSNSHLGLDEEESVAGSYPPTVAAVED----ATTMWPSMQDLNTRLRRVITAYQRNYKKEELKLQQKAKLQALVSSTPPLSVPTTPTLQSMQMQLQSGSGSGGSGIGSSAQHDASGRSLQALMQSQGASTSAAAAAAASSAGGSCSGSGQVGMGGAGVMPAMPTAADISLMLSILNTTDVNQLANLDINKLAMYLVSMNNKMERQGKMELAAKERESQRLQLIPKKWNRREEYEFLRVLTGYGVDLHVSTPMASSNGSSLSPDWTKFKQMAHLERKSDETLTDYYKVFVAMCKRQAGLKLSESERGLEG--IIEEIEKEHAKLILDRLEVLAKLREVAR-NPMLEERLKLCTKNA-DTPDWWEPGRHDKELITAVLKHGLYRSETFIFNDPNFSFGESEKRFIRELEAQIQRTIKLEAFNAEKAEKLAAAEKDAATEKAAATEKAAAEKAASVKNEVIDLDDELMTNESVIKKESPVTPIKEEIKSEESPEKHDTADNLEDKNSDAEESTKIKGKEDFNPETTEKEALDESTNLNKDKSSTETLVPEIEDSKPSEDKMEVEELPVAENGEKEGSPEKCSDAEDKKFSEEKPSSPAVPDGKVSEMEADEAAPNTEENCSGDSESPEKECEDKVVEKVEEEKGENSYEKAEEQKEETEKLEKSSIESEPSEKSETVLEPEVAVPKKSTGDQDILDLVAGPSDPDDDEVMKEKEKAVEEECKKQAAELKARFPDLEVIQPATVKQQKLEKPKLEMCMIRWFKDFALERRIAHIVACVESGNWPVDSKYSAFATCKGATDLSIALHESIPHLSSLERRSTTPDVITITTDQGVTKHLQTSHMQQVASSASAASTSSGVPQVTQSKPSSSNSLPGLDAKSINAAVAAAVAAAAAGGNATSLSSLLPGMSLSAATGSSAGGVSGLSVPSAGSGVGKKRKRHIAIDVETERAKLHALLNSSTMAPKDWESEIANMEALSGSSGRGRGGNSSASSGMQPPPAHQHASLSRQSSGQFSKPAVPAMKTPPPSMGAPMDLSSSLPKMNMTEMLKSASSSGAIDLSEVQDFSMPSKKSSVHAALSSAFPSMGNKSKLDDTLNKLMKKNNCTIEEPVIGKEKKRKKLDEIVLGLSAAKEQKTFPDPSLPSSKKPQIPPSVSVTPANLQSSSNQQSNQKPFTITVTTVPGKSKSGSSNSGSGTGGSSSASGGGAGGSGLSALQNMAMGGLSSKDSLNALLAQTMATDPQTFLKQQQKMMQFLPPAQRKAYENMLAEMEQAMKISSKFSTNSPHDVKVNKWLSDMTSPLGDQLSIDYVGGGGASGSGSGNSRRSNRQQGNSQQSSSAAQLQKQQQQQQQQQQQQQQHSMPGPQNLTGEEPVPVINKQTGKRLGGNKAPQLKRLMQWLTENPNYEVDPKWLEQMQNPMSTPSPRPASMESGYGSSAVKSHGGRPLSNLSSTSSSSHTQQQSSAAQSQAGGNSGSSKKNSRQQTAASAALDQAALQFGSLAGLNPSLLANLPGLGAFDPKNPLAAFDPKNPLLSMSFGGMPGMGNIPGLGNLNNMNLFASLAGMGGLGNLAGMDTQSLAALMAAAGPTLGGLTGASGGAGSGKSQAQSQSSATSSSSSASKKKQQQQQQQAQNEAAQLAAAISASTGGSGASGGKNAAASASQLAAGFPFLFPNPSLLYPPMGLGGLNPYSLGSSGLGSAYDQLAQQYNLLNGATSSASNTSSTQSKSHQSQSKSSQSRNTTASANSAASLMNAMASMGGGASTVTTPSTSASGSGRGRQSSSRNQSQTTPTAADMAQLSSLLMPGADPHLLESLSRMSNMDLAQATRLMSSLGMPPLSGTPSSSGGGNTSTSKRSSQAANEANVQAKEQQKWLESLARGALPTDLAALQAFSQGKMPSTSGSNTGTSTSSSKSSKAAATAAAAQLPQIPGMSSDFPQAFLAEMAAQAMAAAGGSLPLSGPGSLASLAGLTGGSAGGGGSSASGSTSHSSSKRQREQDAFKQQMDYYTKTLGLGSGISLIPTSSAGGSSASSSAANAAAAAYAAALDAEQQHQQQQKALSKRARGDLHPTKEELAALAAGLPLNLGASMSSIEKSLRGGSSSSSSSTPAPMTAEQDKVTLTPLNASGGGSGSSSSSAAAAGLAANLPSQTTITIAPPISSGASTSSERSERSESRISLTITNAADAAKLPPPYEEADELIIQPILKKPTAANPGSSHGGSVDDLDTAENTSAANLSGSSSSSAAAAAAAAAEENRRSSNRLKRPRSGNEQGSGSVEGQPPEKRRELRSTRHTRSSADASTLNLSTGSESGAEERNE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * *.: . . :. :: .* .:. : : *:: ..: * * . . :* . . : * . * . . . : :.. . . . .: .: .:. . * *. : ::. : . . . : . . : :: :* : . . : : * *: *. . ::: : * * :. : * * :* : * *. * . : **. * .: *. * * *:* : *:* ** : * .. : .: . .: ... : .: : : . .: ..:. * : . :* .: :. :: *. :. . . * :*.:.: :* .** .*:*:*: ::* :*:::*:.: ..* : : .* : :..* .*:* .. * * * . *** **..*: .. :: *. ** .* :****.*:.:**** :*: ::::***: * . :: .. . .* : . : : :. *..:**: :*: :*:**: *:* : :.**:****:*:**:**** : .:* : *:*: *::**: * :* ::*. ::**** *:.****:** * *: .**.. :***** ******.****:****:.*:.:: ::: .::.. : ** .. ****: : **. *.** *****:*** *.*** :****************:::: .::. *::.**::*******.**:***. **:**.:*****::*:****:** * * . *::: . **:.********::* :*: :.** :***************:.*: :::**:***:******.:.******:****:**.*: **: :**.*:***:*:***::**********:****.****:*********::******.***:*****. *: :*:***:********** ****:.****:* :::. . .:: : :: ****:**:*****:***.**:******************: ::* :******:****** ****:***.**********:************* :*:********************* * **:***: **:*****:****:*****:******. . . :*:*********:****.*:*:::: *.:*******.** **: .**:*** *****:****.** **:**::***:** *****.*:* * : .: **:. ** *.* :::. : ::.. :*.:: . *** ..: :.:::**:*** ** :***** ::*. .: ** : *** .* **::** *:***:** ***:**:*.*:*. : :**** *****:* : : :*: :* . : : *: : :*:*** ::.************:::****: .:.: ..: :: * * : .: * .*:.**:*.:*** * * ***** ***: : * .: . *:: . . .:: : * * .* :*. *. . :.: : * * .* . . . . **. . *.:****::*****.*::*::*:: : : .*: : * * * :* * : ::*.***: :* **:: :**: : . .* :*: :*:*::*:**:** *:: *::**:: . : . .:. : : * :*:*. * *: :* :*** . :* **:** *. . : *.**. :** **: .. :**: ::: *:.** :** : ::: :: .:* * : : .. :: : .. : :* . :... . : .:. * *: . . * .:..::.. ...:.:* . . *: . . .*:: . * :. * : : * ** * .** : * :*:** . : . :.: . . * . *. .: : . :. **: : * *. . . : *:.: : ::: : : : . .**: * ** :*:: *: * : : . * : : :. * . :. . .... : .. :: .. .. : : ..: : . .:. . : :.* * ::. . . ..: .. . : :.. . . ... .*. .: : . : * *. *..: : ", "identical_positions": 767, "similar_positions": 759, "identity": "13.87%" }, { "cls_id": "homologset.agr.RGD:620697", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9V2-1", "uniprot_id": "G3V9V2_RAT", "id": "G3V9V2-1", "name": "", "aln": "-------------MAAVVQQNDLVFDFASNVMEDEQQLGDPAIFPAVIVEHVPGADILNGYAGLACVEEPNDMITESSLDVAEEEIIEDDDDDITLTVEASCHNGDETIETIGAAEALLNMDSPGP-VLDEKRINNNIFSSSEDD-IVAPITHVSVTLDGIPEVMETQQVQESN--------------ADSPGASSPEQPKRKKGASLTCLGRRKTKPPRPDSPATTPNISVKKKSK-----------------DGKGNTIYLWEFLLALLQDKATCPKYIKWT-QREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEGPSSSTESSDQSLSSTTTSSRNQAN--------------------------RTRMSSSPGIKGGATTILKPGNPKVAKPKDTVEVGQPSEVLRTVQPSQAPYPTQLFRTVHVVQPVQAIPE-----EATITSTMQEEAAGSSVQG--IRTIQASTQVPVVVSPGNQQ--LHTVTLQTVPLTT----------------VIASTDPSSGAGP-------------------------------------------------------------QKFILQAIPSSQPMT---VLKEN-VLLQSQKPGSPPSIVFSPT-------------PVQQVLTGS--VQSLGNGAVSMASPPNFSATAPVVTFS-RSSQLAAHPPGTVITSVIKAQETKTPKAEVEKK-AEGHLNGDPEEIEQQPQPYVMVVSSS--NGFSSQVAITQNE--------------------LLEPSSF----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60775-1", "uniprot_id": "ELF1_MOUSE", "id": "Q60775-1", "name": "ETS-related transcription factor Elf-1", "aln": "-------------MAAVVQQNDLVFEFASNGMEDEQQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHNGDETIETIEAAEALLNIDSPSPPVLDEKQINNNIFSSSEDD-IVAPITHVSVTLDGIPEVMETQQVQETN--------------ADSPGASSPEQRKRKKG--------RKTKPPRPDSPTTTPNISVKKKNK-----------------DGKGNTIYLWEFLLALLQDKATCPKYIKWT-QREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYIDDEDPSSSIESSDQSLSSTTASSRNQAN--------------------------RSRVSSSPGIKGGAATILKPGNSKAANPKDPVEVGQPSEVLRTVQPSQAPYPTQLFRTVHVVQPVQAVPE-----EATIASTMQEEAANSSVPS--IRTIQASTQVPVVVSPGNQQ--LHTVT---VPLTT----------------VIASIDPSSGAGS-------------------------------------------------------------QKFILQTIPSSQPMT---VLKEN-VMLQSQKPGSP-SIVLSPT-------------QVQQVLTSN--VQSICNGAGSVASAPSFSATTPVVTFS-RSSQLVAHPPGTVITSVIKAQETKTLKQEVEKK-AEDDLNEDAEKSAQQPQPYVMVLSSS--NGFSSQVAVKQNE--------------------LLEPNSF----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32519-1", "uniprot_id": "ELF1_HUMAN", "id": "P32519-1", "name": "ETS-related transcription factor Elf-1", "aln": "-------------MAAVVQQNDLVFEFASNVMEDERQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIEAAEALLNMDSPGP-MLDEKRINNNIFSSPEDDMVVAPVTHVSVTLDGIPEVMETQQVQEKY--------------ADSPGASSPEQPKRKKG--------RKTKPPRPDSPATTPNISVKKKNK-----------------DGKGNTIYLWEFLLALLQDKATCPKYIKWT-QREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDPSSSIESSDPSLSSSATSNRNQTS--------------------------RSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVHVVQPVQAVPEG----EAARTSTMQDETLNSSVQS--IRTIQAPTQVPVVVSPRNQQ--LHTVTLQTVPLTT----------------VIASTDPSAGTGS-------------------------------------------------------------QKFILQAIPSSQPMT---VLKEN-VMLQSQKAGSPPSIVLGPA-------------QVQQVLTSN--VQTICNGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQEVEKKESEDHLKENTEKTEQQPQPYVMVVSSS--NGFTSQVAMKQNE--------------------LLEPNSF----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2K0-1", "uniprot_id": "A0A8M6Z2K0_DANRE", "id": "A0A8M6Z2K0-1", "name": "", "aln": "-------------MTTVVQANELVFEFASNGMDEINQLDDPSVFPAVIVEQVPAADLMQVYSGLEADEVTNGIMVDAIQDVVEENMMG----DVGLSVETPVSGGEDNMETIEAAEALLNMESPNN-ILDEKRMIHTYGNILETD-----LSYISLRPEHLSNGMDVAHDDETSS-------------LDEVPQKNFSKPARKTK-------VRKPRPARPCSPITNPSLPLKKKSK-----------------EGKGNTIYLWEFLLALLQDKNTCPKYIKWT-QREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPTDLVIIDEDDGQGDDGGAGYGGHRAAPHGRVGRG--------------------------SSRSQGRNTQVKTVKREMSPG-LNSRNGKQAEQLLQTVHVLQPNQGAAVPAQTHSVRTINMPGSVPMVLTSG--AQGGGPMTLQTLPLSSVLTNGDSSTHASPPRVILHTVPSTSPGGKDVLTIQTASLTTDSLH---------SQQLLVSTLSSSSGGV-------------------------------------------------------------ISTTPQQTASLNGITRLVTLNANGQPVVAQQPGTVIATVLKPSEYQS--------LQVKEEISDPQYFQSLVNNSPSFASFCKDEIAEGMAEMS--YRTVIINTAGQELSQSLNGHSQLASSPSEGLTPVEELEVRGEVALHPEPEAKELLESSQGLQELPVTMQIPASH--------------------FIQVKAEPTET------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11536-1", "uniprot_id": "E74EB_DROME", "id": "P11536-1", "name": "Ecdysone-induced protein 74EF isoform B", "aln": "MIMVQHLVAASAHNFASQAAASLVNVSSSSSSSSSSSSSSLSLSSSSSSSSLSSATPTPVASPVTPTSPPPAAAAPAEASPPAGAELQEDGQQAKTQEDPTMKDQDMLEKTRQEVKDPVNVEEPGAIVDTESVMARQSPSPVASTKVPESLEEISNKSPPVQEDEEESESVASDCREFKVLYNHLRQQQHHHSPSSPDKTRSTLDDVSKILWERKQQLQRSSVITAAPTLQPQQHQQPMSDIEDEETLEDVDDADADVEADAEDEELLEQYQNGYDSPLDLSLGGATSAAASAAAAASAVSRRRGRTYSGTESDDSAQCERARMRLKPERKAERSAAYKKSLMKRYYTEIPIVKQSTSPAPQQQLQQQHHLQQQQQQQPHNGSTFAGATALLHIKTEQNTLLTPLQLQQQQQQQQGLHGAAGNGGSSNGNNAHQQQQPLAIPQRPLLHNLLSGGAIHNPHHRNYTTATTGSFPPSPADSGVSDVDSSSSGGQPCADELKARLGMPPATSASAAAAAAAAAAAAAHLHTGTFLHPNLYQNNAANSLRNIWNRSVGVPDNYYGSSGAGSGGTQPGGPGNPQTPGYLTTSYFNAPTAATAAASQRGTTINGYHSLHQQQQQQQQSQQSQQQQQLAHQQLSHQQQQALHQQLSHQQQQQQQQQQQHPHSQLNGPHPHSHPHSHPHSHPHAGQHTHSTIAAAAAAAAASVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPATSSVSYDLSYMLELGGFQQRKAKKPRKPKLEMGVKRRSREGSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDIIEIDCNGV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .** :*. .. . .. :: .: . :..* : : . . . : . : : :.. . : :* .: :*::.*. : *. : . . : :* : : : . . . .. .: . ** : *. : *.: :::.: :.. :: * ** *: .* :. . . . :.***: *: . .: : .: . * : *: .. :*. .:: :.:. . : . : . . ... : : ::. : * : . . : * .. : . : .. . :.. . . . .. * * : . *:. * . * . : : *. : *: : : * . : . : : .:* . : : * ..* : . : . : : * . . : . ::: .: ", "identical_positions": 39, "similar_positions": 178, "identity": "4.42%" }, { "cls_id": "homologset.agr.RGD:620698", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7U1-1", "uniprot_id": "D4A7U1_RAT", "id": "D4A7U1-1", "name": "Zyxin", "aln": "MRREAAGGPLQSLRPRAGPGPLPGGVSCPALPPRPLPAPSPGRSLYGLGAALSPPPPSLPLRVVPPRLARSCSGPGRRVRGLGAEAVIRDAALTLLPAQPGLTMAAPRPPPAISVSVSAPAFYAPQKKFAPVVAPKPKVNPFRPGDSESPVAAGAQRAQMGRVGEIPPPPP---EDFPLPPPPVIGEGDDSE-----------GALGGAFPPPPPPLIEEPFPPAPLEEDIFPS---PPPPLEEEGGPEAPTQLPPQ-PREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATPFVPKPSTKPAPVGTAPLPP-WKAPSSSQPPPQP--QAKPQVQLHAQPQAKP------HVQ--PQSVSSANTQPR----GPLSQAPTPAP----------KFAPVAPKFTPVASKFSPGAPSGPGPQPSQKSVPLEAPSSVGTGSPQPPSFTYAQQKEKPLVQEKQHPLPPPAQNQNQVRSPGGPGPLTLKEVEELEQLTQQLMQDME-HPQRQSVAVNESCGKCSQPLARAQPAVRALGQLFHITCFTCHQCQQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGQPITDRMLRATGKAYHPHCFTCVVCACPLEGTSFIVDQANQPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKALSIEADDNGCFPLDGHVLCRKCHSARAQT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62523-1", "uniprot_id": "ZYX_MOUSE", "id": "Q62523-1", "name": "Zyxin", "aln": "-------------------------------------------------------------------------------------------------------MAAPRPPPAISVSVSAPAFYAPQKKFAPVVAPKPKVNPFRPGDSEPPVAAGAQRAQMGRVGEIPPPPP---EDFPLPPPPLIGEGDDSE-----------GALGGAFPPPPPPMIEEPFPPAPLEEDIFPS---PPPPLEEEGGPEAPTQLPPQ-PREKVCSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATPFVPKPSTKPAPGGTAPLPP-WKTPSSSQPPPQP--QAKPQVQLHVQPQAKP------HVQ--PQPVSSANTQPR----GPLSQAPTPAP----------KFAPVAPKFTPVVSKFSPGAPSGPGPQPNQKMVPPDAPSSVSTGSPQPPSFTYAQQKEKPLVQEKQHPQPPPAQNQNQVRSPGGPGPLTLKEVEELEQLTQQLMQDME-HPQRQSVAVNESCGKCNQPLARAQPAVRALGQLFHITCFTCHQCQQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGQPITDRMLRATGKAYHPQCFTCVVCACPLEGTSFIVDQANQPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHSARAQT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15942-1", "uniprot_id": "ZYX_HUMAN", "id": "Q15942-1", "name": "Zyxin", "aln": "-------------------------------------------------------------------------------------------------------MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRVGEIPPPPP---EDFPLPPPPLAGDGDDAE-----------GALGGAFPPPPPP-IEESFPPAPLEEEIFPS---PPPPPEEEGGPEAPIPPPPQ-PREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPP-WKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPR----GPPASSPAPAP----------KFSPVTPKFTPVASKFSPGAPGGSGSQPNQKLGHPEALS-AGTGSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDME-HPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARAQT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QC03-1", "uniprot_id": "F1QC03_DANRE", "id": "F1QC03-1", "name": "Zyxin", "aln": "-------------------------------------------------------------------------------------------------MSDSSSGKPIVVTSSVSLKVTAPSFYNQPKKFASVAPPRPKAQ-IAPSQPSSFVSTG----VIGRVGEVPPPPSSLSYDFPPPPPPPLDDAELPAPPPECQITHPVSDAPPSFPAPPPVAEDLHLPPPPEELTSVPSACFPPPPPPPPPVPENGAGINSQRLFEKQTSFDKQLGSLTDMLSEMETSGPFNPKLPSQFSSAPAPKPAPGPPPTAPKPALSFLPPPELQDHPSPAPWAEELRARTRPANLSTASVPAP----VQSVAKGPAVAPKTNFPPSQLNSNLASKTVSPAPSGGARGFNHTVKSPPQSTFPPPPPAAPPAPIPPPANIPKPAFNHSETSPIGSHQSFAPPSPAAPKTSPVSTFNRPAGNNVPSKVSGSGTGSGPGGAPLTMREVEELEKMTKDFIQHMDKHPPVITSPATEVCGKCGETLSRSQPAVRAMDKLFHSHCFCCVSCQRPLQGMQFYDRDGTPQCEECYMSSLSVCSRCGERITDRVLKAMGQCFHAHCFLCTTCNCSLEGAPFITDDDNKPYCVKDYHRRFSPLCVSCNEPIIPDPGSEETVRVVALEKNFHLKCYRCEDCARPLSIEADADGCYPLNGKILCMKCHTQRNKQAKQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..::*:.*:**:** ***..*..*:**.: : *.:... :.* :*****:****. *** **** .:.: . . :**.*** : :**.* * .** **** ** .* ** *:* ::.**:.:*.:* ...**:.::.* : ..*...* ..* * . : ** : .*. * .: .:: . . . * * . .. :* * . :.: :*** :* ..*.* . .*.. .. *. :: . . * *** : .: . .:. *. . . . * . .***::******::*::::*.*: ** . ...* **:* :.*:*:******:.:*** ** * .* : *** ***. :*:* ** ** .:*. *. **: ****:*:* *:.:*.:** *..* .***:.**.*: *:*:** ***::::* * *.***:*:** :********:****:***:****.:.****** :**:**:*::** ***: * : ", "identical_positions": 205, "similar_positions": 184, "identity": "28.71%" }, { "cls_id": "homologset.agr.RGD:620699", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75783-1", "uniprot_id": "RHBL1_HUMAN", "id": "O75783-1", "name": "Rhomboid-related protein 1", "aln": "MGRVEDGGTTEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPALWSRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELP-----------LDPAKLDMLVALAQ---------------SNEQGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGPLDEPGLG--VYKRFVRYVAYEILPCEVDRRWYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLR--------------FSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAVFWNVFAYDLLGAHIPPPP--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VC82-1", "uniprot_id": "RHBL1_MOUSE", "id": "Q8VC82-1", "name": "Rhomboid-related protein 1", "aln": "-----------------------------------MDRSSLLQLIQE------------------------------QQLDPENTGFIGADTFAGLVHSHELP-----------LDPTKLDMLVALAQ---------------SNERGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGLLDEPGLS--VYKRFVRYVAYEILPCEVDRRWYFYRHRTCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLR--------------FSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNVFAYDLLGADIPPPP--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88779-1", "uniprot_id": "RHBL1_RAT", "id": "O88779-1", "name": "Rhomboid-related protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLR--------------FSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFL------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6YY16-1", "uniprot_id": "A0A8M6YY16_DANRE", "id": "A0A8M6YY16-1", "name": "Rhomboid-related protein 1", "aln": "-----------------------------------MDRSSLFQLIQE-------------------------------QLDPEQTGFITVENFTSLAEHHELQ-----------LDPSKLEMLLALVQ---------------SNEHGHVCYQELIELLNSKRSSSFRRAIANGRRTLQREILLDETGLG--VYKRFVRYVAYEILPCETDRRWYFHQNRLCPPPVFMAVITIVQIMVFMCYGVMLNKWVLQTYQPDFMKSPLVYHPGHRAQIWRFFSYMFMHVGLEQLGFNALLQLMIGVPLEMVHGILRISLLYMAGVIAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMKCPYKLLRMILALVCMSSEVGRAVWLR--------------FSPPLPSSGPQPSFMAHLSGAVVGISMGLLILRSYEESLHKQCSWWVLIFSFVTFLLFAIFWNIFAYELLGVQIPPPP--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0F8-1", "uniprot_id": "Q9W0F8_DROME", "id": "Q9W0F8-1", "name": "rhomboid protease", "aln": "-------------------------------------------------------------------------MLLLSGAPSQGR----RPKNRPLIGTVE-------------EGEMPPSTVLQMPP------------APLSSKSGLVLGVCCDQLMAVQPVQRASGAAATKS------------------------NSPDWGNHRAKHHEGSAAPFKWIPP-FFIILATLLEVLVFLWVG-----------ADPPEDSLLVYRPDQRLQLWRFLSYALLHASWLHLGYNVLTQLLFGVPLELVHGSLRTGVIYMAGVLAGSLGTSVVDSEVFLVGASGGVYALLAAQLASLLLNFGQMRH--GVIQLMAVILFVFCDLGYALYS-------------RELAMHQLQTRPSVSYIAHMTGALAGISVGLLLLRQLDGGLRPRPLRWLALGVWCIFSAFGIAFNLVNTVTAQLLAEEEGQVIRQHLMNDLGMG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20350-1", "uniprot_id": "RHOM_DROME", "id": "P20350-1", "name": "Protein rhomboid", "aln": "-------------------------------------------------------------------------MENLTQNVNETKVDLGQEKEKEASQEEE-------------HATAAKETIIDIPA------------ACSSSSNSSSYDTDCSTASSTCCTRQGEHIYMQRE------------------------AIPATPLPESEDIGLLKYVHRQHWP-WFILVISIIEIAIFAYDRYTMPAQNFGLPVPIPSDSVLVYRPDRRLQVWRFFSYMFLHANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVDSEVFLVGASGGVYALLAAHLANITLNYAHMKS--ASTQLGSVVIFVSCDLGYALYT-------------QYFDGSAFAKGPQVSYIAHLTGALAGLTIGFLVLKNFGHREYEQLIWWLALGVYCAFTVFAIVFNLINTVTAQLMEEQ-GEVITQHLLHDLGVS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0E9-1", "uniprot_id": "Q9W0E9_DROME", "id": "Q9W0E9-1", "name": "", "aln": "---MWPGSERGSSRALEIPTSQQNAGGSSQQETLADIEHISTIAGSLASIGSLSHTQMRYQCTNDAGYDTEHTSLNSDFDEAELRRELLRDKWKLLFDMFDPEGFGEISVEEFLEALKSPEFLSQVPMNKRELLLERAKKAKLPTGPGYVTFQDFVNVMSGKRTRSFKCAVHHRDREVCSENDFQLVLNEPPLFRKMVHAVAMEILPEERDRKYYADRYTCCPPPFFIILVTLVELGFFVYHSVVTG--EAAPRGPIPSDSMFIYRPDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFDPDVFLVGASGGVYALLAAHLANVLLNYHQMRY--GVIKLLHILVFVSFDFGFAIYARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHLAGAIAGLTIGLLVLKSFEQKLHEQLLWWIALGTYLALVVFAIAFNIMNGFAMFNIRVEKIRVT-ETIFNDFQV-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*.. :**:* **.:*:***::** * . :*::**:**** .*: * . :**.******* :*:**.: :*: *: :: :: : :.* *:: : . *::**::**:.*:::*: :*:. : *: : : : ", "identical_positions": 47, "similar_positions": 57, "identity": "9.51%" }, { "cls_id": "homologset.agr.RGD:62070", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51673-1", "uniprot_id": "RABP2_RAT", "id": "P51673-1", "name": "Cellular retinoic acid-binding protein 2", "aln": "MPNFSGNWKIIRSENFEEMLKALGVNMMMRKIAVAAASKPAVEIKQENDDTFYIKTSTTVRTTEINFKIGEEFEEQTVDGRPCKSLVKWESENKMVCEQRLLKGEGPKTSWSRELTN--------------DGELILTMTADDVVCTRVYVRE------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22935-1", "uniprot_id": "RABP2_MOUSE", "id": "P22935-1", "name": "Cellular retinoic acid-binding protein 2", "aln": "MPNFSGNWKIIRSENFEEMLKALGVNMMMRKIAVAAASKPAVEIKQEND-TFYIKTSTTVRTTEINFKIGEEFEEQTVDGRPCKSLVKWESGNKMVCEQRLLKGEGPKTSWSRELTN--------------DGELILTMTADDVVCTRVYVRE------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29373-1", "uniprot_id": "RABP2_HUMAN", "id": "P29373-1", "name": "Cellular retinoic acid-binding protein 2", "aln": "MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGD-TFYIKTSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTN--------------DGELILTMTADDVVCTRVYVRE------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8INK3-1", "uniprot_id": "Q8INK3_DROME", "id": "Q8INK3-1", "name": "Fatty acid-binding protein, muscle", "aln": "MSFVGKKYKLDKSENFDEYMKELGVGLVTRKMGNSLS--PTVEVTLEGD-TYTLTTTSTFKTSAISFKLGVEFDEETLDGRNVKSIITLD-GNKLTQEQ---KGDKP-TTIVREFTDNELITLIPHLTPSQHGSLRLRVPCQPVPPTSVDDGARSGGCGQRPGGP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. .. ::*: :****:* :* ***.:: **:. : : *:**:. *.* *: :.*::*.:*: *.**:* **:*:*:*** **::. : **:. ** **: * *: **:*: .*.* * :..: * * * ", "identical_positions": 52, "similar_positions": 49, "identity": "31.52%" }, { "cls_id": "homologset.agr.RGD:620700", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99068-1", "uniprot_id": "AMRP_RAT", "id": "Q99068-1", "name": "Alpha-2-macroglobulin receptor-associated protein", "aln": "MAPLRDRVSTLPRLQLLVLLLLPLLLVPQPIAGHGGKYSREKNEPEMAAKRESGEE---------FRMEKLNQLWEKAKRLHLSPVRLAELHSDLKIQERDELNWKKLKVEGLDGDGEKEAKLVHNLNVILARYG----LDGRKDTQTVHSNALNEDTQ------DELGDPRLEKLWHKAKTSGKFSSEELDKLWREFLHYKEKIHEYNVLLDTLS-RAEEGYENLLSPSDMTHIKSDTLASKHSELKDRLR-----------------SINQGLDRLRKVSHQGYGPATEFEEPRVIDLWDLAQSANFTEKELESFREELKHFEAKIEKHNHYQKQLEISHQKLKHVESIGDPEHISRNKEKYVLLEEKTKELGYKVKKHLQDLSSRVSR--ARHNEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55302-1", "uniprot_id": "AMRP_MOUSE", "id": "P55302-1", "name": "Alpha-2-macroglobulin receptor-associated protein", "aln": "MAPRRERVSTLPRLQLLVLLLLPLMLVPQPIAGHGGKYSREKNEPEMAAKRESGEE---------FRMEKLNQLWEKAKRLHLSPVRLAELHSDLKIQERDELNWKKLKVEGLDKDGEKEAKLIHNLNVILARYG----LDGRKDAQMVHSNALNEDTQ------DELGDPRLEKLWHKAKTSGKFSSEELDKLWREFLHYKEKIQEYNVLLDTLS-RAEEGYENLLSPSDMAHIKSDTLISKHSELKDRLR-----------------SINQGLDRLRKVSHQGYGSTTEFEEPRVIDLWDLAQSANFTEKELESFREELKHFEAKIEKHNHYQKQLEISHQKLKHVESIGDPEHISRNKEKYVLLEEKTKELGYKVKKHLQDLSSRVSR--ARHNEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30533-1", "uniprot_id": "AMRP_HUMAN", "id": "P30533-1", "name": "Alpha-2-macroglobulin receptor-associated protein", "aln": "MAPRR--VRSFLR-GLPALLLLLLFLGPWPAASHGGKYSREKNQPKPSPKRESGEE---------FRMEKLNQLWEKAQRLHLPPVRLAELHADLKIQERDELAWKKLKLDGLDEDGEKEARLIRNLNVILAKYG----LDGKKDARQVTSNSLSGTQE------DGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLS-RTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLR-----------------SINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRSREKHALLEGRTKELGYTVKKHLQDLSGRISR--ARHNEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PJ59-1", "uniprot_id": "A0A8M1PJ59_DANRE", "id": "A0A8M1PJ59-1", "name": "", "aln": "-------------------MQLLILVSLFAVGAMAGKYSKEMNEKNASDKSNSQVE---------FRIAKLNQVWEKAIRMQLAPVRLSELHSDLKIQEKDELQWKKLKAEGMDEDGEREAKLRRNFNIILAKYG----MDGKKDTRTLDSNRLKDHEVKVG---DTFDDPKLDKLWNKARTSGKFSDEELQTLHREFQHHKDKIHEYNIVMDTVS-RTEEIHKNVISPLEG-DVKENVLHQKHTDLKQRMR-----------------DLNQGFERLRKITHEGYTDDSEFREPRVIELWEMAKRSNLSKDELDSLKEELRHFETKVEKHQHYQEQLELSHQKLKHVEALGDEDHIMRNKEKYNTLAEKAREMGYKMKKHLQDLTNKLSKNGLQHNEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VH64-1", "uniprot_id": "Q9VH64_DROME", "id": "Q9VH64-1", "name": "Alpha-2-macroglobulin receptor-associated protein", "aln": "------MVRSALVVAAIALSVLIALQGVDADKKQSKKYSKEANDPHFQQVKQEKYDPDFKSIQRPFRMAKLNLVWAKAQN-RLTEPKLKSLYMELKIHDKEEIAWKQLNSQHKDKDGLKADELRRKLIGIMSSYDLLEHFDDTQDTEKLKPYKKFHDAEERHRNKSLFKDKKLNRLWEKAEISG-FTAEELKSLKQEFDHHQDKVDVYYSLLENIGTVDTDKHENAINTEDLDTYNLISNDVNENDIKTHAQNVKSFENDLNTLRGHHTGIKDHYDRLERLVSSGP-HSQDFIEPKVQGLWRVAQASNFTVKELESIKTELHHFESRLLKLRHLHAEHALQKEKYK-------GEKVKDKSSRFEEMEDQLKKQTRKVEKLQENIEKTIFK----HTEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . . ***:* *: . :. : **: *** :* ** . :*. :* .*: :***::::*: **:*: : * ** : .* ::: *:: *. :*. :*:. : . . : * :*::**.**. ** *: ***..* :** *:::*:. * :::.:. : ::* :.. : : ...::* : : .::: :**.:: .* :* **:* ** :*: :*:: .**:::: **:***::: * .* : : : ::* : ::: . .:. : : :: .::* ::: : : *.**", "identical_positions": 77, "similar_positions": 130, "identity": "19.3%" }, { "cls_id": "homologset.agr.RGD:620701", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10867-1", "uniprot_id": "GGLO_RAT", "id": "P10867-1", "name": "L-gulonolactone oxidase", "aln": "--MVHGYKGVQFQNWAKTYGCSPEVYYQPTSVEEVREVLALAREQKKKVKVVGGGHSPSDIACTDGFMIHMGKMNRVLQVDKE----KKQITVEAGILLADLHPQLDEHGLAMSNLGAVSDVTVAGVIGSGTHNTGIKHGILATQVVALTLMTADGEVLECSESRNADVFQAARVHLGCLGIILTVTLQCVPQFHLQETSFPSTLKEVLDNLDSHLKRSEYFRFLWFPHTENVSIIYQDHTNKAPSSASNWFWDYAIGFYLLEFLLWTSTYLPC-LVGWINRFFFWMLFNCKKESSN------LSHKIFTYECRFKQHVQDWAIPREKTKEALLELK---AMLEAHPKVVAHYPVEVRFT------------RGDDILLSPCFQ-------------------------RDSCYMNIIMYRPYGKDVPRLDYWLAYETIMKKFGGRPHWAKAHN-----------------------CTQKDFEEMYPTFHKFCDIREKLDPTGMFLNSYLEKVFY----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58710-1", "uniprot_id": "GGLO_MOUSE", "id": "P58710-1", "name": "L-gulonolactone oxidase", "aln": "--MVHGYKGVQFQNWAKTYGCSPEMYYQPTSVGEVREVLALARQQNKKVKVVGGGHSPSDIACTDGFMIHMGKMNRVLQVDKE----KKQVTVEAGILLTDLHPQLDKHGLALSNLGAVSDVTVGGVIGSGTHNTGIKHGILATQVVALTLMKADGTVLECSESSNADVFQAARVHLGCLGVILTVTLQCVPQFHLLETSFPSTLKEVLDNLDSHLKKSEYFRFLWFPHSENVSIIYQDHTNKEPSSASNWFWDYAIGFYLLEFLLWTSTYLPR-LVGWINRFFFWLLFNCKKESSN------LSHKIFSYECRFKQHVQDWAIPREKTKEALLELK---AMLEAHPKVVAHYPVEVRFT------------RGDDILLSPCFQ-------------------------RDSCYMNIIMYRPYGKDVPRLDYWLAYETIMKKFGGRPHWAKAHN-----------------------CTRKDFEKMYPAFHKFCDIREKLDPTGMFLNSYLEKVFY----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54783-1", "uniprot_id": "ALO_YEAST", "id": "P54783-1", "name": "D-arabinono-1,4-lactone oxidase", "aln": "MSTIPFRKNYVFKNWAGIYSAKPERYFQPSSIDEVVELVKSARLAEKSLVTVGSGHSPSNMCVTDEWLVNLDRLDKVQKFVEYPELHYADVTVDAGMRLYQLNEFLGAKGYSIQNLGSISEQSVAGIISTGSHGSSPYHGLISSQYVNLTIVNGKGELKFLDAENDPEVFKAALLSVGKIGIIVSATIRVVPGFNIKSTQEVITFENLLKQWDTLWTSSEFIRVWWYPYTRKCVLWRGNKTTDAQNGPAKSWWGTKLGRFFYETLLWISTKIYAPLTPFVEKFVFNRQYGKLEKSSTGDVNVTDSISGFNMDCLFSQFVDEWGCPMDNGLEVLRSLDHSIAQAAINKEFYVHVPMEVRCSNTTLPSEPLDTSKRTNTSPGPVYGNVCRPFLDNTPSHCRFAPLENVTNSQLTLYINATIYRPFGCNTPIHKWFTLFENTMMVAGGKPHWAKNFLGSTTLAAGPVKKDTDYDDFEMRGMALKVEEWYGEDLKKFRKIRKEQDPDNVFLANKQWAIINGIIDPSELSD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. *:*** *...** *:**:*: ** *:: ** :*.: .**.*****::. ** :::::.::::* :. : ::**:**: * :*: *. :* ::.***::*: :*.*:*.:*:*.:. **::::* * **::...* : . . :.:**:** : :* :*:*::.*:: ** *:: .*. *::::*.: *: . **::*. *:*::.: : ::*.. ...:: :*. :* :: * *** ** : *. ::::*.* :. ::**. * . *. :* *.*.*::*. * :: *.* .*. * : :. .* *:*** : : : .* : : : *:* :***:* :.* .:: :*. * **:***** . : * * ::** .**:: ** .:** . :: ", "identical_positions": 130, "similar_positions": 175, "identity": "24.71%" }, { "cls_id": "homologset.agr.RGD:620702", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2VCW5-1", "uniprot_id": "S38A5_RAT", "id": "A2VCW5-1", "name": "Sodium-coupled neutral amino acid transporter 5", "aln": "MAISCAVGMEMQEPKMN--GTLSTGAAAGYRQEREGFLPTTHGPAPGRKPVQFLDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCASVVGIRAYEQLG--QRAFGPAGKVVVAIIICLHNVGAMSSYLFIIKSELPLVIGTFLHM-------DPEGDWFLKGNLLIILVSLLIILPLALMKHLGYLGYTSSLSLTCMLFFLISVIYKKFQ---LGCVVSHNDTVVESEP---APLQAFNSS------CEAKLFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCCPTQRRMQAVANMSIGAMFIMYGLTATFGYLTFYSTVKAEMLEMYTQEDLLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPSKAFS---------------------------------------WPRHV-AIALILLILVNILVICVPTIRDIFGFIGSTSAPSLIFILPSVFYLRIVPADMEPLFSWPKIQALCFGVLGVLFMAISLGFMFANWATGQSR-MSGH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1J0-1", "uniprot_id": "S38A5_MOUSE", "id": "Q3U1J0-1", "name": "Sodium-coupled neutral amino acid transporter 5", "aln": "MAISCAVGMEMQEPKMN--GTLSAGAAAGYRQEREGFLPTTRNPATGRKPVQFLDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCASVVGIRAYEQLG--QRAFGPAGKVVVAIIICLHNVGAMSSYLFIIKSELPLVIGTFLHM-------DPEGDWFLKGNLLIILVSLLIILPLALMKHLGYLGYTSSLSLTCMLFFLISVIYKKFQ---IGCDVSHNDTVVEAEQ---APLQAFNSS------CEAELFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPTQRRMQAVANMSIGAMFIMYGLTATFGYLTFYSTVKAEMLEMYTQEDMLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPSKAFS---------------------------------------WLRHV-AIALILLILVNILVICVPTIRDIFGFIGSTSAPSLIFILPSVFYLRIVPTEVEPLFSWPKIQALCFGVLGVLFMAISLGFMFANWATGQSR-MSGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WUX1-1", "uniprot_id": "S38A5_HUMAN", "id": "Q8WUX1-1", "name": "Sodium-coupled neutral amino acid transporter 5", "aln": "--------MELQDPKMN--GALPS-DAVGYRQEREGFLPS-RGPAPGSKPVQFMDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQLG--QRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYM-------DPEGDWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQ---LGCAIGHNETAMESEALVGLPSQGLNSS------CEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFS---------------------------------------WPRHV-AIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANWATGQSR-MSGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEJ3-1", "uniprot_id": "A0A8M2BEJ3_DANRE", "id": "A0A8M2BEJ3-1", "name": "", "aln": "METVNKMPNGHHDIPMNLEKEFTGFDALENMAEGDQFLSS---KSNGKIETQFTDFEGKTSFGMSIFNLSNAIMGSGILGLAYAMANTGIILFVFLLITIALLSSYSIHLLLRSAGVVGIRAYEQLG--YRAFGTPGKVVAGCIITLHNIGAMSSYLFIVKIELPHVIEGLTGLP------DNSGHWYVDGRYLIIIVSVCVIFPLALMKRLGYLGYTSGFSLSCMVFFLISVIYKCLSNSGIDSESNQNEKCTFSNASMISSTTEINEINSTTEICEAKLLTINPQTAFTIPIIAFAFVCHPEVLPIYTELKNPSKKQMQKVANISILAMFVMYLLTAIFGYLTFFANVDSELLKMYNKNDILMLCVRLAVLVAVTLTVPVVLFPIRRAVLQLLFPEKPFS---------------------------------------WVRHI-IIAMCLLFAVNLLVIFVPNIRDIFGFIGATSAPSLIFILPGIFYIYIVPEEQEPLKSRPKILAILFVTLGFIFMIMSITFIIIEWVNGKQS-VGGH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38176-1", "uniprot_id": "AVT5_YEAST", "id": "P38176-1", "name": "Vacuolar amino acid transporter 5", "aln": "---------------------------------------------------------MPSNVRSGVLTLLHTACGAGVLAMPFAFKPFGLMPGLITLTFCGICSLCGLLLQTRIAKYVPKSENASFAKLTQLINPSISVVFDFAIAVKCFGVGVSYLIIVGDLVPQIVQSIFYRNDDNMSGSQEHHMFLDRRLYITLIIVFVISPLCFKRSLNSLRYASMIAIVSVAYLSGLIIYHFVN----------RHQLERGQVYFMVPHGDSQSH----------------SPLTTLPIFVFAYTCHHNMFSVINEQVDKSFKVIRRIPIFAIVLAYFLYIIIGGTGYMTFGENIVGNILTLYP-NSISTTIGRLAMLLLVMLAFPLQCHPCRSSVKNIIIFIENFRKGKLYDNRASFIPLDNFNSEDPQEAPTQQNNEEPNLRSESLRHINIITLCILLFSYLLAISITSLAKVLAIVGATGSTSISFILPGLFGYKLIGSEFTGTNERVPTSIKIFKYLSLSLFIWGIAVMVASLSAIVFLGTSSH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. .::.* :: *:*:*.:.:*: *:: : * .: * .: * * . .:. : :... .** * :: .*. ***:*: :* :: : . . . ::. . * :: : :* **.: : *. * *:* ::: .: :: :**: .. .. .: . :. . *:**:.**:.** :::.: .* : : :: :. .:* : :* : . **:** .: .::* :* :. ***:*: * *:.*: .* * :: :::: : * **: *:: :*. :*.* :..: .::..:*:*.:.*: ****.:* :: : . * *.. :: .: .:. . ..*", "identical_positions": 72, "similar_positions": 163, "identity": "13.26%" }, { "cls_id": "homologset.agr.RGD:620705", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88801-1", "uniprot_id": "HOME2_RAT", "id": "O88801-1", "name": "Homer protein homolog 2", "aln": "MGEQPIFTTRAHVFQIDPSTKKNWVPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVREAAR-----------------------------------------------LARDKSQ--------EKIETSSNHSQESGCETPSSTQASSVNGTDDEKAS--------HASP-----ADTHLKSENDKLKIALTQSAANVKKWEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRSKIEELEEQCGEINRE---------KEKNTQLKRRIEELESEVREKEMELK----DLRKQSE------------IIPQLMSECEYVSEKLEAAERDNQNLED--------------------------------------------------KVRSLKTDIEESKYRQRHLKGELKSFLEVLDGKIDDLHDFRRG------------------------LSKLGTDN------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QWW1-1", "uniprot_id": "HOME2_MOUSE", "id": "Q9QWW1-1", "name": "Homer protein homolog 2", "aln": "MGEQPIFTTRAHVFQIDPSTKKNWVPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSELQLTKFAEKFQEVREAAR-----------------------------------------------LARDKSQ--------EKTETSSNHSQESGCETPSSTQASSVNGTDDEKAS--------HASP-----ADTHLKSENDKLKIALTQSAANVKKWEMELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRSKIEELEEQCSEINRE---------KEKNTQLKRRIEELESEVRDKEMELK----DLRKQSE------------IIPQLMSECEYVSEKLEAAERDNQNLED--------------------------------------------------KVRSLKTDIEESKYRQRHLKGELKSFLEVLDGKIDDLHDFRRG------------------------LSKLGTDN------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSB8-1", "uniprot_id": "HOME2_HUMAN", "id": "Q9NSB8-1", "name": "Homer protein homolog 2", "aln": "MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAK-----------------------------------------------IAKDKTQ--------EKIETSSNHSQESGRETPSSTQASSVNGTDDEKAS--------HAGP-----ANTHLKSENDKLKIALTQSAANVKKWEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRNKIDELEEQCSEINRE---------KEKNTQLKRRIEELEAELREKETELK----DLRKQSE------------IIPQLMSECEYVSEKLEAAERDNQNLED--------------------------------------------------KVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRG------------------------LSKLGTDN------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E8S7-1", "uniprot_id": "Q0E8S7_DROME", "id": "Q0E8S7-1", "name": "", "aln": "MGEQPIFTCQAHVFHIDPKTKRTWITASMKAVNVSFFYDSSRNLYRIISVEGTKAVINSTITPNMTFTQTSQKFGQWSDVRANTVYGLGFASEAELTKFVEKFQEVKEATKNAMKSANGSNAVTPTTSANTSPISGRAVGSMQNDNTAIDPHTVEPPNMSNTNTQNANPDSPSHKLLNTSDVKADIGSATPSPQPTSGVTGGGGVTISSGGSIVGMHTGPGAGATAEQQLKYENERLKMALAQSCANAKKWEIELATLKNNNIRLTSALQESTANVDEWKRQLHTYKEENIRLKRDMEQLCVGGGVVAAAGGGATEDELRREVATLKARTEQLQKELMQQELELKSANISLREKSNDQTLAKLSEVNGVFAKHLSELYGVQKDMESLIQIAKCTXDTELAFMRKVSVQEQTTMINTTTTSSTTTGSTTSKRYLSNFPTAEAESTLSNVTSIHTQLQSSLYETQNMP-QLK-ALDKHSALLQELHQRQAAPRRNSASAEAAAAGSGGAKTATILVSKSKTKTGLPLLLKNSINN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******** :****:***.**:.*:.** :**.**:*** :** ******:*:*.:************:********:* *****:****:** :****.******:**:: ::. ::* .* .:*: . : * ***. :*.*.* .. . * *:.* *: :** **::**:**:**.**.****:** **::.* ***:*****:*.*::****: ::** **: .:::* . : :.: : ** * *:*: *: ::* *** .**::*: ::.: :** *.:.:*: : : * :* *::*:::.* *. ::: :** *: .. :::**: : . :** *.. ", "identical_positions": 166, "similar_positions": 120, "identity": "31.14%" }, { "cls_id": "homologset.agr.RGD:620706", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2X5-1", "uniprot_id": "HOME3_RAT", "id": "Q9Z2X5-1", "name": "Homer protein homolog 3", "aln": "MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFGSEQQLTQFAEKFQEVKEAARLAREKSQDGGELTSTALAMASHQVP--------------------------------------------------------PSPLVSTNGP-EEKLFRS-------------QSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNQRLAGALREANAAATQWRQQLEVQRAEAEHLRQRVAELEAQVAAEPVRAGEKE--ATSQSVEQLEARVQTKDQEIQTLKNQSTGPREAPDTAEREETQQQVQDLETRNAELEQQLRAMESNLEE--------------------------------------------------ARAERERARAEVGRAAQLLDVRLFELSELREGLARLAEAAP------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JP6-1", "uniprot_id": "HOME3_MOUSE", "id": "Q99JP6-1", "name": "Homer protein homolog 3", "aln": "MSTAREQPIFSTRAHVFQIDPTTKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQQLTQFAEKFQEVKEAARLAREKSQDGGEFTSTGLALASHQVP--------------------------------------------------------PSPLVSTNGPGEEKLFRS-------------QSADTPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNQRLAGALREANAAATQWRQQLEVQRAEAELLRQRVAELEAQVAVEPVRAGEKE--ATSQSVEQLEARVQTKD---QTLKNQSTGTREAPDTAEREETQQQVQDLETRNAELEQQLRSMECNLEE--------------------------------------------------ARAERERARAEVGRAAQLLDVRLFELSELREGLARLAEAAP------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSC5-1", "uniprot_id": "HOME3_HUMAN", "id": "Q9NSC5-1", "name": "Homer protein homolog 3", "aln": "MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKSQDGGELTSPALGLASHQVP--------------------------------------------------------PSPLVSANGPGEEKLFRS-------------QSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEE--------------------------------------------------ARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAAP------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U000-1", "uniprot_id": "A0AB32U000_DANRE", "id": "A0AB32U000-1", "name": "", "aln": "---MGEQPLFSVKAHVFQIDPATKRNWIPASKHAVTVSFFFDAGRSVYRIISVGGTKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSTEQQLQQFSEQFKEFKEAARLVRDKSQEKFELLSPGLNISAPQALSVD---------------------------------------------------RQSPPLLGVNGSSEDKLFRS-------------KSADMEQTTEKEQMRKMLSEGSICEINSEAELFSLRDSNTKLVAALHDANSSIEQWKKQLAEYQEETERLREQVAELEAQSGVSAFSEMGNE--ELTQSIAEMEALIKAKDEEIKVLRNNKPDFSELEK--EKQEASQRMQDLEAKNSELEKQVETAENALAS--------------------------------------------------SKEAQSRAETAVQKAIETLDVKIYDLNDLRQNLAKLLDK--------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E8S7-1", "uniprot_id": "Q0E8S7_DROME", "id": "Q0E8S7-1", "name": "", "aln": "---MGEQPIFTCQAHVFHIDPKTKRTWITASMKAVNVSFFYDSSRNLYRIISVEGTKAVINSTITPNMTFTQTSQKFGQWSDVRANTVYGLGFASEAELTKFVEKFQEVKEATKNAMKSANGSNAVTPTTSANTSPISGRAVGSMQNDNTAIDPHTVEPPNMSNTNTQNANPDSPSHKLLNTSDVKADIGSATPSPQPTSGVTGGGGVTISSGGSIVGMHTGPGAGATAEQQLKYENERLKMALAQSCANAKKWEIELATLKNNNIRLTSALQESTANVDEWKRQLHTYKEENIRLKRDMEQLCVGGGVVAAAGGGATEDELRREVATLKARTEQLQKELMQQELELKSANISLREKSNDQTLAKLSEVNGVFAKHLSELYGVQKDMESLIQIAKCTXDTELAFMRKVSVQEQTTMINTTTTSSTTTGSTTSKRYLSNFPTAEAESTLSNVTSIHTQLQSSLYETQNMPQLKALDKHSALLQELHQRQAAPRRNSASAEAAAAGSGGAKTATILVSKSKTKTGLPLLLKNSINN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:*: :****:*** ***.**.*. :*:.**:*:*: *.:*****: *:**:****:*******:********:* **********.:* .* :* *:*:*.***:: . ..:: . .. :: . * ...* .: . :*: *.*::: *::.. : * *: :*::.* :*..**:::.: :*::** : * *:. : :* . . :.: ::* : : . : . ..::: ::.::: :: :: : : . . . : : * *: ::: .:: : * . ", "identical_positions": 93, "similar_positions": 122, "identity": "17.42%" }, { "cls_id": "homologset.agr.RGD:620707", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08423-1", "uniprot_id": "TFF1_MOUSE", "id": "Q08423-1", "name": "Trefoil factor 1", "aln": "---MEHKVICVLAVVLMLAFGSLAQAQAQAQAQEETCIMAPRERINCGFPGVTAQQCTERGCCFDDSVRGFPWCFHPMAIENTQEEECPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63467-1", "uniprot_id": "TFF1_RAT", "id": "Q63467-1", "name": "Trefoil factor 1", "aln": "---MEHKVTCVLAMVLMLALSSLAQN------QEETCAVIPRERINCGFPGVTAQQCKEKGCCFDDSVRGFPWCFRPLVIENQQEEECPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04155-1", "uniprot_id": "TFF1_HUMAN", "id": "P04155-1", "name": "Trefoil factor 1", "aln": "MATMENKVICALVLVSMLALGTLAEA------QTETCTVAPRERQNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTIDVPPEEECEF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:** *.*.:* ***:.:**: * *** : **** ********..** ::******:***.**** * .*: **** *", "identical_positions": 50, "similar_positions": 17, "identity": "55.56%" }, { "cls_id": "homologset.agr.RGD:620708", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JK79-1", "uniprot_id": "CKLF_RAT", "id": "Q9JK79-1", "name": "Chemokine-like factor", "aln": "MDSPQKVVDHQPFCLSLKCFVKTLRLVVTVASMIFFIVAQAPEPYIVITGFEVTIILFLIALYMCSLDKTMRSFFWPLLDVINSVVTTLFMLIVSVSALIPETSTMIMVGGVFGFLTVICTVADCALMCQKLRFRPHGPYQNRSATDVDDS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAS1-1", "uniprot_id": "CKLF_MOUSE", "id": "Q9DAS1-1", "name": "Chemokine-like factor", "aln": "METPRPVVSRRPFCCTLKCFVKFLRLVVTVTSMIFFIVGQAPEPYIVITGFEVTVIFCFLVLYTCGLDKIMRSFFWPLLDVINSMVTALCMLIVSVLALIPETSTKTILGGVFGFLTVTCTIADCALMCQKLRFRPRQPYQKKSTNDIDDRE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBR5-1", "uniprot_id": "CKLF_HUMAN", "id": "Q9UBR5-1", "name": "Chemokine-like factor", "aln": "MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. : :.::*** ::* .** ***.:**:** ***:.***************:*: :: ** **: *: :******:***:**:: ****** ******:* : ****.::*. * :** **: :** *.* ***::.. : .: ", "identical_positions": 79, "similar_positions": 43, "identity": "51.97%" }, { "cls_id": "homologset.agr.RGD:620709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q03404-1", "uniprot_id": "TFF2_MOUSE", "id": "Q03404-1", "name": "Trefoil factor 2", "aln": "MGPRGAPLLAVVLVLGLHALVEGEKPSPCRCSRLTPHNRKNCGFPGITSEQCFDLGCCFDSSVAGVPWCFHPLPNQESEQCVMEVSARKNCGYPGISPEDCASRNCCFSNLIFEVPWCFFPQSVEDCHY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09030-1", "uniprot_id": "TFF2_RAT", "id": "Q09030-1", "name": "Trefoil factor 2", "aln": "MGPRGAPLLVVVLVLGLHALAEGEKPSPCRCSRMTPSNRKNCGFPGITSDQCFNLGCCFDSSVAGVPWCFHPLPNQASEQCVMEVSARENCGYPGISPEDCASRHCCFSNLIFEVPWCFFPQSVDDCHY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03403-1", "uniprot_id": "TFF2_HUMAN", "id": "Q03403-1", "name": "Trefoil factor 2", "aln": "MGRRDAQLLAALLVLGLCALAGSEKPSPCQCSRLSPHNRTNCGFPGITSDQCFDNGCCFDSSVTGVPWCFHPLPKQESDQCVMEVSDRRNCGYPGISPEECASRKCCFSNFIFEVPWCFFPKSVEDCHY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.* **..:***** **. .******:***::* **.*********:***: ********:**********:* *:******* *.**********:****:*****:**********:**:****", "identical_positions": 100, "similar_positions": 21, "identity": "77.52%" }, { "cls_id": "homologset.agr.RGD:62071", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07936-1", "uniprot_id": "NEUM_RAT", "id": "P07936-1", "name": "Neuromodulin", "aln": "MLCCMRRTKQVEKNDE-DQKIEQDGVKPEDKAHKAATKIQASFRGHITRKKLK-DEKKGD--APAAEAEAKEKDDAPVADGVEKKEGDGSATTDAAPATSPKAEEPSKAGDAPSEEKKGEGDAA----------PSEEKAGSAETESAAKATTDNSPSSKAEDGPAKEEPKQADVPAAVTDAAATTPAAEDAA--KAAQPPTETAESSQAEEEKEAVDEAKPKESARQDEGKED-PEADQEHA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06837-1", "uniprot_id": "NEUM_MOUSE", "id": "P06837-1", "name": "Neuromodulin", "aln": "MLCCMRRTKQVEKNDE-DQKIEQDGVKPEDKAHKAATKIQASFRGHITRKKLK-GEKKGD--APAAEAEAKEKDDAPVADGVEKKEGDGSATTDAAPATSPKAEEPSKAGDAPSEEKKGEGDAA----------PSEEKAGSAETESAAKATTDNSPSSKAEDGPAKEEPKQADVPAAVTDAAATTPAAEDAAT-KAAQPPTETAESSQAEEEKDAVDEAKPKESARQDEGKED-PEADQEHA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17677-1", "uniprot_id": "NEUM_HUMAN", "id": "P17677-1", "name": "Neuromodulin", "aln": "MLCCMRRTKQVEKNDD-DQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLK-GEKKDD--VQAAEAEANKKDEAPVADGVEKK-GEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKESARQDEGKEEEPEADQEHA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P7P8-1", "uniprot_id": "A0A8M1P7P8_DANRE", "id": "A0A8M1P7P8-1", "name": "Neuromodulin", "aln": "MLCCIRRTKPVEKNEEADQEIKQDGIKPEENAHKAATKIQASFRGHITRKKMKDGEKEEENGEVPEEQEEEKPTDASTETQEDPKPEQPNSPANEAPPTAAADPAPS---DTPAKEEVKE---------------PQQEVEKPKEEEPSSAAADEKP---EEEGNAQKEEKEEEKPADV--------------------PEAESQETHQIDKP-DAAEESKPAEGAVSDAGTEESV-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:**** ****:: **:*:***:***::********************:* .**: : . * * :: :*.. : * : .:.:: **.*.. *. ::*::*: * .:::. ..: *..:.*::*:.* *:. *::* *: : ** * * :*: *: * :: :*.:*:** *.* .* *.*: ", "identical_positions": 79, "similar_positions": 69, "identity": "32.51%" }, { "cls_id": "homologset.agr.RGD:620710", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35233-1", "uniprot_id": "PTN2_RAT", "id": "P35233-1", "name": "Tyrosine-protein phosphatase non-receptor type 2", "aln": "------------MSATIEREFEELDAQCRWQPLYLEIRN----ESHDYPHRVAKFPENRNR--NRYRDVSPYDHSRVKLQSAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTRAVVMLNRTVEKESVKCAQYWP---TDDREMVFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGEDVNVKQILLSMRKYRMGLIQTPDQLRFSYMAIIEGAKYTKG------------------------------------------------------DSNIQKRWKELSKEDLS------------------------------------------------------PVCRHSQNRT-----MTEKYNGKRIGSEDEKLT-----GLSSK----VPDTVEESSESILRKRIREDRKATTAQKVQQMRQRLNETERKRKRWLYWQPILTKMGFVSVILVGALVGWTLLFQLNVLPRLTDT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06180-1", "uniprot_id": "PTN2_MOUSE", "id": "Q06180-1", "name": "Tyrosine-protein phosphatase non-receptor type 2", "aln": "------------MSATIEREFEELDAQCRWQPLYLEIRN----ESHDYPHRVAKFPENRNR--NRYRDVSPYDHSRVKLQSTENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRTVEKESVKCAQYWP---TDDREMVFKETGFSVKLLSEDVKSYYTVHLLQLENINTGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGCLTPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGEDVNVKQLLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKYTKG------------------------------------------------------DSNIQKRWKELSKEDLS------------------------------------------------------PICDHSQNRV-----MVEKYNGKRIGSEDEKLT-----GLPSK----VQDTVEESSESILRKRIREDRKATTAQKVQQMKQRLNETERKRKRWLYWQPILTKMGFVSVILVGALVGWTLLFH----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17706-1", "uniprot_id": "PTN2_HUMAN", "id": "P17706-1", "name": "Tyrosine-protein phosphatase non-receptor type 2", "aln": "------------MPTTIEREFEELDTQRRWQPLYLEIRN----ESHDYPHRVAKFPENRNR--NRYRDVSPYDHSRVKLQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWP---TDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKG------------------------------------------------------DSSIQKRWKELSKEDLS------------------------------------------------------PAFDHSPNKI-----MTEKYNGNRIGLEEEKLTGDRCTGLSSK----MQDTMEENSESALRKRIREDRKATTAQKVQQMKQRLNENERKRKRWLYWQPILTKMGFMSVILVGAFVGWTLFFQQNAL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W0G1-1", "uniprot_id": "PTP61_DROME", "id": "Q9W0G1-1", "name": "Tyrosine-protein phosphatase non-receptor type 61F", "aln": "MSEQKTSGSGSAAAARLQIEAEYKDKGPQWHRFYKEICETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYDHSRIVLKRGSVDYINANLVQLERAERQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHLYWPNEMGADKALKLPHVKLTVELVRLETYQNFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIPSSPNAFLKFLQQVRDSGCLSRDVGPAVVHCSAGIGRSGTFCLVDCCLVLIDKYGECNVSKVLCELRSYRMGLIQTADQLDFSYQAIIEGIKKLHDPTFLDAEEPLISNDTETHTLDELPPPLPPRVQSLNLPLAPNSGGILSLNMRAAQANGAESIGKELSKDALNNFINQHDMIHDAEVADSRPLPPLPVRAFNDSDSDEDYLLDDDDEDDTDEDEEYETINEHDADPVNGHVPATTQPHADDVNANNEKPAVPVDEQHKANGIDPIPGQLPASPENELKRRKRNEYQASLEQKVNDMKRKQRENEDKQ------LAAKKRRSLLTYIAAGVVVGVICAYAYTKLG-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :: * * * :*: :* ** : *::: . .:: .: ** ******.******: *: . *****.**::*.*:*.******** :* *******:**::**:***: :**:.:** *** *: : : .. ::*:*: :. . :. : ::* :::: ::* : :**********:*.** :**:** :**:**.*. * ****:************.*** ****::* : *:.::* .:*.********.*** *** ***** * :. .. :. *****: *. . *. : . : :.. :. ::** : :: : . : ..*. *::* *:: :*: ***::*::: .*.* *: . .: .::: * .*..** : ", "identical_positions": 163, "similar_positions": 137, "identity": "29.16%" }, { "cls_id": "homologset.agr.RGD:620711", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7Y0-1", "uniprot_id": "G3V7Y0_RAT", "id": "G3V7Y0-1", "name": "Hedgehog protein", "aln": "---------------------------------------------------------MALPASLLPLCCLALLAL-----SVQSCGPGRGPVGRRRYVRKQLVPLLYKQFVPSMPERTLGASGPAEGRVTRGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRNHIHVSVKADNSLAVRAGGCFPGNATVRLRSGERKGLRELHRGDWVLAADAAGRVVPTPVLLFLDRDLQRRASFVAVETERPPRKLLLTPWHLVFAARGPAPAPGDFAPVFARRLRAGDSVLAPGGD--ALRPARVARVAREEAVGVFAPLTAHGTLLVNDVLASCYAVLESHQWAHRAFAPLRLLHALGALLPG------------GAVQPTGMHWYSRLLYRLAEELMG------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61488-1", "uniprot_id": "DHH_MOUSE", "id": "Q61488-1", "name": "Desert hedgehog protein", "aln": "---------------------------------------------------------MALPASLLPLCCLALLAL-----SAQSCGPGRGPVGRRRYVRKQLVPLLYKQFVPSMPERTLGASGPAEGRVTRGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRNHIHVSVKADNSLAVRAGGCFPGNATVRLRSGERKGLRELHRGDWVLAADAAGRVVPTPVLLFLDRDLQRRASFVAVETERPPRKLLLTPWHLVFAARGPAPAPGDFAPVFARRLRAGDSVLAPGGD--ALQPARVARVAREEAVGVFAPLTAHGTLLVNDVLASCYAVLESHQWAHRAFAPLRLLHALGALLPG------------GAVQPTGMHWYSRLLYRLAEELMG------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43323-1", "uniprot_id": "DHH_HUMAN", "id": "O43323-1", "name": "Desert hedgehog protein", "aln": "---------------------------------------------------------MALLTNLLPLCCLALLAL-----PAQSCGPGRGPVGRRRYARKQLVPLLYKQFVPGVPERTLGASGPAEGRVARGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRNHVHVSVKADNSLAVRAGGCFPGNATVRLWSGERKGLRELHRGDWVLAADASGRVVPTPVLLFLDRDLQRRASFVAVETEWPPRKLLLTPWHLVFAARGPAPAPGDFAPVFARRLRAGDSVLAPGGD--ALRPARVARVAREEAVGVFAPLTAHGTLLVNDVLASCYAVLESHQWAHRAFAPLRLLHALGALLPG------------GAVQPTGMHWYSRLLYRLAEELLG------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02936-1", "uniprot_id": "HH_DROME", "id": "Q02936-1", "name": "Protein hedgehog", "aln": "MDNHSSVPWASAASVTCLSLDAKCHSSSSSSSSKSAASSISAIPQEETQTMRHIAHTQRCLSRLTSLVALLLIVLPMVFSPAHSCGPGRG-LGRHR--ARNLYPLVLKQTIPNLSEYTNSASGPLEGVIRRDSPKFKDLVPNYNRDILFRDEEGTGADRLMSKRCKEKLNVLAYSVMNEWPGIRLLVTESWDEDYHHGQESLHYEGRAVTIATSDRDQSKYGMLARLAVEAGFDWVSYVSRRHIYCSVKSDSSISSHVHGCFTPESTALLESGVRKPLGELSIGDRVLSMTANGQAVYSEVILFMDRNLEQMQNFVQLHTDGG-AVLTVTPAHLVSVWQ---PESQKLTFVFADRIEEKNQVLVRDVETGELRPQRVVKVGSVRSKGVVAPLTREGTIVVNSVAASCYAVINSQSLAHWGLAPMRLLSTLEAWLPAKEQLHSSPKVVSSAQQQNGIHWYANALYKVKDYVLPQSWRHD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .* .* *:.* ..:******* :**:* ::* **: ** :*.:.* * .**** ** : *.* :*:******* **:*:***.:******::****::*.** :*** ***:** ***.**** **.*:********: *:*****:.***:************* * **.*:: ***:*.*:: :. ***. ::*. * ** ** * ** ** **: * *:.* : *:**:**:*:: .** :.*: * :** *** . : * . .:: *** *:. :.**. . : *:* **.:*. .: **.**** .**::**.* ******::*:. ** .:**:*** :* * **. .* * .*:***:. **:: : :: ", "identical_positions": 198, "similar_positions": 111, "identity": "41.42%" }, { "cls_id": "homologset.agr.RGD:620712", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6B9-1", "uniprot_id": "G3V6B9_RAT", "id": "G3V6B9-1", "name": "Tyrosine-protein phosphatase non-receptor type", "aln": "MTARFRLP-AGRTYNVR--ASELARDRQ--HTEVVCNILLLDNTVQAFRVNKHDQGQVLLDIVFKHLDLTERDYFGLQLADDSTDNPRWLDPNKPIRKQLKKLFLLILGGSPYNLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLSCPCNTAALLASFAVQSELGDYNQSENLAGYLSDYSFIPNQPQDFEKEIAKLHQQHIGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEILIGVMSGGILIYKNRVRMNTFLWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKTLWKACVEHHTFFRLDRPLPPQKNFFAHYFTLGSKFRYCGRTEVQSVQYGKEKANKDRVFARSPSKPLARKLM---DWEVVSRNSLSDDRLETQSLPSRSPPGTPNHRNSSFTQEGTRVRPSSVGHLVDHVVHTSPSE-DFVSQRSPSSTQANSIVLES---SPSQETPEDGQPPALPPKQSKKNSWNQIHFSHSQQDLVNHTNESFDVPSSPEKSTPNGGIPHDNLVLIKMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLFIKASCERHSGELVLLVRPNAVYDVVEEKLESEPDFQYIPEKAPLDSVH---QDDHSLRESMIQLAEGLITGTVLAQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVLLKG--NEDYINANYINMEISSSSIINQYIACQGPLPHTCKDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEP-SGSSSYGCYQVTCHSE--EGNPAYIFRKMTLFNQEKNESRQLTQIQYTAWPDHGVPDDSSDFLDFVCHVRNKR---------------------AGKEE-------------------------------------PIIVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYEEGFVKPLTTSSNK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WU22-1", "uniprot_id": "PTN4_MOUSE", "id": "Q9WU22-1", "name": "Tyrosine-protein phosphatase non-receptor type 4", "aln": "MTARFRLP-AGRTYNVR--ASELARDRQ--HTEVVCNILLLDNTVQAFRVNKHDQGQVLLDIVFKHLDLTERDYFGLQLADDSTDNPRWLDPNKPIRKQLKR-------GSPYNLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLSCPCNTAALLASFAVQSELGDYNQSENLAGYLSDYSFIPNQPQDFEKEIAKLHQQHVGLSPAEAEFNYLNAARTLELYGVEFHYARDQSNNEILIGVMSGGILIYKNRVRMNTFLWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKTLWKACVEHHTFFRLDRPLPPQKNFFAHYFTLGSKFRYCGRTEVQSVQYGKEKANKDRVFARSPSKPLARKLM---DWEVVSRNSLSDDRLETQSLPSRSPPGTPNHRNSSFTQEATRVRPSSVGHLVDHVVHMSPSE-DFVSQRSPSSTQANSIVLES---SPSQETPEDGQPPALPPKQSKKNSWNQIHFSNSQQDLVTHTNESFDVPSSPEKSTPNGGIPHDNLVLIKMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLFIKASCEKHSGELVLLVRPNAVYDVVEEKLESEPDFQYIPEKAPLDSVH---QDDHSLRESMIQLAEGLITGTVLAQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVLLKG--NEDYINANYINMEIPSSSIINQYIACQGPLPHTCKDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEP-SESSSYGCYQVTCHSE--EGNPAYIFRKMTLFNQEKNESRQLTQIQYTAWPDHGVPDDSSDFLDFVCHVRDQR---------------------AGKEE-------------------------------------PIIVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYEEGFVKPLTTSSNK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29074-1", "uniprot_id": "PTN4_HUMAN", "id": "P29074-1", "name": "Tyrosine-protein phosphatase non-receptor type 4", "aln": "MTSRFRLP-AGRTYNVR--ASELARDRQ--HTEVVCNILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADDSTDNPRWLDPNKPIRKQLKR-------GSPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLPCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQPQDFEKEIAKLHQQHIGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYKNRVRMNTFPWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHTFFRLDRPLPPQKNFFAHYFTLGSKFRYCGRTEVQSVQYGKEKANKDRVFARSPSKPLARKLM---DWEVVSRNSISDDRLETQSLPSRSPPGTPNHRNSTFTQEGTRLRPSSVGHLVDHMVHTSPSE-VFVNQRSPSSTQANSIVLES---SPSQETPGDGKPPALPPKQSKKNSWNQIHYSHSQQDLESHINETFDIPSSPEKPTPNGGIPHDNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLFIKASCERHSGELMLLVRPNAVYDVVEEKLENEPDFQYIPEKAPLDSVH---QDDHSLRESMIQLAEGLITGTVLTQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVILKG--NEDYINANYINMEIPSSSIINQYIACQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEP-TGSSSYGCYQVTCHSE--EGNTAYIFRKMTLFNQEKNESRPLTQIQYIAWPDHGVPDDSSDFLDFVCHVRNKR---------------------AGKEE-------------------------------------PVVVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYEEGFVKPLTTSTNK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U039-1", "uniprot_id": "A0AB32U039_DANRE", "id": "A0AB32U039-1", "name": "Tyrosine-protein phosphatase", "aln": "MTARFRLP-AGRSYNVR--TTELARDRQ--RTEVVCNILLLDNTVQPFKVNKHDQGQILLDAVFKHLELTERDYFGLHLADEPSDSPRWLDPNKPIRKQLKR-------GSPHHLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILSGRLPCPHNTAALLASYAVQSELGDYSEAENLPGYLSEFFFIPNQPQGFEKDVAKHHQQHNGLNPAQSEFNYLNTARTLDLYGVELHYARDQSNTEIYVGVLSAGIGIYKNRVRINYFPWLKIVKISFKCKQFFIQLRKEAHDTRDTLLGFNMVNYRACKNLWKTCVEHHTFFRLDRPVPPQKNFFAHYFSLGSRFRYCGRTEAQSVQYGKEKGIKDRVFARSPSKPLARKLMGVTDWEAVSRNSLSEERLETRSLPTRSPPGTPNH-NSLFVQEGPRLRPSSMGHLVDHVIHASPSLPVFSNHKSASSTQANSISLES---TPSPEGVE-GPPPALPPKQSRKN-LSQLILSHSQQDLDNHINEMYDVPTATDKVMPNGVVPHDNLVLIKMKPDENGRFGFNVKGGSDQKMPIIVSRVAPGTSADLCVPRLNEGDQVVLINGREIAEHSHDQVVMFIKASCESHSGELILLVRPNAIYDVVEEKLETEPDFQYIPEKSPTDPSH---LDQDAWRDSMLYLKEGLNSGTILAQFDQLYRKRPGMTMSCAKLPQNISKNRYRDISPYDATRVILKG--TEDYINANYINMEIPACSLINRYIACQGPLPNTCSDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPNP-SGSATYGGFQISCQTE--EGNSAFLVREITLTHIESGESRELTQIQYLAWPDHGVPDDSTDFLDFVALVRNKR---------------------AGKDE-------------------------------------PVVVHCSAGIGRTGVLITMETAMCLMECSQPVFPLEIVRTMRDQRAMMIQTPSQFKFVCEAILKVYEEGLVKPLKSILYESN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0R3-1", "uniprot_id": "Q9W0R3_DROME", "id": "Q9W0R3-1", "name": "Tyrosine-protein phosphatase", "aln": "MFERFRLNNLTRTFRLRGGGPELARDKKTPQRQQCVTVLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLFPQKPGDVVRWVDAQKQFKKQCSSVSLDN--DAVPLLEFRVKFFVSDPSRLQEEFTRYQFYLQIKRNILLGKLPCSSNTQCLLASYTVQSELGDFNALEHQPGYLSGMQLLCDQTTEAERKVGELHKLHRGQLPADAEYNYLEHAKRLELYGIDLHRATDSNGKELQLGVSAVGLLVFQHSLRVNTFSWSKMVKVSFKRKDFFIQLRREPSENYDTLLGFGMSSHKHAKALWKSCVEHHSFFRLKRPHRLSR-FLN--ISLGSKFYYSGRTELQAVQESKQRGRIHKVFVRSPSKRLLGAAG------GVGTSGSSGGTPMQQHSGSESAN---SHNNGKPAGAGTILTITKTSRPHDNKVTSKEAD-SMPRKAWEQQSDEYDIQLDVGFIEQCTRRFESASPSPMPPAYSSGQ-HSPILLPTTIADAVGHQ--------QPESGS--------DLITIRLQADEQGRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTVRP---QRSAPLLLEEEPLYQYVPESDEIGSHSNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMEIPG-GAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLK--DKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATPEDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYMKISRSSAAINDDED-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **** *::.:* .*****:: : : .:*:**: .:.*:::*: :*. *** **::*:*:*:***** :.:.. * **:*.:* ::** . .: *:**********.:****:****::****::** *:*.*. ** .****::*******:. *: .**** :: :*. *:.:.: *: * * **::*:***: *: *:***:::* * *....*: :** : *: :::: :*:* * * *:**:*** *:******:* :. :*****.* .:: .* ***:*****:****.** .: *: ::***:* *.**** *:** .*::. .:**.***** * *. .. * : :.*. .* *. . .. : :. .: *: : . : : : ..:: .* *: . . . *..:** * : . : . : * * .:. :*: *:::.**:**:******* * .:*: **:*.* *.** *.**: ***:*::****:: *:*** :*: . . ****:* *** . ** ** :**:**. .. .: :*:: * :** :*::*:*:: :***.*.:::: *: * * .***********.*** * . . *******:****.. . :*:*** ****. * .***:*. ::.* ::***** :* ** ******* . :.: * :* : . :::.*::.* :. *.* : ::** ***** **.*.. **:*. ** * *. :* *::************** *:**:.*:*. :**:**:********** *:*. **::****.* .* : .. : ", "identical_positions": 373, "similar_positions": 284, "identity": "36.82%" }, { "cls_id": "homologset.agr.RGD:620713", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04589-1", "uniprot_id": "FGFR1_RAT", "id": "Q04589-1", "name": "Fibroblast growth factor receptor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MWGWRGLLFWAVLVTATLCTARPAPTLPEQAQPWGVPVEVESLLVHPGDLLQLRCRLRDDVQSINWLRD-------------------------------------------GVQLAESNRTRITGEEVEVRDSI-------------------------------PADSGLYACVTNSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRRPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPSPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYDQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALE-----ERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAG-------VSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPS-------HNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPNPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQRPTFKQLVEDLDRIVALTS---NQEYLDLSMPLD-QDSPSFPDTRSSTCSSGEDSVFSHEPFPEEPCLPRHPTQLANG-GLNRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16092-1", "uniprot_id": "FGFR1_MOUSE", "id": "P16092-1", "name": "Fibroblast growth factor receptor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MWGWKCLLFWAVLVTATLCTARPAPTLPEQAQPWGVPVEVESLLVHPGDLLQLRCRLRDDVQSINWLRD-------------------------------------------GVQLVESNRTRITGEEVEVRDSI-------------------------------PADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRRPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALE-----ERPAVMTSPLYLEIIIYCTGAFLISCMLGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAG-------VSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPS-------HNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS---NQEYLDLSIPLD-QYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPTQLANS-GLKRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11362-1", "uniprot_id": "FGFR1_HUMAN", "id": "P11362-1", "name": "Fibroblast growth factor receptor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRD-------------------------------------------GVQLAESNRTRITGEEVEVQDSV-------------------------------PADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALE-----ERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAG-------VSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPS-------HNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS---NQEYLDLSMPLD-QYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANG-GLKRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90Z00-1", "uniprot_id": "FGR1A_DANRE", "id": "Q90Z00-1", "name": "Fibroblast growth factor receptor 1-A", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMMMIMKTTLLLISVLLTQALQSQGRPAIQDEAP-----AEPTSYTLDSGEKLELSCKAKEDTQKVTWTKD-------------------------------------------LVPLVDGEHTRLRNDQMEIEKVE-------------------------------PTDSGLYACFAQGLNSNHTEYFNISVT-------DEEDEVDSSSEEAKLSNDQ--NLPMAPVWAQPDKMEKKLHAVPASKTVKFRCQANGNPTPTLKWLKNGKEFKRDQRIGGFKVREHMWTIIMESVVPSDRGNYTCLVENRHGSINHTYQLDVVERSPHRPILQAGLPANRTAVVGSDVEFECKVFSDPQPHIQWLKHIEVNGSRYGPDGLPYVRALKTAGVNTTDKEMEVLQIRNVSLEDAGEYTCLAGNSIGHSHHSAWLTVYKA-------VPPTQLPNQTYLEVLIYCVGFFLICVMVGTAVLAKMHSSAKKSDFNSQLAVHKLAKSIPLRRQVTVSVDSSSSMHSGGMLVRPSRLSSSGSPMLSG-------VSEYELPQDPRWEVQRDRLVLGKPLGEGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPD-------QVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQRPTFKQLVEDLDRTLSMTS---NQEYLDLSVSLD-QFSPNFPDTRSSTCSSGEDSVFSHDAGADEPCLPKFPPHPNRGVAFKKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NUM7-1", "uniprot_id": "A0A8M1NUM7_DANRE", "id": "A0A8M1NUM7-1", "name": "Fibroblast growth factor receptor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MIFLSAAVSLRMLKSWRLLVLLLILTQLCTVQSRPAVTEQG------------------------------------------------------------------------------------------------------------------------------------------------------------HIVASS-------EDEDDDESSSEENKPSSSQE-LLPMAPRWAQPEKMEKKLHAVPASKTVKFRCQAEGNPIPKLRWLKNGKEFKRDQRIGGYKLREHMWTIIMESVVPSDKGNYTCLVENEYGSINHTYQLDVVERSPHRPILYAGLPANRTAVVGSDVEFVCKVFSDPQPHIQWLKHIRVNGSQLGPDGLPYVRVLKTAGLNTTDKEMEVLQLRNVSFEDAGEYTCLAGNSIGISHHSAWLTVVKAP------TAPSAVPSQSYLEVLIYCIGFFLIFLMVGIATIVKIRSSSKKSDFNSQLAVHKLAKSIPLRRQITVSVESSSSLNSGVMLVRPSRLSSSGTPMLSG-------VSEYELPQDPCWEVSRERLVLGKPLGEGCFGQVVMGEAIGLDKDKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEFASKGNLREYLRARRPHGMEYCYNPD-------PLPIESMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP-VEELFKLLREGHRMDKPSACTQELYLMMKDCWHAVPTQRPTFKQLVEDLDRTLSLIS---NQEYLELSVPLEPMYSQVILNERSSTCSSEQDSVFLQEPGPEDPCIPPSQ-QPMR--SFKKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07407-1", "uniprot_id": "FGFR1_DROME", "id": "Q07407-1", "name": "Fibroblast growth factor receptor homolog 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAWSWRASHSTITMTSGSLVVLFLLLSIWQP------------AVQVEGRRQMANSQEMIK--------------------------------------------------DHLGARSQNK-----------------------------------------------------TPAITNNANQSSTSSAD---LDDGAADDDDNKADLPVNVSS----KPYWRNP-KKMSFLQTRPSGSLLTLNCHALGNPEPNITWYRNG---TVDWTRGYGSLKRNRWTLTMEDLVPGDCGNYTCKVCNSLGCIRHDTQVIVSDRVNHKPILMTG-PLNLTLVVNSTGSMHCKYLSDLTSKKAWIFVPCHGMTN------------CSNNRSIIAEDKDQLDFVNVRMEQEGWYTCVESNSLGQSNSTAYLRVVRSLHVLEAGVASGSLHSTSFVYIFVFGGLIFIFMT-TLFVFYAIRKMKHEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGSMDTMIMPVVRIQKQRTTVLQNGN---EPAP-FNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAEVN---------NAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSS---QPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTK-----EDYLDVDIANL----------DTPPSTSDEEED-------ETDNLQKWCNY----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q09147-1", "uniprot_id": "FGFR2_DROME", "id": "Q09147-1", "name": "Fibroblast growth factor receptor homolog 2", "aln": "MAKVPITLVMIIAIVSAAADLGCDYGHHRCYIDVTVENSPRQRHLLSDMDITLQCVRPMAKWFYEDKFQLRATLLRLERAQSGNSGNYGCLDSQNRWYNISLVVGHKEPVGNDIASFVKLEDAPALPESDLFFQPLNESRSLKLLQPLPKTVQRTAGGLFQLNCSPMDPDAKGVNISWLHNDTQILGGRGRIKLKRWSLTVGQLQPEDAGSYHCELCVEQDCQRSNPTQLEVISRKHTVPMLKPGYPRNTSIALGDNVSIECLLEDSALEPKITWLHKGNADNIDDLLQRLREQSQLPVDVTRLITRMDEPQVLRLGNVLMEDGGWYICIAENQVGRTVAASYVDLYSPSDTTTVRTTTTTTVASPIPTASTGEDNDDDVENPAAEASGGVGPPVFR---KELKRLQHSLSGNTVNLACPVYG--KANITWTKD----KKPLNRELGVYVQKNWTLRFVEATSEDSGLYNCKVCNAWGCIQFDFSVQINDRTRSAPIIVV--PQNQTVKVNGSLVMKCTVYSDLHPTVSWKRVVLKNASLDGLK-----SVEIQNLNFTVTNDSVVLTLRNVTFDQEGWYTCLASSGLGRSNSSVYLRVVSPLPPLEI---YALLHAHPLGFTLAAITIVALFLLGSAFITFMLRRLRREKLLKLRIETVHQWTKKVIIYRPGGEEGSGCSSGDLQMPVIRIEKQRTTVSTTGTGGTDPAQGFNEYEFPLDSNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQASSNPNDAYLDLSMPML----------ETPPSSGDEDDGSDTETFRETSPLRYQYTYKFN-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . :...:. . * : * . *: :.. :.: * * ..: * :: . *:: : . .. * * *.* * * *.*.. .: : :* **: . * * * :.. : *. ** . * . : :: * : ** ::: * ***: ...:* *: :.:* * . : : :: : :* :**: :*.: : : .. : ::* .: :: ..***:* *. **: *.:* ** ****.**:*::.*. : *****:*. *: *::.*: ***:**:**:* *******.*:*.***:****:*.:***:::* .** . : :.. . . : *:* . *.*:****:****::*************::. *:**********:: :**:*.******:******:* :: * :*****:*:*****:* * .* * : .***:. * *:**::*: *: ::*::*::**: . **.* ::** :* : : **::.:. :...:. ::. : : ", "identical_positions": 189, "similar_positions": 195, "identity": "17.37%" }, { "cls_id": "homologset.agr.RGD:620714", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LSN4-1", "uniprot_id": "F1LSN4_RAT", "id": "F1LSN4-1", "name": "Fibroblast growth factor receptor", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVVPACVLVFCVAV--VAGVTSEPPGPEQRVGRR-----------AAEVPGPEPSQQEQVAFG-------------------SGDTVELSCHPPGGAPTGPTLWAKDG-----VGLVASHRILVG--------------PQRLQVLNATHEDAG----------------------VYSCQQRLTRRVLCHFSVRVTDAPSSGDDED-GEDVAEDT----GAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDRELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELMEVDEAGSVYAGVLSYG---VGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKVSRFPLKRQQVSLES--NSSMNSNTPLVRIARLSSGEGPVLANVS----------ELELPADPKWELSRTRLTLGKPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGMDYSFDACR-------LPEEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRILTVTS---TDEYLDLSVPFEQYSPGGQDTPSSSSSGDDSVFTHDLLPPGP------PSNGGPRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61851-1", "uniprot_id": "FGFR3_MOUSE", "id": "Q61851-1", "name": "Fibroblast growth factor receptor 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVVPACVLVFCVAV--VAGATSEPPGPEQRVVRR-----------AAEVPGPEPSQQEQVAFG-------------------SGDTVELSCHPPGGAPTGPTVWAKDG-----TGLVASHRILVG--------------PQRLQVLNASHEDAG----------------------VYSCQHRLTRRVLCHFSVRVTDAPSSGDDED-GEDVAEDT----GAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAILGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELMETDEAGSVYAGVLSYG---VVFFLFILVVAAVILCRLRSPPKKGLGSPTVHKVSRFPLKR-QVSLES--NSSMNSNTPLVRIARLSSGEGPVLANVS----------ELELPADPKWELSRTRLTLGKPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGMDYSFDACR-------LPEEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPSPYPGIP-VEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRILTVTS---TDEYLDLSVPFEQYSPGGQDTPSSSSSGDDSVFTHDLLPPGP------PSNGGPRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22607-1", "uniprot_id": "FGFR3_HUMAN", "id": "P22607-1", "name": "Fibroblast growth factor receptor 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAPACALALCVAVAIVAGASSESLGTEQRVVGR-----------AAEVPGPEPGQQEQLVFG-------------------SGDAVELSCPPPGGGPMGPTVWVKDG-----TGLVPSERVLVG--------------PQRLQVLNASHEDSG----------------------AYSCRQRLTQRVLCHFSVRVTDAPSSGDDED-GEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYG---VGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKR-QVSLES--NASMSSNTPLVRIARLSSGEGPTLANVS----------ELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCK-------PPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTS---TDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAP------PSSGGSRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I8X3-1", "uniprot_id": "FGFR3_DANRE", "id": "Q9I8X3-1", "name": "Fibroblast growth factor receptor 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVPLCLLLYLATLVFPPVYSAHLLSPEP----------------TDWVSSEVEVFLEDYVAG-------------------VGDTVVLSCTP--QDFLLPIVWQKDG-----DAVSSSNRTRVG--------------QKALRIINVSYEDSG----------------------VYSCRHAHKSMLLSNYTVKVIDSLSSGDDEDYDEDEDEAGNGNAEAPYWTRSDRMEKKLLAVPAANTVKFRCPAAGNPTPSIHWLKNGKEFKGEQRMGGIKLRHQQWSLVMESAVPSDRGNYTCVVQNKYGSIKHTYQLDVLERSPHRPILQAGLPANQTVVVGSDVEFHCKVYSDAQPHIQWLKHIEVNGSQYGPNGAPYVNVLKTAGINTTDKELEILYLTNVSFEDAGQYTCLAGNSIGYNHHSAWLTVLPAVEMEREDD-----YADILIYV---TSCVLFILTMVIIILCRMWINTQKTLPAPPVQKLSKFPLKR-QVSLES--NSSMNSNTPLVRIARLSSSDGPMLPNVS----------ELELPSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCK-------IPNETLTFKDLVSCAYQVARGMEYLASKKCIHRDPAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGG-SPYPGIP-VEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRVLSMTS---TDEYLDLSVPFEQYSPTCPDSNSTCSSGDDSVFAHDPLPEEPCLPKHHHSNGVIRT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07407-1", "uniprot_id": "FGFR1_DROME", "id": "Q07407-1", "name": "Fibroblast growth factor receptor homolog 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAWSWRASHSTITMTSGSLVVLFLLLSIWQP------------AVQVEGRRQMANSQEMIK--------------------------------------------------DHLGARSQNK-----------------------------------------------------TPAITNNANQSSTSSAD---LDDGAADDDDNKADLPVNVSS----KPYWRNPKKMSF-LQTRPSGSLLTLNCHALGNPEPNITWYRNGTVDWT-RGYG--SLKRNRWTLTMEDLVPGDCGNYTCKVCNSLGCIRHDTQVIVSDRVNHKPILMTG-PLNLTLVVNSTGSMHCKYLSDLTSKKAWIFVPCHGMTN------------CSNNRSIIAEDKDQLDFVNVRMEQEGWYTCVESNSLGQSNSTAYLRVVRSLHVLEAGVASGSLHSTSFVYIFVFGGLIFIFMT-TLFVFYAIRKMKHEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGSMDTMIMPVVRIQKQRTTVLQNGN---EPAP-FNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAEVN---------NAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSS---QPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQ-QPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTK-----EDYLDVDIANLDTPPSTSDEEED---------ETDNLQKWC-------NY-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q09147-1", "uniprot_id": "FGFR2_DROME", "id": "Q09147-1", "name": "Fibroblast growth factor receptor homolog 2", "aln": "MAKVPITLVMIIAIVSAAADLGCDYGHHRCYIDVTVENSPRQRHLLSDMDITLQCVRPMAKWFYEDKFQLRATLLRLERAQSGNSGNYGCLDSQNRWYNISLVVGHKEPVGNDIASFVKLEDAPALPESDLFFQPLNESRSLKLLQPLPKTVQRTAGGLFQLNCSPMDPDAKGVNISWLHNDTQILGGRGRIKLKRWSLTVGQLQPEDAGSYHCELCVEQDCQRSNPTQLEVISRKHTVPMLKPGYPRNTSIALGDNVSIECLLEDSALEPKITWLHKGNADNIDDLLQRLREQSQLPVDVTRLITRMDEPQVLRLGNVLMEDGGWYICIAENQVGRTVAASYVDLYSPSDTTTVRTTTTTTVASPIPTASTGEDNDDDVENPAAEASGGVGPPVFR--KELKR-LQHSLSGNTVNLACPVYG--KANITWTKD-KKPLN-RELG--VYVQKNWTLRFVEATSEDSGLYNCKVCNAWGCIQFDFSVQINDRTRSAPIIVV--PQNQTVKVNGSLVMKCTVYSDLHPTVSWKRVVLKNASLDGLK-----SVEIQNLNFTVTNDSVVLTLRNVTFDQEGWYTCLASSGLGRSNSSVYLRVVSPLPPLEI---YALLHAHPLGFTLAAITIVALFLLGSAFITFMLRRLRREKLLKLRIETVHQWTKKVIIYRPGGEEGSGCSSGDLQMPVIRIEKQRTTVSTTGTGGTDPAQGFNEYEFPLDSNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGD-QPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGILQQASSNPNDAYLDLSMPMLETPPSSGDEDDGSDT--ETFRETSPLRYQY-------TYKFN--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . : : : :. *::: : * : ..:. * :.. : : * . * ..* * :: : * ::.*:* : . .. * * *.* * * *.*: : : :* **: . * * * :.. ::*. ** . * . : .: * : ** ::: * ***: ...:* .: :.:* *: . :: : : . ::: . : :: : :..: ::. * . .:. . . : : *:.. . . . * *:* *.:**:.* :* ** ****.**:*****. *****:*: ** *::.** ***:**:**:* *******.*:*.***:*:****.:***:::* .** . : *: . . : *:* . *.*:****:****::***** *******::. *:**********::. :**:*.******:******:* :: * :*****:*:*****:* * .*** * .***:. * *:**:***.*: ::*::**:*** . **.* ::** * :* : ***:. . : .* * . . * . ", "identical_positions": 203, "similar_positions": 192, "identity": "18.74%" }, { "cls_id": "homologset.agr.RGD:620715", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62976-1", "uniprot_id": "KCMA1_RAT", "id": "Q62976-1", "name": "Calcium-activated potassium channel subunit alpha-1", "aln": "MANGGGGGGGGSSGSSGGGGGGGGGETALRMSSNIHANHLSLDASSSSSSSSSSSSSSSSS-----VHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINN-GSSQADGTLKPVDEKEEVVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSS-NPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIK-IEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRSRKRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRR----------------------------------------------------------LEDEQPPTLSPKKKQR-------NGGMRNSPNTSP---------KLMRHDPLLIPGNDQID------------------------------------------NMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELAKPGKLPLVSVNQEKNSGTHILMITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRPNRPKSRESRDKQ-KKEMVYR----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08460-1", "uniprot_id": "KCMA1_MOUSE", "id": "Q08460-1", "name": "Calcium-activated potassium channel subunit alpha-1", "aln": "MANGGGGGGG----SSGGGGGGGGG-SGLRMSSNIHANNLSLDASSSSSSSSSSSSSSSSSSSSS-VHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINN-GSSQADGTLKPVDEKEEVVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSS-NPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIK-IEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRSRKRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRR----------------------------------------------------------LEDEQPPTLSPKKKQR-------NGGMRNSPNTSP---------KLMRHDPLLIPGNDQID------------------------------------------NMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELAKPGKLPLVSVNQEKNSGTHILMITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRPNRPKSRESRDKQNRKEMVYR----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12791-1", "uniprot_id": "KCMA1_HUMAN", "id": "Q12791-1", "name": "Calcium-activated potassium channel subunit alpha-1", "aln": "MANGGGGGGG----SSGGGGGGGGS--SLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINN-GSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSS-NPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIK-IEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESR----ILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRPKMSIYKRMRRACCFDCGRSERDCSCMSGRVRGNVDTLERAFPLSSVSVNDCSTSFRAFEDEQPSTLSPKKKQR-------NGGMRNSPNTSP---------KLMRHDPLLIPGNDQID------------------------------------------NMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIIT---------------------------ELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDKQKYVQEERL----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7ZC96-1", "uniprot_id": "KCMA1_DANRE", "id": "B7ZC96-1", "name": "Calcium-activated potassium channel subunit alpha-1a", "aln": "------------------------------MSNNINFN----------KNPDSSVSIS------------KMD-VIIPFTPDVPCDNNGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCNIKNKEAQKVNNPITIQADGTTKTGNEKEEAPASEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALGIYFIDSS-DPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQPLSYWECVYLLMVTMSTVGYGDVYARTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSYIK-IEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPTVCELCYVKLKLLLIAIEYKSEQRESS----ILINPGNHVKMQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKR----------------------------------------------------------IEDEHPSTLSPKKKQR-------NGGMRNSPNCSP---------KMMRHDPLLIPGNEQIE------------------------------------------SMDANVKRYDSTGMFHWCPSKEIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELKPIVFVGSLDYLRREWETLHNFPKVFILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGLVRQASVTTGSNIPIIT---------------------------ELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALLAEENALRGGYSTPQTLANRDRCRVAQLALYDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFEMVPTDLIFCLMQFDHNAGQSRASLSHSSHSSHSSSKKSSSVHSIPATNRQNRSSKAREARDKQNATRMNRMGPEKRWFTDEAENAYPRNIQIKPMSTHMANQVNQYKSTSSLIPPIREVEDEC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03720-1", "uniprot_id": "SLO_DROME", "id": "Q03720-1", "name": "Calcium-activated potassium channel slowpoke", "aln": "------------------------------MASGLIDTNFSSTLANGMSGCDQSTVES-----------LADDPTDSPFDAD---DCLKVRKYWCFLLSSIFTFLAGLLVVLLWRAFAF---VCCR-----KEPDLGPN------DPKQKEQKASRNKQEFEGTFMTEAKDWAGELISGQTTTGRILVVLVFILSIASLIIYFVDASSEEVERCQKWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGDPLD-FNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAMFASSIPEIIELVGSGNKYGGELKREHGKRHIVVCGHITYESVSHFLKDFLHEDREDVDVEVVFLHRKPPDLELEGLFKRHFTTVEFFQGTIMNPIDLQRVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPDMQSWTNDYLRGTGMEMYTETLSPTFIGIPFAQATELCFSKLKLLLLAIEIKGAEEGADS--KISINP-RGAKIQANTQGFFIAQSADEVKRAWFYCKACHEDIKDETLIKKCKCKN------------------LTVQPRSKFDDLDEHHPAPTFTPPELPKRVHVRGSVSGDITRDREDTNLLNRNVRRPNGTGNGTGGMHHMNNTAAAAAAAAAAGKQVNKVKPTVNVSRQVEGQVISPSQYNRPTSRSSGTGTQNQNGGVSLPAGIADDQSKDFDFEKTEMKYDSTGMFHWSPAKSLEDCILDRNQAAMTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELKHVVIVGSVDYIRREWKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKVPSNDDPTLADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSP------IVLQRRGSVYGANVPMIT---------------------------ELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGLRGGYSTVESLSNRDRCRVGQISLYDGPLAQFGECGKYGDLFVAALKSYGMLCIGLYRFRDTSSSCDASS-KRYVITNPPDDFSLLPTDQVFVLMQFDP-GLEYKPPAVRAPAGGRGTNTQGSGVGGGGSNKDDNS-----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:..: . .. ..* * * *. : * * :*.** **:.**:.**:::****:: : ***: **.: * * . * . ..: * :**..***** :**.** ***:****** ***.:* ***:*:* : :* **:: :::* ***:***:**::** :*****.***** **: *.**:**:** ***:**:*:*:**********: ..:***:**:****.**:*.:* *****.******:***:****** : *:* : *:** ***:*:************..*.*** *:***:* ******* :******:*. :****. . *::********* ****:*******:**:**:**:****. .*:****.******* ***:**:::** ** ***:..*****:****** *******:*********** .**:* *::******:*******:**:***.******* ********* *:***:****:***: . : ::* : **.*.. ***** **.:*:*:.*. . ***: *****::*** *. :. : * *** . *:* .* *****..*.*****:*******:*:.* . **** *:. .*.. ..* :: :* .***:: * :. * :.: : . *:: .:: . :*********...*.:*. ** *.:*:****.******:*.* *.*:******************** :*:***::*::***: *:*:**: :* *:***********:****** ****: . **.:* ***.********:* ***:****. .. * . .** :::: . . * *:*:** *****:***************************************:****:* *****:*:********* ::** .******* ::*:*******.*::* ***:*::*: * ***** ***:*.***:*:**:**: . :.. ********* :*.::*** :* ***** . : :.. ::. ..:.:..:.*.* . :. ", "identical_positions": 630, "similar_positions": 285, "identity": "45.45%" }, { "cls_id": "homologset.agr.RGD:620716", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91V61-1", "uniprot_id": "SFXN3_MOUSE", "id": "Q91V61-1", "name": "Sideroflexin-3", "aln": "-MGDLPLNINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGEQLEASRNIVQNYRAGVATPG-LTEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTVVFWQWVNQSFNAIVNYSNRSGDAPITVQQLGTAYVSATTGAVATALGLKSLT---KHLPP----LVGRFVPFAAVAAANCINIPLMRQRELQVGIPVTDEAGQRLGHSVTAAKQGIFQVVISRIGMAIPAMAIPPVIMNTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQRSSIHVTRLEPELRAQIQAQNPSIDVVYYNKGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHY2-1", "uniprot_id": "SFXN3_RAT", "id": "Q9JHY2-1", "name": "Sideroflexin-3", "aln": "-MGDLPLNINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGKQLEASRNIVQNYRAGVVTPG-LTEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTMVFWQWVNQSFNAIVNYSNRSGDAPITVQQLGTAYVSATTGAVATALGLKSLT---KHLPP----LVGRFVPFAAVAAANCINIPLMRQRELQVGIPVTDEAGQRLGHSVTAAKQGIFQVVVSRIGMAIPAMAIPPVIMNTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQRSSIHVTRLEPELRAQIQAQKPSIDVVYYNKGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BWM7-1", "uniprot_id": "SFXN3_HUMAN", "id": "Q9BWM7-1", "name": "Sideroflexin-3", "aln": "-MGELPLDINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGAQLEASRNIVQNYRAGVVTPG-ITEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTVVFWQWVNQSFNAIVNYSNRSGDTPITVRQLGTAYVSATTGAVATALGLKSLT---KHLPP----LVGRFVPFAAVAAANCINIPLMRQRELQVGIPVADEAGQRLGYSVTAAKQGIFQVVISRICMAIPAMAIPPLIMDTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQKSSIHISNLEPELRAQIHEQNPSVEVVYYNKGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VN13-1", "uniprot_id": "SFXN1_DROME", "id": "Q9VN13-1", "name": "Sideroflexin-1-3", "aln": "-MSPLPR-VNIDEPKYDQNSYLGRAKHFFLLTNPLNVLASASKLEEARQIVIKYRAGKDVPECKTIDDVWRAKYLYDSAFHPETGEKQIVIGRMAAQMPMNTIITGGMMAFYKSTPAVVFWQWFNQTFNAIVNYTNRSGTSPISQQQLVTSYCLATSGALVTALSLNHAV---KNMNP----LLGRLVPLVAVGAANCINIPCMRMQELRNGVTLFDEHSNEMGISKKAAVVGISTVILSRIAMAIPGMTLTPVLMNVLEKRGFLAKYPRSNAPIQTLFCGFVLIFATPLGCAFFKQRADIKVDSLESEVRDSIRKKRPELETVWFNKGL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12029-1", "uniprot_id": "FSF1_YEAST", "id": "Q12029-1", "name": "Sideroflexin FSF1", "aln": "MASSVPGPIDLPESRYDLSTYWGRIRHCAEISDPTMLLTTEKDLAHAREIISAYRHGELKET---TPEFWRAKKQLDSTVHPDTGKTVLLPFRMSSNVLSNLVVTVGMLTPGLGTAGTVFWQWANQSLNVAVNSANANKSHPMSTSQLLTNYAAAVTASCGVALGLNNLVPRLKNISPHSKLILGRLVPFAAVVSAGIVNVFLMRGNEIRKGISVFDSNGDEVGKSKKAAFMAVGETALSRVINATPTMVIPPLILVRLQRGVLKGKSLGVQTLANLGLISVTMFSALPFALGIFPQRQAIHLNKLEPELHGKKDKDGKPIEKVYFNRGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* ::: *.::* .:: ** :* :::* :* : .* :*:*: ** * :.**** **:.**:**:. :: **:::: * :* *:: *. ***** **::*. ** :* . *:: ** * * *.:.: .**.*: . *:: * ::**:**:.** :*. :*: ** .*:: *:.: *. .:.:* * .** .: . :**: * * *.:.*::: *:: : : : : : .. :. * *: .:* *: *:: **.*:: . . :: *::*:*:", "identical_positions": 87, "similar_positions": 115, "identity": "26.36%" }, { "cls_id": "homologset.agr.RGD:620717", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88996-1", "uniprot_id": "O88996_RAT", "id": "O88996-1", "name": "Bcl-2-like protein 2", "aln": "MATPASTPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQDWMVTYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70345-1", "uniprot_id": "B2CL2_MOUSE", "id": "P70345-1", "name": "Bcl-2-like protein 2", "aln": "MATPASTPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQDWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92843-1", "uniprot_id": "B2CL2_HUMAN", "id": "Q92843-1", "name": "Bcl-2-like protein 2", "aln": "MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:********************************************************************************************************************:***:****:************************************************************", "identical_positions": 189, "similar_positions": 4, "identity": "97.93%" }, { "cls_id": "homologset.agr.RGD:620718", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT59-1", "uniprot_id": "E9PT59_RAT", "id": "E9PT59-1", "name": "", "aln": "MEAEEPEHGACTPVPDIEELGAIPEGIMRSSQIPALDPEAQEGQDPSYKWTDGHRSLMDQSKVLRDVSDHTPNSVAIFFKKDSSAMATSQEILLAEARDTADQQEAVTQSLQDRLSTTVAAPELLGCAVQEEWLDIP---SKLDS-RVEAELQPELMSLTLAVSKEKEEEESSPDTSTP-GFWPPSKIHPGETDQTEGSGMELLRQGKQLQLEATQENRGQQGLLQPQEAQGLEEQEGQEVEIQEEGTLREDICFGGLLGEQKEVEEDFNDN-KEEQKQEQIQSYMLLGGQWESEGLSGELEGLNYNERSQEERERRVCGQRDSKE-EGQDQELREVEERRVGTQCAENQMLEEISENVRRRQEDHDQAGQAMHVGDQKEVVDSGDREQGTWDSGGQAAEERSRTGEDNKPCLPMTSIAPGVLSPGTLFPAIPSSVDDMSQIQREPVPEELTTQAPTPAPEPTEWSHQHISPPASFATEEALDN-RTHDSQQEEFKLRKGTISNQGTENVSASISVAPSGTPDLPPFTPPNVFPTTATFSLVSSSVILPEKETPAASISADISPHYGPCETPPLPAKSTRDPCAT----SDTANPHSPLTSYTGVTQHLRSNSFPGSHRTEQTPDSMGMSLSFSHLELPQRPP--KTAIYGSLIPRRNRRS-RDGVVFSESSAALFALKQDSEEFTSNPESSSNPHGSQPWGSPQNSAFAIGSPVNVSSPPTVSMDM--IHEALPPPPPEKRHSYSHIVERDGLFHEVAATLKRHSHPPPLTLSSGLHRSPKGSFSLVPDSVVARQHRPLPSTPEGSHHTQTSIPSRLRYNKPLPPTPDMPEPCHSSISSSNISRIYRPLPPVPITDPSSEPPPLPPKSRERSRSVQVGVMHSMGQANPRTTGQDWTVST-LSVGRTSWPPATGRSTESLPPTSRCNSEVSPGLAFSNMTNLLSPSSPTTPWSPELQIPTSKDESGLTEESAPPVRGSFRRPALQEEFNNTRRSALGSRKKSEKPIHYQLEKASSWPHRRDTARTS-ESSSEQVVLGQAPNKQKGWNRQGLRRPSILPESSSDLRNPAAGRLPGSSDSVVFREKKPKEGMGGFSRRCSKLINSSQLLYQEYSDVVLNKEIQSQQRLDSLAEPPGISSPRYRRKALVSSDSYLQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEAKFELIVSEASYLRSLNIAVDHFQHSTQLRATLSNQDHQWLFSRLQDVRDVSTTFLSDLEENFENNIFSFQVCDVVLDHAPDFHRVYLPYVTNQTYQERTFQSLMNSNSSFREVLEKLESDPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSEEAEATKAHHALEKLIRDCNSNVQRMRRTEELIYLSQKIEFECKIFPLISQSRWLVKSGELTALEFSVSPGLKRKLTTRPVHLHLFNDCLLLSRPREGSRFLVFDHAPFSSIRGEKCEMKLHGAHKNLFRLFLLHNAQGTQAEFLFRTETQSEKLRWISALAMPREELDLLECYDSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGEQGWFPLQQVEFISNPEVRVQNLKEAHRVKTAKLQLVEQQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q7D5-1", "uniprot_id": "ARHG5_MOUSE", "id": "E9Q7D5-1", "name": "Rho guanine nucleotide exchange factor 5", "aln": "MEAEEPEYGVSTEVPDIEELKTIPEGIMRSSQIPALDPEAQEDRDPSYKWTDGHRPVMNQSKVLRDMGDHTPNSMAIFFKKESSDMETSQEILLAEACNTPDQQEAVIQSLKDRLSRTIAAPELLACAVQEEWLDIP---SKLDN-RVGAELQSELMSLTLAVSKEKEEEETSPDTSIPRGSWPPCKTHPGETEQTQGSGSELLRQGKQLQLEATQENQGQEGFLQSQEAQGLEEQEGQEVEIQEEGTLNEGICFGGLLGEQEEVEEGFNGN-EEEQKQGQIQSYMLLGGQWENEGLSGELEGLNYSERGQENRERRVWVLRDSEE-EGQDQESREVEERRVATQYTENQRLVEKSEIVKRKQRDHDQTGKVMPVRDQKEVVDSGDRVQGNGDSGGQTAVEGSRPGEDSKPSLPVASVDPEVLSPGTLFPGISSSVADIPQIQKEPVCEELSPQAP--ALEPTEWSHQPISPPASFAPEESLDN-RTHNSQQEEFRLRKG------IEVVSASTSVAPSGTRDSPPFSPPNVFSSTATLSPVSSSVILP-EETPTASASADTPHHCGPCETPPLPAKSSRYPCAT----SDTANPHSPLSSYTGVTQHLRSNSFPGSHRTEQTPDSLGMSLSFSHLELPQRPP--KPAIYGSLTPRRNRRS-RDGIVFSDSSTALFALKQDSEEFTSNPERPSSPHGSPTWGSPQNSAFAIGSPANVSSPPTVSMDMT-IREALLPIPPEKRHSYSHIVERDGLLHEVASTLKRHSHPPPLTLSSGLHRSSKGSFSLVPDSTVARQHRPLPSTPESPNHTQTSIPSRLRYNKPLPPTPDMPEFYHPSISSSYISRMYRPLPPVPIIDPSSEPPPLPPKSRGRSKSIQGGVIHSGGQAKPRPNNQDWTAST-LSVGRTSWPPATGRSTESLPLTSRCNNEVSPGLAFSNMTNLLSPSSPTTPWIPDLQRPTTKDESGLTEESEPPVRGSFRRSAPQEEFNNTRRSALGSRKNSEKPLHHQLEKASSWPHRRDPARTS-ESSSEQVVLGQVPNKQKGWNRQGLRRPSILPESSSDLRNPAAGRLPGSSDSVVFREKKPKEGMGGFSRRCSKLISS-QLLYQEYSDVVLNKEIQSQQRLDSLAEPHGLSSPRHRRKALVSSDSYLQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEAKFELIVSEASYLRSLNIAVDHFQHSAQLRGTLSNQDHQWLFSRLQDVRDVSTTFLSDLEENFENNIFSFQVCDVVLNHAADFHRVYLPYVTNQTYQERTFQSLMNSNSSFREVLEKLESDPICQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSEEAEATKAHHALEKLIRDCNSNVQRMRRTEELIYLSQKIEFECKIFPLISQSRWLVKSGELTALEFSVSPGLRRKLTTRPVHLHLFNDCLLLSRPREGSRFLVFDHAPFSSIRGEKCEMKLHGPHKNLFRLFLLHNAQGTQVEFLFRTETQSEKLRWISALAMPREELDLLECYDSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGEQGWFPVQQVEFISNPEVRAQNLKEAHRVKTAKLQLVEQQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12774-1", "uniprot_id": "ARHG5_HUMAN", "id": "Q12774-1", "name": "Rho guanine nucleotide exchange factor 5", "aln": "MEAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQQSELRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLAPPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGSESGTIRQGEELPPEELQES---QGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQD-VMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQ-EAKEPESWDGGRLGAVG-RARSREEENEHHGPSMP-ALIAPEDSPHCDLFPGASYLMTQIPGTQTESRAEELSPAALSPSLEPIRCSHQPISLLGSFLTEESPDKEIDQNSQQEESRLRKGTVSSQGTEVVFASASVTPPRTPDSAPPSPAEAYPITPASVSARPPVAFPRRETSCAARAPETASAPLSMDDPSPCGTSEMCPAALYGFPSTGTSPPRPPANSTGTVQHLRSDSFPGSHRTEQTPDLVGMLLSYSHSELPQRPP--KPAIYSSVTPRRDRRSGRDYSTVSASPTALSTLKQDSQESISNLERPSSPPSIQPWVSPHNPAFATESPAYGSSPSFVSMEDVRIHEPLPPPPPQRRDTHPSVVETDGHARVVVPTLKQHSHPPPLALGSGLHAPHKGPLPQASDPAVARQHRPLPSTPDSSHHAQATP--RWRYNKPLPPTPDLPQPHLPPISAPGSSRIYRPLPPLPIIDPPTEPPPLPPKSRGRSRSTRGGHMNSGGHAKTRPACQDWTVPLPASAGRTSWPPATARSTESFTSTSRSKSEVSPGMAFSNMTNFLCPSSPTTPWTPELQGPTSKDEAGVSEHPEAPAREPLRRTTPQQGASGPGRSPVGQARQPEKPSHLHLEKASSWPHRRDSGRPPGDSSGQAVAPSEGANKHKGWSRQGLRRPSILPEGSSDSRGPAVEKHPGPSDTVVFREKKPKEVMGGFSRRCSKLINSSQLLYQEYSDVVLNKEIQSQQRLESLSETPGPSSPRQPRKALVSSESYLQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEVKFELIVSEASYLRSLNIAVDHFQLSTSLRATLSNQEHQWLFSRLQDVRDVSATFLSDLEENFENNIFSFQVCDVVLNHAPDFRRVYLPYVTNQTYQERTFQSLMNSNSNFREVLEKLESDPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSEEAEATKAHHALEQLIRDCNNNVQSMRRTEELIYLSQKIEFECKIFPLISQSRWLVKSGELTALEFSASPGLRRKLNTRPVHLHLFNDCLLLSRPREGSRFLVFDHAPFSSIRGEKCEMKLHGPHKNLFRLFLRQNTQGAQAEFLFRTETQSEKLRWISALAMPREELDLLECYNSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGERGWFPVQQVEFISNPEVRAQNLKEAHRVKTAKLQLVEQQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RFG0-1", "uniprot_id": "A0A8M1RFG0_DANRE", "id": "A0A8M1RFG0-1", "name": "", "aln": "MDRER------------AMMQDSCDGTRERDRLPAIRRREMDWRE-RERWRDGDQYANGKS------------SLFEHTVHGERDKESKKGDTFPRMTKANRERDRRIPLSENERQRRLGRPKDTTYEDEKEREKRR--YRDMDTRRRMKEHSDKLREQEFELGIRGRRREGHTGTNDPTGMREKETDRERDRYRQRDREVRYYPRPIERETESFSDKE-----WRTERQNGAERSRKRDTKSEGD--------SDGDRGKEMNREAVTKPGHKLYKSEGDSKADQRVDRVREKDRRRDQEVWRYKEMVRPREKDYRETGYYDKNGMRKDKRPDRDAYSNTPERGRYRNAELE-KDGYSEREIEDRERWRRQNREPYRDKMEKSGQRTGGKISGVEIEKEHNRSVGENLEDRNRKNTSESEKEKLKGRTDGEQEVRIAPREEEGRQIVVEETVTKKFTGRIMNRWLEPRREKNPSLLEEDYRDR--ERARERYNQRFKESTKYEEDPARNNESKRTSAKDKYRAGEFMGDIDVESNEKLDKQEDMVNDKEAVEPEWRAKREIGGNNMEVNEREEERSIDRHDYSG----------IEEGSEGESRAEKDRIISADDGFVTVSSGGDIEDCMDFRNGEVPTDISGCSEATQGEEREPLRVFCVIGQTPIESQTKQNPYIDTASEEATDQHSDQNIDIQGVMFIEDANEAFEKFEHKESDIEGAMDDLALSANEEKVEQTGDNDQGTDDITSLKGQMIPSKEGAEEEPAEPSVTLDPCNDDGPETIVAPSEDALHRREMEATGNTEEHFDSDDTWSTCEERKRCSTAPHLTWAKNVVKEILGPNSEDTEHMRGSVTHIDIQINTQTETDREINISR-EHEELIQGEEKEQGEIEKESDEETILLDPSCIEQTVSSKREADRTVEGHVSKRKDSIENVILGSSSFRELGNEARIRRRGIR----KTTEGTKEEEEDEEEGGVGRDRRTRVFNNSDAE--------------EDELCLTWSE------------GDLRKLGRTKKRSSKYFNSQLYQEYSEVVQNREILLTNYDTTSLSGDNITIRSSSP---LNHSPKLSHRPLPALPQVHLHPHSLSLNNSLKSLN-----LPQQSINRPPSPRLSIS-----------ASSPTLWQDLPGVRNSPEIVELTEDERRLQEVRFEVVTSEASYCRSLDIVVENFVLSKQLNAILSSQDKNWLFSRLNDVRAISHSFMSHLEENVERDMLHFTVCDIIIKYCPRFRNVYVPYLTNQSYQDKTYQRLMDESQEFRRVVEKLERNPVCQRLPLRSFLILPFQRITRLKLLVQNIVKRTAPKTKDEVQAIKAMKLLEKMILDSNESISQMKNIESLVTLNAKVDFECRTLPLISQSRRLVREGPVTELRDFS---LKDREEERSVYMHLFNDYLLLSIRKEGGRFTVIDHAPVSELRAENCRFKLHSLQKNLFRLHMP------QKALLLRTDTQADNLRWISALSRPYPEIDFGAVQETPQMQCIRAYVAQQPDELSLEKADVLVVHQQSSDGWVEGTRLSDRQRGWAPELHLETITSDKARKRNLLDTMKIATAAM-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *. : :. . .::.*: . : .: :* : .: :. :: . . . ..: ... .: . : .. :. *: :.* . .:.. . * * . : . ...* .... : : : .. : : * .:. :.:. : *.. ::. . : .* *:: * . : :.: : : :. * .: .: : : . : . .: : .. .. : . . .*: : : : .. . * .. .*. . . : . * : . . . . *: *: *. : :: : ::::. * .:. . . * . : : . : :. . .:: * * ... * .: . : :.: : *:* . . * .. . . .. .. :. *:* .: . . : . * ** . . :. .* . :. . :.. .* :... *.::*.. . : .. *. *: .. .* : . :: . * . . .* .: * .. . : .:. * :. . . :. *: : ::. : : . :. . . . . . :: *.:: .: : * .: . :.: .. : :: * * .*. . . * . ... . . * . :*.. .: .. :: . : .. * : . : . . ..*.:.:*...* :. .: . : : : :: . .: **:.::* : . . * * :: *** :***::* ****. ::.:*.::::***.:**::.***** ***:*.*::* * .*.. **.*:::******:*** :* :*:*.****.*.::: * ***:::.:.. *:.**:**:***:**::*:* **:....**.*:**** :*:****.*:****************:***:*** * :.:*.:* ** : **::* *.*..:. *:. *.*: *. *::***: :******* **:.* :* *. *: : *.*::***** **** :**.** *:****.*.:*.*:*.:***. :******.: * :*:**:**:::*******: * *:*: ::**:**:*** .:: ***:******::* *******:**.**** ::** * ::* *:. :.* :** :: :: ** : ", "identical_positions": 287, "similar_positions": 487, "identity": "17.85%" }, { "cls_id": "homologset.agr.RGD:620719", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43307-1", "uniprot_id": "ARHG9_HUMAN", "id": "O43307-1", "name": "Rho guanine nucleotide exchange factor 9", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLLITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEE------------GWFPASFVRLWVNQEDE--------------VEEGPSDVQNG-------------------------------HLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHS------------------------------DYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVVDIEDGRDDDFNVSMKNAFKLHNKETEEIHLFFAKKLEEKIRWLRAFREER----KMVQEDEKIGFEISENQK-------------------------------------RQAAMTVRKVPKQKGVNSARSVPPSYPPPQDPLNHGQYLVPDGIAQSQ----------------VFEFTEPKRSQSPFWQNFSRLTPFKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UTH8-1", "uniprot_id": "ARHG9_MOUSE", "id": "Q3UTH8-1", "name": "Rho guanine nucleotide exchange factor 9", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYDLITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQIDDEE------------GWFPASFVRLWVNQEDG--------------VEEGPSDVQNG-------------------------------HLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHS------------------------------DYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGEDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVIDIEDGRDDDFNVSMKNAFKLHNKETEEVHLFFAKKLEEKIRWLRAFREER----KMVQEDEKIGFEISENQK-------------------------------------RQAAMTVRKASKQKGVNSARSVPPSYPPPQDPLNQGQYLVPDGIAQSQ----------------VFEFTEPKRSQSPFWQNFSRLTPFKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QX73-1", "uniprot_id": "ARHG9_RAT", "id": "Q9QX73-1", "name": "Rho guanine nucleotide exchange factor 9", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQWIRGGSGMLITGDSIVSAEAVWDHVTMANRGVAFKAGDVIKVLDASNKDWWWGQIDDEE------------GWFPASFVRLWVNQEDG--------------VEEGPSDVQNG-------------------------------HLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFSDEQLKVIFGNIEDIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHS------------------------------DYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGDDILDRSSELIYTGEMAWIYQPYGRNQQRVFFLFDHQMVLCKKDLIRRDILYYKGRIDMDKYEVIDIEDGRDDDFNVSMKNAFKLHNKETEEVHLFFAKKLEEKIRWLRAFREER----KMVQEDEKIGFEISENQK-------------------------------------RQAAMTVRKASKQKGR-------------------------VGEEENQ----------------SLELKRACEVLQRLWS------PGKKS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W0S2-1", "uniprot_id": "Q9W0S2_DROME", "id": "Q9W0S2-1", "name": "", "aln": "MATETFLDLNYERGKVSKRSLRPKLLKLTDVTIPHRSRKKNKVKTKDRSATSVRDRIYDDPAYTEDISHLANPMRRSSISGKSFLEHKTRSDTGGQASSSSLLAKNQLPQELHQYVSGKQAKIKQHHTATIASGSTAISINYECDSSSTDNEVQEPIQTKGGMNRRVRSLERNLAATGSERAEKKGTQKRTSKQKRNLSLDNNRHQPAGHPKREAVAVAKVGHDADTRARKERNRKPYGEMGPDGGVPTEVSELDDGYSARGSAQSSACTLPAESAADAAKVAIGKRFLRGEIGIKSFNYYLLKEGLKSSKKLVDQQRTPAGSGSVESPLKAEKRHCRSEENIYEEIFFKDTANAVSSSATGVATGMAMPVALTMCDQETHSLEKGAQPHGIGATNPAFADCEFCMEQCSKENCEYCLAHVEQVASKKLKAGQTQEEQYLNQGHRKNHTMDSRPSAPVVEVPTAHILEFQSYNPNNPGVYKIETTPVAITGDYNPILQFQQSSATTSTSATTTPSEPQIYGGYYLPHANQRPYHSPTVNSQLPNHYAVGGSLLLAQVTGATQGSATPPRRPQQHFIVGYQNGGGMSAGAASLQRFNTKSSSSSDSLPYHKYNTMARLEANVLAAPATGDLYYAVSGTQPLHPLMYAANRPIGGSQILVDPYDPQMYKSDSKASILSEFSLRSSDNSQRYARHPHRRHGGRVSDSSLFSVYSNSGQRRYFGSSEGRFGYDCRRCSLDGVIGMSTATGGSMMAPDKCSYSDNCRFECRNCDCSSNYFSSDFDDVYGSIARGGSSGIPRKTAAGTLPSSAQDDQVERLEAPPASMEQQQYADLKQNKYAQDFFKHVNDVKRSIYQSEMKRNNSLESSRSGPRAGGSTKSNVKASPKRAASQETRLVTTLPLSRSRLSAGVKPTPAPRTSLQTPTPLPETTVAKDPTPSKRKSQPTVRREYPSLDRLVASTTGTIPKKNSRNITAASLQSPKLTQKTRSEAPEKKVAPEDQLPLPPSGKRHHRTGASKTNTNAPCSSLRRKDIPAPPPPSPATYSDLQELKANMEGFRDDTKSRSLEYDTNDLTADDNSNKTQKKSLSGPPNPMTEAPIGATDAGAVETDDNDVFYDARSEDSGGGILPSNTSDISKMSPSHMATFTRAATNENRKGAFDNEKEHSAEDDDSPSPAAPAPEGREQASSITGRPKGNGNSKITTTPSCELGSSAEAESKLDSAALCRPRPRPRQASPHLPPECTDTGGAGDEQASKTKHEKKTPADAPRQHVGPTCSEGQRTAALATNVACALSTTTNAGNTSASNSVLELELSCKTGNTDSETPAVAHSDPTSDVPACGTAENPTHLRALTRQDYACIDSSEAQSDDSHLTRDSITRESQNDELSSSTLEKLDVSTLPLPALPKRRRTRSRTSPSKHRQQQQQQQQQQQQRHEVIEDANAVDASTAAAGQQHPKPRQGAASPESQKPEISGAKNNAAGEQQKQPQSQQQQTHLSAFQQYVAKRRESLEASNRCFNEKLEARRMHYHMGGSAANGNATASHLTAGSNGVPTYLFGENFYGVPATGRKSISPTTKKEEIFLNKSGWVQVNTTRGVNKDDNGGGYRSLSYAQQNGGGRVAAMLTDPGRRSDLARKSFILQHQQQHQSNISMTEPKFVGSKVEELIQRNEARLSGCSIRYPSLRPGHRIIDPQLANILNERPGFLPVKGPTDLDSPLTPILSPPPAFQDNSRSARRQERRNPGRQQGPLPLPVPFRSEPQMDPQNPINGSAKGMVFSRSFEYDTRRHTPTDNYVETFSRSFDGNLSDRLLNLAVLAGQRERSPNFSTLTGNSPNYLTKRESGGGSSGSLRSRDSSPKYLHPQATTAYLNAAVKEAPPVYSVPTGSQAKYSPRSRFERTTERSKTHALGRSRKSQFSRVGSAGPLIAHPNTANVGVSRFRSFDTSKSQRLNSCDSGARSDLSNDELDNEDGGLNDFLSAGSHKFPKIGTSSVSVSPFKMQRQRSLTPDRNDSHSSTSSLRKQRSNTPESRSLTPEERRKKGSQLSLGGARQSSSSRSNTFEGRQRHDDKTPPNISRSSSSSSYSGGESHEPLNGTGSTTVTPSAGSGSTSHRRALTAKQAEQEHRIRRSRSLQLTERSPNRAHKSIVNVGALVPQQRSVGVPYQQSRVPGGGVFPPTIRTSPAGAKIHVNSPAPPNSSVRVRHNETDKARSFDFDYNNFSRGGGAKGSSRTAHTSGSGGDSGSNQNLRVERESRSFDDEICEAVLNNNNGSNGSVSGLRFLQPATDSGQVSMASTSSSRLRKSNSPVSASGMEASRSPQSSGSSTNNLHQQARQSGSPQSYGTRLCDHELTYEMLRKSPIMNFRRGDSGDYELPVMLRNRETINSGGNSELNFMSNETRIYEHPTTVLKSQRSLRQSPGSRDDLNLEVAVGVGGDYIYRQPANQPRSSSVKAEFLTTATTKSCTKTLDTCDYWPRCAACQHKSVSGELKKGPSASGKPLTVLDNVQPHVTSVIVNEDNAVPGPQLRSLEKSNPSWTFLCSGIASICQPVQQTETDHSTAQEAAEEDIVIRKVKPNKSRRTGRSRSLPSVMLRRLYLAGMPKPGSNEMGTTSDCAASLSQQIKAVSSPTLSEPCLEEQPQKGTESTDVANTGSSAGSGGLGVLQKFKRTLNNFNNKNQLHISPLSPAAVGNNAPKTKTSPTTTTASIAPMITTTTASDPGSEAGDTSSGKYRFGPLIWRSSKERRKTKYNRRDKCNSGDSGIQIELEQDEQYSRATMAVSRQDEPRAFALTNGSCGVALSKMRAIRRTNSAKASSILGPFIVKTKIAKHLNIGESDKAERKAPESLPTRSLSQPNGLESYGMGRPDLEDSDSDSVASNEEAISFYPTTYAEVLYNFTAGGPQELGLERGMLIEILRKEVGPWWFGRIKKEETNLVEDILGPELGWFPKEFVRIIHCPETDNFFIAHRAAADEAAAEEATARAEEGSVPVPVAAFAEDTDVTVTTDQSNVTLIVIESPPTPSAPSVDFVAQPDHSTIIRRSAVRELLDTEVNYVKLLAAICDGYLPAMSKRIDIFSPNSIRLIFSNITAIYKFQRKFLEALRRGIEQN-----QVAKVFLKMHKGFLCYSTYCNAYPRALIELETYDRVKDARTILENCRESQNLAELPLSAHLLAPVQRICRYPLHLNEIIKSALEKGAKEGNDTDGAKSAGKTTDYEQLDVTELDIPDSQDTVNLALEAMRGITEAVNEGKR---HSETIARHQASFQNFKGPPLHLHSARFFLQVDATRQKQ-NLWNSSYTLFLFDNQLVYCKRDIIKRSHFIYKGRIFLDRCRVVNVRDGK--MFGHTIKNSLRIYSESRDKWYDFSFRSANRKHRFLSTLALERQFGGKALYVSEMTGFEYNYEERPGDYSDQSDYDAQDFELATGVTSGESSLPESPAKSTSRLCETLPKKSQSRDGISSAENSQIVTTTSTGSLGRRHFGNWFRKPKSANCTPSQSPTHKPSFDADATLTEARVAAMELAEAAAALVPTDSSSA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . . **.:::..: . : :.:: * :*::* . **:*:*..** **** .***: * .**..: .::* *.: .: : :: :* ..:.*::.** :*:* * **:*** ** *:** :.:::**.** **:** *:. *.: ::: ::. **: :.** ** *** : * :**.. : . : ::* ** *:: ::.:...**:***:**:***:* *::* : :. : . * ** .**.:*: :** ** : :.**: ***. :::* : :*:.:: : : * *.. .:****:*:* **:*:*:*. : ***** :*: .*:::.**: *. ::**:::::.:. :: : * :. :.* *:* :: ** * : .* *** . ::: * . :* .:.* :. :... : . * .. ", "identical_positions": 137, "similar_positions": 183, "identity": "3.88%" }, { "cls_id": "homologset.agr.RGD:62072", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62666-1", "uniprot_id": "VACHT_RAT", "id": "Q62666-1", "name": "Vesicular acetylcholine transporter", "aln": "MEPTAPTGQARAAATKLSEA------VGAALQEPQRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYIAHMRGGSEGPTLVSEVWEPTLPPPTLANASAYLANTSASPTAAGSARSILRPRYPTESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVMFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLP-VGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMVWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGVSSCVVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRSERDVLLDEPPQGLYDAVRLRE-----------------VQGKDGGEPCSPPGPFDGCEDDYN-YYSRS--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35304-1", "uniprot_id": "VACHT_MOUSE", "id": "O35304-1", "name": "Vesicular acetylcholine transporter", "aln": "MEPTAPTGQARAAATKLSEA------VGAALQEPQRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYIAHMRGGSESPTLISEVWEPTLPPPTLANASAYLANTSASPTAAGSARSILRPRYPTESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVMFAFAEDYATFFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLP-VGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMVWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGVSSCVVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRSERDVLLDEPPQGLYDAVRLRE-----------------VQGKDGGEPCSPPGPFDGCEDDYN-YYSRS--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16572-1", "uniprot_id": "VACHT_HUMAN", "id": "Q16572-1", "name": "Vesicular acetylcholine transporter", "aln": "MESAEPAGQARAAATKLSEA------VGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYIAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLP-VGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRSERDVLLDEPPQGLYDAVRLRERP---------------VSGQDG-EPRSPPGPFDACEDDYNYYYTRS--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08C75-1", "uniprot_id": "VACHA_DANRE", "id": "Q08C75-1", "name": "Probable vesicular acetylcholine transporter-A", "aln": "MATEESGGLAQTAAVKLSEMGERTKQLGNAIQDPERQRRIILVIVCVALLLDNMLYMVIVPIVPDYLAHLESESE-------------QAHVKGNSSINIT--------------------QNENFDLQIGVLFASKAILQLLVNPLTGTFIDRVGYDIPLLIGLSIMFVSTCIFAFAENYATLFMARSLQGLGSAFADTSGIAMIADKYAEESERSRALGIALAFISFGSLAAPPFGGVLYEFAGKRFPFIALACVCLADGILCLTVLKPFS--SRTRENMP-VGTPIYKLMIDPYIAVVAGALTTCNIPLAFLEPTIANWMEETMNASQWQIGITWLPAFFPHILGVYLTVKLAAKYPHLQWFYGALGMVIIGASSCIVPACKNFEQLIIPLCGVCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYCVAYALGPIVAGKIVHDLGFVQLNLGMGLANVLYAPALLLLRNVSLMKPSHSERNMLLEEGATGLYDTIRMEERQRKK----------HGYSSSGNCVPIDENGTFAGQSKSFSEEETSEPEYI----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P59845-1", "uniprot_id": "VACHB_DANRE", "id": "P59845-1", "name": "Probable vesicular acetylcholine transporter-B", "aln": "MQSTGAPGLAQSAVLQLSAMGERSRELGGALREPERKRRLLLVVVCVALLLDNMLYMVIVPIIPDYLADLRGE-------------------RGNS--------------------------SADLDIQIGVLFASKALLQLLVNPLSGTFIDRVGYDLPLLIGLLVMFLSTCIFAFAENYGTLFAARSLQGLGSAFADTSGIAMIADKFTEEAERSRALGIALAFISFGSLVAPPFGGILYEFAGKRVPFIVLACVCLADGVLLLTVVKPFS--DRTRENMP-VGTPIHRLMVDPYIAVVAGALTVCNIPLAFLEPTIANWMESTMDASKWQMGLVWLPAFLPHVLGVYITVRLAARYPERQWFYGALGMVIIGASSCTVPACKTFGELVFPLCGICFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYAMGPVVAGQIVHNLGFVQLNLGMGLVNVLYAPALLLLRPVCQIKPSFSERNVLLEEGPSGLYDSIRLEERALRR----------KGLSAGAG----TEHG-LRGRSE---EEEESGPESA----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O17444-1", "uniprot_id": "VACHT_DROME", "id": "O17444-1", "name": "Vesicular acetylcholine transporter", "aln": "MASFQIP-VINLEVREVKDI------VWEKIQEPVNQRRLILVIVSIALLLDNMLYMVIVPIIPDYLREIGSFDDGPT----------PPPLRDNITGKIIP----------------VHHDHHGQDSATGILFASKAIVQLMVNPFSGGLIDKIGYDLPMMIGLTIMFFSTAVFACGSSYSVLFFARSLQGAGSAFADTAGLAMIADRFTEENERSQALGIALAFISFGCLVAPPFGGALYQFAGKEVPFLILALVCLLDGLMLLLVMKPVKEAMKQSKDVQDQVIPIWRLLMDPYIAVCAGALTMSNVALAFLEPTISLWMEDNMTTDNWKIGMVWLPAFFPHVLGVVITVKMARKYPQHQWLMAAGGLALEGFSCFIIPFCSGYKMLMLPICVICFGIALIDTALLPTLGYLVDVRYVSVYGSIYAIADISYSIAYAVGPIIAGGVVEAIGFTALNFLIAFSNLAYVPVLRKLRNIYDFKPFENEANILMQDPPNKEYQTYVMHDQKPVEGGVKNHLEYGQQYQQEQETNLDDQQYEYQQQQQGYQQGYQQDQGYQPGYQEQGGSYAPQGQPRVANPFQQQQQQQQQQQQQVQSRGPAAPANPFRQGF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . . ::. : :::* .:**::**:*.:***************:***: .: . * . * *:******::**:***::* :**::.**:*::*** :** ** :** ...*..:* ****** *******:*:*****::.** ***:***:********.*.****** **:****..**: ** *.* *.:: * * **.. : :: ** :*::****** ***** .*:.********: **: .* :.:*::*:.*****.**:*** :**::* :**. **: .* *:.: * *. :* * : *:..:* :******:********.:*****:******:********.:***:**::** :*. :** *.: :.: *: *.*.* ** : :. .* ::*::: . *:: :.: . .. ", "identical_positions": 221, "similar_positions": 141, "identity": "36.17%" }, { "cls_id": "homologset.agr.RGD:620720", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80ZM7-1", "uniprot_id": "T2AG_MOUSE", "id": "Q80ZM7-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MA----YQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINSALAQRVRNRVNFR-GSLNTYRFCDNVWTFVLN------DVEFREV--------TELIKVDKVKIVACDGKNTGSNTTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08950-1", "uniprot_id": "T2AG_RAT", "id": "O08950-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MA----YQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINSALAQRVRNRVNFR-GSLNTYRFCDNVWTFVLN------DVEFREV--------TELIKVDKVKIVACDGKNTGSNTTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52657-1", "uniprot_id": "T2AG_HUMAN", "id": "P52657-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MA----YQLYRNTTLGNSLQESLDELIQSQQITPQLALQVLLQFDKAINAALAQRVRNRVNFR-GSLNTYRFCDNVWTFVLN------DVEFREV--------TELIKVDKVKIVACDGKNTGSNTTE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P52656-1", "uniprot_id": "T2AG_DROME", "id": "P52656-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MS----YQLYRNTTLGNTLQESLDELIQYGQITPGLAFKVLLQFDKSINNALNQRVKARVTFKAGKLNTYRFCDNVWTLMLN------DVEFREV--------HEIVKVDKVKIVACDGK-SGEF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5B9-1", "uniprot_id": "T2AH_DROME", "id": "Q9W5B9-1", "name": "Transcription initiation factor IIA subunit 2-2", "aln": "MN----YQHYRATTLGRTLQDTLDEMMERGDITKKIANLVLLRYDKSISTALKDHGTSNMSFTAERLETFRCCDNVWTLILK------DAEFRED--------QHSLKVDVVKIVACLGTDNGNE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32774-1", "uniprot_id": "T2AG_YEAST", "id": "P32774-1", "name": "Transcription initiation factor IIA subunit 2", "aln": "MAVPGYYELYRRSTIGNSLVDALDTLISDGRIEASLAMRVLETFDKVVAETLKDNTQSKLTVK-GNLDTYGFCDDVWTFIVKNCQVTVEDSHRDASQNGSGDSQSVISVDKLRIVACNSKKSE-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: ** :*:*.:* ::** ::. * :* ** :** : :* :. .:.. *:*: **:***:::: : ..*: :.** ::**** .. . ", "identical_positions": 30, "similar_positions": 38, "identity": "23.44%" }, { "cls_id": "homologset.agr.RGD:620721", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CY64-1", "uniprot_id": "BIEA_MOUSE", "id": "Q9CY64-1", "name": "Biliverdin reductase A", "aln": "MSTEPKRKFGVVVVGVGRAGSVRIRDLKDPH-SSAFLNLIGYVSRRELGSLDNVRQISLEDALRSQEVDVAYICTESSSHEDYIRQFLQAGKHVLVEYPMALSFAAAQELWELAAQKGRVLHEEHIELLMEEFEFLKREVAGKELLKGSLRFTASPLEEEKFGFPAFSGISRLTWLVSLFGELSLISATMENRKEDQYMKMTVQLETQNKSPLSWIEEKGPGLKRNRHISIHFKSGSLEEVPNVGVNKNIFLKDQDIFIQKLLGQVSAEDLAAEKKRILHCLELASDIQRLCHRKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46844-1", "uniprot_id": "BIEA_RAT", "id": "P46844-1", "name": "Biliverdin reductase A", "aln": "MDAEPKRKFGVVVVGVGRAGSVRLRDLKDPR-SAAFLNLIGFVSRRELGSLDEVRQISLEDALRSQEIDVAYICSESSSHEDYIRQFLQAGKHVLVEYPMTLSFAAAQELWELAAQKGRVLHEEHVELLMEEFEFLRREVLGKELLKGSLRFTASPLEEERFGFPAFSGISRLTWLVSLFGELSLISATLEERKEDQYMKMTVQLETQNKGLLSWIEEKGPGLKRNRYVNFQFTSGSLEEVPSVGVNKNIFLKDQDIFVQKLLDQVSAEDLAAEKKRIMHCLGLASDIQKLCHQKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53004-1", "uniprot_id": "BIEA_HUMAN", "id": "P53004-1", "name": "Biliverdin reductase A", "aln": "MNAEPERKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHVELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLVSATLEERKEDQYMKMTVCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGVNKNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:**:*****************:***::*: *:*******:********:* *:******** ***::*****:*************:***********:**:********** ***:******:******* **::** **:****** ***.*****:************************:***:*:*********** ***::*. ***************::.::*.*****:**.************:**:****.*.* ::********:*** **.:**: * ::", "identical_positions": 232, "similar_positions": 50, "identity": "78.38%" }, { "cls_id": "homologset.agr.RGD:620722", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P22893-1", "uniprot_id": "TTP_MOUSE", "id": "P22893-1", "name": "mRNA decay activator protein ZFP36", "aln": "MDLSAIYESLQS---------------MSHDL--SSDHGGTESL-----GGLWNINS-DSIPSG----------------VTSRLTGRSTSLVEGRSCG-WVPPPPGFAPLAPRPGPELSPSPTSPTATPTTSSRYKTELCRTYSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPTEDLALPGQPHVLRQSISFSGLPSGRRSSPPPPGFSGPSLSSCSFSPSSSPP---PPGDLPLSPS--AFSAAPGTPVTRRDPNQACCPSCRRSTTPSTIWGPLG--GLARSPSAHSLGSDPDDYASSGSSLGGS-------------DSPVFEAGVFGPPQTPAPP----------------------------------------------RRLPIFNRISVSE-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47973-1", "uniprot_id": "TTP_RAT", "id": "P47973-1", "name": "mRNA decay activator protein ZFP36", "aln": "MDLSAIYESLMS---------------MSHDL--SPDHGGTESS-----GGLWNINSSDSIPSG----------------VTSRLTGRSTSLVEGRSCS-WVPPPPGFAPLAPRPGPELSPSPTSPTATPTTSSRYKTELCRTYSESGRCRYGAKCQFAHGPGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPTEDLALPGQPHVLRQSISFSGLPSGRRTSPPPPGFSGPSLSSCSFSPSSSPP---PPGDLPLSPS--AFSAAPGTPVSRRDPTPACCPSCRRSTTPSTIWGPLG--GLARSPSAHSLGSDPDDYASSGSSLGGS-------------DSPVFEAGVFGPPQPPAPP----------------------------------------------RRLPIFNRISVSE-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26651-1", "uniprot_id": "TTP_HUMAN", "id": "P26651-1", "name": "mRNA decay activator protein ZFP36", "aln": "MDLTAIYESLLS---------------LSPDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSG----------------VTSRLPGRSTSLVEGRSCG-WVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAPGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPP---PPGDLPLSPS--AFSAAPGTPLARRDPTPVCCPSCRR-ATPISVWGPLG--GLVRTPSVQSLGSDPDEYASSGSSLGGS-------------DSPVFEAGVFAPPQPVAAP----------------------------------------------RRLPIFNRISVSE-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47976-1", "uniprot_id": "CTH1_YEAST", "id": "P47976-1", "name": "mRNA decay factor CTH1", "aln": "---MMPNVAPNS---------------YYLNIPNANSTSTTTSSIFSDLNKEYESKIKEIEEYY----------------IKTLLNENTDNDDSSSSEGHNINETDILSEYSPRPSPWLPSKPNCYHPLGDFKDLIISDSRPTNTLPINNPFAGNNNIST-LATTEKKRKKRSLEVEINPTYTTSAFSLPLTAENLQKLSQVDSQSTGLPYTLPIQKTTKLEP-CRRAPLQLPQLVNKTLYKTELCESFTIKGYCKYGNKCQFAH--GLNELKFKKKSNNYRTKPCINWSKLGYCPYGKRCCFKH-GDDKDVEIYQNANDGRSKDTALTPLPTS-------------LAPSNNDNITNLSKPRNLH----------------------------------------------TSVKALQRMTW-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47977-1", "uniprot_id": "CTH2_YEAST", "id": "P47977-1", "name": "mRNA decay factor CTH2", "aln": "MWAQLSYTRPES---------------QKTDLTSLFSTDQEQNPLN---DYQYQINIRELEEYY----------------NKTILNE--DNIQETSS--------EISSAVSFSP----PKNTNAIQPG------LLYDP------QLMNPFLPSAHLNS-TAPTTFKKK---LEVQINPDYVPKSSQLPLTSQNLQQLSQQKPKND---ASFSSEKESSAQP-KVKSQVQETP---KQLYKTELCESFTLKGSCPYGSKCQFAH--GLGELKVKKSCKNFRTKPCVNWEKLGYCPYGRRCCFKH-GDDNDIAVYVKA--GTYCNVSSTSKQSD-------------EKRSNG---RGSAKKKNLN----------------------------------------------VKVKALQRMTW-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8M1NCY5-1", "uniprot_id": "A0A8M1NCY5_DANRE", "id": "A0A8M1NCY5-1", "name": "mRNA decay activator protein ZFP36", "aln": "-MSDTFGESLMR---------------NFYNLGLDDSFPNLSSSSDRLIDDCWPVDSWSDRAPS----------------KPQFPIKADRSMSLNDSFS-------RMKPHDVPPPPGFPPLATLPSNR------YKTELCRSFQEHGSCKYGAKCQFAHGENELRGLYRHPKYKTQACRTFYQFGYCPYGSRCHFIHEEKSSLSEQN-PRQLRQSVSFAGFT---RSSSPPSSYESLSFTR-APSVSPPPEEILSPVFSDSSRD--MFSFSRHSSGDIHNSALFAPETRSRCVCGHGNNFPVSGGGLYIKVELKKAPLQRFSSEDSLSDRESY-------------SSTGSSSGSESPTFDGSTG----------------------------------------------KRLSVFARMSVSD-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47980-1", "uniprot_id": "TIS11_DROME", "id": "P47980-1", "name": "Protein TIS11", "aln": "MSADILQKSREQDDSHYFERGDISKYVTMNDHLGDFDCNEVRKEIRMLLAHGANLDQQHQQQPHRHHGGLTRTISQPAQLIQQQQQQHQQQQQQQPAVASLVTITENLGNMNLHRKLERTQSEPLPPQQPMNTSRYKTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRHPKYKTEYCRTFHSVGFCPYGPRCHFVHNADEARAQQAAQAAKSSTQSQSQSQQSSSQNFSPKSNQSSNQSSNSSSSSSSSGGGGGGGNSINNNNGSQFYLPLSPPLSMSTGSDRESPTGSLSLSPTNSLTSFPFHDALQHGYLASNGAKSNSSASSTSSASGMGLGMSMGIGQGMIIGQGLGMGHHGPATPPESPNVPISPVHTPPPYDVVVSGSGAGNNSVGSKQLLQKSVSTPMQQEDTPRLPVFNRLSSGVEAYQQQSNLGL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . : . : : . :: : :.: : . . :: : . * . : . . : : . : : *:: ", "identical_positions": 2, "similar_positions": 34, "identity": "0.46%" }, { "cls_id": "homologset.agr.RGD:620723", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88553-1", "uniprot_id": "ZFP37_RAT", "id": "O88553-1", "name": "Zinc finger protein 37", "aln": "---------------------------------MATPEPAESDA----EWEQLEPGQRNLYKDTKLETCSNPASMGNQDPKQGLVSKLDGEEERWSSVRANKNSSSSLH---RLKKTGTSAKVQQDGAQTEGKQKFQRKLTSEVTFRKKSSNSKKSSECTLLEKKN-VHSKHDPSEKRLHKSNLYGKNLNQNLDLPSQIKISAKKKPDTANEYRKSLSHSASDVNRDEISTRKKCDKSPNNKLFGKGDKNQTGKKCEKVCRHTASHTKEDKIHTGEKR-KSPCRSPS-KSDKAPGSGKPYECNQCGKVLSHKQGLLDHQRTHAGEEPYECYECGIAFSQKSHLVVHQKTPTGEKAPYECVQCGKAHGHKHALTDHLRISHTGEKPYKCNECGKTFRHSSNLMQHIRSHTGEKPYECKECGKSFRYNSSFTEHVRTHTGEIPYECNECGKAFKYGSSLTKHMRIHTGEKPFECTECGKTFSKKSHLVIHQRTHTKEKPYKCKECGKAFGHSSSLTYHMRTHTGDCPFECNKCGKAFKQIEGLTQHQRVHTGEKPYECVECGKAFSQKSHLIVHQRTHTGEKPFECYECGKAFNAKSQLVIHQRSHTGEKPYKPYECVECGKAFKQNASLTRHMKTHSEEQSQEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17141-1", "uniprot_id": "ZFP37_MOUSE", "id": "P17141-1", "name": "Zinc finger protein 37", "aln": "---------------------------------MATSEPAESDAVRAKEWEQLEPVQRDVYKDTKLENCSNPASMGNQDPKQDIVSVLEEEEP--SSGKGKKASPSSLKKIARPKTAGTSAKLQQDDEHREEKQKSQSKLTKEVTLRKKSSNSKKSSEYGLLENKS-LHSKHTPSEKKLLKSSSRGKNSNQNSD-------SLKKKPDTANDHRKSLSHSASDVNKDEIPTRKKCDKLPNNKLSDKGDKNQTSKKCEKVCRHSASHTKEDKIQTGEKR-KSHCRTPS-KPEKAPGSGKPYECNHCGKVLSHKQGLLDHQRTHTGEKPYECNECGIAFSQKSHLVVHQRTHTGEK-PYECEQCGKAHGHKHALTDHLRI-HTGEKPYKCNECGKTFRHSSNLMQHLRSHTGEKPYECKECGKSFRYNSSLTEHVRTHTGEIPYECNECGKAFKYGSSLTKHMRIHTGEKPFECNECGKTFSKKSHLVIHQRTHTKEKPYKCDECGKAFGHSSSLTYHMRTHTGDCPFECNQCGKAFKQIEGLTQHQRVHTGEKPYECVECGKAFSQKSHLIVHQRTHTGEKPFECYECGKAFNAKSQLVIHQRSHTGE---KPYECIECGKAFKQNASLTKHMKIHSEEQSEEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6Q3-1", "uniprot_id": "ZFP37_HUMAN", "id": "Q9Y6Q3-1", "name": "Zinc finger protein 37 homolog", "aln": "MSVSSGVQILTKPETVDRRRSAETTKEAGRPLEMAVSEPEASAA----EWKQLDPAQSNLYNDVMLENYCNQASMGCQAPKPDMISKLEKGEAP-WLGKGKRPSQGCPSKIARPKQKETDGKVQKDDDQLENIQKSQNKLLREVAVKKKTQAKKNGSDCGSLGKKNNLHKKHVPSKKRLLKFESCGKILKQNLDLPDHSRNCVKRKSDAAKEHKKSFNHSLSDTRKGKKQTGKKHEKLSSHSSSDK--CNKTGKKHDKLCCHSSSHIKQDKIQTGEKHEKSPSLSSSTKHEKPQACVKPYECNQCGKVLSHKQGLIDHQRVHTGEKPYECNECGIAFSQKSHLVVHQRTHTGEK-PYECIQCGKAHGHKHALTDHLRI-HTGEKPYECAECGKTFRHSSNLIQHVRSHTGEKPYECKECGKSFRYNSSLTEHVRTHTGEIPYECNECGKAFKYSSSLTKHMRIHTGEKPFECNECGKAFSKKSHLIIHQRTHTKEKPYKCNECGKAFGHSSSLTYHMRTHTGESPFECNQCGKGFKQIEGLTQHQRVHTGEKPYECNECGKAFSQKSHLIVHQRTHTGEKPYECNECEKAFNAKSQLVIHQRSHTGE---KPYECNECGKTFKQNASLTKHVKTHSEDKSHE--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **..** * * **:**:* * ::*:*. **. .* **** * ** .::* *: * :.:: * .. * * *..*:*:*. : * ** * ** **:.:**:. .*:.*: * :*. :*.** **:*:* * . ** :** * . *:*.*:*::::**:.** **..:.: * ** :* ..:. .* *:*.** :*:* *::** *:***:****: ** . :.* * :*. .. ******:***********:****.*:**:**** ****************:* **** **** ****************** *******:* ************:**:***********************:************************.******************.****:*******:**************.*********************:.*****:***.********************** ************************:** ** ******************* ***** ****:********:*:* ***::*.* ", "identical_positions": 403, "similar_positions": 106, "identity": "62.58%" }, { "cls_id": "homologset.agr.RGD:620724", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N961-1", "uniprot_id": "ABTB2_HUMAN", "id": "Q8N961-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGTYSSTLKTLEDLTLD-------------SGYGAGDSCRSLS---------------------------------LSSSKSNS-----------------------------------QALNSSAQQHRGAAWWCYSGS-MNSRHNSWDTVNTVLPEDPEVADLFSRCPR---------------------------------------------------------------------------------LPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYN-GGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGASPARQARQPPQPITWSPDALHTLYYFLRCPQMESME-NPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPEHCFSSFRRLDARAATEKFN-------------------------QDLG--------FRMLNCGRTDLINQAIEALGPDG-VNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSN-SPRHPSIHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNGGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEAHGMGSSLHEDMNCFS---HSAAHGHRNVLRKLLTQPQQ-AKADVLSLEEILAEGVE-ESDASSQGSGSEGPVR--------------LSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLRDFSSIREEEYNEELVTEGLQLMFDILKTSKNDSVIQQLATIFTHCYGSSPIPSIPE---IRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDMKYHIFQMMMQYLYYGGTESMEIPTTDILELLSAASLFQLDALQRHCEILCSQTLSMESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQ-DAFRQLIYGRSSKVQGLDP--LQDLQNTLAER-------VHSVYITSRV-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TQI7-1", "uniprot_id": "ABTB2_MOUSE", "id": "Q7TQI7-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGTYSSTLKTLEDLTLD-------------SGYGAGDSCRSLS---------------------------------LSSSKSNS-----------------------------------QALNSSAQQHRGAAWWCYSGS-MNSRHNSWDTVNTVLPEDPEVADLFSRCPR---------------------------------------------------------------------------------LPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYN-GGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESME-NPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSPTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFN-------------------------QDLG--------FRMLNCGRTDLISQAIEALGPDG-VNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSH-SPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEEMNCFS---HSAAHGHRNVLRKLLTQPQQ-AKADVLSLEEILAEGVE-ESDTSSQGS-SEGPVR--------------LSRTRTKALQEAMYYSAEHGYLDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLKDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPE---IRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQ-DAFRQLIYGRSSKVQGLDP--LQDLQSTLAER-------VHSVYVTSRV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08764-1", "uniprot_id": "ABTB2_RAT", "id": "O08764-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGTYSSTLKTLEDLTLD-------------SGYGAGDSCRSLS---------------------------------LSSSKSNS-----------------------------------QALNSSAPQHRGAAWWCYSGS-MNSRHNSWDTVNTVLPEDPEVADLFSRCPR---------------------------------------------------------------------------------LPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYN-GGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESME-NPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFN-------------------------QDLG--------FRMLNCGRTDLISQP-SSPGPDG-VNTMDDQGLTPLMYACATGDEAMVQMLIDAGANLDIQVPSN-SPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEDMNCFS---HSAAHGHRNVLRKLLTQPQQ-AKADVLSLEEILAEGVE-ESDTSSQGS-SEGPVR--------------LSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQGLLRDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPE---IRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDNSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQ-MPS-----GSSS------------MAEAAKSR-------AWTHCRICRAP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3AP57-1", "uniprot_id": "A0A8M3AP57_DANRE", "id": "A0A8M3AP57-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGTNSSNMKTLEDLTLD-------------SGYGAGDSCKSLS---------------------------------LSSSKSNS-----------------------------------QAFMN--TPHRG-NWWYYSGS-MNSRNNSWDTVNTVLPEDP--EDIFSKCPR---------------------------------------------------------------------------------LPELEEFPWTEEDVGRVVRKGAG--KGASFSAEAVRRLATLMRRALIRISREAQRLSVMHCRCTKFEVQSAIRLVLSWALADHCVSATVKAISMYNMSAGELLRKGKSARCGLVFSVGRFFRWMVDTRIAVRIHEYAAICLSACMEALVEEVGVRILMAERE--GATPGCVLTAETLEGVINNDAELWGVLQHHEHLICGKNANGVLSLPAHFSPYTEGRQTGLETREDAYAELELRTLEQALLATCVGSISELSDLVSRAMHHMQRLSSVRHGLSPARHARQ--QPVSWSPDALHTLYYFLRCPQMESME-NPNLDPPRMALSKERPFLLLPPLMEWMRVAIVHAEHRRSLLVDSDDVRQTARLLLPGLDCEPRLLKPECCFSSFRRLDAKAATDKFQ-------------------------LDLG--------FRMLNCGRTDLIGQAIELLGPDG-VNSMDDQGMTPLMYACSAGDEALVQMLIDAGANLDVAVPMC-SPKHPSVHADSRHWVALTFAVLHGHISVAQLLLDAGANVEGAAIRYGQENTSETPLQLASAAGNYEMVSLLLARGADPLLRSQDSNTLTSSLYEDMNCFS---HAAAHGHRNVLRKLLSQPQK-VREDVLSLEEILAEGVDGETQASGRNGHSLPPPPSPNLSLVSEDALPKLCKTRMKALQEASFYSAEHGYLDVTMELRSLGVPWKLHVWLESLRSAQQKSRAGVMLSLLRDFTSVKEEDYCEELVSVGLPLMFNILKNSKNEAIIQQLGIIFSHCYGTAPLPPIQE---KKAALAAQLDPHFLNNQEMSDVTFLVEGKPFYAHGVLLLTASDRFKTLLAQNGSDSTQTRKDIEISNIKYNIFQMMMSYLYCGGTESLKMGVSELLELLSAASLFQLGVLQRHCEILCAQNIDLDNAVNIYHTAKANGAVELSTYCEGYFLQNMAVLLER-EAFRVMILGSGARSGSGKDSLLEALEATLVRR-------LRSLLVTSRV-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PFY3-1", "uniprot_id": "M9PFY3_DROME", "id": "M9PFY3-1", "name": "BTB domain-containing protein", "aln": "MYCTKDCTCSLCRELRGYKPSDKKSAPSAPTLLSRMLNDNFILRRRGISLKNFQPQSLRNSEMLAQQMPVPRPPQTPSPTPIEELPDWATEDSSRAKKPNHKVVIYFGDSIHRGGQQSPLPSPKELHSQLLQEMSQKLKTSVAEEGLTGVEKVKKVQQMAGQPETSPPANDELPPYIESVQNGVINIRIEGNYRRASALVETVAKPTLAVVAPTKSECDCDAALGDNDDGNADDDSDDPGQDEAETDSCDWSYVQEWRRAAKRPTGNLPPNFVQHQAPSQVTGLPPVPPPQMQSPHQVQSQLPPSQTPLSSQKGLAVAMATPAPRVFKELAQQPNKGMPHKMVASSSSCSGGQANSSCKMPSPGTASKALIPQRAVAGPARLTVQSTPVKSQPPQLSGSLSQSQVSPNRPILGIPTTAANPTPPRIHQHDQFRALQRVQECHSSSDENRSSGHASMSDTGGHSSSPAGGMTLGPLPEDRLAAGVTNRSTRSRRHRGIMPGGKAPWSGTGLEDIKLAMLTLRSQTSSSTYSSLSAGSESSEPARRLGRYSSLETVVTSTSADEFVWVDSHNRLVELQHPPWSQQCILKVLRNGRCQQQAEHLAVEAVSRLGYLLQRALVRIAREIQRFSAGVGLCSKQEVVGALRVVLSSSLADSCTKACLRSAAMFAVPGESALKQSKSARAGLQLSVGRFYRWMTDARLGKFIHEYAAVYLCAGIENLLEEIALQCNG-------------TTAAALDQSIASSGDVWGLLQPFAHLNAGRIASGALALPRWANSLDQVIASSGDFRG--------------HLATCVGSIRELKEKALRTQQEFQLAAALSGSALAALFYFMRCSQLEHTELLAASGCHAGQAQSAAPGGGTSSAGHHVQELCYERAYVVLPPLAEWLRVAAAHAEHRNAMMIDKDDVMQAARLLLPGVDCPIRPVAHDEELPTKKTHFNTAPTVSSTGTGTGSSSCSSPVVSGIGIGIGEDTSELGRRATIGVAFKLLLTGRAELLAQAAQLLPPTTRYDTQNSAGLTALMIASIRNDEVALHALLDAGCDPNVEVPPAGSAGYPAIQPDTQHWTALSFAASRANYVALRILLERGGKVEGGARSS-EEKCTLTPLQLAAGTGNLEIVALLLAHGANAFLSTQQKDSLCFAGSAQKGCFCAISVAAAHGHRSCLRKLLTHPVSPGTRDVLSLEEMLAEGDVGGVRGSGGPTGAGGPNS-ASASGNNEDILPLLNKTQIKRLQEAMYHSAENNHLDITIELRKLGVPWTLHCWMHALSAAHDLRLDAVIDQLLQDFLQVCPDDYSAQFVSECLPLLFNIFRN-KNEGTTLLLADIFATCFGWETLPPVKEQPPMQPVQGSRIDPKFVNNPELSDVTFRVEGKIFYGHKIVLVTASPRFQSMLSSKLSE-GSSTPTVQINDIRYHIFQLVMQFLYCGGCSSLDVAHGDVLELMAAASFFQLEGLLRYTEARCSEMVDVDNVVAMYIHAKVYNANRLLEFCQCFLLQNMVALLTYDDSVKRLLFAKKIPNHDVLAGLLQTLQNRLKARKPNSGGGLVNSYRSPPVTPVKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 328, "similar_positions": 329, "identity": "20.76%" }, { "cls_id": "homologset.agr.RGD:620726", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88181-1", "uniprot_id": "BARH2_RAT", "id": "O88181-1", "name": "BarH-like 2 homeobox protein", "aln": "--------------------------------MTAMEGASGSSFGIDTILSGAGSGSPGMMNGDFRSLGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHHHLHHGQQPPPPSAPPAQSLQ---------------------------------------------------PSPQQQ---PPPQPQS-AAQQLG--------------------------------------------------------SAAAAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQECNAAHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRES--------PPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSP-----------------------------YFYHPSLLGSMDST----------------------------TAAAAAAAMYSSMYR---------TPPAPHPQLQRPLVPRVLIHG------------LGPGGQPALNPLSNPIPGTPHPR---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIB5-1", "uniprot_id": "BARH2_MOUSE", "id": "Q8VIB5-1", "name": "BarH-like 2 homeobox protein", "aln": "--------------------------------MTAMEGASGSSFGIDTILSGAGSGSPGMMNGDFRSLGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHHHLHHSQQPPPPSAVPAQSLQ---------------------------------------------------PSPQQQ---PPPQPQS-AAQQLG--------------------------------------------------------SAAAAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAAHESFRPKLEQEDGKTKLDKREDPQSDIKCHGTKEEGDREITSSRES--------PPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSP-----------------------------YFYHPSLLGSMDST----------------------------TAAAAAAAMYSSMYR---------TPPAPHPQLQRPLVPRVLIHG------------LGPGGQPALNPLSNPIPGTPHPR---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY43-1", "uniprot_id": "BARH2_HUMAN", "id": "Q9NY43-1", "name": "BarH-like 2 homeobox protein", "aln": "---------------------------------MTMEGASGSSFGIDTILSSASSGSPGMMNGDFRPLGEARTADFRSQATPSPCSEIDTVGTAPSSPISVTMEPPEPHLVADATQHHHHLHHSQQPPPPAAAPTQSLQ---------------------------------------------------PLPQQQQPLPPQQPPPPPPQQLG--------------------------------------------------------SAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAVHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRES--------PPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSP-----------------------------YFYHPSLLGSMDST----------------------------TAAAAAAAMYSSMYR---------TPPAPHPQLQRPLVPRVLIHG------------LGPGGQPALNPLSSPIPGTPHPR---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24256-1", "uniprot_id": "BARH2_DROME", "id": "Q24256-1", "name": "Homeobox protein B-H2", "aln": "MTTMPPEMSATTAAPVGSAPSATAHHPAAVGGGMPRPASPAVGSNTTTATATTATRSRFMITDILAGAAAASAAAAAAAAALAAASSGGGRGSPTDSEREQSLVAQHHHHHQQQQQHHHHQQQQQQQQHQQAALQQYIVQQQQLLRFEREREREREREHYRERHSPPGNNPYAHHPMPPHLLAHFPPAHYAVLQQQQQQQQQQQHPHPHHLQLERERLEALHRHGHGLTGDPAQHLSHLSHLSHQQHHPHLHHPMHDERSRSPLMLQQLGGNGGNNNNNNNNSSSASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQASTIDDSDSDDCGGKDDDGDDSMKNGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAAAQSPHGATP-SAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPGMSLPGMPAPP----PPGAAPMLSGYY--AAAAAAAASAGAQQQQQQPPAASRSPATSQSANSEADCERTSSSSRQRLITPSPPLNPGSPPHRERINEEEDRERDEERDIERERERERERDEDDEEELALEV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24255-1", "uniprot_id": "BARH1_DROME", "id": "Q24255-1", "name": "Homeobox protein B-H1", "aln": "---MKDSMSILTQTPS-----------------EPNAAHPQLHHHLS--TLQQQHHQHHLHYGLQPPAVAHSIHSTTTMSSGGSTTTASGIGKPNRSRFMINDILAGSAAAAFYKQQQHHQQLHHHNNNNNSGSSG-----------------GSSPAHSNNNNNINGDNCEASNVAGVGVLP-------SALHHPQPHPPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAM-----QQHY------------------AAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGN----MDDHSVCSNGGKDDDGN-SVKSGSTS--DMSG-----LSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGS-PYLGAWPYAAAAGAA--HGATPHTNIDIYYRQAAAAAAMQKP-LPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAAAASAANPGGPHPVAPPPSVGGGSPPSGLVKPIPAHSASASPPPRPPSTPSPTLNPGSPPGRS---------------------VDSCSQSDDEDQIQV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : . : :: .. : . *.. * . *::** : :: : . :: : . . .. .. ... : . . .. :. . . . . . . * . . *..::*: .:... : :** *******:****: **:***********:* :** *:*:* *****************************::*:**:: .. *: :.: .:*:.. ...: . *. * .. . : * . . .. : .* . **:* * ", "identical_positions": 82, "similar_positions": 103, "identity": "12.58%" }, { "cls_id": "homologset.agr.RGD:620727", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89051-1", "uniprot_id": "ITM2B_MOUSE", "id": "O89051-1", "name": "Integral membrane protein 2B", "aln": "-MVKVTFNSALAQKEAKKDEPKSSEEALIVPPDAVAVDCKDPG---DVVPVGQRRAWCWCMCFGLAFMLAGV-----ILGGAYLYKYFALQPDDVYY---CGLKYIKDDVILN----------------------EPSADAPAARYQTIEENIKIFEE-DAVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPKNLLELLINIKAGTYLPQSYLIHEHM-VITDRIENVDNLGFFIYRLCHDKETYKLQRRETIRGIQKREAS---NCFTIRHFENKFAVETLICS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y287-1", "uniprot_id": "ITM2B_HUMAN", "id": "Q9Y287-1", "name": "Integral membrane protein 2B", "aln": "-MVKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPD---DVVPVGQRRAWCWCMCFGLAFMLAGV-----ILGGAYLYKYFALQPDDVYY---CGIKYIKDDVILN----------------------EPSADAPAALYQTIEENIKIFEE-EEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHM-VITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGIQKREAS---NCFAIRHFENKFAVETLICS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XIE8-1", "uniprot_id": "ITM2B_RAT", "id": "Q5XIE8-1", "name": "Integral membrane protein 2B", "aln": "-MVKVTFNSALAQKEAKKDEPKSSEEALIAPPDAVAVDCKDPD---DVVPVGQRRAWCWCMCFGLAFMLAGV-----ILGGAYLYKYFALQPDDVYY---CGLKYIKDDVILS----------------------EPSADAPAARYQTIEENIKIFEE-DAVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHM-VITDRIENVDHLGFFIYRLCHDKETYKLQRRETIRGIQKREAS---NCFTIRHFENKFAVETLICS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VPT9-1", "uniprot_id": "Q9VPT9_DROME", "id": "Q9VPT9-1", "name": "Integral membrane protein 2", "aln": "MTILGKLRGQPTDQEKVPLPMNLNDEALMHHGSLIAPKVAYSDNEADAESMVFNRPQHHCIKSFLLFLIAVVVMLLGVLGGWTLYRVYAPSHSSMRYHALCEIPYPEDSMEMARVYPRTVEPFALNWRSLLPELAQPMPNSGSLDESHFREDIELDGDSDDEGYARVDVPDFKDGRRGRFMHDFKENQSAIIDTTTGRCFIMPLDRDTTLPPTSFVDLIKKMSTGYYNIDTERVRRQMRVVMPRITDVSLISERIANECFDMKVYMMEK--FVSGVSKRSADPLPESAKYAEFMGKGVIEYDLANIAEVEAYEANEARQQA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.. :::* : .:***: . :* . .. *. .: .*. *: * *::* * :*** **: :* . ..: * * : * :*.: : :* .:: : . :.*:*:: : : : * **:* *. ..::***::: :* :* . .:*:::**: . .:** .:::*: ::.:* * :: ::.:* *: ** ::. :. * . *.* :.* ::: : *:.**.*. :. .* .* .:* :.. ", "identical_positions": 58, "similar_positions": 114, "identity": "18.07%" }, { "cls_id": "homologset.agr.RGD:620728", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIN6-1", "uniprot_id": "KCMB4_MOUSE", "id": "Q9JIN6-1", "name": "Calcium-activated potassium channel subunit beta-4", "aln": "MAKLRVSYEYTEAEDKSIRLGLFLIVSGILSLFIFGFCWLSPALQDLQATAANCTVLSVQQIGEVFECTFTCGTDCRGTSQYPCVQVYVNNSESNSRALLHSDQHQLLTNPKCSYIPPCKRENQKNSESVMNWQQYWKDEIGSQPFTCYFNQHQRPEDVLLQRTHDEIALLHCFLWPVVAFVVGVLIVVLTICAKSLAVKAEAMKKRKFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ESK8-1", "uniprot_id": "KCMB4_RAT", "id": "Q9ESK8-1", "name": "Calcium-activated potassium channel subunit beta-4", "aln": "MAKLRVSYEYTEAEDKSIRLGLFLIVSGILSLFIFGFCWLSPALQDLQATAANCTVLSVQQIGEVFECTFTCGTDCRGTSQYPCVQVYVNNSESNSRALLHSDQHQLLTNPKCSYIPPCKRENQKNSESVMNWQQYWKDEIGSQPFTCYFNQHQRPEDVLLQRTHDEIVLLHCFLWPVVAFVVGVLIVVLTICAKSLAVKAEAMKKRKFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86W47-1", "uniprot_id": "KCMB4_HUMAN", "id": "Q86W47-1", "name": "Calcium-activated potassium channel subunit beta-4", "aln": "MAKLRVAYEYTEAEDKSIRLGLFLIISGVVSLFIFGFCWLSPALQDLQATEANCTVLSVQQIGEVFECTFTCGADCRGTSQYPCVQVYVNNSESNSRALLHSDEHQLLTNPKCSYIPPCKRENQKNLESVMNWQQYWKDEIGSQPFTCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPLVTFVVGVLIVVLTICAKSLAVKAEAMKKRKFS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:******************:**::******************** **********************:*****************************:********************** *****************************:****:******.********:*:******************************", "identical_positions": 197, "similar_positions": 11, "identity": "93.81%" }, { "cls_id": "homologset.agr.RGD:62073", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51577-1", "uniprot_id": "P2RX4_RAT", "id": "P51577-1", "name": "P2X purinoceptor 4", "aln": "---MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKAKGVAVTNTSQLGFRIWDVADYVIPAQEENSLFIMTNMIVTVNQTQSTCPEIPDKTSICNSDADCTPGSVDTHSSGVATGRCVPFNESVKTCEVAAWCPVENDVGVPTPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNAQTDPFCPIFRLGTIVEDAGHSFQEMAVEGGIMGIQIKWDCNLDRAASLCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYYRDLAGKEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYCMKKKYYYRDKKYKYVEDYEQGLSGEMNQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJX6-1", "uniprot_id": "P2RX4_MOUSE", "id": "Q9JJX6-1", "name": "P2X purinoceptor 4", "aln": "---MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRVVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKAKGVAVTNTSQLGFRIWDVADYVVPAQEENSLFIMTNMIVTVNQTQGTCPEIPDKTSICDSDANCTLGSSDTHSSGIGTGRCVPFNASVKTCEVAAWCPVENDAGVPTPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNARTDPFCPIFRLGQIVADAGHSFQEMAVEGGIMGIQIKWDCNLDRAASHCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYYRDLAGNEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYCMKKRYYYRDKKYKYVEDYEQGLSGEMNQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99571-1", "uniprot_id": "P2RX4_HUMAN", "id": "Q99571-1", "name": "P2X purinoceptor 4", "aln": "---MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYCMKKRLYYREKKYKYVEDYEQGLASELDQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W463-1", "uniprot_id": "P2X4A_DANRE", "id": "F8W463-1", "name": "P2X purinoceptor 4a", "aln": "MSESVGCCDSVSQCFFDYYTSKILIIRSKKVGTLNRFTQALVIAYVIGYVCVYNKGYQDTDTVLSSVTTKVKGIALTNTSELGERIWDVADYIIPPQEDGSFFVLTNMIITTNQTQSKCAENPTPASTCTSHRDCKRGFNDARGDGVRTGRCVSYSASVKTCEVLSWCPLEKIVDPPNPPLLADAENFTVLIKNNIRYPKFNFNKRNILPNINSSYLTHCVFSRKTDPDCPIFRLGDIVGEAEEDFQIMAVHGGVMGVQIRWDCDLDMPQSWCVPRYTFRRLDNKDPDNNVAPGYNFRFAKYYKNSDGTETRTLIKGYGIRFDVMVFGQAGKFNIIPTLLNMGAGLALLGLVNVICDWIVLTFMKRKQHYKEQKYTYVDDF--GLLHNEDK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*** :. :*:* *.:*::***:*** :** .* *::*****:* *::****:**:*:******.**:*:****:** ********::*.**:.*:*::**:*:* ****. *.* * :: * *. .*. * .::..*: *****.:. ******* :***:*. . * *.:* *****:*:**** ******.********.::**. *::. :*** ******* ** :* ..** ***.**:**:*:.***:** . * *:***:*****.:* ::**:***********:: *.* *** *.******::***:****:****::*:*:******:..*:** *** **:: :*:::**.**:*: ** : ::", "identical_positions": 220, "similar_positions": 112, "identity": "56.27%" }, { "cls_id": "homologset.agr.RGD:620730", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z252-1", "uniprot_id": "LIN7B_RAT", "id": "Q9Z252-1", "name": "Protein lin-7 homolog B", "aln": "MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEVRAHATAKATVAAFTASEGHAHPRVVELPKTDEG---------------------------------------------------LGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARRRQQHHSYSSLESRG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88951-1", "uniprot_id": "LIN7B_MOUSE", "id": "O88951-1", "name": "Protein lin-7 homolog B", "aln": "MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEVRAHATAKATVAAFTASEGHAHPRVVELPKTDEG---------------------------------------------------LGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARRRQQHHSYTSLESRG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAP6-1", "uniprot_id": "LIN7B_HUMAN", "id": "Q9HAP6-1", "name": "Protein lin-7 homolog B", "aln": "MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEG---------------------------------------------------LGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARRRQQHQSYSSLESRG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N6F0-1", "uniprot_id": "A0A8M1N6F0_DANRE", "id": "A0A8M1N6F0-1", "name": "Protein lin-7 homolog", "aln": "MAAMTEPLCLERDVCRVIELLDRLQRSGQLPPPKLQALQRVLQSKFCAAIREVYEQLYDTLDIIGGPEVRAQATAKATVAAFAASEGHAHPRVVELPKTDEG---------------------------------------------------LGFNIMGGKEQNSPIYISRVIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPKVLEEMEARFEKMRSARRRQQHTSYSSLESRG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMT8-1", "uniprot_id": "Q8IMT8_DROME", "id": "Q8IMT8-1", "name": "Protein lin-7 homolog", "aln": "MADNAEPLTLSRDVKRSIELLEKLQASGDFPTTKLAALQKVLNSDFMTSVREVYEHVYETVDIQGSHDVRASATAKATVAAFAASEGHAHPRVVELPKTEEGKTRPYELRIEGIPLYHKTNTLIVKVYRPRIYVSIIHLIWKALSIFNFCFSGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLKQAVGSVKLVVRYTPKVLEEMEMRFDKQRNTRRRQ------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .*** *.*** * :***::** **::*. ** ***:**:* * :::*****::*:*:** *. ::** **********:****************:** ****:**************:********:********************:********* * ***********:****** **:* *.:**** ", "identical_positions": 148, "similar_positions": 30, "identity": "57.36%" }, { "cls_id": "homologset.agr.RGD:620731", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70355-1", "uniprot_id": "BTNL2_MOUSE", "id": "O70355-1", "name": "Butyrophilin-like protein 2", "aln": "MVDCPRYSLSGVAASFLFVLLTIKHPDDFRVVGPNLPILAKVGEDALLTCQLLPKRTTAHMEVRWYRSDPDMPVIMYRDGAEVTGLPMEGYGGRAEWMEDSTEEGSVALKIRQVQPSDDGQYWCRFQEGDYWRETSVLLQVAALGSSPNIHVEGLGEGEVQLVCTSRGWFPEPEVHWEGIWGEKLMSFSENHVPGEDGLFYVEDTLMVRNDSVETISCFIYSHGLRETQEATIALSERLQTELASVSVIGHSQPSPVQVGENIELTCHLSPQTDAQNLEVRWLRSRYYPAVHVYANGTHVAGEQMVEYKGRTSLVTDAIHEGKLTLQIHNARTSDEGQYRCLFGKDGVYQEARVDVQVMAVGSTPRITREVLKDGGMQLRCTSDGWFPRPHVQWRDRDGKTMPSFSEAFQQGSQELFQVETLLLVTNGSMVNVTCSISLP-LGQEKTARFPLSG------W---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6MG97-1", "uniprot_id": "BTNL2_RAT", "id": "Q6MG97-1", "name": "Butyrophilin-like protein 2", "aln": "MVDFPGYSLSGVAASFLFVLLTMKHPDDFRVVGPALPILANVGEDALLTCRLLPKRTTARMEVRWYRSDPDTPVMLYRDGAEVPGLAMEGYRGRVEWMEDSTEEGSVALKIRQVQPGDDGQYWCRIQEGDYWREASVLLQVAALGSSPNIHVEGPGEEGVQLVCTSRGWFPEPEVYWEGIRGEKLMSLSENHVYGEDGLFSVEDTLVVRNDSVETISCFIYNRGLREPQEATIALPEKLQTELASSRVIGPSQAIPVRVGETIELTCQLSPQTDAQSLEVRWLRARYYPVVHVYTNGAHEAGEQMAEYRGRTSLVTDAIHEGKLTLQIHNARTSDEGQYRCLFGKDGVYQEARVDVQVMAVGSTPQITREVLKDGGTQLRCTSDGWFPRPHVQWRDRDGRTLPSFSEAFRQGSQELFQVETLLLVTNGSMVNVTCSISLP-LGEEKTARFPLSG------W---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UIR0-7", "uniprot_id": "BTNL2_HUMAN", "id": "Q9UIR0-7", "name": "Butyrophilin-like protein 2", "aln": "MVDFPGYNLSGAVASFLFILLTMKQSEDFRVIGPAHPILAGVGEDALLTCQLLPKRTTMHVEVRWYRSEPSTPVFVHRDGVEVTEMQMEEYRGWVEWIENGIAKGNVALKIHNIQPSDNGQYWCHFQDGNYCGETSLLLKVAGLGSAPSIHMEGPGESGVQLVCTARGWFPEPQVYWEDIRGEKLLAVSEHRIQDKDGLFYAEATLVVRNASAESVSCLVHNPVLTEEKGSVISLPEKLQTELASLKVNGPSQPILVRVGEDIQLTCYLSPKANAQSMEVRWDRSHRYPAVHVYMDGDHVAGEQMAEYRGRTVLVSDAIDEGRLTLQILSARPSDDGQYRCLFEKDDVYQEASLDLKVVSLGSSPLITVEGQEDGEMQPMCSSDGWFPQPHVPWRDMEGKTIPSSSQALTQGSHGLFHVQTLLRVTNISAVDVTCSISIPFLGEEKIATFSLSESRMTFLWKTLLVWGLLLAVAVGLPRKRS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** * *.***..*****:***:*:.:****:** **** *********:******* ::*******:*. **:::***.**. : ** * * .**:*:. :*.*****:::**.*:*****::*:*:* *:*:**:**.***:*.**:** ** ******:*******:*:**.* ****::.**::: .:**** .* **:*** *.*::**:::. * * : :.*:*.*:******* * * **. *:*** *:*** ***:::**.:**** *:: **.**** :* * *****.**:*** **:***.**:***** .**.**:******* **.***** :*::*:::**:* ** * :** * *:******:*** *** :*:*:** *:*: ***: **:*:*** *** * *:******:* **:** * *.** * ", "identical_positions": 277, "similar_positions": 112, "identity": "57.47%" }, { "cls_id": "homologset.agr.RGD:620732", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P34914-1", "uniprot_id": "HYES_MOUSE", "id": "P34914-1", "name": "Bifunctional epoxide hydrolase 2", "aln": "MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITFSQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFP--EAPLPVPCNPNDVSHGYVTVKPGIRLHFVEMGSG--PALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWLQTEVQNPSVTSKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P80299-1", "uniprot_id": "HYES_RAT", "id": "P80299-1", "name": "Bifunctional epoxide hydrolase 2", "aln": "MALRVAAFDLDGVLALPSIAGVLRHTEEALALPRDFLLGAFQMKFPEGPTEQLMKGKITFSQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPMLQAAAALKKKGFTTCIVTNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQIYKFVLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQFP--EAPLPVPCSPNDVSHGYVTVKPGIRLHFVEMGSG--PAICLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWNMALFHPERVRAVASLNTPLMPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRTSDDMGLLTVNKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGPLNWYRNTERNWKWSCKALGRKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDCGHWTQIEKPAEVNQILIKWLKTEIQNPSVTSKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P34913-1", "uniprot_id": "HYES_HUMAN", "id": "P34913-1", "name": "Bifunctional epoxide hydrolase 2", "aln": "MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSG--PAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES-VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53750-1", "uniprot_id": "YN93_YEAST", "id": "P53750-1", "name": "Uncharacterized hydrolase YNR064C", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNIIAR----------------------------------FHKIQVQDGVKVWYREAGAAGNPTILLLHGFPTSSNMFRNLIPLLAGQ-FHIIAPDLPGFG-FTETPENYKFSFDSLCESIGYLLDTLSIEKFAMYIFDYGSPVGFRLALKFPSRITGIVTQNG-----NAYEEGLDDRFWGPLKEYWKSYQSDPVFVKSLIPYLEDPANVICQYHDGVPAIES-----------VDPAAYTLDIALIQRTGQTDIQLRLFFDYQNNIKLYP--------AFQKFLRDSKIPVLVAWGANDTIFSVAGAEAYRKDVDNLKVVYYDTG-HFALETHVVAIAEEIISMFAEN----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*:.: . : *: ::: : * *:. *:: * **** * :* ** ** ::::* *: *:* : .** ::.:: **:.: :*:.*.: : .: .*:.. : : :** .*.*: .:.: * :. . :. *: :* :*. * .* :. . : : : * : * .:. :. : :* .::. :: * : : : *. :*.*:. . :* :: :: .. : ** : : *:: : . : : :*. : : ", "identical_positions": 50, "similar_positions": 113, "identity": "8.96%" }, { "cls_id": "homologset.agr.RGD:620733", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKU1-1", "uniprot_id": "TR119_RAT", "id": "Q9JKU1-1", "name": "Taste receptor type 2 member 119", "aln": "MMEGHILFFFLVVMVQFVTGVLANGLIVVVHAIDLIMWKKMAPLDLLLFCLATSRIILQLCILFAQLCLFSLVRHTLFEDNITFVFIINELSLWFATWLGVFYCAKIATIPHPLFLWLKMRISRLVPWLILGSVLYVIITTFIHSRETSAILKPIFISLFPKNATQVG-TGHATLLSVLVLGLTLPLFIFTVAVLLLIYSLWNYSRQMR-TMVGTREYSGHAHISAMLSILSFLILYLSHYMVAVLISTQVLYLGSRTFVFCLLVIGMYPSIHSIVLILGNPKLKRNAKMFIVHCKCCHCTRAWVTSRSPRLSDLPVPPTHPSANKTSCSEACIMPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKT2-1", "uniprot_id": "TR119_MOUSE", "id": "Q9JKT2-1", "name": "Taste receptor type 2 member 119", "aln": "MMEGHMLFFLLVVVVQFLTGVLANGLIVVVNAIDLIMWKKMAPLDLLLFCLATSRIILQLCILFAQLGLSCLVRHTLFADNVTFVYIINELSLWFATWLGVFYCAKIATIPHPLFLWLKMRISRLVPWLILASVVYVTVTTFIHSRETSELPKQIFISFFSKNTTRVR-PAHATLLSVFVFGLTLPFLIFTVAVLLLLSSLWNHSRQMR-TMVGTREPSRHALVSAMLSILSFLILYLSHDMVAVLICTQGLHFGSRTFAFCLLVIGMYPSLHSIVLILGNPKLKRNAKTFIVHCKCCHCARAWVTSRNPRLSDLPVPATHHSANKTSCSEACIMPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYW7-1", "uniprot_id": "TA2R1_HUMAN", "id": "Q9NYW7-1", "name": "Taste receptor type 2 member 1", "aln": "MLESHLIIYFLLAVIQFLLGIFTNGIIVVVNGIDLIKHRKMAPLDLLLSCLAVSRIFLQLFIFYVNVIVIFFIEFIMCSANCAILLFINELELWLATWLGVFYCAKVASVRHPLFIWLKMRISKLVPWMILGSLLYVSMICVFHSKYAGFMVPYFLRKFFSQNATIQKEDTLAIQIFSFVAEFSVPLLIFLFAVLLLIFSLGRHTRQMRNTVAGSRVPGRGAPISALLSILSFLILYFSHCMIKVFLSSLKFHIRRFIFLFFILVIGIYPSGHSLILILGNPKLKQNAKKFLLHSKCCQ--------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.*:::::*:.::**: *:::**:****:.**** :********* ***.***:*** *::.:: : ::.. : * ::: :****.**:***********:*:: ****:*******:****:**.*::** : .:**: :. : :: .:*.:*:* * : :* :::*::** .*****: ** .::**** *:.*:* . * :**:**********:** *: *::.: ::: * * :****:*** **::*********:*** *::*.***: ", "identical_positions": 144, "similar_positions": 97, "identity": "42.73%" }, { "cls_id": "homologset.agr.RGD:620734", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UQB3-1", "uniprot_id": "CTND2_HUMAN", "id": "Q9UQB3-1", "name": "Catenin delta-2", "aln": "MFARKPPGAAPLGAMPVPDQPSSASEKTSSLSPGLNTSNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLGSETGSMSSMSSAEEQFQWQSQDGQKDIEDELTTGLELVDSCIRSLQESGILDPQDYSTGERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLALGETTPSQLPARGTQARATGQSFSQGTTSRAGHLAGPEPAPPPPPPPREPFAPSLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGATYA-APRGSSPKQSPSRLAKSYSTSSPINIVVSS-AGLSPIRVTSPPTVQSTISSSPIHQLSSTIGTYATLSPTKRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLGPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQG------DPLPPAHTGTYRTSTAPSSPGVDSVPLQRTGSQHGPQNAAAATFQRASYAAGP---ASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLARSPSIDSIQKDPR-------------------EFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWK-------------------------WSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNT----ASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKDAMTAQN-TGISTLYRNSYGAPAEDIKHNQVSAQPVPQEPSRKDYETYQPFQNST-RNYDESFFEDQVHHR-PPASEYTMHLGLKSTGNYVDFYSAARPYSELNYETSHYPASPDSWV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35927-1", "uniprot_id": "CTND2_MOUSE", "id": "O35927-1", "name": "Catenin delta-2", "aln": "MFARKQSGAAPFGAMPVPDQPPSASEKNSSLSPGLNTSNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLGSETGSMSSISSAGEQFHWQTQDGQKDIEDELTTGLELVDSCIRSLQESGILDPQDYSTSERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLALGDTAPSQLPARSTQARAAGQSFSQGTTGRAGHLAGSEPAPPPPPP-REPFAPSLGSAFHLPDAPP--AAAALYYSSSTLPAPPRGGSPLTTTQGGSPTKLQRGGSAPEGAAYA-APRGSSPKQSPSRLAKSYSTSSPINIVVSS-AGLSPIRVTSPPTVQSTISSSPIHQLSSTIGTYATLSPTKRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLAPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQG------DPLPPAHTGTFRTSTAPSSPGVDSVPLQRTGSQHGPQNAAAATFQRASYAAGP---ASNYADPYRQLQYCASVDSPYSKSGPALPPEGTLARSPSIDSIQKDPR-------------------EFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELDGLLCGETNGKDTESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKGWAEDVAGMAYALRSLPEGAPCLPQWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNS----GSKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNNRSASAPASPREMISLKERKTDYESAGNNATYHGTKGEHTSRKDTMTAQN-TGVSTLYRNSYGAPAEDIKQNQVSTQPVPQEPSRKDYETYQPFPNST-RNYDESFFEDQVHHR-PPASEYTMHLGLKSTGNYVDFYSAARPYSELNYETSHYPASPDSWV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35116-1", "uniprot_id": "CTND2_RAT", "id": "O35116-1", "name": "Catenin delta-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKKSQDQWDGVG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB13A7D4-1", "uniprot_id": "A0AB13A7D4_DANRE", "id": "A0AB13A7D4-1", "name": "", "aln": "--------------MPVPDQP-SGTENSSMLSPVLNASNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVATQLERCKLGSETGSMSSISSADEKFRWNNQDGQKDIEEELTTGLELVDSCIRSLQESGILDSQEFTAGERPGILSQSALQLNNQ-EGTFPYPVSYHSNQTLALGDLSASQ-PPRSGQVGGALHSYNQVTSNRVAQLAARETAAR--AHSRDSYAQSHGSAFHMPDDQP---TVPVNYSCATLPAQ-RVSSPFSMQALGSPSKLQRLGSASDMPSYATLARVSSPKQSPSRLAKSYSTSSPINMAAGGGSSSSPLHMAGAGNVS---NSSPLHQLSAAVGSYATLSPTKRMLHTTDQY-KISHDLYANATLQRPGSLAG-SRGSYSSQHSHLGSELRPLQSPEHHIDPIYEDRVYQKAPLRNFNQAQDPMNQFCDQVLNFLLCPYSPVIAPSSPGVDSIPLQRTGSQN-----ATGTFPRAGYATGPGASTADYANPYRTLQFCPSTDSPYSKSGPALPPEATLVRSPSVDSIQKDPRYDPEFLVWNQNQAEQRMTKEFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKSEIRRQGGIQLLVDLLDHRMTDVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDVEIRELLTGVLWNLSSCDALKMPIIQDALAVLTNTVIIPHSGWDTSPLQDDRKLHLHSSQVLRNATGCLRNVSSAGEEARRRMRECEGLTDALLYVIQTALGTSEIDSKTIENCVCILRNLSYRLAAETSQGQQMGSEELDGVLCTDASGKDAESSGCWGKKKKKKKSHDQWDGVGPFPDSSDPPKGLQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKVG------------------PTLKPWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNNNSTGTGGSSKSMSDDTITAICCALHEVITKNMENTKALRDAGGIEKLIGIARSKGDKHTPKVVKAASQVLNSMWQYRDLRSLYKKDGYSQYHFVGSSSTIERDRQRPYSSSRTPSISPVRTSPNNRSASAPTSPREMMSLKERKTDYESTGSNSTYHGNKGEHTSRKDAMAAQISSGTSTLFRGAYMSPADDIKHNQVSAQGNPPE-------AYPPFQTPPGANFEEPYYEDQAHKRPPPAADGTMHLGLKSTGNYVDFYSASRPYSELNYETSHYPASPDSWV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***********************:********************:*******************************************:*****:***************************:********:.********::*******************************:***********:***:*******:**********************:**::****:** ::.***:***************:******* ", "identical_positions": 241, "similar_positions": 22, "identity": "18.73%" }, { "cls_id": "homologset.agr.RGD:620735", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKU0-1", "uniprot_id": "T2R16_RAT", "id": "Q9JKU0-1", "name": "Taste receptor type 2 member 16", "aln": "MVPTQVTIFSIIMYVLESLVIIVQSCTTVAVLFREWMHFQRLSPVEIILISLGISHFCLQWTSMLYNFGTYSRPVLLFWKVSVVWEFMNVLTFWLTSLLAVLYCVKVSSFSHPVFLWLRLKILKLVLWLLLGALIASCLSIIPSVVKYHIQMELLTLDHLPKNSSLILRLQMFEWYFSNPFKMIGFGVPFLVFLISIILLTVSLVQHWGQMKHYSS--SSSSLRAQCTVLKSLATFFIFFTSYFLTIVVSFIGTVFDKKSWFWVCEAVIYGLVCIHFTSLMMSNPTLKKALRLQFWSPESS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59529-1", "uniprot_id": "T2R16_MOUSE", "id": "P59529-1", "name": "Taste receptor type 2 member 16", "aln": "MVPTQVTIFSIIMYVLESLVIIVQSCTTVAVLFREWMHFQRLSPVETILISLGISHFCLQWTSMLYNFGTYSRPVLLFWKVSVVWEFMNILTFWLTSWLAVLYCVKVSSFTHPIFLWLRMKILKLVLWLILGALIASCLSIIPSVVKYHIQMELVTLDNLPKNNSLILRLQQFEWYFSNPLKMIGFGIPFFVFLASIILLTVSLVQHWVQMKHYSS--SNSSLKAQFTVLKSLATFFTFFTSYFLTIVISFIGTVFDKKSWFWVCEAVIYGLVCIHFTSLMMSNPALKKALKLQFWSPEPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYV7-1", "uniprot_id": "T2R16_HUMAN", "id": "Q9NYV7-1", "name": "Taste receptor type 2 member 16", "aln": "MIPIQLTVFFMIIYVLESLTIIVQSSLIVAVLGREWLQVRRLMPVDMILISLGISRFCLQWASMLNNFCSYFNLNYVLCNLTITWEFFNILTFWLNSLLTVFYCIKVSSFTHHIFLWLRWRILRLFPWILLGSLMITCVTIIPSAIGNYIQIQLLTMEHLPRNSTVTDKLENFHQYQFQ-AHTVALVIPFILFLASTIFLMASLTK---QIQHHSTGHCNPSMKARFTALRSLAVLFIVFTSYFLTILITIIGTLFDKRCWLWVWEAFVYAFILMHSTSLMLSSPTLKRILKGKC------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* *:*:* :*:******.*****. **** ***::.:** **: ********:*****:*** ** :* . :: ::::.***:*:*****.* *:*:**:*****:* :***** :**:*. *::**:*: :*::****.: :**::*:*:::**:*.:: :*: *. * : : :.: :**::** * *:* .**.: *::*:*: ...*::*: *.*:***.:* .********::::***:***:.*:** **.:*.:: :* ****:*.*:**: *: : ", "identical_positions": 144, "similar_positions": 104, "identity": "47.84%" }, { "cls_id": "homologset.agr.RGD:620736", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKT9-1", "uniprot_id": "TR107_RAT", "id": "Q9JKT9-1", "name": "Taste receptor type 2 member 107", "aln": "MLSAAEGILLCVVTSEAVLGVLGDTFIALANCMEYAKNKKLSKIGFILIGLAISRIGVVWIIILQGYMQVFFPHILTFGNITEYITYIWVFLNHLSVWFATNLNILYFLKIANFSNSVFLWLKSRVRVVFI-------FLSGCLLTSWLLCFPQFSKMLNNSKMYWGNTSWLQQQKNVFLINQSLTNLGIFFFIIVSLITCFL----LIVFLWRHIRQMHSDGSGLRDLNTEAHVKAMRVLISFAVLFI---LHFVGLSIQVLCFFLPQNNLLFITGLIATCLYPCGHSIILILGNKQLKQASLKALQHLTCCETKRNLSVT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7M725-1", "uniprot_id": "TR107_MOUSE", "id": "Q7M725-1", "name": "Taste receptor type 2 member 107", "aln": "MLNSAEGILLCVVTSEAVLGVLGDTYIALFNCMDYAKNKKLSKIGFILIGLAISRIGVVWIIILQGYIQVFFPHMLTSGNITEYITYIWVFLNHLSVWFVTNLNILYFLKIANFSNSVFLWLKRRVNAVFI-------FLSGCLLTSWLLCFPQMTKILQNSKMHQRNTSWVHQRKNYFLINQSVTNLGIFFFIIVSLITCFL----LIVFLWRHVRQMHSDVSGFRDHSTKVHVKAMKFLISFMVFFI---LHFVGLSIEVLCFILPQNKLLFITGLTATCLYPCGHSIIVILGNKQLKQASLKALQQLKCCETKGNFRVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYW0-1", "uniprot_id": "T2R10_HUMAN", "id": "Q9NYW0-1", "name": "Taste receptor type 2 member 10", "aln": "MLRVVEGIFIFVVVSESVFGVLGNGFIGLVNCIDCAKN-KLSTIGFILTGLAISRIFLIWIIITDGFIQIFSPNIYASGNLIEYISYFWVIGNQSSMWFATSLSIFYFLKIANFSNYIFLWLKSRTNMVLP-------FMIVFLLISSLLNFAYIAKILNDYKTKNDTVWDLNMYKSEYFIKQILLNLGVIFFFTLSLITCIF----LIISLWRHNRQMQSNVTGLRDSNTEAHVKAMKVLISFIILFI---LYFIGMAIEISCFTVRENKLLLMFGMTTTAIYPWGHSFILILGNSKLKQASLRVLQQLKCCEKRKNLRVT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58WW8-1", "uniprot_id": "Q58WW8_DANRE", "id": "Q58WW8-1", "name": "Taste receptor type 2", "aln": "---MEPWLYALISSPLCLIGMVFNLLFFFCLMRPVSGVTLRNPLRFLLIVVLVN-STFQYLVIAVTIIMLLFDYIFWLETVTRALIYQFFCGN---FLCNAWISIFYYISIVPQHHAIFIWIKRNIKAILYGGFILNQIVLTFAISTGAVTYFFLGPVPVNFTALELNSTALAQTLEADMFLFHVANFSYLLYCTCPLVTLIVSWGKTFFYLRGHMKKMGQSGESFSQPQQKSQMRVTVTGMVQAALFLPSSLWTVAAALLYITGLFEEVDPSRFITMTFCSLSSLGNLLCFGFSQSVFRRGIVSVIKKLKG----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .::*:: : : : : . : *:* : :. . :::* : :: : .: . : * :. * . : :.*:*::.*. : :*:*:* . . :: :: : : : : : : : . . : . :: : *:. ::: .*:* :. :. * * ::* .. .: : . : :::. : :*: * :. :: . : . : : .: . *: : . :.:. :::. : .:::*. ", "identical_positions": 22, "similar_positions": 121, "identity": "6.83%" }, { "cls_id": "homologset.agr.RGD:620737", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKT8-1", "uniprot_id": "TR114_RAT", "id": "Q9JKT8-1", "name": "Taste receptor type 2 member 114", "aln": "MLGAMEGVLLSVATSEALLGIVGNTFIALVNCMDCTRNKNLYNIGFILTGLAISRICLVWILITEAYIKIFSPQLLSPINIIELISYLWIITSQLNVWFATSLSIFYFLKIANFSHHIFLWLKRRINIVFAFLIGCLLMSWLFSFPVVVKMVKDKKMLYINSSWQIHMKKSELIINYVFTNGGVFLLFIIMLIVCFLLIISLWRHSKWMQSNESGFRDLNTEVHVKTIKVLLSFIILFILHLIGITINVICLLVPENNLLFVFGLTIAFLYPCCHSLILILANSRLKRCFVRILQQLMCSEEGKEFRNT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7M722-1", "uniprot_id": "TR114_MOUSE", "id": "Q7M722-1", "name": "Taste receptor type 2 member 114", "aln": "MLSTMEGVLLSVSTSEAVLGIVGNTFIALVNCMDYNRNKKLSNIGFILTGLAISRICLVLILITEAYIKIFYPQLLSPVNIIELISYLWIIICQLNVWFATSLSIFYFLKIANFSHYIFVWLKRRIDLVFFFLIGCLLISWLFSFPVVAKMVKDNKMLYINTSWQIHMKKSELIINYVFTNGGVFLFFMIMLIVCFLLIISLWRHRRQMESNKLGFRDLNTEVHVRTIKVLLSFIILFILHFMGITINVICLLIPESNLLFMFGLTTAFIYPGCHSLILILANSRLKQCSVMILQLLKCCENGKELRDT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYW0-1", "uniprot_id": "T2R10_HUMAN", "id": "Q9NYW0-1", "name": "Taste receptor type 2 member 10", "aln": "MLRVVEGIFIFVVVSESVFGVLGNGFIGLVNCIDCAKN-KLSTIGFILTGLAISRIFLIWIIITDGFIQIFSPNIYASGNLIEYISYFWVIGNQSSMWFATSLSIFYFLKIANFSNYIFLWLKSRTNMVLPFMIVFLLISSLLNFAYIAKILNDYKTKN-DTVWDLNMYKSEYFIKQILLNLGVIFFFTLSLITCIFLIISLWRHNRQMQSNVTGLRDSNTEAHVKAMKVLISFIILFILYFIGMAIEISCFTVRENKLLLMFGMTTTAIYPWGHSFILILGNSKLKQASLRVLQQLKCCEKRKNLRVT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .:**::: * .**:::*::** **.****:* :* :* .************* *: *:**:.:*:** *:: :. *:** ***:*:* * .:******************::**:*** * ::*: *:* **:* *:.*. :.*:::* * :: *:::* *** :*: :: * **:::* : **.*::******** : *:** *:** ***.**:::***:********:::*::*:: *: : *.:**::**:* : :** **:****.**:**:. : :** * *.*: *::* *", "identical_positions": 156, "similar_positions": 98, "identity": "50.49%" }, { "cls_id": "homologset.agr.RGD:620738", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKT7-1", "uniprot_id": "T2R13_RAT", "id": "Q9JKT7-1", "name": "Taste receptor type 2 member 13", "aln": "MGSSLYDILTIVMIAEFIFGNVTNGFIVLTNCIAWLSKRTLSFIGWIQLFLAISRVVLIWEMLLAWLKYMKYSFSYLAGTELRVMMLTWVVSNHFSLWLATILSIFYLLKIASFSRPVFLYLKWRVKKVLLLILLGNLIFLMFNILQ-------INTHIEDWMDQYKRNITWDSRVNEFVGFSNLVLLEMIMFSVTPFTVALVSFILLIFSLWKHLQKMHLSSRGERDP--STKAHVNALRIMVSFLLLYATYFISFFISLIPMAHKKGLDLMFSLTVGLFYPSSHSFILILGHSN--LRHSSCLVITYLRCKEKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7M720-1", "uniprot_id": "T2R13_MOUSE", "id": "Q7M720-1", "name": "Taste receptor type 2 member 13", "aln": "MGSNVYGILTMVMIAEFVFGNMSNGFIVLINCIDWVRKGTLSSIGWILLFLAISRMVLIWEMLITWIKYMKYSFSFVTGTELRGIMFTWVISNHFSLWLATILSIFYLLKIASFSKPVFLYLKWREKKVLLIVLLGNLIFLMLNILQ-------INKHIEHWMYQYERNITWSSRVSDFAGFSNLVLLEMIVFSVTPFTVALVSFILLIFSLWKHLQKMHLNSRGERDP--STKAHVNALRIMVSFLLLYATYFISFFLSLIPMAHKTRLGLMFSITVGLFYPSSHSFILILGHSN--LRQASLWVMTYLKCGQKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYV9-1", "uniprot_id": "T2R13_HUMAN", "id": "Q9NYV9-1", "name": "Taste receptor type 2 member 13", "aln": "MESALPSIFTLVIIAEFIIGNLSNGFIVLINCIDWVSKRELSSVDKLLIILAISRIGLIWEILVSWFLALHYLAIFVSGTGLRIMIFSWIVSNHFNLWLATIFSIFYLLKIASFSSPAFLYLKWRVNKVILMILLGTLVFLFLNLIQ-------INMHIKDWLDRYERNTTWNFSMSDFETFSVSVKFTMTMFSLTPFTVAFISFLLLIFSLQKHLQKMQLNYKGHRDP--RTKVHTNALKIVISFLLFYASFFLCVLISWISELYQNTVIYMLCETIGVFSPSSHSFLLILGNAK--LRQAFLLVAAKVWAKR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58WW8-1", "uniprot_id": "Q58WW8_DANRE", "id": "Q58WW8-1", "name": "Taste receptor type 2", "aln": "---MEPWLYALISSPLCLIGMVFN-LLFFFCLMRPVSGVTLRNPLRFLLIVVLVNSTFQYLVIAVTIIMLLFDYIFWLETVTRALIYQFFCG---NFLCNAWISIFYYISIVPQHHAIFIWIKRNIKAILYGGFILNQIVLTFAISTGAVTYFFLGPVPVNFTALELNSTALAQTLEADMFLFHVANFSYLLYCTCPLVTLIVSWGKTFFYLRGHMKKMGQSGESFSQPQQKSQMRVTVTGMVQAALFLPSSLWTVAAALLYITGLFEEVDPSRFITMTFCSLSSLGNLLCFGFSQSVFRRGIVSVIKKLKG----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: . ::* : * ::.: : : * : :::.: . : : :: : : : : * * :: :. . .: : :**** :.*.. . *:::* . : :: :: . :.* : : :. .: .. : :. : . : ::. *:.. ::*: :* * *::** . .. :* :: :... :: : *:: :: : : *: . ** . :* :* :: :*:. * : ", "identical_positions": 29, "similar_positions": 111, "identity": "9.18%" }, { "cls_id": "homologset.agr.RGD:620739", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M798-1", "uniprot_id": "F1M798_RAT", "id": "F1M798-1", "name": "Metalloendopeptidase", "aln": "-------MPGVARPPLPLLSLP-LLLLLLLPRAGRP----------------------------------------LDLADYTYDLGE---EDAPELLNYKD----------------------------------------------PCKAAAFLGDIALDEED--------------------------------------------------------------------------------------------LRAFRVQQAAVLRQQTAQRSSIKAA--GNSSALG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RQSTSGQPQRGSRGRWRS-------------------------RPRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDS--YIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNG------------------------YSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKDN--GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAA-CGGFL--TKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEG----NDVCKYDFVEVRSGLTAD-SKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYD----STAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTS-----------------------TKFQDTLHSRK----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98063-1", "uniprot_id": "BMP1_MOUSE", "id": "P98063-1", "name": "Bone morphogenetic protein 1", "aln": "-------MPGVARPPLPLLSLPLLLLLLLLPRAGRP----------------------------------------LDLADYTYDLGE---EDAPELLNYKD----------------------------------------------PCKAAAFLGDIALDEED--------------------------------------------------------------------------------------------LRAFQVQQAAVLRQQTARRPSIKAA--GNSSALG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQGTSGQPQRESRGRWRG-------------------------RPRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDS--YIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNG------------------------YSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKDN--GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAA-CGGFL--TKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEG----NDVCKYDFVEVRSGLTAD-SKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYIELFDGYD----STAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTS-----------------------TKFQDTLHSRK----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13497-1", "uniprot_id": "BMP1_HUMAN", "id": "P13497-1", "name": "Bone morphogenetic protein 1", "aln": "-------MPGVAR-------LPLLLGLLLLPRPGRP----------------------------------------LDLADYTYDLAE---EDDSEPLNYKD----------------------------------------------PCKAAAFLGDIALDEED--------------------------------------------------------------------------------------------LRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CQSTNGQPQRGACGRWRG-------------------------RSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDS--YIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNG------------------------YSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKDY--GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAA-CGGFL--TKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEG----NDVCKYDFVEVRSGLTAD-SKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYD----STAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS-----------------------TKFQDTLHSRK----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1Y0-1", "uniprot_id": "A0A8M2B1Y0_DANRE", "id": "A0A8M2B1Y0-1", "name": "Metalloendopeptidase", "aln": "-------MN-----------SPWTRVLVLIFC--------------------------------------------LLTVDTIYQTGP---GESDE-VDYKD----------------------------------------------PCKAVAFLGDIALDEED--------------------------------------------------------------------------------------------LRFLKAHYMHATENESSGSS--------KPDSVN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSSANRNAKDEPVLANQS-------------------------ILRRRRAATARPERVWPNGIIPYIISGNFTGSQRAIFKQAMRHWEKHTCVTFVERSVEES--YIVFTLRPCGCCSFVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVDIFRENIQPGQEYNFIKMEPDDVDSLGEVYDFDSIMHYARNTFSRGIYLDTMLPKYDVDGVRPPIGQRTRLSKGDIAQARKLYRCPRCGESLQDSAGNFSSPGFPNG------------------------YAAYLHCIWRISVTPGEKIVLNFTSMDLYRSNLCWYDYVEVRDGYGRSAPLKGRICGDQLPEAIVSTDSELWIEFRSTSNWVG-KGFSAVYEAICGGEVRRDS--GQIESPNYPDDYRPNKACIWKIVVPEGFHVGLVFQSFEIEKHDNCAYDYLEVRDGDSESSPLLGRFCGYEKPDDFKSSSNQLWMKFVSDGSVNKAGFAANFFKEIDECSRPDNAHCEQRCINTLGSFHCACDPGFELAPDRRSCAAAACGGFI--SKLNGSFTSPGWPQEYPPNKNCVWQLIAPVQYRITLLFDAFEMEG----NDVCKYDYVEVHSGLSAD-GKLHGKFCGTEKPEAITSQLNSMSVEFKSDNTVSKRGFKAQFFSDMDECSRENGGCQHECVNTFGSYSCQCRSGFVLHSNKHDCKEVGCDQAITSVSGLITSPNWPDKYPSKKACTWTLSTTPGHRIKLAFEEIDMEAHQECAYDHLEIYDGQNGRATSVGRFCGSKKPSPVISSSNTMFLRFFSDNSVQKRGFKASHSAECGGSLKAEIKTKDLYSHAQFGDNNYPGASDCQWVISAEKGYGVELIFHTFEIEEEADCGYDYVELFDGGD----VKAPRLGRYCGSGPPEEIYSAGDAIVIKFHSDDTINKKGFHVRYTS-----------------------TKFQDTLHTSK----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC47-1", "uniprot_id": "TOK_DROME", "id": "Q9VC47-1", "name": "Protein tolkin", "aln": "MRRRRGTPLGVSWTNCVLLLATGLLVVLISVHAKNPRPHRGLPAPAPAPVPASVDQVATENAHRREPTVDGSVLQRLSGSDRAVDEDEDVDEDEDEGLKHQHLEHRQQFDAYLGTIRRLRRPYRSKYTIEQLMRLHVTPKVSGDIDMDPCKAGGFMGDIALPEGDSGPVVAHTPIDDEEQERQEVEQLLADSPSPVHDPPSVSGAANSGPTKFNATFQLDLEKLKQEVYHEGLQVEEEGLTDIIRKKTKLPSSGPVNLKAGQSQSQSQSANEPVKPGSESPSDYAQASSYKNEVLPPSEQRIHTDKPARLTLAEIGPKFSNKTQSLHRNVDTRKIQSDNKDIEDDSGNNFVAERRPSQIVPTSLPEQRSTPAHVYSNAGGNGMQLDDEVDFLHSRGVVRRRHRRGPKQRRSNQHLEHEVKLQRLREELSRPVIEAHHHQSHHQKQAQHRQHHQSHHRKKHRRQQQHHRRRGQSTTQYVNHSPPGFNQSQQAQQQSVPEMDLLKAETSKDEEPLRHRVARAVTAKKERIWDYGVIPYEIDGNFSGIHKALFKLAMRHWENSTCIKFVERDPEIHPNYIVFTVRSCGCCSFVGKRGNGPQAISIGRNCDKFGIVVHELGHVVGFWHEHTRPDREKHVVIEHNNIMKGQDYNFNMLSPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRKRPEIGQRLRLSQGDIAQANLLYKCPKCGRTFQESSGIFASPSHYTAG---------------------ALSNETEHCEWRITATYGERVELKLENMNIFKSNNCETDYLEIRDGYFEKSPLIGRFCGKVDKEVIRTESSRMLLTYVNTHRIEGFRGFKAEFDVVCGGELSVDDAVGRLESPNYPLDYLPNKECVWKITVPESYQVALKFQSFEVENHDSCVYDYVEVRDGPGQDAPLIGVFCGYKPPPNMKSSGNSMYVKFVSDTSVQKAGFSAVFMKEVDECETQNHG-CEHECINTLGGYECSCRIGFELHSDKKHCEDA-CGGVI--EYPNGTITSPSFPEMYPLLKECIWEIVAPPKHRISLNFTHFDLEGTAHQQSDCGYDSVTVYSKLGENRLKRIGTFCGSSIPPTATSESNALRLEFHSDKSIQRSGFAAVFFTDIDECAVNNGGCQHECRNTIGSYICMCHNGYSMHENGHDCKEGECKYEISAPFGTIFSPNYPDSYPPNADCVWHFITTPGHRIKLIFNEFDVESHQECTYDNVAVYDGESESSSVLGRFCGDKIPFPISSTSNQMYMVLKTDKNKQKNGFTASHSTACGGYLRATSQVQQFYSHARFGNQDYDDGMDCEWTIAAPDNSYVQLIFLTFDIESSENCTFDYVQVFSDIDDVYGQYGPMYGQYCGNVLPQDINSMTHSLLVRFKTDGSVPMKGFSASYVAVPNSGEYDHSDEDVENSYSSEMVTPFPGSLKSIYIEDTQEETDEYSDFSGNQLVFNGQYRGRYSLPKRYYSGKA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25723-1", "uniprot_id": "TLD_DROME", "id": "P25723-1", "name": "Dorsal-ventral patterning protein tolloid", "aln": "-------MKGMRLMPMKMKAKLVVLSVGALWMMM------------------------------------------FFLVDYAEGRRLSQLPESECDFDFKE---------------------------------------------QPEDFFGILDSSLVPPKEPKDD---------------------------------------------------------------------------------------IYQLKTTRQHSGRRRKQSHKSQNKAALRLPPPFLWT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDAVDVLQHSHSPTLNGQP-------------------------IQRRRRAVTVRKERTWDYGVIPYEIDTIFSGAHKALFKQAMRHWENFTCIKFVERDPNLHANYIYFTVKNCGCCSFLGKNGNGRQPISIGRNCEKFGIIIHELGHTIGFHHEHARGDRDKHIVINKGNIMRGQEYNFDVLSPEEVDLPLLPYDLNSIMHYAKNSFSKSPYLDTITPIGIPPGTHLELGQRKRLSRGDIVQANLLYKCASCGRTYQQNSGHIVSPHFIYSGNGVLSEFEGSGDAGEDPSAESEFDASLTNCEWRITATNGEKVILHLQQLHLMSSDDCTQDYLEIRDGYWHKSPLVRRICGNVSGEVITTQTSRMLLNYVNRNAAKGYRGFKARFEVVCGGDLKLTKD-QSIDSPNYPMDYMPDKECVWRITAPDNHQVALKFQSFELEKHDGCAYDFVEIRDGNHSDSRLIGRFCGDKLPPNIKTRSNQMYIRFVSDSSVQKLGFSAALMLDVDECKFTDHG-CQHLCINTLGSYQCGCRAGYELQANGKTCEDA-CGGVVDATKSNGSLYSPSYPDVYPNSKQCVWEVVAPPNHAVFLNFSHFDLEGTRFHYTKCNYDYLIIYSKMRDNRLKKIGIYCGHELPPVVNSEQSILRLEFYSDRTVQRSGFVAKFVIDVDECSMNNGGCQHRCRNTFGSYQCSCRNGYTLAENGHNCTETRCKFEITTSYGVLQSPNYPEDYPRNIYCYWHFQTVLGHRIQLTFHDFEVESHQECIYDYVAIYDGRSENSSTLGIYCGGREPYAVIASTNEMFMVLATDAGLQRKGFKATFVSECGGYLRATNHSQTFYSHPRYGSRPYKRNMYCDWRIQADPESSVKIRFLHFEIEYSERCDYDYLEITEEGY----SMNTIHGRFCGKHKPPIIISNSDTLLLRFQTDESNSLRGFAISFMAVDPPEDSVG--------EDFDAVTPFPGYLKSMYSS----ETGSDHLLPPSRLI--------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : ...:. * . .::.. : : : : .. . . . : * **.* : ** * *:**: *. *:* ::*:*: ******: **:.*:** : ** ** : *****::*:.*.* *.****:**:****::*****.:** ***:* **:.*: * : ** **:*** :. ::*: ** :******:*:**:. :***: * : :*** ***:***.**. **:*. **.: *:.:* : ** . . :* ***:.* **:: *:: .:.: * * **:*:***: ..:** *:** * * : *.: : : . * :** * ::.:***:: ::***** ** *.* *:*:* ..:..:*.* *****:*.**.*.**::*:*** ..: *:* :** : * ::*: .. ::::**** *::* **:. :: ::***. :.. *:: *:****.:.*.* *:** .: : * * ***.: **:: **.:*. ** *:*:*:::** :: : * * *: ** * ** : : * : : * * :** . * . .*: . : :** **.::.: ** * *. * ***: :*****: * **:*** * *:.*: : .* *:*.* *. ::: * : ***:*:.** : * * : :. ***::* * ::::*:: ** ** : ::**.. :. :* :**.: * .: :: . *:: : :* . *:.** *:. : *** ::* : : :***.::*.. * *:* * * *:: * *::* . * :**::: . . *::**. * : * .:::::*::* : :** : : * * . *:: ", "identical_positions": 323, "similar_positions": 305, "identity": "21.69%" }, { "cls_id": "homologset.agr.RGD:62074", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18331-1", "uniprot_id": "INHBA_RAT", "id": "P18331-1", "name": "Inhibin beta A chain", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPLLWLRGFLLASCWII-VRSSPTPGSEGHGAAPDCPSCALATLPKDGPN------------------------------SQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVG------KVGENGYVEIEDDIGRRAEMN----------ELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVER------------AEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDMGDEAEEMGLKGERS-----------------------------------------------------------------------------------------------ELLLSEKVVDARKSTWHIFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEVDGDGKKKDGSDG----------------------------------------------------------------------------------------GLEEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVN-ICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04998-1", "uniprot_id": "INHBA_MOUSE", "id": "Q04998-1", "name": "Inhibin beta A chain", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPLLWLRGFLLASCWII-VRSSPTPGSEGHGSAPDCPSCALATLPKDGPN------------------------------SQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVG------KVGENGYVEIEDDIGRRAEMN----------ELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVER------------AEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGDEAEEMGLKGERS-----------------------------------------------------------------------------------------------ELLLSEKVVDARKSTWHIFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEVDGDGKKKDGSDG----------------------------------------------------------------------------------------GLEEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVN-ICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08476-1", "uniprot_id": "INHBA_HUMAN", "id": "P08476-1", "name": "Inhibin beta A chain", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPLLWLRGFLLASCWII-VRSSPTPGSEGHSAAPDCPSCALAALPKDVPN------------------------------SQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVG------KVGENGYVEIEDDIGRRAEMN----------ELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVER------------AEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERS-----------------------------------------------------------------------------------------------ELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGA--------------------------------------------------------------------------------------GADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVN-ICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O61643-1", "uniprot_id": "INHB_DROME", "id": "O61643-1", "name": "Inhibin beta chain", "aln": "MRFAFDSNHSQSGAPFKGSRCFFNCQCICCRQGCCVVVVKCCCCFNLNCCNSLGSRKSFPQPAAMRKKVADLEVLRVSRFVAVILVLARWVTAVATLLTSCILLDIFSVPGQSGVADRSQASSRTVHVSVPTTPNETPSSTSETKLKLLYGYTSYDINNDQQVKSNNLCRVLCKSRNRKRQRRRRRRRNHRRRRHRYTKRLHHLMQDNMSGFEQRLNFSDAKCQSLETNYGTNYDLVQGGKLFSQSERSLLVSPLREIEAPWPAIHGSMRNCSKIKRNRANLIWLLIGLVWFEVKLINCNGIS-SSNYYASNLESHKGCTLCHESGKPNIYTDKDNPHTDYNIYNKYHSNNNFNKKTNQPHNNIAPSDEVRLESIKRQILTKLGLSHKPNVSHPLPKQFIWETIYRVDGGRMIPNNAFGSSGKNLDQKTIKLRAFASPGSHLFNGRGGRTDQRSERDPSHHKYRSPFDFTFNISKNNVYGKVLRNRSLERIDKKNSFLNGWTENRQLKINSQIASMPIELKSHHNSSPKELKSGAVRKVNGINGTQMNENALKKSTYPIDINHSIDNKTHTGKNGEMSHNDYEYFNDYSVQTHDKNRYHEGRSSIGYQPAIHNIEYENQKGHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLHLFQTSKLRGNSSDYLSTNPNRPFLVLHTESS--RTRRVRRRAVDCGGALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFR-TPDTFQTFHAHFIEEYRKMG--LMNGMRPCCAPIKFSSMSLIYYGD-DGIIKRDLPKMVVDECGCP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQG9-1", "uniprot_id": "INHBA_DROME", "id": "Q9VQG9-1", "name": "Protein dawdle", "aln": "-------------------------------------MAKYFIALVLLVCLALENRNVYNRLHARSHPSSRGDILRP--------------------------------------HPKHQPHPHVQHTSQQLQQQHHIRQQRSRQLKHLEPDPTSEEDDVPITKREYYARLRRHVIHKRQHLLQQELSYNHPGSHSEQLKVPRLWQHLMEQEEK-----AHRHVSPPVELPIMYGDAPEESSLSSDDHFDDLSPLDFVRNELMAED---------QQNQEKDLDLDLDLDQQPETPIEPELPLGERNITISVKSSAGGCPKCESNRQVEHITEEQL-------------------------------THLRIEFVKQQILEKLRLKESPKVSAVELPKPIFDGMTLSHPD---------DSTKNKELDDYYARTSKK---------FILLNREEVECNRARDGKSNPSMCFTFKIDDADAEGFDVS----------TAVLWLFKN--KQNRTDTASVNSTSAQQTIVVSEVEVDQQKDSKYLSAAKT--------------------------------------------------------------------------------------------------IAIQSVNVQD-EWMKIDIEWPIKHWISGHELSHLIQITCGGCDVSDMEEIIS-----------------------------------------------------------------------------------------------------------------VDKDYRPFIVIDMQNR--RRKSRQKRSINCSSGMT-ECCREHLYISFRDIGWSNWILKPEGYNAYFCRGSCSSVASVTQAA--SHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQLVVMDSSNTATVKTLPNMVVESCGCR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . . .. ... * . .: :* :*::** * *.. *.*: : : : . . .. . *: . :: . .. : : * :. :. . . * . * * : ::. .:. . . :.. : :: ..: : : .. :: . :* . . : ***:::. .. : : ::*.::*.. :. **:: :::**: :**.:**: * ** * :*.*.*.. * : :.*: .:: * : .**.. : .:.:: .. : : : :*:*:.*** ", "identical_positions": 46, "similar_positions": 131, "identity": "4.83%" }, { "cls_id": "homologset.agr.RGD:620741", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKT5-1", "uniprot_id": "TR105_RAT", "id": "Q9JKT5-1", "name": "Taste receptor type 2 member 105", "aln": "MLSAAEGILLSIATVEAGLGVLGNTFIALVNCMDWAKNKKLSKIGFLLFGLATSRIFIVWILILDAYAKLFFPGKYLSKSLTEIISCIWMTVNHMTVWFATSLSIFYFLKIANFSHYIFLWLKRRTDKVFA--FLLWCLLISWAISFSFTVKVMK-SNPKNHGNRTSGTHWEKREFTSNYVLINIGVISLLIMTLTACFLLIISLWK-------HSRQMQSNVSGFRDLNTEAHVKAIKFLISFIILFI---LYFIGVAVEIICMFIPENKLLFIFGLTTASVYPCCHSVILILTNSQLKQAFVKVLEGLKFSENGKDLRAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKT4-1", "uniprot_id": "TR105_MOUSE", "id": "Q9JKT4-1", "name": "Taste receptor type 2 member 105", "aln": "MLSAAEGILLSIATVEAGLGVLGNTFIALVNCMDWAKNNKLSMTGFLLIGLATSRIFIVWLLTLDAYAKLFYPSKYFSSSLIEIISYIWMTVNHLTVWFATSLSIFYFLKIANFSDCVFLWLKRRTDKAFV--FLLGCLLTSWVISFSFVVKVMK-DGKVNHRNRTSEMYWEKRQFTINYVFLNIGVISLFMMTLTACFLLIMSLWR-------HSRQMQSGVSGFRDLNTEAHVKAIKFLISFIILFV---LYFIGVSIEIICIFIPENKLLFIFGFTTASIYPCCHSFILILSNSQLKQAFVKVLQGLKFF---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NYW0-1", "uniprot_id": "T2R10_HUMAN", "id": "Q9NYW0-1", "name": "Taste receptor type 2 member 10", "aln": "MLRVVEGIFIFVVVSESVFGVLGNGFIGLVNCIDCAKN-KLSTIGFILTGLAISRIFLIWIIITDGFIQIFSPNIYASGNLIEYISYFWVIGNQSSMWFATSLSIFYFLKIANFSNYIFLWLKSRTNMVLP--FMIVFLLISSLLNFAYIAKILN-DYKTKN-DTVWDLNMYKSEYFIKQILLNLGVIFFFTLSLITCIFLIISLWR-------HNRQMQSNVTGLRDSNTEAHVKAMKVLISFIILFI---LYFIGMAIEISCFTVRENKLLLMFGMTTTAIYPWGHSFILILGNSKLKQASLRVLQQLKCCEKRKNLRVT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58WW8-1", "uniprot_id": "Q58WW8_DANRE", "id": "Q58WW8-1", "name": "Taste receptor type 2", "aln": "---MEPWLYALISSPLCLIGMVFNLLFFFCLMRPVSGVTLRNPLRFLLIVVLVNSTFQYLVIAVT-IIMLLFDYIFWLETVTRALIYQFFCGN---FLCNAWISIFYYISIVPQHHAIFIWIKRNIKAILYGGFILNQIVLTFAISTGAVTYFFLGPVPVNFTALELNSTALAQTLEADMFLFHVANFSYLLYCTCPLVTLIVSWGKTFFYLRGHMKKMGQSGESFSQPQQKSQMRVTVTGMVQAALFLPSSLWTVAAALLYITGLFEEVDPSRFITMTFCSLSSLGNLLCFGFSQSVFRRGIVSVIKKLKG----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :*:: * :: : : . *:* : . * :: :: : .: . : :. * . : :****::.*. . :*:*:* . . : *:: :: : :. . . .: : . .::::. : : . . **:* : * ::* .. .: : : :::::. : **: *: :. :: . * . :: :* :: . : . : : :* :::. : *:: ** ", "identical_positions": 29, "similar_positions": 105, "identity": "9.01%" }, { "cls_id": "homologset.agr.RGD:620742", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PM9-1", "uniprot_id": "UCK2_MOUSE", "id": "Q99PM9-1", "name": "Uridine-cytidine kinase 2", "aln": "---MAGDSEQTLQN--HQQ--PNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYHQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELIFKTLKEITEGKTVQIPVYDFVSHSRKEE-TVTIYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNL---VAINLIVQHIQDILNGGLSKRQTNGYLNGYTPSRKRQASESSSRPH---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QYG8-1", "uniprot_id": "UCK2_RAT", "id": "Q9QYG8-1", "name": "Uridine-cytidine kinase 2", "aln": "---MAGDSEQTLQN--HQQ--PNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYHQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELIFKTLKEITEGKTVQIPVYDFVSHSRKEE-TVTIYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNL---VAINLIVQHIQDILNGGLSKRQTNGYLNGYTPSRKRQASESSSRPH---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZX2-1", "uniprot_id": "UCK2_HUMAN", "id": "Q9BZX2-1", "name": "Uridine-cytidine kinase 2", "aln": "---MAGDSEQTLQN--HQQ--PNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEE-TVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNL---VAINLIVQHIQDILNGGPSKRQTNGCLNGYTPSRKRQASESSSRPH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYM0-1", "uniprot_id": "UCK2A_DANRE", "id": "Q7SYM0-1", "name": "Uridine-cytidine kinase 2-A", "aln": "---MAGDSDSKLDN--HAENEHVDWQPFLIGVAGGTASGKSSVCGKIMELLGQNKIDHHQRQVAILSQDSFYRVLTPEQKAKALKGQFNFDHPDAFDNELIVKTLCEIMEGRTVQIPVYDFVTHSRKEE-TVTVYPADVVLFEGILMFYSQEIRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQVLNQYITFVKPAFEEFCLPTKKYADVIIPRGADNL---VAINLIVQHIQDFLNGGLTKR-LNGCLNGHTP-RKRHPSESSSRPH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7ZV79-1", "uniprot_id": "UCK2B_DANRE", "id": "Q7ZV79-1", "name": "Uridine-cytidine kinase 2-B", "aln": "---MAGDSETHLKD--RAENGHAVRQPFLIGVSGGTASGKSSVCEKIMELLGQNKIDRHQRQVVILSQDSFYRELTPEQKAKAVKGQFNFDHPDAFDSELIMKTLRDIIQGKTVHIPVYDFVTHSRKDE-FLTLYPADVVLFEGILMFYSQEIRDLFKMKLFVDTDPDTRLSRRVLRDISERGRELEQVLNQYITFVKPAFEEFCLPTKKYADVIIPRGADNL---VAINLIVQHIQDILNGGFTKR-QNGFQNGHGTPRQRRTSESS-RPH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC99-1", "uniprot_id": "UCK_DROME", "id": "Q9VC99-1", "name": "Uridine-cytidine kinase", "aln": "MQDLRNADTLRLPNGDGAAANDEVKSPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAEKAKAQKGLFNFDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNSLDFENVLVIYPADVVLFEGILVFYFPKIRELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTKKFADVIIPRGADNT---VAIDLIVHHIGEILATTNSAQHSN---------TVRVAASSMKRDH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12084-1", "uniprot_id": "DAS2_YEAST", "id": "Q12084-1", "name": "Putative uridine kinase DAS2", "aln": "------MDRKAVEE-----------KRIVISIGGGHATG-----------VGAIALDLQN------TFKSLYNSIN--IRVINLDNMIEGNIKSYNNNDYDFDNILNLVYEKHAVTSQNDMIQHDYEDP-------IDLIIVCGCYALYDKRINEISQLKVFLDSDADKRLISLIKKKNVGSNEQLAQLITEYMDHLRPEMQQYIEPTRTFADLIIPSTNENLGRAVLVDGIVKAIEDTKSQIEGNNTNNKIRPRLWDFEAETMDLEKDRYYDLS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . ::*.:.** *:* :* :* : : .*:*. :. :. .. :: : . :.: ..: :: : . . * :. . *:::. * :* .:.:: ::*:*:*:*.*.** : :. ..:* ::.:*: .::* :::: **:.:**:*** :* * :: **: * : . * . . * : ", "identical_positions": 37, "similar_positions": 89, "identity": "13.45%" }, { "cls_id": "homologset.agr.RGD:620743", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6W8-1", "uniprot_id": "G3V6W8_RAT", "id": "G3V6W8-1", "name": "Bone morphogenetic protein 7", "aln": "MHVRSLRAAAPHSFVALWAPLFLLR----------SALADFSLDNEVHSSFIHRRLRSQERREMQREILSILGLPHRP---RPHLQGKHNSAPMFMLDLYNAMAVEESG-PDGQGFSYP----------YKAVFSTQGPPLASLQDSHFLTDADMVMSFVNLVEHDKEFFHPRYHHREFRFDLSKIPEGEAVTAAEFRIYKDYIRERFD--NETFQITVYQVLQEHSGRESDLFLLDSRTIWASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLD--GQSINPKLAGLIGRHGP-QNKQPFMVAFFKATEVHLRSIRSTGGKQRSQNRSKTPKNQEALRMASVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPDTVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23359-1", "uniprot_id": "BMP7_MOUSE", "id": "P23359-1", "name": "Bone morphogenetic protein 7", "aln": "MHVRSLRAAAPHSFVALWAPLFLLR----------SALADFSLDNEVHSSFIHRRLRSQERREMQREILSILGLPHRP---RPHLQGKHNSAPMFMLDLYNAMAVEESG-PDGQGFSYP----------YKAVFSTQGPPLASLQDSHFLTDADMVMSFVNLVEHDKEFFHPRYHHREFRFDLSKIPEGEAVTAAEFRIYKDYIRERFD--NETFQITVYQVLQEHSGRESDLFLLDSRTIWASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLD--GQSINPKLAGLIGRHGP-QNKQPFMVAFFKATEVHLRSIRSTGGKQRSQNRSKTPKNQEALRMASVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPDTVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18075-1", "uniprot_id": "BMP7_HUMAN", "id": "P18075-1", "name": "Bone morphogenetic protein 7", "aln": "MHVRSLRAAAPHSFVALWAPLFLLR----------SALADFSLDNEVHSSFIHRRLRSQERREMQREILSILGLPHRP---RPHLQGKHNSAPMFMLDLYNAMAVEEGGGPGGQGFSYP----------YKAVFSTQGPPLASLQDSHFLTDADMVMSFVNLVEHDKEFFHPRYHHREFRFDLSKIPEGEAVTAAEFRIYKDYIRERFD--NETFRISVYQVLQEHLGRESDLFLLDSRTLWASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLD--GQSINPKLAGLIGRHGP-QNKQPFMVAFFKATEVHFRSIRSTGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P27091-1", "uniprot_id": "60A_DROME", "id": "P27091-1", "name": "Protein 60A", "aln": "MSGLRNTSEAVAVLASLGLGMVLLMFVATTPPAVEATQSGIYIDNGKDQTIMHRVLSEDDKLDVSYEILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDYERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHNVDELR-HEHGRRLWFDVSNVPNDNYLVMAELRIYQNANEGKWLTANREFTITVYAIGTGTLG-QHTMEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVD-DEFQPFMIGFFRGPELIKATAHSSHHRSK-RSASHPRKRKKSVSPNNVPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGCH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54631-1", "uniprot_id": "SCW_DROME", "id": "P54631-1", "name": "Protein screw", "aln": "-------MLNVFFLTSLFYAA--------------SATTYVTTNNHIEMPIYQKRP-----LSEQMEMIDILDLGDRPR--RQAEPNLHNSASKFLLEVYNEISEDQEPKEVLHQRHKR---------------SLDDDILISNEDRQEIASCNSILTFSSRLKP---EQLDNELDMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRR---ANFTVSVYRKLDNRQD--FSYRILGSVNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRNELRISIGD---SQLSTFAAGLVTPQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAG----GGSPPPPPPPPVDLYRPPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQP-HLPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGCH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:* :: : . :* . .: :: . . *::.:*.: .** . ::**. *:*::*: :: :: . . : : : * : : ..: :::* . . . .: *: ..:* . :. * :***:: * ::** . *.* . .. *** :::* . *: : : : : .:. **: : . :**::.:*...*: : :. : : : . . ::*: : :.*::* ::*:***: : *::* * * ***.: ************:*: :* :*****.** *.*:.:* . :.. : *.**:: :.: ****", "identical_positions": 80, "similar_positions": 138, "identity": "17.43%" }, { "cls_id": "homologset.agr.RGD:620744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKU3-1", "uniprot_id": "IF172_RAT", "id": "Q9JKU3-1", "name": "Intraflagellar transport protein 172 homolog", "aln": "MQLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADMKYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQWPAEYIIVFGLAEGKVRLANTKTNKSSTIYGTDSYVVALTTNCSGKGILSGHADGTIVRYFFDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRRIVAYGKEGHVLQTFDYSRDPQEREFTTAAASPGGQSVVLGSYDRLRVFNWSPRRSIWEEAKPKEIANLYTVTALAWKRDGSRLCAGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQLIVKNLS-SGTRVVLKSHYGYEVEEVKILGKERYLVAHTSDTLLLGDLNTNRLSEIPWQGSGGNEKYFFENENVCMIFNAGELTLVEYGSNDSLGSVRTEFMNPHLISVRINERCQRGMEDNKKLAYLVDIKTIAIVDLIGGYNIGTISHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYVQWVPGSDVLVAQNRNSLCVWYNIEAPERVTMSSIRGDVVGLERGGGKTEVMVTEGVTTVAYTLDEGLIEFGTAIDDGNYTRATAFLETLEMTPETEAMWKTLSKLALEARQLHTAERCFSALGHVAKARFLHETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMDMYQELHRWDECIAVAEAKGHPALEKLRRDYYQRLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTELVEHITTALIKGELYERAGDLFEKIRNPQRALECYCKGNAFMKAVELARLAFPVEVVRLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDR-NTASKYYPRVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVEEPDLAITMFKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKELETEGRLQEAEYHYLEAQEWKATVNMYRSSGLWEEAYRVAKAHGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAIDHAADNCSFEFAFELSRLALKHKTPEIHLRYAMYLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPGQLEALQ--------EEYEREATKKGGRGVEGLVEQARQWEQAGEYSRAVDCYLKVRDS--GSSGLMEKCWMKAAELSIKFLPPQRSLEVVRVVGPQLIGIGKHSASAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDP--RYEDYVDQHYKEFLKNQGKVDSLVGVDVVAALDLYVEQGQWDKCIETATKQNYKILHKYVALYATHLIREGGYAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNNAEAYHSWADLRDVLFNLCENLVKS-SEANSAAHEEFEMMLLIAHYYATRSAAQSIKQLETVAARLSVSLLRHTQLLPADKAFYEAGTAAKEVGWENMAFIFFNRFLDLTDAIEEGTLDALDHSDFQDTDIPFEVPLPAKQHVPEAQ--REEVRDWVLTVSMDQRLEQVLPRDERGVYEASLVAASTGVRALPCLITGYPIL-RNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6VH22-1", "uniprot_id": "IF172_MOUSE", "id": "Q6VH22-1", "name": "Intraflagellar transport protein 172 homolog", "aln": "MQLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADMKYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQWPAEYVIVFGLAEGKVRLANTKTNKSSTIYGTESYVVALTTNCSGKGILSGHADGTIVRYFFDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRRIVAYGKEGHVLQTFDYSRDPQEREFTTAAASPGGQSVVLGSYDRLRVFNWSPRRSIWEEAKPKEIANLYTVTALAWKRDGSRLCAGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLS-SGTRVVLKSHYGYEVEEVKILGKERYLVAHTSDTLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLVEYGSNDSLGSVRTEFMNPHLISVRINERCQRGMEDNKKLAYLVDIKTIAIVDLIGGYNIGTISHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYVQWVPGSDVLVAQNRNSLCVWYNIEAPERVTMSSIRGDVVGLERGGGKTEVMVTEGVTTVAYTLDEGLIEFGTAIDDGNYTRATAFLETLEMTPETEAMWKTLSKLALEARQLHTAERCFSALGHVAKARFLHETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMDMYQELHRWEECIAVAEAKGHPALEKLRRDYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTELVEHITTALIKGELYERAGDLFEKIRNPQRALECYCKGNAFMKAVELARLAFPVEVVRLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDR-NTASKYYPRVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVEEPDLAITMFKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRSSGLWEEAYRVAKAHGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEATIDHAADNCSFEFAFELSRLAFKHKAPEIHLKYAMYLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPGQLEALQ--------EEYEREATKKGGRGVEGLVEQARQWEQAGEYSRAVDCYLKVRDS--GSSGLMEKCWMKAAELSIKFLPPQRSLEVVRVVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDP--RYEDYVDQHYKEFLKNQGKVDSLVGVDVVAALDLYVEQGQWDKCIETATKQNYKILHKYVALYATHLIREGGYAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNNAEAYHSWADLRDVLFNLCENLVKS-SEANSAAHEEFEMMLLISHYYATRSAAQSIKQLETVAARLSVSLLRHTQLLPADKAFYEAGTAAKEVGWENMAFIFLNRFLDLTDAIEEGTLDALDHSDFQDTDIPFEVPLPAKQHVPEAQ--REEVRDWVLTVSMDQRLEQVLPRDERGVYEASLVAASTGVRALPCLITGYPIL-RNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UG01-1", "uniprot_id": "IF172_HUMAN", "id": "Q9UG01-1", "name": "Intraflagellar transport protein 172 homolog", "aln": "MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADMKYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQWPAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYFFDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQEREFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSRLCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLS-SGTRVVLKSHYGYEVEEVKILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLVEYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIGTVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVAQNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFGTAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFLHETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHRWDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMKAVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDR-NTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVARTQGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHKTPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEALQ--------EEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDS--GNSGLAEKCWMKAAELSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDP--RYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYKILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAYHSWADLRDVLFNLCENLVKS-SEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARLSVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDFQDTDIPFEVPLPAKQHVPEAE--REEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTGVRALPCLITGYPIL-RNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RHH4-1", "uniprot_id": "IF172_DANRE", "id": "Q5RHH4-1", "name": "Intraflagellar transport protein 172 homolog", "aln": "MQLKYMKTLLTPQDGAAKVTCMAWAPNNAKFAVCTIDRVVILYDEQGEKRDRFTTKPADPKYGKKTYVVKSMAFSPDSTKIAVAQTDNIIFVYKIGEEWGDKKVICNKFIQTSAVTSLVWPSEHAIIFGLAEGKVRQANTKTSKSSTIYGTDSYVVSLTSNVSGKGILSGHADGTVVRYFIDDEGSGESQGKLLTHACPPYALAWGTNSIIVAGCDKKIVAYGKEGNVIQTFDYSRDRAEKEFTVAASSPSGQSIVVGSFDRLRVFNWSPRKGTWDESSPKEIPNLYTITALSWKKDGSRLSVGTLCGGVEMFDCCLRRSIYKNKFEMTYVGLSQVIVRNLS-TGTRVVLKSQYGYEIDEVKVMGKDQYLVAHTSDTLLLGDLVSNKLSEVAWQGSGGNEKFFFENETVCMIFNAGELALVEYGSNDILGSVRTEFMNPHLISVRLNERRQRGVEDNKKLAYLIDIKTIAIVDLVGGYNLGTISHDSKIDWLELNETGRKLLFRDKKLRLHLYDIESSVKSTMLSFCPYVQWVPGSDVVVAQNRGNLCVWYTIDSPERVTMFPLKGDIVDLERSNGKTEVIVNEGVNSISYTLDEGLIEFGTAIDDGDYYRATAFLETLEMSAETEAMWKTLSKLSLEAQQLHIAERCFAALGDVSKARFLNETNKIADAVAKEYDGDGTDHYQVKARLAMLDKNFKLAEMYYMEQNAVDEVMEMYQELHMWDECIAVAEGKGHPELDNLRRSYYSYLMETNQNEKAAEVKENEGDFTGAVNLYLKAGLPAKAAWLAMSKDELLSSQDIVSRITAALIKGEFYERAGDLFERTRNNQRALECYRKGNAFKKAVDLARVAFPAEVVKLEEVWGDYLVQQKQMDAAINHYIEAGRSIKAIEAAIAARQWKKALHILELQED-RTAAKYYLKIAQYYASVQEFEVAERLFVKGDHIKDAIDMYTQAGRWEQAHKLAVKCMTQEDVSVLYVSRAQELEKEGKYKEAERLFTTVDEPDLAITMYKKNKMYDDMIRLVAVHHKDLLQETHIHLAKELEAESRFQEAEYHYLEGQDWKAAVNMYRVNDMWEEAYRIAKTHGGANAHKQVAYLWAKSLGGEAAVKLLNKFGLLETAIDFAADNYTFDFAFELARLSMKQKIPDIHLKNAMFLEDQGKFNEAEIEFIKAGKPKEAVLMHVHNKDWSNAQRVAEAHDPESVADILVSQAKFCFDQKEFQKAEAFLLRAQRPELAIKYYKDAGMWTDAMRICKDYLPSKLSVLQ--------KEYE----SEGNWGVEGMIEQAQEWEQTGEYSRAVDCYLKVKDS--SNLDLLLKCWMKAAELAIKFLSHDKAVDVSQIVGPRLIQLRKYNEAAELYLNLDLIKNAIDAFIEGEEWNKAKRVAKELDP--RLEEYVDKRYKEHLKNQGKVDSLVGVDVVAALDMYAERGQWEKCIDTASKQNFKVLHKYIALYATHLIKEGEVEKVLSLYIQHGVPAYSQNFNIYKRMFQELVNLRDRDCAEAFRMWSDLRDVLLLLCENLTKS-SEANSPAHEEFEQMLLVAHYYATRSAAKGIDQLSSVAAKLSISLLRHTELIPADKAFYEAGLAAKAVGWENMAFIFLNRFLDLADGIDEGTLDALDHTDFQDTDIPFEVPVPSRLHVTVEK--REEIREWVLTVSMDQRVEQVLPKDERGTYEASLVAASTGIRSLPCVITGYPVL-RNKIEFKRPGMAANKDDWNKFLMATKTTHSPECQDVLKFITQWCGGLPSAGYSFH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W040-1", "uniprot_id": "OSM1_DROME", "id": "Q9W040-1", "name": "Intraflagellar transport protein 172 homolog", "aln": "MQLKYLRTLLEGQEQIQRIAGLAWSPNQQRLAIATADRHILLYDDAGERRDKFSTKPANPANGKNSYVIRGLAFSPDSTKLAVGQSDSIVYVYKLGESWNDKKVICNKFPQASAVTALIWLTSGSIIAGLEDGKVRALHSKSNKSQSLYGGDSICISLAANTKGTGFLSGHNDGTIIRYFMTDEAT-EPLGRVVQHPVPPFALAWPQGGFCAGGCDQRIVFYDSMGRQLRTFDHSRTEGEREFTVAACSPNGQAVAFGSFDRIRIFAWSPRQGAWSESATKEVACLYTLSSLLWRRDGARLALGSVSGAVLLFESVLRRTVWQDKFELIFVAPSQLLVRSLTEPSQALTIESQLGLEIDDVRIMGRDNYLVARTEESLILCDLTRNLSSEVPWTASGHHERFYFENPTVCLIFNVGELSLVEYGENSILGSVRTEFVNPHVISVRLNERGN--AKENKKLAFLLDAKTICVVDLISRMTSGQISHETKIDWLELSETAHKLLFRDKKLRLILVDNYTGKKQTLLSNISFVQWVPQSDVVVAQSNSNLAIWYNIDLPEHVTMQSVRGEAIEVLRENGRTVVRSQDGPSEHNYQLDEGLVEFGTAVNDSDFGRAVHFLESLGDKPAAKAMWHNLALIALEDGNLRVAQRCYAALGNVSKAYYLAGMIQQADEFEESSGSPGILCPEVRAKLALLGSDLRTAERIYLEQGDIESALKMYQQLGMWDEAVALAERRGYNRIAELKQQHMDYLLSSEQQEKAGQVLEEQGDLQQAMSLYMKANKPARAARLALKTPHILQDEQVMLQVTEGLVRSELYELAGDIAHRLSRPEAALALYRKGGAYARALEIGRVVAPQEVTALEEEWGDWLVSRKQLDASINHYIEAGATQKALEAAVGAKQWRKAVQIAKVLDEPELIQRYAVDLAKHLAFAGDLDGAEDMLVRANLHKDAIELLNRHGKWERAYLIGEKHLKAEQVRELFVQLAGTLEEQGKFRDAEKVLIAVNEPDLAIAMYKRRELYDSMIRLVERYHKDLLDSTHLHLARQLESRGKLKNAEMHFVASGDWKSAVHMYCSSGRWEDGYRVAKLKGTEGASQQVAYMWAKSMPTEGAVRLLSKLGLLDTAVGFACDSGQFEFAMELCKFAGKP-TDEVHLKIAMSLEDEGKFEAAEAEFLKANKPREAILMYQHAGDWQAALNVAENHLPDAVGEVLIGQASAALETSNYKDYEALLLRAHRPDLIIEHYKQESLYEDALRIAEEHYPSALNDLRRLQAQLQRGQAQAQAGEDAASISRSYLQKAAEFAKKEQFRKAAECLMQIDSSNAEDASTLERALLRAAEICNQFLEGQDAQELAQSLGPRLLAIKQIGPAAQLYLAADMPKQAVDVFIKTEQWSKARRLAKEIDPDLQLLAYVEQQQKASLKHEGNIEQLADIDIVSALDLLAEHGEWQRCLEKAKGLNPALLQKYVAVYAAQLIREGNCTTALGLYLSYGAPPIEAHFNIYTRIALDCLALRE-EQTERGTTWRQLRDFLFRLLQSLKATPAQSQTKFAASMEQFLLIAHYYATRAACKEVQALQPVALRLSLALLRHTDLLPVDKGFYEAGMDLRQAGREAEAFVMLNHYLDVCEAIEEGSGQLVDHSDLASTDFPSSVPLPEDIHLKNDPSLHEEVREWVLAVSMDQQVDQQLPTDDRGLYES-----SLGPNDLPCMLSGFPVRGRQPVTFQGSSNQVNRDVWSKFSVALKMSPGSGIADIISFTEKWQG---AANYVMH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**:::*** *: ::: :**: *: ::*:.* ** ::***: **:**:*:****: *:::*:::.:********:*:.*:*.*::***:**.*.********* *:****.* * :. *: ** :**** ::*:.**.::** :* ::*::* .*.*:**** ***::***: **.: *. *::: *. **:**** ..: ..***::** *.. *. ::***:** *:***.*..**.**::..**:**:*:* * **:. *.*: .**:. ***:::* *::**:**. *::.*.* *:. ***:::::***: :*. **::*:.*: .. :.::*: * *:::*:::*::.****:*.::*:* ** * **:.* .** :*:::*** .**:***.***:*****.*. ********:***:****:*** : ::*****:*:* ***.:***:. . * :**::::*****.**.:******:**** * * : * :*. .::**** ***:***....*.:**.*: **:*** .::*: : : * .*:* * :* . * *****:*****::*.:: **. ***:* .. ::***:.*: ::** :*: *:**::***.*:** :* : ** . .. .. * :*:*:**:* .: : ** ::**. ::..: ***:* *:*.:*:** :*: : :*::.: . *:.::*:*:*.:: *.:** *:.**:**. **:** *.:. .:* . ::: ::* .*::.*:** ***: .: . : ** * **.*: :*:::.*:. * **. *** *** **.:**:**:******* : **:***:.*:**:**: * .: : . :* :*:: * : : ** : .:.: ****:: .: *:**:*: :. * : *:* *:: * :*::**:::**:: :*:******:*:*:.::**.***** :* ***..**:**.::**:..::::** *:: . :**::*:** .. **:.**:*: :* .* ::***:****: *.**:**.*:***::::..*.*. *:**:**.::: * ::**: ** ***:***: ** **::*.**:**:**. * **. * .*** * *::*.::*:.** .:: .:::. *.:****:** * :::**: .:: **:**.::: *. *. *: : : ... .. :::* .: : :: :*.:* ::: .* . . :. ::***:. :** : :: :**:*: : : . :*:*** *: *:*:*.**: *:*.**:*:***:** : **::: * **::*:::.*..:*:::***: .*:*:*::*::.*. * :*:**:*:**::**:** .*.**:.:*.*. :****.*: : : : :* * :***.*: * :.* : ::::: .:: :**::******:*.: :. *..** :**::*****:*:*.**.***** : .* : **:::*::**: :.*:**: : :**:*: .**:* .**:* *: :**:*:***:*****:::* ** *:** **: * * . ***:::*:*: *: : *: .. .*:* *.** :* * : .. *::.* :* * ::.: ::", "identical_positions": 703, "similar_positions": 661, "identity": "39.78%" }, { "cls_id": "homologset.agr.RGD:620745", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R317-1", "uniprot_id": "UBQL1_MOUSE", "id": "Q8R317-1", "name": "Ubiquilin-1", "aln": "MAESAESGGPPGAQDSAADGG---------PAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHIDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDNSAQQTNAPGSTVTSSPAPDSNPTSGSAANSSFGVGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFASLVSSSSSAEGTQPSR-TENRDPLPNPWAPQTSQSSPASGTTGSTTNTMSTSGGTATSTPAGQSTSGPSLVPGAGASMFNTPGMQSLLQQITENPQLMQNMLSAPYMRSMLQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLSAMSNPRAMQALLQIQQGLQTLATEAPGLIP--GFTPGL-AAGN---------SGGSSGTNAPSTAPSE---------DTNPQGGTAEPGHQQFIQQMLQALAGVNPQLQSPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJP9-1", "uniprot_id": "UBQL1_RAT", "id": "Q9JJP9-1", "name": "Ubiquilin-1", "aln": "MAESAESGGPPGAQDSAADSG---------PAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHIDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDNSAQQTNTTGNSVTSSPAPDSNPTSGPAANSSFGLGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPNIMRQTLELARNPAMMQEMMRNQERDLSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFASLVSSPSSAEGTQPSR-TENRDPLPNPWAPQTPQSSPASGSTGSTTNTVSTSAGNATSTPAGQGTSGPNLVPGAGASMFNTPGMQSLLQQITENPQLMQNMLSAPYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLSAMSNPRAMQALLQIQQGLQTLATEAPGLIP--GFTPGL-AAGN---------SGGPAGTTAPSTAPGE---------DTNPQGGAAEPGHQQFIQQMLQALAGVNPQLQSPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UMX0-1", "uniprot_id": "UBQL1_HUMAN", "id": "Q9UMX0-1", "name": "Ubiquilin-1", "aln": "MAESGESGGPPGSQDSAAGAEGAGAPAAAASAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDHSAQQTNTAGSNVTTSSTPNSNSTSGSATSNPFGLGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMLSAAQEQFGGNPFASLVSNTSSGEGSQPSR-TENRDPLPNPWAPQTSQSSSASSGTASTVG--GTTGSTASGT-SGQSTTAPNLVPGVGASMFNTPGMQSLLQQITENPQLMQNMLSAPYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLSAMSNPRAMQALLQIQQGLQTLATEAPGLIP--GFTPGLGALGS---------TGGSSGTNGSNATPSE---------NTSPTAGTTEPGHQQFIQQMLQALAGVNPQLQNPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGS-QPS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWD9-1", "uniprot_id": "Q9VWD9_DROME", "id": "Q9VWD9-1", "name": "Ubiquilin-like protein", "aln": "MAE----GGS------------------------KRINVVVKTPKDKKTVEVDEDSGIKDFKILVAQKFEAEPEQLVLIFAGKIMKDTDTLQMHNIKDNLTVHLVIKAPTRNNEQPARQP-------------------ADVRQTPFGLNQFGGLAGMEALGAGSNTFMDLQARMQNELLNNGDMLRSLMDNPMVQQMMNNPDTMRQLITSNPQMHDLMQRNPEISHMLNNPDLLRQTMELARNPSMLQELMRSHDRAMSNLESVPGGYSALQRIYRDIQEPMMNAATESFGRNPFAGLVDGGGSGAGNNPQQGTENRNPLPNPWGGANSGTNGTVGGSG-----------------AGNPTG--DLPP---NNVLNTPAMRSLLQQMADNPAMMQNLLNAPYTRSMMESMSQDPDMAARLLSSSPLMSNNPALQEQVRQMMPQFMAQMQNPEVMNMLTNPDAMNAILQIQQGMEQLRSAAPGLVGTLGIPPPPPGAGTGTNPASGDGSGGNSGASTNNVSPSSGLNAGTGTPNLAPGGGPNAQLFNDFMMRMLNGMSNNADNTQPPEVRYQSQLEQLNAMGFVNRDANLQALIATFGDINAAVERLLSLNQLSLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48510-1", "uniprot_id": "DSK2_YEAST", "id": "P48510-1", "name": "Ubiquitin domain-containing protein DSK2", "aln": "----------------------------------MSLNIHIKSGQDKWEVNVAPESTVLQFKEAINKANGIPVANQRLIYSGKILKDDQTVESYHIQDGHSVHLVKSQPKPQTASAAGANN------------------ATATGAAAGTGATPNMSSGQSAGFN--PLADLTSARYAGYLN---MPSADMFGPDGGALNNDSNNQDELLR-----------------MMENPIFQSQMNEMLSNPQMLDFMIQ------SNPQLQAMGPQARQMLQSPMFRQMLTNPDMIRQSMQFARMMDPN---AGMGSAGGAASAFPAPGGDAPEEGSNTNTTSSSN-----------------TGNNAG------------------------TNAGTNAGANTAANPFASLLNPALN-------------PFANAGNAASTGMPAFDPALLASMFQP------------------------------------------------------------------------------------------------------PVQASQAEDTRPPEERYEHQLRQLNDMGFFDFDRNVAALRRSGGSVQGALDSLLNGDV----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: :*: ::* . * :* : :** : : : **::***:** :*:. : *:*. :**** . . .* . . . * . .::. .: * . : :* : *. * * .* : .:.: :*: *::** : * *: ** *:: ::: ** : . * .* : : : . *:. . ** ::. * . : . * *. . .. : . : :*: : .. * *: : ::. *: . . : * :: .* :* :. : : ** *:: **.**. ***.: : *: ** : *.::.*:: **. ", "identical_positions": 71, "similar_positions": 120, "identity": "11.53%" }, { "cls_id": "homologset.agr.RGD:620746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G1R8-1", "uniprot_id": "A0A8I6G1R8_RAT", "id": "A0A8I6G1R8-1", "name": "", "aln": "MREGAAERRRGHRRPMLLPFLLPLFCPALSEQIRYKIPEEMPTGSVVGNLAKDLGFGVQELPTRKLRISSEKPYFTVSSESGELLVSSRLDREQICGKKLVSKQRGAKKMREGAAERRRGHRRPMLLPFLLPLFCPALSEQIRYKIPEEMPTGSVVGNLAKDLGFGVQELPTRKLRISSEKPYFTVSSESGELLVSSRLDREQICGKKLVCSLEFEAVAENPLNFYHVSVELEDINDHTPKFAHTSFELQISESAQPGTRFILEVAEDADIALNSLQNYKLSLSPSFSLVNKEKQDGRKYPELVLEKTLDREQQSYYRLVLTALDGGDPPLSSTTELRIQVTDANDNPPVFDQEVYRVRLPENVPPGTTVARVTATDKDEGVNSEITYSFHRAG-----QVFGLNSNSGEITTQRTLDFEETKEYSIVVEARDGGGL--VAQCTVEINIQDENDNKPEITVHSLLETIPENAPPGTLISLIKIHDRDSGENGEVNCRLDSEAPFKIISSSKNSYKLVTDRTLDRELTPEYNVSIMATDGGKPPLSSSTKVTLHVGDVNDNAPLFHQASYLVYIAENNPPGASIAQVSASDPDLGSNGHVSYSIIASDLEPKSLWSYVTVNAQSGVVFAQRAFDHEQLRSFQLTLQARDQGSPALSANVSMRVLVGDRNDNAPRVLYPALEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGEKDAARQRLLVGVRDGGQPPLSATATLLLVFADSLQEALPDLSDRSLPPDPQ-AELQFYLVVALALISVLFLLAVILAIALRLRHSSSPS-AWNCFQPGFCSESKPVVFPNYSEGTLPYSYN-LYGAHAGKTECNFLKCSEP--LSSGQGLLCPESSGALFPLCDSSEPTS-HPEPPQAPPNTDWRFSQAQRPGTSG-----------------------SQNGD------ETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGTGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN---------------AAGKRDGKAPAGGNGNKKKSGKKEKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5G6-1", "uniprot_id": "PCDG7_HUMAN", "id": "Q9Y5G6-1", "name": "Protocadherin gamma-A7", "aln": "--MAAQPRGGDYRGFFLLSILLGTPWEAWAGRILYSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIIS----------------------------------------------RGR-------------------------------------------------------------TQLFALNQRSGSLVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPK-LPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDGPGS--LTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLEPSDGPYNYDLTLYLVVAVATVSCVFLAFVLVLLALRLRRWHKSR-LLQASEGGLANVPTSHFVGMDGVQAFLQTYS-HEVSLTADSRKSHLIFPQPNYVDMLISQESCEKNDSLLTSVDFQECKENLPSIQQAPPNTDWRFSQAQRPGTSG-----------------------SQNGD------DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN---------------AAGKRDGKAPAGGNGNKKKSGKKEKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UN70-1", "uniprot_id": "PCDGK_HUMAN", "id": "Q9UN70-1", "name": "Protocadherin gamma-C3", "aln": "MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSG---------------------------------------------ASR--------------------------------------------------------------RFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLYPRP---GGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQK-KNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQVLGAES-APPGQQAPPNTDWRFSQAQRPGTSG-----------------------SQNGD------DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN---------------AAGKRDGKAPAGGNGNKKKSGKKEKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N6P0-1", "uniprot_id": "A0A8M1N6P0_DANRE", "id": "A0A8M1N6P0-1", "name": "", "aln": "----MNRRLYPISFFAFFVALLLFILKIASADLSYNIPEETKRHYVIANIAKDFKMDVKQLSARKARIDPEDS----------------------------------------------------------------------------------------------------------SKRYCDINPNTGDLFVAETIDREELCGSRMSCILNYELVLENPLDVHRIIFQIQDINDNTPRFPNERINFEIRESAVKGQRFRLDEAHDSDIGKNSINDYSLEKNEHFVLTVQ-TADEEKYAELVLEKELDREQQKEMDLILTATDGGLPQRSGTAVIHITVLDANDNVPVFDQPIYKVTLAENTPSGTDIIRVSATDADEGPNGEVTYEFSRISDK-TAKLFSIDKTTGQILVKGEIDYESEKNYELGIQAKDASGL--ASIAKVIIDITDVNDNPPRIILKSLNNPIPENSEPGAEVGIINVQDKDSGENRQIRCSVQQNVPFKLNPSVKNYFSLVTTKALDREKESDYNITITATDGGSPPLSTSMTIHLFVSDVNDNPPVFEQQAYSAYINENNKADTSVCSVSANDPDWRQNGTVLYSLVPSEVSGVPVSSFLSINGDTGVIHAVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQILYPVP-DGKTLMTEMVPKATLSGSLVSKVIAVDADSGQNAWLSYQILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDNAQPSLSTTCVVNLLISDNLSEVP-ELKDMS-YEDN-NSKLTSYLIIALVSVCTFFLTFIILMLAVKFCHRRKPRLLFDGAVAVPSAYLPPNYADVDGAGTLRSSYN-YDAYLTTGSRTSDFKFVSSYNENTLPASGTLNKEHNIHFGSSIITLDVTGDKVEQKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEA---------------TATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6A8-1", "uniprot_id": "A0A8M1N6A8_DANRE", "id": "A0A8M1N6A8-1", "name": "", "aln": "----MEYALFWGRFFACFVAVILLLPITVCADLNYNIPEETKSQYVIGNIAKDLGIDVKQLSARKSRIDTEDI----------------------------------------------------------------------------------------------------------SKRYCDINMKTGDLIVAETIDREELCGSRMSCFLNYELVLENPLDVHRIIFQIQDINDNAPRFPNERINFEITESADKGQRFRLHEAHDSDIGRNAVNGYLLEKNNHFYLNVHDTAYGGKYAELVLEKELDREQQKEMDLILTATDGGSPQRSGTAVIHITVLDANDNVPVFDQPVYKVTLAENTPSGTEIIRVSATDADEGPNGEVTYEFSRISDK-ASKQFSIDKKTGQILVTEKIDYESEKNYEIGIHAQDGSGL--ASTATVIIDITDVNDNPPRIILKSLNNPIPENSEPGAEVGIINVQDKDSGENRQIRCSVQQNVPFKLNPSVKNYFSLVTTKALDREKESDYNITITATDGGSPPLSTSMTIHLFVSDVNDNPPVFEQQAYSAYINENNKVGTSVCSVSANDPDWRQNGTVLYSLVPSEVSGVPVSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQILYPVP-DGKTLMTEMVPKATLSGSLVSKVIAVDADSGQNAWLSFQILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDNGQPSLSTTCVVNLLISDNLSEVP-ELKDMS-YEDN-NSELTSYLIIALVSVCTFFLTFIIMMLAVKFCHRRKPRLLFDGAVAVPSAYLPPNYADVDGAGTIRSSYN-HDAYLTTGSRTSDFKFVSSYNENTLQAGGSLKSVQSDSFGAHVVTLINTEEAEEQKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEA---------------TATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6G0-1", "uniprot_id": "A0A8M1N6G0_DANRE", "id": "A0A8M1N6G0-1", "name": "", "aln": "---MAKTSKLCLGKWRLWITSLLFC--VTAADVRYSVPEETKTKFVIGNLSKDVNLDYNRLRFRKARLDYQG-----------------------------------------------------------------------------------------------------------DRRYCEIDLDSGNLFVSERIDREMLCGTASPCIMHFEFILENPLELHNIALEVQDVNDNPPVFPKGSIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYILSQNKHFVLDTK--SSKDRYVDIVLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDMNDNAPLFLQPLYNARLSENSALGTSVIKITATDEDEGANGEIKYYINHLSDN-TKQLFKIDENYGEISVIGQLDHEKASSYEVEVQAEDGGGQ--TGHCKVVIEIDDVNDNAPVISVKSLKNKIPENTTPGTEIAVINVKDQDSGENSRISCSISPNLPFQLQPYIKSYFILTTSSSLDREQIDNYNVTIIATDGGIPPLFSNISLNIQVSDVNDNSPRFELQSYFIYISENKQAGTSVCSVSANDPDWRQNGTVLYSLVPSEVNGVPMSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQILYPVP-DGKTLMTEMVPKATLSGSLVSNVIAVDADSGQNAWLSYQILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDNGQPSLSTTCVVNLLISDNLSEVP-ELKDMS-YEDN-NSKLTSYLIIALVSVCTFFLTFIILMLAVKFCHRRKPRLLFDGAVAVPSAYLPPNYADVDGAGTIRSSYN-YDAYLTTGSRTSDFKFVSSYNENTLPAGGILDKSK---IDFNMLRLSDVGECTEQKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEA---------------TATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6D6-1", "uniprot_id": "A0A8M1N6D6_DANRE", "id": "A0A8M1N6D6-1", "name": "", "aln": "------MKTMLDAMIQHSVLILTLLVYIARGQVSYSIPEEMAKGSMVGNIAQDLGLDLQRLKSGKARIFSRD-----------------------------------------------------------------------------------------------------------STEYIELNRNTGLLLIKEKMDRESLCAKTTPCALHLQMILDNPMELYTITVEITDINDNAPNFQKRDFKFEISESAMVGARFMLGKAFDPDVGTNSLQSYSLKPTDKFRLELQSQADGSKNVEMILQKALDREMQSSFTLLLEAFDGGDPVLSGTVQIHIAVLDINDNAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNSEVTYYISDTMDSVMADMFLVNEQTGELILNGHFDYEKVSHYELTIHAKDQGGL--SNACKVIIDVLDVNDNSPSINILSSSHSVSEGSKFGTVIAMLNVDDLDSGASGQVQCVMSEEIPFVIKSQSSNFFSLQTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQISDVNDNPPVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQNARVSYILEDSTVSGVSVSSYVSVHPDSGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQVLYPVQ-TGTSVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEVLSEFTDFT-HEKQYNDSLTFYLVLALAAVSFLFITCVVVIISVKIYRWRQSRFLYQSNLPVIP-YYPPHYADTGVTGTLPHGYN-YEVCMTTDSRKSDCKFSTLGGQNVLVVDPSFAETMKHTIKKNSS-IDDLQSTESQKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEA---------------TATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6Q0-1", "uniprot_id": "A0A8M1N6Q0_DANRE", "id": "A0A8M1N6Q0-1", "name": "", "aln": "--------MAFFVMWHGAVFFMILSRYAVKGQISYSIPEEIPKGSIVENNSQGLGLDLKRLNSGKARIFAGD-----------------------------------------------------------------------------------------------------------NRRFVGLNKEKGILLTEEKIDREALCAKTTPCASHLQLILENPMQKYDVTVEIIDINDNAPSFPKGEIRFEISETAVTGARFMLENPIDLDVGTNSHLSYSLKPTDNFILSSQGQTDGDKNMEMVLQKALDRENKEKLSLMLTAVDGGEPSLTSTVRIHVTVLDANDNPPVFSQRVYKATFAEITPKDTVIASVSASDADEGSNAIITYYMSSTGD--VNDLFTVDTRSRDIRLKGSADFEKASRYQFNIQARDQGGL--SDSCKVIIDLTDINDNKPIISIVSMSNSISEQSRPGTVVAMLNVNDFDSGMNGRVHCYRNDNIPFTIAS-SSSFFSLQTEQELDREKEAEYNISVICSDEGVPALSSSVSLRVQISDVNDNAPVFEKSNYEAFVVENNTPGLSIFTVKASDADWNQNARVSYILEDSIVNGVSISSYVSVHPESGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDHNDNAPQVLYPVQ-TGASVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEVLSEFTDFT-HEKQYNDSLTFYLVLALAAVSFLFITCVVVIISVKIYRWRQSRFLYQSNLPVIP-YYPPHYADTGVTGTLPHGYN-YEVCMTTDSRKSDCKFSTLGRQNVLVVDPSFTETMQHTIKKKCS-IDGLRITKSQKPPNTDWRFPPNQRPGPSGQHRFHTLQQRWTPYEKSRAGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANE-----------------------ERNTHRFETSGRK------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *.:.** : : .. : * *: :. .* :. :*** :*. * : : :: :: . : . : *:**: * * :..:* * . * :: * . * *:. *: * *. . * * : : :::*:. **** . *:* * *** * :.: :.: * * **: *:* *.. * . .: : : * * *** *. : * : . * :: : *.*. :.. :.*.* . ..* : : * *** * : : * :.* : *: :.:: : * *:* . : * ** : .. : * * **** **::: . * * *.* : : :.* ***.* * :: **: . .: :.. * * .*. : : : . . : :.::: :.*:: : .:*:* :.: . * * * *::*::: : : *.***.*.:*** :: *:.: * **:.*:. * *:*:*****: : :.: .** :** .*:: * * : : * :* * : :.* .:*. *:. : : .::. *. :: . .* **:::: :. *: :. : .:. : .. . : : : :. . . * ********. ****.** .: * **.*** ::* ****: *: : . :. .. *: ", "identical_positions": 172, "similar_positions": 244, "identity": "15.78%" }, { "cls_id": "homologset.agr.RGD:620747", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MR3-1", "uniprot_id": "S12A9_MOUSE", "id": "Q99MR3-1", "name": "Solute carrier family 12 member 9", "aln": "-------------------MASESSPLLAYRLLGEEGAAFPP-----NGAGVSGVPS--------------------SRKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYIILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESILDVFGADATG---SSGIQVLPQGYGWNLLYGSLLLGLVGGVCTLGAGLYARASFLTFLLVSGSLASVLVSFVAVGPRNIPLAPRPGTNASSVPHRHGHFTGFNGSTLRDNLGAGYAEDYTTG---AMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRALLQEDYGFFRDISLWPPLVLIGIYATALSASMSSLIGASRILHALAQDDLFGVILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGP---SSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPAEGTREGG---SPALSTLFP----PPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPE-RLSRGSSSSAQLHHVDVWPLNLLRPRGGPGYVDVCG-------LFLLQMATILSMVPAWHSAR-LRIFLCLGPREAPG---AAEGRLRALLSQLRIRAEVQEVVWGEGAETGEPE---------------------------------------------------------------------------------------------------------EEEGDFVNGGRGDEEAEALACSANALVRAQQGRGTVGGPGGPEGRDGEEGPTTALTFLYLPRP----------------------------------------------------------------------------PAD-----PARYPRYLALLETLSRDLGPTLLIHGVTPVTCTDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HR0-1", "uniprot_id": "S12A9_RAT", "id": "Q66HR0-1", "name": "Solute carrier family 12 member 9", "aln": "-------------------MASENSPLLAYRLLGEEGAAFPP-----NGAGGSGVAS--------------------ARKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESILDVFGADVTG---SSGIKVLPQGYGWNLLYGSLLLGLVGGVCALGAGLYARASFLTFLLVSGSLASVLVSFVAVGPRNITLAPRPGTNGSSVPPRHGHFTGFNGSTLKDNLGAGYAEDYTTG---AMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIIAVAYTFFIYILLFFLSSFTCDRALLQGDYGFFRDISLWPPLVLIGIYATALSASMSSLIGASRILHALAQDDLFGVILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLSALLTARGGP---SSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDLAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPAEGTREGG---SPALSTLFP----PPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPE-RLSRGSGSSAQLHHVDVWPLNLLRPRGGPGYVDVCG-------LFLLQMATILSMVPAWHSAR-LRIFLCLGPREAPG---AAEGRLRALLSQLRIRAEVQEVVWGEGAEAGEPE---------------------------------------------------------------------------------------------------------EEEGDFVNGGRGDEEAEALACSANALVRAQQGRGTGGGPGGPEGRDGEEGPTTALTFLYLPRP----------------------------------------------------------------------------PAD-----PARYPRYLALLETLSRDLGPTLLIHGVTPVTCTDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BXP2-1", "uniprot_id": "S12A9_HUMAN", "id": "Q9BXP2-1", "name": "Solute carrier family 12 member 9", "aln": "-------------------MASESSPLLAYRLLGEEGVALPA-----NGAGGPGGAS--------------------ARKLSTFLGVVVPTVLSMFSIVVFLRIGFVVGHAGLLQALAMLLVAYFILALTVLSVCAIATNGAVQGGGAYFMISRTLGPEVGGSIGLMFYLANVCGCAVSLLGLVESVLDVFGADATG---PSGLRVLPQGYGWNLLYGSLLLGLVGGVCTLGAGLYARASFLTFLLVSGSLASVLISFVAVGPRDIRLTPRPGPNGSSLPPRFGHFTGFNSSTLKDNLGAGYAEDYTTG---AVMNFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPLGTIVAVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATALSASMSSLIGASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYSWGLVQLVLLAGKLNTLAAVVTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGGSLLLMGLLAALLTARGGP---SSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGNPRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDRAQVKAFVDLTLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPADSTREGS---SPALSTLFP----PPRAPGSPRALNPQDYVATVADALKMNKNVVLARASGALPPE-RLSRGSGGTSQLHHVDVWPLNLLRPRGGPGYVDVCG-------LFLLQMATILGMVPAWHSAR-LRIFLCLGPREAPG---AAEGRLRALLSQLRIRAEVQEVVWGEGAGAGEPEA--------------------------------------------------------------------------------------------------------EEEGDFVNSGRGDAEAEALARSANALVRAQQGRGTGGGPGGPEGGD-AEGPITALTFLYLPRP----------------------------------------------------------------------------PAD-----PARYPRYLALLETLTRDLGPTLLVHGVTPVTCTDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BFP5-1", "uniprot_id": "S12A9_DANRE", "id": "A2BFP5-1", "name": "Solute carrier family 12 member 9", "aln": "-------------------MANEHSPLLVHGVYSMMGNAEDSR----GGSAGTGEASNPKTD---------------PRKLNTFFGVMVPTILSMFSIVLFLRTGFVVGHAGLLHGLLMLFVAYFIISLTILSICAISTNGAVEGGGAYFMISRSLGPEFGGSIGLMFYLAKVCACGVYVLGLVEAIMDVFGQDPGSSV-AQGLRVLPQGYWYTVLYSSVVLLLCMLVCLVGAHIYAKASFLILLVVTVSLISIIISPLIVSPQGFNITHTYGNNHSVTVSPS--YTGFNSTTLKNNLGPRYSLDYSTN---TMMSFATVFAVMFTSCTGIMAGANMSGELKNPSESIPKGTIMAVAYTFTVYVLLYLLLSSTCDRSLLLNDYAVFQRVNVWPPFVTIGVYCASLSAAMCSMIGASRILHALALDQLFGLPLAPAAVTSSSGNPWVSVLYTWALVQCTLFAGQLNVIAGIVTVFYLLAYAAVDLACLALEWASAPNFRPTFQFFSWHTCLLGIISCVVMMFVINPVYSSASIVLLLLLLLFLHYRSPT---SSWGYISQALIFHQVRKYLLMLDSRKDHVKFWRPQVLLMVSNPRSSCQLICFVNQLKKGGLFVLGHVQIGDLDVLPADPVQPQYNFWLSLVDKLGVKAFVDLTLSPSVRQGTQHLLRITGLGGMKPNTLVLGFYDNSYPEDYFLQDPVFCKGDRSEGDNFGVDLPSLQAHFP----PVRHAESPRALQPQEYVSIIQDAIKMGKNICLARYFFQLPPESKGATYMWGKDSMDTIDVWPTNLLTP-GSASYADVGS-------LFLLQMACVLNMASGWRRAR-LRIFVCVESESEDQGWLAKEEQFRELLGKLRIRAAIKIVAWDNVARMVRGP-----------------------------------------------------------------------------------------------------------------NTESQPVSEDFLCAVNGLLKEHS-------------------STAAVRFLYLPDP----------------------------------------------------------------------------PSS-----CELSQQYLTQLDTLTRDLGPTLLIHGVTPVTCTEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ75-1", "uniprot_id": "Q9VJ75_DROME", "id": "Q9VJ75-1", "name": "Solute carrier family 12 member 9", "aln": "----------------MSASAEQETAPIANSRSGRTGSVFRSFGSLFGGSQNSGDRPHTPQDGDGYVEFGMQDPDRSGRTLGTFAGVFSPVALSMFSALVFIRVGYIVGNAGLYVTLLQFLIAYGILLFTVASVCAISTNGAIEGGGVYFMISRTLGLEFGGSIGTLFFFANVVGSAMAISGCTEGIMDNFG--PRGHF-VSGDSHLPDGDWWRFLTSSMINTLQLLVCLVGAALFAKTSVIILATVTVCLFATYFSFLFVGATNNTIP-VPGDNILSNTTTFLDYTGLNATTLRDNLGSHYGRDYTSNG--KQVDFSTTFGVLFSGVTGIMAGANMSGELKNPSKSIPYGTLSAVAFTFVSYIILSFLMSCTTPYFTMQNNYLFLMPVNLWPPFTAIGILTATFSTSLSNLIGSSRILEALSKDQVFGSLLNFVIHGTWKGNPIAAVAVSWCLVECILLIGSFNIIAQINSVLFMLSYLATNLACLGIELTGAPNFRPLFKFFTWHTCLVGLLGTLIMMFVINFIYASSCIILCLILVIALHLFSPATQAAQWGSISQALMFHQVRKYLLMLDPRKDHVKFWRPQILLLVSSPRSCCPLVDFVNDLKKSGLYIIGHVKLGDFKGIEDAEDNQQ---WWSFLDHMRVKAFTEVTLSRSIREGVQHLIRLSGIGAMKPNTIILGFYDSEAPRDFFQNGSSPYKTDDFN---------NGEIQNF----PIRRDGDPKQFQIQEYVQILCDTLRMKKNLCLCRNFQRLDKN-----FISMSKHVKYIDVWPINIFNPTSGDP-FDMVS-------LFMMQLAVIM--LAKWKHLR-VRIFLCEANDERTVGTFDTQTPQMEIFSKMKLEQSLKELRITADIVEIQEWSRD-----------------------------------------------------------------------------------------------------TDFSRHARTLKQFTAQADNVVLEDDDEVGEETLNRSLLYMQRANQIIRERSDQTALSFIYLAAP----------------------------------------------------------------------------PKLSAPDFAQRSASYMELLTELTADLPPTILVHGVSTVTSTTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38329-1", "uniprot_id": "VHC1_YEAST", "id": "P38329-1", "name": "Vacuolar cation-chloride cotransporter 1", "aln": "MVSRFYQIPGTHRPSSAISSSNESSSLLSARRISQTYFNYQATPECQKVSSKYDPDNPN------------------KDKLGTYDGVFVPTALNVLSILMFLRFGFILGQLGIICTIGLLLLSYTINLLTTLSISAISTNGTVRGGGAYYMISRSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIEPLLYNLGYSAQGEPPAALGELLPRGHWHEFTYATVILFLCFSVAFVGSQTVSRAGNILFLVLAASIFSIPLSALIRSP---------------FTEGGISYTGPSWQTFHDNLLPHLTKGAAGSLLKGKETFNDLFGVFFPATAGIFAGAGMSSELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPRRSLYDEVQIIQTISSVQWVIFMGEMATSLFSIIVGMLGAAYVLEAIAKDNIIPGLEIFAHS------PLYSLIFTWILTQLCLFS-DVNKIATFITMTFLMTFVVMNLACFLLGISSAPNFRPSFKYFNRYTTAIGALLSVVAMLIVDGISASVLFLAMILLFLFIHYFSPP---KSWGDVSQSLIYHQVRKYLLRLR--QDNIKYWRPQILLFVDNPRTSWNLIRFCNHLKKGGLYILGHVAVTADFPKQLNELKTQQKAWMKIRDMAAIKAFVQVGTGPSLIWGIRNVFIGSGLGGMKPNITVVGFFDLESYRKHIPQSRSQNNLQKQVEIKATVPRSTCSDVKINVPLPTDECKNETKVNVQQWVQIVEDLSLMQSNIAIAHGFKNLEIP----NKRDSCFPKKTIDLYPIQMCGKVEAKGDQPAAITTNFDTYTLILQLAAILVTVPEWKRTHSLRVILFVEQEYHRT---NETQRMKKLLQVLRIDAEVLVVSLDQFRVYNTIVKGDPIVFDYVNSKLADNEWWKDLVEARDTLKPKRRFSTIEPQTIAKQFTQSRKYTSGVQKLGVSFTMNTRMPTNRIDTPCESEDSDLDTDLTSIRDAFSASTNISVGKDLTTKSKTGSDRTNLLVKNLQSDVSTQSLRPVFSSNTLPRTRVVEDGTGEQPTLIPIAEPDLSNGNGTGSGIGNGNKLKKPVLPELSPCCSKDSLVTAMQNLGFNDLPSTAQHLVLNDVMTQMSKSSDLIFSTLPVPALGTHEDHDASLQYVEDLDIWLEGLPPCMLINSQTMTVTTAL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: :. : . . : . .*.*: **. *. *.::* ::*:* *:::*: *: : ::::* * :* *:.**:***::.***.*:****:** *.***** :*::.:* ..: * * :: :* . ** * . .::: * *. :*: :::. : : :: .: : .* : .. :** . *:::** . . : . * *.*:* . :**:***.**.**:.**.:** **: .: :** * :: : . : : : .: :. . :* ::: : : .::*:: :*.*:: *::: . * :: :* *.: *: ..* :* . :: ::::: . :*:*: : :.****** *. *. :* :* :: *:::. :. :: :* : . . .** :**:*::******** * ::::*:****:**:*..** . *: : *.***.**:::*** : : * * .: * :***.:: . *: * :::: :*:*.**** ::**:* ...: . : . * . .. *::* : * * .*: :.: * . :*::* :: . :::*:* :: . *: : :*::: :: ::: : : :: . : : . :: :. * * *: * .* * :*::. : .. * *", "identical_positions": 174, "similar_positions": 280, "identity": "14.85%" }, { "cls_id": "homologset.agr.RGD:620748", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJH2-1", "uniprot_id": "GP173_RAT", "id": "Q9JJH2-1", "name": "Probable G protein-coupled receptor 173", "aln": "MAN---TTGEPEE-----------VSGALSLPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYFLLDLCLADGIRSAICFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVTRYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRYFKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQAAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQLGRMFYAITLLFLLLWSPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWGTGGAPAPREPYCVM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PI62-1", "uniprot_id": "GP173_MOUSE", "id": "Q6PI62-1", "name": "Probable G protein-coupled receptor 173", "aln": "MAN---TTGEPEE-----------VSGALSLPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYFLLDLCLADGIRSAICFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVTRYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRYFKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQAAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQLGRMFYAITLLFLLLWSPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWGTGGAPAPREPYCVM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS66-1", "uniprot_id": "GP173_HUMAN", "id": "Q9NS66-1", "name": "Probable G protein-coupled receptor 173", "aln": "MAN---TTGEPEE-----------VSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYFLLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVTRYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRYFKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQAAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQLGRMFYAITLLFLLLWSPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWGTGGAPAPREPYCVM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I918-1", "uniprot_id": "GP173_DANRE", "id": "Q9I918-1", "name": "Probable G protein-coupled receptor 173", "aln": "MANGNASSDGPGNPLAAVVSTTGGVMGGAPSSAVSTYVKLVLLGLIICISLVGNLVVSLLVLRDRALHKAPYYFLLDLCLADTIRSAVCFPFVLVSIKNGSAWTYSVLSCKVVAFMAVLFCFHAAFMLFCISVTRYMAIAHHRFYSKRMTFWTCVAVVCMVWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRYFKANDTLGFMLMLAVLILATHVVYMKLLLFEYKHRKMKPVQMVPAISQNWTFHGPGATGQAAANWIAGFGRGPMPPTLLGIRQNLHNQNRRLLGMEEFKAEKQLGRMFYVITLFFLVLWSPYIVACYWRVFVKACTIPHRYLSTTVWMSFAQAGVNPIICFFLNKDLKKGLLAHLPPCCRTPPQLPREPYCVM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ::. * : * *. . .:.*:**********:*:**.** ::*****::****************** ****:******.*:::**:**:*.****:*********************************:****:***.**:**.*************************************************: ***.** *******:*************************************************** * .******:*.*.*********.***:**:******************::*****:*:********.****:**:******* * :* * . ********", "identical_positions": 300, "similar_positions": 50, "identity": "77.52%" }, { "cls_id": "homologset.agr.RGD:62075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DBG6-1", "uniprot_id": "RPN2_MOUSE", "id": "Q9DBG6-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "aln": "MAPPGSSAVFLLALTITASVQALTPTHYLTKQDVERLKASLDRPFTDLESAFYSIVGLSSLGVQVPDVKKACTFIKSNLDPSNVDSLFYAAQSSQVLSGCEISVSNETKELLLAAVSEDSPIAQIYHAVAALSGFGLPLASNEALGALTARLGKEETVLATVQALQTASHLSQQADLRNIVEEIEDLVARLDELGGVYLQFEEGLELTALFVAATYKLMDHVGTEPSMKEDQVIQLMNTIFSKKNFESLSEAFSVASAAAALSQNRYHVPVVVVPEGSTSDTQEQAILRLQVSNVLSQPLAQAAVKLEHAKSAATRATVLQKTPFSLVGNVFELNFKNVKLSSGYYDFSVRVEGDSRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQSLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTVIFHLGHAAMLG----LMYIYWTQLNMFQTLKYLAVLGTVTFLAGNRMLAQHAVKRTAH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25235-1", "uniprot_id": "RPN2_RAT", "id": "P25235-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "aln": "MAPPGSSAVFLLALTITASTQALTPTHYLTKHDVERLKASLDRPFTSLESAFYSIVGLNSLGAQVPDVKKACAFIKSNLDPSNVDSLFYAAQSSQVLSGCEISVSNETRDLLLAAVSEDSSVAQIYHAVAALSGFGLPLASHEALGALTARLSKEETVLATVQALHTASHLSQQADLRNIVEEIEDLVARLDELGGVYLQFEEGLELTALFVAATYKLMDHVGTEPSIKEDQVIQLMNTIFSKKNFESLSEAFSVASAAAALSQNRYHVPVVVVPEGSASDTQEQAILRLQVSSVLSQPLAQAAVKLEHAKSVASRATVLQKMPFSLVGDVFELNFKNVKLPSGYYDFSVRVEGDNRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTVIFHLGHAAMLG----LMYVYWTQLNMFQTLKYLAVLGTVTFLAGNRMLAQQAVKRTAH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04844-1", "uniprot_id": "RPN2_HUMAN", "id": "P04844-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "aln": "MAPPGSSTVFLLALTIIASTWALTPTHYLTKHDVERLKASLDRPFTNLESAFYSIVGLSSLGAQVPDAKKACTYIRSNLDPSNVDSLFYAAQASQALSGCEISISNETKDLLLAAVSEDSSVTQIYHAVAALSGFGLPLASQEALSALTARLSKEETVLATVQALQTASHLSQQADLRSIVEEIEDLVARLDELGGVYLQFEEGLETTALFVAATYKLMDHVGTEPSIKEDQVIQLMNAIFSKKNFESLSEAFSVASAAAVLSHNRYHVPVVVVPEGSASDTHEQAILRLQVTNVLSQPLTQATVKLEHAKSVASRATVLQKTSFTPVGDVFELNFMNVKFSSGYYDFLVEVEGDNRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTIIFHLGHAAMLG----LMYVYWTQLNMFQTLKYLAILGSVTFLAGNRMLAQQAVKRTAH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q02795-1", "uniprot_id": "OSTD_YEAST", "id": "Q02795-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MQFFKTLAALVSCISFVLAYVAQDVHVSFPSTAGKSRVMIGKVEPRIG-IDETVPTTITVED--------------------------PNEVIQVN---------------FAIESTNKPFQN------------------------------------------------------------------------------------TLLIGLPNKNLEMAFEPEIKDNGKLSMYKYRIDLAKLDAALLQEASRSPEPIKAT-----------------------------------------------------------------------------LILASSTAKPKENLFREILQLNLNFDVDHSDSSLVDK--FGIKPEIHHIFHAEPKRVAKPIAVIFVLIIFITILSLIVTWLNSCAAAFNNIPTGVTAVYFLGFIATIVGFEVIFARYYLGTSIFETLFSSLYLGAPGLLTSTKFLRSFGQTI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*:* :. . *** * .*. * .. * :: ::* :. :** . : .*: ::***: *:: *: :.: : : .: : :.* .:* . ::.: : :. .. * :: :::* . * **. * * . *. *: :: :: :: ::* :.: *:::.: * * **:*:*: ** .. :: *. :*: .:* *:. *:. * . * : * ::.**. * : :: *: .:*:** **: :*:..::* . . . ", "identical_positions": 58, "similar_positions": 115, "identity": "9.13%" }, { "cls_id": "homologset.agr.RGD:620751", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q767I8-1", "uniprot_id": "PCDA4_RAT", "id": "Q767I8-1", "name": "Protocadherin alpha-4", "aln": "MEFSWGSGQESQRLLLSFLFLAIWEPGNSQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPTFPTTQKNLFIAESRPLDTWFPLEGASDSDIGINAVLTYRLSPNDYFSLEKPTNSERVKGLGLILRKSLDREETPELFLVLTVTDGGKPELTGSVQLLITVLDANDNSPVFDRSLYTVKLPENVPNGTLVVKVNASDLDEGANGEVMYSFSTDISPNVKNKFHIDPVTGEIAVKGYIDFEECTSYEILIEGIDKGQLPLSGHCKVIVQVEDINDNAPELEFKSLSLPIRENAPVGTVIALISVFDPDTGVNGQVTCSLTPQVPFKLVSTFKNYYSLVLDSALDRETTADYKVVVIARDGGLPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGAHIFTVSAVDADSQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLEPEAGISGGIVSRLVSRSVGAGHVVAKVRAVDADSGYNAWLSYELQSSEGNSRSLFRVGLYTGEISTTRSLDEADSPRQRLLVLVKDHGDPAMMVTATVLVSLVENGPLPKAPSRVSTRVTNAEASLVDVNVYLIIAICAVSSLLVLTLLLYSALRCSTVPSESVCGPPKPVMVCSSAVGSWSYSQQRRQRVCSGEYPPKTDLMAFSPSLS---DSRDREDQLQSTEDSSGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQPGPGELPDKFIIPGSPAIISIRQESANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5I0-1", "uniprot_id": "PCDAD_HUMAN", "id": "Q9Y5I0-1", "name": "Protocadherin alpha-13", "aln": "MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** .* ..::*** :*:** **.*..*****:********************************** :**************************************************:********* ** ::*.::****** :* ***:****:***:*:.*****.*****:*: .. *::..*.*:***:***** * *:**.:*********:******:**.***:* * :*:*.*.: **. *****:*:**:* *:*:**:::*** : * * * *:* .*** .** :**** . *** :*.:***::*::***.::*:* *:******: :.********:: .::****** * *:* ******:***:********:***************:.: *::** ***** *********** ***************************.******* ***:****************** **************:*********************:***.*******************:** * ** :** **.*:.****************************** : .:* **************.***.*:*::**********:**: .*****:****.* *:*.**.*: ....**:**************************:*****: *:*..*.* **.:*****.********** ****** * ***********. .* : .* :. .:. :********************************************************************************.***********************.:*.********************************************", "identical_positions": 724, "similar_positions": 147, "identity": "76.21%" }, { "cls_id": "homologset.agr.RGD:620752", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q12458-1", "uniprot_id": "YPR1_YEAST", "id": "Q12458-1", "name": "Aldehyde reductase YPR1", "aln": "-------------MPATLKNSSATLKLNTGASIPVLGFGTWRSVDNNG----YHSVIAALKAGYRHIDAAAIYLNEEEVGRAIKD----SGVPREEIFITTKLWGTEQRDP--EAALNKSLKRLGLDYVDLYLMHWPVPLKTDRVTDGNVLCIPTL------EDGTVDIDTKEWNFIKTWELMQELPKTG---KTKAVGVSNFSINNIKELLESPNNKVVPATNQIEIHPLLPQDELIAFCKE-KGIVVEAYSPFGSA------------NAPLLKEQAIIDMAKKHG-VEPAQLIISWSIQRGYVVLAKSVNPERIVSNFKIFT---LPEDDFKTISNLSKVHGTK---RVVDMKWGSFPIFQ--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P14065-1", "uniprot_id": "GCY1_YEAST", "id": "P14065-1", "name": "Glycerol 2-dehydrogenase (NADP(+))", "aln": "-------------MPATLHDSTKILSLNTGAQIPQIGLGTWQSKENDA----YKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKD----SGVPREEIFVTTKLWCTQHHEP--EVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTK------KDGSRAVDITNWNFIKTWELMQELPKTG---KTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKS-KGIVVEAYSPLGST------------DAPLLKEPVILEIAKKNN-VQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKIFT---LSTEDFEAINNISKEKGEK---RVVHPNWSPFEVFK--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8VCX1-1", "uniprot_id": "AK1D1_MOUSE", "id": "Q8VCX1-1", "name": "Aldo-keto reductase family 1 member D1", "aln": "---------------MNLSAAHHQISLSDGNNIPLIGLGTYSDPRPVP-GKTYVAVKTAIDEGYRHIDGAYVYHNEHEVGEAIREKIAEGKVKREEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYIIELPMAFK------PGKEIYPR--------DENGRIIYDKTNLCATWEALEACKDAG---LVKSLGVSNFNRRQLELILNKPGLKYKPVTNQVECHPYFTQTKLLKFCQQ-HDIVIVAHSPLGTC---RNPSWVNVSSPPLLNDELLTSLGKKYN-KTQAQIVLRFNIQRGIVVIPKSFTPERIKENFQIFD-FSLTEEEMKDIDALNKNVRYV--ELLMWSDHPEYPFHDEY------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31210-1", "uniprot_id": "AK1D1_RAT", "id": "P31210-1", "name": "Aldo-keto reductase family 1 member D1", "aln": "---------------MNLSTANHHIPLNDGNSIPIIGLGTYSDPRPVP-GKTFIAVKTAIDEGYRHIDGAYVYRNEHEVGEAIREKVAEGKVKREEIFYCGKLWSTDHDPEMVRPALERTLQTLKLDYIDLYIIEMPMAFK------PGEEFYPK--------DENGRVIYHKSNLCATWEALEACKDAG---LVKSLGVSNFNRRQLEVILNKPGLKYKPVTNQVECHPYFTQTKLLEVSASSMTSFIVAYSPLGTC---RNPLWVNVSSPPLLKDELLTSLGKKYN-KTQAQIVLRFDIQRGLVVIPKSTTPERIKENFQIFD-FSLTKEEMKDIEALNKNVRFV--EMLMWSDHPEYPFHDEY------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51857-1", "uniprot_id": "AK1D1_HUMAN", "id": "P51857-1", "name": "Aldo-keto reductase family 1 member D1", "aln": "---------------MDLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFK------PGDEIYPR--------DENGKWLYHKSNLCATWEAMEACKDAG---LVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQ-HDIVITAYSPLGTS---RNPIWVNVSSPPLLKDALLNSLGKRYN-KTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFD-FSLTEEEMKDIEALNKNVRFV--ELLMWRDHPEYPFHDEY------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38715-1", "uniprot_id": "GRE3_YEAST", "id": "P38715-1", "name": "NADPH-dependent aldose reductase GRE3", "aln": "--------------------MSSLVTLNNGLKMPLVGLGCWKIDKKVC----ANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYV----PFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEG---LIKSIGVSNFQGSLIQDLLR--GCRIKPVALQIEHHPYLTQEHLVEFCKL-HDIQVVAYSSFGPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQELKDISALNANIRFN--DPWTWLDG-KFPTFA--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VTY2-1", "uniprot_id": "Q9VTY2_DROME", "id": "Q9VTY2-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "------------------MKLAPTVKLNNGYEMPILGLGTYNSKDNEG----EAAVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAEGVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYV----DDNTLLPK--------NEDDVLQLSDVDYLDTYKAMEKLVKLG---LVRSIGVSNFNSEQLARVLAN--CEIKPVTNQVECSPALNQKALTAFCKK-NDVTLTGYTPLGKP-------KPDIQKPDFIYSPEVAVIAKKYG-KTTPQIVLRYLVGLGVIPIPKSSNTNRISENFDIFD-FELTAEEMAVLDGYHTGERVVPLNLIKGLNHKYYPFSIEF------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZK8-1", "uniprot_id": "Q9VZK8_DROME", "id": "Q9VZK8-1", "name": "NADP-dependent oxidoreductase domain-containing protein", "aln": "----------------MTGKVEYYFKHNDGTHIQGIGLGTFASTEGDC----ERAVLHAIDVGYRHIDTAYFYGNEAEVGAAVRKKIAEGVIKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYR----GDNELIPK--------DANGEVELVDIDYLDTWGAMEKLVDLG---LTKSIGVSNFNEEQLTRLLAN--CKIKPIHNQIEVHPALDQKKLIALCKK-NGILVTAFSPLGRH-------NAELRTPTFMYDGKVQAIADKYN-KSIAQVVIRYVIELGTIPLPKSSNPKRIEENFNVFD-FKLDAEDHAILDSYHNGERVA--HARQAIKSKYYPFNVYSACF---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38115-1", "uniprot_id": "ARA1_YEAST", "id": "P38115-1", "name": "D-arabinose dehydrogenase [NAD(P)+] heavy chain", "aln": "MSSSVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLA--ETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWP--VLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTP-----VDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKE--CRVKPTVNQVETHPHLPQMELRKFCFM-HDILLTAYSPLGSHG------------APNLKIPLVKKLAEKYN-VTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS---LTKDELQELNDFGEKYPVRFIDEPFAAILPEFTGNGPNLDNLKY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : :*:* : *:. *** :* * * .* ** .::. . : *:::* *:* . * : *:*:** . * . : . *: :: :::*****. : :: . * *:* * : * * .. : ..:.:* . : : :... .::: : * :.:* . *: . .. * :: :. : ", "identical_positions": 40, "similar_positions": 74, "identity": "10.75%" }, { "cls_id": "homologset.agr.RGD:620753", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35427-1", "uniprot_id": "RPC9_MOUSE", "id": "O35427-1", "name": "DNA-directed RNA polymerase III subunit RPC9", "aln": "MEVKDANAALLSNYEVFQLLTDLK------EQRKESGKNKHSAGQQN-------LNAITYETLKYISKTP------------------------CRNQSPAIVQEFLTAMKSHKLTKAEKLQLLNHRPMTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAGPEDEQSKSTSNDVAMEEEEPA-------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VHM6-1", "uniprot_id": "RPC9_RAT", "id": "Q8VHM6-1", "name": "DNA-directed RNA polymerase III subunit RPC9", "aln": "MEVKDANAALLSNYEVFQLLTDLK------EQRKESGKNKHSAGQQN-------LNAITYETLKYISKTP------------------------CKNQSPAIVQEFLTAMKSHKLTKAEKLQLLNHRPMTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAGPEDEQSKSTSNDAAMEEEEPA-------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75575-1", "uniprot_id": "RPC9_HUMAN", "id": "O75575-1", "name": "DNA-directed RNA polymerase III subunit RPC9", "aln": "MEVKDANSALLSNYEVFQLLTDLK------EQRKESGKNKHSSGQQN-------LNTITYETLKYISKTP------------------------CRHQSPEIVREFLTALKSHKLTKAEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAEPEAEQKKNTNSNVAMDEEDPA-------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NAV1-1", "uniprot_id": "A0A8M1NAV1_DANRE", "id": "A0A8M1NAV1-1", "name": "DNA-directed RNA polymerase III subunit RPC9", "aln": "MEVRDANAAMLSNYEVYQLLTDLK------EKRKEMVKNKHSTGQQN-------LNTIMYETLKYLSKTP------------------------CVHQKPETVKEFLTAMLPHKLTKAEKLQLLNHRPQTAVEIQLMVEESEERLTEEQIDELIQKVTDILPGDPQTEAN--ESADPQMDTNQ---------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47076-1", "uniprot_id": "RPC9_YEAST", "id": "P47076-1", "name": "DNA-directed RNA polymerase III subunit RPC9", "aln": "MKVLEERNAFLSDYEVLKFLTDLEKKHLWDQKSLAALKKSRSKGKQNRPYNHPELQGITRNVVNYLSINKNFINQEDEGEERESSGAKDAEKSGISKMSDESFAELMTKLNSFKLFKAEKLQIVNQLPANMVHLYSIVEECDARFDEKTIEEMLEIISGYA-------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VX99-1", "uniprot_id": "Q9VX99_DROME", "id": "Q9VX99-1", "name": "DNA-directed RNA polymerase III subunit RPC9", "aln": "METINPTFSYLTNLEVMQILQKIK-------------STKKKFGMRN-------LATVTYEALQYLEESP------------------------CKTQTRENIMNYVKDLSSYRLKSQEILQMINDPPTSALHTQLLIDDNKAPLTDEENEKIIQLSYKHFHGGETKGAAKETPAEKPAESTAKAGKQSGVKRNAQAKSNPAEQIAPADKTTPGDGVTPANVATPSSEATTTTPAEEASPVETSSSENNATPANEATTAPATDAPTSMETKSNPTPDGENLG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. : : *:: ** ::* .:: ...:. * :* * : :.::*:. . . . : :. : ..:* . * **::*. * . :. :::: . : :: : ::. ", "identical_positions": 15, "similar_positions": 53, "identity": "5.32%" }, { "cls_id": "homologset.agr.RGD:620754", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HP6-1", "uniprot_id": "SPAT2_RAT", "id": "Q66HP6-1", "name": "Spermatogenesis-associated protein 2", "aln": "------MDTKYKDDLFRKYVQ-----FHEGKVDTTPG-KQSGSDEYLRVAAATLLSLHKVDPLYRFRLIQFYEVVESSLRSLSSSSLSALHCAFSMLETMAINLFLFPWKKEFRSIKTYTGPFVYYVKSTLLEKDIRAILKFMGYEPELGTAYKLKELV-ESLQVKMVSFELFLAKVECEQMLGIHS----------------------------------QVKDKGYSELDVVTERKSSTEDARGCSDALRRRAESREHLTTSMARVALQKSASERAAKDYYKPRVTKP------------SRSVDAYDS---YWESRKPPSKASLSLRKEPLAMDVGEDLKDEIIRPSPSLLTMSSSPHGSPDDLPSISP-INGL-GLLRS---TYFPTQDDVDLYTDSEP--RATYRRQDALRS-DIWLVKNDAHSIYHKRSPPTKESALSKCQNCGLSCSSS------------------------------LCQRCDS--VCPSASKPS-------GFPS-KASAHDSLVHGAPMR-----------------------------EKYVG-QTQGLDRLAT-------------------VHSKPKPS-----TTATS-------------RCGFCNRAG-------------------------------ATNTCTQCSKVSCDPCLGAYHYDPCCRKSELHKFMPNNQ--------------------------------------------------------LNYKSTQFSHPVYR----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K004-1", "uniprot_id": "SPAT2_MOUSE", "id": "Q8K004-1", "name": "Spermatogenesis-associated protein 2", "aln": "------MDTKYKDDLFRKYVQ-----FHEGKVDTTPGNQQPGSDEYLRVAAATLLSLHKVDPLYRFRLIQFYEVVESSLRSLSSSSLSALHCAFSMLETMAINLFLFPWKKEFRSIKTYTGPFVYYVKSTLLEKDIRAILRFMGYEPELGTVYKLKELV-ESLQVKMVSFELFLAKVECEQMLGIHS----------------------------------QVKDKGYSELDVVAERKGSTEDARGCSDALRRRAESREHLTTSMARVALQKSASERAAKDYYKPRVTKP------------SRSVDAYDS---YWESRKPPSKASLSLRKEPLAMDVGEDLKDEIIRPSPSLLAMSSSPHGSPDDLSSISS-INGL-GLLRS---TYFSTQDDVDLYTDSEP--RATYRRQDALRP-DVWLVKNDTHPIYHKRSPPTKESALSKCQNCGLSCSSS------------------------------LCQRCDSVLVCPSASKPS-------AFPS-KASVHDSLAHGAPMR-----------------------------EKYVGHQTQGLDRLAP-------------------VHSKPKPS-----TTATS-------------RCGFCNRAG-------------------------------ATNTCTQCSKVSCDACLGAYHYDPCCRKSELHKFLPNSQ--------------------------------------------------------LNYKSAPFSQLVYR----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UM82-1", "uniprot_id": "SPAT2_HUMAN", "id": "Q9UM82-1", "name": "Spermatogenesis-associated protein 2", "aln": "MGKPSSMDTKFKDDLFRKYVQ-----FHESKVDTTTSRQRPGSDECLRVAASTLLSLHKVDPFYRFRLIQFYEVVESSLRSLSSSSLRALHGAFSMLETVGINLFLYPWKKEFRSIKTYTGPFVYYVKSTLLEEDIRAILSCMGYTPELGTAYKLRELV-ETLQVKMVSFELFLAKVECEQMLEIHS----------------------------------QVKDKGYSELDIVSERKSSAEDVRGCSDALRRRAEGREHLTASMSRVALQKSASERAAKDYYKPRVTKP------------SRSVDAYDS---YWESRKPPLKASLSLRKEPVATDVGDDLKDEIIRPSPSLLTMASSPHGSPDVLPPASP-SNGP-ALLRG---TYFSTQDDVDLYTDSEP--RATYRRQDALRP-DVWLLRNDAHSLYHKRSPPAKESALSKCQSCGLSCSSS------------------------------LCQRCDSLLTCPPASKPS-------AFPS-KASTHDSLAHGASLR-----------------------------EKYPG-QTQGLDRLPH-------------------LHSKSKPS-----TTPTS-------------RCGFCNRPG-------------------------------ATNTCTQCSKVSCDACLSAYHYDPCYKKSELHKFMPNNQ--------------------------------------------------------LNYKSTQLSHLVYR----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QCY8-1", "uniprot_id": "SPAT2_DANRE", "id": "F1QCY8-1", "name": "Spermatogenesis-associated protein 2", "aln": "------MDAKLREDLFRRYVASLENRLEEGAAEGGGDRQGAKTEEALISTATALLGSYQADPGQRFRMLRFYDVVENSLRTQRGTSLRTVGTAFATLETICTNLLLFPWKKEYRCIKTFTGPYVYQLQSVLCDSDLRSLLRSMGYSREQELQYNVRDHPGGASHLRQLAFELLLAQAECRLLGEVVS----------------------------------MSRG-FASELEAVELRRNTREDAAGCADALRR----RDSLTGDLSRLSVRPLDIDRAHLR----RSGRP------------SKSVDVTDSAGHWHQASKPVLKASLSLRKEPLFVDTEEDMKDEIIRPSPSLYPVAAPPSYSP--VADFFP-IQSPPSEPYS---YHLSSLDEVDLYTERGLGGHQTPSRPPSREPRDSWVLKG--HMMKCQGCG-MGCPSLSSCQRCDMILCSSCHAVDPAPCCGFQD---YTKTSRPLDGYMPIKEKLSVYSSAHSHTHPH-------PHPLPHAQSHSLLLDKAVMS-----------------------------SKLFPSKPVGSGPSPVGSL----------------VSSGSSSSGGERLSVGGS-------------RCGFCNKPG-------------------------------ASHTCVNCSKVSCDTCMSLYASDLCTRKNPHHNFVPNHQ--------------------------------------------------------LNFKSSTISHLVYR----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1A4-1", "uniprot_id": "TAMO_DROME", "id": "Q9W1A4-1", "name": "Protein tamozhennic", "aln": "--MSDFVPHDLIPDLWDEILR-----RHWMFLETEESIEKLEERKQLEGCLKEFLCVVQHDR--KFFLPETGHVLRRSVLELPDFSAQNAIVAFETISQYANNLFTKPWRKEYRTLKTYSGCFQHDIQSRLLDAEQ--LFLAMGYRRAAEDTFVLEGPI-CPDQVTNVSRDAMAAYVECQIMKHIYAGVTAAGYVCTWKDILQFRERYVGGTSTTIKEMVRQLSEKRVRMEQPPMQENTYSNVVSAAPTACGMRSNNVAHHPSSSGTCALHPNGLNEAGKYLPPYPAPPPQQPHLPGPLMTHSRSLDHYQEPQAHLPHRHSFDQQLQQQCQLPHVYEAPYDCLDGLSMGSSASYAAVTGAYNAPGNRYPLPYNISSQLNAPYASPADFYGNGQHTNMYATLGKTGPAHSCDLHRRQPNTSAAAAAALAAMQHRQSTYPPDHHLIDFDERAHLTQHDFGTHDYDPQYAELRGQVQPSMRGNPVAMYATYGGYDLPTTLPQAPPPTGQDMYIYARPVPKSSRMRALAEAGGINSTDKHPRSAEKQSTMDNNRKMHKELKERNSRTAPAKRSGTERDIPTTISDLNSYDSASLDGFVALDSSSSPPLMPKVQEGVGSFESWNYVFKNLERSGYTKDLGDREDLLVQSLDLGSLSITNGGAAPPAEKRREATNPTNGEKARTLDKKSGTGRREAKVVQAPAPSPLPNSSSAGVKKVKSALKTAVVDNRGTGSRQRTGAVPKQPPNVSPQLIVTSPNEWSCSFCTFLNPDTKRICEMCCRSKDFNLEAASAASSSAAAAAASAASVSHASSTCV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . **: . : . : . : : * :* : * :* : . .*:. *: . * ** :. **: **:**:* :**::* : : ::* * : : :: *** : :. . :: :: : : * .**. : : : : .. : . ... * . . . ::: :.* * *:*:* :. :. : . : * :. * * : *.: . : . :* .. . . . :..::*: .. : : . * . : . . . * * ::. * . . : .: : * : * .... . *.*: : * *::. . : * . : : . :** . ** .: :.. * ", "identical_positions": 57, "similar_positions": 140, "identity": "7.05%" }, { "cls_id": "homologset.agr.RGD:620755", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35876-1", "uniprot_id": "SMN_RAT", "id": "O35876-1", "name": "Survival motor neuron protein", "aln": "MAMGSGGGAG--SEQEDTVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKN--GDMCETSDKPKGTARRKPAKKNKNQKKNATAPLKQWKAGDKCSAVWSEDGCVYPATITSVDLKRETCVVVYTGYGNKEEQNLSDLLSPTCEVANNTEQNTQENE--SQVSTDDSEHSSRSLRSKAHSKSKAAPWTSFLPPPPPVPGAGLGPGKPGLRFSGPPPPPP-PPPPFLPCWMPPFPSGPPIIPPPPPISPDCLDDTDALGSMLISWYMSGYHTGYYMGFRQNKKEGKKCSHTN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97801-1", "uniprot_id": "SMN_MOUSE", "id": "P97801-1", "name": "Survival motor neuron protein", "aln": "MAMGSGG-AG--SEQEDTVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKN--GDICETPDKPKGTARRKPAKKNKSQKKNATTPLKQWKVGDKCSAVWSEDGCIYPATITSIDFKRETCVVVYTGYGNREEQNLSDLLSPTCEVANSTEQNTQENE--SQVSTDDSEHSSRSLRSKAHSKSKAAPWTSFLPPPPPMPGSGLGPGKPGLKFNGPPPPPPLPPPPFLPCWMPPFPSGPPIIPPPPPISPDCLDDTDALGSMLISWYMSGYHTGYYMGFRQNKKEGK-CSHTN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16637-1", "uniprot_id": "SMN_HUMAN", "id": "Q16637-1", "name": "Survival motor neuron protein", "aln": "MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKN--GDICETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGR-CSHSLN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W6S8-1", "uniprot_id": "SMN1_DANRE", "id": "Q9W6S8-1", "name": "Survival motor neuron protein 1", "aln": "--MANGA---------EDVVFCRGTGQSDDSDIWDDTALIKAYDKAVASFKNALKG--EDGATPQENDNPGKKRKNNKKNKSRKRCNAAPDKEWQVGDSCYAFWSEDGNLYTATITSVDQEKGTCVVFYTDYGNEEEQNLSDLLTEPPDMDEDALKTANVKE--TESSTEESDRSFTP-QKSGHAKHKSK-SNFPMGPPSWFPSFPPGPPPPPPHFKKMDGRRGEGPGPSFPGWPPMIPLGPPMIPPPPPMSPDFGEDDEALGSMLISWYMSGYHTGYYMGLRQGRKEAAASKKSHRK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV74-1", "uniprot_id": "SMN_DROME", "id": "Q9VV74-1", "name": "Survival motor neuron protein", "aln": "------------------------MSDETNAAVWDDSLLVKTYDESVGLAREALARRLADSTNKREEENAAAAEEEAGEISATGGATSPEPVSFKVGDYARATY-VDGVDYEGAVVSINEEKGTCVLRYLGYENEQEVLLVDLLPSWGKRVRREQFLIAKKD-------EDEQLSRPKASAGSHSKTPKSSRRSRISGGLVMP---------------------------------------PMPPVPPMIVGQGDGAEQDFVAMLTAWYMSGYYTGLYQGKKEASTTSGKKKTPKK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. :: :***: *:*:**::*. :.** * : : .: : . :. .::.** . * : ** * .::.*:: :: ***: * .* *.:* * ***. . . :: ::.: * : * : .* *: * ** : : : : :** :******:** * * :: . . . . ", "identical_positions": 48, "similar_positions": 66, "identity": "16.11%" }, { "cls_id": "homologset.agr.RGD:620756", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M6T6-1", "uniprot_id": "A0ABK0M6T6_RAT", "id": "A0ABK0M6T6-1", "name": "Cold-inducible RNA-binding protein", "aln": "MRPEHIPANQNTQRLRAGNGEANGVPPLHPGTAAESEASDWSARHAGRAQRRGSRGGVYQAGLRRSPSHSRVRKLGCVTRCLPARVRDLPDSAAAMASDEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGS-AGGRGFFRGGRSRG-------------RGF----------SRGGGDRGYGGGR--FESRSGGYGGSRDYYASRS----QGGSY-------GYRSSGGSYRDSYDSYG----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60824-1", "uniprot_id": "CIRBP_MOUSE", "id": "P60824-1", "name": "Cold-inducible RNA-binding protein", "aln": "-----------------------------------------------------------------------------------------------MASDEGKLFVGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGS-AGGRGFFRGGRSRG-------------RGF----------SRGGGDRGYGGGR--FESRSGGYGGSRDYYASRS----QGGSY-------GYRSSGGSYRDSYDSYATHNE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14011-1", "uniprot_id": "CIRBP_HUMAN", "id": "Q14011-1", "name": "Cold-inducible RNA-binding protein", "aln": "-----------------------------------------------------------------------------------------------MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGS-AGGRGFFRGGRGRG-------------RGF----------SRGGGDRGYGGNR--FESRSGGYGGSRDYYSSRS----QSGGY-------SDRSSGGSYRDSYDSYATHNE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N8U3-1", "uniprot_id": "A0A8M1N8U3_DANRE", "id": "A0A8M1N8U3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------MSDEGKLFIGGLSYDTTEQSLEEAFSKYGTIAKVDVIRDRETDRSRGFGFVTFENPEDAKDAMAAMNGKQVDGRMIRVDEAGKSG-GRSGGFRGGSRGGGRGFFRGSRGRGGGGYGGDRSYGSDRSFGGDRSYGGDRSYGGGDRGYGGGERSYGGGDRSYGGGGGGYSNRSGGYSSGGGYRDNRNQGGYDRSGGSYRDGYDSYASHE-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:****:**.**:**:.***** *::* *::****:************ :****** *****.**** ****:****. .** *:**** .********.*.** *.* * *********.. : . . .***. . *:.** ..*.* . *******.****. ", "identical_positions": 113, "similar_positions": 37, "identity": "37.17%" }, { "cls_id": "homologset.agr.RGD:620757", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88177-1", "uniprot_id": "PEX12_RAT", "id": "O88177-1", "name": "Peroxisome assembly protein 12", "aln": "--------MAEHGAHITTASVADDQ------PSIFEVVAQDSLMTAVRPALQHVVK-VLAESNPAHYGFFW-RWFDEIFTLLDFLLQQHYLSRTSASFSEHFYGLKRIVAGS---------SPQLQRPASAGLPKEHLWKSAMFLV--LLPYLKVKLEKLASTLREEDEYSIHPPSSHWKRFYRVFLAAYPFVTMTWEGWFLTQQLRYILGKAEHHSP---LLKLAGVRLGRLTAQDIQAMEHRLVEASAMQEPVRSIGKKIKSALKKAVGGVALSLSTGLSVGVFFLQFLDWWYSSENQETIKS-LTALPTPPPPVHLDYNSDSPLLPK-MKTVCPLCRKARVNDTVLATSGYVFCYRCVFNYVR-SHQACPIT-------GYPTEVQHLIKLYSPEN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC48-1", "uniprot_id": "PEX12_MOUSE", "id": "Q8VC48-1", "name": "Peroxisome assembly protein 12", "aln": "--------MAEYGAHITTASVADDQ------PSIFEVVAQDSLMTAVRPALQHVVK-VLAESNPAHYGFLW-RWFDEIFTLLDFLLQQHYLSRTSASFSEHFYGLKRIVAGS---------SPHLQRPASAGLPKEHLWKSAMFLV--LLPYLKVKLEKLASSLREEDEYSIHPPSSRWKRFYRAFLAAYPFVNMAWEGWFLTQQLRYILGKAEHHSP---LLKLAGVRLARLTAQDMQAIKQRLVEASAMQEPVRSVGEKIKSALKKAVGGVALSLSTGLSVGVFFLQFLDWWYSSENQEAIKS-LTALPTPPPPVHLDYNSDSPLLPK-MKTVCPLCRKTRVNDTVLATSGYVFCYRCVFNYVR-SHQACPIT-------GYPTEVQHLIKLYSPEN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00623-1", "uniprot_id": "PEX12_HUMAN", "id": "O00623-1", "name": "Peroxisome assembly protein 12", "aln": "--------MAEHGAHFTAASVADDQ------PSIFEVVAQDSLMTAVRPALQHVVK-VLAESNPTHYGFLW-RWFDEIFTLLDLLLQQHYLSRTSASFSENFYGLKRIVMGD---------THKSQRLASAGLPKQQLWKSIMFLV--LLPYLKVKLEKLVSSLREEDEYSIHPPSSRWKRFYRAFLAAYPFVNMAWEGWFLVQQLRYILGKAQHHSP---LLRLAGVQLGRLTVQDIQALEHKPAKASMMQQPARSVSEKINSALKKAVGGVALSLSTGLSVGVFFLQFLDWWYSSENQETIKS-LTALPTPPPPVHLDYNSDSPLLPK-MKTVCPLCRKTRVNDTVLATSGYVFCYRCVFHYVR-SHQACPIT-------GYPTEVQHLIKLYSPEN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPT5-1", "uniprot_id": "PEX12_DROME", "id": "Q9VPT5-1", "name": "Peroxisome assembly protein 12", "aln": "-----------MAEAANVRQNLQNV------PSIFEISASETLDNLIYPALSKIFD-YFGLRLDFKLWGSL-RIQEELSPLLTWLLQYLYLRKRASSFGESFYGLQRTVTTT---------GDLLNR--------RQQFASATLLT--FMPYVERKLR---------TRITRHEDTSPWEQRLLSAFHAFHAAKAAHT-------FFYLVKYASNHSP---IFRLLGLTLR-------------------------------YPSEPPKEDQWTYVVLKMLEVLAFFLQFVQWWYSNDQRRKVGG-TLINPEAMPRKQLPKEVQQSLP---QRGECPVCLLSIQTPTACSVSGYVFCWKCIVSHMK-EHGTCPVT-------HYPISLDDLVRIYET-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04370-1", "uniprot_id": "PEX12_YEAST", "id": "Q04370-1", "name": "Peroxisome assembly protein 12", "aln": "MSFYSNLPSAGQSSRGSSTSGRNGVGLEPLYPTIFEIMSSQEIDSLLPASIRYLLANHLVANFPNRYTLRLNKYFFEWFQAIKGFVEWYHLKTYNSTFIDRFYGLQLFSSRDRNLALTQCLNPKGQSEWPQGLQLNQQQKSVIFLEKIILPYITAKLDEILEKISMNNIFSSDETENKWPKR--AFLRIYPFIKKLLALSNLLVKLLFLTKRTGSVSLLQYLFKIEYTTVRPLSSELSGLKETKGMDNRLRKTNISSIFALMQGQLSIIPRFLTFMGSQFFPTFIFVLRVYQWWTTQDMTTKLQKRVNDLDEDIPRPPFSSHSDKTEDKEGVSEACPVCEKTVQNPCVLET-GYVACYPCAISYLVNNEGHCPVTNKKLLGCTYNKHTNKWEVVTGIRKLLI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . :. *:***: :.: : . : .:: :. : : : * : ::: :* ::* : ****: : .: * :* ::**: ** : . . * : : : . : :: : * :::: : : : . *.*:. :** :.: : * : . :.. **:* : . . . *** *: * . :: .. **:* * :. : ", "identical_positions": 36, "similar_positions": 84, "identity": "8.96%" }, { "cls_id": "homologset.agr.RGD:620759", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62881-1", "uniprot_id": "GNB5_MOUSE", "id": "P62881-1", "name": "Guanine nucleotide-binding protein subunit beta-5", "aln": "MCDQTFLVNVFGSCDKCFKQRALRPVFKKSQQLNYCSTCAEIMATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALG--QFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAM-HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS----ETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYS---------------KESIIF--------------------GASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14775-1", "uniprot_id": "GNB5_HUMAN", "id": "O14775-1", "name": "Guanine nucleotide-binding protein subunit beta-5", "aln": "MCDQTFLVNVFGSCDKCFKQRALRPVFKKSQQLSYCSTCAEIMATEGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALG--QFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAM-HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS----ETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYS---------------KESIIF--------------------GASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62882-1", "uniprot_id": "GNB5_RAT", "id": "P62882-1", "name": "Guanine nucleotide-binding protein subunit beta-5", "aln": "------------------------------------------MATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALG--QFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAM-HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPS----ETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYS---------------KESIIF--------------------GASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1L271-1", "uniprot_id": "GNB5A_DANRE", "id": "A1L271-1", "name": "Guanine nucleotide-binding protein subunit beta-5a", "aln": "----------------------------------------MAAQEEPAQPGDSLATLKSESDTLKSKLEEERAKLHDVELHQVAEKIEALG--QFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDAFTTNKEHAVTMPCTWVMACAYAPSGCAVACGGLDNKCSVYPLSLDKNENLAAKKKSVAM-HTNYLSACCFTNSDMQILTSSGDGTCALWDVESGQMLQSFHGHAADVLCLDLAPS----ETGNTFVSGGCDKKACVWDMRTGQCVQSFESHDSDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYS---------------KESIIF--------------------GASSVDFSLSGRLLFGGYNDYTINVWDVLKGARVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRIWA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PBY0-1", "uniprot_id": "GNB5B_DANRE", "id": "Q6PBY0-1", "name": "Guanine nucleotide-binding protein subunit beta-5b", "aln": "MCDQTFLAITFGPCDKCSENKPLMNIYLKNEPINYCSLCVEMMACQGLAKGETVQSLKAESESLKAKLEEERAKLHDVELHQVAEKMEALG--QFVMKTRRTLKGHGNKVLCMDWCRDKRRIVSSSQDGKVIVWDAYTTNKEHAVTMPCTWVMACAYAPSGCAVACGGLDNKCSVYPLSLDKNENLASKKKSVAM-HTNYLSSCSFTKSDMQILTSSGDGTCALWDVESGQLLQSFHGHSADVLSLDLAPS----ETGSTFVSGGCDKKANVWDMRSGQNVQSFETHDSDINSVKYYPSGDAFASGSDDATCRLYDLRADREVAIYS---------------KDSIIF--------------------GASSVDFSLSGRLLFAGYNDYNINVWDVLKGTRVAILFGHENRVSTVRVSPDGTAFCSGSWDNTLRIWA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3J1-1", "uniprot_id": "Q9W3J1_DROME", "id": "Q9W3J1-1", "name": "", "aln": "-----------------------------------MSEAAVPASNANANATEKMASLVREAENLKTKLEEERQKLNDVNLSNIAERLEQIA--YVNIKPRKVLKGHQAKVLCTDWSPDKRHIISSSQDGRLIIWDAFTTNKEHAVTMPTTWIMACAYAPSGNFVACGGLDNKVTVYPITSD--EEMAAKKRTVGT-HTSYMSCCIYPNSDQQILTGSGDSTCALWDVESGQLLQSFHGHSGDVMAIDLAPN----ETGNTFVSGSCDRMAFIWDMRSGHVVQSFEGHQSDVNSVKFHPCGDAIATGSDDSSCRLYDMRADREVAVFA---------------KESIIF--------------------GVNSVDFSVSGRLLFAGYNDYTVNLWDTLKSERVCLLYGHENKVSCVQVSPDGTALSTGSWDYTIRVWA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P18851-1", "uniprot_id": "GBB_YEAST", "id": "P18851-1", "name": "Guanine nucleotide-binding protein subunit beta", "aln": "---------------MAAHQMDSITYSNNVTQQYIQPQSLQDISAVEDEIQNKIEAARQESKQLHAQINKAKHKIQDASLFQMANKVTSLTKNKINLKPNIVLKGHNNKISDFRWSRDSKRILSASQDGFMLIWDSASGLKQNAIPLDSQWVLSCAISPSSTLVASAGLNNNCTIYRVSKE--NRVAQNVASIFKGHTCYISDIEFTDN-AHILTASGDMTCALWDIPKAKRVREYSDHLGDVLALAIPEEPNSENSSNTFASCGSDGYTYIWDSRSPSAVQSFYVNDSDINALRFFKDGMSIVAGSDNGAINMYDLRSDCSIATFSLFRGYEERTPTPTYMAANMEYNTAQSPQTLKSTSSSYLDNQGVVSLDFSASGRLMYSCYTDIGCVVWDVLKGEIVGKLEGHGGRVTGVRSSPDGLAVCTGSWDSTMKIWSPGYQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: : *:. *: :::: : *::*..* ::*::: : . :*.. .**** *: *. *.::*:*:**** :::**: : *::*:.: *:::** :**. :*..**:*: ::* :: : :.:* : :: ** *:* :... :***.*** ******: ..: ::.: .* .**:.: :. . ::..**.* ..* : :** *: **:* ::**:*::::. * ::.:***:.: .:**:*:* .:* :: .: : *. *:*** ****::. *.* :**.**. * * ** .:*: :: **** *..:**** *:::*: ", "identical_positions": 107, "similar_positions": 146, "identity": "24.26%" }, { "cls_id": "homologset.agr.RGD:62076", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M2N1-1", "uniprot_id": "A0ABK0M2N1_RAT", "id": "A0ABK0M2N1-1", "name": "Prostaglandin E synthase", "aln": "-------------MTSLGLVMENSQVLPAFLLCSTLLVIKMYAVAVITGQVRLRKKV--------RALAFANPEDALKRGGLQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPLIAWIHFLVVLTGRVVHTVAYLGK-MNPRIRSGAYVLAQFACFSMALQILWEVAHHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JM51-1", "uniprot_id": "PTGES_MOUSE", "id": "Q9JM51-1", "name": "Prostaglandin E synthase", "aln": "-------------MPSPGLVMESGQVLPAFLLCSTLLVIKMYAVAVITGQMRLRKK------------AFANPEDALKRGGLQYYRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPLIAWIHFLVVLTGRVVHTVAYLGK-LNPRLRSGAYVLAQFSCFSMALQILWEVAHHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14684-1", "uniprot_id": "PTGES_HUMAN", "id": "O14684-1", "name": "Prostaglandin E synthase", "aln": "-------------MPAHSLVMSS-PALPAFLLCSTLLVIKMYVVAIITGQVRLRKK------------AFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGK-LRAPIRSVTYTLAQLPCASMALQILWEAARHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5IHX7-1", "uniprot_id": "Q5IHX7_DANRE", "id": "Q5IHX7-1", "name": "Prostaglandin E synthase", "aln": "--------------------MLGSDIQLCFIFYSTLLILKMYIIAIITGQVRLRKK------------AFANPEDAERHGGVQFCRTDPYVERCRRAQQNDMENILPFLFLGAVYSMTSPSYAAAQLHFLIFFLGRVLHSVAYLLA-LKAPTRSLAYVIAQVPCISMAIQILMEVASFA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86B54-1", "uniprot_id": "Q86B54_DROME", "id": "Q86B54-1", "name": "Microsomal glutathione S-transferase 1", "aln": "MDNGPMDATPTAAAFRLILLSKSNPVMGCYMFWTSLLVLKMLVMSLLTARQR------------MKTKTYANPEDLRLSRSTEVRFGDPNVERVRRAHRNDLENILPFLLMSLAYVASGPNPLTARLLIRIGASARLIHTVVYAIIPVPQPARALAFFTTFAITCFEAGYVLVCCIKYI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "X2JF29-1", "uniprot_id": "X2JF29_DROME", "id": "X2JF29-1", "name": "Microsomal glutathione S-transferase 1", "aln": "MSAAASNSSKMMTSP-GDMFTLENPVFCCYLFWSTVLVVKMLLMSLLTAVQRFRYKLLAIVPLALRRRIFPNQEDL-FFKNLEVQFDDPHVERVRRAHRNDMENILPYFIMSLIYISTNPNADVACILFRVASVARIIHTLVYAVYPVPQPSRILAFATMLLITFYMAAVVALRTLSFI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::: :::*::** ::::*. * :.* ** . : ** *** **::**:*.* *::::. * .*. * : : : .*: *::.* : * :: * : . ", "identical_positions": 28, "similar_positions": 42, "identity": "15.64%" }, { "cls_id": "homologset.agr.RGD:620760", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53351-1", "uniprot_id": "PLK2_MOUSE", "id": "P53351-1", "name": "Serine/threonine-protein kinase PLK2", "aln": "--MELLRTIT-----YQPAAGTKMCEQALGKACGGDSKKKRPQQPSEDGQP---QAQVTPAAPHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLN--KQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMP--SSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPAKN--FFKKAAAALFGGKKDKARYNDTHNKVSKEDE--DIYKLRHDLKKVSITQQPSKHRADE-EPQPPPTTVARSGTSAVENKQQIGDAIRMIVRGTLGSCSSSS-ECLEDSTMGSVADTVARVLRGCLENMPEADCIPKEQLS--TSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKKTVHYYAELG----QCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRLYLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICNQSEEYLLTYINEDRISTTFRLTTLLMSGCS-----LELKNRMEYALNMLLQRCN----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R012-1", "uniprot_id": "PLK2_RAT", "id": "Q9R012-1", "name": "Serine/threonine-protein kinase PLK2", "aln": "--MELLRTIT-----YQPAAGTKMCEQALGKACGGDSKKKRPQQPSEDGQS---QAQVTPAAPHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLN--KQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMP--SSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPAKN--FFKKAAAALFGGKKDKARYNDTHNKVSKEDE--DIYKLRHDLKKTSITQQPSKHRTDE-ELQPPPTTFAKSGTSAVENKQQIGDAIRMIVRGTLGSCSSSS-ECLEDSTMGSVADTVARVLRGCLENMPEADCIPKEQLS--TSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKKTVHYYAELG----QCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRLYLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICNQNEEYLLTYINEDRISTTFRLTTLLMSGCS-----LELKHRMEYALNMLLQRCN----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NYY3-1", "uniprot_id": "PLK2_HUMAN", "id": "Q9NYY3-1", "name": "Serine/threonine-protein kinase PLK2", "aln": "--MELLRTIT-----YQPAASTKMCEQALGKGCGADSKKKRPPQPPEESQPPQSQAQVPPAAPHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLN--KQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMP--SSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPAKN--FFKKAAAALFGGKKDKARYIDTHNRVSKEDE--DIYKLRHDLKKTSITQQPSKHRTDE-ELQPPTTTVARSGTPAVENKQQIGDAIRMIVRGTLGSCSSSS-ECLEDSTMGSVADTVARVLRGCLENMPEADCIPKEQLS--TSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKKTVHYYAELG----QCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRLYLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYINEDRISTTFRLTTLLMSGCS-----SELKNRMEYALNMLLQRCN----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RNL4-1", "uniprot_id": "A0A8M1RNL4_DANRE", "id": "A0A8M1RNL4-1", "name": "Serine/threonine-protein kinase PLK", "aln": "--MDILRTIAHHHHHHQPVNSGKMCEHTHSRAS--ESRRRK------------------------LEDTSYATQEMSRIVTDSATGKCYCRGKVLGKGGFAKCYEFTDLSTGKMYAAKIIPHTRVSKPHQREKIDREIELHRALHHKHIVQFYHHFEDKDNIYILLEYCSRRSLAHILKARKVLTEPEVRYYLKQIVSGLKYLHEQEILHRDLKLGNFFINEFMELKVGDFGLAAKLEPLENRRRTICGTPNYLSPEVLN--KQGHGCESDVWALGCVMYTMLLGRPPFETTNLKETYRCIREARYSTP--SSLSPQAKHLISSMLAKNPVDRPQLCDILRHDFFCQGFTPDRLSANCCHAAPDIHHTSPAKS--FFKKAAATLFGGKKDKAKYLETRNKPAKEEEEININRLCIDLRKTSVSPQPCRQTLENNKPSIPSAGKPAVLTKDASSKQHIRDSIRMIVRGTLRSCSSSSSECLENCTVGSVADTVARVLQGCLENMSEANNISKESMN--SSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGTHMSLLSDKKTVHYYAELG----QCSVFLTSEAPEQFVGQATILKYFAHYMEENLMDGGDLPNITDANKPRLYLLQWLKSDQALMMLFNDGTFQVNFYHDHTKIILCNHREEYLLTYINEERVSTTLRLSTLLASGCS-----ADLQSRMDYALNMLLQRCGDVTDGKSRML", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32562-1", "uniprot_id": "CDC5_YEAST", "id": "P32562-1", "name": "Cell cycle serine/threonine-protein kinase CDC5/MSD2", "aln": "MSLGPLKAIND----KQLNTRSKLVHTPIKGNTADLVGKENHFKQTKRLDP---NNDHHHQPAQKKKREKLSALCKTPPSLIKTRGKDYHRGHFLGEGGFARCFQIKDDS-GEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWFRGTFPPS-IPSTVMSEAPNFEDIPEEQSLVNFKDCMEKSLLLESMSSDKIQRQKRDYISSIKSSIDKLEEYHQNRPFLPHSLSPGGTKQKYKEVVDIEAQRRLNDLAREARIRRAQQAVLRKELIATSTNVIKSEISLRILASECHLTLNGIVEAEAQYKMGGLPKSRLPKIKHPMIVTKWVDYSNKHGFSYQLSTEDIGVLFNNGTTVLRLADAEEFWYISYDDREGWVASHYLLSEKPRELSRHLEVVDFFAKYMKANLSRVSTFG-REEYHKDDVFLRRYTRYKPFVMFELSDGTFQFNFKDHHKMAISDGGK---LVTYISPSHESTTYPLVEVLKYGEIPGYPESNFREKLTLIKEGLKQKSTIVTVD-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *::* * *: . . :.. . . : : : ** * **:.**:****:*:::.* : .:::*** :.:: : . : *:*: **::*: : * ::*** . ***..*:***** *.. *: .:** **********:: ** ..:**:*.:.::********:*::. :**:******* * ..*: ********::**** :.**. * *:*:** ::*::*:*:***:: ::: *. *: :: * ..: .* ** .:*: :* :**.* :*: : :* *.*. :.:. .*::. . :. **.. : :. .: : ::: .. .* :* :: .. :. : : . . : :* : : ::* * : *:. :. . : : :: * : . :.*. : . **********:**.**** . :*******: : *.* : . * : . .* : :: *.:: : ::.:*::**: ** . : : .: ::* :: : . :*: :.*****.** ..*. * . *:***. .: *** * :* * ::: :: : * *:. ", "identical_positions": 184, "similar_positions": 227, "identity": "25.45%" }, { "cls_id": "homologset.agr.RGD:620761", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R172-1", "uniprot_id": "NOTC3_RAT", "id": "Q9R172-1", "name": "Neurogenic locus notch homolog protein 3", "aln": "MGPGARGRRRRRRL----------MALPPPPPPMRALPLLLLLLAGLG--------AAAPPCLDGSPCANGGRCTHQQPSREAACLCLPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGVARFSCRCLR----------------------------------------GFRGPDCSLPDPCFSSPCAHGAPCSVGS-DGRYACACPPGYQGRNCRSDIDECRAGASCRHGGTCINTPGSFHCLCPLGYTGLLCENPIVPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPN-ACHNGGTCFNLLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTFCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHPCAHKPCS-HGVCHDAPGGFQCVCDPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFHCTCAPGFQGHQCEV---------------------------------------LSPCTPSLCEHGGHCESDPDQLTV-CSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGSFRCICHGGYTGPFCDQDIDDCDPNPCLNGGSCQDGVGSFSCSCLSGFAGPRCARDVDECLSSPCGPG-TCTDHVASFTCTCPPGYGGFHCETDLLDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGTHCQYKVDPCFSRPCLHGGICNPTHSGFECTCREGFTGNQCQNPVDWCSQAPCQNGGRCVQTG--AYCICPPEWSGPLCDIPSLPCTEAAAHMGVRLEQLCQAGGQCIDKDHSHYCVCPEGRMGSHCEQEVDPCTAQPCQHGGTCRGYMGGYVCECPTGYSGDSCEDDVDECASQPCQNGGSCIDLVAHYLCSCPPGTLGVLCEINEDDCGPGPSLDSGLRCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECRPGTCHAAHTRDCLQDPGGHFRCICLPGFTGPRCQTALFPCESQPCQHGGQCRPSLGRGGGLTFTCHCVQPFWGLRCERVARSCRELQCPVG-IPCQQTARGPRCACPPGLSGPSCRVSRASPSGATNTSCAATPCLHGGSCLPVQSVPFFRCVCAPGWGGPRCETPSA----------------APEVPEE-PRCPRAACQAKRGDQNCDRECNSPGCGWDGGDCSLNVDDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCYSGGRDRTCNPVYKKYCADHFADGRCDQGCNTEECGWDGLDCASEVP-ALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDARGQAMVFPYH---RPSPGSESRVRRELGPEVIGSVVMLEIDNRLCLKSAENDHCFPDAQSAADYLGALSAVERLDFPYPLRDVRGEPLEPPE---QSVPLLPLLVAGAVFLLVIFVLG--VMVARRKREHSTLWFPEGFALHKDIAAGHKGRREPVGQDALGMKNMTKGES-LMGEVATDWND--SECPEAKRLK---VEEPGMGAE-------------EPVDCRQWTQHHLVAADIRVAPAMALTPPQGDADADGMDVNVRGPDGFTPLMLASFCGGALEPMPAEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQ--------------------PSGPRSP---------------------------------------------------------------------------------------SGPHGLGPLLCPPGAFLPGLKAVQSGTKKSRRPPGKTGLG------------------------------------------------------------------------------PQGTRGRGKK----------------------------------LTLACPGPLADSSVTLSPVDSLDSPRPFGGPPASP------------------GGFPLEGPYAT-TATTVSLAQLGASRAGPLGRQPPGGCVLSLGLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGSQLLNPATPVSPHERPPPYLAAPG-------HGEEYPAAGTHS--------------------------SPTKARFLRVPSEH---PYLTPSPESPEHWASPSPPSLSDWSDSTPSPATAT--SATAAGALPAQPHPISVP-SLPQSQTQLGPQPEVTPKRQVMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61982-1", "uniprot_id": "NOTC3_MOUSE", "id": "Q61982-1", "name": "Neurogenic locus notch homolog protein 3", "aln": "MGLGARGRRRRRRL----------MALPPPPPPMRALP-LLLLLAGLG--------AAAPPCLDGSPCANGGRCTHQQPSLEAACLCLPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCLR----------------------------------------GFQGPDCSQPDPCVSRPCVHGAPCSVGP-DGRFACACPPGYQGQSCQSDIDECRSGTTCRHGGTCLNTPGSFRCQCPLGYTGLLCENPVVPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPN-ACHNGGTCFNLLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSMCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHPCAHKPCS-HGVCHDAPGGFRCVCEPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFRCTCAPGFQGHQCEV---------------------------------------LSPCTPSLCEHGGHCESDPDRLTV-CSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGNFRCICHRGYTGPFCDQDIDDCDPNPCLHGGSCQDGVGSFSCSCLDGFAGPRCARDVDECLSSPCGPG-TCTDHVASFTCACPPGYGGFHCEIDLPDCSPSSCFNGGTCVDGVSSFSCLCRPGYTGTHCQYEADPCFSRPCLHGGICNPTHPGFECTCREGFTGSQCQNPVDWCSQAPCQNGGRCVQTG--AYCICPPGWSGRLCDIQSLPCTEAAAQMGVRLEQLCQEGGKCIDKGRSHYCVCPEGRTGSHCEHEVDPCTAQPCQHGGTCRGYMGGYVCECPAGYAGDSCEDNIDECASQPCQNGGSCIDLVARYLCSCPPGTLGVLCEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECRPGACHAAHTRDCLQDPGGHFRCVCHPGFTGPRCQIALSPCESQPCQHGGQCRHSLGRGGGLTFTCHCVPPFWGLRCERVARSCRELQCPVG-IPCQQTARGPRCACPPGLSGPSCRVSRASPSGATNASCASAPCLHGGSCLPVQSVPFFRCVCAPGWGGPRCETPSA----------------APEVPEE-PRCPRAACQAKRGDQNCDRECNTPGCGWDGGDCSLNVDDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCYSGGRDRTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDCASEVP-ALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDARGQAMVFPYH---RPSPGSESRVRRELGPEVIGSVVMLEIDNRLCLQSAENDHCFPDAQSAADYLGALSAVERLDFPYPLRDVRGEPLEAPE---QSVPLLPLLVAGAVFLLIIFILG--VMVARRKREHSTLWFPEGFALHKDIAAGHKGRREPVGQDALGMKNMAKGES-LMGEVVTDLND--SECPEAKRLK---VEEPGMGAE-------------EPEDCRQWTQHHLVAADIRVAPATALTPPQGDADADGVDVNVRGPDGFTPLMLASFCGGALEPMPAEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHLANREITDHLDRLPRDVAQERLHQDIVRLLDQ--------------------PSGPRSP---------------------------------------------------------------------------------------SGPHGLGPLLCPPGAFLPGLKAVQSGTKKSRRPPGKTGLG------------------------------------------------------------------------------PQGTRGRGKK----------------------------------LTLACPGPLADSSVTLSPVDSLDSPRPFSGPPASP------------------GGFPLEGPYAT-TATAVSLAQLGASRAGPLGRQPPGGCVLSFGLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGPQLLNPGAPVSPQERPPPYLAAPG-------HGEEYPAAGTRS--------------------------SPTKARFLRVPSEH---PYLTPSPESPEHWASPSPPSLSDWSDSTPSPATAT--NATASGALPAQPHPISVP-SLPQSQTQLGPQPEVTPKRQVMA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UM47-1", "uniprot_id": "NOTC3_HUMAN", "id": "Q9UM47-1", "name": "Neurogenic locus notch homolog protein 3", "aln": "MGPGARGRRRRRRP----------MSPPPPPPPVRALP-LLLLLAGPG--------AAAPPCLDGSPCANGGRCT-QLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPR----------------------------------------GFRGPDCSLPDPCLSSPCAHGARCSVGP-DGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPN-ACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCS-HGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL---------------------------------------LSPCTPNPCEHGGRCESAPGQLPV-CSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTG--AYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVG-VPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAA----------------APEVSEE-PRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDCASEVP-ALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDAHGQAMVFPYH---RPSPGSEPRARRELAPEVIGSVVMLEIDNRLCLQSPENDHCFPDAQSAADYLGALSAVERLDFPYPLRDVRGEPLEPPE---PSVPLLPLLVAGAVLLLVILVLG--VMVARRKREHSTLWFPEGFSLHKDVASGHKGRREPVGQDALGMKNMAKGES-LMGEVATDWMD--TECPEAKRLK---VEEPGMGAE-------------EAVDCRQWTQHHLVAADIRVAPAMALTPPQGDADADGMDVNVRGPDGFTPLMLASFCGGALEPMPTEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQ--------------------PSGPRSP---------------------------------------------------------------------------------------PGPHGLGPLLCPPGAFLPGLKAAQSGSKKSRRPPGKAGLG------------------------------------------------------------------------------PQGPRGRGKK----------------------------------LTLACPGPLADSSVTLSPVDSLDSPRPFGGPPASP------------------GGFPLEGPYAAATATAVSLAQLGGPGRAGLGRQPPGGCVLSLGLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGPQLLNPGTPVSPQERPPPYLAVPG-------HGEEYPAAGAHS--------------------------SPPKARFLRVPSEH---PYLTPSPESPEHWASPSPPSLSDWSESTPSPATATGAMATTTGALPAQPLPLSVPSSLAQAQTQLGPQPEVTPKRQVLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07207-1", "uniprot_id": "NOTCH_DROME", "id": "P07207-1", "name": "Neurogenic locus Notch protein", "aln": "-MQSQRSRRRSRAPNTWICFWINKMHAVASLPASLPLLLLTLAFANLPNTVRGTDTALVAASCTSVGCQNGGTCVTQLNG-KTYCACDSHYVGDYCEHRNPCNSMRCQNGGTCQVTFRNGRPGISCKCPLGFDESLCEIAVPNACDHVTCLNGGTCQLKTLEEYTCACANGYTGERCETKNLCASSPCRNGATCTALAGSSSFTCSCPPGFTGDTCSYDIEECQS-NPCKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKPCSPSPCQNGGICR-SNGLSYECKCPKGFEGKNCEQNYDDCLGHLCQNGGTCIDGISDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGATCTNTHGSYSCICVNGWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCTKGKTGLLCHLDDACTSNPCHADAICDTSPINGSYACSCATGYKGVDCSEDIDECDQGS-PCEHNGICVNTPGSYRCNCSQGFTGPRCETNINECESHPCQNEGSCLDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCLNDGTCHDKINGFKCSCALGFTGARCQINIDDCQSQPCRNRGICHDSIAGYSCECPPGYTGTSCEININDCDSNPCHRGKCIDDVNSFKCLCDPGYTGYICQKQINECESNPCQFDGHCQDRVGSYYCQCQAGTSGKNCEVNVNECHSNPCNNGATCIDGINSYKCQCVPGFTGQHCEKNVDECISSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDGINEFICHCPPGYTGKRC--ELDIDECSSNPCQHGGTCYDKLNAFSCQCMPGYTGQKCETNIDDCVTNPCGNGGTCIDKVNGYKCVCKVPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLNVPGSYRCLCTKGYEGRDCAINTDDCASFPCQNGGTCLDGIGDYSCLCVDGFDGKHCETDINECLSQPCQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESSCLNGGSCIDGINGYNCSCLAGYSGANCQYKLNKCDSNPCLNGATCHEQNNEYTCHCPSGFTGKQCSEYVDWCGQSPCENGATCSQMKHQFSCKCSAGWTGKLCDVQTISCQDAADRKGLSLRQLCN-NGTCKDYGNSHVCYCSQGYAGSYCQKEIDECQSQPCQNGGTCRDLIGAYECQCRQGFQGQNCELNIDDCAPNPCQNGGTCHDRVMNFSCSCPPGTMGIICEINKDDCKPG-------ACHNNGSCIDRVGGFECVCQPGFVGARCEGDINECLSNPCSNAGTLDCVQLVN-NYHCNCRPGHMGRHCEHKVDFCAQSPCQNGGNCN--IRQSG---HHCICNNGFYGKNCELSGQDCDSNPCRVGNCVVADEGFGYRCECPRGTLGEHCEID-------TLDECSPNPCAQGAACEDLLGD--YECLCPSKWKGKRCDIYDANYPGWNGGSGSGNDRYAADLEQQRAMCDKRGCTEKQGNGICDSDCNTYACNFDGNDCSLGIN-PWANCTANECWNKFKNGKCNEECNNAACHYDGHDCER--KLKSCDSLFDAYCQKHYGDGFCDYGCNNAECSWDGLDCENKTQSPVLAEGAMSVVMLMNVEAFREIQAQFLRNMSHMLRTTVRLKKDALGHDIIINWKDNVRVPEIEDTDFARKNKILYTQQVHQTGIQIYLEIDNRKCTECFTHAVEAAEFLAATAAKHQLRNDFQIHSVRGIKNPGDEDNGEPPANVKYVITGIILVIIALAFFGMVLSTQRKRAHGVTWFPEGFRAPAAVMS--RRRRDPHGQEMRNLNKQVAMQSQGVGQPGAHWSDDESDMPLPKRQRSDPVSGVGLGNNGGYASDHTMVSEYEEADQRVWSQAHLDVVDVR-----AIMTPPAHQDGGKHDVDARGPCGLTPLMIAAVRGGGLDTGEDIEN-NEDSTAQVISDLLAQGAELNATMDKTGETSLHLAARFARADAAKRLLDAGADANCQDNTGRTPLHAAVAADAMGVFQILLRNRATNLNARMHDGTTPLILAARLAIEGMVEDLITADADINAADNSGKTALHWAAAVNNTEAVNILLMHHANRDAQDDKDETPLFLAAREGSYEACKALLDNFANREITDHMDRLPRDVASERLHHDIVRLLDEHVPRSPQMLSMTPQAMIGSPPPGQQQPQLITQPTVISAGNGGNNGNGNASGKQSNQTAKQKAAKKAKLIEGSPDNGLDATGSLRRKASSKKTSAASKKAANLNGLNPGQLTGGVSGVPGVPPTNSAAQAAAAAAAAVAAMSHELEGSPVGVGMGGNLPSPYDTSSMYSNAMAAPLANGNPNTGAKQPPSYEDCIKNAQSMQSLQGNGLDMIKLDNYAYSMGSPFQQELLNGQGLGMNGNGQRNGVGPGVLPGGLCGMGGLSGAGNGNSHEQGLSPPYSNQSPPHSVQSSLALSPHAYLGSPSPAKSRPSLPTSPTHIQAMRHATQQKQFGGSNLNSLLGG--ANGGGVVGGGGGGGGGVG-QGPQNSPVSLGIISPTGSDMGIMLAPPQSSKNSAIMQTISPQQQQQQQQQQQQQHQQQQQQQQQQQQQQQQQLGGLEFGSAGLDLNGFCGSPDSFHSGQMNPPSIQSSMSGSSPSTNMLSPSSQHNQQAFYQYLTPSSQHSGGHTPQHLVQTLDSYPTPSPESPGHWSSSSPRSNSDWSEGVQSPAANNLYISGGHQANKGSEAIYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.*** * * .. *. .* * * :*. * .... . * *** *. * . :: * * . :**: *: .:**:* * . *.** :. * . :**:* *: * *. : * * ** :** *:. . .. : *:****: * .* *::**: .*::****:** **::* ** **** *:. **:****:*** ** *..::*:* * ****:*** * *** ** * *****:**:. *.*:***::**:** :***** : : .*:**.** * *.:**:*****:* .**:* *** *.**:**** * *.**** *. *************.***** ******.*:.* *:*..*:.* *.:*:***. *: **** * **** **: *:*.:*:*******::*** * **:*:.:*** * * *:**.***** **:*******.**:*.*.*:*::***.*:*. **:*: **:::*:* * **** . * *. **.*.*. *: ** *: *::**..:***:*:*:*.: **.* * ***** *:.*::**.*:**:..*:* * *..* *:* .**:* *****:::* ****. * .* **** *.* * ***** *: :::** ****.:.* *:* **::* ** * . **. . ** :** .* * *. . * * * **::* ** .* * *.*:**: **** .. .* * * ** *::** :.**:.. *:: .:* . .. * . *:* *: * *::*:***: .:** . * *:.*.: * * ** * * : :** . ** :**:* **:*.:** *: ** * :* *::****.** * **:::* *:**:** *:.*::*: : **: ***:***:*:**:..:.* * .**:*::**:: : * *.***:*. * : : * * ..*** **. ****.: **:**. * * * *.. *:* ***: ::.* :** : *: *.***: .* * * . ** * *.:* **:*::*:* * :****:*****. :*.* *:* *: *:.** ::*:**.:***:**:* * * .: *******:*::****:*** * * :**:*:* ****.* * **:.* :**.***** ...* * * **:* . ::* * .*. * :*: : * ..***:**:*. .* . * * *:* .** .:.* . * ** : * ** ** * * *. : .*:. ** :*.:* :.* *. * * **: * *.:: :: . * : .* *:*: ** :**: .*.:**.****.:. ** :* * :**. *:*.:*: *...** **..** : ::*:.::. ** .*:.** ** ***. **.****** .:. .:**.*.: :.:*: * : . .*:**:.:* :***::*:: ** *: ::: :: * . .:. *: .* *: * :.. : .**..* .**::*.* :* .:* : ::.*** * . . : :::* ::::: : : *: ::*** *.. ****** : : : **:* **: .::: . :* :*: :. * :: * .** : *. *:* : * * * *:* ** ..*:* *: .* .. *.. **:.*** *:****:*:. **.*:. *: :*::*.:****:.***:*.* *:****:******:***************:*.**::******:**:*** ******:***:*:*:*** **:*.********:*****:**::.**:**.*: **:**********.**. ** : **:* **.*:***************.* ***::********:********.****:*******: *.* :.* .* *: * ... * .. *. : ::: . .* .*:* * .*.*:: : .* .:**::*** *.** * . *: * ** *:. . *. .:. *. . :* * * .. :*:*::.*.. :. ** :. ..::: .::* * : . ::: * *: :** *...:.:* .*:* .: . *.:* .. :* * : :* *:*:. : :::.. . . . .* . .: * : . .. : ", "identical_positions": 983, "similar_positions": 678, "identity": "35.78%" }, { "cls_id": "homologset.agr.RGD:620762", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R455-1", "uniprot_id": "TRPM8_RAT", "id": "Q8R455-1", "name": "Transient receptor potential cation channel subfamily M member 8", "aln": "MSFEGARLSMRSRRNGTLGSTRTLYSSVSRSTDVSYSESDLVNFIQANFKKRECVFFTRDSKAMESICKCGYAQSQHIEGTQINQNEKWNYKKHTKEFPTDAFGDIQFETLGKKGKYLRLSCDTDSETLYELLTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRNSEENIVAIGIAAWGMVSNRDTLIRNCDDEGHFSAQYIMDDFMRDPLYILDNNHTHLLLVDNGCHGHPTVEAKLRNQLEKYISERTSQDSNYGGKIPIVCFAQGGGRETLKAINTSVKSKIPCVVVEGSGQIADVIASLVEVEDVLTSSMVKEKLVRFLPRTVSRLPEEEIESWIKWLKEILESPHLLTVIKMEEAGDEVVSSAISYALYKAFSTNEQDKDNWNGQLKLLLEWNQLDLASDEIFTNDRRWESADLQEVMFTALIKDRPKFVRLFLENGLNLQKFLTNEVLTELFSTHFSTLVYRNLQIAKNSYNDALLTFVWKLVANFRRSFWKEDRSSREDLDVELHDASLTTRHPLQALFIWAILQNKKELSKVIWEQTKGCTLAALGASKLLKTLAKVKNDINAAGESEELANEYETRAVELFTECYSSDEDLAEQLLVYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFIIPLVGCGLVSFRKKPIDKHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHTPELILYALVFVLFCDEVRQWYMNGVNYFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFRSVIYEPYLAMFGQVPSDVDSTTYDFSHCTFSGNESKPLCVELDEYNLPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGIVQENNDQVWKFQRYFLVQEYCNRLNIPFPFVVFAYFYMVVKKCFKCCCKEKNTESSACCFRNEDNETLAWEGVMKENYLVKINTKANDNAEEMRHRFRQLDTKLNDLKGLLKEIANKIK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4D5-1", "uniprot_id": "TRPM8_MOUSE", "id": "Q8R4D5-1", "name": "Transient receptor potential cation channel subfamily M member 8", "aln": "MSFEGARLSMRSRRNGTMGSTRTLYSSVSRSTDVSYSDSDLVNFIQANFKKRECVFFTRDSKAMENICKCGYAQSQHIEGTQINQNEKWNYKKHTKEFPTDAFGDIQFETLGKKGKYLRLSCDTDSETLYELLTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRNSEENIVAIGIAAWGMVSNRDTLIRSCDDEGHFSAQYIMDDFTRDPLYILDNNHTHLLLVDNGCHGHPTVEAKLRNQLEKYISERTSQDSNYGGKIPIVCFAQGGGRETLKAINTSVKSKIPCVVVEGSGQIADVIASLVEVEDVLTSSMVKEKLVRFLPRTVSRLPEEEIESWIKWLKEILESSHLLTVIKMEEAGDEIVSNAISYALYKAFSTNEQDKDNWNGQLKLLLEWNQLDLASDEIFTNDRRWESADLQEVMFTALIKDRPKFVRLFLENGLNLQKFLTNEVLTELFSTHFSTLVYRNLQIAKNSYNDALLTFVWKLVANFRRSFWKEDRSSREDLDVELHDASLTTRHPLQALFIWAILQNKKELSKVIWEQTKGCTLAALGASKLLKTLAKVKNDINAAGESEELANEYETRAVELFTECYSNDEDLAEQLLVYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFIIPLVGCGLVSFRKKPIDKHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHTPELILYALVFVLFCDEVRQWYMNGVNYFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFRSVIYEPYLAMFGQVPSDVDSTTYDFSHCTFSGNESKPLCVELDEHNLPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGIVQENNDQVWKFQRYFLVQEYCNRLNIPFPFVVFAYFYMVVKKCFKCCCKEKNMESNACCFRNEDNETLAWEGVMKENYLVKINTKANDNSEEMRHRFRQLDSKLNDLKSLLKEIANNIK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z2W7-1", "uniprot_id": "TRPM8_HUMAN", "id": "Q7Z2W7-1", "name": "Transient receptor potential cation channel subfamily M member 8", "aln": "MSFRAARLSMRNRRNDTLDSTRTLYSSASRSTDLSYSESDLVNFIQANFKKRECVFFTKDSKATENVCKCGYAQSQHMEGTQINQSEKWNYKKHTKEFPTDAFGDIQFETLGKKGKYIRLSCDTDAEILYELLTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRSSEENIVAIGIAAWGMVSNRDTLIRNCDAEGYFLAQYLMDDFTRDPLYILDNNHTHLLLVDNGCHGHPTVEAKLRNQLEKYISERTIQDSNYGGKIPIVCFAQGGGKETLKAINTSIKNKIPCVVVEGSGQIADVIASLVEVEDALTSSAVKEKLVRFLPRTVSRLPEEETESWIKWLKEILECSHLLTVIKMEEAGDEIVSNAISYALYKAFSTSEQDKDNWNGQLKLLLEWNQLDLANDEIFTNDRRWESADLQEVMFTALIKDRPKFVRLFLENGLNLRKFLTHDVLTELFSNHFSTLVYRNLQIAKNSYNDALLTFVWKLVANFRRGFRKEDRNGRDEMDIELHDVSPITRHPLQALFIWAILQNKKELSKVIWEQTRGCTLAALGASKLLKTLAKVKNDINAAGESEELANEYETRAVELFTECYSSDEDLAEQLLVYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFIIPLVGCGFVSFRKKPVDKHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHPPELVLYSLVFVLFCDEVRQWYVNGVNYFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFRSVIYEPYLAMFGQVPSDVDGTTYDFAHCTFTGNESKPLCVELDEHNLPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGTVQENNDQVWKFQRYFLVQEYCSRLNIPFPFIVFAYFYMVVKKCFKCCCKEKNMESSVCCFKNEDNETLAWEGVMKENYLVKINTKANDTSEEMRHRFRQLDTKLNDLKGLLKEIANKIK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***..******.***.*:.********.*****:***:********************:**** *.:**********:*******.*******************************:*******:* ***************************************************************************.************************.** **:* ***:**** ******************************************* *******************:*********:*.*************************.**** ******************** ************..**************:**.************.***********************.*****************************************:****::*******.**********************************.* ****..*:::*:****.* ****************************:*************************************************.*************************************************************************:*******:************************************************.***:**:**************:************************************************************************************************************************************.*****:****:*************:************************************** *********************.********:********************* **..***:***************************.:***********:******.*******:**", "identical_positions": 1027, "similar_positions": 64, "identity": "93.03%" }, { "cls_id": "homologset.agr.RGD:620763", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES72-1", "uniprot_id": "CCN1_RAT", "id": "Q9ES72-1", "name": "CCN family member 1", "aln": "---------MSSSTIKTLAVAVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDG----------CGCCKVCAK------------------QLNEDCSKTQPCDHTKG-------------------LECNFGASS--TALKGICRAQSEGRPCEYN--------------------SRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVSG-QCCEEWVCD--EDSIKDSLDDQDDLLG----FDASEVELTRNNELIAIGKGSSLKRLPVFGTEPRVLYNPLHAHGQKCIVQTTSWSQCSKSCGTGISTRVTNDNSECRLVKETRICEVRPCGQPVYS-SLKKGKKCSKTKKSPEPVRFTYAGCSSVKKYRPKYCGSCVDGRCCTPLQTRTVKMRFRCEDGEMFSKNVMMIQSCKCN----YNCPHPNEASFRLYSLFNDIHKFRD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18406-1", "uniprot_id": "CCN1_MOUSE", "id": "P18406-1", "name": "CCN family member 1", "aln": "---------MSSSTFRTLAVAVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDG----------CGCCKVCAK------------------QLNEDCSKTQPCDHTKG-------------------LECNFGASS--TALKGICRAQSEGRPCEYN--------------------SRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVSG-QCCEEWVCD--EDSIKDSLDDQDDLLG----LDASEVELTRNNELIAIGKGSSLKRLPVFGTEPRVLFNPLHAHGQKCIVQTTSWSQCSKSCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYS-SLKKGKKCSKTKKSPEPVRFTYAGCSSVKKYRPKYCGSCVDGRCCTPLQTRTVKMRFRCEDGEMFSKNVMMIQSCKCN----YNCPHPNEASFRLYSLFNDIHKFRD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00622-1", "uniprot_id": "CCN1_HUMAN", "id": "O00622-1", "name": "CCN family member 1", "aln": "---------MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDG----------CGCCKVCAK------------------QLNEDCSKTQPCDHTKG-------------------LECNFGASS--TALKGICRAQSEGRPCEYN--------------------SRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTG-QCCEEWVCD--EDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQ--GQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYS-SLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCN----YNCPHANEAAFPFYRLFNDIHKFRD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVK3-1", "uniprot_id": "Q9VVK3_DROME", "id": "Q9VVK3-1", "name": "", "aln": "MLILLPLLGIFGNGFVAEVEANLSLGFKAIKLPRHPNPANCSVGNTTFAHGVTFKLDCKTQCVCENGRHACSTLCPNEQLPAPEDTISCRSPRLVEVPGHCCKMWLCENPTADVYATCHNSTTSGNWTACSRSCGLGTATRHTTTHAGCHQLSNLRLCENRRCDKDDHEDNKWSRSRPLTHKRKQHRAHSHSHQRYHHHKEHEEPAHRIRKGHECRSIQRLGPARIRLGECVSRKLYRPKLCGRCHRGVKCCAPAVSTTIQVELLCPLNAVDPINYVQRRQANKKRQMKEPQDDEDDDDDDDGDDNVEPEPVLQSAQLWDTVALEPIDQEFLQSHQIQIENKFIAVEWILKCECSTKNCNAGSSNISSNSNSNDNMANTNKYGYYNYKNNNRGRNHETNGEPNEPTNNNAGNNKDNEEDVVDSGNNLDHNDVDNMSSEQQPDIIPYPPSVGESSWKAEKLRQQHHWQQNT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . * :. : *. * ..:*.: .. * ** : * .*..:*.: :: .*.* *::... .*.:*::: *: :. *: *: * ** . .* :...*.. : *: . : .. * : *: .** .. ** : . : . :*. . .:* . : . *: . : .* .:*. : . : : : .: *. : : : : * ::: * : . . : : * : ..:.....: .:. :: * . . :: * : .. : . ... : . :.*: :.:* : *.: : * .*::: * :: * :: ", "identical_positions": 48, "similar_positions": 148, "identity": "10.21%" }, { "cls_id": "homologset.agr.RGD:620764", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925S8-1", "uniprot_id": "YMEL1_RAT", "id": "Q925S8-1", "name": "ATP-dependent zinc metalloprotease YME1L1", "aln": "MFSLSSTVQPQVTV-------PLSHLIN--AFHSPKNISVSVN-TSASPKQHRDTVAEHEAPSSE---------------------------------------------------------PVLNLRDLGLS-ELKIGQIDKLVENLLPGFYKDKRVSSCWHTSHISAQSFFENKYGHLDMFSTLRSSSLYRQHPKTLQSICSDLQNFPVFIQS-----RGFKT---LKSRTRRLQSTSERLAEAQNIAPSFVKGFLLRDRGTDLESLDKLMK-TKNIPEAHQDAFKTGFAEGFLKAQ-----ALTQKTNDSLRRTRLILFVLLLFGIYG-LLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTVLGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIEFPMHPYSRQTIIQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDKSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNEIRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTG------KLSPETQSAIEQEIRILLRESYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88967-1", "uniprot_id": "YMEL1_MOUSE", "id": "O88967-1", "name": "ATP-dependent zinc metalloprotease YME1L1", "aln": "MFSLSSTVQPQVTI-------PLSHLIN--AFHSPKNISVSVN-TPVSQKQHRDTVPEHEAPSSE---------------------------------------------------------PVLNLRDLGLS-ELKIGQIDKMVENLLPGFYKDKRVSSCWHTSHISAQSFFENKYGHLDMFSTLRSSSLYRQHPKTLRSICSDLQYFPVFIQS-----RGFKT---LKSRTRRLQSTSERLVEAQNIAPSFVKGFLLRDRGTDLESLDKLMK-TKNIPEAHQDAFKTGFAEGFLKAQ-----ALTQKTNDSLRRTRLILFVLLLFGIYG-LLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTVLGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDKSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTG------KLSPETQSAIEQEIRILLRESYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96TA2-1", "uniprot_id": "YMEL1_HUMAN", "id": "Q96TA2-1", "name": "ATP-dependent zinc metalloprotease YME1L1", "aln": "MFSLSSTVQPQVTV-------PLSHLIN--AFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSECMFSDFLTKLNIVSIGKGKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPEPFSLSIPPSLNLRDLGLS-ELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSCLYRHHSRALQSICSDLQYWPVFIQS-----RGFKT---LKSRTRRLQSTSERLAETQNIAPSFVKGFLLRDRGSDVESLDKLMK-TKNIPEAHQDAFKTGFAEGFLKAQ-----ALTQKTNDSLRRTRLILFVLLLFGIYG-LLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTG------KLSPETQSAIEQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F3YDF1-1", "uniprot_id": "YMEL1_DROME", "id": "F3YDF1-1", "name": "ATP-dependent zinc metalloprotease YME1L", "aln": "MFSTTTHSVPYLYLGNF-SRKPHYYSVNRTKLHGSAGAARLSKSTSTSSRSHDLVLDLRNLLSRSS-----------------------------------------------------ASIQGMVERAARLNGILDRRLVDDVLAKVTSMLPSMRDVRVTLEESATQIGRVQLQNYQFEVSLTGAAGSVPTGANVKVIPTITPGLLR-PLFSQQQLNQIRGFKTDRSIEAEQKRNPTMTSRLKNALANSPQRLDG----DTPLQAEKLRRLLAKSEEHGFNKAESLKIAFAEGYLAAANSEDSPKSGKTMKYLKTLQTIVVIVVFLGIFLSFFTTSNGSVFRSIQLGNQVEVDPEEIN-VTFEDVKGCDEAKQELKEVVEFLKSPEKFSNLGGKLPKGVLLVGPPGTGKTLLARAVAGEAKVPFFHAAGPEFDEVLVGQGARRVRDLFKAAKARAPCVIFIDEIDSVGAKRTNSVLHPYANQTINQLLSEMDGFHQNAGVIVLGATNRRDDLDQALLRPGRFDVEVMVSTPDFTGRKEILSLYLTKILHDE-IDLDMLARGTSGFTGADLENMINQAALRAAIDGAETVSMKHLETARDKVLMGPERKARLPDEEANTITAYHEGGHAIVAFYTKESHPLHKVTIMPRGPSLGHTAYIPEKERYHVTKAQLLAMMDTMMGGRAAEELVFGTDKITSGASSDLKQATSIATHMVRDWGMSDKVGLRTIEASKGLGTGDTLGPNTIEAVDAEIKRILSDSYERAKAILRKHTREHKALAEALLKYETLDADDIKAILNESQT-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32795-1", "uniprot_id": "YME1_YEAST", "id": "P32795-1", "name": "Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1", "aln": "MNVSKILVSPTVTTNVLRIFAPRLPQIGASLLVQKKWALRSKKFYRFYSEKNSGEMPPKKEADSSG--------------------------------------------------------KASNKSTISSIDNSQPPPPSNTNDKTKQANVAVSHAMLATREQEANKDLTSPDAQAAFYKLLLQSNYPQYVVSRFETPGIASSPECMELYMEA-------------LQRIGRHSEADAVRQNLLTASSAGAVNPSLASSSSNQSGYHGNFPSMYSPLYGSRKEPLHVVVSESTFTVVS-------------RWVKWLLVFGILTYSFSEGFKYITENTTLLKSSEVADKSVDVAKTN-VKFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFIDELDAIGGKRNPK-DQAYAKQTLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDKVVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSVDMSHFEWAKDKILMGAERKTMVLTDAARKATAFHEAGHAIMAKYTNGATPLYKATILPRGRALGITFQLPEMDKVDITKRECQARLDVCMGGKIAEELIYGKDNTTSGCGSDLQSATGTARAMVTQYGMSDDVGPVNLSENWES-----WSNKIRDIADNEVIELLKDSEERARRLLTKKNVELHRLAQGLIEYETLDAHEIEQVCKGEKLDKLKTSTNTVVEGPDSDERKDIGDDKPKIPTMLNA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * : * :. : . ..: : :: . . . .. : . . . : : . * .. :: : :: :: : : * :. :. . : .: . : :.:: .:*. : . ::. :: .: : . :. : ** : : *.*:.* * :**: **:*:*:***.* *: ********:**.*************.**** * *:. :*.****: ** ** *:*:** *::.**.:*****:*::*.** :.*:.**: *** *:*** . *:*::**** : **:** ****** * * **. ** :**. ::.** . :* ::**** *::**:* *::****: *. .. * *..:* ::**:***.**:: : .. **:**.****:* **: : *: *.**:*** :** . :** :: . : : * :*. ***: ****::*.*: *:*..**:..** * ** .:***:.:* . . . . : . : *: :* :* ***: :* .: * : **:.*: ******.:*: : : .: ", "identical_positions": 202, "similar_positions": 199, "identity": "24.16%" }, { "cls_id": "homologset.agr.RGD:620765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91WW1-1", "uniprot_id": "UCN2_RAT", "id": "Q91WW1-1", "name": "Urocortin-2", "aln": "-MTRWALVVFMVLMLDR---VPGTPIPTFQLLPQNYPETTPSSVSSESPSDTTTGPSASWSNSKASPYLDTRVILSLDVPIGLLRILLEQARNKAARNQAATNAQILARVGRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99ML8-1", "uniprot_id": "UCN2_MOUSE", "id": "Q99ML8-1", "name": "Urocortin-2", "aln": "MMTRWALVVFVVLMLDRILFVPGTPIPTFQLLPQNSLETTPSSVTSESSSGTTTGPSASWSNSKASPYLDTRVILSLDVPIGLLRILLEQARYKAARNQAATNAQILAHVGRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RP3-1", "uniprot_id": "UCN2_HUMAN", "id": "Q96RP3-1", "name": "Urocortin-2", "aln": "-MTRCALLLLMVLMLGRVLVVPVTPIPTFQLRPQNSPQTTPRPAASESPSAAPTWPWAAQSHCSPTRHPGSRIVLSLDVPIGLLQILLEQARARAAREQATTNARILARVGHC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** **::::****.* ** ******** *** :*** ..:***.* :.* * *: *:...: : .:*::**********:******* :***:**:***:***:**: ", "identical_positions": 65, "similar_positions": 30, "identity": "57.52%" }, { "cls_id": "homologset.agr.RGD:620766", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VR15-1", "uniprot_id": "Q9VR15_DROME", "id": "Q9VR15-1", "name": "Peptidase S1 domain-containing protein", "aln": "-----------------------------------------------------------------------------MRVYLALPLLLLGIG----LSLAQY----------------------------------QYQAP--------------------------------------------HQTLAQQFADVVDVVDPAEQSIKAVRPPKSRNQCTAKQN----------------CFCGTPN-----VNRIVGGQQVRSNKYPWTAQLVKGRHYPRLFCGGSLINDRYVLTAAHCVHGNRDQ-ITIRLLQIDRSSR--DPGIVRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLT-GNMRPVCLP-EANHN--FDGKTAVVAGWGLIKEGGVTSNYLQEVNVPVITNAQCRQ-TRYK-DKIAEVMLCAGLVQQGGKDACQGDSGGPLIVN---EG-RYKLAGVVSFGYGCAQKNAPGVYARVSKFLDWIRKNTADGCYCQS-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUF0-1", "uniprot_id": "Q9VUF0_DROME", "id": "Q9VUF0-1", "name": "Peptidase S1 domain-containing protein", "aln": "-----------------------------------------------------------------------------MKLNPPAFLLLLALISICDRSWAVY----------------------------------NYKPPSRGYFYPKPERLPPLPVNGSTTSSTGPPPGVQSDFIDDLIEGHKQQILSNVLGVASETPSDTASSLGSTSLSSSASPVFPLEGGG---AKAFRVNRCASCTCGVPN-----VNRIVGGTQVRTNKYPWIAQIIRG---TFLFCGGTLINDRYVLTAAHCVHGMDMRGVSVRLLQLDRSST--HLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLV-DTMRPACLPSNWLQN--FDFQKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQCRA-TSYR-SMIVDTMMCAGYVKTGGRDACQGDSGGPLIVR---DR-IFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWIAVNTRDSCYCIN-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2C8-1", "uniprot_id": "Q9W2C8_DROME", "id": "Q9W2C8-1", "name": "", "aln": "-----------------------------------------------------------------------------MNRAWLCLLICLALSCGPSQSASQ-----------------------------------DRATN-QTAASPLLKQSQNTFIQWVLSLLPQRPGSSDSENATLATLSSSSMMPDAASTTSTTTPAPSSSTTTTRRATTPAPPTL------------NPPRNCSDCVCGIANI----QKRIVGGQETEVHQYPWVAMLLYGG---RFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDRKMS-HMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFN-EVLHPVCMPTPGRS---FKGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRK-SRYG-NKITDNMLCGGYDE-GGKDSCQGDSGGPLHIVASGTR-EHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKNLTKQACLCQQ-----------------------------------ETKKIK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7V4-1", "uniprot_id": "Q9I7V4_DROME", "id": "Q9I7V4-1", "name": "Peptidase S1 domain-containing protein", "aln": "-----------------------------------------------------------------------------MCNFHLLLILATALGDLACATPSL-----------------------------------RSASDPEKILNNLAQLRQSSFLDWIQSILG------------------------------PEVPAEWSS---------PAK------------------RECAECSCGNINT----RHRIVGGQETEVHEYPWMIMLMWFG---NFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDS-HVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLG-IDMHPVCMPTPSEN---YAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRN-SNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGD--AYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTRDACSCAQPEAAGEPASPMETTEQGDQENTTANGAAEADPEVEEANKLI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KVM3-1", "uniprot_id": "Q7KVM3_DROME", "id": "Q7KVM3-1", "name": "Peptidase S1 domain-containing protein", "aln": "-----------------------------------------------------------------------------MKLPWILIALFCGLCSGSTERRIRP----------------------------------NEGKIFEWLGSILLPSTTTTTSTPVVATTS----------------------------TTTRRTTTTSSTTSRTTTSRTTVANF------------PIERDCVTCRCGLINT----LYKIVGGQETRVHQYPWMAVILIYN---RFYCSGSLINDLYVLTAAHCVEGVPPELITLRFLEHNRSHSNDDIVIQRYVSRVKVHELYNPRSFDNDLAVLRLNQPLDMRHHRLRPICLPVQSYS---FDHELGIVAGWGAQREGGFGTDTLREVDVVVLPQSECRNGTTYRPGQITDNMMCAGYISEGGKDACSGDSGGPLQTTFDEQPGQYQLAGIVSWGVGCARPQSPGVYTRVNQYLRWLGSNTPGGCHCMP---------------------------------YPEEDY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUG2-1", "uniprot_id": "Q9VUG2_DROME", "id": "Q9VUG2-1", "name": "Peptidase S1 domain-containing protein", "aln": "--------------------------------------------------------------------------MMMLHLRHWPLVLAMASCLLFTAATSAT----------------------------------PATPATPATSAPPATSTATSSLSSIPGKYQALG----------------AAHHQAKKLKIGDVNASSSDANKPVFRQNPIKNWFGAFNRNNSPAAQNQTSPTCSCRCGERND----ESRIVGGTTTGVSEYPWMARLSYFN---RFYCGGTLINDRYVLTAAHCVKGFMWFMIKVTFGEHDRCND-KERPETRFVLRAFS-QKFSFSNFDNDIALLRLNDRVPIT-SFIRPICLPRVEQRQDLFVGTKAIATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDK-RFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWIVENSRDGCFCDEDY---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A4D6K1E7-1", "uniprot_id": "A0A4D6K1E7_DROME", "id": "A0A4D6K1E7-1", "name": "Peptidase S1 domain-containing protein", "aln": "-----------------------------------------------------------------------------MSLKYIIFFWMLTANYSSVLSLEYS----------------------------------KGFNESDAINTIHTGHNKRTSKFLFDTIFR----------------------------ISSGVSNAFGLSDTEDEVEYTENSSLKN----------------CDCDCGFSNE----EIRIVGGKPTGVNQYPWMARIVYDG---KFHCGGSLLTKDYVLSAAHCVKKLRKSKIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFS-KIIKPICLPRYNYDP---AGRIGTVVGWGRTSEGGELPSIVNQVKVPIMSITECRN-QRYKSTRITSSMLCAGRPS---MDSCQGDSGGPLLLS---NGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSNLENTCLCS------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6P7D7-1", "uniprot_id": "Q6P7D7_RAT", "id": "Q6P7D7-1", "name": "Transmembrane protease serine 2", "aln": "MALNSGSPPGIGPYYENHGYQSEHVYSPRPPVSPSGYNLYPAQSCPSPVPQYAPRVTTQASTPAIHIQPRS-SGTLCTSKSKKSMLVALALGTVLAGAAVAAGLLWKFWDSKCSSSEMECGSSGTCISSSLWCDGVSQCPNGEDENRCVRLYGTSFTLQVYSSQRKAWYPVCQDDWNESYGRAACKDMGYKNSFYSSQGIPDQSGATSFMKLNVSAGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRS-VRRQSRIVGGSTASPGDWPWQVSLHVQG---IHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILKQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFN-DVVKPVCLPNPGMMLD--LAQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYN-NLITPAMICAGFLQ-GSVDSCQGDSGGPLVTL---KNEIWWLIGDTSWGSGCAKAYRPGVYGNVTVFTDWIYQQMRANS---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIQ8-1", "uniprot_id": "TMPS2_MOUSE", "id": "Q9JIQ8-1", "name": "Transmembrane protease serine 2", "aln": "MALNSGSPPGIGPCYENHGYQSEHICPPRPPVAPNGYNLYPAQYYPSPVPQYAPRITTQASTSVIHTHPKS-SGALCTSKSKKSLCLALALGTVLTGAAVAAVLLWRFWDSNCSTSEMECGSSGTCISSSLWCDGVAHCPNGEDENRCVRLYGQSFILQVYSSQRKAWYPVCQDDWSESYGRAACKDMGYKNNFYSSQGIPDQSGATSFMKLNVSSGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRS-VKRQSRIVGGLNASPGDWPWQVSLHVQG---VHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILRQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFN-DLVKPVCLPNPGMMLD--LDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYN-NLITPAMICAGFLQ-GSVDSCQGDSGGPLVTL---KNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWIYQQMRANS---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15393-1", "uniprot_id": "TMPS2_HUMAN", "id": "O15393-1", "name": "Transmembrane protease serine 2", "aln": "MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQN---VHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFN-DLVKPVCLPNPGMMLQ--PEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYD-NLITPAMICAGFLQ-GNVDSCQGDSGGPLVTS---KNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG---------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . :**** . :** : *..:::. : ::*:*** * . :. *:*:::: : : ::* *:* *** * . :. . * :: .* * *. *:*.* *:*.******: * .*:* **.: **** .* : *: ", "identical_positions": 48, "similar_positions": 49, "identity": "8.76%" }, { "cls_id": "homologset.agr.RGD:620767", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K2B0-1", "uniprot_id": "SC65_MOUSE", "id": "Q8K2B0-1", "name": "Endoplasmic reticulum protein SC65", "aln": "MARGAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLATAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPATSQPRPASGPDGDHDGDGEDWARELRLFGHVLERAACLRRCKKTLPAFQVPYPPRQLLRDFQSRLPYQYLHYAHFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYRGMLDIGDESLTDLEAQPYEAVFLRAVKLYNSGDFRSSTEDMERALAEYMTVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCETNLTPNVGGFFVDKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEDEDFQPREEAMLYHNQTSELRELLDFTHMYLQSDDEMELEETESLPEPEEPLSDAEFEGEGDYEEGLYADWWQEPEAKGDEAEAEPEPELT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64375-1", "uniprot_id": "SC65_RAT", "id": "Q64375-1", "name": "Endoplasmic reticulum protein SC65", "aln": "MARAAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLATAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPATSQPRPAPGPDGDNEGDGEDWARELRLFGHVLERAACLRRCKRTLPAFQVPYPSRQLLRDFQNRLPYQYLHYAHFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYRGMLDIGDESLTDLEAQPYEAVFLQAVKLYNSGDFRSSTEHMERALADYMTVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCEANLTPNVGGFFVDKFVATMYHYLQFAYYKLNDVHQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEEEDFQPREEAVLYHNQTSELRELLDFTHMYLQSDDEMELEETESLPEPEKPLSDAEFEGEGDYEEGLYADWWQEPDAKGDEDEAEPEPELA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92791-1", "uniprot_id": "SC65_HUMAN", "id": "Q92791-1", "name": "Endoplasmic reticulum protein SC65", "aln": "MARVAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLAAAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPAPAAK---PDPDG---GRADEWACELRLFGRVLERAACLRRCKRTLPAFQVPYPPRQLLRDFQSRLPYQYLHYALFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYQGMLDVADESLTDLEAQPYEAVFLRAVKLYNSGDFRSSTEDMERALSEYLAVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCEANLTPNVGGYFVDKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEEEDFQPREEAMLYHNQTAELRELLEFTHMYLQSDDEMELEETEPPLEPEDALSDAEFEGEGDYEEGMYADWWQEPDAKGDEAEAEPEPELA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *********************************:**********************************************.: ..*** * .::** ******:************:**********.********.********** *********************************:****:.*****************:***************.*****::*::****************************************:********:***********************:************************************:*********:******:******:******************. ***..***************:********:***** ********:", "identical_positions": 394, "similar_positions": 34, "identity": "88.94%" }, { "cls_id": "homologset.agr.RGD:620768", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88917-1", "uniprot_id": "AGRL1_RAT", "id": "O88917-1", "name": "Adhesion G protein-coupled receptor L1", "aln": "MARLAAALWSLCVTTVLVTSATQGLSRAGLPFGLMRRELACEGYPIELRCPGSDVIMVENANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQCVVVAGSDAFPDPCPGTYKYLEVQYDCVPYKVEQKVFVCPGTLQKVLEPTSTHESEHQSGAWCKDPLQAGDRIYVMPWIPYRTDTLTEYASWEDYVAARHTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGETVINTANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTLRFEGTWETGYDKRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNTNANREEPVSLAFPNPYQFVSSVDYNPRDNQLYVWNNYFVVRYSLEFGPPDPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPAPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCLPALGLWNPRGPDLSNCTSPWVNQVAQKIKSGEN-AANIASELARHTRG-SIYAGDVSSSVKLMEQLLDILDAQLQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKQNVVLEVTVLSTEGQVQELVFPQ---EYASESSIQLSANTIKQNSRNGVVKVVFILYNNLGLFLS---------------TENATVKLAGEAGTGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEAKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHRE---IYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRG--LQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEVACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLV----EVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWS-FIGPVSFVIVVNLVFLMVTLHKMIRSS--SVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFIN------KESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEY----------SKCLRHSYCCIRS----PPGGAHGSLKTSAMRSNTRYYTGTQVPGQGRHIHQVSLGPRGRSALPESQKDPGGQSGPGDPLTFGLCPSRIRRMWNDTVRKQTESSFMAGDINSTPTLN-----------------------------------------------------------------------------------------------------------RGTMGNHLLTNPVLQPRGGTSPYNTLIAESVGFNPSSPPVFNSPGSYREP--------------------------------------------KHPLG-GREACGMDTLPLN-------------GNFNNSYSLR----------SGDFPPGDGGPEPP-----RG-----------------RNLADAAAFEKMIISELVHNNLRGASGGAKGPPP----------------EPPVPPVPG-VSEDEAGGPGGADR--AEIELLYKALEEP--------------LLLPRAQSVLYQSDLDESESCTA------------EDGATSRPLSSPP---GRDSLYASGANLRDSPSYPDSSPEGPNEALPPPPPAPPGPPEIYYT--SRPPALVAR-NPLQGYYQVRRPSHEGYLAAPSLEGPGPDGDGQMQLVTSL--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TR1-1", "uniprot_id": "AGRL1_MOUSE", "id": "Q80TR1-1", "name": "Adhesion G protein-coupled receptor L1", "aln": "MARLAAALWSLCVTTVLVTSATQGLSRAGLPFGLMRRELACEGYPIELRCPGSDVIMVENANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQCVVVAGSDAFPDPCPGTYKYLEVQYDCVPY-----IFVCPGTLQKVLEPTSTHESEHQSGAWCKDPLQAGDRIYVMPWIPYRTDTLTEYASWEDYVAARHTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGETVINTANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTLRFEGTWETGYDKRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNTNANREEPVSLAFPNPYQFVSSVDYNPRDNQLYVWNNYFVVRYSLEFGPPDPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPAPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCLPALGLWNPRGPDLSNCTSPWVNQVAQKIKSGEN-AANIASELARHTRG-SIYAGDVSSSVKLMEQLLDILDAQLQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKQNVVLEVTVLNTEGQVQELVFPQ---EYPSENSIQLSANTIKQNSRNGVVKVVFILYNNLGLFLS---------------TENATVKLAGEAGTGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEAKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHRE---IYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRG--LQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEVACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLV----EVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWS-FIGPVSFVIVVNLVFLMVTLHKMIRSS--SVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFIN------KESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEY----------SKCLRHSYCCIRS----PPGGTHGSLKTSAMRSNTRYYTGTQS--------------------------------------------RIRRMWNDTVRKQTESSFMAGDINSTPTLN-----------------------------------------------------------------------------------------------------------RGTMGNHLLTNPVLQPRGGTSPYNTLIAESVGFNPSSPPVFNSPGSYREP--------------------------------------------KHPLG-GREACGMDTLPLN-------------GNFNNSYSLR----------SGDFPPGDGGPEPP-----RG-----------------RNLADAAAFEKMIISELVHNNLRGASGGAKGPPP----------------EPPVPPVPG-VSEDEAGGPGSADR--AEIELLYKALEEP--------------LLLPRAQSVLYQSDLDESESCTA------------EDGATSRPLSSPP---GRDSLYASGANLRDSPSYPDSSPEGPNEALPPPPPAPPGPPEIYYT--SRPPALVAR-NPLQGYYQVRRPSHEGYLAAPSLEGPGPDGDGQMQLVTSL--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94910-1", "uniprot_id": "AGRL1_HUMAN", "id": "O94910-1", "name": "Adhesion G protein-coupled receptor L1", "aln": "MARLAAVLWNLCVTAVLVTSATQGLSRAGLPFGLMRRELACEGYPIELRCPGSDVIMVENANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQCVVVAGSDAFPDPCPGTYKYLEVQYDCVPYKVEQKVFVCPGTLQKVLEPTSTHESEHQSGAWCKDPLQAGDRIYVMPWIPYRTDTLTEYASWEDYVAARHTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGETVINTANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTLRFEGTWETGYDKRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNTNANREEPVSLTFPNPYQFISSVDYNPRDNQLYVWNNYFVVRYSLEFGPPDPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPVPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCLPALGLWNPRGPDLSNCTSPWVNQVAQKIKSGEN-AANIASELARHTRG-SIYAGDVSSSVKLMEQLLDILDAQLQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQE--EYPRKNSIQLSAKTIKQNSRNGVVKVVFILYNNLGLFLS---------------TENATVKLAGEAGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHRE---IYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRG--LQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLV----EVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWS-FIGPVSFVIVVNLVFLMVTLHKMIRSS--SVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFIN------KESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEY----------SKCLRHSYCCIRS----PPGGTHGSLKTSAMRSNTRYYTGTQS--------------------------------------------RIRRMWNDTVRKQTESSFMAGDINSTPTLN-----------------------------------------------------------------------------------------------------------RGTMGNHLLTNPVLQPRGGTSPYNTLIAESVGFNPSSPPVFNSPGSYREP--------------------------------------------KHPLG-GREACGMDTLPLN-------------GNFNNSYSLR----------SGDFPPGDGGPEPP-----RG-----------------RNLADAAAFEKMIISELVHNNLRGSSSAAKGPPPP---------------EPPVPPVPGGGGEEEAGGPGGADR--AEIELLYKALEEP--------------LLLPRAQSVLYQSDLDESESCTA------------EDGATSRPLSSPP---GRDSLYASGANLRDSPSYPDSSPEGPSEALPPPPPAPPGPPEIYYT--SRPPALVAR-NPLQGYYQVRRPSHEGYLAAPGLEGPGPDGDGQMQLVTSL--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J3J7-1", "uniprot_id": "A0AC58J3J7_DANRE", "id": "A0AC58J3J7-1", "name": "", "aln": "MALALWILFTCTIALSHVRPSAQALSRSAMPFGLMRRELACEGYPIELRCPGSDVIMIETANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQCVVVAGSDVFPDPCPGTYKYLEIQYECVPYKVDQKVFVCPGTLLRVQAASLLQEAEHQSGAWCKDPLQSGDRLYVMPWTPYRTDMLYEYASWEDFKQNRATTTYKLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGEAIVNNANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEANNGRLVVSQVNPYTLRFEGTWETSFDKRLASNAFMACGVLYAVRSVYQDDDSEAGGDLVLYAYNTNRAREEPVHIPFPNPYQYVSSVDYNPRDNQLYVWNNYNVLRYPLEFGPPDPTAGPPVTTQMSSSTTTAARPITSTSLPSTIRPL---PPTAHPIGAINKA-PDLRPITATVPVTRRPLRVPPQGPEIEVCESRVARGVQWPATQKGETVDRPCPKGSLGIASFQCLSSPVLWNPRGPDLSNCTSPWVNQVAQKIKSGEN-AANIAAELVNHTQG-RIHAGDVSSSVRLIEQLLDILDAQLQALRPGNKESAARNYNKWQKRERTCRAYVQAVVQTVDNLLRAEALESWQDMNSTEQAHTATMLLDVMEKGAFLLANNMYN-NHFSDHAANVDLEVRVLNTETDSQDLSFPQ---SGPSDSSIQLSASTFKQYSRNGQVKVVFVLYKNLGSFLS---------------TENATVKMEMEAGIGGRG---LAVNSHVIAASINKESSRVFLTEPVVFTLRHLQLENHFSPNCSFWNYSERSMTGQWSSQGCRLIETNSTHTTCSCSHLTNFAVLMVHHEP--DYPGRMHELILFVITWVGIVISLVCLAICISTFCFLRG--LQTDRNTIHKNLCINLFIAELLFLIGIDKTQYHIACPIFAGLLHFFFLAAFSWMCLEGIQLYLMLV----EVFESEYSRKKYYYLCGYCFPALVVGISAAIDYRSYGTKKACWLRVDNYFIWS-FIGPVSFIIMLNLVFLMITLHKMIRNS--SALKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFIN------ENTVIMAYLFTTFNAFQGMFIFIFHCALQKKVHKEY----------SKCLRHSYCCSRT----STTSSHGSLKNSALRTNNRYYTGSQTRHAAVHRQ-----------------------------------SRIRRMWNDTVRKQTESSFMAGDINSTPTLN-----------------------------------------------------------------------------------------------------------RGTMGNHLLTNPVLQTRTGSSPYNTLLAET--FTPPSPGVFNSTGTFRDP--------------------------------------------KSTLSKNRDHGGMETLPLN-------------GNFNNSYSLRSVGGSGAPGGSCDFLGGGGGDSPPPLLNPRGSETLGGIR---------RNLSDAAAFEKMIISELVHNNLRGGGGVGGGDRTCGSLARGHGHLGMGRAGGGVEPVIGMEDDEDFRSREARQRTPQDVELLYKALEEP--------------LLLQRAQSVLYQSDPDESESYTADLTESLGHSGHSAQSAAGQGHSGPPDSPARDSLYTSITNLRDSP-YPDSSPE-PLEVVPR--SAQP-PEELYYS--SGRPAIGSRGAPMQTFYQAP-PRRPSTEAHPAPEAPHSEGDGQMQLVTSL--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7G7-4", "uniprot_id": "LPHN_DROME", "id": "A1Z7G7-4", "name": "Latrophilin Cirl", "aln": "---------------MLPTILSISYEHISLDLSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISAAQTSTTTNRPSPPPWVLS---NGPPIFGNGSGLIHPPGVG---------------------------AGAPPPPRLPTLPGVVGISGNPGLFNVPPQHTAVTHSTPSSSTTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQ-----LHHHHNHHGEDTASPTKPSSKLPAGGNATSPSN---TRILTGVGGSGTDDGTLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNINLNAAGMSGGDDESKLFCG----------------PTHARNLYWNMTRVGDVNVQPCP--GGAAGIAKWRCVLMKRIPDSGYDEYDDDISSTTPAPSGGDCLHNSSSCEPPVSMAHKVNQRLRNFEPT----------------------------WHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFP------------DQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGK-GRHIQLSQPITLTLKHLKTENVTNPTCVFWNYIDH----AWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSIFCGFITIFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQTPKVNCYYLLSYGLSLSVVAISLVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMG-------------------ATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAGSTHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRGAGGVPASPSGSLHSRTAAASQVLFYPSYKKTKPGQPTGYPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQ-PEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .: .: :. : **** : :.* .*** : ***** . .**: . .*:* :*.::.::..** :: .* *:*.:. * ******:**** :*:*:. *.. * . . .*: .* * ... :**. . .*: * . ::* . : * :: . *:. : .*: * . : :: . ::*. ..* :* : * *. .: :. : * . .. .*.. * .: : .* .: * :.:. . :.:*: *: . :: . * . . .: . * .. :: *: . *.. . . ... * :: .* *:* ***::* * *:*:: :::. :. .** :: . * . ::.**: :.:::: : : : : ::: . ::** ::.**:* .*** . *.** *:*. :* :.** ** :* .*****:.: . . *: *.* **.*: ..: **: .. *:*. :: : *..* *::** :..* :*. :.* :. :.. * :**:**:**:.* . :: * :*: :*: **: :* ...* **** :: **::** * .:* **:.*:*.******:** : : : : :: ::.* *.:* :.*.: *: ::.* ::: *.:*:..: : *: *****:**::*: : * ::: :** :*:. :*:* *..: * *. : .: .: : *** .* :. **.*: .** :* :. * * * :::: *: ** ..:: : : ::: * *.* . . : :** .:: ::.:*:**. .*. . :::. . : : .* * **:: *::**:*** ::*:::** .**** * . : : *:* . : .: : * . .: : *: :*.:*:* :::.* **: * .. *:.* .::. : .. .* .* : . . :* * * . : ** ::.*.:* . .. ..** *. .* .:..*::* : . .. *... . * . .. ::: :. * *:.:: : * :::. : : :.*. . : .: :.* ..::: .: :.. : . . *:: * * :. * * * . : .. . . **. . ", "identical_positions": 273, "similar_positions": 483, "identity": "14.78%" }, { "cls_id": "homologset.agr.RGD:620769", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D572-1", "uniprot_id": "UBX11_MOUSE", "id": "Q9D572-1", "name": "UBX domain-containing protein 11", "aln": "MSSPLASLSKTRKVPLESESVNPGRRGIRVYGNEDEVDMWNDGQDSEEKISLPSCYGGIGAPVSRQGP--HDSELMASMTRKLQELEQQLQAQNDEMLSKERKILDLEDLVQTLQQHQNNAALQRQEELETQCIQLQRQIGEMERFLSDYGLQWVGEPMDQENSEEKTVSENDERDWMKAKKFWKPGDSFVPPEVDFDKLMASLQDLSEL-VEGEAQVTPVPGGARFRTLEPIPLKVYRNGIMMFDGPFRPFYDPSTQRCLRDILDGFFPSELQRLYPDGVPFKVSDLRNQIYPEDGLGQFPGEGRVVGRQKMRKVTDRVEETSGSRMTAEQFLNRLPKCIIRQGEVIDIRGPIRDTLQNCCPMPARIQEIIVETPALASERQRSQESPDMPMPLLSMLRIKSENGEQAFLLMMWPEDTIGDVRKLLAQARDMDSAAFEILSTFPPTVYQDDTVTLQAAGLVPNATLLLRTRRALLSNP----ISRPGSLP-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R512-1", "uniprot_id": "UBX11_RAT", "id": "Q8R512-1", "name": "UBX domain-containing protein 11", "aln": "MSSPLASLSKTRKVPLESEPVNPGRRGIRIYGDEDEVDMVNDGQDSEEKISLPSCYGGIGR--QGLMI--HDSELLTSMARKLQELEQQLKARNEEMLSKEQKILALEDLVQTLQQHQS--STTREEELETQCIQLQRQVGEMERFLNDYGLQWVGEPMDQENSEGKIISESDERDWMKAKKFWKPGDSIVPPEVDFDRLLSSLQDLSELVVEGEAQVTPVPGGAQFRTLEPIPLKLYRNGIMMFDGPFRPFYDPYTQRCLRDILDGFFPSELQRLYPDGVPFKVSDLRNQVYPEDGLGPFPGEGRVVGRQKIRKVTDRVEETSGSRMTAEKFLNRLPKCVIRQGEVIDIRGPIRDTLQNCCPMPVRIQEIIVETPALASERQRTQESPNMPVPPLSMLRIKSENGEQAFLLMMRPEDTIGDVRNLLAQARDMDSAAFEILSTFPPTVYRDDTVTLQAAGLVPNATLLLRTRRVLPANPSFGTDSGPGSLP-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5T124-1", "uniprot_id": "UBX11_HUMAN", "id": "Q5T124-1", "name": "UBX domain-containing protein 11", "aln": "MSSPLASLSKTRKVPLPSEPMNPGRRGIRIYGDEDEVDMLSDGCGSEEKISVPSCYGGIGAPVSRQVPASHDSELMAFMTRKLWDLEQQVKAQTDEILSKDQKIAALEDLVQTLRPHPAEATLQRQEELETMCVQLQRQVREMERFLSDYGLQWVGEPMDQEDSESKTVSEHGERDWMTAKKFWKPGDSLAPPEVDFDRLLASLQDLSELVVEGDTQVTPVPGGARLRTLEPIPLKLYRNGIMMFDGPFQPFYDPSTQRCLRDILDGFFPSELQRLYPNGVPFKVSDLRNQVYLEDGLDPFPGEGRVVGRQLMHKALDRVEEHPGSRMTAEKFLNRLPKFVIRQGEVIDIRGPIRDTLQNCCPLPARIQEIVVETPTLAAERERSQESPNTPAPPLSMLRIKSENGEQAFLLMMQPDNTIGDVRALLAQARVMDASAFEIFSTFPPTLYQDDTLTLQAAGLVPKAALLLRARRAPKSSLKFSPGPCPGPGPGPSPGPGPGPSPGPGPGPSPCPGPSPSPQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************** **.:********:**:****** .** .******:******** . *****:: *:*** :****::*:.:*:***::** ********: * : *:***** *:*****: ******.**************:** * :** .*****.**********:.*******:*::******** ***::*********::*********:************:***** **********************:************:* ****. *********** ::*. ***** .*******:******* :**********************:*.*****:****:**:**:*:****: * * ******************* *::****** ****** **::****:******:*:***:*********:*:****:**. :. . **. * ", "identical_positions": 365, "similar_positions": 74, "identity": "70.19%" }, { "cls_id": "homologset.agr.RGD:62077", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERS8-1", "uniprot_id": "SEBOX_RAT", "id": "Q9ERS8-1", "name": "Homeobox protein SEBOX", "aln": "------------------------------MASPVEASPG-CASGL---------GPHRRKRTTFSVGQLLELERVFAARPYPDISTREHLAQITHLPEAKIQVWFQNRRAKRIKDRKPGALNARLELPPN-CSLPDTP-----------------------QLSWDPGTPSHPLHS---------TSSAQQTSACPPQTSCLAPILG---PGQS---WSG-AKAAAPWG------TSEVSGVHS-LEQIVP-------------------QTSLGNLSDLIYTSAIVTNVDHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70368-1", "uniprot_id": "SEBOX_MOUSE", "id": "P70368-1", "name": "Homeobox protein SEBOX", "aln": "------------------------------MASPVEASPG-CASGL---------GPHRRKRTTFSVGQLVELERVFAARPYPDISTREHLAQVTHLPEAKIQVWFQNRRAKRIKDRKPGALNSRLELPPNSCSLPDTP-----------------------QLPWDPGTSSHPLHP---------TSSAQYTSACPPQTSCLGPILG---PGQS---WSG-AKVAAPWG------TSGASGIHSSLEQIVP-------------------QTSLGNLSDLIYTSAIVTNVDHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HB31-1", "uniprot_id": "SEBOX_HUMAN", "id": "Q9HB31-1", "name": "Homeobox protein SEBOX", "aln": "------------------------------MPSPVDASSADGGSGL---------GSHRRKRTTFSKGQLLELERAFAAWPYPNISTHEHLAWVTCLPEAKVQVWFQKRWAKIIKNRKSGILSPGSECPQSSCSLPDTL-----------------------QQPWDPQMPGQPPPS---------SGTPQRTSVCR-HSSCPAPGLS---PRQG---WEG-AKAVAPWG------SAGASEVHPSLERATP-------------------QTSLGSLSDLIYALAIVVNVDHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JJ26-1", "uniprot_id": "SEBOX_DANRE", "id": "Q8JJ26-1", "name": "Homeobox protein SEBOX", "aln": "MALFYDQSFDLGLVQKINMETESDFIFNTNMLQFTDVTTKHMLSSPELDRTGHVEGQRKRKRTIFSRAQLSELERAFMITPYPDITLRERLAALTLLPESKIQVWFQNRRARSMKSKKLITPVSR-RSPAKDCTFPATHPDLNLEQSPEANKSLRHHQQSLIRQALNPWPQNRPPISPDLPEILQWANRNSETPGDSSFSSCPSERIQHPFPNQSSSVWQMNCFAAHPEGLKSYCTTSQALYSSVSVDQMIPAHPSSLEEALQRQALTHYPQTSLGDISDLIYKAAVVTNLEEC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .:.:. *. * ::**** ** .** ****.* ***:*: :*:** :* ***:*:*****:* *: :*.:* . . * . *::* * : . :* .:* . :. . *. :** . : * *. *. . .. * * :: . ::: * *****.:***** *:*.*::. ", "identical_positions": 65, "similar_positions": 59, "identity": "22.11%" }, { "cls_id": "homologset.agr.RGD:620770", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P82471-1", "uniprot_id": "GNAQ_RAT", "id": "P82471-1", "name": "Guanine nucleotide-binding protein G(q) subunit alpha", "aln": "MTLESIMACCLSEEAK--------EARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMVRAMDTL-----------------------------------------------------------------KIPYKYEHNKAHAQLVREVDVEKVSAFENPYVD----------------------------------------------AIKSLWN-DPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21279-1", "uniprot_id": "GNAQ_MOUSE", "id": "P21279-1", "name": "Guanine nucleotide-binding protein G(q) subunit alpha", "aln": "MTLESIMACCLSEEAK--------EARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTL-----------------------------------------------------------------KIPYKYEHNKAHAQLVREVDVEKVSAFENPYVD----------------------------------------------AIKSLWN-DPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50148-1", "uniprot_id": "GNAQ_HUMAN", "id": "P50148-1", "name": "Guanine nucleotide-binding protein G(q) subunit alpha", "aln": "MTLESIMACCLSEEAK--------EARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTL-----------------------------------------------------------------KIPYKYEHNKAHAQLVREVDVEKVSAFENPYVD----------------------------------------------AIKSLWN-DPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23625-1", "uniprot_id": "GNAQ_DROME", "id": "P23625-1", "name": "G protein alpha q subunit", "aln": "------MECCLSEEAK--------EQKRINQEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGYIKLVFQNIFMAMQSMIKAMDML-----------------------------------------------------------------KISYGQGEHSELADLVMSIDYETVTTFEDPYLN----------------------------------------------AIKTLWD-DAGIQECYDRRREYQLTDSAKYYLSDLARIEQADYLPTEQDILRARVPTTGILEYPFDLDGIVFRMVDVGGQRSERRKWIHCFENVTSIIFLVALSEYDQILFESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPKQDHAAAKQFVLKKYLACNPDPERQCYSHFTTATDTENIKLVFCAVKDTIMQNALKEFNLG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E9A7-1", "uniprot_id": "Q0E9A7_DROME", "id": "Q0E9A7-1", "name": "Guanine nucleotide-binding protein subunit alpha", "aln": "------MHCCSSTEAM--------EKRRINEEIDKQLRLEKKRSKRELKLLLLGACESGKSTFIKQMRIIHGSGYSDEDKRGYIKLVFQNIFMAMQSMIKAMDML-----------------------------------------------------------------KISYGQGEHSELADLVMSIDYETVTTFEDPYLN----------------------------------------------AIKTLWH-DAGIQECYDRRREYQLTDSTEYFLGDIGRIEQADYLPTNQDILRAREPTFNITVYPFELDGYVLSMVDVAGQRTERRKWIHFFSNVTSIIFLAALSEYDQFMMESENDNRLEESKALFHTIITFEWFKNASIILFLNKMDVLEEKIMYSHLVDYFPEYDGPKQDAYAAREYVLRMFQSISLDTYKKIYSHFTCATDTENIKFVFAAVKDTILQCNLKESNLF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08539-1", "uniprot_id": "GPA1_YEAST", "id": "P08539-1", "name": "Guanine nucleotide-binding protein alpha-1 subunit", "aln": "------MGCTVSTQTIGDESDPFLQNKRANDVIEQSLQLEKQRDKNEIKLLLLGAGESGKSTVLKQLKLLHQGGFSHQERLQYAQVIWADAIQSMKILIIQARKLGIQLDCDDPINNKDLFACKRILLKAKALDYINASVAGGSDFLNDYVLKYSERYETRRRVQSTGRAKAAFDEDGNISNVKSDTDRDAETVTQNEDADRNNSSRINLQDICKDLNQEGDDQMFVRKTSREIQGQNRRNLIHEDIAKAIKQLWNNDKGIKQCFARSNEFQLEGSAAYYFDNIEKFASPNYVCTDEDILKGRIKTTGITETEFNIGSSKFKVLDAGGQRSERKKWIHCFEGITAVLFVLAMSEYDQMLFEDERVNRMHESIMLFDTLLNSKWFKDTPFILFLNKIDLFEEKVKSMPIRKYFPDYQGRVGDAEAGLKYFEKIFLSLN-KTNKPIYVKRTCATDTQTMKFVLSAVTDLIIQQNLKKIGII", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * :: : :* *: *::.*: :*: :.*:******: ******.:**::::* .*:*.::: : :::: : : :*: :: * * .: : .. . * *.*: *:. : *** **. * **::*: * .*:** .*: *::.:: :. .. *: *::*:*: * * .* *:: . : ::*..***:**:**** *..:*:::*: *:*****.:.*.:. **:.** ** *::. **:::..****** *::***: : .***:*:* * *. ::. : : . .. : * : * ****:.:::*:.**.* *:* **: .: ", "identical_positions": 116, "similar_positions": 136, "identity": "24.22%" }, { "cls_id": "homologset.agr.RGD:620771", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2B5P8-1", "uniprot_id": "A0A8M2B5P8_DANRE", "id": "A0A8M2B5P8-1", "name": "Receptor-type tyrosine-protein phosphatase", "aln": "---MMVLFLVSAALIS-----------NSSSHGNLTTESPAPQGSHVLASGLVTS-LLLVIFLLLVAYILRFREQRKDLVTSVDKKLPNGFLEDQE-------------------------------QTVVLLPRSPSPSKRYFPIPLDSLEEEFRLRMADDGKLFREEFNSLPCGFGCGTFEEASREENREKNRYPNILPYDHSRVLLSHIDG--YMGSDYINASYIDGYREKNKFIAAQGPKPETVGDFWRMVWE---HKCATIVMLTNTRERKEEKCYQYWPE--QGCWIYGCVRVAMEDFTVLVDYTIRKFCVQHH-AAEGCRPPRLVTQLHFTSWPDFGVPLS------PIGMLKFLKKVKSVNPAHAGPIIVHCSAGVGRTGTFIVIDAMMDMMHAEGRVDVFGFVSRIRKQRCQLIQTDMQYSFIYQALLEHYLFGDTELDIASLEGHLHKLH--NTHTNMDRVGLEEEFRKLTNVRIMKENMRTGNLPANMRKNRVLQIIPYDFNRVILSMKRGQEFTDYINASFIDGYRQKDYFIATQAPLAHTVQDFWRMVWEWKCHSIVVLTELKEREQEKCVRYWPAEGSVSFGDYVLELKRDTLCET------FSIRDMLLSYAS-----EKQTRLVRQFHFHGWPEIG-IPSDGKGMIDIIAAVQKQQQQSGNNPIVVHCSAGAGRTGTFIALSNILERVKAEGLLD-----------------VFQTVKSLRTQRPHMVQTVEQYDFCYRVVQDFVDIYSDYANFK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9QJB7-1", "uniprot_id": "A0A8M9QJB7_DANRE", "id": "A0A8M9QJB7-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "---MVLVLFLSVTTPQ-----------VTTNATENNHGDPGPFNTHILSILLGLS-VLLLFLGLLTWYCLRLKNQRKAVITAVDKKVPNGILEEQEEYIDVDVDVDMDMDMDEDEDEDDLGWPSEEQQTVVLLPRSPSTSKTYLPIPVDNLEEEYRIRSADDGKLFREEYSSLPGGSIQGTCEEANKEENKEKNRYPNILPYDQSRVILTPMDG--VTCSDYINASYIDGYKDKNKFIAAQGPKQDTTADFWRMIWE---QKSSTIVMLTNLKERKEDKCYQYWPD--QGCWTYGNVRVAVEDFTVLVDYTIRKFCVQYQ-ASDGSKSPRLVTQLHFTSWPDFGVPFS------PIGMLKFLKKVKQVNPSYAGPIVVHCSAGVGRTGTFIVIDAMIDMMHTEQKVDVFGFVSRIREQRSQLIQTDLQYSFVYQALLEYFLYGDTELDVSSLEGHLQKLH--NTNAPLDRVGLEEEFKKLTNMRIMKENMRTGNLPANMKKNRVLQIIPYDFNRVILSMKRGQEFTDYVNASFIDGYRQKDYYIATQGPLVHTVDDFWRMAWEWKCHSIVMLTELQERDQDKCFQYWPSEDSVTYGEFSVEIKGDTLCET------FSLRDLVLTHTP-----EKQTRLVRHFHFHGWPEIG-IPAEGKGMIDIIAAVQKQQQQSGNHPIIVHCSAGAGRTGTFIALSNILERVKAEGLLD-----------------VFQTVKSLRMQRPHMVQTVEQYDFCYRVVQDFVDIFSDYANFK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B2GV87-1", "uniprot_id": "PTPRE_RAT", "id": "B2GV87-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "MEPFCPLLLASFSLSLATAGQGNDTTPTESNWTSTTAGPPDPGTSQPLLTWLLLP--LLLLLFLLAAYFFRFRKQRKAVVNSNDKKMPNGILEEQE------------------------------QQRVMLLSRSPSGPKKYFPIPVEHLEEEIRVRSADDCKRFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHCRVILSQLDG--IPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWE---QRSATIVMLTNLKERKEEKCYQYWPD--QGCWTYGNIRVCVEDCVVLVDYTIRKFCIHPQ-LPDSCKAPRLVSQLHFTSWPDFGVPFT------PIGMLKFLKKVKTLNPSHAGPIVVHCSAGVGRTGTFIVIDAMMDMIHSEQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLEYYLYGDTELDVSSLERHLQTLH--GTATHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEFTDYINASFIDGYRQKDYFMATQGPLAHTVEDFWRMVWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGDITIEIKSDTLSEA------ISIRDFLVTFKQPLARQEEQVRMVRQFHFHGWPEVG-IPTEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLD-----------------VFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49446-1", "uniprot_id": "PTPRE_MOUSE", "id": "P49446-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "MEPFCPLLLASFSLSLARAGQGNDTTPTESNWTSTTAGPPDPGASQPLLTWLLLP--LLLLLFLLAAYFFRFRKQRKAVVSSNDKKMPNGILEEQE------------------------------QQRVMLLSRSPSGPKKFFPIPVEHLEEEIRVRSADDCKRFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHCRVILSQVDG--IPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWE---QRSATIVMLTNLKERKEEKCYQYWPD--QGCWTYGNIRVCVEDCVVLVDYTIRKFCIHPQ-LPDSCKAPRLVSQLHFTSWPDFGVPFT------PIGMLKFLKKVKTLNPSHAGPIVVHCSAGVGRTGTFIVIDAMMDMIHSEQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLEYYLYGDTELDVSSLERHLQTLH--STATHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEFTDYINASFIDGYRQKDYFMATQGPLAHTVEDFWRMVWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGDITIEIKSDTLSEA------ISVRDFLVTFKQPLARQEEQVRMVRQFHFHGWPEVG-IPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLD-----------------VFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23469-1", "uniprot_id": "PTPRE_HUMAN", "id": "P23469-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "MEPLCPLLLVGFSLPLARALRGNETT-ADSNETTTTSGPPDPGASQPLLAWLLLPLLLLLLVLLLAAYFFRFRKQRKAVVSTSDKKMPNGILEEQE------------------------------QQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADDCKQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDG--IPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWE---QKSATIVMLTNLKERKEEKCHQYWPD--QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQ-LPDGCKAPRLVSQLHFTSWPDFGVPFT------PIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHLQTMH--GTTTHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEYTDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGEITIEIKNDTLSEA------ISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIG-IPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLD-----------------VFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25044-1", "uniprot_id": "PTP1_YEAST", "id": "P25044-1", "name": "Tyrosine-protein phosphatase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MAAAPWYIRQRDTDLLGKFKFIQNQEDGRLREATNGTVN--SRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSGNDYINASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWP-----------------------------------------------------------------------------------------------RGGVDDT-----------------------------------------------------------------------------------------------VRIASKWESPG------------------------GANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVG-----------------------------------------------------------------------------PVKTVHHFYFDLWKDMN-KPEEVVPIMELCAHSHSLN--SRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYLNSLSVNQ----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VJ95-1", "uniprot_id": "Q9VJ95_DROME", "id": "Q9VJ95-1", "name": "", "aln": "---------------------------MTAATGGGSSGAGGGKTGKHRSRSSARYDDVEKQQRKSRAIVSIPNTIKLSMLNSGLLSFERIKLEARD------------------------------------ENNSLSKTIPNGPIDIRHFLKLCDLRR--KFPVLYKLEFQTAAKVESNTCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGG--LQDSDYVNASYVDSLLKPNAYIVTQGPVEETVQAYWRMVWQ---ENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIVREEQLANFHIRTFRLYKMNEKQEVTDERLILQFHYTEWYSHSCPFSNALLEFRRRVRLVVGNIIKDEDDMRGPILVHCSDGGGRSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTLEEHIICGKTWFPVSELSDRLKAKARRNSGTKMNEYQAEYDQICKQTPRFTIGDCAGGHRADNREKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKHTLGEFWSLVYDQECSAVVVLCQPPSQSQQYPSFWPNKSKMEKYGPVFSVHYVMSKSYTNIKQWEFKINKKIVSLTEMMAGVKAPTRTVQLFQLTCWPMGHKVPSSTNSLVYLMNMVEIWRNKVDYGPVCVVSPDGRSRAGVYCAANACIEQVIQHGEVD-----------------VFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYVLHFLNKKE--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . : : : : . .* :*: : :* : ** * :.* :.*::.. . . . :*.:*** .* :*:* :. .***:* : . *:**** * . : *: * :.. :: *:: : : .*: : * . .: *: * : * * . :: : . . *: * .. * .*:*.: * . :. . : : * * :* :* ::*:. :: : * . : ", "identical_positions": 46, "similar_positions": 90, "identity": "5.97%" }, { "cls_id": "homologset.agr.RGD:620772", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01750-1", "uniprot_id": "T2FB_RAT", "id": "Q01750-1", "name": "General transcription factor IIF subunit 2", "aln": "-------------------------------------------MAERG-------ELDLTGAKQNTGVWLVKVPKYLSQQWAKAP--GRGEVGKLRIAK-------------NQG-RTEVSFTLN----------------------------------------EDLANIHDIGGKPASVSAPREHPFVLQSVG--GQTLTVFTESSSDKLSLEGIVVQRAECRP-AASENYMKLKR-----LQIEESSKPVRLSQQADKVVTTNYKPVANHQYNIEYERKKKEDG--KRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVGYLKEILKEIGIQNVKGIHKNTWELKPEYRHYQTEEKSD-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0A0-1", "uniprot_id": "T2FB_MOUSE", "id": "Q8R0A0-1", "name": "General transcription factor IIF subunit 2", "aln": "-------------------------------------------MAERG-------ELDLTGAKQNTGVWLVKVPKYLSQQWAKAS--GRGEVGKLRIAK-------------NQG-RTEVSFTLN----------------------------------------EDLANIHDIGGKPASVSAPREHPFVLQSVG--GQTLTVFTESSSDKLSLEGIVVQRAECRP-AASENYMKLKR-----LQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDG--KRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVGYLKEILKEIGIQNVKGIHKNTWELKPEYRHYQTEEKSD-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13984-1", "uniprot_id": "T2FB_HUMAN", "id": "P13984-1", "name": "General transcription factor IIF subunit 2", "aln": "-------------------------------------------MAERG-------ELDLTGAKQNTGVWLVKVPKYLSQQWAKAS--GRGEVGKLRIAK-------------TQG-RTEVSFTLN----------------------------------------EDLANIHDIGGKPASVSAPREHPFVLQSVG--GQTLTVFTESSSDKLSLEGIVVQRAECRP-AASENYMRLKR-----LQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDG--KRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVVYLKEILKEIGVQNVKGIHKNTWELKPEYRHYQGEEKSD-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41900-1", "uniprot_id": "T2FB_DROME", "id": "P41900-1", "name": "General transcription factor IIF subunit 2", "aln": "-------------------------------------------MSKEDKEKTQIIDKDLDLSNAGRGVWLVKVPKYIAQKWEKAP--TNMDVGKLRINK-------------TPGQKAQVSLSLTPAVLA-------------------------------LDPEEKIPTEHILDVSQVTKQTLGVFSHMAPSDGK-ENSTTSAAQPDNEKLYMEGRIVQKLECRP-IADNCYMKLKL-----ESIRKASEPQRRVQPIDKIVQN-FKPVKDHAHNIEYRERKKAEG--KKARDDKNAVMDMLFHAFEKHQYYNIKDLVKITNQPISYLKEILKDVCDYNMKNPHKNMWELKKEYRHYKTEEKKEEEHKSGSSDSE------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41896-1", "uniprot_id": "T2FB_YEAST", "id": "P41896-1", "name": "Transcription initiation factor IIF subunit beta", "aln": "MSSGSAGAPALSNNSTNSVAKEKSGNISGDEYLSQEEEVFDGNDIENNETKVYEESLDLDLERSNRQVWLVRLPMFLAEKWRDRNNLHGQELGKIRINKDGSKITLLLNENDNDSIPHEYDLELTKKVVENEYVFTEQNLKKYQQRKKELEADPEKQRQAYLKKQEREEELKKKQQQQKRRNNRKKFNHRVMTDRDGRDRYIPYVKTIPKKTAIVGTVCHECQVMPSMNDPNYHKIVEQRRNIVKLNNKERITTLDETVGVTMSHTGMSMRSDNSNFLKVGREKAKSNIKSIRMPKKEILDYLFKLFDEYDYWSLKGLKERTRQPEAHLKECLDKVATLVKKGPYAFKYTLRPEYKKLKEEERKATLGELADEQTGSAGDNAQGDAEADLEDEIEMEDVV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. . ** . . ****::* :::::* . ::**:** * . . : .: *. * : . . . . : : .:. .* : * : :. : * . * :: .:.: .. : . : .: .. *: ::* .. * * *: ::* ** *::::*:.:*.* . *.** :*** *..: *. : : *: **:: : **:. ", "identical_positions": 44, "similar_positions": 86, "identity": "11.0%" }, { "cls_id": "homologset.agr.RGD:620773", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14630-1", "uniprot_id": "APOM_RAT", "id": "P14630-1", "name": "Apolipoprotein M", "aln": "-MFHQVWAALLYLYGLLFNSMNQCPEHSQLMTLGMDDKETPEPHLGLWYFIAGAAPTMEELATFDQVDNIVFNMAAGSAPRQLQLRATIRTKNGVCVPRKWTYHLTEGKGNTELRTEGRPDMKTDLFSISCPGGIMLKETGQGYQR-FLLYNRSPHPPEECVEEFQSLTSCLDFKAFLVTPRNQEACPLSSK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1R3-1", "uniprot_id": "APOM_MOUSE", "id": "Q9Z1R3-1", "name": "Apolipoprotein M", "aln": "-MFHQVWAALLSLYGLLFNSMNQCPEHSQLTALGMDDTETPEPHLGLWYFIAGAASTTEELATFDPVDNIVFNMAAGSAPRQLQLRATIRTKSGVCVPRKWTYRLTEGKGNMELRTEGRPDMKTDLFSSSCPGGIMLKETGQGYQR-FLLYNRSPHPPEKCVEEFQSLTSCLDFKAFLVTPRNQEACPLSSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95445-1", "uniprot_id": "APOM_HUMAN", "id": "O95445-1", "name": "Apolipoprotein M", "aln": "-MFHQIWAALLYFYGIILNSIYQCPEHSQLTTLGVDGKEFPEVHLGQWYFIAGAAPTKEELATFDPVDNIVFNMAAGSAPMQLHLRATIRMKDGLCVPRKWIYHLTEG--STDLRTEGRPDMKTELFSSSCPGGIMLNETGQGYQR-FLLYNRSPHPPEKCVEEFKSLTSCLDSKAFLLTPRNQEACELSNN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NXE0-1", "uniprot_id": "A0A8M1NXE0_DANRE", "id": "A0A8M1NXE0-1", "name": "", "aln": "MIAATLWGLVSSVMGLFYVGLQVMVPCLPPAPLSTSVINT-DEYTGTWYFVAAAVWDEDDLKTLQTTDSIVLQIQKNSD-STLKVTETMRIGDACLKNVTNYYALPATSPFLFREDFDTIAVIWDGKYINCPTCIIMLYVGEDEEMNTFLFSRDEKTTEEAIQEFKSKTECLLMEDMWRAPLKNGYCKVDDSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*. : . *:: .: .*. . : : : * ***:*.*. ::* *:: .*.**::: .* *:: *:* .. . * *. . . : : .** *:: .*:. : :*:.*. :..*:.::**:* *.** : : :* :: * :... ", "identical_positions": 35, "similar_positions": 68, "identity": "18.13%" }, { "cls_id": "homologset.agr.RGD:620774", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05909-1", "uniprot_id": "PTPRG_MOUSE", "id": "Q05909-1", "name": "Receptor-type tyrosine-protein phosphatase gamma", "aln": "MRRLLEPCWW-ILFLKITSSVLHYVVCFPALTEGYVGTLQESRQDSSVQIRRRKASGDPYWAYSGAYGPEHWVTSSVSCGGSHQSPIDILDHHARVGDEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFILRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQALNDRVVSKSAVRDAWNHDLADFLDNPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKE-KTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTRIFQGTRIVKTGVPTASPASSADMAPISSGSSTWTSSGIPFSFVSMATGMGPSSSGSQATVASVVTSTLLAGLGFGGGGISSFPSTVWPTRLPTASAASKQAGRTVLATTEALASPGPDVHSAPSKDSEGTEEGEKEEKSESEDGEREHEEE-EKDSEKKEKSEATHTAAESDRTAPAPTPSSPHRTAAEGGHQTIPGRRQDHSAPATDQPG---HVAPDLDPLVDTATQVPPTATEEHYSGSDPRRPEMPSKKPMSRGDRFSEDSKFITVNPAEKNTSGMLSR---PSPGRMEWIIPLIVVSALTFVCLVLLIAVLVYWRGCNKIKSKGFPRRSREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNE--SVPIIPIPDDMEAIPVKQFGKHIGELYSNSQHGFSEDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIIMITNLVEKGRRKCDQYWPTENTEEYGNIIVTLKSTKVHACYTVRRLSVRNTKVKKGQKGNPKGRQNERTVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPDMGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETAVSSSQLHSYVNSILIPGVGGKTRLEKQFKLITQCNAKYVECFSAQKECNKEKNRNSSVVPAERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLIS------------------------------------------------------------TKENGNGPMTGDKNGAVLTAEESDPAESMESLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LP13-1", "uniprot_id": "F1LP13_RAT", "id": "F1LP13-1", "name": "Receptor-type tyrosine-protein phosphatase gamma", "aln": "MRRLLEPCWW-ILFLKITSSVLHYVVCFPALTEGYVGTLQESRQGSSVQIRRRKASGDPYWAYSGAYGPEHWVTSSVSCGGSHQSPIDILDHHARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFVLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQALNDRVVSKSAVRDAWNHDLADFLDNPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKE-KTFTKDSDKDLKATISHISPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTRIFQGTRIVKTGVPTASPASSADMAPISSGSSTWTSSGIPFSFVSMATGMGPSSSGSQATVASVVTSTLLAGLGFGGGGISSFPSTVWPTRLPTASAASKQAGRPVLATTEALASPGPDGDSAPTKDGEGAEEGEKEEKSESEDGEREQEEE-EKDSEKKEKSEATHTAAESDQTAPAPTPSSPHRTAQEGGHQTIPGHRQDHSAPVTDQPG---HVDPGLDTLVDTATQVPPTATEEHYSGSDPKRPEMPSKKPISRGDRFSEDSKFITVNPAEKNTSGMISR---PSPGRMEWIIPLIVVSALTFVCLVLLIAVLVYWRGCNKIKSKGFPRRSREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNE--SIPIIPIPDDMEAIPVKQFGKHIGELYSNSQHGFSGDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIIMITNLVEKGRRKCDQYWPTENTEEYGNIIVTLKSTEVHACYTVRRFSVRNTKVKKGQKGNPKGRQNERTVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPDMGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSSQLHSYVNSILIPGVGGKTRLEKQFKLITQCNAKYVECFSAQKECNKEKNRNSSVVPAERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALARDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLVS------------------------------------------------------------TKENGNGPMTGDKNGAVLTAEESDPAESMESLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23470-1", "uniprot_id": "PTPRG_HUMAN", "id": "P23470-1", "name": "Receptor-type tyrosine-protein phosphatase gamma", "aln": "MRRLLEPCWW-ILFLKITSSVLHYVVCFPALTEGYVGALHENRHGSAVQIRRRKASGDPYWAYSGAYGPEHWVTSSVSCGGRHQSPIDILDQYARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSINGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFVLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQRLHDRVVSKSAVRDSWNHDMTDFLENPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKE-KTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTRIFQGTRIVKTGVPTASPASSADMAPISSGSSTWTSSGIPFSFVSMATGMGPSSSGSQATVASVVTSTLLAGLGFGGGGISSFPSTVWPTRLPTAASASKQAARPVLATTEALASPGPDGDSSPTKDGEGTEEGEKDEKSESEDGEREHEEDGEKDSEKKEKSGVTHAAEERNQTEPSPTPSSPNRTA-EGGHQTIPGHEQDHTAVPTDQTGGRRDAGPGLDPDMVTSTQVPPTATEEQYAGSDPKRPEMPSKKPMSRGDRFSEDSRFITVNPAEKNTSGMISR---PAPGRMEWIIPLIVVSALTFVCLILLIAVLVYWRGCNKIKSKGFPRRFREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNE--SIPIIPIPDDMEAIPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSNQLHSYVNSILIPGVGGKTRLEKQFKLVTQCNAKYVECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFIYKAMLSLVS------------------------------------------------------------TKENGNGPMTVDKNGAVLIADESDPAESMESLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QQH6-1", "uniprot_id": "A0A8M1QQH6_DANRE", "id": "A0A8M1QQH6-1", "name": "protein-tyrosine-phosphatase", "aln": "MWRLRGPCRLGMLCLTLSALLIQPISCHPAS------HVETVRRGSSANQRERRASGEPYWAYSGTYGPRRWASAYPECGERNQSPVDILDPETQVSQECQELTLDGFETKSSNRTTMKNTGKTVSIVLKNDYFVRGAGLPGRFKAEKVEFHWGSTNGSAGSEHSINGKKFPVEMQIYFYNSDDFDSLSTAIKERRIIAAMAVFFQVATKDNIAAEPIIAGLKRVVHHEKETNLGSFILRDLLPSSLGSYYRYTGSLTTPPCSKVVEWIIFSRPVYLSYHQLEAFYSIFTTEQQDHVKSVDYLRNNHRPIQDLDSRRIFKSALMDAW---MPETMASAADTETSRVCSSIPDNMKLHPLNRTALVLTWDRPSAVYHPPIVGFLVSYSWVKDEMPFE-KTFTQSSEHSTRAVITLVSPDVLYLFRVQALCQRDQRSDFSQTLLFKANTTRIFEGTRIVKTGMPTVSPASSADMAPISSGSSTWTSAGLPFSFVSMATGMGPPSSGGQATVASVVTSTLLAGLGFSGSVISSLPGSFWPTHSTNTGPSPTQHP----ATPTAENSPSED-----STDTQNKLEEEEEHKKEDDEEEEEEEEEEEQRDEEKKKKGKDVTVKDKKQTVQKPTAPIP------------TSKHRDRERPDAESST---LTPAEVEEQVSGATERPDAEDSSKATWQDDNDMQIPSSSTESSKLSDEEKANWPYYINTERNSISTVSRDSVSSSSRMEWIIPLMVVSALTLLCLIMLLAVLVYWR-----------------------------RFFQTAHFYIEDRNSPRVIHND--SFPIISTADDLEAMPVRQFIKHIMELHSNNRHGFSQEFDEVQHCTSEMKITAEHSNHPENKHKNRYINIVAYDHSRVKLQQLPGKDSKHSDYINANYVDGYKRARAYIAAQGPLKSTFEDFWRMIWEQNTTVIVMITNLVEKGRRKCDQYWPSENSEVYGNIMVTLKSTKVYAYYTLRHFIVRNSKLKKGQKG----RQNERLVLQYHYTQWPDMGVPEYTLPVLKFISRSTVTHASSTGPVLVHCSAGVGRTGTYIVIDSMLKQIKDRGSVNVLGFLKHIREQRNYLVQTEEQFIFIHDALMEAVLSKDTEVSAWQLHTYTNSLLTPSPTGHTRMDKHFKLLTQCNAHLAECLSGQKECNKEKNRTSAVLPTERARVALSPLPGLKGTDYINASYIMGYYRSNEFIITQHPLPHTTTDFWRMIWDHNAQVIVMLPDNLGLTEDEFVYWPSREEPMNCIAFTVTLINTDRLCLSNEEQLIIHDFILEATQDDYVLEVRHFQCPNWPDPDASISSTFELINIIKEEAMTRDGPTIVHDEFGAVSAGTFCALTTLSQQLENESAVDVYQVAKMINLMRPGVFTEIEHYHYLYQAMLSLVS------------------------------------------------------------SKDFRFGFNYMDKFAG--KADESNQAESMESLV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35832-1", "uniprot_id": "PTP99_DROME", "id": "P35832-1", "name": "Tyrosine-protein phosphatase 99A", "aln": "---MPRPQHHALLRAMLKLLLFASIAEHCAT------ALPTNSSNSPSSPSPFTAASLPPTTASSSSSP-----AVISTSSSDRNLADLVNPEAETTGSGWESLETEFNLATTVDSSTQKTEK-EPVLGTVATSIEQQDQPPDVPATTLAFANAFPVPVAGEMGNGNG------------NYNDATPPYAAVDDN--------YVPSKPQNLTILDVSANSITMSWHPPKN-----------QNGAIAGYHVFH------------------------IHDNQTGVEIVKNSRNSVETLIHFELQNLRPYTDYR-------VIVKAFTTKNEGEPSDQIAQRTDVGGPSAPAIVNLTCHSQESITIRWRRPYEFYN--TIDFYIIKTRLAGQDTHR-DIRINASAKELETAMILQNLTTNSYYEVKVAAATFSVINPKKIVLGKFSESRIIQLQPNCEKLQPLLR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QSHNDYNLAVLVGIIFSCFGIILIIMAFFLWS----------------------------RKCFHAAYYYLDDPPHHPNAPQVDWEVPVKIGDEIRAAVPVNEFAKHVASLHADGDIGFSREYEAIQNECISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQK-KNLDYINANFIDGYQKGHAFIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWPKDGVETYGVIQVKLIEEEVMSTYTVRTLQIKHLKLKKKKQCN-----TEKLVYQYHYTNWPDHGTPDHPLPVLNFVKKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNIVNVFGFLRHIRAQRNFLVQTEEQYIFLHDALVEAIASGETNLMAEQVEELKN--------CTPYLEQQYKNIIQFQPKDIHIASAMKQVNSIKNR-GAIFPIEGSRVHLTPKPGEDGSDYINASWLHGFRRLRDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLSSLDDINFAQ--FWPDEATPIESDHYRVKFLNK-----TNKSDYVSRDFVIQSIQDDYELTVKMLHCPSWPEMSNPNSIYDFIVDVHERCNDYRNGPIVIVDRYGGAQACTFCAISSLAIEMEYCSTANVYQYAKLYHNKRPGVWTSSEDIRVIYNILSFLPGNLNLLKRTALRTEFEDVTTATPDLYSKICSNGNVPQHVILQQQQLHMLQLQQQHLETQQQQQQQQQQQQQQQQQTALNETVSTPSTDTNPSLLPILSLLPPTVAPLSSSSSTTPPPPSTPTPQPPQTIQLSSHSPSDLSHQISSTVANAGSPATASAGATPTTPMTPTVPPTIPTIPSLASQNSLTLTNANFHTVTNNAADLMEHQQQQMLALMQQQTQLQQQYNTHPQQHHNNVGDLLMNNADNSPTASPTITNNNHITNNNVTSAAATDAQNLDIVG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40048-1", "uniprot_id": "PTP3_YEAST", "id": "P40048-1", "name": "Tyrosine-protein phosphatase 3", "aln": "--------------------------------------MKDSVDCPSILPTDRTSVLSETSTLVG-------------------SSSHVYSRHAPMNSYHNSMNSNIYHSPKASSPLVSYKTSSPVLLKRATAPVLPSFKP---KEQRYNKPQGCSLITAVELG---------------------KIIETLPDEK------VLLLDVRPFTEHAKSIITNSIHVCLP-----------------STLLRRKNFT---------------------------FSKLLDNLTPSEQSVLKSKLAIDN-----------------LRIIIYDSTANQTESSVSLPCYGIASKLIEFDTNVKKTVSILMCGFPQFKILFPDHINTNTFNSDCISSAEPKSPKTNLMNSLHNTAPHMTATTPLSSPQMNLKLKVPDDSRSDHSNFSSSPSPRNVLSD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPMSSSSPISALFKFQLPAPQTNINQMFKFS----------------------------------------------------------------QNEEIMGLETYLSAVNIKEEHERWYNNDSAKKSLQNFQFPKNQNSLEKDTNKDKLGFQIRYENLSKNYEKEVIDSVIPEWFQHLMSIPKIELVSQFQKLDFLEKRRLNHSVSFRKKENSFILEKPSSYPEQLTSTSSSTIMPPKFPDVNKVQKRSHSQPIFTQYSKYKSMLSLESDSDSESDD---------VIISSGVELGAKNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYINANYLSLPRFSVEQNSSFQTTTTTTRRVRYIATQAPMPSTVHD-FYTCILNNGVPLVLSLTNDFEN-----------GIEKCYRYWQEGNYNGIHVKLLEKKILKMPSTTSMRKNTMGTQNSSLYSAGVQG-NSSNYSTDNDNDNDNNNNNNNNSNIAVTAAACDDDDDDDDDAILIRKILLTYHDQEKPYELLQIQVKNWPDLGTLLNPISILQAINVKNHIIDTLFARNYYQNDQLPTILVHCSAGCGRTGTLCTIDSILSNFEMFEMLQK--EFVKLKYPAKLFDPISWTINIFRKQRISMVQNINQFIFIYDCLLFYFRLRLDDITERTDGDGSNKD-------------------------------------------------------------NISLSALIEQIEKLEILQTFVDDKLKELPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : : . . .: . : . :. .: . . . . :: : * . . * . : .:. . . . .: .:: : . . .. ..:. . : : . .. . . : : : .: . . . * :. . : . .:: : .: . : : . . .: . : : :. : : : .:: : . : : :. . .:. ::.. .:..*:: *:: : . .. : : : : : : :: : ::. :: :. *: ... . : . : : *: : . .. :. * .: . . :* . .. * *.::. * ..** : : . . : : .::. :** : .: . . : . * ::: :: : : : . *: . . . :: .* .* : * * . . .: .::. . *.: : ::: : : . : . : * .: : :. . :: * . .:*. . . ::. : :. .: .: . :. .: : . . :: * : . . :. . . : : : . . ", "identical_positions": 27, "similar_positions": 267, "identity": "1.59%" }, { "cls_id": "homologset.agr.RGD:620775", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQS5-1", "uniprot_id": "SC5D_RAT", "id": "Q9EQS5-1", "name": "Lathosterol oxidase", "aln": "MDLVLSAADYYFFT-------------------------------------------------------PYVYPAT-------WPEDNIIRQTVSLLVVTNLGAYILYFFCATLSYYFVYDHSLMKHPQFLKNQVSREIMFTVKSLPWISIPTVSLFLLELRGYSKLYDDIGDFPNGWIHLIMSVISFLFFTDMLIYWIHRGLHHRLLYKHIHKPHHIWKIPTPFASHAFHPVDGFLQSLPYHIYPFVFPLHKVVYLGLYVLVNVWTISIHDGDFRVPQIFRPFINGSAHHTDHHMLFDYNYGQYFTLWDRIGGSFKHP--SSFEGK---GPHSYVKNMTEKESNSLAENGCKSKKLC-NGEFTKNE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88822-1", "uniprot_id": "SC5D_MOUSE", "id": "O88822-1", "name": "Lathosterol oxidase", "aln": "MDLVLSAADYYFFT-------------------------------------------------------PYVYPAT-------WPEDNIIRQTISLLIVTNLGAYILYFFCATLSYYFVYDHSLMKHPQFLKNQVSREIVFTVKSLPWISIPTVSLFLLELRGYSKLYDDIGDFPNGWIHLMVSVVSFLFFTDMLIYWIHRGLHHRLVYKRIHKPHHIWKIPTPFASHAFHPVDGFLQSLPYHIYPFVFPLHKVVYLGLYVLVNVWTISIHDGDFRVPQILRPFINGSAHHTDHHMFFDYNYGQYFTLWDRIGGSFKHP--SSFEGK---GPHSYVKNMTEKESNSFAENGCKGKKVG-NGEFTKNK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75845-1", "uniprot_id": "SC5D_HUMAN", "id": "O75845-1", "name": "Lathosterol oxidase", "aln": "MDLVLRVADYYFFT-------------------------------------------------------PYVYPAT-------WPEDDIFRQAISLLIVTNVGAYILYFFCATLSYYFVFDHALMKHPQFLKNQVRREIKFTVQALPWISILTVALFLLEIRGYSKLHDDLGEFPYGLFELVVSIISFLFFTDMFIYWIHRGLHHRLVYKRLHKPHHIWKIPTPFASHAFHPIDGFLQSLPYHIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQILQPFINGSAHHTDHHMFFDYNYGQYFTLWDRIGGSFKNP--SSFEGK---GPLSYVKEMTEGKRSSHSGNGCKNEKLF-NGEFTKTE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32353-1", "uniprot_id": "ERG3_YEAST", "id": "P32353-1", "name": "Delta(7)-sterol 5(6)-desaturase ERG3", "aln": "MDLVLEVADHYVLDDLYAKVLPASLAANIPVKWQKLLGLNSGFSNSTILQETLNSKNAVKECRRFYGQVPFLFDMSTTSFASLLPRSSILREFLSLWVIVTIFGLLLYLFTASLSYVFVFDKSIFNHPRYLKNQMAMEIKLAVSAIPWMSMLTVPWFVMELNGHSKLYMKIDYENHGVRKLIIEYFTFIFFTDCGVYLAHRWLHWPRVYRALHKPHHKWLVCTPFASHSFHPVDGFLQSISYHIYPLILPLHKVSYLILFTFVNFWTVMIHDGQYLS---NNPAVNGTACHTVHHLYFNYNYGQFTTLWDRLGGSYRRPDDSLFDPKLRDAKETWDAQVKEVEHFIKEVEGDDNDRIYENDPNTKKNN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** .**:*.: *::: : *...*:*: :** ::..: . :**:* *:*** **:*:::::**::****: ** ::*.::**:*: **. *::*:.*:***: .:. * .*::. .:*:**** :* ** ** :*: :***** * : ******:***:******:.*****:::***** ** *: :**.**: ****:: .* :**:* ** **: *:*****: *****:***::.* * *: * . :: ::.* : :* ...:: *. **.: ", "identical_positions": 130, "similar_positions": 101, "identity": "35.33%" }, { "cls_id": "homologset.agr.RGD:620776", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28828-1", "uniprot_id": "PTPRM_MOUSE", "id": "P28828-1", "name": "Receptor-type tyrosine-protein phosphatase mu", "aln": "MRTLGTCLVTLAGLLLTAAGETFSGGCLFDEPYSTCGYSQADEDDFNWEQVNTLTKPTSDPWMPSGSFMLVNTSGKPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNAAPGLLNVYVKVNNGPLGNPIWNISGDPTRTWHRAELAISTFWPNFYQVIFEVVTSGHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAGQFATFQCSAIGRTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMICTEGGVGISNYAELVVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYGYQVGGQEQVREEVSWDTDNSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELTVQTDEDLPGAVPTESIQGSAFEEKIFLQWREPTQTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATN---QFTTKISAPSMPAYEFETPLNQTDNTVTVMLKPAQSRGAPVSVYQIVVEEERPRRTKKTTEILKCYPVP-IHFQNASILNSQYYFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPHKSYRIYYQAASRANGETKIDCVRVATK-------------------------GAVTPKPVPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKRKLAKKRKETMSSTRQEMTVMVNSMDKSYAEQGTNCDEAFSFMGTHNLNGRSVSSPSSFTMKTNTLSTSVPNSYYPD-------------ETHTMASDTSSLAQPHTYKKREAADVPYQTGQLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYDHSRVRLQM------------LEGD--NNSDYINGNYI----------------DGYHRPNHYIATQGPMQETIYDFWRMVWHENTAS---IIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIDTELLAEYVIRTFAVEKRGIHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPNAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCGDTSIPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDGESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQLCPQYWPENGVHRHGPIQVEFVSADLEEDIISRIFRIYNASRPQDGHRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K8V0-1", "uniprot_id": "A0A0G2K8V0_RAT", "id": "A0A0G2K8V0-1", "name": "protein-tyrosine-phosphatase", "aln": "MRTLGTCLVTLAGLLLTAAGETFSGGCLFEEPYSTCGYSQADDDDFNWEQVNTLTKPTSDPWMPSGSFMLVNTSGKPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNAAPGLLNVYVKVNNGPLGNPIWNISGDPTRTWHRAELAVSTFWPNFYQVIFEVVTSGHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAGQFATFQCSAIGRTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVRYCYQVGGQEQVREEVSWDMDNSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELTVQTDEDLPGAVPTESIQGSAFEEKIFLQWREPTQTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATN---QFTTKISAPSMPAYEFETPLNQTDNTVTVLLKPAQSRGAPVSVYQIVVEEERPRRTKKTTEILKCYPVP-IHFQNASILNSQYYFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPHKSYRIYYQAASRANGETKIDCVRVATKAAIIVTQLTTPYIRIAPAAGDGQLTGAVTPKPVPEPEKGTDHTVKIAGVIAGILLFVIIFLGVVLVMKKRKLAKKRKETMSSTRQEMTVMVNSMDKSYAEQGTNCDEAFSFMDTHNLNGRSVSSPSSFTMKTNTLSTSVPNSYYPDPFVPTAILVPINDETHTMASDTSSLAQPHTYKKREAADVPYQTGQLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYDHSRVRLQM------------LEGD--NSSDYINGNYI----------------DGYHRPNHYIATQGPMQETVYDFWRMVWYENTAS---IIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIDTELLAEYVIRTFAVEKRGIHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPNAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCGDTSIPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDGESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPTQLCPQYWPENGVHRHGPIQVEFVSADLEEDIISRIFRIYNASRPQDGHRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNAG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28827-1", "uniprot_id": "PTPRM_HUMAN", "id": "P28827-1", "name": "Receptor-type tyrosine-protein phosphatase mu", "aln": "MRGLGTCLATLAGLLLTAAGETFSGGCLFDEPYSTCGYSQSEGDDFNWEQVNTLTKPTSDPWMPSGSFMLVNASGRPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNSPPGLLNVYVKVNNGPLGNPIWNISGDPTRTWNRAELAISTFWPNFYQVIFEVITSGHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAGQFATFQCSAIGRTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKEPPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYCYQVGGQEQVREEVSWDTENSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELIVQTDEDLPGAVPTESIQGSTFEEKIFLQWREPTQTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATN---QFTTKISAPSMPAYELETPLNQTDNTVTVMLKPAHSRGAPVSVYQIVVEEERPRRTKKTTEILKCYPVP-IHFQNASLLNSQYYFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPYKSYRIYFQAASRANGETKIDCVQVATK-------------------------GAATPKPVPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKRKLAKKRKETMSSTRQEMTVMVNSMDKSYAEQGTNCDEAFSFMDTHNLNGRSVSSPSSFTMKTNTLSTSVPNSYYPD-------------ETHTMASDTSSLVQSHTYKKREPADVPYQTGQLHPAIRVADLLQHITQMKCAEGYGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYDHSRVRLQT------------IEGD--TNSDYINGNYI----------------DGYHRPNHYIATQGPMQETIYDFWRMVWHENTAS---IIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVIRTFAVEKRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDGESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQLCPQYWPENGVHRHGPIQVEFVSADLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25044-1", "uniprot_id": "PTP1_YEAST", "id": "P25044-1", "name": "Tyrosine-protein phosphatase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAPWYIRQRDTDLLGKFKFIQNQEDGRLREATNGTVNSRWS-LGVSIEPRNDARNRYVNIMPYERNRVHLKT------------LSGNDYINASYVKVNVP----------------GQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWP---------------------------------------------------------------------------------------RGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVG---PVKTVHHFYFDLWKDMNKPEE------------VVPIMELCAHSHSLNSRGNP------------------------------------------------------------IIVHCS--------------------AGVGRTG--------------------------------------TFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQR----------MKMVQTKDQFLFIYHAAKYLNSLSVNQ---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40048-1", "uniprot_id": "PTP3_YEAST", "id": "P40048-1", "name": "Tyrosine-protein phosphatase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKDSVDCPSILPTDRTSVLSETSTLVGSSSHVYSRHAPMNSYHNSMNSNIYHSPKASSPLVSYKTSSPVLLKRATAPVLPSFK--------------------------PKEQRYNKPQGCSLITAVELGKIIETLPDEKVLLLDVRPFTEHAKSIITNSIHVCLPSTLLRRKNFTFSKLLDNLTPSEQSVLKSKLAIDNLRIIIYDSTANQTESSVSLPCYGIASKLIEFDTNVKKTVSILMCGFPQFKILFPDHINTNTFNSDCISSAEPKSPKTNLMNSLHNTAPHMTATTPLSSPQMNLKLKVPDDSRSDHSNFSSSPSPRNVLSDSPMSSSSPISALFKFQLPAPQTNINQMFKFSQNEEIMGLETYLSAVNIKEEHERWYNNDSAKKSLQNFQFPKNQNS------------------------------------------------------------LEKDTNKDKLGFQIRYENLSKNYEKEVIDSVIPEWFQHLMSIPKIELVSQFQKLDFLEKRRLNHSVSFRKKENSFILEKP--------------------------------SSYPEQLTSTSSSTIMPPKFPDVNKVQKRSHSQPIFTQYSKYKSMLSLESDSDSESDDVIISSGVELGAKNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYINANYLSLPRFSVEQNSSFQTTTTTTRRVRYIATQAPMPSTVHDFYTCILNNGVPL---VLSLTNDFENGIEKCYRYWQEGNYNGIHVKLLEKKILKMP--------------------------------------------------------------STTSMRKNTMGTQNSSLYSAGVQGNSSNYSTDNDNDNDNNNNNNNNSNIAVTAAACDDDDDDDDDAILIRKILLTYHDQEKPYELLQIQVKN-----WPDLGTLLNPISILQAINVKNHIIDTLFAR-------------------------------------------NYYQNDQLPTILVHCS--------------------AGCGRTG----TLCTIDSILSNFEMFEMLQKEFVKLKYPAKLFDPISWTINIFRKQRISMVQNINQFIFIYDCLLFYFRLRLDDITERTDGDGSNKDNISLSALIEQIEKLEILQTFVDDKLKELPQ------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : . :. :.. : . :*** :*:.*::.** *: .: .*:: * . *****.* .* :*: : :: :* .* . ** :** * . . * . . : * : :. .. . : *.* * : : . :. :: :.: : **: * * * . :. . : * :. . : : . : : * . . ", "identical_positions": 37, "similar_positions": 77, "identity": "2.42%" }, { "cls_id": "homologset.agr.RGD:620777", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63259-1", "uniprot_id": "PTPRN_RAT", "id": "Q63259-1", "name": "Receptor-type tyrosine-protein phosphatase-like N", "aln": "---------------------------------------------------------------------------------------------------------------------------MRRPRRPGGPAG---------CGGSEGSGGLRLLVCLLLLSGRPGGCSAISAHGCLFDRRLCS-HLEVCIQDGLFGQCQAGVGQARPLLQVTSPVLQR---LQGVLRQLMSQGLSWHDDLTQYVISQEMERIPRLRPPEPHPRDRSGSVPRRAGPAGELLSQGNPTGSSPAVQG-LSRPPGDGNGAGVGSPLSSLQ-AELLPPLLEHLLMPPQPPHPS---------------------------------------------------------------LTYEPALLQPYLFQQFGSRDGSRGSESASGVV--GHLAKAEDPVLFSRSLSKAILGTHSGHSFGDLTGPSPAQLFQDSGLLYMAQELPVPGRARAPRLPEEGGSSRAEDSSE-----GHEEEVLGGHGEKSPPQAVQADVSLQRLAAVLAGYGVELRQLTPEQLSTLLTLLQLL----------------PKGTGRHLGGAVN-GGADVKKTIEEQMQRG-DTADARPPTPLLPGHPTASSTSIKVRQVLSPGFPEPPKTSSPLGISAVLLEKKSPLGQSQPTVVGQPS------ARPSAEEYGYIVTDQKPLSLVAGVKLLEILAEHVHMTSGSFINISVVGPAVTFRIRHNEQN----LSLADVTQQAGLVKSELEAQTGLQILQTGVG------QREESAAVLPRQAHGISPMRSLLLTLVALAGVAGLLVALAVALCMRHHSKQRDKERLAALGPEGAHGDTTFEYQDLCRQHMATKSLFNR------AEGQPEP-------------SRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQANMDISTGHMILAYMEDHLRNRDRLAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGSSLYHVYEVNLVSEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGR-SCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60673-1", "uniprot_id": "PTPRN_MOUSE", "id": "Q60673-1", "name": "Receptor-type tyrosine-protein phosphatase-like N", "aln": "---------------------------------------------------------------------------------------------------------------------------MRRPRRPGG------------SGGSGGSGGLRLLVCLLLLSGRPGGCSAISAHGCLFDRRLCS-HLEVCIQDGLFGQCQAGVGQARPLLQVTSPVLQR---LQGVLRQLMSQGLSWHDDLTQHVISQEMERIPRLRPPEPHPRDRSGLVPRKPGPAGELLTQGNPTGSSPAAQG-FPRPAGGRSWG--GSPLSSLQ-AELLPPLLEHLLMPPQPPHPA---------------------------------------------------------------LTYEPALLQPYLFHQFGSRDGSRGSESSSGVVGVGHLSKAEGPALFSRSASKAILGTHSGHSFGDLTGPSPAQLFQDSGLLYMAQELPVPGRARAPRLPENGGN-RAEDSSE-----GHEEEVLGGRGEKSPPQAAQPELSLQRLTAVLAGYGVELRQLTPEQFSTLLTLLQLL----------------PKGTGRNLEGAVNVGGADVKKTIQ-QMQRG-DPAEALPPTPSLPGYLTASPASSEVQQVLSPGFPEPPHTPSPLGSSSVLLEKKSPLGQSQPTVVGRPS------ARPSAEEYGYIVTDQKPLSLVAGVRLLEILAEHVHMSSGSFINISVVGPAVTFRIRHNEQN----LSLADVTQQAGLVKSELEAQTGLQILQTGVG------QREEAAEVLPRQAHGISPMRSVLLTLVALAGVAGLLVALAVALCMRHHSRQRDKERLAALGPEGAHGDTTFEYQDLCRQHMATKSLFNR------AEGQPEP-------------SRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQANMDISTGHMILAYMEDHLRNRDRLAKEWQALCAYQAEPNTCAAAQDESNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGSSLYHVYEVNLVSEHIWCEDFLVRSFYLKNLQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGR-SCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16849-1", "uniprot_id": "PTPRN_HUMAN", "id": "Q16849-1", "name": "Receptor-type tyrosine-protein phosphatase-like N", "aln": "---------------------------------------------------------------------------------------------------------------------------MRRPRRPGG---------------LGGSGGLRLLLCLLLLSSRPGGCSAVSAHGCLFDRRLCS-HLEVCIQDGLFGQCQVGVGQARPLLQVTSPVLQR---LQGVLRQLMSQGLSWHDDLTQYVISQEMERIPRLRPPEPRPRDRSGLAPKRPGPAGELLLQDIPTGSAPAAQHRLPQPPVGKGGAGASSSLSPLQ-AELLPPLLEHLLLPPQPPHPS---------------------------------------------------------------LSYEPALLQPYLFHQFGSRDGSRVSEGSPGMVSVGPLPKAEAPALFSRTASKGIFGDHPGHSYGDLPGPSPAQLFQDSGLLYLAQELPAPSRARVPRLPEQGSSSRAEDSPE-----GYEKEGLGDRGEKPASPAVQPDAALQRLAAVLAGYGVELRQLTPEQLSTLLTLLQLL----------------PKGAGRNPGGVVN-VGADIKKTMEGPVEGR-DTAELPARTSPMPGHPTASPTSSEVQQVPSPVSSEPPKAARPP-VTPVLLEKKSPLGQSQPTVAGQPS------ARPAAEEYGYIVTDQKPLSLAAGVKLLEILAEHVHMSSGSFINISVVGPALTFRIRHNEQN----LSLADVTQQAGLVKSELEAQTGLQILQTGVG------QREEAAAVLPQTAHSTSPMRSVLLTLVALAGVAGLLVALAVALCVRQHARQQDKERLAALGPEGAHGDTTFEYQDLCRQHMATKSLFNR------AEGPPEP-------------SRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQANMDISTGHMILAYMEDHLRNRDRLAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGASLYHVYEVNLVSEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGR-SCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BD60-1", "uniprot_id": "A0A8M2BD60_DANRE", "id": "A0A8M2BD60-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------MRSAR-------------------------LWMLVCLATACCQLG---TGDKYGCLFDEGLCS-RGEICWDDELFGQCLAER-QERFRYRVTAVLLDR---LQSLLQTLMKEGLTWQDDVTQSVIKKELSKVPKIP-----------------------LSSGTKNGPSIESQS---------------GSTNQLN-SKQAHPYMDYMIVD--PPQSS---------------------------------------------------------------LHMQS--LDPYSYQRYGYQDEE---ERSLNLVEKGRYPASSSRVRGNPPVPPSLD--KDDQLLQDLMTLLLSSPAQPSSRHRVAAPHSTSSFFQDLDFPLEYKDYNKDTFSQDERISSQREPKKGPQKYGSFSAHSAAGTSQQGLNELLLQHGFDLNHLNPEEMERLFSVLQFLQNE-------------PPNNQRKSEAKDSSAPPKVMKITEGEMTHVVEKASSPASNSSSPPLKPGPQTSPKSPGSPGASKDNSIPTGASVLGPLTLKQEEGPLGKGALSVQPGKN------KTKIKEEFGYIVTNQSPLNLSDGVHLLKTLAERIHLTTDSFINISVVGPAVTFRVLPNSQN----LTASEISEKTVAQKNLLETETGLKVLQAGVG------EKSE-GHALPVATRVRDNTQWVFLMFVGVACLGGLLVGALTIACLRTHARHLASGKLG-LGPEAGN-VTHYEYQDLCRQHMAAKSSLGRQDCGVGAAGGAGPGAVGGGGGGGTDTSRVSSVSSQFSDAPQPSPSSHSSTPSWCEEPAQSNMDISTGHMILAYMEDHLKNKDRLLKEWEALCSYQAEPSTISAAQSESNIKKNRCSDAVPYDHSRVKLKAEINPSRTDYINASTIIEHDPRMPAYIATQGPLSHTISDFWQMVWESGCTVIVMMTALVEDGEKQCDRYWPDEGSSLYHIYEVNLVSEHIWCNDFLVRSFYLKNVQTQETRTLTQFHFLSWPAQGIPTSTRPLLDFRRKVNKCYRGR-SCPIIVHCSDGTGRTGTYILIDMVLNRMAKGVKEIDIAATLEHIRDQRPGMVRTKDQFEFALTAVAEEVNAILKALPQ----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPV8-1", "uniprot_id": "Q9VPV8_DROME", "id": "Q9VPV8-1", "name": "", "aln": "MPAVGTSCGVPIIMARNVQQRQQHPCTTTEEPKHQRARGTAGHQESATGECQQFWSKQRPPFDQQQQQEDQDPEQDPQQHPSTPQESVHHHRSPRQHELLHHQRKVPPTLPARGRHLISEGARRREVRGCGAGGGGLLCCSLDALSRPAKLLQFGVLLLILLLATHGDLAQAEGNVGCQFVRTLCIPHSEVCYDDNIFGKCIPTTGVDVEDIEKTPLTEDQSRVLATMLEELQGAGLGWDHPYVQCRIQGSLFSLQRQQQLPPNLCANLAPTPPEFGDPASALAYVRFTPPEPEAELDYYEQPAGPAQFYPALRKKQVRESDADDMYLNRMLQDRRRLRHDPSELEHFGKMDGHGQSTQLDAPSIMDAFLDTERQRIEREQQLAAAEQDADRRAEQNRLELYQILAASEPDPQPYQRKPAAQPNAMDQLEAIVEQQQQRELKEQQEQAKAPVYVPPEEVNESSELYFPDNFAPFKRARGRSRGGLAEEVEDEQPKRSFFRELAGEQGLVQEPPLRFRHVETEVDATPELVKRRPASFKQLDPYDVSLQQQEMAFESGLLRNSLTPLEEEAMLASNSFPRQAKSQRVYTEGGLLLMPQDEQDTDGMQADEPENVKQSLLANMLGFARHERLDVKKPGPLLGPPSLGSAELSNQLETEKAHKQKGHGNKEVLPAHIKGNDEDDAHKKKKVMKQQHSAEDHAPHTVDTEYVHVFVKNPIDSWNDGQRIMKELEQILHMQG-YFSYLTVQQHEVSFRVNSNNPERKTAGDVARTINENRGVKNNIQRRVGFYVLHAGVGDVIKDLQDPSVSSSRIELAEQGPDVTHIMAYMFAGAGAAAVIVIFVTLILIKRHDRKRDK-LGGLQSGIAGAETCSKDYQELCRARMAGKAGGGGNSTGGAAGGGSNE------------PAPSGRITSLSKENEGRPPSSRSSTSSWSEEPALTNMDISTGHMVLSYMEDHLRNKGRLQREWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILKALPANTSGEKRELDKDPVVGGGSSSTTTKEPLKEDKAQEAAEEEAPTSSSKAAAAAKKEKEKDKDKEEKQAKDQAKVAEPRTPAKSAKQAKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : :*: : . : . : . ** * . ** : *:* :* :**:* . *. :: * :*. * ** *.. .* *. .: : : * . . : . :. :. :: :: : * . :** : . : * . . . * : . . :. : . : . . : *. . *.* : . ::: .: :. . .: : : .. .. :: : . : :. .: .* *: ::...: . * :::: * : :*: * ::* ::**: *. : : :: *. :: ..*: :*::*** : . . :. :: :.. * ..::* . :: * :: . . . .. :**:*** :** *: . * * . : . ::* .: .***:***.**.**** :*********:*:******:*:.** :**:*** *:***.: :*. ** :****:*: *: ... **:***.* :**** ***:*:****. *::.****:**.*..*** : * *:* * ****:**:.:**:***:********:*:*********::*.****:********* * *:.::.**********.**** ****:** * *:****.***:*:**:** **.:**********:****.*:* :::****.* ******:******* ", "identical_positions": 259, "similar_positions": 235, "identity": "19.43%" }, { "cls_id": "homologset.agr.RGD:620778", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4T2-1", "uniprot_id": "SIAH2_RAT", "id": "Q8R4T2-1", "name": "E3 ubiquitin-protein ligase SIAH2", "aln": "MSRPSSTGPSANKPCSKQPPPPQTPHAPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGAGGGAGPVSP----------QHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06986-1", "uniprot_id": "SIAH2_MOUSE", "id": "Q06986-1", "name": "E3 ubiquitin-protein ligase SIAH2", "aln": "MSRPSSTGPSANKPCSKQPPPPQTPHAPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGAGGGADPVSP----------QHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43255-1", "uniprot_id": "SIAH2_HUMAN", "id": "O43255-1", "name": "E3 ubiquitin-protein ligase SIAH2", "aln": "MSRPSSTGPSANKPCSKQPPP-QPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSP----------QHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYL3-1", "uniprot_id": "SIAH2_DANRE", "id": "Q7SYL3-1", "name": "E3 ubiquitin-protein ligase Siah2", "aln": "MSRPSSAGGAAGGLGAGKAGG--SKHGGSGGTTASAAAAAAAAAAAAAAAAAAAGVSGSVAGSGTVPAAAVALPVAALPGQSPELTALFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGPLTPSIRNLAMEKVASTLPFPCKYSSAGCLLSLHHSEKPEHEEVCEFRPYTCPCPGASCKWQGSLEEVMPHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTSIAHLFADNGNLGINVTISMC--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P21461-1", "uniprot_id": "SINA_DROME", "id": "P21461-1", "name": "E3 ubiquitin-protein ligase sina", "aln": "MS--NKINPKRREPTAAAAGAGATGVATN---TSTSTGSSSAGNTSSANTSSSSSSSLSSAGGGDAGMSA-------------DLTSLFECPVCFDYVLPPILQCSSGHLVCVSCRSKLTCCPTCRGPLAN-IRNLAMEKVASNVKFPCKHSGYGCTASLVYTEKTEHEETCECRPYLCPCPGASCKWQGPLDLVMQHLMMSHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYDGHQQFFAIVQLIGSRKEAENFVYRLELNGNRRRLTWEAMPRSIHEGVASAIHNSDCLVFDTSIAQLFADNGNLGINVTISLV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .. . : . . . ..::: ::*. ::* .:::: * . .*.* :. :**:******************.:***** .**.**:*******.*: *********** : ****:: ** :* ::**.***: ** *** ************.*: ** *** :************************************************:********* ***:**:****.**************** *****:***:** *********:**:*************** ", "identical_positions": 208, "similar_positions": 55, "identity": "62.09%" }, { "cls_id": "homologset.agr.RGD:620779", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88488-1", "uniprot_id": "PTPRQ_RAT", "id": "O88488-1", "name": "Phosphatidylinositol phosphatase PTPRQ", "aln": "------------------MMDFHFSFLFLL-----------------------IGTSESQVDVSSSFDGTGYDITLSSVSATTYSSPVSRTLATNVTKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYVVKYKEVCPWMQTAYTRARAKPDSLEVLLTNLNPGTTYEIKVAAENNAGIGVFSDPFLFQTAESAPGKVVNLTVEALNYSAVNLIWYLPRQPNGKITSFKISVKHARSGIVVKDVSLRVEDILSGKLPECNENSESFLWSTTSPSPTLGRVTPTVRTTQSSSTAARSKISSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDSTIVRTPESVPEGPPQNCIMGNVTGKAFSISWDPPTIVTGKFSYRVELYGPSGRILDNSTKDLRFAFTHLTPFTMYDVYVAAETSAGVGPKSNLSVFTPPDVPGAVFDLQIAEVEATEIRITWRKPRQPNGIISQYRVKVSVLETGVVLENTLLTGQDESISNPMSPEIMNLVDPMIGFYEGSGEMSSDLHSPASFIYNSHPHNDFPASTRAEEQSSPVVTTRNQYMTDITAEQLSYVVRRLVPFTEHTISVSAFTIMGEGPPTVLTVRTREQVPSSIQIINYKNISSSSILLYWDPPEYPNGKITHYTIYATELDTNRAFQMTTVDNSFLITGLKKYTRYKMRVAASTHVGESSLSEENDIFVRTPEDEPESSPQDVQVTGVSPSELRLKWSPPEKPNGIIIAYEVLYQNADTLFVKNTSTTDIIISDLKPYTLYNISIRSYTRLGHGNQSSSLLSVRTSETVPDSAPENITYKNISSGEIEISFLPPRSPNGIIQKYTIYLKRSNSHEARTINTTSLTQTIGGLKKYTHYVIEVSASTLKGEGIRSRPISILTEEDAPDSPPQNFSVKQLSGVTVMLSWQPPLEPNGIILYYTVYVWDKSSLRAINATEASLVLSDLDYNVDYGACVTASTRFGDGNARSSIINFRTPEGEPSDPPNDVHYVNLSSSSIILFWTPPVKPNGIIQYYSVYYQNTSGTFVQNFTLLQVTKESDNVTVSARIYRLAIFSYYTFWLTASTSVGNGNKSSDIIHVYTDQDIPEGPVGNLTFESISSTAIHVSWEPPSQPNGLVFYYLSLNLQQSPPRHMIPPLVTYENSIDFDDLEKYTDYIFKITPSTEKGFSETYTTQLHIKTEEDVPDTPPIINTFKNLSSTSILLSWDPPLKPNGAILGYHLTLQGPHANHTFVTSGNHIVLEELSPFTLYSFFAAARTMKGLGPSSILFFYTDESAPLAPPQNLTLINYTSDFVWLTWSPSPLPGGIVKVYSFKIHEHETDTVFYKNISGLQTDAKLEGLEPVSTYSVSVSAFTKVGNGNQYSNVVEFTTQESVPEAVRNIECVARDWQSVSVRWDPPRKTNGIIIHYMITVGGNSTKVSPRDPTYTFTKLLPNTSYVFEVRASTSAGEGNESRCDISTLPETVPSAPTNVAFSNVQSTSATLTWTKPDTIFGYFQNYKITTQLRAQKCREWEPEECIEHQKDQYLYEANQTEETVHGLKKFRWYRFQVAASTNVGYSNASEWISTQTLPGPPDGPPENVHVVATSPFGINISWSEPAVITGPTFYLIDVKSVDDDDFNISFLKSNEENKTTEINNLEVFTRYSVVITAFVGNVSRAYTDGKSSAEVIITTLESVPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIRVYQALVYREDDPTAVQIHNFSIIQKTDTSIIAMLEGLKGGHTYNISVYAINSAGAGPKVQMRITMDIKAPARPKSKPIPIRDATGKLLVTSTTITIRMPICYYNDDHGPIRNVQVLVAETGAQQDGNVTKWYDAYFNKARPYFTNEGFPNPPCIEGKTKFSGNEEIYVIGADNACMIPGNEEKICNGPLKPKKQYLFKFRATNVMGQFTDSEYSDPIKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFVRIRQKQKEGGTYSPRDAEIIDTKFKLDQLITVADLELKDERLTRLLSYRKSIKPISKKSFLQHVEELCTNSNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIADVSLPGSDYINASYVSGYLCPNEFIATQGPLPGTVGDFWRMVWETRTKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDIQIDWTIRDLKIERHGDCMTVRQCNFTGWPEHGVPENTTPLIHFVKLVRTSRAHDTTPMVVHCSAGVGRTGVFIALDHLTQHINNHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKGGHQPVCFVNYSTLQKMDSLDAMEGDVELEWEETTM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C5E4-1", "uniprot_id": "PTPRQ_MOUSE", "id": "P0C5E4-1", "name": "Phosphatidylinositol phosphatase PTPRQ", "aln": "-------------------MDFLFFFLFSL-----------------------IGTSESQVDVSGSFDDTVYDITLSSISATTYSSPVSRTLATNVSKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYVVKYKEVCPWMQTAYTRVRAKPDSLEVLLTNLNPGTTYEIKVAAENSAGIGVFSDPFLFQTAESAPGKVVNLTVEALNYSAVNLIWYLPRQPNGKITSFKISVKHARSGIVVKDVSIKVEDLLSGKLPECNENSDSFLWSTTSPSPTLSRATPPLRTTHLSNTLARNKISSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDSTIVRTPESVPEGPPQNCITGNVTGKAFSISWDPPAIVTGKFSYRVELYGPTGRILDNSTKDLRFVFTHLTPFTMYDVYVAAETSAGVGPKSNLSVFTPPDVPGAVFDLQIVEVEATEIRVSWRKPRQPNGIISQYRVKVSVLESGVILENTLLTGQDEYINNPMTPEIMNLVDPMIGFYEGSGEMSSDLHSLASFIYNSHPH-DFPARTRVEDQRSPVVATRNQYMTDIAAEHLSYVIRRLVPFTEHTISVSAFTVMGEGPPTVLTVRTREQVPSSIQIINYKNISSSSILLYWDPPEYPNGKITHYTIYAMELDTNRAFQMTTVDNSFLITGLKKYTRYKMRVAASTHVGESSLSEENDLFVRTPEDEPESSPQDVKVTDVSPSELSLTWSPPEKPNGIIIAYEVFYQNADALFVKNTSTTNITLSDLKPYTLYNISIQSYTRLGHGNQSSSLLSVRTSETVPDSAPENITYKNISSEEIEIFFLPPRSPNGIIQKYTIYLKRSNSHEARTIETTSLTLTIGGLKKYTHYVIEVSASTLKGEGVRSMPISILTEEDAPDSPPQNFSVKQLSGVTVMLSWQPPLEPNGIILYYTVYVWDKVSLKTINATEVSLELSDLDYHADYSAYVTASTRFGDGKTRSSVINFRTPEGEPSDPPKDVHYVNLSSSSIILFWTPPVKPNGIIQYYSVYYQNTSSTFVQNFTLLEVTQEPGNVTVSARIYKLAVFSYYTFWLTASTLVGNGNKSSDVIHVYTDQDIPEGGVGNLTYESLSSTAINVSWTPPSQPNGLVFYYVSLNLQQSPPRHRRPPLTTYENSIYFDNLEKYTDYIFKITPSTEKGFSETYTAQLHIKTEEDVPDTPPIINTFKNLSSTSILLSWDPPLKPNGAILSYHLTLQGTHANRTFVTSGNHIVLEELSPFTLYSFLAAARTMKGLGPSSILFFYTDESAPLAPPQNLTLINYTSDFVWLTWSPSPLPGGIVKVYSFKIHEHETDTVFYKNISGFQTDAKLAGLEPVSTYSISVSAFTKVGNGNQFSNVVKFTTQESVPDAVQNIACVARDWQSVSVMWDPPRKANGIIIHYMITVEGNSTKVSPRDPMYTFTKLLANTSYIFEVRASTSAGEGNESQCNVSTLPETVPSVPTNTAFSNVQSTSVTLRWIKPDTILGYFQNYKITTQLRAQKCREWEPEECVEHQEVQYLYEANQTEDTVRGLKKFQWYRFQVAASTNAGYGNASSWISTQTLPGPPDGPPENVRVVATSPFGINISWNEPAIITGPTFYLIDVKSVDNDNFNISFVKSNEENKTTEINDLEVFTRYSVVITAFVGNVSGAYTDGKSSAEVIITTLESVPKDPPNNMTFQKIPDEVTKFQLSFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTDTSVIAMLEGLKGGHTYNISVYAINSAGAGPKVQMRITMDIKAPARPKTKPIPIHDATGKLLVTSTTITIRMPICYYNDDHGPIRNVQVLVAEAGAQQDGNVTKWYDAYFNKARPYFTNEGFPNPPCIEGKTKFSGNEEIYVIGADNACMIPGNEEKICNGPLKPKKQYLFKFRATNVMGQFTDSEYSDPIKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPRDAEIIDTKFKLDQLITVADLELKDERLTRLLSYRKSIKPVSKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIADVSIPGSDYINASYVSGYLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDILITKLMEDIQIDWTIRDLKIERHGDCMTVRQCNFTGWPEHGVPENTTPLIHFVKLVRTSRAHDATPMVVHCSAGVGRTGVFIALDHLTQHIHDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKGGHQPVCFVNYSTLQKMDSLDAMEGDVELEWEETTM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UMZ3-1", "uniprot_id": "PTPRQ_HUMAN", "id": "Q9UMZ3-1", "name": "Phosphatidylinositol phosphatase PTPRQ", "aln": "MKKVPIKPEQPEKLRAFNISTHSFSLHWSLPSGHVERYQVDLVPDSGFVTIRDLGGGEYQVDVSNVVPGTRYDITISSIS-TTYTSPVTRIVTTNVTKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYIVKYKEVCPWMQTVYTQVRSKPDSLEVLLTNLNPGTTYEIKVAAENSAGIGVFSDPFLFQTAESAPGKVVNLTVEAYNASAVKLIWYLPRQPNGKITSFKISVKHARSGIVVKDVSIRVEDILTGKLPECNENSESFLWSTASPSPTLGRVTPPSRTTHSSSTLTQNEISSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDSTIVRTPESVPEGPPQNCVTGNITGKSFSILWDPPTIVTGKFSYRVELYGPSGRILDNSTKDLKFAFTNLTPFTMYDVYIAAETSAGTGPKSNISVFTPPDVPGAVFDLQLAEVESTQVRITWKKPRQPNGIINQYRVKVLVPETGIILENTLLTGNNEYINDPMAPEIVNIVEPMVGLYEGSAEMSSDLHSLATFIYNSHPDKNFPARNRAEDQTSPVVTTRNQYITDIAAEQLSYVIRRLVPFTEHMISVSAFTIMGEGPPTVLSVRTRQQVPSSIKIINYKNISSSSILLYWDPPEYPNGKITHYTIYAMELDTNRAFQITTIDNSFLITGLKKYTKYKMRVAASTHVGESSLSEENDIFVRTSEDEPESSPQDVEVIDVTADEIRLKWSPPEKPNGIIIAYEVLYKNIDTLYMKNTSTTDIILRNLRPHTLYNISVRSYTRFGHGNQVSSLLSVRTSETVPDSAPENITYKNISSGEIELSFLPPSSPNGIIKKYTIYLKRSNGNEERTINTTSLTQNIKVLKKYTQYIIEVSASTLKGEGVRSAPISILTEEDAPDSPPQDFSVKQLSGVTVKLSWQPPLEPNGIILYYTVYVWNRSSLKTINVTETSLELSDLDYNVEYSAYVTASTRFGDGKTRSNIISFQTPEGAPSDPPKDVYYANLSSSSIILFWTPPSKPNGIIQYYSVYYRNTSGTFMQNFTLHEVTNDFDNMTVSTIIDKLTIFSYYTFWLTASTSVGNGNKSSDIIEVYTDQDIPEGFVGNLTYESISSTAINVSWVPPAQPNGLVFYYVSLILQQTP-RHVRPPLVTYERSIYFDNLEKYTDYILKITPSTEKGFSDTYTAQLYIKTEEDVPETSPIINTFKNLSSTSVLLSWDPPVKPNGAIISYDLTLQGPNENYSFITSDNYIILEELSPFTLYSFFAAARTRKGLGPSSILFFYTDESVPLAPPQNLTLINCTSDFVWLKWSPSPLPGGIVKVYSFKIHEHETDTIYYKNISGFKTEAKLVGLEPVSTYSIRVSAFTKVGNGNQFSNVVKFTTQESVPDVVQNMQCMATSWQSVLVKWDPPKKANGIITQYMVTVERNSTKVSPQDHMYTFIKLLANTSYVFKVRASTSAGEGDESTCHVSTLPETVPSVPTNIAFSDVQSTSATLTWIRPDTILGYFQNYKITTQLRAQKCKEWESEECVEYQKIQYLYEAHLTEETVYGLKKFRWYRFQVAASTNAGYGNASNWISTKTLPGPPDGPPENVHVVATSPFSISISWSEPAVITGPTCYLIDVKSVDNDEFNISFIKSNEENKTIEIKDLEIFTRYSVVITAFTGNISAAYVEGKSSAEMIVTTLESAPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTNTFVIAMLEGLKGGHTYNISVYAVNSAGAGPKVPMRITMDIKAPARPKTKPTPIYDATGKLLVTSTTITIRMPICYYSDDHGPIKNVQVLVTETGAQHDGNVTKWYDAYFNKARPYFTNEGFPNPPCTEGKTKFSGNEEIYIIGADNACMIPGNEDKICNGPLKPKKQYLFKFRATNIMGQFTDSDYSDPVKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPQDAEIIDTKLKLDQLITVADLELKDERLT---------RPISKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIADASVPGSDYINASYISGYLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDVQIDWTIRDLKIERHGDCMTVRQCNFTAWPEHGVPENSAPLIHFVKLVRASRAHDTTPMIVHCSAGVGRTGVFIALDHLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKGSNQPICFVNYSALQKMDSLDAMEGDVELEWEETTM", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : : * :* .* *****. . .* ****:**:* ***:***:* ::***:***********************************:************.**:.*:**************************.***************************** * ***:*********************************::***:*:**********:******:******.*.**. ***: *.* ::.:*******************************************************: **:***:*** ****:***************:***********:*.**:**********:*******.*****:****************:.***:*::*::*:*********.****** * *:*::********::* *.:**:***:*:*:**:*:****.******** *:*******. :*** .*.*:* ****:*****:***:**:****:********* *******:*********:****:******:********************************* *********:**:*************:*********************:****.***********:* .*:..*: *.****************:*:* *:*::******:* : :*:*:******::****:***** *************************** ***: **** ******:**********.:* ***:***** .* *****:*:************:** ****************:*********** *********************:: **::**.**.** ******:.:*.* **********::**.:*.*:**** *****:**:*.************** *************:***.**:***** :**:: .*:***: * :*::************ *********:*.********** *****:**:*****:*** **:*********:** ***:* ** ***.***.** **:********:***********:***:**:********:*.*************:*******:******:.*.*****.: * :*:**.*:*:************:***** ****************.************ *******.*************************::******::*:*** *********: ************:****:********:.*:*: *:* .**** * ****:*:**** :**:** *******:* *** ***.****:*:**********:** *.:*********.*** ***:*****.** * :****:*****************:***.***:*:*: ******: **:** *****:***********.**.***.****:*************:*******.*.***.***:***** *********:*:*****:******** **::**:***********.**:* **.:******:*:*****.**********************:***********:*******************:******:* :*******************:********* **************:** ** **********************.******:******:*:***:***************************** *************:*************:*********************:*******:****:***********************************.**************:********:******************* :*:***************.**************************************************.*:**********:*******************************:**********************************:*******:**************************.*********::**********:*****:***:***********************::******************************************.:**:******:***********************", "identical_positions": 1915, "similar_positions": 285, "identity": "81.73%" }, { "cls_id": "homologset.agr.RGD:62078", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49242-1", "uniprot_id": "RS3A_RAT", "id": "P49242-1", "name": "Small ribosomal subunit protein eS1", "aln": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQND---EVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGGSS---GKTTGDETGAKVERADGYEPPVQESV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61247-1", "uniprot_id": "RS3A_HUMAN", "id": "P61247-1", "name": "Small ribosomal subunit protein eS1", "aln": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQND---EVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGSSS---GKATGDETGAKVERADGYEPPVQESV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97351-1", "uniprot_id": "RS3A_MOUSE", "id": "P97351-1", "name": "Small ribosomal subunit protein eS1", "aln": "MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQND---EVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGGSS---GKAAGDETGAKVERADGYEPPVQESV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PBY1-1", "uniprot_id": "RS3A_DANRE", "id": "Q6PBY1-1", "name": "Small ribosomal subunit protein eS1", "aln": "MAVGKNKRLTKGGKKGAKKKIVDPFSKKDWYDVKAPAMFNIRNLGKTLVTRTQGTRIASDGLKGRVFEVSLADLQND---EVAFRKFKLVTEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRTNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSVGKDIEKACQSIYPLHDVYVRKVKMLKKPKFELGKLMELHGEGGSTSAAAKPAEGDTGAKVERADGYEPPIQESV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P55830-1", "uniprot_id": "RS3A_DROME", "id": "P55830-1", "name": "Small ribosomal subunit protein eS1", "aln": "MAVGKNKGLSKGGKKGGKKKVVDPFSRKDWYDVKAPNMFQTRQIGKTLVNRTQGQRIASDYLKGRVFEVSLADLQKDIDPERSFRKFRLIAEDVQDRNVLCNFHGMDLTTDKYRSMVKKWQTLIEAIVEAKTVDGYLLRVFCIGFTAKDQQSQRKTCYAQQSQVRKIRARMTDIITNEVSGADLKQLVNKLALDSIAKDIEKSCQRIYPLHDVYIRKVKVLKKPRFDVSKLLELHGDGGGKS--VEAVVSSEGAVIDRPEGYEPPVQEAV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23248-1", "uniprot_id": "RS3A2_YEAST", "id": "P23248-1", "name": "Small ribosomal subunit protein eS1B", "aln": "MAVGKNKRLSRG-KKGLKKKVVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKNASDALKGRVVEVCLADLQGS--EDHSFRKVKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTREVQNSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHGEGSGE---------EKGKKVS---GFKDEVLETV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P33442-1", "uniprot_id": "RS3A1_YEAST", "id": "P33442-1", "name": "Small ribosomal subunit protein eS1A", "aln": "MAVGKNKRLSKG-KKGQKKRVVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKSASDALKGRVVEVCLADLQGS--EDHSFRKIKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTKEVQGSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHGEGSGE---------EKGKKVT---GFKDEVLETV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* *::* *** **::****::*:*:*:*** *: *::*****.:: * : *** *****.**.***** . : :***.:* .::**.:* * ******:* ** ***:****:*** * .** *.*:**:*.:.** * :. :: .*** .::* ** : :*:*.**. * ::..** : : *:**:: : *:**:::.:****:**:*:*::. *: ***:*.. . * : *:: : *:*", "identical_positions": 121, "similar_positions": 83, "identity": "44.81%" }, { "cls_id": "homologset.agr.RGD:620780", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62132-1", "uniprot_id": "PTPRR_MOUSE", "id": "Q62132-1", "name": "Receptor-type tyrosine-protein phosphatase R", "aln": "MRRAVGFPALCLLLNLHAAGCFSRNNDHFLAIRQKKSWKPVFIYDHSQDIKKSLDIA-QEAYKHNYHSPSEVQISKHHQIINSAFPRPAYDPSLNLLAESDQDLEIENLPIPAANVIVVTLQMDITKLNITLLRIFRQGVAAALGLLPQQVHINRLIEKKNQVELFVSPGNRKPGETQALQAEEVLRSLNVDGLHQSLPQFGITDVAPEKNVLQGQHEADKIWSKEGFYAVVIFLSIFIIIVTCLMIIYRLKERLQLSLRQDKEKNQEIHLSPIARQQAQSEAKTTHSMVQPDQAPKVLNVVVDPQGQCTPEIRNSTSTSVCPSPFRMKPIGLQERRGSNVSLTLDMSSLGSVEPFVAVSTPREKVAMEYLQSASRVLTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNITDSLSTYINANYIRGYSGKEKAFIATQGPMINTVNDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVTGVTECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASEGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRVDRGGMVQTSEQYEFVHHALCLFESRLSPETVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08617-1", "uniprot_id": "PTPRR_RAT", "id": "O08617-1", "name": "Receptor-type tyrosine-protein phosphatase R", "aln": "MRRAVGFPALCLLLNLHAAGCFSRNNDHFLAIRQKKSWKPMFIYDHSQDIKKSLDIA-QEAYKHNYPAPSEVQISKRHQIVDSAFPRPAYDPSLNLLAASGQDLEIENLPIPAANVIVVTLQMDIDKLNITLLRIFRQGVAAALGLLPQQVHINRLIEKKSQIELFVSPGNRKPGEPQALQAEEVLRSLNVDVLRQSLPQFGSIDVSPEKNVLQGQHEADKIWSKEGFYAVVIFLSIFIIIVTCLMIIYRLKERLQLSFRQDKEKNQEIHLSPIALQQAQSEAKAAHSMVQPDQAPKVLNVVVDPQGQCTPEIRNTASTSVCPSPFRMKPIGLQERRGSNVSLTLDMSSLGNVEPFVAVSTPREKVAMEYLQSASRVLTSPQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNITDPLSTYINANYIRGYSGKEKAFIATQGPMINTVNDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVIGVNECDNYTIRNLVLKRGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASEGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRVDRGGMVQTSEQYEFVHHALCLFESRLSPETVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15256-1", "uniprot_id": "PTPRR_HUMAN", "id": "Q15256-1", "name": "Receptor-type tyrosine-protein phosphatase R", "aln": "MRRAVCFPALCLLLNLHAAGCFSGNNDHFLAINQKKSGKPVFIYKHSQDIEKSLDIAPQKIYRHSYHSSSEAQVSKRHQIVNSAFPRPAYDPSLNLLAMDGQDLEVENLPIPAANVIVVTLQMDVNKLNITLLRIFRQGVAAALGLLPQQVHINRLIGKKNSIELFVSPINRKTGISDALPSEEVLRSLNINVLHQSLSQFGITEVSPEKNVLQGQHEADKIWSKEGFYAVVIFLSIFVIIVTCLMILYRLKERFQLSLRQDKEKNQEIHLSPITLQPALSEAKTVHSMVQPEQAPKVLNVVVDPQGRGAPEIKATTATSVCPSPFKMKPIGLQERRGSNVSLTLDMSSLGNIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAETVQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ***************** ********.**** **:***.*****:****** *: *:*.* :.**.*:**:***::**************** ..****:******************: ******************************* **..:****** ***.* .:** :********:: *:***.*** :*:*******************************:********:******:***:***************: * * ****:.******:**************: :***: :::********:************************.:****::.****************:** .*********************************************************:**.*******************************:********************************************* .*.*************:*****************************************:*********************************************:*********************:*****.***:", "identical_positions": 571, "similar_positions": 64, "identity": "86.91%" }, { "cls_id": "homologset.agr.RGD:620781", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V8P1-1", "uniprot_id": "Q4V8P1_RAT", "id": "Q4V8P1-1", "name": "", "aln": "MPTMSRPALDVKGGTTSGKEDANQEMNSLAYSNLGVKDRKAVTVLHYPGVTANGAKANGVPTSPSGSSSPTGSPTATPSTKPPSFNLHPTPHLLASMQLQKLNSQYQGAAATAAAALAAPSQPGEDEPLLNWGTG-IQAGAGGSPGSVSP-AGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99966-1", "uniprot_id": "CITE1_HUMAN", "id": "Q99966-1", "name": "Cbp/p300-interacting transactivator 1", "aln": "MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSG--SPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAA------ATPGQPGEAGPLQNWDFG-AQAGG---AESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97769-1", "uniprot_id": "CITE1_MOUSE", "id": "P97769-1", "name": "Cbp/p300-interacting transactivator 1", "aln": "MPTMSRPALDVKGGTTSGKEDANQEMNSLAYSNLGVKDRKAVTVLHYPGVTANGAKANGVPTSSSGSTSPIGSPTATPSSKPPSFNLHPTPHLMASMQLQKLNSQYQGAAATAAAALTGAGLPGEEEPMQNWVTAPLVVGG--SPGSVSPPAGAQSPALIDSDPVDEEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1NHQ5-1", "uniprot_id": "A0A8M1NHQ5_DANRE", "id": "A0A8M1NHQ5-1", "name": "", "aln": "--------------------------MSLLCSSTTMKDRDSLSLLHYSG---SGKTSPQFPSASLHSSSPVLA-------KPQPFCLQSGPHLIASMQLQKLNSHYQNLTS------TATTGPG-----RGYTASMLSPGQ------ISSPGAAQASGIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQNEFDFIADVPAGC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *. :***.::::***.* .* .: *::. ** : ** .* *:. ***:***:******:**. :: : . ** .: . * :*. ..**:..:************************************** **.*:.*", "identical_positions": 79, "similar_positions": 41, "identity": "38.54%" }, { "cls_id": "homologset.agr.RGD:620782", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1AUH1-1", "uniprot_id": "PTPRU_MOUSE", "id": "B1AUH1-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "MARAQALVLALTFQFCAPETETPAAGCTFEEASDPVVPCEFSQAQYDDFQWEQVRIHPGTRTPEDLPHGAYLMVNASQHAPGQRAHIIFQTLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDHKGYIGLDDILLFSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAEHFFLQRQSGVLVPAAGVRHISHRRFLATFPLASVGRSEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVNLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLISRTKCAEPTRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYAVSLCYRYTLG---GSHNQTIRECVKMERGASRYTIKNLLPFRNIHVRLILTNPEGRKEGKEVTFQTDEDVPGGIAAESLTFTPLEDMIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLHPGTTYLFSVRARTSKGFGQAALTEITTNISAPSFDYADMPSPLGESENTITVLLRPAQGRGAPISVYQVVVEEERPRRLRREPGAQDCFSVPLTFETALARGLVHYFGAELAASSLLEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKAACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLGAIIVIIRKGRDRYAYSYYP-KPVNMTKATVNYRQEKTHMMSAVDRSFTDQSTLQEDERLGLSFMDAPGYSPRGDQRSGGVTEASSLLGGSPRRPCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFEGWDATKKKDKLKGGRQEPVSAYDRHHVKLHPMLADPDADYISAN---YID------GYHRSNHFIATQGPKPEMIYDFWRMVWQEQCASIVMITKLVEVGRVKCSRYWPEDSDMYGDIKITLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVNEFKATYREMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISSDGDPNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFVSGTANEDLVSRVFRVQNSSRLQEGHLLVRHFQFLRWSAYRDTPDSRKAFLHLLAEVDKWQAESGDGRTVVHCLNGGGRSGTFCACATVLEMIRCHSLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEALELR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAG7-1", "uniprot_id": "F1MAG7_RAT", "id": "F1MAG7-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "MARAQALVLALTFQFCAPETETPAAGCTFEEASDPVVPCEFSQAQYDDFQWEQVRIHPGTRTPADLPHGAYLMVNASQHAPGQRAHIIFQTLSENDTHCVQFSYFLFSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDHKGYIGLDDILLFSHPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFFLQRQSGVLVPAAGVRHISHRRFLATFPLASVGRSEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVNLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLLSRTKCAEPTRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYAVSLCYHYTLG---GSHNQTIRECVKMERGASRYTIKNLLPFRNVHVRLILTNPEGRKEGKEVTFQTDEDVPGGIAAESLTFTPLEDMIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLQPGTTYLFSVRARTSKGFGQAALTEITTNISAPSFDYADMPSPLGESENTITVLLRPAQGRGAPISVYQVVVEEERPRRLRREPGGQDCFSVPLTFETALARGLVHYFGAELAASSLLEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKAACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLGAIIIIIRKGRDRYAYSYYP-KPVNMAKATVNYRQEKTHMMTAVDRSFTDQSTLQEDERLGLSFMDAPGYSPRGDQRSSGVTEASSLLGGSPRRPCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFEGWDATKKKDKLKSGRQEPVSAYDRHRVKLHPMLGDPDADYISAN---YIDIRINRQGYHRSNHFIATQGPKPEMIYDFWRMVWQEQCVSVVMISKLVEVGRVKCSRYWPEDSDMYGDIKITLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPVVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVNEFKATYREMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISSDGDPNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFVSGTANEDLVSRVFRVQNSSRLQEGHLLVRHFQFLRWSAYRDTPDSRKAFLHLLAEVDKWQAESGDGRTVVHCLNGGGRSGTFCACATVLEMIRCHSLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEALELR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92729-1", "uniprot_id": "PTPRU_HUMAN", "id": "Q92729-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "MARAQALVLALTFQLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDRRGYMGLDDILLLSYPCAKAPHFSRLGDVEVNAGQNASFQCMAAGRAAEAERFLLQRQSGALVPAAGVRHISHRRFLATFPLAAVSRAEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLISRTKCAEPMRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYTVSLCYHYTLG---SSHNQTIRECVKTEQGVSRYTIKNLLPYRNVHVRLVLTNPEGRKEGKEVTFQTDEDVPSGIAAESLTFTPLEDMIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLHPGTTYLFSVRARTGKGFGQAALTEITTNISAPSFDYADMPSPLGESENTITVLLRPAQGRGAPISVYQVIVEEERARRLRREPGGQDCFPVPLTFEAALARGLVHYFGAELAASSLPEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQAASHLKGETRLNCIRIARKAACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLGAIIVIIRKGRDHYAYSYYP-KPVNMTKATVNYRQEKTHMMSAVDRSFTDQSTLQEDERLGLSFMDTHGYSTRGDQRSGGVTEASSLLGGSPRRPCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFEGWDATKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINAN---YID------GYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSDTYGDIKIMLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLLVRHFQFLRWSAYRDTPDSKKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEGLESR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B3DK56-1", "uniprot_id": "PTPRU_DANRE", "id": "B3DK56-1", "name": "Receptor-type tyrosine-protein phosphatase U", "aln": "-MNTCAFLLILAVQIHADSVEGPTAGCTFDEDSDPSL-CEFSQGEEDDFDWQLFRAHASPHSTSDLLRGSYMMVNSSQHAAGQRAQLLLQTLSENDTHCVQFSYFLYSRDGHSPGALRVYVRVNGGPLGIPVWNVSGSRGRQWHQVELAVSTFWPNEYQILLEATVD--RKGYIAVDDILLLNYPCYKAPHFSRLGDVEVNAGQNATFQCVAAGRPSEAEKFLLERHNGEVSSGGSVKHLGRNRFAVSFQLEDVQKPEQDLYRCVTQSSRGSGVSNFAELIVKVPPSPIAPPQLLRAGSTYLIIQLNTNSILGDGPIIRREIEYRASLAPWSEILGVNMVTYKLWHLDPDTEYHISVLLTRPGEGGTGPPGPPLISRTKCAEPMRALRGLRASEIQSRQLTLQWEVPAFNLTRCHTYSVSLCYRYTTAGGGGGHNTTVRECLAVEHNTSRFTLRDLPPFHTIQIRLALANTEGKKEGKEVMFQTEEDIPGGIAPESLTFTPLEDMIFLKWEEPVEPNGLITQYEISYQSIESSDPGINVPGPRRTVSKLKNETYHMFSNLHPGTTYLISVRARTAKGFGQTALTEITTNISAPTFDYGDMPSPLSETENTITVLLRPAQGRGAPVSTYQVVVEEEAGRKVKRELGIQDCFPIPTSHGEAQARGAPHYYTAELPPSSLSEATPFTVGDNHTYNGYWNSPLDPRKNYLVYFQAMSNFRGETRINCIRIARKAACKDHQRALEVTQRSEEMGLILGVCAGGLVVLILLLGAIIIIIKKGRDYYSYSYYPRKPGNMNKTPITYRQEKSNMMGSMERSFTDQSTLQEDERMALSFMDTHTCSTRSDPRSS-MNESSSLLGGSPRRQCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFDGWDINKKKDKTKG-RHDTLMGYDRHRVKLHPLLGDPNSDYINAN---YID------GYHRSNHFIATQGPKQETVYDFWRMVWQENCFSIVMITKLVEVGRVKCCKYWPDESEMYGDIKITLLKTETLAEYTVRTFALERRGYSAKHEVCQFHFTSWPEHGVPYHATGLLAFIRRVKTSTPLDAGPVVVHCSVGAGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRINMIQTEEQYIFIHDAILEACLCGETAIPVNEFALAYKEMLRVDSQSNSSQLREEFQTLNSVTPHLDVEECSIALLPRNREKNRSMDVLPPDRALAFLVTTEGESNNYINAALMDSFHRPAAFIVTPHPLPGTTSDFWRLVFDYGCTSVVMLNQLNQSNSAWPCVQYWPEPGLQQYGPMQVEFLSMSADEDIITRLFRVKNVTRLQEGQLVVCQFQFLRWSAYRDVPDSKKAFLNLLASVQKWQRECGEGRTVVHCLNGGGRSGTYCASNILMEMIQYQNIVDVFYAVKTLRNAKPNMVETLEQYRFCYELVLEYLDCLEVR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40048-1", "uniprot_id": "PTP3_YEAST", "id": "P40048-1", "name": "Tyrosine-protein phosphatase 3", "aln": "-------------------------------------------------------MKDSVDCPSILPTDRTSVLSETSTLVGSSSHVYSRHAPMNSYHNSMNSNIYHSPKASSP-------------------------------------------------------LVSYKTSSPVLLKRATAPVLPSFKPKEQRYNKPQGCSLITAVELG------------KIIETLPDEKVLLLDVR----PFTEHAKSIITNSIHVCLPSTLLRRKNFTFSKLLDNLTPSEQSVLKSKLAIDNLRIIIYDSTANQTESSVS----------------LPCYGIASKLIEFDTNVKKTVSILMCG-------FPQFKILFPDHINTNTFNSDCISSAEPKSP----------------------------------------KTNLMNSLHNTAPHMTATTPLSSPQMNLKLKVPDDSRSD-----------------------------HSNFSSSPSPRNVLSDSPMSSSSPISALFKFQLPAPQTNIN---------------------------------------------QMFKFSQNEEIMG---------------LETYLSAVNIKEEHERWYNNDSAKKSLQNFQFPKNQNSLEKDTNKDKLGFQIRYENLSKNYEKEVIDSVIPEWFQHLMSIPKIELVSQFQKLDFLE-----------------KRRLNHSVSFRKKENSFILEKPSS------------------------YP---------------EQLTSTSSSTIMPPKFPDVNKVQKRSHSQPIFTQYSKYKSMLSLESDSDSESDDVIISSGVELGAKNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYIN-----------------------ANYLSLPRFSVEQNSSFQTTTTTT------------RRVRYIATQAPMPSTVHDFYTCILNNGVPLVLSLTNDFENGIEKCYRYWQEGN--YNGIHVKLLEKKILKMPSTTSMRKNTMG----------------TQNSSLYSAGVQGNSSNYSTDNDNDN----------DNNNNNNNNSNIAVTAAACDDDDDDDDDAILIRKILLTYHDQEKPYELLQIQVKNWPDLGTLLNPISILQAINVKNHIIDTLFARN--------------YYQNDQLPTILVHCSAGCGRTGTLCTIDSILSNFEMFEMLQKEFVKLKYPAKLFDPISWTINIFRKQ----------------RISMVQNINQFIFIYDCLLFYFR--------------------------LRLDDITERTDG-------------------------------------------------DGSNK-----------DNISLSALIEQIEKLEILQTFVDDKLKELPQ------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * . ::. :. *. ::: : . *. * * : .* .. ** .* . :** .. * *. : :. : : .: * : . * :. . .* :.:: *:..: .*::*: : .*: : : * . ** ::.: :..: : ** .:*.:.: :*:*: * :: : : :* :: : : . : : * . ::.* * .:. :.. . ::... .*..:::: :* .* *: .::*.*: .:. *.:.: . :. : :*. :: *.* . : * .* . . :: ..* : * *. . : : *: : ** . :. . : .*: *.:* .:** :. *. : .: : .*.* ..:*: .: * : .. . .*. .*:..:: .* . .:: *. * : . ** : :* :.. . :.::: : :.* : : ::.: .:. * ::****.* . ::**: : :: :: ::: .* * ** :** : . *..*:: *::.: * . :: : * :. . :::*: . . .:.. * .... :: : * *:. * : . : . :. : *: * ::: : : * *:. : : :*. . : :: . *: . .*: : . * *. : : ::::: . . :: :. . : *::::** : *: :: . :*:.: :. :* :*..: : * ::: : : *:. : :: : * ", "identical_positions": 113, "similar_positions": 350, "identity": "7.75%" }, { "cls_id": "homologset.agr.RGD:620783", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99P77-1", "uniprot_id": "GTPB4_RAT", "id": "Q99P77-1", "name": "GTP-binding protein 4", "aln": "MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQILSDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTIIKRQRQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFTTKSLFVGHVDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAVLYVMDLSEQCGHGLKEQLGLFQNIRPLFINKPLIVVASKCEVKRIAELSEEDQKIFLDLQAE-GFPVIETSTLTEEGVIQVKTEACDRLLAHRVETKMKGN-KVNEVLNRLHLAVPNKRDDKERPPFIPEGVVARRKR-MEIAEPKKKRERDLELEMGDD--YILDLQKYWDLMNSSEKYDKIPEIWEGHNAADYIDPAIMKKLEELEKGKKSSEQLLGSMPVSLRV------KTRKWWKIRQLAKQIR-EKK-KLKILQSKEKNTQGPRMPRTAKKVQR----ADLENEMRSLGVDMDDKDNAHY---AVRARRSRSVTRKRKREES----VPPSSIARSRSRSCSKTP-RDVSGLRDVKMVKKAKTMMK-KAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKERR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99ME9-1", "uniprot_id": "GTPB4_MOUSE", "id": "Q99ME9-1", "name": "GTP-binding protein 4", "aln": "MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQILSDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTIIKRQRQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFTTKSLFVGHMDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAVLYVMDLSEQCGHGLKEQLELFQNIRPLFINKPLIVVANKCDVKRIAELSEEDQKIFLDLQAE-GFPVIETSTLTEEGVIQVKTEACDRLLAHRVETKMKGN-KVNEVLNRLHLAVPNKRDDKERPPFIPEGVIARRKR-MEIEEPKKKRERDLELEMGDD--YILDLQKYWDLMNSSEKYDKIPEIWEGHNVADYIDPAIMKKLEELEK-EEELRTAAGEYDSDSES------EDEEMMEIRQLAKQIR-EKK-KLKILQSKEKNKQGPRMPRTAKKVQR----ADLENEMRSLGVDMDDKNNAHY---AVQARRSRSVTRKRKREES----VPPSSTARSRS--CSRTP-RDVSGLRDVKMVKKAKTMMK-KAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKDRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZE4-1", "uniprot_id": "GTPB4_HUMAN", "id": "Q9BZE4-1", "name": "GTP-binding protein 4", "aln": "MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQILTDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTVIKRQKQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFTTKSLFVGHMDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAVLYVMDLSEQCGHGLREQLELFQNIRPLFINKPLIVVANKCDVKRIAELSEDDQKIFTDLQSE-GFPVIETSTLTEEGVIKVKTEACDRLLAHRVETKMKGN-KVNEVLNRLHLAIPTRRDDKERPPFIPEGVVARRKR-METEESRKKRERDLELEMGDD--YILDLQKYWDLMNLSEKHDKIPEIWEGHNIADYIDPAIMKKLEELEK-EEELRTAAGEYDSVSES------EDEEMLEIRQLAKQIR-EKK-KLKILESKEKNTQGPRMPRTAKKVQR----TVLEKEMRSLGVDMDDKDDAHY---AVQARRSRSITRKRKREDS----APPSSVARSGS--CSRTP-RDVSGLRDVKMVKKAKTMMK-NAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKDRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V411-1", "uniprot_id": "NOG1_DROME", "id": "Q9V411-1", "name": "Nucleolar GTP-binding protein 1", "aln": "MSLYNFKKIMVVPPAKDFIDIMLSKTQRKTPTVVHKGYKISRIRAFYTRKVKYTQQNFHDRLSQIIQDFPKLDDVHPFYADLMNVLYDKDHYKLALGQLNTARHLVDNVAKDYVRLLKYGDSLYRCKQLKKAALGRMATIMKRQASNLTYLEQVRQHLSRLPTIDPYSRTIIICGFPNVGKSSFINKITRADVEVQPYAFTTKSLYVGHTDYKYLRWQVIDTPGILDHPLEERNVIEMQAITALAHLRACVLYFMDISEQCGHSLEEQVKLFESIKPLFTNKPLILAINKIDILTPEDLPEERRAIITKLQEDKNIPVMLMSTVQETGVMEVKTEACERLLSYRVDQKMRTK-KVDNILNRLHVAMPAPRDDKLRAPCIPEKASARLLQNADKAERKRKLEKEIEEEMGDD--YTLDLKKNYSEIPEEERYDIIPEFWQGHNIADYIDADIFDKLEELER-EEGLREESGVYKVPDMT------MDETLKEIREIAKQIR-GKRFELRDEKRLSSRKNKPVIPRNKQPKVRDRSVQKLVSTMEGLGVDMSGSENANFTKSVVDLRRGQVAVGSKKVPMQPLLDKESSAVVRKTGQPLKRAPSRDTLGIKNLAIRKKAQIMAKRDIAKKVTSRGLKGEADRFIGTKMPKHLFSGKRGNGKTDRR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02892-1", "uniprot_id": "NOG1_YEAST", "id": "Q02892-1", "name": "Nucleolar GTP-binding protein 1", "aln": "-MQLSWKDIPTVAPANDLLDIVLNRTQRKTPTVIRPGFKITRIRAFYMRKVKYTGEGFVEKFEDILKGFPNINDVHPFHRDLMDTLYEKNHYKISLAAISRAKSLVEQVARDYVRLLKFGQSLFQCKQLKRAALGRMATIVKKLRDPLAYLEQVRQHIGRLPSIDPNTRTLLICGYPNVGKSSFLRCITKSDVDVQPYAFTTKSLYVGHFDYKYLRFQAIDTPGILDRPTEEMNNIEMQSIYAIAHLRSCVLYFMDLSEQCGFTIEAQVKLFHSIKPLFANKSVMVVINKTDIIRPEDLDEERAQLLESVKEVPGVEIMTSSCQLEENVMEVRNKACEKLLASRIENKLKSQSRINNVLNKIHVAQPQARDDVKRTPFIPESVKN-LKKYDPEDPNRRKLARDIEAENGGAGVFNVNLKDKYLLEDDEWKNDIMPEILDGKNVYDFLDPEIAAKLQALEEEEEKLENE-GFYNSDDEEEIYDGFEASEVDDIKEKAAWIRNRQKTMIAEARNRKSLKNKAIMPRSKLTKSFG----KMEEHMSTLGHDMSALQDKQN----RAARKNRYVERGSDVVFG----DQDALTASTENGVKLRQTDRLLDGVADGSMRSKADRMAK-MERRERNRHAKQGESDRHNAVSLSKHLFSGKRGVGKTDFR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*.* .*..*:*::*: *.:********:: ::* *** ** ****:* :.: :::.:*: .**:::*:***: ***: **:*:***::*. :. *: **::**:*****:*:*:**::*****:******.*::*: . * ********:.***:*** :**:::**:********:. :*::**:***********:*** ******:*.:*******:* *: * ****:* *:****:.***.**:*****. :. *: **..*:*** **.:::. .* :: :* *: :: .:: .. :: * * .*::*:.:**::**: *:: *:: : :::::**::*:* * *** *.* *** . : ::* :::* * *. : ::*:. : . : * :**: :*:* *::*. * **: **. :: . * .*:: * ** :: : . .. .: . :**. : . * ** **. :: : *:.: . : . . . : . * *: : : .**. * * :: . . :**:**. .***:**** **.: *", "identical_positions": 236, "similar_positions": 204, "identity": "35.6%" }, { "cls_id": "homologset.agr.RGD:620784", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESE2-1", "uniprot_id": "TNF11_RAT", "id": "Q9ESE2-1", "name": "Tumor necrosis factor ligand superfamily member 11", "aln": "MRRANRDYGKYLRGSEEMGSCPGVPHEGPLHPAPSAPAPAPPPAASRFMFLALLGLGLGQVVCSIALFLYFRAQMDPNRISEDSTRCFYRILRLRENTGLQDSTLESEDTEALPDSCRRMKQAFQGAVQRELQHIVGPQRFSGVPAMMEGSWLDVARRGKPEAQPFAHLTINAADIPSGSHKVSLSSWYHDRGWAKISNMTLSNGKLRVNQDGFYYLYANICFRHHETSGSVPADYLQLMVYVVKTSIKIPSSHNLMKGGSTKNWSGNSEFHFYSINVGGFFKLRAGEEISVQVSNPSLLDPDQDATYFGAFKVQDID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35235-1", "uniprot_id": "TNF11_MOUSE", "id": "O35235-1", "name": "Tumor necrosis factor ligand superfamily member 11", "aln": "MRRASRDYGKYLRSSEEMGSGPGVPHEGPLHPAPSAPAPAPPPAASRSMFLALLGLGLGQVVCSIALFLYFRAQMDPNRISEDSTHCFYRILRLHENADLQDSTLESED--TLPDSCRRMKQAFQGAVQKELQHIVGPQRFSGAPAMMEGSWLDVAQRGKPEAQPFAHLTINAASIPSGSHKVTLSSWYHDRGWAKISNMTLSNGKLRVNQDGFYYLYANICFRHHETSGSVPTDYLQLMVYVVKTSIKIPSSHNLMKGGSTKNWSGNSEFHFYSINVGGFFKLRAGEEISIQVSNPSLLDPDQDATYFGAFKVQDID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14788-1", "uniprot_id": "TNF11_HUMAN", "id": "O14788-1", "name": "Tumor necrosis factor ligand superfamily member 11", "aln": "MRRASRDYTKYLRGSEEMGGGPGAPHEGPLH-APPPPAPHQPPAASRSMFVALLGLGLGQVVCSVALFFYFRAQMDPNRISEDGTHCIYRILRLHENADFQDTTLESQDTKLIPDSCRRIKQAFQGAVQKELQHIVGSQHIRAEKAMVDGSWLDLAKRSKLEAQPFAHLTINATDIPSGSHKVSLSSWYHDRGWAKISNMTFSNGKLIVNQDGFYYLYANICFRHHETSGDLATEYLQLMVYVTKTSIKIPSSHTLMKGGSTKYWSGNSEFHFYSINVGGFFKLRSGEEISIEVSNPSLLDPDQDATYFGAFKVRDID", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.*** ****.*****. **.******* **..*** ****** **:*************:***:**************.*:*:******:**:.:**:****:* :******:*********:*******.*:: . **::*****:*:*.* ************:.********:*****************:***** **********************.:.::********.**********.******** *********************:*****::*********************:***", "identical_positions": 258, "similar_positions": 45, "identity": "81.13%" }, { "cls_id": "homologset.agr.RGD:620785", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99041-1", "uniprot_id": "TGM4_RAT", "id": "Q99041-1", "name": "Protein-glutamine gamma-glutamyltransferase 4", "aln": "-----------------------------------------------MDSRNMLVVYSVNLEKKLNAAAHHTIEY----QTQKLVLRRGQIFSLKVMLNRPLQSHDELKLIFNTGHN---MPFYTVELDPMTSYR-------SKGWQVKIAKQSGVEVVLNVISAADAVVGRYTMNVN------EFDAG----VFFLLFNPWCSDDSVFMASEEDRAEYVLNDTGYMYMGFAKQIKEKPWTFGQFEKYILNCCFRLLTH---LEPKEMQSPVLVSRAICTMMCAANNFGVLVGNWTGDYSNGTAPYVWASSVPILQQHYITRMPVRFGQCWVFSGVLTTALRAVGIPARSVTNFESAHDTEKNLRVDIYLDESGKTIPHLTKDSVWNFHMWTDAWMKRQDLPQG----HDGWQVLDSTPQEISEGQFRIGPSPVSAIRQGLVQIMYDTTFVFTEVNGDKYIWLVKQNQEREKNVLIAVETASIGKNISTKMVGENRRQDITLHYKFPEGSPEERKAMEKAS--GKRPDDKLNSRTLH-----ISVLQNSVELGHPINLTIVLKRKTATPQNVN-ISCSLDLQTYTGNKKTNLGVIQKTVQIQGQESEVSLSMDSSFYIYKLGMVDDEMVIKGFIIAEIVDSGERVATDTTLCFLYSAFSVEMPSTSKVN-QPLTITCNFKNTLPIPLTNIKFSVESLGLNNMKSWEQETVPPGKTINFQIECTPVKTGPRKFIVKFISRQVKEVHAEKVVLITK--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZH1-1", "uniprot_id": "TGM4_MOUSE", "id": "Q8BZH1-1", "name": "Protein-glutamine gamma-glutamyltransferase 4", "aln": "-----------------------------------------------MDSRNVLIIYAVNVERKLNAAAHHTSEY----QTKKLVLRRGQIFTLKVILNRPLQPQDELKVTFTSGQR---DPPYMVELDPVTSYR-------SKGWQVKIAKQSGVEVILNVISAADAVVGRYKMRVN------EYKAG----VFYLLFNPWCSDDSVFMASEEERAEYILNDTGYMYMGFAKQIKEKPWTFGQFEKHILSCCFNLLFQ---LENNEMQNPVLVSRAICTMMCAAN-GGVLMGNWTGDYADGTAPYVWTSSVPILQQHYVTRMPVRYGQCWVFSGILTTALRAVGIPARSVTNFESAHDTEKNLTVDIYLDESGKTIPHLTKDSVWNFHVWTDAWMKRQDLPHG----YDGWQVLDSTPQEISDGGFRTGPSPLTAIRQGLIQMKYDTTFVFTEVNGDKFIWLVKQNQEREKNILIAVETASLGKKISTKMVGENRREDITLQYRFPEGSPEERKVMAKAS--GKPSDDKLNSRTLNN-SLQISVLQNSLELGAPIYLTITLKRKTATPQNVN-ISCSLNLQTYTGNKKTNLGVIQKTVQIHGQESRVFLTMDASYYIYKLGMVDDEMVIGGFIIAEIVDSGERVATDTTLCFLYSAFSVEMPSTGKVK-QPLVITSKFTNTLPIPLTNIKFSVESLGLANMKSWEQETVPPGKTITFQMECTPVKAGPQKFIVKFISRQVKEVHAEKVVLISK--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49221-1", "uniprot_id": "TGM4_HUMAN", "id": "P49221-1", "name": "Protein-glutamine gamma-glutamyltransferase 4", "aln": "----------------------------------------------MMDASKELQVLHIDFLNQDNAVSHHTWEF----QTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFSTGPNPSIAKHTLVVLDPRTPSD-------HYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKTGNHILKSEEN----ILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFEKNVLDCCISLLTES-SLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGGTAPYKWTGSAPILQQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKG----YDGWQAVDATPQERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAF--LLLSSEREHRRPVKENFLHMSVQSDDVLLGNSVNFTVILKRKTAALQNVN-ILGSFELQLYTGKKMAKLCDLNKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIG-QLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLITK--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLU2-1", "uniprot_id": "Q9VLU2_DROME", "id": "Q9VLU2-1", "name": "protein-glutamine gamma-glutamyltransferase", "aln": "MGQKLSCCQKCGDWKWCTSKDNEESTLRIRNANANYFTGIPQGDKTDGASSAVLGVLKVDLCLEDNHEEHHTSHFYAAAAKEALVVRRGEPFRLKIHFNRDYSPSKDAISFIFTVADDTKPSPGHGTLNALVPHDGIDYLGDTLEWGAGIESHEGQTLTVLIKPPSTCPVTEWKLDIDTKLLGDGSRSYPLPLPIYVLFNPWCPDDQVYLEDRDQRKEYVMHDTTLIWRGSYNRLRPSVWKIGQFERHVLECSLKVLGTVGRIPPAYRGDPVRVARALSALVNSVDDDGVLLGNWSEDFSGGVAPTKWTGSVEILQQFYKTQKSVKFAQCWNFSGVLTTIARSLGIPSRIITCYSSAHDTQASLTVDVFIDANNKKLDAETTDSIWNYHVWNELWMQRPDLGVGEHGTFDGWQVVDATPQEASDNMYRVGPASVAAVKNGDILRPFDGGFVFAEVNADKLYWRYN--GPSQPLKLLRKDTLAIGHLISTKAVLKWEREDITDTYKHAERSEEERSTMLKALKQSRHAFSRYYLNDNFNDIEFDMELKDDIKIGQSFSVVLKVSNKSESRTHMATGQISCDAVLYTGVGAVEVKTLGFELELEPKSS--DYVRMEVIFEEYYDKLSSQAAFQISAAAKVKDTDYDYYAQDDFRVRKPDIKFQLGEAAIVAQKELDVILRLENPLPIPLHKGVFTVEGPGIEQPLKFKIAEIPVGGTAAATFKYTPPYAGRGTMLAKFTSKELDDVDGYRHYEIEPRPEDLLQPNGSHRSSNIIRRRTDVIA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : ::. : * *** .: .. *.***: * *:: :*: .. .: : : *:. .. * . : ...* : : : ... . : .: : :. :::****** :* *:: ..::* **:::** : * . :: . *.:****: :*.*.: :* : .** *.**:.::: . ***:***: *: .*.** *:.*. ****.* *: .* :.*** *:*:*** *::***:* :* :.*****: .* ** ::: ..:.: * **:**:*:*.: **:* ** * .****.:*:**** *:. : **:.::*:::* : :* ***:***.*: * : : :: :* ::*: **** * : .*.*** *:..* * ***..* :* . .: . .:.: :* .. ..: :..*: : :: * : *** .:: : ::. : * : :..: .: *:: :: :: . . :..:: .:. : : * : *.*.*** . *::*. *: . . . : * * :: ** :* .::.*: *:::.::.. : * ", "identical_positions": 163, "similar_positions": 236, "identity": "20.9%" }, { "cls_id": "homologset.agr.RGD:620786", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54275-1", "uniprot_id": "MSH2_RAT", "id": "P54275-1", "name": "DNA mismatch repair protein Msh2", "aln": "MAVQPKE-----TLQLEGAAEVGFVRFFEGMPEKPSTTVGLFDRGDFYTAHG-EDALLAAREVFKTQGVIK--YMGPAGAK----TLQTVVLSKMNFESFVKDLLLVRHYRVEVYKNKAGNKASKENDWYLAYKASPGNLSQFEDILFGNNDMATSIGIMGIKLSTVDG-QRQVGVGDVDSTQRKLGLCEFPDNDQFSNLEALLIQIGPKECILPGGETAG----DMGKLRQVIQRGGILITERKRIDFSTKDIYQDLNRLLKGRKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELATFDFSQYMKLDMAAVRALNLFQGSVEDTTGS-----------------QSLAAFLNKCKTAQGQRLVSQWIKQPLMDKNRIEERLNLVEAFVEDSELRRALQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGVKQLPNVIQALEKYQGRH------QALLLAVFVTPLTDLRSDFSKFQEKIETTLDMDQVE-NHEFLVKPSFDPNLSELREVMDGLEKKMQSTLISAARGLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSELSSLNEEYTKNKGEYEEAQDAIVKEIVNISSGYVEPMQTVNDVLAHLDAVVSFAHVSNAAPVPYVRPVILEK-GKGRIIVKASRHACVEVQHDVAFIPNDVHFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATNIGAFCMFATHFHELTALASQIPTVNNLHVTALTT---------EETLTMLYQVKTGVCDQSFGIHVAELANFPRHVIECAKQKALELEEFQSIGTSQGHDET--QPAAKRRCLEREQGEKIILEFLSKVKQVP---FTDLSEESVSVKLKQLKAEVLAKNNSFVNEIISRVKAP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43247-1", "uniprot_id": "MSH2_MOUSE", "id": "P43247-1", "name": "DNA mismatch repair protein Msh2", "aln": "MAVQPKE-----TLQLEGAAEAGFVRFFEGMPEKPSTTVRLFDRGDFYTAHG-EDALLAAREVFKTQGVIK--YMGPAGSK----TLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNKAGNKASKENEWYLAFKASPGNLSQFEDILFGNNDMSASVGVMGIKMAVVDG-QRHVGVGYVDSTQRKLGLCEFPENDQFSNLEALLIQIGPKECVLPGGETTG----DMGKLRQVIQRGGILITERKRADFSTKDIYQDLNRLLKGKKGEQINSAALPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELATFDFSQYMKLDMAAVRALNLFQGSVEDTTGS-----------------QSLAALLNKCKTAQGQRLVNQWIKQPLMDRNRIEERLNLVEAFVEDSELRQSLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPSVIQALEKYEGRH------QALLLAVFVTPLIDLRSDFSKFQEMIETTLDMDQVE-NHEFLVKPSFDPNLSELREVMDGLEKKMQSTLINAARGLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSELSSLNEEYTKNKGEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAHLDAIVSFAHVSNAAPVPYVRPVILEK-GKGRIILKASRHACVEVQDEVAFIPNDVHFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISDYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTT---------EETLTMLYQVKKGVCDQSFGIHVAELANFPRHVIACAKQKALELEEFQNIGTSLGCDEA--EPAAKRRCLEREQGEKIILEFLSKVKQVP---FTAMSEESISAKLKQLKAEVVAKNNSFVNEIISRIKAPAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43246-1", "uniprot_id": "MSH2_HUMAN", "id": "P43246-1", "name": "DNA mismatch repair protein Msh2", "aln": "MAVQPKE-----TLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHG-EDALLAAREVFKTQGVIK--YMGPAGAK----NLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLAYKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDG-QRQVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETAG----DMGKLRQIIQRGGILITERKKADFSTKDIYQDLNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMKLDIAAVRALNLFQGSVEDTTGS-----------------QSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKH------QKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVE-NHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEK-GQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTT---------EETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQYIGESQGYDIM--EPAAKKCYLEREQGEKIIQEFLSKVKQMP---FTEMSEENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43248-1", "uniprot_id": "MSH2_DROME", "id": "P43248-1", "name": "DNA mismatch repair protein spellchecker 1", "aln": "MQAKATDSRQEPTLNMDTNARRNFIKFHAKLGEKPATTVRFFDHTDRYTVHGSDDCELVAKIVYKSTAFIG--ALLPDDKKE---TLQFVSMSKGNFELAVRELLLVRNYRVEVYVKNS-------SDWEIEYRGSPGNLLQFEDILFSNKEVLVGNSIISLLVKLDGGGQRRVGVASVEQNDCKFQLLEFLDDDFFTELEATVVLLGPKECLLP--SIEG----EYSAVKTLLDRNGVMITMPKKS--GDNDLLQDLNRLLRFAKGQQEDATGLKELQLQLASNALKTAIKYLDLVNDAGNLGHYEIKQLDLNRFVHLDSAAVAALNIMPKPGTHPSMPS-------------YRWQSVLGVLDHCRTPQGHRLMGQWVKQPLRSRNILNDRHNIVQCLLESPDTMETLSLDYLKRIPDILMLTKKLMRRKANLQDLFRIYQVILRTPKILKVLHELDN---------STIESVICAPFKSFLKDLTGLKQMVEQVVDFEAIE-RGEYLVKASFDSRLMELQQMMTELYSKMEELQFKCSQELNLDGKNQVKLESVAKLGHHFRITVKDDSVLRKNKNYRIVDVIKGGVRFTSDKLEGYADEFASCRTRYEEQQLSIVEEIIHVAVGYAAPLTLLNNELAQLDCLVSFAIAARSAPTPYVRPKMLEE-GARELVLEDVRHPCLELQEHVNFIANSVDFKKEECNMFIITGPNMGGKSTYIRSVGTAVLMAHIGAFVPCSLATISMVDSILGRVGASDNIIKGLSTFMVEMIETSGIIRTATDKSLVIIDELGRGTSTYEGCGIAWSIAEHLAKETKCFTLFATHFHEITKLAETLSTVKNCHMAAVAD---------ADDFTLLYQVRSGVMEKSFGIQVARLANFPEHVVQNAQEVYNEFED---------------EHVDKQKKEDKALLEKIQVAIQQLSTAGN---NVDINVEDLTQLVTQFTKDIEQLDSDYFKSVLATSEA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25847-1", "uniprot_id": "MSH2_YEAST", "id": "P25847-1", "name": "DNA mismatch repair protein MSH2", "aln": "MSSTRPE-----LKFSDVSEERNFYKKYTGLPKKPLKTIRLVDKGDYYTVIG-SDAIFVADSVYHTQSVLKNCQLDPVTAKNFHEPTKYVTVSLQVLATLLKLCLLDLGYKVEIY----------DKGWKLIKSASPGNIEQVNELMNMNIDSSIIIASLKVQWNSQDG-NCIIGVAFIDTTAYKVGMLDIVDNEVYSNLESFLIQLGVKECLVQDLTSNSNSNAEMQKVINVIDRCGCVVTLLKNSEFSEKDVELDLTKLLG-----DDLALSLPQKYSKLSMGACNALIGYLQLLSEQDQVGKYELVEHKLKEFMKLDASAIKALNLFPQGPQNPFGSNNLAVSGFTSAGNSGKVTSLFQLLNHCKTNAGVRLLNEWLKQPLTNIDEINKRHDLVDYLIDQIELRQMLTSEYLPMIPDIRRLTKKLN-KRGNLEDVLKIYQFSKRIPEIVQVFTSFLEDDSPTEPVNELVRSVWLAPLSHHVEPLSKFEEMVETTVDLDAYEENNEFMIKVEFNEELGKIRSKLDTLRDEIHSIHLDSAEDLGFDPDKKLKLENHHLHGWCMRLTRNDAKELRKHKKYIELSTVKAGIFFSTKQLKSIANETNILQKEYDKQQSALVREIINITLTYTPVFEKLSLVLAHLDVIASFAHTSSYAPIPYIRPKLHPMDSERRTHLISSRHPVLEMQDDISFISNDVTLESGKGDFLIITGPNMGGKSTYIRQVGVISLMAQIGCFVPCEEAEIAIVDAILCRVGAGDSQLKGVSTFMVEILETASILKNASKNSLIIVDELGRGTSTYDGFGLAWAIAEHIASKIGCFALFATHFHELTELSEKLPNVKNMHVVAHIEKNLKEQKHDDEDITLLYKVEPGISDQSFGIHVAEVVQFPEKIVKMAKRKANELDDLKTNNEDLKKAKLSLQEVNEGNIRLKALLKEWIRKVKEEGLHDPSKITEEASQHKIQELLRAIANEPEKENDNYLKYIKALLL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : . .* : . : :** .*: :.*: * **. * .*. :.* *::: ..: : * * : * :* : :: ** *:**:* . * : .****: *.:::: * : . : : .* : :**. :: *. : :: ::: :::**: :: :* ***:: . : : :::* * ::* *. . :*: **.:** : : * : ::: .: .: * :*:*:.: .:.*::*: .:..:::** :*: ***:: .. . *: .*::*:* * **:.:*:**** . : ::.* ::*: :::. : . * : * :**: *:**: : .**:* ::** : *.:::.: . : :* :*: . :: ::: :* .:*:: * . *:::* .*: .* :::. : * .::.. :..:. *.:* :::**:. * :*:* :: . **::*:: :. * *: *:..:* . :* : .*:: * ::*.**:::: *. : :. **:** :.*** .: ** **:** : . . : **. :*:*..: **.*.* ::. : : ***************..*. ***:**.****. * :::**.** ****.*. :**:****.*::**:.*::.*:..**:*:**********:* *:**:*::::*.: .* :*******:* *:. :..*:* *:.* : :*:**:*. *: ::****:**.:.:**.::: *:. *::: : . : : :: . . . ..: : : : :..:.: : : ", "identical_positions": 234, "similar_positions": 349, "identity": "23.61%" }, { "cls_id": "homologset.agr.RGD:620788", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31646-1", "uniprot_id": "S6A13_RAT", "id": "P31646-1", "name": "Sodium- and chloride-dependent GABA transporter 2", "aln": "-MDNRVSGTTSNGETKPVCPVMEKVEEDGTLEREQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRKICPIFEGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKTNNSLNVTS-ENATSPVIEFWERRVLKISDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCVALCILNSSTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREILILIVSVVSFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGASRFYDNIEDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSIYKLRTLKGPLRERLRQLVCPAEDLPQ--------------------KSQPELTSPATPMTSLLRLTELESNC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31649-1", "uniprot_id": "S6A13_MOUSE", "id": "P31649-1", "name": "Sodium- and chloride-dependent GABA transporter 2", "aln": "-MENRASGTTSNGETKPVCPAMEKVEEDGTLEREHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKANDSMNVTS-ENATSPVIEFWERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCILNSSTSFMAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREVLILIVSVISFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAGRFYDNIEDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMICIPAWSIYKLRTLKGPLRERLRQLVCPAEDLPQ--------------------KNQPEPTAPATPMTSLLRLTELESNC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSD5-1", "uniprot_id": "S6A13_HUMAN", "id": "Q9NSD5-1", "name": "Sodium- and chloride-dependent GABA transporter 2", "aln": "-MDSRVSGTTSNGETKPVYPVMEKKEEDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYLFSSFTIDLPWGGCYHEWNTEHCMEFQKTNGSLNGTS-ENATSPVIEFWERRVLKISDGIQHLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCFLNSGTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLILGVSVVSFLVGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLFLTPAVCTATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSLYRLGTLKGPFRERIRQLMCPAEDLPQ--------------------RNPAGPSAPATPRTSLLRLTELESHC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IWS9-1", "uniprot_id": "A0AC58IWS9_DANRE", "id": "A0AC58IWS9-1", "name": "Transporter", "aln": "MKAGQKEMEPSNGLNRPLEIVP--HAEVKMKDRGQWSNKLEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLEISLGQYTSEGGITCWRKISPLFEGIGYATQVIVALLNFYYIIVLAWGIFYLSNSFTWNLPWSSCNNTWNTESCMEFQRRNDSVDQSYLDNATSPVIEFWERRVLRISSGIEDIGTLHWDLVLCLLLAWVLCYFCIWKGVKSTGKVVYFTATFPYVMLVILLIRGVTLPGASRGIQFYLYPDLGRLADPQVWMDAGTQIFFSYAICLGCLTALGSYNKYNNNCYRDSLALCFLNSGTSFVAGFAIFSILGFMSYEQNVPISEVAESGPGLAFIAYPRAVSMMPISPLWACFFFIMIVLLGLDSQFVCVESLVTAMVDMYPSFFRRKNRRELLILVVAIVSFLVGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFETVCIAWIYGANRFYDNIEDMIGYRPGPYIKYCWLFFTPATCFGTFAFSLIKYTPLKYNNEYVYPWWGYALGWMLALSSMICVPLWVIYRMGTTKGSLMERVQFLIRPSPDLPKSRREQEKLQAVFSADGDSLHQHSTHTHSHTHNRDGYFPVREKESHC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . .*** .:*: . * :* :*.**:************************************:**********:** :*****.:**:*.**:*.*:*******:*:** ***.***:****.:*** .*** :***..* : **** *:***: *.*:: : :***************::*.**:.:*:*:*:*.*******::************************:***:***********::********:: ** ***************:****************:******.:***:***.***:************* **.********************** *:*:****** **:*:******************:***** .**:*****:*** *:::**::*********************************::*:**:*** ************:* * *******:***.* .** *********.**::*.***** ****:******:*:* * :*:: * **.: **:: *: *: ***: : . : : . : : * **:*", "identical_positions": 427, "similar_positions": 112, "identity": "68.43%" }, { "cls_id": "homologset.agr.RGD:620789", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q924S4-1", "uniprot_id": "KREM1_RAT", "id": "Q924S4-1", "name": "Kremen protein 1", "aln": "MAPPAARLALLSAAALTLAARPAPGPRPSPECFTANGADYRGTQSWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKHGEAASTECNNVCFGDHTQPCGGDGRIILFDTLVGACGGNYSSMAAVVYSPDFPDTYATGRVCYWTIRVPGASRIHFNFTIFDIRDSADMVELLDGYTHRVLVRFDGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQATKEEPPQERPAINQTLAEVITEQANLSVSAAHSSKVLYVITSSPSHPPQTVPGSHSWVPSVGASGHRVEGWTVYGLATLLILTVTAVVAKILLHVTFKSHRVTASGDLRDCRQPGTSGEIWTIFYEPSTTISIFKKKLKGQSQQDDRNPLVSD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N43-1", "uniprot_id": "KREM1_MOUSE", "id": "Q99N43-1", "name": "Kremen protein 1", "aln": "MAPPAARLALLSAAALTLAARPAPGPRSGPECFTANGADYRGTQSWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKHGEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMAAVVYSPDFPDTYATGRVCYWTIRVPGASRIHFNFTLFDIRDSADMVELLDGYTHRVLVRLSGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQATKEEPPQERPAVNQTLAEVITEQANLSVSAAHSSKVLYVITPSPSHPPQTAPGSHSWAPSVGANSHRVEGWTVYGLATLLILTVTAVVAKILLHVTFKSHRVPASGDLRDCRQPGASGDIWTIFYEPSTTISIFKKKLKGQSQQDDRNPLVSD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MU8-1", "uniprot_id": "KREM1_HUMAN", "id": "Q96MU8-1", "name": "Kremen protein 1", "aln": "MAPPAARLALLSAAALTLAARPAPSPGLGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPPQTVPGSNSWAPPMGAGSHRVEGWTVYGLATLLILTVTAIVAKILLHVTFKSHRVPASGDLRDCHQPGTSGEIWSIFYKPSTSISIFKKKLKGQSQQDDRNPLVSD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************.* .***************.************************************************************************************************************************************:*********.*******************************:*::***************************:***.*.:*********************.*: *************************************.*** ******:***:***************:*********.********.***:**.*.:**..*********************:***************.********:***:**:**:***:***:***********************", "identical_positions": 435, "similar_positions": 34, "identity": "91.97%" }, { "cls_id": "homologset.agr.RGD:62079", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35165-1", "uniprot_id": "GOSR2_RAT", "id": "O35165-1", "name": "Golgi SNAP receptor complex member 2", "aln": "MEPLYQQTHKQVHEIQSHMGRLETADKQSVHLVENEIQASIDQIFSHLERLEILS--SKEPPNRRQNAKLRVDQLKYDVQHLQTALRNFQHRRQAKEQQERQRDELLS---------RTFTTNDS--------------------DTTIPMDESLQFN-SSLQNIHHGMDDLIGGGHSILEGLRAQRLTLKGTQKKILDIANMLGLSNTVMRLIEKRAFQDKYFMIGGMLLTCAVMFLVVQYLT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35166-1", "uniprot_id": "GOSR2_MOUSE", "id": "O35166-1", "name": "Golgi SNAP receptor complex member 2", "aln": "MEPLYQQTNKQVQEIQSHMGRLERADKQSVHLVENEIQASIEQIFSHLERLEILS--SKEPLNRRQNAKLRVDQLKYDVQHLQTALRNFQHRRQVREQQERQRDELLS---------RTFTTNDS--------------------DTTIPMDESLQFN-SSLHNIHHGMDDLIGGGHSILEGLRAQRLTLKGTQKKILDIANMLGLSNTVMRLIEKRAFQDKYFMIGGMLLTCAVMFLVVQYLT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14653-1", "uniprot_id": "GOSR2_HUMAN", "id": "O14653-1", "name": "Golgi SNAP receptor complex member 2", "aln": "MDPLFQQTHKQVHEIQSCMGRLETADKQSVHIVENEIQASIDQIFSRLERLEILS--SKEPPNKRQNARLRVDQLKYDVQHLQTALRNFQHRRHAREQQERQREELLS---------RTFTTNDS--------------------DTTIPMDESLQFN-SSLQKVHNGMDDLILDGHNILDGLRTQRLTLKGTQKKILDIANMLGLSNTVMRLIEKRAFQDKYFMIGGMLLTCVVMFLVVQYLT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRL2-1", "uniprot_id": "GOSR2_DROME", "id": "Q9VRL2-1", "name": "Probable Golgi SNAP receptor complex member 2", "aln": "MESLYHQTNNVVKDIERDFQRLSQLSAQESLDVENGIQLKITQANANCDRLDVLL--YKVPPSQRQSSKLRVDQLKYDLRHLQTSLQTARERRQRRMQEISEREQLLN---------HRFTANSAQPE-----------------ETRLQLDYELQHH-TQLGNAHRGVDDMIASGSGILESLISQRMTLGGAHKRIQAIGSTLGLSNHTMKLIERRLVEDRRIFIGGVVVTLLIIALIIYFLVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25385-1", "uniprot_id": "BOS1_YEAST", "id": "P25385-1", "name": "Protein transport protein BOS1", "aln": "MNALYNHAVKQKNQLQQELARFEKNSVTAPISLQGSISATLVSLEKTVKQYAEHLNRYKEDTNAEEIDPKFANRLATLTQDLHDFTAKFKDLKQSYNENNSRTQLFGSGASHVMDSDNPFSTSETIMNKRNVGGASANGKEGSSNGGGLPLYQGLQKEQSVFERGNAQLDYILEMGQQSFENIVEQNKILSKVQDRMSNGLRTLGVSEQTITSINKRVFKDKLVFWIALILLIIGIYYVLKWLR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.*:::: : :::: : *:. . ::. *. .: . .: * . .: .::* :.*: . :. :: :: . : : . . *::..: : : ** . : : . : :* :: * ::.: *. * .:.:: **:*: .: *::* .:*: .: .::: : :: :* ", "identical_positions": 21, "similar_positions": 89, "identity": "8.57%" }, { "cls_id": "homologset.agr.RGD:620790", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y6X1-1", "uniprot_id": "SERP1_HUMAN", "id": "Q9Y6X1-1", "name": "Stress-associated endoplasmic reticulum protein 1", "aln": "-MVAKQRIRMANEKHSKNITQRGNVAKTSRNAPEEKASVG--PWLLALFIFVVCGSAIFQIIQSIRMGM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R2C1-1", "uniprot_id": "SERP1_RAT", "id": "Q9R2C1-1", "name": "Stress-associated endoplasmic reticulum protein 1", "aln": "-MVAKQRIRMANEKHSKNITQRGNVAKTSRNAPEEKASVG--PWLLALFIFVVCGSAIFQIIQSIRMGM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1W5-1", "uniprot_id": "SERP1_MOUSE", "id": "Q9Z1W5-1", "name": "Stress-associated endoplasmic reticulum protein 1", "aln": "-MVAKQRIRMANEKHSKNITQRGNVAKTSRNAPEEKASVG--PWLLALFIFVVCGSAIFQIIQSIRMGM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P38374-1", "uniprot_id": "YSY6_YEAST", "id": "P38374-1", "name": "Protein YSY6", "aln": "MAVQTPRQRLANAKFNKNNEKYRKYGKKKEGKTEKTAPVISKTWL-GILLFLLVGGGVLQLISYIL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * *:** *..** : : .*.... .*:.*.* .** .:::*:: *..::*:*. * ", "identical_positions": 19, "similar_positions": 28, "identity": "27.54%" }, { "cls_id": "homologset.agr.RGD:620791", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LNP8-1", "uniprot_id": "F1LNP8_RAT", "id": "F1LNP8-1", "name": "Nectin-1", "aln": "-----------------------------MARMGLAGAAGRWWGLALGLTAFFLPG----THTQVVQVNDSMYGFIGTDVILHCSFANPLPTVKITQVTWQKASNGSKQNMAIYNPTMGVSVLPPYEKRVEFLRP--------SFIDGTIRLSHLELEDEGMYICEFATFPTGNRESQLNLTVMAKPTN-WIEGTQAVLRARKGQDDKVLVATCTSANGKPPSVVSWETR----LKGEAEYQEIRNPNGTVTVISRYRLVP---SREAHRQSLACIVNYHLDR-----FRESLTLNVQYEPEVTIEGFDGNWYLQR-TDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFRG----PINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPTP-EHGRRAGQMPTAIIGGVAGSVLLVLIVVGGIIVALRRRRHTFKG-DYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPDDSDDEKKAGPLGGSSYEEEEEEE-GGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQYDPEQLDLAENMVSQNDGSFISKKEWYV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKF6-1", "uniprot_id": "NECT1_MOUSE", "id": "Q9JKF6-1", "name": "Nectin-1", "aln": "-----------------------------MARMGLAGAAGRWWGLALGLTAFFLPG----THTQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKASNGSKQNMAIYNPTMGVSVLPPYEKRVEFLRP--------SFIDGTIRLSGLELEDEGMYICEFATFPTGNRESQLNLTVMAKPTN-WIEGTRAVLRARKGQDDKVLVATCTSANGKPPSAVSWETR----LKGEAEYQEIRNPNGTVTVISRYRLVP---SREAHRQSLACIVNYHLDR-----FRESLTLNVQYEPEVTIEGFDGNWYLQR-TDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFRG----PITYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPTP-EHGRRAGQMPTAIIGGVAGSVLLVLIVVGGIIVALRRRRHTFKG-DYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPDDSDDEKKAGPLGGSSYEEEEEEE-GGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQYDPEQLDLAENMVSQNDGSFISKKEWYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15223-1", "uniprot_id": "NECT1_HUMAN", "id": "Q15223-1", "name": "Nectin-1", "aln": "-----------------------------MARMGLAGAAGRWWGLALGLTAFFLPG----VHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRP--------SFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTN-WIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETR----LKGEAEYQEIRNPNGTVTVISRYRLVP---SREAHQQSLACIVNYHMDR-----FKESLTLNVQYEPEVTIEGFDGNWYLQR-MDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKG----PINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVLIVVGGIVVALRRRRHTFKG-DYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPDDSDDEKKAGPLGGSSYEEEEEEEEGGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQYDPEQLDLAENMVSQNDGSFISKKEWYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B818-1", "uniprot_id": "NEC1A_DANRE", "id": "A0A8M2B818-1", "name": "Nectin 1a", "aln": "---------------------------------------MMFINLLLRLMCVFLIG----ADGQMVQMESSKAGFVGSQVELPCQFVNSNPPVKISQVTWQKLVNGTKQNVAIANPALGVSVLNPFRERVRFKNPAVRQRTP-SLEDTTIVFNRLKLTDESTYICEYTTFPAGNRENMVNLTVFARPMI-QMSLSTPSIVAGS-KDLKMTVATCVSANGKPASVITWETD----LDGESNTQEISNPDGTVTVRSDYFVVP---SREIHQQLLTCISTYNEEQ-----YTDSVTLNIQYEPEVIIEGFDGNWYLNR-ENVQLTCLADANPTISLYQWRYLNGTLPSSAELRDDVLIFKG----PVTYDIAGTYVCDATNSIGSGSASVEVIVTEFPSYPH---EVFQDQQQAGVVIGGAVVCGTVLLAAVTLLVVFLYRRRCMFKG-DYSTKKQILGNGYSKAGNVPSHPSLPHSLTFSDDSDEEKKLELYRGSSILGGSVQE-------------FHTCHDSRIKAYRTGLIEEHERCAFNEQTYIYEYGSE-VEVSVDMIPQMDGSVISKEEWYV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B0JYH6-1", "uniprot_id": "NEC1B_DANRE", "id": "B0JYH6-1", "name": "Nectin 1b", "aln": "MDKQESFFVGHKSHRCSQNRSVSQIHQRTSRLSECYTVPLQWPHGIVWHNNNSLLKGLEAGNGQSVQTDPSKSGFVGDTVELKCLFINGKPPVKISQVTWQKLINGTKQNVAIANPALGVSVLTPFKDRVSFKHPAVRQRTPSSLEDTTIVFSSLRLSDEAAYICEYTTFPAGNRENMVNLTVFARPVT-KMTLTSPTIVART-PKRKMPVATCMSANGKPPSVIKWDTT----LKGEATFQETRNPNGTVTVRSNYIVLP---SRETHRQKLTCIVTYRSER-----FTDSVILNVQYEPEVKIEGFDGNWYLNR-PNVQLTCNADANPPVTVYQWKLLNGSLPNNIEIKNNTLFFKG----PVTYELGGTYVCEATNSIGTRSGLVEVNVTELPNIPFDEREIPAELHSSGAAIGGAVGGVALLVAAIALLVFFLRRRQRTFKG-DYSTKKHVFGNGYSKAGGMPAHPPMPKNLQYPDDSDDEKKPAQISGPGGFESGDRD-------------FDGNSEDLKRPYFT--VDEGESRDYDERTLAFQYDPE-PEIADDMVSQTDGSVISKKEWYV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15278-1", "uniprot_id": "FAS3_DROME", "id": "P15278-1", "name": "Fasciclin-3", "aln": "-----------------------------MSRIVFICLAAILTDALTWAQVNVEPN--------TALLNE------GDRTELLCRYGRSINYCRIEIPGEQKVLNLSPEWSKTPGFTYFGAGLTAG--------------------QCGVSIERVKASNNGQVKCSLG-VEGEELSGTIDLVVALRPQQPIIELLSRPNREGYFNEGTEFRARCSVRDGRPPANISWYIDNMPANKRTTPLEVMSSTNDNVELSTSVQEIQWHLSPEDSNRKLVCRSHHQTDRESVPPQEAAYIINVRYAPVHQPDAAVYGLYLEHTAIVNITIRASPQPKIEWTIDGAIVGQGRTDGRYSAYEPQYLGNDEYNVTLAIAGLTLEDTTKIYNLRAS-NELGLTDYQVRISSSSKPPSSSLDVAAIVG-IVVAVAVLVLVVLLIVFARATGRWCFGGKSIKTPTNETSDTESADIKATSTATATTTMGGVGVSAEEEETVNEQESPQEQQQQQQKKAKRLPAFAAAILRRFNEKDSRKYKDNQESLNIVEGSVQEIPATNNAIDGNDNEPKAIVWQSTSPVWTFK---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . * * : . :* ** * : : . : : * . : : :. :. ::. *. . : .. ::*.* :* : . . * * :*:*.: :.* . : : ..:..* : : : * * .: *.* :. :: : :*::* * :. . **:: *::* *..:* : * .. . : * :. :.* : ::*: . :. *: :*: . . :* . ::: .: ::. : * * . .* .: .: * .. . .: . * :*:: . .: :. : * :. : : : . : . * : . : ", "identical_positions": 46, "similar_positions": 135, "identity": "7.97%" }, { "cls_id": "homologset.agr.RGD:620792", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54316-1", "uniprot_id": "LIPR1_RAT", "id": "P54316-1", "name": "Inactive pancreatic lipase-related protein 1", "aln": "----------MLTLWTVSLFLLGAAQ------------------------------------------GKEVCYDNLGCFSDAEPWAGTAIRPLKLLPWSPEKINTRFLLYTNENPTAFQTLQLSDP-----------------------------------LTIGASNFQVAR---------------------KTRFIIHGFIDKGE--ENWVVDMCKNMFQVEE---VNCICVDWKKGSQTT--YTQAANNVRVVGAQVAQMIDILVKNYSYSPSK-VHLIGHSLGAHVAGEAGSRTPG-----LGRITGLDPVEANFEGTP-EEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQMSGHLDFFPNGGQ-SMPGCKKNALSQIVDIDGIWSGTRD---FVACNHLRSYKYYLESILNPDGFAAYPCASYKDFESNKCFPCPDQG---------CPQMGHYADKFAGK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGDEPQKFFLNTGEAKNFARWRYR-----------------------VSLILSGRMVTGQVKVALFGSKGNTRQYDIFRG--------------------IIKPGATHSSEFDAK---LDVGTIEKVKFLWNNQVINPSFPKVGAAKITVQKGEERTEYN------------FCSEETVREDTLLTLLPCETSDTV------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5BKQ4-1", "uniprot_id": "LIPR1_MOUSE", "id": "Q5BKQ4-1", "name": "Inactive pancreatic lipase-related protein 1", "aln": "----------MLILWTIPLFLLGAAQ------------------------------------------GKEVCYDNLGCFSDAEPWAGTAIRPLKLLPWSPEKINTRFLLYTNENPTAFQTLQLSDP-----------------------------------STIEASNFQVAR---------------------KTRFIIHGFIDKGE--ENWVVDMCKNMFQVEE---VNCICVDWKRGSQTT--YTQAANNVRVVGAQVAQMIDILVRNFNYSASK-VHLIGHSLGAHVAGEAGSRTPG-----LGRITGLDPVEANFEGTP-EEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQMVGHFDFFPNGGQ-YMPGCKKNALSQIVDIDGIWSGTRD---FVACNHLRSYKYYLESILNPDGFAAYPCASYRDFESNKCFPCPDQG---------CPQMGHYADKFANN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSVEPQKFFLNTGEAKNFARWRYR-----------------------VSLTFSGRTVTGQVKVSLFGSNGNTRQCDIFRG--------------------IIKPGATHSNEFDAK---LDVGTIEKVKFLWNNHVVNPSFPKVGAAKITVQKGEERTEHN------------FCSEETVREDILLTLLPCKTSDTM------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54315-1", "uniprot_id": "LIPR1_HUMAN", "id": "P54315-1", "name": "Inactive pancreatic lipase-related protein 1", "aln": "----------MLIFWTITLFLLGAAK------------------------------------------GKEVCYEDLGCFSDTEPWGGTAIRPLKILPWSPEKIGTRFLLYTNENPNNFQILLLSDP-----------------------------------STIEASNFQMDR---------------------KTRFIIHGFIDKGD--ESWVTDMCKKLFEVEE---VNCICVDWKKGSQAT--YTQAANNVRVVGAQVAQMLDILLTEYSYPPSK-VHLIGHSLGAHVAGEAGSKTPG-----LSRITGLDPVEASFESTP-EEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMGHLDFFPNGGE-SMPGCKKNALSQIVDLDGIWAGTRD---FVACNHLRSYKYYLESILNPDGFAAYPCTSYKSFESDKCFPCPDQG---------CPQMGHYADKFAGR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSEEQQKFFLNTGEASNFARWRYG-----------------------VSITLSGRTATGQIKVALFGNKGNTHQYSIFRG--------------------ILKPGSTHSYEFDAK---LDVGTIEKVKFLWNNNVINPTLPKVGATKITVQKGEEKTVYN------------FCSEDTVREDTLLTLTPC------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VX01-1", "uniprot_id": "Q9VX01_DROME", "id": "Q9VX01-1", "name": "Lipase domain-containing protein", "aln": "MLSASYIILAMLMCHTVNAIAQEVARTVPTAPSPAHFAELSQAVHDQLMEHEERQRERVRRGHRSRRAVKRVCYGELGCFEDSGPFA-----YLEMLPSSPEEINTKFYFYSTRQRSDRPLMELSFLNMTNAFRGKRETEVSTSSPEGTSGRSSVASAPSSMSAVNATTFTTERPGGGQKKPTPSIDDLEGFDELSVRVIVHGFGSACP--HVWIYEMKTALMAVED---CIVICVDWENGATFPN-YVRAAANTRLVGKQLAMLLRNLQQHKGLDLMR-THVIGFSLGAHVSGFAGAELPG-----LSRITGLDPAGPLFEAQH-PKVRLDSSDAEFVDVIHSNGENLI-LGGLGSWQPMGHVDYYPNGGR-VQTGCSNLFVGAVTDFIWSAQAAEDEEGRSLCNHRRAYKFFIDSVAPRCLFPAFPCGNYDDFLKGRCFPCAQDDEDLAEGVPRCGNMGYYADRSTGRGQLYLLTREEEPFCAHQFQLQIFNSFNDLPLRTIGRLEAILEGDGGLNETFEISEKDDAEFFAGDIVSKIIVPHPALGFPTTLSLHYKSYSGWLSKGLPHWDIDKVVLTDSFGRSHSLCRPSTKLSSGSPVRLRLQAGNCELDNQEDYGAYTTQPPAAPPAQHAGNPTVAVPTDVPDSSVQESGLAASVDGVESAKQRKDIFNLGTSFKLARNQTYPLDQGDELPWQPILVGNSLDNETAEAAESSRSLSDSIAGEIFEPVLKDRRLAVNRGRNLQDYATTDSPEIMEPVLKATTPRVKQGKDLDLSESELAAGMVTTLGAITSAVAGSSRLPAKTMAQVGTGRSPDPDEPQTVQLLPFRLGELLQRAERYARETLLPLISVQAPRFFGFNVTPHDREPVRPGESRKPRYIPRYEESAFLNTSSNARRRSQKASRRSSAQQRNLLRLVRARSHGLDDGEDGSDEQREGEREQRNEVNYYTNVLQSESRSMRPEAPEYRPVFIDLPTYKPKTAAAFSTSAAVSAPLASAAVSGSVSLSRARRRGRSPKLIP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB91-1", "uniprot_id": "Q9VB91_DROME", "id": "Q9VB91-1", "name": "Lipase domain-containing protein", "aln": "--MRVFIALAALLATVSALPIEE--RVNGE------------------------------------NGWYVPQIDGSFEWMDKQDAEELLNRNSLIETRS---NDVSFYLYTKHNPTVGKEIRADAS------------------------------------SIEDSHFDKNQ---------------------GTRFVIHGWNGRYT--DGMNVKITRAWLSKGD---YNVIVVNWDRAQSVD--YISSVRAVPGAGAKVGEMIEYLHEHHHLSMES-LEVIGHSLGAHVAGYAGKQVGGK---RVHTIVGLDPAMPLFAYDK-PDKRLSTEDAFYVESIQTNG------GEKGFLKPIGKGTFYPNGGR-NQPGCGSDIGG-------------------TCAHGRSVTYYVEAVTE-DNFGTIKCHDYQAALANECG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STYSGVRMG----------------------------------AVTNAYMVDGDFYVPVNGQAPFGKIE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB90-1", "uniprot_id": "Q9VB90_DROME", "id": "Q9VB90-1", "name": "Lipase domain-containing protein", "aln": "--MKVFFVLAALLAAVSALPIEE--RVNGE------------------------------------NGWFIPKLDGSFEWMDMQDAEDLLANGAQMEGRIST-NAVNFYVYTKSNPTDGKEIKAKSG------------------------------------SVEDSHFNKDH---------------------GTRFVIHGWTQRYS--DDMNTRITKAWLSKGD---YNVIVVDWARARSVD--YASSVLAVPGAGGKVGEMIKYLHDHHGLDYDS-LEVIGHSLGAHVAGYAGKTVGDK---RVHTIVGLDPALPLFSYDK-PAKRLSTDDAHYVESIQTNG------GKLGFLKPIGKGAFYPNGGK-SQPGCGLDATG-------------------SCSHARSVLYYAEAVTE-DNFGSIKCHDYEDAVAKNCG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STYSSVRMG----------------------------------AITNAYMVEGDFYVPVNSEAPFGKIE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB89-1", "uniprot_id": "Q9VB89_DROME", "id": "Q9VB89-1", "name": "Lipase domain-containing protein", "aln": "--MKTFLILAFFALAASAIPIKESERVHGE------------------------------------NGWYVPQEDGTSEWVDMDVAEQWMEAQELLESRGLTTVPVKFYLYTSSNPTKGKKITASTK------------------------------------SIDASSFNSAH---------------------PTRFVIHGWTQSYT--ASMNKDIRSAWLSRGD---YNVIVVDWARARSVD--YATSVLAVAATGKKVAKMINFLKDNHGLNLND-LYVIGHSLGAHVAGYAGKNTDG----QVHTIIGLDPALPLFSYNK-PNKRLNSDDAWYVESIQTNG------GTLGFLKPIGKGAFYPNGGK-TQPGCGLDLTG-------------------ACSHGRSTTYYAEAVSE-DNFGTMKCGDYEEAVSKECG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STYSSVRMG----------------------------------ADTNAYMVEGDYYVPVNSKAPFGMIN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB88-1", "uniprot_id": "Q9VB88_DROME", "id": "Q9VB88-1", "name": "Lipase domain-containing protein", "aln": "--MKTFLILAIFALAASAYALEESERVNGE------------------------------------NGWYVPQQDGSFEWVDMDVAEEWMEAQEKLEGRGLTTVPVNFYLFTPKNPSSSKHIYATTK------------------------------------SISKSNFNPAH---------------------PTRFVIHGWTQSYL--NSMNSDIRKAFLSKGD---YNVIVVDWARARSVD--YATSVMAVAATGKKVAKMINFLKDNHGLNLND-VYVIGHSLGAHVAGYAGKNTDG----QVHTIIGLDPALPLFSYNK-PNKRLNSDDAWYVESIQTNG------GTLGFLKPIGKGAFYPNGGK-TQPGCPLDVTG-------------------ACSHGRSTTYYAEAVSE-DNFGTMKCGDYEEAVAKECG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STYSSVRMG----------------------------------ADTNAYMVEGDFYVPVNSKAPFGMIN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1ZAL5-1", "uniprot_id": "A1ZAL5_DROME", "id": "A1ZAL5-1", "name": "Lipase domain-containing protein", "aln": "----------MVLTAASTLCN-----------------------------------------------VFTFLLAGSPIFYSAAPRGSCSTCCAIK-----EREDIKFMLYTSRNRNSAQLLHLSDD-----------------------------------ARLAQSNFNFNY---------------------PLAIYLHGFSESATGERQSSQELKDAFLRRGN---YNVILIDWSAMTAVPW-YSNAVENLPVSGRYLARFLRFLVDKG-YPAKY-IHLIGFSLGAEVAGFAGKQLQEWG-IKLPRITALDPALPLFEGNS-SNRRLSPSDARFVDVIHTDG------GLLGNPAPMGHADFYPNGGRPLQPGCAKQNIANNWLG-----------IIVGCSHQRAWEYFVESIAQPRGFPAQRCEPSDMFGICREP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGGPAFMG-----------------------------------MGADPRIRGKFYLDTNDAKPFGRNSR-------------------------------------------ARAIVSLAPRLPIAYKLPPNATRQPSVSRWANGQKEQ--------------DNEDEDNNALSNNIDRFSLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8DYT7-1", "uniprot_id": "A8DYT7_DROME", "id": "A8DYT7-1", "name": "Lipase domain-containing protein", "aln": "----------MSIYSTLILLLTIVSG----------------------------------------------------FCKGENHTRGWLPEFCVVGEQKCPNSRVSFWLYTNQTRDDPIQLDPLNP----------------------------------QKDVFQPRL-------------------------PLKILIHGFIGNRN--LTPNLEVRDVLLQTQP---INVISVDYGTLVRWPCYYPWAVNNAPIVSECLAQMINNLISAGISRRED-IHLIGFSLGAQVAGMVANYVSQP----LARITGLDPAGPGFMMQPSLQQKLDASDADFVDIIHTDP------FFFSMLPPMGHADFYPNLDQLNQRGCSYISNWR----------------FYNCNHYRAAVYYGESIISERGFWAQQCGGWFDFFSQRCS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HYSNMPNTQMG-----------------------------------YFVSEDASGSYFLTTHEVAPFA-----------------------------------------------KGPLVEVEFDVSELRNFTEIELR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W448-1", "uniprot_id": "Q9W448_DROME", "id": "Q9W448-1", "name": "Lipase domain-containing protein", "aln": "--MYVANTTGGLMLQTMLYLANHTSRAAVN--------------------------TLVDLPPAPKSDINEVKCFGVYGCFPINGPWNTVTRSINVHPQKPSEIEPHFTLHTRRALDQPKYLDLNDP-----------------------------------ESVQGMGMNPKG---------------------KIFLLVHGYLESGE--IPWMWDMAKALLAHEPEGRASVVLIDWGGGASPP--YVQAVANIRLVGAITAHVVHMLYEELRLPNLDNVHIIGHSLGAHLSGYAGYHLQHDFGLKPARITGLDPAAPLFTDTD-PIVRLDKTDAHFVDIVHTDAN-PLMKGGLGINMRLGHVDFFPNGGF-DNPGCNKKFQDVVKKKTLFLT----MQEFLGCNHIRSQQYFTESIGSQCPFLGITCDSFESFKDTKCTSCEE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGHTCLRMGYHSQE---------------------DYQEQVDLGQLQQGDSPGVFYLWTGDSKPFCRLHYRITVRVSGHDESTLHGGEVGILSIQLHDALVKKAGKNERAATEMMKFSQKAMYFEPGYEYKALVAGRNLREPEYATVNWEYPTNILNPLTWRILSAPRIYLEYILIEAMESSDLYLKLCPQHEGAILTGAENVLRSSYCKD-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU78-1", "uniprot_id": "Q9VU78_DROME", "id": "Q9VU78-1", "name": "Lipase domain-containing protein", "aln": "------------------------------------------------------------------------------------MQTGVQLALFLTLTIAAVYGETGFFLNTRRVQENAQPIEAEVE------------------------------------ALVRSSFYAAD---------------------PTVVTIPRWLGNIS--SPEIPAVVSARLQQQD---SNIISVDLS-----------EANDETEIIDSVASLVIVLHNQFDMPLDR-ILVVGFAEGAHLAGGVAAKVQQDLGRQLSQITALDPSSGAELDHK-----LSQADAEFVEVVHTNA------GGEGTWERLGHVDYYPNGGQ-TQPGCTT----------------------DSCSHERAFELLAEMWSPENDFVSARCGSVETLSASSCR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WSTHKMGQ---------------------------------KQEEEQPASGIYFLETRQSSPFSRGAYFISFL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : : : : . : : : : : :: . . .: * ::*.: **.::* .. * .*** *. ** :*: :::: . *: ::** . ** * * *: : * * :. : ", "identical_positions": 24, "similar_positions": 44, "identity": "2.35%" }, { "cls_id": "homologset.agr.RGD:620793", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54318-1", "uniprot_id": "LIPR2_RAT", "id": "P54318-1", "name": "Pancreatic lipase-related protein 2", "aln": "-------------------MLLCWIVS-LLLATVG------------------------------------------GKEVCYGHLGCFSNDKPWAGMLQRPLKIFPWSPEDIDTRFLLYTNENPNNYQKISATEP-----------------------------------DTIKFSNFQLDR---------------------KTRFIVHGFIDKGEDGWLLDMCKKMFQVE---KVNCICVDWRRGS-RTEYTQASYNTRVVGAEIAFLVQVLSTEMGYS-PENVHLIGHSLGAHVVGEAG---RRLEG-HVGRITGLDPAEP-CFQGLPEEVRLDPSDAMFVDVIHTDSAPIIPYLGFGMSQKVGHLDFFPNGGKE-MPGCQKNILSTIVDING---IWEGTQNFVACNHLRSYKYYASSILNPDGFLGYPCSSYEKFQQNDCFPCPEEG---------CPKMGHYADQFEG-------------------------------------------KTATVEQTVYLNTGDSGNFTR-------------------------------------WRYKVSVTLSGAKKLSGYILVALYGNNGNSKQYEIFKG---------------------SLKPEARHVRDIDVDINVGEIQKVKFLWNNKVIN---------------------------------------------------------------LFRPTLGASQITVQSGVDGKEYNFCSSDTVREDVLQSLYPC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17892-1", "uniprot_id": "LIPR2_MOUSE", "id": "P17892-1", "name": "Pancreatic lipase-related protein 2", "aln": "-----MPMDVRGCLFPSVQMLLCWLVS-LLLATVG------------------------------------------GKEVCYGHLGCFSNDKPWAGMIQRPSKIFPWSPEDIDTRFLLYTNENPNNYQIISATDP-----------------------------------ATINASNFQLDR---------------------KTRFIIHGFIDKGEEGWLLDMCKKMFQVE---KVNCICVDWKRGS-RTEYTQASYNTRVVGAEIAFLVQVLSTEMGYS-PENVHLIGHSLGSHVAGEAG---RRLEG-HVGRITGLDPAEP-CFQGLPEEVRLDPSDAMFVDVIHTDSAPIIPYLGFGMSQKVGHLDFFPNGGKE-MPGCQKNILSTIVDING---IWEGTRNFAACNHLRSYKYYASSILNPDGFLGYPCSSYEKFQHNDCFPCPEQG---------CPKMGHYADQFEG-------------------------------------------KTATVEQTFFLNTGDSGNFTR-------------------------------------WRYKVSVTLSGAKKLSGYILVALYGCNGNSKQYEVFKG---------------------SLQPEARYIRDIDVDVNVGEIQKVKFLWNNKVIN---------------------------------------------------------------LFRPTMGASQITVQRGKDGKEFNFCSSNTVHEDVLQSLYPC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54317-1", "uniprot_id": "LIPR2_HUMAN", "id": "P54317-1", "name": "Pancreatic lipase-related protein 2", "aln": "-------------------MLPPWTLGLLLLATVR------------------------------------------GKEVCYGQLGCFSDEKPWAGTLQRPVKLLPWSPEDIDTRFLLYTNENPNNFQLITGTEP-----------------------------------DTIEASNFQLDR---------------------KTRFIIHGFLDKAEDSWPSDMCKKMFEVE---KVNCICVDWRHGS-RAMYTQAVQNIRVVGAETAFLIQALSTQLGYS-LEDVHVIGHSLGAHTAAEAG---RRLGG-RVGRITGLDPAGP-CFQDEPEEVRLDPSDAVFVDVIHTDSSPIVPSLGFGMSQKVGHLDFFPNGGKE-MPGCKKNVLSTITDIDG---IWEGIGGFVSCNHLRSFEYYSSSVLNPDGFLGYPCASYDEFQESKCFPCPAEG---------CPKMGHYADQFKG-------------------------------------------KTSAVEQTFFLNTGESGNFTS-------------------------------------WRYKISVTLSGKEKVNGYIRIALYGSNENSKQYEIFKG---------------------SLKPDASHTCAIDVDFNVGKIQKVKFLWNKRGIN---------------------------------------------------------------LSEPKLGASQITVQSGEDGTEYNFCSSDTVEENVLQSLYPC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VX01-1", "uniprot_id": "Q9VX01_DROME", "id": "Q9VX01-1", "name": "Lipase domain-containing protein", "aln": "---------MLSASYIILAMLMCHTVNAIAQEVARTVPTAPSPAHFAELSQAVHDQLMEHEERQRERVRRGHRSRRAVKRVCYGELGCFEDSGPFA-----YLEMLPSSPEEINTKFYFYSTRQRSDRPLMELSFLNMTNAFRGKRETEVSTSSPEGTSGRSSVASAPSSMSAVNATTFTTERPGGGQKKPTPSIDDLEGFDELSVRVIVHGFGSACPHVWIYEMKTALMAVE---DCIVICVDWENGATFPNYVRAAANTRLVGKQLAMLLRNLQQHKGLD-LMRTHVIGFSLGAHVSGFAG---AELPG--LSRITGLDPAGP-LFEAQHPKVRLDSSDAEFVDVIHSNGENLILG-GLGSWQPMGHVDYYPNGGRV-QTGCSNLFVGAVTDFIWSAQAAEDEEGRSLCNHRRAYKFFIDSVAPRCLFPAFPCGNYDDFLKGRCFPCAQDDEDLAEGVPRCGNMGYYADRSTGRGQLYLLTREEEPFCAHQFQLQIFNSFNDLPLRTIGRLEAILEGDGGLNETFEISEKDDAEFFAGDIVSKIIVPHPALGFPTTLSLHYKSYSGWLSKGLPHWDIDKVVLTDSFGRSHSLCRPSTKLSSGSPVRLRLQAGNCELDNQEDYGAYTTQPPAAPPAQHAGNPTVAVPTDVPDSSVQESGLAASVDGVESAKQRKDIFNLGTSFKLARNQTYPLDQGDELPWQPILVGNSLDNETAEAAESSRSLSDSIAGEIFEPVLKDRRLAVNRGRNLQDYATTDSPEIMEPVLKATTPRVKQGKDLDLSESELAAGMVTTLGAITSAVAGSSRLPAKTMAQVGTGRSPDPDEPQTVQLLPFRLGELLQRAERYARETLLPLISVQAPRFFGFNVTPHDREPVRPGESRKPRYIPRYEESAFLNTSSNARRRSQKASRRSSAQQRNLLRLVRARSHGLDDGEDGSDEQREGEREQRNEVNYYTNVLQSESRSMRPEAPEYRPVFIDLPTYKPKTAAAFSTSAAVSAPLASAAVSGSVSLSRARRRGRSPKLIP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB91-1", "uniprot_id": "Q9VB91_DROME", "id": "Q9VB91-1", "name": "Lipase domain-containing protein", "aln": "-----------MRVFIALAALLATVSALPIEE--RVNGE------------------------------------NGWYVPQIDGSFEWMDKQDAEELLNRNSLIETRS---NDVSFYLYTKHNPTVGKEIRADAS------------------------------------SIEDSHFDKNQ---------------------GTRFVIHGWNGRYTDGMNVKITRAWLSKG---DYNVIVVNWDRAQ-SVDYISSVRAVPGAGAKVGEMIEYLHEHHHLS-MESLEVIGHSLGAHVAGYAG---KQVGGKRVHTIVGLDPAMP-LFAYDKPDKRLSTEDAFYVESIQTNGG------EKGFLKPIGKGTFYPNGGRN-QPGCGSDIGG-------------------TCAHGRSVTYYVEAVTE-DNFGTIKCHDYQAALANECG----------------------------------------------------------------------------------------------------------------------------------------------------------STYSGVRMGAVTN---------------------AYMVDGDFYVPVNGQAPFGKIE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB90-1", "uniprot_id": "Q9VB90_DROME", "id": "Q9VB90-1", "name": "Lipase domain-containing protein", "aln": "-----------MKVFFVLAALLAAVSALPIEE--RVNGE------------------------------------NGWFIPKLDGSFEWMDMQDAEDLLANGAQMEGRIST-NAVNFYVYTKSNPTDGKEIKAKSG------------------------------------SVEDSHFNKDH---------------------GTRFVIHGWTQRYSDDMNTRITKAWLSKG---DYNVIVVDWARAR-SVDYASSVLAVPGAGGKVGEMIKYLHDHHGLD-YDSLEVIGHSLGAHVAGYAG---KTVGDKRVHTIVGLDPALP-LFSYDKPAKRLSTDDAHYVESIQTNGG------KLGFLKPIGKGAFYPNGGKS-QPGCGLDATG-------------------SCSHARSVLYYAEAVTE-DNFGSIKCHDYEDAVAKNCG----------------------------------------------------------------------------------------------------------------------------------------------------------STYSSVRMGAITN---------------------AYMVEGDFYVPVNSEAPFGKIE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB89-1", "uniprot_id": "Q9VB89_DROME", "id": "Q9VB89-1", "name": "Lipase domain-containing protein", "aln": "-----------MKTFLILAFFALAASAIPIKESERVHGE------------------------------------NGWYVPQEDGTSEWVDMDVAEQWMEAQELLESRGLTTVPVKFYLYTSSNPTKGKKITASTK------------------------------------SIDASSFNSAH---------------------PTRFVIHGWTQSYTASMNKDIRSAWLSRG---DYNVIVVDWARAR-SVDYATSVLAVAATGKKVAKMINFLKDNHGLN-LNDLYVIGHSLGAHVAGYAG---KNTDG-QVHTIIGLDPALP-LFSYNKPNKRLNSDDAWYVESIQTNGG------TLGFLKPIGKGAFYPNGGKT-QPGCGLDLTG-------------------ACSHGRSTTYYAEAVSE-DNFGTMKCGDYEEAVSKECG----------------------------------------------------------------------------------------------------------------------------------------------------------STYSSVRMGADTN---------------------AYMVEGDYYVPVNSKAPFGMIN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB88-1", "uniprot_id": "Q9VB88_DROME", "id": "Q9VB88-1", "name": "Lipase domain-containing protein", "aln": "-----------MKTFLILAIFALAASAYALEESERVNGE------------------------------------NGWYVPQQDGSFEWVDMDVAEEWMEAQEKLEGRGLTTVPVNFYLFTPKNPSSSKHIYATTK------------------------------------SISKSNFNPAH---------------------PTRFVIHGWTQSYLNSMNSDIRKAFLSKG---DYNVIVVDWARAR-SVDYATSVMAVAATGKKVAKMINFLKDNHGLN-LNDVYVIGHSLGAHVAGYAG---KNTDG-QVHTIIGLDPALP-LFSYNKPNKRLNSDDAWYVESIQTNGG------TLGFLKPIGKGAFYPNGGKT-QPGCPLDVTG-------------------ACSHGRSTTYYAEAVSE-DNFGTMKCGDYEEAVAKECG----------------------------------------------------------------------------------------------------------------------------------------------------------STYSSVRMGADTN---------------------AYMVEGDFYVPVNSKAPFGMIN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W448-1", "uniprot_id": "Q9W448_DROME", "id": "Q9W448-1", "name": "Lipase domain-containing protein", "aln": "MYVANTTGGLMLQTMLYLANHTSRAAVNTLVDLPPAPKS------------------------------------DINEVKCFGVYGCFPINGPWN-TVTRSINVHPQKPSEIEPHFTLHTRRALDQPKYLDLNDP-----------------------------------ESVQGMGMNPKG---------------------KIFLLVHGYLESGEIPWMWDMAKALLAHEPEGRASVVLIDWGGGA-SPPYVQAVANIRLVGAITAHVVHMLYEELRLPNLDNVHIIGHSLGAHLSGYAGYHLQHDFGLKPARITGLDPAAP-LFTDTDPIVRLDKTDAHFVDIVHTDANPLMKG-GLGINMRLGHVDFFPNGGFD-NPGCNKKFQDVVKKKT----LFLTMQEFLGCNHIRSQQYFTESIGSQCPFLGITCDSFESFKDTKCTSCEEPG----------------------------------------------------------------------------------------------------------------------------HTCLRMGYHSQEDYQEQVDLGQLQQGDSPGVFYLWTGD-------------SKPFCRLHYRITVRVSGHDESTLHGGEVGILSIQLHDALVKKAGKNER-------------------------------------------AATEMMKFSQKAMYFEPGYEYKALVAGRNLREPEYATVNWEYPTN-ILNPLTWRILSAPRIYLEYILIEAMESSDLYLKLCPQHEGAILTGAENVLRSSYCKD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU78-1", "uniprot_id": "Q9VU78_DROME", "id": "Q9VU78-1", "name": "Lipase domain-containing protein", "aln": "-----------MQTGVQLALFLTLTIA-----------------------------------------------AVYG-----------------------------------ETGFFLNTRRVQENAQPIEAEVE------------------------------------ALVRSSFYAAD---------------------PTVVTIPRWLGNISSPEIPAVVSARLQQQ---DSNIISVDLSEAN----------DETEIIDSVASLVIVLHNQFDMP-LDRILVVGFAEGAHLAGGVAAKVQQDLGRQLSQITALDPSS-----GAELDHKLSQADAEFVEVVHTNAG------GEGTWERLGHVDYYPNGGQT-QPGCTT----------------------DSCSHERAFELLAEMWSPENDFVSARCGSVETLSASSCR------------------------------------------------------------------------------------------------------------------------------------------------------------WSTHKMGQKQEE--------------------EQPASGIYFLETRQSSPFSRGAYFISFL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8DYT7-1", "uniprot_id": "A8DYT7_DROME", "id": "A8DYT7-1", "name": "Lipase domain-containing protein", "aln": "-----------MSIYSTLILLLTIVSG------------------------------------------------------------FCKGENHTRGWLPEFCVVGEQKCPNSRVSFWLYTNQTRDDPIQLDPLNP--------------------------------------QKDVFQPRL---------------------PLKILIHGFIGNRNLTPNLEVRDVLLQTQ---PINVISVDYGTLVRWPCYYPWAVNNAPIVSECLAQMINNLISAGISRREDIHLIGFSLGAQVAGMVA----NYVSQPLARITGLDPAGPGFMMQPSLQQKLDASDADFVDIIHTDPF------FFSMLPPMGHADFYPNLDQLNQRGCSYISNWR----------------FYNCNHYRAAVYYGESIISERGFWAQQCGGWFDFFSQRCS--------------------------------------------------------------------------------------------------------------------------------------------------------HYSNMPNTQMGYFVS----------------------EDASGSYFLTTHEVAPFAKGPLVEVEFDVSELRNFTEIELR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : : : . : : : : : :: : ::*.: *:: . .. . * .***: :*. ** :*: :::: . :*: ::** . ** * * *: . * * . * . ", "identical_positions": 22, "similar_positions": 43, "identity": "2.14%" }, { "cls_id": "homologset.agr.RGD:620794", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ES54-1", "uniprot_id": "NPL4_RAT", "id": "Q9ES54-1", "name": "Nuclear protein localization protein 4 homolog", "aln": "-----------------------------MAESIIIRVQSPDGVKRITATKRETAATFLKKVAKEFGF--QNNGFSVYINRNK-TGEITASSSKSLHLLKIKHGDLLFLFPSSLAGPSSE----METSTSVGLKAFGAP------------HVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLEPFDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGK-----FVALENISCKIKSGCEG-HLPWPNGICTKCQPSAITLNRQKYRHVDNIMFENHTVADRFLDFWRKTGNQHFGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIGTQNSLELLEDPK---AEVVDEIASKLGLRKVGWIFTDLVSEDTRKGTVRYSRNKDTYFLSSEECITAGDFQNKHPNICRLSPDGHFGSKFVTAVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCKDAPELGYAKESSSEQYVPDVFYKDIDKFGNEITQLARP-LPVEYLIIDITTTFPKDPVYTFSIS--QNPFPIENRDVLGETQDFHSLATYLSQNTSS----VFLDTISDFHLLLFLVTNEVMPLQDSISLLLEAVRTRNEELAQTWKKSEQWATIEQLCSTVGVQLPGLHEFGAVGGSARAATS---------AMWACQHCTFMNQPGTGHCEMCSLPRT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60670-1", "uniprot_id": "NPL4_MOUSE", "id": "P60670-1", "name": "Nuclear protein localization protein 4 homolog", "aln": "-----------------------------MAESIIIRVQSPDGVKRITATKRETAATFLKKVAKEFGF--QNNGFSVYINRNK-TGEITASSSKSLHLLKIKHGDLLFLFPSSLAGPSSE----METSTSVGLKAFGAP------------NVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLEPFDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGK-----FVALENISCKIKSGCEG-HLPWPNGICTKCQPSAITLNRQKYRHVDNIMFENHTVADRFLDFWRKTGNQHFGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIGTQNSLELLEDPK---AEVVDEIAAKLGLRKVGWIFTDLVSEDTRKGTVRYSRNKDTYFLSSEECITAGDFQNKHPNICRLSPDGHFGSKFVTAVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCKDAPELGYAKESSSEQYVPDVFYKDIDKFGNEITQLARP-LPVEYLIIDITTTFPKDPVYTFSIS--QNPFPIENRDVLGETQDFHSLATYLSQNTSS----VFLDTISDFHLLLFLVTNEVMPLQDSISLLLEAVRTRNEELAQTWKKSEQWATIEQLCSTVGVQLPGLHEFGAVGGSARAATS---------AMWACQHCTFMNQPGTGHCEMCSLPRT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAT6-1", "uniprot_id": "NPL4_HUMAN", "id": "Q8TAT6-1", "name": "Nuclear protein localization protein 4 homolog", "aln": "-----------------------------MAESIIIRVQSPDGVKRITATKRETAATFLKKVAKEFGF--QNNGFSVYINRNK-TGEITASSNKSLNLLKIKHGDLLFLFPSSLAGPSSE----METSVPPGFKVFGAP------------NVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLEPFDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGK-----FVALENISCKIKSGCEG-HLPWPNGICTKCQPSAITLNRQKYRHVDNIMFENHTVADRFLDFWRKTGNQHFGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIGTQNSLELLEDPK---AEVVDEIAAKLGLRKVGWIFTDLVSEDTRKGTVRYSRNKDTYFLSSEECITAGDFQNKHPNMCRLSPDGHFGSKFVTAVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCKDAPELGYAKESSSEQYVPDVFYKDVDKFGNEITQLARP-LPVEYLIIDITTTFPKDPVYTFSIS--QNPFPIENRDVLGETQDFHSLATYLSQNTSS----VFLDTISDFHLLLFLVTNEVMPLQDSISLLLEAVRTRNEELAQTWKRSEQWATIEQLCSTVGGQLPGLHEYGAVGGSTHTATA---------AMWACQHCTFMNQPGTGHCEMCSLPRT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VBP9-1", "uniprot_id": "NPL4_DROME", "id": "Q9VBP9-1", "name": "Nuclear protein localization protein 4 homolog", "aln": "MACAPLLLEQFIYKKRNFAYAFVRHRLFVLCKQSLIRVQSAEGIKRIEISPKSNLKHLYDSVQNAL----KVDGFGLFKERNF-LTELQASGSQ-LVGTSLRHGDMVYLK--QMAGTSSR----RTSTTVLDSQAFKTSTISNPNSARPSFNVIEDDVDQALSKADGTIKRERDSKLCHHNANGRCVHCSALEPYDESYLKEHN--IKHLSFHSYIRKQTSGMDQGK-----YFVFDDINCRIKPGCRE-HPPWPKGICSKCQPSAITLNRQTYRHVDNVMFENTKIVERFLNYWRTTGHQRMGYLYGTYEQHTDVPLGIRAKVAAIYEPPQESTRDSINIQPDEF---ADDVDAVASALGLKKIGWIFTDLITDDASIGTVKQIRGIESHFITAQECITAGELQNRHPNPCKYASNGVFGSKFVTICVTGDKTKQVHMEGYAVSAQCMALVRDNCLIPTKDAPELGYVRESTDKQYVPDVFYKEKDLYGNEVQRLARP-LPVEYLLVDVPASTPLQPIYTFTEYDKRQPFPIENRYIDGHLQDFNALSCYLSAWGEE----EFLEAISDFHLLVYLYKMDMLPLRQHMGPLLEAVRTKNPNQAAQFKVVDVWKLLESLIQASSGGSGGTTSYPSGGASASAGASGSEAMDLDANTWTCNHCTFINRGELTSCEICSLPR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33755-1", "uniprot_id": "NPL4_YEAST", "id": "P33755-1", "name": "Nuclear protein localization protein 4", "aln": "---------------------------------MLIRFRSKNGTHRVSCQENDLFGTVIEKLVGNLDPNADVDTFTVCEKPGQGIHAVSELADRTVMDLGLKHGDMLILNYSDKPANEKDGVNVEIGSVGIDSKGIRQHRYG-------PLRIKELAVDEELEKEDGLIPRQK-SKLCKHGDRGMCEYCSPLPPWDKEYHEKNK--IKHISFHSYLKKLNENANKKENGSSYISPLSEPDFRINKRCHNGHEPWPRGICSKCQPSAITLQQQEFRMVDHVEFQKSEIINEFIQAWRYTGMQRFGYMYGSYSKYDNTPLGIKAVVEAIYEPPQHDEQDGLTMDVEQVKNEMLQIDRQAQEMGLSRIGLIFTDLSDAGAGDGSVFCKRHKDSFFLSSLEVIMAARHQTRHPNVSKYSEQGFFSSKFVTCVISGNLEGEIDISSYQVSTEAEALVTADMIS-GSTFPSMAYINDTTDERYVPEIFYMKSNEYGITVKENAKPAFPVDYLLVTLTHGFPNTDTETNSKFVSSTGFPWSNRQAMGQSQDYQELKKYLFNVASSGDFNLLHEKISNFHLLLYINSLQILSPDEWKLLIESAVKNEWEESLLKLVSSAGWQTLVMILQESG---------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**.:* :* :*: .. . ..: : . : * : : . : ..: : ::***:: * . .. .. :. . : : .: * :*: *.* ** * *.: .:**:*. * * :* .* *:*:.* :. : :**:***:*::* . . :: : :.: . :*: *. * ***.***:*********::* :* **:: *:: : :.*:: ** ** *::**:** * :: : ****:* * ******* . ::.: : : :* * :** ::* ***** .: *:* * ::.*::: * * *. *.:*** .: : :* *.***** :*. ::.:..* ** :. *** : : . *.:.* .:::.::***::** . : :* : . *:* :**:**:: :. * * : ** .** *. **:: * ** .. : : **:****::: . :::. : : .**:.. : * : : . . ", "identical_positions": 152, "similar_positions": 188, "identity": "22.32%" }, { "cls_id": "homologset.agr.RGD:620795", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUD9-1", "uniprot_id": "SRC_RAT", "id": "Q9WUD9-1", "name": "Proto-oncogene tyrosine-protein kinase Src", "aln": "MG----SNKSKPKDASQRRRSLEPAENVHGAGG-AFPASQTPSKPASADGHRGPNAAFVPPAAAEPKLFGGFNSSD-TVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP-TSKPQTQGLAK---DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKGETG--KYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05480-2", "uniprot_id": "SRC_MOUSE", "id": "P05480-2", "name": "Proto-oncogene tyrosine-protein kinase Src", "aln": "MG----SNKSKPKDASQRRRSLEPSENVHGAGG-AFPASQTPSKPASADGHRGPSAAFVPP-AAEPKLFGGFNSSD-TVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP-TSKPQTQGLAK---DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMNKGSLLDFLKGETG--KYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P12931-1", "uniprot_id": "SRC_HUMAN", "id": "P12931-1", "name": "Proto-oncogene tyrosine-protein kinase Src", "aln": "MG----SNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPA-AAEPKLFGGFNSSD-TVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCP-TSKPQTQGLAK---DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMSKGSLLDFLKGETG--KYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1JPZ3-1", "uniprot_id": "SRC_DANRE", "id": "Q1JPZ3-1", "name": "Proto-oncogene tyrosine-protein kinase Src", "aln": "MG----GVKSKPKELGQRSRSLDDGTGGHHHHT-PNPTSFTPNRSPPVEGSRRGTQPNIIN--AEQALFGGVNSTTNSITSPNRIG-ILGGVTTFVALYDYESRTASDLSFRKGERLQIVNNTEGDWWLARSLTTGESGYIPSNYVAPSDSIQAEEWYFGKITRRDSERLLLNLENRRGTFLVRESETTKGAYCLSVLDYDNVKGLNVKHYKIRKLDSGGFYITSRTQFSTLQQLVNHYRQHADGLCHSLTDVCP-VLKPPTQGLAR---DAWEIPRDSLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMGQGSLLDFLKGDMG--KMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPAECPDSLHELMLTCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQPGENL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9J3-1", "uniprot_id": "SRC42_DROME", "id": "Q9V9J3-1", "name": "Tyrosine-protein kinase Src42A", "aln": "MGNCLTTQKGEPDKPADRIKLDDPPTIGVGVG--------VPQIPMPSHAGQPPEQIRPVP----------------QIPESETAG---ANAKIFVALYDYDARTDEDLSFRKGEHLEILNDTQGDWWLARSKKTRSEGYIPSNYVAKLKSIEAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRDGD-----TVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFYTSDQSDYKEAQAY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.:*.. .:* : : .*. . . .. : :...: * .... *******::** ****:***:*:*:*:*:******:* .* . ********* .**:** *** **.* ::*: ** ** :*:**:*:**: :. *.*** * * .****:**:**.***:*: ** * :**:** :* :.:**** * * ** *:**:: * *** * **:: ***.* **:** * **.** *******.***.*: ** ***:****** **:***** : ******:** * :****::*:. * : *:: *:**::***:****:* **:**** * *:***:. : *:*********:::** ** **:*********** *.:*:***************.* **:*****.* *** ***:***** *.:* *:::* **:*:* .***** ** ***::** :.:*: .: ", "identical_positions": 274, "similar_positions": 122, "identity": "49.91%" }, { "cls_id": "homologset.agr.RGD:620796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19623-1", "uniprot_id": "SPEE_HUMAN", "id": "P19623-1", "name": "Spermidine synthase", "aln": "---------------------MEPGPDGPAASGPAAIREGWFRETCS-LWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG----------------------NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMA---------------------IGYSSSKLTLHVGDGFEFMKQN-----------------------------------------QDAFDVIITDSSDPMG-------------------------------------PAESLFKESYYQLMKTALKEDGVLCCQ--------------------------GECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSK-NPSTNFQEPVQPLTQQQVAQMQLK--------------YYNSDVHRAAFVLPEFARKALNDVS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64674-1", "uniprot_id": "SPEE_MOUSE", "id": "Q64674-1", "name": "Spermidine synthase", "aln": "---------------------MEPGPDGPAAPGPAAIREGWFRETCS-LWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYG----------------------NVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIEVSKKFLPGMA---------------------VGFSSSKLTLHVGDGFEFMKQN-----------------------------------------QDAFDVIITDSSDPMG-------------------------------------PAESLFKESYYQLMKTALKEDGILCCQ--------------------------GECQWLHLDLIKEMRHFCKSLFPVVDYAYCSIPTYPSGQIGFMLCSK-NPSTNFREPVQQLTQAQVEQMQLK--------------YYNSDMHRAAFVLPEFTRKALNDIS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VHA1-1", "uniprot_id": "Q9VHA1_DROME", "id": "Q9VHA1-1", "name": "", "aln": "---------------------MDS------------LNNGWFSELQADLWPGQSFSLKVKEVIHKEKSRFQDIQIVETETYG----------------------RCLILDGIIQCTARDEFSYQEMISFLPLCAHPNPKKVLIVGGGDGGVAREVVKHPLVEEVHQVEIDDRVVELSKQYLPAMA---------------------CGFANEKLKLTIGDGFDYMKKH-----------------------------------------KNEFDVIITDSSDPIG-------------------------------------PAVSLFQESYYELMKHALKDDGIVCSQ--------------------------GGSFWLDLDYIKKTMSGCKEHFAKVAYAVTSVPSYPCGHIGFVMGSL-NKNQDFATP--KLGKSEIDSIDLR--------------YYSSEVHSAAFALPRWVQKHFYE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12455-1", "uniprot_id": "SPSY_YEAST", "id": "Q12455-1", "name": "Spermine synthase SPE4", "aln": "---------------------MVNNSQHP------YIKDGWFREINDKSFPGQAFTMTVDSILYEARSEFQDILIFRNKVYG----------------------TVLVLDGIVQCTEFDEFAYQEMITHIAMFAHSNPKRVLIIGGGDGGVLREVAKHSCVEDITMVEIDSSVIELSRKFLPTLSN--------------------GAFDDERLDLKLCDGFKFLQDIGA------------------------------------SDVHKKFDVIITDSSDPEG-------------------------------------PAEAFFQERYFELLKDALNPNGVVIMQS-------------------------SENFWLNLKYLHDLKNTAKKVFPNTEYCYTMVPTYTSGQLGLIVCSN-NANIPLNIPQRKIS--EQEQGKLK--------------YYNPQIHSSAFVLPTWADKVINE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12074-1", "uniprot_id": "SPEE_YEAST", "id": "Q12074-1", "name": "Spermidine synthase SPE3", "aln": "---------------------MAQEITHP------TIVDGWFREISDTMWPGQAMTLKVEKVLHHEKSKYQDVLIFKSTTYG----------------------NVLVLDNVIQATERDEFAYQEMIAHLALNSHPNPKKVLVIGGGDGGVLREVVKHDSVEEAWLCDIDEAVIRLSKEYLPEMA---------------------ASYSHPKVKTHIGDGFQFLRDY-----------------------------------------QNTFDVIITDSSDPEG-------------------------------------PAETLFQKEYFQLLNSALTEKGVITTQ--------------------------AESMWIHLPIIKDLKKACSEVFPVAEYSFVTIPTYPTGTIGFMVCSK-DKTCNVKKPLREISD-EKEAELYR--------------YYNKKIHEASFVLPTWAAKELN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9JJS8-1", "uniprot_id": "MASP2_RAT", "id": "Q9JJS8-1", "name": "Mannan-binding lectin serine protease 2", "aln": "MRLLIVLGLLWSLVATLLGSKWPEPVFGRLVSLGFPEKYGNHQDRSWTLTAPPGFRLRLYFTHFNLELSYRCEYDFVKLTSGTKVLATLCGQESTDTERAPGNDTFYSLGPSLKVTFHSDYSNEKPFTGFEAFYAAEDVDECRTSLGDS-VPCDHYCHNYLGGYYCSCRVGYILHQNKHTCSALCSGQVFTGRSGFLSSPEYPQPYPKLSSCAYNIRLEEGFSITLDFVESFDVEMHPEAQCPYDSLKIQTDKREYGPFCGKTLPPRIETDSNKVTITFTTDESGNHTGWKIHYTSTAQPCPDPTAPPNGHISPVQATYVLKDSFSVFCKTGFELLQGSVPLKSFTAVCQKDGSWDRPIPECSIIDCGPPDDLPNGHVDYITGPEVTTYKAVIQYSCEETFYTMSSNGKYVCEADGFWTSSKGEKSLPVCKPVCGLSTHTSGGRIIGGQPAKPGDFPWQVLLLGETTAAGALIHDDWVLTAAHAVYGKTEAMSSLDIRMGILKRLSLIYTQAWPEAVFIHEGYTHGAGFDNDIALIKLKNKVTINRNIMPICLPRKEAASLMKTDFVGTVAGWGLTQKGFLARNLMFVDIPIVDHQKCATAYTKQPYPGAKVTVNMLCAGLDRGGKDSCRGDSGGALVFLDNETQRWFVGGIVSWGSINCGGSEQYGVYTKVTNYIPWIENIINNF", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . .: : : .. . :: . . . * *. :: * .::: :: :: : .: . **. * : * : ::. .:. . :. : :**. . . .* ** ::* * : :.* : ::*:: :: ... . :: : . . * .* *: * : . . * : . .:: :. . ", "identical_positions": 22, "similar_positions": 82, "identity": "3.21%" }, { "cls_id": "homologset.agr.RGD:620797", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51047-1", "uniprot_id": "MR1AL_DANRE", "id": "P51047-1", "name": "Melatonin receptor type 1A-like", "aln": "------------------------------------------------------------------------------------------------------------------------------------CHSLKYDKLFSNKNTVCYVILVWALTVLAIVPNWFVESLQYDPRVFSCTFAQSVSSLYTIMVVVVHFIVPIGIVTYCYLRIWILVIQVPRRVKPDSRPKIKPHDFRNFLTMFVVFVLFAVCWAPLNFIGLAVAIHP-RLGQSIPEWLFTASYF--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P51046-1", "uniprot_id": "MR1AA_DANRE", "id": "P51046-1", "name": "Melatonin receptor type 1A-A", "aln": "MFMNGSSLN--SSALDPSEQ-ALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDPRVYSCTFEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVLFAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PN98-1", "uniprot_id": "A0A8M9PN98_DANRE", "id": "A0A8M9PN98-1", "name": "", "aln": "MKINGSGLMNSSSLSPHDEN-TLNRPPWVATTLGSFLIFTIVVDILGNLLVIFSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLVSIFHNGWNLGFVHCQISGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSDKNSLCYVLLIWILTVVAIVPNFYVGSLQYDPRVYSCTFAQSASSAYTIAVVFFHFILPIMIVTYCYLRIWILVIQVRRRVKPEFRPKLTPHDIRNFVTMFVVFVLFAVCWAPLNFIGLAVAINPDQVAPLIPEWFFVSSYFMAYFNSCLNAIVYGLLNQNFRREYKKIIISLCTARMFFPESSNDAVERIKSKPSPLMTNNNQVKVDSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49218-1", "uniprot_id": "MTR1A_RAT", "id": "P49218-1", "name": "Melatonin receptor type 1A", "aln": "---------------------------------------------------------------------------------------------------------------------------------CYICHSLKYDRIYSNKNSLCYVFLIWTLTLIAIMPNLQTGTLQYDPRIYSCTFTQSVSSAYTIALVVFHFVVPMIIVTFCYLRIWILVLQVRRRVKPDSKPKLKPQDFRNFVTMFVVFVLFALCWAPLNFIGLIVASDPATMAPRIPEWLFVASYY--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61184-1", "uniprot_id": "MTR1A_MOUSE", "id": "Q61184-1", "name": "Melatonin receptor type 1A", "aln": "MKGNVSELLNATQQAPGGGEGGRPRPSWLASTLAFILIFTIVVDILGNLLVILSVYRNKKLRNSGNIFVVSLAVADLVVAVYPYPLVLTSILNNGWNLGYLHCQVSAFLMGLSVIGSIFNITGIAMNRYCYICHSLKYDKIYSNKNSLCYVFLIWMLTLIAIMPNLQTGTLQYDPRIYSCTFTQSVSSAYTIAVVVFHFIVPMIIVIFCYLRIWVLVLQVRRRVKPDNKPKLKPQDFRNFVTMFVVFVLFAICWAPLNLIGLIVASDPATMVPRIPEWLFVASYYLAYFNSCLNAIIYGLLNQNFRKEYKKIIVSLCTAKMFFVESSNEEADKIKCKPSPLIPNNNLIKVDSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48039-1", "uniprot_id": "MTR1A_HUMAN", "id": "P48039-1", "name": "Melatonin receptor type 1A", "aln": "MQGNGSALPNASQPVLRGD---GARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:::*.**::***:*:* **: *::** . :******::**** **.** *** :*..**::*: ** :******:**:** :*** : :**:.*:*.***:**********:******:*** ** * : ****:*.:**: ", "identical_positions": 92, "similar_positions": 40, "identity": "26.06%" }, { "cls_id": "homologset.agr.RGD:620798", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51049-1", "uniprot_id": "MR1BB_DANRE", "id": "P51049-1", "name": "Melatonin receptor type 1B-B", "aln": "MPENIAFLTNSTDLGHVGRA-------LGS--SARPAWAIAVLASVLIFTTVVDVLGNLLVIISVFRNRKLRN-AGNVFVVSLAFADLVVAFYPYPLVLYAIFHDGWSLGETQCKISGFLMGLSVIGSVFNITGIAINRYCYICHSFAYGRLYSFRNTLLLVALIWALTVLAILPNFF--VGSLSYDPRVYSCTFTQTASSSYTVVVVVVHFLVPIAVVTFCYLRIWVLVIQVRRKVKSEERSRVRPS----------------------DLRNFVTMFVVFVLFAICWAPLNLIGLVVAINPEVMAPRVPEWLFVVSYFMAYFNSCLNAIIYGLLNRNFRKEYVRIMTAVWIPRRFVTETSR-AATDGMRSKPSPAINNNE--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90456-1", "uniprot_id": "MR1BA_DANRE", "id": "Q90456-1", "name": "Melatonin receptor type 1B-A", "aln": "MPENVSLIRNRTEVGQ-GRA-------WGSGAGARPAWVVMVLAGVLIFTSVVDVLGNVLVIISVLRNRKLRN-AGNAFVVSLAFADLLVVCYPYPLVLHAMLHAGWLPGEMECKVSGFLMGASVIGSIFNITAIAINRYCFICQANTYEKIYGRAGTLVLLTLVWVLTAIAILPNLS--LGSLTYDPRVYSCTFSQTTSAGYTIAVVTVHFLLPIAVVTFCYLRIWVLVLRVRRRVTTDVRPRLRPS----------------------ELRHFLTMFVVFVLFAVCWAPLNLIGLAVAVDPPRVGPLVPDWLFVMSYF----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P51046-1", "uniprot_id": "MR1AA_DANRE", "id": "P51046-1", "name": "Melatonin receptor type 1A-A", "aln": "MFMNGS-SLNSSALDP-----------SEQ-ALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQN-AGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLF--VGSLQYDPRVYSCTFEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPH----------------------DVRNFVTMFVVFVLFAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVSVCTARIFFGESSN-EAQERLKSKPSPLMTNNNQVKVDSV-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PN98-1", "uniprot_id": "A0A8M9PN98_DANRE", "id": "A0A8M9PN98-1", "name": "", "aln": "MKINGSGLMNSSSLSP-----------HDENTLNRPPWVATTLGSFLIFTIVVDILGNLLVIFSVYRNKKLRN-AGNIFVVSLAVADLVVAIYPYPLVLVSIFHNGWNLGFVHCQISGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSDKNSLCYVLLIWILTVVAIVPNFY--VGSLQYDPRVYSCTFAQSASSAYTIAVVFFHFILPIMIVTYCYLRIWILVIQVRRRVKPEFRPKLTPH----------------------DIRNFVTMFVVFVLFAVCWAPLNFIGLAVAINPDQVAPLIPEWFFVSSYFMAYFNSCLNAIVYGLLNQNFRREYKKIIISLCTARMFFPESSN-DAVERIKSKPSPLMTNNNQVKVDSV-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49287-1", "uniprot_id": "MTR1B_RAT", "id": "P49287-1", "name": "Melatonin receptor type 1B", "aln": "MPDNSSIANCCAASGLAARPSWPGSAEAEPPETPRAPWVAPMLSTVVIVTTAVDFVGNLLVILSVLRNRKLRN-AGNLFVVNLALADLVVALYPYPLILVAILHDGWVLGEIHCKASAFVMGLSVIGSVFNITAIAINRYWCICHSATYHRACSQWHAPLYISLIWLLTLVALVPNFF--VGSLEYDPRIYSCTFIQTASTQYTMAVVAIHFLLPIAVVSFCYLRIWILVLQARRKAKAERKLRLRPS----------------------DLRSFLTMFAVFVVFAICWAPLNCIGLAVAINPEAMALQIPEGLFVTSYFLAYFNSCLNAIVYGLLNQNFRREYKRILSALWSTGRCFHDASKCHLTEDLQGPVPPAAMATIPVQEGAL-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIQ6-1", "uniprot_id": "MTR1B_MOUSE", "id": "Q8CIQ6-1", "name": "Melatonin receptor type 1B", "aln": "MPENSSIPNCCEASGLAARPSWSGSAGARPPVTARAPWVAPMLSTVVVVTTAVDFVGNLLVILSVLRNRKLRN-AGNLFVVSLALADLVIALYPYPLILVAIIRDGWVLGEAHCKASAFVMGLSVIGSVFNITAIAINRYCCICHSTTYHRVCSHWYTPIYISLVWLLTLVALVPNFF--VGSLEYDPRIYSCTFIQTASTQYTAAVVAIHFLLPMAVVSFCYLRIWVLVLQARRKAKATRKLRLRPS----------------------DLRSFLTMFAVFVVFAICWAPLNCIGLAVAINPEAMALQVPEGLFVTSYFLAYFNSCLNAIVYGLLNQNFRREYKRILLAIWNTRRCIQHASKHCLTEERQGPTPPAARATVPVKEGAL-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49286-1", "uniprot_id": "MTR1B_HUMAN", "id": "P49286-1", "name": "Melatonin receptor type 1B", "aln": "MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRN-AGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFF--VGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPS----------------------DLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPP--IIGVQHQADAL-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NDM2-1", "uniprot_id": "GUTR1_DROME", "id": "Q9NDM2-1", "name": "Protein trapped in endoderm-1", "aln": "MDQDMGMATGYFQDADMQMDEP-----AAATQSIYPHSATLFAAISACVFVTIGVLGNLITLLALLKSPTIREHATTAFVISLSISDLLFCSFSLPLTAVRFFQESWTFGTTLCKIFPVIFYGNVAVSLLSMVGITLNRYILIACHSRYSQIYKPKFITLQLLFVWAVSFLLLLPPILGIWGEMGLDEATFSCTILKKEGRSIKKTLFVIGFLLPCLVIIVSYSCIYITVLHQKKKIRNHDNFQIAAAKGSSSSGGGSYMTTTCTRKAREDNRLTVMMVTIFLCFLVCFLPLMLANVVDDERNTSYP-----WLHIIASVMAWASSVINPIIYAASNRNYRVAYYKIFALLKFWGEPLSPMPSRNYHQSKNSKELSGVIRSTPLFHAVQKNSINQMCQTYSV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . . . . . .:..:**::.:::: :. .::: * . *::.*:.:**:. :. ** :: .* * *: .:: .* *::.:..*::* * *. * : : ::* :: : ::* : *.: * :***: :. . . .:. . *::* :: .* *:: *:: ::: . : . : * : *..:*: * :*: ** .:. :.: : . ", "identical_positions": 39, "similar_positions": 105, "identity": "9.7%" }, { "cls_id": "homologset.agr.RGD:620799", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHI8-1", "uniprot_id": "SEC20_RAT", "id": "Q8VHI8-1", "name": "Vesicle transport protein SEC20", "aln": "-------------------MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSELTELNTKVKEKFQQLK------------HRIQELEQSAKEQDKESEKQLLLQEVENHK---------------------------------KQMLSNQTSWRKANLTCKLAIDNLEKAELLQ--GGDSLRQRKTT-----KESLAQTSSTITESLMGISRMMSQQVQQSEEAMQTLVSSSRTLLDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6QD59-1", "uniprot_id": "SEC20_MOUSE", "id": "Q6QD59-1", "name": "Vesicle transport protein SEC20", "aln": "-------------------MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSELTELNTKVKEKFQQLK------------QRIQELEQSAREQDKESEKQLLLQEVENHK---------------------------------KQMLSNQTSWRKANLTCKLAIDNLEKAELLQ--GGDSLRQRKTT-----KESLAQTSSSITESLMGISRMMSQQVQQSEEAMQTLVSSSRTLLDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12981-4", "uniprot_id": "SEC20_HUMAN", "id": "Q12981-4", "name": "Vesicle transport protein SEC20", "aln": "-------------------MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLR------------HRIQDLEQLAKEQDKESEKQLLLQEVENHK---------------------------------KQMLSNQASWRKANLTCKIAIDNLEKAELLQ--GGDLLRQRKTT-----KESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VNI9-1", "uniprot_id": "Q9VNI9_DROME", "id": "Q9VNI9-1", "name": "", "aln": "--------------------MDKDAFTLQAIRQDLIDNNLQAKAIIHDILNSRTSIAELEELNEAGRSKLSAIR------------KSIERLDDWAR----DTADSALANEVDDHR---------------------------------DQFSKTLQAFRKANVSTMLEIEKANREELMAITGESELRQRTTTRARHNQGSLVSQENDVTEKMLAISRHLSETTQKSAITLETLVASSQNVEATSDELHHTAGSISMSGKLLKKYGRRECTDKMLLFFAFSLFLACVFYIVQKRLF---------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28791-1", "uniprot_id": "SEC20_YEAST", "id": "P28791-1", "name": "Protein transport protein SEC20", "aln": "MVVTFLQDLEVLQDALLNNLQKLSAISRRKESGESKHDNKDSFAAIANEHNDEEEEIEFEDLVNIIESKVSDFESVLKCSIVEMTYKYPELKLQWEKSPRYDQCDKLHIVKLDKQMNEDIYAQLVEELDFVLQFVDWFYCYRLKVKEILRQHHKRDLAWNDEKRDRAIKFHAVDYDKLHQGTSSSSSLTSTSMEKASTREKLLSKTKQLTNNLVRGNQILQSGILQSDLNLDELRAQTNSLTQIDDKYTQFETVFKKTADLVKVLENASHQEKRDVYLSLGFLLCCVSWVLWRRIFKLPVKLGLWLLFKFFKGILVTLGLVKSYAGSSSSLQAPSLVLNAPILATTTTSSATSVEPFASVSAVSSIQRAVDEAVDRIVSHDEL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . : : * * : : : :* ..*.. :. : : : : : .. :::.: * . ::.. : : :. : :* . . .: : .* . . :*:.:: .: : . :* :: * :.:..: .:: :. .*:. . . :* :::::.::*. * ::: :*:* ", "identical_positions": 16, "similar_positions": 91, "identity": "4.18%" }, { "cls_id": "homologset.agr.RGD:62080", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28648-1", "uniprot_id": "CD63_RAT", "id": "P28648-1", "name": "CD63 antigen", "aln": "-----MAVEGGMKCVKFLLYVLLLAFCACAVGLIAIGVAVQVVLKQAITHETTAGSLLPVVIIAVGAFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFSKSFQKQMQNYLTDNK--TATILDKLQKENKCCGASNYTDWERIPGM--------AKDRVPDSCCIN-------ITVGCGNDFKESTIHTQGCVETIAAWLRKNVLLVAGAALGIAFVEVLGIIFSCCLVKSIRSGYEVM-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41731-1", "uniprot_id": "CD63_MOUSE", "id": "P41731-1", "name": "CD63 antigen", "aln": "-----MAVEGGMKCVKFLLYVLLLAFCACAVGLIAIGVAVQVVLKQAITHETTAGSLLPVVIIAVGAFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNYLKDNK--TATILDKLQKENNCCGASNYTDWENIPGM--------AKDRVPDSCCIN-------ITVGCGNDFKESTIHTQGCVETIAIWLRKNILLVAAAALGIAFVEVLGIIFSCCLVKSIRSGYEVM-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08962-1", "uniprot_id": "CD63_HUMAN", "id": "P08962-1", "name": "CD63 antigen", "aln": "-----MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNH--TASILDRMQADFKCCGAANYTDWEKIPSM--------SKNRVPDSCCIN-------VTVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRSGYEVM-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLH1-1", "uniprot_id": "Q9VLH1_DROME", "id": "Q9VLH1-1", "name": "Tetraspanin", "aln": "----MSLLTGSANAVKYTLFGFNLIFLITGIILIAVGAGVGAVYTGYKLFLAGKFFSIPTFLIVIGSFIIIISFFGCWGALKENYCLVLSFSVMLAIIFILELAAGISGYVLRNDASDLIKTSLTYSLNEYNSINPNATTKLWDDIQDEFECCGVTSYNDWITAF----------PNGDLPISCCNVHVGAVGTFTCNNAQSSVADR-HKVGCLDGFSGYISAHAVSLGAAGVVIAILQFFGVIFACYIAREIKIRNGITGFM----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8K7-1", "uniprot_id": "A1Z8K7_DROME", "id": "A1Z8K7-1", "name": "Tetraspanin", "aln": "------MRSCGPSLIKYVLFAFNVLFAISGLGILIAGAVVLADVNEFNHFVEGRVLAPPIVLIVTGLIIFLIASLGCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQESIKRSNSED----TMAWDNIQQKLMCCGVDSPADWRTLS----------ANKTLPGSCCQPQYIDSTVGHCLESPALGKDKYFQVGCVGKLKDRIEKNAIILIGVGIGIAFIQILGIVLACYLANSIRQERAK--------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VID1-1", "uniprot_id": "Q9VID1_DROME", "id": "Q9VID1-1", "name": "Tetraspanin", "aln": "------MASGGLTCVKYLTFFCNLLFALTGLLIFLVGGMVQLNYAHYSNFVSDHVWTAPIILMIVGAAVAVICFLGCCGALKESSCMILSFALLAVVIFLFEIGLGLAGYVKHTGLHQIMESQFNSTMQHYKERAD--YRDAWTLLQTELDCCGINGPNDWETVY----------RNSTLPAACCS-------VINLSEAKECTNTHATQHGCLQKLLEILDSKTLILASVVLGVAGIQMLTILFACCLYRSFRRSYDHV-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLH0-1", "uniprot_id": "Q9VLH0_DROME", "id": "Q9VLH0-1", "name": "Tetraspanin", "aln": "MSNRELQLNSGMKCAKYMLIIVSFMFALTAILLIMVGTTIQTIFGDFSLFIDGHFSSPPALLIAIGFILIAVAALGAYGAVKESVMVINLYGVCLFLVFILEVSAAIAAFVMQSQVRGMLIRTMNQALAEYEHDPY--VESGVDFMQSMLECCGVNEPEDWKDYLSANVNFTLGVDDVVVPNSCCGNQ-----PTSLNDSTQMTCMETYDYGCFRKMNFIVSQSAMLIATGATTVAFVQLLGVLCAFMLAKTLRRNKSIREARRWQLQQSLGVLISGGKMAPPQNSAVTGYQQLDNGEQGSHEPYTYTPQSPSVN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *: . * .: :: * * .:: * : :. .*. ** **. :: :.: ::::.*:. .::. * : . : : . :* *** ** . :* :** . **. : : : : :* ::.: :: : : . :: ", "identical_positions": 24, "similar_positions": 60, "identity": "7.62%" }, { "cls_id": "homologset.agr.RGD:620800", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET45-1", "uniprot_id": "Q9ET45_RAT", "id": "Q9ET45-1", "name": "", "aln": "MSQSG-----EENLQGSWVELHFSN-GNGSSVPAS-----VSIYNGD-MEKILLDAQHESGRSSSK-SSHCDSPPRSQTPQDTNRA-EIDTHSFGEKNSTLSEEDYIERRREVESILKKNSDWIWDWSSRP-----ENVPPKEFLFKHPKRTATLSMRNTSVMKKGGIFSADFLKVFLPSLLLSHLLAIGLGIYIGRRLTTSTSTF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55003-1", "uniprot_id": "BNIP3_MOUSE", "id": "O55003-1", "name": "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3", "aln": "MSQSG-----EENLQGSWVELHFSN-GNGSSVPAS-----VSIYNGD-MEKILLDAQHESGRSSSK-SSHCDSPPRSQTPQDTNRA-EIDSHSFGEKNSTLSEEDYIERRREVESILKKNSDWIWDWSSRP-----ENIPPKEFLFKHPKRTATLSMRNTSVMKKGGIFSADFLKVFLPSLLLSHLLAIGLGIYIGRRLTTSTSTF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12983-1", "uniprot_id": "BNIP3_HUMAN", "id": "Q12983-1", "name": "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3", "aln": "MSQNGAPGMQEESLQGSWVELHFSNNGNGGSVPAS-----VSIYNGD-MEKILLDAQHESGRSSSK-SSHCDSPPRSQTPQDTNRASETDTHSIGEKNSSQSEEDDIERRKEVESILKKNSDWIWDWSSRP-----ENIPPKEFLFKHPKRTATLSMRNTSVMKKGGIFSAEFLKVFLPSLLLSHLLAIGLGIYIGRRLTTSTSTF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKA1-1", "uniprot_id": "A0A8M2BKA1_DANRE", "id": "A0A8M2BKA1-1", "name": "", "aln": "MSIEKHS-VSEENLQGSWVELHFNNGGGSTSKAATDEQSASTAPSGD-LEKMLLDAQHESGRSSSRGSLPCDSPPRSQTPLHLCRG--SEVHSSGEKNSSQSEEDYLERRKEVEILMKKNADWIWDWSSRP-----ENLPPKEFLLRHPKRSSTLSMRNTSVMKKGGIFSAEFLKVFLPSLVLSHILAVGLGVYIGRRFTASG-TF--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPD6-1", "uniprot_id": "Q9VPD6_DROME", "id": "Q9VPD6-1", "name": "", "aln": "MSTTPKS--SEDLLGESWIELSTTAAMAGIKSPDR--ITPLPFNNGEEYLRLLREAQRESNQSSRVVSLASS---RRDTPRDSPKSPPNSPQSELCPDDELRNVYINYWTKGGDKQNAGNEDWLKNWNQPPSSWNIEDSSRDAGDEGEKKKTNTGYSIRLKRLGSNSLFSREILYSLLVTNVLSLLLGAGFGLWLSKRGILLTRVVID", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *: * **:** . . . . . .*: ::* :**:**.:** * .. * :** . :. . :* :. : : : * **: :*.. * *: . . . *:: * . . : ...:** ::* :* : :** :*. *:*:::.:* .. ", "identical_positions": 39, "similar_positions": 60, "identity": "18.75%" }, { "cls_id": "homologset.agr.RGD:620801", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97586-1", "uniprot_id": "CGRE1_RAT", "id": "P97586-1", "name": "Cell growth regulator with EF hand domain protein 1", "aln": "MSRWLMQMLMLPLLLLPLGQAAPKDGVARLDPEAQQQLTTNPFQPGPEQLRRLRDYLKGLEKMEEDPEQMNREQVLLYLFALHDFDQNGQLDGLELLSMLTAALAPGAAHFP-INPVILVVDMVLETQDLDGDGLMTPAELINFPGEAPKRAES---LPPALQEPQPAGSQPLLANSPLQSETQQSLGTKEEITSQVEAKRA-LEPEQE----------------------------------AGHHIETKVDALSPEGEARGQAESEGDAPGPREDAERQVESKDNEGEAKDLPAETLETQNTPNVVEAHSIQLENDEI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1U2-1", "uniprot_id": "CGRE1_MOUSE", "id": "Q8R1U2-1", "name": "Cell growth regulator with EF hand domain protein 1", "aln": "MFQWLMQALMLPLLLLPLGRAAPKDGVARLDPEVQQQLTPNPFQPGPEQLRHLQNYLKGLEKMEEDPEHMDREQVLLSLFALHDYDQNGQLDGLELLSMLTAALAPGAAHFP-INPVILVVDSVLETQDLDGDGLMTPAELINFP-EVPKHTES---LPPALQEPQPAGSQPLLANSPLQSETQQSLGTKEEIRGQVEAKRASLEPEQE----------------------------------AGHQTEGKVDTLSPEEEARGQAESEGDVPGPREGAEEQVEIKDNEGEAKELLVETLESLNTPNEAEAHSIQLENDEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99674-4", "uniprot_id": "CGRE1_HUMAN", "id": "Q99674-4", "name": "Cell growth regulator with EF hand domain protein 1", "aln": "MLPLTMTVLIL--LLLPTGQAAPKDGVTRPDSEVQHQLLPNPFQPGQEQLGLLQSYLKGLGRTEVQLEHLSREQVLLYLFALHDYDQSGQLDGLELLSMLTAALAPGAANSPTTNPVILIVDKVLETQDLNGDGLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQNDFEVHIVQVENDEI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *:* **** *:*******:* *.*.*:** .****** *** *:.***** : * : *::.****** ******:**.*********************: * *****:** *******:************** . ::.*. *.*: ****..* *.***:***:.***:: *.:** .****:* *:* ** ** : * : *: .*. ** ****:***.**** * *.* ::* ***:* ****: ** * *.* :*:*****", "identical_positions": 174, "similar_positions": 54, "identity": "54.38%" }, { "cls_id": "homologset.agr.RGD:620802", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54957-1", "uniprot_id": "LAT_MOUSE", "id": "O54957-1", "name": "Linker for activation of T-cells family member 1", "aln": "MEADALSPVGLGLLLLPFLVTLLAALCVRCRELPVSYDSTSTESLYPRSILIKPPQITVPRTPAVSYPLVTSFPPLRQPDLLPIPRSPQPLGGSHRMPSSQQNSDDANSVASYENQ---------------------------EPACKNVDADEDEDDYPN-GYLVVLPDSSPAAVPVVSSAPVPSNPDLGDSAFSVESCEDYVNVPESEESAEASLDGSREYVNVSPEQQP-VTRAELASVNSQEVEDEGEEEGVDGEEAPDYENLQELN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70601-1", "uniprot_id": "LAT_RAT", "id": "O70601-1", "name": "Linker for activation of T-cells family member 1", "aln": "MEADALSPVELGLLLLPFVVMLLAALCVRCRELPASYDSASTESLYPRSILIKPPQITVPRTPATSYPLVTSFPPLRQPDLLPIPRSPQPLGGSHRMPSSRQNSDDANSVASYENQ---------------------------EPARKNVDEDEDEDDYPE-GYLVVLPDSSPAAVPVVSSAPVPSNPDLGDSAFSMESCEDYVNVPESEESAEASLDGSREYVNVSQDAQP-VIRAELASVTSQEVEDE-EEEDVDGEEAPDYENLQELN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43561-1", "uniprot_id": "LAT_HUMAN", "id": "O43561-1", "name": "Linker for activation of T-cells family member 1", "aln": "MEEAILVPCVLGLLLLPILAMLMA-LCVHCHRLPGSYDSTSSDSLYPRGIQFKRPHTVAPWPPA--YPPVTSYPPLSQPDLLPIPRSPQPLGGSHRTPSSRRDSDGANSVASYENEGASGIRGAQAGWGVWGPSWTRLTPVSLPPEPACEDADEDEDDYHNPGYLVVLPDSTPATSTAAPSAPALSTPGIRDSAFSMESIDDYVNVPESGESAEASLDGSREYVNVSQELHPGAAKTEPAALSSQ------EAEEVEEEGAPDYENLQELN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * * *******::. *:* ***:*:.** ****:*::*****.* :* *: ..* .** ** ***:*** ******************* ***:::**.*********: * * ******* : *********:**: ....***. *.*.: *****:** :******** ***************** : :* . ::* *::.** * * *: * ***********", "identical_positions": 153, "similar_positions": 44, "identity": "56.46%" }, { "cls_id": "homologset.agr.RGD:620803", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97587-1", "uniprot_id": "CGRF1_RAT", "id": "P97587-1", "name": "Cell growth regulator with RING finger domain protein 1", "aln": "MAAVFLVTLYEYSPLFYIAVVFTCFIATTGLVLGWLGWDVPVILRNSEETQFSTRAFKKQMRQVKNPFGLEITNSSAASLATGVTLTTDCLEDSRLTCYWGCSVQKLYEALQKHVYCFRISTPQALEEALYSDYLHREQYFIKKHSKEEIYCQLPSSTGVEDFGPVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDKTYKLPCRILYQYLILAQGQFYDLKQLFMSANNSATPSRDQSPADGSVEHSLLEKAGLAGAEVDPVEESSKDCVVCQNGGVNWVLLPCRHACLCDSCVCYFKQCPMCRQFVQESFALCGQKEADKDILETS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMJ7-1", "uniprot_id": "CGRF1_MOUSE", "id": "Q8BMJ7-1", "name": "Cell growth regulator with RING finger domain protein 1", "aln": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEETQFSTRAFKKQMRQVKNPFGLEITNSSAASLATGMALRTDCLEDSRLTCYWGCSVQKLYEALQKHAYCFRISTPQALEEALYSDYLHREQYFIKKHSKEEIYCQLPSDTEIEDFGPVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDKTYKLPCRILYQYLILAQGQFYDLKQLFMSANNSPPPSNDESPEDRSVEQSLLEKVGLAGNDGDPVEESSRDCVVCQNGGVNWVLLPCRHACLCDSCVRYFKQCPMCRQFVQESFALCGQKEPDKDLLETS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99675-1", "uniprot_id": "CGRF1_HUMAN", "id": "Q99675-1", "name": "Cell growth regulator with RING finger domain protein 1", "aln": "MAAVFLVTLYEYSPLFYIAVVFTCFIVTTGLVLGWFGWDVPVILRNSEETQFSTRVFKKQMRQVKNPFGLEITNPSSASITTGITLTTDCLEDSLLTCYWGCSVQKLYEALQKHVYCFRISTPQALEDALYSEYLYQEQYFIKKDSKEEIYCQLPRDTKIEDFGTVPRSRYPLVALLTLADEDDREIYDIISMVSVIHIPDRTYKLSCRILYQYLLLAQGQFHDLKQLFMSANNNFTPSNNSSSEEKNTDRSLLEKVGLSESEVEPSEENSKDCVVCQNGTVNWVLLPCRHTCLCDGCVKYFQQCPMCRQFVQESFALCSQKEQDKDKPKTL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************************.********:*******************.******************.*:**::**::* ******* *******************.************:****:**::*******.********** .* :****.************************************:****.********:******:***********. .**.:.*. : ..::*****.**: : :* **.*:******** **********:****.** **:****************.*** *** :* ", "identical_positions": 271, "similar_positions": 44, "identity": "81.63%" }, { "cls_id": "homologset.agr.RGD:620804", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38656-1", "uniprot_id": "LA_RAT", "id": "P38656-1", "name": "Lupus La protein homolog", "aln": "---------------------------------------------------------------------------------MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKANLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLD--------DIKEWLDDKGQILNIQMRRTLHK-----TFKGSIFAVFDSIQSAKKFVDTPGQK-YKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGS-TETRALEGKMGCLLKFSGDLDDQTCREDFHFLFSNHG--EIKWIDFVRGAKEGIILFKEKAKDALEKARSANNG-NLLLRNKKVTWKVLEGHAEKDAMKKITDDQQESLNKWKSKGGHAARRFKGSHVFTAARRFKGRGKGNRPAYAGAPKGRGQFQGRRTRFDDDDHR--------RGPVKRGIDGRDREEPASKHKKRENGARDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32067-1", "uniprot_id": "LA_MOUSE", "id": "P32067-1", "name": "Lupus La protein homolog", "aln": "---------------------------------------------------------------------------------MAENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLD--------DIKEWLDDKGQILNIQMRRTLHK-----TFKGSIFAVFDSIQSAKKFVEIPGQK-YKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGS-TETRALEGKMGCLLKFSGDLDDQTCREDLHFLFSNHG--EIKWVDFARGAKEGIILFKEKAKEALEKARNANNG-NLLLRNKKVTWKVLEGHAEKEALKKITDDQQESLNKWKSKGGHAGGRFKGSHVFTAARRFKGKGKGNRPGYAGAPKGRGQFHGRRTRFDDDDRR--------RGPMKRGRDGRDREEPASKHKKRENGARDK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05455-1", "uniprot_id": "LA_HUMAN", "id": "P05455-1", "name": "Lupus La protein", "aln": "---------------------------------------------------------------------------------MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLD-EGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLD--------DIKEWLEDKGQVLNIQMRRTLHK-----AFKGSIFVVFDSIESAKKFVETPGQK-YKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHG--EIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNG-NLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKG----------------RRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JQB7-1", "uniprot_id": "A0AC58JQB7_DANRE", "id": "A0AC58JQB7-1", "name": "", "aln": "MQLHEARSPKPELVPVNVYDRSCVLCTICTQAMHMFSVLLKRNKITTELWPVSCCLTGGVIGVDGYTVIQRSTNEVMFVVILAKMADNQEMSPLEKKVAEQIEYYFGDHNLPRDKFLKEQLQLD-DGWVPLETMLKFNRLKSLTSEESVIVESLLKSKTGLLEISEDKTKIRRDPNKPLPENNEEYRDALKHKSIYMKGFPLETTLD--------DVKEWLADKGTFENIYLRKGPQK-----TFKGSIFAVLETEEAAKAFVERDDIKNFKGNEMIVMMKDAYFTKKIAERKQNRVESKAKAKCDKEEKQKQAEEEEMKSLNEQRGCLLKFSGELG-QTSREDFHSVFSDHA--QIKWIDFTRGAKEGTILFHSNAKEALQKVREALNGEDPKVKEQAVQWEILEGDVEMETLKKIIEDQQESINKRKGGRG----------------GFRGRGRGRGGRRDRGGREHTQFKGKKTKFDSDEEGDEESASTKKRPLESNRQ--DNGEPVSKQAKSENGS---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40796-1", "uniprot_id": "LA_DROME", "id": "P40796-1", "name": "La protein homolog", "aln": "--------------------------------------------MAEVAETPSVEAQEEVAQPAEAQVLEAKNGDAKKDPAPAAEEAAGGFTKQERAIIRQVEYYFGDANLNRDKFLREQIGKNEDGWVPLSVLVTFKRLASLSTDLSEIVAALNKSEEGLVEISEDKLSLRRHPERPIPEHNEERRKEIQERTAYAKGFPLDSQIS--------ELLDFAANYDKVVNLTMRKHYDKPTKSYKFKGSIFLTFETKDQAKAFLEQEKIV-YKERELLRKWQVDYLKEKQEEYAQKNEKRKNKKEAKPEP-----------AFELPKNAIVVFEGAPE-TSSREEIREAFEKIKDFEVAYIEFAKGETKGSVRLTEADAAEKYIAKVEEGK-LKFKDEVSLSLRKATEEEEKEFIDKAIEFMKKRRDFTRNKGK----------------RFNRKRHGGNDHKHGG--------GKKARGD-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33399-1", "uniprot_id": "LHP1_YEAST", "id": "P33399-1", "name": "La protein homolog", "aln": "-----------------------------------------------------------------MSEKPQQEEQEKPQSRRNSFAVIEFTPEVLDRCLKQVEFYFSEFNFPYDRFLRTTAEKN-DGWVPISTIATFNRMKKYRP-VDKVIEALRSSE--ILEVSADGENVKRRVPLDLTAARN-ARIEQNQRTLAVMNFPHEDVEASQIPELQENLEAFFKKLGEINQVRLRRDHRNK----KFNGTVLVEFKTIPECEAFLKSYSND-DESNEILSYEGKKLSVLTKKQFDLQREASKSKN----------------------------FSGRSR-----------------------SFNGHKKKNLPKFPKNKKKNGK-------------------------EESKEDSSAIADDDEEHKE-------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .*:*:**.: *: *:**: : :****:. : .*:*: . . :: :* .*: ::*:* * .::* :. : : :.:: .** : :: : . . . :: :*: : *:*::: :.: .: *:. : ::: . : .. * : *.* .* .:. : . . . : . : :: : ", "identical_positions": 30, "similar_positions": 86, "identity": "5.74%" }, { "cls_id": "homologset.agr.RGD:620805", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8K2-1", "uniprot_id": "G3V8K2_RAT", "id": "G3V8K2-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPTSE-NPFREKKFFCALL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63216-1", "uniprot_id": "GBG3_MOUSE", "id": "P63216-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3", "aln": "MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPTSE-NPFREKKFFCALL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63215-1", "uniprot_id": "GBG3_HUMAN", "id": "P63215-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3", "aln": "MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPTSE-NPFREKKFFCALL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38040-1", "uniprot_id": "GBG1_DROME", "id": "P38040-1", "name": "Guanine nucleotide-binding protein subunit gamma-1", "aln": "----MDVMSS-SLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSS-CTVL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: *: * * :****: **:: * .:*::.*.:*.* * ** *:* ..:.: ******. *::*", "identical_positions": 29, "similar_positions": 23, "identity": "38.16%" }, { "cls_id": "homologset.agr.RGD:620806", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AF64-1", "uniprot_id": "A0A8I6AF64_RAT", "id": "A0A8I6AF64-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "GAVSVAQRQGLGVTALHPVGPLRRPGAPLAGGFAVAWAPRCFPLSPQTRRSSVARDPASGDTGRAFTEPGARDAAWPGRPRRAPRRGPSPRLSGTGCAPAAGAPQQDPESASLLTAKFCCCSVPCLDLSLYHLSAGSAGMKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAASDLLAYCEAHVREDPLIIPVPASE-NPFREKKFFCTIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50153-1", "uniprot_id": "GBG4_MOUSE", "id": "P50153-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAASDLLAYCEAHVREDPLIIPVPASE-NPFREKKFFCTIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50150-1", "uniprot_id": "GBG4_HUMAN", "id": "P50150-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASE-NPFREKKFFCTIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38040-1", "uniprot_id": "GBG1_DROME", "id": "P38040-1", "name": "Guanine nucleotide-binding protein subunit gamma-1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MDVMSSSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREK-SSCTVL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::*:.* * .****: **.:** .:*::.:.:: * * :** *: ..:.: ****** **:*", "identical_positions": 26, "similar_positions": 26, "identity": "12.09%" }, { "cls_id": "homologset.agr.RGD:620807", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63218-1", "uniprot_id": "GBG5_HUMAN", "id": "P63218-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "aln": "MS-GSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSS-TNPFRPQKVCSFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80SZ7-1", "uniprot_id": "GBG5_MOUSE", "id": "Q80SZ7-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "aln": "MS-GSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSS-TNPFRPQKVCSFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63219-1", "uniprot_id": "GBG5_RAT", "id": "P63219-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "aln": "MS-GSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSS-TNPFRPQKVCSFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38040-1", "uniprot_id": "GBG1_DROME", "id": "P38040-1", "name": "Guanine nucleotide-binding protein subunit gamma-1", "aln": "MDVMSSSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSSCTVL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ***: : **:*** **.::* .:*::.*.: :: :: *.* ****.:*. .**** :. *:.*", "identical_positions": 27, "similar_positions": 27, "identity": "38.57%" }, { "cls_id": "homologset.agr.RGD:620808", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63077-1", "uniprot_id": "GBG8_RAT", "id": "P63077-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8", "aln": "MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVP-AAENPFRDKRLFCTLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63078-1", "uniprot_id": "GBG8_MOUSE", "id": "P63078-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8", "aln": "MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVP-AAENPFRDKRLFCTLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK08-1", "uniprot_id": "GBG8_HUMAN", "id": "Q9UK08-1", "name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8", "aln": "MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVP-AAENPFRDKRLFCVLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38040-1", "uniprot_id": "GBG1_DROME", "id": "P38040-1", "name": "Guanine nucleotide-binding protein subunit gamma-1", "aln": "MDVMSSSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREK-SSCTVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4K838-1", "uniprot_id": "A0A0B4K838_DROME", "id": "A0A0B4K838-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "---MAANLQQQRSINLQLRREVEMERMPVSVACSLMMKYMLEHEEEDCLLSGFT-QKVNPFREK-SSCSIL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: : * **: *. ::* :* :.: :: : * ::* *:: .. ****:* * :*", "identical_positions": 16, "similar_positions": 23, "identity": "22.54%" }, { "cls_id": "homologset.agr.RGD:620809", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTX9-1", "uniprot_id": "E9PTX9_RAT", "id": "E9PTX9-1", "name": "", "aln": "MEPGPAAPSSG-APRPARDG---DAPLTAAGVDLPGTAVLSGREDAT-AGSQAGGGVRGEGTPAAGDGLGKPLGPTPSQ--SRFQVDPVSENAGRAA----------AAAAAAAAAAAAG---AAGKETPAAGKAGTESGVAKGSEEAKGRFRVNFVDPAASSSADDSLSDAAGVGGDGPNVSFQNGGDTVLSEGSSLHSGGG--SGHHQQYYYDTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKEPFEDGFANGEESTPTRDAVVTYTAESKGVVKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIAMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMID-EINDIRIIGAITVVVLLGISVAGMEWEAKAQIVLLVILLLAIADFVIGTFISLD---SKKPKGFFGYKSEIFSENFGPDFR-----EEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTVVYIGIAVSVGSCVVRDATGNVNDTITTELTNCTSAACKLNFDFSYC------ESNTCSYGLMNNFQVMSMVSGFAPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLTGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLSALQHSIRLSGVEDHVKNFRPQCLVMTGSPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEGLDISHLQ----------------------GQEELLSSQEKSPGTKDVVVNVDYSK----------KSDQD-----------------------------AFKASG------EKPITQKDEEEDGKTSTQPLLKKESKGPVAPLN-----VADQKLLEASTQFQKKQGKNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGG-KINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKENIVAFDDMIEPYRLHEDDKEQDIADKMK-EDEPWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLP-PILLVRGNHQSVLTFYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55012-1", "uniprot_id": "S12A2_MOUSE", "id": "P55012-1", "name": "Solute carrier family 12 member 2", "aln": "MEPGPARPRLAPAARPGWGR---AAGCRRRGGPAR-HGRASGQEDATTAGRQAGGGVRGEGTPAAGDGLGRPLGPTPSQ--SRFQVDPVSENAGRAA----------AAAAAAAAAAAAAG--AAGKETPAAGKAGGESGVAKGSEEAKGRFRVNFVDPAASSSADDSLSDAAGVGGDGPNVSFQNGGDTVLSEGSSLHSGGG--SGHHQQYYYDTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKEPFEDGFANGEESTPTRDAVVAYTAESKGVVKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVVVIAMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMID-EINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIADFVIGTFISLE---SKKPKGFFGYKSEIFNENFGPDFR-----EEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTVVYIGIAVSVGSCVVRDATGNVNDTITTELTNCTSAACKLNFDFSYC------ESNTCSYGLMNNFQVMSMVSGFAPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLIGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLSALQHSIRLSGVEDHVKNFRPQCLVMTGSPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQARYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQFGVVVIRLKEGLDISHLQ----------------------GQEELLSSQEKSPGTKDVVVNVDYSK----------KSDQD-----------------------------TCKSSG------EKSITQKDEEEDGKTPTQPLLKKESKGPIVPLN-----VADQKLLEASTQFQKKQGKNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGG-KINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKENIIAFDDMIEPYRLHEDDKEQDIADKMK-EDEPWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLP-PVLLVRGNHQSVLTFYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55011-1", "uniprot_id": "S12A2_HUMAN", "id": "P55011-1", "name": "Solute carrier family 12 member 2", "aln": "MEPRPTAPSSGAPGLAGVGETPSAAALAAARVELPGTAVPSVPEDAAPASRD-GGGVRDEGPAAAGDGLGRPLGPTPSQ--SRFQVDLVSENAGRAA----------AAAAAAAAAAAAAGAGAGAKQTPADGEASGESEPAKGSEEAKGRFRVNFVDPAASSSAEDSLSDAAGVGVDGPNVSFQNGGDTVLSEGSSLHSGGGGGSGHHQHYYYDTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKEPFEDGFANGEESTPTRDAVVTYTAESKGVVKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMID-EINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLE---SKKPKGFFGYKSEIFNENFGPDFR-----EEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTELTNCTSAACKLNFDFSSC------ESSPCSYGLMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLNALQHSIRLSGVEDHVKNFRPQCLVMTGAPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEGLDISHLQ----------------------GQEELLSSQEKSPGTKDVVVSVEYSK----------KSDLD-----------------------------TSKPLS------EKPITHKVEEEDGKTATQPLLKKESKGPIVPLN-----VADQKLLEASTQFQKKQGKNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGG-KINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKENIIAFEEIIEPYRLHEDDKEQDIADKMK-EDEPWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLP-PILLVRGNHQSVLTFYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2KTI4-1", "uniprot_id": "S12A2_DANRE", "id": "A0A0G2KTI4-1", "name": "Solute carrier family 12 member 2", "aln": "MSASPPISAGDYLSAP------------------------------------------------EPDAL-KPAGPTPSQ--SRFQVDLVTESAGDGE----------TTVGFDSSPPEYVA------EPPPDGLRDSVS----GGEEAKGRFRV--VNFAASS------PDAA------PAETAQNG-DTVMSEGSLHSSTGG-----QQHHHYDTHTNTYYLRTFGHNTIDAVPKIDFYRQTAAPLGEKLIRPTLSELHDELDKEPFEDGFANGEELTPAEESAAKDVSESKGVVKFGWIKGVLVRCMLNIWGVMLFIRMTWIVGQAGIAYSCIIVIMATVVTTITGCSTSAIATNGFVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVELLMDSGLLMID-QTNDIRVIGTITVILLLGISVAGMEWEAKAQIFLLVILITAIFNYFIGSFIAVD---SKKKFGFFSYDAGILAENFGPDFR-----G-QTFFSVFSIFFPAATGILAGANISGDLADPQMAIPKGTLLAILITGLVYVGVAISAGACIVRDATG--IESNFTLISNCTDAACKYGYDFSSCRPTVEGEVSSCKFGLHNDFQVMSVVSGFSPLISAGIFSATLSSALASLVSAPKVFQALCKDNIYPGIAIFGKGYGKNNEPLRGYFLTFGIALAFILIAELNVIAPIISNFFLASYALINFSVFHASLANSPGWRPSFKYYNMWASLAGAILCCVVMFIINWWAALLTNVIVLSLYIYVSYKKPDVNWGSSTQALTYHQALTHSLQLCGVADHIKTFRPQCLVMTGAPNSRPAILHLVHAFTKNVGLMLCGHVRISSRRPNFKELNSDMLRYQRWLLNNNSKAFYTCVVAEDLRQGTQYMLQAAGLGRLRPNTLVIGFKNDWRTGDIKEVETYINLIHDAFDFQYGVVILRLREGLDISHIQ----------------------GQD-------DSSGMKDVVVSVDISK----------DSDGD-----------------------------SSKPSSKATSVQNSPAVQKDEDDDGKAHTQPLLKKDKKSPTVPLN-----VADQRLLDASQQFQQKQGKGTVDVWWLFDDGGLTLLIPYLIANKKKWKDCKIRVFIGG-KINRIDHDRRAMATLLSKFRIDFSDITVLGDINTKPKSEGLTEFAEMIEPYKLREDDMEQEAAEKLK-SEEPWRITDNELELYKAKGNRQIRLNELLKEHSSTANLIVMSMPLARKGAVSSALYMAWLDTLSKDLP-PILLVRGNHQSVLTFYS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PI37-1", "uniprot_id": "M9PI37_DROME", "id": "M9PI37-1", "name": "", "aln": "----------------------------------------------------------------MSDTISFELGSAADRPPNRFQVNPVNGNSRKSQGADGPGSGSGAGAGAGAGAGEDGPHEVYRRLTNAEGELLEDDTFDATQMLNQRQPRQQRQSIKSSFRDKDK-----------PSRFKDLQTTTRFQVDPQNEESDESNDSQEERELLDNEYDTKYGKSFRHFTREALPRLDNYRNMMSIQAAY--RPTLDELHNAT---------LVGKNTHSLTRNQDPESGILNGVLKFGWIKGVLVRCLLNIWGVMLFLRLSWVVGQAGVIEGFVLILTTTAVTTITALSMSAISTNGVIKGGGTYYMISRSLGPEFGGSIGLIFSLANAVACAMYVVGFCESMLAMMTTFGWEIIDGGVQDVRIIGCITILLLLIIVVVGMEWEAKAQIGLLIILLVAIGDFVIGSFIGPK-SDAEMAKGFLGYNATLFKNNLFADYRPEKGGIQHDFFSVFAIFFPAATGILAGANISGDLKDPQKSIPKGTILAIVITTGTYLIMVLQCGATVARDATGNLSDVVNGTFAF---LDCQP---------------GECNYGLQNSFQVIELVSAFGPLIYAGCYAATLSSALASLVSAPKVFQALCKDELYPKIVWFAKGYGKNNEPVRGYVLTFIIACAFILIGELNLIAPLISNFFLAAYMLINFSTFHASLAKPVGWRPTFKYYNMWLSLLGAILCVAVMFLISWATALITFAAVLALYLIVAYRKPDVNWGSTTQAQTYKNALMSVQQLNNVEEHVKNYRPQILVLSGLPNTRPVLVDLAYMLTKNLSLLVCGHVLKG--SSSQKYRTYLQERAGNWFRKHRVKGFYALVDGEDFESGTRALMQATGIGKLKPNIILMGYKTDWQTCDHKELDQYFNVMHKALDMYLSVAILRVPQGLDCSQVLGSQDGWKTVSDVPRTLQPNESSGDLQAVDSSVRNGLSGSIDSLSRNVSQEDRNRNQLVHSEQNSLKIVKLRFKQGLRRMRSWPGAASSTSDLSFIAGNQSKDVSGMPDPLDAKSANLVSNSLRKSKLKHDDPASLYKGPGGAELPKEVLADLTQFTRKRSHAVIDVWWLYDDGGLTLLLPYIISTRRTWQSCKLRVYALANKNSELEFEQRSMASLLSKFRIDYSDLTLIPDITKKPQETSTQFFNELIKDFVVTEKDGENGTSSRATLNEDDALITDDDLLAVQDKTNRYLRLREYLREQSTKSDLVVMTLPMPRKNIVSAPLYMAWLESLSRDMP-PFLFVRGNQTSVLTFYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNC7-1", "uniprot_id": "Q9VNC7_DROME", "id": "Q9VNC7-1", "name": "", "aln": "---------------------------------------------------------------------------MADR----FQISKVNGTAN-------------AGYDGEARSAESD-------QTDAAHPLPPTSNENHLHPKASGETGENRRSSRLSFRG-----------------FGNFLRKS----------------------------DAERKFSLAQLTKESLPRLDNYR--ISMRNLK--RPSIGELQ--------------GEAVDQSITIPEPEPEATGGHIKLGWIVGVLIPCLLNIWGVMLFLRLSWVVAESGILQSLIIITISAVVCVITTLSLSAISTNGEVKGGGVYFIISRSLGPEFGASVGVVFAFANAVSASMNTIGFCESLNVLLKNNDLKIVDNGINDIRIVGSITVLVLILICCVGMEWETKAQNFLIVTIVLAIFNFLIGAAIGPQGNEEQISRGFVGFSWATLKENFGSDYRYAEG-VNHDFFSVFAIFFPSVTGIQAGANICGDLKDAGAAIPKGTFWSLLISMSSYALFVLFAGGAAVRDASGIPADLVNGTIVSSE-LPCMAT--------------GNCTWGLFNSYEMMQEMSLWGPLIYAGCFAATLSTALTNLLSVPRLVQALGIDQIYPGLIFFSKPYGKHGEPYRGYVLTFFITTGFLLIGELNLIAPLISTFYLASYALINFCTFHAAFVKPLGWRPTFKYYNAWLSLFGFAMCVAIMFLINYVAAIITFGIIFALYLVVMYRKPEANWGSTTQAQQYKAALMAVHRLQNVSDHVKNYHPQVLVLSGDPKTRPPLVDFGYLLTKNNSLMFVANIIPV--RVGYKNRQHLVKDGQKYLDARKIKAFYNVIDGFSLEDGINALTKSTGFGKMSPNIVLVGYKPDWNRCRKEEVESYFSILYNAFSQRMGVALLRLPNGLDFSELS---------SEVT---LPANGMGHMHTAN---AHGFTNELMPAANAAS-------ELLHIDSN----------------------------LNLASMDSPNSSFTMPQP--APMPNMQRNSRSYKVTSSDEPAVTYHTKGGSDIPQNLLDAMTIFTRKQPKGTIDVFWLYDDGGLTILLPYIISMRSHWQNSKLRVFAMCHGKDE-EQEEKSMASLLTKFRIKYSELIMLKGVSEQPRADTVLKHKRLIEPFRRGARN-EFG-------------ITDDELQSMSEKTNRQLRIHELVVKHSSNASLVVMSLPMPRKEAISAPLYMSWLEMLTSDMKCPVALARGNQTPVLTLYS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: **:. *. .: : : . . . . . . . * : : :: :: : * :::*::* ** : **:: **: *: * :*:*** ***: *:*********:*::*:*.::*: . ::: ::.* .** * ***:*** ::***.*::**********.::*::*::****: :* .:**.*:: :: . ::* :*:*::* **:::*: * .*****:*** *:: :: ** ::.**: * . : **..:. : :*: .*:* . *****:****:.*** *****.*** *. :*****: :::*: * ..: *. .***:* : : * . *.:** *.::::. :* : *** ** ::****:**:.*:*.*::.*** *::** : *.* ***:.** ***.*** *: .*:**.***:***:**.*:**:* ****..***::.:. ****:***** * ** * :* :**:*.: :*::* ::.**: * *:**:.****:*** * ** :* .* :*:*.::** **::* *::** ::.: : :*** .*:. .:: * .:: .. *.** : . .:..* . : :::*:*:: ** :::*:* ** .::: *:.:::.*:. .*.::*: :*** *.: *. .: . . : : . . . : : . . * : :.:* * :*: : .:**:**:******:*:**::: : *:..*:**: .. : :.::**:**:****.:*:: :: .:. :*: . :*: : : * ***::* . * * :*:.* : ::*:.:.::**::*:.** :*:.***:**: *: *: *. :.***: .***:**", "identical_positions": 329, "similar_positions": 349, "identity": "25.02%" }, { "cls_id": "homologset.agr.RGD:62081", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14469-1", "uniprot_id": "HES1_HUMAN", "id": "Q14469-1", "name": "Transcription factor HES-1", "aln": "--MPADIMEKN--SSSPVAATPASVNTTPDKPK--TASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL---ANCMTQINAMT-----YPGQPHPALQAPPPPPP-GPGGPQ-------HAPFAPPPP------------------LVPIPGGAAPPPG--GAP-CKLGSQAGEAAKVFGGFQ-----------------------VVPA--PD-------GQFAFLIPN-----------------------------------GAFAHSGPVIPVYTSNSGTSVGPNAVS------------------------------------------PSS-----GPSLTADSMWRPWRN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04666-1", "uniprot_id": "HES1_RAT", "id": "Q04666-1", "name": "Transcription factor HES-1", "aln": "--MPADIMEKN--SSSPVAATPASVNTTPDKPK--TASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL---ANCMTQINAMT-----YPGQAHPALQAPPPPPPSGPGGPQ-------HAPFAPPPP------------------LVPIPGGAAPPPG--SAP-CKLGSQAGEAAKVFGGFQ-----------------------VVPA--PD-------GQFAFLIPN-----------------------------------GAFAHSGPVIPVYTSNSGTSVGPNAVS------------------------------------------PSS-----GSSLTADSMWRPWRN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35428-1", "uniprot_id": "HES1_MOUSE", "id": "P35428-1", "name": "Transcription factor HES-1", "aln": "--MPADIMEKN--SSSPVAATPASVNTTPDKPK--TASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL---ANCMTQINAMT-----YPGQAHPALQAPPPPPPSGPAGPQ-------HAPFAPPPPP-----------------LVPIPGGAAPPPG--SAP-CKLGSQAGEAAKVFGGFQ-----------------------VVPA--PD-------GQFAFLIPN-----------------------------------GAFAHSGPVIPVYTSNSGTSVGPNAVS------------------------------------------PSS-----GSSLTSDSMWRPWRN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q26263-1", "uniprot_id": "DPN_DROME", "id": "Q26263-1", "name": "Protein deadpan", "aln": "MDYKNDINSDDDFDCSNGYSDSYGSNGRMSNPNGLSKAELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARHTKLEKADILEMTVKHLQSVQRQQLNMAIQSDPSVVQKFKTGFVECAEEVNRYVSQMDGIDTGVRQRLSAHLNQCANSLEQIGSMSNFSNGYRGGLFPATAVTAAPTPLFPSLPQDLNNNSRTESSAPAIQMGGLQLIPSRLPSGEFALIMPNTGSAAPPPGPFAWPGSAAGVAAGTASAALASIANPTHLNDYTQSFRMSAFSKPVNTSVPANLPENLIHTLPGQTQLPVKNSTSPPLSPISSISSHCEESRAASPTVDVMSKHSFAGVFSTPPPTSAETSFNTSGSLNLSAGSHDSSGCSRPLAHLQQQQVSSTSGIAKRDREAEAESSDCSLDEPSSKKFLAGAIEKSSSAWRPW--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ..: ..* : . . * .:*: : :* **:.*************..*.:**:***:*:***.:**:***************:.:** *:. *:.:****: *:::** ** :**.*::* :*::* ** ** .** **.: **.:*: * * .** ....*.* *. ** . **. ::* .*.****** . * . * ** *: .:..: *** *: ** : : * *.*: . *. . : *:. *:. .* * *** *. .:.* **** ", "identical_positions": 125, "similar_positions": 89, "identity": "28.6%" }, { "cls_id": "homologset.agr.RGD:620810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PI8-1", "uniprot_id": "RTN4R_MOUSE", "id": "Q99PI8-1", "name": "Reticulon-4 receptor", "aln": "MKRASSGGSRLLAWVLWLQAWRVATPCPGACVCYNEPKVTTSCPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCNLPQRLADRDLKRLAASDLEGCAVASGPFRPIQTSQLTDEELLSLPKCCQPDAADKASVLEPGRPASAGNALKGRVPPGDTPPGNGSGPRHINDSPFGTLPSSAEPPLTALRPGGSEPPGLPTTGPRRRPGCSRKNRTRSHCRLGQAGSGASGTGDAEGSGALPALACSLAPLGLALVLWTVLGPC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99M75-1", "uniprot_id": "RTN4R_RAT", "id": "Q99M75-1", "name": "Reticulon-4 receptor", "aln": "MKRASSGGSRLLAWVLWLQAWRVATPCPGACVCYNEPKVTTSCPQQGLQAVPTGIPASSQRIFLHGNRISYVPAASFQSCRNLTILWLHSNALAGIDAAAFTGLTLLEQLDLSDNAQLRVVDPTTFRGLGHLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLVPLRSLQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCNLPQRLAGRDLKRLAASDLEGCAVASGPFRPFQTNQLTDEELLGLPKCCQPDAADKASVLEPGRPASAGNALKGRVPPGDTPPGNGSGPRHINDSPFGTLPGSAEPPLTALRPGGSEPPGLPTTGPRRRPGCSRKNRTRSHCRLGQAGSGSSGTGDAEGSGALPALACSLAPLGLALVLWTVLGPC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZR6-1", "uniprot_id": "RTN4R_HUMAN", "id": "Q9BZR6-1", "name": "Reticulon-4 receptor", "aln": "MKRASAGGSRLLAWVLWLQAWQVAAPCPGACVCYNEPKVTTSCPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCSLPQRLAGRDLKRLAANDLQGCAVATGPYHPIWTGRATDEEPLGLPKCCQPDAADKASVLEPGRPASAGNALKGRVPPGDSPPGNGSGPRHINDSPFGTLPGSAEPPLTAVRPEGSEPPGFPTSGPRRRPGCSRKNRTRSHCRLGQAGSGGGGTGDSEGSGALPSLTCSLTPLGLALVLWTVLGPC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:***************:**:***************************.****:************:******::************.** *********:*************: ***:**:***:***********:********************* ******:******************.****:****************:**:*********************** **:*.* ***:************************************.******.********.**:*****:**::*: *.: **** *.************************************:********************.********:** ******:**:**************************..****:*******:*:***:***************", "identical_positions": 419, "similar_positions": 45, "identity": "88.58%" }, { "cls_id": "homologset.agr.RGD:620811", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63633-1", "uniprot_id": "S12A5_RAT", "id": "Q63633-1", "name": "Solute carrier family 12 member 5", "aln": "MSRRFTVTSLPPAASAASADPESRRHSVADPRRLPREDVKGDGNPKESSPFINS--TDTEKGREYDGRNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSKEHEEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEDASG--EAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRLWGLFCSSRLLNATCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERRGMPSVGLADGTPVDMDHPYVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLVRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLDNHPQAQRAEESIRRLMEAEKVKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQILKQMHLTKNEREREIQSITDESRGSIRRKNPANTRLRLNVPEETACDN-EEKPEEE---------VQLIHDQSAPSCPSSSPSPGEEPEGEGETDPEKVHLTWTKDKSAAQKNKGPSPVSSEGIKDFFSMKPEWENLNQSNVRRMHTAVRLNEVIVNKSRDAKLVLLNMPGPPRNRNGDE--NYMEFLEVLTEQLDRVMLVRGGGREVITIYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V14-1", "uniprot_id": "S12A5_MOUSE", "id": "Q91V14-1", "name": "Solute carrier family 12 member 5", "aln": "MSRRFTVTSLPPAASAASADPESRRHSVADPRRLPREDVKGDGNPKESSPFINS--TDTEKGREYDGRNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEDASG--EAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRLWGLFCSSRLLNATCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERRGMPSVGLADGTPVDMDHPYVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLVRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLDNHPQAQRAEESIRRLMEAEKVKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQILKQMHLTKNEREREIQSITDESRGSIRRKNPANPRLRLNVPEETACDN-EEKPEEE---------VQLIHDQSAPSCPSSSPSPGEEPEGERETDP-EVHLTWTKDKSVAEKNKGPSPVSSEGIKDFFSMKPEWENLNQSNVRRMHTAVRLNEVIVNKSRDAKLVLLNMPGPPRNRNGDE--NYMEFLEVLTEQLDRVMLVRGGGREVITIYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2X9-1", "uniprot_id": "S12A5_HUMAN", "id": "Q9H2X9-1", "name": "Solute carrier family 12 member 5", "aln": "MSRRFTVTSLPPAGPARSPDPESRRHSVADPRHLPGEDVKGDGNPKESSPFINS--TDTEKGKEYDGKNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEDASG--EAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRLWGLFCSSRFLNATCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERSGMTSVGLADGTPIDMDHPYVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLVRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLENHPQAQRAEESIRRLMEAEKVKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQILKQMHLTKNEREREIQSITDESRGSIRRKNPANTRLRLNVPEETAGDS-EEKPEEE---------VQLIHDQSAPSCPSSSPSPGEEPEGEGETDPEKVHLTWTKDKSVAEKNKGPSPVSSEGIKDFFSMKPEWENLNQSNVRRMHTAVRLNEVIVKKSRDAKLVLLNMPGPPRNRNGDE--NYMEFLEVLTEHLDRVMLVRGGGREVITIYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JWE2-1", "uniprot_id": "A0AC58JWE2_DANRE", "id": "A0AC58JWE2-1", "name": "", "aln": "MSQRFTVTTGDIQGEVN--QLFEGDEETPSTAAAAGGSGKGDGNPKESSPFINS--TDPEKNQQFDGKNMALFEDEMDTIPMVSSLLSSLANYSNLPQGSKEHEEAENNEGSRKKPVQAPRMGTLMGVYLPCLQNILGVILFLRMTWMVGIGGVIEAFIIVLMCCSTTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGICFYLGTTYAGAMYILGCIEILLVYIVPQAAIFKMEGLEGAEAEAAMLNNMRVYGTLVLSFMAIVVFVGVKYVNKLALVFLACVICSILAVYAGVIKTAFEPPVFPVCVLGNRTLVWKGFDVCAKVIERENATVTTKLWRLFCDSEFLNATCDTYFTNNNVTEMQGIPGVMSGTLRENLFGNYMDKGAFIEKTGLSSVVEPDSIPTNTNR-YVLADITSFFTMLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPIGTILAITTTSIIYMSSVVLFGACIEGTVLRDKFGEAVRGNLVIGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLMQAIARDGIVPFLRVFGHGKANGEPTWALLLTACICESGILIASLDNVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFKFYHWTLSFLGMSLCLSLMFICSWYYAIVAMGIAGCIYKYIEFRGAEKEWGDGIRGLSLSAARFALMRLEEGPPHTKNWRPQILVLVNMDGELKVDQPRMLSLTSQLKAGKGLTIVGTALEGTYLENHDQGQQAEQSLRKLMETEKVKGFSQVVISSNMRDAMSHLVQASGLGGLQHNTVLASWPRNWKQAEDHQSWRNFIELVRETTAGSKALLVPKNISAFPSNGERFTEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRIDAAVEVVEMHDSDISAYTYEKTLMMEQRSQILKQINLTKTEREREIQSITDSSRGSIRRKNPAAVTTQLSVTEEPAASSKEQKPEEECVPVSPSQQEQLIHDKSTN--PPTPATP-QSPSADAQTPGTAVQMTWSEVKCDGEQNKPVGATTPEAIKDLFNMKPEWENLNQSNVRRMHTALRLNEVIIKKSQEAKLVLLNMPGPPRNRSGDE--NYMEFMEVLTEGLNRVLLVRGGGREVITIYS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B534-1", "uniprot_id": "A0A8M3B534_DANRE", "id": "A0A8M3B534-1", "name": "", "aln": "-----------MMNNLN--ECEEGD---------GGPNSQGDATSKESSPFINSSTSDVEKSQQYDGKNMALFEEEMDTSPMVSSLLSSLANYSNLTQGSKEHEEAENNEEARKKAAQAPRMGTIMGVYLPCLQNILGVILFLRMTWLVGVGGVLGTFTIVFMCCSTTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGICFFLGTTFAGAMYILGCIEILLIYIVPSAAIFKMEGLEGSEAEAALLNNMRVYGTIVLTFMAIVVFVGVKYVNKLALVFLACVILSILAIYAGVIKTSFDPPDFPVCVLGNRTLVSKAYDICAKTIERGNATITTKLWRSFCDSEFLNATCDEYFVNNNISQIQGIPGVTSGILAENLFSGYMEKNSVLEKRGLQAVQDPELPVTNSNR-YVLADITSFFTLLVGIYFPSVTGIMAGSNRSGDLQDAQKSIPVGTILAITTTSIIYMSSVILFGACVDGVVLRDKFGEGVSGNLVIGTLAWPSPWVIVFGSFFSTCGAGLQSLTGAPRLLQAIARDGIIPFLRVFGHGKANGEPTWALLLTACICESGILIASLDAVAPILSMFFLMCYMFVNLACALQTLLRTPNWRPRFKFYHWALSLLGMSLCLTLMFLCSWYYAIVAMVIAGCIYKYIEFCGAEKEWGDGIRGISLSAARFALMRLEEGPPHTKNWRPQILVLTTLDGEQNVEQPRLLSLTSQLKAGKGLTIVGACIEGTYLNNQPKTQKADQSLRKLMEVEKVKGFSQVVISSNLRDATSHLIQAGGLGGLRHNTVLVSFPKNWKQAEEHHRCRNFIEVVRETTAGHMALLVPKNISAYPSNGERFTEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCKMRIFTVAQMDDNSIQMKKDLMTFLYHLRLDAAVEVVEMLDNDISAYTYEKTLMMEQRSQILKEMHLTKNEREREIQSITDVSRGSIRRKNPSNLHPQRSIAEESVAGSGEEKPEEESVRVSHPRQVQLIQGKNATPTPTSPTSP-TAPTPATMSPGEEIQMTWTD---DTEKANNPAVANPENIKDMFNMKPEWENLNQSNVRRMHHAQKLNEVIVKKSQEAKLVLLNMPGPPRNRTGEE--NYMEFLEVLTEGLNRVLLVRGGGREVITIYS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4LGD3-1", "uniprot_id": "A0A0B4LGD3_DROME", "id": "A0A0B4LGD3-1", "name": "", "aln": "-----------MQSNSAKDDSDEMEIIP------SEHNGTVHETKNEDSGDIHR---AEENQKSSIDPNLYLYDDDLETRPHISTFISSIANYENTIPAAT--------DPDAKPAAPSARMGTLIGVFLPCIQNIFGVILFIRLTWVVGTAGAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGMLFYTGTTLAAAMYIVGAVEIVLTYMAPWASIFGDFTKDA----DAMYNNFRVYGTLLLIFMGLIVFLGVKFVNKFATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLLKDIPLENCTKED--------SFLRDIYCP----DGKCEEYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKGQFIS-YGKSAIDIENTSGESYNQ--IMADITTSFTLLIGIFFPSVTGIMAGSNRSGDLADAQKSIPIGTICAILTTSTVYLSSVMFFAGTVDNLLLRDKFGQSIGGKLVVANIAWPNQWVILIGSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKSSKRGEPTRALLLTIVICQCGILLGNVDLLAPLLSMFFLMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLIGLTLCISVMIMTSWYFALIAMGMAIIIYKYIEYRGAEKEWGDGIRGMALTAARYSLLRLEEGPPHTKNWRPQILVLSKLNDNLLPKYRKIFSFATQLKAGKGLTICVSVIKGDHTKITNKAVDAKATLRKYMTDEKVKGFCDVLVAQQIGEGLSSVIQTIGLGGMKPNTVIIGWPYSWRQ-EGRNSWKTFIQTVRTVAACHMALMVPKGINFYPESNHKIG-GNIDIWWIVHDGGLLMLLPFLLKQHRTWRNCKLRIFTVAQIEDNSIQMKKDLKTFLYHLRIEADVEVVEMNNSDISAYTYERTLMMEQRNQMLRALGLNKKENSKVVQTIMD------YKETPSDNK--MSLVQTIVDHHYDATKTAS---------------KVRFADPTIEETQHHDSQNDEKRNSIDLDGPENADTPETTSNKDESTEKADG-----DFKSSVK-PDEFNVRRMHTAIKLNEVIVEKSQDAQLVIMNLPGPPREVRAERERNYMEFLEVLTEGLEKVLMVRGGGREVITIYS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . :*.* *: *: :. . *: *::::::* * :*:::*.:*** * .: : * .. :.****::**:***:***:*****:*:**:** .* : * :*: **. ***********************:***************: *: *** *.****:* :**:* *: * :** .. *: **:***** :* *. :**:***:***:* * *.*** **:*:*.*::.. . : :*:**:* * : *:* : * :* :..*: *: **:::::** * ** : :*:: .:: *. .:. * :: : . :: :::*:*: **:*:**:***************** ******* *** ** *** :*:***::*.. ::. :******:.: *:**:..:***. ***::***:** *************:***:** *:*** *.:.. .**** ***** **: ***:..:* :**:********* *******:*************::***:**::*::**:::*:: ***:*::** :* ******: ************::*:***::*:***************:*** :: : :::*:::********** : ::* . . : *. ::*: * ******.:*:::.:: :. * ::*: ****:: ***: .:* .*:* * :: :.**: ** .:* **:*.*.:. :* . .:: * **:********:********::*:.**:**:*******::********** *******: * ****** :.********:**:****.*:*: : *.*.*..: :*:* * ::.*: .: : . : . . : *. : . :. . . . : . ..: .:*.. : :: ****** * :*****::**::*:**::*:*****: .:. *****:***** *::*::*************", "identical_positions": 510, "similar_positions": 310, "identity": "44.16%" }, { "cls_id": "homologset.agr.RGD:620812", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SQ27-1", "uniprot_id": "Q5SQ27_MOUSE", "id": "Q5SQ27-1", "name": "", "aln": "---------------------MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEAMLRKYMEFRKTMDIDHILDWQPPE---------VIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCER-ILHECDLQTERLGRKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIVVLGSNSWKEGLLKLISPEELPAHFGGTLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQISRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTKMGERQKAGEMVEVLTSQRYNAHMVPEDGSLTCSEAGVYVLRFDNTYSFVHAKKVSFTVEVLLPDEGMQKYDEELTPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z1J8-1", "uniprot_id": "S14L3_RAT", "id": "Q9Z1J8-1", "name": "SEC14-like protein 3", "aln": "---------------------MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEAMLRKYMEFRKTMDIDHILDWQPPE---------VIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCER-ILHECDLQTERLGRKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIVVLG-NSWKEGLLKLISPEELPAHFGGTLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQISRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTKMGERQKAGEMTEVLTSQRYNAHMVPEDGSLTCTEAGVYVLRFDNTYSFVHAKKVSFTVEVLLPDEGMQKYDEELTPI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UDX4-1", "uniprot_id": "S14L3_HUMAN", "id": "Q9UDX4-1", "name": "SEC14-like protein 3", "aln": "---------------------MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEALLRKYMEFRKTMDIDHILDWQPPE---------VIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCER-ILHECDLQTERLGKKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIIVLG-NNWKEGLLKLISPEELPAQFGGTLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQINRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTKMGERQRAGEMTDVLPSQRYNAHMVPEDGNLTCSEAGVYVLRFDNTYSFVHAKKVSFTVEVLLPDEGMQKYDKELTPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33324-1", "uniprot_id": "YKJ1_YEAST", "id": "P33324-1", "name": "CRAL-TRIO domain-containing protein YKL091C", "aln": "MTTS----ILDTYPQICSPNALPGTPGNLTKEQEEALLQFRSILLEKN-YKERLDDSTLLRFLRARKFDINASVEMFVETERWREEYGANTIIEDYENNKEAEDKERIKLAKMYPQYYHHVDKDGRPLYFEELGGINLKKMYKITTEKQMLRNLVKEYELFATYRVPACSRRAGYLIETSCTVLDLKGISLSNAYH-VLSYIKDVADISQNYYPERMGKFYIIHSPFGFSTMFKMVKPFLDPVTVSKIFILG-SSYKKELLKQIPIENLPVKYGGTSV-----------------------LHNPNDKFYYSDIGPWR-----------------------DPRYIGP-------------EGEIPNIFGKFTVTS--------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P24280-1", "uniprot_id": "SEC14_YEAST", "id": "P24280-1", "name": "SEC14 cytosolic factor", "aln": "MVTQQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAG-FIERLDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYD------EKPLIAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVWEYESVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYS-VMSYVREASYISQNYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILG-SSYQKELLKQIPAENLPVKFGGKSE-----------------------VDESKGGLYLSDIGPWR-----------------------DPKYIGP-------------EGEAPEAFSMK------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* *:* * ::* ::*. : : . ** ***:****:**:: : :: : .:*: . : *:: : : * * *:** *:::: :* :: : : .::: :*:. : : * :. :. * :** ::* :*:.:. : ::. :: : :: *** : : *:::. *.. :.:.****. * **.:** ..::: *** *. *:**.::**. : : * .: * * ** ** : : ", "identical_positions": 63, "similar_positions": 100, "identity": "14.58%" }, { "cls_id": "homologset.agr.RGD:620813", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08984-1", "uniprot_id": "LBR_RAT", "id": "O08984-1", "name": "Delta(14)-sterol reductase LBR", "aln": "-----------------------------------------------------MPGRKFADGEVVRGRWPGSSLYYEVEILSHDSTSQLYTVKYKDGTELELKESDIKPLKSFKQR-KSGSTSSSPSRRRS-SRSRSRSRSR--SPGRAPKG----------------------------------SRRSVSASYQADAKEK---EMRREILQVKLTPLVLKPFANSVSVYNGEPEHMEKSATPPKNKQERVILSTEDSYIATQYSLRPRREEVKPKHRVRG-TNLVTRGPVPLGTFQVTTPQRRDLEFGGVPGALLIMLGLPACVFLLLLQCA---------QKDPGLLQFPPPLPALRELWEARVCGVYLLWFFLQALFSLLPVGKVVEGTPLVDGRRLKYRLNGLYA----FILTSAAVGTAVFWDIELYYLYTHFLQFALAAIVFSVVLSVYLYARSLK--------VPRDE--LSP-ASSGNAVYDFFIGRELNPRIGAFDLKFFCELRPGLIGWVVINLVMLLAEMKVQ-------------------ERSAPSLAMTLVNSFQLLYVVDALWFEEALLTTMDIIHDGFGFMLAFGDLVWVPFTYSLQAFYLVNHPQDLSWPLTSVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIPTSTWKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHILP-YFYVIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U9G9-1", "uniprot_id": "LBR_MOUSE", "id": "Q3U9G9-1", "name": "Delta(14)-sterol reductase LBR", "aln": "-----------------------------------------------------MPSRKFVEGEVVRGRWPGSSLYYEVEILSHDNKSQLYTVKYKDGTELELKESDIKPLKSFKQR-KSGSISSSPSRRRG-SRSRSRSRSRSRSPGRAPKG----------------------------------SRRSVSASHEGDVKEKKEKEMRREILQVKLTPLVLKPFGNSVSVYNGEPEHMEKNATPYKDKQERIILSTEDRYIVTQYSLRPRREEVKAKEIESEEQNLVTKGPAPLGTFQVTTPQRKDLEFGGVPGAVLIMLGLPACVLLLLLQCR---------QKDPGLLHFPPPLPALHELWEPRVCGVYLLWFFVQALFHLLPVGKVAEGTPLVDGRRLQYRLNGLYA----FILTSAALGAAVFWGVELCYLYTHFLQLALAATGFSVLLSAYLYVRSLR--------APREE--LSP-ASSGNAVYDFFIGRELNPRLGAFDLKFFCELRPGLIGWVVINLVMLLMEMKIQ-------------------ERAAPSLAMILVNSFQLLYVVDALWNEEALLTSMDIMHDGFGFMLAFGDLVWVPFTYSLQAFYLVSHPHDLSWPLASVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHLLP-YFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14739-1", "uniprot_id": "LBR_HUMAN", "id": "Q14739-1", "name": "Delta(14)-sterol reductase LBR", "aln": "-----------------------------------------------------MPSRKFADGEVVRGRWPGSSLYYEVEILSHDSTSQLYTVKYKDGTELELKENDIKPLTSFRQR-KGGSTSSSPSRRRG-SRSRSRSRSP----GRPPKS----------------------------------ARRSASASHQADIKEA------RREVEVKLTPLILKPFGNSISRYNGEPEHIERNDAPHKNTQEKFSLSQESSYIATQYSLRPRREEVKLKEIDSKEEKYVAK-ELAVRTFEVTPIRAKDLEFGGVPGVFLIMFGLPVFLFLLLLMCK---------QKDPSLLNFPPPLPALYELWETRVFGVYLLWFLIQVLFYLLPIGKVVEGTPLIDGRRLKYRLNGFYA----FILTSAVIGTSLFQGVEFHYVYSHFLQFALAATVFCVVLSVYLYMRSLK--------APRND--LSP-ASSGNAVYDFFIGRELNPRIGTFDLKYFCELRPGLIGWVVINLVMLLAEMKIQ-------------------DRAVPSLAMILVNSFQLLYVVDALWNEEALLTTMDIIHDGFGFMLAFGDLVWVPFIYSFQAFYLVSHPNEVSWPMASLIIVLKLCGYVIFRGANSQKNAFRKNPSDPKLAHLKTIHTSTGKNLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHILP-YFYIIYFTMLLVHREARDEYHCKKKYGVAWEKYCQRVPYRIFPYIY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PP65-1", "uniprot_id": "A0A8M9PP65_DANRE", "id": "A0A8M9PP65-1", "name": "Delta(14)-sterol reductase LBR", "aln": "-----------------------------------------------------MPPARFQIGDTVMGRWPGSNLYYEVKVMSFDNKTRLYTVIYKDGTELELKESDITSVVIFQTAGRSRSRSRSPGRSPGRSSARSPGRPR-RSRSRSPAR----------------------------------TPRRASSRSTEVRKEK-----LKEVLEVRLTPVAMKHENNSSNSKSEKKEENNTAKAAPVVTEEKTETESEN-QTGGRYNLRRRKDQGDGKAVELE---KAVESEPLLQTKAPAAVKTADLEFGGRVGVLFLMFLLPVAVLVLLILCG---------QKDASLQSFPLELPALQSVWDCQVFGIVLLWLLFQAVLSLLPVGKLVEGMPLKNGKTLKYRINGFYA----LLLTAVAAGVAVYQEVDLSYIHAHFLQFYTSALLIATLLSIYLFIRSRW--------ASKDE--LAPGGNSGYIIYDFFMGRELNPRIKSFDIKFFCEMRPGLMGWVLINFAMLLAEMKQQ-------------------NLENPSPAMLLVNIFQLLWVIDGLWHEEKLLTMMDIMYDGFGFMLTFGDLAFVPFTFTCQAYYLVNHPNELSVFWIITLIAMNGVGYYIFRKANSQKFAFRKNPSDPAVSHLKTIPTATGKSLIVSGLWGFVRHPNYLGDIIMALAWSLPCGFNNLVP-YFYLIYLVTLLVHRNARDERQCRKKYGSAWEEYCKAVPYRIFPRVY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32462-1", "uniprot_id": "ERG24_YEAST", "id": "P32462-1", "name": "Delta(14)-sterol reductase ERG24", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSALNPRTTEFEFGGLIGALGISIGLPVFTIILNQMIRPDYFIKGFFQNFDIVELWNGIKPLRYYLGNRELWTVYCLWYGILAVLDVILPGRVMKGVQLRDGSKLSYKINGIAMSTTLVLVLAIRWKLTDGQLPELQYLYENHVSLCIISILFSFFLATYCYVASFIPLIFKKNGNGKREKILALGGNSGNIIYDWFIGRELNPRLGPLDIKMFSELRPGMLLWLLINLSCLHHHYLKT-------------------GKIN--DALVLVNFLQGFYIFDGVLNEEGVLTMMDITTDGFGFMLAFGDLSLVPFTYSLQARYLSVSPVELGWVKVVGILAIMFLGFHIFHSANKQKSEFRQG----KLENLKSIQTKRGTKLLCDGWWAKSQHINYFGDWLISLSWCLATWFQTPLT-YYYSLYFATLLLHRQQRDEHKCRLKYGENWEEYERKVPYKIIPYVY", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8MLV1-1", "uniprot_id": "LBR_DROME", "id": "Q8MLV1-1", "name": "Lamin-B receptor", "aln": "MQHSPSTTTDHIHFAARFFDRNSYTMDRRLRRPRRTEDVSSGPLLAQSKQPSLLPVTRRTGSVTAAGATATATATAGPATRTRASPSRNKVVAPPSPDLGPRTRRSSRPRSSVGPLTGSGSGSSLPIKAAIKARTPIPEVSEVSSPIRLSTSNLPMTLTTNTSSGAPNKAFNTSSVNSGNSFSRTTTSSTTTTTERIEIRAEGDGEVDTDSIRKRITERLRRSVSKTISNLAGTPVTNTEEGSRYSRSVSRSVYDDEKSSKRSYSTGEEDIDEEDELEEDQFRSFNVTRKSATPAEISCRQLKAP-REFGGWLGAFLFLLLLPTAVYYLTWSCTARN---ACQFKHLNLGILLDVNYLTRQVFQPRVVGAFAAYQVVVFLLVALLPGRRVHLT------RETYKFNCLAVS---LTLLIASGVAEYLKYPVVTFVLRHYLRFCIFGLVGAFVAAAWSYWLVDT-----AKYNVLRQTLTNDYGRTGSFVVDFALGRQLNPKWLGRVDWKQFQYRLSLVTTLIYATCYIYQTLVWPQKPQLGEQEGYLYQAKYYWNNVNYDPATLFSASCLLFYVLDAIIFEHHLSSSFELQHEGYGCLLLLRYAATPYLLTAVTKYFYEQRVPISCWYAPLAVAALLSLGLLVKRFSCAYKYKYRLNSQSPIFANIETIHTYQGSRLLLSGMWGWVRQPNYLGDIVALLALAAPMALRPAWPPVLGLSLIILLLLHRATRANARNQARYHSSWQRYSTQVRSYILPRVY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **** *.. : : **. * : : : : .: : . :: : *: . *::* : . : . :: :.: : . . . : : : : . :* : *: :**:***: : * .:: :: : * : :::.*.: *. : : ::: :*:* :* : : : : : .: * : : : * :* . . ::::* * . *: .* *. :: **:** : *: . . :. . : **:** * : : : :* *:.* * *:* :*", "identical_positions": 50, "similar_positions": 109, "identity": "6.59%" }, { "cls_id": "homologset.agr.RGD:620814", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62805-1", "uniprot_id": "H4_HUMAN", "id": "P62805-1", "name": "Histone H4", "aln": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62804-1", "uniprot_id": "H4_RAT", "id": "P62804-1", "name": "Histone H4", "aln": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84040-1", "uniprot_id": "H4_DROME", "id": "P84040-1", "name": "Histone H4", "aln": "MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P62806-1", "uniprot_id": "H4_MOUSE", "id": "P62806-1", "name": "Histone H4", "aln": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02309-1", "uniprot_id": "H4_YEAST", "id": "P02309-1", "name": "Histone H4", "aln": "MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*******************:********************************.*.*** ***.****:*************::******************", "identical_positions": 94, "similar_positions": 8, "identity": "91.26%" }, { "cls_id": "homologset.agr.RGD:620815", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BJU0-1", "uniprot_id": "SGTA_MOUSE", "id": "Q8BJU0-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein alpha", "aln": "-MDNRKRLAYAIIQFLHGQLRHGG--LSCDAQESLEVAIQCLETAFGVTLEDSDLALP------QTLPEIFEAATSSKQ-EMPQDPRAPDRTPPSE-------------------EDSAEAERLKTEGNEQMKLENFEAAVHLYGKAIELNPANAVYFCNRAAAYSKLGNYVGAVQDCERAIGIDPGYSKAYGRMGLALSSLNKHAEAVAYYKKALELDPD--NDTYKSNLKIAELKLREAP---------SPTGGVGSLDIAGLLNNPHFITMASS----LMNSPQLQQLMSGMIS--GGHNPLGTPGSSPQQSDLASLIQAGQQFAQQMQQQNPEFVEQIRSQVVRSRTPSASHEEQQE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70593-1", "uniprot_id": "SGTA_RAT", "id": "O70593-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein alpha", "aln": "-MDNRKRLAYAIIQFLHGQLRHGG--LSSDAQESLEVAIQCLETAFGVTLEDSDLALP------QTLPEIFEAATASK--EMPQDPRGPDRTPPSE-------------------EDSAEAERLKTEGNEQMKLENFEAAVHLYGKAIELNPANAVYFCNRAAAYSKLGNYVGAVQDCERAIGIDPGYSKAYGRMGLALSSLNKHAEAVAYYKKALELDPD--NDTYKSNLKIAELKLREAP---------SPTGGVGSLDIAGLLNNPHFITMASS----LMNSPQLQQLMSGMIS--GGHNPLGTPGSSPQHSDLASLIQAGQQFAQQMQQQNPEFVEQIRSQVVRSRTPSASHEEQQE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43765-1", "uniprot_id": "SGTA_HUMAN", "id": "O43765-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein alpha", "aln": "-MDNKKRLAYAIIQFLHDQLRHGG--LSSDAQESLEVAIQCLETAFGVTVEDSDLALP------QTLPEIFEAAATGK--EMPQDLRSPARTPPSE-------------------EDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPD--NETYKSNLKIAELKLREAP---------SPTGGVGSFDIAGLLNNPGFMSMASN----LMNNPQIQQLMSGMIS--GGNNPLGTPGTSPSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQ-IRSRTPSASNDDQQE----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q12118-1", "uniprot_id": "SGT2_YEAST", "id": "Q12118-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein 2", "aln": "MSASKEEIAALIVNYFSSIVEKKE--ISEDGADSLNVAMDCISEAFGFEREAVSGILGKSEFKGQHLADILNSASRVPESNKKDDAENVEINIPEDD-----------------AETKAKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNATEAMKRDYESAKKKVEQSLNLEKTVPEQSRDADVDASQGASAGGLPDLGSLLGGGLGGLMNNPQLMQAAQKMMSNPGAMQNIQKMMQDPSIRQMAEGFASGGGTPNLSDLMNNPALRNMAGNLFGGAGAQSTDETPDNENKQ", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VJD4-1", "uniprot_id": "Q9VJD4_DROME", "id": "Q9VJD4-1", "name": "", "aln": "---MPDAVQQSFVRSFIDYLKKQGDVMSPDQTESIEVAIQCLQAAFDLGDDVEAAPAAAGE--EQATTQSSSTASAPDDDAVASGSAGIGAAAAAVPNNIDMFELFQSLYTERNPESLALAESIKNEGNRLMKENKYNEALLQYNRAIAFDPKNPIFYCNRAAAHIRLGENERAVTDCKSALVYNNNYSKAYCRLGVAYSNMGNFEKAEQAYAKAIELEPD--NEVYKSNLEAARNARNQPP-----------QTGRLREDLINMLSQPMVRNLFNN---AEIDVEQLLSMLQNPMIMNTIRQQFGGGNAPTLPNDMVQMIYN----------MTSQLTGFPNSNANPGNEQQPGNQPPPST---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ::. : . :.: :* * :*::**::*:. **.. : * .: .:*: .. . * * ** :* :**. * :.:: *: * .** . * *.:::.*****: * : ** *.: *: : * :.* *:*.* .: :* * *.:::: * .:. * : : *. .:. . : . . * . .: .. :: *: . . : : : . ::.. : . .: . .. .: . ", "identical_positions": 47, "similar_positions": 103, "identity": "12.88%" }, { "cls_id": "homologset.agr.RGD:620816", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JID1-1", "uniprot_id": "PDCD4_RAT", "id": "Q9JID1-1", "name": "Programmed cell death protein 4", "aln": "MDVENEQILNVN---PTDPDNLSDSLFSGDEENAGTEEIKNEING-------NWISA--STINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEAVRSGVAVPTSPK--GRLLD---------------RRSRSG-KGRGLPKKGGAGGKGVWGTPG-QVYDVEEVDVKDPNYDDDQE--NCVYETVVLPLDETAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCV----QARAALDKATVLLSMSKG-GKRKDSVWGSGGGQQPVNHLVKEIDMLLKEYLLSGDMSEAEHCLKELEVPHFHHELVYEAIVMVLESTGESAFKMMLDLLKSLWKSSTITIDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61823-1", "uniprot_id": "PDCD4_MOUSE", "id": "Q61823-1", "name": "Programmed cell death protein 4", "aln": "MDIENEQTLNVN---PTDPDNLSDSLFSGDEENAGTEEIKNEING-------NWISA--STINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEAVRSGVAVPTSPK--GRLLD---------------RRSRSG-KGRGLPKKGGAGGKGVWGTPG-QVYDVEEVDVKDPNYDDDQE--NCVYETVVLPLDETAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCV----QARAALDKATVLLSMSKG-GKRKDSVWGSGGGQQPVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIVMVLESTGESAFKMILDLLKSLWKSSTITIDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53EL6-1", "uniprot_id": "PDCD4_HUMAN", "id": "Q53EL6-1", "name": "Programmed cell death protein 4", "aln": "MDVENEQILNVN---PADPDNLSDSLFSGDEENAGTEEIKNEING-------NWISA--SSINEARINAKAKRRLRKNSSRDSGRGDSVSDSGSDALRSGLTVPTSPK--GRLLD---------------RRSRSG-KGRGLPKKGGAGGKGVWGTPG-QVYDVEEVDVKDPNYDDDQE--NCVYETVVLPLDERAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTTDVEKSFDKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCV----QARAALDKATVLLSMSKG-GKRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITVDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L8Y5-1", "uniprot_id": "Q1L8Y5_DANRE", "id": "Q1L8Y5-1", "name": "Programmed cell death protein 4", "aln": "MATDCEAWLNAN---PVEAGNLSDSFPSGDEDSTFTANVNNEING-------NWISAPTSTIHEARLKAKVKRRLRKNSSRDSGRGDSLSDNG-EAVRS-VVPPTSPK--GKLLN---------------RRSRTG-KGRGLPKKGGAGGKGVWGTPG-EVYGEDEVDYKDPNYDAEQE--NCVYETVVLPLDEEAFEKTVTPIVQEYFEHGDANEVAELLAELNLGSMRGDVPMLAVSLALEAKASHRELTSRLLSELCGRVLTAGDVQASFHKLLKELPDLVLDTPGAPQMLGQFIARAVADSILPKTFLDGYKGRVDCE----YARAALDRAAVLLRMSRWTGLRIDSLWGSGGGQRPVTQLIKEVNLLLKEYLLSGDTVEAERCLRELEVPHFHHEFVYEAVIMVLESTGERTLQMLLQLLKCLCSSTIITVDQMRRGFERVYLDMPDISIDVPCAYSILERFVEQSFNAGVIDRKLRDLCPSRGRKRLISEGDGGHLKLQNY----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY91-1", "uniprot_id": "Q9VY91_DROME", "id": "Q9VY91-1", "name": "Programmed cell death protein 4", "aln": "MEVESNNKRATNGGRHFTPPSDSDSKESSVERELNEEIEAVELNGSGGGGHSNGHVKKLMAVEDGRIKRKAKRLIQRQNSGSGGSANQTNGNGAAGAGGAHGASVMPLGINRIMPSPGGYVVPHRRWKNSRRSRTINRGRGLPKKGGGGGKGVWGLPGSEALAEVYEDENDPNYDSECNDRNVELREVITEITREEFFKLAEPIVLEYYEHGDPHEVALSFDEILQAPMREHVTSILVEIAMDHKDSQREMTSVLISDLYGRVITGKDIEKGFNMLLANLPDLVLDTPEAPIMLGNFMARAVADDCIPPKFVAKSGEELRHLGLGEHAEQALRRADSLIYKHVW--AHLDNVWGMGGPLRPVKTITMQMELLLKEYLSSRDVAEAQRCLRALEVPHYHHELVYEAIVMTLESLSQTTEEAMCELLKQLDLTCLVLPAGMEQGFLRAFDDMADIVLDVPLAYIILDRFVERCNRAGFLTDKIINNVPSRGRKRFVSEGDGGHVKPTTFTMRD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : .* . . *** *. * . *:** * ::.:.*:: *.** ::::.* ..* .:. ...* . . .. * .::: ****: :*********.******* ** :. * :***** : : * . *: : . * * **: **:****.:*** : :: . *: *. : *.:*:: * *:**:** *:*:* * *:: *:: .*. ** :**:*.**** ** ::*:*:****.*. : .:: : *. ** :* *: : *.:** ** :.*. : ::::****** * * **::**: *****:***:****::*.*** .: : : : :*** * : : *.:*: * : ::.** :*** :* :*:****.. .**.: :: : *******::******::* .: ", "identical_positions": 170, "similar_positions": 143, "identity": "33.27%" }, { "cls_id": "homologset.agr.RGD:620817", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JM53-1", "uniprot_id": "AIFM1_RAT", "id": "Q9JM53-1", "name": "Apoptosis-inducing factor 1, mitochondrial", "aln": "--MFRCGGLAG-AFKQKLVPLVRSVCVQRPKQ--------------------------RNRLPGNLFQQWRVPLELQMAR------QMASSGPSGGKMDN--------SVLVLIVGLSTIGAGAYAYKTIKED------------------------QKR------------------------YNERIMGLGLS--------------------------------PEEKQRRAIASAAEGGSVPPIR-VPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPN--VTKTLQFRQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVHLDVRGNMVKLNDGSQITFEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRALEKISREVKSITVIGGGFLGSELACALGRKSQ-ASGIEVIQLFPEKGNMGKILPEYLSNWTMEKVKREGVKVMPNAIVQSVGVSGGKLLIKLKDGRKVETDHIVTAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDN-PKSATEQSGTGIRSESETESEASEITIPPSDPAVPQVPVEGEDYGKGVIFYLRDKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0X1-1", "uniprot_id": "AIFM1_MOUSE", "id": "Q9Z0X1-1", "name": "Apoptosis-inducing factor 1, mitochondrial", "aln": "--MFRCGGLAG-AFKQKLVPLVRTVYVQRPKQ--------------------------RNRLPGNLFQQWRVPLELQMAR------QMASSGSSGGKMDN--------SVLVLIVGLSTIGAGAYAYKTIKED------------------------QKR------------------------YNERVMGLGLS--------------------------------PEEKQRRAIASATEGGSVPQIR-APSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPN--VTKTLQFRQWNGKERSIYFQPPSFYVSAQDLPNIENGGVAVLTGKKVVHLDVRGNMVKLNDGSQITFEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRALEKISREVKSITVIGGGFLGSELACALGRKSQ-ASGIEVIQLFPEKGNMGKILPQYLSNWTMEKVKREGVKVMPNAIVQSVGVSGGRLLIKLKDGRKVETDHIVTAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDN-PKSATEQSGTGIRSESETESEASEITIPPSAPAVPQVPVEGEDYGKGVIFYLRDKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95831-1", "uniprot_id": "AIFM1_HUMAN", "id": "O95831-1", "name": "Apoptosis-inducing factor 1, mitochondrial", "aln": "--MFRCGGLAAGALKQKLVPLVRTVCVRSPRQ--------------------------RNRLPGNLFQRWHVPLELQMTR------QMASSGASGGKIDN--------SVLVLIVGLSTVGAGAYAYKTMKED------------------------EKR------------------------YNERISGLGLT--------------------------------PEQKQKKAALSASEGEEVPQDK-APSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPN--VTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKAR-ALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDN-PKSATEQSGTGIRSESETESEASEITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQ79-2", "uniprot_id": "AIFM1_DROME", "id": "Q9VQ79-2", "name": "Putative apoptosis-inducing factor 1, mitochondrial", "aln": "MSIWGVRCLTQRFIRQAYILANRRLLGPVPQRSPPAYAPLRPAHSSLYQMVKKRTLEARTKLQANKYPNHQVCVTKPSTTPPVEEYETAVEGAGVPAYANAQFQAHSQSEPLFKVGFADVKSVCSAKDVLKSDSAKLSTSQPVLDSCKATSPCEEFKRKRKETTCQPCDEDGTAPGGGDGGDEECECRMKDLRLKCLLGALAALLAGGFLAWFMTRDTDDSEAKKAEAEEEERKRRLVAGLATSPPSSEDLPKHVPYLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKELWYTPNPNEDPIKDYRFKQWTGSERSLFFEPDEFFIDPEDLDDNANGGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMLRDAPPSVLEKVMVYRTPDDFDRLRKLAAEKRSITIVGNGFIGSELACSLAHYSRENNGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPNASIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRSLGGFVVNAELEARRNLYVAGDASCFFDPLLGRRRVEHHDHSVVSGRLAGENMTGAKKPYQHQSMFWSDLGPEIGYEGIGLVDSSLPTVGVFALPSESATRVDQLSESSDSDVPETSTSSSQSSKSDAGASQDGVTCDPDEAGNYGKGVIFYLKNDKIVGILLWNLFNRIGLARTIINQNKKYDDLNEVAKLFEIHA-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *: ::* : * : *:: *.:* .* : . :* : : : * .*.. * * :: **:: : : . * ..:*.* .** : *: .* *. .*::::: * . . * . *.***:*:********:* *:*::.*. *:**::*:: . ************:: :** * :*:**.*.***::*:* .*::..:** . ***:** * .* ::*.: .:*.**** :*::::****** :*:.*. : * ..* .:. ::*. .** *.*:: * :***::*.**:******:*.: :: * :* *:* *:.**.*:**:***.** *:. :** *:*** ::*. . .* ::*::* .: :* :*..** **.:** .. **:* .:*** *****:** *::*****:**:* ***********:************** *** ***********::***.*************** .: . . .. :*.*.:.: . * :.*::*: .* .*. * :. :*********::. :***:***:***: :**.**::.::::*********:** ", "identical_positions": 270, "similar_positions": 203, "identity": "36.49%" }, { "cls_id": "homologset.agr.RGD:620818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6B3C5-1", "uniprot_id": "A0A8I6B3C5_RAT", "id": "A0A8I6B3C5-1", "name": "", "aln": "MTQPRRVASARTLALSPPLRRLSPGADWATLGTDLCLSQWTAATESAICGILARGAHKRYPRRGRVSQRHQVSLWGRRRLRRRPFGIPERSRASSAADMEPEPQPEPVTLLVKSPNQRHRDLELSGDRGWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLQDLLP----KQEKRHVLHLVCN----VRSPSKKPEASTKGAESTEQPDNTSQAQYPGDSSSDGLREREVLRNLPPSGWENVSRPE-AVQQTFQGLGPGFSG-------YTTYGWLQLSWFQQIYARQYYMQYLAATAASGAFGPTPSAQEIPVVSTPAPAPIHNQFPAENQPANQNAAAQAVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGPPQ----------------EAANQDPNNNLQGGLDP-----------------------------EMEDPNRLPVGREVLDPEHTSPSFMSTAWLVFKTFFASLLPEGPPALAN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJK5-1", "uniprot_id": "HERP1_MOUSE", "id": "Q9JJK5-1", "name": "Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein", "aln": "--------------------------------------------------------------------------------------------------MEPEPQPEPVTLLVKSPNQRHRDLELSGDRSWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLQDLLP----KQEKRHVLHLVCN----VKNPSKMPETSTKGAESTEQPDNSNQTQHPGDSSSDGLRQREVLRNLSPSGWENISRPE-AVQQTFQGLGPGFSG-------YTTYGWLQLSWFQQIYARQYYMQYLAATAASGTFVPTPSAQEIPVVSTPAPAPIHNQFPAENQPANQNAAAQAVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGGPR----------------DAANQDPNNNLQGGMDP-----------------------------EMEDPNRLPPDREVLDPEHTSPSFMSTAWLVFKTFFASLLPEGPPALAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15011-1", "uniprot_id": "HERP1_HUMAN", "id": "Q15011-1", "name": "Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein", "aln": "--------------------------------------------------------------------------------------------------MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLP----KQEKRHVLHLVCN----VKSPSKMPEINAKVAESTEEPAGSNRGQYPEDSSSDGLRQREVLRNLSSPGWENISRPE-AAQQAFQGLGPGFSG-------YTPYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRPRPVQNFPNDGPPP----------------DVVNQDPNNNLQEGTDP-----------------------------ETEDPNHLPPDRDVLDGEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLW9-1", "uniprot_id": "Q9VLW9_DROME", "id": "Q9VLW9-1", "name": "", "aln": "-------------------------------------------------------------------------------MEENAAPPAAATAAGCDAATRQKNPETSVRLLIKSSNQQYEDLNVDSDLCWTVQRLKKHLSLIYPGKPLIQDQKLIYSGKLLDDSQKISEVIRSYKDVYQQHHIFHLVCASKQVIRPAAKAPTVPQKDAVPAGPEVTGNANELRQRHAPHQQQAQQGNAGPHVTGDIGLANPWTHFWQQSQGAAPAANASASPHALFQQQALIYNAWMQQAYAQYMQQLTLRSTLPGSNQSGLPPPTQPLLPSVPLIAGRN--FGEVQQVAGAAAAPAAQVPADPQINGAPQNRNFPNIQEEPEMH-DWLDSFFSFTRLAIFVTVLYFNSSALRCLLVVLIAGAIYLYHIGVLRRRRERNNNNINRNNNAGDAAAFAAVQQIQRMMDAAVQRENNDPQAANEPGAVPAAGPAAAGEQDAIDAPPAGAPVAPASAANPEPTDVSAEAVEPPNANNSVISVVRTFVITFFTSLLPEAPAL---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .* **:**.**::.**::..* *:* :** *** :** :* :**:******** * * : ::: :::*::**** :: .:* * * * .: . : :.. : :: . .* .::.* * ** .*. .. : . : :*:** **: * :* ... *.. : : *.* * : * :* *. **. . * ...: * : :. * ::*: *:: **** :* : :::*:::*** ** * *:*: : .:**:*:* : * . :* : . :.. * **: * . :* . :*: . :.:: ::. *.:*.. .. ***:*****.*. ", "identical_positions": 105, "similar_positions": 129, "identity": "19.09%" }, { "cls_id": "homologset.agr.RGD:620819", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64270-1", "uniprot_id": "EI2BA_RAT", "id": "Q64270-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "----MEDG---ELIKYFKSQMKGDPNMASAVAAIQTLLEFLKRDKGETIQGLRAHLTKAIETLCAVDSSVA-VSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLSRISLSRTKIASLCHAFIKDGARILTHAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKVDLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKSVQAGQDLKEEH--PWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LC8-1", "uniprot_id": "EI2BA_MOUSE", "id": "Q99LC8-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "----MEDG---ELIEYFKSQMKGDPKMASAVAAIQTLLEFLKRDKGETLQGLRANLTYAIKTLCGVDSSVA-VSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLRRISLSRNKIANLCHTFIKDGARILTHAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALSHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQEDVPDKFKYKADTLKSVQTGQDLKEEH--PWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14232-1", "uniprot_id": "EI2BA_HUMAN", "id": "Q14232-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "----MDDK---ELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVDSSVA-VSSGGELFLRFISLASLEYSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEH--PWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ILD9-1", "uniprot_id": "A0A0R4ILD9_DANRE", "id": "A0A0R4ILD9-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "----MEER---ELVEYFRGQIREDPDVASAVAAIRSLLEFLKRDQSETILGLRENMTQAIHRLQEADSSVA-VSSGGELFLRFISLTSLEHPDLSQCKNVMIERGELFLKKISLSRGKVGKLCHTFIKDGAKILTHSSSRVVLKVLENAAADNKRFTVYVTESQPDSAGKLMAEKLRKLSIPVTVVLDAAVGYILEKVDLVIVGAEGVVESGGVINKIGTYQMAVCSKAHNKPFYVVAESFKFVRLYPLNQQDVPDRFKYKADVLK---TAEDLNQEH--PLIDYTPPSLITLLFTDLGVLTPSAVSDELIKLYL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAD4-1", "uniprot_id": "Q9VAD4_DROME", "id": "Q9VAD4-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "MPQITENGQDFDVVKYFLQLLDEDKDLSSGIAAIRTLLMILEKKQFGTIHILHTTMREAVAAMRNTDLSIAAIVSAGELFCRFITLS-LDDKHMEECRQIMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRILTHSRSRVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLILDSATGYVMESVDFVLVGAEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKFSRLYPLNQRDLPNEYKYSRKHLN------DVSKVH--PLVDYTPPVYITLLFTDLGRLTPSAVSDELIKLYM-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14741-1", "uniprot_id": "EI2BA_YEAST", "id": "P14741-1", "name": "Translation initiation factor eIF2B subunit alpha", "aln": "---MSEFN----ITETYLRFLEEDTEMTMPIAAIEALVTLLRIKTPETAAEMINTIKSSTEELIKSIPNSVSLRAGCDIFMRFVLRNLHLYGDWENCKQHLIENGQLFVSRAKKSRNKIAEIGVDFIADDDIILVHGYSRAVFSLLNHAANKFIRFRCVVTESRPSKQGNQLYTLLEQKGIPVTLIVDSAVGAVIDKVDKVFVGAEGVAESGGIINLVGTYSVGVLAHNARKPFYVVTESHKFVRMFPLSSDDLP----MAGPPLDFTRRTDDLEDALRGPTIDYTAQEYITALITDLGVLTPSAVSEELIKMWYD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : : * .:: :***.:*: :*. . * : : : : . . : :. ::* **: . .:*:: :::.*::*: : ** :.. ** *. **.*. **.*: * * * :*:. .. *: : * .: *:::*:*.* :::..* *:****.*.*.**:** :** :.: :: .*****::**.** *::**.. *:* *. *:.. * :***. ** *:**** *******:****:: ", "identical_positions": 86, "similar_positions": 97, "identity": "27.22%" }, { "cls_id": "homologset.agr.RGD:62082", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01069-1", "uniprot_id": "ESMB_DROME", "id": "Q01069-1", "name": "Enhancer of split mbeta protein", "aln": "----------------MVLEM-EMSKTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMKKLRAQKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMSHLGHRLNYLQ-VVVPSLPIGVPLQAPVEDQAMVTPPPSECDSLESGACSPAPS---------------EASSTSGPMWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01070-1", "uniprot_id": "ESMC_DROME", "id": "Q01070-1", "name": "Enhancer of split mgamma protein", "aln": "---------------MSSLQMSEMSKTYQYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTHLQKMKQQRQHKR--------ASGDESLTPAEGFRSGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHLGQRLNQIQPAEKEVLPVTAPLSVHIANRDAYSVPISPISSYAGSPNSNTSSTSHSLLTTIDVTKMEDDSEDEENVWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13097-1", "uniprot_id": "ESM7_DROME", "id": "P13097-1", "name": "Enhancer of split m7 protein", "aln": "----------------MATKY-EMSKTYQYRKVMKPLLERKRRARINKCLDELKDLMAECVAQTGD--AKFEKADILEVTVQHLRKLKESKKHVP--------------ANPEQSFRAGYIRAANEVSRALASLPRVDVAFGTTLMTHLGMRLNQLEQPMEQPQAVNTPLSIVCGSSSSSSTYSSASSCSSISPVSSGYASDN---------ESLLQISSPGQVWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q01071-1", "uniprot_id": "ESMD_DROME", "id": "Q01071-1", "name": "Enhancer of split mdelta protein", "aln": "---------------MAVQGQRFMTKTQHYRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKADILELTVNYLKAQQQQRVANP--------QSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDLKFGTHLMKQLGHQLKDMKQEEEIIDMAEEPVNLADQKRSKSPRE--------------------------------EDIHHGEEVWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13098-1", "uniprot_id": "ESM8_DROME", "id": "P13098-1", "name": "Enhancer of split m8 protein", "aln": "--------------------MEYTTKTQIYQKVKKPMLERQRRARMNKCLDNLKTLVAELRG--DDGILRMDKAEMLESAVIFMRQQKTPKKVAQ-----------EEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQQFHEA-QSAADFIQNSMDCSSMDKAPLSPASSGYHSDCDSP---------------APSPQPMQQPLWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13096-1", "uniprot_id": "ESM5_DROME", "id": "P13096-1", "name": "Enhancer of split m5 protein", "aln": "------------MAPQSNNSTTFVSKTQHYLKVKKPLLERQRRARMNKCLDTLKTLVAEFQG--DDAILRMDKAEMLEAALVFMRKQVVKQQAP-------------VSPLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVEFQRMLQ--------ADQVQTSVTTS--TPRPLSPASSGYHSDNEDSQS-------------AASPKPVEETMWRPW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35429-1", "uniprot_id": "HES2_RAT", "id": "P35429-1", "name": "Transcription factor HES-2", "aln": "-----------------MRLPRGVGDAAELRKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLREQPASVCSTEAPG-------------SLDSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSG-----------GPPSLTPASASAPAP-SPPVP-----------------------------PPSSLGLWRPW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54792-1", "uniprot_id": "HES2_MOUSE", "id": "O54792-1", "name": "Transcription factor HES-2", "aln": "-----------------MRLPRRVEDAAELRKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQEQPATLYSSAAPG-------------PLNSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSD-----------DSPSLTLPPAPAPAP-SPPVP-----------------------------PPGSSGLWRPW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y543-1", "uniprot_id": "HES2_HUMAN", "id": "Q9Y543-1", "name": "Transcription factor HES-2", "aln": "-----------------MGLPRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELPASSWPTAAPL-------------PCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSSGPSAPAPAPASAPEPASAPVPS-------------------------PPSPPCGPGLWRPW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TZ70-1", "uniprot_id": "A0AB32TZ70_DANRE", "id": "A0AB32TZ70-1", "name": "", "aln": "MTPNIITEAHPHSFGSRMTVAQRK-EAHELRKTLKPLMEKRRRARINDSLNHLKTLILPLVGKDASRYSKLEKADILEMTVRFLRDLPS----SSAKG-------------QTDSYKEGYKACLQRISTMLPQS-NLETEAHQRVSEFIHTCSS--------------RWRLLHRPARTAVLRTQK------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * **::*::****:* *. ** :: . :::**::** :: .:: : : ** . .:: :. :. : : ", "identical_positions": 18, "similar_positions": 33, "identity": "7.89%" }, { "cls_id": "homologset.agr.RGD:620820", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62818-1", "uniprot_id": "EI2BB_RAT", "id": "Q62818-1", "name": "Translation initiation factor eIF2B subunit beta", "aln": "-------MPGAAAKGSELSERIESFVETLKRGGGRRTSEDMARETLGLLRRLITDHHWNNAGDLMDLIRREGRRMTAAHPPETTVGNMVRRVLKIIREEYGRLHGR----SDESDQ--QESLHKLLTSGG---LSEDFSFHYAPLKSN------IIEAINELLVELEGTTENIAAQALEHIHSNEVIMTIG-FSRTVEAFLREAAQK-RKFH-VIAAECAP--FCQGHEMAVNLS-EAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANG-SLRAVAGTHTLALAAKHHSTPLIVCAPMFKLSPQFPSEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPDLITLFISNIGGNAPSYVYRLMSELYHPDDHVL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LD9-1", "uniprot_id": "EI2BB_MOUSE", "id": "Q99LD9-1", "name": "Translation initiation factor eIF2B subunit beta", "aln": "-------MPGAAAKGSELSERIEGFVETLKRGGGQRSSEDMARETLGLLRRLITDHHWNNAGDLMDLIRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGR----SDESDQ--QESLHKLLTSGG---LSEDFSFHFAPLKAN------IIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIG-YSRTVEAFLKEAARK-RKFH-VIVAECAP--FCQGHEMAVNLS-KEGIETTVMTDAAIFAVMSRVNKVIIGTKTILANG-SLRAVAGTHTLALAAKHHSTPLIVCAPMFKLSPQFPSEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPDLITLFISNIGGNAPSYIYRLMSELYHPDDHVL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49770-1", "uniprot_id": "EI2BB_HUMAN", "id": "P49770-1", "name": "Translation initiation factor eIF2B subunit beta", "aln": "-------MPGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGR----SDESDQ--QESLHKLLTSGG---LNEDFSFHYAQLQSN------IIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIG-FSRTVEAFLKEAARK-RKFH-VIVAECAP--FCQGHEMAVNLS-KAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANG-ALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76863-1", "uniprot_id": "O76863_DROME", "id": "O76863-1", "name": "Translation initiation factor eIF2B subunit beta", "aln": "-------MKEQPLK--EITQLIHAIKVGLVEG-----SYNITNKTLDIFKYIIMSKSWQNADALMQIVRDQCKILQAALPQETVTSNIARRILKLTREEFDLLHAKVQHFADDSQA--SLSLHKLVTQTSESNVSVDYSVPQHGLREA------LLDHLQEVETELETSSENICVQAEEHIHSSEIILTLG-HSRSVENFLKRAIKK-RQFLTIIVAECAP--ACRGHNLAASLANEKNVEIVVIPDAAIFAMMSRVNKVIIGTHSVLANG-GLRAACGAYTVALAAKHYSVPVIVLAPMYKLSPLHLCEQDAFNMVGCAEDVIPYDS-IPAREAKVYSPMFDYVPPELVTLFISNTGGHAPSYVYRLLTELYHPEDLEI-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32502-1", "uniprot_id": "EI2BB_YEAST", "id": "P32502-1", "name": "Translation initiation factor eIF2B subunit beta", "aln": "MSSQAFTSVHPNAATSDVNVTIDTFVAKLKRRQVQG-SYAIALETLQLLMRFISAARWNHVNDLIEQIRDLGNSLEKAHPTAFSCGNVIRRILAVLRDEVEEDTMSTTVTSTSVAEPLISSMFNLLQKPEQPHQNRKNSSGSSSMKTKTDYRQVAIQGIKDLIDEIKNIDEGIQQIAIDLIHDHEILLTPTPDSKTVLKFLITARERSNRTFTVLVTEGFPNNTKNAHEFAKKLA-QHNIETLVVPDSAVFALMSRVGKVIIGTKAVFVNGGTISSNSGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKFVEFGGSQRILPRMD--PRKRLDTVNQITDYVPPENIDIYITNVGGFNPSFIYRIAWDNYKQIDVHLDKNKA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. *. : * . * :: :** :: :* *.:.. *:: :* . : * * .*: **:* : *:* : . *:.:*: . . . * :: :: :::: *:: *.* * : **. *:::* *::* ** * .: .: ::.:* * ..*::* .*: : .:* *:.*:*:**:****.******::::.** : : *. ::. .*:.. .*::. * ::**** . : : * . .: ::* . .. .. : *****: : ::*:* ** **::**: : *: * : ", "identical_positions": 81, "similar_positions": 122, "identity": "21.04%" }, { "cls_id": "homologset.agr.RGD:620821", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70541-1", "uniprot_id": "EI2BG_RAT", "id": "P70541-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MEFQAVVMAVGG-------------------------GSRMTDLTS----------------SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTKDVQKALCAEFK-------------------------MKLKPDIVCIPDEADMGTADSLRHIYPKLKTDVLVLGCDLITDVALHEVVDLFR-AYDASLAMLMR-KGQESTEPVPGQKGKKKTVEQRDFIGVDSTGKR-----LLFMANEADLDEELVIKGSILQKHPRIHFQTGLVDAHLYCLKKYVVDFLMENKSITSIRSELIPYLVRKQFSSASSQQRQEDKEED--LKKKEPKSLDIYSFIKKDNTLTLAPYDACWNAFRRDKWEDLSRSQVRCY--------VHIMKEGLCSRVSTLGLYMEANRQVPKLLSVLCPEESMIHPSAQIANKHLIGADSLIGSDTQVGEKSSIKRSVIGSSCVIRDRVTVTNCLLMNSVTVEEGSSIHGSVICNNAVVEAGAEIRDCLIGSGQRIEAK----AKRMNEVIVGNDQLMEI----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AUN2-1", "uniprot_id": "B1AUN2_MOUSE", "id": "B1AUN2-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MEFQAVVMAVGG-------------------------GSRMTDLTS----------------SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTKDVQKALCAEFK-------------------------MKMKLDIVCIPDEADMGTADSLRHIYPKLKTDVLVLSCDLITDVALHEVVDLFR-AYDASLAMLMR-KGQESIEPVPGQKGKKKPVEQRDFIGVDSTGKR-----LLFMANEADLDEELVIKGSILQKHPRIHFHTGLVDAHLYCLKKYVVDFLMENRSITSIRSELIPYLVRKQFSSASSQQRQEDKEED--LKKKELKSLDIYSFIKKDDTLTLAPYDACWNAFRGDKWEDLSRSQVRCY--------VHIMKEGLCSRVSTLGLYMEANRQVPKLLSVLCPEESMIHSSAQIVNKHLIGADSLIGPDTQIGEKSSIKHSVIGSSCVIRDRTSITNCLLMNSVTVEEGSSIHGSVICNNAVIETGAEIKNCLVGSGQRIEAK----AKRMNEVIVGNDQLMEI----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NR50-1", "uniprot_id": "EI2BG_HUMAN", "id": "Q9NR50-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MEFQAVVMAVGG-------------------------GSRMTDLTS----------------SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKALCAEFK-------------------------MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLFR-AYDASLAMLMR-KGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKR-----LLFMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSASSQQGQEEKEED--LKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRCY--------VHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAK----AKRVNEVIVGNDQLMEI----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZA22-1", "uniprot_id": "A1ZA22_DROME", "id": "A1ZA22-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "MTEFQAVVFAAGR-------------------------GTRLPEVLG----------------DAPKCLLPVGPYPLIWYPLNLLQQHNFTEVIVVVLEQEKLEIQSALENTP----------------------LKLRLDYATIPSDGDFGTADSLRYIYDKIKSDFLVVSCDLVSNVSLYPLINKFR-EHDAALAMLLFPSGFESDVVMPGPKSKHK--PERDLIGIHAATQR-----LAFVSAASDCEETLNIQRHLLKNRGRLDVYSRLVDAHVYVLKKWVIDYLRRKENISTFKGEFLPHLIKKQHSKRPPKTVQDTTSEVGVVTKNEDHVLHYVGHTILDQKITQT---SLFNQSLSQ--SPYHGDIVRCYG-------IQAPRDAIGVRVNNTLSFLAINRKLASIWNNLCGEKHPLISPGAVVKSTQT-KEIIAADNAKLSEKTSLNFSVFGPNCIISPKNIVANSLIMSNAIVEEGCNIDNCIIGHRAQVKSGSVLKNCIIGPNYVVEEG----THSQAVHLSNADQFMEIDIQ-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09032-1", "uniprot_id": "EI2BG_YEAST", "id": "P09032-1", "name": "Translation initiation factor eIF2B subunit gamma", "aln": "-MSIQAFVFCGKGSNLAPFTQPDFPFQTQNKDSTAATSGDKLNELVNSALDSTVINEFMQHSTRLPKALLPIGNRPMIEYVLDWCDQADFKEISVVAPVDEIELIESGLTSFLSLRKQQFELIYKALSNSNHSHHLQDPKKINFIPSKANSTGESLQKELLPRINGDFVILPCDFVTDIPPQVLVDQFRNRDDNNLAMTIYYKNSLDSSIDKKQQQKQKQQQFFTVYSENEDSERQPILLDVYSQRDVTKTKYLQIRSHLLWNYPNLTVSTKLLNSFIYFCSFELCQLLKLGPQSMSRQASFKDPFTGNQQQQNPPTTDDDEDRNHD-DDDDYKPSATSIQPTYFKKKNDLILDPINCNKSLSKVFRDLSRRSWQHSKPREPIGIFILPNETLFIRANNLNAYMDANRFVLKIKSQTMFTKNIQIQSAAIG------ADAIVDPKCQISAHSNVKMSVLGTQANIGSRCRVAGSLLFPGVHLGDEVILENCIIGPMAKIGSKCKLSNCYIEGHYVVEPKNNFKGETLANVYLDEDEEDELIYDDSVIAGESEIAEETDSDDRSDEDSDDSEYTDEYEYEDDGLFER", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:**.*:. * :: :: . ** ***:* *:* * *: :: .* *: **. : : : : :: . **...: . : : ::: *.::: **:::::. ::: ** * *** : .. . : *:* . . . :* : : * *: :* : .: . : *:::.:* . : : * . : :..: : :* .. .. :: : .. .. * . : . .: : *... :: ** : .: . : .. : : : . ::. ::.:: **:*... * : ::..*:: .. : : :...:* * : . : :* : :* . . *: *: ", "identical_positions": 54, "similar_positions": 154, "identity": "9.22%" }, { "cls_id": "homologset.agr.RGD:620822", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54888-1", "uniprot_id": "RPA2_RAT", "id": "O54888-1", "name": "DNA-directed RNA polymerase I subunit RPA2", "aln": "-MDVDSRWRNLPSGPSLKHLTDPSYAVPPEQQK---AALQDLTRAHVDSFNYAVLEGLS-----------------HAVQAIPPFEFAFK---DERISLTIVDAAISPPAVPKGTI-CKELNIYPAECRGRRSTYRGKLTADISWAVN-GVPKGIIKQFLGXVPIMVKSKLCNLYNLPPQVLIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMIRPKWKSRGLGYTQFGVSIHCVREEHSAVNMNLHYVENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEEDSFFKNSVSQMLRIVMEEGCHTQ--KQVLDYLGERFRVKL-SLPDWYPNAEAAEFLFNQCICIHLKSN--TDKFYLLCLMTRKLFALARGECMEDNPDSLVNQEVLTPGQLFLMFLKEKMENWLLSIKIALDKRAQKTNVSINNEN---LMKIFSMGTELTRPFEYLLATGNLRSKTGLGFMQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTTVRKLLPESWGFLCPVHTPDGAPCGLLNHLTAVCEVVTK--FVYTASIPALLCGLGVTPVDAAPCRPYSDCYPVLLDGVMVGWVDKELAPEVADTLRRFKVLRER-RCSSLDGGGPDSHDRKAKPVPRAVPLHHSLQAGEACAEPGAGQRRARWNYGAALHEHCHLRGRGFWWSFHTPGALPSQPAEVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSPLVRPCMYDHYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFIDLSEKFKQGD---DSLVFGVKPGDPRVMQKLDNDGLPFIGAKLEFGDPYYGYLNLNTGEGFVVYYKSKENCVVDNIKVCSNDTG-SGKFKCVCVTVRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMMPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGMELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDKVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWS-AMRNRKYNCTVCGRS-------------------------------DSIDTVSVPYVFRYFVAELAAMNIKVKLDVI--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70700-1", "uniprot_id": "RPA2_MOUSE", "id": "P70700-1", "name": "DNA-directed RNA polymerase I subunit RPA2", "aln": "-MDVDGRWRNLPSGPSLKHLTDPSYGIPPEQQK---AALQDLTRAHVDSFNYAALEGLS-----------------HAVQAIPPFEFAFK---DERISLTIVDAVISPPSVPKGTI-CKDLNVYPAECRGRKSTYRGRLTADISWAVN-GVPKGIIKQFLGYVPIMVKSKLCNLYNLPPRVLIEHHEEAEEMGGYFIINGIEKVIRMLIVPRRNFPIAMVRPKWKSRGLGYTQFGVSMRCVREEHSAVNMNLHYVENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEEDSFFRNSVSQMLRIVIEEGCHSQ--KQVLNYLGECFRVKL-SLPDWYPNVEAAEFLLNQCICIHLQSN--TDKFYLLCLMTRKLFALARGECMDDNPDSLVNQEVLSPGQLFLMFLKEKMENWLVSIKIVLDKRAQKANVSINNEN---LMKIFSMGTELTRPFEYLLATGNLRSKTGLGFLQDSGLCVVADKLNFLRYLSHFRCVHRGAAFAKMRTTTVRRLLPESWGFLCPVHTPDGAPCGLLNHLTAVCEVVTK--FVYTASIPALLCGLGVTPVDTAPCRPYSDCYPVLLDGVMVGWVDKDLAPEVADTLRRFKVLREK-RIPPWMEVALIPMTGKPSLYPGLFLFTTPCRLVRPVQNLELGREELIGTMEQLFMNVAIFEDEVFGGISTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQNRSDNKLYRLQTPQSPLVRPCMYDFYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFIDLSEKFKQGE---DNLVFGVKPGDPRVMQKLDDDGLPFIGAKLEYGDPYYSYLNLNTGEGFVVYYKSKENCVVDNIKVCSNDMG-SGKFKCICITVRIPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMMPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGMELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDKVTNQPLGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHMCVECGSLLSPLLEKPPPSWS-AMRNRKYNCTVCGRS-------------------------------DTIDTVSVPYVFRYFVAELAAMNIKVKLDVI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9Y6-1", "uniprot_id": "RPA2_HUMAN", "id": "Q9H9Y6-1", "name": "DNA-directed RNA polymerase I subunit RPA2", "aln": "-MDPGSRWRNLPSGPSLKHLTDPSYGIPREQQK---AALQELTRAHVESFNYAVHEGLG-----------------LAVQAIPPFEFAFK---DERISFTILDAVISPPTVPKGTI-CKEANVYPAECRGRRSTYRGKLTADINWAVN-GISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQ--KQVLNYLGECFRVKL-NVPDWYPNEQAAEFLFNQCICIHLKSN--TEKFYMLCLMTRKLFALAKGECMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDN---LMRIFTMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQ--FVYTASIPALLCNLGVTPIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREK-RIPPWMEVVLIPMTGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFIDLSEKIKQGD---SSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMYYKSKENCVVDNIKVCSNDTG-SGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWS-AMRNRKYNCTLCSRS-------------------------------DTIDTVSVPYVFRYFVAELAAMNIKVKLDVV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20028-1", "uniprot_id": "RPA2_DROME", "id": "P20028-1", "name": "DNA-directed RNA polymerase I subunit RPA2", "aln": "MLEEMQQMKTIP----VLTNSRPEFKQIPKKLS---RHLANLGGPHVDSFDEMLTVGLDN----------------SAKHMIPNHWLSPA---GEKISMKVESIWIAKPKVPQDVIDVRTREIYPTDSRQLHVSYSGMCSVRLGWSVN-GVQKTPINMDLGEVPIMLRSKACNLGQATPEEMVKHGEHDSEWGGIFVIRGNEKIVRMLIMTRRNHPICVKRSSWKDRGQNFSDLGMLVQTVREDESSLSNVVHYLNNGTAKFMFSHVKRLSYVPVCLILKCLMDYTDEEIYNRLVQGYESDQYYVSCVQAMLREVQNENVYTH--AQCKSFIGNLFRARFPEVPEWQPDDDVTDFILRERVMIHLDTY--EDKFQLIVFMIQKLFQCAQGKYKVENVDSAMMQEVLLPGHLYQKYLSERVESWVSQVRRCLQKKLTSPDALVTSAV---MTQCMRQAGGVGRAIESFLATGNIASRTGLGLMQNSGLVIMAENINRMRYMSHFRAIHRGSYFTTMRTTEARQLLPDAWGFICPVHTPDGTPCGLLNHLTLTCEISMRPDPKLVKAIPKHLIDMGMMPLSNRRYLG-EKLYVVFLDGKHLGHIHQSEAEKIVDELRYGKIFG---TLPQMMEIGFIPFK-KNGQFPGLYIATGPARMMRPVWNLKWKRVEYIGTLEQLYMEIAIDAKEMYPDFTTHLELAKTHFMSNLANLIPMPDYNQSPRNMYQCQMGKQTMGTPCLNWPKQAANKLYRLQTPGTPLFRPVHYDNIQLDDFAMGTNAIVAVISYTGYDMEDAMIINKAAYERGFAYGSIYKTKFLTLDKKSS---------YFARHPHMPELIKHLDTDGLPHPGSKLSYGSPLYCYFDGEVATYKVVKMDEKEDCIVESIRQLGSFDL-SPK-KMVAITLRVPRPATIGDKFASRAGQKGICSQKYPAEDLPFTESGLIPDIVFNPHGFPSRMTIAMMIETMAGKGAAIHGNVYDATPFRFSEENTAIDYFGKMLEAGGYNYYGTERLYSGVDGREMTADIFFGVVHYQRLRHMVFDKWQVRSTGAVEARTHQPIKGRKRGGGVRFGEMERDALISHGAAFLLQDRLFHNSDKTHTLVCHKCGSILAPLQRIVKRNETGGLSSQPDTCRLCGDN-------------------------------SSVSMIEIPFSFKYLVTELSSVNINARFKLNEI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22138-1", "uniprot_id": "RPA2_YEAST", "id": "P22138-1", "name": "DNA-directed RNA polymerase I subunit RPA135", "aln": "-MSKVIKPPGQARTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFN-ALTEGPDGGLLNLGVKDIGEKVIFDGKPLNSEDEISNSGYLGNKLSVSVEQVSIAKPMSNDGVSSAVERKVYPSESRQRLTSYRGKLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKMSPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPMAIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLNDGQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGNDVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFRVVFQASPDQ-SDLEVGQEVLDRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKEKIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHFAHKCRISTQ--QSDVSRIPSILYSLGVAPASHTFAAG-PSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEGKTPGLPIDLEIGYVPPS-TRGQYPGLYLFGGHSRMLRPVRYLPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTNILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCHRSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAVISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALNRNRGDPITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICAYFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQTVSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSETGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQDSTPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGEELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPVKGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKKLLTKSEDGEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDSELSAMGIRLRYNVEPK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . . . : . * : .*: **: * . . . :: .:::*..: . *: * ... ::**::.* :* * : *:** * : * :*:*::*: *:* : .* :::* *. .* ** *::.* **::****: ***.*:.: *..: ** .::. *: :: ** :.:: . :**:::* . : * *. :*: : **.* :* :*:: :: . .*.: . :. :** . :. : * .::*: **. : *: .: :. : :: . : :** . :** :: :* :**: . *: :* *: **** * *: *.*::: :: .: . . . : : :: :::***: *::**.: * ** ::*:::* *::**** :***: *: ::** .*:***::***:******** ****:**:: *.: : . ** * .:*: * . . * :** :* : :. . :.* ** *: . . . * : .. : : . . . :**: *:.*.****************** * : .:: ******** :*:.:. ** :*::. * **:***********:****:**:: ****.:*::**:: : * : . *. . . :::** ****. *: :. *.* *:: : ...* . ::.:. .. : : :.:. *: * . *****:** ****: *: :*: *:**:*:*: ***::***.*******.*::*::***..*:** *:**: *.*:::. :***: * .***::*.* :*** * *: ***:.***:******** **:***:**. : * **: **: **:*.********:.**::***:***:: ** : : :* :***:*:. . : : . . . . . : :*: ::*: :**:::.*. : .: ", "identical_positions": 334, "similar_positions": 354, "identity": "27.6%" }, { "cls_id": "homologset.agr.RGD:620823", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02401-1", "uniprot_id": "LPH_RAT", "id": "Q02401-1", "name": "Lactase/phlorizin hydrolase", "aln": "MELPWTALFLSTVLLGLSCQGSDWESDRNFISAAGPLTNDLVLNLNYPPGKQGSDVVSGNTDHLLCQQPLPSFLSQYFSSLRASQVTHYKVLLSWAQLLPTGSSKNPDQEAVQCYRQLLQSLKDAQLEPMVVLCHQTPPTSSAIQREGAFADLFADYATLAFQSFGDLVEIWFTFSDLEKVIMDLPHKDLKASALQTLSNAHRRAFEIYHRKFSSQGGKLSVVLKAEDIPELLPDPALAALVQGSVDFLSLDLSYECQSVATLPQKLSELQNLEPKVKVFIYTLKLEDCPATGTSPSSLLISLLEAINKDQIQTVGFDVNAFLSCTSNSEESPSCSLTDS-LALQTEQQQETAVP-SSPGSAYQRVWAAFANQSREERDAFLQDVFPEGFLWGISTGAFNVEGGWAEGGRGPSIWDHYGNLNAAEGQATAKVASDSYHKPASDVALLRGIRAQVYKFSISWSGLFPLGQKSTPNRQGVAYYNKLIDRLLDSHIEPMATLFHWDLPQALQEQGGWQNESVVEAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHAPAISDPGMASFKVAHLILKAHARTWHLYDLHHRLQQQGRVGIVLNSDLAEPLDRKSPQDLAAAERFLHFMLGWFAHPIFVDGDYPTTS-AQIQHINQQCGHPLAQLPEFTEAEKRLLKGSADFLGLSHYTSRLISKAGRQTCTSSYDNIGGFSQHVDPEWPQTASPWIRVVPWGIRRLLRFASMEYTKGKLPIFLAGNGMPVGEEADLFDDSVRVNYFNWYINEVLKAVKEDLVDVRSYIVRSLIDGYEGPLGFSQRFGLYHVNFNDSSRPRTPRKSAYLFTSIIEKNGFSAKKVKRNPLPVRADFTSRARVTDSLPSEVPSKAKISVEKFSKQPRFERDLFYDGRFRDDFLWGVSSSPYQIEGGWNADGKGPSIWDNFTHTPGNGVKDNATGDVACDSYHQLDADLNILRTLKVKSYRFSISWSRIFPTGRNSTINKQGVDYYNRLIDSLVDNNIFPMVTLFHWDLPQALQDIGGWENPSLIELFDSYADYCFKTFGDRVKFWMTFNEPWCHVVLGYSSGIFPPSVQEPGWLPYKVSHIVIKAHARVYHTYDEKYRSEQKGVISLSLNTHWAEPKDPGLQRDVEAADRMLQFTMGWFAHPIFKNGDYPDVMKWTVGNRSELQHLASSRLPTFTEEEKNYVRGTADVFCHNTYTSVFVQHSTPRLNPPSYDDDMELKLIEMNSS--TGVMHQDVPWGTRRLLNWIKEEYGNIPIYITENGQGLENPTLDDTERIFYHKTYINEALKAYKLDGVDLRGYSAWTLMDDFEWLLGYTMRFGLYYVDFNHVSRPRTARASARYYPDLIANNGMPLAREDEFLYGEFPKGFIWSAASASYQVEGAWRADGKGLSIWDTFSHT-PLRIGNDDNGDVACDSYHKIAEDVVALQNLGVSHYRFSIAWSRILPDGTTKFINEAGLSYYVRFIDALLAAGITPQVTIYHWDLPQALQDVGGWENETIVQRFKEYADVLFQRLGDRVKFWITLNEPFVIAAQGYGTGVSAPGISFRPGTAPYIAGHNLIKAHAEAWHLYNDVYRARQGGTISITISSDWGEPRDPTNREHVEAARSYVQFMGGWFAHPIF-KNGDYPEVMKTRIRDRSLGAGLNK-SRLPEFTESEKSRIKGTFDFFGFNHNTTVLAYNLDYPAA----FSSFDADRGVA-SIADSSWPVSGSFWLKVTPFGFRRILNWLKEEYNNPPIYVTENGVSRRGEPELNDTDRIYYLRSYINEALKAVHDKVDLRGYTVWSIMDNFEWATGFAERFGVHFVNRSDPSLPRIPRASAKFYATIVRCNGFPDPAQGPHPCLQQPEDAAPTASPVQS-EVPFLGLMLGIAEAQTA-LYVLFALLLLGACSLAFLTYNTGRRSKQGNAQPSQHQLSPISSF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VPT3-1", "uniprot_id": "F8VPT3_MOUSE", "id": "F8VPT3-1", "name": "Lactase/phlorizin hydrolase", "aln": "MELPWTALFLSTFLLGLSCQGNDWESDRNFISAAGPLTNDLVHNLNHPLGKQGSDLVAGDTDIYVCQQPLPSFLPQYFSSLRASQVTHYKVLLSWAQLLPKGSSKNPDQEAVQCYRQLLQSLKDAQLQPMVVLFHQMPPTS-TIQRDGGFADLFADYATLAFQSFGDLVEIWFTFSDLEKVIMGLPHQHLKASGLQTLSDAHRKAFDVYHRKYSSQGGKLSVVLKAEDLPKLLPDPSSAALVKGSVDFLSLDLSYDCQSISTLPQKLSELQNLEPKVKVFVYTLKPQDCPSTGMSPASLLFRLLEAINKDQVQTVGFDVSAFLSCTSSSEESPSCSLTYSSLALQSEQQHETVVS-SFPGSAYQRVWAALANQSREERDAFLQDVFPEGFLWGVSTGAFNVEGGWAEGGRGPSIWDHYSNLNAAESQATAKVASDSYHKPVSDVALLRGLRADVYKFSISWSRIFPFGQRTSPNLQGVAYYNKLIDSLLDSQVEPMATLFHWDLPQALQEQGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVISYAGYGTGQHAPAISDPGVASFKVAHLILKAHARTWHHYNYHHRQKQQGRVGIVLNSDWAEPLDGKSPQDLAAAERYLHFMLGWFAHPIFIDGDYPAALRAQIQHTNQQCGRPLAQLPEFTEAEKRLLKGSADFLGLSHYTSRLISKAGQQTCIPSYDNIGGFSQHVDPKWPQTASPWIRVVPWGIRRLLRFASLEYTKGKLPIFLAGNGMPIGEGSDLFDDSMRVNYLNLYINEVLKAVKEDSVDVRSYIARSLIDGYEGPLGYSQRFGLYHVNFNDSSRPRTPRKSAYFFTSIIEKNGFPAKKVKRNPLPLKADFSSRARAAFSFPSEVPSKAKVVWEKFSRQPKFERDLFYHGTFRDDFLWGVSSSAYQIEGGWDADGKGPSIWDNFTHTPGNGVKDNATGDIACDSYHQLDADINILRTLKVKSYRFSISWPRIFPTGRNSSINKQGVDYYNKLIDRLLESNIFPMVTLFHWDLPQALQDIGGWENPSLIELFDSYADFCFKTFGDRVKFWMTFNEPWCSAVLGYSSGIFPPNVQDPGSLSYKVSHVIIKAHARVYHTYDEKYRQEQKGVISLSLNTHWVEPKDPGVQRDVEAADRMLQFNLGWFAHPIFKNGDYPDVMKWNVGNRSELQHLASSRLPSFTEEEKNYIRGTADVFCINTYTSVFAQHVTPRLNPPSYDNDMELKASDMNSSALISMMHQDVPWGMRRLLNWIKEEYGNIPIYITENGQGLTNPTLDDTERIFYHKTYINEALKAYRLDGVDLRGYSAWALMDNFEWLHGYTMRFGLYHVDFDHVNRPRTARASARYYTEVITNNGMPLAKEDEFLYGEFPKGFIWSAASASYQVEGAWRADGKGLSIWDTFSHT-PLKIGNDDNGDVACDSYHKIAEDVVALQNLGVSHYRFSISWPRILPDGTTKFINEAGLNYYVRFIDALLAAGITPQVTMYHWDLPQALQDVGGWENETVVQRFKDYADVLFRRLGDKVKFWITLNEPFVIAAHGYGSGVSAPGISFRPGTAPYTAGHNLIKAHAEAWHLYNSTYRNSQGGVISITISSDWAEPRDPSNQEDVEAARRYVQFMGGWFAHPIF-KNGDYPEVMKTRIRDRSLAAGLNK-SRLPEFTESEKKKIQGTFDFFGFNHYTTVLAYNLNYAAA----VSSFDADRGVA-SITDRSWPDSGSFWLKMTPFGFRRILNWLKEEYNNPLIYVTENGVSRRGDPELNDTDRIYYLRSYINEALKAVRDKVDLRGYTVWSIMDNFEWATGFAERFGVHFVNRSDPSLPRIPKASAKVYASIVRCNGFPDPAQGPHPCLQQPEDAGPTASPVKS-EVPFLGLMLGTAEAQTA-LYVLFALVLLGVCSVAFLLYKYCKRSKQGTTQPGHHGLSQISSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09848-1", "uniprot_id": "LPH_HUMAN", "id": "P09848-1", "name": "Lactase/phlorizin hydrolase", "aln": "MELSWHVVFIA--LLSFSCWGSDWESDRNFISTAGPLTNDLLHNLSGLLGDQSSNFVAGDKDMYVCHQPLPTFLPEYFSSLHASQITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPAS-TLRRTEAFADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQLQTLSDAHRKAYEIYHESYAFQGGKLSVVLRAEDIPELLLEPPISALAQDTVDFLSLDLSYECQNEASLRQKLSKLQTIEPKVKVFIFNLKLPDCPSTMKNPASLLFSLFEAINKDQVLTIGFDINEFLSCSSSSKKSMSCSLTGS-LALQPDQQQDHETTDSSPASAYQRIWEAFANQSRAERDAFLQDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTTEGQATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPGISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGIVLNSDWAEPLSPERPEDLRASERFLHFMLGWFAHPVFVDGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQHVNHVWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSIIEKNGFLTKGAKRLLPPNTVNLPSKVR-AFTFPSEVPSKAKVVWEKFSSQPKFERDLFYHGTFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDPGWAPYRIAHAVIKAHARVYHTYDEKYRQEQKGVISLSLSTHWAEPKSPGVPRDVEAADRMLQFSLGWFAHPIFRNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYEDDQEMAE-EEDPSWPSTAMNRAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGMPLAREDEFLYGRFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPGVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSDWAEPRDPSNQEDVEAARRYVQFMGGWFAHPIF-KNGDYNEVMKTRIRDRSLAAGLNK-SRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATA----ISSFDADRGVA-SIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVRCNGFPDPATGPHACLHQP-DAGPTISPVRQEEVQFLGLMLGTTEAQTA-LYVLFSLVLLGVCGLAFLSYKYCKRSKQGKTQRSQQELSPVSSF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VV98-1", "uniprot_id": "Q9VV98_DROME", "id": "Q9VV98-1", "name": "Cytosolic beta-glucosidase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMQIILPLFVLTASCLGSPVSQTR-----RFPNDFLWGVGSSSYQIEGGWNADDKGESIWDFLTHTHPEKIVDRSNGDVSADSYHQWKRDVQMVKELHVGTYRFSLSWPRIMPGGYMNHVSTAGIKYYSNLIDELLRYNITPMVTIYHWELPQKLQELGGWTNPEIIPLFKDYARLVLEMYGDRVKIWTTVNEPWHVCEHGYGVDYMAPSYN-YPGIPAYLCGHNLLKAHAEVVHMYRELFQPRQGGRMGITLDTSWPEPRDPNSAEDREASERAMQFYVGWFGHPIFSKHGNYPKVMIERIRNLSKEQGFGARSRLPEFTTEEIHRIRGTSDFFGINSYTSNLVTSNGHNNTGKFPVPSFNHDMGVVESQEGVDWPGSGSVWLKVYPKGMYNLLMWIHREYNAPEIIVTENGVSDRG--GLEDYARVDYYNLYLSAVLDAMEDGANISGYIAWSLMDSYEWKAGFSEKFGLYHVDFNSPQRTRTPKISARVFAQLCKTN-----------------TIDWSYRPKLDEEQQLVAMAQLPAEARTSGASGAVSWSLMGILLLALLR-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * *::: .**:.*:*...*::**:**.*.**.** **** ::** * :: : ***:.****: .*: :::* *. ****::*.**:*.* ..:. **:.** .:** ** .* * **:***:*** **::*** * :: **:** :::. **:**:* *:***: :. :*** . **. . ** ..* ****:*****. *:*.. :: *** :.**:.:.* *****.. *. **:. :** ***.**** *:*:* :** ***: * *:. ******* .* :*.** ****:* *: *. . .: : ..**: * **. * . .** ***.***: * *: .:* *::.*** * * ******* * *:* *: * . *:. .*.*:.* .:: ** .** **.:** :**:*:**::.*: ..*. .* *: **:.:* : : * : * . * ::.: :**:*: .: *:* :*:* ", "identical_positions": 218, "similar_positions": 166, "identity": "11.22%" }, { "cls_id": "homologset.agr.RGD:620824", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54889-1", "uniprot_id": "RPA1_RAT", "id": "O54889-1", "name": "DNA-directed RNA polymerase I subunit RPA1", "aln": "MLASKHTPWRRLQG-ISFGMYSAEELKKLSVKSITNPRYVDSLGNPSADGLYDLALGPAD-SKEVCSTCVQDFNNCSGHLGHIDLPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAAIHLLVCQLKVLDVGALQAVYELERILS-----------RFLEET---------------SDPSAFEIQEELEEYTSKILQNNLLG----SQGAHVKNVCESRSKLVAHFWKTHMA--AKRCPHCKTGRSVVRKEHNSKLTITYP----------------------AMVHKKSGQKDAELPEGAPAAPGIDEAQMGKRG--YLTPSSAQEHLFAIWKNEGFFLNYLFSGL----DDIGPESSFNPSMFFLDFIVVPPSRYRPINRLGDQMFTNGQTVNLQAVMKDAVLIRKLLAVMAQEQKLPCEMTEITIDKENDSSGAIDRSFLSLLPGQSLTDKLYNIWIRLQSHVNIVFDSDMDKLMLEKYP---GIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRTALSAVDATQREAVAKQLLTPSTGIPKPQGAKVVCRHVKNGDILLLNRQPTLHRPSIQAHRAHILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGANMTIRGCFFTREQYMELVYRGLT-----DKVGRVKLFPPAILKPFPLWTGKQVVSTLLINIIPEDYTPLNLTGKAKIGSKAWVKEKPRP-VPDFDPD--SMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGRVLTCLARLFTAYLQLYRGFTLGVEDILVKPNADVMRQRIIEESTQCGPRAVRAALNLPEAASCDEIQGKWQDAIWRKDQRDFNMIDMKFKEEVNHYSNEINKACMPFGLHRQFPENNLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIRPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVIQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFLQPKQFP-FLASNYEVIMKSKHLHEVLSRADPQKVLRHFRAIKKWHHRHSSALLRKGAFLSFSQKIQAAVKALN-LEGKTQNGRSPETQQMLQMWHELDEQSRRKYQKRAAPCPDPSLSVWRPDIHFASVSETFEKKIDDYSQEWAAQAEKSHNRSELSLDRLRTLLQLKWQRSLCDPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVFNTKKALRRVKSLKKQLTRVCLGEVLQKVDIQESFCMG--EKQNKFRVYELRFQFLPHAYYQQEKCLRPEDILHFMETRFFKLLMEAIKKKNSKASAFRSVNTRRATQKDLDDTEDSGRNRREEERDEEEEGNIVDAEAEEGDADASDTKRKEKQEEEVDYESEEE----GEEEEEEDVQEEENIKGEGAHQTHEPDEEEGSGLEEE-------SSQNPPCRHSRPQGAEAMERRIQAVRESHS-FIEDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHNAIVYTTKGITRCLLNETINSKNEKEFVLNTEGINLPELFKYSEVLDLRRLYSNDIHAVANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIQSSSSPLQQMTFETSFQFLKQATMMGSHDELKSPSACLVVGKVVKGGTGLFELKQPLR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35134-1", "uniprot_id": "RPA1_MOUSE", "id": "O35134-1", "name": "DNA-directed RNA polymerase I subunit RPA1", "aln": "MLASKHTPWRRLQG-ISFGMYSAEELKKLSVKSITNPRYVDYLGNPSANGLYDLALGPAD-SKEVCATCVQDFNNCSGHLGHIDLPLTVYNPFLFDKLYLLLRGSCLSCHMLTCPRAAIYLLISQLRVLEVGALQAVYELERILS-----------RFLEET---------------GDPSAFEIQEELEEYTSKILQNNLLG----SQGTHVKNVCESRSKLVAQFWKTHMA--AKQCPHCKTGRSVVRKEHNSKLIITYP----------------------ATVHKKSDQEGTELPEGVPEAPGIDKAQMGKRG--YLTPSSAQEHLFAIWKNEGFFLNYLFSGL----DDIGPESSFNPSMFFLDFIVVPPSRYRPVNRLGDQMFTNGQTVNLQAVMKDAVLIRKLLALMAQEQKLPCEMTELTIDKENDSSVAIDRSFLGLLPGPSLTDKLYNIWIRLQSHVNIVFDSEMDKLMLEKYP---GIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRTALSSVDAAQREAVAKQLLTPATGAPKPQGTKVVCRHVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGANMTIRGCFFTREQYMELVYRGLT-----DKVGRVKLFPPAILKPFPLWTGKQVVSTLLINIIPEDYAPLNLSGKAKIGSKAWVKEKPRP-IPDFDPD--SMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGRVLTCLARLFTAYLQLYRGFTLGVEDILVKPNADVVRQRIIEESTQCGPQAVKAALSLPETASCDEIQGKWQDAHLSKDQRDFNMIDMKFKEEVNHYSNEINKACMPLGLHRQFPENNLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIRPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVIQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFLQPKQFP-FLAGNYEVIMKSKHLHEVLSRADPQKVLGHIKAIKKWHHKHSGALLRKGAFLSFSQKIQAAVKALN-LKGSIQNGRSPETQQMLQMWYDLDEESRWKYQKRAAPCPDPSLSVWRPDIYFASVSETFEKKIDDFSQEWAAQAERSYKKSELSLDRLRTLLQLKWQRSLCDPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVFDTKKALKKVKSLKKRLTRVCLGEVLQKVDIQESFCMG--EKRNKFQVYELRFQFLPHAYYQQEKCLRPEDILHFMETRFFKLLMEAIKKKKNKASAFRNVNSRRATQKDLNDTEDSGRSQREEERDEEEEGNIVDAEAEEGDADASDTKRKEKQEEEVDYESEEE----GEEEEEEEVQEEGNIKGDGVHQGHEPDEEEHLGLEEEE------SSQKPPRRHSRPQGAEAIKRRIQAVRESYS-FIEDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHKAIVYTTKGITRCLLNETTNSKNEKELVLNTEGINLPELFKYSEILDLRRLYSNDIHAMANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIQSSSSPLQQMTFETSFQFLKQATMMGSHDELKSPSACLVVGKVVKGGTGLFELKQPLR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95602-1", "uniprot_id": "RPA1_HUMAN", "id": "O95602-1", "name": "DNA-directed RNA polymerase I subunit RPA1", "aln": "MLISKNMPWRRLQG-ISFGMYSAEELKKLSVKSITNPRYLDSLGNPSANGLYDLALGPAD-SKEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAVIHLLLCQLRVLEVGALQAVYELERILN-----------RFLEEN---------------PDPSASEIREELEQYTTEIVQNNLLG----SQGAHVKNVCESKSKLIALFWKAHMN--AKRCPHCKTGRSVVRKEHNSKLTITFP----------------------AMVHRTAGQKDSEP-------LGIEEAQIGKRG--YLTPTSAREHLSALWKNEGFFLNYLFSGM----DDDGMESRFNPSVFFLDFLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKLPEEVATPTTDEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKLMMDKYP---GIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCRHVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRGLT-----DKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKETPRS-VPGFNPD--SMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGKVLTCLARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYDEVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIKPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFLQPKQFP-FLASNYEVIMKSQHLHEVLSRADPKKALHHFRAIKKWQSKHPNTLLRRGAFLSYSQKIQEAVKALK-LESENRNGRSPGTQEMLRMWYELDEESRRKYQKKAAACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCME--EKQNKFQVYQLRFQFLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVREIHP-FIDDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHGAVIYATKGITRCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIRSNSSPLQQMTFETSFQFLKQATMLGSHDELRSPSACLVVGKVVRGGTGLFELKQPLR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P91875-1", "uniprot_id": "RPA1_DROME", "id": "P91875-1", "name": "DNA-directed RNA polymerase I subunit A", "aln": "MGSKRAMDVHMFPSDLEFAVFTDQEIRKLSVVKVITGITFDALGHAIPGGLYDIRMGSYGRCMDPCGTCLK-LQDCPGHMGHIELGTPVYNPFFIKFVQRLLCIFCLHCYKLQMKDHECEIIMLQLRLIDAGYIIEAQELELFKS-----------EIVCQN---------------TEN-LVAIKNGDMVHPHIAAMYKLLE----KNEKNSSNSTKTSCSLRTAITHSALQRLGKKCRHCNKSMRFVRYMHRRLVFYVTL----------------------ADIKER---------------VGTGAETGGQNK--VIFADECRRYLRQIYANYPELLKLLVPVLGLSNTDLTQGDRSPVDLFFMDTLPVTPPRARPLNMVGDMLKGNPQTDIYINIIENNHVLNVVLKYMKGGQ---------------EKLTEEAKAAYQTLKGETAHEKLYTAWLALQMSVDVLLDVNMSREMKSGE----GLKQIIEKKSGLIRSHMMGKRVNYAARTVITPDPNINVDEIGIPDIFAKKLSYPVPVTEWNVTELRKMVMNGPDVHPGANYIQDKNGFTTYIPADNASKRESLAKLLLSNPK-----DGIKIVHRHVLNGDVLLLNRQPSLHKPSIMGHKARILHGEKTFRLHYSNCKAYNADFDGDEMNAHYPQSEVARAEAYNLVNVASNYLVPKDGTPLGGLIQDHVISGVKLSIRGRFFNREDYQQLVFQGLS-----QLKKDIKLLPPTILKPAVLWSGKQILSTIIINIIPEGYERINLDSFAKIAGKNWNVSRPRPPICGTNPEGNDLSESQVQIRNGELLVGVLDKQQYGATTYGLIHCMYELYGGDVSTLLLTAFTKVFTFFLQLEG-FTLGVKDILVTDVADRKRRKIIRECRNVGNSAVAAALELEDEPPHDELVEKMEAAYVK-DSKFRVLLDRKYKSLLDGYTNDINSTCLPRGLITKFPSNNLQLMVLSGAKGSMVNTMQISCLLGQIELEGKRPPLMISGKSLPSFTSFETSPKSGGFIDGRFMTGIQPQDFFFHCMAGREGLIDTAVKTSRSGYLQRCLIKHLEGLSVHYDLTVRDSDNSVVQFLYGEDGLDILKSKFFNDKFCADFLTQNATAILRPAQLQLMKDEEQLAKVQRHEKHIRSWEKKKPAKLR--AAFTHFSEELREEVEVKRPNEINSKTGRRRFDEGLLKLWKKADAEDKALYRKKYARCPDPTVAVYKQDLYYGSVSERTRKLITDYAKRKPALKET-----------IADIMRVKTIKSLAAPGEPVGLIAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMLASSNIKTPSMDIPIKPGQQ--HQAEKLRINLNSVTLANLLEYVHVSTGLTLD--PERS--YEYDMRFQFLPREVYKEDYGVRPKHIIKYMHQTFFKQLIRAILKVSNASRTTKIVVID--DKKDADKDDDNDLDNGDEVGRSKAKANDDDSSDDNDDDDATGVKLKQRKTDEKDYD------------DPDDVEELHDANDDDDEAEDEDDEEKGQDGNDND------------------GDDKAVER-----LLSND-MVKAYTYDKENHLWCQVKLNLSVRYQKPDLTSIIRELAGKSVVHQVQHIKRAIIYK----GNDDDQLLKTDGINIGEMFQHNKILDLNRLYSNDIHAIARTYGIEAASQVIVKEVSNVFKVYGITVDRRHLSLIADYMTFDGTFQPLSRKGMEHSSSPLQQMSFESSLQFLKSAAGFGRADELSSPSSRLMVGLPVRNGTGAFELLTKIC---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10964-1", "uniprot_id": "RPA1_YEAST", "id": "P10964-1", "name": "DNA-directed RNA polymerase I subunit RPA190", "aln": "MDISKPVGS-EITS-VDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFL--RNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLGSLNSSMYTDDEAIEDNEDEMDGEGSKQSKDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLS--RGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFIRQDMIKKQKQAKKLDGSNEASANDEESFDVGRNPTTRPKTGSTYILSTEVKNILDTVFRKEQCVLQYVFHSR----PNLSR-KLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLN----------------------DDLSKLQKDKVSLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGK---------------GSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATA-FTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFC---LDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHS----------------------------------------------------KEPHYKQSVKY-DPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKLFKSSDGVNE---KKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFHFAGHGAANVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSD-EQADTFCKSISKVLLSEVIDKVIVTETTGTSNTAGGNAARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRTTGPDIGVAVPRLQTDVANSSSNSKRLEEDNDEEQSHKKTKQAVSYDEPDEDEIETMREAEKSSD-------------EEGIDSDKESDSDSEDEDVDMNEQINKSIVEAN------------------NNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPE----PENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNAA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: : . :.*.: : :*:::**. .: . .* **:. ..****: :*. : *.** . *.** ***:* . ***:::. : * ** *: : :*:::: * : :*: : . : :. . ::. : * .. . . .* : : : :* :* .* : . :. * : : . . :. * :: : .*: :. : . . **:* : *.*.* * . :*: : * *. :: ::. : :. : .:* . :: :* *: .:* : . *::* :***.**:*.*******:****:** ** *:.:***:* :** **:** *** :*: ***: *:***: ***. : :::* . : . . :*:::*: **: .. * * **: * *::*:****:**:.*: .*:.::* **.:****:* ************ *:**.* .**** *. . .:**.*..* *: ******: :*. :: :. **.**.* : :: : : :.*:*:** **:***:::*:::*: * . :** . ** .: * . *.:* :::* ** *:*** :**:: **::*. :*:** :.: :*: : ::** :: ** *:.*: :. .: * *:. . . * *. . .* . .. *: . *.. ::* .. :: :.:: . *:* * :** *.:* *. ****** **. ** ***** ***:* *:* ***:**.* .:* . :**:: *** :**:* :::**********:***************: *:***: : ** ::**:*.::***:** *.:** * ..: * .::: : : .. : .. : : .:. ::. : : *: . ** :: :. : .**** . : .: .. . : : ::::* :** ***.**::*:**:****************:* ************:* **: **** * :*: . .:...: :. * *.:::: : : . * ::::*: . *.:: : :.: . : *:: * :* * . : . : . . .. : .:. . :. : : : * . : : ::. : . :. : :*: . : . : ::* :: * :* *. **:..::*. : : .:: .:. ::: * *.: : :: . :* *:*:*: ::. .:*: : ***: *: .***:*** ..* :*:.:** *.*:*. ***.*:** * :*.: .:.* *:. .:*.: :*::*:: ***..*. . ::* ***: ::** . *** *:: : ", "identical_positions": 431, "similar_positions": 513, "identity": "23.84%" }, { "cls_id": "homologset.agr.RGD:620825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59645-1", "uniprot_id": "FXYD3_RAT", "id": "P59645-1", "name": "FXYD domain-containing ion transport regulator 3", "aln": "MQEFALSLLVLLAGLPTLDANDPEDKDSPFYYDWHSLRVGGLICAGILCALGIIVLMSGKCKCKFSQKPSHRPGDGPPLITPGSAHNC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61835-1", "uniprot_id": "FXYD3_MOUSE", "id": "Q61835-1", "name": "FXYD domain-containing ion transport regulator 3", "aln": "MQEVVLSLLVLLAGLPTLDANDPENKNDPFYYDWYSLRVGGLICAGILCALGIIVLMSGKCKCKFRQKPSHRPGEGPPLITPGSAHNC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14802-1", "uniprot_id": "FXYD3_HUMAN", "id": "Q14802-1", "name": "FXYD domain-containing ion transport regulator 3", "aln": "MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:..*.***:***:*.***** *:*:.******:**:********:***:***::**.****** **..*:**: *********:. ", "identical_positions": 61, "similar_positions": 23, "identity": "69.32%" }, { "cls_id": "homologset.agr.RGD:620826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88884-1", "uniprot_id": "AKAP1_RAT", "id": "O88884-1", "name": "A-kinase anchor protein 1, mitochondrial", "aln": "MAIQFRSLFPLALPGMLALLGWWWFFSRKKDRLSSNGKQ-----VGTLKVGPAIEDRLPTEEACPGVLSVTPSVTQPPGKEEQRSMDRPLSDPPALPRTRQVRRRSESSGNLPSIVDTRLQAGQCSDENSKVVLSLMGDEAKSIPLGRPLF-PKDLSFPYEAVEGCKQESALGRTPGRGWL------SQCAASGENARETGGAEGTGDAVLGESVLEEGLLPQECVSEVEKSEFPILAPGGGGGEKVRSGPPQVDELLKKEEYIVGKLPSSFVGPVHSELVKDEGALVPQVKGSQ---DRSLARELDKDKTLPEKDQ----------------------------IEQTAFQIISQVILEATEEIRATTVGKTVAQVHPTPGTQPQGQEESCVPASQETSLGQEIPDPASTRTGATAS---------PSAGAPPPKTYVSCLSSPLSGPTKDQKPKNSAHHISLAPCPPPVTPQRQSLDGASNPRGDDTFVTCTSNNSQSVLSVTSLGLCSDPVSTSRLEDSCTETISSSGDKAVTPPLPDSTEPFSNGVLKEELSDLGTEDGWTMDTEADHSGGSDGNSMDSVDSCCGLTKPDSPQTVQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAP----PLPSLALPSLPMTSW---LMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVAS-YEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSATGLPLIQLWSVVG-DEVVLINRSLVERGLAQWVDSCYASL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08715-1", "uniprot_id": "AKAP1_MOUSE", "id": "O08715-1", "name": "A-kinase anchor protein 1, mitochondrial", "aln": "MAIQLRSLFPLALPGMLALLGWWWFFSRKKDRLSSSDKQ-----VETLKVGPAIKDRRLSEEACPGVLSVAPTVTQPPGREEQRCVDKPSTEPLALPRTRQVRRRSESSGNLPSVADTRSQPGPCRDEIAKVELSLMGDKAKSIPLGCPLL-PKDASFPYEAVERCKQESALGKTPGRGWP------SPYAASGEKARETGGTEGTGDAVLGENVSEEGLLSQECVSEVEKSEFPILAPGGGEGEEVSHGPPQVAELLKKEEYIVGKLPSSFVEPVHSEPVKDEDALEPQVKGSSNTSDRDLAGELDKDETVPENDQ----------------------------IKQAAFQLISQVILEATEEFRATTVGKTVAQVHPTSATQPKGKEESCVPASQETSLGQDTSDPASTRTGATAS---------PSAEALPPKTYVSCLSSPLSGPTKDQKPKNSAHHISLAPCPPPVTPQRQSLEGASNPRGDDNFVACMANNSQSVLSVSSLGQCSDPVSTSGLEDSCTETISSSGDKAMTPPLPVSTQPFSNGVLKEELSDLGTEDGWTMDTEADHSGGSDGNSMDSVDSCCGLTKPDSPQSVQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAP----PLPSLALPSLPMTSW---LMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVAS-YEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSATGLPLIQLWSVVG-DEVVLINRSLVERGLAQWVDSYYASL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92667-1", "uniprot_id": "AKAP1_HUMAN", "id": "Q92667-1", "name": "A-kinase anchor protein 1, mitochondrial", "aln": "MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKE-LSTVSKLPAEPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQPGYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSRFIESAHTELAKDDAAPAPPVADAKAQ-DRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEATEQVLATTVGKVAGRVCQASQLQGQ-KEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDSKPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPESTVPFSNGVLKGELSDLGAEDGWTMDAEADHSGGSDRNSMDSVDSCCSLKKTESFQNAQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQSVQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAP----PLPSLALPSLPMTSW---LMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVAS-YEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVMPLSDDDQFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWSVVG-DEVVLINRSLVERGLAQWVDSYYTSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KVW1-1", "uniprot_id": "Q7KVW1_DROME", "id": "Q7KVW1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------MTLPCRCCCCSG----KVTIFQYSAKMVSGRPLLYLSLPG-----------VAFILGVFWFRRRYKNCLDKP--------------------DDEDSSAINDSSIEPTVQARKANGVLQNGKLPQQSASKSMNINGTLVNGSGSGSGSSSDEKDSPTTMLYGKSAPIKIQSNGRTSNGKHQQQIDSEILKSKIQDAEHKTLCSIDEDFEN---------------------------------------------------------------------------------------------------------------------------LSSPRDLPDSVNTRVSFYNRKATQKTVEPVVIKATRTPKISPENSFLDTN------YTNKECEQNNN------------------------CEPKEEPSKKEADQEELEQDQE---QTVLKEEVVDSNGNQKRNVDAASPS------------LSICSVQSGDSGKGSSLPRSEATRVKTTYEFLFPISLIGHLYGRKRAFINQIKAKTLASVSVGKNPYSGKVRICTIEGTESEIDAALAMIRQRLPAKRYPNFTMQRIHFALPQTIVPLSTESLYNLQLKLIEGINNDVVVSAVLSGSHIFIQHPLHPSHPSLPLLQKQLYDSYSTMEAPLLPS-LELSAVCVIP-INDVWYRVQIVDTDPEDEERCVIKFLDFGGYMNVGFNTLRQIRTDFMNVPFQSTECILSNIEPIGG--TWSIEAAEILNKLTKGIVLQAQVAGYNSHNLPEIFLFASLGPNNVIFINKELVGRKLAKWVEMSD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .** . .. . . : *:* * : . : . : * :.. ... * : .. * * :* .: * ::. *.:: . : : : . : . . . : :. .. : : *. . : .:. .: :: : .*: ..:.: :* .:. . : : *. . :*... : . * :.. * . ... .:* * . : *** *: * . :: .:*: : * *.: . :* : . . . :*: .* *:*:* *:: ::. :* .: *.: :.. **: .::** ***:: .:* ** :* ::: . .*: .**. :* . : : * * :**. :*:* :...*:*:*: **:. :* *::*:* .** * **: :*::.:*. * :..*:*.*:* : *: :. *:::*:*** .* .:.*****:**:.:***.:* :*..: *:.. :* ** :.::* . .* ***:.*.. .** * *:: :* ::*::**:.** * **:**: ", "identical_positions": 125, "similar_positions": 226, "identity": "13.66%" }, { "cls_id": "homologset.agr.RGD:620827", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97808-1", "uniprot_id": "FXYD5_MOUSE", "id": "P97808-1", "name": "FXYD domain-containing ion transport regulator 5", "aln": "MSLSSRLCLLTIVALILPSRGQTPKKPTSIFTADQTSATTRDNVPDPDQTSPGVQTTPLI--WTRE--EATGSQTAAQTETQQLTKMATSNPVSDPGPHTSSKKGTP---AVSRIEPLSPSKNFMPPSYIEHPLDSNENNPFYYDDTTLRKRGLLVAAVLFITGIIILTSGKCRQLSQFCLNRHR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59647-1", "uniprot_id": "FXYD5_RAT", "id": "P59647-1", "name": "FXYD domain-containing ion transport regulator 5", "aln": "MSPPSQLCLLTIVALILPSEGQTPEKPRSSFTAHQSSVTT--HVPVPDQTSPGVQTTPPI--WTSEAGEATGSQTAAKTKTQQLTEMATANPVTDPGPLTSSEKGTP---ALSRIKSPSPPKGYMPPSYIENPLDPNENSPFYYDNTTLRKRGLLVAAVLFITGIIILTSGKCRQFSQLCLNRHR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96DB9-1", "uniprot_id": "FXYD5_HUMAN", "id": "Q96DB9-1", "name": "FXYD domain-containing ion transport regulator 5", "aln": "MSPSGRLCLLTIVGLILPTRGQTLKDTTSSSSADSTIMDIQVPTRAPDAVYTELQPTSPTPTWP------ADETPQPQTQTQQLEGTDGP-LVTDPETHKSTKAAHPTDDTTTLSERPSPSTDVQTDPQTLKPSGFHEDDPFFYDEHTLRKRGLLVAAVLFITGIIILTSGKCRQLSRLCRNRCR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ..:*******.****:.*** :.. * :*..: . ** . . :*.*. *. :.. . .:*:**** . *:** . .*:: . * : : : **... . . :* . :*:.**:**: ****************************:*::* ** *", "identical_positions": 74, "similar_positions": 52, "identity": "40.0%" }, { "cls_id": "homologset.agr.RGD:620828", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60662-1", "uniprot_id": "AKAP4_MOUSE", "id": "Q60662-1", "name": "A-kinase anchor protein 4", "aln": "MIAYCGTTTMSDDIDWLHSRRGVCKVDLYSPKGQQDQDRKVICFVDVSTLNVEDKDSKGAAGSRSEGELNLETLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPISVLNWLLNDLQKYALGFQHALSPSASSCKHKVGDLEGDYSKIPSENCYSVYADQVNFDYLNKGPQNLRLEMAASKNTNNNQSPSNPATKSPSNQRSVATPEGECSMDDLSFYVNRLSSLVIQMARKEIKDKLEGGSKCLHHSMYTS-GDKGKTSPRSAVSKIASEMAHEAVELTSSEMRGNGEDCRDG-RKTFLYSEMCNKNKCGEKQQMCPKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSCGKPIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGKQNAADIMEAMLKRLVSALLGEKKETKSQSLAYATLKAGTNDPKCKNQSLEFSAMKAEMKGKDKCKSKADPCCKSLTSAERVSEHILKESLTMWNNQKQGNQGKVTNKVCCTSKDEKREKISPSTDSLAKDLIVSALMLIQYHLTQQAKGKDPCEEECPGSSMGYMSQSAQYEKCGGGQSSKSLSMKHFETRGAPGPSTCMKENQ-LESQKMDMSNMVLSLIQKLLSESPFSCDELTESDNKRCCDPRSSKAAPMAKRP---EEQCQDNAELDFISGMKQMNRQFIDQLVESVMKLCLIMAKYSNNGAALAELEEQAALVGS----GSRCGRDAMMSQNYSETPGPEVIVNNQCSTTNLQKQLQAVLQWIAASQFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMKFAKERQLDEAVGNMARKQLLDWLLANL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35774-1", "uniprot_id": "AKAP4_RAT", "id": "O35774-1", "name": "A-kinase anchor protein 4", "aln": "MIAYCGTTKMSDDIDWLHSRRGVCKVDLYSPEGQQDQDRKVICFVDVSTLNVED-DSKGAAGPRSDGELNLENLEEKEIIVIKDTEKQDQPKTEGSVCLFKQAPSDPISVLNWLLNDLQKYALGFQHALSPSASSCKHKVGDLEGDYHKIPSENCYSVYADQVNLDYLNKGPQNLRLEMAASKNTNNNQSPSNPATKSPSNQRSVATPDGECSMDDLSYYVNRLSSLVIQMARKEIKDKLEGGNKCLHHSMYTS-GEKGKTSPRSAVSKIASEMAHEAVELTSSEMRGNGEEGRDG-RKTFLYSELSNKNKCGEKQQMCPKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSCGKPIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGKQNAADIMEAMLKRLVSALLGEKKETKSQSLAYATLKAGTHDPKCKNQSLEFSAMKAEMKGKDKGKTKGDPCCKSLTSAERVSEHILKESLTMWNNQKQGTQGRVPNKVCP-SKDEKREKISPSTDSLAKDLIVSALMLIQYHLTQQAKGKDPCEEECPGSSMGYMSQSAQYEKSGGGQSSKSLSMKHFESRGAPGPSTCAKENQ-LESQKMDMSNMVLSLIQKLLSESPFSCDELSESENKRCCDSRSKQAAPVAKRP---EDQSQDSTEMDFISGMKQMNRQFIDQLVESVMKLCLIMAKYSNNGAALAELEEQAALASN----GPRCGREAVMSQSYLETPGPEVIVNNQCSTSNLQKQLQAVLQWIAASQFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMKFAKERQLDEAVGNMARKQLLDWLLANL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JQC9-1", "uniprot_id": "AKAP4_HUMAN", "id": "Q5JQC9-1", "name": "A-kinase anchor protein 4", "aln": "MMAYSDTTMMSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHALSPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNKSKSGDKQ-MSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDP-CKSLTSAEKVGEHILKEGLTIWN-QKQGNSCKVATKACS-NKDEKGEKINASTDSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENK-CSEPRASKAASMSNRSDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAASANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDWLLANL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**..** ********:*:*********.*:********************** * *.**.. *:*:*** .**************:**.****************:*******.****************:*:******* **:* : .*************:*** : ********:*:********** *.:*.**.**:* :*:****:****:*************:****:**** .******: .* *:* : ***:..********:******::****.**: *:* :*:*****:.**.*.*:** *. ::**************************:********.******.********:****************************************: ****:**************:**:********:**:****::****:*******:****** :** * *.** ********:*.******.**:** ****.. :*..*.* .**** ***..************** *********:****.***:****:****:**:****.*****:*:**:*::*:: ******* **** *:********:** ******.*.**.*:: *.:** *.:.*:.:**.:::*. *:*.*: *:* ***** * ****:*****************:************ ... *.** :.. *.*.* :: * **********..***************************.********:*************.************* *****::*************", "identical_positions": 652, "similar_positions": 148, "identity": "75.9%" }, { "cls_id": "homologset.agr.RGD:620829", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3YVF0-1", "uniprot_id": "AKAP5_MOUSE", "id": "D3YVF0-1", "name": "A-kinase anchor protein 5", "aln": "METSVSEIQVETKDEKGPVAASPQKERQERKTATLCFKRRKKANKT-KPKAGSRTAEETKKHTPEAGGSGQRQP-AGAWASIKGLVTHRKRSEPAKKQKPPEAEVQP----EDGALPKKKAKSRLKFPCLRFSRGAKRSRHSKLTEDS-GYVRVQGEADDLEIKAQTQPDDQAIQAGSTQGLQEGVLVRDGKKSQESHISNSVTSGENVIAIELELENKSSAIQMGTPELEKETKVITEKPSVQTQRASLLESSAAGSPRSVTSAAPPSPATTHQHSLEEPSNGIRESAPSGKDD-RRKTAAEEKKSGETALGQAEEAA-VGQADKRALSQAGEATAGHPEEATVIQAESQAKEGKLSQAEETTVAQAKETVLSQAKEGELSQAKKATVGQAEEATIDHTEKVTVDQAEETTVGQAEEATVGQAGEAILSQAKEATVVGQAEEATVDRAEEATVGQAEEATVGHTEKVTVDQAEEATVGQAEEATVGQAEEATVDWAEKPTVGQAEEATVGQAEEATVGHTEKVTVDQAEEATVGQAEEATVGHTEKVTVDHAEEATVGQAEEATVGQAEKVTVDHAEEATVGQAEEATVGQAEKVTVDHAEEATVGQAEEATVGQAEKVTVDQAEEPTVDQAEEAISSHAPDLKENGIDTEKPRSEESKRMEPIAIIITDTEISEFDVKKSKNVPKQFLISMENEQVGVFANDSDFEGRTSEQYETLLIETASSLVKNAIELSVEQLVNEMVSEDNQINTLFQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24587-1", "uniprot_id": "AKAP5_RAT", "id": "P24587-1", "name": "A-kinase anchor protein 5", "aln": "METSVSEIQIETKDEKRPEAASPQKERQERKTATLCFKRRKKVNKK-KAKAGSKTAEETEKHAPEAGGSGQRQP-AGAWASIKRLVTHRKPSESAEKQKPSEAEMQP----EDGALPKKKTKSKLKIPCIRFSRGAKRSRPSKLTEDS-GYVRVQGEADDLEIKAQIQPDEQATQAKSTQGLQEDVIVRDGKEIQESHISNNVISGEHVIGIELELEKESSALRMRTPGSEKEAKVILVKQGVQVQEASVLENSAADSPQPVTSTAPLSPATTHQLGLEEPSDSIRESAPSGKDDGRRKTAAEEKKSGETALGQAEEASSVSQADKSVLSQAEEATVGHTEEATVIQAQSQAKEGKLSQAEEATVAQAKETVLSQAEEVKLS------------------------QIEEPAISQAKKATVGQAKEAYVS---------QAEEAIVGHTEKATMGQAEEATVGHIEKTTVGQAEEATVGQAEEATVGQAEEATVGQAEEATVGQAEEATVGQAGEATVSHIEKTTVGQAEEAIVGQAEEATVGQAEEATVGQAEEATVGQAEEATVDQAEEATVGQAEEATVGQAGEAAVGQAEEAIVAQAEEATVGQAGEATVGQAEKATVGQAEEPIVGQAEETVLRHASDLKVNGVDAEKPRSEESKRMEPIAIIITDTEISEFDVKKSKNVPKQFLISMENEQVGVFANDSDFEGRTSEQYETLLIETASSLVKNAIELSVEQLVNEMVSEDNQINTLFQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24588-1", "uniprot_id": "AKAP5_HUMAN", "id": "P24588-1", "name": "A-kinase anchor protein 5", "aln": "METTISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILE-EIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKP-------------------------------------------------------------KDTELSQE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDFKENGITEEKSKSEESKRMEPIAIIITDTEISEFDVTKSKNVPKQFLISAENEQVGVFANDNGFEDRTSEQYETLLIETASSLVKNAIQLSIEQLVNEMASDDNKINNLLQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::***::*.**** . .** ***:.*:: ********. * *.****.:*: :.* . ***.*.* :* *****:* ***:** **.:::*** *.*:** **. *.***:**:**:**::*.**.***. **: *** ::** **: *:*::* ::** :* ***.*.*.: :**.: **::**.. ***:**.:** *:: **:: * * * :.* * .** *.** **.* :. :.* * .* ** ..* :**.*:. ****.*** : .***.*. *:* *** .*:* **: **.:************************.************ ***********..**.**********************:**:*******.*:**:**.*:*", "identical_positions": 244, "similar_positions": 106, "identity": "32.36%" }, { "cls_id": "homologset.agr.RGD:62083", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17659-1", "uniprot_id": "KCNA6_RAT", "id": "P17659-1", "name": "Potassium voltage-gated channel subfamily A member 6", "aln": "MRSEKSLT-LAAPGEVRGPEGEQQDAG---------------------------------------EFQEAEGGGGCCS----------------SERLVINISGLRYETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFMEEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRADGRGGSNEGSGTRMSPASRGSHEEEDEDEDSYAFPGSIPSGGLGTGGTSSFSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKAAFFRNIMNIIDLVAIFPYFITLGTELVQRHEQQPVSGG----SGQNRQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDVDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQG--QYTHVTCG-----------------QPTPDLKATDNGLG-KPDFAEASRER------------------------------RSSYLPTPHRAYAEKRMLTEV--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61923-1", "uniprot_id": "KCNA6_MOUSE", "id": "Q61923-1", "name": "Potassium voltage-gated channel subfamily A member 6", "aln": "MRSEKSLT-LAAPGEVRGPEGEQQDAG---------------------------------------EFQEAEGGGGCCS----------------SERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFMEEIRFYQLGEEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRADGRGGSNEGSGTRLSPASR-SHEEEDEDEDSYAFPGSIPSGGLGTGGTSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKAAFFRNIMNIIDLVAIFPYFITLGTELVQRHEQQSVSGG----SGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDVDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQG--QYTHVTCG-----------------QPTPDLKATDNGLG-KPDFAEASRER------------------------------RPSYLPTPHRAYAEKRMLTEV--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17658-1", "uniprot_id": "KCNA6_HUMAN", "id": "P17658-1", "name": "Potassium voltage-gated channel subfamily A member 6", "aln": "MRSEKSLT-LAAPGEVRGPEGEQQDAG---------------------------------------DFPEAGGGGGCCS----------------SERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNN-GGVSRVSPVSRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQPASGG----GGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQG--QYTHVTCG-----------------QPAPDLRATDNGLG-KPDFPEANRER------------------------------RPSYLPTPHRAYAEKRMLTEV--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08510-1", "uniprot_id": "KCNAS_DROME", "id": "P08510-1", "name": "Potassium voltage-gated channel protein Shaker", "aln": "MAAVAGLYGLGEDRQHRKKQQQQQQHQKEQLEQKEEQKKIAERKLQLREQQLQRNSLDGYGSLPKLSSQDEEGGAGHGFGGGPQHFEPIPHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKE---EERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHY----------KVFNTTTNGTKIEEDEVPD----------------------------ITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYLPGTLGQHMKKSSLSESSSDMMDLDDGVESTPGLTETHPGRSAVAPFLGAQQQQQQPVASSLSMSIDKQLQHPLQQLTQTQLYQQQQQQQQQQQNGFKQQQQQTQQQLQQQQSHTINASAAAATSGSGSSGLTMRHNNALAVSIETDV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : .* *. : * : :**: . : **.* .**:***:****:*******. *********.**:*:************.**************************:* ***:**:**::*: ****** : * :*:***.: **:*********** .** :**:**:***:***********:*: . ....:. :: **:: * :******:*****:****** *** ***.* * *::**:**::**:******.* :.:..: . . .:. :*********************************:**:*****************:***********.. :*:* ********************* *: * ***********************************:*** ::.***. :.:.*: *:*: .*.:.*: * :. * : * ::: : ", "identical_positions": 308, "similar_positions": 104, "identity": "44.25%" }, { "cls_id": "homologset.agr.RGD:620830", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59648-1", "uniprot_id": "FXYD7_MOUSE", "id": "P59648-1", "name": "FXYD domain-containing ion transport regulator 7", "aln": "MATPTQSPTNVPEETDPFFYDYATVQTVGMTLATIMFVLGIIIILSKKVKCRKADSRSESPTCKSCKSELPSSAPGGGGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59649-1", "uniprot_id": "FXYD7_RAT", "id": "P59649-1", "name": "FXYD domain-containing ion transport regulator 7", "aln": "MATPTQSPTNVPEETDPFFYDYATVQTVGMTLATIMFVLGIIIIISKKVKCRKADSRSESPTCKSCKSELPSSAPGGGGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58549-1", "uniprot_id": "FXYD7_HUMAN", "id": "P58549-1", "name": "FXYD domain-containing ion transport regulator 7", "aln": "MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKKVKCRKADSRSESPTCKSCKSELPSSAPGGGGV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:**:.***.***:*** ************:*:***:*::***********************************", "identical_positions": 69, "similar_positions": 10, "identity": "86.25%" }, { "cls_id": "homologset.agr.RGD:620831", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54756-1", "uniprot_id": "EPHA5_HUMAN", "id": "P54756-1", "name": "Ephrin type-A receptor 5", "aln": "--MRGSGPRGAGRRRPPS--GGGDTPITPASLAGCYSAP---------------------RRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKN-GWEEIGEVDENYAPIHT------YQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRN--IKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNA-ISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQY--------------------------------VSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSY--TIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPV-FAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGR-ASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPG--KRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54757-1", "uniprot_id": "EPHA5_RAT", "id": "P54757-1", "name": "Ephrin type-A receptor 5", "aln": "--MRGSGPRGAGRRRTQGRGGGGDTPRVPASLAGCYSAP---------------------LKGPLWTCLLLCAALRTLLASPSNEVNLLDSRTVLGDLGWIAFPKN-GWEEIGEVDENYAPIHT------YQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDENGRN--IKDNQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDDPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQVCRPGFFKASPHSQTCSKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNA-ISNVNETSVFLEWIPPADTGGGKDVSYYILCKKCNSHAGVCEECGGHVRYLPQQIGLKNTSVMMADPLAHTNYTFEIEAVNGVSDLSPGTRQY--------------------------------VSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSY--TIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPV-FGASNDQSQIPIIGVSVTVGVILLAVMIGFLLSGSCCECGCGR-ASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPTQAVHEFGKEIEASCITIERVIGAGEFGEVCSGRLKLPG--KRELPVATKTLKVGYTEKQRRDFLSEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDDIVNMLDKLIRNPSSLKTLVNASSRVSTLLAEHGSLGSGAYRSVGEWLEATKMGRYTEIFMENGYSSMDAVAQVTLE----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60629-1", "uniprot_id": "EPHA5_MOUSE", "id": "Q60629-1", "name": "Ephrin type-A receptor 5", "aln": "--MRGSGPRGAGHRRTQGRGGGDDTPRVPASLAGCYSAP---------------------LKGPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKN-GWEEIGEVDENYAPIHT------YQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDENGRS--IKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAIFPDTITGADSSQLLEVSGSCVNHSVTDDPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSY--TIIKSKETSITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVSVAASNDQSQIPIIAVSVTVGVILLAVMIGFLLSGSCCDCGCGR-ASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPG--KRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSSSDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVNMLDKLIRNPSSLKTLVNASSRVSTLLAEHGSLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMSSLQEMKVQMVNGMVPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAH-ADQVVLLDT-TREATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHNVNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFDAATREPPPWQTDSYRLIARIAAGEGRFNQNS---DVDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCVDNAEPYETPTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFK-SPEVTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISWSAPAKNESFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIEN-ASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILD-GQRGQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *. *.. : .... .: * .. ** . * * **: ::: ** :::* ***: * . * * :* . : * *:*.:: : . * **.* :* **** :.:*.. .*.*::**::**:***. :**. :*****.: ::* * . . : :.* * ***.*. : : :.:****:.:. :.***.*:**:* ****::::*:*** .**:*..::* * :* ** : : : : .*:**::: . :.*. *..:*:* : * * ****** .* ** *.* *:: *:::. .*.*::* :.: : **:::* * : : : :::***. ** : * **:*.:* *:* :*. : :* .. .*. ** .*. ::..**::*.:.* : .. . .* :. * .. . * :*:*:: : . *:*:********.**::**.:**:*. **** :**.****:** ****:* ::: ** **** * :** * *** ************:*:*:****:*:****:*************: ***:* .:**: *****::**.*****.**********:*:*::*:**::****** :*: .. **********:***************:*******:*:***:********: :******::*:*****:***** ************:*. **.* .**. **:* *:*.** * :. .. : : . *.. : *.. *** **.** . * * . . : ::::* : ", "identical_positions": 362, "similar_positions": 254, "identity": "32.55%" }, { "cls_id": "homologset.agr.RGD:620832", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DBR0-1", "uniprot_id": "AKAP8_MOUSE", "id": "Q9DBR0-1", "name": "A-kinase anchor protein 8", "aln": "MEQGYGGYGAWSAGPANTQGTYGSGMTSWQGYENYNYYNAQNTSVPAGTPYSYGPASWEATKTNDGGLAAGSPAMHVASFAPEPCTDNSDSLIAKINQRLDMLSKEGGRGGISSGGEGVQDRDSSFRFQPYESYDARPCIPEHNPYRPGYGYDYDFDLGTDRNGSFGGTFNDCRDPAPERGSLDGFLRGRGQGRFQDRSNSSTFIRSDPFMPPSAS-EPLSTTWNELNYMGGRGLGGPSTSRPPPSLFSQSMAPDYSMMGMQGVGGFGGTMPYGCGRSQTRIR--DWPRRRGFERFGPDNMGRKRKQFPLYEEPDAKLARADSDGDLSENDDGAGDLRSGDEEFRGEDDLCDSRKQRGEKEDEDEDVKKRREKQRRRDRMRDRAADRIQFACSVCKFRSFEDEEIQKHLQSKFHKETLRFISTKLPDKTVEFLQEYIINRNKKIEKRRQELLEKESPKPKPDPFKGIGQEHFFKKIEAAHCLACDMLIPAQHQLLQRHLHSVDHNHNRRLAAEQFKKTSLHVAKSVLNNKHIVKMLEKYLKGEDPFVNETADLETEGDENVG-EEKEETPEEVAAEVLAEVITAAVKAVEGEGEPAAAHSDVLTEVEGPVDTAEASSDPHTEKLLEEQT-CEAASETRSIEDKTRGEAAEARNEAAMPTADAGSTLP-VIAIPGIMEDELEQTGAEAKD-IPTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63014-1", "uniprot_id": "AKAP8_RAT", "id": "Q63014-1", "name": "A-kinase anchor protein 8", "aln": "MEQSYGGYGAWSAGPANTQGTYGSGVASWQGYENYSYYNAQNTSVPTGTPYSYGPASWEATKASDGGLAAGSSAMHVASFAPEPCTDNSDSLIAKINQRLDMLSKEGGRGGISSGGEGMQDRDSSFRFQPYESYDSRPCMPEHTPYRPSYSYDYDFDLGTDRNGSFGGTFNDCRDPTPERGALDGFLRGRGQGRFQDRSNSSTFIRSDPFMPPSASSEPLSTTWSELNYMGGRGLGGPSTNRPPPSLFSQSMAPDYSMMGMQGVGGFGGTMPYGCGRSQTRIR--DWPRRRGFERFGPDNMGRKRKPFPLYEEPDAKLARADSEGDLSENDDGAGDLRSGDEEFRGEDDLCDSRKQRGEKEDEDEDVKKRREKQRRRDRMRDRAADRIQFACSVCKFRSFEDEEIQKHLQSKFHKETLRFISTKLPDKTVEFLQEYIINRNKKIEKRRQELLEKESPKPKPDPFKGIGQEHFFKRIEAAHCLACDMLIPAQHQLLQRHLHSVDHNHNRRLAAEQFKKTSLHVAKSVLNNKHIVKMLEKYLKGEDPFVNETADLETEGDENLG-EEKE-TPEEVAAEVLAEVITAAVKAVEGDGEPAAEHSDVLAEVEGPVDTAEAGSDSHTGKLLEEQT-CETASETRNMEDMARGEAAEARNEAAVPAAAAGSPVP-VIAIPGILEDELEQTDAEAKD-TPTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43823-1", "uniprot_id": "AKAP8_HUMAN", "id": "O43823-1", "name": "A-kinase anchor protein 8", "aln": "MDQGYGGYGAWSAGPANTQGAYGTGVASWQGYENYNYYGAQNTSVTTGATYSYGPASWEAAKANDGGLAAGAPAMHMASYGPEPCTDNSDSLIAKINQRLDMMSKEGGRGGSGGGGEGIQDRESSFRFQPFESYDSRPCLPEHNPYRPSYSYDYEFDLGSDRNGSFGGQYSECRDPARERGSLDGFMRGRGQGRFQDRSNPGTFMRSDPFVPPAASSEPLSTPWNELNYVGGRGLGGPSPSRPPPSLFSQSMAPDYGVMGMQGAGGYDSTMPYGCGRSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGDFRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFHKETLRFISTKLPDKTVEFLQEYIVNRNKKIEKRRQELMEKETAKPKPDPFKGIGQEHFFKKIEAAHCLACDMLIPAQPQLLQRHLHSVDHNHNRRLAAEQFKKTSLHVAKSVLNNRHIVKMLEKYLKGEDPFTSETVDPEMEGDDNLGGEDKKETPEEVAADVLAEVITAAVRAVDGEGAPAPESSGEPAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKG--VPKARSEAAEAGNGAETMAAEAESAQTRVAPAPAAADAEVEQTDAESKDAVPTE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.****************:**:*::********.**.******.:*:.**********:*:.*******:.***:**:.*********************:******** ..****:***:*******:****:***:***.****.*.***:****:******** :.:****: ***:****:*************..**:*****:**:** *****.*.****:*********..***************.:*****.**:..**********.*:* * *:****:*****. ***** * ******:****.**:**:*****.***:*******:***:**** :************************ ********************:************************************:*************:***:.*****************:**************** *************************************:****************..**.* * ***:*:* *:*: *******:**********:**:*:* **. *. :* ***.*****.**.:: :*****. * :* *. :*.***** * * :* * *. . * . *. : *:***.**:** ***", "identical_positions": 535, "similar_positions": 110, "identity": "77.09%" }, { "cls_id": "homologset.agr.RGD:620833", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K548-1", "uniprot_id": "A0A0G2K548_RAT", "id": "A0A0G2K548-1", "name": "", "aln": "MEDEERQRKLAAGKAKLARFRQRKAQCDGDIP-KKQKKKR-TPSSKQDSSLHTDQ-----QSAEICSESSQRADSAGSPDS------SSAEKAKHGQVFAADPESEISTTADECSSEINGCNSVTKPGNPTDTLREEDFSIDDSYSEQGAQSSQTCLQMGENELAEKQHEVEELTQELEEMRASFGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARKEKDDTTIEFLELTEQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTLQQQLQ-------DYQKKEEDVQAQISFLQEKIRMLEMEKDRKVESLNTKEIEEKQAIIEELNTRVIEEERKTAELENKVTTADELLGQLQGQVTEKDQEIKSLKLELVNSQQNERKCSEEIKELMRTVEELQKRNLKDSQLGTGTVRRVEQETQRKLSLLQAELDEMYGKQIVQMKQELMKQHMSQIEELKSQHKRDLENTLKSDASTTVSKEQVNLMSAAISELNVRLQDTHAQKEKLKGELGAALGEKSALQSQFEDLLEEVRFLREQVQKARQTIAEQENRLSDARKSLSTVEDLKAEIVAASESRKELEVKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEVEHRINVEKLKDNLGIHYKQQIDGLQNEMNRKMETMQCETDNLITRQNQLILENSKLRDLQEHLVNSKSEEMNLQINELQKEIEILRREEKEKGSLEQEVQGLQLKTEQLERQLKEKGDDLQEKCAQLDAENSVLKDEKKALEDMLKMYTPLDQE------DPSTRKSEDPRWQKEVGMLRKENEDLQQQCLHLSEEIEKQKNTFAFAEKNFEVNYQELQREYTCLLKIRDDLEDTLAKQALQYESKLSALEEELHSQRGSPTTPPKGENSGFAANRTFPLEPLEVGEVVEKDTTELMEKLEVTRREKLELSEKVSGLSEQLKQTHGTIDSLSEEVRALKQEKEQLLLRCGELELLTNANGTENASVCPVQRSPYQAGPVMGTVRDSQGPISKVSEDLAEESKPMTEDKIPFK------ESGREPLLL---PTRTKKPSRVTVEPCESEKLQQELYALKAEQDDLRLQMEAQRLCLFVVYSTHADQVRAYMEKEREEALCSLKDELVSAQQKKIDELHKIHQCQLQHVKVQETGNE--PLQVLIERLQKAVSEKCFHISKTLNNVFDECYTP-LKCEMNIEEKENSGVYTSQNQSPELREYRYEVQDFQENMQILLGKVTEECSKLLVLQTRLNKINEQQVDGVTFEFAEENVAEVEAGLLSGRSQSG-LQGADVSHESKVS---------EYERQVQELQSLVAAGQLQLKETEANYRAEIQCLQERLQAVSEATVQPSLSMDSVVFKGSGAQKPVYCGSCLREQVDGTAEFSDGFEVRQETNMVKLMEKQYQERLEEEIAKVIVSMSIAFAQQTELSRLSEEKENVIQSEQAHALCSQNEHHLNDITS-QCQVGLQTVEATGKNLKEEFKPLSKELGEYRKAVPLSNHDDLDDVLKSEEHGLTISEEIFSKDETFLVRNSSPDEVLVSNMDTSRQLILN-EQLEDMRQELVRQYEEHQQATELLRQAHMQQMERQREDQEQLQEEIKRLNQQLTQRSSIDTEHVVSERERVLLEELEALKRLSLAGRKELCCELQHSSTQTQDGNDNQ-EVEEQTLKDKTLERKPEDIPLDINLSNERYALKKANNRLLKILLDVVKTTSAAEETIGRHVLGILDRSSKSQPATSLLWRSETEASATVCVQEECARAMDESVPSYPGSAIATHDS-VWSKVTEEGAELSQRLVRSGFAGPVIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAVELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQELLCTNNRLQELESDQRRMEEERELLSRQREAMRADAGPVEQRPIAAAAGAAPGAEFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAELIDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRLLPVSEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDVQERNEEIEKLECRVRELEQALLATADPFPKVEEQKRPGAVEVDPELSLEVQLQAERDATDRKQKEITNLEEQLEQFREELENKNEEVQELLMQLEIQKKESTTRLQELQQENRLFKEEIEKLGFTMKESDSLSTQDQPMLFGKFAQLIQEKEIEIDRLNEQFIKLQQQLKLTTDNKVIEEQKDQIRDLETQIECLMSEQELMKKQRAEEAEQLNGVIEKLQQELVSTEQKR-EGARALPEDEESFKHQLDRVTVEKLGLEKQVETTNQELTDLKNVLKEINFKMDHMTQALCNLN------KELPNVPKESVHVTVHELGCDKLQPEGASAQDASQPLESQTSLMCLQESTKASQI-LEIKSLPLQGSGSTKDFELAQCHKQIDTIQEQDQSEIGMLQKKITNLQKILEK-FSAALVSWVQMEAAQDRVQLYQEKQTQTVSSAPERTDTQNVNCLAENNLESHVPTLAVRPAELESRVAEVLSDIMSEK-HMETVGKNASETEKEVVALQKLLEEAKKRLKE-EREQSPRDRERTAQLTHAGGGSGFSGGLETFEAE-----SATSELASYKERAEKLEEDLLVKESYITSLQKDLGQVKDQLTEAKEKLSHYLEKENGTGEQESRRVPIPESPSVEGGG-GSGTMERTGKVSSS-NQTPQILVRHAGVQIDLQSERSQEELRDTINQFTEKMERIQELHAAEILDMESRHILETESLKKEHSVAIQLLTKECETLKDMTQYLRCKKGSSISDLADSVAYQSREVYSSDSESDWGQ------SQGFDTATEGR-EEGETS-DLFPKKIKGLVKAVHSEGMQVLSLSNPLCDDGEDRSVQQLSESWLKERQTYLNTISSLKDLISKMQVQRETEVYDSCQSHDSFSDWRGELLLACQRVFIKERSVLLATFQTELTSLSTRDADGVLNSLEQRIQEQGIEYQTAMDCLQKADRRSLLTEIEDLRAQINGRKMTLEREQEIEKPSQELLDCNLQQKQSHVLEMQLELGSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEIKEKTDEIHFLSDTLAREQKKSLELQWALEKEKAKSGHHEEWEKEELEDLKFSLEDQKRKNTQLNLLLEQQKQLLNESQQKMESQKMLHDAQLSEEQGRNLGLQALLESEQVRVQEMKSTLDKERELYAQLQSRDDGGQPLPVLPSEDLLKELQKQLEEKHTRIVELLSETEKYKLDSLQTRQQMEKDREVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGKRLQGIMQEFQKQELEPEEKRGSRGLVYQNLNEPASWTFTDDRTRNWVLQQKMG-ETKDTNFTKLIEING-ELDHNHDLEVIRQTLQHVASKLQHVAQKACNRLQFETASDDAFIWIQENIDGIILQLQKLTGQPGDEHSLAPPSSSCGSLTESLMRQNTELTRLINQLTEEKNTLRSIVVKLEELNRCHWHTGAGRDCCSRFSFIDPADIEAIIASEKEVWNREKLSLQKALKRAEAKVYKLKAELRNDALLRSLSPDSEHAALQKIYNKYLRASSFRKALIYQKKYLLLLLGGFQECEDATLGVLARMGGHPALKDPKTITSHPKGFTRFRSAVRVSIAISRMKFLVRRWQQVTSTSSININRDGFGLSPGIEKTDPFYHSSGGLELYGEPRHTTYRSRFDLDYPRSPLPLQNRYPGAP-DLNSTSMASSQLHQYNPDKSLTDYVTRLEALKRRLGAIQSGSTTQFHFGMRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q70FJ1-1", "uniprot_id": "AKAP9_MOUSE", "id": "Q70FJ1-1", "name": "A-kinase anchor protein 9", "aln": "MEDEERQRKLAAGKAKLARFRQRKAQYDGDIP-KKQKKKR-TSSSKHDSSLHTDQ-----QSGELCSESSQRVDLAGNPDC------SGPER-KHGQVFSAEPESEISTTADECSSEINGCNSVMKPRKPTDPLREEEFSLDDSSSEQGAQSSQTCLQMVEKELAEKQHDIEELTQELEEMRASFGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQ-------DYQKKEEDLQAQISFLQEKLRAFEMEKDRKIENLNAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQKRNLKDSWLETSAVRRVEQETQRKLSHLQAELDEMYGKQIVQMKQELINQHMSQIEELKSQHKREMENTLKSDTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVEDLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQPLFSHEEELSKLKEDLEVEHRINIEKLKDNLGIHYKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLEDKLKMYSPSEQEERSIAVDPSTSKLADSRWQKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAEKNFEVNYQELQREYTCLLKIRDDLEATQTKQALEYESKLRALEEELLSKRGNPX-APKGKSSG-----IFPSETLEIGEVVEKDTTELMEKLEVTKREKLELSEKVSGLSEQLKQTHCTINSLSAEXRALKQEKEQLLLRCGELELLANPSGTENAAVCPVQMSSYQAGLVMGKVGDSGGSISKISKDLAEESKPMIEDKIPFK------ESGREQLLL---PTRAQEPSHATVEPCESEKLQQELHALKAEQDDLRLQMEAQRICLFVVYSTHADQVRAHMEKEREEALCSLKDELISAQQKKIDELHKMHQCQLQNVKIQETGDE--PLQVLIERLQKAVSEKCFHISKTLNNVFDECYTP-LKCEMNIEEKENSGVYTSQNQSPELQEYRYEVQDFQESMQVLLGKVTEECRKLSGLQTRLGKIHEQQTDGVALEFAEQNAAEEEAGLLSGCSQSA-LQSTDVSLESKVSSLPASEKNRECERQVQELQSPVAAGQLQLTETEASHRAEIECLQQRLEAASEAPVQPSLSIDSVVFKGSGAQKPVYCGSCLREYVDGTAKFSDRFEVRQETNMVNLMEKQYQERLEEEIAKVIVSMSIAFAQQTELSRLSEGKENTIQSEQAHTLCSQNKHQLNDITS-QSQVGLQTFEATDKBFKEEFKPLSKELGEYRKAVPLSSHDDLDDILKSEEHGLAISEEIFSKDETFIVRKSMHDEVLVSSMDTSRQLILN-EQLEDMRQELVRQYEEHQQATEMLRQAHMQQMERQREDQEQLQEEIKRLNEQLTQKSSIDTEHVVSERERVLLEELEALKQLPLAGRKELCCELRHSSTQTQDGHDDQ-EVEEQTLKDKTLERSPEDALLDRNLSNERYALKKANNRLLKILLEVVKTTSAAEETIGRHVLGILDRSSKGQTASSLLWRSEADASATTCAPEDCARAMDESIPSYPGTAIATHDS-IWSKVTEEGAELSQRLVRSGFAGPVIDPENEELMLNISSRLQAAVEKLLEAISETNTQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQ-------------QFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKAAPRIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSGAVAADPELSLEVQLQAERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFKDEIEKLGFAMKESDSVSTRDQPMLFGKFAQLIQEKEIEIDRLNEQFIKLQQQLKLTTDNKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQR-EGARTLPEDEESFKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKECASNEELPSLPKESVHMTVHELGSDNLQPEDAPAQDVTKPLEKQTSLTRLQESPEASRT-QEIESLAS--SVGAKDVELTQCREQTETIQEQAQSETDRLQKKLTDLQRSLEK-FAAALVSQVQMEAAQEYVPFHQEK--QPVSSAPGSTDIQNANGLTGASTESLIPTVTLRLAEVESRVAEVHSGTMSEK-LVGIVGGNASETEKRVIELQKLLEEAEERPEE-GGEQSSRDGE--------------------------------------------------VRESYMTSLQKDLGQVKDPLTEAKEKLSYSLEKEKRTGEQESREAPIPEPPSVEVGG-CSGLTERTDKVSSSGNQTLQILLRDAAIQTDLQSESSQEEVRDTINQLTKKMEHIQELHAAEILDMESRHILETESLKKEHYVAIQLLTKECETLKEMTQCLRCKEGSSIPELADSVAYQSREVYSSDSESDWGQ------SQGFDTAIEGR-EEGETSADLFPKKIKGLVKAVHSEGMQVLSLSSPLCDDGEDRSIQQLSESWLKERQAYLNTISSLKDLISKMQVRRETEVYDRCH----LSDWRGELLLACQRVFIKERSVLLATFQTELTSLSTRDVDGLLNSLEQRIQEQGIEYHTAMDCLQKADRRSLLAEIEDLRAQINGGKMTLEREQGTEKSSQELLDCSMQQKQS--LEMQLELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEVKEKTDEIHFLSDTLAREQKNSLELQWALEKEKARSGHHEEREKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQKMLHDAQLSEEQGRNLGLQALLESEQVRIQEMKSTLDKERELYAQLQSREDGGQPPPALPSEDLLKELQKQLEEKHSRIVELLSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGKRLQGLMQEFQKQELEPEEKPGSRGLVDQNLNEPATWNFTDDRTRNWVLQQKMG-EAKDRNFTKLIEINGGELDHNHDLEMIRQTLQHVASKLQHVAQKACSRLQFETAGDDAFIWIQENIDGIILQLQKLTGQPGDEHSLGPPSSSCGSLTESLMRQNTELTRLINQLTEEKNTLRSIVIKLEELNRCYWHTGASRDCCSRFSFIDPADIEAIIASEKEVWNREKLSLQKALKRAEAKVYKLKAELRNDALLRNLGPDTDHAALQKIYNKYLRASSFRKALIYQKKYLLLLLGGFQECEDVTLGVLARMGGHLALKDSKTITNHPKAFSRFRSAVRVSIAISRMKFLVRRWQQVTSTSSININRDGFGLSPGIEKTDPFYHSPGGLELYGEPRHTMYRSRFDLDYPRSLLPLQNRYPGTPGDLNSISMASSQLHQYNPDKSLTDYVTRLEALRRRLGAIQSGSTTQFHFGMRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99996-2", "uniprot_id": "AKAP9_HUMAN", "id": "Q99996-2", "name": "A-kinase anchor protein 9", "aln": "MEDEERQKKLEAGKAKLAQFRQRKAQSDGQSPSKKQKKKRKTSSSKHDVSAHHDLNIDQSQCNEMYINSSQRVESTVIPESTIMRTLHSGEITSHEQGFSVELESEISTTADDCSSEVNGCSFVMRTGKPTNLLREEEFGVDDSYSEQGAQDSPTHLEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPT-TVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLPSVTKESSLRATQPSENDKLQKELNVLKSEQNDLRLQMEAQRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIFAQEEKIKELQKIHQLELQTMKTQETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVLGEYYTPALKCEVNAEDKENSGDYISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKT-KLEEQVQELESLISSLQQQLKETEQNYEAEIHCLQKRLQAVSESTVPPSLPVDSVVITESDAQRTMYPGSCVKKNIDGTIEFSGEFGVKEETNIVKLLEKQYQEQLEEEVAKVIVSMSIAFAQQTELSRISGGKENTASSKQAHAVCQQEQHYFNEMKLSQDQIGFQTFETVDVKFKEEFKPLSKELGEHGKEILLS-NSDPHDIPESKDCVLTISEEMFSKDKTFIVRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQLSLAGREKLCCELRNSSTQTQNGNENQGEVEEQTFKEKELDRKPEDVPPEI-LSNERYALQKANNRLLKILLEVVKTTAAVEETIGRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSGSDMPRNDINMWSKVTEEGTELSQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQ-------------QLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDN--QTISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLS-ILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSS-NQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRSKEGSSIPELAHSDAYQTREICSSDSGSDWGQGIYLTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYINTISSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNAELTGHISQLTEEKNDLRNMVMKLEEQIRWYRQTGAGRDNSSRFSLNGGANIEAIIASEKEVWNREKLTLQKSLKRAEAEVYKLKAELRNDSLLQTLSPDSEHVTLKRIYGKYLRAESFRKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSIAISRMKFLVRRWHRVTGSVSININRDGFGLNQGAEKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYIRSPLPFQNRYPGTPADFNPGSLACSQLQNYDPDRALTDYITRLEALQRRLGTIQSGSTTQFHAGMRR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:** *******:******* **: * ******* *.***:* * * * *. *: :****.: : *:. . * .* * *:.: *********:****:***. * :. :**: ****:*.:*** ******.* * *:* *.*** ***::***.:******.::*****:***************************:***:* *****************:***.***:*** * **:******:**:* ****: *****:**. ********:: ***:*:*:*. * :**:**:::*:****:::***:** **::*:****:*** *: *:.:::***:.:**** **:*:**:.*****:** ********* *** : *. *:*:********. *:********:*********:.***:*:**:*::** ::**:*:* :. ::.::*::**..**.***::**:*::***:** *** * **.*** * :**:**: * ***:*:*********.:*.:*:**************:*********:*****:*********************************** ****************:*****:**********************.:*:*:** *.*****:******* ***:***: *********.*************::******:****** ****** **:*:*** :***** ***:***.:**:**:.*** **:::* .** *. . * *. *:**: :* :*.***:***: *.******:***:**************.**:****::**** : ** *:*:*** **:*** :* .* . * :.* * *.**:******************:*******:::*.*******.* *. *. * ::*******: *** ***:: * . :**. * .* *. * * . .: *.:**:.:.:.**** * ***:.*: ** :* *:* *: :::.* :.:*.*.:***:** .**:**:**********:** :*****.**** :**:*:::******:**: **::**.**:*:** :** :* ****:* **::** :*******:* :: :** .*:.* *** ****:* *:***** * *:*:.***::**********.*: **.***** ** *****.** **.**: :**.*:* .: *: :** ** *:. **. :**:* : *.*****:* ::: * **.*** .:.***.***:**:*.**:.* ***.:****:. *.**:.:* ***::: :*** :**. * *::***:*:*:******:****:*******************:* ***. .*:***::*.*::* :*::. * *:*:**.*:.. :*************: * : ** :.* .*: :*:: *:****:****:**:**:* **: **.**:****:** **************:*******:******:********************.**:*:****.*::****************:*.****::*****::******:*:::* ******:*:* *:*.*** : ********:***********:*****:*.*****************.*.::**:****::**.. *. *: :*. ***:***.*: :. :* :********:*************. ******************************.:***************************:* *******:********** **.***.*****:*****************::****:** .*******::*::::***:**.**:***:*:****** ::**********************.****************************:** *****.************************************:***..**: *:****:******:********:**************:*********** **********.:*:.* ***::*: *** ..*************** ***:*********************:***:* ******:**********:***:***:::****:::****::**:** :*******:*****:***:****. *******:*********::: *:******* ***::* *::* ** ***. *:******:.. *: .*::*.*: :*:***** * .*** **:****:*: :* ::***** ****:::** * .*: ::: .:*::**::::..*. *: : * . ::*. :.**.** : ::*. :.* * . * : .:**.**:** :* . :*** * * ****:.:**: :*: .:***** :*:**.*: . : *:: *.:** * *: ** * * . * :.::::* :*:**:*.*: :. : ** : . *. *.**.:: ****** ::: .* ::*.:* * *:*: :*******.**:* *:******* ****. * ***:.. : *. .:: . :. : * *:*** *** ***::.*.:* :**** *.**: : *.*:*:*:*::**************** ***:**:** **:***.:** *** : * **.*:****.:**.* ***:**: **** ***** ***** * *** **.*:: * ********::***.********:.. .****:*:**:**.**:**::*:**********:***::**:**** .: :********** *:**::*******:*:****:*.* *. *:**.*********:**::**:***********:**: *:**:** *:**:*** **.*****: .:***** ****:**.*::***:**********************:**** ********:******** *:*:****:*:*.**** ***:* ***********: *: ** :************.**::* *******************:***:**:************ **.*****:**::**.****:****:***** :. **. * ******************:******.********************:**:***********:*****:*******:*****:*************:****:********** *** ** :: ******::*.:*.***********: *:*: *::****:** . **:**:***.** ****** :.***..*******.*: ***:***** *********** *:* ** .**:******* *:***:*** *.******* **.:*:**** * : :***.** .****: . *:*****************:***:******:***********:**:.*.**::*.:*::**.*****.*************************.**.:******: *:.* :.**.:**.*:**********************::**.: ***********. * ****.****.************ **** **** ** **:******:* *:*. *:*.***::*:**::****:******:****:********** ****", "identical_positions": 2552, "similar_positions": 829, "identity": "64.97%" }, { "cls_id": "homologset.agr.RGD:620834", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PD4-1", "uniprot_id": "ARC1A_RAT", "id": "Q99PD4-1", "name": "Actin-related protein 2/3 complex subunit 1A", "aln": "---------MSLHQF--LLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWTKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQ-KDGIWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVD--EKPASTPWGSKMPFGQLMSEFGGSGT--GGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLRTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDVPKQSIQR---------------------NMSAMERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKT--LESSIQGLRIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0Q6-1", "uniprot_id": "ARC1A_MOUSE", "id": "Q9R0Q6-1", "name": "Actin-related protein 2/3 complex subunit 1A", "aln": "---------MSLHQF--LLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWTKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQ-KDGIWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVD--EKPASTPWGSKMPFGQLMSEFGGSGT--GGWVHGVSFSASGNRLAWVSHDSTVSVADASKSVQVSTLRTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDVPKQSIQR---------------------NMSAMERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKT--LESSIQGLRIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92747-1", "uniprot_id": "ARC1A_HUMAN", "id": "Q92747-1", "name": "Actin-related protein 2/3 complex subunit 1A", "aln": "---------MSLHQF--LLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWVKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQ-KDGVWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVD--EKPASTPWGSKMPFGQLMSEFGGSGT--GGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLKTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDIPKQSIQR---------------------NMSAMERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKT--LESSIQGLRIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O97182-1", "uniprot_id": "O97182_DROME", "id": "O97182-1", "name": "Actin-related protein 2/3 complex subunit", "aln": "--------MAETYTFGTSLASITCHAWNKDRTQIALSPNNHEIHIYSREGSDWKLADVLNQHDLRVMGIDWAKNTNRIVSCAADRNAYVWTQGDDGKWKPALVLLRINRAATCVKWSPAENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVTSLDWHPNNVLLLAGSTDYKVRVFSAFIKDIE--EPPTPTPWGNRKPLGQLMAEFRNSQTSGGGWINSVSFSSDGNKVCWVGHDSCVSIADATNGNTVIRCRTGYLPFLSCEWVSPTSVVVAGYSCVPLLYSLTADGKLVLSGKLDKSQKKESS---------------------GITAMRIFQSMDRNMRTENTDTVVDSIHQNAITSVRLYAGDKASATKVSTSGVDGQLVIWNVEQGGINGGMRNLQI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38328-1", "uniprot_id": "ARPC1_YEAST", "id": "P38328-1", "name": "Actin-related protein 2/3 complex subunit 1", "aln": "MSFSNSKDKSVVAVYKLVKAPIYSHCFSQDKSILAVTCETDCLVYRVSNNTPPVLFATLKDHDKTITAVDISIHG-RIVTCSQDRNAYVWEPLSDGTYKPTLVLLRINRAATSVTWAPNGYKFAVGSSARIIAVCYYEHENNWWVSKHIKKPIKSTINCLSWHANGVLLAAGGTDGFMRVFSGFIKGLDSKESVAGSPWGQKFPFGCLIREWY-----QGSYIHDVEWRSQMERIAYVAHDGTLNVVDYQSPVQSVNAPEG-LPYRSLVWINDHEIVCGGYSCHPVLFSEASEG-WKFAKNLDKSDNNKSSALTASGNTDELSGNNDESSTFGISALRKFKELDLKGKVS--TDVQESAHENAIVELRPFAESNGQITQVSSCGLDGKIVIYTI---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* .*.:.:*:: :*:: :.. : :.: *::*: : .:* : : ***:*. ******* .** :**:**:******** *.*:* ******.**:*:***:* **:***********:**: .*.**.*.*** **. * ****.:** :: * : :***.: *:* *: *: *.:::.*.: :. .::.:*.**. :.:.* . ** * ::. .:* .*:.* *:*:. * : :** ..:. . .::*:. *:.:* . .. . :: *:*:*..: : .: . :..: *:** :.*: . ", "identical_positions": 114, "similar_positions": 129, "identity": "27.87%" }, { "cls_id": "homologset.agr.RGD:620835", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88923-7", "uniprot_id": "AGRL2_RAT", "id": "O88923-7", "name": "Adhesion G protein-coupled receptor L2", "aln": "--MVSSGCRMRS----------LWFIMIISFSPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCVVVTGSDVFPDPCPGTYKYLEVQYECVPYMEQKVFVCPGTLKAIVDSPSIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESEAGKNVIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTTVSTTSSTSQRGPVSSTVAGPQEGSRGTKPPPAVSTTKIPPVTNIFPLPERFCEALEMKGIKWPQTQRGMMVERPCPKGTRGTASYLCMASTGTWNPKGPDLSNCTSHWVNQLAQKIRSGEN-AASLANELAKHTKG-TVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRAETLDCWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTDNIVLEVAVLSTEGQVQDFTFHLGFKGAF--SSIQLSANTVKQNSRNGLAKVVFIIYRSLGPFLSTENATVKLGAD-LLGRNSTIAVN-----------------SHVLSVSINKESSRVYLTDPVLFSMPHIDSDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIVYKDG--VHKLLLTVITWVGIVVSLVCLAICIFTFCFFRG--LQSDRNTIHKNLCINLFIAEFIFLIGIDKTQYTIACPVFAGLLHFFFLAAFSWMCLEGVQLYLMLV----EVFESEYSRKKYYYVAGYLFPATVVGVSAAIDSKSYGTLEACWLHVDNYFIWS-FIGPVTFIILLNIIFLVITLCKMVKHSNT--LKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFVN------EETVVMAYLFTAFNAFQGLFIFIFHCALQKKVRKEYAKCFRH------WYCCGGLPTESPHSSVKASTSRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQG-------------MTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPG------HSLNNTRDTSAMDTLPLNGNFNNS---YSLRKADYHDGVQVVD--CGLSLNDTAFEKMIISELVHNNLRGSNKTHNLELKLPVKPVIG----------GSSSEDDAIVADASSLMHG------DNPGLEFRH-KELEAPLIPQRTHSLLYQPQKKVKPEATD----SYVSQLTAEADEHLQSPNRDSLYTSMPNLRDSPYPESSPDMAEDLSPSRRSENED--------IYYKSMPNLGAGRQLQMCYQISR--------------------GNSDGYIIPINKEGCIPEGDVREGQMQLVTSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZZ7-1", "uniprot_id": "AGRL2_MOUSE", "id": "Q8JZZ7-1", "name": "Adhesion G protein-coupled receptor L2", "aln": "--MVSSGCRMRS----------LWFIIIISFSPSTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYSKMLVFVCPGTLKAIVDSPCIYEAEQKSGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETAYDKRAASNAFMICGVLYVVRSVYQDNESEAGKNTIDYIYNTRLSRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTTISTTSSASQRGPVSSTAAGPQDGSRGTKPPPAVSTTKIPPVTNIFPLPERFCEALDWKGIKWPQTQRGMMVERPCPKGTRGTASYLCMASTGTWNPKGPDLSNCTSHWVNQLAQKIRSGEN-AASLANELAKHTKG-HVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRAEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQVQDFKFPLGLKGLG--SSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLGAD-LMGRNSTIAVN-----------------SPVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDG--VHHLLLTVITWVGIVVSLVCLAICIFTFCFFRG--LQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYTIACPVFAGLLHFFFLAAFSWMCLEGVQLYLMLV----EVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTVQACWLHVDNYFIWS-FIGPVTFIILLNIIFLVITLCKMVKHSNT--LKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFVN------EETVVMAYLFTAFNAFQGLFIFIFHCALQKKVRKEYGKCFRH------WYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQG-------------MTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPAFNSPG------HSLNNARDTSAMDTLPLNGNFNNS---YSLRKADYHDGVQVVD--CGLSLNDTAFEKMIISELVHNNLRGGNKTHNLELKLPVKPVIG----------GSSSEDDAIVADASSLMHG------DNPGLEFRH-KELEAPLIPQRTHSLLYQPQKKVKPEATD----SYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDMAEDLSPSRRSENED--------IYYKSMPNLGAGRHLHMCYQISR--------------------GNSDGYIIPINKEGCIPEGDVREGQMQLVTSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95490-1", "uniprot_id": "AGRL2_HUMAN", "id": "O95490-1", "name": "Adhesion G protein-coupled receptor L2", "aln": "--MVSSGCRMRS----------LWFIIVISFLPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPY----IFVCPGTLKAIVDSPCIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETVYDKRAASNAFMICGVLYVVRSVYQDNESETGKNSIDYIYNTRLNRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTIISTTSTTSQKGPMSTTVAGSQEGSKGTKPPPAVSTTKIPPITNIFPLPERFCEALDSKGIKWPQTQRGMMVERPCPKGTRGTASYLCMISTGTWNPKGPDLSNCTSHWVNQLAQKIRSGEN-AASLANELAKHTKG-PVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRPEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQIQDFKFPLGIKGAG--SSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLGAD-FIGRNSTIAVN-----------------SHVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDG--VHELLLTVITWVGIVISLVCLAICIFTFCFFRG--LQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLV----EVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWS-FIGPVTFIILLNIIFLVITLCKMVKHSNT--LKPDSSRLENI------------------------KSWVLGAFALLCLLGLTWSFGLLFIN------EETIVMAYLFTIFNAFQGVFIFIFHCALQKKVRKEYGKCFRH------SYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQG-------------MTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPG------HSLNNARDTSAMDTLPLNGNFNNS---YSLHKGDYNDSVQVVD--CGLSLNDTAFEKMIISELVHNNLRGSSKTHNLELTLPVKPVIG----------GSSSEDDAIVADASSLMHS------DNPGLELHH-KELEAPLIPQRTHSLLYQPQKKVKSEGTD----SYVSQLTAEAEDHLQSPNRDSLYTSMPNLRDSPYPESSPDMEEDLSPSRRSENED--------IYYKSMPNLGAGHQLQMCYQISR--------------------GNSDGYIIPINKEGCIPEGDVREGQMQLVTSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GRP1-1", "uniprot_id": "A0AC58GRP1_DANRE", "id": "A0AC58GRP1-1", "name": "", "aln": "MWKAESPVRARMGCSEWKSLVLCGLVFVLTVVQSSDGFSRAAMPFGLVRRELSCEGYPIDLRCPGSDVIMIETANYGRTDDKICDADPFQMENINCYLPDAFKIMSQRCNNRTQCIVITGPDVFPDPCPGTYKYLEVQYECVPY----IFVCPGTLKAVGDPSFLYEAEQQAGSWCKDPLQAGDKVYFMPWTPYRTDTLIEYNSLDDFQNSRQTTTYKLPHRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINNANYHDTSPYKWGGKTDIDLAVDENGLWVIYATEQNNGMMVISQLNPYTLRFEATWETTYDKRSASNAFMICGVLYVVRSTYEDNESEVSKSLIDYMYNTKLNHGEYVDIHFPNQYQYIAAVEYNPRDNQLYVWNNFYILRYNLVFGPPDPAHAPPISEASTSPKVLKPTTTTTTTTQPKGQVTTITTTGTRAVNKTPKSPPVLPQTTTPPSLESFPPPERFCESVELRDILWPQTQRGMLVERPCPKGTRGTASYLCVLSTGTWNPKGPDLSNCTSHWVNQVAQKIRSGEN-AANLANELAKHTKG-AIFAGDISSTMRLMEQLVDILDAQLQELRPSEKDSTGRSFNKLQKRERTCRAYMKAIVDTVDNLLRPEALKSWRDMNTTEQTHAATMLLDTLEEGAFVLADNLMEPAIVKVPASNIILDVYVLSTDGQVQDFRFPQSGRGG---ISIQLSSNTVKLNSRNGVAKLVFALYKNLGQFLSTENATMKLGQE-VNGRNLSVAVN-----------------SDVIAASINKESSRVFISEPVIFTLEHIDMQHYYNSNCSFWNYSERTMMGYWSTQGCKLIHANKSHTTCSCSHLTNFAVLMAHRELLGADK--VQELLLSVISRVGIVVSLICLAMSIFTFCFFRG--LQSDRNTIHKNLCINLFIAELIFLIGIDMTEPKLACSIIAGILHYFFLASFAWMCLEGVQLYLMLV----EVFESEYSRRKYFYMAGYLLPAVVVGVSAAVDFRSYGTKKACWLRMDNHFIWS-FIGPVTFIIMLNLIFLLITMYKMMKHSTS--LKPDSSRLEHIN---------------YEDNKPFIKSWVMGGFALLCLLGLTWSFGLFFIS------ESSVVLAYLFTIFNTFQGMFIFTFHCLLQKKVRREYSKCLRH------TYCCSRITTESSHSSTKTSTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGKTKHKTISEPLEGMTGNYLLTNPLLRPQGTNNPYNTLLAETIVCNTPTVPVFHSPVTYRETRHSVTSGRDTNTFGTLPLNGNFNNS---YSLHN--YSDGMQVVD--CGLSLNDTAFEKMIISELVHNNLR------AAESRIGTKKGAG----------ISRGEE-PVVAETSSLVQVGGDSEMERLGLHHTHPRTLEAPLIPQRTHSLLYHTQERARPEAEASHPQSYIGQLPPPAETALPSPNRDSVYTSMPNLRDSPFSESSLDIVQDLSPSKNSPNED--------VYYKSMPNLGSGQQLHAYYQMSR--------------------DSSEGLIIPVSKDACVPEGDVREGQMQLVTSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GDD5-1", "uniprot_id": "A0AC58GDD5_DANRE", "id": "A0AC58GDD5-1", "name": "", "aln": "---MASSLWKRS--------LVLALLLTVIFLQPSEGFSRAALPFGLVRRELSCEGYPIDLRCPGSDVIMIETANYGRTDNKICDADPFQMDNINCYLPDAYKIVSQRCNNRTQCVVNTGSDVFPDPCPGTYKYLEVQYECVPY----IFICPGTLKAVGDPTLEFEAEQQSGAWCKDPLQAGDKIYFMPWTPYRTDTLIEYASLDDLRSGRQTTTYKLPHRVDGTGFVAYDGAIFFNKERTRNIVKFDLRTRIKSGEAIVASANYHDTSPYRWGGKTDIDLAVDERGLWVIYATEQNNGRIVLSQLNPYTLRFEATWETVYDKRSASNAFMVCGVLHVVRSTYEENESEASKSQIDYVYNTKLGQGEYVNILFPNKYQYIAAVDYNPRDNQLYVWNNFYILRYNLEFGPPDPDEEPTVSDDATSTLPPRRSTPAVLKTTLSLSFTQRPSLNSSISTDPLTEEHPEPPADPTAAASVPPASRRFCEPTEKRGISWPKTHRGLTVERPCPRGTRGIALFLCLTG-GVWNPKGPDLSNCTSHWVAQVAQKIRSGEN-AASLANELAHHTQG-SVFAGDVSSSVRLMEQLVDILDAQLQELKPDQKDSPGRSFNKRQKRERTCRAYMKAIVDTVDNLLRPEALKSWEDMNSTEQTHAATMLLDTLEEGAFVLADNLIEPAVVRMPAENIMLDVYVLSTDGQIQDFRFPQTSKRG---ATIQLSANMVKLNSKNGVAKLVFVLYKHLGHFLSTENATVRLMGD-GGLRNHTLTVN-----------------SHILSASINKESSRVFVSEPVIFTLEHLDTENYFNPNCSFWNYSERSMSGYWSTQGCKLLSTNKTHTTCSCSHLTNFAILMVHRDSHAGEGS-VHELLLTVITRLGIAVSLVCLAISIFTFCFFRG--LQSDRNTIHKNLCINLFIAELLFLVGINMTEPPIVCSVIAGVLHFFFLAAFSWMCLEGVQLFLMLV----EVFESEFSRRKYYYASGYLFPCVVVGISAAIDYKSYGTKKACWLRVDNHFIWS-FIGPVTFIILLNLIFLVVTMYKMVKHSMS--MKPDSSRLESIR------------------------SWVFGAFALLCLLCLTWSFGLLFLN------DSSVIMAYLFSIFNTLQGMFIFVFHCLLQKKVRKEYSKCFRQ------SQCCRTHPSEGPHSVNKSSASRSTARYSSATQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQG-------------MTGNYLLTNPLLRPHDTNNRYNNLLAETIVCSTPSPPAFHSPG-----QRSLSNSRDVSTMDTLPLNDNFNNS---YSLREDDYEDPAITCPTGCEIRLDDAAFEKMIISELVHNNLRPRRNQSSSKCQADRNSSPQENCADIDEGVGDRNECENAETDTSAMPLSSCHPAMELLLLNPNHREALEVPLLPQRTHSLIYASQKVIRPHKISR--DTQQDEGEVKKEDDSSPNNRDSLYTSMPNLKDSDLVIG--EEENSPCSSAQSETQE--------QCCKSLPDLGDGTPAMSYYQISA--------------------SLS------------LEAESANDGQMQLITSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7G7-4", "uniprot_id": "LPHN_DROME", "id": "A1Z7G7-4", "name": "Latrophilin Cirl", "aln": "----------------------------MLPTILSISYEHISLDLSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISA-------------------------AQTSTTTNRPSPPPWVLSNGPPIFGNGSGLIHPPGVG----AGAPPPPRLPTLPGVVGISGNPGLFNVPPQHTAVTHSTPSSSTTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQ-----LHHHHNHHGEDTASPTKPSSKLPAGGNATSP---SNTRILTGVGGSGTDDGTLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNINLNAAGMSGGDDESKLFCG--------------PTHARNLYWNMTRVGDVNVQPCPGGAAGIAKWRCVLMKRIPD----SGYDEYDDDISSTTPAPSGGDCLHNSSSCEPPVSMAHKVNQRLR---------------------NFEPTWHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFP------------DQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGK-GRHIQLSQPITLTLKHLKTENVTNPTCVFWNYIDH----AWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSIFCGFITIFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQTPKVNCYYLLSYGLSLSVVAISLVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLASVR------------------------FDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAG---STHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRGAGGVPASP---------SGSLHSRTAAASQVLFYPSYKKTKPGQPTGYPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQPEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .:.: :: :. : :*** : :.* .*** : ***** . .**: . . :* :*.: .::..** :: .* * :...:* ******:****.:*:*:. ::.: : * . : * . . **. .: . ... :** . .*: * . . ::* . : * . : . *:. : .*: * . : :: .:::* . * :* : . * : :. : * . .. .:*. .: .: : . * : * *.:. . :.:*: * . .. . . . . : .. **. : * .*:* ***::* * *: :: ::.. :. .:**:::. *.. ::.**: : :::: : : : : : : . ::** ::.:*.* .*** . *..* .:*. :* :.** ** ** .**:***.::. * ..**:*.* **.*. ... * : *:*. : **..*:.::** : * :*... . * . ** :: * * :::.*:.* . :: :::*: ::: *:. :: *..* **** :: **::**.* :*::::.*:*.******:** : . : . : :: :.* :.:: :.:.::*: :*.* ::* *.:*:..: : *: *::**:**: *: : * .:: .** :*:. :*:* *..: : *. : .: .: : :* .* :. **.:* .:* :* . * * * :::: *: ** .::: : : .:: * ::* : . : :** : : .*.:* ** .*. . ::: : : : .* * **:: *::** *** ::*:*:** * .*: * . .. : .:: : . *:..:.:: .: .:.:.:.. : : .:: . . *:*..* * * . : * : : .: . *. . :: . **. .: :. ** :: . :* . *:.: . : : . . :. : : . *: ** . .: : *: : . : : : : . :: :. . . .:. . .:* . :: . * : . . * .* . ", "identical_positions": 227, "similar_positions": 470, "identity": "12.15%" }, { "cls_id": "homologset.agr.RGD:620836", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z173-1", "uniprot_id": "AGRL3_RAT", "id": "Q9Z173-1", "name": "Adhesion G protein-coupled receptor L3", "aln": "MCPPQLFILMMLLAPVVHGGKHNERHPALAAPLRHAEHSPGGPLPPRHLLQQPAAERSTAHRGQGPRGTARGVRGPGAPGAQIAAQAFSRAPIPMAVVRRELSCESYPIELRCPGTDVIMIESANYGRTDDKICDSDPAQMENIRCYLPDAYKIMSQRCNNRTQCAVVAGPDVFPDPCPGTYKYLEVQYECVPYKVEQKVFLCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSDLERPPVRGISTTGPLGMGSTTTSTTLRTTTWNLGRSTTPSLPGRRNRSTSTPSPAIEVLD-VTTHLPSAASQIPAMEESCEAVEAREIMWFKTRQGQVAKQSCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGE-TAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPEN---TGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVN------------------SPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHS--DAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRG--LQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLV---EVFESEHS-RRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYIN------ESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCS---GKSTESSIGSGKTSGSR-TPGRYSTGSQSR--------IRRMWNDTVRKQSESSFITGDINSSASLNRGSYLPCIQACVTY--LEGLLNNARDTSVMDTLPLNG------NHGNSYSIAGGEYLSNCVQIIDRG----------------------------------YNHNETALEKKILKELTSNYIPSYLNN---------------------HERSSEQNRNMMNKLVDNLGSGS-----------EDDAIVLDDAASFNHEESLGLELIHEESD----APLLPPRVYSTDNHQPHHYSRRRLPQDHSESFFPLLTDEHTEDPQSPHR-----------DSLYT--SMPALAGVPAADSVTTSTQTEAAAAKGG--DAEDVYYKSMPN--------------------------LGSRNHVHPLHAYYQLGRGS-----------------------------------------------SDGFIVPPNKD-------------------------------GASPEGTSKGPAHLVTSL----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TS3-1", "uniprot_id": "AGRL3_MOUSE", "id": "Q80TS3-1", "name": "Adhesion G protein-coupled receptor L3", "aln": "MWPPQLLILTMLLAPVVHGGKHNERHPALAAPLRHAERSPGGALPPRHLLQQPAAERSTAHRGQGPRGAARGVRGPGAPGAQIAAQAFSRAPIPMAVVRRELSCESYPIELRCPGTDVIMIESANYGRTDDKICDSDPAQMENIRCYLPDAYKIMSQRCNNRTQCAVVAGPDVFPDPCPGTYKYLEVQYECVPYKVEQKVFLCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGPVHHGQVSYISPPIHLDSELERPPVRGISTTGSLGMGSTTTSTTLRTTTWNIGRSTTASLPGRRNRSTSTPSPAVEVLDDVTTHLPSAASQIPAMEESCEAVEAREIMWFKTRQGQVAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGE-TAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLNKLQKRERSCRAYVQAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLDTVEESAFVLADNLLKTDIVRENTDNIQLEVARLSTEGNLEDLKFPEN---MGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEAMSTNHSVIVN------------------SPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHS--DAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRG--LQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLV---EVFESEHS-RRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYIN------ESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCS---GKSTESSIGSGKTSGSR-TPGRYSTGSQSR--------IRRMWNDTVRKQSESSFITGDINSSASLNR----------------EGLLNNARDTSVMDTLPLNG------NHGNSYSIAGGEYLSNCVQIIDRG----------------------------------YNHNETALEKKILKELTSNYIPSYLNN---------------------HERSSEQNRNMMNKLVNNLGSGS-----------EDDAIVLDDAASFNHEESLGLELIHEESD----APLLPPRVYSTDNHQPHHYSRRRFPQDHSESFFPLLTDEHTEDLQSPHR-----------DSLYT--SMPALAGVPAADSVTTSTQTEAAAAKGG--DAEDVYYKSMPN--------------------------LGSRNHVHPLHAYYQLGRGS-----------------------------------------------SDGFIVPPNKD-------------------------------GASPEGTSKGPAHLVTSL----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAR2-1", "uniprot_id": "AGRL3_HUMAN", "id": "Q9HAR2-1", "name": "Adhesion G protein-coupled receptor L3", "aln": "MWPSQLLIFMMLLAPIIH--------------------------------------------------------------------AFSRAPIPMAVVRRELSCESYPIELRCPGTDVIMIESANYGRTDDKICDSDPAQMENIRCYLPDAYKIMSQRCNNRTQCAVVAGPDVFPDPCPGTYKYLEVQYECVPYKVEQKVFLCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDTLTEYSSKDDFIAGRPTTTYKLPHRVDGTGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYEDDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDFGPLDSRSGQAHHGQVSYISPPIHLDSELERPSVKDISTTGPLGMGSTTTSTTLRTTTLSPGRSTTPSVSGRRNRSTSTPSPAVEVLDDMTTHLPSASSQIPALEESCEAVEAREIMWFKTRQGQIAKQPCPAGTIGVSTYLCLAPDGIWDPQGPDLSNCSSPWVNHITQKLKSGE-TAANIARELAEQTRNHLNAGDITYSVRAMDQLVGLLDVQLRNLTPGGKDSAARSLN-------------KAMVETVNNLLQPQALNAWRDLTTSDQLRAATMLLHTVEESAFVLADNLLKTDIVRENTDNIKLEVARLSTEGNLEDLKFPEN---MGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEALSTNHSVIVN------------------SPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHS--DAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRG--LQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLV---EVFESEHS-RRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNI---------KSWVIGAIALLCLLGLTWAFGLMYIN------ESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCS---GKSTESSIGSGKTSGSR-TPGRYSTGSQSR--------IRRMWNDTVRKQSESSFITGDINSSASLNR----------------EGLLNNARDTSVMDTLPLNG------NHGNSYSIASGEYLSNCVQIIDRG----------------------------------YNHNETALEKKILKELTSNYIPSYLNN---------------------HERSSEQNRNLMNKLVNNLGSGR-----------EDDAIVLDDATSFNHEESLGLELIHEESD----APLLPPRVYSTENHQPHHYTRRRIPQDHSESFFPLLTNEHTEDLQSPHR-----------DSLYT--SMPTLAGVAATESVTTSTQTEPPPAKCG--DAEDVYYKSMPN--------------------------LGSRNHVHQLHTYYQLGRGS-----------------------------------------------SDGFIVPPNKD-------------------------------GTPPEGSSKGPAHLVTSL----------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7G7-4", "uniprot_id": "LPHN_DROME", "id": "A1Z7G7-4", "name": "Latrophilin Cirl", "aln": "-----------MLPTILS-------------------------------------------------------------------ISYEHISLDLSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISAAQTSTTTNRPSPPPWVLSNGPPIFGNGSG-------LIHPPGVGAGAPPPPRLPTLPGVVG----ISGNPGLFNVPPQHTAVTHSTPSS------------------STTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQ------LHHHHNHHGEDTASPTKPSSKLPAGGNATSPSN---------TRILTGVGGSGTDDG-------------------------------------------------TLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNIN--LNAAGMSGGDDESKLFCGPTHARNLYWNMTRVGDVNVQPCPGGAAGIAKWRCVLMKRIPDSGYDEYDDDISSTTPAPSGGDCLHNSSSCEPPVSMAHKVNQRLRN------------FEPTWHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFPDQRQREAMIMELL-----------HCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGKGR--HIQLSQPITLTLKHLK-TENVTNPTCVFWNY----IDHAWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSIFCGFITIFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQTPKVNCYYLLSYGLSLSVVAISLVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLAS------VRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAGSTHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRGAGGVPASPSGSLHSRTAAASQVLFYPSYKKTKPGQPTGYPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQPEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*..:: ::.: .: :: : :**. : :.* *** : ***** . .**:.. .:.* :*.: .::..** :: .*.*:*...:* ******:****.:*:*:. ... *. * .. : .: .. * . : . .* * **. . *:*.* *::. * . . * .* : ..*. *: : * :..: . : :: .:::*: . * :* : * *: .: ** * . **. . ..* * : * : ** . *: * : . ::: *: . : . . . * *.* : . . * . .. .. * . :. .: * . . *. .. .. :.:. . . .: .:* : *.* ***::* * *:*:: :::. : : .**.:::* * .: *. . : * *. :: :: *. :: * :: :.:*:* .***: . *.:* **...**:*.** ** :* .**:***.::: * ::..** *.* *.*: ..: **:. .. *:*. :* :*...* :*:.*. ::.* . *... :.* :. ..::.*:. * **:*::.* :: *::*:.:*:**:* :*: **.* **.* : **::** * :**:**:.**********:** *: :: ::.* : :: ::.* :.:* ::*.::*: :*.* ::* *.:*:..: :.*:. *****:**::*: .* *..:: :** :*:. :*: *..: * *. ::* ::: : : :**:.**:. :**:* .:* :* :. * * . :::: : ..*:::: .* : : :: :.: :: .: : : ::.:* **. .*. . :*:. ::: : .* * **:* *::**:***: ::*:*:** * :* *. :.:::**.** .:*. *.* .: * *: .. :*. ::*. . ** * .*: : * *: . :* ..: .* .*... * *.. :* . : :: * :* * .. : * .. *. *.*:: .: :: .: .* : . : *: :::::.* : :*::.: * . . : :: : * ** .*:: : * ::: : * * :* *: *. *: * .. :.: :. ::: : * *.::** :*: . :.**.: : *: * : .*.. :**:.* *: * *:. * * : : ", "identical_positions": 307, "similar_positions": 528, "identity": "15.99%" }, { "cls_id": "homologset.agr.RGD:620837", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70513-1", "uniprot_id": "LG3BP_RAT", "id": "O70513-1", "name": "Galectin-3-binding protein", "aln": "--MALLWLLSVFLLVPG--------TQGAKDGDMRLVNGASASEGRVEIFYRGRWGTVCDNLWNLLDAHVVCRALGYENATQALSRAAFGPGKGPIMLDEVECTGNESSLANCSSLGWMVSHCGHEKDAGVVCSNDSRGIHILDLSG----ELPDALGQIFDSQQDCDLFIQVTGQ-GHGDLSLCAHTLILRTNPEAQALWQVVGSSVIMRVDAECMPVVRDFLRYFYSRRIEVSMSSVKCLHKLASAYGATELQGYCGRLFVTLLPQDPTFHTPLELYEYAQATGDSVLEDLCVQFLAWNFEPLTQAEAWLSVPNALIQALLPKSELAVSSELDLLKAVDQWS--TATGASHGDVERLVEQIRFPMMLPQELFELQFN-LSLYQGHQALFQRKTMEALEFHTVPLKVLAKYRSLNLTEDVYKPRLYTSSTWSSLLMAGAWSTQS----YKYR---QFYTYN-----YGSQSRYSSYQNFQTPQHPSFLFKDKLISWSATYLPTIQSCWNYGFSCTSDELPVLGLTTSSYSDP-TIGYENKALILCGG-YSVVDVTTFIGSKAPIPGTQETNSSKTPSLFPCASGAFSSFRVVIRPFYLTNSTDTE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07797-1", "uniprot_id": "LG3BP_MOUSE", "id": "Q07797-1", "name": "Galectin-3-binding protein", "aln": "--MALLWLLSVFLLVPG--------TQGTEDGDMRLVNGASANEGRVEIFYRGRWGTVCDNLWNLLDAHVVCRALGYENATQALGRAAFGPGKGPIMLDEVECTGTESSLASCRSLGWMVSRCGHEKDAGVVCSNDTTGLHILDLSG----ELSDALGQIFDSQQGCDLFIQVTGQ-GYEDLSLCAHTLILRTNPEAQALWQVVGSSVIMRVDAECMPVVRDFLRYFYSRRIEVSMSSVKCLHKLASAYGATELQDYCGRLFATLLPQDPTFHTPLDLYAYARATGDSMLEDLCVQFLAWNFEPLTQSESWSAVPTTLIQALLPKSELAVSSELDLLKAVDQWS--TETIASHEDIERLVEQVRFPMMLPQELFELQFN-LSLYQDHQALFQRKTMQALEFHTVPVEVLAKYKGLNLTEDTYKPRLYTSSTWSSLVMASTWRAQR----YEYNRYNQLYTYG-----YGSVARYNSYQSFQTPQHPSFLFKDKQISWSATYLPTMQSCWNYGFSCTSNELPVLGLTTSSYSNP-TIGYENRVLILCGG-YSVVDVTSFEGSKAPIPTALDTNSSKTPSLFPCASGAFSSFRVVIRPFYLTNSTDMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08380-1", "uniprot_id": "LG3BP_HUMAN", "id": "Q08380-1", "name": "Galectin-3-binding protein", "aln": "--MTPPRLFWVWLLVAG--------TQGVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSR----ELSEALGQIFDSQRGCDLSISVNVQ-GEDALGFCGHTVILTANLEAQALWKEPGSNVTMSVDAECVPMVRDLLRYFYSRRIDITLSSVKCFHKLASAYGARQLQGYCASLFAILLPQDPSFQMPLDLYAYAVATGDALLEKLCLQFLAWNFEALTQAEAWPSVPTDLLQLLLPRSDLAVPSELALLKAVDTWS--WGERASHEEVEGLVEKIRFPMMLPEELFELQFN-LSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTSPTWSAFVTDSSWSARKSQLVYQSRR-GPLVKYSSDYFQAPSDYRYYPYQSFQTPQHPSFLFQDKRVSWSLVYLPTIQSCWNYGFSCSSDELPVLGLTKSGGSDR-TIAYENKALMLCEG-LFVADVTDFEGWKAAIPSALDTNSSKSTSSFPCPAGHFNGFRTVIRPFYLTNSSGVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24JV9-1", "uniprot_id": "L3BPA_DANRE", "id": "Q24JV9-1", "name": "Galectin-3-binding protein A", "aln": "MIMYIIWALLFIPVSAQQWTLFDEQAKPKREGRVRLVG-GLPSSGRVEVYHDGQWGTVCDDGWDLAEAQVVCRQLGFPGAVSVASGGQYGEGSGPIWLDDMNCKGSESILSECCFKGWGVNDCTHQEDAGVVCDTGTNATNIRQISVDNSLGLSDDLGLLFDSEDGCDFIIAVQDLGEEAELTLCVHRVILMMYPELNITNDTR--NLTVDVSQTCQSHVSALIRYLYTRQIDVSATSAQCLYQLAFIFGVQRLMEDVGRVFTALIPEDNTFQTPVSMYEYGLRTGDLVLQENVLQYLSWNCEFLISSPVWSTVSFEMMDALLQRSDLIVKDEAVLLEALERWIQDKGDQISSDKQASLLSHIRFLLIPVDKLYDIQFSSSALYQNNEKLYLTGLLRGFEFNALPFSKIR--NQIDNASSEYLPRIYTGDEWSVFINDTTVSSPYYN--YNY-----YGQSN------------RIQTFFTS-AHPSALYKDQKVQWQAQVFLTLQECSNYGVSCNTLPVARFYGYSNQYSYSNIISYNNRLILTCKNQNNVFHVQEFKNDVAVIP-------TNSSMGLPNPCPDDYSFRFVVRPQYI-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NY73-1", "uniprot_id": "L3BPB_DANRE", "id": "Q6NY73-1", "name": "Galectin-3-binding protein B", "aln": "--MLLLWPLLFLQVSALRRTLFDRPKQLMQEGRVRLVG-VIPSSGRVEVYHDGQWGTVCDDGWDLAEAQVVCRQLGFPGAVSVATGGQYGEGSGRVWLDDMNCKGSESLLSECSFKGWGVSDCTHKEDAGVICAPGKNTTSIRQMSVDNSLGLSDDLGLLFDSEDGCDFTIAVRDLSEEAELTFCVHRVILMIYPELNLTHDTR--NITVDISQTCHTHVPRFLRYLYTRQIDVSTTSAQCLHQLAFIFGVQKLMEDVGRVFTALIPEDNTFQTQVSMYEYGVRTGDLVLQENVLQYLSWNCEFLISSPVWSTVSFDMMDALLQRSDLIVKDEAVLLEALERWIQDKGDQISSDKQVSLLNHIRFLLIPVDKLYDIQFSSSALRQSNEKLYLTGLLRGFQFNALPFSKIR--DQVVKLSGNYIPRIYIGDEWSLGLNVSTVNNPHYNP-YQYGYDQRYGQSN------------RIEKYLSTPAHPSAVYRGQMIQWQAQVFRSVQDCRNSGISCNSVPLVRFLATSSQYSYSSTIRYNNRLVLTCKNQNNVFHVQDFKNNMAVIP-------TNSSMGLPNPCPDDYSFRFVVRPQYI-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : . : .:* :**.. ...****::: *:******: *:* :* **** **: .*... . :* *.* : **:::*.*.*: *:.* ** . * *:.****:* . ::* *.: ** :***: .**: * * * :* * :** * : . .: : :. * . * ::**:*:*:*::: :*.:*:::** :*. .* . :*. *:*:* :*: :.:* *. *** :*:. :*:*:** * * .: * :*. ::: ** :*:* * .* **:*:: * * . *:.::** :: ::*:::**. :* .:: *: :..::*:::*.. : : .. * **:* . ** : : *: . : : *** :::.: :.*. : ::*.* * *.**.: : : .. * * *:*: :: * . * .* * . * ** :::. :* .. .** *:** *: ", "identical_positions": 149, "similar_positions": 183, "identity": "24.59%" }, { "cls_id": "homologset.agr.RGD:620838", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHK6-1", "uniprot_id": "I13R2_RAT", "id": "Q8VHK6-1", "name": "Interleukin-13 receptor subunit alpha-2", "aln": "---MALMAVNTRCLCLFLLCTITGHS----LEIKVNPPQDFEILDPGLLGYLYLQWKPPVVMDNFKECKLEYELKYRNVDSDSWKTIITRNLIYKDGFDLNKGIEGKIRTHLSEHCTNGSEVQSPWTEASYGIADEGSLGTKIQDMKCIYYNWQYLVCSWKPGKTVHSDTNYTMFFWYEGLDHALQCADYLQDNEKNVGCKLSNLDSSDYKDFFIRVNGSSKLEPIRSSYMVFQLQNIVKPLPPEFLHISVENSIDIRMKWSTPGGPIPPSCYTYEIVVR--------EDDISWESATDKNDMKLKRRANESEDLCFFVRCKINIYCADDGIWSEWSEEECWEG-YTGPDSKIVFIVPVC--LFFIFLLLLLCLIVEKEDPEPTLSLHVDLNKEMYAYEETLC----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88786-1", "uniprot_id": "I13R2_MOUSE", "id": "O88786-1", "name": "Interleukin-13 receptor subunit alpha-2", "aln": "-----MAFVHIRCLCFILLCTITGYS----LEIKVNPPQDFEILDPGLLGYLYLQWKPPVVIEKFKGCTLEYELKYRNVDSDSWKTIITRNLIYKDGFDLNKGIEGKIRTHLSEHCTNGSEVQSPWIEASYGISDEGSLETKIQDMKCIYYNWQYLVCSWKPGKTVYSDTNYTMFFWYEGLDHALQCADYLQHDEKNVGCKLSNLDSSDYKDFFICVNGSSKLEPIRSSYTVFQLQNIVKPLPPEFLHISVENSIDIRMKWSTPGGPIPPRCYTYEIVIR--------EDDISWESATDKNDMKLKRRANESEDLCFFVRCKVNIYCADDGIWSEWSEEECWEG-YTGPDSKIIFIVPVC--LFFIFLLLLLCLIVEKEEPEPTLSLHVDLNKEVCAYEDTLC----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14627-1", "uniprot_id": "I13R2_HUMAN", "id": "Q14627-1", "name": "Interleukin-13 receptor subunit alpha-2", "aln": "---MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIR--------EDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFG--FILILVIFVTGLLLRKPNTYPKMIPEFFCDT--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UYQ0-1", "uniprot_id": "A0A8N7UYQ0_DANRE", "id": "A0A8N7UYQ0-1", "name": "", "aln": "MLLLNRFSVWLSAFAVLLLTQPISTSEVMACGAAVDPPANIEITDPGFLGYLNIQWTRPASLQNLTGCTVRYQLRYFDTYEERWRSVRTVKLTYAAQFDLEKPVKLRILTVLKCACTNGTEVQGEETETVYTPEPTGLAGSRIRDFHCIYYGKEHMECTWKSGPVQPPNSEHYLYYWHREMEETKECPEYIVSSNNERGCRFPRQSLLEFSKFNMCVNGSSSTGSLRPAYFSIEIQNYVKPAAVSSLDV-LETDGRLKLEWAPPSGQVPEHCLDYEVESSTLMANGKELKQTEILENLDLGTSYELPREAESKKTCFNLRSKVNMYCADGGFWSDWSQTKCTVKPTLNYRLLDLVMIGTAGVIIFCLSLWILTRICIKPCSKKDVIYTLYKQKVNENMPSIFSPIFK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: :*: . : *:** ::** *** **** :** * ::::. *.:.*:*:* : .: *::: * :* * ***:* :: :* * * ****:***. *: * * ::::*:.*:**. ::: *:**.* :::: :::*:. ::.: :* :*: . :: **::. . ::..* : *****. .:*.:* :::** *** . * . *.. ::::*: * * :* * **: .: . *:.. ** :*.*:*:**:*.*:**:**: :* . . : ::: : : : : * . : . :. ", "identical_positions": 92, "similar_positions": 126, "identity": "22.6%" }, { "cls_id": "homologset.agr.RGD:620839", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U1J1-1", "uniprot_id": "TFPT_MOUSE", "id": "Q3U1J1-1", "name": "TCF3 fusion partner homolog", "aln": "MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGDSGLRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFLMRVLDSYGDDYRDSQFTIVLEDDGSQGTDVPTPGNAENEPPEKEGLSPSQRTTATLDPTSPAPGEGPSGRKRRRAPR----VGASLTPELAPVQVGAEGWGQGVIKVEEDFGFEADEALDSSWVSREPDKLLPYPTLASPPFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JMG6-1", "uniprot_id": "TFPT_RAT", "id": "Q9JMG6-1", "name": "TCF3 fusion partner homolog", "aln": "MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGDSGLRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFLMRVLDSYGDDYRDSQFTIVLEDDGSQGTDVPTPGNVENEPPEKEGLSPPQRTTATLDPSSPAPGEGPSGRKRRRAPR----AASSLTPELAPVQVGAEGWGQGVIKVEEDFGFEADEALDSSWVSRGPDKLLPYPTLASPPFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C1Z6-1", "uniprot_id": "TFPT_HUMAN", "id": "P0C1Z6-1", "name": "TCF3 fusion partner", "aln": "MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGGSGLRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFLMRVLDSYGDDYRASQFTIVLEDEGSQGTDAPTPGNAENEPPEKETLSPPRRTPAPPEPGSPAPGEGPSGRKRRRVPRDGRRAGNALTPELAPVQI----------KVEEDFGFEADEALDSSWVSRGPDKLLPYPTLASPASD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****************************************************.****************************************************************************** *********:******.*****.******** ***.:**.*. :* ***************.** .. :*********: ********************* *************. *", "identical_positions": 227, "similar_positions": 15, "identity": "86.31%" }, { "cls_id": "homologset.agr.RGD:62084", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17267-1", "uniprot_id": "IF_RAT", "id": "P17267-1", "name": "Cobalamin binding intrinsic factor", "aln": "MAWLS----FYLLNVLWAVAGTSTRAQRSCSVPPDQQP--------------WVNGLQLLMENSVTESDLPNPSILIAMNLAS---------TYNLEAQKLLTYQLMASDSADLTNGQLALTIMALTSSCRDP------------------------------------------------------GSKVSILQKNMESWTPSNLGAE-----------SSSFYGPALAILALCQKNSEATLPIAVRFAKTLMMESSPFSVDTG----------------------AVATLALTCMYNRIPVGSQENYRDLFGQALKVIVDNISLRIKAD------------------------------GIIGDIYSTGLAMQALSVTPEQPTKEWDCEKTMYTILK--EIKQGKFQNPMS-----------IAQILPSLKGKTYLDVPQVTCGPDHEVPPTLTDYPTP---------VPTSISNITVIYTINNQLRGVDLLFNVTIEVSVKSGSVLLAVLEEAQRRNHMFKFETTMTSWGLIVSSINNIAENVKHKTYWEFLSG-------KTPLG-----EGVAYYIPFNYEHITANFTQY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52787-1", "uniprot_id": "IF_MOUSE", "id": "P52787-1", "name": "Cobalamin binding intrinsic factor", "aln": "MAWLT----LYLLSVLWAVAGTSTRAQSSCSVPPDQQP--------------WVDGLQALMENSVTDSDFPNPSILIAMNLAG---------AYNVEAQKLLTYQLMASDSADLTSGQLALTVMALTSSCRDP------------------------------------------------------GSKVSTLLKKMENWSPSSPGAE-----------SSAFYGPGLAILALCQKSSEATLPIAVRFAKTLMMEPSPFNVDTG----------------------AVATLALTCMYNKIPVGSQENYRDLFGQALKAIVEKISLRIKAD------------------------------GIIGDIYSTGLAMQALSVTPEQPTKKWDCEKTMHTILN--EIKQGKFQNPMS-----------IAQILPSLKGKTYLDVPQVTCGPDHEVPPTLTDYPTP---------VPTSVSNITVIYTINNQLRGVDLLFNVTIEVSVKSGSVLLAVLEEAQRKNSMFKFETTMTSWGLIVSSINNIAENVNHKTYWEFLSG-------KTPLD-----EGVAYYIPFNHEHITANFTQY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27352-1", "uniprot_id": "IF_HUMAN", "id": "P27352-1", "name": "Cobalamin binding intrinsic factor", "aln": "MAWFA----LYLLSLLWATAGTSTQTQSSCSVPSAQEP--------------LVNGIQVLMENSVTSSAYPNPSILIAMNLAG---------AYNLKAQKLLTYQLMSSDNNDLTIGQLGLTIMALTSSCRDP------------------------------------------------------GDKVSILQRQMENWAPSSPNAE-----------ASAFYGPSLAILALCQKNSEATLPIAVRFAKTLLANSSPFNVDTG----------------------AMATLALTCMYNKIPVGSEEGYRSLFGQVLKDIVEKISMKIKDN------------------------------GIIGDIYSTGLAMQALSVTPEPSKKEWNCKKTTDMILN--EIKQGKFHNPMS-----------IAQILPSLKGKTYLDVPQVTCSPDHEVQPTLPSNPGP---------GPTSASNITVIYTINNQLRGVELLFNETINVSVKSGSVLLVVLEEAQRKNPMFKFETTMTSWGLVVSSINNIAENVNHKTYWQFLSG-------VTPLN-----EGVADYIPFNHEHITANFTQY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4K2-1", "uniprot_id": "Y3556_DROME", "id": "Q9W4K2-1", "name": "Uncharacterized protein CG3556", "aln": "MLSLSSPPWLLLLVLFFFANGSATVVSLAENVTLATLPSTSPISVSFSTTSSVVAPISTELENQTASSSNLNTNNEASDEQTGNSNSNTSSHSRNINGLPSSNSNIDNANSNSSSVSSLSTTTSAISGVDQQESLILATPTALNGSGTPPEHQTIGQAPPTKGEQEAILRALDWLKEKRASDYGWGNDTHVVILAKELSGGRDPNDSVDGHVQVIQELEDTLSVKEMEIEILAMLDRHHTLPKPLDLDKLARYVLALGSLCKDPKHFHGHDLVATLQHHEPAQDIEFALTTLSACSSAAHVRKRQIRRLLDIASGVTDQSVDAIAMVILALRCIVTDHRHRHLQHFVRRPARGLATLQDQRGSFGSLRSTALAMQALQDLEYDPAGHWNRTAASRYILSRQRADGGWSEEPLQDGQEPDIGVGLTADIILALGWKGLGAVRALQCDHVIRESSDPTENGEPKLAVPFGLSSSAEESDAKNISYTYTLWVGSNVTESFSLSLVSPKNTSFFKAMTQAAEMDPRFIFEAREWPNGHYVHTLYGKKEEPRGYHYWLLYRLPELPDPNNTPGNQLIAPVGVDELMVEDGEHYLYWYKKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: : ** ::: . *::* .. : .*. * * :. :**..:.* *.. : : :. : *::. . :: ::. . : ..*. * *::. :: . :* * :::.. .. ..: : :. : ***: :: . *: : : ..: *. *::**: . :: . . .: . . . *: *:: * * :*.: **.******. . .*: : **. . . * .:*:. *:*: :* * * : *. . . .. * .:. *: . * . * :: . ::.: ..: :: .: :* . : * **: . * * :: . *: . ** : ** . ** : : ** :.: ", "identical_positions": 69, "similar_positions": 152, "identity": "11.6%" }, { "cls_id": "homologset.agr.RGD:620840", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31943-1", "uniprot_id": "HNRH1_HUMAN", "id": "P31943-1", "name": "Heterogeneous nuclear ribonucleoprotein H", "aln": "--------------------------------------MMLGTEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRP--GAGRGYNSIGRGAGFERMRRGAYGGGYG---GYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLP--YRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMG------GMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQE--------------------------------------------------------------------------NSSDFQSNIA----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35737-1", "uniprot_id": "HNRH1_MOUSE", "id": "O35737-1", "name": "Heterogeneous nuclear ribonucleoprotein H", "aln": "--------------------------------------MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRP--GAGRGYNSIGRGAGFERMRRGAYGGGYG---GYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLP--YRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMG------GMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQE--------------------------------------------------------------------------NSSDFQSNIA----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VHV7-1", "uniprot_id": "HNRH1_RAT", "id": "Q8VHV7-1", "name": "Heterogeneous nuclear ribonucleoprotein H", "aln": "--------------------------------------MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTRE-GRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSEEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRP--GAGRGYNSIGRGAGFERMRRGAYGGGYG---GYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLP--YRATENDIYNFFSPLNPVRVHIETGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMG------GMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQE--------------------------------------------------------------------------NSSDFQSNIA----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1QFJ8-1", "uniprot_id": "F1QFJ8_DANRE", "id": "F1QFJ8-1", "name": "", "aln": "------------------------------------------MADDEGFVVRVRGLPWSCSAEEVSRFFSGCKISSNGSAIHFTYTRE-GRPSGEAFVELESEDDLKIAVKKDRESMGHRYVEVFKSNNVEMDWVLKHTGPNCPETEGDGLVRLRGLPFGCSKEEIVQFFSGLEIVPN--GITLPVDFQGRSTGEAFVQFASQDIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYEPPRKGMGMQRPGPYDRPS-GGGRGYNGMSRGGSFDRMRRGGYGG----------------------------------GVSDGRYGDGG-NFQSTTGHCVHMRGLP--YRATEPDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGGSN--------------------GGYGGQMMG------GMG--NQSSYG-HGGQQMGGGYTGGYSSQSSMGGYNDYNSQGG-----------------------------------------------------------------------MSNSYYGGSRGSVGMNGMGGGWGM---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGH5-1", "uniprot_id": "Q9VGH5_DROME", "id": "Q9VGH5-1", "name": "", "aln": "MSNADVQFNYGQQGNGDNFNDDSNQQQDEDDQYNEDGGGKIENVGESPKFVRLRGLPWSATHKEILDFLENVNVTNGSAGIHLVTSRVDGKNTGEAYVEVASQEDVEEARKLNKASMGHRYIEVFTATPKEAKEAMRKISGHG----TAFVVKLRGLPYAVTEQQIEEFFSGLDIKTDREGILFVMDRRGRATGEAFVQFESQDDTEQALGRNREKIGHRYIEIFRSSIAEMKRATGAGGG--VGGRPGPYDIRDRGANRGGNDFG-GGRNDWGNNGNFGVGANNMLGFNNLPSLMNSGNFGNNQGGNNGNFGNNSGPSNFGNFGGGNNGGNSGNFGNDSGNSGNFGNFGNNGGGNFGGNNNGGGGFNSGNNFNSPGGVNNFGNNGGSNFGGNGGGGFNNGGNFVSSSGVGNFGPIGGGRNNNNGNFGNSGFGNFGGNNNVGSNFGGGNNGGGGGFNNGSNFGGGNSMGGGGNFGPIGGGRGNDIEYYTIHMRGLPYTSFENDVFKFFEPIRPANVRINYNKKGLHSGTADAYFDTYEDSQVAMKRHREQMGSRYIELFYDGKTRGLNGGEHGGGNGGGGMGNNGGGNFSRRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .*::******.: .*: *:.. :: ... .*:: :* *: :***:**: *::::: * * :: :*****:***.:. * . .::: . : .*:*****:. ::::* :*****:* .: ** : :* :**:******** **: :*:** :::*:*********:** **:: . ****** *..** *.:. *. : ..* :* . .. . ** . ..:*: : * . : : . *. * :: * : . .* .: . . ... . . * .:*. .. * . . .. :* * * * *.:* . .*.: ..:.. * . ... . .. . ", "identical_positions": 106, "similar_positions": 139, "identity": "17.88%" }, { "cls_id": "homologset.agr.RGD:620841", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70196-1", "uniprot_id": "PPCE_RAT", "id": "O70196-1", "name": "Prolyl endopeptidase", "aln": "--------------------------------------------MLSFQYPDVYRDETSVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSL--EGEARVFLDPNTLSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFTCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLCYHVLGTDQSEDVLCAEFPDEPKWMGGAELSDDGRYVLLSIWEGCDPVNRLWYCDLQQGSNGINGILKWVKLIDNFEGEYDYITNEGTVFTFKTNRNSPNYRLINIDFTDPDESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLRNVKNILQLHDLTTGALLKTFPLDVGSVVGYSGRKKDSEIFYQFTSFLSPGVIYHCDLTREELEPRVFREVTV--KGIDASDYQTIQVFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTTSKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKFTIGHAWTTDYGCSDSKQHFEWLLKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGPGKPTAKVIEEVSDMFAFIARCLNIEWIQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUR6-1", "uniprot_id": "PPCE_MOUSE", "id": "Q9QUR6-1", "name": "Prolyl endopeptidase", "aln": "--------------------------------------------MLSFQYPDVYRDETSVQEYHGHKICDPYSWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSL--EGEARVFLDPNTLSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFTCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLCYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIWEGCDPVNRLWYCDLQQEPNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRNSPNYRLINIDFTDPDESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNILQLHDLTTGALLKTFPLDVGSVVGYSGRKKDSEIFYQFTSFLSPGVIYHCDLTKEELEPMVFREVTV--KGIDAADYQTIQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKFTIGHAWTTDYGCSDTKQHFEWLLKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIEWIQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48147-1", "uniprot_id": "PPCE_HUMAN", "id": "P48147-1", "name": "Prolyl endopeptidase", "aln": "--------------------------------------------MLSLQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSL--EGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRQSPNYRVINIDFRDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNILQLHDLTTGALLKTFPLDVGSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTV--KGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGILAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLVKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNVDWIP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKW5-1", "uniprot_id": "Q9VKW5_DROME", "id": "Q9VKW5-1", "name": "Prolyl endopeptidase", "aln": "MHTIFRGPLLYRRICQIVVPKTLPRNYIHRELPSNLTRAMPSTLSAKLAYPVARKDESVAEDFHGTQIKDVYRWLEDPDSTETEEFVNAQNSISRPFLENGEEWKKLNTKLTKLWNYPKYGCPMRYGNYYYYFMNTGLQNQSVMYQQKSLGDESESKVFLDPNTLSEDGTIALTQKAFSEDGKYMAYGLSESGSDWIKILIRDAETGKDLSEVLEKVKFSEISWTKDNKGFFYGRYPDQDGKTDGSETKQNENQKLYYHRVGESQDKDTLVVEFPEEPSWRIQSTVSDCGKYLILAIVKDCR-DNIVFYADLTPGAE-ITSKLNVKKIVEKFEADYDYITNEGSKIFFRTNKNAPNYQVIAIDFNNSAEDKWETLIAEHKSDVLDWVKCVDNDKLLVCYIRDVKSVLQVNSLKDGTLLREFDLDIGTIVGTSGEKKYSEIFYNFSSFLNPGSIYRYDFKTPDKSPSVFREIKLNLEGFRREDYAVEQIFYKSKDGTKVPMFIIRKKRDSVE-PRPCLLYGYGGFNISMLPSFGLSGLMFIDTFDGVLAYPNLRGGGEYGEKWHNGGRLLNKQNVFDDFQAAAEYLIENKYTTKDRLAIQGGSNGGLLVGSCINQRPDLFGAAVAQVGVMDMLRFHKFTIGHAWCSDYGNPSEKEHFDNLYKFSPLHNVHTPKGAETEYPSTLILTADHDDRVSPLHSLKFIAALQEAVRDSEFQKNPVLLRVYQKAGHGAGKPTSKRIEEATDILTFLSKSLNVDIVNV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9P5-1", "uniprot_id": "Q9V9P5_DROME", "id": "Q9V9P5-1", "name": "Prolyl endopeptidase", "aln": "----------------------MSRSDALVQSPTDLSRSV-EEASLRIVYPEARKDGRFEEMIHGYKIKDVYRWLEDPDSVDTQQFVNAQNNISQSFLERSAERENINSKLTKLWNFPKYGCPMRHGNYYYFFKNTGLQNQSVLMQQKTL--ESPESIFLDTNSISSDGTTAISHIKFSEDGAFMAYGLSESGSDWNKIRIRNTKEGIDLPEILEKVKFSNVSWTKDSKGFFYGRYTDQDGIFDGSETKLAENQKLYYHLLGESPHQDILIAEFPEHPSWRFKTDISDCGKYLILSISHTVR-DNMLYYAELGSEEK-NAFQLELKPIVDKFEADFDYITNEGSNLYFHTNKDAPNYRVIVIDVNNPAEEHWTTPIPEHKKDVLEWAKCVDGNKLVVCYNCDVKHILQARDLSTGKLIRQFGLDIGSINGISGKKSNSEIFYGFSSFLSPGIIFYYDFAKPSEKPTVLREISLNLEGFSRDNYSVEQVFYKSTDDTDIPMFIVQRKRDIAE-PRPCLLYGYGGFNYSLMPSFGILSLMFMDTFDGVLAFPNLRGGGEYGMEWHNGGRMLSKQNVFNDFQAAAEFLTKNNYTTKDRLAIQGASNGGLLVGACINQRPDLFGAAVAQVGVMDMLRFHKFTIGHAWCSDYGNPDEKVHFANLIKFSPLHNVHIPLNPNQEYPSTLILTADHDDRVSPLHSYKFVAALQEAVRYSEYQLNPILLRVYTKAGHGAGKPTKMRISEATDIITFFKKTLNVDCINL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** . :* : ** :* * * ******* :*: **:***.*: .***. : ::*:*:::***.* :: *: *::* ******* *: *.:* *. :***.* :*.*** *: ***** ::***** ***** .* : ... . :*.::**:***: ::**:*.**:**. *.:*** **:**. :*** ** :* . :* * .***:.*.* : :** *:*::*:* . * ::*.:* . *: ::::**.::**:****: : *:**:::***::* **. :. *.:* . :.**:.***:* ** .: *::** :** :** ..*. * *:: * **:*:: * **.*. :**** *:***.** *: *: . .* *:**:.: :*: :* . *:** *.*.*.:****:::* : .:*.:******** *: *.:.: *:*: :.*:** .*:******* **:** : .*** *:***.***:* :: **: .**:*:*.*******.:* ********..:*********:***:****** :*** .. * ** * *:******: * : :*** *:********* **** **:*:** * *. * **:*::* *****.**** *.*.:*:::*: : **:: : ", "identical_positions": 326, "similar_positions": 208, "identity": "42.95%" }, { "cls_id": "homologset.agr.RGD:620842", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZP1-1", "uniprot_id": "GEMI2_RAT", "id": "Q9QZP1-1", "name": "Gem-associated protein 2", "aln": "-----------MAWVPAESAVEELMPRLLPVEPCDLTEGFDPSVPPRTPQEYLRRVQIEAAQCPDVVVAQIDPKKLKRKQSVNVSLSG-CHPAPEGYSPTLQWQQQQVIQFSSVRQSVHKHRNHWKSQQLDSNVTMPKSEDEEGWKKFCLGERLCAEGATGPSTDESPGIDYVQVGFPPLLSIVSRMNQATITSVLEYLSNWFGERDFTPELG------RWFYALLACLEKPLLPEAHSLIRQLARRCSEVRLLVGSKDDERVPALNLLICLVSRYFDQRDLADEPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQQ4-1", "uniprot_id": "GEMI2_MOUSE", "id": "Q9CQQ4-1", "name": "Gem-associated protein 2", "aln": "-----------MAWVPAESAVEELMPRLLPVEPCDLTEGFDPSVPPRTPQEYLRRVQIEAAQCPDVVVAQIDPKKLKRKQSVNISLSG-CQPAPEGYSPTLQWQQQQVAHFSTVRQSVHKHRNHWKSQQLDSNVAMPKSEDEEGWKKFCLGERLCAEGATGPSTEESPGIDYVQVGFPPLLSIVSRMNQTTITSVLEYLSNWFGERDFTPELG------RWFYALLACLEKPLLPEAHSLIRQLARRCSEVRLLVGSKDDERVPALNLLICLVSRYFDQRDLADEPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14893-1", "uniprot_id": "GEMI2_HUMAN", "id": "O14893-1", "name": "Gem-associated protein 2", "aln": "MRRAELAGLKTMAWVPAESAVEELMPRLLPVEPCDLTEGFDPSVPPRTPQEYLRRVQIEAAQCPDVVVAQIDPKKLKRKQSVNISLSG-CQPAPEGYSPTLQWQQQQVAQFSTVRQNVNKHRSHWKSQQLDSNVTMPKSEDEEGWKKFCLGEKLCADGAVGPATNESPGIDYVQIGFPPLLSIVSRMNQATVTSVLEYLSNWFGERDFTPELG------RWLYALLACLEKPLLPEAHSLIRQLARRCSEVRLLVDSKDDERVPALNLLICLVSRYFDQRDLADEPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N4X7-1", "uniprot_id": "A0A8M1N4X7_DANRE", "id": "A0A8M1N4X7-1", "name": "Gem-associated protein 2", "aln": "----------------MKSDAEELMPRLLPVDSCD-TEEYTLTEPPRNPQEYLRFVQREASLCPDVVVAQIDPKKLK-KQSVNVSITG-CLAAPEGFSPSFKWQQQQVSRFSEVRQSVNKHRQHWKAQFLDDNVVMPKTEDEDGWKRFCFGENVCLEIQLKEEDGVNPGLDYVKTGFPPFLSIVSKLSQSTVSAVLEYLINWFEERDFVPQLG------RWLYALLACLEKPLLPEAHSLIRQLARRCSAVRANLESKDDDRLSALNLMICIVARYFEQNDLADKE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVX0-1", "uniprot_id": "GEMI2_DROME", "id": "Q9VVX0-1", "name": "Gem-associated protein 2", "aln": "----------------MQHEPEDQTFQLQALEICEPDSSFDPQKPPESGEEYLMHMFYERKRCPAVVTKRSSKIRNNTGNTTLEMLDNPELPPFKCLLPTPEWRDEQVKSFQAARSQVLVLRKELANNNYDQSGEPPLTSDQEKWKEFCRNQ-------------------------QPLLSTLLHLTQNDLELLLEMLSKWLQDPNTTVDLLHDVWLARWLYATLVCLHLPLEPHVFSTLRYIARTCIHLRNQLKEDEVQRAAPYNLLLTLTVQVFAQNDFKDYI-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: :* .:: *: . : **.. :*** : * ** **. : . : : ::. : . .. : *: :*:::** *. .*..* *.. : *.. * :.*:: **.** .: *:** : ::.* : :** * :*: : : . :* **:** *.**. ** *...* :* :** * :* : ..: :* .. **:: :. : * *.*: * ", "identical_positions": 60, "similar_positions": 83, "identity": "20.91%" }, { "cls_id": "homologset.agr.RGD:620843", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60663-1", "uniprot_id": "LMX1B_HUMAN", "id": "O60663-1", "name": "LIM homeobox transcription factor 1-beta", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MDIATGPESLERCFPRGQTDCAKMLDGIKMEEHALRP------------GPATLG-------------------------------------VLLGSDCP------------HPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFA-AKCSGCMEKIAPTEFVMRAL-ECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRL--GQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYG-------SSDPFQQGL--TPPQMPGDH------MNPYGNDSIFHDIDSDTSLTSLSDCFLGSSD----------------VGSLQARVGNPIDRLYSMQSSYFAS-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V877-1", "uniprot_id": "G3V877_RAT", "id": "G3V877-1", "name": "LIM homeobox transcription factor 1-beta", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MDIATGPESLERCFPRGQTDCAKMLDGIKMEEHALRP------------GPATLG-------------------------------------VLLGSDCP------------HPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFA-AKCSGCMEKIAPTEFVMRAL-ECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQNKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRL--GQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYG-------SSDPFQQGL--TPPQMPGDH------MNPYGNDSIFHDIDSDTSLTSLSDCFLGSSD----------------VGSLQARVGNPIDRLYSMQSSYFAS-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88609-1", "uniprot_id": "LMX1B_MOUSE", "id": "O88609-1", "name": "LIM homeobox transcription factor 1-beta", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MDIATGPESLERCFPRGQTDCAKMLDGIKMEEHALRP------------GPATLG-------------------------------------VLLGSDCP------------HPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFA-AKCSGCMEKIAPTEFVMRAL-ECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRL--GQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYG-------SSDPFQQGL--TPPQMP-------------GNDSIFHDIDSDTSLTSLSDCFLGSSD----------------VGSLQARVGNPIDRLYSMQSSYFAS-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VTW5-1", "uniprot_id": "Q9VTW5_DROME", "id": "Q9VTW5-1", "name": "", "aln": "-MLEFYPMPTNLNPVGGSLYSLQQNHGGARFLDNPNPGSMTASSGNSLHLSNSNNNLPTSISGNNSPTATASLTGQHQQHQQQQHQQQQQHPHQQHQQHQQQHAASTTPVPINSCPTPTGHSPLSSSSSNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAAASAAAVAAPSPAGTSVATSQLGGAVAAAIAAAAAAAAAATTPTSTGPAATGSGNANGSGNGNGNGNGNGNGNGNGNGGGAATASAAAASKLSADCSGRTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCKMDYDRLFG-VKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCY-RHDLEKEMFLAAAAAQHCGFVGLDEEDLLRPRDGR--------------RGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGGSGGGSGS--GRGTGNSSATDDKDTNDKEDKCVKQELGGDSSGYLGGLDSTFASQPLNPNLPFSPDDYPANSNDSFCSSDLSLDGSNFDQLDDDADSLSLNNLELQSTSSSGNQHSHSHSNPHDMLANLNNSLINPIDKLYLMQNSYFSSEH---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTW3-1", "uniprot_id": "Q9VTW3_DROME", "id": "Q9VTW3-1", "name": "LIM homeobox transcription factor 1-beta", "aln": "MIDEHHPMQIGMFPMDIKCQQQQLGAG---------QLPQTGGLNQLLLLNGNERMLTTPTTAATSVVVAAGRSASTKAGVAHNDKMASVSRTVNGSCSNHNSSNSSSSSSTNSSSNMAINKQPMGMGPGTGTGMGTGTGHGPGPPNHTHCNRITLGECSLNGMDGFATPAAPPSASNTPQAPLGMASNSGMGMELG--------------------------------------------------------LAMASP------------QLSQCAHCCQPICDRYIMRVVENSFHEGCLKCTACSLHLVHSCYAREGKLYCRVDYERLYIRNHCLGCGLKIAADELVMRCH-ENVFHLKCFACVVCGALLKKGEQYVVKQGQLFCRFDYEKEVEMLQGYDFYGDELFPPKLDGR----------------------RGPKRPRTILNTQQRRAFKASFEVSPKPCRKVRENLAKDTGLSLRIVQVWFQNQRAKVKKIQKKAKQEPPSKGASDSQDSQESLDSSLATKIKDEAHSDSESQLESPYSTTSDG--------LTRMRCTIKDEQEQVPFNC------METNKENCNKNSEPILNTILGLSYATFQQLMG----------------PFAQTPMINPIDRLYSMQSSYFRPEELQSYGECGVKDSMDH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * . . *. . *. .. : * * : * **::*.* : .:** ** * * * :** *: ****: **::*: :* .* * . *:*** : *:** ** * .* *:**:::::::***:* :: * ::: . . : * ********.:***: *****: *.******** ** :****:*:***********:**: :: :*: . ... .: .* : . : :. : : * :.. .. .*. : . : : ****:** **.*** . ", "identical_positions": 110, "similar_positions": 90, "identity": "16.32%" }, { "cls_id": "homologset.agr.RGD:620844", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35430-1", "uniprot_id": "APBA1_RAT", "id": "O35430-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 1", "aln": "-----------------------------------------------------------------------------------------------------------------MNHLEG--------SAEVEVADEAPGGE-------------------------------------------------VNESVEADLEH-------------PEVEEEQQPSP---------------------------------------------------------------------------------------PPPAGHAPEDHRAHPAPPPP--------------------------------------------------------------------------------------------------------------PPPQE---------------------EEEE-RGECLARSASTES-------------GFHNHTDTAEG---------------------------------------------DVLAAARDGYEAERAQDADDES-----------------------------------------------------------------------------------------------------AYAVQYRPEAEEYTEQAEAEHAEAAQRRA---------------------------------------------------------------------------------------------------LPNH-----------------------------------------------------------------------LHFHSLEHEEAMN------------------------------------------------------------AAYSGYVYTHRLFHR------------AEDEPYAEPYADYGG-----------------LQEHVYEEIG-----------------DAPELEARDGLRLYERERD-------------------EAAAYR-QEALGARLHH--------------YDERSDGE----------------------------------------SDSPEKEAEFAPYPRMDSYEQEED-------------IDQIVAEVKQSMSSQSLDKAAEDMP-EAEQDLER---------------------------------------------------------------------------------APTPGGGHPDSPGLPAPAGQQQRVVGTPGGSEVGQRYSK--------------------------------------------------EKRDAISLAIKDIKEAIEEVKTR--------------------------------------TIRSPYTPDE---PKEPIWVMR------------------------QDISPTRDCDDQRPVD------------------------------GDSPSPGSSSPLGAESSITPLHP--------------------------------------------------------------------------------GDPTEAST--NKESRKSLASFPT-------------------------------------------------------------------------YVEVPGPCDPED---------LIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKTAQKLAKSRKKAPEGESQPMTEVDLFISTQRIKVLNADTQEPMMDHPLRTISYIADIGNIVVLMARRRMPRSN------SQENVEASHPSQDA------------KRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RUJ5-1", "uniprot_id": "APBA1_MOUSE", "id": "B2RUJ5-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 1", "aln": "-----------------------------------------------------------------------------------------------------------------MNHLEG--------SAEVEVADEAPGGE-------------------------------------------------VNESVEADLEH-------------PEVVEGQQPSPSP-------------------------------------------------------------------------------------PPPAGHEPEDHRGHPAPPPP--------------------------------------------------------------------------------------------------------------PPPQE---------------------EEEEERGECLARSASTES-------------GFHNHTDTAEG---------------------------------------------DVLAAARDGYEAERAQDADDES-----------------------------------------------------------------------------------------------------AYAVQYRPEAEEYTEQAEAEHVEAAQRRA---------------------------------------------------------------------------------------------------LPNH-----------------------------------------------------------------------LHFHSLEHEEAMN------------------------------------------------------------AAYSGYVYTHRLFHR------------AEDEPYAEPYADYGG-----------------LQEHVYEEIG-----------------DAPELEARDGLRLYERERD-------------------EAAAYR-QEALGARLHH--------------YDERSDGE----------------------------------------SDSPEKEAEFAPYPRMDSYEQEED-------------IDQIVAEVKQSMSSQSLDKAAEDMP-EAEQDLER---------------------------------------------------------------------------------APTPGGGHPDSPGLPAPAGQQQRVVGTPGGSEVGQRYSK--------------------------------------------------EKRDAISLAIKDIKEAIEEVKTR--------------------------------------TIRSPYTPDE---PKEPIWVMR------------------------QDISPTRDCDDQRPVD------------------------------GDSPSPGSSSPLGAESSSIPLHP--------------------------------------------------------------------------------GDPTEAST--NKESRKSLASFPT-------------------------------------------------------------------------YVEVPGPCDPED---------LIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKTAQKLAKSRKKAPEGESQPMTEVDLFISTQRIKVLNADTQEPMMDHPLRTISYIADIGNIVVLMARRRMPRSN------SQENVEASHPSQDG------------KRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02410-1", "uniprot_id": "APBA1_HUMAN", "id": "Q02410-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 1", "aln": "-----------------------------------------------------------------------------------------------------------------MNHLEG--------SAEVEVTDEAAGGE-------------------------------------------------VNESVEADLEH-------------PEVEEEQQQPP-----------------------------------------------------------------------------------------QQQHYVGRHQRGRALEDL--------------------------------------------------------------------------------------------------------------RAQLG---------------------QEEEERGECLARSASTES-------------GFHNHTDTAEG---------------------------------------------DVIAAARDGYDAERAQDPEDES-----------------------------------------------------------------------------------------------------AYAVQYRPEAEEYTEQAEAEHAEATHRRA---------------------------------------------------------------------------------------------------LPNH-----------------------------------------------------------------------LHFHSLEHEEAMN------------------------------------------------------------AAYSGYVYTHRLFHR------------GEDEPYSEPYADYGG-----------------LQEHVYEEIG-----------------DAPELDARDGLRLYEQERD-------------------EAAAYR-QEALGARLHH--------------YDERSDGE----------------------------------------SDSPEKEAEFAPYPRMDSYEQEED-------------IDQIVAEVKQSMSSQSLDKAAEDMP-EAEQDLER---------------------------------------------------------------------------------PPTPAGGRPDSPGLQAPAGQQ-RAVGPAGGGEAGQRYSK--------------------------------------------------EKRDAISLAIKDIKEAIEEVKTR--------------------------------------TIRSPYTPDE---PKEPIWVMR------------------------QDISPTRDCDDQRPMD------------------------------GDSPSPGSSSPLGAESSSTSLHP--------------------------------------------------------------------------------SDPVEAST--NKESRKSLASFPT-------------------------------------------------------------------------YVEVPGPCDPED---------LIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKMAQKLAKSRKKAPEGESQPMTEVDLFISTQRIKVLNADTQETMMDHPLRTISYIADIGNIVVLMARRRMPRSN------SQENVEASHPSQDG------------KRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7S5-1", "uniprot_id": "A0A8M1Q7S5_DANRE", "id": "A0A8M1Q7S5-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------MSHQEAPHGQELREAAEADLERRGPEGQQPPSSHRRRHNNGDGS-------------------------------SRSNRSRNHGTEN-------------NHHQSQHQGAPRY-------------------------------------------------------------------------------------RRCEGSNGGTNRTHAARRPEEEGDAEQQTI-----------------------------------QQPIPRPAVTRYRRQGDNEARLRAQQQRQRQRERQQRDAERAEQHRLEQQQQLLSPTQTMLPTREPEEAE---------------------EDEGDGSSALARSASTES-------------GFHNHTDRAEG---------------------------------------------DAVMVL----EAE----PEDEN-----------------------------------------------------------------------------------------------------TYGIPLRPEAEEYTESAESEQQHGGPAYL---------------------------------------------------------------------------------------------------QPQYPPQP-----------------------------------------------------------PPLPREPLPNAERPLEAETLN------------------------------------------------------------PNYSSYVYTQPMYHNPTEAGEAHEGGATEDEQYSEPYVDYT------------------LQEHVYEEIT-----------------DAPLSRAEGQTPQQQRPEFR----------------LFERDLYQQQEAVGSRLHH--------------YDERSDGE----------------------------------------SDSPEKEAEFAPYPRADSCEQDED-------------IDQIVAEVKESLSSQSLDRIAMGLNKDGDKEEDW---------------------------------------------------------------------------------PESESHGQLNDNNPLEPVSEGELPRSPSEDQAPVIRSSR--------------------------------------------------EKRDAISLAIKDIKEAIEEVKTR--------------------------------------TVRSPYTPDE---PKEPIWVMR------------------------QDLSPTAESDLQPSLG------------------------------ADSPGSGSTSPQGAESSSHQMMSQ-----------------------------------------------------------------------------EGSDSFESPSPAGKESRRSLASFPT-------------------------------------------------------------------------YVEVPGPCDPED---------LIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKTAQKLAKNKKKAPEGDAQPMTEVDLFISTQRIKVLNADSQETMMDHPLRTISYIADIGNIVVLMARRRMPRSD------SQENMEASDPAQDE------------KRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDLLNTQDMYNDDLIHFSKSENCKDVYIEKQKGEILGLVIVESGWGSILPTVIIANMMHGGPAEKSGRLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRIKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINSQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JE74-1", "uniprot_id": "X2JE74_DROME", "id": "X2JE74-1", "name": "", "aln": "--------------------------------------------------------------------MNSNSCSDSSNE---------------------SMVNPP-----HIQMNFG-----QQAQQQQSHQHQQQQQQQ--------ERYVWEMRTRS-----------------------------PNVTPASTVLN------------SPDLNGELSYVPLQGLSP---------------------------------------------------------------------------------SGGGVQGSGSYGSNAGRDS----------------------------------------------------------------------------------GSYYYQR-------------PQLHQIRLGRSPGS-----------------------QFETRDVLPQGLASP--------------GSPTDVGKADG----------------------------------------QCLRDGEIVVFDDIDTNWMNKASSGQR---------------------------------PGSNEDVLKVT----------------KMIGQLP------------------------------------IAEYEGSPRRFGSQPNTNTITMGGPRK-----------------------RP------------------------------------------------------------------------PGFPQRVSP------------------------------------TTSVANN----------------ATAAAKASVGNLIDLVDHEEE-------------------------------------RSG------------------TLREKTPTFDYLYEFSETRKVLEEFFKANPEDEKRYTDYTTESG----------------DDVASSQPQE-----------------YPATPMEQAYIGQRLARIPK-----DELYMVHR----SPTKKPPSDQNPSTAYQEHN-------DIELYIDSNSRSSGD-------LADTELEANLRRHS----------------RNFTLSPETTDYDSNCGDLDSLSNDIN-----CPTDFGKLYTS-MPVLEDGLSSGHASDTENNVSVVCDKQQSSQSQP---------VHEHNGNG--------ERLENDYNVMSAS----LATLTTDAS------QSALISDFASLPMP-------PAPPPSSPPQIEIADASES--MTMVPDADNPLDSHYGA----------VYAAALGGTHTEKSAGSGLGVTPVTAGGSLPS--------QAASEIQEAMKEIRSALQRAKTQ----------------------------------PEKLKFCDEVLPTD---PDSPVWVPR------------KGTTISTAQGAAADEEPDTDLETDRLLGQQRHDEQDFFADQSLADNN-ANEGTDIASNGHLNGTSDNNNPNPMNNSKPQTYSTATIR--QGIGTSLTP---NSPDICQIVG-------------------------------------------TTDISISSPEKLQFTKSPTGSIKSLKDSAN-------------------------------------------------------------------SDKKAKSRNKEGLLEPK---------VLIEGVLFRARYLGSTQLVCEGQPTKSTRMMQAEEAVSRIK---------ALAPEGESQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVPNSVVDPSITSPLGDVPTPGIGEEESPPKEPLSKHNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIENESLAKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGMSLVGLPLSTCQSYIRNAKNQTAVKFTVVPCPPVVEVKILRPKALFQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHDTIVKLLSSSVGEILMKTMPTSMFRLLTGQETPIYI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2S5-1", "uniprot_id": "Q9W2S5_DROME", "id": "Q9W2S5-1", "name": "", "aln": "MVSTTLTTLAAGQTTSSSNHHHHHHHSHQQQQQQQQQDQSQQQPHQQLPYQQRGYYALNGSLELDCDTSNTNSSSSSNNIGYQQHQQQQQQQQQPPLILSQALLSPSPPLNDQISLLFPKCRPKQQQQQQQQQQQQQQQQQQQLQPAQQHQQHVHPTDVNSSCNSNRSSSPTTAGAVGEPLASVSVSPPPPKATPTSSTPSYYKSVNIITQSPPPHSASSHSSESLSSVTPRISTNPFLCAPLTPPTPPHHHHHHHHQQQHQQKQQQPKQQHQTQQQEQQEEDTTGESVVEHSRSGAAGEVLEYPASFYYHTVGDSRRGPGSYTEMPRKRSSALPASNRQQQLHNGNGSQNPFIKENYWEAPPTRASLLLHSPTEYSEEPQQQQQIQQQQQQQQQQQQQQQQQQQQHLHASARRAYHQQREQVYGINQRPQQQQQQNILRVGRSPVNRSFPQQHQQQQQQQQQQQQQQQQQQQPHQQIPTARSNPCADGLTPLASHYLYGSKSSLDQHPGDWEPREQRKLRLREEREREREREREREREREREHLLLEQQQQLQLQEVQVARDNHLSHLAGQQQQQQQRKRHVYGEERERERDRERDMDRDHRLVNGNADPNESWQHLRVTTETLAEEGGKHGKPADKAQHQMHNTNQSQNSDVNVYREHQLDAWKLERSYTLAVESRHGIIEYEGSPRRIGVTTTSNLGATGAAAASAAADESEPPAAAEGAAAATATSQPQQQVPMATVPPLSSTATSLQKTAARAALAALAQSHPHSSHNILSTLLPHSPNPVNPGQMHAAQQSIQNYPVRPGFPQRIISPPSRDPRSSSPPLQQQQYQQQQQQQLQHQQQHFASLMSSHSNNNSNTNKQPLSSDNNAEDTSNDVSEIGTISDLTTPEAVGLSIGIAAGEMASRASTPPQTAQAPPTAVAGSTANGTGSGNGTATGNATAAGSGLGPLSLHTKSSTFDYLYEFSETRKVLEEFFKCPSTDEQPIMENGSDVDSIDIQYEFHSNFERDEEDLAEEEEAEDDEEVDDDADEENDEAEDEDEPLEQDRDQNYRAQAPPQSGHIDSERLVYSGYGQQPQLQAQLTAQPMSGARRHYSGSPLMRDFDFFLDSTSRSSGERDADQDGLNHNQLLSTSSGHGGGVGVSGGLGVGPGGGHNYRYSPETTDYDSNCGDLDSLSGEMNGGVSTSCSNYAKFYASAMPVLEDGLSSGHTSDTENNNNNQKNLQQSTVNQGGQCPTSLSGSTSIGGSGGISMLMDMKRISTNHSLNSMNNQTTTASTTTDSNGGVGGVGHHLVATLVASPNNEQAKSQCQTQLQSHPPKTLSLDQSPSNHSKVFKNIDPELDSLYSIGVFHRPDTVQMTPPPPAPAPHRKPNNNGCSSGVVNTNGSLAGGSNDVDLLQPSSKHTPLAAAISSTLQRSSPTSTITGNGIGNGSGKTRSAGSNCSSSANGGMPPPIPERTNLVSAVQRSPSPGPNSPVWLSRHLDGGAGKDLLESGSDNHSKNHSADEEDVDTDLETDRLLGHQRLDDQGYYDENKSWDRKPRSLLSKISPKQQIPSTKTRNGYNALLSSTPELPPPIPPKGQSGLGLGLTLGAGNGGKLLDLVGGMVQRSLSRSSSEHSEKSLSKMPISGGDLCAGGVDVVASTVAATSATVVASTPALGSPGNGGGSERSAAEMANPGGAVKLSEQEIGTINGGSVMPLGSGSGTGSGAGSGAGSGTGTNAAVVANSNANNNVGGGGGGGNNSSGSGAGSNSNSGEKKVKKSKSKEGGAVLIEGVLFRAKYLGSTQLVCEGQPTKSTRMMQAEEAVSRIK---------ALAPDGDVQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVP---------QDIDDAPKP----------------NRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIEDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . . : : : . . . : . :. . :. * . . * : . . : . .... . :: *: * . : * : . ::: : : : . * * . : . : * .**.*: ***. : ** . : : . :. :::.:** . . : : . : . . . . . : . * .:::. .. .. . *..*:*: * : . : : : :. . .. . .. . . . * :* . .. . * . : **:*::* *.*******:.: *:*..*****:******* **:*: ** *********::* ***:* :* ****.***********::********: . :.. * :* *********::**:*********.*** ***:****: . : : :*.::**:*:::.*:* *:*.* *:* : * ******:*********:****:***:* .*.* :.*:******:::*** ***********: *:. ***: :*:.:* *.**. * * **. :*********:****:********************.*****.**:.**::*:.:**** *****::*:****.** *:**", "identical_positions": 260, "similar_positions": 203, "identity": "11.97%" }, { "cls_id": "homologset.agr.RGD:620845", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35431-1", "uniprot_id": "APBA2_RAT", "id": "O35431-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAHRKRQSTASSMLDH--------------------------------------------------RARPGP----------------IPHDQEPENE-------------------------------------------------------------------------------------------DTELPLESYVPTG-LELGT--------------------------------------------------------------------------------------------------------------------------------------------LRPDSPTPEEQE-----------------CHNHSPDG----------------------------------------------------DSSSDYVNNTSEEE-------------------------------------------------------------DYDEGLP-------------------------------------EEEEGVTYYIRYCPEDDSYLEG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDCNGEEYL-------------------------------------------------------------AHG---AHPVDTDECQEAVEDWT----DSVGPHTHSHGAENS-------------------------------------------------QEYPD---SHLPIP----EDDPTVLEVH-------DQEEDGHYCPSKESYQ--------DYYPPETNGNTGG-------------ASPYRMRR---------------------GDG--DLEEQEEDIDQIVAEIK-----------------MSLSMTSITSASEASP-------------------------------------------------------------------------------------------------EHMPELDPG----DSTEA--------------------------------CSPSDTGR-GPSRQEA---------------------RPKSLNLPPEVKHSGDPQRGLKT-------------------------------------------KTRTP---EERPKWPQ---------------------------EQVCNGLEQPRKQ--QRSD---------------------------LNGPTDNNNIPE-TKKVASFPSFVAVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPCEPED---------LIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANS-EGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPR---------SASQDCIETTPGAQEG---------KKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98084-1", "uniprot_id": "APBA2_MOUSE", "id": "P98084-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAHRKRQSTASSMLDH--------------------------------------------------RARPGP----------------IPHDQEPESE-------------------------------------------------------------------------------------------DTELPLESYVPTG-LELGT--------------------------------------------------------------------------------------------------------------------------------------------LRPESPTPEEQE-----------------CHNHSPDG----------------------------------------------------DSSSDYVNNTSEEE-------------------------------------------------------------DYDEGLP-------------------------------------EEEEGVTYYIRYCPEDDSYLEG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDCNGEEYI-------------------------------------------------------------AHG---AHPVDTDECQEAVEDWT----DSVGPHTHSHGAENS-------------------------------------------------QEYPD---GHLPIP----EDDPTVLEVH-------DQEEDGHYCSSKESYQ--------DYYPPETNGNTGG-------------ASPYRMRR---------------------GDG--DLEEQEEDIDQIVAEIK-----------------MSLSMTSITSASEASP-------------------------------------------------------------------------------------------------EHMPELDPG----DSTEA--------------------------------CPPSDTGH-GPGRQEA---------------------RPKSLNLPPEVKHPGDLQRGLKT-------------------------------------------KTRTP---EERPKWPQ---------------------------EQVCNGLEQPRKQ--QRSD---------------------------LNGPTDNNNIPE-TKKVASFPSFVAVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPCEAED---------LIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANS-EGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPR---------SASQDCIETTPGAQEG---------KKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99767-1", "uniprot_id": "APBA2_HUMAN", "id": "Q99767-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAHRKLESVGSGMLDH--------------------------------------------------RVRPGP----------------VPHSQEPESE-------------------------------------------------------------------------------------------DMELPLEGYVPEG-LELAA--------------------------------------------------------------------------------------------------------------------------------------------LRPESPAPEEQE-----------------CHNHSPDG----------------------------------------------------DSSSDYVNNTSEEE-------------------------------------------------------------DYDEGLP-------------------------------------EEEEGITYYIRYCPEDDSYLEG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDCNGEEYL-------------------------------------------------------------AHS---AHPVDTDECQEAVEEWT----DSAGPHPHGHEAEGS-------------------------------------------------QDYPD---GQLPIP----EDEPSVLEAH-------DQEEDGHYCASKEGYQ--------DYYPEEANGNTG--------------ASPYRLRR---------------------GDG--DLEDQEEDIDQIVAEIK-----------------MSLSMTSITSASEASP-------------------------------------------------------------------------------------------------EHGPEPGPE----DSVEA--------------------------------CPPIKASC-SPSRHEA---------------------RPKSLNLLPEAKHPGDPQRGFKP-------------------------------------------KTRTP---EERLKWPH---------------------------EQVCNGLEQPRKQ--QRSD---------------------------LNGPVDNNNIPE-TKKVASFPSFVAVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPCEPED---------LIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANS-EGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPR---------SASQDCIETTPGAQEG---------KKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BG86-1", "uniprot_id": "A0A8M2BG86_DANRE", "id": "A0A8M2BG86-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAQRKRPGINSGMATEPH--------------------------------------------APAPRSCPAP----------------YPDPEHPEEEYEEH--------------------------------------------------------------------------------------HDPEVTQHSYHNQEEADLTD--------------------------------------------------------------------------------------------------------------------------------------------SRPTTPTTPDHAHR------------DYHSHPDSLDG----------------------------------------------------DSSSDYVNNTSDEEE-----------------------------------------------------------DDFDEGLP-------------------------------------EEDEGVTYYIRYCPEDDSYLEG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDCNDPEYV-------------------------------------------------------------HPDGRMEPPPDTDECQEAVEEWVEGEDDAQGDEDDDDEEDDDDDDDGEVRCEVLEQDSDQQLYDGRPE---------------PVLDHHHHQHYTDPHQEQLPPP----IEDQEVKDVEGSERYCPDQEEEPQVGRDREGYAG-------DYYATEDNGNSVR-------------ASPYRGHK---------------------GTEGETGEEAEEDIDQIVAEIK-----------------MSMSMGSLSSGTDQSPE------------------------------------------------------------------------------------------------ELAPDPAPSGYQPETRSK--------------------------------PEPAPAPYPQPHRHDG---------------------RPKSLNIPPARHNP-ELQRNFKV-------------------------------------------RPHTP---EDRQRWTQD-----------------------QVREQMSNSAEQPRKQ--QRSD---------------------------LNGPLENNNVTEPTKKTASFPSFVDVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPCEPED---------LIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRVQKAAKIKKKAQSPEGDAQTLTEVDLFISTQRIKVLNADTQETMMDNALRTISYIADIGNIVVLMARRRMPR---------TASQDCIETTPGAPEA---------KKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDIINTQEMYNDDLIHFSNSDNCKELQLEKQKGEILGIVIVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINNTSLVGLPLATCQGIIKGLKNQVQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPMYI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JE74-1", "uniprot_id": "X2JE74_DROME", "id": "X2JE74-1", "name": "", "aln": "--------------------------------------------------------------------MNSNSCSDSSNE---------------------SMVNPP-----HIQMNFG-----QQAQQQQSHQHQQQQQQQ--------ERYVWEMRTRS-----------------------------PNVTPASTVLN------------SPDLNGELSYVPLQGLSP---------------------------------------------------------------------------------SGGGVQGSGSYGSNAGRDS----------------------------------------------------------------------------------GSYYYQR-------------PQLHQIRLGRSPGS-----------------------QFETRDVLPQGLASP--------------GSPTDVGKADG----------------------------------------QCLRDGEIVVFDDIDTNWMNKASSGQR---------------------------------PGSNEDVLKVT----------------KMIGQLP------------------------------------IAEYEGSPRRFGSQPNTNTITMGGPRK-----------------------RP------------------------------------------------------------------------PGFPQRVSP------------------------------------TTSVANN----------------ATAAAKASVGNLIDLVDHEEE-------------------------------------RSG------------------TLREKTPTFDYLYEFSETRKVLEEFFKANPEDEKRYTDYTTESG----------------DDVASSQPQE-----------------YPATPMEQAYIGQRLARIPK-----DELYMVHR----SPTKKPPSDQNPSTAYQEHN-------DIELYIDSNSRSSGD-------LADTELEANLRRHS----------------RNFTLSPETTDYDSNCGDLDSLSNDIN-----CPTDFGKLYTS-MPVLEDGLSSGHASDTENNVSVVCDKQQSSQSQP---------VHEHNGNG--------ERLENDYNVMSAS----LATLTTDAS------QSALISDFASLPMP-------PAPPPSSPPQIEIADASES--MTMVPDADNPLDSHYGA----------VYAAALGGTHTEKSAGSGLGVTPVTAGGSLPS--------QAASEIQEAMKEIRSALQRAKTQ----------------------------------PEKLKFCDEVLPTD---PDSPVWVPR------------KGTTISTAQGAAADEEPDTDLETDRLLGQQRHDEQDFFADQSLADNN-ANEGTDIASNGHLNGTSDNNNPNPMNNSKPQTYSTATIR--QGIGTSLTP---NSPDICQIVG-------------------------------------------TTDISISSPEKLQFTKSPTGSIKSLKDSAN-------------------------------------------------------------------SDKKAKSRNKEGLLEPK---------VLIEGVLFRARYLGSTQLVCEGQPTKSTRMMQAEEAVSRIK-----------ALAPEGESQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVPNSVVDPSITSPLGDVPTPGIGEEESPPKEPLSKHNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIENESLAKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGMSLVGLPLSTCQSYIRNAKNQTAVKFTVVPCPPVVEVKILRPKALFQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHDTIVKLLSSSVGEILMKTMPTSMFRLLTGQETPIYI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2S5-1", "uniprot_id": "Q9W2S5_DROME", "id": "Q9W2S5-1", "name": "", "aln": "MVSTTLTTLAAGQTTSSSNHHHHHHHSHQQQQQQQQQDQSQQQPHQQLPYQQRGYYALNGSLELDCDTSNTNSSSSSNNIGYQQHQQQQQQQQQPPLILSQALLSPSPPLNDQISLLFPKCRPKQQQQQQQQQQQQQQQQQQQLQPAQQHQQHVHPTDVNSSCNSNRSSSPTTAGAVGEPLASVSVSPPPPKATPTSSTPSYYKSVNIITQSPPPHSASSHSSESLSSVTPRISTNPFLCAPLTPPTPPHHHHHHHHQQQHQQKQQQPKQQHQTQQQEQQEEDTTGESVVEHSRSGAAGEVLEYPASFYYHTVGDSRRGPGSYTEMPRKRSSALPASNRQQQLHNGNGSQNPFIKENYWEAPPTRASLLLHSPTEYSEEPQQQQQIQQQQQQQQQQQQQQQQQQQQHLHASARRAYHQQREQVYGINQRPQQQQQQNILRVGRSPVNRSFPQQHQQQQQQQQQQQQQQQQQQQPHQQIPTARSNPCADGLTPLASHYLYGSKSSLDQHPGDWEPREQRKLRLREEREREREREREREREREREHLLLEQQQQLQLQEVQVARDNHLSHLAGQQQQQQQRKRHVYGEERERERDRERDMDRDHRLVNGNADPNESWQHLRVTTETLAEEGGKHGKPADKAQHQMHNTNQSQNSDVNVYREHQLDAWKLERSYTLAVESRHGIIEYEGSPRRIGVTTTSNLGATGAAAASAAADESEPPAAAEGAAAATATSQPQQQVPMATVPPLSSTATSLQKTAARAALAALAQSHPHSSHNILSTLLPHSPNPVNPGQMHAAQQSIQNYPVRPGFPQRIISPPSRDPRSSSPPLQQQQYQQQQQQQLQHQQQHFASLMSSHSNNNSNTNKQPLSSDNNAEDTSNDVSEIGTISDLTTPEAVGLSIGIAAGEMASRASTPPQTAQAPPTAVAGSTANGTGSGNGTATGNATAAGSGLGPLSLHTKSSTFDYLYEFSETRKVLEEFFKCPSTDEQPIMENGSDVDSIDIQYEFHSNFERDEEDLAEEEEAEDDEEVDDDADEENDEAEDEDEPLEQDRDQNYRAQAPPQSGHIDSERLVYSGYGQQPQLQAQLTAQPMSGARRHYSGSPLMRDFDFFLDSTSRSSGERDADQDGLNHNQLLSTSSGHGGGVGVSGGLGVGPGGGHNYRYSPETTDYDSNCGDLDSLSGEMNGGVSTSCSNYAKFYASAMPVLEDGLSSGHTSDTENNNNNQKNLQQSTVNQGGQCPTSLSGSTSIGGSGGISMLMDMKRISTNHSLNSMNNQTTTASTTTDSNGGVGGVGHHLVATLVASPNNEQAKSQCQTQLQSHPPKTLSLDQSPSNHSKVFKNIDPELDSLYSIGVFHRPDTVQMTPPPPAPAPHRKPNNNGCSSGVVNTNGSLAGGSNDVDLLQPSSKHTPLAAAISSTLQRSSPTSTITGNGIGNGSGKTRSAGSNCSSSANGGMPPPIPERTNLVSAVQRSPSPGPNSPVWLSRHLDGGAGKDLLESGSDNHSKNHSADEEDVDTDLETDRLLGHQRLDDQGYYDENKSWDRKPRSLLSKISPKQQIPSTKTRNGYNALLSSTPELPPPIPPKGQSGLGLGLTLGAGNGGKLLDLVGGMVQRSLSRSSSEHSEKSLSKMPISGGDLCAGGVDVVASTVAATSATVVASTPALGSPGNGGGSERSAAEMANPGGAVKLSEQEIGTINGGSVMPLGSGSGTGSGAGSGAGSGTGTNAAVVANSNANNNVGGGGGGGNNSSGSGAGSNSNSGEKKVKKSKSKEGGAVLIEGVLFRAKYLGSTQLVCEGQPTKSTRMMQAEEAVSRIK-----------ALAPDGDVQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVP---------QDIDDAPKP----------------NRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIEDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: . . . * . *. . . .* : * . * * . : .. : . : * ** . : . : * * * : .* ::.:*:: . . * : * . * :. : : . . .: : : . :. *:*.: ::: *.: .::*. .. . * : : . :. * ** : : * *: .. * * ** * : .. .*. .. .. . * : : **:*::* *.*******:.* :*:*. *****:*****:* * : :*: *. *********::* ***:* :* ***:************::********: * . :: *********::**:*********.*** ***:****: . : : :*.:::*:**::.*:* *::.: **: : * ******:*:*******:****::**:*..*.***.*:*.****:::**. *******:*** *:. ***. **:.:*.*.**. * * **. :*********:****:********************.*****..*:.**: *:.***** *****::*********.*:**", "identical_positions": 263, "similar_positions": 179, "identity": "12.09%" }, { "cls_id": "homologset.agr.RGD:620846", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70248-1", "uniprot_id": "APBA3_RAT", "id": "O70248-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFLPEPQH--------------------------------------PPG-------PPTMDLEE-------------------------------PKGPEVPSEDHPSNT-----------QWALGPRG--PDTLS-----------EMELDTSSVR------------------------------ALVQQLEALPS-------------------------------------------------------DLGGQFPDGAP--------------------------------------------------CPLHIATGQGLATQ--ENLDAGGLLSAEAGG-------------------------------------------------------------------DNLLGLLRCEAS--------------------LPAQSVPP-------DPAQAAPRLLQPPEDPGGD----PGWMEGT--------------EPADNRSSSSSPELWLETAPL---------VTHRDPPVGTQSQETLASCPAVSEVPGPCGQEE-----------------------------------------------------------------------------------------------------LMDGVLFGAKYLGSTQLLSERNPPPSTRMGQAQEAMDRVK--APEGETQPMTEVDIFISTKRVKVLAADSQDALMDHALQTISYIADIGPVLVLMARRRLAKRTTSQD-RQRQLYKMLCHVFHSEDAQLIAQAIGQAFSIAYSQFLQENRIDPS----QVGMQPSASASHPHNGDLDHFCNSQNCREVCIQKRPGEGLGVALVESGWGSLLPTAVIANLLHGGPAERCGALSIGDRVTAINGTSLVGLSLAACQAAVREVRRHSSVTLSIIHCPPVTTAVIHRPHVREQLGFCVENGIICSLLRGSAAERGGVRVGHRIIEVNGQSVVAMPHARIIQLLTETR-EIHIKTMPAATYRLLTGQEQPVYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88888-1", "uniprot_id": "APBA3_MOUSE", "id": "O88888-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFLPGPQH--------------------------------------PPG-------PPTMDLEE-------------------------------PKGPEVPSENHPSNT-----------QSALGPGG--PVTLS-----------EMELDTSSVQ------------------------------ELVQQLEALPS-------------------------------------------------------DLGGPFPDGAP--------------------------------------------------CPLHIATGQGLATQ--ENPDAGGLLSAEAGG-------------------------------------------------------------------DDLLGLLRDEAS--------------------SPAQSVPQ-------DPAQTAPRLLQPPEDPDGD----PGWMEGAS------------AEPADSRSSSSSPEPWLETAPL---------VTQQEPPVGTQSRETLASCPAVTEVPGPCGPEE-----------------------------------------------------------------------------------------------------LMDGVIFGAKYLGSTQLLSERSPAPSTRMGQAQEAMDRVK--APEGETQPMVEVDIFISTKRVKVLAADSQDALMDHALQTISYIADIGPVLVLMARRRLARRTTPQD-RQRRLYKMLCHVFHSEDAQLIAQAIGQAFSIAYSQFLQENRIDPS----QVGTQPSTAASHPHNGDLDHFCNSQNCREVCIQKRPGEGLGVALVESGWGSLLPTAVIANLLHGGPAERCGALSIGDRVTAINGTSLVGLSLAACQAAVREVRRLSSVTLSIIHCPPVTTAVIRRPHVREQLGFCVEDGIICSLLRGGAAERGGVRVGHRIIEVNGQSVVAMPHARIIQLLTETR-EIHIKTMPAATYRLLTGQEQPVYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96018-1", "uniprot_id": "APBA3_HUMAN", "id": "O96018-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFPTISRS--------------------------------------PSG-------PPAMDLEG-------------------------------PRDILVPSEDLTPDS-----------QWDPMPGG--PGSLS-----------RMELDESSLQ------------------------------ELVQQFEALPG-------------------------------------------------------DLVGPSPGGAP--------------------------------------------------CPLHIATGHGLASQ--EIADAHGLLSAEAGR-------------------------------------------------------------------DDLLGLLHCEEC--------------------PPSQTGPE-------EPLEPAPRLLQPPEDPDEDSDS-PEWVEGAS------------AEQEGSRSSSSSPEPWLETVPL---------VTPEEPPAGAQSPETLASYPAPQEVPGPCDHED-----------------------------------------------------------------------------------------------------LLDGVIFGARYLGSTQLVSERNPPTSTRMAQAREAMDRVK--APDGETQPMTEVDLFVSTKRIKVLTADSQEAMMDHALHTISYTADIGCVLVLMARRRLARRPAPQD-HGRRLYKMLCHVFYAEDAQLIAQAIGQAFAAAYSQFLRESGIDPS----QVGVHPSPGACHLHNGDLDHFSNSDNCREVHLEKRRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAACQAAVRETKSQTSVTLSIVHCPPVTTAIIHRPHAREQLGFCVEDGIICSLLRGGIAERGGIRVGHRIIEINGQSVVATPHARIIELLTEAYGEVHIKTMPAATYRLLTGQEQPVYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2S5-1", "uniprot_id": "Q9W2S5_DROME", "id": "Q9W2S5-1", "name": "", "aln": "MVSTTLTTLAAGQTTSSSNHHHHHHHSHQQQQQQQQQDQSQQQPHQQLPYQQRGYYALNGSLELDCDTSNTNSSSSSNNIGYQQHQQQQQQQQQPPLILSQALLSPSPPLNDQISLLFPKCRPKQQQQQQQQQQQQQQQQQQQLQPAQQHQQHVHPTDVNSSCNSNRSSSPTTAGAVGEPLASVSVSPPPPKATPTSSTPSYYKSVNIITQSPPPHSASSHSSESLSSVTPRISTNPFLCAPLTPPTPPHHHHHHHHQQQHQQKQQQPKQQHQTQQQEQQEEDTTGESVVEHSRSGAAGEVLEYPASFYYHTVGDSRRGPGSYTEMPRKRSSALPASNRQQQLHNGNGSQNPFIKENYWEAPPTRASLLLHSPTEYSEEPQQQQQIQQQQQQQQQQQQQQQQQQQQHLHASARRAYHQQREQVYGINQRPQQQQQQNILRVGRSPVNRSFPQQHQQQQQQQQQQQQQQQQQQQPHQQIPTARSNPCADGLTPLASHYLYGSKSSLDQHPGDWEPREQRKLRLREEREREREREREREREREREHLLLEQQQQLQLQEVQVARDNHLSHLAGQQQQQQQRKRHVYGEERERERDRERDMDRDHRLVNGNADPNESWQHLRVTTETLAEEGGKHGKPADKAQHQMHNTNQSQNSDVNVYREHQLDAWKLERSYTLAVESRHGIIEYEGSPRRIGVTTTSNLGATGAAAASAAADESEPPAAAEGAAAATATSQPQQQVPMATVPPLSSTATSLQKTAARAALAALAQSHPHSSHNILSTLLPHSPNPVNPGQMHAAQQSIQNYPVRPGFPQRIISPPSRDPRSSSPPLQQQQYQQQQQQQLQHQQQHFASLMSSHSNNNSNTNKQPLSSDNNAEDTSNDVSEIGTISDLTTPEAVGLSIGIAAGEMASRASTPPQTAQAPPTAVAGSTANGTGSGNGTATGNATAAGSGLGPLSLHTKSSTFDYLYEFSETRKVLEEFFKCPSTDEQPIMENGSDVDSIDIQYEFHSNFERDEEDLAEEEEAEDDEEVDDDADEENDEAEDEDEPLEQDRDQNYRAQAPPQSGHIDSERLVYSGYGQQPQLQAQLTAQPMSGARRHYSGSPLMRDFDFFLDSTSRSSGERDADQDGLNHNQLLSTSSGHGGGVGVSGGLGVGPGGGHNYRYSPETTDYDSNCGDLDSLSGEMNGGVSTSCSNYAKFYASAMPVLEDGLSSGHTSDTENNNNNQKNLQQSTVNQGGQCPTSLSGSTSIGGSGGISMLMDMKRISTNHSLNSMNNQTTTASTTTDSNGGVGGVGHHLVATLVASPNNEQAKSQCQTQLQSHPPKTLSLDQSPSNHSKVFKNIDPELDSLYSIGVFHRPDTVQMTPPPPAPAPHRKPNNNGCSSGVVNTNGSLAGGSNDVDLLQPSSKHTPLAAAISSTLQRSSPTSTITGNGIGNGSGKTRSAGSNCSSSANGGMPPPIPERTNLVSAVQRSPSPGPNSPVWLSRHLDGGAGKDLLESGSDNHSKNHSADEEDVDTDLETDRLLGHQRLDDQGYYDENKSWDRKPRSLLSKISPKQQIPSTKTRNGYNALLSSTPELPPPIPPKGQSGLGLGLTLGAGNGGKLLDLVGGMVQRSLSRSSSEHSEKSLSKMPISGGDLCAGGVDVVASTVAATSATVVASTPALGSPGNGGGSERSAAEMANPGGAVKLSEQEIGTINGGSVMPLGSGSGTGSGAGSGAGSGTGTNAAVVANSNANNNVGGGGGGGNNSSGSGAGSNSNSGEKKVKKSKSKEGGAVLIEGVLFRAKYLGSTQLVCEGQPTKSTRMMQAEEAVSRIKALAPDGDVQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVPQDIDDAPKPNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIEDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* . * * * : * : * *.. ..:: * * * :** * :* . : ** : * *. :: * ** .* **:*:.. : .* . *:.*. * *** : : * * * :. .:. * ** * : *: : .****. .* *.. *: * ....: * .:** ** . . . * *::**:* *:*******:.* .*. **** **.**:.*:* **:*:.** .***:*:**::: ** :* :: :*****:**** **** ::*******:. : : : .: **:**** :::**:***:***** ** :**: . *: ::. : : . ...:*: *.:.: :** : * ** ***.:*******:***.*****: .*.* *.* *.***:: **** *****.*::**: :::.: : *.:::: *.**. . *:**..: ****.*::*:*******. *****:********:*.***** ** :*::**: : *: :****:: :*******:*:*:", "identical_positions": 236, "similar_positions": 172, "identity": "11.03%" }, { "cls_id": "homologset.agr.RGD:620847", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "C0H5Y5-1", "uniprot_id": "C0H5Y5_RAT", "id": "C0H5Y5-1", "name": "CASP8 and FADD-like apoptosis regulator", "aln": "MALSTVSAEVIHQVEESLDEDEKEMMLFLCRDVTENLAPPNVR-DLLDCLSERGQLS------FAALAELLYRVRRFDLLKRILKTDKAAVEDHLCRSPHLVSDYRVLLMEIGENLNQSDVSSLIFLTKDYTGRGKVAKDKSFLDLVIELEKLNLIGSDQLNLLEKCLKSIHRIDLKTKIQKYTQSSQEAR-SNMNALQASLPKLSIKEHLYNSRLQNGRSKEPRFVEHHGIQRKPVKTSIQESGIFLPPHIHEESYRMQSKPLGICLIIDCIGNDTEYLRETFTSLGYRVQPFLFPSSHEITQIVRRFSNMTQHQDYDSFVCVLVSRGGSQSMMGVDQVYSGFSLENVKDMFKGDMCPSLRGKPKLFFIQNYEAL-------EDNS-LEVDGPAIKNVNSRHLHPRHCTTHPDADIFWSLCTADVSRLEQPSSSLSVYLQKLSQLLEQGRKR--SLVDLHVELMDKVYAWNSNVPSKEKYYLSLQHTLRKKLILSHT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35732-1", "uniprot_id": "CFLAR_MOUSE", "id": "O35732-1", "name": "CASP8 and FADD-like apoptosis regulator", "aln": "MAQSPVSAEVIHQVEECLDEDEKEMMLFLCRDVTENLAAPNVR-DLLDSLSERGQLS------FATLAELLYRVRRFDLLKRILKTDKATVEDHLRRNPHLVSDYRVLLMEIGESLDQNDVSSLVFLTRDYTGRGKIAKDKSFLDLVIELEKLNLIASDQLNLLEKCLKNIHRIDLNTKIQKYTQSSQGAR-SNMNTLQASLPKLSIK---YNSRLQNGRSKEPRFVEYRDSQRTLVKTSIQESGAFLPPHIREETYRMQSKPLGICLIIDCIGNDTKYLQETFTSLGYHIQLFLFPKSHDITQIVRRYASMAQHQDYDSFACVLVSLGGSQSMMGRDQVHSGFSLDHVKNMFTGDTCPSLRGKPKLFFIQNYESLGS---QLEDSS-LEVDGPSIKNVDSKPLQPRHCTTHPEADIFWSLCTADVSHLEKPSSSSSVYLQKLSQQLKQGRRR--PLVDLHVELMDKVYAWNSGVSSKEKYSLSLQHTLRKKLILAPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15519-1", "uniprot_id": "CFLAR_HUMAN", "id": "O15519-1", "name": "CASP8 and FADD-like apoptosis regulator", "aln": "-----MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVR-DLLDILRERGKLS------VGDLAELLYRVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVLQAAIQK-SLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEG---QLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLRQERKR--PLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P2J9-1", "uniprot_id": "A0A8M1P2J9_DANRE", "id": "A0A8M1P2J9-1", "name": "", "aln": "--MADGFSTLVNKVTASLSSDESKILLYLCTDLFNNSCVEELRGDLLAFAQQNPNQAGQPHSGNALLMELMFQMKRYDLLRKVFGTNKQQVEGILRKE-RVISDYRVLMADVSENLDKEDLQSLIFLLSSILPKERSTRATSFLDVVVELEKLNEVSCEKLDFLEKCLKNIRRNDLVKKIQAYRNRGQNMPCAAPNTFKFTPMQ------------CQPFEKQVRQSQCFNHEFNKLKLSVPETGIHYQQAIT-EEYQMNPEQRGLCVIIDCVGYDGEMLKHTFECLGFKVVFHSLLGLKETQKVLEDLSLNRILQRVRCFVCCLISRGTNTHLLATDSNRLGINLKDLKQLFNATKCP------KIFFTQLYRITEAPVMPSMDDEYLETDAPASRQCSNTG------SVPMPADVLWSVCTAEVKLLEE-SGHQSVYLNALNNALLKGHERNVPILDVMKEVQRNVLSHDS-----DNYQLQQSHTLQKKLYL---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::::* .*. **.:::*:** *: : ::* *** :. : : . * **:::::*:***:::: :: ** * :. :::******: ::.*.*::.*:.**:** . : : :: .****:*:****** :. ::*::******.*:* ** .*** * : * : *.:: : : : .*: * : . : :* *: *: . * * *:*:.: *:*:****:* : : *:.** .**:.: . : ::: : : .*.* *:* * . : . *. *: *..:: :* . ** *:** * * *.. **.*.*: :: . :. **.:**:***::. **: . *:**: *.: * : :.* .::*: *: : :* ::* : .***:*** * ", "identical_positions": 131, "similar_positions": 157, "identity": "26.31%" }, { "cls_id": "homologset.agr.RGD:620849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70583-1", "uniprot_id": "DUT_RAT", "id": "P70583-1", "name": "Deoxyuridine 5'-triphosphate nucleotidohydrolase", "aln": "MPLLC-----------ALLRSRLQPS--------------------------LLRSLTLTSAQSLSCGGSRGVRTW--------SARTGPGACADPAVSVSKRAR-AEDD-ASLRFVRLSEHATAPTRGSARAAGYDLYSAYDYTIPSMEKALVKTDIQIAVPSGCYGRVAPRSGLAVKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERILY-PDLEEVQTLDNTERGSGGFGSTGKN----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ43-1", "uniprot_id": "DUT_MOUSE", "id": "Q9CQ43-1", "name": "Deoxyuridine 5'-triphosphate nucleotidohydrolase", "aln": "----------------------------------------------------------------MPCSED------------------------AAAVSASKRAR-AEDG-ASLRFVRLSEHATAPTRGSARAAGYDLFSAYDYTISPMEKAIVKTDIQIAVPSGCYGRVAPRSGLAVKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERISY-PDLEEVQTLDDTERGSGGFGSTGKN----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33316-3", "uniprot_id": "DUT_HUMAN", "id": "P33316-3", "name": "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "aln": "MTPLCPRPALCYHFLTSLLRSAMQNARGARQRAEAAVLSGPGPPLGRAAQHGIPRPLSSAGRLSQGCRGASTVGAAGWKGELPKAGGSPAPGPETPAISPSKRARPAEVGGMQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFY-PEIEEVQALDDTERGSGGFGSTGKN----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3I1-1", "uniprot_id": "Q9V3I1_DROME", "id": "Q9V3I1-1", "name": "Deoxyuridine 5'-triphosphate nucleotidohydrolase", "aln": "--------------------------------------------------------MPST---------------------------------DFADIPAAKKMK---IDTCVLRFAKLTENALEPVRGSAKAAGVDLRSAYDVVVPARGKAIVKTDLQVQVPEGSYGRVAPRSGLAVKNFIDVGAGVVDEDYRGNLGVVLFNHSDVDFEVKHGDRIAQFICERIFY-PQLVMVDKLEDTERGEAGFGSTGVKDLPAAKAQNGNGEKAAEPEGAAPAPVAT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33317-1", "uniprot_id": "DUT_YEAST", "id": "P33317-1", "name": "Deoxyuridine 5'-triphosphate nucleotidohydrolase", "aln": "--------------------------------------------------------------------------------------------------MTATSDK-------VLKIQLRSASATVPTKGSATAAGYDIYASQDITIPAMGQGMVSTDISFTVPVGTYGRIAPRSGLAVKNGIQTGAGVVDRDYTGEVKVVLFNHSQRDFAIKKGDRVAQLILEKIVDDAQIVVVDSLEESARGAGGFGSTGN-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : *:: : * *.:*** *** *: :: * .:.. :.:*.**:.. :* * ***:*******.*: *:.****:*.** *:: *****... .* :*:***:**:* *:* .:: *: *::: ** .****** ", "identical_positions": 61, "similar_positions": 49, "identity": "21.71%" }, { "cls_id": "homologset.agr.RGD:62085", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14455-1", "uniprot_id": "RL36B_YEAST", "id": "O14455-1", "name": "Large ribosomal subunit protein eL36B", "aln": "MAVKTGIAIGLNKGKKVT------------QMTPAPKISYKKG-------------AASNRTKFVRSLVREIAG--------LSPYERRLIDLIRNSGEKRARKVAKKRLG-SFTR------AKAKVEEMNNIIAASRRH--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P05745-1", "uniprot_id": "RL36A_YEAST", "id": "P05745-1", "name": "Large ribosomal subunit protein eL36A", "aln": "MTVKTGIAIGLNKGKKVT------------SMTPAPKISYKKG-------------AASNRTKFVRSLVREIAG--------LSPYERRLIDLIRNSGEKRARKVAKKRLG-SFTR------AKAKVEEMNNIIAASRRH--------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47964-1", "uniprot_id": "RL36_MOUSE", "id": "P47964-1", "name": "Large ribosomal subunit protein eL36", "aln": "MALRYPMAVGLNKGHKVT------------KNVSKPRHSRRRG-------------RLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LZ43-1", "uniprot_id": "A0ABK0LZ43_RAT", "id": "A0ABK0LZ43-1", "name": "60S ribosomal protein L36", "aln": "MALRYPMAVGLNKGHKVT------------KNVSKPRHSRRRG-------------RLTKHTKFVRDMIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNVLAAMRKAAAKKD---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6Q415-1", "uniprot_id": "RL36_DANRE", "id": "Q6Q415-1", "name": "Large ribosomal subunit protein eL36", "aln": "MVVRYPMAVGLNKGHKVT------------KNVSKPKHSRRRG-------------RLTKHAKFARDLIREVCG--------FAPYERRAMELLKVSKDKRALKFIKKRVG-THIR------AKRKREELSNTLAAMRKAAAKKE---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P49630-1", "uniprot_id": "RL36_DROME", "id": "P49630-1", "name": "Large ribosomal subunit protein eL36", "aln": "MAVRYELAIGLNKGHKTSKIRNVK--YTGDKKVKGLRGSRLKN-------------IQTRHTKFMRDLVREVVG--------HAPYEKRTMELLKVSKDKRALKFLKRRLG-THIR------AKRKREELSNILTQLRKAQTHAK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HME6-1", "uniprot_id": "ALT36_HUMAN", "id": "C0HME6-1", "name": "RPL36 alternative reading frame protein", "aln": "MASEAEGAGTRGSGPRELSRYSPPPLLPVAVRSHGPTLPYGRGPQQGPQSDQEREQAQAQPTPRASDQTHQVRAGHDSGGVWLCPVRAARHGVTEGLQGQTGPQIYQEKGGDAHPRQEEAGGAEQRTGRHEESCCQERLSPSPALSLK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * ..* : . :. :. : . ::: . .* . : . : . :. :.: * :. * *: : . .: * ", "identical_positions": 8, "similar_positions": 34, "identity": "5.41%" }, { "cls_id": "homologset.agr.RGD:620850", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55207-1", "uniprot_id": "ANFC_RAT", "id": "P55207-1", "name": "C-type natriuretic peptide", "aln": "MHLSQLIACALLLALLSLRPSEAKPGTPPKVPRTPPGEELAEPQAAGGNQKKGDKTPGGGGANLKGDRSRLLRDLRVDTKSRAAWARLLHEHPNARKYKGGNKKGLSKGCFGLKLDRIGSMSGLGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61839-1", "uniprot_id": "ANFC_MOUSE", "id": "Q61839-1", "name": "C-type natriuretic peptide", "aln": "MHLSQLIACALLLALLSLRPSEAKPGTPPKVPRTPPGEELADSQAAGGNQKKGDKTPGSGGANLKGDRSRLLRDLRVDTKSRAAWARLLHEHPNARKYKGGNKKGLSKGCFGLKLDRIGSMSGLGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23582-1", "uniprot_id": "ANFC_HUMAN", "id": "P23582-1", "name": "C-type natriuretic peptide", "aln": "MHLSQLLACALLLTLLSLRPSEAKPGAPPKVPRTPPAEELAEPQAAGGGQKKGDKAPGGGGANLKGDRSRLLRDLRVDTKSRAAWARLLQEHPNARKYKGANKKGLSKGCFGLKLDRIGSMSGLGC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:******:************:*********.****:.*****.******:**.******************************:**********.*************************", "identical_positions": 115, "similar_positions": 11, "identity": "91.27%" }, { "cls_id": "homologset.agr.RGD:620851", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16067-1", "uniprot_id": "ANPRB_RAT", "id": "P16067-1", "name": "Atrial natriuretic peptide receptor 2", "aln": "----------------------------------------------------------------MALPSLLLVVAALAGGVRP--PGARNLTLAVVLP--EHNLSYAWAWPRVGPAVALAVEALG-----RALPVDLR-FVSSELDGACSEYLAPLRAVDLK-LYHDPDLLLGPGCVYPAASVARFASHWHLPLLTAGAVAS-------------------------GFAAKNEHYRTLVR-TGPSAPKLGEFVVTLHGHFNWTARAALLYLDAR--TDDRPHYFTIEGVFEALQGSNLSVQHQVYTRE-PGGPEQATHFIRANGRIVYICGPLEMLHEILLQAQRENLT-NGDYVFFYLDVFG--ESLRAGPTRATGRPWQDN--R-TQEQAQALREAFQTVLVITYREPPNPEYQEFQNRLLIRAREDFGVELAPS-LMNLIAGCFYDGILLYAQVLNETIQEGGTRE----DGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLESGDFQPAAHYSGAEKQIWWTG-RPIPWV--KGAPPLDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFRKLMLEKELASMLWRIRWEELQFGNS----DRYHKGAGSRLTLSLRGS----SYGSLMTAHGKY-QIFANTGHFKGNVVAIKHVNKKRIE--LTRQVLFELKHMRDVQFNHLTRFIGACIDPPN--ICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFR-------STAEPDDSHALYAKKLWTAPELLSGNP--LPTTGMQKADVYSFAIILQEIALRSGPFYLEG--LDLSPKEIVQKVR----NGQRPYFRPSID-RTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKEGGTS-ILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGERKGPPGLL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6VVW5-1", "uniprot_id": "ANPRB_MOUSE", "id": "Q6VVW5-1", "name": "Atrial natriuretic peptide receptor 2", "aln": "----------------------------------------------------------------MALPSLLLVVAALAGGVRP--PGARNLTLAVVLP--EHNLSYAWAWPRVGPAVALAVEALG-----RALPVDLR-FVSSELDGACSEYLAPLRAVDLK-LYHDPDLLLGPGCVYPAASVARFASHWRLPLLTAGAVAS-------------------------GFAAKNEHYRTLVR-TGPSAPKLGEFVVTLHGHFNWTARAALLYLDAR--TDDRPHYFTIEGVFEALQGSNLSVQHQVYARE-PGGPEQATHFIRANGRIVYICGPLEMLHEILLQAQRENLT-NGDYVFFYLDVFG--ESLRAGPTRATGRPWQDN--R-TQEQAQALREAFQTVLVITYREPPNPEYQEFQNRLLIRAREDFGVELAPS-LMNLIAGCFYDGILLYAQVLNETIQEGGTRE----DGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWWTG-RPIPWV--KGAPPLDNPPCAFDLDDPSCDKTPLSTLAIVALGTGVTFIMFGVSSFLIFRKLMLEKELASMLWRIRWEELQFGNS----DRYHKGAGSRLTLSLRGS----SYGSLMTAHGKY-QIFANTGHFKGNVVAIKHVNKKRIE--LTRQVLFELKHMRDVQFNHLTRFIGACIDPPN--ICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFR-------STAEPDDSHALYAKKLWTAPELLSGNP--LPTTGMQKADVYSFAIILQEIALRSGPFYLEG--LDLSPKEIVQKVR----NGQRPYFRPSID-RTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKEGGTS-ILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGEQKGPPGLL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20594-1", "uniprot_id": "ANPRB_HUMAN", "id": "P20594-1", "name": "Atrial natriuretic peptide receptor 2", "aln": "----------------------------------------------------------------MALPSLLLLVAALAGGVRP--PGARNLTLAVVLP--EHNLSYAWAWPRVGPAVALAVEALG-----RALPVDLR-FVSSELEGACSEYLAPLSAVDLK-LYHDPDLLLGPGCVYPAASVARFASHWRLPLLTAGAVAS-------------------------GFSAKNDHYRTLVR-TGPSAPKLGEFVVTLHGHFNWTARAALLYLDAR--TDDRPHYFTIEGVFEALQGSNLSVQHQVYARE-PGGPEQATHFIRANGRIVYICGPLEMLHEILLQAQRENLT-NGDYVFFYLDVFG--ESLRAGPTRATGRPWQDN--R-TREQAQALREAFQTVLVITYREPPNPEYQEFQNRLLIRAREDFGVELGPS-LMNLIAGCFYDGILLYAEVLNETIQEGGTRE----DGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWWTG-RPIPWV--KGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFRKLMLEKELASMLWRIRWEELQFGNS----ERYHKGAGSRLTLSLRGS----SYGSLMTAHGKY-QIFANTGHFKGNVVAIKHVNKKRIE--LTRQVLFELKHMRDVQFNHLTRFIGACIDPPN--ICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFR-------STAEPDDSHALYAKKLWTAPELLSGNP--LPTTGMQKADVYSFGIILQEIALRSGPFYLEG--LDLSPKEIVQKVR----NGQRPYFRPSID-RTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTS-ILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGERKGPPGLL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B2U7-1", "uniprot_id": "A0A8M3B2U7_DANRE", "id": "A0A8M3B2U7-1", "name": "Guanylate cyclase", "aln": "----------------------------------------------------------MGSLLKMGYRVFIVLLTRMVVLECR--AEKGNITVAVMLP--EN-LKYSWASPRVLPAIRMAQEKIQKSGLLRGHTINLLNFSTEDSSGSCSENEAQIIAVDTK-LYHKPDAFIGPGCTYSVASVGRFASHWKLPLITAGGPAY-------------------------GFD-KWEEFKTIVR-TGPTTKKLGDFVNYLHGQFNWSSRALMIFHDLK--QDDRPHYFLSEGIYTVLREENITVLAFPYEDEQTYNYKDMITFIKDNGRIVYICGPLPTFFQIMKLFEDEVKS-PEDYAIFYLDVFA--ESLSG----DVPMPWQG-----SDIQWNDPIKLFQSVFVVTYQEPDSPEYTAFRKELHKRAIQDFNVQLEPS-MMDFIAGCFHDGFVLYAKALSEALADGVSQN----DGINITARMQNRRLWGVTGLVSIDQKNARFTDFSLWAMTNLKSGQYAIVGHYNGTSKEILWSPTEKIQWP--KGCPPLDYPPCGFSP----CKEDHLPVLGIVAVGSGLALIIFGISSFLIYRKLKLEKELAGMLWRIRWEELQFESP----NKYHKRAGSRLTLSQRGS----SYGSLITAHGKY-QLFAKTGYFKGNLVAIKHVNKKRIE--LTRQVLFELKHMRDVQFNHLTRFIGACIDPPN--ICIVTEYCPRGSLQDILENESINLDWMFRYSLINDIVKGMNYLHNSYIGSHGNLKSSNCVVDSRFVLKITDYGLASFR-------SSCENEDSHALYAKKLWTAPELLIYDR--HPPQGTQKGDVYSFGIILQEIALRNGPFYVEG--MDLSPKEIIQKVR----NGQKPYFRPTTD-NSRHCEELTILMEGCWSEDPAERPDFSHIKVFIAKFNKEGSTS-ILNNLLSRMEQYANNLENLVEERTQAYLEEKRKAENLLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSMSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHAREIAGMSLALLEQVKTFKIRHRPNDQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESTGEALRIHMSSATKEVLDEFGYFELQLRGDVEMKGKGKMRTYWLLGEKTDVYVI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF17-1", "uniprot_id": "Q9VF17_DROME", "id": "Q9VF17-1", "name": "Guanylate cyclase", "aln": "MPQAGQGLSLLLILCL--LQAHLFP---SAAWFYDAESVGGVASIGVGSDEHSFKTPETKNSHKSQSTELVQHFPSLPMPDHRRLGARRQLVFVALLPSVESDNKNDCIMPKVLPVLELAIRHVQRMGFVGGSHFDIQ-LISRDT--FCSSKYGPIGFFEIYTQWPEVNAVFGLPCEYVLAPISRYADVWQVPVLTTGGNAK-------------------------EFNKKSESYSTLTRLKGAQVNNLGNVVRAILNSFNWTRTALIYQNENAKVKGNSVCFLCLAAIHDTIEEHSVYQLGFDTSTWTKADITRMLKNVAMQSRIVIMCADPQSIRQIMLTAEELNMIDSGEYVFINIELFSRVQYL-------TSQPWYDK--NDTDLNNERAQKAYTAMLTVTPKQPNDNEYTRVSNEIKAIAAEKYNYTFSDNEPISAFVTSFFDGVLLYANALNESIREDPTMLTRPINGTDMVRRMWNRSFTGITGNVTIDANGDRLSAYSLLDMN-PTTGRFEIVAHFLHNRLEFEANKEIHWAGD--REEAPPDRPICGYDG--ALCPDNSLPGYAILSIVLGTMVVVMAVCFFFGYRHYIAEAEINSMSWKVSLEDVMFRDA----AERGLRG-SFHSLVKQSSQLTLMSEDMVSINGDR-QIFIPVGMFRKSKVAIKPVEVDNVQGLLTRSLMLELKRMKDLQHDHLVKFYGACLDQRR--SFLLTEYCPKGSLQDILENEQFQLDWMFRLSLMHDIVRGMQFLHSSDIRSHGNLKSSNCVVDSRFVLKITDFGLHTLRRTRFDLESDGGNCNSHAYWSKLLWTAPELLRVEHN-RPPEGTQKGDVYAFGIIVHEITTRQGPFYLGRCAYEKSPQEIIELVKGYNPHRMQKPFRPELEPNGDTKADINGIIRRCWAEDPAERPDFNTLKSMIRRFNKDNETGNIVDNLLKRMELYANNLEELVEERTQDYHEEKKKCEKLLYQLLPQSVAAQLISGQPVVAETFDQVTIYFSDIVGFTAISAESTPMQVVQFLNDLYTCFDSIVENFDVYKVETIGDAYMVVSGLPIRNGNQHAREIARLALALLEAVHNFRIHHRPEDRLKLRIGLHTGACVAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHISETTKEALDEFGTFVTTRRGFVPMKGKGEMLTYWLEGEVPRPNSLISPSKLMLTRRSSLKQPQRSQSHNLHKQYSELVVASPPPQLPPPAIALPPPPSPSKDSPNLRVKRKISSSSPKLNGGGFDYHKTENHYLDTAAAAQRNCDIYSSRSLRDMEETSDSWELAHFRLPLSGALKSHHHLNNNSHGYVHSNSSSNLSGILQPPPLGVQRTRLKPSPTISTLLTSARSEANASPGPETGSMGSGQLRIKFAEGDETPLLPTPPPLAAPPPIPQMVAASPQRSGSGQNIPADSSHYGFLVKSYKQQCPPVAGSAVTQPLLAKINS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MLX0-1", "uniprot_id": "Q8MLX0_DROME", "id": "Q8MLX0-1", "name": "Guanylate cyclase", "aln": "MHLLGISIHFFFLMYVNCFSAHPNPRRNDITWDDLNKDISLDSTTSLAGLNASDAGLEQRMYERSRESKSTQLSRYTEVGEMG--STMRVYNVGVLMA---SHLDSPFDLERCGPAVDLALDEIN---KVFLKPHNITLLKKKGSYPSCSGARAPGLAADMY-FQDDVIAFIGPACAFALEPVARLAAYWNKPIITGMGDQPPSSEGELTVTSGILGRIHKWKNENTGMFKDKSKYPTLTR-MSYCQCRLILVFASVIRQFNWNHVALLVD------RSELFSWTVGKNLEYGLRQEGLLSFVKELNGNEEEVYENYLKDASMYARVVILSVRGVLVRKFMLAAHSLGMT-NGEWVFLDVEIFQ-------------SEYWGDKGWEMKDEHDAKARKAYEALLRVSLLQPTSPKFQDFADNVRENALYDYNYTFGEGEEVNFFIGAFYDGVYLLGMALNETLTEGGDIR----DGVNITRRMWNRTFEGITGHVRIDDNGDRDADYSILDLD-PINGKFSVVAHYSGVHKVYSAVHGKKIHWPGGREEPPPDVPPCGFLGNSTDCVGN-FSTIMYSVFGLLLFLGLVFLVICLLQKQMKLSKELNNMSWRVRPDDVLIEMGGMFGSKGGLQRLDVENISLQQFGIHSGRASIASFTSLPPQVYTTIGQFKGERVAIKKVNVKKVD--LTPQLLWEIKQARDVSHENTVRFVGACIDLPRPTVLILTEYCSRGSLKDVLENEAIELDWNFRMSLIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGRFVLKISDFGLRTLT-------TPSDFVRDQNYYLKLLWIAPELLPLTTIPGCCPATQRGDVYSFGIILEEIVNRGGPYQEAR--QQMDVHTILHKVR------QCNGFRPLIR-ERECPPDLLELMEKCWADNQEERPTFSTIRSNIRTIMKGFCEN-LMDDLLNRMEQYANNLESLVEEKTRQLSLEKQRTEELLYQILPRPVAQQLMAGDLVEPEEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYDVYKVETIGDAYLVVSGLPEPNGDKHAREIALMALDILRAVSSFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVELKGKGTVTTYWLNSTSEGEARPPTPQILTTDEVPFPLLFAGMGK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .::. . : *.: :* : :: : . ** . : . .:* * : .:.* * *. *::* . : . . : *:.* . .* .. : ***. * : .: : : :. .: .*:* :. . ::: . ::.:: :::* * . . : : : ::: :: :* . :: . ..: * .:. : . :. : .*.**. * . .*.*:: :. :* :. :* .* *:** * :* :. * : : : : .* : ..*: : .* * * *.: * :. . . :. : : :: . *: .* *:: ::: : . . .: : .: : . *:: * *: . **** *: ..:: ** .:: *:*: :*:..:: .:* ***:* . ::****.:***:*:***: ::*** ** **::*:*:** :**.* : :**.*:*.**::*.******:*:** :: : .: : * ** ***** . *:.***:*.**:.**. * **: : . : *:. *: *** . :: ::. **::: *** *. :: * : * . ::::** *** ******.****:*: **:: * ****:**:.** ** *: * .* *..************ :.*.*:*::** :*****: ** *: :************:****** **. ** *** ::* :* * .*.::*:*. ::::***:*:*. ***** ***:****************.*:. :**:*.:** **::* * ** * :**** : **** . ", "identical_positions": 280, "similar_positions": 293, "identity": "19.01%" }, { "cls_id": "homologset.agr.RGD:620852", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ER30-1", "uniprot_id": "KLH41_RAT", "id": "Q9ER30-1", "name": "Kelch-like protein 41", "aln": "MDSQRELAEELRLYQSTLLQDGLKDLLEEKKFIDCTLKAGDKSFPCHRLILSACSPYFREYFLSEIEEEK---KKEMALDNVDPAILDLIIKYLYSASIDLNDGNVQDIFALSSRFQIPSVFTVCVSYLQKRLAPGNCLAILRLGLLLDCPRLAISAREFVSDRFVQICKEEDFMQLSPQELISVISNDSLNVEKEEVVFEAVMKWVRTDKENRAKNLSEVFDCIRFRLMAEKYFKDHVEKDDIIKSNPEVQKKIKVLKDAFAGKLPEPSKSAEKGGTGEVNGDVGDEDLLPGYLNDIPRHGMFVKDLILLVNDTAAVAYDPMENECYLTALAEQIPRNHSSIVTQQNQVYVVGGLYVDEENKDQPLQSYFFQLDNVSSEWVGLPPLPSARCLFGLGEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWSEVKNLPIKVYGHNVISHNGMIYCLGGKTDDKKCTNRVFIYNPKKGDWKDLAPMKTPRSMFGVAIHKGKIVIAGGVTEDGLSASVEAFDLKTNKWEVMTEFPQERSSISLVSLAGSLYAIGGFAMIQLESKEFAPTEVNDIWKYEDDKKEWAGMLKEIRYASGASCLATRLNLFKLSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AUC9-1", "uniprot_id": "KLH41_MOUSE", "id": "A2AUC9-1", "name": "Kelch-like protein 41", "aln": "MDSQRELAEELRLYQSTLLQDGLKDLLEEKKFIDCTLKAGDKSFPCHRLILSACSPYFREYFLSEIEEEK---KKEVALDNVDPAILDLIIKYLYSASIDLNDGNVQDIFALSSRFQIPSVFTVCVSYLQKRLAPGNCLAILRLGLLLDCPRLAISAREFVSDRFVQICKEEDFMQLSPQELISVISNDSLNVEKEEVVFEAVMKWVRTDKENRAKNLSEVFDCIRFRLMAEKYFKDHVEKDDIIKSNPEVQKKIKVLKDAFAGKLPEPSKNAEKAGAGEVNGDVGDEDLLPGYLNDIPRHGMFVKDLILLVNDTAAVAYDPMENECYLTALAEQIPRNHSSLVTQQNQVYVVGGLYVDEENKDQPLQSYFFQLDNVTSEWVGLPPLPSARCLFGLGEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWSEVKNLPIKVYGHNVISHNGMIYCLGGKTDDKKCTNRVFIYNPKKGDWKDLAPMKTPRSMFGVAIHKGKIVIAGGVTEDGLSASVEAFDLKTNKWEVMTEFPQERSSISLVSLAGALYAIGGFAMIQLESKEFAPTEVNDIWKYEDDKKEWAGMLKEIRYASGASCLATRLNLFKLSKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60662-1", "uniprot_id": "KLH41_HUMAN", "id": "O60662-1", "name": "Kelch-like protein 41", "aln": "MDSQRELAEELRLYQSTLLQDGLKDLLDEKKFIDCTLKAGDKSLPCHRLILSACSPYFREYFLSEIDEAK---KKEVVLDNVDPAILDLIIKYLYSASIDLNDGNVQDIFALASRFQIPSVFTVCVSYLQKRLAPGNCLAILRLGLLLDCPRLAISAREFVSDRFVQICKEEDFMQLSPQELISVISNDSLNVEKEEAVFEAVMKWVRTDKENRVKNLSEVFDCIRFRLMTEKYFKDHVEKDDIIKSNPDLQKKIKVLKDAFAGKLPEPSKNAAKTGAGEVNGDVGDEDLLPGYLNDIPRHGMFVKDLILLVNDTAAVAYDPTENECYLTALAEQIPRNHSSIVTQQNQIYVVGGLYVDEENKDQPLQSYFFQLDSIASEWVGLPPLPSARCLFGLGEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWNEVKKLPIKVYGHNVISHKGMIYCLGGKTDDKKCTNRVFIFNPKKGDWKDLAPMKIPRSMFGVAVHKGKIVIAGGVTEDGLSASVEAFDLTTNKWDVMTEFPQERSSISLVSLAGSLYAIGGFAMIQLESKEFAPTEVNDIWKYEDDKKEWAGMLKEIRYASGASCLATRLNLFKLSKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QEG2-1", "uniprot_id": "KL41B_DANRE", "id": "F1QEG2-1", "name": "Kelch-like protein 41b", "aln": "MDP-KAIKEELRLFQSTLLQDGLKELLNENKFVDCTLKIGDRCFPCHRLIMAACSPYFRELFFSEDGKEK-DIGKEVVLDDVDPNIMDMILQYLYSAEIDLVDDNVQEIFAVANRFQIPSVFTVCVNYLQQKLSMANCLAVFRLGLVLSVPRLAIAARDFIADRFETVSSEEEFLQLAPHELLALIGGDMLNVEKEEVVFESVMKWVRNDKANRVKSLAEAFDCIRFRLLPEKYFREKVETDDIIKGDPELLKKLQLVKDAFKGKLPE-KKPKEKK-EGEVNGEEEGEEMLPGFLNDNRRLGMYGRDLIVMINDTAAVAYDVVENECFLAAMAEQVPKNHVSLCTKKNQLFIVGGLFVDEESKESPLQCYFYQLDSFSSDWRALPPMPSPRCLFNLGESENLLFAIAGKDLQTNESLDSVMCFDTERMKWSETKKLPLHIHGHSVVSHNNLVYCIGGKTDDNKALSKMFVYNHKQSEWRELASMKTPRAMFGAVVHKGKIIVTGGVNEDGLTALSETYDFDTNKWDTFTEFPQERSSVNLVSSGGNLFSIGGFAIVELEDKNIGPSEITDIWQYEEDKKTWSGMLREMRYASGSSCVGMRLNAARMPKL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9QIN8-1", "uniprot_id": "KL41A_DANRE", "id": "E9QIN8-1", "name": "Kelch-like protein 41a", "aln": "MEP-MSVKEDLRLFQSTLLQDGLKELLKENKFVDCILKVGDRSLPCHRLIMAACSPYFRELYFTEDGTEKKDANKEVVLENVDPNIMDMIVNYLYSADIDITDDNVQDVFAVANKFQIPSVFTVCVNYLQNKLSLGNCLAIFRMGLVLNCPRLAVSARDFIAEHFETLSKDEEFLEFNAPEFFAIIGCDALNVEKEELVFELLMKWVRKNKENRAKALGDAFEHIRFRLLPEKYLKEKVEKDDIIKADPELIKKLKVIKDAFAGKLPQ-IKEGEK--------EGEGENELPGFLNDSQRLGMFNRDLILMINDTAAVAYDANENECFLAAMAEQIPRNHVSITSKKNLLYVAGGLFVDEENKDSPLQCYFYQMDPHSPNWIALPPMPSPRCLFAMGEFENLLFAVAGKDLQSNESLDSVLCYDVDKMKWLETKKLPLRIHGHSVISQNGLVYCIGGKTDENKTINKMFAYNHKKSEWKELAAMKTPRSMFGATVHKGKIVVVGGVNEDGLLSSCEAYDFGTNKWEVFAEFAQERSSVNVLSVDGVLYAVAGFTIKENEDKQCVPSEITDIWQYEEDKKQWSGMIGEMRYASGASCVSMRLNVAKMPKL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. : *:***:**********:**.*:**:** ** **:.:******::******** :::* * **:.*::*** *:*:*::*****.**: *.***::**::.:***********.***::*: .****::*:**:*. ****::**:*::::* :..:*:*::: . *::::*. * ******* *** :*****.:* **.* *.:.*: *****:.***::::**.*****.:*:: **::::**** ****: * * : .*: ***:*** * **: :***:::********* ****:*:*:***:*:** *: :::* :::.***:****.*:.***.**:*:* :.:* .***:**.**** :** :: ::.:******:: *****:*:* ** *.*:**::::**.*:*::.::**:*****::* .::* :* *:.:*::**.** **:***..:*****::.***.**** : *::*: ****:.::**.*****:.::* * *:::.**:: : *.*: *:*:.***:**:*** *:**: *:*****:**:. *** ::.**", "identical_positions": 314, "similar_positions": 205, "identity": "51.56%" }, { "cls_id": "homologset.agr.RGD:620853", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35827-1", "uniprot_id": "APBB3_RAT", "id": "O35827-1", "name": "Amyloid-beta A4 precursor protein-binding family B member 3", "aln": "MLGKDYMLAIILVNCDDDLWGDQNLEGETGLPPGWRKIRDAAGTYYWHVPSGSTQWQRPTWEL--AEDPGTGKEGIWELRPPKGRSFSS---LDSSLNRSNSLTWYNEDSYVRSLEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQARNRSQPHDGAWGEGQNMLMVLKKDAMSLLNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVAGDKDSCMLKCHVFRCDVPAKAIASRLQGLCAQILSERVGLS-GEAACCSPDPISPEDFPRQVELLDAVSQAAQKYEALYMGILPVTKAMGMDVLNEAIGTLTGRGDRKTWVPAMLSVSDSLMTAHPIQAEAGAEEEPLWQCPVRLVTFIGVGHDPHTFGLIADLGCQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVAS--AARGKAWGAQARARLRLKRTSSMDSPGGPLPPPLLKGGVGGAGAAPRKRGVFSFLDAFRLKPLFSICPKLILEGWGKRLYTLPVPRVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1C9-1", "uniprot_id": "APBB3_MOUSE", "id": "Q8R1C9-1", "name": "Amyloid-beta A4 precursor protein-binding family B member 3", "aln": "MLGKDYMLAIILVNCDDDLWGDQNLEGETGLPPGWRKIRDAAGTYYWHVPSGSTQWQRPTWELPGAEDPGRGTEGIWELRPPKGRSFSS---LDSSLNRSNSLTWYSEDSYVRSLEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRNRSQPHDGTWGEGQNMLMILKKDAMSLLNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVAGDKDSCMLKCHVFHCDVPAKAIASALQGLCAQILSERVGVS-GEAACCSPDPISPEDLPRQVELLDAVSQAAQKYEALYMGILPVTKAMGMDVLNEAIGTLTARGDRKTWVPAMLSVSDSLMTAHAIQAEAGAEEEPLWQCPVRLVTFIGVGRDPHTFGLIADLGCQSFQCAAFWCEPHAGGLSEAVQAACMVQYQKCLVAS--AARGKAWGAQARARLRLKRTSSMDSPGGPLPPPLLKGGAGGAGAAPRKRGVFSFLDAFRLKPSLLHMS--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95704-1", "uniprot_id": "APBB3_HUMAN", "id": "O95704-1", "name": "Amyloid-beta A4 precursor protein-binding family B member 3", "aln": "MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPTWELGDAEDPGTGTEGIWGLRPPKGRSFSS---LESSLDRSNSLSWYGGESYIQSMEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMSLVNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVASDKDSCMLKCHVFCCDVPAKAIASALHGLCAQILSERVEVS-GDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALYMGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVAS--AARGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDAFRLKPSLLHMP--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FF73-1", "uniprot_id": "E7FF73_DANRE", "id": "E7FF73-1", "name": "Amyloid-beta A4 precursor protein-binding family B member 3", "aln": "MLGKDYMLAIIIVNYDDNIWNDQSLELDSDLPPGWRTIRDSTGTYYWHVPTGTTQWQHPSYSAEEEQNAINGVTASQIKLAADGRRESRGRLTENPLPSLSERPSWQEEYFCANMDPDSKCFAVRSLGWVEIPEEELTPGKSSLAVNNCIQQLSHSKAEGRDAEGAWGEGQDMMMVLKKDTLSLMDPVDQSLIHCQPIINIRVWGVGCNNGR--DFAFVASDKDTCMLKCHVFRCNAPAKTIASALHEMCSKIMTEKAALQPSMARSLTMESISPEDLPRQVDFLEAVRQRVQKFEVEYIGNLPVSRAMGMEVLNRAIESIMHSRDRDEWEPIVIHVSDTVLS--LWRGEDGD--DPFWESQVRYLTFLGVGHDTHTFAVIVDAGTQRFECHVFWCEPDAGIISEAVQAACMVQYQKCLVAQTPPVRPKIW----RAGSKVKRANSMD--GSSFPPRYQGHTASKMTSPSVKKGMLAFFETFRNKHSAVSTP--------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********:** **::*.*:.** ::.******.*:*::********:*:****:*::. ::. * . ...** * :..* .. . : : : .::*.:************:***:*:*****:*********:::: ..: :*:*****:*:*:****::**::*:*:*******:::*******..:** ******.***:******** *:.***:*** *: :*::*::*:. :. . * . : :.*****:****::*:** * .**:*. *:* ***::****:***.** :: **. * * :: ***:::: :.* . :*:*:. ** :**:***:*.***.:*.* * * *:* .***:*.** :******************. ..* * * ** ::**:.*** *..:* .. :.. *:*:::*:::** * . ", "identical_positions": 237, "similar_positions": 151, "identity": "46.29%" }, { "cls_id": "homologset.agr.RGD:620854", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54838-1", "uniprot_id": "DUS5_RAT", "id": "O54838-1", "name": "Dual specificity protein phosphatase 5", "aln": "MKVTSLDGRRLRKMLRKEAEARCVVLDCRPYLAFAASSVRGSLNVNLNSVVLRRARGGAVSARYVLADEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLSAGPRVYFLKGGYETFYSQYPECCVDAKPISQEKLEGERGLLSQCGKPILSVAYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACTTHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREEGGKVLVHCEAGVSRSPTICMAYLMKTKQFRLKEAFEYIKQRRSVVSPNFGFMGQLLQYESEILPSTPTPQPPSCQGEAASSTFIGHLQTLSPDMQGAYCTFPTSVLAPVPTHATVAELHRSPVATATSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1HL35-1", "uniprot_id": "Q1HL35_MOUSE", "id": "Q1HL35-1", "name": "Dual specificity protein phosphatase", "aln": "MKVTSLDGRQLRKMLRKEAEARCVVLDCRPYLAFAASSVRGSLNVNLNSVVLRRARGGAVSARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFLKGGYETFYSQYPECCVDVKPTSQEKIEGERSLLSQCGKPVLSVAYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACTTHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREEGGKVLVHCEAGVSRSPTICMAYLMKTKQFRLKEAFDYVKQRRSVVSPNFGFMGQLLQYESEILPSTPTLQPPSCQGEAASSTFIGHLQTLSPDMQGTYCTFRTSVLAPVPTHSTVPELHRSPVATATSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16690-1", "uniprot_id": "DUS5_HUMAN", "id": "Q16690-1", "name": "Dual specificity protein phosphatase 5", "aln": "MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFLKGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATATSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBT4-1", "uniprot_id": "Q6PBT4_DANRE", "id": "Q6PBT4-1", "name": "Dual specificity protein phosphatase", "aln": "MKVSSIDCRRLRKIIRKECGN-CLIVDCRPYFSFSNSCIRGSVNVNLNSVVVRRSRGGPVPLQFVIPDEKALFRLRE---GSISAVVALDDRTPHLQKLKKDSIAQIVIN-TLSHLTSSASICFLKGGYENFHAHYPELCTETRSVEVSEDKSERGVSSHCDK--LASHHKPDYDQGRPVEILPFLYLGSAYHACRQDYLSDLHITALLNVSRRDSRPARGQYNYKWIPVEDSHTADISSHFQEAIDFIERVKAEGGKVLVHCEAGISRSPTICMAYIMKTQRLRLEQAFDVIRQRRAIISPNFSFMGQLLQFESEVVSSTPPLVTPAAQ--ETPTFFSGDFTLETESFESSVFTFPTSFLTPIQPSFKLSPITALP-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*:* *:***::***. *:::*****::*: * :***:********:**:***.*. ::*:.** * ** : *.::***.**: : * ***:::* *::*:. *: *.:.. : *******.*::.*** *.:.:. . .: :.**.: *:*.* : ::* **** ****************.: ::*::************ *... : :*************************: *: :***********:**********:***:::**::**: ::***:::****.*******:***::.*** .*:.* : : : *.: : .::.: ** :*.*:*: . .:. : * ", "identical_positions": 193, "similar_positions": 118, "identity": "50.26%" }, { "cls_id": "homologset.agr.RGD:620855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54921-1", "uniprot_id": "SNAA_RAT", "id": "P54921-1", "name": "Alpha-soluble NSF attachment protein", "aln": "MDTSGKQAEAMALLAEAERKVKNSQSFFSGLFGG-SSKIEEACEIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKAD-PQEAINCLMRAIEIYTDMGRFTIAAKHHISIAEIYETELVDVEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAAQLEQYQKAIDIYEQVGTSAMDSPLLKYSAKDYFFKAALCHFC-IDMLNAKLAVQKYEELFPAFSDSRECKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DB05-1", "uniprot_id": "SNAA_MOUSE", "id": "Q9DB05-1", "name": "Alpha-soluble NSF attachment protein", "aln": "MDNSGKQAEAMALLAEAERKVKNSQSFFSGLFGG-SSKIEEACEIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKAD-PQEAINCLMRAIEIYTDMGRFTIAAKHHISIAEIYETELVDVEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAAQLEQYQKAIDIYEQVGTSAMDSPLLKYSAKDYFFKAALCHFC-IDMLNAKLAVQKYEELFPAFSDSRECKLMKKLLEAHEEQNVDSYTEAVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54920-1", "uniprot_id": "SNAA_HUMAN", "id": "P54920-1", "name": "Alpha-soluble NSF attachment protein", "aln": "MDNSGKEAEAMALLAEAERKVKNSQSFFSGLFGG-SSKIEEACEIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKAD-PQEAINCLMRAIEIYTDMGRFTIAAKHHISIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAALLEQYQKAIDIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFC-IDMLNAKLAVQKYEELFPAFSDSRECKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q23983-1", "uniprot_id": "SNAP_DROME", "id": "Q23983-1", "name": "Alpha-soluble NSF attachment protein", "aln": "MGDN--EQKALQLMAEAEKKLTQQKGFLGSLFGG-SNKVEDAIECYQRAGNMFKMSKNWTKAGECFCEAATLHARAGSRHDAGTCYVDASNCYKKVD-VESAVNCLMKSIDIYTDMGRFTMAAKHHQSIAEMYESDPNNLAKSIQHYEQAADYFKGEESVSSANKCMLKVAQYAAQLEDYEKAISIYEQVAASSLESSLLKYSAKEYFFRAALCHLS-VDLLNAQHAIEKYAQQYPAFQDSREFKLIKVLCENLEEQNIEGFTEAVKDYDSISRLDQWYTTILLRIKKAAD-EDPDLR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32602-1", "uniprot_id": "SEC17_YEAST", "id": "P32602-1", "name": "Alpha-soluble NSF attachment protein", "aln": "------MSDPVELLKRAEKKGVPSSGFMKLFSGSDSYKFEEAADLCVQAATIYRLRKELNLAGDSFLKAADYQKKAGNEDEAGNTYVEAYKCFKSGGNSVNAVDSLENAIQIFTHRGQFRRGANFKFELGEILENDLHDYAKAIDCYELAGEWYAQDQSVALSNKCFIKCADLKALDGQYIEASDIYSKLIKSSMGNRLSQWSLKDYFLKKGLCQLAATDAVAAARTLQEGQSEDPNFADSRESNFLKSLIDAVNEGDSEQLSEHCKEFDNFMRLDKWKITILNKIKESIQQQEDDLL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: *: .**:* ...*: : *. * *.*:* : :*..:::: *: . **:.* :** : : ...:*.. :*:* :.:*. . .*::.* .:*:*:*. *:* .*:.: .:.*: *.: : *:* ** :.::: ::* : :***::* * * :* :* .**.:: .:: . * ::* *:**:: .**::. * : * :::: . * * **** :::* * : :* : : :* *::*.: ***:* *:* :**:: : :: ** ", "identical_positions": 77, "similar_positions": 120, "identity": "25.84%" }, { "cls_id": "homologset.agr.RGD:620856", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KA15-1", "uniprot_id": "A0A0G2KA15_RAT", "id": "A0A0G2KA15-1", "name": "General transcription factor II-I repeat domain-containing protein 1", "aln": "MALLGKH-CDIPTNGCGSERWNSTFARKDELINSLVSALDSMCSALSKLNTEVACVAVHNESVFVMGTEKGRVFLNTRKELQSDFLRFCRGPLWNDPEAGHPK---------KVQRCEGGGRSIPRSSLEQCSDVYLLQKMVEEVFDVLYSEAMGRATVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLRRPPDDGGQDTKALVEMNGISLLPKGSRDCGLHGQASKVSPQDLTPTATPSSMANFLYSTSMPNHTIRELKQEVPTCPLTPSDLGLGWP-VPEPHVPSTQDFSDCCGQ-APAGPAGPLIQN---VHASKRILFSIVHDKSEKWDPFIKEMEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGN-KFTKDPMKLEPASP----PEDTATEVCRDSMLDLAGTAWSDMSSVS--EDCGPGTSGEIGMLRPIKIEPEELDIIQVTVSDPSPTSEEMTDSLPGHLPSEDSGYGMEMPADKGPSEEPWQEERPAEESPGDVIRPLRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTDGVKEPVMDTQ---------------ERDSWDPLVDETP--KRQGLQENYNTRLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTRPFQGLIPKP---------------------------DEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKARDHVRMVIINQLQPFTEVCNDP-------------------------------------------------------------------------------------------------------KVPAKDN-IPKRKRKRVSEGNSVSSSSSSSSSSSSNPESVASTNQISLVQ------------WPVYMVDY-------SGLNVQLPGPLDY-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JI57-1", "uniprot_id": "GT2D1_MOUSE", "id": "Q9JI57-1", "name": "General transcription factor II-I repeat domain-containing protein 1", "aln": "MALLGKH-CDIPTNGCGSERWNSTFARKDELINSLVSALDSMCSALSKLNTEVACVAVHNESVFVMGTEKGRVFLNTRKELQSDFLRFCRGPLWNDPEAGHPK---------KVQRCEGGGRSLPRSSLEQCSDVYLLQKMVEEVFDVLYSEAMGRATVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLRRPPDDGGQDTKALVEMNGISLLPKGSRDCGLHGQASKVAPQDLTPTATPSSMANFLYSTSMPNHTIRELKQEVPTCPLTPSDLGMGWP-VPEPHVPSTQDFSDCCGQ-TPAGPAGPLIQN---VHASKRILFSIVHDKSEKWDPFIKEMEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGN-KFTKDPMKLEPASP----PEDTSTEVCRDSMLDLAGTAWSDMSSVS--EDCGPGTSGEIAMLRPIKIEPEELDIIQVTVSDPSPTSEEMTDSLPGHLPSEDSGYGMEMPADKGPSEEPWSEERPAEESPGDVIRPLRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTDGVKEPVLDTQ---------------ERDSWDRLVDETP--KRQGLQENYNTRLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTRPFQGLIPKPETKILTTGHEAGKTTRPRRLQQDTWQPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEVCNDPKVPEEDDSNKLGKKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFGDVCNNAKVPAKDN-IPKRKRKRVSEGNSVSSSSSSSSSSS-NPESVASTNQISLVVKSRGSELHPNSVWPLPLPRAGPSTAPGTGRHWALRGTQPTTEGQAHPLVLPTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHL9-1", "uniprot_id": "GT2D1_HUMAN", "id": "Q9UHL9-1", "name": "General transcription factor II-I repeat domain-containing protein 1", "aln": "MALLGKR-CDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPK---------KVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRP-MPEPKATGAQDFSDCCGQ-KPTGPGGPLIQN---VHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGN-KFTKDTTKLEPASP----PEDTSAEVSRATVLDLAGNARSDKGSMS--EDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESL--KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKP---------------------------DEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDA-------------------------------------------------------------------------------------------------------KVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISLVQ------------WPMYMVDY-------AGLNVQLPGPLNY-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLI6-1", "uniprot_id": "A0A8M9PLI6_DANRE", "id": "A0A8M9PLI6-1", "name": "", "aln": "MAQIRKLGCDGMRTNSRPELKVPQVSARQEILTSLVSALDSVCSAMSKLNAEVACVTVHEDSVIAVGTEKGRIFLNSRKEIQTDFHKFCKVSCLQALNSMNSHSKVPEVDCSRTGKDSSGQQGRQRALTDTHSNIFVLRKMVEEVFSVLYSEAVGKSSLVPVPYDWILKDPSSVVVYGLPDGVTLRKPSEYDTKTLMKILEQSNRIRFIVKRTPEEPSRDAKSCPEVNHHSSTSKSAS------NHTSVKPSVQEVSASNSMLSSFLYGMPMSSQPHPDSKLDLKPTSLHS--IGKERPGMWTPAEEKAVQAKECADNGERIGLAADLTQSPPSIHVSKRLLFSIVHEKSEKWDSFIRETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHAVRFVVRRMFDERIFTAAGKVAKEEGKQDGPASEDGFPEGLRIPSSSLELVSNTHSSRSTSSCVSPLAECEAGPSGDCLPLKKIKTEPPDGEIIQVTVPESSASTEESSEPQAERVTPDLCRPKEPVAEDLTPKSTPQGLKRAVEEDIGEMILQLRKQVESLFSCKYSEALGLPEPAKVPYSKFQMYPDDLYVTGLPEGMTFRRPNCFGAAKLRKILSASSQITFVITRPELLTEPVKNESVSKTTSES----------AETDSKDQSDDPGPASKRPGFSDSLEAKLSRIDLANTLREQVQDLFNRKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKISFSITRPFQGLIPKPAPRRITILKKG-----------YTPISEEDEVNRMGEKVILREQVKELFNKKYGEALGLDRSVIVPYKLIRANPGSLEVCGLPDDIPFRNPNTYDIVRLEKVLQAQDEITFNIKTPLQPFTELCTQS------------------------------------------------------------------------------------------------------CNKEGKEVSTNRRKRKRVLE--------SSQTSMPTAGDSALSTNQIPVMQ------------WPMYMVDY-------SGVNVQVPGKVKY-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : * ** ... .: . .: ::*::.********:***:****:*****:**::*.:.:******:***:***:*:** :**: . : :: :.: :. : ..* :. *: : *::::*:*******.******:*::::**:**: :*::*. :.* ***:*:::*:*:***.*:** ***:*:**** ::*. :: .:*:*: *:* * .*.: : ..* *. :*: * ::.***. .:..:. : * : . .* . :* * : * : : .:*..: * .. * *. :*.***:******:******.**:* ********************************************:***************************:::*:::*********. *.:*: * : .:. **. . ::. : .: * ..:* :* .*.**: *: ** ** : :******.:.*.::** ::. . ::..: . : * .. . :*..*:. *::* ****** **. :*::*:* .**.******* *:*::*:* *****:::******* *******.**..* ***.******: **: :.. * ** * * ** *:.:. :::*****:*************:****************************************************:*****.*::*********** :**:.**:***************:********:*.*:******* .*.::** **************** ****:*:*::.: : * . ****:*:*.:. : .*: :****** * **.:* . :*. *:***.:: **: : :* : : * ", "identical_positions": 484, "similar_positions": 266, "identity": "42.27%" }, { "cls_id": "homologset.agr.RGD:620857", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14423-1", "uniprot_id": "PA2GA_RAT", "id": "P14423-1", "name": "Phospholipase A2, membrane associated", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVLLLLAVVIMAFG--------------------SIQVQG-----SLLEFGQMILFKTGKRADVSYGFYGCHCGVGGRGSPKDATDWCCVTHDCCYNRLEKRGCGTKFLTYKFSYRGGQISCSTN------QDSCRKQLCQCDKAAAECFARNKKSYSLKYQFYPNKFCKGKTPSC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31482-1", "uniprot_id": "PA2GA_MOUSE", "id": "P31482-1", "name": "Phospholipase A2, membrane associated", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVLLLLAASIMAFG--------------------SIQVQG-----NIAQFGEMIRLKTGKRAELSYAFYGCHCGLGGKGSPKDATDRCCVTHDCCYKSLEKSGCGTKLLKYKYSHQGGQITCSAN------QNSCQKRLCQCDKAAAECFARNKKTYSLKYQFYPNMFCKGKKPKC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14555-1", "uniprot_id": "PA2GA_HUMAN", "id": "P14555-1", "name": "Phospholipase A2, membrane associated", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKTLLLLAV-IMIFG--------------------LLQAHG-----NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAK-------QDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IML0-1", "uniprot_id": "Q8IML0_DROME", "id": "Q8IML0-1", "name": "Phospholipase A2", "aln": "MLWIMGLVVAAVRLNGQASGAANVTVIEDIRSAFRGVTNDTELLNHIIPEMYGASMRSANPSFVFKMPSKSNGGGDDFELLTMQRSDFAEPIFPNISQSATAIDSPSTIPPETSVKTSLMVSPQQDWQQMGLDGWTGELKPPVASLEQDHRDTRPPISWQNSYPHDEIRLEFQNHHFDGRVTDIRVITQTTSKPAEMEDLMNVQNVYIARVNDPFGYSMKWSFTNDSSREKELLPEGDRGKRDVARLYSMIKCSTG-CDPLIYKGYGCYCGFGGHGVPADGIDRCCRVHDKCYGQSNCISYLEYFVPYVWKCYRGKPLCAVDHGEFGGPDSCAARLCQCDLRLSRCLKRYYCPHRRSICHSSRSRRLQNLIFFD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *: : : : .* .: .: ** .** : * ***:**.**:* * *. * ** .** ** : . :: * :. .: *: :** :**:** : *: * .: . . .. . ", "identical_positions": 35, "similar_positions": 38, "identity": "9.36%" }, { "cls_id": "homologset.agr.RGD:620858", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q791F6-1", "uniprot_id": "TPRA1_RAT", "id": "Q791F6-1", "name": "Transmembrane protein adipocyte-associated 1", "aln": "-MASLQEA---------------NGSTAWPPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIVGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESAGPACASAANYSSTQFDSAG-VAYLDDIASMPCH-TGSINSTDSERWKAINA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99MU1-1", "uniprot_id": "TPRA1_MOUSE", "id": "Q99MU1-1", "name": "Transmembrane protein adipocyte-associated 1", "aln": "-MASLQEA---------------NGSTAWPPPTASNISEPHQCLLLLYEDIGSSRVRYWDLLLLIPNVLFFIFLLWKLPLARAKIRVTSSPIFITFYILVFVVALVGIARAVVSMTVSASDAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDSHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERVSLPSRRSFYVYAGILATLNLLQGLGSALLCANIIVGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDEAEEPDMHLPQPYAVARREGIESAGPACASAANYSSTQFDSAG-VAYLDDIASMPCH-TGSINSTDSERWKAINA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86W33-1", "uniprot_id": "TPRA1_HUMAN", "id": "Q86W33-1", "name": "Transmembrane protein adipocyte-associated 1", "aln": "-MDTLEEVT------------WANGSTALPPPLAPNISVPHRCLLLLYEDIGTSRVRYWDLLLLIPNVLFLIFLLWKLPSARAKIRITSSPIFITFYILVFVVALVGIARAVVSMTVSTSNAATVADKILWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITTVLSLAYSVTQGTLEILYPDAHLSAEDFNIYGHGGRQFWLVSSCFFFLVYSLVVILPKTPLKERISLPSRRSFYVYAGILALLNLLQGLGSVLLCFDIIEGLCCVDATTFLYFSFFAPLIYVAFLRGFFGSEPKILFSYKCQVDETEEPDVHLPQPYAVARREGLEAAGAAGASAASYSSTQFDSAGGVAYLDDIASMPCH-TGSINSTDSERWKAINA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4V8X0-1", "uniprot_id": "TPRA1_DANRE", "id": "Q4V8X0-1", "name": "Transmembrane protein adipocyte-associated 1 homolog", "aln": "MLETVTDVASFVHYGNTSVFPTADNSSEIIPDGESNISKPHRCLQVLYDDIGTSRVRYWDVMLLIPNVAFLVFLMWKLPSARAKIRLTSSPIFVAFYILVFVVAAVGITRAIVSMTVSTSSAATLIDKVLWEITRFFLLAIELSVIILGLAFGHLESKSSIKRVLAITAVLSLAYSITQGTLEIRFPDKHLSAKDFNIYGHGGRHFWLASSCFFFLVYSLIVILPKTPIRERISLPSKRSFYVYSGILALLNLVQGLGSALLCADIIEGLCCVDVTTFLYFSVFAPLIYVTFLKGFFGSEPKILFSYKSQIDEPEDSDVHLPHTSSSG-------LGRKDLDRGSYSSTQIDGSG--AYLDDVVSGPFGGAHSINSVDSDRWRSINT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :. :.*: * .*** **:** :**:***:*******::****** *::**:**** ******:******::********* ***:**:******:*.***: **:***************************************:*******:******* :** ****:**********:***.***********:*******::**:****:******:**** ***:*****.*** :** ******.*******.*******:**:**************.*:**.*:.*:***:. : . * . ..*****:*.:* *****:.* * : ****.**:**::**:", "identical_positions": 260, "similar_positions": 70, "identity": "67.18%" }, { "cls_id": "homologset.agr.RGD:620859", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70239-1", "uniprot_id": "AXIN1_RAT", "id": "O70239-1", "name": "Axin-1", "aln": "--MNVQEQG--FPLDLGASFTEDAPRPPVPGEEGELVSTDSRPVNHSFCSGKGTSIKSETSTATPRRSDLDLGYEPEGSASPTPPYLRWAESLHSLLDDQDGISLFRTFLKQEG--CADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCVMKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGMSGYLPTLNEDEEWKCDQDADEDDGRDSVPPSRLTQKLLLETAAPRAPSSRRYNEGRELRYGSWREPVNPYYVNSGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRMPKEIRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGEMPSGP-MASHKLPSVPAWHHFPPRYVDMGCSG--LRDAHEENP-ESILDEHVQRVMRTPGCQSPGPG-----HRSPDSGHVAKT-AVLGGTASGHGKHAPKLGLKLDSAGLHHHRHVHHHVHHNSARPKEQMEAEAARRVQSSFSWGPETHGH-AKPRSYSESTGTNPSAGD-LAFGGKASAPSKRNTKKAESGKNASAEVPSTTEDAEKNQKIMQWIIEGEKEISRHRKAGHGS-SGMRKQQAHESSRPLSIERPGAVHPWVSAQLRNSVQPSHLFIQDPTMPPNPAPNPLTQLEEARRRLEEEEKRANKLPSKQR------------------------------------TKSQRKAGGGSAPPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAILPVFEEKIIGKVEKVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35625-1", "uniprot_id": "AXIN1_MOUSE", "id": "O35625-1", "name": "Axin-1", "aln": "--MNVQEQG--FPLDLGASFTEDAPRPPVPGEEGELVSTDSRPVNHSFCSGKGTSIKSETSTATPRRSDLDLGYEPEGSASPTPPYLRWAESLHSLLDDQDGISLFRTFLKQEG--CADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCVMKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGMSGYLPTLNEDEEWKCDQDADEDDGRDPLPPSRLTQKLLLETAAPRAPSSRRYNEGRELRYGSWREPVNPYYVNSGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESIQVNGRVPLPHIPRTYRMPKEIRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGEMPSGP-MASHKLPSVPAWHHFPPRYVDMGCSG--LRDAHEENP-ESILDEHVQRVMRTPGCQSPGPG-----HRSPDSGHVAKT-AVLGGTASGHGKHVPKLGLKLDTAGLHHHRHVHHHVHHNSARPKEQMEAEVARRVQSSFSWGPETHGH-AKPRSYSENAGTTLSAGD-LAFGGKTSAPSKRNTKKAESGKNANAEVPSTTEDAEKNQKIMQWIIEGEKEISRHRKAGHGS-SGLRKQQAHESSRPLSIERPGAVHPWVSAQLRNSVQPSHLFIQDPTMPPNPAPNPLTQLEEARRRLEEEEKRANKLPSKQRYVQAVMQRGRTCVRPACAPVLSVVPAVSDLELSETETKSQRKAGGGSAPPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15169-1", "uniprot_id": "AXIN1_HUMAN", "id": "O15169-1", "name": "Axin-1", "aln": "--MNIQEQG--FPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEG--CADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAG--LRDAHEENP-ESILDEHVQRVLRTPGRQSPGPG-----HRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGS-SGTRKPQPHENSRPLSLE-----HPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57094-1", "uniprot_id": "AXIN1_DANRE", "id": "P57094-1", "name": "Axin-1", "aln": "MSMSVNEKGICYLPDLGSSFTEDAPRPPVPGEEGDLVSSDGRQYNHSFYSSKSDSLKNEASIATPRRPDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGIHLFRTFLKQEE--CADMLDFWFACSGFRKQEANDGNE-KMLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCVTKLHIDPAMFDQAQTEIQTMMEENTYPLFLKSDIYLEYTRTGGESPKLFSDQSSVSGNGKVLPGYLPTVIEDVEWRCDQEEEQIAESDPTPSNRLTQKLPLETVPQRVANSKRYQDNREYRHASWREPVNPYYVNSGYALAPATSANDSEQQSMSSDADTLSLTDSSVDGVPPYRYRKPHRREIHESAKVNGRVPLPHIPRTNRIPKDIHVEPEKFAAELISRLEGVLREREAQEKLEERLKRVRLEEEGDDADISTGPSLANHRVPPAVHVQHYGGRYSEMSYNGLQLRDAHEENP-ESILDEHVQRVMKTPGCQSPGTGRHSPKSRSPDGLPAGKIPGLMMPLSGGQGKHQARQGPKGEAAHLHHHKHIHHTHYAAAGKPKEQAEAEAAR-MHGGFAWNTEQHHYGPKSRNYADGMSVGPNTMDPMGYSSKGSTLSKRPVRKGEDGRNFEMREPLPADDMERNQKILQWMMEGEKEAGRYKRGPYGSISGPKKAQGHEPARPSSVERLGAVHPWVTAQLRNNVQPSHPFIQDPTMPPNPAPNPLTQLEEARRRLEEERRKSGTLQAKQR------------------------------------HKNMKKQ------PCENITVAYYFRGEPIPYRTSVKGRIVTLGQFKELLTKKGSYKYYFKKVSYEFDCGVVFEEVREDDAILPIFEEKIIGKVEKVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V407-1", "uniprot_id": "AXN_DROME", "id": "Q9V407-1", "name": "Axin", "aln": "--MSGHPSG----IRKHDDNECSGPRPPVPGEESRVKKMTEG--------------------------------VADTSKNSSPSYLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHLNFYFACEGLKQQTD----PEKIKQIIGAIYR-FLRKSQLSISDDLRAQIKAIKTN--PEIPLSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQERCTSSG---ATGSGSAGSSGSGGSSLAGACALPPTTASGKQQLPQLVPPGAFINLPVSSVSGPPAGTCSASGSVYGPSTSASSSGSISATDTLPRSSTLPTLHEDSVLSLCDDFEKVQMQEGGGS---LGSGSVGAGARAPDYPIRLTRDLLIATQKRRLEIRPPG---AHGYVYNPSTTNTSYVPNSRVDSERASVSSGGRTDSDTMSISSCSMDGRPYIQRRHSSTESKAIRQSAMANKETNTFQVIPRTQRLHSNEHRPLKEEELVSLLIP------KLEEVKRKRDLEERARERNPGAALLTNERSSASDRAFAEAIREKFALDEDNDQDILDQHVSRVWKDQTPHRSPGTMSPCPPIPSRRRTATHDSGMVSDGAMSLSGHSMKHSKSMPDHSSCSRKLTNKWPSMNTDSGISMFSADTVTKYKDASSRSGSSTASKLEEAKRRLEDEPRRSRRYAQPPMQHLSQQPLASFSSSSSGGSISLPHQPPPLPAKPP-----------------------------------------------------------------------------ETIVVFSFCEEPVPYRIKIPGTQPTLRQFKDYLPRRGHFRFFFKTHCEDPDSPVIQEEIVNDSDILPLFGDKAMGLVKPSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : .* . ..*********. : . .: * ..:*.**.**.:*: **:*:**: **:.::::* * *:*:*** *::: * :: ***: :: ..: :* : :. *:: .. : :.* :** * .:: :.:* ** ** *::*: * : . . : :... ..*. .* : .. * : * . : ... . . :.. .. .. :.: :*. ::: .::*: * .* :. .: . .* . . .: . *:. : * : ::: * : . . . .:.:::.. * . :. . .. : : . . ::.: * . *..: :* :: * : : . * . . . : * . :. . :* :.. : : . .* : . : . :. ..: .* :.. .:. . * * . : : : :. .* .. . :: .* *. * . . ..* *. * ** ..:* . *.: * **:*** : * ** ***: *.::* ::::**. . : *. *: **: :*. :**:* :* :* *: *", "identical_positions": 114, "similar_positions": 240, "identity": "12.93%" }, { "cls_id": "homologset.agr.RGD:62086", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6SKG1-1", "uniprot_id": "ACSM3_RAT", "id": "Q6SKG1-1", "name": "Acyl-coenzyme A synthetase ACSM3, mitochondrial", "aln": "------MAMLLRARCFHRLAIPDPRRILYKDYRTAIPQNFSNYESMKHDFKIEIPEYFNFAKDVLDQWTNTEKTGKRLSNPAFWWVDGNGKEVRWSFEELGSLSRKFANILTEACSLQRGDRVMVILPKIPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKSKCIITDDTLAPAVDIVAAKCENLHSKLIVSQHSREGWGNLKEMMKYASDSHTCVDTKHNELMAIYFTSGTTGPPKMIGHTHSSFGLGLSVNGRFWLDLIASDVMWNTSDTGWAKSAWSSVFSPWTQGACVFAHYLPRFDSTSILQTLSKFPITVFCSAPTAYRMLIQNDITSYKFNSLKHCVSAGEPINPEVMEQWKKKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFNVEILDENGTILPPGQEGDIAVQVLPDRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDEDGYFWFVARSDDVILSSGYRIGPFEVESALIEHPSIAESAVVSSPDPIRGEVVKAFIVLNPDYKLHDQEQLKKEIQEHVKKTTAPYKYPRKIEFIEELPKTVSGKVKRNELRRKEWTTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UNX5-1", "uniprot_id": "ACSM3_MOUSE", "id": "Q3UNX5-1", "name": "Acyl-coenzyme A synthetase ACSM3, mitochondrial", "aln": "------MVMLLRARCFQRLAIPDPMRVLYKDYRTATPQNFSNYESMKQDFKIEIPEYFNFAKDVLDQWTNMEKAGKRLSNPAFWWIDGNGEELRWSFEELGLLSRKFANILTEACSLQRGDRVMVILPKIPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKAKCIITDDTLAPAVDAVAAKCENLHSKLIVSQHSREGWGNLKEMMKYASDSHTCVDTKHDEMMAIYFTSGTTGPPKMIGHTHSSFGLGLSVNGRFWLDLIASDVMWNTSDTGWAKSAWSSVFSPWTQGACVFAHYLPRFESTSILQTLSKFPITVFCSAPTAYRMLVQNDMSSYKFNSLKHCVSAGEPINPEVMEQWRKKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKILDENGATLPPGQEGDIALQVLPERPFGLFTHYVDNPSKTASTLRGSFYITGDRGYMDEDGYFWFVARSDDIILSSGYRIGPFEVESALIEHPSIAESAVVSSPDPIRGEVVKAFIVLNPDYKSHDQEQLKKEIQEHVKKTTAPYKYPRKVEFIEELPKTVSGKVKRNELRKKEWVTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53FZ2-1", "uniprot_id": "ACSM3_HUMAN", "id": "Q53FZ2-1", "name": "Acyl-coenzyme A synthetase ACSM3, mitochondrial", "aln": "MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWFVARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWKTI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :*:**:**** .. * *:** *** ***********:***: ****************: **:**: *******:: **:*:******** *********:***********::***::*************************************::****:*.****** **:************::**********:**:********.***:*:***:*****:* *** .******************** .************************ ******:*:****:.*********:**********.****:***::****:************.*:* *:*::***************************************:*:*:* ** *********.:****:**********************.***********:*********:**:**************.** ****:********************:******* ****** *******************:***:*****:***.******:*** * ", "identical_positions": 484, "similar_positions": 69, "identity": "82.59%" }, { "cls_id": "homologset.agr.RGD:620860", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUW3-1", "uniprot_id": "A0A0G2JUW3_RAT", "id": "A0A0G2JUW3-1", "name": "", "aln": "MGVIPGCCEVPEQSFMPLVIHLSNSLRHFQLKINLVFTEAQRLREERASLTRCQNLPVPSPTSGVPCPLSRGCRRGAMSCLLNNMVPVGLALL-VCGVQAFFLPNTMSLERLLSKYQHT-EPHS-------RVRRAIPMSDRQEILMLHNKLRGQVYP------PASNMEYMTWDEELERSAAAWAQRCLWEHGPASLLVSIGQNLAVHWGRYRSPGFHVQSWYDEVKDYTYPYPHECNPWCPERCSGAMCTHYTQMVWATTNKIGCAVHTCRSMSVWGDIWENAVYLVCNYSPKGNWIGEAPYKHGRPCSECPSSYGGGCRNNLCYREEHYHQ-KPEVDEMNEVESPPAPEETHVWVQPRVVKPSK-------TKKTPVVNFMTQVVHCDTKMKDSCKGSTCNRYQCPAGCLNNKAKVFGSLFYESSSSICRAAIHYGVIDDRGGLVDVTRNGMVPFFVKSQKNGLESLSKYKPSSSFTVSKVKETAVDCHTTVAQLCPFEKPATHCPRVRCPSRCGEEPSYWAPVYGTNIYADTSSICKAAVHAGVIVDEVGGYADVMPVDKKKSYVGSLRNGVQSESPSTPQNGNAFRIFPVRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZQ2-1", "uniprot_id": "CRLD2_MOUSE", "id": "Q8BZQ2-1", "name": "Cysteine-rich secretory protein LCCL domain-containing 2", "aln": "-----------------------------------------------------------------------------MSCLLNNMVLMGLALL-VCGVQAFFLPNTTSLEKLLSKYQHA-EPHS-------RVRRAIPMSDRQEILMLHNKLRGQVYP------PASNMEHMTWDEELERSAAAWAHRCLWEHGPAGLLRSIGQNLAVHWGRYRSPGFHVQSWYDEVKDYTYPYPHECTPRCRERCSGPMCTHYTQMVWATTNKIGCAVHTCRNMNVWGDTWENAVYLVCNYSPKGNWIGEAPYKHGRPCSECPSSYGGGCLNNLCHRAEKPHKHKPEVDMMNEVESPPAPEETHVWVQPRVIK----------TKKTPVINFMTQVVHCDTKMKDSCKGSTCNRYQCPAGCLSNKAKVFGSLFYESSSSICRAAIHYGVIDDRGGLVDVTRNGMVPFFVKSQKNGMESLSKYKPSSSFTVSKVTETAVDCHATVAQLCPFEKPATHCPRIQCPARCGEEPSYWAPVYGTNIYADTSSICKAAVHAGVIVDEVGGYADVMPVDKKKSYVGSLRNGVQSESLNTPQNGNAFRIFAVRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0B8-1", "uniprot_id": "CRLD2_HUMAN", "id": "Q9H0B8-1", "name": "Cysteine-rich secretory protein LCCL domain-containing 2", "aln": "-----------------------------------------------------------------------------MSCVLGGVIPLGLLFL-VCGSQGYLLPNVTLLEELLSKYQHN-ESHS-------RVRRAIPREDKEEILMLHNKLRGQVQP------QASNMEYMTWDDELEKSAAAWASQCIWEHGPTSLLVSIGQNLGAHWGRYRSPGFHVQSWYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETYTP-KPETDEMNEVETAPIPEENHVWLQPRVMRPTK-------PKKTSAVNYMTQVVRCDTKMKDRCKGSTCNRYQCPAGCLNHKAKIFGTLFYESSSSICRAAIHYGILDDKGGLVDITRNGKVPFFVKSERHGVQSLSKYKPSSSFMVSKVKVQDLDCYTTVAQLCPFEKPATHCPRIHCPAHCKDEPSYWAPVFGTNIYADTSSICKTAVHAGVISNESGGDVDVMPVDKKKTYVGSLRNGVQSESLGTPRDGKAFRIFAVRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RM30-1", "uniprot_id": "A0A8M1RM30_DANRE", "id": "A0A8M1RM30-1", "name": "", "aln": "---------------------------------------------------------------------------------MHALVSIALLFLGVSLAASLFLPDSLELRQLMQRYQEELEPNSTKPDAPVRTRRAIEWSDREEILKLHNKLRGEVYP------TASNMEYMIWDDELERSATSWAEQCQWEHGPQDLLMSIGQNLAVHWGRYRSPAYHVQAWYDEVKDYTYPYPHECNPWCPERCSGPMCTHYTQLVWATTNRVGCAVHVCPRMNVWGEIWENAVYLVCNYSPKGNWIGEAPYQHGRPCSQCPPSYGGVCRDNLCYKRDSERQETPEMNEVEKPQEPLQPRTTPPKPQPKPSSPKKPANAKPSSPKTTRNTYLAQNIKCETKMRDKCKGATCNRYNCPANCLNKQGKVWGTLYYDVQSSICRAAIHYGVIDNNGGLVDVTRKDSFPFFVKATKNGVESFSKYKAGNAFMVSNVQEQTIDCYATVAEICPFKSTTSHCPRVFCPANCINEPSYWAPVVGSNIYADGSSICRAAIHAGVIK-ASGGYVDLLALDKRKTYTGTLKNGIQSES-KTNREGGSFRVFAVRE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8INR8-1", "uniprot_id": "Q8INR8_DROME", "id": "Q8INR8-1", "name": "SCP domain-containing protein", "aln": "--------------------------------------------------------------------------------MLLIRSLVIVFLVAISEFDRNFAINHDNAGIVLREINKR------------RDRHGVPKLTLDNVLSKGCQSYAWKLS------KSATLNYS---DPTNKDYTESICRFEVKRG--------------------ALSRCVKNWYNGRK---------------FDILDPKAKDFTAMIWRSSVSLGYGDANINALQG---------VFVVRYTP-------------------PGNVKGLYTDNVPPRKRKQKK-----------------------------------------------------KKRENKQKEDCASRQDNRYVLLLSILSLVSTNWQS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PBI0-1", "uniprot_id": "M9PBI0_DROME", "id": "M9PBI0-1", "name": "SCP domain-containing protein", "aln": "-----------------------------------------------------------------------------------MSIKIILFLIAIEVCNQTIGIGLR--SLILEAHNRR------------RAKYGNQPMVLDEELCTECSEYADEIVRNEGVYTENYLEYLYATDPISAKHLQVVCVFREALP----------------------RECVRIWFHYRG----------------FAENTKYYRFTAMIWNASTRLGVGLGRIQETRY----------LVVRYAP-------------------PGNILREMASNVPKR---------------------------------------------------------------PTTFWDAEHIVDHGFEFA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: : : . :: :. * : . :: * . . ::: : . . *: *:. .. :* ::* :: :* . :* .*:* * . .*: : . . : : ", "identical_positions": 12, "similar_positions": 46, "identity": "2.01%" }, { "cls_id": "homologset.agr.RGD:620861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23514-1", "uniprot_id": "COPB_RAT", "id": "P23514-1", "name": "Coatomer subunit beta", "aln": "-MTAAENVCYTLINVPM-DSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFENLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLVELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDSNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEVRRSLGEIPIVESEIKKEAG--ELKPE-----------------EEITVGPVQKLVTEMGTYATQSALSSSRPTK-----KEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSLPKKPITDDDVDRISLCLKVLS-----ECSPLMNDIFNKECRQSLSQMLSAKLEEEKLSQKKESEKRNVTVQP--DDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLA--SKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEFRQMWAEFEWENKVTVNTNVTDLNDYLQHILKSTNMKCLTPEKALSG-YCGFMAANLYARSIFGEDALANVSIEKPVHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIF7-1", "uniprot_id": "COPB_MOUSE", "id": "Q9JIF7-1", "name": "Coatomer subunit beta", "aln": "-MTAAENVCYTLINVPM-DSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLVELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDSNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEVRRSLGEIPIVESEIKKEAG--ELKPE-----------------EEITVGPVQKLVTEMGTYATQSALSSSRPTK-----KEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSLPKKPITDDDVDRISLCLKVLS-----ECSPLMNDIFNKECRQSLSQMLSAKLEEEKLSQKKESEKRNVTVQP--DDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLA--SKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEFRQMWAEFEWENKVTVNTNMTDLNDYLQHILKSTNMKCLTPEKALSG-YCGFMAANLYARSIFGEDALANVSIEKPVHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53618-1", "uniprot_id": "COPB_HUMAN", "id": "P53618-1", "name": "Coatomer subunit beta", "aln": "-MTAAENVCYTLINVPM-DSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIRRSLGEIPIVESEIKKEAG--ELKPE-----------------EEITVGPVQKLVTEMGTYATQSALSSSRPTK-----KEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSLPKKPITDDDVDRISLCLKVLS-----ECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEKRNVTVQP--DDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLA--SKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEFRQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSG-YCGFMAANLYARSIFGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66HV4-1", "uniprot_id": "COPB_DANRE", "id": "Q66HV4-1", "name": "Coatomer subunit beta", "aln": "-MTAAENVCYTLINVTN-DSEPPSEVSLKTDLEKGEIKAKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGKLLQEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKESELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVHTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIELKEHPTHERVLQDLVMDILRVLTTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVTEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDTNEAAAADVLEFVREAIQRFDNLRPLIIEKMLEVFHAIKTVKIYRGALWILGEYCSTKEDIQSVMTEVRRSLGEIPIVENELKKEAG--EVKPE-----------------EEVTAAPAPKLVTEMGTYVTQSALSTSRPSK-----KEEDRPPLRGFLMDGDFYVAASLATTLTKVALRYVALAEDKRRQNSFVAEAMLIMATVLHLGKSSLPKKPITDDDVDRISLCLKVLS-----ECSPLMNDIFNKECRRSLSHMLAVRLEEEKLSQKKESEKRNVTVQA--DDPISFMQLTAKNEMASKEDQFQLSLLAAMGNTQRKEATDPLA--SKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPASCTDAEFRQMWAEFEWENKVTVNTNITDLNDYLLHILKSTNMKCLTPEKALSG-ICGFMAANLYARSIFGEDALANVSIEKPIHLGVDAPVNGHIRIRAKSQGMALSLGDKINLSQKRTAS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P45437-1", "uniprot_id": "COPB_DROME", "id": "P45437-1", "name": "Coatomer subunit beta", "aln": "--MTSQVPCYTIINSP--DLEVTNEMQLKRDLEKGDTNVKIETLKRVIKLLLNGERYPGLIMTIIRFVLPVQNHTIKKLLLIFWEIVPKTSADGKLLQEMILVCDAYRKDLQHPNEFLRGSTLRFLCKLKEPELLEPLMPAIRACLDHRHSYVRRNAVLAIFTIYKNFDWLVPDGPELIASFLDTQQDMSCKRNAFLMLLHADQERALNYLASCIDQVHTFGDILQLVIVELIYKVCHANPAERSRFIRCIYNLLNSS-SNAVRYESAGTLITLSLAPTAIKAAASCYIELVVKESDNNVKLIVLDRLVAMKEHEGMEKVMQDLVMDVLRVLAAPDIEVRRKTLALALDLVYSRNIGEMVLVLKKEVAKTHNV-EHEDTGKYRQLLVRTLHTCSIKFPDVAANVIPVLVEFLSDTNELAAADVLIFIREAIQKFPALRALIIEHLIEAFPQIKSSKIHRAAVWILGEYVEGSQ-ILEVIAVIQQTLGEVPMVEAEQRRLAG--DQTEEQKQQQGSAGGNAAGSAAEGSGSGNASNKVTSDGTYATQSAYS-LAPVA-----KAEKRPPLRQYLMDGDFFIGAALSATLTKLALRYAELETEARAQNRLTTQVMLIMSSILHLGKSGFPSKPITNDDTDRIFVCLRTLS-----ERTPEAISVFTLYCREALGKMLDAQHDEDQR-MLKEKQKATAKVQP--DDPVLFAQLSNGRDNQLGENVFESSLNQALAGSKNAQLSDVASPNSKLNKVTQLTGFSDPVYAEAYVNVNQYDIVLDVLIVNQTNDTLQNCTLELATLGDLKLVERPHPVVLAPHDFCNIKANVKVSSTENGIIFGNIVYET---ALNTNVVVLNTIHIDIMDYIIPASCTDTEFRQMWQDFEWENKVTVNTSFTDLHEYLKHLLKSTNMKCLTPEKALSG-QCGFMAANMYAKSIFGENALANLSIEKPVD-DPDSKVTGHIRIRAKSQGMALSLGDKISSSQKQSVQAA----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41810-1", "uniprot_id": "COPB_YEAST", "id": "P41810-1", "name": "Coatomer subunit beta", "aln": "MTSLSSQPAYTLVFDPSPSMETYSSTDFQKALEKGSDEQKIDTMKSILVTMLEGNPMPELLMHIIRFVMPSKNKELKKLLYFYWEIVPKLAEDGKLRHEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLREAELLEQMVPSVLACLEYRHAYVRKYAILAVFSIFKVSEHLLPDAKEIINSFIVAETDPICKRNAFIGLAELDRENALHYLENNIADIENLDPLLQAVFVQFIRQDANRTPALKAQYIELLMELLSTTTSDEVIFETALALTVLSANPNVLVPAVNKLIDLAVKVSDNNIKLIVLDRIQDINAN--NVGALEELTLDILRVLNAEDLDVRSKALDISMDLATSRNAEDVVQLLKKELQTTVNNPDQDKAMQYRQLLIKTIRTVAVNFVEMAASVVSLLLDFIGDLNSVAASGIIAFIKEVIEKYPQLRANILENMVQTLDKVRSAKAYRGALWIMGEYAEGESEIQHCWKHIRNSVGEVPILQSEIKKLTQNQEHTEENE---------------VDATAKPTGPVILPDGTYATESAFDVKTSQKSVTDEERDSRPPIRRFVLSGDFYTAAILANTIIKLVLKFENVSKNKTVINALKAEALLILVSIVRVGQSSLVEKKIDEDSLERVMTSISILLDEVNPEEKKEEVKLLEVAFLDTTKSSFKRQIEIAKKNKHKRALKDSCKNIEPIDTPISFRQFAGVDSTNVQKDSIEEDLQLAMKGDAIHATSSSSI--SKLKKIVPLCGFSDPVYAEACITNNQFDVVLDVLLVNQTKETLKNLHVQFATLGDLKIIDTPQKTNVIPHGFHKFTVTVKVSSADTGVIFGNIIYDG-AHGEDARYVILNDVHVDIMDYIKPATADDEHFRTMWNAFEWENKISVKSQLPTLHAYLRELVKGTNMGILTPSESLGEDDCRFLSCNLYAKSSFGEDALANLCIEKDSK---TNDVIGYVRIRSKGQGLALSLGDRVALIAKKTNKLALTHV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .**:: . . * .. .:: ****. : * :::* :: :*:*: * *:* *****:* ::: :**** .:****** : **:* :******:* ::*******::**.***** **:*.**** ::*:: ***::**:***: *:**:::*:: : *:**. *:* .*: : * ******: * . *::.**.** . * ::..:. :** *:*::* : .: .*: ::::*. : :**.:: * * :*:* :* .** *..: .*.. *:* :* ****:*******: :: : .:::*.:*:**** : *::** *:* :::**. *** ::* :****: .* * :::.: :*****::*::: ::.* ::**.*:.:*::*:.* *. **:.:: *::*.*::: ** *:*::::.: ::: * :*.*:**:*** . .. * ::.::**:*::: * :: : : . * . : ***.*:** . . : :.***:* :::.***: .* *: *: *:.*:: : : * : ::.:*:: :::::*:*.: .* * :*. :*: .: * * . .:: : : : : : *. * . . * *: * *:: . :: :: .* *: . :. ***:*:. * ********** : **:*:*****:****.:**:* :::*******::: * : **.* ::...***:*::.*:*****:*: . : . *:*. :*:****** **:. * .** ** ******::*::.. *: ** .::*.*** ***.::*. * *::.*:**:* ***:****:.*** . * *::***:*.**:******:: *:: ", "identical_positions": 339, "similar_positions": 341, "identity": "34.04%" }, { "cls_id": "homologset.agr.RGD:620862", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VCK7-1", "uniprot_id": "SYCN_MOUSE", "id": "Q8VCK7-1", "name": "Syncollin", "aln": "MSLLCPLLLALALVAVPGAHGNCPVPADLKKSDGTRTCARLYEKSDPYYDNCCQGPVLSVEPGTDLPYLPSGWSNTASSLVVGQRCEITVWSLPGKHGKTRKFTAGSYPRLEEYRKGIFGDWSDSISALYCKCY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35775-1", "uniprot_id": "SYCN_RAT", "id": "O35775-1", "name": "Syncollin", "aln": "MSPLCLLLLALALVAVPGARGACPVPADLKKSDGTRTCARLYENSDPYYDNCCQGPELSVDPGTDLPYLPSDWSNSASSLVVAQRCELTVWSLPGKRGKTRKFSTGSYPRLEEYRKGIFGTWAKSISGLYCKCY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VAF6-1", "uniprot_id": "SYCN_HUMAN", "id": "Q0VAF6-1", "name": "Syncollin", "aln": "MSPLRPLLLALALASVPCAQGACPASADLKHSDGTRTCAKLYDKSDPYYENCCGGAELSLESGADLPYLPSNWANTASSLVVAPRCELTVWSRQGKAGKTHKFSAGTYPRLEEYRRGILGDWSNAISALYCRCS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *******.:** *:* **..****:********:**::*****:*** *. **::.*:*******.*:*:******. ***:**** ** ***:**::*:********:**:* *:.:**.***:* ", "identical_positions": 90, "similar_positions": 31, "identity": "67.16%" }, { "cls_id": "homologset.agr.RGD:620863", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJP6-1", "uniprot_id": "P63_RAT", "id": "Q9JJP6-1", "name": "Tumor protein 63", "aln": "MNFETSRCATLQYCPDPYIQRFIETP-SHFSWKESYYRSAMSQS--TQTSEFLSPEVFQHIWDFLEQ----PICSVQPIDLNFVDEPSENGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNGMDQQIQNGSSSTSPYNTDHAQNSVTAP-------------SPYAQPSSTFDALSPSPAIPSN------TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDP----ITGRQSVLVPYEPP----QVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSAKNGDGTKRPFRQN-THGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSMQSQSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTMPEGMG-------------ANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVSFLARLGCSSCLDYFTTQGLTTIYQIEHYSMDDLASLKIPEQFRHAIWKGILDHRQLHDFSSPPHLLRTPSGASTVSVGSSETRGERVIDAVRFTLRQTISFPPRDEWNDFNFDMD--SRRNKQQRIKEEGE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88898-1", "uniprot_id": "P63_MOUSE", "id": "O88898-1", "name": "Tumor protein 63", "aln": "MNFETSRCATLQYCPDPYIQRFIETP-AHFSWKESYYRSAMSQS--TQTSEFLSPEVFQHIWDFLEQ----PICSVQPIELNFVDEPSENGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAP-------------SPYAQPSSTFDALSPSPAIPSN------TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDP----ITGRQSVLVPYEPP----QVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSAKNGDGTKRPFRQN-THGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSMQSQSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTMPEGMG-------------ANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVSFLARLGCSSCLDYFTTQGLTTIYQIEHYSMDDLASLKIPEQFRHAIWKGILDHRQLHDFSSPPHLLRTPSGASTVSVGSSETRGERVIDAVRFTLRQTISFPPRDEWNDFNFDMD--SRRNKQQRIKEEGE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3D4-1", "uniprot_id": "P63_HUMAN", "id": "Q9H3D4-1", "name": "Tumor protein 63", "aln": "MNFETSRCATLQYCPDPYIQRFVETP-AHFSWKESYYRSTMSQS--TQTNEFLSPEVFQHIWDFLEQ----PICSVQPIDLNFVDEPSEDGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAP-------------SPYAQPSSTFDALSPSPAIPSN------TDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDP----ITGRQSVLVPYEPP----QVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQN-THGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMG-------------ANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVSFLARLGCSSCLDYFTTQGLTTIYQIEHYSMDDLASLKIPEQFRHAIWKGILDHRQLHEFSSPSHLLRTPSSASTVSVGSSETRGERVIDAVRFTLRQTISFPPRDEWNDFNFDMD--ARRNKQQRIKEEGE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JQ56-1", "uniprot_id": "A0AC58JQ56_DANRE", "id": "A0AC58JQ56-1", "name": "Tumor protein 63 (p63)", "aln": "---MTSPYAAVQFCPERAFQRLREPAAACLSWAEGSFLASMSQGQGSQGTDILGQDVLNQLLEMLDQS---ALHSMQPIELNFSEGSSVGSASNTIQISMDCITMHGP--EEPLTPQYTSLGLLNSMDQ--NGGSTSTSPYNNDHAQNNVTAP-------------SPYAQPSSTFEALSPSPAIPSN------TDYAGPHTFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVLTNPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNDGQIAPPSHLIRVEGNSHAQYVEDS----ITGRQSVLVPYEPP----QVGTEFTTILYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQHVTDGTKSSEGTKRPFRQASSHLSQLNSIKKRRSTDEEVFCLPIKGREIYEILVKIKESLELMQFLPQQTIESYRQQQQ----NLLQKQSSLPPQPAFGSSSPTLGK----NKLPSVSQLINPQQRNALTPSGMPGGLTDSLLQSQPFPLPSVTPPMMGGPVPMNTDLSSLSPNNPLQSQLQMVPSSHCTPPPPYPMDNSISSFLLRLGCSACLDYFTAQGLTNIYQIENYNLEDLSRLKIPTEFQHIIWKGIMEYRQTMEFSPPPHILRTSSGTSTVSVGSTEARGERVIDAVRFTLRQTISFPPRDDWTDFSFDLAPDSRRNKQQRIKEEGE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMZ4-1", "uniprot_id": "Q8IMZ4_DROME", "id": "Q8IMZ4-1", "name": "", "aln": "MSLHKSASFSLTFNQNTSIVSRSNSRTIFEAFKEFLDFWDIGNEVSAESAVRVSSNGAFNLPQSFGNESNEYAHLATPVDPAYGGNNTNNMMQFTNNLEILANNNSDGNNKINACNKFVCHKGTDSEDDSTEVDIKEDIPKTVEVSGSELTTEPMAFLQGLNSGNLMQFSQQSVLREMMLQDIQIQANTLPKLENHNIGGYCFSMVLDEP---PKSLWMYSIPLNKLYIRMNKAFNVDVQFKSKMPIQPLN-LRVFLCFSNDVSAPVVRCQNHLSVEPLTANNAKMRESLLRSE-NPNSVYCGNAQGKGISERFSVVVPLNMSRSVTRSGLTRQTLAFKFVCQNSCIG---RKETSLVFCLEKACGDIVGQHVIHVKICTCPKRDRIQDER-----------------------------QLNSKKRKSVPEAAEEDEPSKVR----------------RCIAIKTEDTESNDSRDCDDSAAEWNVSRTPDGDYRLAITCPNKE---WLLQSIEGMIKEAAAEVLR------------------------------------NPNQENLRRHANKLLSLKKRAYELP-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :: : : : :. :: * :.: :: :. : :: : : : *:: : : . . ::.: . . . ::. :. *: : . .. * . : : ..:*: ::* * : : . * :* .. * : *.: :::. .: * ** *:*** :: *: ::::. : * .: . ::.*: * ** ** . :. .: . *:* * *.:: * :. *: * **:** : . : * *: ::*:*:.**:* *: ::. **. *:::*:: :..:**:** *** ** *:.* *:: .: * : * : :. :* :: ::.: : : * . : : . .* * *:. :*: :.* : . . . *.: :: * ", "identical_positions": 73, "similar_positions": 164, "identity": "10.0%" }, { "cls_id": "homologset.agr.RGD:620864", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1Q2-1", "uniprot_id": "CCNL1_RAT", "id": "Q9R1Q2-1", "name": "Cyclin-L1", "aln": "----------------------------MASGPHPTST-----AAAASASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSVIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLN-LDGTPALSTLGGFSPASKPSSPREVKAEEKSPVSINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRE-DLKSSNRHGHKRKKSRSRSQSKTRD--HSDVTKKHRHER---GHHRDRRERSRSFERSH-KGKHHGGSRSGHG--RHRR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q52KE7-1", "uniprot_id": "CCNL1_MOUSE", "id": "Q52KE7-1", "name": "Cyclin-L1", "aln": "----------------------------MASGPHPTSTAAAAAAAAASASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLN-LDGTPALSTLGGFSPASKPSSPREVKAEEKSPVSINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRTSRSASRSRSRTRSRSRSHSPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRE-DLKSSNRHGHKRKKSRSRSQSKTRD--HSDVTKKHRHER---GHHRDRRERSRSFERSH-KGKHHGGSRSGHG--RHRR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK58-1", "uniprot_id": "CCNL1_HUMAN", "id": "Q9UK58-1", "name": "Cyclin-L1", "aln": "----------------------------MASGPHSTAT------AAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLN-PDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRD-DLKSSNRHGHKRKKSRSRSQSKSRD--HSDAAKKHRHER---GHHRDRRERSRSFERSH-KSKHHGGSRSGHG--RHRR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVX0-1", "uniprot_id": "CCNL1_DANRE", "id": "Q7ZVX0-1", "name": "Cyclin-L1", "aln": "------------------------------------------------------MSLGMLSPHLNTPPPNNQGILIGDKVYSEVFLAIDNSIIPEDRLSTTPSMLDGLDHETETDLRILGCERIQSAGILLRLPQVAMATGQVIFQRFFFSKSFVKHNFEIVAMACVNLASKIEESPRRVRDVINVFHHLKQGKGKKS-TPLILDQNYINTKNQVIKAERRILKELGFCVHVKHPHKIIVMYLQVLECEKNQMLVQTAWNYMNDALRTSAFVRFEPETIACACIYLAARVLQIPLPSKPHWFLLFGATKEDIKEICINTMKLYSREKPHSEQLERQVEKRKIFLEEARLKARGQN-PNGTPALASINGFSPASKPSSPRDVKMDDKSPNSK-----LKEPENRQLFAKSPLNGSIK--KEDGKVFQNGKNHSRSRSRSTSRSPHRH---RRSHSGTYSSHS-----SHSPSPRQKARRPSPISQLRTDRD-RPSETSRHSNKRRRSRSRSRSNSRERVRDRDHIKHKQERSGSGHHWDHRDRERDRSRDHGRNKRQSRSHSGHSHSRHRR-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W526-1", "uniprot_id": "Q9W526_DROME", "id": "Q9W526-1", "name": "Cyclin-L1", "aln": "MATRGAGSTVVHTTVTALTVETITNVLTTVTSFHSNSVNISNNNSSSGAAPGADAAGGDAGGVAAAQADANKPIYP--RLFNRIVLTLENSLIPEGKIDVTPSSQDGLDHETEKDLRILGCELIQTAGILLRLPQVAMATGQVLFQRFFYSKSFVRHNMETVAMSCVCLASKIEEAPRRIRDVINVFHHIKQVRAQKEISPMVLDPYYTNLKMQVIKAERRVLKELGFCVHVKHPHKLIVMYLQVLQYEKHEKLMQLSWNFMNDSLRTDVFMRYTPEAIACACIYLSARKLNIPLPNSPPWFGIFRVPMADITDICYRVMELYMRSKPVVEKLEAAVDELKKRYIDARNKTKEANTPPAVITVDRNNGSHNAWGGFIQRAIPLPLPSEKSPQKDSRSRSRSRTRTHSRTPRSRSPR-SRSPSRERTKKTHRSRS-SRSRSRSPPKH----KKKSRHYSRSPTRSNSPHSKHRKSKSSRERSEYYSKKDRSGNPGSSNNLGDGDKYRNSVSNSGKHSRYSSSSSRRNSGGG---GDGRSGGGGGGGGGGNGNHGSRGGHKHRDGDRSRDRKR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : . . * :::..: *::::*:*** ::. *** **** :*.******** **:*****************:*:***:*****:*.:* ***:*: *******:***:*********::* :.:: :*::** * * * ********:***************:********: *::: *:* :**:***:***..*:*: **:********:** *:****. * ** :* .. :* :** ..:.** *.** * ** *:: * :*: *:: * .. :: .* * * : * * :. . : :::* . : : :**: *** *::* :* :.:* ** . .** : : : . : *. .:.. .. : .* *.* .:. . :: *. . . . :..: . .: . . *.*: ", "identical_positions": 190, "similar_positions": 137, "identity": "33.27%" }, { "cls_id": "homologset.agr.RGD:620865", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09056-1", "uniprot_id": "LIF_MOUSE", "id": "P09056-1", "name": "Leukemia inhibitory factor", "aln": "MKVLAAGIVPLLLLVLHWKHGAGSPLPITPVNATCAIRHPCHGNLMNQIKNQLAQLNGSANALFISYYTAQGEPFPNNVEKLCAPNMTDFPSFHGNGTEKTKLVELYRMVAYLSASLTNITRDQKVLNPTAVSLQVKLNATIDVMRGLLSNVLCRLCNKYRVGHVDVPPVPDHSDKEAFQRKKLGCQLLGTYKQVISVVVQAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17777-1", "uniprot_id": "LIF_RAT", "id": "P17777-1", "name": "Leukemia inhibitory factor", "aln": "MKVLAAGIVP-LLLILHWKHGAGSPLPITPVNATCAIRHPCHGNLMNQIKSQLAQLNGSANALFISYYTAQGEPFPNNVDKLCAPNMTDFPPFHANGTEKTKLVELYRMVTYLGASLTNITWDQKNLNPTAVSLQIKLNATTDVMRGLLSSVLCRLCNKYHVGHVDVPCVPDNSSKEAFQRKKLGCQLLGTYKQVISVLAQAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15018-1", "uniprot_id": "LIF_HUMAN", "id": "P15018-1", "name": "Leukemia inhibitory factor", "aln": "MKVLAAGVVP-LLLVLHWKHGAGSPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKKLGCQLLGKYKQIIAVLAQAF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******:** ***:***************************.******:.************** ************::***.**:****.**.*****:*******:*.**.:** *** *** ***:*:**: ***** *::*****.******.**:******. ** *.*:.**:*********.***:*:*:.***", "identical_positions": 159, "similar_positions": 34, "identity": "78.33%" }, { "cls_id": "homologset.agr.RGD:620866", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63645-1", "uniprot_id": "PAR2_RAT", "id": "Q63645-1", "name": "Proteinase-activated receptor 2", "aln": "MRSLSLAWLLGGITLLAASASCNRTVN-APGPN-SKGRSLIGRLDTPPPITGKGAPVEPGFSVDEFSASVLTGKLTTVFLPVIYIIVFVIGLPSNGMALWVFFFRTKKKHPAVIYMANLALADLLSVIWFPLKISYHLHGNDWTYGDALCKVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSRKRANIAVGVSLAIWLLIFLVTIPLYVMRQTIYIPALNITTCHDVLPEEVLVGDMFSYFLSLAIGVFLFPALLTASAYVLMIKTLRSSAMDEHSEKKRRRAIRLIITVLSMYFICFAPSNVLLVVHYFLIKSQRQSHVYALYLVALCLSTLNSCIDPFVYYFVSKDFRDQARNALLCRSVRTVKRMQISLTSNKFSRKSSSYSSSSTSVKTSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55086-1", "uniprot_id": "PAR2_MOUSE", "id": "P55086-1", "name": "Proteinase-activated receptor 2", "aln": "MRSLSLAWLLGGITLLAASVSCSRTENLAPGRNNSKGRSLIGRLETQPPITGKGVPVEPGFSIDEFSASILTGKLTTVFLPVVYIIVFVIGLPSNGMALWIFLFRTKKKHPAVIYMANLALADLLSVIWFPLKISYHLHGNNWVYGEALCKVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHPRKKANIAVGVSLAIWLLIFLVTIPLYVMKQTIYIPALNITTCHDVLPEEVLVGDMFNYFLSLAIGVFLFPALLTASAYVLMIKTLRSSAMDEHSEKKRQRAIRLIITVLAMYFICFAPSNLLLVVHYFLIKTQRQSHVYALYLVALCLSTLNSCIDPFVYYFVSKDFRDHARNALLCRSVRTVNRMQISLSSNKFSRKSGSYSSSSTSVKTSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55085-1", "uniprot_id": "PAR2_HUMAN", "id": "P55085-1", "name": "Proteinase-activated receptor 2", "aln": "MRSPSAAWLLGAAILLAASLSCSGTIQ-GTNRS-SKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** * *****. ***** **. * : ... . ********::: . :****..**. **:******:***********::* ****:**********:*:*******************************:**:***:* **:***:**********************************.**:****:*:********:********::***:***************::******.**************:**********: ********:*****:***:**:***:**:***:***:**********:* ********:*********************:****:*:***********::**:**:*:*.****.*******:*****", "identical_positions": 320, "similar_positions": 61, "identity": "80.2%" }, { "cls_id": "homologset.agr.RGD:620867", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12273-1", "uniprot_id": "PIP_HUMAN", "id": "P12273-1", "name": "Prolactin-inducible protein", "aln": "MRLLQLLFRASPATLLLVLCLQLGANKAQDNTRKIIIKNFDIPKSVRPNDEVTAVLAVQTELKECMVVKTYLISSIPLQG-AFNYKYTACLCDDNPKTFYWDFYTNRTVQIAAVVDVIRELGICPDDAAVIPIKNNRFYTIEILKVE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99N82-1", "uniprot_id": "Q99N82_RAT", "id": "Q99N82-1", "name": "Prolactin-inducible protein homolog", "aln": "MASLQILYQPQAVIHVLILCLILEIASGQDNRNTLLSLNLEVSSINKAN-EFTVTLTVTNKVDKCMVVKISTEDNPNIKYLSAKATYTACICTIHN--FFWDIHVSANTVLQGKAEVVPDKDICPDGENIFPVTSYVETVTSKILVMP", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **:*::.... :*:*** * ..*** ..:: *:::.. :.* *.*..*:* .::.:***** .. :: : : .****:* : *:**::.. .. : . .:*: : .****. ::*:.. . . : * ", "identical_positions": 38, "similar_positions": 63, "identity": "25.68%" }, { "cls_id": "homologset.agr.RGD:620868", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R519-1", "uniprot_id": "ACMSD_MOUSE", "id": "Q8R519-1", "name": "2-amino-3-carboxymuconate-6-semialdehyde decarboxylase", "aln": "MKIDIHTHILPKEWPDLEKRFGYGGWVQLQQQGKGEAKMIKDGKLFRVIQQNCWDPEVRIREMNQKGVTVQALSTVPVMFSYWAKPKDTLELCQFLNNDLAATVARYPRRFVGLGTLPMQAPELAVEEMERCVKALGFPGIQIGSHINTWDLNDPELFPIYAAAERLNCSLFVHPWDMQMDGRMAKYWLPWLVGMPSETTMAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTIGRIAHGFNMRPDLCAQDNPSDPRKYLGSFYTDSLVHDPLSLKLLTDVIGKDKVMLGTDYPFPLGEQEPGKLIESMAEFDEETKDKLTAGNALAFLGLERKLFE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R5M5-1", "uniprot_id": "ACMSD_RAT", "id": "Q8R5M5-1", "name": "2-amino-3-carboxymuconate-6-semialdehyde decarboxylase", "aln": "MKIDIHTHILPKEWPDLEKRFGYGGWVQLQQQGKGEAKMMKDGKVFRVIQQNCWDPEVRIREMNQKGVTVQALSTVPVMFSYWAKPKDTLELCQFLNNDLAATVARYPRRFVGLGTLPMQAPGLAVEEMERCVKELGFPGIQIGSHINMWDLNDPELFPIYTAAERLNCSLFVHPWDMQMDGRMAKYWLPWLVGMPSETTTAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTIGRIAHGFNMRPDLCARDNSSDPRKYLGSFYTDSLVHDPLSLKLLTDVIGKDRVILGTDYPFPLGEQEPGKLIESMADFDEETKDKLTAGNALTFLGLERKLFE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TDX5-1", "uniprot_id": "ACMSD_HUMAN", "id": "Q8TDX5-1", "name": "2-amino-3-carboxymuconate-6-semialdehyde decarboxylase", "aln": "MKIDIHSHILPKEWPDLKKRFGYGGWVQLQHHSKGEAKLLKDGKVFRVVRENCWDPEVRIREMDQKGVTVQALSTVPVMFSYWAKPEDTLNLCQLLNNDLASTVVSYPRRFVGLGTLPMQAPELAVKEMERCVKELGFPGVQIGTHVNEWDLNAQELFPVYAAAERLKCSLFVHPWDMQMDGRMAKYWLPWLVGMPAETTIAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTVGRISHGFSMRPDLCAQDNPMNPKKYLGSFYTDALVHDPLSLKLLTDVIGKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGNALAFLGLERKQFE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:**********:************::.*****::****:***:::************:**********************:***:***:******:**. **************** ***:******* *****:***:*:* **** ****:*:*****:****************************:*** *******************************:***:***.*******:**. :*:*********:******************:*:*********** ********* :******:**.*****:******* **", "identical_positions": 286, "similar_positions": 39, "identity": "85.12%" }, { "cls_id": "homologset.agr.RGD:620869", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99N75-1", "uniprot_id": "Q99N75_MOUSE", "id": "Q99N75-1", "name": "Prolactin-induced protein", "aln": "MASLQMFYQPGALMHLLILCLFLETPYGQENWNNPLSLDMIVSP-MKGKNEFTVTLQVKNNVGQCMVVKVSTVMNPSIKYLSAHAIYTSCLCSAN--KYFWDIQVSDNTALQGKAEVVPAKSICPDDEKIFPVTSYVETATQKIIVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99N74-1", "uniprot_id": "Q99N74_RAT", "id": "Q99N74-1", "name": "Prolactin-induced protein", "aln": "MASLQMFYQPRAAMHLLILCLFLETAYGQDIWSNPLSLELIVSP-LKKANEFTVTLQVKNNVDQCMAVKVSTVSNPNIKYISSHAIYTSCLCDVN--NYFWDIQVIANTALQGKAEVVPAKDICPNDENIFPVTSYIGTATQKIFVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12273-1", "uniprot_id": "PIP_HUMAN", "id": "P12273-1", "name": "Prolactin-inducible protein", "aln": "MRLLQLLFRASPATLLLVLCLQLGANKAQDNTRKIIIKNFDIPKSVRPNDEVTAVLAVQTELKECMVVKTYLISSIPLQG-AFNYKYTACLCDDNPKTFYWDFYTNRTVQIAAVVDVIRELGICPDDAAVIPIKNNRFYTIEILKVE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **::::. . **:*** * : .*: : : :: :. :: :*.*..* *:.:: :**.**. : . :: : : **:***. * .::**: . .. : . .:*: .***:* ::*:.. : : : *.", "identical_positions": 33, "similar_positions": 60, "identity": "22.45%" }, { "cls_id": "homologset.agr.RGD:62087", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61532-1", "uniprot_id": "MK06_MOUSE", "id": "Q61532-1", "name": "Mitogen-activated protein kinase 6", "aln": "------------------MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ-GPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLAR-----IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILDSIPVVHEEDRQELLSVIPVYIRNDMTEP---HRPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPTDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPIHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTSYSAEPCWQYPDHHENKYCDLECSHTCNYKTRSSPYLDNLVWRESEVNHYYEPKLIIDLSNWKEQ-SKEKSDKRGKSKCERNGLVKAQIALEEASQQLA--ERERGQ--------GFDFDSFIAGTIQLSAQHQSADVVDKLNDLNSSVSQLELKS---LISKSVSREKQEKGRANLAQLGALYQSSWDSQFVSGGEECFLISQFCCEVRKDEHAEKENT--YTSYLDKFFSRKEDSEMLETEPVEEGKRGERGREAGLLSGGGEFLLSKQLESIGTPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHKTYSSILKHLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27704-1", "uniprot_id": "MK06_RAT", "id": "P27704-1", "name": "Mitogen-activated protein kinase 6", "aln": "------------------MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ-GPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLAR-----IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRQELLSVIPVYIRNDMTEP---HKPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPTDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPIHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTSYSAEPCWQYPDHHENKYCDLECSHTCNYKTRSPSYLDNLVWRESEVNHYYEPKLIIDLSNWKEQ-SKDKSDKRGKSKCERNGLVKAQIALEEASQQLA--ERERGQ--------GFDFDAFIAGTVQLSAQRESADVVDKLNDLNSSVSQLEMKS---LISKSVSREKQEKGRANLAQLGALYQPSWESQFVSGGEECFLISQFCCEVRKDEHVEKENT--YTSYLDKFFSRKEDSEMLETEPVEEGKRGERGREAGLLSSGGEFLLSRQLESIGTPQFHSPGGSPLKSIQATLTPSAMKSSPQIPHKTYSNILKHLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16659-1", "uniprot_id": "MK06_HUMAN", "id": "Q16659-1", "name": "Mitogen-activated protein kinase 6", "aln": "------------------MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ-GPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLAR-----IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRQELLSVIPVYIRNDMTEP---HKPLTQLLPGISREALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDCQFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTNYSTEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWKEQ-SKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQ--------GFDFDSFIAGTIQLSSQHEPTDVVDKLNDLNSSVSQLELKS---LISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSGGEDCFFINQFC-EVRKDEQVEKENT--YTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEGFLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA57WKX4-1", "uniprot_id": "A0AA57WKX4_DANRE", "id": "A0AA57WKX4-1", "name": "Mitogen-activated protein kinase 6", "aln": "------------------MAEKFESLMNIHGFDLGPRYMDLKPLGYGGNGLVFSAVDTDCDKRVAVKKIVLTDPQSVKHALREIKIIRRLDHDNIVKVFETLGPSGRRLTEDVSSLTEVNSVYIVQEYMETDLCKVLEQ-GLLSEDHARLFMYQLLRGLKYIHSANVLHRDLKPANLFVNTEDLVLKIGDFGLAR-----IMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRLELQSVIPVFIKNDMSEP---HTPLAKLLPGVSPEALDFLEKILTFNPMDRLTAEEALAHPYMSDYSFPLDEPVSLHPFHIEDEVDDILLMDESHSQVYNWDRYHESQFSDQDWHLHSTHELEDVQRDPRALSDVTDEEEVQIDPRKYMDGDCEKFLEDPSFD--LPPEHLWQLEDHHENKYCDQECSYTCNYKAVSPSYLDNLIWRDSEVNHYYEPKLIIDLSNWKEQQSKEKIDKKGKSKCEKNGLVKAQIALKEASQNHTVPEKDRDQEKHQNHNQGFDFDSFIASTIKLSLQPESGD-VDLLNELNTSVSQLDTRAPCGSMSKSISQEKEEKCLVNLAQLGVRAPCPWESFTDCGVAESSLIDQACWDVRKDEQLQKENSSCQSSYLDRLFSKRDDVEPEILEPVEVVS----TTESDFISCSGEIVFNMQLESLAIPGFEGAADIPLKSIQATLAPSAVKHSPQIAHKTYSSIFKHLN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41808-1", "uniprot_id": "SMK1_YEAST", "id": "P41808-1", "name": "Sporulation-specific mitogen-activated protein kinase SMK1", "aln": "MNCTLTDNTRAINVASNLGAPQQRTIFAKERISIPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISN-----IFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNG-CLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQGPFDFTYESELNSMSKLRDYLVEEVKNFKTDLSSSSL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .::: . :.: * :: ** *. * * *. .. . . : ::: :** : * : . ::::.*: : :: : : :.:* ** :: **.:*:.. * * * : *:**:* ********:*:******.*:: . :. *** ****** ::. * : : *::: :.*:***:*.**** : *:*::*:**.***:**: : *.:* * ..:.*: *:. : . .:: :: :: . : :: .:* : * ::::* * **::::*.:* :.. .**..*:*::**::. * ***:. : . .:: *.: :. : : : .. ::*. . ", "identical_positions": 96, "similar_positions": 146, "identity": "12.58%" }, { "cls_id": "homologset.agr.RGD:620870", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BKC6-1", "uniprot_id": "HBAP1_RAT", "id": "Q5BKC6-1", "name": "HSPB1-associated protein 1", "aln": "MEAGCEGSSPQTLGERTMGEEGERVKPFTPEKAKEVIMSLQQPAIFCNMVFDWPSRHWTAKHLSKVLEGKQIRFRMGLRSTGTVPQFETECSYVDATLEEFLAWNCDQSR-ISGPFKKYDHSKFWAYADYKYFVTLFEDKTDVFQEVMWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFQKA--RRHMVTLSPGQVLFVPRHWWHYVESLDPVTVSINSWIELEEDHLARVEEAVTRMLVCTLKTAEDPHHPRTWLNPTEVEETSHEVNSCYLNSAVCAFFDHCERAKEVEMQAPRANGEEPGVQ-----EHMEVEQARDPSSDVGAGKQEAASPFGPDLVPVTPASEE----RGGALEGDSQECTSRNGEHCAELPCARRQQASKGA--RAEAGQSAPRYPVAPSRVFVSTDDLLDCLVNPQVTRMVAQLLIQG-KSL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BK58-1", "uniprot_id": "HBAP1_MOUSE", "id": "Q8BK58-1", "name": "HSPB1-associated protein 1", "aln": "MAAGCEGIAPPTLGERTVGEEGEPVKPFTPEKAKEIIMSLQQPAIFCNMVFDWPSRHWTAKHLSKVLEGKQIRFRMGLRGTGTVPQYETECSYVDATLEEFLTWNCDQSS-ISGPFKDYEHSKFWAYADYKYFVTLFEDKTDVFQEVVWSDFGFPGRNGQESTLWIGSFGAHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKCFPQFQKA--RRHMVTLSPGQVLFVPRHWWHYVESLDPVTVSINSWIELEEDHLARVEEAITRMLVCTLKTAEDPHHPRTWLNPTEVEETSHEVNSCYLNSAVCAFFDHCEKAKAVELQVLSANGAEPRVQE----EHMEVEQAQGPSLTSRAEKQEAVSLFGPDLIPVTPASEE----RGGALEGDSEESVSSNGGHFAELPCARRQQTSKGA--SALTEPLAPRGPMAHSRVFVSTDDLLDCLVNPQVTRMVAQLLIQG-KSCDTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EW2-1", "uniprot_id": "HBAP1_HUMAN", "id": "Q96EW2-1", "name": "HSPB1-associated protein 1", "aln": "MAAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNAKYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSS-ISGPFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKA--QRHAVTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRMLVCALKTAENPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDGEHMKKEELNVCNHMEVGQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFGSDGKDFVDKDGEHFGKLHCAKRQQIMSNS--ENAIEEQIASNTTTTPQTFISTDDLLDCLVNPQVTRIVAQLLIQG-RSL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AXL5-1", "uniprot_id": "HBAP1_DANRE", "id": "Q6AXL5-1", "name": "HSPB1-associated protein 1 homolog", "aln": "MSS----------------------KPFTPEEARRIVQVLQKPAVFLNMTTDWPALHWTVEHLSACLT-KRIRFRVGKRSEDMAPLFETECSYVEATIKEFLSWTANDGEPLVGPFLDYHCKEFWAYADYKYIAQLFQDKPAMFQDVVWSDFGFPGRDGRDSTLWIGTQCANTPCHLDSYGCNLVFQIQGRKRWHLFPPDDTACLYPTRVPYEESSVFSHVNVIRPDLKKFPAYGRA--RLYTVTLQPGQVLFVPRHWWHYVESVDPVTVSVNSWIEMDMDDEARVAEALTKTIVCAVKSSPSLDNSDQWLNPTEDGVSSHDENMQYLNLAVKVCMN--KKRDDIEDQPK----------------AEAVKRDFSGVLKSPASPPSLVS-FGPHLIPVHLTEKP---QCSSTKDSCCFSCTDSPQCQITTKDQDKLRSDNKLGQRSGQSVLQDTENPGGSGEMHISTNDVLECLVHPDVIALVTRLIMCRQRELHS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VB06-1", "uniprot_id": "Q9VB06_DROME", "id": "Q9VB06-1", "name": "", "aln": "--------------------------MELSSKLRDLILNTHVPLVLEQFPLKWECFEGSLHDWCKRFD-KEATCLPAFELMALADSSTPQWERKRTKSSQLLNMQQFLRK---YGVLDGDSTHWAAYQYKKADEVPLSCR----SGIGFSSFGFP-DIGNDYRFWLGSEQANTPCHYDTFGVNIVVQVHGCKSWLLFPPETP--LQSTRIPYEETSVYCLENFYAPDPAKISSYEHLGRQAYHCNLQPGNVLIVPRHWWHYVEAKS-TSLSVNYWVPLKVDMDLILDEFLVMHIVESFVRGESNQVKQYLLNPNQLDNVSTKP--------------------------------------------SDLFAQFEQAVQNLESGKSTRQLYDTDYISQADWKTL-------------LNSINLSVRPLEVMPHEEYKLLLNAN----SKRFRVAANPPETTPISSNCELLVSSMCAPRVIAEMKREFFRRLGKSNSL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..: : :: : * :: :: .* . . . . . : *. . . . . . :. .::* . . . ..: ** * :. : . : :*.**** *.: :*:*: *:**** *::* *:*.*::* * * ****: . * .**:****:**:. *. ** :. : : : : .*.**:**:**********: . .::*:* *: :. * : * :. :* :. . . . ***.: * : . . :... :. . . . . : . . . . : ::..: * * : : :: . ", "identical_positions": 71, "similar_positions": 121, "identity": "14.29%" }, { "cls_id": "homologset.agr.RGD:620871", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08675-1", "uniprot_id": "PAR3_MOUSE", "id": "O08675-1", "name": "Proteinase-activated receptor 3", "aln": "--MKILILVAAGLLFLPVTVCQSGIN-VSDNSAKPTLTIKSFNGGPQNTFEEFPLSDIEGWTGATTTIKAECPEDSISTLHVNNATIGYLRSSLSTQVIPAIYILLFVVGVPANIVTLWKLSLRTKSISLVIFHTNLAIADLLFCVTLPFKIAYHLNGNNWVFGEVTCRITTVVFYGNMYCAILILTCMGINRYLATAHPFTYQKLPKRSFSMLMCGMVWVMVFLYMLPFVILKQEYHLVHSEITTCHDVVDACESPSSFRFYYFVSLAFFGFLIPFVIIIFCYTTLIHKLKSKDRIWLGYIKAVLLILVIFTICFAPTNIILVIHHANYYYHNTDSLYFMYLIALCLGSLNSCLDPFLYFVMSKVVDQLNP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q920E1-1", "uniprot_id": "PAR3_RAT", "id": "Q920E1-1", "name": "Proteinase-activated receptor 3", "aln": "MEMKVLILVGVRLLFLPTTVCQSGMKHVSDNSA---LTAESFNGN-EHSFEEFPLSDIEGWTGATTTIKAKCPEESITTLHVNNATMGYLRSSLSTKVIPAIYILVFVIGVPANIVTLWKLSSRTKSICLVIFHTNLAIADLLFCVTLPFKIAYHLNGNDWVFGEVMCRVTTVAFYGNMYCAILILTCMGINRYLATVHPFTYRKLPKRNFTLLMCGVVWVMVVLYMLPLAILKQEYHLVQPGITTCHDVHDTCESPLPFQFYYFVSLAFFGFLIPFVVSVFCYTTLIHKLNAQDRKWLRYIKAVLLILVIFTICFAPTNIILIIHHANYYYSNTDSLYFMYLIALCLGSLNSCLDPFLYFIMSKIVDQLTS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00254-1", "uniprot_id": "PAR3_HUMAN", "id": "O00254-1", "name": "Proteinase-activated receptor 3", "aln": "--MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** **:... **:* *.****:: ::* * *. ::*.* ::*****:* :******* *:* :***:* : ***:***:*** *****::*****:*:**:***** **** * **:**. .:*:*******:*****************:****** ** *** *******:**:*:*:.****** .*****: ***:.:::: **:**. *.*****: ******:**:. ******* ::***. .*::***:************: ::**:::*:.*:: *: ** *:** *************:****:******** ***.***:********************:*** :: .. ", "identical_positions": 241, "similar_positions": 84, "identity": "64.1%" }, { "cls_id": "homologset.agr.RGD:620872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88634-1", "uniprot_id": "PAR4_MOUSE", "id": "O88634-1", "name": "Proteinase-activated receptor 4", "aln": "-MCWPLLYPLVLGLSISLAEGIQTPSIYDDVESTRGSHEGPLGPTVELKEPKSSDKPNPRGYPGKFCANDSDTLELPASSQALLLGWVPTRLVPALYGLVVAVGLPANGLALWVLATRVPRLPSTILLMNLAVADLLLALVLPPRLAYHLRGQRWPFGEAACRVATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGQRLTTGLCLVAWLSAATLALPLTLHRQTFRLAGSDRMLCHDALPLTEQTSHWRPAFICLAVLGCFVPLLAMGLCYGATLRALAANGQRYSHALRLTALVLFSAVASFTPSNVLLVLHYSNPSPEAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSHEFREKVRA-MLCRQPEASSSSQASREAGSRGTAICSSTLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q920E0-1", "uniprot_id": "PAR4_RAT", "id": "Q920E0-1", "name": "Proteinase-activated receptor 4", "aln": "-MCWPLLYPLMLGFSISPAE-CQTPSIYDDVESTREGQEASLRPTVELNESKSPDKPNPRGFPGKPCANNSDTLELPASSEALLLGWVPTRLVPAIYGLVVVVGLPANGLALWVLATRVPRLPSTILLMNLAVADLLLALVLPPRLVYHLRGQRWPFGEAACRVATAALYGHMYGSVLLLAAVSLDRYLALVHSLRARALRGQRLTTILCLVAWLSAATLVLPLTFHRQTFLLAGSDRMLCHDALPLAEQTSHWRPAFICLAVLGCFVPLLAMVLCYGATLRALAANGQRYSHAVRLTALVLFSAVAAFTPSNVLLVLHYSNPSPEAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSHEFREKVRA-MLCRQLKASSSSQASREAGSRGTAICSSTLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96RI0-1", "uniprot_id": "PAR4_HUMAN", "id": "Q96RI0-1", "name": "Proteinase-activated receptor 4", "aln": "MWGRLLLWPLVLGFSLSGGT--QTPSVYDESGSTGGG-----------DDSTPSILPAPRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLAAADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASHWQPAFTCLALLGCFLPLLAMLLCYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSSLLQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:**:**:*:* . ****:**: ** . .:.... * ***:**: ***:******* **.**************:****:.***************:.******:******.*******.****:.****************:*****************************.********:**: **:.*** **:*.****::**** ** ***:******** *:***:*** ***:****:***** *******::***.*:**.**:****:** **** *.***:**:****:***.******************************* ***:**** :: *. : :*:** *.**** . ** * ", "identical_positions": 281, "similar_positions": 64, "identity": "70.6%" }, { "cls_id": "homologset.agr.RGD:620873", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQ14-1", "uniprot_id": "IL23A_MOUSE", "id": "Q9EQ14-1", "name": "Interleukin-23 subunit alpha", "aln": "MLDCRAVIMLWLLPWVTQGLAVPRSSSPDWAQCQQLSRNLCMLAWNAHAPAGHMNLLREEEDEETKNNVPRIQCEDGCDPQGLKDNSQFCLQRIRQGLAFYKHLLDSDIFKGEPALLPDSPMEQLHTSLLGLSQLLQPEDHPRETQQMPSLSSSQQWQRPLLRSKILRSLQAFLAIAARVFAHGAATLTEPLVPTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Z84-1", "uniprot_id": "IL23A_RAT", "id": "Q91Z84-1", "name": "Interleukin-23 subunit alpha", "aln": "MLDCRAIILLWLLPWATQGLAVPRSSSPDWAQCQQLSRNLCTLAWSAHTPVGQMDLLREEGEEETKSDVPRIQCGDGCDPQGLKDNSQFCLQRIRQGLVFYKHLLDSDIFTGEPSLLPDSPVDQLHTSLLGLSQLLQPEDHHWETQQMPRLSPSQQWQRSLLRSKILRSLQAFLAIAARVFAHGAATLTEPLVPTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NPF7-1", "uniprot_id": "IL23A_HUMAN", "id": "Q9NPF7-1", "name": "Interleukin-23 subunit alpha", "aln": "MLGSRAVMLLLLLPWTAQGRAVPGGSSPAWTQCQQLSQKLCTLAWSAHPLVGHMD-LREEGDEETTNDVPHIQCGDGCDPQGLRDNSQFCLQRIHQGLIFYEKLLGSDIFTGEPSLLPDSPVGQLHASLLGLSQLLQPEGHHWETQQIPSLSPSQPWQRLLLRFKILRSLQAFVAVAARVFAHGAATLSP------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..**:::* ****.:** *** .*** *:******::** ***.**. .*:*: **** :***..:**:*** ********:**********:*** **::**.****.***:******: ***:************.* ****:* **.** *** *** *********:*:************: ", "identical_positions": 136, "similar_positions": 36, "identity": "69.39%" }, { "cls_id": "homologset.agr.RGD:620874", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P36222-1", "uniprot_id": "CH3L1_HUMAN", "id": "P36222-1", "name": "Chitinase-3-like protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVKASQTGFVV---------------------------LVLLQCCSAYK-----------------------------------------------------------------------------------------------------LVCYYTSWSQYREGDGSCFPDALD--RFLCTHIIYSFANIS--NDHIDTWE-WNDVT------LYGMLNTLK--NRNPNLKTLLSVGGWNFGS--------QRFSKIASNTQSRRTFIKSVPPFLRTH-GFDGLDLAWLYP-------------------------------GRRDKQHFTTLIKEMKAEFIKEAQPGKK-QLLLSAALSAGKVTIDSSYDIAKISQHLDFISIMTYDFHGAWR--GTTGHHSP-----------LFRGQEDASPDRFSNTDYAVGYMLRLG--APASKLVMGIPTFGRSFTLAS----SETG----VGAPISGPGI-PGRFTKEAGTLAYYEICDFLRGATVHRILGQ--------------QVPYATKGNQ-------WVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGS-------FCGQDLRFPLTNAIKDALAAT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WTV1-1", "uniprot_id": "CH3L1_RAT", "id": "Q9WTV1-1", "name": "Chitinase-3-like protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLQLPGFAV---------------------------LMLLQSCSAYK-----------------------------------------------------------------------------------------------------LVCYYTNWSQYREGNGSCFPDALD--HSLCTHIIYSFANIS--NNKLSTSE-WNDVT------LYGMLNTLK--TRNPRLKTLLSVGGWSFGS--------ERFSRIVSNAKSRKTFVQSVAPFLRTY-GFDGLDLAWLYP-------------------------------GPKDKQHFTTLIKELKAEFTKEVQPGTE-KLLLSAAVSAGKVTLDSGYDVAQIAQHLDFINLMTYDFHGTWR--HTTGHHSP-----------LFRGQQDTGPDRFSNVDYGVGYMLRLG--APTNKLVMGIPTFGKSFTLAS----SENQ----VGAPITGSGL-PGRYTKEKGTLAYYEICDFLRGAEVHRILGQ--------------QVPFATKGNQ-------WVGYDDPESVKNKVKYLKNKQLAGAMVWAVDLDDFRGS-------FCGHNVHFPLTNAIKEALAVA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61362-1", "uniprot_id": "CH3L1_MOUSE", "id": "Q61362-1", "name": "Chitinase-3-like protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHTSTEAR--------------------------MGMRAALTGFAV---------------------------LMLLQSCSAYK-----------------------------------------------------------------------------------------------------LVCYFTSWSQYREGVGSFLPDAIQ--PFLCTHIIYSFANISS-DNMLSTWE-WNDES------NYDKLNKLK--TRNTNLKTLLSVGGWKFGE--------KRFSEIASNTERRTAFVRSVAPFLRSY-GFDGLDLAWLYP-------------------------------RLRDKQYFSTLIKELNAEFTKEVQPGRE-KLLLSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWR--QITGHHSP-----------LFQGQKDTRFDRYSNVNYAVQYMIRLG--AQASKLLMGIPTFGKSFTLAS----SENQ----LGAPISGEGL-PGRFTKEAGTLAYYEICDFLKGAEVHRLSNE--------------KVPFATKGNQ-------WVGYEDKESVKNKVGFLKEKKLAGAMVWALDLDDFQG--------TCQPKEFFPLTNAIKDALA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VZV2-1", "uniprot_id": "Q9VZV2_DROME", "id": "Q9VZV2-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFPPRLLRIAFVICLLIVLLSPSADSAQTKTRRRLRRPTTSVSSSRSNLIESKKSTEAPEAEKRIDQITSATTTSARRTR--------------------------LRSKAKLGAAAAG------------------GAAVAAGGTALVASGSSLKGKKTKVD-----------------------------------------------------------------------------------------DGTPKIVCYYTNWSQYRVKIGKFVPEDIP--ADLCTHIIFAFGWLK--KNKLSSYE-SNDETKDNVPGLYERMMTLK--KANPKLKILLALGGWSFGT--------QKFKDMSSTRYTRQTFVYSAIPFLRKR-GFDGLDMDWEYPK------------------------------GSDDKKNFVLLLKELREAFEAEAQELKKPRLLLSAAVPVGPDNIRGGYDVPAIASYLDFINLMAYDFHGKWE--RETGHNAP-----------LYAPSTDSEWRKQLSVDNAASLWVKMG--APKEKLVIGMPTYGRSFTLAN----PDKHG---PNAPASGGGR-EGVYTKEGGFLAYYEICEMLLNGAVYVWDDEM-------------KVPYLVDGDQ-------WVGFDDERAIRNKMHWIKSNGFGGAMVWTIDMDDFKGE-------VCGGNVKYPLIGAMREELLGISRGKEAK-----------DVNWTAVAATFEDIEEKPEPIKISVDEILNKVRKPQVQKKQRIKSGANAVASNTRPAQVFCYLTSWSAKRPGAGKFQPENIDPKLCTHIVYAFATLQDYKLTEATDDDPENYE---SVIALRDNNPDLQILLAIGGWAFGS-TPFKELTSNVFRMNQFVYEAIDFLRDYKFNGLDVDWEYPRGAEDRVAYVSLLKELRVAFEGEAKSSGLP--RLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERTVGHNSPLFALESATGYQKKLTVDYSAREWVKQGAPKEKLLIGMPTYGRSFELVNDTQFDIGSPSSGGGKAGKFTNEAGFLSYYEVCSFLAADNTTLVWDSEQQV-PFAYRGNQWVGFDDERSLKTKTEWLKEQGFGGIMVWSIDMDDFSGRCGSGKYPLLTALNDELKDY-----KVELEYDG--------------PYESHGPRGAYTTKDPHDVTCAEEDGHISYHKDWADCTHYYMCEGERKHHMPCPANLVFNPQENVCDWPENVEGCHTPTEAPA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2M5-1", "uniprot_id": "Q9W2M5_DROME", "id": "Q9W2M5-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGKLLALLAV---------------------------LCLSQVIGAER----------------------------------------------------------------------------------------------------IVNCYWGTWANYRSGNGKFDVSNID--AGLCTHLSYSFFGIND-NGEIQSLDTWLDYDLG----FINQAISLK--NQNSNLKVLAVVGGWNEGS--------TKYSSMSGDWYKRQNFINSALNLLRNH-GFDGLDLDWEYPNQRG--------------------------GNWNDRANFVTLLREIKEAFAPYG-------YELGIAVGAGESLASASYEIANIAQQVDFINVMTYDFAMASD--GQTGFNAP-----------QWA------------VENAINFWLSQG--APANKLVLGVGTYGRSFQLSD----SSQNW---PGAPCRGEGS-AGSYTGSTGYLGYNEICQNN-WHTVFDYDNA---------------APYAYSGDQ-------WVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRG--------QCGET--YPLLKTINRKLRW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5U2-1", "uniprot_id": "CHI10_DROME", "id": "Q9W5U2-1", "name": "Probable chitinase 10", "aln": "MHPYVPSVLVVVVLAISVKAHIRVDKLQIHSESNYKPAFIRSAVESIPLDIDAILLLRNSTKPEFGDAFLPLRSAVESIPKLYQSNTSRFRKNPDVRSFVRDSVESLPNDEDGLEHIEIFTKYYNSVSDVAGVDLKSKKLTHVNLDPGTISDKYAAFIARGNSEDYYPKSYRAGSPHQELLKMMNIEHTDKLDRYSDLQHQQSYGALGLANRNDLKMTKKVLCYMSNWAFYRSGEAHFVPEQIDPNLCSAIIYSFASLDPDHLTIREFDSWVDLDNQYYRRVTSLGVPVLIALGGWTDSSGSKYSRLVSDNLKRRVFISSVSSFLLRHGFSGLHLDWNYPKCWQSDCSRGPVTDRPNLTKLLRELRTEFQSVDPKFQLGVAISGYKEIIKEAYDFPALSDIVDYMTVMTYDYHGAWEQKTGHVSPLYGLSSDTYPQYNTNYTMQLLLKMGARREKLVLSIPFYGQSFTLATAHQILAGPGVAASGPGDAGELTKQPGMLAYYEICQRLTKFNWISDRNLNVIFGPFAMLNDQWVGYEDPTSAQAKARYAANNNFAGVAAWTIDLDDFRNLCCNESYPLLRAINRALGRLDSEPPTQPNCKRPTLLATPVPPQMTTISSDGSGGLGQNHDHTTSLPSGQISSSPVSTTITSTFPWWSSTTKRPREPTKTTAQPTHTTILIPAGINPVVQPSNCKSGEFFADSNNCNAYYHCFFAGELQQQFCPSGLHWNNEAKGCDWPSSAQCSLKLDQHLSTSYPNPIQTSKKPETTLKPNKKPSEISTHHQVNSTSSRPQYMRPTILECTEGDYYPHRNCRKYYICVNKALVPSECGGDLHWDGIKKLCDWPENVQCVTSKKYLKIIKSSSANEEDPCKGEKRVPYPGNCSKYLFCLWNRLQASDCPPGLHYNERIGNCDWPAAAKCNPKGSESSEEAELNAMPKPPTPQTPSSHLRPTYPTEKPVPKPRDSHYKVICYFTNWAWYRKGIGRFTPDDIN--TELCTHVIYGFAVLDYSELVLRTHDSWADVENN----FYTRVTSLK--SKG--IKVSLALGGWNDSQG-------DKYSRLVRSPMARSRFVRHALEFIEKY-GFEGLDLDWEYPVCWQTECN---------------------KGSTEEKDGFTAWVQELSEAFRPRG-------LMLSTAVSPSRKIIDAGYDIPQLSRYFDWIAVMTYDFHGHWD--KKTGHVAP-----------LYHHPDDD--FEYFNVNYSINYWMEKG--APSQKLVMGIPLYGQSFTLEN----TNSSG---LNAKAPAPGE-AGEFTRAAGFLAYYEICERVNRQGWQVVHDEFG-----------RMGPYAYKGTQ-------WVSYDSPDMVRKKSLLVRSLKLGGGMVWALDLDDFKN--------RCGNG-VHPLLTEIHNVLKDPPSLMEIPGPIETTPTEYPGMEEEIHESNGEGPEVQPIEAVMQTCENEGEEHEGILDPNHVLEEENIEATEMATEFKIICYFTNWAWYRQGGGKFLPEDIDSDLCTHIIYGFAVLSRDNLTIQPHDSWADLDNKFYERIVAYRKKGAKVTVAIGGWNDSAGDKYSRLVRNPEARSRFIRNVLDFIEEYNFDGLDLDWEYPVCWQVDCKKGTAEEKIGFSALVRELFYAFQPRGLILSAAVSPNKKVIDAGYEVAELSHYFSWISVMAYDYHGQWDKKTGHVAPMYSHPEGTAN---FNANFSMNYWISMGADRRKLVMGIPLYGQSFSLAETTKHQLNAPTYGGGEAGEATRARGFLAYYEICLKIRHHRWNVVRDTKGRIGPFAYHGDQWVSFDDVPMIRHKSEYIKAMGLGGAMIWALDLDDFKNVCECESYPLLKAINRVLRGFGGPQPKCLLENPKSTMKPNIKPPFRPTINAPSGPNLDSPTQNVSLNVLSIKCHSKNYLAHEWDCTKYYICEHGTYVERSCPLGLQWN--KTYCDWPTNVQSSLGSNQRTQEPAVHRPNPTSVITEPPIINNSYKVVCYFTSWAWYRSSQGKFVPEDIDANLCTHLIYGFAVLDSKSLTIKTHDSWTDIDNRFYERVVEYKQRGLRVMLAIGGWNDSLGSKYARLVLNSQSRRRFVASVISFLEQHGFEGLDLAWEFPVCWQVNCNRGNPTEKDGFVALVKELSEAFKENGLILSAAVSPSKMVIDAGYNVFELSPYFDWVAVMTYDFHGHWDMRTGQIAPLFHRGGDENLYLNGNFSIHYWLERGIPNDKLVMGMPMYGQTFTLADQNRRSLNDKTVGPGKAGTFTRADGFLAYYEICEKVVNDDWKVVRDEEGIFGSYAYSGNQWISYDDVTTIRRKSQFIKSLQLGGGMIWALDLDDFRGLCGCGKHPLLRTLSQELLGIPGQKAKDCI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W303-1", "uniprot_id": "IDGF4_DROME", "id": "Q9W303-1", "name": "Chitinase-like protein Idgf4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLYALFSLLVGS--------------------------LAIGQISAAGSH---------------------------------------------------------------------------------------------------HLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSSNKLVSNNEKLDLDLGS--SLFRQVTGLK--RKYPALKVLLSVGGDKDTVD---PENNKYLTLLES-SNARIPFINSAHSLVKTY-GFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTALVRELKNAFRPDG--------YILGLSVLPNVNSSLFFDVPAIINNLDYVNLHTYDFQTPERNNEVADFPAP-----------IYELNERN---PEFNVNYQVKYWTGNR--APAAKINVGIATYGRAWKLTK----DSGLTGLPPVAEADGVAP-AGTQTQIPGLLSWPEVCAKLPN-PANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRG--------GCTGHDKFPILRQVKSKL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8T0R7-1", "uniprot_id": "IDGF5_DROME", "id": "Q8T0R7-1", "name": "Chitinase-like protein Idgf5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMWIQKNPFLGLLLCSF-------------------------LAFFQSTYAEVG---------------------------------------------------------------------------------------------------KLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGIDAVTYKIKSLDPSLTNDR----QHYRHITALR--KKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQ-SEHRKSFQASVLAELNNN-GFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFS-SSSVDEKSEEHREQFATLLEELQSDLRRGG--------QLLTVSMLPHVSAELFIDVPKVLSNVDFVNLGTYDFQTPERDPKVADLPTP-----------LYAMYDRD---PSHNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNMTR----NSGITGYPPIPAANGAAP-PGRQTVTPGLLSWPEICDLLQQQPQDREVP----HLRKVGDPTKRFGIYAYRAADDQGENGLWVGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRG--------QCAG-EKFPILRSIKFKL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MLZ7-1", "uniprot_id": "IDGF3_DROME", "id": "Q8MLZ7-1", "name": "Chitinase-like protein Idgf3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTGSLWLSLALSL-------------------------AVLAQFKVSAAP---------------------------------------------------------------------------------------------------NLVCFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYAGVNADNYEMQSINKRLDLEQ----RHLAQITSMK--ERYPHIKFLLSVGGDADTYE-----GNQYIKLLESGQQGHRRFIESARDLVRRY-NFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETHKGQVTALIKDLSAALKQND--------LLLSLTVLPNVNSSWYYDAPSIAPSLDFINLGTFDFLTPQRNPEEADFSAP-----------TYEAVGQNR-LGHYNLNFQMEHWLLQR--VPANKINIGIATYGRSWKMSK----DSGDSGMPVVPSTQGPAP-AGPQSKQEGLLNWAEICSLMPN-PSNSNARGPNAPVKRVVDPTKRYGSYAFRAADENGDHGLWISYDDPDSASSKAMYARARNLGGVALFDLTQDDFRG--------QCTN-DRFPMLRAIKYRLL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W3V1-1", "uniprot_id": "Q9W3V1_DROME", "id": "Q9W3V1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNYEKLDGSSAGRITDELSRKEQRN-------------------------CSLRTLVCWSALLFSLLCLCLG--------------------FIGLGLLGIQTGEVHKVG-----------------------------------------------------------------------------------------------QRLVCYYAS-----DGTHNLSLLDVP--GDLCTHINIGPATLDNATIVLPDTLRQVLQN---------DTRSFR--AAHPQVHLLLWIGGADSGRS---------FALMVANHAMRKLFLRSLREILRTYPSLDGIDLDWEFPS-----------------------------AYDRERMHLSQLLYEIRTEWRREKRTN----DILSLAVAAPEGIAFYAYDIREINLYADYVNLMSYDFHFYREDTPFTGLNAP-----------LYARSQERSLMATFNINYTVQWWLKSG--LEPQRLVVGLPTYGHSFTLVN----PLNHR---IGAPASGYGK-CGQLGFTTLTETCECVTKFFKPNLSYDAES---------------CSPYLSALQE-------WISYENQTSIACKANYVKSLNLGGVMVFSLNTDDLKNSCSIMPNLKYSEKPVFPLTQAIKDILRESL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06350-1", "uniprot_id": "CHI2_YEAST", "id": "Q06350-1", "name": "Sporulation-specific chitinase 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVGHSAQHRSKSSLVSHLLILLIFITIIIEMCLYNKIFKNQRSDDIRDNFNNGGHRVPSNVQN---------------------HGTHIRDEAFISGVYYSN-------------------------WSPYKPRFHFPHDIN------------------------------------------------------------------------------------------------LKQVSHIYYAFFKINSRTGGIENTDSWSDLEMNLYKSLAIKNSELIKESSNNSVQNILPLG---CIGELFYLKNTCSDKKFKVIMSIGGWSDSEN---------FKIIIKDDKLLQNFVDSSVETMFRL-GFDGIDLDWEFPGNNE--------------------------SEPRGYLKLVRMLRLKLNSLESQIFGKRTEDHFQLSIAAPAFKDKLFYLPITEIDQYVDYWNMMTYDYYGSWS--ETTGYHSN-----------LFSETELNG-------NFAMHYMIDRFG-VNSRKLVLGMAAYGRSFHIKDNKFEPFNQNTVLINKIFKGVGKPTKEIDKADGKEGIWPYKNLPKIGTIEQYDPKY-------------VSAYCFDEKNS-----IFISYDNTKSVKTKAEYVTHNNLGGGFWWESCGEAYANE---------SRSLINAFNEGLHFNVSSKPSIFQDVRVKKYYLNKYGDGGFLSPYLKHLDSRKQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0A8M1P3P0-1", "uniprot_id": "A0A8M1P3P0_DANRE", "id": "A0A8M1P3P0-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHISRAFAFLCLV--------------------------VSVGAQRTQSR-----------------------------------------------------------------------------------------------------LSCYLDVLTPHTREGS-------------CTHIILPSVSSDDELYLQSLTENEYDAIQR-----------MK--ERNSALKILLGLEIKSSRLK-----------LMSANEASVGSFIQTLLTYLKEK-RLDGLDVIWLDG-------------------------------TPSDTELFTDFLKSIKGVFEEEMRP-----LLLSASVKEPTDKTVASYDEQILSQYVDFISILPAQLQTDGQYISKTAQHWQDKQVDLQKLGLVMPGFLQRSRHRHHHRNHPKHDDTTAEEGKKDHVHLLNLYLGDQVCQAVK----SGQLQFITLTSVSDEQSPIKEVLQQGFGGIGVVLIDLDVFGNSMCPNMTQKE--RATVESKAIMHSHHGHRRHGHGDHRHHHTGHHTRHHTRHHDRHHGRHHHGRHHHGHRPHHHGHRHHG-----RHHHHHHHHSTTTQSSVTQVTPKGME----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: .: : : * : ::*:*: . : : *: : . : : : :.: .: . . ... : . . ", "identical_positions": 4, "similar_positions": 35, "identity": "0.17%" }, { "cls_id": "homologset.agr.RGD:620875", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88829-1", "uniprot_id": "SIAT9_MOUSE", "id": "O88829-1", "name": "Lactosylceramide alpha-2,3-sialyltransferase", "aln": "MHTEAVGGAARRPQKLRSQAAAP-ACRAMPSEFTSAKLRSDCSRTSLQWYTRTQHKMRRPSLLIKDICKCTLVAFGVWLLYILILNYTAEECDMKRMHYVDPDRIKRAQSYAQEVLQKECRPRYAKTAMALLFEDRYSINLEPFVQKVPTASEAELKYDPPFGFRKFSSKVQSLLDMLPEHDFPEHLRAKACKRCVVVGNGGILHGLELGHALNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDVEYYANDLFVTVLFKSVDFKWLQAMVKNESLPFWVRLFFWKQVAEKVPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGHDKNIPTIGVIAVVLATHLCDEVSLAGFGYDLSQPRTPLHYFDSQCMGAMHWQVMHNVTTETKFLLKLLKEGVVEDLSGGIH---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68G12-1", "uniprot_id": "SIAT9_RAT", "id": "Q68G12-1", "name": "Lactosylceramide alpha-2,3-sialyltransferase", "aln": "----------------------------MPNEFTSAKLRSDCSRTSLQWYTQTQHKMRRPSLLLKDILKCMLVVFGVWLLYILKLNYTAEECDMKKLNYVDPARIKRAHRNTQEVFQKECRPGHAKKTMDLLFKGKYSMDLEPFVQKIPTASEAELKYDPPFGFRKFSSKVQSLLDMLPEHDFPEHLRAKHCKRCVVIGNGGILHGLELGHALNQFDVVIRLNSAPIEGYSEHVGNKTTIRMTYPEGAPLSDAEYYANDLFVAVLFKSVDFKWLQAMVKNESLPFWIRLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGHDKNIPTIGIIAIVLATHLCDEVSLAGFGYDLSQPRTPLHYFDSQCMGAMNWQVMHNVTTETQFLQKLIKEGVVQDLSGGIH---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UNP4-1", "uniprot_id": "SIAT9_HUMAN", "id": "Q9UNP4-1", "name": "Lactosylceramide alpha-2,3-sialyltransferase", "aln": "MRTKAAGCAERRPLQPRTEAAAAPAGRAMPSEYTYVKLRSDCSRPSLQWYTRAQSKMRRPSLLLKDILKCTLLVFGVWILYILKLNYTTEECDMKKMHYVDPDHVKRAQKYAQQVLQKECRPKFAKTSMALLFEHRYSVDLLPFVQKAPKDSEAESKYDPPFGFRKFSSKVQTLLELLPEHDLPEHLKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWKQVAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCDEVSLAGFGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETKFLLKLVKEGVVKDLSGGIDREF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.*:* .********.******::* ********:*** ** *:.****:**** ****:******:::**** ::***: :*:*:****** .**.:* ***: :**::* ***** *. **** ****************:**::*****:****:** *:****:*.***********:**************:************************* ***:*****:********:*******:*:****:***********:**********************************:***:****:**:*******************.**************.**::*.********:** **:*****:******. ", "identical_positions": 311, "similar_positions": 58, "identity": "74.4%" }, { "cls_id": "homologset.agr.RGD:620876", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55193-1", "uniprot_id": "CCR2_RAT", "id": "O55193-1", "name": "C-C chemokine receptor type 2", "aln": "MEDSNMLPQFIHGILSTSHSLFPRSIQELDEGATTPYDYDDGEPCHKTSVKQIGAWILPPLYSLVFIFGFVGNMLVIIILISCKKLKSMTDIYLFNLAISDLLFLLTLPFWAHYAANEWVFGNIMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVITSVVTWVVAVFASLPGIIFTKSEQEDDQHTCGPYFPTIWKNFQTIMRNILSLILPLLVMVICYSGILHTLFRCRNEKKRHRAVRLIFAIMIVYFLFWTPYNIVLFLTTFQEFLGMSNCVVDMHLDQAMQVTETLGMTHCCVNPIIYAFVGEKFRRYLSIFFRKHIA---KNLCKQCPVFYRETADRVSSTFTPSTGE-------QEVSVGL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51683-1", "uniprot_id": "CCR2_MOUSE", "id": "P51683-1", "name": "C-C chemokine receptor type 2", "aln": "MEDNNMLPQFIHGILSTSHSLFTRSIQELDEGATTPYDYDDGEPCHKTSVKQIGAWILPPLYSLVFIFGFVGNMLVIIILIGCKKLKSMTDIYLLNLAISDLLFLLTLPFWAHYAANEWVFGNIMCKVFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVITSVVTWVVAVFASLPGIIFTKSKQDDHHYTCGPYFTQLWKNFQTIMRNILSLILPLLVMVICYSGILHTLFRCRNEKKRHRAVRLIFAIMIVYFLFWTPYNIVLFLTTFQESLGMSNCVIDKHLDQAMQVTETLGMTHCCINPVIYAFVGEKFRRYLSIFFRKHIA---KRLCKQCPVFYRETADRVSSTFTPSTGE-------QEVSVGL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41597-1", "uniprot_id": "CCR2_HUMAN", "id": "P41597-1", "name": "C-C chemokine receptor type 2", "aln": "-------------MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTKCQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKGKSIGRAPEASLQDKEGA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :****:* * *. :* .* .** :*** * **** .****** :*******************::***.*****.:*****:**********:***:*** ********* ***:*******************************************:***:**:******:*******.:::* :.*****. *:**:*******.*:****:*********:**:*************:**:***************::*.**** :*:*** :**** ************:**:********** : * : :** * :* * :... .:. : . *: *.*: ", "identical_positions": 254, "similar_positions": 62, "identity": "65.63%" }, { "cls_id": "homologset.agr.RGD:620878", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86UU1-1", "uniprot_id": "PHLB1_HUMAN", "id": "Q86UU1-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "--------------------------------MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLEEGRTVIG-SAARDISLQGPGLAPEHCYIENLRG-TLTLYPCGN-ACTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTP----QTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPG-------AAGKKPAATSPLSPMANGG-RYLLSPPTSPGAMSVGSSYENTSPAFSPLSSP--ASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRP-----------SGARS-ESPRLSRKGGHERPPSPG--LRGLLTDSPAATVLAEARRATESPRLG-GQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSPSRQLVGRTFS---------------DGLAT-RTLQPPESPRLGRRGLD--SMRELPPLSPSLSRRALSPLPTR--------TTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPT--LGESLAPHKGSFSGRLSPAYSLGSLTGASPCQSPCVQRKLSSG--DLRVPVT--RERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAG---ASGRSSEEPGVATQRLWESMERSDEENLKEECSSTES---------------TQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKE-------------------------------------------AEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPK--------------------------------------------TTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRS-KMDGEATSPLPRTRS-----GPLPSSSGSSSSSSQLSVATLGRS------------------------PSPKSALLTQN------------------------------------------GTGS--------------LPRNLAATLQDIETKRQLALQQK---------------GQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGP--SGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PDH0-1", "uniprot_id": "PHLB1_MOUSE", "id": "Q6PDH0-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "--------------------------------MDPLNRSQLGPGCKTQAVVQKGPLDLIETGQGLKVQTDKPHLVSLGSGRLSTAITLLPLEEGRTVIG-SAARDISLQGPGLAPEHCYIENLRG-TLTLYPCGN-ACTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGVRAPGPTYNPGSAESESLVNGNHTA----QPATRAPSACASHSSLVSSIEKDLQEIMDSLVLEEPG-------AAGKKPAATSPLSPMANGG-RYLLSPPTSPGAMSVGSSYENTSPAFSPLSSP--ASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRP-----------SGSRSSDSPRLGRKGGHERPPSPG--LRGLLTDSPAATVLAEARRTTESPRLG-GQLPVVAISLSEYPSSGARSQPASIPGSPKFQSPVPAPRNKIGTLQDRPPSPFREPPGTERVLTSSPSRQLVGRTFS---------------DGLAATRTLQPPESPRLGRRGLD--SMRELPPLSPSLSRRALSPLPAR--------TAPDPKLSREVAESPRPRRWAAHGTSPEDFSLTLGARGRRTRSPSPT--LGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPRAQRKLSSG--DLRVPIP--RERKNSITEISDNEDELLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPETGELPSIGEATAALALAGRRPSRGLAGAIVVSGRCGEESGGASQRLWESMERSDEENLKEECSSTES---------------TQQEHEDAPGAKHQGEVLAVEEERAQVLGRVEQLKIRVKELEQQLQEAAREAEMERALLQGEREAERASLQKEQRAVDQLQEKLVALETGIQKDRDKE-------------------------------------------ADALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVSKRKERLAVLDSQAGQIRAQAVQESERLAREKNAALQLLQKEKEKLNVLERRYHSLTGGRPFPK--------------------------------------------TTSTLKEMEKLLLPAVDLEQWYQELMSGLGTGLAAASPRSSPPPLPAKASRQLQVYRS-KMDSDAASPLPRTRS-----GPLPSSSGSSSSSSQLSVATLGRS------------------------PSPKSALLAQN------------------------------------------GTSS--------------LPRNLAATLQDIETKRQLALQQK---------------GHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAGPFSAGP--SGFPALMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKSRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK-----------SPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63312-1", "uniprot_id": "PHLB1_RAT", "id": "Q63312-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LTLGARGRRTRSPSPT--LGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPHAQRKLSSG--DLRVPIP--RERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPETGELPSIGEATAALALAGRRPSRGLAGAIVVSGRSGEESGGASQRLWESMERSDEENLKEECSSTES---------------TQQEHEDAPSTKLQGEVLAVEEERAQVLGRVEQLKVRVKELEQQLQEAAREAEMERALLQGEREAERALLQKEQRAMDQLQEKLVALETGIQKERDKE-------------------------------------------ADALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVSKRKERLAVLDSQAGQIRAQAVQESERLAREKNAVLQLLQKEKEKLTVLERRYHSLTGGRPFPK--------------------------------------------TTSTLK-----------------------------------------------EVYRS-KMNGDMASPLPRTRS-----GPLPSSSGSSSSSSQLSVATLGRS------------------------PSPKSALLAQN------------------------------------------GTSS--------------LPRNLAATLQDIETKRQLALQQKVELPPAEPLSPEDPAGHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAAFPAGP--SGFPTLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKSRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK-----------SPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8N7TEA5-1", "uniprot_id": "A0A8N7TEA5_DANRE", "id": "A0A8N7TEA5-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "-----------------MDLNECEEMIDNSVDMDRMNRNVPEQGRQTHQVLQSTPLDLIETGKTLKVQAERPHLVSLGSGRLSTAITLLPLPEGKTTLG-HGNTDINIQGPGVMSQHCYIENVGA-VITLYPCGN-QCSMDGLAVTKPVRLAQGCMLCFGQSSFFRFNHPEEALRMKSLMPGGSPGFTNTYKN-HSETHGQLNGN--------HLPLHERSRPGAGTLVRSIEKDFQDIMNSLSMDDGQ---AEHCKKARHPIPQS---AMLNGSSRSLVSTPTSPGALSVSSSYENTSPPYSPLSTPSMVSS-------PGACLDS------ANTRSNSYTHTVQAPVPQPRNFTSKNCSSNGGLKDQESARIQ-KALTETPSSPGANRRGDNTHGSTSGS-------------------------SLVPGDLGRQVNTRFTSSSSASS--SPRSSIGSSVQE----------------SSSSIQSLS--------------------------RALLPPDSPQSSRRSVETSSIRELPPLSPSTSRRGILGVPVLPVALP---SVSLSSRGRTVPDSPRLQRRT-------TAEEEVGNTRLHTRSPSPVSTLLKDQSGSKQKGG--LSSAVG--SQTGVSPLTSPRNQRKAS---REARQVPPRTRERKNSISEVSDKEEDLLEYHRWQREERMREQEMERLERQRLETILNLCAEYNKSD-PPVGVDAGRVCLFPGMEEVSVRRPGP-------------DPVSVPGQ-SSHRQRESEEDNLKEECSSTES----------------QHQEHEDTSVLGQQERVYLEEERLRILARVDELKTRVTDLEQQIQESRQEAEMERALLQGERRAELDQVEAELEIINQLQLKLNEVENATQREKEKERAKVSAERDVLARLKDSYSELKGQLHKCPESLREHLQEQLTRKVEALESATKRFEDLEFRQLERESGIEEEKETVGRQLLQEKAEYHRNVAKRKEKMAALEIQANQLGLQAAQDCERMAKDRTLALQMLHKEKERLSSLEKRYQSLTGGKNFSKPTSTKEEVLYISEPDFLDELPTQNSLLPSSSTQRSTPQICSNRPQEEYLKLSDVYKMYGNGCVPAQTASPNS--LCLPLAVTSDTPREEYVTVSQLNQLFGMPKVDPYPTSSVQSFQAIDPAHSSHTSQCGSSQSLLVETQPAWSRPSIPRLDSERWYQEIMAAGQPSHSCPPPLPAKCLSS-----RKPMQMCKQ--DGETNGTLS-----------------GRNTPTKS----------LP-DLSPAYLDIDSKRQLDLQSR---------------GLYTCDDSRIRPMDHKLS-------HWGAPP------------SGAPMVHHSILHHQAP-----PAGESTYDTLSLESSDSVETSVSTGNNSACSPE---SSNGLAGLRLEEMEKMLKEAQQEKARLVESREREVQARKQMLEAERRRREEVERRLLDETAHRQRLVEEEVKMREKQCSQARPMTRYLPIRKEEFDLRSHVESSGHSVDTCAYVIVTEKMCKGHLVKMGGKIKSWKKRWFVFDRLKRTFSYYVDKHETKLKGVIYFQAIEEVYYDHLRSATK-----------SPNPSLTFCVKTHDRLYFMVAPSPEAMRIWMDVIVTGAEGYTQFMT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58HCC6-1", "uniprot_id": "A0AC58HCC6_DANRE", "id": "A0AC58HCC6-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "MRSHVEGLVSLAARKLLQDSHVPEQVSDSTLAMDTLNQNLS-HGHQSHQVLQSTPLDLIETGKALKVQAERPHLVSLGSGRLSTAITLLPLPEGKTTVG-HGAMDISIQGPGVAAQHCFIENRAG-IITLHPCGN-QCSMDGLPVNKPVRLSQGCMLCFGQSAFFRFNHPEEAFRMKSMMPEGGQTASVKNWT-HKDSENLVNGNHSSGEAKSHLVSNERVRPEHSAIVSSIEKDLQDIMDSLVMDDPQPSSSESKKPSSQSISQSPLSPMLNGGGRFLLSPPTSPGAMSVGSSYENNSPPFSPLSSPSAASSGSYTTLSPIGCQDQPHMLPPVPVRSSSYNYTSQPPIPQPRTILPSYSSGSSGPKVPESPRLQRKALLEAPPSPKPSRRGLNQDSSVAKTPDSPIQTHILPSVSISTAPTDVPSVSRVPVPGSPRLATKFSTASSPASPSSPRTKTTIVLQDRPSSPFREQPQPDRSLTSSPSHQLSPPSRSFQPPLDPIVHIIQGGPSHPHPRTLQPPESPRLARRNLEGSSMRELPPLSPSIARR---GVPVLPGALPGTLRTPESPSPRMVPESPRLRRKTGS-----PTEEPFSPRAMRTRSPSPTSGLTGESSGRKGSFGNSLSSAFSLSSLPGSSPRSSPRSHRKMSAGHRDLRMPHPGMRERKNSITEISDNEDDLLEYHRRQREERLREQEMERLERQRLETILNLCAEYNKGDGPPGDLGRMGVSGLGSRDGLNVRRPSM-------------DSVNSASLRATQRQRESQEDNLKEDSSSTESAQLDGRTPALLNGQNGQAEESLGSGSIGRLELGYLEEERVRVLAKVDELKARITELEQQLQESKQEAEMERALLQGERQAEMEQIETETEIINQLQRKLTELESSIQREKDKERANVDAEREALERLQDGYNELTSQLHNCPESLREQLQEQLKREAETLEAATKQFEDLEFQQLERESSLEEERETISQQLMQDRAQYHSSVAKRKEKVVALESQASQLGIQAAQECERLAKDRTITLQMLHKEKERLASLERRYQSLTGGKTFPK---------------------------------------SSNTIKEEYLKLSDVYKMYGSECHDIQLASASSHGLSLALDPAETAPREEYVTVGQLNQMYGMPKVESSPTSPVQSVQPSLADFPRLPSPHGSSLSLSFERQSDWGRPQMPVLDLEHWYQEVMAAGDVNQLCPPPLPAKAFSSSSSSPRRPVQVYRSRLDSDCSQSLLRPKVSAGLSPTYTTATLGRNTPSRSPLMVANSTGSLPRNLAATLQDIETKRQLALQQK---------------GQQVIEEQRRRLAELKQKAAVEAQCQWEALHGSQTQLHQPFSSSPAPALHHSILHHTAP-----PCGEQPYDTLSLESSDSMDTSISTGNNSACSPDNMSSASGMDALKIEEMEKMLKEAQLEKARLIESRERETQSRKLMLEEERRRREEAEKRLQEETLHRQQLIEKEVKMRARNFSQARPMTRYLPIRKEEFDLRSHIESSGHSVDTCYHVILTEKMCKGFLVKMGGKIKSWKKRWFVFDRLKRTFSYYADKHESKLKGVIYFQAIEEVYYDHLRSATKKGFFNLNL-TNSPTPTLTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX80-1", "uniprot_id": "Q9VX80_DROME", "id": "Q9VX80-1", "name": "PH domain-containing protein", "aln": "-------------------------------------------------------MSLTKKDPSLRVAASDPHLVSLGGGRLSTAVTIHYIHIGDTTIGSAASCSISLNGSGVRPLHCTIYRSDANEVTLVPEKDSRLLIDGAPILEETKLSQGAMITIGNSNYLRFNNPDEAQMMRSAMGSNERISMP------------------------QIDFTQSARQAHELSQSLELESFYESIINPINNPST-------YELECPKVFSSDLVTVNMPAKDVLGQKYASFARNLAENHRNEKQLNNQYAKGVGSNGGYWNVPSNAAIYKEQHQQQHQQAPQDLLTKVNND-------------------RYDRYPKAGGLQIYSMNGVNSDINNGPATGNNSGTG-------------------------GGAELEDMLKICTEYADRNNSMPSTHNVSSTSS-------------------ITSSPIVQNRIKTNG----------------------SLPRDKNKSPFPQQAGVASSANISLLSSSSGYENVRLLGPNRVEINGQIHVPASAGDGGSSSGVSSNALAP------TAAVRASHENLNQNHSATTGGKYVPQSPRTKIRTNCMSPKKDVSFGNAFALAISPPPLASSAVVSTSKPIPIP------------SMVKPPLAPKPPAPNQQRDYEQLFKSFERKQQQLDRMVPAKRSNKNINNLTLNLQSVESQTQSPKPS-RKPAP-------------APRSIHLEQRQRRELIQRRKQLKRELAELPP-----------------------SAGIEGLELKLGEQP----LAPSASPRLQLQALQNRVCRLEAQRNATRVMEENQQAKLKQSIEIKQDQLKKLRAMLKQKPNNACLKEELQ-----------------------------------------LVCESLESDRKTFEDLEFQYFEEESEHHASHEEFKR--QEQRLMLEAELAALRIQIGPDEEEPGSPTSPGSTGSNLVN---GVMSQSLFGSAELLCPKRRNQEDLMSKSVNEN----------------------------------------MFYNHKIEANTSTPKRLPLQLFEDLAGGSCEQISFNLSLQGDRFEVNPLERRVPSQDDIDRSCKVANDAPISASQGASTKIFDSIMEIERNRKLLLAQQGHQVIEHE------------------------RQKMYDLKKKS------------------------------------------HDEAR--------------TQYLLSTQQSMEQQRQLESDAN--------------GGKDAKLFEKTELQKLNQKPGEPVDDQVQKIAGDKENNVQNRKSTGSSPTTTTTTTTGGG----TTPQQQRHSQPELEHHAIALGIGGGGSGGAGGANQMVARSPRPLSEANNCDATIEAPKFANG--MDSSASPAVADNKRASSNSQDTASAGSGSGNSGSGGSTASDRKRVLP----KHQRPLTRYLPIFSPDLNLRHHIETAGHQIDPCPHVFVDAHSCRGYLHKLGATFHAWSRRWFVLDRQRSALIYYSDKSERKPRGGAYFATIDEVYLDHLNASKS------------GRPHCTFIVKTKKRSYNLQAASDSAARIWIDAIITGAQGNLDY--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .:.. : . :*. . . : ** . : . . * : * .::* ** :: :**:: : : *: .. : : *:*. . . . ..:**.: :. . .. * *: *. . : :: *:::: . : : *.: :.:: :: : :.:*: * . ..: : ::**: * ******: :*.** . .:* : ..: .:: : :: : :... . .: : * * . * * .:. ..* . : : :: *: . . . . . : .. : . * .: .:: :*** : . * . .: . . : . : .. : : :. .** . *...* ..: : . . :: : :: .: : ::* . . : : .. .. . :.: : .: **:***** . :::*: *:*::** :*.* :*.: : *:*.* *:*..:::*.:****:** : :: ** ** * * :* ** :*:*** ***.:: . * ** ***:.* * : *.* .* ***:*.*:***:* :: ", "identical_positions": 114, "similar_positions": 235, "identity": "6.78%" }, { "cls_id": "homologset.agr.RGD:620879", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61027-1", "uniprot_id": "RAB10_MOUSE", "id": "P61027-1", "name": "Ras-related protein Rab-10", "aln": "MA-----------KKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKE------PNSENVDISSGGGVTG-WKSKCC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61026-1", "uniprot_id": "RAB10_HUMAN", "id": "P61026-1", "name": "Ras-related protein Rab-10", "aln": "MA-----------KKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKE------PNSENVDISSGGGVTG-WKSKCC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P35281-1", "uniprot_id": "RAB10_RAT", "id": "P35281-1", "name": "Ras-related protein Rab-10", "aln": "MA-----------KKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIEIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDQHANEDVERMLLRNKCDMDHKRVVPKGKGEQIAREHRIRFFETSAKANINIEKAFLTLPEDILRKTPVKE------PNSENVDISSGGGVTG-WKSKCC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15971-1", "uniprot_id": "O15971_DROME", "id": "O15971-1", "name": "", "aln": "MA-----------KKTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVNKERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESA----ENQERVIIDRRNQEKAPGYSKCCA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07560-1", "uniprot_id": "SEC4_YEAST", "id": "P07560-1", "name": "Ras-related protein SEC4", "aln": "MSGLRTVSASSGNGKSYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDMET-RVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSNKLVGVGNGKEGNISINSGSGNSS--KSNCC-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *:** ::*:**********:*:*.** :* *..:**:** ********::.***:***:*********:****:********:****:*: ::* ** :*::.:::***::.: ::: **.** *** :** :*:* * *:*:*** : *::. * *.: * * .: :. .: *. . .. *:** ", "identical_positions": 98, "similar_positions": 62, "identity": "44.75%" }, { "cls_id": "homologset.agr.RGD:62088", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41232-1", "uniprot_id": "P2RY2_RAT", "id": "P41232-1", "name": "P2Y purinoceptor 2", "aln": "MAAGLDSWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYAQGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLSWGHARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSIILVCYVLMARRLLKPAYGTTG-LPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLS-CHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPATEPTPSPQARRKLGLHRPNRTDTVRKDLSISS-DDSRRTESTPAGSE-TKDIRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35383-1", "uniprot_id": "P2RY2_MOUSE", "id": "P35383-1", "name": "P2Y purinoceptor 2", "aln": "MAADLEPWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLS-CHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTEPTPSPQARRKLGLHRPNR--TVRKDLSVSS-DDSRRTESTPAGSE-TKDIRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41231-1", "uniprot_id": "P2RY2_HUMAN", "id": "P41231-1", "name": "P2Y purinoceptor 2", "aln": "MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLS-CHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z251-1", "uniprot_id": "A0A8M6Z251_DANRE", "id": "A0A8M6Z251-1", "name": "P2Y purinoceptor 2", "aln": "MAMN----NTTVS---TNDIDIYRCTLKEDFKYILLPVSYSLVFVFGLGLNITAMYVILFRTKHWKPNTIYMINLNACDTLYILTLPFLIYYYAGANAWPFGDPMCRFIRFFFYTNLYGSILFLSCISVHRFIGVCHPVRSLSWMNARRARWISVGIWLIILILQTPLLYFSRTRLNDEVLVCHDTTIKELFDDFLVYSSVVMLLLFVLPFGVVLVCNFLIVKKLREPGVGDAPTSQRSKQKSVKMIIIVLVAFMLCFLPFHVNRSVYYTLRYLDQANCTVIRLSNNVYKATRPLVSFNSCIDPILYFMAGQ---SFRKSIKKTS---------------------SQRYDKSMSTY---------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . * *:. .* *:* ::*****:******.:* * ** ** .*:*::* * * *:..* **::* ..*:** :**:*:**** .: ***. :*:::**:****** *****:****** :** :*::** * .** ** :: :*:::* *:*:*** * .. :.****: ***. *:.****:: ***.:**.::*** .*:.::* :*. * : *:*:***: * :**..* ********.*::**::* ** : * .:. * .** ****.* ***:**:***:*** * :. * .: * : :.: ", "identical_positions": 155, "similar_positions": 98, "identity": "41.01%" }, { "cls_id": "homologset.agr.RGD:620880", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DD03-1", "uniprot_id": "RAB13_MOUSE", "id": "Q9DD03-1", "name": "Ras-related protein Rab-13", "aln": "------------MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKIRTVDIEGKRIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRQVQREQAEKLAREHRIRFFETSAKSSVNVDEAFSSLARDILLKTGGRRSGTNSKPSSTGLKTSD-KKK-NKCLLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35286-1", "uniprot_id": "RAB13_RAT", "id": "P35286-1", "name": "Ras-related protein Rab-13", "aln": "------------MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKIRTVEIEGKRIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRKVQREQAERLAREHRIRFFETSAKSSVNVDEAFSSLARDILLKTGGRRSGNSSKPSSTDLKVSD-KKNSNKCSLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51153-1", "uniprot_id": "RAB13_HUMAN", "id": "P51153-1", "name": "Ras-related protein Rab-13", "aln": "------------MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGNGNKPPSTDLKTCD-KKNTNKCSLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3A4-1", "uniprot_id": "RAB13_DANRE", "id": "Q7T3A4-1", "name": "Ras-related protein Rab-13", "aln": "------------MAKKYDFLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKVKTIEVEGKKVKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSYENIQNWMKSIKENASAGVSRMLLGNKCDIEAKRKVSKETGEKLAKEHGIRFFETSAKSSINVEESFTSLARDILLKSN-KKPGPSGR--EVKLTSTE-KKSSSKCLLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07560-1", "uniprot_id": "SEC4_YEAST", "id": "P07560-1", "name": "Ras-related protein SEC4", "aln": "MSGLRTVSASSGNGKSYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDMET-RVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSNKLVGVGNGKEGNISINSGSGNSSKSNCC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* ** ::*:**********:**::**.**:** ::*:*******::*::::**::***:*********:******************:***::: **::*:*:::*:*. .. :*:***.*:*: * * : .: **:* * *:*:***.. **:* * :**: * * . .: .. . :. . . . .*. ", "identical_positions": 98, "similar_positions": 65, "identity": "45.37%" }, { "cls_id": "homologset.agr.RGD:620881", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61106-1", "uniprot_id": "RAB14_HUMAN", "id": "P61106-1", "name": "Ras-related protein Rab-14", "aln": "------------------------MATAPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQGGRLTSEPQPQREGCGC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91V41-1", "uniprot_id": "RAB14_MOUSE", "id": "Q91V41-1", "name": "Ras-related protein Rab-14", "aln": "------------------------MATAPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQGGRLTSEPQPQREGCGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LXD4-1", "uniprot_id": "A0ABK0LXD4_RAT", "id": "A0ABK0LXD4-1", "name": "Ras-related protein Rab-14", "aln": "------------------------MATAPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQGGRLTSEPQPQREGCGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1PEV5-1", "uniprot_id": "A0A8M1PEV5_DANRE", "id": "A0A8M1PEV5-1", "name": "Ras-related protein Rab-14", "aln": "------------------------MATAPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIMEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQGGRLTSETQPQREGCGC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BK8-1", "uniprot_id": "Q86BK8_DROME", "id": "Q86BK8-1", "name": "Ras-related protein Rab-14", "aln": "MSKVRSVVNKLHERIDYFIEKCPNMTAAPYNYNYIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDLESTREVTYEEAKEFADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQEGRLDLNASESGVQHRPSQPSRTSLSSEATGAKDQCSC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::*****.*****************************:*************:**..:**************************************************:******.***:*****:***: *:*******:**:****:****** **:***:****:*:*******:* *****:******:** *. *:**. :: *.*", "identical_positions": 174, "similar_positions": 30, "identity": "72.8%" }, { "cls_id": "homologset.agr.RGD:620883", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61865-1", "uniprot_id": "MIA_MOUSE", "id": "Q61865-1", "name": "Melanoma-derived growth regulatory protein", "aln": "MVWSPVLLG-IVVLSVFSGPSRADRAMPKLADWKLCADEECSHPISMAVALQDYVAPDCRFLTIYRGQVVYVFSKLKGRGRLFWGGSVQGGYYGDLAARLGYFPSSIVREDLTLKPGKIDMKTDQWDFYCQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62946-1", "uniprot_id": "MIA_RAT", "id": "Q62946-1", "name": "Melanoma-derived growth regulatory protein", "aln": "MVCSPVLLG-IVILSVFSGLSRADRAMPKLADRKLCADEECSHPISMAVALQDYVAPDCRFLTIYRGQVVYVFSKLKGRGRLFWGGSVQGDYYGDLAAHLGYFPSSIVREDLTLKPGKVDMKTDEWDFYCQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16674-1", "uniprot_id": "MIA_HUMAN", "id": "Q16674-1", "name": "Melanoma-derived growth regulatory protein", "aln": "MARSLVCLGVIILLSAFSGPGVRGGPMPKLADRKLCADQECSHPISMAVALQDYMAPDCRFLTIHRGQVVYVFSKLKGRGRLFWGGSVQGDYYGDLAARLGYFPSSIVREDQTLKPGKVDVKTDKWDFYCQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * * ** *::**.*** . . .****** *****:***************:*********:*************************.*******:************ ******:*:***:******", "identical_positions": 106, "similar_positions": 15, "identity": "80.92%" }, { "cls_id": "homologset.agr.RGD:620886", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9I7K8-1", "uniprot_id": "Q9I7K8_DROME", "id": "Q9I7K8-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "--------------------------------------------------------------------------MVICEIEFCNNSQGIFYAGQLISGQVVIKTEKEKSVKAVILN--------IKGYAETHWAD----------TEHDPDDQSNGE--------------------------------------------------------------SFNGHVDYLATRAYLHGS------SSSIEVLIE----------------------------------------------------------------------------------------------PGTSSYRFACQLPIT--CPSSFEGTLGRIRYLVNVRFVRPWKFDLNFNRCFTV--IKVMDLNSESLMLRVPSQVESQRTFCCFPCRSSPLSMRLSVPQSG-------------------------------------FVPGQIVPVEVMVSNDSG-VAVEDITVKLTMVVIYYSQ----------------------------------------------------PPSA-DTNKDRFEMVLKTGGGVSTKCRQ---------QFTFDLKVPPTPP-----------TCFNLCSIIQIGYQVEAEARVKGCHGGQSLHMPITIG--------SVPLT-KQLQKE--PRTWGEVLPPQQLDAKALILIGSEQNGEALGSPNPWAADP-------------SIAPPSYAEAKHISPDPHKFSKSKKKSQKRGVKG--SQERKAETIVFSPLYAVFDLSNQVDEMTLRANEPKTDG-----GYVNEGVEKSTWL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQV1-1", "uniprot_id": "A8JQV1_DROME", "id": "A8JQV1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-------------------------------------------------------------------------MGIICQILFHNNTQGVFYAGQMVAGQVTLSTDKAIQIKAIRLK--------LKGYAETHWTE----------SKTDSNNKSTSE--------------------------------------------------------------SYNGFEKYLSSKVYLLGS------EISPEMALE----------------------------------------------------------------------------------------------PGTRSYNFACPIPIN--CPSSFEGTHGRIRYMVDVNIIQPWKYDSIFSRAFTV--IQVMDINTYNSVSQVPVQAKTEKTFGVWPFRSDPLTLELNLPQTG-------------------------------------FVPGQTVPANVLIGNESK-IRVHEVKVGLSMMITYYSD----------------------------------------------------LSSG-SKCERKSVAKLKADG-VLRNSRK---------MYDFQLMIPSTPP-----------SCFHLCRIIKIGYQIEVVAKVKGMHINGTLIMPVTIC--------GVPISPSAVQYT--PQSSGPEAPEQ----RALTLIEGEGAFAPAAPPYPWSEGS-------------TLSPPNYAEAMHSHSDSEKQSESGNAQEKS----------------YKPLYPVFDLSTSTVEKSKEAALDKEE-------------KK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L0-1", "uniprot_id": "Q9I7L0_DROME", "id": "Q9I7L0-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-------------------------------------------------------------------------MTVTCEIDFDNNPHGTYFGGEVLTGRVTLKLDKMKLVKAITLN--------ITGYAETRWIE----------RVT-TNRRRRRR--------------------------------------------------------------TFCGREDYIASKTFLVGS------NLSSQVSIE----------------------------------------------------------------------------------------------AGIHTYNFVCLIPTE--CPSSFEGSHGRVRYMATVTLVRPWKFDQSYTRCFTV--LKVMDLNFDSPLLRVPAHSETSKTYCCWPCRSDPLALQLTVPQTG-------------------------------------FVPGQNVPLSVLVTNDSH-IPVEQLLISFVMLVTYHSK----------------------------------------------------PPSMPNTTSERLVVNTFKGDAVQRNCKK---------LFSYEIRVPATPP-----------TCFNLCGIIQIAYQVEVEARVKGCHNNEVVTIPLTIG--------SVPLA-QHVPIQ--PRGFVPQLNVN--------ELAVEEVATAPNSSSPWSVDA-------------SIPPPNYQEAVHMRSTAATRSDDLDDPEPVPPN-----TLSLDGGAYKPLYPVFDIPSPSAPPPTDYTQNYMAERAFVNPAMDVDKDKGTWL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7L1-1", "uniprot_id": "Q9I7L1_DROME", "id": "Q9I7L1-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-------------------------------------------------------------------------MVVTCEISFDNNKHGTFYAGQLVKGCATLKCDRSKEVQAVLLK--------VVGYSITKWSE----------KSLGSTKL-------------------------------------------------------------------YVGREDYLSSNTYLVGSEQNNTHNNTHRLTIE----------------------------------------------------------------------------------------------AGVHSYNFTCQLPYQ--CPSSFEGRHGCIRYIVKVLLIRPWKFDQAYTKGFTV--LKMLDLNFDTPQLKSAAHSEGYRTFCCGPCKTDPLKLELHLPQAG-------------------------------------YVPGQKIPVTIVVVNNTA-VAVSEIRLSLVMLVRYYSV----------------------------------------------------SPEH--SRVERLIISRAKGESVLKQCTR---------SQTIDLPVPSTPP-----------TCVELSNLIQIAYQLEVEALVKSLREQQLMVMPVTVG--------TIPLAVSGIVVQQPPRRSAHYEGPDS-RRNPPDELPMVTALESLPSDLASSAAD-------------SALP-NYEESRHTQRGNINEEELHAFGSNE----------------FAPLYPVYSIPSPTPVLTANARNAGFVN---------QSFVK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VI53-1", "uniprot_id": "Q9VI53_DROME", "id": "Q9VI53-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "------------------------------------------------------------------------MGLKGCELQLDN-PWNTYYAGQTVNGQVKFTFDSPKKVRGIIIR--------FLGEANTEWSE----------EKSVTTSEGKTENEVT----------------------------------------------------------QLKGHEEYFKIQYYLLGG------KNSSETELP----------------------------------------------------------------------------------------------PGTHTYPFTCALPPN--LPSSFEGEFGHVRYTIKVTLDRPWKFDQDMKMAFTV--IAPVDLNLN-PRVKEPFKLELEKSFCCFCCRSGPLAVITNIPQTG-------------------------------------FVSGQVLPITCEVDNTSN-VNLTAVKFELRKLVTFHTN----------------------------------------------------QPRS-EKRESKVIIANLSVGPVNGGESR---------TFTQQMEIPALPP-----------TNLLNCGIIALDYDLHVECEVSGPHRNLTGKVPITLG--------TIPLAGVRPPTQFTDAPSAVQSEDPSLAPTQPVSPASPPGGDGVGGALGWNVADSTGGGSLY----PNIPPPQFVETQYRAPTIAGRDDSEHTQMIG-------------DGAFAPRYPTFQFNNATAPPASQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8BG60-1", "uniprot_id": "TXNIP_MOUSE", "id": "Q8BG60-1", "name": "Thioredoxin-interacting protein", "aln": "---------------------------------------------------------------------MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRIL--------ACGVAKVLWMQ----------GSQ-----------------------------------------------------------------------QCKQTLDYLRYEDTLLLEEQPTAGENEMVIMRP----------------------------------------------------------------------------------------------GNKYEYKFGFELPQGP-LGTSFKGKYGCVDYWVKAFLDRPSQPTQEAKKNFEV--MDLVDVNTP--DLMAPVSAKKEKKVSCMFIPDGRVSVSARIDRKG-------------------------------------FCEGDDISIHADFEN-----TCSRIVVPKAAIVARHTY----------------------------------------------------LANGQTKVFTQKLSSVRGNHIISGTCAS---------WRGKSLRVQKIRP-----------SILG-CNILKVEYSLLIYVSVPGSK-KVILDLPLVIG--------SRSGLSSRTSSMASRTSS---------------EMSWIDLNIPDTPEAPPCYMD--------------IIPEDHRLESPTTPLLDDVDDSQDSPIFM----------------YAPEFQFMPPPTYTEVDPCVLNNNNNNNNVQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M7W1-1", "uniprot_id": "TXNIP_RAT", "id": "Q5M7W1-1", "name": "Thioredoxin-interacting protein", "aln": "---------------------------------------------------------------------MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVTVEVCEVTRVKAVRIL--------ACGVAKVLWMQ----------GSQ-----------------------------------------------------------------------QCKQTLDYLRYEDTLLLEDQPT-GENEMVIMRP----------------------------------------------------------------------------------------------GNKYEYKFGFELPQGP-LGTSFKGKYGCVDYWVKAFLDRPSQPTQEAKKNFEV--MDLVDVNTP--DLMAPVSAKKEKKVSCMFIPDGRVSVSARIDRKG-------------------------------------FCEGDDISIHADFEN-----TCSRIVVPKAAIVARHTY----------------------------------------------------LANGQTKVLTQKLSSVRGNHIISGTCAS---------WRGKSLRVQKIRP-----------SILG-CNILRVEYSLLIYVSVPGSK-KVILDLPLVIG--------SRSGLSSRTSSMASRTSS---------------EMSWIDLNIPDTPEAPPCYMD--------------VIPEDHRLESPTTPLLDDVDDSQDSPIFM----------------YAPEFQFMPPPTYTEVDPCVLNNNNNN--VQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H3M7-1", "uniprot_id": "TXNIP_HUMAN", "id": "Q9H3M7-1", "name": "Thioredoxin-interacting protein", "aln": "---------------------------------------------------------------------MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRIL--------ACGVAKVLWMQ----------GSQ-----------------------------------------------------------------------QCKQTSEYLRYEDTLLLEDQPT-GENEMVIMRP----------------------------------------------------------------------------------------------GNKYEYKFGFELPQGP-LGTSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEV--VDLVDVNTP--DLMAPVSAKKEKKVSCMFIPDGRVSVSARIDRKG-------------------------------------FCEGDEISIHADFEN-----TCSRIVVPKAAIVARHTY----------------------------------------------------LANGQTKVLTQKLSSVRGNHIISGTCAS---------WRGKSLRVQKIRP-----------SILG-CNILRVEYSLLIYVSVPGSK-KVILDLPLVIG--------SRSGLSSRTSSMASRTSS---------------EMSWVDLNIPDTPEAPPCYMD--------------VIPEDHRLESPTTPLLDDMDGSQDSPIFM----------------YAPEFKFMPPPTYTEVDPCILNNNVQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47029-1", "uniprot_id": "ALY2_YEAST", "id": "P47029-1", "name": "Arrestin-related trafficking adapter 3", "aln": "----------------------------------MPMDQSISSPLFPMEKDIDIPLDATPLAQSSSLQLFIHLAEPVVFLQGFDPQ-KTEYPSVVLRGCLVVRILKPTKLKSISLS--------FKGYSRTEWPE----------GIPPKRQEFVEIKDIVDHTWALYPPTEQKSKKKMDASAPNESNN----AANNFLTKESGASLYRTLSDNETITSRKNSISGLSSLNLSPLGAPGNSSVNVKDRESRQRSRSSSVTSSNGPSRNLSPINLLKRATSPSVSHHNY---KPTTTSIFSDLLNNTFTHNDAASHHGHHIPTSSNHLAMTSNNFTSGSGGEFFVFQPGDYIYAFEELIPQA--YPESIKADFGFVEYFLFASIERPGAFKSNISARQVV--NIVR--------TQAHNSVEESEPIIISRDWENQLYYDIVIASKD-------------------------------------IILDAFLPITFKFAPLDK-VTLHRIRIYVTETMEYYCR---------------------------EKKVHRMEPTKKFLLTEQKGPKLPNLPNDANLSKAKNMGNLLQDPKNGDLVNK---------EYEYQIFIPSRFNNHQQLHPDTSYENIKANHWIKICLRLSRVVDNKRKHYEISIDSPIHVL--------HRLCSHANTLLPSYDGHPASFPKETDSSISSILESSDDNINLYHNSNIFFPKEVLSSPVLSPNVQPLDILIP-HLPSTSLTRNSRQFNRN---SKSHPSDNTIFNSAKLKSNIYQPESLQRELASPQAIPLSPITSPMSN----MEVPPPDFDFSSDFISDAASGTTTTEVSSSESSIL-----PRDPPSYKDTVLHDNNQKRRPNSKHPTPPSLKASHPNKNSDKNSSETLNK-KESMSKIEENKHKRETTPKKRENRDVKSLSTPQREESKDSTSTGNQSNEKNRKRVLSLSSSLHSSPNNSGFAHSALGNLSNESLRSLNRRESVQDNLPSTIRHDNPFFTDLNQVLIEDELKNHDKNELNRHSTNTSSTPASARSSFDYSGINISKDKLNMEPLLSKTETLTNKVNEDSFLRPNDSYVDLLEPSVDTTIDITAPYARNSSAWHPLQNDNDNNQFSPLLGSNENFLNAANAQNSAESDHNNDIFTQGSGLTESSKNSDSEERFISRLSSPEKVLINTLDNESGLQSINESTL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36117-1", "uniprot_id": "ALY1_YEAST", "id": "P36117-1", "name": "Arrestin-related trafficking adapter 6", "aln": "-------------------------------MLQFNTENDTVAPVFPMEQDINAAPDAVPLVQTTTLQVFVKLAEPIVFLKGFETNGLSEIAPSILRGSLIVRVLKPNKLKSISIT--------FKGISRTEWPE----------GIPPKREEFSDVETVVNHTWPFYQADDGMNSFTLEHHSSNNSSNRPSMSDEDYLLEKSGASVYIPPTAE---PPKDNSNLSLDAYERNSLSSDNLSNKPVSSDVSHDDSKLLAIQKTPLPSS--------SRRGSVPANFHGN---SLSPHTFISDLFTKTFSNSGATPSP----EQEDNYLTPSKD------SKEVFIFRPGDYIYTFEQPISQS--YPESIKANFGSVEYKLSIDIERFGAFKSTIHTQLPI--KVVR--------LPSDGSVEETEAIAISKDWKDLLHYDVVIFSKE-------------------------------------IVLNAFLPIDFHFAPLDK-VTLHRIRIYLTESMEYTCNSNGN-----------------------HEKARRLEPTKKFLLAEHNGPKLPHIPAGSNPLKAKNRGNILLDEKSGDLVNK---------DFQFEVFVPSKFTNSIRLHPDTNYDKIKAHHWIKICLRLSKKYGDNRKHFEISIDSPIHIL--------NQLCSHANTLLPSYESHFQYCDEDGNFAP----AADQQNYASHHDSNIFFPKEVLSSPVLSPNVQKMNIRIPSDLPVVRNRAESVKKSKSDNTSKKNDQSSNVFASKQLVANIYKPNQIPRELTSPQALPLSPITSPILNYQPLSNSPPPDFDFD------------LAKRGAADSHAI-----PVDPPSYFDVLKADG---------------IELPYYDTSSSKIPELKLNKSRETLASIEEDSFNGWSQIDDLSDEDDNDGDIASGFNFKLSTSAPSENVNSHTPILQSLNMSLDGRKKNRASLHATS-------------------VLPSTIRQNNQHFNDINQMLGSSDEDAFPKS-----------------QSLNFN---------KKLPILKINDNVIQSNSN------SNNRVDNPEDTVDSSVDITAFYDPRMSSDSKFDWEVSKNHVDP----------AAYSVNVASENRVLDDFKK--AFREKRK-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q02805-1", "uniprot_id": "ROD1_YEAST", "id": "Q02805-1", "name": "Protein ROD1", "aln": "------------------------------------------------------MFSSSSRPSKEPLLFDIRLRNLDNDVLLIKGPPDEASS-VLLSGTIVLSITEPIQIKSLALR--------LFGRLRLNIPT-------VLQTVHGPHKRYSKFERNIYS--------------------------------------------------------HFWDDFNIKSYFQNLYDNHNNGKITISSKSSTNLAALPKRKRALSTASLIS-------------------------------------------------------------SNGQTSASKNYHTLVKGNYEFPFSAIIPGSL-VESVEGLPNAAVTYALEATIERPK-QPDLICKKHLR--VIRT---------LAIDAVELSETVSVDNSWPEKVDYTISIPTKA-------------------------------------IAIGSSTMINILIVPILKGLKLGPVRISLVENSQYCGS------------------------------------------------------YGGVINQERMVAKLKLKDPLKHVAQI---------KKKRSLNEAADEG--------VDTDTGEFQDKWEVRALLNIPASLTKCSQDCRILSNIKVR--------HKIKFTISLLNPDGHISELRAALPVQLFISPFVPVNVKTSDVIERTLKTFGPSYQVTSQHDNSFSSKNFVDDSEEDVIFQRSASALQLSSMPTIVSGSTLNINSTDAEATAVADTTMVTSLMVPPNYGNHVYDRVYGEVTNEDETSASASSSAVESQAIHNIQNLYISDSNNSNNPILA-----PNPQIKIEDD---------------------SLNNCDSRGDSVNNSNLN-LVNSNLTISENWNNNSPSANRYNNIINAGLNSPSLTPSFAHLSRRNSYSRQTSS--TSLKNDLELTDLSRVPSYDKAMKSDMIGEDLPPAYPEEELGVQENKKIELERPQILHHKSTSSLLPLPGSSKSSNNLKRSSSRTHLSHSPLPRNNSGSSVSLQQLARNNTDSSFNLNLSFTSAKSSTGSRHFPFNMTTSFTSNSSSKNNSHFDKTDSTSDANKPREEENYTSATHNRRSRSSSVRSNNSNSPLRQGTGSFANLMEMFTKRDRS--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P43602-1", "uniprot_id": "ROG3_YEAST", "id": "P43602-1", "name": "Protein ROG3", "aln": "-----------------------------------------------------MGFSSGKSTKKKPLLFDIRLKNVDNDVILLKGPPNEAPS-VLLSGCIVLSINEPMQIKSISLR--------LYGKIQIDVPLERPQ-DASSSSLSSSPPKIRKYNKVFYN--------------------------------------------------------YAWDNVNLKEYLSGLRGQSG---LAGSSSSSN---ILGTRQRAQSTSSLKS-------------------------------------------------------------LKGSSSPSS--CTLDKGNYDFPFSAILPGSL-PESVESLPNCFVTYSMESVIERSKNYSDLICRKNIR--VLRT---------ISPAAVELSETVCVDNSWPDKVDYSISVPNKA-------------------------------------VAIGSATPINISIVPLSKGLKLGSIKVVLFENYQYCDP------------------------------------------------------FPPVISENRQVTELNLEDPLNESSGE---------FNGN--GCFVNNP--------FFQPDHSFQDKWEIDTILQIPNSLSNCVQDCDVRSNIKVR--------HKLKFFIILINPDGHKSELRASLPIQLFISPFVALSIKP-----LSSSNLYSLFSTTNQKD-----ENSSQEEEEEYLFSRSASVTGLELLADMRSGGSVPT---------------ISDLMTPPNYEMHVYDRLYSGSFTRTAVETSGTCTPLGSECST------VEDQQQDLEDLRI-----RLTKIRNQRD---------------------NLGLPPSASSAAASRSLSPLLNVPAPEDGTERILPQSALGPNSGSVPGVHS-NVSPVLLSRSPAPSVSAHEVLPVPSGLNYPETQNLNKVPSYGKAMKYDIIGEDLPPSYPCAIQNVQPRK------PSRVHSRNSSTTL--------------SSSIPTSFHSSSFMSSTASPISIINGSRS----------------SSSGVSLNTLNELTSKTSNNPS----------------------------------SNSMK----RSPTRRRATSLAGFMGGFLSKGNKR-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VI00-1", "uniprot_id": "Q9VI00_DROME", "id": "Q9VI00-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "--------------------------------------------------------------------------MPSSCSFELDRREPIYYSGETVNGRAILTTTSEKSVNEVYIL--------FEGEAKVRWDE----------RRTRTRGGKTEHYT-----------------------------------------------------------EYFRGKQQYLYTRTSVFGSGNLP---------------------------------------------------------------------------------------------------------PGTHTYNFCIPLPLE--CPSSVVAQYGKIFYEVSVVIDRQWRFNNVFKQPLTV--IQTYNLNMS-PQLLMPLVREDIKHFCCWPCSSGPVLSTLTIPFGG-------------------------------------YAPGQKIRFTLEIDNQSSGYDLNGIELKLKQIYKFQAQ----------------------------------------------------TPHHKTREKEHSLNKSCQQERVLRLSKK---------KIEGTLAIPAVPP------------SSRTEGIISVSYQVILTISTGDCHVDSDFEVPIVIG--------TIPLIQSAENPASAAQWIP----------------ETPDTPAGAAADLPPSYDK--------------CKPPTFEEATNFGERFIDIDQDEHNRTDDFIP-------------RYPMYTNFAMPSAPPQPPEEFATNQPVPVLSLPHDPTAPLVGQNNTDRPTQSYGWNTNS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KGD9-1", "uniprot_id": "A0A0B4KGD9_DROME", "id": "A0A0B4KGD9-1", "name": "Arrestin C-terminal-like domain-containing protein", "aln": "-------------------------------------------------------------------------MPIECLISFDNNPQGVYYAGQELSGVVDLSVDATKRIKGIHVT--------VSGYAKIRWIK----------KGYPRDSER----------------------------------------------------------------AMCRAYRSYLSSRSYVLGS-----CANNSSIDWP----------------------------------------------------------------------------------------------AGEYSYTFHVILPDN--LPTSFDGKYGQIHYEIITTIERAARHPKVFKLPFTV--IQPLDLNAD-AIYRVPLEILDRKRFWSFCCPTGPLTVKFSTPYCG-------------------------------------YAPGQKIHFVLYINNESS-IDIIECEVKLKQEVSYESH-----------------------------------------------------DPQHEYRYDKHLIARKQFGNVLRWSRK---------VYRGYLDLPSIPP-----------TSVKPTCPISVNYSIKIIVNPTEFHWKLKLKIPLTIG--------SIPIMDGPEALLRFNRQQQQHQVVSQN-----LQMSTQQRQRDRDRDRDMNVDR-------------ERDRDRDRDRISASVQQRRISSINNNNNNHGRLVG----------GLLPTNSNMNMITNVSPTPTSSTPSSTPTTAALRPTAMPAILVTSDSDNPPDYIPMMPPSYEDAMAL-----SEKFS----------------------------DDTEFLTNVSMSSILSAQADVTTSEPFKPRYPVYYDYETPTIPPETLYDESSSRLRLTLSCQDSAAPETDEDLAPNTRGGEPPSCEKK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12502-1", "uniprot_id": "LDB19_YEAST", "id": "Q12502-1", "name": "Protein LDB19", "aln": "-----------------------------------------------MAFSRLTSTHQSNHNGYSNSNKKGQSLPLTLSIDVESPPCVLYGSAMESSGAVLSGLFTVTVVDPYSSA--------EDKSLKNTESN---------VSTTSKSLKRKSTFG-----------------------------------------------------------SALSSRLSSLSASTSNISPSTSSTSISHSPTPAN------------------------------------------------------------------------------------------LRIMAGYTKITITSVTLSLV-QKIHFHKPFVPNISSMQTCMNCKTKITNMKSWEIQSN-TQDLSVGSHSYPFSYLIPGSVPCSSSLGATAETQVKYELIAVVTY-------------------------------------IDPHRNSFSSGHSTPRKEGSSSKKRLLQLAMPIAVTRS----------------------------------------------------IPRGPDKNSLRVFPPTELTAAAVLPNVV---------YPKSTFPLEMKLDG--------VSSGDRRWRMRKLSWRIEETTRVKAHACPVHKHELRQLE--------EQVKIKESEKSKKPRSHIKRYGELGPQIRVAVNSLENMPSQRLPGEPGREQAPNSSGPASTGNVGLDDENPVNEDEEDQPGSEFIHPSDDALRQELLMQQQR---------ARQQQLQQELKNNSSLFTEEVRIISKGEMKSGWKTDFDNNGKIELVTEIDCMGLNSGVSNPVMHASTL-----QTPSTGNKKPSIN-----------------VACDIQDPNLGLYVSHILAVEIVVAEETLQYANGQPIRKPNSKNKKETNNNTMNVHNPDQRLAELSPIFANRNTPKVRRMGPEDITPVNSNKSNHSTNKEKASNGASNSNIVSVPTGAARVLRMQFRLTVTERSGLGISWDEEVPPIYQDVELLSPPCYELSINNGIKNKLYSTMSTPVRSEDDFVGGSDEDIGNYESQGLEPGPNVQEVTITQNKLTIPPTAHHYQPASSSQRSLTTVQSPPLESVVSVQGSVPFRGHVLTPHSTRDIRIQNFSDFLDSNRITQ------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38167-1", "uniprot_id": "ECM21_YEAST", "id": "P38167-1", "name": "Protein ECM21", "aln": "-------------MPFITSRPVAKNSSHSLSETDLNQSKGQPFQPSPTKKLGSMQQRRRSSTIRHALSSLLGGANVHSPAVLNNTTKGGNNNGNIRSSNTDAQLLGKKQNKQPPPN--------ARRHSTTAIQGSISDSATTTPRSSTSDTNRRTSGRLSVDQEPRISGGRYSQIEEDSTVLDFDDDHNSSAVVSSDLSSTSLTRLANSKKFNEQFLIEYLTARGLLGPKTVLSNEYLKISISTSGESVFLPTISSNDDEYLSRLNGLNDG----TDDAEADFFMDG---IDQQEGNTPSLATTAAATESGGSINENRDTLLRENNSGDHPGSGSELNTRSVEIDSSMVSYSIAVIVSVK--KPTRFTDMQLELCSRVKVFWNTGVPPTKTFNEEFYNAASMKWNLNDENFDLFVPLSISPDDQMIENNSNDRQMRLFKNIPTEERLYLDKTKTKAS--LLNAIDVNKTHLYQPGDYVFLVPVVFSNHIPETIYLPSARVSYRLRLATKAINRKGFYRQDSNSP-----------------------QPIVSPDSSSSLSSTTSSLKLTETESAQAHRRISNTLFSKVKNHLHMSSHQLKNEESGEEDIFAEYPIKVIRTPPP---VAVSTANKPIYINRVWTDSLSYEISFAQKYVSLNSEVPIKIKLAPICKNVCVKRIHVSITERVTFVSKGYEYEYDQTDPVAKDPYNPYYLDFASKRRKERSVSLFEIRTKEKGTRALREEIVENSFNDNLLSYSPFDDDSDSKGNPKERLGITEP---IIIETKLKFPKYEDLDKRTAKIIPPYGIDAYTSIPNPEHAVANGPSHRRPSVIGFLSGHKGSKSHEENEKPVY-----DPKFHQTIIKSNSGLPVKTHTRLNTPKRGLYLDSLHFSNVYCRHKLEIMLRISKPDPECPSKLRHYEVLIDTPIFLVSEQCNSGNMELPTYDMATMEGKGNQVPLSMNSDFFGNTCPPPPTFEEAISVPASPIVSPMGSPNIMASYDPDLLSIQQLNLSRTTSVSGPSGYSDDAGVPNVNRNSISNANAMNGSISNSAFVSGNSGQGVARARATSVNDRSRFNNLDKLLSTPSPVNRSHNSSPTNGLSQANGTVRIPNATTENSKDKQNEFFKKGYTLANVKDDEEQEGIVSSSSADSLLSHGNEPPRYDEIVPLMSDEE-------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12734-1", "uniprot_id": "CSR2_YEAST", "id": "Q12734-1", "name": "Transcription factor CSR2", "aln": "MQSTVPIAIASNGNKRDVVQNVSAGDEGDILQRLARNREMISTSLSPQKSSGFSGRRRSSSVRDALSSFFGTGNSPTSSMDDYSNLMNRNYSTASTAMCRGNSFPSDVGTKAYNITGSYQPDRHRNSVPYTTIDQLHTRQDTGLRRESDPVAAKQISSNNDIVRSFITHHASNSTMFINRVLSDYLADRGFIKQTPLYNKKSVLEISIATSAESVFLPTTKSDETEYLSLIHGSLNQARTQPVGSTNTAESDFLPSCPTMDTLNENNDLSLFPLHTQRTSPSNTARTGNAMDTSNSDRASPASNNNTTDADSFVASGNNNPMNNNNSPARNRHPNSHSRSLPNAWNSQMPSFSFALIFSLN--KSTTLSDIKVELTSNVRVVWFNGLPPTKNVNEECYNIGSLDWTLNADNFNLFIPQGAKSPLDIVENHSNNRKLKVLQKLSMRKRRSFSNKAVLRENILNNLNASNSTNKLNAGVYVFTIPIVLASRIPESLYYPSARVSYSLRLATKLKDEHTQLVASRPRSSSISSPQKLRSYSCSDSYEYSQIDDTIEGETYNNDKNSTGKIAFPSSWLKSAKGRLKRNNSNGRSDNNGASSSGLAMQHDSEDTINLQYPLNLVRTPPEIS---VTTANKPLYINKVWENCLSYEISFAQKYVPLNGEIPITIKVAPLVKSLSVKRIRVSCREKISYRSKDYQYDFDQLDPLASDPCNPYHMRYLVRKKKDRSLPLFEVASKCTSGPSIREEVVTNTVDDNLLAYTSSKENNKDIPFSESFTVKTK----------LKFPKYCEVDATKAASLPPYGIDLFDPIKDPTQSENTSNNGNVLGFLVGRPNRASKTVHKIPQDKNHNEVNDTNGNSNTSLQTSSNVPIQHYTRLNKPRRGLYLDSMHFKNIQCSHKLEIVLRVSKTDSGSSKIIRHYEVIVDTPIYLISDLCNTSNIDLPTYDMATTESSKVLPPTFEEATSVSASPRSSVSYYPDDISMQQLNLSRSTSLANGYLSTLHPKTTAVSDSSNGAPIRDQQEQQARPLRTEDYALQMGNENNAYSNMDGLLSQDIFEQETAATLFKRDIVTMNFNNNIFTPRYSPRTFTNTDYNYNDND-----------------------------------------NNDNDTEGPGPIIHPGPEPPRYDEISS-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53179-1", "uniprot_id": "PALF_YEAST", "id": "P53179-1", "name": "pH-response regulator protein palF/RIM8", "aln": "----------------------------------------MSLLRLWNKESRAPSKIKSHGIVGSYGNSMLAHNNVKQFRIDIDEPHRVWKPNESITGEAVIDIKRDITNVAIKLS--------LVCEVRVKTGN----------SPTSKNKRIEKTLEKS----------------------------------------------------------TFLYGQDYVKTAFSAKEKKPHVDKTTILNGLSK-----------------------------------------------------------------------------------------------GEHRFPFRIRIPRGRGMLSSIKFERGSITYFLSCTLESLNNINGLKKPEARCEREFAVIVPLD----VSRLPKPKTKTVVLQSASMVQNKKNKSTEDES--------------------------------------SSYTQLTQKSTTSNSSSSSVNSKTSPLPNKTVTISVD----------------------------------------------------IPQAGFMIGEIIPIDVKIDHYKPFYAPAG--------LTTTLVRICRVGG---------AGKDDPMETFRKDICQSISPIYINPETLQFQSRVYLKVP--------LDAFSTLTTVGKFFSFQYYIEVMVNLSKKNVVYTESNRIIGTPIGEQNGLGVEN-------------NINRIQRKMLRMVNPETLENDSEGYESSIFFKDMVN-----------VEKLKRLRNVTGMSIETVIGTTRSEQQQSDASIPSQSSITAPQNSPSNLRDWLAPLN-----------------------------------------------AYDSDDVPVPKYSPNDKVSVPSEDKQELEQKRLQQLESDPPPCDDY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : ", "identical_positions": 0, "similar_positions": 3, "identity": "0.0%" }, { "cls_id": "homologset.agr.RGD:620887", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K1I7-1", "uniprot_id": "WIPF1_MOUSE", "id": "Q8K1I7-1", "name": "WAS/WASL-interacting protein family member 1", "aln": "--MPVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILD----KPKGAGAS----------AGGYGGGGGGGGG-GGGGGGGSGGNFGG--GGP--PGLG---GLFQAGMP-------KLRSTANRD-----------------------------------NDSGGSRPPILPPG----GRA-------TSAKP-FSPPSGP---------GRFPAPSP----GHRSGPPEPPR---NRMPPPRPDVGSKPDSLPPPV--------PNTPR--------------------------------------------------------PVPSSLHNRGSPAGLGAPR------------PPFPGNRGAAFGAG----------SARQNPSGSSSPFP--------------------RPPLPPTPSR------ALDDKP-------PPPPPPVGNR---------------PSMHREAVPPPPSQTSKPPVPSTPRPGLGSQAPPP-----------------------------------------------------------------PPPPSRPGPPPLPPAS-----NDEIPRLPQRNLSLTSS--APPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGP-------------------------LPPPPPINRNGSTARALPATPQLPSRSGMDSPRSGPRPPLPPDRPGAGAP--PPPPPSTSVRNGFQDSS--CEDEWESRFYFHPIS----DLPPPEPYVPTTKTYPS------------------------------------------------KLARNESRSGSNRRERGAPPLPPIPR----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IN36-1", "uniprot_id": "WIPF1_RAT", "id": "Q6IN36-1", "name": "WAS/WASL-interacting protein family member 1", "aln": "--MPVPPPPAPPPPPTFALANTEKPSLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILD----KPKGAG-------------GGYGGGSGGGGG-GGSSGGG--GNFGG--GGP--PGLG---GLFQAGMP-------KLRSTANRD-----------------------------------NDSGGSRPPILPPG----GRA-------TSAKP-FSSPSGP---------GRFPAPSP----GHRSGPPEPPR---NRMPPPRPDVGSKPDSLPPPV--------PNTPR--------------------------------------------------------PIPSSLHNRGSPAGLGAPR------------PPFPGNRGAAFGAG----------SVRQNLSSSSSPFP--------------------RPPLPPTPSR------ALDDKP-------PPPPPPVGNR---------------PSMHREAVPPPPSQNSKPPVPSTPRPGAGSQAPPP-----------------------------------------------------------------PPP-SRPGPPPLPPTS-----SDEIPRLPQRNLSLTSP--TPPLPSPGRSGPLPPPPTERPPPPVRDPPGRSGP-------------------------LPPPPPINRNGSTARALPATPQLPSRSGMDSPRSGPRPPLPPDRPGAGAP--PPPPPSTSVRNGFQDSS--CEDEWESRFYFHPIS----DLPPPEPYVPTTKTYPS------------------------------------------------KVARSESRSGSNRRERGAPPLPPIPR----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43516-1", "uniprot_id": "WIPF1_HUMAN", "id": "O43516-1", "name": "WAS/WASL-interacting protein family member 1", "aln": "--MPVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILD----KPKGAG------------AGGGGGGFGGGGGFGGGGGGGGGGSFGG--GGP--PGLG---GLFQAGMP-------KLRSTANRD-----------------------------------NDSGGSRPPLLPPG----GRS-------TSAKP-FSPPSGP---------GRFPVPSP----GHRSGPPEPQR---NRMPPPRPDVGSKPDSIPPPV--------PSTPR--------------------------------------------------------PIQSSPHNRGSPPVPGGPRQPSP----GPTPPPFPGNRGTALGGG----------SIRQSPLSSSSPFSN-------------------RPPLPPTPSR------ALDDKP-------PPPPPPVGNR---------------PSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP-----------------------------------------------------------------PPPPSRPGPPPLPPSSS---GNDETPRLPQRNLSLSSS--TPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGP-------------------------LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAP--PPPPPSTSIRNGFQDSP--CEDEWESRFYFHPIS----DLPPPEPYVQTTKSYPS------------------------------------------------KLARNESRSGSNRRERGAPPLPPIPR----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QZL9-1", "uniprot_id": "F1QZL9_DANRE", "id": "F1QZL9-1", "name": "", "aln": "--MPGPPPPPPGPPPTFSQANTEKPNLSRNEQQGRNALLSDINKGARLKKTITNDRSGPVLD----KPKGGG---------------GGGGGGGGGGFGGGASGGMGGLFQG--GMPRLKSAGNRDGNVRAPMPPSGGRFPAPSSPAGRFPA--------------------------------PSSPAGSRPPVPGPGRPSPGRAGPPPIPSSSRSPQHSSPGGPPPIPGGRPQGSSPAPPPPNSSGRRTSFPQPPRESQSSFPPPPRESTFPPPPRESSF--------PPPPRE------------------------------------------------------SSFPPPPRESSFPPPPRESS-----------FPPPPRESHSSFPPP----------PRESQSSFPPPPIPASG-----------------RPPLPSIPGRP-----QADDFP-------PPPPPAGGRR---------------ESFCRDGPLPPPPPSTECKPMGSQRP--MGNAPPS-----------------------------------------------------------------LPP-GRGGAPPIPPSS-----RDELS---SRGASRNS---LPPPPPPGRTSPLPPPPSNERPPPTG-KSARSGS-------------------------LPPPPPAG--GNRGGAPPPVPP-PNRPGG----SG-RPSLVPDPPAPRVPSFPPAPPSDSIN-GYQCPPPPVSDEWGMRFSFHSLS----ELPPPEPYVSFSKSYPS------------------------------------------------KSG------GKGIKDRGAPPLPPIPR----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P37370-1", "uniprot_id": "VRP1_YEAST", "id": "P37370-1", "name": "Verprolin", "aln": "--MAGAPAPPPPPPPPALGGSAPKP--AKSVMQGRDALLGDIRKGMKLKKAETNDRSAPIVGGGVVSSASGSSG----------TVSSKGPSMSAPPIPGMGAPQLGDILAG--GIPKLKHINNNASTKPSPSASAPPIPGAVPSVAAPPIPNAPLSPAPA----------------------VPSIPSSSAPPIPDIP---SSAAPPIPIVPSSPAPPLPLSGASAPKVPQNRPHMPSVRPAHRSHQRKSSNISLPSVSAPPLPSASLPTHVSNPPQAPPP--------PPTPTIGLDSKNIKPTDNAVSPPSSEVPAGGLPFLAEINARRSERGAVEGVSSTKIQTENHKSPSQPPLPSSAPPIPTSHAPPL----PPTAPPPPSLPNVTSAPK----------KATSAPAPPPPPLPAAMSSASTNSVKATPVPPTLAPPLPNTTSVPPNKASSMPAPP-------PPPPPPPGAFSTSSALS-------ASSIPLAPLPPPPPPSVATSVPSAPPPPPTLTTNKPSASSKQSKISSSSSSSAVTPGGPLPFLAEIQKKRDDRFVVGGDTGYTTQDKQEDVIGSSKDDNVRPSPISPSINPPKQSSQNGMSFLDEIESKLHKQTSSNAF--NAPPPHTDAMAPPLPPSAPPPPITSLPTPTASGDDHTNDKSETVLGMKKAKAPALPGHVPPPPVPPVLSDDSKNNVPAASLLHDVLPSSNLEKPPSPPVAAAPPLPTFS--APSLPQQSVSTSIPSPPP-VAPTLSVRTETESISKNPTKSPPPPPSPSTMDTGTSNSPSKNLKQRLFSTGGSTLQHKHNTHTNQPDVDVGRYTIGGSNSIVGAKSGNERIVIDDSRFKWTNVSQMPKPRPFQNKTKLY--------PSGKGSSVPLDLTLFT-------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A8DYL3-1", "uniprot_id": "A8DYL3_DROME", "id": "A8DYL3-1", "name": "", "aln": "MAIPPPPGPPPPPGPPPPPAMGGLKLGGAGGADARSALLSSIQKGTKLKKTTTVDKSGPALSGKVCGGDGGAGIGAKRTLNNNTSTSNHNNSSSSSNGLGNGTPKLGGLFEGLSQMPKLKPVNGIRATPSAGSAATTTSKSTTNSSAQQRSNSPPAATSASNASNGPMDFNTELTKHLTLKRQKQQQQQQPQPPTNNTHIN-ATEANLRTNRGPPPQPPKSANSNDSILERMNIPRTAPTPPFGNSSSVKAASPTLSDSGSNSSGSGGGSGSVKSKAANLNISLGNSFVNSSKSTVSASTASLNSSLTSSTGSVRNLAPNKSTLFGGSSGSSSGSSSGGGYASVHKSSPPSTADSTPSVTPTPPPLQLPMKPAISFGKPNFAPKPPGLNQLAMANGQQRPAVTRHHSMKSPRSPPAAGIVNGLVFPTQQHLGTLRGPLQFHGSESSSPNTSAGSMRCAPNPPKSRPSVKPPPPPTPARSFSNTNLNNIGGSTMFSAVNTALIQSSAISSQAPSPPITQPPSSSSSSNSVAALRDQFRGGAGMSNG------------------------------------------------APSPPLPPTPAPSSNPSSASASPKSLLRDNVKPIILNGGPLNPPAPPPHRSCPPPPPPQRQSSNQDRVKYWIDKTVYSFKKILHINRQGRHS-----GESVKVINMLNSKRNGGSGSGSAPVPPQRHSSIRPNAPSTPPTHMANASHQFG--SSSGLSSGSGAGAAASVGRLVNDLETKFGKRFHN--VTEFPKPPPFLNIQKVYPSRTFKATN----------APGNSSVNNNNNAVASNNNTTSNPNPGGFGGGLAPVLKPAHAPLKKHRAPAPPPQAGVAAATVSVIRQSSFLYGGAAGGSSGSTSIRPQSQPPGIGPRNSTVY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .* *.* * *. . .*.***..* ** :***: * *:*.* :. ... . .. * . . : * * . . : . * * . . ** : .. * . . .. . ::. . . . . . .. . * * : . ... : . . .. * *****. . :. ... . : * : .* .* .. .. : .. .* * . * **. . . . ... . *. . ... . . . . : . . . * * * . .* . . . * . ", "identical_positions": 49, "similar_positions": 108, "identity": "5.33%" }, { "cls_id": "homologset.agr.RGD:620888", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JI85-1", "uniprot_id": "NUCB2_RAT", "id": "Q9JI85-1", "name": "Nucleobindin-2", "aln": "MRWRTIQARYCFLLVPCVLTALEAVPIDVDKTKVHNVEPVESARIEPPDTGLYYDEYLKQVIEVLETDPHFREKLQKADIEEIRSGRLSQELDLVSHKVRTRLDELKRQEVGRLRMLIKAKLDALQDTGMNHHLLLKQFEHLNHQNPDTFESKDLDMLIKAATADLEQYDRTRHEEFKKYEMMKEHERREYLKTLSEEKRKEEEAKFAEMKRKHEDHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNNDGFLDEQELEALFTKELDKVYNPQNAEDDMIEME----EERLRMREHVMNEIDNNKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEEELKEYES----------------------------------------------------------------------------------IIAIQESELKKKADEL---------------------------------------------QKQKEELQRQHDHLEAQK--QEYQQAVQQLEQKKFQQGIAPSGPAGELKFEPHT--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P81117-1", "uniprot_id": "NUCB2_MOUSE", "id": "P81117-1", "name": "Nucleobindin-2", "aln": "MRWRIIQVQYCFLLVPCMLTALEAVPIDVDKTKVHNTEPVENARIEPPDTGLYYDEYLKQVIEVLETDPHFREKLQKADIEEIRSGRLSQELDLVSHKVRTRLDELKRQEVGRLRMLIKAKLDALQDTGMNHHLLLKQFEHLNHQNPNTFESRDLDMLIKAATADLEQYDRTRHEEFKKYEMMKEHERREYLKTLSEEKRKEEESKFEEMKRKHEDHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNNDGFLDEQELEALFTRELEKVYNPQNAEDDMIEME----EERLRMREHVMSEIDNNKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEDELKEYES----------------------------------------------------------------------------------IIAIQENELKKRAEEL---------------------------------------------QKQKEDLQRQHDHLEAQK--QEYHQAVQHLEQKKLQQGIAPSGPAGELKFEPHT--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P80303-1", "uniprot_id": "NUCB2_HUMAN", "id": "P80303-1", "name": "Nucleobindin-2", "aln": "MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYLKQVIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLIKAKLDSLQDIGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEEFKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEME----EERLRMREHVMNEVDTNKDRLVTLEEFLKATEKKEFLEPDSWETLDQQQFFTEEELKEYEN----------------------------------------------------------------------------------IIALQENELKKKADEL---------------------------------------------QKQKEELQRQHDQLEAQK--LEYHQVIQQMEQKKLQQGIPPSGPAGELKFEPHI--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVK7-1", "uniprot_id": "NUCB_DROME", "id": "Q9VVK7-1", "name": "Nucleobindin", "aln": "MVQNVALLGLALIAISASIVALPVTQNKKDHKEAAESSTPATADVE---TALEYERYLREVVEALEADPEFRKKLDKAPEADIRSGKIAQELDYVNHHVRTKLDEIKRREVERLRELANQAYELSNDIDRKH---LKVSQHLDHDNEHTFEIEDLRKLIQKTSDDLAEADRKRRGEFKEYEMQKEFEREAQKKEMDEESRKKFETELKEKEEKHKDHEKLHHPGNKAQLEDVWEKQDHMDKNDFDPKTFFSIHDVDSNGYWDEAEVKALFVKELDKVYQSDLPEDDMRERA----EEMERMREHYFQETDMNHDGLISIDEFMVQTNKEEFQKDPEWETIDRQQQYTHEEYLEYERRRQEEVQRLIAQGQLPPHPNMPQGYYAAPPPGGVAYQQAPPGAQLHYQHPDQVHAQQQQQYAQQQQQYAQQYQQQQYGNGQQPVQLQPNQVYQHAGQIPQQQQPVYQNQPVYQQQQPVYQQQQPVQQQQKPVQQPVQQQQQPVQQQQQPVQQQQQTVQQQQPVQQQQQTVQQQQPVQQQQQTAQQQPVAQQQIHNQSPPPVLNQQVPVQQQQKQHQESLNQQH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39931-1", "uniprot_id": "SS120_YEAST", "id": "P39931-1", "name": "Protein SSP120", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MRFLRGFVFS-----------------------LAFTLYKVTATAEIGSEINVENEAP-------------------------PDGLSWEEWHMDHEHQLKDYTPETFFALHDIKKKGFLDENDILSLYGLNREEIVGAGDGMGQHDESEKIDNEMAKRVVSLIMRLLDVDDNTKITKEEYLQFAKRGNKFPDLGVGVGHHSDFELEYEIHHWNK----------------------------------------------------------------------------------FHKDKDPDVKVVHK-----------------------------------------------EDIEHELLHHEHEIEHEEEIQRGASRATVITDDELESRIELKNIPEKFKNGIF---------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . *. *. *:: * : .* . : *. . : :*: *:*** :**:...*: ** :: :*: : ::: . .: * * *: . : * :.: :: :*:: ::: : . .:.: . * .:: : :: :. :. : ::.. :: :: . . : :. . : : ", "identical_positions": 23, "similar_positions": 82, "identity": "3.97%" }, { "cls_id": "homologset.agr.RGD:620889", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJ09-1", "uniprot_id": "NPT2B_RAT", "id": "Q9JJ09-1", "name": "Sodium-dependent phosphate transport protein 2B", "aln": "MAPWPELENAHPNPNKFIEGASGPQSSIPDKDKGTSKTNDSGTPVAKIELLPSYSALVLIEEPPEGNDPWDLPELQDNGIKWSERDSKGKILCIFQGIGKFILLLGFLYLFVCSLDVLSSAFQLVGGKMAGQFFSNNSIMSNPVAGLVIGVLVTVMVQSSSTSSSIIVSMVASSLLSVRAAIPIIMGANIGTSITNTIVALMQAGDRNEFRRAFAGATVHDFFNWLSVLVLLPLEAATHYLEKLTNLVLETFSFQNGEDAPDILKVITDPFTKLIIQLDKKVIQQIAMGDSEAQNKSLIKIWCKTISNVIEENVTVPSPDNCTSPSYCWTDGIQTWTIQNVTEKENIAKCQHIFVNFSLPDLAVGIILLTVSLLILCGCLIMIVKLLGSVLRGQVATVIKKTLNTDFPFPFAWLTGYLAILVGAGMTFIVQSSSVFTSAMTPLIGIGVISIERAYPLTLGSNIGTTTTAILAALASPGNTLRSSLQIALCHFFFNISGILLWYPIPFTRLPIRLAKGLGNISAKYRWFAVFYLIFFFLLTPLTVFGLSLAGWPVLVGVGVPIILLILLVLCLRMLQARCPRILPLKLRDWNFLPLWMHSLKPWDNIISLATSCFQRRCCCCCRVCCRVCCMVCGC-KCCRCSKCCKN--LEEEEKEQDVPVKASGGFDNTAMSKECQDEGKGQVEVLGMKALSNTTVF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBP0-1", "uniprot_id": "NPT2B_MOUSE", "id": "Q9DBP0-1", "name": "Sodium-dependent phosphate transport protein 2B", "aln": "MAPWPELENAQPNPGKFIEGASGPQSSIPAKDKEASKTNDNGTPVAKTELLPSYSALVLIEEHPEGTDPWDLPELQDTGIKWSERDTKGKTLCIFQGVGKFILLLGFLYLFVCSLDVLSSAFQLVGGKVAGQFFSNNSIMSNPVAGLVIGVLVTVMVQSSSTSSSIIVSMVASSLLTVRAAIPIIMGANIGTSITNTIVALMQAGDRNEFRRAFAGATVHDFFNWLSVFVLLPLEAATHYLEILTNLVLETFKFQNGEDAPDILKVITDPFTKLIIQLDKKVIQQIAMGDSAAQNKSLIKIWCKSITNVTEMNVTVPSTDNCTSPSYCWTDGIQTWTIQNVTQKENIAKCQHIFVNFSLPDLAVGIILLTVSLVVLCGCLIMIVKLLGSVLRGQVATVIKKTLNTDFPFPFAWLTGYLAILVGAGMTFIVQSSSVFTSAMTPLIGIGVISIERAYPLTLGSNIGTTTTAILAALASPGNTLRSSLQIALCHFFFNISGILLWYPIPFTRLPIRLAKGLGNISAKYRWFAVFYLIFFFFVTPLTVFGLSLAGWPVLVGVGVPIILLLLLVLCLRMLQFRCPRILPLKLRDWNFLPLWMHSLKPWDNVISLATTCFQRRCCCCCRVCCRVCCMVCGC-KCCRCSKCCRDQGEEEEEKEQDIPVKASGAFDNAAMSKECQDEGKGQVEVLSMKALSNTTVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95436-1", "uniprot_id": "NPT2B_HUMAN", "id": "O95436-1", "name": "Sodium-dependent phosphate transport protein 2B", "aln": "MAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTLQDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTSIVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFKNGEDAPDLLKVITKPFTKLIVQLDKKVISQIAMNDEKAKNKSLVKIWCKTFTNKTQINVTVPSTANCTSPSLCWTDGIQNWTMKNVTYKENIAKCQHIFVNFHLPDLAVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRSSLQIALCHFFFNISGILLWYPIPFTRLPIRMAKGLGNISAKYRWFAVFYLIIFFFLIPLTVFGLSLAGWRVLVGVGVPVVFIIILVLCLRLLQSRCPRVLPKKLQNWNFLPLWMRSLKPWDAVVSKFTGCFQMRCCCCCRVCCRACCLLCDCPKCCRCSKCCED--LEEAQEGQDVPVKAPETFDNITISREAQG------EVPASDSKTECTAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P515-1", "uniprot_id": "A0A8M9P515_DANRE", "id": "A0A8M9P515-1", "name": "Sodium-dependent phosphate transport protein 2B", "aln": "MAPLAETHPASPPP-------------------ELGADADKHEPQTPTRTLSPWPAQQWEPEQEEEVDPWELPELLDTGVKWSELDRRGKVLRVCTSVLKLLLLLGLLYMFVCSLDILSSAFQLVGGKAAGDIFKDNAVLSNPVAGLVIGVLVTVLVQSSSTSSSIVVSMVSSGLLEVKSAVPIIMGANIGTSVTNTIVAVMQAGDRNEFRRAFAGATVHDFFNWLSVLVLLPLEVASGMLYRLTKLVIDSFNIQTGADAPDLLKVITEPLTKNIIELDTSVIRDIATGDPAARNKSLIKIWCKTEKITNLVNVTVPGIANCTPDALCWVDGDLIWTQKNQTDTIYLKKCTHMFVFADLPDLAVGLILLALSLLALCTCLILIVKLLNSMLKGQVAVVIKKVLNTDFPFPFAWVTGYLAILVGAGMTFIVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTAILAAMASPGETLANSLQISLCHFFFNIAGILLWYPIPFTRVPIRLAKALGNRTAKYRWFAGLYLILCFLLFPLTVLGLSIAGWQVLVGVGVPVLVLAIFVIVVNVMQKRCPRFLPSFIRSWEFLPKPLHSLKPWDRVVTAGMSFCRTRCCCCC--------------------KCCRN----EEKNHVENNDRSLEMYDNPALAIEDEA------KVTATHL-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** .* * * * . :. * : . *..:.: * * ***:** * *.*:**** * :** * . .: :::****:**:******:*********** **::*.:.:::***: **********:*******:**:****:*.** *::*:***********:******:**.***.********************:****:*.*: * :*:*::::* ::.* ****:*****.*:** *::**..** :** .* *:****:*****: . *****. ***. : **.** ** :* * . : ** *:** ******* *** :**: ** ***:***:*.*:*:****.****.:**********:*************************:***:*****::**********************:****::* .****:********:************:***:**.*** :******* :***: *:: ****:***:*** ********::.: ::*: :.::* ****.** ::.*:*** ::****** ::: : ****** ***.: * :: : :: :** ::: * : :* . . ", "identical_positions": 382, "similar_positions": 147, "identity": "54.73%" }, { "cls_id": "homologset.agr.RGD:620890", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51156-1", "uniprot_id": "RAB26_RAT", "id": "P51156-1", "name": "Ras-related protein Rab-26", "aln": "MSRKKTPKSKG------GSVPAASTLPAAA---NGPRLAHPRTARP------------GPEAPPNGPP---------------QSGRP-----------------------SLGGTGDFYD-------------------------------------------------------------------VAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGMKVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDITNKDSFDNIQAWLTEIQEYAQQDVVLMLLGNKVDST-QERVVKREDGEKLAKEYGLPFMETSAKSGLNVDLAFTAIAKELKQRSTKAPSEPRFRLHDYVKREGRGVSCCRL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q504M8-1", "uniprot_id": "RAB26_MOUSE", "id": "Q504M8-1", "name": "Ras-related protein Rab-26", "aln": "MSRKKTPKSKG------GSEPATSTLPAAAAATNGPRLAHPRTVRP------------GPEAPPNGPP---------------QSIRP-----------------------SLGSTGDFYD-------------------------------------------------------------------VAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGMKVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDITNKDSFDNIQAWLTEIQEYAQQDVVLMLLGNKVDST-QDRVVKREDGEKLAKEYGLPFMETSARTGLNVDLAFTAIAKELKQRSAKAPSEPRFRLHDYVKREGRGVSCCRL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULW5-1", "uniprot_id": "RAB26_HUMAN", "id": "Q9ULW5-1", "name": "Ras-related protein Rab-26", "aln": "MSRKKTPKSKG------ASTPAASTLPTAN----GARPARSGTALS------------GPDAPPNGPL---------------QPGRP-----------------------SLGGGVDFYD-------------------------------------------------------------------VAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGVKVKLQMWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKASFDNIQAWLTEIHEYAQHDVALMLLGNKVDSA-HERVVKREDGEKLAKEYGLPFMETSAKTGLNVDLAFTAIAKELKQRSMKAPSEPRFRLHDYVKREGRGASCCRP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VP48-1", "uniprot_id": "RAB26_DROME", "id": "Q9VP48-1", "name": "Ras-related protein Rab-26", "aln": "MASTAVGLGGGEGDPGAGGPPAGSAHPDDASSMSDDVFEDAETTQARIEELRRRPFGDGSYNPPAAPASVSASITTTTTQQQQQHHNPSHHHQSSHHQPSHHHHHHHHSQLSLTGSHHYHDDAIMAPVQRSATGYPGYRPSREAMQMYAYGTDDYDDDYNDGWRSYRYDEVDMHPAPSNAHQQPFDDTVNHKTILLGDSGVGKTSFLVKYNTGEFRLGSFSATVGIALTNKVVVVDGTRVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKTTYDNIRAWLGEIREYAQEDVVIVLIGNKADCSGSERQVKREDGERLGREHNVPFMETSAKTGLNVELSFTAVARQLKSRGYEHGDDGKFNVHDFVRDNTKARSVCAQCRNM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . . . * .. ** *: * . . *. . *. ** .* * .* ** . .::* * .*.:*:********.:**::: * * *:* :**** : ***: *** :****:****************************:*** ::***:*** **:****.**.::*:***.*.: :* *******:*.:*:.:*******::****:*:***:*::**.*. : .: :*.:**:*: : :. * * ", "identical_positions": 132, "similar_positions": 73, "identity": "34.02%" }, { "cls_id": "homologset.agr.RGD:620891", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51158-1", "uniprot_id": "RAB28_RAT", "id": "P51158-1", "name": "Ras-related protein Rab-28", "aln": "MSDSEEESQDRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMRTVKPDKHLRFCQENGFSSHFVSAKTGDSVFLCFQKVAAEILGIKLNKAEIEQSQRVVKADIVNYNQEPMSRTVNPPRSSMCAVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KL7-1", "uniprot_id": "RAB28_MOUSE", "id": "Q99KL7-1", "name": "Ras-related protein Rab-28", "aln": "MSDSEEESQDRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMRTVKADKHLRFCQENGFSSHFVSAKTGDSVFLCFQKVAAEILGIKLNKAEIEQSQRVVKADIVNYNQEPLSRTVNPPRSSMCAVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51157-1", "uniprot_id": "RAB28_HUMAN", "id": "P51157-1", "name": "Ras-related protein Rab-28", "aln": "MSDSEEESQDRQLKIVVLGDGASGKTSLTTCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQIWDIGGQTIGGKMLDKYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVGNKIDLEHMRTIKPEKHLRFCQENGFSSHFVSAKTGDSVFLCFQKVAAEILGIKLNKAEIEQSQRVVKADIVNYNQEPMSRTVNPPRSSMCAVQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********************:******:************************************:**********************:*******************:***.*************************:*.:***************************************************************:***************", "identical_positions": 211, "similar_positions": 10, "identity": "95.48%" }, { "cls_id": "homologset.agr.RGD:620892", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91YQ1-1", "uniprot_id": "RAB7L_MOUSE", "id": "Q91YQ1-1", "name": "Ras-related protein Rab-29", "aln": "MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDSEMVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPSGEPVPCLLLANKSDLSPWAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLVEKMMNNSREDVMSLSTQGNYINLQAKPSSGWTCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63481-1", "uniprot_id": "RAB7L_RAT", "id": "Q63481-1", "name": "Ras-related protein Rab-29", "aln": "MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDSEMVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPSGEPVPCLLLANKSDLSPWAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLVEKMMNNSREDIMSSSTQGNYINLQTKPSPGWTCC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14966-1", "uniprot_id": "RAB7L_HUMAN", "id": "O14966-1", "name": "Ras-related protein Rab-29", "aln": "MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDYEIVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGEPVPCLLLANKCDLSPWAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMMRNSTEDIMSLSTQGDYINLQTKSSS-WSCC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************************************** *:*********************************************************.************.******************************************:****.** **:** ****:*****:*.*. *:**", "identical_positions": 189, "similar_positions": 11, "identity": "92.65%" }, { "cls_id": "homologset.agr.RGD:620893", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BRK8-1", "uniprot_id": "AAPK2_MOUSE", "id": "Q8BRK8-1", "name": "5'-AMP-activated protein kinase catalytic subunit alpha-2", "aln": "------------MAEKQKHD---------------------------GRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPDYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDP------------------SYDANVIDDEAVKEVCEKFECTESEVMNSLYSGD---PQDQLAVAYHLIIDNRRIMNQAS---------EFYLASSPPS-------------------------GSFMDDSAMHIPPG----------LKPHPER-----MPPL----IADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKACDIMAEVYRAMKQLGFEWKVVN---AYHLRVRRK---------NPVTGNYVKMSLQLYLVDSRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRARSSFDSSTAENHSLSGSLTGSLTGSTLSSASPRLGSHTMDFFEMCASLITALAR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09137-1", "uniprot_id": "AAPK2_RAT", "id": "Q09137-1", "name": "5'-AMP-activated protein kinase catalytic subunit alpha-2", "aln": "------------MAEKQKHD---------------------------GRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDP------------------SYDANVIDDEAVKEVCEKFECTESEVMNSLYSGD---PQDQLAVAYHLIIDNRRIMNQAS---------EFYLASSPPT-------------------------GSFMDDMAMHIPPG----------LKPHPER-----MPPL----IADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVN---AYHLRVRRK---------NPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRPRSSVDSSTAENHSLSGSLTGSLTGSTLSSASPRLGSHTMDFFEMCASLITALAR-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54646-1", "uniprot_id": "AAPK2_HUMAN", "id": "P54646-1", "name": "5'-AMP-activated protein kinase catalytic subunit alpha-2", "aln": "------------MAEKQKHD---------------------------GRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDP------------------SYDANVIDDEAVKEVCEKFECTESEVMNSLYSGD---PQDQLAVAYHLIIDNRRIMNQAS---------EFYLASSPPS-------------------------GSFMDDSAMHIPPG----------LKPHPER-----MPPL----IADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVN---AYHLRVRRK---------NPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFFEMCASLITTLAR-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O18645-1", "uniprot_id": "O18645_DROME", "id": "O18645-1", "name": "non-specific serine/threonine protein kinase", "aln": "MPQMRAAAAEAVAAGSANGQ---------------------------PLVKIGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDLPAYLFPSSI------------------EQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGD---PHDQLAIAYHLIIDNKRFADDAAN--QINEINNFFVAGSPPPPPPPPVPQSSMDHQAPLATVTVGGGTSASSGTATPVPPVAGGTPSSTIPIRPHPER-----IAPMRDRQLAMSVQTSGGGAFPEKTARGGTPIKRAKWHLGIRSQSKPNDIMLEVYRAMKALSYEWKIIN---PYHVRVRRQ---------NVKTGKFSKMSLQLYQVDAKSYLLDFKSLTNDEVEQGDD-----------------VIMESLTPPPLSVSGVMPLQPTG-----------HHTMEFFEMCAALIIQLAR-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06782-1", "uniprot_id": "SNF1_YEAST", "id": "P06782-1", "name": "Carbon catabolite-derepressing protein kinase", "aln": "MSSNNNTNTAPANANSSHHHHHHHHHHHHHGHGGSNSTLNNPKSSLADGAHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVDLPEYLLPPDLKPHPEEENENNDSKKDGSSPDNDEIDDNLVNILSSTMGYEKDEIYESLESSEDTPAFNEIRDAYMLIKENKSLIKDMKANKSVSDELDTFLSQSPPTFQQQSKSHQKSQVDHETAKQHARRMASAITQQRTYHQSP---------FMDQYKEEDSTVSILPTSLPQIHRANMLAQGSPAASKISPLVTKKSKTRWHFGIRSRSYPLDVMGEIYIALKNLGAEWAKPSEEDLWTIKLRWKYDIGNKTNTNEKIPDLMKMVIQLFQIETNNYLVDFK-FDGWESSYGDD-----------------TTVSNISEDEMSTFSAYP---------------------FLHLTTKLIMELAVNSQSN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : . .:**:* : *** *:*****:. * * ***:**:*:: : . *: *:*.***. *:*:*********:**.: :::*::**. *.****** ::.::.* :***:****:*.*:***** :*********:*** :::.*********:* **:**:****************:********:********.:** ****** :*.**::* .*:: :*.:*. . *: :** *:**:* .*.:* :.:**: *** **:* . . * : ** * :. .: : *: :** *.: . ::: ** ** :*: : .: : ::: ***. * . : : *. : * : : .. .:::**:****:* . *:* *:* *:* *. ** . : :::* : * . ** :**: :: ..**:*** : . . .. ... : * . . *:.: : ** ** ", "identical_positions": 207, "similar_positions": 155, "identity": "30.35%" }, { "cls_id": "homologset.agr.RGD:620894", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35831-1", "uniprot_id": "PTN12_MOUSE", "id": "P35831-1", "name": "Tyrosine-protein phosphatase non-receptor type 12", "aln": "MEQVEILRRFIQRVQAMKSPDHNGEDNFARDFMR-LRRLSTKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPS--QDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYN---VVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCENEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADG-NEITTGTMVSSIDSEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDSDRYHPKPVLHMASPEQHPADLNRSYDKSADPMGKSESAIEHIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASSSVVDRTSKPQELSAGALKVDDVSQNSCADCSAAHSHRAAESSEESQSNSHTPPRPDCLPLDKKGHVTWSLHGPENATPVPDSPDGKSPDNHSQTLKTVSSTPNSTAEEEAHDLTEHHNSSPLLKAPLSFTNPLHSDDSDSDGGSSDGAVTRNKTSISTASATVSPASSAESACTRRVLPMSIARQEVAGTPHSGAEKDADVSEESPPPLPERTPESFVLA---DMPVRPEWHELPNQEWSEQRESEGLTTSGNEK--HDAGGIHTEASADSPPAFSDKKDQITKSPAEVTDIGFGNRCGKPKGPREPPSEWT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZN71-1", "uniprot_id": "A0A8I5ZN71_RAT", "id": "A0A8I5ZN71-1", "name": "Tyrosine-protein phosphatase non-receptor type 12", "aln": "MEQVEILRRFIQRVQAMKSPDHNGEDNFARDFMR-LRRLSTKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPS--QDSDYINANFIKGVYGPRAYVATQGPLANTVIDFWRMIWEYN---VVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISC---VICTYILLLTECLFFMKESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKITDG-NEISTGNMVSSIDSEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDSDRYHPKPVLHMASPEQPPTDLNRNYDKSADLMGRSESAVEHTDKKLEQNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASSSVVDKSSKPQELSSGDLKVHDVSQNSCADCSASHLDNAPESSEESQ-NSHTPPRPDCLPLDKKGHVTWSLHGPENATPVSDSPD-----NHSQTLKTVSSTPNSTAEEESHDLTEHHNSSPLPRAPLSFTNPLHSDDSDSDEGNSDGAVTKNKTSISTASATVSPASSTESACTRRVLPMSIARQEMAGRRHSGAEKDADVSEESPPPLPERTPESFVLA---DMPIRSDWHELPSQECSEHRESEGLITSGNDK--HDAGVSHTAACS---PTFSDKKEEITESLTEVTDIGFGNRCGKPKGPRDPPSEWT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05209-1", "uniprot_id": "PTN12_HUMAN", "id": "Q05209-1", "name": "Tyrosine-protein phosphatase non-receptor type 12", "aln": "MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMR-LRRLSTKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPS--QDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYN---VVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQELSS-DLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25044-1", "uniprot_id": "PTP1_YEAST", "id": "P25044-1", "name": "Tyrosine-protein phosphatase 1", "aln": "---MAAAPWYIR----QRDTDLLGKFKFIQNQEDGRLREATNGTVNSRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSGNDYINASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVD---------------------------------------------------------DTVRIASKWES-----------PGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNS----------------------RGNPIIVHCSAG---------------------VGRTGTFIALDHLMHDT----------------------LDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMK---------MVQTKDQFLFIYHAAKYLNSLSVNQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*: :..* *: :* :: * :*: .:. :. ... : .* :*** :*:*:::.**:*. : . ::.*::.*. * *:***** :* :**:* :. ::***. .* .*:** :*** * * * : : *::. .* .. : . * . ::::. *: : :.* :: ..*:* .:: : : *: : : *: . .: :. * * . . ..:* :: : :*. .:.: :: :.: : *. :.* .:: ::::. :: : .:.: : * *: : . : ", "identical_positions": 58, "similar_positions": 135, "identity": "7.37%" }, { "cls_id": "homologset.agr.RGD:620895", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75310-1", "uniprot_id": "UDB11_HUMAN", "id": "O75310-1", "name": "UDP-glucuronosyltransferase 2B11", "aln": "----------MTLKWTSVLLLIHLSCYFSSGSCGKVLVWAAEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPNDASTLKFEVYPTSLTKTEFENIIMQQVKRWS-DIRKDSFWLYFSQEQEILWELYDIFRNFCKDVVSNKKVMKKLQESRFDIVFADAVFPCGELLAALLNIRFVYSLRFTPGYTIERHSGGLIFPPSYIPIVMS--KLSDQMTFMERVKNMIYVLYFDFWFQMSDMKKWDQFYSEVLG-----RPTTLFETMGKADIWLMRNSWSFQFPHPFLPNVDFVGGFHCKPAK---PLPKEMEEFVQSSGENGVVVFSLGSVISN--MTAERANVIATALAKIPQKVLWRFDGNKPDA-LGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRLDFNTMSSTDLLNALKTVINDPLYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMPHK--GAKHLRVAAHDLTWFQYHSLDVIGFLLACVATVIFIITKFCLFCFW------KFARKGK------KGKRD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BY64-1", "uniprot_id": "UDB28_HUMAN", "id": "Q9BY64-1", "name": "UDP-glucuronosyltransferase 2B28", "aln": "----------MALKWTSVLLLIHLGCYFSSGSCGKVLVWTGEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPNDAFTLKLEVYPTSLTKTEFENIIMQQVKRWS-DIQKDSFWLYFSQEQEILWEFHDIFRNFCKDVVSNKKVMKKLQESRFDIIFADAFFPCGELLAALLNIPFVYSLCFTPGYTIERHSGGLIFPPSYIPVVMS--KLSDQMTFMERVKNMIYVLYFDFWFQMCDMKKWDQFYSEVLG-----RPTTLFETMGKADIWLMRNSWSFQFPHPFLPNIDFVGGLHCKPAK---PLPKEMEEFVQSSGENGVVVFSLGSVISN--MTAERANVIATALAKIPQKVLWRFDGNKPDA-LGLNTRLYKWIPQNDLLGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLDFHTMSSTDLLNALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAVFWIEFVMCHK--GAKHLRVAARDLTWFQYHSLDVIGFLLACVATVIFVVTKFCLFCFW------KFARKGK------KGKRD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36537-1", "uniprot_id": "UDB10_HUMAN", "id": "P36537-1", "name": "UDP-glucuronosyltransferase 2B10", "aln": "----------MALKWT-TVLLIQLSFYFSSGSCGKVLVWAAEYSLWMNMKTILKELVQRGHEVTVLASSASILFDPNDSSTLKLEVYPTSLTKTEFENIIMQLVKRLS-EIQKDTFWLPFSQEQEILWAINDIIRNFCKDVVSNKKLMKKLQESRFDIVFADAYLPCGELLAELFNIPFVYSHSFSPGYSFERHSGGFIFPPSYVPVVMS--KLSDQMTFMERVKNMLYVLYFDFWFQIFNMKKWDQFYSEVLG-----RPTTLSETMRKADIWLMRNSWNFKFPHPFLPNVDFVGGLHCKPAK---PLPKEMEEFVQSSGENGVVVFSLGSMVSN--MTEERANVIATALAKIPQKVLWRFDGNKPDA-LGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRVDFNTMSSTDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHNLTWFQYHSLDVIGFLLACVATVLFIITKCCLFCFW------KFARKGK------KGKRD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16662-1", "uniprot_id": "UD2B7_HUMAN", "id": "P16662-1", "name": "UDP-glucuronosyltransferase 2B7", "aln": "----------MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWS-DLPKDTFWLYFSQVQEIMSIFGDITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTFEKHSGGFIFPPSYVPVVMS--ELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVLG-----RPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCKPAK---PLPKEMEDFVQSSGENGVVVFSLGSMVSN--MTEERANVIASALAQIPQKVLWRFDGNKPDT-LGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFW------KFARKAK------KGKND----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06133-1", "uniprot_id": "UD2B4_HUMAN", "id": "P06133-1", "name": "UDP-glucuronosyltransferase 2B4", "aln": "----------MSMKWTSALLLIQLSCYFSSGSCGKVLVWPTEFSHWMNIKTILDELVQRGHEVTVLASSASISFDPNSPSTLKFEVYPVSLTKTEFEDIIKQLVKRWA-ELPKDTFWSYFSQVQEIMWTFNDILRKFCKDIVSNKKLMKKLQESRFDVVLADAVFPFGELLAELLKIPFVYSLRFSPGYAIEKHSGGLLFPPSYVPVVMS--ELSDQMTFIERVKNMIYVLYFEFWFQIFDMKKWDQFYSEVLG-----RPTTLSETMAKADIWLIRNYWDFQFPHPLLPNVEFVGGLHCKPAK---PLPKEMEEFVQSSGENGVVVFSLGSMVSN--TSEERANVIASALAKIPQKVLWRFDGNKPDT-LGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGVPLFADQPDNIAHMKAKGAAVSLDFHTMSSTDLLNALKTVINDPLYKENAMKLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHDLTWFQYHSLDVTGFLLACVATVIFIITK-CLFCVW------KFVRTGK------KGKRD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54855-1", "uniprot_id": "UDB15_HUMAN", "id": "P54855-1", "name": "UDP-glucuronosyltransferase 2B15", "aln": "----------MSLKWTSVFLLIQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVTVLTSSASTLVNASKSSAIKLEVYPTSLTKNYLEDSLLKILDRWIYGVSKNTFWSYFSQLQELCWEYYDYSNKLCKDAVLNKKLMMKLQESKFDVILADALNPCGELLAELFNIPFLYSLRFSVGYTFEKNGGGFLFPPSYVPVVMS--ELSDQMIFMERIKNMIHMLYFDFWFQIYDLKKWDQFYSEVLG-----RPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPAK---PLPKEMEEFVQSSGENGIVVFSLGSMISN--MSEESANMIASALAQIPQKVLWRFDGKKPNT-LGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPVYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHK--GAKHLRVAAHNLTWIQYHSLDVIAFLLACVATVIFIITKFCLFCFR------KLAKKGK------KKKRD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O75795-1", "uniprot_id": "UDB17_HUMAN", "id": "O75795-1", "name": "UDP-glucuronosyltransferase 2B17", "aln": "----------MSLKWMSVFLLMQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVIVLTSSASILVNASKSSAIKLEVYPTSLTKNDLEDFFMKMFDRWTYSISKNTFWSYFSQLQELCWEYSDYNIKLCEDAVLNKKLMRKLQESKFDVLLADAVNPCGELLAELLNIPFLYSLRFSVGYTVEKNGGGFLFPPSYVPVVMS--ELSDQMIFMERIKNMIYMLYFDFWFQAYDLKKWDQFYSEVLG-----RPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPAK---PLPKEMEEFVQSSGENGIVVFSLGSMISN--MSEESANMIASALAQIPQKVLWRFDGKKPNT-LGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPIYKENIMKLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHNLTWIQYHSLDVIAFLLACVATMIFMITKCCLFCFR------KLAKTGK------KKKRD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36511-1", "uniprot_id": "UDB15_RAT", "id": "P36511-1", "name": "UDP-glucuronosyltransferase 2B15", "aln": "----------MSGKWISALLLLQISFCFKSGNCGKVLVWPMEYSHWMNIKIILEELVQKGHEVTVLRPSAFVFLDPKETSDLKFVTFPTSFSSHDLENFFTRFVNVWTYELPRDTCLSYFLYLQDTIDEYSDYCLTVCKEAVSNKQFMTKLQESKFDVVFSDAIGPCGELIAELLQIPFLYSLRFSPGYTIEQYIGGVLFPPSYVPMIFS--GLAGQMTFIERVHNMICMLYFDFWFQTFREKKWDPFYSKTLG-----RPTTLAEIMGKAEMWLIRSYWDLEFPHPISPNVDYIGGLHCKPAK---PLPKDIEDFVQSSGEHGVVVFSLGSMVRN--MTEEKANIIAWALAQIPQKVLWRFDGKKPPT-LGPNTRLYKWLPQNDLLGHPKTKAFVTHGGANGIYEAIHHGIPMIGIPLFAEQHDNIAHMVAKGAAVEVNFRTMSKSDLLNALEEVIDNPFYKKNAMWLSTIHHDQPTKPLDRAVFWIEFVMRHK--GAKHLRSLGHNLPWYQYHSLDVIGFLLSCVAVTVVLALKCFLFVYR------FFVKKEK------KTKNE----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B8JMA2-1", "uniprot_id": "B8JMA2_DANRE", "id": "B8JMA2-1", "name": "UDP-glucuronosyltransferase", "aln": "------------MTSGALLVCLLLCGVDVGWSG-RVLVMPGEYSHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKERFEYHVFKVNMEKEEADAAMRDMIHLFTNDTAAK--YEGEFVMWKVMSKFVEFGDVYFRGLFD-VGLLKTLRDSNYDVLFSDPMMPFSDLMAQKLNIPQVISMRATFAYAAERLCGQMPAPPSYVPAVALTDHLTDRMSFMERVENMLLYIVHSIAFPLVATFTFDGYYSEILG-----KPTTMCETMGKVDICLIRTYWDFEYPRPFPPNFKFVGGLHCKPAK---PLSKELEEFVQSSGDHGVVVFSLGSMIKN--LTSERANTIAAALGQIPQKVVWRYSGKTPET-LAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLLHIKTKGAAVVLDIHTMGSKDLVDALKAVVNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNK--GAKHLRVQAHELSWYQYHCLDVAAFLLSITALITFLWVKACCFLFR------RCVRKTRPERKRQKNKKE----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NX95-1", "uniprot_id": "A0A8M1NX95_DANRE", "id": "A0A8M1NX95-1", "name": "glucuronosyltransferase", "aln": "-------MSPRGSTGVFLLLALLLNQNLLCVSGGKILVWPAEFSHWLNIKVILDVLIERGHNITVVTHTATPSVQTTPSAGYNAEILQVPYTKQEIVDNLERMLKYWTHDLPNDNIITASLKIHEMITTATAQNKITCNALFSRADLLEKWKMEKFDVILADPLYICGEILAQKLDIPLIFSLRFTFGNTLERLCGQMPAPPSYVPAVAS--EKTDQMDFIDRLKNFLFYGMQDFLFYLVTKFKWDHYYSEVLG-----KPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHCKPAK---PLSKEMEEFVQSSGDHGVVVFSLGSMIKN--LTSERANTIAAALGQIPQKVVWRYSGKTPET-LAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNK--GAKHLRVQAHELSWYQYHCLDVAAFLLSIAALITFLWVKACCFLFR------RCVRKTRPERKTQKSKNE----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2J3-1", "uniprot_id": "Q9W2J3_DROME", "id": "Q9W2J3-1", "name": "UDP-glucuronosyltransferase", "aln": "-------MQFPLLFGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVTAFSLEKEQLGSNYTEILIEPVYDF-------WHDVKLNFGAQHLFELTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLITPWSFVPHGFM--PFTDRMSFLERVKNSYASFYEDMDRLLNYFPKMDAVAREFFG-PVLTEVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPVGGMHIYPPK---PLPADMQALLDGA-TEGAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFEDESISQ-LPDNVMVRKWLPQADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHR--GASHMRSAGLDLNWFQFYLLDVIAFVAIIALAGVMALSLAIR------------LLMG-SNKKHRKAKQN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ81-1", "uniprot_id": "Q9VJ81_DROME", "id": "Q9VJ81-1", "name": "UDP-glucuronosyltransferase", "aln": "-------MEMQLQWKCWMLIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHP--HENLTEIIISPSF-----------DIPKHFPKENIFSMQFVSDFNNLELWWTIGLMTTEHAFKDPKVKKLIES--KDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLL--SHTDRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPK---QLPTDLQNFLDNA-TYGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGD-LPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHR--GARHLKSHGAFIPLHQYLLLDVLGCLLLGAFLAIWLPWRMIRR-------VHKWWLKGESSNKLNEGKKRL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS9-1", "uniprot_id": "Q9VGS9_DROME", "id": "Q9VGS9-1", "name": "", "aln": "MGGIFSVTGLGILLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGSDKNEPNFRVIGAKKIHEI--------------MAAFGNADYTQTAS-QWQMLTMTTQFLNLLTTSILDDAAVKD-LLN-SG-EKFDLVIMEAVQTEALFGLIQHFGAETIGISSYGTDTHIDELMGNISPLSYNPLLLS--SRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFP--TARK--SLDEVLDSFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQS-EKGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPE-KPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHK--GAKHLRCASRDLDFIQFHGLDTWGLLIAITFVSLLIVVILIKCLQRVFVSLISKIRK--NRAEASKLKTQ----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT8-1", "uniprot_id": "Q9VGT8_DROME", "id": "Q9VGT8-1", "name": "UDP-glucuronosyltransferase", "aln": "------MRLLTVIAIVFCALSAKPLES--ESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVINAFK-NKETPNMRFIEALKAHEF--------------ADEM--MSLLNVPL-LWQQLNAMDYILNKFIDVTMEDEGVQR-LLN-SG-ETFDLVLAEMLHMEPMYAFAQHFNATLVGFSSFGTDRTIDEAAGNISPISYNPLVTS--PRTDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKKYFP--NAKK--TLEEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISHKP--KPLPEDIKQFIEGS-PHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPG-KPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHN--GAPHLRATSRDLNFIQLNSLDTLAVILAVPLLLALLIVTLS-------CKLLGGKKQ--KCLHADKLKKH----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT0-1", "uniprot_id": "Q9VGT0_DROME", "id": "Q9VGT0-1", "name": "UDP-glucuronosyltransferase", "aln": "---------MLALRIGFLLLTLP---ASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNAFPQKKPVVNFRDVFIPDVFNN--------------YKEL-INELSGPMN-LWQENNFINKFFVSVTRCVLTNKEVTETLLP-PGKDHFDLIIVEALRSDAYYGFAAHFNAPIIGISTFGTDWNIDALVGNESPLSYTPLATG--GLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFP--EASKRVQLTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKP--APLPKDLEEFIQGSGEHGVIYFSLGSNVLSKDLPADRKDLILKTFASLPQRVLWKFEDDKLPG-KPSNVFISKWFPQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHK--GAYHMRVAGQDLGFFAYHSLDVIGVLLGGALLLVAIIVGVL-----------GKLTD--FGNAKKKLKSK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT4-1", "uniprot_id": "Q9VGT4_DROME", "id": "Q9VGT4-1", "name": "UDP-glucuronosyltransferase", "aln": "---------MRWLLNSWLLLILALFGQSWGYSYLMISHTAS-KSHYAVCFALAKGLAAAGHEVTLVSPFPQRKPIKNIIDVETPNIITV--------------MGVYKARILENAKKPVLLRYPRISLMGLDITESLLKEPKVQELLKQ-NR--TFDGVICETFMNDAHYGFAEHFGAPLITLSSLGATGWTSDLVGTPSPPSYVPHSLL--RFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFP--NNKQ--DFYRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAP-KPLPQNIRKFIEEA-EHGVIYFSLGSNLNSKDLPENKRKAIVETLRGLKYRVIWKYEEETFVD-KPDNVLISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHK--GAKYLRSACQDLNFIQYHNLDVLATFFSVIGLTVIFVFLLVR--------FLVTIVNGFLYKPSSKLKIN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQT0-1", "uniprot_id": "Q9VQT0_DROME", "id": "Q9VQT0-1", "name": "", "aln": "-----MTTCLRSGVLIIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQAGAYPNYEELLISAPGEDQSS-----TTINLVPLTEHTPTRSLGVLIREYVDLHEEGQKTCEHLFASGHIERAIER-HRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDLPDTPAFIQSEFV--GFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLG----VEVDVEEVARTQTAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKA-EQELPQNIANFLNQS-AEGVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKALAELSKN-SYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSLDSVALILLPLILLILVLCYLCKRNPS--------------KLAHKKVGKKPKRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ46-1", "uniprot_id": "Q9VJ46_DROME", "id": "Q9VJ46-1", "name": "UDP-glucuronosyltransferase", "aln": "----MWSPRVALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHP--VAHYKDFPLTG--MDKLT-----NSVDLK----FFEKRTFYSHFQEFFLLYDWGKQTCNLTLRSEALQQILRR-PGR--FDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPSHIPALFM--AQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFG----HDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQK---SKPLPADLQRILDNA-EEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPN-QPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKALDK-KFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTG--GAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLLRLCCG--------------SSAAQKTKKD----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * .* : : . :* :: : : :: : * * : . . : : . . :** * *. :: ::: : * : :* ** : : .. :::*::. . : . .* ** :* :. * :*** . *. : . *:: * : :* * * . : . : . : * ... . . * : *.: .* :: : ** . . : ", "identical_positions": 35, "similar_positions": 77, "identity": "6.13%" }, { "cls_id": "homologset.agr.RGD:620896", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M1X2-1", "uniprot_id": "A0ABK0M1X2_RAT", "id": "A0ABK0M1X2-1", "name": "CD99 antigen-like protein 2", "aln": "MVARLTTLLVCLVFSLATLVQRGPRDQTRVIRLEGYGDFDDFNLEDALKETSSVKQ--SHFSTTTR-RTGTTRAPANP-------------------------AERWDHMTTTTTKRPGTTRAPSNPLELDGFDLEDALDDRNDLD-GPKKPSTGE----------------GGGLSDKDLEDILGGGGYKPDKNKGGGGGYGSQD---DPGSG----AVTDPGTIAGLVSALAAALLGAVSGYLSYQHRKFCFSVQRGLDAAYVKGENLEAVVCEEPRVEAAMCEAPPVTDSTQHSQPTEPLAP-ERPRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIF0-1", "uniprot_id": "C99L2_MOUSE", "id": "Q8BIF0-1", "name": "CD99 antigen-like protein 2", "aln": "MVARLTAFLVCLVFSLATLVQRG------------YGDTDGFNLEDALKETSSVKQRWDHFSTTTR-RPVTTRAPANP-------------------------AERWDHVATTTTRRPGTTRAPSNPMELDGFDLEDALDDRNDLD-GPKKPSAGE----------------AGGWSDKDLEDIVEGGGYKPDKNKGGGG-YGSND---DPGSG----ISTETGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVCEEP----------QVTYSKQETQSAEPPPP-EPPRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCZ2-1", "uniprot_id": "C99L2_HUMAN", "id": "Q8TCZ2-1", "name": "CD99 antigen-like protein 2", "aln": "MVAWRSAFLVCLAFSLATLVQRG------------SGDFDDFNLEDAVKETSSVKQPWDHTTTTTTNRPGTTRAPAKPPGSGLDLADALDDQDDGRRKPGIGGRERWNHVTTTT-KRPVTTRAPANTLGND-FDLADALDDRNDRDDGRRKPIAG-----------------GGGFSDKDLEDIVGGGEYKPDKGKGDGR-YGSND---DPGSG----MVAEPGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVCEEP----------QVKYSTLHTQSAEPPPPPEPARI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBW9-1", "uniprot_id": "C99L2_DANRE", "id": "Q6DBW9-1", "name": "CD99 antigen-like protein 2", "aln": "MEKTLWTWTLLAVFSL--LVVKG--------------MSDGLDLADALGDDDDDEPTTKPPKADPG-AGGAGGAAVKP----------------------------TLKPVKPTVKEPAKPKP--KQTGLDDFDLADALNPDNDIKGKGKDSGKGDKEVGGGSRDDGTPNSRGSQFSDDDLLDVGNDNSYKPDKGKGGKGGSSSNVGDLDPADDNNYDTMAETGTIAGIVSAVAMALVGAVSSYISYQKKKLCFSIQQSLNADMVKADAPDAVVAQEP----------QVQQTLLQPPNAEPPTEENAV--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : .*** ** :* *.::* **: : .. : . .: . : *..:* : ...* :.* ..:. : * *** ***: ** . :.. * .. **.** *: .. *****.**. .*: **... ::.*****:.**:* **:****.*:***::*:***:*:.*:* **.: :***.:** * : .. :** . : ", "identical_positions": 75, "similar_positions": 76, "identity": "24.12%" }, { "cls_id": "homologset.agr.RGD:620897", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64623-1", "uniprot_id": "DUS1_RAT", "id": "Q64623-1", "name": "Dual specificity protein phosphatase 1", "aln": "----------MVMEVGILDAGGLRALLRERAAQCLLLDCRSFFAFNAGHIVGSVNVRFSTIVRRRAKGAMGLEHIVPNTELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARSTQVFFLQGGYEAFSASCPELCSKQSTPMGLSLPLSTSVP-DSAESGCSSCSTPLYDQGGPVEILSFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAP-HCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHPTNSALNYLQSPITTSPSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28563-1", "uniprot_id": "DUS1_MOUSE", "id": "P28563-1", "name": "Dual specificity protein phosphatase 1", "aln": "----------MVMEVGILDAGGLRALLREGAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSASLDGAKRDGTLALAAGALCREARSTQVFFLQGGYEAFSASCPELCSKQSTPTGLSLPLSTSVP-DSAESGCSSCSTPLYDQGGPVEILSFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAP-HCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHPTNSALNYLKSPITTSPSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28562-1", "uniprot_id": "DUS1_HUMAN", "id": "P28562-1", "name": "Dual specificity protein phosphatase 1", "aln": "----------MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVP-DSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAP-HCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PEI8-1", "uniprot_id": "A0A8M1PEI8_DANRE", "id": "A0A8M1PEI8-1", "name": "Dual specificity protein phosphatase", "aln": "MYLELSFCTMVIMEVPTIDSASLRDMLEGDDPDCLVLDCRSFFSFSVSHISGSSNVRFSTIVRRRARGGLGLEHIVPNEDTRNRLLSGEYQSVVFLDDHSLEMGEVKKDGTLMLAVNALCRKQCGASVYLLKGGFDTFSAEFPEKCTKTVPPQGLSLPLSSNCHSNTADSSCNTCTTPLYDQGGPVEILPFLYLGSAYHASRKDMLDMLGITALINVSSNCPNHFEDHYQYKSIPVEDNHKANISSWFNEAIEFIDSVRNKGGRVFVHCQAGISRSATICLAYLMRTNRVKLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLASSTCSSEAGSPAIG------KNSTVFNF----PVHTAASPLSFLQSPITTSPSC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*** :*:..** :* .:**:*******:*...** ** ************:*.:******** : *.***:* *::**:**::* :. .*:**** **..****: .:.*::*:**:::***. ** *:* .* *******:. ::*:*.*.:*:*************.***************** **********:*******.***************:*********:****::: *******************************:********************************. **:******:. ..:***** ***.: *.*.:*:*********", "identical_positions": 253, "similar_positions": 75, "identity": "66.75%" }, { "cls_id": "homologset.agr.RGD:620898", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14A28-1", "uniprot_id": "PROK1_MOUSE", "id": "Q14A28-1", "name": "Prokineticin-1", "aln": "MRGAVHIFIMLLLATASDCAVITGACERDIQCGAGTCCAISLWLRGLRLCTPLGREGEECHPGSHKIPFLRKRQHHTCPCSPSLLCSRFPDGRYRCFRDLKNANF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R414-1", "uniprot_id": "PROK1_RAT", "id": "Q8R414-1", "name": "Prokineticin-1", "aln": "MRGAVQVFIMLLLATVSDCAVITGACERDVQCGAGTCCAISLWLRGLRLCTPLGREGEECHPGSHKIPFFRKRQHHTCPCSPSLLCSRFPDGRYRCSQDLKNVNF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58294-1", "uniprot_id": "PROK1_HUMAN", "id": "P58294-1", "name": "Prokineticin-1", "aln": "MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLGREGEECHPGSHKVPFFRKRKHHTCPCLPNLLCSRFPDGRYRCSMDLKNINF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.:: *****.*.*************:******************:*****************:**:***:****** *.************* **** **", "identical_positions": 89, "similar_positions": 11, "identity": "84.76%" }, { "cls_id": "homologset.agr.RGD:620899", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PF93-1", "uniprot_id": "PK3C3_MOUSE", "id": "Q6PF93-1", "name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "aln": "-MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAE--GKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGSAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTRTPGRT---------SSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKE-YGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNATTRDQLNIIVS-YPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYEN--------------FDDIKNGLEPTKK-DSQTSAS-ESLSNSGVSSGDIDSSQIITNPLPPVASPPPASKAKEVSDGE----------------------------------------NLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQD-TQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNE--KMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGG-KYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSETGPYGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88763-1", "uniprot_id": "PK3C3_RAT", "id": "O88763-1", "name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "aln": "-MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAE--GKPLALPVRTSYKPFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGRAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTRTPGRT---------SSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKE-YGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNATTRDQLNIIVS-YPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYEN--------------FDDIKNGLEPTKK-DSQASVS-ESLSSSGVSSADIDSSQIITNPLPPVASPPPASKSKEVSDGE----------------------------------------NLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQD-TQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNE--KMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGG-KYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSETGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NEB9-1", "uniprot_id": "PK3C3_HUMAN", "id": "Q8NEB9-1", "name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "aln": "-MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAE--GKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRT---------SSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKE-YGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIVS-YPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYEN--------------FDDIKNGLEPTKK-DSQSSVS-ENVSNSGINSAEIDSSQIITSPLPSVSSPPPASKTKEVPDGE----------------------------------------NLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQD-TQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNE--KMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGG-KYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q9F3-1", "uniprot_id": "F1Q9F3_DANRE", "id": "F1Q9F3-1", "name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "aln": "--MDTDKFNYVYSCDLDINVQLKIGSLEGKREQKSYKALLEDPMLRFSGLYQESCSDLYVTCQVFAE--GKPLALPVRTSYKAFSTRWNWNEWLRLPVKYPDLPQSAQVTLTVWDVYGPGRATPVGGTTVTLFGKYGMFRQGMHDLKVWPGVEGDGTEPTSTPGRT---------SSSLAEDQMGRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFPRVKSGERE-YSIVYYEKDADESSPLPTSSDIVKVPDPQMCMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIVS-YPPTKQLSSEEQDLVWKFRYYLTTQEKALTKFLKCVNWDLPQEAKQALELLGKWRPMDVEDSLELLSSQFTNPTVRRYAVARLQQADDEDLLMYLLQLVQALKYEN--------------FNDIQGGLEPANKRDNQGGLT-ESS-----TTGDLDSSQLAS----AIAVMPSSQKGKEGTDGE----------------------------------------NLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQD-TQQRDPKTHDMYLNVMRRFSQALLKGDKSVRVMRSLLASQQTFVDRLVQLMKAVQRESGNRKKKTERLQSLLADNE--KVNLSEIEPIPLPLEPQIRIKGIIPETATLFKSALMPAKLIFKTEDGE-QYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFVQSVPVAEVLATEGNIQSFFRKYAPNDKGPYGISSEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLSKEMVEGMGGMQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVGALFAAVVEQIHKFAQYWRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1M7-1", "uniprot_id": "Q9W1M7_DROME", "id": "Q9W1M7-1", "name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "aln": "MDQPDDHFRYIHSSSLHERVQIKVGTLEGKKRQPDYEKLLEDPILRFSGLYSEEHPSFQVRLQVFNQ--GRPYCLPVTSSYKAFGKRWSWNEWVTLPLQFSDLPRSAMLVLTILDCSGAGQTTVIGGTSISMFGKDGMFRQGMYDLRVWLGVEGDGNFPSRTPGKG---------KES-SKSQMQRLGKLAKKHRNGQVQKVDWLDRLTFREIEVINEREKRMSDYMFLMIEFPAIVVDDMYNYAVVYFEPEGDVKYKLPAKPKLVSVPDSEIQMENLVERKHHRLARSERSGISDRDAKPTASIRDQLHTIVYRYPPTYVLSSEEQDLVWKFRFYLSSHKKALTKFLKCINWKLEDEVTQALWMLANWAPMDVEDALELLSPTFTHPQVRKYAVSRLAQAPDEDLLLYLLQLVQALKYEDPRHIVHLHGCIFPERDVVRSILDDNGSLLDQSSLSDLSATSSGLHGSVIPANQRAASVLAAIKSDKSVSPGSAGGSGSGGQGSVALPNPSAPATPGSSSLPCDSNSNALMLAEGISFGSVPANLCTFLIQRACTNATLANYFYWYLSIEVEEVESVRKQDERAHDMYAMVLKMFLKVLENGNFNLRGIFYNLRKQRRFIDELVKLVKLVAKEPGNRNKKTEKFQKLLAEQDMFKVNFTNFEPIPFPLDPEIYITKIVPMRTSLFKSALMPAKLTFVTSIAHHEYAAIFKHGDDLRQDQLILQMITLMDKLLRRENLDLKLTPYKVLATSSKHGFLQYVDSCTVAEVLAREGNIHNFFRKHHPCDNGPYGISAEVMDTYIKSCAGYCVITYLLGVGDRHLDNLLLTTNGKLFHIDFGYILGRDPKPMPPPMKLSKEMVEAMGGISSEHHHEFRKQCYTAYLHLRRHANVMLNLFSLMVDATVPDIALEPDKAVKKVEENLQLGLTDEEAVQHLQSLLDVSITAVMPALVEQIHRFTQYWRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22543-1", "uniprot_id": "VPS34_YEAST", "id": "P22543-1", "name": "Phosphatidylinositol 3-kinase VPS34", "aln": "--MSLNNITFCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELMLIGSNVFPSSDLIVSLQVFDKERNRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLTFSSHLRIILWEYNGSKQIPFFNLETSIFNLKDCTLKRGFESLKFRYDVIDHCEVVTDNKDQENLNKYFQGEFTRLPWLDEITISKLRKQRENRTWPQGTFVLNLEFPMLELPVVFIEREIMNTQMNIPTLKNNPGLSTDLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKYRRLERASKNANLDKQVKPDIKKRDYLNKIIN-YPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFEN-----------------LSTFSDKSNS--EFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVIS-------------------------------------------PLAEFLIRRALVNPRLGSFFYWYLKSESEDKP-----------YLDQILSSFWSRLDKKS------RNILNDQVRLINVLRECCETIKRLKDTTAKKMELLVHLLETKVR---PLVKVRPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFKTTLNQ-PYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVNALLPIVIDHLHNLAQYWRT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : * .*. :::*: :***:: . . : :* * : * ..: * *** : .: **: :.* .* . .*: *: **:: :*. .: : : : : *. .. : : * :::*: .*:. .* . : . .: . : :.** * :.: : :: .* * :*: :* : : . : . :.. *.: :: :* *:::* *: :.. *:: ** ** *: *: *** *: .*:. :**:*:** .::*****:*:. * .* :.* :: .* :*::*:****.. :.: ** *** ** :* *::* :******:*: :*: : : . . . : :.: .: . . *. *** ** *. *..::***: * *: :: * . * : . * * ::: * . : : : .. ** * : ** : : ... *.:**:*:: * : * :.:***:* * :: * * * :** *********::*:*:**::**:.**:********:***..:.* :::: . .:*.:* .* .::: : * :... *:.. *:*.::***********:************:* *::** *******:****:** *** :::*.:** .*.::.:**. *:.*: *** :.::****.** :.:*** ::*: :: :*.:.:.*.:::*:*. ::*.*:: *: *::. :::::*.::**** ", "identical_positions": 242, "similar_positions": 291, "identity": "25.18%" }, { "cls_id": "homologset.agr.RGD:620900", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15291-1", "uniprot_id": "B4GT1_HUMAN", "id": "P15291-1", "name": "Beta-1,4-galactosyltransferase 1", "aln": "MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPLQGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVPHTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAIIIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYDYTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLTINGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIAHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P80225-1", "uniprot_id": "B4GT1_RAT", "id": "P80225-1", "name": "Beta-1,4-galactosyltransferase 1", "aln": "--------------PGATLQXAXXLLVAVXAX---------------------------------------------------PPPPLGVX--PKPX----------PG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:** * ***** * ******. *:* ** ", "identical_positions": 22, "similar_positions": 3, "identity": "5.53%" }, { "cls_id": "homologset.agr.RGD:620901", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUW5-1", "uniprot_id": "A0A8I5ZUW5_RAT", "id": "A0A8I5ZUW5-1", "name": "", "aln": "MATGGGPFEEVMHDQDLPNW--SNDSVDDRLNNMEWGGQQKKANRSSEKNKKKFGVASDKRVTNDISPESSPGVGRRRTKVPHTFPHSRYMTQMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLG-ENRKPFNFLPMQINTNKSKDATASLP----KRETTTSAQCKELFASALSN-----DLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIEHLKEQEKSYMKFLQKILARENEEED---VRTIDSAVGSGSVAESTSLNVDVQSEASDTTEASFSLRIRPCIEDKLGNSASQEQVSDIDVTTSPKGKGDKAPQNDRELRPNRKCSRKRGFPSKARDPQQEPMEETENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVTETTGSLSGVSITSELNEELNDLIQRFHNQLRDSQP-------PAVPDNRRQAESLSLTREISQSRNPSVS-EHLPDEK---------VQLFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSFVPSTSLPRSGDKRSSTVALSAPVGFAPAVNGESNSLISSVPCPAASLVSQNESENEGHLNPAEKLQKLNEVQKRLNELRELVHYYEQTSDMMTDAVNENTK--DEETE-----ESEYDSEHEHSEPVTNIRN---PQVASTWNEVNTNSNTQRGSNNREGRSINSSCEINNRSAANIRPLTTPL-LDCRYNREGEQRLRVARGED---EEEEVEEEGVSGASLSS--RRSSLVDEAPEDEEFEQKISRLMAAKEKLKQLQDLVAMVQDDDATQ-VLVPAASNLDDFYVAEEDTKQNSNNARENSNK--VDTGVNEKTREKFYEAKLQQQQRELKQLQEERKKLIEIQEKIQAVQKACPDLQLSATSISSGPTKKYLPAITSTPTVNENETSTS--------KCDIEPEDSSVVDNELWSDMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLGTPQQSRTEKTMATWGGSTQCALDEDGDEDGYLSEGIVRTDEEEEEEQDASSNDNFPMYHP-SMNQNSYNVKETKNRWKNHRPVSADGN-YRPLAKTRQQNIS-------MQRQENLRWVSELSYIE--EKEQWQEQINQLKKQLDFSVNICQTLMQDQQTLSCLLQTLLTGPYSVLPSNVASPQVHLIMHQLNQCYTQLTWQQNNVQRLKQMLTELMRQQNQHPEKPRSKERGSSASHPSSPSLFCPFSFPTQPVNLLNLPGFTNFPSFAPGMNFSPLFPSNFGDFSQNVSTPTEQQQPLAQNPSGKTEYMAFPKPFESSSSLGAEKQRNQKQPEEETENTKTPWLYD-QEGGVEKPFFKTGFAVSVEKATNSNRKRQPDTSRRGRQFDEESLESFSSMPDPIDPTTVTKTFKT-RKASAQASLASKDKTPKSKSKKRNSTQLKSRVKTIGYESASVSSTCEPCKSRNRHSAQTEEPVQAKLFSRKNHEQLEKIIKYSRSAEISS-------------------ETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESDEKEGENIKSVNSGTWVASN-SELTPSESLVTTDDETFEKNFERET----HKITEQNDADNVSVMSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTETESNSNMRCTCRVIEDEDGAAATTTVSNAEETPIIENHSSPQPTSDVSAVPCPRIDTQQLDRQIKAIMKEVIPFLKEHMDEVCSSQLLTSVRRMVLTLTQQNDESKEFVKFFHKQLGSILQDSLAKFAGRKLKDCGEDLLVEISEVLFNELAFFKLMQDLDNNSIAVKQRCKRKIEAAGVIQSYAKEAKRILEGDRGSPAGEIDDEDKDKDETETVKQTQTSEVYDAKGPKNVRSDVSDQEEDEESERCPVSINLSKAESQALTNYGSGEDENEDEEMEDFEESPVDVQTSLQANTETTEENEHDNQVLQHDLEKTQESTNVPSDQEGTSKNDQDSSPVKPCYLNILENEQHLNSATHKDSLTTTTDSSKQPDPMPLPLTASETLVPRVKEVKSAQETPESSLAGSPDTESPVLVNDYEAESGNISQKSDEEDFVKVEDLPLKLTVCSEAELRKKMVEEEQKNHLAGEICEMQTEELA---GNPQILKEPETVGAQSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R0L6-1", "uniprot_id": "PCM1_MOUSE", "id": "Q9R0L6-1", "name": "Pericentriolar material 1 protein", "aln": "MATGGGPFEEVMHDQDLPNW--SNDSVDDRLNNMEWGGQQKKANRSSEKNKKKFGVASDKRVTNAISPESSPGVGRRRTKIPHTFPHSRYMTQMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLS-ENRKPFNFLPMQINTNKSKDATASLP----KREMTTSAQCKELFASALSN-----DLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIEHLKEQEKSYMKFLQKILAR---------------------------------------------------------------------------------------------------------DPQQEPMEETENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVTETTGSLSGVSITSELNEELNDLIQRFHNQLRDSQP-------PAVPDNRRQAESLSLTREISQSRNPSVS-EHLPDEK---------VQLFSKMRVLQEKKQKMDKLLGELHNLRDQHLNNSSFVPSTSLQRSGDKRSSTVALSAPVGFASAVNGEANSLISSVPCPATSLVSQNESENEGHLNPAEKLQKLNEVQKRLNELRELVHYYEQTSDMMTDAVNENTK--DEETE-----ESEYDSEHENSEPVTNIRN---PQVASTWNEVNTNSNTQCGSNNRDGRPVNSNCEINNRSAANIRALNMPP-LDCRYNREGEQRLHVAHGED---EEEEVEEEGVSGASLSS--RRSSLVDEAPEDEEFEQKISRLMAAKEKLKQLQDLVAMVQDDDATQ-VVVPAASNLDDFYAAEEDIKQNSNNARENSNK--IDTGVNEKTREKFYEAKLQQQQRELKQLQEERKKLIEIQEKIQAVQKACPDLQLSATSISSGPTKKYLPAITSTPTVNENDSSTS--------KCVIDPEDSSVVDNELWSDMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETSSPVAISLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDEEGDEDGYLSEGIVRTDEEEEEEQDASSNDNFPIYPP-SMNQNSYNVKETKTRWKSNRPVSADGN-YRPLAKTRQQNIS-------MQRQENLRWVSELSYIE--EKEQWQEQINQLKKQLDFSVNICQTLMQDQQTLSCLLQTLLTGPYSVLPSNVASPQVHLIMHQLNQCYTQLTWQQNNVQRLKQMLTELMRQQNQHPEKPRSKERGSSASHPSSPNLFCPFSFPTQPVNLFNLPGFTNFPSFAPGMNFSPLFPSNFGDFSQNVSTPTEQQQPLAQNPSGKTEYMAFPKPFESSSSLGAEKQRNQKQPEEEAENTKTPWLYD-QEGGVEKPFFKTGFTESVEKATNSNRKNQPDTSRRRRQFDEESLESFSSMPDPIDPTTVTKTFKT-RKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIGYESASVSSTCEPCKNRNRHSAQTEEPVQAKLFSRKNHEQLEKIIKYSRSAEISS-------------------ETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESDEREGENVKPVNSGTWVASN-SELTPSESLVTTDDETFEKNFERET----HKVSEQNDADNVSVMSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTETESHSNMRCTCRVIEDEDGAAAAATVSNSEETPIIENHNSPQPISDVSAVPCPRIDTQQLDRQIKAIMKEVIPFLKEHMDEVCSSQLLTSVRRMVLTLTQQNDESKEFVKFFHKQLGSILQDSLAKFAGRKLKDCGEDLLVEISEVLFNELAFFKLMQDLDNNSIAVKQRCKRKIEAAGVRQSYAKEAKRILEGDHGSPAGEIDDEDKDKDETETVKQTQTSEVYDAKGPKNVRSDVSDQEEDEESERCPVSINLSKAESQALTNYGSGEDENEDEEMEDFEESPVDIQTSLQANTETTEENEHDSQILQHDLEKTPESTNVPSDQEPTSKNDQDSSPVKPCYLNILENEQQLNSATHKDSLTTT-DSSKQPEPLPLPLAASETLVPRVKEVKSAQETPESSLAGSPDTESPVLVNDYEAESGNISQKSDEEDFVKVEDLPLKLTVYSEEELRKKMIEEEQKNHLSGEICEMQTEELA---GNSQILKEPETVGAQSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15154-1", "uniprot_id": "PCM1_HUMAN", "id": "Q15154-1", "name": "Pericentriolar material 1 protein", "aln": "MATGGGPFEDGMNDQDLPNW--SNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMSQMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLS-ENRKPFNFLPMQINTNKSKDASTNPP----NRETIGSAQCKELFASALSN-----DLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILAR---------------------------------------------------------------------------------------------------------DPQQEPMEEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQP-------PAVPDNRRQAESLSLTREVSQSRKPSAS-ERLPDEK---------VELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNS----SSSPQRSVDQRS-TSAPSASVGLAPVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRK--DEETE-----ESEYDSEHENSEPVTNIRN---PQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLDCRYNREGEQEIHVAQGEDDEEEEEEAEEEGVSGASLSS--HRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANKTQKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTS--------KSVFEPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDEEGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADEN-YRPLAKTRQQNIS-------MQRQENLRWVSELSYVE--EKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQMLNELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQNSSGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYE-QEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLESFSSMPDPVDPTTVTKTFKT-RKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRKNHEQLEKIIKCNRSTEISS-------------------ETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEK-GENVKSVNSGTWIASN-SELTPSESLATTDDETFEKNFERET----HKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTEAESNSNMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEHMDEVCSSQLLTSVRRMVLTLTQQNDESKEFVKFFHKQLGSILQDSLAKFAGRKLKDCGEDLLVEISEVLFNELAFFKLMQDLDNNSITVKQRCKRKIEATGVIQSCAKEAKRILE-DHGSPAGEIDDEDKDKDETETVKQTQTSEVYD--GPKNVRSDISDQEEDEESEGCPVSINLSKAETQALTNYGSGEDENEDEEMEEFEEGPVDVQTSLQANTEATEENEHDEQVLQRDFKKTAESKNVPLEREATSKNDQNNCPVKPCYLNILEDEQPLNSAAHKESPPTV-DSTQQPNPLPLRLPEMEPLVPRVKEVKSAQETPESSLAGSPDTESPVLVNDYEAESGNISQKSDEEDFVKVEDLPLKLTIYSEADLRKKMVEEEQKNHLSGEICEMQTEELA---GNSETLKEPETVGAQSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GAP5-1", "uniprot_id": "A0AC58GAP5_DANRE", "id": "A0AC58GAP5-1", "name": "", "aln": "MATGGTPFEDGTDEQEMQNWTISNGSLDDRLNNMDWGVQQKKANRSSEKNRKKFSAMSESRLTNDISPESTPGAGRRRARTPHSFPHVKYSTQMSVPDQAELDRLRQVINFTDLDERSIGSDSQGRVTAANNQRQLSTEAKKPFNFLPIHLNTNKSKEPTASTSSTPGGKEHKKQSPGKELFAPVPAVVKEPFSLDGAQRLGLEDGRGELSIDSSQIVSKLVQIREYIGKATSMRDDLVEKNDVPANVERLSLLITHLKEQEKSYLRFLQKMLARENEDDDDDEGATVDSAVGSGSVAESTSLNLEPRSETSSATG---------------------------------------------------------------HGVCREQKEELENMRKQHDLLKKMLEQQEQLRALQGRQAALLAMQQSAELAIAVMDDTVVTETTGSVSGRSITSELNDELNDLIQRFHNQLHDSQAYQTVNQSQVVPDNRRQAECLSLSREVCRSRTTHNSRGQLPSSAPLTTASTSASAKLSKLQELQDKKQTMDKILQELHSLRDQTLNNSS-------CQSVSQRSARVGMSE----RPSVLGREGNGPRPVRQGSSTYTQIDDNS-----HSADKLRKLKEVHKRLNELRELVQYYEQTSDMVVDTVNENVKEEDEETEDGSLFEAMFDSEQENHEPVTNIRNPAQPQTPSNWMDMNSLTKTRSASNNRDGR-LNTECEINNRSAANLRSLNIPSVIECQHNRDRPYVGVKDEDDEEVLEDDDGARGGGGGGGRDSDGSGSSHRSSLGGDAEYAQKVHRLQTAKQKLRQLQELVAMVQSDDTDG----TTAN-------EDEGLKQQPNNTRATAPKAQRDIALCDKARERLYEEKLKQQQHELKQLHEERQRLLEIQGKIQDIQWACPDLQSSVSSSASGQMSRKIPAAASTPAPVPLQSSSSAKANTSGLKPTTEPPPVTVTDNELWTEMRRHQMLREELRQRRKQLESLMAEQQRRSTLPDSP------FRSDTHE---TQSYSRDERTVATWGGSTQCPLGDEDDD--YSSEVGAEEDDDDDERDEGEESSSTDERHACSTQKQRNYNRNNREGLKVLREVNTSPSPRRSRGRSRQQPQSERGSSSKAKRQENLRWAADLSLAEGAAPAHWQEQITHLQKQLNFSTTMCQTLLQDQQTLSYMLQALLTGPCGVVPNNVTSPQVPLIMHQLNQCYTQLAWQQNNVNRLKQTLNDLLRQQ-QSQSSSGQQQHQSVAHDPASPSMFLNYPS----VNALNIPGLPNFSPFPTGFNFAPMFPPSVGDFQQNQASSDQHHDP---NISLKTEYMSFPPPLQRSPLNNAEK-RFQSHSDNLTDANNSSWLNSSLNRSSQRPILTSDHPSQVEQNSLSSSPVPHPSTSRDRSYIPDSQESMSSLPDRADPTTVTKTFRAGRKAAAQASLASRDKTPNMKSRRKRGRGQKN-TASVDSDSVSSDSHFE----RERSNQVKYKELNQGLLDKLTQEKLDSKTKNSKPNDLSSAYAWRTPFLSNRIACTEVPDVSSDFSLFEALRETIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYSLQDIVTRHLTEKSVA-DEQASSLGPAVWATGSQSELTPSESLATSDNDASDKIVTVKSNSVLKRVPDRDSMDNESLLSTSSNLEPFASDDLGNTVIHLDKALARMREYERMKLRAECNTDN-------PEHSSAIAAATVASPQGTQGAGHLS--------TDAHCPQIDTQQLDRQIKAIMTEVIPFLKEHVGEVCSQKLLKAVRHMVLNLTQQNDESKEFVRFFHRQLEGILQDSLSKFVGRKLQDCGEDLLVEISEILFNELAFFRLMQDLDQNTSKNKLRTKRRSDHTSPKHSPHTEEMKTLEREKTFSPSYFD-EDRDQDETERQEMPHEREE-----EKEKEAQSSEASEVEEEEGLPLSISLSKAETKALCNYGSGEDENEVEEMEEFEAGPVEVQTSLQASMDNTSEHRESSALQN----ETPQETKSDQDSSESSQLNSEPSDPKVIVQPPEEGGEEEKSASGDEEEEKE-DSTSAP----------------------VQETPQSSDSASPDTDSPVMINTDEAGSGNTSQRSDEEDFVKVEDLPIQMSVLCEEELCKRISEEQQNNNLTAEILNGNTSELTGLVGNAQTLKEPETIGAQSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ***: .:*:: ** ** .:*******:** ************:***.. *:.*:** *****:**.****:: **:*** :* :*****:****::*:* ***:***:**********.*****:***. * :*******:::******:.::. . :* .: *****.. : .* ::. ****** :::******:*****:** **:***:******: .******: ** *********::**:*:*** . :* ** **::*******:**:*****************:*:.** *******:**:**:**:** *******:*************:***. .*********.***:**:.:**.. * :**.. :**:: **:***.***:* ***.**** **** :* .:** . * . * *. .. .* ::: .. ::.. :.::**:**:**:**********:********:.*:**** * ***** *: :***:*: ******** **..*.* ::*: :::: ****:** :*:.**********:*.*. * ::*::**: ..:: *::: . * .*.. .* ** .. * *: **: ** :**:**:***:******.**: .:*. :*. **:.**:* .: * * .: :*:**::** **:***:*****:***::*::** *** :* ****** *.:* .. .: :** :***: ::*:* * :* ::.*****::****:**************:****:***. *.::. :*** * * . ** *:*:*********.*.::.*: * ** .. *::::*.::...... . * ::: ::.: * ..:. . *. .::*** * :*******.::** * :*****.:*:***:**..:****:******* :**:***** .*:*.**:**** :************:******:**** *.:*:*** * ... ::: * * .*.**.:* :. ** :*:**:.**..*..*:**:*:**...***.** ::. ::::* * * *****:** *:: *. .*** * :. .:: .: ..:.** . : ::*::.:... .**: : *. :. * *.: :* **:**:** *********:: ***:*******:****: **:::.. *. . .: :*.* .* * *:* . . : :: ::.: .:*:*:. * .:. ::** :..****:*****:*****************************************:*****:**::*. .*: ..:....* :.. *********.*:*::: :* . :: :::.:::. ** *::*.***:****:***********:************ .:*.::: : ..* * :** . : * : . : **:**************.*********:.****.:**.:**:***.************:***:** .******:**.****:************:********:******:*: * * **: : :. :* .* : ** :: ... :* **:*:**** : .: * *: .:: *: .* **.* *:**.*****::** ********** ****:** .**::******. : *.*:.... : : :* :..: : . :*: :.: . * *. : :**: .:. . **:. * .****:** :.****:***::* ** *** **:*************::::: .* :* *:: **:*:*:*:.** : :*.**: **.: ******:**** ", "identical_positions": 1003, "similar_positions": 576, "identity": "45.04%" }, { "cls_id": "homologset.agr.RGD:620902", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63030-1", "uniprot_id": "MPC1_MOUSE", "id": "P63030-1", "name": "Mitochondrial pyruvate carrier 1", "aln": "MAGALVRKAADYVR----SKDFRDYLMSTHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHVTNEVAQLIQGGRLINYEM-SKRPSA----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63031-1", "uniprot_id": "MPC1_RAT", "id": "P63031-1", "name": "Mitochondrial pyruvate carrier 1", "aln": "MAGALVRKAADYVR----SKDFRDYLMSTHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHVTNEVAQLIQGGRLINYEM-SKRPSA----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5U8-1", "uniprot_id": "MPC1_HUMAN", "id": "Q9Y5U8-1", "name": "Mitochondrial pyruvate carrier 1", "aln": "MAGALVRKAADYVR----SKDFRDYLMSTHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHATNEVAQLIQGGRLIKHEM-TKTASA----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KSC4-1", "uniprot_id": "MPC1_DROME", "id": "Q7KSC4-1", "name": "Mitochondrial pyruvate carrier 1", "aln": "MS---IRRAMSTTA----SKEWRDYFMSTHFWGPVANWGIPVAALADTQKSPKFISGKMTLALTLYSCIFMRFAYKVQPRNWLLFACHATNATAQSIQGLRFLHYNYGSKEQQA----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53157-1", "uniprot_id": "MPC1_YEAST", "id": "P53157-1", "name": "Mitochondrial pyruvate carrier 1", "aln": "MSQPVQRAAARSFLQKYINKETLKYIFTTHFWGPVSNFGIPIAAIYDLKKDPTLISGPMTFALVTYSGVFMKYALSVSPKNYLLFGCHLINETAQLAQGYRFLKYTYFTTDEEKKALDKEWKEKEKTGKQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * * .*: .*:::*******:*:*:*:**: * :*.* :*** **:** ** **::* .*.*:*:***.** * .** ** *:::: :. . ", "identical_positions": 46, "similar_positions": 31, "identity": "35.38%" }, { "cls_id": "homologset.agr.RGD:620903", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z137-1", "uniprot_id": "B3GA2_RAT", "id": "Q9Z137-1", "name": "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2", "aln": "MKSALCN--RFFILLPWILIVIIMLDVDPRRPAPQLTSRPYFSPHTVGCGGSRVPLRRSSPGRDAAEKRNESRPQLQPEPRLPTIYAITPTYSRPVQKAELTRLANTFRQVAQLHWILVEDRATRSELVSSFLARAGLP--NTHLHVPTPRRYKRPW------LPRATEQRNAGLAWLRQRHQHQSAQPGVLFFADDDNTYSLELFQEMRTTR--KVSVWPVGLVGGRRYERPLVKNG--KVVGWYTGWREDRPFAIDMAGFAVSLQVILSNPKAVFKRRGSQPGMQESDFLKQITTVDELEPKANNCTKVLVWHTRTEKVNLANEP----KYHMDTVNIEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59270-1", "uniprot_id": "B3GA2_MOUSE", "id": "P59270-1", "name": "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2", "aln": "MKSALCS--RFFILLPWILIVIIMLDVDPRRPAPQLTSRPYFSPHAVGCGGSRVPLRRSSPGRDAAEKRNESRPQLQPEPRLPTIYAITPTYSRPVQKAELTRLANTFRQVAQLHWILVEDRATRSELVSSFLARAGLP--NTHLHVPTPRRYKRPW------LPRATEQRNAGLAWLRQRHQHQSAQPGVLFFADDDNTYSLELFQEMRTTR--KVSVWPVGLVGGRRYERPLVKNG--KVVGWYTGWREDRPFAIDMAGFAVSLQVILSNPKAVFKRRGSQPGMQESDFLKQITTVEELEPKASNCTKVLVWHTRTEKVNLANEP----KYHLDTVNIEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPZ5-1", "uniprot_id": "B3GA2_HUMAN", "id": "Q9NPZ5-1", "name": "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2", "aln": "MKSALFT--RFFILLPWILIVIIMLDVDTRRPVPPLTPRPYFSPYAVGRGGARLPLRRGGP-AHGTQKRNQSRPQPQPEPQLPTIYAITPTYSRPVQKAELTRLANTFRQVAQLHWILVEDAAARSELVSRFLARAGLP--STHLHVPTPRRYKRPG------LPRATEQRNAGLAWLRQRHQHQRAQPGVLFFADDDNTYSLELFQEMRTTR--KVSVWPVGLVGGRRYERPLVENG--KVVGWYTGWRADRPFAIDMAGFAVSLQVILSNPKAVFKRRGSQPGMQESDFLKQITTVEELEPKANNCTKVLVWHTRTEKVNLANEP----KYHLDTVKIEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O97422-1", "uniprot_id": "B3GI_DROME", "id": "O97422-1", "name": "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase I", "aln": "MSEVRIRPRQVLILIIVFLVVLMMVHRNGKRTCQGPE---YLQAMFVQG------------------------------DTLPTIYAVTPTYPRPAQKAELTRLSHLFMLLPHLHWIIVEDTNATTPLVRNLLDRAGLEKRSTLLNIKTPSEFKLKGKDPNWIKPRGVEQRNLALAWLRN--HVDVDRHSIVFFMDDDNSYSTELFAEMSKIERGRVGVWPVGLVGGLMVERPLLTEDGTKVTGFNAAWRPERPFPIDMAAFAISMDLFIRNPQATFS-YEVQRGYQESEILRHLTTRDQLQPLANRCTDVLVWHTRTEKTKLAAEEALLKKGQRSDGGMEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*... :.:**: :*:*::*:. : :*. *:.. * ******:****.**.********:: * :.:****:*** : : ** :* **** .* *:: ** .:* **..**** .*****: : : : .::** ****:** *** ** . . :*.********* ****: :. **.*: :.** :***.****.**:*::::: **:*.*. * * ***::*:::** ::*:* *..**.**********.:** * * : . :**", "identical_positions": 135, "similar_positions": 86, "identity": "39.47%" }, { "cls_id": "homologset.agr.RGD:620904", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925Q9-1", "uniprot_id": "SH3K1_RAT", "id": "Q925Q9-1", "name": "SH3 domain-containing kinase-binding protein 1", "aln": "---MVEAIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGR--RGLFPDNFVREIKKDVKKDLLSNKAPEKPMHDVSSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDELGISQDEQLSKSRPEGFLPASLLPFPAHGAKGKTTFEGTILYRAAPGKTEGHRRYYSLRETTGSESDGGDSSSTKSEGANGTVATAAIQPKKVKGVGFGDIFKDKPIKLRPRSIEVENDFLPVEKTIGKKLPPATSTPDPSKTEMDSRTKTKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPSDFDKEGN-----RPKKPP-------------------------------------------------PPSAPVIKQG--------------------------------------AGTTERKHEIKKIPPERPETLPNRTEEKERPEREP--------------------------------KLDLQKP--------------------------------------SVPAIPPKKPRPPKTNSLNRPGVLPPRRPERPVGPLTHTRGDSSKIDLAGSTLSGILDKDLSD--------------------------RSNDIDLEGFDS-VISSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPD-----------------------------------------IFDSPSPEED------------------KEEHISLAHRGIDVSKKTSRTVTISQVSD-NKASLPPKPGTMAAASSGPASLSSVASSPMSSSLGTAG----------------------QRASSPSLFSAEGKAKTESAVSSQAAIEELKMQVRELRTIIETMKDQQKREIKQLLSELDEEKKIRLRLQMEVNDIKKALQSK---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R550-1", "uniprot_id": "SH3K1_MOUSE", "id": "Q8R550-1", "name": "SH3 domain-containing kinase-binding protein 1", "aln": "---MVEAIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGR--RGLFPDNFVREIKKDMKKDLLSNKAPEKPMHDVSSGNALLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDELGISQDEQLSKSRPEGFLPASLLPFPAHGAKGKTTFEGTILYRAAPGKTEGHRRYYSLRETTGSESDGGDSSSTKSEGANGTMATAAIQPKKVKGVGFGDIFKDKPIKLRPRSIEVENDFLPVEKTIGKKLPPATSTPDPSKTEMDSRTKTKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPSDFDKEGN-----RPKKPP-------------------------------------------------PPSAPVVKQG--------------------------------------AGTTERKHEIKKIPPERPETLPNRTEEKERPEREP--------------------------------KLDLQKP--------------------------------------SVPAIPPKKPRPPKTNSLNRPGALPPRRPERPVGPLTHTRGDSPKIDLAGSALSGILDKDLSD--------------------------RSNDIDLEGFDS-VISSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPD-----------------------------------------IFDSPSPEED------------------KEEHISLAHRGIDVSKKTSKTVTISQVSD-NKTSLPPKPGTMAAASSGPASLSSVASSPMSSSLGTAG----------------------QRASSPSLFSTEGKPKMEPAVSSQAAIEELKMQVRELRTIIETMKDQQKREIKQLLSELDEEKKIRLRLQMEVNDIKKALQSK---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96B97-1", "uniprot_id": "SH3K1_HUMAN", "id": "Q96B97-1", "name": "SH3 domain-containing kinase-binding protein 1", "aln": "---MVEAIVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGR--RGLFPDNFVREIKKEMKKDPLTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDELGISQDEQLSKS--------------------------------------------SLRETTGSESDGGDSSSTKSEGANGTVATAAIQPKKVKGVGFGDIFKDKPIKLRPRSIEVENDFLPVEKTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEKEGN-----RPKKPP-------------------------------------------------PPSAPVIKQG--------------------------------------AGTTERKHEIKKIPPERPEMLPNRTEEKERPEREP--------------------------------KLDLQKP--------------------------------------SVPAIPPKKPRPPKTNSLSRPGALPPRRPERPVGPLTHTRGDSPKIDLAGSSLSGILDKDLSD--------------------------RSNDIDLEGFDS-VVSSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPD-----------------------------------------IFDSPSPEED------------------KEEHISLAHRGVDASKKTSKTVTISQVSD-NKASLPPKPGTMAAGGGGPAPLSSAAPSPLSSSLGTAG----------------------HRANSPSLFGTEGKPKMEPAASSQAAVEELRTQVRELRSIIETMKDQQKREIKQLLSELDEEKKIRLRLQMEVNDIKKALQSK---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KI34-1", "uniprot_id": "A0A0B4KI34_DROME", "id": "A0A0B4KI34-1", "name": "", "aln": "MENNICAIVEYEYAAKEPDELDLQKGAIIHRIKQMPGGWWQGTLKASGVTGMFPDNFVRVLESGVSSN----------GNGTTGSGDHIEVGTAVQLRDKSATSNRRCKVIYSYTQVNDDELTLAVGDVIEFLGEVEEGWWRGRLRSKVGVFPSNFVQHIE-PSPVLASKRPP-------------------------------------------------TIGATVTTSALTSKAANVANVAATATVPTGGAVPP--ASTSISTSTTKQATKSRATAAAAASAPAEPAAIVSGSGAAAGGGAAAAVPMLPPKPQ-REFCRVEFPYAPQNDDELELKVDDIIAVISTELPDKGWWKGEIRGKVGVFPDNFVKMLAPSEATAAPPLPRPRPRTRPGMGGTGAGSGSGIIDGVRTPRRTQRGGSFEFLGARMASFITTIFAPINEPPSATQITQNQRKVSNTASTTSHMTTTNSSNSSTTSVTTQQQKEQIGGSSSTTSKVYIKKTGSSSNSTTSSTTTASSSAGRKESFGSRDSLNDILSETGLPTGNVAAQRKSLENKNLDLTKPPGVGASVSIGQQRSSTSSATTSSATTVATGLTSSSVSKSMENMLDEKVKSPPPPVLSKKPSVPLKKTPTGGVPMTGNLLGGKKKNTEG-KLTTAVSHDLADGLAASKMLSGANQLPESGAAGNVVIRRAATIAVEDTDFDRVERASILTDMRQGRVKAPKRRPPSAAINVLGESNNNSVYVNGSGMSGSGGAGSASELSEDGGAGGKTSDDNSTGEEPQLAKPKPREWEKKKAPWMEELKASQVTRKKTSPSVEPRGASVAERTSKLFAAEQAVSSNSSSITTKVQSSAVTSSMFVENSTTSSSVITSSSHTTTNDAIMSRSLSAAKVQTASSDEETRATRPNSLAIRNQRSVSPLVKSSNASSSQ-SQEEKPTSQLNNHQDASSSRVAQLEQRVDKLEGLVLNQQRTIEELVNALKSEAERVKILRSELDKYAQCVTQV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ****::* *:. *** :. * :* .*:: ****:* ::. *:******* ::. :..: : ..... :. * :: ..:. .***:* :** ***** * ***:**.:********.* *..*.*:*****::.:. * *. .: :: *. :.: ..::.. . .*..*:.*.. * ...:. ..:. * *. : . . :. . ..: . . .: . : .:.: :::*:* *** .****** :* .**:::*..: * ***:**:.*: *********:*... . . **:. * ****. :.*. :.:* * *** .. . .. * .. . *: :*** ** *: : :* :.* . *.: :* ::. *:* . .. * : * *: :.:**:* *: * :*. * :. :. *:. .* **. ***** ::. . *. : : .*.*.* *: *: ** ..:::**: .: .*. . *.:*:..* : *. .. . *:.:.* ::** *: **. *. :. ..: . .. ..*. * .. * .: : ::. :* .. .: ** ..:*: : : *. * :::: :**:*: ", "identical_positions": 182, "similar_positions": 260, "identity": "18.09%" }, { "cls_id": "homologset.agr.RGD:620905", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PAM0-1", "uniprot_id": "AAKB2_MOUSE", "id": "Q6PAM0-1", "name": "5'-AMP-activated protein kinase subunit beta-2", "aln": "MGNTTS-ERVSGERHG------------------------------------AKAARAEG-GGHGPG-------KEHKIMVG-----STDDP-------------SVFSLPDSKLPGDKEFVPWQQDLDDSVKP------------------------AQQAR----------------PTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHND---FVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSD----------------------------------FEVFDALKLDSMESSETSCRDLSSSPPGPYGQEMYVFRSEERFKS--------------------PPILPPHLLQVILNKDTNIS-----CDPALLPEPNHVMLNHLYALSIKDSVMVLSATHRYKKKYVTTLLYKPI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QZH4-1", "uniprot_id": "AAKB2_RAT", "id": "Q9QZH4-1", "name": "5'-AMP-activated protein kinase subunit beta-2", "aln": "MGNTTS-ERVSGERHG------------------------------------AKAARAEG-GGHGPG-------KEHKIMVG-----STDDP-------------SVFSLPDSKLPGDKEFVPWQQDLDDSVKP------------------------TQQAR----------------PTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHND---FVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSD----------------------------------FEVFDALKLDSMESSETSCRDLSSSPPGPYGQEMYVFRSEERFKS--------------------PPILPPHLLQVILNKDTNIS-----CDPALLPEPNHVMLNHLYALSTKDSVMVLSATHRYKKKYVTTLLYKPI---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O43741-1", "uniprot_id": "AAKB2_HUMAN", "id": "O43741-1", "name": "5'-AMP-activated protein kinase subunit beta-2", "aln": "MGNTTS-DRVSGERHG------------------------------------AKAARSEGAGGHAPG-------KEHKIMVG-----STDDP-------------SVFSLPDSKLPGDKEFVSWQQDLEDSVKP------------------------TQQAR----------------PTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHND---FVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSD----------------------------------FEVFDALKLDSMESSETSCRDLSSSPPGPYGQEMYAFRSEERFKS--------------------PPILPPHLLQVILNKDTNIS-----CDPALLPEPNHVMLNHLYALSIKDSVMVLSATHRYKKKYVTTLLYKPI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7Q8-1", "uniprot_id": "A1Z7Q8_DROME", "id": "A1Z7Q8-1", "name": "5'-AMP-activated protein kinase subunit beta-1", "aln": "MGNASSSVHMQRERHKSTDLSTPSSPAHFRDSIGGGGAGQGGSAGAAALGAAAGAVGAAGGGGGGGGGQAFSFDKKHTAVLNEGSSQEDDDPYYTGTGTGSTRRGTAHDDATSAVTRDHSSMDNNEEEEEAAVG------------------------AEPATGSQLTGDEDDIRKTALPTVLRWDGGGKNVTISGTFSDWKP-MAMVRSHQN---FVTIIDLPEGDHQYKFCVDGEWKHDPKLKSVENAEGQRNNLVSVRESD----------------------------------FEVFQALAKDSE--------NVTNYAEKEYSQEVPQVKPWEKVSG--------------------PPVLPPHLLQVILNKDTPLS-----CEPTLLPEPNHVMLNHLYALSIKDGVMVLSATHRYRKKYVTTLLYKPI---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04739-1", "uniprot_id": "GAL83_YEAST", "id": "Q04739-1", "name": "SNF1 protein kinase subunit beta-3", "aln": "--MAGDNPENKDAS--------MLDVSDAASNTTINGKHSADSTNEASLAYTFSQMNVDNPNELEPQHP---LRHKSSLIFND----DDDDEIPPYSNHAENGSGETFDSDDDIDASSSSSIDSNEGDIHDADMTGNTLQKMDYQPSQQPDSLQNQGFQQQQEQQQGTVEGKKGRAMMFPVDITWQQGGNKVYVTGSFTGWRKMIGLVPVPGQPGLMHVKLQLPPGTHRFRFIVDNELRFSDYLPTATDQMGNFVNYMEVSAPPDWGNEPQQHLAEKKANHVDDSKLSKRPMSARSRIALEIEKEPDDMGDGYTRFHDETPAKPNLEYTQDIPAVFTDPNVMEQYYLTLDQQQNNHQNMAWLTPPQLPPHLENVILNSYSNAQ---TDNTSGALPIPNHVILNHLATSSIKHNTLCVASIVRYKQKYVTQILYTPLQ--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P34164-1", "uniprot_id": "SIP2_YEAST", "id": "P34164-1", "name": "SNF1 protein kinase subunit beta-2", "aln": "MGTTTSHPAQKKQTTKKCRAPIMSDVREKPSNAQGCEPQEMDAVSKKVTELSLNKCS-DSQDAGQPSREGSITKKKSTLLLRD----EDEPTMPKLS---------VMETAVDTDSGSSSTSDDEEGDIIAQTTEPKQDASPDDDRSGHS-SPREEGQQQIRAKEASGGPSEIKSSLMVPVEIRWQQGGSKVYVTGSFTKWRKMIGLIPDSDNNGSFHVKLRLLPGTHRFRFIVDNELRVSDFLPTATDQMGNFVNYIEVRQPE--KNPTNEKIRSKEADSMR------PPTSDRSSIALQIGKDPDDFGDGYTRFHEDLSPRPPLEYTTDIPAVFTDPSVMERYYYTLDRQQSN-TDTSWLTPPQLPPQLENVILNKYYATQDQFNENNSGALPIPNHVVLNHLVTSSIKHNTLCVASIVRYKQKYVTQILYTPIESS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . :: . :. . : . . . . . . :: : *. : *. **.:* ::*:*. * : :: : : . : * * *:::* **.: . . . * * : * . : * : . . * :: . . . ** ***:* :****. . . ** ****:**** : * *...: ::: **::**** :**.*: ", "identical_positions": 50, "similar_positions": 75, "identity": "11.39%" }, { "cls_id": "homologset.agr.RGD:620906", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V970-1", "uniprot_id": "G3V970_RAT", "id": "G3V970-1", "name": "", "aln": "----------------------------------------------------------------------------------------------MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENTE---NNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNS---------VLLLQSNMGHARS--SNYSLPGLTASQPSHG-------------------LQAHQHQLQDSLLGPL-TSSLVDLGS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62231-1", "uniprot_id": "SIX1_MOUSE", "id": "Q62231-1", "name": "Homeobox protein SIX1", "aln": "----------------------------------------------------------------------------------------------MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENTE---NNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNS---------VLLLQSNMGHARS--SNYSLPGLTASQPSHG-------------------LQAHQHQLQDSLLGPL-TSSLVDLGS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15475-1", "uniprot_id": "SIX1_HUMAN", "id": "Q15475-1", "name": "Homeobox protein SIX1", "aln": "----------------------------------------------------------------------------------------------MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENTE---NNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNS---------VLLLQGNMGHARS--SNYSLPGLTASQPSHG-------------------LQTHQHQLQDSLLGPL-TSSLVDLGS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZ04-1", "uniprot_id": "SIX1B_DANRE", "id": "Q6NZ04-1", "name": "Homeobox protein six1b", "aln": "----------------------------------------------------------------------------------------------MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYTHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENSE---NNNTGANKQNQLSPLDGGKSLMSSSEDEFSPPQSPDQNS---------VLLLQGNMSHPGA--SAYSMTGLGAAQSVHG-------------------MQGHPHQLQDSLLGPL-TSSLVDLGS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6DHF9-1", "uniprot_id": "SIX1A_DANRE", "id": "Q6DHF9-1", "name": "Homeobox protein six1a", "aln": "----------------------------------------------------------------------------------------------MSILPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESYQFSTHNHPKMQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRSVLREWYTHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENGE---NNGVGG-KQSQRSPLDGVKSLMSSSEDEFSPPQSPEHSS---------VLLLQGTMNNPAA--PAYPMPGLGAPHPLHG-------------------MQGHPHQIQDSLLGSL-TSSLVDLGS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27350-1", "uniprot_id": "SO_DROME", "id": "Q27350-1", "name": "Protein sine oculis", "aln": "MLQHPATDFYDLAAANAAAVLTARHTPPYSPTGLSGSVALHNNNNNNSSTSNNNNSTLDIMAHNGGGAGGGLHLNSSSNGGGGGGVVSGGGSGGRENLPSFGFTQEQVACVCEVLQQAGNIERLGRFLWSLPQCDKLQLNESVLKAKAVVAFHRGQYKELYRLLEHHHFSAQNHAKLQALWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRSVLRDWYSHNPYPSPREKRDLAEATGLTTTQVSNWFKNRRQRDRAAEHKDGSTDKQHLDSSSDSEMEGSMLPSQSAQHQQQQQQQQHSPGNSSGNNNGLHQQQLQHVAAEQGLQHHPHQPHPASNIANVAATKSSGGGGGGGVSAAAAAQMQMPPLTAAVAYSHLHSVMGAMPMTAMYDMGEYQHL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ********************.**:*********** **:*: ****************:::***::** ::**.:**.*:* *******:*******************************************.***:**:***********:*************************** *: .. : :.. .. :.. * :. : ...:::.** :*. :.. * *. :. . :..: *.:. * :. .*::*.: ::: *:*. ", "identical_positions": 169, "similar_positions": 71, "identity": "40.62%" }, { "cls_id": "homologset.agr.RGD:620907", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q76MZ3-1", "uniprot_id": "2AAA_MOUSE", "id": "Q76MZ3-1", "name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "aln": "------------------------MAAADG--DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYD-EDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVS-SAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKS-----EIIP-MFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAE---DKSWRVRYMVADKFTELQKAVGP-EITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGD--PNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDN------STLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XI34-1", "uniprot_id": "Q5XI34_RAT", "id": "Q5XI34-1", "name": "", "aln": "------------------------MAAADG--DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYD-EDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVS-SAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKS-----EIIP-MFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAE---DKSWRVRYMVADKFTELQKAVGP-EITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGD--PNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDN------STLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30153-1", "uniprot_id": "2AAA_HUMAN", "id": "P30153-1", "name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "aln": "------------------------MAAADG--DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYD-EDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVS-SAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKS-----EIIP-MFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAE---DKSWRVRYMVADKFTELQKAVGP-EITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGD--PNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDN------STLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36179-1", "uniprot_id": "2AAA_DROME", "id": "P36179-1", "name": "Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit", "aln": "------------------------MAASDKSVDDSLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGEERTRSELIPFLTETIYD-EDEVLLALADQLGNFTSLVGGPEFAMYLIPPLESLATVEETVVRDKAVESLRTVAAEHSAQDLEIHVVPTLQRLVSGDWFTSRTSACGLFSVCYPRVT-QPVKAELRANFRKLCQDETPMVRRAAANKLGEFAKVVETEYLKS-----DLIP-NFVQLAQDDQDSVRLLAVEACVSIAQLLPQDDVEHLVLPTLRQCAS---DSSWRVRYMVAEKFVDLQKAVGP-EITRVDLVPAFQYLLKDAEAEVRAAVATKVKDFCANLDKVNQVQIILSSILPYVRDLVSDPNPHVKSALASVIMGLSPMLGAYQTVEQLLPLFLIQLKDECPEVRLNIISNLDCVNDVIGIQQLSQSLLPAIVELAEDSKWRVRLAIIEYMPALAGQLGQEFFDQKLRGLCMGWLNDHVYAIREAATLNMKKLVEQFGAPWAEQAIIPMILVMSRN--KNYLHRMTCLFCLNVLAEVCGTDITTKLLLPTVLLLAADPVANVRFNVAKTLQKISPFLEA------SVIDAQVKPTLDKLNTDTDVDVKHFAAQAIAGIAAA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31383-1", "uniprot_id": "2AAA_YEAST", "id": "P31383-1", "name": "Protein phosphatase PP2A regulatory subunit A", "aln": "MSGARSTTAGAVPSAATTSTTSTTSNSKDSDSNESLYPLALLMDELKHDDIANRVEAMKKLDTIALALGPERTRNELIPFLTEVAQDDEDEVFAVLAEQLGKFVPYIGGPQYATILLPVLEILASAEETLVREKAVDSLNNVAQELSQEQLFSDFVPLIEHLATADWFSSKVSACGLFKSVIVRIKDDSLRKNILALYLQLAQDDTPMVKRAVGKNLPILIDLLTQNLGLSTDEDWDYISNIFQKIINDNQDSVKFLAVDCLISILKFFNAKGDESHTQDLLNSAVKLIGDEAWRVRYMAADRFSDLASQFSSNQAYIDELVQPFLNLCEDNEGDVREAVAKQVSGFAKFLNDPS---IILNKILPAVQNLSMDESETVRSALASKITNIVLLLNKDQVINNFLPILLNMLRDEFPDVRLNIIASLKVVNDVIGIELLSDSLLPAITELAKDVNWRVRMAIIEYIPILAEQLGMQFFDQQLSDLCLSWLWDTVYSIREAAVNNLKRLTEIFGSDWCRDEIISRLLKFDLQLLENFVSRFTILSALTTLVPVVSLDVVTEQLLPFISHLADDGVPNIRFNVAKSYAVIVKVLIKDEAKYDALIKNTILPSLQTLCQDEDVDVKYFAKKSLAECQELLKN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::****:*:*:***:::*: *::::***.******* ****.**:****:. * ****: .**:***.*.. :***::. *:* ** **:.***:**:***:**. :: * * .:* ..** :::*. .***:*:.******. *:. ..:: :: : :*..*:****:**...:* : .:: : * : *. * :: .*:****::***:. :.* ::: .. * . *..... *.:******.*::* :* . ... : :** .* * :* *.:** *.: :*. *. *. :*:..*** :::* * . *:***** * .: :*. :.::::**::* *:** *:******:.*. **:****. **:******.***:* :****:*****:* ** *** :***::* .**:.** * **:*****. *:*:*.* ** *.. **. :* :. : *:: *:* * .:..* * . *:.*: :** : :* * *.*:******: * .* : :. : * *:.* * *****:** :::: ", "identical_positions": 244, "similar_positions": 200, "identity": "38.24%" }, { "cls_id": "homologset.agr.RGD:620908", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9M6-1", "uniprot_id": "G3V9M6_RAT", "id": "G3V9M6-1", "name": "Fibrillin-1", "aln": "MRRGGLLEVALAFTLLLESYTSHGADANLEAGSLKETRANRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQISPSCGSRSIQHCSIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVVSNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKFNEVSQKCEDIDECSTIPGVCDGGECTNTVSSYFCKCPPGFYTSPDGTRCVDVRPGYCYTTLTNGRCSNQLPQSITKMQCCCDVGRCWSPGVTVAPEMCPIRSTEDFNKLCSVPLVIPGRPDYPPPPLGPLPPVQPVP-GFPSGPVIPVPRPPPEYPYPSPSREPPKVLPFNVTDYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDIRGECIDVDECEKNPCTGGECINNQGSYTCHCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYRRGQCVKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDITGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFVYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSPESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSECCSSLGAAWGSPCTICQVDPICGKGYSRIKGTQCEDINECEVFPGVCKNGLCVNSRGSFKCECPSGMTLDATGRICLDIRLETCFLKYDDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPLRNSREYEELCPRGPGFATKDITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGICHNTEGSYRCECPSGHQLSPNISACIDINECELSANLCPSGRCVNLIGKYQCACNPGYHPTHDRLFCVDIDECSIMNGGCETFCTNSDGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKDGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDINECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYTCDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCELCPPVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYHADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRLTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNADQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKCAPGTCQNLDGSYRCICPPGYSLQNDKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSTGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPFGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILEGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCIDENECQTKPGICENGRCLNTLGSYTCECNDGFTASPTQDECLDNREGYCFSEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFEGTVAYKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTACVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTACIDNNECTSEINLCGSKGVCQNTPGSFTCECQRGFSLDQSGASCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHVCGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSSQAPCSYGCSNTEGGYLCGCPPGYLRIGQGHCVSGMGMGRGGPEPPASGEMDDNSLSPEACYECKINGYPKRGRKRRSTNETDASDIQDGSEMEANVSLASWDVEKPASFAFNISHINNKVRILELLPALTTLMNHNKYLIESGNEDGFFKINQKEGVSYLHFTKKKPVAGTYSLQISSTPLYKKKELNQLEDRYDKDYLSGELGDNLKMKIQILLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61554-1", "uniprot_id": "FBN1_MOUSE", "id": "Q61554-1", "name": "Fibrillin-1", "aln": "MRRGGLLEVALAFALLLESYTSHGADANLEAGSLKETRANRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQISPSCGSRSIQHCSIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVVSNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGMCQGGNCINTVGSFECKCPAGHKFNEVSQKCEDIDECSTIPGVCDGGECTNTVSSYFCKCPPGFYTSPDGTRCVDVRPGYCYTALANGRCSNQLPQSITKMQCCCDLGRCWSPGVTVAPEMCPIRSTEDFNKLCSVPLVIPGRPEYPPPPIGPLPPVQPVPPGYPPGPVIPAPRPPPEYPYPSPSREPPRVLPFNVTDYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDIRGECIDVDECEKNPCTGGECINNQGSYTCHCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYRRGQCVKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGTDINECALDPDICPNGICENLRGTYKCICNSGYEVDITGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFVYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSPESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSECCSSLGAAWGSPCTICQLDPICGKGFSRIKGTQCEDINECEVFPGVCKNGLCVNSRGSFKCECPNGMTLDATGRICLDIRLETCFLKYDDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPLRNSREYEELCPRGPGFATKDITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGICHNTEGSYRCECPPGHQLSPNISACIDINECELSANLCPHGRCVNLIGKYQCACNPGYHPTHDRLFCVDIDECSIMNGGCETFCTNSDGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKDGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYTCDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCELCPSVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRLTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNVDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKCAPGTCQNLDGSYRCICPPGYSLQNDKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSTGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPFGSGIIVGPDDSAVDMDECKEPDVCRHGQCINTDGSYRCECPFGYILEGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECAEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCIDENECQTKPGICENGRCLNTLGSYTCECNDGFTASPTQDECLDNREGYCFSEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFEGTVAYKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTACVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTACIDNNECTSDINLCGSKGVCQNTPGSFTCECQRGFSLDQSGASCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHVCGGASCHNTLGSYKCMCPTGFQYEQFSGGCQDINECGSSQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGGPEPPASSEMDDNSLSPEACYECKINGYPKRGRKRRSTNETDASDIQDGSEMEANVSLASWDVEKPASFAFNISHVNNKVRILELLPALTTLMNHNRYLIESGNEDGFFKINQKEGVSYLHFTKKKPVAGTYSLQISSTPLYKKKELNQLEDRYDKDYLSGELGDNLKMKIQILLH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35555-1", "uniprot_id": "FBN1_HUMAN", "id": "P35555-1", "name": "Fibrillin-1", "aln": "MRRGRLLEIALGFTVLLASYTSHGADANLEAGNVKETRASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYP--SREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYECKINGYPKRGRKRRSTNETDASNIEDQSETEANVSLASWDVEKTAIFAFNISHVSNKVRILELLPALTTLTNHNRYLIESGNEDGFFKINQKEGISYLHFTKKKPVAGTYSLQISSTPLYKKKELNQLEDKYDKDYLSGELGDNLKMKIQVLLH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** ***:**.*::** **************.:*****.*******************************************************************:***********.*********************************************************************:*****************************************************************:**********************:******************:*:****************************:*********:*:******************** ******************:***********:******:*****:**:*** *** *:*.** **.**** ** ** *****:***.************************************:***************:*************:*******************************************************************************************************************************************************:****:**************************************************:*********************************** **************************************:************************************.***************************************:**************:**:*******:***********:****************:******:**.*********************:*:**********************************:**: ***************:*************************************************************************************************************:*************.*********************:*** *******************.* *************************:**********************************************************************************************************************:*********************************************************:******************************************************:************************************************************* *****************************************************************:**.************************************************************************************************************************:********************************************************************************************************************************************:****************************************** ***************************************************:***********:********:********************:*:* **************************:***************************************:***************************************************************:************************:********************* ******************************************************************************************* *************************************:******************** ***************.*************:***************************************:****:******************************************************:*******************************************************************************:*********:********:********************:*:****************************************************:******************:*******************:***********************:****************.****.*.************************************:*:* ** *************.* *******:.*************** ***:*******************:***********************************:*******************:***", "identical_positions": 2753, "similar_positions": 96, "identity": "95.82%" }, { "cls_id": "homologset.agr.RGD:620909", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LYU8-1", "uniprot_id": "A0ABK0LYU8_RAT", "id": "A0ABK0LYU8-1", "name": "", "aln": "MEVEVERGKKKKQDWVMMGRWLRMRWRWTWGCIAGHQLFTLLWRGQSMVFRSPLDLYSSHFLLPNFADSHHCSLLLASSGGGSGAGGGGGAGGGGGGGGGNRAGGGGAGGAGGGGGGGGGGSRAPPEELSMFQLPTLNFSPEQVASVCETLEETGDIERLGRFLWSLPVAPGACEAINKHESILRARAVVAFHTGNFRDLYHILENHKFTKESHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQAIG----------------------------------PSGMRSLAEPGCPTHGSAES------------------------PSTAASPTTSVSSLTE-----------------------RADTGTSILSV----------------------------------------------------------------------------------TSSDSECDV------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62233-1", "uniprot_id": "SIX3_MOUSE", "id": "Q62233-1", "name": "Homeobox protein SIX3", "aln": "-----------------------------------------------MVFRSPLDLYSSHFLLPNFADSHHCSLLLASSGGGSGASGGG--GGAGGGGGGNRAGGGGAGGAGGGSGGGG--SRAPPEELSMFQLPTLNFSPEQVASVCETLEETGDIERLGRFLWSLPVAPGACEAINKHESILRARAVVAFHTGNFRDLYHILENHKFTKESHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQAIG----------------------------------PSGMRSLAEPGCPTHGSAES------------------------PSTAASPTTSVSSLTE-----------------------RADTGTSILSV----------------------------------------------------------------------------------TSSDSECDV------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95343-1", "uniprot_id": "SIX3_HUMAN", "id": "O95343-1", "name": "Homeobox protein SIX3", "aln": "-----------------------------------------------MVFRSPLDLYSSHFLLPNFADSHHRSILLASSGGGNGAGGGG--GAGGGSGGGNGAGGGGAGGAGGGGGGGS---RAPPEELSMFQLPTLNFSPEQVASVCETLEETGDIERLGRFLWSLPVAPGACEAINKHESILRARAVVAFHTGNFRDLYHILENHKFTKESHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQAIG----------------------------------PSGMRSLAEPGCPTHGSAES------------------------PSTAASPTTSVSSLTE-----------------------RADTGTSILSV----------------------------------------------------------------------------------TSSDSECDV------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q95RW8-1", "uniprot_id": "OPTIX_DROME", "id": "Q95RW8-1", "name": "Protein Optix", "aln": "-----------------------------------------------MAVGPTEGKQPPS---ESFSPTHHQ--IIAPS--------------------------------------------------PILAVPTLAFSAAQVEIVCKTLEDSGDIERLARFLWSLPVALPNMHEILNCEAVLRARAVVAYHVGNFRELYAIIENHKFTKASYGKLQAMWLEAHYIEAEKLRGRSLGPVDKYRVRKKFPLPPTIWDGEQKTHCFKERTRSLLREWYLQDPYPNPTKKRELAKATGLNPTQVGNWFKNRRQRDRAAAAKNRIQHSQNSSGMGCRSRRADGAASPTPSDSSDSDISLGTHSPVPSSLQLQHSPGSTSNGANDREESLSVDDDKPRDLSGSLPLPLSLPLPLASPTHTPPQLPPGYGGGAGAGPGGPLTGPGCLPPFKLDAATSLFSAGCYLQSFSNLKEMSQQFPIQPIVLRPHPQLPQSLALNGASGGPPLHHPAYAAAYSVECVPGGHGPPHPPPKLRINSPEKLNSTAVAAAASVGGGGGNQHHEPTTTGYHHSGQLMLHRPFSTSPELKHSAPEIT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. .. . .. .*: :** ::*.* .:: :*** **. ** **:***::******.********* . * : *::********:*.****:** *:******* *:************ ********.**************** ********************************:******:****.***********************:**. . **.:: .**..::*: : * . **** : ..*. : *:.**::*. *: : ..* ", "identical_positions": 179, "similar_positions": 63, "identity": "30.39%" }, { "cls_id": "homologset.agr.RGD:620910", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M5Q4-1", "uniprot_id": "F1M5Q4_RAT", "id": "F1M5Q4-1", "name": "Fibrillin-2", "aln": "MGRRRRLCLQPYFVWLGCVALWAQGTDGQPQPPPPKTLRPQPPPQQVRPAGAGSEGGFAGPEYRDE-GALAASRVRRRGQQEILRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISPTCGAKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSVVPGICETGDCSNTVGSYFCLCPRGFVTSTDGSRCIDQRTGTCFSGLVNGRCAQELPGRMAKAQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCLDGLPMGGIPGSSVSRPGGSGGN-------SNGYGPGGTGFLPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQT-IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCSHGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGRFQCICNAGFELTTDGENCVDHDECTTTNMCLNGMCINEDGSFKCVCKPGFVLAPNGRYCTDVDECQTPGICMNGHCINNEGSFRCDCPPGLAVGVDGRVCVDTHMRSTCYGEIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSGGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDVNECESNPCVNGACRNNLGSFHCECSPGSKLSSTGLICIDSLKGTCWLNIQDNRCEVNINGATLKSECCATLGTAWGSPCERCELDAACPRGFARIKGVTCEDVNECEVFPGVCPNGRCVNNKGSFHCECPEGLTLDGTGRVCLDVRMEHCFLKWDEDECVHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGPGFANRGDILTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFDCECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCIDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCSDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMRTCIDVNECDLNPNICMFGECENTKGSFICHCQLGYSVKKGATGCTDVDECEIGAHNCDMHASCLNVPGSFKCSCREGWVGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEVGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEETRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGN-IPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICNNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCICPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKD-DEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYSGVRCVDTDECSIGNPCGNGTCANVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPVGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTMCQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYATDGRDIDECKVMPSLCTNGQCVNTMGSFRCFCKVGYTTDISGTACVDLDECSQSPKPCNFICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDASGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYVQHYQWNQCVDENECSNPGACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCSYGCSNTEGGYLCGCPPGYFRVGQGHCVSGMGFNKGQYLSVDSEAEDDENALSPEACYECKINGYAKKDGRRKRSAPEPEPASAEEQISLESVAMDSPVNMKFNLSGLGSKEHILELVPAIEPLNNHIRYVISQGNDDGVFRIHQR-NGLSYLHTAKKKLTPGTYTLEITSVPLYGKKELRKLEERNEDSYLLGVLGEALRMRLQIQLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61555-1", "uniprot_id": "FBN2_MOUSE", "id": "Q61555-1", "name": "Fibrillin-2", "aln": "MGRRRRLCLQPYFVWLGCVALWAQGTDGQPQPPPPKTLRPQPPPQQVRPAVAGSEGGFMGPEYRDE-GAVAASRVRRRGQQEILRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISPTCGAKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSVIPGVCETGDCSNTVGSYFCLCPRGFVTSTDGSRCIDQRAGTCFSGLVNGRCAQELPGRMAKAQCCCEPGRCWSIGTIPEACPVRGSEEYRRLCLDGLPMGGIPGSSVSRPGGTGST-------GNGYGPGGTGFLPIPGDNGFSPGVGGAGVGAGGQGPIITGLTILNQT-IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCSNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCVCKPGFILAPNGRYCTDVDECQTPGICMNGHCINNEGSFRCDCPPGLAVGVDGRVCVDTHMRSTCYGEIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGIGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDVNECESNPCVNGACRNNLGSFHCECSPGSKLSSTGLICIDSLKGTCWLNIQDNRCEVNINGATLKSECCATLGAAWGSPCERCELDAACPRGFARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEHCFLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGPGFANRGDILTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNNGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNPNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNVPGSFKCSCREGWVGNGIKCIDLDECANGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENTNLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEVGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEETRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGN-IPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICNNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVRSENCIDINECDEDPNICLFGSCTNTPGGFQCICPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKD-DEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECTCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPVGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTMCQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYATDGRDIDECKVMPSLCTNGQCVNTMGSFRCFCKVGYTTDISGTACVDLDECSQSPKPCNFICKNTKGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDASGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYVQHYQWNQCVDENECSNPGACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCSYGCSNTEGGYLCGCPPGYFRVGQGHCVSGMGFNKGQYLSVDAEAEDDENALSPEACYECKINGYTKKDGRRKRSAQEPEPASAEEQISLESVAMDSPVNMKFNLSGLGSKEHILELVPAIEPLNNHIRYVISQGNEDGVFRIHQR-NGLSYLHTAKKKLAPGTYTLEITSIPLYGKKELRKLEEHNEDDYLLGVLGEALRMRLQIQLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35556-1", "uniprot_id": "FBN2_HUMAN", "id": "P35556-1", "name": "Fibrillin-2", "aln": "MGRRRRLCLQLYFLWLGCVVLWAQGTAGQPQPPPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREE-GAAVASRVRRRGQQDVLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQT-IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGN-IPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKD-DEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLDTEVDE-ENALSPEACYECKINGYSKKDSRQKRSIHEPDPT-AVEQISLESVDMDSPVNMKFNLSHLGSKEHILELRPAIQPLNNHIRYVISQGNDDSVFRIHQR-NGLSYLHTAKKKLMPGTYTLEITSIPLYKKKELKKLEESNEDDYLLGELGEALRMRLQIQLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B786-1", "uniprot_id": "A0ACD6B786_DANRE", "id": "A0ACD6B786-1", "name": "", "aln": "MGVWK----------LANVVLWWA---------------------AVHSVQGQGDGDIQASRFTGKPEGEVQQRVRRRGQ-ESLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGHLAPSCGAAAVQSCSVRCMNGGMCNEDACSCQKGYTGTHCGQPVCESGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLSGIVCTKTLCCATIGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAVPGLCAGGNCINTVGSYECKCPAGHRQSETNQKCEDIDECATISGVCDGGECTNTAGSYVCTCPRGYITSTDGSRCVDHRIGTCFSSLANGRCASELSGQYTKMQCCCDTGRCWALGHIPEMCPVRGSDEYRRLCIQRLPFG--TGNGGIIHDGNGGLN------IGGYGKGPS--QNGNGGGGYIYGSEHTFTNGNGNGGQKIQISQLNETTIDVCKHFTNLCLNGRCIPTPTSYRCECNMGYRQDVRGECIDVDECVSNPCVNGDCVNTQGSYHCKCHEGYQGTPTKQACIDIDECIVNGVMCRNGRCVNTDGSFQCICNAGFEISPDGKNCIDHDECATTNMCLNGMCINEDGSFKCICKPGFALAPNGRYCTDIDECHTSGICMNGRCVNTEGSFRCECPPGLAIDVDGRVCVDTHMRTTCYGAIKMGVCSRPFPGAVTKSECCCANPEHGFGEPCQPCPAFNSAEFQAVCSSGPGITTDGRDINECALDPDICQNGICENLRGSYRCICNIGYESDASGKNCVDINECLVNRLLCDNGMCRNTPGSYTCSCPKGFSFKADSETCEDINECDSNPCINGICRNIAGSFNCECSHGSKLDSTNTVCVDSMKGTCWLNIQDGRCEVNINGATLKSECCSTLGAAWGSPCERCEIDPACSKGFGRMKGLVCEDINECEVFPGVCTNGRCVNTQGSFRCECPEGLTLDGAGRTCVDVRSEQCYMKWDEDECVEPLPGRYRVDMCCCTVGAAWGVDCEACPKPNTNEFKTICPRGPGIANRGDILTGRPFYKDVNECKVFRGLCTHGTCRNTIGSFKCRCDSGFALTMEERNCTDIDECTISPDLCGHGVCVNTPGSFECECFDGYESGFMMMKNCMDIDECERDPLLCRGGTCLNTEGSYECDCPPGHQLSTEASACEDVNECQLSDNLCKHGQCVNMVGTYQCSCETGYQVTPDRQGCVDIDECTIMNGGCDTHCTNSEGSYECSCSEGYALMPDLRTCADIDECEDTPDICDGGQCTNIPGEYRCLCYDGFMASMDMRTCIDVNECDLNPNICLHGDCENTKGSFICHCQLGYFVKKGSTGCTDVDECEIGAHNCDLHAACVNAPGSFKCRCRDGWEGDGIKCIDVDECVTEEHNCNPNAECLNTPGSYRCSCKEGFNGDGFSCSDMDECADNVNLCENGQCLNAPGGYRCECEMGFTPTEDSKACQDIDECNFQNICVFGSCQNLPGMFRCVCDYGYELDRSGGNCTDINECFDPVNCINGVCVNLPGSYLCNCPPDFELNPSGVGCVDTRVGNCFLDTLDRGDGGISCSAEIGVGVTRASCCCSLGGAWGNPCELCPSVNSTEYKTLCPGGEGFRPNPITVILEDIDECQELPGLCQGGNCVNTFGSFQCECPAGYYLNEETRICEDIDECTAHIGICGPGTCYNTLGNYTCVCPPEYMQVNGGNNCMDMRKSVCYRNFN-DTCENELSFNMTKKMCCCAYNVGKAWNRPCEACPTPATSEYQLLCGNQAPGFIIDIHTGKPIDIDECREIPGICANGVCINQIGSFRCECPMGFSYNNILLICEDIDECNSGDNLCQRNANCINIPGSYRCECSAGFKLSPSGACIDRNECQEIPNVCSHGECIDTQGSFRCLCHNGFKTTPDQTMCMDIDECDRQPCGNGTCKNTVGSYNCLCFPGFELTHNNDCMDIDECSVHASQVCRNGQCINNMGSFKCLCLDGYNLTPDGKNCVDINECVTLPGACQPGTCQNLDGSFRCICPPGYEVQNDKCVDINECNVEPNICQFGTCKNTPGSFQCICQPGFVLSDNGRRCFDTRESFCFTRFEAGKCSVPKPRNTTKAKCCCSLLPGEGWGDPCELCPRDTEEAAFHTLCPYGHEAVP-KPEGREDMNECVENPEICGNGLCINTDGSFRCECPFGYNLDYTGVNCVDTDECSIGNPCGNGTCSNVPGGFECSCQEGFEPGPMMTCEDINECAVNPLLCAFRCVNTFGSYECMCPTGYVLRDDNRMCRDQDECAEGLDDCASRGMACKNQIGTFMCICPPGMTRRPDGEGCMDLNECRSKPGICKNGRCVNTVGSYRCECNEGFEASATGTECIDNRKGFCFTEVLQTMCQQSSTNRNTVTKSECCCNGGRGWGSLCELCPLPGTIQYKKMCPLGPGYTTDGRDINECEVMPNLCKNGQCINSVGSFRCHCNVGYTNDFTGTSCIDMDECSQSPKPCNFLCKNTEGSYLCSCPRGYILQPDGKTCKDLDECSTKQHNCQFLCVNTIGGFTCKCPSGFTQHQTACIDNNECSNQPNICGSRASCLNSPGSFNCECQKGFSLDATGLNCDDVDECGGNHRCQHGCQNMMGGYRCGCPQGYVQHYQWNQCVDENECTGNQVCGSASCYNTLGSYKCVCPSGFDFEASAGGCQDVNECSMGNNPCSYGCSNTDGGYLCGCPGGFYRAGQGHCINGVGFQG----QFGSEGEDDEESLSPEACYECKINGDLGKKGRHRRNADDNELK---ETVSMASMDIQTSIPMNLSLAQLLNKEPLLELLPALEPLEHHVRYVITHGNQGEHFRILERRDGKSVLRLGRRPPAPGLYRLEIASLRLFGPRKLQQMEDQHDSDYLLGEIGDALRIKLHIHLH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : *. *.** *:.. . .:*.: ...: : . . .******* : *****************************************************:::.:**: ::*.********* * :* *.***** **:*******.***********************************************:****************************:***********************:**:* **********:**:*****:****.*********: :.*:*: *:*:**.***.* ****::********:*:* * ***.*.*****.**.*: :* ****:.****.:* *** ******:******:: **:* .*.. .*.*. .*** * : *..*: * : ....*:* :: **:* **:***.:*********** :**********:**..*:*******.**** :****** ***:**** *:* ************** ***:*:********* **********::.**:**:*****:*******************:***** **********:***:*.******:*:*.******:******:.:***********:**** ** *** *****************::*********** *****:.:**.* ***.*************** ************* ** ***.****:**:**:************:********:*:** *: *::::*****:***:****:** *** ***:**** ****.**. :*:**:**********.****************:***:**********:*.**.:*:.*:**:.***:**********.******.:***:***********:**.*:*:* *:*::*******:.*:**::*:* ***:******.:** ****.*:*::*:****.*:*****:*********:****.* *:**:*.************:.**** ************ ******* *:********:****:********************:*********:*****::**** **:**.. . * *:***.******::*:****:*******:.***.******* ***** ********:********************* *:********:.******************************:***********.***:.*:**************** ****:*****************:**:*:* ****** **:** *:******:*** . *:*. **:*:********:*.***.****:***:****:* **********.**.***********:.**::*******.********:*:******:*:** ******:*******:** **:**:**:*** ** * *******:***:******.*****:*. ****.:**.:*:****:*:******* ******* **.****** ***************:********************:*********** ****.*:********** ** *:***************:***********:********.***.:* ******.**:**:****:********:***.****.*:::: :*** *** :******.:*****:*********************** *****::**:*******..*********:*** ********:*******.***:***** ********* *:* ***::*:*:****:: *******:***:*:******************:***********:****** . .******:*:*::******* :**:********:* ****:***:*.*******:*************:.::*:*****: :**** **:*.****.***:* ****************:*****.** *******. ********** :*************:* :*.**: ****** :** : ***:***:*.* **.** *************:******:**.******************:** *.***.*:*********.******** *********:******** ** **.**:*::**:* *******.** **** *** ************:********:* ****:*****:****** :***********::*::****:***:*:**:*****:** :*:.** ********:****** ********* ****:** ****:******:**:***.**.****:*::*****.*:****.*::**:*:*:***********::****:*** *******:** ***********.*************:********.*****:*********..**.:**::. * *:****.****:******:****:*****.***********::***********:**************:. .***************.*****.*: :..*:****** .:***.******:******** *::*.*****:.*:**: ...:* :: *::************* *..*::*. : : * :*: *: :::.: *::.*: * .** :*** **::**::*:****::**:. *** :* :* * *: .:: ** * ***:*: *: ::*:::*: ::..**** :*:***::*:*:*:", "identical_positions": 2143, "similar_positions": 516, "identity": "73.42%" }, { "cls_id": "homologset.agr.RGD:620911", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97685-1", "uniprot_id": "NFASC_RAT", "id": "P97685-1", "name": "Neurofascin", "aln": "-MARQQAPPWVHVALILFLLSLGGAIEIPMDPSIQNELTQPPTITKQSVKDHIVDPRDNILIECEAKGNPAPSFHWTRNSR-FFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEP----ITQDKRVSQGHNGDLYFSNVMLQDMQTDYS--CNARFHFTHTIQQKNPFTLKVLT----------------TRGVAERTPSFMYPQGTSSSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS-DKAKFENFNKALRITNVSEEDSGEYFCLASNKMG-SIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWLVNGDPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVAKRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIG--NRMKKE-DDSLTIFGVAERDQGSYTCMASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDDNNSPITDYVVQFEEDQFQPGVWHDHSKFPGSVNSAVLHLSPYVNYQFRVIAVNEVGSSHPSLPSERYRTSGAPPESNPSDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRETWNNVTVWGSR---YVVGQTPVYVPYEIRVQAENDFGKG-PEPETVIGYSGEDLP-------------------------------------------------------------------------------------------------------------SAPRRFRVRQPNLETINLEWDHPEHPN---GILIGYTLRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQVGSGEAATEESPTPPNEATP-----------------TAAPPTLPPTTVGTTGLVSSTDATALAATSEATTVPIIPTVVPTTVATTIATTTTTTAAATTTTTTESPPTTTTGTKIHETAPD------EQSIWNVTVLPNSKWANITWKHNFRPG--TDFVVEY-IDSNHTKKTVPVKAQAQPIQLTDLFPGMTYTLRVYSRD----NEGISSTVITFMTSTAYTNNQTDIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYS-------DEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVRKDKEETEGNESSEATSPVNAIYSLA---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q810U3-1", "uniprot_id": "NFASC_MOUSE", "id": "Q810U3-1", "name": "Neurofascin", "aln": "-MARQQAPPWVHIALILFLLSLGGAIEIPMDPSIQNELTQPPTITKQSVKDHIVDPRDNILIECEAKGNPAPSFHWTRNSR-FFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEP----ITQDKRVSQGHNGDLYFSNVMLQDMQTDYS--CNARFHFTHTIQQKNPFTLKVLT----------------TRGVAERTPSFMYPQGTSSSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS-NKAKFENFNKALRITNVSEEDSGEYFCLASNKMG-SIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSARNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVAKRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIG--NRMKKE-DDSLTIFGVAERDQGSYTCMASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDDNNSPITDYVVQFEEDQFQPGVWHDHSRFPGSVNSAVLHLSPYVNYQFRVIAVNEVGSSHPSLPSERYRTSGAPPESNPSDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRETWNNVTVWGSR---YVVGQTPVYVPYEIRVQAENDFGKG-PEPDTIIGYSGEDLP-------------------------------------------------------------------------------------------------------------SAPRRFRVRQPNLETINLEWDHPEHPN---GILIGYILRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQVGSGEAATEESPAPPNEATP-----------------TAAPPTLPPTTVGTTGLVSSTDATALAATSEATTVPIIPTVVPTTVATTIATTTTTTAATTTTTTTESPPTTTAGTKIHETAPD------EQSIWNVTVLPNSKWANITWKHNFRPG--TDFVVEY-IDSNHTKKTVPVKAQAQPIQLTDLFPGMTYTLRVYSRD----NEGISSTVITFMTSTAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYS-------DEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94856-1", "uniprot_id": "NFASC_HUMAN", "id": "O94856-1", "name": "Neurofascin", "aln": "-MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSR-FFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEP----ITQDKRVSQGHNGDLYFSNVMLQDMQTDYS--CNARFHFTHTIQQKNPFTLKVLT----------------TRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS-DKAKFENFNKALRITNVSEEDSGEYFCLASNKMG-SIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIG--NRMKKE-DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSR---YVVGQTPVYVPYEIRVQAENDFGKG-PEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQA--SFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPN---GIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATP-----------------TAAPPTLPPTTVGATGAVSSTDATAIAATTEATTVPIIPTVAPTTIATTTTVATTTTTTAAATTTTESPPTTTSGTKIHESAPD------EQSIWNVTVLPNSKWANITWKHNFGPG--TDFVVEY-IDSNHTKKTVPVKAQAQPIQLTDLYPGMTYTLRVYSRD----NEGISSTVITFMTSTAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYS-------DEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U331-1", "uniprot_id": "A0AB32U331_DANRE", "id": "A0AB32U331-1", "name": "Neural cell adhesion molecule L1", "aln": "MWTQRRWAALAVLSIISLLSEEAAAIEVPLDPKIQQELKQPPTIVKQSLKDYIVDPRDNIIIECEAKGNPVPTFQWRRNGK-FFNVGKDPRVTMRSRSGTLEI--RSSGKPEDYEGEYQCFASNNLGTAISNKILLRVSKSPLWPKEVLEPVTVREGSPLVLACNPPPGLPPPETFWMDSFIMP----IAQDRRVSMGLNGDLFFSNVLAKDAKTDYS--CNARFEFTHTIQQKNPYTLKVQTKEPYNDTFLNSTDVYGVRNIPETQPTFLSPTGLSSTKMVLRGEELLLECIAAGVPTPTITWSKRGGDLPT-KKVRIGNFEKTLRILNVSEEDIGSYTCMASNRIG-SIRHTVEVQVKAAPFWLEKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIESSLPNPNRRVLDDTIIFETVQFESSAVYQCNASNEHGYLLANAFVSVLDMAPRMLGPKNQLIKVIENNRTFLECPFFGSPLPLLRWFKNGLGSGLDGGHYRLYHNGTLEIKQARTEDQGTYTCVASNILGKMENQVRLEVKEPTRIVRAPEHKTEPRGTTVRFDCRVKHDPSLPATVTWLKDEKPLSFSWIGRLKKD-DESLTIYNVNPDDGGTYTCTAKTEIDEDTASARLTVTENDSSSASNRSAS-AGRPDPPQDLELSDPSARSVRLTWVPGNENNSPVTHFLVQFEEDRWEPGKWQNLSIYDWNLNSVNLQLSPFVNYQFRVIAINAVGQSQPSHPSARYQTSGAPPDVVPSGLKGWGSKKNNMEITWQAMQNTERNGPNLRYVLSWRRKDTEEEWNNITTAKTK---HVVHNTDTYVPYEIKIQAVNDFGHG-PESNMVIGYSGEDKPSAAPTDLRVSKINSTKVNIHWEPVEQSSVNGEFKEYKLYYWREASLIKGLKVNKTKLQKGFFTTAEHPSGILTELYPYSKYKMYMVVANREHEGPQSNTVEFYTKEGEPGAPKYFRILR-HTDVVHLKWDKPLEPN---GVLIGYTLQYHTVNGTQAGERKVQSFPPNVTEYVMNLPHRFTRFKFFLAARTQVGAGEVYAVESPHFTNEGTPDTDSTVVAVNFTDGLMFEIPPPPLPPSTD-PNPTIFTPEPTPPVPTTAAPTKPTTTTTTTTTTTTTSTTTTTTTTTTTTTTTTAASTTVAPVRPVPPKTVDWKMLAPNVKIWNLTVDANNDNANVSWKHNFSVDS-SKFVVEFTLDSNGSMTSIQVNQQPH-IKLAGLVAGAKYRLRVYSHE----HNSISSDYVTFETGRAYKE-QEDIATQGWFIGLMCAVALLVLILLIVCFIKRSRGGKYPVREKKDLPLDPVDHKDQDGSFDYQSLERESSDEDNKPLQGSQTSLDGNVK--ESDDSLVDYGEGGDGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20241-1", "uniprot_id": "NRG_DROME", "id": "P20241-1", "name": "Neuroglian", "aln": "---MWRQSTILAALLVALLCAGSAESKGNRPPRITKQPAPGELLFKVAQQNKESD--NPFIIECEADGQPEPEYSWIKNGKKFDWQAYDNRMLRQPGRGTLVITIPKDED----RGHYQCFASNEFGTATSNSVYVRKAELNAFKDEAAKTLEAVEGEPFMLKCAAPDGFPSPTVNWMIQESIDGSIKSINNSRMTLDPEGNLWFSNVTREDASSDFYYACSATSVFRSEYKIGNKVLLDVKQMG---------------VSASQNKHPPVRQYVSRRQSLALRGKRMELFCIYGGTPLPQTVWSKDGQRIQWSDRITQGHYGKSLVIRQTNFDDAGTYTCDVSNGVGNAQSFSIILNVNSVPYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTPNPRRTVTDNTIRIINLVKGDTGNYGCNATNSLGYVYKDVYLNVQAEPP-TISEAPAAVSTVDGRNVTIKCRVNGSPKPLVKWLR--ASNWLTGGRYNVQANGDLEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVVKEHTRITQEPQNYEVAAGQSATFRCNEAHDDTLEIEIDWWKDGQSIDFEAQPRFVKTNDNSLTIAKTMELDSGEYTCVARTRLDEATARANLIVQDVPNAPK----------------LTGITCQADKAEIHWEQQGDNRSPILHYTIQFNTSFTPASWDAAYEKVPNTDSSFVVQMSPWANYTFRVIAFNKIGASPPSAHSDSCTTQPDVPFKNPDNVVGQGTEPNNLVISWTPMPEIEHNAPNFHYYVSWKRDIPAAAWENNNIFDWRQNNIVIADQPTFVKYLIKVVAINDRGESNVAAEEVVGYSGEDRP------------------------------------------------------------------------------------------------------------LDAPTNFTMRQITSSTSGYMAWTPVSEESVRGHFKGYKIQTWTENEGEEGLREIHVKGDTHNALVTQFKPDSKNYARILAYNGRFNGPPSAVIDFDTPEGVPSPVQGLDAYPLG-SSAFMLHWKKPLYPNGKLTGYKIYYEEVKESYVGERREYDPHITDPRVTRMKMAGLKPNSKYRISITATTKMGEGSEHYIEKTTLKDAVNVAPATPSFSWEQLPSDNGLAKFRINWLPSTEGHPGTHFFTMHRIKGETQWIRENEEKNSDYQEVGGLDPETAYEFRVVSVDGHFNTESATQEIDTNTVEGPIMVANETVANAGWFIGMMLALAFIIILFIIICIIRRNRGGKYDVHDR-ELANGRRDYPEEGGFHEYS------QPLDNKSAGRQSVSSANKPGVESDTDSMAEYGDGDTGQFTEDGSFIGQYVPGKLQPPVSPQPLNNSAAAHQAAPTAGGSGAAGSAAAAGASGGASSAGGAAASNGGAAAGAVATYV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :: * .. : * * :: : * : :: * : ::*****.*:* * : * :*.: * . * *: : *** * .. .*.***** *::*** ** : :: :: : .* ..: . ** *: * * .* *:*.* ** . :: *:: . :*:*:**** :* .:*: *.* * : * *.* . .: . : .:.*** : * ** .*.* * .* * * : .: :: *:* * :.. :* * * * .** :* : .:: :.*::.*:: .:* * .*. : *** * *:*.:.*: **.*::.: ***.* * .:** : . . * **::*. **: :.::.* .* :. : .: ... :.* . *** * ::*:: .. * **.*.: ** ***: .* * *** * * :*: : : * **: *** : *:. * :. : *. ** :* : * ** :.: : *: * *:**** . * * *** * *.:*: * * * * :. * ...: * . *.**: .: :**: . .. . . .* :::**:.** *****.* :* * ** * *. * *..: * *:. **: *:* .* . .**::* :.*:* . *:* . : *: : .:* * *:: * ** *.. .: ::****** * .** * : : .. * : * : ** :: . * : * : :. . . : ..: *: . :... . : . :* * * . . . . .. : :. : ::**. . : : . . ::. . .:.* . :.*.. . :..: : :.. :: .* . * :** * : :. :. * . . : :*. *****:* *:*:::::::*:*:*:*.***** *::: ::. . * ::.* .:*. ***. ...* .. .. **:.:**:*. ***.*********. * : .. : .::::. :* : . ", "identical_positions": 293, "similar_positions": 370, "identity": "20.05%" }, { "cls_id": "homologset.agr.RGD:620912", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99P39-1", "uniprot_id": "NFS1_RAT", "id": "Q99P39-1", "name": "Cysteine desulfurase", "aln": "--------MLLRVAWRR----ASLAATSVALRRSSVPTRGLRLR------------VVDHAPHSAVPS------EAEAVL-----------------RPLYMDVRATTPLDPRVLDAMLPYLVNYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLVTTQTEHKCVLDSCRSLEAEGFRVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGQICSSRKLYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKLYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACELAQQEMEYDHKRISKLAERLIQKIMKNLPDVVMNGDPKQHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTVQKCIHHVKRLREMSPLWEMVQDGIDLKSIKWTQH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1J3-1", "uniprot_id": "NFS1_MOUSE", "id": "Q9Z1J3-1", "name": "Cysteine desulfurase", "aln": "MVGSVAGNMLLRAAWRR----ASLAATSLALGRSSVPTRGLRLR------------VVDHGPHSPVHS------EAEAVL-----------------RPLYMDVQATTPLDPRVLDAMLPYLVNYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLVTTQTEHKCVLDSCRSLEAEGFRVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGQICSSRKVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKLYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACELAQQEMEYDHKRISKLAERLVQNIMKNLPDVVMNGDPKQHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTAEKCIHHVKRLREMSPLWEMVQDGIDLKSIKWTQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y697-1", "uniprot_id": "NFS1_HUMAN", "id": "Q9Y697-1", "name": "Cysteine desulfurase", "aln": "--------MLLRAAWRR----AAVAVTAAPGPKPAAPTRGLRLR------------VGDRAPQSAVPADTAAAPEVGPVL-----------------RPLYMDVQATTPLDPRVLDAMLPYLINYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLITTQTEHKCVLDSCRSLEAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGRICSSRKVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKIYGPKGVGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACEVAQQEMEYDHKRISKLSERLIQNIMKSLPDVVMNGDPKHHYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTVEKCIQHVKRLREMSPLWEMVQDGIDLKSIKWTQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKD3-1", "uniprot_id": "NFS1_DROME", "id": "Q9VKD3-1", "name": "Cysteine desulfurase, mitochondrial", "aln": "-MQKVLGRIQAQVLRSR----ATNALANVVRHEATSSRTAAKPA------------ATSKEFRERQVRFN--IKNEQTEG-----------------RPLYLDAQATTPMDPRVLDAMLPYLTNFYGNPHSRTHAYGWETESAVEKAREQVATLIGADPKEIIFTSGATESNNIAVKGVARFYGTKKRHVITTQTEHKCVLDSCRALENEGFKVTYLPVLANGLIDLQQLEETITSETSLVSIMTVNNEIGVRQPVDEIGKLCRSRRVFFHTDAAQAVGKVPLDVNAMNIDLMSISGHKIYGPKGVGALYVRRRPRVRLEPIQSGGGQERGLRSGTVPAPLAVGLGAAAELSLREMDYDKKWVDFLSNRLLDRISSALPHVIRNGDAKATYNGCLNLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYVLRAIGTDEDLAHSSIRFGIGRFTTVEEVDYTADKCIKHVERLREMSPLWEMVQEGIDLKTIQWSQH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25374-1", "uniprot_id": "NFS1_YEAST", "id": "P25374-1", "name": "Cysteine desulfurase", "aln": "MLKSTATRSITRLSQVYNVPAATYRACLVSRRFYSPPAAGVKLDDNFSLETHTDIQAAAKAQASARASASGTTPDAVVASGSTAMSHAYQENTGFGTRPIYLDMQATTPTDPRVLDTMLKFYTGLYGNPHSNTHSYGWETNTAVENARAHVAKMINADPKEIIFTSGATESNNMVLKGVPRFYKKTKKHIITTRTEHKCVLEAARAMMKEGFEVTFLNVDDQGLIDLKELEDAIRPDTCLVSVMAVNNEIGVIQPIKEIGAICRKNKIYFHTDAAQAYGKIHIDVNEMNIDLLSISSHKIYGPKGIGAIYVRRRPRVRLEPLLSGGGQERGLRSGTLAPPLVAGFGEAARLMKKEFDNDQAHIKRLSDKLVKGLLS-AEHTTLNGSPDHRYPGCVNVSFAYVEGESLLMALRDIALSSGSACTSASLEPSYVLHALGKDDALAHSSIRFGIGRFSTEEEVDYVVKAVSDRVKFLRELSPLWEMVQEGIDLNSIKWSGH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: : . . : . : . : **:*:* :**** ******:** : . ******.**:****:::*:*.** :**.:*.***:*************:.:***.*** . *:*::**:*******::.*:: ***.**:* * .*:***::** :* .:*.***:*:******* **: *** :* ..:::******** **: :*** *:***:***.**:*****:**:*:*******:*.: ********:****:..**..*:* *..: :*:: *: :. *:::*:. : . .. **... * **:*:**************:*:*******************:*:*.*: *************:* *****... .:*: ***:********:****::*:*: *", "identical_positions": 242, "similar_positions": 122, "identity": "48.59%" }, { "cls_id": "homologset.agr.RGD:620913", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38532-1", "uniprot_id": "HSF1_MOUSE", "id": "P38532-1", "name": "Heat shock factor protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MDLAVGPGAAGP----------SNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKR------------------------------------KVTSVSTLKSEDIKIR--------------QDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNR-ILGVKRKIPLMLSDS---------------------NSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSS------------------------------GPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPR-----------------------------------------VLEASP-GRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTG----------------------------------------AQAPALPTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTS-----------HGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQ----EPPRPIEAENSN-------------PDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MAF1-1", "uniprot_id": "F1MAF1_RAT", "id": "F1MAF1-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MDLAVGPGAAGP----------SNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKR------------------------------------KVTSVSTLKSEDIKIR--------------QDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNR-ILGVKRKIPLMLSDS---------------------SSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSS------------------------------GPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKEEPPSPPHSPR-----------------------------------------VLEASP-GRPASMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTG----------------------------------------AQAPAPPAPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTS-----------HGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQ----EPPRPIEAENSN-------------ADSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00613-1", "uniprot_id": "HSF1_HUMAN", "id": "Q00613-1", "name": "Heat shock factor protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MDLPVGPGAAGP----------SNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKR------------------------------------KVTSVSTLKSEDIKIR--------------QDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNR-ILGVKRKIPLMLNDS---------------------GSAHSMPKYSRQFSLEHVHGSGPYSAPSPAYSSSSLYAPDAVASS------------------------------GPIISDITELAPASPMASPGGSIDERPLSSSPLVRVKEEPPSPPQSPR-----------------------------------------VEEASP-GRPSSVDTLLSPTALIDSILRESEPAP-ASVTALTDARGHTDTE-----------------------------------GRPPSPPPTSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLSS-----------HGFSVDTSALLDLFSPSVTVPDMSLPDLDSSLASIQELLSPQ----EPPRPPEAENSS-------------PDSGKQLVHYTAQPLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22813-1", "uniprot_id": "HSF_DROME", "id": "P22813-1", "name": "Heat shock factor protein", "aln": "--------------------------------------------------------------------------------------------------------------------MSRSRSSAKAVQFKHESEEEEEDEEEQLPSRRMHSYGDAAAIG----------SGVPAFLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNMYGFHKITSIDNGGLR-FDRDEIEFSHPFFKRNSPFLLDQIKR------------------------------------KISNNKNG-DDKGVLK--------------PEAMSKILTDVKVMRGRQDNLDSRFSAMKQENEVLWREIASLRQKHAKQQQIVNKLIQFLITIVQPSRNMSGVKRHVQLMINNTPEIDRART------TSETESESGGGPVIHELREELLDEVMNPSPAGYTAASHYDQESVSPPAVERPRSNMSISSHNVDYSNQSVEDLLLQGNGTAGGNILVGGAASPMAQSVSQSPAQHDVYTVTEAPDSHVQEVPNSPPYYEEQNVLTTPMVREQEQQKRQQLKENNKLRRQAGDVILDAGDILVDSSSPKAQRTSIQHSTQPDVMVQPMIIKSEPENSSGLMDLMTPANDLYSVNFISEDMPTDIFEDALLPDGVEEAAKLDQQQKFGQSTVSSGKFASNFDVPTNSTLLDANQASTSKAAAKAQASEEEGMAVAKYS-----GAENGNNRDTNNSQLLRMASVDELHGHLESMQDELETLKDLLRGDGVAIDQNMLMGLFNDS-------------DLMDNYGLSFPNDSISSEKKAPSGSELISYQPMYDLSDILDTDDGNNDQEASRRQMQTQSSVLNTPRHEL----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10961-1", "uniprot_id": "HSF_YEAST", "id": "P10961-1", "name": "Heat shock transcription factor", "aln": "MNNAANTGTTNESNVSDAPRIEPLPSLNDDDIEKILQPNDIFTTDRTDASTTSSTAIEDIINPSLDPQSAASPVPSSSFFHDSRKPSTSTHLVRRGTPLGIYQTNLYGHNSRENTNPNSTLLSSKLLAHPPVPYGQNPDLLQHAVYRAQPSSGTTNAQPRQTTRRYQSHKSRPAFVNKLWSMLNDDSNTKLIQWAEDGKSFIVTNREEFVHQILPKYFKHSNFASFVRQLNMYGWHKVQDVKSGSIQSSSDDKWQFENENFIRGREDLLEKIIRQKGSSNNHNSPSGNGNPANGSNIPLDNAAGSNNSNNNISSSNSFFNNGHLLQGKTLRLMNEANLGDKNDVTAILGELEQIKYNQIAISKDLLRINKDNELLWQENMMARERHRTQQQALEKMFRFLTSIVPHLDPKMIMDGLGDPKVNNEKLNSANNIGLNRDNTGTIDELKSNDSFINDDRNSFTNATTNARNNMSPNNDDNSIDTASTNTTNRKKN---------------IDENIKNNNDIINDIIFNTNLANNLSNYNSNNNAGSPIRPYKQRYLLKNRANSSTSSENPS--------------------------------------------LTPFDIESNNDRKISEIPFDDEEEEETDFRPFTSRDPNNQTSENTFDPN-----------------------------RFTMLSDDDLKKDSHTNDNKHNESDLFWDNVHRNIDEQDARLQNLENMVHILSPGYPNKSFNNKTSSTNTNSNMESAVNVNSPGFNLQDYLTGESNSPNSVHSVPSNGSGSTPLPMPNDNDTEHASTSVNQGENGSGLTPFLTVDDHTLNDNNTSEGSTRVSPDIKFSATENTKVSDNLPSFNDHSYSTQADTAPENAKKRFVEEIPEPAIVEIQDPTEYNDHRLPKRAKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * .. ***: *** ::.* .. ** *: .*:** : :: :*.:::** :**.*:***:*******::*: :..*.: . *. :*.: * *. **::* * :::. .. .: :: : :: :* ::: :: .* :.. : ::::** **:* *::* **: ::*:::** ::* :. :.: . .. : *: : . .. . . . :. :. . *: :. :. . .. : : . :.. :* :. : . : : ::: :. . . . . : . : * :: .:. .: : * : . .. .* * . . : : . *.. . . : . . .: . :. : .:. : . : : :: : ", "identical_positions": 64, "similar_positions": 175, "identity": "6.95%" }, { "cls_id": "homologset.agr.RGD:620914", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21677-1", "uniprot_id": "TFE2_RAT", "id": "P21677-1", "name": "Transcription factor E2-alpha", "aln": "MMNQSQRMAPVGSDKELSDLLDFSMMFPLPVANGKGRPASLAGTQFAGSGLEDRPSSESWGNSEQNSSSFDPSRAYSEGAHFSDSHSSLPPSTFLGAGLGGKGSERNAYATFGRDTSVGTLSQAGFLPGELGLSSPGPLSPSGVKSSSQYYTSFPSNPRRRAADGGLDTQPKKVRKVPPGLPSSVYPSSSG----DNYSRDATAYPSAKTPSSAYPSPFYVADGSLHPSAELWSPPGQVGFGPMLGDGSAPLPLAPGSSSVSSG----AFGGLQQQDRMGYQLHGSEVNGTLPAVSSFSAAPG-TYSGTSGHTPPVSG--ADSLLGTRGTTASSSGDALGKALASIYSPDHSSNNFSPSPSTPVGSPQGLPGTSQWPRAGAPSALSPNYDAGLHGLS-KMEDRLDEAIHVLRSH--------------AVGTASELHGLLP------GHSTLTTSFAGPMSLGGRHAGLVSGSHPEDGLTSG--------ASLLHNHASLPSQPSSLPDLSQRPPDSFSGLGRAGVTAGASEIKREEKEDEEVTSVAD-AEEDKKDLKVPR--TRTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLSTEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSG---------VVGDPQ-------------------------------LALSAAHPGLG-------EAHNPAGHL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15806-1", "uniprot_id": "TFE2_MOUSE", "id": "P15806-1", "name": "Transcription factor E2-alpha", "aln": "MMNQSQRMAPVGSDKELSDLLDFSMMFPLPVANGKSRPASLGGTQFAGSGLEDRPSSGSWGSSDQNSSSFDPSRTYSEGAHFSDSHSSLPPSTFLGAGLGGKGSERNAYATFGRDTSVGTLSQAGFLPGELSLSSPGPLSPSGIKSSSQYYPSFPSNPRRRAADGGLDTQPKKVRKVPPGLPSSVYPPSSG----DSYSRDAAAYPSAKTPSSAYPSPFYVADGSLHPSAELWSTPSQVGFGPMLGDGSSPLPLAPGSSSVGSG----TFGGLQQQDRMGYQLHGSEVNGSLPAVSSFSAAPG-TYSGTSGHTPPVSGAAAESLLGTRGTTASSSGDALGKALASIYSPDHSSNNFSPSPSTPVGSPQGLPGTSQWPRAGAPSALSPNYDAGLHGLS-KMEDRLDEAIHVLRSH--------------AVGTASDLHGLLP------GHGALTTSFTGPMSLGGRHAGLVGGSHPEEGLTSG--------ASLLHNHASLPSQPSSLPDLSQRPPDSYSGLGRAGTTAGASEIKREEKEDEEIASVAD-AEEDKKDLKVPR--TRTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLSSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSG---------VVGDPQ-------------------------------LALSAAHPGLG-------EAHNPAGHL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15923-1", "uniprot_id": "TFE2_HUMAN", "id": "P15923-1", "name": "Transcription factor E2-alpha", "aln": "-MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSG----EDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSG--ADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSH--------------AVGTAGDMHTLLP------GHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGS--------TSLMHNHAALPSQPGTLPDLS-RPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPR--ARTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRERNLNPKAACLKRREEEKVSG---------VVGDPQ-------------------------------MVLSAPHPGLS-------EAHNPAGHM----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11420-1", "uniprot_id": "DA_DROME", "id": "P11420-1", "name": "Protein daughterless", "aln": "---------MATSDDEPMHLYEVFQNCFNKIAN--KQPTGTVGADRGGGGGYHSPYGSLGVENGMYPSDFNSMHDTVNGGNNRYANASTVDQYFDSAAAGS-----------GGAWCQPQMSSANSYMGQSAYQNSGPLSGHSIDQQQQQVHQADGLGMGGGGGGGVGADGMHCPVTTGLPPISSFRPTSGGIGGPGAGQQAPVNVNVNPPAVFNSPQAHNHNHTVQAQHSALSTAGPLGHHSLNHTPHAHSHTLPLPHALPHG---HTLPHPHHSQQNSPAVQSSDAFSGAGASVKVAGAGN-SSAAALRQQMYMPADQSISSFGSNPSTPVNSPPPLTQSVVGGGGEPSVSGGSGWGHSVLNGGP-----SSSYASEMVPVSSLHTMASVFQGVR--MEERLDDALNVLRNHCEPEMLAGVNQSLASIDNIDALTSFVPNSPSHLGSGGNSGSVSNTSNAALVHEVLALGAAAAAGTSGQSVGGAGSLASLKLDRSASTSLPKQTKKRKEHTAISNSVPAGVSTTSSLTSLDISDTKPTSSIESSNSGLQQHSQGKGTKRPRRYCSSADEDDDAEPAVKAIREKERRQANNARERIRIRDINEALKELGRMCMTHLKSDKPQTKLGILNMAVEVIMTLEQQVRERNLNPKAACLKRREEEKAEDGPKLSAQHHMIPQPQQVGGTPGSSYHSQPAQLVPPSSQTISTMTISLPVNQANNGLPPHLQQQQQQQSQLGHAQLPQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*.* .* :. ::* :*:. *:: .*.* . * . .. .*.*:. : :* : :::* . * ... *. * ::.*. *: . ...**** .:. .* . . ...*.:.:: : .. * * : .:** . .::*.. ..:.*: .. : : :::.. . *... *. .: : * . .: . :: :: :: . ::.::. . : ..:.* . : ... : :.. : * :*:. :*. .* .* :::.. . *.. . . *. *.* :*.:. .* : . . ::*: :*::**:*::***.* ::.. . : ::* * . : ..:.. . . * *. *: . * :. :** :::: .* * . . :.. * * . ...*:. :.:. .:.: . . :: . :::.: * .: * ... **** * ** ****** *******:*:******:******* **.::****** **: ** **:.************************... :: :** : :. .: ** : :. ** ", "identical_positions": 147, "similar_positions": 246, "identity": "19.78%" }, { "cls_id": "homologset.agr.RGD:620915", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60296-1", "uniprot_id": "TRAK2_HUMAN", "id": "O60296-1", "name": "Trafficking kinesin-binding protein 2", "aln": "-------------------MSQSQNAIFTSPTGEENLMNSNHRDSES--ITDVCSNEDLPEVELVSLLEEQLPQYR---------LKVDTLFLYENQ---------DWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYG---------AFTGESLAAEIEG-TMRKKLSLDEESSLFKQKAQQ---------------------------------KRVFDTVRIAN------DTRGRSISFPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEEVAGSS------QKMGQPGPSGDSDLATALHRLS----LRRQNYLSEKQFFAEEWQRKIQVLAD--QKEGVSGCVTPTESLASLCTT--QSEITDLSSASCLRGFMPEKLQIVKPLEGSQTLYHWQQLAQPNLGTILDPRPGVITKGFTQLP--GDAIYHISDLEEDE----------EEGITFQVQQPLEVEEKLSTSKPVTGIFLPPITSAGGPVTVATA-----NPGKCLSCTNSTFTFTT----CRILHPSDITQVTPSSG-------FPSLSCGSSGSSSSNTAVNSPALSYRLS--------------------------------------------------------------------IGESITNRRDSTTTFSSTMSLAKLLQ--------ERGISAKVYHSPISENPLQPL-PKSLAIPSTPPNSPSHSPCPSPLPFEPRVHLSENFLASRPAETFLQEMYGLRPSRNPPDVGQLKMNLVDRLKRLGIARVVKNPGAQE----NGRCQEAEIGPQKPDSAVYLNSGSSLLGGLRRNQSLPVIMGSFAAPVCTSSPKMGVLKED---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R2H7-1", "uniprot_id": "TRAK2_RAT", "id": "Q8R2H7-1", "name": "Trafficking kinesin-binding protein 2", "aln": "-------------------MSLSQNAIFKSQTGEENLMSSNHRDSES--ITDVCSNEDLPEVELVNLLEEQLPQYK---------LRVDSLFLYENQ---------DWSQSSHQQQDASETLSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELSKKEELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLDMMHEKLKELEEENMALRSKACHIKTETFTYEEKEQKLINDCVNELRETNAQMSRMTEELSGKSDELLRYQEEISSLLSQIVDLQHKLKEHVIEKEELRLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRNKAGPSAHLCFSQAYG---------VFAGESLAAEIEG-TMRKKLSLDEES-VFKQKAQQ---------------------------------KRVFDTVKVAN------DTRGRSVTFPVLLPIPGSNRSSVIMTAKPFESGVQQTEDKTLPNQGSST-EVPGNS------HPRDPPGLPEDSDLATALHRLS----LRRQNYLSEKQFFAEEWERKLQILAE--QEEEVSSCEALTENLASFCTD--QSETTELGSAGCLRGFMPEKLQIVKPLEGSQTLHHWQQLAQPNLGTILDPRPGVITKGFTQMP--KDAVYHISDLEEDE----------EVGITFQVQQPLQLEQKPAPPPPVTGIFLPPMTSAGGPVSVATS-----NPGKCLSFTNSTFTFTT----CRILHPSDITQVTPSSG-------FPSLSCGSSAGSASNTAVNSPAASYRLS--------------------------------------------------------------------IGESITNRRDSTITFSSTRSLAKLLQ--------ERGISAKVYHSPASENPLLQLRPKALATPSTPPNSPSQSPCSSPVPFEPRVHVSENFLASRPAETFLQEMYGLRPSRAPPDVGQLKMNLVDRLKRLGIARVVKTPVPRE----NGKSREAEMGLQKPDSAVYLNSGGSLLGGLRRNQSLPVMMGSFGAPVCTTSPKMGILKED---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q960V3-1", "uniprot_id": "MILT_DROME", "id": "Q960V3-1", "name": "Trafficking kinesin-binding protein milt", "aln": "MTHVNNGEVMEKEMEPTGERERDRETAAGSGVHHRFLASASERDANSGNALEAAATKTKTGTTITNLEDLAFEACQNWSDLHQDFFITDDELEYEDELSLGSSIGGNIATTTTADAAVEGLITGEHQNEQLLMEVLCGNRVSQMTRAYDDIEAVTRLLEEKEKDLELTVQIGKELLTQNNALEARVADLETDLKASNDDRAQLVHELHKKNELISVLTNDADDGTDTDTPTMSKS-----------ITLDLLQRKVNSLLDENKSLKCEATQLAHQTDEVEEHERQLMADISAQLNDANSQYDNLSLELERQREENRLQHEQIVNLTARLAEAEMRLHQLTQDNDEHLSLLHVTKENQNALALELVEFKQRYEEVLALLHSAQDQLKQQRKRSQPQARSSFLGGLGTSGAGMGGSLFPPDSLHCELMESSLYSENSLDSGISGDSQRSADRISRMMMHMPSGGMSSSTMGGSVYAGAGNVPPYKRVFDTVRCAGKSGNYMDSGNVSMTQLGAMSMSSSSGPRMASMAYPAGSYYRGGSNQSLGVKTLSSESLNSQSDDGYPAQPSGVPGAPGAKELEAALKRLTPAEVLARRAMLSYAPAGTYNYDEPMGHGTGNVRNSDLPLGVRTPDSIMSTGSSGMSGSTNHMSASMTHQWRLPEKLQIIKPMEGSQTLHHWSRLATPTLSGLLDERPGVTIRGGRGLDDLGMQIYTLSDVEEDVSDDLPGKQFEAPGCTFTYTNSMVMHPDDGFVNDLSFLSQSQMSSRMASTSTSRQPSCPATPRAGLSRKNSCSTFSVNLGLAGMLNERGIKAVTPSALNTPAGPNFSPTVTPCNSPEGSPPRAQSPEPLFGLLSCGADLIRRKIVGDQHQQQQQKQRSSLSKQQQQKIMLSHLERRALRSLNLIEKVESIGLENIISAQRGLGSGIANRSSSPLSSGSLQSLHTSSNSIVDDIHFDRAQIKGVLHRGLKSPTPATASTSAAAAASGPGISTSSSTSAYNSDDSDDQGLVMKIKPSKSATPTTTGAAQSQPSSATTSNGTASETRLKQMQRQKSRRQLKNGMANQRPDLGTISGAGGGGRVRPDLGKVADSGSSSKLSTKRSEAKPAEE-EEATPQTITQAFVGSVSSLLFGRKGGWL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .::: * . .. * .:..**::* :..:.: . . :..* : : : : .* : **:: : : :. .. :: :* : :* :**.***::*:**: **:** *:::****:.:**: **.:*:.*. : .** :* : *: ** *** **:**: ::: :::. .: : . : *::::.*::.* :** :*:.:* :: :* **:*::*: * :*.::*:* ..:: **. : :* :*:: .* :::.: : :*:: . :::* *:.:*: *. *::** *:::* * *.:**.:*:::*: *.:: * *: * . * *. :** .*: :: .: ***. .*:: : *******: *. *: . *:: :.:..*. . : * * * : .:::* : *: .: ..* : . ** . .:* :**:**: * *: ** : :::. : : ::. :. .:.: * : ... ..:.:: : :******:**:******:**.:** *.*. :** **** :* : :* :**:*** * ** :.: :. . . :: : . ::* ...:.: .* ** .** **:. . :*: .*. ****: *.. ... ..* . .:** : * :*..*:** .*. : .* ** . : :*. * * .. . ..: * .* * *.* *... . : :: .*:.* . :** ... * . . :.:::* * :*. ..: . . . * :** . :**.* . :*.:: *. . .:* :.. :* :.. ", "identical_positions": 216, "similar_positions": 352, "identity": "19.05%" }, { "cls_id": "homologset.agr.RGD:620916", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K344-1", "uniprot_id": "PK3CA_RAT", "id": "A0A0G2K344-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "aln": "MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNGETATKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG-AQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42337-1", "uniprot_id": "PK3CA_MOUSE", "id": "P42337-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "aln": "MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFREARKYPLHQLLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG-AQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42336-1", "uniprot_id": "PK3CA_HUMAN", "id": "P42336-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "aln": "MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG-AQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QAD7-1", "uniprot_id": "F1QAD7_DANRE", "id": "F1QAD7-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "aln": "MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHHLLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGAHSRALYVYPPNVESSPELPKHIYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMDNFTMPSYSRRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRVARDHAMTEADIEQLRQLGNRDPLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSTTLHQWLKDKNKGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************:********:**********:*******:********:***:*:****************:************************************.*********:******************::*:*** ...****:******************.****************************************************:****:** ****************:*****:*****:********:******:*:*******:* ********************::*****.***:***::*************************** *********************.**:****:******************************:******.********************************************:*** ******:.**:**** :*** *:.*.::* *.*:***: : * * ***: : .**************** **:***.*******:**:***************:****.******************:*.********************************** ******************************************************.*************************************:**:*****.* ***************:************************************************************************************.********************* *************:** *************************************************************************** :** *****************************************************************:** **********************::** *", "identical_positions": 972, "similar_positions": 74, "identity": "90.93%" }, { "cls_id": "homologset.agr.RGD:620917", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1L0-1", "uniprot_id": "PK3CB_RAT", "id": "Q9Z1L0-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "aln": "MCFRSIMPPAMADTLDIWAVDSQIASDGSISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE-KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTYPPEHEPSVLENLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEEEASP-CDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINRNSSSLPLPLPPKK----------------TRVISHVWGNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYAENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASGDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALDNRRIGQFLFWHLRSEVHTPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLN--RAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCRYMDSKMKPLWLVYSNRAFGEDAVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTI9-1", "uniprot_id": "PK3CB_MOUSE", "id": "Q8BTI9-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "aln": "------MPPAMADNLDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE-KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEAKIQSLVGLSWIDWLKHTYPPEHEPSVLENLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEDEASP-CDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLPLPLPPKK----------------TRVISHIWDNNNPFQITLVKGNKLNTEETVKVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYAENATALHITFPENKKQPCYYPPFDKIIEKAAELASGDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALDNRRIGQFLFWHLRSEVHTPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLS--RAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYSSRAFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42338-1", "uniprot_id": "PK3CB_HUMAN", "id": "P42338-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "aln": "MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE-KLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEHEPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDEVSP-YDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLPLPLPPKK----------------TRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLN--RAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F251-1", "uniprot_id": "E7F251_DANRE", "id": "E7F251-1", "name": "phosphatidylinositol-4,5-bisphosphate 3-kinase", "aln": "------MPPAKTDQLDLWA-ESGLDGDDQVMVDFLLPTGIYIQMEVPRESTIQHIKLLLWKEAQTYPLFSLLGEMEGHMFECVNQAAVHEELEDETRRLCDVRPFLPVLKLITRNCGRAERLLDSKIGVLIGKGLHELDALQDQEVKDFRSKMKRISEEKMQQMQMMSWGQWLRSSYSPQLDTSSLDNLIERHEG-IIKITMHYDQSQDTASLKVSLNCTVSEVMDHALKKWQTTHGPEEDIGARSNYVLRVSDRLEFLFEDYPLIQYKYIRACLSTGENPHLTVVHFDIVKSMFEKEIATVGSVLARKTSNPPLPLPPKKRQTTVRTSSMSASQLPQQLHTCVWKVHSLFRINLVKANKVNAEDAAKIQVRAGLFHGTELLCKTAVSNESSSRSEHVWNKTLEFDIPVCDLPRMARLCFAIYAVMDKVKKQRSTKNTHLNKYQTIRKAGKVHYPIAWVNTMVFDYRGQLKTGDIILHCWSSFPDELEEMLNPIGTIQTNPYTENATELHISFPEYSTQPVVFPAFDKILEKAAEIAGASDSMSMGRGGKKFYIELKEIMERDPLSQLCENEKDLIWTLRYDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREFAVSCLKDMSDDELLQYLLQLVQVLRYEPYYDCSLSRFLLERAQTSRKIGHFLFWHLRSEMYMPAVSVHFALILEAYCRGCIPHIEVLKKQVEALNKLKAVNELIKLGTIKTKTKQAHLKEAMMSCLRQTGFIETLSDLHSPLNPNILLAGVSVEKCKYMDSKMKPLWIVYNNKLLGGETVGIIFKNGDDLRQDMLTLQILKLMDLLWKEANLDLRIVPYGCLATGDHSGLIEVVSSADTIANIQKTSSNMAAAAAFNKDALLNWLKDKNSGDALDKAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQEGKTGNTEKFGNFRQYCEEAYMILRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKTDEEALKQFRQKFDEALRESWTTKVNWMAHIVAHPS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** :* **:** :* : .*. : ************:*****:**.:** :***:.:.**:*.** :::.:** ****:**:**********************:**.*. .* ***************:*:*:* **::** **:::** *: .: :** :**: :*.*: :.* :** :: * : :::*:::.**. *::** * . :: : *::* * :* *:: .. :***:**.*:*::* *:****::*** *: . **: :*. :*.*:*:*: :: :.: *::*. ******** :: : :* :. *:* ***.**:*:*::.*::*************** **.* *.:.:*:**: ***** :************:***:****.::***. : .**************:*********::***::**:***.**************:**:*****:**** **:.*** ..** :*.****:*****:*....: .****** ****::*********** ******* **** ***********:**.* **:*************.**:****************:**.**::***:** **********:***: **:********* .*:**:*********:: ****::*.:********.: *::**.**********::*.****.::* . :*: **** :**:*:.: *:****:***** ::*: : ****:**********:**..: :* ::**:****************:*:*********.****::*********:********:::***:** .***:**:*************: **** **:***************:***************:.********************************:*******:**********.*** **:**:***::************************************::*******:******************** * : ", "identical_positions": 714, "similar_positions": 242, "identity": "65.5%" }, { "cls_id": "homologset.agr.RGD:620918", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23640-1", "uniprot_id": "RB27A_RAT", "id": "P23640-1", "name": "Ras-related protein Rab-27A", "aln": "MSDGDYD--------YLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRANGPDGTVGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRAVKEEEARELAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRMERCVDKSWIPEGVVRS-------NGHTS-----TDQLSEEKEKGLCG-C", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERI2-1", "uniprot_id": "RB27A_MOUSE", "id": "Q9ERI2-1", "name": "Ras-related protein Rab-27A", "aln": "MSDGDYD--------YLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRANGPDGAVGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRAVKEEEARELAEKYGIPYFETSAANGTNISHAIEMLLDLIMKRMERCVDKSWIPEGVVRS-------NGHTS-----ADQLSEEKEKGLCG-C", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51159-1", "uniprot_id": "RB27A_HUMAN", "id": "P51159-1", "name": "Ras-related protein Rab-27A", "aln": "MSDGDYD--------YLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRMERCVDKSWIPEGVVRS-------NGHAS-----TDQLSEEKEKGACG-C", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O76901-1", "uniprot_id": "O76901_DROME", "id": "O76901-1", "name": "", "aln": "MRAAPPEPEPLQLAGSGEQFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNSRG------RRHRIHLQIWDTAGQERFRSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQLRVVSRDQVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIENAACNREFSLLLTQSRCLPNIAYGQPEDLVRLHDRREEPCSRRNCRNC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : :**.*********.:*******:*:::**:**********::*.: * * :*****:****************:********:****.*:***:. **:***: ***.*:**:******.** : *.*..::. *..:* :**:****..*:*:..*:*:*:. :*:*:*... : :. :.:* *:.. *: .* .: * *", "identical_positions": 115, "similar_positions": 70, "identity": "47.52%" }, { "cls_id": "homologset.agr.RGD:620919", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P1F6-1", "uniprot_id": "2ABA_MOUSE", "id": "Q6P1F6-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "aln": "--------------------------------------------------MAGAGGG---NDIQWCFSQVKG-AVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEE----------------DGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFD------------------------------RNTKRDITLEASRENNKPRT------------------------------------VLKPRKVCASGKRK--------KDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63151-1", "uniprot_id": "2ABA_HUMAN", "id": "P63151-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "aln": "--------------------------------------------------MAGAGGG---NDIQWCFSQVKG-AVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEE----------------DGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFD------------------------------RNTKRDITLEASRENNKPRT------------------------------------VLKPRKVCASGKRK--------KDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36876-1", "uniprot_id": "2ABA_RAT", "id": "P36876-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "aln": "--------------------------------------------------MAGAGGG---NDIQWCFSQVKG-AVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEE----------------DGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFD------------------------------RNTKRDITLEASRENNKPRT------------------------------------VLKPRKVCASGKRK--------KDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2BG80-1", "uniprot_id": "A2BG80_DANRE", "id": "A2BG80-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B", "aln": "--------------------------------------------------MAGAGGGG--NDVQWCFSQVKG-AIDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQETENKSQPQCRSEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEE----------------DGRYRDASTITTLRVPVFRPMDLMVEASPRRVFANAHTYHINSISVNSDNETYLSADDLRINLWHLEITDRSFNIVDIKPANMEDLTEVITAAEFHPHQCNTFVYSSSKGTIRLCDMRASALCDKHSKLFEEPEDPSNRSFFSEIISSISDVKFSHNGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGNDSVVMTGSYNNFFRMLD------------------------------RTQRRDVTLEASRESCKPRQ------------------------------------VLKPRRVCAGGKRK--------KDEISVDSLDFNKKILHTAWHPQENIIAVATTNNLYIFQEKVN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36872-1", "uniprot_id": "2ABA_DROME", "id": "P36872-1", "name": "Protein phosphatase PP2A 55 kDa regulatory subunit", "aln": "MGRWGRQSPVLEPPDPQMQTTPPPPTLPPRTFMRQSSITKIGNMLNTAININGAKKPASNGEASWCFSQIKG-ALDDDVTDADIISCVEFNHDGELLATGDKGGRVVIFQRDPASKAANPRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLQQKNPVHFLLSTNDKTVKLWKVSERDKSFGGYNTKEE----------------NGLIRDPQNVTALRVPSVKQIPLLVEASPRRTFANAHTYHINSISVNSDQETFLSADDLRINLWHLEVVNQSYNIVDIKPTNMEELTEVITAAEFHPTECNVFVYSSSKGTIRLCDMRSAALCDRHSKQFEEPENPTNRSFFSEIISSISDVKLSNSGRYMISRDYLSIKVWDLHMETKPIETYPVHEYLRAKLCSLYENDCIFDKFECCWNGKDSSIMTGSYNNFFRVFD------------------------------RNSKKDVTLEASRDIIKPKT------------------------------------VLKPRKVCTGGKRK--------KDEISVDCLDFNKKILHTAWHPEENIIAVAATNNLFIFQDKF-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00362-1", "uniprot_id": "2ABA_YEAST", "id": "Q00362-1", "name": "Protein phosphatase PP2A regulatory subunit B", "aln": "--------------------------------------------------MA-------QNNFDFKFSQCFGDKADIVVTEADLITAVEFDYTGNYLATGDKGGRVVLFER------SNSRHCEYKFLTEFQSHDAEFDYLKSLEIEEKINEIKWLRPTQRSHFLLSTNDKTIKLWKVYEKNIKLVSQNNLTEGVTFAKKGKPDNHNSRGGSVRAVLSLQSLKLPQLSQHDKIIAATPKRIYSNAHTYHINSISLNSDQETFLSADDLRINLWNLDIPDQSFNIVDIKPTNMEELTEVITSAEFHPQECNLFMYSSSKGTIKLCDMRQNSLCDNKTKTFEEYLDPINHNFFTEITSSISDIKFSPNGRYIASRDYLTVKIWDVNMDNKPLKTINIHEQLKERLSDTYENDAIFDKFEVNFSGDSSSVMTGSYNNNFMIYPNVVTSGDNDNGIVKTFDEHNAPNSNSNKNIHNSIQNKDSSSSGNSHKRRSNGRNTGMVGSSNSSRSSIAGGEGANSEDSGTEMNEIVLQADKTAFRNKRYGSLAQRSARNKDWGDDIDFKKNILHFSWHPRENSIAVAATNNLFIFSAL--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: .: *** * * *::**:*: ***:: *: ***********:*:: : **:. : ****:.***************:*:** .: :*********:****: *:: . * * .* * .: :*::* . :: *:*:* ::***********:*** **:***********:*:: ::*:*******:***:******:***** .** *:********:***** :***.::* *** :* *:.**:** *****:*:* .***: :****::*:**::*:.:*::* :** *: :*.. ****.****** :.*..* :******* * : :. :: .:* : * : **:. :.. .** ::: * :**:*:*** :***.** ****:****:**. ", "identical_positions": 223, "similar_positions": 118, "identity": "37.73%" }, { "cls_id": "homologset.agr.RGD:620920", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BG02-1", "uniprot_id": "2ABG_MOUSE", "id": "Q8BG02-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform", "aln": "---------------------------------------------------------MGEDTDTRKINHSFLR-DHSYVTEADVISTVEFNHTGELLATGDKGGRVVIFQREPESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITER----------------DKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRTFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYESDCIFDKFECAWNGSDSVIMTGAYNNFFRMFD------------------------------------------------RNTKRDVTLEASRESSKP------------------RAVLKPRRVCVGGKRR--------RDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97888-1", "uniprot_id": "2ABG_RAT", "id": "P97888-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform", "aln": "---------------------------------------------------------MGEDTDTRKINHSFLR-DHSYVTEADVISTVEFNHTGELLATGDKGGRVVIFQREPESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITER----------------DKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYESDCIFDKFECAWNGSDSVIMTGAYNNFFRMFD------------------------------------------------RNTKRDVTLEASRESSKP------------------RAVLKPRRVCVGGKRR--------RDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2T4-1", "uniprot_id": "2ABG_HUMAN", "id": "Q9Y2T4-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform", "aln": "---------------------------------------------------------MGEDTDTRKINHSFLR-DHSYVTEADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITER----------------DKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFD------------------------------------------------RNTKRDVTLEASRESSKP------------------RAVLKPRRVCVGGKRR--------RDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5I6-1", "uniprot_id": "A0ACD6B5I6_DANRE", "id": "A0ACD6B5I6-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B", "aln": "-------------------------------------------------------------MLSPVLCSDLAA-LEPEYTDADVISTVEFNQTGEFLATGDKGGRVVIFQREP--------LGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPPHNPAHFLLTTNDKTVKLWKVSER----------------DKRAEGYNLRDEEGRLKDLSTITTLQVPVLRPMDLLVEASPRRVFANAHAYHINSISVNSDCETYLSADDLRINLWHLSITDRSFNIVDLKPENMEDMSEVITVAEFHPHHCHLLAFSSSTGTTRLCDMRARALCDQHAKLFEEAVDPTRRSFFSEIVSSVSDVKFSHSGRYLLTRDYLTVKVWDLNMENKPVEVYQVHDYLRTKLCSLYESDCIFDKFECAWNGTDSVIMTGAYNNYFRMFD------------------------------------------------RASRRDVTLEASREVCKR------------------RAVLQPRRVCVGKKRK--------ETDVSVDSLDFRKKILHTAWHPKENIIAIAASNNLYIFQDRLTPNGHHNTPEIQSAPPK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36872-1", "uniprot_id": "2ABA_DROME", "id": "P36872-1", "name": "Protein phosphatase PP2A 55 kDa regulatory subunit", "aln": "MGRWGRQSPVLEPPDPQMQTTPPPPTLPPRTFMRQSSITKIGNMLNTAININGAKKPASNGEASWCFSQIKGA-LDDDVTDADIISCVEFNHDGELLATGDKGGRVVIFQRDPASKAANPRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLQQKNPVHFLLSTNDKTVKLWKVSER----------------DKSFGGYNTKEENGLIRDPQNVTALRVPSVKQIPLLVEASPRRTFANAHTYHINSISVNSDQETFLSADDLRINLWHLEVVNQSYNIVDIKPTNMEELTEVITAAEFHPTECNVFVYSSSKGTIRLCDMRSAALCDRHSKQFEEPENPTNRSFFSEIISSISDVKLSNSGRYMISRDYLSIKVWDLHMETKPIETYPVHEYLRAKLCSLYENDCIFDKFECCWNGKDSSIMTGSYNNFFRVFD------------------------------------------------RNSKKDVTLEASRDIIKP------------------KTVLKPRKVCTGGKRK--------KDEISVDCLDFNKKILHTAWHPEENIIAVAATNNLFIFQDKF-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00362-1", "uniprot_id": "2ABA_YEAST", "id": "Q00362-1", "name": "Protein phosphatase PP2A regulatory subunit B", "aln": "---------------------------------------------------------MAQNNFDFKFSQCFGDKADIVVTEADLITAVEFDYTGNYLATGDKGGRVVLFERSNS------RHCEYKFLTEFQSHDAEFDYLKSLEIEEKINEIKWLRPTQRSHFLLSTNDKTIKLWKVYEKNIKLVSQNNLTEGVTFAKKGKPDNHNSRGGSVRAVLSLQSLKLPQLSQHDKIIAATPKRIYSNAHTYHINSISLNSDQETFLSADDLRINLWNLDIPDQSFNIVDIKPTNMEELTEVITSAEFHPQECNLFMYSSSKGTIKLCDMRQNSLCDNKTKTFEEYLDPINHNFFTEITSSISDIKFSPNGRYIASRDYLTVKIWDVNMDNKPLKTINIHEQLKERLSDTYENDAIFDKFEVNFSGDSSSVMTGSYNNNFMIYPNVVTSGDNDNGIVKTFDEHNAPNSNSNKNIHNSIQNKDSSSSGNSHKRRSNGRNTGMVGSSNSSRSSIAGGEGANSEDSGTEMNEIVLQADKTAFRNKRYGSLAQRSARNKDWGDDIDFKKNILHFSWHPRENSIAVAATNNLFIFSAL------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *:**:*: ***: *: ***********:*:*. **.. : ****:.***************:*:** : * **:*****:****: *: * * ... * :: .: :*::* : :: .:*:* ::*.*:*******:*** **::**********:* : ::*:****:** ***:::**** :**** .*::: :***.*: :***** :***.::* *** :* .:.**:** **:**:*:* .***: :****::*:**::*: :*::. :*: *: :*.. **.*.****** :.* .* :***:*** * :: * . ::. : .* : : . **:. :.. ** . . * :** *:*** :*** ** **:**:***:**. ", "identical_positions": 196, "similar_positions": 126, "identity": "32.29%" }, { "cls_id": "homologset.agr.RGD:620921", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W240-1", "uniprot_id": "Q9W240_DROME", "id": "Q9W240-1", "name": "K Homology domain-containing protein", "aln": "------------------------------------------METPSELTEKQNQDQ-----PTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKE-PFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEM--------NPKSAKKSNGLN---------------------MAPYRSNFDKAIGA-------------------IRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCS---------------------PVVRL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W224-1", "uniprot_id": "Q9W224_DROME", "id": "Q9W224-1", "name": "", "aln": "------------------------------------------METQSEFTEEQNQDQPTQDQPTYQPRLNEVAQKFLADLDEERKRLSAEFPLCALLIDESVDRVFSTGRIPGKE-FYADVYHQRPMKITQKVFVPVNKFPKFNFARKILGPKGNSVRRLKEETNCKIVIKGRSSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEM--------NPESAKKSNGLN---------------------MAPYRSIFDKTIGG-------------------NRNGAPKYNNQIRRVTENPREVADMEEVEYDYDEHRMPPSRPSLGFEYSKPPPSMTATNATPFKRAYP--YPTDMNR----------------TREPPIKSYKPNPYTILNKYINN-----------------------------------------RAPSDFVAQRYN----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2D0-1", "uniprot_id": "Q9W2D0_DROME", "id": "Q9W2D0-1", "name": "K Homology domain-containing protein", "aln": "---------------------------------------MEKMENPSEITEEQPTTT-----HEYQPRLNEIAQKFLADLDEERQRLSAEFPLCALLIDEARDRVYATGRIPGKE-LYADVYRQKPMKIIQKVFVPVNQYPKFNFAGKILGPKGNSLRRLQEETQCKIALKGRSSMRDRNKEEELRS--DPRYAHLQKNLFLEVSTVAIPAECHSRIAYALAEIRKYLIPDNNDEVSHEQLRELMEI--------DPESAKNFKGLN---------------------LEAYRSVRD-------------------------SNGASKYINLIKRVAENPSKVADMEQVDYDYDEHHMPPIHLPTGYEYSIQRPS---KIVAKFKRPYP--YPTDMKP----------------VREPPIKFYKPNPG--IGTYVMK-----------------------------------------SMLG---AQ-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W254-1", "uniprot_id": "Q9W254_DROME", "id": "Q9W254-1", "name": "", "aln": "MAENGLRVPGSSAVASAVASTATGVGGGSAAGTAGAGTGVVPTGVSGGTSNGEHENEHNANADGEKAQPAPAVQKYMQELMTERSRMENHFPLAVKLIDEALERVQLNGRIPTRD-QYADVYQQRTIKLSQKVHVPIKDK-KFNYVGKLLGPKGNSLRRLQEETQCKIVILGRFSMKDRAREEELRNSADAKYAHLNLPLHVEVSTIAPPAEAYARVAYALAEIRRYLTPDKHDDIRQEQYRELME---------DPEAAKKLTLRQ---------------------LQQQSNAAASGAGGGGGGGGGNGNGGAAGSGSNNGNGNQRSGGNYRQKFQQQSHYRHNEETVYFRSHNNAYHQPKPYVPAAQRGNAMHTTLPPQAIVRASPPGMVVSAAS----------------FNGRNAGLGNAGGGGIMANSIVA-----------------------------------------TTGGGIGGAVPPNMRYRPAAPYQFVKK-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W255-1", "uniprot_id": "Q9W255_DROME", "id": "Q9W255-1", "name": "", "aln": "--------MPRDYDRD-----YNEDAADYKRKRRDE--EPAATGAPETPEADGGGHTTSHAALRDTPQLNEKTNAYLQECLLEKKTLEKKHIITKRLLDDEVEKILVSGRIPKPE-IYANVYSEKPIRVAQKVLFPIKEYPKFNFVGKILGPKGNTLRQLQEETMCKMVVMGRNSMRDHGKEEELRSSGNPKYAHLSRDLHVEISTVAPPAEAYHRISYALGEIRKFMIPDANDDIRLEQLREMDG---------KERMYKKSHHYS-----------KSYG-----DHGAYSSRTPPPASS------KPKVYSILEKARYVMDDPN-YGIVKTHRSRDHELYD--HHGEYDRYATPPPQ--------TSKHSTHHAQYDSSSYERDY-RREYHPHS-----------------SSSSYAAAYPAKPSNGRSSSSYR-----PTTSGSG--------------------------SHSSAHYETGSRSRESVRYRSAPYPKIR---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KFT9-1", "uniprot_id": "A0A0B4KFT9_DROME", "id": "A0A0B4KFT9-1", "name": "", "aln": "--------MTEKYDGNGDFSAFNDDDNDFGGKPRKPGGSIGAPGGAHNGDASAHDHGHHGGDPGGNVQINEKANEYIRDCMAERNRMDRKFPIAEKLLEGEIEKVQTTGRIPSREQKYADIYREKPLRISQRVLVPIREHPKFNFVGKLLGPKGNSLRRLQEETLCKMTVLGRNSMRDRVKEEELRSSKDPKYAHLNSDLHVEISTIAPPAEAYARIAYAMAELRKYLIPDSNDIIRQEQLRELMDSTSLNDNDNAKSGYKKTSHMQGGNNVLGGGSINPIGGVKNTPHHSYRSSQPSSFSKNVLAP-KQKVMSILEKARTAMDETYGRGYDDGLGYDPHQSYDSYSYGTHGHGPHGPPANILGGVGGISGGGGRGGHYESSDYEPDYGRREYYQHSPGYSAGGGGGVGLGTGGASQSNAIGGSGLSSNHNRSHVNRXNLLDPSSASGGRGTNPAATTQNLTMKSQPNSSNNFLPNHGASECQNGKNINPNYYYNSNGSSKVNQQQLQQSQPNLPPQLSGHNNNSSNGSRASNMINTSSHNNCNSNFHPVGEKNSNDVSFISSYRLGPMDGQKSANSNNINNHTLGSKNHSNNTTTTASVPNMLLVRPANPSLHIGTFPFLPVQFF------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9JLP1-1", "uniprot_id": "KHDR3_RAT", "id": "Q9JLP1-1", "name": "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "aln": "-----------------------------------------------------------------------MEEKYLPELMAEKDSLDPSFTHALRLVNREIEKFQKGEAKDEEK--YIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEDIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKSTLRT---------------------RGVTTPAITRGRGG-------VTARPVAVGVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYSTAYDDQSYDSYDNSYSTPAQS-----------------GADYYDYGHGLGEEAYDSYGQE--------------------------------------DWTNSRHKAPSARTAKGVYREQPYGRY----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R226-1", "uniprot_id": "KHDR3_MOUSE", "id": "Q9R226-1", "name": "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "aln": "-----------------------------------------------------------------------MEEKYLPELMAEKDSLDPSFTHALRLVNREIEKFQKGEGKEEEK--YIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKSTLRT---------------------RGVTTPAITRGRGG-------VTARPVAVGVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQS-----------------AADYYDYGHGLSEDAYDSYGQE--------------------------------------EWTNSRHKAPSARTAKGVYRDQPYGRY----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75525-1", "uniprot_id": "KHDR3_HUMAN", "id": "O75525-1", "name": "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "aln": "-----------------------------------------------------------------------MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEK--YIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRT---------------------RGVPAPAITRGRGG-------VTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQS-----------------GADYYDYGHGLSEETYDSYGQE--------------------------------------EWTNSRHKAPSARTAKGVYRDQPYGRY----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W249-1", "uniprot_id": "Q9W249_DROME", "id": "Q9W249-1", "name": "K Homology domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------METKAGLSALEERSLKGSEKLKMLDITRDKPVKVAVKVAVPVRDHPKFNFVGKLLGPKGNSMKRLQEDTMCKMAVLGRGSMRDRRKEEELRGSGDSRYAHLFEDLHVEISTFAAPAEAHARIAYALAEVRRFLVPDYHDDIRQEQMWEMQALTSTPALGAHSLEDSHSPTINS-----------------SSQVGGTTNSSSNGASGRGLGGGLADMDTSNDDKSDDASGMECLSAVDKLDCSSSCASLGISGITTISTTSPEHPHPHQHHQQHQQHQQHHAHLHPAHAHGNQQQQQQVQHHHSHQAHFHQLLQQAHGGASAAAAACGEHLSGQTTPATAAALHT----------------------------TAMAVALQHQLTAAGIGGLLKPATGVGATMAGLPTTQAGAAALQLPGDGESSGSTLTLLEPPGTALLHPALRNVKTINIGGGLGRKRPLLGVPRSGMNPTKRTVMSLLARAKNSQALHSVRQPMVTATSFAEPLQMLASPFIIPHRAVDQPILALSKESLAQGV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . :: :: ::: :* .*:.. ***:. *:***:**::::*:*:* *: : *: **:*: :***** :.:* ** *.: :...* ***.: *:.:*: :::::: ** :* : * *: : ", "identical_positions": 39, "similar_positions": 57, "identity": "6.17%" }, { "cls_id": "homologset.agr.RGD:620922", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZT8-1", "uniprot_id": "RAB3B_MOUSE", "id": "Q9CZT8-1", "name": "Ras-related protein Rab-3B", "aln": "MASVTDGKTGIKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGRLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSMDTDPSVLGAS-KTTRLSDTPP-LLQQNCSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63941-1", "uniprot_id": "RAB3B_RAT", "id": "Q63941-1", "name": "Ras-related protein Rab-3B", "aln": "MASVTDGNTGIRDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVIPTEKGRLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSMDTDPSVLGAS-KTTRLSDTPP-LLQQNCSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20337-1", "uniprot_id": "RAB3B_HUMAN", "id": "P20337-1", "name": "Ras-related protein Rab-3B", "aln": "MASVTDGKTGVKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGQLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSLDTDPSMLGSS-KNTRLSDTPP-LLQQNCSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L986-1", "uniprot_id": "Q1L986_DANRE", "id": "Q1L986-1", "name": "small monomeric GTPase", "aln": "-MAKADQRFGQRDGSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFSSSFVSTVGIDFKVKTVYRNDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESYNAVQDWATQIKTYSWDNAQVILVGNKCDMDEERVVPFEKGKHLADQLGFEYYEASAKENINVRQVFERLVDIICVKMSERVDVEPPMVTGA-KTTRLTDKPP-QLPQNCC-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25228-1", "uniprot_id": "RAB3_DROME", "id": "P25228-1", "name": "Ras-related protein Rab-3", "aln": "MASGGDPK-WQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTLVGGGQKGQRLTDQPQGTPNANCNC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07560-1", "uniprot_id": "SEC4_YEAST", "id": "P07560-1", "name": "Ras-related protein SEC4", "aln": "--MSGLRTVSASSGNGKSYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDMET-RVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSNKLVG--VGNGKEGNISINSGSGNSSKSNCC-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .:.:* ::*:*:**:*.***:.:*.*:.:*.*..:*::*:*****:*** : *:****:********:*************:**:**:*:* ::. :::* . :: :: *:**::*****.**: **:. ::*. **.:**. : *:***:: .*. * *.. * *:.. . : . :.. . ** ", "identical_positions": 84, "similar_positions": 77, "identity": "38.01%" }, { "cls_id": "homologset.agr.RGD:620923", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62823-1", "uniprot_id": "RAB3C_MOUSE", "id": "P62823-1", "name": "Ras-related protein Rab-3C", "aln": "MRHEAPMQMASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQS-TRLKETPP-PPQPNCGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62824-1", "uniprot_id": "RAB3C_RAT", "id": "P62824-1", "name": "Ras-related protein Rab-3C", "aln": "MRHEAPMQMASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQS-TRLKETPP-PPQPNCGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96E17-1", "uniprot_id": "RAB3C_HUMAN", "id": "Q96E17-1", "name": "Ras-related protein Rab-3C", "aln": "MRHEAPMQMASAQDARYGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVISTERGQHLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQN-TRLKETPP-PPQPNCAC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25228-1", "uniprot_id": "RAB3_DROME", "id": "P25228-1", "name": "Ras-related protein Rab-3", "aln": "--------MASGGDPKW-QKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTLVGGGQKGQRLTDQPQGTPNANCNC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07560-1", "uniprot_id": "SEC4_YEAST", "id": "P07560-1", "name": "Ras-related protein SEC4", "aln": "--------MSGLR--TVSASSGNGKSYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDMET-RVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSNKLVG--VGNGKEGNISINSGSGNSSKSNCC-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. ... .:.:* ::*:*:**:*.***:.:*.*:.:*.*..:*::*:*****:*** : *::***:********:*************:**:**:*:* :*. :::* . :: :: *:**::*.***.*** **:: ::*. *..:**. *:*:***:: **: * *..:* :*:... .. : . : :.. . ..:.** ", "identical_positions": 86, "similar_positions": 89, "identity": "37.55%" }, { "cls_id": "homologset.agr.RGD:620924", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35276-1", "uniprot_id": "RAB3D_MOUSE", "id": "P35276-1", "name": "Ras-related protein Rab-3D", "aln": "MASASEPPASPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFTAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDIICDKMNESLEPSSSPGSNG-KGPALGDTPPPQPSS-CSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63942-1", "uniprot_id": "RAB3D_RAT", "id": "Q63942-1", "name": "GTP-binding protein Rab-3D", "aln": "MASASEPPASPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFTAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVSAEDGQRLAGDLGFEFFEASAKENINVKQVFERLVDIICDKMNESLEPSSSPGSNG-KGPALGDTPPPQPSS-CGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95716-1", "uniprot_id": "RAB3D_HUMAN", "id": "O95716-1", "name": "Ras-related protein Rab-3D", "aln": "MASAGDTQAGPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDVICEKMNESLEPSSSSGSNG-KGPAVGDAPAPQPSS-CSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25228-1", "uniprot_id": "RAB3_DROME", "id": "P25228-1", "name": "Ras-related protein Rab-3", "aln": "MASGGDP-KWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTLVGGGQKGQRLTDQPQGTPNANCNC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07560-1", "uniprot_id": "SEC4_YEAST", "id": "P07560-1", "name": "Ras-related protein SEC4", "aln": "MS--GLRTVSASSGNGKSYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDMET-RVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSNKLVG---VGNGKEGNISINSGSGNSSKSNCC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . .. .:.:* ::*:*:**:*.***:.:*.*:.:*.*..:*::*:*****:*** :.*::***:********:*************::*:**:::: :* :::* . :: :: *:**::*****.*:* **:. : *. ** :**. *:*:***:: **: :* *..:* :*:... . ..* :* : .. *", "identical_positions": 85, "similar_positions": 83, "identity": "38.46%" }, { "cls_id": "homologset.agr.RGD:620925", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYK2-1", "uniprot_id": "PRGC1_RAT", "id": "Q9QYK2-1", "name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "aln": "---------------MAWDMCSQDS--VWSDIECAALVGEDQPLCPDLPELDLSELDVNDLDTDSFLGGLKWCSDQSEIISNQYNNEP-ANIFEKIDE-------ENEANLLAVLTETLDSLPVD-------EDGLPSFDALTDGDVTTDNEASPSSMPDGTPPPQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHAN-HTHRIRTNPAIVK------------TENSWSNKAKSICQQQKPQRR--------PCSELLKYLTTNDDPPHTKPTENR----------------------------------------------NSSRDKCASKKKSHTQPQSQHAQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKPTTLSLPLTPESPNDPKGSPFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNPFKASPKLKPSCKTVVPPPTKRARYSE--CSGTQGSHSTKKGPEQSELYAQLSKSS-----------VLSRGHEERKTKRPSLRLFGDHDYCQSVNSKTD--ILINISQELQDSRQLDFKDASCDWQGHICSSTDSSQ-------------------------CYLRETLEASKQVSPCST----RKQLQD---QEIRAELNKHFGHPSQAVFDDKVDK---TSELRDGNFSNEQFSKLP-VFINSGLAMDGLFDDSEDENDKLSYP-----WDGTQSYSLFDVSPSCS-SFNSPCRDSVSPPKSLFSQRPQ-------RMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSCYYYESSHYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEANEHERLKRDEYRREYEKRESERAKQRERQ--------------------KQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYRYTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLD------SNSDDFDPASTKSKYDSLDFDSLLKEAQRSLRR--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70343-1", "uniprot_id": "PRGC1_MOUSE", "id": "O70343-1", "name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "aln": "---------------MAWDMCSQDS--VWSDIECAALVGEDQPLCPDLPELDLSELDVNDLDTDSFLGGLKWCSDQSEIISNQYNNEP-ANIFEKIDE-------ENEANLLAVLTETLDSLPVD-------EDGLPSFDALTDGAVTTDNEASPSSMPDGTPPPQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHAANHTHRIRTNPAIVK------------TENSWSNKAKSICQQQKPQRR--------PCSELLKYLTTNDDPPHTKPTENR----------------------------------------------NSSRDKCASKKKSHTQPQSQHAQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKPTTLSLPLTPESPNDPKGSPFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNPFKASPKLKPSCKTVVPPPTKRARYSE--CSGTQGSHSTKKGPEQSELYAQLSKSS-----------GLSRGHEERKTKRPSLRLFGDHDYCQSLNSKTD--ILINISQELQDSRQLDFKDASCDWQGHICSSTDSGQ-------------------------CYLRETLEASKQVSPCST----RKQLQD---QEIRAELNKHFGHPCQAVFDDKSDK---TSELRDGDFSNEQFSKLP-VFINSGLAMDGLFDDSEDESDKLSYP-----WDGTQPYSLFDVSPSCS-SFNSPCRDSVSPPKSLFSQRPQ-------RMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSCYYYESSHYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEAYEHERLKRDEYRKEHEKRESERAKQRERQ--------------------KQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYRYTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLD------TNSDDFDPASTKSKYDSLDFDSLLKEAQRSLRR--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBK2-1", "uniprot_id": "PRGC1_HUMAN", "id": "Q9UBK2-1", "name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "aln": "---------------MAWDMCNQDSESVWSDIECAALVGEDQPLCPDLPELDLSELDVNDLDTDSFLGGLKWCSDQSEIISNQYNNEP-SNIFEKIDE-------ENEANLLAVLTETLDSLPVD-------EDGLPSFDALTDGDVTTDNEASPSSMPDGTPPPQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHAN-HNHRIRTNPAIVK------------TENSWSNKAKSICQQQKPQRR--------PCSELLKYLTTNDDPPHTKPTENR----------------------------------------------NSSRDKCTSKKKSHTQSQSQHLQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKPTTLSLPLTPESPNDPKGSPFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRASPKLKSSCKTVVPPPSKKPRYSE--SSGTQGNNSTKKGPEQSELYAQLSKSS-----------VLTGGHEERKTKRPSLRLFGDHDYCQSINSKTE--ILINISQELQDSRQLENKDVSSDWQGQICSSTDSDQ-------------------------CYLRETLEASKQVSPCST----RKQLQD---QEIRAELNKHFGHPSQAVFDDEADK---TGELRDSDFSNEQFSKLP-MFINSGLAMDGLFDDSEDESDKLSYP-----WDGTQSYSLFNVSPSCS-SFNSPCRDSVSPPKSLFSQRPQ-------RMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSCYYYESSHYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEEYQHERLKREEYRREYEKRESERAKQRERQ--------------------RQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYRYTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLD------SNSDDFDPASTKSKYDSLDFDSLLKEAQRSLRR--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G1P7-1", "uniprot_id": "A0AC58G1P7_DANRE", "id": "A0AC58G1P7-1", "name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "aln": "---------------MAWDRCNQDS--VWRELECAALVGEDQPLCPDLPELDLSELDVSDLDADSFLGGLKWYSDQSEIISSQYGNEA-SNLFEKIDE-------ENEANLLAVLTETLDSIPVD-------EDGLPSFEALADGDVTNASDQSCPSTPDGSPRTPEPEEPSLLKKLLLAPANSQLSYNQYPGGKAQNHAA-SNQRIRPAPAVAKVAAHRTSCIKGLTENPWNSKPRGACPN-RSMRR--------PCTELLKYLTSSDEAFQTKAGEAKSTWTGCGKDRGGACISS-----------CSSSSSPSSSSTSSFSSLSSCSSSTASKKKTSSASPSSQQQQLAVQAQRGESQAASTCSVAGEGAGKWRRCTQGEQSAPIALSHGGGCGHACSGEERRPPGLHPGADPSSLAAARFIRYMHSYSLPPRETGHAGSCGHCLEAGGVAEAGHANRHITVTIRKRRQELEHPMLSQLLTSRPRPARYRAHLHLPSVPQNKRQDLLDKTPRVQESPGRLKQASCEQPRITPSSYEQTFSMGDQSNLECSSELKLDLESWLSMPEQVTGSGLHDLVGHAGEDVFDDVIGSPMSFSQGLPSPLFPDSLVPERTPSDSQKQALCKHLDDQVPPMLAKPTILPLPLTPESPNDHKGSPFENKTIERTLSVEICGTPGLTPPTTPPHKASQENPFKVSLKNKLSSCSPSALTSKRPRLSNGGSCPQPTSGSIRKGPEQTELYAQLSKASST---------MPQGGLEDRRGKRPMPRVFGDHDYCQSTSTKRDSTTPAAVVPGPTEGRHVECKDLNMPTSTTTTSSLSSTPPSSSSLARQLQGLSPTPQEACPDTYAHVQHHDSSSKMTMDCSSG--GRKLLRD---QEIRDELNKHFGKPQQAFYSGVVGEPRGKQPIEDSDSGDEYPGLLG-DYIHPGLPD---FEDLEVGRERLFYL-----GEGSPLELLLEGSPSSSPSSSSFSWCSVSPPSSQLSPQHLRWPRSISRSRSRSSSHHRRRSLSRSPYSRSGS--PSSRSPSWSPRNMDESTFTPRICGNP----QSQSHSLFGRRPRYDSYEEYQHERLKREEYRRDYEKRECERAEQRERQ--------------------RQKAIEERRVVYVGRLRADSTRTELKRRFEVFGEIEESTVNLRHDGDNFGFITYRYTCDALAALENGHTLRRSNEPHFELCLGGQKQYSKSNYTDLD------SHSDDFDPASTKSKYDSMDFDSLLREAQYSLRR--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPM1-1", "uniprot_id": "Q8IPM1_DROME", "id": "Q8IPM1-1", "name": "", "aln": "MDSRMLNVFQGDTFEANYTKYESEP-IFWSSNDELQLTDTLSGILPIAPTDESLLNHNREEDLQNRKNLLIYNDFLKQELSNHDANELNAQVYRSIADSGGEIAYEQQRQISAIVEYDKEDIKIDGLTEEEDIQSQSTFRTRTDSSSIGDYESHSSDYDDEFDIVNEEKSP-RLQVVHNNIGNLQSSCERKGRTLSTNTIISEVDALGLSIDVNNFDLADFITKDDFAENLNACRKKESLQAQAQIKSNTLADVPILLNPPVATIVAKPGVPSSKPGDSDYDSDSIIDVETVDVLDMNMANIWSIDKPAKMGQTPDELRYVDNVKADPSWSPRSAKKTTPTIKENKPEQLGNHQLAVPASNKPKHKNICLVPNKKQCDFLKRKVGSPSLSKLTKATTKKATESMSNKQPSVKNTQCTGLG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGGKNLSLLKQERDAALSVCAAKPIAPPTLSTTTPTLTPPAKRKLNLEEYKQRRCGGVGAVYPKPTPPKQAKIEVAAKRIAPTPVSKPTPSPKKAEIVNIVNSLKCPRTEQSSLPMDPITMAKNKVLRMLEMKRAQQLKIIDSRVSAKVPRVTKLPPLKDIVKDTYCMETEDPGTEIAPLSNKLHP-DYEEIIIVSASCNTDITIPPNQLSKAS--------------------------PRSLLKSSVLLYNISNGQDANKNMSNSLIASIQSEVARQTSNTTLSTIQSNATKVMSSADKNCQHGEDMVIMHLPKDRVRKTLVSIATQTDLQPEFPLLTLPPKRQSRERTRRNYRRRRTQGSGSNMSTSSSDFSSDCSSLVSHRSRSQYDSIDQLRNLDVAATCGGSIGNGGYSSRST--QRHRSSVSSSSYSENGQYRRRQRRTSYNKRRSRNQKRGSTSSSCSGSEKSDRERS-RSPHRKLRHSRSRSRSKSDTRYPNNNSSSNNNNRRGFFDRNVSQPAVEERRIVYVGRIEQETTKEILRRKFLPYGSIKQITIHYKENGMKYGFVTYERAQDAFTAIDT--SHRDSQISMYDISFGGRRAFCRSSYADLDNAGINNYNSYVFPKEAPAPNVVEDSFEALLLQVKAKLNAGKSPVGSSTLEAPSASGTVLQGHSQM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..:. .* . : *.. . : * * : . : * :. . * : . .: :*.: ** ::::..* : *:: :: *:: :.: :* :. .:* : :*. : .. * * :.* *: : .* * * :. : * . : : : :** : : : . : :.:. :*. : ... . ::**.: : .. * . .. :. * . :. . .. .: .:*. . . *. .: * .***::*. : . : * : . :: . : . . * .* * . . * * * : : .. ** . . : ..: . . . .. * : .:* *. .* : : .*: *: :: .:. : .. : . . . : * :. * * : * : : : ... . .: . * .* .* : : *. . : * ... ** : **. * :.. : * .. :*:.:. . . .. * ::** *. :*: ..*. .*::. * * *:****::***::. ::*: *: :* :*.*:: *:: :.:* .:**:**. : **::*::. : * *: . ::: : *:: : :*.*:*** :* * :. .: . .*::** :.: .*. ", "identical_positions": 113, "similar_positions": 274, "identity": "8.71%" }, { "cls_id": "homologset.agr.RGD:620926", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K960-1", "uniprot_id": "A0A0G2K960_RAT", "id": "A0A0G2K960-1", "name": "SAM domain-containing protein SAMSN-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKRKPSNASE-------------------------------------------KEKHQKPKRSSS------------------------------------------------------------------------------------------------------------------FGNFDRFR--------NNSISKSDD-------SIEVRDGELTNGSEEQSKTS---------------------NNGGSLG---------------------------------KKVRAISWTMKKKVGKKYIKALSEEKEEEIREETLQYRNSDPMIGTRTEKISLKASDS-------MDSLYSGQSSSSGITNCSDGTSNRDSFRLD--------DDSPYSGPFCGRARVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEE----------EAAPKKVKVPRSSRRENPQTLQEFLERIHLQEYTSAFLLNGYEALDDLKDIKESHLIELNIANPEDRARLLSAAESLLDEETAAEHEEEPVPLSSNPDI--------LSESQLDDCPRDSGCY--------------ISSGNSDNGKEDPESQSLPDMVQKISITEPSD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P57725-1", "uniprot_id": "SAMN1_MOUSE", "id": "P57725-1", "name": "SAM domain-containing protein SAMSN-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKRKPSNASD-------------------------------------------KEKHQKPKRSSS------------------------------------------------------------------------------------------------------------------FGNFDRFR--------NNSVSKSDD-------SIEVHDRELTNGSEEQSKTS---------------------SSGGSLG---------------------------------KKVRAISWTMKKKVGKKYIKALSEEKEEESGEEALPYRNSDPMIGTHTEKISLKASDS-------MDSLYSGQSSSSGITSCSDGTSNRDSFRLD--------DDSPYSGPFCGRAKVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVILEE----------EAAPKKIKVPRSRRRENHQTIQEFLERIHLQEYTSTLLLNGYETLDDLKDIKESHLIELNIADPEDRARLLSAAESLLDEETTVEHEKESVPLSSNPDI--------LSASQLEDCPRDSGCY--------------ISSENSDNGKEDLESENLSDMVQKIAITESSD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NSI8-1", "uniprot_id": "SAMN1_HUMAN", "id": "Q9NSI8-1", "name": "SAM domain-containing protein SAMSN-1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKRKPSNVSE-------------------------------------------KEKHQKPKRSSS------------------------------------------------------------------------------------------------------------------FGNFDRFR--------NNSLSKPDD-------STEAHEGDPTNGSGEQSKTS---------------------NNGGGLG---------------------------------KKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDS-------MDSLYSGQSSSSGITSCSDGTSNRDSFRLD--------DDGPYSGPFCGRARVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEE----------EAAPKKIKANRRSNSKKSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAENFLEEEIIQEQENEPEPLSLSSDIS-------LNKSQLDDCPRDSGCY--------------ISSGNSDNGKEDLESENLSDMVHKIIITEPSD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BH30-1", "uniprot_id": "A0A8M2BH30_DANRE", "id": "A0A8M2BH30-1", "name": "", "aln": "----------------MNLFCFTLDGSTDSLYEPAQIGQSSQDSLPRRPFSP---------------------------NCAKNMGLWSGSEPCIATKLPETHTSKTRESKTLEKAKKKSQLQSTSEDETTDHTGSDAHWPSTRKKDGLVNGKNHSAAEAAKDHHRSKLLSREEKEERGNSEKAVKNPCGQG------VNFEAWNPNRENSECRQQDLARRSEVEDEAQGTLKKIQKLVGGKKGGQNSMEEMRNSTEAAGNLTESN----------------------SKHHSPVITCISLTKKAEKKPTRAPSRPTAQSQQPLQENDTLPELFYEYYSSVAFSPAWDTS----------------------------------------------THTCHRSTAEQVMYNFNFTLPRDTDWDRYEDLFQRLDPYKRYQQDTWITHSVMELDKPDALRSTSFGIFDRQQPNQVKAEDKVESLPVESPEVDP----------SKSGGLS---------------------------------KKMKNISLTMRKKMGRKYTKALSEETGEENEAAAADVVDSTLAKGNN---HSSNSVES-------LFSLHSGQSSSSGVTSGSEGYSNRDSLRLE--------EEVPFAGQFCGKAKVHTDFVPSPYDTESLKLKVGDVIDIINKPPMGIWTGMLNGKVGNFKFIYVDVLVEE----------ITPQPRIRAHRRSRRPRPKTLQELLERLNLEEHISSLLLNGYQTVEDLRDLKEQHLVELNMTDPEHRHRLLAAAENLLDSEYNNQSHGETNEEPKSPSE--------EEKTELNDCPRDSGCY--------------IGSDCSDNSKEDTES-------QQTPLSPPAP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHV7-1", "uniprot_id": "A0A0B4KHV7_DROME", "id": "A0A0B4KHV7-1", "name": "Sterile alpha motif domain-containing protein 5", "aln": "MAVSNIVCEWLRALGLAQYAESFLDNGYDDLEICKQVGDPDLDAIGVENPAHRHKLLKSIRSLREKGAASVYFMLNDPNSLSGSMEILCETPPNNELELVLREQLETDGVRLTAHPYSTPPSSCLSDKEEDEIYGFGYGVFAPRVARGGLTQQQQLLQQQTLQTQQSIQQQQQQMQQQQQQLPIVPGQQQQGPHQHQTLPPNVAHLNFVQQNCLSPRSAYFYEFPPTAEGRETKKRTTLARLLKGLKTVNRRDRNNQQNGAQARAANDRLRHFQMINGGAGGQQHSFEETIHRLKVQEAMRKKEKFQREHEEILRDIRQGLLQMSRGEGRMDDTYMYDEALRTGGGMGIAGLGMPLGVGGNGGGGGAAHYAVSALHHQGHWYDEPPYESDPDDFLMAGLNCGPAATIQGGRVRFSNNRESTGVISLRSAGDISLPQRGPPRRGLIVPQQPPNPPTIIPLTHARSHDRESGDYAGSISDLQSVTSRFSTVSIGTNNCTARYRTLSGGIGESPSLSPSPSSDYEDIGVTRGHGCLPPSLLAAKAKKNGLPHGKANTICQKATVHHSGEMRSSAKEIGAFNENGRNFVATKDTSRDFSNSQDNTDRGSMSDQAFACSASSVESLPSASGSSTQALVRPGSPHSSISAEDRTSMASCICKAKALVDSLPNPYDKEALKFKKGDLIDVLSMNASGIWKGRCHGRVGHFKFINVEVLPEQRMKNSSSKTLAAGSRLANSGNGSHNGGPCSVEDLLIRIGLKEYTSVFVLNGYEDLELFKELEPADLDYLGILNQEHRAKLLTAVQLLHDIECSDVDIPGSSSENDEARLNNINMKHGASPFGRRHFPRDSGCYEGSPLPSSQTPTQAVNSTDESNSLDDVVTKCSSEIMKRVESARRCKDNPFKTTLPGGGRLGKKSFLGGNGLMADDTLTRGGLSEKSSDSGVSSSSLSSGPLKSSTXHLPTILAHELLLGVGSGMGMGLGLGTMSHGTTGTLTPHGVATATSPTAHSAPLGNICNTLPHAPSSSGGGGVSSSMASNLPLNRNLVMLRNHLRKNTGGSITGNGGVGASGVGAQLLQDQDDRLEDQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. *: :: . :. : . : : : : .. . . .*.:. * . :. :.: :* * * .. :. ... . . :. . .: .:** :.* *.: .* :: . . :*:. .* *.***.::**:* **:**:: . *:*.* :.:**:**** *:*: *: : . . . :::::* *: *:*: * ::****: :: ::::: .* *.: : :.* :**:*.: : : * . .. . . ******* :.* ..*. :* : :: : . ", "identical_positions": 62, "similar_positions": 128, "identity": "5.74%" }, { "cls_id": "homologset.agr.RGD:620927", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60714-1", "uniprot_id": "S27A1_MOUSE", "id": "Q60714-1", "name": "Long-chain fatty acid transport protein 1", "aln": "------------MRAPGAGTASVASLA----------------------------------LLWFLG--------------LPWTWSA---AAAFCVYVGGGGWRFLRIVCKTARRDLFGLSVLIRVRLELRRHRRAGDTIPCIFQAVARRQPERLALVDASSGICWTFAQLDTYSNAVAN---------LFRQLGFAPGDVVAVFLEGRPEFVGLWLGLAKAGVVAALLNVNLRREPLAFCLGTSAAKALIYGGEMAAAVAEVSEQLGKSLLKFCSGDLGPESILPDT-------QLLDPMLAEAPTTPLAQAPGKG-MDDRLFYIYTSGTTGLPKAAIVVHSRYYRIAAFGHHSYSMRAADVLYDCLPLYHSAGNIMGVGQCVIYGLTVVLRKKFSASRFWDDCVKYNCTVVQYIGEICRYLLRQPVRDVEQRHRVRLAVGNGLRPAIWEEFTQRFGVPQIGEFYGATECNCSIANM---DGKVGSCGFNSRILTHVYPIRLVKVNEDTMEP---LRDSEGLCIPCQPGEPG-LLVGQINQQDPLRRFDGYVSDSATNK-KIAHSVFRKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEAVLSRLLG--QTDVAVYGVAVPGVEGKAGMAAIADPHSQLDPNSMYQELQK-----VLASYARPIFLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFFLDLKQGRYVPLDERVHARICAGDFSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97849-1", "uniprot_id": "S27A1_RAT", "id": "P97849-1", "name": "Long-chain fatty acid transport protein 1", "aln": "------------MRTPGAGTASVASLG----------------------------------LLWLLG--------------LPWTWSA---AAAFGVYVGSGGWRFLRIVCKTARRDLFGLSVLIRVRLELRRHRRAGDTIPRIFQAVAQRQPERLALVDASSGICWTFAQLDTYSNAVAN---------LFLQLGFAPGDVVAVFLEGRPEFVGLWLGLAKAGVVAALLNVNLRREPLAFCLGTSAAKALIYGGEMAAAVAEVSEQLGKSLLKFCSGDLGPESVLPDT-------QLLDPMLAEAPTTPLAQAPGKG-MDDRLFYIYTSGTTGLPKAAIVVHSRYYRIAAFGHHSYSMRANDVLYDCLPLYHSAGNIMGVGQCIIYGLTVVLRKKFSASRFWDDCVKYNCTVVQYIGEICRYLLRQPVRDVERRHRVRLAVGNGLRPAIWEEFTQGFGVRQIGEFYGATECNCSIANM---DGKVGSCGFNSRILTHVYPIRLVKVNEDTMEP---LRDSQGLCIPCQPGEPG-LLVGQINQQDPLRRFDGYVSDSATNK-KIAHSVFRKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEAVLSRLLG--QTDVAVYGVAVPGVEGKSGMAAIADPHNQLDPNSMYQELQK-----VLASYAQPIFLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFFLDLKQGRYLPLDERVHARICAGDFSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PCB7-1", "uniprot_id": "S27A1_HUMAN", "id": "Q6PCB7-1", "name": "Long-chain fatty acid transport protein 1", "aln": "------------MRAPGAGAASVVSLA----------------------------------LLWLLG--------------LPWTWSA---AAALGVYVGSGGWRFLRIVCKTARRDLFGLSVLIRVRLELRRHQRAGHTIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVAN---------LFRQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDT-------HLLDPLLKEASTAPLAQIPSKG-MDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANM---DGKVGSCGFNSRILPHVYPIRLVKVNEDTMEL---LRDAQGLCIPCQAGEPG-LLVGQINQQDPLRRFDGYVSESATSK-KIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLG--QTDVAVYGVAVPGVEGKAGMAAVADPHSLLDPNAIYQELQK-----VLAPYARPIFLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGAFAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KVJ6-1", "uniprot_id": "Q7KVJ6_DROME", "id": "Q7KVJ6-1", "name": "long-chain-fatty-acid--CoA ligase", "aln": "MCTAGVVDGGAGATTGGADAADNSGAAPAPSSTALNPPQVSISMNEPENLKPPAKSNFRRYLQWILAPVLTAISGLILYYQGPWYGVATLYAALISILLVRPGWRWFYIAAVTTPRDTVALFAYIRVLLFIKRQERKNLNIGDIFESNVARQPDKLAIVSESQ--QWTFRQVNEHSNRVAN---------VFHSHGYKKGDVVGLLLENRAEFVATWLGLSKIGVITPLINTNLRGASLQHSITVGQCTALIYGASFRSAVMDIAKDLPAHVGLYQFNDESNQEVVASEGLSQGLAQQLNGLLETAAKDKVAAGASRADHHDKLVYIYTSGTTGLPKAAVITHSRYFFIAAGIHYTLGFKDQDVFYTPLPLYHTAGGVMSMGQALLFGSTVVIRKKFSASGYFSDCARFQCTVGQYIGEMARYILATPSAPHDRNHQVRMVFGNGLRPQIWPQFVERFGIRKVGEFYGATEGNANIMNN---DSTVGAIGFISRILPQIYPISIIKADPHTGEP---LRNSQGLCERCEADEPG-VFVGKIVRGNPCREFLGYVDQKASSK-KVVHDVFSKGDMAFISGDLLVADERGYLYFKDRTGDTFRWKGENVSTSEVEAQLSNLAG--YKDVIVYGVSIPNTEGRAGMAAIYDPTREVNVSQLGVELAK-----SLPNYARPQFLRFLRKIDLTGTFKLRKVELQQQGFNPEIIDDELFYAQP-DGVYAPLTPSVYERIVRNELRF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38225-1", "uniprot_id": "FAT1_YEAST", "id": "P38225-1", "name": "Very long-chain fatty acid transport protein", "aln": "------------MSPIQVVVFALSR-----------------------------------IFLLLFR----------------LIKLIITPIQKSLGYLFGNYFDELDRKYRYKEDWYIIPYFLKSVFCYIIDVRRHRFQNWYLFIKQVQQNGDHLAISYTRPMAEKGEFQLETFTYIETYNIVLRLSHILHFDYNVQAGDYVAIDCTNKPLFVFLWLSLWNIGAIPAFLNYNTKGTPLVHSLKISNITQVFIDPDASNPIRESEEEIKNALPDVKLNYLEEQDLMHELLNS----QSPEFLQQDNVRTPLGLTDFKP-----SMLIYTSGTTGLPKSAIMSWRKSSVGCQVFGHVLHMTNESTVFTAMPLFHSTAALLGACAILSHGGCLALSHKFSASTFWKQVYLTGATHIQYVGEVCRYLLHTPISKYEKMHKVKVAYGNGLRPDIWQDFRKRFNIEVIGEFYAATEAPFATTTFQKGDFGIGACRNYGTIIQWFLSFQQTLVRMDPNDDSVIYRNSKGFCEVAPVGEPGEMLMRIFFPKKPETSFQGYLGNAKETKSKVVRDVFRRGDAWYRCGDLLKADEYGLWYFLDRMGDTFRWKSENVSTTEVEDQLTASNKEQYAQVLVVGIKVPKYEGRAGFAVIKLTDNSLDITAKTKLLNDSLSRLNLPSYAMPLFVKFVDEIKMTDNHKILKKVYREQKLPKGLDGNDTIFWLKNYKRYEVLTAADWEAIDAQTIKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : :: : : : . * : .* :* . :: ::**: *:: .: : :. . . ** *.: .:. ** **.* : * ..::* * : .* ..: . . :: . . .: : .: : . : :: . : : : :. : . ***********:*:: : . : : ...: :**:*::. ::. : .* :.: :***** ::.: .* **:**:.**:* * :: *:*::. ****** ** :* : *.: :****.*** . * :*: . *: . .: . .. : *:::*:* . .*** ::: : .* * **:.: .* *:.:.** :** : .**:* ** * ** ** ******:.*****:*** *: :* * *: :* **::*:*.: . :: . * . *. ** * *:::: ::. *...*: * :.: : .: :: * * * : :", "identical_positions": 131, "similar_positions": 188, "identity": "17.68%" }, { "cls_id": "homologset.agr.RGD:620928", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28573-1", "uniprot_id": "SC6A7_RAT", "id": "P28573-1", "name": "Sodium-dependent proline transporter", "aln": "MKKLQEAHLRKPVTPDLLMTPSDQGDVDLDVDFAADRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSNLPWEHCG----------NWWNTERCLEHRGPKDGNGALPLNLSSTVSPSEEYWSRYVLHIQGSQGIGRPGEIRWNLCLCLLLAWVIVFLCILKGVKSS--GKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVIYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPAWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAIDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEEESMM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGE7-1", "uniprot_id": "SC6A7_MOUSE", "id": "Q6PGE7-1", "name": "Sodium-dependent proline transporter", "aln": "MKKLQEAHLRKPITPDLLMTPSDQGDVDLDVDFAADRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSNLPWEHCG----------NWWNTELCLEHRGPKSGNGVLPLNLSSTVSPSEEYWSRYVLHIQGSQGIGRPGEIRWNLCLCLLLAWVIVFLCILKGVKSS--GKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPAWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEEESMM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99884-1", "uniprot_id": "SC6A7_HUMAN", "id": "Q99884-1", "name": "Sodium-dependent proline transporter", "aln": "MKKLQGAHLRKPVTPDLLMTPSDQGDVDLDVDFAAHRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCG----------NWWNTELCLEHRVSKDGNGALPLNLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSS--GKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALMVYSIVKYQPSEYGSYRFPPWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEE-SMM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLY5-1", "uniprot_id": "Q9VLY5_DROME", "id": "Q9VLY5-1", "name": "Transporter", "aln": "-------MASKPFSPDLN------------------RGNWEKPTDYIFACFGLALKLD-IFVASFWFFFNTGIFGMVPYLMYMVIYLVPIMVIHSYMGQFSSSGFISAFRLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPWSCEGFKSWQNDTIAKWSICNATIAEEVAKETENDTYFYITNIHVPSVLYFKSHFESFQNDSELN-DYEISWHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPGAHLGLKNYMTPSIEEFVVG--TSSTFIMALQAFGAGWGSVITLSSFNGFKTNIMSYSWIISFGQIFIYIMFGMVSFMLEHYF-LGLPKPLFETQVINHWVLFLSSASALSSLGWPNLWTFIYYTMLLMAALIVITTQIFTILQSLFDEFEQLRAKKQEVTLGLIG-GLAVCSLYFCTNHGVLYFAILS-IDAIFSQTLLHLLLLLVVLWVYGRDRFQKDIKFMLGQPFASWKVFILRFVAPPTLVICLVLEIKMCLEEHSYSS---SVLHFMAIILVGLPILAIPAYGFYYIHQRPGSISELFR-----ATDWYPVEMEYR---------------------QQYGELVQKSEMTHQLFDRTEEVN-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.:*** **** *::::*:* .: *. :: .: : * * :***:: :.* :*::.:. :***** * ::.:::****** * . *::. : ***.:: * *:::: *: . ***. * :* : : .. .*. :. : :: ** *:. :. :*... :. ** *:*. : *.*. : : : * :.: ** : : . . :**: :** : **** *:: *:**.:..:: . .: : : ::*.*:*.::*::*:* *: ** ::*:::*: : *: *:. * : *: * *: :. . : *: ..*:: * . :*:*::: *** .* : : **: :: *** *: * *** .: : .* : *: *: ::.:*. .* *. :: : *.* *** :** :**::*** . : *::*.**: :* .* .. * . .::.*:: *. * *** : : :. **: * :: * ** * * * ::** :.. .: : :: . * : ", "identical_positions": 150, "similar_positions": 208, "identity": "23.11%" }, { "cls_id": "homologset.agr.RGD:620929", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28360-1", "uniprot_id": "MSX1_HUMAN", "id": "P28360-1", "name": "Homeobox protein MSX-1", "aln": "MAPAADMTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LJN7-1", "uniprot_id": "A0ABK0LJN7_RAT", "id": "A0ABK0LJN7-1", "name": "Homeobox protein MSX-1", "aln": "MAPAAAMTSLPLGVKVEDSAFAKPAGGGAGQAPGAAAATATAMGTDEEGAKPKVPASLLPFSVEALMADHRKPGAKESVLVASEGAQAAGGSVQHLGTRPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKLDRTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYSASGPFQRAALPVAPVGLYTAHVGYSMYHLT", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ***************.***********.******:***:*********..**********************.*..***.******.* **. **************************************** :***********************************************************************************************************************************.******************************", "identical_positions": 285, "similar_positions": 14, "identity": "94.06%" }, { "cls_id": "homologset.agr.RGD:620930", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1N1-1", "uniprot_id": "F16P2_RAT", "id": "Q9Z1N1-1", "name": "Fructose-1,6-bisphosphatase isozyme 2", "aln": "---------MTD-RSPFETDMLTLTRYVMEKGRQAK-GTGELTQLLNSMLTAIKAISSAVRKAGLANLYGIAGSVNVTGDEVKKLDVLSNSLVINMLQSSYSTCVLVSEENKEAVITAKERRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTTEDEPSEKDALQPGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDIRIKKKGKIFSLNEGYAKYFDAATAEYVQKKKFP--EDGSAPYGARYVGSMVADVHRTLVYGGIFMYPANQKSPNGKLRLLYECNPVAYIIEQAGGMATTGT-QPVLDVKPESIHQRVPLILGSPEDVQEYLSCVQRNQAGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70695-1", "uniprot_id": "F16P2_MOUSE", "id": "P70695-1", "name": "Fructose-1,6-bisphosphatase isozyme 2", "aln": "---------MTD-RSPFETDMLTLTRYVMEKGRQAK-GTGELTQLLNSMLTAIKAISSAVRKAGLANLYGISGSVNVTGDEVKKLDVLSNSLVINMLQSSYSTCVLVSEENKEAVITAQERRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTTEDEPSEKDALQPGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVRIKKKGKIFSLNEGYAKYFDAATAEYVQKKKFP--EDGSEPYGARYVGSMVADVHRTLVYGGIFMYPANQKSPNGKLRLLYECNPVAYIIEQAGGMATTGT-QPVLDVKPESIHQRVPLILGSPEDVQEYLSCVQRNQAGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00757-1", "uniprot_id": "F16P2_HUMAN", "id": "O00757-1", "name": "Fructose-1,6-bisphosphatase isozyme 2", "aln": "---------MTD-RSPFETDMLTLTRYVMEKGRQAK-GTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGSVNVTGDEVKKLDVLSNSLVINMVQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTSEDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFP--EDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGT-QPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQAGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0U1RVK6-1", "uniprot_id": "A0A0U1RVK6_DROME", "id": "A0A0U1RVK6-1", "name": "Fructose-1,6-bisphosphatase isozyme 2", "aln": "MAASSGDSKMTQQRPAFDSNAMTLTRFVLQEQRKFKSATGDLSQLLNSIQTAIKATSSAVRKAGIAKLHGFAGDVNVQGEEVKKLDVLSNELFINMLKSSYTTCLMVSEENENVIEVEVEKQGKYIVCFDPLDGSSNIDCLVSIGSIFAIYRKKSDGPPTVEDALQPGNQLVAAGYALYGSATAIVLGLGSGVNGFTYDPAIGEFVLTDPNMRVPEKGKIYSINEGYAADWEDGVFNYIAAKKDP--AKG-KPYGARYVGSMVADVHRTIKYGGIFIYPATKSAPSGKLRLLYECVPMAYLMIQAGGLASDGK-ISILDIVPKKIHERSPIFLGSKSDVEEALSYLK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P09201-1", "uniprot_id": "F16P_YEAST", "id": "P09201-1", "name": "Fructose-1,6-bisphosphatase", "aln": "-MPTLVNGPRRDSTEGFDTDIITLPRFIIEHQKQFKNATGDFTLVLNALQFAFKFVSHTIRRAELVNLVGLAGASNFTGDQQKKLDVLGDEIFINAMRASGIIKVLVSEEQEDLIVFPTN-TGSYAVCCDPIDGSSNLDAGVSVGTIASIFRLLPDSSGTINDVLRCGKEMVAACYAMYGSSTHLVLTLGDGVDGFTLDTNLGEFILTHPNLRIPPQKAIYSINEGNTLYWNETIRTFIEKVKQPQADNNNKPFSARYVGSMVADVHRTFLYGGLFAYPCDKKSPNGKLRLLYEAFPMAFLMEQAGGKAVNDRGERILDLVPSHIHDKSSIWLGSSGEIDKFLDHIGKSQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *::: :**.*::::. :: * .**::: :**:: *:* * ::*:* :.:* *::* *. *:: ******.:.:.** :::* ::****::: : : *.* ** **:*****:*. .*:*:* :*:* .:. : :*.*: *.::*** **:***:* :.* *.**: * *. :***:*.. :::: : *:*:*** : :: :: * * .. *:.**************: ***:* **. :.:*.********. *:*::: **** * . :**: *. **:: .: *** :::: * : ", "identical_positions": 124, "similar_positions": 118, "identity": "35.13%" }, { "cls_id": "homologset.agr.RGD:620931", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51146-1", "uniprot_id": "RAB4B_RAT", "id": "P51146-1", "name": "Ras-related protein Rab-4B", "aln": "MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDISLRQLRQPRSAQAVAPQPCGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZR1-1", "uniprot_id": "RAB4B_MOUSE", "id": "Q91ZR1-1", "name": "Ras-related protein Rab-4B", "aln": "MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDISLRQLRQPRSAQAVAPQPCGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61018-1", "uniprot_id": "RAB4B_HUMAN", "id": "P61018-1", "name": "Ras-related protein Rab-4B", "aln": "MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQLRQPRSAQAVAPQPCGC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68EK7-1", "uniprot_id": "RAB4B_DANRE", "id": "Q68EK7-1", "name": "Ras-related protein Rab-4B", "aln": "MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARSIPNKIESGELDPERMGSGIQYGDASLRQIRQPRGSAAQTKQQCNC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:***********************************************************************************************:*: **************:**********.:***************************************:* ***:***************** ****:****.: * : * *.*", "identical_positions": 193, "similar_positions": 13, "identity": "90.61%" }, { "cls_id": "homologset.agr.RGD:620932", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q03356-1", "uniprot_id": "MSXB_DANRE", "id": "Q03356-1", "name": "Homeobox protein MSH-B", "aln": "-------------------------------------------------------------------------------------MNSPKGPVETTSQEKSESDSEESQKPRDMTADTG-----HKAKKTYLPFSVESLMAKSSCQQVACSP---ALQHQRMGHGQDLVRT--YFVEKAKVSVDTLSS-----------------------------VSDSLNDDSEELSDKEQSTWSNSSSFT--------------------------------------------------------------------SPPRHPS--------------PTP----------------------------------------------------------------------------CTLRKHKTNRKPRTPFSTSQLLSLERKFRQKQYLSIAERAEFSNSLNLTETQVKIWFQNRRAKAKRLQEAELEKFKCASKPLLAP-FALPFPLGS---PSSLYGPPASFPRP-VPMPGLFNGPVS-YGMYYLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01703-1", "uniprot_id": "MSXC_DANRE", "id": "Q01703-1", "name": "Homeobox protein MSH-C", "aln": "------------------------------------------------------------------------------MAPLSSMMNSLQGPLSQEGKLQERKSDKEDAQSNDKAAVKG-----CKGKALSLPFSVESLISDRTSSRTLYTSSEAGIISPTSGADERLKLSPMALYADRKIPVESVSN-----------------------------LSDCKRGDMEELSDKGQSGWFQTTSYT--------------------------------------------------------------------SPPRHSS--------------PPP----------------------------------------------------------------------------CTLRKHKNNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSNSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKLATKPLLPA-FAFPFPLGTHVGSPPLYGPSSSFPRPALPVPGLFGGPVT-YGMYYLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3V8C7-1", "uniprot_id": "G3V8C7_RAT", "id": "G3V8C7-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------MARATLDMNAAGLEARGG-----GHIEQGPLPFSVESLLEA-----------------------------------------ERVRG-----------------------------SESGELGEERPPGASKPGAWPPPVAHS--------------------------------------------------------------------CPPRAPS--------------PPP----------------------------------------------------------------------------CTLRKHKTNRKPRTPFTTAQLLALERKFHQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKLTAKPLLPAAFALPFPLGT-----QLHSSAATFGGN--AVPGILAGPVAAYGMYYLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70354-1", "uniprot_id": "MSX3_MOUSE", "id": "P70354-1", "name": "Homeobox protein MSX-3", "aln": "-----------------------------------------------------------------------------------------------------MARATFDMNAAGLEARGG-----GHTEHGPLPFSVESLLEA-----------------------------------------ERVPG-----------------------------SESGELGVERPLGASKPGAWPPPVAHS--------------------------------------------------------------------CPPRAPS--------------PPP----------------------------------------------------------------------------CTLRKHKTNRKPRTPFTTAQLLALERKFHQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKLAAKPLLPAAFALPFPLGT-----QLHSSAATFGGN--AVPGILAGPVAAYGMYYLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03372-1", "uniprot_id": "HMSH_DROME", "id": "Q03372-1", "name": "Muscle segmentation homeobox", "aln": "MLKLSPASMTVTGLRQTMTSPTVPPSSNTPAGNLIITSSSSNSGSNSGSNMSSGNMTSSNLTNLSPSHPAGLNALASPTSPSALLLAHQQHLLQQHQQHQQQQQQQQQAAALQLAAVHPPAHHLHKTTSRLSNFSVASLLADTRPRTPPNQAADGPQNLTSSAATSPISQASSTPPPPPASAAAQVPANTFHPAAVAHHAHLLQAAHAAAAAHAQHQAMAAQLRQQQQQADARANSPPASTSSTPSSTPLGSALGSQGNVASTPAKNERHSPLGSHTDSELEYDEEMLQDHEADHDEEEDSIVDIEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQSTILSPAALASGHVPIRPTPFSALAAAAVAWTGMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEPPRIKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKRLQEAEIEKIKMAA-------------LGR------------GAPGAQWAMAGYFHPSLMHLG-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : *** **: : . . . . : : .* .. *.* *.***** ********:* ***:**:**::*************.** ************************:**:* :: ** .:.* : .: * ", "identical_positions": 77, "similar_positions": 32, "identity": "14.13%" }, { "cls_id": "homologset.agr.RGD:620933", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY93-1", "uniprot_id": "DCTP1_MOUSE", "id": "Q9QY93-1", "name": "dCTP pyrophosphatase 1", "aln": "MSTAGDGERGTVGQEDSAAARPFRFSPEPTLEDIRRLHAEFAAERDWEQFHQPRNLLLALVGEVGELAELFQWKSDTEPGPQAWPPKERAALQEELSDVLIYLVALAARCHVDLPQAVISKMDTNRQRYPVHLSRGSACKYTDLPRGTISENQAVGAGDPASELRDQAST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91VC0-1", "uniprot_id": "DCTP1_RAT", "id": "Q91VC0-1", "name": "dCTP pyrophosphatase 1", "aln": "MSQAGTGVCGNGGQEDSAAAGPFSFSPEPTLEDIRRLHAEFAAERDWEQFHQPRNLLLALVGEVGELAELFQWKSDAEPGPQAWQPKERAALQEELSDVLIYLVALAARCHVDLPRAVISKMDTNRQRYPVHLSRGSACKYTDLPRGTLSENEAVGSGDPASELGNQAST", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H773-1", "uniprot_id": "DCTP1_HUMAN", "id": "Q9H773-1", "name": "dCTP pyrophosphatase 1", "aln": "MSVAGGEIRGDTGGEDTAAPGRFSFSPEPTLEDIRRLHAEFAAERDWEQFHQPRNLLLALVGEVGELAELFQWKTDGEPGPQGWSPRERAALQEELSDVLIYLVALAARCRVDLPLAVLSKMDINRRRYPAHLARSSSRKYTELPHGAISEDQAVGPADIPCDSTGQTST", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** * * **:**. * **************************************************:* *****.* *:***********************:**** **:**** **:***.**:*.*: ***:**:*::**::***..* ..: .*:**", "identical_positions": 126, "similar_positions": 25, "identity": "74.12%" }, { "cls_id": "homologset.agr.RGD:620934", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20689-1", "uniprot_id": "MYLK2_RAT", "id": "P20689-1", "name": "Myosin light chain kinase 2, skeletal/cardiac muscle", "aln": "------------------------------------------------------------------------------------------MATENGAVELGTQSLSTDHPPTDAAGDGSPASEKEP-------SLPDTEKDLGPTNTKKDPGAPDPKKNPDPPSLKKTP-EAPGPEK-KGDSAPASASNQGPSGEGDGGGGPAEG----GTGPPAVLPQPTATADASIQKLDATQAPSGNQESGEAKAGKKAAECR--EAGRRGSPAFLHSPSCPAIISCSEKTLAM-------KP-------------LSETTELIFAGVSETPD--PQDPGPAKDEGGTNTLADGKEE---AEAGQAEQAKVQGDTSQRIGFQAVPSERAE-VGQALCLTAKEED-----------------------------------CFQILDDCPPPPAPFPHRIVELRTG-NVSSEFSMNSKEALGGGKFGAVCTCTERSTGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYSAIETSHEIILFMEYIEGGELFERIVDEDYQLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSLGVITYMLLSGLSPFLGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFVSNLITKDQSARMSAEQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGALMALGV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCR8-1", "uniprot_id": "MYLK2_MOUSE", "id": "Q8VCR8-1", "name": "Myosin light chain kinase 2, skeletal/cardiac muscle", "aln": "------------------------------------------------------------------------------------------MTTENGAVELGSQSLSTEQTPKAAAGDGPSASEKEP-------SAPATEKDLSPPNAKKDPGAPDPKNNPDPPSLKKDPAKAPGPEK-KGDPVPASASSQGPSGEGDGGGGPAEG----SEGPPAALPLPTATAEASIQKLDPTQAPSGNQGSGEAKAGKKAAECR--EAGRRGSPAFLHSPSCPAIISCSEKTLAV-------KP-------------LSETTDLVFTGVSVTPD--PQDPGPVK-AGGTNALAEKKKEEAEKASGQAGQAKVQGDTPQRIGFQAVPSERVE-VGQALCLTAREED-----------------------------------CFQILDDCPPPPAPFPHRIVELRTG-NVNSEFSMNSKEALGGGKFGAVCTCTERATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIETSHEIILFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSLGVITYMLLSGLSPFLGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFVSNLLTKDQSARMSAEQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGALMALGV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1R3-1", "uniprot_id": "MYLK2_HUMAN", "id": "Q9H1R3-1", "name": "Myosin light chain kinase 2, skeletal/cardiac muscle", "aln": "------------------------------------------------------------------------------------------MATENGAVELGIQNPSTDKAPKGPTGERPLAAGK-------------------------DPGPPDPKKAPDPPTLKKDA-KAPASEKGDGTLAQPSTSSQGPKGEGDRGGGPAEG----SAGPPAALPQQTATPETSVKKPKAEQGASGSQDPGKPRVGKKAAEGQ--AAARRGSPAFLHSPSCPAIISSSEKLLAK-------KP-------------PSEASELTFEGVPMTHS--PTDPRPAKAEEGKNILAESQKEVGEKTPGQAGQAKMQGDTSRGIEFQAVPSEKSE-VGQALCLTAREED-----------------------------------CFQILDDCPPPPAPFPHRMVELRTG-NVSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGALMALGV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9N0-1", "uniprot_id": "A0AB13A9N0_DANRE", "id": "A0AB13A9N0-1", "name": "", "aln": "MSLKDSMKCPVPPSNPTTLEAKVDDLRLKVELLLGSSRSCSMCGTCAQHRALQETLTSQLSTQTRLLDSLEKKVMEMRVALEDLTRGLEDRQCERVSVPLVALQRRKSLPVRSSAEEVYICLDRDRKTMPHAFNKPSEKGILLEVNENNGTRREDHQAKKDSTEVKVEPTLPIKRENGTSSVTPRSEQTQKMNKTENKSMPPTQNHVLIPIRTPAIASQKTEAQEIRKVPPPNIKVPVAAAVIIPNTTGQTCTESVNVTPANHILPKTTVTPAAPPLVNNNTPKLTVSEVPKDFKPSHKYPQTSLPPSVAAQRSEQTPVNMPTTKTTTPQDAALFPPTHKPPKTVGLSVTTATKEASSLRQVHSCPNSLQRLQVPGLKADLVHTVTSTLTSKKRATETVGAAKLTSDGIQIKISSATDKNSAQTKSYNPPKLCFKVIDDVSPQPAPFAHRFVALKSSPPPCDTFSIHTREVLGGGRFGKVHKCTETRTGMRLAAKIINTRNSKERDMALNEMQVMNQLSHPNILQLYEAFEVKNQVVLILEYVEGGELFERIVDESSPLTEVDAMVFVKQICEGVQYMHQMYVLHLDLKPENILLVNRSSHQVKIIDFGLARRYKPREKLKVSFGTPEFLAPEVVNFDFVSFPTDMWTLGVVTYMLLSGLSPFLGDDDGQTLNNVLMGNWYFDEDAFEHVSADARDFVSNLLIRERSGRMSATQCLKHPWLNNIFEKAKSSNIVLKSQVLLKKYMARRLWKKNYIAIAAANRFKKIGSSGSLTSLGI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. :* * . .. . .: : . : .. * : *.. :* . . *: . . * ..* . : . *::. .** . * : : : . . .*:..:* ...: * :*:.*.::. . *: ** :: :: .:. * * *. . . ... *.: :: : : . .: :: . * .:* . : : **:::** .* ****.**:* *::. . **::::*.****:** * .* * **::****:*:.:..*:::*.* *::*****.* *::*** *:*. ::::*::**:************. *****:****:***:*: :**:* ************ ** :.* ************:*.*****.*******:*****:* :* ****::**:**************** :****** .******::** ** :*:******: ::: .**.* *** ******: **** .* ****:*****: :* ****:**::********.***:* :**:", "identical_positions": 245, "similar_positions": 170, "identity": "31.53%" }, { "cls_id": "homologset.agr.RGD:620935", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923I8-1", "uniprot_id": "CRY2_RAT", "id": "Q923I8-1", "name": "Cryptochrome-2", "aln": "------------------------------------------------------MAAAAVVAATVPVQSMGADGASSVHWFRKGLRLHDNPAL---------LAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQP-------ADVFPRLFKEWGVTRLT-----FEYDSEPFGKERDAAIMKMAKEAG-VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKK-PVGAVSSQHMEN-CRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALVRLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWD-----LYRKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDR-MEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCS-AFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAANCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLWASVPSCVEDLSHPVAEPGSSQAGSISNTGPRPLSSGPASPKRKLEAAEEPPGEELSKRARVTVTQMPAQEPPSKDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R194-1", "uniprot_id": "CRY2_MOUSE", "id": "Q9R194-1", "name": "Cryptochrome-2", "aln": "------------------------------------------------------MAAAAVVAATVPAQSMGADGASSVHWFRKGLRLHDNPAL---------LAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQP-------ADVFPRLFKEWGVTRLT-----FEYDSEPFGKERDAAIMKMAKEAG-VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKK-PAVAVSSQQMES-CRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWD-----LYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDR-MEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCS-AFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPGSSQAGSISNTGPRALSSGPASPKRKLEAAEEPPGEELTKRAR--VTEMPTQEPASKDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q49AN0-1", "uniprot_id": "CRY2_HUMAN", "id": "Q49AN0-1", "name": "Cryptochrome-2", "aln": "-----------------------------------------------------MAATVATAAAVAPAPAPGTDSASSVHWFRKGLRLHDNPAL---------LAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQP-------ADVFPRLFKEWGVTRLT-----FEYDSEPFGKERDAAIMKMAKEAG-VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQAIISRMELPKK-PVGLVTSQQMES-CRAEIQENHDETYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWD-----LYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDR-MEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCS-AFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKAFPSRYIYEPWNAPESIQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPSSSQAGSMSSAGPRPLPSGPASPKRKLEAAEEPPGEELSKRAR--VAELPTPELPSKDA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E8P0-1", "uniprot_id": "Q0E8P0_DROME", "id": "Q0E8P0-1", "name": "", "aln": "---------------------------------------------------------------------MDSQRSTLVHWFRKGLRLHDNPALSH---IFTAANAAPGKYFVRPIFILDPGILDWMQVGANRWRFLQQTLEDLDNQLRKLNSRLFVVRGKP-------AEVFPRIFKSWRVEMLT-----FETDIEPYSVTRDAAVQKLAKAEG-VRVETHCSHTIYNPELVIAKNLGKAPITYQKFLGIVEQLKVPKV-LGVPEKLKNMPTPPKDEVEQKDSAAYDCPTMKQLVKRPEELGPNKFPGGETEALRRMEESLKDEIWVARFEKPNTAPNSLEPSTTVLSPYLKFGCLSARLFNQKLKE-----IIKRQPKHSQPPVSLIGQLMWREFYYTVAAAEPNFDR-MLGNVYCMQIPWQEHPDHLEAWTHGRTGYPFIDAIMRQLRQEGWIHHLARHAVACFLTRGDLWISWEEGQRVFEQLLLDQDWALNAGNWMWLSAS-AFFHQYFRVYSPVAFGKKTDPQGHYIRKYVPELSKYPAGCIYEPWKASLVDQRAYGCVLGTDYPHRIVKHEVVHKENIKRMGAAYKVNREVR---------TGKEEESSFEEKSETSTSG-----------------KRKVRRATG----SAPKRKR----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05066-1", "uniprot_id": "PHR_YEAST", "id": "P05066-1", "name": "Deoxyribodipyrimidine photo-lyase, mitochondrial", "aln": "MKRTVISSSNAYASKRSRLDIEHDFEQYHSLNKKYYPRPITRTGANQFNNKSRAKPMEIVEKLQKKQKTSFENVSTVMHWFRNDLRLYDNVGLYKSVALFQQLRQKNAKAKLYAVYVINEDDWRAHMDSGWKLMFIMGALKNLQQSLAELHIPLLLWEFHTPKSTLSNSKEFVEFFKEKCMNVSSGTGTIITANIEYQTDELYRDIRLLENEDHRLQLKYYHDSCIVAPGLITTDRGTNYSVFTPWYKKWVLYVNNYKKSTSEICHLHIIEPLKYNETFELKPFQYSLP--DEFLQYIPKSKWCLPDVSEEAALSRLKDFLGTKSSKYNNEKDMLYLG----GTSGLSVYITTGRISTRLIVNQAFQSCNGQIMSKALKDNSSTQNFIKEVAWRDFYRHCMCNWPYTSMGMPYRLDTLDIKWENNPVAFEKWCTGNTGIPIVDAIMRKLLYTGYINNRSRMITASFLSK-NLLIDWRWGERWFMKHLIDGDSSSNVGGWGFCSSTGIDAQPYFRVFNMDIQAKKYDPQMIFVKQWVPELISSEN-------KRPE------------NYPKPLVDLKHSRERALKVYKDAM----------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :****:.***:** .* . : ::::: . : *: :*::*: .* :*: *:: . :. :. * .:**. : : : : * : : : :.: . : : . : .: : : :: * : : * : . *. * .:: .* ** *:.. * : . *: . ..: ** *: * :* **: : : : : :.. .. .:: :: **:*: * . * . ::* *:.:* : * *.** * :**** :* *:*:: :* .*.**:: :* :.*. * * * : *:* * : *.*.* : *.: : :*: : .:: **. ::::::*:* : . :**: :*. . :: ", "identical_positions": 81, "similar_positions": 149, "identity": "11.93%" }, { "cls_id": "homologset.agr.RGD:620936", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQD1-1", "uniprot_id": "RAB5A_MOUSE", "id": "Q9CQD1-1", "name": "Ras-related protein Rab-5A", "aln": "MANR----GAT------RPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPN-IVIALSGNKADLAN--------------------KRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLP--KNEPQNPGANSARGRG------VDLTEPAQPARSQCCSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0RC99-1", "uniprot_id": "RAB5A_RAT", "id": "M0RC99-1", "name": "Ras-related protein Rab-5A", "aln": "MANR----GAT------RPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFSRAKNWVKELQRQASPN-IVIALSGNKADLAN--------------------KRAVDFQEAQSYADDNSLLFMETSAKTPMNVNEIFMAIAKKLP--KNEPQNPGANSARGRG------VDLTEPAQPARSQCCSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20339-1", "uniprot_id": "RAB5A_HUMAN", "id": "P20339-1", "name": "Ras-related protein Rab-5A", "aln": "MASR----GAT------RPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLD--------DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPN-IVIALSGNKADLAN--------------------KRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLP--KNEPQNPGANSARGRG------VDLTEPTQPTRNQCCSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3I2-1", "uniprot_id": "RAB5_DROME", "id": "Q9V3I2-1", "name": "Ras-related protein Rab5", "aln": "MATTPRSGGASGTGTAQRPNGTSQ-NKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICIE--------DTVVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHKQASPN-IVIALAGNKADLSN--------------------IRVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIFLAIAKKLP--KNDGANNQGTSIRPTG------TETNRPTN----NCCK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36018-1", "uniprot_id": "YPT52_YEAST", "id": "P36018-1", "name": "GTP-binding protein YPT52", "aln": "---------------------------MLQFKLVLLGDSSVGKSSIVHRFVKDTFDELRESTIGAAFLSQSITIHPNDGNETKDVVIKFEIWDTAGQERYKSLAPMYYRNANAALVVYDITQEDSLQKARNWVDELKNKVGDDDLVIYLLGNKVDLCQETPSTETSPDSNEGGDEEQKVRAISTEEAKQYAQEQGLLFREVSAKTGEGVKEIFQDIGEKLYDLKKDEILSKQNRQIGGGNNGQVDINLQRPSTNDPTSCCS-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36017-1", "uniprot_id": "VPS21_YEAST", "id": "P36017-1", "name": "Vacuolar protein sorting-associated protein 21", "aln": "------------------MN-----TSVTSIKLVLLGEAAVGKSSIVLRFVSNDFAENKEPTIGAAFLTQRVTIN--------EHTVKFEIWDTAGQERFASLAPMYYRNAQAALVVYDVTKPQSFIKARHWVKELHEQASKD-IIIALVGNKIDMLQE--------------GGE---RKVAREEGEKLAEEKGLLFFETSAKTGENVNDVFLGIGEKIPLKTAEEQNSASNER-ESNNQ-RVDLNAAN-DGTSANSACSC", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36019-1", "uniprot_id": "YPT53_YEAST", "id": "P36019-1", "name": "GTP-binding protein YPT53", "aln": "------------------MDKHTAAIPTLTIKVVLLGESAVGKSSIVLRFVSDDFKESKEPTIGAAFLTKRITRD--------GKVIKFEIWDTAGQERFAPLAPMYYRNAQAALVVFDVTNEGSFYKAQNWVEELHEKVGHD-IVIALVGNKMDLLNN--------------DDENENRAMKAPAVQNLCERENLLYFEASAKTGENIYQIFQTLGEKVPCPEQNTRQSSTHDRTITDNQ-RIDLESTTVESTRETGGCNC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:****:::*****:* ***.. * * :*.*******:: : . .:************: .*******.*:**:**:*: : *: :*: **.**:.:.. : ::* * *** *: : * : :. .: :.**: *.**** .: ::* :.:*: : . : *. ", "identical_positions": 72, "similar_positions": 59, "identity": "27.48%" }, { "cls_id": "homologset.agr.RGD:620937", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97679-1", "uniprot_id": "MLH1_RAT", "id": "P97679-1", "name": "DNA mismatch repair protein Mlh1", "aln": "--MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMTENCLDAKSTNIQVIVREGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQTFEDLAMISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLQAPPKPCAGNQGTLITVEDLFYNIITRKKALKNPSEEYGKILEVVGRYSIHNSGISFSVKKQGETVSDVRTLPNATTVDNIRSIFGNAVSRELIEVGCE--DKTLAFKMNGYISNANYSVKKCIF-LLFINHRLVESAALKKAIEAVYAAYLPKNTHPFLYLILEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAG------PSGEAVKSTTGIASSSTSGSGDKVHAYQMVRTDSRDQKLDAFMQPVSRRLPSQPQD--PVPGNRTEGSPEKAMQKDQEISELPAPMEAAADSASLERESVIGASEVVAPQRHPSSPGSSRKRHPEDSDVEMMENDSRKEMTAACYPRRRIINLTSVLSLQEEINDRGHETLREMLRNHTFVGCVNPQW--ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLPEPAPLFDFAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAKMLADYFSVEIDEEGN--------LIGLPLLIDSYVPPLEGLPIFILRLATEVNWDEE-ECFESLSKECAVFYS--IRKQYILEESALSGQQSDMPGSPSKPWKWTVEHIIYKAFRSHLLPPKHFTEDGNVLQLANLPDLCKVFERC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JK91-1", "uniprot_id": "MLH1_MOUSE", "id": "Q9JK91-1", "name": "DNA mismatch repair protein Mlh1", "aln": "--MAFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTNIQVVVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQTFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLQAPPKPCAGNQGTLITVEDLFYNIITRRKALKNPSEEYGKILEVVGRYSIHNSGISFSVKKQGETVSDVRTLPNATTVDNIRSIFGNAVSRELIEVGCE--DKTLAFKMNGYISNANYSVKKCIF-LLFINHRLVESAALRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILQRVQQHIESKLLGSNSSRMYFTQTLLPGLAG------PSGEAARPTTGVASSSTSGSGDKVYAYQMVRTDSREQKLDAFLQPVSSLGPSQPQDPAPVRGARTEGSPERATREDEEMLALPAPAEAAAESENLERESLMETSDAAQKAAPTSSPGSSRKRHREDSDVEMVENASGKEMTAACYPRRRIINLTSVLSLQEEISERCHETLREMLRNHSFVGCVNPQW--ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEDDGPKEGLAEYIVEFLKKKAEMLADYFSVEIDEEGN--------LIGLPLLIDSYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYS--IRKQYILEESTLSGQQSDMPGSTSKPWKWTVEHIIYKAFRSHLLPPKHFTEDGNVLQLANLPDLYKVFERC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40692-1", "uniprot_id": "MLH1_HUMAN", "id": "P40692-1", "name": "DNA mismatch repair protein Mlh1", "aln": "--MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCE--DKTLAFKMNGYISNANYSVKKCIF-LLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLPGLAG------PSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQA--IVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSS--NPRKRHREDSDVEMVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQW--ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGN--------LIGLPLLIDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYS--IRKQYISEESTLSGQQSEVPGSIPNSWKWTVEHIVYKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13AAI6-1", "uniprot_id": "A0AB13AAI6_DANRE", "id": "A0AB13AAI6-1", "name": "DNA mismatch repair protein MLH1", "aln": "-----MAGVIRRLDETVVNRIAAGEIIQRPANAIKEMMENCLDAKSTNIQITVKEGGLKLILIQDNGTGIRKDDMEIVCERFTTSKLQSFEDLSSIATYGFRGEALASISHVAHVTITTKTADAKCAYRANYCDGKLKSPPKPCAGNQGTLISVEDLFYNVSTRRKALKSPSEEYSRIVEVVSRYAIHNSGKSFSVKKQGEMVADVKTLPNASVLDNIRVVFGVAVSRELIEVECE--DQKFAFKVKGYISNANYSVKKCIL-ILFINHRLVESSALKKAIETVYTAYLPKNTHPFLYLSLEIAPQNIDVNVHPTKHEVHFLHEDSIIESIQKHIESKLLGSNSSRTYFTQTLLPGLS------------ASASVAKASSSSADSQERVYAHQMVRTDSKAQKLDAFLQPSASSSSTAAQR-------KTEKTSSTSTAVQDLVELDDAELLTAADVEPCGGK------DPQTDAQPPGDEAPPRKRP----HVEEVKED----LTAASLPRRRIVKLTSIKELRDQIELQTHKGLQELLQNHSFVGSVSPQW--TLVQHQTKLYLLNTTKLSQELFYQILVYDFGNFGVLRLSNPAPLYDLAMLALDSEESGWTEEDGPKEGLAQYIVDFLKQKAEMLEEYFSLEIDAEGN--------LTGLPMLLDNYTPAMEGLPMFILRLATEVNWDKEKECFREFSVECSHFYS--IRKSYTLEADADEPQDAEMS------WQWKVEHVLFKALRSLFSPAKHLSEDGSVLQIASLPDLYKVFERC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7C1-1", "uniprot_id": "A1Z7C1_DROME", "id": "A1Z7C1-1", "name": "", "aln": "MAEYLQPGVIRKLDEVVVNRIAAGEIIQRPANALKELLENSLDAQSTHIQVQVKAGGLKLLQIQDNGTGIRREDLAIVCERFTTSKLTRFEDLSQIATFGFRGEALASISHVAHLSIQTKTAKEKCGYKATYADGKLQGQPKPCAGNQGTIICIEDLFYNMPQRRQALRSPAEEFQRLSEVLARYAVHNPRVGFTLRKQGDAQPALRTPVASSRSENIRIIYGAAISKELLEFSHR--DEVYKFEAECLITQVNYSAKKCQM-LLFINQRLVESTALRTSVDSIYATYLPRGHHPFVYMSLTLPPQNLDVNVHPTKHEVHFLYQEEIVDSIKQQVEARLLGSNATRTFYKQLRLPGAP-----------------DLDETQLADKTQRIYPKEMVRTDSTEQKLDKFLAPLVKSDSGVSSS-----------SSQEASRLPEESFRVTAAKKS------------------------------------------------------------REVRLSSVLDMRKRVERQCSVQLRSTLKNLVYVGCVDERR--ALFQHETRLYMCNTRSFSEELFYQRMIYEFQNCSEITISPPLPLKELLILSLESEAAGWTPEDGDKAELADGAADILLKKAPIMREYFGLRISEDGM--------LESLPSLLHQHRPCVAHLPVYLLRLATEVDWEQETRCFETFCRETARFY-----AQLDWREGATAGFS-----------RWTMEHVLFPAFKKYLLPPPRIKD--QIYELTNLPTLYKVFERC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38920-1", "uniprot_id": "MLH1_YEAST", "id": "P38920-1", "name": "DNA mismatch repair protein MLH1", "aln": "-----MSLRIKALDASVVNKIAAGEIIISPVNALKEMMENSIDANATMIDILVKEGGIKVLQITDNGSGINKADLPILCERFTTSKLQKFEDLSQIQTYGFRGEALASISHVARVTVTTKVKEDRCAWRVSYAEGKMLESPKPVAGKDGTTILVEDLFFNIPSRLRALRSHNDEYSKILDVVGRYAIHSKDIGFSCKKFGDSNYSLSVKPSYTVQDRIRTVFNKSVASNLITFHISKVEDLNLESVDGKVCNLNFISKKSISPIFFINNRLVTCDLLRRALNSVYSNYLPKGNRPFIYLGIVIDPAAVDVNVHPTKREVRFLSQDEIIEKIANQLHAELSAIDTSRTFKASSISTNKPESLIPFNDTIESDRNRKSLRQAQVVENSYTTANSQLRKAKRQENKLVRIDASQAKITSFLSSSQQFNFEGSSTKRQLSEPKVTNVSHSQEAEKLTLNESEQPRDANTINDNDLKDQPKKKQKLGDYKVPSIADDEKNALPIS--KDGYIRVPKERVNVNLTSIKKLREKVDDSIHRELTDIFANLNYVGVVDEERRLAAIQHDLKLFLIDYGSVCYELFYQIGLTDFANFGKINLQSTNVSDDIVLYNLLSEFDELN-DDASK----EKIISKIWDMSSMLNEYYSIELVNDGLDNDLKSVKLKSLPLLLKGYIPSLVKLPFFIYRLGKEVDWEDEQECLDGILREIALLYIPDMVPKVDTSDASLSEDEKAQFINRKEHISSLLEHVLFPCIKRRFLAPRHILK--DVVEIANLPDLYKVFERC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: ** ***:*****:* *.**:**: **.:**::* *:: *: **:*:: * ***:**.: *: *:********* ****: * *:**************:::: **. . :*.::..*.:**: *** **::** * :****:*: * :**:. :*: :: :*:.**::*. .*: :* *: : . : :.** ::. ::: :*: . :. . . : : *: **. ::***:*** . *: :::::*: ***:. :**:*: : : * :********:**:** ::.*:: : :::.:.* . :::* : . .. . .:. . :: ::. :** : . . .. : * :.*:*: .::..:. * . : * :** *. . : **: :*:: : ... ***** : :* * . : : . :: : * * . :*. * : . : . : :: :*:.:.: :* * .** *:. : * : **.:: **..**:*:.* .*: : * : :* . : . :**::: .:: : .. :: . .: :::.** * ******", "identical_positions": 183, "similar_positions": 232, "identity": "23.37%" }, { "cls_id": "homologset.agr.RGD:620938", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EP64-1", "uniprot_id": "TNMD_MOUSE", "id": "Q9EP64-1", "name": "Tenomodulin", "aln": "MAKNPPENCEGCHILNAEALKSKKICKSLKICGLVFGILALTLIVLFWGSKHFWPEVSKKTYDMEHTFYSNGEKKKIYMEIDPITRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEIDENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLIAVSELQDFEEDGEDLHFPTSEKKGIDQNEQWVVPQVKVEKTRHTRQASEEDLPINDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ESC2-1", "uniprot_id": "TNMD_RAT", "id": "Q9ESC2-1", "name": "Tenomodulin", "aln": "MAKNPPENCEGCHILNAEALKSKKIRKSLKICGLVFGILALTLIVLFWGSKHFWPEVSKKTYGMEHTFYSNGEKKKISMEIDPITRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEIDENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLIAVSELQDFEEDGEDLHFPTSEKKGIDQNEQWVVPQVKVEKTRRTRQASEEDLPVNDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H2S6-1", "uniprot_id": "TNMD_HUMAN", "id": "Q9H2S6-1", "name": "Tenomodulin", "aln": "MAKNPPENCEDCHILNAEAFKSKKICKSLKICGLVFGILALTLIVLFWGSKHFWPEVPKKAYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEIDENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLISVSELQDFEEEGEDLHFPANEKKGIEQNEQWVVPQVKVEKTRHARQASEEELPINDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********.********:***** *******************************.**:*.************** *****:***********************************************************************************************************:*********:*******:.*****:****************::******:**:************************************************************************", "identical_positions": 300, "similar_positions": 15, "identity": "94.64%" }, { "cls_id": "homologset.agr.RGD:620939", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Y1-1", "uniprot_id": "TIM_RAT", "id": "Q9Z2Y1-1", "name": "Protein timeless homolog", "aln": "--------------MDLYMMNCELLATCSALG------YLEGGTYHKEPDCLESVKDLIRYLRHEDETR---DVRQQLGAAQILQSDLLPILTQHRQDKPLFDAVIR-----------------------LMVNLTQPALLCFGS-VPKDPTVRHHFLQVLTYLQAYKEAFASEKAFGVLSETLYELLQLGWEDRQEEDNLLIERILLLVRNILHVPAN------------------LEQEKRIDDDASIHDRLLWAIHLSGMDDLLLFLSSSS----AEQQWSLHVLEIISLMFRDQKPEQLAGVGQGRLAQERSTDLAE--------------LEVLRQREVAEKRARALQRGNRHSRFGGSYVVQG-----LKSIGE----RDVVFHKGLHNLQNYSSDLGKQPRRVPKRRQAAQELSVHRRSVLNVR----LFLRDFCSEFLENCYNPLMGAVKDHLLR--EKAQQHDETYYMWAMAFFMAFNRAAAFRPGFVSETLSIRTFHFVEQNLTNYYEMMLTDRKEAASWARRMHLALKAYQELLATVNEMDMCPDD-AVRESSRIIKNNIFYMMEYRELFLALFRKFDERYHPRSFLCDLVETTHLFLKMLERFCRSRGNLMVQNKRKKR-KKKKKAQEQGVAFS---RSPEELQAMWSALAERLLQCAQEPELSVDS--IIPFDAASEVPVEEQRVEAMVRIQDCLVAGQAPQALALLRSAREVWPEGNVFGSPVISPGEEMQLLKQILSATLPRQQEPVEGDAEEEDEEEEEEEEEELQVVQVSEKE-------FKFLDYLKRFACSTIVRAYVLLLRSYRQNSAHTNHCIAKMLHRLAHDLGMEALLFQLSLFCLFNQLLSDPAAAAYKELVTFAKYILGKFFALAAVNQKAFVELLFWKNTSVVREMTQGYGSLDSGSCSHRAPVWSSEEEAQLQELYLAHKDVE--GQDVVETILAHLKAVPRTRKQVIHHLVRMGLADSVKDFQ-RKGTQ--IVLWTEDQELELQRLFEEFQDSDDVLGHIMKNITAKRSRARVVDKLLALGLVSERRQLHKKRR---KKLAPSCMQNGEESQRDAWQEDPEEEEEKEGLPESEGEENEEDLLAGQVQGSSSLSAENLRQSLCQDGLSAPLLWLQSSLIRAADDREEDG-CSQAIPLVPLTEENEEAMENKQFQHLLRKLGIRAPCSGQETFWRIPAKLSSTQLRRVAASLSERENKEEREEEPEPNPGVPGEQSPSE----EHQVRAPRALLSARKRKAGLVFPKEE-ATGEEEWKSVPKKQ-------------------------------------------------------------------------------------QLLDSDEED----TDDERGGQAAVSGTLRIHKEKRFLVEDEDEDY----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1X4-1", "uniprot_id": "TIM_MOUSE", "id": "Q9R1X4-1", "name": "Protein timeless homolog", "aln": "--------------MDLYMMNCELLATCSALG------YLEGGTYHKEPDCLESVKDLIRYLRHEDETR---DVRQQLGAAQILQSDLLPILTQHRQDKPLFDAVIR-----------------------LMVNLTQPALLCFGS-VPKDSSVRHHFLQVLTYLQAYKEAFASEKAFGVLSETLYELLQLGWEDRQEEDNLLIERILLLVRNILHVPAN------------------LEQEKSIDDDASIHDRLLWAIHLSGMDDLLLFLSSSS----AEQQWSLHVLEIISLMFRDQTPEQLAGVGQGRLAQERSTDVAE--------------LEVLRQREMAEKRARALQRGNRHSRFGGSYIVQG-----LKSIGE----KDVVFHKGLHNLQNYSSDLGKQPRRVPKRRQAAQELSVHRRSVLNVR----LFLRDFCSEFLENCYNPLMGAVKDHLLR--ERAQQHDETYYMWAMAFFMAFNRAATFRPGLVSETLSIRTFHFVEQNLTNYYEMMLTDRKEAASWARRMHLALKAYQELLATVNEMDMCPDE-AVRESSRIIKNNIFYMMEYRELFLALFRKFDERYHPRSFLRDLVETTHLFLKMLERFCRSRGNLMVQNKRKKR-KKKKKVQDQGVAFS---QSPGELEAMWPALAEQLLQCAQDPELSVDP--VVPFDAASEVPVEEQRVEAMVRIQDCLTAGQAPQALALLRSAREVWPEGNAFGSPVISPGEEMQLLKQILSTPLPRQQEPEEGDAEEE---EEEEEEEELQVVQVSEKE-------FNFLEYLKRFASSTIVRAYVLLLRSYRQNSAHTNHCIAKMLHRLAHGLGMEALLFQLSLFCLFNRLLSDPAAAAYKELVTFAKYIIGKFFALAAVNQKAFVELLFWKNTAVVREMTQGYGSLDSGSSSHRAPLWSPEEEAQLQELYLAHKDVE--GQDVVETILAHLKVVPRTRKQVIHHLVRMGLADSVKEFQKRKGTQ--IVLWTEDQELELQRLFEEFRDSDDVLGQIMKNITAKRSRARVVDKLLALGLVSERRQLYKKRR---KKLAPSCMQNGEKSPRDPWQEDPEEEDEHLPEDESEDEESEEGLPSGQGQGSSSLSAENLGESLRQEGLSAPLLWLQSSLIRAANDREEDG-CSQAIPLVPLTEENEEAMENEQFQHLLRKLGIRPPSSGQETFWRIPAKLSSTQLRRVAASLSQQENEEEREEEPEP--GVPGEQGPSE----EHRTEALRALLSARKRKAGLGPTEEE-ATGEEEWNSAPKKR-------------------------------------------------------------------------------------QLLDSDEE------EDDEGRRQAVSGTPRVHRKKRFQIEDEDD------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNS1-1", "uniprot_id": "TIM_HUMAN", "id": "Q9UNS1-1", "name": "Protein timeless homolog", "aln": "--------------MDLHMMNCELLATCSALG------YLEGDTYHKEPDCLESVKDLIRYLRHEDETR---DVRQQLGAAQILQSDLLPILTQHHQDKPLFDAVIR-----------------------LMVNLTQPALLCFGN-LPKEPSFRHHFLQVLTYLQAYKEAFASEKAFGVLSETLYELLQLGWEERQEEDNLLIERILLLVRNILHVPAD------------------LDQEKKIDDDASAHDQLLWAIHLSGLDDLLLFLASSS----AEEQWSLHVLEIVSLMFRDQNPEQLAGVGQGRLAQERSADFAE--------------LEVLRQREMAEKKTRALQRGNRHSRFGGSYIVQG-----LKSIGE----RDLIFHKGLHNLRNYSSDLGKQPKKVPKRRQAARELSIQRRSALNVR----LFLRDFCSEFLENCYNRLMGSVKDHLLR--EKAQQHDETYYMWALAFFMAFNRAASFRPGLVSETLSVRTFHFIEQNLTNYYEMMLTDRKEAASWARRMHLALKAYQELLATVNEMDISPDE-AVRESSRIIKNNIFYVMEYRELFLALFRKFDERCQPRSFLRDLVETTHLFLKMLERFCRSRGNLVVQNKQKKRRKKKKKVLDQAIVSGNVPSSPEEVEAVWPALAEQLQCCAQNSELSMDS--VVPFDAASEVPVEEQRAEAMVRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQILSAPLPRQQGPEERGAEEE-EEEEEEEEEELQVVQVSEKE-------FNFLDYLKRFACSTVVRAYVLLLRSYQQNSAHTNHCIVKMLHRLAHDLKMEALLFQLSVFCLFNRLLSDPAAGAYKELVTFAKYILGKFFALAAVNQKAFVELLFWKNTAVVREMTEGYGSLDDRSSSRRAPTWSPEEEAHLRELYLANKDVE--GQDVVEAILAHLNTVPRTRKQIIHHLVQMGLADSVKDFQ-RKGTH--IVLWTGDQELELQRLFEEFRDSDDVLGHIMKNITAKRSRARIVDKLLALGLVAERRELYKKRQ---KKLASSILPNGAESLKDFCQEDLEEE-ENLPEEDSEEEE-EGGSEAEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQNCLIRAADDREEDG-CSQAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQETFWRIPAKLSPTQLRRAAASLSQPEEEQKLQPELQP--KVPGEQGSDEEHCKEHRAQALRALLLAHKKKAGLASPEEEDAVGKEPLKAAPKKR-------------------------------------------------------------------------------------QLLDSDEEQ----EEDEGRNRAPELGAPGIQKKKRYQIEDDEDD-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8INH7-1", "uniprot_id": "Q8INH7_DROME", "id": "Q8INH7-1", "name": "", "aln": "----------------MSILLADIDATCAALG------YSDGQKYQAEPDAAEGLKHLIWILRRDLDNH---EYRRHLGRSKVLQTDLVYMLPDYVHHEELSDLLIR-----------------------LLVILTNPTLLLYREGAPKDNHGRKVFMELIDILQGYKAAFAKDKVWSALFEKLKQALEIAFAIRSEEQNLLIERILVLVRNVLQVPAN------------------PEAECRADNDASLHDQVIWALHQTGMLDLVLFVISSP----DEEQFHLHGLEIVCLLFREQSAESLADASLQRSLSEKQRDQQE--------------LLAARRRERARRQARPPP--GRHSRFGGTYVIRN-----MKSVSD----RDVICHQALERVSSIDFDREKQQQKRS-HRHIQEEAQVTRRSAFTVR----LCLREYCIEVLRSAYNTLVRQVRRVLERN-AGSSSHDDSYLLWAIRFFMEFNRLSGLQLQLVSESLSVQCFHWVLTRMQHDMDMIVSDKKQARLWAKRLHVALLTFRELLQSLLALQKLKDDNNARALFDMLLNNVCYVLEYRETVLHLLMNYNEAHSTKVFLRDVVETANVFIKMMERFCQDSVVVQDKKRGRGASRKKKQAATKSKPPAAPQPTEEELSSKWAELATEVCSLLSTELEMPEDEQPLPFDAASEKSIDDQREDCMIRINKLLRSEKLDQAIALLRAAREVWPENEVFGAISAAPEDELLLLREIFMSNITTVESEDKENEKDQKQDEYEDEDDDLDNEEYEEQDNGLTEKTFKFDDFARRLLNPKIVRACTLVLSDWADIPTRSLKAAVTILHRIAYGCKCAGMLFQAKLFRIFQQVFSVERDVHQEELRRLAIFVVRKFVEVAPTNPKIYAELLFYKGIREANELESGYCDAYEAGTKG---AWTEEQESELRFLFEENQRNPETDKDVIDWILDNLVDKTRNRRTVLKKLKELGLLFKAPTKRSTKSAQSGKNVWQPEEDDELRSLYDQHRIEPDCLERLVNEFAERRSKQQIIKRMLQIHLIADKSEILPAKKGRGKDKPKKDVEMEGEGDEFDFAEEPMFEDQGYKKPKSKPKKVQKRQMVRTPLDVGTIR--ALIGQVDSEKYQSAIEWLQECLQDASEDTEEAVEDDDGVPLLPLMENQKNAMEDGDFQKVLVALGMQPPISGMEAYWRIPIYLNSADLILRSKILAGEEVDAEPEDEAADDEDGEEAEESDEEEDFLEKHSRQRKENIATQQQRKLDSLMFNQSDDETEQRAPPKAKDKPKASEKKAKRKVKGKAKESKDCNDDGTDKAELEKPNTDDLFNQLRAKRATKIKLSDMALNESTNAAQEADDDAFNFNSEDYRARLLELEDEEQNSKDADENGGDKENITNKSLQRARRVNVIDSDSDNDDDGALPADKTNKRPRSDDDGDSGHMDANAEEDSDEEANFLARKKPAKVDGEPAKRRRLAIIDDDDEDDF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53840-1", "uniprot_id": "TOF1_YEAST", "id": "P53840-1", "name": "Topoisomerase 1-associated factor 1", "aln": "MSADLQQGTTNAADFSLTVLRARIALLATAIGGPDYTSQIDPPPYKLGDDCLACLKDLKRWFKLVDDQQKRWDVAMAVAEYRILTDDLLPILIDWENKCSLAAKLAKNNPDHEEFRNKAYYDKIALNCLQLLVLMTWPLIVTEQS-SSNQITLYGELKKHQLVYKKTILSMESGKVLRAAIRLALDVIKIDRLSRTPRDNMVLKLVLNFFRNVIAIEPGEFTINTKKSMPKKGITSIDTLPPNVSMDDISLNTVISSFHKNKVFGFLLTLTSSLSKEFDQDFINIPLLEIMFYFTKDVNQELLFPRQFETGTHSKVVNKNESSSANNIVTSAGFELSKLLQKEHQMRKNVIKHTSARHSRFGGLLSIQTPDKTRLTVSGSQALVDEKIALQKLDDSKKWNKRIIKKHQSVAAEGLPNSLLNSQTGKAIFFTESNGKHFKEFINNFIDSGFNILLHSVTNYFTTEQDRMVTLEQVEYLLFFAWFVKYQLLR----SKIDNSADIKQVSEALKEVTFILVSSLLRSAYDLKNWTVTHAGMIAFNELLNLVSRTKAAQEE----DSTDIEFIVSRLFSDERIQLLSNLPKIGSKYS-LQFMKSCIELTHSVLKVLEQYSDDKTLVIEGKSRRQK----KFNISEGDITKLIEEENVDRDEALDILTSSLRSIEVN------------FQKVQANYMTEPVIETYINFLERFRELEDDSIKKVFS----------FFHRVFVQAKEQALLFRFDLIILLREMLSPDGLDRMSRSRKYVSQFSDYFLARLKKRLK--------KSPAWFVGLLFPPLHNSEVGFYQRYGEYNVLNNESMYAAPASQFKPIPDEEALPPSILLDMKYGVLVS------TLLDDGKTELLDQLLKHITHTLDIFKSWLTVNVNAGKETVNPPNEYFTLTGVLNNDPIFKDKDYRALLLLIGYSIPRK------INEPCFLPGTVEVSDLTVSCELVKKYLSTPFETPNGLPSSS--YLLRVRSEKDSFSHNEQDGWEGDDDYDYNDPYIVPD-------DQILSKSDAAYFKDLDNNAS---DKLKGTKFSKGIARSKKKDKRKRRKGEAKTNLPMFGDQDDERPQTVRERHG--VFSKEFISDSEDDEDLMNPIFFENETYMRWLLDKNNGQLTEDRYIQFAKFAAERMNNGGVVTGDYTSLFGGSIPSIESIRATESSSFAPDKSLISLASHVASEMSIFDVNNNNNN-------QLSDD-----DVNSESRNSLGSSQPSNSQNMFQSEVYSRKESTKRSLEAS----------------------------------------------------------------------------------------------------AADESDEDEEAIRLFGKKSRVVLSQGDSDD----------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . : .:*:* : *: *. :*.* :: : : : :. ::* **: :* : :. * : : *:* :* * :: . .:: : : : :: . *. . . : ::: * .:*:::: :* :.**:: : .. . * : :: ::* . : .::* : ** :: : ***: : :: . * * .: : * * ::* :: ******* :: :. .. : : : *. . . *: : . . . ..: . :::: :.: . :* *: * : :: : : :*: :: :.:: .:: . .: : * .: ::.*** : . :: : . : * .* : : .. *: . :* :: .:*::*::. . : : : * :. : . *: : *: .. : : : :.: . : : . :: * . :: *:: : : . .. .: .: : .. . : : : . : .: . . : : . . .. * :: : :: * :: ::. . . . : . * : . : . :. :: * * :: . : .* . * . .: : .:. .: :: * :. .::* : :: .. . . . .. :. : . : : . .: .: : :. * :: .: .. :. . . :* * . . .* : :: . : : : ..: . * : : . : : . : . : * : : :. ", "identical_positions": 77, "similar_positions": 336, "identity": "5.17%" }, { "cls_id": "homologset.agr.RGD:620940", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AM29-1", "uniprot_id": "AF9_MOUSE", "id": "A2AM29-1", "name": "Protein AF-9", "aln": "MASSCAVQVKLELGHRAQVR--KKPTVEGFTHDWMVFVRGPEHSN---IQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGG-------------------------------------------------------------DPNR-----------------------SIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---------------SSSSSSSSSTSFSKPHKLMKEHKEKPSKD---------------------------------------------------------------------SREHKSAFKEPSRDHNKSSKDSSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKADSNLLTVTSGQQDKKAPSKRPPAS----------------DSEELSAKKRKKSSSEALFKSFSSAPPLILTCS-ADKKQIKDKSHVKMG------------KVKIESETSEKKKSMLPPFDDIVDPNDSDVEENMSSKSDSEQPSPASSSSSSSS----------------------------------------------------------------------SFTPSQTRQ-QGPLRSIMKDLHSD------------------------------------DNEEESDEAEDNDNDSEMERPVNRGGS-RSRRVSLSDGSDSESSSASSPLHHEP---------------------------------------------PPPLLKTNNNQILEVKSPIKQSKSDKQIKNGE----------------CDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZRB6-1", "uniprot_id": "A0A8I5ZRB6_RAT", "id": "A0A8I5ZRB6-1", "name": "", "aln": "MASSCAVQVKLELGHRAQVR--KKPTVEGFTHDWMVFVRGPEHSN---IQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGG-------------------------------------------------------------DPNR-----------------------SIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---------------SSSSSSSSSTSFSKPHKLMKEHKEKPSKD---------------------------------------------------------------------SREHKSAFKEPSRDHNKSSKDSSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKADSNLLTVTSAQQDKKAPSKRPPVS----------------DSEELSAKKRKKSSSEALFKSFSSAPPLILTCS-ADKKQIKDKSHVKMG------------KVKIESETSEKKKSTLPPFDDIVDPNDSDVEENMSSKSDSEQPSPASSSSSSSS----------------------------------------------------------------------SFTPSQTRQ-QGPLRSIMKDLHSD------------------------------------DNEEESDEAEDNDNDSEMERPVNRGGS-RSRRVSLSDGSDSESSSASSPLHHEP---------------------------------------------PPPLLKTNNNQILEVKSPIKQSKSDKQIKNGE----------------CDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42568-1", "uniprot_id": "AF9_HUMAN", "id": "P42568-1", "name": "Protein AF-9", "aln": "MASSCAVQVKLELGHRAQVR--KKPTVEGFTHDWMVFVRGPEHSN---IQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGG-------------------------------------------------------------DPNR-----------------------SIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---------------SSSSSSSSSTSFSKPHKLMKEHKEKPSKD---------------------------------------------------------------------SREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQ-DKKAPSKRPPIS----------------DSEELSAKKRKKSSSEALFKSFSSAPPLILTCS-ADKKQIKDKSHVKMG------------KVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSS----------------------------------------------------------------------SFTPSQTRQ-QGPLRSIMKDLHSD------------------------------------DNEEESDEVEDNDNDSEMERPVNRGGS-RSRRVSLSDGSDSESSSASSPLHHEP---------------------------------------------PPPLLKTNNNQILEVKSPIKQSKSDKQIKNGE----------------CDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BAV5-1", "uniprot_id": "A0A8M3BAV5_DANRE", "id": "A0A8M3BAV5-1", "name": "", "aln": "MASSGAVQVKLELGHRAQVR--KKPTVEGFTHDWMVFVRGPEHSN---IQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEEFRRKLLKAGGQ-----------------------------------------------------------RDPHKRSSEDSKVMVMQEGSTSLFGPHLKLPTLPSSSLTLTFSDAKKSKSFPGSKDGSKSSSALT---------------TTNNISSSSLKLHKPPKDHKDHKDKPSKD---------------------------------------------------------------------SKESKSAFRDFSKDSGKLSKDS-KKPKENQPIQEDRPIPQMGFKEPKSTSKEQRS-SELSFSSLGQ------SKRRPVL----------------DNEGHVTKKRKSSFSESSQKQQACPALLQQQHHHSDKKVLKDKPQIRHN------------RLQNSELSEKKKLQALPPFQDVLDPNDSDMDDNTFTRSDSDQPSPASSSSSSSS----------------------------------------------------------------------GFGRGHKRQVLGPLRSVIPDLHSD------------------------------------ENEEDSEEDDDNDMDSDLERPVHTQMTHRHRRVSLSDGSESENSSGSSPLPHND---------------------------------------------PPPLLKNSSNQ-IEVKGPIKQAKMDK-NKNID----------------CDKAYLDELVELHRRLMALRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETTGSS-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG69-1", "uniprot_id": "A0A0B4KG69_DROME", "id": "A0A0B4KG69-1", "name": "", "aln": "----MAVKVQFEIGHTSKLRSKKTPHPQAFTHDWEIYVQGVNKAD---ISAFVEKVVFVLHESFPKPKRVVKEPPYAIQESGYAGFLLPVEIYFRNRDEPKRIVYQYDLVLQSTG-PPQHHVEVKTHIFEAPSEEFRTKLMRGGGVPVFGANIGAGSLARTLSPSVGSGETAHSNEMSGVKAKGVPGTISMNSDLNTGKKHKSRSEDPGKSNAFSALFGPPITKTSVTANNMAQVPVSKHSPEAKSAAVGGKGVFHEGREKASKDRDKSSGGDKPREKDKKDRHGRDKDRKSSKSGDGKHERDKEKSKKDKSRDKEREREQGSGNTTSANALTVATSVGTAGGLVKHTASPKPGKPNEMGAPSPKKTANDSAAGAVAPTSRSKERDEHKSVKSESKDKERSSSKKSKKDKKDKDKQRDESKDKRMPKDERPGQSDSPASGNLQSAHLQQQSQVASTGKATPTSVGSNSSSSMVSNIGKQKEEATGKHSEKAAESKGDKSTSNGNATDTKKSHKHKKKEKSKDKEKERNDRDKDKDKERDKDKLKEREKDKQHVTGSEKSSTVDPSPKLEGASPATEGGAPDKTPVSASASSGSKKEKHKKSKEKSSGKDEKRQREAVDKQADTKHTGKSQQSQSGQSKTPSNLDLSDMDSAQSAPDLAATNALAAAAAATLQHSDSSNSSFPDLPARSSSQQKPTKGNTGSGKETKSTVKEHKGKSKQNDKTLEKNTDKTEKPDKTPDPKVDKSEKSEKEDKKRNRRSSQSSNSGSGAGVTGAFIEPPVKASKKEQGKAAGEKSKSPSLRPPRETNSTGTGGGTPNAGAGFLAPPSSSPSNNHSAAVAASLNNNNNNNNNNTNSNSSHSPGEMTTPGQLQLPTEYLSELQELHHKIMTLQDNEELQHVVEMIAATGCYEITHKTFDFDLCKLDRGTVQRLQEFLATSVSXHSLTSATGPALYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35189-1", "uniprot_id": "TAF14_YEAST", "id": "P35189-1", "name": "Transcription initiation factor TFIID subunit 14", "aln": "--MVATVKRTIRIKTQQHILPEVPPVENFPVRQWSIEIVLLDDEGKEIPATIFDKVIYHLHPTFANPNRTFTDPPFRIEEQGWGGFPLDISVFLLEKAGERKIPHDLNFLQESYEVEHVIQIPLNKPLLT-------EELAKSGS---------------------------------------------------------------------------------------------TEETTANTGTIGKRRTTTNTTAEPKAKRAKTG----------------SASTVKGSVDLEKLAFGLTKLNE----------------------------------------------------------------------------DDLVGVVQMVTDNKTPEMNVTNNVEEGEFIIDLYSLPEGLLKSLWDYVKKNTE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: :.: :: * : .::* : : :. . :.:**:: ** :*..*:*. .:**: ::*.*:.** * :.::: :: ::: .: ::. . :: :. : :* :.*. .. : : : . . . . . ... * . :. : .. . * . . :: ::.: : *. .. ", "identical_positions": 22, "similar_positions": 91, "identity": "2.31%" }, { "cls_id": "homologset.agr.RGD:620942", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63036-1", "uniprot_id": "DNJA1_RAT", "id": "P63036-1", "name": "DnaJ homolog subfamily A member 1", "aln": "MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKN-PNE--GEKFKQISQAYEVLADSKKRELYDKGG---------EQAIK----EGGAGGG-----------FGSPMDIFDMFFGG--------------------------------------------GGRMQR-ERRGKNVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGD--------QEPGLEPGDIIIVLDQKDHAVFTRRGED--LFMCMDIQLVEALCGFQKPIS-TLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYE--KGRLIIEFKVNFPENGFLSPDKLSLLEKLLPE--RKEVEET-----------------DEMDQVELVDFDPNQE---------------RRRHYNGEAYEDDEHHPRGG---VQCQTS--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63037-1", "uniprot_id": "DNJA1_MOUSE", "id": "P63037-1", "name": "DnaJ homolog subfamily A member 1", "aln": "MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKN-PNE--GEKFKQISQAYEVLADSKKRELYDKGG---------EQAIK----EGGAGGG-----------FGSPMDIFDMFFGG--------------------------------------------GGRMQR-ERRGKNVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGD--------QEPGLEPGDIIIVLDQKDHAVFTRRGED--LFMCMDIQLVEALCGFQKPIS-TLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYE--KGRLIIEFKVNFPENGFLSPDKLSLLEKLLPE--RKEVEET-----------------DEMDQVELVDFDPNQE---------------RRRHYNGEAYEDDEHHPRGG---VQCQTS--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31689-1", "uniprot_id": "DNJA1_HUMAN", "id": "P31689-1", "name": "DnaJ homolog subfamily A member 1", "aln": "MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKN-PNE--GEKFKQISQAYEVLSDAKKRELYDKGG---------EQAIK----EGGAGGG-----------FGSPMDIFDMFFGG--------------------------------------------GGRMQR-ERRGKNVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGD--------QEPGLEPGDIIIVLDQKDHAVFTRRGED--LFMCMDIQLVEALCGFQKPIS-TLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYE--KGRLIIEFKVNFPENGFLSPDKLSLLEKLLPE--RKEVEET-----------------DEMDQVELVDFDPNQE---------------RRRHYNGEAYEDDEHHPRGG---VQCQTS--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFV9-1", "uniprot_id": "Q9VFV9_DROME", "id": "Q9VFV9-1", "name": "", "aln": "MVKETGYYDILGVKPNATPDELKKAYRKLALKYHPDKN-PNE--GEKFKAISQAYEVLSDADKRQVYDEGG---------EAAIK----KGGADSGD----------FRNPMDFFEKFFGAGFGGS---------------------------------------GGGRRR-ERRGKDVVHQMSVQLEELYNGATRKLQLQKNVICDKCEGRGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGETIQEKDRCKNCSGRKTVRERKVLEVHIEKGMRDGQKIVFTGEGD--------HEPESQPGDIIILLDEKEHSTFAHAGQD--LMMKMPLQLVEALCGFQRIVK-TLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPME--KGTLIIQFEVIFPE--VINPSVVPTLKQCLPP--APEVDIP-----------------IDAEQTVLEDFDPKQ----------------RRQQHQRMAYDEDDGGYQDGPRVQQCTSS--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25491-1", "uniprot_id": "MAS5_YEAST", "id": "P25491-1", "name": "Mitochondrial protein import protein MAS5", "aln": "MVKETKFYDILGVPVTATDVEIKKAYRKCALKYHPDKN-PSEEAAEKFKEASAAYEILSDPEKRDIYDQFG---------EDGLSGAGGAGGFPGGG----------FGFGDDIFSQFFGAG-------------------------------------------GAQRPRGPQRGKDIKHEISASLEELYKGRTAKLALNKQILCKECEGRGGKKGAVKKCTSCNGQGIKFVTRQMGP-MIQRFQTECDVCHGTGDIIDPKDRCKSCNGKKVENERKILEVHVEPGMKDGQRIVFKGEAD--------QAPDVIPGDVVFIVSERPHKSFKRDGDD--LVYEAEIDLLTAIAGGEFALE-HVSGDWLKVGIVPGEVIAPGMRKVIEGKGMPIPKYGG---YGNLIIKFTIKFPENHFTSEENLKKLEEILPPRIVPAIPKK-----------------ATVDECVLADFDPAKY---------------NRTRASRGGANYDSDEEEQGGEGVQCASQ--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53940-1", "uniprot_id": "APJ1_YEAST", "id": "P53940-1", "name": "J domain-containing protein APJ1", "aln": "MQQNTSLYDSLNVTAAASTSEIKKAYRNAALKYHPDKNNHTEESKRKFQEICQAYEILKDNRLRALYDQYGTTDEVLIQEQQAQAQRQQAGPFSSSSNFDTEAMSFPDLSPGDLFAQFFNSSATPSSNGSKSSFNFSFNNSSTPSFSFVNGSGVNNLYSSSAKYNSNDEDHHLDRGPDIKHNLKCTLKELYMGKTAKLGLNRTRICSVCDGHGGLKK--CTCKTCKGQGIQTQTRRMGP-LVQSWSQTCADCGGAGVFVKNKDICQQCQGLGFIKERKILQVTVQPGSCHNQLIVLTGEGDEVISTKGGGHEKVIPGDVVITILRLKDPNFQVINYSNLICKKCKIDFMTSLCGGVVYIEGHPSGKLIKLDIIPGEILKPGCFKTVEDMGMPKFINGVRSGFGHLYVKFDVTYPER--LEPENAKKIQNILANDKYIKAERSTMETADSDCYCDLEKSYDSVEEHVLSSFEAPNLNNEVIEDDDLGDLINERDSRKRNNRRFDESNINNNNETKRNKYSSPVSGFYDHDINGY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::* ** *.* *: *:*****: ********* .* .**: . ***:* * * :**: * : . * .. *:* **.. . : ** :: *::. *::** * * ** *:: :*. *:*:** * * *.* *:: :::.* ::* . * * * * :. ** *:.*.* .*:*:*:* :: * ..* *.: **.* ***::: : . . * . . : :::: ::.* :. .. : : **::: * : *** * * ::* : :** . . ::: *. :: * .*:. : .* . *. . . : . ", "identical_positions": 102, "similar_positions": 110, "identity": "19.14%" }, { "cls_id": "homologset.agr.RGD:620943", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYU4-1", "uniprot_id": "CRYM_RAT", "id": "Q9QYU4-1", "name": "Ketimine reductase mu-crystallin", "aln": "MRRAPAFLSADEVQDHLR--SSSLLIPPLEAALANFSKGPDGGVMQPVRTVVPVAKHRGFLGVMPAYSAAEDALTTKLVTFYEGHSNN-AVPSHQASVLLFDPSNGSLLAVMDGNVITAKRTAAVSAIAT---------KFLKPP-GSDVLCILGAGVQAYSHYEIFTEQFS-----------------FKEVRMWNRTRENAEKFASSVQGDVR------VCSSVQEAVTGADVIITVTMATEPILFG--------EWVKPGAHINAVGASRPDWRELDDELMK-------QAVLYVDSREAALKESGDVLLS--------GADIFAELGEVVSGAKPAYCEKTT-VFKSLGMAVEDLVAAKLVYDSWSSGK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54983-1", "uniprot_id": "CRYM_MOUSE", "id": "O54983-1", "name": "Ketimine reductase mu-crystallin", "aln": "MKRAPAFLSAEEVQDHLR--SSSLLIPPLEAALANFSKGPDGGVMQPVRTVVPVAKHRGFLGVMPAYSAAEDALTTKLVTFYEGHSNT-AVPSHQASVLLFDPSNGSLLAVMDGNVITAKRTAAVSAIAT---------KLLKPP-GSDVLCILGAGVQAYSHYEIFTEQFS-----------------FKEVRMWNRTRENAEKFASTVQGDVR------VCSSVQEAVTGADVIITVTMATEPILFG--------EWVKPGAHINAVGASRPDWRELDDELMR-------QAVLYVDSREAALKESGDVLLS--------GADIFAELGEVISGAKPAHCEKTT-VFKSLGMAVEDLVAAKLVYDSWSSGK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14894-1", "uniprot_id": "CRYM_HUMAN", "id": "Q14894-1", "name": "Ketimine reductase mu-crystallin", "aln": "MSRVPAFLSAAEVEEHLR--SSSLLIPPLETALANFSSGPEGGVMQPVRTVVPVTKHRGYLGVMPAYSAAEDALTTKLVTFYEDRGITSVVPSHQATVLLFEPSNGTLLAVMDGNVITAKRTAAVSAIAT---------KFLKPP-SSEVLCILGAGVQAYSHYEIFTEQFS-----------------FKEVRIWNRTKENAEKFADTVQGEVR------VCSSVQEAVAGADVIITVTLATEPILFG--------EWVKPGAHINAVGASRPDWRELDDELMK-------EAVLYVDSQEAALKESGDVLLS--------GAEIFAELGEVIKGVKPAHCEKTT-VFKSLGMAVEDTVAAKLIYDSWSSGK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53110-1", "uniprot_id": "IMR_YEAST", "id": "P53110-1", "name": "Imine reductase", "aln": "--MNNSIITDDEVREFYLNCSSQTIIESLLSLHESLRLYSQNHEILLNRMFKKLDETNADSNISHIFMPVVSKDFSGIKILVNNNNKN-----FQGVINVIEPETGKLIGCFEAKQITAIRTALASCIGLYKQLSCSHDKLFRFENGTCYLTCFGTGLQAFWHIYIAIKLIMSGIVGESLKLVEINILYHNNMMSLDRLKSLKNLFGSNIKIELNQYQINDISSEGNGAVSNSDIIFGCLPTLEPNLFLRQLLNSKASVEQKHTYISLIGSYKPVMHECDKELIDKFKSDNESACILVDSREHTLLESGELIDSNIAPHNLIEIGELDTLKNTVLNLNEKGCKRTITLCKIVGLAVMDVALAKEFLSLRTKNTENKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::: **.:. **. :* .* : .: .:. : * . : : .. .: : .. . : : : :... . .*. : :::*..*.*:. ::.: *** *** .*.*. *::: .: * :*:*:**: * * : : .::: :* :. : *...:: ::. :.*. : **:.:*:*: : ** ** . : ::*. :*: :* :* *.**: .* : ***:* :* ***::: * : * :.: . : *::* : * :*:** * . ** . . :... ", "identical_positions": 65, "similar_positions": 127, "identity": "17.24%" }, { "cls_id": "homologset.agr.RGD:620944", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55210-1", "uniprot_id": "CASP7_HUMAN", "id": "P55210-1", "name": "Caspase-7", "aln": "MADDQGCIEEQGVEDSANEDS-------VDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTY----QYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPIN-DTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFES-QSDDPHFHEKKQIPCVVSMLTKELYFSQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97864-1", "uniprot_id": "CASP7_MOUSE", "id": "P97864-1", "name": "Caspase-7", "aln": "MTDDQDCAAELEKVDSSSEDG-------VDAKPDRSSIISSILLKKKRNASAGPVRTGRDRVPTY----LYRMDFQKMGKCIIINNKNFDKATGMDVRNGTDKDAGALFKCFQNLGFEVTVHNDCSCAKMQDLLRKASEEDHSNSACFACVLLSHGEEDLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPIN-DIDANPRNKIPVEADFLFAYSTVPGYYSWRNPGKGSWFVQALCSILNEHGKDLEIMQILTRVNDRVARHFES-QSDDPRFNEKKQIPCMVSMLTKELYFSR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQU7-1", "uniprot_id": "A0A8I5ZQU7_RAT", "id": "A0A8I5ZQU7-1", "name": "", "aln": "MLSFYYYREEGNSLPVASGGS-------LVLQ--RGLLPDGDTRKKKKNASMCPVSTTRDRVPTY----LYRMDFEKMGKCIIINNKNFDKATGMDVRNGTDKDAEALFKCFRSLGFEVTVYNDCSCAKMQDLLRRASEEDHSNSACFACVLLSHGEENLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPIN-DTDANPRYKIPVEADFLFAYSTVPGYYSWRNPGKGSWFVQALCSILNEHGKDLEIMQILTRVNDRVARHFES-QSDDPRFNEKKQIPCMVSMLTKELYFGR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O02002-1", "uniprot_id": "CASP1_DROME", "id": "O02002-1", "name": "Caspase-1", "aln": "MTDECVTRNYGVGIRSPNGSENRGSFIMADNTDAKGCTPESLVVGGATAASPLPANKFVARMPVERYASEYNMSHKHRGVALIFNHEFFDIPS-LKSRTGTNVDAQELKKAFENLGFAVSVHKDCKLRDILKHVGKAAELDHTDNDCLAVAILSHGEHGYLYAKDTQYKLDNIWHYFTATFCPSLAGKPKLFFIQACQGDRLDGGITLEKGVTETDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGSWYMQSLIRELNANGKKYDLLTLLTFVNQRVALDFESNVPATPMMDRQKQIPCLTSMLTRILRFGDKPNGNKAG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .. . :. . .: . . *:*. *.*..:: * .:*:*:: ** : : *.**: ** * *.*..*** * *::**. .: . : :*:* **:: *:* :*****.. :*.** :.:: :* . * :* **********:* .**.** :.* : * ::.. ***:.*****:***:***:***. ..***::*:* *: :**. ::: :** **:*** .*** . * :..:*****:.****: * *. ", "identical_positions": 106, "similar_positions": 93, "identity": "32.72%" }, { "cls_id": "homologset.agr.RGD:620945", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHX4-1", "uniprot_id": "CASP8_RAT", "id": "Q9JHX4-1", "name": "Caspase-8", "aln": "MDFHSCLYDIAERLGNEELAALKFLCLDHIPQKKQESINDVLVLFQRLQEEGMLEEDNLSFLKELLFHISRRDLLSRVLKSSPEEMVRELQVLGKAQVSAYRVMLFKLSEDMDKEDLKSFKFLLITEIPKCKLQDNSSLLDIFVEMEKRTILAENNLVTLKSICFRVNRSLLGRIDDYERSSTERRMSTEGG-EELPVSVLDEVTIKMQDMWDSPGEQESESLNSDNVYQMKSKPRGYCLIFNNNNFSKAREDIPKLSNMRDRKGTNYDEEALSKTFKELHFEIVSFSDCTASQIHEVLVSYQSKDHKGKDCFICCILSHGDKGIVYGTDGKEASIYELTSYFTGSKCPSLAGKPKIFFIQACQGNNFQKAVPVPDETGLEQ-EHVLEEDSSSYKN-YIPDEADFLLGMATVKNCVSYRDPTRGTWYIQSLCQSLRERCPRGEDILSILTGVNYDVSNKDNPRNMGKQMPQPIFTLRKKLFFPPN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89110-1", "uniprot_id": "CASP8_MOUSE", "id": "O89110-1", "name": "Caspase-8", "aln": "MDFQSCLYAIAEELGSEDLAALKFLCLDYIPHKKQETIEDAQKLFLRLREKGMLEEGNLSFLKELLFHISRWDLLVNFLDCNREEMVRELRDPDNAQISPYRVMLFKLSEEVSELELRSFKFLLNNEIPKCKLEDDLSLLEIFVEMEKRTMLAENNLETLKSICDQVNKSLLGKIEDYERSSTERRMSLEGR-EELPPSVLDEMSLKMAELCDSPREQDSESRTSDKVYQMKNKPRGYCLIINNHDFSKAREDITQLRKMKDRKGTDCDKEALSKTFKELHFEIVSYDDCTANEIHEILEGYQSADHKNKDCFICCILSHGDKGVVYGTDGKEASIYDLTSYFTGSKCPSLSGKPKIFFIQACQGSNFQKG--VPDEAGFEQQNHTLEVDSSSHKN-YIPDEADFLLGMATVKNCVSYRDPVNGTWYIQSLCQSLRERCPQGDDILSILTGVNYDVSNKDDRRNKGKQMPQPTFTLRKKLFFPP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14790-1", "uniprot_id": "CASP8_HUMAN", "id": "Q14790-1", "name": "Caspase-8", "aln": "MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSN---GEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKG--IPVETDSEE-QPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** *.*.*..*:**:****.**:**::***.*:*. ** **:*: ****.**********:*.* *** *. *** ***: ..**:*.*****:::**::.. :*:****** **.****:*: .**:**:*****.:*.*.:* ** :* ::*:*** *:***. *.** * ** :*:. .* : : *** **:*** . *:*****.********:**::*:****.:.:* .::**:**. * **:.**:****** ...***..:*:*:* ** **.. **************::*****:**.**:*** *** *****:****:********.*:**. :* *:. *: : ** * ** :. ***************:******:*..*****************:*:***:*** ***:*****: :* ******* *******.**. ", "identical_positions": 293, "similar_positions": 116, "identity": "60.41%" }, { "cls_id": "homologset.agr.RGD:620946", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88939-1", "uniprot_id": "ZBT7A_MOUSE", "id": "O88939-1", "name": "Zinc finger and BTB domain-containing protein 7A", "aln": "MAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFKKLFTSGAVVDQQNVYEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAARLLEIPAVSHVCADLLERQILAADDVGDASQPDGAGPTDQRNLLRAKEYLEFFRSNPMNSLPP------TAFPWSGFGAPDDDLDATKEAVAAAVAAVAAGDCNGLDFYGPGPPADRPPAGDGDEGDSTPGLWPERDEDAPPGGLFPPPTAPPATTQNGHYGRAGAGTGEEEAAALSEAAPEPGDSPGFLSGAAEGEDGDAADVDGLAASTLLQQMMSSVGRA----GDSDEESRTDDKGVMDYYLKYFSGAHEGDVYPAWSQKGEKKIRAKAFQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQCDSCCKTFVRSDHLHRHLKKDGCNGVPSRRGRKPRVRGVPPDVPAGAGAPPGLPDAP------RNGQEKHFKDEEEDEEEASPDGSGRLNVAGSGGDDGAGGPAVATAEGNFAT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QZ48-1", "uniprot_id": "ZBT7A_RAT", "id": "Q9QZ48-1", "name": "Zinc finger and BTB domain-containing protein 7A", "aln": "MAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFKKLFTSGAVVDQQNVYEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAARLLEIPAVSRVCTDLLERQILAADDVGDAGQPDGAGPTDQRNLLRAKEYLEFFRSNPMNSLPP------TAFQWPGFSAPDDDLDATKEAVAAAVAAVAAGDCNGLDFYGPGPPADRPPTGDGEEGDSTPGLWPERDEDAPPGGLFPPPTAPPATTQNGHYGRAGASTGEEEAVALSEAAPEPGDSPGFLSGAAEGEDGDAADVDGLAASTLLQQMMSSVGRA----GDSDEESRPDDKGVMDYYLKYFSGAHEGDVYPAWSQKGEKKIRAKAFQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQCDSCCKTFVRSDHLHRHLKKDGCNGVPSRRGRKPRVRGVPPDVPSGAGAPPGLPDAP------RNGQEKHFKDEEDDEEEASLDGLGRLNVAGSGGDDGAGGPTVAATEGNFAT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95365-1", "uniprot_id": "ZBT7A_HUMAN", "id": "O95365-1", "name": "Zinc finger and BTB domain-containing protein 7A", "aln": "MAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFKKLFTSGAVVDQQNVYEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAARLLEIPAVSHVCADLLDRQILAADAGADAGQLDLVDQIDQRNLLRAKEYLEFFQSNPMNSLPPAAAAAAASFPWSAFGASDDDLDATKEAVAAAVAAVAAGDCNGLDFYGPGPPAERPPTGDGDEGDSNPGLWPERDEDAPTGGLFPPPVAPPAATQNGHYGRG----GEEEAASLSEAAPEPGDSPGFLSGAAEGEDGDGPDVDGLAASTLLQQMMSSVGRAGAAAGDSDEESRADDKGVMDYYLKYFSGAHDGDVYPAWSQKVEKKIRAKAFQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQCDSCCKTFVRSDHLHRHLKKDGCNGVPSRRGRKPRVRGGAPDPSPGATATPGAPAQPSSPDARRNGQEKHFKDEDEDEDVASPDGLGRLNVAGAGGGGDSGGGPGAATDGNFTAGLA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************************************************************************************************:**:***:******* .**.* * .. ***************:********* ::* *..*.*.***********************************:***:***:****.************.*******.****:********. *****.:*************************..********************* ********.*****************:********** ************************************************************************************************************************************* .** ..** *.** * * ***********::**: ** ** *******:**...:** . *:::***:: ", "identical_positions": 500, "similar_positions": 46, "identity": "85.03%" }, { "cls_id": "homologset.agr.RGD:620948", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50554-1", "uniprot_id": "GABT_RAT", "id": "P50554-1", "name": "4-aminobutyrate aminotransferase, mitochondrial", "aln": "MAFLLTTRRLVCSSQKNLHLFTPGSRYISQAAAKVDFEFDYDGPLMKT-EVPGPRSQELMKQLNTIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYNHPALAKLVQQPQNASTFINRPALGILPPENFVDKLRESLMSVAPKGMCQLITMACGSCSNENAFKTIFMWYRSKERGQ-RGFSKEELETCMVNQSPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVTDNQQEEARCLEEVEDLIVKYRKKKRTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMSFSKKMMTGG-FFHKEEFRPSAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNVAHAGKTLLTGLLDLQAQYPQFVSRVRG--RGTFCSFDTPDEAIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSGILADFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61922-1", "uniprot_id": "GABT_MOUSE", "id": "P61922-1", "name": "4-aminobutyrate aminotransferase, mitochondrial", "aln": "MAFLLITRRLACSSQKNLHLFIPGSRYISQAAAKVDIEFDYDGPLMKT-EVPGPRSKELMKQLNTIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYNHPALAKLVQQPQNASTFINRPALGILPPENFVDKLQESLMSVAPRGMSQLITMACGSCSNENAFKTIFMWYRSKERGQ-RGFSKEELETCMVNQSPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFTTDNQQEEARCLEEVEDLIVKYRKKKRTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGG-FFHKEEFRPSAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNVARVGKTLLTGLLDLQAQYPQFISRVRG--RGTFCSFDTPDEAIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLSIFSGILADFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P80404-1", "uniprot_id": "GABT_HUMAN", "id": "P80404-1", "name": "4-aminobutyrate aminotransferase, mitochondrial", "aln": "MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKT-EVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQ-RGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGG-FFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRG--RGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3IRW7-1", "uniprot_id": "I3IRW7_DANRE", "id": "I3IRW7-1", "name": "4-aminobutyrate aminotransferase, mitochondrial", "aln": "MASSLLTRQLALSLQQNLRLAAPGSRYVSKTATKTVSEFEYDAPSMKT-TVPGPKSKELLRQLGEIQNTGAIHFFCNYEESRGNYLVDVDGNRMLDVYTQISSIPIGYNHPALMKVMTNPNNVSAFVNRPALGILPPENFPEKLAESLLSIAPSGMTKVQTMACGSCSNENAFKSMFIWYRNKERGY-ATPSEEEVGTCMVNQSPGCPDLSILSFMGAFHGRTLGCLATTHSKAIHKLDIPSFDWPIAPFPKLRYPLEEFERENAQEEARCLEEVEDLIVKWRQKGKPVAGIVIEPIQAEGGDNHASPDFFIKLRNIARKHGCGFHVDEVQTGGGATGKFWAHEHWGLDDPADLVSFSKKMLTGG-YFHRDELQPDKPYRIFNTWMGDPSKNLFLSEVLNVIRRENLLEQVTRSGKALLQGLYALQSQYPHLLSGARG--QGTFCAINASSDATRDSIMLKARNKGVFLGSCGEKSIRFRPALVFKEYHVHQLLNILNDVLAEHK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW68-1", "uniprot_id": "Q9VW68_DROME", "id": "Q9VW68-1", "name": "(S)-3-amino-2-methylpropionate transaminase", "aln": "MRSLWLN---TLTKQSLYRLST--KRYSTNVEPKE--------PVVKTKSIPGPKSIELKKQLDSVQATGTIQFFADYEKSIGNYIYDVDGNILLDVYTQISSVPLGYNHPRLYKVFNNEQNLKTLINRPALGVFPGKEWPEKLHSVLLNIAPKGLNKITTMMCGSCSNENAYKSIFIWYQNKLRGN-APLTEQEKNSCMINIPPGAPKLSILSFKGAFHGRTLGALSTTHSKYIHKLDVPSFDWPIASFPEYRYPLDENVAHNKKEDEKCLSEVQDLIQQYASKN-PVAGIVVEPIQSEGGDNEASPEFFRSLQAICKKNGIALLIDEVQTGGGSTGKFWAHEHFELESPPDVVTFSKKLQLGG-YFHNDDFIPNEPYRIFNTWMGDPGKVLLLEEVVKVIQEEKLLANVDVAGKVLKNGLLSLEKEFPHILNSTRG--RGTFLAVNCTNTKVRDQIIGALKLHGIQTGGCGEISIRFRPALIFKEYHANIVLDRFRKVLQGI-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P17649-1", "uniprot_id": "GABAT_YEAST", "id": "P17649-1", "name": "4-aminobutyrate aminotransferase", "aln": "--------------------MSICEQYYPEEPTKP---------TVKTESIPGPESQKQLKELGEVFDTRPAYFLADYEKSLGNYITDVDGNTYLDLYAQISSIALGYNNPALIKAAQSPEMIRALVDRPALGNFPSKD-LDKILKQILKSAPKGQDHVWSGLSGADANELAFKAAFIYYRAKQRGYDADFSEKENLSVMDNDAPGAPHLAVLSFKRAFHGRLFASGSTTCSKPIHKLDFPAFHWPHAEYPSYQYPLDENSDANRKEDDHCLAIVEELIKTW---SIPVAALIIEPIQSEGGDNHASKYFLQKLRDITLKYNVVYIIDEVQTGVGATGKLWCHEYADIQPPVDLVTFSKKFQSAGYFFHDPKFIPNKPYRQFNTWCGEPARMIIAGAIGQEISDKKLTEQCSRVGDYLFKKLEGLQKKYPENFQNLRGKGRGTFIAWDLPTGEKRDLLLKKLKLNGCNVGGCAVHAVRLRPSLTFEEKHADIFIEALAKSVNEL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: .: .* :** :***.* : ::*. : : . *:.:**:* ***: ***** **:*:****:.:**.:* * * . : :::***** :* :: :*: . ::. ** * :: : .*: :** * *: *::*: * ** :::* : * * .**.*. ::*** ***** :.. :** ** ***:*.*:*.** * :* :***:* * :*: :** *::** : .**.:::****:*****.** *: .*: * * . :****** *.***:*.**: :: * *:::****: .* :** .: *. *** **** *:*.: :: : : * :.* : *. * * *: .:*. .. ** :*** : : . *: :: : :* *.*. ::*:**:* *.: *.. .:. : : ", "identical_positions": 162, "similar_positions": 146, "identity": "32.08%" }, { "cls_id": "homologset.agr.RGD:620949", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VGT2-1", "uniprot_id": "Q9VGT2_DROME", "id": "Q9VGT2-1", "name": "UDP-glucuronosyltransferase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLASGLFYLIILLFPGFLYGAR---------ILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFP----SEEPVKNIYDIYVPEVLNS-------------FDELLKQMTTPKNT---WEFFDATNEFVYNITKDVFNNDGV--------------------------------------------RREILRPGKA-------QFDLIIVDIWKYDAFYSLAAYFEAPIIGLAPCGIDWKIDEMVGNPSPMSYLQSPSSYLYNLDTFGGRVAHVVEVAISWFNWHWRYEQ-KHEALYKKYFPKIAE------------TKPLSEISQDIALVLVNQHFT-LGPPRPYVPN------------------------------VIEVGGMHIDEQPKALAQDLEDFIQGSGEHGVIYFSLG-------------------------------------------------------TNVRTKNMVDDRKRILIEAFGS-----------------------------LPQRVLWK---------------FEDEE-LQDIPSNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFC-----LSLNYHDMTSDELKATILQLLTEKRFEVTARIAGARYRDQPM---------KPLETAVWWTHYVLRHKG------------APHMRVAGRKLSFFTHHSLDVLGTVLL--VILLVIIAILLIIVFSVCKISKNISTRLVVKKQRKQKVR-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9X9-1", "uniprot_id": "Q9V9X9_DROME", "id": "Q9V9X9-1", "name": "UDP-glucuronosyltransferase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPP---IFLLVCLLPGYSEGAR---------ILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYP----QREPFRNIHDIPVPEVFEN-------------FNEVLRIASTPRST---WQSSDFINEYVLNLTKTVLNNEGV--------------------------------------------RRDILGPQKP-------HFDLVIMDLWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNVSPISYLQSPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVR-KQETLYSQFFPSVAE------------RKPLSEISRNFDLVLVNQHFT-LGPPRPYVPN------------------------------MIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYFSLG-------------------------------------------------------TNVKSKSLSEDRRKVLLETFAS-----------------------------LPQRIVWK---------------FEDEL-LPGKPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLG-----LVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPM---------KPMETAIWWTEYVLSHKG------------AAHMQVAGKDLGFVRYHSLDVFGTFLVGALVILGIVTYLLVMTLRKCLFLIKRGKCEAIKKIQ----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT3-1", "uniprot_id": "Q9VGT3_DROME", "id": "Q9VGT3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPTAGQTGFLALLLFCLLSCVSAYN---------YLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFE----LKKPIKNIKDVPAKSILTS-------------MQGRIANLLQSSKE---PIIKQIINFHEMGIEITELLLKEP--------------------------------------------SVIELMKSNQ-------TFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPSYVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLP-RQEVLYRKYFP--NN------------KQDFYDMRKNTALVLLNQHVS-LSFPRPYSPN------------------------------MIEVGGMHINRKRQPLPKDILEFIEG-AEHGVIYFSMG-------------------------------------------------------SNLKSKTLPLEKRQALIDTFAQ-----------------------------LKQRVLWK---------------FEDTD-LPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYG-----VTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQ---------TPLERAVYWVEHVSRHKG------------AKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIRLVWRLLQELFIKKDTSKPKQKAKRN-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG30-1", "uniprot_id": "Q9VG30_DROME", "id": "Q9VG30-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHKSGIYLLLATAICVLGGCHGAN---------ILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLK----PVVNHKNITVIMVPLTKEESQQ----------MSDTIGAMSKTDNSNMILSMLRMMGQMEFMFDKMAGALKDD--------------------------------------------RVRDLYLNRDN------KFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGNPLEIAYVPSISDSVEKGKGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKELFGDDPN------------MPEYSELVKNTSLIFFASHAPSEGPIRPNVPA------------------------------AIEIGGIQVKDTPDPLPQNMAEFLGN-ATDGAILLSLG-------------------------------------------------------SNVKGSHINPDTVVKMFNVLSK-----------------------------LKQRVIWK---------------WEDLEKTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFG-----LTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPM---------SARESVIYWTEYVIRHHG------------AAHLQSPLVHMSFIAANNIDIYALIAVVLVILVLLLKLLLQFIYRKIFAKPKK---EKKH-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJI0-1", "uniprot_id": "Q9VJI0_DROME", "id": "Q9VJI0-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIGVHFVFLLLLGVVASTQGAN---------ILGLFSSHSPSHLIIHMSVAKALVKAGHNVTVVSMLK----PKVTHKDIHLIVVPMKEEQERI----------MEDQMTEMAGQKNS-LVSTMYRLLTSMDVMINAQAELLSDP--------------------------------------------RFQRIYET---------KFDLMILGYFINDFQLGVAHKLKVPVIINWMSAPVPAIDKYTGNPSELSYVPLMGTVATQP--MGFLKRTENALKSLLFEFIFVVFDYKLTRIYNDVFPEQ-D------------MPTLKELRKNISMAFVGSHLISEGPIRPLVPA------------------------------LIEIGGIQVKDKPDPLPKDIDQFISN-AKQGAVFLSLG-------------------------------------------------------SNVKSSTVRPEIVQIIFKVLSE-----------------------------LKENVIWK---------------WEDLENTPGNSSNILYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYG-----LALDLLSITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPM---------TAKQSVVFWTEYILRHQG------------APNLQSPSVHMNFIQLNNLDIYALIVTILVLFVLLTRLVAKIVWNKFGGKAKISQTKKKQ-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q64435-1", "uniprot_id": "UD16_MOUSE", "id": "Q64435-1", "name": "UDP-glucuronosyltransferase 1A6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MACLLPAAQTLPAGFLFLVLWASVLG---------DKLLVVPQDGSHWLSMKEIVEHLSERGHDIMVLVPEVNLLLGESKYYRRKIFSVTYSLEE-------------LQTRFRTFGNNHFLPG-ASLMGPLREYRNNMIVVD-MFFSN--------------------------------------------CQSLLKDSATLSFLRENKFDALFTDPAMPCGVI-LAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSK--YEIIASDLLKR---------------DVSLPSLHQN-SLWLLRYDFV-FEYPRPVMPN------------------------------MIFLGGINCK-KKGKLTQEFEAYVNASGEHGIVVFSLG-------------------------------------------------------SMVS--EIPEKKAMEIAEALGR-----------------------------IPQTVLWR---------------YTGTR-PSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAG-----VTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPI---------EPLDLAVFWVEYVMRHKG------------APHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K9J7B2-1", "uniprot_id": "K9J7B2_MOUSE", "id": "K9J7B2-1", "name": "UDP-glucuronosyltransferase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MACLLPAAQTLPAGFLFLVLWASVLG---------DKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYYRRKIFSVPYSLEE-------------LQTRFRTFGRNQFVPG-APLMGPLREYRNSMLTLE-MFFSN--------------------------------------------CQSLLKDSATLSFLRENKFDALFTDPAMPCGVI-LAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSK--YEIIVTDLLKR---------------DVSLPSLHQN-SLWLLRYDFV-FEYPRPIMPN------------------------------MIFIGGINCK-KKGKLTQEFEAYVNASGEHGIVVFSLG-------------------------------------------------------SMVS--EIPEKKAMEIAEALGR-----------------------------IPQTVLWR---------------YTGTR-PSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAG-----VTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPI---------EPLDLAVFWVEYVMRHKG------------APHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08430-1", "uniprot_id": "UD16_RAT", "id": "P08430-1", "name": "UDP-glucuronosyltransferase 1A6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MACLLPAAR-LPAGFLFLVLWGSVLG---------DKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYYRRKSFPVPYNLEE-------------LRTRYRSFGNNHFAAS-SPLMAPLREYRNNMIVID-MCFFS--------------------------------------------CQSLLKDSATLSFLRENQFDALFTDPAMPCGVI-LAEYLKLPSIYLFRGFPCSLEH-IGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIANILENYLYHCLYSK--YEILASDLLKR---------------DVSLPALHQN-SLWLLRYDFV-FEYPRPVMPN------------------------------MIFIGGTNCK-KKGNLSQEFEAYVNASGEHGIVVFSLG-------------------------------------------------------SMVS--EIPEKKAMEIAEALGR-----------------------------IPQTLLWR---------------YTGTR-PSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAG-----VTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPI---------EPLDLAVFWVEYVMRHKG------------APHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19224-1", "uniprot_id": "UD16_HUMAN", "id": "P19224-1", "name": "UDP-glucuronosyltransferase 1A6", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MACLLRSFQRISAGVFFLALWGMVVG---------DKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLKESKYYTRKIYPVPYDQEE-------------LKNRYQSFGNNHFAER-SFLTAPQTEYRNNMIVIG-LYFIN--------------------------------------------CQSLLQDRDTLNFFKESKFDALFTDPALPCGVI-LAEYLGLPSVYLFRGFPCSLEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSK--YEELASAVLKR---------------DVDIITLYQKVSVWLLRYDFV-LEYPRPVMPN------------------------------MVFIGGINCK-KRKDLSQEFEAYINASGEHGIVVFSLG-------------------------------------------------------SMVS--EIPEKKAMAIADALGK-----------------------------IPQTVLWR---------------YTGTR-PSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAG-----VTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPV---------EPLDLAVFWVEFVMRHKG------------APHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NVN7-1", "uniprot_id": "A0A8M1NVN7_DANRE", "id": "A0A8M1NVN7-1", "name": "UDP-glucuronosyltransferase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASVL---------LFCLFCLASAKA---------GKILVVPSDGSHWMGIKPLVEELGRRGNQVVVVIPEASLSMGPSQHTTTLTYPVPYTKAQ-------------IQDHISASVTNLISTHVSTDLARFQSFINTMDLLSNLITRN--------------------------------------------VEGLLLNKDLMKKLQDYNFDVILTDPFETVGVI-AAEYLSIPTIYIQTSHPCGADTLASQCPSPPSYVPQRLTHFSDRMNLWQRSVNFVRTLIQPMACRRMFTR--ADEIASRVLQR---------------KTSIMDIMGRAALWFVHSDFA-LEFPHPLMPN------------------------------MIIVGGMDNR-KAEPLSQELEEFVNGSGEHGFVVFTLG-------------------------------------------------------SMVS--QLPEAKAREFFEAFRQ-----------------------------IPQRVLWR---------------YTGPV-PENAPKNVKLMKWLPQNDLLGHPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVSRGVA-----ESLTIYDVTSEKLLVALKKVINDKSYKEKMMKLSAIHRDRPI---------EPLDLAVFWTEFVMRHKG------------AEHLRPAAHDLNWIQYHSLDVIGFLLLILLTVIFVTVKSCMFCFRKCFKKSQKKKKA----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06321-1", "uniprot_id": "ATG26_YEAST", "id": "Q06321-1", "name": "Sterol 3-beta-glucosyltransferase", "aln": "MPITQIISASDSEAGPKPSISLVPDKPSEPETSPRHHRLSRSLSKFKRWRGRSNSSLSMGSSEQQELQDSPNEARSDDDENGYNNDNADDLAKSKYMMKSIAGLLTTASVYAGMNNAQEMNVLSQVDSEESDSSDSFQENIGRNEVKSKKENLKTKSHPEVPRLDKRKPTLFDFSITREKLSKDNVAKLRQRFCLDEQEPFLNDFPAWLLKDVLVQGHIFITTKHFLFFAYLPKNPRSVKMSGNLNIRTKLIRSTRYWCVLKNHLFSMYTSSTELYFPVLTIDLREVQKIETQKHTLNGSATKTFKLYTDESTFKFNADSEFSAKSWVNALKKEQFAAQNSENNSISLKIPLPNIIEIDDQPIVNKALTLRLRALESSQTYAIDDFMFVFMDGSGSQVKESLGEQLAILQKSGVNTLYYDIPAKKSKSSFGKETPATVEQKN-NGEDSKYLNVPTSAVPSSENGKKSRFRFRERSNSWFRRAKPLEDSQVEDVEEIYKDAANDIDSSVHSTIHIHEQEDSQEQTVAWKPSHLKNFAEMWAAKPIHYRNKFIPFQKDDTYLIKETEEVSANERFRYHFKFNKEKSLISTYYTYLNRNVPVYGKIYVSNDTVCFRSLLPGSNTYMVLPLVDVETCYKEKGFRFGYFVLVIVIHGHEELFFEFSTEVARDDIERILLKLLDNIYASSAEGSNISSASLGDVQHNPDSAKLKLFEDKINAEGFEVPLMIDENPHYKTSIKPNKSYKFGLLTIGSRGDVQPYIALGKGLIKEGHQVVIITHSEFRDFVESHGIQFEEIAGNPVELMSLMVENESMNVKMLREASSKFRGWIDALLQTSWEVCNRRKFDILIESPSAMVGIHITEALQIPYFRAFTMPWTRTRAYPHAFIVPDQKRGGNYNYLTHVLFENVFWKGISGQVNKWRVETLGLGKTNLFLLQQNNVPFLYNVSPTIFPPSIDFSEWVRVTGYWFLDDKSTFKPPAELQEFISEARSKGKKLVYIGFGSIVVSNAKEMTEALVEAVMEADVYCILNKGWSERLGDKAAKKTEVDLPRNILNIGNVPHDWLFPQVDAAVHHGGSGTTGASLRAGLPTVIKPFFGDQFFYAGRVEDIGVGIALKKLNAQTLADALKVATTNKIMKDRAGLIKKKISKEDGIKTAISAIYNELEYARSVTLSRVKTPRKKEENVDATKLTPAETTDEGWTMI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. . : *:: . . : : : . : : : : :. . * : :* : : * :. : : : .: : : :.*: * .. : :: * : * : : : * . . : : : . : . : . .. * * . :: . : . * . : ", "identical_positions": 12, "similar_positions": 65, "identity": "1.0%" }, { "cls_id": "homologset.agr.RGD:620950", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HAW8-1", "uniprot_id": "UD110_HUMAN", "id": "Q9HAW8-1", "name": "UDP-glucuronosyltransferase 1A10", "aln": "--MARAGWTSPVPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQS---IFSLLMSSSSGFLDLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDTCG-LIVAKYFSLPSVVFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFRN-----ALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCH-QGKPLPMEFEAYINASGEHGIVVFSLGSMVS--EIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HAW7-1", "uniprot_id": "UD17_HUMAN", "id": "Q9HAW7-1", "name": "UDP-glucuronosyltransferase 1A7", "aln": "--MARAGWTGLLPLYVCLLLTCGFAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARWTAPLRS---AFSLLTSSSNGIFDLFFSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACG-LIVAKYFSLPSVVFARGIFCHYLEEGAQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKN-----VLEIASEILQTPVTAYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCH-QGKPVPMEFEAYINASGEHGIVVFSLGSMVS--EIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HAW9-1", "uniprot_id": "UD18_HUMAN", "id": "Q9HAW9-1", "name": "UDP-glucuronosyltransferase 1A8", "aln": "--MARTGWTSPIPLCVSLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGKSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQVRS---LFSLFLSSSNGFFNLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACG-LIVAKYFSLPSVVFARGIACHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKN-----ALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCH-QGKPLPMEFEAYINASGEHGIVVFSLGSMVS--EIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O60656-1", "uniprot_id": "UD19_HUMAN", "id": "O60656-1", "name": "UDP-glucuronosyltransferase 1A9", "aln": "--MACTGWTSPLPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMRSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDLDREFKAFAHAQWKAQVRS---IYSLLMGSYNDIFDLFFSNCRSLFKDKKLVEYLKESSFDAVFLDPFDNCG-LIVAKYFSLPSVVFARGILCHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLLCHRFFKN-----ALEIASEILQTPVTEYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCH-QGKPLPMEFEAYINASGEHGIVVFSLGSMVS--EIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64633-1", "uniprot_id": "UD17_RAT", "id": "Q64633-1", "name": "UDP-glucuronosyltransferase 1A7", "aln": "--MAPADVPASLPLGLCLLLASGFGHAGKLLVVPMDGSHWFTMQMVVEKLLPKGHEVVVVVPEVSWQLGKPLNFTVKTYSVSHTQEDLNREFKFFIDSQWKTQQESG--VLPLLTSPAQGFFELLFSHCRSLFKDKKLVEYLKQSSFDAVFLDPFDVCG-LTVAKYFSLPSVVFSRGIFCHYLEEGSQCPSPPSYVPRPILKLTDTMTFKERVWNLLSYMGEHAFCPSFFKT-----ATDIASEVLQTPVTMTDLFSPVSVWLLRTDFTLELPRPVMPNVIHIGGINCH-QRKPVSKEFEAYVNASGEHGIVVFSLGSMVS--EIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQM8-1", "uniprot_id": "UD17_MOUSE", "id": "Q6ZQM8-1", "name": "UDP-glucuronosyltransferase 1A7", "aln": "--MAPADFPASLPLCVCLLLASGLAQAGRLLVVPMDGSHWFTMQTVVEKLLHKGHEVVVVVPEVSWQLTKPLNFVVKTYAVSHTQEDLNREFKIFIDAQWKSQQEGG--ILPLLDSPAKGFFELLFSHCRSLFNDKKLVEYLKQTSFDAVFLDPFDVCG-LTVAKYFSLPSVVFSRGIFCHYLEDAAQCPSPPSYIPRMLLKFTDTMTFKERTRNLLAYMGERAFCHKFFKS-----AADIASEVLQTPVTMTDLFSPVSIWLLRTDFVLEFPRPVMPNVIYIGGINCH-QGKPLSKEFEAYVNASGEHGIVVFSLGSMVS--EIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1NVN7-1", "uniprot_id": "A0A8M1NVN7_DANRE", "id": "A0A8M1NVN7-1", "name": "UDP-glucuronosyltransferase", "aln": "--------MASVLLFCLFCLAS--AKAGKILVVPSDGSHWMGIKPLVEELGRRGNQVVVVIPEASLSMGPSQHTTTLTYPVPYTKAQIQDHISASVTNLISTHVSTDLARFQSFINTMDLLSNLITRNVEGLLLNKDLMKKLQDYNFDVILTDPFETVG-VIAAEYLSIPTIYIQTSHPCGADTLASQCPSPPSYVPQRLTHFSDRMNLWQRSVNFVRTLIQPMACRRMFTR-----ADEIASRVLQRKTSIMDIMGRAALWFVHSDFALEFPHPLMPNMIIVGGMDNR-KAEPLSQELEEFVNGSGEHGFVVFTLGSMVS--QLPEAKAREFFEAFRQIPQRVLWRYTGPVPENAPKNVKLMKWLPQNDLLGHPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVSRGVAESLTIYDVTSEKLLVALKKVINDKSYKEKMMKLSAIHRDRPIEPLDLAVFWTEFVMRHKGAEHLRPAAHDLNWIQYHSLDVIGFLLLILLTVIFVTVKSCMFCFRKCFKKSQKKKKA------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2J4-1", "uniprot_id": "Q9W2J4_DROME", "id": "Q9W2J4-1", "name": "UDP-glucuronosyltransferase", "aln": "MSLKSALHIFLLSLVALQQLELGTGSRILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGSNYKEIVIPQYDFWPEIKEMTNKNTVLEMTDLPTFA----FLRMVN-VMGIHTTDFALEQPEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFGVVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQ-PPKALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICRRSSK---PKSTPTKKKTKKN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDA5-1", "uniprot_id": "Q9VDA5_DROME", "id": "Q9VDA5-1", "name": "UDP-glucuronosyltransferase", "aln": "-------MILFMKLLFVCLLGTGDGARILAPFFLPVKSHFMMTDAIIRELVKRGHEVTFITPLSLAKENLGPNYREILLPKYDTWADISAMMKTKSALDMIDMSKLT----HMRLAQ-HIGIKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYANYFSQVFGFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHIL-PPKPLPEHIKNYLDNA-EHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLDVSAIILAITLLPLLTLYAVSRNYKS---FRGIRAQKKEAKTE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT5-1", "uniprot_id": "Q9VGT5_DROME", "id": "Q9VGT5-1", "name": "UDP-glucuronosyltransferase", "aln": "------MRTFTLILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPG--YTDVSVPN-----VIEVMGGDIGALWASIQKTYT----QNLIDHYQMGFRITRGLFEDSNFQDFLKSNQS---FDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFP---GNKRCFYKMRRNASLVLINQHVSLSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINES-EHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLPITIYKLLKKLLLKGERTQSTKVKRN-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * . . **: : . * *: :..: . . . : : . :* :: : * . . . * : : * *::*. .* *.: :* * : . . .: : ::. . * .:* *:* :**:. :.:. .:: ::: : ** : *::** : ::* * : ..: : * :**:: * . *. : .*:** *:*.** .*::*.* . *.: :. *:: :*.: ** * . * :. .: : : .: .* : * .:*: .:: *::* :.* .*:** :* .*. * * *:: :*: : : : : . :. ", "identical_positions": 66, "similar_positions": 132, "identity": "12.13%" }, { "cls_id": "homologset.agr.RGD:620951", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1I6-1", "uniprot_id": "ARHG1_RAT", "id": "Q9Z1I6-1", "name": "Rho guanine nucleotide exchange factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGEVAGGAA-PGPPR-----------------------------SGLVSI--IIGAEDEDFENELEANPEDQNSQFQSLEQVKRRPAHLMALLQHVALQFEPGPLLCCLHADMLSSLGPKEAKKAFLDFYHSFLEKTAVLRVPVP-PSVAFELD-RTRPDLISEDVQRRFIQEVVQSQQAAVTRQLEDFRSKRLMGMTPWEQELSLLEPWIGKDRGNYEARERHVAERLLSHLEEMQHTISTDEEKSAAVVTAISLYMRHLGVR-------TKSGDKKSGRNFFRKKV----------------------------------------------------------------------------------------MGNRRSDEPPKTKKGLSSILDPARWN--------RGEPS------------APDCR-----------HLKVEVD-EKPGPADRKGS---LGISSRDRTVGTPGQDNPGVS---------------------------------------LHPLSVDSLDSREPGVDTPQEP---GDTPPQGPTSLEPLAPPE----STEDNGETESPEPGDDGEPGRSGLEQEP------------------------------------------------------------------EEPPGWRELVPSDTLLGLPKNQVKRQEVISELLVTEAAHVRMLRVLHDLFYQPMAEGGFFPLEELQNIFP-SLDELIEVHSLFLDRLMKRRQESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQN-----TEEPAERAKVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLTHLRQSNDPMLSEFKNLDITKKKLVHEGPLTWRLTKDKAVEVHVLLLDDLLLLLQRQDEGCCSSHTSRTLTPTPDGKTMLRPVLRLTS-AMTREVATDHKAFYVIFTWDQEAQIYELVAQTSSERKSWCALITETAGSLKVPAP---------------------------------------------------------------------------------------------ASRPKPRPSPS------------STREPLLSSSENGTGGTEAAP------------------------------------------------------------------ADARTERILN--------------DLLPFC-------------------------RPGPEGQLAATALQKVLSLKQILLSTE----------EDSGAGP-PRDGDG----VPGGGAPGPTHTQEVEENLLSLEVVIK--------QLEELEEEFCRLRP------FLSQLG-------EILSPNLAAPERSAQTGLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61210-1", "uniprot_id": "ARHG1_MOUSE", "id": "Q61210-1", "name": "Rho guanine nucleotide exchange factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGEVAGGAA-PGPPR-----------------------------SGLVSI--IIGAEDEDFENELEANSEDQNSQFQSLEQVKRRPAHLMALLQHVALQFEPGPLLCCLHADMLSSLGPKEAKKAFLDFYHSFLEKTAVLRVPVP-PSVAFELD-RTRPDLISEDVQRRFIQEVVQSQQAAVSRQLEDFRSKRLMGMTPWEQELSLLEPWIGKDRGNYEARERHVAERLLSHLEETQHTISTDEEKSAAVVTAISLYMRHLGVR-------TKSGDKKSGRNFFRKKV----------------------------------------------------------------------------------------MGNRRSDEPPKTKKGLSSILDPARWN--------RGEPS------------APDCR-----------HLKVEADAEKPGPADRKGG---LGMSSRDRTVGTPGQDNPGVS---------------------------------------LHPLSTDSVDSREPGVDTPQEP---GDTPPQGPTSLEPLAPPE----STEDNGETESPEPGDDGEPGRSGLELEP------------------------------------------------------------------EEPPGWRELVPPDTLLSLPKSQVKRQEVISELLVTEAAHVRMLRVLHDLFYQPMADGGFFPLDELQNIFP-SLDELIEVHSLFLDRLMKRRQESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQN-----TEESTERGKVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLTHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKDKAIEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTS-AMTREVATDHKAFYVIFTWDQEAQIYELVAQTSSERKNWCNLITETAGSLKVPAP---------------------------------------------------------------------------------------------ASRLKPRPSPS------------SIREPLLSSSENGTGGAEMAP------------------------------------------------------------------ADARTERLLN--------------DLLPFC-------------------------RPGPEGQLAATALQKVLSLKQILLSTE----------EDSGAGP-PRDGDG----VPGGRAPGPVHTQEIEENLLSLEVAIR--------QLEELEEEFCRLRP------LLSQLG-------GTLSPNLAAPERSAQTGLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92888-1", "uniprot_id": "ARHG1_HUMAN", "id": "Q92888-1", "name": "Rho guanine nucleotide exchange factor 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDFARGAASPGPSR-----------------------------PGLVPVS-IIGAEDEDFENELETNSEEQNSQFQSLEQVKRRPAHLMALLQHVALQFEPGPLLCCLHADMLGSLGPKEAKKAFLDFYHSFLEKTAVLRVPVP-PNVAFELD-RTRADLISEDVQRRFVQEVVQSQQVAVGRQLEDFRSKRLMGMTPWEQELAQLEAWVGRDRASYEARERHVAERLLMHLEEMQHTISTDEEKSAAVVNAIGLYMRHLGVR-------TKSGDKKSGRNFFRKKV----------------------------------------------------------------------------------------MGNRRSDEPAKTKKGLSSILDAARWN--------RGEPQ------------VPDFR-----------HLKAEVDAEKPGATDRKGG---VGMPSRDRNIGAPGQDTPGVS---------------------------------------LHPLSLDSPD-REPGADAPLEL---GDSSPQGPMSLESLAPPE----STDEGAETESPEPGDEGEPGRSGLELEP------------------------------------------------------------------EEPPGWRELVPPDTLHSLPKSQVKRQEVISELLVTEAAHVRMLRVLHDLFFQPMAECLFFPLEELQNIFP-SLDELIEVHSLFLDRLMKRRQESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKDPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQN-----TEEPTEREKVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLSHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKDKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTS-AMTREVATDHKAFYVLFTWDQEAQIYELVAQTVSERKNWCALITETAGSLKVPAP---------------------------------------------------------------------------------------------ASRPKPRPSPS------------STREPLLSSSENGNGGRETSP------------------------------------------------------------------ADARTERILS--------------DLLPFC-------------------------RPGPEGQLAATALRKVLSLKQLLFPAE----------EDNGAGP-PRDGDG----VPGGGPLSPARTQEIQENLLSLEETMK--------QLEELEEEFCRLRP------LLSQLG-------GNSVP---------QPGCT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P7X5-1", "uniprot_id": "A0A8M9P7X5_DANRE", "id": "A0A8M9P7X5-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLFSILVGARFAGVGRTCDSMDYEDAH----------NGRGLSGAQGLNPVMNIIGAEDEDFENDEQPMVDDQCIHFNSIELLKSRPTHLLVFLHHVMLQFDCAPVLCYLHADLMKNLNTKDTKKHFGEFYNTFLEKGAILKVSVP-SNIAPEID-RLRPELINEEQQKRYANEIQFAQSPEILRQLEDFRQKRMMGMTPNERELNDVESHRPTDRIPMDMKEKAVAESLLEKMVEANPSIVPDKDKSNSIFGAVAYYMKYLGVK-------TRAFDNKKSKSGWRPSVPSMLKPWSVN---------------------------------------------------------KQIKPVKPPGIGYDGKQSRLDFEAKQNKQPPHRVSVSDSVTPPGRKTGITVSGSTHGSESSEELPISVSVTPSPDFQTDTVGIINNRTDPKPASEGGEVSPVSTGGT---VSICEPLAVIDVPPEDIQDSGRKKPR------------------------------NVRRSESLCVERRHSRRGGSTRAKQSRSRSDVDLQSTSTSHPLSPSPQHSVSVEGDKTPEIALLTPTFVPAPQQEEIEPRL------------------------------------------------------------LELEQDPLNWRELASSESLHKLSKKEAKRQEVINELFVTEQAHVRMLSVLQTVFSRPLEKQEYMTANEVATIFS-SLDDIIEMHYVFYENLKKLREEDEYIVKTISTPLLNRFSGSEGEWFQKLTARFCSYQSWALEQIKSRQKKDPRFNAFILEAESKPQCRRLQLKDIIPIEMQRLTKYPLLLENIAKN-----TEDATEKEKINQAAESCRKILNHVNEEVKQMENLLILKDYQRRLDTSGLKPSNE-LYSEYKTIDLTNRTMLFEGPLTWRVTKEKAIDVHCVLLSDLLVLFQKQDDKMLLKCQSKSNIAVQEGKQMLSPIIKLES-VFLREVATDPKALYVIFTWDSGAQIYELVAQSVGERKNWTEAIKSAVDELKKASK---------------------------------------------------------------------------------------------SNTKLERNSRAGSVPNNIAVPLYGPAHPPLSPTENG-GELLKNR------------------------------------------------------------------VGRFSEKIRESDPPLIDYLAANGFDLLTHS-------------------------HTPPE-KSATVALDEVMCLKRLLVGSISLSDDAQTLGENGGMAPESQDADGTQLSVEESSTEAGPEVEEHEEDVENKGEEEKGISAPLVLSEERMEEVQMRLQA------LEEQLKRLRLVEEDHYKLQEALAKYTLQGGHYN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAN6-1", "uniprot_id": "A1ZAN6_DROME", "id": "A1ZAN6-1", "name": "", "aln": "MDDPSIKKRLLDLYTDEHEYDEVQEIPEESSIQPPETSTSHTSTNGSSHSGPGTATGPGATSAGPSAGAPQSPVIVVDSVPELPAPKQKSVKNSKSKQKQKQLANKSKIPRSPSLASSLSSLASSLSGHRDRDKDRDKDRENQNAVPPQTPPLPPSYKQNQMNGDSTAAAGGGVSAPATPTTANNNNASHNNGSIMGGGVQLNQSDNSNPVLQAPGERSSLNLTPLSRDLSGGHTQESTTPATTPSTPSLALPKNFQYLTLTVRKDSNGYGMKVSGDNPVFVESVKPGGAAEIAGLVAGDMILRVNGHEVRLEKHPTVVGLIKASTTVELAVKRSQKLTRPSSVSVVTPSTPILSGRDRTASITGPQPVDSIKRREMETYKIQTLQKMLEQEKLNLERLKSDQNNPSYKLSEANIRKLREQLHQVGAEDAPTVKLQAAAGNKNTALLTPNQIQHLSASATHSNQQFHHLHHHHNLHNNNYPPQQQPASTSPAFLSLLPRSLSSLSLGTRKNKTEKDLTTSSPFGLTTDFLQQQRMSHQAESMSQSMHQHTSTPTSQQFFHPHQQQHRFKETGPTSKGKNKFLISRSLIEEDVPPPLPQRNPPRQLNLDLKNGNASPGGSHLVAPVSDLDRATSPQLNRSQQQQLPSSTDNSPSNAKSKRSKIKTKALSDPKMSTQMFLQMESASAAGAAGGSIEVDGGPPPLPPRLPGMMTEDMSRGSCQNLAQPNSVGTAFNYPLVSTTTAVQNDNLNIAFPLSQRPNIVQQLQQYQQQQQHQMSGGQATGALGQTPNLGKNKHRRVGSSPDNMHPRHPDRITKTTSGSWEIVEKDGESSPPGTPPPPYLSSSHMTVLEDPNENNRGAAAAGPGVFIESHQFTPMAGASSPIPISLHSSHMHAAQSNDTQKEIISMEDENSDLDEPFIDENGPFNNLTRLLEAENVTFLAIFLNYVISNSDPAPLLFYLITELYKEGTSKDMRKWAYEIHSTFLVPRAPLSWYRQDESLAREVDNVLQLEYDKVEILRTVFLRSRKRAKDLISEQLREFQQKRTAGLGTIYGPTDDKLAEAKTDKLREQIIDKYLMPNLHALIEDENGSPPEDVRKVALCSALSTVIYRIFNTRPPPSSIVERVHHFVSRDKSFKSRIMGKNRKMNVRGHPLVLRQYYEVTHCNHCQTIIWGVSPQGYHCTDCKLNIHRQCSKVVDESCPGPLPQAKRLAHNDKISKFMGKIRPRTSDVIGNEKRSRQDEELDVELTPDRGQASIVRQPSDRRPDAN---ISIRSNGNTSCNTSGLNTTDLQSSFHGSCANDSINPGGGAGCNMDLSTSVASTTPSTSGSVAAGLSAFAELNALDTVDKEARRERYSQHPKHKSAPVSVNRSESYKERLSNKRNRNSRRKTSDPSLSSRPNDEQLDLGLSNATYVGSSNSSLSSAGGSESPSTSMEHFAAPGAAGGVQVPPMGLNQNQHPHLLIQQHAQQYCQQDSFQAGLAGAAGSSAASNSSFWNAGHPLPVARWTLESEDEDDVNEADWSSMVAAEVLAALTDAEKKRQEIINEIYQTERNHVRTLKLLDRLFFLPLYESGLLSQDHLLLLFPPALLSLREIHGAFEQSLKQRRIEHNHVVNTIGDLLADMFDGQSGVVLCEFAAQFCARQQIALEALKEKRNKDEMLQKLLKKSESHKACRRLELKDLLPTVLQRLTKYPLLFENLYKVTVRLLPENTTEAEAIQRAVESSKRILVEVNQAVKTAEDAHKLQNIQRKLDRSSYD------KEEFKKLDLTQHHLIHDG--NLTIKKNPSVQLHGLLFENMIVLLTKQDDKYYLKN---LHTPLSITNKPVSPIMSIDADTLIRQEAADKNSFFLIK--MKTSQMLELRAPSSSECKTWFKHFSDVAARQSKNRSKNASSNHDTSISDPALAAIPHSNTKESLELSTDTVQPLAATATLTTTPLAPMLPIATVTPAPATNNSNVSSLTGVQLRNPQRDATASESDADYVNTPKPRSSQNEVN---RTMSIRSTGEPIQKYSANGTEANDVTLRHSQSTRESVRPGSTGEERNSTYGMVGGNSKRDSASIVCSNNSNNTRTLLMQSPLVDPTAIQVSISPAHTAEPVLTPGEKLRRLDASIRNDLLEKQKIICDIFRLPVEHYDQIVDIAMMPEAPKDSADIALAAYDQIQTLTKMLNEYMHVTPEQEVSAVSTAVCGHCHEKEKLRKKVAPSSSFSSSPPPLPPPNRQHAQAQAQIPPSRLMPKLQTLDLDEVAIHEDDDGYCEIDELRLPAIPSKPHERPTTPLAPFNTEPKTSQSVIDASKRQSTDAVPEGLLEQEPLEGDKTETKGEDNEVKTVPSDKLSESCNEERQCVEADITKEVADPTTSKNEAAASVDELPSQSREIKTAENASKSVADKKEDNEETIEEGVASTVDSSTQTSPTESPKETDKLTGGSSSTCGPNRIQHASVLEPSVPCHALSSIVTILNEQISMLLPKINERDMERERLRKENQHLRELLSALHDRQRVDEVKETPFDLKKLMHAEDVEFDDDIDAISNSSLTPTPTPIPTASPSASGQVETAEAMRITSTEDEE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** .* . . **. ***: : : :: : : . :.* :*::* : : .*:* * ::: . .*: :* ::: :** * * .:* *:* : : . : : . . : .**.:*:.** *: . . *: : :: : * : : : : * * : :..: : . . . :: : ..: .: . . . * . .. . : . .. . * :. ... . . . . *. . . . .* : : . . * . . . *. * : .* .:...: * *.. : ****:*.*: ** *** * :*. :* *: . :. :.: :*. :* .: *:* * : * : * * :::: *. * *.* .* : :::::**: *. *** :* ::.*: : :: ::**: ****:***::* :*********::.: : .*:.:* :: *.*..:.** .**: *: *: *:: **:** : .*:*.:*:*:: ::.:* . :.*: ::::* :*:.::::*: :**: . . : : *:: : : .: *: *:* :::::: . :*: ** * : .* *.* :.... . . * * . .* . : ** :* : *** . . . * .* :: *.::* . . :: : * . . . : : . : :: :: .:* : ", "identical_positions": 150, "similar_positions": 292, "identity": "5.82%" }, { "cls_id": "homologset.agr.RGD:620952", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923S2-1", "uniprot_id": "PDZ1I_RAT", "id": "Q923S2-1", "name": "PDZK1-interacting protein 1", "aln": "-MLALSLLALGLLAEVAPASCQQGLGNLQP-WMQGLIAVAVFLVLVAIAFAVNHFWCQEEQEPGSTMMITGNKADGVLVGMDGRYSSMASGFRSSEHKNAFENVLEEEGRVRSTPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQH0-1", "uniprot_id": "PDZ1I_MOUSE", "id": "Q9CQH0-1", "name": "PDZK1-interacting protein 1", "aln": "-MLAFSLLVLGLLAEVAPASCQQGLGNLQP-WMQGLIAVAVFLVLVAIVFAVNHFWCQEEPEPGSTVMIIGNKADGVLVGMDGRYSSMASGFRSSEHKNAYENVLEEEGRVRSTPM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13113-1", "uniprot_id": "PDZ1I_HUMAN", "id": "Q13113-1", "name": "PDZK1-interacting protein 1", "aln": "-MSALSLLILGLLTAVPPASCQQGLGNLQP-WMQGLIAVAVFLVLVAIAFAVNHFWCQEEPEPAHMILTVGNKADGVLVGTDGRYSSMAASFRSSEHENAYENVPEEEGKVRSTPM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90X36-1", "uniprot_id": "Q90X36_DANRE", "id": "Q90X36-1", "name": "", "aln": "MGKPVSVFYWFLLTLGLVAAQAETAGRALPNWLTGIIAVAVFLFLVFISFLVNKAWCNNPSQPEAVIPNAYAMTNGSSI-----HETSLDAVRSGDGPNMYENVIVHQTEEKVTAM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*:: **: *: : *. * *: *:*******.** * * **: **:: :* : ::* : :.: ..**.: * :*** .: . : *.*", "identical_positions": 33, "similar_positions": 32, "identity": "28.45%" }, { "cls_id": "homologset.agr.RGD:620953", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63398-1", "uniprot_id": "COE1_RAT", "id": "Q63398-1", "name": "Transcription factor COE1", "aln": "-----------------MFGIQESIQRSGSSMKEEPLGSGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSE----------------------------AAT-PCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEAS-QATNQGFTRN-SSSVSPHG-YVPSTTPQQTNYNSVTTSMNGYGSAAMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQ--------------AISGMIVPPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UH73-1", "uniprot_id": "COE1_HUMAN", "id": "Q9UH73-1", "name": "Transcription factor COE1", "aln": "-----------------MFGIQESIQRSGSSMKEEPLGSGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTPSY---------------------LEHAT-PCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEAS-QATNQGFTRN-SSSVSPHG-YVPSTTPQQTNYNSVTTSMNGYGSAAMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQ--------------AISGMIVPPM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07802-1", "uniprot_id": "COE1_MOUSE", "id": "Q07802-1", "name": "Transcription factor COE1", "aln": "-----------------MFGIQESIQRSGSSMKEEPLGSGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTPSY---------------------LEHAT-PCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEAS-QATNQGFTRN-SSSVSPHG-YVPSTTPQQTNYNSVTTSMNGYGSAAMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQ--------------AISGMIVPPM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B8M6-1", "uniprot_id": "A0A8M2B8M6_DANRE", "id": "A0A8M2B8M6-1", "name": "Transcription factor COE4", "aln": "-----------------MFGIQESIQRCGSILKEEPIGAGMNTVRTWIQGAGVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTSFVGFVEKEKETTGEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQPIIYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVSVEGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTPSY---------------------LEHAAAPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGSMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVESLYGMPHNNQEIILKRAADIAEALYNVPRSHNQLTGLTNSSVHTSMMGGNSFTGQLAVNVSESS-QGGNQGFGRN-TSSVSPHG-YVPSSTPQQSSYSTVSTSMNGYGNSGMTNLTGSPNFLNGSAANSPYAIVPSSPTMASSTSLPSNCINSSGIFSFSPANMVSAVKQKSAFAPVIRPQSSPPPTCTSTNGNGVQDQSFVDSNKYSTASALQGLAFS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IWI1-1", "uniprot_id": "COE1A_DANRE", "id": "A0A0R4IWI1-1", "name": "Transcription factor COE1-A", "aln": "-----------------MFGIQDSIQRSGSSMKEEPIGAGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTSFVGFVEKEKESTGEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIIYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVSVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTPSY---------------------LEHAT-PCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYT-ALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYNVPRGHNQLPGLTNSSVHSGMMGVNSFHSQLAVNVSDST-QAANQGFSRN-TSSVSPHG-YVPSTTPQQSSYSTVSTSMNGYGNAGMTTLGGSPNFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQASPPPTCTSANGNGLQ--------------VIPGMIVPPM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P56721-1", "uniprot_id": "COLL_DROME", "id": "P56721-1", "name": "Transcription factor collier", "aln": "MEWGRKLYPSAVSGPRSAGGLMFGLPPTAAVDMNQPRGP-MTSLKEEPLGSRWAMQPVVDQSNLGIGRAHFEKQPPSNLRKSNFFHFVIALYDRAGQPIEIERTAFIGFIEKDSESDATKTNNGIQYRLQLLYANGARQEQDIFVRLIDSVTKQAIIYEGQDKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVISTQVAVDGPLLAISDNMFVHNNSKHGRRAKRLDTTEGTGNTSLSISGHPLAPDSTYDGLYPPLPVAT-PCIKAISPSEGWTTGGATVIIVGDNFFDGLQVVFGTMLVWSELITSHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGSPGRFVYVSALNEPTIDYGFQRLQKLIPRHPGDPEKLQKEIILKRAADLVEALYSMPRS----------------------------------PGGSTGFNSYAGQLAVSVQDGSGQWTEDDYQRAQSSSVSPRGGYCSSASTPHS-------SGGSYGATAAS----------AAVAATANGYAP-APNMGTLSSSPGSVFNSTSMSAVSSTWHQAFVQHH--HAATAHPHHHYPHPHQPWHNPAVS--------------AATAAAV---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .: .: ::* *. *.::: *: .. **.:*:.*********************:***** ***:*****:*:**:**:.*: . ******:*******:** * ***::******:***.*:******************:*******************************************************:** * *:* :**:****************:***.:* *: *********************:**********:**:*********.******************************:****:*. ****************:*********:* **:**********:**.**:. . * **: .****.*.:.: * ::.: * :*****:* * .*::. :: * ..** :. : .:.* :. . .* :*.*.: :* *.. .*:.: :.*.: : *::: .*.. :*: * . . :. .:. . . . ", "identical_positions": 330, "similar_positions": 124, "identity": "50.93%" }, { "cls_id": "homologset.agr.RGD:620954", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99NI4-1", "uniprot_id": "IPMK_RAT", "id": "Q99NI4-1", "name": "Inositol polyphosphate multikinase", "aln": "MAAEPP-ALRLRPPG-----------STGDSPPVP-----RLLGGCVPLSHQVAGHMYGK---DKVGILQHP-DGTVLKQLQPPPRGPRELEFYTMVYAADCA--DAVLLELRKHLPKYYGVWSPPSAP-NDVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASAEKIQQQVSKYPLMEEIG------FLVLGMRVYHLHSDSYETQNQHYGRGLTKETLKEGVSKFFHNGFCLRKD-------AVAASIQKVEKILQWFENQKQLNFYASSLLFVYEGSSQPATTKSNDRTLAGRFLSKGALSDADVLECNNNFHLFSSPANG---TSVGKSLSKAYSRHRKLYAKKHQSQTSLKVETLEQDNGWKSMSQEHLNGNVLSQLEKVFYHLPAGRQEIAEAEVRMIDFAHVFPSNT--VDEGYVYGLKHLIAVLRSILDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TT16-1", "uniprot_id": "IPMK_MOUSE", "id": "Q7TT16-1", "name": "Inositol polyphosphate multikinase", "aln": "MAAEPP-ALRLRPPG-----------STGDSPPVP-----RLLGGCVPLSHQVAGHMYGK---DKVGILQHP-DGTVLKQLQPPPRGPRELEFYTMVYAADCA--DAVLLELRKHLPKYYGVWSPPTAP-NDVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASSEKIQQQVSKYPLMEEIG------FLVLGMRVYHLHSDSYETQNQHYGRGLTKETLKEGVSKFFHNGFCLRKD-------AIAASIQKVEKILQWFENQKQLNFYASSLLFVYEGSSQPATTKANDRTLAGRFLSKGPLTDADGLECNNNFHLFGAPPNG---MSVGKSLSKAYSRHRKLYAKKHQSQTSLKVETLEQDNGWRSMSQEHLNGNVLAQLEKVFYHLPAGRPEIPEAEVRMIDFAHVFPSNT--VDEGYVYGLKHLIAVLRSILDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFU5-1", "uniprot_id": "IPMK_HUMAN", "id": "Q8NFU5-1", "name": "Inositol polyphosphate multikinase", "aln": "MATEPPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGRLRFLNGCVPLSHQVAGHMYGK---DKVGILQHP-DGTVLKQLQPPPRGPRELEFYNMVYAADCF--DGVLLELRKYLPKYYGIWSPPTAP-NDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEEIG------FLVLGMRVYHVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKD-------AVAASIQKIEKILQWFENQKQLNFYASSLLFVYEGSSQPTTTKLNDRTLAEKFLSKGQLSDTEVLEYNNNFHVLSSTANGKIESSVGKSLSKMYARHRKIYTKKHHSQTSLKVENLEQDNGWKSMSQEHLNGNVLSQLEKVFYHLPTGCQEIAEVEVRMIDFAHVFPSNT--IDEGYVYGLKHLISVLRSILDN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QAF7-1", "uniprot_id": "A0A8M9QAF7_DANRE", "id": "A0A8M9QAF7-1", "name": "Kinase", "aln": "MSADGQIVSKFTLVQLEN--------GNHNHESVK----QRLLDGCVPFSHQVAGHKCGI---NNTGVLKHP-DGTILKQLQPPPRGPREMHFYTQVYAKDCT--DTRLLELQQHLPKFYGTWSPRESP-HELYLKLEDVTRRFLRPCIMDVKIGRRSYDPFASKEKREEQISKYPLMEEIG------FLLLGMRVYQINSDSYITHDQFYGRSLGKDTIKNGLSRFFHNGQDLRRG-------AISLIISKIRRILRWFETQTQLHFYASSLLLVYEGSPHTLDGQKHKQTQHR-------------------------PQNN---------------------SSSHQSRSALTQN----TNGTLGGAGGEDDGDVGVEDKMQFGQE-------EAVEVRMIDFAHVFPSDT--ADQSYMYGLRNLLAALELILKE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPR6-1", "uniprot_id": "Q9VPR6_DROME", "id": "Q9VPR6-1", "name": "Kinase", "aln": "MAKSDQ----------------------------------ELPEGFRQLKTQVAGHTFEESNAEAVGLLQDSKAGCVLKPLGKPECGERELRFYESLAEAGASGDNDLLALLRGHVPRFYGPLKLVVNRRERTFLRLEDLTRSYAKPCVMDVKMGKRTWDPESSPNKRKVEEAKYVMCKQKLGLCLPGFQVYLPKEEHTQETTILRHGKDYGKSLNVEGFKQTMALFFNASTSDSKSRRAGCELLLKEVLRQLQEILAWFQRQRLLHFYASSLLICYDYSRLADPPKP-------------------------------------------------------------------------LINGYHQNDDDP----------------------ATWVRVKMIDFAHVYPAEQGLPDENYMFGLQSLIEVVQSILHR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . .: * :. ***** : .*:*:.. * :** * * * **:.** : .. : * *: ::*::** . . :*:***:*: : :**:****:*::::** :* :* : : :** : :: * : : : :. : ..: **:.* : :*: :: **: . :. : : ::..** **: * *:*******: *: * . : ** ..*:*******:*:: *:.*::**: *: .:. **. ", "identical_positions": 82, "similar_positions": 94, "identity": "18.72%" }, { "cls_id": "homologset.agr.RGD:620955", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48450-1", "uniprot_id": "LSS_RAT", "id": "P48450-1", "name": "Lanosterol synthase", "aln": "MTEGTCLRRRGGPYKTEPATDLTRWRLHN-ELGRQRWTYYQAEEDPGREQTGLEAHSLG----LDTTSYFKNLPKAQTAHEGALNGVTFYAKLQAED-GHWAGDYGGPLFLLPGLLITCHIAHIPLPAGYREEMVRYLRSVQLP-DGGWGLHIEDKSTVFGTALSYVSLRILGIGPDDPDLVRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGINTLFPEMWLLPEWFPAHPSTLWCHCRQVYLPMSYCYATRLSASEDPLVQSLRQELYVEDYASIDWPAQKNNVCPDDMYTPHSWLLHVVYGLLNLYERFHS-TSLRKWAIQLLYEHVAADDRFTKCISIGPISKTVNMLIRWSVDGPSSPAFQEHVSRIKDYLWLGLDGMKMQGTNGSQTWDTSFAVQALLEAGAHRRPEFLPCLQKAHEFLRLSQVPDNNPDYQKYYRHMHKGGFPFSTLDCGWIVADCTAEALKAVLLLQER--CPSITEHVPRERLYDAVAVLLSMRNSD----GGFATYETKRGGYLLELLNPSEVFGDIMIDYTYVECTSAVMQALRHFREYFPDHRATESRETLNQGLDFCRKKQRADGSWEGSWGVCFTYGTWFGLEAFACMGHIYQNRTACAEVAQACHFLLSRQMADGGWGEDFESCEQRRYVQSAGSQVHSTCWALLGLMAVRHPDISAQERGIRCLLGKQLPNGDWPQENISGVFNKSCAISYTNYRNIFPIWALGRFSSLYPDNTLAGHI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLN5-1", "uniprot_id": "LSS_MOUSE", "id": "Q8BLN5-1", "name": "Lanosterol synthase", "aln": "MTEGTCLRRRGGPYKTEPATDLTRWRLQN-ELGRQRWTYYQAEDDPGREQTGLEAHSLG----LDTRSYFTDLPKAQTAHEGALNGVTFYAKLQAED-GHWAGDYGGPLFLLPGLLITCHISHISLPAGYREEMVRYLRSVQLP-DGGWGLHIEDKSTVFGTALNYVALRILGIGPDDPDLVRARNVLHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPEWVPAHPSTLWCHCRQVYLPMSYCYATRLSASEDPLVQSLRQELYVQDYASIDWPAQRNNVSPDEMYTPHSWLLHVVYGLLNLYERFHS-TSLRKWAVQMLYEHIAADDCFTKCISIGPISKTINMLVRWSVDGPSSPAFQEHVSRIKDYLWLGLDGMKMQGTNGSQIWDTSFAIQALLEAGAHHRPEFLPCLQKAHEFLRLSQVPENCPDYQKYYRHMRKGGFSFSTLDCGWIVADCTAEGLKAVLLLQNQ--CPSITEHIPRERLCDAVDVLLSLRNAD----GGFATYEKKRGGYLLELLNPSEVFGDIMIDYTYVECTSAVMQALKHFHEHFPDYRAAEVRETLNQGLDFCRRKQRADGSWEGSWGVCFTYGTWFGLEAFACMGHTYQDGAACAEVAQACNFLLSQQMADGGWGEDFESCEQRRYVQSARSQVHSTCWALMGLMAVRHPDITAQERGIRCLLGKQLPNGDWPQENISGVFNKSCAISYTSYRNIFPIWALGRFSNLYPDNTLAGHI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48449-1", "uniprot_id": "LSS_HUMAN", "id": "P48449-1", "name": "Lanosterol synthase", "aln": "MTEGTCLRRRGGPYKTEPATDLGRWRLNC-ERGRQTWTYLQDER-AGREQTGLEAYALG----LDTKNYFKDLPKAHTAFEGALNGMTFYVGLQAED-GHWTGDYGGPLFLLPGLLITCHVARIPLPAGYREEIVRYLRSVQLP-DGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPMSYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALLNLYEHHHS-AHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQEHVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRLSQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEK--CPHVTEHIPRERLCDAVAVLLNMRNPD----GGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFSQLYPERALAGHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38604-1", "uniprot_id": "ERG7_YEAST", "id": "P38604-1", "name": "Lanosterol synthase ERG7", "aln": "MTEFYSDTIG------LPKTDPRLWRLRTDELGRESWEYLTPQQAANDPPSTFTQWLLQDPKFPQPHPERNKHSPDFSAFDACHNGASFFKLLQEPDSGIFPCQYKGPMFMTIGYVAVNYIAGIEIPEHERIELIRYIVNTAHPVDGGWGLHSVDKSTVFGTVLNYVILRLLGLPKDHPVCAKARSTLLRLGGAIGSPHWGKIWLSALNLYKWEGVNPAPPETWLLPYSLPMHPGRWWVHTRGVYIPVSYLSLVKFSCPMTPLLEELRNEIYTKPFDKINFSKNRNTVCGVDLYYPHSTTLNIANSLVVFYEKYLRNRFIYSLSKKKVYDLIKTELQNTDSLCIAPVNQAFCALVTLIEEGVDSEAFQRLQYRFKDALFHGPQGMTIMGTNGVQTWDCAFAIQYFFVAGLAERPEFYNTIVSAYKFLCHAQFDTEC--VPGSYRDKRKGAWGFSTKTQGYTVADCTAEAIKAIIMVKNSPVFSEVHHMISSERLFEGIDVLLNLQNIGSFEYGSFATYEKIKAPLAMETLNPAEVFGNIMVEYPYVECTDSSVLGLTYFHKYF-DYRKEEIRTRIRIAIEFIKKSQLPDGSWYGSWGICFTYAGMFALEALHTVGETYEN---SSTVRKGCDFLVSKQMKDGGWGESMKSSELHSYVDSEKSLVVQTAWALIALLFAEYPNKEVIDRGIDLLKNRQEESGEWKFESVEGVFNHSCAIEYPSYRFLFPIKALGMYSRAYETHTL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** . * ** ***. * **: * * : .. : : * :. .. . :*.:.. ** :*: ** * * :. :* **:*: * : . ::: * :* * *::**: .. * ******* ********.*.** **:**: *.* .:**. * : ***:. * ***:**:.**:*.***:*. ** **:* * **. * * * **:*:** .::*.. **::.**:*:*.: : .*:: ::*.*. ::* *** *.:. .*: :**:. : . : : :*: : :: *..:.*.*:.::. *: :* * ***. *: * *: * :**.: **** * ** :**:* :: ** .**** : .*::** :*. : **. :**.: *** *: *:*****.:**:::::: . : . :. *** :.: ***.::* . *.*****. :. :* ***:****:**::*.*****.: : .* :*:: * ::* * * : .::* ::.* .**** ****:****. *.***: :*. *.: .: * :.*.**:*:** ******.::*.* : *::* * : .*.**::.*: ..:*: . :**: * :* .*:* *.: ****:****.*..** :*** *** :* * .:* ", "identical_positions": 269, "similar_positions": 229, "identity": "36.01%" }, { "cls_id": "homologset.agr.RGD:620956", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97608-1", "uniprot_id": "OPLA_RAT", "id": "P97608-1", "name": "5-oxoprolinase", "aln": "MGSPEGRFHFAIDRGGTFTDVFAQCPGGHV---RVLKLLSEDPANYADAPTEGIRRILEQEEGVLLPRGRPLDTSRIASIRMGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVLEVDERVVLYRG-------EPGAGSP---VKGRTGDLLEIQQPVDLEALRGKLEGLLSRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTACADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSATTYHLEGGQPVIGFDMGGTSTDVSRY-AGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLTNGPCP-------ASQLSLEEVAMGFVRVANEAMCRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSY-TPETFAQLDQRLSRLEEQCVDALQVQGFPRSQISTESFLHLRYQGTDCALMVSAHQHPATACS----PRAGDFGAAFVERYMREFGFIIPERPVVVDDVRVRGTGRSGLQLEDTPKIQTGP----------PHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVTDTGDIRISVGAEGPSMAD-----TRLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGQTRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALR-APGKISGCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAFGTSRQARGLPLEVSAEDHMDDGSPICLRVQINLSQGSAVFDFTGSGSEVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVRVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACSASQGCMNNVTLGN------------ARMGYYETVAGGAGAGP------GWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRP-GSGGRGRFRGGDGVVRELVFREEALLSVLTERRAFQPYGLHGGEPGARGLNLLIRK-DGRTVNLGGKTSVTVYPGDVFCLHTPGGGGYGDPEDP--APPPGSPPLFPAFPERGSVFEYRRAQEAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K010-1", "uniprot_id": "OPLA_MOUSE", "id": "Q8K010-1", "name": "5-oxoprolinase", "aln": "MGSPEERFHFAIDRGGTFTDVFAQCPGGHV---RVLKLLSEDPANYADAPTEGIRRILEQERGVLLPRGRPLDTSHIASIRMGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVVEVDERVLLYRG-------EPGAGSP---VKGCTGDLLEIQQPVDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTACADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSTTTYQLEGGQPVIGFDMGGTSTDVSRY-AGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLASGPCP-------ASQLSLEEVAMGFVRVANEAMCRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSY-TPETFAQLDQRLSRLEEQCVDALQAQGFSRSQISTESFLHLRYQGTDCALMVSANQHPATTCS----PRAGDFGAAFVERYMREFGFIIPERSVVVDDVRVRGTGRSGLQLEETSKIQSGP----------PHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIETGDIRISVGAEAPSMID-----TKLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGQSRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALQ-APGKISGCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAFGTSRQARGLPLEVSAKDHMDDGSPICLHVQINLNQGSAVFDFSGSGSEVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACAASQGCMNNVTLGN------------ARMGYYETVAGGAGAGP------GWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRP-GSGGRGRFRGGDGVVRELVFREEALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRK-DGRTVNLGGKTSVTVYPGDAFCLHTPGGGGYGDPEDP--APPPGSPPLYPAFPERGSVYEYRRAQEAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14841-1", "uniprot_id": "OPLA_HUMAN", "id": "O14841-1", "name": "5-oxoprolinase", "aln": "MGSPEGRFHFAIDRGGTFTDVFAQCPGGHV---RVLKLLSEDPANYADAPTEGIRRILEQEAGMLLPRDQPLDSSHIASIRMGTTVATNALLERKGERVALLVTRGFRDLLHIGTQARGDLFDLAVPMPEVLYEEVLEVDERVVLHRG-------EAGTGTP---VKGRTGDLLEVQQPVDLGALRGKLEGLLSRGIRSLAVVLMHSYTWAQHEQQVGVLARELGFTHVSLSSEAMPMVRIVPRGHTACADAYLTPAIQRYVQGFCRGFQGQLKDVQVLFMRSDGGLAPMDTFSGSSAVLSGPAGGVVGYSATTYQQEGGQPVIGFDMGGTSTDVSRY-AGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGENQPLSPEASRKALEAVATEVNSFLTNGPCP-------ASPLSLEEVAMGFVRVANEAMCRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLLY-APETFVQLDQRLSRLEEQCVDALQAQGFPRSQISTESFLHLRYQGTDCALMVSAHQHPATARS----PRAGDFGAAFVERYMREFGFVIPERPVVVDDVRVRGTGRSGLRLEDAPKAQTGP----------PRVDKMTQCYFEGGYQETPVYLLAELGYGHKLHGPCLIIDSNSTILVEPGCQAEVTKTGDICISVGAEVPGTVG-----PQLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGQTRPVFYVASRGHHADIGGITPGSMPPHSTMLQQEGAVFLSFKLVQGGVFQEEAVTEALR-APGKVPNCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAFGTSRQARGLPLEVSSEDHMDDGSPIRLRVQISLSQGSAVFDFSGTGPEVFGNLNAPRAVTLSALIYCLRCLVGRDIPLNQGCLAPVRVVIPRGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACAASQGCMNNVTLGN------------AHMGYYETVAGGAGAGP------SWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRR-GSGGRGRFRGGDGVTRELLFREEALLSVLTERRAFRPYGLHGGEPGARGLNLLIRK-NGRTVNLGGKTSVTVYPGDVFCLHTPGGGGYGDPEDP--APPPGSPPQALAFPEHGSVYEYRRAQEAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6Z6-1", "uniprot_id": "E7F6Z6_DANRE", "id": "E7F6Z6-1", "name": "", "aln": "MAETKGKFDFAIDRGGTFTDVFARLPDGRE---KVLKLLSHDPQNYKDAPTEGIRRVLEEETGKSFPRDQPVDTSQIGWIRMGTTVATNALLERQGERTALLVTSGFKDLLHIGTQARPNLFDLEVCMPDVLYEEVIEVEERVILRQDSC-----QLPRNEPKRIVTGSTGESLEVWRELDLQRVEQDLRRVQSKGIRSLAVLLLHSYTWAAHEKAVGSLAKRLGFAQVSLSSEVMPMVRAVPRGYTVCADAYLTPKIHLYLTKFTAGFKGGLKGVDVLFMQSDGGLTPMEQFCGSRAVLSGPAGGVVGYAVTCYKSTEKKPVIGFDMGGTSTDVSRY-AGQYEHVFEATIAGITLQAPQLDINTVAAGGGSRLFFRSGMFVVGPESAGAHPGPACYRKGGPLTVTDANLALGRLLPSFFPKIFGPGENEPLSTEETMKHFSKLTQEINHFLSTNQTSNSASGAQLSKMSIEDIAMGFINVANEAMCRPIRALTQAKGHDTSEHVLACFGGAGGQHACAIARALGMKMVFIHKYSGVLSAYGLALADVVEEVQEPCSLQY-EAGSFSELDRRIEQLSQRCDEILRKRGFSRSQINIEVFLHLRYEGTDCALMITATDHPSNASS----CRTGDFRTAFTKRYLKEFGFTITDRPIMVDDIRVRGSGKSGIRSEVQAKAGQKS----------PNPIKMTQCYFEDRYLDTSVYLWEDLSCDHSIQGPAIIIDKNSTILVEPTCVAHLTEDGDVCIAVGMGTQCVLG-----TELNTIQLSIFSHRFMSIAEQMGRVLQRTAISTNIKERLDFSCAVFGPDGGLVSNAPHIPVHLGAMQETVQFQIKAAGGSLKEGDVILSNHPCAGGSHLPDLTVITPVFRDGVSAPVFFVASRGHHADIGGITPGSMPPHSTSLQQEGAVFTSFKLVTGGIFQEKAVTEALM-APAQYPGCSGTRNLRDNLSDLRAQVAANQRGCQLVGELITSYGLDVVQAYMGHIQSNAELAVRDMLKDFAHRQREKTGSLEVEAEDQMDDGTLIRLKVQINEEQGSAVFDFTGTGTEVWGNCNAPRAITLSALIYCLRCMVGQDIPLNQGCLAPVKVIIPPGSILQPSQNAAVVGGNVLTSQRVVDVIFKAFQVCAASQGCMNNVSFGC------------EKSGYYETVAGGAGAGP------SWNGRGGIHTHMTNTRITDPEILESRYPVILEQFSLRP-DSGGAGLYRGGDGVIRKLRFRSPVVLSVLTERRSTKPYGLHGGKNGAPGLNLLHKT-DGRVLNLGAKTTISLDPGDMFSLFTPGGGGYGRMDEL--DGDHHLPSKRRCLHE---------SQNKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W247-1", "uniprot_id": "Q9W247_DROME", "id": "Q9W247-1", "name": "5-oxoprolinase", "aln": "MSGT--KYCFAIDRGGTFTDVLCICPNGKV---RTMKLLSEDPERYSDAPREGIRRILKEETGEDLAASGLVDTSKIGWVRMGTTVATNALLERKGDPVVLVVNSGFRDLLYIGNQARPKIFDLNIRKPANLYKSVVEVDCRIVPKQAD------RCELNHSWKELEGVAGTKYLEVRPVDEVAVRQALSDARDQGVSSVSVVLAHSYACPEHELRVGAIARELGFSHVTLSHQAMPMCRVVARGYTACAEAYLTPHVDRYLASFKSGFDKQLEGVDVLFMQSDGGLTNMENFRGARAILSGPAGGVVGYALTGAR-ETELPLIGFDMGGTSTDVSRY-AGTYEHVIESTTAGVTIQAPQLDINTVAAGGGSRLFFRSGIFVVGPESAGSHPGPACYKKGGPLTVTDANLILGRILPQYFPKIFGPQENEPLDHEIARSKFVELQAEINNYLKSSGDN--------RVLSVEDVALGFIRVANETMCRPIRALTQSRGLDTANHVLSCFGGAGGQHACSIARNLGIAKVVVHKYAGILSAYGMALADVVQEFQEPNGLEF-SDANAQQLKERLDALSKQCQDKLSEQGFKR--IELEPFLHLRYEGTDGALMVAPSTGKQSSDSNPLLAAYGDFHATFLERYRTEFGFVLQNRRIIVDDIRIRGLGKNETPPESKVQAAAEAK---------PPAEANTRLYFDQGAFDSPIYLTKNLLAGHRITGPAVLIDQLSTIVVEPECGIQVTQFGDLIMDVKTGGKHGIN-----ADLDPVHLSIFSHRFMSIAEQMGRVLQRTSISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQYQLRVRGETLKNGDVILANHPSAGGSHLPDLTVITPVFYETHPRPVFFVASRGHHADIGGITPGSMPPHSTSLAQEGAAFKSFLIVENGLFQEQQIIEQLT-TPTAAKGAVGTRNLSDNLSDLKAQIAANHKGIQLVAELIGSYGLDVVQAYMSHIQKNAELAVRDMLRQIGRDTLERTGSTVLEAKEFMDDGSPIALKVTIDAEQGSALCDFTGSGVEVWGNCNAPRAITLSALIYCLRCMVGHDVPLNQGCLAPIQVIIPKNSILDPSEGAAVVGGNVQTSQRIVDTVLKAFGVCAASQGCMNNITIGD------------ESWGYYETVAGGAGAGP------GWHGAGGVHTHMTNTRITDPEILELRYPMILKRFCLRTDGSGGRGQFHGGEGVERDLLFRKPVTLSVLTERRTLQPYGLAGGESGKSGRNLVVKR-DGRVIALAGKTCIDVEAGDTFAMKTPGGGGYGPIEDFSKSGESLNQETSKRYVERGTVFNYLQCQESA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28273-1", "uniprot_id": "OPLA_YEAST", "id": "P28273-1", "name": "5-oxoprolinase", "aln": "--MQKGNIRIAIDKGGTFTDCVGNIGTGKQEHDTVIKLLSVDPKNYPDAPLEGIRRLLEVLEHKTIPRGIPLDISNVRSLRMGTTLATNCALERNGERCAFITTKGFKDSLLIGDQTRPDIFNLNIKKVVPLYDTVVEIDERVTLEDFSEDPYFTKSSPNEQEGILEGNSGEMVRVIKKPDESSVRSILKVLYASGIKSIAIAFLHSYTFPDHERIVGNIAREIGFSHVSLSSEVSPMIKFLPRAHSSVADAYLTPVIKKYLNSISAGLS-HAEDTHIQFMQSDGGLVDGGKFSGLKSILSGPAGGVIGYSSTCYDKNNNIPLIGFDMGGTSTDVSRYGDGRLEHVFETVTAGIIIQSPQLDIHTVAAGGSSILSWKNGLFRVGPDSAAADPGPAAYRKGGPLTITDANLFLGRLVPEFFPKIFGPNEDESLDLETTTLKFRELTDVINKDLN-------------SNLTMEEVAYGFIKVANECMARPVRAITEAKGHVVSQHRLVSFGGAGGQHAIAVADSLGIDTVLIHRYSSILSAYGIFLADVIEENQEPCSFILGEPETILKVKKRFLELSKNSIKNLLSQSFSREDIVLERYLNLRYEGTETSLMILQKYDDQ-----------WNFREWFSEAHKKEFGFSFDDKRIIIDDIRIRAIGKSGVRKEKTVDEQLIEISHFKKADVSKDASFTQKAYFDNKWVDTAVFKIDDLPAGTIIEGPAILADGTQTNIILPNSQATILN-SHIFIKINQKAAKTLSKSGYELDIDPILLSIFSHRFMDIALQMGTQLRKTSVSTNVKERLDFSCALFDSKGNLVANAPHVPVHLGSMSTCISAQAKLWEGKLKPGDVLITNHPDIGGTHLPDITVITPSFSSTG-ELIFYVASRAHHADIGGILPGSVPPNSKELYEEGTAIYSELVVKEGIFQEELIYKLFVEDPGKYPGCSGSRRFSDNISDLKAQVAANTKGIQLIGSLTKEYDLATILKYMAAIQTNASESIKKMLAKM----VEHFGTTKFSGEDRLDDGSLIKLQVIIRPEKEEYIFNFDGTSPQVYGNLNAPEAITNSAILYCLRCLVGEDIPLNQGCLKPLTIKIPAGSLLSPRSGAAVVGGNVLTSQRVTDVILKTFNVMADSQGDCNNFTFGTGGNSGNKTDKQIKGFGYYETICGGSGAGADSWRGSGWNGSDAVHTNMTNTRMTDTEVFERRYPVLLKEFSIRR-GSGGKGKYTGGNGVVRDVQFRKAVTASILSERRVIGPHGIKGGQDGSRGENLWVRHSTGALINVGGKNTIYAQPGDRFIIKTPGGGGFGQYKD--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :***:****** . *: .:**** ** .* *** *****:*: :. . :* *.: :*****:***. ***:*: .::.. **:* * ** *:* .:*:* : **. *:*:: *: . . : * :* : * :. * *: *::: : ***: . ** ** :*:.:**::*:** :. ** : :.*.:: *:***** :. *: : *:. :...: **:*****. * * ::********:**: * *:*************** * ***:*: **: :*:*****:******.* * ::.*:* ***:**.:.****.*:****:*:***** ***::* ** **** *::.*. * : : : :* * :::*::* **:.**** *.**:**:*:::* : * * .********* ::* **: * :*:::.:*** *: ****:.* *** .: . ::..*: *.:.. . * :.* * * * :*:***:**: :**: :* * : : **** : :: :::**:*:*. *:. * . : **: ::.:: :* . : **.:: * .* :: * . : . ..: : : . ::.: *********.** *** *::*::***:*********:*...*.**:****:*****:*. :. * : *: ***:::*** **:****:***** * :*:****.******** ***:**:*. * :**:.: * :* *:***: : : : * .. *:*.: **:***:**:*** :* **:..* .*.* .: **. ** **. :::.** : : . ...:: :***: * *:* * .: . : :* *:. :*:** ***.*:* **::*****:**.*:******* *: : ** .*:*.* ******** ****:.*.:: :* . : *** **.::* *****:.**:***. .*:* ..:*::*****:**.*::* ***::*..* :* .*** * : **:** *.: **. . *:*:*** *:*: **: * * ** : * : :..*. : .** * : ******:* .: ", "identical_positions": 498, "similar_positions": 355, "identity": "36.83%" }, { "cls_id": "homologset.agr.RGD:620957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJ46-1", "uniprot_id": "EBP_RAT", "id": "Q9JJ46-1", "name": "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "aln": "MTTNMLPLHPYWPRHLRLDNFVPNDLPTWHILVGLFSFSGVLIVITWLLSSRVSVVPLGTGRRLALCWFAVCTFIHLVIEGWFSFYHEILLEDQAFLSQLWKEYSKGDSRYILSDGFIVCMESVTACLWGPLSLWVVIAFLRHQPFRFVLQLVVSVGQIYGDVLYFLTELRDGFQHGELGHPLYFWFYFVIMNAIWLVIPGILVFDAIKHLTNAQSMLDNKVMKIKSKHN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70245-1", "uniprot_id": "EBP_MOUSE", "id": "P70245-1", "name": "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "aln": "MTTNTVPLHPYWPRHLKLDNFVPNDLPTSHILVGLFSISGGLIVITWLLSSRASVVPLGAGRRLALCWFAVCTFIHLVIEGWFSLYNGILLEDQAFLSQLWKEYSKGDSRYILSDSFVVCMETVTACLWGPLSLWVVIAFLRQQPFRFVLQLVVSMGQIYGDVLYFLTELHEGLQHGEIGHPVYFWFYFVFLNAVWLVIPSILVLDAIKHLTSAQSVLDSKVMKIKSKHN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15125-1", "uniprot_id": "EBP_HUMAN", "id": "Q15125-1", "name": "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "aln": "MTTNAGPLHPYWPQHLRLDNFVPNDRPTWHILAGLFSVTGVLVVTTWLLSGRAAVVPLGTWRRLSLCWFAVCGFIHLVIEGWFVLYYEDLLGDQAFLSQLWKEYAKGDSRYILGDNFTVCMETITACLWGPLSLWVVIAFLRQHPLRFILQLVVSVGQIYGDVLYFLTEHRDGFQHGELGHPLYFWFYFVFMNALWLVLPGVLVLDAVKHLTHAQSTLDAKATKAKSKKN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** *******:**:******** ** ***.****.:* *:* *****.*.:*****: ***:******* ********** :* ** ************:********.*.* ****::******************::*:**:******:************* ::*:****:***:*******::**:***:*.:**:**:**** *** ** *. * ***:*", "identical_positions": 173, "similar_positions": 37, "identity": "75.22%" }, { "cls_id": "homologset.agr.RGD:620958", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W4R3-1", "uniprot_id": "Q9W4R3_DROME", "id": "Q9W4R3-1", "name": "", "aln": "---------------------------------------MPVSAKRLLRNFQFTS------------------------CDRNGKMLIHLLLIVS-----------------------------------------------------------LLEAIGAFQPEFVESISNVSVAVGRDATFTCHVRHLGGYRVG-----------WLKADTKAIQAIHENVITHNPR---VTVSHLDQN---TWNLHIKAVSEEDRGGYMCQLNTD-PMKSQIGF-LDVVIPPDFIS--EDTSSDVIVPEGSSVRLTCRARGYPEPIVTWRREDGNEIVLKD-NVGTKTLAPSFRGEVLKLSKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHPVIQVPNQLVGAPLGTDVQIECHVEASPKSINYWIK----------------DTG----EMIVTSGKYHVQESS-QSMYETKMSMIVRKFQKDDVGSYRCIAKNSLGEVDSSIRLYEIP-GPNRNKNPLNGGGKGGGAGGSLDADANDILKQKQQVKVTYQPEDEELQYGSVEDFEAEGGEGGGLTPLSPHVYYTSGNKPATHKPGNSGGNQHLHQQHHHHHHHNNNNNNQQHSGGPGGGPTGGD-----------AGSLGGEMGGITRKPPPYYGGNTEVRGPIDNNEMSSGSGDSRLCRGHHLPILLLPFARLILVRSWHCRHTFL---------------------------------MGLSQACLPGLLLSLL-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z153-1", "uniprot_id": "B7Z153_DROME", "id": "B7Z153-1", "name": "", "aln": "--------MMNLLVVKESGERIADISCSQEHTTKFSPKLSQVAKHRKLAQLEIASGSGLVGLG--------TGTGTGSGCGPAIRWQLLLLLLLGNCIDLT--------------------------------------------------VSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVITNNDR---LSVQHNDYN---TWTLNIRGVKMEDAGKYMCQVNTD-PMKMQTAT-LEVVIPPDIIN--EETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARN-GSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQR----------------ENG----EMIIAGDRYALTEKE-NNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRLYEME-RPG--KKILR------------DDDLNEVSK-NEVVQKDTRSED-------------------GSRNLNGRLYKDR----APDQHPASGSDQLLGRGTMRLIGTFLLALLVLFTALAEAGPTTLS-----------CRTKGGRQ---KKAKETSWNGRRARDGREDGH-----AAEWRQCWER---------------SALSWRRSAP---------------------------------PELDYYSLIQL----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAR6-1", "uniprot_id": "Q9VAR6_DROME", "id": "Q9VAR6-1", "name": "", "aln": "--------------------------------------MEKLLQSTLFVILIMAT-----------------------KCGSGSTQNQHHE----------------------------------------------------------------SSSQLDPDPEFIGFINNVTYPAGREAILACSVRNLGKNKVG-----------WLRASDQTVLALQGRVVTHNAR---ISVMHQDMH---TWKLKISKLRESDRGCYMCQINTS-PMKKQVGC-IDVQVPPDIIN--EESSADLAVQEGEDATLTCKATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDVPPAVSKRVSLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASPSPVSYWLKGARTSNGFASVSTASLESGSPGPEMLLDGPKYGITER--RDGYRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEIKLHPG--ASASN------------DDHLNYIGGLEEAAR-------------------------------------------------NAGRSNRTTWQPLLAMLMLLWMRLSLRTGGA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7PLL7-1", "uniprot_id": "Q7PLL7_DROME", "id": "Q7PLL7-1", "name": "", "aln": "----------------------------------------MLTKKTARIKMYNGT------------------------LACSIAFILIKAITITKCHAVA--------------------------------------------------HIHGKGESEEIDPQFLAKLSNTTVPIGRDISFTCVVDNLGHYRVA-----------WIKSDSKAILGIHTHMVSLNPR---LSVTHNGHN---TWKLHISRVQINDSGSYMCQVNTD-PMKSLSGY-LDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRPKVLWRREAGKEIILRT-DGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPPSVSKRFNVYVNFSPTVKAISQLVGAPVEREVTLECIVEVFPKPLNGWYR----------------SEGN---IKLHNGNKYNISEEV-INIYTWHLNLTIRHLTKSDFGTYSCSSVNALGKSESLIRLQELRLPPKLTTTPTPHMQTTGKS--RRKHPASHKKGLNEVLRFQETHFAN-------------------QIQQENEDHNEGFDLLKFTNSENSNIVLESGHINSMINKEDVNIYHPKQYGQEKTNKPSGT-----------IPSTRTPWILTNAGSQRPALTSYATVALITSFWLFFWRVFHSLDWDAIRVSSVVHHVVVFKRRSYFEAPNYA---------------------------------LRITVLQMLQELRTLVIEQ--------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMN9-1", "uniprot_id": "Q9VMN9_DROME", "id": "Q9VMN9-1", "name": "", "aln": "-------------------------------------------MQSNFCQCRKQ--------------------------TCALSVILLLILMSQQCYPQR---------------------------------------------VEVPAEVIVD-------PKFSSPIVNMTAPVGRDAFLTCVVQDLGPYKVA-----------WLRVDTQTILTIQNHVITKNQR---IGIANSEHK---TWTMRIKDIKESDKGWYMCQINTD-PMKSQMGY-LDVVVPPDILDY--PTSTDMVVREGSNVTLKCAATGSPEPTITWRRESGVPIELAT-----GEEVMSIEGTDLVIPNVRRHHMGAYLCIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINYWTRER---------------GEIVP-----PGGKYSANVTE-IGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKLYRIPPN--------------------AVNYVENFEARHKGKKRTK------------SSES-------HHPARAQEHSGEDMENP-----GKRKADLS--------LGAES--------IDSIYGNSA--------------AGSRRR--------------------------QDLGGVLLLLLPVAVAVAMSLATAGVMRETQMTLPPQT------------------------------------LTHV---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMN6-1", "uniprot_id": "Q9VMN6_DROME", "id": "Q9VMN6-1", "name": "", "aln": "----------------------------------MKIKIFPLTADAATIAARRQRRRAAGKLQRKREMPEISSRLIVATATAAVVSIICLSLALPGCAAQESDDEGELHHLDQMHHQHQDFIIGESEEHDHIAHHLAEMQNKDELLEDIREDTVVNAIPEKDLPKFGELLQNVTVPVSREAVLQCVVDNLQTYKIA-----------WLRVDTQTILTIQNHVITKNHR---MSITHAEKR---AWILRIRDVKESDKGWYMCQINTD-PMKSQVGY-LDVVVPPDILDY--PTSTDMVIREGSNVTLKCAATGSPTPTITWRREGGELIPLPN-----GAEAVAYNGSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVMLIVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINYWMKN----------------DTIIV-----PGERFVPETFE-SG-YKITMRLTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLYHIPQTTTMTTMAPT----------VSINTVPVVLVKYNKEQRYG------------SSQNSNTNPYNFNPGNSQQNTKLQRGKS-----NSKGSDQSPSGLNNVFVGATSSLWNSQDHHSSSSSSSS--------------ASSRGRDH---HQQQHHQQQQQNHGSDHGASYRSDGKSPHLTNHDAKSLTDDLDRMQDLKGWASRLSPISP--------------------------------ILGLSMILGVGYLGPWPG----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IP70-1", "uniprot_id": "Q8IP70_DROME", "id": "Q8IP70-1", "name": "", "aln": "---------------------------------MAMAGPHRLPRPHTRRRFRLQAEFN------------VRQLAITIIATAAVTMLMTATPTLAEIPSKG---------------------------------------------KHTRLDTQQTAQEDSDFPRFAEPIANVTVSVGRDALMACVVENLKGYKVA-----------WVRVDTQTILSIHHNVISQNSR---ISLTYNDHR---SWYLHIKEVEETDRGWYMCQVNTD-PMRSRKGY-LQVVVPPIIVEG--LTSNDMVVREGQNISLVCKARGYPEPYVMWRREDGEEMLIG------GEHVNVVDGELLHITKVSRLHMAAYLCVASNGVPPSISKRVHLRVQFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYWTTER---------------GDMIISDTSRAGDKYETTSTV-SG-YTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTP-------TT----------AIISEMSLLNRSYDGKRRHRNKFDSANALPDYGVEEWRDGAQGNNAGNNGDNNQTPVRNPPGAFHNSAGSLAQHNLLAKIMLGIKTQSFGIFKRLSSSLPLAAGQSFLWLSTLSLVSAPSRWRMSNVENRPNSPETVVNNDTAAECWETRSHCVSESNNNNNSRITQRPPMWARHLRIFHIAHTPCGASTQYQRLCERQWQWQRLWQWQCQWKWQHQWQWPMLICIVILAGCFVRWLPMLLHFIGRHIGTFSISATHRQHLMCTFWDNRGNKVVAKNTTPARPSTFEMLCSRMFSR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLF0-1", "uniprot_id": "Q9VLF0_DROME", "id": "Q9VLF0-1", "name": "", "aln": "MLPPSWHLIGALLVLAATAGDSTNKIILPQILNGGGGGGGVGTAQGKHPSGSKTVATGVVPNFGGAAGNGAGGGGPVAGSGTGSTVVGSNGVIVAGGGANVP---------------------------------------------------TSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSYKVA-----------WMHFEQSAILTVHNHVITRNPR---ISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTV-TAKTQFGY-LNVVVPPNIDDS--LSSSDVIVREGANISLRCRASGSPRPIIKWKRDDNSRIAINK-----NHIVNEWEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGE--------------------GPIIHDSHKYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPPTTASSGIYS------------TDTHWGENGINNNYAYGG-------------------------PDSTRSIYAQDKNTRYQSNLNEIGLSEQKSFLDKTQNPLLANGNANEADAESNGARGHNP--------------------------------------------------SMAIAWLFVVIATLLLTIRSAVGSSHSLSLC--------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q62718-1", "uniprot_id": "NTRI_RAT", "id": "Q62718-1", "name": "Neurotrimin", "aln": "----------------------------------------MGVCGYLFLP-----------------------------WKCLVVVSLRLLFLVPTGVPVR-----------------------------------------------------------SGDATFPKAMDNVTVRQGESATLRCTIDNR-VTRVA-------------WLNRSTILYAGNDKWCLDPR---VVLLSNTQT---QYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVH-LIVQVSPKIVEI----SSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVS------------EDEYLEIQGITREQSGEYECSASNDVAAPVVRRVNVTVNYPPYISEAKG-TGVPVGQKGTLQCEASAVPSAEFQWFKDD---------------------KRLVEGKKGVKVENR-----PFLSRLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFGPG----------------------------AVSEVNNGTSR------------------------------------------------RAGCIWLLPLLVLHLLLKF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PJ0-1", "uniprot_id": "NTRI_MOUSE", "id": "Q99PJ0-1", "name": "Neurotrimin", "aln": "----------------------------------------MGVCGYLFLP-----------------------------WKCLVVVSLRLLFLVPTGVPVR-----------------------------------------------------------SGDATFPKAMDNVTVRQGESATLRCTIDNR-VTRVA-------------WLNRSTILYAGNDKWCLDPR---VVLLSNTQT---QYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVH-LIVQVSPKIVEI----SSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVS------------EDEYLEIQGITREQSGEYECSASNDVAAPVVRRVKVTVNYPPYISEAKG-TGVPVGQKGTLQCEASAVPSAEFQWFKDD---------------------KRLVEGKKGVKVENR-----PFLSKLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFGPG----------------------------AVSEVNNGTSR------------------------------------------------RAGCIWLLPLLVLHLLLKF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P121-1", "uniprot_id": "NTRI_HUMAN", "id": "Q9P121-1", "name": "Neurotrimin", "aln": "----------------------------------------MGVCGYLFLP-----------------------------WKCLVVVSLRLLFLVPTGVPVR-----------------------------------------------------------SGDATFPKAMDNVTVRQGESATLRCTIDNR-VTRVA-------------WLNRSTILYAGNDKWCLDPR---VVLLSNTQT---QYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVH-LIVQVSPKIVEI----SSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVS------------EDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKG-TGVPVGQKGTLQCEASAVPSAEFQWYKDD---------------------KRLIEGKKGVKVENR-----PFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFGPG----------------------------AVSEVSNGTSR------------------------------------------------RAGCVWLLPLLVLHLLLKF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15364-1", "uniprot_id": "AMAL_DROME", "id": "P15364-1", "name": "Protein amalgam", "aln": "--------------------------------------------------------------------------------MARLRLLIGLIFCLAISLDSVLS-----------------------------------------------------------APVISQISKDVVASVGDSVEFNCTVEEVGQLSVSWAKR-------PSESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPVIAEN---TPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGG---------HLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHKNG----------------------VPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHADARLHLFQTVIP---------------------------VPSLS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . : * : . :. . .:: : : : : :.* : * * * *.: . : : : .* : . . . ** . * * . * * * : * : : * : : * . . * * *.*. . : . : :.: * : . : * . * . * . : : . . : * * * : * * :. : * ", "identical_positions": 31, "similar_positions": 65, "identity": "3.77%" }, { "cls_id": "homologset.agr.RGD:620959", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MIY3-1", "uniprot_id": "A0A096MIY3_RAT", "id": "A0A096MIY3-1", "name": "G/T mismatch-specific thymine DNA glycosylase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAEAARSYSLEQVQALYSFPFQQMMAEAP---------------------NMADVAGQQMPAEAP---------------AQDPVPEAPKRRKRKTRAAEAQDPVEPKKPAASKKSGKSTKSKEKQEKITDTFKVKRKVDRFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIERSTDVQEVQYT---FDLQLAQEDAKRTAVKEEKYDPGYEAAYGGACGENPCNGEPCGFASNGLTANSAELGGESAPSDVPNGQWMAQSFAEQIPSFNN-CGTGEQEAGSHAGSHA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56581-1", "uniprot_id": "TDG_MOUSE", "id": "P56581-1", "name": "G/T mismatch-specific thymine DNA glycosylase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAEAARSYSLEQVQALYSFPFQQMMAEVP---------------------NMAVTTGQQVPAVAPNMATVTEQQVPEDAPVQEPAPEAPKRRKRKPRAAEPQEPVEPKKPATSKKSGKSTKSKEKQEKITDAFKVKRKVDRFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIERNADVQEVQYT---FDLQLAQEDAKKMAVKEEKYDPGYEAAYGGAYGENPCNGEPCGIASNGLTAHSAEPRGEAAPSDVPNGQWMAQSFAEQIPSFNN-CGTREQEEESHA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13569-1", "uniprot_id": "TDG_HUMAN", "id": "Q13569-1", "name": "G/T mismatch-specific thymine DNA glycosylase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAENAGSYSLQQAQAFYTFPFQQLMAEAP---------------------NMAVVNEQQMPEEVP-----------APAPAQEPVQEAPKGRKRKPRTTEPKQPVEPKKPVESKKSGKSAKSKEKQEKITDTFKVKRKVDRFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLKGIERNMDVQEVQYT---FDLQLAQEDAKKMAVKEEKYDPGYEAAYGGAYGENPCSSEPCGFSSNGLIES-VELRGESAFSGIPNGQWMTQSFTDQIPSFSNHCGTQEQEEESHA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V4D8-1", "uniprot_id": "Q9V4D8_DROME", "id": "Q9V4D8-1", "name": "G/T mismatch-specific thymine DNA glycosylase", "aln": "MQEESGSTPLLSSSFSYTPTVAPLVLKIALIQAARSFAASKYTIKVLLSLNLALSEQAIVQKAVKPICTVMASEVDASSGPEDGTVPTLMSLTPYITNLEHGNNESGKYVSGLPNNRKRQKLSILEHNTIQNNDVDNTEVEPNMDPKSKMSDTKSNKYSEMEKHLNDNSKIVIEGTISIGNSKRKSPEKLVPYDNDCYMPPEQALVTSVELVVPAPQTHSSNTPGRQSEEPNLSTLGESSTTPSSTIDNKLQYSTAGLYNSTSSTSILANDKIVGCANDSSNLNLRIPTKLVVTTASGDILIDDRRASLWTPHHDESGQRQQRTGTASSDTKQEPMNVSSELSYHHQNRHSELLLQIEKESSGSFLQASPIPLQDNHNNAASGQFGQTEETSNIDSQSHNNFYAQMMQPQHLLHNQHQQSMHEHSPRHQQPASYSGYITHYQNPPMFGAHQSEHHQRLNQQQQPLQHLLDCHGHLEQSTPISQQNQHHLSQQIHQHQHQQTHQRLPLRENYHDIIMDDFHEEPSHAFKLTLSPSNTKPENQDDGYETSAGDVLTPNSHSSSTHSITPQHQMQHSNIVLMTQNQKKSDDLQLTKVTLSGEAHTDPNACSSNSSQGQVLASQSHLELSEGTRCSSHASVVDPYSFMGEELHMHSPSHRHLDAVTTGPGRYGILVSNDTPECLSREMYRHSQQSTTVLEQTDSSSCGINFKPMPKKRGRKKKLVAVNADTSQMTTPVDQQKVSAGRADCEDGGGDQAAKPKERKKHDRFNGMSEEEVIKRTIPDHLCDNLDIVIVGINPGLFAAYKGHHYAGPGNHFWKCLYLAGLTQEQMSADEDHKLI-KQGIGFTNMVARATKGSADLTRKEIKEGSRILLEKLQRFRPKVAVFNGKLIFEVFS------GKKEFHFGRQPDRVDGTDTFIWVMPSSSARCAQLPRAADKVPFYAALKKFRDFLNGQIPHIDESECVFTDQRIRLCSAQQQVDIVGKINKTHQPPLGDHPSSLTVVSNCSGPIAGDAECGIVAEESDQVQSEKMIPQMDPTVPSSSNATDGKSFSYTAENTPLLPVSNHNPSINENNYLSVMGSQQPLSQQPLEKKKRGRPKKIKGQDIIDHSVGGKASIAGQHIPSHDFNNILNLSVMSGGGTIETPKKKRGRPKKLKPAIDNIMTVKQLQHGNNNLNTTAGLSASSMHPISMEHIAASPQSSHQMPPSLYNTPPPSHLLYTASASPMASPALNCNYTQVHGHGTPPVGQVASVAQGSSPVIDTQNDHLAQQKQSHHGNLGAGLDMRDHPHLGETPPPSSPNMCSTVDFDPPDEHSGSQVGSRVQNKAVELDHQHPQIMEKVQYDSPVPNTEANPAHPHENYQQWLSPHPHQSNQPAQKLTHRQQHPPMHHFHQEQTENWQRYEEQNSNPYMVISAHHQHLSPRLGNQTHQNSSPSGHISSDVAHKSLCGLESLVDQIPAIREQDCSNIPLATVAAAAAAVESRILSLQHQHQHPLQPHQQNQQNQQQQLKQCKQENSAHRESCRPTSENSNVSNSNFSVSSLAASASSARTDNAIYGNGETKGNNESSHHNSCDTNIDYPIHNQSAYHHTPHLIGSALGTNVNNSEPNLHTISHPHPPHPHPHSMYVDQAHHMAHIPSVNVNSMYGPAYGSHPQHTTGEYPGTHGHYSLGGSVQTAVPTSSATLHVPSPNYPFGHHPYGHTPPQANYPSYTHPHTHHHHSHPSHHLTVFDHLKPSDISGYGGF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : . * .. *:* ::: . * : . ::: : : **:* :.:.. . .. .* *. :..:: . : * ::* *****:** *::.:*:** * ******:******:********.**********:::**:: *:. :**.* * ******** *:* ** **: **::**.***::***:::*::****** *:*:** *::.** **.:: .*:*: :***********:*** *** :* **.:** *:* * .* :* : * **::.. . ::.::* .. . *.. .* :. *: : . : :.* : : **. . . *: ", "identical_positions": 141, "similar_positions": 117, "identity": "8.08%" }, { "cls_id": "homologset.agr.RGD:620961", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62074-1", "uniprot_id": "KPCI_MOUSE", "id": "Q62074-1", "name": "Protein kinase C iota type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MPTQ--RDSSTMSHTVACGGGGDHSHQVRVK-----------------------------AYYRGDIMITHFEPSISFEGLCSEVRDMCSFDNEQPFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPE----------------------------------------------------------------RPGMPCPGEDKSIYRRGAR----------------------------------------RWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRH--------------------------------------------------------------------------------------------------------------------------------------SLPPEPMMPMDQT-MHPDHTQTVIPYNPSSHESLDQVGEEKEAMN---------------------------------------------------------------------------------------------------------------------------------------------------------------TRESGKASSSLG------LQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASN--HPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M7Y5-1", "uniprot_id": "KPCI_RAT", "id": "F1M7Y5-1", "name": "Protein kinase C iota type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MPTQ--RDSSTMSHTVACGGGGDHSHQVRVK-----------------------------AYYRGDIMITHFEPSISFEGLCSEVRDMCSFDNEQPFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPE----------------------------------------------------------------RPGMPCPGEDKSIYRRGAR----------------------------------------RWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRH--------------------------------------------------------------------------------------------------------------------------------------SLPPEPMMPMDQSSMHPDHTQTVIPYNPSSHESLDQVGEEKEAMN---------------------------------------------------------------------------------------------------------------------------------------------------------------TRESGKASSSLG------LQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASN--HPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41743-1", "uniprot_id": "KPCI_HUMAN", "id": "P41743-1", "name": "Protein kinase C iota type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MPTQ--RDSSTMSHTVAGGGSGDHSHQVRVK-----------------------------AYYRGDIMITHFEPSISFEGLCNEVRDMCSFDNEQLFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPE----------------------------------------------------------------RPGMPCPGEDKSIYRRGAR----------------------------------------RWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRH--------------------------------------------------------------------------------------------------------------------------------------SLPQEPVMPMDQSSMHSDHAQTVIPYNPSSHESLDQVGEEKEAMN---------------------------------------------------------------------------------------------------------------------------------------------------------------TRESGKASSSLG------LQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASN--HPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90XF2-1", "uniprot_id": "KPCI_DANRE", "id": "Q90XF2-1", "name": "Protein kinase C iota type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MPTL--RDS-TMSHP------GENPHQVRVK-----------------------------AYYRGDIMITHFEPSISYEGLCNEVRDMCSMDNDQLFTMKWIDEEGDPCTVSSQLELEEALRLYELNKDSELIIHVFPCVPE----------------------------------------------------------------KPGMPCPGEDKSIYRRGAR----------------------------------------RWRKLYYATGHAFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTVECGRQ--------------------------------------------------------------------------------------------------------------------------------------VIQDPMIGRIDPGSTHPEHPDQVLGKK-NSTESINHEGEEHEAVG---------------------------------------------------------------------------------------------------------------------------------------------------------------SRESGKAVSSLG------LIDFDLLRVIGRGSYAKVLLVRLKKTERIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASN--HPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKGFLNKESKERLGCHPQTGFADIMAHPFFRNVDWDLMEQKQVVPPFKPNISGEFGLDNFDAQFTNEPIQLTPDDDDAVKKIDQSEFEGFEYINPLLMSAEECV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9X0-1", "uniprot_id": "APKC_DROME", "id": "A1Z9X0-1", "name": "Atypical protein kinase C", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MQKMPSQILNDGSSVSLNSASMNMANTPNSITVK-----------------------------TAYNGQIIITTINKNISYEELCYEIRNICRFPLDQPFTIKWVDEENDPCTISTKMELDEAIRLYEMNFDSQLVIHVFPNVPQ----------------------------------------------------------------APGLSCDGEDRSIYRRGAR----------------------------------------RWRKLYRVNGHIFQAKRFNRRAFCAYCQDRIWGLGRQGFKCIQCKLLVHKKCHKLVQKHCTDQ--------------------------------------------------------------------------------------------------------------------------------------PEP-LVKERAEESSDPIPVPLPPLPYEAMSGGAEACETHDHAHIV---------------------------------------------------------------------------------------------------------------------------------------------------------------APPPPEDPLEPGTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASN--HPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLDSDRDLANFPPEFTGEAVQLTPDDDHVIDNIDQSEFEGFEYVNPLLMSLEDCV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24583-1", "uniprot_id": "KPC1_YEAST", "id": "P24583-1", "name": "Protein kinase C-like 1", "aln": "MSFSQLEQNIKKKIAVEENIIRGASALKKKTSNVMVIQKCNTNIREARQNLEYLEDSLKKLRLKTAQQSQGENGSEDNERCNSKEYGFLSTKSPNEHIFSRLDLVKYDCPSLAQRIQYMLQQLEFKLQVEKQYQEANTKLTKLYQIDGDQRSSSAAEGGAMESKYRIQMLNKALKKYQAINVDFDQFKHQPNDIMDNQQPKFRRKQLTGVLTIGITAARDVDHIQSPMFARKPESYVTIKIDDTIKARTKPSRNDRWSEDFQIPVEKGNEIEITVYDKVNDSLIPVAIMWLLLSDIAEEIRKKKAGQTNEQQGWVNASNINGGSSLASEEGSTLTSTYSNSAIQSTSAKNVQGENTSTSQISTNSWFVLEPSGQILLTLGFHKSSQIERKQLMGGLHRHGAIINRKEEIFEQHGHHFVQKSFYNIMCCAYCGDFLR---YTGFQCQDCKFLCHKKCYTNVVTKCIAKTSTDTDPDEAKLNHRIPHRFLPTSNRGTKWCCHCGYILPWGRHKVRKCSECGIMCHAQCAHLVPDFCGMSMEMANKILKTIQDTKRNQEKKKRTVPSAQLGSSIGTANGSDLSPSKLAERANAPLPPQPRKHDKTPSPQKVGRDSPTKQHDPIIDKRISLQTHGREKLNKFIDENEAYLNFTEGAQQTAEFSSPEKTLDPTSNRRSLGLTDLSIEHSQTWESKDDLMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHIDLETKQKLDWENKNDFREADLTIDSTHTNPFRDMNSETFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQR-LSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGD---------DEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRD-ADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTLTPLP-SVLTTSQQEEFRGFSFMPDDLDL-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. *. * : : : . :. . : : .*: .::. : :. :*: .. * .:: : . :: ..:: * *: * : .. **: * : .:. * .::: ** * * * . ** * * : *::* :**:* ****:. * .* : . : : . .:: : . : . * :* *::*:*:*.:.**:: . :.* *: *:**:** : ::.**: .::**:** *:: ****..*:..*** .*::*.:*:: *****:*:*.** *. .:*:**:**: ***:::*:.*:*******:*:** *****::***:**: : *: ********:::*****: ::* :*****:***:::*: :***. ** :*:.** . * .:: . ..:::.:*.*:. .***. . :: .***:*:::: : . :* **: *.:.. . * :**. . *** : . :*.**.**.:: * ", "identical_positions": 163, "similar_positions": 196, "identity": "13.92%" }, { "cls_id": "homologset.agr.RGD:620962", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1A6-1", "uniprot_id": "VIGLN_RAT", "id": "Q9Z1A6-1", "name": "Vigilin", "aln": "-MSSVAVLTQESFAEHRSGLVPQQIIVATLNS----EEESDPPTYKDAFPPLPEKAACLESAQEPAGA-----WSNKIRPIKASVITQVFHVP---------------LEERKYKDMN---QFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRP----------DDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVKRLEVEK-AFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVSAPSWLHRFIIGKK---------------GQNLAKITHQMPKVHIEFTEGEDKITLEG---PTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHR------HLIGKSGANINRIKDQYKVS---VRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFP--EVIINFPDPAQKSEIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE------TIVITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARIIF------PAAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDYMLVDPRHHRHFVIRRGQVLREIAEEYGG-----VMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQITRDYNVQIKFPDREENPVHSVEPSIQENGDEAGEGREAKETDPGSPRRCDIIVISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYIIGQKGSGIRKMMDEFEVNIHVPAPELQSHTIAITGLAANLDRAKAGLLDRVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGGKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILKIVGELEQMVSEDVP-----LDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPP-----AHEESKAPSKGFVVRDAPWTSNSSEKAPDMSSSEEIPTFGAQVAP--KTLPWGPKR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDJ3-1", "uniprot_id": "VIGLN_MOUSE", "id": "Q8VDJ3-1", "name": "Vigilin", "aln": "-MSSVAVLTQESFAEHRSGLVPQQIKVATLNS----EEENDPPTYKDAFPPLPEKAACLESAQEPAGA-----WSNKIRPIKASVITQVFHVP---------------LEERKYKDMN---QFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRP----------DDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEK-AFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVSAPSWLHRFIIGKK---------------GQNLAKITQQMPKVHIEFTEGEDKITLEG---PTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHR------HLIGKSGANINRIKDQYKVS---VRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFP--EVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE------TIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARIIF------PAAEDKDQDLITIIGKEDAVREAQKELEALIQNLENVVEDYMLVDPKHHRHFVIRRGQVLREIAEEYGG-----VMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTVECAIPQKFHRSVMGPKGSRIQQITRDYNVQIKFPDREENPVHSVEPSIQENGDEAGEGREAKETDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYIIGQKGSGIRKMMDEFEVNIHVPAPELQSDTIAITGLAANLDRAKAGLLDRVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHEVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILKIVGELEQMVSEDVP-----LDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPP-----AHEESRAPSKGFVVRDAPWTSNSSEKAPDMSSSEEFPSFGAQVAP--KTLPWGPKR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00341-1", "uniprot_id": "VIGLN_HUMAN", "id": "Q00341-1", "name": "Vigilin", "aln": "-MSSVAVLTQESFAEHRSGLVPQQIKVATLNS----EEESDPPTYKDAFPPLPEKAACLESAQEPAGA-----WGNKIRPIKASVITQVFHVP---------------LEERKYKDMN---QFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRP----------DDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEK-AFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAAPSWLHRFIIGKK---------------GQNLAKITQQMPKVHIEFTEGEDKITLEG---PTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHR------HLIGKSGANINRIKDQYKVS---VRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFP--EVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSE------TIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIF------PAAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGG-----VMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVP-----LDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPP-----AHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEFPSFGAQVAP--KTLPWGPKR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDG6-1", "uniprot_id": "A0A8M2BDG6_DANRE", "id": "A0A8M2BDG6-1", "name": "Vigilin", "aln": "-MSSVAVLTQESFNEHRSGLLPEQVKAAAGGDPSSVEDDDSLPTYKDAFPPLPEKP-LPEGVQETENA-----WTTKIKPLKSSIITQVFHVP---------------LEERKYKDMN---QFGEGDQAKVCLDIMHKTGAHLELSMAKDQGLSIMVSGKYDAVMKARKEIVSRLQTQASATVAIPKEHHRFVIGKSGEKLQELELKTATKIQIPRP----------DDPSNQIKISGTKEGLEKAKHEILLISAEQDKRAVERMNIDK-VFHPFITGAHGKLVGDLMQETGARINVPPPSVNKTEIVITGEKEQVALAMVKIKKLYEEKKKNATTIAVEVKKSQHKYVIGPKGNTLQEILERTGVSVEIPPLDSSSETVILRGEPARLGQALTEVYAKANSYTVSSVSAPSWLHRFIIGKK---------------GQNLAKITQQMPKVHIEFTEGEDKITLEG---PTKDVQIVQGQIEVIVTDLVSRMDYTEISVDPKFHR------HLIGKGGANINRIKELHKVS---VRIPPDNEKSNLIRIEGDPQGVQEAKKELLELASRMENERTKDMIIEQRFHRAIIGQKGEKIKEIRDKFP--EVIINFPDPAQKSDIVQLRGPRTEVEKCSKFMQKMVAEMVENSFSVSVPIFKQFHKNIIGKGGANIKKIREETNTKIDLPAENSNSE------MIVITGKKANCEAAKNRILAIQKELANITEVEVSIPSKLHNSLIGSKGRFVRSIMEECGGVHIHFPTEGSGIDAVTIRGPAEEVEKAKKQLLSLAEEKQTKSHTVELRAKPEYHKFLIGKGGGNIRKVRDSTGARIIF------PTAEDKDHELITVIGTEEAVAEAQKELEALIKSLDNIVEDFMIVDPKHHRFFVARRGQVLRDIADEYGG-----VIVSFPRTAAQSDKVTLKGAKDCVEAAKKRMLEMIEDLDAQVTMECVIPQKFHRSIMGPKGSRIQQITKDHNVQIKFPDREEQ--QQADASVQENGEANGEVKEP--VDPTAPKKCDVIVLSGRKERCEAAVEALKALVPVTIAVEVPFELHRYIIGQKGSGIRKMMDEFEVNIQVPAHELQSDIISITGLASHLDRAKEGLLERVKELQAEQEDRALRSFKLTITVEPKYHPKIIGRKGAIISHIRHDHEVNIQFPEKNDENQ--DQITITGYEQNAIAARDAIQAIVDELEEMISEDIT-----LDSRVHARIIGARGKGIRKIMDEFKVDVRFPQSGAADPNLVTVTGRPEHVDEAIDHLLNLEEEYMADVVENEAKMAYMKPSGSSASSMEEPRGPSKGFVVREAPWATGN-EKAPDMSSSEEFPSFGAPVAAAARASPWGPKRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P06105-1", "uniprot_id": "SC160_YEAST", "id": "P06105-1", "name": "Protein SCP160", "aln": "MSEEQTAIDSPPSTVEGSVETVTTIDSPSTTASTIAATAEEHPQLEKKPTPLPSLKDLPSLGSNAAFANVKVSWGPNMKPAVSNSPSPSPSAPSLTTGLGAKRMRSKNIQEAFTLDLQSQLSITKPELSRIVQSVKKNHDVSVESTLSKN-ARTFLVSGVAANVHEAKRELVKKLTKPINAVIEVPSKCKASIIGSGGRTIREISDAYEVKINVSKEVNENSYDEDMDDTTSNVSLFGDFESVNLAKAKILAIVKEETKNATIKLVVEDEKYLPYID------VSEFASDEGDEEVKVQFYKKSGDIVILGPREKAKATKTSIQDYLKKLASNLDEEKVKIP-SKFQFLID-----AEELKEKYNVIVTFPSTPD-DELVSFVGLRDKVGEAITYARSSSKSYVVESLDISKAHSKNLTHAKNLIMYFTKYSVLKGLEESHPNVKISLPSIQSLPTAETVTIHISAKSDEANDIKAVRKELISFVNNIPPSETLVITDLDYELFGGSIKHCLLASESSVAFVQFGDYYPNDNSILLVALTEDEDFKPSIEEIQASLNKANESLNSLRTKQNNMETKTYEFSEEVQDSLFKPSSATWKLIMEDISEQEGHLQIKLHTPEENQLTVRGDEKAAKAANKIFESILNSPSSKSK-MTVNIPANSVARLIGNKGSNLQQIREKFACQIDIPNEENNNASKDKTVEVTLTGLEYNLTHAKKYLAAEAKKWADIITKELIVPVKFHGSLIGPHGTYRNRLQEKYN-VFINFPRDN---EIVTIRGPSRGVNKAHEELKALLDFEMENGHKMVINVPAEHVPRIIGKNGDNINDIRAEYGVEMDFLQKSTDPKAQETGEVELEITGSRQNIKDAAKRVESIVAEASDFVTEVLKIDHKYHKSIVGSGGHILREIISKAGGEEIRNKSVDIPNADSENKDITVQGPQKFVKKVVEEINKIVKDAENSVTKTIDIPAERKGALIGPGGIVRRQLESEFNINLFVPNKDDPSGKITITGAPEN------------VEKAEKKILNEIIREN-----------------FDREVDVPASIYEYVS-ERGAFIQKLRMDLSVNVRFGNTSKKANKLARAPIEIPLEKVCG---------STEGENAEKTKFTIEEVGAPTSS-----EEGDITMRLTYEP-IDLSSILSDGEEKEVTKDTSNDSAKKEEALDTAVKLIKERIAKAPSATYAGYVWGADTRRFNMIVGPGGSNIKKIREAADVIINVPRKSDKVNDVVYIRGTKAGVEKAGEMVLKSLRR--------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :.: . . . * : .: .. * :. .***. . .:. * * :::* :. : .* ::* *:: .: : : ::: .: :. .. :* :::*: . :::*** * :*::::* :* . .*.: :*.: : :**..*..::::. .**::.: **.:.::.: * *.:: *: ::* * *: *.*. :: ::. : *:* *.:: .: * . : :**: * :*: : . *:. :: .: *:: *:.:::*. :*: *: .* * :*. . .* * : * ::*:*:* . :.::*:.*.*: .. : : * :. .::. .:*.:: * .* :.. ::*:: .: :: :*.:: . .:* ::. * .:... : :: : : . : :. .::. ** .:::*:..* .* :: :* .** :.:..: ::: .. : * :.:. * ::: : :.: : :** .. .: ..* ::.:: . .:* ::* * : .:**: *:*:::***: :**:* *:.*. : :** . * *:. : : *. *:* *: :* *:*.****.:* . : *: . *.*:** :. : *.****: *:**:::* * : : :...: :.. .*: :***.*.:*..:* . *..: * * *::... : : *..: : :* *.:*::: . .:.* : : :* ::*: :* *::**:* .: ** *.:*.: ::...:*::*.:. *: . :.: ::::* : .** ** : : :::** * :*: :..::: .*:::: : . . ** : : : *: .. . *:** .::.*: ::*: *:*: ::.**::. . ::. :: : : *::. .:* *: .*.: . *. :* : :: : :::. .:. :: : * .. :: * *: * .: : * . * * . *:*. *. *:** : .* :..*:.. : * : * *::* : :*: .. ", "identical_positions": 208, "similar_positions": 499, "identity": "15.23%" }, { "cls_id": "homologset.agr.RGD:620963", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P68101-1", "uniprot_id": "IF2A_RAT", "id": "P68101-1", "name": "Eukaryotic translation initiation factor 2 subunit 1", "aln": "MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLD-LNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEVDGDDDAEEMEAKAED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZWX6-1", "uniprot_id": "IF2A_MOUSE", "id": "Q6ZWX6-1", "name": "Eukaryotic translation initiation factor 2 subunit 1", "aln": "MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLD-LNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEVDGDDDAEEMEAKAED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05198-1", "uniprot_id": "IF2A_HUMAN", "id": "P05198-1", "name": "Eukaryotic translation initiation factor 2 subunit 1", "aln": "MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLD-LNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEVDGDDDAEEMEAKAED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P20459-1", "uniprot_id": "IF2A_YEAST", "id": "P20459-1", "name": "Eukaryotic translation initiation factor 2 subunit alpha", "aln": "MSTSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELSRRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQIP----LEELYKTIAWPLSRKFG----HAYEAFKLSIIDETVWEGIEPPSKDVLDELKNYISKRLTPQAVKIRADVEVSCFSYEGIDAIKDALKSAEDMSTEQMQVKVKLVAAPLYVLTTQALDKQKGIEQLESAIEKITEVITKYGGVCNITMPPKAVTATEDAELQALLESKELDN-RSDSEDDEDESDDE---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ****::*:**::*:*****:.********.****:*******************:****:*:*: .**:*****************.*: ****:*: *****:****: ** :: . **.*:: ** :. *: **:*** :: * :: :.:: .:* : * * *.:************:**:*:.******:*:**::. : *** * :*::*:*.* **:** :*:: :*:. *..*: *.* * : ** *: * **.** *:::** :* * :* . *.:** :* : : ", "identical_positions": 164, "similar_positions": 86, "identity": "51.9%" }, { "cls_id": "homologset.agr.RGD:620964", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WTQ1-1", "uniprot_id": "KPCD1_RAT", "id": "Q9WTQ1-1", "name": "Serine/threonine-protein kinase D1", "aln": "MSAPPLLRPPSPLLPAAAAVAAAAAALVPGSGP--APFPAPGAAPAGGISFHLQIGLSREPVLLLQDSSGDYSLAHVREMACSIVDQKFPECGFYGLYDKILLFRHDPASENILQLVKIASDIQEGDLIEVVLSAS----ATFEDFQIRPHALFVHSYRAPAFCDHCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVR-RRRLSNVSLTGLGTVRTASAEFSTSAPDEPLLSPVSPGFEQKSPSESFIGREKRSNSQSYVGRPIQLDKLLMSKVKVPHTFVIHSYTRPTVCQFCKKLLKGLFRQGLQCKDCRFNCHKRCAPKVPNNCLGEVTINGELLSPGA-ESDVVMEEGSDDNDSERNS------GLMD---DMDEAMVQDTEMALAEGQSDGAEMQD------------------PDADQEDSNRTISPSTSNNIPLMRVVQSVKHTKRRSSTVMKEGWMVHYTSKDTLRKRHYWRLDSKSITLFQNDTGSRYYKEIPLSEILCLEPAKPSALIPTGANPHCFEITTANVVYYVGENVVNPSSPPPNNSVPP--SGIGTDVARMWEVAIQHALMPVIPKGSSVGSGTNSHKDISVSISVSNSQIQENVDISTVYQIFPDEVLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNLHHPGVVNLECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPFNEDEDIHDQIQNAAFMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKTLSHPWLQDYQTWLDLRELECRIG-ERYITHESDDSRWEQYAGEQG-------LQYPAHLINLSASHG---------------------DSPEAEEREMKALSERVSIL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62101-1", "uniprot_id": "KPCD1_MOUSE", "id": "Q62101-1", "name": "Serine/threonine-protein kinase D1", "aln": "MSVPPLLRPPSPLLPAAAAVAAAAAALVPGSGP--APFPAPGAAPAGGISFHLQIGLSREPVLLLQDSSGDYSLAHVREMACSIVDQKFPECGFYGLYDKILLFRHDPASDNILQLVKIASDIQEGDLIEVVLSAS----ATFEDFQIRPHALFVHSYRAPAFCDHCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVR-RRRLSNVSLTGLGTVRTASAEFSTSVPDEPLLSPVSPGFEQKSPSESFIGREKRSNSQSYIGRPIQLDKLLMSKVKVPHTFVIHSYTRPTVCQFCKKLLKGLFRQGLQCKDCRFNCHKRCAPKVPNNCLGEVTINGELLSPGA-ESDVVMEEGSDDNDSERNS------GLMD---DMDEAMVQDTEMALAEGQSGGAEMQD------------------PDADQEDSNRTISPSTSNNIPLMRVVQSVKHTKRRSSTVMKEGWMVHYTSKDTLRKRHYWRLDSKCITLFQNDTGSRYYKEIPLSEILCLEPAKPSALTPVGATPHCFEITTANVVYYVGENVVNPSSSPPNNSVLP--SGIGPDVARMWEVAIQHALMPVIPKGSSVGSGSNSHKDISVSISVSNCQIQENVDISTVYQIFPDEVLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNLHHPGVVNLECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPFNEDEDIHDQIQNAAFMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKTLSHPWLQDYQTWLDLRELECRIG-ERYITHESDDSRWEQYAGEQG-------LQYPAHLISLSASHS---------------------DSPEAEEREMKALSERVSIL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15139-1", "uniprot_id": "KPCD1_HUMAN", "id": "Q15139-1", "name": "Serine/threonine-protein kinase D1", "aln": "MSAPPVLRPPSPLLPVAAAAAAAAAALVPGSGPGPAPFLAPVAAPVGGISFHLQIGLSREPVLLLQDSSGDYSLAHVREMACSIVDQKFPECGFYGMYDKILLFRHDPTSENILQLVKAASDIQEGDLIEVVLSAS----ATFEDFQIRPHALFVHSYRAPAFCDHCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVR-RRRLSNVSLTGVSTIRTSSAELSTSAPDEPLL--------QKSPSESFIGREKRSNSQSYIGRPIHLDKILMSKVKVPHTFVIHSYTRPTVCQYCKKLLKGLFRQGLQCKDCRFNCHKRCAPKVPNNCLGEVTINGDLLSPGA-ESDVVMEEGSDDNDSERNS------GLMD---DMEEAMVQDAEMAMAECQNDSGEMQD------------------PDPDHEDANRTISPSTSNNIPLMRVVQSVKHTKRKSSTVMKEGWMVHYTSKDTLRKRHYWRLDSKCITLFQNDTGSRYYKEIPLSEILSLEPVKTSALIPNGANPHCFEITTANVVYYVGENVVNPSSPSPNNSVLT--SGVGADVARMWEIAIQHALMPVIPKGSSVGTGTNLHRDISVSISVSNCQIQENVDISTVYQIFPDEVLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNLHHPGVVNLECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPFNEDEDIHDQIQNAAFMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKTLSHPWLQDYQTWLDLRELECKIG-ERYITHESDDLRWEKYAGEQG-------LQYPTHLINPSASHS---------------------DTPETEETEMKALGERVSIL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KHC3-1", "uniprot_id": "A0A0B4KHC3_DROME", "id": "A0A0B4KHC3-1", "name": "Serine/threonine-protein kinase", "aln": "-----------------------------MEGP--------------EVTFLFQFGSVRDAVCVPANS---LTLKTLKDLACDFINTKIPDSGLTYLSERILLFVHDYSTPNVLHIINSAAEVVDETLVEIVLTASPILYPTSEMPTLKPHSLNVHSYKGPTFCDFCGEMLFGLVRQGLKCDGCGQNYHKRCVVKIPNNCNRSNDATSRRSFTLQAPRSPSGSSQQSLVSTEDSTGRN-------DSSSSLNIPGRHQRTHSSGSRNG--------LMVLRIPHTFMVHTYGIPTVCQLCKKLLKGLFKQGLQCRDCQYNTHKKCMDKVPHDCTGEAQLSQLQIQAGAKERDNFFREEFDDSDGDDGSEYGKYKSAMSSGVNLVAGRPREAPKALTNAHNSPPELVNGGLVDDSSVSGGETSKSSSDGQSEQSQSSTSSSPSANIPLMRIVQSVKHTKKRGGQALKEGWLVHYTSLDKAVKRYYWRLDSKTITLFVSEQGSKYHKELPLAELLSIESHLG---DPRPECNYCFELRLPNLSYFVGQDPQVGAKEEQAVRLPPPDSGIGSDIAKSWETSIRQAFMHVT----------------NTQCCESEEQVQD---MGQLYQIFPDEVLGSGQFGVVYGGVHKKTQREVAIKVIDKLRFPTKQEAQLKNEVAILQNISHCGVVNLERMFETPERIFVVMEKLKGDMLEMILSHARGRLSERVTKFLITQILIALKYLHSQNIVHCDLKPENVLLSSDAEFPQVKLCDFGYARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPFNEEEDINDQIQNAAFMYPPNPWKEISSNAIDLINNLLQVKQRKRYTVDKSLLHYWLQDKQTYRDLRNLEAQVGAGRYLTHEADDLRWDCAGDMXPGCEPEAILESTTELISCSANTTTESYRRSPADCAGCHRLSDCGNSPKSEAMSDRALKWMRFHLCRHIK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .** ::* :*:* *:.* : :* :* ::::**.::: *:*:.*: : ::**** ** :: *:*:::: *::: : *:*:**:** .* * ::**:* ****:.*:***.*****:*********:*** ******..******. . ..:* . : :* : .*. *.. :.*.* .: **.:*::*.. . : :::****::*:* ***** *********:*****:**::* **:* ***::* **. :. :..** * * .:.* **.*.: .* . *. :: . ::: *::: :.. *: : .* : *::: : *.*.* ******:********::.. .:****:***** *. **:******* **** .: **:*:**:**:*:*.:*. * :***: .*: *:**:: :. : . **:*.*:*: ** :*::*:* * ... . *: *:*: :. :***************:**** *:** *:****:***********:**:********: * ****** *******:*******:********* :***.*::*********:**::** :**************:* **********:*******************************************************:***:******************* :************ ****:***:* * **** **: ***:**.::* **:***:** **: .. *: .:.**. **. ::*::* . :** * ", "identical_positions": 453, "similar_positions": 222, "identity": "45.8%" }, { "cls_id": "homologset.agr.RGD:620965", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01062-1", "uniprot_id": "PDE2A_RAT", "id": "Q01062-1", "name": "cGMP-dependent 3',5'-cyclic phosphodiesterase", "aln": "-------MVLVLHHILIAVVQFLRRGQQVFLKPDEPPP--QPCADSLQDALLSLGAVIDIAGLRQAAKDALSAVLPKVETVYTYLVDGESRLVCEDPPHELPQEGKIREAVISRKRLSCDGLGPSDLLGKPLARLVAPLAPDTQVLVIPLLDKETGTVAAVILVHCGQLSDSEEQSLQVVEKHALVALQRVQALQQR----RPEAVQNTSADPSEDQKDEKGYTAHDRKILQLCGELYDLDATSLQLKVLRYLQQETQATHCCLLLVSEDNLQLSCKVIGEKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGCELRAMLCVPVISRATDQVVALACAFNKLGGDF----FTDEDERAIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPDLDVTRAPVNGCCSLEG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922S4-1", "uniprot_id": "PDE2A_MOUSE", "id": "Q922S4-1", "name": "cGMP-dependent 3',5'-cyclic phosphodiesterase", "aln": "MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPP--QPCADSLQDALLSLGAVIDIAGLRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIREAVISQKRLSCNGLGPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEKHALVALRRVQALQQR----RPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGDFPTSSFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPVNGCCSLEG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00408-1", "uniprot_id": "PDE2A_HUMAN", "id": "O00408-1", "name": "cGMP-dependent 3',5'-cyclic phosphodiesterase", "aln": "MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTG-CLGQVVEDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDL----FTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : *. ************** ***************:****:**::*.::*******:********:****:***************:***:**:***.*:*** *** ************** ****:** ***:*:**************.** ***.****:****:***.**** *.****.. ..:****. .** :***********:****:*******:******:*::*******************:************ ********:.********:******.******:************************* **: ******:.********.***********************************************************************************************************************************************************************************************************************************.***************************************************************************:******************************************************************************************************************:************************************************************************************************************************************* ****:******:. ", "identical_positions": 844, "similar_positions": 57, "identity": "89.22%" }, { "cls_id": "homologset.agr.RGD:620966", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53349-1", "uniprot_id": "M3K1_MOUSE", "id": "P53349-1", "name": "Mitogen-activated protein kinase kinase kinase 1", "aln": "MAAAAGDRASSSGFPGAAAASPEAGGGGGGGGALQGSGAPAAGAAGLLREPGSAGRERADWRRRQLRKVRSVELDQLPE---QPLFLAAASPPCPSTSPSPEPADAAAGASRFQPAAGPPPPGAASRCGSHSAELAAARDSGARSPAGAEP---------PS-AAAPSGREMENKETLKGLHKMEDRPEERMIREKLKATCMPAWKHEWLERRNRRGPVVVKPIPIKGDGSEVN---NLAAEPQGEGQAG-SAAPAPKGRRSPSPGSSPSGRSVKPESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQNCSCGRGAFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNSHTLSSSSTSTSSSENSIKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELSSPVESPAS----LRAVQQPSSPQQPVAGSQRRNQESSFNLTHFGTQQIPSAYKDLAEPWIQVFGMELVGCLFSRNWNVREMALRRLSHDVSGALLLANGESTGNSGGGSGGSLSAGAASGSSQPSISGD-VVEACCSVLSIVCADPVYKVYVAALKTLRAMLVYTPCHSLAERIKLQRLLRPVVDTILVKCADANSRTSQLSISTVLELCKGQAGELAVGREILKAGSIGVGGVDYVLSCILGNQAESNNWQELLGRLCLIDRLLLEFPAEFYPHIVS-TDVSQAEPVEIRYKKLLSLLTFALQSIDNSHSMVGKLSRRIYLSSARMVTAVPAVFSKLVTMLNASGSTHFTRMRRRLMAIADEVEIAEVIQLGVEDTVDGHQDS----LQAVAPTSCLE---NSSLEHTVHREKTGKGLSATRLSASSEDISDRLAGVSVGLPSS-----TTTEQPKPAVQTKGRPHSQCLNSSPLSHA-QLMFPAPSAPCSSAPSVP-----DISKHRPQAFVPCKIPSASPQTQRKFSLQFQRNCSEHRDSDQLSPVFTQSRPPPSSNIHRPKPSRPVPGSTSK----LGDATKSSMTLDLGSASRCDDSFGGGGNSGNAVIPSDETVFTPVEDKCR-LDVNTELNSSIEDLLEASMPSSDTTVTFKSEVAVLSPEKAEN-DDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIVPQLQVENGEDIIIIQQDTPETLPGHTKAKQPYREDAEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMGHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVAVRCLELQPQDRPPSRELLKHPVFRTTW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62925-1", "uniprot_id": "M3K1_RAT", "id": "Q62925-1", "name": "Mitogen-activated protein kinase kinase kinase 1", "aln": "MAAAAGDRASSSGFPGAAAASPEAGGGG---GALQGSGAPAAG-AGLLRETGSAGRERADWRRQQLRKVRSVELDQLPE---QPLFLTAS-PPCPSTSPSPEPADAAAGASGFQPAAGPPPPGAASRCGSHSAELAAARDSGARSPAGAEP---------PS-AAAPSGREMENKETLKGLHKMDDRPEERMIREKLKATCMPAWKHEWLERRNRRGPVVVKPIPIKGDGSEMS---NLAAELQGEGQAG-SAAPAPKGRRSPSPGSSPSGRSGKPESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQNCSCGRGTFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNCHTLSSSSTSTSSSENSIKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELSSPVDSPTS----LRGVQQPSSPQQPVAGSQRRNQESNFNLTHYGTQQIPPAYKDLAEPWIQAFGMELVGCLFSRNWNVREMALRRLSHDVSGALLLANGESTGTSGGGSGGSLSAGAASGSSQPSISGD-VVEAFCSVLSIVCADPVYKVYVAALKTLRAMLVYTPCHSLAERIKLQRLLRPVVDTILVKCADANSRTSQLSISTLLELCKGQAGELAVGREILKAGSIGVGGVDYVLSCILGNQAESNNWQELLGRLCLIDRLLLEISAEFYPHIVS-TDVSQAEPVEIRYKKLLSLLAFALQSIDNSHSMVGKLSRRIYLSSARMVTTVPPLFSKLVTMLSASGSSHFARMRRRLMAIADEVEIAEVIQLGSEDTLDGQQDS----SQALAPPRYPE---SSSLEHTAHVEKTGKGLKATRLSASSEDISDRLAGVSVGLPSS-----ATTEQPKPTVQTKGRPHSQCLNSSPLSPP-QLMFPAISAPCSSAPSVPAGSVTDASKHRPRAFVPCKIPSASPQTQRKFSLQFQRTCSENRDSEKLSPVFTQSRPPPSSNIHRAKASRPVPGSTSK----LGDASKNSMTLDLNSASQCDDSFGSGSNSGSAVIPSEETAFTPAEDKCR-LDVNPELNSSIEDLLEASMPSSDTTVTFKSEVAVLSPEKAES-DDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIVPQLQVENGEDIIIIQQDTPETLPGHTKANEPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGASVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHPVFRTTW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13233-1", "uniprot_id": "M3K1_HUMAN", "id": "Q13233-1", "name": "Mitogen-activated protein kinase kinase kinase 1", "aln": "MAAAAGNRASSSGFPGARATSPEAGGGG---GALKASSAPAAA-AGLLREAGSGGRERADWRRRQLRKVRSVELDQLPE---QPLFLAAS-PPASSTSPSPEPADAAGSGTGFQPVAVPPPHGAASRGGAHLTESVAAPDSGASSPAAAEPGEKRAPAAEPSPAAAPAGREMENKETLKGLHKMDDRPEERMIREKLKATCMPAWKHEWLERRNRRGPVVVKPIPVKGDGSEMN---HLAAESPGEVQAS-AASPASKGRRSPSPGNSPSGRTVKSESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETNRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQNCSCARGTFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNSHTLSSSSTSTSSSENSIKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELSSPVDSPSS----LRAAQQQTVQQQPLAGS-RRNQESNFNLTHYGTQQIPPAYKDLAEPWIQVFGMELVGCLFSRNWNVREMALRRLSHDVSGALLLANGESTGNSGGSSGSSPSGGATSGSSQTSISGD-VVEACCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERIKLQRLLQPVVDTILVKCADANSRTSQLSISTLLELCKGQAGELAVGREILKAGSIGIGGVDYVLNCILGNQTESNNWQELLGRLCLIDRLLLEFPAEFYPHIVS-TDVSQAEPVEIRYKKLLSLLTFALQSIDNSHSMVGKLSRRIYLSSARMVTTVPHVFSKLLEMLSVSSSTHFTRMRRRLMAIADEVEIAEAIQLGVEDTLDGQQDSF---LQASVPNNYLETTENSSPECTVHLEKTGKGLCATKLSASSEDISERLASISVGPSSSTTTTTTTTEQPKPMVQTKGRPHSQCLNSSPLSHHSQLMFPALSTPSSSTPSVPAGTATDVSKHRLQGFIPCRIPSASPQTQRKFSLQFHRNCPENKDSDKLSPVFTQSRPLPSSNIHRPKPSRPTPGNTSK----QGDPSKNSMTLDLNSSSKCDDSFGCSSNSSNAVIPSDETVFTPVEEKCR-LDVNTELNSSIEDLLEASMPSSDTTVTFKSEVAVLSPEKAEN-DDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIVPQLQVENGEDIIIIQQDTPETLPGHTKAKQPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHPVFRTTW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1Q9-1", "uniprot_id": "A0A8M2B1Q9_DANRE", "id": "A0A8M2B1Q9-1", "name": "Mitogen-activated protein kinase kinase kinase 1", "aln": "-MATAGSRTSSLG--GLLDSSSGTNIGN----GLQGTSNGSTSQNSSGKVKRNAG-ESSQWRR----KVRSVDLDKCESGTAALHFLTVSGPGSIQTALLQQSLADPPLGDKTSNNLCTSAQEWMKSSLKSSSESPSAEHGGAAAAVDVNA--------------SQNSRDMENKETLRGLQKMEDRPEERLIREKLKATCMPTWKSEWLERRSRRGPMVVKPIPLRADGTEAGSDSHNSSSSQSRGQRSPSPGPSSFSAASSSSSSSSTKTAGKPDSPGLRRRRASPVP--SGRVTPPRRAPSPDGFSPYSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKFRVFIGPQTCSCGRGTFCIHVLFVMLRVFQLEPSDPLLWRKTLKNFEVESLFQKYHNRRSSRIKAPSRSTIQKFVSRMSNSHTSCTSSASPSSNESSMKDEEEQMCPICLLDMLDEESLTVCEEGCRNKLHHHCMSIWAEECRRNHDPLICPLCRAKWKPHDFYSYEAPSTVESTTSRSQSQTAASSSSSSSSLHAESSRTGQDGDFSLPQYGVQHIPQTYTELAEPWIKVFGLELVGCLFSRNWNIREMALRRLSHDVSGALLLANGEHS-----------LAGAGAGAGLAEVSGDVVVESCCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSASERTRLQQLLRPVVETILVKCADANSRTSQLSVSTLLELCKGQMGELAVGREILKAGSIGIGGVDYVLNCILGSKTEANNWQALLGRLCLIDRLLLEFPAEFYPHIVSGGDCNQAQNVVERYQKLLPLLSFALKSIDNSHSMVGKLSRRVFLSAARMVARVPHVFVKLLDMLNVTSSTHYARMRRRLLAIAEEMDILDAIHLGLDDLQKEHTSPSCAFLEPSAPHNSPCTTERSSPTHGLQQPAAKVALSGQASSTPVEDITERLSNIVAS----------PAEFPKPPIQARNRPVSQCLNSPSSGQPPSLPSLSMANASAFPPENP--------KALPQSFIPSKFAQSSLGSQRKLPLQKG-ACSSKEPEKLPSPVFTQARPLPQSQIHRPRPSRPTPAASSDGAKALSPLTKGNMKLDLQEARSRDDVACSG---GSALIPSEDTAFTPVEEKFHGLDASADLSSSMEDLLEASIPAADSTVTFQSEVAVLSPEQANANDDTYSEDVTQNQKCKEKMEAEEEEALAVVMAMSESQDALPVIPQLQVDKGEDVIIIQVDTPETLPGHTKAKQPYREGNEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMGLLNHPHIIRMLGATCEKNNYNLFVEWMAGGSVSHLLNKYGAFKEGVIINYTEQLLRGLAYLHENQIIHRDIKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMSCAKPPWNAEKHSNHLALIFKIASATTAPSIPPHLSPGLRDVTLRCLELQPTDRPPSRELLKHPVFRHSW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P27636-1", "uniprot_id": "CDC15_YEAST", "id": "P27636-1", "name": "Cell division control protein 15", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSMADTDRVN-LTPIQRASEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELN----------------------------------------------------------------------------------------DIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGS----------LRRLISRSSTG--LSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGTLNWMAPEILG----------------NRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYP----------PSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWINSTENVKVDKLNKFKEDFTDADYHWDADFQEEKLNISPSKFS----------------------LAAAPAAWAENNQELDLMPPTESQLLSQLKSS------SKPLTDLHVLFSVCSLENIAD-TIIECLSRTTVDKRLITAFGSIFVYDTQHNHSRLRLKFIAMGGIPLIIKFEHLAKEFV--IDYPQTLIECGIMYPPNFASLK-----TPKYILELVYRFYDLTST-----------------AFWCRWCFKHLDISLLLNNIHERRAQSILLKLSSYAPWSFEKILPSLIDS------KLKKKILISP---QITYVVFKSINYMITTNDDK-------------------------IHKSAIPSSSSLPLSSSP------------------------TRNSPVNSVQSPSRSPVHSLMATRPSSP--MRHKSISN----------------------------FPHLTISSKSRLLIELPEGFFT-----WLTSFFVDMAQIKDLSVLKYFTKLCYLTVHIN----------STFLNDLLDN----DAFFAFIRNIDTIIPFIDDAKTAAFIWKQITAICVEMSLDMDQMSASLFSTAMNFIRKKNNTSISGLEIILN---------------------------CLHFTLRNVNDDVAPTVGSSESHSVFLIKVNNDAAIELP---------------------------------------IDQLVDLFYALNDDDVNLSKLISIFTKICSLPGFENLTINIIFHPNFYEKIVSFFDTYFNSLLIQIDLLKF------IKLIFSKSLLKLYDYTGQPDPIKQTEPNR-----------------------RNKATVFKLRAILVQITEFLNNNWNKDVPKRNSNQVGGDSVLICQLCEDIRSLSKKGSLQKVSSVTAAIGSSPTKDERSNLRSSKDKSDGFSVPITTFQT----------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* :.: :. * :: .*: : . :. :: : ..: . :*. : :. * . : *.: **:::. *.:: . :.:.::* : *: . : *::. ..:. * .: *.: .::*: : : .. *: : : : : : : *: .*. :: . : *.* * *: .**: . . * : .: :*: * : . .. : . . . : : : :: :: * ::... : : :.:* *. . ..* ..* :. . . . * : : ..:** : :. .*. *:.:: . .. :: :: * :..*:. *:.. .: . : *.* * :.: :: : .. : :** . * . . *: * : :**: .** : :.:: :* * : . .** :: : .* * *:: * : ::::::: . :* .: . : : . : . *:. . : * :*: .*. :.* :. . : : : :. : :: :: :: :..*.: . .: : .. . ..: ** . * .::** : . *.. : ::. .:::: : :.:: . : :.:.:: . * .: ::: :* :. . .:. :* :: *:. ** : : :: *. * .. : . : :: :* : ::: * :: .. :. .:* :: . : * *: : : :::.**: * : : *:: . : : . :::. *: *: : :. .* :* . . * ::. . . : :::: : .::.: . .:* .. . .: : . : ", "identical_positions": 96, "similar_positions": 387, "identity": "6.23%" }, { "cls_id": "homologset.agr.RGD:620967", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61083-1", "uniprot_id": "M3K2_MOUSE", "id": "Q61083-1", "name": "Mitogen-activated protein kinase kinase kinase 2", "aln": "MDDQQALNSIMQDLAVLHKASRPALSLQETRKAKPSSPKKQNDVRVKFEHRGEKRILQVTRPVKLEDLRSKSKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHM-------KSLKILLVVNGSTQATNLEPSPSPEDLNNTPLGAERKKRLSVVG-----PPNRDRSSPPPGYIPDILHQIARNGSFTSINS------------------EGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFTDYDNPIFEKFGKGGTYP--------RRYHVSYHHQEYNDGRKTFPRARRTQGTSFRSPVSFSPTDHSLSTSSGSSVFTPEYDDSRIRRRGSD--IDNPTLT---------------------VTDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPE----------------------------------SPETSKEVN-----ALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIF-VEAKLRPSAEELLRHMFVHYH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M9D0-1", "uniprot_id": "F1M9D0_RAT", "id": "F1M9D0-1", "name": "mitogen-activated protein kinase kinase kinase", "aln": "MDDQQALNSIMQDLAVLHKASRPALSLQETRKAKPSSPKKQNDVRVKFEHRGEKRILQVTRPVKLEDLRSKSKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHM-------KSLKILLVLNGSTQATNLEPSPSPDDLNNTPLGAERKKRLSVVG-----PPNRDRSSPPPGYIPDELHQIARNGSFTSINS------------------EGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFSDYDNPIFEKFGKGGTYP--------RRYHVSYHHQEYNDGRKTFPRARRTQGTSFRSPVSFSPTDHSLSTSSGSSIFTPEYEDSRIRRRGSD--IDNPTLT---------------------VTDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPD----------------------------------SPETSKEVN-----ALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIF-VEAKLRPSAEELLRHLFVHCH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2U5-1", "uniprot_id": "M3K2_HUMAN", "id": "Q9Y2U5-1", "name": "Mitogen-activated protein kinase kinase kinase 2", "aln": "MDDQQALNSIMQDLAVLHKASRPALSLQETRKAKSSSPKKQNDVRVKFEHRGEKRILQFPRPVKLEDLRSKAKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHM-------KSLKILLVINGSTQATNLEPLPSLEDLDNTVFGAERKKRLSIIG-----PTSRDRSSPPPGYIPDELHQVARNGSFTSINS------------------EGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFSDYDNPIFEKFGKGGTYP--------RRYHVSYHHQEYNDGRKTFPRARRTQGTSLRSPVSFSPTDHSLSTSSGSSIFTPEYDDSRIRRRGSD--IDNPTLT---------------------VMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPD----------------------------------SPETSKEVN-----ALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIF-VEAKLRPSADELLRHMFVHYH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P23561-1", "uniprot_id": "STE11_YEAST", "id": "P23561-1", "name": "Serine/threonine-protein kinase STE11", "aln": "--MEQTQTAEGTDLLIGDEKTNDLPFVQLFLEEIGCTQYLDSFIQCNLVTEEEIKYLDKDILIALGVNKIGDRLKILRKSKSFQRDKRIEQVNRLKNLMEKVSSLSTATLSMNSELIPEKHCVIFILNDGSAKKVNVNGCFNADSIKKRLIRRLPHELLATNSNGEVTKMVQDYDVFVLDYTKNVLHLLYDVELVTICHANDRVEKNRLIFVSKDQTPSDKAISTSKKLYLRTLSALSQVGPSSSNLLAQNKGISHNNAEGKLRIDNTEKDRIRQIFNQRPPSEFISTNLAGYFPHTDMKRLQKTMRESFRHSARLSIAQRRPLSAESNNIGDILLKHSNAVDMALLQGLDQTRLSSKLDTTKIPKLAHKRPEDNDAISNQLELLSVESGEEEDHDFFGEDSDIVSLPTKIATPKNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQE--GGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTN-TTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQHPWLDAHII", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: .: ** : .: :. :* : .: :. :: :: . * : *: : * : :: : :. . . ::.: :: ::*. .* :: * * *::: :**:: .*:: . :.:.: : :: *: . :* . .* : ** : .* :: ..: *. * . * .** * ...*.. : :. :. :. . . :* *.: . * . . .* :* : : *::*. . : * : .::. . ...* :* . ..: ::.: : ::* : . . ** ::: ** . . . :*.** * :*.*:** *** :..**. :*****::. : *:*.:::: **: *::***:* **.** ***. :: .*.**:* ****:.. *: **.: *.: ::***** ** ***.: *:********** * .* :*: *** **:*..: . . *: *: :******:. . ******..*.*:**:* * *:.:*. * *****.*: *.*::*. .:. ::**:: * :: : **** ***:* ::. * ", "identical_positions": 163, "similar_positions": 224, "identity": "22.58%" }, { "cls_id": "homologset.agr.RGD:620968", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02111-1", "uniprot_id": "KPCT_MOUSE", "id": "Q02111-1", "name": "Protein kinase C theta type", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MSPFLRIGLSNFDCGTCQAC----------------------------------------QGEAVNPYCAVLVKEYVESENGQ-MYIQKKPTMYPPWDSTFDAHINKGRVMQIIVKGKNVD---------------------------------------------LISETTVELYSLAERCRKNNGRTEIWLELKPQGRMLMNARYFLEMSDTKDMS-------EFENEGFFALHQRRGAIKQAK--VHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSAINSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTKVANLCGINQKLMAEALAMIEST-----QQARSLRDSEHIFREGPVEIGLPCSTKNETR----PPCVPTP--GKREPQGISWDSPLDGSN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSAGPPEPEVSMRRTSLQLKLKIDDFILHKMLGKGSFGKVFLAEFKRTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA--WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEVILGLQFLHSKGIVYRDLKLDNILLDRDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLVYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEREAKDLLVKLFVREPEKRLG----VRGDIRQHPLFREINWEELERKEIDPPFRPKVKSPYDCSNFDKEFLSEKPRLSFADRALINSMDQNMFSNFSFINPGMETLICS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WTQ0-1", "uniprot_id": "KPCT_RAT", "id": "Q9WTQ0-1", "name": "Protein kinase C theta type", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MSPFLRIGLSNFDCGTCQAC----------------------------------------QGEAVNPYCAVLVKEYVESENGQ-MYIQKKPTMYPPWDSTFDAHINKGRVMQIIVKGKNVD---------------------------------------------LISETTVELYSLAERCRKNNGRTEIWLELKPQGRMLMNARYFLEMSDTKDMS-------EFENEGFFALHHRRGAIKQAK--VHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRRCNAAIHKKCIDKVIAKCTGSAINSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTKVANLCGINQKLMAEALAMIEST-----QQARTLRDSEHIFREGPIEISFPRSIKSETR----PPCVPTP--GKSEPQGICWESPLDGAD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTAQPPEPEVNLQRASLQLKLKIDDFILHKMLGKGSFGKVFLAEFKRTKQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA--WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEVILGLQFLHSKGIVYRDLKLDNILLDRDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEREAKDLLVKLFVREPEKRLG----VRGDIRQHPLFREINWEELERKEIDPPFRPKVKSPYDCSNFDKEFLSEKPRLSFADRALINSMDQNMFSNFSFINPGMETLICS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04759-1", "uniprot_id": "KPCT_HUMAN", "id": "Q04759-1", "name": "Protein kinase C theta type", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MSPFLRIGLSNFDCGSCQSC----------------------------------------QGEAVNPYCAVLVKEYVESENGQ-MYIQKKPTMYPPWDSTFDAHINKGRVMQIIVKGKNVD---------------------------------------------LISETTVELYSLAERCRKNNGKTEIWLELKPQGRMLMNARYFLEMSDTKDMN-------EFETEGFFALHQRRGAIKQAK--VHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSAINSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTKVANLCGINQKLMAEALAMIEST-----QQARCLRDTEQIFREGPVEIGLPCSIKNEAR----PPCLPTP--GKREPQGISWESPLDEVD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KMCHLPEPELNKERPSLQIKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA--WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLG----VRGDIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNFSFMNPGMERLIS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B909-1", "uniprot_id": "A0A8M3B909_DANRE", "id": "A0A8M3B909-1", "name": "Protein kinase C", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MSPFLRIAFSSFEMDPGLAY----------------------------------------HEEVLNPYCAVYMKEAVETEKGQ-VYKQKRPTMYPPWSSTFDAHVHKGRVMHVVVKDKTAE---------------------------------------------LKTEATVQLDTLASRCKKENGKLEIWVELKPQGRLLMEARYFLERSDAAGHGE-GDGETEREKEGVFALHHRRGAIKQAK--VHVVKCHEFTATFFPQPTFCSVCKEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSAVNSKETMIHKERFKIDMPHRFKVYNYMSPTFCEHCGTLLWGLARQGLKCEECGMNVHHKCQKKVANLCGVNQKLMAEALAMIESTQ----QQARSSRDTETVGREGPVSADQPGVIREPSGRLAISPLTPAPPLPRKEHQGISWDSPADGRR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSLEEPEPLYATPR-KEHHKFTIDSFILHKMLGKGSFGKVFLAELKGSGQFFAVKALKKDVVLMDDDVECTMVERRVLSLA--WDHPFLTHLYCTFQTKENLFFVMEYLNGGDLMFHIQTCHRFDLPRSTFYAAEIICGLQFLHSKGIVYRDLKLDNILLDTDGHIKIADFGMCKENIIGEARTCTFCGTPDYIAPEILLGQKYGTSVDWWSFGVLLYEMLIGQSPFHGHDEEELFQSIRTDDPCYPRWLTRDARDILVKLFVREPERRLG----VKGNIRQHPFFRETDWSALEERQVEPPFKPTVKSANDCSNFDKEFINEKPRLSVTDRMMINSMDQSMFENFSFINPIMTRLKSP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P83099-1", "uniprot_id": "KPC4_DROME", "id": "P83099-1", "name": "Putative protein kinase C delta type homolog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MMFTRAQVRKQKTSNSSSQRP----------------------------------------RSSGGSTRHETRYKQSSTSSSGAGSGLSGASGASGARRDQYRDRDHYGKHSFELPRQHSKE---------------------------------------------EAYHRDRESSAGGVDRGERSG-------IGGNGGGVTGGGVYVDRRTRPRS-----------------ITNRRGAIKHQK--THDINGHRFVAKFFRQPTFCAFCNLFLWGFGKQGYQCIICQTVVHKKCHDKLLGKCSGSVFTSASTILLRERFKIDMPHRFKPHTFMSPTFCDHCGSLMGGFFIQGLKCEECDVNCHKKCERLTANLCGVNQKLIVEALNHVKRG-------AREARDS----PSTPPSLNPAYKIEAS-----------------EEHDETSYT--YSQFQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSGRFTAPATVIPR---FKNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALG--TKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDKEILASMDQKQFHGFTYTNPHITLD---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24583-1", "uniprot_id": "KPC1_YEAST", "id": "P24583-1", "name": "Protein kinase C-like 1", "aln": "MSFSQLEQNIKKKIAVEENIIRGASALKKKTSNVMVIQKCNTNIREARQNLEYLEDSLKKLRLKTAQQSQGENGSEDNERCNSKEYGFLSTKSPNEHIFSRLDLVKYDCPSLAQRIQYMLQQLEFKLQVEKQYQEANTKLTKLYQIDGDQRSSSAAEGGAMESKYRIQMLNKALKKYQAINVDFDQFKHQPNDIMDNQQPKFRRKQLTGVLTIGITAARDVDHIQSPMFARKPESYVTIKIDDTIKARTKPSRNDRWSEDFQIPVEKGNEIEITVYDKVNDSLIPVAIMWLLLSDIAEEIRKKKAGQTNEQQGWVNASNINGGSSLASEEGSTLTSTYSNSAIQSTSAKNVQGENTSTSQISTNSWFVLEPSGQILLTLGFHKSSQIERKQLMGGLHRHGAIINRKEEIFEQHGHHFVQKSFYNIMCCAYCGDFLR---YTGFQCQDCKFLCHKKCYTNVVTKCIAKTS--TDTDPDEAKLNHRIPHRFLPTSNRGTKWCCHCGYILPWGRHKVRKCSECGIMCHAQCAHLVPDFCGMSMEMANKILKTIQDTKRNQEKKKRTVPSAQLGSSIGTANGSDLSPSKLAERANAPLPPQPRKHDKTPSPQKVGRDSPTKQHDPIIDKRISLQTHGREKLNKFIDENEAYLNFTEGAQQTAEFSSPEKTLDPTSNRRSLGLTDLSIEHSQTWESKDDLMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHIDLETKQKLDWENKNDFREADLTIDSTHTNPFRDMNSETFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQN-QRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTLTPLPSVLTTSQ-QEEFRGFSFMPDDLDL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :: . .. :. . . . . : . *. : : . : . : .. . . :: :*:*** : * . : *.*. . * : *: * *: *:** *: **** ::: ** ... .* . ::: :**** . ...:* *** :: : **. *.: * :* ..::**:. :: : * :: * .: . . . . . : . . . * : .::.* : :****.****:*:: : : *:* **** :: :.*::.: *::*: *. .**:* :::*:***:..::*.**::.*****:*:* ::. *: **.**:: .*:::*.:*::******:*:** :**::***:*:** :: : :*****:::****: ::* ****:****:*:**: **** * **:*:* :* : * :* : : :: *: :: :*:* .:: :. :** :: : . .:.**: * :* . * . *:: * *: : * *. * .*:: : ", "identical_positions": 154, "similar_positions": 205, "identity": "13.25%" }, { "cls_id": "homologset.agr.RGD:620969", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07174-1", "uniprot_id": "M3K8_MOUSE", "id": "Q07174-1", "name": "Mitogen-activated protein kinase kinase kinase 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEYMSTGSDEKEE--------IDLLIKHLNVSEVIDIMENLYASEEPGVYEPSLMTMYP--DSNQNEERSESLLRSGQEVPWLSSVRYG---------TVEDLLAFANHVSNMTKHFYGRRPQECGILLN-MVISPQN------------GRYQIDSDVLLVPWKLTYRNIGS-------------------------------------------------------------------------------------------------GFVPRGAFGKVYLAQDMKTKKRMACKLIPIDQFKP-------------SDVEIQACFRHENIAELYGAVLWGDTVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHILKGLDFLHSKKVIHHDIKPSNIVFMS-TKAVLVDFGLSVKMTEDVYLP-KDLRGTEIYMSPEVILCRG-HSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPL-EDIAGDCSPGMRELIEAALERNPNHRPKAADLLKHEALNPPREDQPRCQSLDSALFERKRLLSRKELQLPENIADSSCTGSTEESEVLRRQRSLYIDLGALAGYFNIVRGPPTLEYG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63562-1", "uniprot_id": "M3K8_RAT", "id": "Q63562-1", "name": "Mitogen-activated protein kinase kinase kinase 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEYMSTGSDEKEE--------IDLLINHLNVSEVLDIMENLYASEEPAVYEPSLMTMCP--DSNQNKEHSESLLRSGQEVPWLSSVRYG---------TVEDLLAFANHISNTTKHFYRCRPQESGILLN-MVISPQN------------GRYQIDSDVLLVPWKLTYRSIGS-------------------------------------------------------------------------------------------------GFVPRGAFGKVYLAQDMKTKKRMACKLIPVDQFKP-------------SDVEIQACFRHENIAELYGAVLWGDTVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVFMS-TKAVLVDFGLSVQMTEDVYLP-KDLRGTEIYMSPEVILCRG-HSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPL-EDIAGDCSPGMRELIEAALERNPNHRPKAADLLKHEALNPPREDQPRCQSLDSALFDRKRLLSRKELELPENIADSSCTGSTEESEVLRRQRSLYIDLGALAGYFNIVRGPPTLEYG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41279-1", "uniprot_id": "M3K8_HUMAN", "id": "P41279-1", "name": "Mitogen-activated protein kinase kinase kinase 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEYMSTGSDNKEE--------IDLLIKHLNVSDVIDIMENLYASEEPAVYEPSLMTMCQ--DSNQNDERSKSLLLSGQEVPWLSSVRYG---------TVEDLLAFANHISNTAKHFYGQRPQESGILLN-MVITPQN------------GRYQIDSDVLLIPWKLTYRNIGS-------------------------------------------------------------------------------------------------DFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKP-------------SDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVFMS-TKAVLVDFGLSVQMTEDVYFP-KDLRGTEIYMSPEVILCRG-HSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPL-EDIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALNPPREDQPRCQSLDSALLERKRLLSRKELELPENIADSSCTGSTEESEMLKRQRSLYIDLGALAGYFNLVRGPPTLEYG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QJ64-1", "uniprot_id": "A0A8M9QJ64_DANRE", "id": "A0A8M9QJ64-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRPAVNTLTERMEYD-NGNSCIELLLAHIKIEDFIQEAEHFYSVGEVVESGISFEEGFSQEEMDENEETAHDLIKHVQKT---GKVRYG---------TTSDLLDFVNMVSNTPSSSLLDVGREMGVLVNKTDMIIKE------------GHYRIDLDVLLFPWKLTYKPQGP-------------------------------------------------------------------------------------------------GHVPKGSFGKVHLAQDTKTRKRMACKLIPVEHFKP-------------ADVEIQARFRHENIAELYGALLWEQTVHLFMEAGEGGSVLEKLESCGPMREFEIIWVSQQVLRGLEYLHSHNIIHHDIKPSNIVLMS-AKAVLVDFGLTVQMKDDVYVP-RDLRGTEMYMSPELVLCRG-HNTKTDIYSLGTTIIHMMSGSPPWVRRYPRTAYPSYLYIIHKQAPPL-EDIPQSCSPAMRRLLEHALERVPSQRSSATELLNEEALHPSREDQPRCWSLDSALEEGTHPLLRQYSQFSDSTQDSSLY--TEDSGHSKKKGSLYIDLGAFAGYYNLVRGPPSSEYG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01389-1", "uniprot_id": "BCK1_YEAST", "id": "Q01389-1", "name": "Serine/threonine-protein kinase BCK1/SLK1/SSP31", "aln": "MPFLRKIAGTAHTHSRSDSNSSVKFGHQPTSSVASTKSSSKSPRATSRKSIYDDIRSQFPNLTPNSTSSQFYESTPVIEQSFNWTTDDHISAGTLENPTSFTNSSYKNDNGPSSLSDSRKSSGGNSVNSLSFDKLILSWDPTDPDEWTMHRVTSWFKFHDFPESWILFFKKHQLFGHRFIKLLAYDNFAVYEKYLPQTKTASYTRFQQLLKKTMTKNVTNSHIRQKSASKLKSSRSSSESIKSKLKNSKSQEDISNSRSTSESALSPTKSGPSKTDEKNFLHSTSTHQKTKSASSLYRRSFISLRGSSSSNASSAKSPSNIKLSIPARPHSIIESNSTLTKSASPPASPSYPSIFRRHHKSSSSESSLLNSLFGSGIGEEAPTKPNPQGHSLSSENLAKGKSKHYETNVSSPLKQSSLPTSDDKGNLWNKFKRKSQIGVPSPNTVAYVTSQETPSLKSNSSTATLTVQTADVNIPSPSSSPPPIPKTANRSLEVISTEDTPKISSTTASFKETYPDCINPDKTVPVPVNNQKYSVKNFLLDQKFYPLKKTGLNDSENKYILVTKDNVSFVPLNLKSVAKLSSFKESALTKLGINHKNVTFHMTDFDCDIGAAIPDDTLEFLKKSLFLNTSGKIYIKDQMKLQQKPKPAPLTSENNVPLKSVKSKSSMRSGTSSLIASTDDVSIVTSSSDITSFDEHASGSGRRYPQTPSYYYDRVSNTNPTEELNYWNIKEVLSHEENAPKMVFKTSPKLELNLPDKGSKLNIPTPITENESKSSFQVLRKDEGTEIDFNHRRESPYTKPELAPKREAPKPPANTSPQRTLSTSKQNKPIRLVRASTKISRSKRSKPLPPQLLSSPIEASSSSPDSLTSSYTPASTHVLIPQPYKGANDVMRRLKTDQDSTSTSPSLKMKQKVNRSNSTVSTSNSIFYSPSPLLKRGNSKRVVSSTSAADIFEENDITFADAPPMFDSDDSDDDSSSSDDIIWSKKKTAPETNNENKKDEKSDNSSTHSDEIFYDSQTQDKMERKMTFRPSPEVVYQNLEKFFPRANLDKPITEGIASPTSPKSLDSLLSPKNVASSRTEPSTPSRPVPPDSSYEFIQDGLNGKNKPLNQAKTPKRTKTIRTIAHEASLARKNSVKLKRQNTKMWGTRMVEVTENHMVSINKAKNSKGEYKEFAWMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSN--LEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETFNFKSTRLAKFIKSNDKLNSSKLRITSQENKTE-----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . . . . *: : : . .:. . * . : :::.. :..:: ::. . . * .* : : . .: . : * : : . * ** * ::: . : :*:** *:*. : .* : ** * : : ::.. ::*. : * **.: * : **:* **** . :. * : * * :: ::*:** :***: ::*:*:*..*::: . . : ***:: : .: . :*** ::*:**:: : :.:*.**:*** ::.* :*. ** . . . . : *.***: ** * *.::: .:* *.:*. * :**.. . . : :. * . : . : : .:. . ", "identical_positions": 78, "similar_positions": 146, "identity": "5.13%" }, { "cls_id": "homologset.agr.RGD:620970", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63584-1", "uniprot_id": "TMEDA_RAT", "id": "Q63584-1", "name": "Transmembrane emp24 domain-containing protein 10", "aln": "MSGLSGPLSWPGPLLSALLFLFLLGPSSVLGISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDAT-KGKFAFTTEDYDMFEVCFESKGTG--RIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1D4-1", "uniprot_id": "TMEDA_MOUSE", "id": "Q9D1D4-1", "name": "Transmembrane emp24 domain-containing protein 10", "aln": "MSGLFGPLSRPGPLPSAWLFLLLLGPSSVLGISFHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDAT-KGKFAFTTEDYDMFEVCFESKGTG--RIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49755-1", "uniprot_id": "TMEDA_HUMAN", "id": "P49755-1", "name": "Transmembrane emp24 domain-containing protein 10", "aln": "MSGLSGPPARRGPFPLALLLLFLLGPRLVLAISFHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDAT-KGKFAFTTEDYDMFEVCFESKGTG--RIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8SXY6-1", "uniprot_id": "TMEDA_DROME", "id": "Q8SXY6-1", "name": "Transmembrane emp24 domain-containing protein bai", "aln": "-------MAR----AAFIVCLLMACAWSSHAVMFKLSPNTQKCLKEDIQANQLVMGEFEVSDVPG----QIIDYIARDTKGHILSQKEHIT-KGKFSFMSEVYDTYEICFISKVPAHQRGVIQEVSLLTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSDSIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLIE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54837-1", "uniprot_id": "TMEDA_YEAST", "id": "P54837-1", "name": "Endoplasmic reticulum vesicle protein 25", "aln": "-------MQVLQLWLTTLISLVVAVQGLHFDIAASTDPE-QVCIRDFVTEGQLVVADIHSDGSVGD--GQKLNLFVRDSVGNEYRRKRDFAGDVRVAFTAPSSTAFDVCFENQAQYRGRSLSRAIELDIESGAEARDWNKISANEKLKPIEVELRRVEEITDEIVDELTYLKNREERLRDTNESTNRRVRNFSILVIIVLSSLGVWQVNYLKNYFKTKHII-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.: : : : *::: : . ** . . . * . *: *: *.. : . :.:* : :::** .: * : : * : *.*::.:: *. .****:**:*:*:*::::.** ::. :::***.:*****.** ** ***: : * .*..*** **:.:**:*::* ", "identical_positions": 53, "similar_positions": 70, "identity": "23.87%" }, { "cls_id": "homologset.agr.RGD:620971", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08761-1", "uniprot_id": "PROS_MOUSE", "id": "Q08761-1", "name": "Vitamin K-dependent protein S", "aln": "MRVLSARFRVLLACLALVIPVSETNFLSKERASQVLVRKRRANTLFEETMKGNLERECIEELCNKEEAREVFENNPETDYFYPKYLGCLGAFRVGSFHAARQSANAYPDLRSCVKAISDQCDPIPCNEDGYLACQDGQAAFTCFCKPGWQGDRCQYDVNECKDPSNVNGGCSQICDNTPGSYHCSCKRGFAMLPNKKDCKDLDECALKPSVCGTAVCKNIPGDFECECPDGYRYDPSSKSCKDVDECSENMCAQLCVNFPGGYSCYCDGKKGFKLAQDQKSCEGIPVCLSLDLDKNYELLYLAEQFAGVVLYLKFRLPDITRFSAEFDFRTYDSEGIILYAESLDHSNWLLIALRDGKIEVQFKNEFSTQITTGGNVINNGIWNMVSVEELDDSVSIKIAKEAVMNINKLGSLFKPTDGFLDTKIYFAGLPRKVESALIKPINPRLDGCIRGWNLMKQGALGAKEIIEGKQNKHCFLNVEKGSYYPGSGIAQFSIDYNNVTNAEGWQMNVTLNIRPSTGTGVMLALVSG-GTVPFALSLVDSRSGTSQDIVVFVENSVVARLEAVSLCSDQQSQLKCNVNRNGLELWTPLRKDVIYSKDLQRQLAVLDKAMKRTVATYLGGIPDISFSATPVNAFYSGCMEVNINGVQLDLDEAISKHKDIRAHSCPSVRKIQKNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53813-1", "uniprot_id": "PROS_RAT", "id": "P53813-1", "name": "Vitamin K-dependent protein S", "aln": "MRVLSVRFRVLLACLALVLPNSETNFLSKERASQVLVRKRRANTLLEETKKGNLERECIEELCNKEEAREVFENNPETDYFYPKYLGCLGAFRVGAFSAARQSANAYPDLRSCVNAIPDQCDPMPCNEDGYLSCKDGQGAFTCICKPGWQGDKCQFDINECKDPSNINGGCSQTCDNTPGSYHCSCKIGFAMLTNKKDCKDVDECSLKPSVCGTAVCKNIPGDFECECPNGYRYDPSSKSCKDVDECSENTCAQLCVNYPGGYSCYCDGKKGFKLAQDQRSCEGIPVCLSLDLDKNYELLYLAEQFAGVVLYLKFRLPDITRFSAEFDFRTYDSEGIILYAESLDHSNWLLIALREGKIEVQFKNEFSTQITTGGNVINNGIWNMVSVEELDDSVSIKIAKEAVMNINKLGSLFKPTDGFLDTKIYFAGLPRKVESALIKPINPRLDGCIRGWNLMKQGALGAKEIVEGKQNKHCFLTVEKGSYYPGSGIAQFSIDYNNVTNAEGWQINVTLNIRPSTGTGVMLALVSG-DTVPFALSLVDSGSGTSQDILVFVENSVAAHLEAITLCSEQPSQLKCNINRNGLELWTPVRKDVIYSKDLQRQLAILDKTMKGTVATYLGGVPDISFSATPVNAFYSGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVRKIQKNF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07225-1", "uniprot_id": "PROS_HUMAN", "id": "P07225-1", "name": "Vitamin K-dependent protein S", "aln": "MRVLGGRCGALLACLLLVLPVSEANFLSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLVDSTSEKSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVWKKTKNS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****. * .***** **:* **:*****::************:*:*** :***********************:*********** ** :*:.* * *****:**********:**.***.*:*******::*:**:.:*** *******::*::*:********:****** ************* **.**.*******:***:****:******************:****: .****:*:****** *******:****:***************:*** :.***.*:**.:**********************:*:***************:******:*** ******* ******:***.:::*****:*****:*********:.*:**********:*** *.**** :*:*:**:****:****** **************.******** * ***:: ******::.*************** ******:.****::********************* .*****:***** * .****:: ***:* :::*::***:* *:*: .:***.*** **:: :.* :*******:***:** .*******:**:.**********.*********************:********** * ** ", "identical_positions": 524, "similar_positions": 110, "identity": "77.51%" }, { "cls_id": "homologset.agr.RGD:620972", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IMZ0-1", "uniprot_id": "NFIL3_RAT", "id": "Q6IMZ0-1", "name": "Nuclear factor interleukin-3-regulated protein", "aln": "---------------------------------------------------------MQLRKMQAIKKEPASLDPTG-------------------SSDKMLLLN----------------------------------------------SALAEVAEDLASGEDLLLNEGSMGKNKSS--------------------------------------------ACRRKREFIPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLSLKLKFGLISS--TVYAQEIQKLSNSTAVYFQDYQTSKAAVSSYVDEHEPAMVAG---------------SCISVIKHSPQSSLSDVSEVSSVEHTQESPAQG------------GCRSPENKFPVIKQEPVELESFARESREERGAYSASIYQSYMGSSFST-YSHSP--------PLLQVHGSTSNSPRTSEADEGVVGKSSDGEDEQQVPKGPIHSPVELQRVHATVVKVPEVNPSALPHKLRIKAKAMQVKVEALDSEFEGMQKLSSPADALAKRHFDLEKHGASGTAHSSLP--------------PFSVQVTNIQDWSLRSEHWHHKELGGKTQGTFKTG-----------VVEVKDSGYKVSEAENLYLKQG------------VANLSAEVVSLKRFIATQPISASDSR--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08750-1", "uniprot_id": "NFIL3_MOUSE", "id": "O08750-1", "name": "Nuclear factor interleukin-3-regulated protein", "aln": "---------------------------------------------------------MQLRKMQTIKKEPAPLDPTS-------------------SSDKMLLLN----------------------------------------------SALAEVAEDLASGEDLLLNEGSMGKNKSS--------------------------------------------ACRRKREFIPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLSLKLKFGLISS--TAYAQEIQKLSNSTAVYFQDYQTSKAAVSSFVDEHEPAMVAG---------------SCISVIKHSPQSSLSDVSEVSSVEHTQESPAQG------------GCRSPENKFPVIKQEPVELESFAREAREERGTYSTSIYQSYMGSSFST-YSHSP--------PLLQVHGSTSNSPRTSEADEGVVGKSSDGEDEQQVPKGPIHSPVELQRVHATVVKVPEVNPSALPHKLRIKAKAMQVKVEALDSEFEGMQKLSSPADAIAKRHFDLEKHGTSGMAHSSLP--------------PFSVQVTNIQDWSLKSEHWHHKELSSKTQSSFKTG-----------VVEVKDGGYKVSEAENLYLKQG------------IANLSAEVVSLKRFIATQPISASDSR--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16649-1", "uniprot_id": "NFIL3_HUMAN", "id": "Q16649-1", "name": "Nuclear factor interleukin-3-regulated protein", "aln": "---------------------------------------------------------MQLRKMQTVKKEQASLDASS-------------------NVDKMMVLN----------------------------------------------SALTEVSEDSTTGEELLLSEGSVGKNKSS--------------------------------------------ACRRKREFIPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLSLKLKFGLISS--TAYAQEIQKLSNSTAVYFQDYQTSKSNVSSFVDEHEPSMVSS---------------SCISVIKHSPQSSLSDVSEVSSVEHTQESSVQG------------SCRSPENKFQIIKQEPMELESYTREPRDDRGSYTASIYQNYMGNSFSG-YSHSP--------PLLQVNRSSSNSPRTSETDDGVVGKSSDGEDEQQVPKGPIHSPVELKHVHATVVKVPEVNSSALPHKLRIKAKAMQIKVEAFDNEFEATQKLSSPIDMTSKRHFELEKHSAPSMVHSSLT--------------PFSVQVTNIQDWSLKSEHWHQKELSGKTQNSFKTG-----------VVEMKDSGYKVSDPENLYLKQG------------IANLSAEVVSLKRLIATQPISASDSG--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68EL6-1", "uniprot_id": "NFIL3_DANRE", "id": "Q68EL6-1", "name": "Nuclear factor interleukin-3-regulated protein", "aln": "--------------------------------------------------------------MQAIKKEPPCSGPYG-------------------GED-ALVLA----------------------------------------------VALQGTDRDLINHKLSTLP----FKSKST--------------------------------------------SCRRKREFIPDEKKDNLYWERRRKNNEAAKRSREKRRLNDMVLENKLMALGEENASLKAELLSLKLRFGLVSS--AAYAQEVQNISTSTAALYQDFMSPSATKDSYPSDLEPTRLTS---------------SCISVIKHSPHSALSDGSDSSTVT--QGSPLIN------------ISRSPDS----IKQEPLETGRYSKER-----ISPYELYRNYLSSPFPGNFSQPS--------PFLQIARSSSNSPRTSDGDDGAVSKSSDNEDEQQVPKGPVPTRSDSQSVIVSTLKVPDSSASALPHKLRIKARAIQIKVEAIDPDYESSGKSSFPVDMSARRRYQMSQCATPEYIQSSLS--------------PMSFQMTNVQDWNHRPKEWHEDHQEALTSYKYRQCPDSPRPVPNKLIVDLENDSYANSESENLYLKQG------------IEDLSAEVACLKRLISKQQGSVIESTKSTTEIDSS-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMS4-1", "uniprot_id": "Q9VMS4_DROME", "id": "Q9VMS4-1", "name": "", "aln": "MSIVCTLEQKVNFFKAAATTKNLLILKNNTDTNYINNYKQDNPSNNKFPRIQAQSNNSHLQHQQQLQQKLAQLHHYSQQKLSGSDFPYGPRPPTGGKEEKLLLLAPPGKLYPEASVSTAMPEVLSGTPTNSHNKANIAMMNNVRLSNISPTLSMNGSSNEASNLHPLSMYGGSISPQSNDSGMSDSLGKYVPGSGYGDGMMAQSPSQGGNGPQSALTAAQKELFSQRKQREFTPDNKKDESYWDRRRRNNEAAKRSREKRRYNDMVLEQRVIELTKENHVLKAQLDAIRDKFNISGENLVSVEKILASLPTSEQVLSNTKRAKMSGSGGSSSGSSPSGSGSGEGSPQGGHNGYPVGPPLSPLIYGPNGNARPEATVKSVHHIHHAGVAPPPTHLQQLVVPQSQTQHLYQPQPQQHQPHQQQQISQPPQQQQQQQEPSPSAGSSSPVISDPHNRPPSTTIANLQVQLQQALNRNVRPEDLDSLRKVVAAGALYNAAAVVGAPPPPPSAGLYVPAPSAYKDHLEAAAAWSHNVEAAVSSSAVDAVSSSSVSGSAASVLNLSRRACSPSYEHMLSSTTSSTLSSASSSGAVSGDDEQEHEPAHMAPLQLQRSSPQQGSDANNCLPLKLRHKSHLGDKDAAATALLSLQHIKQEPNCSRASPPAWNDGGDNSSDERDSGISIASAEWTAQLQRKLLAPKEANVVTSAERDQMLKSQLERLESEVASIKMILAE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :::: . . : ::* :: .: . . : ... : *::*** **:*** **::**:************* **:***:::: * :** ***:* ::: :*.: .. . : : .:..* . : : : .. . .*: . . :* : :.*:. : .:* : : . :::* : :: . . . :. ..:.. ** . . *. : .*. .: : * * . :. * .:* .*::. . : :.. : . . . . :: .:. ** . * . ::* . : .. . : : .::: . : . * : . . . ::::: : .. * ", "identical_positions": 62, "similar_positions": 150, "identity": "8.5%" }, { "cls_id": "homologset.agr.RGD:620973", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KA94-1", "uniprot_id": "A0A0G2KA94_RAT", "id": "A0A0G2KA94-1", "name": "Tyrosine-protein kinase", "aln": "MGLVSACQTPGSAVWPALSPVLCQHALGQESRDLQWQEKEQQKTEMNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSVLTYYEGR-AEKKYRKGFIDISKIKCVEIVKN--DDGIIPCQNKFPFQVVHDAN---------------------------------TLYIFAPSPQSRDRWVKKLKEEIKN-NNNIMIKYHPKFWADGSYQCCR-------------------------------QTEKLAPG-------------------------------------------CEKYNLFESSIRKTLPPAP------------EIK-RRPPPPIP----PEEE-NTEEIVVAMYDFQATEAHDLRLERGQEYIILEKNDTHWWRARDKYGSEGYIPSNYVTGKKSNNLDQYEWYCRNTNRSKAEQLLRTEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETATSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYDKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDV--LLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRLPRPKLASKYLYEVMLRCWQERPEGRPSFEDLLRTIDELVECEETFGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24604-1", "uniprot_id": "TEC_MOUSE", "id": "P24604-1", "name": "Tyrosine-protein kinase Tec", "aln": "---------------------------------------------MNFNTILEEILIKRSQQKKKTSLLNYKERLCVLPKSVLSYYEGR-AEKKYRKGVIDISKIKCVEIVKN--DDGVIPCQNKFPFQVVHDAN---------------------------------TLYIFAPSPQSRDRWVKKLKEEIKN-NNNIMIKYHPKFWADGSYQCCR-------------------------------QTEKLAPG-------------------------------------------CEKYNLFESSIRKTLPPAP------------EIKKRRPPPPIP----PEEE-NTEEIVVAMYDFQATEAHDLRLERGQEYIILEKNDLHWWRARDKYGSEGYIPSNYVTGKKSNNLDQYEWYCRNTNRSKAEQLLRTEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETATSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYDKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDM--LLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRLHRPKLATKYLYEVMLRCWQERPEGRPSLEDLLRTIDELVECEETFGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42680-1", "uniprot_id": "TEC_HUMAN", "id": "P42680-1", "name": "Tyrosine-protein kinase Tec", "aln": "---------------------------------------------MNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSMLTYYEGR-AEKKYRKGFIDVSKIKCVEIVKN--DDGVIPCQNKYPFQVVHDAN---------------------------------TLYIFAPSPQSRDLWVKKLKEEIKN-NNNIMIKYHPKFWTDGSYQCCR-------------------------------QTEKLAPG-------------------------------------------CEKYNLFESSIRKALPPAP------------ETKKRRPPPPIP----LEEEDNSEEIVVAMYDFQAAEGHDLRLERGQEYLILEKNDVHWWRARDKYGNEGYIPSNYVTGKKSNNLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETTTSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDV--LLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVECEETFGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NFV1-1", "uniprot_id": "A0A8M1NFV1_DANRE", "id": "A0A8M1NFV1-1", "name": "Tyrosine-protein kinase", "aln": "---------------------------------------------MSLPHILEETLIKRSQQKKRTSPLNYKERVFVLTKSKLTYYELR-AEKRFKKGSVDLQRVKCVEIVKN--NTTVIPCQNKYPFQVVYDSS---------------------------------TLYIFAPSNESRSVWVQNIKEEIRN-NPLIADKYHSQFWQEGEWLCCG-------------------------------QVDKLAPG-------------------------------------------CEGYNLFGDVSRKPLPPVPEDQN-------ISCTGRRPPPPPPGETKQEEEEPEEEVVIALYDFEGLEPHDLTLKTGEEYVILEKCEVNWYKARNKEGKQGYIPSNYVTEKASDKLEQFIWFSKNVNRNKAEELLRKEGKEGGFMVRLSSNTGTYTVSLYTKSTSDGAAAIRHYQIKEIHASPKQFYLAEKYIFTSIPELIEYHKHNAAGLVSRLRHAVGDQKREAPTTAGFSYDKWEINPSELTFMKELGSGQFGVVRLGKWRAQHKVAIKTIREGAMSEDDFIEEAKIMMNLSHRNLVQLYGVCTQQKPIYLVTEFMELGCLLNFLRQRRGTLAAQD--LLGICHDISQGMQHLEENRFIHRDLAARNCLVNSSMVVKVSDFGMTRYVLDDQYWSSSGTKFPVKWSPPEVFNFCRYSSKSDVWSFGVLMWEVFTEGKMPFEHSQNHEVVLMVTQGHRLYRPKKAAPHIYNIMKMCWMEKPDERPTFSETSLMITNELEDDGSVS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08630-1", "uniprot_id": "BTKL_DROME", "id": "P08630-1", "name": "Tyrosine-protein kinase Btk", "aln": "--------MMGTKHRNSHVNGSIKSSSSLRSSSKSFQAKMDLMSERLYDVVKSGSMVKRAQNKKRFTPVNYKHRWFELTKRTFSYFDVENVERRRERGRIHLKGVRLVEEATVSGEGGDPFAPDGYPFQVGYCEISASANSHQLENGNGGGSGVGIEGQQSGRAVPQYTLYVIANSEKERSEWIRAIRQVCEDSNTPKSYRYHPGLWSGKKWSCCKGLSRTTFGCRAAAHWREANNNPSNGSSPAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQSSLTTFKQSPTLLNGNGTLLDANMPGGIPTPGTP-NSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGYIPSNYVKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTKGLYTLSLHTKVP---QSHVKHYHIKQNAR--CEYYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPCDR--PVPPTAGLSHDKWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALVAQTLTD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::**:*:**: : :***.* *.* ::*:: . .*:: .:* :.:. :: ** .. : . : :**** : ***::* * :.*. *:: ::: .: * :**. :* .: ** .. .::*. * .* . ..: * . *.* * ::: ::*:*:* *:. * ** *: . ** :::. : :*::.:: *. ********. * *::: *: : .*.:**.**: .*** *:** ** * **:**:** : .:**:**: ::**:**: :**::*:**:**:.**. **: . : .*.***:*::****:* ** :*.***** ***** ****.. ..*:* ::**:*.*:*******:* :* * :********::::***:***:*: *.***:**::. : : **.:* ::.:** :**.: :************.. ****:***::******** **.*:***:**.****:*: *:*******::******:** *:**: : * *** * :* * :** .: :*::* ** . *: **:: : : ", "identical_positions": 248, "similar_positions": 198, "identity": "30.81%" }, { "cls_id": "homologset.agr.RGD:620975", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63665-1", "uniprot_id": "USF2_RAT", "id": "Q63665-1", "name": "Upstream stimulatory factor 2", "aln": "MDMLDPGLDPASSATAAAAASHDKGPEAEEGVELQEGGDGPG------AEEQTAVAIASVQQAAFGDHNIQYQFRTESN----GGQVTYRVVQVTDGQLDGQGDAAGAVSVVSTAAFAGGQQAVTQVGVDGAAQRPG-------PAAASVPTGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTAVSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTR-----TPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCHADNSKTGAS---------------------------------KGGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLR------------AQLQQHN-------------------LEMVGESTRQ--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64705-1", "uniprot_id": "USF2_MOUSE", "id": "Q64705-1", "name": "Upstream stimulatory factor 2", "aln": "MDMLDPGLDPASSATAAAAASHDKGPEAEEGVELQEGGDGPG------AEEQTAVAIASVQQAAFGDHNIQYQFRTESN----GGQVTYRVVQVTDGQLDGQGDAAGAVSVVSTAAFAGGQQAVTQVGVDGAAQRPG-------PAAASVPTGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTAVSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTR-----TPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCHADNSKTGAS---------------------------------KGGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLR------------AQLQQHN-------------------LEMVGESTRQ--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15853-1", "uniprot_id": "USF2_HUMAN", "id": "Q15853-1", "name": "Upstream stimulatory factor 2", "aln": "MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPG------AEEQTAVAITSVQQAAFGDHNIQYQFRTETN----GGQVTYRVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQVGVDGAAQRPG-------PAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTAVSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTR-----TPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGAS---------------------------------KGGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLR------------AQLQQHN-------------------LEMVGEGTRQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W4J8-1", "uniprot_id": "Q9W4J8_DROME", "id": "Q9W4J8-1", "name": "", "aln": "---MNVHKRPRLNMEFGSSTSNTNTSTSPSSVNISNANPTAGPGLMTITNHHTADLSEALVHSSFANGQQSLILTSDTGNPLMNSQGAQIFLTICGDENSDDSQEYYTIKQEPGCDLDIHSLLPSNLQLPNNLQLPTGCEIYLVKETGSLMGEPPTKAAIKLELDTLSEKPLLPSVTTSSSTQSAVITAQTVNPPIPGNINTTTSTTSTTTTTSVLYGSHGNGHGHGHAHAQARSQPESAGQTPSSKLEAYKKRDDKRRATHNEVERRRRDKINSWIFKLKEMLPSLSSSSSFSEASTSPSTSGSTSTNGSSHSKGNASSSSGRAPPNDSKSQILIKACEYIKSMQGEIDTLRDCLRETDSLRASNQALREELDRLKRQQQLQERFHTAGGRSTFNVTLNSLNSSATSDLFEGIDTTPNLAAVSSLGFGKRGLLISDFDE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * . .:::*: : . : ..*::.:.. .* ::.:** :: :::*.: : . : :::. ..* : .: : ..: ..:.: ::. . . : . ::: : . * * :.*: *.: .: : :.:*: .: :.*..:: * :.*.:*. . . .::** .: .: *: .:. : : .*::* *. : . **::*** *************.**.:*.:::*. :..* : ** *. ** ***:**:.:: : ::: ::*:: *: .*: **::::.**.:: * . . *:. * :. :* ..* ", "identical_positions": 68, "similar_positions": 158, "identity": "15.45%" }, { "cls_id": "homologset.agr.RGD:620976", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VFG1-1", "uniprot_id": "Q9VFG1_DROME", "id": "Q9VFG1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-------------------------------------------------------------------------------------------MAMDFDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVP-DHWCYHEQLENRSYAE---------------------IAAIYAPF-KRPSCTRLASINMDGSNATASS-EPCNRWIYHYD-HGFISMNADLNWVCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSATIFAETLLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGLGMICASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVSEADYELFRQHCKTKESEA----RSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSI-SPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTG-ILLA-FWTQHSATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLD-TYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGEEFGKGERMFDFMRSFKKADQHDLSADTIEKLMGDKRTY---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFG2-1", "uniprot_id": "Q9VFG2_DROME", "id": "Q9VFG2-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFEEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFVP-DHWCYHEQLENRSFAE---------------------IEKIYSQF-EKPSCTRLEKIDEDGQNHTLSR-ERCNRWIYKYD-FGYKSMNTELNWVCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILANWCGFLGDFSTIFAGSLTSFSISRFISGLAADANSYLMYILILEYVSPSLRNVGLNTVLGSFYCLGLIGACWLAVWVGHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAKINRRQVADKDFKDFRIYCEQHYRKD----KNQE---EHAKLLDMLKTPRMRSTAFKLLLIFIIIVPCYNTIARNVEGLGI-SPFIMFSLNALTLPPSGYLQGLLQDRMGRKATAVGWMAITGIFAVAAG-LVIS-QGSNRNVLLLVGLTMAARFGVSIADGASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPYILHLG-TYYKPAPSIILGLLFLSGAYVCLLLPETRNKKLPMSLAEGEEFGRGEGIFDFLRHMFRREGSKSEVEMGPTIVEEDTLINKPV-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFG0-1", "uniprot_id": "Q9VFG0_DROME", "id": "Q9VFG0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVP-QHWCYHEALENRSFEE---------------------IAAIYAPFGKEASCTRLDKIE--GDRVTVSN-ETCQRWIYNYD-FGFRSMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLAGNWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKLS----NQPE---QTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGL-SPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALG-VALSTEGAQKNVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLG-TKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGEAFGKGESMLSFDCWRRHDDDVSKEATEEVRLHQLNGQTKSETEAEV-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV5-1", "uniprot_id": "Q9VDV5_DROME", "id": "Q9VDV5-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVP-DHWCYHDKLVNMTYKE---------------------IGEIYAQF-ENPSCTRLDDIN--GHNVTVSS-KACEKWIYNYD-FGYRSMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKSVATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQMTHEML----GGDD--KKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGI-SPFIMFSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAG-IAIAYQQHNHNAILLACLTIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLG-TFFKAAPSIILGVLFFAGSFVCLLLPETLNRSLPTTIEEGEVFGKGERMFDFPCLHNKHDDEESESELEKYKRKHSLIDAKQMQMESCSNGKRKQSLIDADHEEQALKDANH------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV9-1", "uniprot_id": "Q9VDV9_DROME", "id": "Q9VDV9-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------MLEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVP-KYWCADGLP-----------------------------ASIESPV--DSSCLPL-------NRNISTP-NTCYSYNYELY-MGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKCSQQNQ----KASP------HLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGI-SPFVMFSLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTR-SVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTSLEDGENFGKNDRWYTFSFLEGRTQSAATLDTQNAKMYSQSTESAVYF-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV8-1", "uniprot_id": "Q9VDV8_DROME", "id": "Q9VDV8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTP-SHRCSRP-----------------------------------EDYQPNSTSLLSCSVMQFDKEF------KCTSWDFERE-SNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLN------NSQNK--SSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGI-SPFKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVGAIITAATG-YLVATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLG-TFYKPLPSLMISFILLIGACLCLALPETLHKNLPQNLEEGEMFAKGEKWYFFPCFSRRPKTQKSATQLESSDGITNKL----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV7-1", "uniprot_id": "Q9VDV7_DROME", "id": "Q9VDV7-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDLQRVLEKCGNFGPYQILLLGLYGYTNIVSSLHYFSQTLISFTP-SHRCSAPV----------------------------------EEFSQNFTELLSCSVIQYDVDMTSFRDNKCSSWDFDKE-SNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPMFSFTRFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYSIGLMISPWIAIWLGNWRSYLWAASLPALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVEDSVFDEFIKHYREKLN------SAQKK--SSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGI-SPFKLFSYSGFVVLPGGLSIILFQNKIGRKGMACASLLVGAFITATTG-YLVGTLDPANYSVLLGFMVCLARFGAVVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYLG-TFYKPLPSLLISFLLIIGACLCLTLPETLHKQLPQTLEEGEIFAKGEKWYFFPCFSRKRQSNKSESQLESANEITK------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDW0-1", "uniprot_id": "Q9VDW0_DROME", "id": "Q9VDW0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTP-EHWCFHADLNGLSVEG---------------------IRSVYENISASSCTPLLGVVNGTGVVSTN---RKCRNWIFNRE-SGYESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYRERELQD----YKLNS--HEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGT-SPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATG-FMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIYLA-QYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKFALNESFLYFPCFS-RKEKNVRTESV--------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV6-1", "uniprot_id": "Q9VDV6_DROME", "id": "Q9VDV6-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFDRVLEKCGNFGRFQFVILILYGYTNILSSLHYFSQTLITFTP-EHWCSHDDLMGLGAAE---------------------LRSIYSNVSHPSCTLLSEVINGTGVASE----ESCQDWIFERE-NGYESLTTELKWVCDKSHQPAVGQSFFFLGSVVGTISFGFLSDHIGRLPAMLMAALSGATGDFITSFVHTLPWFAFSRFVSGLSTDTMYYLMYILVFEYLSPKRRTFGLNIILAVFYCFGLMTSPWIAMWIGNWRRYLWLASLPALGVLIYPLLICESAQWLLTKKKYDEAVACLKKVAKFNGRQVEDSVFDEFVKHYREKMNEE----SKLNK--QMDTFLGMFKTPRLRRFTTTLLVKSVIITLSYDVINRNMEGLGS-SPFKLFSLTSSVYLPAGFTILLLQNKIGRKGMACGALLVGAIITAVTG-FLIAVLDPSENAVLLALMVGLGRFGTTVSYDAEIQYAAEIIPTSVRGQAVSNIHVVGLASSSLAFYVIYLA-QYYKPLPSIFISVLMFLGALLCLTLPETLHKKLPETLADGERFAMNESCLYFPCLHKRRESLTEHEDRKSEP----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8I6ANT8-1", "uniprot_id": "A0A8I6ANT8_RAT", "id": "A0A8I6ANT8-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MAFQELLNQVGGLGRFQILQMVFVVFTSVIVVPHIIIENFTAAIP-SHRCWVPILDNVTVSDNDSRILNQDKLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTFSSITEPDTEPCVDGWVYDRS-NFHSTTVTEWNLVCESQALNSVTKLSFMIGAFIGGIVNGLLSDRFGRKFILKYALLQMAITETCAGFAPNLFIYCSLRFLAGMSLEPITVNINLLMFEWTSPKFLTMVTVLGSCAG-SFGGMILAGLAFQFQNWHHLQLAMSVPIFFFLILTRWLSESARWLIVINKPQKGLKELKKVAHINGMKKSGDNITMEVVRTSMKKELE----AAKMR----PSPRDLFHTPILRKQIYILSFIRLLFILSGVGVAIHLQHLSN-NIELLQILISVSSILFSVIGHFVLNHIGRRITQMVIMFLRGIS------ILTAIFAPQEMETLRFIMAMMAEGLAALSYAANSLHANELLPTTLRATARGVIGMFGNIGFFLAPLCMMLA-SYSPNLPWIFYGGFAILSGFIVLLLPETKNNPLPDCTHDVENDWKE------SRQEMKEDPIIKVTRF--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q76M72-1", "uniprot_id": "S22AR_MOUSE", "id": "Q76M72-1", "name": "Solute carrier family 22 member 27", "aln": "---------------------------------------------------------------------------------------------MSFQELLNQVGSLGRFQILQIVFLLLLNAIVVPHIAMENFTAAIP-NHRCWVPILDNDTASDNGSRILSQDDLLRISIPLDSNLRPEKCRRFAQPQWHLLHLNGTFSNVSEPDTEPCVDGWVYDRS-NFLSTIVTEWDLVCESQALNSVTKFSFMIGLFIGGIICGHLSDRLGRKFILTCALLQFAITETCVAFAPSFFIYCSLRFLAGLSVEPILVNSHLLMLEWTSPKFLTMMAALLSCAP-NIGYMISAGLAFLFRIWHHLQLTMSVPIFFFLILTRWLSESARWLIVTNKPQKGLKELRKVAHMNGMKNSGD-LTMEIVRTSMKAELE----AAKTK----PSLRDLFHTSILRKRICVLSFMRLFFTVSIFGLAVHLQHLSS-NIILLQFLISALAILVSVIGPFVLNHIGRRITYLVLMSLRGIF------ILIAVFVPQEMQTLRIIMATLAEGISSLCVGVSRLHTNELLPTTLRATAVGVIGFFGNSGSFLSPLFMLLA-TYYANMPWIFYGGFSIFNAFTVFLLPETKNQPLPDSTHDVGNDWKE------SRKGKKEDPIIKVTRF--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVM8-1", "uniprot_id": "S22A9_HUMAN", "id": "Q8IVM8-1", "name": "Organic anion transporter 7", "aln": "---------------------------------------------------------------------------------------------MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIP-GHRCWVHILDNDTVSDNDTGALSQDALLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGWVYDRI-SFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGMCPS-GIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELE----AAQKKK---PSLCEMLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGN-NVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAIC------LLAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFANIAGALAPLMMILS-VYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQDEKNERKD------PREPKQEDPRVEVTQF--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VRR0-1", "uniprot_id": "Q9VRR0_DROME", "id": "Q9VRR0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MANDEKGNASTEDDDKPKKREHRDQGQQSKLKKIKYYIEPDKVDIGIQAGDSLEKVKVTYVEPDDEESSHGFFWGKKKSETSLPRRSWETDDYIDFDDLLPMIGQFGRFQIRLFLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPELLHTPVELRKELSIPKEK---------DGSYSRCRMYNTNYTKIHFAENPSAYINTSLPTIPCKKGYVFEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFEASCTQFYKEE----LDGRD----FTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLDSENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLG--------ASFQNRANMRMSALAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLS-KKSLSSTLIVLGALGIFGGLLALFLPETLNHELPETLSDGAQFGKNQRIWHMPCCGPGSRKSHPRHNWHQGSSLRTLSKDEFRSSKMYRKTKYRFESHPSPSSSDYKGTEEKEIRTYKYGNGSKWPEDKS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCA0-1", "uniprot_id": "Q9VCA0_DROME", "id": "Q9VCA0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "------------------------------------------------------------------------MTQSTENPEKNRELISEESMKDLLTKQLEVVGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWTHAQKREIVAKG----LDSGGCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMS-IAFSASYPVGMIILAIVGYVIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQVASDKKSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSV-SRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVS------LLLVLAVPAGSTTWIVAFAMLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCVLVAGLLTLTLPETGTGKLSDKVESSAS-------------STPTEPAEKQ-----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * : . * * . : : * : : * * : * :.* ** : * * :: * : . *: :: . : ** .**: : * : . :. . .*: .. *: ** :: . . . : : . . : . : *.** * . ", "identical_positions": 28, "similar_positions": 48, "identity": "3.83%" }, { "cls_id": "homologset.agr.RGD:620977", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7P1-1", "uniprot_id": "STX12_RAT", "id": "G3V7P1-1", "name": "Syntaxin-12", "aln": "------------------------------MSYGPLDMYRNPGPSGPQPRDFNSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQEN-LQQFQHSTNQLAKETNELLKELGS----LPLPLSASEQRQQKLQKERLMNDFSSALNNFQVVQRKVSEKEKESIARARAGSRLSAEDRQREEQLVSFDSHEEWNQMQSQEEEAAITEQD----------LELIKERETAIQQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERASDQLQRAAYYQKKSRKKMCILVLVLSVIVTVLVVVIWVASK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER00-1", "uniprot_id": "STX12_MOUSE", "id": "Q9ER00-1", "name": "Syntaxin-12", "aln": "------------------------------MSYGPLDMYRNPGPSGPQPRDFNSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQEN-LQQLQHSTNQLAKETNELLKELGS----LPLPLSASEQRQQKLQKERLMNDFSSALNNFQVVQRKVSEKEKESIARARAGSRLSAEDRQREEQLVSFDSHEEWNQMQSQEEEAAITEQD----------LELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATDQLQRAAYYQKKSRKKMCILVLVLSVIVTVLVVVIWVASK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Y82-1", "uniprot_id": "STX12_HUMAN", "id": "Q86Y82-1", "name": "Syntaxin-12", "aln": "------------------------------MSYGPLDMYRNPGPSGPQLRDFSSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQEN-LQQLQHSTNQLAKETNELLKELGS----LPLPLSTSEQRQQRLQKERLMNDFSAALNNFQAVQRRVSEKEKESIARARAGSRLSAEERQREEQLVSFDSHEEWNQMQSQEDEVAITEQD----------LELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKKMCILVLVLSVIILILGLIIWLVYKTK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5F7-1", "uniprot_id": "A0ACD6B5F7_DANRE", "id": "A0ACD6B5F7-1", "name": "Syntaxin-12", "aln": "MIVCFLSIHFDFCERSSASPPHLSITVTVIMSYGMMDSS----HSQSQPRDFNNLTQTCSSNIQKITQNTGQIKSMLFQLGTRPDTPELQDR-LQQVQHYTNQLAKETNRHLKDLGT----LPQPQSPSEQRQQRIQKDRLMNDFSAALNNFQVVQRRAAERERESVARARAGSRFQVDELNQDEQLVTFEKNEGW-RMQTEEE--PVTEED----------LELIKERETNIRQLESDIMDVNQIFKDLAVMIHDQGDMIDSIEANVESAEVHVERGAEQLQHAAYYQRKSRKRMCILALVLSLVATIFAIIIWQAIR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32854-1", "uniprot_id": "PEP12_YEAST", "id": "P32854-1", "name": "Syntaxin PEP12", "aln": "--------------------------MSEDEFFGGDNEAVWNGSRFSDSPEFQTLKEEVAAELFEINGQISTLQQFTATLKSFIDRGDVSAKVVERINKRSVAKIEEIGGLIKKVNTSVKKMDAIEEASLDKTQIIAREKLVRDVSYSFQEFQGIQRQFTQVMKQVNERAKES--LEASEMANDAALLDEEQRQNSSKSTRIPGSQIVIERDPINNEEFAYQQNLIEQRDQEISNIERGITELNEVFKDLGSVVQQQGVLVDNIEANIYTTSDNTQLASDELRKAMRYQKRTSRWRVYLLIVLLVMLLFIFLIMKL-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : .: :*..: : :.:: .*. . ::.: * : * .:. . :::.:: : :* . :*.:.: : ..* :: * : :::*:.*.* ::::** :**: :: :: **: . :...: .: *: :..: : : *.* :**::*: * ::* .* ::*::****. ::::** ::*.****: ::. :.: .:::*::* **::: : * :** :: .: ::: ", "identical_positions": 46, "similar_positions": 122, "identity": "14.33%" }, { "cls_id": "homologset.agr.RGD:620978", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35476-1", "uniprot_id": "OPSG_RAT", "id": "O35476-1", "name": "Medium-wave-sensitive opsin 1", "aln": "-----MAQQLTGEQTLDHYEDSTQASIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSTWMILVVIASVFTNGLVLAATMRFKKLRHPLNWILVNLAVADLAETIIASTISVVNQIYGYFVLGHPLCVIEGYIVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLATVGIVFSWVWAAVWTAPPIFGWSRYWPYGLKTSCGPDVFSGTSYPGVQSYMMVLMVTCCIFPLSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVFAYCLCWGPYTFFACFATAHPGYAFHPLVASLPSYFAKSATIYNPIIYVFMNRQFRNCILQLFGKKVDDSSELSSTSKTEVSSVSSVSPA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35599-1", "uniprot_id": "OPSG_MOUSE", "id": "O35599-1", "name": "Medium-wave-sensitive opsin 1", "aln": "-----MAQRLTGEQTLDHYEDSTHASIFTYTNSNSTKGPFEGPNYHIAPRWVYHLTSTWMILVVVASVFTNGLVLAATMRFKKLRHPLNWILVNLAVADLAETIIASTISVVNQIYGYFVLGHPLCVIEGYIVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLATVGIVFSWVWAAIWTAPPIFGWSRYWPYGLKTSCGPDVFSGTSYPGVQSYMMVLMVTCCIFPLSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVFAYCLCWGPYTFFACFATAHPGYAFHPLVASLPSYFAKSATIYNPIIYVFMNRQFRNCILHLFGKKVDDSSELSSTSKTEVSSVSSVSPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DN77-1", "uniprot_id": "OPSG2_HUMAN", "id": "P0DN77-1", "name": "Medium-wave-sensitive opsin 2", "aln": "MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSSVSPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DN78-1", "uniprot_id": "OPSG3_HUMAN", "id": "P0DN78-1", "name": "Medium-wave-sensitive opsin 3", "aln": "MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSSVSPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04001-1", "uniprot_id": "OPSG_HUMAN", "id": "P04001-1", "name": "Medium-wave-sensitive opsin 1", "aln": "MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSSVSPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04000-1", "uniprot_id": "OPSR_HUMAN", "id": "P04000-1", "name": "Long-wave-sensitive opsin 1", "aln": "MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSSVSPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W6A7-1", "uniprot_id": "OPSR1_DANRE", "id": "Q9W6A7-1", "name": "Red-sensitive opsin-1", "aln": "MAEHWGDAIYAARRKGD---ETTREAMFTYTNSNNTKDPFEGPNYHIAPRWVYNVATVWMFFVVVASTFTNGLVLVATAKFKKLRHPLNWILVNLAIADLGETLFASTISVINQFFGYFILGHPMCIFEGYTVSVCGIAALWSLTVISWERWVVVCKPFGNVKFDAKWASAGIIFSWVWAAAWCAPPIFGWSRYWPHGLKTSCGPDVFSGSEDPGVQSYMVVLMITCCIIPLAIIILCYIAVYLAIHAVAQQQKDSESTQKAEKEVSRMVVVMIFAYCFCWGPYTFFACFAAANPGYAFHPLAAAMPAYFAKSATIYNPVIYVFMNRQFRVCIMQLFGKKVDDGSEVS-TSKTEVS---SVAPA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8AYN0-1", "uniprot_id": "OPSR2_DANRE", "id": "Q8AYN0-1", "name": "Red-sensitive opsin-2", "aln": "MAE-WANAAFAARRRGD---ETTRDNAFSYTNSNNTRDPFEGPNYHIAPRWVYNVATVWMFFVVVASTFTNGLVLVATAKFKKLRHPLNWILVNLAIADLGETLFASTISVINQVFGYFILGHPMCIFEGYTVSVCGIAGLWSLTVISWERWVVVCKPFGNVKFDGKWASAGIIFSWVWAAVWCAPPIFGWSRYWPHGLKTSCGPDVFGGNEDPGVQSYMLVLMITCCILPLAIIILCYIAVFLAIHAVAQQQKDSESTQKAEKEVSRMVVVMILAFCLCWGPYTAFACFAAANPGYAFHPLAAAMPAYFAKSATIYNPIIYVFMNRQFRVCIMQLFGKKVDDGSEVS-TSKTEVS---SVAPA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..: * ::*: *:*****.*:.***************::::.**::** **.*******.** :****************:***.**::*****::**. ***:****:*::*** **:***:.****::******:*********:**.* * .** ***:*** * ************:***********.*.. *******:***:**** **:**:***: *:***:***:***:***********:******::*:*.*****: *****:*:***.**** *::*::**********:********** **::********.**:* :****** **:**", "identical_positions": 252, "similar_positions": 75, "identity": "69.23%" }, { "cls_id": "homologset.agr.RGD:620979", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z330-1", "uniprot_id": "DNMT1_RAT", "id": "Q9Z330-1", "name": "DNA (cytosine-5)-methyltransferase 1", "aln": "MPARTAPARVPALASPAGSLPDHVRRRLKDLER--DGLTEKECVKEKLNLLHEFLQTEIKSQLCDLETKLHKEELSEEGYLAKVKTLLNKDLCLEN--GTLSLTQKANGCPANGSRP---TWKAEMADSNR----SPRSRPKPRGPRRSKSDSETM-IEASSSSVATRRTTRQTTITSHF-KGPAKRKPKEDSEKGNANESAAEE-RDQDKKRRVAGTESRASRAGESVEKPERVRPGTQLCQEEQGEQEDDRR-PRRQTRELASRRKSREDPDREARPGTHLDVDDDDEKDKRSSRPRSQPRDLATKRRPKE-EVEQITPEPPEGKDEDEREEKRRKTTRKKPEPLSIPVQSRVERKASQGKASAIPKLNPPQCPECGQYLDDPDLKYQQ-HPVDAVDEPQMLTNEALSVFDSNSSWFETYDSSPMHKFTFFSVYCSRGHLCPVDTGLIEKNVELYFSGVAKAIHEENPSVEGGVNGKNLGPINQWWISGFDGGEKALIGFSTAFAEYFLMEPSPEYAPIFGLMQEKIYISKIVVEFLQSNPDAVYEDLINKIETTVPPSAINVNRFTEDSLLRHAQFVVSQVESYDDAKDDDETPIFLSPCMRSLIHLAGVSLGQR------RATRRTVINSAKVK--RKGPTKATTTKLVYQIFDTFFSEQIEKDDKEDKENTMKRRRCGVCEVCQQPECGKCKACKDMVKFGGTGRSKQACLKRRCPNLAVKEADEDEEADD-DIPELPSPKKLHQGKKKKQNKDRISWLGEPVKIEENRTYYWKVSIDEETLEVGDCVSVIPDDPSKPLYLARVTALWEDKNG-QMFHAHWFCAGTDTVLGATSDPLELFLVGECENMQLSYIHSKVKVIYRGPSPNWAMEGGMDPEAMLPGAEDGKTYFYQFWYSQDYARFESPPKTQPAEDNKHKFCLSCIRLAELRQKEMPKVLEQLEEVDG--RVYCSSITKNGVVYRLGDSVYLPPEAFTFNIKMASPMKRS-KRDPVNENPVPRDTYRKYSDYIKGSNLDAPEPYRIGRIKEIYCGKKKGGKVNEADIKIRLYKFYRPENTHKSIQATYHADINLLYWSDEEAVVDFSDVQGRCTVEYGEDLLESIQDYSQGGPDRFYFLEAYNSKTKSFEDPPNHARSPGNKGKGKGKGKGKGKPQVS--EPKEPE-AAIKLPKLRTLDVFSGCGGLTEGFHQAGISETLWAIEMWEPAAQAFRLNNPGTTVFTEDCNVLLKLVMAGEVTNSLGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFRRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITMRDTMSDLPEIQNGASAPEISYKWRATVLVPEAAARVALPAHPQGPYPQVHERAGGCRMRHIPLSPGSDWRDLPNIQVRLRDGVITNKLRYTFHDTKNGCSSTGALRGVCSCAEG-KTCDPASRQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDRHRQVGNAVPPPLAKAIGLEIKLCLLASAQESASAAVKGKEETTTED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13864-1", "uniprot_id": "DNMT1_MOUSE", "id": "P13864-1", "name": "DNA (cytosine-5)-methyltransferase 1", "aln": "MPARTAPARVPALASPAGSLPDHVRRRLKDLER--DGLTEKECVREKLNLLHEFLQTEIKSQLCDLETKLHKEELSEEGYLAKVKSLLNKDLSLEN--GTHTLTQKANGCPANGSRP---TWRAEMADSNR----SPRSRPKPRGPRRSKSDSDTLSVETSPSSVATRRTTRQTTITAHFTKGPTKRKPKEESEEGNSAESAAEE-RDQDKKRRVVDTESGAAAA---VEKLEEVTAGTQLGPEEPCEQEDDNRSLRRHTRELSLRRKSKEDPDREARPETHLDEDEDGKKDKRSSRPRSQPRDPAAKRRPKEAEPEQVAPETPEDRDEDEREEKRRKTTRKKLESHTVPVQSRSERKAAQSKS-VIPKINSPKCPECGQHLDDPNLKYQQ-HPEDAVDEPQMLTSEKLSIYDSTSTWFDTYEDSPMHRFTSFSVYCSRGHLCPVDTGLIEKNVELYFSGCAKAIHDENPSMEGGINGKNLGPINQWWLSGFDGGEKVLIGFSTAFAEYILMEPSKEYEPIFGLMQEKIYISKIVVEFLQNNPDAVYEDLINKIETTVPPSTINVNRFTEDSLLRHAQFVVSQVESYDEAKDDDETPIFLSPCMRALIHLAGVSLGQR------RATRR-VMGATKEK--DKAPTKATTTKLVYQIFDTFFSEQIEKYDKEDKENAMKRRRCGVCEVCQQPECGKCKACKDMVKFGGTGRSKQACLKRRCPNLAVKEADDDEEADD-DVSEMPSPKKLHQGKKKKQNKDRISWLGQPMKIEENRTYYQKVSIDEEMLEVGDCVSVIPDDSSKPLYLARVTALWEDKNGQMMFHAHWFCAGTDTVLGATSDPLELFLVGECENMQLSYIHSKVKVIYKAPSENWAMEGGTDPETTLPGAEDGKTYFFQLWYNQEYARFESPPKTQPTEDNKHKFCLSCIRLAELRQKEMPKVLEQIEEVDG--RVYCSSITKNGVVYRLGDSVYLPPEAFTFNIKVASPVKRP-KKDPVNETLYP-EHYRKYSDYIKGSNLDAPEPYRIGRIKEIHCGKKKG-KVNEADIKLRLYKFYRPENTHRSYNGSYHTDINMLYWSDEEAVVNFSDVQGRCTVEYGEDLLESIQDYSQGGPDRFYFLEAYNSKTKNFEDPPNHARSPGNKGKGKGKGKGKGKHQVS--EPKEPE-AAIKLPKLRTLDVFSGCGGLSEGFHQAGISETLWAIEMWDPAAQAFRLNNPGTTVFTEDCNVLLKLVMAGEVTNSLGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSYRRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEIQNGASNSEIPYNGEPLSWFQRQLRGSHYQPILRDHICKDMSPLVAARMRHIPLFPGSDWRDLPNIQVRLGDGVIAHKLQYTFHDVKNGYSSTGALRGVCSCAEG-KACDPESRQFSTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDSYRFFGNILDRHRQVGNAVPPPLAKAIGLEIKLCLLSSARESASAAVKAKEEAATKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26358-1", "uniprot_id": "DNMT1_HUMAN", "id": "P26358-1", "name": "DNA (cytosine-5)-methyltransferase 1", "aln": "MPARTAPARVPTLAVPAISLPDDVRRRLKDLER--DSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLEN--GAHAYNREVNGRLENGNQARSEARRVGMADANS----PPKPLSKPRTPRRSKSDGEAK-PEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARP-LPAEEPERAKSGTRTEKEEERDEKEEKR-LRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGD-EKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEP----------TEKKMARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQ-HPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRR----AQARRQTIRHSTREK--DRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDD-NIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGD-DGKTYFYQLWYDQDYARFESPPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDS--RVLYYSATKNGILYRVGDGVYLPPEAFTFNIKLSSPVKRP-RKEPVDEDLYP-EHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEYGEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQAC--EPSEPE-IEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESASAKIK--EEEAAKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YUX4-1", "uniprot_id": "A0A8M6YUX4_DANRE", "id": "A0A8M6YUX4-1", "name": "DNA (cytosine-5)-methyltransferase", "aln": "MPTKTS-----------LSLPEDVKERLQVLDEGGDSLSDEECVKEKLRLLQEFLLADTQDQLKNLEDKLKSSELSTEVYMSEVKAVLKKALGVVKEGDGVEQNGHSNGFSENGSHKDNGEQEGAMDTQEEGDAIKSPSAPKGRGGRRSKADSEPK--KSPASSRVTRNTGKQQTIVSMFSRVPKRKSDELNGEPANGDTEIKTE-----------------------------------------------------------------------------------------------------------------------ETITEEVREEKRLKTEDEKPE----------AENAANLKPVSTAKTPPPKCPDCRQYLDDSDLKFFQGDPDDALDEPEMLTDERLSLFDSNEDGFESYEDLPQHKITNFSVYDKRGHLCPFDSGLIEKNVELYFSCAVKPIYDDNPCMDGGVPAKKLGPINAWWITGFDGGEKALIGFTTAFADYILMDPSEEYSAIFALMQEKIYMSKIVVEFLQKNQDATYEDLLNKIETTVPPAGLNFNRFTEDTLLRHAQFVVEQVESYDEAGDSDEQPIIITPCMRDLIKLAGVTLGKSRQLYWRAARRQAVRHPTKIEKDNKGPTKATTTKLVYLIFDTFFSDQIDQN---NKDGGVKRQRCGVCEVCQAPDCGKCSACKDMIKFGGSGRSKQACQKRRCPNLAVKEAEDDENMDEEDVLPVKDTKKMSQTKKKKQTKNKISWVGEPLKTEGKKEYYMKVRVENEVLEVGDCVSVSPDDPSHPLYLARITALWD--DGEKMFHAHWFCRGTDTVLGESSDPLELFLVDECEDMQLSFIHGKVNVFYKAPSENWYMEGGMDEDIKVIDD-DGESFFYQLHYEGECARFETPPKVTPSEDCKYKFCASCTRNKEREAESVPHAYEPLEDEESDSKVFYGLVNYKGEQYKVGDSVYLPPEAFNFVVKAASPVKRSHRKDDVDEDLYP-EYYRKSSDYIKGSNLDAPQPFRIGRIKEIFCNKRSNGKPDTSEIKLRLYKFYRPENTHKGPKGAYHSDINQLYWSDEEATVSMTEVLTRCRVEYAEDLVESVQDYSNKGPDRFYFLEAYNAKTKSFEDPPNHARSAVNKGKGKGKGKGKGKGKAAPQEPQDQEPQEPVVPKLRTLDVFSGCGGLSEGFHQAGISETHWAIEMWDPAAQAFRLNNPGTTVFTEDCNVLLKLVMSGEKTNSLGQKLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSYLSYCDYYRPKFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPRYPEPLHVFAPRACSLSVAVDEKKYVSNVTRGNGGIYRTITVRDTMSDLPEIRNGAAALEISYNGEPQSWFQRQIRGSQYQPILRDHICKDMSALVAARMRNIPLAPGSDWRDLPNFEVRLRDGTTTKKLRYTHPDKKNGRSGTGALRGVCSCSEG-KPCDPADRQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRFFGNVLDKHRQVGNAVPPPLSKAIGLEVKKCVLEKMRENATEPVKQEKMELSD-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*: ***:.*:.**: *:. *.*:::***:***.**:*** :: :.** :** **:..*** * *:::**::*:* * : : . . . ** **.: . * : . . .* * ****:*.:. :...*. **.: :* **.: * : * ::. : :.* .:. . * : *: :**** ** :: .: :. *. .* .*:* :* *:***.:**: * .* **:***:***.* **::*:.. *::*: * *::* **** .:*****.*:******:**:** .*.*::::*.::**: .*:***** **::*******.****:*:**:*:**:** ** .**.*******:*********.* *:.****:*********: :*.******:*********.******:* *.** **:::**** **:****:**: * *: : .:: : :.*********** ******::**:: :*:. .**:********* *:****.*****:****:******* :*****:*:***::**: *: :: : ..**: * *****.*::***:*:.:* : :: ** ** :: * ********* ***.*:******:****: .. ******** ******* :*********.***:****:**.**:*:*:.** ** **** * : : . **:::*:*: *. : ****:***. *:** *.*** ** * * . :.:*:. * :*: :. :* . :* *::**.********.* :* :**:**. ::: *:* * : *** ************:*:********.* *:.. : : ::**:*: *********:. .:**:*** ********.*.:. * ** ***.*** *.:* ** **:*********:*:*.**********. ************ * :.. **.: * :***************:*********:* ******:************:********:******:** *** **:****************************************:*********:************::************************************************** :************.***.**:**:***:** ..* :****:*********::***: **.*: .. . . . :. : . ..***:*** **********::*** **. :.**:**. * *** *.:********* *. *.*** ***.********************************************************************:**:***:**:************:******:* *:* . :*.*: :* : :. ", "identical_positions": 896, "similar_positions": 347, "identity": "54.11%" }, { "cls_id": "homologset.agr.RGD:620980", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZW61-1", "uniprot_id": "A0A8I5ZW61_RAT", "id": "A0A8I5ZW61-1", "name": "Angiopoietin-1 receptor", "aln": "------MLMTVMHHALSFFLGLVEGAMDLILINSLPLVSDAET-SLTCIASGWHP-HEPITIGRDFEALMNQHQDP-LEVTQDVTREWAKKVVWKREKASKINGAYFCEGRVRGQAIRIRTMKMRQQASFLPATLTMTVDRGDNVNISFKKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVHLPHAQPQ-DAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPDCNRPCTTCKNNGVCHEDTGECICPPGFMGRTCEKACEPHTFGRTCKERCSGSEGCKSYVFCLPDPYGCSCATGWRGLQCNEACPYGHYGPDCKLRCHCTNEEMCDRFQGCLCSQGWQGLQCEKEGRPRMTPQIEDLPDHIEVNSG-KFNPICKASGWPLPTSEEMTLVKPDGTVLQPNDFNHTDHFSVAIFTVNRILPPDSGVWVCSVNTVAGMVEKPFNISVKVLPEPLHAPNVIDTGHNFAIINISSEPYFGDGPIKSKKLFYKPVN--QAWKYIQVMNEIVTLNYLEPRTDYELCVQLVRPGEGGEGHPGPVRRFTTASIGLPPPRGLSLLPKSQTALNLTWQPIFTSSEDEFYVEVERWSQQTRSDQQNIKVPGNLTSVLLNNLLPREQYSVRARVNTKAQGEWSEELRAWTLSDILPPQPENIKITNITDYTALVSWTIVDGYSISSIIIRYKVQGKNED-QHIDVKIKNATITQ-YQLKGLEPETTYHVDIFAENNIGSSNPAFSQEIRTLP---APKDLGG-GKMLLIAILGSAGMTCITVLLAFLIMLQLKRANVQRRMAQAFQNVREEPAVQFNSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYIAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDETLPSVSVGLTDSTSCVPGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02858-1", "uniprot_id": "TIE2_MOUSE", "id": "Q02858-1", "name": "Angiopoietin-1 receptor", "aln": "---MDSLAGLVLCGVSLLLYGVVEGAMDLILINSLPLVSDAET-SLTCIASGWHP-HEPITIGRDFEALMNQHQDP-LEVTQDVTREWAKKVVWKREKASKINGAYFCEGRVRGQAIRIRTMKMRQQASFLPATLTMTVDRGDNVNISFKKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVHLPHAQPQ-DAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPDCSRPCTTCKNNGVCHEDTGECICPPGFMGRTCEKACEPHTFGRTCKERCSGPEGCKSYVFCLPDPYGCSCATGWRGLQCNEACPSGYYGPDCKLRCHCTNEEICDRFQGCLCSQGWQGLQCEKEGRPRMTPQIEDLPDHIEVNSG-KFNPICKASGWPLPTSEEMTLVKPDGTVLQPNDFNYTDRFSVAIFTVNRVLPPDSGVWVCSVNTVAGMVEKPFNISVKVLPEPLHAPNVIDTGHNFAIINISSEPYFGDGPIKSKKLFYKPVN--QAWKYIEVTNEIFTLNYLEPRTDYELCVQLARPGEGGEGHPGPVRRFTTASIGLPPPRGLSLLPKSQTALNLTWQPIFTNSEDEFYVEVERRSLQTTSDQQNIKVPGNLTSVLLSNLVPREQYTVRARVNTKAQGEWSEELRAWTLSDILPPQPENIKISNITDSTAMVSWTIVDGYSISSIIIRYKVQGKNED-QHIDVKIKNATVTQ-YQLKGLEPETTYHVDIFAENNIGSSNPAFSHELRTLPHSPASADLGG-GKMLLIAILGSAGMTCITVLLAFLIMLQLKRANVQRRMAQAFQN-REEPAVQFNSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYIAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSD----VWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02763-1", "uniprot_id": "TIE2_HUMAN", "id": "Q02763-1", "name": "Angiopoietin-1 receptor", "aln": "---MDSLASLVLCGVSLLLSGTVEGAMDLILINSLPLVSDAET-SLTCIASGWRP-HEPITIGRDFEALMNQHQDP-LEVTQDVTREWAKKVVWKREKASKINGAYFCEGRVRGEAIRIRTMKMRQQASFLPATLTMTVDKGDNVNISFKKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVHLPHAQPQ-DAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPECNHLCTACMNNGVCHEDTGECICPPGFMGRTCEKACELHTFGRTCKERCSGQEGCKSYVFCLPDPYGCSCATGWKGLQCNEACHPGFYGPDCKLRCSCNNGEMCDRFQGCLCSPGWQGLQCEREGIQRMTPKIVDLPDHIEVNSG-KFNPICKASGWPLPTNEEMTLVKPDGTVLHPKDFNHTDHFSVAIFTIHRILPPDSGVWVCSVNTVAGMVEKPFNISVKVLPKPLNAPNVIDTGHNFAVINISSEPYFGDGPIKSKKLLYKPVNHYEAWQHIQVTNEIVTLNYLEPRTEYELCVQLVRRGEGGEGHPGPVRRFTTASIGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQK-SDQQNIKVPGNLTSVLLNNLHPREQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITHSSAVISWTILDGYSISSITIRYKVQGKNED-QHVDVKIKNATITQ-YQLKGLEPETAYQVDIFAENNIGSSNPAFSHELVTLPESQAPADLGG-GKMLLIAILGSAGMTCLTVLLAFLIILQLKRANVQRRMAQAFQNVREEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSD----VWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O73791-1", "uniprot_id": "TIE2_DANRE", "id": "O73791-1", "name": "Angiopoietin-1 receptor", "aln": "MCLLDSCTALLLLG--CWMSGSAVRISDVTLVNPDPVVSPLTAPSLLCVSSDWSSGGSVLALGQEFPRPQGSVLALGQEFPHTEPRPHPAAATVTWSSRSHAFGAFYCQIRN-STGRKIYTYKMLQEAAFLPESLTITVNQGENINISYSRRLYSPEDTVIHKNGHFEHSSPKEDISDIIHYPVTNAKAESHAGIYAIRYISAAPSSAAITRLIVRSCRAGFWGPNCTESCPRCANGGVCDDTTGECVCPPGFRGHTCDIVCGEGRFGAGCKERCVDG-VCRALVFCLRDPYGCSCASGWRGLSCNDACPDGYYGAGCTQKCVCAKG-RCDRFRGCVCAG-RHGSRCEEADS---SPVISHLRD-VEINTGVELSVNCSASGRPAPLHGDITLITANRTTIAAVDTHTLNDQSTSVFRVQQVRVSSAGRWRCQVNNTHMQVEDEFTVEVKVPPRPQNPPVLQGSGPRHLLLLLNTEPYSGDGPIATTTLLYRPAS-AHTWSSVTAHGPLVRLDNLYPMTQYLTQVQLSRPGPGGAGQAGPAATFSTQVLELP--VGVKLSAVSQTALLLSWD--IAPAEQHCTYEVSCLQAGAPGTLRTFQLPSNSSAMHLSDLKPRHKYQCTVRS-SCGVGQNHPSASAWTLSDQLPPPPANISIWNISDTSAVLTWAVAEGESVSRAVIRFQQVEQAQYRQQVELPVQTQQLHMRFQLLGLRPNTGYQLQLWTVNNMGESAESPPVSLMTLPQQESSALFAAHGHLLLYAILGSAGMTCCTVLLAFCIVLQLKRNTLQRRIHS---ILREEPAVHFSS-APPPHRRSAVVSRSLVFPALQWSDIQFQDVLGEGNFGQVLKARIRKDGLRMDAAVKRMKDYASQDDHRDFAGELEVLCRLGPHKNIIHLLGACEHRGYLYLAIEFAPHGNLLDFLRKSRVLETDPAFAIAHRTASTLSSQQLLAFSADVARGMSYLSQKQFIHRDLAARNVLVGENFVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSD----VWSYGVLLWEVVSLGGTPYCGMTCAELYEKLPLGFRLEKPLNCDDEVYELMQQCWREKPFERPSFSQILLSLGRMLEERKTYVNTTLYEKFTYAGIDCSAEEAG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * . *: *:*. *:** : ** *::*.* . . :::*::* .. *..: .* . .. . .. *: **::*: * . . :* * ** *:*:*** :**:**::*:*:***:.: * . **:**:*** * ** *:.::.**:. :.:*:.: .**:*: ***.. ::*:****** *.* ***:*.. *. * *.***.: ****:***** *:**: .* ** ***** . *:: **** ********:**:**.**:** *.**..*. :* * : ****:**:*: :* :**. . :* * .* * :*:*:* ::. *.*** * * ::**:..: *.: . * : : *.::* :::: ..:* * *.**.. **. *.:.*** *.* :.* : .:* .. :: :.:*** ***** :..*:*:*.. .:*. : . . :. *: * * *:* *** * * ** *:.**. *:* : ** *:.* . ***:* *:*: :. :*:. **. . . :.:::*.* ::: *.:* **.:* .* : . *: . ****** *** * **.* **:. :*:::*:: :* *:* **:: : : *:::: ::. : :** **.*:* *:::::: **:*.* : . .: *** :. :.. *::** ********** ****** *:***** .:***: . ******:*.* : . :*: . . ::*.*:*.**:****:*************:*********:****:***:**************:** * ***:****************:*************************: *********** *:*******.****************:*****::******************************************* * *: ****************** *:*************:**:*******:*****:***:**.******************************.", "identical_positions": 560, "similar_positions": 296, "identity": "49.12%" }, { "cls_id": "homologset.agr.RGD:620981", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47728-1", "uniprot_id": "CALB2_RAT", "id": "P47728-1", "name": "Calretinin", "aln": "-------------------MAGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSK--SDNFGEKMK-EFMQKYDKNSDGKIEMAELAQILPTEENFLLCFRQH--VGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRPYD--EPKLQEYTQTILRMFDLNGDGKLGLSEMSRLLPVQENFLLK--FQG-MKLTSEEFNAIFTFYDKDGSGYIDENELDALLKDLYEKNKKE-MNIQQLTTYRKSVMS---LAEAGKLYRKDLEIVLCSEPPM------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08331-1", "uniprot_id": "CALB2_MOUSE", "id": "Q08331-1", "name": "Calretinin", "aln": "-------------------MAGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSK--SDNFGEKMK-EFMQKYDKNSDGKIEMAELAQILPTEENFLLCFRQH--VGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRPYD--EPKLQEYTQTILRMFDLNGDGKLGLSEMSRLLPVQENFLLK--FQG-MKLTSEEFNAIFTFYDKDGSGYIDENELDALLKDLYEKNKKE-MNIQQLTTYRKSVMS---LAEAGKLYRKDLEIVLCSEPPV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22676-1", "uniprot_id": "CALB2_HUMAN", "id": "P22676-1", "name": "Calretinin", "aln": "-------------------MAGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSK--SDNFGEKMK-EFMQKYDKNSDGKIEMAELAQILPTEENFLLCFRQH--VGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRPYD--EPKLQEYTQTILRMFDLNGDGKLGLSEMSRLLPVQENFLLK--FQG-MKLTSEEFNAIFTFYDKDRSGYIDEHELDALLKDLYEKNKKE-MNIQQLTNYRKSVMS---LAEAGKLYRKDLEIVLCSEPPM------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P41044-1", "uniprot_id": "CAB32_DROME", "id": "P41044-1", "name": "Calbindin-32", "aln": "MDSAAAAAAKRVQIEKAHNFMRQYRDPESRELKKLSANQFMDVWAHYDKDGNGYIEGTELDGFLREFVSSANATDISPEAVTDTMLEELKSCFMEAYDDNQDGKIDIRELAQLLPMEENFLLLFRFDNPLESSVEFMKIWREYDTDNSGYIEADELKNFLRDLLKEAKKINDVSEDKLIEYTDTMLQVFDANKDGRLQLSEMAKLLPVKENFLCRQVFKGATKLTKEDIEKVFSLYDRDNSGTIENEELKGFLKDLLELVKKDDYDAQDLAAFEETIMRGVGTDKHGKISRKELTMILLTLAKISPDDEE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::* .* :*:*.**:::* *:* ********.**:.*::*: .: :.:.: .: :*.: *::* **: **.*.****:: ****:** ****** ** . : **.***: **:****.******:***.** ****:*:: * * ** ***:*:*::** * **:* ****::****:**** : *:* ***.*::: :*::**:* ** *::.**..:**** * **: : *:*: :.:::* : **: **:* ::* : . : ", "identical_positions": 132, "similar_positions": 89, "identity": "42.58%" }, { "cls_id": "homologset.agr.RGD:620982", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJW1-1", "uniprot_id": "TSN2_RAT", "id": "Q9JJW1-1", "name": "Tetraspanin-2", "aln": "MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTIKDLSSEEKSPEYFYVGLYVLVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKDVAIRHVQSMYEEAYSDYVRDRGRGNGTLITFHSAFQCCGKESSEQVQPTCPKELPGHKNCIDKIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922J6-1", "uniprot_id": "TSN2_MOUSE", "id": "Q922J6-1", "name": "Tetraspanin-2", "aln": "MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTMKDLSSEDKSPEYFYVGLYVLVGAGALMMTVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKDVAIRHVQSMYEEAYSDYLKDRARGNGTLITFHSAFQCCGKESSEQVQPTCPKELPGHKNCIDKIETVISAKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60636-1", "uniprot_id": "TSN2_HUMAN", "id": "O60636-1", "name": "Tetraspanin-2", "aln": "MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYNDYLKDRGKGNGTLITFHSTFQCCGKESSEQVQPTCPKELLGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************************************::*:****:*********************:******************************************.*******:******.**::**.:**********:******************** *******:***:**.*************************************", "identical_positions": 204, "similar_positions": 16, "identity": "92.31%" }, { "cls_id": "homologset.agr.RGD:620983", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTY1-1", "uniprot_id": "E9PTY1_RAT", "id": "E9PTY1-1", "name": "", "aln": "MKRETFILGLLALLSYFTPGESHHFQPKPHPYQRLQQPIYHRRHSQVSSIYPRYGQYPRYFYVSQKQQAQKPQILPIQTPWQRVCPPGYTARLLHYHYSRFLCIPNKQLTSDKIETKVTTPAQTTKPTTDSTTPAPTTKPTTDSTTPAPTTKPTTDSTTPAPTTKPTTDSTTPAPTTKPTTDSTTPAPTNKPTTDSTTPAPTTKPTADSTTPAPTTKPTTDSTTPAPTT--------------KPTTDSTTPAPTTKPTTDSTTPAPTTKIPTT-PKPSTSTAIPTSTNSANSSSSTTTSSTTIQTTTLSPFQQMLQWLQMYFG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PYQ4-1", "uniprot_id": "E9PYQ4_MOUSE", "id": "E9PYQ4-1", "name": "", "aln": "MKNEMFILGLLALTSYFMPGESHHKS------RSSQFPVRKYLED------PRYPRYPRPHYSYG--FIPSSPKFPKDNQWYKMCPPGTTLMLISRRSPKFLCIPKRQIISDKTKPNATTPAPTTKPTTNATTPAPTNRTTTNAITPAPTPKPTTNATTPAPTNRTTTNATTPAPTLKPTTNATIPAPNNRTTTNATTPAPTTKPTTNTTTPAPTTKSTTNVTTPATTTNVTTPATTTNATTPATTTNATTPATTTNATTPATTTKSTTKEPTTSPKPSTSTAIPTTTKSANSTSSTTTS-TTIQTTAPTFAEVFWKFFQQIFRLKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99935-1", "uniprot_id": "PROL1_HUMAN", "id": "Q99935-1", "name": "Opiorphin prepropeptide", "aln": "-MKLTFFLGLLALISCFTPSESQRFS--------------------------------RRPYLPG--QLPPPPLYR--PRWVPPSPP----PPYDSRLNSPLSLP---FVPGRVPPSSFSRFSQAVILSQLFPLESIRQPRLFPGYPNLHFPLRPYYVGPIRILKP------PFPPIPFFLAIYLPISNPEPQINITTADTTITTNPPTTATATTSTSTKPTMTISSST--------------VPISSTPEPATSISAATPAASTENTTQILAN----------RPHTVLLNATVQVTTSNQTILSSP--AFKSFWQKLFAIFG---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:****** * * *.**:: . * * . * .** : *.:* : ..: .. : : :: . . :. . * . . * :. * *. * .. .. : **. .* .... :*:.*.*:..*. * :.:* . :.:. **.: ..:* :::. **: :. . * *:: ..*** ** ::. : : : : * ", "identical_positions": 46, "similar_positions": 82, "identity": "14.07%" }, { "cls_id": "homologset.agr.RGD:620984", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51886-1", "uniprot_id": "LUM_RAT", "id": "P51886-1", "name": "Lumican", "aln": "-MNVCTFTLV--LALVGSVSGQYYDYDAP-LFMYGELSPNCAPECNCPHSYPTAMYCDDLKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGKVFSKLKQLKKLHINYNNLTESVGPLPKSLQDLQLANNKISKLGS--FDGLVNLTFIYLQHNQLKEEAVSASLKGLKSLEYLDLSFNQMSKLPAGLPTSLLTLYLDNNKITNIPDEYFNRFTGLQYLRLSHNELADSGVPGNSFNISSLLELDLSYNKLKSIPTVNENLENYYLEVNKLEKFDVKSFCKILGPLSYSKIKHLRLDGNPLTQSSLPPDMYECLRVANEITVN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51885-1", "uniprot_id": "LUM_MOUSE", "id": "P51885-1", "name": "Lumican", "aln": "-MNVCAFSLA--LALVGSVSGQYYDYDIP-LFMYGQISPNCAPECNCPHSYPTAMYCDDLKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGKVFSKLKQLKKLHINYNNLTESVGPLPKSLQDLQLTNNKISKLGS--FDGLVNLTFIYLQHNQLKEDAVSASLKGLKSLEYLDLSFNQMSKLPAGLPTSLLTLYLDNNKISNIPDEYFKRFTGLQYLRLSHNELADSGVPGNSFNISSLLELDLSYNKLKSIPTVNENLENYYLEVNELEKFDVKSFCKILGPLSYSKIKHLRLDGNPLTQSSLPPDMYECLRVANEITVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51884-1", "uniprot_id": "LUM_HUMAN", "id": "P51884-1", "name": "Lumican", "aln": "-MSLSAFTLF--LALIGGTSGQYYDYDFP-LSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGS--FEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQQ7-1", "uniprot_id": "Q6IQQ7_DANRE", "id": "Q6IQQ7-1", "name": "Lumican", "aln": "MFALGSILLAGLLSLSLAQYDYYDEYYIPSAPLEGVSSPSCAQECECPINFPTAMYCNERNLKFIPIVPTGIKYLYLQNNFIEEIKAGVFDNATDLRWLVLDNNNITSDKIQAGTIDKLGSLEKLLFSHNKLTKPPGSLSKSLDELKLIGNKLTSFPANTLAGMENLTTVHLSKNKLTTESLTGAFKGLKSLILLDVSENKLKKLPSGVPASLLMLYADNNDIDSIPNGYLAKLPLLQYLRISHNKLVDSGVPAGVFNVSSLLELDLSFNKLKTIPEINESLEHLYLQVNEINKFELTNICRFSSPVNYSRLRTLRLDGNNITHSSMPDDTANCLRQASEIIFE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: * *:* . . * :* * : * **.** **:** .:*:****:: :** :*:**.*******:** *:.*. .*:*.***:**:**:* : ..**:. .:.** .*:** :.:*:**:. *.*.***::*:* **::.: : : *: *** ::*.:*:*. ::::.::****** **:* *:: :**:*:*.*** ** ***.* .**: *: :: *****:***:*.***:*.. **:***:*****:****.** :**.**: **:**:::**::..:*:: .*:.**::: ****** ::.:*:* * :*** *.*: .:", "identical_positions": 155, "similar_positions": 124, "identity": "45.06%" }, { "cls_id": "homologset.agr.RGD:620986", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K0T0-1", "uniprot_id": "RTN1_MOUSE", "id": "Q8K0T0-1", "name": "Reticulon-1", "aln": "MAAPPDLQDEPLSLGSPGSQWFGGRGDGEDEATAVMGARPAQQDGEPAWGSGAGAGVTSSRELCSGPARSPPVAMETASTGMAAVPDALDHSPSSTLKDGEGACYTSLISDVCYPPREDSAYFTGILQKENGHITTSESPEEPETPGPSLPEVPGMEPQGLLSSDSGIEMTPAESTEVNKILADPLDQMKAEAYKYIDITRPQEAKGQEEQHPGLEDKDLD-FKDKDTEVSTKAEGVRAPNQPAPVEGKLIKDHLFEESTFAPYIDELSDEQHRVSLVTAPVKITLTEIEPPLMTATQETIPEKQDLCLKPSPDTVPTVTVSEPEDDSPGSVTPPSSGTEPSAAESQGKGSVSEDELIAAIKEAKGLSYETTESPRPVGQVADKPKTKTRSGLPTIPSPLDQEASSAESGDSEIELVSEDPMASEDALPSGYVSFGHVSGPPPSPASPSIQYSILREEREAELDSELIIESCDASSASEESPKREQDSPPMKPGALDAIREETGSRATEERAPSHQGPVEPDPMLSFAPAAALQSRPEPSSGDGASVPEPPRSQQQKPEEEAVSSSQSPTATEIPGPLGSGLMPPLPFFNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQLYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQVDQYLGLVRTHINTVVAKIQAKIPGAKRHAE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64548-1", "uniprot_id": "RTN1_RAT", "id": "Q64548-1", "name": "Reticulon-1", "aln": "MAAPPDLQDEPLSPANPGSQLFGGRGEGEE--ATPKGARPAQQDGEPAWGSGAGAGVVSSRGLCSGPARSPPVAMETASTGVAAVPDALDHSSSPTLKDGEGACYTSLISDICYPPREDSAYFTGILQKENGHITTSESPEELGTPGPSLPEVPGTEPHGLLSSDSGIEMTPAESTEVNKILADPLDQMKAEACKYIDITRPQEAKGQEEQSPGLEDKDLD-FKDKDSEVSTKPEGVHAPNQPSPVEGKLIKDNLFEESTFAPYIDELSDEQHRMSLVTAPVKITLTEIGPPVMTATHETIPEKQDLCLKPSPDTVPTVTVSEPEDDSPGSVTPPSSGTEPSAAESQGKGSVSEDELIAAIKEAKGLSYETTESPRPVGQAADRPKVKARSGLPTIPSSLDQEASSAESGDSEIELVSEDPMASEDALPSGYVSFGHVSGPPPSPASPSIQYSILREEREAELDSELIIESCDASSASEESPKREQDSPPMKPGVLDAIREETSSRATEERAPSHQGPVEPDPILSFTP-VTLQSRPEPSSGDGAPVPEPPKSQQQKPEEEAVSSSQSPAATEIPGPLGSDLVPPLPFFNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQLYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQVDQYLGLVRTHINTVVAKIQAKIPGAKRHAE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16799-1", "uniprot_id": "RTN1_HUMAN", "id": "Q16799-1", "name": "Reticulon-1", "aln": "MAAPGDPQDELLPLAGPGSQWLRHRGEGENEAVTPKGATPAPQAGEPSPGLGARAREAASREAGSGPARQSPVAMETASTGVAGVSSAMDHTFSTTSKDGEGSCYTSLISDICYPPQEDSTYFTGILQKENGHVTISESPEELGTPGPSLPDVPGIESRGLFSSDSGIEMTPAESTEVNKILADPLDQMKAEAYKYIDITRPEEVKHQEQHHPELEDKDLD-FKNKDTDISIKPEGVREPDKPAPVEGKIIKDHLLEESTFAPYIDDLSEEQRRAPQITTPVKITLTEIEPSVETTTQEKTPEKQDICLKPSPDTVPTVTVSEPEDDSPGSITPPSSGTEPSAAESQGKGSISEDELITAIKEAKGLSYETAENPRPVGQLADRPEVKARSGPPTIPSPLDHEASSAESGDSEIELVSEDPMAAEDALPSGYVSFGHVGGPPPSPASPSIQYSILREEREAELDSELIIESCDASSASEESPKREQDSPPMKPSALDAIREETGVRA-EERAPSRRGLAEPGSFLDYPS-TEPQPGPELPPGDGALEPETP-MLPRKPEEDS-SSNQSPAATKGPGPLGPGAPPPLLFLNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQFYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAKIQAKIPGAKRHAE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1JHT6-1", "uniprot_id": "E1JHT6_DROME", "id": "E1JHT6-1", "name": "Reticulon-like protein", "aln": "-----------------------------------------------------------------------------MDRNFDELKKEAAATNEDIFKQAQRAYEDSALG-------GDTGNVSGGAQDDNAHTEHYFANEQ--------------KKLDFGDAQEFVQRLAADAKDAKLDLDTKFAQKTDDFEDFLRDAGKEVKQGISGLTTDFMNAERG-FSAPLAPFSETVAQAPVIPAQAPAVPDHAPAVPAPVAPAPAVPAPLPVEEDLLGSFTDQPSAPLQAFQPTAPSTANFYDDEEDDFLGKPTTAAPAAPVAPLTKANQDSDTESPSVSYTPSPAKKP---------IVDALKDQDNEKFISSED------LASDFKEEPRSAPTPAPAPAPILDAAP--------AVAPAPVAVPVSVP--------VAKPQPVPVAVPVTTALITDLD----DEEVVFK-----PTVQEAPKAPTIAAPVVE-------------------------------------------PKPEPPKPKVEPAKPKVVPVAPVESTQPQPKIASVEEIFCKYGLDAWFKPERLHP-QVESLIYWRDVKKSGIVFGAGLITLAAISSFSVISVFAYLSLLTLFGTVAFRIYKSVTQAVQKTNEGHPFKDYLELDLTLSHEKVQNIAGVAVAHINGFISELRRLFLVEDIIDSIKFGVILWVFTYVGAWFNGMTLVILAFVSLFTLPKVYENNKQSIDTHLDLVRSKLTEITDKIRVAIPIGNKKPEAAAESEKDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12443-1", "uniprot_id": "RTN2_YEAST", "id": "Q12443-1", "name": "Reticulon-like protein 2", "aln": "-----------------------------------------------------------------------------MNRNTTTNKNANLNNSRNANAPGEAGHQN----------KTGLIYWTNPSKSGASFAATLV------------------SLLILRNVNVISVLLKIGYMVLFTSFAVELSTKVLFDKGVVSRFGMQESPDLVGVLKPHIDRELDRLPALEDRIRKLVFAHRTRNNFTIGVSLYFLHGLFAIFSMNTVLIMTTIFLYTVPLIYDRKQARIDRAIDRMKDLVIHRFHKNYNKVVEKTEPYIDKIIPPQTDEGSYSTSISNENKSSTSQRNKSG---------------------------------LSSSEFDNMNDTSASKSGKDSYSTSQYN-------------------------------RAEYPVSQNENIGTLKSGK-------------------QEIPTEKDFNN-----------------------------------------------RHENFSKPDVKTYDPRTVDIEEELAAHQRELEQNLKD-----------------------------------------------GDYNLVGSKEIPDPITVPAPTRHTTKPAESQSIPIKNNETLHKTTHGLKQKLQHA-------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . .: . . :. :. .. . : . : : : : : : : . : . : . . . . . : . :: : : : . .. .. . . . .* :. . : . . .. : :: *.: . : . :* *. . . . * : . .:.::. :: .. . : *:: .:: .* *. .*.: ", "identical_positions": 9, "similar_positions": 94, "identity": "1.14%" }, { "cls_id": "homologset.agr.RGD:620987", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54697-1", "uniprot_id": "NALDL_RAT", "id": "O54697-1", "name": "Aminopeptidase NAALADL1", "aln": "-------------------MHWAKILGVGIGAAALLGLGIILGHFAIPKATEPLASSVSDS-----------------------------QDLDLAILDSVMGQLDASRIRENLRELSKEPHVATSARDEALVQLLLGRWKDS-------------ASGLDTAKTYEY------------TVLLSFPSTEQPNSVEVVGP-NGTVFHSFQPFEKNLTGEQA--EPNVLQPYAAYAPPGTPKGPLVYANRGSEDDFKKLEAEGINLKGTIALTRYGSVGRGAKAINAARHGVVGVLVYTDPGDINDGKSLPNE---TFPNSWGLPPSGVERGSYYEYFGDPLTPYLPAHPV--SFRLDPHNISGFPPIPTQPIGFEDAKNLLCNLNGTSAPDSWQGALGCEYKLGPGFEPNGNFPAGSEVKVSVYNRLELRNSSNVLGIIQGAVE---PDRYVIYGNHRDSWVHG-AVDPSSGTAVLLEISRVLGTLLKKGTWRPRRSIIFASWGAEEFGLIGSTEFTEEFLSKLQERTVTYINVDISVFSNATLRAQGTPPVQSVIFSATKEISAPGSSGLSIYDNWIRYTNRSSPVYGLVPSMGTLGAGSDYASFIHFLGITSMDLAYTYDRSKTSARIYPTYHTAFDTFDYVEKFLDPGFSSHQAVARTAGSVLLRLSDSLFLPLNVSDYSETLQSFLQAAQENLGALLESHN--ISLGPLVTAVEKFKAAAAALNQH---------------ILTLQKSSPDPLQVRMVNDQLMLLERAFLNPRAFPEERYYSHVLWAPNTASVATFPGLANAYARAQEINSGAEAWAEVERQLSIAVMALEGAAATLQPVTDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7M758-1", "uniprot_id": "NALDL_MOUSE", "id": "Q7M758-1", "name": "Aminopeptidase NAALADL1", "aln": "-------------------MHWVKILGVALGAAALLGLGIILGHFAIPKATSPLTSSTSDS-----------------------------QDLDLAILDSVMGQLDASRIRENLRELSKEPHVATSPRDEALVQLLLGRWKDT-------------ATGLDSAKTYEY------------RVLLSFPNAEQPNSVEVVGP-NGTTFHSFQPFEKNLTGEQA--GPNVLQPYAAYAPPGTPKGLLVYANQGSEEDFKELETQGINLEGTIALTRYGGVGRGAKAINAAKHGVVGVLVYTDPGDINDGKSLPNE---TFPNSWRLPPSGVERGSYYEYFGDPLTPYLPAHPS--SFRLDPHNTSGFPPIPTQPIGFEDARDLLCNLTGTSAPAFWQGALGCEYKLGPGFEPNGSFPAGSEVKVSVHNRLELRTSSNVLGIIQGAVE---PDRYVIYGNHRDSWVHG-AVDPSSGTAVLLEISRVLGTLLKKGTWRPRRSIIFASWGAEEFGLIGSTEFTEEFLSKLQERTVAYINVDISVFSNATLRAQGTPPVQSVIFSATKEISAPGSSGLSIYDNWIRYTNRTSPVYGLVPSLGTLGAGSDYAAFVHFLGITSMDLAYTYDRSKTSARIYPTYHTAFDTFDYVEKFLDPGFSSHQAVARTAGSVLLRLSDSLFLPLNVSDYSETLQSFLQAAQEALGTQLEKQN--ISLGPLVTAVANFKAAAASLGEH---------------ILTLQKSSPDPLQVRMVNDQLMLLERAFLNPRAFPEERHYSHVLWAPNTASVDTFPGLANAYAKAQEINSGSEAWAEVQRQLSIVVTALEGAAATLVPVADL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQQ1-1", "uniprot_id": "NALDL_HUMAN", "id": "Q9UQQ1-1", "name": "Aminopeptidase NAALADL1", "aln": "-------------------MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLAP----------------------------------QDLDLEILETVMGQLDAHRIRENLRELSREPHLASSPRDEDLVQLLLQRWKDP-------------ESGLDSAEASTY------------EVLLSFPSQEQPNVVDIVGP-TGGIIHSCHRTEENVTGEQG--GPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQGIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDE---TFPNSWYLPPSGVERGSYYEYFGDPLTPYLPAVPS--SFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNGTLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVE---PDRYVLYGNHRDSWVHG-AVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGLIGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPGDLSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTSARIYPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSFLQAAQQDLGALLEQHS--ISLGPLVTAVEKFEAEAAALGQR---------------ISTLQKGSPDPLQVRMLNDQLMLLERTFLNPRAFPEERYYSHVLWAPRTGSVVTFPGLSNACSRARDTASGSEAWAEVQRQLSIVVTALEGAAATLRPVADL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47161-1", "uniprot_id": "VPS70_YEAST", "id": "P47161-1", "name": "Vacuolar protein sorting-associated protein 70", "aln": "MRMIQRERKREKEEGQLKERTVVNMADPDDNEAEATGLQQYSGETTRDDNEESMNDSFTLTSRNRGRSNTISSIVSGYEIMKEHMDKEKFMYLILASLLLYMGFVAAFAPRTSLSRDFRRFHSSRLTNAEVYRIYLNSLQQENRAKEHVYKYAGYMSNGASDSSTFKYTLDEFLDMGYKPKVEKYYPWIGEPVDTNVAPLENGKVVYEASMIEDRVKGDPASHARKRQKGFHQYSKNGSVTARYVFCNYGSISDYKLLLKKNIDIEDKIHIVRSGKILPGLKVKNAELYGASSVIIYTDP--FDDGKVTEENGFLHYPYGPARNPSYIRRDSVNYFSDTPGDPTTPGYPSKDSDTEHMSPVGRVPRIPSVPMSARDVQPILERLNGR----------GFQIGPGSNIKDFGSFTGPSSSIDKVHLHNELTYNIKEMSSVEVSIPGIFTEGEIIIGAHRDSLASSSAGDANSGSAILLEIARGMSKLLKHG-WKPLRPIKLISWDGERSGLLGSTDYAEAHAAILRRRALVYLNLDNAISG-TNFHCKANPLLQDVIYEAAKLTEFNGHEDWSLFDHWKYTSN---------ATISLLDGLSSYTSFQYHLGVPAAHFQFNAN--DTSGAVYHS-NSVFDSPTWLEKFTNSDYKLHNTMAMFVGLTTLMLSENELARFNTHVYLKKIYNWYIAWHSNLSSAFPQDDEVNSLAKRVLDLLKVATQEDSIQFDQQNGILYKECREALPVWAFYKKIKSYIKLQRSNSKSKQIDQLFITHRGLKDREWMKYSLLAP-----SKFEGSVGEVLPGLHEGLADIDRNEVIQWLTILLSQFSNVRYLLQ-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: . . * ** *. : . ..: * * * ** : * * .* . :. * : .. * * :: .* . :.: * * :* :* .::. .* .:. *..:.*: . . : : *: *: . *:.* *: .*:* * :.*.::..* :.* * : * *. ** :*. .*::**** ::** :: :* . ** :.*.* : . * * *. * * . . .* **: *:. .*.: :* .*.* * . *..:. *.*.. *. .*: : ** . : :. :. :: .: :: * **** . . * *..**:*:***::* :..***:* *:* *.* : **..*. **:***:::* . *:.*::.*:*:* :: . :.:: :..* :*.*::.*:* * . *::*:* * .::. *.. *.*:.* :.**:.: .: :. : .**. :* : ::.**: :::** :..:. *:::* .* . * **:. : ::. * :.: .: * :. *.: : ... **. * : :. : :: : :: * . :::: *.: ::: *:. *.: :.. .: * ** .* * . . . . ** : *:* : :... * ", "identical_positions": 158, "similar_positions": 267, "identity": "18.65%" }, { "cls_id": "homologset.agr.RGD:620988", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6RJR6-1", "uniprot_id": "RTN3_RAT", "id": "Q6RJR6-1", "name": "Reticulon-3", "aln": "----MAESSAATQSPSVSSSSSGAEPSTLGGGGGSPGACPALGAKSCGSSCA-------------------VGLSSLCSDEPPS-----------KIMTSSFLSSSEIYNPDPTTPLG--SETLGSHLVAKD-GKDPLVLLD-----KKTLDSPQGTNKDRVDTPVSLAADIPCSHPSIPDS-------------FPEQPTFLSKETDPTEEWVVKNQEPKNPSEVPSGEDR-------SALDLGQ--------------RKAEHICTHSLSPSEP-AVASVEKDSPESPFEVIIDKATFDREFKDLYKESTDDLGGWAAHGDRESPADLLEMNDKVFPLRNKEAGRYPSSALLGRQFSHTTAALEEVSRCVNDMHNFTNEILTWDLDPQAKQQADKSP-CTTESTGLDRSEHRSEIPVINLKTSPQQKMPVCSFNG------------STPITRSTGDWTETFTE------GKPVKGYLSSTKEAGGKGVPDSSQP-----------------ISGSGAATVEVTLPDLRG-------------------------------------TWPNSVLGEVTEVDSSGESDDTVIEDTTENPSVKNNKVLPEKSDSLPSAAVKTSERENKETTSHETVR------SEMYENSEQQQAHAETPTQRSLEGQMSPQVPNM------LNEVIPENLAMTDTTRVCSAAPPSVLSETG-------FSLTVPASAKSESLLGKNVEDTDGSSPEDLMAALTGTEEKGTVD-KEKGDVLEAVLEKIANVKNTLPVELLHENKLSSSETKNTKSKYSEHSRETNG----------GAPKVSSDLEQEQLTIRAIKELG---AKQVQ----AERMSPGGKLKR--TFDPQSGPQNSSDILEHTDITTGSDLGIPKKPTIIKD-TRIDSISSLTKTETVNKHVLARLLSDFPVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHSYMNAAMVHVNKALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLVFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES97-1", "uniprot_id": "RTN3_MOUSE", "id": "Q9ES97-1", "name": "Reticulon-3", "aln": "----MAESSAATQSPSVSSSSSGAEPSALGGGGGSPGACPALGAKSCGSSCADSFVSSSSSQPVSIFSTSQAGLSSLCSDEPPS-----------KSMTSSFLSSSEIHNPDPTTPLGEKSETLGSQFVLAK-GKDPLVLLD-----KKKLDSPQGTNKDRVDAPVSLATGIPCSHPSIPDS-------------FPEQPAFLSKEIGPAEEWVVKDQEPKNPNKVPDGEDR-------SALDFGQ--------------SKAEHICTYSLSPSEL-PVASVEKDSPESPFEVIIDKATFDREFKDLYKENPNDLGGWAAHGDRESPADLLEMNDKLFPLRNKEAGRYPSSVLLGRQFSHTTAALEEVSRCVNDMHNFTNEILTWDLDPQAKQQANKTS-CTTESTGLDRSELRSEIPVINLKTNPQQKMPVCSFNG------------STPITKSTGDWTEAFTE------GKPVRDYLSSTKEAGGNGVPGSSQLHSELPGSMPEKW-----VSGSGAATVEVTLPNLRG-------------------------------------AWPNSVMGEVTEVDSSGESDDTVIEDITEKP------------DSLPSAAAKTSEREIKETPSRETVR------SEMCENSEQPQAQPETPTQKSLEGEVASQVPNT------LNEVTPEKLDMTNNPKVCSAAPPSVLNETG-------FSLTVPASAKLESLLGKYVEDTDGSSPEDLMAVLTGAEEKGIVD-KEEGDVLEAVLEKIADFKNTLPVELLHESELSGSETKNIKSKYSEDSRETTG----------GAPTMSPDLEQEQLTIRAIKELGERQAEKVQ----DEGISSGGKLKQ--TFAPQSGPQSSSDILEHTDVKTGSDLGIPKNPTIIKN-TRIDSISSLTKTEMVNKNVLARLLSDFPVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHVNKALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLVFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95197-1", "uniprot_id": "RTN3_HUMAN", "id": "O95197-1", "name": "Reticulon-3", "aln": "----MAEPSAATQSHSISSSSFGAEPSAPGGGG-SPGACPALGTKSCSSSCADSFVSSSSSQPVSLFSTSQEGLSSLCSDEPSS-----------EIMTSSFLSSSEIHNTGLTILHGEKSHVLGSQPILAKEGKDHLDLLD-----MKKMEKPQGTSNNVSDSSVSLAAGVHCDRPSIPAS-------------FPEHPAFLSKKIGQVEEQIDK--ETKNPNGVSSREAK-------TALDADDRFTLLTAQKPPTEYSKVEGIYTYSLSPSKVSGDDVIEKDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVHTDKESSEDISETNDKLFPLRNKEAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNEILTWDLVPQVKQQTDKSSDCITKTTGLDMSEYNSEIPVVNLKTSTHQKTPVCSIDG------------STPITKSTGDWAEASLQQENAITGKPVPDSLNSTKEFSIKGVQGNMQKQDDTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLK---------------------------------DEMDWQSSALGEITEADSSGESDDTVIEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIKEIPSCEREEKTSKNFEELVSDSELHQDQPDILGRSPASEAACSKVPDTNVSLEDVSEVAPEKPITTENPKLPSTVSPNVFNETE-------FSLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTETRDKGIVD-SER-NAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSKYSEQSKETNGSEPLGVFPTQGTPVASLDLEQEQLTIKALKELGERQVEKSTSAQRDAELPSEEVLKQTFTFAPESWPQRSYDILER-NVKNGSDLGISQKPITIRETTRVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PNQ3-1", "uniprot_id": "A0A8M9PNQ3_DANRE", "id": "A0A8M9PNQ3-1", "name": "Reticulon", "aln": "MADPMTQSSQISSSQGLNDGHSAASKDSKFSDSFFSSPVSLIQSPQDKRVVLGSDKPSENVATSLRFSSQSSSFSPVVYGTESSGSSGDNVDRTFKEKRELFDSPFSTQNQESPVKTSPVSERIKALEALAAKQNDFDRHDGGFPHFKERHYEKSPTESHGISSRLSFQKRTASNEQESPESPFEVLGEARRGSDFEDTADWMRAHLPPAPDFNTEEPDLDEGNECPMVQESPSKVIKPNNIETTEIPEPFAGVPDQFMDSPIKMADDNNQSKHDEDKQMKQGSVEEDSEFDLNFLPTAYMWEKQEKAETGDQGYQGFPDNKELPSSPAPPADCGSPSPIMSQQIEPSPTQHSNISKGSLEPAEIQEVDSSGESDDTVIEEAVSLPTLGNNDLDTKTPK---DEETIPNNEKQSIQVPIINVIETEEQVLSDDDEDQQLDVEQDIKDNENRQIVQEEGKGAPEQDHSEVEQVKTVETEERKPDYEISSQKSNTDTEVDHSPGHEAIEEDYESGIYLQSSPDSGGLNLEDSQEQSFMSQNLVSFEPLKESFLDKELDKTSEILFDLPPDISSPSNEPSDVETYLDHYASEELALKDQLNSSCFKENKVEKTELPKSVCLPDNKNICTLAQESFENVTDDINETLNEFRLDYESVPEPFLTDPSSDYPDDIETILPQNKMPSFDSEDLKSEIKTSTLQEQELPVQSTDQLPPVQENPPAPFPSFHNEQSSKISEVITVSVANKDAELPVITKSEPQVMTPKDLLDRPDSPDAMSDTETLEAECSVTAATDSFVEFMRECLKSRQDEEPETLSPGHKTIDQISKSAENQSSPAMIMDLEQERLTISALKELGSSQEEEDE-----NIITMKTVPKLEKAPLPTPNPASS-------VTSSSHTLPNEYQPDSLLPKEVEAIDIWVAEAYHLAEHVLTAILTHLTVNDLVHWRDPKKSGVVFGVSLLLLLSLAAFSVISVVSYLLLSLLCVTISFRIYKSVIQAVQKSNEGHPFKALMDKDVTVPPETFRKHVDGCLSHVNRALKQMSRLFLVEDLVDSLKLAVVMWLLTYVGAVFNGITILILADILLFSVPPIYEKNKTQIDHYIDIARTQFNTTVAKLQEKLPGAMKRCKAE-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JHT6-1", "uniprot_id": "E1JHT6_DROME", "id": "E1JHT6-1", "name": "Reticulon-like protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MDRNFDELKKEAAATNEDIFKQAQRAYEDSALGGD---------------------------------------TGNVSGGAQDD----------------------------------NAHTEHYFANEQKKLDFGDAQEFVQRLAADAKDAKLDLDTKFAQKTDDFEDFLRDAGKEVKQGISGLTTDFMNAERGFSAPLAPFSETVAQAPVIPAQAPAVPDHAPAVPAPVAPAPAVPAPLP------------VEEDLLGSFTDQPSAPLQAFQPTAPSTANFYDDEE---------------------DDFLGKPTT------------------------------------------------------------------------------------------------------AAPAAPVAPLTKANQDSDTESPSVS-------------------YTPSPAKKPIVDALKDQDNEKFIS---------------------------------------------SEDLASDFKEEPRSAPTPAPAPAPILDAAP-----------AVAPAPVAVPVSVPVAKPQP------VPVAVPVTTALITDLDDEEVVFKPTVQEAPKAPTIAAPVVEPKPEPPKPKVEPAKPK--------------------VVPVAPVESTQPQPKIASVEEIFCK-----------------------------------------------YGLDAWFKPERLHP----------------------------QVESLIYWRDVKKSGIVFGAGLITLAAISSFSVISVFAYLSLLTLFGTVAFRIYKSVTQAVQKTNEGHPFKDYLELDLTLSHEKVQNIAGVAVAHINGFISELRRLFLVEDIIDSIKFGVILWVFTYVGAWFNGMTLVILAFVSLFTLPKVYENNKQSIDTHLDLVRSKLTEITDKIRVAIPIGNKKPEAAAESEKDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04947-1", "uniprot_id": "RTN1_YEAST", "id": "Q04947-1", "name": "Reticulon-like protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSASAQHSQAQQQQQQKSCNCDLLLWRNP----------VQTGKYFGGSLLALLILKKVNLITFFLKVAYTILFTTGSIEFVSKLFLGQGLITKYGPKECPNIAGFIK-------------------------------------PHIDEALKQLPVFQAHIR-------------------------------------------------------------------------------------------------KTVFAQVPKHTFKTAVALFLLHKFFSWFSIWTIVFVADIFTFTLPVIYHSYKHEIDATVAQG--------VEISKQKTQEFSQMACEKTKPYLDKVESKLGPISNLVKSKTAPVSSTAGPQTASTSKLAADVPLEPESKAYTSSAQVMPEVPQHEPSTTQEFNVDELSNELKKSTKNLQNELEKNNA--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . : : . : . . * * :. . :. : *:: . . :: :: **: ::. : : .: :: ** :*. :: . . * : ::: . : : : . : .. : .. .:.: : : : * : . . : : . * : :: ", "identical_positions": 11, "similar_positions": 71, "identity": "0.97%" }, { "cls_id": "homologset.agr.RGD:620989", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JK11-1", "uniprot_id": "RTN4_RAT", "id": "Q9JK11-1", "name": "Reticulon-4", "aln": "MEDIDQSSLVSSSTDSPPRPPPAFKYQFVTEPEDEEDEEEEEDEEEDDEDLEELEVLERKPAAGLSAAAVPPA--AAAPLLDFSSDSVPPAPRGPLPAAPPAAPERQPSWERSPAAP---APSLPPAAAVLPSKLPEDDEPPARPPPPPPAGASPLAEP---------AAPPSTPAAPKRRGS-GSVDETLFALPAASEPVIPSSAEKIMDLMEQPGNTVSSGQEDFPSVLLETAASLPSLSPLSTVSFKEHGYLGNLSAVSSSEGTIEETLNEASKELPERATNPFVNRDLAEFSELEYSEMGSSFKGSPKGESAILVENTKEEVIVRSKDKED-LVCSAALHSPQESP-----VGKEDRVVSPEKTMDIFNEMQMSVVAPVREEYADFKPFEQAWEVKDTYEGSRDVLAAR----ANVESKVDRKCLEDSLEQKSLGKDSEGRNEDASFPSTPEPVKDSSRAYITCASFT-SATESTTANTFPLLEDHTSENKTDEKKIEERKAQIITEK-TSPKTSNPFLVAVQDSEADYVTTDTLSKVTEAAVSNMPEGLTPDLVQEACESELNEATGTKIAYETKVDLVQTSEAIQESLYPTAQLCPSFEEAEATPSPVLPDIVMEAPLNSLLPSAGASVVQPSVSPLEAPPPVSYDSIKLEPENPPPYEEAMNVALKAL-GTKEGIKEPESFNAAVQETEAPYISIACDLIKETKLSTEPSPDFSNYSEIAKFEKSVPEHAELVEDSSPESEPVDLFSDDSIPEVPQTQEEAVMLMKESLTEVS-ETVAQHK-EERLSASPQELGKPYLESFQPNLHSTKDAAS-NDIPTLTKKEKISLQMEEFNTAIYSNDDLLSSKEDKIKESETFSDSSPIEIIDEFPTFVSAKDDSPK-LAKEYTDLEVSDKSEIANIQSGADSLPCLELPCDLSFKNIYPKDEVHVS--DEFSENRSSVSKASISPSNVSALEPQTEMGSIVKSKSLTKEAEKKLPSDTEKEDRSLSAVLSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLT-VFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELR-RLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKDAMAKIQAKIPGLKRKAD---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99P72-2", "uniprot_id": "RTN4_MOUSE", "id": "Q99P72-2", "name": "Reticulon-4", "aln": "MEDIDQSSLVSSSADSPPRPPPAFKYQFVTEPEDEEDEEDEE-EEEDDEDLEELEVLERKPAAGLSAAPVPP---AAAPLLDFSSDSVPPAPRGPLPAAPPTAPERQPSWERSPAAS---APSLPPAAAVLPSKLPEDDEPPAR--PPAPAGASPLAEP---------AAPPSTPAAPKRRGS-GSVDETLFALPAASEPVIPSSAEKIMDLKEQPGNTVSSGQEDFPSVLFETAASLPSLSPLSTVSFKEHGYLGNLSAVASTEGTIEETLNEASRELPERATNPFVNRESAEFSVLEYSEMGSSFNGSPKGESAMLVENTKEEVIVRSKDKED-LVCSAALHNPQESPATLTKVVKEDGVMSPEKTMDIFNEMKMSVVAPVREEYADFKPFEQAWEVKDTYEGSRDVLAAR----ANMESKVDKKCFEDSLEQKGHGKDSESRNENASFPRTPELVKDGSRAYITCDSFS-SATESTAANIFPVLEDHTSENKTDEKKIEERKAQIITEK-TSPKTSNPFLVAIHDSEADYVTTDNLSKVTEAVVATMPEGLTPDLVQEACESELNEATGTKIAYETKVDLVQTSEAIQESIYPTAQLCPSFEEAEATPSPVLPDIVMEAPLNSLLPSTGASVAQPSASPLEVPSPVSYDGIKLEPENPPPYEEAMSVALKTS-DSKEEIKEPESFNAAAQEAEAPYISIACDLIKETKLSTEPSPEFSNYSEIAKFEKSVPDHCELVDDSSPESEPVDLFSDDSIPEVPQTQEEAVMLMKESLTEVS-ETVTQHKHKERLSASPQEVGKPYLESFQPNLHITKDAAS-NEIPTLTKKETISLQMEEFNTAIYSNDDLLSSKEDKMKESETFSDSSPIEIIDEFPTFVSAKDDSP----KEYTDLEVSNKSEIANVQSGANSLPCSELPCDLSFKNTYPKDEAHVS--DEFSKSRSSVSKVPLLLPNVSALESQIEMGNIVKPKVLTKEAEEKLPSDTEKEDRSLTAVLSAELNKTSVVDLLYWRDIKKTGVVFGASLFLLLSLT-VFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELR-RLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQAQIDHYLGLANKSVKDAMAKIQAKIPGLKRKAE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQC3-1", "uniprot_id": "RTN4_HUMAN", "id": "Q9NQC3-1", "name": "Reticulon-4", "aln": "MEDLDQSPLVSSS-DSPPRPQPAFKYQFVREPEDEEEEEEEE-EEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAEN-MDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDS-DMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASS-VNYESIKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLT-VFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELR-RLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E1JHT6-1", "uniprot_id": "E1JHT6_DROME", "id": "E1JHT6-1", "name": "Reticulon-like protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRNFDELKKEAAATNEDIFKQAQRAYEDSALGGDTGNVSGG-------AQDDNAHTEHYFANEQKKLDFGDAQEFVQRLAADAKDAKLDLDTKFAQKTDD---------------FEDFLRDAGKEVKQGISGLTTDFMNAERG--------------FSAPLAPFSETVAQAPVIPAQAPAVPDHAPAVPAPVAPAPAVPAPLPVEEDLLGSFTDQPSAP------------------------------------------------------------------------------------LQAFQPTAPSTANFYDDEEDDFLGKPTTAAPAAPVAPLT--------------------------------------------KANQDSDTESPSVSYTPSPAKKPIVDALKDQDNEKFISSEDLASDFKEEPR-SAPTPAPAPAPILDAAPAVAPAPVAVP-------VSVPVAKPQPVPVAVPVTTALITDLDDEEVVFKPTVQEAPKAPTIAAPVVEPKPEPPKPKVEPAKPKVVP--------VAPVESTQPQPKIASVEEIFCKYGLDAWFKPERLHPQVESLIYWRDVKKSGIVFGAGLITLAAIS-SFSVISVFAYLSLLTLFGTVAFRIYKSVTQAVQKTNEGHPFKDYLELDLTLSHEKVQNIAGVAVAHINGFISELR-RLFLVEDIIDSIKFGVILWVFTYVGAWFNGMTLVILAFVSLFTLPKVYENNKQSIDTHLDLVRSKLTEITDKIRVAIPIGNKKPEAAAESEKDK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04947-1", "uniprot_id": "RTN1_YEAST", "id": "Q04947-1", "name": "Reticulon-like protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSASAQHSQAQQQQQQKS----CNCDLLLWRN-------------PVQTGKYFGGSLLAL-------------LILKKVNLITFFLKVAYTILFTTGSIEFVSKLFLGQG-------------------------------------------LITKYGPKECPNIAGFIKPHIDEALKQLPVFQAHIRKTVFAQVPKHTFKTAVALFLLHKFFSWFSIWTIVFVADIFTFTLPVIYHSYK------------HEIDATVAQGVEISKQKTQEFSQMACEKTKPYLDKVESKLGPISNLVKSKTAPVSSTAGPQTASTSKLAADVPLEPESKAYTSSAQVMPEVPQHEPSTTQEFNVDELSNELKKSTKNLQNELEKNNA-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: ::: :: . .. ** : * . : : : . . :. : :: :. * : .: : . . :. : :: * . ...*: * : **: :: : : .: :: ** * : : : :*.: .*: : * : : :.::. :* :.:::.* . * . . ..: : : : * * . : . . .: : ::: :.: : ", "identical_positions": 20, "similar_positions": 96, "identity": "1.66%" }, { "cls_id": "homologset.agr.RGD:620990", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q794H2-1", "uniprot_id": "NP1L3_MOUSE", "id": "Q794H2-1", "name": "Nucleosome assembly protein 1-like 3", "aln": "-------MAEADPKMVTEPGAHGVAEEAMASTACDSGDESDSNSSSSTNSCSSSGSSSSGSSSSSSSSSSSSSSSSSSSSGSSGSSSNGSHLNRKKRVPEPSRRAQRRPSGKLFLDKLPQAVRNRVQALRNIQNECDKVDTLFLRAIHDLERKYAELNKPLYDKRFQIINAEYEP-TEEECEWNSE-EEFSGDEEMQDDTPNEMPPLEGEEEEESCNEKAEVKEEGTHVPEEVPEAKVEEEEAPKETPEVKTEEKDIPKEGAEEKAEEQESSKEIPEVKGEEKADSTDCIDIAPEEKEDVKEVTQANTENKDQP-TEEFTPRAPAREAQKRVPETRPEEGVNIKRARKGKPKKEDP-KGIPDYWLTVLKNVDKLGPMIQKCDEPILKFLSDVSLKFSNPGQPIGYTFEFHFLP--NPYFRNE--LLMKTYIIRSKPDHYDPFFAWGWEIEECKGCKIDWRR-GKDVTVTTTRSRPGITG--EIEVQPRVVPNASFFNFFSPPEIP-LIGKLE-PRE-DAILDEDFEIGQILHDNVILKSIYYFTGEIN-----------------------DPYYHDFRDYGNRKYYK------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q924R9-1", "uniprot_id": "NP1L3_RAT", "id": "Q924R9-1", "name": "Nucleosome assembly protein 1-like 3", "aln": "-------MAEADPKMVTEPAAQGVAEEAMASSACDSGDESDSNSSSSTTSCGSTGSSS--------SSSSSSSSSSSSSSGSSGSSSNGSHLHQKKRVPGPSRRAQRRPSGKLFMDKLPQAVRNRVQALRNIQNECDKVDTLFLRAIHDLERKYAELNKPLYDKRFQIINAEYEP-TEEECEWNSE-EEFSGDEEMQDDTPNEMPPLEGEEEEEIGKENTEVKEEVKDVPEEVPEAKVEEEEAPKETSEVKTEEKEIPKEGPEEKAEEQESSKEFPEVKVEEKTDSTDCIDIAPEEKEDLKDVTQANAEYTDQP-TEDSTPRAPVREAQKRVPETRPEERVNIKRARKGKPKKEDPPRGIPDYWLTVLKNVDKLGPMIQKCDEPILKFLSDVSLKFSNPGQPISYTFEFHFLP--NPYFRNE--LLMKTYIIRSKPDHYDPFFAWGWEIEECKGCKIDWRR-GKDVTVTT-RSRPAITG--EIEVQPRVVPNASFFNFFSPPEIP-LIGKLE-PKE-DAILDEDFEIGQILHDNVILKSIYYFTGEIN-----------------------DPYYHDFRDYGNRKYYK------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99457-1", "uniprot_id": "NP1L3_HUMAN", "id": "Q99457-1", "name": "Nucleosome assembly protein 1-like 3", "aln": "-------MAEADFKMVSEPVAHGVAEEEMASSTSDSGEESDSSSSSSSTSDSSSSSST-----------SGSSSGSGSSSSSSGSTSSRSRLYRKKRVPEPSRRARRAPLGTNFVDRLPQAVRNRVQALRNIQDECDKVDTLFLKAIHDLERKYAELNKPLYDRRFQIINAEYEP-TEEECEWNSEDEEFSSDEEVQDNTPSEMPPLEGEEEEN---------------PKENPEVKAEEKEVPKEIPEVKDEEKEVP--------------KEIPEVKAEEKADSKDCMEATPEVKEDPKEVPQVKADDKEQPKATEAKARAAVRETHKRVPEERLQDSVDLKRARKGKPKREDP-KGIPDYWLIVLKNVDKLGPMIQKYDEPILKFLSDVSLKFSKPGQPVSYTFEFHFLP--NPYFRNE--VLVKTYIIKAKPDHNDPFFSWGWEIEDCKGCKIDWRR-GKDVTVTTTQSRTTATG--EIEIQPRVVPNASFFNFFSPPEIP-MIGKLE-PRE-DAILDEDFEIGQILHDNVILKSIYYYTGEVN-----------------------GTYYQFGKHYGNKKYRK------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1G7-1", "uniprot_id": "Q9W1G7_DROME", "id": "Q9W1G7-1", "name": "", "aln": "----------------MDAPAEGHVDPESCNEIEDE-------------KSGSDCQSM----------------------------------------PAYMNSVMRRQYLQQMVKMLPAPVQNRIVFLKNLQLQHLNIEAQFFEDVYKLEQKYQVQYQPLFDKRREIIEGKVDP-AEEKPQWKE--PESSTDNEADAEH----------------------------------------------------------------------------------------------------------------------------------------------FREALSSLKSIPKDAKGIPGFWLTVFRNTAIMSEMVQPHDEPAIRKLIDISIKYDNG---HSYTLEFHFDK--NEYFSNS--VLTKQYVLKSTVDPNDPFAFEGPEIYKCTGCTINWEK-KMNLTVKTIRKKQKHKERGAVRTIVKQVPTDSFFNFFSPPEVP-SDQEEV-DDDSQQILATDFEIGHFLRARIIPKAVLYYTGDIVDDEDDEDEEEYDENEEDEYDDDDAPPPKGPKSAGIKKQSPNDCPNQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KW25-1", "uniprot_id": "Q7KW25_DROME", "id": "Q7KW25-1", "name": "Nucleosome assembly protein 1-like 4", "aln": "-------------MIGMADSAEGVTQEDSHTESRADGISGSLRSLGTYTQESTEPALS----------------------------------------PADLPARSRKAFLRHMIGQLAEPVQNRIRALRHNQLQQVRISEQFFREVYELERRFYGQSCALFDARRDILEGSVEPPIQTEKTWPEDPQDALYLDFGNNEE----------------------------------------------------------------------------------------------------------------------------------------------LRQLRQKLAPVSPTTLGVPRFWLTVFQNVPLLSELVQDHDEPLLESLMDVRLAYDQ----DSYMVIFQFRP--NSFLHDSSLLLTKRYFLQHSADPEYPFLFEGPEIVRCEGCHIHWRD-GSNLTLQTVESRRRNR----AHRVTKVMPRESFFRFFAPPQA--LDLSLA-DEKTKLILGNDFEVGFLLRTQIVPKAVLFYTGDLVDSLS-----------------AASPDSRSLSSEAEQEQVL------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAZ1-1", "uniprot_id": "Q9VAZ1_DROME", "id": "Q9VAZ1-1", "name": "", "aln": "----------------METVRN----------------------------------------------------------------------------RNPPRMKYTAPPKMESDLNFTEKEKKTLTELKQLYLETINLDVALQRDIYNIEKKYEDKHNIIFDKRKKILD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EFRKQNHGDVETNQSVPNFWLRVLK--ASYTEFISKRDEKILECLSDIRSRLYNEP-VVKFDIEFHFDP--NDYFTNT--VLTKTYFLNCLPDPDDPLAYDGAEIYKCEGCVIDWKQ-TKDQTKTE-------------------NQEPSFFEFFSPPLLP-EDTLDPNYCDVNAMLQNDFEVGFYLKERVIPKAVIFFTGEIADCQS-----------------SSGSETESEDTEDESDAEEEDGVDK------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25293-1", "uniprot_id": "NAP1_YEAST", "id": "P25293-1", "name": "Nucleosome assembly protein", "aln": "MSDPIRTKPKSSMQIDNAPTPHNTPASVLNPSYLKNGNPVRAQAQEQDDKIGTINEED------------------------------ILANQPLLLQSIQDRLGSLVGQDSGYVGGLPKNVKEKLLSLKTLQSELFEVEKEFQVEMFELENKFLQKYKPIWEQRSRIISGQEQPKPEQIAKGQEIVESLNETELLVDE-------------------------------------------------------------------------------------------------------------------------------------------------EEKAQNDSEEEQVKGIPSFWLTALENLPIVCDTITDRDAEVLEYLQDIGLEYLTDG-RPGFKLLFRFDSSANPFFTND--ILCKTYFYQKELGYSGDFIYD-----HAEGCEISWKDNAHNVTVDLEMRKQRNKTTKQVRTIEKITPIESFFNFFDPPKIQNEDQDEELEEDLEERLALDYSIGEQLKDKLIPRAVDWFTGAALEFEFEEDEEEADEDEDEEEDDDHGLEDDDGESAEEQDDFAGRPEQAPECKQS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. :: : *: : .:. : :..:*.:: ::: * *:. . .:* :** .:. : * :. * *: : . *:* * :: : :* * *. . . : . ** * *. : * ***.** ** . . * *:.:* *: .:: ::: ::** . ", "identical_positions": 34, "similar_positions": 65, "identity": "5.67%" }, { "cls_id": "homologset.agr.RGD:620991", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QX72-1", "uniprot_id": "SEBP2_RAT", "id": "Q9QX72-1", "name": "Selenocysteine insertion sequence-binding protein 2", "aln": "MASERPREPEGEDSIKLSADVKPFVPKFAGLNVAWSESSEACVFPGCAATYYPFVQESPAAEQKMYPEDMAFGAPAFPAQYVSSEIALHPFAYPTYALESTQSVCSVPTLQYDYSQAQCHPGFRPAKPRNEHACPP-QEAKCVFKKKSSDERRAWEEQKSSNRRADGAVPCEARPARGSCHL--------KSDGYHKRPDRKSRILTKSASTSKPEFEFSRLDFPELQSPKNSNLPETQKQPRWGPLGPAASNMSLLGEAGKPVADMVEGKMVKTDHTDGAVTNNAATSSPSCTRELSWTPMGYIVRQTVSSDSAAATETVNSIINLKKTTSSADAKNVSVTS-EALSSDPSFSREKR-VHPGPKAKASQGSELEQNESSKKNKKKKEKSKSSYEVLPVQEPPRIEDAEEFPNLSVASERRHRGESPKLQSKQQAQNDFKTGGKKSQVPVQLDLGGMLAALEK---QQHAPHAKPSSRPVVFSVGAVPVLSKDASSGERGRRSSQVKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERMQQRLQESAVSPTVASDDSQDVESGVTNQIPSPDNPTGPEKTEEPMSSTPVVEGESEEPAGTEFQRDPEACQPAPDSATFPKIHSRRFRDYCSQMLSKEVDACVTGLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLRKLKCIIISPNCEKTQSKGGLDDTLHTIIDCACEQNIPFVFALNRKALGRSLNKAVPVSIVGIFSYDGAQDQFHKMVELTMAARQAYKTMLETMRQEQAGEPGPQTPPSPPMQDPIQSTDEGTLASTG-EEPHYIEIWRKHLEAYSQHALELEDSLEASTSQMMNLNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U1C4-1", "uniprot_id": "SEBP2_MOUSE", "id": "Q3U1C4-1", "name": "Selenocysteine insertion sequence-binding protein 2", "aln": "MASERPREPDGEDSIKLSADVKPFVPKFAGLNVAWSESSETRVFPGCAATYYPFVQEPPAAEQKMYPEDMAFGAPTFPAQYVSSEIALHPFAYPTYTLESAQSVCSVPTLQYDYSQARCHPGFRTAKPRHEHVCPPPQEAKGVFKKKPSDERRACEEQKSSSRRADNAVPCEARPARGSSHLSSRTESSLKSDGYHKRPDRKSRILAKSASTSKPEFEFSRLDFPELQSPKNSNMPETQKPPRWGPLGPAASNMPLLGDVGKPVADMVEGKMVKSDHTDGAVTSNATTSSPSCTQELSWTPMGYIVRQTVSSDSAAATENVTSMINLKKTTSSADAKNVSVTS-EALSSNPSYNREKR-VYPAPKAKASQGGELEQNESSKKNKKKKEKSKPSYEVLTVQEPPRIEDAEEFPNLSVASERRHRGQSPKLHSKQQTQNEFKTSGKKSQVPVQLDLGGMLAALEKQQQQQHASHAKPSSRPVVFSVGAVPVLSKDASSSERGRRSSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERMQQRLQESAVSLTVASDDSQDVESGASNQTPSQDNPTGPEKTEESVSSTPVVEGESEEPAGTEFQRDPEACQPAPDSATFPKIHSRRFRDYCSQMLSKEVDACVTGLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLRKLKCIIISPNCEKTQSKGGLDDTLHTIIDCACEQNIPFVFALNRKALGRSLNKAVPVSIVGIFSYDGAQDQFHKMVELTMAARQAYKTMLETMRQEQAGEPGPQSPPSPPMQDPIPSTEEGTLPSTG-EEPHYIEIWKKHLEAYSQRALELEDSLEASTSQMMNLNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96T21-1", "uniprot_id": "SEBP2_HUMAN", "id": "Q96T21-1", "name": "Selenocysteine insertion sequence-binding protein 2", "aln": "MASEGPREPESE-GIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTEQKIYTEDMAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAEN-NMSEIQKQPKWGPVHSVSTDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEK---KQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQER-KQRLQENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELIS-TPSVEDKSEEPPGTELQRDTEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQMMNLNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSH1-1", "uniprot_id": "Q9VSH1_DROME", "id": "Q9VSH1-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEKIRRSRNQDVQDTAIKITPRS-----------------------------------------------------SKYKNQHRKREQQTSLLDFVIKPRPKTQRQTKAHKLQKTHLAITRGSYIVYKPKGKTRLDPKKKITRLKKSVRVYR----------------TSKKAEREVAENDLEGVPVVGQDINPN------------------AIPLEQQVQNLSLSKTPAPN-------------------------------------------------------------------------------------NPSQAKTVHAIHSRRFRSYCDNCTRPRLKELSTQLLRDLDRFQKRAFAKNEIKARAHPRLVLGVREALARLRINKVKLLFLATDCEICPGESGLDATIEGLKFQCQQQQVPYCFPLLRRELSYALQKRAQICCVAILDFDGANATYADLLNEIEDARAEYKRRTAS---------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :*:: . : :. .:.. :. **:::*.:. .. : :: *: : : :* : * . :.* :.: : *. .: : .*:: * . . . .: .***:.:: .. : ** :: :: .:.*: *. ..: *. *******.**.: .:. * **::* ***.* : *: :**::: *****:**.* :*::.*:* ::::.:** .:.*** *:. : . :*::*: *.* *: *. :*:* . :. *.*:.:***: : .::: ** ** . ", "identical_positions": 74, "similar_positions": 127, "identity": "8.59%" }, { "cls_id": "homologset.agr.RGD:620992", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1W6-1", "uniprot_id": "LYRIC_RAT", "id": "Q9Z1W6-1", "name": "Protein LYRIC", "aln": "MAARSWQDELAQQAEEGSARLRELLSVGLGFLRTELGLDLGLEPKRYPSWVILVGTGALGLLLLFLLGYGWAAACAGARKKRRSPPRKREEVTP-PTPAPEDPAQLKNLRSEEQKKKNRKKLPEKPKPNGRTVEIPEDEVVRTPRSITAKQPPETDKKNEKSKKNKKKSKSDAKAVQNSSRHDGKEVDEGAWETKISHREKRQQRKRDKVLTDSGSLDSTIPGIENTITVTTEQLTTASFPVGSKKNKGDSHLNVQVSNFKSGKGDSTLQVSSGLNENITVNGGGWSEKSVKLSSQLSAGEEKWNSVPPASAGKRKTEQSAWTQDPGDTNANGKDWGRNWSDRSIFSGIGSTAEPVSQSTTSDYQWDGSRNQPHIDDEWSGLNGLSSADPSSDWNAPAEEWGNWVDEDRASLLKSQEPISNDQKDSDDDKEKGEGALPTGKSKKKKKKKKKQGEDNSITQDTEDLEKDTREELPVNTSKARPKQEKACSLKTMSTSDPVEVLIKNSQPIKTLPPAISAEPSVTLSKGDSDKSSSQVPPMLQDTDKPKSNAKQNSVPPSQTKSETNWESPKQIKKKKKARRET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WJ7-1", "uniprot_id": "LYRIC_MOUSE", "id": "Q80WJ7-1", "name": "Protein LYRIC", "aln": "MAARSWQDELAQQAEEGSARLRELLSVGLGFLRTELGLDLGLEPKRYPGWVILVGTGALGLLLLFLLGYGWAAACAGARKKRRSPPRKREEAAP-PTPAPDDLAQLKNLRSEEQKKKNRKKLPEKPKPNGRTVEVPEDEVVRNPRSITAKQAPETDKKNEKSKKNKKKSKSDAKAVQNSSRHDGKEVDEGAWETKISHREKRQQRKRDKVLTDSGSLDSTIPGIENIITVTTEQLTTASFPVGSKKNKGDSHLNVQVSNFKSGKGDSTLQVSSRLNENLTVNGGGWSEKSVKLSSQLS--EEKWNSVPPASAGKRKTEPSAWTQDTGDTNANGKDWGRNWSDRSIFSGIGSTAEPVSQSTTSDYQWDVSRNQPYIDDEWSGLNGLSSADPSSDWNAPAEEWGNWVDEDRASLLKSQEPISNDQKVSDDDKEKGEGALPTGKSKKKKKKKKKQGEDNSHTQDTEDLEKDTREELPVNTSKARPKQEKACSLKTMSTSDPAEVLIKNSQPVKTLPPAISAEPSITLSKGDSDNSSSQVPPMLQDTDKPKSNAKQNSVPPSQTKSETNWESPKQIKKKKKARRET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UE4-1", "uniprot_id": "LYRIC_HUMAN", "id": "Q86UE4-1", "name": "Protein LYRIC", "aln": "MAARSWQDELAQQAEEGSARLREMLSVGLGFLRTELGLDLGLEPKRYPGWVILVGTGALGLLLLFLLGYGWAAACAGARKKRRSPPRKREEAAAVPAAAPDDLALLKNLRSEEQKKKNRKKLSEKPKPNGRTVEVAEGEAVRTPQSVTAKQPPEIDKKNEKSKKNKKKSKSDAKAVQNSSRHDGKEVDEGAWETKISHREKRQQRKRDKVLTDSGSLDSTIPGIENTITVTTEQLTTASFPVGSKKNKGDSHLNVQVSNFKSGKGDSTLQVSSGLNENLTVNGGGWNEKSVKLSSQISAGEEKWNSVSPASAGKRKTEPSAWSQDTGDANTNGKDWGRSWSDRSIFSGIGSTAEPVSQSTTSDYQWDVSRNQPYIDDEWSGLNGLSSADPNSDWNAPAEEWGNWVDEERASLLKSQEPIPDDQKVSDDDKEKGEGALPTGKSKKKKKKKKKQGEDNSTAQDTEELEKEIREDLPVNTSKTRPKQEKAFSLKTISTSDPAEVLVKNSQPIKTLPPATSTEPSVILSKSDSDKSSSQVPPILQETDKSKSNTKQNSVPPSQTKSETSWESPKQIKKKKKARRET", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********************:************************.******************************************.:. *:.**:* * *****************.***********:.*.*.**.*:*:****.** *********************************************************************** ********************************************** ****:*******.*********:* *******.********** ***:**.**:*:*******.**************************** *****:****************.****************:***********.:*** ******************************** :****:***: **:*******:******* ****:*****.***:*****:****** *:***: ***.***:*******:**:***.***:**************.*****************", "identical_positions": 517, "similar_positions": 49, "identity": "88.83%" }, { "cls_id": "homologset.agr.RGD:620993", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPJ0-1", "uniprot_id": "NUCKS_RAT", "id": "Q9EPJ0-1", "name": "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1", "aln": "MSRPVRNRKVVDYSQFQESDDADEDYGRDSGPPAKKIRSSPREAKNKRRSGKNSQEDSEDSEEKDVKTKKDDSHSAEDSEDEKDDHKSVRQQRQAASKAASKQREMLLEDVGSEEEPEEDDEAPFQEKDSGSDEDFLMEDDDDSDYGSSKKKNKKMVKKSKPERKEKKMPKPRLKATVTPSPVKGKGKVGRPTASKTSKEKTPSPKEEDEEAESPPEKKTSASPPLEKSGDEGSEDEAASGED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XU3-1", "uniprot_id": "NUCKS_MOUSE", "id": "Q80XU3-1", "name": "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1", "aln": "MSRPVRNRKVVDYSQFQESDDADEDYGRDSGPPAKKIRSSPREAKNKRRSGKNSQEDSEDSEEKDVKTKKDDSHSAEDSEDEKDDHKNVRQQRQAASKAASKQREMLLEDVGSEEEPEEDDEAPFQEKDSGSDEDFLMEDDDDSDYGSSKKKNKKMVKKSKPERKEKKMPKPRLKATVTPSPVKGKAKVGRPTASKKSKEKTPSPKEEDEEAESPPEK---------KSGDEGSEDEASSGED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1E3-1", "uniprot_id": "NUCKS_HUMAN", "id": "Q9H1E3-1", "name": "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1", "aln": "MSRPVRNRKVVDYSQFQESDDADEDYGRDSGPPTKKIRSSPREAKNKRRSGKNSQEDSEDSEDKDVKTKKDDSHSAEDSEDEKEDHKNVRQQRQAASKAASKQREMLMEDVGSEEEQEEEDEAPFQEKDSGSDEDFLMEDDDDSDYGSSKKKNKKMVKKSKPERKEKKMPKPRLKATVTPSPVKGKGKVGRPTASKASKEKTPSPKEEDEEPESPPEKKTSTSPPPEKSGDEGSEDEAPSGED", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********************************:****************************:********************:***.*******************:******** **:******************************************************************.********* **************.****** ***********.****", "identical_positions": 223, "similar_positions": 9, "identity": "91.77%" }, { "cls_id": "homologset.agr.RGD:620994", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R193-1", "uniprot_id": "AT1B4_RAT", "id": "Q9R193-1", "name": "Protein ATP1B4", "aln": "MRRQLRSRRAPAFPYGYRYRLDDQDEMNHNYLADEEEEAEEEAQVMMVPGLEEEEEEEE-GKEEEEEREEEEGQGQSTGNAWWRKLQIVNEYLWDPEKRMSLARTGQSRSLILVIYFFFYASLAAVITLFIYMLFLAISPYMPTFTEQ----VKPPGVMIRPFAHSLNFN-----FNVSEPETWQRYVISLNGFLQGYNDSLQEEMNIDCPPGQYFIQDGDEDEDKKACQFKRSFLKNCSGLEDPTFGYSTGQPCILLKMNRIVGFRPEFG-----------------------------DPVKVSCKVQKG-DENDIRSINYYPESASFDLRYYPYYGKLTHVNYTSPLVAMHFTDVVKNQEVPVQCQLKGKGIVNDVINDRFVGRIIFTLNIET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99ME6-1", "uniprot_id": "AT1B4_MOUSE", "id": "Q99ME6-1", "name": "Protein ATP1B4", "aln": "MRRQLRSRRAPAFPYGYRYRLDDQDEANHNYLADEEEEAEEEAQVMMVPGLEEEEEEEE-GKEEEEEREEEEGQGQSTGSAWWRKLQIVNEYLWDPEKRMSLARTGQSRSLILVIYFFFYASLAAVITLFIYMLFLAISPYMPTFTEQ----VKPPGVMIRPFAHSLNFN-----FNVSEPETWQRYVISLNGFLQGYNDSLQEEMNIDCPPGRYFIQDGDEDEDKKACQFKRSFLKNCSGLEDPTFGYSTGQPCILLKMNRIVGFRPEFG-----------------------------DPVKVSCKVQKG-DENDIRSINYYPESASFDLRYYPYYGKLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGIVNDVINDRFVGRIIFTLNIET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UN42-1", "uniprot_id": "AT1B4_HUMAN", "id": "Q9UN42-1", "name": "Protein ATP1B4", "aln": "MRRQLRSRRAPSFPYSYRYRLDDPDEANQNYLADEEEEAEEEARVTVVPKSEEEEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLILLIYFFFYASLAAVITLCMYTLFLTISPYIPTFTER----VKPPGVMIRPFAHSLNFN-----FNVSEPDTWQHYVISLNGFLQGYNDSLQEEMNVDCPPGQYFIQDGNEDEDKKACQFKRSFLKNCSGLEDPTFGYSTGQPCILLKMNRIVGFRPELG-----------------------------DPVKVSCKVQRG-DENDIRSISYYPESASFDLRYYPYYGKLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNIET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24048-1", "uniprot_id": "ATPB2_DROME", "id": "Q24048-1", "name": "Sodium/potassium-transporting ATPase subunit beta-2", "aln": "-------------------------------------------------------------MPTITEDCIDGFQQYYSRPPERPKKKSLKQMVYDSEDNSYFGRSMDSWAKIGIFYVAFYGVLAALVAICMWAFFQTLDPRIPKWTLDRSLIGTNPGLGFRPLPPVDNVESTLIWYKGTQHENYKHWTDSLDDFLAVYKVPGLTPG---RGQNIYNCDYNQPPPKGQVCDVDIKTWSPCT--KENNYSYHKSAPCIFLKLNKIYGWIPEYYNRSNDLPANMPASLKTYIAEVEKTQPEKLNTIWVSCEGENPADQENIGAVNYLPIRG-FPGYFYPYQ---NSEGYLSPLVAVHFQRPKRGIIINVECRAWARNIIHD--RKERIGSVHYELLID-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PDX8-1", "uniprot_id": "M9PDX8_DROME", "id": "M9PDX8-1", "name": "", "aln": "----------------------------------------------------------------MADKKIG---EYYAPPVKMGKWEGFKKFLWNSETSQCLGRTGSSWAKILLFYIIFYAALTGFFAAIFTVFYQTLDNEKPKWMLDNGLIGSNPGLGFRPMPPEANVESTLVWYESSKKDNYKYWVDETSRFLKYHTYQDLEK------QNQVNCSFEHPPQDDKVCGIDFSSFSPCT--ADNNFGYHVARPCIFLKLNKIYNWIPEIYNDSKTLPDHMPEELKQHIKEKQSLRPNETNVVWVSCEGENPADVENIKARDYYPRMG-FPRYYFPFK---NIQGYIPPIVAVQFT-VETGVLINIECKAWARNINHD--RSDRRGSVHFELMVD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24046-1", "uniprot_id": "ATPB1_DROME", "id": "Q24046-1", "name": "Sodium/potassium-transporting ATPase subunit beta-1", "aln": "----------------------------------------------------------------MSKNNGKGAKGEFEFP-QPAKKQTFSEMIYNPQEGTFFGRTGKSWSQLLLFYTIFYIVLAALFTICMQGLLSTISDTEPKWKLQDSLIGTNPGLGFRPLS-EQTERGSVIAFDGKKPAESDYWIELIDDFLRDYNHTEGRD--------MKHCGFGQVLEPTDVCVVNTDLFGGCS--KANNYGYKTNQPCIFLKLNKIFGWIPEVYDKEE---KDMPDDLKKVINET---KTEERQQVWVSCNGHLGKDKENFQNIRYFPSQG-FPSYYYPFL---NQPGYLSPLVAVQFNSPPKGQMLDVECRAWAKNIQYSGSVRDRKGSVTFQILLD-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : ..: :::.: :.*: .* : : ::* ** *:...: : : ::. *.: . **: :**:. . . :. .: . : . ** :. . ..* .. . *: .:.* ***:**:*:* .: ** : : ***: . * ::: * * . * ::*: . .* .*:**::* . : ::*: .:.: . * : : : :: ", "identical_positions": 41, "similar_positions": 93, "identity": "10.35%" }, { "cls_id": "homologset.agr.RGD:620995", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54735-1", "uniprot_id": "PDE5A_RAT", "id": "O54735-1", "name": "cGMP-specific 3',5'-cyclic phosphodiesterase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPFG------------------------------------------DKTRDMVNAWFSERVHNIPVCKEGIRAHTESCSCSLPQSPH----ADNTTPGAPARKISASEFDR-PLRPIVVKDSEGTVSFLSD--------------------------------SGKKEQMPLTSPR--------------FDSDEGDQCSR------------------------------------------LLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLVCEDSSK----DKFLVSRLFDVAEGSTLEEA-SNNCIRLEWNKGIVGHVAAFGEPLNIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCPDSFSRVFQMEWEEVGK--SSEPLTREHDANKINYMYAQYVKNTMEPLNIPDVTKDNRFPWTNENMGHINTHCIRSLLCTPIKNGKKNKVIGVCQLVNKMEEKTGKIKAFNQNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQALAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLETLALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSTMEHHHFDQCLMVLNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNEFSFEDPLQKELFLAMLMTACDLSAITKPWPIQQRIAELVAAEFFDQGDRERKELNMEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCLPLLDGCRKNRQKWQALADQ-QEKTLLNGESGQAKRD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CG03-1", "uniprot_id": "PDE5A_MOUSE", "id": "Q8CG03-1", "name": "cGMP-specific 3',5'-cyclic phosphodiesterase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERAGPNS----------VRSQQQRDPDWVEAWLDDHRDFTFSYFIRKATRDMVNAWFSERVHNIPVCKEGIRAHTESCSCSLQQSPH----ADNTTPGAPARKISASEFDR-PLRPIVVKDSEGTVSFLSD--------------------------------SGKKEQMPLTPPR--------------FDSDEGDQCSR------------------------------------------LLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLVCEDSSK----DKFLISRLFDVAEGSTLEEA-SNNCIRLEWNKGIVGHVAAFGEPLNIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCPDSFSRVFHMECEEVGK--PSDPLTREQDANKINYMYAQYVKNTMEPLNIPDVTKDKRFPWTNENMGHVNTPCIGSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKIKAFNQNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQALSAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLETLALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIDEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFSFEDPLQKELFLAMLMTACDLSAITKPWPIQQRIAELVAAEFFDQGDRERKELNMEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCLPLLDGCRKNRQKWQALAEQ-QEKMLLNGESSQGKRD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76074-1", "uniprot_id": "PDE5A_HUMAN", "id": "O76074-1", "name": "cGMP-specific 3',5'-cyclic phosphodiesterase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERAGPSFGQQRQQQQPQQQKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAERVHTIPVCKEGIRGHTESCSCPLQQSPR----ADNSAPGTPTRKISASEFDR-PLRPIVVKDSEGTVSFLSD--------------------------------SEKKEQMPLTPPR--------------FDHDEGDQCSR------------------------------------------LLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLVCEDSSN----DKFLISRLFDVAEGSTLEEV-SNNCIRLEWNKGIVGHVAALGEPLNIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCSDSFSSVFHMECEELEK--SSDTLTREHDANKINYMYAQYVKNTMEPLNIPDVSKDKRFPWTTENTGNVNQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQ-QEKMLINGESGQAKRN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BE10-1", "uniprot_id": "A0A8M2BE10_DANRE", "id": "A0A8M2BE10-1", "name": "Phosphodiesterase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVYPSDS------------------ERMMEAWLDDNLEFAHSYFVRKASREMVNAWFAERVHSIQPSREPSKAVPEPVTAVHSLGPTDVVPSSSPAPSTPTRKISASEFDR-PLRPIVVKDAEGSFTFLSD--------------------------------TER-VQMPLPPSQRPGSDNGTDEGGGIRDRGNGDRCAR------------------------------------------LLELVRDVSSHLDLTALCHKIFLHTHELIAADRYSLFLVGEDSSN----RKFLVSRLFDVAEGSTLEES-SNSGIRLEWNKGIVGYVAATGQPLNIKNAYEDSRFNAEVDQITGYKTQSILCLPIKNHRDEVVGVAQAINKKCGENSTFTEQDEKDFSSYLAFSGIVLHNAQLYETSQLENRRNQVLLDLASLIFEEQQSLEVLLRKTVATILSFMQAQECTVFISDRETANTFASVFHMEYEEIAG--STDFPNRECDVNKINYMYAQYVKNTMETLNITDTTKDQLFSWTSEDPQSTNCQ-IKSLLCTPIRNGKKDKVIGVCQLVNKMDEASGEVKAFNRNDEQFLEAFAVFCGLGIQNTQMYEAVERAMAKQEVTLEVLSYHASAAEEETRALQVTAAATIPSAQSLRLMDYSFSDFDLTDAETTQATIRMFVDLKLVQNFQIKYKSLCQWILSVKKNYRKNVVYHNWRHAFNTSQCMFAVLKSGRVQNNLSDLETLALMIATLSHDLDHRGVNNSYIKRSDHPLAQLYCHSTMEHHHFDQCLMILNSPGNQILSGLSLDEYKATLKMIEKAILATDLAVYMKKRTEFFELAKNSQFEWEDDCHRDLLRSMLMTACDISAITKPWPVQKKIAELVATEFFEQGDKERRELNIEPIDLMNREKQDKIPSMQVSFIDAICTQLYEALTGISEFCSPLLEGCRKNRQNWKILAEQGEEAALLNGEL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ79-1", "uniprot_id": "PDE11_DROME", "id": "Q9VJ79-1", "name": "Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11", "aln": "MGQAASMCRFRGCRYKNKNKSSKQQQQQQQQQQQQQQQHQQQQQQTPSHSPQIQHHSEIIPATTGLHLRSIEEPATTPLQFQPTGRMNTEQGGTGYGGYGSSEHSLLIATRHAGVPLPLAQHQPLPAHYQPLNHSGAAPPSSSNGSSSSGGGVQTSATPQQQQQYQVQQPYQYQYQHHYHHQANSPQHHRPYDPEHARMEAWLDENQEFVQDYFIRKATRQTVDAWLVS--HATSAGNDVVSSTSPTHANGQTSSSR-----GGSGATTPVRKISAHEFERGGLLKPIVNTIDGTPTFLSIGPPMDNGSVGGSCSNLQNVGGVVAGQYQYNHQQHHHNHAHLHHSQHSHYQAGGAVGSSSLGSTGGASGAGGAPSLGGSGGAGNGHQYPYYHCHQRPQRLSRNELKQLDEKELIFELVKDICNELEVRTLCHKILQNVSILLNADRGSLFLVQGRCNGPDGLKKCLVSKLFDVCPRSTVEEMEQQDEVRVAWGTGIAGHVAESGEPVNIPDAYQDERFNCEIDSLTGYRTKALLCMPIKDSSGDVIGVAQVINKMNG--ECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRILTHMQSLIQCQRVQILLVHEADKGSFSRVFDFEANDLSEEEATSRTSPYESRFPINIGITGHVATTGETVNVPNAYEDDRFDASVDEN---SCFKHRSILCMAIKN-SLGQIIGVIQLINKFNELD-----FTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLR---VPSAVHFRLHDFKFDDIHFEDDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYR-NVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYSTSTMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTDLAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKLEPLVEGVRDNRGHWIDLADVVKTKTSQDQEPEEEQQQQNVISNGDCKAMSDDDVAASEAEVAVDSPSEKASVNGSNVANNSSNTNKKIAVASHPTSTQPSDDDNDVDADADDVDEQAAEENGHDAEVDEASCRSNSTCSSSTASSCLSTPPPTGEDDSTPVSPLKTLQAKLVAANLNALQRQTSNQAQTQKQRCKSCDHSRSGLQVRKTSSLRGAQELDLDSKTRNGTHAALCKSTPVINNHSHHHNHSHSHNHNHHHHHHHHSHHNHSQHGIGIGSASIGGSGLISLTTPLLAMDSDRIPKIVGKIGNLDGLPFANGIGGPQNGHGLPFGSYQHHHHHQHHHHLLARRHSETNSNGATAMAVEK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*: *:**: . * .: . . . : .. ... . :*.***** **:* * :*: :*: :*** : : * .: . * : ::***:*:...*:: :*****: : *: *** ***** .. * *:*:****. **:** .:. :*: *..**.*:** *:*:** :**:* ***.*:*.:***:*:::**:***: :*:****.*** * *:* *** *::** *.** *:******.* ** :********* :*****.::* :: : : : *::* *. ::: .. .:*: **.:* ::: .:. . . ** : :* .* *.:*:.:. :*. * : :: . *:** .*:* . .::*** **:**::* *.:***:*:***.:***:**:**:*** . ***** ************: :*:: *: :*** ::: *:.*.*:.: * :* . :*** **.:*:.*::.:: **:*:******** **.*********.:* *** *.: : : : ::* ***:*. *.*******.***: ::. ******. * ***********:*********:.** ::* .:::::.***:****:*:*:* *:* : : *: :* **.**:******* :::::*:**::***:*** *::***: * *:*****::::* ***.***:** :***:: :*: **::* *.** :* **: : : * ", "identical_positions": 346, "similar_positions": 251, "identity": "23.49%" }, { "cls_id": "homologset.agr.RGD:620996", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4QR99-1", "uniprot_id": "TGT_RAT", "id": "Q4QR99-1", "name": "Queuine tRNA-ribosyltransferase catalytic subunit 1", "aln": "MAAVGSPGSLESAPRIMRLVAECSRSRARAGELRLPHGTVATPVFMPVGTQATMKGITAEQLDSLGCRICLGNTYHLGLRPGPELIQKAHGLHGFMNWPHNLLTDSGGFQMVSLISLSEVTEEGVRFRSPYDGEETLLSPERSVEIQNALGSDIIMQLDDVVSSTVTGPRVEEAMHRSVRWLDRCIAAHKRQDKQNLFAIIQGGLNADLRTTCLKEMTKRDVPGFAIGGLSGGESKEQFWKMVALSTSMLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVYPTRTARFGSALVPTGNLQLKKQQYAKDFSPINPECPCATCQTHSRAFLHTLLHSDNTAALHHLTVHNIAYQLQLLSAARSSILEQRFPDFVRNFMRTMYGDHSLCPAWAIEALASVGITLT--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JMA2-1", "uniprot_id": "TGT_MOUSE", "id": "Q9JMA2-1", "name": "Queuine tRNA-ribosyltransferase catalytic subunit 1", "aln": "MAAVGSPGSLESAPRIMRLVAECSRSGARAGELRLPHGTVATPVFMPVGTQATMKGITTEQLDSLGCRICLGNTYHLGLRPGPELIRKAQGLHGFMNWPHNLLTDSGGFQMVSLFSLSEVTEEGVHFRSPYDGEETLLSPERSVEIQNALGSDIIMQLDHVVSSTVTGPLVEEAMHRSVRWLDRCIAAHKHPDKQNLFAIIQGGLNADLRTTCLKEMTKRDVPGFAIGGLSGGESKAQFWKMVALSTSMLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVYPTRTARFGSALVPTGNLQLKKKQYAKDFSPINPECPCPTCQTHSRAFLHALLHSDNTTALHHLTVHNIAYQLQLLSAVRSSILEQRFPDFVRNFMRTMYGDHSLCPAWAVEALASVGIMLT--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXR0-1", "uniprot_id": "TGT_HUMAN", "id": "Q9BXR0-1", "name": "Queuine tRNA-ribosyltransferase catalytic subunit 1", "aln": "MAGAATQASLESAPRIMRLVAECSRSRARAGELWLPHGTVATPVFMPVGTQATMKGITTEQLDALGCRICLGNTYHLGLRPGPELIQKANGLHGFMNWPHNLLTDSGGFQMVSLVSLSEVTEEGVRFRSPYDGNETLLSPEKSVQIQNALGSDIIMQLDDVVSSTVTGPRVEEAMYRSIRWLDRCIAAHQRPDKQNLFAIIQGGLDADLRATCLEEMTKRDVPGFAIGGLSGGESKSQFWRMVALSTSRLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVFPTRTARFGSALVPTGNLQLRKKVFEKDFGPIDPECTCPTCQKHSRAFLHALLHSDNTAALHHLTVHNIAYQLQLMSAVRTSIVEKRFPDFVRDFMGAMYGDPTLCPTWATDALASVGITLG--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYK1-1", "uniprot_id": "TGT_DANRE", "id": "Q7SYK1-1", "name": "Queuine tRNA-ribosyltransferase catalytic subunit 1", "aln": "MASVKAVSS--AAPLALRIVAECPVSKARACSLTLPHCAVNTPVFMPVGTQGTMKGITADQLEDLDCQICLGNTYHLGMRPGPDLIEKANGLHGFMKWRRNLLTDSGGFQMVSLVELSEVTEEGVTFRSPYDGKEILLTPEQSIAIQNSLGSDIMMQLDDVVSSTVKGPRVEEAMHRSVRWLDRCIAANKNPDRQNLFAIIQGGLDAELRKACLKEMTKRDVPGFAIGGLGGGEEKDDFWKMVTLSTDHLPREKPRYLMGVGYAVDLVVCVALGCDMFDCVFPTRTARFGSALVPWGSLQLKQKQYAKDFQPIDPDCQCPTCRRHSRAYLHALFKSD-TAAMHHITIHNISYQLSLMRSVRQSIIDQRFPEFVKEFMKRMFPSSSQYPSWAVEALQSVNICLS--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPY8-1", "uniprot_id": "TGT_DROME", "id": "Q9VPY8-1", "name": "Queuine tRNA-ribosyltransferase catalytic subunit", "aln": "------MGPSHIPPLTYKVVAECSVSKARAGLMTLRHSEVNTPVFMPVGTQGTLKGIVPDQLIELNCQILLGNTYHLGLRPGIETLKKAGGLHKFMGWPRAILTDSGGFQMVSLLQLAEIDEHGVNFRSPFDNSQCMLTPEHSIEIQNAIGGDIMMQLDDVVKTTTTGPRVEEAMERTIRWVDRCIEAHARDDDQSLFPIVQGGLDVPLRQRCVSALMERQVRGFAVGGLSGGESKHDFWRMVDVCTGYLPKDKPRYLMGVGFAADLVVCVALGIDMFDCVFPTRTARFGCALVDSGQLNLKQPKYKLDMEPIDKDCDCSTCRRYTRSYLHHIATNESVSSS-LLSIHNVAYQLRLMRSMREAIQRDEFPQFVADFMARHFKAEP-VPAWIREALSAVNIQLPADPERIDEQDQKPKTEKRRETEDVAEEQVASS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .* ::****. * *** : * * * **********.*:***..:** *.*:* ********:*** : :.** *** ** * : :************..*:*: *.** ****:*..: :*:**:*: ***::*.**:****.**.:*..** ***** *::**:**** *: . * *.**.*:****:. ** *:. : :*:* ***:***.***.* :**:** :.*. **::*********:*.********* ******:********.*** *.*:*:: : *: **: :* *.**: ::*::** : .: .:: :::**::*** *: : * :* ..**:** :** : . *:* :** :*.* * ", "identical_positions": 205, "similar_positions": 109, "identity": "47.13%" }, { "cls_id": "homologset.agr.RGD:620997", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MP3-1", "uniprot_id": "CALCB_MOUSE", "id": "Q99MP3-1", "name": "Calcitonin gene-related peptide 2", "aln": "MDFWKFFPFLALSTIWVLCLASSLQAAPFRSALESSLDLGTLGDQEKHLLLAALMQDYEQMKARKLEQEEQETKGSR------VTAQKRSCNTATCVTHRLADLLSRSGGVLKDNFVPTDVGSEAFGRRRRRDLQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10093-1", "uniprot_id": "CALCB_RAT", "id": "P10093-1", "name": "Calcitonin gene-related peptide 2", "aln": "MDFWKFFPFLALSSMWVLCLASSLQAAPFRSALESSLDLGTLSDQEKHLLLAALIQDYEQ-KARKLEQEEQETEGSRKGSSSSVISQKRSCNTATCVTHRLAGLLRRSGGVVKDNFVPTNVGSKAFGRRRR-DLRV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10092-1", "uniprot_id": "CALCB_HUMAN", "id": "P10092-1", "name": "Calcitonin gene-related peptide 2", "aln": "MGFRKFSPFLALS-ILVLYQAGSLQAAPFRSALESSPDPATLSKEDARLLLAALVQDYVQMKASELKQE-QETQGSS------SAAQKRACNTATCVTHRLAGLLSRSGGMVKSNFVPTNVGSKAFGRRRR-DLQA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* ** ****** : ** *.************** * .**..:: :******:*** * ** :*:** ***:** :***:************.** ****::*.*****:***:******* **:.", "identical_positions": 89, "similar_positions": 23, "identity": "65.44%" }, { "cls_id": "homologset.agr.RGD:620998", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2VWQ2-1", "uniprot_id": "NELL1_MOUSE", "id": "Q2VWQ2-1", "name": "Protein kinase C-binding protein NELL1", "aln": "MPMDVILVLWFCVCTARTVLGFGMDPDLQMDIITELDLVNTTLGVTQVAGLHNASKAFLFQDVQREIHSAPHVSEKLIQLFRNKSEFTFLATVQQKPSTSGVILSIRELEHSYFELESSGPREEIRYHYIHGGKPRTEALPYRMADGQWHKVALSVSASHLLLHVDCNRIYERVIDPPETNLPPGSNLWLGQRNQKHGFFKGIIQDGKIIFMPNGFITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAETRLGQLENCHCEKTCQVSGLLYRDQDSWVDGDNCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHISGQCCKVCRPKCIYGGKVLAEGQRILTKTCRECRGGVLVKITEACPPLNCSEKDHILPENQCCRVCRGHNFCAEAPKCGENSECKNWNTKATCECKNGYISVQGNSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCIPGYIRVDDFSCTEHDDCGSGQHNCDKNAICTNTVQGHSCTCQPGYVGNGTVCKAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECAEGFVECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWILREDRCSVCSCKDGKIFCRRTACDCQNPNVDLFCCPECDTRVTSQCLDQSGQKLYRSGDNWTHSCQQCRCLEGEADCWPLACPSLSCEYTAIFEGECCPRCVSDPCLADNIAYDIRKTCLDSSGISRLSGAVWTMAGSPCTTCQCKNGRVCCSVDLVCLENN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62919-1", "uniprot_id": "NELL1_RAT", "id": "Q62919-1", "name": "Protein kinase C-binding protein NELL1", "aln": "MPMDVILVLWFCVCTARTVLGFGMDPDLQLDIISELDLVNTTLGVTQVAGLHNASKAFLFQDVQREIHSAPHVSEKLIQLFRNKSEFTFLATVQQKPSTSGVILSIRELEHSYFELESSGPREEIRYHYIHGGKPRTEALPYRMADGQWHKVALSVSASHLLLHIDCNRIYERVIDPPETNLPPGSNLWLGQRNQKHGFFKGIIQDGKIIFMPNGFITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAETRLGQLENCHCEKTCQVSGLLYRDQDSWVDGDNCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHISGQCCKVCRPKCIYGGKVLAEGQRILTKTCRECRGGVLVKITEACPPLNCSAKDHILPENQCCRVCPGHNFCAEAPKCGENSECKNWNTKATCECKNGYISVQGNSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDDCGSGQHNCDKNAICTNTVQGHSCTCQPGYVGNGTICKAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECAEGFVECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWILREDRCSVCSCKDGKIFCRRTACDCQNPNVDLFCCPECDTRVTSQCLDQSGQKLYRSGDNWTHSCQQCRCLEGEADCWPLACPSLGCEYTAMFEGECCPRCVSDPCLADNIAYDIRKTCLDSFGVSRLSGAVWTMAGSPCTTCKCKNGRVCCSVDLECIENN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92832-1", "uniprot_id": "NELL1_HUMAN", "id": "Q92832-1", "name": "Protein kinase C-binding protein NELL1", "aln": "MPMDLILVVWFCVCTARTVVGFGMDPDLQMDIVTELDLVNTTLGVAQVSGMHNASKAFLFQDIEREIHAAPHVSEKLIQLFRNKSEFTILATVQQKPSTSGVILSIRELEHSYFELESSGLRDEIRYHYIHNGKPRTEALPYRMADGQWHKVALSVSASHLLLHVDCNRIYERVIDPPDTNLPPGINLWLGQRNQKHGLFKGIIQDGKIIFMPNGYITQCPNLNHTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAETRLSQLENCHCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAGSPCTTCKCKNGRVCCSVDFECLQNN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:***:**********:*********:**::***********:**:*:***********::****:*******************:******************************* *:********.********************************:*************:****** ************:****************:********:************************************.****************************:********************************:***************************:************** ******* ************** *******.*********************.*******:**********************************:***************:*********:***************:********:*:*************************************:**::***************************************************************************************** *:**************************..*******************.*:**********************.*****:**.*.*****::******************:********** *:*****:************:***********: *::**", "identical_positions": 748, "similar_positions": 54, "identity": "92.35%" }, { "cls_id": "homologset.agr.RGD:620999", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61220-1", "uniprot_id": "NELL2_MOUSE", "id": "Q61220-1", "name": "Protein kinase C-binding protein NELL2", "aln": "MHAMESRVLLRTFCVILGLGAVWGLGVDPSLQIDVLTELELGESTDGVRQVPGLHNGTKAFLFQESPRSIKASTATAERFFQKLRNKHEFTILVTLKQIHLNSGVILSIHHLDHRYLELESSGHRNEIRLHYRSGTHRPHTEVFPYILADAKWHKLSLAFSASHLILHIDCNKIYERVVEMPSTDLPLGTTFWLGQRNNAHGYFKGIMQDVHVLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILSKTSAKLSRAEQRMNRLDQCYCERTCTVKGTTYRESESWTDGCKNCTCLNGTIQCETLVCPAPDCPPKSAPAYVDGKCCKECKSTCQFQGRSYFEGERNTVYSSSGMCVLYECKDQTMKLVE-NIGCPPLDCPESHQIALSHSCCKVCKGYDFCSEKHTCMENSVCRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECLTNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSEGFVQCDSRANCINLPGWYHCECRDGYHDNGMFAPGGESCEDIDECGTGRHSCTNDTICFNLDGGYDCRCPHGKNCTGDCVHEGKVKHTGQIWVLENDRCSVCSCQTGFVMCRRMVCDCENPTVDLSCCPECDPRLSSQCLHQNGETVYNSGDTWVQDCRQCRCLQGEVDCWPLACPEVECEFSVLPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHLCCSVDPQCLQEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62918-1", "uniprot_id": "NELL2_RAT", "id": "Q62918-1", "name": "Protein kinase C-binding protein NELL2", "aln": "MHAMESRVLLRTFCVILGLEAVWGLGVDPSLQIDVLSELELGESTAGVRQVPGLHNGTKAFLFQDSPRSIKAPIATAERFFQKLRNKHEFTILVTLKQIHLNSGVILSIHHLDHRYLELESSGHRNEIRLHYRSGTHRPHTEVFPYILADAKWHKLSLAFSASHLILHIDCNKIYERVVEMPSTDLPLGTTFWLGQRNNAHGYFKGIMQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILSKTSAKLSRAEQRMNRLDQCYCERTCTMKGTTYREFESWTDGCKNCTCLNGTIQCETLVCPAPDCPAKSAPAYVDGKCCKECKSTCQFQGRSYFEGERSTVFSASGMCVLYECKDQTMKLVE-NAGCPALDCPESHQIALSHSCCKVCKGYDFCSEKHTCMENSVCRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFLCICQTGYIRIDDYSCTEHDECLTNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSEGFVQCDSRANCINLPGWYHCECRDGYHDNGMFAPGGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCVHDGKVKHNGQIWVLENDRCSVCSCQTGFVMCRRMVCDCENPTVDLSCCPECDPRLSSQCLHQNGETVYNSGDTWVQDCRQCRCLQGEVDCWPLACPEVECEFSVLPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHVCCSVDPQCLQEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99435-1", "uniprot_id": "NELL2_HUMAN", "id": "Q99435-1", "name": "Protein kinase C-binding protein NELL2", "aln": "---MESRVLLRTFCLIFGLGAVWGLGVDPSLQIDVLTELELGESTTGVRQVPGLHNGTKAFLFQDTPRSIKASTATAEQFFQKLRNKHEFTILVTLKQTHLNSGVILSIHHLDHRYLELESSGHRNEVRLHYRSGSHRPHTEVFPYILADDKWHKLSLAISASHLILHIDCNKIYERVVEKPSTDLPLGTTFWLGQRNNAHGYFKGIMQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERTCTMKGTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVE-SSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHICCSVDPQCLQEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1A5Y0-1", "uniprot_id": "NELL2_DANRE", "id": "A1A5Y0-1", "name": "Protein kinase C-binding protein NELL2a", "aln": "------MAFLQLFVGLLCGAAVSAFGVDPAVRIGVFQEFSPGQGFSGVTQVKGFRDDTRAFMFQGSSRSVRVPDAAAGHMLQKLRGKTEFSIALTLKQDKLNSGVILSIHHGEHRLLELESSGQKSEVRLHFRTGLQQTHTEIFPFTLADEQWHRVSVSISAAHLTLYVDCNRIYERVVPVPLMEIPEDSSFWVGQRNSAHGLFKGIMQDLQILVMPQGFITQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSSKLSLAEEKMSGLDSCYCERTCRVKDQIYREEQSWTDGCKNCTCSNGTVRCEKILCPPLDCPDGTTPAYVTGTCCKECQPMCLFSEQTLVEGQSCAVHHPSGLCQLFQCRDRTMHRVPGAEDCPALSCAESDQITLTDRCCRVCRGHDFCAEENICSENSDCVNLDAGASCGCKNGFRPLRLDSAYCEDIDECAEGRHYCRENTECVNTAGSFMCVCHTGFIRIDDYSCTEHDECASGQHDCDENALCFNTVGGHSCSCKPGYSGNGTVCRALCDGRCLNGGSCASPNVCVCVQGFSGQNCETDIDECSEGLVQCAAHATCVNLPGWYHCECRDGYHDNEVFSANGESCRDIDECRTGRSTCANDTVCFNLDGGFDCRCPHGHNCSGDCIHNSRVRHNAQIWVLDTDHCSVCSCQEGQVKCRRMVCDCENPTVDVLCCPECDPRLTSQCLHQNGLLTYSSGDTWIDSCQRCQCLQGEVDCWPLSCPPVDCDFTLVPEGECCPRCVSDPCQAHAVRSDISKTCIDEHGITRFSGSAWVKHGTHCTLCQCKNGHVCCSVDPMCL---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:*: * :: ** .:****:::*.*: *:. *:. ** ** *:::.*:**:** :.**::.. *:* :::****.* **:* :**** :*********** :** *******::.*:***:*:* ::.***:**: *** :**::*:::**:** *::***:****** * ::* .::**:****.*** *******:::********:*****************************:***:*** **::*. **.******* :*. *** :** ******** ***::**.::** *** :: *** *.*****:. * *. :: .**: :*. .**:* *::*:*:**: * .**.*.*.**.**:*:. **:**:*:***:*.: * *** * **: * *.*::***.** *.******************** ****.***:*:*:**:************** :.**:**************.* *****:****.*:*:*.. * ***:* :.***.* ***:* .*********:*:*** ::*.*:***************** :*:..****.***** *** :*:***:*******:*******:**:***:*:.:*:*..*****:.*:******* * * **************: *********:******** *.*****::.*::*:***********.** *:*:*:::**.*******:*****.::*.**:***:** .:.**:**:*:****.**********:****** ** ", "identical_positions": 520, "similar_positions": 201, "identity": "63.41%" }, { "cls_id": "homologset.agr.RGD:621000", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54001-1", "uniprot_id": "P4HA1_RAT", "id": "P54001-1", "name": "Prolyl 4-hydroxylase subunit alpha-1", "aln": "--------------------------------------------------------MIWGVLMMGI----------LLPQCSAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQR--QYFPNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVKH----KSFLTAEDCFELGKVAYTEADYYHTELWMEQALMQLEEGEM---STVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKEKDANKSASGDQSD--QKTTP--KKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVS----------------------KSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60715-1", "uniprot_id": "P4HA1_MOUSE", "id": "Q60715-1", "name": "Prolyl 4-hydroxylase subunit alpha-1", "aln": "--------------------------------------------------------MIWVVLMMAI----------LLPQSLAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQR--QYFPNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQH----KSFLTAEDCFELGKVAYTEADYYHTELWMEQALTQLEEGEL---STVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKEKDANKSASGDQSD--QKTAP--KKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPVTGALETVHYRIS----------------------KSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13674-1", "uniprot_id": "P4HA1_HUMAN", "id": "P13674-1", "name": "Prolyl 4-hydroxylase subunit alpha-1", "aln": "--------------------------------------------------------MIWYILIIGI----------LLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQR--QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKH----KSFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEI---STIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSD--QKTTP--KKKGVAVDYLPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPITGDLETVHYRIS----------------------KSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GVP4-1", "uniprot_id": "A0AC58GVP4_DANRE", "id": "A0AC58GVP4-1", "name": "Prolyl 4-hydroxylase subunit alpha-1", "aln": "MALHSIICLQWMFLQFICAADLSQRTDRPLRSERGTRANRTTLIDFALSTHSRSDSCVWQSVMMGVRSVCCFLLISLLKSSSAHSDFFTSIGHMTDLLFTEKDLVTSLKDYIKAEESKLEQVKQWAEKLDALTATAVQDPEGFLGHPVNAFKLMKRLNTEWGEVEDLVLKDMSDGFISNLTIQR--QYFPNDEDQNGAAKALLRLQDTYKLDTQTISSGDLPGVNTGLPYKSTLTVEDCFELGKIAYSDADYYHTELWMAQALKQLDEGEE---SSVEIATALDYLSYSVYQQGELERALEYTKRLLTVEPEHQRALGNLKYFDYQLAKQKKAEKEQSTKEES--KKEQE--TSDGKK-EYLPEKRKYEKLCRGEGLRMTPRRQKHLFCRYFNGNRHPFYTIGPVKQEDEWDRPRIIRYHEIITEQEIEKIKELSKPRLRRATISNPITGVLETAHYRIS----------------------KSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCGLKETD-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TAB6-1", "uniprot_id": "A0AB32TAB6_DANRE", "id": "A0AB32TAB6-1", "name": "procollagen-proline 4-dioxygenase", "aln": "--------------------------------------------------------MMLAWFLLSF----------LFHFLYAHNDFFTSTGQMTDLLYAEKDLVTSLKEYIKQEENRLEQVKEWADKLDSLTITATQDPEGFLGHPVNAFKLMKRLNSEWSDLENLVLKDTTNGFISNLTVQR--QYFPTDEDQTGAAKALLRLQDTYQLSANAISSGDLPGVVH----KSRMTVEDCYELGKIAYSDADYYHTELWMAQALSQLDEGEE---SPIDKVTVMDYLSYAIYQQGELDRALELTKRMLKLDPNHHRANGNLKYFEFQLEKQRKAENEKKEEDQKRVLDKRD--AQRKRSKDPLPERKKYERLCRGEGIKLTPRRQSRLFCRYSNNNRNPRLLLAPVKQEDEWDRPRIVRYHEIISDSEIETVKEMAKPRLRRATISNPITGVLETAPYRISKRRATVHDPITGKLTTAQYRVSKSAWLSGYEHSTIERINQRIEDVTGLEMDTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFTDVGAAVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCALSEVE-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA69-1", "uniprot_id": "Q9VA69_DROME", "id": "Q9VA69-1", "name": "procollagen-proline 4-dioxygenase", "aln": "--------------------------------------------------------MAADWRLMLLLG------ILLLVGGPANGEVYTALAEMEELLETESVLITNLEGYIRVQEDKLNFLKNKMDEYQREHSDASHDITAYVSNPINAYLLTKRLTTDWRQVENLMEHDVGTDFLQNITQYRSLLKFPSDEDLNGAAVALLRLQDTYQLDTSSVARGKLNGIQY----STEMSSDDCFELGRQSYVNHDYYHTVLWMNEAMARMLEEPTNHTQSFTKADILEYLAFSTYKEGNIESALTMTNELLQLLPHHERANGNKRFYEKEIAQQLQLRKMKGDDGTDEMPKSDLPVAKSDPAIFDMTERRAYEMLCRGE-LKPSPSDLRSLRCRYVT-NRVPFLRLGPLKLEEVHADPYIVIYHDAMYDSEIDLIKRMARPRFRRATVQNSVTGALETANYRIS----------------------KSAWLKTQEDRVIETVVQRTADMTGLDMDSAEELQVVNYGIGGHYEPHFDFARKEEQRAFEGLNLGNRIATVLFYMSDVEQGGATVFTSLHTALFPKKGTAAFWMNLHRDGQGDVRTRHAACPVLTGTKWVSNKWIHERGQEFRRPCDLEEDHGEFAI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . *: *: .:*: ..* :*: *. *:*.*: **: :*.:*: :*: :: : * :* .::.:*:**: * ***.::* ::*:*: :* .*:.*:* * **.*** *** **:******:*.:.::: *.* *: .: :: :**:***: :* : ***** *** :*: :: * ... . ::**::: *::*::: ** *:.:* : *.*.** ** ::: : :: . .: . . . . :.*:: ** ***** :: :* * *** ** * :.* * *: * *: :*: : : **: :* :::**: ***: :. ** * *. **:* ***** *. .:. : * *:***::.:******.***:**:*******.**:* **. *. ****** ******* ******..: ::: * ****.** **. .*:** *********.*.*******:*********** *.* . ", "identical_positions": 214, "similar_positions": 161, "identity": "33.44%" }, { "cls_id": "homologset.agr.RGD:621001", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32214-1", "uniprot_id": "CALCR_RAT", "id": "P32214-1", "name": "Calcitonin receptor", "aln": "-----------------------------------------MRFLLLNRFTLLLLLLVSPTPVLQAPTNLTDSGLDQEPFLYLVGRKKLLDAQYKCYDRIQQLPPYEGEGP-------YCNRTWDGWMCWDDTPAGVMSYQHCPDYFPDFDPTEKVSKYCDENGEWFRHPDSNRTWSNYTLCNAFTPDKLHNAYVLYYLALVGHSMSIAALIASMGIFLFFKNLSCQRVTLHKNMFLTYILNSIIIIIHLVEVVPNGDLVRRDPMHIFHHNTYMWTMQWELSPPLPLSAHEGKMDPHDSEVISCKILHFFHQYMMACNYFWMLCEGIYLHTLIVMAVFTEDQRLRWYYLLGWGFPIVPTIIHAITR----AVYYNDNCWLSTETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRQTHEAEA-----YMYLKAVKATMVLVPLLGIQFVVFPWRPS-NKVLGKIYDYLMHSLIHFQGFFVATIYCFCNHEVQVTLKRQWAQFKIQWS-------------HRWGRRRRPTNRV----VSAPRAVAFAEPGGLPIYICHQEPRNPPVSNNEGEEG-----------------------------------------------------TEMIPMNVIQQDSSA----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60755-1", "uniprot_id": "CALCR_MOUSE", "id": "Q60755-1", "name": "Calcitonin receptor", "aln": "------------------------MTPRRSRVKRRNLRKPKMRFLLVNRFTLLLLLLVSPTPVLQAPTNLTDSGLDQEPFLYLVGRKKLLDAQYKCYDRIHQLPSYEGEGL-------YCNRTWDGWMCWDDTPAGATAYQHCPDYFPDFDTAEKVSKYCDENGEWFRHPDSNRTWSNYTLCNAFTSEKLQNAYVLYYLALVGHSLSIAALVASMLIFWIFKNLSCQRVTLHKHMFLTYILNSIIIIIHLVEVVPNGDLVRRDPMHIFHHNTHMWTMQWELSPPLPLSAHEGKMDPHASEVISCKVLHFLHQYMMSCNYFWMLCEGIYLHTLIVMAVFTDEQRLRWYYLLGWGFPIVPTIIHAITR----ALYYNDNCWLSAETHLLYIIHGPVMVALVVNFFFLLNIVRVLVTKMRQTHEAES-----YMYLKAVKATMVLVPLLGIQFVVFPWRPS-NKVLGKIYDYLMHSLIHFQGFFVATIYCFCNHEVQVTLKRQWTQFKIQWS-------------QRWGRRRRPTNRV----VSAPRAVAFAEPDGLPIYICHQEPRNPPISNNEGEES-----------------------------------------------------TEMIPMNVIQQDASA----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30988-2", "uniprot_id": "CALCR_HUMAN", "id": "P30988-2", "name": "Calcitonin receptor", "aln": "-----------------------------------------MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQQLPAYQGEGP-------YCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDP-------------------------------------VSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITR----AVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAES-----HMYLKAVKATMILVPLLGIQFVVFPWRPS-NKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWN-------------QRWGRR--PSNR------SARAAAAAAEAGDIPIYICHQELRNEP-ANNQGEES-----------------------------------------------------AEIIPLNIIEQESSA----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KF12-1", "uniprot_id": "A0A0B4KF12_DROME", "id": "A0A0B4KF12-1", "name": "", "aln": "----------------------------------------MSDQIGNPNATFSGSGSGSGTNVASIAESVAESGPDFDALRAACETRLNASGQLAGSG-----GPGAEAGT-------HCAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPARYAHKECGLDGEWFKHPLTNKTWSNYTTC--VNLEDLNWRHTVNLISEVGYGTSLLAILLSLAILGYFKSLKCARITLHMNLFASFAANNSLWLVWYLLVMPNSELLHQSP-------------------------------------MRCVALHITLHYFLLSNYSWMLCEGFYLHTVLVAAFISEKRLVKWLIAFGWGSPAIVIFVYSMARGLGGTPEDNRHCWMN-QTNYQNILMVPVCISMFLNLLFLCNIVRVVLLKLNAPASIQGSCGPSRTVLQAFRATLLLVPLLGLQYILTPFRPAPKHPWENTYEIISAFTASFQGLCVAILFCFCNGEVIAQMKRKWRMMCFSNRPRTNSYTATQVSFVRCGPPLPGEEKVXLKDMSAKRRASAGPQHHQPHHQSHQLSTDQQRARSQSLASSSSFLEGWRDRMPFLKRRQTIDHSRQSQPLMEEGGETVGQAKSAPGAVDRPTLMTTIAEDVAETGTAATSHAASTSDAAAAAAVGAGGATGAEEGHPNGMGTVIVRMERAGQQHMADEAL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VYH9-1", "uniprot_id": "Q9VYH9_DROME", "id": "Q9VYH9-1", "name": "", "aln": "MATTSSDSESQNVDVASQAQTQDNLRIFLKHLYAECVFRYQNVTYDTDDPSFSLGPATDYDSDLPENFSPVPRYLENAAMNEGVIDMRNVDEELAEKEELMATVVSATMATNQKENRLFCPLNFDGYLCWPRTPAGTVLSQYCPDFVEGFNRKFLAHKTCLENGSWYRHPVSNQTWSNYTNC--VDYEDLEFRQFINELYVKGYALSLLALLISIIIFLGFKSLRCTRIRIHVHLFASLACTCVAWILWYRLVVERSETIAENP-------------------------------------LWCIGLHLVVHYFMLVNYFWMFCEGLHLHLVLVVVFVKDTIVMRWFIVISWFSPIPIAIVYGLAR--HFSSPDNKHCWIT-DSLYLWIFSVPITLSLLASFIFLINVLRVIVRKLHPQSAQPAP----LAIRKAVRATIILVPLFGLQHFLLPYRPDAGTQLDHFYQMLSVVLVSLQGFVVSFLFCFANHDVTFAIR------------------------------------------TLLNKLLPSLVTPPPAGSNTGQMATTTPSRELGV--------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : .: . : . .* .:**::** *..*. : ***:. .*: . * * .* *::** .*:****** * . :.*. : : *:. *: ::: *: *: *:.* * *: :* ::* : . :: *: ..: : ..* : * **: :*:: ** **:***::** ::* ....: ::* :.* * ::.::* : * :**:. :: *: *: ::. .::** *::**:: *:. . :*.:**::****:*:*..: *:** : *: : :**: *: ::**.* :* :: : . * :.. . ", "identical_positions": 88, "similar_positions": 132, "identity": "12.64%" }, { "cls_id": "homologset.agr.RGD:621002", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0S9-1", "uniprot_id": "PRAF1_MOUSE", "id": "Q9Z0S9-1", "name": "Prenylated Rab acceptor protein 1", "aln": "-------MAAQKDQQKDAEGEGLSATTLLPKLIPSGAGREWLERRRATIRPWGTFVDQQRFSRPRNVGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLQSKLVLFGREVSPAHQYALAGGVSFPFFWLAGAGSAVFWVLGATLVLIGSHAAFHQMEPADGEE---LQMEPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35394-1", "uniprot_id": "PRAF1_RAT", "id": "O35394-1", "name": "Prenylated Rab acceptor protein 1", "aln": "-------MAAQKDQQKDAEVEGLSATTLLPKLIPSGAGREWLERRRATIRPWGTFVDQQRFSRPRNVGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLQSKLVLFGREVSPAHQYALAGGVSFPFFWLAGAGSAVFWVLGATLVLIGSHAAFHQIEPADGEE---LQMEPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UI14-1", "uniprot_id": "PRAF1_HUMAN", "id": "Q9UI14-1", "name": "Prenylated Rab acceptor protein 1", "aln": "-------MAAQKDQQKDAEAEGLSGTTLLPKLIPSGAGREWLERRRATIRPWSTFVDQQRFSRPRNLGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLESKLVLFGREVSPAHQYALAGGISFPFFWLAGAGSAVFWVLGATLVVIGSHAAFHQIEAVDGEE---LQMEPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z823-1", "uniprot_id": "A1Z823_DROME", "id": "A1Z823-1", "name": "PRA1 family protein", "aln": "MAHTGGNLSGNMQPPPPSGGRFSVDMQSLPSLSNLPSPLQIFQMVRNSLRPWVVFFNINNFKTAISMQRLNSRVIRNLSYFQANYVFIFFVLMIYCLITAPCILLVILASAFGCHKLRVR--NSNITIVGQQLTPSQQIIALNLATAPVLFLVGAGAVLFWTLGASCFVIAMHAIFYNIDAIVTEENEGFLAQVV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53633-1", "uniprot_id": "PRA1_YEAST", "id": "P53633-1", "name": "Prenylated Rab acceptor 1", "aln": "-------------MNQLGALAQVSRFTQNFSMENIKSEFQSLQSKLATLRTPQEFFNFKKISKPQNFGEVQSRVAYNLKYFSSNYGLIIGCLSIYTLLTNLLLLFVIVLVVAGIVGINKLKGEELVTPFG-SFKTNQLYTGLVCVAVPIGFLASPISTLLWLIGASAVSVFGHASLMEKPIETVFD-----EETV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: : : :: ::*. *.: :.:. . .. .: .*: *:.*:.:** ::: * :* ::* :*..: . : :. :. .* .... : : *. :*... :.::* :**: . : ** : : : : *", "identical_positions": 20, "similar_positions": 68, "identity": "10.26%" }, { "cls_id": "homologset.agr.RGD:621003", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35260-1", "uniprot_id": "NACC1_RAT", "id": "O35260-1", "name": "Nucleus accumbens-associated protein 1", "aln": "MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNSSR----SAVVELPAAVQPQSFQQILTFCYTGRLSMNMGDQFLLIYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHPEEAPSSEPQSPVAQILG-----------------WPACSTPLPLVSRVKTEQ-ELD--SVQCTPMAKRLWDSSQKEAG---GSGGNNGSRKMAKFSTPDLAPNRMPQPVS------VATATAAVA---------VVAVGGCVSGPSMSERTSPGTSSAYTSDSPSSYHNEEDEEEDAGEEGTDEQYRQICNMYTMYSMLNVGQTV-EKVEALPEQVVLESHSRIRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWLPKTKPLHLVEGDNYSSFISDTGKIEPDMMSMEHSFETASHDG-----EAGPSAEVLQ-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSZ8-1", "uniprot_id": "NACC1_MOUSE", "id": "Q7TSZ8-1", "name": "Nucleus accumbens-associated protein 1", "aln": "MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNSSR----SAVVELPAAVQPQSFQQILTFCYTGRLSMNMGDQFLLIYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHPEEAPSSEPQSPVAQTLG-----------------WPACSTPLPLVSRVKTEQ-ELD--SVQCTPMAKRLWDSSQKEAG---GSGGNNGSRKMAKFSTPDLALNRMPQPLS------MATATAAVA---------VVAVGGCVSGPSMSERTSPGTSSAYTSDSPSSYHNEEDEEEDAGEEGTDEQYRQICNMYTMYSMLNVGQTA-EKVEALPEQVVLESRSRIRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWLPKTKPLHLVEGDNYSSFISDTCKIEPDMMSMEHSFETASHDG-----EAGPSAEVLQ-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RE7-1", "uniprot_id": "NACC1_HUMAN", "id": "Q96RE7-1", "name": "Nucleus accumbens-associated protein 1", "aln": "MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNNSR----SAVVELPAAVQPQSFQQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHAEEAPSSEPQSPVAQTSG-----------------WPACSTPLPLVSRVKTEQQESD--SVQCMPVAKRLWDSGQKEAG---GGG--NGSRKMAKFSTPDLAANRPHQPPPPQQAPVVAAAQPAVAAGAGQPAGGVAAAGGVVSGPSTSERTSPGTSSAYTSDSPGSYHNEEDEEEDGGEEGMDEQYRQICNMYTMYSMMNVGQTA-EKVEALPEQVAPESRNRIRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWMPKVKVLK-AEDDAYTTFISETGKIEPDMMGVEHGFETASHEG-----EAGPSAEALQ-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YZ89-1", "uniprot_id": "A0A8M6YZ89_DANRE", "id": "A0A8M6YZ89-1", "name": "", "aln": "MAQTLQMAIPNFGNNVLECLNEQRLQGLYCDVSVVVKGHTFKAHRAVLAASSSYFRDLFNSSAGSKTPTVVELPPAVQPQSFQQILAFCYTGRLSMNVGDQFLLMYTAGFLQIQQIMEKGTEFFLKVSSPSCDSQGLHTEETPPSEPQSPVTQTAAGAAANGGAGVVATAASRPASCLTPLPLVSRVKTEQPETSPYSVVCTPVAKRLWEGSNREGSGGLGAAGGGGMRKAARFSQEMARGSAIQQQGS------MGGLGMGLGMGTGGHGAGSGSTNGNGTSSATPEGTSPGTLSAYASDSPISYHDDE-EEEEAVDDGTEEQYRQICNMYTMYSMLNVGATAGERVEALPDHS--ETRPRMRGRQDLASLPAELIAQIGNRCHPKLYEEGDPAEKLELVSGTSVYISRAQLMNCHVSAGTRHKVLLRRLLAAFFDRSTLANSCGTGIRSSTNDPSRKPLDSRVLHAVKFYCQNFATSFKESEMNAIAADMCTNARRVVRKSWIPKLKLLM-AEGDAYASFLPDSNKMEADGLSGEPTFETASLEGGASVETGGSSGESLQGVGGDNGTLFQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* ******.:***********************:********************.* .:*****.***********:**********:******:*********:***********************.**:*.*******:* . .:* ************* * . ** * *:*****:..::*.. *.. .* ** *:** . * . :. .:. :..* :..: .* ***** ***:**** ***::* ***:. ::* :***************:*** *. *:*****:: *:: *:* ************ ***********:****:******:**.***:************************:****.***************** *************:******..*************************:** * * .*.* *::*:.:: *:*.* :. * ***** :* .*.*.* ** ", "identical_positions": 365, "similar_positions": 89, "identity": "63.7%" }, { "cls_id": "homologset.agr.RGD:621004", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A3KGF7-1", "uniprot_id": "PLCB2_MOUSE", "id": "A3KGF7-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "aln": "---MSLLNPVLLPP--NVKAYLSQGERFIKWDDETSIASPVILRVDPKGYYLYWTYQNQEMEFLDVTSIRDTRFG--KFAKIPKSQKLREVFNMDFPDNHFLLKTLTVVS-GPDMVDLT-----FYNFVSYKENVGKDWAEDVLALAKHPMTVN---APRSTFLDKILVK--------------------LKMQLNPEGKIPVKNFFQMFP---ADRKRVEAALGACHLA-----------KGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHSKAKP---YMTKEHLTKFINQKQRDPRLNSLLFPPARPEQVQVLIDKYEPSGINVQRGQLSPEGMVWFLCGPENS---VLAHDTLLIHQD------------MTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDILFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKMAEYCRSMFGETLLTDPLENFPLKPGIPLPSPEDLRGKILIKNKK--------------NQFSGPAS---------------------PSKKPGGVAEGSLPSSVPVEEDTGWTAEDRTEVEE---EEVVEEEEEEESGNLDEEEIKKMQSDEGTAG--------------LEVTAYEEMSSLVNYIQPTKFISFEFSAQKNRSYVVSSFTELKAYELLSK-ASMQFVDYNKRQMSRVYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMRRLDKQFNPFSVDRIDVVVATTLSITIISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKLSPTANSINPVWKEEPFIFEKILMPELASLRIAVMEEGSKFLGHRIIPINALHSGYHHLCLRSESNMALTMPALFVFLEMKDYIPDTWADLTVALANPIKYFNAQDKKSVKLKGVT----------------------GSLPEKLFS-GTPVASQSNGAPVSAGNGSTAPGTKATG---------------------------------EEATKEVTEPQTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELQTQAAG----CKLRPGK-------GSRKKRTLPC------EETV-VAPSEPHDRADPRVQELKDRLEQELQQQGEEQYRSVLKRKEQHVTEQIAKMMELAREK-QAAELKTFKETSETDTKEMKKKLEAKRLERIQAMTKVTTDKVAQERLKREINNSHIQEVVQAVKQMTETLERHQEKLEERQ----TACLEQIQAMEKQFQEKALAEYEAKMKGLEAEVKESVRAYFKDCFPTEAEDK------PERSCEASEESCPQEPLVSKADTQESRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O89040-1", "uniprot_id": "PLCB2_RAT", "id": "O89040-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "aln": "---MSLLNPVLLPP--KVKAYLSQGERFIKWDDETSIASPVILRVDPKGYYLYWTHQSKEMEFLDVTSIRDTRFG--KFAKIPKSQKLREVFNMDFPDNHFLLKTFTVVS-GPDMVGLT-----FHNFVSYKENVGKDWAEDVLALAKHPMTAN---ASRSTFLDKILVK--------------------LKMQLSPEGKIPVKNFFQMFP---ADRKRVEAALSACHLA-----------KGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHAKAKP---YMTKEHLTKFINQKQRDPRLNSLLFPPARPEQVQALIDKYEPSGINVQRGQLSPEGMVWFLCGPENS---VLAHDTLRIHQD------------MTQPLNHYFINSSHNTYLTAGQFSGPSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDILFKEAVEAIAESAFKTSPYPVILSFENHVDSPRQQAKMAEYCRTMFGETLLTEPLENFPLKPGMPLPSPEDLRGKILIKNKK--------------NQFSGPAS---------------------PNKKPDGVSEGGFPSSVPVEEDTGWTAEDRTEVEEGEEEEEVEEEEEEESGNLDEEEIKKMQSDEGTAG--------------LEVTAYEEMSSLVNYIQPTKFISFEFSAQKNRSYLVSSFTELKAYELLSK-ASMQFVDYNKRQMSRVYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMRRQDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKLSPTANSINPVWKEEPFIFEKILVPELASLRIAVMEEGGKFIGHRIIPINALHSGYHHLCLRSESNMPLTMPALFVFLEMKDYVPDTWADLTVALANPIKYFSAHDKKSVKLKEVT----------------------GSLPEKLFS-GIPVASQSNGAPVSAGNGSTAPGTKAK----------------------------------EEATKEVAEPQTTSLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELQDPAAS----CKLRPGK-------GSRKKRIVPC------EETI-VVPREVLEGPDPRVQDLKDRLEQELQQQGEEQYRSVLKRKEQHVTEQIAKMMELAREK-QAAELKSFKETSETDTKEMKKKLEAKRLERIQAMTKVTTDKVAQERLKREINNSHIQEVVQAVKQMTETLERHQEKLEEKQ----TACLEQIQAMEKQFQEKALAEYEAKMKGLEAEVKESMRACFKACFPTEAEEK------PERPCEASEESCPQEPLVNKTDTQESRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00722-1", "uniprot_id": "PLCB2_HUMAN", "id": "Q00722-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "aln": "---MSLLNPVLLPP--KVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKEMEFLDITSIRDTRFG--KFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVS-GPDMVDLT-----FHNFVSYKENVGKAWAEDVLALVKHPLTAN---ASRSTFLDKILVK--------------------LKMQLNSEGKIPVKNFFQMFP---ADRKRVEAALSACHLP-----------KGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKP---YMTKEHLTKFINQKQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWFLCGPENS---VLAQDKLLLHHD------------MTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKK--------------NQFSGPTS---------------------SSKDTGGEAEGSSPPSAPAGEGTVWAGEEGTELEE----EEVEEEEEEESGNLDEEEIKKMQSDEGTAG--------------LEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSK-ASVQFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHLCLHSESNMPLTMPALFIFLEMKDYIPGAWADLTVALANPIKFFSAHDTKSVKLKEAM----------------------GGLPEKPFPLASPVASQVNGALAPTSNGSPAARAGAR----------------------------------EEAMKEAAEPRTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELGPPGVGGVGACKLGPGK-------GSRKKRSLPR------EESAGAAPGEGPEGVDGRVRELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREK-QAAELKALKETSENDTKEMKKKLETKRLERIQGMTKVTTDKMAQERLKREINNSHIQEVVQVIKQMTENLERHQEKLEEKQ----AACLEQIREMEKQFQKEALAEYEARMKGLEAEVKESVRACLRTCFPSEAKDK------PERACECPPELCEQDPLIAKADAQESRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25455-3", "uniprot_id": "PIP1_DROME", "id": "P25455-3", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II", "aln": "--MMSAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTG--QYAKRPKDNKLRQIVTLG-PQDTLEEKTVTVCH-GSDFVNMT-----FVNFCCTRRDIAQLWTDGLIKLAYSLAQLN---GSAIMFLQKAHTK--------------------LCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKALDVTGLP-----------SGKVDSISVSKFQFEDFYNLYKYLTQRSEVERLFDSIVGNSKRK--CMSIAQLVEFLNKTQRDPRLNEILYPYANPARAKELIQQYEPNKFNAQKGQLSLDGFLRYLMGDDNP---IMAPSKLDLCDD------------MDQPMSHYFINSSHNTYLTGHQLTGKSSVEIYRQCLLAGCRCVELDFWNGR--TEEPVIVHGYTFVPEIFAKDVLEAIAESAFKTSEYPVILSFENHCN-PRQQAKIANYCREIFGDMLLDKPLDSHPLEPNMDLPPPAMLRRKIIIKNKKKHHHHHHHHHHKKPAQVGTPAANNKLTTANSVDAKAAQQVGLSASHEDGGVTRSTANGDVATGTGTGSAAGTAGHAPP---LQQIRQSSKDSTGSSDSDSSSEDESLPNTTPNLPSGNEPPPEKAQKETEAGAEISALVNYVQPIHFSSFENAEKKNRCYEMSSFDEKQATTLLKE-RPIEFVNYNKHQLSRVYPAGTRFDSSNFMPQLFWNAGCQLVALNFQTLDLAMQLNLGIFEYNARSGYLLKPEFMRRSDRRLDPFAESTVDGIIAGTVSITVLSGQFLTDKRANTFVEVDMYGLPADTVRKKFRTKTVRDNGMNPLYDEEPFVFKKVVLPELASIRIAAYEEGGKLIGHRVLPVIGLCPGYRHVNLRSEVGQPIALASLFLCVVVKDYVPDDLSNFAEALANPIKYQSELEKRDIQLSVLTDEAEALGSADEDLSKSFVFVQVGGQKKELRPVESLATSPKHRPSISAAAAMSVDVTVDRTDGGRGEDSISIVAPSIQHQHSLDQSVSTSIRQVESSQFDVDLVLAEPLEKILDHKSVKEKRLEMEKKLESLRKKHDKEKIKIAGQKSSPLEGKKPKFAITNKLVKRLSNKSLNCLSPHSEPGVEIPACPLDLGDSSEESAAADAGEDLAGGSSSLDGRTQESRLRSACREYTSQYRELQEKYHEAIYSAAEKVLKTSQTGQTKQLKASLDKVTGEVMHQLQEARRNEVKNLATVHRDRDELIRMKREVASSVVERGVAERVRLKQTFDRRTDELQKQHDSVRNALAEHRSKARQILDKEAESRSCVSSNGFLVLFHGPHHHGCTGSGSSALSGNNLTLNLDAGAAGSHSAISPAKSHNSIAAAAEMKT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32383-1", "uniprot_id": "PLC1_YEAST", "id": "P32383-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1", "aln": "MTESAIDDQRFNLTKELQRHSCRDQGKITQKDDALDFISYSSFQSSFNTDQKSANNGSTVRRSIRSIFRRAAELPRVHMGPLTYSHGINELVNKKLRKDCDLSTLCRVLQRGIRMIRMTRRRRKFYEFKLINNNGQIIWKDGSKYLELDSVKDIRIGDTASTYQEEVDPKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFNTFLSCICGLVKLRRELMESILLPDNSQFARIHWQITVSEKEEDEKKDTLSFADVKKLCDKFHIYVSTGQLLEFFQLADINHNGLLNYFEFEKFIKILKNRKEVNMIWSKFTKPPHSHLSFENFFQFLITEQHEQVDRQTAWSYFIKYREPTQLTMGQDGFTKFLKEQPYLVEVKEELYSKPLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDIWDGE---NGPVVCHGF-LTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLIMREVLAEQLYFVG-------TRTDKLPSPRELKHKILLKSKK--------------------------------------------------TSEATRGLSVNEPFPSSFSSSYESANEQ---ELRMKDDSTNSSSATNSSSMQRIKRIG-----------------LKKHADIINDVSNISGIHGIKFRNFSLPESKTIAHCFSLNERKVEYMIKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNWQTNDIGQQLNLAMFQILDHQ-----------PDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFENGSDPVTVKIRILS--------TQLLPRLNDTSPSRNNTNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKSSQGNGFNPIWD-AEVSITLKDTDLTFIKFMVISEETQIASVCLKLN-----YLRMGYRHIPLFNME-------------------------GEQYIFCTLFIHTQIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . : :: : ** : :: . : . : * .. : . . .: :.::.. .: . * * :: :* * :* ..: * :. * . : :: * ::: ..: .:.::. : *:.: :: . . * : . . : .: : . .:: :. .: :*:: :. .:* : :.* : : :::: :. *: *:. : :: :. :. . : . :*:.**** ******* . *:: .*.* * * * ******:* *.*. : *:: **: :.. * * .:..* : ** ** **:*:*:* : : .*: . : : : **.* *: **::*.** :.. .. : :. :.:.. :.:. :... .. : : : : :. :: :* .*. . .*. .: .* . : .: :.: .:*:: : *:** * .***: * **:** *:** *:** *: * *:.:*: :. * :.. . ::. . . .::. : . * *.: *. *. .* .: ..: . .: . ::* :: . . . . *:. : :* . .: . * . : :.. * : : * :: : ", "identical_positions": 109, "similar_positions": 269, "identity": "7.86%" }, { "cls_id": "homologset.agr.RGD:621005", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64704-1", "uniprot_id": "STX3_MOUSE", "id": "Q64704-1", "name": "Syntaxin-3", "aln": "----MKDRLEQLKAKQLTQDDDTDEVEIAID-NTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDE--VRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGN-PAIFTSG-IIDSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKRAMKYQGQARKKLIIIIVVVVVLLGILALIIGLSVGLK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08849-1", "uniprot_id": "STX3_RAT", "id": "Q08849-1", "name": "Syntaxin-3", "aln": "----MKDRLEQLKAKQLTQDDDTDEVEIAID-NTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDE--VRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGN-PAIFTSG-IIDSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKRAMKYQGQARKKLIIIIVIVVVLLGILALIIGLSVGLK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13277-1", "uniprot_id": "STX3_HUMAN", "id": "Q13277-1", "name": "Syntaxin-3", "aln": "----MKDRLEQLKAKQLTQDDDTDAVEIAID-NTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDE--VRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGN-PAIFTSG-IIDSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVGLN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24547-1", "uniprot_id": "STX1A_DROME", "id": "Q24547-1", "name": "Syntaxin-1A", "aln": "---MTKDRLAALHAAQ-SDDEEETEVAVNVDGHDSYMDDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSAPQTDEKTKQELEDLMADIKKNANRVRGKLKGIEQNIEQEEQQNKSSADLRIRKTQHSTLSRKFVEVMTEYNRTQTDYRERCKGRIQRQLEITGRPTNDDELEKMLEEGN-SSVFTQGIIMETQQA--KQTLADIEARHQDIMKLETSIKELHDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARRK-KIMILICLTVLGILAASYVSSYFM----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39926-1", "uniprot_id": "SSO2_YEAST", "id": "P39926-1", "name": "Protein SSO2", "aln": "MSNANPYENNNPYAENYEMQEDLNNAPTGHSDGSDDFVAFMNKINSINANLSRYENIINQIDAQHKDLLTQVSEEQ--EMELRRSLDDYISQATDLQYQLKADIKDAQRDG------LHDSNKQAQAENCRQKFLKLIQDYRIIDSNYKEESKEQAKRQYTIIQPEATDEEVEAAINDVNGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKTMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQQDVEQGVGHTNKAVKSARKARKNKIRCLIICFIIFAIVVVVVVVPSVVETRK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32867-1", "uniprot_id": "SSO1_YEAST", "id": "P32867-1", "name": "Protein SSO1", "aln": "MSYNNPYQLETPFEESYELDE--GSSAIG-AEG-HDFVGFMNKISQINRDLDKYDHTINQVDSLHKRLLTEVNEEQ--ASHLRHSLDNFVAQATDLQFKLKNEIKSAQRDG------IHDTNKQAQAENSRQRFLKLIQDYRIVDSNYKEENKEQAKRQYMIIQPEATEDEVEAAISDVGGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKSMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQLDVEQGVGHTDKAVKSARKARKNKIRCWLIVFAIIVVVVVVVVVPAVVKTR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :: : *: ::.. . :.: .. ::: . :. :*: : .*. : .*. :: :** : :.: . :::* . ::*:::: .*. : :::*. * : :** * :.::*:* :.. . :*:.. : .: . * :*::::.**:::::**.:: ** ::* *: ** .* * :* *: :* .: *: . .*.:*:* :**:: :: . :: ::. . : ", "identical_positions": 40, "similar_positions": 116, "identity": "13.2%" }, { "cls_id": "homologset.agr.RGD:621007", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88797-1", "uniprot_id": "DAB2_RAT", "id": "O88797-1", "name": "Disabled homolog 2", "aln": "MSNEVETSTTNGQPDQQAAPKAPSKKEKKKG--------------SEKTDEYLLARFKGDGVKYKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEEKKKVEEANKAEENGSEALMTLDDQANKLKLGVDQMDLFGDMSTPPDLNNPTESRDILLVDLNSEIDTNQNSLRENPFLTNGVTSCSLPRPKPQASFLPESAFSANLNFFPTPNPDPFRDDPFAQPDQSAPSSFHSLTSADQKKANPGSLSTPQSKGPLNGDTDYFGQQFD-QISNRTGKQEAQGGPWPYPSSQTQQAVRTQNGVSEKEQNG---FHIKSSPNPFVGSPPKGLSVPNGVKQDLESSVQSSAHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFA---SEPPGQMSPTGQPAVPQANFMDLFKTSAPAPMGSGPLVGLGTVPVTPPQAGPWT--PVVFTPSTTVVPGAIISGQPSGFGQPLVFGTTPAVQVWNQ-PSSFATAASPPPPAVW--CPTTSVAPNTWSSTSPLGNPFQSSNIFPPSTISTQSFPQPMMSSVLVTPPQPPPRNGPLKDTLSDAFTGLDPLGDKEVKEVKEMFKDFQLRQPPLVPSRKGETPSSGTSSAFSSYFNNKVGIPQEHVDHDDFDANQLLNKINEPPKPAPRQG---------------------------------VLSGTKSADNSLENPFSKG-FSSTNPSVVS---QPASS-DAHRSPFG-NPFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98078-1", "uniprot_id": "DAB2_MOUSE", "id": "P98078-1", "name": "Disabled homolog 2", "aln": "MSNEVETSTTNGQPDQQAAPKAPSKKEKKKG--------------SEKTDEYLLARFKGDGVKYKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEDKKKVEEANKAEENGSEALMTLDDQANKLKLGVDQMDLFGDMSTPPDLNSPTESKDILLVDLNSEIDTNQNSLRENPFLTNGVTSCSLPRPKPQASFLPENAFSANLNFFPTPNPDPFRDDPFAQPDQSAPSSFDSLTSPDQKKASLSSSSTPQSKGPLNGDTDYFGQQFD-QLSNRTGKPEAQGGPWPYPSSQTQQAVRTQNGVSEREQNG---FHIKSSPNPFVGSPPKGLSVPNGVKQDLESSVQSSAHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFA---SEPPGQMSPTGQPAVPQSNFLDLFKGNAPAPVG--PLVGLGTVPVTPPQAGPWT--PVVYSPSTTVVPGAIISGQPPSFRQPLVFGTTPAVQVWNQ-SPSFATPASPPPPTVW--CPTTSVAPNAWSSTSPLGNPFQSNNIFPPPTMSTQSSPQPMMSSVLATPPQPPPRNGPLKDIPSDAFTGLDPLGDKEVKEVKEMFKDFQLRQPPLVPSRKGETPPSGTSSAFSSYFNNKVGIPQEHVDHDDFDANQLLNKINEPPKPAPRQG---------------------------------VLLGTKSADNSLENPFSKG-FSSSNPSVVS---QPASS-DPHRSPFG-NPFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P98082-1", "uniprot_id": "DAB2_HUMAN", "id": "P98082-1", "name": "Disabled homolog 2", "aln": "MSNEVETSATNGQPDQQAAPKAPSKKEKKKG--------------PEKTDEYLLARFKGDGVKYKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEEKKKIEEASKAVENGSEALMILDDQTNKLKSGVDQMDLFGDMSTPPDLNSPTESKDILLVDLNSEIDTNQNSLRENPFLTNGITSCSLPRPTPQASFLPENAFSANLNFFPTPNPDPFRDDPFTQPDQSTPSSFDSLKSPDQKKENSSSSSTPLSNGPLNGDVDYFGQQFD-QISNRTGKQEAQAGPWPFSSSQTQPAVRTQNGVSEREQNG---FSVKSSPNPFVGSPPKGLSIQNGVKQDLESSVQSSPHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFAPPVSEPSGQASPTGQPTALQPNPLDLFKTSAPAPVG--PLVGLGGVTVTLPQAGPWNTASLVFNQSPSMAPGAMMGGQPSGFSQPVIFGTSPAVSGWNQ-PSPFAASTPPPVPVVW--GPSASVAPNAWSTTSPLGNPFQS-NIFPAPAVSTQ--PPSMHSSLLVTPPQPPPRAGPPKDISSDAFTALDPLGDKEIKDVKEMFKDFQLRQPPAVPARKGEQTSSGTLSAFASYFNSKVGIPQENADHDDFDANQLLNKINEPPKPAPRQV---------------------------------SLPVTKSTDNAFENPFFKDSFGSSQASVASS--QPVSS-EMYRDPFG-NPFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P909-1", "uniprot_id": "A0A8M9P909_DANRE", "id": "A0A8M9P909-1", "name": "", "aln": "MSAEVETSTP---PVEQPPFKTPSKKEKKKAAAS-----------PEKTDEFLLARFKGNGVRYKAKLIGVDDVPEARGDKMSQDSMMKLKGKAVAARSQGKHKQRVWVNISLSGITVTDEKTGAAILEHAVNKISFIARDVTDSRAFGYVCGAEGQHQFFAIKTAQQAEPLVIDLKDLFQLIFNMKKKEVEGSKKDENNKVVENGS-------EGSHNDRKGVEQLDLFGDMSTPPDLNSPS-SEDILLMDLSTEIDSNQNCVKGNPFTSSCVS-------RAQSSLTPENPFTSQLSFFPTPIHDPFSDDPFYKKSDDQ--------SIRDDPAN-HSPNSLFNGGPKNGDSDYLGQQFD-QLSNRTVIQALSNGQWPVDGRAGETTNWTQNTVPVQEQNG---HGN-GMPNPFVEKMQNGVKHENG---GTEESHVHQAKDSVIICPPPLNMKAGRGRRSVKSPSNENLGMASFV------SAEQSESPPPPPESCSVSSLFSRSPSSTDT---LTDLEGLSLQAPSG-----------SSLWNQPLASIFSVSQPFTQAPVFSSSPGSVWANA-PAGFGSSTVSQQLPSWSAAPVSNGSNGSWSPHPTLGNPFQS-SVFPDGQQSSS--PPPLVPPRPVATKEAP-------KVDSNAFVDLDPLGEKEKRDIKDMFKDFQMAKPPNVPARK------------------------------------------EPLKIG--------------------------------------------GQNPFDNSYGKDPFGTSVPATSAPPIKAVGL-DSFRDPFG-NPFA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P9G4-1", "uniprot_id": "A0A8M1P9G4_DANRE", "id": "A0A8M1P9G4-1", "name": "", "aln": "MSQSPEAETVTVVPAEPASTTESASVTITTAPVTRTSFWKERRKIPEKTDEFLLARFQGDGVRYKAKLIGVDDVQDARGDKMCQDSMMKLKGMAIAARSQGKHKQRIWINISLTGIKIVDEKTGVIEHEHVVNKISFIARDVTDNRAFGYVCGAEGQHQFFAIKTAQQAEPLVIDLKDLFQLIFNMKKKEQEAGQKGEGN-GTENGGDALLAVDGNENPVKS-VEQMNLFGDMSTPPDIHSPT-PDSVLLLELSDLFDGNQ-VNQDNPFITN---------PSPLCNKPFDKSASSTSDLFPTLSSDPFSDDPFSPLNDQSDSVFS---SNNESDFSSFLLNGPDSSEDPSPKSQQFNKLFDSQLSNESPNNQVQQLPISDLNGGTNSIFSQNPFLSISLNNPPIVNGLYSSDPPVLQAPLCNGSNKQLALFQTNPSTTVQNGGLTALCPPPQNLKPRCARRREKSPGNDLFGSGLFA------PPAQNESQASNQNASIPADLFNSTPSSTINAFGSMSLGHAPGTAPVSWGQTP----TMFPPQAGVQVTIPGPPRPFPQPSAFGGLSAPAWGQQGASPFGPPAG---TQAWG-QPGAAAPVGTWPAPGPVASPFQPNQFAPMMPPNAMMGMQQGAVAPPRPPPRPPVKEEP--PVVKSAFTALDPLGEKESKSGKDMFKNFQMVKPQKPEPGP----DPNTNGSFDQYFSNKVGLAQDAADHDDFEINQISANSNGTSKPASQLIPTMDAIPQAAGLIPAPATGLLDVAFSSNPVPAPTNPAPAAGTDLFDDTFGVNPFGAPLMNTSTPATQNAALADAFGDPFGGNPFA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . *:.: * : .. . .:. ... .*****:*****:*:**:*******:*** :******.********* * *.****:****:*:****:**.: *****. ** *************.********.***********.*******:*******:*:*:**** : : * . ***. : : *:*::**********::.*: . .:**::*. :* ** : *** :. . .. :.. :: .:*** *** **** .:. * :. . . . . . : :.: ** *:**.: . . . : : :. :* . *.: . . : : * . . : *** . *. .** **..*: :. *. . . : . .**. ...:. .* . * . . . : . . * *. *. .. : .. *...: * * : . .:*.. .:..***. .. * .: . .. ..* ..**. *****:** :. *:***:**: :* . . * . : :::.: . *.:. . : : .. : . .*** ****", "identical_positions": 214, "similar_positions": 195, "identity": "25.69%" }, { "cls_id": "homologset.agr.RGD:621008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IZP0-1", "uniprot_id": "ABI1_HUMAN", "id": "Q8IZP0-1", "name": "Abl interactor 1", "aln": "------------MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAK-HGNNQPARTGTLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTP------------SPPTIGPENISVPPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTS----SGGYRRTPSVTAQFS-AQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGD---PAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZM5-1", "uniprot_id": "ABI1_RAT", "id": "Q9QZM5-1", "name": "Abl interactor 1", "aln": "------------MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK------HGNNQPARTGTLSRTNPPTQKPPSPPVSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTP------------SPPTAGP---------------------------AAPGAAPGSQYGTMTRQISRHNSTTSSTS----SGGYRRTPSVTAQFS-AQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYSDPYADGD---PAWAPKNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVESIMHYTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CBW3-1", "uniprot_id": "ABI1_MOUSE", "id": "Q8CBW3-1", "name": "Abl interactor 1", "aln": "------------MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAK-HGNNQPARTGTLSRTNPPTQKPPSPPVSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTP------------SPPTAGP---------------------------AAPGAAPGSQYGTMTRQISRHNSTTSSTS----SGGYRRTPSVAAQFS-AQPHVNGGPLYSQNSISVAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYSDPYADGD---PAWAPKNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVESIMHYTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3AND6-1", "uniprot_id": "A0A8M3AND6_DANRE", "id": "A0A8M3AND6-1", "name": "", "aln": "------------MAELQMLLEEEIPAGKRALVESYQNLTRVADYCENNYVQAQDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTARTHKIIAPANVERPVRYIRKPIDYNVLDDVGHGVKWLKAKQHGNNQSIRGGTLSRTNPPTQKPPSPPLAGRGTLGRNTSYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSIPNSIPATPSWAPPPGAPPPAPPPPPPLPGLGPPMPAAAIAVAAGPGLGPIPMSQFGTISRQVSRHNSSNSSVSMVSATGTYRRAPSVSSQFSLQQPHINGG----TPAMSMAPPPPPMPQLTPQIPLTGFVARVQENIADTPTPPPPPPPEDMVIFDEAPPPPPPPPADYEDEEAAIVHYSDPYADGD---PQWAPKSYAEKVVAIYDYTKDKDDELSFIEGAIIYIIKKNDDGWFEGVCNGVTGLFPGNYVESIMHYAD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K774-1", "uniprot_id": "A0A0B4K774_DROME", "id": "A0A0B4K774-1", "name": "", "aln": "MLTETPMASENIMDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQINTLAYSYMQLLELQAQQLGEMESQMNHIAQTVHIHKEKVARREIGVLTANKVSSRQFKIVAPINPEKPIKYVRKPIDYSMLDEIGHGIN------SAQHSQVRQKHRGSSHGSVQSLLPPSVGPPPTTKPPTPPQMSRAGNTGTLG-KSVSNTGTLGKSSREYRTPPVVNPPQVPSHYAPNYPIGHPKRMSTASSTMTTTTT----------------GGG----------------------------AAGNERAAGYSALPMPPSQQIATHVNLPSAGMMQSLPPPPPTTYDDRSSMPPAPPSPLTVSQHEMTEQSHIGMHTLGRNINRNPNRNHFSLNFARPGSQSPPLPP---------PPPPEDEHQDFGRPRTSTGPQLAPIVPEDQNLPGWVPKNFIEKVVAIYDYYADKDDELSFQESSVLYVLKKNDDGWWEGVMDGVTGLFPGNYVEPCV----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** *:. *** *:::* :** ** *******:.* :* :*: *** ** **************:** . :***::**.** .***.:***:***.************:**:** ::* .**:** * *:*::*:******.:**::***:: .::. * . :: ..*. .*.:. * *. : .. :. *: . ::... **.. **..: : *:. * : . . . *: . .::..*. . . * : :.::. *:: :: . . .*..: : * . . * * :* . :.. *:* . : .** ** **** *: .:: * . * * *.**.: ********* ******** *.:::*::*******:*** : ***********. : ", "identical_positions": 174, "similar_positions": 133, "identity": "32.16%" }, { "cls_id": "homologset.agr.RGD:621010", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80VP2-1", "uniprot_id": "SPAT7_MOUSE", "id": "Q80VP2-1", "name": "Spermatogenesis-associated protein 7 homolog", "aln": "MDGSRRVRATSVLPRYSPPCLFTGHLSTKSNAFCTDSSSLRLSTLQLVKNHMAIHYNKILSAKAAVDCSIPVSVNTSIKYADQQRREKLRKELARCEKEFKLSKSAMQTNSKMNSKFFVNSLQKPSGEPQDQDVFIEE-MTRYPSFSKSLIPSSEGLHLSLPESSKMLMSGTQKHASTSP---------SRHSGCGHGCDRRPRS----AHQFQVALAKTPSGDLLEKHSDLFSNKQSPFTPRTLKTEAKSFLSQYRYYTPAKRRKDFSDQRMEAETQTELSSFNSELGTAEKTSSKDSEVNINQVPNYTRNGAEDKIAPLPSQGQNLAWDSIQDGILQQSSERASCKLSTEFSPDSKIYSDEEELLYLSFMENVTDEILKLGLFSNRFLERLFERHIKKNKHHLEEGKMRYLLHGLKVDLGCISEEDPAKQKHFRMLNQLHFQKALISRENEFVSDEETVSHHERQQYQEALDMLSAVPKDENKMFSLPGEFLIPAHKVKHSEGVIIQQVNDETDNEASPWNENNPSVSDSVIDQETSVDVIEGDSDFERAETSRELCCLSTSLSPSGPFPSINGGSNHGKELSTLRIMGMSIED-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R0A3-1", "uniprot_id": "SPAT7_RAT", "id": "Q9R0A3-1", "name": "Spermatogenesis-associated protein 7 homolog", "aln": "---------------------------------------------------MAVHYNKILSAKAAVDCSIPVSVNASIKYADQQRREKLRKELARCEKEFKLSKSAMQTNSKMNSKFFVNSLQRPSGEPQDQDVLIEERLTRYPSFSKSLIPSPEGLHLSLPESNKILMNGTQKYPSTAP---------PRYSGCGHGYDRRPRS----AHQFQVVISKTPSGDLLEKHADLFSNNQSPFTPRTLKTEAKSFLSQYRYYTPAKRRRDFSDQRMEAETQTELSSFNSELGTAEKKSSKDSDVSIKQAPNYMRNGAEDKIAPLSLQGQNLAWDKSKDGILQPSSERAPC---TQFSPDSKIYSDEEELLYLSFMENVTDEILKLGLFSNRFLERLFERHIRKNKHHLEEGKMRYLLHGLKVDLGCISEEE---QNSFRIFNEFHFQKALTSRENRFINDTEAVNHHERQQYQEALNMLSSVPKDENKMFSFPGEFLLPAHKVKHSEGVIVQQVNDETDFEALPWDGNNPSVSDSFIDQETSVDVIEGDSDFEMVETSRELCCLSTSLSPSVPLPSIEGGSNHDKELSTLKIMEMSIED-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P0W8-1", "uniprot_id": "SPAT7_HUMAN", "id": "Q9P0W8-1", "name": "Spermatogenesis-associated protein 7", "aln": "MDGSRRVRATSVLPRYGPPCLFKGHLSTKSNAFCTDSSSLRLSTLQLVKNHMAVHYNKILSAKAAVDCSVPVSVSTSIKYADQQRREKLKKELAQCEKEFKLTKTAMRANYKNNSKSLFNTLQKPSGEPQIEDDMLKEEMNGFSSFARSLVPSSERLHLSLHKSSKVITNGPEKNSSSSPSSVDYAASGPRKLSSGALYGRRPRSTFPNSHRFQLVISKAPSGDLLDKHSELFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRKKDFTDQRIEAETQTELS-FKSELGTAETKNMTDSEMNIKQASNCVTYDAKEKIAPLPLEGHDSTWDEIKDDALQHSSPRAMCQYSLKPPSTRKIYSDEEELLYLSFIEDVTDEILKLGLFSNRFLERLFERHIKQNK-HLEEEKMRHLLHVLKVDLGCTSEENSVKQNDVDMLNVFDFEKAGNSEPNELKNESEVTIQQERQQYQKALDMLLSAPKDENEIFPSPTEFFMPIYKSKHSEGVIIQQVNDETNLETSTLDENHPSISDSLTDRETSVNVIEGDSDPEKVEISNGLCGLNTSPSQSVQFSSVKGDNNHDMELSTLKIMEMSIEDCPLDV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:***************:****.:*************:****:*******:*:**::* * *** :.*:**:****** :* :::* :. :.**::**:**.* ***** :*.*:: .*.:* .*::* .* ..* .***** :*:**:.::*:******:**::****:* **************************::**:***:********* *:*******... .**::.*:*..* .*::*****. :*:: :**. :*. ** ** ** * : .. **************:*:************************::** **** ***:*** ******* ***: *: . ::* :.*:** *. *.: .: *.. ::******:**:** :.*****::*. * **::* :* *******:*******: *: . : *:**:***. *:****:******* * .* *. ** *.** * * :.*::*..**. *****:** ***** ", "identical_positions": 325, "similar_positions": 133, "identity": "54.08%" }, { "cls_id": "homologset.agr.RGD:621011", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV48-1", "uniprot_id": "SHAN1_RAT", "id": "Q9WV48-1", "name": "SH3 and multiple ankyrin repeat domains protein 1", "aln": "--MTHSPATSEDEER----------HSASECPEGGSESDSS-----------------------PDGPGRGP---QGTRGRGSGAPGNLAS---------------------------------------TRGLQGRSMS-VPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTE-GSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLYNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGANKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRRGPP-GAGLTVPPALLRANSDTSMALPDWMVFS-APGASSSGTPGPTSGPQGQSQPSAPSTKLSSGTLRSASSPRGARARSPSRGRHP--EDAKRQPRGRPSSSGTPRDGPAGGTGGSGGPGGSLGSRGRRRKLYSAVPGRSFMAVKSYQAQGEGEISLSKGEKIKVLSIGEGGFWEGQVKGRVGWFPSDCLEEVANRSQEGRQESRSDKAKRLFRHYTVGSYDSFDAPSLIDGIDSGSDYIIKEKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKASQQAKRLPPPAISLRSKSMTSELEEMVSPWKK-------------------------------KIEYEQQPAAVPS-----------MEKKRTVYQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRSQPS------YDRPSFLPPG--PGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPAPSSSGRLTPSPRGGPFNPSSGGPLPASSPSSFDGPSPPDTRGGGREKSLYHSAALPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTSGAPSPSHHSSSGGSSGPTQAPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGS-IPSASSPTSPALPRSEPPPAGPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPD---GAGGGGSSPSPAPATSPVPPSPSPVPTPASPSGP-----ATLDFTSQFGAALVGAARREGGWQNEARRR-STLFLSTDAGDEDGGDSG-------LGPGGPPGPRLRHSKSIDEGMFSAEPYLRLE-------------SGGSSGGYGAYAAGSRAYGGSG--SSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKE------------------SSEGGG---TPQP------PPRPPSPRYDAPPPTLHHHSPHSPHSPHARHEPVLRLWG----DPARRELGYRAGLGSQEKALTASPPAARRSLLHRLPPTAPGVGPLLLQLGPEPPTPHPGVSKAWRTAAPEEPERLPLHVRFLENCQARPPPAGTRGSSTEDGPG----------------VPPPSPRRVLPTSPTS-PRGNEENGLPLLVLPPPAPSVDVDDGEFLFAEPLPPPLEFSNSFEK--------------PESPLTPGPPHPLPDPPSPATPLPAAPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGAPAAP------------------GDPPAP--GPPAP--------------------------AAPAPPAPQPGP----------------------------------------------------------------------DPPP-----------GTDSGIEEVDSRSSSDHPLETISSAS---TLSSLSAEGGGNTGGVAGGG----AGVASGTELLDTYVAYLDGQAFGGS----GTPGPPYPPQLMTPSKLRGRALGTSGNLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALSACPGPSTAGVAGGPVAVEPEVPPVPLPAASSLPRKLLPWEEGPGPPPPPLPGPLSQPQ--ASALATVKASIISELSSKLQQFGGSSTAGGALPWARGGSGGSTDSHHGGASYIPERTSSLQRQRLSEDSQTSLLSKPSSSIFQNWPKPPLPPLPTGSGVSSSTAAAPGATSPSASSASASTR----HLQGVEFEMRPP-----------LLRRAPSPSLLPASDHKVSPAPRPSSLPILPSGPIYPGLFDIRSSPTGGAGGSTDPFAPVFVPPHPGISGGLGGALSG-----ASRSLSPTRLLS--------------------LPP---DKPFGAKPLGFWTKFDVADWLEWLGLSEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRALKFFLER----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YZU1-1", "uniprot_id": "SHAN1_MOUSE", "id": "D3YZU1-1", "name": "SH3 and multiple ankyrin repeat domains protein 1", "aln": "--MTHSPATSEDEER----------HSASECPEGGSESDSS-----------------------PDGPGRGP---QGTRGRGSGAPGNLAS---------------------------------------TRGLQGRSMS-VPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTE-GSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLYNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGANKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRRGPP-GAGLTVPPALLRANSDTSMALPDWMVFS-APGASSSGTPGPTSGSQGQSQPSAPSTKLSSGTLRSASSPRGARARSPSRGRHP--EDAKRQPRGRPSSSGTPRDGPAGGTGGSGGPGGSLGSRGRRRKLYSAVPGRSFMAVKSYQAQGEGEISLSKGEKIKVLSIGEGGFWEGQVKGRVGWFPSDCLEEVANRSQEGRQESRSDKAKRLFRHYTVGSYDSFDAPSLIDGIDSGSDYIIKEKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKASQQAKRLPPPAISLRSKSMTSELEEMVSPWKK-------------------------------KIEYEQQPAAVPS-----------MEKKRTVYQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRSQPS------YDRPSFLPPG--PGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPAPSSSGRLTPSPRGGPFNPGSGGPLPASSPSSFDGPSPPDPRSGGREKSLYHSGALPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTSGAPSPSHHSSSGGSSGPAQAPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGS-LPPASSPTSPALPRSEPPPAGPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPD---GAGGGGSSPSPAPATSPVPPSPSPVPTPASPSGP-----ATLDFTSQFGAALVGAARREGGWQNEARRR-STLFLSTDAGDEDGGDSG-------LGPGAPPGPRLRHSKSIDEGMFSAEPYLRLE-------------SGGSSGGYGAYAAGSRAYGGSG--SSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKE------------------SSEGGV---TPQP------PPRPPSPRYDAPPPTLHHHSPHSPHSPHARHEPVLRLWG----DPARRELGYRAGLGSQEKALTASPPAARRSLLHRLPPTAPGVGPLLLQLGPEPPTPHPGVSKAWRTAAPEEPERLPLHVRFLENCQARPPPAGTRGSSTEDGPG----------------VPPPSPRRVLPTSPTS-PRGNEENGLPLLVLPPPAPSVDVDDGEFLFAEPLPPPLEFSNSFEK--------------PESPLTPGPPHPLPDPPSPATPLPAAPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGAPAAP------------------GDPPAP--GPPAP--------------------------AAPAPPAPQPGP----------------------------------------------------------------------DPPP-----------GTDSGIEEVDSRSSSDHPLETISSAS---TLSSLSAEGGGNTGGVAGGG----AGVASGTELLDTYVAYLDGQAFGGS----GTPGPPYPPQLMTPSKLRGRALGTSGNLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALSACSGPSTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLSQPQ--ASALATVKASIISELSSKLQQFGGASTAGGALPWARGGSGGSTDSHHGGASYIPERTSSLQRQRLSEDSQTSLLSKPSSSIFQNWPKPPLPPLPTGSGVSSSTAAAPGATSPSASSASASTR----HLQGVEFEMRPP-----------LLRRAPSPSLLPASDHKVSPAPRPSSLPILPSGPLYPGLFDIRSSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSG-----ASRSLSPTRLLS--------------------LPP---DKPFGAKPLGFWTKFDVADWLEWLGLSEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRALKFFLER----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y566-1", "uniprot_id": "SHAN1_HUMAN", "id": "Q9Y566-1", "name": "SH3 and multiple ankyrin repeat domains protein 1", "aln": "--MTHSPATSEDEER----------HSASECPEGGSESDSS-----------------------PDGPGRGP---RGTRGQGSGAPGSLAS---------------------------------------VRGLQGRSMS-VPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTE-GSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRRGPP-GTGLTVPPALLRANSDTSMALPDWMVFS-APGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHP--EDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGSLGSRGRRRKLYSAVPGRSFMAVKSYQAQAEGEISLSKGEKIKVLSIGEGGFWEGQVKGRVGWFPSDCLEEVANRSQESKQESRSDKAKRLFRHYTVGSYDSFDAPSLMDGIGPGSDYIIKEKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKAPQQAKRLPPPTISLRSKSMTSELEEM---------------------------------------EYEQQPAPVPS-----------MEKKRTVYQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPS------YERPSFLPPG--PGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGP-----ATLDFTSQFGAALVGAARREGGWQNEARRR-STLFLSTDAGDEDGGDGG-------LGTGAAPGPRLRHSKSIDEGMFSAEPYLRLE-------------SAGSGAGYGGYGAGSRAYGGGG--GSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKE------------------SSEGGG---APQP------PPRPPSPRYEAPPPTPHHHS------PHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPG----------------VPPPSPRRSVPPSPTS-PRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEK--------------PESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAP------------------GDPHPP--GPPAP--------------------------AAPAPAAPQPGP----------------------------------------------------------------------DPPP-----------GTDSGIEEVDSRSSSDHPLETISSAS---TLSSLSAEGGGSAGGGGGAG----AGVASGPELLDTYVAYLDGQAFGGS----STPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQ--ASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTR----HLQGVEFEMRPP-----------LLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSG-----ASRSLSPTRLLS--------------------LPP---DKPFGAKPLGFWTKFDVADWLEWLGLAEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRALKFFLER----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TJV6-1", "uniprot_id": "A0AB32TJV6_DANRE", "id": "A0AB32TJV6-1", "name": "SH3 and multiple ankyrin repeat domains protein 1", "aln": "MTMPLSPLSSDEEQQRMLGNSQHLYPGAEEEEEEEEEMDDDGMDEEGEEENGELEMDDEEEVDDEDDIRRGPGHLRGGREEGHRQKGTMAGRLPGDRPIRPGNPGHAANPYSSNPGPTHQTSTNQQQQQPQRKLRERSSSNAPDDTHVALMVFRIGIPDIKQTKCLRFNPDATVWKAKQQVMCSLTESLRDVLNYGLFQPATDGHDAKFLEEERPLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKASLKKFMDYIQTSAVEKVAKLIDKGLDPNYHDPDTGETPLTLAVQTEPGGSEIIRVLVMGGAHIDFRARDGLTPLHKAVRAHAHTALLTLLSLGASSDYKDSRGLTPLYHTVLIGGDTSCCETLLYHRARLGLRDENGWDETHQACQNGNSQHLEHLLFYGADSSSQNASGNTALHICALYNKESCARILLYRGAKKDTKNNSGQNSFQVAVMSGHFELGEIIKNHRESDVVPFLESPKYAPQRRESSRTLGLPHPHPFLRANSDNSMNVPDWIAFPNAAGSSIVSVQGLKHG----------------GTLRSSSSPRGARTRSPSRGRTGDRDDRSRQTRGRQGAGSISSQGTAS---------------GQRRRLYSAVPGRVFVATRSHSAQGDREISFNKGDKVKVLSVGEGGYWEGTVRGRTGWFPSDCVEEVALRSLESRSESRSERAKRLFRHYTVGSYDSFDAP---------SDYIIKEKTVLLQKKDNEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNSLMVKVVMVTRNPDMEEGVRKKIPQQSKRLSTPAIALRSKSMTSELEEMEVPHCHYQHPHYRTQGLFLVTCLTNLSCNLPNFSVCPGIPYTVDRASAPWKKKSEFESSQATEKKRTVYQMALNKLDEILAAAQQTINTNEAPGPR-VQGVKRERGRGFYN-EPNFDQTGMGMTSSGAGLGYDRGQFVSGHGPPHGMLRQKSIGVPEEEKQFLHPPAMKFARSLSVPGPDEIPPPPTTAPPEPPFSSAPPLGFRGKTSQQPSVSMSQSTSSAAHYQLYSQSVHVTHGPRDRS---------PGPPTGSGTGDLAYSHAQAHPSVPSRTASRKVIGYTGDLAGAGG-----VAGAKAAALRRGYSNAVPPTSVATVIPQQQQTTQNQPSRMD--------RSGMGVGAGGVPKGGARRGKGPLVKQSKVEDLRQGQDTLEAKVS----------------VEKSSIPIPTIIVKAPSTSSSGRSSQGSSVEAEPPPPGE---SDSSKPEPVVPPPAPTVPPPAPPSIPAPPPPSLPSLRTQESLDFTSQFGAAIVGAARRDRERFHEARRKSASFFLSAEEELSGAGGAGGRTQTSQQQLSSQPSPRLRPSKSIDEGMFSGDTFIHHTRSMPPAFGLPEYSSPAPQGDYQPKSVPADFYGAGSRQQQQQQQQQAPTTTFIHPLTGKVLDPSSPLGLALAARERALKDDGRIRRERTTEHHFTRQLSSIGAFSSSTSQPTSHISYPMASSSSATSSAAQSTNTSSYLVTSSSLAATTTSTRPPSPRILRGAGSSWSEEAGVGERADREAAGTSAPREGLRVRFSEDKT-VHTHHYQSQQYQPTFKERERERQRERS-REREREREREREIEKAQTQYQQQSSQPMTQQPRRPSFLRMESEAGAYILSLTPPSPPPTAAPMRPTAGATGESGSGTSLMVLPPPAPSVDADD-EFVFADPLPPPLEFANSFDRGLGYSAMISHNVAARQQRHPPPPPPPPPPPTSKDSFMTGFPAHTPLPSPQAGDSTTSSLTSYDSEVANLTQSAPSPSPSSPNPLPPHSPSTLQTSGPPPPPSVSPPPPPNSYHRPFGLSQSQHLYNSTHTTGRSSSPTPPLSIPAPPAYRGPPTASSTPATSVSIRGASTVTASCSTTASTTVTSPSTTAAATPHTRIATVSTVATGGSRRPSAEHHPPPSATKSGESQETVVDSGIEELDSRSSSDHHLDSILALSGSGVRERLERAGMSSIGGIGGRDGATEVDRTSGADFLESYMSYLDGQTFEMHNAKAASTASTYPKTQRYREGTRAGDLRRQTSTAPPAYHRRREEEEEEDEAEEVEEEDLSARDGYGMREGPGIARSS-VMYFDRPRTPEIKPLWGDGSTGASQTMGEGGGQ----IVGTYVEPRKLHPPMTGMKANIINELSTKLQQRSKGTENWGAQRSLSRHR--FSEDSTGALSPPSVRSSSPSPVQLSQPALSPSPTPSSQPLYSNWARSPSPQPPAASSQPPPRSHSPVSPSSYSPYPTSPKHRPVYRTKALEFQFIPSRESRKSESHHAQRRRAPSPLISPSDRPKLGP-PRPSSLPILPTTPLYSSLYDLRGSITPPS--PANPLGDPYFSPSPPLFAPSGAPPPPNSSLVVSRSLSPTHFLSGTSSPPLHPIPPPTCLSYPHLPPPSPTKPFASKPLPYWTKYDVADWLGYLNLGEHRERFLDNEIDGTHLPSLTKDDYLDLGVTRVGHRMNIERALRRVMDRLSSSTFPISALSPRNGRTNRRRDEANRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9K8-1", "uniprot_id": "A1Z9K8_DROME", "id": "A1Z9K8-1", "name": "", "aln": "-------------------------MSGSGAFDDE----------------------------------------------------------------------------------------------------------PPPEPRDGWLLVRIHVPELNVYKCLQFPSERLVWDVKQQVLASLPKELKESFNYGLFAPPANGKAGKFLDEERRLGDYP--FNGPVGYLELKYKRRVYKMLTLDERQLKALHTRANLRRFLECINGGHVEKIAKMCAKGLDPNFHCSESGDTPLTVATGAK-KPNKLLIALVNGGALLDYRTKDGSTALHRAVEHDSLEAVSTLLELGASPNYRDGRGITPLYISITRKCEAKITESLLHDHATLGIQDSQGWNEVHQACRHGLVQHLEHLLFYGADMDGRNASGNSPLHVCAVNNQEACARMLLFRGAQRGAQNFANQTPYQVAVIAGNLELAEIIENYKSEDIVPFRGPPRYNPKRRSGI-----------------------GWLSANGAAGAALLAAAGGGFG----------------GAMVGSNGAANGNNGAGGVGLMLSHQNHQQHHAGHHQQQHMHHQ--------------------HHQNHHQQLQQQQLPHLHTLQLHGP-PSPCPSEHMLGAYSSASSSLSEGSSGHRS---HEDDISIVTDKSLGDTSDIISDSSG-------VGTNSDSAACS-----------IGHPSTTVVCMEPYAGNTVGHIRLQPGDVIEVVGSTDCGLLEGYVRGTNQSG------------FFPADCVQEVSLRQKHITNVMTASTG------MAPQQQQQQHLQQAPAGSSAASYQGSPQLSLGGHSGS-----------------------------------------------------------------------------SSTLLQQPHQSPSLSVASNGSCQQPLESNEGGASGNGINNRNNNHSVGQYSSAT-------------------APRIKKSAYNAPRSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFLLTINGEDVTSASHEQVVEMIRS-------------AGALVNLTVVSPQFPHQMQASAQYLPSGAR-AGSHHLNSGPSTPQSSHRQCATLPRKMTGPGGSGPGSSSGGSVRMAPMPPRRDPKTTLSVG------RARAKSMVAGLENGGEKEDDLPHTKSNSVESIATPTP-----------------------TGIQTGPGTPVQLRTASIKARPTSSRITAAELEELFQRQQGEGSAANASRYATMMTSSRFQSGTDSGAATPPASNG-----SPMRSGPLVYGSVAEMKRKTARSKHGSGTLRGKPVATPTVGPGGAGGGR------------------------DLKRFHSTPDLHGP-------------------QLHGSASSIWQASGKGHHSQDDVATLHASLQRLNSNQGELKLGGLGAGSATGAGGAVLPP-------------------------------------PNHPPPPPPVGQVVKVETRSSVSEYESTISLQQKLKKRTENDAVTSAAIDGVQSSFNPSANAKIYASPQELRNVMAWKLRQAQEKPSQETSAGSQQPVSQYAAPTQMRPAQQQQQAQQPPTALASHYAAPQVQVQQVQQVQQSPQQS----------------APQSPPAPPLPQAAPVPAQNGNGNGSTSGAGSAPPIPEPDYSCSESDGEDENSILVARNTKLN--------------EKIALFDVPETSGNSQASGSSSNSGSASISHSLSVEEIQRIRSNLKTSKSSPNGFAKKPEEEK-----------------------------------------------------------PQQEQQQSHQ----------------------------------------------------------------------QPQQ-----------LLQPGEDECDNSSSGVSSEQEQLALA-----AGVTLPGGGKPTDTIKKK--------PSVTIVEEPKTIPDQPSSNTS-----HTTKPMAKTTISIGGG-GSAVPTATLTVKQLVQQQHAPVIQQQQQQLGSKQPVTAASTNKFTQQSNINSNVMSPQVLGRIPSHHHQQQSSNPNQKLIATQQQILQQQQQQLAHQQHLQQILKAKAAAAGGASNTAVLVAKHQQKLHKGTSSGHESEMETRSDLEDDDGDLSPSPPAKAFQRHNSLTRKQAAAIAMQRGATRTTAVSLMQLPPPLEADSDGEPSQLTLQRQQSHHPSQTHPHP----HQLQQQLQLQQQ-------------QQQQQQQQQPMAAHIVGMLPSGQLVAVASGAVAGVPGVGATAVQQGNNNLQQLCTDNLVLAPPPQFCDCNDAKHAP------QPHLPTSQYHP------------------------------QQQQQQQHQQQQQQQQQLQQQLQQQQMLQMHQRLSG----GAGAGAVGTLGRVRIVGAMPKANHHRLH-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... : * :.: . ::.** :*::: ***:* .: :* .****:.:*.:.*:: :***** *.:.*: .:**:*** * :** *: * ***::** **** .***:** ***::.*::*:: :: . :*:*:: ******:* .::*:****:*. :: ::: .* *** :*:*::** *.**:*. *: :**.**.*.:*:* **:***: : :. * **..:* **: *.:**:* ****:.* ***********: ..:*****:.**:**: *:*:***:**:***.:..:* .*..:****::*::**.*:*.*::..*:*** .*:* .:** .*: *.*:: .. * * *:: .:... ... : . * :: .:: *: : :::. :. : : : :: . :. . . . : . * .... ** * .* :. *: :* . .: *: : **: .. * * : .*.:: : * . :. ** . .* . *:...::.* :: .: : *.: ::::.*:: . . : :: : . .. :. .* ::* .:* : : . *:: :.. :: :. : . .*: : ... . .: :::.: ..... . .: * : ...: : *: * : . . : . . .. .. . ... . * .. :: : . : . : ... .:. .. . . . . . : . : . * .*...**. .: * ..: :::.* .: **: ::.* * : . .. . . : : ... . .:....* .: . . .::. *: : : .. . :. ..*.. * * . . :: . .. . .. .. ::. *: . * * .* .* * .... . . . * . : : . .:... . ... ..: . . *. : * .: : . . .: : . .* ..* * .. . . .* . . ..*. . . . : . * *: . : * . .: : . .. : : : *.*.: .*. ::: . * . .* :.* :* *. **. : : : : * .. . .. ::: : * : . . . . : : . . . . ... . : . . : . : .. . :: .: :. * * . .: *: :. . . * . . . : .. . : . : :::: :: . * :. * . :.: . . . ..* * : .. . . *..:: . : : : : * ::: :.:.:.* . ** .*: * . : ", "identical_positions": 253, "similar_positions": 596, "identity": "9.71%" }, { "cls_id": "homologset.agr.RGD:621013", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q925G1-1", "uniprot_id": "HDGR2_RAT", "id": "Q925G1-1", "name": "Hepatoma-derived growth factor-related protein 2", "aln": "-----MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYG--KPNKRKGFNEGLWEIQNNPHASYSAPLPVSSSDSEAPEADLGGGSDADKEKEARRVMTVTAVTTTATSGRTESDSDSDKNSDHSGLKRKTPVLKMSVSKRARKASSDLD-QASVSPSEED-SESP-SESEKTSDQDFTPEKKTIARAPRRAPLGGRKKKKVPSASDSDS---------RADSDGAKEEPVVTAQPSPSSSSSSSSSSASDSDVSIKKPPRGRKPAEKPPPKPRGRRSK--PERPPSTSSSDSDSDSGEVDRISEWKRRDEERRRELEARRRREQEEELRRLREQEREEKERRKE----RAERG-------GSSGEEL-EDEEPVKKRSRKARG-RGTPSSSDSEPEGELGK--EGKKLAKKSQLQGSESARKPGQKEKRGRPDEKPRARPVKVERTRKRSEGLSLDRKGEKKKEPSVEERLQKLHSEIKFALKVDNPDVRRCLSALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMAKAAEVYTRLKSRVLGPKVEALQKVNKAGAEKERADGEKV-EEQPGEQAPRELAEDEPSTDRSAPVNGEAASQKGENTEDGAQEDGQDLEDGPRGGSSEELHDSPQDSSDPARPGNEHQDHERMQLASESADDDDEDS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UMU9-1", "uniprot_id": "HDGR2_MOUSE", "id": "Q3UMU9-1", "name": "Hepatoma-derived growth factor-related protein 2", "aln": "-----MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYG--KPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEADLGCGSDVDKDKESRRVMTVTAVTTTATSDRMESDSDSDKSSDHSGLKRKTPVLKVSVSKRARRASSDLD-QASVSPSEED-SESP-SESEKTSDQDFTPEKKTAARPPRRGPLGGRKKKKVPSASDSDS---------KADSDGAKEEPVVTAQPSPSSSSSSSSSSSSDSDVSVKKPPRGRKPAEKPPPKPRGRRPK--PERPPSTSSSDSDSDSGEVDRISEWKRRDEERRRELEARRRREQEEELRRLREQEREEKERRKE----RAERG-------GSSGEEL-EDEEPVKKRSRKARG-RGTPSSSDSEPEGELGK--EGKKLAKKSQLPGSESARKPGQKEKRGRPDEKPRARPVKVERTRKRSEGLSLERKGEKKKEPSVEERLQKLHSEIKFALKVDNPDVRKCLSALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMAKAAEVYTRLKSRVLGPKVEALQKVNKAGAEKERADNEKL-EEQPGEQAPRELAEDEPSTDRSAPVNGEATSQKGENMEDRAQEDGQDSEDGPRGGSSEELHDSPRDNSDPAKPGNERQDHERTRLASESANDDNEDS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z4V5-1", "uniprot_id": "HDGR2_HUMAN", "id": "Q7Z4V5-1", "name": "Hepatoma-derived growth factor-related protein 2", "aln": "-----MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYG--KPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLD-QASVSPSEEENSESS-SESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDS---------KADSDGAKPEPVAMAR---SASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPK--PERPPSSSSSDSDSD--EVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRE----RADRGEAERGSGGSSGDELREDDEPVKKRGRKGRG-RGPPSSSDSEPEAELER--EAKKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLHSEIKFALKVDSPDVKRCLNALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMEKAAEVYTRLKSRVLGPKIEAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAEDKPSTDLSAPVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSEDLHDSVREGPDLDRPGSDRQERERARGDSEALDEES------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XXA7-1", "uniprot_id": "HDGR2_DANRE", "id": "Q5XXA7-1", "name": "Hepatoma-derived growth factor-related protein 2", "aln": "-----MPHNFRPGDLVFAKMKGYPHWPARIEDVADGAVKPPPNKIPIFFFGTHETAFLAPKDLFAYEKNQERFG--KPNKRKGFNEGLWEIQNNPHASYNTPAAASSSDSED--NQPAAASDAEEEEE-------AVVPRKAETGSDDSDSGSE-DQKKPAVKRKAPALKRPPVKKARASSSDRDGEESGSPSEPEPSPSSDSDSGKNSDQDFTPQKESGGRGGKK-PAGRGRRKKASSGSDSDSGSQSDQKAARSDSEDEKPRPAASGSESQSGSKSDSDSEPPPPPPPTRKAPQGRKKAEKPPPKPRARKPKPAPERAPS-SSSDSDSDS-DTDRVSEWKKRDEERRKELEERRKREEAEELRRLREREKEEEEKRKKDKETKVRRGSS---SSGSSSSDDEVDDHPLKKSKKPPPPPIPAPSDSDSPPPSELKKKKESQKGRQKKEKEVKEKKERPVKEKKPQRSEEKHKAKPKAEKPKRKPVR--PPEKKVEKKKEPSPEEKLQKLHTDIKFALKVDNPDIEKCLQALDELSSVQVTTHILQKNADVIATLKKIRRYKASNAVMEKATAVYNKLKLQFIG-KIETGKPK-------------------PNEKNQEE--QDAQNTDDSKPVNGESEGERKDVSESESNSKPTDQDNPDENKSPNGIRPDPDEPADQLNDSTEADPTADADVKEDSREQDEQMSSES", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAA9-1", "uniprot_id": "Q9VAA9_DROME", "id": "Q9VAA9-1", "name": "", "aln": "MGKEKAAASYSIGDLVFAKVKGYPPWPAKITKSNN------NKKYNVYFYGTGETANIKLEDLFPYASNKERFATEKIMKRAKFIEAIDQIESALRGEDSAPIDLLDG------------------------------AEPVAPPTTGDGVKTEEPKPEPGPEPATAAPVAAAAEKPKKS-------------------------------------------------GTRKTKAPPRHVDGDS---------------------------------EAGAELAPPPAKRRVPTEGLATAAAIPAAPAAATPT---------SSKKSVKKSKPTAAVTPIQKRS----RPVNNIRNEMLMVYMPTAKCLGIVINYKKPE-------------------------------------------SFESAAAEEAWMEN---ARKEALELKLKLESGQINPESMPDRIVVEPTRSEIPKQEALR-------FIEELIEHEDALFMERDFIQLSQQLRECLGLRRANVGKCLEILEQFKEVEFTKLMLLRNPECVDIMRRLRRYVGNLELWKMDLSDEVEFKERAQTIRKVS---------------------------------------------SGIYDGFKSLFNPEPESEDNFWIDFCEKVKIYKTYTKNINENLRVGMNERGYNSLVLAKEAAASAGSAPQ-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *******:**** ***:* . : :* ::*:** *** : :***.* . ::::. * ** * *.: :*:. :.. .:* .. . . . .. :: . ... : :.. . ::.: : * : * . *.** .:.:. . . : ...* * . * . .. **..* .. . :: ::*. : :: *.. : : : :: : . .* : . : . .:* : : . .* . . : . * :. *::. *. : :* ::: .* : .:: :**. *::: ::.*. :* :*.: : ::::*** .. : .:* : : : .* . : . .. : . : . : : : . ", "identical_positions": 65, "similar_positions": 163, "identity": "9.17%" }, { "cls_id": "homologset.agr.RGD:621014", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04183-1", "uniprot_id": "KITH_HUMAN", "id": "P04183-1", "name": "Thymidine kinase, cytosolic", "aln": "MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVIVAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADKYHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P27158-1", "uniprot_id": "KITH_RAT", "id": "P27158-1", "name": "Thymidine kinase, cytosolic", "aln": "MSYINLPTVLPISPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSNSFSTHDRNTMDALPACMLKDVAQEALGVAVIGIDEGQFFPDIVDFCETMANTGKTVIV-----------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ******** **************************************************.**.*******:*****:*:************************:***:***:****** ", "identical_positions": 111, "similar_positions": 8, "identity": "47.44%" }, { "cls_id": "homologset.agr.RGD:621015", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99M66-1", "uniprot_id": "B2L10_RAT", "id": "Q99M66-1", "name": "Bcl-2-like protein 10", "aln": "-----------------MG----------DPLQDRTRRLLTDYILFCARAPNTPEPLPTSVEAALLRSVTSQIQQEHQDLFNSFRDYQGNRLELVTQMADELLSNDQEFNWGRLVMLLAFVGTLMNQD--RTVKRRR-DQRNRLL-----LERDCYLIVSLLYNRLTG-RHRSWLEAHGGWDGFCQFFKNPLPPGFWRRLLIRAILSCFFATA-IFYIWKCL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0F3-1", "uniprot_id": "B2L10_MOUSE", "id": "Q9Z0F3-1", "name": "Bcl-2-like protein 10", "aln": "-----------------MADSQ-------DPLHERTRRLLSDYIFFCAREPDTPEPPPTSVEAALLRSVTRQIQQEHQEFFSSFCESRGNRLELVKQMADKLLSKDQDFSWSQLVMLLAFAGTLMNQGPYMAVKQKR-DLGNRVI-----VTRDCCLIVNFLYNLLMGRRHRARLEALGGWDGFCRFFKNPLPLGFWRRLLIQAFLSGFFATA-IFFIWKRL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HD36-1", "uniprot_id": "B2L10_HUMAN", "id": "Q9HD36-1", "name": "Bcl-2-like protein 10", "aln": "-----------------MVDQLRERTTMADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMG-QHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTA-FIYLWTRLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8W8-1", "uniprot_id": "A0A8M1P8W8_DANRE", "id": "A0A8M1P8W8-1", "name": "", "aln": "MKIVSYEISPLFAQLSWRAQSDIAGRKMSCWLREQTLLLAEDYISFCSGIQQTPPSESAEAMRYLAKEMEQQHRTKFRSLSQEFLDTCGADPSKCLQSVMRELVGDGKMNWGRVVSIFTFTGVLASELLSRGENSEG-----------------SRRLAETIADYLGG-EKQDWLVENGGWEGFCRFFHNARQLNQESSMKTALFAAAGVGLAGLTFLLVR--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:::* * **: :*: ** . .: : :. : : .:.: . : * . . * . .*.::* :.:*.*.* .. . . . :. : . * * .:: * ***:***:**:.. : : . * : :: ", "identical_positions": 27, "similar_positions": 55, "identity": "12.11%" }, { "cls_id": "homologset.agr.RGD:621016", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXQ1-1", "uniprot_id": "PDE7B_MOUSE", "id": "Q9QXQ1-1", "name": "3',5'-cyclic-AMP phosphodiesterase 7B", "aln": "------------------------------------------------------------------MSCLMVERCGEVLFESP----EQSVKCVCMLGDVRLRGQTGVPAER---RGSYPFIDFRLLNNTTHSGEIGTKK-----------------KVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGTWDFDIFLFDRLTNG--NSLVTLLCHLFNSHGLIHHFKLDMVT--LHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENVQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDS-----IPSIQIGFMTYIVEPLFREWARFTGNSTLSENMLSHLAHNKAQWKSLLSNQHRRRGSG-----QDLAGPAPETLEQTEGATP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AIQ8-1", "uniprot_id": "A0A8I6AIQ8_RAT", "id": "A0A8I6AIQ8-1", "name": "Phosphodiesterase", "aln": "------------------MPVLERYFHSAELGRRWTAPEAVLPSSLGSRPGCQQGPLPWDLPEMIRMVKLVWKSKSELQATKPRGILENEDAFHGFPGDVRLRGQTGVPAER---RGSYPFIDFRLLNNTTHSGEIGSKK-----------------KVRRLLSFQRHFHESRLLRGMTPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNG--NSLVTLLCHLFNSHGLIHHFKLDMVT--LHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENIQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDS-----IPSIQIGFMTYIVEPLFREWARFTGNSTLSESMLNHLAHNKAQWKSLLSNQHRRRGSG-----QDPAGTAPETLEQTEGATP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NP56-1", "uniprot_id": "PDE7B_HUMAN", "id": "Q9NP56-1", "name": "3',5'-cyclic-AMP phosphodiesterase 7B", "aln": "------------------------------------------------------------------MSCLMVERCGEILFENP----DQNAKCVCMLGDIRLRGQTGVRAER---RGSYPFIDFRLLNSTTYSGEIGTKK-----------------KVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNG--NSLVTLLCHLFNTHGLIHHFKLDMVT--LHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDS-----IPSIQIGFMSYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLLPRQHRSRGSSGSGPDHDHAGQGTESEEQ-EGDSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "MSTLFLIGIHEIEKSQTIVQNEHYFDRVIELQDLDSLMVALYKDRVSPFPNVHNFETGVSIVLYDPSKFQLSVRQLDVLFKRFFP--SFNISAIDHTREENLQRLECVERENSICRNRITRINHWMYHHHDDTPDGINKNSYGTVNGNSVPTQACEANIYTLLLHLNDSKAQHLRKASVPRLIRNIEFMSFLSDPIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKD---NPVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLS---ISKKKFDFISEAILATDMALHSQYEDRLMH---------ENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEFN-DCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLS-----DNVKINKEYWMKHKKPQ-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: . . : .*: * *. *. . *:. : : : : .*: :: ** . . : .:* :. *: :: .:*.:. . :*: * ::*: : .: : * : : * :. *: :. * :*. ::..** * :** ** ** ** . .*:: :* :** .***.***.*: :* : : .:*: ::*:*:***.* . :* * :::. : :.. *****: :.:: ** *: .: ::.: :*.***.* * .:* :*: : ** : * :.*. * : ** *. :: : *: : :..:. :.:. : .: : . *..:. * . * : : ", "identical_positions": 79, "similar_positions": 143, "identity": "14.36%" }, { "cls_id": "homologset.agr.RGD:621017", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07014-1", "uniprot_id": "LYN_RAT", "id": "Q07014-1", "name": "Tyrosine-protein kinase Lyn", "aln": "-----------------------------------------------------------------------MG-CIKS-KRKDNLNDDGVDMKTQPVRNTDRTIYVRDPTSNKQQRPVPESQLLPGQRFQAKDPEEQGDIVVALYPYDGIHP---DDLSFKKGEKMKVL-EEHGEWWKAKSLSSKREG---------------------FIPSNYVAKVNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETL-----------KGSFSLSVRDYDPMHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQSDG---LCRRLEKACIS-PKPQKP----WDKDAWEIPRESIKLVKKLGAGQFGEV-------WMGYYNNSTK--VAVKTLKPGTMSAQA------------------------FLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLK--SDEGSKVLLPKLIDFSAQIAEG------------MAYIERKNYIHRDLRAANVLVSES----LMCKIADFGLARVIEDNE--------------YTAREGAKFPIKWTAP---------------------EAINFGCFTIK------------SDVWSFGILLYEIVTYG-------------------------KIPYPGRTNADVMTALSQGYRMPRMENCPDELYDIMKMCWKESAEERPTFDYLQSVLDD----------------FYTATEGQYQQQP--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25911-1", "uniprot_id": "LYN_MOUSE", "id": "P25911-1", "name": "Tyrosine-protein kinase Lyn", "aln": "-----------------------------------------------------------------------MG-CIKS-KRKDNLNDDEVDSKTQPVRNTDRTIYVRDPTSNKQQRPVPEFHLLPGQRFQTKDPEEQGDIVVALYPYDGIHP---DDLSFKKGEKMKVL-EEHGEWWKAKSLSSKREG---------------------FIPSNYVAKVNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETL-----------KGSFSLSVRDYDPMHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQSDG---LCRRLEKACIS-PKPQKP----WDKDAWEIPRESIKLVKKLGAGQFGEV-------WMGYYNNSTK--VAVKTLKPGTMSVQA------------------------FLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLK--SDEGGKVLLPKLIDFSAQIAEG------------MAYIERKNYIHRDLRAANVLVSES----LMCKIADFGLARVIEDNE--------------YTAREGAKFPIKWTAP---------------------EAINFGCFTIK------------SDVWSFGILLYEIVTYG-------------------------KIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDD----------------FYTATEGQYQQQP--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07948-1", "uniprot_id": "LYN_HUMAN", "id": "P07948-1", "name": "Tyrosine-protein kinase Lyn", "aln": "-----------------------------------------------------------------------MG-CIKS-KGKDSLSDDGVDLKTQPVRNTERTIYVRDPTSNKQQRPVPESQLLPGQRFQTKDPEEQGDIVVALYPYDGIHP---DDLSFKKGEKMKVL-EEHGEWWKAKSLLTKKEG---------------------FIPSNYVAKLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETL-----------KGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADG---LCRRLEKACIS-PKPQKP----WDKDAWEIPRESIKLVKRLGAGQFGEV-------WMGYYNNSTK--VAVKTLKPGTMSVQA------------------------FLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLK--SDEGGKVLLPKLIDFSAQIAEG------------MAYIERKNYIHRDLRAANVLVSES----LMCKIADFGLARVIEDNE--------------YTAREGAKFPIKWTAP---------------------EAINFGCFTIK------------SDVWSFGILLYEIVTYG-------------------------KIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDD----------------FYTATEGQYQQQP--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V9J3-1", "uniprot_id": "SRC42_DROME", "id": "Q9V9J3-1", "name": "Tyrosine-protein kinase Src42A", "aln": "-----------------------------------------------------------------------MGNCLTTQKGEPDKPADRIKLDDPPTIGVG-VGVPQIPMPSHAGQPPEQIRPVP-QIPESETAGANAKIFVALYDYDARTD---EDLSFRKGEHLEILNDTQGDWWLARSKKTRSEG---------------------YIPSNYVAKLKSIEAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESR-----------HNDYSLSVRD-----GDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDG---LCVNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDV-------WEGLWNNTTP--VAIKTLKSGTMDPKD------------------------FLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAG------------MAYLESQNYIHRDLAARNVLVGDG----NIVKIADFGLARLIKEDE--------------YEARVGARFPIKWTAP---------------------EAANYSKFSIK------------SDVWSFGILLTELVTYG-------------------------RIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLED----------------FYTSDQSDYKEAQAY------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AC58GD28-1", "uniprot_id": "A0AC58GD28_DANRE", "id": "A0AC58GD28-1", "name": "Trimethylguanosine synthase", "aln": "MMIDYGERNVVPLADIIFYQGEETEMTIHCLCSRAYVNDRELYRSDFKAISSQADSQVQGDVETNDGEQLLEDLNCSVDEDEEEEEEEEDAAVDEETLLMASLGLPVQFASSSKQRRAGQVLARPKNKRTVKCLETSSDYTDANENSEDIAEPPCEQICPTSDEAWLRYWQQHGEGLLWQSWLEKHPENSSSTVQDFSHSQTDWDDHFQQIYKYYWEQFQYWAAQGWTLDESYSTTAASEENQNCQGETEALESETKDRSKADASSVTHLISSLSLLTEEVDMDDGRQPLVCSCADEPCDGGNRKRPSSRAACTDASDGNMKQTSGSAPMNNGSGRPTKSRSNDEDQSDDDDDDEPPGNRRAKVKRAHELDAEEIAEVPVEEAWDALGLRRGSQPKFESVVKLKAGQGSYTGRRREDRKPPEQRRKAACKINKHIFFTDDGPQTTKPKISKALQKVQSFLQQVQTDADSEDVATTSMPEALIGPFDKAELASLPTRKEDEEEASNDTDEEDCETTPQPSRICEEQQHIIPDLEEIHEDEADPRGELQPLDVPDFLLPDAHEDTKKESVQAFKKNKRKKRKRRKDVEMPPEIAAEPELAKYWAQRYRLFSRFDEGIKLDHEGWFSVTPEKIAEHIALRVQDCFNTELIIDAFCGVGGNAIQFALTGKRVIGIDIDPVRLALAQHNAAVYGVEQRIDFLQGDFLQLAPHLRGDMVFLSPPWGGPEYLTADVFNIQTMMTPDGFEIFRLSKMISDNIVYFLPRNADMEQIASLAGPGGKVEVEQNFLNNKLKTITAYFGNLIK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . : . .. : : * : : ... * : :::. ..* : :*: :* : * . * :.: :: * : . * : : * ::: .. ** ..: * . .* : : . *::.* : :. . : : * .:* .:.*.: ::.:* * ..: :: .**.* . * :. .. : * :: : :* : *: : * .:. : . : : : . * :::* ** : .: .:.** *. :: : * ...:* : :* : : . *::. .* :. ::: : * .. ..: . :* : : : : . .*: * :: . :.: :: ", "identical_positions": 45, "similar_positions": 154, "identity": "5.62%" }, { "cls_id": "homologset.agr.RGD:621018", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62599-1", "uniprot_id": "MTA1_RAT", "id": "Q62599-1", "name": "Metastasis-associated protein MTA1", "aln": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSSLIALADKHATLSVCYR-------------------------------------------AGPGADTGEEGEVEEEVEN----------------------PEMVDLPEKLKHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKDGEEDGRDQSKLETKVWEAHNPLVDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQISVNSVKASVVNGTG-TPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRNNMSPHGIP-----------------------------------------------------------ARSSGSPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYMPINSAAIKAECTARLPEASQSP----LVLKQVVRKPLEAVLRYLET------------------------HPRPPKP-------DPVKSSSSVLSSLTPAKSAPVINNGSPTILGKRSYEQH--NGVDG----------------LANHG----QTRHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALR-----------QSQALPLRPPPPAPVNDEPIVIED--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4B0-1", "uniprot_id": "MTA1_MOUSE", "id": "Q8K4B0-1", "name": "Metastasis-associated protein MTA1", "aln": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSSLIALADKHATLSVCYR-------------------------------------------AGPGADTGEEGEVEEEVEN----------------------PEMVDLPEKLKHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKEGEEDGRDQSKLETKVWEAHNPLVDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQISASSVKATVVNGTG-TPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRNNMSPHGIP-----------------------------------------------------------ARSSGSPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYMPINSAAIKAECTARLPEASQSP----LVLKQVVRKPLEAVLRYLET------------------------HPRPPKP-------DPVKSSSSVLSSLTPAKSAPVINNGSPTILGKRSYEQH--NGVDGNMKKRLLMPSRG----LANHG----QTRHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALR-----------QSQALPLRPPPPAPVNDEPIVIED--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13330-1", "uniprot_id": "MTA1_HUMAN", "id": "Q13330-1", "name": "Metastasis-associated protein MTA1", "aln": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALADKHATLSVCYK-------------------------------------------AGPGADNGEEGEIEEEMEN----------------------PEMVDLPEKLKHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTG-APGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLP-----------------------------------------------------------ARSSGSPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSP----LVLKQAVRKPLEAVLRYLET------------------------HPRPPKP-------DPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQH--NGVDGNMKKRLLMPSRG----LANHG----QARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALR-----------QSQALPPRPPPPAPVNDEPIVIED--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4KG70-1", "uniprot_id": "A0A0B4KG70_DROME", "id": "A0A0B4KG70-1", "name": "Metastasis-associated protein MTA3", "aln": "MATNMYRVGDYVYVETTPNSPYLIRRIEELNKNQTGNVEAKVMCFYRRRDLPNPLVQLADKHQLATAEDSPLATKLKKTWLRTPVSEEQAAQAVLDPSIAALDEERTSPTQTSGGGGSATGNSGSNSSGTSNNNSSSTAIGGGAGGSGGAGGDAEKGEALTSKQRYQIKHRELFLSRQVESIPATQIRGKCSVTLLNETESLQSYLNKDDTFFYCLVFDPNQKTLLADKGEIRVGSRYQCDIPAKLKDTATDDRKLEELESLVWTPEHSLTDRKIDQFLVVSRSIGTFARALDCSSSVKQPSLHMSAAAASRDITLFHAMNILHKHEYSIEESMSSLVPSTGPVLCRDEIEDWSASEANLFEEALEKYGKDFNDIRQDFLPWKTLKQIIEYYYMWKTTDRYVQQKRVKAVEAELKLKQVYIPQYNNNGKGNGTSTKAGGGIYNGTTNGSTDLSSNGKPCESCGTTKSSQWNSVSSGHSTSRLCLSCWEYWRRYGSMKSATKGDAGEGDAKKKSSSAASTPTATLAGLATTPTAVVDLNDDEKISDLTNRQLHRCSIVNCGKEFKLKTHLARHYAQAHGIAISSGSPRPIMKTRTAFYLHTNPMTRVARAICRSIVKPKKAARQSAYAINAMLVKQEFTNRISGKSQAEIKKLLLLKPKDRGSVTKIANRLGAPGSGPHEWLVLTPKDKMPLPAVVSFPKPPKAPDGSLVYDRVPNKSPDVVAVPADKELTIIPTQATSTIRKRAHEDQQLNGTEVTIVPSGPPAKRPNKDPMPSHCPSPEQFAAMMAASGQPLSRHHLNGKQKIAQMARGGNGRKQVISWMDAPDDVYFRANDTHKKTRKILSAVDLRRAARKPWRTLPIKPAAPEPSSRPIESQIVILDXPSPASTLTASAASATKLLSSSASRFEQQHPPFPYTMDALLN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**********.*.:...************. .*******:*******:...*: ***** :. .* *: .*:.*. .. .* : *..* ::*::*********:**:***:****************:***:::* ***.**:**:**************.***.**. **: *.*. ..**: ** ..:.*.*::*******:**:*************:*********************: ***: *.*.:::*:***. ********:*:********************.**:*******:*..*******************:**.*** ********:**: . .: : ... . : *** . : .. *:.**** **:* ** * .. : .*** *** **::**.:* .*: *. . ..::.. *. . * * *****: **** ******. :**:** :**.*::* :***:. .**: :* * * *:. **: *:** * .: : . * : .*:***. * * . *. : ::.. * .:* . :.: : **::*:: **.: :..* * * .: . *. : * :: : . ::: :.*:******:: *.: :* **:**: : :****:*::.:.:: :** : *.**.. . . ", "identical_positions": 359, "similar_positions": 206, "identity": "38.94%" }, { "cls_id": "homologset.agr.RGD:621019", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70452-1", "uniprot_id": "STX4_MOUSE", "id": "P70452-1", "name": "Syntaxin-4", "aln": "-MRDRTHELRQGDNISDDEDEVRVALVVHSGAARLGSPDDEFFQKVQTIRQTMAKLESKVRELEKQQVTILATPLPEE--SMKQGLQNLREEIKQLGREVRAQLKAIEPQKE-EADENYNSVNTRMKKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQ--VTRQALNEISARHSEIQQLERSIRELHEIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKIALENQKKARKKKV-MIAICVSVTVLILAVIIGITITVG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q08850-1", "uniprot_id": "STX4_RAT", "id": "Q08850-1", "name": "Syntaxin-4", "aln": "-MRDRTHELRQGDNISDDEDEVRVALVVHSGAARLSSPDDEFFQKVQTIRQTMAKLESKVRELEKQQVTILATPLPEE--SMKQGLQNLREEIKQLGREVRAQLKAIEPQKE-EADENYNSVNTRMKKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQ--VTRQALNEISARHSEIQQLERSIRELHEIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKIALENQKKARKKKV-MIAICVSVTVLILAVIIGITITVG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12846-1", "uniprot_id": "STX4_HUMAN", "id": "Q12846-1", "name": "Syntaxin-4", "aln": "-MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQELEKQQVTILATPLPEE--SMKQELQNLRDEIKQLGREIRLQLKAIEPQKE-EADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQ--VTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKV-LIAICVSITVVLLAVIIGVTVVG---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24547-1", "uniprot_id": "STX1A_DROME", "id": "Q24547-1", "name": "Syntaxin-1A", "aln": "MTKDRLAALHAAQ--SDDEEETEVAVNVDG----HDSYMDDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSAPQTDE--KTKQELEDLMADIKKNANRVRGKLKGIEQNIEQEEQQNKSSADLRIRKTQHSTLSRKFVEVMTEYNRTQTDYRERCKGRIQRQLEITGR-PTNDDELEKMLEEGNSSVFTQGIIMETQ--QAKQTLADIEARHQDIMKLETSIKELHDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARRKKI-MILICLTVLGILAASYVSSYFM----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39926-1", "uniprot_id": "SSO2_YEAST", "id": "P39926-1", "name": "Protein SSO2", "aln": "--MSNANPYENNNPYAENYEMQEDLNNAPTGHSDGSDDFVAFMNKINSINANLSRYENIINQIDAQHKDLLTQVSEEQEMELRRSLDDYISQATDLQYQLKADIKDAQ----------RDGLHDSNKQAQAENCRQKFLKLIQDYRIIDSNYKEESKEQAKRQYTIIQPEATDEEVEAAINDVNGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKTMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQQDVEQGVGHTNKAVKSARKARKNKIRCLIICFIIFAIVVVVVVVPSVVETRK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32867-1", "uniprot_id": "SSO1_YEAST", "id": "P32867-1", "name": "Protein SSO1", "aln": "--MSYNNPYQLETPFEESYELDE--GSSAIG-AEG-HDFVGFMNKISQINRDLDKYDHTINQVDSLHKRLLTEVNEEQASHLRHSLDNFVAQATDLQFKLKNEIKSAQ----------RDGIHDTNKQAQAENSRQRFLKLIQDYRIVDSNYKEENKEQAKRQYMIIQPEATEDEVEAAISDVGGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKSMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQLDVEQGVGHTDKAVKSARKARKNKIRCWLIVFAIIVVVVVVVVVPAVVKTR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. : . *: :: *. : : :.::. : :*: :: :: *:: : .. .:: .:* : .. . :::* ::*:::: . . :::*:*. : :** * ..:: : : . ..:* . :: .: :: :* ::.***.:: :** :: ** ::* : * * * :: *: :: : *: . ... *:: ***::*: * . : :: . : . ", "identical_positions": 33, "similar_positions": 109, "identity": "10.75%" }, { "cls_id": "homologset.agr.RGD:621020", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PCU8-1", "uniprot_id": "NDUV3_RAT", "id": "Q6PCU8-1", "name": "NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVSLLLRGGRIRALKAALLEAKVFRGELASTVP--------------------------LSTESENNKKAAG------------------------PTSKTESVFKEPTLV-PESSDTTTYKNLQHHEYNAFTFLDLNLDLSKFRLPQPSSGRESPRH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BK30-1", "uniprot_id": "NDUV3_MOUSE", "id": "Q8BK30-1", "name": "NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVSLLLRGGRIRALKAVLLEARVFPGELVSVVR--------------------------LSTESEKSAKEKE------------------------LHPKTQSVLKE-----PEPTDTTTYKNLQHHDYNTYTFLDLNLDLSKFRLPQPSSGRESPRH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56181-1", "uniprot_id": "NDUV3_HUMAN", "id": "P56181-1", "name": "NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAPCLLRQGRAGALKTMLQEAQVFRG-LASTVS--------------------------LSAESGKSEKGQP------------------------QNSKKQSPPKKPAPVPAEPFDNTTYKNLQHHDYSTYTFLDLNLELSKFRMPQPSSGRESPRH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BCF6-1", "uniprot_id": "A0A8M3BCF6_DANRE", "id": "A0A8M3BCF6-1", "name": "", "aln": "MAMSLLRLGRLGSVKCLLRGGWSPPKTQFAAALCTKADVPPKTPKKGKASSKSKTIEADERASLLAYKPAVAFPSKLVATGFLSKDVALGESETAKAAFTTPANEKTTDSPPADTAAADVAVEEPKITEIPTTGKAPTEGERSKALDPDSEAKKDDEDTSSSSSSSSDSDSDSDDEEPKTEPPQQTGEKAEKKDSSVANEQVDLADKIAKPVSASFKEECVETVKSTPEVLAPSAKPVGSAETLVDPAPIVSSSATHAISAPSPKVSSSATEAISAPVPIVSSSETETISDPVPKVSTSATEAIPDPAPKVSSSATEAIPDPAPKVSSSATETIHDPAFKVSSSATQAIPEAPGESLNVGTPDIIADIPAKEVKTVPTEESIIKAEEAASVVPEVSTKASHLASPPEAPGDVAPKSEDLSAKAEAGAPSAPSEELVDPAPAAADAVEALAQTDVVETPEEQAPEKAPEPE-PEPFDNTTYKNLQHHNYNMYTFTDMDVEMAKYRLPQPSSGRPSPQH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :... :: :*: * :: . .: * **::: . .: :: * .*. *.*********:*. :** *::::::*:*:******* **:*", "identical_positions": 33, "similar_positions": 36, "identity": "6.38%" }, { "cls_id": "homologset.agr.RGD:621021", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63249-1", "uniprot_id": "IPKA_RAT", "id": "P63249-1", "name": "cAMP-dependent protein kinase inhibitor alpha", "aln": "MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEDDGQRSSTEQSGEAQGEAAKSES-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63248-1", "uniprot_id": "IPKA_MOUSE", "id": "P63248-1", "name": "cAMP-dependent protein kinase inhibitor alpha", "aln": "MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEDDGQRSSTEQSGEAQGEAAKSES-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61925-1", "uniprot_id": "IPKA_HUMAN", "id": "P61925-1", "name": "cAMP-dependent protein kinase inhibitor alpha", "aln": "MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRSSTEQSGEAQGEAAKSES-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NWK5-1", "uniprot_id": "A0A8M1NWK5_DANRE", "id": "A0A8M1NWK5-1", "name": "", "aln": "MTDVEVTYEDFIASGRTGRRNAVHDILGSSGGLDASGLSQTLSELSIGKPGNDEEKDQRSTDS--EPKQEEANGEGT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.** *************:**** **.. ::. *: .*: *.*.*. .::: :: **:. *.: * *:.*. ", "identical_positions": 37, "similar_positions": 26, "identity": "48.05%" }, { "cls_id": "homologset.agr.RGD:621022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LS86-1", "uniprot_id": "F1LS86_RAT", "id": "F1LS86-1", "name": "Isoleucine--tRNA ligase, cytoplasmic", "aln": "MVQQVPENISFPAEEEKILQFWSKYNCFQECLKQSKLRPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRAIVMRYSAEWKSTVTRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACGTPLSNFESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCVNPEIQYVKIKDVSRGKLFILMEARLSALYKQ--ESDYEILERFPGASLKGKKYKPLFDYFIKCKENGAFTVLVDHYVKDEEGTGVVHQAPYFGADDHRVCMDFNIIQKDSAPVCPVDASGCFTEEVTHFVGQYVKDADKNIIRMLKEQGRLLVASTFTHSYPFCWRSDTPLIYKSVPSWFVRVEHMVDQLLKNNDLCYWVPEFVREKRFGNWLKEARDWAISRNRYWGTPIPLWVSEDFEEVVCIGSVAELEELSGTK-ISDLHRESIDHLTIPSRCGKGPLRRVSEVFDCWFESGSMPYAQVHYPFESKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLILASDGQKMSKRKKNYPDPVSIINKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFFIQNVFRLHKEEEVEFLYNEHTVRESPNITDRWILSFMQSLIAFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKLLIDPASIRD--KDTLSIHYLMLPHVREELIDKKTENAVSRMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALEDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMVAVKQLSNEELEQFQKSGSIVVEGHELHEEDIRLMYTFDQATGGTAQFEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKSEGRYLSNVIESHTDFIYATIKAPLKPYPVPTSDNILIQEQTQLKGYELEITITRGSC--------VPGPACAYVNLNICANGTEQGGVLLLENPKGDNQLNLEKLKSVITSIFGVKSTGLSVFNGGTELQNQTDLLSLSGRTLCVT--AGASLAPASSPSTLLCQYINLQLVNAEPQECLTGTVGTLLLENPLGQNGLTHQGLVYEAAKVFGLRSRRLKLFLNETQTQEITEDIPMKTLNMKTVYVSVLPTTADG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BU30-1", "uniprot_id": "SYIC_MOUSE", "id": "Q8BU30-1", "name": "Isoleucine--tRNA ligase, cytoplasmic", "aln": "MVQQVPENISFPAEEEKILEFWSKHNCFQECLKQSKLRPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRAIVMRYSAEWKSTVTRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACGTPLSNFESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCVNPEIQYVKIKDVARGKLFILTEARLSALYKQ--ESDYEILERFPGASLKGKKYKPLFDYFIKCKENGAFTVLVDHYVKDEEGTGVVHQAPYFGADDHRVCMDFNIIQKDSVPVCPVDASGCFTEEVTHFVGQYVKDADKNIIRMLKEQGRLLAAGTFTHSYPFCWRSDTPLIYKSVPSWFVRVEPMVDQLLKNNDLCYWVPEFVREKRFGNWLKEARDWAISRNRYWGTPIPLWVSEDLEEVVCIGSVAELEELSGTK-ISDLHRESIDHLTIPSRCGKAPLRRVSEVFDCWFESGSMPYAQVHYPFESKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLILASDGQKMSKRKKNYPDPVSIIDKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFFIQNVFRLHKEEEVKFLYNEHTVRESPNITDRWVLSFMQSLLGFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGESGVEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKLLIDPASLRD--KDTLSIHYLMLPRVREELIDKKTENAVSRMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALEDIRSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMMAIKRLSNEELERFQKSGSIVVEGHELHEEDIRLMYTFDQATGGTAQFEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKSEGRYLNNVIESHTDFIFATIKAPLKPYPVPTSDNILIQEQTQLKGSELEITLTKGSC--------VPGPACAYVNLNICANGTEQGGVLLLENPKGDNQLNLVKLKTVVTSVFGVKNAKLSVFHGETEIQNQTDLLSLSGRTLCVT--AGASPSPISSPSTLLCQYLNLQLLNAEPQECLTGTVGTLLLENPLGQNGLTHQGLVHEAAKVFGLRSRRLRLFLNETQTQEITEDIPMKTLNMKTVYVSVLPTTADG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41252-1", "uniprot_id": "SYIC_HUMAN", "id": "P41252-1", "name": "Isoleucine--tRNA ligase, cytoplasmic", "aln": "MLQQVPENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARLSALYKL--ESDYEILERFPGAYLKGKKYRPLFDYFLKCKENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEELSGAK-ISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFLIQNVLRLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKVLIDPVSVQD--KDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGTAQFEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYLNSVIESHTEFIFTTIKAPLKPYPVSPSDKVLIQEKTQLKGSELEITLTRGSS--------LPGPACAYVNLNICANGSEQGGVLLLENPKGDNRLDLLKLKSVVTSIFGVKNTELAVFHDETEIQNQTDLLSLSGKTLCVT--AGSAPSLINSSSTLLCQYINLQLLNAKPQECLMGTVGTLLLENPLGQNGLTHQGLLYEAAKVFGLRSRKLKLFLNETQTQEITEDIPVKTLNMKTVYVSVLPTTADF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UZX0-1", "uniprot_id": "A0A8N7UZX0_DANRE", "id": "A0A8N7UZX0-1", "name": "Isoleucine--tRNA ligase, cytoplasmic", "aln": "MVEAVPESIHFPTEEEQILQFWQKNDCFQECLKQSKSRPRFTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQNGFHVERRFGWDCHGLPVEYEIDKSLNIKGPEDVMKMGIEEYNKQCRSIVMRYADEWENSVRRMGRWIDFRNDYKTLYPWFMETVWWVFKQLYDSGLVYRGVKVMPFSTACNTPLSNFEANQNYKDVQDPSVIVNFPLLEDPSVSLIAWTTTPWTLPSNLALCVNPELIYVRVKDNSSQKIYIMMEARLVALFKS--DSEYTILERFPGKTLKGKKYKPLFEYFIKCKETGAFSVVMDNYVRDDDGTGVVHQAPYFGADDYRVCMEYDIIQRDSAPICPVDPSGIFTPEVTHFAGQYVKDADKNIIKWLKENGRLVSASSFKHSYPFCWRSDTPLIYKAVPSWFIRVEHMVEKLLDNNSKCYWVPEFVKEKRFGNWLRDARDWAVSRNRYWGTPIPLWVSDDFEEVVCVGSMAELEELTGIK-VTDLHRESIDGLTIPSRCGKGQLRRVSEVFDCWFESGSMPYAQVHYPFENRREFEDAFPADFIAEGIDQTRGWFYTLLVLSTALFGKPPFKNVIVNGLVLASDGQKMSKRKKNYPDPGLIVQSYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVFLPWYNAYRFLVQNVQRLQKEEGVEFLYNERTSSVSNNIMDKWIQSFTQSLIQFFRDEMGAYRLYTVVPKLVKFVDMLTNWYVRMNRRRLKGESGSEDCVRALETLFSVLFSMCRLMAPFTPFITELMYQNLRHLLDPAAVEE--KDTGSIHYLMLPQVRESLIDQRIESAVSRMQSVIELGRVIRDRKTLPIKYPLKEVVVIHQDPEALTDIQSLQNYILEELNVRQLTLSTDKDRYGIRLRAEPDHMVLGKRLKGAFKSVTASIKELKSEELEEFQKTGCIVVDGHDLREEDLRLMYTFDQSSGSASQYEAHSDAQVLVLLDVTPDQAMLDEGVAREVINRIQKLRKKGHLVPSDEITVFYRCQPAGEYLHQVIEAHTDFILATTKAPLRAYPVCPNASVIVQENTQLKGSDLELTIVRGSSSSSVCRAPVSGSACAFVNLRVSLKDKQQDGVVLLENPKGDNRLDLEQLKRICCSVFGLNGAPVSIFNGKTALSSSTDLLSLSGRTLTVSSAAGSSPADVSSSESLLCPYVNLQLVNASPAECRTGDVATLLLMNPEGKNLLQFSDLLRETAKVFGLRGRRLMLYTDPQLTAELKASS-MKTLNSKTLYVKVLPTTAEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09436-1", "uniprot_id": "SYIC_YEAST", "id": "P09436-1", "name": "Isoleucine--tRNA ligase, cytoplasmic", "aln": "-MSESNAHFSFPKEEEKVLSLWDEIDAFHTSLELTKDKPEFSFFDGPPFATGTPHYGHILASTIKDIVPRYATMTGHHVERRFGWDTHGVPIEHIIDKKLGITGKDDVFKYGLENYNNECRSIVMTYASDWRKTIGRLGRWIDFDNDYKTMYPSFMESTWWAFKQLHEKGQVYRGFKVMPYSTGLTTPLSNFEAQQNYKDVNDPAVTIGFNVIGQEKTQLVAWTTTPWTLPSNLSLCVNADFEYVKIYDETRDRYFILLESLIKTLYKKPKNEKYKIVEKIKGSDLVGLKYEPLFPYFAEQFHETAFRVISDDYVTSDSGTGIVHNAPAFGEEDNAACLKNGVISEDSVLPNAIDDLGRFTKDVPDFEGVYVKDADKLIIKYLTNTGNLLLASQIRHSYPFCWRSDTPLLYRSVPAWFVRVKNIVPQMLDSVMKSHWVPNTIKEKRFANWIANARDWNVSRNRYWGTPIPLWVSDDFEEVVCVGSIKELEELTGVRNITDLHRDVIDKLTIPSKQGKGDLKRIEEVFDCWFESGSMPYASQHYPFENTEKFDERVPANFISEGLDQTRGWFYTLAVLGTHLFGSVPYKNVIVSGIVLAADGRKMSKSLKNYPDPSIVLNKYGADALRLYLINSPVLKAESLKFKEEGVKEVVSKVLLPWWNSFKFLDGQIALLKKMSNIDFQYDDSVK--SDNVMDRWILASMQSLVQFIHEEMGQYKLYTVVPKLLNFIDELTNWYIRFNRRRLKGENGVEDCLKALNSLFDALFTFVRAMAPFTPFLSESIYLRLKEYIPEAVLAKYGKDGRSVHFLSYPVVKKEYFDEAIETAVSRMQSVIDLGRNIREKKTISLKTPLKTLVILHSDESYLKDVEALKNYIIEELNVRDVVITSDEAKYGVEYKAVADWPVLGKKLKKDAKKVKDALPSVTSEQVREYLESGKLEVAGIELVKGDLNAIRGLPES-AVQAGQETRTDQDVLIIMDTNIYSELKSEGLARELVNRIQKLRKKCGLEATDDVLVEYELVKDTIDFEAIVKEHFDMLSKTCRSDIAKY--------------------------DGSK----------------------------------TDPIGD------EEQSINDTIFKLKVFKL---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : ** ***::*.:* : :.*: .*: :* :*.*:*:******** ********.******.*:* .*.**:****** **:*:*: ***.*.* * :** * *: :**::**:*** *: :*..:: *:****** *****:** ***:.**.****::.* ****.****:**. *******::******:**:* : * : : ...*:*************::***.:: **:: * : : *: *: : :*:* :..* *:*:: * * * **.*** ** : . ** *: *.** .:.***:**:** ** :* .*:. .:* .** .:* * ** :*..* * ******* **: *.: *.*: * : *************:*::**:**:**: :* ::* . .:***: ::****.**: :**** :***************:*:*****:**: *****:* : ::****: :* *****: **. *:*:.***************. *****. .:*:: .**:**:**:********** **.* ***. *:*****.*::**:**:**** ****** :::.***************::**.*:******::*:..*:***:*:::*: :: *:* . :.* *:: . * *: *:*: : ***: *:. **. *:******:*::*:* *****:*:********.* ***: **::**..*::: * ***:***::* :* .*: : . : . ** *:*:* * *::. :*: *.***:*****:*** **::**:.:* *** :*::*.* . * *:.:*::**:******.:.:::*: :**:. :* .* ****:** * * :: :..*::..: ::* : * * :* . *:. : : :: . : *:::* :.*:::*.. . : .**:***::********* * .:*:: * *. : ::: * ::: * :: : * ** :* ** : : : ::* :: : ", "identical_positions": 519, "similar_positions": 327, "identity": "40.64%" }, { "cls_id": "homologset.agr.RGD:621023", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAN8-1", "uniprot_id": "F1MAN8_RAT", "id": "F1MAN8-1", "name": "Laminin subunit alpha-5", "aln": "MAKRGGQLCVGCAPGARGPRSLAPLP-LLLLAGLALVGEARI--PGGDGFSLHPPYFNLAEGARITASATCGEEAPTRSASRPTEDLYCKLVGGPVAGGDPNQ-TIQGQYCDICIAANSNKAHPVSNAIDGTERWWQSPPLSRGPEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSTDFGHTYQPWQFFASSKRDCLERFGPRTLERITQDDDVICTTEYSRIVPLENGEIVVSLVNGRPGARNFSYSPVLRDFTKATNIRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADVCDAKDPSDPFR-LQCACQHNTCGGSCDRCCPGFNQQPWKPATTDSANECQSCNCHGHAYDCYYDPEVDRRNASQNLDNVYQGGGVCLDCQHHTTGINCERCVPGFYRAPDQPLDSPHVCQPCDCESDFTDGTCEDLTGRCYCRPNFTGERCSACAEGYVDFPHCYPLPSFPHNDTGEQVLPAGQIVNCDCNAAGTQGNACRKDPRLGRCVCKPNFQGNHCELCAPGFYG-PSCHPCQCSSPGVANGLCDPESGQCTCRTGFEGDKCDHCALGYFHFPLCQLCGCSPAGTLPQGCD-ESGHCQCRPGFDGPHCDRCLPGYHGYPDCHACACDPRGSLDQQCGAGGLCHCRPGYTGATCQECSPGFYGFPSCIPCHCSADGSMHTTCDPTTGQCRCRPRVTGLRCDMCVPGAYNFPYCEAGSCHPAGLAPANP--ALPEAQAPCTCRAHVEGPSCDRCKPGYWGLSSSNPEGCTRCSCDPRGTLGGVTECQ-GNGQCFCKAHVCGKTCAACKDGFFGLDHADYYGCRSCRCDVGGALGQGCEPKTGACRCRPNTQGPSCSEPAKDHYLPDLHHIRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAHMTAIQPRIVARLNVTSPDLFRLVFRYVNRGSTSVNGQVSVREEGKFSSCTNCTEQSQPVAFPPSTEPAFVTVPQRGFGEP--FVLNPGTWALLVEAEG-VLLDYVVLLPSTYYEAALLQHRVTEACTYHPSALHPTENCLLYAHLPLDGFPSAAGTEALCRHDNSLPRPCPTEQLSPLHPPLATCAGSDVDIQLEMAVPRPGRYALVVEYVSE-YSHQEMGVAVHTPQRAPQQGMIDLHPCPYSSLCRGPARDTQHHLAVFHLDSEASIRLT----AEQAHFFLHSVTLIPVEEFSAEFVEPRVFCVSSHGAFNPGSAACLASRFPKPPQPIVLKDCQVLPLPPDLPLTQSQELSPGASPVGPQPRPPTAVDPNAEPTLIRHPQGTVVFTTQVPTLGRYAFLLHSYQPVHPSFPVEVLIDGGR-IWQGHANASFCPHGYGCRTLVSCEGQTMLDVTDNELAVTVRVPEGRWLWLDYILVVPEDAYSSSYLQEEPLDKSYDFISHCATQGYHISPSSSSLFCRNAATSLSLFYNNGALPCGCHEVGAVGPTCEPFGGQCPCRGHVIGRDCSRCATGYWGFPNCRPCDCG-ARLCDELTGQCICPPRTVPPDCLVCQPQSFGCHPLVGCEECNCSGPGVQELTDPTCDMDSGQCRCRPNVAGRRCDTCAPGFYSYPSCRPCDCHEAGTMASVCDPFTGQCHCKENVQGSRCDQCRVGTFSLDAANPKGCTRCFCFGATERCGNSNYARHEFMDMEGWVLLSSDRQVVPHEHRPEMELLHADLR----LVADTFPELYWQAPPSYLG---------DRVSSYGGTLHYELHSETRRGDVFIPYESRPDVVLQGNQMSIAFLELAYPSPGQVHRGQLQLVEGNFRHLETHNPVSREELMMVLAGLEQLQIRALFSQTSSTVSLRRVVLEVASEAGGGP---PASNVELCMCPANYRGDSCQECAPGYYRDTKGLFLGRCVPCQCHGHSDRCLPGSGTCVGCQHNTEGDQCERCRPGFVSSDPSDPASPCVSCPCPLAVPSNNFADGCILR--NGRTQCLCRPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNMIFSDCDPLTGACRGCLRHTTGPRCESCAPGFYGNALLPGNCTRCDCSPCGTETCDPQTGRCLCKAGVTGQRCDHCLEGHFGFEQCQGCHPCACGPAAEGSECNPQTGQCHCRPGTTGPQCLECAPGYWGLPEKGCRRCQCPRGH-----CDPHTGRCTCPPGLSGERCDTCSQQHQVPVPGRPGSHGIHCEVCDHCVVLLLDDLERAGALLPSIREQLRGINASSTAWARLHRLNASIADLQSKLRSPLGPHNQTAEQLQTLEQQSISLQQDTERLGSQATGVQDQAGRLLDNTESTLVRAQKLLEIVQAVSRALNELAS---QGFPGNATTPSGEQLRWALAEVERLLWDMRTRDLGAPQAVAEAELAEAQRLMARVQEQLTSFWEENQALATHIRDQLAQYESGLMDLREALNHAVNTTREADELNSRNEERLREALQWKQELSQDNATLKATLQAASLTLAHVSELLQGIDKAKEDLEHLAASLDGAWTPLLKRMQAFS-PASSKVDLVEAAEAHAQKLNQLAINLSGIIQGINQDRFIQRAVEASNAYSSILQAVQAAEDAAGHALRQASRTWEMVVQRGLAAGARQLLANSSALVETILGHQERLG-LAHGRLQAAGTQLRDVRAKKNQLAAQIQEAQAMLAMDTSETS-EKIAHAKAVAAEARDTAAHVQSQLQGMQKNVERWQSQLGGLRGQDLSQAERDASSSVSTLEKTLP-----QLLAKLSHLENRGVHNASLALSANIGRVRKLIAQARSAANKVKVSMKFNGRSGVRLRTPRDLADLAAYTALKFYIQSPVPAPEPGENTGDRFVLYMGSRQATGDYMGVSLRNQKVHWVYRLGEAGPTTLSIDENIGEQFAAVSIDRTLQFGHMSVTVEKHMVHEIKGDTVAPGREGLLNLNPD-DFVFYVGGYP--SNFTPPEPLRFPGYLGCIEMDTLNEEVVSLYNFEQAFKLTTAVDKPCARSKTTGDPWLTDGSYLDGSGFARITFEKQFSN--TKRFEQELRLVSYNGIIFFLKQENQFLCLAVQDGTLVLLYDFGSGLKRADPLQPPQALTAASKAIQVFLLAGARKRVLVRVERATVFSVDQDNELEMADAYYLGGVPPEELPPSLRRLFPSGGSVRGCIKGIKALGKYVDLKRLNTTG-ISFSCTADLLMGRTMTFHGHGFLPLALPDVAPITGEVYSGFGFRGTQDDNLLYYRTSPD--GPYQVSLRGGHVTLQFMNREVETQRVFADGAPHYVAFYSNVTRVWLYVDDQLQPVKSREGTTPMLQ---LQPEEPPRLLLGGLPMSGTFHNFSGCISNVFVQRLRG----------------PQRVFDLHQNMGSVNVSVG------------------------CTPAQLQTSG--------ATAQKVSRRSRQPS------------------------------QDLTCMTP----WLLGTIQDAYQFGGPGPSYLQFVGVSPSHRNRLHLSMLVRPHGASQGLLLYVAPLSSHSPSLVLFLNHGRFVAQTEGPGPQLQAQSRQHSRAGQWHRVSVRWGMQQVQLVVDGSQTWSQKAPHRRVHRAEGPQHYTLFVGGLPAGSYSSKLPVSVG------FSGCMKKLQLDKRPLRAPTRMVGVTPCVSGPLEDGLFFPGSEGAVTLELPKAKMPHVSLELEVRPLAAAGLIFHLGQAHATPYVQLQLLTEQVLLRANDG-AGEFSTWVTYP-KLCDGQWHQVTVIKGRNTLRLEVDTHS-NHTTGRLPETLADSPALLHLG--SPPKSEAAWPEPPAYRGCLRKLLFNGAPVNMTASARIQGAVGMSGCPSGTLAISKQGKALTQRQANPSVFPLRWH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61001-1", "uniprot_id": "LAMA5_MOUSE", "id": "Q61001-1", "name": "Laminin subunit alpha-5", "aln": "MAKRGGQLCAGSAPGALGPRSPAPRPLLLLLAGLALVGEART--PGGDGFSLHPPYFNLAEGARITASATCGEEAPTRSVSRPTEDLYCKLVGGPVAGGDPNQ-TIQGQYCDICTAANSNKAHPVSNAIDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSTDFGHTYQPWQFFASSKRDCLERFGPRTLERITQDDDVICTTEYSRIVPLENGEIVVSLVNGRPGALNFSYSPLLRDFTKATNIRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADVCDAKDPLDPFR-LQCACQHNTCGGSCDRCCPGFNQQPWKPATTDSANECQSCNCHGHAYDCYYDPEVDRRNASQNQDNVYQGGGVCLDCQHHTTGINCERCLPGFFRAPDQPLDSPHVCRPCDCESDFTDGTCEDLTGRCYCRPNFTGELCAACAEGYTDFPHCYPLPSFPHNDTREQVLPAGQIVNCDCNAAGTQGNACRKDPRLGRCVCKPNFRGAHCELCAPGFHG-PSCHPCQCSSPGVANSLCDPESGQCMCRTGFEGDRCDHCALGYFHFPLCQLCGCSPAGTLPEGCD-EAGRCQCRPGFDGPHCDRCLPGYHGYPDCHACACDPRGALDQQCGVGGLCHCRPGYTGATCQECSPGFYGFPSCIPCHCSADGSLHTTCDPTTGQCRCRPRVTGLHCDMCVPGAYNFPYCEAGSCHPAGLAPANP--ALPETQAPCMCRAHVEGPSCDRCKPGYWGLSASNPEGCTRCSCDPRGTLGGVTECQ-GNGQCFCKAHVCGKTCAACKDGFFGLDYADYFGCRSCRCDVGGALGQGCEPKTGACRCRPNTQGPTCSEPAKDHYLPDLHHMRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAHMMAIQPRIVARLNVTSPDLFRLVFRYVNRGSTSVNGQISVREEGKLSSCTNCTEQSQPVAFPPSTEPAFVTVPQRGFGEP--FVLNPGIWALLVEAEG-VLLDYVVLLPSTYYEAALLQHRVTEACTYRPSALHSTENCLVYAHLPLDGFPSAAGTEALCRHDNSLPRPCPTEQLSPSHPPLATCFGSDVDIQLEMAVPQPGQYVLVVEYVGE-DSHQEMGVAVHTPQRAPQQGVLNLHPCPYSSLCRSPARDTQHHLAIFYLDSEASIRLT----AEQAHFFLHSVTLVPVEEFSTEFVEPRVFCVSSHGTFNPSSAACLASRFPKPPQPIILKDCQVLPLPPDLPLTQSQELSPGAPPEGPQPRPPTAVDPNAEPTLLRHPQGTVVFTTQVPTLGRYAFLLHGYQPVHPSFPVEVLINGGR-IWQGHANASFCPHGYGCRTLVLCEGQTMLDVTDNELTVTVRVPEGRWLWLDYVLIVPEDAYSSSYLQEEPLDKSYDFISHCATQGYHISPSSSSPFCRNAATSLSLFYNNGALPCGCHEVGAVSPTCEPFGGQCPCRGHVIGRDCSRCATGYWGFPNCRPCDCG-ARLCDELTGQCICPPRTVPPDCLVCQPQSFGCHPLVGCEECNCSGPGVQELTDPTCDMDSGQCRCRPNVAGRRCDTCAPGFYGYPSCRPCDCHEAGTMASVCDPLTGQCHCKENVQGSRCDQCRVGTFSLDAANPKGCTRCFCFGATERCGNSNLARHEFVDMEGWVLLSSDRQVVPHEHRPEIELLHADLR----SVADTFSELYWQAPPSYLG---------DRVSSYGGTLHYELHSETQRGDIFIPYESRPDVVLQGNQMSIAFLELAYPPPGQVHRGQLQLVEGNFRHLETHNPVSREELMMVLAGLEQLQIRALFSQTSSSVSLRRVVLEVASEAGRGP---PASNVELCMCPANYRGDSCQECAPGYYRDTKGLFLGRCVPCQCHGHSDRCLPGSGICVGCQHNTEGDQCERCRPGFVSSDPSNPASPCVSCPCPLAVPSNNFADGCVLR--NGRTQCLCRPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNMIFSDCDPLTGACRGCLRHTTGPHCERCAPGFYGNALLPGNCTRCDCSPCGTETCDPQSGRCLCKAGVTGQRCDRCLEGYFGFEQCQGCRPCACGPAAKGSECHPQSGQCHCQPGTTGPQCLECAPGYWGLPEKGCRRCQCPRGH-----CDPHTGHCTCPPGLSGERCDTCSQQHQVPVPGKPGGHGIHCEVCDHCVVLLLDDLERAGALLPAIREQLQGINASSAAWARLHRLNASIADLQSKLRSPPGPRYQAAQQLQTLEQQSISLQQDTERLGSQATGVQGQAGQLLDTTESTLGRAQKLLESVRAVGRALNELASRMGQGSPGDALVPSGEQLRWALAEVERLLWDMRTRDLGAQGAVAEAELAEAQRLMARVQEQLTSFWEENQSLATHIRDQLAQYESGLMDLREALNQAVNTTREAEELNSRNQERLKEALQWKQELSQDNATLKATLQAASLILGHVSELLQGIDQAKEDLEHLAASLDGAWTPLLKRMQAFS-PASSKVDLVEAAEAHAQKLNQLAINLSGIILGINQDRFIQRAVEASNAYSSILQAVQAAEDAAGQALRQASRTWEMVVQRGLAAGARQLLANSSALEETILGHQGRLG-LAQGRLQAAGIQLHNVWARKNQLAAQIQEAQAMLAMDTSETS-EKIAHAKAVAAEALSTATHVQSQLQGMQKNVERWQSQLGGLQGQDLSQVERDASSSVSTLEKTLP-----QLLAKLSRLENRGVHNASLALSANIGRVRKLIAQARSAASKVKVSMKFNGRSGVRLRTPRDLADLAAYTALKFHIQSPVPAPEPGKNTGDHFVLYMGSRQATGDYMGVSLRNQKVHWVYRLGKAGPTTLSIDENIGEQFAAVSIDRTLQFGHMSVTVEKQMVHEIKGDTVAPGSEGLLNLHPD-DFVFYVGGYP--SNFTPPEPLRFPGYLGCIEMETLNEEVVSLYNFEQTFMLDTAVDKPCARSKATGDPWLTDGSYLDGSGFARISFEKQFSN--TKRFDQELRLVSYNGIIFFLKQESQFLCLAVQEGTLVLFYDFGSGLKKADPLQPPQALTAASKAIQVFLLAGNRKRVLVRVERATVFSVDQDNMLEMADAYYLGGVPPEQLPLSLRQLFPSGGSVRGCIKGIKALGKYVDLKRLNTTG-ISFGCTADLLVGRTMTFHGHGFLPLALPDVAPITEVVYSGFGFRGTQDNNLLYYRTSPD--GPYQVSLREGHVTLRFMNQEVETQRVFADGAPHYVAFYSNVTGVWLYVDDQLQLVKSHERTTPMLQ---LQPEEPSRLLLGGLPVSGTFHNFSGCISNVFVQRLRG----------------PQRVFDLHQNMGSVNVSVG------------------------CTPAQLIETSR-------ATAQKVSRRSRQPS------------------------------QDLACTTP----WLPGTIQDAYQFGGPLPSYLQFVGISPSHRNRLHLSMLVRPHAASQGLLLSTAPMSGRSPSLVLFLNHGHFVAQTEGPGPRLQVQSRQHSRAGQWHRVSVRWGMQQIQLVVDGSQTWSQKALHHRVPRAERPQPYTLSVGGLPASSYSSKLPVSVG------FSGCLKKLQLDKRPLRTPTQMVGVTPCVSGPLEDGLFFPGSEGVVTLELPKAKMPYVSLELEMRPLAAAGLIFHLGQALATPYMQLKVLTEQVLLQANDG-AGEFSTWVTYP-KLCDGRWHRVAVIMGRDTLRLEVDTQS-NHTTGRLPESLAGSPALLHLG--SLPKSSTARPELPAYRGCLRKLLINGAPVNVTASVQIQGAVGMRGCPSGTLALSKQGKALTQRQAKPSVSPLLWH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15230-1", "uniprot_id": "LAMA5_HUMAN", "id": "O15230-1", "name": "Laminin subunit alpha-5", "aln": "MAKR---LCAGSALCVRGPR--GPAP--LLLVGLALLGAARAREEAGGGFSLHPPYFNLAEGARIAASATCGEEAPARGSPRPTEDLYCKLVGGPVAGGDPNQ-TIRGQYCDICTAANSNKAHPASNAIDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFR-LQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSS-SNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG-PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCD-EAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDP--ALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAQMAPVQPRIVARLNLTSPDLFWLVFRYVNRGAMSVSGRVSVREEGRSATCANCTAQSQPVAFPPSTEPAFITVPQRGFGEP--FVLNPGTWALRVEAEG-VLLDYVVLLPSAYYEAALLQLRVTEACTYRPSAQQSGDNCLLYTHLPLDGFPSAAGLEALCRQDNSLPRPCPTEQLSPSHPPLITCTGSDVDVQLQVAVPQPGRYALVVEYANE-DARQEVGVAVHTPQRAPQQGLLSLHPCLYSTLCRGTARDTQDHLAVFHLDSEASVRLT----AEQARFFLHGVTLVPIEEFSPEFVEPRVSCISSHGAFGPNSAACLPSRFPKPPQPIILRDCQVIPLPPGLPLTHAQDLTPAMSPAGPRPRPPTAVDPDAEPTLLREPQATVVFTTHVPTLGRYAFLLHGYQPAHPTFPVEVLINAGR-VWQGHANASFCPHGYGCRTLVVCEGQALLDVTHSELTVTVRVPKGRWLWLDYVLVVPENVYSFGYLREEPLDKSYDFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCG-ARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQPGTEMLRADLRHVPEAVPEAFPELYWQAPPSYLG---------DRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGA---LASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSR-DDPSAPCVSCPCPLSVPSNNFAEGCVLR--GGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPGGR-----CDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFS-PAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAMLQEQQRLG-LVWAALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETS-KKIAHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLP-----QLLAKLSILENRGVHNASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQG--PEPEPGQGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGEQFAAVSLDRTLQFGHMSVTVERQMIQETKGDTVAPGAEGLLNLRPD-DFVFYVGGYP--STFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLTDGSYLDGTGFARISFDSQIST--TKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVLLYDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLELADAYYLGGVPPDQLPPSLRRLFPTGGSVRGCVKGIKALGKYVDLKRLNTTG-VSAGCTADLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPD--GLCQVSLQQGRVSLQLLRTEVKTQAGFADGAPHYVAFYSNATGVWLYVDDQLQQMKPHRGPPPELQ---PQPEGPPRLLLGGLPESGTIYNFSGCISNVFVQRLLG----------------PQRVFDLQQNLGSVNVSTG------------------------CAPALQAQTPGLGPRGLQATARKASRRSRQPA------------------------------RHPACMLP----PHLRTTRDSYQFGGSLSSHLEFVGILARHRNWPSLSMHVLPR-SSRGLLLFTARLRPGSPSLALFLSNGHFVAQMEGLGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHTLFVGGLPASSHSSKLPVTVG------FSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDG-AGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQS-NHTVGPLLAAAAGAPAPLYLG--GLPEPMAVQPWPPAYCGCMRRLAVNRSPVAMTRSVEVHGAVGASGCPAA--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q00174-1", "uniprot_id": "LAMA_DROME", "id": "Q00174-1", "name": "Laminin subunit alpha", "aln": "-------MGHGVASIG------------ALLVILAIS---------YCQAELTPPYFNLATGRKIYATATCGQDTDG-------PELYCKLVGANTEHDHIDYSVIQGQVCDYCDPTVPERNHPPENAIDGTEAWWQSPPLSRGMKFNEVNLTINFEQEFHVAYLFIRMGNSPRPGLWTLEKSTDYGKTWTPWQHFSDTPADCETYFGKDTYKPITRDDDVICTTEYSKIVPLENGEIPVMLLNERPSSTNYFNSTVLQEWTRATNVRIRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCNGHADTCDVKDPKSPVRILACRCQHHTCGIQCNECCPGFEQKKWRQNTNARPFNCEPCNCHGHSNECKYDEEVNRKGLSLDIHGHYDGGGVCQNCQHNTVGINCNKCKPKYYRPKGKHWNETDVCSPCQCDYFFSTGHCEEETGNCECRAAFQPPSCDSCAYGYYGYPNCR---------------------ECECNLNGTNGYHCEAESGQ-QCPCKINFAGAYCKQCAEGYYGFPECKACECNKIGSITNDCNVTTGECKCLTNFGGDNCERCKHGYFNYPTCSYCDCDNQGTESEICNKQSGQCICREGFGGPRCDQCLPGFYNYPDCKPCNCSSTGSSAITCDNTGKCNCLNNFAGKQCTLCTAGYYSYPDCLPCHCDSHGSQGVSCN-SDGQCLCQPNFDGRQCDSCKEGFYNFPSCEDCNCDPAGVIDKFAGCGSVPVGELCKCKERVTGRICNECKPLYWNLNISNTEGCEICDCWTDGTISALDTCTSKSGQCPCKPHTQGRRCQECRDGTFDLDSASLFGCKDCSCDVGGSWQSVCDKISGQCKCHPRITGLACTQPLTTHFFPTLHQFQYEYEDGSLPSGTQVRYDYDEAAFPGFSSKGYVVFNAIQNDVRNEVNVFKSSLYRIVLRYVNPNAENVTATISVTSDN-----PLEVDQHVKVLLQPTSEPQFVTVAGPLGVKPSAIVLDPGRYVFTTKANKNVMLDYFVLLPAAYYEAGILTRHISNPCELGNMELCRHYKYASVEVFSPAATPFVIGENSKPTNPVETYTDPEHLQIVSHVGDIPVLSGSQNELHYIVDVPRSGRYIFVIDYISDRNFPDSYYINLKLKDNPDSETSVLLYPCLYSTICRTSVNEDGMEKSFYINKEDLQPVIISADIEDGSRFPIISVTAIPVDQWSIDYINPSPVCVIHD-------QQCATPKFRSVPD----------SKKIEFETDHEDRIATNKPPYASLDERVKLVHLDSQ----NEATIVIESKVDATKPNLFVILVKYYQPSHPKYQVYYTLTAGKNQYDGKFDIQHCPSSSGCRGVIRPAGEGSFEIDD-EFKFTITTDRSQSVWLDYLVVVPLKQYNDDLLVEETFDQTKEFIQNCGHDHFHITHN-ASDFCKKSVFSLTADYNSGALPCNCDYAGSTSFECHPFGGQCQCKPNVIERTCGACRSRYYGFPDCKPCKCPNSAMCEPTTGECMCPPNVIGDLCEKCAPNTYGFHQVIGCEECACNPMGIANGNS-QCDLFNGTCECRQNIEGRACDVCSNGYFNFPHCEQCSCHKPGTELEVCDKIDGACFCKKNVVGRDCDQCVDGTYNLQESNPDGCTTCFCFGKTSRCDSAYLRVYNVSLLKHVSITTPEFHEESIKFDMWPVPADEILLNETTLKADFTLREVNDERPAYFGVLDYLLNQNNHISAYGGDLAYTLHFTSG---FDGKYIVAPDVILFSEHNALVHTSYEQPSRNEPFTNRVNIVESNFQTISGK-PVSRADFMMVLRDLKVIFIRANYWEQTLVTHLSDVYLTLADEDADGTGEYQFLAVERCSCPPGYSGHSCEDCAPGYYRDPSGPYGGYCIPCECNGHSETCDCATGICSKCQHGTEGDHCERCVSGYYGNATNGTPGDCMICACPLPFDSNNFATSCEISESGDQIHCECKPGYTGPRCESCANGFYGEPESIGQVCKPCECSGNINP-EDQGSCDTRTGECLRCLNNTFGAACNLCAPGFYGDAIKLKNCQSCDCDDLGTQTCDPFVGVCTCHENVIGDRCDRCKPDHYGFESGVGCRACDCGAASNSTQCDPHTGHCACKSGVTGRQCDRCAVDHWKYEKDGCTPCNCNQGYSRGFGCNPNTGKCQCLPGVIGDRCDACPNRWVLIKDEG-------CQECNNCHHALLDVTDRMRYQIDSVLEDFNSVTLAFFTSQKLNYYDQLADELEPKVKLLD----PNSVDLSPSKKANSELESDAKSYAKQVNQTLANAFDIRERSSTTLGNITVAYDEAVKSADQAKEAIAS-VEALSKNLEAAASTKIDAALEQAQHILGQING--TSIELTPNEQVLEKARKLYEEVNTLVLPIKAQNKSLN-ALKNDIGEFSDHLEDLFNWSEASQAKSADVERRNVANQKAFDNSK--FDTVSEQKLQAEKNIKDAGNFLINGDLTLNQINQKLDNLRDALNELNSFNKNVDEELPVREDQHKEADALTDQAEQKAAELAIKAQDLAAQYTDMTAS--AEPAIKAATAYSGIVEAVEAAQKLSQDAISAAGN--ATDKTDGIEERAHLADTGSTDLLQRARQSLQKVQDDLEPRLNASAGKVQKISAVNNATEHQLKDINKLIDQLPAESQRDMWKNSNANASDALEILKNVLEILEPVSVQTPKELEKAHGIN-RDLDLTNKDVSQANKQLDDVEGSVSKLNELAEDIEEQQHRVGSQSRQLGQEIENLKAQVEAARQLANSIKVGVNFKPSTILELKTPEKTKLLATRTNLSTYFRTTEPSGFLLYLGND-----NKTAQKNNDFVAVEIVNGYPILTIDLGNGPERITSDKYVADGRWYQAVVDRMGPNAKLTIREELPNGDVVEHSKSGYLEGSQNILHVDKNSRLFVGGYPGISDFNAPPDLTTNSFSGDIEDLKIGDESVGLWNFVYGDDNDQGARE---RDVLLEKKKPVTGLRFKGNGYVQLNATSNLKSRSSIQFSFKADKDTSNGLLFFYGRDKHYMSIEMIDGAIFFNISLGEGGGVQSGSQDRYNDNQWHKVQAERENRNGLLKVDDIVISRTNAPLEADLELPKLRRLYFGGHPR-----RLNTSISLQPNFDGCIDNVVINQGVVDLTEYVTGGGVEEGCSAKFSTVVSYAPHEYGFLRMNN---VSSDNNLHVVLHFKTTQPNGVLFYAANHDQSSTIGLSLQDGLLKLNSMGSQLVIDDRILNDGEDHVVTVQHTQGELRLTVDDVDNKRLGSPQPLILEGGDIFFAGLPDNYRTPRNALASLAYFVGCISDVTVNEEIINFANSAEKKNGNINGCPPHVLAYEPSLVPSYYPSGDNEVESPWSNADTLPPLKPDIESTLPPTTPTTTTTTTTTTTSTTTTSTTTTTTTPSPIVIDEEKEIEAKTPQKILTTRPPAKLNLPSDERCKLPEQPNFDVDFTEAGYRFYGLREQRLQINSLPVKVRRHHDIGISFRTE-RPNGLLIYAGSKQRDDFIAVYLLDGRVTYEIRVGAQLQAKITTEAELNDGTWHTVEVVRTQRKVSLLIDKLEQPGSVDLNAERSAPVLAVELPIYLGGVNKFLESEVKNLTDFKTEVPYFNGCLKNIKFDAMDLETPPEEFGVVPCS-EQVERGLFFNNQKAFVKIFDHFDVGTEMKISFDFRPRDPNGLLFSVHGKNSYAILELVDNTLYFTVKTDLKNIVSTNYKLPNNESFCDGKTRNVQAIKSKFVINIAVDFISSNPGVGNEGSVITRTNRPLFLGGHVAFQRAPGIKTKKSFKGCISKVEVNQRMINITPNMVVG-DIWQGYCPLN--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * **. **: .* ******* * :* *:****::: :*******. . .. : .*:** ** * .: .:: ** .******* ********** ::****:*::: * *****::*::.*****.**.**:* *:*:*: ***.*:.: ** ** * : **:** .*******:********* * *:* **.: *: *.:*:::*:***:*:*:***:.******. * :********:************:*:****.**.*** .*.* * * ***:*** *:.*****:*: *: * . :*:.***:**: :* ** **:*: * . .. *:***** :***:*.*:**::* * ::*. .: :...** *:*: *: * **: **.* **. * * ** *: .:* * :*:*. **:* *. :. :* ** ** * :*: ** *::* * *:.*:*.. * . *: :*:* * ..* * *::* ***::* *. *.*. ** .: *: ::*:* *: * **:**:* **::.:*:*:.* *.. *: *. * *.* .::* * *:.*::.:*.*:****.:.** .:*: *** *:*.. * :** * * **** ** .*.***: . . . * *: :* * *:.*** :*.*. **.*** *.* **:..: * .*** **.*. *: * *:** *.** *. :**:.* **:**: . *: :* *:*:*. * :*::* *::* **::: * *:.: *.* **:.:: * .** :**. : .:* : .:*: ...*: :*:**** .: .*.. :** .:. . . * * : *::** *:**. :* :**:** :.: .:*: *:***.****::****.:* ::::.* : :. . * . * :: : . *: . : . **: ::: : **:.*:* :*::* .: :. : :: :.. .: : *:** **::** ...: . :.: ..: . : : ::* : .** :*::::* ::::* *: . * ..:* . *: . : : : ::. .* .. . . *. ::: ... .: ...... . :.:*:: *** **.: * : .*: ::*: : ..** . *** :: *: ::: . *: .*: . ..: :****:::** . *. . * **.:*:: :**.:*. : :**: . :* **:::. **: **.** **.*. .*:.. *.****** *: :** * *. * : *:***:*:**.* : :*: **:*:***..: * * *:::* * ::***** *. *: : .. ** .* *.** *: ** **.*: *:..:* *. *.**:.** *** : * *.**:** * **** **:.*: :**.*** ***** *.** .: :. :: : :.: : . : * .: . : *:*:* :::*:*** * * ** : . ***:* .:: ::.. . *. .. . .::::**.**: . : .*** ::**** .*: : *** : : : . * * * :*. . *. ** * **..* *.**::****:*** .* : * *:**:*:***: * .:* * ***.*** :**** .*: .. ..... *: *.***.. ***** .* : ..: :* *:***:*. ** ** **:*:* :*. *:**:**** :* ..**. ** * **.:* *. *: *******:*: ** *** **::*** * * *: .* * ***:* .::**: **:.* **.*::.::*.*::*:* *:.*. * ** .** .:* :.** *:* * *:*:**:* * **: *:***:*.:: : *: *::* *** :* : :: *::..:. : : :*: : :*:.::: : :*. :: . .* .*:. . *. . :* : :.:** . .* : . : ..:. :: :* :.:::* ::. . : * * *::* .*: : .: :*::* :: :.:.. * ** : : : : :.:. * *:: : :: : :*.:: : .:: * * *: ::: ::*. .*:. . : :.: . . . *.: ** :* :* * :*:. .:. . : *::*:.*** *::**:**:. : .*: *.. *: *: :.*: * : :: *:.: :::.: * :: ::: : :: . *:. . :::* *::* . .* . *: :. :. : : *:. :**. . *.. : . *:.. : **: ::: * . * *. .* .:: : ** *..:** ::*: : :.*:**.. **: * *. ::: * * : * ..*::.*.: : . **:. * . . :: . :** .:::: * . : .. . . *. * : ::***** * *..* * .: * ** .:.:* *.*:** .. . *. . . * :.*.*:.::. .::.. : :*. : : .*::** ::.:::.: : :*::.: .:* * * . *. . :* * * .:: * * *:** * *. :. .. **:..: ***.. * * :. .*:*.: : : * :*** : .. :: : *: :* . :*:* :. * . :**: * :.*. : :: : : :.. .:*. .:. . *::: : . *: . .:: * ****:* *:. * :*: . .: . . * .*: : :*: ..: : *: . * * . .*:* * . *:: .: *. :.: . .. ..***: .. . . :*. * : : :. . . * ** *.* .:: *: * . .. : . . . .: :**: *. :: *.**:*.:::. * :*.. **.** :* **** .. . :.: . : :.::.** **:* : : . ::* . :::: . . :. :***: :.: .: . .:.: ** * * .* : : *.** : . :: **: :: .* : :* . : : ** ", "identical_positions": 1021, "similar_positions": 1189, "identity": "26.38%" }, { "cls_id": "homologset.agr.RGD:621024", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63326-1", "uniprot_id": "RS10_RAT", "id": "P63326-1", "name": "Small ribosomal subunit protein eS10", "aln": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRR-SRPETGRPRPK-GPEGERPARFTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63325-1", "uniprot_id": "RS10_MOUSE", "id": "P63325-1", "name": "Small ribosomal subunit protein eS10", "aln": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRR-SRPETGRPRPK-GPEGERPARFTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46783-1", "uniprot_id": "RS10_HUMAN", "id": "P46783-1", "name": "Small ribosomal subunit protein eS10", "aln": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRR-SRPETGRPRPK-GLEGERPARLTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VB14-1", "uniprot_id": "RS10A_DROME", "id": "Q9VB14-1", "name": "Small ribosomal subunit protein eS10A", "aln": "MFIPKANRVAIYEYLFKEGVLVAKKDSPIQKHSELDK--IPNLQVIKVMQSLNSRGWVKEQFAWRHFYWLLTNEGIEELRRYLHLPPEIVPSTLTQTTRSNAVRPRGGPGGPGGGFGGASKTDDDRSNYRRGPGAYGMDKKGDVGAGTG-RVEYRGGFGRASRYDN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWG3-1", "uniprot_id": "RS10B_DROME", "id": "Q9VWG3-1", "name": "Small ribosomal subunit protein eS10B", "aln": "MFMPKAHRVAIYEYLFKEGVIVAKKDFHAQKHPELES--IPNLHVIKAMQSLHSRGLVKEQFAWRHYYWYLTNEGIEELRSYLHLPPEIVPSTLKRPARSETVRPRPAVGGPRG-PGDASKTGEDRSAYRRAPGGSGVDKKGDVGPGAG-EVEFRGGFGRGSRN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46784-1", "uniprot_id": "RS10B_YEAST", "id": "P46784-1", "name": "Small ribosomal subunit protein eS10B", "aln": "MLMPKQERNKIHQYLFQEGVVVAKKDFNQAKHEEIDT---KNLYVIKALQSLTSKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLPEHIVPGTYIQ-ERNPSQRPQRR--------------------Y--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08745-1", "uniprot_id": "RS10A_YEAST", "id": "Q08745-1", "name": "Small ribosomal subunit protein eS10A", "aln": "MLMPKEDRNKIHQYLFQEGVVVAKKDFNQAKHEEIDT---KNLYVIKALQSLTSKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLPEHIVPGTYIQ-ERNPTQRPQRR--------------------Y--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::** .* *:: **:***:***** ** *: ** *:*.:*** *:* ** **:*:::*: **:**:: ** **:** .***.* : * : **: * ", "identical_positions": 51, "similar_positions": 26, "identity": "30.54%" }, { "cls_id": "homologset.agr.RGD:621025", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3R3-1", "uniprot_id": "PLCD4_MOUSE", "id": "Q8K3R3-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "aln": "---------------------------------------------------------------------------------------MTSQIQDLLATDQDL----LLMQEGTMMRKVRTKSWKKLRYFRLQNDGMTVWHGSQPESMPKPTFSISDVERIRKGQDSELLRYLVEEFPLEQGFTVVFHGRRPNLDLVANSVEEAQIWMRGLQLLVDLVASMDHQEQMD--------QMLNEWFQQADRNQDGRMSFREAQRLLLLMNVEMDEEYAFSLFQEADVTQSDDLGSEEFVQFYKALTKRTEIEEIFEDFSSDKQ-KLTLLEFVDFLRKEQKEKDHAPDLALELIDRYEPSENGRLLHVLSKDGFLKYLCSKDGNIFNSDCLPIYQDMT-QPLSHYYINSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDTWDGPDGEPVVYHGHTLTSRILFKDVLATLAQYAFQSSDYPLILSLENHCTWEQQRTMAHHLTEILGEQLLRNTLEGLLVDSMPSPEQLRGKILVKGKKLRTIEVDKEEEEEEEEEELEKDEGPDLDPASPELDTQPQPETQGQAAGNKKERKKKVMKCPMSCLLICGHVMAQAPSSIPESILLSKQFLLLSSTTIMCPDLSALVVYLRTVPFCSFTHSKENYHIYDISSFSESKAKNLIKEAGN--EFVQHNARQLCRVYPSGLRTDSSNFNPQEHWNVGCQMVAMNMQTAGSAMDICDGLFRQNGG-------SGYVLKPEFLRDTQSSFNPERPISLYKAQ-----ILVVQVISGQQLPKVDKTKET-TVVDPLVKVELYG-------------VPEDTKEQETSHVENNGINPYWGETFYFRLQVPELAMLRFVVKDYSRKSRNNFIGQYTLPWTCMKQGYRHVSLLSRDGTSLNPASIFVYTCMQEDLDMDEP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62711-1", "uniprot_id": "PLCD4_RAT", "id": "Q62711-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "aln": "---------------------------------------------------------------------------------------MASQIQKLLTTNQDL----LLMQKGTMMRKVRTKSWKKLRYFRLQDDGMTVWHGRHLESISKPTFSISDVERIRKGQDSELLRYLVEEFPLEQGFTIVFNGRRPNLDLVANSVEEAQTWMRGLQLLVDLVARMNYQEQLD--------QMLREWFQQADRNQDSRMSFREAQRLLLLMNVEMDEEYAFSLFQEADVSQSNTLDSEEFVQFYKALTKRTEIEELFENFSSDKQ-KLTLLEFVDFLREEQKESDHSSDLALKLIDRYEPSENGRLLRVLSKDGFLSYLCSADGNIFNPDCLPIYQDMT-QPLSHYYINSSHNTYLLGDQFCGQSSVEGYIRALKRGCRCVEVDTWDGPDGEPVVYHGRTLTSRILFKDVLATLAQYAFQSSDYPLILSLDNHCTWEQQKTMAHHLIAILGEQLLSTTLEEQLIDIMPSPEQLRGKILVKGKKLRTIEV---VESDKEEEELEKDEGSDLDPASAELDMQSQPESQEQASGNKSKNKK--------------------------------KFLLQSSTTILCPDLSALVVYLRTAPFCSFTHSKENYHIYDISSFSESKAKNLIREAGN--EFVQHNARQLCRVYPSGLRTDSSNYNPQEHWNVGCQMVAMNMQTAGSAMDICDGLFRQNGG-------SGYVLKPEFLRDTQSSFNPMKPVSLYKAQ-----ILVVQVISGQRLPKVDKTKET-TVVDPLVRVELYG-------------VPEDTKQQETSYVENNGINPYWGETFYFQIQVPELAMLRFVVKDYSRTSRNNFIGQYTLPWTCMKHGYRHVSLLSKDGTSLHPASIFVYTCMQEDLDMDEP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BRC7-1", "uniprot_id": "PLCD4_HUMAN", "id": "Q9BRC7-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "aln": "---------------------------------------------------------------------------------------MASLLQDQLTTDQDL----LLMQEGMPMRKVRSKSWKKLRYFRLQNDGMTVWHARQARGSAKPSFSISDVETIRNGHDSELLRSLAEELPLEQGFTIVFHGRRSNLDLMANSVEEAQIWMRGLQLLVDLVTSMDHQERLD--------QWLSDWFQRGDKNQDGKMSFQEVQRLLHLMNVEMDQEYAFSLFQAADTSQSGTLEGEEFVQFYKALTKRAEVQELFESFSADGQ-KLTLLEFLDFLQEEQKERDCTSELALELIDRYEPSDSGKLRHVLSMDGFLSYLCSKDGDIFNPACLPIYQDMT-QPLNHYFICSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDVWDGPSGEPVVYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETHCSWEQQQTMARHLTEILGEQLLSTTLDGVLPTQLPSPEELRRKILVKGKKL-TLEEDLEYEEEEAEPELEESE------LALESQFETEPEPQEQNLQNKDKKKK--------------------------------------SKPILCPALSSLVIYLKSVSFRSFTHSKEHYHFYEISSFSETKAKRLIKEAGN--EFVQHNTWQLSRVYPSGLRTDSSNYNPQELWNAGCQMVAMNMQTAGLEMDICDGHFRQNGG-------CGYVLKPDFLRDIQSSFHPEKPISPFKAQ-----TLLIQVISGQQLPKVDKTKEG-SIVDPLVKVQIFG-------------VRLDTARQETNYVENNGFNPYWGQTLCFRVLVPELAMLRFVVMDYDWKSRNDFIGQYTLPWTCMQQGYRHIHLLSKDGISLRPASIFVYICIQEGLEGDES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P32383-1", "uniprot_id": "PLC1_YEAST", "id": "P32383-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1", "aln": "MTESAIDDQRFNLTKELQRHSCRDQGKITQKDDALDFISYSSFQSSFNTDQKSANNGSTVRRSIRSIFRRAAELPRVHMGPLTYSHGINELVNKKLRKDCDLSTLCRVLQRGIRMIRMTRRRRKFYEFKLINNNGQIIWKDGSKYLELDSVKDIRIGDTASTYQEEVDPKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFNTFLSCICGLVKLRRELMESILLPDNSQFARIHWQITVSEKEEDEKKDTLSFADVKKLCDKFHIYVSTGQLLEFFQLADINHNGLLNYFEFEKFIKILKNRKEVNMIWSKFTKPPHSHLSFENFFQFLITEQHEQVDRQTAWSYFIKYREPT-----QLTMGQDGFTKFLKEQ------PYLVEVKEELYSKPLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDIWDGENG-PVVCHG-FLTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLIMREVLAEQLY---FVGTRTDKLPSPRELKHKILLKSKKTSEATRGLSVNEPFPSSFSSSYESANEQELRMKDDSTNSSSATNSSSMQRIKRIG------------------------------------LKKHADIINDVSNISG-IHGIKFRNFSLP-ESKTIAHCFSLNERKVEYMIKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNWQTNDIGQQLNLAMFQILDHQPDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFENGSDPVTVKIRILSTQLLPRLNDTSPSRNNTNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKSSQGNGFNPIWDAEVSITLKDTDLTFIKFMVIS-----EETQIASVCLKLNYLRMGYRHIPLFNMEGEQYIFCTLFIHTQIL--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ::. * .: ** ::*.* * :: : * .: ::::* :*: .. .* : . ::. : * .: * .: . .: *.::* . : : :: : **.* : . : : :: : ::.. :** :.::* ::: :. :.:** ** .:.. * ** :* * *.:* *:: ::..*: : :*:: :*.:** **:* :*. **: .:. *** .:* . . : : ::: :**.**:* *******:*.*:. .******:.*::******:* *** .* *** ** *** * :* *: .: :*** :* **:*:**: :*. ::*: : : :*.*** : :***.:*: ***:*.** :. . .. * : : .... . :: :. . . : :* : :: * .*: . * : . *:.* *.: :*:: .: :** * **** ** .***:** *:.* **** * ** . :: . *: . .******. * :. : : . : : ::::* * **:::.*. . .:.:*:*::. . .: . .*. :.**:** *. . : : .:*::::*:* . .: *.. * . :: ****: *:. :* . .::*:: : ", "identical_positions": 180, "similar_positions": 261, "identity": "19.23%" }, { "cls_id": "homologset.agr.RGD:621026", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62281-1", "uniprot_id": "RS11_MOUSE", "id": "P62281-1", "name": "Small ribosomal subunit protein uS17", "aln": "---MADIQTERAYQKQPTIFQNKKRVLLGE-TGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAG-TKKQFQKF--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62282-1", "uniprot_id": "RS11_RAT", "id": "P62282-1", "name": "Small ribosomal subunit protein uS17", "aln": "---MADIQTERAYQKQPTIFQNKKRVLLGE-TGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAG-TKKQFQKF--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62280-1", "uniprot_id": "RS11_HUMAN", "id": "P62280-1", "name": "Small ribosomal subunit protein uS17", "aln": "---MADIQTERAYQKQPTIFQNKKRVLLGE-TGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAG-TKKQFQKF--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QE68-1", "uniprot_id": "A0A8M9QE68_DANRE", "id": "A0A8M9QE68-1", "name": "Small ribosomal subunit protein uS17", "aln": "---MAVTQNVRDYQKQPTIFQNKKGVLAVEGSGKEKLPRYHRNVGLGFKNPREAIDGTYIDKKCPFTGNVSIRGWILSGVVTKMKMQRTIVIRRDNLHYIRKYNRFEKRHKNMSVHLSPCFRDVTVGDIVTVGEWQTLSKTVRFNVLKVTKAEA-VPEVLELLFLQYGSPVLLKKKT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E9B6-1", "uniprot_id": "RS11_DROME", "id": "Q0E9B6-1", "name": "Small ribosomal subunit protein uS17", "aln": "---MAD-QNERAFQKQFGVNLNRKVKPGIT---KKKLLRRSRDVGLGFKTPREAIDGTYIDKKCPWTGDVRIRGRILTGVVRKAKMQRTIVIRRDYLHFVRKYSRFEKRHRNMSVHCSPVFRDVEHGDIVTIGECRPLSKTVRFNVLKVSKGQG-AKKSFKKY--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX47-1", "uniprot_id": "RS11A_YEAST", "id": "P0CX47-1", "name": "Small ribosomal subunit protein uS17A", "aln": "MSTELTVQSERAFQKQPHIFNNPKVKTSKR------TKRWYKNAGLGFKTPKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFR-VQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX48-1", "uniprot_id": "RS11B_YEAST", "id": "P0CX48-1", "name": "Small ribosomal subunit protein uS17B", "aln": "MSTELTVQSERAFQKQPHIFNNPKVKTSKR------TKRWYKNAGLGFKTPKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFR-VQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF--------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * :*** : * * * :: *****.*: **:*:*******:** * *** **:*.* . **:******* **:: **.*:****:*:.** ** ** * *****:*: :.:********:**: . . . : : ", "identical_positions": 76, "similar_positions": 33, "identity": "42.94%" }, { "cls_id": "homologset.agr.RGD:621027", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62277-1", "uniprot_id": "RS13_HUMAN", "id": "P62277-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62301-1", "uniprot_id": "RS13_MOUSE", "id": "P62301-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62278-1", "uniprot_id": "RS13_RAT", "id": "P62278-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03334-1", "uniprot_id": "RS13_DROME", "id": "Q03334-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHAPGKGISQSALPYRRTVPSWLKLNADDVKEQIKKLGKKGLTPSKIGIILRDSHGVAQVRFVNGNKILRIMKSVGLKPDIPEDLYHMIKKAVAIRKHLERNRKDKDGKFRLILVESRIHRLARYYKTKSVLPPNWKYESSTASALVA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05756-1", "uniprot_id": "RS13_YEAST", "id": "P05756-1", "name": "Small ribosomal subunit protein uS15", "aln": "MGRMHSAGKGISSSAIPYSRNAPAWFKLSSESVIEQIVKYARKGLTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYLIKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTVAVLPPNWKYESATASALVN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:.***:*.**:** *..*:*:**.::.* *** * .:******:**::***:***:*.*.:.****:**:** ** *::*****::*****::************.******:***********:* **********:****** ", "identical_positions": 106, "similar_positions": 36, "identity": "70.2%" }, { "cls_id": "homologset.agr.RGD:621028", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61803-1", "uniprot_id": "DAD1_HUMAN", "id": "P61803-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "aln": "-----------MSASVVSVISRFLEEYLSST---------PQRLKLLDAYLLYILLTGALQFGYCLLVG-TFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61804-1", "uniprot_id": "DAD1_MOUSE", "id": "P61804-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "aln": "-----------MSASVVSVISRFLEEYLSST---------PQRLKLLDAYLLYILLTGALQFGYCLLVG-TFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61805-1", "uniprot_id": "DAD1_RAT", "id": "P61805-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "aln": "-----------MSASVVSVISRFLEEYLSST---------PQRLKLLDAYLLYILLTGALQFGYCLLVG-TFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VLM5-1", "uniprot_id": "DAD1_DROME", "id": "Q9VLM5-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "aln": "------------MVELSSVISKFYNDYVQNT---------PKKLKLVDIYLGYILLTGIIQFVYCCLVG-TFPFNSFLSGFISTVSCFVLAVCLRLQANPQNKSVFAGISPERGFADFIFAHVILHLVVMNFIG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46964-1", "uniprot_id": "OST2_YEAST", "id": "P46964-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2", "aln": "MAKAPKANTPKVTSTSSAVLTDFQETFKTSKRAYFAQIEKYPKLKLIDTFCFFLVLLGVIQCTFIILIRDNFPFNAFLAGFIICVGQFVLLMSLRLQLCN----SFPGISKNRAFAEFIVASLILHFVCLHFIN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:: * : : .. :***:* : :::* * :* : *: .****:**:*** *. *:* :.**:* * *** :*.**:*:.* ***:* ::*:.", "identical_positions": 39, "similar_positions": 34, "identity": "29.1%" }, { "cls_id": "homologset.agr.RGD:621029", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q924U0-1", "uniprot_id": "LT4R2_RAT", "id": "Q924U0-1", "name": "Leukotriene B4 receptor 2", "aln": "-----------------------------------MSVCYRPPGNETLLSWKGSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPTAGRPLAATLVLHLALADGAVLLLTPLFVAFLSRQAWPLGQVGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLGVWLAALVLAVPAAVYRHLWGDR------VCQLCHPSAVHAAAHLSLETLTAFVLPFGTVLGCYGVTLARLRGARWGSGRQGTRVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPP-EGPLARLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEA------RVGSRSREGTMELRTTPRLKVVGQGRGYGDPGGG--GRMEKDSQEW--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJL9-1", "uniprot_id": "LT4R2_MOUSE", "id": "Q9JJL9-1", "name": "Leukotriene B4 receptor 2", "aln": "-----------------------------------MSVCYRPPGNETLLSWKGSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPTAGRPLAATLVLHLALADGAVLLLTPLFVAFLSQEAWPLGQVGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLGVWLAALVLAVPAAVYRHLWGGR------VCQLCHPSPVHAAAHLSLETLTAFVLPFGTVLGCYGVTLARLRGARWGSGRQGTRVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPP-EGPLARLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEA------RGGSRSREGTMELRTTPKLKVMGQGRGNGDPGGGDGGKTEKDSQEW--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPC1-1", "uniprot_id": "LT4R2_HUMAN", "id": "Q9NPC1-1", "name": "Leukotriene B4 receptor 2", "aln": "-----------------------------------MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDR------VCQLCHPSPVHAAAHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPP-EGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEA------RGGGRSREGTMELRTTPQLKVVGQGRGNGDPGGG----MEKDGPEWDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1F9-1", "uniprot_id": "A0A8M6Z1F9_DANRE", "id": "A0A8M6Z1F9-1", "name": "", "aln": "MALNLLSPSAFLEIAPSSIPMALQSPSFYTSTLHPTNLSNNTSGRGSIVDNKGGAITGAAILSLVFLLGVPGNVFIMWSILAR--ARRRSITTLLILNLAFADGFLMLLTPFFMVYLVQRSWVFSLALCKVLYYLCCANMYASIFMIMLMSLHRLVAIVWPKRVGAKTERKMLTRVLVGLWVLALGLSAPVLAFRNILSDSKKPEKFVCDCIHPETQYEVMQYSMETLLGFLLPYGVIIGSYTCILRRIRKTRF---RRRIRSEKLILVIVVTFGLFWLPYHIINMVQVTAALLPEGSAAKHRLQEIRANMRALTSTVAFVSSCINPVLYTFAGKSYIRREGLAFMARLFEGTALESTRKIRRSNQNSRERDKETDEGDSIKDKDSDSINTINANSVIKVAPQKNGK---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. ...*. :::. * . **:*:* *. ***:*** *::**: . : *.::: *:*:**:*** ::****:*:.:* :.:* :. . **.:**:*. .****::: *:**:* :*:. * . . : *:*:.:*: ** *:.*. .:*:: . **: **.. : . : *:*** .*:**:* ::*.* * *:* :*: *: * :*: .**::***:* *** :*::*..*** * ... :* ** *:::**.**.:*****.*:. . : * * *::*****:. * . .*** * :* ... ... :.. : ", "identical_positions": 118, "similar_positions": 129, "identity": "28.78%" }, { "cls_id": "homologset.agr.RGD:621030", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64611-1", "uniprot_id": "CSAD_RAT", "id": "Q64611-1", "name": "Cysteine sulfinic acid decarboxylase", "aln": "MADSKPLRTLDGDPVAVEALLRDVFGIVVDEAIRKGTNASEKVCEWKEPEELKQLLDLELQSQGESRERILERCRAVIHYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLKKLRALVGWNTGDGVFCPGGSISNMYAINLARFQRYPDCKQRGLRALPPLALFTSKECHYSITKGAAFLGLGTDSVRVVKADERGKMIPEDLERQISLAEAEGSVPFLVSATSGTTVLGAFDPLDAIADVCQRHGLWLHVDAAWGGSVLLSRTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLRDTSNLLKRCHGSQASYLFQQDKFYNVALDTGDKVVQCGRRVDCLKLWLMWKAQGGQGLEWRIDQAFALTRYLVEEIKKREGFELVMEPEFVNVCFWFVPPSLRGKKESPDYSQRLSQVAPVLKERMVKKGTMMIGYQPHGTRANFFRMVVANPILVQADIDFLLGELERLGQDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBE0-1", "uniprot_id": "CSAD_MOUSE", "id": "Q9DBE0-1", "name": "Cysteine sulfinic acid decarboxylase", "aln": "MADSKPLRTLDGDPVAVEALLQDVFGIVVDEAILKGTSASEKVCEWKEPEELKQLLDLELQSQGESREQILERCRTVIHYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLKKLRALVGWNSGDGVFCPGGSISNMYAMNLARFQRYPDCKQRGLRALPPLALFTSKECHYSITKGAAFLGLGTDSVRVVKADERGRMIPEDLERQIILAEAEGSVPFLVSATSGTTVLGAFDPLDAIADVCQRHGLWFHVDAAWGGSVLLSRTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLRDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGGQGLERRIDQAFALTRYLVEEIKKREGFELVMEPEFVNVCFWFVPPSLRGKKESPDYSQRLSQVAPVLKERMVKKGTMMIGYQPHGTRANFFRMVVANPILAQADIDFLLGELELLGQDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y600-1", "uniprot_id": "CSAD_HUMAN", "id": "Q9Y600-1", "name": "Cysteine sulfinic acid decarboxylase", "aln": "MADSEALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLRKLRALVGWSSGDGIFCPGGSISNMYAVNLARYQRYPDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRVVKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCFWFVPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSALTCADMDFLLNELERLGQDL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:.* :* **********: ***:****** ***..*:*******************:*****:::******:**:*****************************************************:********.:***:************:****:************:**************** **********************:*:******** :*****:********************:************:*************:**********************************:************************:*****************************.**** ******.*:******:*****************************:***** :***:***********:*:***********.****:****. *. **:****.*** *****", "identical_positions": 437, "similar_positions": 45, "identity": "88.64%" }, { "cls_id": "homologset.agr.RGD:621031", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62249-1", "uniprot_id": "RS16_HUMAN", "id": "P62249-1", "name": "Small ribosomal subunit protein uS9", "aln": "MPSKG--PLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62250-1", "uniprot_id": "RS16_RAT", "id": "P62250-1", "name": "Small ribosomal subunit protein uS9", "aln": "MPSKG--PLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14131-1", "uniprot_id": "RS16_MOUSE", "id": "P14131-1", "name": "Small ribosomal subunit protein uS9", "aln": "MPSKG--PLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9W237-1", "uniprot_id": "RS16_DROME", "id": "Q9W237-1", "name": "Small ribosomal subunit protein uS9", "aln": "MQQKRREPVQAVQVFGRKKTATAVAYCKRGNGLLKVNGRPLEQIEPKVLQYKLQEPLLLLGKEKFAGVDIRVRVSGGGHVAQIYAIRQAISKALVAFYQKYVDEASKKEIKDILVQYDRTLLVGDPRRCEPKKFGGPGARARYQKSYR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX52-1", "uniprot_id": "RS16B_YEAST", "id": "P0CX52-1", "name": "Small ribosomal subunit protein uS9B", "aln": "MSAVP-----SVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVEPEILRFKVYEPLLLVGLDKFSNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX51-1", "uniprot_id": "RS16A_YEAST", "id": "P0CX51-1", "name": "Small ribosomal subunit protein uS9A", "aln": "MSAVP-----SVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVEPEILRFKVYEPLLLVGLDKFSNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :**.**:**:*****: * *:**:**** *: :**. *::*: **:**:* ::*:.:******.*****:*:*****:*:*.***::****** **:*:*. : .******:.*.** *.***** ***:*:*****", "identical_positions": 87, "similar_positions": 39, "identity": "58.78%" }, { "cls_id": "homologset.agr.RGD:621032", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62227-1", "uniprot_id": "NR0B2_MOUSE", "id": "Q62227-1", "name": "Nuclear receptor subfamily 0 group B member 2", "aln": "MSSGQSGVCPCQGSAGRPTILYALLSPSPRTRPVAPASHSHCLCQQQRPVRLCAPHRTCREALDVLAKTVAFLRNLPSFCHLPHEDQRRLLECCWGPLFLLGLAQDAVTFEVAEAPVPSILKKILLEEASSGTQGAQPSDRPQPSLAAVQWLQRCLESFWSLELGPKEYAYLKGTILFN--PDVPGLRASCHIAHLQQE-AHWALCEVLEPWYPASQGRLARILLMASTLKNIPGTLLVDLFFRPIMGDVDITELLEDMLLLR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97947-1", "uniprot_id": "NR0B2_RAT", "id": "P97947-1", "name": "Nuclear receptor subfamily 0 group B member 2", "aln": "MSSSQSGVCPCQGSASHPTILYTLLSPGPRTRPMAPASRSHCLCQQHRPVRLCAPHRTCREALDVLGKTVAFLRNLPSFCLLPHEDQRRLLEGCWGPLFLLGLAQDTVTFEVAEAPVPSILKKILLEEPNSGAQGAQPPDPPQPSLAAVQWLQHCLESFWSLELGPKEYAYLKGTILFN--PDVPGLHASCHIAHLQQE-AHWALCEVLEPWYPASQGRLARILLMASTLKNISCTLLVDLFFRPVIGDVDITELLEDMLLLR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15466-1", "uniprot_id": "NR0B2_HUMAN", "id": "Q15466-1", "name": "Nuclear receptor subfamily 0 group B member 2", "aln": "MSTSQPGACPCQGAASRPAILYALLSSSLKA---VPRPRSRCLCRQHRPVQLCAPHRTCREALDVLAKTVAFLRNLPSFWQLPPQDQRRLLQGCWGPLFLLGLAQDAVTFEVAEAPVPSILKKILLEEPSSSGGSGQLPDRPQPSLAAVQWLQCCLESFWSLELSPKEYACLKGTILFN--PDVPGLQAASHIGHLQQE-AHWVLCEVLEPWCPAAQGRLTRVLLTASTLKSIPTSLLGDLFFRPIIGDVDIAGLLGDMLLLR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8L2-1", "uniprot_id": "A0AB13A8L2_DANRE", "id": "A0AB13A8L2-1", "name": "", "aln": "---MRKHLHPHG-------ILFNILTRKPEFAYFTSPE--PCHCNFECFVSLKNPEITCPAAFQVLTKSIHFMQSSLSHQNLSSSERLCLLQKRWVPLFILGLAQENISFEVMDFPVGSILRNILLS-------GQQKPDDCPLTLAKVNKLKMFLDKVWSLQLSLKEYACLKGAILFSQVLDSPGLKSSLVIAGLQEEFAHDLHMLILSRQRSEEHWTIMDVLFTACTLQMEARSMVTELFFRPIMGKMDIQELLNEIINNNVGL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * **: :*: . .. * *. . * * *. ** *::** *:: *::. *. *. .:: **: * ***:*****: ::*** : ** ***::***. . * .* :** *: *: *:..***:*. **** ***:***. * ***::: *. **:* ** :*. . : : :*: *.**: . ::: :*****::*.:** ** ::: . ", "identical_positions": 86, "similar_positions": 70, "identity": "32.33%" }, { "cls_id": "homologset.agr.RGD:621033", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63652-1", "uniprot_id": "OPSB_RAT", "id": "Q63652-1", "name": "Short-wave-sensitive opsin 1", "aln": "MSGEDEFYLFQNISSVGPWDGPQYHIAPVWAFHLQAAFMGFVFFAGTPLNATVLVATLHYKKLRQPLNYILVNVSLGGFLFCIFSVFTVFIASCHGYFLFGRHVCALEAFLGSVAGLVTGWSLAFLAFERYLVICKPFGNIRFNSKHALTVVLITWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSEHYTWFLFIFCFIIPLSLICFSYFQLLRTLRAVAAQQQESATTQKAEREVSHMVVVMVGSFCLCYVPYAALAMYMVNNRNHGLYLRLVTIPAFFSKSSCVYNPIIYCFMNKQFRACILEMVCRKPMTDESDMSGSQKTEVSTVSSSKVGPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51491-1", "uniprot_id": "OPSB_MOUSE", "id": "P51491-1", "name": "Short-wave-sensitive opsin 1", "aln": "MSGEDDFYLFQNISSVGPWDGPQYHLAPVWAFRLQAAFMGFVFFVGTPLNAIVLVATLHYKKLRQPLNYILVNVSLGGFLFCIFSVFTVFIASCHGYFLFGRHVCALEAFLGSVAGLVTGWSLAFLAFERYVVICKPFGSIRFNSKHALMVVLATWIIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSEYYTWFLFIFCFIIPLSLICFSYSQLLRTLRAVAAQQQESATTQKAEREVSHMVVVMVGSFCLCYVPYAALAMYMVNNRNHGLDLRLVTIPAFFSKSSCVYNPIIYCFMNKQFRACILEMVCRKPMADESDVSGSQKTEVSTVSSSKVGPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03999-1", "uniprot_id": "OPSB_HUMAN", "id": "P03999-1", "name": "Short-wave-sensitive opsin 1", "aln": "MS-EEEFYLFKNISSVGPWDGPQYHIAPVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCNGYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHALTVVLATWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVCGKAMTDESDTCSSQKTEVSTVSSTQVGPN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W6A9-1", "uniprot_id": "OP1S1_DANRE", "id": "Q9W6A9-1", "name": "Opsin-1, short-wave-sensitive 1", "aln": "--MDAWAVQFGNASKVSPFEGEQYHIAPKWAFYLQAAFMGFVFIVGTPMNGIVLFVTMKYKKLRQPLNYILVNISLAGFIFDTFSVSQVFVCAARGYYFLGYTLCAMEAAMGSIAGLVTGWSLAVLAFERYVVICKPFGSFKFGQGQAVGAVVFTWIIGTACATPPFFGWSRYIPEGLGTACGPDWYTKSEEYNSESYTYFLLITCFMMPMTIIIFSYSQLLGALRAVAAQQAESESTQKAEREVSRMVVVMVGSFVLCYAPYAVTAMYFANSDEPNKDYRLVAIPAFFSKSSCVYNPLIYAFMNKQFNACIMETVFGKKIDESSEVSS--KTETSSVSA------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * *.*.*::* ***:** *** ******* **: * *:*. **..*::**************:*:.**:: *** **:.:..**:.:* :**:*. :*::**********.******:*******.::*.. :*: .*: ** ** . : ********:***** :******* . :*.** **:**:* **::*:::* *** *** :*:****** ** :*********:********* :**.***. ***:.*. : . ***:**:*****:*:***:**.******.***:: * * : :.*: .. ***.*:**: ", "identical_positions": 196, "similar_positions": 87, "identity": "56.65%" }, { "cls_id": "homologset.agr.RGD:621034", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLS8-1", "uniprot_id": "OBRG_RAT", "id": "Q9JLS8-1", "name": "Leptin receptor gene-related protein", "aln": "-----MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFYVISPIPYFIAKR-----VTYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVAVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDDFSWEQW-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15243-1", "uniprot_id": "OBRG_HUMAN", "id": "O15243-1", "name": "Leptin receptor gene-related protein", "aln": "-----MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFHAISPIPHFIAKR-----VTYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVAVIKWGACGLVLAGNAVIFLTIQGFFLIFGRGDDFSWEQW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O89013-1", "uniprot_id": "OBRG_MOUSE", "id": "O89013-1", "name": "Leptin receptor gene-related protein", "aln": "-----MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFYVISPIPYFIAKR-----VTYDSDATSSACRELAYFFTTGIVVSAFGLPVVLARVDVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDDFSWEQW-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q561T9-1", "uniprot_id": "OBRG_DANRE", "id": "Q561T9-1", "name": "Leptin receptor gene-related protein", "aln": "-----MAGIKALVALSFSGALGLTFLLLGCALEQFGQYWPMFVLIFYILSPIPNLIARR-----HADDTES-SNACRELAYFLTTGIVVSAYGLPVVLARKAVIQWGAAGLVMAGNCVIFLTILGFFLIFGGGDDFSWEQW-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MMD0-1", "uniprot_id": "Q8MMD0_DROME", "id": "Q8MMD0-1", "name": "Leptin receptor gene-related protein", "aln": "-----MATLKALFICAFLTCIGVTFLILACAVPTTKIFYPFFVLLFYVLSVLPVFIARR-----TTPGNET--NPKSEFAHFLTAGMVLSAFALPIVLAHALVITWTASILTIISNIINYGTI--FWYAMRDDEPYGSMF--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47111-1", "uniprot_id": "VPS55_YEAST", "id": "P47111-1", "name": "Vacuolar protein sorting-associated protein 55", "aln": "MMEFKVSPLTKIISLSGFLALGFLLVILSCALFHN--YYPLFDILIFLLAPIPNTIFNAGNKYHTSDFMSDSSNTGQDLAHFLTGMLVTSGIALPVVFYHCQLIGHLSCIMCMIGGLIIYSSIVIFKWFFKKDFNEDDSLFG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :. :. : .:*. :::*.**: ::*:* :::. :: :* * . : . .. ::*:*:* :* *. .:*::: : :* :. : : .. : : :* * : . . ", "identical_positions": 17, "similar_positions": 55, "identity": "11.97%" }, { "cls_id": "homologset.agr.RGD:621035", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70628-1", "uniprot_id": "PDE9A_MOUSE", "id": "O70628-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "------------------------------------------------------------------------------------------------------------------------------------MGAGSSSYRPKAIYLDIDG--------------------------------------------------------------RIQKVVFSK---------------------YCNSSDIMDLFCIATGLPRNTT----------------------------------------------------------ISLLTTDDAMVSIDPTMPANSERTPYKVRPVAVKQVS--------------------------------------------------------------EREELIQGVLAQVAEQFS-------------------------------RAFKINELKAEVANHLAVLEKR-------------------------------------------VELEG--------------------------LKVVEIEKCKSDIKKMREELAARNSR------TNCPCKYSFLDN--------------------------------------KKLTPRRDVPTYPKY-------------LLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRNN-PFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKATAQIGFIKFVLIPMFET--VTKLFPVVEETMLRPLW-ESREHYEELKQLDDAMKELQKK-TESLTSGAPENTTEKNRDAKDSEGHSPPN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8QZV1-1", "uniprot_id": "PDE9A_RAT", "id": "Q8QZV1-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "------------------------------------------------------------------------------------------------------------------------------------MGAGSSSYRPKAIYLDIDG--------------------------------------------------------------RIQKVVFSK---------------------YCNSSDIMDLFCIATGLPRNTT----------------------------------------------------------ISLLTTDDAMVSIDPTMPANSERTPYKVRPVAVKQVS--------------------------------------------------------------EREELVQGVLAQVAEQFS-------------------------------RAFKINELKAEVANHLAMLEKR-------------------------------------------VELEG--------------------------LKVVEIEKCKSDIKKMREELAARNNR------TNCPCKYSFLDN--------------------------------------KKLTPRRDVPTYPKY-------------LLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRSN-PFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKATAQIGFIKFVLIPMFET--VTKLFPIVEETMLRPLW-ESREHYEELKQLDDAMKELQKK-TENLTSGATENAPEKTRDAKDNEDRSPPN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76083-1", "uniprot_id": "PDE9A_HUMAN", "id": "O76083-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "------------------------------------------------------------------------------------------------------------------------------------MGSGSSSYRPKAIYLDIDG--------------------------------------------------------------RIQKVIFSK---------------------YCNSSDIMDLFCIATGLPRNTT----------------------------------------------------------ISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTT--SRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFS-------------------------------RAFKINELKAEVANHLAVLEKR-------------------------------------------VELEG--------------------------LKVVEIEKCKSDIKKMREELAARSSR------TNCPCKYSFLDNH-------------------------------------KKLTPRRDVPTYPKY-------------LLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKATAQIGFIKFVLIPMFET--VTKLFPMVEEIMLQPLW-ESRDRYEELKRIDDAMKELQKK-TDSLTSGATEKSRERSRDVKNSEGDCA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B2M3-1", "uniprot_id": "A0A8M3B2M3_DANRE", "id": "A0A8M3B2M3-1", "name": "Phosphodiesterase", "aln": "------------------------------------------------------------------------------------------------------------------------------------MGSASSAY--RMIYLEVDG--------------------------------------------------------------RVQKVVFSR---------------------FCSPCDIKELFCTATGVSRNTS----------------------------------------------------------ISLLDSTGAMVSIDPTMPNNTERSPYKVVPVTGSQLA--------------------------------------------------------------DKEELFQNVLTQVAEQFS-------------------------------RAFKINELKTEVTNRLAMLEKR-------------------------------------------VELEG--------------------------MKVVEIEKCRSDIKKLREEMASRNNS-------------SFLEDN-------------------------------------KKLTPRRDVPSYPKY-------------HLSQDTVEALKQPLFDVWQWESNEMLSCLEHMYHDLGLVKDFNINPITLKRWLLCIHDNYRNN-PFHNFRHCFCVTQMMYSMIYLCGLQEKFTQVDILILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQIFSQPDCNIFASFDPEAFKQIRQGTITLILATDMARHGEIMDSFKQKVDSFDYNNEEHVTCLKMVLIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKAEGLPVAPFMDREK-VTKPTAQIGFIKFVLIPMFET--VMKLFPQIEEVMVQPLR-ESRDKYEELKQIDDAMNEMQKKKTENLTTGGKKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7UT66-1", "uniprot_id": "A0A8N7UT66_DANRE", "id": "A0A8N7UT66-1", "name": "Phosphodiesterase", "aln": "---------------------------------------------------------------------------------------------MSSCIYFRRHLAGGTFEGWFWWICSWLRVQVDLTVHFINMGSASSSYSPKTIYLDVDG--------------------------------------------------------------KVQKVLFSR---------------------HCSPCDIKELLCSSSNIPRNTA----------------------------------------------------------IMMTDPEGAIVSIDPTMPTNNPNFLYKIIPLSASQLG--------------------------------------------------------------EKEDMFQNVLSQVAEQFS-------------------------------RAFRINELKTEVTNRLAMLEKR-------------------------------------------VELEG--------------------------LKVVEIEKCKNDMRKLRDEMTSRAGAR-----VNCPCKYNFSDDG-------------------------------------KKLTPRRDIPSYPKY-------------TLSQETIEALKKPTFDVWHWEHNEMLSCLEYMYHDLGLVKEFNINPITLKRWLLGIQENYRSN-PFHNFRHCFCVSQMMYGMIHLCNLQEKLTLTDLGILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSLPECNIFANVEPEAFKQIRQAIITLILATDMARHGEILDSFKHKVDHFDFTNEEHVACLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEY---FMQSDREKSEGLPVAAFMDREK-VTKPTAQIGFIKFVLIPMFET--VMKLFPQIEEIMVQPLR-DSRDHYEELKQIDDAMTEAQKKKTESLSLGGKKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7S6-1", "uniprot_id": "PDE9A_DROME", "id": "Q9I7S6-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "MYQDSGCSSSSSRRGSSSAAAATSTAATAAETAAAAAATTTSSSDEETLETLTIITTTITDSDIHATTTTTTVIASGTATTAAAAATTATLATLATLASNSDIEDSSPVESEDSEECEYIEIDCQTTAQEGTSPSGGSSSSGNAVLLQRSSNNLQQQQQQQQQQQQHLQLQLQQADERLLRKIGYIASRVRCLSKYYGDFRLVNPYSARRQRRQLQEILLRHSIFDPGKEHQRAIVLAAATAAIAGPLAAIDCVCGSSSISLEAVSSRSRSSELEDDHHEQDQVQEEQEQEQHQGDTEDNEEEQEHPSEKPERTDIEEEPPPAIAVTTTTTATVRRKSSSSSTISGTATVSGSVSVSASASQSFCSNNINLLEELLIQFYEEQDHRSNLTVIRHHHHQQHQQHQQQQRITNNNNNNNNCNSIQNNNNMSNPAATAAATATPSVEQPATSGTTNIHLQPTSLPDGSDNPRRRRASDCSAVQAALQNQLHCITLK---NNNCGKAMPFHRGSCGAAGEHLLAANSIANRATIILSKSCSNVDGDATATAATALSSTVGGGIGGIGGSIKMRASATDIETNALNGARDAIVASNNGNNGNNGNNGNNEYSILQLNNTIIQCHFNDDDFRALVKDLKRKVEYTERMNWLCLSKRPLGPPHRKSSLPKHQEVKRRFLEICDTTFSEEVRAALRLPAFDSYEWSDADVIHLMQTMFVELGFIEKFSIPVDTLREWLYEVYKHYNEV-PFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQINARTELALRYNDISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEITPIFDYSNRAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEF---FAQSAAEKSEGLPVTPFMDPDK-VSKPGSQVRFIGLVLLPLFEA--LGELVPELTELIIIPVR-IALEYYRRLNDAQTKTRKSVADSNTSATSDSNSGTIDSNAAMVSTPGGASDKLSLDKGQGNSQGSGGGGGGGGGGGAGGGTGSGCGSNAAGSVSPQMPRSGSGISVKSRRSIPSQKSASRTSVDEPGGMASELHDLPEGSESGDSETATEVDVAEKTSKFKVDTEGSSNRSKSSHSTSRKSSREKRPSMIGELCSSGGGQRIRNSYGNIHGYHSNRCHFGNNRAVSLDQYSSAGNNRRLSDGLPQVISDSNVFYGRHNRSSTETTVAVGNPQDTNANTNHPVGCQLKELLARTEADSDGEGDGNGREDKKIPLVIPSMPQLATSSNGNISPTLVVTEQILPSNGSTRSSASSGRGGSGVPGGSGGSGMPGPSAGSGSSWKSRLRQFSDYFSFSFDKSNKRFGSTRSSPCPGSNSSSGRTNNNANGLGENQDGLGAGGGIKPGMCCTTITNSSGSTVKGETRGGTAGAGGGALTTMTTGNDAHQRHRAYSLDVPGMMRYSSNDSSRHPSNNTLQSAGGGAGLTTGLEVTAQRVPPSLSVEMGLASGSSSEAGPKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "-------------------------------------------------------------------------------------------------------------------MSTLFLIGIHEIEKSQTIVQNEHYFDRVIELQDLDS---------------------------------------------------------------LMVALYKDR---------------------VSPFPNVHNFETGVSIVLYDPS---------------------------------------------------------KFQLSVRQLDVLFKRFFPSFNISAIDHTREENLQRLECVE-----------------------------------------------------------RENSICRNRITRINHWMY-------------------------------------HHHDDTPDGINKNSYGTVN--------------------------------------G---------------------------------NSVPTQACEANIYTLLLHLNDSKAQH-----LRKASVPRLIRN--------------------------------------IEFMSFLSDPIEKIS-------------QEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATW---RLCTYLLKDNPVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLS-ISKKKFDFISE----AILATDMALHSQYEDRLMHENPMKQIT-------LISLIIKAADISNVTRTLSISARWAYLITLEFNDCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLSDNVKINKEYWMKHKKPQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : : .. . . . .: * . . . .:. . : : : : . : : : : : . . . . * * . ::: : .*. .. * .* * : . *.. ******.: * * : . : : :* :.: **:.*** ** *..:*:* .::::* ***.* : ::: ::: . . * * : ******* * : : . : . * ::** .**** .*. .:: * : *: . .*:. * * * * .. :: * :*: : :. : : * : : : : : :. *. . . . ", "identical_positions": 61, "similar_positions": 120, "identity": "3.97%" }, { "cls_id": "homologset.agr.RGD:621036", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40142-1", "uniprot_id": "TKT_MOUSE", "id": "P40142-1", "name": "Transketolase", "aln": "MEGYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKALDPRNPHNDRFVLSKGHAAPILYAVWAEAG-FLPEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYR---------VYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRLGQSDPAPLQHQVDIYQKRCEAFGWHTIIVDG--HSVEELCKAFG---QAKHQPTAIIAKTFKGRGITGIEDKEAWHGKPLPKNMAEQIIQEIYSQVQS------------KKKILATPPQ---EDAPSVDIANIRMPT--------------------PPSYKVG-DKIATRKAYGLALAKLGHASDRIIALDGDTKNSTFSELFKKEHPD-----------RFIECYIAEQNMVSIAVGCATR-DRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKG-ICFIRTSRPENAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAESL-KKDKISIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSAAVVGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDKDAIVQAVKGLVTKG-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50137-1", "uniprot_id": "TKT_RAT", "id": "P50137-1", "name": "Transketolase", "aln": "MEGYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKALDPRNPHNDRFVLSKGHAAPILYAVWAEAG-FLPEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYR---------VYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRLGQSDPAPLQHQVDVYQKRCEAFGWHAIIVDG--HSVEELCKAFG---QAKHQPTAIIAKTFKGRGITGIEDKEAWHGKPLPKNMAEQIIQEIYSQVQS------------KKKILATPPQ---EDAPSVDIANIRMPT--------------------PPNYKVG-DKIATRKAYGLALAKLGHASDRIIALDGDTKNSTFSELFKKEHPD-----------RFIECYIAEQNMVSIAVGCATR-DRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKG-ICFIRTSRPENAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAEML-KKEKIGVRVLDPFTIKPLDKKLILDCARATKGRILTVEDHYYEGGIGEAVSAVVVGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDKDAIVQAVKGLVTKG-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29401-1", "uniprot_id": "TKT_HUMAN", "id": "P29401-1", "name": "Transketolase", "aln": "MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAG-FLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYR---------VYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDG--HSVEELCKAFG---QAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQS------------KKKILATPPQ---EDAPSVDIANIRMPS--------------------LPSYKVG-DKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPD-----------RFIECYIAEQNMVSIAVGCATR-NRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKG-ICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELL-KKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVP4-1", "uniprot_id": "Q9VVP4_DROME", "id": "Q9VVP4-1", "name": "transketolase", "aln": "-MSNAKLDSKVVQNLKDVAQKLRIHSITSTQAAKSGHPTSCASLAEIMTVLFFQQMRLNLKHPRDPSSDRLVLSKGHAAPILYAVWAEAG-LFPVEELRNLRKVDSDLEGHPTPRLSFVDVSTGSLGQGISVAAGMAYVGKHLDKADYR---------TYVIVGDGEATEGAVWESLHFAGHYCLDNLCVIFDMNKIFCS---DIGTEMEVYRERLDAFGFNALVLNG--HDIDELAKAFINAASTKGKPTALLARTTKGKDFLGIEGIEEMHAQPLGK-RAESAIKHLQMKIAN------------PNVRLTPKKVGKCGHAPEVHINNIMLCS--------------------PPNYRLG-DSVAPRLAYGTALAKIAADNPRVIALDGDTKNSTYADKMRNAFPE-----------RFIECFTAQQNLVGVAVGATCR-RRTVAFVSTYATFFTRAFDQIRMGAISHTNVNFAGSHCGCSIGEDGPSQMGLEDMAMFRSIPGSTVFYPTDAVSTERAVELAANTKG-VCYIRTTYPSTTVIYNNDEVFAVGLGKVVRQKPSDEVLLIGAGVTLYECLAAAERL-EEDCITARVIDPFTVKPLDVGLIVKHGKLCRGRIVVVEDHYQQGGLGEAVLSALADYRNFVVKHLYITTVPRSGPPAVLLDMFGVSSRNIYKASLAIMKK--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHN7-1", "uniprot_id": "Q9VHN7_DROME", "id": "Q9VHN7-1", "name": "transketolase", "aln": "-MSYHKPEAKTVQDLKDLAQKLRIHSINATQASKSGHPTSCASIAEIMSVLFFQQLRLNLKHPRDPSSDRFILSKGHAAPILYAAWAEAG-LFPIADLNNLRKIDSDLEGHPTPRLNFIDVGTGSLGQGVAVGAGMAYVGKNFDKADYR---------TYVVVGDGESAEGSIWESLHFAGHYKLDNLCVIFDVNRLGQSEATSLQHKLDVYRDRLEAFGFNAVVVDG--HDVEELSKAFHCAAITKNKPTAIIAKTFKGRDFPNIEDLDNWHGKPLGD-KAAEVVKHLEGLIVN------------KNVKLTPKPVPKTGAAPDVDINNIKLSS--------------------PPAYKLG-DSIATRLAYGTALAKIGQNNLRVVALDGDTKNSTFSDKLKNLDPQ-----------RYIECFIAEQNLVGVAVGAACR-RRTVAFVSTFATFFTRAFDQIRMGAISQTNVNFVGSHCGCSIGEDGPSQMGLEDIAMFRTIPGSTIFYPSDAVSTERAVELAANTKG-VCFIRTSRPNTCVIYDNEEPFTIGRGKVVRQKSSDEVLLIGAGITLYECLAAADQL-EKNCITVRVIDPFTVKPLDAELIIEHGKQCGGRVVVVEDHYQQGGLGEAVLSALAGERNFVVKHLYVPTVPRSGPPSVLIDMFGISARHVVNAVNEILKD--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33315-1", "uniprot_id": "TKT2_YEAST", "id": "P33315-1", "name": "Transketolase 2", "aln": "-------MAQFSDIDKLAVSTLRLLSVDQVESAQSGHPGAPLGLAPVAHVIFK-QLRCNPNNEHWINRDRFVLSNGHSCALLYSMLHLLGYDYSIEDLRQFRQVNSRTPGHPEFHSAGVEITSGPLGQGISNAVGMAIAQANFAATYNEDGFPISDSYTFAIVGDGCLQEGVSSETSSLAGHLQLGNLITFYDSNSISIDGKTSYSFDEDVLKR-YEAYGWEVMEVDKGDDDMESISSALEKAKLSKDKPTIIKVTTTIGFGSLQQG-TAGVHGSALKADDVKQLKKRWGFDPNKSFVVPQEVYDYYKKTVVEPGQKLNEEWDRMFEEYKTKFPEKGKELQRRLNGELPEGWEKHLPKFTPDDDALATRKTSQQVLTNMVQVLPELIGGSADLTPSNLTRWEGAVDFQPPITQLGNYAGRYIRYGVREHGMGAIMNGISAFGANYKPYGGTFLNFVSYAAGAVRLAALSGNPVIWVATHDSIGLGEDGPTHQPIETLAHLRAIPNMHVWRPADGNETSAAYYSAIKSGRTPSVVALSRQNLPQLEHSSFEKALKGGYVIHDVENPDIILVSTGSEVSISIDAAKKLYDTKKIKARVVSLPDFYTFDR-------QSEEYRFSVLPDGVP---IMSFEVLATSSWGKYAHQSFGLDEFGRSGKGPEIYKLFDFTADGVASRAEKTINYYKGKQLLSPMGRAF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P23254-1", "uniprot_id": "TKT1_YEAST", "id": "P23254-1", "name": "Transketolase 1", "aln": "-------MTQFTDIDKLAVSTIRILAVDTVSKANSGHPGAPLGMAPAAHVLWS-QMRMNPTNPDWINRDRFVLSNGHAVALLYSMLHLTGYDLSIEDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQGISNAVGMAMAQANLAATYNKPGFTLSDNYTYVFLGDGCLQEGISSEASSLAGHLKLGNLIAIYDDNKITIDGATSISFDEDVAKR-YEAYGWEVLYVENGNEDLAGIAKAIAQAKLSKDKPTLIKMTTTIGYGSLHAG-SHSVHGAPLKADDVKQLKSKFGFNPDKSFVVPQEVYDHYQKTILKPGVEANNKWNKLFSEYQKKFPELGAELARRLSGQLPANWESKLPTYTAKDSAVATRKLSETVLEDVYNQLPELIGGSADLTPSNLTRWKEALDFQPPSSGSGNYSGRYIRYGIREHAMGAIMNGISAFGANYKPYGGTFLNFVSYAAGAVRLSALSGHPVIWVATHDSIGVGEDGPTHQPIETLAHFRSLPNIQVWRPADGNEVSAAYKNSLESKHTPSIIALSRQNLPQLEGSSIESASKGGYVLQDVANPDIILVATGSEVSLSVEAAKTL-AAKNIKARVVSLPDFFTFDK-------QPLEYRLSVLPDNVP---IMSVEVLATTCWGKYAHQSFGIDRFGASGKAPEVFKFFGFTPEGVAERAQKTIAFYKGDKLISPLKKAF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * .. :*: :: . : **** : . * *:: :* : . **::**:**: .:**: * . :* ::*::.* *** . :: :*.****:. . *** . : : . .: .:*** ** *: :*. *.** .: * * : . . :: : :*:*:..: :: ..: :..*: :* :** : * * . *. .* . . .. . : : . . : : * : . :*.* .* .: .::. ..* . *. : : *:*. :: : .: * : . .: .*: *.: * . :*:.*:* : .:* . .:*****:: :* :* :*::* :: *:*. .. * : :: . : : . : .. . *: . . :: ::.:* : .: **. * . * **:. . .:* : *. .: * : . . . : : . ** . : .:*.. : . : ", "identical_positions": 96, "similar_positions": 197, "identity": "13.69%" }, { "cls_id": "homologset.agr.RGD:621037", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60866-1", "uniprot_id": "RS20_HUMAN", "id": "P60866-1", "name": "Small ribosomal subunit protein uS10", "aln": "--MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60868-1", "uniprot_id": "RS20_RAT", "id": "P60868-1", "name": "Small ribosomal subunit protein uS10", "aln": "--MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60867-1", "uniprot_id": "RS20_MOUSE", "id": "P60867-1", "name": "Small ribosomal subunit protein uS10", "aln": "--MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55828-1", "uniprot_id": "RS20_DROME", "id": "P55828-1", "name": "Small ribosomal subunit protein uS10", "aln": "MAAAPKDIEKPHVGDSASVHRIRITLTSRNVRSLENVCRDLINGAKNQNLRVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRIIDLHSPSEIVKKITSINIEPGVEVEVTIAN-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38701-1", "uniprot_id": "RS20_YEAST", "id": "P38701-1", "name": "Small ribosomal subunit protein uS10", "aln": "MSDFQKEKVEEQEQQQQQIIKIRITLTSTKVKQLENVSSNIVKNAEQHNLVKKGPVRLPTKVLKISTRKTPNGEGSKTWETYEMRIHKRYIDLEAPVQIVKRITQITIEPGVDVEVVVASN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : . : :******* :*:.**:*. :::..*:::** *****:***.*:*:***** *******: ::****** ***.:* :***:**.*.*****:***.:*. ", "identical_positions": 62, "similar_positions": 35, "identity": "51.24%" }, { "cls_id": "homologset.agr.RGD:621038", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05765-1", "uniprot_id": "RS21_RAT", "id": "P05765-1", "name": "Small ribosomal subunit protein eS21", "aln": "MQNDAGEFVDLYVPRKCSASNRIIAAKDHASIQMNVAEVDRSTGRFNGQFKTYGICGAIRRMGESDDSILRLAKADGIVSKNF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQR2-1", "uniprot_id": "RS21_MOUSE", "id": "Q9CQR2-1", "name": "Small ribosomal subunit protein eS21", "aln": "MQNDAGEFVDLYVPRKCSASNRIIAAKDHASIQMNVAEVDRTTGRFNGQFKTYGICGAIRRMGESDDSILRLAKADGIVSKNF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63220-1", "uniprot_id": "RS21_HUMAN", "id": "P63220-1", "name": "Small ribosomal subunit protein eS21", "aln": "MQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQMNVAEVDKVTGRFNGQFKTYAICGAIRRMGESDDSILRLAKADGIVSKNF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUG5-1", "uniprot_id": "RS21_DANRE", "id": "Q7ZUG5-1", "name": "Small ribosomal subunit protein eS21", "aln": "MQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQINIAEVDRVTGRFNGQFKTYAICGAIRRMGEADDSLLRLAKTDSIVAK------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76927-1", "uniprot_id": "RS21_DROME", "id": "O76927-1", "name": "Small ribosomal subunit protein eS21", "aln": "MENDAGENVDLYVPRKCSASNRIIHAKDHASVQLSIVDVDPETGRQTDGSKTYAICGEIRRMGESDDCIVRLAKKDGIITKNF----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C0V8-1", "uniprot_id": "RS21A_YEAST", "id": "P0C0V8-1", "name": "Small ribosomal subunit protein eS21A", "aln": "MENDKGQLVELYVPRKCSATNRIIKADDHASVQINVAKVDEEGRAIPGEYVTYALSGYVRSRGESDDSLNRLAQNDGLLKNVWSYSR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q3E754-1", "uniprot_id": "RS21B_YEAST", "id": "Q3E754-1", "name": "Small ribosomal subunit protein eS21B", "aln": "MENDKGQLVELYVPRKCSATNRIIKADDHASVQINVAKVDEEGRAIPGEYITYALSGYVRSRGESDDSLNRLAQNDGLLKNVWSYSR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:** *: *:*********:**** *.****:*:.:..** . **.:.* :* **:**.: ***: *.:: : ", "identical_positions": 38, "similar_positions": 24, "identity": "43.68%" }, { "cls_id": "homologset.agr.RGD:621039", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62267-1", "uniprot_id": "RS23_MOUSE", "id": "P62267-1", "name": "Small ribosomal subunit protein uS12", "aln": "MGK--CRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62268-1", "uniprot_id": "RS23_RAT", "id": "P62268-1", "name": "Small ribosomal subunit protein uS12", "aln": "MGK--CRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62266-1", "uniprot_id": "RS23_HUMAN", "id": "P62266-1", "name": "Small ribosomal subunit protein uS12", "aln": "MGK--CRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8T3U2-1", "uniprot_id": "RS23_DROME", "id": "Q8T3U2-1", "name": "Small ribosomal subunit protein uS12", "aln": "MGK--PRGLRTARKHVNHRRDQRWADKDYKKAHLGTRWKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPRDGSLNYIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX29-1", "uniprot_id": "RS23A_YEAST", "id": "P0CX29-1", "name": "Small ribosomal subunit protein uS12A", "aln": "MGKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX30-1", "uniprot_id": "RS23B_YEAST", "id": "P0CX30-1", "name": "Small ribosomal subunit protein uS12B", "aln": "MGKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ***.:*** ***:::* :::*** *** *:.****:**********:*:*:*********************:*****.**.**:::******:*******:* *************:.******:* ***:***", "identical_positions": 106, "similar_positions": 26, "identity": "73.1%" }, { "cls_id": "homologset.agr.RGD:621040", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62847-1", "uniprot_id": "RS24_HUMAN", "id": "P62847-1", "name": "Small ribosomal subunit protein eS24", "aln": "MN-DTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEK-KKTSRKQRKERKNRMKKVRGTAK--ANVGAGKKPKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62849-1", "uniprot_id": "RS24_MOUSE", "id": "P62849-1", "name": "Small ribosomal subunit protein eS24", "aln": "MN-DTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEK-KKTSRKQRKERKNRMKKVRGTAK--ANVGAGKKPKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62850-1", "uniprot_id": "RS24_RAT", "id": "P62850-1", "name": "Small ribosomal subunit protein eS24", "aln": "MN-DTVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPDVIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEK-KKTSRKQRKERKNRMKKVRGTAK--ANVGAGKKPKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W229-1", "uniprot_id": "Q9W229_DROME", "id": "Q9W229-1", "name": "40S ribosomal protein S24", "aln": "MSGTTATIRTRKFMTNRLLARKQMVCDVLHPGLSSVNKTEIREKLAAMYKVTPDVVFAFGFRTNFGGGRSTGFALIYDTLDFAKKFEPKYRLARHGLFEQ-KKQTRKQRKERRNRMKKVRGTAK--AKIGTGKK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX31-1", "uniprot_id": "RS24A_YEAST", "id": "P0CX31-1", "name": "Small ribosomal subunit protein eS24A", "aln": "MS-DAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX32-1", "uniprot_id": "RS24B_YEAST", "id": "P0CX32-1", "name": "Small ribosomal subunit protein eS24B", "aln": "MS-DAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :.******.::* ** ***:* *****. :.* * *:***** :**. *.: .*****:****::.**.::*::: *** **.:**.*:** *: :* :*:***:::** **: **.* *: : :: ", "identical_positions": 66, "similar_positions": 43, "identity": "48.18%" }, { "cls_id": "homologset.agr.RGD:621042", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63789-1", "uniprot_id": "P55G_RAT", "id": "Q63789-1", "name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYNTVWSMDRDDADWREVMMPYSTELI----FYIEMDP----------------------PALPPKPPKPVTSAVTNGMKDCF-VSLQDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGNYGFSEPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKED-NIDAVGKNLQEFHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKDYIERFRREG---------------NEKEIERIMMNYDKLKSRLGEIHDSKVRLEQDLKKQALDNREIDKKMNSIKPDLIQLRKIRDQHLVWLNHRGVRQRRLNAWLGIKSEDTDESYFINEDDESLPHYDEKTWFVEDVNRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKPCVIYSPARGYGFAEPYNLYGSLKELVLHYQQTSLVQHNDSLNVTLAYPVHAQMPSLCR-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64143-1", "uniprot_id": "P55G_MOUSE", "id": "Q64143-1", "name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYNTVWSMDRDDADWREVMMPYSTELI----FYIEMDP----------------------PALPPKPPKPMTPAVTNGMKDSF-ISLQDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSEPLTFTSVVELINHYHHESLAQYNPKLDVKLTYPVSRFQQDQLVKED-NIDAVGKNLQEFHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKDYIERFRREG---------------NEKEIERIMMNYDKLKSRLGEIHDSKLRLEQDLKKQALDNREIDKKMNSIKPDLIQLRKIRDQHLVWLNHRGVRQRRLNAWLGIKNEDSDESYFINEEDENLPHYDEKTWFVEDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPTLCR-------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92569-1", "uniprot_id": "P55G_HUMAN", "id": "Q92569-1", "name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYNTVWSMDRDDADWREVMMPYSTELI----FYIEMDP----------------------PALPPKPPKPMTSAVPNGMKDSS-VSLQDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKED-NIDAVGKKLQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEYIERFRREG---------------NEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNREIDKKMNSIKPDLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFVEDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLR5-1", "uniprot_id": "A0A8M9PLR5_DANRE", "id": "A0A8M9PLR5-1", "name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "aln": "MSSDSFFQYRALFEYKQERGDDISLQPGDLLTVSKMALLASEYQEGDEKCPKGWLHGTNERTKEKGNFPGTFVEYVGVVRTGLTSGKPWPRPVPPTPVGPQPPGASASEGPCGKADVVEQCALPDPSPVVVLRLTEALERLDWENEPLYRSGQASTGPPELLQALETDPAAVDFEQYELSTLADALRSYIQDLPCPLIPAVVYSELVYTAQEIQSMEECGQQLKTILDSPSVPQANHQLLVHLTRHLSKVAQSGGAAQASPKILALAYSEAVFKNNHFSADVNPEHHVKILEALIMVGGLVEIQAAPALPPKPTKPMTPVNGNGVKEAASGSLQEAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELISHYRHESLAQYNTKLDVKLMYPVSRYQQDQLVKED-NIDAVGRKLQEYHNQYQEKSKEYDRLYEEHTKTSQEIQMKRTAIEAFNETIKIFEEQCHTQERYSKEYIERFRREG---------------NDKEIERIMMNYEKLKSRLGEIHDSKTRLEQDLKTQALDNRETDKKMNSLKPDLIQLRKIRDQYLVWLNHKGVRQKRINDWLGLKNETTDDAYFVSEEDENLPHYDEKSWFVGDLNRTQSEDLLHGKPDGAFLIRESSKKGCYACSVVVEGEVKHCVIYSTPRGFGFAEPYNLYSTLKDLVLHYHQTSLVQHNDSLNVRLAYPVYAQMPSGPRR------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IUJ2-1", "uniprot_id": "A0A0R4IUJ2_DANRE", "id": "A0A0R4IUJ2-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSAETFS----YIEMSR------------------------VSPAGTVNSTDDHLQTQREPS-DLLQDAEWYWADISREEVNEILHGMPDGAFLVRDASCKVQGEYTLTVRNNGTNKLIRILHQEGKFGFSEPLTFSSVPELISFYRHRSLVHYNTSLDVTLAYPVTHCNTDLPVKEE-FLSATREKLQECFRVFQ-KTAEYDQLYDTCTSLLKEIQ-RRKAFEDISMT-EISKPQCYSQE----NFQNTLQKES---------------GCEELLR---------------------------------------------------------------------------------------------------EESWFVGDLARGPAEELLLGKPNGAFLIRNSSSKDCYACSVVVNSQVRHCVIRHTERGYGFVEPFDLHKSLKDLVLHYSQTSLAQHNQALDVRLAYPVHMSSVPTV--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KTZ2-1", "uniprot_id": "Q7KTZ2_DROME", "id": "Q7KTZ2-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRPQAPGSLVDPNEDELRMAPWYWGRISREEAKSILHGKPDGSFLVRDALS-MKGEYTLTLMKDGCEKLIKICHMDRKYGFIETDLFNSVVEMINYYKENSLSMYNKTLDITLSNPIVRAREDEESQPHGDLCLLSNEFIRTCQLLQNLEQNLENKRNSFNAIREELQEKKLHQSVFGNTEKIFRNQIKLNESFMKAPADAPSTEAGGAGDGANAAASAAANANARRSLQEHKQTLLNLLDALQAKGQVLNHYMENKKKEELLLERQINALKPELQILQLRKDKYIERLKGFNLKDDDLKMILQMG---FDKWQQLYETVSNQPHSNEALWLLKDAKRRNAEEMLKGAPSGTFLIR-ARDAGHYALSIACKNIVQHCLIYETSTGFGFAAPYNIYATLKSLVEHYANNSLEEHNDTLTTTLRWPVLYWKNNPLQVQMIQLQEEMDLEYEQAATLRPPPMMGSSAPIPTSRSREHDVVDGTGSLEAEAAPASISPSNFSTSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: * ***. *****.:. *:. ***:****** ::*:****: :.* :***:* * : ::** :. *.** *:*..*:..** ** .**:.* *: : . * : . : .:: . * : :. : . :*:* :: . :. * :* . * :* : *. . : * *:: * * :*::* * *.*:**** : . . ** *:. .. *: *:* . *:**. *:::: :**.** ** :.** :**::* . * :** ", "identical_positions": 93, "similar_positions": 93, "identity": "11.38%" }, { "cls_id": "homologset.agr.RGD:621043", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62851-1", "uniprot_id": "RS25_HUMAN", "id": "P62851-1", "name": "Small ribosomal subunit protein eS25", "aln": "MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62852-1", "uniprot_id": "RS25_MOUSE", "id": "P62852-1", "name": "Small ribosomal subunit protein eS25", "aln": "MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62853-1", "uniprot_id": "RS25_RAT", "id": "P62853-1", "name": "Small ribosomal subunit protein eS25", "aln": "MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PBI5-1", "uniprot_id": "RS25_DANRE", "id": "Q6PBI5-1", "name": "Small ribosomal subunit protein eS25", "aln": "MPPKDSKQKKDAGKS-KKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLYKEVPNYKLITPAVVSERLKIRGSLARAALQELLGKGLIKLVSKHRAQVIYTRNTKGTDEAAPEKEA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P48588-1", "uniprot_id": "RS25_DROME", "id": "P48588-1", "name": "Small ribosomal subunit protein eS25", "aln": "MPPKKD-AKSSAKQPQKTQKKKEGSGGGKAKKKKWSKGKVRDKLNNQVLFDKATYEKLYKEVPAYKLITPSVVSERLKIRGSLAKRALIELREKGLIKQVVQHHSQVIYTRATKGDEA-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C0T4-1", "uniprot_id": "RS25B_YEAST", "id": "P0C0T4-1", "name": "Small ribosomal subunit protein eS25B", "aln": "MPPKQQ--------LSKAAKAAAALAGGKKSKKKWSKKSMKDRAQHAVILDQEKYDRILKEVPTYRYVSVSVLVDRLKIGGSLARIALRHLEKEGIIKPISKHSKQAIYTRAAASE---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q3E792-1", "uniprot_id": "RS25A_YEAST", "id": "Q3E792-1", "name": "Small ribosomal subunit protein eS25A", "aln": "MPPKQQ--------LSKAAKAAAALAGGKKSKKKWSKKSMKDRAQHAVILDQEKYDRILKEVPTYRYVSVSVLVDRLKIGGSLARIALRHLEKEGIIKPISKHSKQAIYTRATASE---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.. * * .*** .****** .::*: :: *::*: .*::: **** *: :: :*: :**** ****: ** .* :*:** : :* *.**** : . ", "identical_positions": 45, "similar_positions": 32, "identity": "36.0%" }, { "cls_id": "homologset.agr.RGD:621044", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62854-1", "uniprot_id": "RS26_HUMAN", "id": "P62854-1", "name": "Small ribosomal subunit protein eS26", "aln": "MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPR---FRPAGAAPRPPPKPM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62856-1", "uniprot_id": "RS26_RAT", "id": "P62856-1", "name": "Small ribosomal subunit protein eS26", "aln": "MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPR---FRPAGAAPRPPPKPM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62855-1", "uniprot_id": "RS26_MOUSE", "id": "P62855-1", "name": "Small ribosomal subunit protein eS26", "aln": "MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPR---FRPAGAAPRPPPKPM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P13008-1", "uniprot_id": "RS26_DROME", "id": "P13008-1", "name": "Small ribosomal subunit protein eS26", "aln": "MTKKRRNGGRNKHNRGHVKPVRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDITEASIWDSYVLPKLYAKLHYCVSCAIHSKVVRNRSREARRIRTPPLR---SFPKDMARNNQNRK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39938-1", "uniprot_id": "RS26A_YEAST", "id": "P39938-1", "name": "Small ribosomal subunit protein eS26A", "aln": "MPKKRASNGRNKKGRGHVKPVRCVNCSKSIPKDKAIKRMAIRNIVEAAAVRDLSEASVYPEYALPKTYNKLHYCVSCAIHARIVRVRSREDRKNRAPPQRPRFNRENKVSPADAAKKAL", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39939-1", "uniprot_id": "RS26B_YEAST", "id": "P39939-1", "name": "Small ribosomal subunit protein eS26B", "aln": "MPKKRASNGRNKKGRGHVKPVRCVNCSKSIPKDKAIKRMAIRNIVEAAAVRDLSEASVYPEYALPKTYNKLHYCVSCAIHARIVRVRSREDRKNRAPPQRPRFNRDNKVSPAAAAKKAL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*** ..** *:.****:*:**.**::.:*******::.************::***:: *.*** * ***********:::** **** *: *:** * : : ", "identical_positions": 65, "similar_positions": 27, "identity": "54.62%" }, { "cls_id": "homologset.agr.RGD:621045", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P42677-1", "uniprot_id": "RS27_HUMAN", "id": "P42677-1", "name": "Small ribosomal subunit protein eS27", "aln": "MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZWU9-1", "uniprot_id": "RS27_MOUSE", "id": "Q6ZWU9-1", "name": "Small ribosomal subunit protein eS27", "aln": "MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24051-1", "uniprot_id": "RS27L_RAT", "id": "P24051-1", "name": "Small ribosomal subunit protein eS27-like", "aln": "MPLARDLLHPSLEEEKKKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VBU9-1", "uniprot_id": "Q9VBU9_DROME", "id": "Q9VBU9-1", "name": "40S ribosomal protein S27", "aln": "MPLAKDLLHPLPAEEKRKHKLKRLVQHPNSYFMDVKCPGCYRITTVFSHAQGVVVCAGCATILCQPTGGRAKLTEGCSFRRKPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35997-1", "uniprot_id": "RS27A_YEAST", "id": "P35997-1", "name": "Small ribosomal subunit protein eS27A", "aln": "MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNITTVFSHAQTAVTCESCSTILCTPTGGKAKLSEGTSFRRK--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38711-1", "uniprot_id": "RS27B_YEAST", "id": "P38711-1", "name": "Small ribosomal subunit protein eS27B", "aln": "MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNITTVFSHAQTAVTCESCSTVLCTPTGGKAKLSEGTSFRRK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.:***** .* :*** * *** *.***:******* .********* .* * .*:*:** ****:*:*:** ***** ", "identical_positions": 54, "similar_positions": 14, "identity": "64.29%" }, { "cls_id": "homologset.agr.RGD:621046", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62857-1", "uniprot_id": "RS28_HUMAN", "id": "P62857-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62858-1", "uniprot_id": "RS28_MOUSE", "id": "P62858-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62859-1", "uniprot_id": "RS28_RAT", "id": "P62859-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PBK3-1", "uniprot_id": "RS28_DANRE", "id": "Q6PBK3-1", "name": "Small ribosomal subunit protein eS28", "aln": "MDASRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDSNRSIIRNVKGPVREGDVLTLLESEREARRLR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W334-1", "uniprot_id": "RS28_DROME", "id": "Q9W334-1", "name": "Small ribosomal subunit protein eS28", "aln": "MD----KPVVWARVMKVLGRTGSQGQCTQVKVEFLGEQNRQIIRNVKGPVREGDILTLLESEREARRLR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAB9-1", "uniprot_id": "Q9VAB9_DROME", "id": "Q9VAB9-1", "name": "Small ribosomal subunit protein eS28", "aln": "MD----KPQ-YARVVEILGRTGSQGQCTQVRVEFLGDQSRQIIRNVKGPVRVGDILSLLETEREARRLR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q3E7X9-1", "uniprot_id": "RS28A_YEAST", "id": "Q3E7X9-1", "name": "Small ribosomal subunit protein eS28A", "aln": "MDN--KTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNVKGPVRENDILVLMESEREARRLR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0C0X0-1", "uniprot_id": "RS28B_YEAST", "id": "P0C0X0-1", "name": "Small ribosomal subunit protein eS28B", "aln": "MDS--KTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNVKGPVRENDILVLMESEREARRLR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *:* ::******:* ***:***: : .* *:******** .*:* *:*:********", "identical_positions": 40, "similar_positions": 13, "identity": "57.97%" }, { "cls_id": "homologset.agr.RGD:621047", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUC8-1", "uniprot_id": "PLRG1_RAT", "id": "Q9WUC8-1", "name": "Pleiotropic regulator 1", "aln": "-MVEEVQKHSVHTL----VFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPTSK-ENLKEKGPQNAPDSYPHKQYPANQGQDVEYLVTGTHPYPPGPGVALTADTKIQRMPSESAAQSLAVALPSQTRVDANRTAPAGSEYRHPGASDRSQPTAMNSMIMETSNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEP-GNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPLHYTFASGSPDNIKQWKFPDGGFIQNLSG-HNAIINTLAVNTDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDRSESRLLTAEADKTIKVYREDETATEETHP-VSWKPEIIKRKRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922V4-1", "uniprot_id": "PLRG1_MOUSE", "id": "Q922V4-1", "name": "Pleiotropic regulator 1", "aln": "-MVEEVQKHSVHTL----VFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPTSK-ENLKEKGPQNATDSYPHKQYPANQGQDVEYLVTGTHPYPAGPGVALTADTKIQRMPSESAAQSLAVALPSQTRVDANRTGPAGSEYRHPGASDRSQPTAMNS-IMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEP-GNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPLLYTFASGSPDNIKQWKFPDGGFIQNLSG-HNAIINTLAVNADGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDRSESRLLTAEADKTIKVYREDETATEETHP-VSWKPEIIKRKRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43660-1", "uniprot_id": "PLRG1_HUMAN", "id": "O43660-1", "name": "Pleiotropic regulator 1", "aln": "-MVEEVQKHSVHTL----VFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPTSK-ENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSESAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEP-GNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSG-HNAIINTLTVNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVYREDDTATEETHP-VSWKPEIIKRKRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VYQ9-1", "uniprot_id": "Q9VYQ9_DROME", "id": "Q9VYQ9-1", "name": "Pleiotropic regulator 1", "aln": "MAMEDVQKHSVHTL----IFRSLKRTHDLFVSNQGNLPEIDERLEKLRRSIKAKDGYGLVLDKVAKIGEARKASGAQTPGD----KTLAITDG--------SATDAASGAGSLVKYNAGAR--PAEKTAP-----LVTGTHTSLVRASLANS------NADMSANGAIAS---------HLQLIPKKAPSIPKPKWHAPWKLSRVISGHLGWVRCIAVEP-GNEWFATGAGDRVIKIWDLASGKLKLSLTGHVSTVRGVAVSTKHPYLFSCGEDRQVKCWDLEYNKVIRHYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQIITGSHDSTVRLWDLAAGKSVCTLTNHKKSVRSIVLHPSLYMFASASPDNIKQWRCPEGKFVQNISG-HTSIVNCMAANSEGVLVSGGDNGTMFFWDWRTGYNFQRFQAPVQPGSMDSEAGIFAMCFDQSGSRLITAEADKTIKVYKEDDEASEESHP-INWRPDLLKRRKF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12417-1", "uniprot_id": "PRP46_YEAST", "id": "Q12417-1", "name": "Pre-mRNA-splicing factor PRP46", "aln": "---MDGNDHKVENLGDVDKFYSRIRWNNQFSYMATLPPHLQSEMEGQKSLLMRYDTY-------------RKESSS------------------------------FSGEGKKVTLQHVPTDFSEASQAV------ISKKDHDTHASAFVNKIF----QPEVAEELIVNR---------YEKLLSQ------RPEWHAPWKLSRVINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVVSSSTDATVRLWDVVAGKTMKVLTHHKRSVRATALHPKEFSVASACTDDIRSWGLAEGSLLTNFESEKTGIINTLSINQDDVLFAGGDNGVLSFYDYKSGHKYQSLATREMVGSLEGERSVLCSTFDKTGLRLITGEADKSIKIWKQDETATKESEPGLAWNPNLS-AKRF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.*.*..* * * * :: * ::.. . : : : * * ... .* * :. : . . * . . :. .. .: . : *:.: :*:**.**** ***.********:*::* .*:** **: * .:*:****:**** :*:**: ***.* ** : ***** .**: ******* *::**.*:****.* : :***:*::.*..***. ::**:**: * ** **...: * . ..:**:::.* *:*:****:.***: .**:**:***: .*** : .**...*:*:.* .:* :: *:.. :..*:* :: * :.**.:*.***.: ::*:::*:::* . : **::.* .::. **:: **:*.****:**::::*: *::*:.* : *.*:: ::*", "identical_positions": 160, "similar_positions": 164, "identity": "30.59%" }, { "cls_id": "homologset.agr.RGD:621048", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63505-1", "uniprot_id": "TF3C1_RAT", "id": "Q63505-1", "name": "General transcription factor 3C polypeptide 1", "aln": "------MDALESLLDEVALEGLDGLCLPALWSRLESRSPAFPLPLEPYTQEFLWRALVTHP--GISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVTLEDVYPIHMILENKDGIQGSCRYFKERKDITSSIRSKCLQPRCTMVEAFSRWGKKLIIVASQDMRYRALIGLEGDPDLKLPDFSYCILERLGRSRWQGELQR-DLHTTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHVDRRSKYDILMEKLSMMLSTRSNQIETLGKLREELGLCERTFKRLYQYMLNAGLAKVVSLPLQEIHPECGPCKTKKGTDVMVRCLKLLKEFRRKMEDDHDDDDDEEAISKAVPPVDIVFERDMLTQTYELIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYAREKARGELLTTVSLASVQDESLMPEGEEAFLSDSESEEESSCSG-KRRGRGSRGHSRASGDAGPGSRPHHSTPAKGGWKVLNLHPLKKPK----SAAVERSRRSSACRDG-LDTSSSSELNIPFDPHSMDSHSGDIAVIEEVRLDNPKEGGGSQKGGRHGSGQDKPHKTYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIIRLVRNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKVPPAPAPQEEAEEGNQEPEVPSRSADSEANTSSKPESTRVKKTDEKMGITPLKNYKPVIVPGLGRSIGFLPKMPRLRVMHLFLWYLVYGHPASHTGEQPTFHSERKTGKQEPSRPGVQPSS-GDDWDSS---EAKNSTESSSWEAEMELSTERVYVDEISWMRYVPPIPIHRDFGFGWALVSDILLCLPLSIFVQVVQVSYKVDN-LEDFLNDPLKKHTLIRFLPRHIRQQLLYKRRYIFSVVENLQRLCYMGLLQFGPTEKFQDKDQVFVFLKKNAVIVDTTICDPH-YNLAHSSRPFERRLYVLDSMQDVESYWFDLQCICLNTPLGVVRCPCAQKICP-DPGSDPEGSLRKEQESAMDKHNLERKCAMLEYTTGSREVVDEGLVPGDGLGAAGLDSSFYAHLKRNWVWTSYIINKARK-NNTSENGLTGRLQTFLSKRPMPLGSGGSGRLPLWSEGKADAELCADKEEHFELDREPTPGRNRKVRGGKSQKRKRLKKEPIRKTKRRRRGEHPEAKSKKLRYQDEADQNALRMMTRLRVSWSMQEDGLLMLCRIASNVLNT-KVKGPFVTWQVVRDILHATFEESLDKTSHSVGRRARYIVKNPQAF---------MNYKVCLAEVYQDKALVGDFMSRKDNYEDPKVCAKEFKEFVEKLKEKFS--SGLRNPNLEIPDTLQELFAKYRVLAIGDEKDRVRKEDELNSVEDIHFLVLQNLIQSTLSLSNSQSNSCQSFQIFRLYREFREPVLVRAFMECQKRSLVNRRRVSHSQGPKKNRAVPFVPMSYQLSQSYYKLFTWRFPTTVCTESFQFYDRLRANGILDQPD-HFSFKDMDSNDPSSDLVAFSLDSPGGHCVTALALFSLGLLSVDVRIPEQIVVVDSSMVESEVMKSLGKDGG-------LDDD-DEEEDLDEGSGTKRQSVEVKAH-------------QASHTKYLLMRGYYTVPGMVSTRNLNPNDSIVVNSCQVKFRLRNTPAPTH--LGPTGPTATPLEELQAGPSCLPASFTSLVDPQLHTRCPEEFAHQMAQSGYSPEDVAASLEILQAVAAADCFGVDREKLSRQFSALEKIADKRTRTFLDYIQDLLEQQQVMEVGGN-------TVRLVAMASAQPWLLPSVRLKDVEIDTKASGDDSQSR--------LPAGSSIEDHTSEGAPIPPVSSNGTKKRPYCSIQSPETDAEEATRLPAKKPTLQ----DVCVAASPRPGTEEQTEAQA--QFAAPEDAGAEGPRQESQESVGVS---GLEQLGCEFQLPE----NSEDPRGLTES----NMAQVAWESGCERVCFVGRPWRGVDGRLNMPVCKGMMEAVLYHIMSRPGVPESCLLQYYQGVLQPVAVLELLRGLESLGCIQKRMLKKPASVSLFSRPVVEGLGQASEAEALSCQGSTVTFYEPTLDCTIRLGRVFPHDINWKQSGSIYRCVPGQQRSLCPCLIVPPGLSQEPRPSHSCYQSSAQPSTGVATSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K284-1", "uniprot_id": "TF3C1_MOUSE", "id": "Q8K284-1", "name": "General transcription factor 3C polypeptide 1", "aln": "------MDALESLLDEVALEGLDGLCLPALWSRLESRSPAFPLPLEPYTQEFLWRALATHP--GISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVTLEDVYPIHMILENKDGIQGSCRYFKERKDITSSIRSKCLQPRCTMVEAFSRWGKKLIIVASQDMRYRALIGLEGDPDLKLPDFSYCILERLGRSRWQGELQR-DLHTTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHVDRRSKYDILMEKLSMMLSTRSNQIETLGKLREELGLCERTFKRLYQYMLNAGLAKVVSLPLQEIHPECGPCKTKKGTDVMVRCLKLLKEFKRKMEDDHDDDDDEEVISKGVPPVDIVFERDMLTQTYELIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYAREKARGELLTTVSLASVQDESLMPEGEEAFLSDSESEEESSCSGGKRRGRGSRGHARASGDAGSGSRPHHSTPAKGGWKVLNLHPLKKPK----AAAEERSRRSSACRDG-LDTSSSSELNAPFDPHSMDSHSGDIAVIEEVRLDNPKEGGGSQKGGRHGSSQDKPHKTYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIIRLVRNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKVPPAPAPQEEAEEENQEPEVPSRSANSDPNTSSKPESTRVKKTDEKMGITPLKNYKPVIVPGLGRSIGFLPKMPRLKAMHLFLWYLVYGHPAGHTGEQPALHSERKTGKQESSRPGAQPSS-GDDWDTS---EAKNNTESSSWESEMELSTEIVYVDEISWMRYVPPIPIHRDFGFGWALVSDILLCLPLSIFVQLVQVSYKVDN-LEDFLNDPLKKHTLIRFLPRHIRQQLLYKRRYIFSVVENLQRLCYMGLLQFGPTEKFQDKDQVFVFLKKNAVIVDTTICDPH-YNLAHSSRPFERRLYVLDSMQDVECYWFDLQCICLNTPLGVVRCPCAQKICP-DPGSDPEGSLRKEQESAMDKHNLERKCAMLEYTTGSREVVDEGLVPGDGLGAAGLDSSFYAHLKRNWVWTSYIINKARK-NNTSENGLTGRLQTFLSKRPMPLGSGGSGRLPLWSEGRADAELCADKEEQFELDREPTPGRNRKVRGGKSQKRKRLKKEPIRKTKRRRRGEHPEAKSKKLRYQDEADQNALRMMTRLRVSWSMQEDGLLMLCRIASNVLNT-KVKGPFVTWQVVRDILHATFEESLDKTSHSVGRRARYIVKNPQAF---------MNYKVCLAEVYQDKALVGDFMSRKGNYEDPKVCAKEFKEFVEKLKEKFS--SGLRNPNLEIPNTLQELFAKYRVLAIGDEKDRVRKEDELNSVEDIHFLVLQNLIQSTLSLSNSQSNSCQSFQIFRLYREFREPVLVRAFMECQKRSLVNRRRVSHSQGPKKNRAVPFVPMSYQLSQSYYKLFTWRFPTTICTESFQFYDRLRTNGMLDQPD-HFSFKDLDSSDPSNDLVAFSLDSPGGHCVTALALFSLGLLSVDVRIPEQIVVVDSSMVESEVMKSLGKDGG-------LDDD-EEEEDLDEGSGTKRQGVEVKAH-------------QASHTKYLLMRGYYTVPGMVSTRNLNPNDSIVVNSCQVKFRLRNTPASTQ--LGPTGFTATPLEELQAGLSCLPASFTSLVDPQLRTHCPEEFAHQMAQSGYSPEDVAASLEILQAVAAADCFGIDKEKLSRQFSALEKIADRRTRTFLDYIQDLLEQEQVMEVGGN-------TVRLVTMASAQPWLLHSMRLRDMEVDTKASGDDSQSR--------LPEGPSIEDHTSEGAAVPPVSSHSTKKRPHC----PETDAEEATRLPAKKPTLQ----DVRVAASPRPGAEEQAEAQAPAQLAAPEDADAGGPRQENQENVGVS---GLEQLGCEFQLPE----GSEDPRGLTES----NMAQAAWESGCERVCFVGRPWRGVDGHLNMPVCKGMLEAVLYHIMSRPGVPESCLLQYYQGVLQPVAVLELLRGLESLGCIQKRTLRKPASVSLFSRPVVEGLGQASEAEALSCHESTVTFYEPTLDCTIRLGRVFPHDINWNKWIHL----------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12789-2", "uniprot_id": "TF3C1_HUMAN", "id": "Q12789-2", "name": "General transcription factor 3C polypeptide 1", "aln": "------MDALESLLDEVALEGLDGLCLPALWSRLETRVPPFPLPLEPCTQEFLWRALATHP--GISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVALEDVYPIHMILENKDGIQGSCRYFKERKNITNDIRTKSLQPRCTMVEAFDRWGKKLIIVASQAMRYRALIGQEGDPDLKLPDFSYCILERLGRSRWQGELQR-DLHTTAFKVDAGKLHYHRKILNKNGLITMQSHVIRLPTGAQQHSILLLLNRFHVDRRSKYDILMEKLSVMLSTRTNHIETLGKLREELGLCERTFKRLYQYMLNAGLAKVVSLRLQEIHPECGPCKTKKGTDVMVRCLKLLKEFKR---NDHDDDEDEEVISKTVPPVDIVFERDMLTQTYDLIERRGTKGISQAEIRVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYQREKARSELLTTVSLASMQEESLLPEGEDTFLSESDSEEERSSSK--RRGRGSQKDTRASANLRPKTQPHHSTPTKGGWKVVNLHPLKKQPPSFPGAAEERACQSLASRDSLLDTSSVSEPNVSFVSHCADSNSGDIAVIEEVRMENPKESSSSLKTGRHSSGQDKPHETYRLLKRRNLIIEAVTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIVRLVRNLSEEGLLRLYRTTVIQDGIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKTSQPPVPQGEAEEDSQGKEGPSGSGDSQLSASSRSESGRMKKSDNKMGITPLRNYHPIVVPGLGRSLGFLPKMPRLRVVHMFLWYLIYGHPASNTVEKPSFISERRTIKQESGRAGVRPSSSGSAWEACSEAPSKGSQDGVTWEAEVELATETVYVDDASWMRYIPPIPVHRDFGFGWALVSDILLCLPLSIFIQIVQVSYKVDN-LEEFLNDPLKKHTLIRFLPRPIRQQLLYKRRYIFSVVENLQRLCYMGLLQFGPTEKFQDKDQVFIFLKKNAVIVDTTICDPH-YNLARSSRPFERRLYVLNSMQDVENYWFDLQCVCLNTPLGVVRCPRVRKNSSTDQGSDEEGSLQKEQESAMDKHNLERKCAMLEYTTGSREVVDEGLIPGDGLGAAGLDSSFYGHLKRNWIWTSYIINQAKKENTAAENGLTVRLQTFLSKRPMPLSARGNSRLNIWGEARVGSELCAGWEEQFEVDREPSLDRNRRVRGGKSQKRKRLKKDPGKKIKRKKKGEFPGEKSKRLRYHDEADQSALQRMTRLRVTWSMQEDGLLVLCRIASNVLNT-KVKGPFVTWQVVRDILHATFEESLDKTSHSVGRRARYIVKNPQAY---------LNYKVCLAEVYQDKALVGDFMNRRGDYDDPKVCANEFKEFVEKLKEKFS--SALRNSNLEIPDTLQELFARYRVLAIGDEKDQTRKEDELNSVDDIHFLVLQNLIQSTLALSDSQMKSYQSFQTFRLYREYKDHVLVKAFMECQKRSLVNRRRVNHTLGPKKNRALPFVPMSYQLSQTYYRIFTWRFPSTICTESFQFLDRMRAAGKLDQPD-RFSFKDQDNNEPTNDMVAFSLDGPGGNCVAVLTLFSLGLISVDVRIPEQIIVVDSSMVENEVIKSLGKDGS-------LEDDEDEEDDLDEGVGGKRRSMEVKPA-------------QASHTNYLLMRGYYS-PGIVSTRNLNPNDSIVVNSCQMKFQLRCTPVPAR--LRP---AAAPLEELTMGTSCLPDTFTKLINPQENTCSLEEFVLQLELSGYSPEDLTAALEILEAIIATGCFGIDKEELRRRFSALEKAGGGRTRTFADCIQALLEQHQVLEVGGN-------TARLVAMGSAWPWLLHSVRLKDRE-DADIQREDPQAR--------PLEGSSSEDSPPEGQAPPSHSPRGTKRRASWASENGETDAEGTQMTPAKRPALQ----DSNLAPSLGPGAEDGAEAQAPSPPPALEDTAAAGAAQEDQEGVGEFSSPGQEQLSGQAQPPE----GSEDPRGFTESFGAANISQAARERDCESVCFIGRPWRVVDGHLNLPVCKGMMEAMLYHIMTRPGIPESSLLRHYQGVLQPVAVLELLQGLESLGCIRKRWLRKPRPVSLFSTPVVEEVEVPSSLD-----ESPMAFYEPTLDCTLRLGRVFPHEVNWNKWIHL----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJY7-1", "uniprot_id": "Q9VJY7_DROME", "id": "Q9VJY7-1", "name": "", "aln": "MSASSGGSWINAIYDEVALEGLEGVTLPYLWDLLARRLEFFPSPLPDRIREQTWTLLLRTPPHKIEFFELPAERPLMPYYDRLNDIDEQLGLPVVP--EQCPYMLFPAAYVQEGD--IKGNCNDFKTRKLIPSSD-----LHSLNAAQATEQWAGRLVVVASQELRETALTPESLLMPKNLPLPNYIFLEAIGRSRYSGHTTAGPWSLINYSKDTGILFYIKNKLINLQLIIAQN-YNEINKGRILVSSLLMLPRFYRIYKNHSQENLEKLYLGIMRTPSRQVPVTEITDLLGRPTNFKTKKLLVTHSFRKFFETKQVERPVAPLTKSGKQSKATTRKVTVIQLRNPDMQLKDLYKNDDSEDNQVSEFLDLGHCFLDMPPEEEVFRAVARFGKRGLNSNELCHYTGINATYMRHFVKRVKKHGLVKEYSEQVGKSRQFRFVAVGHLG--DLSKEDEIKKKALEIR-------CKDEPNITESTDVLLKD-------------------------------------------------------------------------------------------LPEIVTNARPIAFKIKKTRAAN---------------------QTQRQINRQKMIVRQIDQNCLVS-LPRVLRSVQETERQAGFKDSLCRRSLMRLLRPMVEENIINVFEITLHYNQRVRVYRFATHPKIGLDHAVMKREIVKLKSNFH-LITEERMKRPSQMAPKERKEVLARRKLAPERS-----------------------------------------NAVFKTQAPKLLLARTLHEFLYYLHHELSPEQKPLPMSAELVQQWQKSEPALQPRQFFDEWQAD-------------------ETKVQPYTEDIGWRTFIPPLPRYVDKPSGWLYFMDAMDRMPLSLFMRICRIEREANDDLRLQLQHPIRQHYLLSQLK---LETIVPRLKLQQIYVGTLRLLNNMGLIQVSEQKLGRDSLHRWVFLNQRTSLLDTTSSTEHNYMQVSADRSYTKLNFEFSSVEQLGNYWAKLQHICIYTKLGYRKSLSTQRILP---------------------ARLKVLVFQPTVEFDQAVELDNGTVPGDHLGAAGLSSHLFAHQFRHWSWVQ-------RQNGGKSNAAREKAKRTVRKR---------------------------------------------------AVITRLKIGPRLAVRKARELSTGKTLKKSSGPRDDIDRDALRNMRTLRVKWAPEEDRLLKMGRAVYMFIDAPTMTLALCDLAVVCRDLIRRWLGICNKTTQACVRRVQFMVKMKRDIPDVPSWIYAMQTQPQFNTVYNERFLSQLKRDYPNKTDFQNALMTHFALMMAKLQRMIAKSQGSVSRQFLLPDTLEAFGSQLRECRSAHEEQQLLFQDPAS-ETDLQVAVAHGVLHSNICCAKD--KTLLNLQTFEIYKHFSEEVLNSAFNKARADSLLVAVKRRNIQSAASRQIS--GPGHLLSSKYKYRLIYTKLTHFLYDCFFALDQKLRADQEQQLSSPHFGQLLVMGEWLSENRLSLSLQLPTNILTVDTTTVGRQSGCNSDRILDHYSCIFDNAPQTEYSKRLEGECSGRQASRVLFHPANLSFRLPTSAYNQLSKLQLRAMHFFCALDALGEAITISQSRLEQFDCPFTNCIMRSGNYLNAVERIAHEQRPILRQLVADALPSQQFVLESHPAGTPLTVTNANLLPFAQQLEAFWREKQQAMELKDLGKTLAER--TQHKLTDWRSICAELLDDEPHAWETERVQEYEPALNKEERARAQDVFVVHLPTIGIKVVEQPEGKQTIDSLRTSVLDKVLKTTYWQYTENSFESLRPKLQESGYDDRAIRHMEDILYHIEKHTLGVKGLELRKIFPLGDFLLETLHLLADHNLIKRVGIVSVMYVHKNHIRNWVVHTFHIKRLEREKVQPMVAAAPGTLQAVVGHKRKLEAQETSSSVPEKRVKLMEQLSTESESDEPGGSASKRPKRITRKEPSLEVANATLEATRDAIAMRPQPWIRVNASLNRRVLDRWLGAVLSECIARVGCTVHSLFLRFL-HLVPVDVMFLLELLHDLGCIQLMEMR---PHKVHVESLLDDEHEDGDEQPVTELYDPMQTYVQVHGNAIGRLTNFIGLKKYSTEFI-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :::: ********:*: ** **. * * ** ** :* * * * *.*:* * *** : ** ::** : *: ::* : *.. *:*.*. ** ** *... . .:* .:*. :*::**** :* ** . :** .* :** :****:.*. :. *:* *.* :: * : ** *. .: .* * **:* **: :.: : :*** : : ..: .: :: : ** . .: . .. : : * . * .*.* * ::* : : ::**.::: :*: : . .:: :.: : * *.:*:.. *: .:. * : : :::. :** : *: *:.* :::: . ***:: :* *: ::*. :.*. :.:*.: .. . *::.* * :* * ::*:::*:. : : *:. * : : : : *:* *.. . *::*::**:* : **.::.::. *: : : :..**.:. :..::: * ::: .: * :*:* . .*: . * : *. * . * .: *:* : : :* * * . ::* * . . : : .... :* . . *:: :. *.:: .* ::**:* : * ** . * : :***:*::: ::. :.:: *. *:.*:::* *: * : :: : : * .*: * ***:*.. : :*. : ::**::.: ::*** . * * . :.*.: : : :.*:::: ** .** :*: * ** :. .:: . .*: .. :*:* :*** ******.* ::.* *:* *.. : * .*. : : : ** .*** * :: :. . .* :*: *:.**: * ***.*: :** ** : * . .::: .:. .: ** * : :**::: **.:::** : :: : : **::: * . .. : :. ..* :: **:. :: .. . :: :*:**: : :: * ..*::: :* . *::. * :.:::*.:. :.. :: .:* *.:*:.: : ** ** :.: **: : : .. ..: * *: *::: ::. : * : :::*: : .. :*. .. :.: :::**: * . .. : .. . . ** :: : .. :.* * * : . * . : . * . : ::::. *::. : :: : * . **. : *. :. : :* . .:: : :.:** . :. : : : .: ::: : : ..:: .* : .. : *.: . .**:* *:: . : . * : *: * * : .: * . :.. . . . . * :: : * . . : . . . .:: :: . : * * * . ** ...* ***. : : * *: *: :*.. ::::.: * : :.: :** *:. ** * . : *:* . ::* * . .*: : * ** *: **. *..****: :: . .:. .::: .. : ..: * . . :: * ::. ", "identical_positions": 344, "similar_positions": 642, "identity": "15.36%" }, { "cls_id": "homologset.agr.RGD:621050", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P13224-1", "uniprot_id": "GP1BB_HUMAN", "id": "P13224-1", "name": "Platelet glycoprotein Ib beta chain", "aln": "--------------------------MGSGPRG------------ALSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCVAPPALRGRLLPYLAEDELRAACAPGPLCWGALAAQLALLGLGLLHALLLVLLLCRLRRLR-ARARARAAARLSLTDPLVAERAGT-----DES-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56400-1", "uniprot_id": "GP1BB_MOUSE", "id": "P56400-1", "name": "Platelet glycoprotein Ib beta chain", "aln": "--------------------------MGSRPRG------------ALSLLLLLLALLSRPASGCPAPCSCAGTLVDCGRRGLTWASLPAAFPPDTTELVLTGNNLTALPPGLLDALPALRAAHLGANPWRCDCRLLPLRAWLAGRPERAPYRDLRCVAPPALRGRLLPYVAEDELRAACAPGLLCWGALVAQLALLVLGLLHALLLALLLGRLRRLR-ARARARSIQEFSLTAPLVAESARG-----GAS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJM7-1", "uniprot_id": "GP1BB_RAT", "id": "Q9JJM7-1", "name": "Platelet glycoprotein Ib beta chain", "aln": "--------------------------MGSRPRG------------ALSLLLLLLAPPSRPASGCPAPCRCSETRVDCGRRGLTWASLPAAFPPDTTELVLTDNNLTALPPGLLDTLPALRRVHLGANPWRCDCRLLPLRAWLAGRPEREFYRDLRCVAPLALRGRLLPYVAEDELRAACAPGLLCWGALVAQLALLVLGLLHALLLALLLSRLRRLR-AQARARSTREFSLTAPLVAESAGG-----GAS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32U0D4-1", "uniprot_id": "A0AB32U0D4_DANRE", "id": "A0AB32U0D4-1", "name": "", "aln": "MAPKKATYCNNTPVVLKVGGRDPPKRLGDNEGGSPVCVCVCAGMRSVVLVFFLSAMAAVVQGSCPHVCSCSAGVVDCSNRALTTATLPSSFPASTTELLLNENHLTALPTGLLDALPALRRVALHGNSWACDCAILYLRGWMLKRGSDPSMRNVSCSSPAHLRGRLIVYLPEQELLDSCR-YWLCNLALASQISLLVFIGVQALLLASVIFFLRRFERLTEEAQRTAAESFTAEENADHNSEYVMLKDRSM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. * :: *:::* * : ..** * *: ***..*.** *:**::** .****:*. *:*****.****:***** . * .*.* *** :: **.*: * . *:: * :* *****: *:.*:** :* ** **.:*::** : ::****. :: ***:. .*: *:* *: . * ", "identical_positions": 82, "similar_positions": 56, "identity": "32.67%" }, { "cls_id": "homologset.agr.RGD:621052", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAA7-1", "uniprot_id": "F1MAA7_RAT", "id": "F1MAA7-1", "name": "Laminin subunit gamma-1", "aln": "-MTGGRRAALALQLQRRLWLLLAVLAAVAC--WVRAAMD----------------ECADEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPE-EYCVQTGVTGVTKSCHLCDAGQLHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPNSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECVKN----EFGKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESANQCLPCDCNGRSQECYFDPELYRSTGHGGHCTNCRDNTDGAKCERCRENFFRLGNTEACSPCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGS---TDECNVETGRCVCKDNVEGFSCERCKPGFFNLESSNPKGCTPCFCFGHSSVCTNAVGYSVYDISSTFQIDEDGWRVEQRDGSEASLEWSSDRQDIAVISDTYFPRYFVAPAKFLGNQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYIFRLHEATDYPWRPALSPFEFQKLLNNLTSIKIRGTYSERSAGYLDDVTLQSARPGP-GVPATWVESCTCPVGYGGQFCETCLPGYRRETPSLGPYSPCVLCTCNGHSETCDPETGVCDCRDNTAGPHCEKCSDGYYGDSTLGTSSDCQPCPCPGGSSCAIVPKTKEVVCTHCPTGTAGKRCELCDDGYFGDPLGSNGPVRLCRPCQCNDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKEGFFGNPLAPNPADKCKACACNPYGTVQQQ---SSCNPVTGQCQCLPHVSGRDCGACDPGFYNLQSGQGCESCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCETNHFGFGPEGCKPCDCHHEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVAEHRVKLQELESLIANLGTGDETVTDQAFEDRLKEAEREVTDLLREAQEVK-DVDQNLMDRLQRVNNSLHSQISRLHNIRNTIEETGILAERARSRVESTEQLIEIASRELEKAK--------MAAANVSITQPESTGEPNNMTLLAEEARRLAERHKQEADDIVRVAKTANETSAEAYNLLLRTLAGENQTALEI-EELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLTP--VDSEALESEANKIKKEAADLDRLIDQKLKDYEDLREDMRGKEHEVKNLLEKGKAEQQTADQLLARADAAKALAEEAAKKGRNTLQEANDILNNLKDFDRRVNDNKTAAEEALRRIPAINRTIAEANEKTREAQLALGNAAADATEAKNKAHEAER-IASGVQKNATSTKADAERTFSEVTDLDNEVNGMLRQLEEAENELKRKQDDADQDMMMAGMASQAAQEAELNARKAKNSVSSLLSQLTDLLEQLGQLDTVDLNKLNEIEGSLNKAKDEMKVSDLDRKVSNLENEARKQEAAILDYDRDIAEIIKDIHNLEDIKKTLPTGCFNTPSIEKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02468-1", "uniprot_id": "LAMC1_MOUSE", "id": "P02468-1", "name": "Laminin subunit gamma-1", "aln": "-MTGGGRAALALQPRGRLWPLLAVLAAVAG--CVRAAMD----------------ECADEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPE-EYCVQTGVTGVTKSCHLCDAGQQHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPNSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNEPKVLKSYYYAISDFAVGGRCKCNGHASECVKN----EFDKLMCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASESLPCDCNGRSQECYFDPELYRSTGHGGHCTNCRDNTDGAKCERCRENFFRLGNTEACSPCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDLRGS---TDECNVETGRCVCKDNVEGFNCERCKPGFFNLESSNPKGCTPCFCFGHSSVCTNAVGYSVYDISSTFQIDEDGWRVEQRDGSEASLEWSSDRQDIAVISDSYFPRYFIAPVKFLGNQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYIFRLHEATDYPWRPALSPFEFQKLLNNLTSIKIRGTYSERTAGYLDDVTLQSARPGP-GVPATWVESCTCPVGYGGQFCETCLPGYRRETPSLGPYSPCVLCTCNGHSETCDPETGVCDCRDNTAGPHCEKCSDGYYGDSTLGTSSDCQPCPCPGGSSCAIVPKTKEVVCTHCPTGTAGKRCELCDDGYFGDPLGSNGPVRLCRPCQCNDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKEGFFGNPLAPNPADKCKACACNPYGTVQQQ---SSCNPVTGQCQCLPHVSGRDCGTCDPGYYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCETNHFGFGPEGCKPCDCHHEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKAAEHRVKLQELESLIANLGTGDDMVTDQAFEDRLKEAEREVTDLLREAQEVK-DVDQNLMDRLQRVNSSLHSQISRLQNIRNTIEETGILAERARSRVESTEQLIEIASRELEKAK--------MAAANVSITQPESTGEPNNMTLLAEEARRLAERHKQEADDIVRVAKTANETSAEAYNLLLRTLAGENQTALEI-EELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLTP--VDSEALENEANKIKKEAADLDRLIDQKLKDYEDLREDMRGKEHEVKNLLEKGKAEQQTADQLLARADAAKALAEEAAKKGRSTLQEANDILNNLKDFDRRVNDNKTAAEEALRRIPAINRTIAEANEKTREAQLALGNAAADATEAKNKAHEAER-IASAVQKNATSTKADAERTFGEVTDLDNEVNGMLRQLEEAENELKRKQDDADQDMMMAGMASQAAQEAELNARKAKNSVSSLLSQLNNLLDQLGQLDTVDLNKLNEIEGSLNKAKDEMKASDLDRKVSDLESEARKQEAAIMDYNRDIAEIIKDIHNLEDIKKTLPTGCFNTPSIEKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11047-1", "uniprot_id": "LAMC1_HUMAN", "id": "P11047-1", "name": "Laminin subunit gamma-1", "aln": "-MRGSHRAAPALRPRGRLWPVLAVLAAAAAAGCAQAAMD----------------ECTDEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPE-EYCVQTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECMKN----EFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGS---IDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYFPRYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGYLDDVTLASARPGP-GVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQ---SSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVADHRVKLQELESLIANLGTGDEMVTDQAFEDRLKEAEREVMDLLREAQDVK-DVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTERLIEIASRELEKAK--------VAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEI-EELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSP--LDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAER-IASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAKKQEAAIMDYNRDIEEIMKDIRNLEDIRKTLPSGCFNTPSIEKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVF0-1", "uniprot_id": "LAMC1_DANRE", "id": "Q1LVF0-1", "name": "Laminin subunit gamma-1", "aln": "---------MSLFSCLLLWTLWAA--------CSHGAMD----------------ECIDEDDRPQRCMPEFVNAAFNATVVATNTCGSPPE-EFCVQTGVTGVTKSCHICNAADPRLHHGAVYLTDYNQPVQPTWWQSQTMLAGIQYPNSINLTLHLGKSFDITYVRLKFHTSRPESFAIYKRSSEDGPWTPYQYYSGSCEKTYSKNNRGFIRTGEDEQQALCTDEFSDISPLYGGNVAFSTLEGRPSAYNFDNSPVLQDWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECVKN----EYSKLVCNCKHNTEGADCNVCKPFYNDRPWRRATAENPNECLPCNCNGKSAECYFDPELYRATGHGGHCRNCADNTDGPKCERCLANYYREASGQRCLSCGCNPVGSLSTQCDNTGRCSCKPGVMGDKCDRCQPGYHSLSEAGCRPCSCNPAGS---TQECDVQTGRCQCKENVDGFNCDRCKLGYFNLDPQNPQGCTPCFCFQHSTVCESADGYSVHKITSTFDRDDEGWKGKQRDDSSVPVQWSPSSGEISLISEDYFPIYFVAPDKFLHNQLLSYGQNLTLNFRIQRHDARLSAEDVVLEGSGLRVAVPLIAQGNSYPGEETQTFVFRLHDTTDYPWRPTIKHADFQKLLYNLTSIMIRGTYSAQSAGYLDNVSLVTARRGP-GTPARWVEKCTCPQGYLGQHCEQCDQGFRRSRPELRRFSTCERCNCNGHSDTCDPETGMCNCQHNTAGLSCERCKDGFYGDSTVGSSSDCKACPCPAGATCAVVPKTNEVVCTNCPTGTTGKRCELCDDGFFGDPLGEKGPVRACRACSCNNNIDPNAVGNCNRESGECLKCIYNTAGVFCDRCKQGFYGDARAANVADKCKPCKCSPYGTVDRQ---TACSQVTGQCPCLPHVINRDCGACELGFYNLQSGKGCERCNCNPIGSTNGQCDIVSGQCECQPGVTGQHCERCEVNFFGFSSSGCKPCDCDPEGSESAQCKEDGRCHCRPGFVGSRCDMCEENYFYNRSTPGCQQCPNCYSLVRDKVNQQRQKLLDLQNLIDSLDNTETTVSDKAFEDRLKEAEKTIMDLLEEAQASK-EVDKGLLDRLNNINKTLNNQWNRLQNIKNTVDNTGAQADRARNRVRDAENLINTAREELDKAK--------EAISKVDIKIPTTSGDPNNMTLLAEEARKLSEKHKADADQIEKIAKDANDTSTKAYNMLKKALDGENKTSSDI-DELNRKYLEAKDLAKNLEKQAAKVHAEAEEAGNKALKIYANLTSLPP--INTKTLEDDANKIKKEASDLDKLIDKTEKEYNDLREDLRGKETEVRKLLDKGKTEQQTADQLLARADAAKALAEEAAKKGKSTFQEAQDILNNLRDFDKRVNDNKTAAEDAMRRIPQINATINEANDKTRRAEAALGNAAADAKDAKAKAEEAEK-IANDVQKGSAKTKADAEKAFEDTMKLDKDVDKMMDQLTAAEKELEKKKAEADTDMMMASMASDNAKDAEGNARKAKSAVREVLNTINALLGQLGNIDKVDLSKLNQIDNALKDAKDKMAGSELDRKLKELNDIAKSQEDMISDYDRQIQEIRADIANLNDIKNTLPEGCFNTPSLERP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15215-1", "uniprot_id": "LAMC1_DROME", "id": "P15215-1", "name": "Laminin subunit gamma-1", "aln": "MKRSRWSHSGSSTARLLLIGVLFASCSTAILGAQRPPINSAGGHELRGTTFMPALECYDPYGRPQKCLPEFINAAYQLQIESTNTCGEQNDNHFCIQT-MNQNHKNCEFCKYN----DHNPSFLTDLHDPQSPTWWQSETMFEGIQHPNYVNLTLHLGKSYDITYVRILFRSPRPESFTIYKRTSESGPWIPYQFYSATCRDTYSLPDSRAIRKGEGEAHALCTSEYSDISPLRDGEIAFSTLEGRPSGINFERSGELQEWVTATDIRITLDRLNTFGDELFGDSQVLKSYFYAISDIAVGARCKCNGHASKCVPSTGMHGERTLVCECRHNTDGPDCDRCLPLYNDLKWKRSTSTEVNECKACNCNGLADKCFFDANLFNRTGHGGHCLDCRENRDGPNCERCKENFYMRDDG-YCVNCACDPVGSRSLQCNSHGKCQCKPGVTGDKCDRCDNNYYQFGPHGCQQCGCDSGGSHQNTPACDTETGICFCKENVEGRRCNECKPGFFNLDKNNRFGCTPCFCYGHTSECMTAPGYSIVSVTSNFNKFKERWTAADLNQREVDIKYNQYSRSIGTTAQGNEHVYFQAPDRFLGDQRASYNRDLKFKLQLVGQVANTGVSDVILEGAGSRISLPIFAQGNGIPDQGVKEYTFRLHEHHDYQWQPSQSARGFLSILSNLTAIKIRATYSVQGEAILDDVELQTAHRGAAGHPATWIEQCTCPEGYLGQFCESCAPGYRHSPARGGPFMPCIPCDCHGHADICDSETGRCICQHNTHGDNCDQCAKGFYGNALGGTPNDCKRCPCPNDGACLQIN-EDTVICTECPKGYFGSRCEQCSDGFFGDPTGLLGEVQTCKSCDCNGNVDPNAVGNCNRTTGECLKCIHNTAGEHCDQCLSGHFGDPLAL-PHGRCDRCSCYEAGTEQDEQSITRCDQVTGQCQCKPNVIGRDCGECQPGYFNIRSGNGCENCLCDPVGSYNSTCDRYSGQCHCRPGVMGQRCDQCENYFYGFSSEGCKPCECDESGSKGFQCDQNGQCPCNDNVEGRRCDRCKEN-KYDRHR-GCIDCPDCYNLVQDAADLHRAKLFNLSQTLDEIAR-TPVTNDDEFEAKLKAVQEKVAVLAQDARDNSGDGGQTYAEVIDDLHKHLDSVREHLVSADKFQADANGEIDRARQNYTILDQITENAKKELQQALDLLNDEGAQALARAKEKSVEFGQQSEQISDISREARALADKLESEAQFDLKNAKDAKDAVEKAHQLAKSAIDLQLKIGTELRSEVGLELSHVKQSLGTVVQTSKEALRKANEVYDTALTLLNDVNRQTQPEIDISQLKKDAVAANERADELLKQITELSNSNGELFADFETEQELTEALLKRAEQQQLEDIELLERAKAAHDKATKAVEQGDNTLKEANNTYEKLAGFQSDVQRSSESAEKALQTVPNIEKEIQNAESLISQAEEALDGANKNANEAKKNAQEAQLKYAEQASKDAELIRRKANETKVAARNLREEADQLNHRVKLTEMDIFKLEESSTKDDNLVDDAKRKVGQAKADTQEAQKQIEKANADLTAIKDELENLKDINTGDLDRLENRLATVEGEINRVNLTGRIEKYREQRTIQKNLIDKYDAELRELKDEVQNIGLISKALPDSCFSRNRLEP-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . : .:: ** * .***:*:***:***:: : :***** : .:*:** :. *.*.:*. .*.. :*** :: ..*****:**: *:*:*. :********::******: *::.*****:****: *.*** ***:**.:*..*** : **.* .* :****.*:****** .*::**********. **:.* **:********:**:********:*.:.:*****:*****:***.*********:*: . .*:*:*:*** * **: * *::** *:*:*: . .:. .*:*** : :*:**.:*:. ******* :* :* **.:**** *:: . * * *.**** * **:. *:*.***** *******: .::.: **: *.*: ** *: :** * **:**:* *:.** *:***: .* *******: *:: * .* ***: .::*.*: .: * : : .. :::. .*. :: ** ** :** .* **.::*.:.::: : :. ...*::***:* *:::*::****. *.: . : ****: ** *:*: . * .:* ***:* **.*** : . **:* * :*: *. * ** *:*.**** ** **.** * *:*:. . : .* * *:**:: **.*** * *:.** * *::* .*:**:: *:..**: **** ..:* : . *:**.**.* *.*** *.**:**** * * *: *: *.*..*:********** :*******:**** .**:* .*.:*:. * .:*. * * ** . : : *. ***** * *:* .:*** *: *::*::**:*** * *..:** *. ** :***.*:**: **:*::** .:**...*****:*. .** . **.::*:* *. .. * *** *:** *:* ** :** ** **:* . :* ** :*.. : .: ..*. ** :** .:. : * .:*: . : .: : :: ::. * . .:* . : ::. ::** . :.: : * .**::* * :... . :.:::: ::.*** *::: : :*: : ** *::: :*::: :: : : . :: .*:. : ..*: : : : .. :*:.. :.*: : .: . :: . *:.:* : .* :* : * : :. :* *:. :: .. **.:.: :* :** **.**: * :*.::* .*::**:: ::* .*: *: .. :**.*:: :* *: * :*:. .*: **..* :*.:** :*.**: *. ..*.: : .*:.: . .* ::.: : :: :* :: : : .: * :.. *. . :*: ::::*:. : . :. : :* ::. :: ..*:.::. * .:.:: :* ::.. .. *: * .*: :: *: :: *: * ::** .**. :* ", "identical_positions": 572, "similar_positions": 549, "identity": "34.65%" }, { "cls_id": "homologset.agr.RGD:621053", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LM30-1", "uniprot_id": "A0ABK0LM30_RAT", "id": "A0ABK0LM30-1", "name": "Laminin subunit gamma-2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKVETDLGALELFGGLNTCAT--VCDCNGKSRQCVFDQELHRQTGNGFRCLNCNDNTAGVHCERCREGFYRQRDRDRCLPCNCHSKGSLGAGCDNSGQCRCKPGVVGQRCDRCQPGFHMLTDAGCTRDQRQLDSKCDCDPAGISGPCDSGRCVCKPAVTGERCDRCRAGYYHLDRANPEGCTQCFCYGHSDSCHTSADFSVHKITSTFNQDEDGWKAVQRNWA---PAKLHWSPRHQDVFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAYDVILEGAGLQIRAPLMPPGKTLPCGITKTYTFRLNEHPSSHWSPQLSYFEYRRLLRNLTALLIRATYGEYSTGYIDNVTLISARP-VSGAPAPWVERCVCPAGYKGQFCQECASGYKRDSARLGPFGTCVPCNCQGGG-ACDPDTGDCYSGDENPDIECADCPIGFYNDPHD--PRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGFFGDPFGERGPVRPCQRCQCNNNVDPSASGNCDQLTGRCLKCIYNTAGIYCDQCKAGYFGDPLAP-----------------------------------------------------------------------------------------------------NPADKCRACNCNPVGSEPGECRSDGSCVCKPGFGGLNCAHA--------AALTSCPACYNQVKTQMDQFAQQLQNLEALVSKAQGGNG-AVPSEELEGRMQQAEQALRDILREAQISEG------AMRALSLQLAKARSQENNYKNRLDDLKMTVERIRALGSQYQNRVQDTSRLISQMRLSLAES-EASLQNTNIHSSEHYVGPNGFKSLAQEAARLADSHVESANTMKQLTRETEDYSKQALSLARKALSG--GGGSGVLDSSVVQGLMGKLEKTKSLTQQLSREGTQADIEADRSYQHSLRLLDSAS-QLQGIRDSSFQA-EAKRIRQKADSLSNLVTKQMDAFTSVRNNLGNWEKETRQLLQTGKDRRQTSDQLLSRANLAKSRAQEALSMGNATFYEVENILKNLREFDLQVEDRKAEAEEAMKRLSYISQKVADASDKTQQAETALGSATADTQRAKNAATEALEITSEIEQEIGSLN-LEANVTADGALAMEKGLATLKSEMREVEGELARKELEFHTDKDSLQLVITEAQQADARAKSTGVTIQDTLNTLEGILRLIDQPDAVDEEGLMLLEQELFQAKTQIN-SRLRPLMSELEDRARRQSNHLHLLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61092-1", "uniprot_id": "LAMC2_MOUSE", "id": "Q61092-1", "name": "Laminin subunit gamma-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPALWLSCCLGVALLLPAAQATSRREVCDCNGKSRQCVFDQELHRQTGSGFRCLNCNDNTAGVHCERCREGFYRHRDRDRCLPCNCHSKGSLSAGCDNSGQCRCKPGVTGQRCDRCQPGFHMLTDAGCTRDQGQLDSKCDCDPAGISGPCDSGRCVCKPAVTGERCDRCRPGYYHLDRANPEGCTQCFCYGHSASCHASADFSVHKITSTFSQDVDGWKAVQRNGA---PAKLHWSQRHRDVFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRQPSAYDVILEGAGLQIRAPLMAPGKTLPCGITKTYTFRLNEHPSSHWSPQLSYFEYRRLLRNLTALLIRATYGEYSTGYIDNVTLVSARP-VSGAPAPWVERCVCPAGYKGQFCQECASGYKRDSARLGPFGACVPCNCQGGG-ACDPDTGDCYSGDENPDIECADCPIGFYNDPHD--PRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGFFGDPFGERGPVRPCQRCQCNNNVDPNASGNCDQLTGRCLKCIYNTAGVYCDQCKAGYFGDPLAP-----------------------------------------------------------------------------------------------------NPADKCRACNCSPMGSEPGECRGDGSCVCKPGFGGLNCDH---------AALTSCPACYNQVKIQMDQFTQQLQSLEALVSKAQGGGGGGTVPVQLEGRIEQAEQALQDILGEAQISEG------AMRAVAVRLAKARSQENDYKTRLDDLKMTAERIRALGSQHQNRVQDTSRLISQMRLSLAGS-EALLENTNIHSSEHYVGPNDFKSLAQEATRKADSHAESANAMKQLARETEDYSKQALSLARKLLSG--GGGSGSWDSSVVQGLMGKLEKTKSLSQQLSLEGTQADIEADRSYQHSLRLLDSAS-QLQGVSDLSFQV-EAKRIRQKADSLSNLVTRQTDAFTRVRNNLGNWEKETRQLLQTGKDRRQTSDQLLSRANLAKNRAQEALSMGNATFYEVENILKNLREFDLQVEDRKAEAEEAMKRLSSISQKVADASDKTQQAETALGSATADTQRAKNAAREALEISSEIELEIGSLN-LEANVTADGALAMEKGTATLKSEMREMI-ELARKELEFDTDKDTVQLVITEAQQADARATSAGVTIQDTLNTLDGILHLIDQPGSVDEEGMMLLEQGLFQAKTQIN-SRLRPLMSDLEERVRRQRNHLHLLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13753-1", "uniprot_id": "LAMC2_HUMAN", "id": "Q13753-1", "name": "Laminin subunit gamma-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGS---PAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYIDNVTLISARP-VSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG-ACDPDTGDCYSGDENPDIECADCPIGFYNDPHD--PRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAP-----------------------------------------------------------------------------------------------------NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEH----------GAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDG-VVPDTELEGRMQQAEQALQDILRDAQISEG------ASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAES-EASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVS-RLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLN-LEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDGLLHLMDQPLSVDEEGLVLLEQKLSRAKTQIN-SQLRPMMSELEERARQQRGHLHLLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RET4-1", "uniprot_id": "A0A8M1RET4_DANRE", "id": "A0A8M1RET4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWKMKSSWIILCAFCIWTPVHGTVRSSSACSCHGKAR-------FCRADQLGLYCLNCQGNTQGRHCESCKEGYYHQRAGDNCVPCNCNPAGSQGPVCSSNGQCTCKQGIHGDKCDRCHDGSPVTANG--------------CEPLRLR---------------------CWSRNNGRLTYNTEECLPCFCNGHSNVCSSAEGYSVYNITSPFENGPEGWRAATAQGVNPSQVQFRWSPTHKDLEVISKEILPVYLFAPATYLGNRALSYGQTLTFSLRLDRGVRRPSTSDVVLEGAGLKVSASLGDLRTVVPCGKKITYTFRLDEQPGSKWKPQLSSAEFQTLLSNLTAIKIRGTFGENGRGYLDDVSLVSAKL-GPGTPALWVEKCRCPAEYDGHFCEHCATGFRRLIPGQGPRSPCVPCSCQGG--ACDPETGGCYSADEIP--NLQMCPRGYYVNRQL--SNSCQKCPCREGDSCYVIGGTQEVTCTRCPRGTTGSRCEICDDGFYGDPLGEYGPRKQCQPCQCYGHVDQNAVGNCDRRTGQCRKCLNHSTGPNCEYCEAGYHHN---------------------------------------------------------------------------------------------------------YPTEPCQACNCNRQGSVSNSCSDKGQCECKEGYDGLRCEE------------STCPSCFNPVKSKIEVYARQLQEMEDLF-KGFGGNEAPVSDAQMDQAVRAAEVMVRNLESRANELTN------TEKQLQDKLASISRSQLREDRNMEALLTSVNGIRNNDQQYRTEVSEIRKLISDVRSKLQQA-KRDMQEIEIPSGDAVPGSGTLSDLVQRAADLAEQHQGEALTVEGIADNSLAQSEKALDLIRGIINR------ENKVKDEIRDLKREYEADVNKVLDMDRKANQLTDAAGKESGEAQNALQQLS-DLEKKLPKPLTK-EIAGVVSMFDNLKGLVEGNLSQYSDLQQYMLNEQKETGDLLIKAKNFQQIQDELLARANAAEAVKNQSLEIFANNKDSLEKTLETLKGFDDQIGVKKDLADAAISKLPAVNATIQKAIADNMQTQDILDAMADPFRDAQETIDTLTSNVYKLEGMTSSLP-SSS-DILEAASKLKEDVDGLKTEASATRDRLNEEKSKAKAQINEAKNAVVESNGVLENAKKARNAVNDTLQDIADIMSSLGTPGTIDDKRVADLENAITKSRRRVE-DELRPKLRELEAKDAQQRATITGMINDIDTILADIANLEEIHKNIPEGCFNIPPIERP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15215-1", "uniprot_id": "LAMC1_DROME", "id": "P15215-1", "name": "Laminin subunit gamma-1", "aln": "MKRSRWSHSGSSTARLLLIGVLFASCSTAILGAQRPPINSAGGHELRGTTFMPALECYDPYGRPQKCLPEFINAAYQLQIESTNTCGEQNDNHFCIQTMNQNHKNCEFCKYNDHNPSFLTDLHDPQSPTWWQSETMFEGIQHPNYVNLTLHLGKSYDITYVRILFRSPRPESFTIYKRTSESGPWIPYQFYSATCRDTYSLPDSRAIRKGEGEAHALCTSEYSDISPLRDGEIAFSTLEGRPSGINFERSGELQEWVTATDIRITLDRLNTFGDELFGDSQVLKSYFYAISDIAVGARCKCNGHASKCVPSTGMHGERTLVCECRHNTDGPDCDRCLPLYNDLKWKRSTSTEVNECKACNCNGLADKCFFDANLFNRTGHGGHCLDCRENRDGPNCERCKENFYMRDDG-YCVNCACDPVGSRSLQCNSHGKCQCKPGVTGDKCDRCDNNYYQFGPHGCQQCGCDSGGSHQNTPACDT---ETGICFCKENVEGRRCNECKPGFFNLDKNNRFGCTPCFCYGHTSECMTAPGYSIVSVTSNFNKFKERWTAADLNQR---EVDIKYNQYSRSIGTTAQGNEHVYFQAPDRFLGDQRASYNRDLKFKLQLVGQVANTGVSDVILEGAGSRISLPIFAQGNGIPDQGVKEYTFRLHEHHDYQWQPSQSARGFLSILSNLTAIKIRATYSVQGEAILDDVELQTAHRGAAGHPATWIEQCTCPEGYLGQFCESCAPGYRHSPARGGPFMPCIPCDCHGHADICDSETGRCICQHNTHGDNCDQCAKGFYGNALGGTPNDCKRCPCPNDGACLQIN-EDTVICTECPKGYFGSRCEQCSDGFFGDPTGLLGEVQTCKSCDCNGNVDPNAVGNCNRTTGECLKCIHNTAGEHCDQCLSGHFGDPLALPHGRCDRCSCYEAGTEQDEQSITRCDQVTGQCQCKPNVIGRDCGECQPGYFNIRSGNGCENCLCDPVGSYNSTCDRYSGQCHCRPGVMGQRCDQCENYFYGFSSEGCKPCECDESGSKGFQCDQNGQCPCNDNVEGRRCDRCKENKYDRHRGCIDCPDCYNLVQDAADLHRAKLFNLSQTLDEIARTPVTNDDEFEAKLKAVQEKVAVLAQDARDNSGDGGQTYAEVIDDLHKHLDSVREHLVSADKFQADANGEIDRARQNYTILDQITENAKKELQQALDLLNDEGAQALARAKEKSVEFGQQSEQISDISREARALADKLESEAQFDLKNAKDAKDAVEKAHQLAKSAIDLQ-----LKIGTELRSEVGLELSHVKQSLGTVVQTSKEALRKANEVYDTALTLLNDVNRQTQPEIDISQLKKDAVAANERADELLKQITELSNSNGELFADFETEQELTEALLKRAEQQQLEDIELLERAKAAHDKATKAVEQGDNTLKEANNTYEKLAGFQSDVQRSSESAEKALQTVPNIEKEIQNAESLISQAEEALDGANKNANEAKKNAQEAQLKYAEQASKDAELIRRKANETKVAARNLREEADQLNHRVKLTEMDIFKLEESSTKDDNLVDDAKRKVGQAKADTQEAQKQIEKANADLTAIKDELENLKDINTGDLDRLENRLATVEGEINRVNLTGRIEKYREQRTIQKNLIDKYDAELRELKDEVQNIGLISKALPDSCFSRNRLEP-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*.*:* : : . * **:*. * * :** *::.:* : *: * *.. ** . *.. *:* ** *: * :**** . * * . * * *** **: * :: :*: .:** * : : * *. : ..:::. :.: :: **: ** :**:: **.: *.*. :: .... **:***** :: .: . :* *****.*: . :*.*. * : :* ****: **.*:. . . :*:* * :*: .* ** *:*:* ** * *:**: **.*::: . ** .*:**.*:* **.:** * . .: : *. *:* : ...*: *** :. :* : : * *..** * *:*** * **::*** * * : *: *:* .:** .* ***:: **.* **: :::* *: * :*:. : .:: *:.*:*. ** * .* * *: . * .* . ** *:* *: : . :* :. . : : . : : : . . : :* . . : * . : : : : * : . : : : . :..: :.* *:. .* : :: ::* .* : : : : . . : ..: *.. : *:. . : . : . *.* : . : . :: : ** .:. : . :** **: *. :::. . . :. :.* *: :: . *: *:. :. :. : .* *:: *.. . *:: : ..* .: .* :.: *: . : . : . : : . . : . : .: ::.: : : : :: : **: : . .:: .* : . . : * : .: : :: *: * . :* .*:. :* ", "identical_positions": 210, "similar_positions": 324, "identity": "12.7%" }, { "cls_id": "homologset.agr.RGD:621054", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7M6Y3-1", "uniprot_id": "PICAL_MOUSE", "id": "Q7M6Y3-1", "name": "Phosphatidylinositol-binding clathrin assembly protein", "aln": "--MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGN-ERFIQYLASRNTLFNLSNFLDK-----------SGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRG-ADGVMR--------TMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQ----APSSLLDALEQHLASLEGKK---IKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALK-EQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSS-SNSTSKLPNDLLDLQQPTFHPSVHAMSAAPQGASTWGDPFSATLDAVEDAIPSLNPFLTKSSGD-VHLPIAS-DVSTFTTRTPTHEMF----------------------------------------------------------VGFSPSPVAQPHSSAGLNVDFESVFGNKSTN-VAVDSGGFDELGGLLKPTVASQNQSLPVAKLPPNKLVSDDLDSSLANLVGNLGIGNGTTKNDVSWSQPGEKKLTGGSNWQPKVAPTTAWSAATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O55012-1", "uniprot_id": "PICAL_RAT", "id": "O55012-1", "name": "Phosphatidylinositol-binding clathrin assembly protein", "aln": "--MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGN-ERFIQYLASRNTLFNLSNFLDK-----------SGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRG-ADGVMR--------TMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQ----APSSLLDALEQHLASLEGKK---IKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALK-EQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSS-SNSTSKLPNDLLDLQQPTFHPSVHAMSAAPQVASTWG-------DAVDDAIPSLNPFLTKSSGD-VHLPISS-DVSTFTTRTPTHEMF----------------------------------------------------------VGFSPSPVTQPHPSAGLNVDFESVFGNKSTN-VAVDSG-----GGLLKPTVASQNQSLPVAKLPPNKLVSDDLDSSLANLVGNLGIGNGTTKNDVSCSQPGEKKLTGGSNWQPKVAPTTAWSAATM--------APPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVPGAQIQFM--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13492-1", "uniprot_id": "PICAL_HUMAN", "id": "Q13492-1", "name": "Phosphatidylinositol-binding clathrin assembly protein", "aln": "--MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGN-ERFIQYLASRNTLFNLSNFLDK-----------SGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRG-ADGVMR--------TMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQ----APSSLLDALEQHLASLEGKK---IKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALK-EQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSS-SNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGD-VHLSISS-DVSTFTTRTPTHEMF----------------------------------------------------------VGFTPSPVAQPHPSAGLNVDFESVFGNKSTN-VIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATM--------APPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GJ72-1", "uniprot_id": "A0AC58GJ72_DANRE", "id": "A0AC58GJ72-1", "name": "Phosphatidylinositol-binding clathrin assembly protein", "aln": "--MSGQSITDRITAAQHIVTGSAVSKTVCKATTHEVMGPKKKHLDYLIQCTNEMNVNIPQLADTLFERTTNTSWVVVFKSLITTHHLMVYGN-ERFVQYLASRNTLFNLSNFLDK-----------SGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRG-ADGVMR--------TMNTEKLLKTIPIIQNQMDALLDFNVNANELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKAQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQ----APSSLLDALEQHLASLEGKK---VKDSTAASRASTLSNAVSSLANTGISFTKADEREKQAALEEEQARLKALK-EQRLKELSKKPSTTSTTAASPVSTETGSISTVPAIDLFSATSTFANSTPKVPNDLLDLQ-PAFQPSLP-LSSGLPLANTWGDPFTST-EAADDSIPNLNPFLTKPVVDPVHLPVVSSDAVSFSSRTPSHEMFGDSF-------------------------------CSPTAYPNTPLFHSEPSTVAGLFGGFSAPPAAQPPSSTGLNVDFDSVFGNKSVA-NSTDSAD-DILGGILKPTVTSPNQGLTPSAQLSGKLVSDDLDSSLANLVGNLGIGNGTAKNDIHWSQPGEKKLTGGMNWQPKTAPTTTWNPATMNGMLFPQYAPSVMAFPATTPTGMMGYAMPPQMGSMAMMTQPTMMYTQPVMRPANPFGPVSGAQLSTASSPSSSSPLRAPGQDPFAQLSMKDFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z9M1-1", "uniprot_id": "A0A8M6Z9M1_DANRE", "id": "A0A8M6Z9M1-1", "name": "Phosphatidylinositol-binding clathrin assembly protein", "aln": "--MSGQSITDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIHCTNEMNVNIPQLADSLFERTTNTSWVVVFKSLITTHHLMVYGN-ERFIQYLASRNTLFNLSNFLDK-----------SGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRG-VDGVMR--------TMNTEKLLKTIPIIQNQMDALLDFNVNANELTNGVINAAFMLLFKDSIRLFAAYNEGIINLLEKYFDMKKVQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQFTVCAPSSLLDALEQHLASLEGKK---VKDSTAASRASTLSNAVSSLANTGMSFTKVDEREKQAALEEEQARLKALKQEQRLKELSKRP-SFATTDTSPVSTTAACISTAPAIDLFSTPSC-SNGALKMESDLFDLQ-TNFQSSMQ---PGPSVATAWGDPFSSS-EAVDDSIPNLNPFLSKLVVDGAHLPVMSSDGVSFSSRTSGHEIFSDQYNPFIDSSSSVSTNYKRTVRIEHLISDSFGQPSMVQHLPNPSPFQSEPSTVAGLFRGYGAPQMPPPQNSGELRVDFESVFGTKAASSNSLDTD-----AGILKPTVAGSSQ---SSNQLPEKLVSDDLDSSLANLVGNLGIGNGTTKNDIHWSQPGEKKLTGGMNWQPKTAPSTTWNPVSMP--------PSIMAFPATTPTGMMGYGMPPQLPSMSMMTQPTMMYTQPVMRPSNPFGSVSSAQPSAASSPSSQSPLRAPGQDPFAQLSLKDFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VI75-1", "uniprot_id": "PICAL_DROME", "id": "Q9VI75-1", "name": "Phosphatidylinositol-binding clathrin assembly protein LAP", "aln": "MTMAGQTINDRLLAARHSLAGQGLAKSVCKATTEECIGPKKKHLDYLVHCTNEPNVSIPHLANLLIERSQNANWVVVYKSLITTHHLMAYGN-ERFMQYLASSNSTFNLSSFLDKGTVQDGGMGVPGGRMGYDMSPFIRRYAKYLNEKSLSYRAMAFDFCKVKRGKEEGSLR--------SMNAEKLLKTLPVLQAQLDALLEFDCQSNDLSNGVINMSFMLLFRDLIRLFACYNDGIINLLEKYFDMNKKHARDALDLYKKFLVRMDRVGEFLKVAENVGIDKGDIPDLTK----APSSLLDALEQHLATLEGRK---VSAANTPTQSSSSAFGTAAASSKFDTTNGIDEQLKAQVLAEEEAAMNQYK----------------SKVSSPTSSGAAGASAALTNPFLS-----------------------------------------------------------------------------------------------------------------------------------------------------------SPPAAQAGQP------IVDLFGAASAQ-----------------PAAAAAATKASDDLLQLGNPFADMFDASGGGAAAVGATGN---------AGDGTAKYDGGAGSSP-------------------------FDWGATDDDGGAAQ-------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53309-1", "uniprot_id": "AP18B_YEAST", "id": "P53309-1", "name": "Clathrin coat assembly protein AP180B", "aln": "-------------------MSSLYTKLVKGATKIKMAPPKQKYVDPILSGTSS-ARGLQEITHALDIRLSDTAWTIVYKALIVLHLMIQQGEKDVTLRHYSHNLDVFQLRKISHT-----------TKWSSNDMRALQR-YDEYLKTRCEEYGRLGMDHLRDNYSSLKLGS-------KNQLSMDEELDHVESLEIQINALIRNKYSVSDLENHLLLYAFQLLVQDLLGLYNALNEGVITLLESFFELSIEHAKRTLDLYKDFVDMTEYVVRYLKIGKAVGLKIPVIKHITT-------KLINSLEEHLREETKRQRGEPSEPQQDRKPSTAISSTSSHNNNSNDKNKSIAQKKLEQIREQKRLLEQQLQNQQLLISPTVP----QDAYNPFGSQQQDLNNDTFSFEPTQPQMTAQVPQPTANPFLIPQQQQQALQLTSASTMPQ------PSEIQITPNLN--------NQQTGMYASNLQYTPNFTGSGFGGYTTTENNA-----------------------------------------------------------IMTG-TLDPTKTGSNNPFSLENIAREQQ------------------QQNFQNSPNPFTLQQAQTT-PILAHSQTGNPFQAQNVVTSPMGTYMTNPVAGQ----------------------LQYAS------------TGAQQQPQMMQGQ-QTGYVMVPTA------------------FVPINQQQQQQQHQQE---------NPNLIDI------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38856-1", "uniprot_id": "AP18A_YEAST", "id": "P38856-1", "name": "Clathrin coat assembly protein AP180A", "aln": "--------------------MTTYFKLVKGATKIKSAPPKQKYLDPILLGTSN-EEDFYEIVKGLDSRINDTAWTIVYKSLLVVHLMIREGSKDVALRYYSRNLEFFDIENIRGS-----------NGSASGDMRALDR-YDNYLKVRCREFGKIKKDYVRDGYRTLKLNSGNYGSSRNKQHSINIALDHVESLEVQIQALIKNKYTQYDLSNELIIFGFKLLIQDLLALYNALNEGIITLLESFFELSHHNAERTLDLYKTFVDLTEHVVRYLKSGKTAGLKIPVIKHITT-------KLVRSLEEHLIED-------------DKTHNTFVPVDSSQGSAGAVVAKSTAQERLEQIREQKRILEAQLKNEQVAISPALTTVTAAQSYNPFGTDS--------SMHTNIPMAVANQTQQIANNPFVSQTQPQVMNTPTAHTEPANLNVPEYAAVQHTVNFNPVQDAGVSAQQTGYYSINNHLTPTFTGAGFGGYSVSQDTT-----------------------------------------------------------AASNQQVSHSQTGSNNPFALHNAATIATGNPAHENVLN----NPFSRPNFDEQNTNMPLQQQIISNPFQNQTYNQQQFQQQKMPLSSINSVMTTPTSMQGSMNIPQRFDKMEFQAHYTQNHLQQQQ------------QQQQQQQQQQQQQPQQGYYVPATAGANPVTNITGTVQPQNFPFYPQQQPQPEQSQTQQPVLGNQYANNLNLIDM------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * **. : **:*::* :: *.. .: .:.. * * :: *.:*:*:*:. * :: *. : ::: : *:: .: . . ** .: * * .**: :. .: : *. : . . : *. : :: *::**: . :* * :: .* **.:* : *: . *:*:*.***.:*::. :.. **:** *: : .:** .: .*:. * .:: .*: :**:** .: :: . : : : *:: :: .* .: . . : . . . : ", "identical_positions": 59, "similar_positions": 118, "identity": "7.57%" }, { "cls_id": "homologset.agr.RGD:621055", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55171-1", "uniprot_id": "ACOT2_RAT", "id": "O55171-1", "name": "Acyl-coenzyme A thioesterase 2, mitochondrial", "aln": "-------------------MVASSFAVLRASRLCQWGWKSWTQLSGPPPLSTGGRTT--FARTNATLSLEPGSRSCWDEPLSITVRGLAPEQPVTLRAALRDEKGALFRAHARYRADAGGELDLARAPALGGSFTGLEPMGLIWAMEPERPLWRLVKRDVQKPYVVELEVLDGHEPDGGQRLAQAVHERHFMAPGVRRVPVRDGRVRATLFLPPEPGPFPEIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKTMETMRIEYFEEAVNYLRGHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTVCYKDETIPPVSLLRDKVKMTKDGLLDVVEALQSPL--VDKKSFIPVERSDTTFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIICYPEAGHYIEPPYFPLCSAGMHLLVGANITFGGEPKPHSVAQLDAWQQLQTFFHKQLSGKS-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYR9-1", "uniprot_id": "ACOT2_MOUSE", "id": "Q9QYR9-1", "name": "Acyl-coenzyme A thioesterase 2, mitochondrial", "aln": "-------------------MVASSFAVLRASRLCQQDWKSWARLFVPPPLSTGGRTT--WARTNATLSVEPEGRSCWDEPLSIAVRGLAPEQPVTLRSALRDEKGALFRAHARYRADAGGELNLARAPALGGSFSGLEPMGLLWAMEPERPLWRLIKRDVQTPFLVELEVLDGHEPDGGQRLAQAVHERHFLAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKSIETMHMEYFEEAVNYLRSHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTISYKDETIPPVSLLRNQVKMTKDGLLDVVEALQSPL--VDKKSFIPVERSDTTFLFLVGQDDHNWKSEFYADEISKRLQAHGKEKPQIICYPAAGHYIEPPYFPLCSAGMHLLVGANITFGGEPRAHAVAQVDAWQQLQTFFHKQLGSKS-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49753-1", "uniprot_id": "ACOT2_HUMAN", "id": "P49753-1", "name": "Acyl-coenzyme A thioesterase 2, mitochondrial", "aln": "MSNKLLSPHPHSVVLRSEFKMASSPAVLRASRLYQWSLKSSAQFLGSPQLRQVGQIIRVPARMAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLLCQTRHERYFLPPGVRREPVRVGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAMNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLHYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T759-1", "uniprot_id": "A0A8N7T759_DANRE", "id": "A0A8N7T759-1", "name": "", "aln": "-----------------------MYATLKCA-LKPFARNTLAKMHYS---------------SGVSIRLLPSYKCSFEDPVHVTVSGLNPHQRVDLRSKITDEGGRDFKALATYQADDSGQIDLKRDSSLGGSFTGVEPMGLYWALKADTISCKFKLKDVTRPALVDIEVVSDD-----KVLAKVTNERHCLTDGVRRRPLNEDRIRGTLFMPPGKGPFPGILDTYILRGGHFELRAALLAKRGFAVLALAYQNYQDLPKSSDKFHLEYFEEGIDFLRQQPEVKGQKIGLLSISKSGDLALSMSTFLPDIAATVWINGCNANSVVPLYYKDMYIPPLTLDFKKKKITPLGLVDMLDVVKDPMSKEGLPSVIPIERAPGRFMFIASEANMNWRSAYHAKLACDRLKAHGKKNYELVKYEKAGHFIEVPYMPFCFANFHSVLKQPVLFGGEPKCHSEAQVDAWPRIINFFKKHLATADYNLSPMLEENIHEMSQQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1NZE7-1", "uniprot_id": "A0A8M1NZE7_DANRE", "id": "A0A8M1NZE7-1", "name": "", "aln": "-----------------------MYAALKFA-FMPFAR-SLAKVHYS---------------SGVSIKLLPSYKCSFEDPVHVMVSGLNPHQRVNLRSKITDEGGRDFKASAIYLADDNGQIDLKRDSSAGGSFSGVEPMGLFWALKADLLSCKFKLKDVTRPALVDIEVVGEDE----KVLAKVTNERHCLSEGVRRSLVTEGRIRGTLFMPTGNGPFPGILDTYILKGGPFELRAALLAKRGFAVLALAYQNYQDLPKKADKFHLEYFEEGLDFLRRQPEVKGQKIGLLSISKSGDLALSMSTFLPDITAAVWINGCNANSLIPLYYKDMYIPPLTLDFKKKKMTALGLVDMLEVVNDPMSKEGLPTVIPIERASASFMFIASEADMNWRSVYHAKLACDRLKAHGKNNYELVKYEKAGHFIEVPYMPFCLAAFHGVLEQPVLFGGEPKAHSEAQVDAWQRIIIFFKRTLGS-------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*: : : : ::. . .:: : * :..:::*: : * ** *.* * **: : ** * *:* * * ** *:::* * .: ****:*:***** **::.: :: :** * *::**:. . : *.:. :**: :. **** : .*:*.***:*. **** *:* : ** :* **:*** :****:**** **:****. :.:::*****.:::* :***** :***.***.*:* *:*::** .*:*:* ***. * .: **. :**: : .: *:* * *:::.::.*: . :.**:**: *:*:..: : **:* ::* ..**:***:.: ::: * :**:** **:*:* * :* :: : :****: *: **:*** :: **:: *. ", "identical_positions": 161, "similar_positions": 144, "identity": "32.66%" }, { "cls_id": "homologset.agr.RGD:621056", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62764-1", "uniprot_id": "YBOX3_RAT", "id": "Q62764-1", "name": "Y-box-binding protein 3", "aln": "MSEAGEATTGG-TTLPQAAADAPAAAPPDPAPKSPAASGAPQ--APAPAALLAGSPGGDAAPGPAPASSAP-----AGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFEPPAADGQFSGARNQLRRPQYRPPYR-QRRFPPYHVGQTFDRRS-RVFPHPNRMQAGEIGEMKDGVPEGAQLQ--VHRNPTYRPRFR-RGPARPRPAPAIGEAEDKENQQAANGPNQPSARRGFRRPYNYRRRPRPLNAVSQDGKETKAGEAPTEN-PAPATEQSSAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKB3-1", "uniprot_id": "YBOX3_MOUSE", "id": "Q9JKB3-1", "name": "Y-box-binding protein 3", "aln": "MSEAGEATTGG-TTLPQAAADAPAAAPPDPAPKSPAASGAPQ--APAPAALLAGSPGGDAAPGPAPASSAP-----AGGEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFEPPAADGQFSGARNQLRRPQYRPPYR-QRRFPPYHVGQTFDRRS-RVFPHPNRMQAGEIGEMKDGVPEGTQLQ--AHRNPTYRPRFR-RGPARPRPAPAIGEAEDKENQQAANGPNQPSARRGFRRPYNYRRRSRPLNAVSQDGKETKAGEAPTEN-PAPATEQSSAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16989-1", "uniprot_id": "YBOX3_HUMAN", "id": "P16989-1", "name": "Y-box-binding protein 3", "aln": "MSEAGEATTTTTTTLPQAPTEAAAAAPQDPAPKSPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFDPPATDRQFSGARNQLRRPQYRPQYR-QRRFPPYHVGQTFDRRS-RVLPHPNRIQAGEIGEMKDGVPEGAQLQGPVHRNPTYRPRYRSRGPPRPRPAPAVGEAEDKENQQATSGPNQPSVRRGYRRPYNYRRRPRPPNAPSQDGKEAKAGEAPTEN-PAPPTQQSSAE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B5DE31-1", "uniprot_id": "YBOX1_DANRE", "id": "B5DE31-1", "name": "Y-box-binding protein 1", "aln": "-----------------MSSEAETQQPPQPAADAESPS------SPAAAATAG-----------------------------DKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNRYRR--YPRRRAPPRDYQENYQSD----PEAEPREKREGAESAPEGEMQQQQRRPTYPGRRRYPPYFVRRRYGRRPPYTNSQRGEMTEGGEGEENQGGPDQGNKP---MRQNYYRGFRPSRGPSRPR--PVRDGEEDKENQ-SESGQNQEPRQRRYRRNFNYRRR-RPQTTKPQDGKDSKAADASADKSAAPEAEQGGAD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::* : * :**..: * :**.** . :***:*************************************************************************.****:**:*****.**** * ***.***:* : :.: .*. : *....:::: * ** * :**:***.* : :.**. . .: ..: * ** ::* *: : *: ** ***.*** *. . ****** : .* ** . :* :** :***** ** .: .****::**.:*.::: .** ::*..*:", "identical_positions": 167, "similar_positions": 78, "identity": "44.53%" }, { "cls_id": "homologset.agr.RGD:621057", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1L0-1", "uniprot_id": "A0A0G2K1L0_RAT", "id": "A0A0G2K1L0-1", "name": "Tenascin", "aln": "MGAVTWLLPGIFLALFALTPEGGVLKKVIRHKRESGL-----NLTLPEENQPVVFNHIYNIKLPMGSQCSVDLESTSGEKDLSPTPESSGSFQEHTVDGENQIVFTHRINIPRRACGCA-AAPDVKELLSRLEELEMLVSSLREQCTMGTGCCLQPAEGRLDSRPFCSGRGNFSAEGCGCVCEPGWKGPNCSEPECPGNCNLRGQCLDGQCICDQGFTGEDCSQLACPNDCNDQGKCVNGVCVCFEGYAGLDCGLEVCPVPCSEEHGMCVDGRCVCKDGFAGEDCNEPLCFNNCNNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGELTCPNNCQGHGQCEEGQCVCNEGFAGADCSEKRCPADCHHHGRCLNGQCECDDGFTGADCGELQCPNGCSGHGRCVNGQCVCDEGYTGEDCSQRRCPNDCHNRG-------------------------------HCVQGKCICEQGFKGFDCSEMSCPNDCHQHGRCVNGMCICDDDYTGEDCRDRRCPRDCSQRGRCVDGQCICEDGFTGSDCAELSCPGDCHGHGRCVNGQCICHEGFTGKDCKEQRCPSDCHGQGRCEDGQCICHEGFTGLDCGQRSCPN-------------------------------DCSNQGQCVAGRCICNEGYTGVDCSEVSPPKDLIVTEVTEETVNLAWDNEMRVTEYLIMYTPTHADGLEMQFRVPGDQTSTTIRELEPGVEYFIHVFAILENKRSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKKVTTTRLDAPSQIEVRDITDTTALITWSKPLAEIDSIELSYGIKDVPGDRTTIDLTHEDNQYSIGNLKPDTEYEVSLISRRVDMASNPAKETFITGLDAPRNLRRVSQTDNSITLEWRNVKADIDSYRIKYAPISGGDHAEIDVPKSQQATTKTTLTGLRPGTEYGVGVSAVKGDKEGDPATINAATEIDAPRDLQVSETTQDSLTLFWKTPLAKFDRYRLNYSLPTGQSIEIQLPKDATSHVLTDLEPGQEYTVLLTAEKGRHKSKPARVKASTEEVP----------------------------------------------------------------------------------------------------------------------------------------------------------------------SLENLTVTEAGWDGLRLNWTADDLAYEYFVIQVQEANKVETAHNFTVLGNLRTADIPGLKAATPYRVSIYGVARGYKTPVLSAETFTGKT-PSLGEVTVAEVGWDALKLNWTAPEG-AYTNFFIQVLEADMTQTVQNLTVPGGLRSVDLPGLKAATRYYITVRGVTQDFSTAPLSVEVLTEEIPQLGGLSVTEVSWDSLTLNWTTDD-------------------------------------------------------------------------------------------LAYKHFIIQVQEANNVEAAQNLTVSGSLRVVDIPGLKADTPYRVSIYGVIQGYRTPMLSADVSTAKEPEIGNLNISDVTPESFNLSWTATDGIFDMFTIEIIDSNRLLQTAEHNISGAERTAHISGLPPSTDFIVYLSGIAPSIRTKTISTTATTEALPLLENLTISDTNPYGFTVSWTASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVLVSGFT-QGHQTKPLRAETITEAEPEVDNLLVSDATPDGFRLSWTADEGIFDSFVIRIRDTKKQSEPQEITLPSPDRTRDITGLREATEYEIELYGISRGRRSQPVSAIATTAMGSPKEIMFSDITENAATVSWRAPTAQVESFRITYVPVTGGPPSMVTVDGTDTETRLVRLTPGVEYHVSVIAMKGFEESDPVSGSLITALDGPSGLLTANITDSEALAMWQPAIATVDSYVISYTGERVPEITRTVSGNTVEFELHDLEPATEYTLSVFAEKGHQKSSTIATKFTTDLDSPRELTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTARIQALSGSLRSKLIQTIFTTIGLLYPFPRDCSQAMLNGDTTSGLYTIYINGDKTQALEVYCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDRREEFWLGLDNLSKITAQGQYELRVDLQDHGESAYAVYDRFSVGDAKSRYKLKVEGYSGTAGDSMNYHNGRSFSTYDKDTDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSNFRNLEGRRKRA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YX1-1", "uniprot_id": "TENA_MOUSE", "id": "Q80YX1-1", "name": "Tenascin", "aln": "MGAVTWLLPGIFLALFALTPEGGVLKKIIRHKRESGL-----NMTLPEENQPVVFNHIYNIKLPMGSQCSVDLESASGEKDLTPTPESSGSFQEHTVDGENQIVFTHRINIPRRACGCA-AAPDVKELLSRLEELELLVSSLREQCTMGTGCCLQPAEGRLDTRPFCSGRGNFSAEGCGCVCEPGWKGPNCSEPDCPGNCNLRGQCLDGQCICDEGFTGEDCSQLACPNDCNDQGRCVNGVCVCFEGYAGPDCGLEVCPVPCSEEHGMCVDGRCVCKDGFAGEDCNEPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGELTCPNDCQGRGQCEEGQCVCNEGFAGADCSEKRCPADCHHRGRCLNGQCECDDGFTGADCGDLQCPNGCSGHGRCVNGQCVCDEGYTGEDCSQRRCPNDCHNRG-------------------------------LCVQGKCICEQGFKGFDCSEMSCPNDCHQHGRCVNGMCICDDDYTGEDCRDRRCPRDCSQRGRCVDGQCICEDGFTGPDCAELSCPSDCHGHGRCVNGQCICHEGFTGKDCKEQRCPSDCHGQGRCEDGQCICHEGFTGLDCGQRSCPN-------------------------------DCSNQGQCVSGRCICNEGYTGIDCSEVSPPKDLIVTEVTEETVNLAWDNEMRVTEYLIMYTPTHADGLEMQFRVPGDQTSTTIRELEPGVEYFIRVFAILENKRSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKKVTTTRLDAPSHIEVKDVTDTTALITWFKPLAEIDSIELSYGIKDVPGDRTTIDLTHEDNQYSIGNLRPDTEYEVSLISRRVDMASNPAKETFITGLDAPRNLRRVSQTDNSITLEWRNVKADIDSYRIKYAPISGGDHAEIDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKGDKESDPATINAATEIDAPKDLRVSETTQDSLTFFWTTPLAKFDRYRLNYSLPTGQSMEVQLPKDATSHVLTDLEPGQEYTVLLIAEKGRHKSKPARVKASTEEVP----------------------------------------------------------------------------------------------------------------------------------------------------------------------SLENLTVTEAGWDGLRLNWTADDLAYEYFVIQVQEANNVETAHNFTVPGNLRAADIPGLKVATSYRVSIYGVARGYRTPVLSAETSTGTT-PNLGEVTVAEVGWDALTLNWTAPEG-AYKNFFIQVLEADTTQTVQNLTVPGGLRSVDLPGLKAATRYYITLRGVTQDFGTAPLSVEVLTEDLPQLGGLSVTEVSWDGLTLNWTTDD-------------------------------------------------------------------------------------------LAYKHFVVQVQEANNVEAAQNLTVPGSLRAVDIPGLKADTPYRVSIYGVIQGYRTPMLSTDVSTAREPEIGNLNVSDVTPKSFNLSWTATDGIFDMFTIEIIDSNRLLQTAEHNISGAERTAHISGLPPSTDFIVYLSGIAPSIRTKTISTTATTEALPLLENLTISDTNPYGFTVSWTASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVLVSGFT-QGHQTKPLRAETITEAEPEVDNLLVSDATPDGFRLSWTADEGIFDSFVIRIRDTKKQSEPQEISLPSPERTRDITGLREATEYEIELYGISRGRRSQPVSAIATTAMGSPKEIMFSDITENAATVSWRAPTAQVESFRITYVPMTGGAPSMVTVDGTDTETRLVKLTPGVEYRVSVIAMKGFEESDPVSGTLITALDGPSGLLIANITDSEALAMWQPAIATVDSYVISYTGERVPEVTRTVSGNTVEYELHDLEPATEYILSIFAEKGQQKSSTIATKFTTDLDSPREFTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYSARIQALSGSLRSKLIQTIFTTIGLLYPFPRDCSQAMLNGDTTSGLYTIYINGDKTQALEVYCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDRREEFWLGLDNLSKITAQGQYELRVDLQDHGESAYAVYDRFSVGDAKSRYKLKVEGYSGTAGDSMNYHNGRSFSTYDKDTDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSNFRNLEGRRKRA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24821-1", "uniprot_id": "TENA_HUMAN", "id": "P24821-1", "name": "Tenascin", "aln": "MGAMTQLLAGVFLAFLALATEGGVLKKVIRHKRQSGV-----NATLPEENQPVVFNHVYNIKLPVGSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRINIPRRACGCA-AAPDVKELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRG-------------------------------RCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPS-------------------------------DCNNLGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAP----------------------------------------------------------------------------------------------------------------------------------------------------------------------ELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGET-PNLGEVVVAEVGWDALKLNWTAPEG-AYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT-QGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QYE2-1", "uniprot_id": "F1QYE2_DANRE", "id": "F1QYE2-1", "name": "", "aln": "MGMRGLLLASMAVAVLVHLSSAGLVKRVIRHRRESLS-PTTENLTLPSPDQPVVFNHVYNINVPSGSLCSVDMDSPGT-TEIKPKSEQSDQHIEHTTDGENQIVFTHRINIPKQACGCDNHMPDMKELLNRLEMLEAEVSSLREQCTSGAGCCSAQVTGEVTTKPYCSGRGNYSTDTCSCVCEPGWKGVNCSEPECPNYCQDQGRCEDGKCVCFEGFGGEDCGIELCPVDCGENGECIDGACICAEGFIGEDCSLSNCPSNCLGR-GRCVDDECVCDEPWTGFDCSELICPNDCFDRGRCENGTCYCDEGFTGEDCGELTCPQNCNHHGRCVNGQCICNIGYSGEDCSKLTCLNDCSERGHCFNGKCICDPGFEGEDCSLLSCPDNCNGRGHCVNGECICGPGYEGDDCSELSCLNNCHDRGRCVNGKCICKAGFAGEDCSIKTCPHDCHGRGECVDGKCVCHDGFAGEHCGIKTCPHHCHGHGQCVDGKCICHKGFAGEDCSIKTCPNHCHGQGQCIDGKCICHDGFAGEDCSIKTCPNHCHGRGRCVDGKCICHDGFAGEDCNIKTCPNDCHDHGECVDGKCICHAGFTGHDCSELTCPNDCHNRGRCVNGQCVCNIGFTGEDCGTKTCPNNCLDRGFCEDGKCVCFEGYTGEDCSVLTCPADCNDQGQCLNGMCICDLGFTGDDCSEISPPRDLTVTEVDPETVDVAWVNEMLVTEYLITYVPTAPGGLEMEMRVSGEKKTATIRELEPGIEYLISVFAVLNSKMSVPVSARIATHLPEPEGLKFKSVKETSVEVEWDPLNIPFDGWNLIFRNT-KEEDGEILNSLAPPETTFEQSGLGPGQEYEVKLEVVKNNTRGPPASKNVVTMIDAPSQVDVRDVTDTTALVTWLQPVAQVDGISVSYGPNTDSSDRNTIELSSIETQYHLAELSPDTEYEVSLMARRGEMSSFPIYETFTTDLDSPKHLKAIEQTDESITLEWRNSRANVLNYRVKYGPLSGGEHGELVFPSGLQDTTQAKITGLRPGTEYGMGVTSIKEERESLPATTNAVTDLDPPKDLQVSETTETTLALVWRRPVAKIDTYSLVFIPADGDKTELKIPGAANTYILTGLNPGMLHTITLTAERGRKMSAPATLSAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDEEKPQVGNITISDVSWDSFSMSWDLDRG-EVEGFLIEVSDPDGLSDGQNHTLSGQEFSLAVTDLSPSTFYRVTLYGLYKG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELLDP---------------------------------------VFAEAITEAEPEVEHITVSDITPHSFKVTWTAPEAVFDSFALKVLDSSGLGRPHQISVSGDKRTEAVTGLNEDTDYEIELFGIILGRKFQPIFTVARTGLGTPKGIRFSDVTDTSATVHWTMPHTRVDNYRVIYVPIQGGSPLTLRVDGGESQAMLSNLTPGVTYQVTVIAVKGLEESEPGSERVTTALDKPRGLTAVNISDTEALLLWQPSIATVDGYVITYSADSVAPVMERVSGNTVEFEMSSLTPATLYTVKVYAFRDTAKSAATSTDFTTDVDAPQNLAASNIQTETAMLTWKPPRADISGYILSFESADGVVKEVVLSPTATFYSMSQLTASTEYTVKLQAIAGPKRSRVISTVFLTIGVLYKHPKDCSQALLNGDTTSGLYTIYLRGDESQPLQVYCDMTTDGGGWIVFVRRQSGKVEFFRNWKNYTAGFGDLNDEFWLGLSNLHKITSFGQYELRVDLRDKGESAYAQYDKFSISEPRARYKVHVGGYSGTAGDSMTYHHGRPFSTYDNDNDIAVTNCALSYKGAFWYKNCHRVNIMGRYGDNSHSKGVNWFHWKGHEHSVEFAEMKIRPANFRNFEGRKKRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TRK9-1", "uniprot_id": "A0AB32TRK9_DANRE", "id": "A0AB32TRK9-1", "name": "", "aln": "MSSRGLTLSCLLLITLMALNHAGLVKKLIRQRREALNVPGIHNVTLSNSSRPVIFNHVYNIKVPGSPLCSVDLDAPEG-SDVELRDAPS----EHSVDGSNQIVFTHRINIPKQACGCTDGLPDLKDLLSRLEMLEGEVSTLREQCGAESTCCSAQVTGAIGTKPFCSGHGNYSTETCGCVCAPGWKGLNCTIPDCPGDCSDQGRCVNGKCECFEGFTGDDCSTDACLIDCGDNGRCLNGKCVCSEGFSGEYCTESDCLNNCLGR-GRCVDGECVCDEPWTGFDCSELICPNDCYDRGRCENGTCYCDRGFTGEDCGALACPNDCSGRGFCIDGRCVCDAGYTGEDCSSLTCPNNCNDRGRCSNGVCICEVGFHGEDCGRISCPSNCNNRGHCVDGRCECDVGFQGHDCSELSCPNNCNNRGRCVNGQCVCDEGFGSEDCGLKTCPSDCYGRG-------------------------------QCVDGECVCFANFAGEDCSELRCPNSCQNRGRCIAGQCVCDEGFTGEDCSQRKCPNDCLGRGRCVDGRCVCQDGFKGQDCSVPTCPGNCNDHGRCVNGKCVCDEGFFGDACSDRSCLN--------------------------------------------------------------DCSDVGQCVDGRCICDEGYIGEDCSDVSPPEDLTVTDVSTQKVNLTWRNEMLVTEYLITYVPTAPGGLQMDFRVAGDRTSATVSELEPGIEYLINVYAVLNNKRSIPVSARVATYLPQPEGLRFTSITDSTVEVVWEQLNFPFDGWELIFRNT-KEENGKIVNNLTPSQTTFEQQGLGPGQEYEVTLSVIKNNTRGPETSSTVVTRIDSPAQIEVADVTDRSAVISWSKPLAPVDGFKVSYGPSTDPLIHRDVELSASETQYSLEDLKPDTQYRVALSSQRGDVTSEPIIESFTTGLDAPSELRAVDQTDSSITLEWKNSRSSIDGYRIKYGPIAGGAHGEDMFPKKAGDTTWATITGLKPGTEYGIGVTAVQNERESEPATTNALTDLDPPRDLEVQSSTETSVDLVWKRPRAKISTYRLAYVSVEGRREEIELPASASTSTLSGLMPGMSYTVTLVAERGHRRSAPATVTASTASFTFYLANAFPEFGSAKGADDNIISFVSLENSETPFSGSGLEDPIGGSFTISNVSSHGFDLMWDSNKLSGFDSFTVEVTDFSGMWKEEVHLNGKVNDTKIRGLKSSTEYQVRLYGLSNNQRSSLLEAVAVTAPKSTSPDVVALTVKRVSAAQPSVSTSTLLTEDFKAEEPLSDLKVTEVGANSLRLSWQAPERAFSSFIIELNSTSNTSKDSIIKVSGEARHAHVEGLNADMNYEITLYGRKAGEKSQPISVFVKTEEQKPQIGSLSLSDVSWDSFNVSWIIEDGPAFDSFVIEVANSAGP-ERQNLSVSGDARDLWMSGLSPGTSYMITLYGVHQGSILGSINVEAATDRAPAMGNLYVSNVTSQSFFVSWNDTKGEIERFVLEIIDSSWQQEPIEYNLSQSVQSYEITGLRPTTDYIAYVTGVMKGRRTDSVSAVASTAAEPDLSGLVVSNVTSDSVSLSWRTGEKAFDNFIVEVRESALPSQASGRTFGAGVRSAVLNGLRGNTTYQIKLYATVAGANTDALTTVVTTEPKPELGRVVVSERLANSLTLSWSTLSGHFDGFAARVSDREQLYDVVELRLSGTERNTSVQGLVDSTVYDIMFYGVSHGRQTPSVYFNTSTASLPKVENLTVWDVTPYGFRVSWDA-DSGFSHFQVKVSDSGQLLEPQELVVPGNEASLEVLGLITGIGYEVSVTGVSGTGLRSRPITTVAVTEAEPEIEHLFVSDVTPESFRLSWTTEDDVFDRFVLKVRDSRKLSHPREFSMSGDERTKVLTQLLGGTEYEIELYGVTLERRSQPVTAVVKTGLGALRDLHFSDITDTSAVVYWTLPRAQPDSYRITLIPIQGGSPMIVQVDGSQSQVSLRNLIPGETYQVSVIAVKGLEESEPVSDTFTTALDTPRSLTVVNVTDSSALLFWQPAVATVDGYMITYSADTVPPISEQVSGNTVEFEMNSLAPATQYTVSVYAIRDREKSLPATADFTTDVDAPRDLVASNIQTDSAVLSWTPPRAAITGYTLTFQNSDADVREVIVDPSVASHTLSNLRSTTKYTVILQAVSEDKRSRSISTEFTTVGMLYGHPRDCSEALLNGETSSGPYTIYINGDEKQPLRVYCDMTTDGGGWMLFLRRQSGKLNFYRNWRNYSAGFGDTSDEFWLGLSNLHKITAAKQYEIRVDLRDGSETVFAVYDRFYIGDPRSRYKIQIGAYSGTAGDSLTYHQNRPFSTYDSDNDIAITNCALSYKGAFWYKNCHRVNLMGKYGDSSHSKGINWFHWKGHEHSIPFAEMKIRPANFRNLEGRRKRS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *. : : : .*::*::**::*:: * **.. .:**:***:***::* .. ****:::. .:: * **:.**.************::**** **:*:**.*** ** **:***** : ** . * : ::*:***:**:*:: *.*** ***** **: *:**. * :*:* :*:* * :** *:**. * **.::*.*::* *:* **: * * . * * . * ***. ***.: ::* **.: :* *:* :**** :. * **.*******. * **::* :* *::* * *: *::****.. ** : * :*:* :* *:*: ** * **. ** :*: :*:*::*.* *. *: * **.:*.* *.* .:******:*:*. *: .***. ** **:.** **:*:*:* .* * *** *** *: :*:*: * *:*.:.::**** : **..* ** ****:*:*.*** * ** :**.:*:.:*.**:*:*:*. ** *. *.: * . **.: ***: * ***: *: * ***::***.** **:* :.*:::* *** *****: *.** .**:*::**.*::.:: : *****:**:* *:*:*:.* *:*****:**:** ****:*.*:.:::*** *: *::.*: *::**** **::*:* :.* .:*::.* **.******:.* ::******* . ..* :*:*::::* *:** :*:::* :*:* :*.:.::** . . : ::*: :.** : :* ***:*.*:* ::* :::* * *:* *.**:* .*: :.***.******:* :: : .**:**.*::** *.* .*. ** :.:***:******:**:::: ::*. *** ** *::*.*:**.*..::: :: :.* * **:. * * : * :::* :.: * .* ** :.: * **:*:: * ** :.** * *.:*.: :::*.**::.:.* * *.*:* :. ** ::.* . :..*...* * :*: *: :. :**:* : : :******:::: *** **..*:::**: : :** *.::: *: ..* :::: . .**. :* * *:*****:*: *: *.: ::. *.:*: : : ***:*:.:*.* * * :: :.:*: :*: **.* : *** .::. * .* ** * *::**:**:***:* * . **** * .* .*::*:.** ***::****.*:*:*:.: *. : . *******: : .* *** * : ::* :. ** . ::.****:*:*:::.*:::*:::*:*:* **** ::** * ::. *. *:**::.* .: :::::* .:*.*:. :**: **. *.* * *:*:** .*:***:*:***:*:** ****:.**: :.*.*:****:*****::*:**:.*: :*::**: *:***** :******.** ***: ***:****:* .*:.:* **:* :.:.::***::: .********: **:.*.***:*.*.* *:*************:******:**:***..**:*:*********:*: *****:**:****:***:**:", "identical_positions": 754, "similar_positions": 571, "identity": "30.93%" }, { "cls_id": "homologset.agr.RGD:621058", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P00770-1", "uniprot_id": "MCPT2_RAT", "id": "P00770-1", "name": "Mast cell protease 2", "aln": "----MQALLFLMALLLP-----------SGAGAEEIIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGR----EITVILGAHDVRKRESTQ--------QKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIH--PGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKFQVCVGSPTTLRAAFM-GDSGGPLLCAGVAHGIVSYGHPD--------AKPPAIFTRVSTYVPWINAVINTSS-----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11034-1", "uniprot_id": "MCPT1_MOUSE", "id": "P11034-1", "name": "Mast cell protease 1", "aln": "----MQALLFLMALLLP-----------SGAGAEEIIGGVEARPHSRPYMAHLKIITDRGSEDRCGGFLIAPQFVLTAAHCKGR----EITVTLGAHDVSKSESTQ--------QRIKVEKQIIHKNYNVSFNLYDIMLLKLEEKAELTPTVDVIPLPGPSDFID--PGKMCWTAGWGKTGEKEPTSETLREVELRIMDKEACKMYKHYDYNFQVCVGSSTKLKTAYM-GDSGGPLLCAGVAHGIVSYGDSH--------GKPPAVFTRISAYVPWIKTVINGK------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PUX6-1", "uniprot_id": "A0A8M1PUX6_DANRE", "id": "A0A8M1PUX6-1", "name": "trypsin", "aln": "----MQYIMLLCVFLLLSL------FSLSGGLESGIVGGREAKHHSRPYMASLQKKRN----HVCGGMLIKEDYVLTSAHCWNETDKYSLQIVLGAHNISQKENSQ--------QIIQVEKYIKHRKF-------DIMLLKLRTKAVLNHFVDIINLPKHEISIL--APLECSIAGWGMKRPGEGASNVLRVVNLQLESNAKCKSKWQTHFNFKNMVCTVSDGKKAFCQGDSGSPLLCNSELYGMAAYTYPKNCT----FKEYPEVYMKVSAFLPWIKKNIQ--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZA42-1", "uniprot_id": "A1ZA42_DROME", "id": "A1ZA42-1", "name": "Peptidase S1 domain-containing protein", "aln": "MSNFIIGIAVICCLWRRVQGFQMLLEEDCGIPHNISERSVNAKLAQNPWMAYLETPKG----FHCSGTLINHLFVLTAAHCVPD--DLLITVRLGEYNTKTKVDCDNHLCQEPFQEYNVDMGFRHRYYNANDQTNDIGMLRLGRRVEYLNHIRPICIFASNRFQEPIDQLTWFTTTVWRETAANATSKVLRTMNIDRQPKETCSEIYGWNMTFEQICAGNT--LSQLCSTDSGAPQIRKMWHNGSDRYVQLGIASRVKGQCQNSGILMDLLSYADWIKRVVRQYGPSTDMNRSLKKWVDKIPVFYYPK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: : .* . . :: ..*:** *. *.* ** :***:*** : : ** :: . : * :*: : *. : ** :*:* :. : : : . : : :* .** ::: : * . .*: : ***.* : * * : . : : :: **: :. ", "identical_positions": 37, "similar_positions": 59, "identity": "12.01%" }, { "cls_id": "homologset.agr.RGD:621059", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JVY9-1", "uniprot_id": "A0A0G2JVY9_RAT", "id": "A0A0G2JVY9-1", "name": "Cyclin-A2", "aln": "-MPGNSRQ------AGSALLS-----QQEDQENVNPEKVAPAQQPR---AQAVLKAGKVRGPAPQQRLKTRR-VAPLKDLPINDEHVPTVPSWKAVSKQPAFTIHVDEAE-ETQKRPAEQKETQCEDALAFSAAVSLPGARKPLVPLDYPMDGSFESPHAMDISIVLEDEKPVNVN----------------------EVPDYHEDIHTYLREMEVKCKPKVSYMKRQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFDLAAPTVNQFLTQYFLHLQPANCKVESLAMFLGELSLIDADPYLKYLPSLIAGAAFHLALYTVTGQSWPESLVQKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKHSKYHSVSLLNPPETLNV-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51943-1", "uniprot_id": "CCNA2_MOUSE", "id": "P51943-1", "name": "Cyclin-A2", "aln": "-MPGTSRHS--GRDAGSALLSL----HQEDQENVNPEKLAPAQQPR---AQAVLKAGNVRGPAPQQKLKTRR-VAPLKDLPINDEHVTAGPSWKAVSKQPAFTIHVDEAE-ETQKRPAELKETECEDALAFNAAVSLPGARKPLTPLDYPMDGSFESPHAMDMSIVLED-KPVNVN----------------------EVPDYQEDIHTYLREMEVKCKPKVGYMKRQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFDLAAPTVNQFLTQYFLHLQPANCKVESLAMFLGELSLIDADPYLKYLPSLIAGAAFHLALYTVTGQSWPESLAQQTGYTLESLKPCLVDLHQTYLKAPQHAQQSIREKYKHSKYHSVSLLNPPETLSV-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20248-1", "uniprot_id": "CCNA2_HUMAN", "id": "P20248-1", "name": "Cyclin-A2", "aln": "-MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQRPKTRR-VAPLKDLPVNDEHVTVPP-WKANSKQPAFTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIILEDEKPVSVN----------------------EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14785-1", "uniprot_id": "CCNA_DROME", "id": "P14785-1", "name": "G2/mitotic-specific cyclin-A", "aln": "MASFQIHQDMSNKENPGIKIPAGVKNTKQPLAVIGGKAEKNALAPRANFAVLNGNNNVPRPAGKVQVFRDVRNLNVDENVEYGAKKSNVVPVVEQFKTFSVYEDNNDTQVAPSGKSLASLVDKENHDVKFGAGQKELVDYDLDSTPMSVTDVQSPMSVDRSILGVIQSSDISVGTETGVSPTGRVKELPPRNDRQRFLEVVQYQMDILEYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTPTAYVFINTYAVLCDMP-EKLKYMTLYISELSLMEGETYLQYLPSLMSSASVALARHILGMEMWTPRLEEITTYKLEDLKTVVLHLCHTHKTAKELNTQAMREKYNRDTYKKVAMMESVEMSKDDFDQLCEAYNCKQKEDEHQQPDINTKSNVNLFYKF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. :: :. : . ** * : . * . * : * : ::: . :: . * : .. ..: : * : * *. . : .*. . .* . .*:. . * * . :.:: .. .*..: ** :*: ** *:** * * :** **::* **::.**:**:******.*****:.***:*:* *:*****.*:*:*.********** :*:*:********.***::***:*:* ******:::**:*:***.:**. *:. * : : . *:: :::::.****::.:.**:****:::.*:. ** : : : *. * . * *.**.**. ::.* :*: .* : *::****:...*: *::::. * . ", "identical_positions": 139, "similar_positions": 142, "identity": "28.25%" }, { "cls_id": "homologset.agr.RGD:621060", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88777-1", "uniprot_id": "PSN2_RAT", "id": "O88777-1", "name": "Presenilin-2", "aln": "--MLTFMASDSE----EEVCDERTSLMSAE---SPTSRSCQD----SRPGPEDGENTAQWRSQENEDDCEEDPDHYACSGV-PGRPSG--LEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLD-PSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAP------------------------------------------------------------------------------QPGYPGEEPEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61144-1", "uniprot_id": "PSN2_MOUSE", "id": "Q61144-1", "name": "Presenilin-2", "aln": "--MLAFMASDSE----EEVCDERTSLMSAE---SPTSRSCQE----GRPGPEDGESTAQWRTQESEEDCEEDPDRYACSGA-PGRPSG--LEEELTLKYGAKRVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLD-PSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAP------------------------------------------------------------------------------LPGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWNTTLACFIAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49810-1", "uniprot_id": "PSN2_HUMAN", "id": "P49810-1", "name": "Presenilin-2", "aln": "--MLTFMASDSE----EEVCDERTSLMSAE---SPTPRSCQE----GRQGPEDGENTAQWRSQENEEDGEEDPDRYVCSGV-PGRPPG--LEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQ-LIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLD-PSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPP------------------------------------------------------------------------------LTGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90ZE4-1", "uniprot_id": "PSN2_DANRE", "id": "Q90ZE4-1", "name": "Presenilin-2", "aln": "-----MNTSDSE----EDSYNERSALVQSE---SPTVPSYNQDNAMSLPQDTDSKRSGAVRSRSASGSGDAGP---VDRER-ADTPDG--EEEELTLKYGAKHVIMLFIPVTLCMVVVVATIKSVSFYTEKSGQRLIYTPFEEDPNSVGQRLLNSVLNTLVMISVIVFMTIILVLLYKYRCYKFIHGWLILSSLMLLFWFSFMYLGEVFKTYNVAMDYPTLLMIIWNFGVVGMICIHWKGPLRLQQAYLIVISALMALIFIKYLPEWSAWVILGAISIYDLIAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWMVGMADSNNPDSAGERRRSGGGVRTQE-----GVESEHDAPQAG------------------------------------------------------------------------------RRQYSAEE-DLEEDRGVKLGLGDFIFYSVLVGKAAATG-GDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFSTDNLVRPFMDSLAAHQYYI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O02194-1", "uniprot_id": "PSN_DROME", "id": "O02194-1", "name": "Presenilin homolog", "aln": "MAAVNLQASCSSGLASEDDANVGSQIGAAERLERPPRRQQQRNNYGSSNQDQPDAAILAVPNVVMREPCGSRPSRLTGGGGGSGGPPTNEMEEEQGLKYGAQHVIKLFVPVSLCMLVVVATINSISFYNSTDVY-LLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVNTVTPQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAASGQRTGNSHPRQNQRDDGSVLATEGMPLVTFKSNLRGNAEAAGFTQEWSANLSERVARRQIEVQSTQSGNAQRSNEYRTVTAPDQNHPDGQEERGIKLGLGDFIFYSVLVGKASSYG--DWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* *. *: : : : :* *. . : . . . * . .. * *** *****::** **:**:***:******:*: **.... *:**** *:. . . :: .:: *:*:::**:*.**::*::*** ***::******:**:**** *:::** *::::**:.***** :: :****.***:.***:*** ***.***.::*****:********:**.:*.***::**:***.*:****:********** *********::*: : : .. . . . : :. . :. : :*:**:*****************:: * **.**:***:**************:::**************:* *:*. :*:***: *:::* :*", "identical_positions": 210, "similar_positions": 121, "identity": "38.6%" }, { "cls_id": "homologset.agr.RGD:621061", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHK4-1", "uniprot_id": "KAT5_MOUSE", "id": "Q8CHK4-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------MAEVG-EIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLK-SESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSK---RGKW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99MK2-1", "uniprot_id": "KAT5_RAT", "id": "Q99MK2-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------MAEVG-EIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGSARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLK-SESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSK---RGKW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92993-1", "uniprot_id": "KAT5_HUMAN", "id": "Q92993-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------MAEVG-EIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERLDL-KKIQFPKKE-AKTPTKNGLPG-----------SRPGSPEREVP---------ASAQASGKTLPIPVQITLRFNLPKEREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSP-ATPVPSETAPASVFPQNGAARRAVAAQPGRKRKSNCLGTD---------------------EDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLT-----------------KCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLK-SESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTPKDWSK---RGKW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QDW0-1", "uniprot_id": "A0A8M9QDW0_DANRE", "id": "A0A8M9QDW0-1", "name": "Histone acetyltransferase KAT5", "aln": "---------------MAEPTVEIVEGCRLPVLRKNQENEDEWPLAEILSVKDIPGRKLYYVHYIDFNKRLDEWVTPDRLDL-KKLQFPKKE-AKTPTKNGLPG-----------SRPSSPEREVRKSLDLNVQSASAPSRGKTLPTPKRKAESVSLATQ---VTAATPVPSLPSS--AEASQASVYPAMRDSSF-SIKAREEHEQLTSLTTNGTTRRLIPSQPGRKRK-NCVGTEEIVKVFQNNSPRSSTVYLPPGEDSQDSSDGIPSAPRMTGSLVSDRSHDDIITRMKNIDCIELGRHRLKPWYFSPYPQELTTLPILYLCEFCLKYLKSLKCLQRHLVRAVLGPDVTHSQHQIKTKCNLRHPPGNEIYRKGTISFFEIDGRKNKMYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDSKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMNLK-SENGERPQMTINEISEITSVKKEDVISTLQYLNLINYYKGQYILTLSEDIVEGHERAMHKRHLRIDSKCLHFTPKDWSK---RGKW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q960X4-1", "uniprot_id": "TIP60_DROME", "id": "Q960X4-1", "name": "Histone acetyltransferase Tip60", "aln": "MKINHKYEFDDDVASICESTAALTEGCRLPVR---MHKTDDWPLAEIVSIKELDGRRQFYVHYVDFNKRLDEWVNEEDLYT-RKVQFPRRDGSQTGTSTGVTTPQRHHSLAGSVSRPTSPQHPGSG----ALAAIPQTPTGASGSVPPPAGIPNSVAPPGTPSSGGELVNGNNLAAALQKRINRKRKNHGGSAHGHHSLTSQQQQSHPHPTTPQTPTATPVHVTGDGLISGAAND----------------------DGDGSQDGKTPTPRQSGSMVT--HQDDVVTRMKNVEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLS-----------------KCNLRHPPGNEIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHIVGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGLLSYRSYWAQTILEIFISQNPSTDGEKPTITINDICECTSIKKEDVISTLQNLNLINYYKGQYIVCINRVIIEQHRRAMDKRKIRIDSKCLHWTPKDWSK---RSK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08649-1", "uniprot_id": "ESA1_YEAST", "id": "Q08649-1", "name": "Histone acetyltransferase ESA1", "aln": "--MSHDGKEEPGIAKKINSVDDIIIKCQCWVQ-----KNDEERLAEILSINTRKAPPKFYVHYVNYNKRLDEWITTDRINLDKEVLYPKLK--------------------------------------------------------------------------------------ATDEDNKKQKKKKATNTSETPQDSLQDGVDGFSRENTDVMDLDN-------LNVQGIK----------------------DENISHEDEIKKLRTSGSMTQN---PHEVARVRNLNRIIMGKYEIEPWYFSPYPIELTDEDFIYIDDFTLQYFGSKKQYERYRK-----------------KCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHLVGYFSKEKESADGYNVACILTLPQYQRMGYGKLLIEFSYELSKKENKVGSPEKPLSDLGLLSYRAYWSDTLITLLVEHQ-------KEITIDEISSMTSMTTTDILHTAKTLNILRYYKGQHIIFLNEDILDRYNRLKAKKRRTIDPNRLIWKPPVFTASQLRFAW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *: * : *: ****:*:: . :****:::*******:. : : ::: :*: . . . . . . * : * :. * :**:. . ::*::*:: * :*::.::******** ** :*: :* *:* * * :*: ** ***********. :*********:: :.:*****:* **********.****** **. * *.*:**********::.********:* *** *************** *.*.*:**************:**::*:: ::: : :**::*.. **:.. *:: * : **::.*****:*: :.. *:: :.* *: **.: * :.* :: * ", "identical_positions": 175, "similar_positions": 111, "identity": "29.46%" }, { "cls_id": "homologset.agr.RGD:621062", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10716-1", "uniprot_id": "CLC4F_RAT", "id": "P10716-1", "name": "C-type lectin domain family 4 member F", "aln": "MKEAELNRDVAKFCTDNQCVILQPQGLGPKSAAPMAPRTLRHVQAIVALVVVTVFFSLLALFVVVLQPWRQKQNEDHPVKAGLHGGNYSGS-----DNCSQFVRRAEMQEAIQSLRASG-NSSSCHKEIQTLKYQMDNVSSQVQLLGGHLEEANADIQQAKDVLKGTGALASETQALRSSLEVASADIHSLRGDLEKANAMTSQTQGLLKSSTDNTSAELHVLGRGLEEAQSEIQALRGSLQSS-----------------------------------------------------------NDLGSRTQNFLQHSMDNISAEIQAMRDGMQRAGEEMTSLKKDLETLTAQIQNANGHLEQTDTQIQGLKAQLKSTSSLNSQIEVVNGKLKDSSREL--QTLRRDLSDVSALKSNVQMLQSNLQKAKAEVQSLKTGLEATKTLAAKIQGQQSDLEALQKAVAAHTQGQKTQNQVLQLIMQD-WKYFNGKFYYFSRDKKS-WHEAENFCVSQGAHLASVTSQEEQAFLVQITNA-----VDHWIGLTDQGTEG-NWRWVDGTPFDYVQSRRFWRKGQPDNWRHGNGEREDCVHLQRMWNDMACGTAYNWVCKKSTDWSVARTDQS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70194-1", "uniprot_id": "CLC4F_MOUSE", "id": "P70194-1", "name": "C-type lectin domain family 4 member F", "aln": "MKEAELNRDMARYCTDNQCVSLQPQGLGPKSAALMAPRTLRHVQVILALMVVTVIFSLLALFVVASQPWRPEWNKEPPSLL-LRGSNNSGH-----DNHSQFVRETEMQVAIQRLRDYEENSSSCHKEVQILKYQMDNVSSLVQLLGSHLEDVNADILQTKDVLKESGALALETQALRSSLEVASADIHSLRGDLEKANAMTSQTRGLLKSSTENTSAELHVLGRGLEEAQSEIQALRGSLQSA-----------------------------------------------------------NDLSSQTQGFLQHSMDNISAQIQTVRDGMERAGEKMNSLKKELETLTAQTQKANGHLEQTDAQIQGLKAELKSTSSLNSRIEVVNGQMKDASREL--QTLRRDLSDVSALKSNVQMLQSNLQRAKTEMQTLKADLQATKALTAKIQGEQNRLGALQEAVAAQKQEQKTQNQVLQLIAQN-WKYFNGNFYYFSRDKKP-WREAEKFCTSQGAHLASVTSQEEQAFLVQTTSS-----GDHWIGLTDQGTEG-IWRWVDGTPFNNAQSKGFWGKNQPDNWRHRNGEREDCVHVRQQWNDMACGSSYPWVCKKSTGWSAARVG----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N1N0-1", "uniprot_id": "CLC4F_HUMAN", "id": "Q8N1N0-1", "name": "C-type lectin domain family 4 member F", "aln": "-----MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVVQQQTRP---VPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREI--QTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQG-WKFNGGSLYYFSSVKKS-WHEAEQFCVSQGAHLASVASKEEQAFLVEFTSK-----VYYWIGLTDRGTEG-SWRWTDGTPFNAAQNK-------------APGSKGSCPLRKYIIVNSGMG-ACSFIDTPPCPWILSN------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RLL2-1", "uniprot_id": "A0A8M1RLL2_DANRE", "id": "A0A8M1RLL2-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAVYENVECR---------DIKNSTGPQSQNHNRDEENDRKRRRWKCVVLVIMGLICALLLLFITLQNIS-------ITAERDLFKTYKNTVEELNHTISSLQHDNTDLETDKQQLEDKYNSLSLKKQQLETKYNSLSLGKQQLENRVTSLSAELKE-ARSKSG-WFFMSTEAMS-WSESRQFCRDRGADLVIIKSEEKQRFISSLVK------EDTWIGLSVTETGGNKWKWVDNSPLN----QGFWAKGEPNN---YQGAKEDCVEVR-----ISQGTPNNWNDRRCSDSRKAVCEK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z340-1", "uniprot_id": "A0A8M6Z340_DANRE", "id": "A0A8M6Z340-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSVYENSRIVLSTVASNENSRNE-------GNHSYEQESEREVNTAKWNKLLLTVFAVSLVFALGGLCVVSILYVRALTQQS---------AQTNTKIMKRQLEELTANCSRVKDDLYIKDSMMKDLTANYSRVKDDLHIKDSMVKELTANNSRIKEQQSFYKAFRASNMTAFQGKLYFFSSDKLT-WSSSRAFCVSRGTDLVTITSRSEQAFLQSKMN------EWTWIGLSDLETEG-RWVWVNNQTLNDTG-VEFWYKRQSGKSEPDNWTKDDPSGEHCAIVKYALNYLKSWFDVSCEHTYKFICEKKI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRH8-1", "uniprot_id": "Q8IRH8_DROME", "id": "Q8IRH8-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIRPTLIVVLISLASVDSGHNSPVTTIPVAEPISQVPHGFQLGQNNHISSSSNISRSGGGNGRDKRGAQLD--------------------------------------------------------------------------PSEIARQNQITQQIFANYLERRLFPNRTANQKIPTIADILPKPKPSPRPRPRGFAASDGGNFKRSGGGAQRNRLAAAASKRQSGYNRKRLREEQEEEEEADDQERDQQPLANQEDFDYDVQESLQSVESEQHDQYYGNIFHRDPSENEVDNDCPNCVDESQYTPNKWTMPLLKLGEKRYYLGIFFKANWFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLGHEHFWISGTDLADEGNFFWMATGRPITFTN----WNAGEPNNFRYENGEEENCLELWN-----RDGKGLKWNDSPCSFETYFVCEVQPN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . : . . . . . : . . . : . :::. . * .: :* :* .*. : *..:: : . **. : * : . . .: . . . : ", "identical_positions": 8, "similar_positions": 46, "identity": "1.28%" }, { "cls_id": "homologset.agr.RGD:621063", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07141-1", "uniprot_id": "CSF1_MOUSE", "id": "P07141-1", "name": "Macrophage colony-stimulating factor 1", "aln": "MTARGAAGRCPSSTWLGSRLLLVCLLMSRSIAKEVSEHCSHMIGNGHLKVLQQLIDSQMETSCQIAFEFVDQEQLDDPVCYLKKAFFLVQDIIDETMRFKDNTPNANATERLQELSNNLNSCFTKDYEEQNKACVRTFHETPLQLLEKIKNFFNETKNLLEKDWNIFTKNCNNSFAKCSSRDVVTKPDCNCLYPKATPSSDPASASPHQPPAPSMAPLAGLAWDDSQRTEGSSLLPSELPLRIEDPGSAKQRPPRSTCQTLESTEQPNHGDRLT-EDSQPHPSAGGPVPGVEDILESSLGTNWVLEEASGEASEGFLTQEAKFSPSTPVGGSIQAETDRPR-ALSAS-PFPKSTEDQKPVDITDRPLTEVNPMRPIGQTQNNTPEKTDGTSTLREDHQEPGSPHIATPNPQRVSNSATPVAQLLLPKSHSWGIVLPLGELEGKRSTRDRRSPAELEGG--------------------------SASEGAARPVARFNSIPLTDTGHVEQHEGSSDPQIPESVFHLLVPGIILVLLTVGGLLFYKWKWRSHRDPQTLDSSVGRPEDSSLTQDEDRQVELPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8JZQ0-1", "uniprot_id": "CSF1_RAT", "id": "Q8JZQ0-1", "name": "Macrophage colony-stimulating factor 1", "aln": "MTARGAAGRCPSSTWMGSRLLLVCLLVSRSVA-EVSEHCSHMIGNGHLQILQQLIDSQMETACLIEYKFVDQEQLDDPVCYLKKAFVLVQVIIEETMRFKDNTPNANATERLQELSMKLNSCFIKDYKEQNEACVQTYKESPLRLLEKIKNFFNETKNFLEKDWNIFSKNCNDSFAKCSSRDVVTKPDCNCLYPKATPSSDLASASPHQPPAPSMAPLADLAWDDSQRTEGSSLLPSDLPLRIEDPGSAKQRPPRSTCQTLESTEQPNH------EDPQPHPSAGAPIPGVEDIIESSMGTNWVLEEASGEASEGFLTQERKFSPSNPVGGSIQAETDRPW-ARSASSPFPKLTEDQQPTNITDTPLTEVNPMRPTGQTLNNTPEKTDGSSTLREDQQEPRSPHFATLNPQRVGNSATPYAKLLPPKSHSWGIVLPLGELEGKKSTRDRRSPAELKGGPASEGAARPVAQSTRDRRSPAELKGGPASEGAARPVARFNSIPLTDTGSSIQ-----DPQT--SAFVFWVLGIILVLLAVGGLLFYSWKRRSHRDPRTLDSSVGRPEGSSLAQDEDRQVELPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09603-1", "uniprot_id": "CSF1_HUMAN", "id": "P09603-1", "name": "Macrophage colony-stimulating factor 1", "aln": "MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQMETSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLKSCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSSQDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQPLHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMGTNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPADVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLSAQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGG--------------------------PASEGAARPLPRFNSVPLTDTGHERQSEGSFSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEGSPLTQD-DRQVELPV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *******.:**:** ******* ***:: ****:******.***: **:********:* * ::*******.**********.*** *:::****:****** * :***** .*:*** ***:*:::***:*: *:**:****:**.******:*:******:****:***:***:*************** **** **.***** ******:*.*:*:**: ********.: **: ***************::*..* * ..**:**.*. **:***::*::***** ********* :.* ::*** * ***:*:*. ** *** *:* ::.*:*.::*. .*..*.*:** ** *:**:*** .*:* .* ** **:::: .** :.*.:* *: .:*** * *********::********** :** .********:.****:****** * .** *.* : * .:*****:******* *: ***::*: **.: :**.*.*:** ********", "identical_positions": 347, "similar_positions": 121, "identity": "59.72%" }, { "cls_id": "homologset.agr.RGD:621064", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D939-1", "uniprot_id": "ST1C2_MOUSE", "id": "Q9D939-1", "name": "Sulfotransferase 1C2", "aln": "----------------------------MALTPELSRQTKLKEVAGIPLQAPTVDNWRQIQTFEAKPDDLLICTYPKSGTTWIQEIVDMIEQNGDVEKCRRTIIQHRHPFIEWARPPQP---SGVDKANEMPAPRILRTHLPTQLLPPSFWTNNCKFLYVARNAKDCMVSYYHFYRMSQVLPEPGTWDEYFETFINGKVSWGSWFDHVKGWWEIRDKYQILFLFYEDMKRNPKHEIQKVMQFMGKNLDEDVVDKIVLETSFEKMKENPMTNRSTAPKSILDQS-----ISPFMRKGTVGDWKNHFTVAQNERFDEIYKQKMGRTSLNFSMEL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WUW8-1", "uniprot_id": "ST1C2_RAT", "id": "Q9WUW8-1", "name": "Sulfotransferase 1C2", "aln": "----------------------------MALAPELSRQTKLKEVAGIPLQAPTVDNWSQIQTFKAKPDDLLICTYPKSGTTWIQEIVDMIEQNGDVEKCQRTIIQHRHPFIEWARPPQP---SGVDKANAMPAPRILRTHLPTQLLPPSFWTNNCKFLYVARNAKDCMVSYYHFYRMSQVLPDPGTWNEYFETFINGKVSWGSWFDHVKGWWEIRDRYQILFLFYEDMKRDPKREIQKVMQFMGKNLDEEVVDKIVLETSFEKMKENPMTNRSTVPKSVLDQS-----ISPFMRKGTVGDWKNHFTVAQNDRFDEIYKQKMGGTSLNFCMEL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00338-1", "uniprot_id": "ST1C2_HUMAN", "id": "O00338-1", "name": "Sulfotransferase 1C2", "aln": "----------------------------MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQP---SGVEKAKAMPSPRILKTHLSTQLLPPSFWENNCKFLYVARNAKDCMVSYYHFQRMNHMLPDPGTWEEYFETFINGKVVWGSWFDHVKGWWEMKDRHQILFLFYEDIKRDPKHEIRKVMQFMGKKVDETVLDKIVQETSFEKMKENPMTNRSTVSKSILDQS-----ISSFMRKGTVGDWKNHFTVAQNERFDEIYRRKMEGTSINFCMEL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1L8-1", "uniprot_id": "Q9W1L8_DROME", "id": "Q9W1L8-1", "name": "", "aln": "MPQSSFFAKSVPFEQIDKLAISGGYSSIFASSKPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCGTTWMQELAWLVINECDFETAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWMLPRQIWSKRPKIIYVYRNPKDAAIS--YFHHWRGMVGYQGTKSDFMHSFIDGYVNFTPCWPHILDFWQLRHEPNIFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVKEFESMKAAAGREVEEFRFVRRGVVGSHKDELTADIIREFDLWSDSNLRDFKLNMDDFANYSKFAST------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KF40-1", "uniprot_id": "A0A0B4KF40_DROME", "id": "A0A0B4KF40-1", "name": "", "aln": "---------------MNRVQVTP-------RSYPTNLIDKDWGNRKLFYTKDSENFLRLVHDMKLRDDDVWIVTLPKCGTTWMQELLWLLLNNCDFEGALAKDQELRTPFLEFGYSVFHDPNRSFGPIEDLKSPRLIKSHLSLALLPSKLWEGKNKVIYVSRNPLDSYVSR-YYHGVSFGFNYGKSLHQYFDEVLASDDFPTEFIEHAHEFYQLRNEPWVFYTSFEMMKKDLRGVINDVSRFLNKPINDQQMEKLLKHLSFAEMKKNPTTNHLWELAQVQHEN-AGKEMHPFVRRGDVNGYKDELKPEQIEKANVRIQEVLAKNGVTLDELLLLKDQDWPCSGLCTQHSQTNSEAITLRNGPKAHQHQCSSACTRWLCVRVKVVKAESRGRTGPILMLMQGSRDAEMPTPPPQREAKNGKQATFIAGREVFTVLWERRISQDVNRGSCTMFAPHSLPVTSRLLLLVVTLLFCPVQAHLSKRSYSDQSVHGYMTERTCWWNEVCKEEFQSLFRCKCPQFSYCRSPGRYYNAYCSMTDTGYIWTQPNWDWGA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: : **: * * **.****:**: :: :: *.* . * **:*: . : : :**::::**. :** .:* . *.:** **. *. :* :: . : :::. .: . * :::::.. ::: :* :* : * .* :*: : :.: :::: . ** .*:.** *: .: *:*:* *.. *:.:. . : : :.: ", "identical_positions": 49, "similar_positions": 91, "identity": "8.91%" }, { "cls_id": "homologset.agr.RGD:621065", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01587-1", "uniprot_id": "CSF2_MOUSE", "id": "P01587-1", "name": "Granulocyte-macrophage colony-stimulating factor", "aln": "MWLQNLLFLGIVVYSLSAPTRSPITVTRPWKHVEAIKEALNLLDDMPVTLN---EEVEVVSNEFSFKKLTCVQTRLKIFEQGLRGNFTKLKGALNMTASYYQTYCPPTPETDCETQVTTYADFIDSLKTFLTDIPFECKKPGQK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48750-1", "uniprot_id": "CSF2_RAT", "id": "P48750-1", "name": "Granulocyte-macrophage colony-stimulating factor", "aln": "MWLQNLLFLGIVVYSFSAPTRSPNPVTRPWKHVDAIKEALSLLNDMRALENEKNEDVDIISNEFSIQRPTCVQTRLKLYKQGLRGNLTKLNGALTMIASHYQTNCPPTPETDCEIEVTTFEDFIKNLKGFLFDIPFDCWKPVQK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P04141-1", "uniprot_id": "CSF2_HUMAN", "id": "P04141-1", "name": "Granulocyte-macrophage colony-stimulating factor", "aln": "MWLQSLLLLGTVACSISAPARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVISEMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLTMMASHYKQHCPPTPETSCATQIITFESFKENLKDFLLVIPFDCWEPVQE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.**:** *. *:***:*** . *:**:**:**:** **: * *:::*: *.::. **:****::::*****.:***:*.*.* **:*: *******.* :: *: .* ..** ** ***:* :* *:", "identical_positions": 71, "similar_positions": 41, "identity": "49.31%" }, { "cls_id": "homologset.agr.RGD:621066", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6T4-1", "uniprot_id": "EMAL2_RAT", "id": "Q6P6T4-1", "name": "Echinoderm microtubule-associated protein-like 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSFGTGKTKEVIFSMEEGSVKMFLRGRPVPMLIP----DELAPTYSLDTRSELPSSRLKLDWVYGYRGRDCRANLYLLPTGEVVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAVHPDMVTIATGQVAGTTKEGKPLPPHVRVWDSVSLSTLHVLGLGVFDRAVCCVAFSKSNGGNLLCAVDESNDHVLSVWDWAKESKVVDSKCSNEAVLVATFHPTDPNLLITCGKSHIYFWSLEGGNLSKRQGLFEKHEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKG--GNRITQEVLGAHDGGVFALCALRDGTLVSGGGRDRRVVLWG--SDYSKVQEVEVPEDFGPVRTVAEGR----GDTLYVGTTRNSILLGSVHTGFSLLVQGHVEELWGLATHPSRAQFVSCGQDKLVHLWSSETHQPVWSRSIEDPARSAGFHPSGSVLAVGTVTGRWLLLDTDTRDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSTCFVTNSGDYEILYWDAATCKQITSADTVRNVQWATATCVLGFGVFGIWP---EGADGTDINAVARSHDGNLLVSADDFGKVHLFSYPCCQPRALSHKYGGHSSHVTNVAFLWDDSMVLTTGGKDTSVLQWRVA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TNG5-1", "uniprot_id": "EMAL2_MOUSE", "id": "Q7TNG5-1", "name": "Echinoderm microtubule-associated protein-like 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSFGIGKTKEVIFSMEEGSVKMFLRGRPVPMLIP----DELAPTYSLDTRSELPSSRLKLDWVYGYRGRDCRANLYLLPTGEVVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAVHPDMVTIATGQVAGTTKEGKPLPPHVRVWDSVSLSTLHVLGLGVFDRAVCCVAFSKSNGGNLLCAVDESNDHVLSVWDWAKESKVVDSKCSNEAVLVATFHPTDPSLLITCGKSHIYFWSLEGGSLSKRQGLFEKHEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKG--GNRITQEVQGAHDGGVFALCALRDGTLVSGGGRDRRVVLWG--SDYSKVQEVEVPEDFGPVRTVAEGR----GDTLYVGTTRNSILLGSVHTGFSLLVQGHVEELWGLATHPSRAQFVTCGQDKLVHLWSSETHQPVWSRSIEDPARSAGFHPSGSVLAVGTVTGRWLLLDTETHDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSTCFVTNSGDYEILYWDPVTCKQITSADTVRNVEWATATCVLGFGVFGIWP---EGADGTDINAVARSHDGKLLVSADDFGKVHLFSYPCCQPRALSHKYGGHSSHVTNVAFLWDDSMALTTGGKDTSVLQWRVA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95834-1", "uniprot_id": "EMAL2_HUMAN", "id": "O95834-1", "name": "Echinoderm microtubule-associated protein-like 2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSFGAGKTKEVIFSVEDGSVKMFLRGRPVPMMIP----DELAPTYSLDTRSELPSCRLKLEWVYGYRGRDCRANLYLLPTGEIVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAIHPDMVTIATGQVAGTTKEGKPLPPHVRIWDSVSLSTLHVLGLGVFDRAVCCVGFSKSNGGNLLCAVDESNDHMLSVWDWAKETKVVDVKCSNEAVLVATFHPTDPTVLITCGKSHIYFWTLEGGSLSKRQGLFEKHEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKG--GNRITQAVLGAHDGGVFGLCALRDGTLVSGGGRDRRVVLWG--SDYSKLQEVEVPEDFGPVRTVAEGH----GDTLYVGTTRNSILQGSVHTGFSLLVQGHVEELWGLATHPSRAQFVTCGQDKLVHLWSSDSHQPLWSRIIEDPARSAGFHPSGSVLAVGTVTGRWLLLDTETHDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSSCFVTNSGDYEILYWDPATCKQITSADAVRNMEWATATCVLGFGVFGIWS---EGADGTDINAVARSHDGKLLASADDFGKVHLFSYPCCQPRALSHKYGGHSSHVTNVAFLWDDSMALTTGGKDTSVLQWRVV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUI3-1", "uniprot_id": "EMAL_DROME", "id": "Q9VUI3-1", "name": "Echinoderm microtubule-associated protein-like CG42247", "aln": "MPQISPNAPLEGNVSPPPTQPHLDDNLHNGNGNGNGIHSSSSNINKHGSNINGNNDSNRSSPAKSPKRPVSSSFRIQNTSRYDNDEEDLAASEQVAGGDRQVPDYWQQRNGATTGATSGRQSRAISPGYLDNMSENSEQPPVVPLVRSKSRPEISSAAASRYNNLSYWKARRVVFYRNGDPFFPGVELRYRPGRDVTSLDNLLDKISPKMDLPRGARYVFSMDGDRKYHLDELEDGAFYVVSSFKAFKPASYGKKNGMWYASPGNQGWGSKPASRKPSIMEADLGTLSTTSGSIKRSAGRVIRIINNLDHSVQCRVLLNLRTSQPFEEVLEDLGQVLKINGAKKMYTGTGQEVRSFSQLRNEFADVDTFYLATGTALIAGSPIRRSRSRPSVVAAAPILPTDELPKVPLRGARPRSKSRPRILYAPESEILRPNGEYTMLDIMKEEPTKVTIRGLRRTFYPPVHHAPADNSPPDKKLQLQWVHGYRGIDARRNLWVLPSGELLYYVAAVAVLFDRDEDAQRHYTGHTEDIMCMDVHPSRELVASGQKAGRDRKSQ---AHVRIWSTESLQTLYVFGMGELDSGVTAVAFSQLNGGSYILAVDSGRESILSVWQWQWGHLLGKVATLQEGLSGAAFHPLDDNLIITHGRGHLAFWHRRKDGFFERTDIVKQPSRS-HVTSVQFEPDGDVITADSDGFITIYSVDSDGAYFVRTEFEAHNKGIGCLIMLGEGTLLSGGEKDRKIAAWDSLQNYKKIADTKLPEAAGGVRTIYPQRPGRNDGNIYVGTTRNNILEGSLQRRFTQVVFGHGRQLWGLAAHPDDELYATAGHDKHVALWR--KNKLIWTIQTGYECVALAFHPFG-TLAAGSTEGHLLVINCENGAVMLTLRVCGSPLNCVAYNQVGDMIAMGSQNGSIYLFRVSRDGFSYKKVNKIRG-SQPLTHLDWSMDGNFVQTVTIDFDLLFWDAKSLSPERSPIAMKDVKWLTNNCTVGFLVAGQWSNRYYSTTNTIVATCSRSAAHDMLASGDAEGYLRLFRYPCISPRAEFHESKVYSGMLACVRFLCGDHTLITVGGTDASLMVWDIVEE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . .*:: . : :: ::: .*. : * .*.: : .. *. :*:*:**:**** *.* **::**:**::*:**:****:. :*: **** **.:** *: :**. :*:** ** ::.: .***:*.: **.**:*:*:* :* .* .*.**: ***. : ***...: :****:* : . :*.: *:*** * .::** *:.*: ** . ..: :* .:.:: .:. :* .* * .***:*.**.* : ::. . * :.: **: *: * * :***:*** :**::. *. .:*.*: :.::** * ***: : ...:*******.** **:: *: :* ** .:*****:**. :.:.*:** * ** .:: :*: . : .*** * .**.*:. *: *::: :. :: .. :. *::. * :*:**::. :*:: *.:.* . .::.* * *. :*****: *.. . * : *:::*:**. : . *. ::::::* * .*.:** * * *. .: .* : : :** .:*.*.* * ::** *** .*** *: :*. :: * ** .* :*.**.*:*:: * :. ", "identical_positions": 214, "similar_positions": 242, "identity": "19.74%" }, { "cls_id": "homologset.agr.RGD:621067", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21995-1", "uniprot_id": "EMB_MOUSE", "id": "P21995-1", "name": "Embigin", "aln": "MRSHTGLRALVAPG-YPLLLLCLLAATRPDPAEGDPTDPTFTSLPVREEMMAKYSNLSLKSCNISVTEKSNVSVEENVILEKPSHVELKCVYTATKDLNLMNVTWKKDDEPLETTGDFNTTKMGNTLTSQYRFIVFNSKQLGKYSCVFGE-KELRGTFNIHVPKAHGKKKSLIAYVGDSTVLKCVCQDCLPLNWTWYMGNETAQVPIDAHSNEKYIINGSHANETRLKIKHLLEEDGGSYWCRATFQLGESEEQNELVVLSFLVPLKPFLAILAEVILLVAIILLCEVYTHKKKNDPDAGKEFEQIEQLKSDDSNGIENNVPRYRKTDSADQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88775-1", "uniprot_id": "EMB_RAT", "id": "O88775-1", "name": "Embigin", "aln": "MRSHTGLRALVAPG-CSLLLLYLLAATRPDRAVGDPADSAFTSLPVREEMMAKYANLSLETYNISLTEQTRVS-EQNITLERPSHLELECTFTATEDVMSMNVTWKKDDALLETTDGFNTTKMGDTLYSQYRFTVFNSKQMGKYSCFLG--EELRGTFNIRVPKVHGKNKPLITYVGDSTVLKCECQNCLPLNWTWYMSNGTAQVPIDVHVNDKFDINGSYANETKLKVKHLLEEDGGSYWCRAAFPLGESEEHIKLVVLSFMVPLKPFLAIIAEVILLVAIILLCEVYTQKKKNDPDDGKEFEQIEQLKSDDSNGIENNVPRYRKTDSGDQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PCB8-1", "uniprot_id": "EMB_HUMAN", "id": "Q6PCB8-1", "name": "Embigin", "aln": "MRALPGLLEARARTPRLLLLQCLLAAARPSSADGSAPDSPFTSPPLREEIMAN--NFSLESHNISLTEHSSMPVEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENN--YLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMN-KYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYLVPLKPFLVIVAEVILLVATILLCEKYTQKKKKHSDEGKEFEQIEQLKSDDSNGIENNVPRHRKNESLGQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: .** * *** ****:**. * *...*..*** *:***:**: *:**:: ***:**:: :. *:*: **:**:::* * :*:: *: :*******. **.. : .: *.** :**** ::****:*.***.: :* *****::**: ***:*.**:********.* **:*:******* .* :.:**:..: * *: ***::****:**:.:****** ****** * ******: :*****::*******.*:******** ***** **:***:..* ************************:**.:* .*", "identical_positions": 194, "similar_positions": 84, "identity": "58.43%" }, { "cls_id": "homologset.agr.RGD:621068", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7KTW2-1", "uniprot_id": "Q7KTW2_DROME", "id": "Q7KTW2-1", "name": "", "aln": "----------------------------------------MEMLKYVIS----------------------------DNNYSWWIKLYFAIIFALVLFVAVNLAVGIYNKWDSTPVIIGISSKMTPIDQIPFPTITVCNMNQAKKSKVEHLMPGSIR--------------------YAMLQKTCYKESNFSQYMDTQHRNETFSN---------------FILDVSEKCADLIVSCIFHQQRI-PCTDIFRETFVDEGLCCIFNVLHPYYLYKFKSPY-IRDFTSSDRFADIAVDWDPISGYPQR-----LPSSYYPRPGVGVGTSMGLQIVLNGHVDDYFCS--STNGQGFKILLYNPIDQPRMKESGL---PVMIGHQTSFRIIARNVEATPSIRNIHRTKRQCIFSDEQELLFY-----RYYTRRNCEAECDSMFFLRLCSCI-PYYLPL----IYPNASVCDVFHFECLNRAESQIFDLQSSQC--------------KEFCLTSCHDLIFFPDAFSTPFSQK-------------------DVKAQT-NYLTNFSSEYMRK-NLAVVNFFHTDNYFRSSVRTSYTGPTEYMASTGGIMSLMIGFSVIFLAEIIYIILFVSTLLLILIF------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W250-1", "uniprot_id": "Q9W250_DROME", "id": "Q9W250-1", "name": "", "aln": "-------------------------MEPSPSAGTERQGSSLFLLKSFVRSLR-----QFLNQTSLHGLKFVG-----DSGLSSWERSFFLGSFVTALIITVHLISNIYVKWDSTPVIIGISPQATSILKVPFPAITICNMNQVQRSLVANYREGSNE--------------------SALLKLLCESDSWESSEADEEFSASNFVTNNLKI--------SEFVSNHSQSCERMLLFCRFSAVER-NCSQLFQQILTDEGLCCVFNFQPPEYLYKPFANN-NRNLTNSDGFES--VMWDPESGYPEQ-----LPPKFYPATASGTGITLGFTAVLDAEMGEYYCS--STNGPGFKVYFHNPIEVPKVKEAGL---ISAIGYETNYRIEMVRAEAVPAIRSISRDGRQCLFKNEKELIFY-----RIYTRLNCENECLAAFLYDTCSCI-PFDHPL----IYSNASICSMGDTSCVRRAQRASNRPGWAKC--------------RQQCLPSCFDLNYLASGFSFPLASN-------------------NFQLAN-ALVESFNKSYLSK-NIAVINVYFRESVYYGNTKNAYVGLTEFLSNVGGVMGLFMGFSVISLAEILYFLILKPLAELFVWKRSSHVDSE----------------------------KSLKHNAFGIEKGQSSDNPSFWHSKELYPKGVSISAYENAKSTKGLNYQ-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0KHW3-1", "uniprot_id": "Q0KHW3_DROME", "id": "Q0KHW3-1", "name": "", "aln": "------------MRVPRNRQRAFFASQQKRSRPQHLQITLSTWRRILSRNTD-----EFCRNTTIHGLKYIN-----NSKLRSSDRLFFGIALLVVLSLAIYLIQDAFDKWNTNPVIVGIDPELTSIANEPFPAVTICNLNQALAERVEHFSNDSVE--------------------FAMLQLLCRRKVDVELVKTNDSRWEEFILN------------------ISQPCNSMVIHCRFGADDY-ECARLFHPIVTDEGLCCVFNMLHPRFMYRKRVPYSHRNISLPEGFHA--VNWHAELGYRKRGFQPDGDNPLYPRRAQGTGESLGLSLTLDVQADAYYCS--SSSSIGFKIALHSPNESPNVRETGV---LLAPGMETKLRIDPSKILTEKHLRNVDRRSRRCLFHNELKLRWF-----AHYTQRNCVAECLSGWLIRHCGCV-TFYMPR----LNANDTICPLHKRECVELIRFR-TIIAMESC--------------LDECLPSCFDLSFSAIAYSTRISLD-------------------GFRETPSNGGWNFTDAYVER-SVAVVNMYFKDPTFRANKQTEFIGFSDFLSGVGGLMGLFLGFSFLSIAECVYFALIRPCRTCSEIRQLN----------------------------------QPRVHQMNLKRSPTPGNIRYISAADWFQAELAHQQPNNRQHFNPA--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q708S3-1", "uniprot_id": "ASI4B_DANRE", "id": "Q708S3-1", "name": "Acid-sensing ion channel 4-B", "aln": "------------MPIEFVCKIKFAEGEEAKGASTEGGGTGMLDEGLRRQKEGMADLASFASSSSLHGLARALG----TSERLGFRQTLWGLALLVSLGLFLYQATWSAATYLERPHLAALREETRRELT--FPAITLCNVNRFRFSALT--DADIYH--------------------LANLTGLPPKSRKGHRPSELQYPPPNMLDIFQ---------------RTGHQLEDMLKSCNFSGQNC-SSED-FSVVYTRYGKCYTFNG-------------------------------NKTSPKRVR------------QGGTGNGLEMMLDIQQDEYLPIWRETNETTLEAGIRVQIHSQNEPPYIHQLGF---GVSPGFQTFVSCQEQRLTYLPQPWGN---CRASS---EPVIPGY-----DTYSVSACRLHCESTQVQRECNCR-MVHMP-------GDADICAP---SKIKCVDKALASLQKSTG--------------DSCPCETPCNLTRYGKELSMVKIPS-------------------RGSARYLSRKYQKSEEYIRD-NFLILDIFFEALNYETIEQKKAYDIAGLLGDIGGQMGLFIGASILTILEILDYIYEVAKNKIKQLLKPKKSQKQTNQRNLIQEQIQRTKNLREQNLKAQLTAGAIATVRFEEVKVKAANDVAQPHS--AHPTSVLPNHHN---AQQAVQQDFAC--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q708S4-1", "uniprot_id": "ASI4A_DANRE", "id": "Q708S4-1", "name": "Acid-sensing ion channel 4-A", "aln": "------------MPIEFVCKIKFAEEDEKQKGNQDGDKESLIEESCSPPTK---DLAGFASASSLHGINHIF-----VSGRLGVRQTLWALAFLVSLALFLYQAAKCAISYLEHPHVTALNEEATPEMV--FPAVTICNINRFRFSALT--DADIYH--------------------LANLTGLPPKNKDGHKPTDLEYPAPDMQDIFN---------------RTGHQLEEMLKSCNFSGQNC-SAED-FTVVYTRYGKCYTFNG-------------------------------NKTTSRKTK------------QGGMGNGLEIMLDIQQDDYLPIWKETNETSLEAGIRVQIHSQDEPPYIHQLGF---GVSPGFQTFVSCQEQRLTYLPQPWGN---CRSTS---EQMIPGY-----DTYSISACRLRCETLEVLRECKCR-MVHMP-------GDANICTP---SDIKCVDKALALLQKSSG--------------DTCFCETPCNLTRYGKELSMVKIPS-------------------KGSARYLSRKYDKSEDYIRD-NFLVLDIFFEALNYETIEQKKAYDVAGLLGDIGGQMGLFIGASVLTILEILDYVYEVIKHRLERLLRPQRDDKKQTQQ--------------------QQQASTVATVNLEEMKAKDSSEMSRSHSEGAYANTILPNHHHHHRTHHRVSEDFAC--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9JHS6-1", "uniprot_id": "ASIC4_RAT", "id": "Q9JHS6-1", "name": "Acid-sensing ion channel 4", "aln": "------------MPIEIVCKIKFAEEDAKPKEKEAGDEQSLLGAAQGPAAPR--DLATFASTSTLHGLGRAC-----GPGPHGLRRTLWVLALLTSLAAFLYQAASLARGYLTRPHLVAMDPAAPAPVAG-FPAVTLCNINRFRHSALS--DADIFH--------------------LANLTGLPPKDRDGHRAAGLRYPEPDMVDILN---------------RTGHQLADMLKSCNFSGHHC-SASN-FSVVYTRYGKCYTFNA-------------------------------DPQSSLPSR------------AGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLGF---GVSPGFQTFVSCQKQRLTYLPQPWGN---CRAESKLREPELQGY-----SAYSVSACRLRCEKEAVLQRCHCR-MVHMP-------GNETICPPN--IYIECADHTLDSLGGGSE--------------GPCFCPTPCNLTRYGKEISMVKIPN-------------------RGSARYLARKYNRNETYIRE-NFLVLDVFFEALTSEAMEQRAAYGLSALLGDLGGQMGLFIGASILTLLEILDYIYEVSWDRLKRVWRRPKTPLR-------------------------TSTGGISTLGLQELKEQ-SPCPNRGRAEGGGASNLLPNHHHPHGPPGSLFEDFAC--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TNS7-1", "uniprot_id": "ASIC4_MOUSE", "id": "Q7TNS7-1", "name": "Acid-sensing ion channel 4", "aln": "------------MPIEIVCKIKFAEEDAKPKEKEAGDEQSLLGAAQGPAAPR--DLATFASTSTLHGLGRAC-----GPGPHGLRRTLWALALLTSLAAFLYQAASLARGYLTRPHLVAMDPAAPAPVAG-FPAVTLCNINRFRHSALS--DADIFH--------------------LANLTGLPPKDRDGHRAAGLRYPEPDMVDILN---------------RTGHQLADMLKSCNFSGHHC-SASN-FSVVYTRYGKCYTFNA-------------------------------DPQSSLPSR------------AGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLGF---GVSPGFQTFVSCQEQRLTYLPQPWGN---CRAESELREPELQGY-----SAYSVSACRLRCEKEAVLQRCHCR-MVHMP-------GNETICPPN--IYIECADHTLDSLGGGSE--------------GPCFCPTPCNLTRYGKEISMVKIPN-------------------RGSARYLARKYNRNETYIRE-NFLVLDVFFEALTSEAMEQQAAYGLSALLGDLGGQMGLFIGASILTLLEILDYIYEVSWDRLKRVWRRPKTPLR-------------------------TSTGGISTLGLQELKEQ-SPCPSRGRAEGGGASSLLPNHHHPHGPPGSLFEDFAC--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96FT7-4", "uniprot_id": "ASIC4_HUMAN", "id": "Q96FT7-4", "name": "Acid-sensing ion channel 4", "aln": "------------MPIEIVCKIKFAEEDAKPKEKEAGDEQSLLGAVAPGAAPR--DLATFASTSTLHGLGRAC-----GPGPHGLRRTLWALALLTSLAAFLYQAAGLARGYLTRPHLVAMDPAAPAPVAG-FPAVTLCNINRFRHSALS--DADIFH--------------------LANLTGLPPKDRDGHRAAGLRYPEPDMVDILN---------------RTGHQLADMLKSCNFSGHHC-SASN-FSVVYTRYGKCYTFNA-------------------------------DPRSSLPSR------------AGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLGF---GVSPGFQTFVSCQEQRLTYLPQPWGN---CRAESELREPELQGY-----SAYSVSACRLRCEKEAVLQRCHCR-MVHMP-------GNETICPPN--IYIECADHTLDSLGGGPE--------------GPCFCPTPCNLTRYGKEISMVRIPN-------------------RGSARYLARKYNRNETYIRE-NFLVLDVFFEALTSEAMEQRAAYGLSALLGDLGGQMGLFIGASILTLLEILDYIYEVSWDRLKRVWRRPKTPLR-------------------------TSTGGISTLGLQELKEQ-SPCPSRGRVEGGGVSSLLPNHHHPHGPPGGLFEDFAC--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86LG1-1", "uniprot_id": "PPK28_DROME", "id": "Q86LG1-1", "name": "Pickpocket protein 28", "aln": "-----------MRTLTESRRRQSGSSGCKKDSESDDDENTICSRAAIKRSVVY-----YLKNSTLHGLKYIA-----EESITIPERIFFGLAFVLVVILSVFFISNVYVKWSASPIIISTSAKQKLTSNMPFPAITICNLNQALLSKVDRIGRTSTN--------------------FSLLMGLCDQGGDTTISYIGTWKYFKAILVD-----------------VAQPCEKMLLYCSFGSREE-DCSWLFTSILTDDGLCCNFNALHPSYLIRNYSDDVRLETAHPN-TRYELIDWTPEKGYARN-----LPEFYFPRTSGGTGIRMGLTVVLNASIAEYYCT--KSMSVGFKVLVHNPAELPKVSNYGF---VVTAGREARIPIEPVYEDALPTIRSIKKSVRRCLFSDENDLAYY-----RTYSRKNCELECEAKLLLRECSCV-LYYLPR----IDPLARVCGPNDNQCTDRVQTEIESSLTNLS--------------CENCWPGCFELTYRATLSTASIVSDP------------------RFQAGENLPEYIFHGPYSNASEISILHFYYMTNIFRSTTKSEMFGFTEFLSNTGGLLGLFMGFSIFSVIEIFFYITVRPYCASRTLRQRHKRRLEQLSWLTPIR---------------MPVRRALRRNRGGLLRNPPPPAYSDLQKFRGKLDKPETCKRKLWRTLQVRPVVDRADEELPTYPYLD---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JV41-1", "uniprot_id": "A8JV41_DROME", "id": "A8JV41-1", "name": "", "aln": "--------------------MPQEKRHPPESRTQRFLETLVIFRRSLIYQTK-----EFFQNSTLHGVRYIA-----ESGRPIGEKFMWFCFTSIGAVTALVIIMSLWEKFQTNPTITGLDTDFHNQNVV-FPTTVVCPEAAFDHDKTYEKVYNTLANY-------DEAQAQMYTPFLRILTSLNFENVRDAKVLSQSIPQNLLDAHTIR----------EWAFEGHIDCKNVFVSCKYRDEDI-PCCDHFEPIYTEHGFCYAFNSR---------------------------FKSTPTEDVKTG----------APHDLYETDKKWALFFIPNSTSRIFIFSNEEYFGSDFNAQIDWSEPQ-----------------LVEVRISKKNTYTTDDARQLSIGQRKCIFSDEVKLNYFP----DAYTFSSCMKQCRMNKAIKLCKCNPPFYKPI----RELSCVINIFTNLIAYILLLYLTPKANVPMC--------------SIKDFDCLDEFKSNITNIKDCLQCEL------------------SCSKTVFNIDKLIKMSDRPE-SLGVLVEFLTWPIIR-YKREVLFGWVDLLVSFGGIASLFLGFSLLSGVEIIYYFTLRACCMVYKNRQELYEIEEKIRQEPPPKIDLKLSLKSHNPRIGDTPTSAVLKVKPAEESAGPNPLGGYQRKHEKDYSLNTKNYYKTPKVVPDYGYTSKTKNSWTTYDHSQYMP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8DYP1-1", "uniprot_id": "A8DYP1_DROME", "id": "A8DYP1-1", "name": "", "aln": "-----------------------------------------MWRKSVMNFRG-----------------FIR-------SFVENKGLLWIFVIGISGWSTVSILVLLKTRYETDSTTIGVSTAYSRWINT-FPSIGICLTKSRAFNEFKAMMREYFQED-------FAFSFTRMIYEYAFLNPNNIFTKEPTKNTSYPYNFNILDIRRK---------------MFPTNCTECFKEIYFRGELVTDCEEIFKFHVTEMGYCFLANN---------------------------LLDYDSIEEMPLR------------YSSLDNNRSLRLYMR-------------SSVMYKYEMYVNSPEDLPFFNSLTY---TISTD-PTTYAFNVEEIHNHEGVIDEPISQRKCKFPSESSIEGF------PYSFSACMSIIRSEFEMKTCDCS--LFNPK----DRNESLYCGLQHADCLIKEGFATRVKEYVGS--------------STVCLPSCVEQQISLVGVITEN------------------------------------GTLYNN-NTQITEIQIASPPTVRYERKVTQTKLDLIVGIGSVAGLFFGASLLNLLEIISYFIKKLKTMIFG--------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9Y5-1", "uniprot_id": "Q9V9Y5_DROME", "id": "Q9V9Y5-1", "name": "", "aln": "MPVEMESLDQKPFRLAVGRAAWWIPNPGRVARYPPIRTLAPNHLPGTSAEDTRKLSFAAALKDLLQNLSFHCYSKLVESGRRIQERFFWFVFHITALTVLIAFLWGTYTK-EQEALVTTMYHPMYPIWKVEFPAISVCSLNRISQRAAWQYAHNLSGKD-------PKQRNASHFYDQLKAFMYMYYDPSDLMDIDNALRFQSFLDRFDTAKEELFFNTRNRMSALTPNCSDMFVSCRIAGRLF-DCMDKFETTLTSHGFCCTFNYDG---------------------------RYVNKRDFRQR--------------YFGPDMGLVLTLKTDPSDNFYKINGHNGYPDPFSGGVAERVAET--------------GFNTLLPVRAKIFETLPEARSMSPSVRKCLFENEMPWIFA-----RHYTFSKCISACRAQSVVSLCECV-PFSLPHRYIDGSEKRIYCTLQHLACLKRYEFKWLNVITSRENVTGLEHELQDALYCPLCLASCTETRYSVRGAMTLGLPTPSQIKGPARSNPGPRANNSYGPASSSGSAKGPVHSSSAPAELAVVRIYFAETHIQYFRQIIKSAWYETFSTIGNICGIIAGFSLIGICELLFFLAKQLWQACRAELRAELAHIH----------------------------VQIRNAQVAEPEAERPMKLFILP-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAJ7-1", "uniprot_id": "Q9VAJ7_DROME", "id": "Q9VAJ7-1", "name": "", "aln": "--------MLYPLELPRARRPLYRDYGGKSGLIQTQRDARKNSRLGKLWHFMLPYLKDYAAESSVHGIRYLADP---KMRNYLNIRVIWLLILLTTSIGAIVVYVDLNELYQTVRIQTTIKNTMLPIFRIPFPSIGLCPRNRLNWKILETEAVDHFLG--------ANVSAAQKDLFVKFFTAAGDPHLSRLNEMSNFFGNKTLTDELHMLDHLDLR---EVYKFIQFRCQDLFHTCRWRGNPV-NCCEVIEYQFTEAGLCFVFNTEISPASR---------------------QKAREDKYYPLR------------TPHYGEGSGLDLFLRLNRSFIR-------PGKRGINVMIKQPQQWSDVVR------HVPHEAHTRISITPRFTVTDERTRTVTPEIRRCIFGDEVDNPHYKNFPDFEYWVGNCRSRCHQEHVLNLCKCSPSIFFPIS---DKDNFTACKASDFKCLYDNRFTFSIERHPEE---------------DDFVKNPFKESMICDCFTSCSQLVF---------------------DRVFTTTTLDNNETDTEAGTMRLDIFYQSGWFIQYQTNMRFTFVELLASFGGIIGLFLGASLLSAFELAYYFSIGLYLYIHGKRKLRKPEPG------------------------------VLTIQFGQRKITPIKF------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O61365-1", "uniprot_id": "NACH_DROME", "id": "O61365-1", "name": "Sodium channel protein Nach", "aln": "-------------------------MGHQEELKPEQVDLKVTPFVGYLRRTWS----DFCATSSIHGLKYTR-----DEDTNKIVHLVWLLISVVMFICAVVMARTFYMDYRSSPTRMNVESDNTPVNRLYFPPVTICPDVLFNMQKSEAFLNTLRLPK-------G-AELRGILRKLHIFYGFMLDDERYSAEDIEQMEALLFLNNLTIP---------EFVEHLRWNCDEILYRCRFNGEIM-DCSKIFQLSKTFFGHCCSFNLRQKGWVNN------------------KLNNLESFKVFHLN---------SLNFTAQRAIGGLRYGLSVVVRYKDDNYDPLQSYSYGVKLLIQEADAFPSAHSAAK---FIAFNSETFAAVRPQETFCSSAVKALIIEERNCVFQNEFPMRYFS-----DYVYPNCELNCRVTNMVKFCGCHTYFFDFN-----RTSDRICTFRDIPCLVDNFANIITRKKSTQ---------------CYCPLTCEHIDYDVQLTNFPLELN-------------------------MPVADKFYSGLAKN--DGVLHVFINSFSYRRLRRDLLSNMVTLVSNLGSAFSLFVGMSMLSVVEIIYYFSVILRKNYKLECETRSQMLHK--------------------------KPKFAWPKANDTHSKEQKSVFIIHKS-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8MLR6-1", "uniprot_id": "Q8MLR6_DROME", "id": "Q8MLR6-1", "name": "", "aln": "----------------MSNERVLLWIRGAAARILRGLLALLWLILAGCGRLFGRLRDVVAQAGAETGLLALS--LCVNRSIHLLERLFWLAVVVSSVIAALVLSRLQLERYFSSPTVISVDRDYRGWNGS-LPAVTLCYYDHIDSFKANEYIQEMWN---------VSIIDEDYFYFMDFLYAVVNATAGNYAELAKFAEDERFDQIDLY--------------EMIQRVDRPFEQVISSFDAG--FQVHVQRVMTERGACYAINS--------------------------------PMSTVLSG---------------QPVAYELMPQPLSCQYGKQQCYIRMDLYESTGVLDVHSPFEVSATEANIV---ALHKSDEITASFKVLETVASKNLRQLSVAQRKCVFNNEETSNLK------IYSKSLCLARCRAVMALEMCNCV-PFFYPY------VDGPSCNPAGFECLLDFKWPIWALHICKCP------------------STCTEIEYTMQTVKKSSWGVK------------------------------NNEEVASSETATSSFRWDLIPPKVRMRRDVVYSFEDLVVSFGGVLALFVGVSVMGLVEMVHVLVNNLLLDVFTLLRLMLGRLRR------------------------CWRRDDHMREANHHHHANAHAHARLHDFNERLSLAATAELPPFDYVN----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VL88-1", "uniprot_id": "Q9VL88_DROME", "id": "Q9VL88-1", "name": "", "aln": "---------------------------------------MARVEESYYRRLFR----EFLRQSYINGLHPFLY-----HTPVRYAKAIWLAFLTAIMIYTHIVIADLILEYLVQPTEIHMAPDLVHVANSPFPAVGVCTSNKINGRLLRSYAEKLFHHQGNSSLQAVALDLDDMANRLLVLAQFYLNPLESDHERWNATELDRLHRLLVAYHNGAGYSVRDILRDLSPGCGDLVIRGIVFGLPV-NASQLFLKRPTSSNVCCIFNYRRPSYS--------------------QFLTKRAEEDSEMR---------AVPMVVFESNSILNSVQFVLQDTPKEDITNTFHSNSAFQLIIFPQEDYATIQSTTLGEVLVDHYSIVEIPIQPMFFSSGDGVRGVPPHIRRCYYPEEGMRLLN----QSYYSLDECLLVCRMKSMIDHCGCVSPPLTGS-----SMDLDYCMLPDLPCLMRWKSIWYGYSDFAYLQN--KEENLVQRQCEHCLPTCNGVSMSITTNVAPLRRTYN----------------------SSGYFTGLLKGLTNERPLAIIKLFFKLRFAQATKSQMVSSWVVLLNRFGGILSLMYGFSIVSYIEILYYLTGKGFVYIYRSFLLDKEPIN-----------------------------HNYSLYWRELRSNLPRQEQLRK-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJI4-1", "uniprot_id": "Q9VJI4_DROME", "id": "Q9VJI4-1", "name": "", "aln": "--------------------------------------------MGYWSETR-------------------------AWLFRDPAKLIRYLVLFACCIVVIVQLYECFAKLYNPPISTHSYYSLN--ETIEMPSVTICREPPYKEEVLTRLSGGACP--------------------HPKYATCWMKYPFGEISLDEFFEN------------------------STHDSGDTFVFYGLNEDKN--NVVMNSSLHFYMGRCYTLRP----------------------------------KESAKR-----------------VSKAVGYSIMLEHSMLTTSVSDVDTGSVGWHVFIHDKKENFTEINMKG---------SGRVEYVFVGVNEEIEIKLQTQYFSNVQTREEACSDDE------NYSDLKCGEQCIWQDLADNMQCSGPWMHEIA-----SEPCNDSLSMRKLISDYKDVYENEDDFDC----------------DCVQPCQSRIYTTFIQ--------------------------------------NRKAFNQPEPRTQIYIYYTTKLISMIEERPSYDTTQFIADVGGSLGFLLGLSVLGLIGILEHMMLFFCGGFIKRMQQKEQ----------------------------------AKLEANSEDGQSQTSDETIDVEIAYKKKEKQPKY-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. :* . . * . . * * * * . *. .:: * *.. ", "identical_positions": 10, "similar_positions": 14, "identity": "1.36%" }, { "cls_id": "homologset.agr.RGD:621069", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54963-1", "uniprot_id": "REST_RAT", "id": "O54963-1", "name": "RE1-silencing transcription factor", "aln": "MATQVMGQSSGGGSLFNNSGNMGMALPNDMYDLHDLSKAELAAPQLIMLANVALTGEVNGSCCDYLVGEERQMAELMPVGDNHFSDSE-GEGLEESAELKGDPSGLDNMELRSLELSVVEPQPVFEASAAPEVYS--SNKDPAPEAPVAEDK--------CKNLKAKPFRCKPCQYEAESEEQFVHHIRVHSAKKFFVEESAEK----QAKARESGASPSEEGE--FSKGPIRCDRCGYNTNRYDHYTAHLKHHLRAGDNERVYKCIICTYTTVSEYHWRKHLRNHFPRKVYTCSKCNYFSTEKNNYVQHVRTHTGERPYKCELCPYSSSQKTHLTRHMRTHSGEKPFKCDQCNYVASNQHEVTRHARQVHNGPKPLNCPHCDYKTADRSNFKKHVELHVNPRQFNCPVCDYAASKKCNLQYHFKSKHPTCPSKTMDVSKVKLKKTKRREADLHRDAAAAATEQTDTEQAKTKGVDASARRSERPVKGVGKDVPKEKKPCSNASVVQVTTRTRKS--AVETKAAEGKHTDGQTGNNAEKSSKAKKSKRKMDAEAHPSVEPVT-EGPVTKKKK-TESKPK-TSGEVPKGS-RVEDRKADKQQSASIKKGGKKTALKTKTAKKGSKLAPKWVGHTEPSS-EMAQGGESPVPALTQAVVTPSGSTQTELS----SPMDIAQTEPAQMDVSQTGPPQVQRPLPVEPAQLE-----PSPPQEPPQVEPPACVEPP-----------------PPVEPPCPMEPAEMEPSPPMEPSQVEPPPHLEPPLPMELPQVE------LPPVEDCQKELP-PVEHAQTKVAQTGPTQVGAVQEEPLFCLRATSSQANQKVISPKDRAKEKLSVLSEMARQEQVLIEVGLVPVRDSQLLKASKSAPDLPAPPSPLPKGHLRREETPKDQEMFSDGEGNKVSPLEKGGTEEAGESRAELAA-PMESTSALSSEQSSNAPDGETLHSECQADSTAVCEMEVDTEQKT--DRVPLKDSAVEPVSPLNP---RVDPEAAAPAVVASPPITLAE--SQEIDEDEGIHSHDG-SDLSDNMSEGSDDSGLHGARPAPQEATSKSGKEGLAVKVTEGEFVCIFCDRSFRKEKDYSKHLNRHLVNVYFLEEAAEEQE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIG1-1", "uniprot_id": "REST_MOUSE", "id": "Q8VIG1-1", "name": "RE1-silencing transcription factor", "aln": "MATQVMGQSSGGGSLFNNSANMGMALTNDMYDLHELSKAELAAPQLIMLANVALTGEASGSCCDYLVGEERQMAELMPVGDNHFSESE-GEGLEESADLKG----LENMELGSLELSAVEPQPVFEASAAPEIYS--ANKDPAPETPVAEDK--------CRSSKAKPFRCKPCQYEAESEEQFVHHIRIHSAKKFFVEESAEK----QAKAWESGSSPAEEGE--FSKGPIRCDRCGYNTNRYDHYMAHLKHHLRAGENERIYKCIICTYTTVSEYHWRKHLRNHFPRKVYTCSKCNYFSDRKNNYVQHVRTHTGERPYKCELCPYSSSQKTHLTRHMRTHSGEKPFKCDQCNYVASNQHEVTRHARQVHNGPKPLNCPHCDYKTADRSNFKKHVELHVNPRQFNCPVCDYAASKKCNLQYHFKSKHPTCPSKTMDVSKVKLKKTKKREADLLNN--AVSNEKMENEQTKTKG-DVSGKKNEKPVKAVGKDASKEKKPGSSVSVVQVTTRTRKSAVAAETKAAEVKHTDGQTGNNPEKPCKAKKNKRKKDAEAHPSEEPVN-EGPVTKKKKKSECKSK-IGTNVPKGGGRAEERPGVKKQSASLKKGTKKTPPKTKTSKKGGKLAPKGMGQTEPSSGALAQVGVSPDPALIQAEVTGSGSSQTELP----SPMDIAKSEPAQMEVSLTGPP------PVEPAQME-----PSPAK-PPQVEAPTYPQPPQRGPAPPTGPAPPTGPAPPTEPAPPTGLAEMEPSP-TEPSQKEPPPSMEPPCPEELPQAE------PPPMEDCQKELPSPVEPAQIEVAQTAPTQV---QEEPPPVSEPPRVKPTKRSSLRKDRAEKELSLLSEMARQEQVLMGVGLVPVRDSKLLKGNKSAQDPPAPPSPSPKGNSR-EETPKDQEMVSDGEGTIVFPLKKGGPEEAGESPAELAA-LKESARVSSSEQNSAMPEGGASHSKCQTGSSGLCD--VDTEQKT--DTVPMKDSAAEPVSPPTP---TVDRDAGSPAVVASPPITLAENESQEIDEDEGIHSHDG-SDLSDNMSEGSDDSGLHGARPTPPEATSKNGKAGLAGKVTEGEFVCIFCDRSFRKEKDYSKHLNRHLVNVYFLEEAAEEQEEQEEREEQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13127-1", "uniprot_id": "REST_HUMAN", "id": "Q13127-1", "name": "RE1-silencing transcription factor", "aln": "MATQVMGQSSGGGGLFTSSGNIGMALPNDMYDLHDLSKAELAAPQLIMLANVALTGEVNGSCCDYLVGEERQMAELMPVGDNNFSDSEEGEGLEESADIKGEPHGLENMELRSLELSVVEPQPVFEASGAPDIYS--SNKDLPPETPGAEDK--------GKSSKTKPFRCKPCQYEAESEEQFVHHIRVHSAKKFFVEESAEK----QAKARESGSSTAEEGD--FSKGPIRCDRCGYNTNRYDHYTAHLKHHTRAGDNERVYKCIICTYTTVSEYHWRKHLRNHFPRKVYTCGKCNYFSDRKNNYVQHVRTHTGERPYKCELCPYSSSQKTHLTRHMRTHSGEKPFKCDQCSYVASNQHEVTRHARQVHNGPKPLNCPHCDYKTADRSNFKKHVELHVNPRQFNCPVCDYAASKKCNLQYHFKSKHPTCPNKTMDVSKVKLKKTKKREADLPDN---ITNEKTEIEQTKIKG-DVAGKKNEKSVKAEKRDVSKEKKPSNNVSVIQVTTRTRKS-------VTEVKEMDVHTGSNSEKFSKTKKSKRKLEVDSHSLHGPVNDEESSTKKKKKVESKSKNNSQEVPKGDSKVEEN---KKQNTCMKKSTKKKTLKNKSSKKSSKPPQKEPVEKGSAQMDPPQMGPAPTEAVQKGPVQVEPPPPMEHAQMEGAQIRPAPDEPVQMEVVQEGPAQKELLPPVEPAQMVGAQIVLAHMELPPPMETAQTEVAQMGPAPMEPAQMEVAQVESAPMQVVQKEPVQMELSPPMEVVQKEP-VQIELSPPMEVVQKEPVKIELSPPIEVVQKEPVQMELSPPMGVVQKEPAQR----EPPPPREPPLHMEPISKKPPLRKDKKEKSNMQSERARKEQVLIEVGLVPVKDSWLLKESVSTEDLSPPSPPLPKENLR-EEASGDQKLLNTGEGNKEAPLQKVGAEEADESLPGLAANINESTHISSSGQNLNTPEGETLNGKHQTDS-IVCEMKMDTDQNTRENLTGINSTVEEPVSPMLPPSAVEEREAVSKTALASPPATMAANESQEIDEDEGIHSHEG-SDLSDNMSEGSDDSGLHGARPVPQESSRKNAKEALAVKAAKGDFVCIFCDRSFRKGKDYSKHLNRHLVNVYYLEEAAQGQE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKA2-1", "uniprot_id": "A0A0R4IKA2_DANRE", "id": "A0A0R4IKA2-1", "name": "", "aln": "MSQPVFPTASG------------IFLP-------DLHHDEVSAPQLVMLANVVVSAEAS--ASEYST-EGKQMMELQTVACSSYSDSEEDDDAVVRYSMDT------SEDLYTQQASHIQPEPVLEEIEIVRVGRPPNQTESTENAASAEQKRTTLAILESSKKKKKPFFCKPCQYQGENEQEFIVHIRTHGAKKMLVVNGGDSDEDLSADAGPQTSVPNAESAESNSKGVIRCERCGYNTNRFDHYMAHLKHHTKEGEDQRVFKCTICAYTTISQYHWKKHLRNHFPSKLFTCSQCSYFSDRKNNYIQHIRTHTGERPFQCIYCEYSSSQKTHLTRHMRTHSGERPFKCDNCSYLAANQHEVTRHARQVHNGPKPLSCPYCQYKTADRSNFKKHVELHVNPRQFLCPVCKYAASKKCNLQYHIKSRHPGCKDISMDVSKVRLRVKRSDGDDASPN-------KLTAEQAKIME----------ELEDAGPINLSIKKPSKLNAVVETEKSSKKN----------------MDGKANQPQPNEKKSLSKNEPK----------EKTAKKLKGKTAVKDT---EETQTEDTRVNNKKETKKAEKSAEKALKSRQKKEKPVKDSS---------------------------VQQ---QSDDCEQTQHT-------------PQQNETQENRPE-------------------------------------------------------------------------------KENRSLTEIDNAKDCGKVQ--------TKKPCKKQTKTLKVCGETQNVEEEEIMR----QKAGKRKADNPAEPKQRIKRTKKKDSGK-PTTSEANQTNPEVMES-----ESSEANNASKPDDSIDESQNP-PVAESR----------------------PDVEPQSVPDCPIEKAPAVEEVQRPLEVEISTAAPDAPEVDSGNEMPS-------------------PTDSDGAPGFTPTLP----------------------LQHKPADAEDDEGIHSNDGGSDISDSASEGSYDSGLMAGAEKLPETPTEERDASAARLLSH---TCIFCDRSFALEMDYRKHLNRHLVNVYYLEGAAQGGK---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *: :** : *. :* : *::****:*****.::.*.. ..:* . * :** ** .*. . :*:** .:. .:. . :* : : * ::*:**:* : :.: . ::. **:* . * *** ******:.*.*::*: *** *.***::* :..:. .*.* . : . *. *** ***:********:*** ****** : *:::*::** **:***:*:***:******** *::**.:*.*** .****:**:********::* * *******************:*****:*.*:*:*******************.**:*:********************** ****.************:**:** * . :******:*: .: * : : **:* :: . *** . :*::. . ::*. *. : : **. * : . * . .* * * . :. . . :.::. *: . . :*. *. * *. *... : : . : . * * :. * * * . : : : . : :*: .: : . :. .: :. . : ** : : :: ..* : . . . . * * . * . .:.. :. *. * . . *:. .. : * .. .:* * . : ::******::* **:**. **** **** .. *:. :. . . * :. .******** ** ***********:** **: : ", "identical_positions": 313, "similar_positions": 232, "identity": "27.36%" }, { "cls_id": "homologset.agr.RGD:621070", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PSL8-1", "uniprot_id": "E9PSL8_RAT", "id": "E9PSL8-1", "name": "Kinesin-like protein", "aln": "MVKQTIQIFARVKPSVRKQQQGIYSIDEDEKLASSLEIVLPRDLADGFVNNKRESYKFKFQRIFDQEAKQEIIFEIIAKPVAESTLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASKLEDLPKVTILEDPDQNIHLKNLSLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTVHLSSKEPGSATVRHAKLHLVDLAGSERVSKTGVGGLLLTEAKYINLSLHYLEQVIIALSEKHRTHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNIDESISTCRFAQRVALIKNEAILNEEIDPRLMIVRLQKEIADLKAELAMVTGEQRTEALTEAELLQLEKLIASFVEDQDPESRLEVGADLRKIHYCFHHFKKLLNDKKTLEN-TDSSESTTQQACQEPVKDEEYTKLRSLLKQRDNEINILVNMLKKEKKKTQDALQYSSTEKSEARPPPNSPFIAGSP-AGQRTSFSSSLSQTQDLSVYRHRSSLLHKKTGMREEMSLGRQEAFEIFKRDHADSVTIEDNKQVLKQRFSEAKALGESINEARSKIGQLKEAISQRHLQQVALGIAESMAPPSTPDPQEQKLRAQLEEEKSRYKTTFMRLKALKVEIEHLQLLMDKAKLKLQKEFEAWWAEEASSLQVNSPATNLQDAAKPFPQQDQ-----TQLLSKKS--SQGLEVEN-GAGKLDVCGRNARRILPSPCPSPHSQEPSGSSIQLQD----RP-SSIPLTGDRQTDSDILAFIKARQSILQKKCLGSN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PX57-1", "uniprot_id": "E9PX57_MOUSE", "id": "E9PX57-1", "name": "Kinesin-like protein", "aln": "MVKQTIQIFARVKPTVRKQQQGIYSIDEDEKLTHSLEIVLPRDLADGFVNNKRESYKFKFQRIFDQEAKQEIIFEIIAKPVAESTLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASKLEDLPKVTILEDPDQNIHLKNLSLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTVHLSSKEPGSATVRHAKLHLVDLAGSERVSKTGVGGLLLTEAKYINLSLHYLEQVIIALSEKHRTHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNIDESISTCRFAQRVALIKNEAILNEEIDPRLMIVRLQKEIEDLKAELAMATGEQRTEALTEAELLQLEKLIASYLEDQDPESRLEVGADMRKIHHCFHHFKKLLNDKKTLEN-TVSSES-TRQACQEPLRDEEYTKLLGLLKQRDNEINILVNMLKKEKKKTQDALQNSSLEKSDTRPPQNSPFIAGSP-AVPRTPFSSAPSHTQDLSICRHRSSLLHKKTGMREEMSLGRQEAFEIFKRDHADSVTIEDNKQVLKQRFSEAKALGESINEARSKIGQLKDAINQRHLQQVALGISENTVPASTPDPQEEKLRAQLEEEKGRYKTAFMHLKALKVEIEHLQLLMDKAKVKLQKEFEAWWAEEATSLQVNSPATNLQDAVKPFPQQDQ-----AQLLSKKS--SRDLEVEN-GAGRLEVCDRNARRILPSPCPNQQSQEPSGSRVLVQD----RPLSSIPLTGDSQTDSDILAFIKARQSILQKKCLGSN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZMV9-1", "uniprot_id": "KIF6_HUMAN", "id": "Q6ZMV9-1", "name": "Kinesin-like protein KIF6", "aln": "MVKQTIQIFARVKPPVRKHQQGIYSIDEDEKLIPSLEIILPRDLADGFVNNKRESYKFKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIPRTLSYIFEQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILEDPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEPGSATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRSHIPYRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEINPRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMRKVHHCFHHLKKLLNDKKILENNTVSSES-KDQDCQEPLKEEEYRKLRDILKQRDNEINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQDFSILGKRSSLLHKKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALGESINEARSKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRRYKTMFTRLKALKVEIEHLQLLMDKAKVKLQKEFEVWWAEEATNLQVNSPAVNSLDHTKPFLQTSDSQHEWSQLLSNKS--SGGWEVQDQGTGRFDVCDVNARKILPSPCPSPHSQKQSSTSTPLEDSIPKRPVSSIPLTGDSQTDSDIIAFIKARQSILQKQCLGSN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HN43-1", "uniprot_id": "A0AC58HN43_DANRE", "id": "A0AC58HN43-1", "name": "Kinesin-like protein", "aln": "MVKQTIEIFARVKPTKKPTSEYFADCDEQG---GSLLFLVPRDAADGFINNKRENYKFRFQKVFDQTASQEEVFENIAKPVADNVLAGYNGTIFAYGQTGSGKTFTITGGAEHYNDRGIIPRTLSYLYRYFSMNNTMIYTTHISYLEIYNESGYDLLNPQHEASRLEDLPRVTIMEDPDQNIHLKNLSLLQSANEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLCSKELGSARVRCSKLHLVDLAGSERVGKTGVGGQILTEAKYINLSLHYLEQVIIALSEKDRSHIPYRNSMMTSVLRDSLGGNCMTTMIATVSVEKKNIGESLSTCRFAQRVALIKNEALLNEELDPALLIVHLKKENQSLKEQLALMTGEQRSDKLTQEEIQQLEGLVNVYLEDPDCEVTLDLGPDMRKIQFCFSLLKARVREKPCAGS-SIPLTG--MLDGKDRRSHEDVQKLEEMLAHRDNEISILVNMLKREKKKLQDVT--SQMTKPQNKNESPTTLEAAES---AKYDSSNGDIHAQHLMTGKRVP-----------ELSAGQQEVFEVFLRDHKEHLSIEDKRAVLQQRFVEAKALGEQVNQIRTRVNYLKGELKNRRKQMAVQGLTGNQT-ESELDPFEEKILTQIEEEKKNYKITSGCLKDLKTEIEHLQLLLEKSKVKIQSDFENWWTQEGARLQGHS-GENTGNNRRGISPLSHMLTRKNNLKDDESDLHEGRQGEIRDKRSLPSCDFSSTPFLLTGDKKTDADIEAFIRARHNLLNSTDDQICFPEWLESGQQRHCRWPLEIYQFICVCGDSGHNY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*******. : .: : . **: ** :::*** ****:*****.***:**::*** *.** :** ****** ..***************************:*.***********::. :. :.: **************.*****:*:**** *****:***:************:* *::.**********************************:**.*** *** ** :*************.****** :************************.*:****************************:*:**:*:.**:****************:****::* *:* :*:** .** :**: *****:: **: *: *** *: ::** * : *::*.*:**::.** :* :.:* . : . . :: .*: ** :* :*****.*******:**** *:. : : : : ..: ... : *.. ::*.: : . *:* * **.**:* *** : ::*:*:: :*:*** *******.:*: *:::. ** :.:*: * .. *:: . . * *:*: :*:**** .** ** **.********::*:*:*:*.:** **::*.: ** :* . * : : : .. :* ..:* . : : . : *. .: :* : . .:: : : .:* : : . :: * * * * ", "identical_positions": 407, "similar_positions": 192, "identity": "49.76%" }, { "cls_id": "homologset.agr.RGD:621071", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7M6Z5-1", "uniprot_id": "KIF27_RAT", "id": "Q7M6Z5-1", "name": "Kinesin-like protein KIF27", "aln": "MEEIPIKVAVRIRPLLCKEVLHN------------------------------------------------------------------------HQVCVRDIPKTQ--------------------QIIIGRDRVFTFDFVFGKNSTQDEVYSTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGG-GHVASVVDGQKGIIPRAIQEIFQSISGNPNIDFKIKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECQVDSVEDVMGLLQVGNAARHTGTTQMNEHSSRSHAIFTISVCQVGKSAEATEDGEWCSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDP---RRKSSHVPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPTLNFSPQADRMDEMEFEIKLLREALQSHQASISQTSQTASENVPDQNRIHSLEEQIAQLQEECLGYQDCIEQAFAFLVDLKDAVRLNQKQQHKLQQWFSRTQEVRKAVLTPLPGNQSIGNLEEGPQHVTVLQLKRELKKYQCALAADQVVFTQKELELEELRRQMQLMAQESKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELAKRSSSMPTSTKESCGDGPDARAPEKRPHTAPFDSHWGHYVYIPSRQDFKKVCSSSPVYSLDQVFAGFRTRSQMLMGHLEDQDEVLHCQFSDNSDDEDSEGQEKPRVRSRSHSWVKKPGSVCSLVEMSDTQAECQRSYLGNGDLKMESLQESQELNLQKLRTSELILNKAKQKMRELTINIRMKEDLIKELIKTGDNAKSVSRQYSLKVTKLEHEAEQAKVELTETRKQLQELEGKDLSDVALKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRASELEQNVDHLKYQKVQLQRRLREESEKKKQLDAEVKRDQQKLKELQLNAGQGEGLHPKAEDTDAFNLNRRKGPFRSVDQLQKLDEQRKWLDEEVEKVLSQRQELEMLEEELKKREAIVSKKEALLQEKSHLENKKLRSSQALSTDSLKISARLNLLDQELSEKSLLLENSP-TEEKVKISEQVQALQREREQLQRQRNSVDEKLRHGRVLSPKEEHLLFQLEEGIEALEAAIEFKNESIQNRQSSLKSSFQNLSQSESNVLEKLVCLNIAEIRAILFKYFNKVINLREAERKQQLQNKEMKMKVLERDNMVHELESALEYLRLQCDRRLTLQQKEHEQKMQLLLHHFKDQDGEGIIETLNKYEDKIQQLEKDLYFYKKTSRDLKKRLKDPVQGAVQWQRTLTEHHDAGDGVLNPEEAAVLSEELKWASRTENTKLNGREKEVDNSSSSLKTPPLTQQILEDGPDSLPVCGSLAPSSGQLQSSADKTEAH--AFTQSQSPPPPQLQPVRSIAQLQGVKPVKVCRRELRQISALELTLRRSSLGAGVRSVTADSLEEPEES-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7M6Z4-1", "uniprot_id": "KIF27_MOUSE", "id": "Q7M6Z4-1", "name": "Kinesin-like protein KIF27", "aln": "MEEIPIKVAVRIRPLLCKEVLHN------------------------------------------------------------------------HQVCVRDIPNTQ--------------------QIIIGRDRVFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGG-GHVASVVEGQKGIIPRAIQEIFQSISENPSIDFKIKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECQVESVEDVMSLLQVGNAARHTGTTQMNEHSSRSHAIFTISVCQVEKNAEAAENGEWYSHRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDP---RRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSDFDESLNSLKYANRARNIRNKPALNISPQADRMDEMEFEIKLLREALQSHQASISQASQASSENVPDQNRIHSLEEQVAQLQEECLGYQDCIEQAFAFLVDLKDAVKLNQKQQHKLQEWFSRTQEVRKAVLTPLPGNQGIGNLEEGPQHLTVLQLKRELKKYQCALAADQVVFTQKDLELEELRTQVQLMMQESKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSAELAKRSLSVPTSAKESCGDGPDARASEKRPHTAPFESHWGHYVYIPSRQDFKKVCSSTPVYSLDQVFAGFRTRSQMLMGHLEDQDEVLHCQFSDNSDDEDSEGQEKPRVRSRSHSWAKKPGSVCSLVELSDTQAESQRSYLGNGDLKMESLQESQEINLQKLRTSELILNKAKQKMRELTINIRMKEDLIKELIKTGNNAKSVSRQYSLKVTKLEHEAEQAKVELTETRKQLQELESKDLSDVALKVKLQKEFRKKMDAAKMRVQVLQKKQQDSKKLASLSIQNEKRASELEHNVDHLKYQKVQLQRRLREEGEKKKQLDAEIKRDQQKIKELQLKAGQGEGLNPKAEDQDGFNLNRRKSPFRSGDQFQKLDEQRKWLDEEVEKVLSQRQELEMLEEDLKKREAIVSKKEALLQEKSLLENKKLRSSQALSTDGLKISARLNLLDQELSEKSLQLESSP-TEEKMKISEQVQALQRERDQLQRQRNSVDERLKHGRVLSPKEEHLLFQLEEGIEALEAAIEFKNESIQSRQNSLKASFQNLSQSEANVLEKLVCLNITEIRAILFKYFNKVINLRETERKQQLQNKEMKMKVLERDNVVHELESALEHLRLQCDRRLTLQQKEHEQKMQLLLQHFKDQDGDSIIETLKNYEDKIQQLEKDLYFYKKTSRDLKKRLKDPAQGAAQWQRTLTEHHDAGDGVLNPEETTVLSEELKWASRTENTKLNGSEREVDNSSSSLKTQPLTQQIPEDGPDSLPARSSIAPSSGQLQSIADKTEAR--PFTHSQSPVPHQFQPVRSIGPLQGVKPVKLCRRELRQISAMELSLRRCSLGAGGRSMTADSLEDPEEN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VH2-1", "uniprot_id": "KIF27_HUMAN", "id": "Q86VH2-1", "name": "Kinesin-like protein KIF27", "aln": "MEEIPVKVAVRIRPLLCKEALHN------------------------------------------------------------------------HQVCVRVIPNSQ--------------------QVIIGRDRVFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGG-GHIASVVEGQKGIIPRAIQEIFQSISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDP---RRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKRELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTST-AEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYEDKIQQLEKDLYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGDGVLKPEGGGMLSEELKWASRPESMKLSGREREMDSSASSLRTQPNPQKLWEDIPELPPIHSSLAPPSGHMLGNENKTETDDNQFTKSHSRLSSQIQVVGNVGRLHGVTPVKLCRKELRQISALELSLRRSSLGVGIGSMAADSIEVSRKPRDLKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O16844-1", "uniprot_id": "COS_DROME", "id": "O16844-1", "name": "Kinesin-like protein costa", "aln": "-MEIPIQVAVRIFPHRELKDLLRSFGPTEPKKDAQAVDEGADSKDSEAQVPAAEKDNPSISETDPNGNAEQDSAADSKTIPDANGNDSGQKDYPDSAYCVQAIPISASALGLPSALPGGDPMDSIAAGLIQVGPHTVPVTHALPSSSSQEQVYHQTVFPLITLFLEGFDASVVTYGQRGQGKSYTLYGNVQDPTLTDSTEGVVQLCVRDIFSHISLHPERTYAINVGFVEICGGDVCDLLGMGN----------------------IHCTNVDAVFHWLQVGLSARQS---------LPAHTLFTLTLEQQWVSKEG-------LLQHRLSTASFSDLCGTERCGDQ-------PPGRPLDAGLCMLEQVISTLTDPGLMYGVNGNIPYGQTTLTTLLKDSFGGRAQTLVILCVSPLEEHLPETLGNLQFAFKVQCVRNFVIMNTYSDDN---------TMIVQPAEPVPESNSSAGPLSQAGPGDNFGLQFAASQWSKLVTNAEG----------LFSKLIDSKLITEVEKEQIEEWLFLKQECEECLSS--------------------TEAMRQQKQLVPILEAEEPEDVNSEAANSESPNSDNENDTDNESHRPDLDDKIES-LMEEFRDKTDALILEKHAEYLSKHPKAVMQSQDREIEAQPPEENGDDR-----------------------------------KVSIGSRRRSVQPGASLSTAELAMLNRVAS-----------------------QQPPPPIDPESVVDPLESSSGEGIRQAALAAAAATAPIEQLQKKLRKLVAEIEGKQRQLREIEETIQVKQNIIAELVKNSDTRSHAKQRFHKKRAKLEAECDKAKKQLGKALVQGRDQS-------------------EIERWTTIIGHLERRLEDLSSMKHIAGESGQKVKKLQQSVGESRKQADDLQKKLRKECKLRCQMEAELAK---------------------------------------------------------------------LRESRETGKELVKAQGSPEQQGRQLK---------------AVQARITHLNHILREKSDNLEEQPGPEQQETLRHEIRNLRGTRDLLLEERCHLDRKLKRDKVLTQKEERKLLECDEAIEAIDAAIEFKNEMITGHRSIDTSDRIQREKGEQMLMARLNRLSTEEMRTLLYKYFTKVIDLRDSSRKLELQLVQLERERDAWEWKERVLSNAVRQARLEGERNAVLLQRQHEMKLTLMLRHMAEETS------------------------ASSASYGERALAPACVAPPVQASSDFDYDHFYKGGGNPSKALIKAPKPMPTGSALDKYKDKEQRSGRNIFAKFHVLTRYASAAAAGSSGSTAEESTALIESTTTATATTTSTT----------------TTGAVGKVKDKALVSFRPEQLKRLMPAPTATKVTRQKNKIIIQDASRRN----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***::***** * : * . **: ** : :* :.... ..: ..*:*::** : **: ::**::*:*.:*** *.**:**: * : .::.:. :*:: .:::**. ** :*. : ::*.::*: *: *** : . : .. *: *::* :**:: :*::**::: * . *. :* :*. * **.*:** . . :::** * :***:* ** ..::** ::.:* *****:** *:*::* **** ...: *:*..*::* :.: :** :* .: : .:: :. :. . *.: . * :: .* ::* :. * :: .* *: :.: ::.::::*: ** .:.: : : *: *: * *:: :.: .* . : :.:.* .*.: : ::: : : *:::: : *:* :: * ... * . : * :: * * ** . :. : .: :.:. ::* . . .: *. . . . : : * . . * :**:. : ::::**: .*::*:::* **:*..: . ..::: * :*** :.::** :* :: * :: . ::: . : *::: :* ..: :: :. ::..:*::.*.. : * :**::**:* : : *::* : : *. . :. : :*. : : *: *: :.:*:. *:: * **. *: .. .*:: .: .::. *: :: * ..* :*.:*:..:**: :**: *:: :*.***::****::** * .::. :. : .:.* :: :* *. *:*::*::**.**::**::.** :* ::: : : : *..*: :*: :*. .* *::** *: *:*:*: :: . .:: :: * . : ::.. .* :*. : : : :. . . . ::. . :.::. . . .. . * * .. . .*.: . :. ::. *.. .:*::: . : : *. : ", "identical_positions": 226, "similar_positions": 454, "identity": "15.09%" }, { "cls_id": "homologset.agr.RGD:621072", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZH2-1", "uniprot_id": "BARD1_RAT", "id": "Q9QZH2-1", "name": "BRCA1-associated RING domain protein 1", "aln": "MP------RRPPRVCSGNKPPPVPAMEPATDGLWAHSRAALARLEKLLRCSRCANILREPVCLGGCEHIFCSGCISDCVGSGCPVCHTPAWILDLKINRQLDSMIQLYSKLQNLLHDNKGSDSKDDTSRASLFGDAERKKNSVKMWFSPRSKKIRCVVNKVSVQTQP---QKAKDDKAQEASVFEFVSATPPVVVSTRAKTASRTSAKKHPKKSVAKINREGNFRPETRDSRFDSKEKLKEEKVVSFSQTLVMENSRVN------GEIDLLASGSVVESVFSGSFAEVSLPLAEHIVSPDTVSKSEEAPEKKVCVEDRC-----PVGSDGNPKGCHRPPTSTSKKCGSNVPSASGEIREPTLLAENVVLVDCSSLPSGRLQVDVTLRRQ-SNASDDSLSLSPGTPPSLLNNS-THRQMMSKPSTVKLSSGIPARKRNHRGETLLHIASIKGDISSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKIVELLLQHNALVNTTGYHNDSPLHDAAKNGHIDIVKVLLSHGASRNAVNIFGERPVDYTDAENIRSLLLLPEKTDSFSTSQCSVQVNTGQRKSGPLVLIGSGLSSQQQKLLSKLETVLKAKKCAEFDNTVTHVIVPDE-EAQSTLKCMLGILNGCWVLKFDWVKACLDSQEREQEEKYEVPGGPQRSRLNREQLLPKLFDGCYFFLGGNFKHHPKEDLLKLIAAAGGRILSRKPKPDSDVTQTINTVAYHAKPDSDQRFCTQYIVYEDLFNCHPERVRQGKVWMAPSTWLISCVMAFELLPLDS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70445-1", "uniprot_id": "BARD1_MOUSE", "id": "O70445-1", "name": "BRCA1-associated RING domain protein 1", "aln": "MP------RRPPRVCSGNQPAPVPAMEPATDGLWAHSRAALARLEKLLRCSRCANILKEPVCLGGCEHIFCSGCISDCVGSGCPVCYTPAWILDLKINRQLDSMIQLSSKLQNLLHDNK--DSKDNTSRASLFGDAERKKNSIKMWFSPRSKKVRYVVTKVSVQTQP---QKAKDDKAQEASMYEFVSATPPVAVPKSAKTASRTSAKKHPKKSVAKINREENLRPETKDSRFDSKEELKEEKVVSCSQIPVMERPRVN------GEIDLLASGSVVEPECSGSLTEVSLPLAEHIVSPDTVSKNEETPEKKVCVKDLR-----SGGSNGNRKGCHRPTTSTSDSCGSNIPSTSRGIGEPALLAENVVLVDCSSLPSGQLQVDVTLRRK-SNASDDPLSLSPGTPPPLLNNS-THRQMMSSPSTVKLSSGMPARKRNHRGETLLHIASIKGDIPSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKVVELLLQHNALVNTPGYQNDSPLHDAVKSGHIDIVKVLLSHGASRNAVNIFGVRPVDYTDNENIRSLLLLPEENESFSTSQCSI-VNTGQRKNGPLVFIGSGLSSQQQKMLSKLETVLKAKKCMEFDSTVTHVIVPDE-EAQSTLKCMLGILSGCWILKFDWVKACLDSKVREQEEKYEVPGGPQRSRLNREQLLPKLFDGCYFFLGGNFKHHPRDDLLKLIAAAGGKVLSRKPKPDSDVTQTINTVAYHAKPESDQRFCTQYIVYEDLFNCHPERVRQGKVWMAPSTWLISCIMAFELLPLDS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99728-1", "uniprot_id": "BARD1_HUMAN", "id": "Q99728-1", "name": "BRCA1-associated RING domain protein 1", "aln": "MPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNELSDLKEDKPRKSLFNDAGNKKNSIKMWFSPRSKKVRYVVSKASVQTQP---AIKKDASAQQDS-YEFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEKEDGEFDSKEESKQKLVSFCSQPSVISSPQIN------GEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTPEKVCKNYLTSKKSLPLENNGKRGHHNRLSSPISKRCRTSILSTSGDFVKQTVPSENIPLPECSSPPSCKRKVGGTSGRKNSNMSDEFISLSPGTPPSTLSSS-SYRRVMSSPSAMKLLPNM-AVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLLLLPEKNESSSASHCSV-MNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVVPGD-AVQSTLKCMLGILNGCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRSRLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTVAYHARPDSDQRFCTQYIIYEDLCNYHPERVRQGKVWKAPSSWFIDCVMSFELLPLDS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QKB4-1", "uniprot_id": "A0A8M9QKB4_DANRE", "id": "A0A8M9QKB4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MFVPNNKKNMRIWFSPKSRKVRCCIHRPVELNTPNGVQQKKSTASPSSEDLAVFNFSSSSQESGPSTPPRAKMNKKTKKKRIGQNSRQAKAAQRPRTWIRSLQERKKLKLEVINKQWNTGEEADVDAIDETGDEDEKMSSGDDNRKPAKRVFFRLPHSQSEETFKPSQQRNLTPNHEKIVEFKDSEQQ---NSAALSLPDHDQQPIAEISPELNENELLQPSFSRVRKRSSSESLPKQPRITPEPKRRSSGEGAALIEDSSQSLKTFRPTNEKPVLSSLGTHDVLKKSPDVRHKQTCPVYMKRNHKGETALHLAASKGDVEGVRKLLAQGADPNLKDNAGWTPLHEACNVGHLGVVEELLQQGALLNTPGYQNDSPLHDAIRSGHIAVVKLLVERGASQSVLNIFGLRPVDYALTPEMKEVLRVAPEASHLITTSLRP---PASKAAGGVVLIGSELTQTQHKQINRAAQLLGGKQAKAFSSAVTHVVVPDVPIMPSTLTTLHGVLNGCWILNFSWLSCSLQAGSWVKESGYEAGDGPLRARANRGSLLPPLFDGCFFYMLGSFRKPPKDELLQLVKAGGGQLLKRLPKPDSDVTQTLNAAAYHAQAGSDQVLCTQYILYDPQSSYKPQKVRLGKVWSAPSTWLLDCIAAFRLLPVPEP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:*:.:::****:*:*:* : : . * *. : . . ... :.. . :. . ** ** :.: .:: : . . . :*. * : .* . . . :: .* : ::**. . : .:. . :*. .*. . : * : . :: : * . . :.: : *. : : . .: *:. :: * . . *.. :: : ..*.. : . ****:*** **:*: ***: .*. ** :* ***:**:**********. *** :** ***: **:**.**:******** :.**: :**:*:. ***:..:**** *****: .::.:* :. : . :: ...: * :*:*** *:. *:* :.. :* .*: *..:****:**. ***. : *:*.***:*:*.*:...* :*. ** ** *:* ** .*** *****:*:: *.*:: *:::*::*: *.**::*.* **********:*:.****:. *** :*****:*: . :*::** **** ***:*::.*: :*.***: . ", "identical_positions": 198, "similar_positions": 208, "identity": "25.0%" }, { "cls_id": "homologset.agr.RGD:621073", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88623-3", "uniprot_id": "UBP2_MOUSE", "id": "O88623-3", "name": "Ubiquitin carboxyl-terminal hydrolase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQLSSTLKRYTESSRYTDAPYAKPGYGTYTPSSYGANLAASFLEKEKLGFKPVSPTSFLPRPRTYGP-------------------------------------SSILDCDRGRPLLRSDIIGSSKRSESQTRGNERPS--GSGLNGGSGFS-YGVSSNSLSYLPMNARDQGVTLSQKKSNSQSDLARDFSSLRTSDGYRTSDGYRTSEGFRIDPGNLGRSPMLARTRKELCALQGLYQAASRSEYLTDYLENYGRKGSAPQVLTQAPPPSRVPEVLSPTYRPSGRYTLWEKSKGQASGPSRSSSPGRDTMNSKS-------------------AQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMR--DLGHTSSAHTALMEEFAKLIQTIWTSSP----NDVVSPSEFKTQIQRYAPRFMGYNQQDAQEFLRFLLDGLHNEVNRVAARP------KASPETLDHLPDEEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRG-YPEVTLMDCMRLFTKEDILDGDEKPTCCRCRARKRCIKKFSVQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLR--DLDLREFASENTN--------------HAVYNLYAVSNHSGTTMGGHYTAYCRSPVTGEWHTFNDSSVT-PMSSSQVRTSDAYLLFYELASPPSRM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U349-1", "uniprot_id": "UBP2_RAT", "id": "Q5U349-1", "name": "Ubiquitin carboxyl-terminal hydrolase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQLSSTLKRYTESSRYTDAPYAKSGYGTYTPSSYGANLAASFLEKEKLGFKPVSPTSFLPRPRTYGP-------------------------------------SSILDCDRGRPLLRSDITGGSKRSESQTRGNERPS--GSGLNGGSGFP-YGVTSNSLSYLPMNARDQGVTLGQKKSNSQSDLARDFSSLRTSDSYRTSDGYRASDGFRIDPGNLGRSPMLARTRKELCALQGLYQAASRSEYLTDYLENYGRKGSAPQVLTQAPP-SRVPEVLSPTYRPSGRYTLWEKNKGQASGPSRSTSPGRDTMNSKS-------------------AQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMR--DLGHTSSAHTALMEEFAKLIQTIWTSSP----NDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVAARP------KPSPESLDHLPDEEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRG-YPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRARKRCIKKFSVQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLR--DLDLREFASENTN--------------HAVYNLYAVSNHSGTTMGGHYTAYCRSPVTGEWHTFNDSSVT-PMSSSQVRTSDAYLLFYELASPPSRM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75604-1", "uniprot_id": "UBP2_HUMAN", "id": "O75604-1", "name": "Ubiquitin carboxyl-terminal hydrolase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQLSSTLKRYTESARYTDAHYAKSGYGAYTPSSYGANLAASLLEKEKLGFKPVPTSSFLTRPRTYGP-------------------------------------SSLLDYDRGRPLLRPDITGGGKRAESQTRGTERPL--GSGLSGGSGFP-YGVTNNCLSYLPINAYDQGVTLTQKLD-SQSDLARDFSSLRTSDSYR------------IDPRNLGRSPMLARTRKELCTLQGLYQTASCPEYLVDYLENYGRKGSASQVPSQAPP-SRVPEIISPTYRPIGRYTLWETGKGQAPGPSRSSSPGRDGMNSKS-------------------AQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMR--DLHHGSNAHTALVEEFAKLIQTIWTSSP----NDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRP------KSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRG-YPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLR--DLDLREFASENTN--------------HAVYNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVT-PMSSSQVRTSDAYLLFYELASPPSRM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QLD6-1", "uniprot_id": "A0A8M9QLD6_DANRE", "id": "A0A8M9QLD6-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRVSSTAKRYAGSS--YTSHYSS--YGSSLTPSLGSYERDKLPYKSSSSGFSSSSSSYLSSSASRSR-N----------------------------------YSSSSEPDRGRPIPRTDLLGG-RRSESLSRTPVKGY--GSGLNGGSGYSSYSYTPAPSSYLSSSPVSSSISLSRRKSVSQSDLTHDLSALGLSETSS-------------------GSGLKQSYLSRGSDVSDSYSSSRSSLGLSRSSTQEGLGSSG------------------------------LKSSSRFSSSYRSTSPVRESLNSKS-------------------AQGLVGLRNLGNTCFMNSILQCLSNTQSLRDYCLHNSHRR--DLNNNNRTHTALMEEFAKLIQTMWTSSS----SEAVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTVRP------RGNTEDFDHLPDEEKGKKMWSKYLEREDSKIVDLFVGQLKSSLTCSECGYCSTVFDPFWDLSLPIAKKG-YGEVSLMDCMRLFTKEDVLDGDEKPTCYRCKARRRCTKKFTVQKFPKILVLHLKRFSEARIRTSKLSTFVNFPMK--DLDLREFASDRSS--------------SAVYNLYAVSNHSGTTMGGHYTAYCCNPENGEWYTYNDSRVT-PMSASQVRSSDAYVLFYERAGL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3AST8-1", "uniprot_id": "A0A8M3AST8_DANRE", "id": "A0A8M3AST8-1", "name": "Ubiquitin carboxyl-terminal hydrolase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPVYSSPKYATGST--LLSPYSS--YDP-CDPTLAYIVRG----QPQLSRYAPSTSRYLSPSPCLARGV----------------------------------LFFPQEPERGRAALHSEPHVG-RYSESYSRLQVKGQ--LPRINRPRGRS-----PSRNGYTCMSPLSR-----QRRSVSQSDLMRELATLEICDQG------------------------------------------------AVERTVYAVKESA------------------------------IRGRTDYSGPLYWTS-----ENSKN-------------------AQGLVGLRNLGNTCFMNSILQCLSNTHDLRDYCLRNTHRT--DLNNNCRAKAALMDEFAKLTQTIWTSAS----NEAISPSDFKMQIQKYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTVKS------RAPVEDLDHLSEDEKGKRMWNKYLESEDSKVVDLFVGQLKSSLTCSECGFCSTVFDPFWDLSLPIAKT--SGEVSLNDCLRLFTKEDVLDGNERPTCHRCKTRRKCTKKFTIQKFPKILVLHLKRFSECRVRTSKLSTFVNFPLK--ELDLREFASDNSV--------------NAVYNLYAVSNHTGTSLGGHYTAYCRSPCTGEWYTYNDSRVS-PMSSSQVCSSDAYVLFYECATSS-RM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQ27-1", "uniprot_id": "UBP2_DROME", "id": "Q8IQ27-1", "name": "Ubiquitin carboxyl-terminal hydrolase Usp2", "aln": "MMLDIKKTRGFHKIPQASKLQSTTKTSSVVATSASSQNEVPSPGGSAGSKVGATNPVRAANQRFFLVSSYKDPTFLKAECDLAHAHVTTSKVKTTLQPHRRSRAGEDSRNNNYNTSRAPTLINMRRPSLFNGNQQPTTTNSTTINNTTSRNTTSNTSNGVLKYSVRSTTATATSTSTRNYGKLKPLNNNQTTAGVAMMNGHTNNNNNNTRNSSNINNGGNNNMQRQQQQHDDISFIDSDDPPATGGPEAGISTTKTSICYFKPITPPLQLRHEQNQVQQQEEQPQPSSSKSASHRYPRPKSTIIASAHSNFAASFEKFSGGLYRQTNGETNIESKTSSNARRYGIDSLSIKASIEKFNNLSGQKRQNPGSGSGIGPGSATASGLGGGRLSVASRSNHGSQAGGSSSNLQQRYSSDLDNIRVAAGYSSSLTRAAYRTTATMNSVSTPVAVTSELGGPISGDGGETATAMGQPTSKVTVRGAHSNRQPIECDSVVLTNKASKDATTAATPTVATATATHTPATSSVSTVTVTAAAPNSASDSTLARSGTGSSSTARSVLPPMTPTSSRYWDRDSGTSRSSIGTSSALNSSSLKHNSDDGYKTASSSRDEKSEGLCGLRNIGNTCFMNSVIQCLSHTQELTRFLRSHHGSR--SLSTK---DQQILHEFAKLIQEMWTAN-----VHTVTPMELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALNSGVKGE------TLNID--DNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLSVPLPSS---SRCKLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFSET--RWSKLSNIVEFPTSDSELNMGSYGANSNS--------------NVHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFNDNIVSDALSENHLVSSSAYILFYERT------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32571-1", "uniprot_id": "UBP4_YEAST", "id": "P32571-1", "name": "Ubiquitin carboxyl-terminal hydrolase 4", "aln": "---------------MEQNIISTIRDECIRHRSKYLTIAQLTAIAEAKINEFIITGKAKDQDLSSLLDKCIDILSIYKKNSKDIKNIISCKNKGAMISSNSVMIIQLNYVYYKVIHIIVTTNIPHLSEFAKIKLHKSTSDEGNGNNNNNEFQLMNIYNTLLETLLKDENIAKIKSFIKSSIKQTKLNHEQEECNLMRTGSYITSNQLNSLISSSANSASSQMEILLIDIRSRLEFNKSHIDTKNIICLEPISFKMSYSDHDLEKKSLITSPNSEIKMFQSRNLFKFIILYTDANEYNVKQQSVLLDILVNHSFEKPISDDFTKIFILESGFPGWLKSNYGR------------------------------------QVSSSFPSNNNIKDDSVYINGNTSGLSLQHLPKMSPSIRHSMDDSMKEMLVAPTPLNHLQQQQQQQSDNDHVLKRSSSFKKLFSNYTSPNPKNSNSNLYSISSLSISSSPSPLPLHSPDPVKGNSLPINYPETPHLWKNSETDFMTNQREQLNHNSFAHIAPINTKAITSPSRTATPKLQRFPQTISMNLNMNSNGHSSATSTIQPSCLSLSNNDSLDHTDVTPTSSHNYDLDFAVGLENLGNSCYMNCIIQCILGTHELTQIFLDDSYAKHININSKLGSKGILAKYFARLVHMMYKEQVDGSKKISISPIKFKLACGSVNSLFKTASQQDCQEFCQFLLDGLHEDLNQCGSNPPLKELSQEAEARREKLSLRIASSIEWERFLTTDFSVIVDLFQGQYASRLKCKVCSHTSTTYQPFTVLSIPIPKKNSRNNITIEDCFREFTKCENLEVDEQWLCPHCEKRQPSTKQLTITRLPRNLIVHLKRFDNLLNKNNDFVIYP-FLLDLTPFWANDFDGVFPPGVNDDELPIRGQIPPFKYELYGVACHFGTLYGGHYTAYVKKGLKKGWLYFDDTKYKPVKNKADAINSNAYVLFYHRVYGV---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . . . .. . . . * . : . . . . . :. : . : * . : **.*:**:*:**.::**: *:.* .: . : . **:* : ::. ::* .:* : .***.*** :*:**.**. :* ::*. . * : : * : *** ** * *.*. *. *..::** **:*:.. . .: *: * : : *: :* * :*. *: . *.::: ::*: *::*****.: : ..: * : .: . *.**.:: * *: ****.* . * ::*. . . . .*.**:***. . ", "identical_positions": 83, "similar_positions": 125, "identity": "8.46%" }, { "cls_id": "homologset.agr.RGD:621074", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R168-1", "uniprot_id": "SFRP1_RAT", "id": "Q9R168-1", "name": "Secreted frizzled-related protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------VRDSCEPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPPNATEASKPQGTTVCPPCDNELKSEAIIEHLCASEFALRMKIKEVKKENGDKKIVPKKKKPLKLGPIKKKELKRLVLFLKNGADCPCHQLDNLSHNFLIMGRKVKSQYLLTAIHKWDKKNKE---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4U3-1", "uniprot_id": "SFRP1_MOUSE", "id": "Q8C4U3-1", "name": "Secreted frizzled-related protein 1", "aln": "MGVGRSARGRGGAASGVLLALAAALLAAGSASEYDYVSFQSDIGSYQSGRFYTKPPQCVDIPVDLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHMGTQVFLCSLFAPVCLDRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPPNTTEASKPQGTTVCPPCDNELKSEAIIEHLCASEFALRMKIKEVKKENGDKKIVPKKKKPLKLGPIKKKELKRLVLFLKNGADCPCHQLDNLSHNFLIMGRKVKSQYLLTAIHKWDKKNKEFKNFMKRMKNHECPTFQSVFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N474-1", "uniprot_id": "SFRP1_HUMAN", "id": "Q8N474-1", "name": "Secreted frizzled-related protein 1", "aln": "MGIGRSEGGRRGAALGVLLALGAALLAVGSASEYDYVSFQSDIGPYQSGRFYTKPPQCVDIPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHAGTQVFLCSLFAPVCLDRPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPPNATEASKPQGTTVCPPCDNELKSEAIIEHLCASEFALRMKIKEVKKENGDKKIVPKKKKPLKLGPIKKKDLKKLVLYLKNGADCPCHQLDNLSHHFLIMGRKVKSQYLLTAIHKWDKKNKEFKNFMKKMKNHECPTFQSVFK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **************************************:*******************************************************************:**:***:*****************:************************** ", "identical_positions": 153, "similar_positions": 5, "identity": "48.73%" }, { "cls_id": "homologset.agr.RGD:621075", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLS4-1", "uniprot_id": "SFRP4_RAT", "id": "Q9JLS4-1", "name": "Secreted frizzled-related protein 4", "aln": "MLLSILVALCLCVRLALGVRGAPCEAVRIPMCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDVNCSSVLRFFLCAMYAPICTLEFLHDPIKPCKSVCQRARDDCEPLMKMYNHSWPESLACDELPVYDRGVCISPEAIVTDLPEDVKWIDITPDMMVQERSFDADCKHLSPDRCKCKKVKPTLATYLSKNYSYVIHAKIKAVQRSGCNEVTTVVDVKEIFKSSSPIPRTQVPLITNSSCQCPHILPHQDVLIMCYERRSRMMLLENCLVEKWRDQLSRRSTQWEERLQEQQRTTQDKKQIASRTS---RSNPPKPKGRSPASKPASPKKNIKARSAPKKSNPKKSTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1N6-1", "uniprot_id": "SFRP4_MOUSE", "id": "Q9Z1N6-1", "name": "Secreted frizzled-related sequence protein 4", "aln": "MLRSILVALCLWLRLALGVRGAPCEAVRIPMCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDVNCSSVLRFFLCAMYAPICTLEFLHDPIKPCKSVCQRARDDCEPLMKMYNHSWPESLACDELPVYDRGVCISPEAIVTDLPEDVKWIDITPDMMVQERSFDADCKRLSPDRCKCKKVKPTLATYLSKNYSYVIHAKIKAVQRSGCNEVTTVVDVKEIFKSLSPIPRTQVPLITNSSCQCPHILPHQDVLIMCYEWRSRMMLLENCLVEKWRDQLSRRSIQWEERLQEQQRTIQDKKQIASRTSRTSRSNPPKSKGRPPAPKPASPKKNIKARSAPKKSNLKKSAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6FHJ7-1", "uniprot_id": "SFRP4_HUMAN", "id": "Q6FHJ7-1", "name": "Secreted frizzled-related protein 4", "aln": "MFLSILVALCLWLHLALGVRGAPCEAVRIPMCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDVNCSAVLRFFLCAMYAPICTLEFLHDPIKPCKSVCQRARDDCEPLMKMYNHSWPESLACDELPVYDRGVCISPEAIVTDLPEDVKWIDITPDMMVQERPLDVDCKRLSPDRCKCKKVKPTLATYLSKNYSYVIHAKIKAVQRSGCNEVTTVVDVKEIFKSSSPIPRTQVPLITNSSCQCPHILPHQDVLIMCYEWRSRMMLLENCLVEKWRDQLSKRSIQWEERLQEQRRTVQDKKKTAGRTS---RSNPPKPKGKPPAPKPASPKKNIKTRSAQKRTNPKRV--", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ******** ::********************************************************:*********************************************************************************************.:*.***:****************************************************** ********************************* ********************:** *********:** ****: *.*** ******.**:.**.**********:*** *::* *: ", "identical_positions": 316, "similar_positions": 20, "identity": "90.03%" }, { "cls_id": "homologset.agr.RGD:621076", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62920-1", "uniprot_id": "PDLI5_RAT", "id": "Q62920-1", "name": "PDZ and LIM domain protein 5", "aln": "----MS-NYNVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQAHVRIGDVVLSIDGISAQGMTHLEAQNKIKACTGSLNMTLQRASAAAKSEPVAVQKGEPKEVVKPVPITS--PAVSKVTSTTNMAY--NKVPRPFG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVSSPKVTSIPSPSSAFTPAHAATSSHASPPPVAAVTPPPLSASGLHASANPSAAQCSSPPNTGKPAVHVPRQPTVTSVCSESAQELAEG-------------------------------------------------------QRRG---SQGDIKQQNGPPRKHIVER-----------------------------------------------------------------------------------------------------NTEFYHIPTHSDASKKRLIEDT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDWRPR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGTTQSRSFRILAQITGTEHLKESENDNAKKAN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STPEPSQQ----SASPLSAAESLESPGSNRPVVAGLRSAAAFKPVGST-SVKSPSWQRPNQAAPSTGRISNSASSSGTGAPMKPAVGPPQPSDQDTLVQR-------------------------------------------------------------------AEHIPAGKRTPMCAHCNQAIRGPFLVALGKSWHPEEFNCAH--CKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGSTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CI51-1", "uniprot_id": "PDLI5_MOUSE", "id": "Q8CI51-1", "name": "PDZ and LIM domain protein 5", "aln": "----MS-NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQAHVRIGDVVLSIDGISAQGMTHLEAQNKIKACTGSLNMTLQRASAAAKSEPVSVQKGEPKEVVKPVPITS--PAVSKVTSTTNMAY--NKAPRPFG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVSSPKVTSIPSPSSAFTPAHAATSSHASPTPVAAATPLHLSASGLHVSANLSADQCSSPPNTGKPAVNVPRQPTVTSVCSESAQELAEG-------------------------------------------------------QRRG---SQGDIKQQNGPPRKHIVER-----------------------------------------------------------------------------------------------------NTEFYHIPTHSDASKKRLIEDT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDWRPR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGTTQSRSFRILAQITGTEHLTESENDNTKKAN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STQEPSQQPASSGASPLSASEGPESPGSSRPSVAGLRSAAAFKPVGST-SVKSPSWQRPNQAAPSTGRISNNARSSGTGA----SVGPPQPSDQDTLVQR-------------------------------------------------------------------AEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAH--CKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96HC4-1", "uniprot_id": "PDLI5_HUMAN", "id": "Q96HC4-1", "name": "PDZ and LIM domain protein 5", "aln": "----MS-NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITS--PAVSKVTSTNNMAY--NKAPRPFG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPLFAASGLHANANLSADQSPSALSAGKTAVNVPRQPTVTSVCSETSQELAEG-------------------------------------------------------QRRG---SQGDSKQQNGPPRKHIVER-----------------------------------------------------------------------------------------------------YTEFYHVPTHSDASKKRLIEDT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDWRPR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGTTQSRSFRILAQITGTEHLKESEADNTKKAN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQR-------------------------------------------------------------------AEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAH--CKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IN44-1", "uniprot_id": "A0A0R4IN44_DANRE", "id": "A0A0R4IN44-1", "name": "", "aln": "----MSGKYSVVLQGPAPWGFRLQGGKDFNMPLSISRLTDAGKAAKAGVAVGDLVLSIDGISTDGMNHLEAQNKIKASSDKLNLSLQKASSLPKPD--VAPKDDCVEIIKPVPMTTSIPFSSDITNSTHITSSSNRSARPFG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAGSPPIAFIPSTASAFAPASTAQYPNPLSPPTDGSP--------------------NHQPTVPRPSVYN---TPINLYSDENACEVAMG-------------------------------------------------------QRRGLLESQGESCQLNGLPRVPITET-----------------------------------------------------------------------------------------------------DIEFYHVPTHGDASRKRIMEDT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDWRPR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGTSQSRSFRILAQITG----TESELDRAQEAE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAKK---------TTNEDVDDCQPSAHITCPVKTMIKAPAT--PVRNSAGFITPTFGVVSSSTPLGPALDR-------------PMPRPHPKDEASLVQR-------------------------------------------------------------------AEHIPAGTRTPMCAHCDMVIRGPFLVAMGKSWHPEEFTCAH--CSVSLSELGFVEEQGSVYCQHCYEEFFAPTCSRCHHKILGEVINALKQTWHVYCFLCASCQQPIRNDTFHLEDGEPYCERDFYSLFGTGCRGCDFPIEAGDKFLEALGGTWHDTCFVCTVCSVSLEGQTFFSKKGKPLCKKHAHALKI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZA47-1", "uniprot_id": "ZASP_DROME", "id": "A1ZA47-1", "name": "PDZ and LIM domain protein Zasp", "aln": "MAQPQLLQIKLSRFDAQPWGFRLQGGTDFAQPLLVQKVNAGSLSEQAGLQPGDAVVKINDVDVFNLRHKDAQDIVVRSGNNFVITVQRGGSTWRPHVTPTGN-VPQPNSPYLQTVTKTSLAHKQQDSQHIGCGYNNAARPFSNGGDGGVKSIVNKQYNTPVGIYSDESIAETLSAQAEVLAGGVLGVNFKKNEKEYQGDRSEVLKFLREEETGQSTPAFGNSHYEHDAPQQLQQPQQQYNQHQQHYHQQQQQQQSSTTRHVSAPVNSPKPPSTGGLPTGQNICTECERLITGVFVRIKDKNLHVECFKCATCGTSLKNQGYYNFNNKLYCDIHAKQAAINNPPTGTEGYVPVPIKPNTKLSASTISSALNSHGYGGHSNGYSNGNSTPAPAPVASSQATATVATVAPSAATAATAAATPQAATATDSPAATASSSDNMSAYVADEPSSIYGQISAESVALAPPPPQPPTAGGGDQPFEYVTLTGNVIRSVQAPGKGACPSYKVNQGYARPFGAAAPKSPVSYPPQQQQQSPRPAPGGQNPYATLPRSNVGQQGGEAVEELQPEFEEEDCYEMDIEVALAASRQSQRGSSFTWPPPQDDSHLAPTAAPLYIPPPETQHVVVSNPVQQVPPLPPGGATARLDPQPVVGTSANGAPQWQSYSAPQLTTASARQLAEQESSSDSYTSTSTTTTTTSEEYQRMYAAQVQAYQMQEQSGSEFDYQVDYASTQDSVQDYPSGRRSAQECVDSLAVPLSTYKLVDMVREVTPSPVTTPTQTPAPAAPTTRRVVFNDEPEIKELPQLPAELETIPEASEAVEDREGLVIEQRCQILESERKFQPTPEIKIEIAPVRQIPPTKIPNPMPKEWINPMIRVLTTAPEVPFHLVECPFPRPCGDDFEAEAAAAEAAKTQEVPEPLPPQVSAAPPATVSVEPSPAPLRESPPRGSRLSQAMVTAPEFELKFAPPADQGIPLPEETEPYMPPPIDTKPYLREDYRPKSPFVSALTTAPDRPFEGHFDKDVPIHMIDLPTPKEHLSMCDALCTAPERGYTPLNPENAMHRVDEEQKQQELKKREFQVLDHEEELGIRPEPPQSVEYYETRRDQPRKSSAFAAMQAFQPSREPLSSNTVSNAGSVADTPRASIVSALKEETDLEYQKYLKAQQRNQKRLDYFHQKEEELSGLQGQQLTQLQRELSNQQQNLLSQQQLQQSKLLQLQQCVQSQELQQQVQHLTQKSQQQPPQANQQQQQQQQQRGTQQQQHSQVTQRTQQQQQQVPQQVTQQQQQEHSLLSQTTLAETQTLQANAQSQSSASYSSKATACSNSSSTVPPANTSTAFAPAPAPAPTSIPVRPSAIAVQSSYCSSQFDVHELIEETAEELEHSEVLFPPPSPLSHLTKQGKAVQSGLHKADSIPKYQRNWTVLPTQSPIRTPEPQELRENVPLAFVDAPKAPVTSDSSTVHRPIAQVAAPTTVVAPSREREKERRPQLSVPIIVEDRSGPVTMAFQPLDELVRPDQALTPTRPYTPSLTNKPAPIVPFYQTEEKLVFEECSATHARNYNELNASPFPDRTRSPAPGPPPNPLNAIRAPRMKEPETKSNILSVSGGPRLQTGSITTGQSYQGQLLAHSEQSSQSASQSYNQQPERITEQRVGNLNIQQREQSSQLQQQAQSQTQSQTRSQVGNTQIERRRKVTEEFERTQSAKTIEIRTGSQSVSQSKAQSQSISQAQTQAQSQSQNQSDTERRSSYGKTGFVASQAKRLSCMEEEISSLTSQSQAISARASALGEGCFPNLRSPTFDSKFPLKPAPAESIVPGYATVPAATKMLTAPPPGFLQQQQQQQQRSAFSGYQATTSSVQQSSFASSSKATTSSLSSSSASASASASVARSSQSLTQASAITTTTNNQATTAYRSSNGSITKPNLASRPSIASITAPGSASAPAPVPSAAPTKATAPFKAPIVPKSVIANAVNAAAPPAPAVFPPDLSDLNLNSNVDNSPGAGGKSAGAFGATSAPKRGRGILNKAAGPGVRIPLCNSCNVQIRGPFITALGRIWCPDHFICVNGNCRRPLQDIGFVEEKGDLYCEYCFEKYLAPTCSKCAGKIKGDCLNAIGKHFHPECFTCGQCGKIFGNRPFFLEDGNAYCEADWNELFTTKCFACGFPVEAGDRWVEALNHNYHSQCFNCTFCKQNLEGQSFYNKGGRPFCKNHAR----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: .. *********.** ** :. :. .. : :* : ** *:.*:.:.. .: * :**: : . ..: :::*:..: :.. . : : .: . . .: :: *. .***. . ... : * .:* :.: :: . . .... . . .:: . . . : * *::. : * ** : : : * * ** ::: *: **:**: * :*.:. :: *:* .* ..: *: : : :: . . *. . : : .: .: :.: ... : . . *. : . : .* * *:* *: *****:.*:*: * *:.* *.: * .: :*****:* :**: *:*:::** *.:* ** *: :.*: : :* ** * * : : * *.****:.*** *: ** * * .* **:**** ::***. .:*. ** *:.* .****:*:.* .:*:**:**: ", "identical_positions": 130, "similar_positions": 188, "identity": "5.91%" }, { "cls_id": "homologset.agr.RGD:621077", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIJ5-1", "uniprot_id": "OGA_RAT", "id": "Q8VIJ5-1", "name": "Protein O-GlcNAcase", "aln": "MVQKESQAALEERESERNANPASVSGASLEPSAAPAPGEDNPSGAGAAAGTGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELN---TYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPSVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSD---EDIETDVLYSPQMALKLALTEWLQEFG-----------------------------------------------VPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLN----ATTVVT------------------------TVYQEPIMSQGAALSGEPSALTK---EEEKKQPDEEPMDMVVEKQEESEHKSD---NQILTEIVEAKMAEELKPMDTDKESIAESKSPEMSMQED-------------CINDIAPMQTDEQAN-----------KEQFVPGPNEKPLYAAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKG--------KDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSS------------------AQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMY-------DDGVGLPFQS---QPDLIGDKLVGGLLSLSLDYCFVLEDE-DGICGYALGTVDVTPFIKKCKISWIPFMQEKYTK-----PNGDKELSEAEKIMLSFHEEQ-----EVLPETFLANFPSLIKMDIHKKVT--DPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EQQ9-1", "uniprot_id": "OGA_MOUSE", "id": "Q9EQQ9-1", "name": "Protein O-GlcNAcase", "aln": "MVQKESQAALEERESERNANPAAASGASLEQSVAPAPGEDNPSGAGAAAVVGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELN---TYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSD---EDIETDVLYSPQMALKLALTEWLQEFG-----------------------------------------------VPHQYSSRQVAHSGAKTSVVDGTPLVAAPSLN----ATTVVT------------------------TVYQEPIMSQGAALSGEPSVLTK---EEEKKQPDEEPMDMVVEKQEEAEHKND---NQILTEIVEAKMAEELRPMDTDKESMAESKSPEMSMQED-------------CIPDVAPMQTDEQTQ-----------KEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKG--------KDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSS------------------AQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMY-------DDGVGFPFQS---QPDLIGDKLVGGLLSLSLDYCFVLEDE-DGICGYALGTVDVTPFIKKCKISWIPFMQEKYTK-----PNGDKELSEAEKIMLSFHEEQ-----EVLPETFLANFPSLIKMDIHKKVT--DPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60502-1", "uniprot_id": "OGA_HUMAN", "id": "O60502-1", "name": "Protein O-GlcNAcase", "aln": "MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELN---TYLYAPKDDYKHRMFWREMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLENEGSD---EDIETDVLYSPQMALKLALTEWLQEFG-----------------------------------------------VPHQYSSRQVAHSGAKASVVDGTPLVAAPSLN----ATTVVT------------------------TVYQEPIMSQGAALSGEPTTLTK---EEEKKQPDEEPMDMVVEKQEETDHKND---NQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQED-------------CISDIAPMQTDEQTN-----------KEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKG--------KDSEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSS------------------AQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMY-------DDGVGLPFQS---QPDLIGDKLVGGLLSLSLDYCFVLEDE-DGICGYALGTVDVTPFIKKCKISWIPFMQEKYTK-----PNGDKELSEAEKIMLSFHEEQ-----EVLPETFLANFPSLIKMDIHKKVT--DPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGRSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDC9-1", "uniprot_id": "Q9VDC9_DROME", "id": "Q9VDC9-1", "name": "protein O-GlcNAcase", "aln": "--------------------------------MADEAG-------------SQADGKRQFICGVIEGFYGRPWTTEQRKDLFRKLKSMGMGSSPSYMYAPKDDYKHRAYWRELYTVEEADHLSSLIAAAKEAGITFYYALSPGLDMTYSSPKEIATLKRKLDQVAQFGCEAYALLFDDIESELSKADKEVFQTFANAHVSVTNEIYTHLGSP-RFLFCPTQYCASRAVPTVQESEYLNTLGSKLNNEIDILWTGDKVISKNISLESIQEITEVLRRPPCIWDNLHANDYDQKRIFMGPYSGRSPELIPHLRGVMTNPNCEFYGNFVAIHSLAFWSRCSLD---------SKVNSSLSADIKLETENDDDLPAEFLSKNVYHPRLALKNAITEWLPEFFMKKEAWGPITKPQPQVQMVMPIIPIIPSINTCMSLTTTTTTSTSSRTVPPTVNTTQLQALADVCVVTSSLTPISNPVMNSLVSPTKVITNDDIINPIPTTAASNIELPKKIPISVVPVPIMETKSVEASVELALDNAVFDDNEIEPNSDSVKERLELEVNLEGKQEPVANLSVDTMLDDDSLSPLSGVVNEPMECSSSITSQVSPREEEAIKVVADDVLMESVNDVHSMHVESGTSSPISNAEMREETEAQSDRTNDNNTIEGEGITVDDLVLLCDLFYLPFEHGSRGHKLLVEFNWLKGNANVILQDRSAGGGGDAIKSDKPEVSEWHQRREQFDQLCSAVVELLIKIANCPNKEICHELYSYMWDISGALSLLNCYVKWLALGHFPQNTSSYTEGSYTWFSKGWKEAFMSGDQEPWVFRGGLIADLQRLMPVDSGNDLFVYKLPEQPTANYYLLRPYCNSDEQQVNDLCTRLYLQWRGELDGGRHIPFPLPANVPNIVADGLIGGYLTLSPQLCIVAYDESNRIIGYSCAALDVNIFRRNLELCWYTELREKYSRDICPLEGGEEVVQLVTSLVESYHDSSGNGALDQCPVEVSGSFPAVLISGTLREAEERDSGITKRMLTVLLAALRANGCFGAHVRVPQQDVAQVNFYSRIGFVDVYREEAT--KCIYMGRRF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .* . *.* *:*:***:********. ****:***:*:. :. :*:********** :***:*:****::* :**:**:* * * **:*****:*:*.***::*********:****.::*******: ::. ******.:**:*:**:***** :**.* ******:**.: . *.*.:* **.*:*.** *::**** **:**:*.:***:*::::::*.* ****:*********:*:***.***.****:*:**:******* .*:****:** * :..:: .. :*::* :****.*..* :: :. :* *::*** *:**** ** ** .: *: . *... . :: * :* .*.*:* :* ***. :. :. .* : :::: :*:.:.:. :* : : : *.: * : ::: . . * : .: . :.* :.::* :*: .: *: .*:.:. :. .* .*:: .* :*::** **.******:***.:* ::* **:**:.*:.*: : .. .*. ::.**:.* :*:::*. *: :: :::**.*: * :::***:***.. :*:::.:*:**. ... *: ******.***** .::***:*:*..****. * **:: * :*** .** .* .:* .:* *.* :** *:::.* *:** *:** : *:* ** : * **: .::**. * :: ::.* . ::***:: .*:: :. . .:: *:*:.. : * . ..**::: . ::. *..::* *:: **::*:***. **. .* :* ::***::* .:: : *. . : :** :", "identical_positions": 353, "similar_positions": 323, "identity": "32.81%" }, { "cls_id": "homologset.agr.RGD:621078", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4S8-1", "uniprot_id": "CRLF2_RAT", "id": "Q8R4S8-1", "name": "Cytokine receptor-like factor 2", "aln": "MRAVTWAIVAMLLPRVLGAIPTRTPRTGGVGDTLSVAIVCHDLESVEVTWGPGSAHHGLSANLSLEFRY-GNQVPQPCPHYFLLDS-VRAGCVLPMG-KGLLEVVLREGGGAKLFSRKKKASAWLRPRPPWNVTLSWVGD-TVAVSCPSHSYPGLEYEVQHRDDFDPE--WQSTSAPFCNLTVGGLDPGRCYDFRVRATPQDFYYGPEARPSKWTGVASLQGVGPTGSCTGPTLPRTPGTPTPPLALACGLAVALLTLVLLLALLRMRRVKEALLPGVPDPRGSFPGLFEKHHGNFQAWIADSQ-----AAVPTVPEQDKDDDVIRPQTKGVETQ-------EDDDVIAPGSP------CLGGGALMSVGGASFLMGDSGYTTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CII9-1", "uniprot_id": "CRLF2_MOUSE", "id": "Q8CII9-1", "name": "Cytokine receptor-like factor 2", "aln": "---MAWALAVILLPRLLAAAAAAAAVTS-RGD---VTVVCHDLETVEVTWGSGPDHHG--ANLSLEFRY-GTGALQPCPRYFLSGAGVTSGCILPAARAGLLELALRDGGGAMVFKARQRASAWLKPRPPWNVTLLWTPDGDVTVSWPAHSYLGLDYEVQHRESNDDEDAWQTTSGPCCDLTVGGLDPARCYDFRVRASPRAAHYGLEAQPSEWTAVTRLSGAASAASCTASPAP-SPALAPPLLPLGCGLA-ALLTLSLLLAALRLRRVKDALLPCVPDPSGSFPGLFEKHHGNFQAWIADAQ-----ATAPPARTEE-EDDLIHPKAKRVEPE-------DGTSLCTVPRPPSFEPRGPGGGAMVSVGGATFMVGDSGYMTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HC73-1", "uniprot_id": "CRLF2_HUMAN", "id": "Q9HC73-1", "name": "Cytokine receptor-like factor 2", "aln": "----MGRLVLLWGAAVFLLGGWMALGQGGAAEGVQIQIIYFNLETVQVTWNASKYSRT---NLTFHYRFNGDEAYDQCTNYLLQEG-HTSGCLLDAEQRDDILYFSIRNGTHPVFTASRWMVYYLKPSSPKHVRFSWHQD-AVTVTCSDLSYGDLLYEVQYRSPFDTE--WQSKQENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTYPSDWSEVTCWQRGEIRDACAETPTP--PKPKLSKFILISSLAILLMVSLLLLSLWKLWRVKKFLIPSVPDPKSIFPGLFEIHQGNFQEWITDTQNVAHLHKMAGAEQESGPEEPLVVQLAKTEAESPRMLDPQTEEKEASGGSLQLPHQPLQGGDVVTIGGFTFVMNDRSYVAL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . :: : . .: : :: .:**:*:***... : **::.:*: * . : *..*:* . :**:* . : .* :*. : :*:* .* :* : * * *:*: . ** .* ****:*. * * **:.. *::*: ***. :**.* **... ** :: **.*: *: . :*: .. * * . : * ..** *:. ***: :: ***. *:* **** . ****** *:**** **:*:* . . :. :: : : .*.: : . : . ** ::::** :*::.* .* :*", "identical_positions": 97, "similar_positions": 113, "identity": "25.26%" }, { "cls_id": "homologset.agr.RGD:621079", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJP0-1", "uniprot_id": "S20A1_RAT", "id": "Q9JJP0-1", "name": "Sodium-dependent phosphate transporter 1", "aln": "-MASTLAPITSTLAAVTASAPPKYDNLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSALLGAKVSETIRKGLIDVEKYNATQDLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVAKGQEGIKW--SELIKIVMSWFVSPLLSGIMSGILFFLVRAFILRKA---DPVPNGLRALPIFYACTIGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREVKS-SPSESPLMEKKNNLK-DHEETKMAPGDVENRNPVSEVVCATGPLRAVVEERTVSFKLGDLEEAPERERLP-MDLKEETNIDGTINGAVQLPNGNLVQFSQTVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGDEMETLTWPNADTKKRIRMDSYTSYCNAVSDLHSESEMDMSVKAEMGLGDRKGSSGSLEEWYD---QDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYETRDVTTKEATPIWLLLYGGVGICMGLWVWGRRVIQTMGKDLTPITPSSGFSIELASAFTVVVASNIGLPISTTHCKVGSVVSVGWLRS--KK-----------------------AVDWRLFRNIFMAWFVTVPISGVISAAIMAVFKHIILPV------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61609-1", "uniprot_id": "S20A1_MOUSE", "id": "Q61609-1", "name": "Sodium-dependent phosphate transporter 1", "aln": "-MESTVATITSTLAAVTASAPPKYDNLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSALLGAKVSETIRNGLIDVELYNETQDLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVANGQKGVKW--SELIKIVMSWFVSPLLSGIMSGILFFLVRAFILRKA---DPVPNGLRALPIFYACTIGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREVKS-SPSESPLMEKKSNLKEDHEETKMAPGDVEHRNPVSEVVCATGPLRAVVEERTVSFKLGDLEEAPERERLP-MDLKEETSIDSTINGAVQLPNGNLVQFSQTVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGDEMETLTWPNADTKKRIRMDSYTSYCNAVSDLHSESEMDMSVKAEMGLGDRKGSSGSLEEWYD---QDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYK-QEASTKAATPIWLLLYGGVGICMGLWVWGRRVIQTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRS--KK-----------------------AVDWRLFRNIFMAWFVTVPISGVISAAIMAVFKYIILPV------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WUM9-1", "uniprot_id": "S20A1_HUMAN", "id": "Q8WUM9-1", "name": "Sodium-dependent phosphate transporter 1", "aln": "-----MATLITSTTAATAASGPLVDYLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSVLLGAKVSETIRKGLIDVEMYNSTQGLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVAKGQEGVKW--SELIKIVMSWFVSPLLSGIMSGILFFLVRAFILHKA---DPVPNGLRALPVFYACTVGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREIKC-SPSESPLMEKKNSLKEDHEETKLSVGDIENKHPVSEVGPATVPLQAVVEERTVSFKLGDLEEAPERERLPSVDLKEETSIDSTVNGAVQLPNGNLVQFSQAVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGEEMEKLTWPNADSKKRIRMDSYTSYCNAVSDLHSASEIDMSVKAEMGLGDRKGSNGSLEEWYD---QDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYDTGDVSSKVATPIWLLLYGGVGICVGLWVWGRRVIQTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRS--KK-----------------------AVDWRLFRNIFMAWFVTVPISGVISAAIMAIFRYVILRM------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PFM1-1", "uniprot_id": "S20AB_DANRE", "id": "Q6PFM1-1", "name": "Sodium-dependent phosphate transporter 1-B", "aln": "MVSTTLATITIMSTLVGYTTGPLTDYMWLLIVGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETLGSVLLGAKVSETIRKGIIDVTMYKDIEHVLMAGSVSAMFGSAVWQLAASFLKLPISGTHCIVGATIGFSLVAKGQQGVKW--LELLRIVASWFLSPLLSGVMSAVLFYFVRMFILQKK---DPVPNGLRALPFFYAVTMGINLFSIMFTGAPMLGFDKLPWWGVLLISIGFGIITALIVWFAVCPRLKKKIECEVKSSSPSESPLMEKRELHEAHSPILKPVPEESSVLSSSTPTTPPLPPP----EERRVTFDIGDSDDADQ------KDCKESDLGGAPKTAHVHFTNG---------PAHIPSNGYSQYHTVHKDSGLYKDLLHKLHLAKVGDCMGEGGDRPIRRNNSYTSYTMAIIGMHG-DFKPKESEFRASEDGDKEKAGAQERKRIRMDSYTSYCNAVAENGTPEDLGE-GEVTLEMVDEDAGSSRSSLEEDRTDADKPEVSMLFQFLQILTACFGSFAHGGNDVSNAIGPLVALWLVYESGSVISSAPTPIWLLLYGGVGICVGLWVWGRRVIQTMGRDLTPITPSSGFSIELASAVTVVVASNIGLPVSTTHCKVGSVVAVGWLRS--RK-----------------------AVDWRLFRNIFMAWFVTVPISGLISAAIMALFNYVIL--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NV12-1", "uniprot_id": "S20AA_DANRE", "id": "Q6NV12-1", "name": "Sodium-dependent phosphate transporter 1-A", "aln": "MESTTLASLAAVSVLAAGAQTDMSDVLWLLILGFVIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILATIFETVGAMLLGAKVSETIRSGIIDVHMYNGSEAVLMAGSISAMFGSAVWQLAASFLKLPISGTHCIVGATIGFSMVARGHQGVKW--LELLRIVASWFLSPLLSGIMSAVLFYFVRKFILNKD---DPVPNGLRALPVFYAVTMGINLFSIMFTGAPMLGFDRIPWWGTLLISLGCAILTALVVWFIVCPRLKKKMQSKCLGPNIADTSGTQLVEKKPSSNGLMDHHPGPPRNYSP----VPQTPPA----DSNKVAFDIGGSAETD-------LDKKEFDTK-DQDCTHALNGSG---------GIVIPDLSGNQFHTVHKDSGIYKDLLHKLHLAKVGECIGEPVEKPIRRNNSYTSYTMAIYGIHG-SLKDGEGGSRTGLDG--------EKRRSRYDSYNSYCTAVADG--EAALED-AALAVGMEDEALREDVLEEDIDELEIDKPEVSTLFQFLQILTACFGSFAHGGNDVSNAIGPLVALWLIYDSASVAPSAPTPIWLLLYGGVGICTGLWIWGRRVIQTMGKDLTPITPSSGFSIELASAITVVVASNIGLPVSTTHCKVGSVVSVGWLRS--RK-----------------------AVDWHLFRNIFIAWFVTVPISGLISAAIMALFYYVILPLT-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTG0-1", "uniprot_id": "Q9VTG0_DROME", "id": "Q9VTG0-1", "name": "Phosphate transporter", "aln": "------------------MESFAPELLWMVVIGFLIAFVLAFGIGANDVANSFGTSVGSGVLTIRQACVLATICEISGAVLIGYKVSDTMRKGILEVGLYEGAEEVLMLGCVAALASSAVWLLVATFLKLPISGTHSIVGSTIGFSLVARGVQGLKW--STLGTIVGSWFISPVLSGIVSILLFLAIRRFILRAQ---EPLKAGFRSLPIFYGVTFFINVISVVLDGPKLLYMDNIPTWIALTASFGLSLLVALLTQLVVVPLQRRKIAKRLRAENPVKFNFEDSVESSPSGSPKKQRRPLSLVSEGKPLPAIAEITELVSLSDNSPRTFKLAPFGLAAKNN----NALGEEYKIDPQLIKKAEDLLG-------KASLDNTDLTITSLNFIDEQQQQQQQQQNGRKLQECFKRMQSPKEEQKSKTNSIG------TDLETGSTKATNNNLQVVESG----GSLDLMISSTLSPNSSKVPLIESKEALNEQEEELKRTTGGGRRTSGA-----------EETPEISMLFSFLQILTATFGSFAHGGNDVSNAIGPLIALYMIYREGSVMQQAESPIYILIYGGIGISVGLWLWGRRVIETIGNDLTKITSSTGFTIEVGAAITVLLASKIGLPISTTHCKVGSVVFVGHVSASGRKKKSQPNDQTDKETHNEVAPMDDGSVDWHLFRNIAYAWIVTVPVTALLSAGMMYVLCAIAVDDMGGA--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38361-1", "uniprot_id": "PHO89_YEAST", "id": "P38361-1", "name": "Phosphate permease PHO89", "aln": "--------------------MALHQFDYIFAIAMLFAFLDAFNIGANDVANSFASSISSRSLKYWQAMVLAGLCEFLGAVLAGARVSGTIKNNIIDSSIFTNDPAVLMLTMTSALIGSSCWLTFATAIGMPVSTTHSIVGGTIGAGIAAGGANGVVWGWSGVSQIIASWFIAPILAGAIAAIVFSISRFSVLEVKSLERSIKNALLLVGVLVFATFSILTMLIVWKGSPNLHLDDLSETETAVSIVLTGAIASIVYFIFFYPFYRRKVLDQDWT-----LKLIDIFRGPSFYFKSTDDIPPMPEG------------------HQLTIDYYEGR------------RNLGTTVSVEDEENKAASNSND----------SVKNKEDIQEVDLVRTETEPETKLSTKQYWWSLLKQGPKKWPLLFWLVISHG-----------------------------------------WTQDVIHAQVNDRDMLSGDLKGMYERSKFYDNR--------------------VEYIYSVLQAITAATMSFAHGANDVANATGPLSAVYVIWKTNTIGAKSEVPVWVLAYGGVALVIGCWTYGYNIIKNLGNKMILQSPSRGFSIELAVAITTVMATQLGIPTSTTQIAVGGIVAVGLCNKDLKS------------------------VNWRMVAWCYSGWFLTLPIAGLIAGIINGIILNAPRFGVEYQMT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::. :.:::**: **.:*********.:::.* :. ** :** : * *: * * :** *::..::: : :** :*: .*: * *: : :*:* **.***.*** .:.* * :*: * : *: ***::*:*:* :: ::* * :*. .: .: : .: *. * : :: *. * :* :. . . . : ::: : . * ::*: . : . .. : . . . . . . : : . . . . * . :. ::..** :** *****.***:** *** *::::: . *:::* ***:.: * * :* .:*:.:*..: :.* **:**:. *.*.::*:::*:* ***: **.:* ** :. *:*::. .*::*:*::.:::. : :: ", "identical_positions": 114, "similar_positions": 171, "identity": "15.75%" }, { "cls_id": "homologset.agr.RGD:621080", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53369-1", "uniprot_id": "8ODP_RAT", "id": "P53369-1", "name": "Oxidized purine nucleoside triphosphate hydrolase", "aln": "MSTSRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGAKRELLEESGLRVDTLHKVGHISFEFVGSPELMDVHIFSTDHVHGTPTESEEMRPQWFQLDQIPFADMWPDDSYWFPLLLQKKKFCGHFKFHGQDTILSYSLREVDEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53368-1", "uniprot_id": "8ODP_MOUSE", "id": "P53368-1", "name": "Oxidized purine nucleoside triphosphate hydrolase", "aln": "MSTSRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGAKRELLEESGLSVDTLHKVGHISFEFVGSPELMDVHIFSADHVHGTPTESEEMRPQWFQLDQIPFADLWPDDSYWFPLLLQKKKFCGHFKFQDQDTILSYSLREVDSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36639-4", "uniprot_id": "8ODP_HUMAN", "id": "P36639-4", "name": "Oxidized purine nucleoside triphosphate hydrolase", "aln": "MGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZWC3-1", "uniprot_id": "8ODP_DANRE", "id": "Q7ZWC3-1", "name": "Oxidized purine nucleoside triphosphate hydrolase", "aln": "MFTSKLLTLVLVVQPGRVLLGMKKRGFGAGKWNGFGGKVQTGETIEQAARRELLEESGLTVDTLHKIGNIKFEFIGETELMDVHIFRADNYEGEPAESDEMRPQWFDIDKIPFSQMWADDILWFPLMLQKKRFLGYFKFQGHDVIVEHKLDEVEDL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :*:* *****:** **************:********* *****:.*:*** ***** **:***:*:* ***:*..******:* :* .* *.**:**** **::*:*** ::*.** ****:****:* *:***:.:*.*:.:.* **: .", "identical_positions": 101, "similar_positions": 37, "identity": "64.74%" }, { "cls_id": "homologset.agr.RGD:621081", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVJ6-1", "uniprot_id": "TGM2_RAT", "id": "Q9WVJ6-1", "name": "Protein-glutamine gamma-glutamyltransferase 2", "aln": "-------------------------------------------------MAEELNLERCDLEIQANGRDHHT----ADLCQQKLVLRRGQRFRLTLYFEGRGYEASVDRLTFGAVTGPD--PSEEAGTKARFSLSDDVEEG----SWSASVLDQQDNVLSLQLCTPANAPVGQYRLSLETSTGYQGSS--FMLGHFILLFNAWCPADDVYLDSEAERREYVLTQQGFIYQGSVKFIKSVPWNFGQFEDGILDACLMLLDVNPKFLKDRSRDCSRRSSPIYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGISPMAWIGSVDILRRWKEHGCQQVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEYG-ELESNKSEMIWNFHCWVESWMTRPDLQP----GYEGWQAIDPTPQEKSEGTYCCGPVSVRAIKEGDLSTKYDASFVFAEVNADVVDWIRQSDGSVLKSINN-SLVVGQKISTKSVGRDDREDITYTYKYPEGSPEEREVFTRANHLNKLAEK------EETGVAMRIRVGDGMSLGNDFDVFAHIGN-DTSESRECRLLLCARTVSYNGVLGPECGTED-INLTLDPYSENSIPLRILYEKYSGCLTESNLIKVRGLLVEPAANSYLLAERDLYLENPEIKIRILGEPKQNRKLVAEVS-LKNPLSDSLYDCVFTVEGAGLTKEQKSVEVSDPVPAGDAVKVRVDLFPTDIGLHKLVVNFQCDKLKSVKGYRNIIIGPA-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P21981-1", "uniprot_id": "TGM2_MOUSE", "id": "P21981-1", "name": "Protein-glutamine gamma-glutamyltransferase 2", "aln": "-------------------------------------------------MAEELLLERCDLEIQANGRDHHT----ADLCQEKLVLRRGQRFRLTLYFEGRGYEASVDSLTFGAVTGPD--PSEEAGTKARFSLSDNVEEG----SWSASVLDQQDNVLSLQLCTPANAPIGLYRLSLEASTGYQGSS--FVLGHFILLYNAWCPADDVYLDSEEERREYVLTQQGFIYQGSVKFIKSVPWNFGQFEDGILDTCLMLLDMNPKFLKNRSRDCSRRSSPIYVGRVVSAMVNCNDDQGVLLGRWDNNYGDGISPMAWIGSVDILRRWKEHGCQQVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEFG-ELESNKSEMIWNFHCWVESWMTRPDLQP----GYEGWQAIDPTPQEKSEGTYCCGPVSVRAIKEGDLSTKYDAPFVFAEVNADVVDWIRQEDGSVLKSINR-SLVVGQKISTKSVGRDDREDITHTYKYPEGSPEEREVFTKANHLNKLAEK------EETGVAMRIRVGDSMSMGNDFDVFAHIGN-DTSETRECRLLLCARTVSYNGVLGPECGTED-INLTLDPYSENSIPLRILYEKYSGCLTESNLIKVRGLLIEPAANSYLLAERDLYLENPEIKIRVLGEPKQNRKLVAEVS-LKNPLSDPLYDCIFTVEGAGLTKEQKSVEVSDPVPAGDLVKARVDLFPTDIGLHKLVVNFQCDKLKSVKGYRNVIIGPA-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21980-1", "uniprot_id": "TGM2_HUMAN", "id": "P21980-1", "name": "Protein-glutamine gamma-glutamyltransferase 2", "aln": "-------------------------------------------------MAEELVLERCDLELETNGRDHHT----ADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPA--PSQEAGTKARFPLRDAVEEG----DWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGSS--FVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEFG-EIQGDKSEMIWNFHCWVESWMTRPDLQP----GYEGWQALDPTPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINR-SLIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEK------EETGMAMRIRVGQSMNMGSDFDVFAHITN-NTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQKRKLVAEVS-LQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVIIGPA-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLU2-1", "uniprot_id": "Q9VLU2_DROME", "id": "Q9VLU2-1", "name": "protein-glutamine gamma-glutamyltransferase", "aln": "MGQKLSCCQKCGDWKWCTSKDNEESTLRIRNANANYFTGIPQGDKTDGASSAVLGVLKVDLCLEDNHEEHHTSHFYAAAAKEALVVRRGEPFRLKIHFN-RDYSPSKDAISFIFTVADDTKPSPGHGTLNALVPHDGIDYLGDTLEWGAGIESHEGQTLTVLIKPPSTCPVTEWKLDIDTKLLGDGSRSYPLPLPIYVLFNPWCPDDQVYLEDRDQRKEYVMHDTTLIWRGSYNRLRPSVWKIGQFERHVLECSLKVLGTVGRIPP------AYRGDPVRVARALSALVNSVDDDGVLLGNWSEDFSGGVAPTKWTGSVEILQQFYKT-QKSVKFAQCWNFSGVLTTIARSLGIPSRIITCYSSAHDTQASLTVDVFIDANNKKLDAETTDSIWNYHVWNELWMQRPDLGVGEHGTFDGWQVVDATPQEASDNMYRVGPASVAAVKNGDILRPFDGGFVFAEVNADKLYWRYNGPSQPLKLLRKDTLAIGHLISTKAVLKWEREDITDTYKHAERSEEERSTMLKALKQSRHAFSRYYLNDNFNDIEFDMELKDDIKIGQSFSVVLKVSNKSESRTHMATGQISCDAVLYTGVGAVEVKTLG-FELELEPKSSDYVRMEVIFEEYYDKLSSQAAFQISAAAKVKDTDYDYYAQDDFRVRKPDIKFQLGEAAIVAQKELDVILRLENPLPIPLHKGVFTVEGPGIEQPLKFKIAEIPVGG--TAAATFKYTPPYAGRGTMLAKFTSKELDDVDGYRHYEIEPRPEDLLQPNGSHRSSNIIRRRTDVIA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : ** :: * .:*** * .:: **:***: * *.::*: *.*..* * ::* ... ** ** : * :: .* * : .::. .*:: : .*:..*: ::*.:::. :** : : :*:*.*** * ***:.. :*:***: : :*::** : :: *::**** :*: .* :*. :: : *..*: *.*.:*.:**. **:*****.*.:::..*::* * ***:**::: : : **:.*** *:.* *: *.****:*::* *.**** ::.* :: * : . :::.:.:: ***:* * * ** **** ::***.:*.**** *:. * **..* *:*:**: :*. ********* : * : .. * :.. :* :* ****:* : :***** ***:.* * ***..: :* : .: * . : ..: : :.: :.:.:*..*.*. :: * . :. . :.. :* *.*: . * * ::* *:* *.. : : :::*:* . *:.. ::: . : *: *: :.:*:**::: . :* : : *:***. .* *****.*: : * ** . . . .. * * .::.:* ..:*. *.*:*: * * ", "identical_positions": 211, "similar_positions": 251, "identity": "26.81%" }, { "cls_id": "homologset.agr.RGD:621083", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LVJ6-1", "uniprot_id": "A0ABK0LVJ6_RAT", "id": "A0ABK0LVJ6-1", "name": "G1/S-specific cyclin-D2", "aln": "----------------------------------------------------------------------------------------------------------------MSGPSGDRLAMELLCCEVDP-----VRRAVPDRNLL-EDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKET--IPLTAEKLCIYTDNSVKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQKE-----KLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVNALTCDALTELLAKITHTDVDCLKACQEQIEAVLLNSLQQFR-------------------------------------------------QEQHN-GSKSVEDPD------QATTPTDVRDVDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30280-1", "uniprot_id": "CCND2_MOUSE", "id": "P30280-1", "name": "G1/S-specific cyclin-D2", "aln": "--------------------------------------------------------------------------------------------------------------------------MELLCCEVDP-----VRRAVPDRNLL-EDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKET--IPLTAEKLCIYTDNSVKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQKE-----KLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDDEVNTLTCDALTELLAKITHTDVDCLKACQEQIEALLLNSLQQFR-------------------------------------------------QEQHNAGSKSVEDPD------QATTPTDVRDVDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30279-1", "uniprot_id": "CCND2_HUMAN", "id": "P30279-1", "name": "G1/S-specific cyclin-D2", "aln": "--------------------------------------------------------------------------------------------------------------------------MELLCHEVDP-----VRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKET--SPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQRE-----KLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQYR-------------------------------------------------QDQRD-GSKSEDELD------QASTPTDVRDIDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KUZ5-1", "uniprot_id": "Q7KUZ5_DROME", "id": "Q7KUZ5-1", "name": "", "aln": "MDLLCSEIIVYESDPSLYRLNKRQQQMSSPAIIRDQSSICSSLGDAESDSHPDAQNNAVVCNMKELVYIYASVDSAAKNPEQLEPPPPPPPPPPPPPTATQSIQSYPRYISQEPPTSHCQRLDERLTTTADPPATDNVNTAIGDPTLY-SDRCLENFLKVEEKHHKIPDTYFSIQKDITPPMRKIVAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLREPSCRALSVDLLVVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKNFPDINIGKVRGHAQAFISLAAKEHKFAKFSASTIAASSIAASMNGLKWH-LRSGHNLHFLLSLMTDLTSVEQAQVRDCMLHMEDIFKEHSRNLEPFLVNIDPKEMSTLYYKRRFQIHQSQHLSQISIRPLPLPKAPAECVEQHQQQHNFGSAAPHRTHTCKMQAQAQAQNEIQDVTF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * .** *. *: * .* .** *:*:*.:**:: . : .:**** * **::** **:*** *::*:***. **:**:****:. .. *::**:*.*.*::*****:*. .*:.: * :*****: ::*::*** **.:* *:*::*** **:* :: :** : ::. :* ***:**:*.*.:.*** :..* **:.*:.*:: **: . . . . * .*::.:* .: :: * ::* :: : :: . *:*:: ** : . . ** : .:::*: :", "identical_positions": 108, "similar_positions": 111, "identity": "22.55%" }, { "cls_id": "homologset.agr.RGD:621084", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C878-1", "uniprot_id": "UBA3_MOUSE", "id": "Q8C878-1", "name": "NEDD8-activating enzyme E1 catalytic subunit", "aln": "MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-QIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNY-EDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVN-FPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGDGVPLDGDDPEHIQWIFQKSIERASQYNIR--GVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLN--NYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSP--SAKLQEVLDYLTNSASLQMKSPAITATLE-GKNRTLYLQSVTSIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFT-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99MI7-1", "uniprot_id": "UBA3_RAT", "id": "Q99MI7-1", "name": "NEDD8-activating enzyme E1 catalytic subunit", "aln": "MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-QIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNY-EDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVN-FPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGDGVPLDGDDPEHIQWIFQKSVERASQYNIR--GVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLN--NYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSP--SAKLQEVLDYLTNSASLQMKSPAITATLE-GKNRTLYLQSVTSIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFT-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TBC4-1", "uniprot_id": "UBA3_HUMAN", "id": "Q8TBC4-1", "name": "NEDD8-activating enzyme E1 catalytic subunit", "aln": "MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-QIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNY-EDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVN-FPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIR--GVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLN--NYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSP--SAKLQEVLDYLTNSASLQMKSPAITATLE-GKNRTLYLQSVTSIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVX6-1", "uniprot_id": "UBA3_DANRE", "id": "Q7ZVX6-1", "name": "NEDD8-activating enzyme E1 catalytic subunit", "aln": "MAEGEEPEKKRRRIEELN-EKMVVDGGSGDRSEWQGRWDHVRKFLERTGPFTHPDFEASTESLQFLLDTCKILVIGAGGLGCELLKDLALSGFR-HIHVVDMDTIDVSNLNRQFLFRPKDVGRPKAEVAADFVNDRVPGCSVVPHFKKIQDLDETFYRQFHIVVCGLDSVIARRWMNGMLLSLLIY-EDGVLDPSSIIPLIDGGTEGFKGNARVILPGMTACIDCTLELYPPQIN-FPMCTIASMPRLPEHCVEYVRMLLWPKEKPFGDGVVLDGDDPKHIQWVYQKSLERAAEFNIT--GVTYRLTQGVVKRIIPAVASTNAVIAAACATEVFKIATSAYVPLN--NYLVFNDVDGLYTYTFEAERKENCSACSQVPQDMQFTP--SAKLQEVLDYLTENASLQMKSPAITTTLD-GKNKTLYLQTVASIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLKFIS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V6U8-1", "uniprot_id": "UBA3_DROME", "id": "Q9V6U8-1", "name": "Nedd8-activating enzyme E1 catalytic subunit", "aln": "---------------------MSVHSPNPGLILQSKRFNGLRNILEREGPFCKDGFAASSENLEFLQTKCQVLIIGAGGLGCELLKDLALMGFG-NLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFINARVPTCRVTPHFKKIQDFDESFYQQFHLVVCGLDSIVARRWINGMLLSMLRYEEDGTIDTSSIVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPPQVN-YPLCTIANTPRLPEHCIEYVKIIQWEKQNPFG--VPLDGDDPQHIGWIYERALERSNEFNIT--GVTYRLVQGVVKHIIPAVASTNAAIAAACALEVFKLATSCYDSMA--NYLNFNDLDGIYTYTYEAEKSENCLACSNTPQPLPIEDPNTTTLEDVIKLLCDSPRFQLKSPALTTVMKDGKRRTLYMSGVKSIEEATRKNLTQSLGELGLHDGQQLTVTDATSPSAMTLQLKYQSNEVEMV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99344-1", "uniprot_id": "UBA3_YEAST", "id": "Q99344-1", "name": "NEDD8-activating enzyme E1 catalytic subunit", "aln": "-------------------------------------------------------------------MDCKILVLGAGGLGCEILKNLTMLSFVKQVHIVDIDTIELTNLNRQFLFCDKDIGKPKAQVAAQYVNTRFPQLEVVAHVQDLTTLPPSFYKDFQFIISGLDAIEPRRFINETLVKLTLE-----SNYEICIPFIDGGTEGLKGHVKTIIPGITACWECSIDTLPSQQDTVPMCTIANNPRCIEHVVEYVSTIQYP---------DLNIESTADMEFLLEKCCERAAQFSISTEKLSTSFILGIIKSIIPSVSTTNAMVAATCCTQMVKIYNDLIDLENGNNFTLINCSEGCFMYSFKFERLPDCTVCSNSNSN---------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::*::********:**:*:: .* ::*::*:***:::******** .*:* .**: ** ::* *.* *..*.:.: : :**::*::::.***:: .**::* *:.: : . :*:*******:**:.:.*:**:*** :*::: *.* : *:****. ** ** :*** : : *: :.. .: :: ::. **: ::.* :: : *::* ***:*::*** :**.*. ::.*: .. *: :* :* : *::: *: :* .**: . ", "identical_positions": 104, "similar_positions": 113, "identity": "21.71%" }, { "cls_id": "homologset.agr.RGD:621085", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LQP7-1", "uniprot_id": "F1LQP7_RAT", "id": "F1LQP7-1", "name": "", "aln": "MAPSADPG-------MVRMALLLLPPLWLLPLTGGSQRAEPMFTAVTNSVLPPDYDSNPTQLNYGVAVTDVDHDGDFEIVVAGYNGPNLVLKYNRAQSRLVNIAVDERSSPYYALRDRQGNAIGVTACDIDGDGREEIYFLNTNNAFSGVATYTDKLFKFRNNRWEDILSDDINVARGVASLFAGRSVACVDRMGSGRYSIYIANYAYGDVGPDALIEMDPEASDLSRGILALRDVAAEAGVSKYTAGRGVSVGPILSNSASDIFCDNENGPNFLFHNQGNGTFVDAAASAGVDDPHQHGRGVALADFNRDGKVDIVYGNWNGPHRLYLQMSAHGKVRFRDIASPKFSTPSPVRTVIAADFDNDQELEVFFNNIAYRSSSANRLFRVIRREHGDPLIEELNPGDALEPEGRGTGGVVTDFDGDGMLDLILSHGESMAQPLSVFRGNQGFSNNWLRVVPRTRFGAFARGAKVVLYTKKSGAHLRIIDGGSGYLCEMEPVAHFGLGRDEASSVEVTWPDGKMLSRSVANREMNSVLEILYPRDEDKLQNTAPLECGQGFSQQDNGHCMDTNECIQFPFVCPRDKPVCVNTYGSYRCRTNKRCSRGYEPNEDGTACVAQVAFLGG----------YSSAAFRLSEPLSQASYLS---LGLGLCLQFYAL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R555-1", "uniprot_id": "CRAC1_MOUSE", "id": "Q8R555-1", "name": "Cartilage acidic protein 1", "aln": "MAPSADPG-------MVRMALLLLPPLWLLPLTGGSQRAEPMFTAVTNSVLPPDYDSNPTQLNYGVAVTDVDHDGDFEIVVAGYTGPNLVLKYNRAQNRLVNIAVDERSSPYYALRDRQGNAIGVTACDIDGDGREEIYFLNTNNAFSGVATYTDKLFKFRNNRWEDILSDDVNVARGVASLFAGRSVACVDRTGSGRYSIYIANYAYGDVGPDALIEMDPEASDLSRGILALRDVAAEAGVSKYTAGRGVSVGPILSSSASDIFCDNENGPNFLFHNQGNGTFVDTAASAGVDDPHQHGRGVALADFNRDGKVDIVYGNWNGPHRLYLQMSAHGKVRFRDIASPKFSTPSPVRTVIAADFDNDQELEVFFNNIAYRSSSANRLFRVIRREHGDPLIEELNPGDALEPEGRGTGGVVTDFDGDGMLDLILSHGESMAQPLSVFRGNQGFSNNWLRVVPRTRFGAFARGAKVVLYTKKSGAHLRIIDGGSGYLCEMEPVAHFGLGRDEASSVEVTWPDGKMVSRSVASEEMNSVLEILYPQDEDKLQNTAPLECGQGFSQQDNGHCMDTNECIQFPFVCPRDKPVCVNTYGSYRCRTNKRCNRGYEPNEDGTACVAQVAFLGG----------YSSAAFRLSEPLSQASYLS---LGLGLCLQLYAL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ79-1", "uniprot_id": "CRAC1_HUMAN", "id": "Q9NQ79-1", "name": "Cartilage acidic protein 1", "aln": "MAPSADPG-------MSRMLPFLLL-LWFLPITEGSQRAEPMFTAVTNSVLPPDYDSNPTQLNYGVAVTDVDHDGDFEIVVAGYNGPNLVLKYDRAQKRLVNIAVDERSSPYYALRDRQGNAIGVTACDIDGDGREEIYFLNTNNAFSGVATYTDKLFKFRNNRWEDILSDEVNVARGVASLFAGRSVACVDRKGSGRYSIYIANYAYGNVGPDALIEMDPEASDLSRGILALRDVAAEAGVSKYTGGRGVSVGPILSSSASDIFCDNENGPNFLFHNRGDGTFVDAAASAGVDDPHQHGRGVALADFNRDGKVDIVYGNWNGPHRLYLQMSTHGKVRFRDIASPKFSMPSPVRTVITADFDNDQELEIFFNNIAYRSSSANRLFRVIRREHGDPLIEELNPGDALEPEGRGTGGVVTDFDGDGMLDLILSHGESMAQPLSVFRGNQGFNNNWLRVVPRTRFGAFARGAKVVLYTKKSGAHLRIIDGGSGYLCEMEPVAHFGLGKDEASSVEVTWPDGKMVSRNVASGEMNSVLEILYPRDEDTLQDPAPLECGQGFSQQENGHCMDTNECIQFPFVCPRDKPVCVNTYGSYRCRTNKKCSRGYEPNEDGTACVGTLGQSPGPRPTTPTAAAATAAAAAAAGAATAAPVLVDGDLNLGSVVKESCEPSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2E1-1", "uniprot_id": "A0A8M6Z2E1_DANRE", "id": "A0A8M6Z2E1-1", "name": "", "aln": "MRRAITDERRWTFFHMAMLAWMLLLTVRVSGLSWG-QRTEPMFTSVTQSVFPPDYENNPTQLNYGVAVTDVDGDGDLEMFVSGYNGPNLVLKYDKFKKRLVNIAVDNRSSPYYALRDRQGNAIGVTACDIDGDGREEIYVLNTNNAFSGRATYTDKLFKFRNGRYEDLLNDDVNEHRDVANRVAGRSVACVDRKGTGRYSIYIANYASGTVGPHALIEMDESSSDPSKGIVVLSNVAEQAGVNKFTGGRGVVVGPILSQTLPDIFCDNEYSPNFLFRNNGDGTFTDVAAQVGVDDPMQHGRGVALADFNRDGKTDIVYGNWNGPHRLFLQLSNNRKKRFKDIATQKFSMPSPVRTVIAADFDNDNELEVFFNNIAYRGPSANRLFRVSRREHGDPQIEELNVGEAAEPEGRGTGAAVTDFDGDGLLDLLVTHGESAAQPISVYRVTQGSSNKWLRVIPRTQFGAFARGAKVIVYTKRNGPHTRIIDGGSGYLCEMEPVAHFGFGKDVATSVEVFWPDGRSVARPLEPSDMNKVMEIHYPENEEEATPALEIECGPGFELNENGRCTDQDECTQFPSVCPSERPVCTNTYGSFKCRANKRCNQGYEPNDEGTACVAQVAYFGG----------NRSSASKLLVSCLWPLVLT------FLAVFTACLGP-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q5Y3-1", "uniprot_id": "A0A8M9Q5Y3_DANRE", "id": "A0A8M9Q5Y3-1", "name": "", "aln": "----------------MRMWWACLLALGLFAVS----HAQPMFSVTTDTVLPPDALHNPTQLNYGMAVTDVDGDGDLEVVVAGYNGPNLVLKYNLNQNKLLNIAVDDHSSPYFALRDPAGNAIGVTACDVDGDGREEIYFLNTNNAFSGRATYADKLFKFRNGRFEDLLSDDINIRRGVANHMAGRSVACVDRKGTGRYSIYVANYASGNVGPHALIEMDEASSDVEKGIIALTNVAPQVNVNKYTGGRGVVVGPILSDARSDIFCDNENGPNFLFKNNGDGSFSDVASAAGVEDRYQHGRGVALADFNGDGKTDIVYGNWNGPHRLYLQDS---QERFKDVATKAFATPSPIRTIIAADFDNDLQLEVFFNNIAYQGQAPNRIFRVSRRLNSDPVITELDVGEAAEPQGRGTGATITDFDGDGLLDLLVAHGESASQPISVFKVNQGSSNNWLRVIPRTRFGAFARGAKVVMFTKHSGSHTRIIDGGSGYLCEMEPVAHFGLGTDEATSIEVYWPDGRSIARPLESADMNTVIEIAYPNEGE-----------------ESALTSDTQ-----VWVHAKEEEESEHTL-------HKQCGEGFTVNTNG-RCTALIS-------------SSESSVSSSSPPALVFIFLS-----FSLSLQ-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . :: :::***: .*::*:*** ********:****** ***:*:.*:**.********: :.:*:*****::****:**** **********:*********.********* ***:********.*:**:*.*::* *.**. .********** *:******:**** * ***.****** :** .:**:.* :** :..*.*:*.**** ******.: .******* .*****:*.*:*:* *.*: .**:* ************ ***.*************:** * : **:*:*: *: ***:**:*:****** :**:*******:. :.**:*** ** :.** * **: *:* **:*****..:*******:***:::**** :**:**:: .** .*:****:***:**********:::**:.*.* ********************:* * *:*:** ****: ::* : :**.*:** **.: : :.. * : * . :. . :* :*:*..*: * :* *.. :. ::. . * : ", "identical_positions": 340, "similar_positions": 147, "identity": "50.82%" }, { "cls_id": "homologset.agr.RGD:621087", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88583-1", "uniprot_id": "SOCS3_RAT", "id": "O88583-1", "name": "Suppressor of cytokine signaling 3", "aln": "MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVETQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGAPSFSLPPTEPSFEVQEQPPAQALPGGTPKRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35718-1", "uniprot_id": "SOCS3_MOUSE", "id": "O35718-1", "name": "Suppressor of cytokine signaling 3", "aln": "MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGTPSFSLPPTEPSSEVPEQPPAQALPGSTPKRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14543-1", "uniprot_id": "SOCS3_HUMAN", "id": "O14543-1", "name": "Suppressor of cytokine signaling 3", "aln": "MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGAPSFPSPPTEPSSEVPEQPSAQPLPGSPPRRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************************************************************:***********************************************:***. ****** ** ***.**.***..*:***************************************************************", "identical_positions": 214, "similar_positions": 8, "identity": "95.11%" }, { "cls_id": "homologset.agr.RGD:621088", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q7N9-1", "uniprot_id": "E9Q7N9_MOUSE", "id": "E9Q7N9-1", "name": "Dynein axonemal heavy chain 11", "aln": "MAAQE---------EGTVLRLSPSE----------QEDEEDEEAAAARRVQRFALDPRVRFLGGRLRQALRFPEETWGQYLESDDHR--------------------------------------------QVLGDFLESTGPASLVFSVATAGRLSASP---------------EIPRDVKHKLVYFAKKMTEN--MGESDFSQTILFGEIPR-SLLTHVTAFLDEILVPVLSNKNNHTSWSCFISQDVEHHTEVMKNKMHIFRGKMSRR---THLPIPTIAENIDLDQHYLVTRPQSDERRILHAIESLVIKWSHQIQEIIEKDSAHPLLSG-------------LHPTPETELDFWTMRHDNLKCIYSQLQAPIVLKMVKILRTRQSSYLPALKGIFTTVENALLEAQDVELHLRPLRRHIHSLQEAEFPQTRILIAPLLHTICLIWSHSKFYNTPARVIVLLQEFCNLFIDQARAYLSPEDLLKGEIEDALEKVQVAISVLKTFQNSFFKYRK-----------------GLTSYFTRNTEQRSWDFQSHLVFGR-FNKFLDRLVKIEDMFVTILEFEKLERLEFGGSKGAVLNAQIHSTSEEFIECCKVFQQSTYDPSDCDD---MEFESDYFKFKSRTLDFDRRLGTLLCEGLSNCSGLESAFKLLTIFGNFLEKPVVMEMFSPHYSTLLNMFNAELDVCKQLYDEHMKQIEHG---HEILNKNMPFTSGNIKWARMLLERLQMFWSNFTSLHYLFPDSPDE---------AAVCQKYAEMTTLLDQFESHIYSEWRRNVDETCEFNLNQPLVKFSPINGLLSVNFDPKLVAVLREVKYLLMLKKS--------DIPDSALGIFQKRNIILKYIGNLELLVQGYNKLKQT-LLEVEYPLIEDELGAIDEQLRVAATWLTWQDDFWVYMERVQVATAELECRVSQTQSNMLTIQQTMQAWAEWPLLPR----------RETRREAALTLDDKGDLFAKKYKLIREDGCKIHNLVEENRKLFRADPSLDSWK------------IYVEFIDDIVVEGFFQAILHDLDFFLRNTEKQLKP-----------------------------------------------TPFFQAQMLLMPPEIVFKPPLEKEAGDGFYDLVEEMLCGSFRVSAQMGRVAAH----------------------------------------LDIADYQNDMD------NMLGLAEVRQEIMNRVADVINKVLEFRSSLETYSYLWVDDRVEILRQFLLYGHAVPSEEMDAPASEDIL--------QPPTLEQFKEQIDIYEALYIQMSKFDDFRVFNSWFKVDMRPFKLSLLNVIKKWSWMFQEHLLRFVVDSLSELQGFIKQTNAGLQRQLCEGDHDGLVDIMGHLLAVRSRQRATDELFEPLKETIMLLESYGQKMPEQVYAQLEELPERWETTKKIAAMVRHEVSPLQNAEVTLIRKKCILFDEKQAEFRERFRSYAPLGFKAENPYAVLDKANQELEALEEEMEQMQNSARLFEVALPEYKQMKQCRQEIRLLKGLWDVIIYVRRSIDNWTETQWRQINVEQMDLELRRFAKEIWSLDKAVRVWDAYSGLEGTVKDMTTSLRAIAELQNPALRDRHWQQLMKAIGVRFSINDSTTLSDLLAVQLHRVEDDVRDIVDQAVKELGTEKVITDVSHTWEALEFSYEAHH-RTGTPLLKSDEQLFETLEHNQVQLQSLLQSKYVEYFIEQVLSWQNKLNVADAVIFTWMQVQRTWSHLESIFVCSEDIRVQLVEDARRFDKVDAEFKELMFETAKVKNVLEATCRP-HLYEKLKDFQHRLSLCEKALAEYLETKRVTFPRFYFISSADLLDILSKGAQPKQVTHHLVKLFDSISDLQFEDNLDVSTHKAVGMFSKEK-EYVPFQ-------AGCECIGHVESWLLQLEQTMKDTVRLAITEAITAYEEKPRELWIFDFPAQVALTGSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELSPGDRQKVMTICTIDVHARDVVAKLISQKVVSPHAFTWLSQLRHEWEDSRK------------------HCVVNICDAHFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYRSIGNIYKGLVQTGAWGCFDEFNRIAVEVLSVVAVQVKMIHDAIRNGRKRFVFLGETIPLKPSVGIFITLNPGYAGRTELPENLKALFRPCAMVAPDTELICEIMLVAEGFVDARSLARKFISLYTLCEELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDVPVFLGLVSDLFPALDVPRQRKPHFEQMVKQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKPVWSDLNPKAVTTDELFGFIHHATREWKDG---------LFSSILREQANLTHDGPTWIVLDGDIDPLWIESLNTVMDDNKVLTLASNERVALKPSMRLLFETHHLRTATPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYIPVCLEKLRTSFKAITSVPESSLVQTICTLLECLLTPEN-------------------------IPPDSPKETYEVYFAFACVWTFGGTLLRDQLSDYQADFSRWWHKEMKAVKFPSQGTIFDYYLDHKTKKFLPWTDKVPQFSMD----ADAPLKTVLVHTPETTRLRYFTELLLCKGKPIMLVGNAGVGKTVFLSNTLASLSEN-------------------------------------------YIVSCVPFNYYTTSAALQRILEKPLEKKAGRNYGPKGNKK-LVYFIDDLNMPEVDLYGTIQPHALLRQHIDYGHWYDRHKIMLKEIRNCQYVACMNPMVGSFTVNPRLQRHFTVFAFNFPSLDALTTIYGQIFSFYLQQ--QAFCPSVLRAGPSLIQATIAFHQMMAESFVPTAIKFHYNFNLRDLSNIFQGILFAS--PECLKS-------------LEDLARLWLHETSRVYGDRLIDTNDFDLFQRKMLETAHKYFKGVDANALLRQPLVYCHFASGGEDPCYMPVKDWEGLKAVLMEMVDNYNELHSAMHLVLFEDAMQHVCRISRILRIPQGHALLIGVGGSGKQSLSRLAAYICSLEVFQITLTEGYGAQELRVDLANLYVRTGAKNMPTVFLLTDAHVLDESFLVLINDLLASGDIPDLFSDEDMDKIISGIRNEVRGLGLVDSRENCWAFFLARVRQQLKMVFCFSPVGHTLRVRARKFPAIVNCTAIDWFHEWPQEALVSVSRRFIEEIEG-IEPQHKDSISLFMAHVHTSVKEVSAWYYQNERRYNYTTPRSFLEQISLFKSLLKKKREEVKQKQEHLGNGIQKLQTTASQVGNLKSRLASQEAELQLRNLDAEALITKIGLQTEKVSREKAIADAEERKVAAIQTEASQKQRECEADLLKAEPALVAAKDALNTLNRVNLTELKTFPNPPNAVTNVTAAVMVLLAPRGRVPKDRSWKAAKIFMGKVDDFLQALINYDKEHIPENCLKVVNEQYLKDPEFNPNLIRTKSFAAAGLCAWVINIIRFYEVYCDVEPKRQALAQTNLDLAAATEKLEAVRRKLVDLDHNLSRLTASFEKATAEKVRCQEEVNQTNKTIDLANKLVSELESEKIRWGQSIKSFETQEKTLCGDVLLTAAFVSYIGSFTRQYRQELVDCKWIP-FLQQKVSIPIAEGLDLIAMLTDDATIATWNNEGLPSDRMSTENATILTHCERWPLMIDPQQQGIKWIKNKYGPDLKVTHLGQKGFLNTIETALAFGDVILIENLKETVDPVLGPLLGRNTTKKGKFIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEGQLLAEVVSIERPDLERLKLVLTKQQNDFKIELRQLEDDLLLRLSAAEGSFLDDTDLVERLETTKATAAEIEHKVTEARENERKINETRECYRPVAARASLLYFVISDLRRINPVYQFSLKAFNTLFHRAIEQADKVEDTQERICALIESITHATFLYASQALFERDKLTFLSQMAFQILLRRNEIHPLELDFLLRFTVEHTYSSPVDFLTAQSWSAVKAVALMEEFRGLDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLIILRAVRPDRMTYALRNFVEEKLGAKYVERTRLDLGKAFEESSPSTPVFFILSPGVDALKDLEVLGKRLGFTIDSGKFHNVSLGQGQELVAEMAMEKAAAGG-HWVILQNVHLVAKWLGTLEKLLEKFSQGS----HRDYRVFLSAETVPSQHEPIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEMCSKDQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFSPGDLTICTNILYNYLEANPNVPWEDLRYLFGEIMYGGHITDAWDRKLCRVYLEEFMNPSLIEDEVMLAPGFAAPPYSDYSGYHQYIEDTLPPESPALYGLHPNAEIELLTVTSNTLFRTLLEMQPRNAVSQEELGQSTEDKVKNILDDILERLPEEFNMAEIMQKNPNRSPYVLVCFQECERMNVLIREIRVSLQHLDLGLKGELTLSPDVETQLSALSYDRVPDTWNKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDRMCLTIDVTKKTKEDYGHPPREGAYLHGLHLEGARWDIQSGALVDARLKELTSMMPVIFAKAVPVDRQEIKHAYECPVYKTKARGPTYVWTFRLRSKDRIAKWVLAGVALLLEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96DT5-1", "uniprot_id": "DYH11_HUMAN", "id": "Q96DT5-1", "name": "Dynein axonemal heavy chain 11", "aln": "MAAQVAAREARDFREAPTLRLTSGAGLEAVGAVELEEEEENEEEAAARRARSFAQDARVRFLGGRLAMMLGFTEEKWSQYLESEDNR--------------------------------------------QVLGEFLESTSPACLVFSFAASGRLAASQ---------------EIPRDANHKLVFISKKITES--IGVNDFSQVVLFGELPA-LSLGHVSAFLDEILVPVLSNKNNHKSWSCFTSQDMEYHIEVMKKKMYIFRGKMSRR---TLLPIPTVAGKMDLDQNCSENKPPSNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNG-------------LHLSPQAELDFWMMRRENLSCIYDQLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQETEFPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSPEDLLRGEIEESLEKVQVAVNILKTFKNSFFNYRK-----------------KLASYFMG-RKLRPWDFQSHLVFCR-FDKFLDRLIKIEDIFATTLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDCTN---MEFESDYVAFKSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPVVMEIFSLHYSTLVHMFNTELDVCKQLYNEHMKQIECG---HVVLNKNMPFTSGNMKWAQQVLQRLQMFWSNFASLRYLFLGNPDH---------ALVYQKYVEMTTLLDQFESRIYNEWKSNVDEICEFNLNQPLVKFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQ--------DIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQT-LLEVEYPLIEDELRAIDEQLTAATTWLTWQDDCWGYIERVRAATSELEHRVERTQKNVKVIQQTMRGWARCVLPPR----------REHRREAAFTLEDKGDLFTKKYKLIQGDGCKIHNLVEENRKLFKANPSLDTWK------------IYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQLKP-----------------------------------------------APFFQAQMILLPPEIVFKPSLDREAGDGFYDLVEEMLCNSFRMSAQMNRIATH----------------------------------------LEIKNYQNDMD------NMLGLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDEMDAHANEEIPE-------QPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKKWSWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRATDELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTLIRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEELEALEEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHY-RTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCRP-NLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEK-EYVPFQ-------AECECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKVVSPQAFTWLSQLRHRWEDTQK------------------HCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKPVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPEN-------------------------VPSDSPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEMKAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMD----PDVPLQTVLVHTTETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSED-------------------------------------------YIVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKK-LIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNCQYVACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQ--QAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFAS--PECLKG-------------PLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETKG-IEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVP-FLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKYGMDLKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLGRNTIKKGKYIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTHLSPVDFLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGG-HWVILQNVHLVAKWLGTLEKLLERFSQGS----HRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKNVLDDILEKLPEEFNMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLRGPSYIWTFRLKSEEKTAKWVLAGVALLLEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KI05-1", "uniprot_id": "Q0KI05_DROME", "id": "Q0KI05-1", "name": "", "aln": "--------------MSDAAAMASSD----------EEGLPAGSTSGRQRVQRDYSDARLERVAAYTTTTMRLKPDKWTKMMACDDLRRIVVEWQHGHRRVLVMTLSPGGDLVPRSCLSDLYLPYSVQSARGSIPSAMLPAEDEAMATVTAAVSAVVSATPGALLIPLPPASSSFTTLDGVPRGKCAYFVRRNTSDGPLTASNFAESVLYGDFPVHSKIETMSLLFDDVLQPLLEQ--AQSQWPAIVRKDLQARIKEVRNTLTEIKGKTNNRTILSLLVSPTIVEEVFAHVSQGHLRPALDP-KFRNLLEEMFINWTTQMHDIVLERSECQPLGSTTQSAGHQPKYITLVSLPAQEIGFWTNRKLNLQNIYEQLRESTHKTLAQILERIESVYYEPYATAFRKLVAAWLEAQDVSLWLQPLLRQTAAFNSVQFSNGHDLVAPLVHIVHLVWSNARYYRSTQRMSVLLRCICNMLVHRAAEDLELQLLFQGDADEGLLKINRTIAVLELFKQRMLDYKERYAGSQVLLPALSEGAAAVASSPSPDDQQQLWRFCHEDVFGQTLDGFSLQLLELRQVFEAAVQFQQLEKLEVGGLRGKILTERVREIFGEFKVLFEQWSNVDIDLTATVASKWKCFRREQTLFFSRMQLLEQKLATVLLQAFEQCHSWMHLLRLTLMFGSLLQREAVRPELARVLPHILFIYDTEMEQLEDSVGEVLLGYEIRGLAALPLANNFPPIANAMMWLEQHISRCDEFGAKELSQLVEQLLKEKSELQTLPIQWNSLLSRRNILTTKLSNLQMKIWISWHECVDKLIIQGLDESVLSRSQDLSQLHLNFSQVLFTLLKETKYLLALQATGSLSGDLFQLPEPLLTLYGHRDAYWERRIRLIKIGEFYNGIRSGECAAAELQLIRNDLASIDEHVEVACQQLTWRNYNDELVAGIFEQSRDLFARLQQSHGNLDAILASMRRWSREPLHQRSLYGRNLLDLRHQQDRVRLRLLQCDETKMLLNRLLIANFCLFFNYESQEFQLYSRDLSVQEFIREFPEEQRRQYNKYLASVDELICREVREAMRISLEYLYKEMTATATATTTPTAPPVDPGCSAGMARLVLQQITTPQATSTAGAGASGAPPTANDAPLFEVKLELTETEIRFSPAFDASVENNFQQIVEQLLLDIKQTCDCMPRIVADNAPSEDDEDDDTATVDYEQELRWEPREDRAQELQERKKKDLELEQEQGDPKPQAVQFNLLAAAKAYSQKMECTADGLEMLERAIRDALADTVAAASAYAAKFQAYAFLWTQQSSEVLAACMQTAREQTHHVSAGGYAIMETFKKEIENYNEVHDAIDQCENRECINGWLALDIKPLKYGLLNLACKWSHMCKKWLLRYVQGTLKELNAFIARGFETLQLHIARQDFATLLRVLAIMSEIREREPYADNVFKPLKEIMGLLKTYNVEFEPQLLRGIEQLPQQWQQLKHSSTVKQEALQDTRFHQQQRVTALIGLHTCHLQHYARQFQKMPFFRVPCPQVYDVCDEVYLRLHRFRRQQRLYTRWARLLDIQPPDPATLQFCEVELRRVKQLWDFVRVIESCIVAWHATPWLLIDTDDMEHECKKFTRDLRTLDKCIREWAPYVHIVGVLRELVASLRAITELQNPAITERHWMELMQLTKLSYKCNKSTRLAQLLTLQLQHHEEDIKNTVDRAIKEMTVTKVLDEIKATWAHLEFELEQHHTRPHIQLLKVSEELIETLDDNQMQLQNISTSKHIEYLLDKLTHWQKVLGGIDTLIVNWFEVQRKWIYLECIFIGSADIRAQLPADAANFERIDEDFTALLAKVQEVRVVMQVVLRHDDVLAQLLQLQHRLAVCEKALNDYLETKRLAFPRFYFISAADLLDILSNGNNPQVIDRHLIKLFDSILRLQYETN----TPNALGMHSKENDEYVPFVSFDPDQPAFIVCGGRVELWLRAIIQQMRSTLHELFRRALRVFGEKPRELWLYDWPAQVALCCSQISWTADVNRSFGCMEEGYEGVMKELHKRQIAQLNALINLLLGELSPGDRQKIMTICTIDVHSRDVVGKIIASKVDNSLAFQWQSQLRHRWDDDQAGSSSGRASTAISCGGGDEDCFANICDAEFRYAYEYLGNTSRLVITPLTDRCYITLTQSLRLRLAGATAGPAGTGKTETTKDLGRALGVMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRICVEVLSVVAVQVKTIQEAIKMHKTQFIFMGERISLEPSVGIFITMNPGYAGRTELPENLKTLFRPCAMIVPDFALICEIMLMAEGFQDARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGTLKRDDHSRPEDQVLMRALRDFNIPKIVTEDVPIFMGLIGDLFPALDVPRKRVFEFEKTIRRAVNEIKLQPEEGFLMKVVQLQELLDVRHSVFIVGNAGTGKTKIWQTLRETYRIQKLKPVCHVLNPKALSNDELFGIVNPTTREWKDG---------LFSSIMREQANMPPGNPKWIVLDGDIDPMWIESLNTLMDDNKILTLASNERISLKREMRLLFEVGHLKAATPATVSRAGILYINPQDLGWSPYVSSWLETRVDMIERGILNALFEKYFPCLMQRQRD-FRRITPITDMAMIQMTCHLLECLLDSDEGNADGRGRGSATGGAANPHSLHHGELSHEAMVMALETIFVYATVWSFGSALSQDVIIDWHREFHKWWIGEFKDIKLPSQGTVFDYQLNVQTLKFQPWSELAAHQSLEGQIDSETPLQNVLISTAETIRLAYFLKLLIDRNLACMLVGNSGCGKGAIFRQLFGQYANDQELLEVAVSAATAGDSSHQQQSGNPAGAVVVRRKASSSATPLLTTVQATHFNFYTSSEIFQKMLDRPLEKKSGRCYAPSGPKRRLIYFVNDLNMPEVDAYGTVQPHTIMRQFMDYRQWYDRQRLQLKDIRHCQFAACMNPTAGSFTIDPRLQRHFCVFSVAPPGEDTLHHIYGSILSSHLESPSQGFTKEIRSIGSLLVRVGIALHRRVEYAFLPTALKFHYLFNLRDLTGIYQGLMNSVGAPASAGGGGASGFGGTICSRPSELMRLYVHEAFRVYHDRLVDPYDIKSFKSSIRDIFKKDFEDFDEDFVFAEPLIYSHFAQSLVDQKYMPLKSWDSLYQLLIEAQASYNEVVGYMNLVLFEDAMIHVCRINRILESPRGNALLIGVGGSGKQTLARLAAFISSLNVSQIQIKRGFGLLDMREEIGNLYMKVGLKNLASVFLISDAQIPDESILMLINDLLASGEIPELFNDDQLDTITNGIRNEVKQSGTLDTKENCWRYFVEKVRRLLKVVLCFSPVGQTLRVRARKFPAIISRTAIDWFHEWPKSALESVSQKFLNEINGILEPALVPPIGCFMAYVHGTVNQISRIYLQNEKRYNYTTPKTFLEYIFLYRKLLVDKNGEFAERIARLQSGMSKLAECARQVDTLKHQLAIQEVQLAAKNAAADKLIVIVSAESEKVKRERYIASEEEKRVRIIEEDVSIKTKMCEEDLRQAEPALVAAQAALNTLNKNNLTELKSFGSPPKAVVNVCAAVMVLLASNGKIPRDRSWKASKLMMVRVDQFLNDLLNYNKDNIHPNIIETL-QEYLKDPEFNPDKVVQKSVAAAGLCAWVINLHRYHQVFLIVGPKQQALQDSHQELLEARERLQYLKAKINNLEAKLAEIQAEFENAVGEKQRCQREADKTAFTIDLAHRLVNGLANENVRWKESVQSLLAKIGTLPGDILLISSFLSYVGCFTRRYREELQHKMWLPNFRKIDPHIPHTEGVDTLALFSDDAQIAAWNNEGLPMDRMSTENATILQYSTRWPLMIDPQLQGIKWIKNRFGTDLVVLRLRQKGFLEALEKSISQGDTVLIEQIEESMDTVLEPLLSRALIKKGRYLRIGDKEIEFHASFRLILHTKMANPHYKPEMQAQTTLINFTVTPDGLEEQLLAEVVKIERPDLEQMKTEVTVQQNKFKISLKALEDELLARLASSGENVLDDHALVINLENTKRTVDEIEAKVREARVTTLQIDDTRNIYRSAAKRAAILYFVLTDLSRINPIYKFSLKSFMNVFRQAIAMAAESKNYEKRVLHLVESITLQTYRYTLRGLFEADKLTFTSHMTLRILIAAEQVAKDETDFLLRFPHDPTTLSPLDFVGRSAWGGIKSLTLIEHFYGIDKDMENYTKRWRKFMASDTPEREQFPGEWKHRTPLQKLCIIRSLRPDRMTYAMRQFVEQTMGRSYAEIQTPPFGAIFQELNAATPAFFILSPGVDPIRDVERYGQRQGFHSESDTLVNISLGQGQELLAEQAIIGALESGQQWVILQNIHLVVNWLPTLEKLIERIVLQSESKGESNFRLFISAEPAPDPQYHVIPQGILESSLKVVNEPPSGMAANLHKAWDNFSQDALETCTQEAEFKSILFALCYFHAVAGERRKFGPQGWNKVYPFNIGDLTISSNVLHNYLEGSNRIPWEDLRYLFGEIMYGGHITDDWDRRLCQTYLEELLQQDLIDGDFELCPGFPAPPNLDFEGYHSYITEMLPEESPLLYGLHPNAEIGFLTTASEQLLRTIFELQPRESELSSHCGAPREELVKIMIDDFLDKLQDEFNLQALLNRVERKTPFVVVALQECERMNALIREIKRSLRELMLGLRGELTITQEMERLDHAIFYDHVPAAWARLAYPSMLGLQSWFADLLHRIKELAGWLNDFKLPCAIWLGGLFNPQSFLTAIMQESARKHDLPLDRMLISCDVTKKQKDDVTLPPMEGAFVHDLYMDGASWDCQLNSIVALRPKEMLCAMPVIYIKSIVQEKQELQRVYECPLYKTRSRGNTYVWTFNLKTRERPSRWILGGVALLLQP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P62912-1", "uniprot_id": "RL32_RAT", "id": "P62912-1", "name": "Large ribosomal subunit protein eL32", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPN----------------------IG---------------------------------------------------------------YGSNKKTKHMLPSGFRKFLVHN-------VKELEVLLMCNKSYCAEIAHNVSSK--------------NRKAIVERAAQLAIRVTNP----------NARLRSEENE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *** : ****.. *: .* : :. :: ::: ::: * *: :* :.* : : : . .::* : ::.*:.:: ** ..:: . * *.**. * :. : : * *. ", "identical_positions": 25, "similar_positions": 47, "identity": "0.51%" }, { "cls_id": "homologset.agr.RGD:621089", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LL01-1", "uniprot_id": "A0ABK0LL01_RAT", "id": "A0ABK0LL01-1", "name": "", "aln": "MHRGTLWCNYILGIVCLEG-RMLGSHLHQVCWLRSVVSESYREDFIREAGVTLEVGGTDLEPSQALEKEALAG-----HEVLGADSGGIITLNRETVQGG------------------------------KGVMNS------PPSRILRRRKREWVMPPISVPENGKGPFPQRLNQLKS--NKDRGTKLFYSITGPGADSPPEGVFTIEKETGWLLLNMPLDREKIVKYELFGHAVSENGASVEEPMNISIIVTDQNDNKPKFTQDTFRGSVPEGVMPGTSVMQVTATDEDDAINTYNGVVAYSIHSQEPKEPHDLMFTIHKSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAEAVVQILDTNDNAPEFQPQKYEAWVPENAVGHEVQRLTVTDLDSPNSPAWRATYHIVGGDDGDHFTVATHPETNQGILTTKKGLDFEAQNQHTLYIEVTNEASFAVKLPTATATVVVHVEDVNEAPVFVPPSKVIEAQEGISIGELVCVYTAQDPDKEE-QKISYSILRDPASWLAVDPDSGQITAAGILDREDEQFVKNDIYEVMVLATDNG-NPPTTGTGTLLLTLTDINDHGPIPEPRQIIICNQSPVPQVLNITDKDLSPNSSPFQAQLTHDSDIYWMAEVSEKGDTVALSLKKFLKQDTYDLHLSLSDHGNREQLTMIRATVCDCHG-----QVLNDCPRPWKGGFILPVLGAVLALLTLLLALLLLVRKK-RKVKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDVAPTFIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDSLLVFDYEGSGSDAASLSSLTSSTSDQDQDYNYLTEWGSRFKKLADMYGGGEDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10287-1", "uniprot_id": "CADH3_MOUSE", "id": "P10287-1", "name": "Cadherin-3", "aln": "-------------MELLSGPHAFLLLLLQVCWLRSVVSEPYRAGFIGEAGVTLEVEGTDLEPSQVLGKVALAG-----QGMHHADNGDIIMLTRGTVQGG------------------------------KDAMHS------PPTRILRRRKREWVMPPIFVPENGKGPFPQRLNQLKS--NKDRGTKIFYSITGPGADSPPEGVFTIEKESGWLLLHMPLDREKIVKYELYGHAVSENGASVEEPMNISIIVTDQNDNKPKFTQDTFRGSVLEGVMPGTSVMQVTATDEDDAVNTYNGVVAYSIHSQEPKEPHDLMFTIHKSTGTISVISSGLDREKVPEYRLTVQATDMDGEGSTTTAEAVVQILDANDNAPEFEPQKYEAWVPENEVGHEVQRLTVTDLDVPNSPAWRATYHIVGGDDGDHFTITTHPETNQGVLTTKKGLDFEAQDQHTLYVEVTNEAPFAVKLPTATATVVVHVKDVNEAPVFVPPSKVIEAQEGISIGELVCIYTAQDPDKED-QKISYTISRDPANWLAVDPDSGQITAAGILDREDEQFVKNNVYEVMVLATDSG-NPPTTGTGTLLLTLTDINDHGPIPEPRQIIICNQSPVPQVLNITDKDLSPNSSPFQAQLTHDSDIYWMAEVSEKGDTVALSLKKFLKQDTYDLHLSLSDHGNREQLTMIRATVCDCHG-----QVFNDCPRPWKGGFILPILGAVLALLTLLLALLLLVRKK-RKVKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDVVPTFIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDSLLVFDYEGSGSDAASLSSLTTSASDQDQDYNYLNEWGSRFKKLADMYGGGEDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22223-1", "uniprot_id": "CADH3_HUMAN", "id": "P22223-1", "name": "Cadherin-3", "aln": "-------------MGLPRG-PLASLLLLQVCWLQCAASEPCRAVFR-EAEVTLEAGGAEQEPGQALGKVFMGCPGQ-EPALFSTDNDDFTVRNGETVQER------------------------------RSLKERNPLKIFPSKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKS--NKDRDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKLPTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDKEN-QKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNG-SPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEGDTVVLSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHG-----HVET-CPGPWKGGFILPVLGAVLALLFLLLVLLLLVRKK-RKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDVAPTIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G176-1", "uniprot_id": "A0AC58G176_DANRE", "id": "A0AC58G176-1", "name": "Cadherin-1", "aln": "------MRLCCLFGKSLPAVLDIYLLFARVMEAIGAVWSGTLIVLFQGVSYVFAEET-LLHAEK--STVNFSYGSARDEEVYSNEGNHMDIIVNSPPQFS--------------------------NLLVEEFQSSSEG--------RRRRKREWAIPPFTVLENDKSALPKILFKLKANLDGVPDEDIRYSITGEGADQPPVGIFTVTSMSGIVKVTQQLDREKKALYLLMAHANSVKG-IKEKPTNLTIIVADQNDNRPVFVENPFNGHVSESATIGHEFMAVTATDADDPD-TFNADVRYKIVSQDPLLPNPNMFEINLVTGGIYVKFLGLDREQLSRYTLVIQAADLQGDGMMTTGTAVITVTDSNDNAPQFDETTHIVSVSENQVAAIVAKLPVIDADELGSPAWSTKYRIISGDKGGFFNVSTGPSRLEGVIMTVKPLDYEKTKQCILSVIVENDDKFVGPLPTSTATVTVNVEDVNEPPEFIPKEQIISKPEDLPVGSDVVVYTATDPDTGRLQKITYKISNDPAGWLTVNRETGLIKIRNSMDRES-SYVRDGKYRTTILALDNDDDNPATGTGTLVIKVEDVNDNAPVINEEHIQICNREAT-VLLSITDTDGPPYAAPFSISLLGDTKKNWTAEMNENKTGILLTLNTVLEPDVYNLVLMVYDNNENHKNSSIQASVCDCKGNDIVCG--RIAVMPLHG--ALGILGGFLVLLLLLLLVLLFMRRKHRSIKEPLIPEDYEIRDNIYCYDEEGGGEDDQDFDLSVLHRGLDNRPN-VYRNDICPIFLSAPQYRPRPASSEDISTFVDHNLKTADNDPTAPPYDSLLVFDYEGVGSDAGSLSSLNSSSSENDQDYDFLNEWGPRFKKLADLYGREED-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q90Z37-1", "uniprot_id": "CADH1_DANRE", "id": "Q90Z37-1", "name": "Cadherin-1", "aln": "--------MACVTTVGLGVIFFLFRVFSSGYTHMSICTPG-----FELEEFVFKVHRNHLHSGKRLGKVTFNNCDGRTRTLFQSIDKRFEINTDGTVTLKRQVTLHEGHKVFSVHAWDSSGMKHTASVRVERVPAQVESSSDVDLTKNKRVKRGWIIPPISVSENSKGPFPMRLVQIKS--DYAIETRLAYKITGEGADLDPKGIFTIDRLSGWVSVTQLLDREKKASYKLRAHANGVDADVTEKPMDIIVTVTDQNDNKPVFTQNPFNGNVPEALEKGEVFMTVTATDADDKENTDNADISYVIISQDPPSPKPNMFAINPVSGGISVLEKGLDREQWFRYTLVITATDMNGEGLSTTGTAVITVTDSNDNAPLFEQSSYTASVPENQVGVEVAKLPVTDGDEPESTAWSTKYQIIAGDKGGFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIVVNDDKFVGPLPTSTATVTVNVKDVNEPPEFIPKEKFISRPENLPVGSNLIPFTAIDPDTEKKQNITYRIGNDPSDWLNIT-GSGQIQVKNALDRES-SNVKDGKYKALILALDNDVESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESAPVLLSITDKDLPPFAGPFKVEPQGDTSKNWSVFFNETGHFLNIKPQSQLEQGEYKVVLRVADREGESQENIIQASVCDCKGEAFQCTDKQVAGIPLFG--VLGVLGGILLLLLLALLLLMFLRRKSNSKKEPLLPED-DVRDNIYYYDEEGGGEDDQDFDLSVLHRGLDNRPE-VFRNDVAPTFMPAPQYRPRPANPEEIGTFIDDNLKAADNDPTAPPYDSLLVFDYEGGGSDAGSLSSLNTSSSGNDQDYDFLNEWGPRFKKLADMYGGGED-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: .. : . : : . : . . :* ** * :.*: * **.*..:* * ::*: : : *.*** *** * *:*:: :* : : ****: . * * .** . .. *.* :: : *:****::* *.::.*.* * *. * .* ***** ** * *. : * * **:* *: ** *: :* * * *****: .* *.: *:*::*:* **. **: : *:***** *: .: . *.** *. * :*.* * * *.** :.* *:.**.*..*.::* *. :*:: * * **:* .* * : * *: *. ***:***:.*:*:****.* *:* .:.:. *.:. *. : :** ***. *:*:* * .**:.** : :* : . :***. . *::. *.. :** *.. . *:******:: : *:**:.*: : . * :**:... :*.***.* .* :.**. . *:. * . ..* : :. :. *: . *.: * : *. . : . *:*:****:* . * * * :**..* ** * * :*:::*:* .. ****: : : ***:: *.******:***:*:: *****: **: * ***: * ::.:* ******..::*..*: .***:*:.********:******** ****.*****.:*:* :****::*.***.*******:** ** ", "identical_positions": 297, "similar_positions": 234, "identity": "33.52%" }, { "cls_id": "homologset.agr.RGD:621090", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F6SEU4-1", "uniprot_id": "SYGP1_MOUSE", "id": "F6SEU4-1", "name": "Ras/Rap GTPase-activating protein SynGAP", "aln": "MSRSRASIHRGSIPAMSYAPFRDVRGPPMHRTQYVHSPYDRPGWNPRFCIISGNQ--LLMLDEDEIHPLLIRDRRSESSRNKLLRRTVSVPVEGRPHGE--------------------------------HEYHLGRSRRKSVPGGKQYSMEAAPAAPFRPSQ--GFLSRRLKSSIKRTKSQPKLDRTSSFR-QILPRFRSAD-----HDRARLMQSFKESHSHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEFCFEVTTSS-GTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREHLIFRENTLATKAIEEYMRLIGQKYLKDAIG--EFIRALYESEENCEVDPIKCTAS---SLAEHQANLRMCCELALCKVVNSHCVFPRELKEVFASWRLRCAERGREDIADRLISASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISN---LDTLTNSSSFEGYIDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTALRN-------------------------------------PNIQRQPSRQS-ERTRSQPMVLRGPSAEMQGYMMRDLNSSIDLQSFMARGLNSSMDMARLPSPTKEKPPPPPPGGGKDLFYVSRPPLARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDGPGGRLNSSSVSNLAAVGDLLHSSQASLT--AALGLR-----------------------------PAPAG-RLSQGSGSSITAAGMRLSQMGVTTDG-VPAQQLRIPLSFQNPLFHMAADGPGPPAGHGGSSGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSK----SEDLSSGVPK--PPAASILHSHSYSDEFG---------------------------PSGTDFTRRQLSL--QDSLQHMLSP---PQITIGPQRPAPSGPGGGSGGGSGGG---QPPPLQ-----RGKSQ---QLTVSAAQ----------KPRPSSGNLLQSPEPSYG----------------PARPRQQSLSKEGSIGGSGGSGGGGGGG------------------------------LKPSITKQHSQTPSTLN----PTMPASERTVAWVSNMPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRK----LEEYERRLLSQEEQTSKILMQYQAR------LEQSEKRLRQQQ-------------------VEKDSQIKSIIGRLMLVEEELRRDHPAMAEPLPEPKKRLLDAQERQLPPLGPTNPRVTLAPPWNGLAPPAPPPPPRLQITENGEFRNTADH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PV0-1", "uniprot_id": "SYGP1_HUMAN", "id": "Q96PV0-1", "name": "Ras/Rap GTPase-activating protein SynGAP", "aln": "MSRSRASIHRGSIPAMSYAPFRDVRGPSMHRTQYVHSPYDRPGWNPRFCIISGNQ--LLMLDEDEIHPLLIRDRRSESSRNKLLRRTVSVPVEGRPHGE--------------------------------HEYHLGRSRRKSVPGGKQYSMEGAPAAPFRPSQ--GFLSRRLKSSIKRTKSQPKLDRTSSFR-QILPRFRSAD-----HDRARLMQSFKESHSHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEFCFEVTTSS-GTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREHLIFRENTLATKAIEEYMRLIGQKYLKDAIG--EFIRALYESEENCEVDPIKCTAS---SLAEHQANLRMCCELALCKVVNSHCVFPRELKEVFASWRLRCAERGREDIADRLISASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISN---LDTLTNSSSFEGYIDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTALRN-------------------------------------PNIQRQPSRQS-ERPRPQPVVLRGPSAEMQGYMMRDLNSSIDLQSFMARGLNSSMDMARLPSPTKEKPPPPPPGGGKDLFYVSRPPLARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDGPGGRLNSSSVSNLAAVGDLLHSSQASLT--AALGLR-----------------------------PAPAG-RLSQGSGSSITAAGMRLSQMGVTTDG-VPAQQLRIPLSFQNPLFHMAADGPGPPGGHGGGGGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSK----SEDLSSGVPK--PPAASILHSHSYSDEFG---------------------------PSGTDFTRRQLSL--QDNLQHMLSP---PQITIGPQRPAPSGPGGGSGGGSGGGGGGQPPPLQ-----RGKSQ---QLTVSAAQ----------KPRPSSGNLLQSPEPSYG----------------PARPRQQSLSKEGSIGGSGGSGGGGGGG------------------------------LKPSITKQHSQTPSTLN----PTMPASERTVAWVSNMPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRK----LEEYERRLLSQEEQTSKILMQYQAR------LEQSEKRLRQQQ-------------------AEKDSQIKSIIGRLMLVEEELRRDHPAMAEPLPEPKKRLLDAQERQLPPLGPTNPRVTLAPPWNGLAPPAPPPPPRLQITENGEFRNTADH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QUH6-1", "uniprot_id": "SYGP1_RAT", "id": "Q9QUH6-1", "name": "Ras/Rap GTPase-activating protein SynGAP", "aln": "MSRSRASIHRGSIPAMSYAPFRDVRGPPMHRTQYVHSPYDRPGWNPRFCIISGNQ--LLMLDEDEIHPLLIRDRRSESSRNKLLRRTVSVPVEGRPHGE--------------------------------HEYHLGRSRRKSVPGGKQYSMEAAPAAPFRPSQ--GFLSRRLKSSIKRTKSQPKLDRTSSFR-QILPRFRSAD-----HDRARLMQSFKESHSHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEFCFEVTTSS-GTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREHLIFRENTLATKAIEEYMRLIGQKYLKDAIG--EFIRALYESEENCEVDPIKCTAS---SLAEHQANLRMCCELALCKVVNSHCVFPRELKEVFASWRLRCAERGREDIADRLISASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISN---LDTLTNSSSFEGYIDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLSDISTALRN-------------------------------------PNIQRQPSRQS-ERARSQPMVLRGPSAEMQGYMMRDLNSSIDLQSFMARGLNSSMDMARLPSPTKEKPPPPPPGGGKDLFYVSRPPLARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDGPGGRLNSSSVSNLAAVGDLLHSSQASLT--AALGLR-----------------------------PAPAG-RLSQGSGSSITAAGMRLSQMGVTTDG-VPAQQLRIPLSFQNPLFHMAADGPGPPAGHGGSSGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSK----SEDLSTGVPK--PPAASILHSHSYSDEFG---------------------------PSGTDFTRRQLSL--QDNLQHMLSP---PQITIGPQRPAPSGPGGGSGGGSGGGGGGQPPPLQ-----RGKSQ---QLTVSAAQ----------KPRPSSGNLLQSPEPSYG----------------PARPRQQSLSKEGSIGGSGGSGGGGGGG------------------------------LKPSITKQHSQTPSTLN----PTMPASERTVAWVSNMPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRK----LEEYERRLLSQEEQTSKILMQYQAR------LEQSEKRLRQQQ-------------------VEKDSQIKSIIGRLMLVEEELRRDHPAMAEPLPEPKKRLLDAQRGSFPPWVQQT-RV----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B5U5-1", "uniprot_id": "A0A8M2B5U5_DANRE", "id": "A0A8M2B5U5-1", "name": "", "aln": "--MSYVSSQDGRCVSPCSRPHTPLNG----------HAHDSPGWSRQLRVRDGDQ--FYLLDQEEVHPLLMNDHRPVSHRHKLLRRTVSVPADSRPHPE--------------------------------SEH--ARARRKSFATSRQRSMETPPTAPTQPFRQPSFLSRRLKGSIKRAKSQPKLDRTGSFRHMILPRFRSAD-----QERTRLMQSFKESHSHESLLSPSSAAEALDLTLDEDAIIKPVHSSILGQEYCFEVTTAS-GTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARDLPPKKRYYCELCLDDMLYARTTSKPR---TDTVFWGEHFEFNNLPAIRSLRLHLYKENDKKRRKEKSTYLGLVSIPIPSVTGRQFVEQWYPLIQPS------VLAKGGGGG--------GKIINASLRLKSRFQSMNILPMELYKEFAEYVTNNYRTLCGVLEPLLSAKSKEEVACALVHILQSTGKAKDFLSDMAMCEVDRFMDREHLIFRENTLATKAIEEFLKLIAHRYLKDTIGEGEFIRALYESEENCEVDPMRTPPS---VLADHQANLRMCCELALCKIINSHCVFPRELKEVFASWRVRCAERGREDIADRLISSSLFLRFLCPAIMSPSLFNLTQEYPSERTSRTLTLIAKVVQSLASFSKFSGKEDYLGFMNEFLEMEWGSMQQFLYEISN---LECVSNAGAFEGYIDLGRELSILHSLLWEVMAQLSKDAILKLGPLPRLLNDISVALRN-------------------------------------PQLHRQASHQPPERHLSRPAFSRLATNDFQSLMMRDLNSSIDISRLPSP-TAGLSGSGVLSHPGMAAFSERDPRGNKDVFYVTRPPLARSSPAYCTSSSDITEPDPKVLSVNKSVSMMDLQDS----RIN--SVSNLHSVNDLLNSSQGSLAGFGPLGGA-----------------------------PLRAGGRVSAGSGGSSMSGGLRLTTDSLSQQQQQAAAAMHVPLSFQNPLFHLASDGPQYHTPPHGPTAVPPPLLLAPEPENGHVGFGVP---TFA-HSGFSR----SEDLSALRTQNSLVQPNIVHSHSYSDDFTR--------------------------HNQADYARRQLSLQVQENLQQQVLMGMTPQTATGTGTPASLATPPTTIHPVRQAS-MAPPPPQ-----RAKPQPAHQLSVSSAVNST-----PPKTRPQSGNLLQSPESSFGGRQLTRQQLSVKDSPAPGLPHQSSNASENPAPQSAANESTENTPTNQSAKN--------------TQQSNQQHLLKPSGNKQGSKSPSTLN----PTSAASERTVAWVSNMPHLSADIESLRVDREEFKLKEHSKSMDESRLDRVREYEEEINSLKERLMMSHRK----LEEYERRLHSQEQQTSKILLQYQSR------LDDSERRLRQQQ-------------------VEKDSQIKGIINRLMAVEDELR------GSGMPDLKTRIFTEQ----PIYGAHSGT-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T498-1", "uniprot_id": "GAP2_DROME", "id": "Q8T498-1", "name": "Ras GTPase-activating protein raskol", "aln": "---MGRRTYLSRSSTISYPSRIEGWLDVCETEGELTRLIKTLPWGPLYCVLQQDDQTFTAYCSEEISLGDVCYEDIPRVRLDRVRRPAKALWDGPPTLVEENEDSDSCVGGSGGMSGINDIVLNTTLYSELGEYKSKTLPRIHFDTALNDTSLNEDTSYEKACRRGSAPTTPILGSKQHQTEHNATSRFTNFFSKKSNPLKRTKSVTKLERTKRGSGGLRGSRSHESLLSSHAVMSTIDLSCTGAVGVAPVHQSVLGRRHCFQVRGGPRGERYYSCGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQ---TDLLFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILSDKAGDSLGRTSGGGGSGS------KDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGD-QRLTFRGNSLATKSMEAFLKLTGEQYLQDTLS--APINELIQSERDCEVDPTKTSGSSAGSLQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGRQDMADNLISASIFLRFLCPAILSPSLFNITSELPSARATRNLTLVAKTLQTLANFTRFQGKENFMEFLNDFLEQEAARMQQFLEIISTRPEHPAPDSILDWAGYIDQGKQLSILHSLLSESLAKLPEARQHELDPLQHILDEISRAKEHGMGTALPGGYLPATSSTHSIASENQENRNPGSSGSHAGSNSEQLLPQQSQLAQPQHAIVSKPLSAERGIMRGVLTPNSLEKNIFRYNDPTVNGLLQQQQQQQQQQQQQQQQHQQLQQHGHQQQPHHQHPLQMLSNSQTSIAGNQYMSSPGGLQHAQSQTSMASSSLNGSSSNLLHGHQQHAHHPQQLHPHHCPPAPQTSASSTMERMDRMNYPYMSHNGNDYETSTPSSTRSRTLPRNGNPNANGNVGSSNNNQSGSYDDMHGEFQIQISGFDTSSAFVCKSPTPMMKSSLGPAGAGRSHHKLNLGIPDHSGGYVRGNNLNPNSNMPKNLEDLDDLFKYAEEHDVAEPANHHNHNQGQQNHQGHLKPAAVPGKEQLSAKSSHCSSGYQSISTNPSPSQSSSPVESQLKAAMGSHNAPLAFKNPSYQLQPQTGSSRSSAQSNTHQQQQQQQQQQFGSRLKPIGGGLVAARAAFLNSGGALEAATLTPSSSDEQLSADNYFSYAAAAAAGAGIATKLEAQRSLSGGSSSSTSASASTSNLGKSGGSSAYGRLNGPLKREDVYGSGYGGSSGNVGYGLSTSSAAGHHQHPHQQQQNPMQQQQQRERDQEHKQYAGSVAGSVGSATSAAQRRLSLDSARTLSDSSTDTEGHCNQLQEGKRRRQLRSSGGSGGGGAGSEQGLGKSYDQNGEIQLLQQTLDTLCHTLDRDEAELRDSSDELFGLQRPAGSNGSNNLSLQSESTMRSIIDRLITMEEELRREQLKMSLALS-HKQRVIEEQGQQIAALDAANSRLLSALTALRQRYETQQQQQQHQAPPKTQKPQ----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . *. : . :: : .:*: : . * . :**.... :. * *: * . . : : :: :. : . : : .* :: ..: .* .* :: :. . * .:: *:*******. :. .:::*. : ***.*:**:..**:* .. * : ::* * *** ** .*:::: ** :::**.** **:*: **::*******:*** **. **.**: * : * :******:* ::* :. : :::::: ***::::* ::* *.:*: ::.* *****: . . ***.* .* .::*:*.*:*: .***:::* :* *:.::*: :* .*** :..*.**::. *** :::: * * **:*:. :: *. : ::* ** *:****::* :::* ..:**:*::. *. * :**.:***** : . * * :** ** . . * :.:** ** :*:: **::* * : **:*:**.***:*:*********:*****.: .* *. :::*.***:**.:*.**.*::* .**::: *:*:*** * . ***** **. . : **** *::** **:** * :.:*.: :*.** ::*.:** * .: . .* * : .: . . :. * *... . : . : : : :. * *.*: : . : :* .:. : * . :* * . * . : : .* . . . * : * .*.. ..: : . : . ::: :* :. :....* . . . * .: . .: :** : . *.*. .:: :: : * * :..*: : * .. . * * *. ::. :* . *.*.: *.: :. . . . . :.. . * .. . . *..* : * : ** . ::..: * :. : ::::.:* * . :: .. :.* * *: * .. :*..:* : *: *: .* .**:.. :.:* ::.**.**: :*:*** . :. * *:: * . . ", "identical_positions": 296, "similar_positions": 411, "identity": "18.5%" }, { "cls_id": "homologset.agr.RGD:621091", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63149-1", "uniprot_id": "CADH4_RAT", "id": "Q63149-1", "name": "Cadherin-4", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFNIDSMSGRMYVTRPMDREERASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTTSTFAGEVPENRIETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P39038-1", "uniprot_id": "CADH4_MOUSE", "id": "P39038-1", "name": "Cadherin-4", "aln": "MTTGSVLPLLLLGLSGALRAHREDLTVREACKAGFSEEGYTALISPNVLEGEKLLKVEFSSCVGTKGMQYETNSLDFKVGADGTVFATRELKIPSEQVAFTVTARERQSAEQWAAMVRLLVAQTSSAHSEHK--KGQ-TVALDPSQPPNDTLLPWPQHQSSGGLRRQKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFNIDSMSGRMYVTRPMDREERASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTTSTFAGEVPENRIETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISVTDVNEAPYFPSNHKLIRLEEGVPAGTALTTFSAVDPDRFMQQAVRYSKLSDPANWLHINTSNGQITTAAILDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPQLLPKEAQICERPGLNAINITAADADMDPNIGPYVFELPFIPTTVRKNWTITRLNGDYAQLSLRILYLEAGVYDVPIIVTDSGNPPLSNTSVIKVKVCPCDENGDCTTVGAVAAAGLGTGAIVAILICIVILLIMVLLFVVWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPEAMEHVLSKTPGVRRVDERPVGAEPQYPVRPVVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADMYGGGEED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55283-1", "uniprot_id": "CADH4_HUMAN", "id": "P55283-1", "name": "Cadherin-4", "aln": "MTAGAGVLLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADMYGGGEED", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ********************************************.******************:*********************************************************************************************************************************************************:***********:*****************************************************************: ", "identical_positions": 291, "similar_positions": 5, "identity": "31.77%" }, { "cls_id": "homologset.agr.RGD:621092", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18421-1", "uniprot_id": "PSB1_RAT", "id": "P18421-1", "name": "Proteasome subunit beta type-1", "aln": "MLS-TAAYRDPDRELVMGPQGSAGPVQMRFSPYAFNGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNN-KAMTTGAIAAMLSTILYSRRFFPYYVYNIIEGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNM---QNVEHVP-----LTLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVPLRKD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09061-1", "uniprot_id": "PSB1_MOUSE", "id": "O09061-1", "name": "Proteasome subunit beta type-1", "aln": "MLS-TAAYRDVERELGMGPHGSAGPVQLRFSPYAFNGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNN-KAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNM---QNVEHVP-----LTLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVPLRKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20618-1", "uniprot_id": "PSB1_HUMAN", "id": "P20618-1", "name": "Proteasome subunit beta type-1", "aln": "MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNN-KAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNM---QNVEHVP-----LSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DRF3-1", "uniprot_id": "PSB1_DANRE", "id": "Q6DRF3-1", "name": "Proteasome subunit beta type-1", "aln": "MIS-AQAYGENGK---MKEYHYTGPVEHKFSPYAFNGGTVLAVAGEDFAIVASDTRLSEGYSIHSRDSPKCYKLTDTTVLGCSGFHGDCLTLTKIIEARLKMYKHSNN-KSMTSGAIAAMLSTILYGRRFFPYYVYNIIGGLDEEGRGAVYSFDPVGSYQRDTYKAGGSASAMLQPLLDNQIGFKNM---ENVEHVP-----LTQEKAVQLVKDVFISAAERDVYTGDALKVCIVSKEGIKEEIVPLRKD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40304-1", "uniprot_id": "PSB1_DROME", "id": "P40304-1", "name": "Proteasome subunit beta type-1", "aln": "-MS-RLGFEQ------FPDYQVPGMKHPDFSPYESNGGSIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGSAGCWADTLSLTGSIKVRMQSYEHTHL-RTMTTEAVAQMLSIAMYNRRFFPYYVSNILAGIDNEGKGVVYSYDPIGHCEKATYRAGGTAGTLLQPVLDNQIGHKNMNL-EDADKIK-----LTKERAVSVASDTFISAAERDIYTGDSVLINIITKDGIEVRTLTLRQD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23724-1", "uniprot_id": "PSB6_YEAST", "id": "P23724-1", "name": "Proteasome subunit beta type-6", "aln": "MATIASEYSS---------EASNTPIEHQFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . *.** ***:::.:**:**:::*.*** .:.*::* ..* :. *:.. * .* :*. :: :: *.. : : :: : * :. :*.:******* .*: *:*::*:*.***:**:* :: :***:*.::: *.****:..** :: *: :..: :. * * **:**.: .**.: : *::*:*:. . *::*", "identical_positions": 67, "similar_positions": 90, "identity": "26.8%" }, { "cls_id": "homologset.agr.RGD:621093", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70195-1", "uniprot_id": "PSB7_MOUSE", "id": "P70195-1", "name": "Proteasome subunit beta type-7", "aln": "---------MAAVSVFQPPVGGFSFDNCRRNAVLEADFAKKGFKLPKARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLTTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSNIDLCVISKSK-LDFLRPFSVPNKKGTRLGRYRCEKGTTAVLTEKVTPLEIEVLEETVQTMDTS---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHW0-1", "uniprot_id": "PSB7_RAT", "id": "Q9JHW0-1", "name": "Proteasome subunit beta type-7", "aln": "---------MAAVSVFQAPVGGFSFDNCRRNAVLEADFAKKGFKLPKARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLTTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSNIDLCVISKSK-LDFLRPYSVPNKKGTRFGRYRCEKGTTAVLTEKVTPLELEVLEEIVQTMDTS---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99436-1", "uniprot_id": "PSB7_HUMAN", "id": "Q99436-1", "name": "Proteasome subunit beta type-7", "aln": "---------MAAVSVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNK-LDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMDTS---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25043-1", "uniprot_id": "PSB2_YEAST", "id": "P25043-1", "name": "Proteasome subunit beta type-2", "aln": "-------------------MAGLSFDNYQRNNFLAEN----SHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGTTAVLKESIVN-ICDIQEEQVDITA-----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VUJ1-1", "uniprot_id": "Q9VUJ1_DROME", "id": "Q9VUJ1-1", "name": "Proteasome subunit beta", "aln": "-------MDLDNARDLP--RAGFNFDNCKRNATLLNR----GFKPPTTTKTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAADTEMTTDLISSQLELHRLQTDREVRVVAANTMLKQMLFRYQGHISAALVLGGVDKTGPHIYSIHPHGSSDKLPYATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIASGVFNDLGSGSNIDLCVIRKGS-VEYLRNYELANKKGKRQLDYRFKTGTSTVLHTNIKD--LLVT-ERVQAVPMEIS-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W470-1", "uniprot_id": "Q9W470_DROME", "id": "Q9W470-1", "name": "Proteasome subunit beta", "aln": "MLFPFSARKANTSADFVGLRSGFNFINCRRNAELLSK----GYEPPKAIKTGTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKIHHLQDHIYCCGAGTAADTEMITLTTSAELDLHRLNTERRVPVVCASMMLRRTLFRYQGHIGAALVMGGVDTTGPQLYCIYPCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQLVREAISAGVFNDLGSGSNIDLCVITAKG-AVYLRTDTIASEKGERLGKYGIKPNSTMVTSISVLS--LQVTDERIYAVDDQQPGTSGVQLDSQQADEELPEGSQTKSP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:.* * :** * .. *.. .***:*.*: :::*:::.****:*:* :*:****:*:* : :*:*.********: * .::::** * * * ** * **:: **:***:*.* *::.*** **.:::.*:. **.* * ::***:****:*:* :: *: *:. :*. :** :*::********:*:**: :** .. : : * .:: * .: : * : ", "identical_positions": 96, "similar_positions": 82, "identity": "30.57%" }, { "cls_id": "homologset.agr.RGD:621094", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35912-1", "uniprot_id": "EMP3_MOUSE", "id": "O35912-1", "name": "Epithelial membrane protein 3", "aln": "MSLLLLVVSALHILILVLLFVATLDKSWWTLPDKESLNLWYDCTWNTTTQTWACSNVSENGWLKAVQALMVLSLILCCLSFILFMFQLYTMRRGGLFYATGLCQLCTSAAVFSGALIYAIHTEEILAKHPSGGSFGYCFALAWVAFPLALVSGTVYIHLRKRE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QYW5-1", "uniprot_id": "EMP3_RAT", "id": "Q9QYW5-1", "name": "Epithelial membrane protein 3", "aln": "MSLLLLVVSALHILILVLLFVATLDKSWWTLPEKESLNLWYDCTWNTTAKTWACSNVSENGWLKAVQALMVLSLILCCLSFILFMIQLYTMRRGGLFYATGLCQLCTSAAVFSGALIYAIHAKEILAKHPSGGSFGYCFALAWVAFPLALVSGIIYIHLRKRE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54852-1", "uniprot_id": "EMP3_HUMAN", "id": "P54852-1", "name": "Epithelial membrane protein 3", "aln": "MSLLLLVVSALHILILILLFVATLDKSWWTLPGKESLNLWYDCTWNNDTKTWACSNVSENGWLKAVQVLMVLSLILCCLSFILFMFQLYTMRRGGLFYATGLCQLCTSVAVFTGALIYAIHAEEILEKHPRGGSFGYCFALAWVAFPLALVSGIIYIHLRKRE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************:*************** *************. ::*****************.*****************:**********************.***:********::*** *** ********************** :********", "identical_positions": 147, "similar_positions": 11, "identity": "90.18%" }, { "cls_id": "homologset.agr.RGD:621095", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NXT2-1", "uniprot_id": "H3C_HUMAN", "id": "Q6NXT2-1", "name": "Histone H3.3C", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVK-PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84245-1", "uniprot_id": "H33_RAT", "id": "P84245-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84243-1", "uniprot_id": "H33_HUMAN", "id": "P84243-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PI20-1", "uniprot_id": "H33_DANRE", "id": "Q6PI20-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "C0HL66-1", "uniprot_id": "H33A_DROME", "id": "C0HL66-1", "name": "Histone H3.3A", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C0HL67-1", "uniprot_id": "H33B_DROME", "id": "C0HL67-1", "name": "Histone H3.3B", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P84244-1", "uniprot_id": "H33_MOUSE", "id": "P84244-1", "name": "Histone H3.3", "aln": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61830-1", "uniprot_id": "H3_YEAST", "id": "P61830-1", "name": "Histone H3", "aln": "MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKDIKLARRLRGERS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************:******:*** *** ****:***********:************************:*******:*:*****: *****.*:*****.********* ***:****:****:", "identical_positions": 117, "similar_positions": 14, "identity": "86.03%" }, { "cls_id": "homologset.agr.RGD:621096", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61089-1", "uniprot_id": "UBE2N_MOUSE", "id": "P61089-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61088-1", "uniprot_id": "UBE2N_HUMAN", "id": "P61088-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQX9-1", "uniprot_id": "UBE2N_RAT", "id": "Q9EQX9-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKSNEAQAIETARAWTRLYAMNNI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35128-1", "uniprot_id": "UBE2N_DROME", "id": "P35128-1", "name": "Ubiquitin-conjugating enzyme E2 N", "aln": "MSSLPRRIIKETQRLMQEPVPGINAIPDENNARYFHVIVTGPNDSPFEGGVFKLELFLPEDYPMSAPKVRFITKIYHPNIDRLGRICLDVLKDKWSPALQIRTILLSIQALLSAPNPDDPLANDVAELWKVNEAEAIRNAREWTQKYAVED--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJS5-1", "uniprot_id": "Q9VJS5_DROME", "id": "Q9VJS5-1", "name": "UBC core domain-containing protein", "aln": "MAALTPRIIKETQRLLEDPVPGISATPDECNARYFHVLVTGPKDSPFEGGNFKLELFLPEDYPMKAPKVRFLTKIFHPNIDRVGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAELWKVNERRAIQLARECTLKHAMQN--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52490-1", "uniprot_id": "UBC13_YEAST", "id": "P52490-1", "name": "Ubiquitin-conjugating enzyme E2 13", "aln": "MASLPKRIIKETEKLVSDPVPGITAEPHDDNLRYFQVTIEGPEQSPYEDGIFELELYLPDDYPMEAPKVRFLTKIYHPNIDRLGRICLDVLKTNWSPALQIRTVLLSIQALLASPNPNDPLANDVAEDWIKNEQGAKAKAREWTKLYAKKKPE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.*. ******::*: :*****.* *.: * ***:* : **::**:*.* *:***:**::*** ******:***:***:*::******:** :*********:********::***:********* * ** * ** * :* :. ", "identical_positions": 94, "similar_positions": 34, "identity": "61.44%" }, { "cls_id": "homologset.agr.RGD:621097", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62191-1", "uniprot_id": "PRS4_HUMAN", "id": "P62191-1", "name": "26S proteasome regulatory subunit 4", "aln": "MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62192-1", "uniprot_id": "PRS4_MOUSE", "id": "P62192-1", "name": "26S proteasome regulatory subunit 4", "aln": "MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62193-1", "uniprot_id": "PRS4_RAT", "id": "P62193-1", "name": "26S proteasome regulatory subunit 4", "aln": "MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48601-1", "uniprot_id": "PRS4_DROME", "id": "P48601-1", "name": "26S proteasome regulatory subunit 4", "aln": "MGQNQS-AQGGAGEKKDDKDKKKKYEPPIPTRVGKKKRRAKGPDAAMKLPQVTPHTRCRLKLLKLERIKDYLMMEDEFIRNQERLKPQDEKNEEERSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDQLEPGCSVLLNHKVHAVVGVLSDDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAEDVNLSELIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKESVLYRKKEGTPEGLYL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40327-1", "uniprot_id": "PRS4_YEAST", "id": "P40327-1", "name": "26S proteasome regulatory subunit 4 homolog", "aln": "MGQGVSSGQDK--KKKKGSNQKPKYEPPVQSKFGRKKRKG-GPATAEKLPNIYPSTRCKLKLLRMERIKDHLLLEEEFVSNSEILKPFEKKQEEEKKQLEEIRGNPLSIGTLEEIIDDDHAIVTSPTMPDYYVSILSFVDKELLEPGCSVLLHHKTMSIVGVLQDDADPMVSVMKMDKSPTESYSDIGGLESQIQEIKESVELPLTHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLCRQIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDDRGDVKVIMATNKIETLDPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLSEDVNLETLVTTKDDLSGADIQAMCTEAGLLALRERRMQVTAEDFKQAKERVMKNKVEENLEGLYL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. * .:. **...::* *****: ::.*:**:: ** :* *** : * *:*:****::*****:*::*:**: *.* :** ::*:***:.:::::**.*:*:*.*******:****::.. .::**********: *********:**. :::*** **:**:*:***::*:* *:*:*****:.***************** ****************.**********************:**************:* *::*:** *:************:******************************.***********:****************** * ** .**::*: ****:*.*::**.*. *: :*********:*:******:*******:** ****::** *: .* * . *****", "identical_positions": 303, "similar_positions": 98, "identity": "68.86%" }, { "cls_id": "homologset.agr.RGD:621098", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08654-1", "uniprot_id": "PHAF1_RAT", "id": "O08654-1", "name": "Phagosome assembly factor 1", "aln": "MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLLFDAFNQRLKVIEVYDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGAT--VKRMYIYSGNSLQDTKAPMMPLSCFLGNVYAESVDVIRDGTGPS-GLRLRLLAAGCGPGVLADAKMRVFERAVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENAGG-----------QTEICTTYSKWDSIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLY--GPPRPGAH------LRTAELP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922R1-1", "uniprot_id": "PHAF1_MOUSE", "id": "Q922R1-1", "name": "Phagosome assembly factor 1", "aln": "MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIRNVQVLYSEQSPLSHDLILNLTQDGITLLFDAFNQRLKVIEVCELTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSTEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGAT--VKRMYIYSGNSLQDTKAPVMPLSCFLGNVYAESVDVLRDGTGPS-GLRLRLLAAGCGPGVLADAKMRVFERAVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENAGG-----------QTEICTTYSKWDSIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLY--GPPRPGAH------LRTAELP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BSU1-1", "uniprot_id": "PHAF1_HUMAN", "id": "Q9BSU1-1", "name": "Phagosome assembly factor 1", "aln": "MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVCDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGAT--VKRMYIYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTGPA-GLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENADG-----------QTETCTTYSKWDNIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLY--GPPRPGSH------LRTAELP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VSH9-1", "uniprot_id": "PHAF1_DROME", "id": "Q9VSH9-1", "name": "PHAF1 protein CG7083", "aln": "MLDLEIVPEISLGCDAWEFVLGMHFSQAIAIIQSQVGIIKGVQVLYSDTTPLGVDIIINLPQDGVRLIFDPVSQRLKTIEVFNMKLVKLRYFGVYFNSPEVLPSIEQIEHSFGATHPGVYDAAKQLFALHFRGLSFYFPVDS-----KLHSGYAHGLSSLVFLNGASPVVSKMSLYAGSNVLENRVPSLPLSCYHRQMYLESATVLRTAFGHTKGLKLKLFTEGSGR--ALEPRRQCFTRELLFGDSCEDVATSLGAPNRIFFKSEDKMKIHSSSVNRQAQSKRSDIFFNYFTLGIDVLFDARTQTCKKFILHTNYPGHFNFNMYHRCEFQFLLQADHPSMSDSGHDLVTPTKQEHVNITAYTKWDAISSALAT-SERPVVLHRASSTNTANPFGSTFCYGYQDLIFEVMPNSHIASVTLYNTAPPRQPAHSWQQHKMQDIRLTVA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:*** *** : ***.*** ::**:**:*.: **:.******: :**. *:*:**.***: *:**...****.*** ::. ***:* **:*** : *:****::**********::::*** *:****** * :** * ...:****:** : :**: *.:* :*:*..: :.:.* :****: ::* **. *:* . * : **:*:*:: *.* :.: : * * : *****:** : **:*:::*:**********.* ::*. ** .* ********:*:****.*:. ***:********:***:******:: * .: . .. : *:*:*** *.. *. *:******:**.*.:********:* * :***** *.******** .*** :* :: .*. ", "identical_positions": 225, "similar_positions": 122, "identity": "50.45%" }, { "cls_id": "homologset.agr.RGD:621099", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCL8-1", "uniprot_id": "IPP2_MOUSE", "id": "Q9DCL8-1", "name": "Protein phosphatase inhibitor 2", "aln": "---------------------------------------------------MAASTASHRPIKGILKNKTSAASPPVVPSAEQPRPIVEEELS----------------------------------------KKSQKWDEMNILATYHPADKDYGLMKIDEPNTPYHNMIGDDEDAYSDSEGNEVMTPDILAKKLAAAEGSEPKYRTRE---QESSGEEDNDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEE------MAETADGDSMNVEESSQGSTTSDHLQHKSQSS--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50411-1", "uniprot_id": "IPP2_RAT", "id": "P50411-1", "name": "Protein phosphatase inhibitor 2", "aln": "---------------------------------------------------MAASTASHRPIKGILKNKTSTTSS-VVASAEQPRRTVEEELS----------------------------------------KKSQKWDEMNILATYHPADKDYGLMKIDEPDTPYHNMIGDDEDVCSDSEGNEVMTPEILAKKLAAAEGSEPKFRTRE---QESSGEEDNDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEE------MSETADADSMNIEESNQGSTAGDHLQHKSQSS--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41236-1", "uniprot_id": "IPP2_HUMAN", "id": "P41236-1", "name": "Protein phosphatase inhibitor 2", "aln": "---------------------------------------------------MAASTASHRPIKGILKNKTSTTSS-MVASAEQPRGNVDEELS----------------------------------------KKSQKWDEMNILATYHPADKDYGLMKIDEPSTPYHSMMGDDEDACSDTEATEAMAPDILARKLAAAEGLEPKYRIQE---QESSGEEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEE------MLETADGESMNTEESNQGSTPSDQQQNKLRSS--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NXS1-1", "uniprot_id": "IPP2B_HUMAN", "id": "Q6NXS1-1", "name": "Protein phosphatase inhibitor 2 family member B", "aln": "---------------------------------------------------MAASTASHRPIKGILKNKTSTTSS-MVASAEQPRRSVDEELS----------------------------------------KKSQKWDEINILATYHPADKGYGLMKIDEPSPPYHSMMGDDEDACRDTETTEAMAPDILAKKLAAAEGLEPKYRIQE---QESSGEEDSDLSPEEREKKRQFEMRRKLHYNEGLNIKLARQLISKDLHDDDEDEE------MLETADGESMNTEESNQGSTPSDQQQNKLRSS--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96PQ5-1", "uniprot_id": "IPP2L_HUMAN", "id": "Q96PQ5-1", "name": "Putative protein phosphatase inhibitor 2-like protein 1", "aln": "---------------------------------------------------MAASTASQRPLKGILKDNTSTTSS-MVASAEHPRGSVHEQLS----------------------------------------KKSQKWDEMNILATYRPADKDYGLMKIDEPSTPYHSTMGDDEDACSDTETTEAMATDSLAKNLAAAEGLEPKYQVQE---QESSGEEDSDLSPEEREKKRQFEMRRTLHYNEGLNIKLARQLISKDLHDDDKVEE------MLETAHGESMNTEESNQGSTASDQQQNKSRSS--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8JNP7-1", "uniprot_id": "A8JNP7_DROME", "id": "A8JNP7-1", "name": "", "aln": "MEAVVQAEADDNNASDVQRGVGGALLAVVATQWAAMATPPRARGFAATCAIIIWRTSRFQCLFGYCRRDSRLSSSNSGSSNRNNNHKIYEIINDSQPPDVTQIARMQNNPSPQLPCKGILKTSRSFDKSGASFRKSAKFDELNVMQTFHPADKDYGHMKIDEPKTPYNYTEGFD-------ENRDELDTELLVEKLRIAANTQPSTESIE---DDGSSGDDQPLSEEERQRRREFERRRKAHYREFEAVKLARKLIQEEDDDDDDEDK------GADSRPSGSSQGASSSGRFASSSTKRSSSQADSTTSPSTSAGQNMDLEPSNN------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJE7-1", "uniprot_id": "Q9VJE7_DROME", "id": "Q9VJE7-1", "name": "Protein phosphatase inhibitor 2", "aln": "--------------------------------------------------------MDGDQVKGILKS-----------------GNNSAQFS----------------------------------------LKAAKFDEVNILATFHPAGKDYGHMIIDEPKTPFVFEEDLP----------KELDTNALIEKLRHTSKSEMPAFGIEGDSEESSADEDFPESVEEKVRRMEFERRRKVHYKEFYSVPLARRLIADEFAELTSSEFNIHCEGGMESCEACSENNQLDGEASNLTQTKYSYSESQSEYRISDHSEPEPGFSPSHHCYQKLKAELFSKAEPEELASLTHLHRMPSVNDDEPSREPRVPYPSVVPTQTQNLHEHKSSLKITSEKPTPARICKSNPDNRPGTSKKETR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41818-1", "uniprot_id": "GLC8_YEAST", "id": "P41818-1", "name": "Protein GLC8", "aln": "-----------------------------------------MGGILKNPLALSPEQLAQQDPETLEEFRRQVYENTQKNAKLTSHKRNIPGLD----------------------------------------NTKEEGEIIGTSSTFLPKDT----LSLKHEQDMLAKMTPEERVQWNQRNLAENEITKKQFQDIHIDEPKTPYQGAVDPHGEYYRVDDDEDEDNSDK-KPCQVANDDIDDLSLGEPEFEIKENKQPDFETNDENDE--------DSPEARHKKFEEMRKKHYDVRAIFNKKSREALKDEDEDEDDSTTKEP---------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. . : : :. *: * .. : :.. . . .. ..: : : :* . .:: : :. . :. : . : :: . : . ", "identical_positions": 3, "similar_positions": 43, "identity": "0.72%" }, { "cls_id": "homologset.agr.RGD:621100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K072-1", "uniprot_id": "A0A0G2K072_RAT", "id": "A0A0G2K072-1", "name": "", "aln": "MVPVLKVLLFLTLHLLQDTKSFKVHLNNNGYEGVVIAINPSVPEDERLIPSLKEMVTQASTYLFEASQGRFYFRNVSILVPMTWKSKSEYLMPKRESYDKADVIVANSHLKYGDNPYTLQYGQCGDRGRYIHFTPNFLLTDN-VRNYGPRGRVFVHEWAHLRWGVFDEYNEDRPFYISGKNTIEVTRCSTDIKGSKAVHERQRGSDVTRLCRWDSRTGLYEPKCKFFPDKIQTARASIMFMQNLNSVVEFCTEKTHNTEAPNLQNKICNGRSTWDVIKESADFQQAPPMRG--TEAPPPPTFSLLKSRQRVICLVLDKSGSMDTEDRLIRMNQAAELYLTQIVEKESMVGLVTFDSTAQIQNYLIKITNTGDYKKITGNLPQQAVGGTSICRGLEAGFQAITSSDQSTSGSEIVLLTDGED-DLISSCFEVVKHSGAVIHTIALGPKAARELETLSDMTGGLRFYANKDVNS--LMDAFSGISSASGNLSQQALQLESKAFNIGGGTWINGTVPVDSTIGNDTFFVITWTVQKPEIILRDPKRKKYTTSDFQDNKLNIRSARLQIPGTAETGTWTYSLFNKGVKPQLLTVTVTTRARSPTTQPLMATAHMSQSTAQYPSPMIVYARVSQGFLPVLGANVTAVIESENGSRVTLELWDNGAGADTVKNDGIYTRYFTDYHGNGRYSLKVRVQARKSKARLSLRQKNKSLYIPGYVENGKIILNPPRPEVPEEATEAAVEDFSRLTSGESFTVSGAPPDGGHAHVFPPSKVTDLEAEFKGDHIHLTWTAPGKVLDKGRAHRYVIRMSRHPPGLQD-FNDATLVNTSGLIPKEAGSEETFKFKPASFKIENGTQIYIAILANNEAGLTSKVSNIAQAVNFIPPEHSFSTLSPDISAICLTIWGLTVILNDILN--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QX15-1", "uniprot_id": "CA3A1_MOUSE", "id": "Q9QX15-1", "name": "Calcium-activated chloride channel regulator 3A-1", "aln": "MVPGLQVLLFLTLHLLQNTESSMVHLNSNGYEGVVIAINPSVPEDERLIPSIKEMVTQASTYLFEASQGRVYFRNISILVPMTWKSKPEYLMPKRESYDKADVIVADPHLQHGDDPYTLQYGQCGDRGQYIHFTPNFLLTDN-LRIYGPRGRVFVHEWAHLRWGVFDEYNVDQPFYMSRKNTIEATRCSTRITGTNVVHNCERGNCVTRACRRDSKTRLYEPKCTFIPDKIQTAGASIMFMQNLNSVVEFCTEKNHNAEAPNLQNKMCNRRSTWDVIKTSADFQNAPPMRG--TEAPPPPTFSLLKSRRRVVCLVLDKSGSMDKEDRLIRMNQAAELYLTQIVEKESMVGLVTFDSAAHIQNYLIKITSSSDYQKITANLPQQASGGTSICHGLQAGFQAITSSDQSTSGSEIVLLTDGED-NGIRSCFEAVSRSGAIIHTIALGPSAARELETLSDMTGGLRFYANKDLNS--LIDAFSRISSTSGSVSQQALQLESKAFDVRAGAWINGTVPLDSTVGNDTFFVITWMVKKPEIILQDPKGKKYTTSDFQDDKLNIRSARLQIPGTAETGTWTYSIT--GTKSQLITMTVTTRARSPTMEPLLATAHMSQSTAQYPSRMIVYARVSQGFLPVLGANVTALIEAEHGHQVTLELWDNGAGADTVKNDGIYTRYFTDYHGNGRYSLKVRVQAQRNKTRLSLRQKNKSLYIPGYVENGKIVLNPPRPDVQEEAIEATVEDFNRVTSGGSFTVSGAPPDGDHARVFPPSKVTDLEAEFIGDYIHLTWTAPGKVLDNGRAHRYIIRMSQHPLDLQEDFNNATLVNASSLIPKEAGSKETFKFKPETFKIANGIQLYIAIQADNEASLTSEVSNIAQAVKLTSLEDSISALGDDISAISMTIWGLTVIFNSILN--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3APN3-1", "uniprot_id": "A0A8M3APN3_DANRE", "id": "A0A8M3APN3-1", "name": "", "aln": "---MHLRSVFVLLWMLRLSTSTGIKLDGNGYIDITIAISSKVPEDDKLIDKIKDMVTEGSVHLYKALDKKVYFKEVTILVPLNWNSKG-FTKARTELFETGMIRIDNPHPAYGDEPYTNQYGECGAEGQYIHFTPNFLRDDKLIRLYGSRGKVLVHEWAHLRWGVYDEYSEKTPFYRSASGKIEATRCSKNIEG----QLYDVTADPLQPCQNDPQTSLPTDGCRFIPNKYQSTDSSMMSLPSLDSVITFCRESEHNYEAPNLQNAKCSNKATWTVIFEDSVDKDALRSLKPMASTPPAPNFKVVQRMQRTVCLVLDVSGSMK-GSRILRLQQASAHFLQNIIEDQSSVALVTFSTDASTLSALTTIDKESTRENLVKLLPNVAEGATNMCKGLNLGLQVLKTDNQDVLGDEIIFLTDGEATDTLSNCVPAAINSGAIIHTIALGDKADKALREMADKTGGKFITASDDVLSNQLLNGFSSLIMPTGNQTKDPVQIDS--VGIKTSDWFNGTVSVDQTIGTKTSFTITYETKLPRISIQSPSGLTYSQTQMRHDEP-AKTVTLKVPGTAQTGDWKYSILS--PTLQSLTVTATSQAARANVPPITVKAQMNQQFSDGSKPMIVFAEVVQNYKPLIKAEVWATLESESGTVHELQLLDNGAGADTFKDDGVYSRYFTRMK-KGRSSLKVRVKNKDGQARFTLQKRGGAPYVPGYVVNGVVELNPPKLSVSEELPEVG--SFTRTATGESFEVS---LTSSKPPKFPPCKIIDLSAEIQEDAVLLSWTAPGEDLDEGSAKSYDIRWSFEVKDLLFNFSNAHVVNTSVISPQVFGSVEQHLFN-LSFPIQNGTILFFAIQSEDNEKLKSEMSNVASGLQIIPNPN-TGDLDLKLIFIAISVCLASVVVIGIFGITTWALTRKKLSDS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: * :*: : * ::*:.*** .:.***...****::** .:*:***:.*.:*::* : :.**::::****:.*:** : .: * ::.. : : :.* :**:*** ***:** .*:********* *: :* **.**:*:***********:***. . *** * ...**.****. * * : : : *: *.:* * * *:*:* *:: :*:* : .*:**: ** *. ** ******* *. ::** ** .: ::* :.:**.*.*.::: :*.:***** ****. .*::*::**: :* :*:*.:* *.****.: * . * .* . . :::. **: * *.*.:*:**: *:*.:.:.:*.. *.**::***** : : .*. .. .***:******* .* : *. ::* *** : *..*: * *::.** : .:*. :::.:*::* ..: . *:****.:*.*:*..* *.**: .: *.* ::.*. .*: ::::.:: ::. *::****:** *.**: . * :*:*.*::* .. *: ..*:*.*. :: .. ***:*.* *.: *:: *:* * :*:* * *:* ********.*:**:*:**** : :** ******: : .::*::*:::. : *:**** ** : ****: .* ** *. .*.* ::* ** ** ..:. ***.*: **.**: * : *:*****: **:* *: * ** * . .* *.:* :**:* : *: ** * . *: :* * ** :::** :::: *.*::**:*..::: . . . *. .: *.::: :*:. .*:. ", "identical_positions": 342, "similar_positions": 321, "identity": "37.01%" }, { "cls_id": "homologset.agr.RGD:621101", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61244-1", "uniprot_id": "MAX_HUMAN", "id": "P61244-1", "name": "Protein max", "aln": "--MSDND-DIEVESDEE--------QPRFQSAA-----DKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEK-----ASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P28574-1", "uniprot_id": "MAX_MOUSE", "id": "P28574-1", "name": "Protein max", "aln": "--MSDND-DIEVESDEE--------QPRFQSAA-----DKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEK-----ASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGGTISAFDGGSDSSSESEPEEPQSRKKLRMEAS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52164-1", "uniprot_id": "MAX_RAT", "id": "P52164-1", "name": "Protein max", "aln": "--MSDND-DIEVESDEE--------QPRFQSAA-----DKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEK-----ASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGGTISAFDGGSDSSSESEPEEPQNRKKLRMEAS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P52161-1", "uniprot_id": "MAX_DANRE", "id": "P52161-1", "name": "Protein max", "aln": "--MSDND-DIEVDSDAD--------SPRFHGVA-----DKRAHHNALERKRRDHIKDSFHSLRDSVPALQGEKQSIKQASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKVKGTTQLQANYSSSDSSLYTNPKGQAVSAFDGGSDSSSGSEPEEQRTRKKHRPEDS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P91664-1", "uniprot_id": "MAX_DROME", "id": "P91664-1", "name": "Protein max", "aln": "MSMSDDDRDIDIESDEDGDSDTGLGSSRHTNTANFTQAEKRAHHNALERRRRDHIKESFTNLREAVPTLKGEK-----ASRAQILKKTTECIQTMRRKISENQKDIEEIKRQNNIIAKQIQALE-------------SSNGDQFS----EFLSDEEVGSEEADDEDLDQDFSRRNKKMKTFHA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:* **:::** : ..*. ..* :**********:******:** .**::**:*:*** *******.*:** ** **** :*:**:::**** :: :*::*** **:.. :: :* : **:.:. .: :: .*:: : : ", "identical_positions": 69, "similar_positions": 50, "identity": "37.7%" }, { "cls_id": "homologset.agr.RGD:621102", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63570-1", "uniprot_id": "PRS6B_RAT", "id": "Q63570-1", "name": "26S proteasome regulatory subunit 6B", "aln": "-ME-EIGILVEKIQDEIPALS-----VSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFP-LPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKD--EQEHEFYK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54775-1", "uniprot_id": "PRS6B_MOUSE", "id": "P54775-1", "name": "26S proteasome regulatory subunit 6B", "aln": "-ME-EIGILVEKIQDEIPALS-----VSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFP-LPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKD--EQEHEFYK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43686-1", "uniprot_id": "PRS6B_HUMAN", "id": "P43686-1", "name": "26S proteasome regulatory subunit 6B", "aln": "-ME-EIGILVEKAQDEIPALS-----VSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFP-LPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKD--EQEHEFYK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R1D0-1", "uniprot_id": "B0R1D0_DANRE", "id": "B0R1D0-1", "name": "26S proteasome regulatory subunit 6B", "aln": "-ME-DGGVLVEKPQDDVPALL-----NSRPQTGLSFLAPEPEDLEDLYSIYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVLYSDIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFP-LPDRRQKRLVFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQEAGMLAVRENRYIVLAKDFEKAYKTVIKKD--EQEHEFYK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V405-1", "uniprot_id": "Q9V405_DROME", "id": "Q9V405-1", "name": "26S proteasome regulatory subunit 6B", "aln": "-MPYNMDVLIPE-KDELSDLK-----LKDAHSSLDEL-----DMEDLYVRYKKLQKTLEFIEVQEEYIKDEQRNLKKEYLHAQEEVKRIQSVPLVIGQFLEAVDQNTGIVGSTTGSNYYVRILSTIDRELLKPSASVALHKHSNALVDVLPPEADSSISMLQPDEKPDVSYADIGGMDMQKQEIREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTTNVKVIMATNRADTLDPALLRPGRLDRKIEFP-LPDRRQKRLVFSTITSKMNLSEDVDLEEFVARPDKISGADINAICQEAGMHAVRENRYIVLAKDFEKGYKNNIKKD--EQEHEFYK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VH79-1", "uniprot_id": "Q9VH79_DROME", "id": "Q9VH79-1", "name": "26S proteasome regulatory subunit 6B", "aln": "-MR-----LLKEEIAQFHEQS-----LEKYDG---------LDPHDLYVLYKKLQMELELIQVQEDYIKEEQRNLKKEFIHAQEEVKRIKAVPLVIGQFLEAVDENNGIVASTTGSNYYVRVLSTIDREQLKPSSSVGLHKQSNCLVDLVPPEADSTISMLSPDEKPDISYSDIGGLDIQKQEIREAVELPLTHAQLYKQIGIDPPRGVLLFGPPGCGKTMLAKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVRDLFRLAKQNSPSIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDETTNIKVIMATNRADTLDPALLRPGRLDRKIELP-LPDRRQKRLVFTTITSKMNVGEDVDLEDIIARPDKISNADINAICQEAGMHAVRENRYVVNAKDFEKGYKTSVRKD--EAQHEFYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33298-1", "uniprot_id": "PRS6B_YEAST", "id": "P33298-1", "name": "26S proteasome regulatory subunit 6B homolog", "aln": "MEELGIVTPVEKAVEEKPAVKSYASLLAQLNGTVNNNSALSNVNSDIYFKLKKLEKEYELLTLQEDYIKDEQRHLKRELKRAQEEVKRIQSVPLVIGQFLEPIDQNTGIVSSTTGMSYVVRILSTLDRELLKPSMSVALHRHSNALVDILPPDSDSSISVMGENEKPDVTYADVGGLDMQKQEIREAVELPLVQADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAAFIRVNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDAQTGSDREVQRILIELLTQMDGFDQSTNVKVIMATNRADTLDPALLRPGRLDRKIEFPSLRDRRERRLIFGTIASKMSLAPEADLDSLIIRNDSLSGAVIAAIMQEAGLRAVRKNRYVILQSDLEEAYATQVKTDNTVDKFDFYK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . *:* ***: *:: :**:***:**::**:* :********:::*********.:*:*..**.**** .* **:***:*** ***. **.**::**.***::**::**:* :: ::***: *:*:**:*:****:********.: :**:***********::**** *****.****: *.*:**** *****:************:****::*:*:******:*:***********:********:***.******:..*:***************************:* * ***::**:* **:***.:. :.**:. : * *.:*.* * :* **:*: ***:***:: .*:*:.* . ::.* :.:**.", "identical_positions": 241, "similar_positions": 106, "identity": "56.31%" }, { "cls_id": "homologset.agr.RGD:621103", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41223-1", "uniprot_id": "BUD31_HUMAN", "id": "P41223-1", "name": "Protein BUD31 homolog", "aln": "MPKVKRSR-KAPPDGWELIEPTLDELDQKMREAETEPHE--GKRKVESLWPIFRIHHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKSKLEVGR--------IIECTHCGCRGCSG--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PGH1-1", "uniprot_id": "BUD31_MOUSE", "id": "Q6PGH1-1", "name": "Protein BUD31 homolog", "aln": "MPKVKRSR-KAPPDGWELIEPTLDELDQKMREAETEPHE--GKRKVESLWPIFRIHHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKSKLEVGR--------IIECTHCGCRGCSG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70454-1", "uniprot_id": "BUD31_RAT", "id": "O70454-1", "name": "Protein BUD31 homolog", "aln": "MPKVKRSR-KAPPDGWELIEPTLDELDQKMREAETEPHE--GKRKVESLWPIFRIHHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKSKLEVGR--------IIECTHCGCRGCSG--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q567Z7-1", "uniprot_id": "BUD31_DANRE", "id": "Q567Z7-1", "name": "Protein BUD31 homolog", "aln": "MPKVKRSR-KPPPDGWELVEPTLDELDQKMREAETEPHE--GKRKVESLWPIFRLHHQRSRYIFDLFYKRKAISRELYKYCIRGGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKGKLEVGR--------IIECTHCGCRGCSG--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O97454-1", "uniprot_id": "O97454_DROME", "id": "O97454-1", "name": "Protein BUD31 homolog", "aln": "MPKVRRSR-KPPPDGWELIEPTLEELEQKMREAETEPHE--GKRITESLWPIFKIHHQKTRYIYDLFYRRKAISRELYDYCLKEKIADGNLIAKWKKSGYENLCCLRCIQTRDTNFGTNCICRVPKCKLEEGR--------IVECVHCGCRGCSG--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25337-1", "uniprot_id": "BUD31_YEAST", "id": "P25337-1", "name": "Pre-mRNA-splicing factor BUD31", "aln": "MPRIKTRRSKPAPDGFEKIKPTLTDFEIQLRDAQKDKSSKLAAKSNEQLWEIMQLHHQRSRYIYTLYYKRKAISKDLYDWLIKEKYADKLLIAKWRKTGYEKLCCLRCIQKNETNNGSTCICRVPRAQLEEEARKKGTQVSFHQCVHCGCRGCASTD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::: * *..***:* ::*** ::: ::*:*:.: . . : *.** *:::***::***: *:*:*****::**.: :: ** *****:* ***:********..:** *:.******: :** : :*.*******:. ", "identical_positions": 70, "similar_positions": 49, "identity": "44.59%" }, { "cls_id": "homologset.agr.RGD:621104", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VFG1-1", "uniprot_id": "Q9VFG1_DROME", "id": "Q9VFG1-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-------------------------------------------------------------------------------------------MAMDFDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVP-DHWCYHEQLENRSYAEI------------------AAIYAPF-KRPSCTRLASINMDGSNATASS----EPCNRWIYHYD-HGFISMNADLNWVCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSATIFAETLLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGLGMICASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVSEADYELFRQHCKTKESEA----RSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSI-SPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTG-ILLA-FWTQHSATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLD-TYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGEEFGKGERMFDFMRSFKKADQHDLSADTIEKLMGDKRTY---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFG2-1", "uniprot_id": "Q9VFG2_DROME", "id": "Q9VFG2-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFEEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFVP-DHWCYHEQLENRSFAEI------------------EKIYSQF-EKPSCTRLEKIDEDGQNHTLSR----ERCNRWIYKYD-FGYKSMNTELNWVCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILANWCGFLGDFSTIFAGSLTSFSISRFISGLAADANSYLMYILILEYVSPSLRNVGLNTVLGSFYCLGLIGACWLAVWVGHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAKINRRQVADKDFKDFRIYCEQHYRKD----KNQE---EHAKLLDMLKTPRMRSTAFKLLLIFIIIVPCYNTIARNVEGLGI-SPFIMFSLNALTLPPSGYLQGLLQDRMGRKATAVGWMAITGIFAVAAG-LVIS-QGSNRNVLLLVGLTMAARFGVSIADGASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPYILHLG-TYYKPAPSIILGLLFLSGAYVCLLLPETRNKKLPMSLAEGEEFGRGEGIFDFLRHMFRREGSKSEVEMGPTIVEEDTLINKPV-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFG0-1", "uniprot_id": "Q9VFG0_DROME", "id": "Q9VFG0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVP-QHWCYHEALENRSFEEI------------------AAIYAPFGKEASCTRLDKIE--GDRVTVSN----ETCQRWIYNYD-FGFRSMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLAGNWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKLS----NQPE---QTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGL-SPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALG-VALSTEGAQKNVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLG-TKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGEAFGKGESMLSFDCWRRHDDDVSKEATEEVRLHQLNGQTKSETEAEV-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV5-1", "uniprot_id": "Q9VDV5_DROME", "id": "Q9VDV5-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVP-DHWCYHDKLVNMTYKEI------------------GEIYAQF-ENPSCTRLDDIN--GHNVTVSS----KACEKWIYNYD-FGYRSMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKSVATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQMTHEML----GGDD--KKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGI-SPFIMFSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAG-IAIAYQQHNHNAILLACLTIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLG-TFFKAAPSIILGVLFFAGSFVCLLLPETLNRSLPTTIEEGEVFGKGERMFDFPCLHNKHDDEESESELEKYKRKHSLIDAKQMQMESCSNGKRKQSLIDADHEEQALKDANH------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV9-1", "uniprot_id": "Q9VDV9_DROME", "id": "Q9VDV9-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------MLEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVP-KYWCADGLP--------------------------ASIESPV--DSSCLPL-------NRNISTP----NTCYSYNYELY-MGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKCSQQNQ----KASP------HLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGI-SPFVMFSLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTR-SVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTSLEDGENFGKNDRWYTFSFLEGRTQSAATLDTQNAKMYSQSTESAVYF-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV8-1", "uniprot_id": "Q9VDV8_DROME", "id": "Q9VDV8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDLQSVLEKCGNFGPYQILLLGLFGYTNIVSSLHYFSQTIISFTP-SHRCSRP--------------------------------EDYQPNSTSLLSCSVMQFDKEF---------KCTSWDFERE-SNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRFISGLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLPALGMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLN------NSQNK--SSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGI-SPFKLFSYSGFCYLPAGLTIILFQNKIGRKGMACASLFVGAIITAATG-YLVATLDPSDYSVLLGFMVSLGRYGAVVAYDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLG-TFYKPLPSLMISFILLIGACLCLALPETLHKNLPQNLEEGEMFAKGEKWYFFPCFSRRPKTQKSATQLESSDGITNKL----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV7-1", "uniprot_id": "Q9VDV7_DROME", "id": "Q9VDV7-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDLQRVLEKCGNFGPYQILLLGLYGYTNIVSSLHYFSQTLISFTP-SHRCSAPV-------------------------------EEFSQNFTELLSCSVIQYDVDMTSFRD---NKCSSWDFDKE-SNYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPMFSFTRFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYSIGLMISPWIAIWLGNWRSYLWAASLPALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVEDSVFDEFIKHYREKLN------SAQKK--SSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGI-SPFKLFSYSGFVVLPGGLSIILFQNKIGRKGMACASLLVGAFITATTG-YLVGTLDPANYSVLLGFMVCLARFGAVVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYLG-TFYKPLPSLLISFLLIIGACLCLTLPETLHKQLPQTLEEGEIFAKGEKWYFFPCFSRKRQSNKSESQLESANEITK------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDW0-1", "uniprot_id": "Q9VDW0_DROME", "id": "Q9VDW0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTP-EHWCFHADLNGLSVEGI------------------RSVYENISASSCTPLLGVVNGTGVVSTN------RKCRNWIFNRE-SGYESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYRERELQD----YKLNS--HEDTFLAMFLTPRLRRFTLTLLVKSVIITLSCDVINRNMEGLGT-SPFKLFSFTSIVYLPAGVAILLLQNKIGRKGMACTALFVGGLITTATG-FMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASSSLAFYVIYLA-QYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEKFALNESFLYFPCFS-RKEKNVRTESV--------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDV6-1", "uniprot_id": "Q9VDV6_DROME", "id": "Q9VDV6-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDFDRVLEKCGNFGRFQFVILILYGYTNILSSLHYFSQTLITFTP-EHWCSHDDLMGLGAAEL------------------RSIYSNVSHPSCTLLSEVINGTGVASE-------ESCQDWIFERE-NGYESLTTELKWVCDKSHQPAVGQSFFFLGSVVGTISFGFLSDHIGRLPAMLMAALSGATGDFITSFVHTLPWFAFSRFVSGLSTDTMYYLMYILVFEYLSPKRRTFGLNIILAVFYCFGLMTSPWIAMWIGNWRRYLWLASLPALGVLIYPLLICESAQWLLTKKKYDEAVACLKKVAKFNGRQVEDSVFDEFVKHYREKMNEE----SKLNK--QMDTFLGMFKTPRLRRFTTTLLVKSVIITLSYDVINRNMEGLGS-SPFKLFSLTSSVYLPAGFTILLLQNKIGRKGMACGALLVGAIITAVTG-FLIAVLDPSENAVLLALMVGLGRFGTTVSYDAEIQYAAEIIPTSVRGQAVSNIHVVGLASSSLAFYVIYLA-QYYKPLPSIFISVLMFLGALLCLTLPETLHKKLPETLADGERFAMNESCLYFPCLHKRRESLTEHEDRKSEP----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IVM8-1", "uniprot_id": "S22A9_HUMAN", "id": "Q8IVM8-1", "name": "Organic anion transporter 7", "aln": "---------------------------------------------------------------------------------------------MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIP-GHRCWVHILDNDTVSDNDTGALSQDALLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGWVYDRI-SFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGMCPS-GIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELE----AAQKKKP---SLCEMLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGN-NVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAICLLAII------FVPQEMQTLREVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFANIAGALAPLMMILS-VYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQDEKNERKDP-----------REPKQEDPRVEVTQF---------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6T423-1", "uniprot_id": "S22AP_HUMAN", "id": "Q6T423-1", "name": "Solute carrier family 22 member 25", "aln": "---------------------------------------------------------------------------------------------MAFQDLLDQVGGLGRFQILQMVFLIMFNVIVYHQTQLENFAAFIL-DHRCWVHILDNDTIPDNDPGTLSQDALLRISIPFDSNLRPEKCRRFVHPQWKLIHLNGTFPNTSEPDTEPCVDGWVYDQS-SFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRFGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTLTLCAA-SIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEGLKELRKAAHRNGMKNAEDILTMEVLKSTMKQELE----AAQKKH----SLCELLRIPNICKRICFLSFVRFASTIPFWGLTLHLQHLGN-NVFLLQTLFGAVTLLANCVAPWALNHMSRRLSQMLLMFLLATCLLAII------FVPQEMQTLRVVLATLGVGAASLGITCSTAQENELIPSIIRGRATGITGNFANIGGALASLMMILS-IYSRPLPWIIYGVFAILSGLVVLLLPETRNQPLLDSIQDVENEGVNS-----------LAAPQRSSVL--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63ZE4-1", "uniprot_id": "S22AA_HUMAN", "id": "Q63ZE4-1", "name": "Solute carrier family 22 member 10", "aln": "---------------------------------------------------------------------------------------------MAFEELLSQVGGLGRFQMLHLVFILPSLMLLIPHILLENFAAAIP-GHRCWVHMLDNNTGSGNETGILSEDALLRISIPLDSNLRPEKCRRFVHPQWQLLHLNGTIHSTSEADTEPCVDGWVYDQS-YFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWCLLQLAITDTCAAFAPTFPVYCVLRFLAGFSSMIIISNNSLPITEWIRPNSKALVVILSSGAL-SIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALRKVARTNGIKNAEETLNIEVVRSTMQEELD----AAQTKT----TVCDLFRNPSMRKRICILVFLRFANTIPFYGTMVNLQHVGS-NIFLLQVLYGAVALIVRCLALLTLNHMGRRISQILFMFLVGLSILANT------FVPKEMQTLRVALACLGIGCSAATFSSVAVHFIELIPTVLRARASGIDLTASRIGAALAPLLMTLT-VFFTTLPWIIYGIFPIIGGLIVFLLPETKNLPLPDTIKDVENQKKNL-----------KEKA--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70609-1", "uniprot_id": "O70609_RAT", "id": "O70609-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MAFQDLLNQVGSLGRFQILQMTFILIFNIIISPHSLLENFTAVIP-NHRCWVPILDNDTVSGNDNGNLSQDDLLRVSIPLDSDLRPEKCRRFVQPQWDLLHLNGTFSSVTEPDTEPCVDGWVYDQS-TFLSTIITEWDLVCESQSLDSIAKFLFLTGILVGNILYGPLTDRFGRRLILICASLQMAVTETCAAFAPTFLIYCSLRFLAGISFSTVLTNSALLIIEWTRPKFQALATGLLLCAG-AIGQTVLAGLAFTVRNWHHLHLAMSVPIFFLLVPTRWLSESARWLIMTNKLQKGLKELIKVAHINGMKNSTDVLTIEVVRTIMKEELE----ASQTKS----SLWDLFRTPNLRKRICLLSLVRFVVWLSVIGLLINFQHLRI-NVFLLQCLLGIITIPANLVGIFLVNHLGRRISQLFIISLFGISILAII------FVPQEMQILRMVLATFGGVFSFVSVSSALVHANELLPTIIRATALGVIGIAGSTGAALSPLFMILR-TYSDSLPWIIYGVLSFLGGLVVLLLPETKNQPLPDSIQDVENEGRAS-----------RQGKQNDTLIKVTQF---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VRR0-1", "uniprot_id": "Q9VRR0_DROME", "id": "Q9VRR0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MANDEKGNASTEDDDKPKKREHRDQGQQSKLKKIKYYIEPDKVDIGIQAGDSLEKVKVTYVEPDDEESSHGFFWGKKKSETSLPRRSWETDDYIDFDDLLPMIGQFGRFQIRLFLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPELLHTPVELRKELSIPKE---------KDGSYSRCRMYNTNYTKIHFAENPSAYINTSLPTIPCKKGYVFEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFEASCTQFYKEE----LDGRD----FTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLDSENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGA--------SFQNRANMRMSALAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLS-KKSLSSTLIVLGALGIFGGLLALFLPETLNHELPETLSDGAQFGKNQRIWHMPCCGPGSRKSHPRHNWHQGSSLRTLSKDEFRSSKMYRKTKYRFESHPSPSSSDYKGTEEKEIRTYKYGNGSKWPEDKS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCA0-1", "uniprot_id": "Q9VCA0_DROME", "id": "Q9VCA0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "------------------------------------------------------------------------MTQSTENPEKNRELISEESMKDLLTKQLEVVGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWTHAQKREIVAKG----LDSGGCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMS-IAFSASYPVGMIILAIVGYVIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQVASDKKSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSV-SRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVL------AVPAGSTTWIVAFAMLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCVLVAGLLTLTLPETGTGKLSDKVESSAS----------------STPTEPAEKQ--------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * : . . * . : . * : : * * * . * ** : * * : * . : . : ** .**: : * . : . : . : .*: . *: *: :: . . . : .: . . : .. : *.** * .: . ", "identical_positions": 25, "similar_positions": 48, "identity": "3.42%" }, { "cls_id": "homologset.agr.RGD:621105", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VQI0-1", "uniprot_id": "Q9VQI0_DROME", "id": "Q9VQI0-1", "name": "N-acetylgalactosaminide beta-1,3-galactosyltransferase", "aln": "-------------MERKECVFLDRSNHSQPNTTSPSTARPVLFLLLGIGIGYLITKVLVWPIMDLKSH-----TNRTG-------------ASTSLDIDLTDEVRVLCYVYTKPINHKTQAQAVLETWGRRCNKLIFFSSRSDLNLTGSVELPVSPYFRESWLKTKMALKYLHDHHLNDADWFLEADDETYVVMENLRYMVYPYSPQLAIYFGS------------------PGTVMSRAALRRLVELSLPNPSKCEQKNAGPTAEKLRECLENVNVLAGNTYDSEGRRRMYLIEPQARSNLFLHYDSNIWFWKFLAYRTQDGIFAWSNYAVSFHYVQHRYIHCFEYMIYRLRTFGRKQIVES------------LPPKYNPAAEKDQGAP------------------RIGSDQDVPADYEY-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0L4-1", "uniprot_id": "Q9W0L4_DROME", "id": "Q9W0L4-1", "name": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1", "aln": "------------MYRNILCLVLG------LIIGIQLTDFLEYFQLTDS-------QFASTSITQLEEG-----ASQLA-------------TEEELALWLHNETRVLCMVLTLPKNHQSRVRRVKGTWGRRCNKLIFISSQEDRELG-VIDVGVPEDRNNLYLKMRKALEYVYRNHGEDYDWFLKADDDTFVIMENLRFLLYPYDPEAALYFGHRFRTT----FPQGYMSGGAGYVMSRDALRRLNLFAFNNSQFCPINNN-SEDRQIGFCLQNVGVVAGDSRDEEGRDRFLPLS---LKFMLPTFPTDNWLPKLTFYEPVN--ETGSTSGISFHYVKIHEFEMYEYLLYRLHIFGTPLSQRT------------LPPRLGPDELQNQLNQ------------------WAQENSTNSNAWLKQE-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWM1-1", "uniprot_id": "Q9VWM1_DROME", "id": "Q9VWM1-1", "name": "N-acetylgalactosaminide beta-1,3-galactosyltransferase", "aln": "MAGEYIILENSSTYPGFHSSSNGLANGMYRSAQRISTDRLVLLILLVS--TTVIGLFAYWDVMVLNAG-----ALPLSRGTSSVDYMEPGLRNETLAEKMHREVRVLCWVLTTPKYHKTRAIHVLRTWGKRCNKIYFMTSEPDDELP-TVVLTKPDRYEMLWGKTKEAFVHIHEQMRHEADWFIKADDDTYLFLENLRYMLYPYSPETPIYFGFNYKMVGTHQKNESYMSGGSGYVLSREALR-IFAEGVNDTTKCRQEDDHAEDVEMGKCLFNLGVKAGDSRDEQLRNRFYPIAP-YGALLSGNVGMDFWLYKYAYYNPRSCMDCLSEYPVAFHYVHSKQLYVYDYFNYQFQLSGRAQVAER------------LPKKIREEE-------------------------LVIPESDNPVS----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9JJ05-1", "uniprot_id": "C1GLT_RAT", "id": "Q9JJ05-1", "name": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1", "aln": "--------------MASKSWLNFLT-FLCGSAIGFFLCSQLLNILLQEQADVQPNMLHNDPHARHSDD--SGHNHLKGQMDFNADSSQHKDENTDVAENLYQKVKVLCWVMTSPQNLEKKAKHVKATWAQRCNKVLFMSSEENKDFP-TVGLETKEGREQLYWKTIKAFQYVHDHYLEDADWFMKADDDTYVILDNLRWLLSKYNPEQPIYFGRRFKPY----VKQGYMSGGAGYVLSKEALRRFVDAFK--TEKCTHSSS-IEDLALGRCMEIIKVEAGDSRDPTGKETFHPFVP-EHHLIKGYLPKTFWYWNYNYYPPVEGPGCCSDIAVSFHYVDSTTMYELEYLVYHLRPYGYLYRYQP-----------ALPENILKEINQVNKKE------------------DTKIKLGNP------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJ06-1", "uniprot_id": "C1GLT_MOUSE", "id": "Q9JJ06-1", "name": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1", "aln": "--------------MASKSWLNFLV-FLCGSAIGFFLCSQLLSILLREEAAIQPNMLHNDPHARHSDD--NGHSHLKGQMNFNADSSQHKDENIDVAENLYQKVKILCWVMTSPQNLEKKAKHVKATWAQRCNKVLFMSSEENQDFP-TVGLKTKEGREQLYWKTIKAFQYVHDHYLEDADWFMKADDDTYVIVDNLRWLLSKYNPEQPIYFGRRFKPY----VKQGYMSGGAGYVLSKEALRRFVNAFK--TEKCTHSSS-IEDLALGRCMEIINVEAGDSRDTIGKETFHPFVP-EHHLIKGYLPKTFWYWNYNYYPPIEGPGCCSDIAVSFHYVDGTTMYELEYLVYHLRPYGYLYRYQP-----------ALPENILKEINQVNRKE------------------DTKIKLGNP------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS00-1", "uniprot_id": "C1GLT_HUMAN", "id": "Q9NS00-1", "name": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1", "aln": "--------------MASKSWLNFLT-FLCGSAIGFLLCSQLFSILLGEKVDTQPNVLHNDPHARHSDD--NGQNHLEGQMNFNADSSQHKDENTDIAENLYQKVRILCWVMTGPQNLEKKAKHVKATWAQRCNKVLFMSSEENKDFP-AVGLKTKEGRDQLYWKTIKAFQYVHEHYLEDADWFLKADDDTYVILDNLRWLLSKYDPEEPIYFGRRFKPY----VKQGYMSGGAGYVLSKEALKRFVDAFK--TDKCTHSSS-IEDLALGRCMEIMNVEAGDSRDTIGKETFHPFVP-EHHLIKGYLPRTFWYWNYNYYPPVEGPGCCSDLAVSFHYVDSTTMYELEYLVYHLRPYGYLYRYQP-----------TLPERILKEISQANKNE------------------DTKVKLGNP------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SYI5-1", "uniprot_id": "C1GTB_DANRE", "id": "Q7SYI5-1", "name": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-B", "aln": "-------------MKALGARSAFYVGFLVGTCSLYLLLRQAG--FTRDSGSREPGTHDKTLLEMLEEE--NKNWKKERSALFNLNHPHHTGEDGALADSLYKRVRILCWVMTGPDNLEKKARHVKATWSRHCNIVVFISSVDNPDFP-TVGLNTKEGRDQLYWKTIRAFHYVMEKHSDEADWFLKADDDTYVIVDNLRWILARHSPEDPVYFGRRFKPY----VKQGYMSGGAGYVLSKEALRRFVEGFR--TKVCTHTTS-VEDLAMGQCMEKIGVKAGDSRDTMQRETFHPFVP-ESHLT-GTFPKTFWYWNYCYYPIVQGPQCCSDLAVSFHYVDASHMYLLEYYTYHLRAFGYKYRYQPPEPNVK--APEKVETRVLEQKDKVEAQE------------EENQSPELNDKL---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08BL3-1", "uniprot_id": "C1GTA_DANRE", "id": "Q08BL3-1", "name": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A", "aln": "----------MVIMKAGSSRCAFSLGFLVGSCSLYVFLRQVW--FEESFSWQSNGRSSPSPPISHEQNSSNLTWRVEGSALINLKHPNQPGEDGHIADELFKKVRILCWVMTGPSNLQSKAQHVKNTWSRHCNVVLFMSSEEDRSFP-TVGLGTGEGRDQLYWKTIRAFHYALKNHGHEADWFLKADDDTFVVVDNLRWILSNYTPEQPIYFGKRFKPY----TKQGYMSGGAGYVLSKEALRRFVEGFS--TKVCTHTTP-VEDLAMGQCLEKMGVLAGDSRDSLHRETFHPFIP-EHHLT-GKFSKTFWYWNYCYYPIVEGPQCCSDLAVSFHYVDPVLMYTLEYYTYHLRPFGYQHRYQPPVPAVLSLLSQTVKTTTETQRSEEGAKEKPALTNSVNPRAEEVQTTETSYKITNAAQERNTTHRSAG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K237-1", "uniprot_id": "C1GLT_DROME", "id": "Q7K237-1", "name": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1", "aln": "--MTANSLLGRSILNEGRSNKRSFVSLIVGLIVGFCLA-ELFVYSTPERSEFMPYDGHRHGDVNDAHH--SHDMMEMSGPEQDVGGHEHVHENSTIAERLYSEVRVLCWIMTNPSNHQKKARHVKRTWGKRCNKLIFMSSAKDDELD-AVALPVGEGRNNLWGKTKEAYKYIYEHHINDADWFLKADDDTYTIVENMRYMLYPYSPETPVYFGCKFKPY----VKQGYMSGGAGYVLSREAVRRFVVEALPNPKLCKSDNSGAEDVEIGKCLQNVNVLAGDSRDSNGRGRFFPFVP-EHHLIPSHTDKKFWYWQYIFYKTDEGLDCCSDNAISFHYVSPNQMYVLDYLIYHLRPYGIINTPDALPN--------KLAVGELMPEIKEQATE------------------STSDGVSKRSAETKTQ-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : ..::** : * * :.:. * **.::** : *::* : .: : : : * * : : .: ***::***:*: .::*:*::: : *: .:*** .* *:*: *:: : . * : *: : * **:: * : : : * : * . * ::**** : :* *::: * : ", "identical_positions": 46, "similar_positions": 69, "identity": "10.7%" }, { "cls_id": "homologset.agr.RGD:621106", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z258-1", "uniprot_id": "KCNT1_RAT", "id": "Q9Z258-1", "name": "Potassium channel subfamily T member 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARAKLPRSPSE------------------------------GKAGPGDTPAGSAAPEEPHGLSPLLPTRG------------GGSVGSDVGQRLHVEDFSL---DSSLSQVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPDQGIGCWGCTKYNYTFNGSSSE-----------FHWAPILWVERKMALWVIQVIVATISFLETMLLIYLSYKGNIWEQIFHVSFVLEMINTLPFIITVFWPPLRNLFIPVFLNCWLAKHALENMINDFHRAILRTQSAMFNQVLILFCTLLCLVFTGTCGIQHLERAG-GNLNLLTSFYFCIVTFSTVGFGDVTPKIWPSQLLVVILICVTLVVLPLQFEELVYLWMERQKSGGNYSRHRARTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPSEMDVQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAFHAHKKYGVCLIGLKREEN-----KSILLNPGPRHILAASDTCFYINITKEENSAFIFKQEEK-------------------QKRRGLAGQALYEGPSRLPVHSIIASMGTVAMDLQN-------------------------------------------------------------TDCRPSQGGSGGGGGKLTLPTEN--------------------------------------------------------------------------------------------------GSGSRRPSIAPVLELADSSALLPCD-----------------------------------------LLSDQSED---------------------------------EVTPSDDEGLSVVEY---------------------------------------------------------------------------------------------------------------------VKGYPPNSPYIGSSPTLCHLLPVKAPFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRRELNPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSITTELTHPSNMRFMQFRAKDSYSLALSKLEKQERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKVTEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTECHVFSSEPHD----------LRAQSQISVNMEDCEDTREAKGPWGTRAASGGGSTHGRHGGSADPVEHPLLRRKSLQWARKLSRKSSKQAGKAPMTTDWITQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYEDVAN-------------------------------LTASDVMNRVN-------------------------------------------------------------LGYLQDEMNDHHQNTLSYVLINPPP----------DTRLEPNDIVYLIRSDPLAH----VTSSSQSRKSSCSNKLSSCNPETRDETQL--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZPR4-1", "uniprot_id": "KCNT1_MOUSE", "id": "Q6ZPR4-1", "name": "Potassium channel subfamily T member 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARAKLPRSPSE------------------------------GKAGPGDTPAGAAAPEEPHGLSPLLPARG------------GGSVGSDVGQR-----------------VQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPDQGIGCWGCTKYNYTFNGSSSE-----------FHWAPILWVERKMALWVIQVIVATISFLETMLIIYLSYKGNIWEQIFHVSFVLEMINTLPFIITVFWPPLRNLFIPVFLNCWLAKHALENMINDFHRAILRTQSAMFNQVLILFCTLLCLVFTGTCGIQHLERAG-GNLNLLTSFYFCIVTFSTVGFGDVTPKIWPSQLLVVILICVTLVVLPLQFEELVYLWMERQKSGGNYSRHRARTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPSEMDVQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPATSTLITLLVHTSRGQEGQESPEQWQRTYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAFHAHKKYGVCLIGLKREEN-----KSILLNPGPRHILAASDTCFYINITKEENSAFIFKQEEK-------------------QKRRGLAGQALYEGPSRLPVHSIIASMGTVAMDLQN-------------------------------------------------------------TDCRPSQGGSGGDGTKLTLPTEN--------------------------------------------------------------------------------------------------GSGSRRPSIAPVLELADSSALLPCD-----------------------------------------LLSDQSED---------------------------------EVTPSDDEGLSVVEY---------------------------------------------------------------------------------------------------------------------VKGYPPNSPYIGSSPTLCHLLPVKAPFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRRELNPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSITTELTHPSNMRFMQFRAKDSYSLALSKLEKQERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKVTEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTECHVFS-EPHD----------VRAQSQISVNMEDCEDTREAKGPWGTRAASGSGSTHGRHGGSADPVEHPLLRRKSLQWARKLSRKSTKQAGKAPVATDWITQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYEDVAN-------------------------------LTASDVMNRVN-------------------------------------------------------------LGYLQDEMNDHHQNTLSYVLINPPP----------DTRLEPNDIVYLIRSDPLAH----VASSSQSRKSSCSNKLSSCNPETRDETQL--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JUK3-1", "uniprot_id": "KCNT1_HUMAN", "id": "Q5JUK3-1", "name": "Potassium channel subfamily T member 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARAKLPRSPSE------------------------------GKAGPGGAPAGAAAPEEPHGLSPLLPARG------------GGSVGSDVGQRLPVEDFSL---DSSLSQVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDDPALGIGCWGCPKQNYSFNDSSSE-----------INWAPILWVERKMTLWAIQVIVAIISFLETMLLIYLSYKGNIWEQIFRVSFVLEMINTLPFIITIFWPPLRNLFIPVFLNCWLAKHALENMINDFHRAILRTQSAMFNQVLILFCTLLCLVFTGTCGIQHLERAG-ENLSLLTSFYFCIVTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAFHAHKKYGVCLIGLKREDN-----KSILLNPGPRHILAASDTCFYINITKEENSAFIFKQEEK-------------------RKKRAFSGQGLHEGPARLPVHSIIASMGTVAMDLQG-------------------------------------------------------------TEHRPTQSGGGGGGSKLALPTEN--------------------------------------------------------------------------------------------------GSGSRRPSIAPVLELADSSALLPCD-----------------------------------------LLSDQSED---------------------------------EVTPSDDEGLSVVEY---------------------------------------------------------------------------------------------------------------------VKGYPPNSPYIGSSPTLCHLLPVKAPFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSITTELTHPSNMRFMQFRAKDSYSLALSKLEKRERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEGDLWIRTYGRLFQKLCSSSAEIPIGIYRTESHVFS----------------TSESQISVNVEDCEDTREVKGPWGSRAGTG-GSSQGRHTGGGDPAEHPLLRRKSLQWARRLSRKAPKQAGRA-AAAEWISQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYEDVAN-------------------------------LTASDVMNRVN-------------------------------------------------------------LGYLQDEMND-HQNTLSYVLINPPP----------DTRLEPSDIVYLIRSDPLAH----VASSSQSRKSSCSHKLSSCNPETRDETQL--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IC80-1", "uniprot_id": "A0AC58IC80_DANRE", "id": "A0AC58IC80-1", "name": "", "aln": "MMTSETNCFKEDEDVLLIKYNTNTHSTKKNKAASKGKLSDMIYVVGGWSKDDPSCPVEQFCSQYNEWKFTAPMLHPRSDTGVCALDGDIYTVGGSDDVTCLSSVERYHPESNTWTVDVPSLSSPRSRVCVLEMDGCLITLGGFDGMTCINTVERYDPLKNSWSKLTPMLRNRAAASAAVLNGQIYVVGGTDGDMALDSVERFDPFEGCWSLCPTMSTPREASGCAVFLGCLYVAGGRDELGLSLSNVERYDPDNFRWSPVRAMNNKRFQVSLVVFNDFLLAIGGSDGVSDHKTMEAYDYETNSWSPRCGSRGVVLNVQDLEMTTGTSVVPSLQTYFRFRDLLLGDQTFYDDRVHVEFYVDENTFKERLKLFFIKNQRSSLRIRIFNFCLKLLTCVLYIIRVMTDNPAQ-------LRHTCVNCSSQND-----------INWELIFWVDRKVPVWAIQVIVASISFMEAMLLTYLSYKGNLWEQIFQVSFLLEMLNTVPFIITIFWPPLRNLFIPVFLNCWLAKCALESMINDLHRAIQRTHSAMFNQVLILICTLLCLVFTGTCGIQHLERAGKKSLSLFNALYFCIVTFSTVGFGDVTPQIWPSQLLVVVMICVALVVLPLQFEELIYLWMERQKSGGNYSRHRAQTERHVVLCVSTLKIDLLMDFLNEFYAHPHTQDYYVVILCPCEVDVQVRRILQIPLWSQRVIYLQGSALKNQDLLRAKMDDAEACFILSSRNEADRMAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEEFKYAMLALNCLCPATSTLITLLVHTSRGQEGQQSPEQWQRMYGRCSGNEVYHIRLGDSMFFREYNSKSFTYAAFHAHKKYGVCMIGVKREDN-----KSILLNPGPRHIMSASDTCYYINITKEENSAFIFRQEEN-------------------QGK-GRSHCDILNSPSGLPVHSIIASMGTVAMDFQN-------------------------------------------------------------TSPTESR-------LKLAPPTEN--------------------------------------------------------------------------------------------------ELGSRRPSIAPVLEIADSASLLPCD-----------------------------------------LLSDQSED---------------------------------EAGHSD-EDITATDF---------------------------------------------------------------------------------------------------------------------VKGYPPNSPYIGSSPTLCHLLPQKAPFCCLRLDQSCEHVSFEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRPRRELNPIVLLLDNLPDDHFLEAISCFPMVYYMGGTIDNLDSLLQCGVLYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSIITELTHPSNMRFMQFRAKDCYSLALSKLEKKERDKGSNLAFMFRLPFAAGRVFSISMLDTLLYQCFVKDYMIPIARLLLGLDTTPGSGYLCAMHICEADLWIRTYGRLFQKFCSSSSEIPIGIYRTESHAPP------------------ELQSSVSIDGLNDTREKG---------EESKILTRSSSSSDQSDHPLLRKKSMHWTRRLSRRSVKRSDSS----LSSIQQRLGVLRRSEREELTELVRNRMQHLGLHTGGYKDVTN-------------------------------LTASDVMNRVN-------------------------------------------------------------LGYLQDELND-QQNSISYVLINPAP----------DTLLQLNDVVFLIRPDPLAH----VPEAPPGQKRRCR--------STTDTPELN-------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DY93-1", "uniprot_id": "A8DY93_DROME", "id": "A8DY93-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQNLQVSYTALAMSDDNQTCSYSMPSVASP--------------------SLNHRLQRNVNFNEDLN----------------------------DLAGYPPQQLPTAPAVRRFSKSIFQRPRS-------------MSVWSDISRSS----------MRLDERVRVEYYVNENTFKERLQLYFIKNQRSSLRIRIADLFLKLLSCVLYIIRVILDKNPTFITCYGCEVGNKTEFIISAKLTEEEFQENPIINWDAILWVNRPTVLWVLQLLLAMVSLTQSLVLTYLGYKGNIWQQILSFHFILELVTTIPFALTIVHPPLRNLFIPIFLNCWLAKRSLENMFNDLHRAMQKSQSALSQQLTILSATLLCLVFTSVCGIQHFQRAGHRHLNLFQSTYYVVVTFSTVGYGDFVPDIWPSQLYMVIMICVALIVLPTQFEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDFYVVLLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDGDLARARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPNVPQYVQIFRPEHKLHVKFAEHVVCEDEFKYALLANNCTCPGASTLVTLLLHTSRGQEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHSHRKYGVALVGVRPAELPEFYEETILLNPGPRHIMKKDDTCYYMSITKEENSAFVVNQNQTSDPTAAAKEGSGTGGGGGASSSASHHHTAATANPTTTITTTVQATTTTISTTFTSSTLLSASTTTATINATSTAAAAPPPVPSVCVRVPHSPSYDSGGGTTGTTHLQPYPYPQSYPQPHPPMQTPDSGEFASLFVPSENPTAVIISDSRQNLKDTTVTQTAATITTTTLPPPPQTMGSPSMAGGSGGCGGGGLGLGSAHSMGTSLSITPATLTTTGNHLDVPFANNPNLLSPDVLNQRRGSRRPSILPVPDMFTSSSFSIAGNDDGEEGDESDDEIDDEMPWRSPSEKIACLGGHFPQSRTYSLIMSSSEDSYQRGCSFCSATASASAAAVAVAVAAAPAPAPAPAYPSDSAGESGTNADSAAMPSEEYLPQLRRRVMKKSYSCDSECRSVPGMGMGMAMGVGLGGGTLARLAARRRQLQRCSSCSCSTATTTTTPAVAATTAMAAGSGATAFTSSSSVETRRPVRPVWVYDYSCIVKGFPPVSPFIGVSPTLCYLLKEKKPLCCLQLAQVCEHCSYRNAKEYQWQNKTIILAADYASNGIYNFIIPLRAHFRSKTSLNPIILLLERRPDVAFLDALSYFPLVYWMLGSIDCLDDLLRAGITLAESVVVVNKELSNSAEEDSLSDCNTIVAVQNMFKFFPSIKSITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGAVFSASMLDTLLYQAFVKDYVITFVRLLLGIDQAPGSGFLTSMRITKDDMWIRTYGRLYQKLCSTTCEIPIGIYRTQDTSNADTSHVSNSPVERWGPFSAFSRHCVRLRPSYDEETGTPDSTKDSTEMLRGVTYRPPGSATGGASSFRPQPQRQRSVNCLGGCSERKGSS-YSINLADEARDNHAQQIERAEIANLVRSRMESLNLPTIDYDDVSEKRNHLSYVIINPSCDLKLEEGDLIYLVRPSPFSAQKTFERHNSRRKSNISFCSNINLGATCGPQMPQMNMNMANTAVGAGSRRGSGIAGLNPMQMQSVQTLAGYGSSSQRCSPPMQQIKSNSLSLPDSPTVVGNQRGRSNSLRIDNDILLRRSSSLRQGLPSVGVSHGRRKSSLEEIGISHFTTLMQATNHSNPIKISLNGSIGMENQISLQVTPPEEPTPMLGVPCMLGGGGGGGINPSGAGSSTGGMLGGGSSLAINTADLGPGPSTSSGASGSLQAQDSLGQQSSQVSSPQHLQGTIV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . * * . . * .*. ** ..: *:**:**:********:*:************: :: ****:*:***:**: *. . . . ::* *:**:* :*.:*:::* :*: ::::: **.****:*:**: . *:**::.*:** :*:. *********:******** :**.*:**:***: :::**: :*: ** .********..*****::*** *.*: : *: :*******:**..*.****** :*::***:*:*** ***:* : ****** **.** ***::*:***:* ::*: * :*********** **:***:*.* *:*. :* :**:*:*:*****:***.**: ** **:*::.******::** .*: ***.:****:********* * ****::**:*:*****:*****:* ***:** ** **.:***:***:*********:***:*:* **:*****:*** :*** ** **:.******:**:*:****.::*:: : ::**********: .***:*:.*********:..*::. . .*: . :: *: *:: : . : .* *:** ******* ** :: *::: .. *: ..*** . ** . : .: ***:** **:** *****:** * *:***:* : *:* *:.:** * ::** **::*: *.**:****:****::*.: .****:***:. ** **:*:. **:**:* *::* **.**:.*: *:.:***:** : ***** ::*.:*** **.**::***:. ***::.**********:* *:* ***:**:*::.**::::********* *** *********.*****:*.:.*****:* :****:* :*:: : *:********:**:**::.*********: . : .* : * . * ... .: : . : : . . :: . : : * . :: ** *:::**:.**: *.* * .*.**:: ::*...::* * * .:. . *: * * * . .. *. .: : * *...* : * : :* : .: ", "identical_positions": 563, "similar_positions": 340, "identity": "26.35%" }, { "cls_id": "homologset.agr.RGD:621107", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15631-1", "uniprot_id": "TSN_HUMAN", "id": "Q15631-1", "name": "Translin", "aln": "MSVSEIFVELQGFLAAEQDIREEIRKVVQSLEQTAREILTLLQGVHQGAGFQDIPKRCLKAREHFGTVKTHLTSLKTKFPAEQYYRFHEHWRFVLQRLVFLAAFVVYLETETLVTREAVTEILGIEPDREKGFHLDVEDYLSGVLILASELSRLSVNSVTAGDYSRPLHISTFINELDSGFRLLNLKNDSLRKRYDGLKYDVKKVEEVVYDLSIRGFNKETAAACVEK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8J8YNL9-1", "uniprot_id": "A0A8J8YNL9_RAT", "id": "A0A8J8YNL9-1", "name": "Translin", "aln": "MSVSEIFVELQGFLAAEQDIREEIRKVVQSLEQTAREILTLLQGVHQGTGFQDIPKRCLKAREHFGTVKTHLTSLKTKFPAEQYYRFHEHWRFVLQRLVFLAAFVVYLETETLVTREAVTEILGIEPDREKGFHLDVEDYLSGVLILASELSRLSVNSVTAGDYSRPLHISTFINELDSGFRLLNLKNDSLRKRYDGLKYDVKKVEEVVYDLSIRGFNKETAAACGEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62348-1", "uniprot_id": "TSN_MOUSE", "id": "Q62348-1", "name": "Translin", "aln": "MSVSEIFVELQGFLAAEQDIREEIRKVVQSLEQTAREILTLLQGVHQGTGFQDIPKRCLKAREHFSTVKTHLTSLKTKFPAEQYYRFHEHWRFVLQRLVFLAAFVVYLETETLVTREAVTEILGIEPDREKGFHLDVEDYLSGVLILASELSRLSVNSVTAGDYSRPLHISTFINELDSGFRLLNLKNDSLRKRYDGLKYDVKKVEEVVYDLSIRGFNKETAAACGEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V9N1-1", "uniprot_id": "Q4V9N1_DANRE", "id": "Q4V9N1-1", "name": "Translin", "aln": "MSVTEMFSYIQGFLSADQDIREDIRKVVQGLEQTAREILTVLQSVHQPTGFKDIPSKCLKARELFCTVRNHTGELKTKFPVEQYYRYHELWRFVLQRLAFLAAFVVYLESEALVTREEVAKILAIEVDREKGFHLDVEDYLAGVLILASELSRLAVNSVTAGDYGRPLRISNFINELDSGFRLLNLKNDPLRKRYDGLKYDVKKIEEVVYDLSIRGLAKEQEAGE-EK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*:* :****:*:*****:******.**********:**.*** :**:***.:****** * **:.* .******.*****:** ********.**********:*:***** *::**.** **************:************:*********.***:**.*****************.**************:***********: ** *. **", "identical_positions": 180, "similar_positions": 33, "identity": "78.95%" }, { "cls_id": "homologset.agr.RGD:621108", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11308-4", "uniprot_id": "ERG_HUMAN", "id": "P11308-4", "name": "Transcriptional regulator ERG", "aln": "-------------MASTIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPPNMTTNERRVIVP-ADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAPHPPALPVTSSSFFAAPNP-YWNSPTGGIYP---NTRLPTSHMPSHLGTYY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A3D6-1", "uniprot_id": "D4A3D6_RAT", "id": "D4A3D6-1", "name": "", "aln": "------MIQTVPDPEAQIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVTKGGKMVGSPDTVGMSYGSYMEEKHMPPPNMTTNERRVIVP-ADPTLWSTDHVRQWLEWAVKEYGLLDVDVLLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSTWTGHSHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSSNSNCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHTHPQKMNFVAPHPPALPVTSSSFFATPNP-YWNSPTGGIYP---NTRLPASHMPSHLGTYY---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P81270-1", "uniprot_id": "ERG_MOUSE", "id": "P81270-1", "name": "Transcriptional regulator ERG", "aln": "------MIQTVPDPAAHIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQAPARVTIKMECNPSQVNGSRNSPDECSVNKGGKMVGSPDTVGMSYGSYMEEKHVPPPNMTTNERRVIVP-ADPTLWSTDHVRQWLEWAVKEYGLLDVDVLLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSAWTGHSHLTPQSKAAQPSPSAVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSSNSNCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVSPHPPALPVTSSSFFASPNP-YWNSPTGGIYP---NTRLPASHMPSHLGTYY---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29774-1", "uniprot_id": "ETS3_DROME", "id": "P29774-1", "name": "DNA-binding protein D-ETS-3", "aln": "MYENSCSYQTALDLKRVSPPTLAQVKTEECLALGQC-SPEWTSYRFHQSTFEQLKQSVEKAKAALQ-DRSSFFGASSAFSDIYSSQRLTDSLDTLPVQSGNGGGNCLGLPHNPNVGVGVAGVLNYNAVSSSTAGVLSSSGNGVQRHRLDTLQPPSGCSPAVTQHGVITSSAGQVT--SGTLDAVSAAPALPSLTASS--SSHVEHKVRADKSTLDCATTSSHAAAPSSSSSASDHQQGRISGSKSSNTSGTGGGASASGGGGSALYSS-YKSSWGSHSSTQSQGYSSN-ALGIKHDPHSQLRQPDPYQMFGPTSSRLASSGSGQIQLWQFLLELLSDSNNASCITWEGTNGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFQGLAAATQPAASDP-TYKYQSDL-FMTPYHHSAKLSSFMSPHHGMTSSSASIFPSAASWGNWGSPATNLYQPHSMSHVTPSHVAPHLSSYPHYA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: *. ::.* :*. :. .: *: .: *: : : . * * * * ::. ...::..* :: * **: :* *.. .:. * :: . .. *:. .: .* : . . **.::*: . . .*. . : : **.* . :.* ::.* *:.. * ..*. . :: :. .*** .:. . *.. :*:* .*. .*. ::: : . ....* * ****::********..******************.*:.************:***************************************************:*:* * ** ..:. *** *** :* .** .: .*::** . ::* * ::.. *.**: .:* :::..**:..**.:* ", "identical_positions": 163, "similar_positions": 144, "identity": "32.6%" }, { "cls_id": "homologset.agr.RGD:621110", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M2X8-1", "uniprot_id": "A0ABK0M2X8_RAT", "id": "A0ABK0M2X8-1", "name": "26S proteasome non-ATPase regulatory subunit 9", "aln": "--------MSSEEVRHRAESSEARAAAVSDIQELMRRKEEIEAQIKANYDVLESQKGIGMNEPLVDCEGYPRADVDLYQVRTARHNIICLQNDHKALMKQVEEALHQLHAR--DKEKQARDMAEAREEAMNRRLA-SDSPALP--KAFARVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQ-SLQNVGSVVQHSEGKPLNVMVIRRGEKHQLRLTPTR-WAGKGLLGCNITPLQR----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR00-1", "uniprot_id": "PSMD9_MOUSE", "id": "Q9CR00-1", "name": "26S proteasome non-ATPase regulatory subunit 9", "aln": "--------MSGEDVPHRAESSEARAAAVSDIQDLMRRKEEIEAEIKANYDVLESQKGIGMNEPLVDCEGYPRADVDLYQVRTARHNIICLQNDHKALMKQVEEALHQLHAR--DKEKQARDMAEAREEAMNRRLA-SNSPVLP--QAFARVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQ-SVQNVGTVVQHSEGKPLNVTVIRRGEKHQLRLIPTR-WAGKGLLGCNIIPLQR----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00233-1", "uniprot_id": "PSMD9_HUMAN", "id": "O00233-1", "name": "26S proteasome non-ATPase regulatory subunit 9", "aln": "--------MSDEEARQSGGSSQAGVVTVSDVQELMRRKEEIEAQIKANYDVLESQKGIGMNEPLVDCEGYPRSDVDLYQVRTARHNIICLQNDHKAVMKQVEEALHQLHAR--DKEKQARDMAEAHKEAMSRKLGQSESQGPP--RAFAKVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQ-SLHNIGSVVQHSEGKPLNVTVIRRGEKHQLRLVPTR-WAGKGLLGCNIIPLQR----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFS8-1", "uniprot_id": "PSMD9_DROME", "id": "Q9VFS8-1", "name": "26S proteasome non-ATPase regulatory subunit 9", "aln": "--------------------MAAGTTTKERLERLINAKKQLEAQINRNGQILAANDNVGMSGPLVDAEGFPRNDIDVYQVRLARQTIICLQNDHKELMNQIQTLLNQYHSEIATTDPELVNRASALDLDSDRSPGGANITDLAPARAIVVVNLVSPDSPAERAGLCAGDAILRFGSINSGNFKGDLAQIGELVRNMQSQNVQLKVKRGEQQLDLILVPKT-WSGRGLLGCNIVLPPEAMDH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40555-1", "uniprot_id": "PSMD9_YEAST", "id": "P40555-1", "name": "Probable 26S proteasome regulatory subunit p27", "aln": "MEEEELSKLLANVKIDPSLTSRISQIDSFKLSELMVLKTDIETQLEAYFSVLE-QQGIGMDSALVTPDGYPRSDVDVLQVTMIRKNVNMLKNDLNHLLQRSHVLLNQHFDN--------MNVKSNQDARRN-----NDDQAIQYTIPFAFISEVVPGSPSDKADIKVDDKLISIGNVHAANHS-KLQNIQMVVMKNEDRPLPVLLLREGQILKTSLTPSRNWNGRGLLGCRIQEL------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *: * ::*:::: .:* :..:**. .** :*:** *:*: ** *:.: *:** : :::: . *:* . . : . . . : .:. :. : *.**:. *.: ..* :: :*.::: *.. .: :: :* : :.: : : : * : . * *. * *:*****.* ", "identical_positions": 40, "similar_positions": 78, "identity": "16.6%" }, { "cls_id": "homologset.agr.RGD:621111", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14AX6-1", "uniprot_id": "CDK12_MOUSE", "id": "Q14AX6-1", "name": "Cyclin-dependent kinase 12", "aln": "-------------------MPNSERHGGKKDGSGGASGTSQPSSGGGSSNSRERHRLVSKHKR-----HKSKHSKDVGLVTPEAASLGTIIKPLVEYDDISSDSDTFSDDTAFKSDRRENEERRGTDRSDRLHRHRHHQHRRSRDLLKTKQTEKEKNQEVS-KSGSMK-----------DRVSGSSKRSVEGSDDYGKAQLSKSGSKESRSSKMHKEKTRKERELKSGYKDRSKSHRKRETPKSYKTVASPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPPRSHTSSN-------------------YDSYKKSPGSTSRRQSISPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKSSPIILPKKEK------LEVKESGLESKKLPRSIKSEKSTPDTELVTVAHSNPEVKHCLDTGKVRLDENLQKHPAKDLKAQGTKDVKPVAPKEVIVTSKETETSEKETLPPLPTITSPPP-LPATTPPPQTPPLPPLPPLPAIPLQPPLPPPQPPFSQVPVSSTSILPSSPHPRTSTLSSQTNSQPPVQVSMKTQVSITAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPAKKEKEQR-------TRHLLTDLPLPPELPGGDPSPPDSPEPKAITPPQQPYK------------KRPKICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLVHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEE-SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKK--QYRRRLREEFSFIP--SAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGIVIEDPPPSKASRKETTSGTTAEPVKNNSPAPPQPAPVKAEPGPGDAVGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEASSQQQDSESIAPEESLKEVPSVPVVLPPAEQTTPEASNTPADMQNVLAVLLSQLMKTQEPAGNLEENTNDKNSGPQGPRRTPTMPQEEAAACPPHILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRSHPNRTYGNTDGPETGFSSADTDERSSGPALTESLVQTPVKNRTFSGSVSHLGESNSYQGTGSVQFPGDQDLRFTRVPLALHSVVGQPFLKSEGNSNSVVHAETKLQNYGELGPGTTGANSSGTTLQWGGPAQS--YGKPYRGAARVLPRGGRGRGVPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3MJK5-1", "uniprot_id": "CDK12_RAT", "id": "Q3MJK5-1", "name": "Cyclin-dependent kinase 12", "aln": "-------------------MPNSERHGGKKDGSGGASGTSQPSSGGGSSNSRERHRLVSKHKR-----HKSKHSKDMGLVTPEAASLGTIIKPLVEYDDISSDSDTFSDDMAFKSDRRENDERRGTDRSDRLHRHRHHQHRRSRDLLKTKQTEKEKNQEVS-KSGSMK-----------DRLSGSSKRSVEGNDDYGKAQLSKSSSKESRSSKMHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPPRSHTSSN-------------------YDSYKKSPGSTSRRQSISPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPISSRKSMKSRSRSPAYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKLDGKESKGSPIILPKKEK------FEVKESGLESKKLPRGIKSEKSTPDTELVNVAHSNTEVKNCLDTGKVKLDENLQKHPVKDLKAQGTKDTKPVALKEVIVTSKETETSEKEALPPLPTITSPPP-LPSTTPPPQTPPLPPLPPLPAVPLQPPLPPPQPPFSQVPVSNTSTLPSSPHPRTSTLSSQTNSQPLVQVSMKTQLSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKEMLPSKPAKKEKEQR-------TRHLLTDLPLPPELPGGDPSPPDSPEPKAITPPQQPYK------------KRPKICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLVHQSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEE-SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKK--QYRRRLREEFSFIP--SAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGIVIEEQPPSKASRKETTSGTAAEPVKNSSPAPPQPAPVKAEPGPGDAVGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEASSQQQDSESIAPEESLKEVPSVSVVLPPAEQTTPEASNTPADMQNMLAVLLSQLMKTQEPAGNLEENTSDKNSGPQGPRRTPTMPQEEAAACPPHILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRSHPNRTYGNTDGPETGFSATDTDERSSGPALTESLVQTLVKNRTFSGSVSHLGESNSYQGTGSVQFPGDQDLRFTRVPLALHSVVGQPFLKSEGNSNSVVHAETKLQNYGELGPGTTGANSSGTTLQWGGPAQS--FGKPYRGAARVPPRGGRGRGVPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NYV4-1", "uniprot_id": "CDK12_HUMAN", "id": "Q9NYV4-1", "name": "Cyclin-dependent kinase 12", "aln": "-------------------MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKR-----HKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMK-----------DRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSN-------------------YDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENS----SVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQANSQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQR-------TRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYK------------KRPKICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEE-SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKK--QYRRRLREEFSFIP--SAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVKNSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSLSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q03957-1", "uniprot_id": "CTK1_YEAST", "id": "Q03957-1", "name": "CTD kinase subunit alpha", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYNNGNTYSKSYSRNNKRPLFGKRSPNPQSLARPPP-------------------------PKRIRTDSG-------------------YQSNMDNISSHRVNSNDQPGHTKSRGNNNLSRYN------DTSFQTSSRYQGSRYNNNNTSYENRPKSIKRDETKAEFLS--HLPKGPKSVEKSRYNNSSNTSNDIKNGYHASKYYN---------------------------------------HKGQEGRS-----------------------VIAKKVPVSVLTQQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQ---------KTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSR---ADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYFK--EEPKPEPLVLDGLVSCHEYEVKLARKQKRPNILS-------TNTNNKGNGNSNNNNNNNNDDDDK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VP22-1", "uniprot_id": "CDK12_DROME", "id": "Q9VP22-1", "name": "Cyclin-dependent kinase 12", "aln": "MHASSAAATALVEYSDVSSEDFSDQEAGDLDADAGKGAGNIKKPKPAPDNQFSKGRLDAKPDKEGYDNYRSRRAEDSSDPVAAGSRQTSSSEATNPREEPSQASNTSKDELWGREIYMSSDSIDTDELEAEMKRQKRKKQKKEKHKHKSKKKSKKRKKKRAKSYSSIDSMSDNDINALLDRRYTPPTAPSKSNERTVSAAPSSFTPHNLKESSSPATPPPVRRPNTNSNYYGESSLETANSALGSNLQVTVTNKQSISNRLRSPPPSSRSSGNGPRFGNSPRTPPPSHYSSSGGGGVGSGSVVRDSRSSRYVNSPHKEDVSAHHRSSHDHGYQGRYSGAGSSSHDTRKVKRLSPELDRYNHQPSTPPHKRRKFSDGREVGLGNFEHSRHHSGKYERYSRDRYSRRSSRSPSVQHSRSRQSPSGGLSSGSNAFRHGGSHKHKYGTTVSSTPSHTTRTSKRASGTGTSGDRYSRSPRTSSRYMESSPPSPVGASGSHHYHHRRSPRMRQRTRGDSRRRSPSSASSESSASRSRSPTSRDLKHKREEYIKKISETSLFAELVKDRHKRQKALKEIIERQEENSNSNSNGALTINDNSSSVDGNTPNAADGRSAPGSGTPAAASTTSNGLQALGSKPDLDLNNIPMPNKQNDSVVSNPASNADVPDSVAQLKQPLLVPPFSASKNNIKPKSLTSLPLPPGMNVLDLAGARSPSPGQKKESDEKNVTSSGSANKSVLNLPMPPVIPGSEELSGDDDVIDSPEDFDAPAVGTVHGHGGGPGTTRQRPVILNRRDSRNNVRDWGERCVDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKK--THRRRLREDFEFMP--APALDLLDKMLDLDPDKRITAEDALRSPWLRKINPDEMPTPQLPTWQDCHELWSKKRRRQMREQQESLPPTVIASTKYQQHGATMVGDA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... .. .. : . : . . * :.*. .. .. .: . . . . :: . ... .: .: .. . . . . . . .:* . * . : . :. . . . .:. : : :: :. *... : * :******:****:: .* .:*****:**: *:******::****:*:.: * .: .::**:.:.* :.*::*** *:** *** . *.:...: ::***: *::* *.:::****:* ****::* *::*::****** *: ***:************** .* . :*:*.***:* *** * .:**.. *: *:* * :: *:* ** : .:* * : :: : ..: *.*. : : .*:* ::* * ** :* ::*:* ::: : : . * .*** * *:* : :. : ... ", "identical_positions": 134, "similar_positions": 174, "identity": "8.52%" }, { "cls_id": "homologset.agr.RGD:621112", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54852-1", "uniprot_id": "KCNH7_RAT", "id": "O54852-1", "name": "Voltage-gated inwardly rectifying potassium channel KCNH7", "aln": "-MPVRRGHVAPQNTFLGTIIR----------------------------KFE-----------------------GQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDEDNAASPERVNPILPVKSVNRK--LFGFKFPG-LRVLTYRKQSLPQEDPDVVVIDSS----KHSDDS------VAMKHFKSPTKESCSPSEADDTKALIQPSQCSPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLTHSRSRESLCSIRRASSVHDIEGFNVHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSDVKTEKKNTSPPSSDKTIIAPKVKERTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAVHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGTQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAK-----SQSINDSEGDTCKLRRRRLSFESEGDKDFSKENSANDADDSTDTIRRYQSSKKHFEEKKSRSSSFISSIDDEQKPLFLGTVDSTPRMVKASR-HHGEEAAPPSGRIHTDKRSHSCKD--ITDTHSWEREHARAQPEECSPSGLQRAAWGISETESDLTYGEVEQRLDLLQEQLNRLESQMTTDIQAILQLLQKQTTVVPPAYSMVTAGAEYQRPILRLLRTSHPRASIKTDRSFSPSSQCPEFLDLEKSKLKSKESLSSGKRLNTASEDNLTSLLKQDSDASSELDPRQRKSYLHPIRHPSLPDSSLSTVGILGLHRHVSDPGLPGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER47-1", "uniprot_id": "KCNH7_MOUSE", "id": "Q9ER47-1", "name": "Voltage-gated inwardly rectifying potassium channel KCNH7", "aln": "-MPVRRGHVAPQNTFLGTIIR----------------------------KFE-----------------------GQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDEENAATPERVNPILPVKTVNRK--LFGFKFPG-LRVLTYRKQSLPQEDPDVVVIDSS----KHSDDS------VAMKHFKSPTKESCSPSEADDTKALIQPSQCSPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLTHSRSRESLCSIRRASSVHDIEGFSVHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSDVKTEKKNTSPPSSDKTIIAPKVKERTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGTQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAK-----SQSVNDSEGDTGKLRRRRLSFESEGEKDFSKENSANDADDSTDTIRRYQSSKKHFEERKSRSSSFISSIDDEQKPLFLGTVDSTPRMVKATR-LHGEETMPHSGRIHTEKRSHSCRD--ITDTHSWEREPARAQPEECSPSGLQRAAWGVSETESDLTYGEVEQRLDLLQEQLNRLESQMTTDIQAILQLLQKQTTVVPPAYSMVTAGAEYQRPILRLLRTSHPRASIKTDRSFSPSSQCPEFLDLEKSKLQSKESLSSGRRLNTASEDNLTSLLKQDSDASSELDPRQRKTYLHPIRHPSLPDSSLSTVGILGLHRHVSDPGLPGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS40-1", "uniprot_id": "KCNH7_HUMAN", "id": "Q9NS40-1", "name": "Voltage-gated inwardly rectifying potassium channel KCNH7", "aln": "-MPVRRGHVAPQNTFLGTIIR----------------------------KFE-----------------------GQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDNENAATPERVNPILPIKTVNRK--FFGFKFPG-LRVLTYRKQSLPQEDPDVVVIDSS----KHSDDS------VAMKHFKSPTKESCSPSEADDTKALIQPSKCSPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGFGVHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSSPPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAKADLLRSQSMNDSEGDNCKLRRRKLSFESEGEK----ENSTNDPEDSADTIRHYQSSKRHFEEKKSRSSSFISSIDDEQKPLFSGIVDSSPGIGKASG-LDFEETVPTSGRMHIDKRSHSCKD--ITDMRSWERENAHPQPEDSSPSALQRAAWGISETESDLTYGEVEQRLDLLQEQLNRLESQMTTDIQTILQLLQKQTTVVPPAYSMVTAGSEYQRPIIQLMRTSQPEASIKTDRSFSPSSQCPEFLDLEKSKLKSKESLSSGVHLNTASEDNLTSLLKQDSDLSLELHLRQRKTYVHPIRHPSLPDSSLSTVGIVGLHRHVSDPGLPGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JTJ6-1", "uniprot_id": "A0AC58JTJ6_DANRE", "id": "A0AC58JTJ6-1", "name": "", "aln": "MIRSRAQQLLTDTVGLKTVFKSSSYVFHYGTNINHVLKDILDTVCRLMIAFQSMVELEVHIRLNEVPKQNIFNQVNIYKRFVIANARVQNCAIIYCNDAFCEMTGFSRPDVMQKPCTCDFLHGQLTKRHAIAQVAQALMGSEERKVEITYHRKDGSDFLCATHIIPVKNQEGVVMMFILSFDYVLKEGSMDSLDRLNHTSPARQEQKKGRFFRFRLPAPLSMLGVSKQSLPQEDPDEVTIHSADQNEKHSSCSSSLSLSLSPRELHPPTGESCSPSYGNDTRALIGQSYLGSCSPISGPQDHSSPRGPWERVDP--QESLATASRRASRASMCTFRRASSTQDLEGLSTHTQRTYRDRHASE-------GPFNQIKSSLLGSTSDSNLTKYSTINKIPLITLNFSETNHDKRPSSPHSSEKTIIAPKVKDRTHNVTDKVTQVLSLGADVLPEYKLQTPRINKLTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDPEEEKRRECGYSCSPLNVVDLIVDIMFIVDILINFRTTYINANEEVVSHPAKIAVHYFKGWFFIDMVAAIPFDLLIFEGGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERLYLDHTIGWLDNLGISIGKQYNISDDASGPSIRDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHLQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNKTLLQSCKAFRGATKGCLRALAMRFKTTHAPPGDTLVHGGDVLTALYFLARGSIEILRDDIVVAILGKNDIFGEMIHLYAKPGKANADVRALSYCDLHTINREDLLEVLDMYPEFSDYFLSNLELTFNLRDENSK--------------DTTAPQRTLYTAVS-----------DSDTED-PDVRKRRRSTDSPIRPSRSDR----ERVRDRELHTLPGKEEEEEDEEETSRPLGLGQSLPVNLNTMPDPHTKDCVENNLFQKDVCVEEWPCGNADDSAKS---QDREGGDDCESDITFGEMEQRLDLLQENLNRLEAQMTSDIQAVLQLLQRQSALGPPAYSTVAVSPEYQKPIQPVTAIQTQSPDLENAKDSRP-----------AVPIETTSDVTAATPLVTDTQWEAELGLKPAENEASAS--QQPRALQMSIRQASLPDSAPAAGHTPALHRPSSDPGLPGQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :: .:.. * *::: *: . *:*:****************.************************ **** ***:****:********:**::*:** *:* ************.****:.*:** .: . : :*:* * : ::* :* *::*. * :* ********** *.*.*: ***. * :: :.::.** ****** .:**:*** * .. **** *****: *:*: * :* : :: ** *:*::*****.:*:**:..*.:. :******* ****:**************.********* :*****:.: :*: :** **:*********:******:*************************:************************************* **:************************:**********:* ******.*****:*******:************** .**************************************************************** ** ..*****.** .***:** **.:*****:******************************************************************:**********************************************************:****.*******:*********:************** **********:*******:*****************:********:*******:*****.*:****************:**:*********.*.:* *. :* : * .*.:* .*. :: :*:. :. :* . : *.: : * :. ::: :: * . . : :::.* : : : .* . :.::.: * : * .: ***:*:**:*********:*****:***:***::*****:*::: ***** *:...***:** : . ..::. :. * :::...:::. * * :: : ** .: : :* :: .**:.*****: :: .*** *******:", "identical_positions": 755, "similar_positions": 223, "identity": "59.54%" }, { "cls_id": "homologset.agr.RGD:621113", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38585-1", "uniprot_id": "TTL_MOUSE", "id": "P38585-1", "name": "Tubulin--tyrosine ligase", "aln": "-----------------------------------------------------------------------------------------------------MYTFVVRDENSSVYAEVSRLLLATG----------------------------------------------YWKRLRRDNPRFNLMLGER------------------------------------------------------------------------------------------------------------------NRLPFGRLGHEPGLAQLVN----------------------YYRGADKLCRKASLVKLVKTSPELSES--------------------------CSWFPESYVIYPTNLKTPVAPAQNG--------------------IQLPVSNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFID---------------------------------SQGQVHVIQKYLERPLLLEPG-HRKFDIRSWVLVDHQYNIYLYREGVLRTASEP--------YHVDNFQDKTCHLTNHCIQKEYSKNYGKYEEGNEMFFEEFNQYLTSALNITLESSILLQIKHIIRSCLMSVEPAISTKHLPY-QSFQLLGFDFMVDEELKVWLIEVNGAPACAQK------LYAELCQGIVDIAISSVFPPPDTEQVPQQPAAFVKL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QXJ0-1", "uniprot_id": "TTL_RAT", "id": "Q9QXJ0-1", "name": "Tubulin--tyrosine ligase", "aln": "-----------------------------------------------------------------------------------------------------MYTFVVRQENSSVYAEVSRLLLATG----------------------------------------------YWKRLRRDNPRFNLMLGGR------------------------------------------------------------------------------------------------------------------NRLPFGRLGHEPGLAQLVN----------------------YYRGADKLCRKASLVKLVKTSPELSES--------------------------CSWFPESYVIHPTNLKTPVAPAQNG--------------------IQLPVSNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFID---------------------------------NQGQVHVIQKYLEHPLLLEPG-HRKFDIRSWVLVDHQYNIYLYREGVLRTASEP--------YHVDNFQDKTCHLTNHCIQKEYSKNYGKYEEGNEMFFEEFNQYLTSALNITLENSILLQIKHIIRSCLMSVEPAISTKHLPY-QSFQLLGFDFMVDEELKVWLIEVNGAPACAQK------LYAELCQGIVDIAISSVFPPPDTEQVPQQPAAFMKL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NG68-1", "uniprot_id": "TTL_HUMAN", "id": "Q8NG68-1", "name": "Tubulin--tyrosine ligase", "aln": "-----------------------------------------------------------------------------------------------------MYTFVVRDENSSVYAEVSRLLLATG----------------------------------------------HWKRLRRDNPRFNLMLGER------------------------------------------------------------------------------------------------------------------NRLPFGRLGHEPGLVQLVN----------------------YYRGADKLCRKASLVKLIKTSPELAES--------------------------CTWFPESYVIYPTNLKTPVAPAQNG--------------------IQPPISNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFID---------------------------------NQGQVHVIQKYLEHPLLLEPG-HRKFDIRSWVLVDHQYNIYLYREGVLRTASEP--------YHVDNFQDKTCHLTNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEPAISTKHLPY-QSFQLFGFDFMVDEELKVWLIEVNGAPACAQK------LYAELCQGIVDIAISSVFPPPDVEQPQTQPAAFIKL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38254-1", "uniprot_id": "TTL_YEAST", "id": "P38254-1", "name": "Probable tubulin--tyrosine ligase PBY1", "aln": "MRVLITNDDGPLSDQFSPYIRPFIQHIKRNYPEWKITVCVPHVQKSWVGKAHLAGKNLTAQFIYSKVDAEDNTFWGPFIQPQIRSENSKLPYVLNAEIPKDTIEWILIDGTPASCANIGLHLLSNEPFDLVLSGPNVGRNTSAAYITSSGTVGGAMESVITGNTKAIAISWAYFNGLKNVSPLLMEKASKRSLDVIKHLVKNWDPKTDLYSINIPLVESLSDDTKVYYAPIWENRWIPIFNGPHINLENSFAEIEDGNESSSISFNWAPKFGAHKDSIHYMDEYKDRTVLTDAEVIESEMISVTPMKATFKGVNHLLGELKLTEEENNLSKTNNLIVVSIDPMEYIYKPLTHALKKYLPQVEIVSNLPEFDNGGCEKEMKVFHYGDYEQLDMDKLMELPNNYFTNSYIYRKALIRKHFLSHTIQTYTAKNPESILKKAYLESFTIDLDYAEFLDDALDENWELRQELENESQDKWWIVKPSMSDKGQGIRVFKTIEDLQAIFDSFDDEDSEAEESGNDDDADDVNGEFMDNNKVNISQLRHFIIQEYLTNPLLLASMDNRKFHIRCYVVCRGDLQVFVYDRMLALFAAKPFVPLDPYAYSVTDLKDLECHLTNTCLQSKKKD-----KDSSVLEFDSIEEIPN-----ERKSNIKEQIHSITNDVFLAAVNVNRLNFQPLPNAFETYGVDFLIDSNYEVKLLEINAFPDFKQTGKDLKNLIDELFDDTVKYCVTPIFNENRNKTDDETDPNFVKVIDYTSNGW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : ..: *::. **:. ::: *:. .* : . * : .* :.* * :*.: * :. * : . *:::.. **: :. .:*.:**: : ::. . . *: :: * : :. :::.:.: **.*.* . **:** : . .:* ::* .* : .:**:** .**** . :***.**.:*: : ::::* . : *::* * * :::* ***** *:*.: .. ::.. : *..::: . :..* **: * .. :::. . :. * ::*: *.**::*.: :* *:*:*. * *. * ** :. *. .::.:* : . *:*: ", "identical_positions": 82, "similar_positions": 151, "identity": "10.75%" }, { "cls_id": "homologset.agr.RGD:621114", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUN3-1", "uniprot_id": "A0A8I5ZUN3_RAT", "id": "A0A8I5ZUN3-1", "name": "Titin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRETTMTSSTQIRREERWEGRYGVQEQVTISGAAGTAASVSARSSFTAEAVTTGAKEVKQETDKSAAVATVVAAVDMARVREPVISAVEQTAQRTTTTAVHVQPAQKQMRKEAEKTAVTKVVVAADKAKEQELRLRTREEIITKQEQTHIAHEQIRKETEKAFVPKVVISATKAKEQETRITGEITTKQEQKRITQETV------------------------------------------------------------------------------------------------------------------------------------------GVGKKAEAVATVVAAVDQARVREPREPRHVEESYSQQTTLEYGYKEHISATKVPEQPQRPASEPHVVPKAVKPVVIQAPSETHIKATDQVGMHISSQVKKTTDISTERLVHVDKRPRTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSTTSSTQKITKSVKAPTVKPGETRVRAEPTPSPKFPFADVPAPDTYKSQAGIEVKKEVGVSISGSTVREEQFELLRGREAKVTETARVPAPAEVPVTPPTLVSGLKNVTVVEGESVTLECHISGYPSPKVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFDKETT-LTEKFTTEEKRFVESRDVVMTDTSITEEQAGPGEPAAPFFISKPVVQKLVEGGSVVFECQIGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECRLVISMTFADDAGEYTIVIRNKHGETSASASLLEEADYEALIKSQQETLYQTQMSTFIQEPKVGEIAPGFAYSEYEKEYEKEQALIRKKMAKDTVMVRTFVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEERMAVDISESEAVESGFDIRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIRRGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPFSAPTYMPTPEAVSRIRSVSPRSVSRSPIRISPAMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPASFKCLEGQTARFDLKVVGRPMPETFWFHNGQQIVNDYTHKVVIKEDGTQSLIIVPALPSDSGEWTVVAQNRAGKSTISVTLTVEAVEHQIKPAFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPRIRIEGTKGEAALKIDSTISQDSAWYTATAINKAGRDTTRCKVNIEVEFAEPEPERRLIIPRGTYRAKEISAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRLINEFGYCSLDYEAAYSRDSGVITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGKKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLFPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVTEHKVKLEIQQREDFRSVLRRAPEPKPEFHVHEPGKLQFEVQKVDRPVDTGETKEVVKLKRAERITHEKVSEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLKKTKDELLHWTKELTEEEKKALAEEGKVTIPTFKPERIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGIEVHAGDKYRMHSDRKVHFLSVLTIDTSDAEDYSCVLVEDENIKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIISPENIEGKWYHNDVELKSNGKYSITSRRGRQNLTVKDVTKEDQGEYCFVVDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLENVEGVWMKDGQEVQHSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGNVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQSIVKGTKQRLVINRTHASDEGPYKLMVGRVETSCNLSVEKIKIIRGLRDLTCTETQNVVFEVELSHSGIDVVWNFKGQEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGEYAFYAGENTTSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANPESEGEWLKDGKHLTLSNNFRSESDGHKRRLVIAAAKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLRNLTVTETQDAIFSVELTHPDVKGVQWIKNGVVLDSNDKYEISVKGTLYSLKIKNCAMADESVYGFKLGRLGASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMRNIEVPETKAASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDRCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDGQELQIVDRIKIQKEKYVHRLLIPSARMSDAGKYTVVAGGNMSTANLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVEERHQYVVERRIHRMFISEARHSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVIAGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIVTPLQDAVTSEGRPARFQCQVSGTDLKVSWYCRDKKIKPSRFFRMTQFEDTYQLEIAEAFPEDEGTYAFVANNAVGQVSSTATLRLEAPESILHEQIGQQIEMEMK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAPVIKRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSNYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFLCTVSGTPVIETIWQKDGTALSPSPDCRITDADNKHSLELSNLTVQDRGVYSCKASNKFGADICQAELTIIDKPHFIKELEPVQSAINKKIHLECQVDEDRKVSITWSKDGQKLPAGKDYKIYFEDKIASLEIPLAKLKDSGTYSCTASNEAGSSSSSATVAVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMSFANSEAILDITDVKVDDSGTYSCEATNDAGSDSCSTEVVIKEPPSFIKTLEPAHIVRGANALLQCEVAGTGPFEVSWFKDKKQIRSSKKYRLFTQKTFVFLEITSFNSADIGDYECVVANEVGKCGCVATHLLKEPPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSSGVAVLTISDVQIGLGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVSGTPELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKEIAASDRYQIAFVEGTASLEISRVDMNDAGNFTCRATNSVGSKDSRGALIVQEPPSFVTKPESRDVLPGSAVCLKSAFQGSTPLTIRWFKGDKELVSGGSCYITKEASESSLELYAVKTTDSGTYTCKVSNVAGSVECSANLFVKEPATFTEKLEPSQLLKKGDATQLVCKVTGTPPIKITWFANDRELRESSKHKMSFVESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHCTSIVIVKESPYFTKEFKSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFIQDQLVSLQILKFVASDAGEYQCRVTNEVGSSTCSARVTLREPPSFIKKIETTSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEISAKWFKDGQELTLGPKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKLRKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASDKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHSQCSGHLTVKEPPYFVEKPQSQDVNPSTRVQLKALVGGTAPMTIKWFKDNKELHPGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTTSSKATIFVKEPPQFIKKPSPVLVLRNGQSTTFECQVTGTPEIRVSWYLDGNEITDLRRYGISFVDGLATFQISNARVENSGTYVCEARNDAGTASCSIELKVKEPPIFIRELEPVEVVKDSDVELECEVMGTTPFEVTWLKNNKEIRSGKKYTMSEKMSVFYLHITKCAPSDVGEYQCIIANEGGSCACTARVALKEPPSFIKKIENVTTVLKSSATFQSTVAGSPPISITWLKDDQILEENDNVHISFEDSVATLQVRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIIEKAKSVDVTEKDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPINAQWFKDGKEISTSAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVKEPPSFLVKPERQQAIPDSTVEFKAVLKGTPPFKIKWLKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCQVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSARLECKITGSPEIRVVWYRNEHELTASDKYQMTFIDSVAVMQMNSLGTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPVVETLKNTEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHASIHILNVDSTDIGEYHCKAQNEVGSDTCICAIKLKEPPKFISKLNSLTVVAGEPAELQASIEGAPPISVHWLKEKEEVVRESENVRISFVNNVATLQFAKAEPANAGKYICQVKNDGGVRENMASLTVLEPAVIVEKAGSMTVTVGETCSLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLKDIGGVLGTSCVLECKVAGSSPISIAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAGSDECRALLTVQEPPSFVKEPEPLEILPGKNITFTSVIRGTPPFKVGWFRGARELVKGDRCNIYFEDTVAELELFNIDVSQSGEYTCVVSNNAGQASCTTRLFVKEPATFVKKLSDHSVEPGKSIILEGTYTGTLPISVTWKKDGVVITPSERCNIVTTEKTCILEILTSTKGDAGHYSCEIENEAGRDSCDALVSTLEPPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWFKGDTKLRSTPEYRTYFTNNVATLVFNKVGINDSGEYTCVAENSIGTAASKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIHVCWYRDGVLLRDDENLQMSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFIKKLDTSKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESWKYNMSFVNSVALLTINEASVEDTGDYICEAHNGVGHASCSTALKVKAPPVFTQKPPPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKVTSKNFDTSLHIFNLEAPDIGEYHCKATNEVGSDTCACTVKFKEPPRFVKKLSDVSTLIGDPVELQAVVEGFQPISVVWLKDKGEVIRESENVRISFVDNIATLQLGSPEASHSGKYVCQIKNDAGMRECSALLTVLEPARIVEKPEPMTVTTGNPFTLECVVAGTPELSAKWLKDGRELSSGSRHHITFVRNLASLKIPSAEMNDKGLYSFEVENSVGKSSCTVSVHVSDRVVPPSFIRKLKDTTATLGASVVLECRVSGSAPISVGWFLDGNEIISSPKCQPSFADNVCTLTLSSLEPSDTGAYTCVAANVAGQDESSALLTVQEPPSFEQTPDSVEVLPGMSLTFTSVFRGTPPFKVKWFKGSRELESGEACTISLEDFVTELELLEVEPLQSGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADTSVETGSPIVLEATYSGTPPIAVSWLKNEYPLSQSPNCGITTTERSSILEILESTIEDYAQYACLIENEAGQDICEALVSVLEPPYFIEPLEHVEAAIGEPTTLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGQLLKDDSNLQMSFVHHVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGSFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVAKGDAGQYTCYASNVAGKDSCSAQLGVQEPPRFIKKLDQSRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMS-----FEDSVAILEMHNLSVEDSGDYTCEARNAAGSASSSTSLKVK-------EPPVFRKKPFPVETLKGADVHLECELQGTPPFQVSWYKDKRELRSGKKYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGSDTCVGSVTLKAPPQFVKKLSDVSTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWISHSENVATLHFSRAEPANAGKYTCQIKNDAGVQECYATLSVLEPATIVEKPESIKVTTGDTCTLECMVSGTPELSTKWFKDGKELTGDSKYKISFFNKVSGLKIISVAPGDSGVYSFEVQNPVGKDSCTVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVFGSPPISVLWLHDGNAISSGRKYQTTLTDNTCALTVNMLEDADAGDYTCIATNVAGSDECSAPLTVREPPSFVQKPDPMDVLTGSNVTFTSIVKGTPPFTVSWFKGSSELVPGARCNVSLQDSVAELELFDVDTSQSGDYTCIVSNEAGRASCTTQLFVKAPAIFVKRLNDYSIEKGKPLILEGTFSGTPPISVTWKKNGVNVTASQRCNITTTEKSAILEILSSTVEDSGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPLKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTCKMHFKNNVATLVFTQVDSNDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNVQTSFLDNIATLNIFKTDRSLAGQYSCTVTNPIGSASSSAKLILTEGKNPPFFDIPLAPVDAVVGESADLECHVTGTQPIKVTWAKDNREIRSGGNYQISYLENSAHLTIVKVDKGDSGQYTCYAINEVGKDSCTAQLNIKERLTPPSFTKKLSETIEETEGNSFKLEGRVAGSQPITIAWYKNNVEIHPTSNCEITFKNNALLLQVKKASMADAGLYTCKATNDAGSALCTSSIVIREPKKPPVFDQHLTPVTASEGDFLQLSCHVQGSEPIRIQWLRAGREIKPSDRCSFSFASGTAVLELKDTAKADSGDYVCKASNVAGSDTSKCKVTIKEKPAAAPAAKKAAVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRILIHQKGDESKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPALKKGSGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEELEKSERDEKEFEELVSFIQQRLTQTEPVTLIKDIENQTVLKDNDAIFEIDIKINYPEIKLSWYKGTEKLEPSNKYEITINGDRHTLRVRNCQLKDQGNYRLVCGPHIASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRVLKPQGRVKTEVEHKVHKLTIADVRAEDQGRYTCKHEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLEMKPPDIPDSRVPIPTMPIRAVPPEEIPPAVAPSIPLLLPLPEEKKPPAKRIEVTKKGVKKDTKKVVAKPKEEAPPPPPVPEVAKKPPPPTPMIPAKPSEIIDVSSKAEEVKITTITRKKEIHKEKEAVYERKEAVY-EKKVLIEPWEEPYEELETEPYTEPYEEPYYEEPDEDYEEIKVEAKKEVHEEWEEDYEEGQEYYEREEGYDEGEEEWEEIYHEREIIQVQKEVHEDLHEKKIPAKVPEKKVPPP-KVVKKPVVEKIEKTTRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEIIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPE---------------------------PPKKPVPEEVVPVPIPKKVEPPAVKVPEAPKKPVPEEKKPVPIPKK-EPAAPPKVPEAPKKPAPEEKTAVPVAKKKEAPPPKVTEVQKKVVTEEKITIIPQREESPPPAVPEIPKKKVPEEKRPVPRKEE--VPPP--KAPPKKPVPEEVVPVPIP---KKAPPRAEVSKKTVVEEKKFAAEERLSMAVPQRVELMRHEE---EEWTYSEEEEQVSVSVYREEERDEEE-AEITEYEVLEEPEEYVVEEKLHVISKRVEVEPAKVPEKHEKKIIPRPKVPAKIEEPPPTKVPEPPKKMVPEKKVPAPPPKK--VPPAKAPEEPKKPVPERRVPAEVVEIEEPPPTKVTEKHMKITQEEKVLVAVTKKEEPPRARVPEEPKKVVPEEKFPKLKPRREEEPPAKVTEVRKRAVKEEKVSIEVPKREPRPTKEVTVTEEKKWSYTREEETVLEHREEEYEDYEDYEEYKEYEEYEPTEEYDQYDEYAERELEHYEEAKEQEEYVVPEPKKPITRKPA-QEPVPAKPKAPPPKVPKKAIPEEKAPLLIQKKLKPLPPKAPEEPKKVVEEKIQISITKREKQQVTEPVAKVPG--------------------------VPKKREPEEVVIFKEEVEAHEEEYIVEEEEEYVHEEEYVHEEEYIHEEEYVHEEEYIHEEEEYLH-EEEVIAEEEVLPVAPVKVPVVPKKPVPEEKKPVPVPKKKEAPPAKVPEIPKKPEEKVSVPVPKKEKAPPAKVPEVPKKPVPEEKAPVPVPKKVEPPPAKVPEVPKKPVPEKKVPAPTPKKVEAPPAKVPEVPKKPIPEEKKPTPLLKKMEAPPPKVPKKREVVPVPVALPREEEEEEAPFEEVT---------VPEEEILPEEEVPPEEEEVLPEEEEVLPEEEEVPPE------EEEALPEIKPKVPKPAPVPKKTVPEKKVPVPVAKKVEPPPPPKVPEIKKKVPEKKVVVPKKEEAPPTKVPVVPKKPEPEKKVPAPALKKAVVPPAKVPEVPKRVEEKRIVPPKEEEVPPAKVYEEAEEP--TPEETPEEPPSIEEEEIVEEEEEEE-VPPPRAPEVVKKAVPAAPAPVPKKAEAPPTKVPKKIPEEKVPVPVQKKEAPPARVPEVPAKVPEK-KKIPEKKVPVPKKEAVPPAKGKAVFEEKISVAYQQEERVQERIELELVEAQVEEAFEEEQFHEVQEYFEEEEFHEVEEFIRVEERRFQEEHKVEEVHRVIEFLEAEEVEVHEKPKIPPKKGPEVSEKVIPPKKPPTKVLPRKEPPAKAPEVTKKMVVEEKVRVPEEPKVPAPKAPEVPKKITPEEKVHEAVPKKPEAPPPKVPEVPKKIIQEEKLPVVLPEDTEIYIYEASEETVIEEEHVIHPQKARLKVAKAPAPPQTVVTEEKTYVTIRKTRETLAHTESETTREAFPELKSYEAVPEIPEPPSPEDLEVIEDVLTEKQPPPTKRRKPLLPAAPEAMREMTPEMNTFEDNSAEPETPPVQEPEGPPEVDDAMRAPSKPRRAPSVTVRDTYQEATVEKKTLRISRKKPELPPDE-VPEAPREVVAKKKVPPPQVPEVVPVKAPGTPKEVVSERKLLEEPSKKPAVLPVPVPEEPKEVIPEKKVSLVPAKKPAAPPTTVPEAHEEDFPEEEVPLVLPQEPEAPPAKVPEPPKEVVPEKKVSMVPPKRPEAPPAKVPEAPKEVVPEKKVSVAPKKKPEAPAVKVPEAPKKVVPEKKVPVAAPKKPEAPAAEVPEVPKAAVPQKKIPEAVPPKPESPPPEAPEVPPKEVTPEKKVPVVPPKKPEAPPPKVPETPQEAVSEEKTPKALPKKAEAAPVPVPEVQETVPEKTRPAAPPKKPEATPMPVPKVQEIVPEKTRLMAPSKKPEATTVPVPEVQEIVPEKTRPVAPPKKPEATTVPVPEDQETVPEKTRPVAPPKKPEVTPVPVPKVQEIVPEKTRPAASPKKPEATPVPVPEIQGTVPEKTRTVGPPKKPEAIPVSVPEVQEPIPEKTRPAAPPKKPEVTTVP--------------------------------------------------VPEEPKEVIPEKKVSLVPAKKPAAPPTTVPEAHEEDFPEEEVPLVPPQEPEAPPAKVPEPPKEVVPEKKVSMVPPKRPEAPPAKVPEASKEVVPEKKVSVAPKKKPEAPAVKVPEAPKKVVPEKKVPVAAPKKPEAPAAEVPEVPKAAVPQKKIPEAVPPKPESPPPEVYEEPAEEIVPEEPPEEVVEEPEPAPPPKVTVPPKKPVPEKKAPPAVVKKPEPPPAKAPEVPKEAPPEKKVPSVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVVEEKPVIEEKPAIPVAEKVESPPTEVYEEPEEVAAQE------EEPAPVVEEEEYEAPPPPAPVPEEPKKVVPEKKYPVIKKPEPPPPKVPEVSKKPAPMKKVPVVKKPEPPEAEVPEVPKKLAPVKKEPVPVTKKPEVLPEKVPEAPKKITPEKRESAPVPEEPEAPPAPVEEIPEETIYEEKATITIGRKETPPVEEREIERFIQPEEPGMEPQPEETPVQEPEPEKKVIEKPKLKPRPPIRAPSPPKEDVKEKIFQLKAVSKKKVPEKPEVVEKVEPTPLKE----------------------------------------------------PPPPPKAVEVEAPPEPKPKERKVPEPTKVPEIKPAIPLPGPEPKPKPEPEVKTMKAPPIEPAPTPIAAPVTAPVVGKKAEAK-PKDEAAKPKGPIKGVAKKTPSPIEAERKKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIVLTEAESVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEIIREWLVKPIRDQHVKPKGTAVFTCHIAKDTPNIKWFKGYDEIPLEPNDKTEILKEGNHLILKVKNAMPEDIDEYAVEIEGKRYPAKLTLGERDVELLKPIEDVTIYEKESASFDAEISEEDIPGEWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQACNAVTTAILTVKEIELDFAVPLKDVTVPEKRQARFECVLTREANVIWSKGPDIIKASDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSAQLFVTGIRLKFISPLEDQTVKEGQ--TATFVCELSHEKMHVVWFKNDVKLHTTRTVLMSSEGKTYKLEIRETTLDDISQIKAQVKNLSSTANLKVLEADPYFTVKLHDKTGVEKDEIILKCEVSKDVPVKWFKDGEEIVPSPKHSVKTDGLRRILKIKKAELKDKGEYTCDCGTDTTKANVTVEARLIKVEKPLYGVEVFVGETARFEIELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKHVLVLYNCQLDMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEIAGDDRFELIKDGTR--HSLVIKSAAFEDEAKYMFEAEDKRTSGKLIIEGIRLKFLTPLKDVTAKERENAVFTVELSHDNIPVSWFKNDQRLHTSKRVSMHDEGKTHSITFKDLSIDDTSQIRVEAMGISSEAKLTVLEGDPYFTGKLQDYTGVEKDEVVLQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDQTSGKLDIEDREIKLVRPLYSVEVMETETARFETEISEDDIHANWKLKGEALLQTPECEIKEEGKIHVLILHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPNDKVVTRSEGRVHTLTLRDVKLEDAGEVQLTAKDFKTQANLFVKEPPVEFTKPLEDQTVEEEATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLIIHGCTPEDIKTYTCDAKDFKTSCNLNVIPPHVEFLRPLTDLQVKEKETARFECEISKENVKVQWFKDGAEIKKGKKYDIISKGAVRILVINKCLLNDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLANLEVSEGDTIKLVCEVSKPGAEVTWYKGDEEVIETGRFEILTDGRKRILIIQNAQLEDAGSYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCTISKESFEVQWKRDDQTLESGDKYDIIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVPLKDTKVKEQQEAVFNCEVNTEGAKAKWFRNDEAIFDSSKYIILQKDLVYTLRIRDARLDDQANFSVSLTNHRGENVKSAANLIVEEEDLRIIEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVAFDNRISYRIDKYKHSLIIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLEDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVIFLAELNKDKVEVQWLRNNMIVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAPPKIKTSDQDLVVDAGQPLTMVVPYDAYPKAEAEWFKENEPLSTKTVDTTAEQTSFRILEAKKEDKGRYKIVLQNKHGKAEGFINLQVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLVTDRADSCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDSPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLSASEQTQSSVQLTWEPPLKDGGSPILGYIIERQEEGKDNWIRCNMKPVPELTYKVTGLQKGNKYLYRVSAENAAGVSDPSEILGPLTADDASVEPTMDLSAFKDGLEVIVPNPIKILVPSTGYPRPKATWTFGDQVLEAGDRVKIKTISAYAELIISPSERPDKGIYTLTLENPVKSISGEIDVNVIARPSAPKELKFSDVTKDSVHLTWEPPDDDGGSPLTGYVVEKRDMSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYTDEPVNMSAPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVEKCPRGSDKWVACGEPVPDTKMEVTGLEEGKWYAYRVKALNRQGASKPSKPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADTLLRPD-QRITIENVPKKSTVTITDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERKATDSDVWHKLSSTVKDTNFKATKLTPNKEYIFRVAAENMYGVGEPVQATPIIAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSRSTEPILIKDPIDPPWPPGKPTVKDIGKTSLVLNWTKPEHDGGAKIESYVIEMLKTGTDDWVRVAEG-VPTTEHLLTGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIGDSVLAKDTFTTPGPPYALTVVDVTKRHVDLKWEPPKNDGGRPIQRYIIEKKEKLGTRWVKAGKTSGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPVGPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAVGVSDPSEISENVVAKDPDCKPTIDLETHDIVVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVHADAGVYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGSPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKIGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAKAMTITWKPPLYDGGSKIMGYIIEKLAKGEDRWKRCNEHLVPVLTYTAKGLEEGKEYQFRVRAENAAGIGEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDATISGSPYPTITWIKDENVIVPEEIKKRVAPPVRRKKGEAEEEEPFTLPLTERLSINNSKQGESQLRVRDSLRPDHGQYMIKVENDHGVAKAPCTVSVLDTPGPPINFVFEDIRKDSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVITSTLRNCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLLAKDPFEPPDAPDKPIVDDVTSNSMVVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKALLSSLKTKVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTARDPISPPGPPVPRVADTSSTTIELEWEPPAFNGGGEIMGYFVDKQLVGTNEWSRCTEKMVKVRQFTVKEIREGADYKLRVSAVNAAGEGPPGETEPVTVAEPQEPPTVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTIEEGE--LDKERVVIENVGTKSELIIKNALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPADDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLIEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSDGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVDNLDEHQMYEFRVKAVNDIGESEPSLPLNVVIQDDEVPPTIKLRLAVRGDTIKVKAGEPVNIPADVTGLPMPKIEWSKNEKVIEKPTDALNITKEEVSRSEAKTELSIPKAVREDKGTYTITASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYIIDKRDASRKKSEWEEVTNTAVERRYGIWKLIPNGQYEFRVRAVNKYGTSDECKSDKVVIQDPYRLPGPPGKPKVLERTKGSMLVSWTPPLDNGGSPITGYWLEKREEGGAYWSRVSRAPITKVGLKGVEFSVPRLIEGVKYQFRAMAINAAGIGPPSEPSDPAVAGDPIYPPGPPSCPEVKDKTKSSISLAWKPPAKDGGSPIKGYIVEMQEEGTTDWKKVNEPDKLLTACECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEVPEVFIDIGAQDCLICKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGIHDIPEDAQLETAENSSVIVIPECTRAHSGKYSITAKNKAGQKTANCRVKVMDAPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKKTIDGKAWTKVNPNCGSTAFVVPDLISEQQYFFRVRAENRFGIGPPAETIQRTTARDPIYPPDLPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGKKKEAWRQCNRRDVEELEFTVEDLVEGGEYEFRVKAVNEAGVSKPSATVGPVTVKDQTCPPSIELKEFMEVEEGTDVNIVAKIKGVPFPTLTWFKAPPKKPDSKEPVVYDTHVNKQVVDDTCTLVIPQSRRSDTGLYSITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESISADQMTLSWLPPKDDGGSKITNYVIEKREANRKTWVRVSSEPKECMYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPVTARDPVAPPGPPFPKVTDWTKSSVDLEWSPPLKDGGSKITGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGVGEPGEVTDIIEMKDRIVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERALPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEGGERKKTIIVDVLDVPGPVGIPFLSDNLTNDSCKLTWFSPEDDGGSPITNYVIQKREADRRAWTPVTYTVTRQNATVQGLIQGKSYFFRIAAENSIGMGPFVETPNALVIRDPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLDLDFRDKLTVRVGEAFALTGRYSGKPKPKVDWFKDEADVLEDDRTHIKTTPTTLALEKTKAKRSDSGRYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVVFDEVTKEYMVISWKPPLDDGGSEITNYIIEKKELGKDIWMPVTSASAKTTCKVPKLLEGKDYIFRIHAENLYGISDPLVSDSMKARDRFRVPDAPEQPVVTEVTKDSALVTWNKPNDGGKPITNYILEKRETMSKRWVRVTKEPIHPYTKYRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFARDPIAKPSPPINPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNEAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDREAPTKAQIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVVTNYVVERKDVATAQWSPLSTTSKKKSHMAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGAKDWIKFKTVKNLECVVTGLQQGKTYRFRVKAENIIGLGLPDTTIPIECQEKLEPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWATDGTEITTDDHYTVETDSFSSVLTIKNCLRKDTGEYQLTVSNAAGTKTVAVHLTVLDVPGPPTGPINILDVTPEYMTISWQPPKDDGGSPVINYIVEKQDTRKGTWGVVSAGSSKLKLKVPHLQKGCEYVFRVKAENKMGVGPPLDSIPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYVERREITGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSNPSPSSDPIKACRPIKPPGPPINPKLKDKTKESADLVWTKPLSDGGSPILGYVVECQKPGTTQWDRINKDELIRQCAFRVPGLIEGNEYRFRIRAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWSKEGKVLVKDKRVDLIHDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVSNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSADWERVHKGSIKETHYMVDKCVENQIYEFRVQTKNEGGESDWVRTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTSAESSKFSLTKAKRSDGGKYVVTATNPAGSFVAYATVNVLDKPGPVRNLKIADVSSDRCTIRWDPPEDDGGCEIQNYILEKCESKRMVWSTYSANVLTPGATVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDRPGRPDPPEVTKVSKEEMTVVWNAPEYDGGKSITGYYLEKKEKHAVRWVPVNKSAIPERRLKVQNLLPGHEYQFRVKAENEVGIGEPSLPSRPVVAKDPIEPPGPPTNFKVVDTTKNSITLAWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRMEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIRPKEILEPPEIDLDASMRKLVVVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVKVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSPVTHYIVEKREAERKTWSTVTPEVKKTSFNVTNLVPGNEYFFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKVEVTEMTKNSATLAWLPPLRDGGAKIDGYIISYREEDQPADRWTEYSVVKDLSLIITGLKEGKKYKFRVAARNAVGVSMPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRVEAHVYGKPNPICKWKKGEDDVVTSSHLAIHKADSSSVLIIKDVTRKDSGYYSLTAENSSGTDTQKIKVTVMDAPGPPQPPFDISEIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMLAKFPFDVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPITGYLIERKERNSLLWVKANDTIVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVVDVTKNSASLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTTPHQIPLEEYTATGLEENAQYQFRAIAKTAVNISQPSEPSDPVTILAENVPPRIELSVEMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDSTPIKQTEGVKMAMKRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYADRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCTVEKLIEGHEYQFRICAENKYGVGDPIFTEPVIAKNPYDPPGRCDPPVISNITKDHMTVSWKAPADDGGSPITGYLVEKRETQAVNWTKVNRKPVIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAVYAQDPLYPPGPPAFPKVYDTTRSSVSLSWGKPAFDGGSPIIGYLVEVKRADSDHWVRCNLPEKLQKTRFEVTGLMENTEYQFRVYAVNKIGYSDPSDVPDKHCPKDILIPPEGELDAELRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRERIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYITWDPPIIDGGSPIINYVVEKRDAERKSWSTVTTECPKTSFRVSNLEEGKSYFFRVFAENEYGIGDPGETRDAVKASETPGPVVDLKVLAVTKSSCTIGWKKPRSDGGSRITGYVVDFLTEENKWQRVMKSLSLQYSTKDLKEGKEYTFRVSAENENGEGTPSEIMVVAKDDVVAPDLDLKDLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESTAVNTTLVVYDCQKSDAGKYTITLKNVAGTKEGTLSIKVVGKPGIPTGPIKFDEVTAEAMTLKWGPPKDDGGSEITNYVLEKRDSVNNKWVTCASAVQKTTFRVTRLHEGIEYTFRVSAENKYGVGEGLKSEPIVAKHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHIEFKERNSLLWKRANKTPIRMKDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVISVTRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPDCAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTGTIICKDEYEAPTIVLDPTIKDGLTVKAGDSIVLSAISILGKPLPKSSWSKAGKDIRPSDIAQITSTPTSSMLTVKYATRKDAGEYTITATNPFGTKEEHVKVSVLDVPGPPGPIEISNVSAEKATLTWTPPLEDGGSPIKAYVLEKRETSRLLWTVVSEDIQACRHVVTKLIQGNEYLFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPGKPEISNVTKNTATVSWKRPIDDGGSEITGYHVERREKKGLRWVRATKTPVSDLRCKVTGLQEGNTYEFRVSAENRAGIGPPSDASNPVLMKDVAYPPGPPSNAHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDDAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAVNDAGVGEPAVIPNVEIVEKETAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDN--INLKHRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTVTTKCHKCTYKVTGLTEGCEYFFRVMAENEYGIGEPTETTEPVRASEAPLPPDSLNIMDITKNTVSLAWPKPRHDGGSKITGYVIEAQRKGSDQWTHISTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIARAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNVENTATSTILNINECVRSDSGAYPLTAKNTVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWEPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGVEYQFRVKAQNRYGVGPGITSASVVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHIERKERNGILWQTVSKALVPGNIFKSTGLTDGIAYEFRVIAENMAGKSKPSKPSEPTFALDPIDPPGKPVPLNITRHTVALKWAKPEYTGGFKITSYVVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDLEAPRIMVDVKFKDTITLKAGEAFKLEADVSGRPPPTMEWAKDGKELEG-TGKLEIKIADFSTHLINKDSSRTDSGAYILTATNPGGFAKHIFNVKVLDRPGPPEGPLAVSDVTSEKCVLSWLPPLDDGGAKIDHYIVQKRETSRLAWTNVATEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE-PVLAVDPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWVKCNKKALTDLRFKVSGLTEGHEYEFRIMAENAAGVSAPSATSPFYKACDSVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQVVTPPAGLKATSYTITNLIENQEYKIRIYAMNSEGLGEPALVPGTPKAEERMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWAREHGESLDKASIESTSSYTLLVVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQNLKIKEVTKTSVTLTWEPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKIDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQSKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKIDVPFIGRPTPTVTWHKDDVPLKQTTRVNAESTENNSLLTIKEACREDVGHYTVKLTNSAGEATETLNVIVLDKPGPPTGPVKMDEVTADSVTLSWEPPKYDGGSSINNYIVEKRDTSTTAWQIVSATVARTTIKASRLKTGCEYQFRIAAENRYGKSTYLNSE-PVIAQYPFKVPGPPGTPFVTLASKDSMEVQWHEPVSDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGIEYEFRVSAENIVGIGKPSKPSECYAAHDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYVVEKKELPDGRWMKASFTNIIDTQFEVTGLIEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVEPPRISMDPKYKDTVVVQAGESFKIDADIYGKPIPTTQWVKGDQELSSTARLEIKTTDFATSLSVKDAVRVDSGNYILKAKNVAGEKSVTVNVKVLDRPGPPEGPVAISGVTAEKCMLAWKPPLQDGGSDIINYIVERRETSRLVWTLVDANVQTLSCKVTKLLEGNEYIFRIMAVNKYGVGEPLESEPLIAKNPFVVPDAPKAPEVTAVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLLENHNYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVMDVTRSSVFLSWTKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNLEVEKLLEKHEYNFRICAINKAGVGEHADVPGPVMVEEKLEAPDIDLDLELRKVINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPARTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKNTDKWSECARVKSLEAVITSLTQGEEYLFRVIAVNEKGRSDPRSLAVPITAKDLVIEPDVRPAFSSYSVQVGQDLKIEVPISGRPKPSISWTKDGAPLKQTTRINVIDSLDLTTLSIKETHKDDGGHYGITVANVVGQKTAAIEIITLDKPDPPKGPVKFDEVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESEPIVAQYPYKEPGPPGTPFVTAVSKDSMVVQWHEPINNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKALNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEAIIVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPEGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCTLAWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYIFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNVHIVDTTKNSITLAWGKPIYDGGSDILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLIEHQEYKIRVCALNKVGLGEAASVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSKEEGEFTDKVQIEKGINFTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSVLLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPAETSDAVKASEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRILGYVVEMQPKGTEKWSVVAESKVCSAVVSGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSFKLPFNTYSVQAGEDLKIEIPVIGRPRPKISWVKDGEPLRQTTRVNVEETATSTILHIKESSKDDFGKYSVTATNNAGTATENLSVIVLEKPGPPVGPVKFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTNWQMVSATVARTTIKVSKLKTGTEYQFRIFAENRYGKSTPLDSKPVVVQYPFKEPGPPGTPFVTSVSKDQMLVQWHEPVNDGGSKVIGYHLEQKEKNSILWVKLNKIPIQDTKFKTTGLDEGLEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIITRNSVTLKWKKPTYDGGSKITGYIVEKKDLPDGRWMKASFTNVVETEFTVTGLVEDQRYEFRVIARNAADNFSEPSESSGAITARDEIDAPNASLDPKYRDVIIVRAGETFVLEADIRGKPIPDIVWSKDGNELEETAARMEIKSTLQKTTLTVKDCIRTDGGQYTLKLSNVGGTKTIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGASISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGVGEPLESEPVIACNPYKLPGPPSTPEASAITKDSMVLTWTRPVDDGGAEIEGYILEKRDKEGIRWTKCNKKTLTDLRFRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWNKPIYDGGAPVRGYVIELKEAAADEWTTCTPPSGLQGKQFTVTKLKENTEYNFRICAFNTEGVGEPATIPGSVVAQERMEAPEIELDADLRKVVTLRASATLRLFVTIKGRPEPEVKWEKAEGILTERAQIEVTSSYTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTVREVKKDSVTLSWEPPLIDGGAKVTNYIVEKRETTRKAYATITNNCTKTTFKIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVVAKDIEIKPSVELPFNTFNVKANDQLKIDIPFKGRPQATVAWKKDGQVLRETTRVNVSSSKIVTTLSIKEASREDVGTYELCVSNTAGSITVPITVIVLDRPGPPGPIRIDEVSCDNVSISWTPPEYDGGCQISNYIVEKRETTSTTWQVVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMVVSWQVPVNDGGSQVIGYHLEYKERSSILWSKANKVLIADTQMKVSGLDEGLLYEYRVYAENIAGIGKCSKACEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPRYDGGAKITGYIVERRELPDGRWLKCNFTNVQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPITVKDDVEAPRIMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGVEIEERAKTEIVSTDSNTTLTVKDCVRRDTGQYVLTLKNVAGTRTMAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSRLAWTICEAELRTTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESV-AVKALDPFTTPSPPTSLEITSVTKDSMTLCWSRPETDGGSDISGYIIERREKNSLRWMRVNKKPVYDLRVKSTGLREGCEYEYRVFAENAAGLSLPSDTSPLVRAEDPVFLPSPPSKPKIVDSGKTTITIGWVKPLFDGGAPITGYTVEYKKSEETDWKVAIQSFRGTEYTMSGLTTGAEYVFRVRSLNKVGASDPSDITDPQVAKEREEEPAFDVDSEMRKTLTVKAGSSFTMTVPFRGRPIPNVSWSKPDTDLRTRAYIDSTDSRTSLTIENANRNDSGKYTLTIQNVLSAASMTFVVKVLDSPGPPANITVREVTKETAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCSRLSYKVTNLQEGAVYYFRVSGENEFGVGVPAETKEGVKITEKPSPPEKLGVTSVSKDSVSLSWLKPEHDGGSRILHYVVEALEKGQKNWVKCAVVKTTHHVVSGLREGHEYFFRVFAENQAGLSDPRELLLPVLIKDHLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGKYEITAANSSGTTKTFINIIVLDRPGPPTGPVAISDITEESVTLKWEPPKYDGGSHVTNYIVLKRETSTAVWTEVSATVARTMIKVMKLTTGEEYQFRIKAENRFGISDHIDSACVVVKLPYTTPGPPSTPWVSNVTRESITVGWHEPVSNGGSAVIGYHLEMKDRNSILWQKANKMIIRTTHFKVTTISAGLIYEFRVYAENAAGIGKPSHSSEPVLAIDACEPPRNVRITDISKNSVNLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVIETQFTVSGLTQNSQYEFRVFARNAVGSVSNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPEPTIEWYKDDKELQTNALVCVENSTDLASILIKDANRLNSGSYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVAENLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESEPVVAKNSFVTPGPPSIPEVTKITKNSMTVVWNRPTVDGGSEINGYFLEKRDKKSLAWLKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGMGPFSEPSDFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSDVTGYVVEMRQGEEEEWTIVSTKGEARTTEYVVSNLKPGVNYYFQVSAVNCAGQGEPITMTEPVQAKDILEEPEIDLDVALRTSVIAKAGEDVQLLIPFKGRPPPTVTWRKDEKNLGSDARYSIQNTDSSSLLVIPQVTRNDTGKYILTIENGVGQPKSSTVSVKVLDTPAACQKLQVKHVSLGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSIVSHKCSGTSFKVMDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVVLSWTKPDFDGGSIITDYLVERKGKGEQAWSHAGISKTCEIEIGQLKEQSVLEFRVSARNEKGQSDPVTIGPLTVKELVITPEVDLSEIPGAQISVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEYVRFSKTENKITLSIKNVKKENGGKYTVILDNAVCRNSFPITIITLGPPSKPKGPIRFDEIKADSAIMSWDIPEDDGGGEITCYSIEKREASQTNWKMVCSSVARTTFKVSNLVKDSEYQFRVRAENRYGVSEPLVSNVIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQRVNTSPISGREYRATGLIEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVAYSIEKRQGSDRWVRCNFTDVSECQYTVSGLSPGDRYEFRIIARNAVGTISPPSQSSGLIMTRDENVPPTVEFGPEYFDGLVIKSGDSLRIKALVQGRPVPRVTWFKDGVEIERRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNVSGSTKAEITVKVQDTPGKVVGPIRFTNITGEKMTLWWEAPLNDGCAPVTHYIIEKRETSRLAWALIEDHCEAQSYTAIKLITGNEYQFRVSAVNKFGVGRPLESDPVVAQIQYTIPDAPGIPEPSNVTGNSITLTWTRPESDGGNEIQHYILERREKKSTRWVKVISKRPISETRFKVTGLVEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPSAPAVVKVTDTSKTTVSLEWARPVFDGGMEIIGYIIEMCKADLGDWHKVNTEPCVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLSAPELDIDANFKQTHIVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSIRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGRKSITFTVKVLDSPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVIEKREASRRSWQVVSEKCTRQILKVSDLTEGVPYYFRVSAENEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPEHDGGSRITSYLLEMRQKGSDFWVEAGHTKQLTFTVERLVENTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSTFTIDVPISGRPAPKVTWKLEEMRLKETDRMSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFTITVVVIGRPGPVTGPIEVSSVSAESCVLSWSEPKDDGGTEITNYIVEKRESGTTAWQLINSSVKRTQIKVTHLTKYKEYCFRVSSENRFGVSKPLESVPIVAEHPFVPPSAPTRPEVYYVSANAMSIRWEEPYHDGGSKIVGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDPPGRPEVTDVTRSTVSLVWSAPMYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGIISKGSESTGPVTCRDEYAPPKAELDARLQGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKYCDRSDSGKYTLTVKNASGTKSVSVMVKVLDSPGPCGKLTVSRVTEEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEAECLTLSYVVTRLIKNNEYTFRVRAVNKYGLGVPIESEPIVARNSFTIPSQPGIPEGVGAGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNSAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKSSISLAWTKPMYDGGTDIIGYVLEMQEKDTDQWCRVHTNTTIRNNEFTVPDLKMGQKYSFRVAAVNAKGMSDYSETTAEIEPVERLEIPDLELADDLKKTVIIRAGASLRLMVSVSGRPSPVITWSKKGIDLANRAIIDNTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVNVKEVSRDSVTITWEIPTIDGGAPVNNYIIEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPTKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLDHTVISLNEGEQYLFRVRAQNEKGVSEPREIVTPVTVQDLRVLPTIDLSTMPQKTIHVPAGRPIELVIPITGRPPPTASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYMLELKNVTGTTSETIKVVILDKPGPPIGPIKIDEVDATSVTISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRPTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSISIPGPPETLQIFDISRDGMTLTWYPPEDDGGSQVTGYIIERKEVRADRWVRVNKVPVTMTRYRSTGLIEGLEYEHRVTAINARGTGKPSRPSKPTVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQREWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGVFVRQGGVIRLTIPIKGKPFPICKWTKEGQDVSKRAMIATSETHTELVIKEADRNDSGTYDLVLENKCGKKTVYIKVKVIGSPNTPEGPLEYDDIQTRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVIPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVILQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDRQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSVKTKLTSG-EAPGVRKEMADVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELVQSR-KYKMSSDGRTHTLTVMTEEQEDEGVYTCVATNEVGEVETSSKLLLQAAPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWYHGQKLLQNSESITIENTEHYTHLVMKNVQ--RKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSVVISWKAPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISEPLEVASVVIIKSPFEKPSVPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWIAVTTEEIRETVFSVQNLIEGLEYEFRVKCENLGGESEWSETSEPVTPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRVQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKVTNYIVEKCATTAERWLRVGQARETRYTVVNLFGKTSYQFRVIAENKFGLSKPSEPSEPTVTKEDKTR-----------------------AMNYDEEVDETREVTMTKASHSKTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTFMAKFVKVKG-TDQVLVKKEISILNIARHRNILYLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREVVSYVRQVCEALEFLHSQNIGHFDIRPENIIYQTRKNSIIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQHDVVSSATDMWSLGTLVYVLLSGINPFLAETNQQMIENIMNAEYTFDEEAFQEISLEAMDFIDRLLVKERKSRMTASEALKHPWLKQRMDRVSTKVIRTLRHRRYYHTLIKKDLNMVVSAARISCGGAIRSQRGVSVAKVKVASIEIGPVSGQIMHAIGEEGGYVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRR-TKKVKRRTDAMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPRVTWYKSGQKIKPGDDDKKYTFESDKGLYQLTINSVTTDDDAEYAVVARNKHGEDSCKAKLTVTLHPPPTETTLRPMFKRLLANAECHEGQSVCFEIRVSGIPAPTLKWEKDGQPLSLGPHIEIVHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVDRLRYVKQEFQTKEERERHVQKQIDKTLRMAEILSGTETVPLTPVAQEALREAAILYKPAVSTKTVKGEYRLETEEKKEERKLRMPYEVPEPRRFKQATVEEDQRIKQFVPMSDMKWYKKIRDQYEMPGKLDRVVQKRPKRIRLSRWEQFYVMPLPRITDQYRPKWRIPKLTQDDLEMVRPARRRTPSPDYDLYYYRRRRRSLGDISDEELLLPIDDYLAMKRTEEERLRLEEELELGFSASPPSRSPPRFELSSLRYSSPPAHVKVEDRRRDFRYSTYHIPTREETSTSYAELRERHAQASYRQPKLRQRIMAEKEEEELLRPVTTTQRLSEYKSELDYMSKEEKSKKKSKRQRQVTEITEIEEEYEISRRAQRESSSSVSRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCQTEDSGTYRAVCTNYKGEASDYATLDVTGGHYTTYASQRRDEEVPKSVFPELTKTEAYAISSFKRTSEMEAASSVREVKSQMTETRESLSSYEHHVSAEMKSAASEEKSLEEKATVRKIKTTLAARILTKPRSITVHEGESARFSCDTDGEPVPTVTWLRGGQVVSTSARHQVTTAKYKSTFEISSVQASDEGNYSVVVENTDGKQEAQFTLTVQKAKAVEKAVTSPPRVKSPEPRVKSPETVKSPKRVKSPELVASHPKAVSPTETKPT--EKGQQLPVPAPPKITQSLKAEASRDIAKLTCAVESSALCAKEVAWYKDGKKLKENGHFQFHYSADGTYELKIHNLSESDCGEYVCEVSGEGGTSKTSFQFTGQSFKSIHEQVSSTTETKKSVQKTAESAEAKKATQKTAESAEAKKATQKTAESAEAKKPAQKTAESAEAKKPAQKTAEPTEAKKQEPIAPESVSSKPVIVTGLRDTTVSSDSVAKFVIKVTGEPQPTVTWTKDGKAIAQSSKYKLSNDKEEFILEILKTETSDGGLYSCTVANSAGSVSSSCKLTIKAVKDTEAQKVSTQKTSEVTAKKKESVQQEISQKVLTSEEIKMSEVKSHETLAIKEEASKVLIAEEVKKSAAASLEKSIVHEEVTKTSQASEEVKTHAEIKALSTQMNITSGQRVTLKANIAGATDVKWVLNGTELSNSEEYRYGVSGSDQTLTIKQASHRDEGILTCIGK--TSQGVVKCQFDLTLSKELSDAPSFISQPRSQNINEGQNVLFSCEISGEPSPEIEWFKNNLPISISSNISVSRSRNMYTLEIRNASVSDSGKYTVKAKNFRGQCSATASLTVLPLVEEPPREVVLKTSGDMSLQGSFSSQSVQMSASKQEASFSSFSSGSAS-MTEMKFASMSAQSMSSVQESFVEMSSSSFMGKSSMTQLESSTSRMLKAGGRGIPPKIEALPSDISIAEGKVLTVACAFTGEPTPEITWSCGGRRIQSQEQQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNINIRSM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ASS6-1", "uniprot_id": "TITIN_MOUSE", "id": "A2ASS6-1", "name": "Titin", "aln": "MTTQAPMFTQPLQSVVVLEGSTATFEAHVSGSPVPEVSWFRDGQVISTSTLPGVQISFSDGRARLMIPAVTKANSGRYSLRATNGSGQATSTAELLVTAETAPPNFSQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELVVQGEEVVPAKKTKTIVSTAQISETRQTRIEKKIEAHFDARSIATVEMVIDGAT-GQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAGRISTSPIRSVKSPLLIRKTQTTTMATGPEVPPPWKQEGYVASSTEAEMRETTMTSSTQIRREERWEGRYGVQEQVTISGAAAAAASASVSSSFTAGAITTGTKEVKQETDKSAAVATVVAAVDMARVREPAISAVEQTAQRTTTTAVHIQPAQEQARKEAEKTAVTKVVVAADKAKEQELKSRTREVMVTTQEQTHISHEQIRKETEKAFVPKVVISATKAKEQETRITGEITTKQEQKRITQETIRQETEEIAASMVVVATAKSTKLEAAVGVQEETAIQQDQMHLTHEQMMKETRKTVVPKVIVATPKIKEQDLVSRSREAITTKRDQVQITQEKKRKEVETTALSTIAVATAKAKEQETVLRSREAMATRQEHIQVTHGQVGVGKKAEAVATVVAAVDQARVREPREPTHVEESHSQQTTLEYGYKEHISTTKVPEQPRRPASEPHVVPQAVKPAVIQAPSETHIKTTDQMGMHISSQVKKTTDISTERLVHVDKRPRTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSATSSTQKITKSVKAPTVKPGETRVRAEPTPSPQFPFADMPPPDTYKSQAGIEVKKEVGVSISGSTVREEHFEVLRGREAKVTETARVPAPAEVPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPKVTWYREDYQIESSIDFQITFQGGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFDKETT-LTEKFATEEKRFVESRDVVMTDTSITEEQAGPGEPAAPFFISKPVVQKLVEGGSVVFECQIGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECRLVISMTFADDAGEYTIVIRNKHGETSASASLLEEADYEALVKTQQEMLYQTQMSTFIQEPKVGEIAPGFAYSEYEKEYEKEQALIRKKMAKDTVMVRTFVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAIESGFDIRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIRHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPFSAPTYMPTPEAVSRIRSVSPRSLSRSPIRMSPAMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPASFKCLEGQTARFDLKVVGRPMPETFWFHNGQQIVNDYTHKVVIKEDGTQSLIIVPASPSDSGEWTVVAQNRAGKSTISVTLTVEAVEHQIKPAFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPRIRIEGTRGEAALKIDSIISQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGAAYSRDSGVITCRATNKYGTDHTSATLIVKDEKSLVEESQLPDGKKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLFPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVTEHKVKLEIQQREDFRSVLRRAPEPKPEFHVHEPGKLQFEVQKVDRPVDTSETKEVVKLKRAERITHEKVSEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLKKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPERIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFIKVKWYKDGIEVHAGDKYRMHSDRKVHFLSVLTIDTSDAEDYSCVLVEDENIKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIISPENIEGKWYHNDVELKSNGKYSITSRRGRQNLTVKDVTKEDQGEYSFVVDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLENVEGVWMKDGQEVQHSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGNVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQSIVKGTKQRLVINRTHASDEGPYKLMVGRVETSCNLSVEKIKIIRGLRDLTCTETQNVVFEVELSHSGIDVVWNFKGKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGEYAFYAGENTTSGKLTVAGGAISTPLTDQTVAESQEAVFECEVANPESEGEWLKDGKHLALSNNFRGESDGHKRRLVIAAAKLDDAGEYTYKVATSKTSAKLKVEAVKIKKTLRNLTVTETQDAVFSVELTHPDVKGVQWIKNGVVLDSNDKYEISVKGTLYSLKIKNCAMADESVYGFKLGRLGASARLHVETVKIIKKPKDVTALENATVTFEVSVSHDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLMLQSISPSDAGEYTAMVGQLECKAKLFVETLHITKTMKSIEVPETKAASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDRCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDGQELQIADRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNMSTANLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHQYVVERRIHRMFISETRHSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIVTPLQDTVTSEGRPARFQCQVSGTDLKVSWYCKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYAFVANNAVGQVSSTATLRLEAPESILHERIGQQIEMEMKEIASLLSAEEDFQTYSSDLRLPNANETLELLSEPPARSTQFDSRQEGAAPVFIREISDVEISVEDVAKLSVTVTGCPKPKIQWFFNGMLLTPSADYKFVFDGDTHSLIILFTRFQDEGEYTCLASNEYGKAVCSAHLRISPRGE--RSTEMESGEKKALEKPKGPCPPYFFKELKPVHCGPGIPAVFEYSVHGEPAPTVLWFKEDMPLYTSVCYTIIHSPDGSGTFIVNDPQRGDSGLYLCKAQNLWGESTCAAELLVLPEDTDVPDASCKEESTLGVPGDFLETSARGPLVQGVDSRQEITAFAEGTISKAALIAEETLQLSYERSVDDSEVGTGVTIGAQKLPPVVLS---TPQGTGELPSIDGAVHTQPGRGPPPTLNLQAVQAQTTLPKEATLQFEEP---------EGVFPGASSAAQVSPVTIKPLITLTAEPKGNYPQSSTAAPDHALLSSVAAETLQLGEKKIPEVDK----------AQRALLLSQSLAEGCVESLEVPDVAVSNMRSEPQVPFQHTCTEG-KILMASADTLKSTGQDVALRTEEGKSLSFPLALEEKQVLLKEEQSEVVAVPTSQTSKSEKEPEAIKGVKEVREQELLSKETLFPSMPEEQRLHLKTQVRRALQAAVAREQANLFSEWLRNIDKVEVTAVNFTQEPKRILCTYLITSVSSLTEELTVTIEDIDPQMANLETGLKDALCSIVCEERNILMAEDPRIHEEDKIDVQGGRDHLSDAQKVETVIEAEADSKYLVSKEEVSWSKVESQLKDGDTNEVPQ-------------------AETLKLAEESGTQKTSTEMSQEEAEGTLADLCPAVLKHLVDTISEEGDTVHLTSSISNAKEVHWYFKGNLVPSDGKFKCLKEQNAYTLVIEAVKTEDEG-EYVCEASNDSGKAKTSAKLTVGERAAPVIKRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSNYVSSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKALTTFVGKAAKFLCTVSGTPVIEIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKASNKFGADICQAELTIIDKPHFIKELEAVQSAINKKIHLECQVDEDRKVTITWSKDGQKLPAGKDYKIYFEDKIASLEIPLAKLKDSGTYTCTASNEAGSSSSSAAVAVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMSFVNSEAILDITDVKVDDSGTYSCEATNDVGSDSCSTEVVIKEPPSFIKTLEPADIVRGANALLQCEIAGTGPFEVNWFKDKKQIRSSKKYRLFTQKTFVYLEISSFNSADVGDYECVVANEVGKCGCVATHLLKEPPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVLTIPDVQISLGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVSGTPELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKELTASDRYQIAFVEGTASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSRDVLPGSAVCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSESSLELYAVKTSDSGTYTCKVSNVAGSVECSADLFVKEPATFIEKLEPSQLLKKGDGTQLACKVTGTPPIKITWFANDRELRESSKHKMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHCTGIVIVKESPYFTKEFKSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFLQDQLVSLQVLKFVAADAGEYQCRVTNEVGSSTCSARVTLREPPSFIKKIEATSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATIMEEAVSIDVTQGDPATLQVKFSGTKEISAKWFKDGQELTLGPKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKLRKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASDKHKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHSQCSGHLTVKEPPYFVEKPQSQDVNPGTRVQLKALVGGTAPMTIKWFKDNKELHPGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTTSSKATIFVKEPPQFIKKPSPVLVLRNGQSTTFECQVTGTPEIRVSWYLDGNEITDLRKYGISFVDGLATFQISNARVENSGTYVCEARNDAGTASCSIELKVKEPPIFIRELEPVEVVKDSDVELECEVMGTTPFEVTWLKNNKEIRSGKKYTMSEKMSVFYLHITKCDPSDVGEYQCIIANEGGSCACSARVALKEPPSFIKKIENVTTVLKSSATFQSTVAGSPPISITWLKDDQILEENDNVHISFEDSVATLQVRSVDNGHSGRYTCQAKNESGIERCYAFLLVQEPAQIIEKAKSVDVTEKDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVKEPPSFLVKPERQQAIPDSTVEFKAVLKGTPPFKIKWLKDDVELVSGPKCFIGLEGSTSFLNLYSVDSSKTGQYTCQVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIIKAGDSARLECKITGSPEIQVVWYRNEHELTASDKYQMTFIDSVAVIQMNSLGTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNTEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKVASKNFHASIHILNVESTDIGEYHCKAQNEVGSDACVCAVKLKEPPKFISKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRISFVNNVATLQFAKVEPANAGKYICQVKNDGGVRENMATLTVLEPAVIIEKAGSMTVTVGETCALECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLKDTGGVLGTSCILECKVAGSSPISIAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAGSDECRALLTVQEPPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGNRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPATFVKKLSDHSVEPGKSIILEGTYTGTLPISVTWKKDGVSITPSERCNIVTTEKTCILEILSSTKGDAGHYSCEIENEAGRDACDALVSTLEPPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWFKGDTKLRSTPEYRTYFTNNVATLVFNKVSINDSGEYTCMAENSIGTAASKTIFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQMSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESWKYNMSFVNSVALLTINEASAEDTGDYICEAHNGVGDASCSTALKVKAPPVFTQKPPPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKITSKNFDTSLHIFNLEAPDIGEYHCKATNEVGSDTCACTVKFKEPPRFVKKLSDASTLIGDPVELQAVVEGFQPISVVWLKDKGEVIRESENVRISFVDNIATLQLGSPEASQSGKYVCQIKNDAGMRECSAVLTVLEPATIVEKPEPMTVTTGNPFTLECVVAGTPELSAKWFKDGRELSSGSRHHITFVRNLASLKIPSAEMNDKGLYTFEVENRVGKSSCTVSVHVSDRVVPPSFVRRLKDTSATLGASVVLECRVSGSAPISVGWFLDGNEIISSPKCQSSFADNVCTLTLSSLEPSDTGAYTCVAANVAGQDESSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVSGEACTISLEDFVTELELLEVEPGQSGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADTSVETGSPIVLEATYSGTPPISVSWMKNEYPLSQSPNCGITTTEKSSILEILESTIEDYAQYACLIENEAGQDICEALVSVLEPPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGELLKDDANLQMSFVHHVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGSFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVAKGDAGQYTCYASNVAGKDSCSAQLGVQEPPRFIKKLDQSRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMS-----FEDSVAILEMHSLSVEDSGDYTCEARNAAGSASSSTSLKVK-------EPPVFRKKPFPVETLKGADVHLECELQGTPPFQVSWHKDKRELRSGKKYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGSDTCVGSVTMKAPPQFVKKLTDISTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWISYSENIATLQFSRAEPANAGKYTCQIKNDAGMQECYATLSVLEPAAIVEKPESIKVTTGDTCTLECTVSGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVVPGDSGVYSFEVQNPVGKDSCKVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGNEISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREPPSFVQKPDPMDVLTGSNVTFTSIVKGSPPFTVSWFKGSTELVPGARCNVSLQDSVGELELFDVDTSQSGEYTCIVSNEAGRASCTTRLFVKAPAIFVKRLNDYSIEKGKPLILEGTFSGTPPISVTWKKNGINVIASQRCNITTTEKSAILEILSSTVEDSGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATCKMHFKNNVATLVFTQVDSSDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNIQTSFLDNIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLILTEGKNPPFFDIPLAPMDAVVGESADLECHVTGTQPIKVTWAKDNREIRSGGNYQISYLENSAHLTIVKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNVEIHPTSNCEIMFKNNALLLQVKRASMADAGLYTCKATNDAGSALCTSSIVIKEPKKPPVFDQHLAPVTASEGDSVQLSCHVQGSEPIRIQWLKAGREVKPSDRCSFSFASGTAMLELKETAKADSGDYVCKASNVAGSDTSKCKVTIKEKPAAAPAAKKAAVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRILIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPALKKGSGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEELEKSERDEKEFEELVAFIQQRLTQTEPVTLIKDIENQTVLKDNDAIFEIDIKINYPEIKLSWYKGTEKLEPSNKYEISIDGDRHTLRVKNCQPKDQGNYRLVCGPHIASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRVLKPQGRVKTEVEHKVHKLTIADVRAEDQGQYTCKHEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLEMKPPDIPDSRVPIPTMPIRAVPPEEIPPAVAPSIPLLLPLPEEKKPPAKRIEVTKKGVKKDTKKVVTKPKEEAPPPP----VAKKPPPPTPMIPAKASEIIDVSSKAEEVKITTITRKKEVHKEKEAVYEREEAVY-EKKVHIEPWEEPYEELETEPYTEPYEEPYYEEPDEDYEEIKVEAKKQVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEIYHEREIIQVQKEVHEELHEKKIPAKVPEKKVPPP-KVVKKPVVEKVEKTTRRMEEEKVQVIKVPEVSKKIVPQKPSRTPVQEEIIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVSVPEVQKKTVTEEKIHVAVSKKIEPPPKVPEPPKKPVPEEVVPVPIPKKVEPPAAKVPEAPKKPVPEEKKPVPIPKKKEPAAPPQVPEAPKKPAPEEKIPVPVTKKKEAPPAKVPEVQKKVVTEEKIAIITQREESPPPAVPEIPKKKVPEEKRPVPRKEE--VPPPKVPVPPKKAVPEAVVPAPIP---KKAPPRAEVSKKTVVEEKRFAAEEKLSVAVPQRVELMRHEE---EEWTYSEEEERVSVSVYREEERDEEE-AEITEYEVLEEPEEYVVEEKMHFISKKVEVEPAKVPE---KKIIPKPKVPAKIEEPPPTKVPEPPKKIVPEKKVPAPAPKK--VPPAKAPEESKRPVPEKRAPAEEVGIEEPPPTKVAERHMKITQEEKVLVAVTKKEAPPRARVPEEPKKVAPEERFPKLKPRREEEPPAKVTEVRKRAVKEEKVSIEVPKREPRPTKEVTVTEEKKWSYTREEETVSEHREEEYEDYEDYEEYKEFEEYEPTEEYDQYDEYAEREVEHYEEHEEY----VTEPKKPVPVKPA-QEPVPAKPKAPPPKVLKKAVPEEKAPLPIQKKLKPLPPKAPEEPKKVVEEKIQISITKREKQQVTEPVAKVPMKPKRVVPEAKIPAPTKEVAVPVRVPGVPKKRELEEVVVFKEEVEAH-EEYIVEEEEEYVHEEEYVHKEEYVHEEEYVHKEEYIHEEEEHLHEEEETIAEEEVVPVAPVKVPVVPKKPVPEEKKPVPVPKKKEAPPAKVPEIPKKPEEKVPVPIPKKEKAPPAKVPEVPKKPVPEEKPPVPVPKKVEPPPAKVPEVPKKPVPEKKVPAPTPKKVEAPPAKVPEVPKKPIPEEKKPTALLKKMEAPPPKAPKKREVVPVPVALPREEEEEEVPFEEVPEEEILPEEEVPSEEEAPPEEVPPEEEEVLPEEEEVLPEEEEVLPEEEEVQPEEEALPEIKPKVPKPAPVPKKTVPEKKVPVPVPKKVEPPPPPKVPEIKKKVPEKKVVVPKKEEAP----------------------------PTKVPEVSKKVEERRIIPPKEEEVPPAEVYEEAEEP--TPEEIPEEPPSIEEEEIVEEEEEEEEVLPPRAPEVVKKAVPEAPTPVPKKAEAPPAKVPKKIPEEKVPVPVQKKEAP-------PAKVPEK-KKIPEKKVPVPKKEAVPPAKGKAVFEEKISVAYQQEELVQERIELELVEAKVEEAFEEEEFHEVQEYFEEEEFHEVEEFIRVEERRFQEEHKVEEVHRVIEFLEAEEVEVYEKPKIPPKKGPEVSEKVIPPKKPPTKVIPRKEPPAKVPEVTKKTVVEEKIRAPEEPKVPAPKAPEVPKKITPEEKVREAVPKKPEVPPPKVPEVPKKIIQEEKLPVVLPEDTEIYMYEASEETVIEEEHVTLPQKARLKVAKVPAPPQTVVTEEKTYVTIRKTRETLALKESETTREAFPELKSYKAVPEIPEPPSPEDLEIIEDVLPEKRPPASKRRKTQLPTAPEAPREMPPEMNTFEEISVEPEMLPTQ-------------------------VLDTYQEATVEKKTLRISRKKPELPSDEEVPEAPREVVAKKKVLPPQVPEVVPVKVPGAPKEVVSERKSLEEPPKKPAVRPVTVPEEPKEVIPEKKVSLVPPKKPAAPPVTVPEAPEEVFSEDEETLAPPQEPEAPPAKVPEAPKEVVPEKKVSVVPPKKPEAPPAKVPEAPKEAAPEKKVPVAPKKKPEAPPVKVPEAPKKVVPEKKLPVAAPKKPEAPAAEVPEVPKTAVPQKKIPEAIPPKPESPPLEVPEVPPKEVTPEKKVPAAPPTKPEIPPPKVPEAPQAAVVEEKTPEALPKKAEAAPVPVPQVQETVPEKTRPVGPPKKPEATTVPVPKVQKTIPEKTRPEAPPKRPEARTVP-----ETVPEKTRPMAPPKKPEATTLPVPEVQETVPEKTRPVGPPKKPEATTVPVPEVQETIPEKTRP---PKKPEATPVPVPEVQETVPEKTRPVGPPKKPEATTVSVPEVQETIPEKTRPAAPPKKPEATAVPETIPEKTRPEAPPKRPEATTVPVPEADQAVVPEKKVPRVPPKKVEAPPITVPEEPKEVIPEKKVSLVPPKKPAAPPVTVPEAPEEVFSEDEETLAPPQEPEAPPAKVPEAPKEVVPEKKVSVVPPKKPEAPPAKVPEAPKEAAPEKKVPVAPKKKPEAPPVKVPEAPKKVVPEKKLPVAAPKKPEAPAAEVPEVPKAAVPQKKIPEAIPPKPESPPPEVYEEPEEEIVPEEPPEEAVEEPVPAPPPKVTEPPKKPVPEKKAPPAVVKKPEPPPAKVPEVPKEAPPEKKVP---PKKPEAPPAKVPEVPKEVVTEKKVAVPKKPEVPPAKVPEVPKK------PVIEEKPAIPVVEKVASPPAEVYEEPEEVTAEE------EEPAPAVEEEEYEAPPPPAPVPEEPKKVVPEKKFPVIKKPEAPPPKVPEVPKKAVPVKKVPVVKKPEPPEAEVPEVPKKLVPVKKEPVPVTKKTEVLPEKVPEAPKKITPEKKESVPVPEEPEAPPASVEETPEETIYEEKATITIGRKETPPVEEREIEKFIQPEEPELEPEPEEIPVQEPEPEKKVIEKPKLKPRPPARPPSPPKEDVKEKMFQLKAVSKKKVPEKPEVVEKVEPAPLKVPTAEKKVRKLLPEPKPQPKEEVVLKSVLRKKPEEEEPKVEPKKVEKAKKPEEPQPPPKAVEVEAPPEPTPKERKVPEPAKVPEIKPAIPLPGPEPKPKPEPEVKTMKAPPIEPAPTPIAAPVTAPVVGKKAEAK-PKDEAAKPKGPIKGVAKKTPSPIEAERKKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIVLTEAESVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEIIREWLVKPIRDQHVKPKGTAVFTCDIAKDTPNIKWFKGYDEIPLEPNDKTEILKEGNHLFLKVKNAMPEDIDEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEEDIPGEWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQACNAITTAILTVKEIELDFAVPLKDVTVPEKRQARFECVLTREANVIWSKGPDIIKASDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSAQLFVTGIRLKFISPLEDQTVKEGQ--TATFVCELSHEKMHVVWFKNDVKLHTTRTVLMSSEGKTYKLEIRETTLDDISQIKAQVKNLSSTANLKVLEADPYFTVKLHDKTGVEKDEIILKCEVSKDVPVKWFKDGEEIVPSPKHSVKTDGLRRILKIKKAELKDKGEYVCDCGTDTTKANVTVEARLIKVEKPLYGVEVFVGETARFEIELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKHVLVLYNCQLDMTGEISFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTR--HSLVIKSAAFEDEAKYMFEAEDKRTSGKLIIEGIRLKFLTPLKDVTAKERENAVFTVELSHDNIPVSWFKNDQRLHTSKRVSMHDEGKTHSITFKDLSIDDTSQIRVEAMGISSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNVVIKADGKKRMLILKKALKSDIGQYTCDCGTDQTSGKLDIEDREIKLVRPLYSVEVMETETARFETEISEDDIHANWKLKGEALLQTPECEIKEEGKIHVLILHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPNDKVVTRSEGRVHTLTLRDVKLEDAGEVQLTAKDFKTQANLFVKEPPVEFTKPLEDQTVEEEATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLIIHGCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVKEKETARFECEISKENEKVQWFKDGAEIKKGKKYDIISKGAVRILVINKCLLNDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLANLEVSEGDTIKLVCEVSKPGAEVIWYKGDEEIIETGRFEILTDGRKRILIIQNAQLEDAGSYNCRLPSSRTDSKVKVHELAAEFISKPQNLEILEGEKAEFVCTISKESFEVQWKRDDQTLESGDKYDIIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIIVPLKDTKVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDARLDDQANFNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVAFDNRISYRIDKYKHSLIIKDCGFPDEGEYVVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLEDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVIFLAELNKDKVEVQWLRNNMIVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDAGQPLTMVVPYDAYPKAEAEWFKENEPLSTKTVDTTAEQTSFRISEAKKDDKGRYKIVLQNKHGKAEGFINLQVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLVTDRADSCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDSPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLNASEQTQSSVQLTWEPPLKDGGSPILGYIIERREEGKDNWIRCNMKPVPELTYKVTGLQKGNKYLYRVSAENAAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPIKILVPSTGYPRPKATWTFGDQVLEEGDRVKMKTISAYAELVISPSERTDKGIYTLTLENPVKSISGEINVNVIAPPSAPKELKFSDITKDSVHLTWEPPDDDGGSPLTGYVVEKRDMSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYTDEPVNMSAPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVEKCPRGSDKWVACGEPVPDTKMEVTGLEEGKWYAYRVKALNRQGASKPSKPTEEIQAVDTQEAPEIFLDVKLLAGITVKAGTKIELPATVTGKPEPKITWTKADTLLKPD-QRITIENVPKKSTVTITDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERKATDSDVWHKLSSTVKDTNFKATKLTPNKEYIFRVAAENMYGVGEPVQAAPIIAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSRSTEPILIKDPIDPPWPPGKPTVKDIGKTSLVLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEG-VPTTEHLLTGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIGDSVLAKDTFTTPGPPYALTVVDVTKRHVDLKWEPPKNDGGRPIQRYIIEKKEKLGTRWVKAGKTSGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGIVPDKEYVLRVRAVNAVGVSEPSEISENVVAKDPDCKPTIDLETHDIVVIEGEKLNIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVHADAGVYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGSPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKIGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAKAMTITWKPPLYDGGSKIMGYIIEKITKGEDRWKRCNEHLVPVLTYTAKGLEEGKEYQFRVRAENAAGIGEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDATISGSPYPTITWIKDENVIVPEEIKKRAAPPVRRKKGEAEEEEPFSLPLTERLSINNSKQGESQLRIRDSLRPDHGQYMIKVENDHGVAKAPCSVSVLDTPGPPINFVFEDIRKDSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSDWIVITSTLRNCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLLAKDPFEPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKTLLSSLKTKVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTARDPISPPGPPVPRVADTSSTTIELEWEPPAFNGGGEIMGYFVDKQLVGTNEWSRCTEKMIKVRQFTVKEIREGADYKLRVSAVNAAGEGPPGETEPVTVAEPQEPPTVELDVSVKGGIQIMAGKTLRIPAEVTGRPVPTKVWTIEEGE--LDKERVIIENVGTKSELIIKNALRKDHGRYVITATNSCGSKFAAVRVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPADDGGSDITGFIIERKDAKMHTWRQPIETERSKCDITGLIEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSDGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNDVGESEPSLPLNVVIQDDEVPPTIKLRLAVRGDTIKVKAGEPVNIPADVTGLPMPKIEWSKNEKVIDKPTDTLNITKEEVSRSEAKTELSIPKAAREDKGTYTITASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYIIDKRDASRKKSEWEEVTNTAVERRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLERTKGSMLVSWTPPLDNGGSPITGYWLEKREEGGTYWSRVSRAPITKVGLKGVEFNVPRLIEGVKYQFRAMAINAAGIGPPSEPSDPAVAGDPIYPPGPPSCPEVKDKTKSSISLAWKPPAKDGGSPIKGYIVEMQEEGTTDWKPVNEPDKLLTACECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEVPEVFIDIGAQDCLVCKAGSQVKIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECTRAHSGKYSITAKNKAGQKTANCRVKVMDAPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKKTIDGKAWTKVNPNCGSTTFVVPDLISEQQYFFRVRAENRFGIGPPAETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGKKKEAWRQCNRRDVEELEFTVEDLIEGGEYEFRVKAVNEAGVSKPSATVGPVIVKDQTCPPAIELKEFMEVEEGTDVNIVAKIKGVPFPTLTWFKAPPKKPDSKEPVVYDTHVNKQVVDDTCTLVIPQSRRSDTGLYSITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESISADQMTLSWLPPKDDGGSKITNYVIEKREANRKTWVRVSSEPKECMYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPVTARDPVAPPGPPFPKVTDWTKSSVDLEWSPPLKDGGSKITGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNVAGVGEPGEVTDVIEMKDRIVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWSMNERALPQEAAIETTAISSSMVIKNCQRSHQGVYSLLAKNEGGERKKTIIVDVLDVPGPVGIPFLSDNLTNDSCKLTWFSPEDDGGSPITNYVIQKREADRRAWTPVTYTVTRQNATVQGLIQGKSYFFRIAAENSIGMGPFVETPNALVIRDPITVPERPEDLEVKEVTKNTVSLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLDLDFRDKLTVRVGESFALTGRYSGKPKPKIDWFKDEADVLEDDRTHIKTTPTTLALEKTKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVIFDEVTKEYMVISWKPPLDDGGSEITNYIIEKKELGKDIWMPVTSASAKTTCKVPKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPEQPVVTEVTKDSALVTWNKPNDGGKPITNYILEKRETMSKRWVRVTKEPIHPYTKYRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFARDPIAKPSPPINPEAIDTTCNSVELTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQSYKFRVLAVNEAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIRVGDTLRLSAIIKGVPFPKVTWKKEDREAPTKAQIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGTKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVVTNYVVERKDVATAQWSPLSTTSKKKSHMAKHLTEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGDKDWIKFKTVKNLDCVVTGLQQGKTYRFRVKAENIIGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGTEIKTDDHYTVETDSFSSVLTIKNCLRKDTGEYQLTVSNAAGTKTVAVHLTVLDVPGPPTGPINILDVTPEYMTISWQPPKDDGGSPVINYIVEKQDTRKGTWGVVSAGSSKLKLKVPHLQKGCEYVFRVKAENKMGVGPPLDSIPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYVERREITGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSNPSPSSDPIKACRPIKPPGPPINPKLKDKSKESADLVWTKPLSDGGSPILGYVVEYQKPGTAQWDRINKDELIRQCAFRVPGLIEGNEYRFRIRAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWSKEGKVLVKDKRVDLIHDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVSNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLVKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSADWERVHKGSIKETHYMVDKCVENQIYEFRVQTKNEGGESDWVRTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTSAESSKFSLTKAKRSDGGKYVITATNPAGSFVAYATVNVLDKPGPVRNLKITDVSSDRCTIRWDPPEDDGGCEIQNYILEKCESKRMVWSTYSANVLTPSATVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDRPGRPDPPEVTKVSKEEMTVVWNAPEYDGGKSITGYYLEKKEKHAVRWVPVNKSAIPERRLKVQNLLPGHEYQFRVKAENEVGIGEPSLPSRPVVAKDPIEPPGPPTNFKVVDTTKSSITLAWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLIRMEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVVVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVKVLDTPGPVADLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREAERKTWSTVTPEVKKTSFNVTNLVPGNEYFFRVTAVNEYGPGVPTDIPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYIISYREEDQPADRWTEYSVVKDLSLIVTGLKEGKKYKFRVAARNAVGVSMPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRVEAHVYGKPNPICKWKKGDDEVVTSSHLAIHKADGSSVLIIKDVTRKDSGYYSLTAENSSGSDTQKIKVTVMDAPGPPQPPFDISEIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMLAKFPFDVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPITGYLIERKERNSLLWVKANDTIVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVVDVTKNSASLIWARPKHDGGSRIIGYFVEACKLPGDKWVRCNTTPHQIPQEEYTATGLEENAQYQFRAIAKTAVNISQPSEPSDPVTILAENVPPRIELSVEMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDTTPIKQAEGIKMAMKRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYADRAMLSWEPPLEDGGSEITNYIIDKRETSRPNWAQVSATVPITSCTVEKLIEGHEYQFRICAENKYGVGDPILTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKAPADDGGSPITGYLVEKRETQAVNWTKVNRKPVIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAVYAQDPLYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDHWVRCNLPEKLQKTRFEVTGLMENTEYQFRVYAVNKIGYSDPSDVPDKHCPKDILIPPEGELDAELRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRERIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEVSKDSAYVTWDPPIIDGGSPIINYVVEKRDAERKSWSTVTTECSKTSFRVSNLEEGKSYFFRVFAENEYGIGDPGETRDAVKASETPGPVVDLKALAITKSSCTIGWKKPRSDGGSRITGYVVDFLTEENKWQRVMKSLSLQYSTKDLKEGKEYTFRVSAENENGEGTPSEIVVVAKDDVVAPDLDLKDLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESTAVNTTLVVYDCQKSDAGKYTITLKNVAGTKEGTLSIKVVGKPGIPTGPIKFDEVTAEAMTLKWGPPKDDGGSEITNYVLEKRDSVNNKWVTCASAVQKTTFRVTRLHEGIEYTFRVSAENKYGVGEGLKSEPIVAKHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHIEFKERNSLLWKRANKTPIRMKDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVISVTRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPDCAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTGTIICKDEYEAPTIVLDPTIKDGLTVKAGDSIVLSAISILGKPLPKSSWSRAGKDIRPSDIAQITSTPTSSMLTVKYATRKDAGEYTITATNPFGTKEEHVKVSVLDVPGPPGPIEISNVSAEKATLTWTPPLEDGGSPIKAYVLEKRETSRLLWTVVSEDIQACRHVVTKLIQGNEYLFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPGKPEISNVTKNTATVSWKRPTDDGGSEITGYHVERREKKGLRWVRATKTPVSDLRCKVTGLQEGNTYEFRVSAENRAGIGPPSDASNPVLMKDVAYPPGPPSNAHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDDAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPNVEIVEKEVAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDN--INLKHRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTVTTKCHKCTYKVTGLTEGCEYFFRVMAENEYGVGEPTETTEPVRASEAPLPPDSLNIMDITKNTVSLAWPKPRHDGGSKITGYVIEAQRKGSDQWTHISTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIARAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNVENTATSTILNINECVRSDSGPYPLTAKNTVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWEPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGVEYQFRVRAQNRYGVGPGITSASVVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHIERKERNGILWQTVSKALVPGNIFKSTGLTDGIAYEFRVIAENMAGKSKPSKPSEPMFALDPIDPPGKPVPLNITRHTVALKWAKPEYTGGFKITSYVVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDLEAPRIMVDVRFKDTITLKAGEAFKLEADVSGRPPPTMEWTKDGKELEG-TGKLEIKIADFSTHLINKDSSRTDSGAYILTATNPGGFAKHIFNVKVLDRPGPPEGPLAVSDVTSEKCVLSWLPPLDDGGAKIDHYIVQKRETSRLAWTNVATEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE-PVLAVDPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWVKCNKKALTDLRFKVSGLTEGHEYEFRIMAENAAGISAPSATSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQVVTPPAGLKATSYTITSLIENQEYKIRIYAMNSEGLGEPALVPGTPKAEERMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWAREHGESLDKASIESTSSYTLLVVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQNLKIKEVTKTSVTLTWEPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLTDVTRNSVSLSWEKPEHDGGSRILGYIVEMQSKGSDRWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKIDVPFIGRPPPAVTWHKDDIPLKQTTRVNAESTENNSLLTIKEACREDVGHYTVKLTNSAGEATETLNVIVLDKPGPPTGPVKMDEVTADSVTLSWEPPKYDGGSSINNYIVEKRDTSTTAWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSE-PVVAQYPFKVPGPPGTPFVTLASKDSMEVQWHEPVSDGGSKVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGIEYEFRVSAENIVGIGKPSKPSECYAAHDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPDGRWMKASFTNIIDTQFEVTGLLEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVEPPRISMDPKYRDTVVVQAGESFKIDADIYGKPIPTTQWVKGDQELSSTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGEKSVTINVKVLDRPGPPEGPVAISGVTAEKCTLAWKPPLQDGGSDITNYIVERRETSRLVWTLVDANVQTLSCKVLKLLEGNEYIFRIMAVNKYGVGEPLESESLIAKNPFVVPDAPKAPEVTAVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLLENHNYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVMDVTRSSVFLSWTKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNLEVEKLLEKHEYNFRICAINKAGVGEHADVPGPVMVEEKLEAPDIDLDLELRKVINIRAGGSLRLFVPIKGRPTPEVKWGKVDGDIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPARTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKNTDKWSECARVKSLDAVITNLTQGEEYLFRVIAVNEKGRSDPRSLAVPIIAKDLVIEPDVRPAFSSYSVQVGQDLKIEVPISGRPKPSISWTKDGMPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVSNVVGQKTAAIEIITLDKPDPPKGPVKFDEISAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESEPVVAQYPYKEPGPPGTPFVTAISKESMVVQWHEPINNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKALNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEAIIVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPEGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTAEKCTLAWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNKYIFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHVVDTTKNSITLAWSKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEIAKLIEHQEYKIRVCALNKVGLGEAASVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSKEEGEFTDKVQIEKGINFTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSVLLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCNKTSFRVENLTEGAIYYFRVMAENEFGVGVPTETSDAVKASEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRILGYVVEMQPKGTEKWSVVAESKVCNAVVSGLSSGQEYQFRVKAYNEKGKSDPRVLGIPVIAKDLTIQPSFKLPFNTYSVQAGEDLKIEIPVIGRPRPKISWVKDGEPLKQTTRVNVEETATSTILHIKESSKDDFGKYSVTATNSAGTATENLSVIVLEKPGPPVGPVKFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTNWQMVSATVARTTIKISKLKTGTEYQFRIFAENRYGKSTPLDSKPVVVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGSKVTGYHLEQKEKNSILWVKLNKIPIQDTKFKTTGLDEGLEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIVITRNSVTLKWKKPVYDGGSKITGYIVEKKDLPDGRWMKASFTNVVETEFTVTGLVEDQRYEFRVIARNAADNFSEPSESSGAITARDEIDAPNASLDPKYRDVIIVHAGETFVLEADIRGKPIPDIIWSKDGNELEETAARMEIKSTLQKTTLIVKDCIRTDGGQYTLKLSNVGGTKTIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGASISHYIIEKRETSRLSWTQVSNEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEALESEPVIACNPYKRPGPPSTPEASAITKDSMVLTWTRPVDDGGAEIEGYILEKRDKEGIRWTKCNKKTLTDLRFRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWNKPIYDGGAPVRGYVIELKKAAADEWTTCTPPSGLQGKQFTVTKLKENTEYNFRICAFNTEGVGEPATIPGSVVAQERMEAPEIELDADLRKVVTLRASATLRLFVTIKGRPEPEVKWEKAEGILTERAQIEVTSSYTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKNTFKIENLQEGCSYYFRVLASNEYGIGLPAETAEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSACTQVKTLETTISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIAKDIEIKPSVELPFNTFNVKANDQLKIDIPFKGRPQATVAWKKDGQVLRETTRVNVASSKTVTTLSIKEASREDVGTYELCVSNTAGSITVPITVIVLDRPGPPGPIRIDEVSCDNVSISWNPPEYDGGCQISNYIVEKRETTSTTWQVVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMVVSWQVPVNDGGSQVIGYHLEYKERSSILWSKANKVLIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKACEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPRYDGGAKITGYIVERRELPDGRWLKCNFTNVQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPITVKDDVEAPRIMMDVKFRDVIIVKAGEVLKINADIAGRPLPVISWAKDGVEIEERAKTEIVSTDYTTTLTVKDCVRRDTGQYVLTLKNVAGTRTMAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSRLAWTICEAELRTTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESM-AVKALDPFTTPSPPTSLEITSVTKDSMTLCWSRPETDGGSDISGYIIERREKNSLRWMRVNKKPVYDLRVKSTGLREGCEYEYRVFAENAAGLSLPSETSPLVRAEDPVFLPSPPSKPKIVDSGKTTITIGWVKPLFDGGAPITGYTVEYKKSEETDWKVAIQSFRGTEYTMSGLTTGDEYVFRVRSLNKMGASDPSDSSDPQVAKEREEEPVFDVDSEMRKTLIVKAGSSFTMTVPFRGRPIPNVSWSKPDTDLRTRAYIDSTDSRTLLTIENANRNDSGKYTLTIQNVLSAASMTFVVKVLDSPGPPANITVREVTKETAMLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGVPAETKEGVKITEKPSPPEKLGVTSVSKDSVSLSWLKPEHDGGSRIIHYVVEALEKGQKTWVKCAVVKTTHHVVSGLRESHEYFFRVFAENQAGLSDPRELLLPVLIKDQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTTDAGRYEITAANSSGTTKTFINIIVLDRPGPPTGPVAISDITEESVTLKWEPPKYDGGSHVTNYIVLKRETSTAVWSEVSATVARTMIKVMKLTTGEEYQFRIKAENRFGISDHIDSVCVVVKLPYTTPGPPSTPWVSNVTRESITVGWHEPVSNGGSAVTGYHLEMKDRNSILWQKANKMIIRTTHFKVTTISAGLIYEFRVYAENAAGIGKPSHPSEPVLAIDACEPPRNVRITDISKNSVNLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVIETQFTVSGLTQNSQYEFRVFARNAVGSVSNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPEPTIEWYKDDKELQTNALVCVENSTDLASILIKDANRLNSGSYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVAENLEECIVTTTKIIKGNEYVFRVRAVNKYGIGEPLESEPVVAKNAFVTPGPPSIPEVTKITKNSMTVVWDRPTVDGGSEINGYFLERRDKKSLAWLKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGVGPFSEPSDFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSDVTGYVVEMKQGDEEEWTIVSTRGEVRTTEYVVSNLKPGVNYYFQVSAVNCAGQGEPITMTEPAQAKDVLEEPEIDLDVALRTSVIAKAGEDVQLLIPFKGRPPPTVTWRKDEKNLGSDTRYSIQNTDSSSLLVIPQVTRNDTGKYILTIENGVGQPKSSTVSVKVLDTPAACQKLQVKHVSLGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSGTSFKVTDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVVLSWTKPDFDGGSIITDYLVERKGKGEQAWSHAGISKTCEIEIGQLKEQSVLEFRVSARNEKGQSDPVTIGPLTVKELVITPEVDLSEIPGAQISVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEYVRFSKTENKITLSIKNSKKEHGGKYTVILDNAVCRNSFPITIITLGPPSKPKGPIRFDEIKADSAIMSWDIPEDDGGGEITCYSIEKREASQTNWKMVCSSVARTTFKVSNLVKDSEYQFRVRAENRYGVSEPLASNIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQRVNTSPISGREYRATGLIEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVAYSIEKRQGSDRWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGLIMTRDENVPPTVEFGPEYFDGLVIKSGDSLRIKALVQGRPVPRVTWFKDGVEIERRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNVSGSTKAEVTVKVQDTPGKVVGPIRFTNITGEKMTLWWEAPLNDGCAPVTHYIIEKRETSRLAWALIEDNCEALSYTAIKLITGNEYQFRISAVNKFGVGRPLESDPVVAQIQYTIPDAPGVPEPSNVTGNSITLTWTRPESDGGSEIQHYILERREKKSTRWVKVISKRPISETRFKVTGLVEGNEYEFHVMAENAAGIGPASGISRLIKCREPVNPPSAPSVVKVTDTSKTTVSLEWARPVFDGGMEIIGYIIEMCKADLGDWHKVNTEPCVKTRYTVTDLQAGEEYKFRVSAVNGAGKGDSCEVTGTIKAVDRLSAPELDIDANFKQTHIVRAGVSIRLFIAYQGRPTPTAVWSKPDSNLSIRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGKKSITFTVKVLDSPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVIEKREASRRSWQVVSEKCTRQILKVSELTEGVPYYFRVSAENEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITSYLLEMRQKGSDFWVEAGHTKQLTFTVERLVENTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSTFTIDVPISGRPAPKVTWKLEEMRLKETDRMSIATTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFTITVVVIGRPGPVTGPIEVSSVSAESCVLSWTEPKDDGGTEITNYIVEKRESGTTAWQLINSSVKRTQIKVTHLTKYKEYCFRVSSENRFGVSKPLESVPIVAEHPFVPPSAPTRPEVYYVSANAMSIRWEEPYHDGGSKIVGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDPPGRPEVTDVTRSTVSLIWSAPVYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLQGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKISLQYTGKRATAVIKYCDRSDSGKYTLTVKNASGTKSVSVMVKVLDSPGPCGKLTVSRVTEEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECLTASYVVTRLIKNNEYTFRVRAVNKYGLGVPVESEPIVARNSFTIPSQPGIPEEVGAGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKRSISLAWTKPMYDGGTDIIGYVLEMQEKDTDQWCRVHTNATIRNNEFTVPDLKMGQKYSFRVAAVNAKGMSDYSETTAEIEPVERLEIPDLELADDLKKTVIVRAGASLRLMVSVSGRPSPVITWSKKGIDLANRAIIDNTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVSVKEVSRDSVTITWEIPTIDGGAPVNNYIIEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPTKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVISLNEGEQYLFRVRAQNEKGVSEPREIVTPVTVQDLRVLPTIDLSTMPQKTIHVPAGRPIELVIPITGRPPPTASWFFAGSKLRESERVTVETHTKVTKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSVTISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRPTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSISIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLIEGLEYEHRVTAINARGTGKPSRPSKPTVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQREWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGVFVRQGGVIRLTIPIKGKPFPVCKWTKEGQDISKRAMIATSETHTELVIKEADRNDSGTYDLVLENKCGKKTVYIKVKVIGSPNTPEGPLEYDDIQARSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVIPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDRQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSVKTKLTSG-EAPGVRKEMADVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSR-KYKMSSDGRTHTLTVMTDEQEDEGVYTCVATNEVGEVESSSKLLLQAAPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSEKITIENTEHYTHLVMKNVQ--RKTHAGKYKVQLSNAFGTVDATLDVEIQDKPDKPTGPIVIEALLKNSVVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISEPLEVASIVIIKSPFEKPGVPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLERREKKQNKWIAVTTEEIRETVFSVQNLIEGLEYEFRVKCENLGGESEWSEISEPVTPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFSNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKVTNYIVEKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTVTKEDKTR-----------------------AMNYDDEVDETREVTTTKASHSKTKELYEKYMIAEDLGRGEFGIVHRCVETSSKRTFMAKFVKVKG-TDQVLVKKEISILNIARHRNILYLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVRQVCEALEFLHSQNIGHFDIRPENIIYQTRKNSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQMIENIMNAEYTFDEEAFKEISLEAMDFVDRLLVKERKSRMTASEALQHPWLKQRIDRVSTKVIRTLKHRRYYHTLIKKDLNMVVSAARISCGGAIRSQRGVSVAKVKVASIEIGPVSGQIMHAIGEEGGYVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVATMYVKDITKFDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRR-TKKVKRRTDAMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPRVTWYKSGQKIKPGDDEKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKHGEDSCKAKLTVTLHPPPTETTLRPMFKRLLANAECHEGQSVCFEIRVSGIPAPTLKWEKDGQPLSLGPHIEIVHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYVKQEFQSKEERERHVQKQIDKTLRMAEILSGTETVPLTPVAQEALREAAILYKPAVSTKTVKGEYRLQTEEKKEERKLRMPYEVPEPRRFKQATVEEDQRIKQFVPMSDMKWYKKIRDQYEMPGKLDRVVQKRPKRIRLSRWEQFYVMPLPRITDQYRPKWRIPKLTQDDLEMVRPARRRTPSPDYDLYYYRRRRRSLGDMSDEELLLPIDDYLAMKRTEEERLRLEEELELGFSASPPSRSPPRFELSSLRYSSPPAHVKVEDRRRDFRYSTYHVPTKEETSTSYAELRERHAQASYRQPKLRQRIMAEKEEEELLRPVTTTQRLSEYKSELDYMSKEEKSKKKSKRQRQVTEITEIEEEYEISRRAQRESSSSVSRLLRRRRSLSPTYIELMRPVSELIRSHPRPAEEYEDDAERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCQTEDGGTYRAVCTNYKGEASDYATLDVTGGAYTTYASQRRDEEVPKSVFPELTKTEAYAVSSFKRTSELEAASSVREVKSQMTETRESLSTYEHYASAEMKSATSEEKSLEEKATVRKIKTTLAARILTKPRSITVHEGESARFSCDTDGEPVPTVTWLREGQVVSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSDGKQEAQFTLTVQKARVIEKAVTSPPRVKSPEPRVKSPETVKSPKRVKSPEPVTSHPKAVSPTETKPT--EKGQHLPVSAPPKITQSLKAEASKDIAKLTCAVESSALCAKEVAWYKDGKKLKENGHFQFHYSADGTYELKIHNLSESDCGEYVCEVSGEGGTSKTSFQFTGQSFKSIHEQVSSISETTKSVQKTAESPEAK----------------------------------------------------KQEPIAPESISSKPVIVTGLRDTTVSSDSVAKFTIKVTGEPQPTITWTKDGKAIAQGSKYKLSSNKEEFILEILKTETSDGGLYACTVTNSAGSVSSSCKLTIKAVKDTEAQKVSTQKTSEVTSQKKASAQEEISQKALTSEEIKMSEVKSHETLAIKEEASKVLIAEEVKRSAAASLEKSIVHEEVTKTSQASEEVKTHAEIKTLSTQMNITKGQRATLKANIAGATDVKWVLNGTELPNSEEYRYGVSGSDQTLTIKQASHREEGILSCIGK--TSQGVVKCQFDLTLSEELSDAPSFITQPRSQNINEGQNVLFSCEVSGEPSPEIEWFKNNLPISISSNISVSRSRNVYTLEIRNAAVSDSGKYTIKAKNFHGQCSATASLTVLPLVEEPPREVVLKTSSDVSLHGSVSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGKSSMTQLESSTSRMLKAGGRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEITWSCGGRKIQNQEQQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNINIRSM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WZ42-1", "uniprot_id": "TITIN_HUMAN", "id": "Q8WZ42-1", "name": "Titin", "aln": "MTTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGYVASSSEAEMRETTLTTSTQIRTEERWEGRYGVQEQVTISGAAGAAASVSASASYAAEAVATGAKEVKQDADKSAAVATVVAAVDMARVREPVISAVEQTAQRTTTTAVHIQPAQEQVRKEAEKTAVTKVVVAADKAKEQELKSRTKEVITTKQEQMHVTHEQIRKETEKTFVPKVVISAAKAKEQETRISEEITKKQKQ--VTQEAIRQETEITAASMVVVATAKSTKLETVPGAQEETTTQQDQMHLSYEKIMKETRKTVVPKVIVATPKVKEQDLVSRGREGITTKREQVQITQEKMRKEAEKTALSTIAVATAKAKEQETILRTRETMATRQEQIQVTHGKVDVGKKAEAVATVVAAVDQARVREPREPGHLEESYAQQTTLEYGYKERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADTP--DTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMS----PARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDSEQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQELQSILEQDKLTPESTREFLCINGSIHFQPLKEPSPNLQLQIVQSQKTFSKEGILMPEEPETQAVLSDTEKIFPSAMSIEQINSLTVEPLKTLLAEPEGNYPQSSIEPPMHSYLTSVAEEVLSPKEKTVSDTNREQRVTLQKQEAQSALILSQSLAEGHVESLQSPDVMISQVNYEPLVPSEHSCTEGGKILIESANPLENAGQDSAVRIEEGKSLRFPLALEEKQVLLKEEHSDNVVMPPDQIIESKREPVAIKKVQEVQGRDLLSKESLLSGIPEEQRLNLKIQICRALQAAVASEQPGLFSEWLRNIEKVEVEAVNITQEPRHIMCMYLVTSAKSVTEEVTIIIEDVDPQMANLKMELRDALCAIIYEEIDILTAEGPRIQQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMS-----FVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK-------EPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREE----IVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKK-EPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYD-YKEFEEYEPTEEYDQYEEYEEREYERYEEHEEY----ITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMK---------------------------PKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEE-----EEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEE------------------VLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPE----EEEFVPEEEVLPEVKPKVPVPAP--VPEIKKKVTEKKVVIPKKEEAP----------------------------PAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVA---------PPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAP-------PAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPK-GPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEP-EEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKK------PVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPP--AVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEK---------VIEKPKLK-------------------------------------------------PRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEK-VELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRP-------EEEEPKVEPKKLEKVKKPAVPE--------------------------------------------------------------------PPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERRQARFECVLTREANVIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGE--TATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTK--HSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQD-KRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEG-VPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGE--LDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPVTVKDQTCPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDN--INLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEG-TAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE-PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSE-PTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESV-AIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSG-EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSR-KYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQ--RKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTR-----------------------AMNYDEEVDETREVSMTKASHSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVKG-TDQVLVKKEISILNIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKDLNMVVSAARISCGGAIRSQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLRMAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLRMPYDVPEPRKYKQTTIEEDQRIKQFVPMSDMKWYKKIRDQYEMPGKLDRVVQKRPKRIRLSRWEQFYVMPLPRITDQYRPKWRIPKLSQDDLEIVRPARRRTPSPDYDFYYRPRRR-SLGDISDEELLLPIDDYLAMKRTEEERLRLEEELELGFSASPPSRSPPHFELSSLRYSSPQAHVKVEETRKDFRYSTYHIPTKAEASTSYAELRERHAQAAYRQPKQRQRIMAEREDEELLRPVTTTQHLSEYKSELDFMSKEEKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPE--PSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTR----------------------------------------------------KTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISK--TKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ-GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D1YSG0-1", "uniprot_id": "D1YSG0_DROME", "id": "D1YSG0-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVAEDFAPSFVKKPQLHQED-DGNRLIFECQLLSSPKPDIEWFRSDNKVVEDVRTKFKIQP----------------------------------------------------------------------------------------VGENKYTVVLELDDVVETDAGLYKVKAKNKSGEVSASINLNFTPADEPKEKQIDG----------------------------------------------------------------------------------FAPTFAKKPAIRQEEDGKRLLFECRVNADPIPAIIWFHNGAAVKESERHKITVDK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVHSYFATLEILNVTVEDAGKYKVNAKNELGESNATISLNFDSDEAPVPESAEG---------------------------------------------------------------------------------IKPTFTERPVIRQSEDGGNVTFECRCVGDPTPTVTWSHGETELNESNRYKMSLT-------------------------------------------------------------------------------------------MDQKLYHIACLEISSVVSSDQGEYRAQAKN----------------------------------------KHGSGVATINLNFESGSKKIPDG-----------------------------------------------KSPRFPKKP---TIRQEEDLLIMECVLEAHPVPDIVWYCSEKEICNNQRTKMTRKAITKDSYILTLEIQNPTKEDGGNYRCNAINMYGESNANIALNFQGASDANGFAPSFIEKPRIIPNESGTLITMKCKCKAKPEPTVTWYRGQDLVEKSKKIKINTTVIAEDTYELTLEIKDP-----------------------------------------------------------------------------------------GATDGGTYRCNVKNEYGESNANLNLNIEAEPEPEGEG-----------------------------------------------------------------------------------------PTFIEKPRIVSENNGKLVIMECKVKADPKPDVIWFRNGEVIKESNKIKTFIEQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGDQYYIKLELLDPQLEDSGLYKCNIKNTLGELNANLTLNIEIVPVIKDKPKIIKIIKKRTVVIECTVASKFEPKCTWYKETSTVKESKRHVYQVEQTKEGEFAVKLEIN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVEESDKGAYKLVASNEKGE----------------------------------------------AVSQIVNLVDIPEEE---------------------------------------------RKPCKPEISRKLADQKVAESKTFELLVSLSQTDRKCKVEWYKGSTVIRETKDITTTFDGTTARLTFSSARTEHTSNYKVIVTNEVGKDESSCKITVEKVAKKK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEKPKEKEKTKNEKEVEQKEMEEDKNESGQSVAQTEGRINIEQIS---------------------------------------------------------------------------------------------------------------------------EGDPKEELTVKEEILDKRDTQEVKESSVELQDSAGHEVPEPKKATSDSKLDQSNQKNLDKKHKTDQSESKTNKNVSLAEPIKSNKQES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEQQATEQIGLKKVDRKASIVSVKEEISSDVRRKSTIKAKEEITVDDKKASSRRSSLAVEESNTESRRSSIIDKKPLEQVDNKPIDANKNPQPLKEEIPRLKPAEKRRTSKVIEEP--------------------------------------------------------------KPDEGLPKLRKASIAQVKEEAKPAAPKLKAKAKAKPKYEELPEIPDYERPQLEKYEKSDFTPSDFARDLEIPNKMEKPIIDSGKKEPAVLAQKNGIPKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDIIEQYADEPKGLKVGKGKLPDEGDGRDGAVLKPVIIEPEKEILDLGNKKNNQHADKPTVLDIIKQRRRSSIRNLMTKEP-----------------------------------------------------------------------------------------------IQNESFLGVVLKPVIKDTREQAAPQQAIQLTKANATEQFSPTKAVKAQVADLKK---------------------------------------------------------------------------------------------------------------------PETLATLEDNYERPVLEKYDPFSIDKTK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEKSTPSIITPDIRGPEVKLPVQETKEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQKVPKMQPPAPGDPP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KIEVIREKRPSLAPEPPSRRGSLIPPAD-----------------------TGRRPSLIINDEKKLRPGE---------------------------------------------------VMDTRLLRPGEVGEGQRRRPSIDVRRPSVQDLEDLINKP---------------STPLRDVGDGGPPSIVDVQESYSVVEDSTAYLTVGVE--------------------------------------------------------------------------------------------GSPAPTFKFYKGVSEILEGGRFKFLTDGQTNTITLCMRKCKPNDESKYKIVVSN------------------------IHGEDSAEMQLYVSD--------------------------------------------------------------------------------------------------------SSGMDFRAMLKKRRYQKWDKDEQDPNWGDLKETEKPLPALKKVERKVESFLSPLIDQFAKEGKDKKVVFEARFSKPNCKPKWLFRKDEVFTGSKFKFKQENDTYQLIITTPKVEDTGKYTIEIGGVSSTAFLNVEEADPTYTFTKPLKKKLEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FTQHETTLECSVSSSMANVHWFKNNTKLESDDPRYLISKDINGNLKLIIKDSVLDDAGLYRCQLDKQPDK---------------------------------------------------------------------------------------TECNLKVTEYPYKFVKVLKSQQCIEKDTVTLACEIDDAMGEVQWLRNGEEIKPDKRIQIVKDGRKRKLVIKDCKVTDAGQFKCTTNADTTESEIIIN-YQNRFNKKLKDTEAVEREKLILDIELQDQTAPCDWKFNGEPIVPSESIEIKNMG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGKHQLIFSSLDMSNEGEITCESGQLSSKCKLSIRKGESRPNIDCPDKFSGPISAPVLLEVPFKVSGTKQTPVEAKLFKDGK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLPVKDVEVAVTDDKVTFKIKKPSRDLSGPYQIKISNGQGEDTKDVQIICQDVPQPPQDVDITDVYQTSCVVSFNPPSDDGGTPITKYVIERQDLS---------------------------------------------------------------------------------------------------KKHGWESVAEVLPSEPCLKKIDDLIPKKQYRFRIRAVNAIGQSDPATFKNTILAKDPWDEPGKPKAVDLTDWDKDHADLKWEAPETDGGDPITAYIVEYKEKFSNDWVSGKEVDGDARTATVDGLKEGQQYEFRVRAVNRAGPGEPSDKTKSIIAKCRFVKPFIVGEGLKN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTVKKGQTIRFDIKYDGEPEPAATWVKGTDNLKFDNQRICLDQLERNSSITIKKSVRKDTGKYKLVLSNSSGTIESEAQVVVLDRPLP--------------------------------------------------------------------------------------------------PGGPFEPEEIRASHIKMKWKRPDDDGGCEISGYALERMDEETGRWIPAGEVGPNETSFDFKGLTPNKKYKFRVKAINKEGESEPLETFDAIVARNPYDPPSPPSQPVIDDYDNKSVLLKWKRPPSDGGRPITHYIVEIKDKFAPSWSEVAKTDDPNPECNVEGLKEKMVYQFRVRAVNKAGPSEPSQPTDNHLCKHKNLKP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QIDRSTFKRVTIKSGRTHKWSVDVLGEPIPELHWSWRDDIPLTNGDRIKIENVDYHTDFSITNVLRKDSGFYTLKAENRNGIDRETVELVVLGKP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSPKGPLAVSDVTASGCKLQWKKPEDDGGVPIKEYVVEKMDTATG-----------------------------------------------------------------------------------------------------KWVRVGRSPGEKE---PPSFDVTGLSLGSEYMFRVSAVNEEGESEPLTTLVGVVAKDPFDEPNKPGTPEVTDYDNQSISLKWAAPNNDGGAPIQKYIIEKKNKNKTEWEKALEIP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GDQLEATVAGLQEYGEYQFRVIAVNKAGLSPPSDASVPQIVKYKKLKP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RIDRSNLKPLLIRAGKPIRYDVNVRGEPAPVITWYQNDKELKPEELPSSSEIKN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IPYNTKISIIETVRKHTGIYKIIAVNEHGQDEATVEVNILAPPSKPRGPLDVKDVTKDSCKLKWKKPEDDGGKPISAYQVEKFDKKQ--------------------------------------------------------------------------------------------------GRWVPLGRTSANDTEFDVKGLQEGHEYQFRVKAINEEGESDPLDSDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIIAKNPYDAASKPGTPNIVDYNEHMVKLKWEAPRSDGGAPISGYIIEKKDKFSPIWDEILSTNTSVPEATVEGLVEGNIYQFRVRAVNKAGFSDPSDATEPHLAKPRNLKP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YINRDKMKP--------IKVRAGQPVKFDVDVKGEPAPSLTWFLKETELTSTGQVRLENIDYNTKLTLLDTDRKQSGQYKLRAENINGVDEAVVEVIILDKPSKPEGPIEVSDIHKEGCKLKWRKPKDDGGIPITGYVIEKMDTATGKWVPAGSVDPEK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDIEIKGLDPNHRYQFRVKAVNEEGESEPLETESAITAKNPFDVSAPPGLPELEDWDEHHVKLKWEPPIRDGGSPITNYIIEVMDKDSGEFVKA-VETDSPVCKGVVKKLEEGQQYKFRVRAVNKAGPSDPSEQTNWHVAKPRFLKP--HIDRVNLKPVIVKTGLSISLDINIRGEPAPKVEWFFNNSSVTS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DEHSVKIDNVDYNTKFFVMRAQRSQSGKYIIKATNEVGEDEAELEVTVLGKPGKPKGPLQVNDITKHSCKLKWEKPDDDGGSPIDYYEIEKLDPHTGQWLPCGKSTEP-----------------------------------------------------------------------------------------------------EAKVIGLHEGKAYKFRVRAVNKEGESEDLETEKPIIAKNPYDEPDRP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKPEPTNWDKDFVDLAWDPPKNDGGAPIQKYVIQMRDKSGRAWVDSATVPGDKCNGTVTGVEEGHEYEFRIVAVNKAGPSDPSDVSKSVIAKPRFLKP-------------------------------------------------------------------------------------------------------HIDRKNLQKKIMRSGQMLHIDALIKAEPPAKVTWTYNKTEIKTSDHIKIENEDYKTTFIMPKVKRADRGIYIVTAKNDSGSDTVEVELEVLCKP------------------------------------------------------------------------------------------------SKPKGPLAVSNVTAETLHLKWEKPEDDGGDPIEQYLVERMDTETGRWVPVLTTKTPEADVTGLTEGKEYLFRVKAVNSEGESEP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVTDIPTKAKNPFDAADTPGKPQIVDWSGNHCDLKWRAPEDDGGASITGYIVERKDPNTGKWQKALETSTPDCKARVNDLIAGNKYQFRIMAVNKAGKSKPSEPSDQMTAKDRFAPP-----------------------------------------------------------------------------------------------------KIDRTNIKDITIKAGQHIRFDIKVSGEPPATKVWLHNKARLENDDSNYNIDMESYRTKLTVPISKRFHSGKYTLKAENESGRDEASFEVIVLDKPGPPEGPLRVTDVHKEGCKLKWNAPLDDGGLPIDHYIIEKMDVESGRWLPSG-RFKESFAELNNLEPSHEYKFRVLAVNTEGESEPLTGEQSVIAKNPFDEPGKPGTPEAVDWDKDHVDLVWRPPINDGGSPITGYVVEKREKGTDKWIKG--------------------------------------------------------------------------------------------------TEITIPCLGEECKATVPTLNENCEYEFRVKAINAAGPGEPSDASKPIITKPRKLAPKIDRKN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRTYNFKSGEPIFLDINISGEPAPDVTWNQNNKSVQTTSFSHIENLPYNTKYINNNPERKDTGLYKISAHNFYGQDQVEFQINIITKPGKPEGPLEVSEVHKDGCKLKWKKPKDDGGEPVESYLVEKFDPDTGIWLPVGRSDG-PEYNVDGLVPGHDYKFRVKAVNKEGESEPLETLGSIIAKDPFSVPTKPGVPEPTDWTANKVELAWPEPASDGGSPIQGYIVEVKDKYSPLWEKALETNSPTPTATVQGLIEGNEYQFRVVALNKGGLSEPSDPSKIFTAKPRYLAP-----------------------------------------------------------------------------------------------------KIDRRNLRNITLSSGTALKLDANITGEPAPKVEWKLSNYHLQSGKNVTIETPDYYTKLVIRPTQRSDSGEYLVTATNTSGKDSVLVNVVITDKPSPPNGPLQISDVHKEGCHLKWKRPSDDGGTPIEYFQIDKLEPETGCWIPSCR-----------------------------------------------------------------------------------------------------STEPQVDVTGLSPGNEYKFRVSAVNAEGESQPLVGDESIVARNPFDEPGKPEN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKATDWDKDHVDLAWTPPLIDGGSPISCYIIEKQDKYGKWERALDVPADQCKATIPDLVEGQTYKFRVSAVNAAGTGEPSDSTPPIIAKARNKPP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IIDRSSLVEVRIKAGQSFTFDCKVSGEPAPQTKWLLKKKEVYSKDNVKVTNVDYNTKLKVNSATRSDSGIYTVFAENANGEDSADVKVTVIDKPAPPNGPLKVDEINSESCTLHWNP---------------------------------------------------------------------------------------------------PDDDGGQPIDNYVVEKLDETTGRWIPAGETDGPVTALKVGGLTPGHKYKFRVRAKNRQGTSEP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LTTAQAIIAKNPFDVPTKPGTPTIKDFDKEFVDLEWTRPEADGGSPITGYVVEKRDKFSPDWEKCAEISDDITNAHVPDLIEGLKYEFRVRAVNKAGPGSPSDATETHVARPKNTPP-----------------------------------------------------------------------------------------------------KIDRNFMSDIKIKAGNVFEFDVPVTGEPLPSKDWTHEGN-MIINTDRVKISNFDDRTKIRILDAKRSDTGVYTLTARNINGTDRHNVKVTILDAPSVPEGPLRNGDVSKNSIVLRWRPPKDDGGSEITHYVVEKMDNEAMRWVPVG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DCTDTEIRADNLIENHDYSFRVRAVNKQGQSQPLTTSQPITAKDPYSHP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DKPGQPQATDWGKHFVDLEWSTPKRDGGAPISSYIIEKRPK-FGQWERAAVVLGDNCKAHVPELTNGGEYEFRVIAVNRGG-PSDPSDPSSTIICKPRFLAP--FFDKSLLNDITVHAGKRLGWTLPIEASPRPLITWLYNGKEIGSNSRGESGLFQNELTFEIVSSLRSDEGRYTLILKNEHGSFDASAHATVLDRPSPPKGPLDITKITRDGCHLTWNVPDDDGGSPILHYIIEKMDLSRSTWSDAG-MSTHIVHDVTRLVHRKEYLFRVKAVNAIGESDPLEAVNTIIAKNEFDEPDAPGKPIITDWDRDHIDLQWAVPKSDGGAPISEYIIQKKEKGSPYWTNVRHVPSNKNTTTIPELTEGQEYEFRVIAVNQAGQSEPSEPSDMIMAKPRYLPPKIIT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLNEVRIKCGLIFHTDIHFIGEPAPEATWTLNSNPLLSNDRSTITSIGHHSVVHTVNCQRSDSGIYHLLLRNSSGIDEGSFELVVLDRPGPPEGPMEYEEITANSVTISWKPPKDNGGSEISSYVIEKRD----------------------------------------------------------------------------------LTHGGGWVP---------------AVNYVSAKYNHAVVPRLLEGTMYELRVMAENLQGRSDPLTSDQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVVAKSQYTVPGAPGKPELTDSDKNHITIKWKQPISNGGSPIIGYDIERRDVNTGRWIKINGQPVPTAEYQDDRVTSNHQYQYRISAVNAAGNGKTSEPSAIFNARPLRE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPRFYFDGLIGKRIKVRAGEPVNLNIPISGAPTPTIEWKRGDLKLEEGKRISYETNSERTLFRIDDSNRRDSGKYTVTAANEFGKDTADIEVIVVDKPSPPEGPLSYTETAPDHISLHWYSPKDDGGSDITGYIIEFTEFGVDDWKPVPGTCPNTNFTVKNLVEGKKYVFRIRAENIYGASEALEGKPVLAKSPFDPPGAPSQPTISAYTPN--------------------------------------------------------------------------------------------------SANLEWHPPDDCGGKPITGYIVERRERGGEWIKCNNYPTPNTSYTVSNLRDGARYEFRVLAVNEAGPGHPSKPS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPMTAEHQRYRPDPPEPPKPDRITRNGVTLSWRPPRTDGKSRIKGYYVEMRPKNGK------------------------------------------------------------------------------------------------------DWKTVNDIPINSTVYTVPSLKEGEEYSFRVVAEN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVGRSDPSKPSQPITIEEQPNKPCMELG--KVRDIVCRAGDDFSIHVPYLAFPKPNAFWYSNDNMLDDNNRVHKHLTDDAASVVVKNSKRADSGQYRLQLKNTSGFDTATINVRVLDRPSPPTR-LRADEFSGDSLTLYWNPPNDDGGSAIQNYIIEKKEARSSTWSKVSSFCTVPFVRIRNLVLNKEYDFRVIAENKYGQSDPAN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSEPILARHPFDIPNTPGIPHGIDSTEDSITIAWTKPKHDGGSPITGYIIEKRLLSDDKWTKAVHALCP-DLSCKIPNLIENAEYEFRVAAVNAAGQSAYSGSSDLIFCRRPPHAPKIT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDLSIRDMTVIAGDEFRITVPYHASPRPTASWSLNGLEVIPGERIKFDSNDYASMYYNKSAKRDETGSYTITLTNNKGSDTASCHVTVVDRPLPPQGPLNAYDITPDTCTLAWKTPLDDGGSPITNYVVEKLDNS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSWVKISSFVRNTHYDVMGLEPHYKYNFRVRAENQYGLSDPLDIIEPIVAKHQFTVPDEPGQP-KVIDWDSGNVTLIWTRPLSDGGSRIQGYQIEYRDILNDSSWNAYDYIIKDTKYQLYNLINGSEYEFRIKAKNAAGLSKPSSPSLRFKLKGKFTVPSPPGAPQVTRVGKNYVDLKWEKPLRDGGSRITGYIIERRDIGGAVWVKCNDYNVLDTEYTVMNLIEMGDYEFRVFAVNSAGRSEPSLCTMPIKVCEVLGGKKPDWITRLQDKVAPFGKDYTLQCAASGKPSPTARWLRNGKEIQMNGGRMTCDSKDGVFRLHISNVQTGDDGDYTCEAMNSLGFVNTSGYLKIGSPPIINR---CPSELKLPEGDNSKIKIFYSGDQPLTVILKKNNEVICDSNDDTHVKVNIFDDYVAIYIRNIVKSDGGPYQIEFTNESGSATGEFYVHITGMPSAPTGPMGISYINKNSCMLNWRPPSYDGGLKVSHYVIERKDVSS-PHWITVSSTCKDTAFNVQGLIENQEYIFRVMAVNENGMGPPLEGLNPIRAKDPIDPPSPPGSPQITEIGGDFVHLEWEKPESDGGAHIQGYWIDKREVGSNTWQRVNATICAANQINCINLIEGRQYEFRIFAQNVAGLSTESSASQAVKIIDPQAASPPLIVKPLRDANCIQNHNAQFTCTINGVPKPTISWYKGAREISNG--ARYHMYSEGDNHFLNINDVFGEDADEYVCRAVNKAGAKSTRATLAIMTAPKLNVPPRFR--DTAYFDKGENVVIKIPFTGFPKPRIHWVRDGENIESGGHYTVEVKERHAVLIIRDGS-HLDSGPYRITAENELGSDTAIIQVQISDRPDPPRFPLIESIGTESLSLSWKAPVWDGCSDITNYYVERREHPLSSWIRVGNTRFTSMAVSGLTPGKEYDFRIFADNVYGRSDASDTSTLIKTKESVKKKPIERKWEIDANGRKLRGKADGPVKDYDSYVFDIYSKFVPQPVEISQQSVYDRYDILEEIGTGAFGVVHRCRERSTGNIFAAKFIPVSHSVEKDLIRREIDIMNQLHHQKLINLHDAFEDDDEMILILEFLSGGELFERITAEGYVMTEAEVINYMRQICEGIRHMHEQNIIHLDIKPENIMCQTRSSTNVKLIDFGLATRLDPNEVVKITTGTAEFAAPEIVNREPVGFYTDMWATGVLSYVLLSGLSPFAGDNDVQTLKNVKACDWDFDVESFKYISEEAKDFIRKLLVRNKEKRMTAHECLLHPWLTG------------------------------------------------------------------------------------------------------DHSAMKQEINRDRYLAYREKLRRKYEDFERFLLPIGRLSEYSSLRKLLMEKYKIHDAVFDRR------------------------------------------------------------------------------------------------------------------------QAAPRFVIRPSSQFCYEGQSVKFYCRCIAIATPTLTWSHNNIELRQSVKFMKRYVGDDYYFIIN-RVKLDDRGEYIIRAENHYGSREEVVFLNVQPLPKEQPRYRTES----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPVRRREPLPYTFWQEESE------------------------------------------------------------------TAPSFTFLLRPRVMQARDTCKLLCCLSGKPVPNVRWYKDGRELS-KYEYAMTHSDGVVTMEIIDCKPSDSGKYSCKATNCHGTDETDCVVIVEGEWVTPEQAQLAHN--------------------------------------------------------------------------------------------FLYSGDRKYIEQPIKPAPLP----------IVTSRQYTSSSVQNTSEPQGDKVNVSNSNSSGISNKKKYASNSLQAPGSPSRSRSATKELILPP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDSLMCKPEFTKPLHDLTIHDGEQLILTCYVKGDPEPQISWSKNGKSLSSSDILDLRYKNGIATLTINEVFPEDEGVITCTATNSVGAVETKCKLTIQPLDKNINKRK-------------------------------------------------------------------------VNAGDNAPKIVSHLESRFVRDGDAVN----LACRIIGAQHFDVVWLHNNKEIKPSKDFQYTNEANIYRLQIAEIFPEDGGTYTCEAFNDIGESFSTCTINVTVPGDETKQPSFVKFPTSVSVLEGEGTTFECEIDSELLNLVWLKDGKPIDETLPRYSFTKDGHRYSFAVAKCNMDDVGQYQAKAVSGKAESICAFSMNVHTAES----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . .*.*:** : : :*: : :**:: .**: .: ***.*.:: *. : ::.: : .::: . *.: :: .* * *: **.*: *. :.: .::*. . . :* * .. : :** *: : :** * . * : *:::* :. ..:*:**. . .:..:.: **:::* ::*.*. ..*: *.:..* * ... : * . *: * * * :: * *::*: * * ::* : .*:*..: ***.:. . ::::* *:* .. .*. *:*...*.* * :*.*.*::.: ...::* * :.*** ** * :::: ** : . * .::** .* ** :..: :*: . : **::. : **.*:* *:* * *.:.:. :*:.: .* * :** : . .*: : ::*: :..* *:*::.: :...** ** : : . : *.:: * .::.*.* *::**: * .:. .*.: . : *:* .* : .. .*. *:***** ..* .* *:::*: *....* :* : : : **: .. :**:* *:* *:*: *: ... : * * : .: : :*: :. ::* :*.. * :*** :.:: : :..:. . ::: . .*::.*.* *. * ** *: ::: * ::* . ::* ** : : .... * . * .. :::* :.. :: :. : :* . ** * : .. . .:.:* .:* .*.* :..*:*::. . **. : : : :..* ::**:** * ::*** *::*. :* * *: * . * *.: .:. : . . .* : :. :: : *: : 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:***:.*:**::** :.. : *. *. :**.. :: :** *. .* *** * *: * . * *::*:...:* * * ****:.*: :: *.*:**.*: **** *:.**:*:* *:* :. . :: .*.***:. .*****:* * .. *:**:.:..* * . .* ::* .: : * *:**: * . * . * *:*:* :* ** ..:: * : : : ..:* * *:*.* *** *: :.:..***:*.** ***:*. :* : * *:*. *::***: * :**:** : *: :*: . .**:*:: :**:***..** * .:***:: :: * : * *..* . **. :: : * *: *::***: ** ***:::**.* * .*.: * . .. . * ** ***:** * * ** * **:.* :: *: : *. : * : * ::.* ::.** : *:* *:.* : :. ** :. * . ..: .:: :. :*:* *.: **** : ::::******** **: .:** :***:.*:*** :***.::.*:: **: :::**. * .* : : .* *. : * :**:** *** * ..* ..: .****. :..**.*. **:*. ** :*: *.:* :*** * ** :*:** :: *:*: :.: :. : :*.* :****:.****** * **** :::* : .*.. :. : * ::.** *. *:*::* .* *.*:*.* :..* *:*.: : :....:: : *.: ::...***** * . : : * :*.:. ** *:**: : * .* : * *:*:**.:** * ** * . :** * .: ..*.*.* ***:. :* **:**** **.*:.* .. ::** * **.*.:*.* *.: : .*:*:** **. *..* :*:*: . .*::** ..: .***:.* * *****::* * .*. *.. * **:.*: * **.* *:*..:* *.:**:* *.:** ..*: * :* * *:.. **:.** . .* ***..*: ****.*** * * :.* *:* :. ..: *:* :* :* . : *.*:**. *:*.** . * *:. * :: *.:.:*: *.* :::.**:* *.***:* * *:**:*..* ::.* *:.**.* * :.....*.:* .* * *:*.**: * ***:**:*: :::*. :.* . . ::: :*. ** *** :**::* *.* : ****:**:.* **. ****. :.: :: * * ****: ***. *:.*:::** .. :**:. : * *:..*:*..:*:***:***:**:* * :*::* **.*.::* . * :. : : * ** ..:.:* . * *:*** : * :: .**:..::: .: :.:. :**.* : *.* .*: : : :* ::*:* ** **:: :: . : *::*:.* ***:*::.****: * .:* .*.* **.* * **: : :*:*** ****:*:*.**. **: .* :. *: *.:* :*:* ...*:* *:** .*****: ** ** :: .*. . . *. * * : .*: .:**:*** *:* .***:.*..* . *. * ** ** :: :.*: * *:**** ***..* ** :* *: *.:.* *.*. .: * ::*: .*:* :******* *.:* *.* :*.:*. . * : *. ..: * .: :*: *.* *:* * :* * ***: . : . .*.. .. * : . : *:* *** * *.:* *::*. * : :.* :: .: . *.. :::::* * :: :.:::: :*:. * :.: : . * :: *:..* *:::::* *:. . : *.* . *. ****: *. : *** ::.*:.*: *** :::**:*: :... ..* ***: . *: .: .* ** * *** * * *:. *** . : *.*:: *. **.* ** : * : *: * *****:*:.*::::** .*.* *.: . :. ***** :****: .:*:.* * *. *:.:. . . ..* : : **: * : ** :.*.:.* *** :.**: .:** . :*. * * * .* .:** * **.*:.*: * *:* : ...*:::* :. .:.: :** * *****:* *.* * * :. : *:..*** * *.. .: *:: :* : *:* * : *:*.:* * ::::::* ***** :..:. :*:.*:*. *. ** *.:*** **: . . *:***::* * :* .* ..*:**::*:* :* *..*:.* ***. .: . :**. * : . .:. . . :.:*::* * *::* * **:**** * *: . : ***: *. .:: *:::**.*:* :*:::: **::**. :*:::*:**:** ::****.:..: :.* *::.*::*:**.:..:*.:** *:**:****: *** .: :*:*:** * :*.*.: .:: :.*: ***: ::: *. ****: *.* ******:.** .:.: * ::*: .:: ** *:*: ** ** **: :***::::.**** *.* ****. ::* : .* * * :* :. .* ** :*::: : : ** * * :. * ***** * * .*..***.*.::. * . :: : * *** : . :* * * : * * ** . ..*:*: * : .::::. : : * .* * :::::* ** :*: :*.: : . :. ::: :..**..:*:**::* **. . : *::.**:*:**:**:..*.*.* . .** :* . ..: * * *. :* .: ::.*: :. . *:* : ** :: ::.: .* : ..*:.*:... .: ::. ..:. : . : .::: * : ** :.: .** :.. *:* *: ... :. ..*:*.* *:*:**:::... .* .: * * :. ..* *: :**. **.*:*.:.*****:.:... :: .::.: : :: :* * : . :. . : * ** *: *. *: *::::* ... * * : .: * :* . :.. .* ::*:. : :. *:*:. * * .: **:.. * **:..* : ..: . .. *.::. : *:: : :. :.* *:* ** . :.:. .: *: * . . ", "identical_positions": 2768, "similar_positions": 3237, "identity": "7.8%" }, { "cls_id": "homologset.agr.RGD:621115", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08635-1", "uniprot_id": "SAST_RAT", "id": "P08635-1", "name": "S-acyl fatty acid synthase thioesterase, medium chain", "aln": "METAVNAKSPRNEKVLNCLYQNPDAVFKLICFPWAGGGSIHFAKWGQKINDSLEVHAVRLAGRETRLGEPFANDIYQIADEIVTALLPIIQDKAFAFFGHSFGSYIALITALLLKEKYKMEPLHIFVSGASAPHSTSRPQVPDLNELTEEQVRHHLLDFGGTPKHLIEDQDVLRMFIPLLKADAGVVKKFIFDKPSKALLSLDITGFLGSEDTIKDIEGWQDLTSGKFDVHMLPGDHFYLMKPDNENFIKNYIAKCLELSSLT--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R197-1", "uniprot_id": "SAST_MOUSE", "id": "Q8R197-1", "name": "S-acyl fatty acid synthase thioesterase, medium chain", "aln": "METAVYAKSTRNEKVLNCLCQKPDALFKLICFPWAGGGSTHFAKWGRKINGLLEVHAVRLAGRETRFEEPFSNDIYQIAEEVVTALLPIIRDKAFAFFGHSFGSYIAFITALHLKEKYKMEPLHIFVSSASAPHSEFRPQVPDINKLSEEQIRDHLLIFGGTPKHLIEDQDFLKQCIPLLKADVDIVKKFIFDKPSKALLSRDITCFIGSEDVVKDIEGWKDITSGKFDVLKLPGDHFYLMEPNNEDFIKNYIVKCLELSSLDYF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NV23-1", "uniprot_id": "SAST_HUMAN", "id": "Q9NV23-1", "name": "S-acyl fatty acid synthase thioesterase, medium chain", "aln": "MERGDQPKRTRNENIFNCLYKNPEATFKLICFPWMGGGSTHFAKWGQDTHDLLEVHSLRLPGRESRVEEPLENDISQLVDEVVCALQPVIQDKPFAFFGHSMGSYIAFRTALGLKENNQPEPLHLFLSSATPVHSKAWHRIPKDDELSEEQISHYLMEFGGTPKHFAEAKEFVKQCSPIIRADLNIVRSCTSNVPSKAVLSCDLTCFVGSEDIAKDMEAWKDVTSGNAKIYQLPGGHFYLLDPANEKLIKNYIIKCLEVSSISNF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40ECQ8-1", "uniprot_id": "A0AB40ECQ8_DANRE", "id": "A0AB40ECQ8-1", "name": "S-acyl fatty acid synthase thioesterase, medium chain", "aln": "---MWNILSRGMDKVITCFNKCPDASVRLICFPWAGGGSIHYARWAKTLPSSIEVYSVRLPGREGRTKEPFFQNMQEILDEVIGVLLPQLKEKPFALFGHSFGAMICFAFAEHVKKVHNLEPIHMFLSGASAPYSEARLQAPRRSHLSDDEFLIWVTSIGGTPPEILANAELAKLFLPALKADLYVADSYRCSRPSKPFLSCPVSCFDGKEDSPHDLQAWKIMTSGDFTVQMLPGSHFYLKEAANEKYILDIITKHIETAEMDYL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::.*: : *:* .:****** **** *:*:*.: . :**:::**.*** * **: ::: :: :*:: .* * :::*.**:****:*: *.: * :*: : **:*:*:*.*:. :* : * ..*::::. : :**** .: :. : * ::** :. . . ***..** :: * *.** :*::.*: :***. : ***.**** .. **. * : * * :* :.: ", "identical_positions": 83, "similar_positions": 92, "identity": "31.32%" }, { "cls_id": "homologset.agr.RGD:621116", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NZA9-1", "uniprot_id": "TAF9B_MOUSE", "id": "Q6NZA9-1", "name": "Transcription initiation factor TFIID subunit 9B", "aln": "-----------MEPAK------MAPIKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLVK-----KGPNQGR---LVPRLS--AVSSRPTTPPVAPPQAVSGPNKAATPVSVTSQRFAVQIP----------PSQSTPAKPAPAATAVQNVLINPSMIGPKNILITTSMVSSQNTATDSNPLKRKHDDDDD-------NDTM--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62880-1", "uniprot_id": "TAF9B_RAT", "id": "Q62880-1", "name": "Transcription initiation factor TFIID subunit 9B", "aln": "-----------MEPSK------MAPLKNAPRDALVMAQILKDMGITDYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPT-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLVK-----KGPNQGR---LVPRLSVGAVSSRPTTPTVAPPQAVSVPNKVATPVSVTSQRFAVQIP----------TSQSTPAKPAPAATSVQNVLINPSMIGSKNILITTNMVSSQSTATDSNPLKRKHDDDDDDDDDDDDNDTM--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HBM6-1", "uniprot_id": "TAF9B_HUMAN", "id": "Q9HBM6-1", "name": "Transcription initiation factor TFIID subunit 9B", "aln": "-----------MESGK------MAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPN-----VDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIK-----KGPNQGR---LVPRLSVGAVSSKPTTPTIATPQTVSVPNKVATPMSVTSQRFTVQIP----------PSQSTPVKPVPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEANPLKRKHEDDDD-------NDIM--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q27272-1", "uniprot_id": "TAF9_DROME", "id": "Q27272-1", "name": "Transcription initiation factor TFIID subunit 9", "aln": "-----------MSAEKSDKAKISAQIKHVPKDAQVIMSILKELNVQEYEPRVVNQLLEFTFRYVTCILDDAKVYANHARKKT-----IDLDDVRLATEVTLDKSFTGPLERHVLAKVADVRNSMPLPPIKPHCGLRLPPDRYCLTGVNYKLRATNQPKKMTKSAVEGRPLKTVVKPVSSANGPKRPHSVVAKQQVVTIPKPVIKFTTTTTTKTVGSSGGSGGGGGQEVKSESTGAGGDLKMEVDSDAAAVGSIAGASGSGAGSASGGGGGGGSSGVGVAVKREREEEE------FEFVTN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05027-1", "uniprot_id": "TAF9_YEAST", "id": "Q05027-1", "name": "SAGA complex/transcription factor TFIID complex subunit TAF9", "aln": "MNGGGKNVLNKNSVGSVSEVGPDSTQEETPRDVRLLHLLLASQSIHQYEDQVPLQLMDFAHRYTQGVLKDALVYNDYAGSGNSAGSGLGVEDIRLAIAARTQYQFKPTAPKELMLQLAAERNKKALPQVMGTWGVRLPPEKYCLTAKEWDLEDPKSM-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :..*:*. :: :* . .: :** :* *:::*:.**. :*.** :* .:* . . :. :*:*** : .*. . :..: .:* :*. .** : * ****::****. :: *. . ", "identical_positions": 34, "similar_positions": 54, "identity": "11.33%" }, { "cls_id": "homologset.agr.RGD:621117", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N2Q7-3", "uniprot_id": "NLGN1_HUMAN", "id": "Q8N2Q7-3", "name": "Neuroligin-1", "aln": "--------------------------------------------------------------MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDD-----------------------------------------VDPLVATNFGKIRGIKKELNN-EILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVS---SYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKGGPLTKKQTDDLGDNDGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTG----DQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVS------DTVELVECLQKKPYKELVDQDIQPARYHIAFGPVIDGDVIPDD-------------PQILMEQGEFLN------------------------------------------YDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADR-HNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSP-----------------------------TYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPN-RFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVP-----------HLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQQPSPFSVDQ-----------------------------------------------------------------------------RDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRR-----------------------------------------------------------------------CSPQRTTTNDLTHAQEEEIMS-----------------LQMKHTDLDHECESIHPHEVVLRTACPP--------------------------------------------------------------------------------------------------------------------------------DYTLAMRRSPDDVPLMTPNTITMIPN-----TIPGIQPLHTFN-------------------------TFTGG-----------------------------------------------------------QNNTLPHPHPHPHSHSTTRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62765-1", "uniprot_id": "NLGN1_RAT", "id": "Q62765-1", "name": "Neuroligin-1", "aln": "--------------------------------------------------------------MALPRCMWPNYVWRAMMACVVHRGSGAPLTLCLLGCLLQTFHVLSQKLDD-----------------------------------------VDPLVTTNFGKIRGIKKELNN-EILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVS---SYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKG--------------------DIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTG----DQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNVS------DTVELVECLQKKPYKELVDQDVQPARYHIAFGPVIDGDVIPDD-------------PQILMEQGEFLN------------------------------------------YDIMLGVNQGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADR-HNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSP-----------------------------TYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPN-RFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVP-----------HLHNLNDISQYTSTTTKVPSTDITLRPTRKNSTPVTSAFPTAKQDDPKQQPSPFSVDQ-----------------------------------------------------------------------------RDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRR-----------------------------------------------------------------------CSPQRTTTNDLTHAPEEEIMS-----------------LQMKHTDLDHECESIHPHEVVLRTACPP--------------------------------------------------------------------------------------------------------------------------------DYTLAMRRSPDDVPLMTPNTITMIPN-----TIPGIQPLHTFN-------------------------TFTGG-----------------------------------------------------------QNNTLPHPHPHPHSHSTTRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99K10-1", "uniprot_id": "NLGN1_MOUSE", "id": "Q99K10-1", "name": "Neuroligin-1", "aln": "--------------------------------------------------------------MALPRCMWPNYVWRAMMACVVHRGSGAPLTLCLLGCLLQTFHVLSQKLDD-----------------------------------------VDPLVTTNFGKIRGIKKELNN-EILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVS---SYVQDQSEDCLYLNIYVPTEDGP-LTKKHTDDLGDNDGAED-------------------EDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTG----DQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNVS------DTVELVECLQKKPYKELVDQDVQPARYHIAFGPVIDGDVIPDD-------------PQILMEQGEFLN------------------------------------------YDIMLGVNQGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADR-HNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSP-----------------------------TYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPN-RFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVP-----------HLHNLNDISQYTSTTTKVPSTDITLRPTRKNSTPVTSAFPTAKQDDPKQQPSPFSVDQ-----------------------------------------------------------------------------RDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRR-----------------------------------------------------------------------CSPQRTTTNDLTHAPEEEIMS-----------------LQMKHTDLDHECESIHPHEVVLRTACPP--------------------------------------------------------------------------------------------------------------------------------DYTLAMRRSPDDIPLMTPNTITMIPN-----TIPGIQPLHTFN-------------------------TFTGG-----------------------------------------------------------QNNTLPHPHPHPHSHSTTRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VIC6-1", "uniprot_id": "Q9VIC6_DROME", "id": "Q9VIC6-1", "name": "", "aln": "MVMLLSKRQLPPSAATRTRRKVPPTRRRSTWALSSLLALVVLDICIARCLAAGISYSSNSGNLSTSQKSPSSANNGGLVLIGSSSATSSSVPSLSLTSSSSAGLSSPGSSSSSSSSSTSTSGSNSNRSSRPTSNNSNSNSNYSPNHDQLPAQLSSRIINTRNGAISGVIVQLDG-RHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSG---SGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYS-KLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISS-------MAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCAS----DL-PHAHLMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGG-------DYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFN-SGDVQYGIEADRRSRILKAYVRNTYTFHLN--EIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHR-----------------------------NSYLYVFDYQTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGS--RQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIP-----------DLHKPGGDNVPAAHHQLHDDDDEDNNIPSDASVKPLNPPYISRAANAAAMANFTIFTNQVFSLLNLSSPSSSLQRNGTRYGGG-----KIYPDDMMD------GDHAGG--------AASASQD-------SDGFAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLSEPRPQTKLKRQ------------------------ENGQMPNNICGDLETLTIHA---------------------KSDPATILSHHHAMQHHQLP------------------PPEFADIPHRAPPPPKHMKSLQDP------------------------------GGGGSVSG--AVGVSG--------VVQMPPP---------------HALQVMGNQCGTLTKKS------------------------------CMKQTQ----AQAQQHSPAQQQQQQQQQQQQ-------HVVT--HQQHLQN---------------HHNQSMTTVLTTAGG-----LVVPTPP------TVPVIVASTTQHQQH--------------------------QQQHQQQQHQQQQQQQQQQHPLMDELRV-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A6H2EDS1-1", "uniprot_id": "A0A6H2EDS1_DROME", "id": "A0A6H2EDS1-1", "name": "", "aln": "--------------------------------------------------------------MGESQ----------LLLLLR---------LLLLPTVLISWMHCAGASTADIYKG---------------------------------ARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEK------------------------------------------KLPVIVFIHGESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTS-------PTMVRG-LFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINR-HHEQIVDCLRDVPLEDLYLADIQAPNFLTSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFS-AHDIQNGFEGERRDKIIRTYVRNAYNYHLN--EIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLRLIP-----------ELHRAGMEDVIARHNLFRNHDDMD---LYEGPVKP-DPFGISTAAGASGSSSSSSSSSRLLLVDEQLMMKKGRGLNGSAYLNGILGVTTVEPNNMYTTCIPIGGNYSSSGGVFAPTTLANASSDTLASGFEAAGYAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLEVKTLQKQYQQRSLHQQV----PYPPEPIKHAHYHMGHSQSSANVIVDVESHQDQAGQAAMLLQAAAAAAAAAANDVKPPPPHICSNTGMQQQQQVGGGSGGALNNGGIEGSKVTTDNLGNVTYSTSSKQQQQHQQQQQQQQREHMQIKGMTGTQTFGRSGSGSGGGAGGGAGSASGGASVVVSGSSVSYNPGMMTLPKSGGLHHAATLNYARNTTALNMSGGGTALVDSRGNVLLTSTAVGPGMAGTGAGGGSSGGGGGGDCMTLPRNLGLAAAGRHNPTTELQQYQQQQQSSKHQSNGAVLTGMQSHHIRGPRPPLRTASSTTTNSSSNNSAMGVAVGVGGGVGNMLLDQTPSGGSSSSGVSSAPSSSKGHHTHSHSHAAHLVHSHGDGLVLTSASPVGGQQQQHPQQHQHPQQQQQVPQAAMDEMREFYAPKQPDDDGQLNGTPVDADAATQVVGAGRTGGMGAPPISASDHKQRQLKKLRFKREIHALALEGGDVARGYCSCDEQWTNSSSPTSTTTSATMSPTLPAGGSAGDAGRHATGNGPGNSSAGSSGIVKMAAAPGKRSERLKQQHHVRFSDEKNFSD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIC7-1", "uniprot_id": "Q9VIC7_DROME", "id": "Q9VIC7-1", "name": "", "aln": "MKFRLAAFWLFLLTVGGNHKLLSHVSPMGVAAEKQPLHKGNELENAMKLREAPKQSRVIGDITTTIQPDSDPGRSIGHQALRRAKAPPPSLELHFRQNLNKLFAGDETTHVGHTNATDNTTAAVLATDEGSSEHEPSTTHHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLS--PHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTP-----------------------------------------KQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPS---IDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVS---------PVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTSLGPIVDGHVIPNQ------------PYKVMGHYTEHFS-----------------------------------------RYDLLFGITESESYHTLA-ALALEEGLRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRR-----------------------------NYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKG-IFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQLQKPGQEVITGHMSKYGPRDHGAEDPVRTLKLLLQEPSLAGPTQSGESTETAAENMYNAPPTFGHVHKMQGGSDFEDLVTSTN-----------------------------------SLESGEDHPQAPPETVAKSEATMQLLIALITIIIVLNLLIYGTFLLRQRRRRAKALPFPAPKLGGTILSYDGANDEELKRCSKSRDGDDSFVLEMTRKSNTYEAIKTGQRSLSCSTVDTHTKVCEWMSSQEAPKSGSFNTATPPPQPILSDGRLIICQDIEVADAALLIPQHMHEPQHYEMLLQRQHSALTEPSDEILQQQYPLRNHSHSHSDPVDMILAADEQVTSFVHADDVDINVTSRDDSDGLEVIPLTSAQQLELLRQRNYPKVLPTEQDLINSSYKRNSLPPQNFN----------------------APLPPPRTISNTLGRRRRDSSNITTSPLQVARDCGGEDEDLKEPQITQNTLIVGPIVPKSPASSLKRVKRMPESSAMTALSG--------------------------------------------------------SFQSFEAVPPAHETTPPQGGERTECIYAIRP--------SPGSCSWAAPNGDLYAQPMKSSSRNSLIPRPTKPAESQSQATPAGPAGESLGSTGMATASRIPQLQRQASGKDLQARTATDNTANPLGCQPRTDSTISSGSSASYASTTDSSSSSSTGTVRTELQQFQPAPGRSITTNI----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. * : *: :: * * : *:*** .*. : ** *. .. *..:: : : .*****.: : . . :. .::. :********:: * : .*:*::** *: .:** ******:***:::*:*:*****:**** .. .**.*:* : **:* .:** **** :*: * .:*.:*:: * * **:*** **:. : *: :. : :* : * ::.**:. .:: ..: ::** :** ** **:: *: .*. . : *. . . : :: . : . *. : ::* : *.* : : : *:*.* :: . . *:::.:::* *: . *:: : ** .** :*:**.:**:*: . : * :. : **.:. * : ::* :.:* . :* .*:. . . .. . . . .: :.: **: ::.**:* :. . :: : * . .. . . . : : . : : . :: : . .* . : * : ", "identical_positions": 133, "similar_positions": 205, "identity": "8.19%" }, { "cls_id": "homologset.agr.RGD:621118", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62888-1", "uniprot_id": "NLGN2_RAT", "id": "Q62888-1", "name": "Neuroligin-2", "aln": "---------------------------------------------------------------------------------------------MWLLALCLVGLAGAQRGGGGPGGGAPG-GPGLGLGSLG--------------------EERFPVVNTAYGRVRGVRRELNN----------------EILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDN----LEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPP---------------------DTDIRDSGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQ---AAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEG--LFQKAIAQSGTAISSWSVN---YQPLKYTRLLAAKVGCDRED------STEAVECLRR-KSSRELVDQDVQPARYHIAFGPVVDG------------------DVVPDDPEILMQQG------------------------------------------------EFLNYDMLIGVNQGEGLKFVEDS--AESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWAD-RDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFP------CNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRTPGPGTSGTRRPPPPA---------------------------TLPPESDIDLGPR-AYDRFPGDSRD-------------------YSTELSVTVAVGASLLFLNILAFAALYYKRDRR-------------------------------------------------------------------------QELRCRRLSPPGGSGSGVPGGGPLLPTAGRELPPEEELVSLQLKRG-GGVGADPAEALR------PACPPDYTLALRRAPDDVPLLAPG----------------------------------ALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZK9-1", "uniprot_id": "NLGN2_MOUSE", "id": "Q69ZK9-1", "name": "Neuroligin-2", "aln": "---------------------------------------------------------------------------------------------MWLLALCLVGLAGAQRGGGGPGGGAPG-GPGLGLGSLG--------------------EERFPVVNTAYGRVRGVRRELNN----------------EILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDN----LEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPP---------------------DTDIRDSGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVVTLNYRLGVLGFLSTGDQ---AAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEG--LFQKAIAQSGTAISSWSVN---YQPLKYTRLLAAKVGCDRED------STEAVECLRR-KSSRELVDQDVQPARYHIAFGPVVDG------------------DVVPDDPEILMQQG------------------------------------------------EFLNYDMLIGVNQGEGLKFVEDS--AESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWAD-RDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFP------CNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRTPGPGTSGTRRPPPPA---------------------------TLPPESDIDLGPR-AYDRFPGDSRD-------------------YSTELSVTVAVGASLLFLNILAFAALYYKRDRR-------------------------------------------------------------------------QELRCRRLSPPGGSGSGVPGGGPLLPTAGRELPPEEELVSLQLKRG-GGVGADPAEALR------PACPPDYTLALRRAPDDVPLLAPG----------------------------------ALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFZ4-1", "uniprot_id": "NLGN2_HUMAN", "id": "Q8NFZ4-1", "name": "Neuroligin-2", "aln": "---------------------------------------------------------------------------------------------MWLLALCLVGLAGAQRGGGGPGGGAPG-GPGLGLGSLG--------------------EERFPVVNTAYGRVRGVRRELNN----------------EILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDN----LEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPP---------------------DTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQ---AAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEG--LFQKAIAQSGTAISSWSVN---YQPLKYTRLLAAKVGCDRED------SAEAVECLRR-KPSRELVDQDVQPARYHIAFGPVVDG------------------DVVPDDPEILMQQG------------------------------------------------EFLNYDMLIGVNQGEGLKFVEDS--AESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWAD-RDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFP------CNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRPP-AGAPGTRRPPPPA---------------------------TLPPEPEPEPGPR-AYDRFPGDSRD-------------------YSTELSVTVAVGASLLFLNILAFAALYYKRDRR-------------------------------------------------------------------------QELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRG-GGVGADPAEALR------PACPPDYTLALRRAPDDVPLLAPG----------------------------------ALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AU21-1", "uniprot_id": "A0A8M3AU21_DANRE", "id": "A0A8M3AU21-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MYLPHACKRDLGYAHNSEVTHTIALFWLALWITLASCQR----------------IDPGTKYPTVTTNYGKLRGIKKELNN----------------EILGPVEQYLGVPYATAPIGDRRFQPPEAPGSWQEVRNATQFAPVCPQNVHGVLPEIMLPVWFTDS----LDVAATYIQNQSEDCLYLNVYVPTEDGPLTKKHDESTLNRPR--------------------DEDIRDRRKKPVMLFIHGGSYMEGTGNMFDASVLAAYGNVIVVTMNYRLGVLGFLSTGDQ---SAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASCVNLLILSHHSEG--LFQRAIAQSGSAISSWSIS---YQPLKYTKILARKVGCTYGE------TADLVDCLRR-KNFRELVDQDIQPARYHIAFGPVMDG------------------DVVPDDPEILMQQG------------------------------------------------EFLNYDLLIGVNQGEGLKFVDDGG-TESEEGISAAAFDYTISNFVDNLYGYPKGKDILRETIKFMYTDWAD-RDNGEMRRKTLLALFTDHQWVAPAIATAKLHADYQSPVYFYTFYHHCQTETRPEWADAAHGDEIPYVFGVPMIGATDLFP------CNFSKNDIMLSAVVMTYWTNFAKTGDPNLPVPQDTKFIHTKPNRFEEVIWTKFNSKDKQYLHIGLKPRIRDNYRANKVAFWLELVPHLHNLHEEVFSTATTRLPPGTARTPHWKGQGPRTTRHPIP-----------------------------TFPSELDPDSSEQPRFPPFPSDTRD-------------------YSTELSVTVAVGASLLFLNILAFAALYYKRDKR-------------------------------------------------------------------------HEMRRHRLSPQRG-----------VAANDLAHSQEEEIMSLQMKHS-EHDAHHDMEPLRPHDILRPACPPDYTLALRRAPDDVPLMTPN----------------------------------TITMIPSTITGMQP-----LHAFNTFP----TSTGHNNTLPHPHSTTRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIC6-1", "uniprot_id": "Q9VIC6_DROME", "id": "Q9VIC6-1", "name": "", "aln": "MVMLLSKRQLPPSAATRTRRKVPPTRRRSTWALSSLLALVVLDICIARCLAAGISYSSNSGNLSTSQKSPSSANNGGLVLIGSSSATSSSVPSLSLTSSSSAGLSSPGSSSSSSSSSTSTSGSNSNRSSRPTSNNSNSNSNYSPNHDQLPAQLSSRIINTRNGAISGVIVQLDG----------------RHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLV---SNPAKYAAIVAHHVNCASDLP-----HAHLMKCLRE-KTLDQLLSVPIRPPEFGFAFGPSIDG------------------VVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSG---DVQYGIEADRRSRILKAYVRNTYTFHLN--EIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFT------RNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQER-SRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIPDLHKPGGDNVPAAHHQLHDDDDEDNNIPSDASVKPLNPPYISRAANAAAMAN--FTIFTNQVFSLLNLSSPSSSLQRNGTRYGGGKIYPDDMMDGDHAGGAASASQDSDGFAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLSEPRPQTKLKR----------------------------QENGQMPNNICGDLETLTIHAKSDPATILSHHHAMQHHQLPPPEFADIPHRAPPPPKHMKSLQDPGGGGSVSGAVGVS-GVVQMPPPHALQVMGNQCGTLTKKSCMKQTQAQAQQHSPAQQQQQQQQQQQQHVVTHQQHLQNHHN---------QSMTTVLTTAGGLVVPTPPTVPVIVASTTQHQQHQQQHQQQQHQQQQQQQQQQHPLMDELRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIC7-1", "uniprot_id": "Q9VIC7_DROME", "id": "Q9VIC7-1", "name": "", "aln": "MKFRLAAFWLFLLTVGGNHKLLSHVSPMGVAAEKQPLHKGNELENAMKLREAPKQSRVIGDITTTIQPDSDPGRSIGHQALRRAKAPPPSLELHFRQNLNKLFAGDETTHVGHTNATDNTTAAVLATDEGSSEHEPSTTHHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVT---------------SGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHK--HLSRLLPYLRTESEDCLYLNLYVPHEEPQ--------------------------------------STPKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSID--AHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASG--LFHRAILMSGSAMSDWAAS---NQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRH-RRYQDILHIPTALTQFSTSLGPIVDG------------------HVIPNQPYKVMGHYT----------------------------------------------EHFSRYDLLFGITESESYHTLAAL---ALEEGLRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPS------GNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQLQKPGQEVITGHMSKYGPRDHGAEDPVRTLKLLLQEPSLAGPTQSGESTETAAENMYNAPPTFGHVHKMQGGSDFEDLVTSTNSLESGEDHPQAPPETVAKSEATMQLLIALITIIIVLNLLIYGTFLLRQRRRRAKALPFPAPKLGGTILSYDGANDEELKRCSKSRDGDDSFVLEMTRKSNTYEAIKTGQRSLSCSTVDTHTKVCEWMSSQEAPKSGSFNTATPPPQPILSDGRLIICQDIEVADAALLIP-QHMHEPQHYEMLLQRQHSALTEPSDEILQQQYPLRNHSHSHSDPVDMILAADEQVTSFVHADDVDINVTSRDDSDGLEVIPLTSAQQLELLRQRNYPKVLPTEQDLINSSYKRNSLPPQNFNAPLPPPRTISNTLGRRRRDSSNITTSPLQVARDCGGEDEDLKEPQITQNTLIVGPIVPKSPASSLKRVKRMPESSAMTALSGSFQSFEAVPPAHETTPPQGGERTECIYAIRPSPGSCSWAAPNGDLYAQPMKSSSRNSLIPRPTKPAESQSQATPAGPAGESLGSTGMATASRIPQLQRQASGKDLQARTATDNTANPLGCQPRTDSTISSGSSASYASTTDSSSSSSTGTVRTELQQFQPAPGRSITTNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KT70-1", "uniprot_id": "Q7KT70_DROME", "id": "Q7KT70-1", "name": "", "aln": "----MMHKLKYRDKLKWLLALLVLIGTCFIQTRGQTRDPRFYSRPGVDYHWPNPGDPDYRTYTFNDRRYGHYQPNGYGANYPGRNPPGQYPQGMPNEDRFRFDPNDPNARTQFPGVLAGWREDLQGKQRRDS-----------------LTLERDVFVTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRGWQ-LLQAVDFGPACPQPVR-------------------YTGATKGIMDMDEDCLYLNVYSPKTGAG---------------------------------------VAQKYPVMVYIHGGEFIRGASNLFQGHILASFYDVVVVTLNYRLGALGFLSTGDE---NSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRN--IVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIES------SWKLVNCLRTGRSFYELGNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTQTPETLIRAG-----------------------------------------------KFNRNIQYMTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFR-YNYTLNPNGVYEAIKYIYTFWPD-PNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTTVEALNLPQWRKYPHDIERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNP---TPQQVLGMHFQRAYQGEIRYLNINTTYN--------SSILLNYRQTECAFWTQYLPTVIGVLVPTYPPTTEYWWEPKEPLQIAFWSMSVACFFLIVLV----------------------------VICCIMWRNAKRQSDRFYDEDVFIN----------------GEGLEPEQDTRGVDNAHMVTNHHALRSRDNIYEYR-------------------------------------------------------------------------DSPSTKTLASKAHTDTTSLRSPSSLAMTQKSSSQASLKSGISLKETNGHLVKQSERAATPRSQQNGSTAKVASPPVEEKRLLQPLSSTP----------------------------------VTQLQAEPAKRVPTAASVSGSSRSTTPVPSARSTTTHTTTATLSSQPAAQPRRTHLVEGVPQTSV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : *. : : : *:*** .* ** ** * : * : *.*** : : .*******:* * : .*::::** .: .:.* ::. :*::: :::*.*:*****.**** .. : .**.::* **:*: :** *.** . :*: * .:*.:.. *: : :..:.* **:.:: *: .. : : :. : * :.*** : :: . ** :* .: . : : *:. *. . : . : .: : . *. : ::* .* : : *:*.: .. . : :: *.*: :: : :* .* ::**.: *:* : : : : : . : :** ** : :* . .: :. * . : . . : . : . . ", "identical_positions": 89, "similar_positions": 154, "identity": "5.97%" }, { "cls_id": "homologset.agr.RGD:621119", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZ94-1", "uniprot_id": "NLGN3_HUMAN", "id": "Q9NZ94-1", "name": "Neuroligin-3", "aln": "----------------------------------------------------------------------------MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRAS--------------------------------------TQAPAPTVNTHFGKLRGARVPLPS-EILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTAN----LDIVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTG----DQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLT--LSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLD------TVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDD-------------PEILMEQGEFLN------------------------------------------YDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWAD-RDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP-----------------------------TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKAN-RFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYN--------LHDMFH----------YTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAG---------------------------------------------PLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAG-----------------APELGAAPEEELAALQLGPTHH-------------------ECEAGPPHDTLRLTALPDYTLT-----------------LRRSPDDIPLMTPNTITMIPNSLVG---------------------------------------------------------------------------LQTLHPYNTFAAGFNSTG-----------------------------------------LPHSHSTTRV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62889-1", "uniprot_id": "NLGN3_RAT", "id": "Q62889-1", "name": "Neuroligin-3", "aln": "----------------------------------------------------------------------------MWLQLGLPSLSLSPTPTVGRSLCLILWFLSLVLRAS--------------------------------------TQAPAPTVNTHFGKLRGARVPLPS-EILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTAN----LDIVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTG----DQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLT--LSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLD------TVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDD-------------PEILMEQGEFLN------------------------------------------YDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWAD-RDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP-----------------------------TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKAN-RFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYN--------LHDMFH----------YTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAPGSWNGDQDAG---------------------------------------------PLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGTG-----------------APELGTAPEEELAALQLGPTHH-------------------ECEAGPPHDTLRLTALPDYTLT-----------------LRRSPDDIPLMTPNTITMIPNSLVG---------------------------------------------------------------------------LQTLHPYNTFAAGFNSTG-----------------------------------------LPNSHSTTRV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYM5-1", "uniprot_id": "NLGN3_MOUSE", "id": "Q8BYM5-1", "name": "Neuroligin-3", "aln": "----------------------------------------------------------------------------MWLQ---PSLSLSPTPTVGRSLCLTLGFLSLVLRAS--------------------------------------TQAPAPTVNTHFGKLRGARVPLPS-EILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTAN----LDIVATYIQEPNEDCLYLNVYVPTED--------------------GSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTG----DQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLT--LSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLD------TVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDD-------------PEILMEQGEFLN------------------------------------------YDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWAD-RDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP-----------------------------TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKAN-RFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYN--------LHDMFH----------YTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAPGSWNGDQDAG---------------------------------------------PLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGTG-----------------APELGTAPEEELAALQLGPTHH-------------------ECEAGPPHDTLRLTALPDYTLT-----------------LRRSPDDIPLMTPNTITMIPNSLVG---------------------------------------------------------------------------LQTLHPYNTFAAGFNSTG-----------------------------------------LPHSHSTTRV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VIC6-1", "uniprot_id": "Q9VIC6_DROME", "id": "Q9VIC6-1", "name": "", "aln": "MVMLLSKRQLPPSAATRTRRKVPPTRRRSTWALSSLLALVVLDICIARCLAAGISYSSNSGNLSTSQKSPSSANNGGLVLIGSSSATSSSVPSLSLTSSSSAGLSSPGSSSSSSSSSTSTSGSNSNRSSRPTSNNSNSNSNYSPNHDQLPAQLSSRIINTRNGAISGVIVQLDG-RHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSS--SSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYS-KLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCAS----DLP-HAHLMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGG-------DYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFN-SGDVQYGIEADRRSRILKAYVRNTYTFHLN--EIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHR-----------------------------NSYLYVFDYQTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGS--RQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIPDLHKPGGDNVPAAHHQLHDDDDEDNNIPSDASVKPLNPPYISRAANAAAMANFTIFTNQVFSLLNLSSPSSSLQRNGTRYGGG-----KIYPDDMMD------GDHAGG--------AASASQD-------SDGFAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLSEPRPQTKLKRQ--------------------ENGQMPNNICGDLETLTIHA---------------------KSDPATILSHHHAMQHHQLP------------------PPEFADIPHRAPPPPKHMKSLQDP------------------------------GGGGSVSG--AVGVSG--------VVQMPPP---------------HALQVMGNQCGTLTKKS------------------------------CMKQTQ----AQAQQHSPAQQQQQQQQQQQQ-------HVVT--HQQHLQN---------------HHNQSMTTVLTTAGG-----LVVPTPP------TVPVIVASTTQHQQH--------------------------QQQHQQQQHQQQQQQQQQQHPLMDELRV-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A6H2EDS1-1", "uniprot_id": "A0A6H2EDS1_DROME", "id": "A0A6H2EDS1-1", "name": "", "aln": "--------------------------------------------------------------MGESQ----------LLLLLR---------LLLLPTVLISWMHCAGASTADIYKG---------------------------------ARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEK-----------------------------------------KLPVIVFIHGESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRG-LFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRH-HEQIVDCLRDVPLEDLYLADIQAPNFLTSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFS-AHDIQNGFEGERRDKIIRTYVRNAYNYHLN--EIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLRLIPELHRAGMEDVIARHNLFRNHDDMD---LYEGPVKP-DPFGISTAAGASGSSSSSSSSSRLLLVDEQLMMKKGRGLNGSAYLNGILGVTTVEPNNMYTTCIPIGGNYSSSGGVFAPTTLANASSDTLASGFEAAGYAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLEVKTLQKQYQQRSLHQQVPYPPEPIKHAHYHMGHSQSSANVIVDVESHQDQAGQAAMLLQAAAAAAAAAANDVKPPPPHICSNTGMQQQQQVGGGSGGALNNGGIEGSKVTTDNLGNVTYSTSSKQQQQHQQQQQQQQREHMQIKGMTGTQTFGRSGSGSGGGAGGGAGSASGGASVVVSGSSVSYNPGMMTLPKSGGLHHAATLNYARNTTALNMSGGGTALVDSRGNVLLTSTAVGPGMAGTGAGGGSSGGGGGGDCMTLPRNLGLAAAGRHNPTTELQQYQQQQQSSKHQSNGAVLTGMQSHHIRGPRPPLRTASSTTTNSSSNNSAMGVAVGVGGGVGNMLLDQTPSGGSSSSGVSSAPSSSKGHHTHSHSHAAHLVHSHGDGLVLTSASPVGGQQQQHPQQHQHPQQQQQVPQAAMDEMREFYAPKQPDDDGQLNGTPVDADAATQVVGAGRTGGMGAPPISASDHKQRQLKKLRFKREIHALALEGGDVARGYCSCDEQWTNSSSPTSTTTSATMSPTLPAGGSAGDAGRHATGNGPGNSSAGSSGIVKMAAAPGKRSERLKQQHHVRFSDEKNFSD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIC7-1", "uniprot_id": "Q9VIC7_DROME", "id": "Q9VIC7-1", "name": "", "aln": "MKFRLAAFWLFLLTVGGNHKLLSHVSPMGVAAEKQPLHKGNELENAMKLREAPKQSRVIGDITTTIQPDSDPGRSIGHQALRRAKAPPPSLELHFRQNLNKLFAGDETTHVGHTNATDNTTAAVLATDEGSSEHEPSTTHHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLS--PHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTP----------------------------------------KQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPS---IDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLM--VSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTSLGPIVDGHVIPNQ------------PYKVMGHYTEHFS-----------------------------------------RYDLLFGITESESYHTLA-ALALEEGLRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRR-----------------------------NYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKG-IFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQLQKPGQEVITGHMSKYGPRDHGAEDPVRTLKLLLQEPSLAGPTQSGESTETAAENMYNAPPTFGHVHKMQG------------------------GSDFEDLVTSTNSLESGEDHPQAPPETVAKSEATMQLLIALITIIIVLNLLIYGTFLLRQRRRRAKALPFPAPKLGGT-----------------ILSYDGANDEELKRCSKSRDGDD----------------SFVLEMTRKSNTYEAIKTGQRSLSCSTVDTHTKVCEWMSSQEAPKSGSFNTATPPPQPILSDGRLIICQDIEVADAALLIP----------------QHMHEPQHYEMLLQRQHSALTEPSDEILQQQYPLRNHSHSHSDPVDMILAADEQVTSFVHADDVDIN---------------------------------VTSRDDSDGLEVIPLTSAQQLELLRQRNYPKVLPTEQDLINSSYKRNSLPPQNFNAPLPPPRTISNTLGRRRRDSSNITTSPLQVARDCGGEDEDLKEPQITQNTLIVGPIVPKSPASSLKRVKRMPESSAMTALSGSFQSFEAVPPAHETTPPQGGERTECIYAIRPSPGSCSWAAPNGDLYAQPMKSSSRNSLIPRPTKPAESQSQATPAGPAGESLGSTGMATASRIPQLQRQASGKDLQARTATDNTANPLGCQPRTDSTISSGSSASYASTTDSSSSSSTGTVRTELQQFQPAPGRSITTNI----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::.: * : * : * *: : *:*** .* : ** *. .. *.*:: : : .*****.: :. *. : .::. .*******:: * : .*:*::** *: .:** ***:*:***:::*:*:***:*:**** .. .**.*:* : **:*:.:** **** :*: * . **:*: * : **:***: ***. : *: :. : :*. : * ::.***. .:: ..: ::** :** ** **:: *: .*. . : *. . : :: . : . *. : ::* : * * : : : *:*.* :: . *:::.::**.*:. . *:: : ** .** :*:**.:**:*: . : * :: : **.:. * : ::* : :* . :*. . :. : * : . . * .: :.: **: ::.**:* :. . :: : * . . : . : . . : . .. :. . : . . . .. ", "identical_positions": 133, "similar_positions": 198, "identity": "8.31%" }, { "cls_id": "homologset.agr.RGD:621120", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30285-1", "uniprot_id": "CDK4_MOUSE", "id": "P30285-1", "name": "Cyclin-dependent kinase 4", "aln": "-------MAATR---YEPVAEIG-VGAYGTVYKARD----PHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEAFEHPNVVRLMDVCATS-RTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPVETIKDLMRQFLSGLDFLHANCIVHRDLKPENILVTSNG-----TVKLADFGLARIYSYQMALTPV--------VVTLWYRAPEVLLQS-TYATPVDMWSVGCIFAEMFRRKP----------------LFCGNSEADQLGKIFDLIGLPPEDDWPREVSLP-----RGAFAPRG---------------------PRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKEESDAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35426-1", "uniprot_id": "CDK4_RAT", "id": "P35426-1", "name": "Cyclin-dependent kinase 4", "aln": "-------MATTR---YEPVAEIG-VGAYGTVYKARD----PHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEAFEHPNVVRLMDVCATS-RTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPVETIKDLMRQFLSGLDFLHANCIVHRDLKPENILVTSNG-----TVKLADFGLARIYSYQMALTPV--------VVTLWYRAPEVLLQS-TYATPVDMWSVGCIFAEMFRRKP----------------LFCGNSEADQLGKIFDLIGLPPEDDWPREVSLP-----RGAFSPRG---------------------PRPVQSVVPEMEESGAQLLLEMLTFNPLKRISAFRALQHSYLHKEESDPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11802-1", "uniprot_id": "CDK4_HUMAN", "id": "P11802-1", "name": "Cyclin-dependent kinase 4", "aln": "-------MATSR---YEPVAEIG-VGAYGTVYKARD----PHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATS-RTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGG-----TVKLADFGLARIYSYQMALTPV--------VVTLWYRAPEVLLQS-TYATPVDMWSVGCIFAEMFRRKP----------------LFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLP-----RGAFPPRG---------------------PRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NC60-1", "uniprot_id": "A0A8M1NC60_DANRE", "id": "A0A8M1NC60-1", "name": "Cyclin-dependent kinase 4", "aln": "-------MAQEVGLQYEPVAEIG-GGAYGTVYKARD----RDSGQFVALKSVRVQTNQ---DGLPLSTVREVALLKRLEQFDHPNIVRLMDVCATL-RTDQETKVTLVFEHVDQDLRTYLEKVPAPGLPVDKIRDLMQQLLCGLAFLHTNRVLHRDLKPENILVTSRG-----QVKLADFGLARIYSCHMALTPV--------VVTLWYRSPEVLLQS-TYATPVDIWSTGCIFAEMFRRKP----------------LFCGDSEADQLGKIFAVIGLPAEDQWPTDVTLS-----HHNFSPQS---------------------PRPITDCVPDITEKGAELLLKMLTFDPLKRISALNALDHPFFSE------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43568-1", "uniprot_id": "CAK1_YEAST", "id": "P43568-1", "name": "Serine/threonine-protein kinase CAK1", "aln": "MKLDSIDITHCQLVKSTRTARIYRSDTYAIKCLALDFDIPPHNAKFEVSILNKLGNKCKHILPLLESKATDNNDLLLLFPFEEMNLYEFMQMHYKRDRRKKNPYYDLLNPSIPIVADPPVQKYTNQLDVNRYSLSFFRQMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLIIISQWFQRETSRMGHVPAMIDDGSDDMNSDGSDFRLICSIFEKLGIPSIQKWEEVAQHGSVDAFVGMFGADGDGKYVLDQEKDVQISIVERNMPRLDEIADVKVKQKFINCILGMVSFSPNERWSCQRILQELEKP-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .*.* .:*. * * ...:* . :: . * *.. : * * *:. *: .:*:: . * .:: *: : . ::* . .:::*:: *: *** * ::***:**:**::*. : : ***:: : : :. : * *::****: * **:** *::: *:*:. : ...*: : .** :*:*. :.* . * . . ** .: :. : :* *::*.* :* *. . *:. ", "identical_positions": 63, "similar_positions": 97, "identity": "16.8%" }, { "cls_id": "homologset.agr.RGD:621121", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64261-1", "uniprot_id": "CDK6_MOUSE", "id": "Q64261-1", "name": "Cyclin-dependent kinase 6", "aln": "MEKDSLSRADQQYECVAEIG----EGAYGKVFKARDLKNGGR----FVALKRVRVQTSEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIK----DMMFQLLRGLDFLHSHRVVHRDLKPQNILVTS-----SGQIKLADFGLARIYS--------FQMALTSVVVTLWYRAPEVLLQS-SYATPVDLWSVGCIFAEMFRRKP---------LFRGSSDVDQLG-------KILDIIGLPGEEDWPRDVALP-RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYFQDLERYKDNLNSHLPSNQSTSELNTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MA87-1", "uniprot_id": "F1MA87_RAT", "id": "F1MA87-1", "name": "cyclin-dependent kinase", "aln": "MEKDSLSRADQQYECVAEIG----EGAYGKVFKARDLKNGGR----FVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIK----DMMFQLLRGLDFLHSHRVVHRDLKPQNILVTS-----SGQIKLADFGLARIYS--------FQMALTSVVVTLWYRAPEVLLQS-SYATPVDLWSVGCIFAELFRRKP---------LFRGSSDVDQLG-------KILDVIGLPGEEDWPRDVALP-RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYFQDLERYKDNLHSHLSSSQSTSELNTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00534-1", "uniprot_id": "CDK6_HUMAN", "id": "Q00534-1", "name": "Cyclin-dependent kinase 6", "aln": "MEKDGLCRADQQYECVAEIG----EGAYGKVFKARDLKNGGR----FVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIK----DMMFQLLRGLDFLHSHRVVHRDLKPQNILVTS-----SGQIKLADFGLARIYS--------FQMALTSVVVTLWYRAPEVLLQS-SYATPVDLWSVGCIFAEMFRRKP---------LFRGSSDVDQLG-------KILDVIGLPGEEDWPRDVALP-RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P43568-1", "uniprot_id": "CAK1_YEAST", "id": "P43568-1", "name": "Serine/threonine-protein kinase CAK1", "aln": "MKLDSIDITHCQLVKSTRTARIYRSDTYAIKCLALDFDIPPHNAKFEVSILNKLGNKCKHILPLLESKATDNNDLLLLFPFEEMN-LYEFMQMHYKRDRRKKNPYYDLLNPSIPIVADPPVQKYTNQLDVNRYSLSFFRQMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLIIISQWFQRETSRMGHVPAMIDDGSDDMNSDGSDFRLICSIFEKLGIPSIQKWEEVAQHGSVDAFVGMFGADGDGKYVLDQEKDVQISIVERNMPRLDEIADVKVKQKFINCILGMVSFSPNERWSCQRILQELEKP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *.: :. * :. . ..:*. * *:. : *:: . :. :. :** : . * * . :: *::. : . . * . :: :: .:. * : . :: .:: *::.*: ***.::::***:*****::*. * :: : ***:: : : .: : * *:*****: .* **:**: *::: *:*:. : **.*::. * .*:: :*:*. :.* . . :** . . : . :* . :: : .: ..*: . .: * . . ..: . .: .**:..", "identical_positions": 62, "similar_positions": 128, "identity": "16.8%" }, { "cls_id": "homologset.agr.RGD:621122", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2BIG8-1", "uniprot_id": "A0A8M2BIG8_DANRE", "id": "A0A8M2BIG8-1", "name": "", "aln": "MGLTQSSGDGPEGGTEGYHVHGVQEDSPAER--AGLEPFFDFIISIGHNRLNQENDMLKDLLKANVEKPVKMEVYSTKTMRMRELEVVPSNMWGGQGLLGASVRFCSFQGANENVWHVLDVESNSPAALAGLQEHSDFIVGADQVLQDSEDFFSLIEAHEGKPLKLLIYNTETDKCREVIVTPNGAWGGEGSLGCGIGYGYLHRIPAQPEGPKSEKVSSRESPVAGNPEQEYPTNGFSEVSLM--ASGQSLSGMDLETPLPPPIQRVMDPGFSDHSEVALMNSEVSDIADRLDLSTSSIDMTNTSLAVKEDADVSGVEELQDSDFHSGDPEEQITEEYSAVDFSSSITPPSNASPPLSLSHSLLPNPTLENSVPTDVASLMNSSIPPLDSSIPALDISSLLIDPAALHLESSALPEEHFPSETDGVS---QGFSEKPQSFEGQEEPVSSDLTSFDSHNADVEAEAALQ------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1RRZ2-1", "uniprot_id": "A0A8M1RRZ2_DANRE", "id": "A0A8M1RRZ2-1", "name": "", "aln": "MGLIQS-VFATQG---GYHVHGVQENSPAER--AGLEPFFDFILSIGHTRLNKESSTLKELLKANVEKPVKLQVYSSKVMRVRELELVPSNLWGGQGLLGASVRFCSFTGADQYVWHVLDVEVNSPAELAGLKPYSDYIIGADQVLQESEDFFSLIEACEGKSLKLLVYNTHTDRCREVLITPNAAWGGNGSLGCDVGFGYLHRIPMCP------VTSDQHQNTPEHQENKHR----SELFLV--NSTDAEEKTDAQG------GSVQDT--SEDSAQCEISPALA-LSECLDSSTSLLDASTSSLKADDD-----------------DEEE------------SAISSPK-----------------------------ISSSVLLEDSGICESQTSPAIINTTPKHDQTVKCTQKTLA------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q91X51-1", "uniprot_id": "GORS1_MOUSE", "id": "Q91X51-1", "name": "Golgi reassembly-stacking protein 1", "aln": "MGLGAS-SEQPAGG-EGFHLHGVQENSPAQQ--AGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMKVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPAALAGLCPYTDYIVGSDQILQESEDFFTLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQP------SSQHKKPPGATPPGTPATTSQLTAFPLG--APPPWPIPQDSSGP----ELGSRQSDFMEALPQVPGSFMEGQLLGPGSPSHGAADCGGCLRAMEIPLQ------------PPPPVQRVMDPGFLDVSGMSLLDSSNISVCPSLSSSTVLTSTAVSVSGPEDIGSSSSSHERGGEATWSGSEFEISFPDSPGAQAQADHLPRLTLPDGLTSAASPEEGLSAELLEAQT-EEPADTASLDCRAETEGRASQAQATPDPEPGL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35254-1", "uniprot_id": "GORS1_RAT", "id": "O35254-1", "name": "Golgi reassembly-stacking protein 1", "aln": "MGLGAS-SEQPAGG-EGFHLHGVQENSPAQQ--AGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMRVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPAALAGLRPYTDYIVGSDQILQESEDFFTLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQP------SSQYKKPPSASSPGTPAKTPQPNAFPLG--APPPWPIPQDSSGP----ELGSRQSDYMEALPQVPGGFMEEQLPGPGSPGHGTADYGGCLHSMEIPLQ------------PPPPVQRVMDPGFLDVSGMSLLDSNNTSVCPSLSSSSLLTPTAVSALGPEDIGSSSSSHERGGEATWSGSEFEISFPDSPGSQAQVDHLPRLTLPDGLTSAASPEEGLSAELLEAQT-EEPAHTASLDCMAQTEGPAGQVQAAPDPEPGLCEGPW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BQQ3-1", "uniprot_id": "GORS1_HUMAN", "id": "Q9BQQ3-1", "name": "Golgi reassembly-stacking protein 1", "aln": "MGLGVS-AEQPAGGAEGFHLHGVQENSPAQQ--AGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMRVREVEVVPSNMWGGQGLLGASVRFCSFRRASEQVWHVLDVEPSSPAALAGLRPYTDYVVGSDQILQESEDFFTLIESHEGKPLKLMVYNSKSDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQP------PSYHKKPPGTPPP----SALPLGAPPPD--ALPPGPTPEDSPSL----ETGSRQSDYMEALLQAPGSSMEDPLPGPGSPSHSAPDPDGLPHFMETPLQ------------PPPPVQRVMDPGFLDVSGISLLDNSNASVWPSLPSSTELTTTAVSTSGPEDICSSSSSHERGGEATWSGSEFEVSFLDSPGAQAQADHLPQLTLPDSLTSAASPEDGLSAELLEAQAEEEPASTEGLDTGTEAEGLDSQAQISTTE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VW57-1", "uniprot_id": "Q9VW57_DROME", "id": "Q9VW57-1", "name": "", "aln": "MGSSHS-IHVPGGGTEGYHVLKVQDNSPGQK--AGLEAFFDFIVAIAGTRLDQDNDMLKELLRQNVDKPVRLTVYSSKTQTVRELTLTPSNNWGGQGLLGVSIRFCSFEGANESVWHILEVHPNSPAELAGLRAYSDYVIGADAIRHENDDLFTLIETHEQQPLKMYVYNLDDDACREVTIKPNTAWGGEGALGCGIGFGYLHRIPVQAEP---VTSSSAAVPAAAAAESTAPLLTAGGAAPAGAQVAQVVSPTLPYIPPLANTFGSTNAEVRPPTIEPPAQSLFKTYFNPDEATDALTAALESQATIAEPVSVPAP--------PAVADVSVAQPQVQVPAPAQPLPPPANIFIPGVFDPSTQQNANALGGIPAAQLPFPQATAAPAAVPMFSAPQQAYMSAPAALSYPAGAQTVPSYPQVQPSMGGLFPTQPTPLPPQMAHVFAPPVPPQAGAAPAAGNDELSGPAVNQAGN------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04410-1", "uniprot_id": "GRH1_YEAST", "id": "Q04410-1", "name": "GRASP65 homolog protein 1", "aln": "-------MFRIAKNLVRTFEQSVQDTLALSQDSSNLDAFFQSIPPN--------------LLSAQLESPVDAVSEGVKHTNVNETLSGLRIVWVDEMQFQLQSFFDYIVGFNDDPVPVVSNQHG--------FSYPDYRR-----------ITSIFNEHCGRTLKVNIWSAKGGTFRDEYIS---IISKESDDLDDVSLNHDERRPSSG------EAHQFQALGFKVQWTPLIASTFTYHILN-VNIPDGPAQSAGLIP-----DEDYIIGCQDGLLATGGETLLQDIVRSRANYDLVLYVYNKVSDCVRPIT-----------------VHIGPDGRLG--------------------------CNVGYGFLHRIPTVKHCPQQAQQQGQDDNPVPVPVPVESETAFVPSAFTAPPVPTKKKSKNKKGTQPLAMDDYFNEGRDKSSTAAKSAESDILAPPPQKQSSSD----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **: . .: :.*:.:*: * . ** :::.** . * :.* * .: : . * : .: ::. . . :.*: : :::: :.**: ::. . . *: :. . :. .:. .: .* * . . . . . ", "identical_positions": 19, "similar_positions": 64, "identity": "3.96%" }, { "cls_id": "homologset.agr.RGD:621123", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70289-1", "uniprot_id": "PTPRV_MOUSE", "id": "P70289-1", "name": "Receptor-type tyrosine-protein phosphatase V", "aln": "MRPLILLAALLWLQDSLAQEDVCSSLDGSPDRQGGGPPLSVSVTSRGRPTSLFLSWVAAEPGGFDYALCLRAMNLSGFPEGQQLQAHTNESSFEFHGLVPGSRYQLELTVLRPCWQNVTITLTARTAPTVVRGLQLHSTGSPASLEASWSDASGDQDSYQLLLYHPESHTLACNVSVSPDTLSYNFGDLLPGSQYVLEVITWAGSLHAKTSILQWTEPVPPDHLRVRALGTSSLQAFWNSSEGATWFHLILTDLLEGTNLTKVVRQGISTHTFLRLSPGTPYQLKICAAAGPHQIWGPNATEWTYPSYPSDLVLTPLWNELWASWKAGQGARDGYVLKLSGPVENTTTLGPEECNAVFPGPLPPGHYTLGLRVLAGPYDAWVEGSIWLAESAARPMEVPGARLWLEGLEATKQPGRRALLYSVDAPGLLGNISVSSGATHVTFCGLVPGAHYRVDIASSMGDITQSLTGYTSPLPPQSLEIISRNSPSDLTIGWAPAPGQMEGYKVTWHQDGSQRSPGDLVDLGPDISSLTLKSLVPGSCYTVSAWAWSGNLSSDSQKIHSCTRPAPPTNLSLGFAHQPATLRASWCHPPGGRDAFQLRLYRLRPLTLESEKILSQEAQNFSWAQLPAGYEFQVQLSTLWGSEESGSANTTGWTPPSAPTLVNVTSEAPTQLHVSWVHAAGDRSSYQVTLYQESTRTATSIVGPKADSTSFWGLTPGTKYKVEAISWAGPLYTAAANVSAWTYPLTPNELLASMQAGSAVVNLAWPSGPLGRGTCHAQLSDAGHLSWEQPLSLGQDLLMLRNLIPGHTVSLSVKCRAGPLQASTHPLVLSVEPGPVEDVFCQPEATYLSLNWTMPTGDVAVCLVEVEQLVPGGSAHFVFQVNTSEDALLLPNLTPTTSYRLSLTV-LGGNRQWSRAVTLVCTTSAEVWHPPELAEAPQVELGTGMGVTVTRGMFGKDDGQIQWYGIIATINMTLAQPSQEAINHTWYDHYYRGHDSYLALLFPNPFYPEPWAVPRSWTVPVGTEDCDNTQEICNGHLKPGFQYRFSIAAFSRLSSPETILAFSAFSEPQASISLVAMPLTVMMGTVVGCIIIVCAVLCLLCRRGLKGPRSEKNGFSQELMPYNLWRTHRPIPSHSFRQSYEAKSARAHQAFFQEFEELKEVGKDQPRLEAEHPANITKNRYPHVLPYDHSRVRLTQLSGEPHSDYINANFIPGYSHPQEIIATQGPLKKTVEDFWRLVWEQQVHVIIMLTVGMENGRVLCEHYWPVNSTPVTHGHITTHLLAEESEDEWTRREFQLQHGAEQKQRRVKQLQFTTWPDHSVPEAPSSLLAFV--------ELVQEEVKATQGKGPILVHCSAGVGRTGTFVALLPAVRQLEEEQVVDVFNTVYILRLHRPLMIQTLSQYIFLHSCLLNKILEGPSDASDSGPIPVMNFAQACAKRAANANAGFLKEYRLLKQAIKDETGSLLPSPDYNQNSIASCHHSQEQLALVEESPADNMLAASLFPGGPSGRDHVVLTGSAGPKELWEMVWEHGAYVLVSLGLPDTKEKPQDIWPMEMQPIVTDMVTVHRVAESN-TAGWPSTLIRVIHGDSGTERQVQCLQFPHCETGSELPANTLLTFLDAVGQCCSRGNSKKPGTLLSHSSKVTNQLSTFLAMEQLLQQAGTERTVDVFSVALKQTQACAVKTPTLEQYIYLYNCLNSALRNRLPRARK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64612-1", "uniprot_id": "PTPRV_RAT", "id": "Q64612-1", "name": "Receptor-type tyrosine-protein phosphatase V", "aln": "MRPLILLAALLWLQGFLAEDDACSSLEGSPDRQGGGPLLSVNVSSHGKSTSLFLSWVAAELGGFDYALSLRSVNSSGSPEGQQLQAHTNESGFEFHGLVPGSRYQLKLTVLRPCWQNVTITLTARTAPTVVRGLQLHSAGSPARLEASWSDAPGDQDSYQLLLYHLESQTLACNVSVSPDTLSYSFGDLLPGTQYVLEVITWAGSLHAKTSILQWTEPVPPDHLALRALGTSSLQAFWNSSEGATSFHLMLTDLLGGTNTTAVIRQGVSTHTFLHLSPGTPHELKICASAGPHQIWGPSATEWTYPSYPSDLVLTPLRNELWASWKAGLGARDGYVLKLSGPMESTSTLGPEECNAVFPGPLPPGHYTLQLKVLAGPYDAWVEGSTWLAESAALPREVPGARLWLDGLEASKQPGRRALLYSDDAPGSLGNISVPSGATHVIFCGLVPGAHYRVDIASSTGDISQSISGYTSPLPPQSLEVISRSSPSDLTIAWGPAPGQLEGYKVTWHQDGSQRSPGDLVDLGPDTLSLTLKSLVPGSCYTVSAWAWAGNLDSDSQKIHSCTRPAPPTNLSLGFAHQPAALKASWYHPPGGRDAFHLRLYRLRPLTLESEKVLPREAQNFSWAQLTAGCEFQVQLSTLWGSERSSSANATGWTPPSAPTLVNVTSDAPTQLQVSWAHVPGGRSRYQVTLYQESTRTATSIMGPKEDGTSFLGLTPGTKYKVEVISWAGPLYTAAANVSAWTYPLIPNELLVSMQAGSAVVNLAWPSGPLGQGACHAQLSDAGHLSWEQPLKLGQELFMLRDLTPGHTISMSVRCRAGPLQASTHLVVLSVEPGPVEDVLCHPEATYLALNWTMPAGDVDVCLVVVERLVPGGGTHFVFQVNTSGDALLLPNLMPTTSYRLSLTV-LGRNSRWSRAVSLVCSTSAEAWHPPELAEPPQVELGTGMGVTVMRGMFGKDDGQIQWYGIIATINMTLAQPSREAINYTWYDHYYRGCESFLALLFPNPFYPEPWAGPRSWTVPVGTEDCDNTQEICNGRLKSGFQYRFSVVAFSRLNTPETILAFSAFSEPRASISLAIIPLTVMLGAVVGSIVIVCAVLCLLRWRCLKGPRSEKDGFSKELMPYNLWRTHRPIPIHSFRQSYEAKSAHAHQTFFQEFEELKEVGKDQPRLEAEHPDNIIKNRYPHVLPYDHSRVRLTQLPGEPHSDYINANFIPGYSHTQEIIATQGPLKKTLEDFWRLVWEQQVHVIIMLTVGMENGRVLCEHYWPANSTPVTHGHITIHLLAEEPEDEWTRREFQLQHGTEQKQRRVKQLQFTTWPDHSVPEAPSSLLAFV--------ELVQEQVQATQGKGPILVHCSAGVGRTGTFVALLRLLRQLEEEKVADVFNTVYILRLHRPLMIQTLSQYIFLHSCLLNKILEGPPDSSDSGPISVMDFAQACAKRAANANAGFLKEYKLLKQAIKDGTGSLLPPPDYNQNSIVSRRHSQEQFALVEECPEDSMLEASLFPGGPSGCDHVVLTGSAGPKELWEMVWEHDAHVLVSLGLPDTKEKPPDIWPVEMQPIVTDMVTVHRVSESNTTTGWPSTLFRVIHGESGKERQVQCLQFPCSESGCELPANTLLTFLDAVGQCCFRGKSKKPGTLLSHSSKNTNQLGTFLAMEQLLQQAGTERTVDVFNVALKQSQACGLMTPTLEQYIYLYNCLNSALLNGLPRAGKWPAPC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25044-1", "uniprot_id": "PTP1_YEAST", "id": "P25044-1", "name": "Tyrosine-protein phosphatase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAPWYIRQRDTDLLG---KFKFIQNQEDGRLREATNG--------------------------------------------------------TVNSRWSLG------------------------------------------------------------VSIEP-------------------------------------------------RNDARNRYVNIMPYERNRVHLKT-LSGNDYINASYVKVNVP----------------------GQSIEPGYYIATQG-----------------PTRKTWDQFWQMCYHN------------------------------------------------------------------------------------CPLDNIVIVMVTPLVEYNREKCYQYWP--------RGGVDDTVRIASKWESPG------------------------------------------------------------GANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTP-------------------------------------------TDPLVG-----------------------------PVKTVHHFYFDLWKDMNKPEE---VVPIM--------ELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDT-------------------------------------------------------LDFKNITERSRHSDRATEEYTRDLIEQIVLQLR-----------SQRMKMVQTKDQFLFIY----------------------------------------HAAKYLNSLSVNQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40048-1", "uniprot_id": "PTP3_YEAST", "id": "P40048-1", "name": "Tyrosine-protein phosphatase 3", "aln": "--------------------------------------------------------------------------MKDSVDCPSILPTDRTSVLSETSTLVGSSSHVYSRHAPMNSYHNSMNSNIYHSPKASSPLVSYKTSSPVLLKRATAPVLPSFKPKEQRYNKPQGCSLITAVELG------KIIETLPDEKVLLLDVRPFTEHAKSIITNSIHVCLPSTLLRRKNFTFSKLLDNLTPSEQSVLKSKLAIDNLRIIIYDSTANQTESSVSLPCYG-----------------------------------------------------------------------IASKLIEFDTNVKKTVSILMCGFPQFKILFPDHINTNTFNSDCISSAEPKSPKTNLMNSLHNTAPHMTATTPLSSPQMNLKLKVPDDSRSDHSNFSSSPSPRNVLSDSPMSSSSPISALFKFQLPAPQTNINQMFKFSQNEEIMGLETYLSAVN-----------------------------------------IKEEHERWYNNDSAKKSLQNFQFPKNQNSLEKDTNKDKLGFQIRYENLSKNYEKEVIDSVIPEWFQHLMSIPKIELVSQFQKLDFLEKRRLNHSVSFRKKENSFILEKPSSYPEQLTSTSSSTIMPPKFPDVNKVQKRSHSQPIFTQYSKYKSMLSLESD----------------------------------------------------SDSESDDVIISSG-----------------------------------------------------------------------------------------------------------------VELGAKNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYINAN-------------YLSLPRFSVEQNSSFQTTTTTTRRVRYIATQAPMPSTVHDFYTCILN--------------------------------------------------------------------------------------NGVPLVLSLTNDFENGIEKCYRYWQ-----EGNYNGIHVKLLEKKILKMPSTTSMRKN---------------------------------------------------TMGTQNSSLYSAGVQGNSSNYSTDNDNDNDNNNNNNN-------------------------------------------NSNIAVTAAACDDDDDDDDDAILIRKILLTYHDQEKPYELLQIQVKNWPDLGTLLNPISILQAINVKNHIIDTLFARNYYQNDQLPTILVHCSAGCGRTGTLCTIDSILSNF------------------------------------------------------------EMFEMLQKEFVKLKYPAKLFDPISWTIN--------IFRKQRISMVQNINQFIFIY----------------------------------------DCLLFYFRLRLDDITERTD--------------------------------------GDGSNKDNISLSALIEQIEKLEILQTFVDDKLKELPQ-------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . .: . : . * :: * *: *. * . . : :: .. .. : : . : : . * .*. : . . . : .. : : * . : . . :. : :: . * * . :: : * .. .. .*:****** *****: :: : : . . . *:. .. . :. :*: :: . * : : ", "identical_positions": 27, "similar_positions": 80, "identity": "1.57%" }, { "cls_id": "homologset.agr.RGD:621124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51952-1", "uniprot_id": "CDK7_RAT", "id": "P51952-1", "name": "Cyclin-dependent kinase 7", "aln": "--------ANRNEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNWAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIP---LQHIFIAAGDDLLELIQGLFLFNPCTRITASQALRTKYFSNRPGPTPGCQLPRPNCPVEALKEQSNPAM-----ATKRKRAEALEQ------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q03147-1", "uniprot_id": "CDK7_MOUSE", "id": "Q03147-1", "name": "Cyclin-dependent kinase 7", "aln": "MAVDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGVP---LQHIFIAAGDDLLELIQGLFLFNPCTRTTASQALKTKYFSNRPGPTPGCQLPRPNCPVEALKEPANPTV-----ATKRKRAEALEQG---ILPKKLIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50613-1", "uniprot_id": "CDK7_HUMAN", "id": "P50613-1", "name": "Cyclin-dependent kinase 7", "aln": "MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIP---LHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPAL-----AIKRKRTEALEQG---GLPKKLIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24216-1", "uniprot_id": "Q24216_DROME", "id": "Q24216-1", "name": "Cyclin-dependent kinase 7", "aln": "MLPNANDKTERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENIIGLVDVFGQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLHLNWILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHDYLQFRNFPGTP---LDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPTVGPKLPMP-SAILAAKEGANPQTGDTKPALKRKLVETTVRGNGLAQKKRLQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06242-1", "uniprot_id": "KIN28_YEAST", "id": "P06242-1", "name": "Serine/threonine-protein kinase KIN28", "aln": "MKVN-----MEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKT---SEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPP-------------------SDPSS------IKIRN------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . :*** :*.** . : *.: :*:*:** .: :**:: :*:**:* ***:.* *:* *:* * .*:.**::*: *****:***:.:::* :.***: :***:*: : * ::************.. :* :*:.*****::: :*: * :*******:*******: * .:*:*:** *:***:**:*::**:.*:**: * :*****: :**.:..: * :: :* . * : * **.: :.:: :: :** * :. :.* ** : * * ::* * : ", "identical_positions": 124, "similar_positions": 102, "identity": "34.73%" }, { "cls_id": "homologset.agr.RGD:621125", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64380-1", "uniprot_id": "SARDH_RAT", "id": "Q64380-1", "name": "Sarcosine dehydrogenase, mitochondrial", "aln": "MASLSRVLRVAATCPRGRSARNLGLQPLAREARPTTEKSVPYQCTLKEEAQGASVVPQGPSQPLPSTANVVVIGGGSLGCQTLYHLAKLGVGGVVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTRQVVSHDLEEETGLHTGWIQNGGLFIASNQQRLDEYKRLMSLGKAYGIESHVLSPAETKDLYPLMNVDDLYGTLYVPRDGTMDPAGTCTTLTRAAVARGAQVIENCAVTGIRVRTDDFGVRRVTAVETQHGSIQTPCVVNCAGVWASSVGRMAGVKVPLVAMHHAYVVTERIEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWDEVSDKFAFGLFDLDWDVFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIVHGRPEKDMYSYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAGRNMRRDPLHEELLGQGCVFQERQGWERPGWFNPQET--AQVLDYDYYGAYGHQAHKDYAYSRLLGDEYTFD-FPPHHCVIQKECLACRTAAAVFNMSYFGKFYLLGADARKAPDWLFSADVNRPPGSTVYTCMLNQRGGTESDLTVSCLAPGAQASPLAPAFEGDGYYLAVGGAVAQHNWSHINTVLQDQEFRCQLMDCSEDLGMLSIQGPASRDILQDVLDADLSNEAFPFSTHQLVRAAGHLVRAIRLSFVGELGWELHVPQASCLPVYRAVMAAGAKHGLVNAGYRAIDSLSIEKGYRHWHADLRSDDSPLEAGLAFTCKLKTSVPFLGREALEKQRATGLRRRLVCLTVEEEVPMFGLEAIWRNGQVVGHVRRADFGFTVNKTIAYGYIRDPSGGPVSLDFVKNGDYALERMGVTYAAQVHLKSPFDPDNKRVKGIY--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LB7-1", "uniprot_id": "SARDH_MOUSE", "id": "Q99LB7-1", "name": "Sarcosine dehydrogenase, mitochondrial", "aln": "MASLSRVLRVAATCPRGRAAWNLGLQPLATEARPTTEKSVPYQRTLKEEAQGASVVPQGPSQPLPSTANVVVIGGGSLGCQTLYHLAKLGVGGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTRQVVSRDLEEETGLHTGWIQNGGLFIASNQQRLNEYKRLMSLGKAYGIESHVLSPAETKSLYPLMNVDDLYGTLYVPQDGTMDPAGTCTTLTRAAVARGAQVIENCAVTGIRVRTDDFGVRRVAAVETEHGSIQTPCVVNCAGVWASKVGRMAGVKVPLVAMHHAYVVTERIEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWDVFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIVHGRPEKDMYSYDIRRFHHSLTDHTRWIRERSHESYAKNYSVVFPHDEPLAGRNMRRDPLHEELLGQGCVFQERQGWERPGWFNPQET--AQVLDYDYYGAYGNQAHKDYTYSRLLGDEYTFD-FPPHHHMIQKECLACRGAAAVFNMSYFGKFYLLGVDARKAADWLFSADVNRPPGSTVYTCMLNQRGGTESDLTVSRLAPGTQASPLVPAFEGDCYYLAVGGAVAQHNWSHINTVLQDQEFRCQLMDSSEDLGMLSIQGPASRDILQDVLDADLSNEAFPFSTHQLVRAAGHLVRAIRLSFVGELGWELHVPRASCLPVYRAVMAAGARHGLVNAGYRAIDSLSIEKGYRHWHADLRPDDSPLEAGLAFTCKLKTSVPFLGREALEKQRATGLRRRLICLTVEEEVPMFGLEAIWRNGQVVGHVRRADFGFTVNKTIAYGYIRDPSGGPVSLDFVKNGEYALERMGVTYAAQVHLKSPFDPDNKRVKGIY--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UL12-1", "uniprot_id": "SARDH_HUMAN", "id": "Q9UL12-1", "name": "Sarcosine dehydrogenase, mitochondrial", "aln": "MASLSRALRVAAAHPRQSPTRGMGPCNLSSAAGPTAEKSVPYQRTLKE-GQGTSVVAQGPSRPLPSTANVVVIGGGSLGCQTLYHLAKLGMSGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVRRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAGVKVPLVAMHHAYVVTERIEGIQNMPNVRDHDASVYLRLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELAHWIIHGRPEKDMHGYDIRRFHHSLTDHPRWIRERSHESYAKNYSVVFPHDEPLAGRNMRRDPLHEELLGQGCVFQERHGWERPGWFHPRGP--APVLEYDYYGAYGSRAHEDYAYRRLLADEYTFA-FPPHHDTIKKECLACRGAAAVFDMSYFGKFYLVGLDARKAADWLFSADVSRPPGSTVYTCMLNHRGGTESDLTVSRLAPSHQASPLAPAFEGDGYYLAMGGAVAQHNWSHITTVLQDQKSQCQLIDSSEDLGMISIQGPASRAILQEVLDADLSNEAFPFSTHKLLRAAGHLVRAMRLSFVGELGWELHIPKASCVPVYRAVMAAGAKHGLINAGYRAIDSLSIEKGYRHWHADLRPDDSPLEAGLAFTCKLKSPVPFLGREALEQQRAAGLRRRLVCFTMEDKVPMFGLEAIWRNGQVVGHVRRADFGFAIDKTIAYGYIHDPSGGPVSLDFVKSGDYALERMGVTYGAQAHLKSPFDPNNKRVKGIY--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZAZ2-1", "uniprot_id": "A1ZAZ2_DROME", "id": "A1ZAZ2-1", "name": "", "aln": "-MWRHRILQQASRR---------GISKQVREDGGARRE---------------------PSGFLPGAADVVVIGGGSAGCHTLYHLARRGVK-AVLLERAQLTAGTTWHTAGLLWRLRPNDVDIQLLANSRRML-QQLEEETELDPGWIQNGGIFIAHNETRLDEYRRLATVGSALGIENQVLSPEDTQKLFPLLDPSAFVGALYSPGDGVMDPAMLCAALKKAATNLGAQVIENCGVDDLLLEQTARGKK-VVGVSTPFGDIKAEKVVNATGVWGRDLVARHGTHLPLVPMKHAYIVSESIPGVRGLPNIRDHDYSTYFRIQGDAICMGGYEPNPILLEPVPKDFHFGLYELDWSVFETHVEGAQKLCPSYAKYGVKSTVCGPESFTPDHKPLMGPDPNLDGLYHNCGFNSAGMMFGGGCGEQTALWVIQGQPDLPMFGFDLRRFTQEQGKAIQWIREKSHESYVKNYSMVFKYDQPLAGRDFQKDPLHDEMMKAGAVMEEKQGWERPGFFLPTGSKKAVVQPYDWYGSYVHQRHKDSEYERVLDGDLHYSRFSEYHDLIGSEALACRNNAVVFNMSYFAKLLLDGPQAQEAADWLFSANTNRDPSKTVYTCALNDAGGVEADVTISRLAPGSGE-VYNPKINGQGFYIVAGGASAFYTYSVLLAEIRRKGFNASLKDLTAELGVISIQGPNSRKILQPLIDCDLSDEHVAPNSTRLAKFGDVGLRLLRVSFVGELGYELHVPKKDCAAVYRSLMKAGAGEDLRNAGYRSLYSLSSEKGYHLWSFDLRPDDTPLEAGLGFTCR-KTGADYRGKAAIENQRAEGLKKRLVYLTLRDQVPIWGLEGVYRNGEPVGILRRAEYAYTLGKSLGQTYVSRPDGKIIDADYIRNGEYEVDILGKKYRADCHLRSPFDPTGQRVLGNYASESKSNK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: *: * : .: ** **.:*:******** **:******: *: .***** :**:***********:***.**:::***::*::: ::***** *..*******:*** *. **:**:** ::*.* *:*.:**** :*: *:**:: . : *:** * **.**** *::* :** ******** * .: : * : *..*.* .*.*:: ***.:***. : *.::***.*:***:*:* * *::.:**:**** *.*:*:****:.:****.***: : *...* ***::***.** *:*** : * * *:******************* *:* *:: .*********:*****:: * *:::*:*: *..:*:*** :. . :****:*****.****:** :*:*****::::****:*:: *.*::*::******:* * . * * **:**:* : *:* * *:* .: : *. :* * .*.**** *.**:****.*: * * :*::*.******:..* *..***** **. **.*:*:*:* ***. * ::*: :*:. *** * :.:* : : :: : ...* * : :**::***** ** *** ::*.***:* .. .: :* : .. :* :*:*******:***:*: .* .***::* *** ..* *****:: *** ****: * ***.**:******.***: *: . : *: *:*:*** **::**: :*:.::**::***.::***: ** :***::.:::.*::. *: *.* :. *:::.*:* :: :* .* *: **:***** .:** * * ", "identical_positions": 433, "similar_positions": 265, "identity": "46.56%" }, { "cls_id": "homologset.agr.RGD:621126", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R5K6-1", "uniprot_id": "TOB1_RAT", "id": "Q8R5K6-1", "name": "Protein Tob1", "aln": "MQLEIQVALNFIISYLYNKLPRRRVNIFGEELERLLKQKYEGHWYPEKPYKGSGFRCIHVGEKVDPVIEQASKESGLDIDDVRGNLPQDLSVWIDPFEVSYQIGEKGPVKVLYVD--DSNENGCELDKEIKNSFNPEAQVFMPI---------------------SDPASSVSSSPS--------------------------------------------PPFGHSA-AVSPTFMPR-STQPLTFTTATFAATKFGSTKMKNSGR---SSKVARTSPISLGLNVNVNDLLKQK--------AISSSMHSLYG---------------LGLGSQQQPQPQPQQPPS----QPP----PPPPPP---------------------------------------------------QQQQQHQQQQQQQQQQQQQP---------------QQQTSALSPNAKEFIFPNMQGQGSSTNG----------------MFPGDSPLNLS--PLQYSNAFNVFAAYGGLNEKSFVDGLN--FSLNNIQYSN---------QQFQPVMAN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50616-1", "uniprot_id": "TOB1_HUMAN", "id": "P50616-1", "name": "Protein Tob1", "aln": "MQLEIQVALNFIISYLYNKLPRRRVNIFGEELERLLKKKYEGHWYPEKPYKGSGFRCIHIGEKVDPVIEQASKESGLDIDDVRGNLPQDLSVWIDPFEVSYQIGEKGPVKVLYVD--DNNENGCELDKEIKNSFNPEAQVFMPI---------------------SDPASSVSSSPS--------------------------------------------PPFGHSA-AVSPTFMPR-STQPLTFTTATFAATKFGSTKMKNSGR---SNKVARTSPINLGL--NVNDLLKQK--------AISSSMHSLYG---------------LGLGSQQQPQQ--QQQPA----QPP----PPPPPP---------------------------------------------------QQQQ-------------------------------QQKTSALSPNAKEFIFPNMQGQGSSTNG----------------MFPGDSPLNLS--PLQYSNAFDVFAAYGGLNEKSFVDGLN--FSLNNMQYSN---------QQFQPVMAN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61471-1", "uniprot_id": "TOB1_MOUSE", "id": "Q61471-1", "name": "Protein Tob1", "aln": "MQLEIQVALNFIISYLYNKLPRRRVNIFGEELERLLKKKYEGHWYPEKPYKGSGFRCIHVGEKVDPVIEQASKESGLDIDDVRGNLPQDLSVWIDPFEVSYQIGEKGPVKVLYVD--DSSETGCELDKEIKNSFNPEAQVFMPI---------------------SDPASSVSSSPS--------------------------------------------PPFGHSA-AVSPTFMPR-STQPLTFTTATFAATKFGSTKMKNSGR---SSKVARTSPINLGLTVNVNDLLKQK--------AISSSVHSLYG---------------LGLGSQQQPQPQPQQQQQ----QQPSSSQPPPPLP---------------------------------------------------QQQQQQPQQQQQQ----------------------QQQTSALSPNAKEFIFPNMQGQGSSTNG----------------MFPGDSPLNLS--PLQYSNAFDVFAAYGGLNEKSFVDGLN--FSLNNMQYSN---------QQFQPVMAN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VXJ9-1", "uniprot_id": "Q9VXJ9_DROME", "id": "Q9VXJ9-1", "name": "", "aln": "MHIEIQVALNFVISYLYNKLPRRRVNIFGEELEKALRDKFQDHWYPEKPFKGSAYRCLKTGDPIDSVLERAARESGVPIGDILENLPNELSVWIDPGEVSFRIGEKGAVKILYTENNENHEDSHSADREVTKMFNPEAQCFRPIDAVNTTMNNMSLSPKGHHQSGSSPHSAASSSPTYKGSPNRTISGSCSSVSGAGSGTGSGSRSGSNHAPGPGTAPGPVPGNGATANAAAAAFMQRGAQAPLTFTTATFAQTKFGSTKLKTSSKRTNSSSAYRMSPTEFSNYIKQRAMQQQMHHGHAVVPSAGSSVSAAYGGMDAVSPARSLSPNPLSLAGNQNQSVSGSSADSYYYPNMPINMYPQYGNPRCLFESHFSADVSSMGLYVSGTAGAAVTAVGSVGANKYSTYLEPCYYGNGHANTQQHSQQQTRVGMDRPNSSESCFGLNVDCGSVVLEDSSSSSSAAAAAVAVTIAGDSSAENSPLSTPTLAAVNVGKATSPPTNSTNNSSSHPIQQQEQPSSSSGNGNGNANANANGNNGNNSNSNTKLIDGISSFYGTGSSYQQLLVAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::********:*********************: *:.*::.*******:***.:**:: *: :*.*:*:*::***: *.*: ***::******* ***::*****.**:**.: :. * . . *:*:.: ****** * ** *.* *:.****: * * :* *.:.:** * : ********** *******:*.*.: *... * ** .:. : . : :* : .**: : ** *.*..:*: . .. : * * * : * :.:*: *. * : .: *:.*: *. * :*. * * *:* .: . :. *. * :: .:* * * .* : : ..:* ::. ", "identical_positions": 156, "similar_positions": 112, "identity": "27.66%" }, { "cls_id": "homologset.agr.RGD:621127", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55096-1", "uniprot_id": "DPP3_RAT", "id": "O55096-1", "name": "Dipeptidyl peptidase 3", "aln": "---------------------------------------------------------------MADT--QYILPNDIGVSSLDCR-EAFRLLSPTERLYAHHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSKAAQQ----------------HPEEVRSLWQTCGELMFSLEPRLRHLGLGKEGVTTYFSG--DCAMEDAKLAQDFLDSQNLSAYNTRLFKVVGQEGKYHYEVRLASVLNTEPALDSELTSKLKSYEFQGNHFQVTRGDYAPILQKVVEHLEKAKAYAANSHQEQMLAQYVESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKDMSAKFERLVASAEQLLKELPWPPAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAY-ATKREKLTFMEEEDKDLYIRWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLNPQVLQIFGFEG-TDAEDVIYVNWLNMVRAGL-LALEFYTPETANWRQAHMQARFVILRVLLEAGEGLVTVTPTTGSDGRPDARVHLDRSKIRSVGKPALERFLRRLQVLKSTGDVVAGRALYEGYAAVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLE-GSEVQLVEYEASAAGLIRSFCERFPEDGPELEEVLTQLATADAQFWRDQVQEAPSGQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KK7-1", "uniprot_id": "DPP3_MOUSE", "id": "Q99KK7-1", "name": "Dipeptidyl peptidase 3", "aln": "---------------------------------------------------------------MADT--QYILPNDIGVSSLDCR-EAFRLLSPTERLYAHHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKDKLGRVILGSKAAQQ----------------RPEEVRDLWQTCGDLMFSLEPRLRHLGLGKEGVTTYFSG--DCTMEDAKLAQDFLDSQNLSAYNTRLFKVVGQEGKSHYEVRLASVLNTDPALDSELTSKLKRYEFQGNHFQVTRGDYAPILQKVVEHLEKAKAYAANSHQEQMLAQYVESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKAMSAKFERLVASAEQLLKELPWPLAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAY-AAKREKLTFLEEEDKDLYIRWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDKETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLNPQVLEIFGFEG-ADAEDVIYVNWLNMVRAGL-LALEFYTPEAANWRQAHMQARFVILRVLLEAGEGLVTVTPTTGSDGRPDARVRLDRSKIRSVGRPALERFLRRLQVLKSTGDVVAGRALYEGYAAVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLE-GSEVQLVEYEASAAGLIRSFCERFPEDGPELEEVLIQLAAADARFWRNQAQEAPPGQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NY33-1", "uniprot_id": "DPP3_HUMAN", "id": "Q9NY33-1", "name": "Dipeptidyl peptidase 3", "aln": "---------------------------------------------------------------MADT--QYILPNDIGVSSLDCR-EAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQ----------------HPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSG--NCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAY-ATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEG-ADAEDVIYVNWLNMVRAGL-LALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLE-GSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWK-GPSEAPSGQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHR8-1", "uniprot_id": "DPP3_DROME", "id": "Q9VHR8-1", "name": "Dipeptidyl peptidase 3", "aln": "MFWLRGLQRSRQQLNRLCHFRSRLNYGTSPSIRSVQPSISRSLGFCSSLVRYSCSTNLPQPAEMASKTAHFVLPNTQPIADLDCK-SAFENLTEKEKLYAHHFSQASWDGGLIALIQSSPEAPLIFSLLHRIFLAEKIPVLRAKALEAGVSADDFTAFLVYACGVFANAGNYKGMGDSKIVPNLSEKQFETIVKASAAYSD----------------EPR-VGKIFEKVKNLIYALESRNEILGFAPDGITTYWSD--NCTKEDSEIVNAWLTSKRIEPYMCRTFKIVEN-GQTVYDVKLGSVAES-----TQDGITLPLEEYNGNKFRVTRGDYQKLLQRVNQHLLQAQKYAANENESKMIEHYVRSFEQGSLDEHKNGSRWWIKDKGPVIETYIGFIETYRDPAGGRAEFEGFVAMVNKESSAKFSELVNRAEKLIEYLPWTEPYEKDSYLKPDFTSLDVLTFAGSGVPAGINIPNYDEIRQDEGFKNVSLGNVLAN---INRKDPIPFLTEEDQTLMKEYKVKAFEVQVGLHELLGHGSGKLFRIDENGVYNFDKENTKNLVTGEPITKWYLPGETYDTKFGAIGSSYEECRAEAVGLYLSLQRDILEIFGFKDKAEQDNIIYVNWLSLIWNGMGVALEMFNPKSKLWLQAHSRARFVIMKVLLEAGEGLVKVEETE--KGK-NLLLTVDRSKIDTVGRKALGDFLTKLQVYKSTADIEAASKMYEHYSKVDESGSHPWAKWRDICLAHKKPRMILVQANTAIGQDQKVQLKTYEPTHEGYIQSWVERYPN--TDIDDLLESIVEKDKKYFPTAFNN------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08225-1", "uniprot_id": "DPP3_YEAST", "id": "Q08225-1", "name": "Probable dipeptidyl peptidase 3", "aln": "-------------------------------------------------------------------MSHFFADHDAPLSMLSVKTEYFPQLTDKEQKYAHFMSKASHAGSRVVMRQVSHESEPIFDLILAIHSKLN----GKYPEDDITQKQQTGLYLEYVSQFLSNLGNFKSFGDTKFIPRCEVKFFKQLLELAKINPCSSPLTLSPVDVNHEFTSHHLFSTINELIDIGIYHVEEKAALLGFPSQGYTSAYYLGLPVTPEDMALLKEQLFAELAILPEN---TRINKVGENSFQIWVASENVKNQITETYPSGQITLSN-AVTKVEFIFGDHSREMRLVASYLKEAQKFAANDTQKAMLQEYINHFVTGSSQAHKEAQKLWVKDISPVIETNIGFIETYREPSGIIGEFESLVAIQNKERTAKFSSLVNNAEEFISLLPWSKDYEKPIFNPPDFTSLEVLTFTGSGIPAGINIPNYDDVRLKIGFKNVSLGNILSAAAKSSSKHPPSFISQEDRPIFEKYQSDSFEVQVGIHELLGHGSGKLLTEFTDG-FNFDKENPPLGLDGKPVSTYYKVGETWGSKFGQLAGPFEECRAEVIAMFLLTNKKILDIFGFHDVESQDKVIYAGYLQMARAGL-LALEYWNPKTGKWGQPHMQARFSIMKTFMKHSTDKNFLKLEMN-STNDDFAIKLDKSLIKTAGHECVKDYLKHLHVYKCSGDVEQGSKYFIDRSTVTP----DLASLRDIVLSKRLPRRQFIQSNSYIDDNNKVTLKEYDETPQGMLQSFLDREL---------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : :: *. : . * *: .*: **:.:*:*: *. .: * * *: *: *: :. . . :: :* *.. . :* **:*.:**:*::*. . : :: : . . : : :: :* : **: :* *: : : ** : : * :: . : *: ::: :.* . : : : . ... **: :: * . * :*: :***. : *: .*:. * ** : **...: *::* .*::*: *****:**:* * .***.:**: ** :***. ** **:::. ***. :** : ******:****:***:**********::* *********:*: :. .*: ::*: : :: :*:****:***********: .* :***:*. *: : .:* ***:.:**. :...:****** :.::* : .:*:****.. . :.:**..:*.: *: :*** :.*:: * *.* :*** *::.::: . . : . . : : :*:* * :.*: .: :* :*:* *.:.*: . : : * . ** * :: .* ::*.*: : ...* * *: : * ::*: :* ", "identical_positions": 194, "similar_positions": 231, "identity": "23.49%" }, { "cls_id": "homologset.agr.RGD:621129", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUQ3-1", "uniprot_id": "OLIG1_RAT", "id": "Q9WUQ3-1", "name": "Oligodendrocyte transcription factor 1", "aln": "MYYAVSQARVNAAPATMLRPQRPGDVQLGASLYELVGYRQPPISSSSST-------SSSSTASLLPKPAREKPEAPLAEPRGPAPES-----GGARADAKEEQQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHC------------QGAP--GRKLSKIATLLLARNYILLLGSSLQELRRALGD-----GAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPETLRPTKYLSLALDEPPCGQFALPAGGAGSPGLCSCAVCKFPHLVPAGLGLAAVQAQFSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JKN5-1", "uniprot_id": "OLIG1_MOUSE", "id": "Q9JKN5-1", "name": "Oligodendrocyte transcription factor 1", "aln": "MYYAISQARVNAAPATMLRPQRPGDVQLGASLYELVGYRQPPISSSSS--------SSSSTASLLPKPAREKAEAPLAEPRGPAPES-----GGARADAKEEQQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHC------------QGAP--GRKLSKIATLLLARNYILLLGSSLQELRRALGD-----GAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPETLRPTKYLSLALDEPPCGQFSLPAGGAGSPGLCSCAVCKFPHLVPAGLGLAAVQAQFSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAK6-1", "uniprot_id": "OLIG1_HUMAN", "id": "Q8TAK6-1", "name": "Oligodendrocyte transcription factor 1", "aln": "MYYAVSQARVNAVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAP-AEPPGPGPGSGAHPGGSARPDAKEEQQQQ-LRRKINSRERKRMQDLNLAMDALREVILPYSAAHC------------QGAP--GRKLSKIATLLLARNYILLLGSSLQELRRALGE-----GAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGAGGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WIQ7-1", "uniprot_id": "A8WIQ7_DANRE", "id": "A8WIQ7-1", "name": "", "aln": "---------MQAVSGVRYREQ-------GESSLQQLMPRMVRVTGSGG---------PGSNVGSLQGPLRS------SKPP--------------RELSSEE--QQELRRKINSRERKRMQDLNVAMDALREVMVPYSSSPTGVGGALQHPYLPPGAPTTGRRLSKISTLVLARNYILLLGSSLQEMRRLLGEVSIGMGVSGTVPRLLLTGGWPFLTGPGQLLLSP----PEQQLGVAKCPLLPQGAQEE-PLAWGPGSMSESPVCQCGVCRTPRVVHVNP-----AMRFPK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*.... * * * * : : * :.*.. ..:.. * . *. ::* * :.** ** *****************:********::***:: *** **:****:**:***************:** **: *.. :.*****:* : :.**.:**:* * : * :* *. . :: *. . . :* *.**: *::* .. :*.*", "identical_positions": 98, "similar_positions": 62, "identity": "33.56%" }, { "cls_id": "homologset.agr.RGD:621130", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43237-1", "uniprot_id": "DC1L2_HUMAN", "id": "O43237-1", "name": "Cytoplasmic dynein 1 light intermediate chain 2", "aln": "MAP-VGVEKKLLLGPNGPAVAAAGDLTSEEEEGQSLWSSILSEVSTRARSKLPSGKNILVFGEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHDEDRDDHTRCNVWILDGDLYHKGLLKFAVSAESLPETLVIFVADMSRPWTVMESLQKWASVLREHIDKMKIPPEKMRELERKFVKDFQDYMEPEEGCQ-GSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVVCTKCDAVSVLEKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTTPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDK--ELAAEDEQVFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPAS---VPSSSPGTSVKKPDPNIK-NNAASEGVLASFFNSLLSKKTGSPGSPGAGGVQSTAKKS-------------------GQKTVLSNVQEELDRMTRKPDSMVTNSSTENEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PDL0-1", "uniprot_id": "DC1L2_MOUSE", "id": "Q6PDL0-1", "name": "Cytoplasmic dynein 1 light intermediate chain 2", "aln": "MAP-VGVEKKLLLGPNGPAVAAAGDLTSEEEEGQSLWSSILSEVSTRARSKLPSGKNILVFGEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHDEDRDDHTRCNVWILDGDLYHKGLLKFAVSAESLRETLVIFVADMSRPWTIMESLQKWASVLREHIDKMKIPPEEMRDLERKFMKEFQDYIEPEEGCQ-GSPQRRGPLTSGSDEDSVALPLGDNVLTHNLGIPVLVVCTKCDAMSVLEKEHDYRDEHLDFIQAHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTIPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDK--ELAAEDEQVFLMKQQSLLAKQPATPTRTSESPARGPSGSPRTQGRGGPAS---VPSASPGTSVKKPDPNIK-NNAASEGVLASFFNSLLSKKTGSPGSPSAGGVQSTAKKS-------------------GQKTVLSNVQEELDRMTRKPDSMVTNSSTENEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62698-1", "uniprot_id": "DC1L2_RAT", "id": "Q62698-1", "name": "Cytoplasmic dynein 1 light intermediate chain 2", "aln": "MAP-VGVEKKLLLGPNGPAVAAAGDLTSEEEEGQSLWSSILSEVSTRARSKLPSGKNILVFGEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHDEDRDDHTRCNVWILDGDLYHKGLLKFAVSAESLRETLVIFVADMSRPWTIMESLQKWASVLREHIDKMKIPPEEMRDLERKFMKDFQDYIEPEEGCQ-GSPQRRGPLTSGSDEDNVALPLGDNVLTHNLGIPVLVVCTKCDAVSILEKEHDYRDEHLDFIQAHLRGFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTIPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDK--ELAAEDEQVFLMKQQ--------------ESPARGPSGSPRTQGRGGPAS---VPSASPGTSVKKPDPNIK-NNAASEGVLASFFNSLLSKKTGSPGSPSAGGVQSTAKKSGTEGEPQSFRSLTEQCCQTGQKTVLSNVQEELDRMTRKPDSMVTNSSTENEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VZ20-1", "uniprot_id": "Q9VZ20_DROME", "id": "Q9VZ20-1", "name": "Dynein light intermediate chain", "aln": "MAMNSGTQTNALTSS---FTMKKKDAAAEKE---NLWSAILNEVQTQGSTKLPSNKSVLVLGDNATGKTTLIAKLQGVEDPKKGSGLEYAYIDVKDEYRDDMTRLGVWVLDGDPGHTNLLHYALNETNYAHTLVILTVSMTQPWGWLEQLNHWIKVLGQHIDSLQLDAKEKEAARQRLTTTWQSYCEVGDDLDPGSPVKR-TMRNNSIDEDDLLPLTEDALITNLGLDIVVVVTKTDYMTTLEKEYEYRDEHFDFIQQWIRNFCLRHGTSLFYTSVKEDKNCDVLYKYLTHRIYGLPFRTPALVVEKDAVLIPAGWDSLKKISILYENMHGVKAENPYTDIIKSPPTRKAVSNREAEVQTEDEQAFLARQQEILKQ---------GDQVRGES-PLRSQGVGSNKSGPRTPGTTGQSSPKKIDPKLTPATPGAEGVLANFFNSLLHKKSGSPGTGGPGGAGNPAGPGRTANG-------TDAVMTPEKLAVRTDAAAELDRLSRSVKKEIDMSQSEC--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *.:.: * .. . * ::*:* .***:**.**.*:. :****.*.:**:*::.:*****::****.*. *** **** *:.*:** *** ** .**:**** *..**::*:. . .****:...*::** :*.*::* .** :***.::: .:: . .::: . :*.* * :. : *** :* .: ..* ::. *** ::.* ***: ::** ** * :: ****::*****:**** :* ***::*::*:******:** *:****:.*: **: * **********:******. ***:**:**: **.*:.* *:* .**.** * :: *: :****.** :** . .** * . *:** *. * .*.:: :* ** **::. ...:*****.****** **:****: ..**. ..* . : :* ::. ****::*. .. : *.:* ", "identical_positions": 215, "similar_positions": 159, "identity": "41.43%" }, { "cls_id": "homologset.agr.RGD:621132", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2NKI2-1", "uniprot_id": "VAX1_MOUSE", "id": "Q2NKI2-1", "name": "Ventral anterior homeobox 1", "aln": "MFGKPDKMDVRCHSDTEAARVSKNAHKESREIKGAEGSLPAAFLKEPQGAFSGSGASEDCNKSKSNSSADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAAAAAATAPGPAGAASQHQPAVGGAPGPGPAGPGGLHAGAPTASHGLFSLPVPSLLGSVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGAEKKALD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JM00-1", "uniprot_id": "VAX1_RAT", "id": "Q9JM00-1", "name": "Ventral anterior homeobox 1", "aln": "MFGKTDKMDVRCHSDTEAARVSKNAHKESREIKGAEGSLPAAFLKEPQGAFSASGASEDCNKSKSNSSADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAG--SAAAAAAAATAPGPAGAASQHPPAVGGAPGPGPAGPGGLHAGAPTASHGLFSLPVPSLLGSVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGAEKKALD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SQQ9-1", "uniprot_id": "VAX1_HUMAN", "id": "Q5SQQ9-1", "name": "Ventral anterior homeobox 1", "aln": "MFGKPDKMDVRCHSDAEAARVSKNAHKESRESKGAEGNLPAAFLKEPQGAFSASGAAEDCNKSKSNSAADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAG----SAAAAAAAAPGPAGAASPHPPAVGGAPGPGPAGPGGLHAGAPAAGHSLFSLPVPSLLGSVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGAEKKALD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q801E0-1", "uniprot_id": "VAX1_DANRE", "id": "Q801E0-1", "name": "Ventral anterior homeobox 1", "aln": "-------MEVRYSQDSESGMLLKNGLKEGKEGKDSQGSISKTFLKDQQESFSPSGAVENCEKSRASS-GDPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLTPPGLPGLLPHCGSSSLGSALRGPSLGITANGGSSS-----SSRSSAGSSGTAGGSPPLPTVTSSGTVTG-------LQGSPPA-HGLFSFPMPSLLGSVASRISSTPLGMAGSLAGNLQELSARYLCSSAFEPYSRTNGKEALDKKVLE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:** .*:*:. : **. **.:* *.::*.:. :***: * :** *** *:*:**::.* .***********************************************************************************************************************:*****.*** *.:.:********** . *.::. :: ::* :.*.**.:. ....... .* *:*.* *.***:*:**********:**:** *****************.***********.**. :**.*:", "identical_positions": 225, "similar_positions": 66, "identity": "66.57%" }, { "cls_id": "homologset.agr.RGD:621133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLZ9-1", "uniprot_id": "VAX2_RAT", "id": "Q9JLZ9-1", "name": "Ventral anterior homeobox 2", "aln": "MGDGGAERDRGPKRREEPGGRSGCRGEHRGAEDLRADTGSTSPRE----IAGTSASSPAGSRESGGDSDGQQALGETDHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSAFEAFATSNVLRLLEQGRLLSVPRAPSLLALSPGLPG----LTAGHRGTSLGDPRNSSQR----------LNPMPSASASSPLPPPLPAVCFSAAPLL----DLPASYKLGSSAFEPYSRLEQQKVGSPGQSDKKADI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTP9-1", "uniprot_id": "VAX2_MOUSE", "id": "Q9WTP9-1", "name": "Ventral anterior homeobox 2", "aln": "MGDGGAERDRGPKRREEPGGRSGRHGEHRGAEDLRADTGSASPRE----IAGTSASSPAGSRESGGDSDGQQALGETDHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATSNVLRLLEQGRLLSVPRAPSLLALTPGLPG----LPASHRGTSLVDPRNSSPR----------LNPMPSASASSPLPPPLPAICFSSAPLL----DLPAGYKLGSSAFEPYSRLEQQKVGSPGQSDKKADI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UIW0-1", "uniprot_id": "VAX2_HUMAN", "id": "Q9UIW0-1", "name": "Ventral anterior homeobox 2", "aln": "MGDGGAERDRGPARRAESGGGGGRCGDRSGAGDLRADGGGHSPTE----VAGTSASSPAGSRESGADSDGQPGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATSNILRLLEQGRLLSVPRAPSLLALTPSLPG----LPASHRGTSLGDPRNSSPR----------LNPLSSASASPPLPPPLPAVCFSSAPLL----DLPAGYELGSSAFEPYSWLER-KVGS-ASSCKKANT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q801E1-1", "uniprot_id": "VAX2_DANRE", "id": "Q801E1-1", "name": "Ventral anterior homeobox 2", "aln": "MFDQATSMGDGIAEDRNHCGSNSLCRDRGRESKSRTEVGNRSPVQSSTDTPGTSASTPTSSSEDGHD---KLLGVDPDYCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLELEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQTKDTDKR-SSSTSESLATCNILRLLEQGRLLSVPAPPPNPLLAHPHPGNGSLLGSPSVSTSSGVSSSTTPPGAGSGTFGLSLSSLSGTPPSPRLGVPPPSLCFTMPLLSGAHHELPSGYGCGTSAFEPYMRIER-KDGELGGKKTVS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .:. . * . : * .. :: . *:: *. ** : .*****:*:.* *.* * : :.*:*******************************************:******************************************::* :** ***: *::**.*:************* .*. *: ** * : .** . .:: *..:..:..*. * * *::**: . * :**:.* *:****** :*: * *. . . . : ", "identical_positions": 155, "similar_positions": 66, "identity": "49.36%" }, { "cls_id": "homologset.agr.RGD:621134", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62796-1", "uniprot_id": "RBP1_RAT", "id": "Q62796-1", "name": "RalA-binding protein 1", "aln": "------MTECFLPPTSSPSEHRRAEHGSGLTRTPSSEEISPTKFPELYRTGEPSPPHDILHEPPDIVSDDEKDHGKKKGKFKKKEKRTEGYVAFQEDSSGDEAESPSKMKRSKGIHVFKKPSFSKKKEKDFKIKEKPKEEKHKEEKHKEEKHKEKKCKDFTAADVVKQWKEKKKKKKPTQEPEVPQTDAPSLR--PIFGAPFADAVERTMMYDGIRLPAVFRECVDYMEKHGMKCEGIYRVSGIKSKVDELKAAYD-REESPNLEEYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTEVEKVQEFQRLLRELPEYNHLLLSWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVLFTHVQELFGTVLLKQVTRPLRWSNMATMPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGIKDFSKEERLWEVQRILTALKRKLREAKRQECETKIAQEIASLSKEDVSKEETNENEEVINILLAQENEILTEQEELLAMEQFLRRQIASEKEEIDRLRAEIAEIQSRQ-HGRSETEEYSSDSESESEDEEELQIILEDLQRQNEELEIKNNHLNQAVHEEREAIVELRVQLRLLQMLRAKSEQQLQEEEEPERRGGTGPLPCEGVLEVRAAKEQ-------AKPSPSKDRKETPI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62172-1", "uniprot_id": "RBP1_MOUSE", "id": "Q62172-1", "name": "RalA-binding protein 1", "aln": "------MTECFLPPSSSPSEHRRAEHGSGLTRTPSSEEISPTKFPGLYRTGEPSPPHDVLHEPPDTVSDDDKDHGKKKGKFKKKEKRTEGYAAFQEDSSGDEAESPSKVKRSKGIHVFKKPSFSKKKEKDFKIKEKPKEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQEPEVPQMDAPSVK--PIFGVPLVDAVERTMMYDGVRLPAVFRECVDYMEKHGMKCEGVYRVSGIKSKVDELKAAYD-REESPNLEEYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGKTTEMEKVQEFQRLLRELPECNHLLLSWLIVHLDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVLFTHVQELFGTVVLKQVTRPLRWSNMATMPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGIKDLSKEERLWEVQRILTALKRKLREAKRQECETKIAQEIASLSKEDVSKEEMNENEEVINILLAQENEILTEQEELLAMEQFLRRQIASEKEEIDRLRAEIAEIQSRQQHGRSETEEYSSDSESESEDEEELQLILEDLQRQNEELEIKNNHLNQAVHEEREAIIELRVQLRLLQMQRAKSEQQPQEEEEPERRGGIGPPPCDGVLEVRVAKEQ-------AKASPSKDRKETPI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15311-1", "uniprot_id": "RBP1_HUMAN", "id": "Q15311-1", "name": "RalA-binding protein 1", "aln": "------MTECFLPPTSSPSEHRRVEHGSGLTRTPSSEEISPTKFPGLYRTGEPSPPHDILHEPPDVVSDDEKDHGKKKGKFKKKEKRTEGYAAFQEDSSGDEAESPSKMKRSKGIHVFKKPSFSKKKEKDFKIKEKPKEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQEPEVPQIDVPNLK--PIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYD-REESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVFFTHVQELFGNVVLKQVMKPLRWSNMATMPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGIKDLSKEERLWEVQRILTALKRKLREAKRQECETKIAQEIASLSKEDVSKEEMNENEEVINILLAQENEILTEQEELLAMEQFLRRQIASEKEEIERLRAEIAEIQSRQQHGRSETEEYSSESESESEDEEELQIILEDLQRQNEELEIKNNHLNQAIHEEREAIIELRVQLRLLQMQRAKAEQQAQEDEEPEWRGGAVQPPRDGVLEPKAAKEQPKAGKEPAKPSPSRDRKETSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDG2-1", "uniprot_id": "RLIP_DROME", "id": "Q9VDG2-1", "name": "RalA-binding protein 1", "aln": "MDFDSPEEKEFPGLYASEAADAKSRKSKEESDFSEDHDHSKKDLLIGRRKDKKEKGKDRGYAALEGESSPEEELDTKSPSKSKKSKTFK----FTSSKSKEKREKSRDKSEKDSKHAEEEPSVSHKVKEKERDKEKDRDEPKKKDKEEKRKEKDKKAD-------KKDKKDKKSKQLSQQQDDVSAAEEVLALGYPVFGVSVSLATERSRCHDGVDIPLVVRDCIDFLQDH-LKCEQIYKIEPIKTRLMHFKRLYNNREHDSAVDELNLPTACSLLKLFLRELPEPLLTTDLVARFEEVASHPKVTTQQAELQQLLEQLPKCNRTLLAWVLLHFDAVIQQERHNKLNAQSLAMLLSPTLQMSHRLMVALLCHCNNLFADVQLIKYVPPLTS----TSPKLPDTPEDIQTELRKQDSLLSQIHSEMNAGFITKKREEQLWEVQRIITQLKRKLRTFEKKQEKTAEEVDNSSSAPPAVASEDTTDSKPAGTPAVSTNNSISQEE----PKTDTLTPKDAPNDFTIDPSTGFILLPKSNPHRENLLRLQIEYDELMEWQNELKARIVAE----RNEVYRLKQLYEQQSINSQMASLASG---------SQAPPESDYERIIEHYTRENALLEHKKNMLGMELKEERR------ACIALQVELRLQQF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :* : . : .:.. : ....: * ..: *..: . :* : . : *. ::: ..*. . .**.* : * ...* :: *.. . ..... *. ::**.*:* ::. : *** ::* :*::*.::.*.*:**.. *: *:**.*: . *: :*. : *:** .. *.**: :**: :* *.*:*:*:::.: :*** :*::. **::: .:* *: **... ::: : *..**** :**:*** ***.:*:.****...:.. : *:*:**.:**: * *::*:::*:* ** :* ..*:* *.::::****:*:*:*:: .:: * ::**. * * : ** * *.**:* .*: *:*:*: **. :* :::.*: .:**:*******:* ****** :::: :* : :* : *:.*: .:.: . . :: :*.* *: . : * : *.:. *: . * :*. : . : . :. * ::* : ::: * :** .:*: : :*:::.: :: . :* .*.: :. * * . ..:* . :*: * : . : : :", "identical_positions": 162, "similar_positions": 256, "identity": "24.4%" }, { "cls_id": "homologset.agr.RGD:621135", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63737-1", "uniprot_id": "PHLP_RAT", "id": "Q63737-1", "name": "Phosducin-like protein", "aln": "MTTLDDKLLGEKLQYYYSTSEDEDSDHEDKD------RGRGAPASSSTPAEAELAG---EGISVNTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMSCRSHLDEEEEQQKQKDLQEKISGKMTLKECGMMDKNLDDEEFLQQYRKQRMDEMRQQLHKGPQFKQVLEIPSGEGFLDMIDKEQKSTLIMVHIYEDGVPGTEAMNGCMICLAAEYPTVKFCRVRSSVIGASSRFTRNALPALLIYKAGELIGNFVRVTDQLGEDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBX2-1", "uniprot_id": "PHLP_MOUSE", "id": "Q9DBX2-1", "name": "Phosducin-like protein", "aln": "MTTLDDKLLGEKLQYYYSTSEDEDSDHEDKD------RGRGAPAISSTPAEAELAG---EGISINTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMSCRSHLDEEEEQQKQKDLQEKISGKMTLKEFGTKDKNLDDEEFLQQYRKQRMEEMRQQFHKGPQFKQVFEIPSGEGFLDMIDKEQKSTLIMVHIYEDGVPGTEAMNGCMICLATEYPAVKFCRVRSSVIGASSRFTRNALPALLIYKAGELIGNFVRVTDQLGEDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13371-1", "uniprot_id": "PHLP_HUMAN", "id": "Q13371-1", "name": "Phosducin-like protein", "aln": "MTTLDDKLLGEKLQYYYSSSEDEDSDHEDKD------RGRCAPASSSVPAEAELAG---EGISVNTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKSSVIGASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VUR7-1", "uniprot_id": "PHLP1_DROME", "id": "Q9VUR7-1", "name": "Phosducin-like protein 1", "aln": "MATLEDKLLGEKLEYYCSSSEGEDNGDEGGDNKGASGKSRCSGLTIDTNPDATPAGGFRQQSSTNTGPKGVVKDWQRFKQLEAERRDETERQRLALAKKLTITATTSAEDEE-RKRQEELDAELDELMS-------------EDFLQQYQKQRMAEMLRQTGHHQQFGQVQQLTSHEEFLACVEQENKHTTIIIHIYERQLAACATLNKCLDSLASDYPSIKFAKICSSVAGMSRDFRTKGLPALLVYKAQAVIGNFVRLTDDLSDDFFASDVESFLIEHGIIVDR------ALYN--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**:********:** *:**.**...*. * :.* : .. .:* ** : * *******::**:******:*:*:* *: * ***:::. : ::** :::*::*: ::. *: *:*****:**** ** :* : ** ** ::.* * ** :::*:* *::**** :.. ::* *: .**::**::**.:: *** * * * :.*****:**. :******:**:*.:**** *:*:** *.*:: :: :: * ", "identical_positions": 122, "similar_positions": 86, "identity": "39.35%" }, { "cls_id": "homologset.agr.RGD:621136", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESC1-1", "uniprot_id": "AGRL4_RAT", "id": "Q9ESC1-1", "name": "Adhesion G protein-coupled receptor L4", "aln": "-----------------------------------------------------------------------------MRLLLLLVGLSTLLN-HSYTQNC-KTPCLPNAKCEVLDEVAACFCS---------------------------------------------TGYTGN-----------GITICEDVDECNET-SVCGDHAVCENTNGGFSCFCVEGYQTSTGKTQFTPNDGSYCQDVDECNETSVCGDHAVCENTNGGFSCFCVEGYQT---------------STGKTQFTPNDGSYCQEIV---------------------------------------------------------------------------------------NSNCHLEHDCIAANINKTLKRIGPITEQLT----------LLHEIYKNSEAELSLVDIVTYIEILTESSSLQG---------------------YIKNTTSPKDAYFGSALTEFGKTVNNFVEKNTHEMWDQLPTNRRRLHLTKLMHAAEHVTLQISQNIQKNTQFDMNSTDLALKVFVFDSVHMKHTHPHMN-----VDGGYVKISPRRKSAYDPNGNVIVAFLCYRSIGPLLSSSDDFLLGAQS------------------DNSKGKEKVISSVISASISSNPPTLYELEKITFTLSHVKLSD--KHQTQCAFWNYSVDDMNNGSWSSEGCELTYSNDTHTSCRCSHLTHFAILMSPSTSIEVKDYNILTR------ITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAQLVFLVGININTNKLVCSIIAGLLHYFFLAAFAWMCIEGIYLYLIVVG----LIYNKGFLHKNFYIFGYLSPAVVVGFSASLGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFR---HTAGLKPEVSCYENIRSCARGALALLFLLGTTWTFGVLHVV------HASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFECLR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923X1-1", "uniprot_id": "AGRL4_MOUSE", "id": "Q923X1-1", "name": "Adhesion G protein-coupled receptor L4", "aln": "-----------------------------------------------------------------------------MRLLPLLVGFSTLLN-CSYTQNCSKTTCLPNAKCEVHNGVEACFCS---------------------------------------------QGYSGN-----------GVTICEDIDECSES-SVCGDHAVCENVNGGFSCFCREGYQTATGKSQFTPNDGSYCQDIDECSESSVCGDHAVCENVNGGFSCFCREGYQT---------------ATGKSQFTPNDGSYCQESM---------------------------------------------------------------------------------------NSNCHLEHACIAANINKTLKRIGPITEQTT----------LLQEIYRNSEAELSLMDIVTYIEILTESSSLLG---------------------HPNSTTSYKDAHFNSTLTEFGETINNFVERSTHKMWDQLPTNHRRLHLTKLMHTAELVTLQIAQNTQKNSQFDMNSTDLALKVFAFDSTHMKHAHPHMN-----VDGGYVKISPRRKAAHGTTGNVVVAFLCYKSIGPLLSSSDNFLLDTQN------------------DNSEGKEKVISSVISASISSNPPTLYELEKITFTLSHVKLSD--KHRTQCAFWNYSVDAMNNGSWSTEGCELTHSNDTHTSCRCSHLTHFAILMSSTSSIGIKDYNILTR------ITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLIGININTNKLVCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVG----VIYNKGFLHKNFYIFGYLSPAVVVGFSASLGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFR---HTAGLKPEVSCYENIRSCARGALALLFLLGTTWIFGVLHVV------HASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFGCLR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBW9-1", "uniprot_id": "AGRL4_HUMAN", "id": "Q9HBW9-1", "name": "Adhesion G protein-coupled receptor L4", "aln": "-----------------------------------------------------------------------------MKRLPLLVVFSTLLN-CSYTQNCTKTPCLPNAKCEIRNGIEACYCN---------------------------------------------MGFSGN-----------GVTICEDDNECG--------------------------------------------------NLTQSCGENANCTNTEGSYYCMCVPGFRS---------------SSNQDRFITNDGTVCIENV---------------------------------------------------------------------------------------NANCHLDNVCIAANINKTLTKIRSIKEPVA----------LLQEVYRNSVTDLSPTDIITYIEILAESSSLLG---------------------YKNNTISAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQKTTEFDTNSTDIALKVFFFDSYNMKHIHPHMN-----MDGDYINIFPKRKAAYDSNGNVAVAFVYYKSIGPLLSSSDNFLLKPQNY-----------------DNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHRKVTD--RYRSLCAFWNYSPDTMN-GSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYNILTR------ITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVG----VIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFR---HTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVV------HASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFGCLR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SY09-1", "uniprot_id": "AGRL4_DANRE", "id": "Q7SY09-1", "name": "Adhesion G protein-coupled receptor L4", "aln": "-----------------------------------------------------------------------------MKLLLFAAWFSSLLDPCRFLDIC--QSCHPNADCD-----DICKCR---------------------------------------------TGYTGN-----------GISDCRDDNECETVPEICGLHANCTNYVGGYYCNCLSGFISN-GTEQFQTNDGTSCNDINECEEDRKCGPNSKCHNNIGSFICSCLRGYTS---------------PAG-PWFMPNHGTDCIENS---------------------------------------------------------------------------------------KIHCHQDHKCTKETVNSTLERMTNLSISER----------LKEIRYQTS-AALSPVLLISYIEAMVSSKLNSG---------------------DVSKDSK---EHVNETITNLVFSVNNLVEKDEKVEWKKINEDLRMYYVTKLLHTAEKETLALSAGYTHATQMQVHAGDVEMKLYTFEPRQAQKHPLSAN-----IQGNSISLSTKKARHANNNGSTSVVFLIYHSIGDLLKPADDPGVADYSR-----------------YAAAGEITVNSPVIAAAISNQ--KTLPLNDVTFTLKHTQEIDPARDETKCAFWEYSPSMMG--HWSLDGCIRTRVNTTHTSCSCNHLTHFAILMSSARANLLAHYNVLTR------ITQLGMVISLICLSMCIFTFWFFRDIQNTRTTIHKNLCCSLFMAQFIFLIGINKSAHKWFCSLIAGLLHYFFLAAFAWMCIEGIHLYLIVVG----VIYNKGFLHRNFYAFGYGSPAVVVAISATLGYKYYGTSSVCWLSTENNFIWSFIGPAILIILVNLLAFAVIIYKVYR---HTAVKKPEISHYENIRSCARGAIALLFVLGVTWAFGVMYIL------YETTLTAYLFTFANVFQGMFIFIFLCVLSRRIQEEYYRLFKNMPCCFECLR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7G7-4", "uniprot_id": "LPHN_DROME", "id": "A1Z7G7-4", "name": "Latrophilin Cirl", "aln": "MLPTILSISYEHISLDLSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISAAQTSTTTNRPSPPPWVLSNGPPIFGNGSGLIHPPGVGAGAPPPPRLPTLPGVVGISGNPGLFNVPPQHTAVTHSTPSSSTTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQLHHHHNHHGEDTASPTKPSSKLPAGGNATSPSNTRILTGVGGSGTDDGTLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNINLNAAGMSGGDDESKLFCGPTHARNLYWNMTRVGDVNVQPCPGGAAGIAKWRCVLMKRIPDSGYDEYDDDISSTTPAPSGGDCLHNSSSCEPPVSMAHKVNQRLRNFEPTWHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFPDQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGKGRHIQLSQPITLTLKHLKTEN--VTNPTCVFWNYID-----HAWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSIFCGFITIFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQTPKVNCYYLLSYGLSLSVVAISLVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAGSTHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRGAGGVPASPSGSLHSRTAAASQVLFYPSYKKTKPGQPTGYPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQPEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : : * :*. : . * :** .:: . .. . .* :: . . * .: . ...*: : . . .:*. * .: * . : . * : . :. :..*. * . : . : .*:::.. * .: : : *.*: * :: :: : .. : :: :.: ::. : : :... :.: . * . :.* : : :*..: : . . : .. : : .: : :*:**.* : : .. *.**:* ** :** * **: * *.***:*****. :.:: .:*: : :* ::: :.:: ::.:**:*:..: .*: :::**:**: . . .*.:*: :** :*:. **:* *.:: * :.. : :: . :* :.* . **.:* :. * .. * * * :::: : . *:::* :.: .: : : :*. . * : .:* * ::.:*::*...* . ::: : : .* * *.: *::**:* *: ..:*:.** : .:: . *** ", "identical_positions": 100, "similar_positions": 239, "identity": "5.82%" }, { "cls_id": "homologset.agr.RGD:621137", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O09175-1", "uniprot_id": "AMPB_RAT", "id": "O09175-1", "name": "Aminopeptidase B", "aln": "MESSGPSSCHSAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLNGKATLELRCLLPEGASELRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQALCVVFPKPCCAAERFRLELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKCTYSALVEVPDGFTAVMSASTWERRGPNKFFFQMSQPIPSYLIALAIGDLASAEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFNRWLNTPGWPPYLPDLSPGDSLMKPAEELAELWAASEPDMQAIEAVAISTWKTYQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDHQEEFWKVKDFLQSQGKQKYTLPLYHAMMGGSEMARTLAKETFSATASQLHSNVVNYVQQILAPKGS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCT3-1", "uniprot_id": "AMPB_MOUSE", "id": "Q8VCT3-1", "name": "Aminopeptidase B", "aln": "MESGGPGNYSAAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLSGTATLELRCLLPEGASELRLDSHSCLEVTAATLRRGQPGDQQAPAEPVPFHTQPFSHYGQALCVAFRQPCGAADRFELELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKCTYSALIEVPDGFTAVMSADTWEKRGPNKFFFQMSHPIPSYLIALAIGDLASAEVGPRSRVWAEPCLIEAAKEEYSGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMNVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQDQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAELWVTSEPDMQAIEAVAISTWKTYQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDYQEEFQKVKDFLQSQGKQKYTLPLYHAMMGGSEMARTLAKDTFAATASQLHSNVVNYVQQILAPKDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4A4-1", "uniprot_id": "AMPB_HUMAN", "id": "Q9H4A4-1", "name": "Aminopeptidase B", "aln": "MASGEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHSNVVNYVQQIVAPKGS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *. . .******************.*****:*****************.*****.*.*.*:**** ****:*******.**** **:* * :**.:: :***.*:************* * :** **:*:.: ************************************************* .****:************.***:**********.:**************.*****************:******.***********************************************************************************************************************:::*******************************:*************:***.******.****:****:***:************ ** ******:*****************************:**.:.* **:********.****************************:***.****:***********:****:**:* ***:**:.*******************:*:****:**::****************:***.*", "identical_positions": 562, "similar_positions": 67, "identity": "86.46%" }, { "cls_id": "homologset.agr.RGD:621138", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18894-1", "uniprot_id": "OXDA_MOUSE", "id": "P18894-1", "name": "D-amino-acid oxidase", "aln": "MRVAVIGAGVIGLSTALCIHERYHPT-QPLHMKIYADRFTPFTTSDVAAGLWQPYLSDPSNPQEAEWSQQTFDYLLSCLHSPNAEKMGLALISGYNLFRDEVPDPFWKNAVLGFRKLTPSEMDLFPDYGYGWFNTSLLLEGKSYLPWLTERLTERGVKLIHRKVESLEEVARG-VDVIINCTGVWAGALQADASLQPGRGQIIQVEAPWIKHFILTHDPSLGIYNSPYIIPGSKTVTLGGIFQLGNWSGLNSVRDHNTIWKSCCKLEPTLKNARIVGELTGFRPVRPQVRLEREWLHFGSSSAEVIHNYGHGGYGLTIHWGCAMEAANLFGKILEEK-KLSRLPPSHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35078-1", "uniprot_id": "OXDA_RAT", "id": "O35078-1", "name": "D-amino-acid oxidase", "aln": "MRVAVIGAGVIGLSTALCIHERYHPA-QPLHMKIYADRFTPFTTSDVAAGLWQPYLSDPSNPQEAEWNQQTFDHLQSCLHSPNAEKMGLALISGYNLFRDEVPDPFWKSTVLGFRKLTPSELDMFPDYSYGWFNTSLLLEGKSYLSWLTERLTERGVKFIHRKVASFEEVVRGGVDVIINCTGVWAGALQADASLQPGRGQIIQVEAPWIKHFILTHDPSLGIYNSPYIIPGSKTVTLGGVFQLGNWSELNSVHDHNTIWKSCCQLEPTLKNARIMGELTGFRPVRPQVRLERERLRFGSSSAEVIHNYGHGGYGLTIHWGCAMEAANLFGKILEEK-NLSRMPPSHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14920-1", "uniprot_id": "OXDA_HUMAN", "id": "P14920-1", "name": "D-amino-acid oxidase", "aln": "MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEK-KLSRMPPSHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BGT3-1", "uniprot_id": "A2BGT3_DANRE", "id": "A2BGT3-1", "name": "D-amino-acid oxidase", "aln": "MRVCIIGAGVIGLSTAQSIYQHFHSRVSPLTIEVYADIFTPLTTSDGAAGFWQPYLYDKGNVKETQWNKETFNYLLSFLNSPDSIKMGIFLESGYNLCFEPMPEPSFKQAVLGFRQLSKRELEMFPGFSFGWFNTALVIEGKSYLPWLMDWLNQRGVKFFQRKIDSFKELSDSGADMIINCSGVRSGDLQPDPELQPARGQIIKVDAPWLKHWVITHDSKLGTYNTPYIIPGSRLVTVGGVFQVGNWNRMNSSVEHKQIWEGACKLEPSLQHARIVEDWTGLRPARSKVRLERESIRCGGHSFEVIHNYGHGGFGLTIHRGCAEEAARLFGQFLEQKGLLTSQAKSRL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :*********** .*::::*. .** :::*** ***:**:* ***:***** * .* :*::*.::**::* * ::**:: ::*: * ***** : :*:* :*.:*****:*: *:::**.:.:***:*:*::***.** ** : *.:****:::**: *::*: .*:*:**:** :* ** *. ***.****::*:***:**:::***.. * **:******:: **:**:**:***. :*. :*: **:..*:***:*::***: : **:**.*.::***** :: * . **********:***** *** ***.***::**:* *: . *:*", "identical_positions": 182, "similar_positions": 112, "identity": "52.3%" }, { "cls_id": "homologset.agr.RGD:621139", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIM4-1", "uniprot_id": "BSND_MOUSE", "id": "Q8VIM4-1", "name": "Barttin", "aln": "MADEKTFRIGFIVLGLFLLSLGTFLMSHDRPQVYGTFYAMGSVMVIGGVIWSMCQCYPKITFVPADSDFQGILSPKALSLLETGLS-EVKSP--QPPYVRLWEEAAYDQSLPDFTHIQMKVMGYSEDPRPLLAPEL---KTGASSVREGEPRTAQAWMEAPVVVHRGSDENEGEKSHSQSSPS--VGPQGSAPLASFHDDLDVGSSEGSSLQPSP-NRDEPH--RQVPWASRGPLDRFSDFALIDDTPTSEDTVLDGQAREAALPRKQQWSLRMKGETVQA---RAEEPEQEEEDLYYGLPDSPGNPLPDKELGFEPDIQG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R2H3-1", "uniprot_id": "BSND_RAT", "id": "Q8R2H3-1", "name": "Barttin", "aln": "MADEKTFRIGFIVLGLFLLSLGTFLMSHDRPQVYGTFYAMGSIMVIGGVLWSMCQCYPKITFVPADSDFQGMLSPKALSLLETGLS-EVKSP--QPPYVRLWEEAAYDQSLPDFTHIQMKVMGYSEDPRPLLAPEL---KTGTSSAKEGEPHSAQTWMEAAVVVHRELDEKEGEKSRSQSSPP--ACSQGSAPLASFHDDLDVGSSEGRSPQPSPPDRDEAH--LQVPWASRGPLDRFGDFALIDDTPISEDMGLEGQAQEEALPSKQPWSLRMKEETVQA---GAEEPEQEEEDLYYGLPDSPGDPLPDKELGFEPDVQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WZ55-1", "uniprot_id": "BSND_HUMAN", "id": "Q8WZ55-1", "name": "Barttin", "aln": "MADEKTFRIGFIVLGLFLLALGTFLMSHDRPQVYGTFYAMGSVMVIGGIIWSMCQCYPKITFVPADSDFQGILSPKAMGLLENGLAAEMKSPSPQPPYVRLWEEAAYDQSLPDFSHIQMKVMSYSEDHRSLLAPEMGQPKLGTSDGGEGGPGDVQAWMEAAVVIHKGSDESEGERRLTQSWPGPLACPQGPAPLASFQDDLDMDSSEGSSPNASPHDREEACSPQQEPQGCRCPLDRFQDFALID-APTLEDEPQEGQQWEIALPNNWQRYPRTKVEEKEASDTGGEEPEKEEEDLYYGLPDGAGDLLPDKELGFEPDTQG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************:**********************:*****::*********************:*****:.***.**: *:*** ********************:*******.**** *.*****: * *:*. ** * .*:****.**:*: **.***: :** * . .**.******:****:.**** * :.** :*:*. * * ..* ***** ****** :* ** :** * *** : * * * :* .****:***********..*: *********** **", "identical_positions": 217, "similar_positions": 46, "identity": "67.6%" }, { "cls_id": "homologset.agr.RGD:621140", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYS7-1", "uniprot_id": "D3ZYS7_RAT", "id": "D3ZYS7-1", "name": "Ras GTPase-activating protein-binding protein 1", "aln": "MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYAHGGLDSNGK-------PADAVYGQKEIHRKVMS--QNFTNCHTKIRHVDAHAT--LNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFG------------------GFVTEPQEESEEEVEEPEERQQSPEVVADDSGTFYDQT-VSNDLEEHLEEPVVEPEP--------EPEPEPEPEPVSDIQEDKPEPA--LEEAAPEDVQKSA-SPAPADVAP-AQEDLRTFSWASVTSKNLPPSGAVPVTGTPPHVVKVPASQPRPESKPDSQIPPQRPQRDQRAREQRIN-IPPQRGPRP---------IREAGEPGDVEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQSYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLNNRPIMFRGAVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGPSGGMRGPPRGGMVQKPGFGVGRGITT-------PRQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97855-1", "uniprot_id": "G3BP1_MOUSE", "id": "P97855-1", "name": "Ras GTPase-activating protein-binding protein 1", "aln": "MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYAHGGLDSNGK-------PADAVYGQKEIHRKVMS--QNFTNCHTKIRHVDAHAT--LNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFG------------------GFVTEPQEESEEEVEEPEERQQTPEVVPDDSGTFYDQT-VSNDLEEHLEEPVVEPEP--------EPEPEPEPEPVSDIQEDKPEAA--LEEAAPDDVQKST-SPAPADVAP-AQEDLRTFSWASVTSKNLPPSGAVPVTGTPPHVVKVPASQPRPESKPDSQIPPQRPQRDQRVREQRIN-IPPQRGPRP---------IREAGEPGDVEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGAVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGPSGGMRGPPRGGMVQKPGFGVGRGITT-------PRQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13283-1", "uniprot_id": "G3BP1_HUMAN", "id": "Q13283-1", "name": "Ras GTPase-activating protein-binding protein 1", "aln": "MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGK-------PADAVYGQKEIHRKVMS--QNFTNCHTKIRHVDAHAT--LNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFG------------------GFVTEPQEESEEEVEEPEERQQTPEVVPDDSGTFYDQAVVSNDMEEHLEEPVAEPEP--------DPEPEPEQEPVSEIQEEKPEPV--LEETAPEDAQKSS-SPAPADIAQTVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQRDQRVREQRIN-IPPQRGPRP---------IREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQSYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGLGGGMRGPPRGGMVQKPGFGVGRGLA--------PRQ-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKD5-1", "uniprot_id": "A0A8M2BKD5_DANRE", "id": "A0A8M2BKD5-1", "name": "", "aln": "MVMEKPSAQLVGREFVRQYYTLLNQAPDYLHRFYGKNSSYVHGGLDNNGK-------PAEAVYGQSEIHKKVMA--LSFRDCHTKIRHVDAHAT--LNEGVVVQVLGELSNNMQPMRKFMQTFVLAPEGTVANKFYVHNDIFRYQDEVFG------------------DSDSEPPEESEEDVEEL-ERVHSPEVVQEESSGYYEQT-PCVEPEVPQEEVSVTPEP--------QPEPEVEVEPEPAAVELKAEPISQPEVHVEEKTQRSPPSPTPADTAPTMPEDNRPSSWASVTSKNLPPGGVVPATGVPPHVVRVPSAQPRVEVKTETQTTAQRPQRDQRPRDQRPGPSPAHRTPRPGGVQNSNELMVREGESGESEVRRTVRYPDSHQLFVGNVPHDVDKNELKEFFEQYGTVLELRINSGGKLPNFGFVVFDDSEPVQKILNNRPIKLRGDVRLNVEEKKTRSAREGDRRDIRPRGPGGPRDRIGGSRGPPTRGGMAQKPSFGAGRGTGPSEGRYTGPRQ-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53741-1", "uniprot_id": "BRE5_YEAST", "id": "P53741-1", "name": "UBP3-associated protein BRE5", "aln": "---MGVTVQDICFAFLQNYYERMRTDPSKLAYFYASTAELTHTNYQSKSTNEKDDVLPTVKVTGRENINKFFSRNDAKVRSLKLKLDTIDFQYTGHLHKSILIMATGEMFWTGTPVYKFCQTFILLP-SSNGSTFDITNDIIRFISNSFKPYVLTDASLSQSNEENSVSAVEEDKIRHESGVEKEKEKEKSPEISKPKAKKETVKDTTAPTESSTQEKPIVDHSQPRAIPVTKESKIHTETVPSSTKGNHKQDEVSTEELGNVTKLNEKS-HKAEKKAAPIKTKEGSVEAINAVNNSSLPNGKEVSDEKPVPGGVKEAETEIKPIEPQVSDAKESGNNASTPSSSPEPVANPPKMTWAS--------KLMNENSDRISKNNTTVEYIRPETLPKKPTERKFEMGNRRDNASANSKNKKKPVFSTVNKDGFYPIYIRGTNGLREEKLRSALEKEFGKVMRITAADNFAVVDFETQKSQIDALEKKKKSIDGIEVCLER-KTVKKPTSNNPPGIFTNGTRSHRKQPLKRKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *:::** :. *. * **...:. .* . :.:.. *: * *:.:*:: . .. . : *: :* : * *:..::: . * : . .: :* ***:* * .: ...* : ***:*: .: * . * . *. **: *: ::**: .: : . . *: . . :.: . * * . : * : * . :... : . * :: : :*....** . *. * *: . :: : :: . : . . . *.: . : . .. : . *.: .. * :..: .: :: . .. : : * : .* : : .:: ::: . .: . :.: .. :. : : :. : . : .* * .:** . * : ", "identical_positions": 58, "similar_positions": 168, "identity": "10.96%" }, { "cls_id": "homologset.agr.RGD:621141", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIH7-1", "uniprot_id": "WNK1_RAT", "id": "Q9JIH7-1", "name": "Serine/threonine-protein kinase WNK1", "aln": "----------------------------------------------------------------------------------------------------------MSDGTAEKQSGTPG--FLSPPAPVPKN--------------------------------GSSSDSSVGEKLGAAVADSGIGRTEEYRRRRHTMD------------------------KDSRGAAATTTPTEHRFFRRSVICDSNATALELPGLPLSIPQPS------------------------------------------------------------VPAVVPQSAPPEPHREETLTATVASQVSQQPSAAASPGEQAVVGSATATVPSSTS--KDRPVSQPSLVGSKEEPP------PSRSGSGSGGASAKE------------------PQEERNQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEED----DGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKRKQEESSFKQQNEQQASVSQAGIQPLSVASTGIPTAPTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYG----SQHEQAHSIGTAPG-------HTVSSIQAQ----SQPHG-------------------------------------------------------------------------------------------------VYPPSSMAQG----------------------------------------------QNQGQPSSS-LAGVLSSQ----PVQHPQQQ-GIQPTVPPQ-QAVQYSLPQAASS-SEG-TVQPVSQP-------------------------------------QVSAGTQS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STQGVSQAAPPEQTPITQSQPTQPVP------LVSSVDSAHSDVASGMSDGNENAPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVAQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFPGSQKLEGEFKQPIAVSSMPQQIGVPTSSLTQVVHSAGRRFIVSPVPESRLRESKIFTSEIPDPVAASTSQG----PGMNLSHSASSLSLQQAFSELKHGQMTEGPNTAPPNFNHPG---PTFSPFLTSIAGVQTVAASTPSVSVPITSSPLNDISTSVMQSEGALPTDKGIGGVTTS-TGVVASGGLTTLSVSETPTLSSAVSSSTAPAVVTVSTTSQ--PVQASTSGSIASSTGSFPSGTFSTTTGTTVSSVAVPNAKPPTVLLQQVAGNTAGVAIVTSVSTTTPFPAMASQPSLPLGSSTSAPTLAETVVVSAHSLDKASHSSTAGLGLSFCAPSSSSSSGTAVSSSVSQPGIVHPLVISSAIASTPVLPQPAVPTSTPLLPQVPNIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEMDADTQSKAPGIDDIKTLEEKLRSLFSEHSSSGTQHASVSLETPLVVET-VTPGIPTTAVAPSKLMTSTTSTCLPPTNLPLG-TAGMPVMPVGTPGQVSTPGTHASAPASTATGAKPGTTPPKPSLTKTVVPPVGTELSAGTVPCEQLPPFPGPSLIQTQQPLEDLDAQLRRTLSPETIPVTPAVGPLSTMSSTAVTEAGSQPQK---DGTEVHVTASSSGAGVVKMGRFQVSVTMDDAQKERKNRSEDTKSVHFESSTSESSVLSSSSPESTLVKPEPNGITVSGISLDVPDSTHRTPTPEAKSETGQPTKVGRFQVTTTAN-KVGRFSVSRTEDKVTELKKEGPVTSP-FRDSEQTVIPAAIPKKEKPELAEPSHLNGPSSDLEAAFLSRGGEDGSGSPHSPPHLCSKSLPIQTLSQSLSNSFNSSYMSSDNESDIEDEDLRLELRRLREKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGN--LSGQSGTSVLNPQQTLHPPGNTPETGHNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQG---------------------------------------------TSSTNTVGGTVSSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLS-GRRGSKGHMNYEGPG----------MARKFSAPGQLCISMTSNMGGSTPISAASATSLGHFTKSMCPPQQYGFPAAPFGTQWSGTGG-------PAPQPLGQFQPVGTTSLQNFNISNLQKSISNPPGSNLRTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83741-1", "uniprot_id": "WNK1_MOUSE", "id": "P83741-1", "name": "Serine/threonine-protein kinase WNK1", "aln": "----------------------------------------------------------------------------------------------------------MSDGAAEKQSGTPG--FLTPPAPVPKN--------------------------------GSSSDSSVGEKLGATVADSGVGRTEEYRRRRHTMD------------------------KDSRGAAATTTPTEHRFFRRSVICDSNATALELPGLPLSIPQPS------------------------------------------------------------VPAVVPQSAPPEPHREETLTATVASQVSQQPSAAASPGEQAVVGSATTTVPSSTS--KDRPVSQPSLVGSKEEPP------PSRSGSGSGGASAKE------------------AQEDRSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEED----DGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKRKQEESSFKQQNEQQASVSQAGIQQLSAASTGIPTAPATSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTIDSGQGSSVFTESRVSSQQTVSYG----SQHEQAHSTGTAPG-------HTVSSIQAQ----SQPHG-------------------------------------------------------------------------------------------------VYPPSSMAQG----------------------------------------------QNQGQPSSS-LAGVLSSQ----PIQHPQQQ-GIQPTVPSQ-QAVQYSLPQAASS-SEGTTAQPVSQP-------------------------------------QVSAGTQLPVSQTVATVQGEPHIPVSTQPSVVPVHSGAHFLPMGQPIPTSLLPQYPVSQIPISTPHVSTAQTGFSSVP-----------------------------ITMAAGINQPLLTLASSATASSIPGGSPVVPNQLP------TLLQPVNQLQSQVHPQLLQPTTVQSIGIPANLGQAAEGPLPSGDVLYQGFPSRLPPQYPGDS--------------NIAPSSNVASVCIHSTVLAPPSMPTEALATQGYFPTVVQPYVESTPLVPMGSVGGQVQVSQPAVSLTQQPPTTSSQQAVLESTQGVSQAAPPEQTPITQSQPTQPVP------LVTSADSAHSDVASGMSDGNENAPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVAQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFPGSQKLEGEFKQPIAVSSMPQQIGVPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFTSDISDPVVASTSQA----PGMNLSHSASSLSLQQAFSELKHGQMTEGPNTAPPNFNHMAG--PTFSPFLASIAGVQTVAASTPSVSVPITSSPLNDISTSVMQSETALPTEKGIVGVTTTSTGVVASGGLTTMSVSESPTSSSAVSSSTVPAVVTVSTPSQ--PVQASTSGSIASSTGSFPPGTFSTTTATTMGSVVAPDAKPPTVLLQQVASNTAGVAIVTSVSTTTPFPGMASQPSLPLSSSTSAPTLAETMVVSAHSLDKASHSSTAGLGLSFCAPSSSSSSGTAVSTSVSQPGMVHPLVISSAVVSTPGLPQPVVPTSTPLLPQVPNIPPLVQPVVNVPAVQQTLIHSQPQPALLPNQPHTHCPEMDADTQSKAPGIDDIKTLEEKLRSLFSEHSSSGTQHASVSLETPLVVETTVTPGITTTAVAPSKLMTSTTSTCLPPTSLPLG-AAGMPVMPVGTPGQVSTPGTHASAPVGTATGVKPGTTPPKP--TKTVVPPVGTELSAGTVPCEQLPPFPGPSLIQSQQPLEDLDAQLRRTLSPETITVAPAVGPLSTMSSTTVTEAGTRLQK---DGTEGHVTATSSGAGVVKMGRFQVSVTMDDAQKERKNRSEDTKSVHFESSTSESSVLSSSSPESTLVKPEPNGISISGISLDVPDSTHKAPTPEAKSDAGQPTKVGRFQVTTTAN-KVGRFSVSRTEDKVTELKKEGPVTSPPFRDSEQTVIPAVIPKKEKPELAEPSHLNGPSSDLEAAFLSRGTEDGSGSPHSPPHLCSKSLPVQNLSQSLSNSFNSSYMSSDNESDIEDEDLRLELRRLREKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGN--LSGQSGTSVLHPQQTLHPAGNTPETGHNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQG---------------------------------------------TSSTNTVGGTVSSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLS-GRRGSKGHMNYEGPG----------MARKFSAPGQLCVPMTSNLGGSTPISAASATSLGHFTKSMCPPQQYGFPPAPFGTQWSGTGG-------PAPQPLGQFQPVGTASLQNFNISNLQKSISNPPGSNLRTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4A3-1", "uniprot_id": "WNK1_HUMAN", "id": "Q9H4A3-1", "name": "Serine/threonine-protein kinase WNK1", "aln": "----------------------------------------------------------------------------------------------------------MSGGAAEKQSSTPGSLFLSPPAPAPKN--------------------------------GSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMD------------------------KDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPS------------------------------------------------------------IPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTS--KDRPVSQPSLVGSKEEPP------PARSGS--GGGSAKE------------------PQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEED----DGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQ-SSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYG----SQHEQAHSTGTVPG-------HIPSTVQAQ----SQPHG-------------------------------------------------------------------------------------------------VYPPSSVAQG----------------------------------------------QSQGQPSSSSLTGVSSSQ----PIQHPQQQQGIQQTAPPQ-QTVQYSLSQTSTS-SEATTAQPVSQPQ------------------------------APQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLP-----------------------------ITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLP------TLLQPVTQLPSQVHPQLLQP-AVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDS--------------NIAPSSNVASVCIHSTVLSPP-MPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQAP-TTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTT------LASSVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQS----PGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAAT--APVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATS-TGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLCIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLG-TVALPVTPVVTPGQVSTP------VSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQVTTTAN-KVGRFSVSKTEDKITDTKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGSPHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQLSGN--LSGQSAASVLHPQQTLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQG---------------------------------------------TSSTNTVGATVNSQAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLS-GRRGSKGHMNYEGPG----------MARKFSAPGQLCISMTSNLGGSAPISAASATSLGHFTKSMCPPQQYGFPATPFGAQWSGTGG-------PAPQPLGQFQPVGTASLQNFNISNLQKSISNPPGSNLRTT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXY8-1", "uniprot_id": "A0A8M9PXY8_DANRE", "id": "A0A8M9PXY8-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------------MSS---ENPNKVVT--FLAPPPPKNVN--------------------------------GSGSDSLVGEKL-----------DTEVRKRRHTMD------------------------KDLK-------TAEHRFFRRSVICDSNATALDLPSKACILTSPPDCEQFV------------------------------------------------------IPTVLSSTPDVTLDTQTVVSAAVVEERSEDERRAGVEGIVEVQSPSVQDAGSRQSEVLGKVETELSDVGDKEQESRVTDKQEEEERGVAKARAEAE------------------LREAVKKEQDEIEEVETKAVGTSPDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLSRSERQRFKEEAGMLKGLQHPNIVRFYDSWESPSKGRKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLHFLHTRAPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRSSFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNPAQIYRRVTSGVKPGSFDKVAIPEVKEIIEGCIRQNKDERYAIKDLLNHAFFQEETGVRVELAEED----DGEMIAIKLWLRIEDVKKLKGKYKDNEAIEFSFDLHRDVPDDVAQEMVESGYVCEGDHKTMAKAIRDRVSLISRKREQRQQVRAEQEKRKQEE-----EQKLLSSESIKNVAGAQGTQGSLQSQCSSQPPTPGLVQPECEEPDADPQHQYMQSGIT-LADGTFDSGQGSSVFSEPHLS-QLSMSYSSPGTSQQQQVPGQGTYTPSSQAPQQHTAYPQQPMPQSVSQPYGGGGSGLVEPPLFFPTIPERPVSFSPPPSCPPKAFNVQRRKSTSILEAHTRHFQPAYHRSYGSSLHPFSGVEALGATVEPSMFMMPGMPAQRLADPLHLQPPTESLYGYKDVRAEQEETVRRLSLNQAALMDHLEAMAYSGYPMTAHQLSHISFHQQMQAAAASLAYETQSQQPGPAYLHPHLQSHMRLTHSPIPQLPPMSVPSSASAPQQATVADPSYQSHSFPHSAPPVLAHASEPNTAFEFHMHNLQADPAMLASRLYRARRGSMDLNLEEAGGNPGLCSRLQPVTEELYSYVSPELPLPPGSLLLHGPKELSPEPSSDSMTSSDAGEFHSPPPHQLYQTQECSAAQSIPQAAYYKTDGGSNVSDGHPPSQPTFLFVPHSESSTISSSHINAWARQPSLPPDLTFHEPALSHQGATLVQVPIPQSTSGMSLASCSTPAASASQQYGVYYVQALPTQAPVQQPASLGPTSQPCASLPQQQTPQQPSSTVAQSISQTQITPTQLCSPALCVPTIAVTPFQQQPVPEALTSLKTAPATSPSMLPPHVPLLVTTPVPTIHVATVPSPTEHPCLPADALAQTSHSASQTLTTELSQLQTPAVESSHSDVASGLSDGNEGVTG--GRHEGRPAKRHQRRSVRSRSRNEKTSKVKLSVLNISSMGDRVAECQLETHNRKMVTFKFDLDGDNPEEIAQIMVQSEFILESERESFIDRIREVIETADEKG-----VERERSQ-----------MASDHEQLMPTTSAPLEHG-RTYNLSVPPSSAAQVVHSAGRRFIVSPVPESRLKDQFFSPSQPTIPLHEEPAPVPVALPALGLSVSASAVSLQQAFTEMRQAHFDPGPSTAPPMLHNSMP------PLLPATT------------PLPSSATP-----------------------------------------VVSPPVSSEVTSSPSLPSIN--------------------------PPVSSSPPPTVPVNSVTSP----PAQLTLPQSQVAPAVISVIPTPSTLPMPAVPTATSLPQTSVTVP-------------------SSTP------IAPMGSVSGGSGE-----QPSIPATSSPTSATIQTPQLAPSTIPTTT----AQSQVPPLQPVTTTMPVVQPTPVHSQPQTTTVPNQSHAHSVECDSDQQGK---VDDIQALDKKLRSLFMDLGS-----GPPSAQSDVTSDPTATPSVPGTSSP--TTCATPSGTPLPPSSLPLNSSTQSAGSPMTSMGNASTP------------VGYSQTTPSKAPLTRLPVLPVGPDQ-AGTPPTEHLPPFPGPGLIQSQQPLEDLDAQLRRALSPETVPIS----SVTHQSSLTGMPPGGQPVP----FSLDDEQAAAPAAGGYKLGRFQVSVATDENTTQTPTSSSSSTSSSSTTSSS-SSSCSLSSPENTLHRTSSPLIDTG---ADVVDGLPALPN--QTTTQPQPTTIGRFQVTTKTDTQVGRFSVSKAQDEVTTSTSQ-------------------------PQPTPQTHS----------------AVGNGPAQSP--------------GSLNNSISS-YFSSDNDSEFEDEDFKREVSRLRDKHMIESQALYSRQKAEIEALFARLGKVPPAMVNPPVVNPAGRRRRPTKSKSSKSSRGSSQASKSPVQPATSTLSAQSAPSVYPAQQAFLAPGGMMDGGSSPLLQSFKPSPSNDNLCSTFTSDATLSAPSLCVTSQGCVKFSCGSERVTFKPGGRRTRFLSTPCLALWKMVKKVCPCNQLCRTSSTNTVAG--PGQNQSQPPVSQSQSCKGMFTDELHKLVDNWARDAMNLSQGKRGSKHQQQVVPQGHSYEMVPPVNMGRKYSAPGQLCPSIASTLSGHPPMPNTPATSLGARKGSLCPTPQYGYPSAPYSAQWAGAATHTQAGLLATSQPLGQYPQVPTP-LQTFHISTLQKSVSHPGGPNLKST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PGC5-1", "uniprot_id": "WNK_DROME", "id": "M9PGC5-1", "name": "Serine/threonine-protein kinase Wnk", "aln": "MGQTLCDFVRQQEVVPANRARKGSAISEDGTTSCTTQPQRNTSISSEEQTVQGANIQKSGHRSFNRSASSRQKPNPTSKLKDTLNRKPTCKQGTLSAHTSTSSTTSIQSSPIEPASSLPTLNTTPTPPAASKSNLFVRVLRRFSNNTLPGKTASSPKNVDDVPKVNDNNNGDLGKQQSTDVEVLCSQDNQSREQNEDEMDSKIEPADAISNQKAGLTSGKPKKDKSVKGTSQAVVSDTKKMEARKSSSDTVIEPLIKQQAPLHSSKTTPTTLTANFVQNIRFVRKNVEQSGRNTNPLQFVELETEFPRDYDDNIEMLSREAEHLEEQFRTPTRSNATDATSHHVAGIIDNIITEASRSLTIEKTEDDVPLKSSTKHSSGVKRVGFQVEDKDDTEVQSEKQAKSFDDITKKAESSEASAEEAAVTGSSTDASASPLPSTSLVSTTSSATSITKSKSDEDDDPVAMSPCGRFFKYDKEVGRGSFKTVYRGLDTLTGVPVAWCELLDKQVKKSERTRFREEADMLKKLQHPNIVRFYTYWEFPIGRKKNIVLVTELMLSGTLKSYLKRFKKIHPKVLKSWCRQILKGLNFLHTRQFPIIHRDLKCDNIFITGTTGSVKIGDLGLATLKNRSHAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMAISEYPYSECKGPAQIYKKVISGIKPAALAKVEDPNVRDIIERCIELKKEDRPSCNELLESEFFDEDIGIRVEPTASEQFLSDPSISIIEFRLRFMDPKKRSSRHKENEAIQFEYNIRHDEYEQIAQEMMKENIISEDDSRAVARLLKVQVVSLLKERAQRQTQIKLQNEKSRLEKLALQKQRESLPTNVDEDEEEEEESEDEEDGVKWNQRLQLRYDLLNTDSETSLALSTNSVEPQQLSTRSNTSIPNSGIQQPVQVPGQVPVSQLISVQPQAIPSPAIPMQQK-------PTVHYIQPPQLASYQNSN-------------------------------------------------------------------------------------------ASMQEMTNNQVISPTG----------------------------------------------SQQMQQQQPVVAPTVNHQ------VMPQQQVNQQQQQPQMMQQIPQQVQVQQPQ--TVLPPQPHEQQP-----------------------------------QQQQQPLQQQLQQLMHTNVQAPDLTQQQQMAQQQAQQYFQQQQQQPQQAVNMQQAYAMQQAGQQQQ-------------------------------------------------------------------------------------LSQPLQIQQQILQQQQVAVSHQQQIMQQQLAQHQLQQLQQQQLQQQQLQQQQQIQQQQLQ-------------------------------------------------------------------------------QQQLQQQQFVQQYAQAMPQQQHQQLVTGSQVMAPHQHQQPIQ------IPVQMQVPPTSVAPPIQHTYNQQGGQVTLSDAQQQQHPGFSAVPQQAAPFIQQPTQQPIQLSMPLEQQLQQLLHSQPAQQQQAMSQQQQQPLVQQQQLPLVQQQPPLVQQQQPLVQHQQPSVQHQQPLVQ-----------------------QPQQQQPQPQNQQPQPQTQQTHVVQQQPPQQQPAVEQISQISSQVPVQQENLQPIQVNKDANVATDAMSLNSAHG-----ALEPAPKTEPQNSADAEKQQKQTGTGTRSQKPRRSNRSG--NERIPKLSVTSVDEGSVINCHMENKLKTITFKFDIGDVNPVEIAN--------------------------KLIAQDLLSNCQSTVFVEMINEIVDQVK-----------------QNPNQIPIPTNYRRNIEKVRHASLTRQRSTFRSHQRHRSRDETASDITKMFEPTIHGVETLPSGGGGAEQSNCNLTLEARSHLSNIPNAKEPQLNVSTPPTTTSTMSSSSTASRDAPNSSNDVTIGSGSVSRKTSTASEYTSLSIDYMPDSNITPTGPEPPLDDGKDKKPCSLAIARMQKLLESAGNGAPRSLNLPLNRHLKIQEDLKHTRSLDDLTAVKITFDMPNKAALDTSENAQQATEAEAEKPKDKSGQAVGNQGTGAANTLEQLKIELENITHAHAFASAVVASIN-----------NRAPHQASPAMSSLKATSGQPQTQEITKPNNGAG--PSVPSVGQNTPTAALTSARGSGSSVYNSRRTSIDNSVGSDMHLHTATNLEGTVSNPD---PIPTEASVGITIATGHEKQLSKQPSLEKPSATSILTNNSDPPQRNPSNGSINQNSIADLEKKLAALRNTEN-------TEESATATLSVVPKQVEEVVNPSARKISRFSVSRVQE---QKTSTGVEEPAQGQLKIDLQVAGPGGQVQTNNSVQNGSVVNTPTEVISSPIQNVPLAINGIQLMYQQPQQIHQLPGGTSTTTSGAGTQCIVVPQVVNQNGTHVQQPSNLQPQQQSVHPNMTQQPQQTPLNGHPSMVNTLQQQPPQQSLPMQTIQSQQQQHNQMPIISQQQQQQILMQQQQQQGSQQGSQQFNLPGTQQTHPQHQFIQSQPNQLHSLPPQVVSMAQGNLPHQLPPMQTMGAQQQMISQQQHQLQMQSHMHQQN---------------------------------VPGMYNQQTGARVAAPQNFAGAVPNHLLQQSPLMASQQPAQPMQHVMQPIFNATSGEVTEEPVSLAATHPHLLPSDIQS-------DIKHNLDSLVNQLCNTRLGTNQHQRLLLLRQRQLIEEDELRLKHYVEYEKFQKALRQSISTNVP-----------ANAAYYSAAAAQLPTNLAAPAAPSSSNPTSTSSANT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. * . ..*.. . ....:. :*:: . .:... ** *. : . ::: *. .*: .* . .... ... ..:. . : : :.. . : ..: . : . ..*: . .. : . .. .. .: : ..*. * ***:*:* *:*********:**** * * ****** *:::.:*** **:*** *** ********** ** . :* ******** *****:****** :: ***:**********:***** ****************.***************. *.******************:****************** ********:..****::* **:**.:: ** *:*::*** **. :*::* : ::**: **:*: *:*** : .: * . *:: **: * ** ..::*:****:*.:::.:* :::****::.. :.*.* :::*: :: :* : ::* *** *:::.: * : . . . . . . : :.: . . *: : * .*.: ::. * .:* .* . *. * . * .* * . :: . * *: * : . * .: . :* * : : . . : . *. : . :.**. :.. : . :.: :: :* .:: . : : ::: : . :: ::. : : :: :*:.: * :::.:: : : :: : . :: . * . : ... .*.. .: ** :..*: . . . . *. :..: . :.* :* :: : *. : * : * *. : : : : *. *: : * .. . . . :. * : . :. . .. * .:. . .. .. . . : *. : . : .: : :.. . . : ::: ..* .* : . : . :. : . . . :.: . .* : .. : .* ::*. . . * : . *..*. . . .* . .. . ... .: . . : . : .:* * * *: . . *. . * . .* . .. :* ... .. . .. .:.**.*: : : *.. : . : .: . . .. .: *. .: ...* . ::. : ::. : : . : : : .: . .:::: .:..:.*. ..:. ... * .:* . . . . * : : * : . . ::.: . *. .::.:.... .: . * :.. : . :: :.: : :. : . . .:: : . * .*** . .. : : : :* . . : . . : . :. * . : * *:* ... .*", "identical_positions": 315, "similar_positions": 556, "identity": "10.61%" }, { "cls_id": "homologset.agr.RGD:621142", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z220-1", "uniprot_id": "TSG10_RAT", "id": "Q9Z220-1", "name": "Testis-specific gene 10 protein", "aln": "-----------------------------------------MMR-NRSKSPRRPSPTSR---------AANCD--------VDLLKSTARDREELKCMLEKYERHLAEIQGNVKVLTSVRD-----------KTFLLYEQAQEEIARLRREMMKS------------------CQSPK--STTAHAILRRVETERD-----------------------------------VAFTDLRRMTTARDSLRERLKIAQ--AFNEKAHLEQRIEELECT-------VHNLDDERMEQMSNMTLMKETITIVEKEMKSLARKAMDTESELGRQKAENNS-LRLLYENTEKDLSDTQRH--LAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGATLNDLAKEKE------------------------------------------CLQTCLDKKSENIASLGESLAMKEK-TISGMKNIIAEMEQ-------ASRQSTEALIMCEQDISRMRRQLDETNDELGQIARERDILAHE------------------NDNLQEQFAKVKQENQALSKKLNDTHNELSDIKQKVQDTNLEVN----KLKNILKSEESTNLEVNKLKNILKSEESENRQIMEQLRKANEDAENWENKARQLEAENNTLKLELITAEAEGNRLKEKVDALNREVEQHLN-------AERSYKSQIATLHKSLVKMEEELQKVQFEKVSALADLSST-------RELCIKLDSSKE-------LLNRQLVAKDQEIEMMENELDSARSEIELLRSQMTNERISMQNLEALLVANRDKEYQS----------------------------------QIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERER--------------------AVQELRR---QNYSSNAYHLG-SMKPNTKCH----------SPERAHHRSPD---------------RDLDRSLEENLCYRDF----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NY15-1", "uniprot_id": "TSG10_MOUSE", "id": "Q6NY15-1", "name": "Testis-specific gene 10 protein", "aln": "-----------------------------------------MMR-NRSKSPRRPSPTSR---------AANCD--------VELLKSTARDREELKCMLEKYERHLAEIQGNVKVLTSERD-----------KTFLLYEQAQEEIARLRREMMKS------------------CKSPK--STTAHAILRRVETERD-----------------------------------VAFTDLRRMTTERDSLRERLKIAQETAFNEKAHLEQRIEELECT-------VHNLDDERMEQMANMTLMKETITTVEKEMKSLARKAMDTESELGRQKAENNS-LRLLYENTEKDLSDTQRH--LAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGATLNDLAKEKE------------------------------------------CLQACLDKKSENIASLGESLAMKEK-TISGMKNIIAEMEQ-------ASRQSTEALIMCEQDISRMRRQLDETNDELGQIARERDILAHE------------------NDNLQEQFAKVKQENQALSKKLNDTHNELSDIKQKVQDTNLEVN----KLKNILKSEE-----------------SENRQIMEQLRKANEDAENWENKARQTEAENNTLKLELITAEAEGNRLKEKVDALNREVEQHLN-------AERSYKSQIATLHKSLVKMEEELQKVQFEKVSALADLSST-------RELCIKLDSSKE-------LLNRQLVAKDQEIEMMENELDSARSEIELLRSQMTNERISMQNLEALLVANRDKEYQS----------------------------------QIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERER--------------------AVQELRR---QNYSSNAYNLG-PMKPNTKCH----------SPERAHHRSPD---------------RGLDRSLEENLCYRDF----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZW7-1", "uniprot_id": "TSG10_HUMAN", "id": "Q9BZW7-1", "name": "Testis-specific gene 10 protein", "aln": "-----------------------------------------MMR-SRSKSPRRPSPTAR---------GANCD--------VELLKTTTRDREELKCMLEKYERHLAEIQGNVKVLKSERD-----------KIFLLYEQAQEEITRLRREMMKS------------------CKSPK--STTAHAILRRVETERD-----------------------------------VAFTDLRRMTTERDSLRERLKIAQETAFNEKAHLEQRIEELECT-------VHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNS-LRLLYENTEKDLSDTQRH--LAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLNDLAKEKE------------------------------------------CLQACLDKKSENIASLGESLAMKEK-TISGMKNIIAEMEQ-------ASRQCTEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHD------------------NDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVN----KLKNILKSEE-----------------SENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLN-------AERSYKSQISTLHKSVVKMEEELQKVQFEKVSALADLSST-------RELCIKLDSSKE-------LLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEALLVANRDKEYQS----------------------------------QIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERER--------------------AVQELRR---QNYSSNAYHMSSTMKPNTKCH----------SPERAHHRSPD---------------RGLDRSLEENLCYRDF----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B704-1", "uniprot_id": "A0A8M2B704_DANRE", "id": "A0A8M2B704-1", "name": "", "aln": "-----------------------------------------MLRPRRSTSPVKGASTHRSPVRHSPVKGGSFD--------SELMR-VLRERDELQNMLDKHERHLSETQANVKVLTAERD-----------KTRMHYQQAQEEIAALRREVMKSKA----------------ARGAKSCSVTAQSILKRVETERD-----------------------------------EAISDLNRMTTERDSLRERLKISQETSISERAHLEQTLEDLQAA-------VLTLEQERGEQKCRHAQMRENMMGLEEEVHNLSRKLSASEEELIRCRNECCS-LRLSNNQMESSLSENQRR--LTNRIGELQNAQERNKTLDEMNDSLVRQVTVLREELNTQRATISQLDQQRN------------------------------------------TLQEQMEKKSDLINTANHQLDENEK-TIRSLKLRAEDLETTLIVLCSPSRALRDTISGKERELDVLKRKLSDSEKEMDTLMKVKDEASQE------------------NGQLRDDLDRAHQENQTLKFKLDEANLEIEDLQKKVQDHIADIS----RTEDLLSAKE-----------------RECRELQESRRKESILVESWEDQARRAETTVIELRLELHNANSEILRLKERADSLENRLQQALS-------AERSCTSQLSQLNRKMIHMEEDLCQARAEHTQAQADLEKT-------RELCVKLDASKD-------AVQR--------------ELESCCSEIELLQKQLTSERLSVQTLESLLVSTREKELQR----------------------------------QLTSQERQTEIEILKDKLSMADSKANSQSREMAQLKTRSCQLEADLEMTKRHLSTERFERER--------------------AVQELRR---QGLSAISPVLTSTMRSSSSSHRRSLSPHRSWSPEHSHLSTPDP--------------LLLSHYPDRNLTFRDLHD--------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MSL4-1", "uniprot_id": "M9MSL4_DROME", "id": "M9MSL4-1", "name": "", "aln": "MNINDGDFKDLRCKLDIMGFTQTLPVLAIPLVQAVFGDLIKTTECLRDTKKKVAELLEEKTCWELGVEPYKCDNSRLLAECNELHLQFLRDREDYELRLCESERKIRNLELDKQHLQSHNDGLQRQLDALLTKQMVSSVTNKKATAGIGRQTKKPFITTVRSGIAMPTTLGTSSSALKCTKCNAGVFQKTTTTTKDGVTVTQTSGQEELDKMQNDLTAAGEQLEFFKRKVEARNREIRRLNDMLAGGRPLAALAKDCCYKDVGALSQDIDLLQREKSDLMMQVREFQDKMHDAMQRALSSEEDKIKLQTQLEELKEAALQVEQQANAEIDAKESELRQLQLELKKKGKDHRLTGGFASNQSDKHNLNERLNLLTRREEELQATNEKHKKKIQKMQAKILELQKELKDQNKHSNVTLDEEKIRLSSERDFFQKEYLRLMSKTGSESEIAFLHAQIKSKDEELKALRSELFHGGKQQFSPQKSVQYETLPPPTASSITSTVTSNTSDCVQAAIARVERERDCARTELERVRCERDTLREKQLSTVQLHADELQALRLRNEELNDRLRQMERDNRELNSARLPTETNLVLLKEDLLQMRQRVASMQTEIDQLKTENDQITMLNDQNERIIADYQSKLLVAERQRQSADVRASTLDSSRESNRSEVTQLRMDLGALRQTYISLEHEKDTLLHQLDTKTERVYKLEYELKDCKEKRNALEQNVKDLEDQLRKLANRNRQRDSELTETSTESKTLRQQIVALKASRDEAIAENRRLMDKLSDAQVEARTLQKKLTDSELQVANMKQQLHKYVQEVKKAEDLLIQKVSSKFKEKERDDMLDQYHCLTQGQATLEGNNQSLECEAVEFRRQICELECEVHSLKEQLQLRQCALHDMEVQLTAARASVRCLERELENARDDIRVQKVDLEARKELCDKLDVERSKLNAELNDVNEIRKKLEKQCEKLRDELQQSLAINQVTNETTDLMLGRLHNDQQHQEDDDIRSKHEMDRLQRQLQQTLDQLQEERVRCRHHEELAEKWEQQVRDLRRNLADDRYNQARTREVSPRVPSKTL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *... . . * :* *:*:: : * : **:: : : : : * : .* * : :: : : *: *. . . * . .* : : . * :* ::.*:. . * ::: . .: . *.* :: *: * :::: : . .* :: ::..* . *.: * ** : :.. .: : ::.. : : :*: * . :.: ::::. ..: :* :: : *: :..*.: : : .* * : * : .* :: : : :.*: . :. *: : :* .. * :*.: : : .::*: *. :. :: :::.: : : . .:: . :: : .. :. . ... :.. . .: *:::* . *:.. *:* ..:: . :. ..: *.:.: .:*::* : .: . ::* .* *: : *.:*:: : :* .. :: ::.*: . .::. * **: . ..: : : * : *:. **::* : : . ::: : ** :*: :: .: .::.: * *:*:*: : . : .: . : :: * * *.: :..: *. ", "identical_positions": 79, "similar_positions": 272, "identity": "7.42%" }, { "cls_id": "homologset.agr.RGD:621143", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08943-1", "uniprot_id": "SSRP1_MOUSE", "id": "Q08943-1", "name": "FACT complex subunit SSRP1", "aln": "MAETLEFNDIFQEVKGSMNDGRLRLSRQGIIFKNSKTG--------KVDNIQAGELTEGIWRRVALGHGLKLLTKNGHVYKYDGFRESEFEKLSDFFKTHYRLELMEKDLCVKGWNWGTVKFGGQLLSFDIGDQPVFEIPLSNVS-QCTTGKNEVTLEFHQNDD----AEVSLMEVRFYVPPTQ----------------------------------EDGVDPVEAFAQNVLSKADVIQATGDAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEISFVNFARG---TTTTRSFDFEIETKQGT-QYTFSSIEREEYGKLFDFVNAKKLNIKNRGLKEGINPGYDDYADSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEEEDVAEEFDSNASAS------SSSNEGDSDREEKKREQLKRAKMAKDRKSRRKSSE---AKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARREYEKAMKEYEGGRGDSSKRDK---SKKKKKVKAKMEKKSTPSRGSSSK----SSSRQLS-DSFKSKEFVSSDESSSGENKSKKKRRR-SEDS-EEELASTPPSSEDSASGSDE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q04931-1", "uniprot_id": "SSRP1_RAT", "id": "Q04931-1", "name": "FACT complex subunit SSRP1", "aln": "MAETLEFNDIFQEVKGSMNDGRLRLSRQGIIFKNSKTG--------KVDNIQAGELTEGIWRRVALGHGLKLLTKNGHVYKYDGFRESEFEKLSDFFKTHYRLELMEKDLCVKGWNWGTVKFGGQLLSFDIGDQPVFEIPLSNVS-QCTTGKNEVTLEFHQNDD----AEVSLMEVRFYVPPTQ----------------------------------EDGVDPVEAFAQNVLSKADVIQATGDAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEISFVNFARG---TTTTRSFDFEIETKQGT-QYTFSSIEREEYGKLFDFVNAKKLNIKNRGLKEGINPGYDDYADSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEEEDVAEEFDSNASAS------SSSNEGDSDREEKKRKQLKRAKMAKDRKSRKKSSE---GKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARREYEKAMKEYEGGRGDSSKRDK---SKKKKKVKAKLEKKSTPSRGSSSK----SSSRQLS-DSFKSKEFVSSDESSSGENKSKKKRRR-SEDSDEEELASTPPSSEDSASGSDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08945-1", "uniprot_id": "SSRP1_HUMAN", "id": "Q08945-1", "name": "FACT complex subunit SSRP1", "aln": "MAETLEFNDVYQEVKGSMNDGRLRLSRQGIIFKNSKTG--------KVDNIQAGELTEGIWRRVALGHGLKLLTKNGHVYKYDGFRESEFEKLSDFFKTHYRLELMEKDLCVKGWNWGTVKFGGQLLSFDIGDQPVFEIPLSNVS-QCTTGKNEVTLEFHQNDD----AEVSLMEVRFYVPPTQ----------------------------------EDGVDPVEAFAQNVLSKADVIQATGDAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEISFVNFARG---TTTTRSFDFEIETKQGT-QYTFSSIEREEYGKLFDFVNAKKLNIKNRGLKEGMNPSYDEYADSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEEEDVAEEFDSNASAS------SSSNEGDSDRDEKKRKQLKKAKMAKDRKSRKKPVE---VKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARRDYEKAMKEYEGGRGESSKRDK---SKKKKKVKVKMEKKSTPSRGSSSK----SSSRQLS-ESFKSKEFVSSDESSSGENKSKKKRRR-SEDSEEEELASTPPSSEDSASGSDE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NLJ7-1", "uniprot_id": "F6NLJ7_DANRE", "id": "F6NLJ7-1", "name": "FACT complex subunit SSRP1", "aln": "MSDTLEFNEIYQEVKGSWNDGRLRFSKQTVVYKNSKTG--------KVDTIPVPELTQAQWRRVCLGHGIKLWTSTGHIYKYDGFKDADLEKISEYFKDNYKVELTEKDMCVKGWNWGTAKFNGPLLSFDVNDSPTFEIPLSSVS-QCTTGKNEVTVEFHQNDD----TEVSLMEVRFYVPPTTG---------------------------------DEGSDPVEAFAQNVLSKADVIQATGDAVCIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKEETISLTLNMNEDEVERRFEGKLNKNMSGSLYEMVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHLRFEEIACVNFARG---TTTTRSFDFEIETKQGN-QYTFSSIEREEYGKLFDFVNAKKLSIKNRGFKEGMKGNDDMYSDSDEDQHDAYLERMKEEGKIREE-GNDS-DDSEGESDESFNPGEEDEDIAEEYDSKASASE-----SSAEEGDSD-EDRKKKSAKKVKFVKERKPRKKE------KKVKDSGAPKRPMSAYMLWLNSSRDRIKSENPGISITEISKKAGEMWKQLGKDKKEEWDGKAEEAKKEYDRAMREYRESGGGSSGSSK---KERKKKRGRNEEKRKRKSGAGREK----EKERSTGNDSFKSREFISSEESSSESDKGKKRKRKGSDNEKEEEAVSTPASSE---SGSD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05344-1", "uniprot_id": "SSRP1_DROME", "id": "Q05344-1", "name": "FACT complex subunit Ssrp1", "aln": "MTDSLEYNDINAEVRGVLCSGRLKMTEQNIIFKNTKTG--------KVEQISAEDIDLINSQKFVGTWGLRVFTKGGVLHRFTGFRDSEHEKLGKFIKAAYSQEMVEKEMCVKGWNWGTARFMGSVLSFDKESKTIFEVPLSHVS-QCVTGKNEVTLEFHQNDD----APVGLLEMRFHIPAVE----------------------------------SAEEDPVDKFHQNVMSKASVISASGESIAIFREIQILTPRGRYDIKIFSTFFQLHGKTFDYKIPMDSVLRLFMLPHKDSRQMFFVLSLDPPIKQGQTRYHYLVLLFAPDEETTIELPFSEAELRDKYEGKLEKEISGPVYEVMGKVMKVLIGRKITGPGNFIGHSGTAAVGCSFKAAAGYLYPLERGFIYIHKPPLHIRFEEISSVNFARS---GGSTRSFDFEVTLKNGT-VHIFSSIEKEEYAKLFDYITQKKLHVSNMGKDKSGYKDVDFGDSDNENEPDAYLARLKAEAREKEEDDDDG-DSDEESTDEDFKPNENESDVAEEYDSNVESDSDDDSDASGGGGDSDGAKKKKEKKSEKKEKKEKKHKEKERTKKPSKKKKDSGKPKRATTAFMLWLNDTRESIKRENPGIKVTEIAKKGGEMWKELKD--KSKWEDAAAKDKQRYHDEMRNYKPEAGGDSDNEKGGKSSKKRKTEPSPSKKANTSGSGFKSKEYISDDDSTSSDDEKDNEPAKKKSKPPSDGDAKKKKAK-SESEPEESEEDSNASDEDEEDEASD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04636-1", "uniprot_id": "POB3_YEAST", "id": "Q04636-1", "name": "FACT complex subunit POB3", "aln": "--MSTDFDRIYLNQS--KFSGRFRIADSGLGWKISTSGGSAANQARKPFLLPATELSTVQWSRGCRGYDLKINTKNQGVIQLDGFSQDDYNLIKNDFHRRFNIQVEQREHSLRGWNWGKTDLARNEMVFALNGKPTFEIPYARINNTNLTSKNEVGIEFNIQDEEYQPAGDELVEMRFYIPGVIQTNVDENMTKKEESSNEVVPKKEDGAEGEDVQMAVEEKSMAEAFYEELKEKADIGEVAGDAIVSFQDVFFTTPRGRYDIDIYKNSIRLRGKTYEYKLQHRQIQRIVSLPKADDIHHLLVLAIEPPLRQGQTTYPFLVLQFQKDEETEVQLNLEDEDYEENYKDKLKKQYDAKTHIVLSHVLKGLTDRRVIVPGEYKSKYDQCAVSCSFKANEGYLYPLDNAFFFLTKPTLYIPFSDVSMVNISRAGQTSTSSRTFDLEVVLRSNRGSTTFANISKEEQQLLEQFLKSKNLRVKNEDREVQERLQTALGSDSDEED---------------INMGSAGEDDESVDEDFQVSSDNDADEVAEEFDSDAALS--------DAEGGSDEERPSKKPKVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: : : .**:::: . : :* :.:* * : . :: : .::: *. : : ** : : : : . :: : :: ::: .::*****.. : : * ... **:* : :. *.**** :**: :*: : *:*:**::* . . .: * ::: .**.: ..:*::: *::: ******** *: . ::*:***::**: : *:. **: *. : ::*::::**::**** * :*:* * :* : * :.: : . .::.:* *: .. : ::.:*:* * .*:: **:: .: . .: **:** * ****:..*::: **.::: *.::: **::*. ::*:**:*: :.. *:.*.:** * :::. *:* :.* . . ..:*:: : . . *.. . * .....:: .::***:**.. . *.** .:: . ", "identical_positions": 114, "similar_positions": 209, "identity": "14.65%" }, { "cls_id": "homologset.agr.RGD:621144", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55258-1", "uniprot_id": "RAB8A_MOUSE", "id": "P55258-1", "name": "Ras-related protein Rab-8A", "aln": "------------MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSSHGVKITVEQQKRTSFFRCSLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35280-1", "uniprot_id": "RAB8A_RAT", "id": "P35280-1", "name": "Ras-related protein Rab-8A", "aln": "------------MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSSHGVKITVEQQKRTSFFRCSLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61006-1", "uniprot_id": "RAB8A_HUMAN", "id": "P61006-1", "name": "Ras-related protein Rab-8A", "aln": "------------MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSNQGVKITPDQQKRSSFFRCVLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O18338-1", "uniprot_id": "O18338_DROME", "id": "O18338-1", "name": "", "aln": "------------MAKTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPKGGHQLKPMDSRTKDSWLSRCSLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07560-1", "uniprot_id": "SEC4_YEAST", "id": "P07560-1", "name": "Ras-related protein SEC4", "aln": "MSGLRTVSASSGNGKSYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDMET-RVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSNKLVGVGNGKEGNISIN-SGSGNSSKSNCC--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:** ::*:**********:*:*.** ** **.:**:********:*::::.*::***:***********************:****:*:*::* **::*::.::*:*. :.: :::***.:: * *: ::** ** : ** *:*:*** . **:: *:*** *: * :.. . :. . : .* ", "identical_positions": 97, "similar_positions": 63, "identity": "44.29%" }, { "cls_id": "homologset.agr.RGD:621145", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CJ53-1", "uniprot_id": "CIP4_MOUSE", "id": "Q8CJ53-1", "name": "Cdc42-interacting protein 4", "aln": "----------------------------------------------------------------MDWGTELWDQFEVLERHTQWGLDLLDKYVKFVKERAEVEQAYAKQLRSLVKKYLPKRPTKDDPE------------VKFSQQQSFVQLLQEVNDFAGQRELVAESLGIRVCLELAKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAHTAERLDQDINATKADVEKAKQQAHLRNHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELQVVPIIGKCLEGMKVAAESVDAKNDSQVLIELHKS--------------------GFARPGDLEFEDFSQVINRVPSDS-SLGTP-DGRPELRAASSRSRAKRWP-----FGKKNKPRPPSLSLLGGHLPSTLSDGPSSPRSGRDPLAILSEISKSVKPRLASFRSFRGGRGTVATEDFSHLPPEQQRKRLQQQLEER------NRELQKEEDQREALKKMKD-VYEKTPQMGDPASLEPRIAETLGNIERLKLEVQKYEAWLAEAESRVLSN-----------RGDSLSRHAR------------PPDPPTTAPPDSSSSSTNSGSQDNKESSSEEPPSEGQDTPIYTEFDEDF------------------EEPASPIGQCVAIYHFEGSSEGTVSMSEGEDLSLMEEDKGDGWTRVRRKQG----AEGYVPTSYLRVTLN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97531-1", "uniprot_id": "CIP4_RAT", "id": "P97531-1", "name": "Cdc42-interacting protein 4", "aln": "----------------------------------------------------------------MDWGTELWDQFEVLERHTQWGLDLLDKYVKFVKERVEVEQSYAKQLRSLVKKYLPKRPAKDDPE------------IKFSQQQSFVQLLQEVNDFAGQRELVAESLGIRVCLELAKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAHTAERLDQDINATKADVEKAKQQAHLRNHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELQVVPIIGKCLEGMKVAAESVDAKNDSKVLIELHKS--------------------GFARPGDLEFEDFSQVMNRVPSDS-SLGTP-DGRPELRAASSRSRAKRWP-----FGKKNK--------------------------------------------------------TVVTEDFSHLPPEQQRKRLQQQLEER------NRELQKEEDQREALKKMKD-VYEKTPQMGDPASLEPRIAETLGNIERLKLEVQKYEAWLAEAESRVLSN-----------RGDSLSRHTR------------PPDPPTTAPPDSSSSSNNSGSQDNKESSEEPPSEEGQDTPIYTEFDEDF------------------EEPASPIGQCVAIYHFEGSSEGTVSMSEGEDLSLMEEDKGDGWTRVRRKQG----GEGYVPTSYLRVTLN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15642-1", "uniprot_id": "CIP4_HUMAN", "id": "Q15642-1", "name": "Cdc42-interacting protein 4", "aln": "----------------------------------------------------------------MDWGTELWDQFEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPE------------SKFSQQQSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRSHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCLEGMKVAANAVDPKNDSHVLIELHKS--------------------GFARPGDVEFEDFSQPMNRAPSDS-SLGTPSDGRPELRGPG-RSRTKRWP-----FGKKNKPRPPPLSPLGGPVPSALPNGPPSPRSGRDPLAILSEISKSVKPRLASFRSLRGSRGTVVTEDFSHLPPEQQRKRLQQQLEER------SRELQKEVDQREALKKMKD-VYEKTPQMGDPASLEPQIAETLSNIERLKLEVQKYEAWLAEAESRVLSN-----------RGDSLSRHAR------------PPDPPASAPPDSSS---NSASQDTKESSEEPPSEESQDTPIYTEFDEDFE-----------------EEPTSPIGHCVAIYHFEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEG----GEGYVPTSYLRVTLN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3Q6-1", "uniprot_id": "CIP4_DANRE", "id": "Q5U3Q6-1", "name": "Cdc42-interacting protein 4 homolog", "aln": "----------------------------------------------------------------MDWGTELWDQYDILDKHTQSGLDLVDKYMKFVKERTDIEQNYAKQLRNLTKKYSPKRGSKEEQE------------CRFSNHQAFLDILNEMNDYAGQRELIAENMMINICVELNKYLQELKQERKMHLSEAKKSQQSLEAMYKQLDNSKKRFEREWREAEKAAQYADKTDQDLNATKADVEKAKQQAHLRTHIAEDCKNDYAAQLQKYNKGQSQFYFTDMPQIFNKLQDMDERRIKKMAQGYILFADTERHVMPIIGKCLEGMTRAGTNVNARNDSMVLIEQHKS--------------------GFERPGDLDFEDYSQGINRASSDS-SLGTP-KGPLELLGKN-KNKTFRL------FNKKSKFTPEK---------------------------------------------------PVDTEGFTHLPPEQRRKRLQQKIDDM------SKELQKEMDQSEALGKMKD-VYEKNPQMGDPASLAPQIGQTAQNMDRLRGELNKYESWLAEAGG----------------RGDSIRYSTH------------SINNNGAHNPNSHDGSCTLFSPG-ALSDETDPSQ-----AIYTEFDDEFEE----------------EELATPIGQCTALYNFPGSSEGTISMQEGEVLAVVEEDKGDGWTRVRRNNG----DEGYIPTSYATITLNK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JNK4-1", "uniprot_id": "A8JNK4_DROME", "id": "A8JNK4-1", "name": "", "aln": "MLKKKLAQITKKKTVADLEAECVHSAIAFTCVRVCAKLLASGSSRSSSNNKLAESENSAQNSNNMSWGTELWDQNENLAIHTNRGIDALDKFANFLRDRVAIETEYAGKLRRLVKNYQPKK--KEEED------------NEFTSVQAFRNLLKEVGDLAGQREVVSESLQLQIIAGVTLLSKTLREERKKCLSDGATLQQNLTTQLSSLDRAKRNYEKAYRDSEKAVDSYKRADMDLNLSRAEVERYKNVMTSKIQQSDDAKNEYANQLQKTNNLQQQHYSMLLPSVLNRLQELDEKRTRGFREFIVGAADVESSVAPIIARCMEGIVKAGESINEKEDTFKVIERYQS--------------------GFTPPRDIPFEDLSKCDPDSVQDS-HYSNSTSNHLTIRGTMSANKLKKRVGIFNIFGSNKNSLTAD----------------------------------------------------GQKEDFSDLPPNQRRKKLQAKIAEL------TQNIAQETKARDGLMKMKI-VYEANSSLGNPMTVEGQLNESEHKLEKLKVDLKKYQGFLEKASQVPTATSSPQASRNQLQNGHRTSRHSNGSADDHHDDGDDQPDDAGSLSRSDSEDNVAQIQNGHNNNNNGSASPESGLGTSHTSLPGSGQGSANENAIGEDTYYETEVETLNPVGKCRALYPFEASSEGSIPMSEGEELQVIEIDQGDGWTRVRRENNSNGWDEGFVPTSYIEITLYA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38822-1", "uniprot_id": "BZZ1_YEAST", "id": "P38822-1", "name": "Protein BZZ1", "aln": "------------------------------------------------------------MSADLSIGNEIKDSFKETHKWVQNNLKWLKDIEQFYRERAKLEKDYSERLSRLSAEYFNKKSSTSVPISVGDTPTTTPGSIEAAGVVAWNEILSQTDMISKDHDQLSTDFENHVANQLSGLFTKLDMTLSKINGFNNDMVNKKDNIYHELEKAKKDYDEACSTMEMARN---------RYTKASNDRNKKKLDEKEMEMNKCKNEYLIKINQANRTKDKYYFQDVPEVLDLLQDVNEAKTLFLNDLWLKAASVENDLGANVSKRLQAANSVVKQNKPSLNTAIFIKHNLKNWKEPQDFVYKPSPVWHDDEKFAVPSSLEVEDLRIKLAKAENDYNSLQDKTQNELSKLSTLNKIKHEMKTNEDNINATKFYDTLKEYLN---------------------------------------------VVSPFTSHETLKLQAEVQIESIQNNVPEEYDLSTDNIDLSKTKKKSGIFSKFKHNILNVDSKPSSGGSTGNGNGGPLHITSLFNTSRRTRLGSAPNNAGEDSDNNSIRTTSTNNTKKTTQNSSDDGKNKVLYAYVQKDDDEITITPGDKISLVARDTGSGWTKINNDTTGETGLVPTTYIRISSAATVKANDR--GPAPEVPPPRRSTLPVRTMEAIYAYEAQGDDEISIDPGDIITVIRGDDGSGWTYG-ECDG----LKGLFPTSYCK-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *.*: *. . .: .:. :. :* ::*. :* *: :* * :* *: .. . : :: ::*.: . : ::: :: .: .: : : . :. .*:.:*: ::. * * . . ::*. :: *: : :..**:* :::: *. : :.* :*.::: **:::* : : :..* : . :.: ::. . . :: .*: . * * .: .** .* .. . : .: .. .* .: : : :* :: : . :: : . : *:* : : .. .. : . . :. . .. . : . : .. . . .. . . : : . *: *:* : ...:. :.: *: : ::. *.*.*** . :. :* .**** ", "identical_positions": 52, "similar_positions": 185, "identity": "6.85%" }, { "cls_id": "homologset.agr.RGD:621146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKR6-1", "uniprot_id": "HYOU1_MOUSE", "id": "Q9JKR6-1", "name": "Hypoxia up-regulated protein 1", "aln": "MAATVRRQRPRRLLCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVTVTLKEN-----------ERFLGDSAAGMAIKNPKATLRYFQHLLGKQADNPH-VALYRSRFPEHELIVDPQRQTVRFQISPQLQFSPEEVLGMVLNYSRSLAEDFAEQP-------IKDAVITVPAFFNQAERRAVLQAARMAG-LKVLQLINDNTATALSYGVFRRKDINSTAQNVMFYDMGSGSTVCTIVTYQTVKTKEA-GMQPQLQIRGVGFDRTLGGLEMELRLREHLAKLFNEQRKGQKAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFDRVPGPVQQALQSAE----MSLDQIEQVILVGGATRVPKVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVIYPILVEFTREVEEEPGLRSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGESFKKYPD--YESKGIKAHFNLDESGVLSLDRVESVFET-LVEDSPEEESTLTKLGNTISSLFGGGTSSDAKENGTDAVQEEEESPAEGSKDEPAEQGELKEEAEPPAEETSQPPPSEPKGDAAREGEKPDEKESGDKPEAQKPNEKGQAGPEGAAPAPEEDKKPKPARKQKMVEEIGVELAVLDLPDLPEDELARSVQKLEELTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSATSTWLEDEGFGATTVMLKDKLAELRKLCQGLFFRVEERRKWPERLSALDNLLNHSSIFLKGAR-LIPEMD---QVFTEVEMTTLEKVINDTWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR-----EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASAGDQEEKVIPPAG--QTEEAKPILEPDKEETGTEPADSEPLELGGPGAGPEQEEQSAGQKRP-SKNDEL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63617-1", "uniprot_id": "HYOU1_RAT", "id": "Q63617-1", "name": "Hypoxia up-regulated protein 1", "aln": "MAATVRRQRPRRLLCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVTVTLKEN-----------ERFLGDSAAGMAIKNPKATLRYFQHLLGKQADNPH-VALYRSRFPEHELNVDPQRQTVRFQISPQLQFSPEEVLGMVLNYSRSLAEDFAEQP-------IKDAVITVPAFFNQAERRAVLQAARMAG-LKVLQLINDNTATALSYGVFRRKDINSTAQNIMFYDMGSGSTVCTIVTYQTVKTKEA-GTQPQLQIRGVGFDRTLGGLEMELRLREHLAKLFNEQRKGQKAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFDRVPGPVQQALQSAE----MSLDQIEQVILVGGPTRVPKVQEVLLKPVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVIYPILVEFTREVEEEPGLRSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGESFKKYPD--YESKGIKAHFNLDESGVLSLDRVESVFET-LVEDSPEEESTLTKLGNTISSLFGGGTSSDAKENGTDAVQEEEESPAEGSKDEPAEQGELKEEAEAPMEDTSQPPPSEPKGDAAREGETPDEKESGDKSEAQKPNEKGQAGPEGVPPAPEEEKKQKPARKQKMVEEIGVELAVLDLPDLPEDELAHSVQKLEDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSATSTWLEDEGFGATTVMLKDKLAELRKLCQGLFFRVEERRKWPERLSALDNLLNHSSIFLKGAR-LIPEMD---QIFTDVEMTTLEKVINDTWTWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR-----EVQYLLNKAKFTKPRPRPKDKNGTRTEPPLNASAGDQEEKVIPPTG--QTEEAKAILEPDKEGLGTEAADSEPLELGGPGAESEQAEQTAGQKRP-LKNDEL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y4L1-1", "uniprot_id": "HYOU1_HUMAN", "id": "Q9Y4L1-1", "name": "Hypoxia up-regulated protein 1", "aln": "MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKEN-----------ERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPH-VALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQP-------IKDAVITVPVFFNQAERRAVLQAARMAG-LKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEA-GMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAE----MSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPD--YESKGIKAHFNLDESGVLSLDRVESVFET-LVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR-LIPEMD---QIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR-----EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAG--QTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRP-LKNDEL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUW2-1", "uniprot_id": "HYOU1_DANRE", "id": "Q7ZUW2-1", "name": "Hypoxia up-regulated protein 1", "aln": "--------MREKLSLWAIFCLVVAFLPSQTESVAVMSVDLGSEWMKVAIVKPGVPMEIVLNKESRRKTPVAVCLKEN-----------ERLFGDGALGVAVKNPKVVYRFLQSILGKTADNPQ-VAEYQKHFPEHQLQKDEKRGTVYFKFSEEMQYTPEELLGMILNYSRTLAQDFAEQP-------IKDAVITVPAYFNQAERRAVLQAAHIAG-LKVLQLINDNTAVALNYGVFRRKDINSTAQNIMFYDMGSGSTTATIVTYQTVKTKES-GTQPQLQIRGVGFDRTLGGFEMELRLRDHLAKLFNEQKKSK--KDVRDNLRAMAKLLKEAQRLKTVLSANAEHTAQIEGLMDDIDFKAKVTRSEFEALCEDLFDRVPGPVKQALAAAE----MSMDEIEQVILVGGATRVPKVQDVLLKSVGKEELSKNINADEAAAMGAVYQAAALSKAFKVKPFLVRDAAVFPIQVEFSRETEEEDGVKSLKHNKRILFQRMAPYPQRKVITFNRYIDDFVFYINYGDLSFLSEQDMKVFGSQNLTTVKLSGVGSSFKKHSD--AESKGIKAHFNMDESGVLILDRVESVFET-IVEEK-EEESTLTKLGNTISSLFGGGSS-EPSANVTEPVTDEEEVTPEAGKEQ--DQPEKQEETVQEKPETEEGKEAEPQAEEQKEDKEKAENQGETESEKTEKPEEKTTDEE-----KEADMKPKLQKKSKISADIAVELEVNDVLDPSAEDMEGSKKKLQDLTDRDLEKQEREKTLNSLEAFIFETQDKLYQDEYQAVVTEEEKEQISGRLSVASSWMDEEGYRAGTKLLKEKLSELKKLCKGMFFRVEERKKWPDRLAALDSMLNHSNIFLKSAR-LIPESD---QIFTDVELKTLEKVINETITWKNETVAEQEKLSPTVKPVLLSKDIEAKLSLLDR-----EVNYLLNKAKFAKPKPKDKAKDKNSTSESSKANSTDDAEKVIPPK---TEDGAEKVKPAEEPPVVEEKAEETILELNPAENTDDKTESTESSKSENHIEDEL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46067-1", "uniprot_id": "O46067_DROME", "id": "O46067-1", "name": "Hypoxia up-regulated protein 1", "aln": "------------MKLVLLLSALLAG-IALSQGAAVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDG-----------TRTIGEDAQTIGIKDPNSAYGYLLDLLGKTIDNPI-VDLYRKRFPYYNIVGDPERNTVVFRKSDTDEFSVEELVAQLLVKAKQFAQESVQQP-------ITECVLTVPGYFGQAEREALLSAAQLAN-LKVLQLINDYAAVALNYGVFHRGEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNALKKTK--TDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCEDLWPRATKPLEEALASSH----LSLDVINQVILFGGGTRVPRVQET-IKAVIKQELGKNLNADESATMGAVYKAADLSAGFKVKKFVVKDATLFPLQVSFERDPGDG---AAVKQVKRALFALMNPYPQKKVITFNKHTDDFEFYVNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELVDNKGIKAYFYLDDSGIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFT-------KEG------EEKKDNSE------------QEEAANAGEEPSKS-----------EDNEKAKEEDASKEQKSEESTK-----------QDTEAKNETIKLVTVKSPVTYESQTQFVVPLVGSAYDQSVAKLAAINKAEEQRVRLESAFNALEAHIIEVQQKLDEESYAKCATAEEKEKLLAECSTLGEWLYEDLEDPKAEIYEEKLAQLKKLSNVFLARHWEHEERPEAIKALKGMIDGAEKFLVTGRNLTKDTNPEKDVFTQVEIDTLDKVITETNAWLKTETAAQKKLAKNADIRLTVKDITDKMSLLDR-----EVKYLVNKIKIWKPKVKPAAEKEKKKEEEVVASGSGDDTK---------SEDAE---QQQEQATKEEQQEQEPVDEITPTPAEEETKTPHSEL-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36016-1", "uniprot_id": "LHS1_YEAST", "id": "P36016-1", "name": "Heat shock protein 70 homolog LHS1", "aln": "-------------MRNVLRLLFLTAFVAIGSLAAVLGVDYGQQNIKAIVVSPQAPLELVLTPEAKRKEISGLSIKRLPGYGKDDPNGIERIYGSAVGSLATRFPQNTLLHLKPLLGKSLEDETTVTLYSKQHPGLEMVSTN-RSTIAFLVD-NVEYPLEELVAMNVQEIANRANSLLKDRDARTEDFVNKMSFTIPDFFDQHQRKALLDASSITTGIEETYLVSEGMSVAVNFVLKQRQFPPGEQQHYIVYDMGSGSIKASMFSILQPEDTTQ---PVTIEFEGYGYNPHLGGAKFTMDIGSLIENKFLETHPAIRTDELHANPKALAKINQAAEKAKLILSANSEASINIESLINDIDFRTSITRQEFEEFIADSLLDIVKPINDAVTKQFGGYGTNLPEINGVILAGGSSRIPIVQDQLIKLVSEEKVLRNVNADESAVNGVVMRGIKLSNSFKTKPLNVVDRSVNTYSFKLSNE-----------SELYDVFTRGSAYPNKTSILTN----TTDSIPNNFTIDLFENG--KLFETITVNSGAIKNSYSSDKCSSG-----VAYNITFDLSSDRLFSIQEVNCICQS---ENDIGNSKQIKNKG----------------------------------------------------------------------------------------------------------------------SRLAFTSEDVEIKRLSPSERSRLHEHIKLLDKQDKERFQFQENLNVLESNLYDARNLLMDDEVMQNGPKSQVEELSEMVKVYLDWLEDASFDTDPEDIVSRIREIGILKKKIELYMDS-AKEPLNSQQFKGMLEEGHKLLQAIETHKNTVEEFLSQFETEFADTIDNVREEFKKIKQPAYVSKALSTWEETLTSFKNSISEIEKFLAKNLFGEDLREHLFEIKLQFDMYRTKLEEKLRLIKSGDESRLNEIKKLHLRNFRLQKRKEEKLKRKLEQEKSRNNNETESTVINSADDKTTIVNDKTTESNPSSEEDILHDEL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:: : . **:.** *.: :*. :*.* .*:*:.*. *::** : :: * *. . :. : *: . .: :*** :: * * :.* :: * *: * . ::. **::. : *:. :: :.. :*:* :*.* :*.*:*.*: :: :: *:.: :.*:.: : :* * :.****: . .::.: : . ::. * *:: *** :: : : . : * : :: . :*:**: : * : * :****:: :**.*::*:**: :** ::* : * *:::*: .: *: *** ** :*:* **: :* * :::: :*:****:*. *.* :. ** .**.* : * * : . ..: .: :* .**::. * * * :. : : .:.. :. . : . : * :... :: *: : :. *:. :.. :.: * : : . :: : : :: . :. * **: : :.:: * : . . .: *:: .. *: : . . .:: :: * : : . : * :..::: . :* . : . * *:::* : : . : . :.* * : ::. : : *: : :. . .: * : : : : . : . ", "identical_positions": 125, "similar_positions": 273, "identity": "11.98%" }, { "cls_id": "homologset.agr.RGD:621147", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P27931-1", "uniprot_id": "IL1R2_MOUSE", "id": "P27931-1", "name": "Interleukin-1 receptor type 2", "aln": "MFILLVLVTGVSAFTTPTVVHTGKVSESPITSEKPTVHGDNCQFRGREFKSELRLEGEPVVLRCPLAPHSDISSSS-HSFLTWSKLDSSQLIPRDE-PRMWVKGNILWILPAVQQDSGTYICTFRNASHCEQMSVELKVFKNTEASLPHVSYLQISALSTTGLLVCPDLKEFISSNADGKIQWYKGAILLDKGNKEFLSAGDPTRLLISNTSMDDAGYYRCVMTFTYNGQEYNITRNIELRVKGTTTEPIPVIISPLETIPASLGSRLIVPCKVFLGTGTSSNTIVWWLANSTFISAAYPRGRVTEGLHHQYSENDENYVEVSLIFDPVTREDLHTDFKCVASNPRSSQSLHTTVKEVSSTFSWSIALAPLSLIILVVGAIWMRRRCKRRAGKTYGLTKLRTDNQDFPSSPN------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43303-1", "uniprot_id": "IL1R2_RAT", "id": "P43303-1", "name": "Interleukin-1 receptor type 2", "aln": "MFILLVLVTGVSAFTTPAVVHTGRVSESPVTSEKHPVLGDDCWFRGRDFKSELRLEGEPVVLRCPLVPHSDTSSSS-RSLLTWSKSDSSQLIPGDE-PRMWVKDDTLWVLPAVQQDSGTYICTFRNASHCEQMSLELKVFKNTEASFPLVSYLQISALSSTGLLVCPDLKEFISSRTDGKIQWYKGSILLDKGNKKFLSAGDPTRLLISNTSMGDAGYYRCVMTFTYEGKEYNITRNIELRVKGITTEPIPVIISPLETIPASLGSRLIVPCKVFLGTGTSSNTIVWWMANSTFISVAYPRGRVTEGLHHQYSENDENYVEVSLIFDPVTKEDLNTDFKCVATNPRSFQSLHTTVKEVSSTFSWGIALAPLSLIILVVGAIWIRRRCKRQAGKTYGLTKLPTDNQDFPSSPNQIKEMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27930-1", "uniprot_id": "IL1R2_HUMAN", "id": "P27930-1", "name": "Interleukin-1 receptor type 2", "aln": "MLRLYVLVMGVSAFTLQPAAHTGAAR--------------SCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRNASYCDKMSIELRVFENTDAFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEGQQYNITRSIELRIKKKKEETIPVIISPLKTISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTHIESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSFQTLRTTVKEASSTFSWGIVLAPLSLAFLVLGGIWMHRRCKHRTGKADGLTVLWPHHQDFQSYPK------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * *** ****** ...*** . .* ****.:* *:*******.**** .*: :* * : *** * **:: :* :* .***.:.. **:***:*:*****:** ****:*::**:**:**:**:* :* :** ** :**::*:******.** ..:* ******.::****.*::***. ..*:**: :.:: ********:**:::*::*****.****:* . *.********:**.******* :**********. .*::** **.*.*. *** ****** :::****:***:**.*******:***: *****. *. * *:*:*****.******.*.****** :**:*.**::****:::**: *** * ..:*** * *: ", "identical_positions": 238, "similar_positions": 107, "identity": "56.94%" }, { "cls_id": "homologset.agr.RGD:621148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6QGW5-1", "uniprot_id": "SRA1_RAT", "id": "Q6QGW5-1", "name": "Steroid receptor RNA activator 1", "aln": "MAELYVKPGNKERGWNDPPQFSYGLQTQTGGTKRTPLTKRVAAPQ----DGSPRAP--ETS-GPPPVDHPPPSSKASRPPPMGSCPASGVDPPSSPVIESETLIEDVLRPLEQALEDCRGHT-KQVCDDISRRLALLHEQWDGGKLSVPVKKRMALLVQELLHHQWDTADDIHRSLMVDHVTEVSQWMVGVKRLIAEKRSLSSEENK-EEKSTVAPE-NQTIPGFQPSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VJ2-1", "uniprot_id": "SRA1_MOUSE", "id": "Q80VJ2-1", "name": "Steroid receptor RNA activator 1", "aln": "MAELYVKPGNKERGWNDPPQFSYGLQTQTGGPKRTPLTKRVAAPQ----DGSPRAP--ETS-GPPPVDHPPPSSKASRPPPMGSCPATGVEPPSSPVIESETLIEDVLRPLEQALEDCHGHTKKQVCDDISRRLALLREQWAGGKLSIPVKKRMALLVQELLHHQWDAADDIHRSLMVDHVTEVSQWMVGVKRLIAEKKSLSSEETK-EEKFTVEPE-NQTIPGFQQPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HD15-1", "uniprot_id": "SRA1_HUMAN", "id": "Q9HD15-1", "name": "Steroid receptor RNA activator 1", "aln": "MAELYVKPGNKERGWNDPPQFSYGLQTQAGGPRRSLLTKRVAAPQ----DGSPRVPASETSPGPPPMGPPPPSSKAPRSPPVGSGPASGVEPTSFP-VESEAVMEDVLRPLEQALEDCRGHTRKQVCDDISRRLALLQEQWAGGKLSIPVKKRMALLVQELSSHRWDAADDIHRSLMVDHVTEVSQWMVGVKRLIAEKRSLFSEEAANEEKSAATAEKNHTIPGFQQAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BL77-1", "uniprot_id": "A0A8M2BL77_DANRE", "id": "A0A8M2BL77-1", "name": "Steroid receptor RNA activator 1", "aln": "MSDRFVKPGNQEHGWNDPPQFSYGLQKDSGGQKRNILNKRVHAPQTTAGSGSEIQSTPLAGQTPPRGINPPPMDGVTPPPACPRVPSDGAVEAVQS--ETEPRFEDVQESLYWALNACRPNVKKQVCDDVERRLKVFEDMWKTGKLSLLVKRRMLGLSQELKRKNWDAADEIHRGLMVDHVSEVSQWMVGVKRLIAEARSLKPEQIS-----------SCTDAGS----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: :*****:*:*************.::** :*. *.*** *** .** . :. ** *** . .. .*. *: *. . . *:*. :*** ..* **: *: :. ******:.*** ::.: * ****: **:** * *** :.**:**:***.******:*************** :** .*: . * .* ", "identical_positions": 104, "similar_positions": 52, "identity": "45.41%" }, { "cls_id": "homologset.agr.RGD:621149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VNX2-1", "uniprot_id": "Q9VNX2_DROME", "id": "Q9VNX2-1", "name": "", "aln": "-----------MAASEAPPADPAVEVAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECD-LPGSNYYEPHTNWSIP-----KNGKDLDSCNRYTN------SELPQWN-HSVDICSADHFTKNKEACAHNEFVFRDD--EVTISNDFGIFC-DDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRR-VLACSVITVFYAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANRDKLQ-QSSESR--------FPIREAFKNFK------WRIANCSLCWIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQ-------------------PVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAIGVKKQSKSKDLDLVVTATQAQ------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNW8-1", "uniprot_id": "Q9VNW8_DROME", "id": "Q9VNW8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "MTSQKEGNGYRRSDSKTTGHADAEAATQTAGGDEDNSLDAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCD-SPSSVYEEDWLGFTIP-----KKNSAWDDCHRYAAN---ISDAISGYTDPSGQYCLKEYFTITSETCGR-DFKFRDE--EKTISTEFGIYC-EDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSNYSMFLVFEFLDMAVGSTLFPTAFLLAIELVGPKRR-VAAATIITIFYALGEAFLGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLNDLLTSNRQKLS-QANESQ--------YPIMRAVVFFS------LRIANCCLCWFTHTLIALGLSLNSVNLGGNKYTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADN-------------------YAGSLALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGFLTLAFPETADKVLPTTIEEARDLNQAKRRSERSP----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4KFK6-1", "uniprot_id": "A0A0B4KFK6_DROME", "id": "A0A0B4KFK6-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-----------------------MSAPAAGAASAVLDFDDILVEIGEFGRFQRRNYLLICLPVLFAAANSLSYVFTAGSPTYRCYVPECDKLVDAEYGANWVSIAVPGSWSKRGHFTPSTCERFVANGDHLESSSDPWSAWPLDQCFAENFTTETERCNQ--FVYGSS--ERTIVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKR-EMSSIVLNYFYAVGEALLG-LSVFLPDWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVTLAQGDWIPCQTGVESRHSWSCANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEEAIALGK-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9R141-1", "uniprot_id": "S22A4_RAT", "id": "Q9R141-1", "name": "Solute carrier family 22 member 4", "aln": "----------------------------------MRDYDEVIAFLGDWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPHTVNLSSAWRNHSIPLETK------DGRQVPQSCRRYRLA------TIANFSALGLEPGLDVDLEQLEQESCLDGWEYSKDVFLSTIVTEWNLVC-EDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQIFSTNWEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRILFSTLGVCTFFAIGYMVLPLFAYFIRDWRMLLLALTLPGLFCVPLWWFIPESPRWLISQRRFEEAEQIIQKAAKMNGIMAPAVIFDPLELQELNSLKQQ----------------KVFILDLFKTRNIATITVMSVMLWMLTSVGYFALSLNVPNLHGDVYLNCFLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLVQVVPEDYN-------------------FVSIGLVMLGKFGVTSAFSMLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGIITLFFPESFGVTLPENLEQMQKVRGFRCGKKSTVSMDREENPKVLITAF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z306-1", "uniprot_id": "S22A4_MOUSE", "id": "Q9Z306-1", "name": "Solute carrier family 22 member 4", "aln": "----------------------------------MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPDTVNLSSSWRNHSIPLETK------DGRQVPQSCRRYRLA------TIANFSAMGLEPGQDVDLEQLEQESCLDGWEYDKDIFLSTIVTEWNLVC-EDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQIFSTNWEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRIIFSTLGVCTFFAIGYMVLPLFAYFIRDWRMLLLALTLPGLFCVPLWWFIPESPRWLISQRRFAEAEQIIQKAAKMNSIVAPAGIFDPLELQELNSLKQQ----------------KVIILDLFRTRNIATITVMAVMLWMLTSVGYFALSLNVPNLHGDVYLNCFLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLIQVVPEDYN-------------------FVSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGIITLFFPESFGVTLPENLEQMQKVRGFRCGKKSTVSVDREESPKVLITAF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H015-1", "uniprot_id": "S22A4_HUMAN", "id": "Q9H015-1", "name": "Solute carrier family 22 member 4", "aln": "----------------------------------MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSSAWRNNSVPLRLR------DGREVPHSCSRYRLA------TIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYLSTVVTEWNLVC-EDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFD--SVEELNPLKQQ----------------KAFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVLLFIQLVPVDYY-------------------FLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQKVKWFRSGKKTRDSMETEENPKVLITAF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PJE3-1", "uniprot_id": "A0A8M9PJE3_DANRE", "id": "A0A8M9PJE3-1", "name": "", "aln": "----------------------------------MGNYDEDTAFLGQTGPFFIRLFCLLNLIYISTGLHGLYIVFVAASPAHRCRV--DVNLTEDWLEASAPTETLS-----NGDLQVSQCWRYSLQ------TLTNLSGQGYSPGQ-INITDIPRERCEDGWVYSADVYHSTIVSEWDLVC-DSEWRVPLASSTLYMGYLLGSIVSGQLSDRFGRKKVLFGSLAAEALLMFAQSFSPSWLIFCVLYFFIGAFQISLYITAFVLGNEVLSGSLRVLFTTLGAFLHYCVGYMLLPWVAFAIRHWRTLLRVLSGLTVVYIPLWWLIPESPRWLLSQGHVQESEAILRDAARKNRVPAPEVIFKQSQIKEA-AFQKS----------------KYSALDVLRTSNIRRTTFMCLLLWMAINIGYFGLSLNTTNLSGDPFLNCFLSAVTEVPAYIVSTFLLKSCPRRPVLSAFLVIGGGFLLLVQLIPDRLQ-------------------TLALALEMAGKFGFTMSFTVVYIYTAELYPTVLRNLGMGMCSSAARIGSITAPYIIFLGTFNRHLPYVLMGSLTITASLANLFLPETFGKVLPENLEQMQKSRSFP-GRDKQSVEDGGGGEKMREEKL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCA2-1", "uniprot_id": "ORCT_DROME", "id": "Q9VCA2-1", "name": "Organic cation transporter protein", "aln": "-----------------------------------MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNLSYP----------ENERCSYYDVD------YTEEYLN------GSIPRSSNETKTCSS-YVYDRSKYLNSAVTEWNLVC-SRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYR-LFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAAS---------QPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMN-------------------WLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGENFGKKPAPQETAEEGGTQELSGMLNGKSG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :*: * : : *: : . : ** .. .** : * : : : . : ::.: * . . : * . * : * .:*: ** : . .: .: : . : : .:::. *::. * : .:.:* . : . .** * :. : *::*** ***: : .: ::. **: * . . . : * .** : * *: * ::*. . : ** :.. :. . : : **: .* :: :* :::* ** :*. :. * .*.*.: ** *. * :: . :: .: .* :**: . :* .::: ", "identical_positions": 60, "similar_positions": 122, "identity": "9.43%" }, { "cls_id": "homologset.agr.RGD:621150", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08719-1", "uniprot_id": "EVL_RAT", "id": "O08719-1", "name": "Ena/VASP-like protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFAF---EEFSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN----SQEGGPSTQRQVQNGPS------PEEMDIQRR------QVMEQ--QHRQESLERRIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGPILPPGHPSSAASAT-------FSCSGPPPPP-----PPPVPPPPTGSTPPPPPPLPAGGAQGT---NHDESSASGLAAALAGAKLRRVQRPEDASGGSSPSGTSKSDANRAS---SGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDENQTEDPSTSPSPGSRATSQPPNSSEAGRKPWERSNSVEKPVSSLLSRTPSVAKSPEAKSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70429-1", "uniprot_id": "EVL_MOUSE", "id": "P70429-1", "name": "Ena/VASP-like protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASSTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN----SQEGGPSTQRQVQNGPS------PEEMDIQRR------QVMEQ--QHRQESLERRIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGPILPPGHPSSAASTT-------LSCSGPPPPP-----PPPVPPPPTGSTPPPPPPLPAGGAQGT---NHDESSASGLAAALAGAKLRRVQRPEDASGGSSPSGTSKSDANRAS---SGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDESQTEDPSTSPSPGTRATSQPPNSSEAGRKPWERSNSVEKPVSSLLSRTPSVAKSPEAKSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UI08-1", "uniprot_id": "EVL_HUMAN", "id": "Q9UI08-1", "name": "Ena/VASP-like protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN----SQEGGPSSQRQVQNGPS------PDEMDIQRR------QVMEQHQQQRQESLERRTS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGPILPPGHPSSAASAP-------VSCSGPPPPP-----PPPVPPPPTGATPPPPPPLPAGGAQGS---SHDESSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRAS---SGGGGGGLMEEMNKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B578-1", "uniprot_id": "A0A8M2B578_DANRE", "id": "A0A8M2B578-1", "name": "Ena/VASP-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAHSVQFCLPQSHSDSGLHTSG---CKISEQSICQARASVMIYDDTSKKWVPVKPGQQGFSRINIYHNTVNNSFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSTAMLFALNVLG----SQDAGPGAHR--QNGPV------TDDGEAQRR------QMMDQ--HQMQMERERRTSGSAVSTLQFKVSASASQSETSLHDLRQYRANTLPPSYAHLNPAASSAHTAIPPLQEGGYHMVDSPQKKAQQLSQLSTSLASAFSPVQQGVVPPPRNIKQIPLSPPTSQQDLKHATWSSAHMYAPLPAASPPVVMAVKQPGLPVALPLPPLNNGPKAPSNTSHLDPIMHLQQSSNGQAEECYPYQSPSGGPLHPHYPIQESSCPLPPLIGQPVQGPGLHPQQLYQTTPPFETTPTSHTTPKTSPSPVYQNAAAASTGPPVPPGHPSMLSAAPPVHPPTSASMVGPPAPP-----PPPGPPPPGPPPPGPPPPVTGPPPTPPPLPAGGGPAPSGLAAALAGAKLRKVQRPEESSSSSNNSSNSKNDASRSSGG-SGGGGEGLMQEMNALLARRRKAS---EKPED-----SQNEESNGSPS------SSRGQNSDPVKKPWERANSADK-----------------------SSAVSRAKPLGSTSDA--ESFDFDRMKQEILEEVVRELQKVKEEIIDAIRRELLRIGST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T4F7-4", "uniprot_id": "ENA_DROME", "id": "Q8T4F7-4", "name": "Protein enabled", "aln": "MAMKKLYAKTSFTSKKPSSAANSTPILAYHQQQHQQPGNGICEFQVVAPGHSGELMIRRSQSMHHKMSPPVGGLGSKSEYYSIEELQELDLLDYRHPMYHHYQQQELRQRYHEHEQLVLQLPKATSPKAGPIYEAPQRSQQQQDQMLYVPTAAQRDSSSSAAATSIASSSTLTSSPSPSSSSSLIFSTLRKCVSPSNPSVNPNQPSKTQPSKLGCSMSFSIRTTTATAATAAAANAATATLSTQQQQQQAQQQHKQHLYSNIHHYLIRQQQQKQHYTLQRRHNSVKDKFIGGITTIFAEQSIIGARASVMVYDDNQKKWVPSGS-SSGLSKVQIYHHQQNNTFRVVGRKLQDHEVVINCSILKGLKYNQATATFHQWRDSKFVYGLNFSSQNDAENFARAMMHALEVLSGRVANNPGGPPTNGNGYEEDMGYRTMTSEDAAILRQNNSIGGHVTPSAQTPTSQTNQNNIPQSPPTPQGHHRTSSAPPAPQPQQQQQQQQAQQMGQPGSHYGPTGNGPTSNGLPQQVNSQIPPAPQQQPQQQQFQQQQQQQQYQQMVQAGYAPSQQYQQPHYVLSNSNPNLTVHQYPTQQAQQQPPQAPQPPLQNGGMYMVGHGHLP-------SSASANSVVYASQQQMLPQAHPQAPQAPTMPGPGYGGPPVPPPQQQAENPYGQVPMPPPMNPSQQQQPGQVPLNRMSSQGGPGGPPAPAPPPPPPSFGGAAGGGPPPPAPPQMFNGAPPPPAMGGGPPPAPPAPPAMGGGPPPAPGGPGAPPPPPPPPGLGGAPKKE---DPQADLMGSLASQLQQIKLKKNKVTTSAPENSGSSTSSGGSGNYGTIGRSSNGMASMMDEMAKTLARRRAQAEKKDPDPEAEVKKRPWEKSNTLPHK-----LSGGAGSGSAGSGHEGANGNSGGAGSNTTNSGGESPRPMRKRFGSASEETILKVNGDGLSLALSNGDLDTLKAEIVREMRLEIQKVKNEIIDAIKSEFNRR---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::**** ******:***..***** . ..*:*:::***: ..:***** ****::**** **:*********.*******:: ******:*:::* .*: **:.**:::. .: .** :: : .:: *: :: . . :.. . : * **. *. .:. . .**.** *** * * ..* **** . . ..**: : **:: : . .:. .*. * .* .... .: *..* .:*:** **:** : : : *... * . .* . . * :*. . :. : * *. . . *:* :* **:.*: *::***:******: *: ", "identical_positions": 128, "similar_positions": 120, "identity": "12.81%" }, { "cls_id": "homologset.agr.RGD:621151", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VDA1-1", "uniprot_id": "CSTN2_RAT", "id": "Q8VDA1-1", "name": "Calsyntenin-2", "aln": "--MLPGRLCLVPLLLALGVGSGGGSGDGGDSRRRRLLAAKVNKHKPWIETSYHGVITENNDTVILDPTIVALDKDAPVPFAGEICAFKIHGQELPFEAVVLNKTSGEGRLRAKSPIDCELQKEYTFIIQAYDCGAGPQEAAWKKSHKAVVHIQVKDVNEFAPTFKEPAYKAIVTEGKIYDSILQVEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNGNIRNTEKLSYDKQRQYEILVTAYDCGQKPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPG-SGSMPLFPGIHLETCDGAVSS-----LQVTAELQTNYIGKGCDRETYSEKSLQKLCGASSGIIDLLPSPSAATNWTAGLLVDS---SEMIFKFDGRQGAKIPDGIVPKN--LTDQFTITMWMKHGPSPGVR-AEKETILCNSDKTEMNRHHYALYVHNCRLVFLLRKDFDQADT--FRPAEFHWKLDQICDKEWHYYVINVEFP-VVTLYMDGATYEP--------YLVTNDWPIHPSH-IAMQLTVGACWQGGEVAKPRFAQFFHGSLASLTIRPGKMESQKVISCLQACKEG------LDINSLESLGRGIKYHFNPSQSILVMEGDDIGNINQALQKVSYINSRQFPTAGVRRLRLSSKVQCFGEDVCISIPDVDAYIMVLQAIEPQ-------ITLQGTERFWRPAAQFESARG-----VTLFPDIKIISTFAKTEASGDLRATGTAPKSAVLEEMLHNLDFCDILVLGGDLDPRQECLELNHSELHQRHLDATN--STAGYSIYGVGSMSRYEQVLHHLRYRNWHPTSLETRRFQIKCSELNGRYTSNEFNLEVSVLHEVRVSDTEHVNHLIVQPPFLQSVYHPETRSSIQ--RSSVVPSIATVVIIISVCMLVFVVAMGVYRVRIAHQHFIQETEAAK-EAEMDWDDSALTITVNPMEKHEGPGHGEDE-TEGEEEEEAEE-------------------GMSSSSSGSDDSEEEEEEGMGRVRHGQSGTSSQRPERSTWNTAGVINIWK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER65-1", "uniprot_id": "CSTN2_MOUSE", "id": "Q9ER65-1", "name": "Calsyntenin-2", "aln": "--MLPGRLCLVPLLLALGVGSGGGSGDGGDSRRRRLLVAKVNKHKPWIETSYHGVITENNDTVILDPPLVALDKDAPVPFAGEICAFKIHGQELPFEAVVLNKTSGEGRLRAKSPIDCELQKEYTFIIQAYDCGAGPREAAWKKSHKAVVHIQVKDVNEFAPTFKEPAYKAIVTEGKIYDSILQVEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNGNIRNTEKLSYDKQHQYEILVTAYDCGQKPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPG-SGSMPLFPSIHLETCDGAVSS-----LQVTAELQTNYIGKGCDRETYSEKSLQKLCGASSGIIDLLPSPSAATNWTAGLLVDS---SEMIFKFDGRQGAKIPDGIVPKN--LTDQFTITMWMKHGPSPGVR-AEKETILCNSDKTEMNRHHYALYVHNCRLVFLLRKDFDQADT--FRPAEFHWKLDQICDKEWHYYVINVEFP-VVTLYMDGATYEP--------YLVTNDWPIHPSH-IAMQLTVGACWQGGEVAKPRFAQFFHGSLASLTIRPGKMESQKVISCLQACKEG------LDINSLESLGRGIKYHFNPSQSILVMEGDDIGNINRALQKVSYINSRQFPTAGVRRLRLSSKVQCFGEDVCISIPDVDAYIMVLQAIEPQ-------ITLQGTERFWRPAAQFESARG-----VTLFPDIKIVSTFAKTEASGDMRATGTAPKSAVLEEMLHNLDFCDILVLGGDLDPRQECLELNHSELHQRHLDATN--STAGYSIYGVGSMNRYEQVLHHLRYRNWHPTSLETRRFRIKCSELNGRYTSNEFNLEVSVLHEVRVSDKEHVNHLIVQPPFLQSVHHPETRSSIQ--RSSVVPSIATVVIIISVCMLVFVVAMGVYRVRIAHQHFIQETEAAK-EAEMDWDDSALTITVNPMEKHEGPGNGEDETTEVEEEEEAEE-------------------GSSSSSSGSDDSEEEEEEGMGRVRHGQSGTSSQSPERSTWNTAGVINIWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4D0-1", "uniprot_id": "CSTN2_HUMAN", "id": "Q9H4D0-1", "name": "Calsyntenin-2", "aln": "--MLPGRLCWVPLLLALGVGSG--SGGGGDSRQRRLLAAKVNKHKPWIETSYHGVITENNDTVILDPPLVALDKDAPVPFAGEICAFKIHGQELPFEAVVLNKTSGEGRLRAKSPIDCELQKEYTFIIQAYDCGAGPHETAWKKSHKAVVHIQVKDVNEFAPTFKEPAYKAVVTEGKIYDSILQVEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNGNIRNTEKLSYDKQHQYEILVTAYDCGQKPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPG-SGSMPLFPSIHLETCDGAVSS-----LQIVTELQTNYIGKGCDRETYSEKSLQKLCGASSGIIDLLPSPSAATNWTAGLLVDS---SEMIFKFDGRQGAKVPDGIVPKN--LTDQFTITMWMKHGPSPGVR-AEKETILCNSDKTEMNRHHYALYVHNCRLVFLLRKDFDQADT--FRPAEFHWKLDQICDKEWHYYVINVEFP-VVTLYMDGATYEP--------YLVTNDWPIHPSH-IAMQLTVGACWQGGEVTKPQFAQFFHGSLASLTIRPGKMESQKVISCLQACKEG------LDINSLESLGQGIKYHFNPSQSILVMEGDDIGNINRALQKVSYINSRQFPTAGVRRLKVSSKVQCFGEDVCISIPEVDAYVMVLQAIEPR-------ITLRGTDHFWRPAAQFESARG-----VTLFPDIKIVSTFAKTEAPGDVKTT--DPKSEVLEEMLHNLDFCDILVIGGDLDPRQECLELNHSELHQRHLDATN--STAGYSIYGVGSMSRYEQVLHHIRYRNWRPASLEARRFRIKCSELNGRYTSNEFNLEVSILHEDQVSDKEHVNHLIVQPPFLQSVHHPESRSSIQ--HSSVVPSIATVVIIISVCMLVFVVAMGVYRVRIAHQHFIQETEAAK-ESEMDWDDSALTITVNPMEKHEGPGHGEDE-TEGEEEEEAEE-------------------EMSSSSGSDDSEEEEEEEGMGRGRHGQNG---ARQAQLEWDDSTLPY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S5G3-1", "uniprot_id": "CSTN2_DANRE", "id": "B0S5G3-1", "name": "Calsyntenin-2", "aln": "---MKMRAITAMLLLVLSGQCG-------------ILAGKVNKHKPWIETSYHGVITENMDTVMLDPPLVALDKDAPVPYAGEICAFKIHGQEAPFEAEVLNRTSGEGVLRARGPIDCEQQKEYTFIIQAYDCGASPNGADWKKSHKAVVHIQVDDVNEFSPVFREPLYRATVTEGKIYDSILQVEAWDQDCSPQYSQICNYEIVTQDTPFAIDRNGNIRNTERLSFDKQQHYKIMVTAYDCGQKRAMESVPVHIDVKPVCKPGWQGWNKRVDYEPG-TGSKQLFPKMHLETCDGPLSS-----VRAMVELQTSHIGKGCDRETYSEKSLQKLCGAASGSTDLLPAPSTSTNWTASLLTDSGRDSDLIFRFDGRQAANIPDWVVPQN--LTDQFTIATWMKHGPSPGLR-AEKETLLCNSDKTEMNRHHYSLYVHNCRLVFLLRRDFIQLDS--FRPAEFHWRLEQICDKEWHYYVINVEFP-SVTLFVDGVTYEP--------YLVTDDWPIHPSE-IDVQLTVGACWQGGEVTTPRFTQYFRGSLSGLTIRPGKIATQKVISCLQACKEG------LDISSLESLGKGIKFHFNPAQSVLVMEADDLESINTAMTKVSYINSRQFPTPGLRKLHITTTVQCFGEDTCISIPEIKAMVMVLPPSEPR-------ITIAGVERLVWPSAQLRAPVG-----VALFKDIHIISTVTKTDATLSIARR------PGVLELMHNLDYCDVLVIGEELDPERESLEIHHSSLLGKHLDATN--STSGISIYGVDSMAHYEQAIRQVRYRNWKPGSLSERRFRLSCSELNGRYTSNEFNLEIGVVHSS--EAVEHVNHMAVQSQFMRPVHHPLVVHTVNSDHISGTPPAATVVIVMCIAALVVIVVLGIYRIHTTHQDSSKEDEEERKDPEMDWDNSNLN-SIEGTQIAEEVREEEPEEDEDEDEEDDDL-------------------AGDLSSAESEDSDEDEETNIQKG---------KVKGKLEWDPSTLPY---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V498-1", "uniprot_id": "CSTN1_DROME", "id": "Q9V498-1", "name": "Calsyntenin-1", "aln": "MTFHKTFGYGCIVLICFELLFAG------VETSSENDDEYLTQKEIILEKSYHGLIRENETLVEITPLIKVNEE--------KICNFHILKKPYHEIPFKIELVNNLGILKARRTLNCENRKSYHFEICAIYCDGTP-------SNTANVHITVIDVNEYAPTFLEPSYVIEVDEGRLYNEILRVEASDKDCTPLFGDVCKYEILNNDEPFSIDNEGSIKNTEPLSHKASHNHILSVVAYDCAMKESAP-IMVSIKVRRVCETKFVGMPERIDYTSGSTESLQLFPNARLDLCDISCKNEEDLRIHSSIALKTKHISFGCDRDISN-------CTSGQKVKDLLP---HGAEWTKELSYDEG--LEPIFHFDGSTGVVVPATVIDHYDFSSQPFSILTLFRHNSQVEINKHVKEHIVCSADDHKMNRHHMALFVRNCRLIFLLRKNFNEGDLNIFSPAEWRWKIPEVCDNEWHHYVLNVEDSSKVDLFIDGVRFENSIENRHSNPEVIDDWPLHAAHGVNTSLAIGACYQS---LENRLKHGFNGDISEVKVSLNSVLTAEDIKCGTTCAEHLLAPKPLQSNNEKSYSDNSQIKENIEMNEIYISAKNKHDIEQFMRKVQYINTKQKPTVGRRNIEVLTTLNCK-NESSLRLPPIETYIMVNEPIAPLGIDIDVVSASLETSDLTPPSYSPKIAISGTSNKLVSYQEIKLGVHILEKTCIDSVSKN------NGKLEEKNHIDSCSVVVFP-SLNPDHEDIKIDGDESLSSSMDIKTNINKDGVEMIGKDTISNYINVLRSLVYSNKKPAYYLNRVFKLSCAQQSSQYKSGEYTLTLTVLHPKQ-TLFKSTNVLPSSLSKVNFIGNTDNETSFHRNSGSVNGNDNNQPTESKVYSYSLLHTNNVQEPKSHIHSFIHKAEGSHVTMLIILVSVFLAVLLCGVSIARLKNNQKYIEHHQPCPKISDDGLIWDDSALTITINPMQADVTSDASSESENSESEDEEALKDG--------FTHINQLEWDNSNIFQQ--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: : . :.::: :*.****:* ** * : * : . :: :** *:* : . :: ... * *:*: .::** :*.* * * * *.. * *:.* *** * ****::*.* ** * * **::*:.**:*** *:**:* :.::*:***:. * **:**.:*.*:*** **.. .::: : *.****. * : * :.*: **:. : . :*::* .* : * *** :*: ** . .. :: *:*.:*. ****: . * :.. **** .::** * *. : **:*** .. :* :: : :: *:* ::*... :. ** ::*.:*. :***** :*:*:****:****::* : * * ***::*:: ::**:***:**:*** . * *::**. :* * :***:*.:. : .*::***:*. :: : *.*.:: :.: ..: : : *.* :* * *: .. :* . . : : * . : :...: .*: : **.***::* ** * *.:.: :.::* :: .: :* :.: :** . * : .. : *: . . . . :. : :*:: . :. . .: * :::* *.::*: .*:* :* :::. .. :* .. .. * .: * .:: .* :.:: : * * :* * *::.*:: ..:*.*.*:.* : ::* : .* : . :. : :. :.: * . : .: . .: . : : :: * : : . * : . . . : . : : . :*. .:..:.::* : : *: : : ", "identical_positions": 223, "similar_positions": 333, "identity": "21.57%" }, { "cls_id": "homologset.agr.RGD:621152", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02862-1", "uniprot_id": "CS2LA_MOUSE", "id": "Q02862-1", "name": "Alpha-S2-casein-like A", "aln": "MKFFIFACLVVVALAKHEIKDKSSSEESSASIYPGKSKLDNSVFFQTTKDSASSSSSEESSEEVSEKIVQSEEQKVNLNQQKKFKQFSQESSFSQCCTPLHQQQQSSVNQWPQPNAIHNTPTQESISTSVEEILKKIIDMIKYIQYQQVTIPQLPQALHPQIPVSYWYPSKDYTFPNAHYTRFY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P02667-1", "uniprot_id": "CS2LA_RAT", "id": "P02667-1", "name": "Alpha-S2-casein-like A", "aln": "MKFFIFTCLVAAALAKHAVKDKPSSEES-ASVYLGKYKQGNSVFFQTPQDSASSSSSEESSEEISEKIEQSEEQKVNLNQQKKSKQFSQDSSFPQICTPYQQQ--SSVNQRPQPNAIYDVPSQESTSTSVEEILKKIIDIVKYFQYQQLTNPHFPQAVHPQIRVSSWAPSKDYTFPTARYMA--", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:***..***** :***.***** **:* ** * .*******.:**************:**** ************** *****:***.* *** :** ***** ******::.*:*** *************::**:****:* *::***:**** ** * ********.*:* ", "identical_positions": 137, "similar_positions": 26, "identity": "74.46%" }, { "cls_id": "homologset.agr.RGD:621153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R553-1", "uniprot_id": "CSTN3_RAT", "id": "Q8R553-1", "name": "Calsyntenin-3", "aln": "----MTLLLVSLLLASLLQISSGNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAG-EICGFRLH----GSG-VPFKAVILDKATGEGLIRAKEPVDCEAQKEHTFTTQAYDCVDGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGEKLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPSWQGWNKRIEYAPG-AGSLALFPGIRLETCDEPLWN-----IQATIELQTSHVAKGCDRDNYSERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGPAGLGSGPQDGLSDHFTLSFWMKHSVTPSK--------GKKEEETIVCNTIQNEDGYSHYSLTVHGCRIAFLYWP-----LLESARPVKFLWKLEQVCDDEWHHYALNLEFPT-VTLYTDGISFD---------PALIHDNGLIHPPRREPALMIGACWSEEKNKEKEKGGENSTDTTSGDPLPIHHYFHGYLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQ----ILLSGT-AHFARPAVDFEGPEGVPLFPDLQITCSISHQVEAKADESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDPERESLLLDMASLQQRGLELTN--RSAYLTIAGVETITVYEEILRQARYQLRHGAALYARKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQ-FLHRG--------------------HQPPPEMAGHSLASSHRNSMVPS---------------AATLIIVVCVGFLVLMVILGLVRIHSLHRRVSGTGGPSGASADPKDPDLFWDDSALTIIVNPMESYQNQQTGVAGVAGGQQEEEDSSDSEAADSPSSDERRIIE-----SPPHRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JH7-1", "uniprot_id": "CSTN3_MOUSE", "id": "Q99JH7-1", "name": "Calsyntenin-3", "aln": "----MTLLLVSLLLASLLQISSGNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAG-EICGFRLH----GSG-VPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGTNTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGEKLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPSWQGWNKRIEYAPG-AGSLALFPGIRLETCDEPLWN-----IQATIELQTSHVAKGCDRDNYSERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGPAGLGSGPQDGFSDHFTLSFWMKHSVTPSK--------GKKEEETIVCNTVQNEDGYSHYSLTVHGCRIAFLYWP-----LLESARPVKFLWKLEQVCDDEWHHYALNLEFPT-VTLYTDGISFD---------PALIHDNGLIHPPRREPALMIGACWTEEKNKEK-KGGENSTDTASGDPLLIHHYFHGYLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQ----ILLSGT-AHFARPAVDFEGPEGVPLFPDLQITCSISHQVEAKADESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDPERESLLLDMASLQQRGLELTN--TSAYLTIAGVETITVYEEILRQARYQLRHGAALYARKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQ-FLHRG--------------------HQPPPEMAGHSLASSHRNSMVPS---------------AATLIIVVCVGFLVLMVILGLVRIHSLHRRVSGTGGPSGASTDPKDPDLFWDDSALTIIVNPMESYQNQQTCVAGVAGGQQEEEDSSDSEAADSPSSDERRIIE-----SPPHRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQT9-1", "uniprot_id": "CSTN3_HUMAN", "id": "Q9BQT9-1", "name": "Calsyntenin-3", "aln": "----MTLLLLPLLLASLLASCSCNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAG-EICGFRLH----GSG-VPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPSWQGWNKRIEYAPG-AGSLALFPGIRLETCDEPLWN-----IQATIELQTSHVAKGCDRDNYSERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGPSGLGSGPQDSLSDHFTLSFWMKHGVTPNK--------GKKEEETIVCNTVQNEDGFSHYSLTVHGCRIAFLYWP-----LLESARPVKFLWKLEQVCDDEWHHYALNLEFPT-VTLYTDGISFD---------PALIHDNGLIHPPRREPALMIGACWTEEKNKEK-EKGDNSTDTTQGDPLSIHHYFHGYLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQ----ILLSGT-AHFARPAVDFEGTNGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDPERESLLLDTTSLQQRGLELTN--TSAYLTIAGVESITVYEEILRQARYRLRHGAALYTRKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQ-FLHRG--------------------HQPPPEMAGHSLASSHRNSMIPS---------------AATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGAGGPPGASSDPKDPDLFWDDSALTIIVNPMESYQNRQSCVTGAVGGQQEDEDSSDSEVADSPSSDERRIIE-----TPPHRY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PFP2-1", "uniprot_id": "CSTN3_DANRE", "id": "A0A8M9PFP2-1", "name": "Calsyntenin-3", "aln": "---MARMSFLSFLLFCLTSVAHGNKANKHKPWIETEYQGIVMENDNTVLLNPPLFALDKDAPLHYAG-EICGFRVHNGPGGSGSAQFEAVVLDRSTGEGLVRSKEPLDCESQKEHSFTIQAYDCGEGPDGTNSKKSHKATVHVRVNDVNEFSPVFVERRYEASVPEGRLFDRIVRVEAVDADCSPQYSQICFYDIITPNVPFTIDNDGNIKNTEPLDSKRQRVHSFWVTAFDCGKNRAQADAQVIVTVKPSCKPGWIGWTKRIEYTPG-SGSIPLFPNLHLETCEETVWN-----IQATVELQTSHIGKGCDRDSYSDRSVRRLCGAVRGEVDLLPPPSPATNWTAALPTLPSSDSSLVFSFNGSTHVAVVPDSVASAVSG------DHFTLQLWMRRGGASTQPPANQARGTRKEEETIVCSTVKNDDSYSHYSLSVHGCRLSLFYWP-----DVSAARPVKFLWKLEQVCDSEWHHLSLSVQFPS-VTLYVDGVTFD---------PALIHDNGAIPNPAPHQRLVIGACWEPE---EKPKDIVNNTMPENKDTGKFVSGYKGLLSGVTVRPGNVEPHSVVECLYACREGLDFGDLETLGSGMKVHVNPSQSVLVLEGDDIESFNRAVQQVTYRNSLRFATPGVRPLKLTTSLRCFSEESCLSLRQLEGYLVVLQPDAPQ----ISLSGVGPHLARPAAEFEGPQGVPLFPELRIVCSLSHAVNTAA----QGMEGGALMSDAVAHTLDGCEVQPLGEELNTEREELLVDMESLRERGLDIIN--TTAYIAITGAESISVYEDVLRSIHYRLAKGSARFERRFRLSCSEMNGRYTSNELTLEVNFLHSLDSLYHPSHLLASQQQFLHPS--------------------HHTG-ELSGHTLPNPHRNSVVPG---------------AATVIIMVCVGFLVVMVILGVFRIRSIHRRGEGARG------GGKEGGNQWDDSALTIIVNPMETYENRMGITTDMEGECEDEEEVVDS--PDDTSDDQRIIIKKEGRDSAPRRY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V498-1", "uniprot_id": "CSTN1_DROME", "id": "Q9V498-1", "name": "Calsyntenin-1", "aln": "MTFHKTFGYGCIVLICFELLFAGVETSSENDDEYLTQKEIILEKSYHGLIRENETLVEITPLIKVNEEKICNFHIL-----KKPYHEIPFKIELVNNLGILKARRTLNCENRKSYHFEICAIYCDGTP-------SNTANVHITVIDVNEYAPTFLEPSYVIEVDEGRLYNEILRVEASDKDCTPLFGDVCKYEILNNDEPFSIDNEGSIKNTEPLSHKASHNHILSVVAYDCAMKESAP-IMVSIKVRRVCETKFVGMPERIDYTSGSTESLQLFPNARLDLCDISCKNEEDLRIHSSIALKTKHISFGCDRDISN-------CTSGQKVKDLLP---HGAEWTKELSYDEGLEP--IFHFDGSTGVVVPATVIDHYDFS-----SQPFSILTLFRHNSQVEIN--------KHVKEHIVCSADDHKMNRHHMALFVRNCRLIFLLRKNFNEGDLNIFSPAEWRWKIPEVCDNEWHHYVLNVEDSSKVDLFIDGVRFENSIENRHSNPEVIDDWPLHAAHGVNTSLAIGACYQSLENRLK--------HGFNGDISEVKVSLNSVLTAEDIKCG----TTCAEHLLAPKP-LQSNNEKSYSDNSQIKENIEMNEIYISAKNKHDIEQFMRKVQYINTKQKPTVGRRNIEVLTTLNCKNE-SSLRLPPIETYIMVNEPIAPLGIDIDVVSASLETSDLTPPSYSPKIAISGTSNKLVSYQEIKLGVHILEKTCIDSVSKNNGKLEEKNHIDSCSVVVF-PSLNPDHEDIKIDGDESLSSSMDIKTNINKDGVEMIGKDTISNYINVLRSLVYSNKKPAYYLNRVFKLSCAQQSSQYKSGEYTLTLTVLHPKQTLFKSTNVLPSSLSKVNFIGNTDNETSFHRNSGSVNGNDNNQPTESKVYSYSLLHTNNVQEPKSHIHSFIHKAEGSHVTMLIILVSVFLAVLLCGVSIARLKNNQKYIEHHQP----CPKISDDGLIWDDSALTITINPMQADVTSDASSESENSESEDEEALKDGFTHINQLEWDNSNIFQQ---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::* .: ::...: : *::*:. *:. :: . :: :**.*:: . .. :: .. *:::::..::** :*.: * * * * *:.*.**: * ****::*.*:* * * **:*::.*:**** * **:* :.::* *:*:. : ** ***:*.*:*** *. . .: : : *.*:**. :.: * : *: *:. : * :**:*:.* : *: ***. :*: *: . * *:::: *:*.*:. ***** . * : **** ::** *. . :. :: *:*: * * . : *:: :::. :: :* ***.: .:. . * :* *:.**: :: :. *.:: **: :***.**** *.:: .: * *: **: *: * :*.* . * ****: * . * . :. *:. :: * * * * : *: : :: ... ::: * . . : :...: . ::: :::* * *: : .* * * :.: *::.* .* *.: : :* *::* :* ** :*. .. .:. .:. .: : . : . . : :*.*.: . .*:.::*.: :* . . .::: . . : : * ::*: * ::**. * : : * *:***:: ..:*.*.* : :..**. : : :.:::*.*. :: :: * :: . * *.: .: :**:*.* : *:: :.: *::. :: . .: . ******** :***:: . . . :::* *. . . :. * ", "identical_positions": 201, "similar_positions": 327, "identity": "19.25%" }, { "cls_id": "homologset.agr.RGD:621155", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESQ4-1", "uniprot_id": "NMUR2_RAT", "id": "Q9ESQ4-1", "name": "Neuromedin-U receptor 2", "aln": "-------------------------------------------------MGKLENASWIH-----DPLMKYLNSTEEYLAHLCG----------------PKRSDLSLPVSVAYALIFLVGVMGNLLVCMVIVRHQTLKTPTNYYLFSLAVSDLLVLLLGMPLEIYEMWHNYPFLFGPVGCYFKTALFETVCFASILSVTTVSVERYVAIVHPFRAKLESTRRRALRILSLVWSFSVVFSLPNTSIHGIKFQHFPNGSS-VPGSATCTVTKPMWVYNLIIQATSFLFYILPMTLISVLYYLMGLRLKRDESLEAN--------------------------KVAVNIHRPSRK-------------------------SVTKMLFVLVLVFAICWTPFHVDRLFFSFVE------EWTESLAAVFNLIHVVSGVFFYLSSAVNPIIYNLLSRRFRAAFRNVVSPTCKWCHP-------------------------------------------------------RHRPQGPPAQKIIFLTECHLVELTEDAG--------------------------------------------------------------------------------PQFPGQSSIHNTN--------------------LTTAPCAGEVP--------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZ39-1", "uniprot_id": "NMUR2_MOUSE", "id": "Q8BZ39-1", "name": "Neuromedin-U receptor 2", "aln": "-------------------------------------------------MGKLENASWIH-----DSLMKYLNSTEEYLAYLCG----------------PKRSDLSLPVSVVYALIFVVGVIGNLLVCLVIARHQTLKTPTNYYLFSLAVSDLLVLLLGMPLEVYELWHNYPFLFGPVGCYFKTALFETVCFASILSVTTVSIERYVAIVHPFRAKLESTRRRALRILSLVWSFSVVFSLPNTSIHGIKFQQFPNGSS-VPGSATCTVTKPIWVYNFIIQATSFLFYILPMTLISVLYYLMGLRLKRDESLEAD--------------------------KVTVNIHRPSRK-------------------------SVTKMLFVLVLVFAICWTPFHVDRLFFSFVD------EWTESLAAVFNLIHVVSGVFFYLSSAVNPIIYNLLSRRFRAAFRNVVSPSCKWCHP-------------------------------------------------------QHRPQGPPAQKVIFLTECHLVELTEDAG--------------------------------------------------------------------------------PQFPCQSSIHNTQ--------------------LTTVPCVEEVP--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZQ4-1", "uniprot_id": "NMUR2_HUMAN", "id": "Q9GZQ4-1", "name": "Neuromedin-U receptor 2", "aln": "----------------------------------------------MSGMEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCG----------------PRRSHFFLPVSVVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSL-VPGSATCTVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEAD--------------------------EGNANIQRPCRK-------------------------SVNKMLFVLVLVFAICWAPFHIDRLFFSFVE------EWSESLAAVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQAAFQNVISSFHKQWHS-------------------------------------------------------QHDPQLPPAQRNIFLTECHFVELTEDIG--------------------------------------------------------------------------------PQFPCQSSMHNSH--------------------LPAALSSEQMSRTNYQSFHFNKT--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFW6-1", "uniprot_id": "Q9VFW6_DROME", "id": "Q9VFW6-1", "name": "", "aln": "----------------------MAVKMLPTN-----------SSGVLAT-----DLQLFHNEKFLLNLTQVLNISADNLTSLL---QGLEPEELLPTVTPMTPLSLLATLSVGYALIFIAGVLGNLITCIVISRNNFMHTATNFYLFNLAISDMILLCSGMPQDLYNLWHPDNYPFSDSICILESVLSETAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAVKFIFAIWIAALLLALPQAIQFSVVMQGM---------GTSCTMKN--DFFAHVFAVSGFLFFGGPMTAICVLYVLIGVKLKRSRLLQ---ALPRR--------------------CYDVNRGISAQT-------------------------RVIRMLVAVAVAFFICWAPFHAQRLMAVYGS---TSGIESQWFNDVFSILDYTSGVLYFLSTCINPLLYNIMSHKFREAFKVTLARHFGLGG---KNQGRGLPHTYSALRRNQTGSLRLHTTDSVRTT----------MTSMATTTTGLNGSANGSGNGTTTGQSVRLNRVSLDSVQMQ-------GQNRSRQDLFDN------PRRMLQTQISQLSSVGDAHSLLEEDLQFPGEPLQRQPTMCSIDELTDDLAISRSRLKLTRITRPPGGVTGGVAGGSTTGAAGSGGVSGDESSGKVRKAKVKVLKSSSPFKGLRTKFNWRARRKGSHKPHEKGATVNGGDTEERAAF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFW5-1", "uniprot_id": "Q9VFW5_DROME", "id": "Q9VFW5-1", "name": "", "aln": "MLQGVAITIANDSNDDGINQSFMAHVSPSPNQSPSIGVGIGIASSTMANPSESPEMLLLKNDKFLTHVAHLLNITTENLSNLLGSTNGTNASTMAADSPVDESLTLRTALTVCYALIFVAGVLGNLITCIVISRNNFMHTATNFYLFNLAVSDLILLVSGIPQELYNLWYPDMYPFTDAMCIMGSVLSEMAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAIKFIFAIWLAAFLLALPQAMQFSVVYQNE---------GYSCTMEN--DFYAHVFAVSGFIFFGGPMTAICVLYVLIGVKLKRSRLLQ---SLPRR--------------------TFDANRGLNAQG-------------------------RVIRMLVAVAVAFFLCWAPFHAQRLMAVYGLNLINIGISRDAFNDYFRILDYTSGVLYFLSTCINPLLYNIMSHKFREAFKITLTRQFGLARNHHHQQSQHHQHNYSALLR-QNGSMRLQPASCSVNNNALEPYGSYRVVQFRCRDANHQLSLQDSIRTTTTTTTINSNSMAAGNGVGGGAGGGGGGRRLRKQELYGPGPGTAVPHRMLQAQVSQLSSLGDANSLLEAEVVDRHYASGRAKRALLATKSGALLVTPPQSGDPSEVSQPATRLKLTRVISRRDEVAN---TSTPPFCGSHSLPDPETCQSASVAGRSSRKFPWRKRRQKTEDPSSEGLTYGSPKSQ-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8ITC9-1", "uniprot_id": "PK1R_DROME", "id": "Q8ITC9-1", "name": "Pyrokinin-1 receptor", "aln": "-------------------------------------------------------------------------MSAGNMSHDLG--------------PPRDPLAIVIPVTVVYSLIFITGVVGNISTCIVIKKNRSMHTATNYYLFSLAISDFLLLLSGVPQEVSYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAIRIIVLVWIMAIVTAIPQAAQFGIEHYSG---------VEQCGIVR--VIVKHSFQLSTFIFFLAPMSIILVLYLLIGVHLYRSTLVEGPASVARRQQLKSVPSDTILYRYGGSGTAMSFNGGGSGAGTAGLMGGSGAQLSSVRGRLNHYGTRRVLRMLVAVVVCFFLCWAPFHAQRLIAIYAP--ARGAKLRDQHEFVYTVMTYVSGVLYYLSTCINPLLYNIMSHKFREAFKAVLFG---------------------------------------------------------------KKVSKGSLNSRNNIESRRLRRALTNS-----------------------------------SQTQRFS------------------------------------IESAEQPKPSIMQNP---------------------TNKPPVAAQYAMIGVQVN-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8ITC7-1", "uniprot_id": "CAPAR_DROME", "id": "Q8ITC7-1", "name": "Neuropeptides capa receptor", "aln": "-------------------------MNSSTDPTFSELNASFTNTPDTLFATSVSSDPSHGFGEEDYACGTFNCSPKEFVAFVLG--------------PQTLPLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVFLYWHQYPDLFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALWIVSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSPKIVNEIPVFEVSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLG-------------------------VQQGTNNRETRNS--------------------QMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKN-------MDNYLDINEALFSIAGFAYYVSCTVNPIVYSVMSRRYRVAFRELLCGKAVGAYYN--------------------------------------------SGFARDHSSFRESSAYDRVHSVHVRASQHPNKFETDSS-------------------------------------------------------------------------------SANRVLIKKTYSLP--------------------LPKNADSTVLSTTDIVIVLENSHTVCEEPKVENDIWIENEETCI-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: ::: : **:.**:**: .*:** :: ::*.**:***.**:**:: * *:* :: * * * : * .:::::.:.::**::** **: **:::: :* :.: ::* .: * : : : :*: ** * :** :. :: : * * :** .:.: * :** *** :**: : : : :*. :::* :**::*.::*:::: **: : . . . . . . ", "identical_positions": 63, "similar_positions": 98, "identity": "8.65%" }, { "cls_id": "homologset.agr.RGD:621156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83883-1", "uniprot_id": "RL36A_RAT", "id": "P83883-1", "name": "Large ribosomal subunit protein eL42", "aln": "MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P83882-1", "uniprot_id": "RL36A_MOUSE", "id": "P83882-1", "name": "Large ribosomal subunit protein eL42", "aln": "MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P83881-1", "uniprot_id": "RL36A_HUMAN", "id": "P83881-1", "name": "Large ribosomal subunit protein eL42", "aln": "MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q969Q0-1", "uniprot_id": "RL36L_HUMAN", "id": "Q969Q0-1", "name": "Ribosomal protein eL42-like", "aln": "MVNVPKTRRTFCK--KCGKHQPHKVTQYKKGKDSLYAQGRRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61485-1", "uniprot_id": "RL36A_DANRE", "id": "P61485-1", "name": "Large ribosomal subunit protein eL42", "aln": "MVNVPKTRRTYCK--KCKKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLT7-1", "uniprot_id": "Q9VLT7_DROME", "id": "Q9VLT7-1", "name": "", "aln": "MVNVPKQRRTFCK--KCKVHKLHKVTQYKKSKERKGAQGRRRYDRKQQGFGGQTKPIFRKKAKTTKKIVLRMECTE--CKYRKQTPLKRCKHFELGGDKKRKGQMIQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX28-1", "uniprot_id": "RL44B_YEAST", "id": "P0CX28-1", "name": "Large ribosomal subunit protein eL42B", "aln": "MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVK--CKTRAQLTLKRCKHFELGGEKKQKGQALQF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX27-1", "uniprot_id": "RL44A_YEAST", "id": "P0CX27-1", "name": "Large ribosomal subunit protein eL42A", "aln": "MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVK--CKTRAQLTLKRCKHFELGGEKKQKGQALQF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** *:*:** .* * ******* .* ***:*******.*:******:*:********:***:**.: *: : .:**********:**:*** :**", "identical_positions": 69, "similar_positions": 20, "identity": "63.89%" }, { "cls_id": "homologset.agr.RGD:621157", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LXI1-1", "uniprot_id": "A0ABK0LXI1_RAT", "id": "A0ABK0LXI1-1", "name": "Thioredoxin", "aln": "EQDSVWSLKSPKLLQAPALAPPLETKVLVPRLRARQPGARPALGQSLSCSSGLFWPRPLETAPPFGGVVWARPAGAPWRAREARELVPAARARPPRPAALRPVSIKRRRAPHSAASSVGCLGSISIGFCRNSCGSLPATAKMVKLIESKEAFQEALAAA-GDKLVVVDFSATWCGPCKMIKPFFHSLCDKYSN-VVFLEVDVDDCQDVAADCEVKCMPTFQFYKKGQKVGEFSGANKEKLEATITEFA---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10639-1", "uniprot_id": "THIO_MOUSE", "id": "P10639-1", "name": "Thioredoxin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MVKLIESKEAFQEALAAA-GDKLVVVDFSATWCGPCKMIKPFFHSLCDKYSN-VVFLEVDVDDCQDVAADCEVKCMPTFQFYKKGQKVGEFSGANKEKLEASITEYA---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10599-1", "uniprot_id": "THIO_HUMAN", "id": "P10599-1", "name": "Thioredoxin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MVKQIESKTAFQEALDAA-GDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSN-VIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IFW4-1", "uniprot_id": "THIOT_DROME", "id": "Q8IFW4-1", "name": "Thioredoxin-T", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MVYPVRNKDDLDQQLILA-EDKLVVIDFYADWCGPCKIIAPKLDELAQQYSDRVVVLKVNVDENEDITVEYNVNSMPTFVFIKGGNVLELFVGCNSDKLAKLMEKHAGVYTDEAADVKAVHIDGECIVDLTAESSESDNDNNNVNEVSAHDENAVLEH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V429-1", "uniprot_id": "THIO2_DROME", "id": "Q9V429-1", "name": "Thioredoxin-2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MVYQVKDKADLDGQLTKA-SGKLVVLDFFATWCGPCKMISPKLVELSTQFADNVVVLKVDVDECEDIAMEYNISSMPTFVFLKNGVKVEEFAGANAKRLEDVIKANI---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47938-1", "uniprot_id": "THIO1_DROME", "id": "P47938-1", "name": "Thioredoxin-1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MASVRTMNDYHKRIEAA-DDKLIVLDFYATWCGPCKEMESTVKSLARKYSSKAVVLKIDVDKFEELTERYKVRSMPTFVFLRQNRRLASFAGADEHKLTNMMAKLVKA-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VUG9-1", "uniprot_id": "Q9VUG9_DROME", "id": "Q9VUG9-1", "name": "Thioredoxin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MAAMQKKVIIVDSKSYFDKLIDDAGTNKYVLVEFFATWCGPCAMIGPRLEQLASDYFGRMLVLKIDVDENEDLAVQYEVNSMPTFLIIKNRVTLIQFVGGNVERVVSTVEKFVGKVEDSKEHKSKEGGASSATVPKLER-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22803-1", "uniprot_id": "TRX2_YEAST", "id": "P22803-1", "name": "Thioredoxin-2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MVTQLKSASEYDSALASG--DKLVVVDFFATWCGPCKMIAPMIEKFAEQYSD-AAFYKLDVDEVSDVAQKAEVSSMPTLIFYKGGKEVTRVVGANPAAIKQAIASNV---------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P22217-1", "uniprot_id": "TRX1_YEAST", "id": "P22217-1", "name": "Thioredoxin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MVTQFKTASEFDSAIAQ---DKLVVVDFYATWCGPCKMIAPMIEKFSEQYPQ-ADFYKLDVDELGDVAQKNEVSAMPTLLLFKNGKEVAKVVGANPAAIKQAIAANA---------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25372-1", "uniprot_id": "TRX3_YEAST", "id": "P25372-1", "name": "Thioredoxin-3, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------MLFYKPVMRMAVRPLKSIRFQSSYTSITKLTNLTEFRNLIKQN--DKLV-IDFYATWCGPCKMMQPHLTKLIQAYPD-VRFVKCDVDESPDIAKECEVTAMPTFVLGKDGQLIGKIIGANPTALEKGIKDL----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .* : ::* * ***** : . . .: : . : :**. ::: :: .***: : : : . * : : : ", "identical_positions": 14, "similar_positions": 31, "identity": "4.68%" }, { "cls_id": "homologset.agr.RGD:621158", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49301-1", "uniprot_id": "CLC10_RAT", "id": "P49301-1", "name": "C-type lectin domain family 10 member A", "aln": "--------------------------------------------------MTMAYENFQNLGSEEKNQ--EAGKAPPQSFLCNILSWTHLLLFSL---GLSLLLLVVISVIGSQNSQLRRDLETLRTTLDNTTSNTKAELQALASRGDSLQTGINSLK----------------------------VEVDDHGQELQAGRGLSQKVASLESTVEKKEQTLRTDL---SEITDRVQQLGKDLKTLTCQLASLK---------NNGS-AVACCPLHWMEHEGSCYWFS-QSGKPWPEADKYCQLENSNLVVVN--SLAEQNFLQTHMGSVV----TWIGLTD-QNGPWRWVDGTDYEKGFTHWA----PKQPDNWYGHGLGG-GEDCAHFTS-----------DGR----------------WNDDVCQRPYRWVCEMKLAKDS--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49300-1", "uniprot_id": "CLC10_MOUSE", "id": "P49300-1", "name": "C-type lectin domain family 10 member A", "aln": "----------------------------------------------------MIYENLQNSRIEEKTQ--EPGKAPSQSFLWRILSWTHLLLFSL---GLSLLLLVVVSVIGSQNSQLRRDLGTLRATLDNTTSKIKAEFQSLDSRADSFEKGISSLK----------------------------VDVEDHRQELQAGRDLSQKVTSLESTVEKREQALKTDL---SDLTDHVQQLRKDLKALTCQLANLK---------NNGS-EVACCPLHWTEHEGSCYWFS-ESEKSWPEADKYCRLENSHLVVVN--SLEEQNFLQNRLANVV----SWIGLTD-QNGPWRWVDGTDFEKGFKNWA----PLQPDNWFGHGLGG-GEDCAHITT-----------GGP----------------WNDDVCQRTFRWICEMKLAKES--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUN9-1", "uniprot_id": "CLC10_HUMAN", "id": "Q8IUN9-1", "name": "C-type lectin domain family 10 member A", "aln": "--------------------------------------------------MTRTYENFQYLENKVKVQGFKNGPLPLQSLLQRLCSGPCHLLLSL---GLGLLLLVIICVVGFQNSKFQRDLVTLRTDFSNFTSNTVAEIQALTSQGSSLEETIASLK----------------------------AEVEGFKQERQAGVSELQEHTTQKAHLGHCPHCPSVCVPVHSEMLLRVQQLVQDLKKLTCQVATLN---------NNASTEGTCCPVNWVEHQDSCYWFS-HSGMSWAEAEKYCQLKNAHLVVIN--SREEQNFVQKYLGSAY----TWMGLSD-PEGAWKWVDGTDYATGFQNWK----PGQPDDWQGHGLGG-GEDCAHFHP-----------DGR----------------WNDDVCQRPYHWVCEAGLGQTSQESH----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W3Q0-1", "uniprot_id": "F8W3Q0_DANRE", "id": "F8W3Q0-1", "name": "", "aln": "---------------------------------------------------------MRVVSSDSGSVTVANTEYTDETESAETSDHTEFWRGDP---SVRRLAAVPSGGRWRWCAGIAGSVAALMLLLLIIT--VSVNHVKFNRKFSATEVRIQNLT----------------------------QIILNVISRTQELEQFGHKINADVSSLEFDQRMTETSMN---NLLESAQALHDKVSELKCHIDKMR---------NNNT-QELCCPDQWSLFSSNCYFFS-TDGMSWDSARDECERKRAKLLILT--SKLEKSFVVSKTKPLF----YWLGLTDGRTGEWEWLDETPYEMVRSEWR----PGQPDNWKAHGLGG-GEDCAHFHH-----------DGR----------------YNDDHCSRHYRYICKAAASAI---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TVV3-1", "uniprot_id": "A0AB32TVV3_DANRE", "id": "A0AB32TVV3-1", "name": "", "aln": "------------------------------------------------------MRRGWSLFFNFKNQPLILVPLFLLSQNMEMHSSEEYMKMEV---ECETKQSLCKGRPCSKQTGILVLLGTVGMIIFLVLISIIVQAKKLSDIETLMTDLSSSLD----------------------------SLTSKHEENQQKLERQQNVSYIQVKKQMDTVRASVSSIMS--KLKADSVRTSFMFRHPLERFLIEH---------SSEELESGCSDSAWVPFGNSCYLFS-RDKMNWTEAKDYCEEKGAWLLKIEDDSEDEWQFVTDFANPTH----YWIGLTDQNTGQWRWADGTNYTMNKEHWG----PGQPDEWTEHSLGEEGEDCAEITY-----------ESL----------------LNDLHCSSKIKFICEMKT------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z0K3-1", "uniprot_id": "B7Z0K3_DROME", "id": "B7Z0K3-1", "name": "C-type lectin domain-containing protein", "aln": "MPPAGQQLRLTALVYLALGIALLCNGSDGETRQKYANESLADADDPSPVWSQFLEDYVLSQGSSSSGSQRKSKDLPYMGADMGINGPLSYHSSAYKRPGNNIYITRRIGEAVELEPHLRKPVESQSPIVNPQFRPMTNQMLHQQHQQMQQQQQQQQLQQRQQPGFLQQLFGIGGSGGGGGSGTQQQQHVRPVPLQQQQVQQIAQQHPQQQHLVGGQPTTFRAVSENDLYLLGAIEKLVYRVDYLESRVRRSEQLIYYLMAGNNQKEVKDPCPANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAEFEKVSENEEIMAYLLNQPTHRGRDYWLGGLN-PGLLWIWSNSAKPVNPNMNLTSIAMAQKGENSTAANLVDSSEQAAEEATGEDVLNNTVQIEGKGRCLRLSYNAGKHSYVYYGQECTSRHYYICEHEDKTLDNKIKKITRELKLFE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : : . : .* . * : : . :. . .. . : ..** :. . * * . *. : * . * * : *:* : * * : : . . : :: .* .*:.*. . . * ::*: ", "identical_positions": 19, "similar_positions": 49, "identity": "4.17%" }, { "cls_id": "homologset.agr.RGD:621159", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25085-1", "uniprot_id": "IL1RA_MOUSE", "id": "P25085-1", "name": "Interleukin-1 receptor antagonist protein", "aln": "MEICWGPYSHLISLLLILLFHSEAACRPSGKRPCKMQAFRIWDTNQKTFYLRNNQLIAGYLQGPNIKLEEKIDMVPIDLHSVFLGIHGGKLCLSCAKSGDDIKLQLEEVNITDLSKNKEEDKRFTFIRSEKGPTTSFESAACPGWFLCTTLEADRPVSLTNTPEEPLIVTKFYFQEDQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25086-1", "uniprot_id": "IL1RA_RAT", "id": "P25086-1", "name": "Interleukin-1 receptor antagonist protein", "aln": "MEICRGPYSHLISLLLILLFRSESAGHPAGKRPCKMQAFRIWDTNQKTFYLRNNQLIAGYLQGPNTKLEEKIDMVPIDFRNVFLGIHGGKLCLSCVKSGDDTKLQLEEVNITDLNKNKEEDKRFTFIRSETGPTTSFESLACPGWFLCTTLEADHPVSLTNTPKEPCTVTKFYFQEDQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18510-1", "uniprot_id": "IL1RA_HUMAN", "id": "P18510-1", "name": "Interleukin-1 receptor antagonist protein", "aln": "MEICRGLRSHLIT-LLLFLFHSETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** * ****: **::**:**: :*:*::..*********.************:******** :******:***: : :********:****.****: :**** ******.:*:::****:****:.******** *********::***:****** *.* *********:", "identical_positions": 127, "similar_positions": 35, "identity": "71.35%" }, { "cls_id": "homologset.agr.RGD:621160", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52590-1", "uniprot_id": "NU107_RAT", "id": "P52590-1", "name": "Nuclear pore complex protein Nup107", "aln": "MDRSGFGGMSSPVIRDPEVTRTARKHSAHKRVLIQANQDENFGTTTPRSQIIPRTPSSFRQPFTPPS-RSLLRHPDISYIFGTEGRSPRHIQSSGYLGNLSMVTNLDDSNWAAAFSSQRLGFYTNTEHHSMTEDINLSTVMLREDDPGEAASMSMFSDFLQSFLKHSS-TTVFDLVEEYENICASQVNILSKIVSRATRWDWQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSSLE---EENMFAIAGINASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGDFSDNIEFYAKSVYWENTLHSLKQRQLLSYIGSTRPLVTELDPDAPIRQKM-PLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLHHDP----NVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNKYERAIYAALSGNLKQLLPVCDT-WEDTVWAYFRVMVDSLVEQEIRTS--VMTLDETEELPREYMEANWTLEKVFEELQATDKKRVLEENQEHYHVVQKFLILGDIDGLMDEFSKWLSKSRSSLPGHLLRFMTHLILFFRTLGLQTKEEV-SIEVLKTYIQLLINEKHTNLIAFYTCHLPQDLAVAQYALFLEGVTECEQRHQCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPSLDTATTEEDRLKIDVIDWLVFDPAQRAEALRQGNAIMRKFLALKKHEAAKEVFVKIPQDSIAEIYNQWEEQGMESPLPAED--DNAIREHLCIRAYLEAHETFNERFKHMNSAPQKP----TLLSQATFTEKVAHEHKEKKYEMDHNIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAEED-------PERAHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH74-1", "uniprot_id": "NU107_MOUSE", "id": "Q8BH74-1", "name": "Nuclear pore complex protein Nup107", "aln": "MDRSGFGGMSSPVIRDAEVTRTARKHSAHKRVLIQANQEDNFGTATPRSQIIPRTPSSFRQPFVTPSSRSLLRHPDISYILGTEGRSPRHTQSSGYLGNLSMVTNLDDSNWAAAFSSQRLGLYTNTEHHSMTEDVNLSTVMLREDDPGEAASMSMFSDFLHSFLKHSS-TTVFDLVEEYENICGSQVNILSKIVSRATPG-LQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSSLE---EENMFAIAGINASEKMVVETLFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHSLKQRQLLSHMGSTRPLVTELDPDAPIRQKL-PLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDP----NVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNKYERAIYAALSGNLKQLLPVCDT-WEDTVWAYFRVMVDSLVEQEIRTS--VMTQDDSEELPREYMEANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDVDGLMDEFSKWLSKSGSSLPGHLLRFMTHLILFLRTLGLQTKEEV-SIEVLKTYIQLLISEKHTSLIAFYTCHLPQDLAVAQYALFLEGVTEFEQRHQCLELAKEADLDVATITKTVVENICKKDNGEFSHHDLAPSLDTGTTEEDRLKIDVIDWLVFDPAQRAEALRQGNAIMRKFLALKKHEAAKEVFVKIPQDSIAEIYNQWEEQGMESPLPAED--DNAIREHLCIRAYLEAHETFNEWFKHMNSAPQKP----TLLSQATFTEKVAYEHREKKYEMDHNIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAEDD-------PERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57740-1", "uniprot_id": "NU107_HUMAN", "id": "P57740-1", "name": "Nuclear pore complex protein Nup107", "aln": "MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTS-RSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSS-STVFDLVEEYENICGSQVNILSKIVSRATPG-LQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALE---EESVFAVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKM-PLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDP----NVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNLKQLLPVCDT-WEDTVWAYFRVMVDSLVEQEIQTS--VATLDETEELPREYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEV-SIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEIYNQCEEQGMESPLPAED--DNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKP----ALIPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKED-------HERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V466-1", "uniprot_id": "NU107_DROME", "id": "Q9V466-1", "name": "Nuclear pore complex protein Nup107", "aln": "---------------------------------------------------------MADSPFPRSSRSGLLR------------------------------TTLNSSMPPQNLSHS---LLILEKSNAEQNELSLMEDTGDDLDRGKSRMDVLFPQFFDVLQAQGNGQEAFEVIQSLTQVCRGVVEQLELEIDHGMGG-EQGARQRESMLTWLRQEINTWRLLHALFYDRILLQTDRQADDEMQDGPTLGGSEKEVIQQLYALNATLREYQLVVDWLEACYD--RGEQQNPLHAHDRMMAWENTLFQLEN-LQGAAFGKGHKIVTRLDPDAPVREKR-PLHALDEEDNLRLSRAIFELIRAGRVDDGLKLCKHFGQTWRAAILEGWRLHEDPNFEQNVSVLHEKLPIEGNPRRDIWKRCAWMLADSKNYDEYSRATAGVFSGHLGSLKTLLHSNWHDLLWAHLKVQIDIRVESEIRG----CCLKNYQPMPDDYWNGRMTMEQIFEELNVAKDASVRDFAQSQLGIIQRHLILDTCGELIQHMVRWVEKDTSQQSPHQLRFMAHIVLFLRQIGRVEQERQ-AEKIVAAYVEALIARGEPQLIAYYTASLSNPLQVQLYSRFLEQVEQKRPRELAVDAALQAGLDVEQITRVTVQNIRLAHQP---LGEFGEPQSGEISAIDQRKISALEWLIHLPEQRGELLWQANAMIRTYLASSKVECMRQTFRMVPADIVQQLVSLY---GSVDNIPPRE--ECCLKEYLCYKAYLSGVDSFVEWNRLQQNRPKKPQTSHAASSQDNFTERMASERKEQAHRSEVVRWEHKVKEQAKQTIELLYNVLMFPDKGWLVDPFIAKLPENAVQLSWDHRLLQMEKLRSICIPEIALFLNEVMFKSGDFAGCVRLADEISSENRQLYKVYTKHKLAELLAKIADASLELLNSKLDPWGYPITT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52891-1", "uniprot_id": "NUP84_YEAST", "id": "P52891-1", "name": "Nucleoporin NUP84", "aln": "---------------------------------------------------------------------------------------------------------------------------MELSPTYQTERFTKFSDTLKEFKIEQN--------------NEQNPIDPFNIIREFRSAAG------QLALDLANSG--DESNVISSKDWELEARFWHLVELLLVFRN-ADLDLD---EMELHPYNSRGLFEK----KLMQDNKQLYQIWIVMVWLK-----------------ENTYVMERPKNVPTSKWLNSITSGG---LKSCDLDFPLRENTNVLDVKDKEEDHIFFKYIYELILAGAIDEALEEAKLSDNISICMILCGIQEYLNP--VIDTQIANEFNTQQGIKKHSLWRRTVYSLSQQAGLDPYERAIYSYLSGAIPNQEVLQYSDWESDLHIHLNQILQTEIENYLLENNQVGTDELILPLPSHALTVQEVLNRVASRHPSESEHPIRVLMASVILDSLPSVIHSSVEMLLDVVKGTEASNDIIDKPYLLRIVTHLAICLDIINPGSVEEVDKSKLITTYISLLKLQGLYENIPIYATFLNESDCLEACSFILSSLEDPQVRKKQIETINFLRLPASNILRRTTQRVFDETEQEYSPSNE-ISISFDVNNIDMHLIYGVEWLIEG-KLYVDAVHSIIALSRRFLLNGRVKALEQFME---RNNIGEICKNYELEKIADNISKDENEDQFLEEITQYEHLIKGIREYEEWQKSVSLLSSES---------------------------NIPTLIEKLQGFSKDTFELIKTFLVDLTSSNFADSADYEILY--------EIRALYTPFLLMELHKKLVEAAKLLKIPKFISEALAFTSLVANENDKIYLLFQSSGKLKEYLDLVARTATLSN------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .. : . : . . *:::.. . . . :. . : * *. .: * :: : : : .: . ** * : : : :*: **: . *.. . : . :. * * *:*:: *. *.*:: : : :: ** ** ::. . .* .: . * * : : :* :.. * . :* : :*: : :::. : *.** . :** : . : : *.. : ::. :: :*. : . :* . . .:::: .. .. : . :* . *:: . .. : **:::*: : : :. *. ::: :*:. * . . *. *: * : : : :*. : : . *. :: * . * : ..:.: : : . . . * * ::**: : : . *: * :* : :. .: : : : :: . . :. : : :.* . :.. : * : . ..:. : ::. : :. * : ..*: . :.* . : : : . :: . .: ::. ::.*. ::* :: . : .: : * : ", "identical_positions": 67, "similar_positions": 243, "identity": "7.03%" }, { "cls_id": "homologset.agr.RGD:621161", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31977-1", "uniprot_id": "EZRI_RAT", "id": "P31977-1", "name": "Ezrin", "aln": "-MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYVDNKGFPTWLKLDKKVSAQEVRKENPVQFKFRAKFYPEDVADELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEMHKSGYLSSERLIPQRVMDQHKLSRDQWEDRIQVWHAEHRGMLKDSAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMLREKEELMLRLQDFEQKTKRAEKELSEQIEKALQLEEERRRAQEEAERLEADRMAALRAKEELERQAQDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVNYHVQEGLQDEGAEPMGYSAELSSEGILDDRNEEKRITEAEKNERVQRQLLTLSNELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26040-1", "uniprot_id": "EZRI_MOUSE", "id": "P26040-1", "name": "Ezrin", "aln": "-MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYVDNKGFPTWLKLDKKVSAQEVRKENPVQFKFRAKFYPEDVAEELIQDITQKLFFLQVKDGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEMHKSGYLSSERLIPQRVMDQHKLSRDQWEDRIQVWHAEHRGMLKDSAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMLREKEELMLRLQDYEQKTKRAEKELSEQIEKALQLEEERRRAQEEAERLEADRMAALRAKEELERQAQDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVNYHVQEGLQDEGAEPMGYSAELSSEGILDDRNEEKRITEAEKNERVQRQLLTLSNELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15311-1", "uniprot_id": "EZRI_HUMAN", "id": "P15311-1", "name": "Ezrin", "aln": "-MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P46150-1", "uniprot_id": "MOEH_DROME", "id": "P46150-1", "name": "Moesin/ezrin/radixin homolog 1", "aln": "MSPKALNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKVMNQDVKKENPLQFRFRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNKTTHTAGFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRVRINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQEREKLQLALAARERAEKKQQ-------EYEDRLKQMQEDMERSQRDLLEAQDMIRRLEEQLKQLQAAKDELELRQKELQAMLQRLEEAKNMEAVEKLKLEEEIMAKQMEVQRIQDEVNAKDEETKRLQDEVEDARRKQVIAAEAAAALLAASTTPQHHHVAEDENENEEELTN-GDAGGDVSRDLDTDEHIKDPIED-RRTLAERNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.:****************..********************:***:*.*.** .**:** *** *:*:****:**:***********:******* :**:****:.**:*********:***.******:.**:** *.:*:*:.:**:****:****:::*:**: * .* ***.**::.**:*************:*****:********************:**:*****************.:***:***********:*:***:******* ******************:************: ** **::*: ** .*:::: * **:: ::. ::::::* * : :***: :: * :.** : :.**. : .: :* *: :: ::: . *::*.:. *...::*: . * : * :::*...* . . :* * : * . * :*.:: .* *: * * **:***:: ** :*..:*:*:***.*.* ** **.**:***********:**:****:*:*:** :", "identical_positions": 327, "similar_positions": 146, "identity": "55.71%" }, { "cls_id": "homologset.agr.RGD:621162", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCA4-1", "uniprot_id": "D3ZCA4_RAT", "id": "D3ZCA4-1", "name": "", "aln": "MRSSKSKEVPLPNPRNSQ---SKETVQ-DVTTSWDALSQTKAALRHIENKLEVAPTSTAVIDSVMDAKKS-ASATRKISRKDGRCLDDSWVSAPTSKFSKPRKEKSRSPLRATTLESNVKKNNRVEFREPLVSYRETHGTLFSLSPSHLESKHVYCIHE--EKPENGKQMVVSREDRNSHCCDFESAQPSVISDTVVRFLNDGPAIDALHSSECLMKMGVHIRTEEEMPNRTKGSENNSKPSLNSMEHDVDPNVLLLSDSSPSSTSACNSQRVGICKRQQHDVKLEKLKERIRKQWEHSEEINGHAQTLGHIDHPVMVVNVDN---SVTTKVRKVATAPPAPAYKGFNPSETKIRTPDGKVWQEAEFQSMSRELYHDLALQFADDTS-VKEKPVE--KSKEKKVVKPVRKIQKVTQLSNPECKTGGSRLISTSSWRDGQKLVKRILGPAPTMEQRARRPASSDGRGRGRGAT-GGHIGRAESDPKLDVSHKQLPRSSERSRS-RAWSENNVVKSALSLPDNKQEENAALNKDFLPVEIRGILDDLQLDSSAQTVRQEVGEVQNQKSVASVQAPRSHSPVKRKPDKITANEDPPVISKKRHYDTDEVRQYIVRQQEERRRRQHEEKKAQKEATEQKNKRLQELYRKQKEAFTKAKPVPPSDPSTSRRLQETYSKLLLEKTLLEEPA--RQHATPETQTRPGYQPSGESDKENKVQERPPSASSSSDLSLSEPPQP-LARRDL--MEPTWMQPDRLSPRVHSSQAQPLVGTTENLLSHLLHLEHVGILHKDYESVLPAKKSHNKASGPLTFTPQPYLTSQAPHPDALLKPSTSQYKSKLDRIEALKATAASLSSRIESEAKKLAGASINYGSVWNTECDGKLAAQDNGPWTKAISSPVKEG--VEDAFSARIQKMLGTCIAHATFDDELPGVGSLSEYKKLPEMIRPLSAVSSLRVKSPSPNPGGLLAQLCRKQADSSSSDIQACSKERAKRSLCSSIDSVSEGPLLSEGSLSEEEGRRDARPLLKVAEILKEKEFCAGERNPYEPIKEFQKEAEKFLPLFGHIGGTQ--SKGPWEELAKGSPHSVINIFTKSYQLYGKGFED---RGTSASRPLNATTTPLSSVSYEDDFVSSPGSGTLTEKKSALESQIDGSNLGIQEDHSSRKFAYD--LSSLDVTSQHSSGAHSAVSTR-SSASKGKKGKKEKMDWLDSFTENAQNILNDEEKVQSDSERGSPQGRKLGTSSKLAVRGYEQTLDAESTLEELSGHSVSGSSDKGRSQKTPTSPLSPSSQKLLQFDLPGTSLERSKSSVIVPPTTAGFKPTAAFTDVN-------KTEMTSTPGPKRFSPAGLQHRMAAELSYLSAIEESVRQLSDVERVRGISLAQQESVSLAQIIKAQQQRHERDMALLKLKAEQEALDCQRQLEETRNKAAQVHAESLQQVVKSQREVTEVLQDATCKIAAQQSETARLTTDAARQICEMAELTRTHLADAITTSGVPLATLYDHQRQHFPDFMKQLRTKAETDRISQSASLSQSKEGTLDSKRQKYSPSRDSYSESSRYRSQDYQRSSSGSSRQESPSVPPSKENEKKFHG-EKMETSIDEQLQTAADDSLRSDSIP-SLPDEKDSTSIATEYSLKFDESMTEDEIEEKSFRSLLPSESHRRFNMEKKRGHHDDSDEDASPDKTT--LCSTKELSMPFSGGQDSFSKFTMEMVRQYMKEEEVRAAHQCSLLRLREKALKEKTKAELAWLEHQKKHLRDKGEDDKMPPLRKKQRGLLLRLQQEKAEIKRLQEANKAARKERQLILKQQEEIERIRQTTIKLQEKLKSAGENKLGPHGDDD--AEDKAASPGPPGSETRSPSPISISSSETSSIMQKLKNMRSRMDEKHCSPVHYFFSVFTSHHWASLSVCFPNLHPKFQLYIYNQLVRFLTKREQKLMQRRQHAEELLEWKRRLDAEEAEIQQMEKQALAAWDKELAKPKTPKKELESQRTAQRGIASEEGSLVPSYSLRNSESCIPEELGSPSDLCMPSESRAQTQPGSPDHSLLTEEMIFPQELEP-DSPSKHSPP--KSSLSLSKQESSKASHRTEGHGHLPARSR---QPSYSWSDESLSMTQSETTSDQSDIEGRIRALKGELRKRKSVVEQLKKEQRKRQKERLKAQEASLLRQLETYDEFIKKTEGELSQDLDTSPTSKFQIKTLSSISEKPKIKP-HPLHRSETAKTWKSVTESERYRGSLASIAEHVDSSLSYSERATSERSLSAYAKRGVELDSRIEHLQAS-SPVLSS-RKTQTESRDSLESTPSLSPVKELNAPDQIYDVSESKAED----STQKSEIEEIESIKLERSEGEDASCKQSGGSEVLLKLDLT----SGTLSSKERPSDSANVHQDLVTPAMEVFHEKE---EDSQSNPSRDDSSQDILSAGGVPGQECRENGDSTLSGQLSVPKESSYSEDFEVSSFKKGISAD-EISKDDSEVSSPS-LRKDAQSHRDKSWLTRSSRSRTTGSGSDEEISECLGEKSLSVHSGVHSERLLELRSPTELMRSKERSDVGHEQGGTEPLPLAAVSAMEELPDFHIGDRVLIGNVQPGTLRFKGETAFAKGFWAGVELDKPEGNNNGTYDGIVYFVCKEKHGIFAPPQKISHILENFDDYIDINEDEECYSDEQYQ----EQKDIECLKDRENNIAEYFCEKSLPSIHNTEASVDEGRSLNIETD----TPEVLEVRVHQQSSVDPPTSCKENKALVPAASESVCAS--------MLSEEL-QQQQLAEQEENFSYQVSEK------PSTPLLDLLTR-EKNQLEAQLKSS-ISEEKKSKQQLETVSLLTDSLLQVFVKDTVSQLQQVKKARNEKIQLSNQECL--DQKKVLPQDSPQNIEEQSLS-VPSCFLRAELEDEKEEISSPDMCPRPESPVFGASGQEELAKRLAELEISREFLNTL-DDQDWFDEDFGLSSSHKIQKNK-----------AEETIVPLMAEPKRVPQKPCETLSVVPHTAEEVESLVHNAAEELWKWKELGQD---LHGFSIP---AKFLGCASKGLDIGNTSRRVYKQAVFDLTKEIFEEIFAEDPNLNQPVWMKPCRINSSYFRRVKNPNNLDEIKHFITTEVLKLFSLKKEPNHKTDWQKMMKFGRKKRDRVDHILVQELHEEEAQWVNYDEDELCVKMQLADGIFEALIKDTIDVLNQISEKQGRMLLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q309-1", "uniprot_id": "CE350_MOUSE", "id": "E9Q309-1", "name": "Centrosome-associated protein 350", "aln": "MRSSKSKEVPLPNPRNSQ---SKETIQ-DVTTSWDALSQTKAALRHIENKLEVTPTSTAVIDSVMDTKKS-ASATRKISRKDGRCLDDSWASAPTSKFSKPRKEKSRSPLRATTLESNVKKNNRVEFREPLVSYRETHGTPFSLSPSHLESKHVYCIHE--EKPESGKQMVVSREDRNIQCCDFESAQPSVISDTVVRFLNDGPAIDALHSSECLMKMGVHVRTEDEMPNRTKGSENNSKPSLNNMEHDVDPKVMLLSDSSPSS-SACNSQRSDISKRQQHDIKLEKLKERIRKQWEHSEEINGQAQTLGHIDHPVMVVNVDN---SVTTKVRKVATAPPAPAYKGFNPSETKIRTPDGKVWQEAEFQSMSRELYRDLALQFTDDTS-VKEKPVE--KSKEKKVVKPVRKIQKVTQLSNPECKTGSSRLISTSSWRDGQKLVKKILGPAPKMEQKERRPTSNDRSGRERVAKFGGHIGRAESDPKLDVSHKQLPRSSARSRSSRAWSETNIVKSALSLPDNKQEESAALNKDFLPVEIRGILDDLQLDSSAQAVRQEAGEGQNQKSSAPEQVPRSHSPVKRKPDKITANEDPPVISKKRHYDTDEVRQYIVRQQEERRRRQHEEKKAQKEATEQKNKRLQELYRRQREAFSKAKTVPPSDPLVSRRLQETYSKLLLEKTLLEEPA--RQHVTQDIQARPGYQPSGESDKENKIQERPPSASSSSDLSLSEPPQP-LARRDL--MEPTWMQPDRLSPRVHSSQAQPLAGTTENLLSHLLHLEHVGILHKDYESVLPAKKSHNTASGPLTFTPQPYLTSQAPHPDALLKPSTSQYKTKLDRIEALKATAASLSSRIESEAKKLAGASINYGSVWNTECDVKLAPQENGPWTKAISPPVKED--IEDAFSARIQKMLGTCVSHAAFDDELPGVGSLSEYKKLPEMIRPQSAISSLRMKSPSPKPGGLLAQLCRRQTDSSSSDIQACSQERAKRSLCSSIDSVSEGPLLSEGSLSEEEERRDARPLLKVAEILKEKEFCAGERNSYEPIKEFQKEAEKFLPLFGHIGGTQ--SKGPWEELAKGSPHSVINIFTKSYQLYGKGFED---RGTLVSRPLNATATPLSSVSYEDDFVSSPGSGTLTERKSTLESQVDGSSLGVQEEHLSRQFACD--LASVDATSQHSSGARSAGSTRSSSASKGKKGKKDKMDWLDSLTGSAQNPLIDEEKVQSDSERGSHPSRKLGTGSKLAVGDSEQTLDAESTLEDLSGHSVSGSSDKGRSQKTPTSPLSPSSQKLLQFDLPGTSLERSKSSVIVPPTTTGFKPTAAFTDVN-------KTEMASAPGPQRFSPAGLQHRMAAELSYLSALEESVRQLSDVERVRGIALAQQESVSLAQIIKAQQQRHERDLALLKLKAEQEALECQRQLEETRNKTAQVHAESLQQVVKSQREVTEVLQEATCKIAAQQSETARLTTDAARQICEMAELTRTHLADAITTSGVPLATLYDHQRQHFPDFMRKLRTKAETDRISHSASHSQSKEGAVDSKRQKFSPSRDSYSESSRYKSHDYR--SSGSSRQDSPSVPPSKENEKPFHG-EKMESSVDEQLQTAADDSLRSDSIP-SLPDEKDSTSIATEYSLKFDESMTEDEIEEKSFRSLLPSESHRRFNMEKKRGHHDDSDEDASPDKTA--LSSTKELSMPFSGGQDSFSKFTMEMVRQYMKEEEVRAAHQSSLLRLREKALKEKTKAELAWLEHQKKHLRDKGEDDKMPPLRKKQRGLLLRLQQEKAEIKRLQEANKAARKERQLILKQQEEIERIRQTTIKLQEKLKSAGEKKLGSLADDDEAEDNKAASPGPPGLETRSPSPISISSSETSSIMQKLKSMRSRMDEK-----------------------------------------FLTKREQKLMQRRQHAEELLEWKRRLDAEEAEIQQMEKQALAAWDKELVKPRTPKKEQESQRTEQKGIASEEGSPMPSYSPRNSESCIPEDLGSPSDLCVPSEARVQAQPGSPEHSTLTEEMVFSQELES-TSPSKHSPP--KSCLSMSKQESSKASHRTEGHCHLPVKSH---QPCYSWSDESLSMTQSETTSDQSDIEGRIRALKDELRKRKSVVEQLKREQRKRQKERLKAQEASLLRQLETYDEFIKKTEGELSQDLDISPTSKFQMKTLSSVSEKPKIKP-HPLHRSETAKTWKSVTESERSRGSLASIAEHVDSSLSCSERAISERSLSAYAKRGVELDSRIEHLQAS-SPDLSS-RKAQTESRDSLESAPSLSPVKELNAPDRIYDVSEAKAED----TSQKSEIQEIESMKLESSEVEDACCKQSGGSEVLLKLDLA----SETLSSKELPSDSANVQQDLDKPATETSHEKEEALKEDQSNHSTDDRSPDIQSAGGIPEQGCRESGDSTCSGQLSVPKESSYSEDFEVSSFRKGISAD-EISKDDSEGSSPSSLRKDSQSHRDRSQLTRSSRSRATGSGSDEEISECLGEKSLSVHSGVHSERLLELRSPTELMKSKERSDVGHEQGGTEPLPLAAT---EELLDFHIGDRVLIGSVQPGTLRFKGETDFAKGFWAGVELDKPEGNNNGTYDGIVYFVCKDKHGIFAPPQKISHLLENFDD-TDINEDEESYSDEQYQPYNQEQKDIKCLKDRENNIAEYFCEKSLPSMHNTDASVDKDRSLNIETD----TSEVLEVHGHQQPSVDPLISYKENKVLVSDATESVPAAAGAATSDNTFSGES-KQQQLAEKEENFYSQVLEK------PSTPLLDLLTR-EKNQLEAQLKSS-ISEEKKSKQQLETVSLLTDSLLQVFVKDTVSQLQQVKKARNEKIQLSNQEFL--DQKKVPPQDLPQNTEEQSPS-VPSCFLRSELEDEKEEISSPDMCPRPESPVFGASGQEELAKRLAELEISREFLSAL-DDQDWFDEDFGLSSSHKIQKNK-----------AEETIVPLMAEPKRAPQKPCETLLAVPHTAEEVESLVHNAAEELWKWKELGQD---LHGLSLP---TTFLGGASKGLDIGSTSRRVYKQAVFDLTKEIFEEIFAEDPNVNQPVWMKPCRINSSYFRRVKNPNNLDEIKHFITTEVLKLLSLKKEPNHKTDWQKMMKFGRKKRDRVDHILVQELHEEEAQWVNYDEDELCVKMQLADGIFETLIKDTIDVLNQISEKQGRMLLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VT06-1", "uniprot_id": "CE350_HUMAN", "id": "Q5VT06-1", "name": "Centrosome-associated protein 350", "aln": "MRSSKSKEVPLPNPRNSQ---SKDTVQADITTSWDALSQTKAALRHIENKLEVAPTSTAVCDSVMDTKKSSTSATRKISRKDGRYLDDSWVNAPISKSTKSRKEKSRSPLRATTLESNVKKNNRVEFREPLVSYREIHGAPSNFSSSHLESKHVYCVDVNEEKTESGNWMIGSREERNIRSCDFESSQSSVINDTVVRFLNDRPAIDALQNSECLIRMGASMRTEEEMPNRTKGSENNLKLSVNNMAHDTDPKALRLTDSSPSSTSTSNSQRLDILKRRQHDVKLEKLKERIRKQWEHSEETNGRGQKLGHIDHPVMVVNVDN---SVTAKVRKVATAPPAPAYKGFNPSETKIRTPDGKVWQEAEFQNMSRELYRDLALHFADDIS-IKEKPAE--KSKEKKVVKPVRKVQKVAQLSSTECRTGSSHLISTSSWRDGQKLVKKILGPAPRMEPKEQRTASSDRGGRERTAKSGGHIGRAESDPRLDVLHRHLQRNSERSRS-KSRSENNIKKLASSLPDNKQEENTALNKDFLPIEIRGILDDLQLDSTAHTAKQDTVELQNQKSSAPVHAPRSHSPVKRKPDKITANEDPPVISKRRHYDTDEVRQYIVRQQEERKRKQNEEKKAQKEATEQKNKRLQELYRKQKEAFTKVKNVPPSEPSATRRLQETYSKLLLEKTLLEEPS--HQHVTQETQAKPGYQPSGESDKENKVQERPPSASSSSDMSLSEPPQP-LARKDL--MESTWMQPERLSPQVHHSQPQPFAGTAGSLLSHLLSLEHVGILHKDFESILPTRKNHNMASRPLTFTPQPYVTSPAAYTDALLKPSASQYKSKLDRIEALKATAASLSSRIESEAKKLAGASINYGSAWNTEYDVQQAPQEDGPWTKAVTPPVKDD--NEDVFSARIQKMLGSCVSHATFDDDLPGVGNLSEFKKLPEMIRPQSAISSFRVRSPGPKPEGLLAQLCKRQTDSSSSDMQACSQDKAKISLGSSIDSVSEGPLLSEGSLSEEEGDQDGQPLLKVAEILKEKEFCPGERNSYEPIKEFQKEAEKFLPLFGHIGGTQ--SKGPWEELAKGSPHSVINIFTKSYQLYGKGFEDKLDRGTSTSRPLNATATPLSGVSYEDDFVSSPGTGTSTEKKSTLEPHS---TLSPQEDHSNRKSAYD--PSSVDVTSQHSSGAQSAASSRSSTSSKGKKGKKEKTEWLDSFTGNVQNSLLDEEKAE----RGSHQGKKSGTSSKLSVKDFEQTLDTDSTLEDLSGHSVSVSSDKGRSQKTPTSPLSPSSQKSLQFDVAGTSSERSKS-SVMPPTITGFKPNAPLTDLNPAASRTTTENMAPIPGSKRFSPAGLHHRMAAELSYLNAIEESVRQLSDVERVRGISLAQQESVSLAQIIKAQQQRHERDLALLKLKAEQEALESQRQLEETRNKAAQVHAESLQQVVQSQREVTEVLQEATCKIAAQQSETARLTTDAARQICEMAELTRTHISDAVVASGAPLAILYDHQRQHLPDFVKQLRTRTETDRKSPSVSLSQSKEGTLDSKHQKYSASYDSYSESSGYKNHDRR-SSSGSSRQESPSVPSCKENEKKLNG-EKIESSIDEQVQTAADDSLRSDSVP-SLPDEKDSTSIATEYSLKFDESMTEDEIEEQSFRSLLPSESHRRFNMEKRRGHHDDSDEEASPEKTT--LSTAKELNMPFSGGQDSFSKFTMEMVRQYMKEEEMRAAHQSSLLRLREKALKEKTKAELAWLEHQKKHLRDKGEDDKMPPLRKKQRGLLLRLQQEKAEIKRLQEANKAARKERQLILKQQEEIEKIRQTTIKLQEKLKSAGESKLDSHSDDD-TKDNKATSPGPTDLETRSPSPISISSSETSSIMQKLKKMRSRMDEK-----------------------------------------FLTKREQKLMQRRQHAEELLEWKRRLDAEEAEIRQMEKQALAAWDKELIKPKTPKKELEDQRTEQKEIASEEESPVPLYSHLNSESSIPEELGSPAVEYVPSESIGQEQPGSPDHSILTEEMICSQELESSTSPSKHSLP--KSCTSVSKQESSKGSHRTGGQCHLPIKSH---QHCYSWSDESLSMTQSETTSDQSDIEGRIRALKDELRKRKSVVNQLKKEQKKRQKERLKAQEASLIKQLESYDEFIKKTEAELSQDLETSPTAKPQIKTLSSASEKPKIKPLTPLHRSETAKNWKSLTESERSRGSLESIAEHVDASLSGSERSVSERSLSAYAKRVNEWDSRTEDFQTP-SPVLRSSRKIREESGDSLENVPALHLLKELNATSRILDMSDGKVGE----SSKKSEIKEIEYTKLKKSKIEDAFSKE-GKSDVLLKLVLEQGDSSEILSKKDLPLDSENVQKDLVGLAIENLHKSEEMLKERQSDQDMN-HSPNIQSGKDIHEQKNTKEKDLSWSEHLFAPKEIPYSEDFEVSSFKKEISA--ELYKDDFEVSSLLSLRKDSQSCRDKPQPMRSSTSGATSFGSNEEISECLSEKSLSIHSNVHSDRLLELKSPTELMKSKERSDVEHEQQVTESPSLASVPTADELFDFHIGDRVLIGNVQPGILRFKGETSFAKGFWAGVELDKPEGNNNGTYDGIAYFECKEKHGIFAPPQKISHIPENFDDYVDINEDEDCYSDERYQCYNQEQNDTEGPKDREKDVSEYFYEKSLPSVNDIEASVNRSRSLKIETDNVQDISGVLEAHVHQQSSVDSQISSKENKDLISDATEKVSIAAEDDTLDNTFSEELEKQQQFTEEEDNLYAEASEK------LCTPLLDLLTR-EKNQLEAQLKSS-LNEEKKSKQQLEKISLLTDSLLKVFVKDTVNQLQQIKKTRDEKIQLSNQELLGDDQKKVTPQDLSQNVEEQSPS-ISGCFLSSELEDEKEEISSPDMCPRPESPVFGASGQEELAKRLAELELSREFLSALGDDQDWFDEDFGLSSSHKIQKNK-----------AEETIVPLMAEPKRVTQQPCETLLAVPHTAEEVEILVHNAAEELWKWKELGHD---LHSISIP---TKLLGCASKGLDIESTSKRVYKQAVFDLTKEIFEEIFAEDPNLNQPVWMKPCRINSSYFRRVKNPNNLDEIKSFIASEVLKLFSLKKEPNHKTDWQKMMKFGRKKRDRVDHILVQELHEEEAQWVNYDEDELCVKMQLADGIFETLIKDTIDVLNQISEKQGRMLLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TW94-1", "uniprot_id": "A0AB32TW94_DANRE", "id": "A0AB32TW94-1", "name": "", "aln": "MWSRLRSEAGPPASVPSQPPFAGQDNRREISQAWNCINQTKAALRHIENRLEASPGSGVLLDSVLDTKKSSVSGGRKISRRDGRHVEESGSKS-RTRSRRSPDKSSRSPLRNSTLDSNARKPSAVEFREPLASYREASPLPVSLTQSEPEALLLPTEVDILQPDFTLSQLVYQRDTRDMQTADLDSLHSSAVDSTSVHYLNDLSALNAIQQPDQPILE-------SEGRPRTQLQAN--------------------TSQTSSPGSIASAQRLESLRQRVPDEKIEKLKEKIRRQKKHLEETEERSKLLGYLEQPVGIGTTGYNTAVPTAKVRKVAPAPPAPIYKGFNTSETKIRTSDGKVWAEEEFQNLSREIYRDLTRKLTAQSTKPKQRPREREKVKEKKPSKPVRKVHRSSSAPDSNAKP----AISTSSWRDGQKLVNMMLGPPPRLHR-EPRAQSSETQMR------TGPVPRSSSDPRLEHNRRPRHSSSERSRN--NVPPDETAGPSMSAGSDRRK---SPVTDLLSADIRGILDDLQLE--EDDSRREAVP--TSRVRASTRTSRSASPAKTT-KRAEPPEQP--VPKKRHYDAEAVRLYIVQKQEERKKRQAEARRAQREEEENKNKRLQELYRKQRAGANKGPVAP--EVPIKKRLQETYTKLLLEHTQLREEINGEAVANGSQQPRPVYQPSGESDKENKRHDRPQSATSSSDLSLPEQSQPPFSRNDLGFGGSPWLQSDQHSPALHVSSALPPS--SGHIFSQLLELDQE-----------------------------PSLPSRESRTAPQSLPSATSHK--MSRIEALKATAASLSSRIENEARKLAGVGINYGCARDTGTGLLIPNEDR--WAKPISPPVRENRTDSDELVERIQRLL--AAGQSTYDEALPGVGNLHSLREKTEMGVKQTPVAS-----------AFTSRNARKTPSPPKPVVEEVELD-------SSGGSISEGPLLSEGCISDDDMQELPRSRLTTAGFNG--GYMNGE--SLNPISRFQIEAEK-QPPFSSLSLVQGGSNGPWEELAKGSPHSVINIFTKN-MGYGKAFEERGGKSSPAVRSVLSGASSLDGIVYEDDFISSRASSQSASKRSPNGLSNGLGHFSPPDDVLSGRSAYSNRAQRSPALTPLSSPHSASSSSKRASERSLQEGQRNTFSAISDLPAEGFKKSGSEKASSRSSHRSVDTDSTLGGISIHSIHSLFGSEGKKSPRSALATPAAASPASSGSSRLSPGDCIP--SKGSVQGSGSPHAALPSSSSSSSSAVRAKSNPSPHTQSPG--------RTEHRTTAELKFAPGVLHQRLSAELNYLDAVEESVRQLGDVERVRGVSLAQQETVSLAQILKSQQQRHERDLYLLRMKAEQEALETQMQLEESRQKAARVHAELQESLLQSQQQALGGLHEATNKMINQQAEAARHTAETARHIKEMTELARSQIVGALSVPGPSITALHDQQRQHS-RSSKPHQTQTHTDSSWKSEMSPERHQSPSEVETP-----PDSLSESIPSRRPTIS---GGGSSSTQLSPPHSGQTERRTPGKDRSSSSVEDQAHTAADDSLCSNSVLGPLEEKADCASIATEYSVKFDDSMTEDDIEERSFRSLLPSEAHRRESLDKKPEAHLESDEDHNHDQSSPRASTKQDGSMPFSSGQDSFSKFTMDLVRQYMKEEEVRAQHQSSLLRLREKALREKTKAEVAWLEHQKRRLRDKGEDDKMPPLRKKQRGLIMKLQQEQAEIKRLQEANKAARRERQLLLKQQEEIERMRHTTLKLKERLKTAGDTKMESP-VSGVAESSAPPSVIVTDADTRSPSPMSVSGSETSSIMQKLKKMRSHMDEKHCSPVHYFFSVFTAHHWASLSVCLPNLHPKFQLFIYSQLVRFLTKREQQLMQRRRHAEELLEWRQRLDVEEAEVRRMEKQALAAWEKQQ-QPRSRTQTQQHSRENEHSHTSGGQSPIGQEAGSEDDDSVALSVSSVHTDLSVPEQLGSPSSDRPVSELNSAVVDALYSAEFIATDSKQSPPGKASLSSLRHSDSSRPGTVTGTSSCSKMQVHSGSKTSEPHTSDTHSATPSETTSDQSDIESRIHALKDELRKRKSVVYQLKKEQKKRQKERLKAQEASLLKQLESYNDFIQKTKAELSKGPDGTPATKPQIKTPTSASEKPRIKP-PPLQRPETSKNWKIVTESEKS--------EIVPSETSGDKDDVAPSGLQKYSSEHDDISSDEDPPTVTPTPIMGS-----PEHMDVLRSFHSSDRLSHRSNDASLVKEHSAKPEDTDFLSGEESVVSSLKSGVMEELEYANSEGSENDPSDQHSHPLLN-----LDLGLQMPSLKDVNAKSDKERLSEKDTADKPAFQDSADVGESMRLTESNLSPVEVSKHIDYPSARKTISVIDHSYTSDFSLAKREDSTRMKKTQSPTGDGYNDDFESSFESSLNHESKPTSPTAPQPKEKSFKSPIYSSEEEIEEELSVQSGSTNGNFQTESRPDLNSLGRGSKD--------VIGPSPQPQVPILPIKDELPSFCIGDRVLVSNVQPGTLRFKGQTNFANGFWAGVELDNPEGSNNGTYDGVAYFECREKHGIFAPPDKISRLPEKFEASADTEDDDSSCDDQPNR----ENKASEEQLEKRNLLNKIKEEKSDLDLYPEAREPLREQGKPLELN----IKQLSTGQSTFIKSQHNLDFNDIDCNIINECDKGPHTVPNGGDRDIILKLEDASVDNAVPLLNNLDKGTSKKQKQEDEPPAVILDLLLEGEKSRVDGLQKSTDISIEEASLDNKRALTTLADKLVENFLSDAVKQFQKIKKDKEEKLSAANQLKR--DFINEDDGLRSNNFKSRTASKTKTDTFRTFFDDDQEELSSPEHCNRPESPVLGTSGQEELVKRLAELELSRELFDVLGDEQDWFDEDFGLSSRKEQQKQKRQQQQDGISSSGEQVKTPPRPELPVQLKQPEEPAMIVPHTVQEVEKLAIAAIQEIWESCKLGHGRPSLIGVPKPQPSNCFLEGDAKASDLEAQCQRSYKLTVFDLSWEVIQDIYAEDPKLDQPQWMKPRRLNSTYFHRVKCPNNKTTVQEFVTTEVLKLCGLKKEQNQKTDWQKMIKFGRKKRDRVDHILVQELHEEESQWVNYDEDELFVKMQLADGIFDALLKDTADVLTQIQEKKFKTTL-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .*. * . ** : : : ::: :*:.:.***********:**.:* * .: ***:*:*** .*. *****:*** :::* .: :: :. .:.****** :**:**.:* . *******.**** .:: *. *: : : . . :: .*: *: : .*::* :.*.:..* *::*** .*::*::..: : .* **: . * :..:.*. * ..:** ::: * *:*****:**:* :* ** : :.: **::::** : ... *:******.***** *****.*******.***** * ***.:***:*:**: ::: : : *::* * * **** *****::: :. ...:.:. *************: :***.* :. *. *.: * * : *:.***:*: :: .* ***. . : : * .:::: : .*:*. :**********: . :::. ..: *. :..** **.* . .: . *:* :.*:****:: ** ***::****:::* * ::**:* *:**********:*: . .* .* : .:******:*****:* *.* . .. . *.:* ************ ::** **:****:**.* .** ::*.** ..*:*.:: ** :* *.. * : ::*:** *:: * :.* . . . **::.:* :.*****************.**:****..****.. :* . . :: *:*.::.**::. .* : ***::* . .::::*: *****.* . :: .** :.::* .: :: .:: ...... :: . : ** .*:*********.:*::: . :. *..* : : ** . :**..** **** * *. :. .* *:********************. ***.**: :.: . *.: : ::.*..: *****:** .:. :.::*. :. :: . : * . . : ** :: *:: :: . ::*:::. . :..:. . : .*: . *. . . * * :: . : . .*. . *: :.: .:..* *: :* . :. *: :* . . : *.* ... : :*.. . . .. :*:*. *::*::***.**.*:*******.*******::*****:******:*:********: **::*******: * ****:*:*:*:**** :.:::**::. *::** *: **:*:** *:::**:* **:**:*::: .*: ..* .:: *:*:**** : :*::.** * .: ::.. : : ** *** : .*.* . . * * . :.*: * :: .:*:::* :******* *:*: .* :: *.:*******:***:*****:***:*********:*** .::*: * :***: . :::: .: :: .****.**********::*********:** **.**********:******:*******::********************:::****:**************:****:********::*:**:**:*:**:**:.*: . .. .. ..* .. :******:*:*.***********.***:**** *******:*****:********::***.****:::*********:*: :*:: .: : .* :: :* * : : :.:..:. .:.* .* . ... * . : : . * : **:* * * *: :.:**: . * : : : . . :.:: * * ***********.**:***.********* ***:**:**************::***:*::**:**:.***:. : :*::* *:** :* ****:*** **:*.**:*.** :****: * * :. * .: : .*. *:.. : .* : .. :* : * * * *.. : :.. . : . ..* : : ::* :..:: :: : :: .: . *: : * *. : . .. *.:.* : : .. .. : . . . :: . . . . ..: . :: : : ::* *. : :** * * *.::::. . :.. :. .*:***.* *. :* * :...::: :*.* . :. : :. :** .* ******:..**** *****:* **:*********:***.*******:.** *::********:***:: *:*: * ::*:.. .*: : *:: : ::.: : : *** .: . . :. :* : : : * . . : :: . : :. * . :: . :*: . :* : :**** . **.:::. **: :. *: * :: . :: *:*.*:: *:.*:*.*:*::** ::**:. :** * : .:* :.:: * : : ::*::**:***: * ******:*:******.*******:***::..* *:************ :: **:* .*:. .* .* ::* *. ****.:*** *. * :*:*: :**:. * ... * :* :*. *: .:* ** :****: *::::*:****:::** **** *:**:**:*** *** :: *:::***** .**** *:*******:**********************:********** **********::*:*** ***.**.**: : * ", "identical_positions": 1158, "similar_positions": 961, "identity": "35.82%" }, { "cls_id": "homologset.agr.RGD:621163", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30904-1", "uniprot_id": "MIF_RAT", "id": "P30904-1", "name": "Macrophage migration inhibitory factor", "aln": "MPMFIVNTNVPRASVPEGFLSELTQQLAQATGKPAQYIAVHVVPDQLMTFSGTSDPCALCSLHSIGKIGGAQNRNYSKLLCGLLSDRLHISPDRVYINYYDMNAANVGWNGSTFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P34884-1", "uniprot_id": "MIF_MOUSE", "id": "P34884-1", "name": "Macrophage migration inhibitory factor", "aln": "MPMFIVNTNVPRASVPEGFLSELTQQLAQATGKPAQYIAVHVVPDQLMTFSGTNDPCALCSLHSIGKIGGAQNRNYSKLLCGLLSDRLHISPDRVYINYYDMNAANVGWNGSTFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14174-1", "uniprot_id": "MIF_HUMAN", "id": "P14174-1", "name": "Macrophage migration inhibitory factor", "aln": "MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************:*****************.*************:*.*:.:*******************.*********::**:*********************.****", "identical_positions": 103, "similar_positions": 12, "identity": "89.57%" }, { "cls_id": "homologset.agr.RGD:621164", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q792I0-1", "uniprot_id": "LIN7C_RAT", "id": "Q792I0-1", "name": "Protein lin-7 homolog C", "aln": "MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEG---------------------------------------------------LGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88952-1", "uniprot_id": "LIN7C_MOUSE", "id": "O88952-1", "name": "Protein lin-7 homolog C", "aln": "MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEG---------------------------------------------------LGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUP9-1", "uniprot_id": "LIN7C_HUMAN", "id": "Q9NUP9-1", "name": "Protein lin-7 homolog C", "aln": "MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEG---------------------------------------------------LGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IMT8-1", "uniprot_id": "Q8IMT8_DROME", "id": "Q8IMT8-1", "name": "Protein lin-7 homolog", "aln": "MADNAEPLTLSRDVKRSIELLEKLQASGDFPTTKLAALQKVLNSDFMTSVREVYEHVYETVDIQGSHDVRASATAKATVAAFAASEGHAHPRVVELPKTEEGKTRPYELRIEGIPLYHKTNTLIVKVYRPRIYVSIIHLIWKALSIFNFCFSGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLKQAVGSVKLVVRYTPKVLEEMEMRFDKQRNTRRRQ--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .**: *.**: *:******** **:.*. ** ***:**:*:* .:**************..* :***.****************:************* ****:*******************:************************:********* * *.**************** **:* *.::*** ", "identical_positions": 156, "similar_positions": 26, "identity": "62.9%" }, { "cls_id": "homologset.agr.RGD:621166", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TAP4-1", "uniprot_id": "LMO3_HUMAN", "id": "Q8TAP4-1", "name": "LIM domain only protein 3", "aln": "---------------MLSVQPDTKPKG----------------------------------------------------------------CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BZL8-1", "uniprot_id": "LMO3_MOUSE", "id": "Q8BZL8-1", "name": "LIM domain only protein 3", "aln": "---------------MLSVQPDTKPKG----------------------------------------------------------------CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q503U0-1", "uniprot_id": "LMO3_DANRE", "id": "Q503U0-1", "name": "LIM domain only protein 3", "aln": "---------------MLSVQPDTKPKG----------------------------------------------------------------CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKENVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25800-1", "uniprot_id": "RBTN1_HUMAN", "id": "P25800-1", "name": "Rhombotin-1", "aln": "MMVLDKEDGVP----MLSVQPKGKQKG----------------------------------------------------------------CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q924W9-1", "uniprot_id": "RBTN1_MOUSE", "id": "Q924W9-1", "name": "Rhombotin-1", "aln": "MMVLDKEDGVP----MLSVQPKGKQKG----------------------------------------------------------------CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQVDYEEGHLNGTFESQVQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8JFQ2-1", "uniprot_id": "RBTN1_DANRE", "id": "Q8JFQ2-1", "name": "Rhombotin-1", "aln": "-MVLDKEEGVP----MLSVQPKGKQKG----------------------------------------------------------------CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGSFETQVQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99MB5-1", "uniprot_id": "LMO3_RAT", "id": "Q99MB5-1", "name": "LIM domain only protein 3", "aln": "---------------MLSVQPKGKQKG----------------------------------------------------------------CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M9PI02-1", "uniprot_id": "M9PI02_DROME", "id": "M9PI02-1", "name": "", "aln": "MMTMDITKTEPGLVGLSSNQQQQQQQQSQQSNAGMNSGGQNNGPNPNGNGNVVNVVNSGGAGGGNNGNGNVQSIAAAANNNNNNNNNGSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERLVFASMANHPMLKRHVSSLGQGSPTGAAGAQNTAGGLLGGGPGGGNVNGVGMVNGPRTPGDHNNNNNGPQTPTGGGSPFAAAAAAAAAAAHMKNQLGASSXNKALGMGAAGAVVPGSGVGAGVGVGVGAASQQFYSGFGLQHQHQHQQHHQQQQQQQQLMGLGLGMGGGGGVGGGGAGSAGGPGGGAGGGGGVGSIGSGCKRYQRKFYNRN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * . : : ****.::*:*****:*** ********.****************.**:**:******** ** ******:**********: *****:***** **:******:*:* :* ***: **** : : ", "identical_positions": 97, "similar_positions": 23, "identity": "22.88%" }, { "cls_id": "homologset.agr.RGD:621167", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15178-1", "uniprot_id": "SYDC_RAT", "id": "P15178-1", "name": "Aspartate--tRNA ligase, cytoplasmic", "aln": "------------------------------MPSANASRKGQEK----------------PREIVDAAEDYAKERYGVSSMIQSQE--KPDRVLVRVKDLTVQK-ADEVVWVRARVHTSRAKGK-QCFLVLRQQQFNVQALVAVG--DHASKQMVKFAANINKESIIDVEGIVRKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAIRPEVEGEEDGRATVNQDTRLDNRIIDLRTSTSQAIFHLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKSNAYLAQSPQLYKQMCICADFEKVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVVEEIADTLVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEP--TLRLEYCEALAMLREAGVEMDDEEDLSTPNEKLLGRLVKEKYDTDFYVLDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDPQLLTERALHHGIDLEK--IKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922B2-1", "uniprot_id": "SYDC_MOUSE", "id": "Q922B2-1", "name": "Aspartate--tRNA ligase, cytoplasmic", "aln": "------------------------------MPSTNASRKGQEK----------------PREIVDAAEDYAKERYGISSMIQSQE--KPDRVLVRVKDLTVQK-ADDVVWVRARVHTSRAKGK-QCFLVLRQQQFNVQALVAVG--DHASKQMVKFAANINKESIIDVEGVVRKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAIRPEVEGEEDGRATVNQDTRLDNRVIDLRTSTSQAIFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLYKQMCICADFEKVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVVEEIADTLVQIFKGLQERFQTEIQTVSKQFPCEPFKFLEP--TLRLEYCEALAMLREAGVEMDDEEDLSTPNEKLLGRLVKEKYDTDFYVLDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDPQLLTERALHHGIDLEK--IKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14868-1", "uniprot_id": "SYDC_HUMAN", "id": "P14868-1", "name": "Aspartate--tRNA ligase, cytoplasmic", "aln": "------------------------------MPSASASRKSQEK----------------PREIMDAAEDYAKERYGISSMIQSQE--KPDRVLVRVRDLTIQK-ADEVVWVRARVHTSRAKGK-QCFLVLRQQQFNVQALVAVG--DHASKQMVKFAANINKESIVDVEGVVRKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAVRPEAEGEEEGRATVNQDTRLDNRVIDLRTSTSQAVFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLYKQMCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVMEEIADTMVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEP--TLRLEYCEALAMLREAGVEMGDEDDLSTPNEKLLGHLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDPQLLTERALHHGIDLEK--IKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04802-1", "uniprot_id": "SYDC_YEAST", "id": "P04802-1", "name": "Aspartate--tRNA ligase, cytoplasmic", "aln": "MSQDENIVKAVEESAEPAQVILGEDGKPLSKKALKKLQKEQEKQRKKEERALQLEAEREAREKKAAAEDTAKDNYGKLPLIQSRDSDRTGQKRVKFVDLDEAKDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEAEAAGLPVVNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSVFEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMAFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGIEMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKYSNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGGIGLERVVMFYLDLKNIRRASLFPRDPKRLRP", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :* *** .** **** **:.** .:***:: :..: *:. ** * :*. * .*****.:* :* .**.**** :*.** .. . **:***:*..:* ***: *.*:*:**:: * *.* *::*:*: ***.** : **: *:** *.*.*.* * ..** ***** *:***** *.**:*::*:*:*.**** * .* *.*::***::.*.****:.** *:***.:********: ** * ****:*: ********:******:***.***:****: *****:: ::: :* **. * :** **: * **:* * **: : :** * *.: *** ** *:.* :**** ***:**:**::*******:***:** :********* *** *****:**************** ** ** **:. *. :* * *.* :*.*************.*::*.*:*:*::*:******** *", "identical_positions": 284, "similar_positions": 125, "identity": "50.99%" }, { "cls_id": "homologset.agr.RGD:621168", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70249-1", "uniprot_id": "OGG1_RAT", "id": "O70249-1", "name": "N-glycosylase/DNA lyase", "aln": "-MLFSSSLSSSMRHRTLTSSPALWASIPCPRSELRLDLVLASGQSFRWREQSPAHWSGVLADQVWTLTQTEDQLYCTVYRGDKGQ-------------------------------------VGRPTLEELETLHKYFQLDVSLTQLYS-HWASVDSHFQSVAQKFQGVRLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLVQLDDVTYHGFPNL---HALAGPEVETHLRKLGLGYRARYVCASAKAILEEQGGPAWLQQ-------LRVASYEEAHKALCTLPGVGTKVADCICLMALDKPQAVPVDIHVWQIAHRDYGWQPKTSQTKGPSPLAN-------------KELGNFFRNLWGPYAGWAQAVLFSADLRQ------------------QNLSREPPAKRKKGSKKTEG------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08760-1", "uniprot_id": "OGG1_MOUSE", "id": "O08760-1", "name": "N-glycosylase/DNA lyase", "aln": "-MLFRSWLPSSMRHRTLSSSPALWASIPCPRSELRLDLVLASGQSFRWKEQSPAHWSGVLADQVWTLTQTEDQLYCTVYRGDDSQ-------------------------------------VSRPTLEELETLHKYFQLDVSLAQLYS-HWASVDSHFQRVAQKFQGVRLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPNL---HALAGPEAETHLRKLGLGYRARYVRASAKAILEEQGGPAWLQQ-------LRVAPYEEAHKALCTLPGVGAKVADCICLMALDKPQAVPVDVHVWQIAHRDYGWHPKTSQAKGPSPLAN-------------KELGNFFRNLWGPYAGWAQAVLFSADLRQ------------------PSLSREPPAKRKKGSKRPEG------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15527-1", "uniprot_id": "OGG1_HUMAN", "id": "O15527-1", "name": "N-glycosylase/DNA lyase", "aln": "-MPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQ-------------------------------------ASRPTPDELEAVRKYFQLDVTLAQLYH-HWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSL---QALAGPEVEAHLRKLGLGYRARYVSASARAILEEQGGLAWLQQ-------LRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTN-------------KELGNFFRSLWGPYAGWAQAVLFSADLRQ------------------SRHAQEPPAKRRKGSKGPEG------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7V0N6-1", "uniprot_id": "A0A8N7V0N6_DANRE", "id": "A0A8N7V0N6-1", "name": "N-glycosylase/DNA lyase", "aln": "----------MSQHALLSASCKAWRSLSCPRSELRLDLTLGCGQTFRWRETADSHWTGVMRGKVWTLTQTEDTLWYYVYSHNNNPGPENRQKGKVEEEEQLLGKMSKRTTCIKQEDEGLCTVLSEPDKKEEELLRDYFQLDVKLGDLYK-NWSTVDPHFKHTANIFTGVRLLRQDPVECLFSFICSSNNHISRIQGMVERLCQTLGTLLCKLDDVAYHDFPSL---QDLTDPCVEMRLRDLGFGYRARFLQQSSQMIMNSHH-PDWLQS-------LRSTPYLQARDALRTLPGVGLKVADCVCLMSLDKFEALPVDTHVWQIAKRDYNFAPGTSQKT-LTDRVY-------------KEIGDFYRKLWGPYAGWAQSVLFCADLKKFQKLKEEVLSEDKTELKIDERKRDRCAEKQKTQKKKSKRT----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53397-1", "uniprot_id": "OGG1_YEAST", "id": "P53397-1", "name": "N-glycosylase/DNA lyase", "aln": "-------------------MSYKFGKLAINKSELCLANVLQAGQSFRW------IWDEKLNQYSTTMKIGQQEKYSVVILRQDEENEILEFVAVG---------------------------DCGNQDALKTHLMKYFRLDVSLKHLFDNVWIPSDKAFAKLSP--QGIRILAQEPWETLISFICSSNNNISRITRMCNSLCSNFGNLITTIDGVAYHSFPTS---EELTSRATEAKLRELGFGYRAKYIIETARKLVNDKAEANITSDTTYLQSICKDAQYEDVREHLMSYNGVGPKVADCVCLMGLHMDGIVPVDVHVSRIAKRDYQISANKNHLKELRTKYNALPISRKKINLELDHIRLMLFKKWGSYAGWAQGVLFSKEIGG----TSGSTTTGTIKKRKWDMIKETEAIVTKQMKLKVELSDLHIKEAKID", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9V3I8-1", "uniprot_id": "OGG1_DROME", "id": "Q9V3I8-1", "name": "N-glycosylase/DNA lyase", "aln": "MLAHNLGFHKKRLFSNMKAVLQDRGVIGLSLEECDLERTLLGGQSFRWRSICDGNRTKYGGVVFNTYWVLQQEESFITYEAYGTS-------------------------------------SPLATKDYSSLISDYLRVDFDLKVNQK-DWLSKDDNFVKFLS--KPVRLLSQEPFENIFSFLCSQNNNIKRISSMIEWFCATFGTKIGHFNGADAYTFPTINRFHDIPCEDLNAQLRAAKFGYRAKFIAQTLQEIQKKGGQNWFIS--------LKSMPFEKAREELTLLPGIGYKVADCICLMSMGHLESVPVDIHIYRIAQNYY--LPHLTGQKNVTKKIY-------------EEVSKHFQKLHGKYAGWAQAILFSADLSQ-------------------FQNTSTVACKKKSNKKPKK------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* * .* **:*** * :: . : .*:::*. * * . * * :*:* *:* * ::**:**.**:* ** * : :* :* : ::.. : **. . :. : :** :****::: : : : :. . : : ..:. * *:* *****:***.: :*** *: :**:. * . . . ..: . * ******.:**. :: . * * * ", "identical_positions": 70, "similar_positions": 75, "identity": "16.02%" }, { "cls_id": "homologset.agr.RGD:621169", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R0N9-1", "uniprot_id": "SYT9_MOUSE", "id": "Q9R0N9-1", "name": "Synaptotagmin-9", "aln": "MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLFSGSKDNNQEPLNYTDTETNEQENSEDFLDPPTPCPDSSMKISHTSPDIPLSTQPGGQENCAHAVRVQRQVTEPTPSARHNSIRRQLNLSNPDFNIQQLQRQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVHYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFFDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPESIDQIHLSIAVMDYDRVGHNEVIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLMEKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q925C0-1", "uniprot_id": "SYT9_RAT", "id": "Q925C0-1", "name": "Synaptotagmin-9", "aln": "MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLFSGSKDNNQEPLNYTDTETNEQENSEDFLDPPTPCPDSSMKISHTSPDIPLSTQPGGQDNCAHAVRVQRQVTEPTPSARHNSIRRQLNLSNPDFNIQQLQRQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVHYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFFDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPESIDQIHLSIAVMDYDRVGHNEVIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLLEKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86SS6-1", "uniprot_id": "SYT9_HUMAN", "id": "Q86SS6-1", "name": "Synaptotagmin-9", "aln": "MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPTPCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLVEKR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************************************************************************** ************* ***************************************.* *:****.***********.************************:********************************************************************************************************* *********************************:******************************************************************************************************.********************:***********************************:***", "identical_positions": 478, "similar_positions": 9, "identity": "97.35%" }, { "cls_id": "homologset.agr.RGD:621170", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07936-1", "uniprot_id": "ANXA2_RAT", "id": "Q07936-1", "name": "Annexin A2", "aln": "MSTVHEILCKLSLEGDHSTPPSAYGSVKPYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELPSAMKSALSGHLETVMLGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGEFRKLLVALAKGKRAEDGSVIDYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYFIQQDTKGDYQKALLYLCGGDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07356-1", "uniprot_id": "ANXA2_MOUSE", "id": "P07356-1", "name": "Annexin A2", "aln": "MSTVHEILCKLSLEGDHSTPPSAYGSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07355-1", "uniprot_id": "ANXA2_HUMAN", "id": "P07355-1", "name": "Annexin A2", "aln": "MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NMY6-1", "uniprot_id": "AXA2L_HUMAN", "id": "A6NMY6-1", "name": "Putative annexin A2-like protein", "aln": "MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNIVTNRDNAQRQDIVFSYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDAQDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQRIQNKPLYFADQLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************************.****************:*************:***.*.*****.*:*********.**:***********:******************************************************************:****:******:*****************::************************* ******:**************:**************** **********:********************************************:*********************", "identical_positions": 318, "similar_positions": 19, "identity": "93.81%" }, { "cls_id": "homologset.agr.RGD:621171", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09525-1", "uniprot_id": "ANXA4_HUMAN", "id": "P09525-1", "name": "Annexin A4", "aln": "MATKG-------GTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLIDDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRISQTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P55260-1", "uniprot_id": "ANXA4_RAT", "id": "P55260-1", "name": "Annexin A4", "aln": "METKG-------GTVKAASGFNATEDAQVLRKAMKGLGTDEDAIIGVLACRNTAQRQEIRTAYKSTIGRDLLEDLKSELSSNFEQVILGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRNPEEIRRINQTYQQQYGRSLEEDICSDTSFMFQRVLVSLTAGGRDEGNYLDDALVRQDAQDLYEAGEKRWGTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRNKPAYFAERLYKSMKGLGTDDSTLIRVMVSRAEIDMLDIPANFKRVYGKSLYSFIKGDTSGDYRKVLLILCGGDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97429-1", "uniprot_id": "ANXA4_MOUSE", "id": "P97429-1", "name": "Annexin A4", "aln": "MEAKG-------GTVKAASGFNATEDAQTLRKAMKGLGTDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDLKSELSSNFEQVILGLMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRINQTYQQQYGRSLEEDICSDTSFMFQRVLVSLSAAGRDEGNYLDDALMKQDAQELYEAGEKRWGTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRSKPSYFAERLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRASFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22464-1", "uniprot_id": "ANXB9_DROME", "id": "P22464-1", "name": "Annexin B9", "aln": "MSSAEYYPFKCTPTVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSELGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSLESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRSYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDKTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKEDAETDIGYVLVTLTAW--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : ** .*. *:. *** *******:****.*** :** *. .** ** *:*:: *:**:.******..:**:**:.:*** : .***: *:.* **** .:****.: . *: * * *:*.:*:***.*: .*** *:*: *** ..***.: :*:* *** *::*** :***** .* ::* :*. ::* ::* **:.:* :***::** * ***.*..:****** :.* **:*:*:.** *:**.*.****::***:***: ** *:. ***** *:** *:. * **: * . ", "identical_positions": 156, "similar_positions": 91, "identity": "47.85%" }, { "cls_id": "homologset.agr.RGD:621172", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48037-1", "uniprot_id": "ANXA6_RAT", "id": "P48037-1", "name": "Annexin A6", "aln": "MAKIAQGAMYRGSVHDFADFDANQDAEALYTAMKGFGSDKESILELITSRSNKQRQEICQSYKSLYGKDLIADLKYELTGKFERLIVNLMRPLAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQIHQLVAAYKDAYERDLESDIIGDTSGHFQKMLVVLLQGTRENDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKALLKLCGGDDDAAGQFFPEAAQVAYQMWELSAVSRVELKGTVRAANDFNPDADAKGLRKAMKGIGTDEATIIDIITQRSNVQRQQIRQTFKSHFGRDLMADLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFKRILISLATGNREEGGENRDQAQEDAQVAAEILEIADTPSGDKTSLETRFMTVLCTRSYPHLRRVFQEFIKKTNYDIEHVIKKEMSGDVKDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRVMVSRSEIDLLNIRREFIEKYDKSPHQAIEGDTSGDFMKALLALCGGED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14824-1", "uniprot_id": "ANXA6_MOUSE", "id": "P14824-1", "name": "Annexin A6", "aln": "MAKIAQGAMYRGSVHDFPEFDANQDAEALYTAMKGFGSDKESILELITSRSNKQRQEICQNYKSLYGKDLIEDLKYELTGKFERLIVNLMRPLAYCDAKEIKDAISGVGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLESDIIGDTSGHFQKMLVVLLQGTRENDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKALLKLCGGDDDAAGQFFPEAAQVAYQMWELSAVSRVELKGTVCAANDFNPDADAKALRKAMKGIGTDEATIIDIVTHRSNAQRQQIRQTFKSHFGRDLMADLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKTLIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGNREEGGENRDQAQEDAQVAAEILEIADTPSGDKTSLETRFMTVLCTRSYPHLRRVFQEFIKKTNYDIEHVIKKEMSGDVKDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRVMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFMKALLALCGGED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08133-1", "uniprot_id": "ANXA6_HUMAN", "id": "P08133-1", "name": "Annexin A6", "aln": "MAKPAQGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLKALLALCGGED", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **** ****:***. **.*******************:**::******:****:**.********** ***************.**** **************:******************:****************:***********************:***************************************************************************************************************************************************:****.***************************:******** .***********.*******:**** *****:*:***.******************:*****************************************:****************************************:*********:******* ***:*****************************:****************** ****:**.*********:*************************************:*********************** ************:***********", "identical_positions": 629, "similar_positions": 34, "identity": "93.46%" }, { "cls_id": "homologset.agr.RGD:621173", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07076-1", "uniprot_id": "ANXA7_MOUSE", "id": "Q07076-1", "name": "Annexin A7", "aln": "------------MSYPGYPPTG-------YPPFPG--YPPAGQESSFPTAGQ-YPYP---SGFPPMGGGAYPPAPSGGYPGAGG-YPAPG----GYPAPGGYPGALSPGGPPAYPG---GQGFGAPPGGAGFS-GYPQPPAQSYGGGPAQVPVPGGFPGGQMPSQYPGGQAPYP----------------------SQPASMTQGTQGTILPASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDERQSVNHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIVGQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F6D1-1", "uniprot_id": "F7F6D1_RAT", "id": "F7F6D1-1", "name": "Annexin", "aln": "MPGSSGTPLSVRMSYPGYPPTG-------YPPFPG--YPPAGQESSFPTSGQ-YPYP---SGFPPMGGGAYPPAPSGGYPGAGG-YPSPG----GYPAPGGYPGTLNPGGPPSYPG---GQGFGAPPGGAGFS-GYPQPPAQSYGGGPAQVPVPGGFPGGQMPSQYPGGQSPYPGQIDTESFSSYPAFSPVSLDYSSDPAAMTQGTQGTIRPASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAIQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRELERDIRSDTSGHFERLLVSMCQGNRDESPSINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIVGQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20073-1", "uniprot_id": "ANXA7_HUMAN", "id": "P20073-1", "name": "Annexin A7", "aln": "------------MSYPGYPPTG-------YPPFPG--YPPAGQESSFPPSGQ-YPYP---SGFPPMGGGAYPQVPSSGYPGAGG-YPAPG----GYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFS-GYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIVGQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VXG4-1", "uniprot_id": "ANX11_DROME", "id": "Q9VXG4-1", "name": "Annexin B11", "aln": "-------MYPFGSGMPSHPPTSTNHHEPPRAPFGAGWVPPMQQNSPYPPPSQPHPHSQPSSQMHPQQHQQYPGGAPAPYPPMSAPYPSAAPSYPPYPTSNPYPAQYAPPAHNHYQQ--PSVSNSPYPADRGYTPAMTAGYDAGYGYGNGQGHGQG-HGHGQGHGHGHGQGHEYGHGYGQGYGHGQGHGNGQGHAHRSLPAHR-EGTP-TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIEDIKSETSGNFEKLLVGLLRPIVDYYCAELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRLYGAHLESELKSETSGNFKRLLTSLCTAARDESGRVDPVAAKNDARELLKAGELRVGTDESMFNMILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAGIGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALVGEQRSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.:***. .** . ** *:*.:*...* :*:. * : * ** ... ** .. **:.. **:.. **. * . * . . . *.. *:: . . .** * .* * . ** .: * * * ** : * *: **:****::**. ************:*:::::..***:***:*: *** :*****:*:*** ***:*:*::.*: * . * . .*..*: * **:*.******** :* **. * . * :* .** :::*:***:*:***.*:* . *** :: *::**:.* :*** *:***** *****. *.: **: :: *. *:.:.* .::.:**** * .** :* :*. *:. :**.**: :* * **:*: *:*:::******:.:** * ::* *:* : * .****.*:: * *:**: ", "identical_positions": 193, "similar_positions": 144, "identity": "36.9%" }, { "cls_id": "homologset.agr.RGD:621174", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29692-1", "uniprot_id": "EF1D_HUMAN", "id": "P29692-1", "name": "Elongation factor 1-delta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATNFLAHEKIWFDKFKYDDAERRFYEQMNGPVAGASRQENGASVILRDIARARENIQKSLAG---------SSGPGASS----------GTSGDHGELVVRIASLEVENQSLRGVVQELQQAIS--KLEARLNVLEK--SSPGHRATAPQTQHVSPMRQVEPPAKKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPAL-VAKSSILLDVKPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEEITKFEEHVQSVDIAAFNKI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57776-1", "uniprot_id": "EF1D_MOUSE", "id": "P57776-1", "name": "Elongation factor 1-delta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATNFLAHEKIWFDKFKYDDAERRFYEQMNGPVTSGSRQENGASVILRDIARARENIQKSLAG---------SSGPGASS----------GPGGDHSELIVRITSLEVENQNLRGVVQDLQQAIS--KLEARLSSLEK--SSPTPRATAPQTQHVSPMRQVEPPTKKGATPAEDDEDKDIDLFGSDEEEEDKEAARLREERLRQYAEKKAKKPTL-VAKSSILLDVKPWDDETDMAQLETCVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEEITKFEEHVQSVDIAAFDKI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B7W1-1", "uniprot_id": "A0A8M2B7W1_DANRE", "id": "A0A8M2B7W1-1", "name": "", "aln": "MRNRSHRNSSSNQSGSSERQTDRTTGCLSSGALEGLRSECSAIWFDRVQYERAESLYYVRLLQQQNGTTATASSSSSKRKQDTCQHGEQEACHHIVQSVWVNKPKYDQAESKFVGQNHAATPRSLQLQPSSQTPCDEGYQSQTPTPPTPASKPINGLPCLSLPPMGVWLQKPLFDKAEASFYQNLYNQNSTPRKPTNQSKSKRQNNNVAAPKKPVVCNQQDSNHPSTNQGAAGCYFLHADSERVWLDRGRYAEAESRFYGGAVGRSIKTPVNPSKQKQKKMTAADCLASERIWFDKPRYDEAERRFYEQMNGPTK--PKQDTGANTILQDIARARENIQKSLAGLKTTLQPSRGSAPKPSNPSHCSASSAGGSAADIGELAARMKSLELENQSLHKVVEDLRSALS--KMESRVSALERRSSSSSSSSSAPAVNGTRPAAAQKPPSAP--VKEEEDDDDDIDLFGSD-EEEDEEAERLKEQRLQEYAAKKAKKPAL-IAKSSILLDVKPWDDETDMSKLEECVRSVQMDGLLWGASKLMPVGYGIKKLQINCVVEDDKVGTDFLEEEITKFEDYVQSVDVAAFNKI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z1P2-1", "uniprot_id": "A0A8M6Z1P2_DANRE", "id": "A0A8M6Z1P2-1", "name": "", "aln": "MENQRRPRAKEETRQESTRNLPKSN-------------------------------------DGRRKRTRSSRSENLGSEEEGHSHHDLSSQGNKGEKVWFNRNLYEQADYDYQNLLSAG----------------------------------AGIPPVSSSPKDRIPRTLVFRAKRNGAQQSQDEDHQALTRSYVSRQLQRGSTHYRSSSEP----QKDRQFPKSSR------------KRVFSETER---------------------SPQKKDNITMSGLQGLAQENIWFDKSRYDEAERCFYEGANGIPQ--TSQERDASAILQDIAKARQNIQQSLAGVKTALQGS-KGHTRASKPRERKSSQNASKSEDQSELVSRLKSLELDNKNLHRVVDDLRATLS--KLESRMATLEK---TQAPATKGVTVIKAAPVQKPKVEEHN----GADDEDDDIDLFGSD--EEDEEAERIKAERVKEYSQRKAKKPAL-IAKSSILLDVKPWDDETDMSKLEECVRSVQMDGLLWGASKLVPVGYGIKKLQINCVVEDDKVGTDILEEEITQFEDYVQSVDIAAFNKI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL18-1", "uniprot_id": "EF1D_DROME", "id": "Q9VL18-1", "name": "Probable elongation factor 1-delta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVEALDKFWADKSRYDLAEKRFYE---GPQK--VTDRSHYSPLVSEIAKAREHIQNSLEK---------IDGVTLDD-------------GLNSELAKRLAQLEGEHKELKTQVSLLNELLT--ATVKRLETQLK---LTNGVSKEPEVEAKKPE--------------ANDDDDDVDLFGSDSEEEDGEAARIREERLAAYAAKKAKKVQI-IAKSNIILDVKPWDDETDLKVMETEIRKITQDGLLWGASKFVPVAFGIQKLSISCVVEDDKVSIDWLTEEIEKLEDFVQSVDIAAFNKI------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32471-1", "uniprot_id": "EF1B_YEAST", "id": "P32471-1", "name": "Elongation factor 1-beta", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASTDFSKIETLKQ-LNASLAD------------------------------KSYIEGTAVSQADVTVFKAFQSAYPEFSRWFN--HIASKADEFDS-----FPAASAAAAE--------------------EEEDDDVDLFGSDDEEADAEAEKLKAERIAAYNAKKAAKPAKPAAKSIVTLDVKPWDDETNLEEMVANVKAIEMEGLTWGAHQFIPIGFGIKKLQINCVVEDDKVSLDDLQQSIEEDEDHVQSTDIAAMQKL------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q5PQJ6-1", "uniprot_id": "P5CR3_RAT", "id": "Q5PQJ6-1", "name": "Pyrroline-5-carboxylate reductase 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADEMSEPRRVGFVGAGRMAEAIAQGLIR---AGKVEAKQVLASAPTDKNLCHFRALG----------CQTTHSN--------------HEVLQNCPLVIFATKPQVLPAVLAEVAPVVTTEHIIVSVAAGISLSSMEELLPPKTRVLRVSPNLPCVVQEGAMVMTRGHHAGNEDAKLLQNLLEACGQCIEVPESYVDIHTGLSGSGVAFVCTFSEALAEG-----AIKMGMPSDLAHRIAAQTLLGTAKMLQQEGKHPAQLRTDVLTPAGTTIHGLHALEQGGFRAAAMSAVEAATCRAKELSKK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . :: : : : . .. . . .. ..: : .: * :. .: . : : .. : * : .: : : : * * : . :* . :. ... . . . . *. ** : ", "identical_positions": 8, "similar_positions": 52, "identity": "1.35%" }, { "cls_id": "homologset.agr.RGD:621175", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PTG5-1", "uniprot_id": "E9PTG5_RAT", "id": "E9PTG5-1", "name": "", "aln": "MAADLNLEWICSLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPTGWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNDQTVATMTSEEKKERPISMINEASNYNMASDYTVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQDSTGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIAMLTAEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRITFNFRVDKITTESASTKETNNIPNHRVLIRPEVQNNQKNKEISKIEEKRALEAER------------------------------------------------------------------------------------------------------------------------YGFQKDG-QDRPLTKINSVKLNSLPSEYESGPACPPQNIHYRPINVNNSDSKAVNVSLADVRGGSHPNTGPLATEADRVIQRTNSMQQLEQWIKVQKGRGLEEEPRGVISYQTLPRNMPSHRAQILARYPEGYRTLPRNSKTRPESICSVTPSGHEKT-GPGAEEKRRSMRDDTMWQLYEWQQRQFYHKQSTLPRHSCLSSPKAMGKVSDQTMHSIPTSPSHVPAAAYQGFSPQR----TYRSEVSSPIQRGDVTIDRRHRPHHPKHVYVPDRRSMPAGLALQAVSPQSLHGRTPEELTLLLIKLRRQQAELSSIREHTLAQLMQLKLEAHSPKNEILSHHLQRNTIYLDHQMKENEPIITMVHTMIENSALRPQLYQQFLRQKNKISLYCLSQDECRGTLYKYRPEEVDIDAKLSRLCEQDKVVRALEEKLQQLHKEKYTLEQALLSASQEIEMNADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQDQLDRLGEVQSESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGSSETGLAGPKPFPAVKYKSEEEE--VVPPRPPLPRSYDFTEQPPIIPPLPSDSSSLLCYSRGPVHLPEEKKSHQVQGYPRNGSHCGPDYRLYKSEPELTTVAEVDESNGEEKSEPASEAEAP-VVRGSHFPVG-VPLRTKSPTPESSTIASYVTLRKTKK---MVELRTERPRSAVEQLCL-AESTRPRMTVEEQLERIRRHQQACLREKKK---GLN-VLSASDPSPSQSPSSVRDSPSRVP--QTVRRDDNTKELDAVHRENDGKPD--YDTSAAETAHPEEAEPQSADVGRKLKRTESIFYEMLYTPEPLNGLTSEEVMAKERQEEQVPEGAVCSLQEEAAMANHQAEGPPEE--AESLHEEEE--ALASCEPAPETPRENQ-TTVKSLSPSPDSSTAADPPTPPQLTEGS---HFMCV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q6H8-1", "uniprot_id": "E9Q6H8_MOUSE", "id": "E9Q6H8-1", "name": "", "aln": "MAADLNLEWICSLPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPTGWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNDQTVATMTSEDKKERPISMINEASNYNMASDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQDSTGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIAMLTAEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRITFNFRVDKITTDSASTKETNNIPNHRVLIRPEVQNHQKNKEISKIEEKRALEAER------------------------------------------------------------------------------------------------------------------------YGFQKDG-QDRPLTKINSVKLNSLLSEYESGPDCPPQNVHYRPINVNSSDGKAVNVSLADVRGGSHPNAGPLATEADRVIQRTNSMQQLEQWIKVQKGRGLEEEPRGVISYQTLPRNMPSHRAQILARCPEGYRTLPRNSKTRPESICSVTSSGHEKT-GPGAEEKRRSMRDDTMWQLYEWQQRQFYHKQSTLPRHGCLSSPKAMVQVSDQTMHSIPTSPSHGSAAAYQGFSPQR----TYRSEVTSPIQRGDVTIDRRHRPHHPKHVYVADRRSMPAGLTLQAVSPQSLQGRTPEELTLLLIKLRRQQAELSSVREHTLAQLMQLKLEAHSPKNEILSHHLQRNTIYLDHQMKENEPIITMVHTMIENSALRPQLYQQFLRQKNKISLYCLSQDECRGTLYKYRPEEAGIDAKLSRLCEQDKVVRALEEKLQQLHKEKYTLEQALLSASQEIEMNADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRDQMQGQLDRLGEVQSESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGSSETGLAGSKPFSSVKYKSEEEE--VVPPRPPLPRSYDFTEQPPIIPPLPSDSSSLLCYSRGPVHLPEDKKIHQVQGYPRNGSHCGPDYRLYKSEPELTTVAEVDESNGEEKSEPVSETEAP-VVKGSHFPVG-VPLRTKSPTPESSTIASYVTLRKTKK---MVELRTERPRSAVEQLCL-AESARPRMTVEEQLERIRRHQQACLREKKK---GLS-VLGASDPS------DVRDSPLRLT--QTLRRDDNVKELDTVHRENDVKPD--YETPAAQCAHLEDAEPQNADIGRKLKRSE-----MLYTPEP-NGMASEEVTEKERQKEQVHADGSCSPQEETAMTEHQMEGPPEE--AESLHEEEE--TLASCEPAPEIPRENQ-TTVRSLSPSPDSSTAADPPTPPQLREGS---HFMCV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAU0-1", "uniprot_id": "PKHA5_HUMAN", "id": "Q9HAU0-1", "name": "Pleckstrin homology domain-containing family A member 5", "aln": "MAADLNLEWIS-LPRSWTYGITRGGRVFFINEEAKSTTWLHPVTGEAVVTGHRRQSTDLPTGWEEAYTFEGARYYINHNERKVTCKHPVTGQPSQDNCIFVVNEQTVATMTSEEKKERPISMINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWLYKQDSTGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVK------RVDKITSENAPTKETNNIPNHRVLIKPEIQNNQKNKEMSKIEEKKALEAEK------------------------------------------------------------------------------------------------------------------------YGFQKDG-QDRPLTKINSVKLNSLPSEYESGSACPAQTVHYRPINLSSSENKIVNVSLADLRGGNRPNTGPLYTEADRVIQRTNSMQQLEQWIKIQKGRGHEEETRGVISYQTLPRNMPSHRAQIMARYPEGYRTLPRNSKTRPESICSVTPSTHDKTLGPGAEEKRRSMRDDTMWQLYEWQQRQFYNKQSTLPRHSTLSSPKTMVNISDQTMHSIPTSPSHGSIAAYQGYSPQR----TYRSEVSSPIQRGDVTIDRRHRAHHPKHVYVPDRRSVPAGLTLQSVSPQSLQGKT-------------------------------------------------------------------------------------------------LSQDEGRGTLYKYRPEEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADNPAAIQTVVLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHLGEVQTESAGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNE-----------------------------------------------------------------GPDYRLYKSEPELTTVAEVDESNGEEKSEPVSEIETS-VVKGSHFPVGVVPPRAKSPTPESSTIASYVTLRKTKK---MMDLRTERPRSAVEQLCL-AESTRPRMTVEEQMERIRRHQQACLREKKK---GLN-VIGASDQSPLQSPSNLRDNPFRTT--QTRRRDD--KELDTAIRENDVKPD--HETPATEIVQLKETEPQNVDFSKELKKTENISYEMLFEPEP-NGVNSVEMMDKERNKDKMPEDVTFSPQDETQTANHKPEEHPEENTKNSVDEQEE--TVISYESTPEVSRGNQTMAVKSLSPSPESSASPVPSTQPQLTEGS---HFMCV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBV2-1", "uniprot_id": "A0A8M2BBV2_DANRE", "id": "A0A8M2BBV2-1", "name": "", "aln": "MAADLNPDWLSCLPSSWSYGVTRDGRVFFINEEAKSTTWLHPVTGEAVITGHR-KTPDLPTGWEEGYTFEGARCFINHNERKVTCKHPVSGVPSQDNCIFVVNEQPATKAPEAEKKERPTSTMSEASNYTGGSDYTTHPSSPTTRPSRSSKKVHNFGKRSNSIKRNPNAPVIKNGWLHKQDSTGMKMWKKRWFVLSDMCLFYYRDEKEEGILGSILLPSFHISMLSVDDHITRKYAFKATHPNMRTYYFSTDTAKDMESWMKVMSDAAMAHSEPIR------RLEKVKLDSRVPQEMNNMLNHRVLTRPEIQNNERNRETLRQEDKKSKPSEKPQKDKDRVSMQKDGERFSENYTHRQKDGERYMLQKDLEKFVLQKDGEKYAVQKEGDKYLLQKDGHKYTVHKDGDKYTLQRELEMYNPPKDAEKIPQKDARFSLVQKELEKPVPPPRSEEKYGFQKEGTIERPLTKINSIKLQPAQAAAIAAAVSSSRMMQKQVNGSGERAGDRSPGDLSTVRTSVPPPTQP-APEPERSLSRTSSMQQLEQWVRTHRTRAPDDDTRSITSYQTLPRNMPSHRAQIVPRYPEGYRTLPRN-MLRPDSICSVAGSVYDRALQPSTQEKRRSIRDDTMWQLYEWQQRQAHSRLG----YGTLPSPKTMG----QIAESIPTSPSHGSLAGYHTFSPNRPLNPDSRSELSSPVFRGDVTIERRHRPHLSKYSYPAERRAAPP---AQNITAQSLQGKTPEELTLLLIKLRRQQAELNSLREHTLAQLMQLNLDATNPKSEILSHHLQRNLMYLDSQMKENEPIIFMIHTMIENSAPRPQLYQQQ-----------MSPEEYRENTYMYRPEELDVDAKLSRLCEQDKVVRTQEEKLQQLHREKHTLETALLSASQEIEMSSENPAAVQSVVQQRDVLQSGLLSTCRELSRVSTELERSWREYDRLEADVTLAKTNLLEQLEALGSPQTEPPSQKHVQIQKELWRIQDVMEALSKNKPKR-NPEPSFPGANPLSTLHKSEDSVDSSCVPPRPPLPYSYEGGDRPPPLP-----NPGQPHTTRTTPHRPEDRKTAQ-----RNGTHTGPDYRLYKSEPELTTVAEVDESNGEDKSEQTAEKEPPGVTKGIVYPVGVVSPRTKSPMPESSTIASYVTLRKTKKPDPRTCQPQDRPRSAVEQMSSGAEVGRTRMSVEEQMERIRRHQQGALRERRREDGSLSRSLSFTKDSTYYTLQARKKSPVISPDEQDERRDMTPVERDTKHTKHPDAEENCRDTKEQLPAHTHLEIKDKASVTRSVSMKES----LLKSVSPKPVLKQDESECKLEYDRKLATQNSLQTAVMVRVGTEEDEEDEEEEQKDSVQQQEDSYELSNSKHSTLISASCDRKNTSSPSSSSDWKSRPLLHQLPNTNTTASRPQFNSD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** :*:. ** **:**:**.************************:**** ::.********.******* :**************:* ***********:*..:. .. :***** * :.*****. ***:.** **. *.**:**********************::.***:********:**********:**********************:*::*: :***.*******:*********.***.*:** ***.* ***:.::**:: *::*:. :. .:* **: ***** :**:**:::*:* : *:*:: :*: *****:* :********:**:. : :.. ...: :: : . .. .. .*: :* . * : * .*.:* :.**.********:: :: *. :::.*.: ****************:.* ********** **:*****: * :::: *.::*****:*************** : : . :. *.***:* * .******** . *.*: :**:* ***::**: ******:****.* .*: * .:**: *. * ::.***:*:* :* :* * . * ***** .:**************:: ********:**:*** *********** ::****:*:** *** **.***********.::****:*****:** ***::: :: **: **. *:*... ::.**************.***:* :* ..* .: *.:*:.::: ..: *************************:*** .:* *.. *.:* :*** *. *:*** ***************** :********:. ** *.**:****:********..***::: .*. :. :. * :..* . * *** * *: :: : :* .: . :.... :.:. .* :* .* : . * * . . :: . . .: * ** :*:.::*: : . : :. . : . * *.*.: .: . *: : :* . ", "identical_positions": 584, "similar_positions": 292, "identity": "40.81%" }, { "cls_id": "homologset.agr.RGD:621176", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07308-1", "uniprot_id": "ACOD1_RAT", "id": "P07308-1", "name": "Acyl-CoA desaturase 1", "aln": "-----------------------------------MPAHMLQ-EISSSYTTTTTITEPPSGNLQNGREKMKKVPLYLEED---IRPEMREDIHDPSYQDE--EGPPPKLEYVWRNIILMALLHVGALYGITLIPS--SKVYTLLWGIFYYLISALGITAGAHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFLHSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHAFPYDYSASEYR-WHINFTTFFIDCMAALGLAYDRKKVSKAAVLARIKRTGDGSHKSS------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P13516-1", "uniprot_id": "ACOD1_MOUSE", "id": "P13516-1", "name": "Acyl-CoA desaturase 1", "aln": "-----------------------------------MPAHMLQ-EISSSYTTTTTITAPPSG---NEREKVKTVPLHLEED---IRPEMKEDIHDPTYQDE--EGPPPKLEYVWRNIILMVLLHLGGLYGIILVPS--CKLYTCLFGIFYYMTSALGITAGAHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYHHTFPFDYSASEYR-WHINFTTFFIDCMAALGLAYDRKKVSKATVLARIKRTGDGSHKSS------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00767-1", "uniprot_id": "SCD_HUMAN", "id": "O00767-1", "name": "Stearoyl-CoA desaturase", "aln": "-----------------------------------MPAHLLQDDISSSYTTTTTITAPPSRVLQNGGDKLETMPLYLEDD---IRPDIKDDIYDPTYKDK--EGPSPKVEYVWRNIILMSLLHLGALYGITLIPT--CKFYTWLWGVFYYFVSALGITAGAHRLWSHRSYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLMMCFILPTLVPWYFWGETFQNSVFVATFLRYAVVLNATWLVNSAAHLFGYRPYDKNISPRENILVSLGAVGEGFHNYHHSFPYDYSASEYR-WHINFTTFFIDCMAALGLAYDRKKVSKAAILARIKRTGDGNYKSG------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QG70-1", "uniprot_id": "F1QG70_DANRE", "id": "F1QG70-1", "name": "stearoyl-CoA 9-desaturase", "aln": "---------------------------------------MPDSDVK-----APVLQP---------------------------QLEAMEDEFDPLYKEK--PGPKPPMKIVWRNVILMSLLHIAAVYGLFLIPS--AHPLTLLWAFACFVYGGLGITAGVHRLWSHRSYKATLPLRIFLAIGNSMAFQNDIYEWSRDHRVHHKYSETDADPHNSNRGFFFSHVGWLLVRKHPEVIERGRKLELTDLKADKVVMFQRRFYKLSVVLMCFVVPTVVPCYMWGESLWIAYFIPTLLRYALGLNSTWLVNSAAHMWGNRPYDGNIGPRENRFVTFSAIGEGYHNYHHTFPYDYSTSEYG-WKLNLTTIFVDTMCFLGLASNRKRVSKELILARVKRTGDGSYRSG------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B301-1", "uniprot_id": "A0A8M2B301_DANRE", "id": "A0A8M2B301-1", "name": "stearoyl-CoA 9-desaturase", "aln": "---------------------------------------MVASQARRQYTSTEAMAD---------------------------VTTTTEDVFDDSYVEK--PGPSPPVQIVWRNVILMTLLHLGALYGMTILPF--VSSLTLIWTGVCFMVSALGITAGAHRLWSHRSYRASLPLRIFLAVANSMAFQNDIYEWARDHRVHHKFSETDADPHNARRGFFFAHIGWLLVRKHPEVIDKGRKLTFEDLKADSVVMFQRRHYKLSVVVMCFLIPTLVPWFFWEESLWTAYLVPCLLRYAVVLNATWLVNSAAHMWGMRPYDHNINPRENKFVAFSAIGEGFHNYHHTFPHDYATSEFG-SRLNVTKAFIDLMCFLGLANDCRRVTHETILARVQRTGDGSHKSG------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA94-1", "uniprot_id": "Q9VA94_DROME", "id": "Q9VA94-1", "name": "Fatty acid desaturase domain-containing protein", "aln": "----MGHLSTSERVCSKTPAIATDSSPPLVARRSKFPNGDAQQQVRRGEDSSPELPPRGKLQLPPKREELPRSVVPKEIANHVPKDAIDLEEYTRTFVGDRVLGWQFQAPLKWDKVIQISLLHIVAGICLLTYPLRELNPYTTIWSFFVGGVAGFGVTAGAHRFWTHKSYKANTVLRSILMVCYCVAGQNTLYDWVRDHRVHHKYSETDADPHNANRGFFFSHVGWLMMLKHPEVLRRGRQIDMSDILADPVVRFHQKYFIPLKTFFCFILPTVIPVYCWGETWTLAFIQQCLFRYVSSLNFTWSVNSAAHLWGSRPYDKRIMPSENIYVSLLAMGEGWHNYHHVFPWDYKAAELGNYTVNFTTMVLDAFHKLGWAWNMKQPSKELVRRTLEKYGDGTHASQLGGPEE-----------FKDGVLAGATMVGHVHYAEVPDPELEYDAESSSTESAKLDENENEGERMKKSKKAAN----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTD4-1", "uniprot_id": "Q9VTD4_DROME", "id": "Q9VTD4-1", "name": "", "aln": "-------------------------------------------MPRNTKDTTGVLYESD-------------------------VETVDGGLSTELSNRKTTDGS--KLELVWVNIVLFVILHISSLYGVWLLFTS-ATWTTVVLFWPTVVVTILGVSGGAHRLWAHRTFKANTPLKLIFLFLNTLAFQDAVYYWARDHRVHHKYTETDADPYNSQRGWFFAHIGWLCCRKHPEVVEKGKQIDLSDLEADPLIMFQKKYYLLLMPIICFVLPTVLPMYLWGESLNVSWHVMALLRWCLSLNLIWTVNSSAHMHGMRPYDKNICPVDQGFLIFFRVGEGYHNYHHVFPWDYKSAELGKYSQDVTTKFIEFMAYLGWAYDLKSVSLDLVKQRVQRSGDGS------------------------------------------HPVWGWGDKDQLKEDVGVTTITHQRNEK------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG68-1", "uniprot_id": "Q9VG68_DROME", "id": "Q9VG68-1", "name": "", "aln": "-----------------------------------MAPYSRIYHQDKSSRETGVLFEDD-------------------------AQTVDGDLTTDRFQLKRAEKR--RLPLVWRNIILFALVHLAALYGLHSIFTR-AKLATTLFAAGLYIIGMLGVTAGAHRLWAHRTYKAKWPLRLLLVIFNTIAFQDAVYHWARDHRVHHKYSETDADPHNATRGFFFSHVGWLLCKKHPDIKEKGRGLDLSDLRADPILMFQRKHYYILMPLACFVLPTVIPMVYWNETLASSWFVATMFRWCFQLNMTWLVNSAAHKFGNRPYDKTMNPTQNAFVSAFTFGEGWHNYHHAFPWDYKTAEWGCYSLNITTAFIDLFAKIGWAYDLKTVAPDVIQRRVLRTGDGS------------------------------------------HELWGWGDKDLTAEDARNVLLVDKSR--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFX5-1", "uniprot_id": "Q9VFX5_DROME", "id": "Q9VFX5-1", "name": "Fatty acid desaturase domain-containing protein", "aln": "------------------------MSPNIIGSTFILAETAIADGNNNKMAATPAASAAP-------------------------SAATPSQKVAKKAEAKTPENKPYELEIVWRNVGLFVILHSMALYGLYLVFAE-SAYWELLPVYATMFLGGLGITAGVHRLWSHKAYKAKLPLRIFLMLCQSLAFQNSIWEWTRDHRVHHKFTDTHADPHNSRRGFFFAHMGWLMCKKHPDVTSKGKQISMEDIEQDPVVMFQKKMYFVVMPICCFALPMIFPYYVMGSSLRVCFFTCSMLRFCLSLHFTWLVNSAAHFYGMKPYDVNVSAMNNKLVSTLTIGEGWHNYHHVFPWDYKAAELGTYSFNWTTAFIDVMAKIGQAYDLKFVSQEMVYKRVLRTGDGSHIAALLDANN-----------NSA--IPTSELVAHLDHEKEEHAIWGWDDKDISEEDRKGANVVNKESECKLD---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA92-1", "uniprot_id": "Q9VA92_DROME", "id": "Q9VA92-1", "name": "Fatty acid desaturase domain-containing protein", "aln": "MCLSSPIPGQKQATSVGHCNGSCSLDRNGNRSAAIVPNGGELKHRGHATDATSHTLVKDDDNLGYKEENAVYKE----------QQLLQQQDQTLKEAEQVEEEEEYHPQIRWPDLGAQAFLHIGALYGLYQLFY--ANFYTFLWVVVTVWVSGIGITAGAHRLWSHKSYTASLPLRILLAFAFSIAGQRDAYTWALDHRIHHKFSETDADPHNAKRGFFFAHVGWLFLTPHPKVVAKRKVIDMSDLEADAVCMFQRKYYIPLFALCSIILPVAVPWYFWNEDLWMSFWINFNMRFTWTLNVAFFVNSVAHMYGNKPYDKNLMSTEAPIVSLLAMGEGWHNYHHVFPWDYKTGEFGNYSLNITTGFIDFCAWLGLAKGRKSVSPDMVLRRAKKCGDGTRFLD--------------------------------DDHAHKDPVWGFGDKDIPREDIVELAKMQN----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA93-1", "uniprot_id": "Q9VA93_DROME", "id": "Q9VA93-1", "name": "Fatty acid desaturase domain-containing protein", "aln": "-----------------------------------------------------------------------------------------METTKVKEPDQSGDSIHKKRDAIWPLVLFYIHLNILGVYGIYVLLTS-ASWATILFTALLTLLGTLGVTVGVHRLWAHRTFTASKPLKVFLMFCQTTAGQGSIYSVVQAHRLHHAKFQQDEDPYYSKHSFMYAQVRGGLLKYSPQQEELLKDVDMSDLESDPVVMFQKRFYVLLYIFLNVLLSVNTPFQYFGDSLATSMFVGFWLRSLIVINLGNLVHSSHFIWS---IHKGFKPTDSNSIFLITKSY-WPQYHYLLPRDYQSGEYGNYASGIGSSMIRVFAALDWAKDLKTIGSVAVRQGLTKAVETG------------------------------------------RPIVECIEEQVELEENALPANHFLNREKFM----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21147-1", "uniprot_id": "ACO1_YEAST", "id": "P21147-1", "name": "Acyl-CoA desaturase 1", "aln": "MPTSGTTIELIDDQFPKDDSASSGIVDEVDLTEANILATGLNKKAPRIVNGFGSLMGSKEMVSVEFDKKGNEKKSNLDRLLEKDNQEKEEAKTKIHISEQPWTLNNWHQHLNWLNMVLVCGMPMIGWYFALSGKVP-LHLNVFLFSVFYYAVGGVSITAGYHRLWSHRSYSAHWPLRLFYAIFGCASVEGSAKWWGHSHRIHHRYTDTLRDPYDARRGLWYSHMGWMLLKPNPKYKAR---ADITDMTDDWTIRFQHRHYILLMLLTAFVIPTLICGYFFNDYMG-GLIYAGFIRVFVIQQATFCINSLAHYIGTQPFDDRRTPRDNWITAIVTFGEGYHNFHHEFPTDYRN-AIKWYQYDPTKVIIYLTSLVGLAYDLKKFSQNAIEEALIQQEQKKINKKKAKINWGPVLTDLPMWDKQTFLAKSKENKGLVIISGIVHDVSGYISEHPGGETLIKTALGKDATKAFSGGVYRHSNAAQNVLADMRVAVIKESKNSAIRMASKRGEIYETGKFF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : : . : ..:: * **:*:*::: * *: : . : : ** ** : **: : :. :::: * : *: : *::: : . . :. . :* : ::* . . . . : . : ::*: :* ** . . .: :. * . : : : : ", "identical_positions": 24, "similar_positions": 66, "identity": "4.65%" }, { "cls_id": "homologset.agr.RGD:621177", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1QG70-1", "uniprot_id": "F1QG70_DANRE", "id": "F1QG70-1", "name": "stearoyl-CoA 9-desaturase", "aln": "-----------------------------------MPDSDVK-----APVLQPQLEA-------------------------------MEDEFDPLYKEK--PGPKPPMKIVWRNVILMSLLHIAAVYGLFLIPS--AHPLTLLWAFACFVYGGLGITAGVHRLWSHRSYKATLPLRIFLAIGNSMAFQNDIYEWSRDHRVHHKYSETDADPHNSNRGFFFSHVGWLLVRKHPEVIERGRKLELTDLKADKVVMFQRRFYKLSVVLMCFVVPTVVPCYMWGESLWIAYFIPTLLRYALGLNSTWLVNSAAHMWGNRPYDGNIGPRENRFVTFSAIGEGYHNYHHTFPYDYSTSEYG-WKLNLTTIFVDTMCFLGLASNRKRVSKELILARVKRTGDGSYRSG------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B301-1", "uniprot_id": "A0A8M2B301_DANRE", "id": "A0A8M2B301-1", "name": "stearoyl-CoA 9-desaturase", "aln": "-----------------------------------MVASQARRQYTSTEAMADVTTT-------------------------------TEDVFDDSYVEK--PGPSPPVQIVWRNVILMTLLHLGALYGMTILPF--VSSLTLIWTGVCFMVSALGITAGAHRLWSHRSYRASLPLRIFLAVANSMAFQNDIYEWARDHRVHHKFSETDADPHNARRGFFFAHIGWLLVRKHPEVIDKGRKLTFEDLKADSVVMFQRRHYKLSVVVMCFLIPTLVPWFFWEESLWTAYLVPCLLRYAVVLNATWLVNSAAHMWGMRPYDHNINPRENKFVAFSAIGEGFHNYHHTFPHDYATSEFG-SRLNVTKAFIDLMCFLGLANDCRRVTHETILARVQRTGDGSHKSG------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13011-1", "uniprot_id": "SCD2_MOUSE", "id": "P13011-1", "name": "Stearoyl-CoA desaturase 2", "aln": "-----------------------------------MPAHILQ-EISGAYSATTTITAPPSGGQQNGGEKFEKSSHHWGAD---VRPELKDDLYDPTYQDD--EGPPPKLEYVWRNIILMALLHLGALYGITLVPS--CKLYTCLFAYLYYVISALGITAGAHRLWSHRTYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFVLPTLVPWYCWGETFVNSLCVSTFLRYAVVLNATWLVNSAAHLYGYRPYDKNISSRENILVSMGAVGEGFHNYHHAFPYDYSASEYR-WHINFTTFFIDCMALLGLAYDRKRVSRAAVLARIKRTGDGSCKSG------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P7B9-1", "uniprot_id": "SCD2_RAT", "id": "Q6P7B9-1", "name": "Stearoyl-CoA desaturase 2", "aln": "-----------------------------------MPAHILQ-EISGSYSATTTITAPPSGGQQNGGEKFEKNPHHWGAD---VRPEIKDDLYDPSYQDE--EGPPPKLEYVWRNIVLMALLHIGALYGITLVPS--CKVYTCLFAYLYYVISALGITAGAHRLWSHRTYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGETFVNSLCVSTFLRYAVVLNATWLVNSAAHLYGYRPYDKNISSRENILVSMGAVGEGFHNYHHAFPYDYSASEYR-WHINFTTFFIDCMALLGLAYDRKRVSKAAVLARIKRTGEESCKSG------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O00767-1", "uniprot_id": "SCD_HUMAN", "id": "O00767-1", "name": "Stearoyl-CoA desaturase", "aln": "-----------------------------------MPAHLLQDDISSSYTTTTTITAPPSRVLQNGGDKLETMPLYLEDD---IRPDIKDDIYDPTYKDK--EGPSPKVEYVWRNIILMSLLHLGALYGITLIPT--CKFYTWLWGVFYYFVSALGITAGAHRLWSHRSYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLMMCFILPTLVPWYFWGETFQNSVFVATFLRYAVVLNATWLVNSAAHLFGYRPYDKNISPRENILVSLGAVGEGFHNYHHSFPYDYSASEYR-WHINFTTFFIDCMAALGLAYDRKKVSKAAILARIKRTGDGNYKSG------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VA94-1", "uniprot_id": "Q9VA94_DROME", "id": "Q9VA94-1", "name": "Fatty acid desaturase domain-containing protein", "aln": "----MGHLSTSERVCSKTPAIATDSSPPLVARRSKFPNGDAQQQVRRGEDSSPELPPRGKLQLPPKREELPRSVVPKEIANHVPKDAIDLEEYTRTFVGDRVLGWQFQAPLKWDKVIQISLLHIVAGICLLTYPLRELNPYTTIWSFFVGGVAGFGVTAGAHRFWTHKSYKANTVLRSILMVCYCVAGQNTLYDWVRDHRVHHKYSETDADPHNANRGFFFSHVGWLMMLKHPEVLRRGRQIDMSDILADPVVRFHQKYFIPLKTFFCFILPTVIPVYCWGETWTLAFIQQCLFRYVSSLNFTWSVNSAAHLWGSRPYDKRIMPSENIYVSLLAMGEGWHNYHHVFPWDYKAAELGNYTVNFTTMVLDAFHKLGWAWNMKQPSKELVRRTLEKYGDGTHASQLGGPEEFKDGVLAGATMVGHVHYAEVPDPELEYDAESSSTESAKLDENENEGERMKKSKKAAN---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA92-1", "uniprot_id": "Q9VA92_DROME", "id": "Q9VA92-1", "name": "Fatty acid desaturase domain-containing protein", "aln": "----MCLSSPIPGQKQATSVGHCNGSCSLDRNGNRSAAIVPNGGELKHRGHATDATSHTLVKDDDNLGYKEENAVYKEQQ------LLQQQDQTLKEAEQVEEEEEYHPQIRWPDLGAQAFLHIGALYGLYQLFY--ANFYTFLWVVVTVWVSGIGITAGAHRLWSHKSYTASLPLRILLAFAFSIAGQRDAYTWALDHRIHHKFSETDADPHNAKRGFFFAHVGWLFLTPHPKVVAKRKVIDMSDLEADAVCMFQRKYYIPLFALCSIILPVAVPWYFWNEDLWMSFWINFNMRFTWTLNVAFFVNSVAHMYGNKPYDKNLMSTEAPIVSLLAMGEGWHNYHHVFPWDYKTGEFGNYSLNITTGFIDFCAWLGLAKGRKSVSPDMVLRRAKKCGDGTRFLD---------------------------------DDHAHKDPVWGFGDKDIPREDIVELAKMQN---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTD4-1", "uniprot_id": "Q9VTD4_DROME", "id": "Q9VTD4-1", "name": "", "aln": "-----------------------------------MPRNTKDTTGVLYESDVETVDG-----------------------------GLSTELSNRKTTDG------SKLELVWVNIVLFVILHISSLYGVWLLFTS-ATWTTVVLFWPTVVVTILGVSGGAHRLWAHRTFKANTPLKLIFLFLNTLAFQDAVYYWARDHRVHHKYTETDADPYNSQRGWFFAHIGWLCCRKHPEVVEKGKQIDLSDLEADPLIMFQKKYYLLLMPIICFVLPTVLPMYLWGESLNVSWHVMALLRWCLSLNLIWTVNSSAHMHGMRPYDKNICPVDQGFLIFFRVGEGYHNYHHVFPWDYKSAELGKYSQDVTTKFIEFMAYLGWAYDLKSVSLDLVKQRVQRSGDGSHPVWGWG------------------------------DKDQLKEDVGVTTITHQRNEK------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG68-1", "uniprot_id": "Q9VG68_DROME", "id": "Q9VG68-1", "name": "", "aln": "---------------------------MAPYSRIYHQDKSSRETGVLFEDDAQTVDG-----------------------------DLTTDRFQLKRAEK------RRLPLVWRNIILFALVHLAALYGLHSIFTR-AKLATTLFAAGLYIIGMLGVTAGAHRLWAHRTYKAKWPLRLLLVIFNTIAFQDAVYHWARDHRVHHKYSETDADPHNATRGFFFSHVGWLLCKKHPDIKEKGRGLDLSDLRADPILMFQRKHYYILMPLACFVLPTVIPMVYWNETLASSWFVATMFRWCFQLNMTWLVNSAAHKFGNRPYDKTMNPTQNAFVSAFTFGEGWHNYHHAFPWDYKTAEWGCYSLNITTAFIDLFAKIGWAYDLKTVAPDVIQRRVLRTGDGSHELWGWG------------------------------DKDLTAEDARNVLLVDKSR--------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA93-1", "uniprot_id": "Q9VA93_DROME", "id": "Q9VA93-1", "name": "Fatty acid desaturase domain-containing protein", "aln": "-----------------------------------------------------------------------------------------METTKVKEPDQSGDSIHKKRDAIWPLVLFYIHLNILGVYGIYVLLTS-ASWATILFTALLTLLGTLGVTVGVHRLWAHRTFTASKPLKVFLMFCQTTAGQGSIYSVVQAHRLHHAKFQQDEDPYYSKHSFMYAQVRGGLLKYSPQQEELLKDVDMSDLESDPVVMFQKRFYVLLYIFLNVLLSVNTPFQYFGDSLATSMFVGFWLRSLIVINLGNLVHSSHFIWS---IHKGFKPTDSNSIFLITKSY-WPQYHYLLPRDYQSGEYGNYASGIGSSMIRVFAALDWAKDLKTIGSVAVRQGLTKAVETGRPIVECI------------------------------EEQVELEENALPANHFLNREKFM----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21147-1", "uniprot_id": "ACO1_YEAST", "id": "P21147-1", "name": "Acyl-CoA desaturase 1", "aln": "MPTSGTTIELIDDQFPKDDSASSGIVDEVDLTEANILATGLNKKAPRIVNGFGSLMGSKEMVSVEFDKKGNEKKSNLDRLLEKDNQEKEEAKTKIHISEQPWTLNNWHQHLNWLNMVLVCGMPMIGWYFALSGKVP-LHLNVFLFSVFYYAVGGVSITAGYHRLWSHRSYSAHWPLRLFYAIFGCASVEGSAKWWGHSHRIHHRYTDTLRDPYDARRGLWYSHMGWMLLKPNPKYKAR---ADITDMTDDWTIRFQHRHYILLMLLTAFVIPTLICGYFFNDYMG-GLIYAGFIRVFVIQQATFCINSLAHYIGTQPFDDRRTPRDNWITAIVTFGEGYHNFHHEFPTDYRN-AIKWYQYDPTKVIIYLTSLVGLAYDLKKFSQNAIEEALIQQEQKKINKKKAKINWGPVLTDLPMWDKQTFLAKSKENKGLVIISGIVHDVSGYISEHPGGETLIKTALGKDATKAFSGGVYRHSNAAQNVLADMRVAVIKESKNSAIRMASKRGEIYETGKFF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : : . . : ..:: * **:*:*::: * *: : . : : ** ** : **: : :. :::: * : *: : *:::.: . .::.. : : . :* : ::* . . . . : . : ::*: :* ** . . .: :. * . : : : : ", "identical_positions": 24, "similar_positions": 72, "identity": "4.65%" }, { "cls_id": "homologset.agr.RGD:621178", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PDV7-1", "uniprot_id": "RL10_RAT", "id": "Q6PDV7-1", "name": "Large ribosomal subunit protein uL16", "aln": "MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZWV3-1", "uniprot_id": "RL10_MOUSE", "id": "Q6ZWV3-1", "name": "Large ribosomal subunit protein uL16", "aln": "MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P27635-1", "uniprot_id": "RL10_HUMAN", "id": "P27635-1", "name": "Large ribosomal subunit protein uL16", "aln": "MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPSRGPLDKWRALHS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZV96-1", "uniprot_id": "RL10_DANRE", "id": "Q7ZV96-1", "name": "Large ribosomal subunit protein uL16", "aln": "MGRRPARCYRYCKNKPYPKSRFCRGVPDPKIRIFDLGRKKAKVDEFPLCAHMVSDEYEQLSSEALEAARICANKYMVKTCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSVRTKAQNKEHVIEALRRAKFKFPGRQKIHVSKKYGFTKFNTCDFDNMLAEKRLIPDGCGVKYIPSRGPLSRWKALHAN------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O61231-1", "uniprot_id": "RL10_DROME", "id": "O61231-1", "name": "Large ribosomal subunit protein uL16", "aln": "MGRRPARCYRYCKNKPYPKSRFCRGVPDPKIRIFDLGRKKATVEDFPLCVHLVSDEYEQLSSEALEAGRICCNKYLVKYCGKDQFHIRMRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVRIGQPIMSVRSSDRYKAQVIEALRRAKFKFPGRQKIYVSKKWGFTKYERERYEELRDDNRLEPDGCNVKYRPEHGPIAAWEKAQRDVYA---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P41805-1", "uniprot_id": "RL10_YEAST", "id": "P41805-1", "name": "Large ribosomal subunit protein uL16", "aln": "MARRPARCYRYQKNKPYPKSRYNRAVPDSKIRIYDLGKKKATVDEFPLCVHLVSNELEQLSSEALEAARICANKYMTTVSGRDAFHLRVRVHPFHVLRINKMLSCAGADRLQQGMRGAWGKPHGLAARVDIGQIIFSVRTKDSNKDVVVEGLRRARYKFPGQQKIILSKKWGFTNLDRPEYLKKREAGEVKDDGAFVKFLSKKGSLENNIREFPEYFAAQA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.********* *********: *.***.****:***:***.*::**** *:**:* **********.***.***:.. .*:* **:*:*:*****:*************** *****:***:* .*** *** *:*:*:. * *:*.****::****:*** :***:***: : : . .: **. **: ..:*.: ", "identical_positions": 127, "similar_positions": 49, "identity": "57.47%" }, { "cls_id": "homologset.agr.RGD:621179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47963-1", "uniprot_id": "RL13_MOUSE", "id": "P47963-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMILKPHFHKDWQQRVDTWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRN-VYKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41123-1", "uniprot_id": "RL13_RAT", "id": "P41123-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMILKPHFHKDWQQRVDTWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKMARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRN-VYKKEKARAITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26373-1", "uniprot_id": "RL13_HUMAN", "id": "P26373-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMVLKPHFHKDWQRRVATWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVRCPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPRRRNKSTESLQANVQRLKEYRSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPVRN-VYKKEKARVITEEEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q90Z10-1", "uniprot_id": "RL13_DANRE", "id": "Q90Z10-1", "name": "Large ribosomal subunit protein eL13", "aln": "MAPSRNGMILNPHFHKDWQKRVRTWFNQPARKIRRRKARQAKARRIAPRPVSGPLRPVVRCPTIRYHTKVRAGRGFTLEELKAAGINKKVARTIGISVDSRRRNRSTESLQANVQRLKEYRTKLIIFPRKAAKPKKGDSTEEELKMATQLTGPVMPIKK-VHKKEKARVISEDEKNFKAFASLRMARANARLFGIRAKRAKEAAE-QDVEK---KK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41126-1", "uniprot_id": "RL13_DROME", "id": "P41126-1", "name": "Large ribosomal subunit protein eL13", "aln": "MGKG-NNMIPNQHYHKWWQRHVKTWFNQPARKVRRHANRVKKAKAVFPRPASGALRPVVRCPTIRYHTKLRAGRGFTLEELKGAGIGANFAKTIGIAVDRRRKNKSLESRQRNIQRLKEYRSKLILFPINEKKIRAGESSLEECKLATQLKGPVLPIKNEQPAVVEFREVTKDEKKFKAFATLRKARTDARLVGIRAKRAKEAAESEDAAKGDPKKAKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12690-1", "uniprot_id": "RL13A_YEAST", "id": "Q12690-1", "name": "Large ribosomal subunit protein eL13A", "aln": "MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARATRAAKIAPRPLD-LLRPVVRAPTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQNRNQEIFDANVQRLKEYQSKIIVFPRN------GKAPEAEQVLSAAAT---FPIAQ-PATDVEARAVQDNGE--SAFRTLRLARSEKKFRGIREKRAREKAE-AEAEK---KK---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40212-1", "uniprot_id": "RL13B_YEAST", "id": "P40212-1", "name": "Large ribosomal subunit protein eL13B", "aln": "MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARAARAAKIAPRPLD-LLRPVVRAPTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQNRNQEIFDANVQRLKEYQSKIIVFPRD------GKAPEAEQVLSAAAT---FPIAQ-PATDVEARAVQDNGE--SAFRTLRLARSEKKFRGIREKRAREKAE-AEAEK---KK---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * : : *::* **.:* . *:*..:*: *: * :* : *** . :**:**.**::*: *:******:* *:: **: *:****:** **:*:. * : *:******::*:*:** . *.:. * ::: . :*: : : * : .: : .** :** **:: :: *** ***:* ** :. * ** ", "identical_positions": 78, "similar_positions": 65, "identity": "35.62%" }, { "cls_id": "homologset.agr.RGD:621180", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P36105-1", "uniprot_id": "RL14A_YEAST", "id": "P36105-1", "name": "Large ribosomal subunit protein eL14A", "aln": "MSTDSIVKASNWRLVEVGRVVLIKKGQSAGKLAAIVEIIDQKKVLIDGPKAGVPRQAINLGQVVLTPLTFALPRGARTATVSKKWAAAAVCEKWAASSWAKKIAQRERRAALTDFERFQVMVLRKQKRYTVK---KALAKA------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38754-1", "uniprot_id": "RL14B_YEAST", "id": "P38754-1", "name": "Large ribosomal subunit protein eL14B", "aln": "MSTDSIVKASNWRLVEVGRVVLIKKGQSAGKLAAIVEIIDQKKVLIDGPKAGVPRQAINLGQVVLTPLTFALPRGARTATVSKKWAAAGVCEKWAASSWAKKIAQRERRAALTDFERFQVMVLRKQKRYTVK---KALAKA------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9CR57-1", "uniprot_id": "RL14_MOUSE", "id": "Q9CR57-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MVFRRYVEVGRVAYISFGPHAGKLVAIVDVIDQNRALVDGPCTRVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINTKWAATRWAKKIDARERKAKMTDFDRFKVMKAKKMRNRIIKTEVKKLQRAAILKASPKKAAVAKAAIAAAAAAAAAKAKVPAKKATGPGKKAAGQKAPAQKAAGQKAAPPAKGQKGQKTPAQKAPAPKAAGKKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63507-1", "uniprot_id": "RL14_RAT", "id": "Q63507-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MVFRRFVEVGRVAYISFGPHAGKLVAIVDVIDQNRALVDGPCTRVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINTKWAATRWAKKIDARERKAKMTDFDRFKVMKAKKMRNRIIKTEVKKLQRAALLKASPKKAAVAKAAIAAAAAA---KAKVPAKKATGPGQKAAAQKASAQKAAGQKAAPPAKGQKGQKTPAQKAPAPKAAGKKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50914-1", "uniprot_id": "RL14_HUMAN", "id": "P50914-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MVFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSAHQKYVRQAWQKADINTKWAATRWAKKIEARERKAKMTDFDRFKVMKAKKMRNRIIKNEVKKLQKAALLKASPKKAPGTKGTAAAAAAA--AAAKVPAKKITAASKKAPAQKVPAQKATGQKAAPAPKAQKGQKAPAQKAPAPKASGKKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P55841-1", "uniprot_id": "RL14_DROME", "id": "P55841-1", "name": "Large ribosomal subunit protein eL14", "aln": "--------MPFERFVQTGRIAKASAGPLKGRLVAIVDVIDQNRVLVDGPLTGVPRQEYRLNNLHLTKYRIKFPYTAPTRIVRKAWTESDLKAQWKVSPWSVKAQNICKRSSLNDFDRFKLRYAKRQRNKLLTIAFNTLKKRTKADGTPR-----------------------------VLKKDRRERLRAEKAKGGKKAAAKK----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:.**:. . * *:*.***::***::.*:*** : * ** : : ** : :* * * : * : : :* .: *: * ::: :.**:**:: :: :. :. : * : ", "identical_positions": 34, "similar_positions": 41, "identity": "15.11%" }, { "cls_id": "homologset.agr.RGD:621181", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZM2-1", "uniprot_id": "RL15_MOUSE", "id": "Q9CZM2-1", "name": "Large ribosomal subunit protein eL15", "aln": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61313-1", "uniprot_id": "RL15_HUMAN", "id": "P61313-1", "name": "Large ribosomal subunit protein eL15", "aln": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61314-1", "uniprot_id": "RL15_RAT", "id": "P61314-1", "name": "Large ribosomal subunit protein eL15", "aln": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O17445-1", "uniprot_id": "RL15_DROME", "id": "O17445-1", "name": "Large ribosomal subunit protein eL15", "aln": "MGAYRYMQELYRKKQSDVMRYLLRIRVWQYRQLTKLHRSPRPTRPDKARRLGYRAKQGFVIYRIRVRRGGRKRPVPKGCTYGKPKSHGVNQLKPYRGLQSIAEERVGRRLGGLRVLNSYWIAQDASYKYFEVILIDTHHSAIRRDPKINWICKHVHKHRELRGLTSAGKSSRGIGKGYRYSQTIGGSRRAAWKRKNREHMHRKR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54780-1", "uniprot_id": "RL15B_YEAST", "id": "P54780-1", "name": "Large ribosomal subunit protein eL15B", "aln": "MGAYKYLEELERKKQSDVLRFLQRVRVWEYRQKNVIHRAARPTRPDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPKGATYGKPTNQGVNELKYQRSLRATAEERVGRRAANLRVLNSYWVNQDSTYKYFEVILVDPQHKAIRRDARYNWICNPVHKHREARGLTATGKKSRGINKGHKFNNTKAG-RRKTWKRQNTLSLWRYRK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P05748-1", "uniprot_id": "RL15A_YEAST", "id": "P05748-1", "name": "Large ribosomal subunit protein eL15A", "aln": "MGAYKYLEELQRKKQSDVLRFLQRVRVWEYRQKNVIHRAARPTRPDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPKGATYGKPTNQGVNELKYQRSLRATAEERVGRRAANLRVLNSYWVNQDSTYKYFEVILVDPQHKAIRRDARYNWICDPVHKHREARGLTATGKKSRGINKGHKFNNTKAG-RRKTWKRQNTLSLWRYRK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*::** *******:*:* *:* *:*** . :**:.*************:****:****:*****.********.***** :***:** *.*:: ****.**: . ********: :*::**:*****:*. *.****:. :** . ****** ****::*:.***:.**::: :* .* ** :*:*:* : * * ", "identical_positions": 125, "similar_positions": 51, "identity": "60.98%" }, { "cls_id": "homologset.agr.RGD:621182", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12001-1", "uniprot_id": "RL18_RAT", "id": "P12001-1", "name": "Large ribosomal subunit protein eL18", "aln": "MGVDIRHNKD-RKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTITDDVRILEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALESPKGRGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35980-1", "uniprot_id": "RL18_MOUSE", "id": "P35980-1", "name": "Large ribosomal subunit protein eL18", "aln": "MGVDIRHNKD-RKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTVTDDVRILEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALESPKGRGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07020-1", "uniprot_id": "RL18_HUMAN", "id": "Q07020-1", "name": "Large ribosomal subunit protein eL18", "aln": "MGVDIRHNKD-RKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTITDDVRVQEVPKLKVCALRVTSRARSRILRAGGKILTFDQLALDSPKGCGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VS34-1", "uniprot_id": "RL18_DROME", "id": "Q9VS34-1", "name": "Large ribosomal subunit protein eL18", "aln": "MGIDINHKYD-RKVRRTEPKSQDVYLRLLVKLYRFLQRRTNKKFNRIILKRLFMSKINRPPLSLQRIARFFKAANQPESTIVVVGTVTDDARLLVVPKLTVCALHVTQTARERILKAGGEVLTFDQLALRSPTGKNTLLLQGRRTARTACKHFGKAPGVPHSHTRPYVRSKGRKFERARGRRSSCGYKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX50-1", "uniprot_id": "RL18B_YEAST", "id": "P0CX50-1", "name": "Large ribosomal subunit protein eL18B", "aln": "MGIDHTSKQHKRSGHRTAPKSDNVYLKLLVKLYTFLARRTDAPFNKVVLKALFLSKINRPPVSVSRIARALKQEGAANKTVVVVGTVTDDARIFEFPKTTVAALRFTAGARAKIVKAGGECITLDQLAVRAPKGQNTLILRGPRNSREAVRHFGMG---PHKGKAPRILSTGRKFERARGRRRSKGFKV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX49-1", "uniprot_id": "RL18A_YEAST", "id": "P0CX49-1", "name": "Large ribosomal subunit protein eL18A", "aln": "MGIDHTSKQHKRSGHRTAPKSDNVYLKLLVKLYTFLARRTDAPFNKVVLKALFLSKINRPPVSVSRIARALKQEGAANKTVVVVGTVTDDARIFEFPKTTVAALRFTAGARAKIVKAGGECITLDQLAVRAPKGQNTLILRGPRNSREAVRHFGMG---PHKGKAPRILSTGRKFERARGRRRSKGFKV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* : . *. :*. ***:::**:****** ** ***: **:::** **:*: ****:*:.*: * :* . :.* *****:***.*: .** .*.**:.: ** :*::***: :*:****: :*.* .*::* * *..* . :*** . **. . * : *.*********** * *:* ", "identical_positions": 90, "similar_positions": 55, "identity": "47.62%" }, { "cls_id": "homologset.agr.RGD:621183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84098-1", "uniprot_id": "RL19_HUMAN", "id": "P84098-1", "name": "Large ribosomal subunit protein eL19", "aln": "MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEETKK-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84100-1", "uniprot_id": "RL19_RAT", "id": "P84100-1", "name": "Large ribosomal subunit protein eL19", "aln": "MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEETKK-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84099-1", "uniprot_id": "RL19_MOUSE", "id": "P84099-1", "name": "Large ribosomal subunit protein eL19", "aln": "MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEETKK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P5L3-1", "uniprot_id": "RL19_DANRE", "id": "Q6P5L3-1", "name": "Large ribosomal subunit protein eL19", "aln": "MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLVKDGLIIKKPVTVHSRARCRKNTLARRKGRHMGVGKRKGTANARMPEKLCWMRRMRILRRLLRRYREAKKIDRHMYHSLYLRAKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRTKTREARKRREERQQAKKEEIIKTLSKEDETKK-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36241-1", "uniprot_id": "RL19_DROME", "id": "P36241-1", "name": "Large ribosomal subunit protein eL19", "aln": "MSSLKLQKRLAASVLRCGKKKVWLDPNEINEIANTNSRQNIRKLIKDGLIIKKPVVVHSRYRVRKNTEARRKGRHCGFGKRKGTANARMPTKLLWMQRQRVLRRLLKKYRDSKKIDRHLYHDLYMKCKGNVFKNKRVLMEYIHKKKAEKQRSKMLADQAEARRQKVREARKRREERIATKKQELIALHAKEDEIAAKAATAGH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CX82-1", "uniprot_id": "RL19A_YEAST", "id": "P0CX82-1", "name": "Large ribosomal subunit protein eL19A", "aln": "MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRD----ALLKEDA----------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0CX83-1", "uniprot_id": "RL19B_YEAST", "id": "P0CX83-1", "name": "Large ribosomal subunit protein eL19", "aln": "MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRD----ALLKEDA----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *: *****:**: **:******** .***::***: ****:*:* *::*.*.***: * * :: ::*:*** * ****** :**:* :: *::* *:***** :**:: ***:*:** ** . ***.**:** *:*:* : **: *.* * ::***** * : **.** :* *:: **: ", "identical_positions": 100, "similar_positions": 49, "identity": "49.26%" }, { "cls_id": "homologset.agr.RGD:621185", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35052-1", "uniprot_id": "CDS1_RAT", "id": "O35052-1", "name": "Phosphatidate cytidylyltransferase 1", "aln": "MLELRHRGGCPGPGGAGTPPPREGEAAGGDHETESTSDKETDIDDRYGDLDARGDSDVPEVPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFQEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLIRYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMIWFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVIFGFIAAYVLSKYQYFVCPVEYRSDVNSFVTECEPSELFQLQNYSLPPFLQAVLSRETVSLYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRGP---NPSKVLQQLLVLQPEQQLNIYRTLKIHLTEKGILQPTWKV-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98191-1", "uniprot_id": "CDS1_MOUSE", "id": "P98191-1", "name": "Phosphatidate cytidylyltransferase 1", "aln": "MLELRHRGGCPGPGGAGAPPPREGEAAGGDHETESTSDKETDIDDRYGDLDARGDSDVPEVPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFHEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLIRYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMIWFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVIFGFIAAYVLSKYQYFVCPVEYRSDVNSFVTECEPSELFQLQNYSLPPFLQAVLSRETVSLYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRGP---NPSKVLQQLLVLQPEQQLNIYRTLKIHLTEKGILQPTLKV-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92903-1", "uniprot_id": "CDS1_HUMAN", "id": "Q92903-1", "name": "Phosphatidate cytidylyltransferase 1", "aln": "MLELRHRGSCPGPREAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDLDSRTDSDIPEIPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFHEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLIRYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMIWFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVVFGFIAAYVLSKYQYFVCPVEYRSDVNSFVTECEPSELFQLQTYSLPPFLKAVLRQERVSLYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRGP---NPSKVLQQLLVLQPEQQLNIYKTLKTHLIEKGILQPTLKV-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7N6-1", "uniprot_id": "A0A8M1Q7N6_DANRE", "id": "A0A8M1Q7N6-1", "name": "Phosphatidate cytidylyltransferase", "aln": "MTELRRRG---GGDQDSAENISDKEADG--------DDRLAFPDEGDGEMVGDSKAETPDAPPSTDNTPQCLNKALEGLSSRWKNWWIRGILSLTMIIGFFLIIYLGPIMLIIVVMGVQIKCFHEIITIGYRVYHSYELPWFRTLSWYFLICVNYFFYGETVADYFGALVQREEPLQFLVRYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLIVVTQSHLVIQNLFEGMIWFIVPISIVICNDIMAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVLSFFFAYLLSQYQYFVCPVEYDSETNRFAVECEPSNLFMIQEYTLPAVVQNALRWKTVNLYPFQIHSIALSSFASLIGPFGGFFASGFKRAFKIKDFADTIPGHGGIMDRFDCQYLMATFVHVYITSFIRGP---NPSKVLQQLLVLQPEQQLGIFNTLRNQLREKGLLPPAVEEAQ---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P56079-1", "uniprot_id": "CDS_DROME", "id": "P56079-1", "name": "Phosphatidate cytidylyltransferase, photoreceptor-specific", "aln": "MAEVRRRK---GEDEPLEDTAISGSDAANKRNSAADSSDHVDSEEEKIPEEKFVDELAKNLPQGTDKTPEILDSALKDLPDRWKNWVIRGIFTWIMICGFALIIYGGPLALMITTLLVQVKCFQEIISIGYQVYRIHGLPWFRSLSWYFLLTSNYFFYGENLVDYFGVVINRVEYLKFLVTYHRFLSFALYIIGFVWFVLSLVKKYYIKQFSLFAWTHVSLLIVVTQSYLIIQNIFEGLIWFIVPVSMIVCNDVMAYVFGFFFGRTPLIKLSPKKTWEGFIGGGFATVLFGILFSYVLCNYQYFICPIQYSEEQGRMTMSCVPSYLFTPQEYSLKLFGIG----KTLNLYPFIWHSISLSLFSSIIGPFGGFFASGFKRAFKIKDFGDMIPGHGGIMDRFDCQFLMATFVNVYISSFIRTP---SPAKLLTQIYNLKPDQQYQIYQSLKDNLG--DMLT----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38221-1", "uniprot_id": "CDS1_YEAST", "id": "P38221-1", "name": "Phosphatidate cytidylyltransferase", "aln": "----------------MSDNPEMKPHG--------TSKEIVESVTDATSKAIDKLQEELHKDASESVTPVTKESTAATKESRKYNFFIRTVWTFVMISGFFITLASGHAWCIVLILGCQIATFKECIAVTSASGREKNLPLTKTLNWYLLFTTIYYLDGKSLFKFFQATFYEYPVLNFIVTNHKFICYCLYLMGFVLFVCSLRKGFLKFQFGSLCVTHMVLLLVVFQAHLIIKNVLNGLFWFLLPCGLVIVNDIFAYLCGITFGKTKLIEISPKKTLEGFLGAWFFTALASIILTRILSPYTYLTCPVEDLHTNFFSNLTCELNPVFLPQVYRLPPIFFDKVQINSITVKPIYFHALNLATFASLFAPFGGFFASGLKRTFKVKDFGHSIPGHGGITDRVDCQFIMGSFANLYYETFISEHRITVDTVLSTILMNLNDKQIIELIDILIRFLSKKGIISAKNFEKLADIFNVTKKSLTNHS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . . . ** ..: .* *: ** : : ** * : : * :: : *: *:* *:: : ** ::*.**:*: *:: *:.: .:* . . . *:*:: *:*:.:.**: ** ** ** * . ** :. **: **:.* *::*:*:*:::*::**::* . :: **: **: *: **:* **::***** ***:*. * *.: .:: : :*. * *: **:: * . :* * * * . : :.: *: *:: *: *:*::.*********:**:**:***.. ******* **.***::*.:*.::* :** : : : *: .* : * * .:: ", "identical_positions": 124, "similar_positions": 124, "identity": "25.78%" }, { "cls_id": "homologset.agr.RGD:621186", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99L43-1", "uniprot_id": "CDS2_MOUSE", "id": "Q99L43-1", "name": "Phosphatidate cytidylyltransferase 2", "aln": "MTELRQRVVRED-APPED-KESESEAKLDGETASDS----ESRAETAP-----------LPTSVDDTPEVLNRALSNLSSRWKNWWVRGILTLAMIAFFFIIIYLGPMVLMMIVMCVQIKCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFALYLTGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSGYRCFVCPVEYNNDTNSFTVDCEPSDLFRLQEYNIPGVIQSAIGWKTVRMYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGP---NPSKLIQQFLTLRPDQQLHIFNTLKSHLTDKGILTSALEDE----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91XU8-1", "uniprot_id": "CDS2_RAT", "id": "Q91XU8-1", "name": "Phosphatidate cytidylyltransferase 2", "aln": "MTELRQRAVRED-APPED-KESESEAKLDGETASDS----ESRAETAP-----------PPTSIDDTPEVLNRALSNLSSRWKNWWVRGILTMAMIAFFFIIIYLGPMVLMMIVMCVQIKCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFTLYLTGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSGYRCFVCPVEYNNDTNSFTVDCEPSDLFRLQEYNIPGVIQSLVGWKTMRMYPFQIHS-ALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGP---NPSKLIQQFLTLRPDQQLHIFNTLKSHLTDKGILMSALEEE----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95674-1", "uniprot_id": "CDS2_HUMAN", "id": "O95674-1", "name": "Phosphatidate cytidylyltransferase 2", "aln": "MTELRQRVAHEPVAPPED-KESESEAKVDGETASDS----ESRAESAP-----------LPVSADDTPEVLNRALSNLSSRWKNWWVRGILTLAMIAFFFIIIYLGPMVLMIIVMCVQIKCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFTLYLIGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSGYRCFVCPVEYNNDTNSFTVDCEPSDLFRLQEYNIPGVIQSVIGWKTVRMYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGP---NPSKLIQQFLTLRPDQQLHIFNTLRSHLIDKGMLTSTTEDE----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56079-1", "uniprot_id": "CDS_DROME", "id": "P56079-1", "name": "Phosphatidate cytidylyltransferase, photoreceptor-specific", "aln": "MAEVRRRKGEDE--PLEDTAISGSDAANKRNSAADSSDHVDSEEEKIPEEKFVDELAKNLPQGTDKTPEILDSALKDLPDRWKNWVIRGIFTWIMICGFALIIYGGPLALMITTLLVQVKCFQEIISIGYQVYRIHGLPWFRSLSWYFLLTSNYFFYGENLVDYFGVVINRVEYLKFLVTYHRFLSFALYIIGFVWFVLSLVKKYYIKQFSLFAWTHVSLLIVVTQSYLIIQNIFEGLIWFIVPVSMIVCNDVMAYVFGFFFGRTPLIKLSPKKTWEGFIGGGFATVLFGILFSYVLCNYQYFICPIQYSEEQGRMTMSCVPSYLFTPQEYSLK---LFGIG-KTLNLYPFIWHSISLSLFSSIIGPFGGFFASGFKRAFKIKDFGDMIPGHGGIMDRFDCQFLMATFVNVYISSFIRTP---SPAKLLTQIYNLKPDQQYQIYQSLKDNLGD--MLT----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38221-1", "uniprot_id": "CDS1_YEAST", "id": "P38221-1", "name": "Phosphatidate cytidylyltransferase", "aln": "MSDNPEMKPHGT---SKEIVESVTDATSKAIDKLQEELHKDASESVTP--------------------VTKESTAATKESRKYNFFIRTVWTFVMISGFFITLASGHAWCIVLILGCQIATFKECIAVTSASGREKNLPLTKTLNWYLLFTTIYYLDGKSLFKFFQATFYEYPVLNFIVTNHKFICYCLYLMGFVLFVCSLRKGFLKFQFGSLCVTHMVLLLVVFQAHLIIKNVLNGLFWFLLPCGLVIVNDIFAYLCGITFGKTKLIEISPKKTLEGFLGAWFFTALASIILTRILSPYTYLTCPVEDLHTNFFSNLTCELNPVFLPQVYRLPPIFFDKVQINSITVKPIYFHALNLATFASLFAPFGGFFASGLKRTFKVKDFGHSIPGHGGITDRVDCQFIMGSFANLYYETFISEHRITVDTVLSTILMNLNDKQIIELIDILIRFLSKKGIISAKNFEKLADIFNVTKKSLTNHS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: . . :: * ::* . :. :: . * : : .* *: :* : * **. * : : * :: : *: *:* *:: : .** ::*.**:*: *:: *:.: .:* . . . *.:: . *:*:.: **: ** ** ** * . ** : **: **:** *::*:*:*:::*::**::* . :: **::**: *: **:* **::***** ***:*. * *.: .:::: ::. * : **:: . .: * . :* * * : : ::: : *: *: *: *:*::.*********:**:**:***.. ******* **.***::*.:*.*:* :** : * : .*. .* .: : * * . :: ", "identical_positions": 125, "similar_positions": 138, "identity": "26.04%" }, { "cls_id": "homologset.agr.RGD:621188", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88281-1", "uniprot_id": "MEGF6_RAT", "id": "O88281-1", "name": "Multiple epidermal growth factor-like domains protein 6", "aln": "MPVRAEARAAWR--VVALALLLLPAMPAAS--PPLTP-RPLQPSMPHVCAEQKLTLVGHRQPCVQAFSRIVPVWRRTGCAQQAWCIGQERRTVYYMSYRQVYATEARTVFRCCPGWSQKPGQEGCLSDV-----------------------------------DECASANGGCEGPCCNTVGGFYCRCPPGYQLQGDGKTCQDVDECRAHNGGCQHRCVNTPGSYLCECKPGFRLHTDGRTCLAISSCTLGNGGCQHQCVQLTVTQHRCQCRPQYQLQEDGRRCVRRSPCAEGNGGCMHICQELRGLAHCGCHPGYQLAADRKTCEDVDECALGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAGNGGCSHGCSHTSTGPLCTCPRGYELDEDQKTCIDIDDCAN-SPCCQQACANTPGGYECSCFAGYRLNTDGCGCEDVDECASGHGGCEHHCSNLAGSFQCFCEAGYRLDEDRRGCTSLEESVVDLDGRLPFVR--PLPHIAVLRDELPRLFQDDYGAEEEAAAAELRGEHTLTEKFVCLDHSFGHDCSLTCDDCRNGGTCFPGQDGCDCPEGWTGIICNETCPPDTFGKNCSSPCTCQNGGTCDPVLGACRCPPGVSGAHCEDGCPKGFYGKHCRKKCHCANRGRCHRLYGACLCDPGLYGRFCHLACPPWAFGPGCSEDCLCEQSHTRSCNPKDGSCSCKAGFQGERCQAECESGFFGPGCRHRCTCQPGVACDPVSGECRTQCPPGYQGEDCGQECPVGTFGVNCSGSCSCVGAPCHRVTGECLCPPGKTGEDCGADCPEGRWGLGCQEICPACEHGASCNPETGTCLCLPGFVGSRCQDTCSAGWYGTGCQIRCACANDGHCDPTTGRCSCAPGWTGLSCQRACDSGHWGPDCIHPCNCSAGHGNCDAVSGLCLCEAGYEGPRCEQSCRQGYYGPSCEQKCRCEHGAACDHVSGACTCPAGWRGSFCEHACPAGFFGLDCDSACNCSAGAPCDAVTGSCICPAGRWGPRCAQSCPPLTFGLNCSQICTCFNGASCDSVTGQCHCAPGWMGPTCLQACPPGLYGKNCQHSCLCRNGGRCDPILGQCTCPEGWTGLACENECLPGHYAAGCQLNCSCLHGGICDRLTGHCLCPAGWTGDKCQSSCVSGTFGVHCEEHCACRKGASCHHVTGACFCPPGWRGPHCEQACPRGWFGEACAQRCLCPTNASCHHVTGECRCPPGFTGLSCEQACQPGTFGKDCEHLCQCPGETWACDPASGVCTCAAGYHGTGCLQRCPSGRYGPGCEHICKCLNGGTCDPATGACYCPAGFLGADCSLACPQGRFGPSCAHVCACRQGAACDPVSGACICSPGKTGVRCEHGCPQDRFGKGCELKCACRNGGLCHATNGSCSCPLGWMGPHCEHACPAGRYGAACLLECFCQNNGSCEPTTGACLCGPGFYGQACEHSCPSGFHGPGCQRVCECQQGAPCDPVSGQCLCPAGFHGQFCEKGCESGSFGDGCLQQCNCHTGVPCDPISGLCLCPPGRTGAACDLDCRRGRFGPGCALRCDCGGGADCDPISGQCHCVDSYMGPTCR--------EVPTQISSSR---PAPQHPSSR---AMKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80V70-1", "uniprot_id": "MEGF6_MOUSE", "id": "Q80V70-1", "name": "Multiple epidermal growth factor-like domains protein 6", "aln": "MPVGVEARASWR--VVALTLLLLPAVPAAS--QPLPP-RPLQPSMPHVCAEQKLTLVGHRQPCVQAFSRVVPVWR-SGCGQQAWCVGQERRTVYYMSYRQVYATEARTVFRCCPGWSQKPGQEGCLSDV-----------------------------------DECANANGGCEGPCCNTVGGFYCRCPPGYQLQGDGKTCQDVDECRSHNGGCQHRCVNTPGSYLCECKPGFRLHTDGRTCLAISSCTLGNGGCQHQCVQLTVTQHRCQCRPQYQLQEDGRRCVRRSPCADGNGGCMHTCQELRGLAHCGCHPGYQLAADRKACEDVDECALGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAGNGGCSHGCSHTSTGPLCTCPRGYELDEDQKTCIDIDDCAN-SPCCQQVCANTPGGYECSCFAGYRLNTDGCGCEDVDECASGHSGCEHHCSNLAGSFQCFCEAGYRLDEDRRGCTPLEESVVDLDGQLPFVR--PLPHIAVLGDELPQLFQDDYGAEEEAVA-ELRGEHTLTEKFVCLDHSFGHDCSLTCDDCRNGGTCFPGLDGCDCPEGWTGIICNETCPPDTFGKNCSSPCICQNGGTCDPVSGACRCPPGVSGAHCEDGCPKGFYGKHCRKKCHCANRGRCHRLYGACLCDPGLYGRFCHLACPPWAFGPGCSEDCLCEQSHTRSCNSKDGSCSCKAGFQGERCEAECEPGSFGPGCRNRCTCRPGVACDPVSGECRTQCPPGYQGEDCGQECPVGTFGVNCSGSCSCVGAPCHRVTGECLCPPGKTGEDCGADCPEGRWGLGCQEICPACEHGASCDPETGTCLCLPGFVGSRCQDACPAGWFGTGCQMRCACANDGHCHPATGRCSCAPGWTGLSCQRACDSGHWGPDCIHPCNCSAGHGNCDAVSGLCLCEAGYEGPQCEQWCRQGYFGPGCEQKCRCEHGATCDHVSGACTCPAGWRGSFCEHACPAGFFGLDCGSACNCSAGAPCDAVTGSCICPAGRWGPHCAQTCPPLTFGLNCSQICTCFNGASCDPVLGQCHCAPGWMGPTCLQACPAGLYGKNCQHSCLCRNGGSCDPILGQCTCPEGWTGLACENECLPGHHGAGCRLNCSCLNGGTCDRLTGHCRCPAGWTGDKCQSPCVSGMFGVHCEEHCACRKGATCHHVTGACLCPPGWRGSHCEQACPRGWFGEACAQRCHCPPGASCHHVSGECHCPPGFTGPGCEQACQPGTFGKDCEHPCQCPGETWACHPASGACVCAAGYHGTDCQQRCPSGRYGPGCEQICKCLNGGTCDPATGACYCPAGFLGADCSLACPQGRFGPSCAHVCTCGQGAACDPVSGTCICPPGKTGGHCERGCPQDRFGKGCEHKCACRNGGLCHATNGSCSCPLGWMGPHCEHACPAGRYGAACLLECSCQNNGSCEPTSGACLCGPGFYGQACEDTCPAGFHGSGCQRVCECQQGAPCDPVSGRCLCPAGFRGQFCERGCKPGFFGDGCLQQCNSPTGVPCDPISGLCLCPPGRAGTTCDLDCRRGRFGPGCALRCDCGGGADCDPISGQCHCVDSYTGPTCR--------EVPTQLSSIR---PAPQHSSSK---AMKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75095-1", "uniprot_id": "MEGF6_HUMAN", "id": "O75095-1", "name": "Multiple epidermal growth factor-like domains protein 6", "aln": "MSFLEEARAAGRAVVLALVLLLLPAVPVGASVPPRPL-LPLQPGMPHVCAEQELTLVGRRQPCVQALSHTVPVWK-AGCGWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLS-------------------------------------AECS-ASLCFHGGRCVPGSAQPCHCPPGFQGP---RCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD-SPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVR--PLPHIAVLQDELPQLFQDDDVGADEEEA-ELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLR-------------------------------------------GWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TH19-1", "uniprot_id": "A0AB32TH19_DANRE", "id": "A0AB32TH19-1", "name": "", "aln": "---------------MDLHVLLLLLFLLTKIRPSCCL-RALHPFMPNVCSEPERVIRAEKQPCVQAFIQMVKVWR-QGCTGHAWCMDFERRTTYYIGYKQVYRQDFKMAYKCCPGWSQNNSKMGCLY----------------------------------------------------------------------------HIDECQVHNGGCQHRCVNTRGSYYCECNPGFRLHVDGRTCIAVLSCSVNNGGCEHECVQLSPVHFQCRCRRGYQLTADGKRCRLRNPCVEKNGGCVHLCRSDGGRVVCSCHQGFMLAVDQKSCEDVNECETGLAACAHSCRNTPGSFSCICNPGYELGSDGRKCYRIEMEIVNTCDSDNGGCSHRCQHGVLGPVCSCNHGYQLAEDLKTCLDLEECEEGTSCCEQDCTNYPGGYECYCRAGYRLNADGCGCDDVDECASDRGGCEHTCQNTAGSYHCFCRFGYRLGEDRHSCISLQRSVEELPGPVVVER--PLLHLALLQDYPQPLER--YHDYEEDSFGELRAESTFAEKFVCLNGTFGHDCSLTCDDCSNGGYCNAEGDACDCPDGWTGILCNQTCPEGTFGKNCSFTCKCRNGGTCDPISGKCRCPPGVNGDLCQDGCPKGMYGKHCNKKCNCANNGRCHRTYGACLCDPGLYGRFCHLPCPKWSYGSGCSSECQCVQQNTLECHRRHGTCVCKPGYQGKTCNRECDSGFYGPGCRLKCQCPAGVSCHPMSGQCQRQCPAGLHGEHCDRECPMGQFGVGCTQFCDCKGAPCNSVTGKCHCPAGQTGQHCEKECEEGRWGLGCAESCPSCDNGGVCDRQNGTCVCSPGFMGNLCQNVCPDGHFGLSCLLRCSCQNEGKCHHVTGLCVCKDGWMGPNCAKACVAGRWGPNCANQCDCRSSVGSCDPVIGLCHCEAGYMGPRCDQKCPQGFFGQSCQHRCQCENGAVCEHVSGACTCLAGWTGTYCEKPCPEGFHGLECQQKCQCLNGGRCHPVTGGCQCPSGWVGPVCNATCEAGTFGPACSQTCRCHNNGTCDPADGRCECGAGWTGSSCEQECSAGLYGVGCNQHCLCQNGGSCDRISGHCTCVSGWTGVACELECAAGHFGMDCQHKCECVNGGVCDRHSGRCLCPAGWTGTHCETACTQGFYGPGCKERCRCDHNAACHHITGTCLCPAGWRGTHCEKVCLPGSYGKRCAHRCQCPHGTSCNHVTGQCGCPAGLTGSGCERMCQSGTFGVNCNQVCQCSELNQLCHPVTGVCYCAPGYYGSKCETECEAGRYGPNCEQECQCLNNGVCKSSTGTCSCPPGFIGPNCNITCPLGRYGQDCAGVSLCGEGARSDPLTGRCVCRAGQRGRDCGKGCAEGWFGENCDQRCNCSNGGVCDALTGHCSCTLGWTGDTCEEVCPRGRYGSDCSEVCDCKNNSTCDRVTGVCLCSPGFYGHLCQHACPVGFHGHRCQLLCDCGANAPCDPETGRCLCPAGYQGLRCERECELGTFGADCVHRCDCDGDTPCDPINGRCLCAPGKTGSRCDIGCGVNRFGPDCSQRCECLNGGQCDPRNGRCTCLNGWIGPSCQQA------EWPSLNVRRCTHWMTLVYKALLALVPS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B4A3-1", "uniprot_id": "A0A8M3B4A3_DANRE", "id": "A0A8M3B4A3-1", "name": "", "aln": "--------------MKNVDLLLSLIILVDGINAVSRLGKDLKPHMPNVCAEKEVKLVAQMQPCVQAFTRMVKAWK-QGCQGQSWCVGYERRTAYYTAYRQVYRQEQQTVYKCCPGWSQLNGEAGCLYPVCRSGVCFNGGQCKEGSAQLCVCPAGFSGPSCQYDVNECEETNGGCEALCCNTIGSFYCKCPAGQELKEDGKTCQDIDECQVHNGGCQHTCVNTRGSYHCQCNAGSRLHVDGRTCIAVQSCGVGNGGCEHFCVQQTAGHVQCRCRPDYRLDADGKHCTLVNPCAEQNGGCSQMCHRDGAQARCECHPGYQLAEDGKTCEDIDECALGQTDCAHGCRNTRGSFMCVCSAAYELGVDGKQCYRIEMEIVNSCDHDNGGCSHHCEHSTAGPLCSCNEGYQLDHDHKTCVDINECVDGSSCCEHDCTNYPGGYECYCTAGYRLNTDGCSCDDIDECLAVNGGCDHACLNSAGSFQCSCRRGYRLDEDRRSCILMEESVEALSSGQTVNKPGPGPQLTILQDFDQILEK--YEDYEDD-TGELRAESTLAEKFICLNDSFGVDCSLSCEDCVNGGVCNKHRNACDCPDGWTGVVCNETCPEGWFGRNCSLLCKCKNGGVCDPVSGSCRCPPGVSGELCQDGCPKGLYGKFCNKRCNCANNGRCHRTYGACLCDPGLYGRFCHLPCPKWMFGPGCSEECQCVQQNTIECHRHHGDCICKPGYRGHTCKDECESGFFGSACENKCSCPPGVTCDHVTGACQPKCPAGKTGDKCDQDCVEGRFGIGCSQSCDCSGAPCDKVTGQCTCPAGTFGKRCEKECPEGRWGLGCQEWCPVCENGGRCDRRNGTCVCSPGFIGRLCQNSCPAGRFGVGCQLRCVCDLGVRCNPVSGRCSCPPGWTGHNCRKVCDAGRWGLDCESVCDCRNADGVCDAQTGRCHCEAGFTGARCDQKCPAGSFGPGCKHRCQCENQASCDHVGGACTCKTGWTGTFCEKPCPQGFYGLDCQQKCVCLNGGLCDHVSGQCFCKAGWIGTRCNQTCPAGWFGVSCSQTCVCHNNSSCDAVSGQCECGAGWTGDTCSQRCPAGVFGDGCVHRCLCQNGASCDPESGHCFCPSGWTGAACQLECPAGRFGSDCQDRCECVNGAQCDGQTGRCVCPPGWTGERCENECERGWFGVGCEDRCQCDHGAVCHHVSGQCLCPAGWRGRRCEKACLPGSFGQDCVQRCSCPSGSSCHHVTGHCGCAPGFTGDGCEHSCLPGTFGQDCNQVCQCSERNQLCHPVTGVCYCAPGFTGLKCEQTCPQGLYGSGCEHQCECLNGGVCLSDSGSCQCPAGFIGAQCNQTCPAGRYGLDCAHVSACGTGVRNDPATGRCTAHQ---------VCPPGWFGSGCSQRCDCSNRGVCDGVSGNCSCALGWTGKHCDKECPDGSFGPDCSLQCSCQNNSTCDRVTGSCHCRPGYYGHLCEHACPAGLFGSGCQQQCDCMNGASCHPDTGQCVCPAGVHGPRCQHVCAQGRFGVNCSQSCDCADGASCDPVSGRCVCPSGKTGVRCDSDCSVNRFGPDCSLLCECENGAQCDSRNGRCFCLSGWIGFTCSQS------APPELNSRRSE-------EDQLQLNTS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :** . *:* **:**:* : : .. ******: : * .*: ** ::**:. ****.** .*:*** : : . :** ** * .: *** .:***: ******* **** *** *:*:.* ***.*.***:*: ** :.****:* *** : : :*:** ::* **::* .**.: **.* : *: . . * ** *: ** * *:***::** * : ***.* ** *** *:* ..**** **::**********:*: .****** *.* **:*:* .**:* * :**:*:::* : :.**:: *:* ****** * *****.:***.*:*:*** : ..**:* * * ***::* *. **** ***:.* ::..: * . . : * ::::* * * : :: ***.* *::***:**: :** ****:*:** *** * :.****:****::**:*** . **:*** * *:***.**.: * *******.* *:****** ***.*.*:*:***.***** *****************.** * :*.***.:* * * :* .*. :.* * **.*::*. *: **: * :*..* * * **:*. ::* * :**.* *:.*.::* * **:.*: *.* ****. ***:* **.* *: * :* ******** * ** *::.. *: ..*:*:* ***:* **: *. * :* .* ** * :*. .:* * * ** * .* :.* :*:** :* *:* . * **. * * ****: *.:*:* * * :* .*:::*:*:: * *:**.***** :** *::**:.** **.**:* . * * *. *. *.* * * :* *. * :* . :* *** * *.*..:**.. *:*.*..** * :* * *..*::* .* : ***:**. ** *:* * .**:* **: ** . .*: *::*. ** :*:* **.**** :*:. * * :*: *.:** ** .::*:**:* * *..*:** .**: * .*:** :* : ***. . *.*.:*.* **.*: * * * * **..**: * ***.* * . :*:* **.**:*.:*. :** **:* .*: *. * *. ** :* * . *. . ** .*. * * * *:*.. .* *** *** * *: ** * :*. * * *:**.:*: .:* * * **:**: *:..** *:.* ** * * .*.*.* :*:*:**** :* *:: * * ** .* : *:. ...***:.* *:*..*::* *: .* .:***.*: *:* .*.:**. .*:* *:..: * :* * . ", "identical_positions": 653, "similar_positions": 385, "identity": "40.04%" }, { "cls_id": "homologset.agr.RGD:621189", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35268-1", "uniprot_id": "RL22_HUMAN", "id": "P35268-1", "name": "Large ribosomal subunit protein eL22", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MAP---VKK--LVVKGGKKKKQVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERSKSKITVTSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQDE-EEEEDED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P67984-1", "uniprot_id": "RL22_MOUSE", "id": "P67984-1", "name": "Large ribosomal subunit protein eL22", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MAP---VKK--LVAKGGKKKKQVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERSKSKITVTSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQDE-EEEEDED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47198-1", "uniprot_id": "RL22_RAT", "id": "P47198-1", "name": "Large ribosomal subunit protein eL22", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MAP---VKK--LVAKGGKKKKQVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERSKSKITVTSEEPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQDE-EEEEDED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50887-1", "uniprot_id": "RL22_DROME", "id": "P50887-1", "name": "Large ribosomal subunit protein eL22", "aln": "MAPTAKTNKGDTKTAAAKPAEKKAAPAAAAAKGKVEKPKAEAAKPAAAAAKNVKKASEAAKDVKAAAAAAKPAAAKPAAAKPAAASKDAGKKAPAAAAPKKDAKAAAAPAPAKAAPAKKAASTPAAAPPAKKAAPAKAAAPAAAAPAPAAAAPAVAKPAPKPKAKAAPAPSKVVKKNVLRGKGQKKKKVSLRFTIDCTNIAEDSIMDVADFEKYIKARLKVNGKVNNLG-NNVTFERSKLKLIVSSDVHFSKAYLKYLTKKYLKKNSLRDWIRVVANEKDSYELRYFRISSND-DEDDDAE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P56628-1", "uniprot_id": "RL22B_YEAST", "id": "P56628-1", "name": "Large ribosomal subunit protein eL22B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MAP-----------NTSRKQKVIKTLTVDVSSPTENGVFDPASYSKYLIDHIKVDGAVGNLG-NAIEVTEDGSIVTVVSSAKFSGKYLKYLTKKYLKKNQLRDWIRFVSIRQNQYKLVFYQVTPEDADEEEDDE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P05749-1", "uniprot_id": "RL22A_YEAST", "id": "P05749-1", "name": "Large ribosomal subunit protein eL22A", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MAP-----------NTSRKQKIAKTFTVDVSSPTENGVFDPASYAKYLIDHIKVEGAVGNLG-NAVTVTEDGTVVTVVSTAKFSGKYLKYLTKKYLKKNQLRDWIRFVSTKTNEYRLAFYQVTPEE-DEEEDEE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : :*:* :*:* : .*:.::* *.: ::: ::**:* ..*** . : . .. : * * ** *************.****:*.*: :.*.* ::::. :: :*::* :", "identical_positions": 42, "similar_positions": 45, "identity": "13.95%" }, { "cls_id": "homologset.agr.RGD:621190", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYP0-1", "uniprot_id": "MEGF8_RAT", "id": "Q9QYP0-1", "name": "Multiple epidermal growth factor-like domains protein 8", "aln": "MALGGALAAALALAFAVLGPLSHKVLAGDCKGQRQVLREAPGFVTDGAG--NYSVNGNCEWLIEAPSPQHRILLDFLFLDTECTYDYLFVYDGDSPQGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPGGCQNHGQCKSP-GVCVCEPGWGGPDCGLQECSAYCGS--HGTCASTLGPCRCEPGFLGRACDLHLWENQGAGWWHSVSAGDPAFSARVGAAGAFLSPPGLLAVFGGQDLNKALGDLVLYNFSTNTWESWD-------------------------------------------------------------------------------------------LTPAPAARHSHVAVAWAGFLVLMGGELANGLLTNDVWAFSPLG-GGHWELLAPPASSSSGPPGLAGHAAALVDDIWLYVSGGRTQHDLFSSGLFRFRLDHTSRGYWEQVIPAGGR--PPAATGHSMVFHAPSRTLLVHGGHRPSTARFSVRVNSTELFHVDRRVWTTLKGR----DGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKCYEDGIFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDLMAYKVPPFVFQAPALDYHLDYCSMYTDHSVCSRDPECSWCQG--ACQSAPPPGTPSGACPAASCLGLGRLLSDCQACLAFS------------SPTAPPRGPGTLGWCVHNESCLPRPEQARCRGEQISGTVGWWGPAPVFVTSLEACVTQSFLPGLHLLTFQQPPNASQPDKVSIVRSTTITLTPSAETDVSLVYRG--FIYPMLPGGPGGPGAEDVAVWARAQRLHVLARMARGPDTENMEEVG-RWVAQQEKETRRLQRPGSSRLFPLPGRGNKYAVEIRGQLNGSAGPGHSELTLLWDRTGVPGGSEISFFFLEPYRSLACSSYSSCLGCLADQGCGWCLNSATCHLRQ--GRAHCEDDGNG---ESLLVLVPALCPLCEEHRDCHACTQDPFCEWHQSTNRKGDAACSRRGRGRGALKNPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHS------------------EPRCRSCHGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGP--LGGGNCSLWVGEGLG---LPVALP------------------------ARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGITHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCNFHSHCRRRGPGYCDECQDWTWGEHCERCRPGSFGNATGSG-GCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQICSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRFGGLLPPGGGTARAGPG-LSYCVWVVSATEALQPCAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSS--SWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAGICNQSLGVCICAEG-FGGPDCATKLDGGQLVWETLMDSRLS---ADTASRFLHRLGHTMVEGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAED-GGPGPSPRSFHAAAYVP----------AGRGAMYLLGGLTAG-GITCDFWVLNLTTLQWRQEKAPQSI--------ELPAVAGHTLTAR---RGLSLLLVGGYSPENGFNQQLLEYQLAT-TWVSGAQSGTPPTGLYGHSAVYHEATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAK--------------------------------------------------------PRPRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNTWLLPDLTRPAFVGSPMEESVAHAVAAVGS-RLYISGGFGG-VALGRLLALTLPPDPCRLLPSPEACNQS-GACTWCHGACLSGDQAHRLGCGV--PPCSPMP---------RSPEECRRLRTCSECLARHPRTLQPGDGEASVPRCKWCTNCPEG-ACIGRNGSCTSENDCRINQREVFWAGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLASKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGCGRLLRG--PESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGHCMEGGLSG-----------------PRDGLTCGRPGASWAFLSCPPEDECANGHHDCN-ETQNCHDQPHGYECSCKTGYTMDNVTGVCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSALGGGTCRPCHAFCRGNSHVCVSRKELEMARREPEKYSLDPEEIEAWVAEGPSEDEAVCVNCQNNSYGDRCESCLHGYFLLDG----KCTKCQCNGHADTCNEQDGTGCPCQNNTETGVCQGSS--PSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNCFHEPKRRALGPGRTVLFGVQPKFTNVDIRLTLDVTFGAVDLYVSTSYDTFVVRVAPDTGVHTVHIQPPPPPP---------PPPPPADG--------VPRVASDLGGLGTGSGSGSPV-----------------EPRVREVWPRGLITYVTVTEPSAVLVVRSVRDRLVITYPHEHHALKSSRFYLLLLGVGDPNGPGANGSADSQGLLFFRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFAKVTVCFPPD--------PAGPAPAWKPAGLPP----------------------PAFRRSEPFLAPLLLTGAG-GPWGPMGGGCCPPALPATTAG------------------------------------LRAGPITLEPTEDGMAGVATLLLQLPGGPHAPNGACLGSALVTLRHRLHEYCGGSGGAGGSGHGGGGGRKGLLSQDNLTSMSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60882-1", "uniprot_id": "MEGF8_MOUSE", "id": "P60882-1", "name": "Multiple epidermal growth factor-like domains protein 8", "aln": "MALGGALALALALALAVLGPLSLRVLAGDCKGQRQVLREAPGFVTDGAG--NYSVNGNCEWLIEAPSPQHRILLDFLFLDTECTYDYLFVYDGDSPQGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPGGCQNHGQCKSP-GVCVCEPGWGGPDCGLQECSAYCGS--HGTCASTLGPCRCEPGFLGRACDLHLWENQGAGWWHSVSAGDPAFSARIGAAGAFLSPPGLLAVFGGQDLNKALGDLVLYNFSTNTWESWD-------------------------------------------------------------------------------------------LTPAPAARHSHVAVAWAGLLVLMGGELANGLLTNDVWAFSPLG-GGHWELLAPPASSSSGPPGLAGHAAALVDDIWLYVSGGRTQHDLFSSGLFRFRLDHTSRGYWEQVIPAGGR--PPAATGHSMVFHAPSRTLLVHGGHRPSTARFSVRVNSTELFHVERRVWTTLKGR----DGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKCYEDGIFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDLMAYKVPPFVFQAPALDYHLDYCSMYTDHSVCSRDPECSWCQG--ACQAAPPPGTPSGACPAASCLGLGRLLSDCQACLAFS------------SPTAPPRGPGALGWCVHNESCLPRPEQARCRGEQISGTVGWWGPAPVFVTSLEACVTQSFLPGLHLLTFQQPPNASQPDKVSIVRSTTITLTPSPETDVSLVYRG--FIHPLLPGGPGGPGAEDVAVWARAQRLHVLARMARGPDTENMEEVG-RWVAQQEKETRRLQRPGSDRLFPLPGRGNKYAVEIRGQLNGSAGPGHSELTLLWDRTGVPGGSEISFFFLEPYRSSACTSYSSCLGCLADQGCGWCLNSATCHLRQ--GRAHCEDDGSG---ESLLVLVPALCPLCEEHRDCHACTQDPFCEWHQSTNRKGDAACSRRGRGRGALKNPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHS------------------EPRCRSCGGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGP--LGGGNCSLWVGEGLG---LPVALP------------------------ARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGITHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRRRGPGYCDECQDWTWGEHCERCRPGSFGNATGSG-GCRPCQCNGHGDPRRGHCDNLTGLCFCQDHTEGAHCQICSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRFGGLLPPGGGAARAGPG-LSYCVWVVSATEALQPCVPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSS--SWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAGICNQSLGVCICAEG-FGGPDCATKLDGGQLVWETLMDSRLS---ADTASRFLHRLGHTMVEGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAED-GGPGPSPRSFHAAAYVP----------AGRGAMYLLGGLTAG-GVTRDFWVLNLTTLQWRQEKPPQNM--------ELPAVAGHTLTAR---RGLSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPTGLYGHSAVYHEATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAK--------------------------------------------------------PRPRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNTWLLPALTRPAFVGSPMEESVAHAVAAVGS-RLYISGGFGG-VALGRLLALTLPPDPCRLLPSPEACNQS-GACTWCHGACLSGDQAHRLGCGV--PPCSPMP---------RSPEECRRLRTCSECLARHPRTLQPGDGEASIPRCKWCTNCPEG-ACIGRNGSCTSENDCRINQREVFWAGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLASKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGCGRLLRG--PESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGHCMEGGLSG-----------------PRDGLTCGRPGASWAFLSCPPEDECANGHHDCN-ETQNCHDQPHGYECSCKTGYTMDNVTGVCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGAQDHCLLCRNHTKGSHCEQCLPLFVGSALGGGTCRPCHAFCRGNSHVCVSRKELEMARKEPEKYSLDPEEIETWVAEGPSEDEAVCVNCQNNSYGDRCESCLHGYFLLDG----KCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSS--PSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNCFHEPKRRALGPGRTVLFGVQPKFTNVDIRLTLDVTFGAVDLYVSTSYDTFVVRVAPDTGVHTVHIQPPPPPP---------PPPPPADG--------VPRVAADLGGLGTGSGSGSPV-----------------EPRVREVWPRGLITYVTVTEPSAVLVVRSVRDRLVITYPHEHHALKSSRFYLLLLGVGDPNGPGANGSADSQGLLFFRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFAKVTVCFPPD--------PAGPAPAWKPAGLPP----------------------PAFRRSEPFLAPLLLTGAG-GPWGPMGGGCCPPALPATTAG------------------------------------LRAGPITLEPTEDGMAGVATLLLQLPGGPHAPNGACLGSALVTLRHRLHEYCGGSGGAGGSGHGGGGGRKGLLSQDNLTSMSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7M0-1", "uniprot_id": "MEGF8_HUMAN", "id": "Q7Z7M0-1", "name": "Multiple epidermal growth factor-like domains protein 8", "aln": "MALGKVLAMALVLALAVLGSLSPGARAGDCKGQRQVLREAPGFVTDGAG--NYSVNGNCEWLIEAPSPQHRILLDFLFLDTECTYDYLFVYDGDSPRGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPGGCQSHGQCQPP-GVCACEPGWGGPDCGLQECSAYCGS--HGTCASPLGPCRCEPGFLGRACDLHLWENQGAGWWHNVSARDPAFSARIGAAGAFLSPPGLLAVFGGQDLNNALGDLVLYNFSANTWESWD-------------------------------------------------------------------------------------------LSPAPAARHSHVAVAWAGSLVLMGGELADGSLTNDVWAFSPLG-RGHWELLAPPASSSSGPPGLAGHAAALVDDVWLYVSGGRTPHDLFSSGLFRFRLDSTSGGYWEQVIPAGGR--PPAATGHSMVFHAPSRALLVHGGHRPSTARFSVRVNSTELFHVDRHVWTTLKGR----DGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKCYEDGIFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDLMAYKVPPFVFQAPAPDYHLDYCSMYTDHSVCSRDPECSWCQG--ACQAAPPPGTPLGACPAASCLGLGRLLGDCQACLAFS------------SPTAPPRGPGTLGWCVHNESCLPRPEQARCRGEQISGTVGWWGPAPVFVTSLEACVTQSFLPGLHLLTFQQPPNTSQPDKVSIVRSTTITLTPSAETDVSLVYRG--FIYPMLPGGPGGPGAEDVAVWTRAQRLHVLARMARGPDTENMEEVG-RWVAHQEKETRRLQRPGSARLFPLPGRDHKYAVEIQGQLNGSAGPGHSELTLLWDRTGVPGGSEISFFFLEPYRSSSCTSYSSCLGCLADQGCGWCLTSATCHLRQ--GGAHCGDDGAG---GSLLVLVPTLCPLCEEHRDCHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHS------------------EPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGP--LGGGNCSLWVGEGLG---LPVALP------------------------ARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSR-GCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAARAGPG-LSYCVWVVSATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSS--SWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAGTCNQSLGVCICAEG-FGGPDCATKLDGGQLVWETLMDSRLS---ADTASRFLHRLGHTMVDGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAED-GGPGPSPRSFHAAAYVP----------AGRGAMYLLGGLTAG-GVTRDFWVLNLTTLQWRQEKAPQTV--------ELPAVAGHTLTAR---RGLSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPTGLYGHSAVYHEATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAKRDRMRNVRGSSRGLGQVPGEQPGSWGFREVRKKMALWAALAGTGGFLEEISPHLKEPRPRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNAWLLPDLTRSASVGPPMEESVAHAVAAVGS-RLYISGGFGG-VALGRLLALTLPPDPCRLLSSPEACNQS-GACTWCHGACLSGDQAHRLGCGG--SPCSPMP---------RSPEECRRLRTCSECLARHPRTLQPGDGEASTPRCKWCTNCPEG-ACIGRNGSCTSENDCRINQREVFWAGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGCGRLLRG--PESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSG-----------------PRDGLTCGRPGASWAFLSCPPEDECANGHHDCN-ETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDG----KCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSS--PSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNCFHEPKRRALGPGRTVLFGVQPKFTNVDIRLTLDVTFGAVDLYVSTSYDTFVVRVAPDTGVHTVHIQPPPAPP---------PPPPPADG--------GPRGAGDPGGAGASSGPGAPA-----------------EPRVREVWPRGLITYVTVTEPSAVLVVRGVRDRLVITYPHEHHALKSSRFYLLLLGVGDPSGPGANGSADSQGLLFFRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFAKVTVCFPPD--------PTAPASAWKPAGLPP----------------------PAFRRSEPFLAPLLLTGAG-GPWGPMGGGCCPPAIPATTAG------------------------------------LRAGPITLEPTEDGMAGVATLLLQLPGGPHAPNGACLGSALVTLRHRLHEYCGGGGGAGGSGHGTGAGRKGLLSQDNLTSMSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QBZ9-1", "uniprot_id": "F1QBZ9_DANRE", "id": "F1QBZ9-1", "name": "", "aln": "-----MTFHIQTLLLPVLVVLVPAVWAGDCKGQRQVLRAVPGYVTDGPG--NYSVNGNCEWLIMAPSRNHRIVLNFMFIDTECTYDYLFVYDGDSYQSPLLASLSGKTLPQPIEAKSGKMLLHLFSDANYNLLGFNATYTFSVCPGDCSGHGRCDVATARCQCQQGWGGLDCNTPLCSQACTQRGHGICDKRGLKCICSSGFVGQDCQLGLRDNSGAGQWWEVSSGDVKAAPRTSSAGVYLASTGAMYMFGGFDLNRALEDLVVYNFSTNSWEQMT-------------------------------------------------------------------------------------------FSHSPAPRHSHTAVEWQGSMVIYGGELANHSLASDVWIYRPQ--QNEWQQLG--LSDAPGAPRLANHAAAIVD-HYLYVFGGRTEEDMFSSSLYRFRLRN---GVWEAVQPTGGK--PPATAGHSMIYHSPSKTLLVYGGHRPTTARFSVRVNSTDAFHVEKRFWTSFRSR----FPANGPRERAFHSATVIGNYMVVYGGNVHIHYTEEKCYDEEIFFYHLGCHQWVSVGDSLGQ-----RGVSVRGRYSHVAAVMEGRVLLVAGGYSGIARGDLVAYKVPLFVSSDPGD--RDSVCAEAPSESLCLKNPECSWCEG--RCREYQP----TDPCGSTGCLGLARFLSDCQSCLVFSG-----------VPNSLPRVSGEFGWCVQNESCLPVSEHSACRVDQISGAYGWWGERTRFLTSLPFCRTENYVPGLHLLTFQHPRNQSQPDKVSILRSTSIILNPSTEMDVTLQFRG--FIHPLWSSPP---HQETVAMWARIQKLHFTAQMAAGPNSLQLTDVLGRWSAQEEKDIHKLSRSDGSRLFQNLTRGNWYLIQAEGYLNNSASGQTSEMALTWNRTGLPGGSEISFLFLEPFRSNSCSEYRSCLACLSDQSCGWCPTVNLCFLRSDINQQPCIDPQGE---ERHLLLNPLHCTLCEEYRDCAACTQDPYCEWQINSSKKGDYLCSRRGRLEGSIREPGGCPNVCNQRLTCGECLSNSSQCAWCESAQSCFYFAAYLTKFPYGECRDWYDSVHS------------------VPQCKQCTALTTCSECLQTFQCGWCGDYSNPTIGRCLRGDWGGMNDHSAVNCSTAVAEVKATSPEPQTLSPPRLMELEMDLEMEQLEGMEGDGDAVWSYPSCPDVEECRLGLHTCHPSATCVNTPTSYECHCERGFTGDGVHHCNQTCYNECRQGRCSGSPLFECECSLGWTSDPATLVLS----GVECDVDCGCNFHSTCIT-APGICDQCQDWTTGPHCEHCKPGSFGSALARGDGCVPCQCNGHGDPLQGFCHNQTGQCYCTHHTQGPHCESCLPGYYGDPRDNGTCFSQCQGRSVLLSSSVPLSLSSSLGWHGAVGGHGGVGGHGGLSHCLWVLSVSQDLAPCMPGQSCPPVALTWHPDSHTHCTNSYVYVFDGLPRFLSNGVVHSHHNLIGAFCGTTRMEPITVEATSGVVSVYFEANVTSGRAQGFNASFWVKRCGNGSTDEGTVISAECQAGAQCINGLCECPHGLGGPQCDRPVCPGSCGAEEGRGTCNMNLGLCVCTEG-WAGSDCSSISDTDSLVWETLLDTQLS---VNKAHRFLRRMGHSLMSSPQGTLWMYGGLSLSEGILGNVYRYSVADRRWTEVLTSSVE-ESSMPLPRYHHASALVYYQFPISGSHSATRNLMFVVGGVTKE-GVANDTWCLNLDSQEWKQYKSS-----------VLPPVAGHTLTVR---KGSSVLLIGGYSPENGFNHHLLEFSPQSGNWTIALHTGTPPTGLYGHSAVYHEQTDAVYVFGGYRFHVEAVEPSGELYSLYYPNLTWSLLVPSQGNK--------------------------------------------------------PLSRFFHAAALVKDTMVIVGGRTGEEDYSNTVSLYQINCNTWIQPVSS----VGEPVNSSVSLAMTVWGD-RLFLSGGFNG-VTLGRFLTLSLPSDPCILLPTPEACNSSTGSCVWCRGTCASSDAAERLGCTLGLSTCSPTP---------RSPDQCRRLKTCSECLARHPKTFSSP--VQSALQCKWCTNCPEG-ACISSSVSCTSEHDCRINQREIFLSSNCTETSCEASDCPKCTASGKCMWTRQFKRTGETRRILSVNPTYDWTCFSYALLNVSPMQVESSPPMPCPEPCHEIKTCSQCLSSRGSDGGWQRCVWSMALQQCMSPSFVPLRCEAGQCGRLLSD--EDSCSPQCFQLTQCSQCISRPQCGWCAGRGGNGSGRCLQGGLNG-----------------VSEAL-CPQWNSSWSFLHCPEEDECSNGHHHCN-VTQDCHDLPEGYHCTCRQGYVLSSVSGQCEPVCAQGCVNGTCISPGICQCHFGFVGENCSSQCRCNKHSNCKSISQLDTCLECKNNTKGQHCDKCKPLFVGSAMGGGMCRPCREFCRGNSDICLSKDEHNKAMENPKDYPLDRESIEQWATEGPTEDHAVCVSCQNNSVGDKCESCLSGYFLLQG----KCEKCQCNGHADTCNEHDGTGCPCQNNTETSSCLSSP--QNDRKECYRQQCAKCKESFNGNPVNGRQCYRQFNVDSECCFDPTSQVNCFHEPNIRNLLRGRTVFFSAQPKFTNVDIRVTIDVTFGEVEVYVSNSHDTFIVQVDRQSGVHTIKIEDEATSATASRGEKEVPLAPPSPM--------KVFANSSSALLGTLSAKLQGS-----------------EREVREERAEGLITYITVWKPQTVLIVRGVRDRVVITFPHEVHSLKSSRFFIALRGVGTETHNGE-----SQGLLFLRQDQAHIDLFVFFSVFFSCFFLFLSVCVLLWKVKQFLDFRREQRRHIQEMTKMASRPFAKLTVYLEPEEPQLVYLPSAGGGSAVSLAHVRTGKLGGMVMGQRGRPGALSYKHDPGTGTATHHHHHLALSGGNNGQHLPLHYLNAHHYAPSSTANPTSHHQHHYPSSHGSYQHFCRSDPFLSQLMGFSYSSFKVGPITLEPTDDGMAGVATVLIQLPGGILAPNRACLGSALVTLRQNLQEYCGHGG--AGTHPGAGGGRKGLLGHQHLTTMAM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLT6-1", "uniprot_id": "Q9VLT6_DROME", "id": "Q9VLT6-1", "name": "", "aln": "MYALLATLTFWTLVLQTEQAHPSTSPSAPCDRSRKVFTEPYGEISDGPSGFNYTQDSHCEWLIKARNDSQYITLTFHSMGTECSYDYIYVYDGDSFNSTLLGSFSGRTQPQRLVARSGSMLILMYSDTNYVLDGFRASYYISNCLNNCHNHGKCVGH--QCVCHGEWVGPDCEDEACPQRCGE-SQGRGRCQKSICHCSRGYSGRLCDLSDHPAGSS--WRWLATDAEGMTARAAHSAVYMEDEDALYVFGGYDLNNVISTLQIYRFSTSQWEDEWGIALQSRRHFYHPQKIDHTLLKAVLQHKNEDEAKLWGLNSDVSFFRNILYTLAESNLHQRRTRSSLPLTIVNANSTDEELNEYLEDILEEVTDHKPHGRYGHAADSVPGGFVIYGGKHANGSFYSDLWQYNNTESGGKWKQMA--IRSAVKPPALARHTLNTAG-SYLYIFGGSLETGEFSSSVYRIPLPLSEDSQWELVQPRGGKTLDVRLAAHSTVYYKATNSLIVFGGIMTSLARFSKLSDRIYAFQLDQMHWTEILYPRTALRDTNIPRERAFHTATISGNYMVVFGGYTHRHNKDEICYDNQMYWYHLSCHIWINQVVSADDS----LYPKPQGVFAHAAALRRNHTLLIVGGYHGNVNADLFAYELPQVLRVENTLYNPEISCRLHSSHTACLSNPECGWCSADSSCYGRTIGANCTTNLQTTRCPGICPSLGDCHSCLVHGSQWGKSSGNKAAFSVASKLGLNECTWCVQNAKCHHRDDNYGICGD----SSGWWGDKGTEIRRPSLCTSTDRRPGLTYIKYHFPINYTMPDYVGIVNATMVDFASPPFTTYFEHKLEGEMLARLVGFVRPQHQWNNSAIQVCTSYSSAVLRAGLGLNLDELVNVTTQSSNQSYCSNVQLPTTEQPFTIDFQTRRR---IGGNGIYN---AYQKTKMELQHLHNGQLN--AFTFEYLEPYYSGKCTQYSNCLHCLTDASCAWCPLTNICHLRSVNETEVCKMETLDTFHWSYLISQPSQCSNCTNYVSCEACARSGECEWWTEDAR-----CGRIGKTNSSVRAVEHCPRSCRERHGCQECLGERGRCVWCEASAQCFSFSVYTSEYQFGMCREWVDQVVSRQTQEIADHKPQQTPHFLQQQCKSCEQHRNCSSCLRTLSCGWCFDRDNPIEGICMQGDFSYS----AGNCSLALNSSSHH-------------------------------DAEWAYAQCPDVDECGLGLHDCHKEAKCTNTQGSYNCHCRRGYIGDGKFSCVRTCYELCQNGNCSGPPDYTCRCALGWT-------------GADCGLSCGCNNHSTCNE-RLGKCDQCQDWSEGEKCERCRQGSYGNATAPH-GCLPCECNGHGNQDLGVCNVSNGECYCKDNTQGLNCELCAPGYYGDPRGGGKCYYQCESRGILTNIGKSAIGSYQS-------YRSPWGASLEVKECLWILQP----KTLQAEKSLLQLEFQWQS-LAMDCDENAVYIYDSLPDLTG----ATQQNQLLAVVCAPYSSPRIIEARSSHVTVHYKQGSER-RHFGFNALYSVMNCVAG---------SCISPHICDAQQRCVCPAGYVGASCEIEICPSNCNAKRMQGFCDTEYGRCICSNANYAGADCGTLVQRNHLVMTELFNTQLLSESLEHLRKTIPRFGHSVNADRRGSLWMFGGYSPNHGPLNDFRQFDTKNSTWLQVTVESSTPEDRMPLGRYFHASEIYVK-----------KQIIYIYGGIGANSQLLNDFWMFSIQNQRWSQIKVEVEPPEADYEVDVPPPLAGHTLTHIRYQEHESLILLGGLSLNKSRPLELWEFNLDTGRWQQLAAVGARMPVLYGHTSVYHQETNSVYLFGGY-----STEPQSNLYALDLQKLSWTELPSFRELN--------------------------------------------------SPASLLPRARYFHSAVTTEHYMILYGGRTQPFNGTDVLIAYVYACNQWVRLTEDVELIGRVPASSYAEDMAIDPDTGAIYVIGGWDGSSTHSHVTKITLPDDICQLWSNGKYQCRHYMGCSYCTIQNTYSYSSHCFSHGR--TPCANHNGTLVVNNGAACDDDWMASRNCSSFATCGACLAAWPTHQEVAPVCHWCDDCGIRGRCVPAGVDCGRRSAWCNKELSVGVLGLCPLPQCYQLSCESCMLQPQCNWARNELGT--------------VECIAKELVEKNQYRVVES----CPLPCHTYENCSLCLS-QTPTQDHQECKWSTMLNLCLTPSSQPLLCAGGVCGLVLEASELQRCPEPCHVYTQCSSCLEHAHCGWCAREGFNGDGICTEGALEHKQEHPSGSTCDLIYASWRNDSQLTHADVVSWHYVQCPAENECINGHHNCDTVSEQCIDLDTAVGYKCVCAQGYREEQGACLPVCSQGCVRGNCVSPDQCQCDFGYVGANCSIQCLCNGHSNCESSSRLDICLKCHNNTMGEQCEKCQPLFVGNPREGHACQPCLDYCHGHSDVCVAYD------ADPAVFNMTRSELERILQEGPAYN-ATCLRCGNHTAGDRCDSCLTGYFRGSEDLHKECRPCQCHGHGNICDPVTGEKCNCANNTESDATCTAGGGKNSAQLCWMVQCSKCRDSYAGNPTDGHQCYKQITVESRMCFDAKPIEECKSKP--AALKPGQTVFFVIQPRFMNVDIRIIIDVTQGELDVFMSPQDDSFIVETNETTGYHEIFLDNRYNWGPKIKREHPLNVALPRHDNVTIQKLFSPERRIGGGGLGGGGGERIGANTYYVPQLQDCKSHGGHNFIVKDQHAKDLSTHVTLNHCNTLLRLFGLKNRLVLTLPQHAHNLSATRFFIALRASSGPE--------PSYGSVVFRQDQLHIDLFVFFSVFFSCFFLFLAVCVIVWKVKQAADLRRARRQHVVEMLHLAKRPFAQIFLASNGLDMD-----SPQPTSSSSSARAMR----------------------------QRARQALLLQEQSAGDSQSVMHHSTRRQS------------------------------------------SRIMMVAIEPTFDNLAAVGTVFISLPGRSRAPLSIALGSTLISYSRQYPLNTRHFMRAQRGQNVANHPA--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : . :. *. .*:*: * ::**.. **: :.:***** * . .: * * * :.***:***::****** ...**.*:** * * : * **.**: ::**:** * **.*:: :* * ..* .**:* * *. * * ** *. * . :* * *. *: *: *:* .: * ::: :.* . :..:: . : :*** ***..: * :*.**:. **. * *:.*.* * :*: **: *: : .*:* : ..*: :. .: .* ** *: .. :**: ** . ***.::*: * . ** * * **: :.** ::: .:.:*:*.** .: **** : *:::: ** : : *******:*:: ******:** .* * :* **:: :::***.** *:. * ::*.**: . .**:.*** * ..**.**::* .: * ...: * :***.**.. * :: * *: *.**::**... . : . ***:* .* :: : : **** : * : . *** :.:: * * : ** *.*:.:* : : ... :: : : *: . . : . * : :: :* : :. . :* . : * . : .* * . ::: * :.* . ::* :***: * *:.* .** **:* .*.** *.**. * *: * *. * :: .* **::. *** . : *.* *: ..::: ** * :* * :**.: .:*.**::: ** *:.* :.: .* ** * *.* * :*:.* .* .**:: .**** : .** * *::**:. . *** : . * *:*. ****:** *** ** *.* ** **:***.**: *** * :** : * :* ***.* : * * **** . *. .***. ** * * **:****: * :**:*: **:*.* . ** **:*****: * *. .* *:* .:*:* :*: * ******** .*.*: :* .*.:* . . * .. :. *:*::. . . : : : . * . * :*.:* : . :.:. : *. * ::* *. : :::: . **** .* * * ** * *. * :** .*.*. * *: . * *:*::. :.*.**.: : . ** *::::* : : : *:**:: . .:***:** . .* *.:. ::.. : * :: . : . * * .**: : ::: **: : * * :.: . .* * * *.:****** . *::*:** * ::. .* *:. : * *: . ****::***: *:::*:***: . *. :**:* . :*: * . : : * .* **::. . *:: ***: : :. : * ** *: * .. . . ::: **:.* : .:. ::** * * * .. : .* :* . :. :. ..*: . :: :.**. : . *:** :* *: . .* . :: .: . *. . * .* .* . :* *:*: * *:: *:: . * .* ** *** .*: ** : . . *.* ** *: *::** ** * .* ** :* : *. * ***: *: :.:***** * :*.* * :*.*. :. ** :: ** *:** ****.*: :::* * . .* . . * * ***:****.*.*:.*. *:*.**:** *** :* ** **:* . . * ** *:*:* *.:*::* *****.. * *:** :*:*:*.:*:: . :* : : ..:* ***: : *.*: * *:: *::*:*** *** . :* ***:**.: *: * * * ****:. : .. : *: **:**::*: *.* .*:***: :.*:.. *:*... :* :* * *:**:* **:* *****: :*** * :::::* . *:*:*.. :* * : :: . * . . * .. : *:: ...* *::*: . .::* : .:::*:*:* *:. * *.::**:: * . . * * :.:**** *******************::**::**.** * *: :*:*: ** ::*.****:: : .. .: . * * * . * .: : :::*** *.:*.*.*:::.*** ** .***:*:: :. . ", "identical_positions": 774, "similar_positions": 750, "identity": "24.26%" }, { "cls_id": "homologset.agr.RGD:621191", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P83731-1", "uniprot_id": "RL24_HUMAN", "id": "P83731-1", "name": "Large ribosomal subunit protein eL24", "aln": "MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEIQKKRTRRAVKFQRAITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQASKKTAMAAAKAPTKAAP-KQKIVKPVKVSAPRVGGKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83732-1", "uniprot_id": "RL24_RAT", "id": "P83732-1", "name": "Large ribosomal subunit protein eL24", "aln": "MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEIQKKRTRRAVKFQRAITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQASKKTAMAAAKAPTKAAP-KQKIVKPVKVSAPRVGGKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BP67-1", "uniprot_id": "RL24_MOUSE", "id": "Q8BP67-1", "name": "Large ribosomal subunit protein eL24", "aln": "MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEIQKKRTRRAVKFQRAITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQASKKTAMAAAKAPTKAAP-KQKIVKPVKVSAPRVGGKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8JGR4-1", "uniprot_id": "RL24_DANRE", "id": "Q8JGR4-1", "name": "Large ribosomal subunit protein eL24", "aln": "MKVELCSFSGYKIYPGHGRRYARVDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEVSKKRTRRAVKFQRAITGASLAEILAKRNQKPEVRKAQREQAIRAAKEAKKAKQATKKQTTQSSKAPAKSAQ-KQKIAKPMKVSAPRVGGKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJY6-1", "uniprot_id": "RL24_DROME", "id": "Q9VJY6-1", "name": "Large ribosomal subunit protein eL24", "aln": "MKIGLCAFSGYKIYPGHGKTMVKIDGKSFTFLDKKCERSYLMKRNPRKVTWTVLYRRKHRKGIEEEASKKRTRRTQKFQRAIVGASLAEILAKRNMKPEVRKAQRDQAIKVAKEQKRAVKAAKKAAAPAP--AKKSAP-KQKAAKVTQKAAPRVGGKR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24000-1", "uniprot_id": "RL24B_YEAST", "id": "P24000-1", "name": "Large ribosomal subunit protein eL24B", "aln": "MKVEVDSFSGAKIYPGRGTLFVRGDSKIFRFQNSKSASLFKQRKNPRRIAWTVLFRKHHKKGITEEVAKKRSRKTVKAQRPITGASLDLIKERRSLKPEVRKANREEKLKANKEKKRAEKAARKAEKAKSAGVQGSKVSKQQAKGAFQKVAATSR---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04449-1", "uniprot_id": "RL24A_YEAST", "id": "P04449-1", "name": "Large ribosomal subunit protein eL24A", "aln": "MKVEIDSFSGAKIYPGRGTLFVRGDSKIFRFQNSKSASLFKQRKNPRRIAWTVLFRKHHKKGITEEVAKKRSRKTVKAQRPITGASLDLIKERRSLKPEVRKANREEKLKANKEKKKAEKAARKAEKAKSAGTQSSKFSKQQAKGAFQKVAATSR---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: : :*** *****:* .: *.* * * : *. : ::***:: ****:*::*:** ** ***:*:: * **.*.**** * :*. *******:*:: ::. ** *:* :*::* . : **: : *. ", "identical_positions": 60, "similar_positions": 40, "identity": "37.97%" }, { "cls_id": "homologset.agr.RGD:621192", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61353-1", "uniprot_id": "RL27_HUMAN", "id": "P61353-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61354-1", "uniprot_id": "RL27_RAT", "id": "P61354-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61358-1", "uniprot_id": "RL27_MOUSE", "id": "P61358-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7ZV82-1", "uniprot_id": "RL27_DANRE", "id": "Q7ZV82-1", "name": "Large ribosomal subunit protein eL27", "aln": "MGKFMKPGKVVMVLAGRYAGRKAVIVKNIDDGTADRPYSHALVAGIDRYPRKVTATMGKKKIAKRSKIKAFVKVFNYNHLMPTRYSV-DIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBN5-1", "uniprot_id": "Q9VBN5_DROME", "id": "Q9VBN5-1", "name": "60S ribosomal protein L27", "aln": "MRKIMKQGKIVIVLSGRYAGRKAIIVKTHDDGTPEKPFGHALVAGIDRYPRKVTKKMGKNKLKKKSKVKPFLKSLNYNHLMPTRYTAHDISFEKLSP-KD-LKDPVKRKTHRFQTRVKFESVYKEGKNKWFFQKLRF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C2H6-1", "uniprot_id": "RL27A_YEAST", "id": "P0C2H6-1", "name": "Large ribosomal subunit protein eL27A", "aln": "MAKFLKAGKVAVVVRGRYAGKKVVIVKPHDEGSKSHPFGHALVAGIERYPLKVTKKHGAKKVAKRTKIKPFIKVVNYNHLLPTRYTL-DVEAFKSVVSTETFEQPSQREEAKKVVKKAFEERHQAGKNQWFFSKLRF", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0C2H7-1", "uniprot_id": "RL27B_YEAST", "id": "P0C2H7-1", "name": "Large ribosomal subunit protein eL27B", "aln": "MAKFLKAGKVAVVVRGRYAGKKVVIVKPHDEGSKSHPFGHALVAGIERYPSKVTKKHGAKKVAKRTKIKPFIKVVNYNHLLPTRYTL-DVEAFKSVVSTETFEQPSQREEAKKVVKKAFEERHQAGKNQWFFSKLRF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *::* **:.:*: ***:*:*.:*** *:*: .:*:.*******:*** *** * :*: *::*:*.*:* *****:****: *: * .: :.:* :. : .: **. :: ***:***.****", "identical_positions": 61, "similar_positions": 42, "identity": "44.53%" }, { "cls_id": "homologset.agr.RGD:621193", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17702-1", "uniprot_id": "RL28_RAT", "id": "P17702-1", "name": "Large ribosomal subunit protein eL28", "aln": "--MSAHLQWMVVRNCSSFLIKRN--KQTYSTEPNNLKARNSFRYNGLIHRKTVGVEAWPDGKGVVVVMKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNKYRPDLRMAAIRRASAILRSQKPVVVKRKRTRPTKSS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41105-1", "uniprot_id": "RL28_MOUSE", "id": "P41105-1", "name": "Large ribosomal subunit protein eL28", "aln": "--MSAHLQWMVVRNCSSFLIKRN--KQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVMKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNKYRPDLRMAAIRRASAILRSQKPVVVKRKRTRPTKSS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46779-1", "uniprot_id": "RL28_HUMAN", "id": "P46779-1", "name": "Large ribosomal subunit protein eL28", "aln": "--MSAHLQWMVVRNCSSFLIKRN--KQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNKYRPDLRMAAIRRASAILRSQKPVMVKRKRTRPTKSS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZS5-1", "uniprot_id": "RL28_DROME", "id": "Q9VZS5-1", "name": "Large ribosomal subunit protein eL28", "aln": "MATSSHLNWLIIRNNNAFLLKKRDVKKPFSTEPNNLASVSSYRYSGIVHKKTLGVVPAADKKGFTAVLKKGKYAQRPAKNTVRVDFKAGPRRSLKKLKNLLIGSKYRKDLTQAALRRASAVLRSQKPAPVKGKKAEFAKGKKPE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**:*:::** .:**:*:. *:.:******* : .*:**.*::*:**:** . .* **...*:*: . ::**.. **. :: ..* :*..::::: .*** ** **:*****:******. ** *::. :*.. ", "identical_positions": 59, "similar_positions": 56, "identity": "40.97%" }, { "cls_id": "homologset.agr.RGD:621194", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUK5-1", "uniprot_id": "INHBC_RAT", "id": "Q9WUK5-1", "name": "Inhibin beta C chain", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSLLLALLFLTLATVVN------------LKTDGPCPACWG-----------------------------------ATFDLESHRELLLDLAKKSILDKLHLSQRPILSRPVSREALKTALRRLRG---------------------------TRAETLLE-----HDQRQE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YEIISFADTGLSNINQTRLEFHFS-DRTTGG-VEVLQTRFMFFMQLPP-------------------------NTTQTMNIRVLVLRP--------YDTNLTLTSQYMLQVDAS----GWYQLLLGPEAQAACSQG-HLTLELVPESQ----------------LAHSSLILDGVSHRPFVAAQVRVEGKHRVRRRGINCQGLSR-MCCRQEFFVDFREIGWHDWIIQPEGYAMNFCTGQCPLHVAGMPGISASFHTAVLNLLKANTDAGTARRGSCCVPTSRRPLSLLYYDRDSNIVKTDIPDMVVEACGCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P55104-1", "uniprot_id": "INHBC_MOUSE", "id": "P55104-1", "name": "Inhibin beta C chain", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSLLLALLFLTPTTVVN------------PKTEGPCPACWG-----------------------------------AIFDLESQRELLLDLAKKSILDKLHLSQRPILSRPVSRGALKTALQRLRG---------------------------PRRETLLE-----HDQRQEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YEIISFADTDLSSINQTRLEFHFS-GRMASG-MEVRQTRFMFFVQFPH-------------------------NATQTMNIRVLVLRP--------YDTNLTLTSQYVVQVNAS----GWYQLLLGPEAQAACSQG-HLTLELVPESQ----------------VAHSSLILGWFSHRPFVAAQVRVEGKHRVRRRGIDCQGASR-MCCRQEFFVDFREIGWNDWIIQPEGYAMNFCTGQCPLHVAGMPGISASFHTAVLNLLKANAAAGTTGRGSCCVPTSRRPLSLLYYDRDSNIVKTDIPDMVVEACGCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55103-1", "uniprot_id": "INHBC_HUMAN", "id": "P55103-1", "name": "Inhibin beta C chain", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSSLLLAFLLLAPTTVAT------------PRAGGQCPACGG-----------------------------------PTLELESQRELLLDLAKRSILDKLHLTQRPTLNRPVSRAALRTALQHLHG---------------------------VPQGALLE-----DNREQE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CEIISFAETGLSTINQTRLDFHFSSDRTAGD-REVQQASLMFFVQLPS-------------------------NTTWTLKVRVLVLGP--------HNTNLTLATQYLLEVDAS----GWHQLPLGPEAQAACSQG-HLTLELVLEGQ----------------VAQSSVILGGAAHRPFVAARVRVGGKHQIHRRGIDCQGGSR-MCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O61643-1", "uniprot_id": "INHB_DROME", "id": "O61643-1", "name": "Inhibin beta chain", "aln": "MRFAFDSNHSQSGAPFKGSRCFFNCQCICCRQGCCVVVVKCCCCFNLNCCNSLGSRKSFPQPAAMRKKVADLEVLRVSRFVAVILVLARWVTAVATLLTSCILLDIFSVPGQSGVADRSQASSRTVHVSVPTTPNETPSSTSETKLKLLYGYTSYDINNDQQVKSNNLCRVLCKSRNRKRQRRRRRRRNHRRRRHRYTKRLHHLMQDNMSGFEQRLNFSDAKCQS--LETNYGTNYDLVQGGKLFSQSERSLLVSPLREIEAPWPAIHGSMRNCSKIKRNRANLIWLLIGLVWFEVKLINCNGISSSNYYASNLESHKGCTLCHESGKPNIYTDKDNPHTDYNIYNKYHSNNNFNKKTNQPHNNIAPSDEVRLESIKRQILTKLGLSHKPNVSHPLPKQFIWETIYRVDGGRMIPNNAFGSSGKNLDQKTIKLRAFASPGSHLFNGRGGRTDQRSERDPSHHKYRSPFDFTFNISKNNVYGKVLRNRSLERIDKKNSFLNGWTENRQLKINSQIASMPIELKSHHNSSPKELKSGAVRKVNGINGTQMNENALKKSTYPIDINHSIDNKTHTGKNGEMSHNDYEYFNDYSVQTHDKNRYHEGRSSIGYQPAIHNIEYENQKGHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRASFQVDPKNL----GWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLHLFQTSKLRGNSSDYLSTNPNRPFLVLHTESSRTRRVRRRAVDCGGALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFR-TPDTFQTFHAHFIEEYRKMGLMN--GMRPCCAPIKFSSMSLIYYG-DDGIIKRDLPKMVVDECGCP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQG9-1", "uniprot_id": "INHBA_DROME", "id": "Q9VQG9-1", "name": "Protein dawdle", "aln": "-------------------------------------MAKYFIALVLLVCLALENRNVYNRLHARSHPSSRGDILRP--------------------------------------HPKHQPHPHVQHTSQQLQQQHHIRQQRSRQLKHLEPDPTSEEDDVPITKREYYARLRRHVIHKRQHLLQQELSYNHPGSHSEQLKVPRLWQHLMEQEEKAHRHVSPPVELPIMYGDAPEESSLSSDDHFDDLSPLDFVRNELMAEDQQNQEKDLDLDLDLDQQPETPIEPELPLGERNITISVKSS---------------AGGCPKCESNRQ-------------------------------VEHITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPKPIFDGMTLSHPD-------------------------DSTKNKELDDYYARTSKKFILLN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------REEVECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVN---------------STSAQQTIVVSEVEVDQ--------QKDSKYLSAAKTIAIQSVNVQDEWMKIDIEWPIKHWISGHELSHLIQITCGG-------------CDVSDMEEIISVDKDYRPFIVIDMQNRRRKSRQKRSINCSSGMT-ECCREHLYISFRDIGWSNWILKPEGYNAYFCRGSCSSVAS--VTQAASHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQLVVMDSSNTATVKTLPNMVVESCGCR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. : *. * .: :: *:.** ** *.. * :. : : :: .:. . .: . . : * . . .: : : : : .. : : . : . : : : . * :: : : . * : .. ***:. . : ::*.::* . **:: :::.*: :** :**: *.** :* *.*. :.*: .:: .**.. .:.*: . .. :*.***: *** ", "identical_positions": 42, "similar_positions": 97, "identity": "4.39%" }, { "cls_id": "homologset.agr.RGD:621195", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91YR9-1", "uniprot_id": "PTGR1_MOUSE", "id": "Q91YR9-1", "name": "Prostaglandin reductase 1", "aln": "MVQAKSWTLK--------KHFEGFPTDGNFELKTTELP--PLNNG----------------------------EVLLEALFLSVDPYMRVAAKK--------LKEGDRMMGEQVARVVESKNSAFPKGTIVAALLGWTSHSISDGNG-----LTKLPVEWPDKLPLSLALGTVGMPGLTAYFGLLDICGVKG-----GETVMVSAAAGAVGSVVGQIAK--LKGCKVVGTAGSDEKVAYLKKLGFDVAFNYKTVKSLEEALRTAS--PDGYDCYFDNVGGEFSNAVILQMKTFGRIAICGAISQYNRTGPCPQGPAPEVVIYQQLRMEGFIVNRWQGEVRQKALTELMNWVSEGKVQCHEYVTEG------FEKMPAAFMGMLKGENLGKTIVKA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97584-1", "uniprot_id": "PTGR1_RAT", "id": "P97584-1", "name": "Prostaglandin reductase 1", "aln": "MVQAKTWTLK--------KHFEGFPTDSNFELRTTELP--PLNNG----------------------------EVLLEALFLSVDPYMRVAAKK--------LKEGDSMMGEQVARVVESKNSAFPTGTIVVALLGWTSHSISDGNG-----LRKLPAEWPDKLPLSLALGTVGMPGLTAYFGLLDICGLKG-----GETVLVNAAAGAVGSVVGQIAK--LKGCKVVGTAGSDEKVAYLKKLGFDVAFNYKTVKSLEEALRTAS--PDGYDCYFDNVGGEFSNTVILQMKTFGRIAICGAISQYNRTGPCPPGPSPEVIIYQQLRMEGFIVTRWQGEVRQKALTDLMNWVSEGKIRYHEYITEG------FEKMPAAFMGMLKGDNLGKTIVKA----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14914-1", "uniprot_id": "PTGR1_HUMAN", "id": "Q14914-1", "name": "Prostaglandin reductase 1", "aln": "MVRTKTWTLK--------KHFVGYPTNSDFELKTAELP--PLKNG----------------------------EVLLEALFLTVDPYMRVAAKR--------LKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKD-----LEKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKG-----GETVMVNAAAGAVGSVVGQIAK--LKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKAS--PDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKEYIIEG------FENMPAAFMGMLKGDNLGKTIVKA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G442-1", "uniprot_id": "A0AC58G442_DANRE", "id": "A0AC58G442-1", "name": "Prostaglandin reductase 1", "aln": "MVKAKVWILK--------KHFEGFPKESNFELKEVDLP--ELQDGGMDNSCTLFSYMCNVSLIYQHFCCCCYLDVLVEAIYFSLDPYMRSLSKMF-------LKEGDVQYGTQLAKVLKSKDPEFPEGCYVVADCGWRTHTVTKAKGPRGPILTRIVSEWPTDIPMSLALGSLGMPGLTALYGLEEVCKIQP-----GQTVLVSAAAGTVGTVVGQICK--IKGCKVVGSAGGDDKVAYLKELGFDQAFNYKTVPSLEEALKNAS--PEGYDCYFESVGGPMFTAALKNMKPGGRIAVCGAIATYNDTTPQMCPYPHHEIIVRSLTIQGFMVTNYK-EKDEESVKRLLTWMKEGKLKTKEMVTVG------FDKLPIAFMKMLKGDGLGKAIVKV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03102-1", "uniprot_id": "YMN1_YEAST", "id": "Q03102-1", "name": "Uncharacterized membrane protein YML131W", "aln": "MVLAKQWVLKNLPTPGEPFNFHFHDPACTFELIEKELSSEQLKDG----------------------------ELLLETTYLSNDPAQKFWISSMDKNYAKGVQPGEIIPARGIGKVLASRNKAFSPGDYVSAVTGWTTHAIISQEN----VQGLRKLDKNKVGKLWWYLSVLGGTSLTAYFIFFTYAQLQEREEDYGKVYLISGAAGAVGTVCIQLALNVFKASKVIAIAGGPEKVAFVESFGDNVVGVDYKDPSFKQKLIEAAGGENTVDYFIDNVGSNVLEAGVLLLKQRAMLIACGAISAYNDPSKFVFKG-YSFILTKRLVVKGVLVTDNIDDFPK-ALDKLGSLVKHGKIDLLKSATLEDGTGDKFKNVPLIWKGLFSGVNKGKLITKVNNEE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :* * ** :* . *** :*. *::* ::*:*: ::: ** : . :: *: . :.:*: *:: :. * * * ** :*:: . :. : : *. :* ..*** : : . :: *:. ::..***:**:* *:. :*..**:. .*. :***:::.:* : . . *::: * *: : * :::.**. . : : :* . : ****: ** . :: : * ::..:* : : :: * . : .**: : *.::* : ::.* . ** *.*. ", "identical_positions": 72, "similar_positions": 116, "identity": "18.05%" }, { "cls_id": "homologset.agr.RGD:621196", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88959-1", "uniprot_id": "INHBE_RAT", "id": "O88959-1", "name": "Inhibin beta E chain", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGLSNVQLWTILLWALAWVQSTR------------------SACPSCGAPTLTPQGER--------------------------------ALVLELAKQQILEGLHLTSRPRITRPLPQAALTRALRRLQPRSMVPGNRE------------KVISFAT-----------------SIDKSTSTYRSVLTFQLSP----------------------------------------------LWSHHLYHAR------------------------------------------------------------------------------------------------------------------------------------------------------------------LWLHVPPSFPATLYLRIFGCGTTRCR-GSRTFLAEHQTTSSGWHALTLPSSGLRSEESGVTKLQLEFRPLDLNSTTARLP--------RLLLDTAGQQ--------------RPFLELKIRANEP-------------------GAGRARRRTPTCESETP-LCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPAGSSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08717-1", "uniprot_id": "INHBE_MOUSE", "id": "O08717-1", "name": "Inhibin beta E chain", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLPKAQLWLILLWALVWVQSTR------------------SACPSCGGPTLAPQGER--------------------------------ALVLELAKQQILEGLHLTSRPRITRPLPQAALTRALRRLQPKSMVPGNRE------------KVISFAT-----------------IIDKSTSTYRSMLTFQLSP----------------------------------------------LWSHHLYHAR------------------------------------------------------------------------------------------------------------------------------------------------------------------LWLHVPPSFPGTLYLRIFRCGTTRCR-GFRTFLAEHQTTSSGWHALTLPSSGLRSEDSGVVKLQLEFRPLDLNSTAAGLP--------RLLLDTAGQQ--------------RPFLELKIRANEP-------------------GAGRARRRTPTCEPETP-LCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPAGSSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58166-1", "uniprot_id": "INHBE_HUMAN", "id": "P58166-1", "name": "Inhibin beta E chain", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLPDVQLWLVLLWALVRAQGTG------------------SVCPSCGGSKLAPQAER--------------------------------ALVLELAKQQILDGLHLTSRPRITHPPPQAALTRALRRLQPGSVAPGNGE------------EVISFAT-----------------VTD-STSAYSSLLTFHLST----------------------------------------------PRSHHLYHAR------------------------------------------------------------------------------------------------------------------------------------------------------------------LWLHVLPTLPGTLCLRIFRWGPRRRRQGSRTLLAEHHITNLGWHTLTLPSSGLRGEKSGVLKLQLDCRPLEGNSTVTGQP--------RRLLDTAGHQ--------------QPFLELKIRANEP-------------------GAGRARRRTPTCEPATP-LCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O61643-1", "uniprot_id": "INHB_DROME", "id": "O61643-1", "name": "Inhibin beta chain", "aln": "MRFAFDSNHSQSGAPFKGSRCFFNCQCICCRQGCCVVVVKCCCCFNLNCCNSLGSRKSFPQPAAMRKKVADLEVLRVSRFVAVILVLARWVTAVATLLTSCILLDIFSVPGQSGVADRSQASSRTVHVSVPTTPNETPSSTSETKLKLLYGYTSYDINNDQQVKSNNLCRVLCKSRNRKRQRRRRRRRNHRRRRHRYTKRLHHLMQDNMSGFEQRLNFSDAKCQS--LETNYGTNYDLVQGGKLFSQSERSLLVSPLREIEAPWPAIHGSMRNCSKIKRNRANLIWLLIGLVWFEVKLINCNGISSSNYYASNLESHKGCTLCHESGKPNIYTDKDNPHTDYNIYNKYHSNNNFNKKTNQPHNNIAPSDEVRLESIKRQILTKLGLSHKPNVSHPLPKQFIWETIYRVDGGRMIPNNAFGSSGKNLDQKTIKLRAFASPGSHLFNGRGGRTDQRSERDPSHHKYRSPFDFTFNISKNNVYGKVLRNRSLERIDKKNSFLNGWTENRQLKINSQIASMPIELKSHHNSSPKELKSGAVRKVNGINGTQMNENALKKSTYPIDINHSIDNKTHTGKNGEMSHNDYEYFNDYSVQTHDKNRYHEGRSSIGYQPAIHNIEYENQKGHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGG---------RYSLHLFQTSKLRGNSSDYLSTNPNRPFLVLHTESSRTRRVRRRAVDCGGALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFR-TPDTFQTFHAHFIEEYRKMGLMNGMRPCCAPIKFSSMSLIYYGDDG-IIKRDLPKMVVDECGCP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQG9-1", "uniprot_id": "INHBA_DROME", "id": "Q9VQG9-1", "name": "Protein dawdle", "aln": "-------------------------------------MAKYFIALVLLVCLALENRNVYNRLHARSHPSSRGDILRP--------------------------------------HPKHQPHPHVQHTSQQLQQQHHIRQQRSRQLKHLEPDPTSEEDDVPITKREYYARLRRHVIHKRQHLLQQELSYNHPGSHSEQLKVPRLWQHLMEQEEKAHRHVSPPVELPIMYGDAPEESSLSSDDHFDDLSPLDFVRNELMAEDQQNQEKDLDLDLDLDQQPETPIEPELPLGERNITISVKSSAG---------------GCPKCESNRQVEHITEEQLT-------------------------------HLRIEFVKQQILEKLRLKESPKVSAVELPKPIFDGMTLSHPDDSTKNKELD-----------DYYARTS-------------KKFILLNREEVECNRARDGKSNPS--------------------------------------------MCFTFKIDDADAEG-----------------------------------------------------------------------------------------------------------------------------------------------------------------FDVSTAVLWLFKNKQNRTDTASVNSTSAQQTIVVSEVEVDQQKDSKYLSAAKTIAIQSVNVQDEWMKIDIEWPIKHWISG-HELSHLIQITCGGCDVSDMEEIISVDKDYRPFIVIDMQNRRR---------------------KSRQKRSINCSSGMT-ECCREHLYISFRDIGWSNWILKPEGYNAYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQLVVMDSSNTATVKTLPNMVVESCGCR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . * . .: : : :* *:*** * *. *.:: : : . .: . : :: : . . :.: . :. :. . .. . : : :: . : * : * .:: . ::*: * **:. *:.*: :** :**: *.** :* *.*. : : . .**.. .:.*: . .. :*.***: *** ", "identical_positions": 38, "similar_positions": 79, "identity": "3.96%" }, { "cls_id": "homologset.agr.RGD:621197", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPH2-1", "uniprot_id": "MRP_RAT", "id": "Q9EPH2-1", "name": "MARCKS-related protein", "aln": "MGSQSSKAPRGDVTAEEAAGASPAKANGQENGHVKSNGDLTPKGEGESPPVNGADEAAGA--------TGDAIEPAPPSQEAEAK--GEVAPKETPKKKKKFSFKKPFKLSGLSFKRNRK--EGGGDSSASSPTEEEQEQGEISACSD----EGTAQEGKAAATPESQEPQAKGAEASAVSKGGDAEEEAGPQAAEPSTPSGP--ESGPASASAENE---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28667-1", "uniprot_id": "MRP_MOUSE", "id": "P28667-1", "name": "MARCKS-related protein", "aln": "MGSQSSKAPRGDVTAEEAAGASPAKANGQENGHVRSNGDLTPKGEGESPPVNGTDEAAGA--------TGDAIEPAPPSQEAEAK--GEVAPKETPKKKKKFSFKKPFKLSGLSFKRNRK--EGGGDSSASSPTEEEQEQGEMSACSD----EGTAQEGKAAATPESQEPQAKGAEASAASKEGDTEEEAGPQAAEPSTPSGP--ESGPTPASAEQNE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49006-1", "uniprot_id": "MRP_HUMAN", "id": "P49006-1", "name": "MARCKS-related protein", "aln": "MGSQSSKAPRGDVTAEEAAGASPAKANGQENGHVKSNGDLSPKGEGESPPVNGTDEAAGA--------TGDAIEPAPPSQGAEAK--GEVPPKETPKKKKKFSFKKPFKLSGLSFKRNRK--EGGGDSSASSPTEEEQEQGEIGACSD----EGTAQEGKAAATPESQEPQAKGAEASAAS-----EEEAGPQATEPSTPSGP--ESGPTPASAEQNE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PD99-1", "uniprot_id": "MRPA_DANRE", "id": "Q6PD99-1", "name": "MARCKS-related protein 1-A", "aln": "MGAQLTKGEATVEGKAVAD-----KANGQENGHVKTNGDVSTKPDGEAVAADGNGTAEVAKDEAPKTEEGDGIEAAPATEAEASKSDGEAAKET--KKKKKFSLKNSFKFKGISLKKNKKASEEAAEAVATPTTAEDKPEENGQAATETKEEEPAAETNETPAPEAEAEPKVEEAEPKAEEPAQQTETAPTEETTKSEESPAPVEETTPTESSDPEPAAE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NWH2-1", "uniprot_id": "MRPB_DANRE", "id": "Q6NWH2-1", "name": "MARCKS-related protein 1-B", "aln": "MGSQASKGGVAVEGKAAAADPAAVKTNGQENGHVKTNGDVSAKAEGDAATT--NGSAEAAKESE--AGAGDAIEPAPAAEGEAAKPEGEATKETPKKKKKKFSLKNSFKFKGISLKKSKKNAEVKEEAAAAAPATEEKPEENGAATEEKKEEE--AKAEETPAAPVET-PKAEEPAAKAEEPAAAKEEAAAPAVEATKQT----EETNSTPAPSEQKE--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* :*. * *:********::***::.* :*:: .. . * * **.**.**.:: :* **.. : *******:*:.**:.*:*:*:.:* * :: *:..: *:: : : * : * *: ::.*. . *:.: . ..* . * . . .. . *: .: :. : ", "identical_positions": 55, "similar_positions": 69, "identity": "25.0%" }, { "cls_id": "homologset.agr.RGD:621198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q641W4-1", "uniprot_id": "RFC2_RAT", "id": "Q641W4-1", "name": "Replication factor C subunit 2", "aln": "MEVQESGSGSAESGTQE--PSPVPSKT---TGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKIL-AHLWHLGYSPEDVIGNIFRVCKTFP-MAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARLCQKTMAPVAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUK4-1", "uniprot_id": "RFC2_MOUSE", "id": "Q9WUK4-1", "name": "Replication factor C subunit 2", "aln": "MEVQESGCDPSESGAQE--PSPVPSKT---AGHYELPWVEKYRPLKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLTRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKIL-AHLWHLGYSPEDVIGNIFRVCKTFP-MAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARLCQKTMAPVAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35250-1", "uniprot_id": "RFC2_HUMAN", "id": "P35250-1", "name": "Replication factor C subunit 2", "aln": "MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKIL-AHLWHLGYSPEDIIGNIFRVCKTFQ-MAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N4C3-1", "uniprot_id": "A0A8M1N4C3_DANRE", "id": "A0A8M1N4C3-1", "name": "Replication factor C subunit 2", "aln": "MDVEMKETDSEQTQADGP-PKKDETAPKPTTTAYELPWVEKYRPLKLNEIVGNEETVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPAMKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYSKLRDEQIMMRLTEVVEKENLHVTNDGLEAIIFTAQGDMRQALNNLQSTNSGFGYINSENVFKVCDEPHPLLVKSMLEHCVNANIDEAYKII-EQLWSLGYSPEDIIGNIFRVCKTFQ-MAEYLKLEYIKEIGYTHMKVAEGVNSLLQMAGLLGRLCRKTATPEAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53034-1", "uniprot_id": "RFC2_DROME", "id": "P53034-1", "name": "Replication factor C subunit 2", "aln": "MPEE------PEKTADD--------------KRSHLPWIEKYRPVKFKEIVGNEDTVARLSVFATQGNAPNIIIAGPPGVGKTTTIQCLARILLGDSYKEAVLELNASNERGIDVVRNKIKMFAQQKVTLPRGRHKIVILDEADSMTEGAQQALRRTMEIYSSTTRFALACNTSEKIIEPIQSRCAMLRFTKLSDAQVLAKLIEVAKWEKLNYTEDGLEAIVFTAQGDMRQGLNNLQSTAQGFGDITAENVFKVCDEPHPKLLEEMIHHCAANDIHKAYKIL-AKLWKLGYSPEDIIANIFRVCKRIN-IDEHLKLDFIREIGITHMKIIDGINSLLQLTALLAKLCIAAEKH---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40339-1", "uniprot_id": "RFC4_YEAST", "id": "P40339-1", "name": "Replication factor C subunit 4", "aln": "MSKTLS---------------------------LQLPWVEKYRPQVLSDIVGNKETIDRLQQIAKDGNMPHMIISGMPGIGKTTSVHCLAHELLGRSYADGVLELNASDDRGIDVVRNQIKHFAQKKLHLPPGKHKIVILDEADSMTAGAQQALRRTMELYSNSTRFAFACNQSNKIIEPLQSRCAILRYSKLSDEDVLKRLLQIIKLEDVKYTNDGLEAIIFTAEGDMRQAINNLQSTVAGHGLVNADNVFKIVDSPHPLIVKKML---LASNLEDSIQILRTDLWKKGYSSIDIVTTSFRVTKNLAQVKESVRLEMIKEIGLTHMRILEGVGTYLQLASMLAKIHKLNNKA---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .***:***** :.:****::*: **. :* :** *::**:* ** ****:: ***: *** : :.:******::********:** ***:*: ** *:***:********* ***********:**.:****:*** *:*****:*****:**::** * ::: :* :: : * : *:******:***:*****.:****** *.* :.::****: *.*** :::.*: ::..: :*: .** ***. *:: . *** * : : * ::*: *:*** ***:: :*:.: **::.:*.:: ", "identical_positions": 164, "similar_positions": 93, "identity": "46.07%" }, { "cls_id": "homologset.agr.RGD:621199", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99P88-1", "uniprot_id": "NU155_MOUSE", "id": "Q99P88-1", "name": "Nuclear pore complex protein Nup155", "aln": "------------------------------------------------MP-SVLGSMMVASTSAAASLQEALENAGRLIDRQLQEDRMYPDLSELLMVS--------------APNSPTVSGMSDMDYP-LQGPGLLSVPSLPEISTIRR---VPLPPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSYANVQTGSGILNDSMCGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDG--CLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSED-------------------DPIVQIEIDNSRNILYTRSEKGVIQVYDLGHD-GQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIESSESLDCQLLAVTHAGVRLYFSTC-----------------------------PFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHKALYSKGILLMTASENEDNDILWCVNHDTFPFQKPMMETQMTTR--VDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGG-EAQMRFPATLPTPSN--VGPILG-SPMYSSSPVPSGSPYPNPSSLGTPSHGAQPPTMSTPMCAVGSPAMQAASMS---------------------------GLTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERVFKSSNREITAIESSVPVQLLESVLQELKG--------LQEFLDRNSQFSGGPLGNPNTTARVQQRLVGFMRPENGNTQQMQQELQRKFQEAQLSEKISLQAIQQLVRKSYQALALWKLLCEH-----------QFSVIVGELQKEFQEQLKITTFKDLVIRD---KEVTGALIASLINCYIRDNAAVDGISLHLQDTCPLLYSTDDAVCSKANELLQRSRQVQSKTERER--MLRESLKEYQKISN---QVDLPSVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDVVGLQTFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLAQRSKDELFSIALYNWLIQADLADKLLQIASPFLEPHLVRMARVDQNRVRYMDLLWRYYEKNRSFSSAARVLSKLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAIS-QLDSELMDITKLYGEFADPFKLAECKLAVIHCAGYSDPILVHTLWQDIIEKELNDSVALSSSDRMHALSLKLVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRVKSPLHLLDCIHVLLTRYVENPSLVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37199-1", "uniprot_id": "NU155_RAT", "id": "P37199-1", "name": "Nuclear pore complex protein Nup155", "aln": "------------------------------------------------MP-SMLGSMMVASTSAPS-LQEALENAGRLIDRQLQEDRMYPDLSELLMVS--------------APNSPTVSGMSDMDYP-LQGPGLLSVPSLPEISTIRR---VPLRLSWLNSLDTCSVTAMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSYANVQTGSGILNDSVCGGLQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDG--CLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSED-------------------DPIVQIEIDNSRNILYTRSEKGVIQVYDLGHD-GQGMSRVASVSQNAIVCAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTC-----------------------------PFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHKALYSKGILLMTASENEDNDILWCVNHDTFPFQKPMMETQMTTR--VDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGG-EAQMRFPATLPTPSN--VGPILG-SPMYSSSPVPTGSPYPNPSSLGTPSHGAQPPTMSTPMSAVGNPAMQAASLS---------------------------GLTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERVFKSSNREITAIESSVPIQLLESVLQELKG--------LQEFLDRNSQFSGGPLGNPNTTAKVQQRLLGVMRPENGNTQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEH-----------QFTVIVGELQKEFQEQLKITTFKDLVIRE---KEVTGALIASLINCYIRDNAAVDGISLHLQDTCPLLYSTDDAVCSKANELLQRSRQVQSKSERER--MLRESLKEYQKISN---QVDLPSVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDVVGLQTFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLAQRSKDELFSIALYNWLIQADLADKLLQIASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSSAARVLSKLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAIS-QLDSELMDITKLYGEFADPFKLAECKLAIIHCAGYSDPILVHTLWQDIIEKELSDSVTLSSSDRMHALSLKLVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRVKSPLHLLDCIHVLLTRYVENPSLVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75694-1", "uniprot_id": "NU155_HUMAN", "id": "O75694-1", "name": "Nuclear pore complex protein Nup155", "aln": "------------------------------------------------MPSSLLGAAMPASTSAAA-LQEALENAGRLIDRQLQEDRMYPDLSELLMVS--------------APNNPTVSGMSDMDYP-LQGPGLLSVPNLPEISSIRR---VPLPPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSYANLQTGSGVLNDSLSGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDG--CLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSED-------------------DPILQIAIDNSRNILYTRSEKGVIQVYDLGQD-GQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTC-----------------------------PFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHRALYSKGILLMAASENEDNDILWCVNHDTFPFQKPMMETQMTAG--VDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGG-EAQMRFPTTLPPPSN--VGPILG-SPVYSSSPVPSGSPYPNPSFLGTPSHGIQPPAMSTPVCALGNPATQATNMS---------------------------CVTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERIFKSGNREITAIESSVPCQLLESVLQELKG--------LQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFMRPENGNPQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEH-----------QFTIIVAELQKELQEQLKITTFKDLVIRD---KELTGALIASLINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKER--MLRESLKEYQKISN---QVDLSNVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVS-QLDSELMDITKLYGEFADPFKLAECKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V463-1", "uniprot_id": "NU154_DROME", "id": "Q9V463-1", "name": "Nuclear pore complex protein Nup154", "aln": "-------------------------------------------------------------MTLPQAQLDFFTTATSMLEWHYNLERNKPGLLELTGVS--------------QHGRATMSGLNDYDYQSLSFLKSDRTHNLQQMRTVTK---SAIPNEILEHFKHIKCHCTMGLFPEIGRAWLTIDSEIYIWTFNQTRDVAYYDGLSHLIVSVGLVKPKPGVFVQDVKYLLVLTTPIEVIVLGVTFG----------ESSYNEMQLMNRPVFVIGTDNVSISVIKGTDDGRIFLGGRDG--CLYEIYYQAESSWFGKRCKKINLSQGLVSYMVPSFLK-VFSEV-------------------DPIEHIEIDNSRKLLYVLTEKGVIEAWDISTS-YTTARRLGRITQNDITNQAVSLITTVDPSIFKSVKAICPLSADDADKLHLVAVTQCGVRLFFSTTSLNVKQQFGPAVPCSPGENTGFGQPAVQPPLSPNAEAPKGLYLLHVRLPPGYTPNATTNKPKQVHAAHYTEGTMLMITTQQHEQDLLWSLSSAPSVNFTYLVESTALES--LDGVVWGLAEVHEPSTPQRKSPLN---------------SARHARKVALLTNQGTHIIEVLKMVDVLRQILLSCNGPHHEEVKMFFQSQNQREACVTALLLATSDTYRGSDVALWAAQAFMLYGG-EPCYQHQKFLNASNRNMANQTLGPNTTNVRERQSMFMSTPMPNSVANSPVGFPGSQFNQPISPIGNMQPPQVAVS---------------------------NEN-SPIVFSAKHDGLYMYVSRMLHSVWQMRCVNEQFCSN--------LSQSECALLLSDLRSLRS--------FLEVHSVHDISSTTRVSFDNHLDRTNSYNTIMMG----NTLLPIPEQRVLSEQAQVEETRSLSALNLFVKHACEVISLWNILNSH-----------SFQLICVQLSPEHQKLLTCSTFRDLLITR---SEVCAFLIISLINLYLKDAAGVSEVSKNLRENCPNLYRHEDDVTYKATELLMNAKNCTSATEKEH--MLRTTLHMCKEAAP---TLPLHSICMQFISADFFEGVIELSAVCASKSDPEEVGVHFYNNGEPADDREGYTCFATRMAYYKEVQLMLDHIYQR---VCNKTHVQDKSINPLKGTAKASDAKNGATQTIPKIVAHTLKVKDPLIHITLYEWLLAHDMLKELLDVVEPSLGEFLRRSVSQNVDNVVLIDLLWKYYEKNSHHSQAAHILDNLAMTRSENINLEQRIEYLVRAVMCMRNGNVGSSLSN-GIFLKELEDKLDIARVQKSVLAAMTELASDKLEAATAVK-ELNYALYDITQLYQHFAEPFDLWECQLSILNCSHHNDPLLIESVWGQIINSVVDK--PGTTSERCNRLFTKIEILVREYGESGVCFPFAFLIRELEVKACQLRFPEGIVPEKLVSMNLDIELLLEYYSRMISMNERVWANEGNEWHLIQSVIRVVSLLADNAQSIWYRSKRRIVGKAQDIVAGCLNICYQKPD---TNRLQHSLKELQSQLQRLLI--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40064-1", "uniprot_id": "NU157_YEAST", "id": "P40064-1", "name": "Nucleoporin NUP157", "aln": "MYSTPLKKR-IDYDRETFTASASLGGNRLRNRPRD---------DQNNGKPNLSSRSFLSERKTRKDVLNKYGEAGNTIESELRDVTTHVKISGLTSSEPLQLASEFVQDLSFRDRNTPILDNPDYYSKGLDYNFSDEVGGLGAFTPFQRQQVTNIPDEVLSQVSNTEIKSDMGIFLELNYCWITSDNKLILWNINNSSEYHCIDEIEHTILKVKLVKPSPNTFVSSVENLLIVATLFDIYILTISFN-----------DRTHELNIFNTGLKVNVTGFNVSNIISYERTGQIFFTGATDGVNVWELQYNCSENLFNSKSNKICLTKSNLANLLPTKLIPSIPGGKLIQKVLEG----DAGTEEETISQLEVDQSRGVLHTLSTKSIVRSYLITSNGLVGPVLIDAAHIRRGMNALGVKNSPLLSNRAFKIAKIVSISMCENNDLFLAVITTTGVRLYFKGS--------------------------------ISRRSIGSLKLDSVKFPPTSIS----------SSLEQNKSFIIGHHPLNTHDTGPLSTQKASSTYINTTCASTIISPGIYFTCVRKRANSGELSKGITNKALLENKE--------------EHKLYVSAPDYG-ILKNYGKYVENTALLDTTDEIKEIVPLTRSFNYTSTPQGYANVFASQYSAEPLKVAVLTSNALEIYCYRTPDEVFESLIENPLPFIHSYGLSEACSTALYLACKFNKSEHIKSSALAFFSAGIPGVVEIKPKSSRESGSVPP----------------ISQNLFDKSG-------ECDGIVLSPRFYGSALLITRLFSQIWEERVFVFKRASKTEKMDAFG--------------------------ISITRPQVEYYLSSISVLADFFNIHRPSFVSFVPP----KGSN-------AITASDAESIAMNALILLINSIKDALSLINVFYED--IDAFKSLLNTLMGAGGVYDSKTREYFFDLKFHDLFTPNAKTKQLIKEILIEVVNANIASGTSADYIVNVLKERFGSFCHSADILCYRAGEHLEAAQKFEMIDSKISRNHLDTAIDLYERCAENIELCELRRVVDIMVKLNYQPKTVGFLLRFADKIDKGNQAQEYVSRGCNTAD--------PRKVFYDKRINVYTLIFEIVKSVDDYTSIEQSP----SIAN-ISIFSP-ASSLKKRVYSVIMNSNNRFFHYCFYDWLVANKRQDYLLRLDSQFVLPYLKERAEKS---LEISNLLWFYLFKEEHFLEAADVLYALASS-DFDLKLSERIECLARANGLCDSSTSFDQKPALVQLSENIHELFDIASIQDDLLNLVRNETRIDEDYRKQLTLKLNGRVLPLSDLFNDCADPLDYYEIKLRIFKVSQFKDEKVIQGEWNRLLDSMKNAPSPDVGSVGQESFLSSISNTLIRIGKTTRDTDVVFPVHFLMNKILESFID---------KSSAADGSVCSMFLLAGVSHLKLYYILSRIIENSEGNVELAKKEMVWLIKDWYQSDSDLRGSIAPEQIKKLEKYDPNTD-----PVQDYVKDRHHGLK------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38181-1", "uniprot_id": "NU170_YEAST", "id": "P38181-1", "name": "Nucleoporin NUP170", "aln": "MFQSFFHNNGPAAAGETFSDSRSYPLTNHQEVPRNGLNELASSATKAQQQPTHILNSYPITGSNPLMRASAMGATSGSINPNMSNMNEHIRVSGMGTSKPLDLAGKYIDHLQHKDSNTPVLDERSYYNSGVDYNFSREKNGLGAFTPFEKQDVFNIPDEILHEFSTSQTKTDMGIFPELNRCWITIDNKLILWNINNDNEYQVVDDMKHTIQKVALVRPKPNTFVPAVKHLLLISTTMELFMFAISLD-----------KATNELSVFNTHLSVPVQGIDVIDIVSHERSGRIFFAGQASGLNIWELHYSGSDDWFNSKCSKVCLTKSALLSLLPTNMLSQIPGVDFIQALFEDNSNGNGGFSQETITQLTIDQQRGIIYSLSSKSTIRAYVITEKSLEGPMSIEPAYISRIIGTTTARAAPILGPKYLKIVKISSVAPEENNNLFLVALTVGGVRLYFNGS--------------------------------MGRFNIEALRLESIKFPPSSVTPEVIQQELLHQQQEQAKRSFPFFSNLMSSEPVLLKFQKKSSVLLETTKASTIISPGIFFSAVIKSSQQTHQQEKKENSSVTGTTATAGSKTVKQQPVTLQHKLFVSVPDYG-ILKTHGKYVENATFLETAGPVQQIIPLSGLFNATTKPQGFANEFATQYTSETLRVAVLTSTSIEIYKYRTPDEIFEDLIDNPLPFVLNYGAAEACSTALFVTCKSNKSEKLRSNALTFLTMGIPGVVDIKPVYNRYSVSTVSSLLSKPTLSTATTNLQQSITGFSKPSPANKEDFDLDDVILSPRFYGIALLITRLLRDIWGRHVFMTFTDNRVTSHAFISSSDPITPSINNLKSDEISQNRNIISKVSISKDCIEYYLSSINILNEFFITYGDSISQISAPYVLANNSNGRVIDKTEEVANQAESIAINAMIKMVQSIKEGLSFLNVLYEESEVEGFDNQYLGFKDIISFVSLDVQKDLVKLDFKDLFAPNDKTKSLIREILLSIINRNITKGASIEYTATALQERCGSFCSASDILGFRAIEHLRRAKEIGLRNYDSLNYHLKNATALLEQIVDDLSIEKLKEAVSMMLSVNYYPKSIEFLLNIANSMDKGKLACQYVANGFLEND--------DRKQYYDKRILVYDLVFDTLIKVDELAEKKQSS----KTQNQISISNDDEVKLRQKSYEAALKYNDRLFHYHMYDWLVSQNREEKLLDIETPFILPYLMEKAGSS---LKISNILWVYYSRRSKFFESAEILYRLATS-NFDITLFERIEFLSRANGFCNSVSPLSQKQRIVQLASRIQDACEVAGIQGDILSLVYTDARIDSAIKDELIKTLDGKILSTSELFNDFAVPLSYHEIALFIFKIADFRDHEVIMAKWDELFQSLRMEFNNTGKKEDSMNFINLLSNVLIKIGKNVQDSEFIFPIFELFPIVCNFFYET------LPKEHIVSGSIVSIFITAGVSFNKMYYILKELIETSDSDNSVFNKEMTWLIHEWYKSDRKFRDIISYNDIIHLKEYKIDND-----PIEKYVKNSGNNLGICFYKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :: . : : . ..: . . :. .* : .. : : . : . . **:* :. .*:* *..: :*. :: : * :.. * * **:*... * *. **:::* .:: :: :: . :.:: : . :. *:**: * . ::*: *. . . *..:. *: ::. : ::*: : :. :.* :: :*:.* ::: : *. :. : : . : .: : * : : . * .:* ****:*. * * :::** . : : : . . : : . . ..: : . . * : : *: : : . : *: :. .. : : * : : * : . . . . .. .. : . * * . :: * :. * : .:*:: .:* . . . . : . *. *. ::.*: ::. : ::: ::: .. : . . :: : *:**. ..: :: .::* : . :. . *:: : * : :* * * ::: * : :. * . : : : *.. * . .: .* * * *. : : . : . ... . : . :: :: :*:**: . . ** : : .* . . . : ::** * :. . .:* :* ** . ::.* :*:* : ** . . .. : .:.: ::* :* .: : . : *: : :.*: . * *:. * * ::: : . * :: * :::. . : : . . . * : * . : . : .: . : : . : . * . : .*. * ", "identical_positions": 108, "similar_positions": 344, "identity": "6.87%" }, { "cls_id": "homologset.agr.RGD:621200", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62869-1", "uniprot_id": "ELOB_MOUSE", "id": "P62869-1", "name": "Elongin-B", "aln": "MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPEEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADDTFEALRIEPFSSPPELPDVMKPQDSGGSANEQAVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62870-1", "uniprot_id": "ELOB_RAT", "id": "P62870-1", "name": "Elongin-B", "aln": "MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPEEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADDTFEALRIEPFSSPPELPDVMKPQDSGGSANEQAVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15370-1", "uniprot_id": "ELOB_HUMAN", "id": "Q15370-1", "name": "Elongin-B", "aln": "MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADDTFEALCIEPFSSPPELPDVMKPQDSGSSANEQAVQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************************:************************************************ ********************.********", "identical_positions": 115, "similar_positions": 2, "identity": "97.46%" }, { "cls_id": "homologset.agr.RGD:621201", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62888-1", "uniprot_id": "RL30_HUMAN", "id": "P62888-1", "name": "Large ribosomal subunit protein eL30", "aln": "MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62889-1", "uniprot_id": "RL30_MOUSE", "id": "P62889-1", "name": "Large ribosomal subunit protein eL30", "aln": "MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M4H8-1", "uniprot_id": "A0ABK0M4H8_RAT", "id": "A0ABK0M4H8-1", "name": "Large ribosomal subunit protein eL30", "aln": "MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTAWKDFTEER", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VJ19-1", "uniprot_id": "Q9VJ19_DROME", "id": "Q9VJ19-1", "name": "Large ribosomal subunit protein eL30", "aln": "MVAVKKQKKALESTNARLALVMKSGKYCLGYKQTLKTLRQGKAKLVLIASNTPALRKSEIEYYAMLAKTEVQHYSGTNIELGTACGKYFRVCTLSITDPGDSDIIRSLETA----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P14120-1", "uniprot_id": "RL30_YEAST", "id": "P14120-1", "name": "Large ribosomal subunit protein eL30", "aln": "MAPVK----SQESINQKLALVIKSGKYTLGYKSTVKSLRQGKSKLIIIAANTPVLRKSELEYYAMLSKTKVYYFQGGNNELGTAVGKLFRVGVVSILEAGDSDILTTLA------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*...* : ** * :* **:***** ****.*:* :****:**:::* * *.*****:******:** * ::.* * ***** ** :** .::* :.*****: :: ", "identical_positions": 59, "similar_positions": 28, "identity": "48.76%" }, { "cls_id": "homologset.agr.RGD:621202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62900-1", "uniprot_id": "RL31_MOUSE", "id": "P62900-1", "name": "Large ribosomal subunit protein eL31", "aln": "MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62902-1", "uniprot_id": "RL31_RAT", "id": "P62902-1", "name": "Large ribosomal subunit protein eL31", "aln": "MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62899-1", "uniprot_id": "RL31_HUMAN", "id": "P62899-1", "name": "Large ribosomal subunit protein eL31", "aln": "MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V597-1", "uniprot_id": "RL31_DROME", "id": "Q9V597-1", "name": "Large ribosomal subunit protein eL31", "aln": "MTKTK--GEKIN-KSAINEVVTRECTIHLAKRVHNIGFKKRAPRAIKEIRKFAEREMGTTDVRIDTRLNKHIWSKGIRSTPFRIRVRLARRRNDDEDSPNKLYTYVTYVPVSTFKNLQTENVESSDD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C2H9-1", "uniprot_id": "RL31B_YEAST", "id": "P0C2H9-1", "name": "Large ribosomal subunit protein eL31B", "aln": "-------------MAGLKDVVTREYTINLHKRLHGVSFKKRAPRAVKEIKKFAKLHMGTEDVRLAPELNQAIWKRGVKGVEYRLRLRISRKRNEEEDAKNPLFSYVEPVLVASAKGLQTVVVEEDA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P0C2H8-1", "uniprot_id": "RL31A_YEAST", "id": "P0C2H8-1", "name": "Large ribosomal subunit protein eL31A", "aln": "-------------MAGLKDVVTREYTINLHKRLHGVSFKKRAPRAVKEIKKFAKLHMGTDDVRLAPELNQAIWKRGVKGVEYRLRLRISRKRNEEEDAKNPLFSYVEPVLVASAKGLQTVVVEEDA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:::***** **:: **:*.:.********:***:*** .*** ***: ..**: :* :*::.. :*:*:*::*:**::**: * *:: * * *:: *.*** *:.. ", "identical_positions": 52, "similar_positions": 41, "identity": "40.94%" }, { "cls_id": "homologset.agr.RGD:621203", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62911-1", "uniprot_id": "RL32_MOUSE", "id": "P62911-1", "name": "Large ribosomal subunit protein eL32", "aln": "MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNPNARLRSEENE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62912-1", "uniprot_id": "RL32_RAT", "id": "P62912-1", "name": "Large ribosomal subunit protein eL32", "aln": "MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNPNARLRSEENE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62910-1", "uniprot_id": "RL32_HUMAN", "id": "P62910-1", "name": "Large ribosomal subunit protein eL32", "aln": "MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNPNARLRSEENE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04359-1", "uniprot_id": "RL32_DROME", "id": "P04359-1", "name": "Large ribosomal subunit protein eL32", "aln": "-MTIRPAYRPKIVKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHNVRELEVLLMQNRVYCGEIAHGVSSKKRKEIVERAKQLSVRLTNPNGRLRSQENE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38061-1", "uniprot_id": "RL32_YEAST", "id": "P38061-1", "name": "Large ribosomal subunit protein eL32", "aln": "---MASLPHPKIVKKHTKKFKRHHSDRYHRVAENWRKQKGIDSVVRRRFRGNISQPKIGYGSNKKTKFLSPSGHKTFLVANVKDLETLTMHTKTYAAEIAHNISAKNRVVILARAKALGIKVTNPKGRLALEA--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :******:**:* **:**** :: .:*** :***. *****:*: *:*******:*:.: *:*.:.*** **::**.* * .: *..****.:*:*:* *: ** *.:::***:.** : ", "identical_positions": 64, "similar_positions": 42, "identity": "47.41%" }, { "cls_id": "homologset.agr.RGD:621204", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61927-1", "uniprot_id": "RL37_HUMAN", "id": "P61927-1", "name": "Large ribosomal subunit protein eL37", "aln": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D823-1", "uniprot_id": "RL37_MOUSE", "id": "Q9D823-1", "name": "Large ribosomal subunit protein eL37", "aln": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61928-1", "uniprot_id": "RL37_RAT", "id": "P61928-1", "name": "Large ribosomal subunit protein eL37", "aln": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VXX8-1", "uniprot_id": "RL371_DROME", "id": "Q9VXX8-1", "name": "Large ribosomal subunit protein eL37A", "aln": "MTKGTSSFGKRHNKTHTLCRRCGRSSYHIQKSTCAQCGYPAAKLRSYNWSVKAKRRKTTGTGRMQHLKVVRRRFRNGFREGTQAKPKKAVASK----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1U6-1", "uniprot_id": "RL372_DROME", "id": "Q9W1U6-1", "name": "Large ribosomal subunit protein L37-2", "aln": "MTKGTTSFGKRHNKTHTICRRCGNSSYHLQKSKCSQCGYPAAKTRSFNWSRKAKGRKAQGTGRMRYLKNLRRRFRNGLREGGAAKKKTN--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P51402-1", "uniprot_id": "RL37B_YEAST", "id": "P51402-1", "name": "Large ribosomal subunit protein eL37B", "aln": "MGKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPSAKTRSHNWAAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSAKATSA---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P49166-1", "uniprot_id": "RL37A_YEAST", "id": "P49166-1", "name": "Large ribosomal subunit protein eL37A", "aln": "MGKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPAAKTRSYNWGAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSASKASA---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ***.*****:**:**:*.*** ::*:**..*..****: : *..**. *** *:: *****::** : ***::*:: * . ", "identical_positions": 44, "similar_positions": 27, "identity": "45.36%" }, { "cls_id": "homologset.agr.RGD:621205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62513-1", "uniprot_id": "ZN260_MOUSE", "id": "Q62513-1", "name": "Zinc finger protein 260", "aln": "-----------------------------------------------MLESLQPESHLL-HDEPDPGESV--------------YECNECKETFSLEQN--------FVEHKKTHSGE---------------------------KSPECTGCGEESSQASSLTLHLRSRPRRESYKCGECGKAFSQRGNFLSHQKQHTEERPS---ESKKTPVPMTTTVRNQRN-TGNKPYACKECGKAFNGKSYLKEHEKIHTGEKPFECSQCGRAFSQKQYLIKHQNIHSGKKPFKCNECGKAFSQKENLIIHQRIHTGEKPYECKGCGKAFIQKSSLIRHQRSHTGEKPYTCKECGKAFSGKSNLTEHEKIHIGEKPYKCNECGTIFRQKQYLIKHHNIHTGEKPYECNKCGKAFSRITSLIVHVRIHTGDKPYECKICGKAFCQSSSLTVHMRSHTGEKPYGCNECGKAFSQFSTLALHMRIHTGEKPYQCSECGKAFSQKSHHIRHQRIHIH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62981-1", "uniprot_id": "ZN260_RAT", "id": "Q62981-1", "name": "Zinc finger protein 260", "aln": "-----------------------------------------------MLESLQPESELL-HDEPDPGEKV--------------YECDECRKTFSLEQH--------FVEHKKTHGGE---------------------------KSPECTGCGEEFSKASSLTRHLRSRSRRESYKCGNCGRTFSQRGNFLSHQKQHAEERPS---ESKKTPVPMTTIVRNQRN-AGNKPYACKECGKAFNGKSYLKEHEKIHTGEKPFECNQCGRAFSQKQYLIKHQNVHSGKKPFKCNECGKAFSQKENLIIHQRIHTGEKPYECKGCGKAFIQKSSLIRHQRSHTGEKPYTCKECGKAFSGKSNLTEHEKIHIGEKPYKCNECGTIFRQKQYLIKHHNIHTGEKPYECNKCGKAFSRITSLIVHVRIHTGDKPYECKVCGKAFCQSSSLTVHMRSHTGEKPYGCNECGKAFSQFSTLALHMRIHTGEKPYQCSECGKAFSQKSHHIRHQRIHIH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3ZCT1-1", "uniprot_id": "ZN260_HUMAN", "id": "Q3ZCT1-1", "name": "Zinc finger protein 260", "aln": "--------------------------------------------MIGMLESLQHESDLLQHDQIHTGEKP--------------YECNECRKTFSLKQN--------LVEHKKMHTGE---------------------------KSHECTECGKVCSRVSSLTLHLRSHTGKKAYKCNKCGKAFSQKENFLSHQKHHTGEKPY---ECEKVSIQMPTIIRHQKNHTGTKPYACKECGKAFNGKAYLTEHEKIHTGEKPFECNQCGRAFSQKQYLIKHQNIHTGKKPFKCSECGKAFSQKENLIIHQRIHTGEKPYECKGCGKAFIQKSSLIRHQRSHTGEKPYTCKECGKAFSGKSNLTEHEKIHIGEKPYKCNECGTIFRQKQYLIKHHNIHTGEKPYECNKCGKAFSRITSLIVHVRIHTGDKPYECKVCGKAFCQSSSLTVHMRSHTGEKPYGCNECGKAFSQFSTLALHMRIHTGEKPYQCSECGKAFSQKSHHIRHQRIHTH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TMX9-1", "uniprot_id": "A0AB32TMX9_DANRE", "id": "A0AB32TMX9-1", "name": "", "aln": "----------------------------MAFIKEESEDVEIEETFTVKQEDLQEQTGSVRTQRKTPAEATDLHTVIKMAFIKEESEDVEIEETFTVKQEDLQEQTDLFKEYERSKEEEHHVKIEDKTHLE-----TDDILKMRDKRCFTCNQCGKSLANKSKLKIHMRVHNREKLFTCTQCGKNFNQSSHLNQHMRIHTGEKPFTCTQCGKSFSYSANLNQHMRIHTGEKPFTCTQCGKSFSNSANLNQHMRIHTGEKPFTCTQCGKSFSQSSYLNQHMRIHTGEKPFTCSQCGKSFSQSPYLNQHMRIHTGEKPFTCSQCGKSFSQSSSLYLHMRIHTGEKPFTCTQCGKSFSKSSNLNIHMRNHTGEKPFTCLQCGKSFSQSTSLNLHMRIHTGEKPFTCTQCGKSFSQSSNPNIHMRNHIGEKPFTCTQCEKSFSQSTSLNRQMMIHTGEKEFMCLKCENTFITAAELKRHQRVHTGEKPYKCSQCSKRFTRSGTLKTHERIHTGEKL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VG72-1", "uniprot_id": "Q9VG72_DROME", "id": "Q9VG72-1", "name": "Zinc finger protein 865", "aln": "MDLANVDQRPVKDEPPQEDTFEEELIFISNSDFEELESEIKIENFCSYGKDLEPVKGVPSKLKTCKSKIAKKRP---LRKQTDTFKCTQCQKTFTRKEN--------LESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLKHEKRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTHA-ERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLRRTLCGTKSD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*: . . .: : : .:**: ::. : .: : : * : *. *.: :. *.*. *:: : .. :.* :*. * : :: * : *: *:* .. * . .: : :*: *..*.*:*. : * :* *: *:.* *.** ::* *.. * * .:*:*:.**.* .*.::*::. * * *:*::* *. *. :* * * * ** *: :.* :*.*:* .*:* * : * **:*:.* .* . * * * * *** *. *.* *. :. :*:: * *.: : * * *:: *::* :: **** : * .* : * : * * *******:**.*.. :::.. * * ", "identical_positions": 108, "similar_positions": 129, "identity": "21.05%" }, { "cls_id": "homologset.agr.RGD:621206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97832-1", "uniprot_id": "HAND1_RAT", "id": "P97832-1", "name": "Heart- and neural crest derivatives-expressed protein 1", "aln": "MNLVGSYAHHHHHHHSHPPHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPTTAVAAAAYGPDARPSQSPGRLEALGGRLPRRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQAGDPEAFKAELKKTDGGRESKRKRESPQQHEGLPPALGPSEKRIKGRTGWPQQVWALELNQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64279-1", "uniprot_id": "HAND1_MOUSE", "id": "Q64279-1", "name": "Heart- and neural crest derivatives-expressed protein 1", "aln": "MNLVGSYAHHHHHHHSHPPHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPTTAVAAAAYGPDARPSQSPGRLEALGSRLPKRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQAGDPEAFKAELKKTDGGRESKRKRELPQQPESFPPASGPGEKRIKGRTGWPQQVWALELNQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O96004-1", "uniprot_id": "HAND1_HUMAN", "id": "O96004-1", "name": "Heart- and neural crest derivatives-expressed protein 1", "aln": "MNLVGSYAHHHHHHHPHPAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPAAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKDAQSGDPEAFKAELKKADGGRESKRKRE-LQQHEGFPPALGPVEKRIKGRTGWPQQVWALELNQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL05-1", "uniprot_id": "Q9VL05_DROME", "id": "Q9VL05-1", "name": "", "aln": "---------------------MFKN----SVALTCEYSTMYYN----SIYNTSNMFDMKHS--ESQVQQQIYN-----TSHLGYVPTSNTRIVKKRNTANKKERRRTQSINNAFSYLREKIPNVPTDTKLSKIKTLKLAILYINYLVNVLDGDLDPKG--GFRAELKPVSRKICSEKKHCLKSEIQNVPLS-------TKGRTGWPQDVWASELIPEHN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::: . * *. . *:: * ::: * . : . *. . * : : . *: :::.:. *******:***.**: *** *****:**********:** ** **::** * :. . .*:**** .. *::*: .: :..* : ********:*** ** ", "identical_positions": 69, "similar_positions": 50, "identity": "31.51%" }, { "cls_id": "homologset.agr.RGD:621207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61295-1", "uniprot_id": "HAND2_RAT", "id": "P61295-1", "name": "Heart- and neural crest derivatives-expressed protein 2", "aln": "MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKD-DQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61039-1", "uniprot_id": "HAND2_MOUSE", "id": "Q61039-1", "name": "Heart- and neural crest derivatives-expressed protein 2", "aln": "MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKD-DQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61296-1", "uniprot_id": "HAND2_HUMAN", "id": "P61296-1", "name": "Heart- and neural crest derivatives-expressed protein 2", "aln": "MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKD-DQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57102-1", "uniprot_id": "HAND2_DANRE", "id": "P57102-1", "name": "Heart- and neural crest derivatives-expressed protein 2", "aln": "MSLVGGFPHHPVMHHDGYSFA------AAAAASRC-HEEPPYFHGWLISHPEMSPPDYTMAPSYSPEYSTGAPGLDHSHYGGVP-GAGAVGMG-PRTVKRRPTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDILDKD-EQNGETEAFKAEFKKTDAKEERRKKEMNDVLKSSGSSNDKKTKGRTGWPQHVWALELKQ---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL05-1", "uniprot_id": "Q9VL05_DROME", "id": "Q9VL05-1", "name": "", "aln": "------------MFKN-------------SVALTC--EYSTMYYNSIYNTSNMFDMKHSESQVQQQIYNT-------SHLGYVP-------TSNTRIVKKRNTANKKERRRTQSINNAFSYLREKIPNVPTDTKLSKIKTLKLAILYINYLVNVLDGDLDPKG---GFRAELKPVSRKICSEKK---HCLKSEIQNVPLSTKGRTGWPQDVWASELIPEHN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:: :.* * * . ::. : . .:* .:: : . * : ** * ** . .* **:* ***:**********.**: *** *****:**********:** ** **:::* * : :* .*:**:* .. * .** . *** .. .*********.*** ** ", "identical_positions": 80, "similar_positions": 44, "identity": "36.2%" }, { "cls_id": "homologset.agr.RGD:621208", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTY2-1", "uniprot_id": "S4A7_MOUSE", "id": "Q8BTY2-1", "name": "Sodium bicarbonate cotransporter 3", "aln": "-----MEADGAGEQMRPLLTRGPDEEAVVDLGKTSSTVNTKFEKEELESHRA--VYVGVHVPFSK---ESRRRHKHRG-----------------HKHHHRRRKDKDSDKEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDDSIRENVREALLKRHHHQNEKRFTSRIPLVRSFADIG--------------------------------------------------------------------------------------------------------------------------------------------------ILASPQSAPGNLDNSKSGEMKGNGSGGSRENSTVDFSK---------------------VDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLSGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFPNGSAAMSVGPPKEDDHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCRDYHLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFHLGEIYAFNMHNNLDELTSYTCVCAEPSNPSNETLELWKRKNITAYSVSWGNLTVSECKTFHGMFVGSACGPHGPYVPDVLFWCVVLFFTTFFLSSFLKQFKTKGYFPTKVRSTISDFAVFLTIVIMVAIDYLVG----IPSPKLHVPEKFEPTDPSRGWIISPLGD--NPWWTLLIAAVPALLCTILIFMDQQITAVIINRKEHKLK--------------------------------------------------------------------------------------FIPMPVLYGVFLYMGVSSLKGIQFFDRIKLFGMPAKHQPDLIYLRYVPLWKVHVFTVVQLTCLVLLWVIK-ASAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQDD--------------EDTVHLPFER------GSLLQIPVKTLKYSIDPSVVN--------------------ISDEMAKTAQWKALSMNTENAKVTRPNTSPEKPVSVTINFEDEPSK-KYMDAETSL------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R1N3-1", "uniprot_id": "S4A7_RAT", "id": "Q9R1N3-1", "name": "Sodium bicarbonate cotransporter 3", "aln": "-----MEADGAGEQMRPLLTRGPDEEAVVDLGKTSSTVNTKFEKEELESHRA--VYVGVHVPFSK---ESRRRHRHRG-----------------HKHHHRRRKDKDSDKEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDDSIRENVREALLKRHHHQNEKRFTSRIPLVRSFADIGKKHSDPHLLERNGEGLSASRHSLRTGLSASNLSLRGESPLSLLLSHLLPSSRAGTPAGSRCTTPVPTPQNSPPSSPSLSRLTSRSSQQTQPQAPEVLVSPDRDDIPRVVIHPPEEDIEALK-GQEQKNEENTDFTP---------GILASPQSAPGNLDSSKSGEVKGNGSGGSRENSTVDFSK---------------------VDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLSGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPAFPNGSAPVSADPPKEADHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCRDYHLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFHLGEIYAFNMHNNLDALTSYTCVCAEPSNPSNETVELWERKNVTAASISWANLTVSECKTFHGMFVGSACGPHGPYVPDVLFWCVVLFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVAIDYLVG----IPSPKLHVPEKFEPTDPSRGWIISPLGD--NPWWTLLIAAVPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMI--FILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQFFDRIKLFGMPAKHQPDLIYLRYVPLWKVHVFTVVQLTCLVLLWVIK-ASAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQGD--------------GDTVHLPFER------GSLLQIPVKTLKY--------------------------------------------------------SPEKPVSVTINFEDEPSK-KYMDAETSL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6M7-1", "uniprot_id": "S4A7_HUMAN", "id": "Q9Y6M7-1", "name": "Sodium bicarbonate cotransporter 3", "aln": "-----MERFRLEKKLP-----GPDEEAVVDLGKTSSTVNTKFEKEELESHRA--VYIGVHVPFSK---ESRRRHRHRG-----------------HKHHHRRRKDKESDKEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDESIRENVREALLKRHHHQNEKRFTSRIPLVRSFADIGKKHSDPHLLERNGEGLSASRHSLRTGLSASNLSLRGESPLSLLLGHLLPSSRAGTPAGSRCTTPVPTPQNSPPSSPSISRLTSRSSQESQRQAPELLVSPASDDIPTVVIHPPEEDLEAALKGEEQKNEENVDLTP---------GILASPQSAPGNLDNSKSGEIKGNGSGGSRENSTVDFSK---------------------VDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFHNGSTPTLGETPKEAAHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFDLGETYAFNMHNNLDKLTSYSCVCTEPPNPSNETLAQWKKDNITAHNISWRNLTVSECKKLRGVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVTIDYLVG----VPSPKLHVPEKFEPTHPERGWIISPLGD--NPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMI--FILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTVIQLTCLVLLWVIK-VSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQDD--------------DDTVHLPFEG------GSLLQIPVKALKY--------------------------------------------------------SPDKPVSVKISFEDEPRK-KYVDAETSL------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PN97-1", "uniprot_id": "A0A8M9PN97_DANRE", "id": "A0A8M9PN97-1", "name": "Anion exchange protein", "aln": "MQDFWGDVAHMRTTIGATASSGNDDEAVVDQGKTSSNIHTNFEKEELESHRA--VYVGVHVPLGR---QSRRRHRHRG-----------------HKHHRKR-KDRCSEREDGRDSPTYDTPSQRVQFILGTEDDDEEHIPHDLFTELDELCFRDGLTCEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVMLDMRANSIEEIADMVLDNMVASEQLDESVREKVRDAVLKRHHHQNEKKLSNRIPLVRSFADIGKKHSDPHLLERNGEGLSTSRLSLLRRTSSTSTPPSSRRP-SRESRYSRSSIILNQLLSSANSTPSTTPQNSPPTAHRASP-SLRPPGPSQQGPELLVARGDRDDIPEVVVFPPEEDVGDPLPAFYAVQDEKVVHDPTRLLPLPQSGLLASPQSAPGILENSKSSESRINGTGGSRENSTVDFSRDSQSPFHCSCGSLGVGTKRPAVDMNFMKKIPPGAEASNVLVGEVDFLERPIIAFIRLSPAVLLTGLTEVPVPTRFLFLLLGPFGKGAQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPTIRIEPPKSVPSQEKRKMPSMPNGSTPQS-DVIKQEAHHAGPELQRTGRIFGGLVLDLKRKAPFYWSDVRDAFSLQCLASILFLYCACMSPVITFGGLLGEATKNNISAIESLFGASLTGVAFSLFAGQPLTILGSTGPVLVFEKILFKFCSDYGLSYLPLRTSIGLWTAFLCLLLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFQLGKMYPFNMHDDLNNLTFYTCQCSPPSNTTQKMEQSWNQSGFTYDTINWTELNVQDCRDLHGEFVGPACGHNGPYIPDVLFWSVILFFTTFFLSSFLKQFKTKRYFPTKVRSSISDFAVFLTIMIMVLVDYLVG----IPSPKLHVPDRFEPTSKNRGWLISPLGD--NPTWTLFAAAIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVAVMLGVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMI--FVLMGLSVFMTSILKFIPMPVLYGVFLYMGVSSLRGIQFFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTLVQLTCLVLLWVIK-VSAAAVVFPMMVLALVFVRKLLDFCFTKRELSWLDDLMPESKKKKEDDKKKKAKEEAQRMMEA---------------EEEIEIPFDG------GDQLEIPEKTIQISTDPSVVN--------------------ISDEMAKTAAWKG-GNSSESATLLKASASEEKTACIKIRVEDEDEEDKRVDTETSL------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPI3-1", "uniprot_id": "Q8IPI3_DROME", "id": "Q8IPI3-1", "name": "Anion exchange protein", "aln": "----MAEKNEYIELPWTMNSSSGDDEAPKDPRTGGEDFTQQFTENDFEGHRAHTVYVGVHVPGGRRHSQRRRKHHHSGPGGGGGGGGGGGSIGGSGSVGGGAGKDNVSEKQQEVERP-VTPPAQRVQFILGEDVDDGTHVSHPLFSEMGMLVK-EGDEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRHQHEYAKKTRLPIIRSLADMRNHSSS------------------------------------------------------------------------------------------------------------------------KKKKSNSKHSR----------PAQNLSSITEDMVKSPSNQSMAR-PGSGTELSEQQHKG----------------------NTHFMRKIPPGAEASNILVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRP--PELPKEEVDEEEEEARLREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQG-------IYDCVCTPPIGSN-------------ASVIDYAKYNWDSCESYNGTLVGGDCG--TPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSLG----VPTQKLEVPNELKPTLSTRGWLIPPFVEK-NPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILI--FLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDLHKLDAEDNHHQHPPGSGAGANYNADKSGPTTIHIPLSGNKTGTKGPTVNIPQEAVNRTAVWQQINKDGNGISEQLIIPVTLKVRQINGNHAPSSATLSPRLSPMHEADEYSEAPTNSPAHPAGNQQQQQQQINNCKEAAKLDGSCSNNSQISPANITPV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53838-1", "uniprot_id": "BOR1_YEAST", "id": "P53838-1", "name": "Boron transporter 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNESTRVTVSRGCTASDECAQALERTNDELDRESSVS------------------------------------ESRSDEESHEKLSRRRFPTLGIGIWLDLKDRIPYYKSDWVDAFNYRVIPSIVDTYFNNLLPAIAFAQDMFDRTDNSYGVNEVLLSSAMAGIVFGVLGGQPLCIVGVTGPISIFNYTVYEIIKPLNTSYFGFMFWICMWSMIFHLVLAFTNAVCLLQYVTTFPCDIFGLFINVVYIQKGIQILTRQ----------------------------------------------------FSAKSGEKSVQDG--------------FASVVVALVMTAFGLFFKLFHYYPLFSHRIRTFISDYSTALSVLFWSSFTHFGGYLHDVKFKKLPITKAFFPTSKVNRPQNTWLAYEPIPVKDVFIALPFGIFLTILFYFDHNVSSLMAQRHQYKLKKPSSFHYDFALLGLTTCISGVLGIPAPNGLIPQAPLHTETLLVRDS------NQKVISCVEQRFTNTFQGLMILGTMTRPLLVCLGEIPQAVLSGLFFIMGINGLMTNSIIQRLVFLFSDPNRRDNTSPLMKVSKKSMLIFLSFSLTGFAGEFAIT-NTIAAIGFPLVLLLSVLVSFSFAYIFPTEELKILDTNVAQKFTIKNLLLENIRDAKFCDKHED--------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : . . : . . *. :: ** : :. .: : * : *: *:* : *:: ** **:. : :.* : * : * *:*. : : * .. * *... : *: :..:.**** *:* ***: :*: :::: .*: : * :* : ::*. :* .*: *:* *. : *. :* .::* :.:: : . .. * : .*:: :. .:* *: *. :* ***::. :::. . : * : ** :.. : ** . . : * : * .:: ***:::*::::::: :*:: *** ** .** *:*: **: .* .:::*: :: .: : : * *. : :* ..*: : : *. : ::: **:::: : : : *. .**. ** :.: . : . : . ", "identical_positions": 89, "similar_positions": 174, "identity": "6.45%" }, { "cls_id": "homologset.agr.RGD:621209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47868-1", "uniprot_id": "SCG3_RAT", "id": "P47868-1", "name": "Secretogranin-3", "aln": "MGFLWTGSWILVLVLNSGPIQAFPKPEGSQDKSLHNRELSAERPLNEQIAEAEADKIKKTYPSESKPSESNFSSVDN-LNLLKAITEKETVEKAKQSIRSSPFDNRLNVDDADSTKNRKLTDEYDSTKSGLDRKVQDDPDGLHQLDGTPLTAEDIVHKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHTLEDEVAEALQKLISKEANN---------YEEAPEKPTSRTENQDGKIPEKVTPVAATQDGFTNREN-------DDTVSN--TLTLSNGLERRTNPHRDDDFEELQYFPNFYALLTSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNTTDSKSKLFPAPPEKSHEETDSTKEEAAKMEKEYGSLKDSTKDDNSNLGGKTDEAKGKTEAYLEAIRKNIEWLKKHNKKGNKEDYDLSKMRDFINQQADAYVEKGILDKEEANAIKRIYSSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47867-1", "uniprot_id": "SCG3_MOUSE", "id": "P47867-1", "name": "Secretogranin-3", "aln": "MGFLWTGSWILVLVLNSGPIQAFPKPEGSQDKSLHNRELSAERPLNEQIAEAEADKIKKAFPSESKPSESNYSSVDN-LNLLRAITEKETVEKERQSIRSPPFDNQLNVEDADSTKNRKLIDEYDSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVHKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHTLEDEVAEALQKLISKEANN---------YEETLDKPTSRTENQDGKIPEKVTPVAAVQDGFTNREN-------DETVSN--TLTLSNGLERRTNPHREDDFEELQYFPNFYALLTSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNTTDSKSKLFPAPPEKSQEETDSTKEEAAKMEKEYGSLKDSTKDDNSNLGGKTDEATGKTEAYLEAIRKNIEWLKKHNKKGNKEDYDLSKMRDFINQQADAYVEKGILDKEEANAIKRIYSSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXD2-1", "uniprot_id": "SCG3_HUMAN", "id": "Q8WXD2-1", "name": "Secretogranin-3", "aln": "MGFLGTGTWILVLVL---PIQAFPKPGGSQDKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPGQSNYSFVDN-LNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDYDSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANN---------YEEDPNKPTSWTENQAGKIPEKVTPMAAIQDGLAKGEN-------DETVSN--TLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDNISKLFPAPSEKSHEETDSTKEEAAKMEKEYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKEDYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KQQ9-1", "uniprot_id": "SCG3_DANRE", "id": "A3KQQ9-1", "name": "Secretogranin-3", "aln": "MASKRLG-FVVVLALVCQHINAFPTPAGPDDK--YNRELTEEKPLEQQIAEADS--IRKTESKPTPPAEEETNSEDDDITFLKALAEKSKESNNETPISDS-ANERLGADDTDSTKNRRLADDYDSTKNGMDYKYQDDPESFRQLDGTPLTAQDIVQKIANKIYEEDDRGVFDRIVSKLLKLGLITDSQAETLEYEVAEALQDLITKNAKDNMIGDRSVDYPVSAAKDTQDEEDRPSPRFDEEDEVENEGGDDANGDEPQEEESRDDTVRSDDSWDAVSDGNDRNELNPEDGLQDLQFFPNFYRLLKSLDSEQDKEERETLITIMKTLIDFVKMMVKYGTITPEEGVTYLENLDAMIALQTKNKLGKSLVPLS---ITPPTGKAADDDDNTKTEAAKMQKEYESLKDSTKDVQT--AAEISHP-GKSESYLEAIRKNIEWLKKHNKEGNKEDYDLSKLRDFMDQQVDSYIDKGILEKDEGDVIKRIYGSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * :::**.* *:***.* *.:** :****: *:**::*****: *:*: . . *.:.: . *: :.:*:*::**.. .: . .* .. :::*..:*.******:* *:*****.*:* * ****:.::*********:***:*** :****:**.***:******:*****:***.*** ****.**.**:*:*:: * * *. *:: . :: : .. :: :: *:** . : .. : *.: :*.:::**:***** **.*:***:: :*:***********************:*****:****** ********* *. . :..*. *: :: *.** *****:*** ******** :: ..: ... **:*:***************:*:**********:***:::*.*:*::****:*:*.:.*****.**", "identical_positions": 243, "similar_positions": 141, "identity": "49.59%" }, { "cls_id": "homologset.agr.RGD:621210", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62947-1", "uniprot_id": "RS32_MOUSE", "id": "P62947-1", "name": "Small ribosomal subunit protein eS32", "aln": "MRAKWRKKRMRRLKRKRRKMRQRSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62948-1", "uniprot_id": "RS32_RAT", "id": "P62948-1", "name": "Small ribosomal subunit protein eS32", "aln": "MRAKWRKKRMRRLKRKRRKMRQRSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62945-1", "uniprot_id": "RS32_HUMAN", "id": "P62945-1", "name": "Small ribosomal subunit protein eS32", "aln": "MRAKWRKKRMRRLKRKRRKMRQRSK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************************", "identical_positions": 25, "similar_positions": 0, "identity": "100.0%" }, { "cls_id": "homologset.agr.RGD:621211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QY10-1", "uniprot_id": "FGFP1_RAT", "id": "Q9QY10-1", "name": "Fibroblast growth factor-binding protein 1", "aln": "-------MRIHGLILLSFLLLAAQVLSEKVRKTAKNVPDSTTEEDMS---PSLGKARNKQRSRTSKSMTHGRFVTKDQATCRWAVTEEELGINLKVQCTRADQE-----FSCVFAGDPTGCLKYDKDQ-TYWKQVARTLRKQKNICENSKSVLKTRVCRKKFPESNLKVVNP--------RKEKAEVSPREHNKVQEAVSMEPNKVKVDITTSPAAT--VAVKDSECLE--DPDVLTQRKTALEFCGESWSSFCTFFLNMLQATSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70514-1", "uniprot_id": "FGFP1_MOUSE", "id": "O70514-1", "name": "Fibroblast growth factor-binding protein 1", "aln": "-------MRLHSLILLSFLLLATQAFSEKVRKRAKNAPHSTAEEGVEGSAPSLGKAQNKQRSRTSKSLTHGKFVTKDQATCRWAVTEEEQGISLKVQCTQADQE-----FSCVFAGDPTDCLKHDKDQ-IYWKQVARTLRKQKNICRNAKSVLKTRVCRKRFPESNLKLVNPNARGNTKPRKEKAEVSAREHNKVQEAVSTEPNRVKEDITLNPAATQTMAIRDPECLE--DPDVLNQRKTALEFCGESWSSICTFFLNMLQATSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14512-1", "uniprot_id": "FGFP1_HUMAN", "id": "Q14512-1", "name": "Fibroblast growth factor-binding protein 1", "aln": "-------MKICSLTLLSFLLLAAQVLLVEGKKKVKNGLHSKVVSEQK---DTLGNTQIKQKSRPGN---KGKFVTKDQANCRWAATEQEEGISLKVECTQLDHE-----FSCVFAGNPTSCLKLKDER-VYWKQVARNLRSQKDICRYSKTAVKTRVCRKDFPESSLKLVSSTLFGNTKPRKEKTEMSPREHIKGKETTPS-----------SLAVTQTMATKAPECVE--DPDMANQRKTALEFCGETWSSLCTFFLSIVQDTSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PPG4-1", "uniprot_id": "A0A8M9PPG4_DANRE", "id": "A0A8M9PPG4-1", "name": "", "aln": "MLFINTAMRGWSLLFLLSLLFLLHSFSEAKKK-SRQPSEAVAGSDITPINPSLG---------------SGQLSTKDGHRCTWETLERGANIVLQVSCSVAGEDGLKPPYTCQFAGKPQECSAYNDQSSQYWKQVVSKLKRRENACEGEK-VLKTRLCKKASSASHMKLTERSGVETTTHMSEGTQDSKRKTDVPARKEKDVQKE-------KKEEEEEMKKDEDDGVEGIVNDEFSDMEPAVGYCRESWHSLCRFFGKFFDG---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q0I5-1", "uniprot_id": "A0A8M9Q0I5_DANRE", "id": "A0A8M9Q0I5-1", "name": "", "aln": "-----MSLRGIFAFLLFLACVSQLILTAECTRGARRKGRRQERRGDNNINVMKG----------------KFIINDKTQQCTWVARGEDK-YTMNVTCKPGSGDG----FTCKYTAKPATCAEYSSNPKGYWKQIARSLQKQKKLCVDPRALIRAGMCKRAPLDAHFKLTEAS-----QKKPPSTEKTPTATNTPP------------------------PDTEQGCTER-----IDHRELAREKCGDSWASLCAFLFTVIQSGDC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* . : : :. * : ... * * . . ::* *. . : ::* ::..* * ..: ****:. .*: ::. * : ::: :*:: : :*:.. :: : * . : * * ::* *:* *: ...: ", "identical_positions": 24, "similar_positions": 60, "identity": "9.02%" }, { "cls_id": "homologset.agr.RGD:621213", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08662-1", "uniprot_id": "PI4KA_RAT", "id": "O08662-1", "name": "Phosphatidylinositol 4-kinase alpha", "aln": "MAAAGARG---------TGGSGSSSGSSTSRGFYFNTVLSLARSLAVQRPASLEKVQKLLCMCP-VDFHGIFQLDERRRDAVIALGI---FLIESDLQHKDCIVPYLLRLLRGLPKVYWVEES-TARKGRGNLPVAESFSFCLVTLLSDVACRDPSLRDEILEALLQVLHVLLGMCQALEIQEKE----YLCKYAIPCLIGISRSFGRYSNSEESLLSKLFP-KVPPHSLRIPEELEGVRRRSFNDFRSILPSN--LLTVCQEGTLKRKTSSVSSIS-QVSPERGMPPPSSPGGSAFHYFEAS-CLPDGTTLEPEYYFSTISSSFS-----VSPLFNGIT--YKEFYIPLEMLRELLNLVKKIVEEPVLKSLDAAVARVMEANPSADLYYTTFSDPVYLTMFKMLRDTLYYMKDLPTSFVKEIHDFVLEQFNMSQGELQKILHDADRIHSEMS------PLKLRCQANAACVDLMVWAVKDE--------------------QGAENLCIKLSEKLQSKTSSKVIIAHLPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVIPSPVLVKLYKYHSQYHTVAGSDIKIS---VTNEHSES-TLNVLPGKKNQP----------SMYEQLRDIAIDNICRCLKAGLTVDPVIVEAFLASLSNRLYISQESDKD-------AHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIIDQLGCLVITG-NQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAANIQEEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLTRRLPPIKEAKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSKEPLRS-VLQYNSAMKNDTVTPAELNELRSTIINLLDPPPE-VSALINKLDFAMSTYLLSVYRLEYMRVLRSTDPDRFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMAEKAKTKENEEELERHAQFLLVNFNHIHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLS-ADIHKDQP--YYDIPDAPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNKQNTTLGVTQLTERPACVKKDYSNFMASLNLRNRYAGEVHGMIRFSGATGQMSDLNKMMVQDLITALDHSHPQHYTQAMFKLTAMLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKNGVEVPFMREMAGAWHMTVEQKFGLFSAETKEADP----------LAASEASQPRPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLHIGGARGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPT-QGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPP-------------------------------DNQD-------------TRSNLDITVGSRQQ-ATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQ-LHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELEL--DQAGENSVANWRSKYISLSEKQWKDNVNLAWTISPYLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAAAKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLEQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGD--ERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLQCRSDTEDECRRQEADGKKICWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRG-QTIKLLKHRFSPNMTEREAANFIMKIIQNCFLSNRSRTYDMIQYYQNDIPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q3L2-1", "uniprot_id": "PI4KA_MOUSE", "id": "E9Q3L2-1", "name": "Phosphatidylinositol 4-kinase alpha", "aln": "MAAAGARGGGGGGGGGGGGGSGSSSGSSTSRGFYFNTVLSLARSLAVQRPASLEKVQKLLCMCP-VDFHGIFQLDERRRDAVIALGI---FLIESDLQHKDCVVPYLLRLLRGLPKVYWVEES-TARKGRGNLPVAESFSFCLVTLLSDVACRDPSLRDEILEAILQVLHVLLGMCQALEIQEKE----YLCKYAIPCLIGISRSFGRYSNSEESLLSKLFP-KVSPHSLRIPEELEGVRRRSFNDFRSILPSN--LLTVCQEGTLKRKTSSVSSIS-QVSPERGIPPPSSPGGSAFHYFEAS-CLPDGTALEPEYYFSTISSSFS-----ISPLFNGIT--YKEFCIPLEMLRELLNLVKKIVEEPVLKSLDAIVAGVMEANPSADLYYTTFSDPLYLTMFKMLRDTLYYMKDLPTSFVKEIHDFVLEQFNMSQGELQKILHDADRIHSEMS------PLKLRCQANAACVDLMVWAVKDE--------------------QGAENLCIKLSEKLQSKTSSKVIIAHLPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVIPSPVLVKLYKYHSQYHTVAGSDIKIS---VTNEHSES-TLNVLPGKKNQP----------SMYEQLRDIAIDNICRCLKAGLTVDPVIVEAFLASLSNRLYISQESDKD-------AHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIIDQLGCLVITG-NQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAANIQEEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLTRRLPPIKEAKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSKEPLRS-VLQYNSAMKNDTVTPAELSELRSTIINLLDPPPE-VSALINKLDFAMSTYLLSVYRLEYMRVLRSTDPDRFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMAEKAKTKENEEELERHAQFLLVNFNHIHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLS-ADIHKDQP--YYDIPDAPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNKQNTTLGATQLTERPACVKKDYSNFMASLNLRNRYAGEVHGMIRFSGATGQMSDLNKMMVQDLITALDHSHPQHYTQAMFKLTAMLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKNGVEVPFMREMAGAWHMTVEQKFGLFSVETKEADP----------LAASEASQPRPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLNIGGARGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPT-QGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPP-------------------------------DNQD-------------TRSNLDITVGSRQQ-ATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQ-LHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELEL--DQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAAAKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLEQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGD--ERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLQCRSDAEDECFSQEADGKKICWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRG-QTIKLLKHRFSPNMTEREAANFIMKVIQNCFLSNRSRTYDMIQYYQNDIPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42356-1", "uniprot_id": "PI4KA_HUMAN", "id": "P42356-1", "name": "Phosphatidylinositol 4-kinase alpha", "aln": "MAAAPARGGGGGG---GGGGGCSGSGSSASRGFYFNTVLSLARSLAVQRPASLEKVQKLLCMCP-VDFHGIFQLDERRRDAVIALGI---FLIESDLQHKDCVVPYLLRLLKGLPKVYWVEES-TARKGRGALPVAESFSFCLVTLLSDVAYRDPSLRDEILEVLLQVLHVLLGMCQALEIQDKE----YLCKYAIPCLIGISRAFGRYSNMEESLLSKLFP-KIPPHSLRVLEELEGVRRRSFNDFRSILPSN--LLTVCQEGTLKRKTSSVSSIS-QVSPERGMPPPSSPGGSAFHYFEAS-CLPDGTALEPEYYFSTISSSFS-----VSPLFNGVT--YKEFNIPLEMLRELLNLVKKIVEEAVLKSLDAIVASVMEANPSADLYYTSFSDPLYLTMFKMLRDTLYYMKDLPTSFVKEIHDFVLEQFNTSQGELQKILHDADRIHNELS------PLKLRCQANAACVDLMVWAVKDE--------------------QGAENLCIKLSEKLQSKTSSKVIIAHLPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVIPSPVLVKLYKYHSQYHTVAGNDIKIS---VTNEHSES-TLNVMSGKKSQP----------SMYEQLRDIAIDNICRCLKAGLTVDPVIVEAFLASLSNRLYISQESDKD-------AHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIIDQLGCLVITG-NQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAANIQDEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLTRRLPPIKEAKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSKEPLRS-VLQYNSAMKNDTVTPAELSELRSTIINLLDPPPE-VSALINKLDFAMSTYLLSVYRLEYMRVLRSTDPDRFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMADKAKTKENEEELERHAQFLLVNFNHIHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLS-ADIHKDQP--YYDIPDAPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNKQNTTLGATQLSERPACVKKDYSNFMASLNLRNRYAGEVYGMIRFSGTTGQMSDLNKMMVQDLHSALDRSHPQHYTQAMFKLTAMLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKDGVEVPFMREMAGAWHMTVEQKFGLFSAEIKEADP----------LAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLNIGGAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPT-QGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPP-------------------------------DNQD-------------TRSNLDITVGSRQQ-ATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQ-LHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELEL--DQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGD--ERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRG-QTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSRTYDMIQYYQNDIPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AWF4-1", "uniprot_id": "A0A8M3AWF4_DANRE", "id": "A0A8M3AWF4-1", "name": "Phosphatidylinositol 4-kinase alpha", "aln": "-----------------------MSSRGTSRGFYFNTVLSLARSLAAHRPAPIDKVQKLQCMCP-VDIRGVFQLDERRRDAVIALGI---FLVESELQHKDAIVPYLLVLLKGLPRVQWIEES-SERKGREALPIAENFSFCLVTVLSDVAQMDESMRIQILEAVMNLIQVLQETCQNIEGQDKE----YLCKYTVPCLLGVVRAFGRYSNTEEPLLSKLFP-RIVPQPPGTGDGAEVTRRRSFNDFRSILPSS--LLTVCQSDTLRRKTSSTSSISQQASPERAGLPPSSPSDPSAPYFEAASYLPDGSAVDPDYYFSTISSSFS-----VSPLFTGSN--NKEFTVPLDLLRQLLQMVEQFVSESFMKTLDQAMTEVLEINPTAYLYYKTFSDPLYVAIFKMLRDSLYYMKDLQVSFVKEVHDFVLEQFSSSQSELQRILHDVEYLHSELN------PLKLRCQANAACVDLMVWAVTEE--------------------QGAENLCTKLSEKLQSKTSSKVIIAHMPLLICCLQGLGRLCERFPVVAHSVTMSLRDFLVVPSPVLVKLYKYHSQYTTGAG-EIKIH---VTNEHSQS-TFSSHSSKKSQP----------SMYEQLRDISINNICRCLKAGLTMDSVIVEAFLASLSNRLYISQENDKD-------AHLIPDHTIRALGHIAVALRDTPRVMEPILQILQQKFCQPPSQLDVLIIDQLGCMVITG-NQYIYQEVWNLFQQISVKASSMVYS-TKDYKDHGYRHCSLAVINALANIAANLQTEQMVDELLVNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLTKRLPAIKEAKPRLQKLFRDFWLYSVVMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSGEPLRS-ELQYNSALKNDTVTPAELNDLRGTIINLLDPPPE-VAALINKLDFAMSTYLLSVYRLEYMRVLRSQESDRFQVMFRYFEDRAIQKDKSGMMQCVIAVGDKVFDVFLQMMADKAKTKAHEEELESHAQFLLVNFNHIHKRIRRVADKYLSGLAETFPHLLWSGRVLRTMLDILQTLSLSLS-ADIHKDQP--YYDIPDTPYRITVPDTYEARESIVKDFAARCGEILKEAMKWAPSVTKSHLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNRQSTSLGTTQLTERPACVKKDYSNFMASLNLRNRYAGEVAGMIHFSEATRSTSDLNKLMIRQMNEALDGGQPEAFTEALFKMAALLISSREWDPLLLHHLCWSPLKMFTENGMETAIACWEWLLAGRTGVEVPFMREMAGAWQMTVDLKMGLFSDAQLEADP----------LAASEESQPIPCPPDVTPHYIWIEFLVQRFEIAKYSSADQVEIFGSLLQRSLSLNVGSPKSSLNRHVAAIGPRFRLLTLGLSLLHSDVVTNATIRNVLREKIYSTAFDYFSVASKFPT-QGDKRLREDISIMIRFYASILSDKKYLGASLLVPPGELGANPPQSSLSAGIFGSLIVSSTSPISILNNQDPSLNSLSVMNATDPRNNMDMTVGSRQQ-SAQGWINTYPLSSGMSTTSKKSGMSKKSNRGTQ-LHKYYMKRRTLLLALLASEIERLSTWYNPLSTQELAIPTEQSVETSISNWRSKYINLTEKQWKDNVNLAWSIAPYLALQLPARFKNADAIVAEVTRLVRLDPGAVSDVPEAVKFLVTWHTIDADSPELSHILCWAPADPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAAQKSQLLAHQFIWNMKTNIFLDEEGHQKDPDIGELLEQMVEEITHSLSGPAKDFYQREFDFFNKITNVSAIIKPVPKGD--ERKRACLKALSEIKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCPSDSQDEGDESSLTAQRVCWQAAIFKVGDDCRQDMLALQIIGLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCKSRDQLGRQTDFGMYDYFRNQYGDESTLAFQKARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDSKGHLIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRG-QTIKLLKQRFNPNMSEKEAAAFMIKVIERCFLSSRSKTYDMLQYYQNQIPY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PDM4-1", "uniprot_id": "M9PDM4_DROME", "id": "M9PDM4-1", "name": "Phosphatidylinositol 4-kinase alpha", "aln": "-----------------------MTMTASDKYTYQRTVLCLARVLAGIQPTPWDKVQTLFRYCPQENAAGVFCLDTRAQDAVIALGI---YFLEGGCQHEGQIVPYLLRLAKCLPKAVWIDDARSNKVERVRIPSAEKFSFCLNTLLSDIAAKCPDSREEIILNQVETLSALANIVKSSRDSSSAPPPIILCKATVPLLFGLARSMGRYASNDPPLLCRIFPPELLPIQKGGGRDGTGSSSSASGTCGGSFSSSERLAATHHFRPIIPRSMSGSLAQAQNASYDDGRQRCAGGKPSKPSLHSYFSVPYDPRTHFFTRYGSSFNQFPNMRVCESPTKGGPRPLYRVPPFPIQHLQTIFAVSKKLLTKDTLEHLDEQASDIFSLHQIKGYCYKSFSETLNLVLVTLLRELLQHQVDLPTPFTKDVQEFVKRLFLNGQTELQNKQQDQERERREENGIAVVNKYKVNVMANAACVDLLVWAIRDETVDVDYNVPSLQNGLQFLLKKEADKLCGRLSQKLNLELSHKIVMDHMPLLMVCLEGLGKLAHKFPNIAGTSISYLRDFLVAPSPILGKLHDHAMQSLAQQKKEKELTPFKIAVQHSDSRTAVVIYGDNQKPPGSGTGRSGHAAFESLRDAAIENLSIALRAAHTLDQFCVPALVANVSNRLFTAEKSGSESQGECHKSNLVSLNIIVMLGHVAVALKDTSKTTQNILQFFIQRFCKVPSEQNALIVDQLGCMIISQCETHVFDEIMKMFSRVTVQSASLAYTSDPEHRKQ-FHHVSDAVVNALGNIAANIQGDAEMLELLGKLLELFVQIGLDGERSYDNTPG---AQKASSRAGNLGMLIPVIAVLVRRLPPIKNPRQRLHKLFKDFWAYCVVMGFTN--ARLWPADWYQGVQQIAAKSPLLISQTAHKSDMRELNYTLAIKSDSVN-----ELRSQILVLLEHSSDNVATAINKLSFAQCTYLLSVYWLEMLRVENADEPS-LEPIMSYLCDTALQRDKTGIWQCVKCVADQVFEKFRNVLYAHDEIR--EKVLESQATLLLVYFNHIHKPIQMVADQYLSFLVDRFPHLLWNRRVLWCMLDILQLLAYSLS-LDPNEETP--TLRVVSTPYTLQLMDSLPARELRLKDFADRCQGIVNEAMKWAPRSTRSHLQEYPNQIP--TPVLAHHSGLALAFDSVVSSS---AQHTG----TMSKRPSCVNSDTPRFVSVLCLRSKYAGEISGLLSVLSEK-DKAGLADRLVSDVWEACAEKSDARHRGALWRATAYLIICSEISRKLLHAVASSQLELFTESAMETAVECWQWVLTARQDLELCFIQEMVSAWQTTFEKRMGLFAWETEVTHP----------LAAYEGCKLVSKPILIAPHLIWLQLLSEMVDTAKYCNRDKVEMFCLLLHRCLPVLKSSKQ---NRQVSTVGCRFKLLQCGLSLLQGNTIPKSLSRNILRERIYSNALDYFCGPPTCPN-QSREQLLEDIMILLKFWQTMRSEKKHLVTSEVGDYDLTNASVSSTQMLAVRNNPETASLISGGGLVNDYTRSMS--------ASGNAVGMGMGVAGGGSSSGWYNTIPHST--STLSKRSNRSKRLQYQKDSYDKDYMKKRNLILELLAVELEFLITWYNPNSLPDLIVP----GEEQITEWRNR--PYKSTVWRDYARLAWCYNPALAVFLPQRIKNAEIIDEEVSRLVCSDPIAVCHIPEALKYLCTTKNLLQESPDLVYILSWSPVTPIQALAYFSRQYPSHPLTAQYAVKTLSSYPAESVLPYIPQLVQALRHDTMGYVVEFIKNISRRSQIVAHQLIWNMQTNMYMDEDQQHKDPNLYEALDQLSQSIIASFSGAAKRFYEREFDFFGKITAVSGEIRSFAKGI--ERKNACLAALSRIKVQGGCYLPSNPEAMVLDIDYSSGTPMQSAAKAPYLARFRVYRCGITELETRAMEVSNNPNSQ-EDAKMTLGVESWQAAIFKVGDDVRQDMLALQVITIFKNIFQQVGLDLFLFPYRVVATAPGCGVIECVPNAKSRDQLGRQTDSGLSEYFQHQYGDESSKEFQAARANFVKSMAAYSLIGYLLQIKDRHNGNIMIDKDGHIIHIDFGFMFESSPGGNIGFEPDMKLTDEMVMIMGGKMDSPAFKWFCELCVQAFLAVRPYQDAIVSLVSLMLDTGLPCFRG-QTINLLKQRFVATKNNKEAAAHMLAVIRNSYQNFRTRTYDMIQYYQNQIPY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P37297-1", "uniprot_id": "STT4_YEAST", "id": "P37297-1", "name": "Phosphatidylinositol 4-kinase STT4", "aln": "-----------------------MRFTRGLKASSSLRAKAIGRLTKLSTGAPNDQNSNGTTLDLITHTLPIFYSTNTSKIYTIPLTLSEWEVLTSLCVAIPTTLDLVETMLKEIIAPYFLETP------RQRISDVLSSKFKLEQMRNPIELLTFQLTKFMIQACEQYPVLYENIGGIISTYFER--VLKIFTIKQSGLLSLVGFINAFIQFPNSTELTKFTWKKLAKLVLRG--------SFLNEVDKILNSS----ATFTNDSIVQYYDAGNELSSAYLLELISRLQVSLISHLLNTSHVGANLSEFLLNQQYQFYKFDQEVAD-----ENDDTKCIDDFFFNVRSNKQFFTDMCKISLQFCSESHILDLSTDNRARFSFDTRAHYLQT-------LCLIPFIEDTESELFESFTNVVSESIDKFFLSDVVTPSLIKAIVASASLLN------------------------------------------------------------------FFTEKLSLTLIRMFPLLVASPHITTETVNDVAKIFTTGLYPLNEDAIVSTIYSMNNLLAVSEDGSPVPVLRERQ-------------LTITSGKNIEK----------DYFPLRNSSASLDGTGALLGNTTVGQLSSHDVNSGATMTYHAS-----------------LISNCVAATTTIASYYNTQSITALTISILTQKVNSMSKELDGVILNSLARLAPNT-SLTEFSLLLKFFKSRTVIATKIDDS-------ALLKNIIKAKCVISKELLARHFSSDLYFMYLHDLLDSIIASG-EVERLEHHRPQTEISRVADQIATYLEPLAALLPVPGDTPLDINK-DEVTTNKFRNAWFNFVIHGYHLG--GPIVKRNFSFLLTIAYNSPPLASEFPANNKELSLEMNTILRRGSSNENIKQQKQQITEYFNTNIVQYRTTSSSKIMFLAAAVLLETIRCEAGDCSKT---------LLYFSDPSILSG--SIEKCIAVLSVSMIRKYARLIQKGNDAIFNSKMIAQQLNNLLLCLSHREPTLQDAAFHACEIFIRSIPSSLCHHLSLYTLLDMLTALFDSILDSEAHKFEPRYEFKLKHSKTTILVPSSSSWRATTLSRLHKSAKEWVRILLNRSNQDTKILLQSYISDLGEYSRLNSVEFGVSFAMDMAGLILPADKELSR-----LTYYGPEKPNTISGFISLHSWRSKYLFDTA-ITSSPEDIKRQIGISTQNIRKNLTLGNKIITKDVTDFLDMATALLILGNGAPASLIYDIVHIPFEVFTSASLKIATNVWLTIITEKPEVAHLLLVEVCYCWMRSIDDNIGLYSRDHDLKGEEYQKMEYSPYDKAGINRDAKNASQAMQPHLHVIKFFASHFEGTLFQSDFLLKIFTKCALYGIKNLYKASLHPFARMIR-----HELLLFATLVLNASYKQGSKYMGRLSQEITNGALSWFKRPVAWPFGSNELKIKADLSVTRDLFLQLN----------------------------------------------------------------------------------------------------------KLSSLMSRHCGKDYKILNYFLASEIQQIQTWLTPTEKIEGAD--------------------SNELTSDIVEATFAKDPTLAINLLQRCYSKKAEDVLVG-LVAKHALMCVGSPSALDLFIKGSHLSSKK-DLHATLYWAPVSPLKSINLFLPEWQGNSFILQFSIYSLESQDVNLAFFYVPQIVQCLRYDKTGYVERLILDTAKISVLFSHQIIWNMLANCYKDDEGIQED-EIKPTLDRIRERMVSSFSQSHRDFYEREFEFFDEVTGISGKLKPYIKKSKAEKKHKIDEEMSKIEVKPDVYLPSNPDGVVIDIDRKSGKPLQSHAKAPFMATFKIKKDVKDPLTGK-----------------NKEVEKWQAAIFKVGDDCRQDVLALQLISLFRTIWSSIGLDVYVFPYRVTATAPGCGVIDVLPNSVSRDMLGREAVNGLYEYFTSKFGNESTIEFQNARNNFVKSLAGYSVISYLLQFKDRHNGNIMYDDQGHCLHIDFGFIFDIVPGGIKFEAVPFKLTKEMVKVMGGSPQTPAYLDFEELCIKAYLAARPHVEAIIECVNPMLGSGLPCFKGHKTIRNLRARFQPQKTDHEAALYMKALIRKSYESIFTKGYDEFQRLTNGIPY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .:.* :. :: .. . :* : .*.* : .: . : : : : : ::: . * :. . . .* * : . : . :: : . : . . *:.: :. : . . *. . . . : *. :. .: : . . : . :. . : . . : : : : :: : : *. :. . . : :. ::.: : . ...: : . :: . . . : : :: :***: . . . . .. : : *.: : .: : : : : ..: : : .. : : .* . *:. . . :. : . : .: :* :.:: *:. . .. : :*::.*. : . . :. : ::*. :* ::.: : :: * :: *. . * .**: :: * : :* .. . : *.. * * * .::.* *:: : *:: * *: *: :. : ** :** * *: . :: .: . : : : : :: .*: * .: **.. * .: : *: * :: . .: :*: :. .:: : .:: . .: : : **: :.* . :: .* : . : :* * * :**:* * *: : :: * : : : : .: * :. : . :. :: : *: **.* .. : . *:::* : : : :: . . . *:: *.:* : : .: : . : :* ** *:: : :.:*.. .:: * * ::: : : :: *: .* :.: .:**:: * . . : ** :.:: . .: : : . :::* : . * : ..** . :*:.. : . * :.* . *:.:* . * .. :: *: : :: : .. : * .:: :** *:: : ** .* . : .. * .. :: * **: * * . . * ** .. *.*:. : . : . :* * *:*. * .: * : :.: *:.: * * : : *:**:**.**:*. *** . * : * :.:**:**** :* : *:: ::* :: *::: : : *:* . : **:***:**.::* :*. ::. * *:*. :*.::*: . ******:.:*:*** .**.*:** ****::* *:: : * . *********** ***:****:* :*:.*:. :***:::*****.*********: :*:. *** ***:: *: :** ::*:**: ** ** **::*:*.**:: :***:********* *..** :******:*: *** :***.*** :***. ::..: * *:*::.:**.**: :*::. *. **.:*****:* :**. *: ** . .::*** .: :*. .: . :: ** :* * ***", "identical_positions": 318, "similar_positions": 573, "identity": "14.19%" }, { "cls_id": "homologset.agr.RGD:621214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08561-1", "uniprot_id": "PI4KB_RAT", "id": "O08561-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDMVVEP------------------------ATLKPTSEPTPS----------PSGNNGGS-------------------LLSVITEGVGELS-VIDPEV-AQKACQEVLEKVKLLHGGVAISSKGSPL---------------------------------------ELVNGDGVDNEIRCLDDP-------------------------PTEIREEEDEMEPGVVSGTAKGTRRRRQNNSAK------------------------------------------------------------------------------------------QSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKP--AHR--KRELPTLSP-----------APDTGLSPSKRTHQR---SKSDATASIS------------------------------------LSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPT------AGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN-FDTTNVPARIPENRIRSTRSVENLPECGITHEQ-----RAGSFSTVPN---------YDND---------DEAWSVDDIGELQVEL-------------------PEVHTN----------------SCDNISQFSVDS----------------------------------ITSQESKEPVFIAAGDIRRRLSEQLAHT-PTAFKRDPEDPS------------------AVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQL---------------SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLNGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHG--SSTIRNLKERFHMSMTEEQLQLLVEQMVDG-SMRSITTKLYDGFQYLTNGIM--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKC8-1", "uniprot_id": "PI4KB_MOUSE", "id": "Q8BKC8-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDMVVEP------------------------ATLKPTSEPTPS----------PSGNNGGS-------------------LLSVITEGVGELS-VIDPEV-AQKACQEVLEKVKLLHGGVAISSKGTPL---------------------------------------ELVNGDGVDNEIRCLDDP-------------------------PAQIREEEDEMGAGVASGTAKGARRRRQNNSAK------------------------------------------------------------------------------------------QSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFYFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKP--AHR--KRELPTLSP-----------APDTGLSPSKRTHQR---SKSDATASIS------------------------------------LSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPT------AGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN-FDTTSVPARIPENRIRSTRSVENLPECGITHEQ-----RAGSFSTVPN---------YDND---------DEAWSVDDIGELQVEL-------------------PEVHTN----------------SCDNISQFSVDS----------------------------------ITSQESKEPVFIAAGDIRRRLSEQLAHT-PTAFKRDPEDPS------------------AVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQL---------------SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLNGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHG--SSTIRNLKERFHMSMTEEQLQLLVEQMVDG-SMRSITTKLYDGFQYLTNGIM--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBF8-1", "uniprot_id": "PI4KB_HUMAN", "id": "Q9UBF8-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDTVVEP------------------------APLKPTSEPTSG----------PPGNNGGS-------------------LLSVITEGVGELS-VIDPEV-AQKACQEVLEKVKLLHGGVAVSSRGTPL---------------------------------------ELVNGDGVDSEIRCLDDP-------------------------PAQIREEEDEMGAAVASGTAKGARRRRQNNSAK------------------------------------------------------------------------------------------QSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKP--AHR--KRELPSLSP-----------APDTGLSPSKRTHQR---SKSDATASIS------------------------------------LSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPT------AGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN-FDTTSVPARIPENRIRSTRSVENLPECGITHEQ-----RAGSFSTVPN---------YDND---------DEAWSVDDIGELQVEL-------------------PEVHTN----------------SCDNISQFSVDS----------------------------------ITSQESKEPVFIAAGDIRRRLSEQLAHT-PTAFKRDPEDPS------------------AVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQL---------------SLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHG--SSTIRNLKERFHMSMTEEQLQLLVEQMVDG-SMRSITTKLYDGFQYLTNGIM--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q49GP3-1", "uniprot_id": "PI4KB_DANRE", "id": "Q49GP3-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDTELELSP-------THLEELQKSPSTSTTSSLSLPSSPSSG----------PHPLTSSSPSTSEG-------LPTSSPPLDVISEGLGELSLVIDTEV-AKKACQEVLQKVKFLKGDGEVSSASSEP---------------------------------------ILANG--TAHPEANDGGQ-------------------------PPKISEEE--------VEPIKSVRRRQKNNSSK------------------------------------------------------------------------------------------QSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFSFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYVVYRCRQSINFSLQCAWLLGAYSSDMHISTQRHSRGTKLRKLILSDELKP--SSQRIRREVPQPPPPYPPPLHHGPGMSEHSLSPSKRTHQR---SKSDATVSIS------------------------------------LSSNLKRTASNPKVETSQDE--------------PVRLTPQREFIKSLMGIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPT------AAFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECEN-FETSSVPVRIPETQIRSTRSVENLPDCGITPDQ-----RASSFSTVPN---------YDND---------DEAWSVDDIGELQVEL-------------------PEIHTN----------------SCDNISQFSVDS----------------------------------ITSQESKEPIFIAAGDIRRRLSEQLAHT-PTTFRKDPEDPS------------------AVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAYQVLKQLQIIWEQERVPLWIKPYKILVISSDSGMIEPVVNAVSIHQVKKQSQL---------------LLLDYFRQEHGNFNTEEFLTAQRNFVQSCAGYCLICYLLQVKDRHNGNILLDSEGHIIHIDFGFILSSSPRNLGFETSAFKLTSEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMEKVIQIVEIMQQGSQLPCFHG--SSTIRNLKERFHMNLTEEQLQVLVEQMVDG-SMRSITTKLYDGFQYLTNGIM--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A4D6K881-1", "uniprot_id": "A0A4D6K881_DROME", "id": "A0A4D6K881-1", "name": "Phosphatidylinositol 4-kinase beta", "aln": "MNSVISAFKGKKNSNPSCNSPMGSANGTAPVEAKPNNCYQYLRHIREIDTNNKLLSPVVVVAEERPVSKAGSPSTVATMATGVDVVDHCLPTTVRLSVTEALSDLNMNGKAVEPPVTPCTSVGDNANLEVAETWACPPPQATDDEDISEHSTAACTSTSSSSEHSNSTVVHSPTVGESTCDSVSVSVSHPSPSVSQNNTSSATGRMSSPHSQSSLSIACEPHSASTTTLSSLGSDLGNGNGSTVPAFLMAAPVTLPIGGQMPTIKCLPGASSAASTPKHSRYSKPRLSLSRVFNHSMPSVHGRPNLSLAPAGVPGSVNPPKRISTHQRNLSLDFRSMGILLPPVSQVTNNHINHTQHHRNRSLDSALQRIPEVEVSSPNAESENTFCSPSILGATMCSKIATTAATVTSALSPPGTPTPALMSTACTPTIGAVKGNVQHPVPKHEQSISLAAACRSSAVVESCPTLRMRPKSSESVAANGQEMIGVIVSSTGNGSSSSNNSCSSAGSTKKREDLTSLGSDDSGIICGSESDQISLNRICHSHESLDSGEMDADADAEEECVDLMDTTSIDEEYNIMQPDHLCLYPPQAASTELDCRTLRPSRKQKRQQQQVLERKNLPSQNQIESEDSVDAGVDARTRYRVMNMSQAAINVELGTASNEIDPDVNYRESHQDPIADAPSLSTPSVASTASATPSVTPTPIATPTPTESTKNDQVLFKNFFGATKNAIFRTAQSIIENHEKKNAAKQKEQPDHSGTVSLVGSPNGGSSVPQDLVKSPTDISKKKEFFSLLTSSSSIKAAAAAAANSAASTPPATPTEALAANSNSKLQPLSDPSADLKVKERTLNLRLPGDSEGSEGALTKCSSINSIHKLKLPVPGVVKYFISEKAPVSDVLQKPEKGQSGLLRFFESPVFNIHFAVHYLFYSKEPGVLSFIGNKIFSFPDQEVDLYIPQLVVMYIQMDELA-EVLDPYLTIRCRKSVDFSLKCLWLLEAYNYQVDSLGNSHNSSRKSKLALMKEIFSKR-EHKQTQNDLKSAGTG-----GLHVGEPRSVVALAKKTHHR---SQSDATVLLADFRSPHTLSISHRMYQQPPYTTQTLPTTPAKLCLGDLTSGHAFDNGCTCFETVRGQVNGLLGQRTLCSCGAPKTSPQKEFMKALMNVGKNLTSWPSKAEKTSALRMSLNLINKNLPARVWLPLY-----SDIPHHVVRITEEKTAVLNSKDKTPYIIYVEVVEIPD-IYTSPLIPKMMPS-LRHTKSEEHLDGSCLNSHQHLSCSRTSSCSSSQQGTSCRRKKGADVDGGCGDAGPHNSCSNVHSLGGLQFQE-------------------DDVWSQEEDEITAQYLNMRKVSERDTISQISLDS----------------------------------CDSRDQGPPVVFNIGDVRLRHCSNLSCENTKSFSNDPEDPS------------------AAALKEPWHEKEKLIRESSPYGHLSNWRLLSAIVKCGDDLRQELMATQLLQMFKIIWQEEQVDLWVRPYKIVCLSNDSGLIEPILNTVSLHQIKKNSNK---------------SLKEYFIDEYGSPSGESFRRAQKNFVQSCAAYCLISYLLQVKDRHNGNILFHSDGHIIHIDFGFILSISPKNLGFEQSPFKLTPEFVEVMGGTSSEHWREFNKLLLVGMMSARKHMDRIINFVEIMRSNAHLPCFKNGCSGTVQNLRKRFHMNLTEQEMERKVEQLVQD-SLKSLSTKLYDGYQYYTNGILXERFFMKI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39104-1", "uniprot_id": "PIK1_YEAST", "id": "P39104-1", "name": "Phosphatidylinositol 4-kinase PIK1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHKASSSKKSFDDTIELKKNEQLLKLINSSEFTLHNCVELLCKHSENIGIHYYLCQKLATFPHSELQFYIPQLVQVLVTMETESMALED-----------------------LLLRLRAENPHFALLTFWQLQALLTDLSTDPASYG-------FQVARRVLNNLQTNLFNTSSGSDKNVKIHENVAPALVLSSMIMSAIAFPQLSEVT--------------------------------------KPLVESQGRRQKAFVFKLAR-------------------------SAMKDFTKNMTLKNTLLNKKTSRSKRVSSNRS------------------------------------------------------------------------------------------------STPTSPIDLIDPIKTKEDASFRKSRHSEVKLDFDIVDDIGNQVFEERISSSIKLPKRKPKYLDNSYVHRTYDGKNINRDGSISNTAKALDGNKGDYISPKGRNDENNEIGNNEDETGGETEEDADALNSDHFTSSMPDLHNIQPRTSSASSASLEGTPKLNRTNSQP--------------------------------------LSRQAFKNSKKANSSLSQEIDLSQLSTTSKIKMLKANYFRCETQFAIALETISQRLARVPTEAR-LSALRAELFLLNRDLPAEVDIPTLLPPNKKGKLHKLVTITANEAQVLNSAEKVPYLLLIEYLRDEFDFDPTSETNERLLKKISGNQGGLIFDLNYMNRKENNENRNESTLTSNNTRSSVYDSNSFNNGASRNEGLSSTSRSDSASTAHVRTEVNKEEDLGDMSMVKVRNRTDDEAYRNALVIQSAANVPILPDDSQDRSPELNFGSNLDEVLIENGINSKNIHSQTDALADQMRVSAVMLAQLDKSPQQLSESTKQIRAQIISSMKEVQDKFGYHDLEALHGMAGERKLENDLMTGGIDTSYLGEDWATKKERIRKTSEYGHFENWDLCSVIAKTGDDLRQEAFAYQMIQAMANIWVKEKVDVWVKRMKILITSANTGLVETITNAMSVHSIKKALTKKMIEDAELDDKGGIASLNDHFLRAFGNPNGFKYRRAQDNFASSLAAYSVICYLLQVKDRHNGNIMIDNEGHVSHIDFGFMLSNSPGSVGFEAAPFKLTYEYIELLGGVEGEAFKKFVELTKSSFKALRKYADQIVSMCEIMQKDNMQPCFDAG-EQTSVQLRQRFQLDLSEKEVDDFVENFLIGKSLGSIYTRIYDQFQLITQGIYS-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * . . : : : * * :* :: : : . . : :. . : . * .. . : ::: .: :. : * : :: : : : : *:: : . :. . * .. ::. . * : . . : . : : . : . : : . .:::: . . : . : :* :* :.:.*: *:: . . * .* *:*:.***.* :* *::* :. :: **** :*.**:: :* :. : .: . . : .:. : :. .: . .: :: : . . . . . :: : : : . * .::...* .. : ::* : ..: . .* * : * * * * . **: * ***: ** * *.*.* ******* :* *::: : ** :*:* :*:: **: * ::*::*.: *::*:*.:** * ::* .*. . : ** **..* *.*.::.*************::. :**: ******:** ** .:*** :.**** *:::::** ..: :. : * .: : **: ::::.: ***:.. ***. . * :*::**::.::*:::: **::: . *: *: *::** :* *:** ", "identical_positions": 148, "similar_positions": 251, "identity": "8.29%" }, { "cls_id": "homologset.agr.RGD:621215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7K0-1", "uniprot_id": "G3V7K0_RAT", "id": "G3V7K0-1", "name": "Visual system homeobox 2", "aln": "-----------------------------MTGKAGEALSK--PKSETVAKSTSGG---------------------------------APARCTGFGIQEILGLNKEPPSSHPRAALDGLAPG-HLLAA----------------------------RSVLSP------------------------------------------------------------------------------------------AGVGS--------------MGLLGPGGLPGFYAQPT-----------------------FLEVLSDPQSVHLQPLGRASGPLDTSQTASSDSEDVSSSDRKMSKSALNQT-----------------------------KKRKKRRH-RTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLP---------------------ESILKSAKDGIMDSCAPWLLGMHKKSLEAAAE-SGRKPE-------------------------------------------------------------------------------------------------------------------------------------VERQ-VLPKLDKMEQEERAPDAQAAISQ-----------EELRENSIAALRAKAQEHS-----------TKVLGTVSGPDGLARNAEKPEEEEAMDEDRPAEKLSPPQLEDMA---------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61412-1", "uniprot_id": "VSX2_MOUSE", "id": "Q61412-1", "name": "Visual system homeobox 2", "aln": "-----------------------------MTGKAGEALSK--PKSETVAKSTSGG---------------------------------APARCTGFGIQEILGLNKEPPSSHPRAALDGLAPG-HLLAA----------------------------RSVLSP------------------------------------------------------------------------------------------AGVGS--------------MGLLGPGGLPGFYTQPT-----------------------FLEVLSDPQSVHLQPLGRASGPLDTSQTASSDSEDVSSSDRKMSKSALNQT-----------------------------KKRKKRRH-RTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLP---------------------ESILKSAKDGIMDSCAPWLLGMHKKSLEAAAE-SGRKPE-------------------------------------------------------------------------------------------------------------------------------------VERQ-ALPKLDKMEQEERAPEAQAAISQ-----------EELRENSIAALRAKAQEHS-----------TKVLGTVSGPDSLARNAEKPEEEDATEEDRPAEKLSPPQLEDMA---------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P58304-1", "uniprot_id": "VSX2_HUMAN", "id": "P58304-1", "name": "Visual system homeobox 2", "aln": "-----------------------------MTGKAGEALSK--PKSETVAKSTSGG---------------------------------APARCTGFGIQEILGLNKEPPSSHPRAALDGLAPG-HLLAA----------------------------RSVLSP------------------------------------------------------------------------------------------AGVGG--------------MGLLGPGGLPGFYTQPT-----------------------FLEVLSDPQSVHLQPLGRASGPLDTSQTASSDSEDVSSSDRKMSKSALNQT-----------------------------KKRKKRRH-RTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLP---------------------ESILKSAKDGIMDSCAPWLLGMHKKSLEAAAE-SGRKPE-------------------------------------------------------------------------------------------------------------------------------------GERQ-ALPKLDKMEQDERGPDAQAAISQ-----------EELRENSIAVLRAKAQEHS-----------TKVLGTVSGPDSLARSTEKPEEEEAMDEDRPAERLSPPQLEDMA---------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O42477-1", "uniprot_id": "VSX2_DANRE", "id": "O42477-1", "name": "Visual system homeobox 2", "aln": "-----------------------------MTGKDGAVLSESLNKSKSLCATENGGNNNPHLSKSSIT---------------------HPPKCTGFGIQEILGLNKEP-SSAPRSTLDSFPAGAHLLAS----------------------------RSMLGP------------------------------------------------------------------------------------------AGVGVGVG-----------MGLIGPGGIPSFYSQPA-----------------------FLEVLSDAQNVHLQPLSRTVGPLEHNQSASSDSDDVSSSERKMSKSSLSQS-----------------------------KKRKKRRH-RTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPVQDGFPTTSCFSKHEYPPFFAESILKSAKDGIMDSCAPWLLGMHKKSLETAGHQSNEKSD-------------------------------------------------------------------------------------------------------------------------------------VTQTPTNPKPDEAEAEER--RTESPMSK-----------EELRENSIAALRAKAQEHS-----------AKVLGTVS-SERLEHNMETTATE-----EKSSEQIDAKEEEKSS---------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4B2-1", "uniprot_id": "Q9W4B2_DROME", "id": "Q9W4B2-1", "name": "", "aln": "MQATKMRTPFAIQEILGLGAYQQQAT---ASATPSEAPPSPAATPPPTANTPANGSLSAVQQQQQQQQQQQQQQQQLQQQQQQAIDSLRESRSISPDVSRLSAAAAAAAAAAAHCQLPVFNPANFYAAAGYAAAADPGNAAAAHHHHMTTLAAAAYLRGFLPPGFSTPHEFRGHFQQHFGAQFAEQAAARGQEYASSLANASGDEQSPSKNSSSSGNGGSGGSGSGSGGGNPTSNGLGHLGSPTASNGGSGGGAGVGGSGGGSGTSGSNSSTSGNGGNGGSSGSRSSPAGPHHSAALAAHQHAAAAAAAAHHHAAAAAAAHHAHHAHAQAHAHAHAHVHAHAAHAAHAAHAHAHHAEAFLGAAGGAGGNPNSLLAAHGGDVLVGPGGTGPGGKKKNKRRHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTEKCWGHSTKMAEYGLYGAMVRHSLPLP---------------------ETIIKSAKE--DESVAPWLLGMHKKSLEAAELLKSDESDRETPTSDDTNTSYSAGSTHNSPISSFSISRLLFDAPPPAAGSAGGKGHHHHHHHHKGHHHAHVHAQAQAHAHMLLHHQQQQQQQQQQQQHHHHLHAAENSLQQQQVAGTGSGSGSGSGSGTGAGSTGPPAHHPYNQQQHLHHLQQLQQQQQQQQQQAQQQQQHHHHQHHHSVHHMHHHNAAAGYAEAAVAA-----------AAAAAAVAAAANARNAAAAAAVAAASASASAAVTIAESEAEEEQDDIEDMELDKD-CEVEEDVEPVDNDTNTNNEHDNECDADADVEADVDADADADPEIDICDDHDEEMRLQEQLLLKVKQEQAHLGSR-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "X2JDS9-1", "uniprot_id": "X2JDS9_DROME", "id": "X2JDS9-1", "name": "Visual system homeobox 2", "aln": "---MPQRSPFAIQELLGLAVAAATEAPTDLTTTAGATVAKERQTPTPPKTTNATMATAATSAATAATPTN---------------AAEGNLTSVSEPQQQPQQQQQEQQHHQPHHHQYREHHQMTMAAAS---------------------------RMAYFN----------------------------------------------------------------------------------------AHAAVAAAFMPHQLAAAVHHHHQHQHQHHPHHHPHHPHG----------------------AVGGPPPPPPMQHHHPHHPHHPLLHAQGFPQLKSFAAGAGTCLPGSLAPKDFG-------------MESLNGFGVGPNSKKKKKKRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTEKVWGGSTIMAEYGLYGAMVRHSLPLP---------------------DTILKSAKD--NDAVAPWLLGMEQKCMHRKSIEAQSALKDDSGVSDHEDSAGSKS----------------------------------------------AHSEDLSRSRCHALSSSTESLNVVSPAPSSCPTSASTSAPPTSTSGYAGAASSAATTPTGASTTNSSSSPHIELGSPSPQQQQHLQLQQQQQQQASLYLGAGAVVTGCAPPSYHPLLDAANAAGAGAAASSKDFHMIMNTAVAAAAAAAQQQHQQQQQQQQQATATAPGLHAHNLAAALMEHDPDAFRNNSIACLRAKAQEHQARLLNNGGLFLQVRRFAQGQAQIQDPSDMLKLSEEHNNNSPIPIPPAHSTVNTQVNVKMELTANGGSMKNYEEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . .. .. . : . . .. .: *: * *.*. * . . : . : . .: : . : **::**** ****** ***:**:**:******* ***:*::** *.*******:********* ** ** *: **************:*** ::*:****: :: *******.:*.:. . : :: :: :: : *. * * : : . .:.: . : : *. ", "identical_positions": 93, "similar_positions": 74, "identity": "10.54%" }, { "cls_id": "homologset.agr.RGD:621216", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54702-1", "uniprot_id": "CHSTA_RAT", "id": "O54702-1", "name": "Carbohydrate sulfotransferase 10", "aln": "------------MHHQWLLLAACFWVIFMFMVASKFITLTFKDPDGYSAKQEFVFLTAMPEAEKLRGEKHFS--------------------------------------------EVMKPTGKMLSESHP------DQPPVYL---ERLELIRNACKEEALRNLSHTEVSKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGAFSSIEEIPENVVHDHEKNGLPRLSSFSKIGIQKRLKTYFKFFIVRDPFERLISAFKDKFVHNPRFEPWYRHEIAPGIIRKYRK---NRTETRGIQFEDFVRYLGDPN-RRWLDLQFGDHIIHWVTYVKLCAPCEIKYSVIGHHETLEADAPYILKEAGIDHLVSYPTIPPGITMYNRTKVEQYFLGISKRDIRRLYARFEGDFKLFGYQKPDFLLN--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGK7-1", "uniprot_id": "CHSTA_MOUSE", "id": "Q6PGK7-1", "name": "Carbohydrate sulfotransferase 10", "aln": "------------MHHQWLLLAACFWVIFMFMVASKFITLTFKDPDGYSAKQEFVFLTTMPEAEKLRGEKHFP--------------------------------------------EVPKPTGKMLSDSRP------DQPPVYL---ERLELIRNTCKEEALRNLSHTEVSKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGAFSSIEEIPENVVHDHEKNGLPRLSSFSKIGIQKRLKTYFKFFIVRDPFERLISAFKDKFVHNPRFEPWYRHEIAPGIIRKYRK---NRTETRGIQFEDFVRYLGDPN-RRWLDLQFGDHIIHWVTYVELCAPCEIKYSVVGHHETLEADAPYILKEAGIDHLVSYPTIPPGITMYNRTKVEQYFLGISKRDIRRLYARFEGDFKLFGYQKPDFLLN--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43529-1", "uniprot_id": "CHSTA_HUMAN", "id": "O43529-1", "name": "Carbohydrate sulfotransferase 10", "aln": "------------MHHQWLLLAACFWVIFMFMVASKFITLTFKDPDVYSAKQEFLFLTTMPEVRKLPEEKHIP--------------------------------------------EELKPTGKELPDSQL------VQPLVYM---ERLELIRNVCRDDALKNLSHTPVSKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGAFSSIEEIPENVVHDHEKNGLPRLSSFSDAEIQKRLKTYFKFFIVRDPFERLISAFKDKFVHNPRFEPWYRHEIAPGIIRKYRR---NRTETRGIQFEDFVRYLGDPN-HRWLDLQFGDHIIHWVTYVELCAPCEIMYSVIGHHETLEDDAPYILKEAGIDHLVSYPTIPPGITVYNRTKVEHYFLGISKRDIRRLYARFEGDFKLFGYQKPDFLLN--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AXM1-1", "uniprot_id": "CHSTA_DANRE", "id": "Q6AXM1-1", "name": "Carbohydrate sulfotransferase 10", "aln": "------------MRRHWLLVGACGWVLLILMFVSKFINFSFRIPGDYAGRSEIFVWTLSSVTTKLP-SVVWP--------------------------------------------EKGASQPYILSSVSPSVVEPIDWHLVNE---KRLEQLSTVCSNSSIWNLTHTTVRKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGKFSKVEAIPENLVHDHERNGLPRLSSMTDTEIHQRLNSYFKFFIVRDPFERLISAFKDKFVKNPRFEPWYKHDIAPAIVRKYRRSHHDDSESVGLRFEDFVRYLGDKTGRQHLDRQFGDHIIHWLTYAELCAPCDISYNVVGHHETLELDAPYILKSAGIAGLVSYPSIPPGITRYNRTKVERYFSGISQRDIRRLYARYQGDFSLFDYPKPAFLLN--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRG5-1", "uniprot_id": "Q8IRG5_DROME", "id": "Q8IRG5-1", "name": "Carbohydrate sulfotransferase", "aln": "MKLSKSLANCRAIRRYLLIFTAVSLLLLPLSLAYLVWNEQLQKIRGFEAFNVQQQSPQQPQPQQQQQEQQQQPQQHGQFPYPVVRYPVLLLNKNKNKDLTVVATGKTKNKWRYVDKDSNQTLLPLIPEHAVQTLTPQEMLQVEQRMDQRRERLKDKCSAYGLDVLGHDAWHTPNTWEFLVNKKYHIIWCNVFKAASSSWMFNFNVLAGYSPSYLRKTKKILLNLARERYPRVT---LDELREAQNYSVTFIIARDPFERLLSAYRDKMVFALPYS--FHDKLGRSIVRNYRKKPSLAARAANTKFPSFPEFVHWLLDQVKRGSFID---MHFVAATSFCTPCLIRFDMILKFESLAEDQLYLIEKTGLKRVIAPVWRNMGKGRKTHELQQQFYAQLTRQEMLELYEYYKYDFELFDYDIQEYLQVARPDEAESPAGTKN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: *:. * ::: : .. . . :: : . . . . : . : . :.. * :* * : * .: * * . .::* .*::*::*:. *...:.* : ** * .. .:::: : :: **:: ::: : ..*:*.*******:**::**:* :. ::..:. .*:*:**: :.: . :* .* .:: : . :. :*::: ..:*:** * :.:: :.*:* * *:::.:*: ::: * .: :::: :::::: .** :: **.**.* :* ", "identical_positions": 58, "similar_positions": 139, "identity": "13.21%" }, { "cls_id": "homologset.agr.RGD:621217", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PK0-1", "uniprot_id": "SYF1_RAT", "id": "Q99PK0-1", "name": "Pre-mRNA-splicing factor SYF1", "aln": "--MVVMARVPRPERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFK--QGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYR-----------------------------------------------RFLKLSPES-AEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESM---IAAKMET-ASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPF--KATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALKLLRKATALPARRAEYFDGSE------PVQNRVYKSLKVWSMLADLEESLG---------TFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFISR-YGGRKLERARDLFEQALDGCPP--KYAKTLYLLYAQLEEEWG-LARHAMAVYDR------ATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIREMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPPRAQSKIFFVRSDASREELAELAQQANPEEIQLG------EDEDEDEMDLEPNE-------------------VRLEQQSVPAAVFGSLKED--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCD2-1", "uniprot_id": "SYF1_MOUSE", "id": "Q9DCD2-1", "name": "Pre-mRNA-splicing factor SYF1", "aln": "--MVVMARVPRSERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFK--QGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYR-----------------------------------------------RFLKLSPES-AEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESM---IAAKMET-ASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPF--KATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALKLLRKATALPARRAEYFDGSE------PVQNRVYKSLKVWSMLADLEESLG---------TFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFISR-YGGRKLERARDLFEQALDGCPP--KYAKTLYLLYAQLEEEWG-LARHAMAVYDR------ATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIREMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPPRAQSKIFFVRSDASREELAELAQQANPEEIQLG------EDEDEDEMDLEPNE-------------------VRLEQQSVPAAVFGSLKED--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCS7-1", "uniprot_id": "SYF1_HUMAN", "id": "Q9HCS7-1", "name": "Pre-mRNA-splicing factor SYF1", "aln": "--MVVMARLSRPERPDLVFEEEDLPYEEEIMRNQFSVKCWLRYIEFK--QGAPKPRLNQLYERALKLLPCSYKLWYRYLKARRAQVKHRCVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRFLRSHPLPETAVRGYR-----------------------------------------------RFLKLSPES-AEEYIEYLKSSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESM---IAAKMET-ASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPF--KATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSE------PVQNRVYKSLKVWSMLADLEESLG---------TFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIAR-YGGRKLERARDLFEQALDGCPP--KYAKTLYLLYAQLEEEWG-LARHAMAVYER------ATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIKEMLRIRRSVQATYNTQVNFMASQMLKVSGSATGTVSDLAPGQSGMDDMKLLEQRAEQLAAEAERDQPLRAQSKILFVRSDASREELAELAQQVNPEEIQLG------EDEDEDEMDLEPNE-------------------VRLEQQSVPAAVFGSLKED--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z9G2-1", "uniprot_id": "SYF1_DROME", "id": "A1Z9G2-1", "name": "Pre-mRNA-splicing factor syf1 homolog", "aln": "----MVTKTIKSLNLEINFEVEDVPYEEEILRNAYSVKHWLRYIDHK--AKAPNNGVNMVYERALKELPGSYKIWHNYLRTRRKQVRGKIPTDPMYEEVNSAFERALVFMHKMPRIWMDYGAFMTSQCKITRTRHVFDRALRALPITQHGRIWPLYLQFVRRFEMPETALRVYR-----------------------------------------------RYLKLFPED-TEEYVDYLQEADRLDEAAQQLAHIVDNEHFVSKHGKSNHQLWNELCDLISKNPHKVHSLNVDAIIRGGLRRYTDQLGHLWNSLADYYVRSGLFDRARDIYEEAIQTVTTVRDFTQVFDEYAQFEELS---LNRRMEQVAANEAATEEDDIDVELRLSRFEYLMERRLLLLNSVLLRQNPHNVHEWHKRVTLYEDKPAEIISTYTEAVQTVQPK--QAVGKLHTLWVEFAKFYEANGQVEDARVVFERGTEVEYVKVEDLAAVWCEWAEMELRQQQFEAALKLMQRATAMPKRKIAYYDDTE------TVQARLHRSLKVWSMYADLEESFG---------TFKTCKAVYERIIDLKICTPQIIINYGMFLEEHNYFEEAYRAYEKGISLFKWPNVYDIWNSYLTKFLER-YGGTKLERARDLFEQCLDQCPP--EHAKYFYLLYAKLEEEHG-LARHAMSVYDR------ATSAVKEDEMFDMYNIFIKKAAEIYGLPRTREIYEKAIESLPEQNMRHMCVKFAELETKLGEVDRARAIYAHCSQVCDPRITADFWQTWKEFEVRHGNEDTMREMLRIKRSVQATYNTQVNMMAAQFLSTN---NGAAADAGAG-AGPDAMRLLEEKARQAAAESKQKPIEKAASNIMFVRGETQGGAKDKKDTVVNPDEIDIGDSDEDDEEEDDDEENEMTNENQASAAVTKTDEEGLVMKKLRFEQKAIPAKVFGSLKPSNQGDSDGE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04048-1", "uniprot_id": "SYF1_YEAST", "id": "Q04048-1", "name": "Pre-mRNA-splicing factor SYF1", "aln": "MSAYIAMKGVITNVDENIRNDEDVAFEYEIQKTPQNILTWKRYIEYWKEEGRTDKQIRWLYERFCSQFVTDTSIWEDYIRWES--TKEVVETSRIFWLFQRCLK---SCVRDCDRICLSYLELAIEQYDLAMIRHALASSLMKMEREMHRKVWDPVIKFVEEKVLPLTQLDSTQEDEEESTDEAELINVLLVKGFTKGGFISEEISENGSRGDIWSSHILERYLKVAPQQKRNESLATLALTRDNITIKSVYEKYLPQDENSGKYLPSSELPFELNFNYLASLEKLGLDNQYEEFMRQMNGIYPDKWLFLILSLAKYYISRGRLDSCGDLLKKSLQQTLRYSDFDRIYNFYLLFEQECSQFILGKLKENDSKFFNQKDWTEKLQAHMATFESLINLYDIYLNDVALRQDSNLVETWMKRVSLQKS-AAEKCNVYSEAILKIDPRKVGTPGSFGRLWCSYGDLYWRSNAISTARELWTQSLKVPYPYIEDLEEIYLNWADRELDKEGVERAFSILEDALHVPTNPEILLEKYKNGHRKIPAQTVLFNSLRIWSKYIDYLEAYCPKDANSSDKIFNKTKMAYNTVIDLRLITPAMAENFALFLQNHYEVMESFQVYEKTIPLFPPEIQYELWIEYLEVATSHQLSSLSPEHIRFLFEKALKNLCSNGIDCKTIFIAYSVFEERISGLISKSIEILRRGAVIGTVSVSTHLESRLQLWRMCISKAESTLGPSVTRELYQECIQILPNSKAVEFVIKFSDFESSIGETIRAREILAYGAKLLPPSRNTELWDSFEIFELKHGDKETYKDMLKMKKVLESN-------------------------------------MLIDSASVSHEEGNINFVAAATSHAPNSHTLTQSTS----SYSINPDEIELDI-----------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : **:.:* ** :. .: * ***:. .. :. :*** . : . .:* *:: . .: *. : .: . : ::. *: :.* : .* :: *:.: :* : * ::* ::*:. :* * : : *:**: *:. :* : * : . : ::. .* *. :. : ::. . . : : ::* :.*: * ***.**: * :: . *: ::::: . ** :::: * **: : ::: :: :: .:: ::: ** *:. : **.* ***:.: *. * ***:* :. . * ..*:**: .::* : *. ** :..:* .. :. ** : :. :* : ::** :: : .: ** :: : *: ::. * :* . : : ..* :..**::** * *: *:. * .*: ::**:: ** : *:.:**::* . *:::.**: *.** ::* ** : .. . *: * ***:.*. . .* ::: *: :**. . * ::: : * .: :.. . :::.: *.:* . * . ** :*::.*: *.:.: .: ::*:::* .:** *** * :. ::: * . :*:::: **::**:::* ::**:::: :::. :* : * *.: . * *: : :. **:**::. ", "identical_positions": 155, "similar_positions": 295, "identity": "15.96%" }, { "cls_id": "homologset.agr.RGD:621218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O89000-1", "uniprot_id": "DPYD_RAT", "id": "O89000-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAG--VLSRDAPDIESILA----------------------------------------------------------------LNPRIQAHATLRSTMAKKLDKKHWKRNT-----------------------DKNCFICEKLENNFDDIKHTT----------------LGERGALREAVRCLKCADAPCQKSCPTSLDIKSFITSIANKNYYGAAKLIFSDNPLG---------------LTCG--MVCPTSDLCVGGCNLHATEEGPINIGGLQQFATEVFKAMNIPQIRSPL-----------------------------------------LPPPEHMPEAYSAKIALFGAGPASISCASFLARLG---------------------------------YSDITIFEKQEYVGG---------------------------LSTSEIPQFRLPYDVVNFEIELMKDLGVK------------------------IICGKSISTDEMTLSTLKEN----------------------------GYKAAFIGIGLP------------EPKKDHIFQGLTQVQGFYTSKDFLPLVAKGSKPGMCACHSP-----LPSVRGAVIVLGAG------DTAFDCATSALR-----CGARRVFIVFRKGFANIRAVPEEMELAKEEKCEFLP-----------FLSPRKVIVKDGKIVGMQFVRTEQDETGNWVEDEEQIVRLKADVVIS-------------------PFGSVLDDPKVIEALSPIKFNRWGLP------------EVNPETMQTSEPWVFAG---------GDVVGMANTTVESVNDGKQASWYIHEYIQAQYGALVPSQPT----LPLFYTPVDLVDISVEMAGLRFPNPFG--------------LASATPATSTPMIRRAFEAG----------------WGFALTKTFS------LDKDIVTNVSPRIIR--GTTSGPLYGPGQSSFLNIELISE-----------------------------KTAAYWCHSVTELKADFPDNILIASIMCSYNKNDWMELSKMAEASGADALELNLS---CPHGMGERGMG--LACGQDPELVRNICRWVRQSVRVPFFAKLTPNVTDIVS----------IARAAKEGGADGVTATNTVSGLMG-----------------LKADGSPWPSVGS-----------------------GKRTTYGGVSGTTIRPIALRAVTAIARALPGFPILATGG-------------IDSAESGLQFLHSGASVLQVCSAIQNQDFT--------VIEDYCTGLKALLYLKSIEELSD---WDGQS---------------------PPTMSHQKGKPVPHIAELMGQKLPSFGPYLERRKKILAASKIR--ENDQNRACSPLQRKHFNSQKP-IPAIKDVIGKSLQYLGTFGELNIME------------------------------QVVALIDEEMCINCGKCYMTCND--------SGYQAIQFDPETHLPTVSDTCTG------CTLCLSVCP--------------------IMDCIRMVSRATPYEPKRGLPLAVKPVC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHR6-1", "uniprot_id": "DPYD_MOUSE", "id": "Q8CHR6-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAG--VLSRDAPDIESILA----------------------------------------------------------------LNPRVQAHATLRSTAAKKLDKKHWKRNT-----------------------DKNCFTCEKLESNFDDIKHTT----------------LGERGALREAVRCLKCADAPCQKSCPTSLDIKSFITSIANKNYYGAAKLIFSDNPLG---------------LTCG--MVCPTSDLCVGGCNLHAAEEGPINIGGLQQFATEVFKAMNIPQIRNPS-----------------------------------------LPPPEHMPEAYSAKIALFGAGPASISCASFLARLG---------------------------------YSNITIFEKQEYVGG---------------------------LSTSEIPQFRLPYDVVNFEIELMKDLGVK------------------------IICGKSLSTDEMTLSSLKEN----------------------------GYRAAFIGIGLP------------EPKKDHIFQGLTQVQGFYTSKDFLPLVAKSSKTGMCACHSP-----LPSIRGAVIVLGAG------DTAFDCATSALR-----CGALRVFIVFRKGFVNIRAVPEEMELAKEEKCEFLP-----------FLSPRKVIVKDGKIVAMQFVRTEQDETGNWVEDEEQTVRLKADVVIS-------------------AFGSVLEDPKVKEALSPIKFNRWGLP------------EVNPETMQTSEPWVFAG---------GDVVGMANTTVESVNDGKQASWYIHKHIQAQYGTSVPSQPT----MPLFYTPVDLVDISVEMAGLRFPNPFG--------------LASATPATSTPMIRRAFEAG----------------WGFALTKTFS------LDKDIVTNVSPRIIR--GTTSGPLYGPGQSSFLNIELISE-----------------------------KTAAYWCHSVTELKADFPDNILIASIMCSYNKSDWMELSKMAEASGADALELNLS---CPHGMGERGMG--LACGQDPELVRNICRWVRQAVRVPFFAKLTPNVTDIVS----------IARAAKEGGADGVTATNTVSGLMG-----------------LKADGTPWPAVGI-----------------------GRRTTYGGVSGTAIRPIALRAVTAIARALPGFPILATGG-------------IDSAESGLQFLHSGASVLQVCSAIQNQDFT--------VIEDYCTGLKALLYLKSIEELAD---WDGQS---------------------PPIISHQKGKPVPRVAELMGQKLPSFGPYLEQRKKIIAASKIR--QKDQNTACSPLQRKHFNSQKP-IPAIKDVIGKSLQYLGTFGEMSIME------------------------------QVVALIDEEMCINCGKCYMTCND--------SGYQAIQFDPETHLPTVSDTCTG------CTLCLSVCP--------------------IMDCIRMVSRATPYQPKRGLPLAVKPVC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12882-1", "uniprot_id": "DPYD_HUMAN", "id": "Q12882-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAP--VLSKDSADIESILA----------------------------------------------------------------LNPRTQTHATLCSTSAKKLDKKHWKRNP-----------------------DKNCFNCEKLENNFDDIKHTT----------------LGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLG---------------LTCG--MVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIPQIRNPS-----------------------------------------LPPPEKMSEAYSAKIALFGAGPASISCASFLARLG---------------------------------YSDITIFEKQEYVGG---------------------------LSTSEIPQFRLPYDVVNFEIELMKDLGVK------------------------IICGKSLSVNEMTLSTLKEK----------------------------GYKAAFIGIGLP------------EPNKDAIFQGLTQDQGFYTSKDFLPLVAKGSKAGMCACHSP-----LPSIRGVVIVLGAG------DTAFDCATSALR-----CGARRVFIVFRKGFVNIRAVPEEMELAKEEKCEFLP-----------FLSPRKVIVKGGRIVAMQFVRTEQDETGKWNEDEDQMVHLKADVVIS-------------------AFGSVLSDPKVKEALSPIKFNRWGLP------------EVDPETMQTSEAWVFAG---------GDVVGLANTTVESVNDGKQASWYIHKYVQSQYGASVSAKPE----LPLFYTPIDLVDISVEMAGLKFINPFG--------------LASATPATSTSMIRRAFEAG----------------WGFALTKTFS------LDKDIVTNVSPRIIR--GTTSGPMYGPGQSSFLNIELISE-----------------------------KTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLS---CPHGMGERGMG--LACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVS----------IARAAKEGGANGVTATNTVSGLMG-----------------LKSDGTPWPAVGI-----------------------AKRTTYGGVSGTAIRPIALRAVTSIARALPGFPILATGG-------------IDSAESGLQFLHSGASVLQVCSAIQNQDFT--------VIEDYCTGLKALLYLKSIEELQD---WDGQS---------------------PATVSHQKGKPVPRIAELMDKKLPSFGPYLEQRKKIIAENKIR--LKEQNVAFSPLKRNCFIPKRP-IPTIKDVIGKALQYLGTFGELSNVE------------------------------QVVAMIDEEMCINCGKCYMTCND--------SGYQAIQFDPETHLPTITDTCTG------CTLCLSVCP--------------------IVDCIKMVSRTTPYEPKRGVPLSVNPVC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYG8-1", "uniprot_id": "DPYD_DANRE", "id": "Q6NYG8-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAT--MLSKELQDIESILA----------------------------------------------------------------LNPRVKSHANVHSTASKKNEKKHWKRNP-----------------------ERSCDSCVNLENNFDDIKHTT----------------LSERGALREALRCLKCADAPCQKSCPTNLDIKSFITSISNKNYYGAAKAILSDNPLG---------------LTCG--MVCPTSDLCVGGCNLYASEEGPINIGGLQQFATEVFSKMGIPQIRNPE-----------------------------------------LPTADNMPKSFHTRIALIGCGPASISCASFLARLG---------------------------------YDNITIFEKQKYIGG---------------------------LSTSEIPQFRLPYEVVQFEIDLMKDLGVK------------------------VVLEKGLGQNGLTLTSLKEE----------------------------GYQVVYIGIGLP------------QANRDKIFEGLTTEQGFYTSKDFLPLVAKASKIGMCNCRSQ-----LPKLHGNVIVLGAG------DTAFDCATSALR-----CGARRVFVVFRKGFTNIRAVPEEMEAAKEEKCEFLP-----------FLSPHEVIKKNGRVSGLRFCRTEQQDDGTWIVDEEQIVHLKADFIIS-------------------AFGSMLNDPAVTKALDPIKLNRWGTP------------EVNSETMQTTEPWVFAG---------GDIAGFANTTVESVNDGKQASWHIHKYIQSLHGNTISATPR----LPLFHCSIDTVDISVEMCGIKFPNPFG--------------LASAPPTTSAAMIRRAFEQG----------------WGFALTKTFG------LDKDLVTNVSPRIVR--GTTSGHIFGPGQGSFLNIELISE-----------------------------KTAAYWCKSVAELKADFPKNIIIASIMCSYNQADWTELAKMAQESQADALELNLS---CPHGMGERGMG--LACGQDPELVRNICRWVRKATSIPFFAKLTPNVTNIVD----------IATAAYEGGADGVTATNTVSGLMA-----------------LKADATPWPGIGR-----------------------GARTTYGGVSGNAIRPIALRAVSAIARALPGFPILATGG-------------IDSAESGLQFLHAGASVLQVCSAVQNQDFT--------VIEDYCLGLKALLYLKSIEELHD---WDGQS---------------------PPTIRHQKGKPVPHVSELIGKSLPSFGPYLQTKTQALAKYKKD--ASG-DVIMDTGAARVNIPKKP-IPNVKDVIARALKHIGAYQELDNTE------------------------------QVQALVDPEMCINCGKCYMTCND--------SGYQAIKFDPETHLPVITDSCTG------CTLCLSVCP--------------------IIDCIKMVSRTTPYEPKRGLP--VNPVC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W374-1", "uniprot_id": "Q9W374_DROME", "id": "Q9W374-1", "name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPPQLLSKDSPDIEDLLS----------------------------------------------------------------LNPRVKTQCSVVPTKQTKENKKHWKRNA-----------------------DHAAPPCTTLANDFSDIKHTT----------------LSERGALEEAARCLKCADAPCQKSCPTQLDIKSFITSIANKNFYGAAKAIFSDNPLG---------------LTCG--MVCPTSDLCVGGCNLQASEAGPINIGGLQQFATEVFKKMGVRQRRTP----------------------------------------------QAEANPLSQKIALVGGGPASLSCATFLARLG---------------------------------YRDVTIYERRSYLGG---------------------------LSAAEIPQYRLPIDAVNFEIDLVRDLGVR------------------------IETGRSLGTKDLTIQGLLST----------------------------GHDAVFVGIGLP------------EPKLNPIFAGLQPSNGFYTSKNFLPLVSDGSKPGLCACKAAA---GLPKLHGNVIVLGAG------DTAFDCATSALR-----CGARRVFVVFRKGSSGIRAVPEEVELARDERCELLP-----------YLSPRKVIVKDGLITAMEFCRTEQNENDEWVEDEEQTQRLKANFVIS-------------------AFGSGLEDQDVKAALAPLQF-RGELP------------VVDRVTMQSSVKQVFLG---------GDLAGVANTTVESVNDGKVAAWSIHCQLQGLP---LDTPAA----LPLFYTDIDAVDISVEMCGIRFENPFG--------------LASAPPTTSTAMIRRAFEQG----------------WGFVVTKTFG------LDKDLVTNVSPRIVR--GTTSGYKYGPQQGCFLNIELISE-----------------------------KRAEYWLKSIGELKRDFPEKIVIASIMCSFNEEDWTELAIKAEQSGADALELNLS---CPHGMGERGMG--LACGQDPELVEQISRWVRKAVKLPFFIKLTPNITDIVS----------IAAAAKRGGADGGSAINTVQGLMG-----------------LKADSTAWPAIGK-----------------------EQRTTYGGVSGNATRPMALKAISDIANRVPGFPILGIGG-------------IDSGEVALQFIHAGATVLQICSSVQNQDFT--------VIEDYCTALKALLYLKANPPPVDGPFWDGQS---------------------PPTPVHQKGKPVVRLTGEGKATLGFFGPYQRQRDIKMAELRSQKGALWDAEQVKATPPASNGAPNP-APRIKDVIGAALDKIGSYNKLDNKQ------------------------------QKVALIDDDMCINCGKCYMTCAD--------SGYQAIEFDKDTHIPHVNDDCTG------CTLCVSVCP--------------------IIDCITMVPKKIPHVIKRGVEEKIFYTHALSQCQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12680-1", "uniprot_id": "GLT1_YEAST", "id": "Q12680-1", "name": "Glutamate synthase [NADH]", "aln": "MPVLKSDNFDPLEEAYEGGTIQNYNDEHHLHKSWANVIPDKRGLYDPDYEHDACGVGFVANKHGEQSHKIVTDARYLLVNMTHRGAVSSDGNGDGAGILLGIPHEFMKREFKLDLDLDIPEMGKYAVGNVFFKKNEKNNKKNLIKCQKIFEDLAASFNLSVLGWRNVPVDSTILGDVALSREPTILQPLLVPLYDEKQPEFNETKFRTQLYLLRKEASLQIGLENWFYVCSLNNTTIVYKGQLTPAQVYNYYPDLTNAHFKSHMALVHSRFSTNTFPSWDRAQPLRWLAHNGEINTLRGNKNWMRSREGVMNSATFKDELDKLYPIIEEGGSDSAALDNVLELLTINGTLSLPEAVMMMVPEAYHKDMDSDLKAWYDWAACLMEPWDGPALLTFTDGRYCGAILDRNGLRPCRYYITSDDRVICASEVGVIPIENSLVVQKGKLKPGDLFLVDTQLGEMVDTKKLKSQISKRQDFKSWLSKVIKLDDLLSKTANLVPKEFISQDSLSLKVQSDPRLLANGYTFEQVTFLLTPMALTGKEALGSMGNDAPLACLNENPVLLYDYFRQLFAQVTNPPIDPIREANVMSLECYVGPQGNLLEMHSSQCDRLLLKSPILHWNEFQALKNIEAAYPSWSVAEIDITFDKSEGLLGYTDTIDKITKLASEAIDDGKKILIITDRKMGANRVSISSLIAISCIHHHLIRNKQRSQVALILETGEAREIHHFCVLLGYGCDGVYPYLAMETLVRMNREGLLRNVNNDNDTLEEGQILENYKHAIDAGILKVMSKMGISTLASYKGAQIFEALGLDNSIVDLCFTGTSSRIRGVTFEYLAQDAFSLHERGYPSRQTISKSVNLPESGEYHFRDGGYKHVNEPTAIASLQDTVRNKNDVSWQLYVKKEMEAIRDCTLRGLLELDFENSVSIPLEQVEPWTEIARRFASGAMSYGSISMEAHSTLAIAMNRLGAKSNCGEGGEDAERSAVQENGDTMRSAIKQVASARFGVTSYYLSDADEIQIKIAQGAKPGEGGELPAHKVSKDIAKTRHSTPNVGLISPPPHHDIYSIEDLKQLIYDLKCANPRAGISVKLVSEVGVGIVASGVAKAKADHILVSGHDGGTGAARWTSVKYAGLPWELGLAETHQTLVLNDLRRNVVVQTDGQLRTGFDIAVAVLLGAESFTLATVPLIAMGCVMLRRCHLNSCAVGIATQDPYLRSKFKGQPEHVINFFYYLIQDLRQIMAKLGFRTIDEMVGHSEKLKKRDDVNAKAINIDLSPILTPAHVIRPGVPTKFTKKQDHKLHTRLDNKLIDEAEVTLDRGLPVNIDASIINTDRALGSTLSYRVSKKFGEDGLPKDTVVVNIEGSAGQSFGAFLASGITFILNGDANDYVGKGLSGGIIVIKPPKDSKFKSDENVIVGNTCFYGATSGTAFISGSAGERFGVRNSGATIVVERIKGNNAFEYMTGGRAIVLSQMESLNAFSGATGGIAYCLTSDYDDFVGKINKDTVELESLCDPVEIAFVKNLIQEHWNYTQSDLAARILGNFNHYLKDFVKVIPTDYKKVLLKEKAEAAKAKAKATSEYLKKFRSNQEVDDEVNTLLIANQKAKEQEKKKSITISNKATLKEPKVVDLEDAVPDSKQLEKNSERIEKTRGFMIHKRRHETHRDPRTRVNDWKEFTNPITKKDAKYQTARCMDCGTPFCLSDTGCPLSNIIPKFNELLFKNQWKLALDKLLETNNFPEFTGRVCPAPCEGACTLGIIEDPVGIKSVERIIIDNAFKEGWIKPCPPSTRTGFTVGVIGSGPAGLACADMLNRAGHTVTVYERSDRCGGLLMYGIPNMKLDKAIVQRRIDLLSAEGIDFVTNTEIGKTISMDELKNKHNAVVYAIGSTIPRDLPIKGRELKNIDFAMQLLESNTKALLNKDLEIIREKIQGKKVIVVGGGDTGNDCLGTSVRHGAASVLNFELLPEPPVERAKDNPWPQWPRVMRVDYGHAEVKEHYGRDPREYCILSKEFIGNDEGEVTAIRTVRVEWKKSQSGVWQMVEIPNSEEIFEADIILLSMGFVGPELINGNDNEVKKTRRGTIATLDDSSYSIDGGKTFACGDCRRGQSLIVWAIQEGRKCAASVDKFLMDGTTYLPSNGGIVQRDYKLLKELASQV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **:: :: :* *.: ::: : : .. *.* . . .: .::..: * .*:* . : . . :*. :.*. :: : : *.* ::*. :*.. ::*.:. : * . : * :: *.* . *:: . :. : :. .: . . . * ::: *. :* : .: . . *:* : :* . ...:::* : :. *: : : :. . ::: * : . :* * . : : :: .: :. . ::* .. . *: : *.. :* *. . * * .* ::* :* * .* :..:* . :::.:.:: ... . .: * :..: : . : : :.* : :: .. *. .:** : *: :: : **::: * . .* . . .:..: *: . * : : * .: . *:. : .:: ** . :**. . :.: * : . * * : :::*. * :::*.:.. :: . : . *. . : .: **: . : : . * *: . : .: : . * : *.*::::** * : . *: :: ** :* .: . : . . :.: *. *: : .: . * :* . ..* .: . *:.*.. : . * **..**.: . : : . . : : * : * .*: : ..: : * : : :**. :*. * :: : : : * : ::*.:.. : * * . . : . .* ::*.: : . .:. . : * : *::**. : . . :: : *. : ::. . *. :* : * *:* * . : ", "identical_positions": 121, "similar_positions": 361, "identity": "5.64%" }, { "cls_id": "homologset.agr.RGD:621219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51791-1", "uniprot_id": "CLCN3_MOUSE", "id": "P51791-1", "name": "H(+)/Cl(-) exchange transporter 3", "aln": "--------------------------MESEQLFHRGYYRNS-----------------YNSITSASSDEE-------------LLDGAGAIMDFQTSEDDNLLDGDTAAGTHYTMTNGGS-----------INSSTHLLDLLD------------EPIPGVGTYDDFHTIDWVREKCKDRERHRRINSKKKESAWEMTKSLYDAWSGWLVVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIR-GYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVS--YYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESS-SLCDYRNDMNASKIVDDIPDRP--AGVGVYSAIWQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREG-IYEAHIRLNGYPFLDAKEEFTHTTLAADVMRPRRSDPPLAVLTQDNMTVDDIENMINETS----YNGFPVIMSKE----SQRLVGFALRRDLTIAIESARKKQEGIVGSSRVCFAQHTPSLPAESPRPLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGIVLGIITKKDILRHMAQTANQ----------------------------------DPASIMFN----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51792-1", "uniprot_id": "CLCN3_RAT", "id": "P51792-1", "name": "H(+)/Cl(-) exchange transporter 3", "aln": "--------------------------MESEQLFHRGYYRNS-----------------YNSITSASSDEE-------------LLDGAGAIMDFQTSEDDNLLDGDTAAGTHYTMTNGGS-----------INSSTHLLDLLD------------EPIPGVGTYDDFHTIDWVREKCKDRERHRRINSKKKESAWEMTKSLYDAWSGWLVVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIR-GYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVS--YYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESS-SLCDYRNDMNASKIVDDIPDRP--AGVGVYSAIWQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREG-IYEAHIRLNGYPFLDAKEEFTHTTLAADVMRPRRSDPPLAVLTQDNMTVDDIENMINETS----YNGFPVIMSKE----SQRLVGFALRRDLTIAIESARKKQEGVVGSSRVCFAQHTPSLPAESPRPLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDILRHMAQTANQ----------------------------------DPASIMFN----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51790-1", "uniprot_id": "CLCN3_HUMAN", "id": "P51790-1", "name": "H(+)/Cl(-) exchange transporter 3", "aln": "--------------------------MESEQLFHRGYYRNS-----------------YNSITSASSDEE-------------LLDGAGVIMDFQTSEDDNLLDGDTAVGTHYTMTNGGS-----------INSSTHLLDLLD------------EPIPGVGTYDDFHTIDWVREKCKDRERHRRINSKKKESAWEMTKSLYDAWSGWLVVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIR-GYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVS--YYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESS-SLCDYRNDMNASKIVDDIPDRP--AGIGVYSAIWQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREG-IYEAHIRLNGYPFLDAKEEFTHTTLAADVMRPRRNDPPLAVLTQDNMTVDDIENMINETS----YNGFPVIMSKE----SQRLVGFALRRDLTIAIESARKKQEGIVGSSRVCFAQHTPSLPAESPRPLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDILRHMAQTANQ----------------------------------DPASIMFN----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q887-1", "uniprot_id": "A0A8M9Q887_DANRE", "id": "A0A8M9Q887-1", "name": "Chloride channel protein", "aln": "--------------------------MESEQLFNRGYGRNS-----------------YNSITSASSDEE-------------LLDGAGVIMDFHTTEDDNLLDGDASPGSNYAMSNGGGGGG-------GASSSTHLLDLLE------------EPIPGVGTYDDFHTIDWVREKCKDRERHRKINSKKKESAWEFTKSLYDAWSGWLVVTLTGLASGALAGGIDIAADWMNDLKEGVCLSAMWFNHEQCCWGSNKTTFAERDKCPQWKTWAELILGQEQGPGSYIMNYFMFTFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIR-GYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYSKNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVS--YYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTRFGKYPVLEVITVAAITAIVAFPNPYTRQNTSELIKELFTDCGPLESS-QLCQYRSLMNGSQADPTGPDTASAATPGVYSAMWQLSLALVFKIIMTIFTFGLKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFVFREWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREG-IYEAHIRLNGYPFLDAKEEFTHTTLAREVMRPRRSDPPLAVLTQDDMTLAELQGIISETS----YNGFPVIVSKE----SQRLVGFALRRDITIAIENARRKQEGIVLNSRVYFTQHAPTLPADSPRPLKLRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGIVLGIITKKNILEHLEEIKQHVEPLTPPWYYYKKRYPPSYGPDGKPRPRVHNVQLAPSSSHYQEDEIEEEVRLLDNSSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUY1-1", "uniprot_id": "Q9VUY1_DROME", "id": "Q9VUY1-1", "name": "Chloride channel protein", "aln": "MEKFPLKGSREAAAEGNSYITAYQTVMKKSNGHTNGAGGDGDLDGTFRDHPLAQHTKLTTSLTAAGTDDEDMIDITPRSSPGDVIGGGGGGGSSSGYHRETATESDTERDFGHSGGNGGGNHHNQRTMHQHVPTHSAFGDPMDGALSFYGSSDVQDDIPGIGQYEDFHTIDWQRDIARDRMRHRYIVKKRQDSLWDLIKGSIDAGSGWLCVLLVGIAAGCVAGMVDIGASWMSDLKHGICPPAFWFNREQCCYPAKQSVFEEGN-CSTWKTWPEIFGLDRNGTGPYIVAYIWYVLWALLFASLSASLVRMFAPYACGSGIPEIKTILSGFIIR-GYLGKWTLLIKSVGLMLSVSAGLTLGKEGPMVHIASCIGNIFSHVFPKYGRNEAKKREILSAAAAAGVSVAFGAPIGGVLFSLEEVS--YYFPLKTLWRSFFCALIAAFVLRSLTPFGNEHSVLFFVEYNKPWIFFELIPFVFLGIMGGVIGTFFIKANLWWCRYRKFSKLGQYPVMEVLFVTLVTAIICYPNPFTRMNMNELIFLLVSKCSPGDVTNPLCDYKR-MNITSGNSFIEVTE--PGPGVYSSIWLLMLTFILKLALTIFTFGMKVPAGLFIPSLLLGAIMGRIVGIGVEQFAYSYPNIWFFTGECAD-SNLITPGLYAVVGAAAVLGGVTRMTVSLVVIMFELTGGVRYIVPLMAAAMASKWVGDALGRQG-IYDAHIALNGYPFLDSKEEFAHTTLAADVMQPKRNE-TLNVITQDSMTVDDVENLLKETE----HNGYPVVVSRE----NQYLVGFVLRRDLNLAIGNAKRLIEGISSSSIVLFTSSQP-IQNLGPQPLKLKKILDMAPITVTDQTPMETVVDMFRKLGLRQTLVTHNGRLLGVITKKDVLRHVKQMDNE----------------------------------DPNTVLFN----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P37020-1", "uniprot_id": "GEF1_YEAST", "id": "P37020-1", "name": "Anion/proton exchange transporter GEF1", "aln": "------------------------------------------------------------------------------------------MPTTYVPINQPIGDGEDVIDTNRFTN-----------------------------------------IPETQNFDQFVTIDKIAEENRPLSVDSDREFLN-SKYRHYREVIWDRAKTFITLSSTAIVIGCIAGFLQVFTETLVNWKTGHCQRNWLLNKSFCCNGVVNEVTSTSNLLLKRQEFECEAQGLWIAWKGHVSPFIIFMLLSVLFALISTLLVKYVAPMATGSGISEIKVWVSGFEYNKEFLGFLTLVIKSVALPLAISSGLSVGKEGPSVHYATCCGYLLTKWLLRDTLTYSSQYEYITAASGAGVAVAFGAPIGGVLFGLEEIASANRFNSSTLWKSYYVALVAITTLKYIDPFRNGRVILFNVTYDRDWKVQEIPIFIALGIFGGLYGKYISKWNINFIHFRK-MYLSSWPVQEVLFLATLTALISYFNEFLKLDMTESMGILFHECVKNDNTSTFSHRLCQLDENT-----------HAFEFLKIFTSLCFATVIRALLVVVSYGARVPAGIFVPSMAVGATFGRAVSLLVERFIS--------------GPSVITPGAYAFLGAAATLSGITNLTLTVVVIMFELTGAFMYIIPLMIVVAITRIILSTSGISGGIADQMIMVNGFPYLEDEQDEEEEETLEKYTAEQLMSSKLITIN-ETIYLSELESLLYDSASEYSVHGFPITKDEDKFEKEKRCIGYVLKRHLASKIMMQS--VNSTKAQTTLVYFNKSNEELGHRENCIGFKDIMNESPISVKKAVPVTLLFRMFKELGCKTIIVEESGILKGLVTAKDILRFKRIKYREVHG----------------------AKFTYNEALDRRCWSVIHFIIKRFTTNRNGNVI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.: . ** :::* *** : : . . .. . : * . :: : ..:. *.:** ::: :. : : * * * *:. ** : . : : : . :: :: : : :: ** ::. **: .** * ****.***. :*** . :** **:**:: * *::::**::***** ** * * * ::: : : . :.: * ::**:.***:************.***:: * .***:*:: **:* .*: : ** * : :** * *. * . *: *: **::**: * :: : *: : : ** :..:** **: :: :**::.: * : : : .* : *. .* : : :.. :: . . . : * :: ::: :.:.::* :**:*:*:**: :** ** *.: **:: .. **** **.:**** *.*:*.:*:::***:*****.. **:*** .. :: : .: * .* * : * :**:*:*: ::: . . : . * .:. : : : :::.:: :: :*:*: ..: .: :*:.*:*.: * :. .: : : . . : ::.*:: :*::*.. .*: :. :*::** : :* ..* : *::* *::*.. .. ", "identical_positions": 181, "similar_positions": 261, "identity": "18.81%" }, { "cls_id": "homologset.agr.RGD:621220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62975-1", "uniprot_id": "ZPI_RAT", "id": "Q62975-1", "name": "Protein Z-dependent protease inhibitor", "aln": "---MRVVSSLFLPVLLAEVWLVSSFNLSSHSPEAPIRLVSQDYENQTWEEYEWADPRD--------------------------DNEYWLRAS-QQLSNETSSFGFSLLRKIS----------MRHDGN---VIFSPFGLSVAMVNLMLGAKGETKVQVENGLNLQALS---QAGPLILPALFKRVKETFSS---------------------NKKLGLTQGSFAFIHKDFEIKKTYFNLSTMYFDTEYVPTNFR-NSSQARGLMNHYINKETEGKIP-KLFDEINPETKLILVDYILFKGKWLTPFDPIFTEADTFHL--DKYKAV-KVPMMYREGNFASTFDKK-FRCHILKLPY--QGNATMLVVLM---EKSGDHLALEDYLTTDLVEMWLQDMKTRK--------MEVFFPKFKLNQRYEMHELLKQVGIRRIFS----------------------------TSADLSELSAVARNLQVSKVVQQSVLEVDERGTEVVSGTVSEITAYCMPPVIKVDRPFHFIIYEEMSQMLLFLGRVVNPTVL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R121-1", "uniprot_id": "ZPI_MOUSE", "id": "Q8R121-1", "name": "Protein Z-dependent protease inhibitor", "aln": "---MRVASSLFLPVLLTEVWLVTSFNLSSHSPEASVHLESQDYENQTWEEYTRTDPREEEEEEEEKEE--------------GKDEEYWLRAS-QQLSNETSSFGFNLLRKIS----------MRHDGN---VIFSPFGLSVAMVNLMLGTKGETKVQIENGLNLQALS---QAGPLILPALFKKVKETFSS---------------------NRDLGLSQGSFAFIHKDFDIKETYFNLSKKYFDIEYVSINFQ-NSSQARGLINHCIVKETEGKIP-KLFDEINPETKLILVDYVLFKGKWLTPFDPSFTEADTFHL--DKYRAI-KVPMMYREGNFTSTFDKK-FRCHILKLPY--QGNATMLVVLM---EKTGDYLALEDYLTVDLVETWLQNMKTRK--------MEVFFPKFKLNQRYEMHELLKQMGIRRLFS----------------------------TSADLSELSAMARNLQVSRVLQQSVLEVDERGTEAVSGTLSEIIAYSMPPAIKVNRPFHFIIYEEMSRMLLFLGRVVNPTVL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK55-1", "uniprot_id": "ZPI_HUMAN", "id": "Q9UK55-1", "name": "Protein Z-dependent protease inhibitor", "aln": "---MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASE-------------------EEKAWLMASRQQLAKETSNFGFSLLRKIS----------MRHDGN---MVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALK---PTKPGLLPSLFKGLRETLSR---------------------NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFR-NASQAKRLMNHYINKETRGKIP-KLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHL--DKYKTI-KVPMMYGAGKFASTFDKN-FRCHVLKLPY--QGNATMLVVLM---EKMGDHLALEDYLTTDLVETWLRNMKTRN--------MEVFFPKFKLDQKYEMHELLRQMGIRRIFS----------------------------PFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AK66-1", "uniprot_id": "A0A8M3AK66_DANRE", "id": "A0A8M3AK66-1", "name": "", "aln": "------MEFRLLLVFISACFLCSAEHEELRTPDIS------------------------------------------------------------DLAFRNTDFAINLYRKIS----------SLHDRN---VVFSPLSVSTCFSALLLAAQGSTRTEILKGLNLEALD---GGDSRRVPELFQQLHQNIS-------------------------LQMEQGTALFLDQHFHLQTNFSQQIQRFFNAEVLRVDFS-KPAVCRSLINEFVSRKTGRKVL-EMLESVEPLTQMMLLNTIFYKGDWERPFNPNNTEKSRFYV--DKYNIV-QVPMMMLEEKFSVVEDRD-LRARVLRLPY--RGGASMLILLP---NADADYTAIEDEISAERLHGWIKNMRRMK--------MEVHLPRFRMDQSYHMHELLPQLGISSVFQ----------------------------DSADLTGLSRDAH-LKVSQVLHKAVIEVYEQGTSAASSTSVGITAYSLPDTFIINRPFFFFLYHEETASLLFMGRVIDPTLS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E8C8-1", "uniprot_id": "SP77B_DROME", "id": "Q0E8C8-1", "name": "Serine protease inhibitor 77Ba", "aln": "MGKIADCLMLWIPLLLGAIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQS-------------------------MRSNFDTDVLVSISQGVQDFALDLLQRIS----------VEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVED---EKLRGAYKVWSSFLNITTS------------------------TIEVATLQAIYTGKGYPIKNNYRDAIQN-YNVQPMEVDFY-SPD-SVIQINEDTNRTTRGLIPYTILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFS--ESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLP---KRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFD----------------------------ENT--ANLDRMSSGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLLNRPFQYMIVEKATGLLLFAGQVRNPKAA-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLU4-1", "uniprot_id": "SP28D_DROME", "id": "Q9VLU4-1", "name": "Serine protease inhibitor 28Dc", "aln": "----MWRLLLALLLVSSVCCESELFRDDLRTPETMAYINGLMQRRHQMQQEAQQHIQAIPPAVPLQSPGLVNGLGNQNDPALNRISGTSVKPSNLPAAYSNGYVDLATSDRIANSVLNFANILGQHLANGKTQIYSPLSIVHSLALLLLGAKGRSYEELSTVFDIPDTSRLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTLNPDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASDIPQTTRMILANALYFKAFWETDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHEDHE-LGCKIIGLPY--RGNLSTMYIIQPFKSSVRELMALQKRLTADKIESMISRMYRRA--------ALVAFPKMHLTESVNLKTVMQRMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTEAAASSVTYLKKSGPDVLFRGDTPFMVLVRHDPTKLVLFYGLINEPPAAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. . ::* : . : :*: : **:.: : * .: * : :: : : . . . * : : : :: : : : :* .. . :* : * : : . ::::* . : :*. * * *. . *. : . : :: ** :. : . : :: *** :. : : :: . . : . :.. :. : : * :*:: :: :: ::*: :*. : . * .. ::: : * *:** . : : : : ** :: .. : :** * : :* ", "identical_positions": 36, "similar_positions": 117, "identity": "6.53%" }, { "cls_id": "homologset.agr.RGD:621221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70165-1", "uniprot_id": "FCN1_MOUSE", "id": "O70165-1", "name": "Ficolin-1", "aln": "MQWPTLWAFSGLLCLCPSQALGQERGACPDVKVVGLGAQDKVVVIQSCPGFPGPPGPKGEPGSPAGRGERGFQGSPGKMGPAGSKGEPGTMGPPGVKGEKGDTGAAPSLGEKELGDTLCQRGPRSCKDLLTRGIFLTGWYTIHLPDCRPLTVLCDMDVDGGGWTVFQRRVDGSIDFFRDWDSYKRGFGNLGTEFWLGNDYLHLLTANGNQELRVDLQDFQGKGSYAKYSSFQVSEEQEKYKLTLGQFLEGTAGDSLTKHNNMSFTTHDQDNDAN-SMNCAALFHGAWWYHNCHQSNLNGRYLSGSHESYAD--GINWGTGQGHHYSYKVAEMKIRAS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WTS8-1", "uniprot_id": "FCN1_RAT", "id": "Q9WTS8-1", "name": "Ficolin-1", "aln": "MWWPMLWAFPVLLCLCSSQALGQESGACPDVKIVGLGAQDKVAVIQSCPSFPGPPGPKGEPGSPAGRGERGLQGSPGKMGPPGSKGEPGTMGPPGVKGEKGERGTASPLGQKELGDALCRRGPRSCKDLLTRGIFLTGWYTIYLPDCRPLTVLCDMDVDGGGWTVFQRRVDGSINFYRDWDSYKRGFGNLGTEFWLGNDYLHLLTANGNQELRVDLREFQGQTSFAKYSSFQVSGEQEKYKLTLGQFLEGTAGDSLTKHNNMAFSTHDQDNDTNGGKNCAALFHGAWWYHDCHQSNLNGRYLPGSHESYAD--GINWLSGRGHRYSYKVAEMKIRAS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VME7-1", "uniprot_id": "Q9VME7_DROME", "id": "Q9VME7-1", "name": "Fibrinogen C-terminal domain-containing protein", "aln": "--MRSVWIYVAFLGLSFYSTEAMDSESFQNDTAIRNKPELKSLYKLVLALLEE---------NQSNASTENIQKSSSDLNTTGLSG----------------------------------RYPSQCPTYPP----AHGIYTVQVLGLKPFQVSCDAEIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTRYAHYDEIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGW-HKNCAEEYVGAWWHLNCTYSNLFGIYVKGDEGQYFQWKGIVWHSWRTESYSYKVMQMMVRPKCHCSG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : :* *. .: . : : : . : .: * . : . :. . ..:* *...:...* .* * * .* . * **: : . :*: * ** :: * ****: **....::*:*.* .**.***:*. :*::* * ** :* . :** :.*.:*:*: :*:*..: :. *:: * :* : * ****: ::.* *:*.*:*** *** : ****: :* *** * *: *.. .* : ** * : : . ***** :* :*.. ", "identical_positions": 87, "similar_positions": 98, "identity": "25.44%" }, { "cls_id": "homologset.agr.RGD:621222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15485-1", "uniprot_id": "FCN2_HUMAN", "id": "Q15485-1", "name": "Ficolin-2", "aln": "MELDRAVGVLGAATLLLSFLGMA-WALQAADTCPEVKMVGLEGSDKLTILRGCPGLPGAPGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGE------------PQPCLTGPRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFAN--GINWKSGKGYNYSYKVSEMKVRPA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O00602-1", "uniprot_id": "FCN1_HUMAN", "id": "O00602-1", "name": "Ficolin-1", "aln": "MELSGATMARGLAVLLVLFLHIKNLPAQAADTCPEVKVVGLEGSDKLTILRGCPGLPGAPGPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYAN--GINWSAAKGYKYSYKVSEMKVRPA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P57756-1", "uniprot_id": "FCN2_RAT", "id": "P57756-1", "name": "Ficolin-2", "aln": "-------MVLGSAALFVLSLCVTELTLHAADTCPEVKVLDLEGSNKLTILQGCPGLPGALGPKGEAGAKGDRGESGLPGHPGKAGPTGPKGDRGEKGVRGEKGDTGPSQSCATGPRTCKELLTRGYFLTGWYTIYLPDCRPLTVLCDMDTDGGGWTVFQRRIDGTVDFFRDWTSYKQGFGSQLGEFWLGNDNIHALTTQGTNELRVDLADFDGNHDFAKYSSFQIQGEAEKYKLILGNFLGGGAGDSLTSQNNMLFSTKDQDNDQGSSNCAVRYHGAWWYSDCHTSNLNGLYLRGLHKSYAN--GVNWKSWKGYNYSYKVSEMKVRLI-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70497-1", "uniprot_id": "FCN2_MOUSE", "id": "O70497-1", "name": "Ficolin-2", "aln": "-------MALGSAALFVLT-----LTVHAAGTCPELKVLDLEGYKQLTILQGCPGLPGAAGPKGEAGAKGDRGESGLPGIPGKEGPTGPKGNQGEKGIRGEKGDSGPSQSCATGPRTCKELLTQGHFLTGWYTIYLPDCRPLTVLCDMDTDGGGWTVFQRRLDGSVDFFRDWTSYKRGFGSQLGEFWLGNDNIHALTTQGTSELRVDLSDFEGKHDFAKYSSFQIQGEAEKYKLILGNFLGGGAGDSLTPHNNRLFSTKDQDNDGSTSSCAMGYHGAWWYSQCHTSNLNGLYLRGPHKSYAN--GVNWKSWRGYNYSCKVSEMKVRLI-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VME7-1", "uniprot_id": "Q9VME7_DROME", "id": "Q9VME7-1", "name": "Fibrinogen C-terminal domain-containing protein", "aln": "---------MRSVWIYVAFLGLSFYSTEAMDSESFQNDTAIRNKPELKSLY---KLVLALLEENQSNASTEN----IQKSSSDLNTTGLSG--------------RYPSQCPTYPP-----------AHGIYTVQVLGLKPFQVSCDAEIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTRYAHYDEIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEYVGAWWHLNCTYSNLFGIYVKGDEGQYFQWKGIVWHSWRTESYSYKVMQMMVRPKCHCSG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . .* .: . : :.. :*. * * * :.::.. .. ... .. * .* .. * * * * :*: : . :*: * ** : * ****: ** ...::*:*.*: **.***. *:*::* *::**:* . . ** :.* **:.: :*:* .: : .* : * : . *.**:*: :.* *** *:*** .** : ****: :* *** * *: * . .: : *: * : : .** ** :* ** ", "identical_positions": 81, "similar_positions": 90, "identity": "24.32%" }, { "cls_id": "homologset.agr.RGD:621223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62674-1", "uniprot_id": "S28A1_RAT", "id": "Q62674-1", "name": "Sodium/nucleoside cotransporter 1", "aln": "MADNTQRQRESISLTPMAHGLENMGAEFLESMEEGRLPHSHSSLPEGEGGLNKAERKAFSRW-RSLQPTVQARSFCREHRQLFGWICKGLLSTACLGFLMVACLLDLQRALALLIITCVVLVFLAYDLLKRLLGSKLRRCVK----FQGHSCLSLWLKR-GLALAAGVGLILWLSLDTAQRPEQLVSFAGICVFLVLLFAGSKHHRAVSWRAVSWGLGLQFVLGLFVIRTEPGFIAFQWLGDQIQVFLSYTEAGSSFVFGEALVKD-VFAFQVLPIIIFFSCVMSVLYYLGLMQWVILKIAWLMQVTMGTSATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFRSENGVKLTYGDAQNLLEAASAGAAISVKVVANIAANLIAFLAVLAFVNAALSWLGDMVDIQGLSFQLICSYVLRPVAFLMGVAWEDCPVVAELLGIKFFLNEFVAYQELSQYKQRRLAGAEEWLGDKKQWISVRAEILTTYALCGFANFSSIGIMLGGLTSLVPQRRSDFSQIVLRALITGAFVSLLNACVAGILYVPRGVEVDCVSLLN-QTVSSSSFEVYLCCRQVFQSTS-------------SEFSQVALDNCCRFYNHTVCT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PXX9-1", "uniprot_id": "S28A1_MOUSE", "id": "E9PXX9-1", "name": "Sodium/nucleoside cotransporter 1", "aln": "MADDTPRQRESISLTPVAHGLENMGAEFLEIMEEGQLPHRHSSLPEGGGSRSKAVWKPFSRW-RSLQPTVQARSLCREHWQLFEWISKGLLSTAYIGFLIVACLLDFPRALALFVITCVVLVFLAYNLLKRLLGSKLKKCVK----FQGHSCLSLWLKR-GLALAAGLGVILWLSLDTAQRPEQLVSFAGICVFLVLLFAGSKHHRAVSWRAVSWGLGLQFVLGLFVIRTEPGFVAFQWLGDQIRVFLSYTEAGSSFVFGEALVKD-VFAFQVLPIIVFFSCVMSVLYYLGLMQWVILKIAWLMQVTMGTSATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDASSLIAASVMAAPCALALSKLVYPEVEESKFRSEEGVKLTYGDAQNLVEAASAGAAISVKVVANIAANLIAFLAVLAFINAALSWLGDMVDIQGLSFQLICSYVLRPVAFLMGVAWEDCPVVAELLGIKLFLNEFVAYQELSQYKQRRLAGAEEWLGDKKQWISVRAEILTTYALCGFANFSSIGIMLGGLTSMVPQRRSDFSQIVLRALITGAFVSLVNACVAGILYVPRGVEVDCMSLLN-QTVSSSSFEVYLCCRQVFQNTS-------------LEFGQEALHNCCRFYNHTVCT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00337-1", "uniprot_id": "S28A1_HUMAN", "id": "O00337-1", "name": "Sodium/nucleoside cotransporter 1", "aln": "MENDPSRRRESISLTPVAKGLENMGADFLESLEEGQLPRSDLSPAEIRSSWSEAAPKPFSRW-RNLQPALRARSFCREHMQLFRWIGTGLLCTGLSAFLLVACLLDFQRALALFVLTCVVLTFLGHRLLKRLLGPKLRRFLK----PQGHPRLLLWFKR-GLALAAFLGLVLWLSLDTSQRPEQLVSFAGICVFVALLFACSKHHCAVSWRAVSWGLGLQFVLGLLVIRTEPGFIAFEWLGEQIRIFLSYTKAGSSFVFGEALVKD-VFAFQVLPIIVFFSCVISVLYHVGLMQWVILKIAWLMQVTMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDATSLIAASVMAAPCALALSKLVYPEVEESKFRREEGVKLTYGDAQNLIEAASTGAAISVKVVANIAANLIAFLAVLDFINAALSWLGDMVDIQGLSFQLICSYILRPVAFLMGVAWEDCPVVAELLGIKLFLNEFVAYQDLSKYKQRRLAGAEEWVGDRKQWISVRAEVLTTFALCGFANFSSIGIMLGGLTSMVPQRKSDFSQIVLRALFTGACVSLVNACMAGILYMPRGAEVDCMSLLN-TTLSSSSFEIYQCCREAFQSVN-------------PEFSPEALDNCCRFYNHTICAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HUD0-1", "uniprot_id": "A0AC58HUD0_DANRE", "id": "A0AC58HUD0-1", "name": "Sodium/nucleoside cotransporter", "aln": "MLED----KEDLQLTDVSYGNE-QGVDNPVFVKEDTLPDDLSDSDKESEKDSKSEKESSSCMSKACLPITVTETFFKTHSKIIKYIVLAILAAGYLAYFIYACYLSFQRALALVVLTCLGVFILVCELVFRYKGDSIKRCFKP--VQRCFRSNMKWMKW-VFIVIVVGLLVAWLAVDTRKRPEQLISFGGVCLFIVAIFLFSAHRTAVRWSTVFWGLGLQFAIGLFVIRTEPGLVAFEWLGKQVQIFLDYTKAGSGFVFGN-LIDN-IFAFQALPIVVFFSSVMSVLYYLGVMQWVITKISWVMQVTMGTSSTETLSVAGNIFVGQTEAPLLIRPYLKDMTKSEIHAVMTGGFATIAGSVMGAFISFGIDASSLISASVMAAPCALAISKLSYPETEKSKFTSKSQIKVDSGGEQNVLEAVSGGASASIGLVANIAANLIAFLAILGFINATLRWLGGMVGYPDVTFELICSFVFMPVAFMMGIPYDESFKVAELIGTKLFLNEFIAYEKLSELKNNRLNGILDDNGDPN-WISVRSEIICTYALCGFANFSSLGIVIGGLSSICPPKKGVISSLVLRALFTGTCVSLINACIAGILFVPP---LDCVGLLQNAVFEPTTANLETCCYDLFKSTVNNGTVSFEGSWSVVANATIYFENCCGLYNATVCM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7N3-1", "uniprot_id": "A1Z7N3_DROME", "id": "A1Z7N3-1", "name": "", "aln": "MAEPIEGEQEEKPPPSRAKRITYLVLHVLLHIIFISYFTAATIIFIFYDKDSKECWPNRGSE--ATTESIDNSTEDDDDDDYDTEETSEKPVPEVKPKLLCQINWCHGYGFLIVLFILFYILWLYYWVFKPFVGIKLYNNYLEPVIDKWIAFSRQWIVSGVMLAIVLAVVVAYLGFECRNDAYKAIGLLGPVCFVLIGFAVSKHHLQVPWRIVTHGLLGQLLLGILCLRLPFGRSIFQCLGDKVTIFLNYAQHGARFVYGDRICDEYVFAFAILAVVFFFSVITSIMYYLGWMQFILNGFGFLLQAMVGTTVCESVNAAGNVFLSMTESPLVIRPYIEILTVSELHAICTSGYATVAGTVLGAYVSFGASASFLIAASVMAAPGSLAFAKLFYPETEESLTRSDN-IKLESSTDTSILDAAASGAAAALLIVLGIVSNIIAFLAIVFFLDAVTEWIFELIGLHNITLLYILSQIFIPIVFVMGVPWHDCQAIGLVVAQKSFINEFVAYRNLGILVSDKK-------------VDPRSAAIATFALCGFANPGSLGIVIASLSAMAPSRRSDITRVAFRSYFAGSFVSFTSASLAGILIQNEYTGGN----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :*. . : . : .: . : . . . :: .: :.:: . : * :. * .: . : *: : . :: :*..: : . : :.: * *: * * *: * * * ** *: :*:: :* * *: **.:: :**.*:: *: **:*: : .: :*** *.::.*** : *::*::* **::: :.:::*. :**: *::..***:*:. **:**:****: :* **:*.: *.*:**:**:::**::*** .*: **:******* :**::** ***.*:* .. :*: . .:::*.: **: :: :* .*.:*:*****:: *::*. *: ::. .::: * * :: *:.*:**:.:.:. :. ::. * *:***:**..*. . : :. *: : *:******* .*:**::..*::: * ::. :: :.:*: ::*: **: .*.:**** : ", "identical_positions": 144, "similar_positions": 203, "identity": "21.49%" }, { "cls_id": "homologset.agr.RGD:621224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIH3-1", "uniprot_id": "S28A3_RAT", "id": "Q8VIH3-1", "name": "Solute carrier family 28 member 3", "aln": "MSRSDPDPGKNSEPSKSKMSLELR-PTAPSDQGRLNEAFQDED--LEEQNAPGNSTVRSRVVQSGEQGRAKQDDRQITIEQEPLGPKEGTEEESEDERQKGFLERKYDTVCEFCRKHRVILQHTIWAVLLTGFLALVIAACALNFHRALPLFVITLVTIFFVVWDRLMAKYEQRIDDVLSPGKRLLERHWFWLKWVVWCSLILAVILWLALDTARLGQQQLISFGGLVMYIVLLFLFSKHPTRVYWRPVFWGIGLQFLLGLLILRTRPGFVAFDWMGKQVQTFLGYTDAGAQFVFGEKYT-DHFFAFKILPIVVFFSTVMSMLYYLGLMQWIIRKVGWLMLVTMGSSPIESVVAAGNIFVGQTESPLLVQPYLPHVTKSELHTIMTAGFATIAGSVLGAYISFGVSSTHLLTASVMSAPAALAVAKLFWPETEKPKITLKNAMKMENGDSRNLLEAATQGASSSIPLVANIAANLIAFLALLSFVNSALSWFGSMFDYPQLSFELICSYIFMPFSFMMGVDWQDRFMVAKLIGYKTFFNEFVAYEHLSKFINLRKAAGPKFVNGVQQYMSIRSETIATYALCGFANFGSLGIVIGGLTSIAPSRKRDIASGAMRALIAGTIACFMTACIAGMLSDTPVAINCHHVLE---SSKVLSNTTEVASCCQGLFNSTVARGPNDVLPGGNFSLYTLKSCCNLLKPPTLNCGWIPNIP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERH8-1", "uniprot_id": "S28A3_MOUSE", "id": "Q9ERH8-1", "name": "Solute carrier family 28 member 3", "aln": "MSRADP--GKNSEPSESKMSLELR-PTAPSDLGRSNEAFQDED--LERQNTPGNSTVRNRVVQSGEQGHAKQDDRQITIEQEPLGNKEDPEDDSEDEHQKGFLERKYDTICEFCRKHRVVLRSTIWAVLLTGFLALVIAACAINFHRALPLFVITLVTIFFVIWDHLMAKYEQRIDDFLSPGRRLLDRHWFWLKWVVWSSLILAIILWLSLDTAKLGQQNLVSFGGLIMYLILLFLFSKHPTRVYWRPVFWGIGLQFLLGLLILRTRPGFVAFDWMGRQVQTFLGYTDTGARFVFGEKYT-DHFFAFKILPIVVFFSTVMSMLYYLGLMQWIIRKVGWLMLVTMGSSPIESVVAAGNIFIGQTESPLLVQPYLPHVTKSELHTIMTAGFATIAGSVLGAYISFGVSSTHLLTASVMSAPAALAVAKLFWPETEKPKITLKSAMKMENGDSRNLLEAASQGASSSIPLVANIAANLIAFLALLSFVNSALSWFGSMFNYPELSFELICSYIFMPFSFMMGVDWQDSFMVAKLIGYKTFFNEFVAYDHLSKLINLRKAAGPKFVNGVQQYMSIRSETIATYALCGFANFGSLGIVIGGLTSIAPSRKRDIASGAMRALIAGTIACFMTACIAGILSDTPVDINCHHVLE---NGRVLSNTTEVVSCCQNLFNSTVAKGPNDVVPGGNFSLYALKSCCNLLKPPTLNCNWIPNKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAS3-1", "uniprot_id": "S28A3_HUMAN", "id": "Q9HAS3-1", "name": "Solute carrier family 28 member 3", "aln": "--------------------MELRSTAAPRAEGYSNVGFQNEENFLENENTSGNNSIRSRAVQSREHTNTKQDEEQVTVEQDSPRNREHMEDDDEEMQQKGCLERRYDTVCGFCRKHKTTLRHIIWGILLAGYLVMVISACVLNFHRALPLFVITVAAIFFVVWDHLMAKYEHRIDEMLSPGRRLLNSHWFWLKWVIWSSLVLAVIFWLAFDTAKLGQQQLVSFGGLIMYIVLLFLFSKYPTRVYWRPVLWGIGLQFLLGLLILRTDPGFIAFDWLGRQVQTFLEYTDAGASFVFGEKYK-DHFFAFKVLPIVVFFSTVMSMLYYLGLMQWIIRKVGWIMLVTTGSSPIESVVASGNIFVGQTESPLLVRPYLPYITKSELHAIMTAGFSTIAGSVLGAYISFGVPSSHLLTASVMSAPASLAAAKLFWPETEKPKITLKNAMKMESGDSGNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWFGNMFDYPQLSFELICSYIFMPFSFMMGVEWQDSFMVARLIGYKTFFNEFVAYEHLSKWIHLRKEGGPKFVNGVQQYISIRSEIIATYALCGFANIGSLGIVIGGLTSMAPSRKRDIASGAVRALIAGTVACFMTACIAGILSSTPVDINCHHVLENAFNSTFPGNTTKVIACCQSLLSSTVAKGPGEVIPGGNHSLYSLKGCCTLLNPSTFNCNGISNTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7N3-1", "uniprot_id": "A1Z7N3_DROME", "id": "A1Z7N3-1", "name": "", "aln": "----------------MAEPIEGEQEEKPPPSRAKRITYLVLHVLLHIIFISYFTAATIIFIFYDKDSKECWPNRGSEATTESIDNSTEDDDDDDYDTEETSEKPVPEVKPKLLCQINWCHGYGFLIVLFILFYILWLYYWVFKPFVGIKLYNN---------------YLEPVIDKWIAFSR-------QWIVSGVMLAIVLAVVVAYLGFECRNDAYKAIGLLGPVCFVLIGFAVSKHHLQVPWRIVTHGLLGQLLLGILCLRLPFGRSIFQCLGDKVTIFLNYAQHGARFVYGDRICDEYVFAFAILAVVFFFSVITSIMYYLGWMQFILNGFGFLLQAMVGTTVCESVNAAGNVFLSMTESPLVIRPYIEILTVSELHAICTSGYATVAGTVLGAYVSFGASASFLIAASVMAAPGSLAFAKLFYPETEES-LTRSDNIKLESSTDTSILDAAASGAAAALLIVLGIVSNIIAFLAIVFFLDAVTEWIFELIGLHNITLLYILSQIFIPIVFVMGVPWHDCQAIGLVVAQKSFINEFVAYRNLGILVSDKK-------------VDPRSAAIATFALCGFANPGSLGIVIASLSAMAPSRRSDITRVAFRSYFAGSFVSFTSASLAGILIQN-------------------------------------------EYTGGN---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . * . : . *. . .: : :. . :. :. :::.: :: : :. : : . : :*: : : : .:: . .: *: * **. :: .: *: : :::**::. .: . : :.: * : :::: * .**: :* ** * *: *:***:* ** * *: :* :* ** *:: ** **:*:: ::.*** :*.:*.***.: *::**** **:*:. .*::: . *:: *** *:**:*:. *****:::**: :* ****:* *:*::*:**:*****:***..::.*::****:**.:** ****:****:. :* .. :*:*.. . .:*:**:.**:::: :* .*. *:*****:: *:::. .*: .::. :::: * * **:*: *:*** *:* :. ::. *:*:****** :*. : :* :. ** ***:******* *******..*:::****: **: *.*: :**:...* :*.:**:* .. .*** ", "identical_positions": 184, "similar_positions": 208, "identity": "25.84%" }, { "cls_id": "homologset.agr.RGD:621225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJ92-1", "uniprot_id": "PP4C_RAT", "id": "Q5BJ92-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "----MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMTCRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRG----IPSKKPVADYFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60510-1", "uniprot_id": "PP4C_HUMAN", "id": "P60510-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "----MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRG----IPSKKPVADYFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97470-1", "uniprot_id": "PP4C_MOUSE", "id": "P97470-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "----MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRG----IPSKKPVADYFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A9JRC7-1", "uniprot_id": "PP4CB_DANRE", "id": "A9JRC7-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit B", "aln": "----MGDMSDLDRQIDQLRRCELIKENEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKEFIIFEAAPQETRG----IPSKKPVADYFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8WGP3-1", "uniprot_id": "PP4CA_DANRE", "id": "A8WGP3-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit A", "aln": "MCVIMGDFTDLDRQIEQLRRCELIKENEVKALCAKAREILVEESNVQSVDSPVTVCGDIHGQFYDLKELFRVGGEVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFFDECHRKYGSATVWRYCTEIFDYLSLSAIVDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDISMICRAHQLVMEGYKWHFNDTVLTVWSAPNYCYRCGNVAAILELDEHLQKEFIIFEAAPQETRG----LPSKKPVADYFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76932-1", "uniprot_id": "PP4C_DROME", "id": "O76932-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "----MSDYSDLDRQIEQLKRCEIIKENEVKALCAKAREILVEEGNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPEKNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSTAVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQYLDQIRSIDRKQEVPHDGPMCDLLWSDPEDQTGWGVSPRGAGYLFGSDVVSQFNRTNDIDMICRAHQLVMEGFKWHFNETVLTVWSAPNYCYRCGNVAAILELNEYLHRDFVIFEAAPQESRG----IPSKKPQADYFL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32345-1", "uniprot_id": "PP4C_YEAST", "id": "P32345-1", "name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "aln": "-------MMDLDKIIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDTWSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFEAVQAQNEVGNAIIPTKKSQMDYFL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***: * .*: : * *. * ** :::*:*::*.** **:***:*******::** **. .* * :..*:*:*******:**:*:*****. *:**************:****:****:** ****. ***** *:******.**::..**********.: :*:**:*********:*.*********** *.:******:***. * ** *::.: .*********:* *: ::*****************:*:::: *:::: ****. :.. :*:**. ****", "identical_positions": 182, "similar_positions": 74, "identity": "57.78%" }, { "cls_id": "homologset.agr.RGD:621226", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERE4-1", "uniprot_id": "GOLP3_RAT", "id": "Q9ERE4-1", "name": "Golgi phosphoprotein 3", "aln": "MTSL----TQRSSGLVQRRTEASRNAADKERAAGGGGGNGEDEAQSRR---DEQDDDDKGDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRKSLLTRKVICKSDAP-TGDVLLDEALKHVKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQEAVLDK---------WVNDPHRMDKRLLALIYLAHASDVLENAFAPLLDEQYDLATKRVRQLL--------DLDPEVEC-LKANTN-----------------EVLWAVVAAFTK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CRA5-1", "uniprot_id": "GOLP3_MOUSE", "id": "Q9CRA5-1", "name": "Golgi phosphoprotein 3", "aln": "MTSL----TQRSSGLVQRRTEASRNAADKERAAGGGGGSGEDEAQSRR---DEQDDDDKGDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRKSLLTRKVICKSDAP-TGDVLLDEALKHVKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQEAVLDK---------WVNDPHRMDKRLLALIYLAHASDVLENAFAPLLDEQYDLATKRVRQLL--------DLDPEVEC-LKANTN-----------------EVLWAVVAAFTK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4A6-1", "uniprot_id": "GOLP3_HUMAN", "id": "Q9H4A6-1", "name": "Golgi phosphoprotein 3", "aln": "MTSL----TQRSSGLVQRRTEASRNAADKERAAGGGAGSSEDDAQSRR---DEQDDDDKGDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRKSLLTRKVICKSDAP-TGDVLLDEALKHVKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQEAVLDK---------WVNDPHRMDRRLLALIYLAHASDVLENAFAPLLDEQYDLATKRVRQLL--------DLDPEVEC-LKANTN-----------------EVLWAVVAAFTK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VQ93-1", "uniprot_id": "GOLP3_DROME", "id": "Q9VQ93-1", "name": "Golgi phosphoprotein 3 homolog sauron", "aln": "--------MNRSDGLVRRSVKPRENGGAEGGLNANTPDDNQDALDNLK---DQEDNIDDGDSKETRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGCILIELGLRGRVMIEKSGMRRRGLCTRKLILKSDQQ-TGDVLLDEALKHIKETDPPETVQSWIEYLSGETWNPLKLRYQLKNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLSDNVVKCRLVKKIQDSVLSK---------WVNDPQRMDKRMLALIFLAHASDVIENAFAPLNDDDYEVAMKRVRELL--------DLDFEAES-AKPNAN-----------------EILWAVFMAFTK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06385-1", "uniprot_id": "VPS74_YEAST", "id": "Q06385-1", "name": "Vacuolar protein sorting-associated protein 74", "aln": "MSTLQRRRVNRADSGDTSSIHSSANNTKGDKIANIAVDGDDDNGTNKKIAYDPEESKLRDNINIPTLTLMEEVLLMGLRDREGYLSFWNDSISYALRGCIIIELALRGKIRILDDSARKRFDLSERLIEVIDSSKTGEVLLDETLQLMKNDEP-LSISNWIDLLSGETWNLLKINYQLKQVRERLAKGLVDKGVLRTEMKNFFLFDMATHPIADASCKEAIKRRVLSVLVSRNMELSYNEYFPETTSFKIIRTLALICGSYGANVLENVLTTLEYEKRDKAISRAEEIMAQFSQYPFDLEKETELGVSVNLNKEVKEEIENNPGHDLQLEVIAGVFEVFSRMDMLL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:.. .. * ...:* . : * ::. .: : . *********:**:*:*** *****.** .****::***.***:: : . *:: :.::* * **:*****:*: :*: :* ::..**: ******* **:.***::*******.**:**** ** :**:****:***::: * : ::: . ::.: : : . * **** ::.::*:**.::.* :. : * .*..::: **: *.* . * * *:: .*. .*:: ", "identical_positions": 108, "similar_positions": 101, "identity": "31.21%" }, { "cls_id": "homologset.agr.RGD:621227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIB2-1", "uniprot_id": "DAXX_RAT", "id": "Q8VIB2-1", "name": "Death domain-associated protein 6", "aln": "----------------------------------------------------------------------------------------------MATDDSIIVLDDDDEDEAAAQPGPSNPASNPVSPGP------EASGPSESHGDGGSSN---------------------------------------SGSRKCYKLENEKLFEEFLELCKMQTSDHPEVVPFLHKLQQRAQSAFLASAEFRNILSRVLSRSRNRPAKLYVYINELCTVLKAHSIKKK---LNLAPAAS--AESSGDNPPTDPPSDLTNTETTASEASR----TRGSRRQIQRLEQLLALYVAEIQRLQEKELDLS--------------------------------------------ELDDPDSSYLQEARLKRKLIRLFGRLCDLKDCSSLTGKVIEQRIPYRGTRYPEVNRRIER-------------LINKP-GPDTFPDYG--DVLRAVEKAATRHSLGLPRQQLQLLAQDAFRDVGVRLQERRHLDLIY-NFGCHLTDDYRPGVDPALTDPTLARRLRENRTLAMSRLDEVISKYAMMQDKSEEGE------RQKRRARLLATS-QSSDLPKASSDSGEGPSGVASQEDPTTPKAETEDEEDDEESDDE-------EEEEEEEEEEATE-DEDEDLEQLQEDQD-DEEEEEGD-------------------------NEDDKSPASPSPIFRRKEFSNPQKGSGP-QEEQQERGLTGTPASPLEASPGLPSTDAESSGEQLQERLLAGESPVSQLSELDMEALPEETI--PSPEERGISSSRRKSDSSLPTILENGAAMVTSTSFNGRVSSHPCRDASPPSKRFRKEKKQLGPGPLGNSYVKKQTMAQQDSGWKISVLSTPSSPLAS-----VGPVADSSTRVD--------SPSHELVTSSLCNPSPSLILQTPQSQSPRPCIYKTSVATQCDPEEIIVLSDSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35613-1", "uniprot_id": "DAXX_MOUSE", "id": "O35613-1", "name": "Death domain-associated protein 6", "aln": "----------------------------------------------------------------------------------------------MATDDSIIVLDDDDEDEAAAQPGPSNLPPNPASTGPGPGLSQQATGLSEPRVDGGSSN---------------------------------------SGSRKCYKLDNEKLFEEFLELCKTETSDHPEVVPFLHKLQQRAQSVFLASAEFCNILSRVLARSRKRPAKIYVYINELCTVLKAHSIKKK---LNLAPAASTTSEASGPNPPTEPPSDLTNTENTASEASR----TRGSRRQIQRLEQLLALYVAEIRRLQEKELDLS--------------------------------------------ELDDPDSSYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIER-------------LINKP-GLDTFPDYG--DVLRAVEKAATRHSLGLPRQQLQLLAQDAFRDVGVRLQERRHLDLIY-NFGCHLTDDYRPGVDPALSDPTLARRLRENRTLAMNRLDEVISKYAMMQDKTEEGE------RQKRRARLLGTAPQPSDPPQASSESGEGPSGMASQECPTTSKAETDDDDDDDDDDDEDNEESEEEEEEEEEEKEATE-DEDEDLEQLQEDQGGDEEEEGGD-------------------------NEGNESPTSPSDFFHRR-NSEPAEGLRT-PEGQQKRGLTETPASPPGASLDPPSTDAESSGEQLLEPLLGDESPVSQLAELEMEALPEE---------RDISSPRKKSEDSLPTILENGAAVVTSTSVNGRVSSHTWRDASPPSKRFRKEKKQLGSGLLGNSYIKEP-MAQQDSGQNTSVQPMPSPPLAS-----VASVADSSTRVD--------SPSHELVTSSLCSPSPSLLLQTPQAQSLRQCIYKTSVATQCDPEEIIVLSDSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UER7-1", "uniprot_id": "DAXX_HUMAN", "id": "Q9UER7-1", "name": "Death domain-associated protein 6", "aln": "----------------------------------------------------------------------------------------------MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGA------EAPSSSEPHGARGSSS---------------------------------------SGGKKCYKLENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRPAKLYVYINELCTVLKAHSAKKK---LNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPR----TRGSRRQIQRLEQLLALYVAEIRRLQEKELDLS--------------------------------------------ELDDPDSAYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIER-------------LINKP-GPDTFPDYG--DVLRAVEKAAARHSLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIY-NFGCHLTDDYRPGVDPALSDPVLARRLRENRSLAMSRLDEVISKYAMLQDKSEEGE------RKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEE-------EEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAG--------------------KDGDKSPMSSLQISNEKNLEPGKQISRS-SGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDT---PSSVETDISSSRKQSEEPFTTVLENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKICTLPSPPSPLAS-----LAPVADSSTRVD--------SPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTCKTSVATQCDPEEIIVLSDSD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HYH8-1", "uniprot_id": "A0AC58HYH8_DANRE", "id": "A0AC58HYH8-1", "name": "Death domain-associated protein 6", "aln": "-------------------------------MLLTNKRKESVWHVRIKELQSSNQKVNADFET-----PVWILTVLINSMLSAQQIRSPPFRMAGAGMESIVILDDDDEEAASTSASCSQATAQHLKTPVK---SQPVPAPTHITQSPFASA---------------------------------------KKDTHVLKVENEKLFNEFVEHCSKHSQEHPEVMTYLQTRYSKALPTFLTSVEFRNTLGRCLTRAQANAGKTFVYINELCTVLKQHTPRKRSSIQSLSVKAKPEEKSNGVNVKEDTQGEQDGGKDVKQQEEESKKTKRASRRQIAYLENLLKVYNEEIRRLQEGDLSLD--------------------------------------------DLEKEDSSYIQEHKLKRKMMKIYEKLCELKGCNTLTGRVIEQKIPYSGTRYPEINKKVER-------------FINSSEALLNPPDYS--DILKIVQRANERYNLQLSRKQQAQISQEAFRETGNKLQERRHLDMVY-NFGSHLTDPYKPTLDPALMDPALHRKLRSNRDVAISSLEEVINKYANKQEDMEVEE------TKKRQDRERLKKEAVNGQQSESKEK------------------EKEEQEEKEKEDEE-------EEEEDEEEDDSSDPDIEDEIQASEQQAGPEDDEEDVE-----------------------------EEPANISDNDQPINESSPLSIKSS-VQDTEEDEEQSPLSSTHEGSAETNTNTNGPAKQSLESTEIKPES-------IKPESIKPES------IKPETIKPESIKPENTDSLAEVKTEQVSSNHVEAVSASTETVSIVSEESSTAVTRSANCSPLLPTSPLLIDETGNYRKRKRRSTENHTSAHNGN-----CTEDSDIPLDMG--------VICCSEQEDLTCLKTPPRKTARNSQATPPPKKNKVNVATQCDPEEVIVLSDSE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMD0-1", "uniprot_id": "DAXX_DROME", "id": "Q9VMD0-1", "name": "Daxx-like protein", "aln": "MSASVICVDLSSESDEESPAKRRRLEDPLRLLTPSGRQSFPAKLLNIPKASLGSAMVVPVAETGPARETPVIVDPLRSMHIPSGITITKHQKNVLATNGNMNLSLAESNNNNNTTSLNKNVTPKQINVGTGQKVAWSVSSKAPSPNAVITTVPSHQVRVTPFNPIRLAPGSKIIPASNAMPAKIQPILGMGQPQQQAQAQQPKAIIVGFPKPNTAVAQMAQHQKPLTLQIHQKLIAGQQQHIASISQLQQVSLQQQQPLRPVSIQLQQQQNQRNGSLPGKQQKPLECPVPAQQEKLPRGP-LPTKPAEPLSGPLPTEPDEPLGGPLPTRPKPPVRSLQQPVNKNTAIGVQIQQSQEPLGGTLPTRQKPLGGQLLTQQKPPVGSIQQSVKQNTGIGVQIQQIPKVVVGQQPQKVYLNKLQQEQQKIFLGHLQQQQQKTFLGQLQQEQQKILGQLQQQKQQQQQQQKKILGQSQQQKVPLGQPQPQQKLPQQLNNSLVQLQQQHQQRTSVGQLQQQQPHQSQQKNSMVHVKQQPQQQKKISVGQFQQQPQQQQKTSVAQLQQQPQQQQKISVGQLQQQSQQQQKPSVGQLQQQSQQQQTPLVGQLQRQTQQQQKTSAGQFQQQPQQQQKISAGQLQEHSQQQQKTLAGQLQQQAQQQLNTSAGQLQQQQKPPKASLAQQAAAQKQGAGLGQQQQFQSQPQQRTSAGLLQQQQMPQKKIVMQPQLPKTSVVLPRPQQLPKNPLLVAQQQSPKTPLVNSVMGPQFPSQQPSLPVVNQITHKSMTIQRLPMLQTVQKILPKQIAPQQTPPPAHIVQKQTMPNAAMQNPPFAHRPPIVRPMTVAKISPVPTNNKVCIPMKPQMASYVSPTDPTMTAARTLPFRSSQRKTSEAPMTSTHVQGFTASATPPQRLLATPPHCAAALNEPLLLNLPPTTSITPQLTPTTTPPPAGPSAAVQQQQLAKAAAIKLNSLPEASISPVNRSPTASAKRIQPITVLKKSDEEWQRHLEQQQQKKHVQLQSSSMTTIVLVESPPTTPPTDKPEPERGPMTVEKSSIKPMATDKQSRAIKRPAVMISTKKSGLVVTEIVDLDEIPDIPPEKRGKECFPPIKNAAKAAPSVNAPFTTEYAALLRLCREVDKSTHMERLVKGELTQYYYSAPESFVMSCGFRNLVTMAMARIRSESYLVYVHLKYVLDELASRRLTKMFPTVRAIPPASQFPLPPASQFPLPPTLTTPKQPAIVKAPGQQTVMAGREQDDEVEEVTLVNVGTVSCEERRRDERIRHFYRTLHAITKRIKMLEEAEVDLNDEDSSYLQLERFKKRACQIYEKICDLKGESKSVRRQLKKPIHFKDSDYPHFNNSLSAFVNRMQDFPDYHDVLQILEKCNKEKELGLAKYEMKRIAYDAFNKVGRMLQSRRKNDLYETVTHYTANGKDPASSDPELLAKLKENNKKQTKISDILEKYALEQDLNAEERQEARLKEKKLKQVKADEEAAKLAALAEDDDKPCTSAQAAAKAAALAALKRGPAARGNVIRKKRAANGRIFKIADDGDDSEEESDSEDDDVEEFVNNFQANSDVSDADSEVEAVTSPKRDALPLAEEEDVIDITRDETGKKNDEGTPNGRLKIMSVSSLNANFVHGQDLHRKPNPMPSAKPVIADQIIISDEES", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: : :.:: : . .: .: . ... : :: . : : : :: * : . : . . .: . . * : : : : ::: . : *: . . * . * . . . : .: : *:: : ::*: : *. : :. : :*::: ::: : : .:: *:: ::: * : ::: :: :... . *: .::: :: * .: ::* :*: . : * ::: .: :* : : :. : :* ::: .: . :: . *:. : :: : : . . . . : ::: :.: . . : : . .::: . : :: ::. : * . . . .: . :. : :. :. ::: . : . . . . :. . : : .: : .. .. . :. . : . . . :. . *.: :* :: **.: ", "identical_positions": 25, "similar_positions": 218, "identity": "1.51%" }, { "cls_id": "homologset.agr.RGD:621228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VFX0-1", "uniprot_id": "Q9VFX0_DROME", "id": "Q9VFX0-1", "name": "Aminopeptidase", "aln": "-------------------MIVTAKLVAIGLGLALTAFTVSTIVLAVQKANLKSDLRDAQEKLDLLEAGYTSTAAPTTASTANPGSTASPGSTAEPGSTAEPGSTAEPGSTASPGSTVTP--GSTASTSEPGTTASPEKIDYRLPGTLKPTHYDLYLF-PNIETGEFSGQETITITVEEATDQIVLHSLNLNISSVSIMNTGSDTLEILETT-----VDAVREFLIFQLNEPLTKGR---TVRLHIGFEGSMA------NKIVGLYSSSYVKEDETR--KWIATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSNMNVD-SSVSQG-AFQEVTFAKSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQLDKVDLAVTIGKGVIEYYIDYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYDE-ATSSATNKQRIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLGVD--AVYPEWKMRDQFTVSTLHSVLTLDGTLGSHPIIQTVENP-----DQITEIFDTITYSKGSSLVRMLEDFLGETTFRQAVTNYLNE---YKYSTAETGNFFTEIDKLE-LGYNVTEIMLTWTVQMGLPVVTIEKVSDTEYKLTQKRFLSNPNDYDADHEPSEFNYRWSIPITYFTSSDSVVQRLWFYHDQSEITVT--VPAAVEWIKFNADQVGYYRVNYDTDLWNDLADQLVVQPSAFGSVDRAHLLNDAFALAD---STQLPYATAFELTRYLDKETDYVP---WSVAASRLTSLKRTLYYT-STYAKYKKYATALIEPIYTALTWTVGED-HLDNRLRVTALSAACSLG--LESCLTEAGEQFNAWLAKPEDRPKADVRETVYYYGIQSVGSQEDWDAVWELFVNESDASEKSKLMYGLSAIQIPWILQRYIDLAWN-EEYVRGQDYFTCLTYISANPVGESLVWDYVRENWQRLVDRFGLNERYLGNLIPSITARFSTQTKLEEMEQFFAKYPEAGAGTAARV-----------------RALETVKNNIVWLAENLEGVDAWLD--KQPL--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VFW9-1", "uniprot_id": "Q9VFW9_DROME", "id": "Q9VFW9-1", "name": "Aminopeptidase", "aln": "-------------------MFLSGYWLQVVLSWAVVAFATATVVVAVQKAQLERDLRDVQDKIDVFEEWS--------------------------------------------GESRTR--MKREDTT-----------DYRLPTNLVPTHYELYWH-PDLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYVLNREVEKFELEEE----------RQFLIITLTEELAVDA---SITLGIIFGGQMK------DKLVGLYSSTYLNEAGAT--RTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSG-SYHAVSNMQQT-ESNYLG-DYTEAIFETSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSMQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDP-SYSSTANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVN--AVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESP-----DEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVK---HQFNNTVTDDFLTEVEAVV-TDLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFAD-DGSENSFIYDYDVDSVGIA--VPSEVQWIKLNVNQTGYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAFALAD---ANQLSYKIPLDMTAYLAQERDFVP---WYVASNKLRSLHRSLMFS-EGYVSYLTYARSLIAGVYEEVGWTVDADNHLKNRLRVSILTAACALG--VPDCLQQASERFSTFLENPTTRPSPDLREIVYYYGMQQSTSQSSWDQLFQLFVAETDASEKLKLMYGLSGVRNSQYLFDFLAQASSDESIVRSQDYFTCVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHFFSKYPESGAGANSRL-----------------EAVETIKYNIEWLSRNEADITDWLSGTASPLTKKNQL--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INH6-1", "uniprot_id": "Q8INH6_DROME", "id": "Q8INH6-1", "name": "glutamyl aminopeptidase", "aln": "MYAAKNVRPRSSLSTDDNHRIKDTNRPHKARSNTILTLAAFCVFLLVLCGFLLGALVYVGKNIAEEHQRQQHANASQWALNSTIRTVYVDRDQLLSTKPIISVLSDNRFYTTQVPTSKKSSIMATVAPAVKAASKVLQNLGFRLPKQIKPSKYRLHLR-PDLERKNYSGNISISLQVLEPIAFIPVHVKQLNVSTVEVKRLDESGAPLKDITPTLTFAHPEFEYWVTEFEQPLEAG----NYSLLLNFTGSLV------DRITGMYQSSYLDKLKNRS-RSIISTKFEPTYARQAFPCFDEPALKAQFTITVARPSGDEYHVLSNMPVA-SEYVDG-DITEVTFAETVPMSTYLAAFVVSDFQYKETTVEG----TSIALKVYAPPAQVEKTQYALDTAAGVMAYYINYFNVSYALPKLDLVAIPDFVSGAMENWGLVTFRETALLYDE-STSSSVNKQRVAIVVAHELAHQWFGNLVTMNWWNDLWLNEGFASFLEYKGVK--QMHPEWDMDNQFVIEELHPVLTIDATLASHPIVKSIESP-----AEITEYFDTITYSKGAALVRMLENLVGEEKLRNATTRYLVR---HIYSTATTEDYLTAVEEEEGLEFDVKQIMQTWTEQMGLPVVEVEKSGS-TYKLTQKRFLANEDDYAAEAEASSFNYRWSIPITYTSSINSEVQSLIFNHNDNEATIT--LPEEASWIKINTNQVGYYRVNYGSEQWAELISALKNSRETFSTADRAHLLNDANTLAA---AGQLNYSVALDLISYLESEQDYVP---WSVGTSALATLRNRVYYT-DLYTNYTTYARKLLTPIVEKVTFTVAAD-HLENRLRIKVLSSACSLG--HESSLQQAVTLFNQWLASPETRPNPDIRDVVYYYGLQQVNTEAAWDQVWKLYLDESDAQEKLKLMNCLTAVQVPWLLQRYINWAWD-ESNVRRQDYFTLLGYISTNPVGQSLVWDYVRENWEKLVDRFGINERTLGRLIPTITARFSTETKLEEMQQFFAKYPEAGAGTAARQ-----------------QALEAVKANIKWLAANKAQVGEWLANYVQQSSVTNRIQ-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P16406-1", "uniprot_id": "AMPE_MOUSE", "id": "P16406-1", "name": "Glutamyl aminopeptidase", "aln": "-----------------MNFAEEEPSKKYCIKGKHVAIICGVVVAVGLIVGLSVGLTRSCEQ------DTTPAPS----------------------------------QPPPEAS--TALPPQDQNVCPDSEDESGEWKNFRLPDFINPVHYDLEVK-ALMEEDRYTGIVTISVNLSKPTRDLWLHIRETKITKLPELRRPSGEQVPIRRC----FEYKKQEYVVIQAAEDLAATSGDSVYRLTMEFKGWLN------GSLVGFYKTTYMEDGQIR---SIAATDHEPTDARKSFPCFDEPNKKSTYSISIIHPKE--YSALSNMPEEKSEMVDD-NWKKTTFVKSVPMSTYLVCFAVHRFTAIERKSRS-----GKPLKVYVQPNQKETAEYAANITQAVFDYFEDYFAMEYALPKLDKIAIPDFGTGAMENWGLVTYRETNLLYDP-LLSASSNQQRVASVVAHELVHQWFGNTVTMDWWDDLWLNEGFASFFEFLGVN--HAEKDWQMLSQVLLEDVFPVQEDDSLMSSHPVVVTVSTP-----AEITSVFDGISYSKGASILRMLQDWITPEKFQKGCQIYLKK---FQFANAKTSDFWDSLQEAS--NLPVKEVMDTWTSQMGYPVVTVSGRQN----ITQKRFLLDSKADPSQP-PSELGYTWNIPVRWADN-DNSRITVYNRLDKGGITLN-ANLSGDAFLKINPDHIGFYRVNYEGGTWDWIAEALSSNHTRFSAADRSSFIDDAFALAR---AQLLNYKIALNLTMYLKSEEDFLP---WERVISSVSYIISMFEDDRELYPMIETYFQGQVKPVADLLGWQDTGS-HITKLLRASILGFACKMG--DREALGNASQLFDSWLKGSASIP-VNLRLLVYRYGMQNSGNEAAWNYTLEQYQKTSLAQEKEKLLYGLASVKDVKLLARYLEMLKD-PNIIKTQDVFTVIRYISYNSYGKTMAWNWIQLNWDYLVSRFTINDRYLG-RIVTIAEPFNTELQLWQMQSFFAKYPNAGAGAKPRE-----------------QVLETVKNNIEWLNVNRQSIREWFASLP-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50123-1", "uniprot_id": "AMPE_RAT", "id": "P50123-1", "name": "Glutamyl aminopeptidase", "aln": "-----------------MNFAEEEPSKKYCIKGKHVAIICATVVAVGLIVGLSVGLTRSCEP------GTTPAPS----------------------------------NPPPHTS--TALPPQDQNVCPDSDDESGEWKNFRLPDFIQPVHYDLEVK-VLMEEDRYTGIVSISVNLSKDTRDLWLHIRETRITKLPELRRPSGEQVPIRRC----FEYKKQEYVVIQAEEDLAATSGDSVYRLTIEFEGWLN------GSLVGFYRTTYTEDGQTK---SIAATDHEPTDARKSFPCFDEPNKKATYNISLIHPKE--YSALSNMPVEKKETLDN-DWKKTTFMKSVPMSTYLVCFAVHQFTSIQRTSRS-----GKPLTVYVQPNQKQTAEYAANITKAVFDFFEDYFAMEYSLPKLDKIAIPDFGTGAMENWGLVTYRETNLLYDP-LLSASSNQQRVASVVAHELVHQWFGNIVTMDWWDDLWLNEGFASFFEFLGVN--HAEADWQMLSQVLLEDVLPVQEDDSLMSSHPVVVTVSTP-----AEITSVFDGISYSKGASILRMLQDWITPEKFQKGCQIYLEN---FKFKNAKTSDFWDSLEKAS--NQPVKEVMDTWTSQMGYPVVTVSGKQN----VTQKRFLLDYKADPSQP-PSALGYTWNIPIKWTEN-GNSNITVYYRSNREGITLN-ANLSGDGFLKINPDHIGFYRVNYEAETWDWIAETLSSNHMNFSSADRSSFIDDAFALAR---AQLLDYEKALNLTRYLTSEKDFLP---WERVISAVSYIISMFEDDRELYPLIETYFRSQVKPIADSLGWQDTGS-HITKLLRASVLGFACKMG--AGEALGNASQLFEAWLKGNESIP-VNLRLLVYRYGMQNSGNEAAWNYTLEQYQKTSLAQEKEKLLYGLASVKDVTLLARYLEMLKD-PNIIKTQDVFTVIRYISYNSYGKSMAWNWIQLNWDYLVNRFTINDRYLG-RIVTIAEPFNTELQLWQMQSFFAKYPNAGAGAKPRE-----------------QVLETVKNNIEWLKLNRKSISEWFTSMP-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q07075-1", "uniprot_id": "AMPE_HUMAN", "id": "Q07075-1", "name": "Glutamyl aminopeptidase", "aln": "-----------------MNFAEREGSKRYCIQTKHVAILCAVVVGVGLIVGLAVGLTRSCDSSGDGGPGTAPAPS----------------------------------HLPSSTASPSGPPAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVK-PLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRC----FEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLN------GSLVGFYRTTYTENGQVK---SIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKE--YGALSNMPVAKEESVDD-KWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNS-----GKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDP-KESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVN--HAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTP-----DEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEK---YQFKNAKTSDFWAALEEAS--RLPVKEVMDTWTRQMGYPVLNVNGVKN----ITQKRFLLDPRANPSQP-PSDLGYTWNIPVKWTED-NITSSVLFNRSEKEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALAR---AQLLDYKVALNLTKYLKREENFLP---WQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGD-HVTKLLRSSVLGFACKMG--DREALNNASSLFEQWLNGTVSLP-VNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKD-TNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLG-RIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPRE-----------------QVLETVKNNIEWLKQHRNTIREWFFNLLESG--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40462-1", "uniprot_id": "TM108_YEAST", "id": "P40462-1", "name": "Protein TMA108", "aln": "------------------------------MSDNLLSLENPVVPS-----------------------------------------------------------------------------------------------HYELRLEIDPKQSSPNFKGSAIIHLKFNPNSTTLASIEDSFTQFKLHSKDLIVLSAHATIGSTKFDLKISQD-------TGKHLSIFNSESPIQLSN-DCPLILSVQYVGKIRDIKTHHDKTFGIFKTNFMDRKTGTANNHVVATHCQPFSASNIFPCIDEPSNKSTFQLNIATDAQ--YKAVSNTPVEMVEALDSSQKHLVKFAKTPLMTTSVFGFSIGDLEFLKTEIKLEG-DRTIPVSIYAP-WDIANAAFTLDTVQKYLPLLESYFKCPYPLPKLDFVLLPYLSDMAMENFGMITIQLNHLLIPPNALANETVREQAQQLIVHELVHQWMGNYISFDSWESLWFNESFATWLACHILEQNGDLSHYWTSEPYLLQQVEPTMCRDAADVNGRSIFQIAQRNTGIDSQTSDIFDPEAYTKGIIMLRSLQLATGESHLQKGLESVFEDTKTFHARSVKPMDIWNHIGKFLK-SQNITNFVSSWTRTPGLPVVKVEVEEKDGKTQTKLTQHRFINQLSTEEKDQLEDVPYQVPLFGVLPDGKMDTKNVLLTDRT-------LKFDYPILVINHLAQGYYRVSYESEECYALINDKITEETLSEIDLRKIFLDLSQFIGDEGFQNSIHLHGLFKILNHIASPSTKIASKYWDPLSKGLEVLQTIDRASLTSSKLQSFLKKKIVIPLFNKIDWPHGEFDKSTNPHELKVMSQVLFLNKNSAKCAELCQIYFKHLLQGPRSSVPLELVNSILVVVSQHCANIKQWKKIFDLVKRSSCTGITNHVINMYDQNSSETAMLIQNGAIESLGFCLDSDIVKKTLNFITSNIESEGMELALFGFNYN-FKKRLNKNEKPQDQVVRETIWEWYMGNFDQWARKATRKGTTTGDHLHKALRSISLIIFQMFVADEPQKIEKFINLEKEKLGQSLLSLDDIWASVQQDEESRKTIRRDLASLV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :.* : * : : :. : : :* : . : . : * : : * : . *:: :.: . : ::. :* * : ***:*** *: : :.: * .:** . . . * : *:* : : : : . .: *. : .. : .*: *.*.*** :* : ***::*::* : . ** : :: :.**:.* *:** :::. *:.**:**.** :. :. .: . : : .. *. . : : : : ** :* ** ::* *: :.:. : . .. . : : :.:.: :** * **: :. . *: . . :.:*: . : : :* *:***.* : . * ::: : :. : :.: :: :. * . : : : : : : : : . . : . :. .. . *. * :: : * . *. . : : . ::: : . : : . : :*: * .: : :: : * *:: . : : . * . :* . : :: : * : ", "identical_positions": 83, "similar_positions": 217, "identity": "7.6%" }, { "cls_id": "homologset.agr.RGD:621229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24524-1", "uniprot_id": "GLRA3_RAT", "id": "P24524-1", "name": "Glycine receptor subunit alpha-3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHVRHFRTLLSGFYFWEAALLLSLVATKETNSAR-------------SRSAPMSPSDFLDKLMGRTSGYDARIRP------------------------NFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE---YPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYN--------TGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-------------------------------------------------------------------------------------------------------------------------------------------HKELLRFRRKRKNKTEAF---------------------------ALEKFYRFSDTDDEVRESRLSFT-AYGMGPCLQAKDG----------------VVPKGPNHAVQVMPKSAD--------------------EMRKVFID----RAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHHQQD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XP5-1", "uniprot_id": "GLRA3_MOUSE", "id": "Q91XP5-1", "name": "Glycine receptor subunit alpha-3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHVRHFRTLVSGFYFWEAALLLSLVATKETNSAR-------------SRSAPMSPSDFLDKLMGRTSGYDARIRP------------------------NFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE---YPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYN--------TGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-------------------------------------------------------------------------------------------------------------------------------------------HKELLRFRRKRKNKTEAF---------------------------ALEKFYRFSDTDDEVRESRFSFT-AYGMGPCLQAKDG----------------VVPKGPNHAVQVMPKSPD--------------------EMRKVFID----RAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75311-1", "uniprot_id": "GLRA3_HUMAN", "id": "O75311-1", "name": "Glycine receptor subunit alpha-3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSAR-------------SRSAPMSPSDFLDKLMGRTSGYDARIRP------------------------NFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE---YPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYN--------TGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-------------------------------------------------------------------------------------------------------------------------------------------HKELLRFRRKRKNKTEAF---------------------------ALEKFYRFSDMDDEVRESRFSFT-AYGMGPCLQAKDG----------------MTPKGPNHPVQVMPKSPD--------------------EMRKVFID----RAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q7Y2-1", "uniprot_id": "A0A8M9Q7Y2_DANRE", "id": "A0A8M9Q7Y2-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRKRLRSVAAWGFIAWEIGILLSLVASKEPESPR-------------RRAAPMSPSDFLDKLMGRTSGYDARIRP------------------------NFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE---YPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEKGPVQVADGLTLPQFILKDESDLRYCTKHYN--------TGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-------------------------------------------------------------------------------------------------------------------------------------------HKELLRFRRRRKKSGKTFDQTFDEELAESLRRINGSRS-AEPVYGSMGQLDQTNDMEEEVRESRLSFTPNAGKDGAVPKTAN----------------NAATTPSEPAVAPGKSHE--------------------EMRKLFID----RAKKIDTVSRAGFPLAFLFFNIFYWVLYKILRHEDVHKP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94900-1", "uniprot_id": "GLUCL_DROME", "id": "Q94900-1", "name": "Glutamate-gated chloride channel", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSGHYFWAILYFASLCSASLANNAK-------------INFREKE-KKVLDQILG-AGKYDARIRPSGI---------------------NGTDGPAIVRINLFVRSIMTISDIKMEYSVQLTFREQWTDERLKFDD---IQGRLKYLTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTL-EKFLTDYCNSKTN--------TGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRS-------------------------------------------------------------------------------------------------------------------------------------------GSNKANMHKENMKKKRRD--------------------------LEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEK----------------RLQCEVHMQAPKRPNCCK--------------------TWLSKFPTRQCSRSKRIDVISRITFPLVFALFNLVYWSTYLFREEEDE-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDU9-1", "uniprot_id": "Q9VDU9_DROME", "id": "Q9VDU9-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVFQIIILVICTICMKHY-------------AKGEFQQSLAITDILPEDIKRYDKMRPP------------------------KKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPEN--MTQEYRLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENIELPQVALIRNETAD-CTQVYS--------TGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSD-------------------------------------------------------------------------------------------------------------------------------------------TPIPKPMAYPPKPVAGDGPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIEKIFDEMTKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPK--------------------PKLTPAQER-LKRAIYIDRSSRVLFPALFASLNGIYWCVFYEYL---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PI70-1", "uniprot_id": "M9PI70_DROME", "id": "M9PI70-1", "name": "", "aln": "MGCVFEAAKEQPHKPRSRQLRRNQCRGKAEKAAAGTRGKVAVRGNNDKPAEDIKIKDNYQQNHKTQTETQTEVAAVVAIATDAGAETETETEAEAQKEPATGPEHLKAAAQVLLTIRQARQENNKHSSSQVAETHKDEGEDALARQGSIVDTAAGRIGIDIAATTIQVAERHEDGQHWQQHNVRRRRRQPDPAAHPASITKLSAISLHFHALAALAKTLQKHEDLSPVQDRQPLAYRAWQEHPYAETQMPATMSAAIIANVGATAAATSAAAFQYLGQHYKHYSQSISFYAASSVLLMLCYLTTASTAAATQSETGALDKHPIHGIDWSKFDESSSDKEILDLLLEKKRYDKRLLPPVNDEDFCCGLQSPDMATNQNARRPHNRGTLTVNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGN---KSHYDFLNALHHHDSIWTPDTYFIMHG-DFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSW--------RGNYSCLQVELTFTRDRAYYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVTQRLPAVLSRIGVILASPLASAAATPAMSMMGGATPMSSGTPAASSSVATPGTPRITDPEEFFGGGMRWQEAHGGIIGAAVQNLRARSIKRKAARSPSTSISPHPSGRPTEHIYEEPGGSTSGVTSTKVKFKDELKEEQPEEAESSTKLRRSVATSTPALVVRIEAEIDPEAEDKPIQDMEMTERQLSLPLKPPRRKASRSNSPASVYSDAFENVEATPGEKRQNAGAPNEIVACTTCGGSNSPCTHSANNGCATETCFVQVRKKEPPHPIRVAKTIDVIARITFPTAYAIFLIFFFVHYKGFS---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4G1-1", "uniprot_id": "Q9W4G1_DROME", "id": "Q9W4G1-1", "name": "pH-sensitive chloride channel 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEWSLIISILLNCLYASASALDEDCP------------TLDDGDSLSQTQLLDRLTHGCRYDRLERPITYS-------------------ETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRRQPILGEEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQHCSTVLESWMYNTSELVLHWEQKRPITYDGALHLTEFVLQRSWSNETVINADLSDLRHGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFITLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIWRRKKSVPVKKLN---------------------------------------------------------------------------------------------------------------------------SKHILKSTLSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQVLDQQRTSRVVQKMDVNFVESAFGSMG----------SAQSTGAISAASSSQTLTNNNRTESAG------------HQEEIDLSGWTTLTPQEIAMWIDSRARFVFPLSFLVFNLFFWTFVYCI----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** * . * . : : . : : : : * ** : . :* *. :: : . : : .: : * * .: :* * * : * :: *. . . . *:::.:.. . : * :*. ::* ::* *:::**:. .*.*: :* :::*.: * :** ** .. : : * *:: :::*: :* : . . : ** :* ** : : .:: ", "identical_positions": 42, "similar_positions": 84, "identity": "4.2%" }, { "cls_id": "homologset.agr.RGD:621230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C1C8-1", "uniprot_id": "PNMA1_MOUSE", "id": "Q8C1C8-1", "name": "Paraneoplastic antigen Ma1 homolog", "aln": "MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDETEIEETLQAAMPQVSYRVLGRMFWREENAKAALLELTGAVDYSLIPREMPGKGGLWKVVFKPPTSDAVFLERLHLFLAREGWTVQDVARVLGFQNPAPAPGPEMPAEMLNYILDNVIQPLVESIWYKKLTLFSGKDIPGPGEETFDSWLEHSNEIIEEWQVSDIEKRRRLMESLRGPAADVIRILKTNNAAITTAECLKALEQVFGSVESSRDAQVRFLNTYQNPGEKLSSYVIRLEPLLQKVVDKGVIDKDNVNQARLEQVIAGANHSGALRRQLWLAGAEEGPAPNLFQLLVQIREEEAKKEEEEAEAALLQLGLEGHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8VHZ4-1", "uniprot_id": "PNMA1_RAT", "id": "Q8VHZ4-1", "name": "Paraneoplastic antigen Ma1 homolog", "aln": "MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDETEIEETLQAAMPQVSYRVLGRMFWREENAKAALLELTGTVDYSLIPREMPGKGGLWKVVFKPPTSDAEFLERLHLFLAREGWTVQDVARVLGFQNPAPAPGPEMPAEMLNYILDNVIQPLVESIWYKKLTLFSGRDIPGPGEETFDSWLEHSNEVIEEWQVSDIEKRRRLMESLRGPAADVIRILKTNNPAITTAECLKALEQVFGSVESSRDAQVRFLNTYQNPGEKLSSYVIRLEPLLQKVVDKGAIDKDNVNQARLEQVIAGANHSGALRRQLWLTGATEGPAPNLFQLLVQIREEEAKEEEEEAEAALLQLGLEGHF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8ND90-1", "uniprot_id": "PNMA1_HUMAN", "id": "Q8ND90-1", "name": "Paraneoplastic antigen Ma1", "aln": "MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDEAEIEETLQAAMPQVSYRMLGRMFWREENAKAALLELTGAVDYAAIPREMPGKGGVWKVLFKPPTSDAEFLERLHLFLAREGWTVQDVARVLGFQNPTPTPGPEMPAEMLNYILDNVIQPLVESIWYKRLTLFSGRDIPGPGEETFDPWLEHTNEVLEEWQVSDVEKRRRLMESLRGPAADVIRILKSNNPAITTAECLKALEQVFGSVESSRDAQIKFLNTYQNPGEKLSAYVIRLEPLLQKVVEKGAIDKDNVNQARLEQVIAGANHSGAIRRQLWLTGAGEGPAPNLFQLLVQIREEEAKEEEEEAEATLLQLGLEGHF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********************************:****************:********************:***: **********:***:******** ****************************:*:****************************:******:***********.****:**::*******:**********************:**.*************************::*************:*************:**.***********************:******:** ********************:*******:**********", "identical_positions": 324, "similar_positions": 26, "identity": "91.78%" }, { "cls_id": "homologset.agr.RGD:621231", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Y0-1", "uniprot_id": "KEG1_RAT", "id": "Q9Z2Y0-1", "name": "Glycine N-acyltransferase-like protein Keg1", "aln": "--------------------MFYIQSSEALQILKNSLRKHLPESLKVYGTVFHMNQG--NPFKLKAVVDKWPDFNTVVIRPQEQDMTDDLDHYNNTYLIYSKDPKHCQEFLGSSDVINWKQHLQIQSSQADLGKVIENLGATNLGKVKHKQCFLYMVSHTAKKLTPSLVDAKHLVVSSEKPTPFDHQLFKFARLDVKHAALVNSIWYFGGNEKSQKFIERCIFTFPSVCIMG-PEGTPVSWALMDHTGELRMAGTLPKYRHQNLIYHVAFHQVHTLEKLG-FPMYLHVDKVNLTIQRMSAVLGHVPMP---CTWNQWNWVPL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCY0-1", "uniprot_id": "KEG1_MOUSE", "id": "Q9DCY0-1", "name": "Glycine N-acyltransferase-like protein Keg1", "aln": "--------------------MFCLQSSQALQVLENSLRKHLPESLKVYGTVFHINQG--NPFKLKTLVDKWPDFNTVVIRPQEEDMTDDLDHYNNTYLVYSKDPKHCQEFLGSSEVINWKQHLQIQSSQSDLGKVIESLGATNLGKVKHKQCFLYMVCQTAKKLAPSLMDAKNLVVSRNKLTPLDQQLFKFASLDVTHAALVNSLWHFGGNEKSQKFIERCIFTFPSFCIMG-PEGTPVSWTLMDHTGELRMGGTLPKYRRQSLIYHVASQQIQTLEKLG-FPMYAHVDKANFTVQRMVGLLGQILLP---CTWNQWNCVPL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1P898-1", "uniprot_id": "A0A8M1P898_DANRE", "id": "A0A8M1P898-1", "name": "Glycine N-acyltransferase-like protein", "aln": "MRCTQHRQQTPSEAHEQRNLVMRQLTTEDLKNLEVDLKNYFPQSLQAYGSIVLRNRTGQRADPVIVLVDQWPEFRVLLIKPEYR---EKGDSFK-DMTVFSKNDDYLRDLLAQRDVIDWKKFICLA-AELKHEKIMEVVAENRGVPVKKEAVCHMLVLQDLSKLPAFDSLS-----------------LKISSLNESHLELVNSNWKFGCEDS-KVMIKNMIANFPSCCVLD-SDDQPVAWLLTYVSCALGILYTLPEHRGKGYAKALVTVMSKKLHSQG-CPVYCFTEEENQLSYRLFTSLGFTEEPDFRAAWYVFNDL-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B4A7-1", "uniprot_id": "A0A8M3B4A7_DANRE", "id": "A0A8M3B4A7-1", "name": "Glycine N-acyltransferase-like protein", "aln": "---------------------MIILTSEELKQAESVLKNFFPESIKVYGCIVNINRG--KPHNLEVIADLWPEFTVIICKPKVQGVKNREGDFN-IYSIYSKSKDSLKSFLDTPGVINKDAFTLLAGVDIRHLGAVQEFADQQGIPSKVQGVMNVLVLQDQQQLQFKDRHAG----------------LSFAPLSTAHAHLVNSTWKYGGDSSSYNSVLNYISHNPSLCVIEEGQTEPVSWLLVYPHAALGLLYTLPQHRCKGHARLLVSIMSKNLLEQG-HPVYCFVEEENKPSYKLFTSLGFQNSPDYRAVWFELNKQQVSDE------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJA0-1", "uniprot_id": "Q9VJA0_DROME", "id": "Q9VJA0-1", "name": "N-acetyltransferase domain-containing protein", "aln": "--------------MATVGQLTRITDVANLKDLQILYLKDWPSNCVGYFWLDNYLRW----MDQNPTLKHLNFYTLDN-DWRSDGLFILVHRYQLFFSNLSKQKTDLEVALK---QLDWSRGFKVSAIHEIHHKIYKQLALDLGLNMDREMNTIMYILNREEAERLQIQCPDG---------------YFLDKVRLEHADLINDLWSAR-HPGSLKLIQMLITYNTNVGLYEKELGSLCAWCLRLQSGFLGALEVLPTHQRRGLGLVVAAAISKAIATDLQQDITALVNINNSAACRVFEKLNFRLIQDEHYYWSMIKPAAGGQISWPCDE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ98-1", "uniprot_id": "Q9VJ98_DROME", "id": "Q9VJ98-1", "name": "N-acetyltransferase domain-containing protein", "aln": "-----------------MGTRLEVIGLKDIQEFQQLYKQNWPKYCQEYYCLDNFVEF----LKKQPHMRNIKMYTLDAKQARDEGLFVIVDRYQLFVGCLNNTNGLVGKALD---LLDWSSGLKCSSIPSRHIGALDSLVESKKLNLVYRDCTNLFFMKANDALKLKVEPPSG---------------FVLKSLSVADAPLVNAEWPNH-HEGSLFFVERQIRLCVSVGLYQEDTQELVAWCIRLQGGYLGALQVKDTHKRRGFGSVVTREIAYRLAVQG-HDVMALVGPSNKPSSEMFSKLGFQVID--QCYWLRTEPTGG-QFTWPEGE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q2PDV0-1", "uniprot_id": "Q2PDV0_DROME", "id": "Q2PDV0-1", "name": "", "aln": "-------------------MEPILIEKSQWPELRDLYANDR-TNLTGFDLIEYFLNY--IPLSTTESIKIYTTDTDWRTHGSYILIHYLENKAYIYMNTIKGTPEDLGKLLN---SLKLKVFHLICGYEERFKPLVEAYWLNLGQDLINLEHQGAIVYHLPSTEIPSWKPSLS-------------TSCKVAYITSNHAELVDKHWAYR-SADSITMIRGFMENNLAVGVFD-NQGEPLAWCLRSPHGSLSNLHVLSSHRRMGLGSLAVRFMANEIKLKG-SEVLATVVPENEGSQKMFEKLGFNNIN--KLYWAVIPCTL----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : . . * :. . . . : . . . : . *:: * : : : :* : * . :: . . : : . * .: *. * ", "identical_positions": 8, "similar_positions": 35, "identity": "2.42%" }, { "cls_id": "homologset.agr.RGD:621232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1N6P0-1", "uniprot_id": "A0A8M1N6P0_DANRE", "id": "A0A8M1N6P0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------MNRRLYPIS-------FFAFFVALLLFILKIASADLSYNIPEETKRHYVIANIAKDFKMDVKQLSARKARIDPEDSSKRYCDINPNTGDLFVAETIDREELCGSRMSCILNYELVLENPLDVHRIIFQIQDINDNTPRFPNERINFEIRESAVKGQRFRLDEAHDSDIGKNSINDYSLEKNEHFVLTVQ-TADEEKYAELVLEKELDREQQKEMDLILTATDGGLPQRSGTAVIHITVLDANDNVPVFDQPIYKVTLAENTPSGTDIIRVSATDADEGPNGEVTYEFSRISDK-TAKLFSIDKTTGQILVKGEIDYESEKNYELGIQAKDASGLASIAKVIIDITDVNDNPPRIILKSLNNPIPENSEPGAEVGIINVQDKDSGENRQIRCSVQQNVPFKLNPSVKNYFSLVTTKALDREKESDYNITITATDGGSPPLSTSMTIHLFVSDVNDNPPVFEQQAYSAYINENNKADTSVCSVSANDPDWRQNGTVLYSLVPSEVSGVPVSSFLSINGDTGVIHAVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQILYPVP-DGKTLMTEMVPKATLSGSLVSKVIAVDADSGQNAWLSYQILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDNAQPSLSTTCVVNLLISDNLSEVP-ELKDMS-YEDN-NSKLTSYLIIALVSVCTFFLTFIILMLAVKFCHRRKPRLLFDGAVAVPSAYLPPNYADVDGAGTLRSSYNYDAYLTTGSRTSDFKFVSSY-NENTLPASGTLNKEHNIHFGSSIITLDVTGDKVE--QKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEA---------------TATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6A8-1", "uniprot_id": "A0A8M1N6A8_DANRE", "id": "A0A8M1N6A8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------MEYALFWGR-------FFACFVAVILLLPITVCADLNYNIPEETKSQYVIGNIAKDLGIDVKQLSARKSRIDTEDISKRYCDINMKTGDLIVAETIDREELCGSRMSCFLNYELVLENPLDVHRIIFQIQDINDNAPRFPNERINFEITESADKGQRFRLHEAHDSDIGRNAVNGYLLEKNNHFYLNVHDTAYGGKYAELVLEKELDREQQKEMDLILTATDGGSPQRSGTAVIHITVLDANDNVPVFDQPVYKVTLAENTPSGTEIIRVSATDADEGPNGEVTYEFSRISDK-ASKQFSIDKKTGQILVTEKIDYESEKNYEIGIHAQDGSGLASTATVIIDITDVNDNPPRIILKSLNNPIPENSEPGAEVGIINVQDKDSGENRQIRCSVQQNVPFKLNPSVKNYFSLVTTKALDREKESDYNITITATDGGSPPLSTSMTIHLFVSDVNDNPPVFEQQAYSAYINENNKVGTSVCSVSANDPDWRQNGTVLYSLVPSEVSGVPVSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQILYPVP-DGKTLMTEMVPKATLSGSLVSKVIAVDADSGQNAWLSFQILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDNGQPSLSTTCVVNLLISDNLSEVP-ELKDMS-YEDN-NSELTSYLIIALVSVCTFFLTFIIMMLAVKFCHRRKPRLLFDGAVAVPSAYLPPNYADVDGAGTIRSSYNHDAYLTTGSRTSDFKFVSSY-NENTLQAGGSLKSVQSDSFGAHVVTLINTEEAEE--QKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEA---------------TATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6G0-1", "uniprot_id": "A0A8M1N6G0_DANRE", "id": "A0A8M1N6G0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------MAKTSKLCLG-------KWRLWITSLLFC--VTAADVRYSVPEETKTKFVIGNLSKDVNLDYNRLRFRKARLDYQG-DRRYCEIDLDSGNLFVSERIDREMLCGTASPCIMHFEFILENPLELHNIALEVQDVNDNPPVFPKGSIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYILSQNKHFVLDTK--SSKDRYVDIVLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDMNDNAPLFLQPLYNARLSENSALGTSVIKITATDEDEGANGEIKYYINHLSDN-TKQLFKIDENYGEISVIGQLDHEKASSYEVEVQAEDGGGQTGHCKVVIEIDDVNDNAPVISVKSLKNKIPENTTPGTEIAVINVKDQDSGENSRISCSISPNLPFQLQPYIKSYFILTTSSSLDREQIDNYNVTIIATDGGIPPLFSNISLNIQVSDVNDNSPRFELQSYFIYISENKQAGTSVCSVSANDPDWRQNGTVLYSLVPSEVNGVPMSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQILYPVP-DGKTLMTEMVPKATLSGSLVSNVIAVDADSGQNAWLSYQILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDNGQPSLSTTCVVNLLISDNLSEVP-ELKDMS-YEDN-NSKLTSYLIIALVSVCTFFLTFIILMLAVKFCHRRKPRLLFDGAVAVPSAYLPPNYADVDGAGTIRSSYNYDAYLTTGSRTSDFKFVSSY-NENTLPAGGILDKSK---IDFNMLRLSDVGECTE--QKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEA---------------TATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6D6-1", "uniprot_id": "A0A8M1N6D6_DANRE", "id": "A0A8M1N6D6-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------MKTMLDA-------MIQHSVLILTLLVYIARGQVSYSIPEEMAKGSMVGNIAQDLGLDLQRLKSGKARIFSRD-STEYIELNRNTGLLLIKEKMDRESLCAKTTPCALHLQMILDNPMELYTITVEITDINDNAPNFQKRDFKFEISESAMVGARFMLGKAFDPDVGTNSLQSYSLKPTDKFRLELQSQADGSKNVEMILQKALDREMQSSFTLLLEAFDGGDPVLSGTVQIHIAVLDINDNAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNSEVTYYISDTMDSVMADMFLVNEQTGELILNGHFDYEKVSHYELTIHAKDQGGLSNACKVIIDVLDVNDNSPSINILSSSHSVSEGSKFGTVIAMLNVDDLDSGASGQVQCVMSEEIPFVIKSQSSNFFSLQTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQISDVNDNPPVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQNARVSYILEDSTVSGVSVSSYVSVHPDSGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQVLYPVQ-TGTSVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEVLSEFTDFT-HEKQYNDSLTFYLVLALAAVSFLFITCVVVIISVKIYRWRQSRFLYQSNLPVIP-YYPPHYADTGVTGTLPHGYNYEVCMTTDSRKSDCKFSTLG-GQNVLVVDPSFAETMKHTIKKNSS-IDDLQSTES--QKPPNTDWRFPPNQRPGPSG------------------AGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANASEA---------------TATLGPRYNLQYGPDYRQNVYIPGSTATLTANPQQQVLQQALPPPQALPPTEAPKAAQTPASKKKPTKKDKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1N6Q0-1", "uniprot_id": "A0A8M1N6Q0_DANRE", "id": "A0A8M1N6Q0-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MAFFV-------MWHGAVFFMILSRYAVKGQISYSIPEEIPKGSIVENNSQGLGLDLKRLNSGKARIFAGD-NRRFVGLNKEKGILLTEEKIDREALCAKTTPCASHLQLILENPMQKYDVTVEIIDINDNAPSFPKGEIRFEISETAVTGARFMLENPIDLDVGTNSHLSYSLKPTDNFILSSQGQTDGDKNMEMVLQKALDRENKEKLSLMLTAVDGGEPSLTSTVRIHVTVLDANDNPPVFSQRVYKATFAEITPKDTVIASVSASDADEGSNAIITYYMSSTGD--VNDLFTVDTRSRDIRLKGSADFEKASRYQFNIQARDQGGLSDSCKVIIDLTDINDNKPIISIVSMSNSISEQSRPGTVVAMLNVNDFDSGMNGRVHCYRNDNIPFTIAS-SSSFFSLQTEQELDREKEAEYNISVICSDEGVPALSSSVSLRVQISDVNDNAPVFEKSNYEAFVVENNTPGLSIFTVKASDADWNQNARVSYILEDSIVNGVSISSYVSVHPESGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDHNDNAPQVLYPVQ-TGASVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEVLSEFTDFT-HEKQYNDSLTFYLVLALAAVSFLFITCVVVIISVKIYRWRQSRFLYQSNLPVIP-YYPPHYADTGVTGTLPHGYNYEVCMTTDSRKSDCKFSTLG-RQNVLVVDPSFTETMQHTIKKKCS-IDGLRITKS--QKPPNTDWRFPPNQRPGPSGQHRFHTLQQRWTPYEKSRAGARPEEAGAGAGVIAGTGPWPNPPTEAEQLQAMMAAANE-----------------------ERNTHRFETSGRK------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9Y5G6-1", "uniprot_id": "PCDG7_HUMAN", "id": "Q9Y5G6-1", "name": "Protocadherin gamma-A7", "aln": "---------------------------------------------------------------------------------------------------------MAAQPRGGD------YRGFFLLSILLGTPWEAWAGRILYSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRG-RTQLFALNQRSGSLVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITP-KLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLEPSDGPYNYDLTLYLVVAVATVSCVFLAFVLVLLALRLRRWHKSRLLQASEGGLAN-VPTSHFVGMDGVQAFLQTYSHEVSLTADSRKSHLIFPQPN-YVDMLISQESCEKNDSLLTSVD--FQECKENLPSIQQAPPNTDWRFSQAQRPGTSG-----------------------SQNGD------DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN---------------AAGKRDGKAPAGGNGNKKKSGKKEKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y5H2-1", "uniprot_id": "PCDGB_HUMAN", "id": "Q9Y5H2-1", "name": "Protocadherin gamma-A11", "aln": "---------------------------------------------------------------------------------------------------------MANRLQRGDR-----SRLLLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRG-KTQLFAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDNAPSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISSGTRVLMVNATDPDEGINGEVMYSFRNMES-KASEIFQLDSQTGEVQVRGSLDFEKYRFYEMEIQGQDGGGLFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKSRLLQASEGGLAG-MPTSHFVGVDGVQAFLQTYSHEVSLIADSQKSHLIFPQPN-YGDTLISQESCEKSEPLLIAEDSAIILGKCDPTSNQQAPPNTDWRFSQAQRPGTSG-----------------------SQNGD------DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN---------------AAGKRDGKAPAGGNGNKKKSGKKEKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6G1R8-1", "uniprot_id": "A0A8I6G1R8_RAT", "id": "A0A8I6G1R8-1", "name": "", "aln": "MREGAAERRRGHRRPMLLPFLLPLFCPALSEQIRYKIPEEMPTGSVVGNLAKDLGFGVQELPTRKLRISSEKPYFTVSSESGELLVSSRLDREQICGKKLVSKQRGAKKMREGAAERRRGHRRPMLLPFLLPLFCPALSEQIRYKIPEEMPTGSVVGNLAKDLGFGVQELPTRKLRISS---EKPYFTVSSESGELLVSSRLDREQICGKKLVCSLEFEAVAENPLNFYHVSVELEDINDHTPKFAHTSFELQISESAQPGTRFILEVAEDADIALNSLQNYKLSLSPSFSLVNKEKQDGRKYPELVLEKTLDREQQSYYRLVLTALDGGDPPLSSTTELRIQVTDANDNPPVFDQEVYRVRLPENVPPGTTVARVTATDKDEGVNSEITYSFH-----RAGQVFGLNSNSGEITTQRTLDFEETKEYSIVVEARDGGGLVAQCTVEINIQDENDNKPEITVHSLLETIPENAPPGTLISLIKIHDRDSGENGEVNCRLDSEAPFKIISSSKNSYKLVTDRTLDRELTPEYNVSIMATDGGKPPLSSSTKVTLHVGDVNDNAPLFHQASYLVYIAENNPPGASIAQVSASDPDLGSNGHVSYSIIASDLEPKSLWSYVTVNAQSGVVFAQRAFDHEQLRSFQLTLQARDQGSPALSANVSMRVLVGDRNDNAPRVLYPALEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGEKDAARQRLLVGVRDGGQPPLSATATLLLVFADSLQEALPDLSDRSLPPDPQ-AELQFYLVVALALISVLFLLAVILAIALRLRHSSSPSAWNCFQPGFCS-ESKPVVFPNYSEGTLPYSYNLYGAHAGKTECNFLKCSEPLSSGQGLLCPESSGALFPLCDSSE------PTSHPEPPQAPPNTDWRFSQAQRPGTSG-----------------------SQNGD------ETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGTGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTN---------------AAGKRDGKAPAGGNGNKKKSGKKEKK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *.:.** .: : ::.. : ..* *: :. .* *. :*** :* * . : : :: :. : : .:: *:**: * * ...:: * : * :: * . * *:. *: * *. . * * : : :::*: **** . *:* * *** * ..:. :.: * * **: *:* *.. .* . .: : : * * *** *. : * : . * :: :: *.*. *.. :...* * .: * : * *** * : : * : * : *: :.:: :.* *** . .: * . ** : . : * * **** **::: .:* * *.* . : : :.* ***.* * * :: **: . *: *.* * * .*. : * : . :. .: *::::: ::*:: : ::**:* ::.: . : *:* *.*.**:*::: : : *.***.*.:***. . : ::.*::: * **::*:*** ***:*****: : ::.: .** :* .**::* * : : * :* * : *.* .**. *:. : : .:*.: *. :: . .* **::*:. :. .*: ::: ::::: : .. . . :: *. :. . : * . * ********. ****.** .: * **.*** ::* ****: *: : . :. .. *: ", "identical_positions": 192, "similar_positions": 260, "identity": "17.57%" }, { "cls_id": "homologset.agr.RGD:621233", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47902-1", "uniprot_id": "CDX1_HUMAN", "id": "P47902-1", "name": "Homeobox protein CDX-1", "aln": "-----------------MYVGYVLDKDSPVYPGP----ARPASLGLGPQAYGPPAPPPAPPQYPDFSSYSHVEPAPAPPT-AWGAPFPAPKDDWAA-----------------AYGPGPAAPAASPAS------------------------LAFGPPPDFSPVPAPPG---------PGPGLLAQP--LGGPGTPSSPGAQ-----------------------------------------RPTP-----YEWMRRSVAAGGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKK------------------------KQQ-----QQQ---PPQPPMAHDITATPAGPSLGGLCPSNTSLLATSSPMPVKEEFLP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P18111-1", "uniprot_id": "CDX1_MOUSE", "id": "P18111-1", "name": "Homeobox protein CDX-1", "aln": "-----------------MYVGYVLDKDSPVYPGP----ARPSSLGLGPPTYAPPGPAPAPPQYPDFAGYTHVEPAPAPPP-TWAAPFPAPKDDWAA-----------------AYGPGPTASAASPAP------------------------LAFGPPPDFSPVPAPPG---------PGPGILAQS--LGAPGAPSSPGAP-----------------------------------------RRTP-----YEWMRRSVAAAGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKK------------------------KQQ-----QQQPLPPTQLPLPLDGTPTPSGPPLGSLCPTNAGLLGTPSPVPVKEEFLP-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05095-1", "uniprot_id": "CDX1_RAT", "id": "Q05095-1", "name": "Homeobox protein CDX-1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKK------------------------KQQQQQQQQQQPMPPTQLPLPLDGTPTPSG-HPGSLCPTNAGLLGTPSPVPVKEEFLP-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P09085-1", "uniprot_id": "CAD_DROME", "id": "P09085-1", "name": "Homeotic protein caudal", "aln": "MVSHYYNTLPYTQKHSAANLAYASAAGQPWNWTPNYHHTPPNHQFLGDVDSSHAAHHAAAAHQMYYNSHHMFHSAAAASAGEWHSPASSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQ-PGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKAKLEPGLHLSHSLAHSMNPMAAMNIPAMRLHPHLAAHSHSLAAVAAHSHQLQQQHSAQMSAAAAVGTLSM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **************.********: ************* .*.*:***************** *** * : .:. . : . : .. .. . : :.: . . : :.. ", "identical_positions": 58, "similar_positions": 28, "identity": "13.55%" }, { "cls_id": "homologset.agr.RGD:621234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESV7-1", "uniprot_id": "Q9ESV7_RAT", "id": "Q9ESV7-1", "name": "", "aln": "------MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPP-----------------------QYPDYGGYHVAAAAAA----------------------------------AANLDSAQSPGPSWPTAYGAPLREDWNGYAPGG-AAAANAVAHGLNGGS--------------------PAAAMGYSSPAEYHAHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLS----PSGQRRNLCEWMRKPAQPSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKL---------------QQQQQQQP--PAPPPPQPSQPQSGALRSVPEPLSPVTSLQGSVPGSVPGVLGPAGGVLNSTVTQ------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43241-1", "uniprot_id": "CDX2_MOUSE", "id": "P43241-1", "name": "Homeobox protein CDX-2", "aln": "------MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPP-----------------------QYPDYGGYHVAAAAAA----------------------------------TANLDSAQSPGPSWPTAYGAPLREDWNGYAPGG-AAAANAVAHGLNGGS--------------------PAAAMGYSSPAEYHAHHHPHHHPHHPAASPSCASGLLQTLNLGPPGPAATAAAEQLS----PSGQRRNLCEWMRKPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHFSRYITIRRKSELAATLGLSERQVKIWFQNRRAKERKIKKKQQ---------------QQQQQQQQQ-PPQPPPQPSQPQPGALRSVPEPLSPVTSLQGSVPGSVPGVLGPAGGVLNSTVTQ------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99626-1", "uniprot_id": "CDX2_HUMAN", "id": "Q99626-1", "name": "Homeobox protein CDX-2", "aln": "------MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPP-----------------------QYPDYGGYHVAAAAAA----------------------------------AANLDSAQSPGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGS--------------------PAAAMGYSSPADYHPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLS----PGGQRRNLCEWMRKPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKL---------------QQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVPGSVPGVLGPTGGVLNPTVTQ------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09085-1", "uniprot_id": "CAD_DROME", "id": "P09085-1", "name": "Homeotic protein caudal", "aln": "MVSHYYNTLPYTQKHSAANLAYASAAGQPWNWTPNYHHTPPNHQFLGDVDSSHAAHHAAAAHQMYYNSHHMFHSAAAASAGEWHSPASSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKAKLEPGLHLSHSLAHSMNPMAAMNIPAMRLHPHLAAHSHSLAAVAAHSHQLQQQHSAQMSAAAAVGTLSM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* .:..: . : . * :*: . :** * .: :* ****:* *. .**.* ..* * *** :: *. * *.....*. . :**. ..:. ***. . **** * :: : .. :. * .*. . :.:* .. .: :**:*** : . **************.********: *********:*** **.******************* :** * : : * .:. . ..: :: * : . .: . *:..* . : : : :* ", "identical_positions": 106, "similar_positions": 91, "identity": "24.82%" }, { "cls_id": "homologset.agr.RGD:621235", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q803Q2-1", "uniprot_id": "NDL1B_DANRE", "id": "Q803Q2-1", "name": "Nuclear distribution protein nudE-like 1-B", "aln": "MDTEMMPKFSSKDEEIDYWKCLSLKYKKSCHDAQEELQEFQEGSRELEAELEAQLGQAEHRIRDLQSENQRLKSEVDILKEKLEQQYAQSYKQISMLEDDLLQTRGIKEQLHKYVRELEQANDDLERAKRATITSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERTSDVTRMSAPSSPTLDIDKTDSAVQASLSLPATPVGKTMEHPFIGTKALTNGCGNGSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQAARKNYTT--GNGNLINSNATKFSHSLHTTYFDKT-TMNGLDPGALSAAIASPRAVSPPGLLPLSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7SXI6-1", "uniprot_id": "NDL1A_DANRE", "id": "Q7SXI6-1", "name": "Nuclear distribution protein nudE-like 1-A", "aln": "MDADMIPKFTTKEEEIDFWKALSLKYKKSYKEAQEELLEFQEGSRELETELETQLGQAEHRIRDLQADNQRLQHELDSLKEKLEYQYAQSYKQISVLEDDLSQTRGIKEQLHKYVRELEQANDDLERAKRATITSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRDTRSEVTRMSAPSSPTPDNDKTDSAVQASLSLPATPLSKNLDNAFTSQTVLANGSTN-AALTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQAARKNYVTN-VNGNLINGDISNYSHSLHTSYFDKARTVNGLDPGDGTHITAPPRSNSPSGLV-LSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q78PB6-1", "uniprot_id": "NDEL1_RAT", "id": "Q78PB6-1", "name": "Nuclear distribution protein nudE-like 1", "aln": "MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENSFPSPKAIPNGFGT-SPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYVPGSVNCGVMNSNGPECPRSGRATFFHKG-AVNGFDPAPPPPGLGSSRPSSAPGMLPLSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERR1-1", "uniprot_id": "NDEL1_MOUSE", "id": "Q9ERR1-1", "name": "Nuclear distribution protein nudE-like 1", "aln": "MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENSFPSPKAIPNGFGT-SPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYVPGSVNCGVMNSNGPECPRSGRATFFHKG-AVNGFDPAPPPPGLGSSRPSSAPGMLPLSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZM8-1", "uniprot_id": "NDEL1_HUMAN", "id": "Q9GZM8-1", "name": "Nuclear distribution protein nudE-like 1", "aln": "MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFGT-SPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNGTKFSRSGHTSFFDKG-AVNGFDPAPPPPGLGSSRPSSAPGMLPLSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VT70-1", "uniprot_id": "NDE1_DROME", "id": "Q9VT70-1", "name": "Nuclear distribution protein nudE homolog", "aln": "--MESPPMFNSVEDECRYWKERSKQYHKEWTDVKQEYDEFVEQSREMEIEMDATLDQKQSIIKDLTAKLTMFERENESLKLKLESHGID----MSNMEKQLETVKKDRDTMKVYLRQLEQKNDDLERAHRILNESIENFEKMLDQAYEKNALLELEVDEKGLLQEKLQRLMDETRDLKQELNVKSRFTPVVNGTSVPTAN-DTNTVNSSMNSSASLPNGIVANGELVKHDN------------AVATRATSVSVNALNGSLVNRNEYNQQHSLKSDGDETEDVPREWSANAAATPLLP--AIHTSGAGRTALLLAGCRVVWILQFSVIHKPQIRNPIT---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *.: .:* :** * :*::. :.::* ** * ***:* *::: * * : :** :. :: * : ** *** : : :* :*.:* .: :: :: *:*:*** *******:* *:*:**: *:** *:**:** *:*** * .:*** **:***:*** *:. *.. :: .:.. * :. :*::::* *** :.: . . .::. * ::* :.. * : . :.: : : : : :.: . :: . . : ::: : : : .. : ", "identical_positions": 81, "similar_positions": 109, "identity": "23.34%" }, { "cls_id": "homologset.agr.RGD:621236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62671-1", "uniprot_id": "UBR5_RAT", "id": "Q62671-1", "name": "E3 ubiquitin-protein ligase UBR5", "aln": "----------MNKQAVKRLHMLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAFLLEDGRICRIGFSVQPDRLELGKPDNNDGSKLNSSSGTGRTSRPGRTSDSPWFLSGSETLGRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIID-ADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLPLERDSE------------------------LLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNPDKKNTPVQSPVSLGEDLQWWPDKD-GTKFTCIGALYSELVAVSSKGELYQWKWTESEPYRNAQNPSLHHPRATFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLEN-NLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGVQSLN-VRGGRQVCLRNNPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKSMEK-----------------------------ASKTIETKPESKQEPVKTEMGPPPSPAS-TCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGT-----------SSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIP---EKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQENNFPTSSVAFLGQNERSVAIFT----AGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPISSLGMGVHSLINLPANSTIKKKAAIIIMAVEKQTLMQHILRCDYEACRQYLVNLEQAVVLEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFA-----------ERLSAVEAIANAISVVSSNG-------PGNRAGSSSSRS----LRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPPIAPPSWVPDPPSMDPDGDIDFILAPAVGSLTTAATGGGQGPSTSTIPGPSTEPSVVESKDRKANAHFILKLLCDSAVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIAKAEVSGSEKEE--DVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRP-PRIRED--------------RNRKTASPD-DSDMPDHDLEPPRFAQLALERVLQDWNALRSMIMFGSQENKDPLSASSRIGHLLPEEQ-VYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASS---KKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGREEEQDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGHHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSS-SSQSDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALASAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRRATLLSARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTRELLELGIDNEDSEHENDDDTSQSATLNDKDDESLPAETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSAGSGKCLVEVTMDRNCLEVLPTKMSYAANLK-------------------NVMNMQN----------RQKKAGEDQSMLAEEADSSK------------------------------------------PGPSAHDVAAQLKSSLLAEIG----------------------LTESEGPPLTSFRPQCS-----FMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLSL-EVDRDRDLLIQQTMRQLNNHFG--RRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLDCIQNAN--KGTHTSLMQRLRNRGERDREREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGN---PSDDPDPLPAHRQALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVEEAMELIVAHGRENGADSILDLGLLDSSEKVQ-ENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAVDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVERMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TP3-1", "uniprot_id": "UBR5_MOUSE", "id": "Q80TP3-1", "name": "E3 ubiquitin-protein ligase UBR5", "aln": "MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAFLLEDGRICRIGFSVQPDRLELGKPDNNDGSKLNSSSGTGRTSRPGRTSDSPWFLSGSETLGRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIID-ADAMFSEDISYFGYPSFRRSSLSRLGSSR------ERDSE------------------------LLRERESVLRLRERRWLDGASFDNERGSTSKEGESNPDKKNTPVQSPVSLGEDLQWWPDKD-GTKFTCIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLEN-NLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKSMEK-----------------------------ASKTLETKPESKQEPVKTEMGPPPSPAS-TCSDASSIASSASMPYKRRRSTPAPREEEKVNEEQWPLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGT-----------STNTTCQNSSGPDADPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIP---EKTEILAVNVDSKGVHAVLKTGSWVRYCVFDLATGKAEQENNFPTSSVAFLGQDERSVAIFT----AGQESPIVLRDGNGTIYPMAKDCMGGIRDPDWLDLPPISSLGMGVHSLINLPANSTIKKKAAIIIMAVEKQTLMQHILRCDYEACRQYLVNLEQAVVLEQNRQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFA-----------ERLSAVEAIANAISVVSSNG-------PGNRAGSSNSRS----LRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPPIAPPSWVPDPPSMDPDGDIDFILAPAVGSLTTAATGSGQGPSTSTIPGPSTEPSVVESKDRKANAHFILKLLCDSAVLQPYLRELLSAKDARGMTPFMSAVSGRAYSAAITILETAQKIAKAEVSASEKEE--DVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRP-PRIRED--------------RNRKTASPE-DSDMPDHDLEPPRFAQLALERVLQDWNALRSMIMFGSQENKDPLSASSRIGHLLPEEQ-VYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASS---KKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSDQASSSSQSQSSYIIRNPQQRRISQSQPVRGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGHHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSS-SSQSDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNPQHQRAASTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSVMDSTEAQLRYGSALASAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRR-ATLLSARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTRELLELGIDNEDSEHENDDDTSQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSAGSGKCIVEVTMDRNCLEVLPTKMSYAANLK-------------------NVMNMQN----------RQKKEGEEQSLLAEEADSSK------------------------------------------PGPSAPDVAAQLKSSLLAEIG----------------------LTESEGPPLTSFRPQCS-----FMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLSL-EVDRDRDLLIQQTMRQLNNHFG--RRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLDCIQNAN--KGTHTSLMQRLRNRGERDREREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGN---PSDDPDPLPAHRQALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADSILDLGLLDSSEKVQ-ENRKRHGSSRSVVDMDLEDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95071-1", "uniprot_id": "UBR5_HUMAN", "id": "O95071-1", "name": "E3 ubiquitin-protein ligase UBR5", "aln": "MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAFLLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETLGRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIID-ADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLPLERDSE------------------------LLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDLQWWPDKD-GTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLEN-SLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEK-----------------------------ASKTTEAKPESKQEPVKTEMGPPPSPAS-TCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGT-----------SSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIP---EKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQENNFPTSSIAFLGQNERNVAIFT----AGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPISSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVVLEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFA-----------ERLSAVEAIANAISVVSSNG-------PGNRAGSSSSRS----LRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPPIAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKDRKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIAKAEISSSEKEE--DVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRP-PRIRED--------------RNRKTASPE-DSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQ-VYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASS---KKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSS-SSQSDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALASAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRR-ATLLSARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTRELLELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPTKMSYAANLK-------------------NVMNMQN----------RQKKEGEEQPVLPEETESSK------------------------------------------PGPSAHDLAAQLKSSLLAEIG----------------------LTESEGPPLTSFRPQCS-----FMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLSL-EVDRDRDLLIQQTMRQLNNHFG--RRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNAN--KGTHTSLMQRLRNRGERDREREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGN---PSDDPEPLPAHRQALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADSILDLGLVDSSEKVQQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NV16-1", "uniprot_id": "A0A8M1NV16_DANRE", "id": "A0A8M1NV16-1", "name": "E3 ubiquitin-protein ligase UBR5", "aln": "MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNCNSHPHLIPLEQAKLKQCVVGPNHAGFLLEDGRICRISFAVQPDRLELGKPDGNDGSKLSSVSGAGRSSRPGRTSDPPWFLSGSDTLGRLAGNTLGTRWSSGVNGGGGGSSGRSSTAARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIID-ADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLPLERDSE------------------------LLRERESVLRLRERRWLDGASFDAERGSTSREGEPSLDKKSVPLQSPVTLGEELQWWPDKDYVTKFVSIGALYSELVAVSTKGELYQWKWNEPEPYRNAQNPSIHHPRVPFLGLTNEKITHLSANSIRATVATENNKVATWVDETLSTVAAKLEHGAQTFPELQGERIVSLHCCALYTCAQLEN-SLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSIPNITVGTQVCLRNNPLYHAGAVAFSVNAGIPKVGVLLESVWNMNDSCRFQLRSPESLKNMEK-----------------------------NTKTQETKTESKPELVKTEMGPPPSPAS-TCSDTSSIASSASLPYKRRRSTPAPKEEEKVNEEQWPLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGT-----------SSSVSSQSAAPTDSDPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIP---EKAEILAVNVDSKGVHAVLKTGSWVRYCVFDLATGKAEQENHFPTSNLAFLGQSERNVAIFT----AGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPIASLGMGVHSLANLPSNSTIKKKAAIIIMAVEKQTLMQHVLRCDYEACRQYLISLEQAMLLEQNPHALDTLLGHRCDGNRNVLHACVSVCFPVSNKETKEEEEAERSERNTFA-----------ERLSAVEAIANAISVVSSNS-------SGNRTGSSSSRG----LRLREMMRRSLRAAGLGRHESGPSSSDHQDPVSPPIAPPSWVPDPPPMDPDGDIDFILAPAVGSLTTASTGTSQGPSTSTIPGPSSEPSVVESKDRKANAHLILKLMCDSIVLRPHLRELLSAKDARGMTPFMLAVSGRAYPAAITVLEAAQKIAKGEPGLGEKEDTASVFMEMICPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKAARLDLLYRLLTTTNLVTTPNSRGEHILLFLVQTVARQSVEHCQYRP-PRIRED--------------RNRKAASAE-DSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIAHLLPEEQ-MYLNQQSGTIRLDCFTHCLIVKCAPDITFIDTLLGTLVKELQNKYTPGRREEAINVTRRFLRSVARVFVILSVEMASS---KKKNNFIPQPIGKCRRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAVQGSEELFSVEPLPPRPSPDQSSSSSQSASSYIIRNPQPRRSSQSQTARGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDDQEEQGEENAEAEGQHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSS-SSQSDDVDQETFLLDEPLERTTGSAHANSAAQAPRSMQWAVRTTPSQRSGGGAPSSSSAPAASSTGLIYIDPSNLRRSSAISTSAAAAAAALEASNSSSYLTSASSLARAYSIVIRQISDLMSLIPKYNHLVYSQYPAAVKLTYQDAVNLQNFVEDKLIPTWNWMVSIMDSTEAQLRYGSALSSAGDPGHPSHPLHASQHAGRRERMTAREEASLRTLEGRRRAATLLTARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNLQTTLDTTQIDRKRNRELLELGLDNEDSEHENDEDTNQSSTLQDKDEEPVPAETGQHHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSYMASKGLTDLTVDMNCLQILPTKMSYSANMK-------------------NVMSMES----------RQR-GGEEQPVAEQEMDVSK------------------------------------------PGPSPHDLAAQLKSSLLAEIG----------------------LTESDGPPLPTFIPHCS-----FMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNLQSRDLAL-EVDRDREQLIQQTMRQLNAHFG--RRCTTTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNDKLPNLDCVQSVS--KGMQANLMQRLRNR---DRERER-----RSGGLRAASRRDRDRDSRRQLSIDTRPFRPASEGN---PSDEPEPLPAHRQALGERLYPRVHAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVEEAMELLITHGRENGADSILDLGLLDTPEKAQQENRKRHGSTRSVVDMELDDPDDGDDNAPLFYQPGKRGFYSPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLIRHSQTEEAEAVFAAMDLAFAIDLCKEEGAGQVELLSGGVNMPVTPLNVYEYVRRYAEHRMLVVAEQPLHAMRKGLLDVLPKNALEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P51592-1", "uniprot_id": "HYD_DROME", "id": "P51592-1", "name": "E3 ubiquitin-protein ligase hyd", "aln": "MVSMQFVLQPLPGSDDQFIERIREVSDKVNRFGYGSHRIFEQLKIP-VKEVVIGPAHIGVLLEDGKAFRVSFSINSEKLDLTKSD----AKCSTSGGSGTASASKAPSS-------SRPMARSRARLLRATGRSNSTGQGSGS------------RSTGVIIGGSTS------SRPLVTVPATYVPEELISQAEVVLQGKSRNLIIRELQRTNLDVNLAVNNLLSRDDEEAEDTEEGADN-YVP-EDLISLLDNGFSGDNNSVIIDPSDGLFSEEIFSN-YSSIRNLLFDRIRSERSNANANAADSNQSTTRSTSSGTALTGNSGLSAQISVNADREAFSRWRDRQYYGPRRWISKDDYTWEKDADSKKKEPSPMLSPIWISEELQPWPEKS-SVRFKTIGALYSEFIALSESGDLYQWRWSDAEPYK-SETENVYHPKTVSLNIV-ERVELISANFIRCSVVTETNRVATWMDEQLGYIGAKLEHSCCAFNEFISDSITKIYVCSLYTVVKTESNNIYWWGVLPFDQRRFLWDKFRTKTKKPFKVVAT----DINVGAQVIMKKCPMYQSGSIGFTCSNGVPKVGQLLNSVWTFTDVCRMKIININTNSGVDKSQAAGNNLNAHGITPDKDLPKSTAMPSTGSSKNGQSFSNSKESTDRIDMPPPPSPASSTCSDTGSVTSHKRTKRATTKEDSNAPQEGRKDEELWEVKDVVFVEDKVG-PVGKVLKVDGDFVAVRFPAINAAAVAAAAAATSSTSNTASTSKEEGKEDDWQQCRLLRREDVQIFRTAMSTRGPDWLQKQPKKINVGGDAAGAQILTLAVDSRGIHVIKKVLGKIHYSLYNLYNCKQEQNCLFPTDCNSFIGSTPGNILMACNDDCSGNSSTIVLRDGNGALYPLAKDCLGSIKDPQWFDLPPVKSITMSTISLPAMLSGVNLKSKVCMTALLFDTQKLMPHILRCDVKNSFAALGRLER-----EDQADTALVVEERCDGARNIFHACVIMCAPSSNKDSPPDSPSGGVEKKSLVGLSVARSIPTVSTSAYVSSIAFGASASSSNENSSFATMSSSAAGSASSTSRDNRTNLRDMMNRLINSDQAEQSGSQPMATNNEDHAYIPWPAETPAASNLSASSSQNVSDSIEDDISKIIPSSS---QSSMLSNIKLGSP-TYTFDLAQRREHALTILQQMCVSPALRPYLCHMLSTKDAQGQTPFMLSVSCRAYEAGIILLNTILMLSEQDP---------QLKEAMIFPNGSPADQSPLHVICYNDTCSFTWTGADHINQNIFECKTCGLTGSLCCCTECARVCHKGHDCKLKRTAPTAYCDCWEKCKCKALIAGNLTKRFALLCKLVSCTDLVTKFNSKGESILLFLIQTVGRQIVEQRQYRFSVRVRNVSTAATGATGNNSVISNRKTSAAEIDNDMPDHDLEPPKFARKALERLLIDWNAVRSMIMSGAERGDVPNPAGSASENSNSEGFNMFIQTQHGSTLLDKFTHSLIVKCTSDH--LDTLLLTLVRELQNASVSNRSKEAEEVVRRFVRSVARVFVIFNLEKQPNPEKRKSHSSCNKYVQSCVKVFQTLHKISIEELCEVSEALIAPVRLGVVRPTAPFTMSSSNLD---NSDDLFSVDPLAP---SNVESPSEQ----ILVHDAGNDQSANFNIQQNYDVVAMETIRDASESEEVIN---REANSHNQDDELIENQRNEDGMQDDESDND-----FTFNDAETESDSDDNQSNQE---VQRSVQAGATVGSEN---DIGVLFLEDESGDSSAQEEDGSEDGESDDQSDEFNFNEQQLERRSTNSNAR-SDLAPQTMQWAIRSRDTARSSVRVPTG--------SNMVFIDPMALRRS-TVPASTTVTTPSIEP---HTMATTASNLARAFGITIRQISELISILS-YN--VLNDIETSLKIQNDEAIAVQAFVEKRLKATWDWMFTVMDGTEAQLKFGAYLTNYTDPNHPLHPLNLSAQASSSQTPAPATSSSVNGVN-------IMGS-----NSRRDFFTYCLSLMRSHTSEHRDALPVLDITALRHIAYVLDAFVYYMRNDSGFYDKQDTISGRINNLSPMTESYDTDD-ELANLEEFNADVQMSASSMPSGSQGT-RRHAFFARSESTLSLGCSAPEGFELPLDMAMPLADKPHLLQPNSKRQELFANLP--LLVTTNANNSGATNDGDGGSIFDYTPTRLGFSNSLKRNERVYETVPIDSSKTGDGNVTNKAEGSTDSNIYVQLKKKQGSDDFKSHKEADGNQSKYEKVVLMETDDSLPSTSKSTEALMATRPEVIIAPNKASVSPATAARSVIVLAGGSCLKTIDSDINNYSASNLSTAEQAKCDTQYQKSTSDHLLLFPARGSQFYQSNFSELPSWNFLLSRWKLTLDLFGRVFMDDVGMEHGSVLPELRGFPVKEMRFRRHMEKLRNGQQRDLVLCKLERNRESLIVQTFKELNTQFGNQSRRIQPPITFNRVKVTFKDEPGEGSGVARSFYTSIAEALLASAKIPNLESVQVGTNHSKYVVPFSSILRSRTVSGSSRDQSTLQRRGSNSKILWRSARER---KALNLDARPYTPPNSSDNATPESLNDHLSVHLQQIGERLYPKIHSINQTHAPKITGMLLEIPTPQLLSVISSDETLRQKVNEAIEIITFKQK--------------SETSAQSSQPK---KSPSVVVVDPVD----DDNEPLFYSPGKRGFYTPRQGFASFERINAFRNIGRLIGLCLLQNELLPLFLQRHVLKYILGRKIKFHDLAFFDPALYESFRQIIQNAQTKEGEETINRMELCFVIDLMKEEGCGNRELIPGGRDVAVTSSNIFEYVRRYTEYRLIKSQEKALEALKDGVFDVLPDNSMINLTAEDLRLLLNGVGDINVSTLISYTTFNDESSEGPDKLLKFKKWFWSIVEKMNIMERQDLVYFWTGSPALPASEEGFQPLPSVTIRPADDSHLPTANTCISRLYIPLYSSKSILRSKMLMAIKSKNFGFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :****:*:*::. .** : *: . :*: *:** * ..*****: *:.*:::.::*:* *.* :* .: .*:* :* . .*. * .:.* .. * : *. * *.** *.* ** * *:* .:**: :********:********.:*************************:.:* :: *.: *:* ***:**** .: . : ***** :*.:***:* *.*:*. :.*: *.* **: : :**:. * *:*:: . : : . * .:. . .*: *: **: :.*:** **:*. .:* *******::*:* .*:****:*.:.***: ::. .::**:. *.:. *:: :*** **.:*.**.*:****:** *. :.:**** . :: *: .: *..:: *:*** .: *. .:*****:**.**: : :* *:*.*** . .. : * ** ::: *:*::*::.*: . *:**** *::***.:.* **::: . :: ..::* :*. :: .:** . : :* ******* ****:.*::* :. . . :* : :** * :::****** . ********** :***:**. ::... :: : . .. *:***** :::*:.:*. :.: ** :*: ***: : ::**:: ***:*:*.: *. . ::*.:::* . * **: ***. :*:*. .: : :*:.*.*:******::**:****:*.*:**:*:****: *: *.. ** : :. .:*.*..: : .:.*.** *:**** : . * **: :: .: .**** **::**** :* * ***:: :. : *::::. . : *.:** . *. *** ... :**:.* . .**:**.* :.: : : . :::::* . * .. : ... . ... ::. : :..: .::: *.. *.* *. . ..: :*: :* **: :* * .*:*:* .:**:***:* **** :** *** *.* :*:: ::: : .: *: *.*: .*:***:*:* ***********:****:****:**** ***********************:**************:****: : *: ** :*:: *:*** **:** :****:***.** **: *** *:*: ***:::.: *.**********:**: ****:* ****::**** *::... * .*.* : .* :::: * *: ** ***.*****:.* :**** ***:**** ...* :** *. **:*********:.:* .. :*.:. : : .* :***:* ::****:*:*:**.***:*:.*******::*:.:* .*::****:**.* .: *.*.* ::::. : :: : :. : : : *. **:: * : *::::* *:: : :* :*:..::. : *******:.*:***: :*** :.**.*** .: .:* **:* ...:.:.*.* ..:*** .:* : :: *** : .::*. : **::****:*. *:. .*:. :.:::*** **** ::.:*::.::.::*. : *:**.****:.*.*****:*:.::. ** * .: :::*: ::*: :* :**.:* .**:**.::**.*****::*: *:. **.** ***: * ::. : :. .:*:. :: :: : .:* **:.*.*******..** *.*****: :*:*:***::*::*::: . : . * .. . : . *.:* * * :: . . :. .. . . * :.*.** **:* *** .*: **:** *:****:*******:::::**.. . * :: .. : . . :: **::.:: .:* ** . . :: *.:: :* : .: *..:. .: . .* * *. :* . * * .: * :. : * ::**.**:*:*:*******:*** * **:*.** ** *** :***.****** *.*** * :::*:*: ** **:::** :** * .*::.:**********************:**:*:*:. *:***:.:* . . . : . **.* . .*:: *... : * *:* : *.:*:**: *....: *.. : *..* * :******:::::: :.*.********:...*** :::*:::** :*:**:*:: : : : ..* .: * .: *** :: * *** ****.*******:** * : *:*.******::********* *: *:***:* :****:::**:*****.:***:**:* :*:.:.: .: *:*.*.:** **** *: **:..* ::.**. *::****:*:*:*:: *:.*.*::.*::****.*:: :*****:***:** *::**. ***:*:*****.*..:***:**:*******:*.: **********.**:**********:**:****.**.*************:******.**:.*:*:***:******", "identical_positions": 1112, "similar_positions": 941, "identity": "36.75%" }, { "cls_id": "homologset.agr.RGD:621237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25118-1", "uniprot_id": "TNR1A_MOUSE", "id": "P25118-1", "name": "Tumor necrosis factor receptor superfamily member 1A", "aln": "MGLPTVPGLLLSLVLLALLMGIHPSGVTGLVPSLGDREKRDSLCPQGKYVHSKNNSICCTKCHKGTYLVSDCPSPGRDTVCRECEKGTFTASQNYLRQCLSCKTCRKEMSQVEISPCQADKDTVCGCKENQFQRYLSETHFQCVDCSPCFNGTVTIPCKETQNTVCNCHAGFFLRESECVPCSHCKKNEECMKLCLPPPLANVTNPQDSGTAVLLPLVILLGLCLLSFIFISLMCRYPRWRPEVYSIICRDPVPVKEEKAG----KPLTPAPSPAFSPTSGFNPTLGFS-TPGFSSPVSSTPISPIFGPSNWH-FMPPVSEVVP-TQGADPLLYESLCSVPAPTSVQKWED--SAHPQRPDNADLAILYAVVDGVPPARWKEFMRFMGLSEHEIERLEMQNGRCLREAQYSMLEAWRRRTPRHEDTLEVVGLVLSKMNLAGCLENILEALRNPAPSS-TTRLPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22934-1", "uniprot_id": "TNR1A_RAT", "id": "P22934-1", "name": "Tumor necrosis factor receptor superfamily member 1A", "aln": "MGLPIVPGLLLSLVLLALLMGIHPSGVTGLVPSLGDREKRDNLCPQGKYAHPKNNSICCTKCHKGTYLVSDCPSPGQETVCEVCDKGTFTASQNHVRQCLSCKTCRKEMFQVEISPCKADMDTVCGCKKNQFQRYLSETHFQCVDCSPCFNGTVTIPCKEKQNTVCNCHAGFFLSGNECTPCSHCKKNQECMKLCLPP-VANVTNPQDSGTAVLLPLVIFLGLCLLFFICISLLCRYPQWRPRVYSIICRDSAPVKEVEGEGIVTKPLTPASIPAFSPNPGFNPTLGFSTTPRFSHPVSSTPISPVFGPSNWHNFVPPVREVVP-TQGADPLLYGSLNPVPIPAPVRKWEDVVAAQPQRLDTADPAMLYAVVDGVPPTRWKEFMRLLGLSEHEIERLELQNGRCLREAHYSMLEAWRRRTPRHEATLDVVGRVLCDMNLRGCLENIRETLESPAHSS-TTHLPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19438-1", "uniprot_id": "TNR1A_HUMAN", "id": "P19438-1", "name": "Tumor necrosis factor receptor superfamily member 1A", "aln": "MGLSTVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQ-IENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTTTKPLAPN--PSFSPTPGFTPTLGFSPVPSSTFTSSST-----YTPGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDS-AHKPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLLGCLEDIEEALCGPAALPPAPSLLR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. **.***.**** **:**:**** **** ********.:****** *.:*************** .***.**::* *. *:.*:****:*::*:****..***** *****.* .* ******::**:::* **. ***.:** *:**** :.*:*.*****.******* .**..**:***. ** ***** : **...:****:*******::***** :: *.*: ** :*:..:***:* ...* ** : ***:* *:***..**.****** .* : . *** : *.: * .* **.* *****:* :* . * * .::**** : :** *. * * *****:.*** *****:* :***:***:***:*********:**** :*******:* **:::* ** .*:* ****:* *:* .** . :. * *", "identical_positions": 270, "similar_positions": 109, "identity": "58.19%" }, { "cls_id": "homologset.agr.RGD:621238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80WY6-1", "uniprot_id": "TNR1B_RAT", "id": "Q80WY6-1", "name": "Tumor necrosis factor receptor superfamily member 1B", "aln": "MAPAALWVALVVELQLWATGHTVPAKVVLTPYKPEPGNQCQISQEYYDKKAQMCCAKCPPGQYAKHFCNKTSDTVCADCAAGMFTQVWNHLHTCLSCSSSCSDD-QVETHNCTKKQNRVCACNADSYCALKLHSGNCRQCMKLSKCGPGFGVARSRTSNGNVICSACAPGTFSDTTSSTDVCRPHRICS--ILAIPGNASTDAVCASESPTPSAVPRTIYVSQPEPTRSQPMDQEPGPSQTP--HIPVSLGSTPIIEPSITGGISLPIGLIVGLTTLGLLMLGLANCFILVQRKKKPSCLQRETMVPHLPDDKSQDAIGLEQQHLLTTAPSSSSSSLESSASAGDRRAPPGGHPQARVTAEAQGSQEACAGSRSSDSSHGSHGTHVNVTCIVNVCSSSDHSSQCSSQASTTVGDPDANPSGSPKDEQVPFSQEECPSQSQWETTETLQN--HDKPFPLGVPDVGMKPNQPGWYDQIAVKVP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25119-1", "uniprot_id": "TNR1B_MOUSE", "id": "P25119-1", "name": "Tumor necrosis factor receptor superfamily member 1B", "aln": "MAPAALWVALVFELQLWATGHTVPAQVVLTPYKPEPGYECQISQEYYDRKAQMCCAKCPPGQYVKHFCNKTSDTVCADCEASMYTQVWNQFRTCLSCSSSCTTD-QVEIRACTKQQNRVCACEAGRYCALKTHSGSCRQCMRLSKCGPGFGVASSRAPNGNVLCKACAPGTFSDTTSSTDVCRPHRICS--ILAIPGNASTDAVCAPESPTLSAIPRTLYVSQPEPTRSQPLDQEPGPSQTP--SILTSLGSTPIIEQSTKGGISLPIGLIVGVTSLGLLMLGLVNCIILVQRKKKPSCLQRDAKVPHVPDEKSQDAVGLEQQHLLTTAPSSSSSSLESSASAGDRRAPPGGHPQARVMAEAQGFQEARASSRISDSSHGSHGTHVNVTCIVNVCSSSDHSSQCSSQASATVGDPDAKPSASPKDEQVPFSQEECPSQSPCETTETLQS--HEKPLPLGVPDMGMKPSQAGWFDQIAVKVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20333-1", "uniprot_id": "TNR1B_HUMAN", "id": "P20333-1", "name": "Tumor necrosis factor receptor superfamily member 1B", "aln": "MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRL-REYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSD-QVETQACTREQNRICTCRPGWYCALSKQEG-CRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICN--VVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGS-TGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPG-VEASGAGEARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2L3-1", "uniprot_id": "A0A8M2B2L3_DANRE", "id": "A0A8M2B2L3-1", "name": "", "aln": "----MLILIARLLLLFMTVVWLMAEGKIPPPFRPEKEQCNNTTSEYYMKQLGLCCSRCKPGTRLSVQCSTASDTICEPCPDGMYSENMNHYPNCFKCPTCREEKGLMYGRNCSADTKAVCVCKPGMYCSKYGLSSACEECKKYKTCKPGEGAQRKGTPTGVVKCAPCPTGTFSDRSG-SEPCRPHTECEGSAVLRSGNSTDDTVCVVKPLKATPEIWPMNTISTSTVSVLSSDVKHSSTVTTN-----AQGTRSNPPPD-----YMTIIYITGAVVLVLLILVMTVVTCKLRERKAGLTKVPITDVNTVEQDPSQSS-TPDHQHLLHVDRTQTEPSMSSSDSQSQ---PDCGQSHSSSEWLERSSQDECPSVSSP---------------VLNLSITATFNCQLNPAATSCSIPINPSTLTPHAEALVPLSQEEVCTSSCQQE--------DGKEVLKSVQESGPFLY-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * : :. :. .*: ** . *** : :**::* ** . *..:***:* * . ::: * *:.* : . : : *: . : :*.*... **: .. *. * .* ** *. : .. * * .*..****: :. :: **** *. : .**:: *:**. . . : .: .. .. : .: :. . *. . . :.: *.* . * **:: :. : :* : * : : ::.: ::**** . :.:..*:.** * : * .:.:: . : .. . ::*:. :: ...* .. *:: :... . : **:*:** * : . * . .* : * ", "identical_positions": 78, "similar_positions": 144, "identity": "16.22%" }, { "cls_id": "homologset.agr.RGD:621239", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05504-1", "uniprot_id": "ATP6_RAT", "id": "P05504-1", "name": "ATP synthase F(0) complex subunit a", "aln": "-------------------MNENLFASFITPTMMGLPIVVTIIMFPSILFPSSERLISN-------RLHSFQHWLIKLIIKQMMLIHTPKGRT-WALMIVSLIMFIGSTNLLGLLPHTFTPTTQLSMNLSMAIPLWAGAVILGFRHKLKNSLAHFLPQGTPISLIPMLIIIETISLFIQPMALAVRLTANITAGHLLMHLIGGATLVLMDISPPTATITFI---ILLLLTVLEFAVALIQAYVFTLLVSLYLHDNT---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P00848-1", "uniprot_id": "ATP6_MOUSE", "id": "P00848-1", "name": "ATP synthase F(0) complex subunit a", "aln": "-------------------MNENLFASFITPTMMGFPIVVAIIMFPSILFPSSKRLINN-------RLHSFQHWLVKLIIKQMMLIHTPKGRT-WTLMIVSLIMFIGSTNLLGLLPHTFTPTTQLSMNLSMAIPLWAGAVITGFRHKLKSSLAHFLPQGTPISLIPMLIIIETISLFIQPMALAVRLTANITAGHLLMHLIGGATLVLMNISPPTATITFI---ILLLLTILEFAVALIQAYVFTLLVSLYLHDNT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P00846-1", "uniprot_id": "ATP6_HUMAN", "id": "P00846-1", "name": "ATP synthase F(0) complex subunit a", "aln": "-------------------MNENLFASFIAPTILGLPAAVLIILFPPLLIPTSKYLINN-------RLITTQQWLIKLTSKQMMTMHNTKGRT-WSLMLVSLIIFIATTNLLGLLPHSFTPTTQLSMNLAMAIPLWAGTVIMGFRSKIKNALAHFLPQGTPTPLIPMLVIIETISLLIQPMALAVRLTANITAGHLLMHLIGSATLAMSTINLPSTLIIFT---ILILLTILEIAVALIQAYVFTLLVSLYLHDNT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P00850-1", "uniprot_id": "ATP6_DROME", "id": "P00850-1", "name": "ATP synthase subunit a", "aln": "-------------------MMTNLFSVFDPSAIFNFSLNWLSTFLGLLMIPSIYWLMPS-------RYNIMWNSILLTLHKEFKTLLGPSGHNGSTFIFISLFSLILFNNFMGLFPYIFTSTSHLTLTLSLALPLWLCFMLYGWINHTQHMFAHLVPQGTPAILMPFMVCIETISNIIRPGTLAVRLTANMIAGHLLLTLLGNTGPSMSYI---LVTFLLM---AQIALLVLESAVAMIQSYVFAVLSTLYSSEVN---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P00854-1", "uniprot_id": "ATP6_YEAST", "id": "P00854-1", "name": "ATP synthase subunit a", "aln": "MFNLLNTYITSPLDQFEIRTLFGLQSSFIDLSCLNLTTFSLYTIIVLLVITSLYTLTNNNNKIIGSRWLISQEAIYDTIMNMTKGQIGGKNWGLYFPMIFTLFMFIFIANLISMIPYSFALSAHLVFIISLSIVIWLGNTILGLYKHGWVFFSLFVPAGTPLPLVPLLVIIETLSYFARAISLGLRLGSNILAGHLLMVILAGLTFNFMLINLFTLVFGFVPLAMILAIMMLEFAIGIIQGYVWAILTASYLKDAVYLH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : * : :.:. :: :::.: * . * . : : .. ::.:*: :* *::.::*: *: :::* : ::::: :* : * : :: ::* *** *:*::: ***:* : :. :*.:** :*: *****: ::.. : * : : : : :** *:.:**.**:::* : * : ", "identical_positions": 41, "similar_positions": 82, "identity": "15.83%" }, { "cls_id": "homologset.agr.RGD:621240", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P03930-1", "uniprot_id": "ATP8_MOUSE", "id": "P03930-1", "name": "ATP synthase F(0) complex subunit 8", "aln": "MPQLDTSTWFITIISSMITLFILFQLKVSSQTFPLAPSPKSLTTMKVKTPWELKWTKIYLPHSLPQQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11608-1", "uniprot_id": "ATP8_RAT", "id": "P11608-1", "name": "ATP synthase F(0) complex subunit 8", "aln": "MPQLDTSTWFITIISSMATLFILFQLKISSQTFPAPPSPKTMATEKTNNPWESKWTKTYLPLSLPPQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P03928-1", "uniprot_id": "ATP8_HUMAN", "id": "P03928-1", "name": "ATP synthase F(0) complex subunit 8", "aln": "MPQLNTTVWPTMITPMLLTLFLITQLKMLNTNYHLPPSPKPMKMKNYNKPWEPKWTKICSLHSLPPQS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*:.* * . : ***:: ***: . .: .****.: : :.*** **** *** * ", "identical_positions": 28, "similar_positions": 17, "identity": "41.18%" }, { "cls_id": "homologset.agr.RGD:621241", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUQ1-1", "uniprot_id": "ATS1_RAT", "id": "Q9WUQ1-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 1", "aln": "----------------------------------------MQPEVPLGSGKLKPCSDMGDIQRAAKFRSSQSAHMLLLLLASITMLLCVRGAHGRPTEEDEELVLPSLERARGHDS-TTLLRLDAFGQQLHLKLQPDSGFLA---PGFTLQTVGRSPGS--EAQHLDPTGDLAHCFYSGTVNGD------------------PSSAAALSLCEG--VRGAFYLQ--GEEFFIQPAPA-VATERLVPAEPKEESIAPPRFHILRRRRRGSGGAKCGVMDEETLPT-------SNSGRESQNTPDQWPLRNPTPQGAGKPTGPGSIRKKRFVSSPR-----------YVETMLVADQSMADFHG--------SGLKHYLLTLFSVAARFYKHPSIRNSISLVVVKILVIYEEQK--GPEVTSNAALTLRNFCSWQKQ-HNSPSDRDPEHYDTAILFTRQDLC------GSHTCDTLGMADVGTVCDP------SRSCSVIEDDG-LQAAFTTAHELGHVFNMPHDDAKHCASFNG-----VSGDSHLMASMLSSLDHSQPWSPCSAYMVTSFLDNGHGECLMDKPQNP----IKLPSDLPGTLYDANRQCQFTFGE--ESTHCPDAASTCSTLWCTGTSG-GLLVCQTKHFPWADGTSCGEGKWCVSGKCVNKT--------------------------------------DMKHFATPVHGSWGPWGPWGDCSRTCGGGVQYTMR----------ECDNPVPKNGGKYCEGKRVRYRSCNIEDCPDNNGKTFREEQCEAHNEFS-KASFGNEPTVEWTPKYAGVSPKDRCKLTCEAKGIGYFFVLQPKVVDGTPCSPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTCKKISGTVTST--------RPGYHDIVTIPAGATNIEVKHRNPRGSRNNGSFLAIRAADGTYILN----------------GNFTLSTLEQDLTYKGTVLRYSGS-------SAALERIRSFSPLKEPLTIQVLMVGHALRPKIKYTYFMKK----KTEPFNAIP--TFSEWVIEEWGECSKTCGSGWQRRVVECRDINGHPAS---ECAKEVKPASTRPCADLPCPRWQVGDWSPCSKTCG----------------------------------------------------------------------------------------------------------KGYKKRTLKCLSHDGGVLSNESCDPLK--KPKHYIDFCILTQCS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97857-1", "uniprot_id": "ATS1_MOUSE", "id": "P97857-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 1", "aln": "----------------------------------------MQPKVPLGSRKQKPCSDMGDVQRAARSRGSLSAHMLLLLLASITMLLCARGAHGRPTEEDEELVLPSLERAPGHDSTTTRLRLDAFGQQLHLKLQPDSGFLA---PGFTLQTVGRSPGS--EAQHLDPTGDLAHCFYSGTVNGD------------------PGSAAALSLCEG--VRGAFYLQ--GEEFFIQPAPG-VATERLAPAVPEEESSARPQFHILRRRRRGSGGAKCGVMDDETLPT-------SDSRPESQNTRNQWPVRDPTPQDAGKPSGPGSIRKKRFVSSPR-----------YVETMLVADQSMADFHG--------SGLKHYLLTLFSVAARFYKHPSIRNSISLVVVKILVIYEEQK--GPEVTSNAALTLRNFCSWQKQ-HNSPSDRDPEHYDTAILFTRQDLC------GSHTCDTLGMADVGTVCDP------SRSCSVIEDDG-LQAAFTTAHELGHVFNMPHDDAKHCASLNG-----VSGDSHLMASMLSSLDHSQPWSPCSAYMVTSFLDNGHGECLMDKPQNP----IKLPSDLPGTLYDANRQCQFTFGE--ESKHCPDAASTCTTLWCTGTSG-GLLVCQTKHFPWADGTSCGEGKWCVSGKCVNKT--------------------------------------DMKHFATPVHGSWGPWGPWGDCSRTCGGGVQYTMR----------ECDNPVPKNGGKYCEGKRVRYRSCNIEDCPDNNGKTFREEQCEAHNEFS-KASFGNEPTVEWTPKYAGVSPKDRCKLTCEAKGIGYFFVLQPKVVDGTPCSPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTCKKMSGIVTST--------RPGYHDIVTIPAGATNIEVKHRNQRGSRNNGSFLAIRAADGTYILN----------------GNFTLSTLEQDLTYKGTVLRYSGS-------SAALERIRSFSPLKEPLTIQVLMVGHALRPKIKFTYFMKK----KTESFNAIP--TFSEWVIEEWGECSKTCGSGWQRRVVQCRDINGHPAS---ECAKEVKPASTRPCADLPCPHWQVGDWSPCSKTCG----------------------------------------------------------------------------------------------------------KGYKKRTLKCVSHDGGVLSNESCDPLK--KPKHYIDFCTLTQCS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHI8-1", "uniprot_id": "ATS1_HUMAN", "id": "Q9UHI8-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 1", "aln": "----------------------------------------MQRAVPEGFGRRKLGSDMGNAERAPGSRSFGPVPTLLLLAA---ALLAVSDALGRPSEEDEELVVPELERAPGHGT--TRLRLHAFDQQLDLELRPDSSFLA---PGFTLQNVGRKSGS--ETP--LPETDLAHCFYSGTVNGD------------------PSSAAALSLCEG--VRGAFYLL--GEAYFIQPLP--AASERLATAAPGEKPPAPLQFHLLRRNRQGDVGGTCGVVDDEPRPTGKAETEDEDEGTEGEDEGAQWSPQDPALQGVGQPTGTGSIRKKRFVSSHR-----------YVETMLVADQSMAEFHG--------SGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQK--GPEVTSNAALTLRNFCNWQKQ-HNPPSDRDAEHYDTAILFTRQDLC------GSQTCDTLGMADVGTVCDP------SRSCSVIEDDG-LQAAFTTAHELGHVFNMPHDDAKQCASLNG-----VNQDSHMMASMLSNLDHSQPWSPCSAYMITSFLDNGHGECLMDKPQNP----IQLPGDLPGTSYDANRQCQFTFGE--DSKHCPDAASTCSTLWCTGTSG-GVLVCQTKHFPWADGTSCGEGKWCINGKCVNKT--------------------------------------DRKHFDTPFHGSWGMWGPWGDCSRTCGGGVQYTMR----------ECDNPVPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHNEFS-KASFGSGPAVEWIPKYAGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTCKKISGSVTSA--------KPGYHDIITIPTGATNIEVKQRNQRGSRNNGSFLAIKAADGTYILN----------------GDYTLSTLEQDIMYKGVVLRYSGS-------SAALERIRSFSPLKEPLTIQVLTVGNALRPKIKYTYFVKK----KKESFNAIP--TFSAWVIEEWGECSKSCELGWQRRLVECRDINGQPAS---ECAKEVKPASTRPCADHPCPQWQLGEWSSCSKTCG----------------------------------------------------------------------------------------------------------KGYKKRSLKCLSHDGGVLSHESCDPLK--KPKHFIDFCTMAECS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PWV9-1", "uniprot_id": "A0A8M9PWV9_DANRE", "id": "A0A8M9PWV9-1", "name": "", "aln": "------------------------------------------------MSFLRVVLSLAGFALCVNAAQSAWEESFVLPVR-----LDTQPGHTKQSREE--------------DSEKRIYRLDVFGKRMVLALEPDQTFLA---PGFVFQMVGKPETG--EFD----SAGEARCFFSGTVNGD------------------ELSSAAINLCKG--LHGGFSVG--GEEYFIQPEN-----STGAATDRDTHTIRRRTPGILAE----ESGSKCGVNEEEERVT-----------------------EKPHTTHSKPSESKAHHRSRRFVSTPR-----------YLEIMIVADQSMAEFHG--------AQLKPYLLTIMAVASRLYRHPTIHNSITLAVVKLLVVHDEEH--GPHVSTNAALTLRSFCQWQKQ-HNQPSDRHPEHYDTAVLFTRKDLC------GAHSCDTLGMADVGTACDP------DRSCSIIEDDG-LQAAFTVAHELGHVFNMPHDDAKQCASVNG-----DQWGAHMMASTLSNLNQLDPWSPCSALMVTSFLDNGHGQCLLDKPQKP----EELPQTLPGSVYDADRQCRLTFGE--ESQHCPDLSSTCAALWCTVTSANGLLVCQTKNFPWADGTPCGSNSYCMAGQCLSKT--------------------------------------EAAKYETPVNGGWGSWGSWGDCSRTCGGGVQYSFR----------DCVNPRPKNGGKYCEGKRIQYRSCNTETCPDSNGLTFREEQCLAHNDLSSQVSLGSGEGVEWVPKYAGVSPKDRCKLVCRAKGTGYFFILKPKVADGTPCTPDSTSVCVQGQCVKAGCDRVIGSDKRFDKCGICGGDGSTCKKVSGSMERA--------RPGYQDVVTIPAGATHLDVKQRSFGGRSQDNSYLAVRRQDGSYLLN----------------GDYKLTTLETDISVKGALLRYSGS-------SVLLERLRSFAPLPEPLTIQVLSVGESPRPRVKYSYFAPRPNGSNRPSINAISKAVDAEWFLGEWGTCSKTCGGGIQTRDVMCLDSKRRPSK---NCVDELRPASSRQCALQDCPFWFLGEWGTCSKTCGGGIQTRDVMCLDHNRRPSKDCVELHPPSSRQCALQDCPAWFLGEWGTCSKTCGGGIQKRDVMCLDHNHRPSEDCVELRPASSRQCALQDCPFWLPGNWSECSRTCGRGFRKRTLSCITHDGHILPNSSCNATD--RPRPLLNLCNLTPC----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1Z6-1", "uniprot_id": "Q9W1Z6_DROME", "id": "Q9W1Z6-1", "name": "", "aln": "--MTVAAIGSNRHRRLALIVLTTLWLLIGASSSSSSTSSTNPKSVNIELRRKRSLHYNGIELDKNTLVGHLREHERALIFGSRSPEEAPEFKLVHLAQQRPEEQQRLEERKRPGEAEQHGGNPHQRRQRRSLPSEDGNGPLP---PEEEEQEAGEDVEARLQLQQSPQLIDDAFIFIRRTENGTQFVEHSPQLLKRLERCFYRSPAAALDLCEPGNVRGVFQQN--GSDLVIHPLPARFGTGTHVLYQARVDKSGGGYSEASSRRTASPLDSQLQFEPDAEEFN-------EPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQRRRRYIGDAPRSRWSDIPEELFIETAIFVDSDLYAHMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPP-GLVRSRDVENYLNSFCKWQEK-LNPFSDADPLHYDHALVLTGLDLVT--YDKGKANSQVVGMATVKGMCTS------IYSCTINEAKH-FESVFVVAHEIGHNLGMRHDAKEISCDP----------TMHIMSPKLG--SGKVTWSKCSRTYLEDFLMDPQAECLFDRDSFAGPWDHTAGGRLPGERFNANQQCMLRFGKNFMQASTQSKMEICRDLHCRQDGL------PWTSHPALEGTECGPNMWCRGGTCEARSSKQGSYSALKSWPPEHIPEATHEKIIRHEPNRIPPLLHDYNPMDNELPGSPSNWGEWSEPS-ACESGCLYGQSRRLLEGSTGLRTLNRSCLNFPSRCIGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQAR-KSDPELTGEGQQLPSTLDASCKIFCRTRTNGTKSRRWTFPDGTTCKAKQHNPEDITYCISGRCERFSCDNSTSNFFKMDSSFCEARSVRPTRDSSDQESRQ--------QTNRQRYAERQEGKPQKNHYENEVAKRPSYGQGNHINAPASPYKRRNYHKPYPPEIPRPPPPASASLIALDRSSSSESEWVAHPGCHSNCMTDSKGVQGVTSRLTGVESIQLCSYRIQPCERLQTAAEYAEQTCAR-YRQKVRGLS--GHGAQISASIDEPDRSCRVGCQDEFIKYRYYLVNGRNGHFPPGTRCSPVGKRYCVYGRCLEFGDDDLPLDKTHISLG--------------------------------------------------------------------------------------------------------QLRTRRKRSSISNDLFNITEIFIKPSHSDISAENIEFTQPIHVSADELSSKSR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7YZP6-1", "uniprot_id": "B7YZP6_DROME", "id": "B7YZP6-1", "name": "", "aln": "MSSPLVLFTALLLVSSTICQGLPDLHKQMTPEQLQSVFHVDTHDAVPHYELVQLQHHENNHNRRRRSIGKGPKVNAALPPHHVKKDLSKNAYYSELKHEALASGGNHLFAPEVSAIKSHNVSFSAFGQHLNLSLRATQGLFKGAPHQLRMWTVGSEPNATHGLDLQEIVHEQHTSNDVGEVFQD------------------EKNMAAILMRRHMETGDLIMEGSIGHDLVIKPLPHELSPNPEESHHIIYKREASAAEGQLSDFAFMEPDDLLASEKLERLQR--------RQRRSRRSAPSSPDFEDLNDEDEGALDGEPQVAESRTRSRRQ------APYIIYPEVLVIVDYDGYRLHGGD-----NLQVKRYFISFWNGVDLRYRLLKGP-RIRISIAGIIISRGRDATPYLERNRVGRDAIDSAAALTDMGKYLFRERRLPVYDIAVAITKLDMCRRTSAYGECNRGTAGFAYVGGACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDGSPPPSYLGGPGAQRCRWEDGYIMSDLRHTERGFRWSACTVQSFHHFLNGDTATCLHNAPHED----SALGRSLPGTLLSLDAQCRRDRGT----YACFKDERVCAQLFCFDAQT----GYCVAYRPAAEGSACGNGYHCLDGRCTPLPSN-----------------------------IIPDYGHNYRLVYNKIDNKKDAAEDVESSSEETESQEDETESVEDQDEGTTSSEEQEDNKIEQSSAAGGAAAQSTTTARSTTTTTVRTTSTTTTTAKPKSKSFGYLHRSLPERQWMQDNGVLVTTRISSSVSSSSSGSSSGEAAATSTRRPTTTTTTQTPNLFQIYTHELRKQIEYYLHMLQTQQHATKFQPEQQQQQSQQQQSIVEIPLVQKSLTNYSVTSSSSSTSNGAKQQPPSNKDENQRQQQQQQQAQQQLQDG----------LPDEENEATAGIQSNEAIERQKRKFPTTPTAATSAAQKSATPATPATSATSARPTPTTAKPITTSSFLDAYFKKLQALHDAGSASSSTTTTTTTSVSSSVSSATSSKQQHPQQQQQQQVQQIADGSHFLKRTPHRSSLKAYKTSSSSSNNSSSQTQQQQQQQQQQYATN----------------------------------------------------------------------------------------------------YIGDTTNNQPAVLDNSGSASSTTETAKKPKIKTQKLIRRTRVMQTQTQTI-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . .: :: * . . : .* . **: : . . : * .*:* . . . * . : * :..* . : ::::: . *: . : : : : : : . : . . . : ** *: :* *: * . . *:* * * * :: * :.. :..***:** :. ** . : . * . ** *: . ** . . ** : *** . : ** * . * * * * :*: ** . * * * . : . . . . . * . : . . * : . * . . . . .. . .. . .. : . :: . . . . :. . : . . . : ... . .. . . . . :: . : .. : : . . * . . . . . : * . . . : . : . .. : :. . . : ", "identical_positions": 60, "similar_positions": 162, "identity": "4.63%" }, { "cls_id": "homologset.agr.RGD:621242", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESP7-1", "uniprot_id": "ATS4_RAT", "id": "Q9ESP7-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRTKRFASLSR--------------------------------------------------FVETLVVADDKMAAFHGAGLKH--------YLLTVMAAAAKAFKHPSIRNPVNLVVTRLVILGSGQEVPQVG-PSAAQTLRSFCTWQKGLNPPNDSDPDHFDTAILFTRQDLC----GVSTCDALGMAGVGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFNMLHDNSKPCANLNGQGSSSRHVMAPVMAHVDPEEPWSPCSARFITDFLDNGYGHCLLDKPEAP----LHLPVTFPGKDYDADRQCQLTFGPDSSHCPQLPPPCAALWCFGHLNGHAMCQTKHSPWADGTPCGPAQACMGGRCLHVDQ-----------------------------------LKDFN------IPQAGGWGPWGPWGDCSRTCGGG---VQFSSRDCTKPVPR---NGGKYCEGRRTPFRSCNTKNCPHGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRYTGVAPRDQCKLTCQARALGYYYVLEPRVADGTPCSPDSSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCG----------------------------GNGSSCSKQSGSFKKFRYGYSDVVTIPAG---------------------RTHILVRQQGGSGLKSIYLALKLADGSYALNG-------------------EYTLMPSSTDVVLPGAVSLRYSGRTAASETLSGHGPLAQPLTLQVLVAGNP--QNVRLRYSFFVPRPVPSTPRP------------------------PPQNWLQRRAEILEILRKRTWAGRK---------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BNJ2-1", "uniprot_id": "ATS4_MOUSE", "id": "Q8BNJ2-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 4", "aln": "-------------------------------------------MSQMGLHPRRGLTGHWLQRFQPCLPLHTV-----QWRRLLLLAFLLSLAWPASPLPREEEIVFPEKLNGSSILPGSGVPARLLYR----LPAFGEMLLLELEQDPGVQVEG-----LTVQYLGQAPEMLGGAEPGTYLTGTINGDPESVASLHWDG----------GALLGVLQYRGAELHLQPLEGGALNSAGGPGAHILRRKSPASSQGPMCTVKAPSGSPSPISRRTKRFASLSR--------------------------------------------------FVETLVVADDKMAAFHGTGLKR--------YLLTVMAAAAKAFKHPSIRNPVNLVVTRLVILGSGQEGPQVG-PSAAQTLRSFCTWQRGLNTPNDSDPDHFDTAILFTRQDLC----GVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFNMLHDNSKPCTNLNGQGGSSRHVMAPVMAHVDPEEPWSPCSARFITDFLDNGYGHCLLDKPEAP----LHLPATFPGKDYDADRQCQLTFGPDSSHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTPCGSSQACMGGRCLHVDQ-----------------------------------LKDFN------VPQAGGWGPWGPWGDCSRTCGGG---VQFSSRDCTRPVPR---NGGKYCEGRRTRFRSCNTENCPHGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRYTGVAPRDQCKLTCQARALGYYYVLEPRVADGTPCSPDTSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCG----------------------------GDGSRCSKQSGSFKKFRYGYSDVVTIPAG---------------------ATHILVRQQGGSGLKSIYLALKLSDGSYALNG-------------------EYTLMPSPTDVVLPGAVSLRYSGATAASETLSGHGPLAQPLTLQVLVAGNP--QNARLRYSFFVPRPVPSTPRP------------------------PPQDWLQRRAEILKILRKRPWAGRK---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75173-1", "uniprot_id": "ATS4_HUMAN", "id": "O75173-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 4", "aln": "-------------------------------------------MSQTGSHPGRGLAGRWLWGAQPCLLLPIVPLSWLVWLLLLLLASLLPSARLASPLPREEEIVFPEKLNG-SVLPGSGAPARLLCR----LQAFGETLLLELEQDSGVQVEG-----LTVQYLGQAPELLGGAEPGTYLTGTINGDPESVASLHWDG----------GALLGVLQYRGAELHLQPLEGGTPNSAGGPGAHILRRKSPASGQGPMCNVKAPLGSPSPRPRRAKRFASLSR--------------------------------------------------FVETLVVADDKMAAFHGAGLKR--------YLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVG-PSAAQTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQDLC----GVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFNMLHDNSKPCISLNGPLSTSRHVMAPVMAHVDPEEPWSPCSARFITDFLDNGYGHCLLDKPEAP----LHLPVTFPGKDYDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTPCGPAQACMGGRCLHMDQ-----------------------------------LQDFN------IPQAGGWGPWGPWGDCSRTCGGG---VQFSSRDCTRPVPR---NGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRYTGVAPQDQCKLTCQAQALGYYYVLEPRVVDGTPCSPDSSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCG----------------------------GDGSGCSKQSGSFRKFRYGYNNVVTIPAG---------------------ATHILVRQQGNPGHRSIYLALKLPDGSYALNG-------------------EYTLMPSPTDVVLPGAVSLRYSGATAASETLSGHGPLAQPLTLQVLVAGNP--QDTRLRYSFFVPRPTPSTPRP------------------------TPQDWLHRRAQILEILRRRPWAGRK---------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1Z6-1", "uniprot_id": "Q9W1Z6_DROME", "id": "Q9W1Z6-1", "name": "", "aln": "MTVAAIGSNRHRRLALIVLTTLWLLIGASSSSSSTSSTNPKSVNIELRRKRSLHYNGIELDKNTLVGHLREHERALIFGSRSPEEAPEFKLVHLAQQRPEEQQRLEERKRPGEAEQHGGNPHQRRQRRSLPSEDGNGPLPPEEEEQEAGEDVEARLQLQQSPQLIDDAFIFIRRTENGTQFVEHSPQLLKRLERCFYRSPAAALDLCEPGNVRGVFQQNGSDLVIHPLPARFGTGTHVLYQARVDKSGGGYSEASSRRTASPLDSQLQFEPDAEEFNEPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQRRRRYIGDAPRSRWSDIPEELFIETAIFVDSDLYAHMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPPGLVRSRDVENYLNSFCKWQEKLNPFSDADPLHYDHALVLTGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEISCDP------TMHIMSPKLGSG--KVTWSKCSRTYLEDFLMDPQAECLFDRDSFAGPWDHTAGGRLPGERFNANQQCMLRFG---KNFMQASTQSKMEICRDLHCRQDGLPWTSHPALEGTECGPNMWCRGGTCEARSSKQGSYSALKSWPPEHIPEATHEKIIRHEPNRIPPLLHDYNPMDNELPGSPSNWGEWSEPSACESGCLYGQSRRLLEGSTGLRTLNRSCLNFPSRCIGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQARKSDPELTGEGQQLPSTLDASCKIFCRTRTNGTKSRRWTFPDGTTCKAKQHNPEDITYCISGRCERFSCDNSTSNFFKMDSSFCEARSVRPTRDSSDQESRQQTNRQRYAERQEGKPQKNHYENEVAKRPSYGQGNHINAPASPYKRRNYHKPYPPEIPRPPPPASASLIALDRSSSSESEWVAHPGCHSNCMTDSKGVQGVTSRLTGVESIQLCSYRIQPCERLQTAAEYAEQTCARYRQKVRGLSGHGAQISASIDEPDRSCRVGCQDEFIKYRYYLVNGRNGHFPPGTRCSPVGKRYCVYGRCLEFGDDDLPLDKTHISLGQLRTRRKRSSISNDLFNITEIFIKPSHSDISAENIEFTQPIHVSADELSSKSR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.* . * *:** :..*..: *. .: :**::: .. ::**:: . :.:*:.** * * : * .. : *.*** **. **. .*:** *:* *:::* ** * :..:.:*** * :* . **:* * . ::*.*..***:** :.* ** .: . . : *:*:* :. : .** ** :: *** : ..**:*: . . :**: ::*::** * ** : * .. . * . : . * :** **. * ** * .. *:*:* ....** *. . *. * * :.. :.: * * . * ** * :*** :* .. *:.: . : . .:.* : :* ..: : *: :. : . : . ... .*: : *:.*** : .**. .. *:*..: . *. . :. :: ** .: :. **. : *: : ... .* ::* ... :. .* : *. . . .. : . *****. .. : : . *: ::* ::: . . * * : : *. *:*. ... ", "identical_positions": 140, "similar_positions": 214, "identity": "12.21%" }, { "cls_id": "homologset.agr.RGD:621243", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28572-2", "uniprot_id": "SC6A9_RAT", "id": "P28572-2", "name": "Sodium- and chloride-dependent glycine transporter 1", "aln": "--------------MAVAHGPVATSSPEQ------------------------------------------------------NGAVPSEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLVFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTPDCAGVLDASNLTNGSRPTALSGNLSHLFNYTLQRTSPSEEYWRLYVLKLSDDIGDFGEVRLPLLGCLGVSWVVVFLCLIRGVKSS--GKVVYFTATFPYVVLTILFVRGVTLEGAFTGIMYYLTPKWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHG----PGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVSIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPTIIFFILIFTVIQYRPITYNHYQYPGWAVAIGFLMALSSVICIPLYALFQLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTTTPSPEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P28571-3", "uniprot_id": "SC6A9_MOUSE", "id": "P28571-3", "name": "Sodium- and chloride-dependent glycine transporter 1", "aln": "MIGGDTRAASAHPGMASAQGPVATPSPEQPFPG--------------TTSVSLARPVLRVWHGAHSSGLLPNLIAQHSPAMAQNGAVPSEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTPDCAGVLDASNLTNGSRPAALSGNLSHLFNYTLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWVVVFLCLIRGVKSS--GKVVYFTATFPYVVLTILFVRGVTLEGAFTGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHG----PGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVSIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILIFTVIQYRPITYNHYQYPGWAVAIGFLMALSSVICIPLYALFQLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTTTPSPEDGFEVQPLHPDKAQIPIVGSNGSSRFQDSRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48067-1", "uniprot_id": "SC6A9_HUMAN", "id": "P48067-1", "name": "Sodium- and chloride-dependent glycine transporter 1", "aln": "MSGGDTRAAIARPRMAAAHGPVAPSSPEQVTLLPVQRSFFLPPFSGATPSTSLAESVLKVWHGAYNSGLLPQLMAQHSLAMAQNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSS--GKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHG----PGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAPSPEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VLY3-1", "uniprot_id": "Q9VLY3_DROME", "id": "Q9VLY3-1", "name": "", "aln": "--------------------------------------------------------------------------------MVYETSYDTGHKPFSPDLNRGKWDKPTDFMFACFGLALKLD-VFVASFWMFFDMGILGILPYFVYMSIYLVPIMVIHSFMGQFSSSGFISAFRLSPFFKGMGYVSGFLTISMLIYYSIFAAVPLLFIINSFRPTLPWS-CEGLSSWHNGSATLSSSCNKTLILEDFSEYNRSHQLLHVPSVLYFQNHYDSMQQDAVPDWYKDY-ELSWHFVGLFAIIWVVIAFIFYKFSETAKFGKLIRYMVIVTLVLLLVCFVRFLFLPGALNGLHRYVTPKASDMAMGVVS--TFIMVLHAFGAGWGSVITLSSFNGFKTDIMSYSWIISFG-----QIFIYIMFGMVSFMLEHYFNELSDVDDNGHVLSHWLLYLSSASALSTMAWPNLWTFIYYSMLLIAALIVMTTQIFTVLQSLFDEF--EVLRVRKQEVTFGLIGGIALCSFYFCTNHGIIFFSALG-LDAIFSHSLLHLLLLLVVLWIYGRERFQRDIEFMLGQPFASWKVFILRFIAPIILVICLLAGIALS---ISEHSYSTTVVFVMSIVLVVLPILAIPGYGFYYLYQSTG-TFCERFKRTCRPT-DWYPVEMEHR-----QQYEEAVDNTEMTHQLFEVTEEVN---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . . :*.**:*.: :*:::..* *: *. *: .: : : * ::***: : : :*::.:. :***:*.* :..:*:**:***:** .:: : ***.:. .:.: :::.*: .***: *:. . : :..*.:* .. * ** : : . .:.* : :.* :: *: ::* :.: *:*: : : : ::: **:: : . .. *:* : *** : * **: *: *:**: ..: . * : :::::*..**.:**::*:* *:.: * ***: :::*.::.** :* ::* * *:* * ::: ..**: :. . **::::: **:: .* . : *:: ::.**. * : :* **:*: . * .: : :: ** :: :. * ** :: :: : :::***:..: :**::*** * . : : **::* *:.: *: : :* . ...:.:::.: .::.** *.:: * :: * *: :*:*.: :*: ** *. :*** : :: .: *. . :: ", "identical_positions": 134, "similar_positions": 246, "identity": "18.82%" }, { "cls_id": "homologset.agr.RGD:621244", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0CG50-1", "uniprot_id": "UBC_MOUSE", "id": "P0CG50-1", "name": "Polyubiquitin-C", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEPSVTTKKVKQ----------------------EDRRTFLTT-VSKKSPPCACSWV-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CG48-1", "uniprot_id": "UBC_HUMAN", "id": "P0CG48-1", "name": "Polyubiquitin-C", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGV-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CG69-1", "uniprot_id": "UBIQP_DROME", "id": "P0CG69-1", "name": "Polyubiquitin", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIQA-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q63429-1", "uniprot_id": "UBC_RAT", "id": "Q63429-1", "name": "Polyubiquitin-C", "aln": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSVNTKKVKQEDTRTFLTTVSRKSPSCACSWV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9W418-1", "uniprot_id": "Q9W418_DROME", "id": "Q9W418-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAI----------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CG63-1", "uniprot_id": "UBI4P_YEAST", "id": "P0CG63-1", "name": "Polyubiquitin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******************.****:***:******************************************************************.****:***:******************************************************************.****:***:******************************************************************.****:***:******************************************************************.****:***:************************************************ ", "identical_positions": 365, "similar_positions": 15, "identity": "45.06%" }, { "cls_id": "homologset.agr.RGD:621245", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54319-1", "uniprot_id": "PLAP_RAT", "id": "P54319-1", "name": "Phospholipase A-2-activating protein", "aln": "MASGAARYRLSCSLPGHELDVRGLVCCLYPPG---AFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGK-FGTLLSGSWDTTAKVWLN----DKCMMTLQGHTAAVWAVKILPE-QGLMLTGSADKTIKLWKA-GRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQI-TGECLGVYYGHTNYIYSISVFPNCRD--FVTTAEDRSLRIW---KHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTEADERTASAEEIKAFERELSQATIDSKT-GDLGDINAEQLPGREHLNEPGTREGQTRLIRDGE-RVEAYQWSVSDGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNVSDDPWLVAYNFLQKNDLNPMFLDQVAKFIIDNTKGQTLGLGNTS-FSDPFTGGGRYVPGTSGP-SNTVQTADPFTGAGRYMPGSAGMDTTMAGVDPFTGNSAYRSAASKTVNIYFPKKEALTFDQANPTQILGKLKELNGSAPEEKKLTEDDLVLLEKILSLICGNASEKP--TAQQLQVLWKAINWPEDIVFPALDILRLSIKHPSVNENFCNEKEGDQFSSHLINLLNPKGKPANQLLALRTFCNCFVSQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLTLNYSVCFHKDHN----IEGKAQCLS-VISTILEVVQDLEATFRLLVALGTLISDDSNAIQLAKSLGVDSQIKKYASVSEP------AKVSECCRLILNLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P27612-1", "uniprot_id": "PLAP_MOUSE", "id": "P27612-1", "name": "Phospholipase A-2-activating protein", "aln": "MASGASRYRLSCSLPGHELDVRGLVCCLYPPG---AFVSVSRDRTTRLWAPDSPNRGFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKDTVCSLSSGK-FGTLLSGSWDTTAKVWLN----DKCMMTLQGHTAAVWAVKILPE-QGLMLTGSADKTIKLWKA-GRCERTFLGHEDCVRGLAILSETEFLSCANDASIRRWQI-TGECLEVYFGHTNYIYSISVFPNSKD--FVTTAEDRSLRIW---KHGECAQTIRLPAQSIWCCCVLENGDIVVGASDGIIRVFTESEERTASAEEIKAFERELSQATIDSKT-GDLGDINAEQLPGREHLSEPGTREGQTRLIRDGE-RVEAYQWSVSDGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNVSDDPWLVAYNFLQKNDLNPMFLDQVAKFIIDNTKGQTLGLGNTS-FSDPFTGGGRYVPGTSGP-SNTVQTADPFTGAGRYMPGSAGMDTTMTGVDPFTGNSAYRSAASKTVNIYFPKKEALTFDQANPTQILGKLKELNGTAPEEKKLTEDDLVLLEKILSLICNNSSEKP--TAQQLQILWKAINWPEDIVFPALDILRLSIKHPNVNENFCNEK-GDQFSSHLINLLNPKGKPANQLLALRTFCNCFVSQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLTLNYSVCFHKDHN----IEGKAQCLS-VISTILEVVQDLEATFRLLVALGTLISDDSNAIQLAKSLGVDSQIKKYVSVSEP------AKVSECCRLVLHLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y263-1", "uniprot_id": "PLAP_HUMAN", "id": "Q9Y263-1", "name": "Phospholipase A-2-activating protein", "aln": "MTSGATRYRLSCSLRGHELDVRGLVCCAYPPG---AFVSVSRDRTTRLWAPDSPNRSFTEMHCMSGHSNFVSCVCIIPSSDIYPHGLIATGGNDHNICIFSLDSPMPLYILKGHKNTVCSLSSGK-FGTLLSGSWDTTAKVWLN----DKCMMTLQGHTAAVWAVKILPE-QGLMLTGSADKTVKLWKA-GRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQI-TGECLEVYYGHTNYIYSISVFPNCRD--FVTTAEDRSLRIW---KHGECAQTIRLPAQSIWCCCVLDNGDIVVGASDGIIRVFTESEDRTASAEEIKAFEKELSHATIDSKT-GDLGDINAEQLPGREHLNEPGTREGQTRLIRDGE-KVEAYQWSVSEGRWIKIGDVVGSSGANQQTSGKVLYEGKEFDYVFSIDVNEGGPSYKLPYNTSDDPWLTAYNFLQKNDLNPMFLDQVAKFIIDNTKGQMLGLGNPS-FSDPFTGGGRYVPGSSGS-SNTLPTADPFTGAGRYVPGSASMGTTMAGVDPFTGNSAYRSAASKTMNIYFPKKEAVTFDQANPTQILGKLKELNGTAPEEKKLTEDDLILLEKILSLICNSSSEKP--TVQQLQILWKAINCPEDIVFPALDILRLSIKHPSVNENFCNEKEGAQFSSHLINLLNPKGKPANQLLALRTFCNCFVGQAGQKLMMSQRESLMSHAIELKSGSNKNIHIALATLALNYSVCFHKDHN----IEGKAQCLS-LISTILEVVQDLEATFRLLVALGTLISDDSNAVQLAKSLGVDSQIKKYSSVSEP------AKVSECCRFILNLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPY2-1", "uniprot_id": "Q9VPY2_DROME", "id": "Q9VPY2-1", "name": "", "aln": "MEPSLDNYKLSCELLGHSMDVRAVAVGPPTPEGRQTILSGSRDKSTKVWKPHG--NEYLESLTLQDHKNFISYICFLES-----ERWICTASNDATICIYKQDGFVPLLTLKGHESTVCALSAGLEPRSLISGSWDKTARVWTISEAGDVSFVALEGHEAAVWAVATLKE-QRKYVTGGADRNIYYWNAKGEKLRLLKGHTDCVRGVMGLDANTLLSCGNDAVLRFWNE-DGECVREMNGHSNYIYSMARNEALGDQVVVSCGEDSTLRMWNVITGDELGAPIIHPGISVWSVTCLQNGDIVTGCSDGVVRVFSHVPARQASEAVLKAFD--LVVATRKSQINEEIGGVKKTDLPGPEALLSNGTREGQTKMVRHADGSVKCYTWTLGN--WNLVGDVTGATGGTQSNSGKKLHEGKEYDFVFSVDISDTEPPIKLPYNRSDDPWQAAQTFIHRHSLPQAYLDQVANFIIKNSEGPVLMEQAPTGYQDPFTGGSRYVPGSSNTNMGSGGNVDPFTGASSYSTASS------------NAQSQVDVNFVRSGDKHFPVSNYRIFDTCDAKKVLEKMIEFNG------KLSLPDGRVGEEVLLAVIKLADQSPELDLTSLEALAILLKWPASMQFPVLDILRLAVRNEAIFSVLNNSH---NFLATVIPQLS--GSAPNQLMVVRCLANIMSHAAGRQNVMSRLAEIIDLVGAIKTGS-ANLQIAVATFYLNLTISQTLDVA----KSEVCHVVTSGIVELLKWAKDLEACYRSMQAIGNLTTTSCGQETIAQVVSVDYVMDKLRELTITPQDKNFSKVNSVGQALLAVF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36037-1", "uniprot_id": "DOA1_YEAST", "id": "P36037-1", "name": "Protein DOA1", "aln": "-----MGYQLSATLKGHDQDVRDVVAVDDSKV-----ASVSRDGTVRLWSKDD---QWLGTVVYTGQG-FLNSVCYDSEKELLLFGGKDTMIN--GVPLFATSGEDPLYTLIGHQGNVCSLSFQD--GVVISGSWDKTAKVWKE----GSLVYNLQAHNASVWDAKVVSFSENKFLTASADKTIKLWQNDKVIKTFSGIHNDVVRHLAVVDDGHFISCSNDGLIKLVDMHTGDVLRTYEGHESFVYCIKLLP-NGD--IVSCGEDRTVRIWSK-ENGSLKQVITLPAISIWSVDCMSNGDIIVGSSDNLVRIFSQEKSRWASEDEINELSTQVEKSTISSKT----IEFDESKLSPYEILQSPGRKEGQIVVVKSPQGTIEAHQFSNSS--WKKVGDVVG--AGATGNDKKIEFEGKTYDYVFDVDIEDGKPPLKLPINVSDNPYTAADNFLARYELPMSYRDQVVQFILKNTNGISLDQPNDN------------------------------------------------------ASSSAVSPSKTSVMKVLPVKQYLIMENYNPDTIFNGIVKINS-----------NEKTFDDEILAQIGGALHDIDESWELLLSFANTIRSNWEIKTPAYDIVRLIVKKLPYSSDIKDYIEEGLGNKNITLTMLTVRILVNCFNNENWGVKLLESNQVYKSIFETIDTEFSQASAK---QSQNLAIAVSTLIFNYSALVTKGNSDLELLPIVADAINTKYGPLEEYQECEEAAYRLTVAYGNLATVEPTLRQFANSVTWLANIKRSYGNVPR--------FKDIFDDLS---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**. * **. *** :. . * *** :.::* .. : .: *:. :* . * * : :: .. ** * **:..**:** ::*****.**:** . . *:.* *:** . : : :*..**:.: *: * * ** : :. ::**.**. :: : *: : ** .::*.: * .*: .** ::*:* .. * *. *:*. :.****:.*.**.::*:*:. * ** :: :. : :* .*: .. .*. * * . * :*** ::: : ::.: :: .. * :***.* .. .. * .*** :*:**.:*:.: *. *** * **:*: .* .*: : .* : ***.:**:.*::* * . ..* : :* .: :: :. :: : ::*. : :. : : .. * : :. .: *. **:** ::: . : : : : * : . : : : ::. :. . . *: **::*: :* : . .. :. : : : ** :* * *.* : . :*: : :.: ... : ", "identical_positions": 142, "similar_positions": 220, "identity": "17.15%" }, { "cls_id": "homologset.agr.RGD:621246", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04750-1", "uniprot_id": "TOP1_MOUSE", "id": "Q04750-1", "name": "DNA topoisomerase 1", "aln": "MS------------------------------GDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHK---------EHK------------------KDKDKDREKSKHSN----------------SEHKDS---------EKKHKEKEKTKHKDGSSEKHKDKHKDRDKERRKE-EKIRAAGDAKIKKEKENGFSSPPRIKDEPEDDGYFAP------------------------------------------------------------------------------------------------------------------PKEDIKPLKRLRDEDDADYKP-----------------KKIKTEDIKKE-----KKRKSEEE----EDGKLKKPKNKDKDKKVAEPDNK-KKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPESVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNT----ITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMEN-KQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDA-------------------------------------------------------------------KKDQLADARRDLKSAKADAKVMKDAKTKKV-----------VESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WUL0-1", "uniprot_id": "TOP1_RAT", "id": "Q9WUL0-1", "name": "DNA topoisomerase 1", "aln": "MS------------------------------GDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHK---------EHK------------------KDKDKDREKSKHSN----------------SEHKDS---------EKKHKEKEKTKHKDGSSDKHKDKHKDRDKEKRKE-EKIRAAGDAKIKKEKENGFSSPPRIKDEPEDDGYFAP------------------------------------------------------------------------------------------------------------------PKEDIKPLKRPRDEDDADYKP-----------------KKIKTEDIKKE-----KKRKLEEE----EDGKLKKPKNKDKDKKVAEPDNK-KKKAKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNT----ITNLSKCDFTQMSQYFKAQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMEN-KQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDA-------------------------------------------------------------------KKDQLADARKDLKSAKADAKVMKDAKTKKV-----------VESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11387-1", "uniprot_id": "TOP1_HUMAN", "id": "P11387-1", "name": "DNA topoisomerase 1", "aln": "MS------------------------------GDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHK---------EHK------------------KEK--DREKSKHSN----------------SEHKDS---------EKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKE-EKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVP------------------------------------------------------------------------------------------------------------------PKEDIKPLKRPRDEDDADYKP-----------------KKIKTEDTKKE-----KKRKLEEE----EDGKLKKPKNKDKDKKVPEPDNK-KKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNI----ITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMEN-KQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDA-------------------------------------------------------------------KKEQLADARRDLKSAKADAKVMKDAKTKKV-----------VESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RL46-1", "uniprot_id": "A0A8M1RL46_DANRE", "id": "A0A8M1RL46-1", "name": "DNA topoisomerase I", "aln": "MS------------------------------GDHPHKHRQVESGSVEYNSHKHKDKHKDRQHGHK---------EQK------------------RDK--ERENSKNGH----------------SEHKSSS--------ERKHREKEKDRLK--------------HKEKRKE-EKFHGS-DGKYR-DKENGFVSPSSIKVEEDTDNHHTV------------------------------------------------------------------------------------------------------------------KHE--KPLKRERDEDEYEHKP-----------------KKVKVENEKKV-----KKRKQEEEDSDFEERVEKKPKKKIKEEKK-DTTGG-KKKAKNQPEEKWKWWEEERYTDGSKWRFLEHKGPVFPPPYEPLPGHIKFYYDGNAMKLSPAAEEVATFYAKMLEHEYTTNEIFRKNFFKDWRKEMTSEEKSK----ITELKKCDFTQMHEYFKAQSEARKQMSKEEKQKNKEENERILQEYGFCLMDNHRERIGNFRIEPPGLFRGRGDHPKMGKLKRRIRPEDIIINCSKDSVQPKAPPGTRWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVERIRAQYREDWRSKEMRIRQRAVALYFIDKLALRAGNEKDEGETADTVGCCSLRVEHIKLHPQLDGQDYVVEFDFLGKDSIRYYNKIPVEKRVFKNLQLFLEN-KQSEDDLFDRLNTSILNKYLQELMDGLTAKVFRTYNASITLQQQLKELTSPGENIPEKILSYNRANRAVALLCNHQRAPPKTFEKSMQNLQTKIDE-------------------------------------------------------------------KKKQLSAAKKEHKAAKADAKALHDEKSKKA-----------VETKKKAVQRISEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVSWCKKWGVPIEKIYSKTQRDKFAWAIDMADEDFEF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P30189-1", "uniprot_id": "TOP1_DROME", "id": "P30189-1", "name": "DNA topoisomerase 1", "aln": "MSGDVAAENSIHIQNGGSCEVVQSNGVTTNGHGHHHHHHHSSSSSSSSKHKSSSKDKHRDREREHKSSNSSSSSKEHKSSSRDKDRHKSSSSSSKHRDKDKERDGSSNSHRSGSSSSHKDKDGSSSSKHKSSSGHHKRSSKDKERRDKDKDRGSSSSS-RHKSSSSSRDKERSSSSHKSSSSSSSSKSKHSSSRHSSSSSSKDQPSYDGVFVKPEPVSQQLMHSGSVDAFQMQQLGSYEAAAAGTNFNGNGNVAGANYKNGYEESIVDIKKEEESFNNLSQASSCDYSMSQFRADEPPFVVKHEQSYAEEDSTMNYNDHDDDADEMNDDEEDVPLAMRKRKQEATDRPDGGMDNDDDDDIPLLARKKVKKEKIKKESKEKSKKRVKEEPSDDYGNVKPKKKKMKKEPEPAVSPGKRQKAKAKVEEEEVWRWWEEEKRADGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREI----IKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDE-DQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEH-KKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKA-------------------------------------------------------------------KREAIEKCESEYHS--------RDEK------------------KGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04786-1", "uniprot_id": "TOP1_YEAST", "id": "P04786-1", "name": "DNA topoisomerase 1", "aln": "--------------------------------------MTIADASKVNHELSSDDDDDVPLSQTLK------------------------------KRKVASMNSASLQD----------------------------------------------------------EAEPYDSDEAISKISKKKTKKIKTEPVQSSS---------------------------------------------------------------------------------------------------------------------------------------LPSPPAKKSATSKP-----------------KKIKKEDGDVK----VKTTKKEEQ----ENEKKKREEEEEE-----------DKKAK-EEEEEYKWWEKENEDDTIKWVTLKHNGVIFPPPYQPLPSHIKLYYDGKPVDLPPQAEEVAGFFAALLESDHAKNPVFQKNFFNDFLQVLKESGGPLNGIEIKEFSRCDFTKMFDYFQLQKEQKKQLTSQEKKQIRLEREKFEEDYKFCELDGRREQVGNFKVEPPDLFRGRGAHPKTGKLKRRVNPEDIVLNLSKDAPVPPAPEGHKWGEIRHDNTVQWLAMWRENIFNSFKYVRLAANSSLKGQSDYKKFEKARQLKSYIDAIRRDYTRNLKSKVMLERQKAVAIYLIDVFALRAGGEKSE-DEADTVGCCSLRYEHVTLKPPN-----TVIFDFLGKDSIRFYQEVEVDKQVFKNLTIFKRPPKQPGHQLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNKG-SVAEKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANNRIQELEWQKIRCKRAILQLDKDLLKKEPKYFEEIDDLTKEDEATIHKRIIDREIEKYQRKFVRENDKRKFEKEELLPESQLKEWLEKVDEKKQEFEKELKTGEVELKSSWNSVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEKIFTKTLREKFKWAIESVDENWRF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. . . .*.. .: * : * . : :. . . * .. . . . . . *.. * :.. :* **:* *. . *. ** : *: : : : . *.* : *: ::***:*. : ** *:*:* :*.* *: :* :::****: :.*. :**.* *:* :*: :: .: :*.:***:*: : :. *.:: :*:* :* :**: :.* :* :.:** : *.* : ::: ** :*.::*::.**::***.****** *** * :***: ..*: :* .**: * .* * :* *:****.* **. * **: ...**: * ..* :**:.* *:*.**:*.. :: ** * : :** * **:***:*:** :*****.**.* : ********** **: *: .* *** ******:*::: *:*:***** :* . *: .:*****:. :**::*:: * ************* *:*.**. :. . .:. *:* ** ***:**:******: .* . ::: : : :*. *.. : .. . . * :::: ::: . .:* .*::**. ::*****:**:***::* :*** .******:.** * ** **:. .**::.*", "identical_positions": 246, "similar_positions": 227, "identity": "22.91%" }, { "cls_id": "homologset.agr.RGD:621247", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NHW5-1", "uniprot_id": "RLA0L_HUMAN", "id": "Q8NHW5-1", "name": "Putative ribosomal protein uL10-like", "aln": "MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKVVVLMGKNTMMRKAIRGHLENNPALEKLLPHIWGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNML---NISPFSFGLVIQQVFDNGSIYNPEVLDKTEETLHSRFLEGVRNVASVCLQTGYPTVASVPHSIINGYKRVLALSVETDYTFPLAENVKAFLADPSAFVAAAPVAADTTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P05388-1", "uniprot_id": "RLA0_HUMAN", "id": "P05388-1", "name": "Large ribosomal subunit protein uL10", "aln": "MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNML---NISPFSFGLVIQQVFDNGSIYNPEVLDITEETLHSRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFVAAAPVAAATTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19945-1", "uniprot_id": "RLA0_RAT", "id": "P19945-1", "name": "Large ribosomal subunit protein uL10", "aln": "MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNML---NISPFSFGLIIQQVFDNGSIYSPEVLDITEQALHTRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFAAAAPVAAATTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14869-1", "uniprot_id": "RLA0_MOUSE", "id": "P14869-1", "name": "Large ribosomal subunit protein uL10", "aln": "MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNML---NISPFSFGLIIQQVFDNGSIYNPEVLDITEQALHSRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETEYTFPLTEKVKAFLADPSAFAAAAPAAAATTAAPAAAAAPAKAEAKEESEESDEDMGFGLFD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9PV90-1", "uniprot_id": "RLA0_DANRE", "id": "Q9PV90-1", "name": "Large ribosomal subunit protein uL10", "aln": "MPREDRATWKSNYFLKIIQLLDDFPKCFIVGADNVGSKQMQTIRLSLRGKAVVLMGKNTMMRKAIRGHLENNPALERLLPHIRGNVGFVFTKEDLTEVRDLLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKPGDKVGASEATLLNMLNMLNISPFSYGLIIQQVYDNGSVYSPEVLDITEDALHKRFLKGVRNIASVCLQIGYPTLASIPHTIINGYKRVLAVTVETDYTFPLAEKVKAYLADPTAFAVAAPVAAATEQKSAAPAAKEEAP-KEDSEESDEDMGFGLFD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P19889-1", "uniprot_id": "RLA0_DROME", "id": "P19889-1", "name": "Large ribosomal subunit protein uL10", "aln": "MVRENKAAWKAQYFIKVVELFDEFPKCFIVGADNVGSKQMQNIRTSLRGLAVVLMGKNTMMRKAIRGHLENNPQLEKLLPHIKGNVGFVFTKGDLAEVRDKLLESKVRAPARPGAIAPLHVIIPAQNTGLGPEKTSFFQALSIPTKISKGTIEIINDVPILKPGDKVGASEATLLNML---NISPFSYGLIVNQVYDSGSIFSPEILDIKPEDLRAKFQQGVANLAAVCLSVGYPTIASAPHSIANGFKNLLAIAATTEVEFKEATTIKEYIKDPSKFAAAASASAAPAAGGATEKKEEAKKPESESEEEDDDMGFGLFD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P05317-1", "uniprot_id": "RLA0_YEAST", "id": "P05317-1", "name": "Large ribosomal subunit protein uL10", "aln": "--MGGIREKKAEYFAKLREYLEEYKSLFVVGVDNVSSQQMHEVRKELRGRAVVLMGKNTMVRRAIRGFLSDLPDFEKLLPFVKGNVGFVFTNEPLTEIKNVIVSNRVAAPARAGAVAPEDIWVRAVNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVDAGNKVGQSEASLLNLL---NISPFTFGLTVVQVYDNGQVFPSSILDITDEELVSHFVSAVSTIASISLAIGYPTLPSVGHTLINNYKDLLAVAIAASYHYPEIEDLVDRIENPEKYAAAAPAATSAASGDAAPAEEAAAE---EEEESDDDMGFGLFD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *::** *: : :::: . *:**.***.*:**: :* .*** .*********:*:****.*.: * :*:***.: ********: *:*::: :: .:* *.**.**:** .: : * ***: * ********.:.***::*****:.** ::..*:*** ***:***:* *****::** : **:*.*.:: ..:** . : * :* ..* .:*::.* ****:.* *:: *.:* :**:: :. : : : :* :..**..:: . *: :.**.*:********", "identical_positions": 132, "similar_positions": 106, "identity": "41.25%" }, { "cls_id": "homologset.agr.RGD:621248", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SWU9-1", "uniprot_id": "ACACA_MOUSE", "id": "Q5SWU9-1", "name": "Acetyl-CoA carboxylase 1", "aln": "-------------------------------------MDEPSPLAKTLELN--QHSRFIIGSVSEDNSEDE-----------------------------ISNLVKLDLEE-----KEGSLSPAS------VSSDTLSDLGISGLQDGLAFHMRSSMSGLHLVKQGRD--------------------------------------------------RKKID--------------SQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNG--IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQDLYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQ-DGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLFRIKDIRMMYGVSPWGDAPIDFENS-------AHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQAE-RPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGIKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPLNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNG--HYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQ---LCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIEN--------LQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNR-----GNIPTLNRMSFASNLNHYGMTHVASVSDVLLDNAFTP--PCQRMGGMVSFRTFEDFVRIFDEIMGCFCDSPPQSPTFPESGHTSLYDED--KVPRDEPIHILNVAIKTDGDIEDDRLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN-TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTTTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMSLKSPEYPDGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVS---ALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEVITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPT-KAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFN-REGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIRLAERLGTPELS--PTERKELESKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11497-1", "uniprot_id": "ACACA_RAT", "id": "P11497-1", "name": "Acetyl-CoA carboxylase 1", "aln": "-------------------------------------MDEPSPLAKTLELN--QHSRFIIGSVSEDNSEDE-----------------------------ISNLVKLDLEE-----KEGSLSPAS------VSSDTLSDLGISALQDGLAFHMRSSMSGLHLVKQGRD--------------------------------------------------RKKID--------------SQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGANNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNG--IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQDLYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQ-DGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLFRIKDIRMMYGVSPWGDAPIDFENS-------AHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQAE-RPDTMLGVVCGALHVADVNLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGIKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPLNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNG--HYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQ---LCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYDVRHNQVESIFLSAIDMYGHQFCIEN--------LQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNR-----GNIPTLNRMSFASNLNHYGMTHVASVSDVLLDNAFTP--PCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPESGHTSLYDED--KVPRDEPIHILNVAIKTDGDIEDDRLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN-TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTTTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMSLKSPEYPDGRDVIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDSEDPYKGYKYLYLTPQDYKRVS---ALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKNVHSSVPLLNSKDPIDRIIEFVPT-KAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSVPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFN-REGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIRLAERLGTPELS--PTERKELESKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHSANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q13085-1", "uniprot_id": "ACACA_HUMAN", "id": "Q13085-1", "name": "Acetyl-CoA carboxylase 1", "aln": "-------------------------------------MDEPSPLAQPLELN--QHSRFIIGSVSEDNSEDE-----------------------------ISNLVKLDLLEE----KEGSLSPAS------VGSDTLSDLGISSLQDGLALHIRSSMSGLHLVKQGRD--------------------------------------------------RKKID--------------SQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNG--IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQ-DGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDSPIDFEDS-------AHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLDRLIAEKVQAE-RPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVLAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNG--HYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQ---LCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIEN--------LQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNR-----GNIPTLNRMSFSSNLNHYGMTHVASVSDVLLDNSFTP--PCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSPPQSPTFPEAGHTSLYDED--KVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVDHGIRRLTFLVAQKDFRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN-TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWVDPEDPYKGYRYLYLTPQDYKRVS---ALNSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGMIAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPT-KTPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFN-REGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVVIDSSINPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELS--TAERKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVISDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLTEEDGVHSVIEENIKCISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVIRILSTMDSPST-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YZ52-1", "uniprot_id": "A0A8M6YZ52_DANRE", "id": "A0A8M6YZ52-1", "name": "acetyl-CoA carboxylase", "aln": "-------------------------------------MAEQDSTEKKLPAVAALHSHFIVGSVSEENSEDE-----------------------------TAGKLDLQLED-----NPRSLSPSS------VSSDSTYEMGFDSLDG-PLHNMRPSMSGLHLVKQGRD--------------------------------------------------RRRID--------------LQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGTNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLHKNG--IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGTGLTVEWTENDQKKGIINVPTELYEQGCVHDVEAGLKAAEQVGFPVMVKASEGGGGKGIRKVNCAEDFPNLYRQVQAEVPGSPIFVMQLAKHARHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATSDVFEDMEKCAVKLAKMVGYVSAGTVEYLYSQ-DSSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLHRIKDIRVLYGMQPWGDSPIDFDGL-------STTPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQHNSIDTGWLDRLISEKMQAE-RPDTMLGVVSGALHVADVNFRNSVSNFLHSLERGQVLPAHTLLNTVDVELIYEGTKYVLKVTRQSPNSYVVIMNCSSVEVDVHRLSDGGMLLSYDGSSYTTYMKEEVDRYRIIIGNKTCVFEKENDPSVLRSPSAGKLIQYTVEDGGHVFAGQCYAEIEVMKMVMTLTASESGCIHYVKRAGAVLEPGCIIGKLQLDDPSRVQQAELYTGTLPSIQSVALRGEKLHRVFHSTLGHLVHIMNGYCLPEPFFSAKLKEWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPAVEKAIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQKYRSGIRGHMKAVVMDLLRQYLRVEVQFQHG--HYDKCVFALREENKVDMANVLNYIFSHAQVTKKNCLVTMLIDQ---LCGRDPTLTDELMAILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIEN--------LQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCIVEFQFMLPTSHPNR-----GNIPTLNRMSFSSNLNHYGMVHVASVSDVLLDTSFTP--PCQRMGAMVSFRSFQEFTRNIKDVLSCFSDSPPSTPTFPEGGNPVLYREEDSKSIQDEPIHILNVAIKTDSDIDDDGLAAMFREFTQSKKSLLFDHGIRRLTFLVAQKDFRKQINCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFALTAIPCANHKMHLYLGAARVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLHNEAERLLLEAMDELEVAFNN-TTVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKQIPIRLFLTNESGYYLDISLYKEVTDSRTGQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYVYDFPEMFRQALRKLWQSMDAHANLPKCPLPSELLTFTELVLDSQGQLVQMNRLPGGNEIGMVAWRMTLRTPEYPAGREIIVISNDITHKIGSFGPQEDVLFQQASEMARESGIPRIYIAANSGARIGLAEEIRHMFHVAWQDPVDPYKGFKYLYLTPQDYKKVS---ALNSVHCEHVEDEGESRYKITDIIGKEEGLGVENLRGSGMIAGESSLAYEDIITMNLVTCRAIGIGAYLVRLGQRTIQVENSHIILTGAGALNKVLGREVYTSNNQLGGVQIMHNNGVTHTNVCDDFEGVYTLLHWLSYMPKNMSSPVPILSAKDPIDRAIEFVPT-KAPYDPRWMLAGRPNQNIKGAWVSGFFDQGSFLEIMQPWAQSVVVGRARLGGIPTGVVAVETRSVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTAQAIKDFN-REGLPLIVFANWRGFSGGMKDMYDQVLKFGAYIVDGLREYRQPVLVYIPPQAELRGGSWVVIDPTINPRHMEMYADKDSRGGVLEPEGTVEIKFRKKDLVKTMRRVDPVYMGLAERLGTPELS--VSERKELESKLKEREEFLLPIYHQVAVQFADLHDTPGRMQEKGVITDILEWSTSRQFFYWRLRRLLLEETVKRKIQCANSELTDGQVQAMLRRWFVEAEGAVKAYLWDSNEDVVEWLERQLAEEEGARSVIDENIKYIRRDHILKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDTPASS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z784-1", "uniprot_id": "A1Z784_DROME", "id": "A1Z784-1", "name": "", "aln": "MLITILGTLAAFLAFLLTLIFGRGQKRSKPVQSSAATSATTATTGDSDNGNTNHNSSVIAATATATTTSSKPPIAPAAPPSAVKASDKRFPKACIKKVQFSSESLRSDVDELCDQLKDSALSNLSNDNIRIACHQNNNNSSINKNQNNNSIDISISISKMSETNESNDTAAQSAEGERPSFLVGDEIDERAAEAGEACDEFPLKMQNDVRQNGDISERRKRLRPSMSRGTGLGQDRHQDRDFHIATTEEFVKRFGGTRVINKVLIANNGIAAVKCMRSIRRWAYEMFKNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGSNNNNYANVELIVDIALRTQVQAVWAGWGHASENPKLPELLHKEG--LVFLGPPERAMWALGDKVASSIVAQTAEIPTLPWSGSDLKAQYSGKK-----IKISSELFARGCVTNVEQGLAAVNKIGFPVMIKASEGGGGKGIRRVDTTEEFPGLFRQVQAEVPGSPIFVMKLARGARHLEVQLLADQYGNAISLFGRDCSIQRRHQKIIEEAPAIVAQPEVFEDMEKAAVRLAKMVGYVSAGTVEYLYDP-EGRYFFLELNPRLQVEHPCTEMVADVNLPAAQLQIGMGIPLYRLKDIRLLYGESPWGSSVIDFENP-------PNKPRPSGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAASGGLHEFADSQFGHCFSWGENRQQARENLVIALKELSIRGDFRTTVEYLITLLETNRFLDNSIDTAWLDALIAERVQSE-KPDILLGVMCGSLHIADRQITESFSSFQTSLEKGQIQAANTLTNVVDVELINDGIRYKVQAAKSGANSYFLLMNSSFKEIEVHRLSDGGLLISLEGASYTTYMKEEVDRYRIVIGNQTCVFEKENDPSLLRSPSAGKLINMIVEDGAHVSKGQAYAEIEVMKMVMTLTSQEAGTVTFVRRPGAVLDAGSLLGHLELDDPSLVTKAQPFKGQFLQPENAPVP-EKLNRVHNTYKSILENTLAGYCLPEPFNAQRLRDIIEKFMQSLRDPSLPLLELQEVIASISGRIPISVEKKIRKLMTLYERNITSVLAQFPSQQIASVIDSHAATLQKRADRDVFFLTTQSIVQLVQRYRNGIRGRMKAAVHELLRQYYDVESQFQYG--HYDKCVGLVREHNKDDMQTVVNTIFSHSQVAKKNLLVTLLIDH---LWANEPGLTDELANTLSELTSLNRAEHSRVALRSRQVLIAAHQPAYELRHNQMESIFLSAVDMYGHDFHPEN--------LQRLILSETSIFDILHDFFYHSNRAVCNAALEVYVRRAYTSYELTCLQHLELSGGLPLVHFQFLLPTAHPNRLFSRMSSPDGLDQAAAESLGNSFVRTGAIAAFDSFEHFEMYSDEILDLLEDFVSPAMVNAKVLEAVEAADSISDSRHSTSINVSLSDPVTRANAAEEAKSTEPIHIVSVAVRETGELDDLQMAQIFGNYCQEHNEELFQRRIRRITFAALKK---------------RQFPKFFTFRARDKFTEDRIYRHLEPASAFHLELNRMKTYDLEALPTANQKMHLYLGKAKVSKGQEVTDYRFFIRSIIRHSDLITKEASFEYLQNEGERVLLEAMDELEVAFSHPHAKRTDCNHIFLNFVPTVIMDPAKIEESVTKMIMRYGPRLWKLRVLQAELKMVIRQSPQSPTQAVRLCIANDSGYFLDISMYTEQTEPETGIIKFKAYGEKQGSLHGHPISTPYMTKDFLQQKRFQAQSNGTTYVYDVPDMFRQMTERHWREFSKARPTVDIRTPDKILIECKELVLEGDNLVEMQRLPGENNCGMVAWRIVLATPEYPNGREIIVIANDLTYLIGSFGIKEDVLFAKASQLARQLKVPRIYISVNSGARIGLAEEVKAMFKIAWEDPEEPDKGFKYLYLSTEDYAQVA---NLNSVRAILIEDEGEQRYKITDIIGKDDGLGVENLRYAGLIAGETSQAYEEIVTIAMVTCRTIGIGSYVVRLGQRVIQIDNSHIILTGYAALNKLLGRKVYASNNQLGGTQIMFNNGVTHKTEAIDLDGVYTILDWLSYIPAYIGCDLPIVLPNDRIERPVDFMPT-KSPYDPRWMLGGRVNPVNANDWENGFFDRDSWSEIMASWAKTVVTGRARLGGVPVGVIAVETRTVEVEMPADPANLDSEAKTLQQAGQVWYPDSSYKTAQAIKDFG-REELPLIVFANWRGFSGGMKDMYEQIVKFGAYIVDGLREYKKPVLIYLPPNAELRGGAWAVLDSLINPRYMETYADPEARGGVLEPEGIVEIKYKEKDLVKTIHRLDPTTIALKKELDEANASGDKVRAAQVDEKIKARIAVLMHVYHTVAVHFADLHDTPERMLEKECISEIVPWRDSRRWLYWRLRRLLLEDAYIKKILRAQDNLSVGQAKQMLRRWLVEEKGATEAYLWDKNEEMVSWYEEQIN----AESIVSRNVNSVRRDAIISTISKMLEDCPDVALDAVVGLCQGLTPVNRGVVVRTLAQMQLNEETSNSNQG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00955-1", "uniprot_id": "ACAC_YEAST", "id": "Q00955-1", "name": "Acetyl-CoA carboxylase", "aln": "--------------------------------------------------------------MSEESLFES-----------------------------SPQKMEY-----------------------------EITNYSER-----HTELPGHFIGLNTVDKLEE----------------------------------------------------------------------------SPLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTG--LVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLITHKMTAE-KPDPTLAVICGAATKAFLASEEARHKYIESLQKGQVLSKDLLQTMFPVDFIHEGKRYKFTVAKSGNDRYTLFINGSKCDIILRQLSDGGLLIAIGGKSHTIYWKEEVAATRLSVDSMTTLLEVENDPTQLRTPSPGKLVKFLVENGEHIIKGQPYAEIEVMKMQMPLVSQENGIVQLLKQPGSTIVAGDIMAIMTLDDPSKVKHALPFEGMLPDFGSPVIEGTKPAYKFKSLVSTLENILKGYDN-----QVIMNASLQQLIEVLRNPKLPYSEWKLHISALHSRLPAKLDEQMEELVARSLRRGA----VFPARQLSKLIDMAVKNPEY-NPDKLLGAVVEPLADIAHKYSNGLEAHEHSIFVHFLEEYYEVEKLFNGPNVREENIILKLRDENPKDLDKVALTVLSHSKVSAKNNLILAILKHYQPLCKLSSKVSAIFSTPLQHIVELESKATAKVALQAREILIQGALPSVKERTEQIEHILKSSVVKVAYGSSNPKRSEPDLNILKDLIDSNYVVFDVLLQFLTHQDPVVTAAAAQVYIRRAYRAYTIGDIRVHEGVT-VPIVEWKFQLPSAAFST------------FPTVKSKMGMNRAVSVSDLSYVANSQSSPL-----REGILMAVDHLDDVDEILSQSLEVIPRHQSSS--------NGPAPDRSGSSASLSNVANVCVASTEGFESEEE-ILVRLREILDLNKQELINASIRRITFMFGFKD--------------GSYPKYYTFNG-PNYNENETIRHIEPALAFQLELGRLSNFNIKPIFTDNRNIHVYEAVSKTSP----LDKRFFTRGIIRTGHIRDDISIQEYLTSEANRLMSDILDNLEVTDTS----NSDLNHIFINFIAVFDISPEDVEAAFGGFLERFGKRLLRLRVSSAEIRIIIKDPQTGAPVPLRALINNVSGYVIKTEMYTEVKN-AKGEWVFKSLG-KPGSMHLRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLT-----DDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGAPAINKMLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGR-ETESG--FEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQEPGQVWHPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPQGMVGIKFRREKLLDTMNRLDDKYRELRSQLSNKSLA--PEVHQQISKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHQVGEAS------RLEKIARIRSWYPASVDHEDDRQVATWIEENYK-------TLDDKLKGLKLESFAQDLAKKIRSDHDNAIDGLSEVIKMLSTDDKEKLLKTLK--------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32874-1", "uniprot_id": "HFA1_YEAST", "id": "P32874-1", "name": "Acetyl-CoA carboxylase, mitochondrial", "aln": "--------------KGKTITHGQSWGARRIHSHFYITIFTITCIRIGQYKLALYLDPYRFYNITGSQIVRL-----------------------------KGQRPEYRKRIFAHSYRHSSRIGLN------FPSRRRYSNYVDRGNIHKHTRLPPQFIGLNTVESAQP----------------------------------------------------------------------------SILRDFVDLRGGHTVISKILIANNGIAAVKEMRSIRKWAYETFNDEKIIQFVVMATPDDLHANSEYIRMADQYVQVPGGTNNNNYANIDLILDVAEQTDVDAVWAGWGHASENPCLPELLASSQRKILFIGPPGRAMRSLGDKISSTIVAQSAKIPCIPWSGSHIDTIHIDNKTN--FVSVPDDVYVRGCCSSPEDALEKAKLIGFPVMIKASEGGGGKGIRRVDNEDDFIALYRQAVNETPGSPMFVMKVVTDARHLEVQLLADQYGTNITLFGRDCSIQRRHQKIIEEAPVTITKPETFQRMERAAIRLGELVGYVSAGTVEYLYSPKDDKFYFLELNPRLQVEHPTTEMISGVNLPATQLQIAMGIPMHMISDIRKLYGLDPTGTSYIDFKN--------LKRPSPKGHCISCRITSEDPNEGFKPSTGKIHELNFRSSSNVWGYFSVGNNGAIHSFSDSQFGHIFAVGNDRQDAKQNMVLALKDFSIRGEFKTPIEYLIELLETRDFESNNISTGWLDDLILKNLSSDSKLDPTLAIICGAAMKAYVFTEKVRNKYLELLRRGQVPPKDFLKTKFPVDFIFDNNRYLFNVAQSSEEQFILSINKSQCEVNVQKLSSDCLLISVDGKCHTVYWKDDIRGTRLSIDSNTIFLEAELNPTQVISPTPGKLVKYLVRSGDHVFAGQQYAEIEIMKMQMPLVAKSDGVIELLRQPGSIIEAGDVIAKLTLDSPSKANESSLYRGELPVLGPPLIEGSRPNHKLRVLINRLENILNGYHE-----NSGIETTLKELIKILRDGRLPYSEWDSQISTVRNRLPRQLNEGLGNLVKKSVS--------FPAKELHKLMKRYLEEN---TNDHVVYVALQPLLKISERYSEGLANHECEIFLKLIKKYYAVEKIFENHDIHEERNLLNLRRKDLTNLKKILCISLSHANVVAKNKLVTAILHEYEPLCQDSSKMSLKFRAVIHDLASLESKWAKEVAVKARSVLLRGIFPPIKKRKEHIKTLLQLHIKDTGAENIHSRNIYSCMRDFGNLIHSNLIQLQDLFFFFGHQDTALSSIASEIYARYAYGNYQLKSIKIHKGAP-DLLMSWQFSSLRNYL-----------------VNSDGESDEFTKLSKPPSTS-GKSSAN-----SFGLLVNMRALESLEKTLDEVYEQIH-----------------IPEERLSSG--ENSLIVNILSPIRYRSEND-LIKTLKIKLHENERGLSKLKVNRITFAFIAAN--------------APAVKFYSFDG-TTYDEISQIRNMDPSYEAPLELGKMSNYKIRSLPTYDSSIRIFEGISKFTP----LDKRFFVRKIINSFMYNDQKTTEENLKAEINAQVVYMLEHLGAVDIS----NSDLNHIFLSFNTVLNIPVHRLEEIVSTILKTHETRLFQERITDVEICISVECLETKKPAPLRLLISNKSGYVVKIETYYEKIG-KNGNLILEPCS-EQSHYSQKSLSLPYSVKDWLQPKRYKAQFMGTTYVYDFPGLFHQAAIQQWKRYFPKHKLN-----DSFFSWVELIE-QNGNLIKVNREPGLNNIGMVAFEIMVQTPEYPEGRNMIVISNDITYNIGSFGPREDLFFDRVTNYARERGIPRIYLAANSGAKLGIAEELIPLFRVAWNDPSDPTKGFQYLYLAPKDMQLLKDSGKGNSVVVEHKMVYGEERYIIKAIVGFEEGLGVECLQGSGLIAGATSKAYRDIFTITAVTCRSVGIGSYLVRLGQRTIQVEDKPIILTGASAINKVLGTDIYTSNLQIGGTQIMYKNGIAHLTASNDMKAIEKIMTWLSYVPAKRDMSPPLLETMDRWDRDVDFKPAKQVPYEARWLIEGKWDSNNN--FQSGLFDKDSFFETLSGWAKGVIVGRARLGGIPVGVIAVETKTIEEIIPADPANLDSSEFSVKEAGQVWYPNSAFKTAQTINDFNYGEQLPLIILANWRGFSGGQRDMYNEVLKYGSFIVDALVDYKQPILIYIPPFGELRGGSWVVIDPTINPEQMEMYADVESRGGVLEPDGVVSIKYRKEKMIETMIRLDSTYGHLRRTLTEKKLS--LEKQNDLTKRLKIRERQLIPIYNQISIQFADLHDRSTRMLVKGVIRNELEWKKSRRFLYWRLRRRLNEGQVIKRLQKKTCDNKT---KMKYDDLLKIVQSWYNDLDVNDDRAVVEFIERNSK-------KIDKNIEEFEISLLIDELKKKFEDRRGNIV--LEELTRLVDSKRKR---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : ... . : :** ** **.*:*********** :**:*:*:** * ::: ::**.*.**:**.**:***:***:*: ****.*******::**:*:* : *:************* *** * .. : *:*** .** :****::*:****:* :* :****: : . :. :.: ::: :* . : .* .: :*:***:************:*: ::* *::*. * ****:*:*::. :******:******. *:*******:************. :: . .*. **:.*::*.::*************. :. ::************* ***::.*****:****.****:. :.*** :** .* . : ***. * * ** :.*****:*::***** *.::******..********. * :*.*:****** *: *::*: : .::*:***::****:*:*.:**** ****. * * * *.*** ** ..: :: : * *.::.*: * : .: *.:**: . . * . . *::* :. :* . .::.. : : : :* * :: :::**.. :*:: * .:* * *::: *: :.. * .:* * :*: : :*:.***:: *..* *: ** *****:*** *.*.: . * : :::.*: : .* ::. : **.** . .: . * : : : . . * : : ** :. ::.::: **: ** * . :::: .*:* ::: : : : **:::: .::. .:. :.: .: .:* .*: : . .::.:* ** *: : :. : :* .: :: .: :**::* ** *: ::.. * .. :: : : .:..*. .**:::*.:*: . *. . * :::: :: : . . : ** *: :: * *: *.: .: * ::* * ** * : :: : :: ::* * . :: .: : : : . . : : :: : : . :: * . :.*:** *:::* . .: * *:::*: ***.:: .: : .: : .:::: . :: * *** * **. . : * * * : : ::.* .. .:* ****:.* ... : :* . :: . ** : *: ..*: : :. .:* : * *** :. . * * .. ::. . : . : ** .*: ** **::*: ****:**.* :*:* *. ..:: : : . .:* .::* ** * ****:.: . :**** **:.:*:.**:*. ***** :** :* :.:: ** :****::.****::*:***: :*::** *. :* **::****:.:. : *** **.*: *. *:* ::*:* * *: :*:*** :* ** ::.*: ****::***:*:******.**::.. :**** *:**:** .:*:** *:** ***.:**::* . *: .: .:: *:**:* *:: . * :* ::* *: . .*: **:: *: . : *:** .*: * : **: *:.*******:* **:.***:::* :****** :* :::.****.*:*::** *:*:**. * **::::********* :**:::::*:*::***.* : :*:::*:** .*****:*.*:*. **. ** *** ::*..****:* * **::.:.::.*: *:* * * . : :: .:: * *: :* ::::****** . ** * * . : * :* :::***** * * ::: : . . :.:. :. : *.: :. ::: . . . . : . .. : : : : : . : ", "identical_positions": 680, "similar_positions": 701, "identity": "26.81%" }, { "cls_id": "homologset.agr.RGD:621249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VD04-1", "uniprot_id": "GRAP1_MOUSE", "id": "Q8VD04-1", "name": "GRIP1-associated protein 1", "aln": "MAQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQKALSKSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQLEQLELENRQLKEGVPGA----AGAHVDGELLRLQAENTALQKNMAALQERYGKEAVRPSAVGEGQGDPPGDVLPTPLAPMPLAEVELKWEMEREEKKLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQD-------------------------------QIQTAKTQELNMLREQTSELASELQHRQAEYEELMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQDLQEARKSAEKRKVMLDELAMETLQEKSQHKEELGAVRLRHEKELLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQQEQEETLKLCREEHAAELKGKDEELQNVREQLQQAQEERDGHVKTISNLKQEVKDTVDGQRILEKKGSAVLKDLKRQLHLERKRADKLQERLQEILTNSKSRTGLEELVLSEMNSPSRTQTGDSSSVSSFSYREILKEKESSAIPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGSPDPDLEPGEAN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JHZ4-1", "uniprot_id": "GRAP1_RAT", "id": "Q9JHZ4-1", "name": "GRIP1-associated protein 1", "aln": "MAQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQKALSKSKKAQEVEVLLSEKEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQLEQLELENRQLKEGVPGA----AGPHVDGELLRLQAENTALQKNMAALQERYGKEAVRPSAVSEGQGDPPGDVLPISLSPMPLAEVELKWEMEREEKKLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSSQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQNTELAAELKHRQADYEELMGQKDDLNSQLQESLRANSRLLEQLQEMGQEKEQLIQDLQEARKSAEKRKVMLDELAMETLQEKSQHKEELGAVRLRHEKEMLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQAQVHSMDGAKGWFERRLKEAEESLLQQEQEQEETLKQCREQHAAELKGKEEELQNVRDQLQQAQEERDGHVKTISNLKQEVKDTVDGQRILEKKGSAVLKDLKRQLHLERKRADKLQERLQEILTNSKSRTGLEELVLSEMNSPSRTQTGDSSSVSSFSYREILKEKESSAIPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGSPDPDLEPGEAN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4V328-1", "uniprot_id": "GRAP1_HUMAN", "id": "Q4V328-1", "name": "GRIP1-associated protein 1", "aln": "MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALSKSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFSAVSEGQGDPPGGLAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGPPDPDLEPGETS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************:***********************:***********************************:*******************************:**** **:*****..** **. ******************:*********** : ***.********.: * *:**************:***:****************************************************************** ******************************************** ****************.: **:**:::**:**:****************************:******* *:************.******************************:****************************************.**:****************************** **:*****:** ***:********:****:**:**:******* *:****.*********************.***********************:********:***********************:*********:******:*************************************************************************************************************************************************.*********:.", "identical_positions": 745, "similar_positions": 48, "identity": "88.59%" }, { "cls_id": "homologset.agr.RGD:621251", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET61-1", "uniprot_id": "C1QR1_RAT", "id": "Q9ET61-1", "name": "Complement component C1q receptor", "aln": "MVTSTGLLLLLGLLG-QLWAGAAADSEAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQEALAQLLKTKAPSETKIGKFWIGLQREKGKCTYHDLPMKGFSWVGGGEDTTYSNWYKASKSSCISKRCVSLILDLSLKPHPSHLPKWHESPCGTPDAPGNSIEGFLCKFNFKGMCSPLALGGPGQLTYTTPFQATTSSLKAVPFASVANVVCG--DEAESKTNYYLCKETTAGVFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPCTGGGMCHSVPLSENYTCHCPRGYQLDSSQVHCVDIDECEDSPCDQECINTPGGFHCECWVGYQSSGSKEEACEDVDECTAAYSPCAQGCTNTDGSFYCSCKEGYIMSGEDSTQCEDIDEC---LGNPCDTLCINTDGSFRCGCPAGFELAPNGVSCTRGSMFSELPARPPQKEDKGDGKESTVPLTEMPGSLNGSKDVSNRAQTTD-LSIQSDSSTASVPLEIEVSSEASDVWLDLGTYLPTTS-GHSQPTHEDS-VPAHSDSDTDGQKLLLFYILGTVVAISLLLALALGLLIYLKRKAKKEEIKEKKAQNAADSYSWIPERAESRAPENQYSPTPGTDC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89103-1", "uniprot_id": "C1QR1_MOUSE", "id": "O89103-1", "name": "Complement component C1q receptor", "aln": "MAISTGLFLLLGLLG-QPWAGAAADSQAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQQALTQLLKTKAPLEAKMGKFWIGLQREKGNCTYHDLPMRGFSWVGGGEDTAYSNWYKASKSSCIFKRCVSLILDLSLTPHPSHLPKWHESPCGTPEAPGNSIEGFLCKFNFKGMCRPLALGGPGRVTYTTPFQATTSSLEAVPFASVANVACG--DEAKSETHYFLCNEKTPGIFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPCTGGGMCHSVPLSENYTCRCPSGYQLDSSQVHCVDIDECQDSPCAQDCVNTLGSFHCECWVGYQPSGPKEEACEDVDECAAANSPCAQGCINTDGSFYCSCKEGYIVSGEDSTQCEDIDECSDARGNPCDSLCFNTDGSFRCGCPPGWELAPNGVFCSRGTVFSELPARPPQKEDNDDRKESTMPPTEMPSSPSGSKDVSNRAQTTG-LFVQSDIPTASVPLEIEIPSEVSDVWFELGTYLPTTS-GHSKPTHEDS-VSAHS--DTDGQNLLLFYILGTVVAISLLLVLALGILIYHKRRAKKEEIKEKKPQNAADSYSWVPERAESQAPENQYSPTPGTDC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPY3-1", "uniprot_id": "C1QR1_HUMAN", "id": "Q9NPY3-1", "name": "Complement component C1q receptor", "aln": "MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKLSAAEAQNHCNQNGGNLATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKGKCLDPSLPLKGFSWVGGGEDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPSRLPKWSEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEGTPKATPTTSRPSLSSDAPITSAPLKMLAPSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLLLALALGLLVYRKRRAKREEKKEKKPQNAADSYSWVPERAESRAMENQYSPTPGTDC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * **:*** ** * **:.**::**** ******** *********::**:**********:***:***..*:***: :*. :::.***********:* .**::***********.****:* :.*** ******:**** **:**** *.***:* :**..****:***.***** ********::*******:*:***:******.***.** *: :::::*:**:*.:..:*.************:**.******:*********** ************************.** **. * * .:****:** ********:.***:***:**** *:*:** *.*:*******:..*. * **:*****: . ******* ******:***:***:::***.***:*:*** * **:**:**:***:*** .*: ****** *: *.: *: **::**:.: : **:* : ... *.:...: : **. :.** . :*.**:: .* ..** : . : .*:: * .:*: ** *.::. .****:************* ***.****:*:* **:**:** ****.*********:******:* ************", "identical_positions": 409, "similar_positions": 152, "identity": "62.73%" }, { "cls_id": "homologset.agr.RGD:621252", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28184-1", "uniprot_id": "MT3_MOUSE", "id": "P28184-1", "name": "Metallothionein-3", "aln": "MDPETCPCPTGGSCTCSDKCKCKGCKCTNCKKSCCSCCPAGCEKCAKDCVCKGEEGAKAEAEKCSCCQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P37361-1", "uniprot_id": "MT3_RAT", "id": "P37361-1", "name": "Metallothionein-3", "aln": "MDPETCPCPTGGSCTCSDKCKCKGCKCTNCKKSCCSCCPAGCEKCAKDCVCKGEEGAK--AEKCSCCQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25713-1", "uniprot_id": "MT3_HUMAN", "id": "P25713-1", "name": "Metallothionein-3", "aln": "MDPETCPCPSGGSCTCADSCKCEGCKCTSCKKSCCSCCPAECEKCAKDCVCKGGEAAEAEAEKCSCCQ", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:******:*.***:*****.*********** ************ *.*: ********", "identical_positions": 57, "similar_positions": 7, "identity": "83.82%" }, { "cls_id": "homologset.agr.RGD:621253", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97321-1", "uniprot_id": "SEPR_MOUSE", "id": "P97321-1", "name": "Prolyl endopeptidase FAP", "aln": "-------------------------------------------------------------------------------------------MKTWLKTVFGV--------------------------TTLAALALVVICIVLRPSRVYKPEGNTK------RALTLKDILNGTFSYKTYFPNWISE-QEYLHQSEDDNIVFYNIETRESYIILSNSTMKSVNATDYG----LSPDRQFVYLESD----------------------------------------------------------------YSKLWRYSYTATYYIYDLQNGEFVRG----------YELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRP-GDPPFQITYTGRENR-------IFNGIPDWVYE--EEMLATKYALWWSPDGKFLAYVEFNDSDIPIIAYSYYGD------------GQYPRTINIPYPKAGAKNPVVRVFIVDTTYPHHVGPMEVPVPEMIASSDYYFSWLTWVSSE--RVCLQWLKRVQNVSVLS------------------------------ICDFREDWHAWECPKNQEHVEESRTGWAGGFFVSTPAFSQDATSYYKIFSDKDG----YKHIHYIKDTVENAIQITSGKWEAIY--IFR-VTQDSLFYSSNEFEGYPGRRNIYRISIGNSPPS----------KKCVTCHLRK--------------------------ERCQYYTASFS--------YKAKYYALVCYGPGLPISTLHDGRTDQEIQVLEENK-ELENSLRNIQLPKV-EIKKLKDGGLTFWYKMILPPQFDRSK---KYPLLIQVYGGPCSQSVKSVFAVNWITYLASKEGIVIALVDGRGTAFQGDKFLHAVYRKLGVYEVEDQLTAVRKFIEMG--FIDEERIAIWGWSYGGYVSSLALASG-TGLFKCGIAVAPVSSWEYYASIYSERFMGLPTKDDNLEHYKNSTVMARAEYFRNVD-YLLIHGTADDNVHFQNSAQIAKALVNAQVD-FQAMWYSDQNHGISSGRSQNHLYTHMTHFLKQCFSLSD-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEN0-1", "uniprot_id": "A0A8I6AEN0_RAT", "id": "A0A8I6AEN0-1", "name": "", "aln": "-------------------------------------------------------------------------------------------MKTWLKTVFGV--------------------------TTLVALALVVICIVLRPSRVYSPEGNTG------RSLTLKDILNGTFSYKTYFPNWISE-QEYLHQSEDDNIVFYNIETRESYIILSNSTMKSVNATDYG----LSPDRQFIYLESD----------------------------------------------------------------YSKLWRYSYTATYYIYDLQNGEFVRG----------YELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRP-GDPPFQITYTGRENR-------IFNGIPDWVYE--EEMLATKYALWWSPDGKYLAYVEFNDSDIPIIAYSYYGD------------GQYPRTINIPYPKAGAKNPIVRVFIVDTIYPHHVGPIEVPVPEMIASSDYYFTWLTWVTNE--RVCLQWLKRVQNVSVLS------------------------------ICDFREDWHAWDCPKNQEHIEESRTGWAGGFFVSTPAFSQDAASYYKIFSDKDG----YKHIHYIKDTVENAIQITSGKWEAIY--IFR-VTQDSLFYSSNEFEGYPGRRNIYRISIGNSPPS----------KKCVTCHLRK--------------------------ERCQYYTASFS--------YKAKYYALICYGPGLPISTLHDGRTDQEIQVLEENK-ELENALRNIQLPAV-EIKKLEDGGMTFWYKMILPPQFDRSK---KYPLLIQVYGGPCSQSVKSVFSVNWITYLASKEGIVVALVDGRGTAFQGDKFLHAVYRKLGVYEVEDQLTAVRKFIEMG--FIDEGRIAIWGWSYGGYVSSLALASG-TGLFKCGIAVAPVSSWEYYASIYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVD-YLLIHGTADDNVHFQNSAQIAKALVNAQVD-FQAMWYSDQNHGISSGRSQNHLYTHMTHFLKQCFSLSD-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12884-1", "uniprot_id": "SEPR_HUMAN", "id": "Q12884-1", "name": "Prolyl endopeptidase FAP", "aln": "-------------------------------------------------------------------------------------------MKTWVKIVFGV--------------------------ATSAVLALLVMCIVLRPSRVHNSEENTM------RALTLKDILNGTFSYKTFFPNWISG-QEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYG----LSPDRQFVYLESD----------------------------------------------------------------YSKLWRYSYTATYYIYDLSNGEFVRG----------NELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRP-GDPPFQITFNGRENK-------IFNGIPDWVYE--EEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGD------------EQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDE--RVCLQWLKRVQNVSVLS------------------------------ICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDG----YKHIHYIKDTVENAIQITSGKWEAIN--IFR-VTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPS----------KKCVTCHLRK--------------------------ERCQYYTASFS--------DYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENK-ELENALKNIQLPKE-EIKKLEVDEITLWYKMILPPQFDRSK---KYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMG--FIDEKRIAIWGWSYGGYVSSLALASG-TGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVD-YLLIHGTADDNVHFQNSAQIAKALVNAQVD-FQAMWYSDQNHGLS-GLSTNHLYTHMTHFLKQCFSLSD-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0C4DHM8-1", "uniprot_id": "A0A0C4DHM8_DROME", "id": "A0A0C4DHM8-1", "name": "Dipeptidyl peptidase 4", "aln": "--------------------------------------------------MHTNMTSDRSGGGGGSWRLPPDETLQVQDPKQKDHDFDFDEGHNWRSIILSL--------------------------LVISFVVSGIVTAIYLLGYVDELLYWSG------RRMILDEYLQGDLIPRRLPSSWVTT-QKYVFQSDDGSLAVLDTTTNLVKVLVTNHTLRQLNVRRYL----CSSDLKYVLFTHN----------------------------------------------------------------VKKNFQKSFTAFYTIYDVTNDHHTPVK----LKDTLKVQRTRLQYASWLGNTTAIIFVVKNDIFIRQSPLVEEDIRITSSGHENH-------IYNGVPDWLYQ--EEIFETPEAIWTSSDGTHFMYALFNDTNVGMMTYPWLSSGALFSGSGIFSGSIFPETKMVRFPTPGTTNPEVELWAVDITNLSDIQKFNIKPPATIYGQDYYLTSAGWISDSNCQVSVVYMGRSQNYSVIS------------------------------LCSKEEDWKCLEVHSERAPEDEWLDIFP------HPVFSSDGSSFLFLANIQESENYQFTHIKHVMISQRRISVISHGRYEVTK--ILCWDTINHKVYFMATQDKKPGQRHLYSVQDPIHDDIRK------VEPQCITCDLGDDLW-----------------SSRYYYTNCTHFEAFITPSLGVATNYGIEFYILECQGPGLPVSGVHMQTTHSLVKILYDTRPFYTERLQKLALPTQRSFEVPLPHGGRAQVQLLLPPSWREELRDAAFPVIVEVNGRPGSESVSEKFKIDWGTYMSSRNDVVYIRLDVRGSKGQSK---KTLYRHLGGVEVLDQISVIGYLLDTIG-FLDETRVGMWGWGYGGYVTSMALGTQ-QDVFKCGIAVSPTADWLYST--FTERILGLPAEN--FKGYVEADATQRARLIKSNS-YFLIHGLADTTAPFVHGVQLAKSLTSANIL-FRYQTYADEGHDLS--GVLEHVYSSMEQYFAECLSLDPDDTKPEVDNSIVPAE----------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IR04-1", "uniprot_id": "Q8IR04_DROME", "id": "Q8IR04-1", "name": "Venom dipeptidyl peptidase 4", "aln": "-------------------------------------------MVEIQKPHSALKRPSLKRETVVVNNSAPTIKKVTLVPKDEELVAISPERRNWRGIFIAL--------------------------LVIAAVFSLIIFSIFLLSPEDEGLRIRG------RRMLPSDILGRSLQWKPFNGTWSNG-RELIYRDPTGGLSILNMADLTTRILMTNSTFRQLNAESFL----VAPDQKYVLLQSDSNAEGSRHHVYEVQTANTFPLGPTENIAEAPRLQHVVWAPANPPPPLGAPPPSGASGASGASGASTTTMAPLPSGSIILNSLAGAANGPAS----AGASGSSAPNPNGKAGGYNLNQAIAFVHHNDIYYKPKVQGELVCRITQTGSGSLEGESTGVVFNGVPDWMYENVPELESRRSSMEFSPDGLFLAFLSYNDSEVNEYKYTWMGDD-----------IKYPAVMSQRYPKTGSRNPNVTVNVVNLSVIKYIFPTQIKLPSELS-NGSYVGGLTWASSTDLSVTVTNREQTKATTVLCRAPHFHCQAVHTEVTINDGWVLPSERPIFSVRNQGHNRLGKMVQNAEEIQAESQNVNVTDGQTHTTHEISNGGYLLKRLPVRDGEHGHYRHVVFISSLDRRPVPLTMGRFEVTE--IVGWDEPHEIVYFMAAPEKRPGERHLYKISLKLNVTESNRTYITSTSPTCLTCDNTESTYRLHRARISQRGDRWEDIVARLEPDDCLYDIPKNCLFNRVQFSQDYSYYVQECLGPEAPSVYLVETASNDKIYVLNAGD-VLRHRLSQLAIPQSRTFSVEIRHGFHAQVRLFLPPGMREEE-DVAFPLVLHVDASPGSQLVTERFHVDWNWYLASQRSFIVAQIDGRGSGFQGELLRTQVHGKLGTVEVEDQLGVLTYLRDNLK-FIDPLRICAFGWGYGGYASSMMLIDDSQQVLQCAVAINPIVNFGFHYSFFTERYI--PLKGDYLRALQEADLTMKAGNIKGRN-LMLMHGTADTLVHQEHTLMLVRALVEQQVK-FRHQVYPDEDHAIA--RSLSHVYKTMEWYFDECFGPVDDNEWDPTGLFVFKQXLRPPYDPYDEDPLANQLSDIDIGPATDAHPDADAAGDSAGSNLSTLLTATTTSASLSALDELDNRLQALDLITSSTATTLSKVAGKLCNYSSKRRLHQSEAVLAQKSRILQH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33894-1", "uniprot_id": "STE13_YEAST", "id": "P33894-1", "name": "Dipeptidyl aminopeptidase A", "aln": "MSASTHSHKRKNSHLFPQRKSSNSSMDKPFFPNNDSVANTDPQSNENGHTINEIRPTEATIDVTDVPQTPFLQEQYSMRPRRESFQFNDIENQHHTHSFFSVNKFNRRWGEWSLPEKRSYVLVFTLIALSVLVLLVILIPSKLLPTKITRPKTSAGDSSLGKRSFSIENVLNGDFAIPEDTFHFIDPPQRLLGQDSDPGLYFTTKEIDGHTNFIAKQLFDETFEVNLGGNRFLYEGVEFTVSTVQINYKLDKLIFG---------------------------------------------------TNLESEFRHSSKGFYWIKDLNTGNIEPILPPEKSDDNYELGLSKLSYAHFSPAYNYIYFVYENNLFLQQVN-SGVAKKVTEDGSKDI--------FNAKPDWIYE--EEVLASDQAIWWAPDDSKAVFARFNDTSVDDIRLNRYTNMN----------EAYLSDTKIKYPKPGFQNPQFDLFLVNLQNGIIYSINTGGQKDSILYNGKWISPDTFRFEITDRNSKILDVKVYDIPSSQ---------------------------MLTVRNTNSNLFNGWIEKTKDILSIPP----------KPELKRMDYGYIDIHADSRG---FSHLFYYPTVFAKEPIQLTKGNWEVTGNGIVGYEYETDTIFFTAN-EIGVMSQHLYSISLTDSTTQN----------TFQSLQNPSD-------------------------KYDFYDFELSSSARYAISKKLGPDTPIKVAGPLTRVLNVAEIHDDSILQLTKDEK--FKEKIKNYDLPITSYKTMVLDDGVEINYIEIKPANLNPKK---KYPILVNIYGGPGSQTFTTKSSLAFEQAVVSGLDVIVLQIEPRGTGGKGWSFRSWAREKLGYWEPRDITEVTKKFIQRNSQHIDESKIAIWGWSYGGFTSLKTVELDNGDTFKYAMAVAPVTNWTLYDSVYTERYMNQPSEN--HEGYFEVSTIQNFKSFESLKRLFIVHGTFDDNVHIQNTFRLVDQLNLLGLTNYDMHIFPDSDHSIRYHNAQRIVFQKLYYWLRDAFAERFDNTEVLHL-----------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:.: : :: * : .: * : : :. : :. .: . :::: : . . :: : . .. : .: : :* .*::: : ::* * . :*. ***:*: *: :: :.:. : :**:.: . : :*..* ** . : :: : .. :. : . : . : . : . . . . . . .. :: *.:*. *. .: : :::* :. : . . : ** : .. : : . : : :* : *. . :*:::.: . * *: . : : : * ..: :: **: :. :** * * . : : .:* :: :**.***:.: : :: .:*: * .: ::** : * :. . : . :.. . :::** * . : :. * : : :.*..* : :: : :: :.:. ", "identical_positions": 53, "similar_positions": 198, "identity": "4.4%" }, { "cls_id": "homologset.agr.RGD:621254", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AQL3-1", "uniprot_id": "A0A8I6AQL3_RAT", "id": "A0A8I6AQL3-1", "name": "", "aln": "---------------------MGRHLALLLLLLLFLQHFGDGDGSQRLEPTPS------LQFTHVQYNVTVHENSAAKTYVG--HPRKMGIYILDPSWEIRYKIISGDNENLFKAEEYVLGDFCFLRIRTKGGNTAILNREVRDHYTLVIKAVEKVTD-----AEARAKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDMFAIHPTSGVVVLTGRLDVLETQRYELEILAVDRGMKLYGSSGVSSLAKLTVHVEQANECAPEITAVTLSPSELDKDP-TYAIITVEDCDQGANGEIASLSIVAGDLLQQFKTVRSFPGSKAFKVKAVGGVDWDSHPYGYNLTVQAKDKGTPPQFSPVKVIHVISPQFRAGPVKFEMDVYRAEISEFAPPHTPVVLVKAIP----SYSHLRYVFKSTPGKPKFGLNHNTGLISILEPIKRQHTTHFELEVTTSDRR-------ASTKVVVKVVGTNSNPPEFTQTSYKASFDENAPVGTPVMRVSAVDPDEGENGYVTYSIANLNHVPFVIDHFTGAVSTSENLDYELMPRVYMLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFEKTNCEGTIPRDLGVGEQITTVSAIDADELQLVRYQIEAGNELDLFGLNPSSGVLSLKHSLMDGLGAKVSFHSLRITATDGENFATPLYINLTVAAS---------RKPVNLRCEETGVAKMLAEKLLQANKLHHQGDAEDIFFDS------HSVNAHAPQFRGSLPTGIEVKEDLPVGASILFMNATDLDSGFNGKLVYAISGGNDDSCFTVDMETGMLKVLSPLDREVTDKYTLNITVYDLGIPQRAAWRLLDVTVLDANDNAPEFLQESYFVEVSEDKEINSEIIQVEATDKDLGPSGHVTYAILTDTEKFAIDRVTGVVKIIQPLDREVQRVHYLKIEARDQATEEPWLSSTVLLKVSLDDVNDNPPRFIPPSYSVKVREDLPEGTIIMWLEAHDPDVGQSSQVRYSLLDHGEGH--FDVDKLSGAVRIVQQLDFEKKQLYNLTVRAKDKGKPASLSSTGYVEVEVVDVNENLHAPVFSSFVEKGTVKEDVPMGSSVMTVSAHDED-TGRDGEIRYSIRDGSGVGVFRIDEETGVIETSDRLDRESTSHYWLTVYATDQGVVPLSSFIEVYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSSDKLTYRITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGVPPRSTIARVIVKILDENDNRPQFLQKFYKIRLPEREKADGDRSA-KREPLYRVIAADKDEGPNAELSYSIEEGNEHGRFSIEPKTGVVSSKKFSAAGEYDILSIKAIDNGRPQKSSTTRLHIEWISK-PKPSLEPISFEES-VFSFTVMESDPVAHMIG-VISVEPPGMPLWFDIIGDALAREAFYIFQMTCDLNCTAEGGNYDSHFDVDKGTGTIIVAKPLDAEQKSSYNLTVEATDGTSTILTQVLIKVIDTNDHRPQFSTSKYEVSVPEDTEPETEILQISAVDRDEKNKLIYTLQSSIDPASLKKFRLDPATGALYTSEKLDHEAIHQHVLTVMVRDQDVPVKRNFARIIVNVSDMNDHSPWFTSSSYEGRVYESAAVGSVVLQVTALDRDKGRNAEVLYSIESGNIGNSFTIDPILGSIKTARELDRSHQVDYDLMVKATDKGEPPMSEMTSVRISVTVADNASPKFTSKEYSAEISEAIRIGSFVGMVSAHSQSSVMYEVKDGNIGDAFNINPHSGSIVTQRALDFETLPIYTLTVQGTNMAGLSTNTTVVVHIQDENDNPPAFTRAEYSGFISESASVNSVVLTDKNVP---LVIRATDADRESNALLVYQIVEPSVHNYFAIDPTTGAIHTVLSLDYEETRVFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFSKSLYEASLLLPTYKGVNVITVNATDADSRAFSQLIYSITKGNIGEKFSMDHKTGTIAIQNTTQLRSR----YELTVRASDGRFTSVASVRINVKESRESPLKFTQDAYSAVVKENSTEAKTLAVITAIGNPINEPLFYRILNPDRRFKISHTSGVLSTTGIPFDREQQETFVVVVEVT-----KEREPSAVAHVVVKVTVEDQNDNAPVFVNLPYYAVVKVDAEVGHVIRHVTAIDRDSGRNGDVHYYLKEHH-DHFEIG-PSGDISLKKQFEHDTLNKEYLVTVVAKDGGNPAFSAEVLVPITVMNKAMPVFEKAFYSAEIPENVQTHSPV-VHVQANSPEGLKVFYSITDGDPFSQFTINFNTGVINVIAPLDFESHPAYKLSIRATDSLTGAHAEVFVDIVVEDINDNPPVFVQQSYSTTLSEASVIGAPILQVRATDSDSEPNRGISYQLIGNHSKS-HDHFHIDSHTGLISLVRALDYEQFQQHKLLVRAVDGGMPPLSSDVVVTVDVTDLNDNPPLFEQQVYEARISEHAAHGHFVMCVKACDADRSDLDRLEYSILSGNDHKSFVIDGETGIITLSNPRRHTLKPFYSLNVSVSDGVFRSSARVNVTVMGGNLHSPVFHQNEYEVELAENAPLHTLVVQVKATDRDSGIYGHLTYHLVNDFAKDRFYVNDG-GQVFTLERLDREAPAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRSTKYEVNVGSSAAKGTSVVKVFASDADEGSNADVTYAIEADSES--VEENLEINQLTGLITTKESLIGLENEFFTFFVRAVDNGSPPKESVVPVYVKILPPEVQLPRFSEPFYTYSISEDMPIGTEIDLIRVEHSGTVLYTLVKGNTPESNRDEFFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTLDDYEVVASIDVSIQVKDANDNSPVLESNPYEAFIVENLPAGSRVIQVRASDLDSGVNGQVMYSLDQSQ-DADIIESFAINMETGWITTLKELDHEERASYQIKVVASDHGEKVQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPPGGVIAILSTTDADSEEINRQVSYFITGGDALGQFAVENMQNDWRVYVKKPLDREQKDSYLLTVTATDGTFSSKARVEVKVLDANDNSPVCERTAYSDAIPEDALPGKLVMQVSATDADIRSNAEITYTLFGSGAEKFKLNPDTGELRTLALLDREEQAVYHLLVKATDGG--GRSCQATIVLTLEDVNDNTPEFTADPYAITVFENTEPGTPLTRVQATDADAGLNRKISYSLLDSADGQFSINEQSGILQLEKHLDRELQAVYTLTLKAADQGLPRKLTATGTVVVSVLDINDNPPVFEYREYGATVSEDIVIGTEVLQVYAASRDIEANAEITYAIISGNEHGKFSIDSKTGAIFIIENLDYESSHGYYLTVEATDGGTPSLSDVATVNINITDINDNSPVFSQDSYTTVVSEDAALEQPVITIMADDADGPSNSHILYSIIEGNQGSPFTIDPVRGEIKVTKPLDRETISGYTLTVQAADNGNPPRVNTTTVNIDVSDVNDNAPLFSRDNYSVIIQENKPVGFSVLKLVVTDKDSSHNGPPFSFAIVSGNDDNMFEVNQHGVLLTAATVKRKVKDHYLLHVKVADNGKPQLSSLTHIDIRVIEESIHPPAILPLEIFITASGEEYSGGVIGKIHATDQDVYDTLTYSLDP------HMDGLFSVSSTGGKLIAHRKLDIGQYLLNVSVTDGKFTTVADITVHIQQVTQEMLNHTIAIRFANLTPEEFVGDYWRNFQRALRNILGIRKNDIQIVSLQP--------------SEPHS-HLDVLLFVEKS-----GGTQISTKQLLHKINSSVTDIEEIIGVRILDVFQKLCAG--LDCPWKFCDEKVSVDENIMSTHSTARLSFVTPRHHRTAVCLCK----DGTCPPVHQGCEDNPCPAGSECVADPREEKYSCVCPGGGFAKCPGSSS---------------ITFTGSSFVKYRLMENENRLEMK----LTMRLRTYSSHAVVMYARG-TDYSILEIHTGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVSLEVEGNYAKLVLDEVHTASGTAPGALKTLNLDNYVIFGGHLRQQGTKHGRNTQVANGFRGCMDSIYLNGQELPLNNKPR-AYAHIEEWVDLAHGCLLT----ATEDCSSNPCQNGGVCNPSPTGGYYCKCSALHAGTYCEVSVNPCSSNPCLYGGTCMVDN-GGFVCQCRGLYTGQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECAGNPCRNGALCENTHGSYHCNCSQEYRGKHCED--ATPNHYVSTPWNIGLAEGIGIIVFIAGIFLLVVVFVLCRKMISRKKKHQAEPEDKR---LGPTTAFLQRPYFDSKPSKNIYSDIPPQVPVRPISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPESMHGHRKAVAVCSVAPNLPPPPPSNSPSDSDSIQKPSWDFDYDAKVVDLDPCLSKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDDNASIVTVTHLVNAVVDTVNKEESLAAPDLSKPRGYHWDTSDWMPS--VPLPDIQEFPNYEVIDEHTPLYSADPNAIDTDYYPGGYDIESDFPPPPEDFPAPDELPPLP--PEFSDQFESIHPPR---DMPAAGSLGSSSRNR----QRFNLNQYLPNFYPVDMSEPQKQGAGENSTCREP---YTPYPPGYQRNFEAPTIENMPMSVYTSTASCSDVSACCEVESEVMMSDYESGDD--GHFEEVTIPPLDSQ--QHTEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A087WRT4-1", "uniprot_id": "A0A087WRT4_MOUSE", "id": "A0A087WRT4-1", "name": "", "aln": "---------------------MGRHLTLLLLLLLFLQQFGDSDGSQRLEPTPP------IQFTHFQYNVTVHENSAAKTYVG--HPRKMGIYILDPSWEIRYKIVSGDSENLFKAEEYVLGDFCFLRIRTKGGNTAILNREVRDHYTLIVKAVEKATD-----AEARAKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDVFAIHPTSGVVVLTGRLDFLETQLYELEILAADRGMKLYGSSGVSSLAKLTVHVEQANECAPIITAVTLSPSELDKDP-TYAIITVEDCDQGANGEIASLSIVAGDLLQQFKTVRSFPGSKAFKVKAVGAVDWDSHPYGYNLTLQAKDKGTPPQFSPVKVVHIISPQFRAGPVKFEMDVYRAEISEFAPPHTPVVLVKAIP----SYSHLRYVFKSAPGKPKFGLNHNTGLISILEPIRRQHTSHFELEVTTSDKR-------ASARVVVKVLGTNSNPPEFTQTSYKASIDENAPIGAAVTRVSAMDPDEGENGYVTYSIANLNHVPFVIDHFTGTVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFERINCEGTIPRDLGVGEQITTVSAIDADELQLVRYQIEAGNELDLFGLNPSSGVLSLKHSLTDGLGAKVSFHSLRITATDGENFATPLYINLTVAAS---------RKPVNLQCEETGVAKMLAEKLLQANKLHSQGDVEDIFFDS------YSVNTHTPQFGVTLPTGIEVKENLPVGANILFMNATDLDSGFNGKLVYAISGGNDDSCFTIDMETGVLKVLSPLDREVMDKYTLNITVYDLGIPQRAAWRLLDVTVLDANDNAPEFLQESYFVEVSEDKEVNSEIIQVEATDKDLGPSGHVTYAILTDTEKFSIDSMTGVVKIIQPLDREVQPVHYLKIEARDQATEEPRLFSTVLLKVSLDDVNDNPPRFIPPNYSVKVREDLPEGTIIMWLEAYDPDVGQSSQVRYSLLDHGEGH--FDVDKLSGAVRIVQQLDFEKKQLYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHTPVFSSFVEKGVVKEDVPTGSSVMTVSAHDED-TGRDGEIRYSIRDGSGIGVFRIDEETGVIETSDRLDRESTSHYWLTVYATDQGVVPLSSFIEVYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLTYRITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGVPPRSTIARVIVKILDENDNRPQFLQKFYKIRLPEREKADGDRSASKREPLYRVIAADKDEGPNAELSYSIEEGNEHGRFSIEPKTGVVSSKKFSAAGEYDILSIKAVDNGRPQKSSTTRLHIEWISK-PKPSSEPISFEES-VFSFTVMESDPVAHMIG-VISVEPPGMPLWFDIIG-----------------------GNYDSHFDVDKGTGTIIVAKPLDAEQKSSYNLTVEATDGTTTILTQVLIKVIDTNDHRPQFSTSKYEVAVPEDTEPEVEILQISAVDRDEKNKLIYTLQSSIDPASLKKFRLDPATGALYTAEKLDHEAIHQHVLTVMVRDQDVPVKRNFARIVVNVSDKNDHAPWFTSPSYDGRVYESAAVGSVVLQVTALDKDKGRNAEVLYSIESGNIGNSFTIDPILGSIKTARELDRSHQVDYDLMVKATDKGDPPMSEMTSVRIAVTVADNASPKFTSKEYSAEISEAIRIGSFVGMVSAHSQSSVMYEIRDGNMGDAFNINPHSGSIITQRALDFETLPMYSLTVQGTNMAGLSTNTTVVVHVRDENDNPPVFTQAEYSGFISESASVNSVVLTDRNVP---LVIRATDADRESNALLVYQIVEPSVHNYFAIDPTTGAIRTVLSLDYEETHAFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFSKSLYEVSLLLPTYRGVNVITVNATDADSKAFSQVMYSITEGNIGEKFSMDHKTGTIAIQNTTQLRSR----YELTVRASDGRFTSMASVKINVKESRESPLKFTQDAYSAVVKENSTEARTLAVITAIGNPLNEPLFYRILNPDRRFKISHTSGVLSTTGIPFDREQQETFDVVVEVT-----KEHEPSAVAHVVVKVTVEDQNDNAPVFVNLPYYAVVKVDAEVGHVIRYVTAIDRDSGRNGDIHYYLKEHH-DHFQIG-PSGDISLKKQFEHDTLNKEYLVTVVAKDGGSPAFSAEVLVPITVMNKAMPVFEKAFYSAEIPENIQMHSPV-VHIQANSPEGLKVFYSITDGDPFSQFTINFNTGVVNVIAPLDFESHPAYKLSVRATDSLTGAHAEVFVDIIVEDINDNPPVFVQPSYSTTLSEASVIGTPVLQVRATDSDSEPNRGISYQLIGNHSKS-HDHFHIDSNTGLISLVRALDYEQSQQHRIFVRAVDGGMPALSSDVVVTVAVTDLNDNPPLFEQQVYEARISEHAAHGHFVMCVRACDADSSDLDKLEYSILSGNDHKSFIIDRETGIITLSNLRRHTLKPFYSLNVSVSDGVFRSSARVNVTVMGGNLHSPVFHQNEYEVELAENAPLHTLVVQVKASDRDSGIYSHVTYHIVNDFAKDRFYVNDR-GQIFTLEKLDRETPAEKVISIRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRSTKYEVNIGSSAAKGTSVVKVFASDADEGSNADVTYAIEADSES--VKENLEINKLTGLITTKESLIGLENEFFTFFVRAVDSGSPPRESVVPVYIKILPPEVQLPRFSEPFYTYTISEDTPIGTEIDLIRVEHGGAVLYILVKGNTPESNRDEFFVIDRQNGRLKLEKSLDHETTKWYQFSILARCTLDDYEVVASIDVSIQVKDANDNSPVLESSPYEAFIVENLPGGSRVIQIRASDLDSGANGQVMYSLDQSQ-DADIIESFAINMETGWITTLKELDHEERASYQIKVVASDHGEKVQLSSTAIVGVTVTDVNDSPPRFTAEIYKGTVSEDDPPGGVIAILSTTDADTEEINRQVSYFITGGDALGQFAVENVQSDWRVYVKKPLDREQKDSYLLTVTATDGTFSSKARVEVKVLDANDNSPVCEKTSYSDTIPEDALPGKLVMQVSATDADIRSNAEITYTLFGSGAEKFKLNPDTGELRTLALLDREEQAVYNLLVKATDGG--GRSCQAAIVLTLEDVNDNAPEFTAEPYTITVFENTEPGTPLTRVQATDADTGLNRKISYSLVESADGQFSINERSGIIQLEKHLDRELQAVYTLTLKAVDQGLPRRLTATGTVVVSVLDINDNPPVFEYREYGASVSEDIVIGTEVLQVYAASRDIEANAEITYAIISGNEHGKFSIDSKTGAIFIIESLDYESSHEYYLTVEATDGGTPSLSDVATVNINVTDINDNSPVFSQDTYTTVVSEDAALEQPVITIMADDADGPSNSHIHYSIIEGNQGSPFTIDPVRGEVKVTKPLDRETISGYTLTVQAADNGNPPRVNTTTVNIDVSDVNDNAPLFSRDNYSVIIQENKPVGFSVLKLVVTDKDSSHNGPPFFFTIVSGNDENAFEVNQHGVLLTAATIKRKVKDHYLLHVKVADSGKPQLSSMTHIDIRVIEESIHPPAILPLEIFITAFGEEYSGGVIGKIHATDQDVYDTLMYSLDP------HMDGLFSVSSTGGKLIAHRKLDIGQYLLNVSVTDGKFTTVADITVHIQQVTQEMLNHTVAIRFANLTPEEFVGDYWRNFQRALRNILGVRKNDIQIVSLQP--------------SEPHS-HLDVLLFVERS-----GGTHVSTKQLLHKINSSVTDVEEIIGVRILEVFQKLCAG--LDCPWKFCDEKVSVDENVMSTHSTARLSFVTPRHHRTAVCLCK----DGTCPPVHHGCEDNPCPAGSECVADPREEKYSCVCPGGGFGKCPGSSS---------------ITFTGNSFVKYRLLENENRLEMK----LSMRLRTYSSHAVVMYARG-TDYSILEIHTGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVSLEVEGNYAKLVLDEVHTASGTAPGALKTLNLDNYVFFGGHLRQQGTKHGRGAQVASGFRGCMDSIYLNGQELPLNNKPR-AYAHIEEWVDLSHGCLLT----ATEDCSSSPCQNGGVCNPSPTGGYYCKCSALYVGTFCEVSVNPCSSNPCLYGGTCMVDN-GGFVCQCRGLYTGQRCQLSPYCKDDPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECAGNPCRNGALCENTHGSYHCNCSQEYRGKHCED--ASPNHYVSTPWNIGLAEGIGIIVFIAGIVLLVMVFVLCRKMISRKKKRQAEPEDKR---LGPTTAFLQRPYFDSKLNKNIYSDIPPQVPVRPISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPESMHGHRKAVAVCSVAPNLPPPPPSNSPSDSDSIQKPSWDFDYDAKVVDLDPCLSKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDD--------------------NESLAAPDLSKPRGYHWDTSDWMPS--VPLPDIQEFPNYEAIDEHTPLYSADPNAIDTDYYPGGYDIESDFPPPPEDFPAPDELPPLP--PEFSDQFESIHPPR---DMPAAGSLGSSSRSR----QRFNLNQYLPNFYPADMSEPQKQGAGENSPCREP---YTPYPPGYQRNFEAPTIENMPMSVYASTASCSDVSACCEVESEVMMSDYESGDD--GHFEEVTIPPLDSQ--QHTEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14517-1", "uniprot_id": "FAT1_HUMAN", "id": "Q14517-1", "name": "Protocadherin Fat 1", "aln": "---------------------MGRHLALLLLLLLLFQHFGDSDGSQRLEQTP-------LQFTHLEYNVTVQENSAAKTYVG--HPVKMGVYITHPAWEVRYKIVSGDSENLFKAEEYILGDFCFLRIRTKGGNTAILNREVKDHYTLIVKALEKNTN-----VEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDP-AYAIVTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDKGTPPQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIP----AYSHLRYVFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDRK-------ASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSIANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQLVQYQIEAGNELDFFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAAS---------HKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDS------HSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQKAAWRLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTDTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGN--FDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDED-ARRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNA-RREPLYHVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVSSKRFSAAGEYDILSIKAVDNGRPQKSSTTRLHIEWISK-PKPSLEPISFEES-FFTFTVMESDPVAHMIG-VISVEPPGIPLWFDITG-----------------------GNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTILTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFVGMVTAHSQSSVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVP---LVIRAADADKDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITEGNIGEKFSMDYKTGALTVQNTTQLRSR----YELTVRASDGRFAGLTSVKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITAIGNPINEPLFYHILNPDRRFKISRTSGVLSTTGTPFDREQQEAFDVVVEVT-----EEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLKEHH-EHFQIG-PLGEISLKKQFELDTLNKEYLVTVVAKDGGNPAFSAEVIVPITVMNKAMPVFEKPFYSAEIAESIQVHSPV-VHVQANSPEGLKVFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAEVFVDIIVDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKS-HDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIITLSNLHRHALKPFYSLNLSVSDGVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFYINER-GQIFTLEKLDRETPAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADEGSNADITYAIEADSES--VKENLEINKLSGVITTKESLIGLENEFFTFFVRAVDNGSPSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPIGTEIDLIRAEHSGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSLDQSQ-SVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATDGTFSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGG--GRFCQASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEKAFEVNPQGVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPLEIFITSSGEEYSGGVIGKIHATDQDVYDTLTYSLDP------QMDNLFSVSSTGGKLIAHKKLDIGQYLLNVSVTDGKFTTVADITVHIRQVTQEMLNHTIAIRFANLTPEEFVGDYWRNFQRALRNILGVRRNDIQIVSLQS--------------SEPHP-HLDVLLFVEKP-----GSAQISTKQLLHKINSSVTDIEEIIGVRILNVFQKLCAG--LDCPWKFCDEKVSVDESVMSTHSTARLSFVTPRHHRAAVCLCK----EGRCPPVHHGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQCPGSSS---------------MTLTGNSYVKYRLTENENKLEMK----LTMRLRTYSTHAVVMYARG-TDYSILEIHHGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLDQVHTASGTAPGTLKTLNLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPR-SYAHIEESVDVSPGCFLT----ATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSKPCLYGGTCVVDN-GGFVCQCRGLYTGQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECSGNPCLHGALCENTHGSYHCNCSHEYRGRHCED--AAPNQYVSTPWNIGLAEGIGIVVFVAGIFLLVVVFVLCRKMISRKKKHQAEPKDKH---LGPATAFLQRPYFDSKLNKNIYSDIPPQVPVRPISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPESVHGHRKAVAVCSVAPNLPPPPPSNSPSDSDSIQKPSWDFDYDTKVVDLDPCLSKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDD--------------------------------NGYHWDTSDWMPS--VPLPDIQEFPNYEVIDEQTPLYSADPNAIDTDYYPGGYDIESDFPPPPEDFPAADELPPLP--PEFSNQFESIHPPR---DMPAAGSLGSSSRNR----QRFNLNQYLPNFYPLDMSEPQTKGTGENSTCREP---HAPYPPGYQRHFEAPAVESMPMSVYASTASCSDVSACCEVESEVMMSDYESGDD--GHFEEVTIPPLDSQ--QHTEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PRG7-1", "uniprot_id": "A0A8M9PRG7_DANRE", "id": "A0A8M9PRG7-1", "name": "", "aln": "---------------------MQNHMTSLLVVLLLLCGCTAN---QSQDNAPI------PLFTQSVYNATIYENSAAKTYVE--SPVKMGIYITDPTWEIRYKIVSGDNENLFKAEDYHLGDFSFLRIRTKGGSSAILNREVRDHYILTVKAMEKNSN-----AEARTRVRIQVLDTNDLRPLFSPTAYSISLPENTAIRTSVAKVMATDADIGTNGEYYYSFREWTDMFSVHPTSGVVTLTGKLDYSETKQYELEILAVDRGMKLYGSSGFSSMAKLTVRVDQANEHAPVITAVTLAASETDKDP-TYAVVTVEDNDQGANGEIASLSVVAGDPLQQFKAMRTSPGSKEYQIKAVKQVDWDSQPFGYNLTLQAKDKGNPPQFSSAKVIHVMSPHFKVGPPKFIQAIYRVNVSEFAPLHTPVVMVTAVP----KYPQLKYAFRHRLDKNHFAINPDSGLITTAAPLHADSVNKYELEVVTSDKK-------AVTKVIIDVIDVNNNGPEFKQTSYKASLDENMPTGTSVLTVKATDLDSGENGYVTYSIANVNSQPFVIDYFSGVISSSETLDYELMPRIYTLKVRASDWGSPYRREVETQVTIMLNNLNDNKPLFENVDCDATVPRDHGVGDQITTVSAIDADELQLVRYRIKAGNDLNVFEMNPSSGVLSLKQTLSEGEAAKVSYHSLQIIASDGEHETQPMFLNITVVTA---------HKPVQVKCVDTGVASMLAEKLLQGSKVHTQSEPEDHFQDF------HSVNRVAPQFADTFPSVIEVKEDLPVGARIVHLSASDSDSGFNGKLVYVISGGDAESRFIIDMDSGWLKVFAPLDRETTDHYTLNITVYDLGIPQKSSSRLLDVKILDANDNSPQFLKETYSVEISESSTVGTEVIQVEAKDKDLGDNGVVRYSILADTDQFAIDTETGIVTVKKPLDREVQPVFVLKIAARDQATAEPQLVSTVLLKITLEDVNDNPPKFIPPNYHVRVREDLPIGTVIMWLEAHDPDVGPSSQVRYSLIDSGDGK--FEVDKLSGAVRIVQNLDYEKKQVYSLTAKAKDKGKPISLSSSCHIEVEVVDVNENLYRPLFPSFVDKGFIKEDVPIGTSVMKITAQDED-KGRDGEIRYSIRDGSGLGIFTIDEDTGVIRTQELLDHETVPHYWLTVYATDRGVVPLSSFVEVYIEVQDVNDNAPQTSEPVYYPSVMESSPKDVSIIQIEAFDPDTKSSEKLSYKITSGNPQGFFSINQKTGLVTTTSRKLDREQQDEHILEITVSDQGVPAKSTTVRVIVKVLDENDNSPQFMEKVYKIKLPVREKPEKERAL-KRDPVYRVIASDKDEGPNAEISYSIEEGDEQGKFFIEPKTGMVYSKKLSSAVDYDILTIKAVDNGRPQKSATCRLHIEWIPK-PEPSTVPLVFDEP-FYTFSVMESDTVSHMLG-VISLEPVDTPVWFEITEDIAAKELFYIVQMACDLNCTAEGGNSDSRFEVGKASGTMIVAQALDAEQKSHYNLTVNATDGTRSVSTQVLIKVIDTNNHRPQFSKPKYEVDVSEDTPPETEVLRITATDQDEKNKLTYTLLSSTDPFSLRKFRLDPGTGVLYTAERLDHETMHQHTLTVMVRDQDIPVKRNLVRVIVNVQDTNDNAPWFSGAPYVGRVFESAATGSAVLQVSALDKDKGQNAEIIYSIESGNVANSFAIDPVLGTITVAKELDRNNKNRFELTVKASDKGTPPLSGTAAVDITVTISDNAIPKFAEKEFSAEVSETVLPGAFVSLVTANSQSSVFYQIKDGNVNGAFDINPNSGVVVTHSVLDYETIPSYKLTIQGTNMAGLASNTTLLIHLKDENDNAPVFIQDQFAGMVSESSPVNSVVLTKDNTP---LVIRALDTDRDANSRLVYQIVEPFAHNYFAIDSSTGAIRTISELDYEQRSVFRFSVQVHDMGIPRHFAEKAANVTIEILDVNDCPPQFSQDLYETTVLVPTYKGVEVITVNASDADSGPNSRLFYSIVEGNIGEKFKMDPVTGVITIQNVTQLRSR----YELRVRVSDGRFSKTSLVKINVRENKESTLRFTQESYKAFVPENSSEKKTLAVIAAVGNQVNEPLFYTILNPDKRFTISRTSGVLSSTGTPFDREEQGVFDIVVEVT-----RDDKSPDVAHVLVTVIIEDVNDNPPVFVNLPYQALVQVDADVDHIITKVTAVDADINENAEINYHLQELN-EFVQIS-TDGEISLTKKLDKDSVNTEFIITVVARDGGEPALSSSVEVPILVVNKAMPVFEKAFYSLEIPENIQLLTPI-VHIQANDSEGPRIVYTITEGDPLNQFTINFNTGVIQVVKTLDFETHPAYKLSVRATDSLTGAKAEVFVDIILEDVNDNPPVFHTKLYNASLSEASVIGTSVLEVSATDADTGNNKVLFYQIVEDKDKS-FDYFSIDRDTGTIWTTRMLDHEEKPSHRLLIRAVDGGVPALSSEVMVLIDVMDLNDNTPVFSQNVYEATVSELAPRGHFVTQVQASDADISDSGKLEFSILSGNEGQNFAMDPNTGALVISNHRKPHMESLYNINVSVSDGVFRSSAIVKVNVISANFHNPTFNQVDYVVELLENSPVGTLVAEAQATDDDSGTYGRLTYHIVNDIAKDKFSISEN-GEIFTLESLDRENALEKVIPISLIAKDGGGKVGFCTVNVILTDINDNAPQFRAADYRVNVASDVSRGTTILKIAASDMDEGSNADITYSIETDADN--VEENFEIHQFSGVIVTKESLIGLENQMYTFLVRAKDGGNPTKSSVVPVYVKILAPEVPVPKFIESHYRFAIEEDLSLGSEIDVIQAESDQPVFYSLVKGNTPESNQDEVFVVDPSSGSLKLDKKLDHESTKWYQLTLQAQSEYEGSKVVSAVDISIQVKDVNDNRPLFESNPYEAFVVENLPGGTSVIQVKATDLDSGTNGHVVYNLDPNQETRDIVELFAINSESGWITTLKELDRETRNKYTVSVLATDRGDKVQLMASTRVDVTVVDVNDNPPKFTAEIYKGTVSEDDPPGGVIAILSTTDLDTEENNKQISYFITGGDPLGQFAIEHTQGEWKVSVRKPLDREEKDNYLLNITATDGTFTAKAVVEVKVLDANDNSPICEKSFYMESVPEDSPAGRLILQVSATDADIRSNAQISYELLGPGSEHFSIDSETGELKTLLPLDREEEEVHKMKVRALDGG--GRFCEAEVEITVEDVNDNPPQFTTDPYTFTVFENTEINTPVARLYASDLDTGANAEILYSLLDSADGVFSIEEETGVVRLDRPLDRELQSLYTLRAQATDRGSPRHLSSHTTVSVSILDINDNPPVFERREYTATVAEDIPVGTQVLRIHAASRDTEAGTEITYAIINGNERGAFRVDPQTGGVFVIEPLDYETAHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPVFNQDIYSAVISEDAELGKTVLTVMADDADGPSSNQVRFSIIDGNQGSPFTIDPVRGEVKVARLLDREKTSGYTLTVLASDNGSPARSSSATINVDVSDINDNPPIFSQANYSIIIQENQPIGASVLQLTVSDRDASHNGPPFTFSIIRGNEGDFFRITPQGVLVSAATLSRQTQEFYLLQAQVTDSGRPPLVSTAFVSVRLIEESIYPPSILPLDIFITTATDEYSGGVLGKIHATDQDVYDTLTYSLAPDSSSTSENSGLFSVSPADGKLVARGNLDAGQYVLNITVTDGRFTAAARVNIHVRQATAQALDNSIAVRFSAIAPEEFIGDYWRNFLRALRNIAGVRRGDVQLVSLQP--------------AADASGDLEVLLALERS-----GSPFQPQEVLYRKLNASVGVIEEMTGVRIVRVMKKLCAG--LDCPLSFCQETIALETGAVSAYSTARISFVTPRHMRTAKCLCE----GAECSILSKLCEGSPCPDGMECVEDPTHSKYRCICPEGKQEECSERQS---------------LTFSGNGYARYRLMENENKEEMK----LSLRLRTFSTHATVMYAKG-TDYSILEIVNGRLQYKFDCGSGPGVVSVHSTQVSDGQWHTVSLEVDGNYARLVLDQVHAASGTAPGTLRTLNLDTSMYFGGHVR---PASGSGRLVMNGLRGCLEGIVFNGRELPLSQVRG-AHSVLEELVEAAPGCSLAP---PIQGCTSNPCTNGGTCLALPNGGYFCKCTAAFMGTHCEVTISPCASNPCLYGGTCIPRG-GDFYCQCRGQYSGQRCQLGPYCTDNPCKNSGKCIDSLDGPVCECEPGFQGERCLSDVDECLKNPCGNGGHCQNTYGSFSCNCSNGYSGQHCELRSEIRNEFVSTSWNIGLEEVIGIVVFVASIFFLVLLFVVVRKRICRRSKSKSDDDDKIGISTGTQNSFLHRPYFDAKLNRNIYSDIPPQVPVRPISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPDSVHGHRKTVAVCSVAPNLPPPPPSNSVSDSDSIQKPSWDYDYDAKVVDLDSCLSKKPVEDSACHPYNTRGSMSEVHSLSSFQSESCDDNASLVTVIHLVSSVVDSVEKEESFSAHEHKNPRGYHWDTSDWMPS--VQLPGIQEFPQYEVVEAPPTLYS-DPALLDTDYYPGGYDIESDFPPPPDDFPSHDDLPPPPPVPEYGDRYDTLQPASRGLNSTPSSPGGSSIRHRPPLPQLYSLTQFLPHHHYSSDPEPQTNPTSTSTSSSTEGYRHGGFSLGYRRDFDPPAADNMSLSLYTSTASCSDMSACCE-ESEVMMSDYESGGEEGAQFQRLIIPPLDSQHQQHTEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW71-1", "uniprot_id": "FAT2_DROME", "id": "Q9VW71-1", "name": "Fat-like cadherin-related tumor suppressor homolog", "aln": "MFTMKIKKYVTPVKRKAFTILQWISLLCSLWLIPTVQSKADEKHTATLEYRLENQLQDLYRFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRVGLNAEVKYRIISGDKEKLFKAEEKLVGDFAFLAIRTRTNN-VVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVNDKDTGINGNIGRLEIVDGNPDGTF-LLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIP-IFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKK---TTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVN-FPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGS--PVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDP-SLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQ-GSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVN--------QSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDDNDQLWYNISN-----------------------GNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSIFFNIISGNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDADN---DTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASDGIFSAILIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRILNPTQLFDIGISSGALKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNGELFKLDRKSGELSIKQHVEG--HNRNYELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAESPLGRSLIYTISSES--QSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVS--DGGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGNYTFKFSIAA------DQDHFMISD--SGELILQQTLDREQQESHNLIVVAETSTVP-VFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDT--ENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNG-HPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEK--QEMDFFIVSGDKQAQFQIGKSG---ELFIAKPLDREQLMFYNLSIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQS--KLRFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVP-KLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPLEVTINSFEDDFSGAFIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIGLYKLNVSVSDGKFHVFSIVKINVELVTNDMLKESVVIRFRRISASEFLLSHRKTFMRSIRNIMRCRQKDVILITLQSDYQKASQHAVGNRRARSIDSDLNVVFAVRKQQIIPDSDEFFTSDEIRQTLIDKKNEIENETNLVVEDVLPSTCQSNKNDCVHGECKQILQILKNNVTTTFTDVISFAAPSYIPVNTCVCRPGFDGKHCKETVNACSTDPCSPQRICMPSGSALGYQCVCPKGFSGTYCERKSSKCSNESCDMGLFTAVSFGGKSYAHYKINKVKAKFTLENGFSYSLQIRTVQQTGTLLYASGKVDYNILEIINGAVQYRFDLGSGEGVISVSSINISDGEWHQISLERSLNSAKVMVDNKHVSHGSAPGVNGILNIQSNDIFVGAEVRPHPSIIGYEDIQRGFIGCMANIKIAKESLPLYISGGSTIAALKRFTNVEFKCDPSNVLVRLGICGSQPCANSGICKELDTDVFECACQPRYSGKHCEIDLDPCSSGPCLFGGRCDYHGPNNYSCTCPIHLSGKRCEYGKFCTPNPCKNGGICEEGDGISHCMCR-GYTGPTCEIDVDECENQPCGNGATCINEPGSFRCICPSYLTGASCGDP-LYSNSISTKLKNFSIEHISGIISGVAVVLVIISCVLCCVVLKRSSSSKRRNRLEKDKNKSSYKEANLNSLVDKDNYCKPNVKLSNLEVNQRPISYT-AVPNDNLVLSNRNFVNNLDILRSYGSAGDELENVPFEYQKVNRNKQHVNIN----SCHSTDADNAYKQEWCEQMHLRTFSENKLNNELKRDFGPSVSRFSTGKLIQVEMPNVCHSSSANF------------------------VDYSALANGQYHWDCSDWVRKSHNPLPDITEVPGAEIADSSS-LHSNDSNESKSKKAFFVHREDGDVDPTRDIAALNEDIGSEYLDSEAESCLEPFMLPR-----SSNQPLSRLSSFN-----NIENEDYKSNTVPLPSKVSHSCKVYLRHPDSYLPTMHFPSETDGESSMTEGPISRMEIKTRRTISENSEEAYLFPCTVGEIGSNSNISVR-LCEIEDSELEEFLPQ--QQTNN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :: . : *:: **.*: *** .***. ::. *::*:*:***.*:*****: :***.** ***: .. .:**** :.* : :** : : *:.:.::::*** *** *** ** *:: :**:*. *: :* * ***:* *** ***: :: *::***:* :.* :*: *.. :*: ::* *** : .. :* :*::: :.*.* ** * : *::. :* *.:: *:* * * **:*. *.:* *: * ::: .. : :: . :.: : ****: *:* *.* :*: .* .*. : * * :*...:.* ** : **: :.. . : : .* :* ::*:: : : : * * : *: : ::* :.* . *.* * * :. :::** *: * :.* * *.***.*::*****:* ** **:*:* :.::. **:* * * * * :****** ****:.* :* ::::*** * **. :* ..:.:. :* :: ..**** * ::: *::. **: . * ::*.** **:. * . :.:: : *:: *:** : : : :*: : . : ...* :**** ***.* ..* : :. . * * :. * *:* :* :.::*. :* : :.:.* * *:*****:.:*.*: :* * :* : * *:::. **** :.*.********* * ::: ::* : ::*.*** * : : ..::*. : : : :.*.* * * .. * *:: .: . *::: ** : : :***** * . *:* *:* . * * * .:: : ::*****.* * .* .:****** **:: :** * *:* ..::::** : :.. * :** :**:* **:*:**::.* . * * *.* **:* : : ::***** . * * .** :* :**: * *: **.::*:* * :.:* *** .*.*:*:* :.:: * * : . ** *: .****: * * .:****. :*:**:*:: *** * *.:**** .: * * ::*.:: ::***** ...:.: *.*.*** *:*.*. ***::.**.******:* *****::::*:* * *: *::*.:** *** *:* ::.**:::* . : :.:::* * *.*.* *..::***:.*. :.:* *:.: * : : : : : *** *** *:** * *::* :. *:.. *: . :. . : *.* ..:: ::::: . :*::* ** *. * :.: .*.::::: ** * :. ****:..**** : *:::::*** *:: ***:. *.* :.*: * :::: *.*:**.:** * * :: ** ** **:*. :* : .:::**.* ** * *:*:**. * *** .:::*** * **: * *:. .:* **** ** : :* *:*:*.*:***: *** :**:.. * *** :* *. * :*: .: : * *** * * **:* .* * **:::* ***. :: : *: * : *:** *:*.*.**:.::: .** . :* *** :* :: : :*:*:: :.* ::*****. :: .:::*: * *** * * : :: * :.**:.:.* **. : . *.::. *:* *. : *:**: .:.:* **.:****. : .**** : * * * *** *: .: :*:**:.::::***** * : :.::::**:..* * *.*.***. . : :.*..** .* *.:: ** :: :* *... * * **.*** *: *:*:* . :* : * :: * . **.:: *:.:: .:** ::* : * **** : * *. :**.*.:** **** : : :.**.. . * . : : : * *** *:***:** * *.:* . :* *.*:* * .*.::.* *:: : : .::. *::*:.::.: * :: :**.* **. .. *:.. : : *::::****** **: .: *.:: :.: * ::*:.. * :.*:*:. . ..* *::*** : *: **:* .::.:*:******:*. ***.:.: : *:** * : * ::.* : :*: :::: *** *: * : * : :.:. : * :* * : **:*: * :.:.. * * *.*** * : * *****.* * : * : :* * :*:** :* * * ** . *::.*: **: : : :* ** : :.* . :. :*:******. : : :::.:: *.:.* * * * .:: ** : .:::* * * *..: *.:*.: *. * :.: * : : :*** * *: : : *.***..*.:::**:.* ***.* * .*.: :.: . . :::.: *.* * .*..: : * .::. *:: :**:: :* *. *.. . : : *:*** * *.* * * * ::*: .: :* * :. : *. . *: : :: . .. : :. ::*. :: * .* * *::.**:* : ::: : *. ..: *: *:*:* *** * ::.. *.* :.** :::: *:* *:* **.: * *: . :: : * *: :**** *..**:* : .* ..*:*:*.* : : :.. * :.:.* **..* *. * :* *: * *: * * * *: ::: :**..** .** : .: : ******: * *.: ****.*::** **:.* * ***:* * :. * : *. * ::::.* * *::* :: : * * *::.*.:. ::* *:. **** ::: .:. ** : * : : :*::*:*** * *: * .:* *::: .* :::: * * * * * :* ***: . .. *.*.: :*:::*.: **** :::.* :* * * * :* : ** *.:******** *. *:* ..: *: **:* :::*:* * ..::* * *:.***:* * :*. ** :.: **** :: ::**::* *****.**: * **:.: *:***:*.* *: * :.** : . :: : * * *. .. : :.* *:: . *:*** .* :.*:: ****. * *** : *.*:*.* * .:..:*::: * ***.*:** ***:::***: :* .* : ::* * : * .*: * * **: *.: .* * ::: ..:: :: ::::.:* *.* * * * : : :::**** :** : **:: *.: :::**..:**:**:*** ** * :** . . . **.:* **: * :** * * **::*:**:* . : :.:::. .* : *..::.:** ::..**: .: :.* *::*** *: *: :::**. : .*:*:: :.: .. . . : :.: . :*: .: : *: . * . ** *.: : : . ::: * :**.:* : . *:*. * : *. .**. *: . : *:** * .* ::: *..:.:*:: : : : :: ::::** . ..::** * .**.**** * :**:** *** *::** * ::.**:** ::** . * *::::*: *.: *:***. **::. * * . : *: **: .* : ..*** : : ::. .: * : * *.** *.* * . : * * . . *..**: :.**:* ***:** * . ..: * * :*:**: . :*. :****.* * :. . . * * *: * * *:*** :** :*. * * **: * *. * * * :. *:.: . **: :* :..:: .: .. : : :* . : *: . : : . :* ****** ::*.*. :** .:. * . : : :.: . : * . *: * :*:*. * .* : . :... : .: : .. . : .: :*. . :*.*.: **** ***: . **.* *.* * : . *:* *. .:. : :.*. *. : . ::: . .* . :.: . .. . . . . :: .: .:. . . : . . : . . * :. : :. *: : : *: : . .:: : : .* *:*: ", "identical_positions": 1378, "similar_positions": 1570, "identity": "28.62%" }, { "cls_id": "homologset.agr.RGD:621255", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZ81-1", "uniprot_id": "AGO2_RAT", "id": "Q9QZ81-1", "name": "Protein argonaute-2", "aln": "-----------MYSG---AGPVLASPAPTTSPIPGYAFKPPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGG-------------------------RNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKEYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJG0-1", "uniprot_id": "AGO2_MOUSE", "id": "Q8CJG0-1", "name": "Protein argonaute-2", "aln": "-----------MYSG---AGPVLASPAPTTSPIPGYAFKPPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGG-------------------------RNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKV8-1", "uniprot_id": "AGO2_HUMAN", "id": "Q9UKV8-1", "name": "Protein argonaute-2", "aln": "-----------MYSG---AGPALAPPAPPP-PIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGG-------------------------RNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AKD0-1", "uniprot_id": "A0A8M3AKD0_DANRE", "id": "A0A8M3AKD0-1", "name": "Protein argonaute-2", "aln": "MYPIGAAGATELFQGRPSSGSDVSAPASPP-APQEYVFKPPQRPDFGTMGRTIKLQANFFEMEIPKLEVYHYEIDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVYDGRKNLYTAMPLPIGRDKVELEVTIPGEGKDRSFKVAIKWMSCVSLQALHEALSGRLPNIPFETIQALDVVMRHLPSMRYTPVGRSFFTPSEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTIECTVAQYFKDKYKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQDEISKLMRSANFNTDPYVREFGVMVRDDMTEVNGRVLQAPSILYGGRVRISSAQLSIWLNPCLIWSCLWLFQNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTELLLKAFTDQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFKHLKYTYQGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQVKNVQKTTPQTLSNLCLKINVKLGGVNNILLPQGRPLVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQQHRQDIIQDLATMVRELLIQFYKSTRFKPTRIIYYRDGISEGQFNQVLQHELLAIREACIKLEKDYQPGITFVVVQKRHHTRLFCMDRNERVGKSGNIPAGTTVDTKITHPFEFDFYLCSHAGIQGTSRPSHYHVLWDDNHFTSDELQVLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQIHQDTLRTMYFA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.* :*. ::.**... . *.**** ****** *************:***:::****:**********************************:************************:******* ***:***:*********:*******.:*****************************.*************************************************:*****************************************************************.***:**********::************************************************************:*********.***********:**:*:**:*.*****.******* :*****************************************: **:**:*********************************:*** ** ***********************************:****:****************************** *************************************.*************:******:*********************:****:*****:***:***************:*******:************ *:*********************** ****************************:*:*****:*********************************************************:********:***********", "identical_positions": 785, "similar_positions": 61, "identity": "87.32%" }, { "cls_id": "homologset.agr.RGD:621256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14910-1", "uniprot_id": "LIN7A_HUMAN", "id": "O14910-1", "name": "Protein lin-7 homolog A", "aln": "MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEG---------------------------------------------------LGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JZS0-1", "uniprot_id": "LIN7A_MOUSE", "id": "Q8JZS0-1", "name": "Protein lin-7 homolog A", "aln": "MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEG---------------------------------------------------LGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQPQQNHMS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z250-1", "uniprot_id": "LIN7A_RAT", "id": "Q9Z250-1", "name": "Protein lin-7 homolog A", "aln": "MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEG---------------------------------------------------LGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQ-PQQNHMS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BC73-1", "uniprot_id": "A0A8M2BC73_DANRE", "id": "A0A8M2BC73-1", "name": "Protein lin-7 homolog", "aln": "-------------MATVT-VQPLTLERDVTRAIELLEKLQESGDVPGHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEYQARATAKATVAAFAASEGHSHPRVVELPKTDEG---------------------------------------------------LGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQILMQQQQQ-QNLAAQQNHMSLFQKKKK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMT8-1", "uniprot_id": "Q8IMT8_DROME", "id": "Q8IMT8-1", "name": "Protein lin-7 homolog", "aln": "-------------MADNA--EPLTLSRDVKRSIELLEKLQASGDFPTTKLAALQKVLNSDFMTSVREVYEHVYETVDIQGSHDVRASATAKATVAAFAASEGHAHPRVVELPKTEEGKTRPYELRIEGIPLYHKTNTLIVKVYRPRIYVSIIHLIWKALSIFNFCFSGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLKQAVGSVKLVVRYTPKVLEEMEMRFDKQRNTRRRQ------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : :****.*** *:******** **:.* ** :*:***:*:* *::****::::**: ::*. : :* ****************:**********:** **************************:**********************:********* * .***************** **:* *.:**** ", "identical_positions": 149, "similar_positions": 30, "identity": "51.2%" }, { "cls_id": "homologset.agr.RGD:621257", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LH54-1", "uniprot_id": "A0ABK0LH54_RAT", "id": "A0ABK0LH54-1", "name": "Mitochondrial amidoxime reducing component 2", "aln": "MGSSSSTALARLGLPGQPRSTWLGVAALGLAAVALG--TVAWRRARPRRRRQLQQVGTVSKVWIYPIKSCKGVSVCET----ECTDMGLRCGKVRDRFWMVVKEDGHMITARQEPRLVLVTITLEN-NYLMLEAPGMEPIVLPIKLPSSNK-IQDCRLFGLDIKGRDCGDEVARWFTS-YLKT-QAYRLVQFDTKMKGRTT-KKLYPSESYLQNYEVAYPDCSPIHLISEASLVDLNTRLQKKVKMEYFRP--NIVVSGCEAFEEDTWDELLIGDVEMKRVLS-CPRCVLTTVDPDTGIIDRK-EPLETLKSYRLCDPSVKSLYQSSPLFGMYFSVEKIGSLRVGDPVYRMVD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922Q1-1", "uniprot_id": "MARC2_MOUSE", "id": "Q922Q1-1", "name": "Mitochondrial amidoxime reducing component 2", "aln": "MGSSSSTALARLGLPGQPRSTWLGVAALGLAAVALG--TVAWRRTRPRRRRQLQQVGTVSKVWIYPIKSCKGVSVCET----ECTDMGLRCGKVRDRFWMVVKEDGHMVTARQEPRLVLVSITLEN-NYLTLEAPGMEQIVLPIKLPSSNK-IHNCRLFGLDIKGRDCGDEVAQWFTN-YLKT-QAYRLVQFDTSMKGRTT-KKLYPSESYLQNYEVAYPDCSPVHLISEASLVDLNTRLKKKVKMEYFRP--NIVVSGCEAFEEDTWDELLIGDVEMKRVLS-CPRCVLTTVDPDTGIIDRK-EPLETLKSYRLCDPSVKSIYQSSPLFGMYFSVEKLGSLRVGDPVYRMVD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969Z3-1", "uniprot_id": "MARC2_HUMAN", "id": "Q969Z3-1", "name": "Mitochondrial amidoxime reducing component 2", "aln": "MGASSSSALARLGLPARPWPRWLGVAALGLAAVALG--TVAWRRAWPRRRRRLQQVGTVAKLWIYPVKSCKGVPVSEA----ECTAMGLRSGNLRDRFWLVIKEDGHMVTARQEPRLVLISIIYEN-NCLIFRAPDMDQLVLPSKQPSSNK-LHNCRIFGLDIKGRDCGNEAAKWFTN-FLKT-EAYRLVQFETNMKGRTS-RKLLP--TLDQNFQVAYPDYCPLLIMTDASLVDLNTRMEKKMKMENFRP--NIVVTGCDAFEEDTWDELLIGSVEVKKVMA-CPRCILTTVDPDTGVIDRK-QPLDTLKSYRLCDPSERELYKLSPLFGIYYSVEKIGSLRVGDPVYRMV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58EJ9-1", "uniprot_id": "MARC1_DANRE", "id": "Q58EJ9-1", "name": "Mitochondrial amidoxime-reducing component 1", "aln": "--MDLKEAFATI--FDQNRKVALYAAGTTVAVLGLG--LVFK---YMRREEKLTRVGVVTKLLVHPLKSGKAVSVEAA----ECLRMGLKYGELRDRHWLVITEDGHMVTGRQQPRLVLVSLTCEG-GHVSLNGPQMEELKFPLN-NSSDL-VVDCRVFSVDVQGRDCGDKVSEWLTR-FLEADKPVRLVHYEPDLKPQRP-HEKEP--LFPKDDEVAYPDAAPVMLMTEASVGDLNSRLDKDLSVFQFRP--SIVVSDCEAFTEDTWDHIRIGEVELKRVIG-CGRCLFTTVDPETGVFSRK-EPLETLKTYRMTDPKQK----TSPILGQYYTVRKTGVLHVGEPVYKITY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z803-1", "uniprot_id": "A1Z803_DROME", "id": "A1Z803-1", "name": "", "aln": "--MATGGNNSTFDLSPKT----LAAVGVGLVAVGGASFLLYRHLTRDVVPQKWRRVGTVERIHFFPVKSCAPMDISKPGVEYDCDVLSMSFEGIRDRTLMVVNEKNEMITARVYPLMTQIKSKKVSPSKLVFSAQDMPDLELDFEKLDGPGKDVKTSVWGVSIDVMPCGDRINTWFSQAILKKESGLKLVHYPYPKPVRCTNPRLKSMPFIRQEDSGTFNDATSFMLMNLSSVADLNTRLKNPVDALQFRGNFELKMDVDEPYAEDNWQWVRIGEDAVFRTVAPCTRCIFTNINAKTAERSSEGEPLKTLRSYRLFN-------YSSPALGVHMGLRLPGKVKANDVVYVEDK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * ... :..:. . : .: :**.* :: ..*:** : : . :* :.: :*** :*:.*...*:*.* * :. :. . . : : . * : : : .. . ::.:.:. **:. *:: *: . :**:: : . . . :: . :: * .. ::. :*: ***:*:.: :. ** .: : :.: **.*: : **. : :.:. * **::*.::..*. . : :**.**::**: : ** :* : :. * ::..: ** ", "identical_positions": 54, "similar_positions": 131, "identity": "15.3%" }, { "cls_id": "homologset.agr.RGD:621258", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAB8-1", "uniprot_id": "F1MAB8_RAT", "id": "F1MAB8-1", "name": "Kinesin-like protein KIF11", "aln": "----------------------------------MASQPSSSSKKKEEKGKNIQVVVRCRPFNLAERKANAHSVVECDHA--RKEVSVRTA---GLTDKTSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEVYTWEE----DPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLSPS----------SDVSERLQMFDDPRNK--------------------------------------------------------------------------------------------RGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTID----GEELVKIGKLNLVDLAGSENIGRSG-AVDKRAREAGNINQSLLTLGRVITALVERTPHIPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNIMNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISE---ESFRAMNGKVTVQEEQIAELAEKIGVLEEELSKAAELFTDS-------EKELNQCKSDLQTKTQELETTQKHLQETKLQLVKEEYVSS--ALERTEKKLHETASKLLNTVKETTRDVSGLHSKLDRKRAIDAHNAEAQESFGRSLSS----------LFNNMEELIRDGSEKQKAMLDVHKALFGNLMSSSVSALDTISTTALESLMSIPENVLARVSQISDMILEEQSLAAQSKTVLQGSIDELVTNLFTSLKTIIAPGVVSILNINRQLQHIFRASVTMAEKVEDQKREIDSFLS---ILCNNLHELRENTVSSLVESQKLCG-NLTEDLKTIKETHSQELCQLSS-SWAERFCALEKKYANIQKPLNSIQENTERKSTDIINKTTVHSKKILADSDGLLQELRHFNEEGTQLVEDSVGHCGSLSSNLETVSQEITQRCGTLNTSTVHFSDQWASCLSKRKEELQNLMEFVNGCCEASSSEITEKIRGHRAAIESQHSSFVVQITSDEEKFKAGSLELDKTIKTGLTKLNCFLQQDLKLDIPTGMTPERKNYLYPST-LVRTEPREQLLDQLQKKQPKPLMMLNCSESSKE-TSQDMEEDREVLEQSTEELVSQEPCVHTSADCSSSGGVPFFQHKKPHGKDKENRGLNPVEKG-KVEEASEHSISKSRLPLRASINLC--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P9P6-1", "uniprot_id": "KIF11_MOUSE", "id": "Q6P9P6-1", "name": "Kinesin-like protein KIF11", "aln": "----------------------------------MASQPSS-LKKKEEKGRNIQVVVRCRPFNLAERKANAHSVVECDHA--RKEVSVRTA---GLTDKTSKKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEVYTWEE----DPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLSPS----------SDVSERLQMFDDPRNK--------------------------------------------------------------------------------------------RGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTID----GEELVKIGKLNLVDLAGSENIGRSG-AVDKRAREAGNINQSLLTLGRVITALVERTPHIPYRESKLTRILQDSLGGRTRTSIIATISPASFNLEETLSTLEYAHRAKNIMNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISE---ESFRAMNGKVTVQEEQIVELVEKIAVLEEELSKATELFMDS-------KNELDQCKSDLQTKTQELETTQKHLQETKLQLVKEEYVSS--ALERTEKTLHDTASKLLNTVKETTRAVSGLHSKLDRKRAIDEHNAEAQESFGKNLNS----------LFNNMEELIKDGSAKQKAMLDVHKTLFGNLMSSSVSALDTITTTALESLVSIPENVSARVSQISDMILEEQSLAAQSKSVLQGLIDELVTDLFTSLKTIVAPSVVSILNINKQLQHIFRASSTVAEKVEDQKREIDSFLS---ILCNNLHELRENTVSSLVESQKLCG-DLTEDLKTIKETHSQELCQLSS-SWAERFCALEKKYENIQKPLNSIQENTELRSTDIINKTTVHSKKILAESDGLLQELRHFNQEGTQLVEESVGHCSSLNSNLETVSQEITQKCGTLNTSTVHFSDQWASCLSKRKEELENLMEFVNGCCKASSSEITKKVREQSAAVANQHSSFVAQMTSDEESCKAGSLELDKTIKTGLTKLNCFLKQDLKLDIPTGMTPERKKYLYPTT-LVRTEPREQLLDQLQKKQPP--MMLNSSEASKE-TSQDMDEEREALEQCTEELVSPETTEHPSADCSSSRGLPFFQRKKPHGKDKENRGLNPVEKY-KVEEASDLSISKSRLPLHTSINL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52732-1", "uniprot_id": "KIF11_HUMAN", "id": "P52732-1", "name": "Kinesin-like protein KIF11", "aln": "----------------------------------MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPV--RKEVSVRTG---GLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEE----DPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPS----------SDVSERLQMFDDPRNK--------------------------------------------------------------------------------------------RGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTID----GEELVKIGKLNLVDLAGSENIGRSG-AVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISE---ENFRVMSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMDN-------KNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITS--ALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNS----------LFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLS---ILCNNLHELQENTICSLVESQKQCG-NLTEDLKTIKQTHSQELCKLMN-LWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNETIKIGLTKLNCFLEQDLKLDIPTGTTPQRKSYLYPST-LVRTEPREHLLDQLKRKQPELLMMLNCSENNKEETIPDVDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHKKSHGKDKENRGINTLERS-KVEETTEHLVTKSRLPLRAQINL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P46863-1", "uniprot_id": "KL61_DROME", "id": "P46863-1", "name": "Kinesin-like protein Klp61F", "aln": "---------------------------------MDISGGNTSRQPQKKSNQNIQVYVRVRPLNSRERCIRSAEVVDVVGP--REVVTRHT------LDSKLTKKFTFDRSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWED----DSDIGIIPRALSHLFDELRMMEVEYTMRISYLELYNEELCDLLS------------TDDTTKIRIFDDSTKK--------------------------------------------------------------------------------------------GSVIIQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIE----GEDMLKIGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVDRAPHVPYRESKLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKEYTEEIDKLKRDLMAARDKNGIYLAE---ETYGEITLKLESQNRELNEKMLLLKALKDELQNKEKIFSEVSMSLVEKTQELKKTEENLLNTKGTLLLTKKVLTKTKRRYKEKKELVA--SHMKTEQVLTTQAQEILAAADLATDDTHQLHGTIERRRELDEKIRRSCDQFKDRMQDNLEMIGGSLNLYQDQQAALKEQLSQEMVNSSYVSQRLALNSSKSIEMLKEMCAQSLQDQTNLHNKLIGEVMKISDQHS--QAFVAKLMEQMQQQQLLMSKEIQTNLQVIEENNQRHKAMLDSMQEKFATIIDSSLQSVEEHAKQMHKKLE---QLG-AMSLPDAEELQNLQEELANER-ALAQQEDALLESMMMQMEQIKN-LRSKNSISMSVHLNKMEE----SRLTRNHRIDDIKSGIQDYQKLGIEASQSAQAELTSQMEAGMLCLDQGVANCSMLQVHMKNLNQKYEKETNENVGSVRVHHNQVEIICQESKQQLEAVQEKTEVNLEQMVDARQQLITEDRQRFIGHATVATDLVQESNRQFSEHAEHQRQQLQICEQELVRFQQSELKTYAPTGTTPSKRDFVYPRT-LVATSPHQEIVRRYR-------QELDWSDLDTTATIDECSEGEHDVSMHSVQELSETETIMNSTPIEPVDGVTVKRGCGTTRNSNSNALKPPVATGGKRSSSLSRSLTPSKTSPRGSPAFVRHNKENVA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28742-1", "uniprot_id": "KIP1_YEAST", "id": "P28742-1", "name": "Kinesin-like protein KIP1", "aln": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGS---HQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAV---NDPKRQIRIFDNNNNN--------------------------------------------------------------------------------------------SSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSG-AENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQ----SEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNN---YNSKCSEVIKGVTEELTR-------------NVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQS------HQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFN---SLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P27895-1", "uniprot_id": "CIN8_YEAST", "id": "P27895-1", "name": "Kinesin-like protein CIN8", "aln": "----------------MPAENQNTGQDRSSNSISKNGNSQVGCHTVPNEELNITVAVRCRGRNEREISMKSSVVVNVPDITGSKEISINTTGDTGITAQMNAKRYTVDKVFGPGASQDLIFDEVAGPLFQDFIKGYNCTVLVYGMTSTGKTYTMTGDEKLYNGELSDA-------AGIIPRVLLKLFDTLELQQNDYVVKCSFIELYNEELKDLLDSNSNGSSNTGFDGQFMKKLRIFDSSTANNTTSNSASSSRSNSRNSSPRSLNDLTPKAALLRKRLRTKSLPNTIKQQYQQQQAVNSRNNSSSNSGSTTNNASSNTNTNNGQRSSMAPNDQTNGIYIQNLQEFHITNAMEGLNLLQKGLKHRQVASTKMNDFSSRSHTIFTITLYKKH--------QDELFRISKMNLVDLAGSENINRSG-ALNQRAKEAGSINQSLLTLGRVINALVDKSGHIPFRESKLTRLLQDSLGGNTKTALIATISPAKVTSEETCSTLEYASKAKNIKNKPQLGSFIMKDILVKNITMELAKIKSDLLSTKSKEGIYMSQ---DHYKNLNSDLESYKNEVQECKREIESLTSKNALLVKDKLKS-----------KETIQSQNCQIESLKTTIDHLRAQLDKQHKTEIEIS--DFNNKLQKLTEVMQMALHDYKKRELDLN-----------------------------------------QKFEMHITKEIKKLKSTLFLQLNTMQQESILQETNIQPNLDMIKNEVLTLMR-----------------TMQEKAELMYKDCVKKILNESPKFFNVVIEKIDIIRVDFQKFYKNIAENLSDISEENNNMKQYLKNHFF-----KNNHQELLNRHVDSTYENIEKRTNEFVENFKKVLNDHLDE------------------------------------NKKLIMQNLTTATSAVIDQEMDLFEPKRVKWENSFDLIND-----------CDSMNNEFYNSMAATLSQIKSTVDTSSNSMNESISVMKGQVEESENAISLLKN--NTKFNDQFEQLINKHNMLKDNIKNSITSTHSHITNVDDIYNTIENIMKNYG--------------------------------------------------NKENATKDEMIENILKEIPNLSKKMPLRLSNINSNSVQSVISPKKHAIEDENKSSENVDNEGSRKMLKIE----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . ** * ** * * * : ::. : : . . * : .* **. :.* :: .. :.:.: *****::.** *.****.** *: . *****.* .:*. * :: :: * :*:***:* ***. : ::::**. : .: ::.::*: : . : ::* :* :* .*:* * *****::*::. . .::.:*.*:**********:.::* . *.:*: **:*********.***::: *:*:*******:**:**** *:*.:******. *** ****** :**.* *.*::.. : *. :*: *: ::: ** ::.*:*::::: : : . : : :: : : . .: . .. : . : . : . : . * . . : . : :. . . . : : : : .. . :: : :: :: .. : : :. : . : : :: . : : . . . . . : .. .:. : . : : . . . . : . . . : : . : . .... ", "identical_positions": 134, "similar_positions": 219, "identity": "10.77%" }, { "cls_id": "homologset.agr.RGD:621259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35492-1", "uniprot_id": "CLK3_MOUSE", "id": "O35492-1", "name": "Dual specificity protein kinase CLK3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MHHCKRYRSPEPD--------PYLSYR------------------------------WKRRRSYSR--------------------EHEGRLRYPSRREPP---PRRS---RSRSHDRIPYQRR---------------------YREHRDSDTYRCEERSP--------SFG-----EDCYGSSRSRHRR-----------RSRERAPYRTRKHAHHCHKRRTRS------------------------CSSASSRS-------------QQSSKRSSRS------------------------------------VEDDKEGHLVCRIGDWLQ--ERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNS-------------EFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIP-----SHMIHRTRKQKYFYKG---------------GLVWDENSSDG---------RYVKENCKPLKSYMLQDSLE-------------------------------------------------HVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERS-------FHSSRNPSR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63117-1", "uniprot_id": "CLK3_RAT", "id": "Q63117-1", "name": "Dual specificity protein kinase CLK3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MHHCKRYRSPEPD--------PYLSYR------------------------------WKRRRSYSR--------------------EHEGRLRYPSRREPP---PRRS---RSRSHDRIPYQRR---------------------YREHRDSDTYRCEERSP--------SFG-----EDCYGSSRSRHRR-----------RSRERGPYRTRKHAHHCHKRRTRS------------------------CSSASSRS-------------QQSSKRSSRS------------------------------------VEDDKEGHLVCRIGDWLQ--ERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNS-------------EFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIP-----SHMIHRTRKQKYFYKG---------------GLVWDENSSDG---------RYVKENCKPLKSYMLQDSLE-------------------------------------------------HVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERS-------FHSSRNPSR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49761-1", "uniprot_id": "CLK3_HUMAN", "id": "P49761-1", "name": "Dual specificity protein kinase CLK3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MHHCKRYRSPEPD--------PYLSYR------------------------------WKRRRSYSR--------------------EHEGRLRYPSRREPP---PRRS---RSRSHDRLPYQRR---------------------YRERRDSDTYRCEERSP--------SFG-----EDYYGPSRSRHRR-----------RSRERGPYRTRKHAHHCHKRRTRS------------------------CSSASSRS-------------QQSSKRSSRS------------------------------------VEDDKEGHLVCRIGDWLQ--ERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNS-------------EFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIP-----SHMIHRTRKQKYFYKG---------------GLVWDENSSDG---------RYVKENCKPLKSYMLQDSLE-------------------------------------------------HVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERS-------FHTSRNPSR--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49762-1", "uniprot_id": "DOA_DROME", "id": "P49762-1", "name": "Serine/threonine-protein kinase Doa", "aln": "MVAANLEVPTSSSSSAATKRQKDVDNKLEKCLNDMLKLKTSSNNNSTSNSNNNAIMSHSLTGEHKDPKTALEGPTSSSSSSSSKYIGESQIPVPVQLYDPQKPLLQQQQQQQRICYPIGKSNSTSQLPMGGYQRLLQHQQQQHHQQQQQQHQEQQQYPQHKRPFLNWNSFACSAMNGASDPFMQQQHMPAHQQQQHLPHKLQQSYSSSHVPKQAPKSGLAMFLQKNTNKENKFGQPMQQQPPGMMPQMYGYQAPQQQSKIGYPRTGAPLTHSASFSSAQRPTALQFHQQHQQQQHLQQQQQHPQQQQHQHSSFGVGMMSRNYYNMPKQPERKPLQTFDPYAYPKPNQMQPVKYQQQQQHPHTQFQNASAGGGGGGAAGLQYDPNTNTQLFYASPASSSSNKQPQQPQQQQQQQQSQLQQSNSVIFNHSGQQHQPHQQQQNEMSKSALGLHFIETAKPVIQDDADGHLIYHTGDILH--HRYKIMATLGEGTFGRVVKVKDMER-DYCMALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDS-------------DYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARNHTLYSKTKTKYFYHG---------------KLDWDEKSSAG---------RYVRDHCKPLFLCQLSDSED-------------------------------------------------HCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHRVGEVSNKQPLSSGSSSRERSHSLSR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32350-1", "uniprot_id": "KNS1_YEAST", "id": "P32350-1", "name": "Dual specificity protein kinase KNS1", "aln": "-MSQNIQIGTRKRSRANMNNSTTTG----------------PANNTSSNKTFLDNFEETRTNKLLDEMFARQNSFLTDNLRNSLDLNQADNPLRPRQHQHQLFLDNENAIELDEEPRIINTTINNSNNHNSSRVDEDADDDIIFIKEQPIQFSSPLILPSSSSINNNN-------------------------------NIVTSNNPG------------------CGTAATSNSTYITTPKKFKKQRTISLPQLPLSKLSYQSN-------------------YFNVPDQTNAIVPRVTQTENELLHLTGSCAKTLEGNKAVNLTIAHSTS------------PFSNPPAQIASLPQSNLKKQIGSS-----------------------LRKFTSNG-------------SSESASSNKSN-----------------------------------FKTDKDGHYVYQENDIFGSGGRFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIIDKMFYKSKHKLGNSPSDLNSTVIKHFDRKTLSLQWPEKNKRGDTITTEKSMKRVLQSCDRLDIYISKVLKQDYGDSLSINWNLPPEKNWSLINSKLAWKRQTHSSSSSTTDELDKETFLFWYWFIDLLRKMFEFDPTKRITAKDALDHEWFN-LGILDDG--------IATYNNTQG-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. . . . . : * . . * : .:: * : . : * . .. . . . . * : . : .: : :* . .... ...* .: * :** : : .* : *: : **:****:*:: * :*:*:*: * :*****: *:. *:.* ::* . .. *: : : *:::.*:*:. :: * . ::*: .*. :* ::: :* ** :: ***: : **********: :. . . .. . : : :**..::: ***** *.:*:*..:::*****.**::* ***: ***:***.*:*.* * :*: *:* **:.**::* * .: :: . : . * * *:.. * : * : *. * . : ::.*:::*:*::*:.*** :** * :* * . :: . :: ", "identical_positions": 116, "similar_positions": 167, "identity": "12.6%" }, { "cls_id": "homologset.agr.RGD:621260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35763-1", "uniprot_id": "MOES_RAT", "id": "O35763-1", "name": "Moesin", "aln": "-MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKAFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLASEMAELTARVSQLEMARKKKESEAEECHQKAQMVQED---LEKTRAELKTAMSTPHVAEPAE--NEHDE---QDENGAEASAELRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTTNDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26041-1", "uniprot_id": "MOES_MOUSE", "id": "P26041-1", "name": "Moesin", "aln": "-MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKAFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLENEKKKRELAEKEKEKIEREKEELMEKLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLASEMAELTARISQLEMARKKKESEAVEWQQKAQMVQED---LEKTRAELKTAMSTPHVAEPAE--NEHDE---QDENGAEASAELRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26038-1", "uniprot_id": "MOES_HUMAN", "id": "P26038-1", "name": "Moesin", "aln": "-MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQED---LEKTRAELKTAMSTPHVAEPAE--NEQDE---QDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66I42-1", "uniprot_id": "MOESA_DANRE", "id": "Q66I42-1", "name": "Moesin a", "aln": "-MPKTISVRVTTMDAELEFAIQPSTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQEATQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQAKYADYNKDAHTPGYLSNEKLLPQRVLEQHKLNKEQWEERIQVWHEEHKGMLREDSMMEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDKMTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAQRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAKEEKNHKKMERALLEDERKKREQAEKEKEKIEKEKEELMERLRVIEEQTRKAQQELEEQTRKALELEQERKRAQEEAERLERERRLAEEAKSALLQQSESQMKNQEHLATELAELTSKISLLEDAKKKKEDEALEWQTKATMVQED---LEKTKEELKNKVMSSHVTEPVHGENDNDE---GDESSAEASAELTSAAAYKDRSEEERMTEAEKNERVQKHLLALTSELANARDETKKTQNDIIHAENVRAGRDKYKTLRQIRSGNTKQRIDEFECM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P46150-1", "uniprot_id": "MOEH_DROME", "id": "P46150-1", "name": "Moesin/ezrin/radixin homolog 1", "aln": "MSPKALNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKVMNQDVKKENPLQFRFRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNKTTHTAGFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRVRINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQE-------REKLQLALAARERAEKKQQEYEDRLKQMQEDMERSQRDLLEAQDMIRRLEEQLKQLQAAKDELELRQKELQAMLQRLEEAKNMEAVEKLKLEEEIMAKQMEVQRIQDEVNAKDEETKRLQDEVEDARRKQVIAAEAAAALLAASTTPQHHHVAEDENENEEELTNGDAGGDVSRDLDTDEHIKDPIED-RRTLAERNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **::.***************..************************** *:*. ***:** *** ***:**.** *:**********:*****: * ***:****:.**.*:*******:*********:::.*.** .*..*:*:.::******::***:.*::**: * .* :**:.*****:::*****************.*:****::***************:*::****************.:***:***********:*:* *:**************************:********:***: *: * ::* : * :*: *::::* ::*: ::*: .::*::* * .**:: *: * :.* .:: : . * : .. : : :* *: .:. :: : *:.*: . : :. .:.. :: * :.: . .. *:::* .: ..:.* :* : ** *: * * **:***::.:* **..:**::***:*:* ** ** **:* *********:**.****:*:*:** *", "identical_positions": 312, "similar_positions": 156, "identity": "53.24%" }, { "cls_id": "homologset.agr.RGD:621261", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VB91-1", "uniprot_id": "Q9VB91_DROME", "id": "Q9VB91-1", "name": "Lipase domain-containing protein", "aln": "--------------------MRVFIALAALLATVSALPIEE-----------------------RVNGENGWYVPQ------------------IDGSFEWMDKQDAEELLN---RNSLIETRS--N----DVSFYLYTKHNPTVGKEIRAD-----------ASS-IEDSHFDKNQGTRFVIHGWNGR-YTDGMNVK-ITRAWLS------KGD------YNVIVVNWDRAQS-VDYISSVRAVPGAGAKVGEMIEYLHEHHHLSMESLEVIGHSLGAHVAGYAGKQVGGKRVHT--IVGLDPAMPLFA-YDKPDKRLSTEDAFYVESIQTNGGEKGFLKP-IGKGTFYPNGGR-NQPGCG--------SDIGGTCAHGRSVTYYVEAVT--EDN-FGTIKCHDYQAALANECGSTYSGVRMGAVTNAYMVDG-----------DFYVPVNGQAPFGKIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB90-1", "uniprot_id": "Q9VB90_DROME", "id": "Q9VB90-1", "name": "Lipase domain-containing protein", "aln": "--------------------MKVFFVLAALLAAVSALPIEE-----------------------RVNGENGWFIPK------------------LDGSFEWMDMQDAEDLLA---NGAQMEGRISTN----AVNFYVYTKSNPTDGKEIKAK-----------SGS-VEDSHFNKDHGTRFVIHGWTQR-YSDDMNTR-ITKAWLS------KGD------YNVIVVDWARARS-VDYASSVLAVPGAGGKVGEMIKYLHDHHGLDYDSLEVIGHSLGAHVAGYAGKTVGDKRVHT--IVGLDPALPLFS-YDKPAKRLSTDDAHYVESIQTNGGKLGFLKP-IGKGAFYPNGGK-SQPGCG--------LDATGSCSHARSVLYYAEAVT--EDN-FGSIKCHDYEDAVAKNCGSTYSSVRMGAITNAYMVEG-----------DFYVPVNSEAPFGKIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB92-1", "uniprot_id": "Q9VB92_DROME", "id": "Q9VB92-1", "name": "Lipase domain-containing protein", "aln": "--------------------MRELFFLAALLVAGNALPIEE-----------------------RINGENGWFVPQ------------------EDGTFQWMDKKDAKELLE---NISPLEFRS--N----EVSFYLYTKQNPTEGQEITAD-----------ASS-IVASHFNKDHGTRFVIHGWKGK-YTDSMNVD-ITKAWLS------KGD------FNVIVVNWARSQS-VDYAMSVRAVPGAGTKVGEMIQYMHENHDMSLETLEVIGHSLGAHVAGYAGKQVGQKRVHT--IVGLDPALPLFS-YDNPDKRLSSEDAFYVESIQTNGGVKGFVKP-IGKAAFYVSGGR-KQPGCG--------VDLAGTCSHARSVIYYAEAIT--ENS-FGAIQCQDYQAALDNECGSSFSSVRMAEDTNAYNVEG-----------HFYVPVNSEAPFGQTE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB89-1", "uniprot_id": "Q9VB89_DROME", "id": "Q9VB89-1", "name": "Lipase domain-containing protein", "aln": "--------------------MKTFLILAFFALAASAIPIKES---------------------ERVHGENGWYVPQ------------------EDGTSEWVDMDVAEQWME---AQELLESRGLTTV---PVKFYLYTSSNPTKGKKITAS-----------TKS-IDASSFNSAHPTRFVIHGWTQS-YTASMNKD-IRSAWLS------RGD------YNVIVVDWARARS-VDYATSVLAVAATGKKVAKMINFLKDNHGLNLNDLYVIGHSLGAHVAGYAGKNT-DGQVHT--IIGLDPALPLFS-YNKPNKRLNSDDAWYVESIQTNGGTLGFLKP-IGKGAFYPNGGK-TQPGCG--------LDLTGACSHGRSTTYYAEAVS--EDN-FGTMKCGDYEEAVSKECGSTYSSVRMGADTNAYMVEG-----------DYYVPVNSKAPFGMIN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB88-1", "uniprot_id": "Q9VB88_DROME", "id": "Q9VB88-1", "name": "Lipase domain-containing protein", "aln": "--------------------MKTFLILAIFALAASAYALEES---------------------ERVNGENGWYVPQ------------------QDGSFEWVDMDVAEEWME---AQEKLEGRGLTTV---PVNFYLFTPKNPSSSKHIYAT-----------TKS-ISKSNFNPAHPTRFVIHGWTQS-YLNSMNSD-IRKAFLS------KGD------YNVIVVDWARARS-VDYATSVMAVAATGKKVAKMINFLKDNHGLNLNDVYVIGHSLGAHVAGYAGKNT-DGQVHT--IIGLDPALPLFS-YNKPNKRLNSDDAWYVESIQTNGGTLGFLKP-IGKGAFYPNGGK-TQPGCP--------LDVTGACSHGRSTTYYAEAVS--EDN-FGTMKCGDYEEAVAKECGSTYSSVRMGADTNAYMVEG-----------DFYVPVNSKAPFGMIN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB93-1", "uniprot_id": "Q9VB93_DROME", "id": "Q9VB93-1", "name": "Lipase domain-containing protein", "aln": "-------------------MMKLFLALAFCVLAANAVEV-------------------------RVNGENGWYVPQ------------------ADGTMEWMDREFAEAYLE---TKNRMEGRNVLN----PVTFYLYTNSNRNSPQEIKAT-----------SAS-ISGSHFNPNHPTRFTIHGWSSS-KDEFINYG-VRDAWFT------HGD------MNMIAVDWGRARS-VDYASSVLAVPGVGEQVATLINFMRSNHGLNLDNTMVIGHSLGAHVSGYAGKNVKNGQLHT--IIGLDPALPLFS-YDSPNKRLSSTDAYYVESIQTNGGTLGFLKP-IGKGAFYPNGGK-SQPGCG--------VDLTGSCAHSRSVIYYAESVT--ENN-FPTMRCGDYEEAVAKECGSSYSSVRMGATTNAYMVAG-----------DYYVPVRSDAPYGMGN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VB94-1", "uniprot_id": "Q9VB94_DROME", "id": "Q9VB94-1", "name": "Lipase domain-containing protein", "aln": "--------------------MRLCLLVLGCVIAASAWPVDQLS--------------------VRDHGINGWFVPQ------------------REGGLRWIGKAEAERQLEYYEAQEALEGRLSTN----TVNFYLYTLQNPSTGQQIKAT-----------QDS-IDGSFFNPQNPTRITIHGWNSN-YKDGVNTR-VADAWFQ------YGD------YNMIAVDWLRGRS-LEYASSVAGAPGAGKKVAALVDFLVEGYGMSLDTLEIVGFSLGAHVAGHTAKQVNSGKVGK--VVGLDPASPLIS-YSNTEKRLSSDDALYVESIQTNGAILGFGQP-IGKASFYMNGGR-SQPGCG--------IDITGSCSHTKAVLYYVEALL--WNN-FPSIKCESSVDANKNNCGNTYSSVFMGASINFFVAEG-----------IFYVPVNKESPYGLGELNSGGEATTGTPEITSTTVDGEDESTTEVSTSTTTDKPEESTTEEPEEDSTTNGKPEESSTTTEQPEDSTTTTEEPIDSTTEAPEDESTTSSPTDGGEQSTTEEPETTTEKPEETSTSPIDTEDSTTKEPEDVSTTPKESEESTTSSPEDDDTTSAPGEDDDTTAAPGGDEEETTTEDPEETTTSPSDADDSTTEEPEEDTTTTKKPVEPSTTTEEPEDSTTEVPEESTTEEPDKETSTTNAEPEVTTTVEPDVDSTVDPEGDQSTREDLEDVSTTAVPTKLPSTTGVPPEVPITTLAPEVPSTSPPQDGNTKNIFIFNVFLVNVKIENKS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9P0-1", "uniprot_id": "Q9V9P0_DROME", "id": "Q9V9P0-1", "name": "Lipase domain-containing protein", "aln": "---------------MRTHLFALCLSMATIGIPKANGVMDDYDAEMGEFMNALPNLDDTPYGLGQRSDISTEPEEDDILASLDDEYEEAKHCVWNTCDKDLSESRGIGKFLDLPFIKKIASNLNPFGSKKLRMHFYLFKREFPECGREVDFS-----------IERKWRHCGFNASLPTRLMIHGWMSQ-SRGSFNRD-VKNAYLK------KGE------YNVIVVDWSASSANINYFSVVKLIETFGAELAQFIRNLNRQFGADFDSMYLIGHSLGAQIAGSAGKRLKPVKVNT--IFALDPAGPKFR-HRGTEFRIDPSDAKYVESMHTSAN-FGFRRP-TGSATFYPNYGA-YQHSC-----------YYLGCSHIRSYQMFAESIN--SPLGFWGTPCIR-DNGRWQCDYSQRQSIQMAGEP-SIHKEG-----------IFYVKTSSSDPFALGKQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VQ96-1", "uniprot_id": "Q9VQ96_DROME", "id": "Q9VQ96-1", "name": "Lipase domain-containing protein", "aln": "---------------MISQLGRISI-MSAVLLAFAAIVFAS-------------------------SSEKTELDPN------------------ATCNYTLVKKKTLG--VDPSFWKKFFKHLIPFTSSRGKMQFILFKRDFADCGRELFVG-----------DVENLRNSGFDARHQTRIVIHGWMSQ-SKGSHIRK-VKNAYLSLTDPGPNGEPAPYEDFNVIVCDWSKTSTNVNYYEVAKTVEDMGALLAELVRYLNQEANMHYDDVYVIGHSLGAQIAGSAGKQIMPYRFNT--IYALDPAGPQFR-EKSDEYRIDASDASYVESIQTSVS-FGFEQP-VGHATFYPNYGK-NQKKC-----------YVYGCSHKRSHDYFIESLT--SPAGFWGPRCERHDDGTWLLLMSDGE-FRMGGEP-SIPKNG-----------TFYVKTYSKPPYAMGHRWQTEPPPREDDIENSTEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P97535-1", "uniprot_id": "PLA1A_RAT", "id": "P97535-1", "name": "Phospholipase A1 member A", "aln": "--------------MCPGLWGTCFWLWGSLLWLSIG----------------------------------------------------------RSGNVPPTTQPKCTDFQS----ANLLRG------TNLKVQFLLFTPSDPGCGQLVEED-------------SDIRNSEFNASLGTKLIIHGFRALGTKPSWINK-FIRALLR------AAD------ANVIAVDWVYGST-GMYFSAVENVVKLSLEISRFLSKLLELG-VSESSIHIIGVSLGAHVGGMVGHFY-KGQLGR--ITGLDPAGPEYT-RASLEERLDSGDALFVEAIHTDTDNLGIRIP-VGHVDYFVNGGQ-DQPGCP-AFIHA--GYSYLICDHMRAVHLYISALE--NTCPLMAFPCASYKAFLAGDCLDCFNPFLLSCPRIGLVERGGVKIEPLPKEVRVYLQTTSSAPYCVHHSLVEFNLKEKRKKDTSIEVTFLGN-NVTSSVKITIPKDHLEGRGIIAHQNPHCQINQVKLKFHISSRVWRKDRTPIVGTFCTAPLPVNDSKKTVCIPEPVRLQVSMAVLRDLKMACV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VI78-1", "uniprot_id": "PLA1A_MOUSE", "id": "Q8VI78-1", "name": "Phospholipase A1 member A", "aln": "--------------MRPGLWETCFWLWGPLLWLSIG----------------------------------------------------------SSGNVPPTTQPKCTDFQS----ANLLRG------TNLKVQFLLFTPSDPSCGQLVEEG-------------SDIRSSEFNASLGTKVIIHGFRALGTKPSWIDK-FISAVLR------AAD------ANVIAVDWVYGST-GVYYSAVENVVKLSLEISRFLSKLLELG-VSESSIHIIGVSLGAHVGGMVGHFY-KGQLGQ--ITGLDPAGPEYT-RASLEERLDAGDALFVEAIHTDTDNLGIRIP-VGHVDYFVNGGQ-DQPGCP-AFFHA--GYNYLICDHMRAVHLYISALE--NTCPLMAFPCASYKAFLAGDCLDCFNPFLLSCPRIGLVERGGVMIEPLPKEVKVYLLTTSSAPYCVHHSLVEFYLKEKRKKDTSIEVTFLSN-NVTSSVKITIPKQQLEGRGVMAHPNPQCQINQVKLKFQVSSRVWRKDRTPVVGTFCTAPLPVNDSKKTVCIPEPVRLQAGVPAFQDLKIACV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53H76-1", "uniprot_id": "PLA1A_HUMAN", "id": "Q53H76-1", "name": "Phospholipase A1 member A", "aln": "--------------MPPGPWESCFWVGGLILWLSVG----------------------------------------------------------SSGDAPPTPQPKCADFQS----ANLFEG------TDLKVQFLLFVPSNPSCGQLVEGS-------------SDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDT-FIRTLLR------ATN------ANVIAVDWIYGST-GVYFSAVKNVIKLSLEISLFLNKLLVLG-VSESSIHIIGVSLGAHVGGMVGQLF-GGQLGQ--ITGLDPAGPEYT-RASVEERLDAGDALFVEAIHTDTDNLGIRIP-VGHVDYFVNGGQ-DQPGCP-TFFYA--GYSYLICDHMRAVHLYISALE--NSCPLMAFPCASYKAFLAGRCLDCFNPFLLSCPRIGLVEQGGVKIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVTFLSS-NITSSSKITIPKQQRYGKGIIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFCTALLPVNDREKMVCLPEPVNLQASVTVSCDLKIACV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYZ4-1", "uniprot_id": "PLA1A_DANRE", "id": "Q6NYZ4-1", "name": "Phospholipase A1 member A", "aln": "---------------MAWKWIKAFVYLSVCVTSALG----------------------------------------------------------DDEEASAS---KCADFNN----TTWLEYRQA---TKLQVQYLLLTRKNANCASLFTQDC---------LNHTQKHTAYFNSSLPTKVIVHGYRALGSKPSWVSG-LAQALLR------EED------VNVLVVDWVYGAS-FAYNLVVENYKEVAVQISVLINQLTKYG-STLESFHFIGVSLGAHVSGFVGTLF-HGKLGR--ITGLDPAGPMFK-SADPFDRLDSSDALFVEAIHTDSDYFGISIP-VGHVDFFLNGGM-DQAGCARSRFAS--MYGYVICDHMRALHVYMSALN--GSCPLIGFPCSGYEEFLAGKCITCDDPFNGTCPQIGLLKNSGITATPLPNQEKVYLLTTASGPFCAHHILVELNVS-RLDKTAEVQLILKSIGHPETELNLKLYTDETRYKTVAAHPEQLCKIDSMQLIN-TGGRFYRQG-DIHFEYICISEIPQTRGMDPLCVKN-IHIGRGVPWSHDFVQVC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAL5-1", "uniprot_id": "A1ZAL5_DROME", "id": "A1ZAL5-1", "name": "Lipase domain-containing protein", "aln": "---------------MVLTAASTLCNVFTFLLAGSPIFYS------------------------------------------------------AAPRGSCSTCCAIKERED--------------------IKFMLYTSRNRNSAQLLHLS-----------DDARLAQSNFNFNYPLAIYLHGFSESATGERQSSQELKDAFLR------RGN------YNVILIDWSAMTAVPWYSNAVENLPVSGRYLARFLRFLVDKG-YPAKYIHLIGFSLGAEVAGFAGKQLQEWGIKLPRITALDPALPLFE-GNSSNRRLSPSDARFVDVIHTDGGLLGNPAP-MGHADFYPNGGRPLQPGCAKQNIANNWLGIIVGCSHQRAWEYFVESIA--QPRGFPAQRCEPSDMFG--ICREPGGGPAFMGMGADPRIRG-----------KFYLDTNDAKPFGRNSRARAIVSLAPRLPIAYKLPPNATRQPSVSRWANGQKEQDNEDEDNNALSNNIDRFSLT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0E8T1-1", "uniprot_id": "Q0E8T1_DROME", "id": "Q0E8T1-1", "name": "Lipase domain-containing protein", "aln": "------------------MMNNILVLIGFSSVMLVAG---------------------------------------------------------LDDMNCFSLQNEICPNAN--------------------ISFWLYTKENQEGTKLSVFE---------------LNRFEFYHHKPLKVLIHGFNGH--RDFSPNTQLRPLFLT-------QD------YNLISLDYPKLAYEPCYTEAVHNAKYVARCTAQLLRVLLESGLVKIEDLHLIGLGLGAHVAGFIGQFLPEHKLEH--ITALDPAKPFYM-VKDPALKLDPTDAKFVDVVHTDVTMLGLLDA-VGHVDFYLNMGV-SQPNCG-----PINKMETHFCYHNRAADYYAESIS--SPSGFYGFYCPNFKSFAKGICIPDKNIELMGFHVDPKARGR------------YFLDTNNGPPYAKGENFTSISRQLKGRTFVNDDIIDKLIGT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VEY9-1", "uniprot_id": "Q9VEY9_DROME", "id": "Q9VEY9-1", "name": "", "aln": "------------MGSLTGMHISHWLLWTCLLLLGAAGTDASVD-----------------------------------------------YFAYAPGKCEVSISDVIQGMIT---TEAGVILGRPRPSQTKLLRYDLYTPLNPEERQLLRPG-----------DLTMLRNSHFNPKWPVRVSIHGWAGK--SVTCSNAAIKDAYLS------RGN------YNVIILDWSRQSLDISYPRVSKQLPSIAANVAKMLRFLHDNTGVPYEQIYMIGHSAGSHISGLTGKLLRPHRLGA--IFALDPAGLTQL-SLGPEERLDVNDALYVESIHTDLTLLGNPSTKLSHASFFANWGL-GQPHCP----NATATEFDFVCDHFAAMFYFAESVR--QPKSFAALRCSSAKSVLSATCNCNVGGSEKYAVNTCTGNEFMGGEPAVPKRGIFYLSTRPQSPYGTSDGLVHIKRPRPSTIRETANRRSIG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLU1-1", "uniprot_id": "Q9VLU1_DROME", "id": "Q9VLU1-1", "name": "Lipase domain-containing protein", "aln": "MSSNALACICNVINPCRNEVSTTFVVVQWLITGFAALAQVVRP-------------------VLLLFGIRGEVALN-----------------QEDYNKTWIYMPNGQGKPE--VAYLVEPPPENRINLPQLIKFELYGSDSSSSADFWIDENNFEFPQRHKRDTWQEMAEKFNPELDTKILVHGWKSS--TMSNSIQSIRGAYIE------RGQ------VNVFAINWKDQADNIYYLTPARYTVQVGRAVAKLIDLLVEEKDADPNRIHLIGHSLGAHIMGYAGSYT-KYRVNR--ITGLDPARPAFEDCIGPENHLDDTDANFVDVIHSCAGYLGFRKP-IGMVDFYPNGGGPPQPGCK------ELSQIFTGCSHGRSYEYYAESIN--SPKGFYGVPCSGLDELKGKNCT---GGKILMGDPVPREARG-----------IFFVKTANKPSYALGIDDLWSN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VBQ2-1", "uniprot_id": "Q9VBQ2_DROME", "id": "Q9VBQ2-1", "name": "Lipase domain-containing protein", "aln": "--------MMMRMRNRGGKRLQANYFDTQMPLLSSGLMSPGQLPILDEQHGRQEQLERHYLAHGPSSVEQQLLRLQPDYKLLYSAEHHTYFHLHTLVPQDNANRQTGPLKSEKESPHRRLFQQVVGNTLTAAFGLNVMNKGDQEQNQQFTSEPVN------LYDAASLRRSRFSPFNPTRILIHGWLGN--ENANMYNELLPAYFDLR----NGN------YNIFTVDWGRGAI-ADYITASYRVKPVGQVLAKFVDFLHQEAGMRFEDLQLVGFSMGAHVAGLAGKHLQTGRLRM--IRALDPALPFFR-YAKPKERLTAEDADYVEVLHTSVGSYGFDRP-VGHVDFYANWGS-QQPGCF-----------WHECSHWRAFMLFAESLARDQATGFLSQGCPAAEWQQLTRFHRCPKDTGVMQTMGGDLANVSAEFLAQ-RQGVYYFQTNDQPPYVLAQNASSKRAAHIQENKK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . :**: . : : *:: :: * . . :: : . .:* . *:.: * . . : .**** :: ** :*: ::: * . . :: . * * * * * : : .:: : * :. . .: ", "identical_positions": 22, "similar_positions": 51, "identity": "2.78%" }, { "cls_id": "homologset.agr.RGD:621263", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCG6-1", "uniprot_id": "PBLD1_MOUSE", "id": "Q9DCG6-1", "name": "Phenazine biosynthesis-like domain-containing protein 1", "aln": "--MKLPIFIADAFTATAFRGNPAAVC----LLERTLEEDAHQQIAREMNLSETAFIRKLQPTDSFTQSSRFGLRWFTPVSEVPLCGHATLASAAVLFHKIQNRNSTLTFVTMSGELKARRAEDGIVLDFPVYPTFPQDFHEVEDLIKAAIGDTLVQDIRYSTDTRKLLVRLSDSYDRSFLESLKVNTEPLPAIEKTGKVRGLILTVKGEPGGQTAPYDFYSRYFAPWVGIAEDPVTGSAHTVLSSYWSQQLRKKEMRAFQCS-----RRGGELDISLRPDGR----VDIKGGAVIVLEGTLTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68G31-1", "uniprot_id": "PBLD_RAT", "id": "Q68G31-1", "name": "Phenazine biosynthesis-like domain-containing protein", "aln": "--MKLPIFIADAFTVTAFHGNPAAVC----LLESILQEDAHQQIAREMNLSETAFIRKLQPTDSFSQSSCFGLRWFTPVSEVPLCGHATMASAAVLFHKIKNVNSTLTFVTLSGELKARRAEDGIVLDFPLYPTFPQDFHEVKDLIKAAIGDTTVQDIQYSPDTRKLLVRLSDSYDRSFLESLKVNTEPLPGIEKTGKVKGLILTVKGESGGQTTPYDFYSRYFAPWVGVPEDPVTGSAHTVLSSYWSQQLGKKEMRAFQCS-----CRGGELDISLRPDGR----VDMKGGAAVVLEGMLTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30039-1", "uniprot_id": "PBLD_HUMAN", "id": "P30039-1", "name": "Phenazine biosynthesis-like domain-containing protein", "aln": "--MKLPIFIADAFTARAFRGNPAAVC----LLENELDEDMHQKIAREMNLSETAFIRKLHPTDNFAQSSCFGLRWFTPASEVPLCGHATLASAAVLFHKIKNMNSTLTFVTLSGELRARRAEDGIVLDLPLYPAHPQDFHEVEDLIKTAIGNTLVQDICYSPDTQKLLVRLSDVYNRSFLENLKVNTENLLQVENTGKVKGLILTLKGEPGGQTQAFDFYSRYFAPWVGVAEDPVTGSAHAVLSSYWSQHLGKKEMHAFQCS-----HRGGELGISLRPDGR----VDIRGGAAVVLEGTLTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38765-1", "uniprot_id": "YHI9_YEAST", "id": "P38765-1", "name": "Uncharacterized isomerase YHI9", "aln": "MTLMVPFKQVDVFTEKPFMGNPVAVINFLEIDENEVSQEELQAIANWTNLSETTFL--FKPSD---KKYDYKLRIFTPRSELPFAGHPTIGSCKAFLEFTKNTTATSLVQECKIGAVPITINEGLISFKAPMADYESISSEMIADYEKAIGLKFIKPPALLHTGPEWIVALVEDAETCFNANP--NFAMLAHQTKQNDHVGIILAGPKKEAAIKNSYEMR--AFAPVINVYEDPVCGSGSVALARYLQEVYKFEKTTDITISEGGRLKRNGLMLASIKKEADNSTSYYIAGHATTVIDGKIKV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*: .*.** .* ***.** : * :.:: * **. *****:*: ::*:* :. : ** *** **:*:.**.*:.*. .::. :* .:* . . . ::*:: . . . . *: : *** . :: : :* * : : .* . * * : .. *:**: : .. . .::: *** :.: **** **. ..*: * .: :: : * *.* : *:: :. : * *. *::* :..", "identical_positions": 68, "similar_positions": 95, "identity": "22.44%" }, { "cls_id": "homologset.agr.RGD:621264", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97557-1", "uniprot_id": "KCNV1_RAT", "id": "P97557-1", "name": "Potassium voltage-gated channel subfamily V member 1", "aln": "MDLSPRNRPLLDSSSLDSGSLTSLDSSVFCSEGEGEPLALGDCLTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTDDQESQHESEQDFSQGPCPTVRQKLWDILEKPGSSTAARIFGVISIIFVAVSIVNMALMSAELSWLNL-QLLEILEYVCISWFTGEFILRFLCVKDRCHFLRKVPNIIDLLAILPFYITLLVESLSGSHTTQELENVGRLVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDS-YISVNLRDIYARSIMEMLRLKGRERASTRSSGGDDFWF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZN2-1", "uniprot_id": "KCNV1_MOUSE", "id": "Q8BZN2-1", "name": "Potassium voltage-gated channel subfamily V member 1", "aln": "MDLSPRNRPLLDSSSLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTDDQESQHESEQDFSKGPCPTVRQKLWDILEKPGSSTAARIFGVISIIFVAVSIVNMALMSAELSWLNL-QLLEILEYVCISWFTGEFVLRFLCVKDRCHFLRKVPNIIDLLAILPFYITLLVESLSGSHTTQELENVGRLVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDS-YISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PIU1-1", "uniprot_id": "KCNV1_HUMAN", "id": "Q6PIU1-1", "name": "Potassium voltage-gated channel subfamily V member 1", "aln": "--MPSSGRALLDSP-LDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDL-QLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDS-YISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UV51-1", "uniprot_id": "A0A8N7UV51_DANRE", "id": "A0A8N7UV51-1", "name": "Potassium voltage-gated channel subfamily V member 1", "aln": "---MITDSSSPAEFYEDNASLLSLDSSVFFSEPALPTDDPLEFFIINVGGSRYILSQELLASHPETRLGKL-----------ALSSRDSALDLCDDADFLENEYFFDRNSQTFQYIMNFYKTGHLHVREELCVISFLQEIEYWGIDELRIDSCCRDKYYRRKEMKESLDIRKDADVMD---KEEEDFTGVLCQDLRQRLWDIMENPDSSKAAKTFGTLSMFFVVVSIVNMALISLDFSVIGAPIILDILEYICIIWFTGELVLRFLCVRDKCKFSRSVVNIIDLLAILPFYVTLAVESLHG--ESTELENVGRVVQVLRLMRSLRMLKLGRHSTGLKSLGLTIAQCYEEVGLLMLFLSVGISIFATLEYAIEHDTPETTFTNVPSAWWWATTSMTTVGYGDIRPDTAVGKVMAFICILSGILILALPIAIINDRFSACYFTLKMKEAALRHGEVLKRLTRSSASDMSAIGVNLRDVYARSVLEMLRLQGRERASTRSSAGDLWW-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . *..** ******* ** . : : :******::***: *:..*.****** **:: *.*:*****: ::*******.**:*:*::::*:**:*** *:**.:******:******* *******:*:****:.*:**::**:: : :.*:**: * :**:**:*:*:*.**.**: **.:*::**.***:****:* ::* :. :*:****:** *****::******:*:*:* *.* ************:** **** * : *******:******:*:*************:***:**:*********:**********:*:** *:. *:****.**.*********************:.**::**:*******:********************:****:*: *.**:**:. *:* *.*****:****::*****:**********.** :* ", "identical_positions": 313, "similar_positions": 115, "identity": "61.98%" }, { "cls_id": "homologset.agr.RGD:621266", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0CW02-1", "uniprot_id": "LY6C1_MOUSE", "id": "P0CW02-1", "name": "Lymphocyte antigen 6C1", "aln": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCP-------AGVP---IRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WU67-1", "uniprot_id": "LY6I_MOUSE", "id": "Q9WU67-1", "name": "Lymphocyte antigen 6I", "aln": "MDTSHAIKSCVLILLVTLLCAERAQGLECYQCYGVPFETSCPSFTCPYPDGFCVAQEEEFIANSQRKKVKSRSCHPFCP-------DEIEKKFILDPNTKMNISCCQEDLCNAAVPTGGSSWTTAGVLLFSLGSVLLQTLM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35461-1", "uniprot_id": "LY6G_MOUSE", "id": "P35461-1", "name": "Lymphocyte antigen 6G", "aln": "MDTCHIAKSCVLILLVVLLCAERAQGLECYNCIGVPPETSCNTTTCPFSDGFCVALEIEVIVDSHRSKVKSNLCLPICP-------TTLDNTEITGNAVNVKTYCCKEDLCNAAVPTGGSSWTMAGVLLFSLVSVLLQTFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WQT1-1", "uniprot_id": "A0A087WQT1_MOUSE", "id": "A0A087WQT1-1", "name": "", "aln": "MDSSHATRTCVFILLVALLCAEGAQGLECYCCLGVPLETSCKTMTCPYSDGFCVTQEEEVIVDSHTIKVKSNLCLPICP-------TNPETTEFLGNAVNVKTFCCKEDLCNAAVLTEGSTWTMAGVILFSLGSVHLQTLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35460-1", "uniprot_id": "LY6F_MOUSE", "id": "P35460-1", "name": "Lymphocyte antigen 6F", "aln": "MDSCHTTKSCVLILLVVLLCAERAQGLECYNCLGVSLGIACKSITCPYPDAVCISQQVELIVDSQRRKVKNKLCFPFCP-------ANLENMEILGTTVNVNTSCCKEDLCNAPFSTGGSTWTMTRVLLLNLGSVFLQTLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63318-1", "uniprot_id": "Q63318_RAT", "id": "Q63318-1", "name": "", "aln": "MNRSCAMKSYVLILLLPLLCAERAQGLKCYSCIEVPLNANCSTATCPYSDGVCVSQVLEAVEGSVRRTAKSNLCLPICP-------KFPQRTEILGTVVYTKVSCCNTDLCNAAGPTGGSTWTVAGVLLFSLGSVLLETLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94772-1", "uniprot_id": "LY6H_HUMAN", "id": "O94772-1", "name": "Lymphocyte antigen 6H", "aln": "-MLPAAMKGLGLALLAVLLCSAPAHGLWCQDCTLTTNSSHCTPKQCQPSDTVCASVRITDPSSSRKDHSVNKMCASSCDFVKRHFFSDYLMGFINSGILKVDVDCCEKDLCNGAAGAGHSPWALAGGLLLSLGPALLWAGP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ** ***: *:** * * .. * . * .* .* : .* .. * . * : . **. ****.. : *.*: : :*:.* .. * : ", "identical_positions": 28, "similar_positions": 29, "identity": "19.86%" }, { "cls_id": "homologset.agr.RGD:621267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08700-1", "uniprot_id": "VPS45_RAT", "id": "O08700-1", "name": "Vacuolar protein sorting-associated protein 45", "aln": "MNVVFAVKQYISKMIEDSG----------PGMKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDS-QNREIMKHLKAICFLRPTKENVDSLIQELRRPKYSIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSLNILG---CCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLGECVKQVISK-EYELFEFRR---TEVPPLLLILDRCDDAITPLLNQWTYQAMVHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKRPKEQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNVKRLLQNPKVTEFDAVRLVMLYALHYERHSS-NSLPGLIVDLRSKGVAEKYRKLVSAVVEYGGKRVRGSDLFSPK---DAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKGKLKENLYPYLG--------PSTLRDRPQDIIVFVIGGATYEEALTVYNLNR-TTPGVRIVLGGTTIHNTKSFLEEVLASGLHSRSRESSQATSRSASRR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97390-1", "uniprot_id": "VPS45_MOUSE", "id": "P97390-1", "name": "Vacuolar protein sorting-associated protein 45", "aln": "MNVVFAVKQYISKMIEDSG----------PGMKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDS-QNREIMKHLKAICFLRPTKENVEYLIQELRRPKYSIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSLNILG---CCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLGECVKQVISK-EYELFEFRR---TEVPPLLLILDRCDDAITPLLNQWTYQAMVHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKRPKEQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNVKRLLQNPKVTEFDAVRLVMLYALHYERHSS-NSLPGLIVDLRSKGVAEKYRKLVSAVVEYGGKRVRGSDLFSPK---DAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKGRLKENLYPYLG--------PSTLRDRPQDIIVFIIGGATYEEALTVYNLNR-TTPGVRIVLGGTTIHNTKSFLEEVLASGLHSRSRESSQATSRSANRR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRW7-1", "uniprot_id": "VPS45_HUMAN", "id": "Q9NRW7-1", "name": "Vacuolar protein sorting-associated protein 45", "aln": "MNVVFAVKQYISKMIEDSG----------PGMKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDS-QNREIMKHLKAICFLRPTKENVDYIIQELRRPKYTIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSLNILG---CCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLAECVKQVITK-EYELFEFRR---TEVPPLLLILDRCDDAITPLLNQWTYQAMVHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSS-NSLPGLMMDLRNKGVSEKYRKLVSAVVEYGGKRVRGSDLFSPK---DAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKGRLKENLYPYLG--------PSTLRDRPQDIIVFVIGGATYEEALTVYNLNR-TTPGVRIVLGGTTVHNTKSFLEEVLASGLHSRSKESSQVTSRSASRR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VHB5-1", "uniprot_id": "Q9VHB5_DROME", "id": "Q9VHB5-1", "name": "Vacuolar protein sorting-associated protein 45", "aln": "MNLISGIKLYIEKMCSESG----------PGMKIILLDKETTSIISMAFSQSDMLQREVYLFERLDSGRSNERLKYLKCIVFIRPTKQNIQLLANELRNPKYSAYYIYFSNIIPRTDIKYLAECDESESVREVKELYADYLCVNPNLFSLGIPN---CMANLNWLPDALNRSMQGITAVLLSLKLNPVIRYRAGSQAAQLLAKLIYEQITK-ESSLFDFRSNMDGAAPPLLLVLDRRDDPVTPLLHQWTYQAMVHELLHIKNNRLDLSNCPNVPKDFKELVLSGDQDDFYGNNMYANYGEIGSTIKQLMEEFQR-KANDHKKVESIADMKNFIESYPQFKKMSGTVQKHLCVIGELSALSNKRNLFEVSELEQEIACKAEHSAQLQRIKKLIADERVSIDDALKLVALYALRYERHAN-CDTSGLLQIIKTRGG---RAAIVPSLIEYAGTHVRQGDLFNMVRITDAVKLTRNLIKGLKGVENVFTQHTPLLKETLEDVFKGRELDPLFPAINSE------LVPFRRPPQEVVVFIIGGATYEEALAVHQLN---NAGYKVILGGTTIHNSQSFIQEVVAATSGIQFKHTKSMIKYCSTDNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38932-1", "uniprot_id": "VPS45_YEAST", "id": "P38932-1", "name": "Vacuolar protein sorting-associated protein 45", "aln": "MNLFDVADFYINKIVTSQSKLSVANVNEHQRIKVLLLDKNTTPTISLCATQSELLKHEIYLVERIEN-EQREVSRHLRCLVYVKPTEETLQHLLRELRNPRYGEYQIFFSNIVSKSQLERLAESDDLEAVTKVEEIFQDFFILNQDLFSFDLQPREFLSNKLVWSEGGLTKCTNSLVSVLLSLKIKPDIRYEGASKICERLAKEVSYEIGKNERTFFDFPV---MDSTPVLLILDRNTDPITPLLQPWTYQSMINEYIGIKRNIVDLSKVPRIDKDLEKVTLSSKQDAFFRDTMYLNFGELGDKVKQYVTTYKDKTQTN-SQINSIEDIKNFIEKYPEFRKLSGNVAKHMAIVGELDRQLKIKNIWEISEIEQNLSAHDANEEDFSDLIKLLQNEAVDKYYKLKLACIYSLNNQTSSDKIRQLVEILSQQLPPEDVNFFHKFKSLFSRQDKMTQSNHDKDDILTELARRFNSRMNSKSNTAENVYMQHIPEISSLLTDLSKNALFRDRFKEIDTQGHRVIGNQQSKDIPQDVILFVIGGVTYEEARLVHDFNGTMNNRMRVVLGGTSILSTKEYMDSIRSAK--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:. . **.*: ... :*::*:**:** :*: :**::*::*:**.**::. ...* ::*:.: :::**::.:: : .***.*:* * *:***::.::::: ***.*: * * :*:*:: *:: :* .***:.: * *.: :.:.::***** * ***. .*: .: *.: : * * * :*:* .*:**:*** *.:****: ****:*::* : *:.* :***. * : **:.::.**..:* *: :.** *:.*:*..:*: : :: .: .:::** *:* *:*.**:*:*:**.* **: ::***. . :*: *:**:**:::.: :. :. : :*: : * :*. :*:*. : :. : : . ::.. .. .: .. . * :. .: . : .***: ** * : . * .: *. : :. : **::::*:***.***** *:::* . :::****:: .::.:::.: :: ", "identical_positions": 155, "similar_positions": 221, "identity": "25.75%" }, { "cls_id": "homologset.agr.RGD:621269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z144-1", "uniprot_id": "LEG2_RAT", "id": "Q9Z144-1", "name": "Galectin-2", "aln": "MSEKFEVTNLNMKSGMSLKIKGKIHNDVNSFTINLGQ------GKETLNLHFNPRFNESTIVCNTLD-GSSWGQEQR-ENHSC------FSPGSEVKLTLTFQDKDFKVTLPDG----------------------------------HSLTFP---------------------------------------------NRLGHNHLRYLS-------------------------------MDG-LQISSFKLE-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQW5-1", "uniprot_id": "LEG2_MOUSE", "id": "Q9CQW5-1", "name": "Galectin-2", "aln": "MSEKFEVKDLNMKPGMSLKIKGKIHNDVDRFLINLGQ------GKETLNLHFNPRFDESTIVCNTSE-GGRWGQEQR-ENHMC------FSPGSEVKITITFQDKDFKVTLPDG----------------------------------HQLTFP---------------------------------------------NRLGHNQLHYLS-------------------------------MGG-LQISSFKLE-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05162-1", "uniprot_id": "LEG2_HUMAN", "id": "P05162-1", "name": "Galectin-2", "aln": "MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQ------GTDKLNLHFNPRFSESTIVCNSLD-GSNWGQEQR-EDHLC------FSPGSEVKFTVTFESDKFKVKLPDG----------------------------------HELTFP---------------------------------------------NRLGHSHLSYLS-------------------------------VRGGFNMSSFKLKE------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPU6-1", "uniprot_id": "Q9VPU6_DROME", "id": "Q9VPU6-1", "name": "Galectin", "aln": "MNVWKAKVLTEVPFGHVLIVSGRVKPHPNKISLDLTDNVNAQNESETVFLKIEANFREGQIIRSMFQPGGGWQQEEISKNWKCDGPKNPLQPGQSFTFRVAVLQRCFEIYVNDQLYGSFEFVKFPKQINYVRTYGDFEKITQFHHRMLFPLVFPRTLMCPDKVAFQSDVPRRYETGTVVAMECIAKGPPTTEFSICFQCNDTGRTVLRFHVNFDRTTVSRSYQREDNSFALSDEETEGEFPFVRGKLFKIAFGLGDRAFLIAVNGQYFTYYNFPGRPFSISTLKCFTNEVGDFAVRSLEYHSDSPLLARVEKLSII", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :: * * :.* : : : ::* : .:.: *:::..* *. *: . : *. * **: :: * :.**....: ::. . *:: : * . *.** * *:. * : : * : :* * ", "identical_positions": 27, "similar_positions": 50, "identity": "8.54%" }, { "cls_id": "homologset.agr.RGD:621270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84077-1", "uniprot_id": "ARF1_HUMAN", "id": "P84077-1", "name": "ADP-ribosylation factor 1", "aln": "MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84079-1", "uniprot_id": "ARF1_RAT", "id": "P84079-1", "name": "ADP-ribosylation factor 1", "aln": "MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84078-1", "uniprot_id": "ARF1_MOUSE", "id": "P84078-1", "name": "ADP-ribosylation factor 1", "aln": "MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61209-1", "uniprot_id": "ARF1_DROME", "id": "P61209-1", "name": "ADP-ribosylation factor 1", "aln": "MGNVFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRDAVLLIFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLKNANR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11076-1", "uniprot_id": "ARF1_YEAST", "id": "P11076-1", "name": "ADP-ribosylation factor 1", "aln": "MGLFASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVVDSNDRSRIGEAREVMQRMLNEDELRNAAWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQATCATSGEGLYEGLEWLSNSLKNST-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P19146-1", "uniprot_id": "ARF2_YEAST", "id": "P19146-1", "name": "ADP-ribosylation factor 2", "aln": "MGLYASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVIDSNDRSRIGEAREVMQRMLNEDELRNAVWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQSTCATSGEGLYEGLEWLSNNLKNQS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ::**..***:***********.*****:********::*************:***************:**.*****::**:*:***:*****.*:.**** : *** *****:*. *:********:**.*****:******:*:* *:**:******:******:****.*:* . ", "identical_positions": 136, "similar_positions": 36, "identity": "74.73%" }, { "cls_id": "homologset.agr.RGD:621271", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P11076-1", "uniprot_id": "ARF1_YEAST", "id": "P11076-1", "name": "ADP-ribosylation factor 1", "aln": "MGLFASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVVDSNDRSRIGEAREVMQRMLNEDELRNAAWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQATCATSGEGLYEGLEWLSNSLKNST-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P19146-1", "uniprot_id": "ARF2_YEAST", "id": "P19146-1", "name": "ADP-ribosylation factor 2", "aln": "MGLYASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVIDSNDRSRIGEAREVMQRMLNEDELRNAVWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQSTCATSGEGLYEGLEWLSNNLKNQS-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q8BSL7-1", "uniprot_id": "ARF2_MOUSE", "id": "Q8BSL7-1", "name": "ADP-ribosylation factor 2", "aln": "MGNVFEKLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLKNQK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84082-1", "uniprot_id": "ARF2_RAT", "id": "P84082-1", "name": "ADP-ribosylation factor 2", "aln": "MGNVFEKLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQDLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLKNQK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61209-1", "uniprot_id": "ARF1_DROME", "id": "P61209-1", "name": "ADP-ribosylation factor 1", "aln": "MGNVFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRDAVLLIFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLKNANR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "I3L3L1-1", "uniprot_id": "AL17B_HUMAN", "id": "I3L3L1-1", "name": "Putative ADP-ribosylation factor-like protein 17B", "aln": "MGNIFEKLFKSLLGKKKMRILILSLDTAGKTTILYKLKLGETVPAVPTVGFCVETVEYKNNTFAVWDVGSHFKIRPLWQHFFQNTKGARSPGSTHQGSLASGVLPIKCSHVEFGMWKGGRSHPFLPHSSR-CAGSGGQLDSILPHQSPAWGPWGCKDLSSGFPSFLTSSILWKSAVLLTPKA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :**..*:*:*:****::.** *****:******** :.::**:** ****:*** :*:*****.: :**.**:*:::**:* .::: . . . : . :.. * :.. * ...:: . * :* * : .: . * ..: * * * . . ", "identical_positions": 60, "similar_positions": 58, "identity": "32.97%" }, { "cls_id": "homologset.agr.RGD:621272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62665-1", "uniprot_id": "LEG8_RAT", "id": "Q62665-1", "name": "Galectin-8", "aln": "------------------------------------------------------------------------------------MLSLSNLQNIIYNPTIPYVS------------------------------------TITEQLKPGSLIVIRGHVPKDSERFQVDFQH--GNSLKPRADVAFHFNPRFKRSNCIVCNTLTNEKWGWEEITHDMPFRKEK--SFEIVIMVLKNKFHVAVNGKHILLYAHRINPEKIDTLGIFGKVNIHSIGFRFSSDLQSMETST---------------------------LGLTQISKENIQKSGKLH---------LSLPFEARLNAS--MGPGRTVVVKGEVNTNATSFNVDLVAGR----SRDIALHLNP--------RLNVKAFVRNSFLQDAWGEEERNITCFPFSSGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKDLSSIDTLAVDGDIRLLDVRSW-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL15-1", "uniprot_id": "LEG8_MOUSE", "id": "Q9JL15-1", "name": "Galectin-8", "aln": "------------------------------------------------------------------------------------MLSLNNLQNIIYNPIIPYVG------------------------------------TITEQLKPGSLIVIRGHVPKDSERFQVDFQL--GNSLKPRADVAFHFNPRFKRSSCIVCNTLTQEKWGWEEITYDMPFRKEK--SFEIVFMVLKNKFQVAVNGRHVLLYAHRISPEQIDTVGIYGKVNIHSIGFRFSSDLQSMETSA---------------------------LGLTQINRENIQKPGKLQ---------LSLPFEARLNAS--MGPGRTVVIKGEVNTNARSFNVDLVAGK----TRDIALHLNP--------RLNVKAFVRNSFLQDAWGEEERNITCFPFSSGMYFEMIIYCDVREFKVAINGVHSLEYKHRFKDLSSIDTLSVDGDIRLLDVRSW-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00214-1", "uniprot_id": "LEG8_HUMAN", "id": "O00214-1", "name": "Galectin-8", "aln": "-----------------------------------------------------------------------------------MMLSLNNLQNIIYNPVIPFVG------------------------------------TIPDQLDPGTLIVIRGHVPSDADRFQVDLQN--GSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREK--SFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASS---------------------------LELTEISRENVPKSGTPQ---------LRLPFAARLNTP--MGPGRTVVVKGEVNANAKSFNVDLLAGK----SKDIALHLNP--------RLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VPI6-1", "uniprot_id": "Q9VPI6_DROME", "id": "Q9VPI6-1", "name": "Galectin", "aln": "MTAIILLACHSVRELVDLSDALWQNTFNIERSLNYYRIKRRLELFRFHCRELWLRQVSKTSDPMHRKAGIDFAAIEAGADCVLNMDAFDDTTTELHKRFLQAEGTRPFPSDCISGIEVVDGNEFKASFYEYADAVPKYFNDQIGKLSEGISFTVTGNLSVNCERFSINLVYNNDS-----RDVALHINPRLPQN-YIVRNTKVQDIWGNEEVSSALPFLLSRGEEFSIQVLVTEACYMISVNGQHFAAYTHRIPYRDVRILEVKGDVSNVEMKRTLVLKYPERLPQSEANNIELHIDDGINEIDASVEETVKIPHEWCIISAPNTQSDSSPKRNNSSNDLGLTLPYYG-ALPPNSLVDGRCLKIEGRVRLLPHSFYINLQQGQDIWPHPVIAFHLNPRFSKASSGAIGKAVVCRNAWLNGAWAQEERSEFDTNFRPGRSFCLAIVCTKTSFEVYVNRQFMTDFKYKVS-PEVVDTVYIQGDVKLWNVTLEKNQMIKGKNMRVYQN----PWFFSE------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPI7-1", "uniprot_id": "Q9VPI7_DROME", "id": "Q9VPI7-1", "name": "Galectin", "aln": "------------------------------------------------------------------------------------MSVYPGACTVALRRVMDAMS---------------------LFYEKRSEAHRRKHFKVIQCPRPGLCFVFHGMILMACEHFVIDFLTKQGSEICEECDVLLQIGSRLPQN-YITRNSRLKGKWGPEENSSYLTFQLNRGKSFWMQILLTEECFFISVNGYHFAKYFHRMPYRWLEAVDVLGDVSDIVIDTYYVSEYPIRLTHS--------LPRPIPHSNKLPRDGENVETEWMVLSSLAKMSSKKFLYQPS-----LPLPFYGKLLKENFLIEGSSLRIEGRVRLMPQRFSIAFQKGQEIWPQPTVSFYFSPCFLRSRHDKIGTAIITRRAYLNGDWVNCTVSRLNTSLRPGGAFVIVIACRDSYYELFVNNRSLFHFKYQMR-PECVDIVNIRGDIKLWEVAIQGNTTYKKPKVRSAMERAISAWKRAEIPQLQI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . : . * :.. * : .::* ::: .. ** :::..*: : *. *: : ** ** : .* .: .* : .:: : : ::*** * * **: . : : : *.*. : . . : :. . . * **: . : * : ::*.*. . * : : *: :::::.* :. . *.::*: * : . : .* * : * * ::: :* .:*::. . :* : : **::* :* ", "identical_positions": 47, "similar_positions": 101, "identity": "9.02%" }, { "cls_id": "homologset.agr.RGD:621273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61204-1", "uniprot_id": "ARF3_HUMAN", "id": "P61204-1", "name": "ADP-ribosylation factor 3", "aln": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61206-1", "uniprot_id": "ARF3_RAT", "id": "P61206-1", "name": "ADP-ribosylation factor 3", "aln": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61205-1", "uniprot_id": "ARF3_MOUSE", "id": "P61205-1", "name": "ADP-ribosylation factor 3", "aln": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61209-1", "uniprot_id": "ARF1_DROME", "id": "P61209-1", "name": "ADP-ribosylation factor 1", "aln": "MGNVFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRDAVLLIFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLKNANR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11076-1", "uniprot_id": "ARF1_YEAST", "id": "P11076-1", "name": "ADP-ribosylation factor 1", "aln": "MGLFASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVVDSNDRSRIGEAREVMQRMLNEDELRNAAWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQATCATSGEGLYEGLEWLSNSLKNST-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P19146-1", "uniprot_id": "ARF2_YEAST", "id": "P19146-1", "name": "ADP-ribosylation factor 2", "aln": "MGLYASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVIDSNDRSRIGEAREVMQRMLNEDELRNAVWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQSTCATSGEGLYEGLEWLSNNLKNQS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .:*:..*:*:***********.*****:********::*************:***************:**.*****::**:*:***:*****.*:.**** : *** *****:*. *:********:**.*****:******:*:* *:**:******:******:**:*.*** . ", "identical_positions": 134, "similar_positions": 38, "identity": "73.63%" }, { "cls_id": "homologset.agr.RGD:621274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P1B1-1", "uniprot_id": "XPP1_MOUSE", "id": "Q6P1B1-1", "name": "Xaa-Pro aminopeptidase 1", "aln": "---------------------------------------------------------------MAPKVTSELLRQLR------------------------------QAMRNSEYVAEP-IQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIIT-----------EEHAAMWTDGRYFLQAAKQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSR-----------VGVDPLIIPTDYWKKMAKVLRS-----AGHHLVPVKENLVDKIWT---DRPERPCKPLLTLGLDYTGISWKEKVADLRLKMAERS------IAWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIVGLETIMLFID---GDRVDAPGVKQHLLLDLGLEAEYRIQVLPYKSILSELKALCADLSPREKVWVSDKASYAVSEAIPK--DHRCCMPYTPICIAKAVKNSAESDGMRRAHIKDAVALCELFNWLEQEVP-KGG-VTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEP-LEAGMIVTDEPGYYEDGAFGIRIENVVLVVPAKTKYNFNNRGSLTFEPLTLVPIQTKMIDVNALTDKECDWLNSYHQTCRDVVGKELQSQGRQEALEWLIRETEPVSRQH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54975-1", "uniprot_id": "XPP1_RAT", "id": "O54975-1", "name": "Xaa-Pro aminopeptidase 1", "aln": "---------------------------------------------------------------MAPKVTSELLRQLR------------------------------QAMRNSECVAEP-IQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIIT-----------EEHAAMWTDGRYFLQAAKQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSR-----------VGVDPLIIPTDYWKKMAKVLRS-----AGHHLVPVKENLVDKIWT---DRPERPCKPLLTLGLDYTGISWKEKVADLRLKMAERS------IVWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLERIMLFID---GDRIDAPGVKQHLLLDLGLEAEYKIQVLPYKSILSELKTLCADLSPREKVWVSDKASYAVSEAIPK--DHRCCMPYTPICIAKAVKNSAESAGMRRAHIKDAVALCELFNWLEQEVP-KGG-VTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPIPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEP-LEAGMIVTDEPGYYEDGAFGIRIENVVLVVPAKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDALTDKECDWLNSYHQTCRDVIGKELQTQGRQEALEWLLRETEPISRQH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQW7-1", "uniprot_id": "XPP1_HUMAN", "id": "Q9NQW7-1", "name": "Xaa-Pro aminopeptidase 1", "aln": "---------------------------------------------------------------MPPKVTSELLRQLR------------------------------QAMRNSEYVTEP-IQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIIT-----------EEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSR-----------VGVDPLIIPTDYWKKMAKVLRS-----AGHHLIPVKENLVDKIWT---DRPERPCKPLLTLGLDYTGISWKDKVADLRLKMAERN------VMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFID---GDRIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVSETIPK--DHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVP-KGG-VTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEP-LEAGMIVTDEPGYYEDGAFGIRIENVVLVVPVKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKELQKQGRQEALEWLIRETQPISKQH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJG0-1", "uniprot_id": "XPP_DROME", "id": "Q9VJG0-1", "name": "Xaa-Pro aminopeptidase ApepP", "aln": "----------------------------------------------------------------MKRSTTQILTRLR------------------------------ELMLRAQVGDSCGISAYIVPSDDAHQSEYQCQHDERRSFVSGFDGSAGTAVIT-----------TETALLWTDGRYYQQAEKQLDSNWVLMRDGLSATPSIGAWLAKNLPKGSF-----------VGVDPRLLSFRVWKPIETELSS-----AECQLVPIEGNLIDEVWGE--DQPPQTSNKIITLKLEHSGVTIAKKWDVVRQQLKEKN------ADALVVSALDEIAWFLNLRGSDIDFNPVFFSYLIVTNDELLLFVD---SGKLPTDFVQHQK------ENNVQISVLPYASIGIEISKIVSTRES--KIWIAPTSSYYLTALIPK--SRR-IQEVTPICVLKAIKNDVEIAGFINSHIRDGVALCQYFAWLEDQVN-KGAEVDEMSGADKLESFRSTKDKYMGLSFTTISASGPNGSVIHYHPKKETNRKINDKEIYLCDSGAQYLDGTTDVTRTLHFGEPTEFQKEAYTRVLKGQLSFGSTVFPAKVKGQVLDTLARKALWDVGLDYGHGTGHGVGHFLNVHEGPMGVGIRLMPDDPGLQANMFISNEPGFYQDGEFGIRVEDIVQIVPGQVAHNFSNRGALTFKTITMCPKQTKMIKKELLSDAEVKLLNSYHQQVWDTLSPILSREGDEFTLSWLKKEVQPI----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07825-1", "uniprot_id": "FRA1_YEAST", "id": "Q07825-1", "name": "Putative Xaa-Pro aminopeptidase FRA1", "aln": "MTSKPSTSDGRAHSISHVPGTHMRGTSASHSPRPFRPCADCTCSPGLLSRQGRRASLFLRQLENSRRSSSMLLNELKGAGGGSSAGNGSVYSCDSLCAVNREVNTTDRLLKLRQEMKKHDLCCYIVPSCDEHQSEYVSLRDQRRAFISGFSGSAGVACITRDLLNFNDDHPDGKSILSTDGRYFNQARQELDYNWTLLRQ-NEDPITWQEWCVREALEMAKGLGNKEGMVLKIGIDPKLITFNDYVSFRKMIDTKYDAKGKVELVPVEENLVDSIWPDFETLPERPCNDLLLLKYEFHGEEFKDKKEKLLKKLNDKASSATTGRNTFIVVALDEICWLLNLRGSDIDYNPVFFSYVAINEDETILFTNNPFNDDISEYFKINGIEVRPYEQIWEHLTKITSQASSAEHEFLIPDSASWQMVRCLNTSTNANGAIAKKMTAQNFAIIHSPIDVLKSIKNDIEIKNAHKAQVKDAVCLVQYFAWLEQQLVGREALIDEYRAAEKLTEIRKTQRNFMGNSFETISSTGSNAAIIHYSPPVENSSMIDPTKIYLCDSGSQFLEGTTDITRTIHLTKPTKEEMDNYTLVLKGGLALERLIFPENTPGFNIDAIARQFLWSRGLDYKHGTGHGIGSFLNVHEGPMGVGFRPHLMNFPLRAGNIISNEPGYYKDGEYGIRIESDMLIKKATEKGNF-----LKFENMTVVPYCRKLINTKLLNEEEKTQINEYHARVWRTIVHFLQPQS--ISYKWLKRETSPL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :* .*: . : : . : .**:** * ***** . * **:*:***.****.* ** : : *****: ** :::* **.*:: . . : * . : : :*:** ::. : : . : : . .*:*:: **:*.:* * :..: :: * :. * .* : :: :: ::* *****.*::******::.******* : : :** : .. : . : :: . : * . : . . : .:: * :. :** : *::**. * . .::::*.*.* : * ***.:: : . : * .*:* .:* : .::. ** ***::*.*.::*** * *.. :. ::** ***:*: :****:***:*: ** : : :* **** ::. :** . * :*::**. **. **** ******:* ******** *:. : : *.*. ::::***:*:** :***:*. : : ** *.*: :*: * *:*. . *.: * :*.** .: *. :. : .** :*..*: ", "identical_positions": 183, "similar_positions": 196, "identity": "24.05%" }, { "cls_id": "homologset.agr.RGD:621275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61750-1", "uniprot_id": "ARF4_MOUSE", "id": "P61750-1", "name": "ADP-ribosylation factor 4", "aln": "MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61751-1", "uniprot_id": "ARF4_RAT", "id": "P61751-1", "name": "ADP-ribosylation factor 4", "aln": "MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAAVLQKMLLEDELQDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18085-1", "uniprot_id": "ARF4_HUMAN", "id": "P18085-1", "name": "ADP-ribosylation factor 4", "aln": "MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40945-1", "uniprot_id": "ARF4_DROME", "id": "P40945-1", "name": "ADP ribosylation factor 4", "aln": "MGLTISSLLTRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRITEAERELQNMLQEDELRDAVLLVFANKQDLPNAMTAAELTDKLRLNQLRNRHWFIQSTCATQGHGLYEGLDWLSAELAKK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11076-1", "uniprot_id": "ARF1_YEAST", "id": "P11076-1", "name": "ADP-ribosylation factor 1", "aln": "MGLFASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVVDSNDRSRIGEAREVMQRMLNEDELRNAAWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQATCATSGEGLYEGLEWLSNSLKNST", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P19146-1", "uniprot_id": "ARF2_YEAST", "id": "P19146-1", "name": "ADP-ribosylation factor 2", "aln": "MGLYASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVIDSNDRSRIGEAREVMQRMLNEDELRNAVWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQSTCATSGEGLYEGLEWLSNNLKNQS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *.*::.***:*:*********.*****:********::*************:****.**********:**.**:**::**:*:***:*****.** * :*.** ***::*. *:********:**: :*:*:** *:.:*** *::*:****.* ******:*** .* : ", "identical_positions": 121, "similar_positions": 42, "identity": "66.85%" }, { "cls_id": "homologset.agr.RGD:621276", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AC58GIR7-1", "uniprot_id": "A0AC58GIR7_DANRE", "id": "A0AC58GIR7-1", "name": "", "aln": "---------MSQQYFRRTENFLYRDRIPLRIVRSESELSPLEKAYLWAVEKGDYGSVKQALIEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK--KPSGGMQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSMPQPHQVRCNCMECVSSSDVDSLRHSRSRLNIYRALASPSLVALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSQQCKQFAKDLLDQTRSSRELELILNYK--DDINLLEDEGINDLARLKLAIKYHQKEFVAQPNCQQLLASRWYDEFPGWRRRHWASKFMTCIFIGLLFPFFSLFYLIAPKSHYGLFIRKPFIKFICHTASYLTFLFLLLLASQHVN-----------RNLLDQDENSDCKNENLRQNLAPTTVEWMILPWVLGFVWAEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVALS---------KYN-NQCRDEWDMWHPALVGEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYESDGKT---SNNVTCKGIRCSEQNN--------AFTTMFETLQSLFWSIFGLVALHVTNVDAKHDFTEFVGATMFGTYSIISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNVVPSPKSAWYLIRWIKTHCFKIKQRKRTETLGSLGVRGHFLLMLYSFIFHYMLTNFLFTEYYIYINNAFGFHYHIIKQSVLKKAIQLFSFVQIRAAENVRTNRQYQEVLRNLVKRYVAARIRDAKKEEGLTEDNFKELKQDISSFRYEVMGMMKGTKTGMSTSK-----------------------------------------------------------GNTAESSLVYPENALKCNSTSTGSTLKGKMRLQSITNTMIQEGGPKAWKPTG----CSNLADSSVPNK-------NISHQLN-------------CKGPN-------NPGE-----------------------MYSVSEEAGESESE--------------------------------------------------EQGDGKQAENLDCK---------------KKKNQNKET------------------EKDGV----------NNDVEEDEELTYMRYMCEEE---------------------------------MNEGNEGETSRL---------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IM91-1", "uniprot_id": "A0A0R4IM91_DANRE", "id": "A0A0R4IM91-1", "name": "", "aln": "---------MSQLYFRRTDNSSYRDRIPLRIVRAESELSTQEKSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK--KPSGEKQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKAEYEELSHQCKHFAKDLLDQTRSSRELELILNFR--DDMNLLQDEANNELARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQHIV-----------SNNPD------------RQGPKPTTVEWMILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYV---------KYSGCKPRDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEN-------SEGMTCKGIRCERQNN--------AFSTLFETLQSLFWSIFGLISLYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSICYLITWIKVHVFKRRS-KRKETFGTLGRR---------------------------------------------------------AAENVRLNHQYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVIGMMKGNRKSTRANK-----------------------------------------------------------SDTSASDVSHPEGSLQYSSALK---QNSKLHLYDVTTALQQQNSEEAKASLG----CLANGSAVVLTE-------PILKDKARSDFPKDFTDFGLFPKKQ-------NPNK-----------------------IYSLAEEATESDPD--------------------------------------------------ILDWGKEDKPLAGK---------------VEQDVNESK------------------CLMEE----------DERVLEEQEMEHIASSHEH-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O35119-1", "uniprot_id": "TRPC4_RAT", "id": "O35119-1", "name": "Short transient receptor potential channel 4", "aln": "---------MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK--KPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYR--DDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-----------RSDLN------------RQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---------KYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEE-------TKGLSCKGIRCEKQNN--------AFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTDFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTHLCKKKMRRKPESFGTIGRR---------------------------------------------------------AADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLSTIQS------------------------------------------------------------ANAASSAS-SADSDEKSHSEGNGKDKRKNLSLFDLTTLIHPRSAVIASERHN----LSN-GSALVVQE-------PPREKQRKVNFVADIKNFGLFHRRSKQNAAEQNANQ-----------------------IFSVSEEITRQQAAG-----------------------------------------------ALERNIQLESKGLASRGDRSIPGLNEQCVLVDHRERNTDT------------------LGLQVGKRVCSSFKSEKVVVEDTVPIIPKEKHAQE---------------------------------EDSSIDYDLSPTDTVAHEDYVTTRL--------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUQ5-1", "uniprot_id": "TRPC4_MOUSE", "id": "Q9QUQ5-1", "name": "Short transient receptor potential channel 4", "aln": "---------MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK--KPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYR--DDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-----------RSDLN------------RQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---------KYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEE-------TKGLSCKGIRCEKQNN--------AFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTHLCKKKMRRKPESFGTIGRR---------------------------------------------------------AADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLSTIQS------------------------------------------------------------ANAAS----SADSDEKSQSEGNGKDKRKNLSLFDLTTLIHPRSAAIASERHN----LSN-GSALVVQE-------PPREKQRKVNFVADIKNFGLFHRRSKQNAAEQNANQ-----------------------IFSVSEEITRQQAAG-----------------------------------------------ALERNIELESKGLASRGDRSIPGLNEQCVLVDHRERNTDT------------------LGLQVGKRVCSTFKSEKVVVEDTVPIIPKEKHAHE---------------------------------EDSSIDYDLSPTDTAAHEDYVTTRL--------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBN4-1", "uniprot_id": "TRPC4_HUMAN", "id": "Q9UBN4-1", "name": "Short transient receptor potential channel 4", "aln": "---------MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK--KPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYR--DDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-----------RSDLN------------RQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---------KYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEE-------TKGLTCKGIRCEKQNN--------AFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRR---------------------------------------------------------AADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQS------------------------------------------------------------ANASKESSNSADSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHN----ISN-GSALVVQE-------PPREKQRKVNFVTDIKNFGLFHRRSKQNAAEQNANQ-----------------------IFSVSEEVARQQAAG-----------------------------------------------PLERNIQLESRGLASRGDLSIPGLSEQCVLVDHRERNTDT------------------LGLQVGKRVCP-FKSEKVVVEDTVPIIPKEKHAKE---------------------------------EDSSIDYDLNLPDTVTHEDYVTTRL--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJJ7-1", "uniprot_id": "TRPG_DROME", "id": "Q9VJJ7-1", "name": "Transient receptor potential-gamma protein", "aln": "---------------------MMEEENTIRPHQEIRQLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNHD--PTGPVYEHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLN-----TMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMIYNSHATDLPRERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDPNACIVWRRFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLKTIRRK---------------------------------------------------------AQQASDRDFKYQQIMRNLVRRYVTVEQRKAESQ-GVTEDDVNEIKQDISAFRCELVEILKNSGMDTNVTAGQGGGGGGKKNRQKERR--------------------------------LMKGFNIAPPGSTGSLAPVAEFSTSLDNYDNQHEILSSTLSTLFTPNFMHKRQQSQAGSGGG----GSESPTTPTAPQGTQGAAMTASSQVTKYNKSALKPYNKRIAGHKKRWGTLIEAAK-----------------------VGNVSKMLGRSKSEDSVCNSSHTSTPVHGQMRVTYAQNSPQQEYGYHGETSSTTISTPTPTISVVSNSPAAHAGVGSHFFHTTSGLTAIAALKRKRKKFSSSKNICPVTESVAAANAAEILNDKTLKRVSSYPAAEAGVQHNPAQLVKPRRHEQT---------------------------------QSQHDSVETNSTFTLSIDPSNTSVNSREPLISTSCVSTTGAIG--------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19334-1", "uniprot_id": "TRP_DROME", "id": "P19334-1", "name": "Transient receptor potential protein", "aln": "MG---------SNTESDAEKALGSRLDYDLMMAEEYILSDVEKNFILSCERGDLPGVKKILEEYQGTDKFNINCTDPMNRSALISAIENENFDLMVILLEHNIEVGDALLHAISEEYVEAVEELLQWEETNHKEGQPYSWEAVDRSKSTFTVDITPLILAAHRNNYEILKILLDRGATLPMPHDVKCGCDECVTSQMTDSLRHSQSRINAYRALSASSLIALSSRDPVLTAFQLSWELKRLQAMESEFRAEYTEMRQMVQDFGTSLLDHARTSMELEVMLNFNHEPSHDIWCLGQRQTLERLKLAIRYKQKTFVAHPNVQQLLAAIWYDGLPGFRRKQASQQLMDVVKLGCSFPIYSLKYILAPDSEGAKFMRKPFVKFITHSCSYMFFLMLLGAASLRVVQITFELLA--FPWMLT----MLEDWRKHERGSLPGPIELAIITYIMALIFEELKSLYSDGLFEYIMDLWNIVDYISNMFYVTWILCRATAWVIVHRDLWFRGIDPYFPREHWHPFDPMLLSEGAFAAGMVFSYLKLVHIFSINPHLGPLQVSLGRMIIDIIKFFFIYTLVLFAFGCGLNQLLWYYAELEK----NKCYHLHPDVADFDDQEKACTIWRRFSNLFETSQSLFWASFGLVDLVSFDLAGIKSFTRFWALLMFGSYSVINIIVLLNMLIAMMSNSYQIISERADTEWKFARSQLWMSYFEDGGTIPPPFNLCPNMKMLRKTLGR--KRPSRTKSFMRK--------------------------------------------------------------------SMERAQTLHDKVMKLLVRRYITAEQR-RRDDYGITEDDIIEVRQDISSLRFELLEIFTNNNWDVPDIEKKSQGVARTTKGKVMERRILKDFQIGFVENLKQEMSESESGRDIFSSLAKVIGRKKTQKGDKDWNAIARKNTFASDPIGSKRSSMQRHSQRSLRRKIIEQANEGLQMNQTQLIEFNPNLGDVTRATRV---AYVKFMRKKMAADEVSLADDEGAPNGEGEKKPLDASGSKKSITSGGTGGGASMLAAAALRASVKNVDEKSGADGKPG------------------TMGKPTDDKKAGDDKDKQQPPKDSKPSAGGPKPGDQKPTPGAGAPKPQAAGTISKPGESQKKDAPAPPTKPGDTKPAAPKPGESAKPEAAAKKEESSKTEASKPAATNGAAKSAAPSAPSDAKPDSKLKPGAAGAPEATKATNGASKPDEKKSGPEEPKKAAGDSKPGDDAKDKDKKPGDDKDKKPGDDKDKKPADNNDKKPADDKDKKPGDDKDKKPGDDKDKKPSDDKDKKPADDKDKKPAAAPLKPAIKVGQSSAAAGGERGKSTVTGRMISGWL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48994-1", "uniprot_id": "TRPL_DROME", "id": "P48994-1", "name": "Transient-receptor-potential-like protein", "aln": "MGRKKKLPTGVSSGVSHASSAPKSVGGCCVPLGLPQPLLLEEKKFLLAVERGDMPNVRRILQKALRHQHININCMDPLGRRALTLAIDNENLEMVELLVVMGVETKDALLHAINAEFVEAVELLLEHEELIYKEGEPYSWQKVDINTAMFAPDITPLMLAAHKNNFEILRILLDRGAAVPVPHDIRCGCEECVRLTAEDSLRHSLSRVNIYRALCSPSLICLTSNDPIITAFQLSWELRNLALTEQECKSEYMDLRRQCQKFAVDLLDQTRTSNELAIILNY--DPQMSSYEPGDRMSLTRLVQAISYKQKKFVAHSNIQQLLSSIWYDGLPGFRRKSIVDKVICIAQVAVLFPLYCLIYMCAPNCRTGQLMRKPFMKFLIHASSYLFFLFILILVSQRADDDFVRIFG--TTRMKK----ELAEQELRQRGQTPSKLELIVVMYVIGFVWEEVQEIFAVGMKSYLRNMWNFIDFLRNSLYVSVMCLRAFAYIQQATEIARDPQMAYIPREKWHDFDPQLIAEGLFAAANVFSALKLVHLFSINPHLGPLQISLGRMVIDIVKFFFIYTLVLFAFACGLNQLLWYFAALEK----SKCYVLPGGEADWGSHGDSCMKWRRFGNLFESSQSLFWASFGMVGLDDFELSGIKSYTRFWGLLMFGSYSVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKFARTKLWMSYFEDSATLPPPFNVLPSVKWVIRIFRKSSKTIDRQRSKKRK--------------------------------------------------------------------EQE-QFSEYDNIMRSLVWRYVAAMHR-KFENNPVSEDDINEVKSEINTMRYEMLEIFENSGMDVSSANKKER-QPRPRRIKVWERRLMKGFQVAPVQN--------GCELDAFG----------NVNGQGEMQEIKVESIPSKPAKETAKERFQRVARTVLLQSTTHKWNVVLRAAK------DSQIGRCTKNERK---SLQNLGRAIEEAKRLIMLN-PGCPSGRESPIRIEFEDEK----------------TSTLLELLNQISAEISDSEKP-------------------------------KIRPIWRPPLKTVP----ARAMAANNTRSLTAPELKIS--------RKSSPAPTPTPTPGVSHTALSQFRNRELPLCPSKLIAN-----SAPSAPTAPPKKSAPTAPTPT-----YKP-TTHAPFSVEGGN------------RENTRASDGVRSDNSNFDIHVVDLDEKGGHLGRDNVSDISSIASTSPQRPKHRN---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** :: : *:** ..: * : :*:** **:.* ** **:***:::: :*: .: . *****:* * * *** **: : . . . : *: ****::**** :*:**:::*:::*. :* **:::*.* *** ****** **:* *:**.:.**:.*:*.**.:***:*****:.* * * : ** :: : :.*. ***::*:* ** ::**. * ** ** :** ***:.* ****:: **: :**:**: : : :. **. .: *: ** . . :****:**: *:.**: **::* .* : .:. * :* :: :: .::: *::.:: *: .*: : **.:*:: * :*:: : : : *: *. :.* *:.*. *: . :** *:*: :*: *.******:**.**::**:**:*:* ***:**. ***** :*: . .. * .:**: *:***: **:: * :: . : :* * . ***:*.:*.::****:*****.:** * :::* ******::**:****:..* *.***: *. * . : . :::::: ** **::. * : ::*::. *::.:*.::* *:: :: .. . .. . . . : : .: . . ", "identical_positions": 244, "similar_positions": 239, "identity": "17.6%" }, { "cls_id": "homologset.agr.RGD:621277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MA2-1", "uniprot_id": "XPP2_RAT", "id": "Q99MA2-1", "name": "Xaa-Pro aminopeptidase 2", "aln": "----------------------MAQAYWQCYPWLVLLCACAWSYP-------GPESLGREDVRDCSTNPPRLP--------------------------VTAVNTTMRLAALRQQMEKSNLSAYIIPDTDAHMSEYIGKHDERRAWISGFTGSAGTAVVT-----------KKKAAVWTDSRYWTQAERQMDCNWELHKEVS-ISSIVAWILAEVPDGEN-----------VGFDPFLFSVGSWENYDQELQ-----DSNRHLLSITTNLVDVAWG--SERPPVP-SQPIYALPKEFTGSTWQEKVSAIRSYMQNHTMAPTG----VLLSALDETAWLFNLRSSDIPYNPFFYSYTLLTDSSIRLFVNKSRFSLETLQYLNTN-----------CTLPMCVQLEDYSQIRDGVKAYASGNVKILIGISYTTYG----VYDVIPKEKLVTETYSPVMLIKAVKNSKEQALLKASHVRDAVAVIQYLVWLEKNVP--KGTVDEFSGAEHIDQLRRNENFSSGPSFETISASGLNAALAHYSPTKELHRKLSLDEMYLVDSGGQYWDGTTDITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVFPAATSGRVVEAFARRALWEVGLNYGHGTGHGIGNFLCVHEWPVGFQYN----NMAMAKGMFTSIEPGYYQDGEFGIRLEDVALVVEAKTKYP--GTYLTFELVSFVPYDRNLIDVSLLSPEQLQYLNRYYQTIRENIGPELQRRQLLEEFAWLERHTEPLSASAP------HTTSLASMWVASALAILSWSC------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AVD1-1", "uniprot_id": "XPP2_MOUSE", "id": "B1AVD1-1", "name": "Xaa-Pro aminopeptidase 2", "aln": "----------------------MAQAYWQCYPWLVLLCACAWSYP-------EPKYLGREDVRNCSTSPERLP--------------------------VTAVNTTMRLAALRQQMETWNLSAYIIPDTDAHMSEYIGKPDKRREWISGFTGSAGTAVVT-----------MGKAAVWTDSRYWTQAERQMDCNWELHKEVS-ISSIVAWILAEVPDGQN-----------VGFDPFLFSVDSWKNYDQGFQ-----DSSRHLLSVTTNLVDVAWG--SERPPVP-SQPIYALPKEFTGSTWQEKVSAVRSYMEHHAKTPTG----VLLSALDETAWLFNLRSSDIPYNPFFYSYALLTNSSIRLFVNKSRFSLETLQYLNTN-----------CTLPMCVQLEDYSQVRDSVKAYASGDVKILIGVSYTTYG----VYEVIPKEKLVTDTYSPVMLIKAVKNSKEQALLKSSHVRDAVAVIQYLVWLEKNVP--KGTVDEFSGAEYIDELRRNENFSSGPSFETISASGLNAALAHYSPTKELHRKLSSDEMYLVDSGGQYWDGTTDITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVFPAATSGRVIEAFARRALWEVGLNYGHGTGHGIGNFLCVHEWPVGFQYN----NIAMAKGMFTSIEPGYYHDGEFGIRLEDVALVVEAKTKYP--GDYLTFELVSFVPYDRNLIDVRLLSPEQLQYLNRYYQTIRENVGPELQRRQLLEEFAWLEQHTEPLSARAP------HIISWTSLWVASALAILSWSS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43895-1", "uniprot_id": "XPP2_HUMAN", "id": "O43895-1", "name": "Xaa-Pro aminopeptidase 2", "aln": "----------------------MARAHWGCCPWLVLLCACAWGHT-------KPVDLGGQDVRNCSTNPPYLP--------------------------VTVVNTTMSLTALRQQMQTQNLSAYIIPGTDAHMNEYIGQHDERRAWITGFTGSAGTAVVT-----------MKKAAVWTDSRYWTQAERQMDCNWELHKEVG-TTPIVTWLLTEIPAGGR-----------VGFDPFLLSIDTWESYDLALQ-----GSNRQLVSITTNLVDLVWG--SERPPVP-NQPIYALQEAFTGSTWQEKVSGVRSQMQKHQKVPTA----VLLSALEETAWLFNLRASDIPYNPFFYSYTLLTDSSIRLFANKSRFSSETLSYLNSS-----------CTGPMCVQIEDYSQVRDSIQAYSLGDVRIWIGTSYTMYG----IYEMIPKEKLVTDTYSPVMMTKAVKNSKEQALLKASHVRDAVAVIRYLVWLEKNVP--KGTVDEFSGAEIVDKFRGEEQFSSGPSFETISASGLNAALAHYSPTKELNRKLSSDEMYLLDSGGQYWDGTTDITRTVHWGTPSAFQKEAYTRVLIGNIDLSRLIFPAATSGRMVEAFARRALWDAGLNYGHGTGHGIGNFLCVHEWPVGFQSN----NIAMAKGMFTSIEPGYYKDGEFGIRLEDVALVVEAKTKYP--GSYLTFEVVSFVPYDRNLIDVSLLSPEHLQYLNRYYQTIREKVGPELQRRQLLEEFEWLQQHTEPLAARAP------DTASWASVLVVSTLAILGWSV------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07825-1", "uniprot_id": "FRA1_YEAST", "id": "Q07825-1", "name": "Putative Xaa-Pro aminopeptidase FRA1", "aln": "MTSKPSTSDGRAHSISHVPGTHMRGTSASHSPRPFRPCADCTCSPGLLSRQGRRASLFLRQLENSRRSSSMLLNELKGAGGGSSAGNGSVYSCDSLCAVNREVNTTDRLLKLRQEMKKHDLCCYIVPSCDEHQSEYVSLRDQRRAFISGFSGSAGVACITRDLLNFNDDHPDGKSILSTDGRYFNQARQELDYNWTLLRQNEDPITWQEWCVREALEMAKGLGNKEGMVLKIGIDPKLITFNDYVSFRKMIDTKYDAKGKVELVPVEENLVDSIWPDFETLPERP-CNDLLLLKYEFHGEEFKDKKEKLLKKLNDKASSATTGRNTFIVVALDEICWLLNLRGSDIDYNPVFFSYVAINEDETILFTN-NPFNDDISEYFKINGIEVRPYEQIWEHLTKITSQASSAEHEFLIPDSASWQMVRCLNTSTNANG----AIAKKMTAQNFAIIHSPIDVLKSIKNDIEIKNAHKAQVKDAVCLVQYFAWLEQQLVGREALIDEYRAAEKLTEIRKTQRNFMGNSFETISSTGSNAAIIHYSPPVENSSMIDPTKIYLCDSGSQFLEGTTDITRTIHLTKPTKEEMDNYTLVLKGGLALERLIFPENTPGFNIDAIARQFLWSRGLDYKHGTGHGIGSFLNVHEGPMGVGFRPHLMNFPLRAGNIISNEPGYYKDGEYGIRIESDMLIKKATEK----GNFLKFENMTVVPYCRKLINTKLLNEEEKTQINEYHARVWRTIVHFLQPQ--SISYKWLKRETSPL--------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VG44-1", "uniprot_id": "Q9VG44_DROME", "id": "Q9VG44-1", "name": "Xaa-Pro aminopeptidase 2", "aln": "----------------------MTTAKWIWRLALSILLVVGFVAA-------EKPTGYHREICQYRKGKHIQP----------------------MSVYHNRLMAMREQMQIRATLQGPEIYGYILPSTDEHLNQEVAARDQRLRYLSGFSGVRAFAAVT-----------SHGAAIWVENRYAQQADGELECDWEIYLTSG-NVSVADWLGSHVHIDKR-----------VGADPHLVPHSLWVQWERELE-----DKFLKLVRINTNLVDHIWG--DERPEMPKNQVIKVHEKHFAGESWQDKVKELRRRLAHLGCDAMV------VTSLTEIAYLLNIRGTDIPYTPVIKSYAVISRDDIFFYVDHSKISLGIDLHLRTD-----------CFNEDCVKIKEYNQIWSDIRTYAQIWKRVLVPAPCVQDLGASEAIYTSMPGKIVVWEISPIIFMRAQKNSDEQAGMRRAHIRDGAAICEAMSNMETRFH--TEQWTEEKIKYEVELWRLSQKHAKGLSLRTVVAYGEHSALPYYISSNVTNIEVSDQSLLVIESGGQYLEGTTDVSRTFIFGEPTHEMKKAYTNVLAGILHLAQLKFPSDLKPSEVDALVRSMVWKDMTDFPQATGHGIGSFGSVEEPPISVSYGKN-SSFHFKQGYFFSSESGYYKRDDFGVRLKNVLEVVDTGHTHPSGARFLAFRDVTMVPYEPKLIDSTLLSAAEKRLLNEYNAKIRNDIGDELKRLGNMRAFYWMMNQTRHIREYLPEDEYRSATGAGSCGHSASPLILLGLGLMVILSAIIPSRS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . . .:: : . : : :* :: :: **:*. * * .: :. *:* :::**:* . * :* : : .:.** ** ::: :* : . * . . :* ** *.. . : .: :: .*: : **** * . * * : : * *. :::* . : : . . : :* * .:*:*:*.:** *.*.: **. :. .. ::.: . :. ::. . .. . : : : : . : .. **: . :: **. * : ::::*...: . : :* .. * : * :. * *:.*: : * ::*: :* .. :. .: : :**.*: :****::**. *: . ** ** * : * :* ** ::*:.* :*. :: :.******.* *.* *:.. .: : * : * *.***: .::*:*::. : .: . . :* *. ::.*** :**: **. . :*.* : . : *: : *: ..* : ", "identical_positions": 115, "similar_positions": 204, "identity": "14.29%" }, { "cls_id": "homologset.agr.RGD:621278", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84083-1", "uniprot_id": "ARF5_RAT", "id": "P84083-1", "name": "ADP-ribosylation factor 5", "aln": "MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P84084-1", "uniprot_id": "ARF5_MOUSE", "id": "P84084-1", "name": "ADP-ribosylation factor 5", "aln": "MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84085-1", "uniprot_id": "ARF5_HUMAN", "id": "P84085-1", "name": "ADP-ribosylation factor 5", "aln": "MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZUW4-1", "uniprot_id": "Q7ZUW4_DANRE", "id": "Q7ZUW4-1", "name": "ADP-ribosylation factor", "aln": "MGLTISSLFGRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVAESAEELSKMLQEDELRDAVLLVFANKQDLPNAMAVSELTDKLGLQSLRSRTWYVQATCATQGTGLYEGLDWLSNELSKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6P5M5-1", "uniprot_id": "Q6P5M5_DANRE", "id": "Q6P5M5-1", "name": "ADP-ribosylation factor", "aln": "MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVAESAEELSKMLQEDELRDAVLLVFANKQDLPNAMAVSELTDKLGLQSLRSRTWYVQATCATQGTGLYEGLDWLSNELSKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40945-1", "uniprot_id": "ARF4_DROME", "id": "P40945-1", "name": "ADP ribosylation factor 4", "aln": "MGLTISSLLTRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRITEAERELQNMLQEDELRDAVLLVFANKQDLPNAMTAAELTDKLRLNQLRNRHWFIQSTCATQGHGLYEGLDWLSAELAKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*:*: *:*************************************************************************************:*: *: **.:********************:****..:****** *: **.* *::*:****** ***:****** **:*:", "identical_positions": 150, "similar_positions": 21, "identity": "83.33%" }, { "cls_id": "homologset.agr.RGD:621279", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62330-1", "uniprot_id": "ARF6_HUMAN", "id": "P62330-1", "name": "ADP-ribosylation factor 6", "aln": "MG----KVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTR-IRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62332-1", "uniprot_id": "ARF6_RAT", "id": "P62332-1", "name": "ADP-ribosylation factor 6", "aln": "MG----KVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTR-IRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62331-1", "uniprot_id": "ARF6_MOUSE", "id": "P62331-1", "name": "ADP-ribosylation factor 6", "aln": "MG----KVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTR-IRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40946-1", "uniprot_id": "ARF6_DROME", "id": "P40946-1", "name": "ADP-ribosylation factor 6", "aln": "MG----KLLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARTELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTR-IRDRNWYVQPSCATSGDGLSEGLIWLTSNHKL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40994-1", "uniprot_id": "ARF3_YEAST", "id": "P40994-1", "name": "ADP-ribosylation factor 3", "aln": "MGNSISKVLGKLFGSKEMKILMLGLDKAGKTTILYKLKLNKIKTSTPTVGFNVETVTYKNVKFNMWDVGGQQRLRPLWRHYFPATTALIFVIDSSARNRMEEAKEELYSIIGEKEMENVVLLVWANKQDLKDAMKPQEVSDFLELEKNLKNQPWCVIGSNALSGQGLVEGLSWISNNTNVPKK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *:*.*:**.***:******* ************.: *: ******************:******:::*******:..* .****:*.: *:*::**: **: **.::**.:.::*::****** *****:*:.: * * : :::: * * * * **:** *** *::.* : ", "identical_positions": 105, "similar_positions": 48, "identity": "57.38%" }, { "cls_id": "homologset.agr.RGD:621280", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q924I2-1", "uniprot_id": "M4K3_RAT", "id": "Q924I2-1", "name": "Mitogen-activated protein kinase kinase kinase kinase 3", "aln": "----------MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHANIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQPLTRSLAIELLDKVNNPDHSTYHDFDDDDPEP---------------------------LVAVPHRIPS--TSRNVREEKTRSEINFG-------------QVKFDPPLRKETEP------------------------------------------------HHEL---------------------DLQLEYGQGHQSNYFLGGNKSLLKSVEEELHQR---------------------GHVAHLEDDEG-----------------DDDD----SKHSTLK---AKVP-----------------------------PPLPPKPKSISIPQDTHSS--EDSNQG------TIKRCPSSGS--------------------------------PAKPS-HVPPRPPPPRLPPQKPAVLG---NGVSSFQLNG--------ERDGSVHQQ-----------------------------QSEQRGTNLS---------------------------------------RKEK--------------------KDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCATSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSVSGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKFAVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIEFPMPCP------------LRMFEMLVVPEQEYPLVCVGVSRGRD---------FNQVVRFETVNPNSTSSWFTESDTPQTNVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDNTRIFRLLGSDRVVVLESRPTDNPTANS----NLYILAGHENSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JP0-1", "uniprot_id": "M4K3_MOUSE", "id": "Q99JP0-1", "name": "Mitogen-activated protein kinase kinase kinase kinase 3", "aln": "----------MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRPNAEKLLQHPFVTQPLTRSLAIELLDKVNNPDHSTYHDFDDDDPEP---------------------------LVAVPHRIPS--TSRNVREEKTRSEINFG-------------QVKFDPPLRKETEP------------------------------------------------HHELPDSDGFFDSSEEIYYTARSNLDLQLEYGQGHQSHCFLGGNKSLLKSVEEELHQR---------------------GHVAHLEDDEG-----------------DDDD----SKHSTMK---AKVP-----------------------------PPLPPKPKSIFIPQDTHSA--EDGNQG------TIKRCPSSGS--------------------------------PAKPS-HVPPRPPPPRLPPQKPAVLG---NGVNSFQLNG--------ERDGSLYQQ-----------------------------QSEQRGTNLS---------------------------------------RKEK--------------------KDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCATSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSVSGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKFAVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIEFPMPCP------------LRMFEMLVVPEQEYPLVCVGVSRGRD---------FNQVVRFETVNPNSTSSWFTESDAPQTSVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDNTRIFRLLGSDRVVVLESRPTDNPTANS----NLYILAGHENSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVH8-1", "uniprot_id": "M4K3_HUMAN", "id": "Q8IVH8-1", "name": "Mitogen-activated protein kinase kinase kinase kinase 3", "aln": "----------MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQHLTRSLAIELLDKVNNPDHSTYHDFDDDDPEP---------------------------LVAVPHRIHS--TSRNVREEKTRSEITFG-------------QVKFDPPLRKETEP------------------------------------------------HHELPDSDGFLDSSEEIYYTARSNLDLQLEYGQGHQGGYFLGANKSLLKSVEEELHQR---------------------GHVAHLEDDEG-----------------DDDE----SKHSTLK---AKIP-----------------------------PPLPPKPKSIFIPQEMHST--EDENQG------TIKRCPMSGS--------------------------------PAKPS-QVPPRPPPPRLPPHKPVALG---NGMSSFQLNG--------ERDGSLCQQ-----------------------------QNEHRGTNLS---------------------------------------RKEK--------------------KDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCASSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSISGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKFSVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIDFPIPCP------------LRMFEMLVVPEQEYPLVCVGVSRGRD---------FNQVVRFETVNPNSTSSWFTESDTPQTNVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDSTRIFRLLGSDRVVVLESRPTDNPTANS----NLYILAGHENSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJU9-1", "uniprot_id": "A0A8M3AJU9_DANRE", "id": "A0A8M3AJU9-1", "name": "Mitogen-activated protein kinase kinase kinase kinase", "aln": "----------MNLSLDLSRRNPQEDFELIQRIGSGTYGDVYKARNVSTGELAAIKVIKLEPGEDFDVVQQEIIMMKDCKHSNIVAYFGSYLRRDKLWISMEYCGGGSLQDIYHVTGPLSESQIAYVCRETLQGVYYLHNKGKIHRDIKGANILLTDNGYVKLADFGVSAQISATLAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELEPPMFDLHPMRALFLMTKSSFQPPKLKDKVKWTNNFHHFVKMALTKNPKKRPTADRLLQHPFVTQPLSRTLAIELLDKANNPDHSTHSDAEEDDIDP-------------------------ESPVSVPHRIRS--TSRSSRDGKTLSEINFD-------------KVKFDPPLRKETEP------------------------------------------------HHE---------------------MDLPLEPQ------SILGNNKSLLKSVAEELNQR---------------------GHVTHLEDEEE-----------------DEGDDLHCNSTSTMR---PKVP-----------------------------PPLPPKPK-VLSPAQSSSASEDNNGEG------TIKRCPASASST-----------------------------PPARPASCVPPRPPPPRLPPHRRSSLG--KKPSEHAQTEP--------TGDDGIY-----RFWEWLHAEE-----------------QEEHSNGVS---------------------------------------SPEN-GDKEKLASLPSCS--------LQLPFSNGLPPTPKVHMGACFSKVFNGCPLKIHCACSWINPNTRDQYLIFGAEEGIYTLNLNEIHESTMEQLVPRRCTWVYVMNNWLLSISGKASQLYSYNLTGLFEQARQMQKLPVAIPTHKLPDKIIPRKFTVSNKIPETRGCQKCCVVRNPYTGHKYLCGAFQSSVMLFEWVEAMQRFMLIKSIELTLPCP------------LEVFEMLVVPEQHYPVVCVAVSKGSH---------PDQVVTFGTVDPNAGNPTFTEPETPQTCVIHVTQLERDTVLVCLDRCIKLVNLQGRLKSNKKLSTELTFNFQIEAIVCLQDSVLAFWKHGMQGRSFKNSEITQEISDNSRTYRLLGADRVVVLESKPTEDPTAQS----NLYILAGHENSY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32U0S1-1", "uniprot_id": "A0AB32U0S1_DANRE", "id": "A0AB32U0S1-1", "name": "Mitogen-activated protein kinase kinase kinase kinase", "aln": "----------MNSSFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVTTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHSNIVAYFGSYLRRDKLWISMEYCGGGSLQDIYHVTGPLTESQIAYVTRETLQGLYYLHNKGKMHRDIKGANILLTDNGYVKLADFGVSAQITATLAKRKSFIGTPYWMAPEVAAVERKGGYNHLCDIWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKVKWTNNFHNFVKLALTKNPKKRPPADKLLQHPLVSQPLSRILAIELLDKANNPDHSSYTDLDDDDPEPEFKYRGLFLPVSPLSRRVLRFAARRKPPVSVPHRIRS--TSRTSREGKTLSEINFG-------------QVKFDPPLTTETKP------------------------------------------------HHEQLDTDDFLDCAEEIYYTARSNLDLQMDYEQGSPKGSILGGNKSLLKSVEEELQQR---------------------GHEAHLEDDDEG-----------EDDGDDHDDELQHTKSSTMR---PKVP-----------------------------PPLPPKPKPSPGPHQSPSADPDRNNQG------TIKRCPEPES--------------------------------PARSSTSVPPRPPPPRLPAYKLSSLGNETHQEEHGLWGA--------QGDAGICSQFDQRLQVSFDDEEN--------------HDEEENSNGIS---------------------------------------PSEHSASTERQSTMPPAVPVPKDKKDFPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCATSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLVPRRCTWLYVLSNSLLSISGKACHLYSHSLSGLFEHARQMQKLPVSIPTHKLPDKMIPRKFSVSNKIPETKGCQKCCVVRNPYTGHKYLCGAFQSSIALFEWVETMQKFMLVKSIDFPLPCP------------LEVFEMLVVPEHQYPLICIAVSKGTE---------LNQVVRFETLNPNS-TSNWFDSDTPQSCVIHVTQLERDTILVCLDRCIKIVNLQGRLKSSRKLSAELTFNFQIESIVCLQDSVLAFWRHGMQGRSFKSNEITQEISDNSRIFRLLGSDRVVVLESRPTDNPTAHS----NLYILAGHENSY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBH7-1", "uniprot_id": "A1ZBH7_DROME", "id": "A1ZBH7-1", "name": "non-specific serine/threonine protein kinase", "aln": "MAAAHSHHNANMLSSDISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFVQCEMSLRVAKELLQKYQSPNPQFYYYLDGDEESVAG----------VPQRIASKMTSRTNGVPAQNHTLKTGMTTNSTWNERSSSPETLPSDMSLLQYIDEELKLRATLPLNNDTKDPLGAECSCSSHNGGAAGGGGGGGVGVGAGGAAANGSSSSSGGATVGTTHHQHQQHHQHHHHPNHLHQHQSHQLPQQQQQQSHQAAQQEHHHHHPMTSSISSGLVTANANNISSSASLASMPGLSAYLGMRSHVVGHMGMGFGMGLGMSNLRTTSIDADDDELVAADVAMNNAAAAVPGNGSGAGNGSGSGCSASAAHYLRYSSNYRSAAAAQASQAAHPHVNSNSN-SNNGHGHAPITSSISSSASSASFYNRLLLLDNSSGDAVVGGNGGGSSNISSSGGASSGTNGLLDKHELDALPQAATKSAGDGFSHSNSPTANSGAGATGSRDNDGPSSSNSSHLYQNLLRSSSGETPAGSSSAGNNCDYRHENNQNGLEDSPRRHSSMDQLIGLLENMGKSPRTRSLSDGGTQDDDEAEKEAQPDLLNNTPPVPPKRSHKRRHTPPRPISNGLPPTPKVHMGACFSKIFNGCPLRVHCTASWIHPETRDQHLLIGAEEGIYNLNMNELHDAAIDQLFPRRTTWLYVIKDVLMSLSGKSCQLYRHDLVALHS----KQTVRFSLHMNKIPERLVPRKFALTTKVPDTKCCTQCCVTRNPYNGYKYLCGATPSGIFLMQWYDPLNKFMLLKQCEWPAISIQGGGHGCVQNGHTPVFEMIITPELEYPIVCTGVRKAMNGCLKLELINMNSASWFHSEDLEYDAMATMVPRRDLLKVVRVHQVEKDAILVCYGNLIQVVTLQGNPKQHKKMVSQLNFDFNVDSIVCLPDSVLAFHKHGMQGKSLRNGEVTQEIKDMSRTYRLLGSDKVVALESQLLRTGSLGSEEGHDLYILAGHEASY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:******:::****:************:.: :.************.:*: ::*******:**:*.**:**:***********.**:**********:*****:* ****: ****:*: ***. **:************: * ************:**: **************************:***:** **********:***************:**.*:**.*::* **: .**:*:* ********** *::*****:* :: :* ***:* :.*: . : : *: . : * : : *:.. : :: * .: ::: ** .:*: **: : ::.: .*: . * * :*: .. * .: ::. . :* .. ..:.. * .: . ..* :*. .. . * .: : : : ** * . * *.. ..:. * *:******************:******::**: ***:*:****:*::*******.**:**:*:::::**.*** **:**:.: *:*:***:.:** :.* .*.. *.: .:: :*:*::::****::: *:*:*: * :***.****.*:****** :.: *::* :.:::***:* : . . :***::.** .**::* .* :. . :.. * : : : . * :* *:*:*::*** . *::*.***. *. :*: ::*.*:*::::**** ****** :*****:*::..*:****.* :* :****:*:**.***: : * :******** **", "identical_positions": 406, "similar_positions": 250, "identity": "32.93%" }, { "cls_id": "homologset.agr.RGD:621281", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R915-1", "uniprot_id": "M0R915_RAT", "id": "M0R915-1", "name": "", "aln": "MAAQGEAFEERICEFDDDLVSEFSTLLRVDALQVLKRQQEEDHKTRMKMKKGFNAQMRSEAKRLKTFVTYDTFRSWTPQEMAAAGFYYTGVRHGVQCFCCSLILFATRLRKVPIEVHRKLQPECEFLSGKDVGNIGKYDIRVKSPETLPRGGRARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSAEEIAKYIQTYEGFLHVTGEHFVNSWVRRELPVVSAYSNDSVFANEGLRMDTFKDWPHESPMAVEALVKAGLFYTGKKDIVQCFSCGGCMENWKEGDDPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCARPEAMETTSESNHEDGVAVHSSVAGIP---------------------------------TCTSLPSADLGQSEAQWCQEARSLSEQLRGTYTKASFRHMNLPEAYSSLGTDHLLGCEVFLISKHVSRPVQVALTIPEVFANLSSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLNRFQLVFYLSLRSIRADQGLADIICAQLLEAGGCISEVSLSSGIQHLQHQVLFLLDDYSGMDSLPQALDTLITKNYLSRTCLLMAVHTNRVRDIRPYLETVLQIKEFPFYNTVYILKKIFSHDIIRVRRFINYFGFHEYLQGIHKTPLFVAGVCADWLQNPSDQPFQDVTIFKSYMQYLFLKHKATAGPLQATVSSCGHLALTGLFSSSFEFSSDDLIEAGVDEDEELSTCLMSKFTAQRLRPVYRFLSPLFQEFLAAMRLSELLGSDSQEDQDLGLYYLRQINSPLKAMSIYHTFLRYVSNHPSSKAGPKVISHLLQLVDEKESPENTSENEDYMKLHPETLLWSQCLRGLLQLSPESFSLFISERLLNIALNFAYQSNTVAACSPVILQFLQGRTLDLKVLNLQYFWDHPETLLLLKSIQVLFNGNNRVQRIDFSLMDKSFEKIQPPTIDQDYAFAFQPMSECQRNLAEKENIIKNYDDMKYQDPLNISSGYWKLSPKPYKIPRLEVGVNNMGPADQALLHVLMEVFSASQSIEFHLFNSSGFLESIRPALELNKTSVTKCSMSRLELSRAEQELLLTLPALQSLEVSGTSQIPDQLFHNLDKFLGLKELSVRLDGTQDMLSVLPGEFPNLHHMEKLSIHTSTESDLSKLVKLIQNSPNLHDFHLKCDFLSNCESLMAALASCKKLREIEFSGRCFEAVPFVNILSNFASLKILNLRNQQFPDKETSEKFAQALGSLRNLEELHLPTGDGIHQVAKPIVRRCLQLPCLRVLVFAETLDDDSVLEIAKGATSGGFQNLENLDLTLNHKITEEGYRNFFQALDNLPNLQNLDISRHIPECIQVQASTVKALGQCVSRLPSLTRLGMLSWLLDEEDMKVINDVKERHPQSKRLTVHWRWVVPFSPVIQK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUK4-1", "uniprot_id": "BIR1B_MOUSE", "id": "Q9QUK4-1", "name": "Baculoviral IAP repeat-containing protein 1b", "aln": "MAAQGEAVEEIICEFDDDLVSELSTLLRVDALSVLKRQQEEDHKTRMKMKKGFNSQMRSEAKRLKTFETYDKFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFSTRLRKLPIENHKKLRPECEFLLGKDVGNIGKYDIRVKSPEKMLRGDKARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSPEEITQYVQSYEGFLHVTGEHFVNSWVRRELPMVSAYCNDSVFANEELRMDTFKDWPHESPGAVEALVKAGLFYTGKRDIVQCFSCGGCMEKWAEGDNPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCALPEAMETTSESNHDDAAAVHSTVVDVSPSEAQELEPASSLVSVLCRDQDHSEAQGRGCASSGTYLPSTDLGQSEAQWLQEARSLSEQLRDTYTKATFRHMNLPEVYSSLGTDHLLSCDVSIISKHISQPVQGSLTIPEVFSNLNSVMCVEGEAGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPGQELAKIICAQLLGAGGCISEVCLSSIIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLSRTCLLIAVHTNKVRGIRPYLDTSLEIKEFPFYNTVSVLRKLFSHDIMRVRKFINYFGFHEELQGIHKTPLFVAAVCTDWFKNPSDQPFQDVALFKAYMQYLSLKHKGAAKPLQATVSSCGQLALTGLFSSCFEFNSDNLAEAGVDEDEELTTCLMSKFTAQRLRPVYRFLGPLFQEFLAAVRLTELLSSDRQEDQDLGLYYLRQINSPLKAMSIYHTFLKYVSSHPSSKAAPTVVSHLLQLVDEKESLENMSENEDYMKLHPEALLWIECLRGLWQLSPESFSLFISENLLRICLNFAHESNTVAACSPVILQFLRGRTLDLKVLSLQYFWDHPETLLLLKSIKISLNGNNWVQRIDFSLIEKSFEKVQPPTIDQDYAIAFQPINEVQKNLSEKKHIIKKYEDMKHQIPLNISTGYWKLSPKPYKIPKLEVQVTNTGPADQALLQVLMEVFSASQSIEFRLSDSSGFLESIRPALELSKASVTKCSMSRLELSREDQKLLLTLPTLQSLEVSETNQLPDQLFHNLHKFLGLKELCVRLDSKPDVLSVLPGEFPNLHHMEKLSIRTSTESDLSKLVKLIQNSPNLHVFHLKCNFLSNCEPLMTVLASCKKLREIEFSGRCFEAMTFVNILPNFVFLKILNLRDQQFPDKETSEKFAQALGSLRNLEKLFVPTGDGIHQVAKLIVRQCLQLPCLRVLVFAETLDDDSVLEIAKGATRGGFQKLENLDLTLNHKITEEGYRNFFQVLDNLPNLKNLDISRHIPECIQIQAITVKALGQCVSRLPSLTRLGMLSWLLDEEDIKVINDVKERHPQSKRLTVHWRWVVPFSPVIQK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13075-1", "uniprot_id": "BIRC1_HUMAN", "id": "Q13075-1", "name": "Baculoviral IAP repeat-containing protein 1", "aln": "MATQQKASDERISQFDHNLLPELSALLGLDAVQLAKELEEEEQKERAKMQKGYNSQMRSEAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKRFHPDCGFLLNKDVGNIAKYDIRVKNLKSRLRGGKMRYQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSEEITQYIQSYKGFVDITGEHFVNSWVQRELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDDHTRCFPNCPFLQNMKSSAEVTPDLQSRGELCELLETTSESNLEDSIAVGPIVPEMA--------------------------------------------QGEAQWFQEAKNLNEQLRAAYTSASFRHMSLLDISSDLATDHLLGCDLSIASKHISKPVQEPLVLPEVFGNLNSVMCVEGEAGSGKTVLLKKIAFLWASGCCPLLNRFQLVFYLSLSSTRPDEGLASIICDQLLEKEGSVTEMCVRNIIQQLKNQVLFLLDDYKEICSIPQVIGKLIQKNHLSRTCLLIAVRTNRARDIRRYLETILEIKAFPFYNTVCILRKLFSHNMTRLRKFMVYFGKNQSLQKIQKTPLFVAAICAHWFQYPFDPSFDDVAVFKSYMERLSLRNKATAEILKATVSSCGELALKGFFSCCFEFNDDDLAEAGVDEDEDLTMCLMSKFTAQRLRPFYRFLSPAFQEFLAGMRLIELLDSDRQEHQDLGLYHLKQINSPMMTVSAYNNFLNYVSSLPSTKAGPKIVSHLLHLVDNKESLENISENDDYLKHQPEISLQMQLLRGLWQICPQAYFSMVSEHLLVLALKTAYQSNTVAACSPFVLQFLQGRTLTLGALNLQYFFDHPESLSLLRSIHFPIRGNKTSPRAHFSVLETCFDKSQVPTIDQDYASAFEPMNEWERNLAEKEDNVKSYMDMQRRASPDLSTGYWKLSPKQYKIPCLEVDVNDIDVVGQDMLEILMTVFSASQRIELHLNHSRGFIESIRPALELSKASVTKCSISKLELSAAEQELLLTLPSLESLEVSGTIQSQDQIFPNLDKFLCLKELSVDLEGNINVFSVIPEEFPNFHHMEKLLIQISAEYDPSKLVKLIQNSPNLHVFHLKCNFFSDFGSLMTMLVSCKKLTEIKFSDSFFQAVPFVASLPNFISLKILNLEGQQFPDEETSEKFAYILGSLSNLEELILPTGDGIYRVAKLIIQQCQQLHCLRVLSFFKTLNDDSVVEIAKVAISGGFQKLENLKLSINHKITEEGYRNFFQALDNMPNLQELDISRHFTECIKAQATTVKSLSQCVLRLPRLIRLNMLSWLLDADDIALLNVMKERHPQSKYLTILQKWILPFSPIIQK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* :* :* *.:**.:*:.*:*:** :**:.: *. :**::* * **:**:*:************ **: : ** **********.***: *:**********.: * ::*** *::::*:* ** .******.*******. :. **.: **:****** **.:****.:* ** *** ********:***********************************:****.***::*:*:*:**:.:**********:****:.***.***:** * **:*:*****:**. .* **.******** :***********:*:* ***:*::***: **** ***.:****** * ***: * :******* :*. ** . * :. *.**** ***:.*.**** :**.*:****.* : *.*.*****.*:: : ***:*:*** .*.:****.**.**************.:**:************* ********** * ..: **.*** *** *.::*:.: . **:*::*********. : *:**.: .** **:*******:**:**:.*.** **:* *:** ******* :*:*:***:: *:*:*: *** :: ** *:*******.:*:.*:: * * .*:**::**:**: * *::*.:* *:*******.***.*:**..***..*:* ********:*: *************.****.* ******.:** ***.** **.******:*:*****: ::* *:.**.***. **:**.*.::****:***:*** ** ***:**:* :** * : **** *:.*::: ::**.** :.*: *::*********.:****:**** * .*.****:****:* **:**:. :.**: * .**:::..*:* * ******** **:*:.* ::**:**:. :*.* **: : . ::*:******** **** *** *.: . ..* :*.:** ****** **::* .* **:*********.*:******:*:**** :*:******:*:***** * * **:* **.*** ****.* *:.. :::**:* ****:****** *: *:* * ************** *****:*:*: .**: *.***** **:**. *:*:.** *.** ******..*****:******* **** ***:* :******::*** *:::* ** ***** * :**:****:**** * ****:****.*::**************.***:***::******:.***: ** ***:*.*** *** * **.******* :*: ::* :******** **: :*::****:***", "identical_positions": 886, "similar_positions": 334, "identity": "61.23%" }, { "cls_id": "homologset.agr.RGD:621282", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTI9-1", "uniprot_id": "A0A0G2JTI9_RAT", "id": "A0A0G2JTI9-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MAKQWGISLVVKLTKSHEQNYLPGERLLPSPPCRLTMNMVQGSAFLAKLMKSADTFELKYDFSCELYRLSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFSCGLMLDNWKQGDSPIEKHRKLYPSCSFVQTLNPANSLEASPQPPLPSTATSTMPSGFAASESTGYFSGSYSSFPSDPVNFRANQDCPAFSTSPYHFAMNTEKARLLTYQTWPLSFLSPAELAKAGFYYTGPGDRVACFACGGKLSNWDRKDDPLSEHRRHFPSCPFLKD--VGQFTSQYTVSNLSMQTH-----------AARVRTFSTWPSSALVHPQELASAGFYYTGHSDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEYLIRIKGQEFVGQVQAGYPHLLEQLLSTSDSPEDETGEAAIVHLGPGE-NWEDAVMMNTPVVKAALDMGFSRSLVRQTVQRQILATGENYRTVSDLVIGLLDAEDEMREEQTEQEAEEEESDDLTLIRKNKMVLLQHLTPVTPILDCLLSARVITEQEYDAVKQKPHT-LQARTLIDTVLAKGNTAATSFRNSLQEIDPGLYRDIFVRQNIRSLPTDDIAALPMEEQLRKLQEERTCKVCMDREVSLVFIPCGHLVVCKECAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08863-1", "uniprot_id": "BIRC3_MOUSE", "id": "O08863-1", "name": "Baculoviral IAP repeat-containing protein 3", "aln": "--------------------------------------MVQDSAFLAKLMKSADTFELKYDFSCELYRLSTYSAFPRGVPVSERSLARAGFYYTGANDKVKCFCCGLMLDNWKQGDSPMEKHRKLYPSCNFVQTLNPANSLEASPRPSLPSTAMSTMPLSFASSENTGYFSGSYSSFPSDPVNFRANQDCPALSTSPYHFAMNTEKARLLTYETWPLSFLSPAKLAKAGFYYIGPGDRVACFACDGKLSNWERKDDAMSEHQRHFPSCPFLKD--LGQSASRYTVSNLSMQTH-----------AARIRTFSNWPSSALVHSQELASAGFYYTGHSDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEYLLRIKGQEFVSQVQAGYPHLLEQLLSTSDSPEDENADAAIVHFGPGE-SSEDVVMMSTPVVKAALEMGFSRSLVRQTVQWQILATGENYRTVSDLVIGLLDAEDEMREEQMEQAAEEEESDDLALIRKNKMVLFQHLTCVTPMLYCLLSARAITEQECNAVKQKPHT-LQASTLIDTVLAKGNTAATSFRNSLREIDPALYRDIFVQQDIRSLPTDDIAALPMEEQLRKLQEERMCKVCMDREVSIVFIPCGHLVVCKDCAPSLRKCPICRGTIKGTVRTFLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13489-1", "uniprot_id": "BIRC3_HUMAN", "id": "Q13489-1", "name": "Baculoviral IAP repeat-containing protein 3", "aln": "------------------------------------MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWPLTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIEN--QLQDTSRYTVSNLSMQTH-----------AARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESSIIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESNDLLLIRKNRMALFQHLTCVIPILDSLLTAGIINEQEHDVIKQKTQTSLQARELIDTILVKGNIAATVFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVSDLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVRTFLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24307-1", "uniprot_id": "DIAP2_DROME", "id": "Q24307-1", "name": "Death-associated inhibitor of apoptosis 2", "aln": "--------------------------------------------------------MTELGMELESVRLATFGEWPLNAPVSAEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAERHRRSSPICSMVLAPNHCGNVPRSQESDNEGNSVVDSPESCSCP------------------------------------DLLLEANRLVTFKDWPNPNITPQALAKAGFYYLNRLDHVKCVWCNGVIAKWEKNDNAFEEHKRFFPQCPRVQMGPLIEFATGKNLDELGIQPTTLPLRPKYACVDARLRTFTDWPISNIQPASALAQAGLYYQKIGDQVRCFHCNIGLRSWQKEDEPWFEHAKWSPKCQFVLLAKGPAYVSEVLATTAANASSQPATAPAP-----------------TLQADVLMDEAPAKEALALGIDGGVVRNAIQRKLLSSGCAFSTLDELLHDIFDDAGAGAALEVREPPEPSAP----FIEPCQATTSKAASVPIPVADSIPAKPQAAEAVANISK------------ITDEIQKMSVATPNGN------------------------------LSLEEENRQLKDARLCKVCLDEEVGVVFLPCGHLATCNQCAPSVANCPMCRADIKGFVRTFLS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q24306-1", "uniprot_id": "DIAP1_DROME", "id": "Q24306-1", "name": "Death-associated inhibitor of apoptosis 1", "aln": "---------------------MASVVADLPSYGPIAFDQVDNNTNATQLFKNNINKTRMNDLNREETRLKTFTDWPLDW-LDKRQLAQTGMYFTHAGDKVKCFFCGVEIGCWEQEDQPVPEHQRWSPNCPLLRRR-TTNNVPIN-AEALDRILPPISYDICGAN----------------------------------------DSTLEMREHAYAEGVIPMSQLIQS----IGMNAVNAAGSVTGTAAPQPRVTVATHASTATQATGDVQPETCRPSAASGNYFPQYPEYAIE----------TARLRTFEAWPRNLKQKPHQLAEAGFFYTGVGDRVRCFSCGGGLMDWNDNDEPWEQHALWLSQCRFVKLMKGQLYIDTVAAKPVLAEEKEESSSIGG-----------------------------------------------------------------VAVASTQASEEEQQTSLSSEEAVSGDVAPSVAPTAATRIFNKIVEATAVATPSTNSSG------------------------------------------------------------------------STSIPEEKLCKICYGAEYNTAFLPCGHVVACAKCASSVTKCPLCRKPFTDVMRVYFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. * *: *: :* . :. ..*. *:: * :.:*. * : :. *: *. .*:: * * :: ..: . : : . :. :. * :: . . * : . . . :: . : . **.:** ** . . **.**::* .* *:** *. ** *:. *:** :** * .:*.:: ** :: * * .. ::: . : . : .* . . . . . : : : : **:* . * . .*:****:..* .**.*: :**:** :.. :*.::*", "identical_positions": 66, "similar_positions": 112, "identity": "10.11%" }, { "cls_id": "homologset.agr.RGD:621283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Q4-1", "uniprot_id": "METH_RAT", "id": "Q9Z2Q4-1", "name": "Methionine synthase", "aln": "-------------MKKTLQDEIEAILRKRIMVLDGGMGTMIQRYKLSEENFQGQEFKDHSRPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNKCSADVARKAAEEITLQTGVKRFVAGSLGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQKLFEENYASPRPIFISGTIVDKSGRTLSGQTGEAFVTSVSHSDP-LCIGLNCALGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDETPAMMAMHLKDFAVDGLVNVVGGCCGSTPDHIREIAEAVKNCKPRVPPDSVFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSKKFAKLIMAGNYEEALSVAKVQVEMGAQVLDINMDDGMLDGPSAMTKFCNFIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEEDFLEKARKIKKFGAAVVVMAFDEEGQATETDVKVSVCTRAYHLLVEKVGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATRVIKETLPGVRISGGLSNLSFAFRGMDAIREAMHGVFLYHAIKFGMDMGIVNAGSLPVYDDIHKDLLQLCEDLIWNRDAEATEKLLRYAQTHGKGGKKVIQTDEWRNGSIEERLEYALVKGIEKHIVEDTEEARLNREKYPRPLNIIEGPLMNGMKVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREEARVLNGSVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILQAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDDYFEEILEEYEDIRQDHYESLKERKYLPLSQARKHSFHIDWLSEPHPVKPTFIGTQVFEDYNLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKAVGEEARKVYEDAQNMLSILISRKKLRARGVVGFWPAQSVQDDIHLYAEGAVPQAAEPIATFYGLRQQAEKDSSSTDPYHCLSDFVAPLHSGVRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLGVTDLRKLRYEGIRPAPGYPSQPDHTEKLTMWRLANIEQATGIRLTESLAMAPASAVSGLYFSNVKSKYFAVGKISKDQIEDYALRKNMSVAEVEKWLGPILGYDTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6H5Y3-1", "uniprot_id": "METH_MOUSE", "id": "A6H5Y3-1", "name": "Methionine synthase", "aln": "-------------MKKTLQDEIEAILRKRIMVLDGGMGTMIQRYKLSEEHFQGQEFKDHSRPLKGNNDILSITQPDIIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNKCSADVARKAAEEITLQTGVKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVDAYQEQAKGLLDGRVDILLIETIFDTANAKAALFAIQNLFEENYAPPRPIFISGTIVDKSGRTLSGQTGEAFVTSVSHSDP-LCIGLNCSLGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDETPSTMATHLKDFAVDGLVNIVGGCCGSTPDHIREIAEAVKKCKPRVPPASVFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALSIAKAQVEMGAQVLDINMDDGMLDGPSAMTRFCNSIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEGDFLEKARKIKKFGAAVVVMAFDEEGQATETDVKVNVCTRAYHLLVDKVGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATRVIKETLPGVRISGGLSNLSFSFRGMEAIREAMHGVFLYHAIKFGMDMGIVNAGNLPVYDAIHKDLLQLCEDLIWNKDSEATEKLLRYAQTHGTGGKKVIQTDEWRNGSIEERLEYALVKGIEKHIVEDTEEARLNGEKYPRPLNIIEGPLMNGMKVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREEARLINGSVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLACNNFRVIDLGVMTPCDKILQAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLRDDYFEEILEEYEDIRQDHYESLKERKYVPLSQARKHGFHIDWLSEPHPVKPTFIGTQVFEDYNLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKAVGEEARKVYNDAQNMLNILISQKKLQARGVVGFWPAQSVQDDIHLYAEGVVPQAAEPIATFYGLRQQAEKDSSSTDPYHCLSDFIAPLHSGVCDYLGLFAVACFGVEELSKTYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYSRSEQLGVPDLRRLRYEGIRPAPGYPSQPDHTEKLTMWRLASIEQATGIRLTESLAMAPASAVSGLYFSNVKAKYFAVGKISKDQTEDYALRKNMPVAEVEKWLGPILGYDTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99707-1", "uniprot_id": "METH_HUMAN", "id": "Q99707-1", "name": "Methionine synthase", "aln": "MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAP-RPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEP-LCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQATETDTKIRVCTRAYHLLVKKLGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATKVIKETLPGARISGGLSNLSFSFRGMEAIREAMHGVFLYHAIKSGMDMGIVNAGNLPVYDDIHKELLQLCEDLIWNKDPEATEKLLRYAQTQGTGGKKVIQTDEWRNGPVEERLEYALVKGIEKHIIEDTEEARLNQKKYPRPLNIIEGPLMNGMKIVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREETRVLNGTVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIRIPLLIGGATTSKTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDEYFEEIMEEYEDIRQDHYESLKERRYLPLSQARKSGFQMDWLSEPHPVKPTFIGTQVFEDYDLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKTVGGEARKVYDDAHNMLNTLISQKKLRARGVVGFWPAQSIQDDIHLYAEAAVPQAAEPIATFYGLRQQAEKDSASTEPYYCLSDFIAPLHSGIRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLDVADLRRLRYKGIRPAPGYPSQPDHTEKLTMWRLADIEQSTGIRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQVEDYALRKNISVAEVEKWLGPILGYDTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ32-1", "uniprot_id": "Q9VJ32_DROME", "id": "Q9VJ32-1", "name": "Hcy-binding domain-containing protein", "aln": "----------------MGLTR--------VLVKDGGFGTQMTVH--VGDSVDGD-------PLWSAR--FNATNPAAIISTHLDFLQNGADIILTNTYQSSVDGYMEY-------------LELDEEQSIELIKNT-------VRLAHIAKERYLTECYQAQLSVQEGYPLIIASIGPFGAHLHDG-------------------------------------------SEYTGSYADFVPAKEITDWHRVRIE-ACLEAGVDALAIETIPCQMEAEALVEMLCDDYPDVKFWVAFQCKDENTLAHGETFADAANA----------------IWDLLAERNAQDKCLAIG--------VNCVHPKFVTPLFKSLNG----DREVGEQIPLVVYPN---------------SGEVYDVVNG---WQGREHCVPLANYVP-----------------EWAQLGAKVIGGCCRTYARDIRHIG-EAIRDWNKLKKLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ31-1", "uniprot_id": "BHMT_DROME", "id": "Q9VJ31-1", "name": "Betaine-homocysteine S-methyltransferase", "aln": "----------------MEVNQKWNWDTKPILVKCGGFSSQLAKN--VTEKVDGD-------PLWGSR--FDATNPEAVIQTHLDFLRNGADIILTNTYQSSVEGFVKY-------------LGVTRERGVELIQKS-------VQLAKQAKEQYLSEIGS---EAESALPLIMGSIGPYGAYLHDG-------------------------------------------SEYTGNYADKMSKEELRAWHKTRIE-ICLAAGVDGLALETLPCLMEAEAVTELVLDNFPDAKFWVSLQCMDEKHMASGENFAEAALS----------------LWRLVQSRKAENRLLGIG--------LNCVNPLFVTPLLSSLT-----KVAGSDRIPLVVYSN---------------RGEIYDVEQGD--WTG--TGEEVVKFVP-----------------EWIQLGVRIVGGCCRVYPTDVLAIR-KYVDGLN-IKP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12525-1", "uniprot_id": "MHT1_YEAST", "id": "Q12525-1", "name": "Homocysteine S-methyltransferase 1", "aln": "-------------MKRIPIKELIVEHPGKVLILDGGQGTELENRGININSPVWSAAPFTSESFWEPS----SQERKVVEEMYRDFMIAGANILMTITYQANFQSISEN----------------------------------TSIKTLAAYKRFLDKIVSFTREFIGEERYLIGSIGPWAAHVSCE---------------------------------------------YTGDYGPHPENIDYYGFFKPQLENFNQNRDIDLIGFETIPNFHELKAILSWDEDIISKP-FYIGLSVDDNSLLRDGTTLEEISVH----------------IKGLGNKINKNLLLMG----------VNCVSFNQSALILKMLH-------EHLPGMPLLVYPN---------------SGEIYNPKEKT--WHRPTNKLDDWETTVK----------------KFVDNGARIIGGCCRTSPKDIAEIASAVDKYS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::: ** .: : : . .: : : . : ::: **:*: * *:.:. . . : . :: : . : :* . . * * .. : : *:. . : : : : : : : :. : . : :. :: .. .:: : : : * : * * . . .: ", "identical_positions": 14, "similar_positions": 72, "identity": "1.1%" }, { "cls_id": "homologset.agr.RGD:621284", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62487-1", "uniprot_id": "RPB7_HUMAN", "id": "P62487-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGA--GVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62488-1", "uniprot_id": "RPB7_MOUSE", "id": "P62488-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGA--GVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62489-1", "uniprot_id": "RPB7_RAT", "id": "P62489-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGA--GVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7ZW41-1", "uniprot_id": "RPB7_DANRE", "id": "Q7ZW41-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGA--GVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTVDEDVVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFB5-1", "uniprot_id": "Q9VFB5_DROME", "id": "Q9VFB5-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFYHISLEQEILLHPRYFGPQLLETVKQKLYSEVEGTCTGKYGFVIAVTTIDQIGS--GVIQPGQGFVVYPVKYKAIVFRPFKGEVLDAVVKQINKVGMFAEIGPLSCFISHHSIPADMQFCPNGNPPCYKSKDEDVVISGEDKIRLKIVGTRVDATGIFAIGTLMDDYLGLVSN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34087-1", "uniprot_id": "RPB7_YEAST", "id": "P34087-1", "name": "DNA-directed RNA polymerase II subunit RPB7", "aln": "MFFIKDLSLNITLHPSFFGPRMKQYLKTKLLEEVEGSCTGKFGYILCVLDYDNIDIQRGRILPTDGSAEFNVKYRAVVFKPFKGEVVDGTVVSCSQHGFEVQVGPMKVFVTKHLMPQDLTFNAGSNPPSYQSSED--VITIKSRIRVKIEGCISQVSSIHAIGSIKEDYLGAI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: .*. :* *** :***.: : :* ** ****:****:*:::.* *:*. * * * * . : ***:*:**:******:*..* . .: *: .::**:. *:::* :* :: * ...***.*:: :: ** ...**:** * : ..*.***:: :**** : ", "identical_positions": 69, "similar_positions": 60, "identity": "39.43%" }, { "cls_id": "homologset.agr.RGD:621285", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EST6-1", "uniprot_id": "AN32B_RAT", "id": "Q9EST6-1", "name": "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "aln": "MDMKRRIHLELRNRTPAAVQELVLDNCKANDGKIEGLTDEFVNLEFLSLINVGLFSVSDLPKLPKLKKLELSENRIFGGLDRLAEELPSLTHLNLSGNNLKDISTLEPLKRLDCLKSLDLFGCEVTNRSDYRETVFRLLPQLSYLDGYDREDQEAPDSDVEVDSVEEAPDSDGEVDGVDKEEE--DEEGEDEEEEEDEDGEEEEDEDEEDEDEDEDVEGEDDEDEVSGEEEEFGHDGEVDEDEEDEDEDEDEEEEESGKGEKRKRETDDEGEDD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EST5-1", "uniprot_id": "AN32B_MOUSE", "id": "Q9EST5-1", "name": "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "aln": "MDMKRRIHLELRNRTPAAVRELVLDNCKAMDGKIEGLTDEFVNLEFLSLISVGLFSVSDLPKLPKLKKLELSENRIFGGLDRLAEELPSLTHLNLSGNNLKDISTLEPLKRLDCLKSLDLFGCEVTNRSDYRETVFRLLPQLSYLDGYDREDQEAPDSDVEVDSVEEAPDSDGEVDGVDKEEE--DEEGEDEEEEEDEDGEEEEDEDEEDEDEDEDVEGEDDEDEVSGEEEEFGHDGEVDEDEEDEDEDEDEEEEESGKGEKRKRETDDEGEDD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92688-1", "uniprot_id": "AN32B_HUMAN", "id": "Q92688-1", "name": "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "aln": "MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNLPKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDLFNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPD-------------SDAEVDGVDEEEE--DEEGEDEEDEDDEDGEEEE-FDEED-DEDEDVEGDEDDDEVSEEEEEFGLD------EEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V895-1", "uniprot_id": "AN32A_DROME", "id": "Q9V895-1", "name": "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "aln": "--MEKRIELERRARKVNQITELNLDNCRSTS--IVGLTDEYTALESLSLINVGLTTLKGFPKLPNLKKLELSDNRISSGLNYLTTS-PKLQYLNLSGNKIKDLETLKPLEEFKNLVVLDLFNNDATQVDNYREKIFKMLPSLNFLDGFDCNDEEVQSDG----------DDDDEVNGNDSDEVGVSDEDDDSDDSDEEANGEVSLSEVYNDDLEEDNSDWEGEDEAGEEDEEEDSD--IDDADGDANESAASVNAKDKDGEKEADESQVRGKKRKHDG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *::**.** * *. : ** ****:: . * *** *:. ** ****.*** ::..:****:*******:*** .**: *: . *.* :******::**:.**:**:.:. * ****. :.*: .:***.:*::**.*.:***:* :*:*. . .* **:* *.:* .:*.:*.::.::* . * . : : * :** .. :.:**.. *:** . * : * :*. . : :. .***. *:: .*:. ", "identical_positions": 103, "similar_positions": 93, "identity": "37.05%" }, { "cls_id": "homologset.agr.RGD:621286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WVJ9-1", "uniprot_id": "TWST2_HUMAN", "id": "Q8WVJ9-1", "name": "Twist-related protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEGSSSPVSP-VDSLGTS--------EEEL---------------ERQPKRFGRKR-------------------------------RYSKKS----------------------------SEDGSP---------------TPGKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSD------EMDNKMTSCSY-----------------------------VAHERLSYAFSVWRMEGAWSMSASH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97831-1", "uniprot_id": "TWST2_RAT", "id": "P97831-1", "name": "Twist-related protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEGSSSPVSP-VDSLGTS--------EEEL---------------ERQPKRFGRKR-------------------------------RYSKKS----------------------------SEDGSP---------------TPGKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSD------EMDNKMTSCSY-----------------------------VAHERLSYAFSVWRMEGAWSMSASH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D030-1", "uniprot_id": "TWST2_MOUSE", "id": "Q9D030-1", "name": "Twist-related protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEGSSSPVSP-VDSLGTS--------EEEL---------------ERQPKRFGRKR-------------------------------RYSKKS----------------------------SEDGSP---------------TPGKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSD------EMDNKMTSCSY-----------------------------VAHERLSYAYSVWRMEGAWSMSASH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10627-1", "uniprot_id": "TWIST_DROME", "id": "P10627-1", "name": "Protein twist", "aln": "MMSARSVSPKVLLDISYKPTLPNIMELQNNVIKLIQVEQQAYMQSGYQLQHQQQHLHSHQHHQQHHQQQHAQYAPLPSEYAAYGITELEDTDYNIPSNEVLSTSSNQSAQSTSLELNNNNTSSNTNSSGNNPSGFDGQASSGSSWNEHGKRARSSGDYDCQTGGSLVMQPEHKKLIHQQQQQQQQHQQQIYVDYLPTTVDEVASAQSCPGVQSTCTSPQSHFDFPDEELPEHKAQVFLPLYNNQQQQSQQLQQQQPHQQSHAQMHFQNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDKLSKIQTLKLATRYIDFLCRMLSSSDISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPPEKLSYLFGVWRMEGDAQHQKA-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* :*: .* *:* ** :*** ::*.::: ::: **... ::***. .* :* *: ...::. :*:..**::*************:** :*::*******************:****** ::*.*. :: : :..:* :. *:*** :.****** . . : ", "identical_positions": 76, "similar_positions": 61, "identity": "15.48%" }, { "cls_id": "homologset.agr.RGD:621287", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08009-1", "uniprot_id": "GSTM7_RAT", "id": "P08009-1", "name": "Glutathione S-transferase Mu 7", "aln": "MPMTLGYWDIRGLAHAIRLLLEYTDSSYEEKRYTMGDAPDFDRSQWLNEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNPDFEKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEATCLDAFPNLKDFIARFEGLKKISDYMKSSRFLPRPLFTKMAIWGSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80W21-1", "uniprot_id": "GSTM7_MOUSE", "id": "Q80W21-1", "name": "Glutathione S-transferase Mu 7", "aln": "MPMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNADFEKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEAKCLDAFPNLKDFIARFEGLKKISDYMKTSRFLPRPMFTKMATWGSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28161-1", "uniprot_id": "GSTM2_HUMAN", "id": "P28161-1", "name": "Glutathione S-transferase Mu 2", "aln": "MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********:******:***:***********:********:*:***********************:************:.********:*:*:** ******:**.** **:***:.******* **: ** *::***:****:*** **********************..************:*****:*** ***:*******:***** **.:", "identical_positions": 180, "similar_positions": 30, "identity": "82.57%" }, { "cls_id": "homologset.agr.RGD:621288", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C567-1", "uniprot_id": "NCTR1_MOUSE", "id": "Q8C567-1", "name": "Natural cytotoxicity triggering receptor 1", "aln": "MLPTLTALLCLGLCLSQRINTEKETLPKPIIWAKPSIMVTNGNSVNIWCQGAQSASEYQLYFEGSFFALERPKPSRSMNKVRFFISQMTSHTAGIYTCFYQSGELWSKSSNPLKLVVTGLYDTPNLWVYPRPEVTLGENVTFFCQLKTATSKFFLLKERGSNHIQNKYGNIQAEFPMGPVTRAHRGTYRCFGSYNDYAWSFPSEPVTLLITGGVENSSLAPTDPTSSLDYWEFDLSTNESGLQKDSAFWDHTTQNLIRIGLACIILITLVWLLTEDWLSKRKDHEEANRLTNWECRRRWRMQHYFEEEQRNAISMMELKATPGAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Z0H5-1", "uniprot_id": "NCTR1_RAT", "id": "Q9Z0H5-1", "name": "Natural cytotoxicity triggering receptor 1", "aln": "MLPTLTALLCLGLCLSQRINTEKQTLPKPIIWAKPSIMVTKGNSVNIWCQGAQSASEYQLYFEGSFFALERPKSSRSMNKVKFFISQMTSHTAGIYTCFYQSGELWSESSNPLKLVVTGLYDTPTLWVHPGPEVTLGENVTFSCHLKTATSKFFLLKERESNHIQHKYGNIQAEFPMGPVTRAHRGTYRCFGSYNDYAWSFPSEPVTLLITGEVENTSLAPTDPVSSLDYWEFDLSTKESGLQKDSAFWDHTAQNLIRIGLACIIVMALVWLLAEDWLSRRKDHEKLNRLTSWECRGRRRMHRYHEEEQRDAISMRELKATPGDM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76036-1", "uniprot_id": "NCTR1_HUMAN", "id": "O76036-1", "name": "Natural cytotoxicity triggering receptor 1", "aln": "MSSTLPALLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQLHFEGSLFAVDRPKPPERINKVQFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEMYDTPTLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEGRSSHVQRGYGKVQAEFPLGPVTTAHRGTYRCFGSYNNHAWSFPSEPVKLLVTGDIENTSLAPEDPTFPADTWGTYLLTTETGLQKDHALWDHTAQNLLRMGLAFLVLVALVWFLVEDWLSRKRTRERASRASTWEGRRRLNTQTL---------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .**.****:********.::::*****:***:* :**.: :.*.* *** .* ****:****:**::***... :***:*:*.:*.*: ** *:*:*: *****:.** *.**** :****.* *:* *** **:*** *:*.**** *:**** *.*:*. **::*****:**** *************::*********.**:** :**:**** **. . * * * *.*:***** *:****:***:*:*** :::::***:*.*****::: :*. .* :.** * * . : ", "identical_positions": 180, "similar_positions": 81, "identity": "55.38%" }, { "cls_id": "homologset.agr.RGD:621290", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZA6-1", "uniprot_id": "CD151_RAT", "id": "Q9QZA6-1", "name": "CD151 antigen", "aln": "MGEFNEKKATCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASSTYLATAYILVVAGVVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYVYYQ-------QLNTELKENLKDTMIKRYHQSGHEGVTNAVDKLQQEFHCCGSNNSRDWRDSEWIRSGEADSRVVPDSCCKTVVTGCGKREHASNIYKVEGGCITKLESFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35566-1", "uniprot_id": "CD151_MOUSE", "id": "O35566-1", "name": "CD151 antigen", "aln": "MGEFNEKKATCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASSTYLATAYILVVAGVVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYVYYQ-------QLNTELKENLKDTMVKRYHQSGHEGVSSAVDKLQQEFHCCGSNNSQDWQDSEWIRSGEADSRVVPDSCCKTMVAGCGKRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48509-1", "uniprot_id": "CD151_HUMAN", "id": "P48509-1", "name": "CD151 antigen", "aln": "MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQ-------QLNTELKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLG9-1", "uniprot_id": "A0A8M2BLG9_DANRE", "id": "A0A8M2BLG9-1", "name": "Tetraspanin", "aln": "MADAEEKTNSCGTVCLKYLLFVFNLLFWLAGGAVMAVGIWTLLDKSDYISLLSSNTYMVAAFILIGAGAVVVFTGILGCCATIREQRSLLIVFLILLLLIFLLEITAGVLAYVYYQECFPLCYQLNAELRADLKERMVENYQQPGQEHITRAIDNLQQDLKCCGSNSSADWRDGAWIRN-YADRRLVPDSCCKTPSVGCGVRDHPSNIYKVEGGCISKLEEFILQHLLILGSVGLGIAFVQIVGMIFTCCLYRSLKEEIY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: :**. :***********.:* ***** ********** ********:*.**:.:*:**: **.**:.**:******::*:*.** :::****:****** **:***.*** ***:**: :**: * :.*:*.*:* :: *:*:***:::*****.* **:*. ***. *. *:******** . ** *:*.***********:*** ** :** ::*:**:*** **:.************* * *", "identical_positions": 162, "similar_positions": 61, "identity": "62.31%" }, { "cls_id": "homologset.agr.RGD:621291", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q923V8-1", "uniprot_id": "SEP15_RAT", "id": "Q923V8-1", "name": "Selenoprotein F", "aln": "---MAAGQGGWLRPALGLRLLLATAFQAVSALGAEFSSEACRELGFS-SNLLCSSCDLLGQFNLLPLDPVCRGCCQEEAQFETKKLYAGAILEVCGUKLGRFPQVQAFVRSDKPKLFRGLQIKYVRGSDPVLKLLDDNGNIAEELSILKWNTDSVEEFLSEKLERI---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERR7-1", "uniprot_id": "SEP15_MOUSE", "id": "Q9ERR7-1", "name": "Selenoprotein F", "aln": "---MAAGQGGWLRPALGLRLLLATAFQAVSALGAEFASEACRELGFS-SNLLCSSCDLLGQFNLLPLDPVCRGCCQEEAQFETKKLYAGAILEVCGUKLGRFPQVQAFVRSDKPKLFRGLQIKYVRGSDPVLKLLDDNGNIAEELSILKWNTDSVEEFLSEKLERI---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60613-1", "uniprot_id": "SEP15_HUMAN", "id": "O60613-1", "name": "Selenoprotein F", "aln": "MVAMAAGPSGCLVPAFGLRLLLATVLQAVSAFGAEFSSEACRELGFS-SNLLCSSCDLLGQFNLLQLDPDCRGCCQEEAQFETKKLYAGAILEVCGUKLGRFPQVQAFVRSDKPKLFRGLQIKYVRGSDPVLKLLDDNGNIAEELSILKWNTDSVEEFLSEKLERI---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q802F3-1", "uniprot_id": "SEP15_DANRE", "id": "Q802F3-1", "name": "Selenoprotein F", "aln": "---MAG--------EVYLLWLLP-LLQGLASYGAELSSEACRELGFS-SNLLCSSCELLGQFSLNQLDLPCRQCCQEEAQLENRKLYPGAILEVCGUKLGRFPQVQAFVRSDKPKLFRGLQIKYVRGSDPVLKLLDDNGNIAEELSILKWNTDSVEEFLSEKLERI---------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVJ7-1", "uniprot_id": "Q9VVJ7_DROME", "id": "Q9VVJ7-1", "name": "Selenoprotein F", "aln": "------------MHKCAIFLLLALSCQQIQ---AELTAADCRALGFIKAQLMCSSCEKLDDFGLDTIKPQCKQCCTLDQQPAAQRTYAKAILEVCTCKFRAYPQIQAFIQSGRPAKFPNLQIKYVRGLDPVVKLLDASGKVQETLSITKWNTDTVEEFFETHLAKDGAGKNSYSVVEDADGDDDEDYLRTNRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **. * : **::: ** *** ::*:****: *.:*.* :. *: ** : * :: *. ****** *: :**:***::*.:* * .******** ***:**** .*:: * *** *****:****:. :* : ", "identical_positions": 68, "similar_positions": 37, "identity": "35.23%" }, { "cls_id": "homologset.agr.RGD:621292", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JF5-1", "uniprot_id": "MVD1_MOUSE", "id": "Q99JF5-1", "name": "Diphosphomevalonate decarboxylase", "aln": "MAS-EKPQDLMVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTTTTVAISKDFTEDRIWLNGREEDVGQP-RLQACLREIRRLARKRRSTEDGDTLPLSLSYKVHVASVNNFPTAAGLASSAAGYACLAYTLAQVYGVEG---DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQIAPEWHWPQLRILILVVSADKKQTGSTVGMQTSVETSTLLKFRAESVVPERMKEMTRCIQEQDFQGFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHRFNTHQGQTKVAYTFDAGPNAVIFTLEDTVAEFVAAVRHSFP-PAANGDKFLKGLQVAPVLLSDEL---KAALAVEPSPGGVQYIIATQVGPGPQVLDDTHDHLLGQDGLPQRDL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62967-1", "uniprot_id": "MVD1_RAT", "id": "Q62967-1", "name": "Diphosphomevalonate decarboxylase", "aln": "MAS-EKPQDLMVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTTTTAAISKDFTEDRIWLNGREEDVGQP-RLQACLREIRRLARKRRSTGDGDALPLSLGYKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVEG---DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQIAPEWHWPQLRVLILVVSAEKKPTGSTVGMQTSVATSTLLKFRAESIVPERMKEMTRCIQEQDFQAFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHRFNAHHGQTKVAYTFDAGPNAVIFTLEDTVAEFVAAVRHSFP-PAANGDKFLKGLQVAPVLLSDEL---KTSLATEPSPGGVQYIIATQVGPGPQVLDDPHHHLLGPDGLPQRDL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53602-1", "uniprot_id": "MVD1_HUMAN", "id": "P53602-1", "name": "Diphosphomevalonate decarboxylase", "aln": "MAS-EKP-LAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDFTEDRIWLNGREEDVGQP-RLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVES---DLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAVWHGFP-PGSNGDTFLKGLQVRPAPLSAEL---QAALAMEPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U403-1", "uniprot_id": "MVD1_DANRE", "id": "Q5U403-1", "name": "Diphosphomevalonate decarboxylase", "aln": "MSENILQDLEMVTCTAPVNIAVIKYWGKRDEDLILPVNASLSVTLHQDHLRTTTTIACSRSFHKDCIWLNGKEQDISHP-RLQSCLLEIRRLAQRRKNTGDP---ASDVSNKVHICSVNNFPTAAGLASSAAGYACLVYTLSQLFNVEG---ELSGVARQGSGSACRSLYGGFVQWKLGEQSDGKDSIAEQVASELYWPELRVLILVVSAEQKSVGSTSGMHTSVETSHLLKYRADAVVPGRMEEMIRAIRLRDFPKFGELTMKDSNQFHAICLDTYPPIFYLNNISHQIISLVHRYNQYYGETRVAYTFDAGPNAVIYSLQDYLPEFVEVVRHFFP-PEVNEEEFFKGLPVCPADLSEEM---IRDINMKPTPNGIRYMISTKAGPGPRVVEDPNLHLLGADGLPKKSAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXQ3-1", "uniprot_id": "Q9VXQ3_DROME", "id": "Q9VXQ3-1", "name": "Diphosphomevalonate decarboxylase", "aln": "MFS--------VTCVAPVNIALIKYWGKRHEELILPVNDSISMTLSTDELCAKTTVTASESFETNRMWLNGEEVPFEESSRLQRCLNEVHRLAVASGSQKVP------PTWKLHIASVNNFPTAAGLASSAAGYACLVYSLSRLYDIPLNE-ELTTVARQGSGSACRSLYGGFVQWHRGALDDGSDSVARQIAPSDHWPNMHVLILVVNDARKKTASTRGMQQAVKTSQLIKHRVDQVVPDRIIRLREAIASHDFQAFAEITMKDSNQFHAIALDTYPPCVYMNDVSHSIVSFVHDYNERMGSYHAAYTFDAGPNACLYVLAEHVPHLLSAIQKVFPNDLADGGTYLRGLPIPKVQDAESS---KLDSLDVHAKNAFRYIIHTKVGEGPKELSADNSLLIN--GLPLK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32377-1", "uniprot_id": "MVD1_YEAST", "id": "P32377-1", "name": "Diphosphomevalonate decarboxylase", "aln": "MTV------YTASVTAPVNIATLKYWGKRDTKLNLPTNSSISVTLSQDDLRTLTSAATAPEFERDTLWLNGEPHSIDNE-RTQNCLRDLRQLRKEMESKDAS--LPTLSQWKLHIVSENNFPTAAGLASSAAGFAALVSAIAKLYQLPQSTSEISRIARKGSGSACRSLFGGYVAWEMGKAEDGHDSMAVQIADSSDWPQMKACVLVVSDIKKDVSSTQGMQLTVATSELFKERIEHVVPKRFEVMRKAIVEKDFATFAKETMMDSNSFHATCLDSFPPIFYMNDTSKRIISWCHTINQFYGETIVAYTFDAGPNAVLYYLAENESKLFAFIYKLFG-SVPGWDKKFTTEQLEAFNHQFESSNFTARELDLELQKDVARVILTQVGSGPQ--ETNESLIDAKTGLPKE---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: .****** :******. * ** * *:*:** *.* : *: . : .* : :****. . . * * ** ::: * . *:*: * ***************:*.*. :::::: : ::: :**:*********:**:* *. * ** **:* *:* . **::: :***. :* ..** **: :* ** *:: * : :** *: : ..* :** *.: ** ***.*** .**::** *:* * *: * * *. .********** :: * : ..:. : : * . : : . . :* *:.* **: . : *** ", "identical_positions": 138, "similar_positions": 94, "identity": "33.58%" }, { "cls_id": "homologset.agr.RGD:621293", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64578-1", "uniprot_id": "AT2A1_RAT", "id": "Q64578-1", "name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 1", "aln": "MEAAHSKSTEECLSYFGVSETTGLTPDQVKRHLEKYGPNELPAEEGKSLWELVVEQFEDLLVRILLLAACISFVLAWFEEGEETVTAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAVGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICSLNEFSITGSTYAPEGEVLKNDKPVRAGQYDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGPVKEKIMSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSAKFMEYEMDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFSENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFLYAEDGPHVSYHQLTHFMQCTEHNPEFDGLDCEVFEAPEPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDFTQWLMVLKISLPVIGLDELLKFIARNYLEG--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R429-1", "uniprot_id": "AT2A1_MOUSE", "id": "Q8R429-1", "name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 1", "aln": "MEAAHSKSTEECLSYFGVSETTGLTPDQVKRHLEKYGPNELPAEEGKSLWELVVEQFEDLLVRILLLAACISFVLAWFEEGEETVTAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAVGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDVCSLNEFSITGSTYAPEGEVLKNDKPVRAGQYDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGPVKEKIMSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSAKFMEYEMDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFSENEEVTDRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFLYAEDGPHVSYHQLTHFMQCTEHNPEFDGLDCEVFEAPEPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDFTQWLMVLKISLPVIGLDELLKFIARNYLEG--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14983-1", "uniprot_id": "AT2A1_HUMAN", "id": "O14983-1", "name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 1", "aln": "MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISLPVIGLDEILKFVARNYLEDPEDERRK-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22700-1", "uniprot_id": "ATC1_DROME", "id": "P22700-1", "name": "Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type", "aln": "MEDGHSKTVEQSLNFFGTDPERGLTLDQIKANQKKYGPNELPTEEGKSIWQLVLEQFDDLLVKILLLAAIISFVLALFEEHEETFTAFVEPLVILLILIANAVVGVWQERNAESAIEALKEYEPEMGKVVRQDKSGIQKVRAKEIVPGDLVEVSVGDKIPADIRITHIYSTTLRIDQSILTGESVSVIKHTDAIPDPRAVNQDKKNILFSGTNVAAGKARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQQKLDEFGEQLSKVISVICVAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIFDKVEGNDSSFLEFEMTGSTYEPIGEVFLNGQRIKAADYDTLQELSTICIMCNDSAIDYNEFKQAFEKVGEATETALIVLAEKLNSFSVNKSGLDRRSAAIACRGEIETKWKKEFTLEFSRDRKSMSSYCTPLKASRLGTGPKLFVKGAPEGVLERCTHARVGTTKVPLTSALKAKILALTGQYGTGRDTLRCLALAVADSPMKPDEMDLGDSTKFYQYEVNLTFVGVVGMLDPPRKEVFDSIVRCRAAGIRVIVITGDNKATAEAICRRIGVFAEDEDTTGKSYSGREFDDLSPTEQKAAVARSRLFSRVEPQHKSKIVEFLQSMNEISAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLADDNFSSIVSAVEEGRAIYNNMKQFIRYLISSNIGEVVSIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPRKADEGLISGWLFFRYMAIGFYVGAATVGAAAWWFVFSDEGPKLSYWQLTHHLSCLGGGDEFKGVDCKIFSDPHAMTMALSVLVTIEMLNAMNSLSENQSLITMPPWCNLWLIGSMALSFTLHFVILYVDVLSTVFQVTPLSAEEWITVMKFSIPVVLLDETLKFVARKIADGESPIYKMHGIVLMWAVFFGLLYAMML", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .*:*:.*:.* :**.. *** **:* : :*** ****:****::*:**:***:****:****** ****** *** ***.******:**********:**********.*************** * *:..:*:::*::*****:***:****:****** * *****:****************:.:************:******:***** *:* **:.* ***** :*: **: ********************:****** *********.*****::*************************************************************************.:***:***:*: . : **.:***** * ***: *.: ::..:** * **:*** :****::*:** * .:*********** .*.**:* *..: .*.: . * **.. *. **************** **:* *:** ..* *:*********::**.:.*****:****..:* **::: ::*************. *:* * :** *.**::* :** :***************** .** ** ******:******.** *******:*.*:*:.:.::*:*******. :**: * *: *:****.*******:*** :**:******************************:*:**********:**:***********************:****.*******************************************::***...* ************** **************:::::**::.* ****.:.* . .*.*:**::*. *..************* **:*********: **** *:**:**:.**::***:***** *. :*:: .*. :*: *:*:*:**: *** ***:**: :. ", "identical_positions": 707, "similar_positions": 193, "identity": "69.31%" }, { "cls_id": "homologset.agr.RGD:621294", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28037-1", "uniprot_id": "AL1L1_RAT", "id": "P28037-1", "name": "Cytosolic 10-formyltetrahydrofolate dehydrogenase", "aln": "----MKIAVIGQSLFGQEVYCQLR-KEGHEVVGVFTIPDKDGKADPLGLEAEKDGVPVFKFPRWRARGQALPEVVAKYQALGAELNVLPFCSQFIPMEVINAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGTAPRCPQSEEGATYEG-IQKKETAKINWDQPAEAIHNWIRGNDKVPGAWT-----EACGQKLTFFNSTLNTSGLSTQGEALPIPGAHRPGVVTKAGLILFGNDDRMLLVKNIQLEDGKMMPASQFFKGSAS-SDLELTEAELATAEAVRSSWMRILPNVPEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMATTFRGFIQLLVRKLRGEDD---ESECVINYVEKAVNKLTLQMPYQLFIGGEFVDAEGSKTYNTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENGLWGKINARDRGRLLYRLADVMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEESIHNQFVQKVVEEVEKMKIGNPLERDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCGGNQVP-RPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRIKTVTFEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0Y6-1", "uniprot_id": "AL1L1_MOUSE", "id": "Q8R0Y6-1", "name": "Cytosolic 10-formyltetrahydrofolate dehydrogenase", "aln": "----MKIAVIGQSLFGQEVYCQLR-KEGHEVVGVFTIPDKDGKADPLGLEAEKDGVPVFKFPRWRARGQALPEVVAKYQALGAELNVLPFCSQFIPMEVINAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTIFWADDGLDTGDLLLQKECDVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGTAPRRPQPEEGATYEG-IQKKETAMINWDQPAEAIHNWIRGNDKVPGAWT-----EACGQKLTFFNSTLNTSGLVAQGEALPIPGAHRPGLVTKAGLILFGNDDRMLLVKNIQLEDGKMMPASQFFKGSAS-SALELTEEELATAEAVRSSWMRILPNVPEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMATTFGDFIQLLVRKLRGEDG---ESECVINYVEKAVKKLTLQMPYQLFIGGEFVDAEGAKTYSTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENGLWGKINARDRGRLLYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDQFVQKVVEEVGKMKIGNPLDRDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCGGNQVP-RPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRIKTVTFEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75891-1", "uniprot_id": "AL1L1_HUMAN", "id": "O75891-1", "name": "Cytosolic 10-formyltetrahydrofolate dehydrogenase", "aln": "----MKIAVIGQSLFGQEVYCHLR-KEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEG-IQKKETAKINWDQPAEAIHNWIRGNDKVPGAWT-----EACEQKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMLLVKNIQLEDGKMILASNFFKGAAS-SVLELTEAELVTAEAVRSVWQRILPKVLEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMASTFGDFIQLLVRKLRGDDE---EGECSIDYVEMAVNKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGRWGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVP-RPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVTFEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VIC9-1", "uniprot_id": "Q9VIC9_DROME", "id": "Q9VIC9-1", "name": "10-formyltetrahydrofolate dehydrogenase", "aln": "MALKMRIAIIGQSNFAADVLELLLDRSNIQIVGVFTIPDKGSREDILATTATIHNIPVFKFACWRRKGVALPEVLEQYKSVGATLNVLPFCSQFIPMEVINGALLGSICYHPSILPRHRGASAISWTLIEGDEVAGFSIFWADDGLDTGPLLLTRQTNVESTDTLDTIYKRFLYPEGVKAMGVAVDMVASGTAPKIIQPEVGATYDPAMFKTENQVINLQATAEKIWNFVRGLDSVPGAIATVLHGNGTEEQIRLFGAHLYSAGPVSNGKVLRLRGLTKTAWIHSGGLLIEGTDGAFVNIRRIKR-GTKVISASEWFKQAEDQSITDFSEDELVKRSLLAGIWKAILK--EDVESSTDFFASGAGSMDVVRLVEEVKEAFD-VPLQNEQVFMAPVFEEFFSLLVRFLRQGSAGFGNQQLDFEAFTLKANKREIRVPTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFY-GSWRQITPRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQGNTIPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTMTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGTVFVNVYNKTDVAAPFGGFKQSGYGKDLGQEALNEYLKTKCVTVEY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**:**** *. :* * :.. ::*****:***..: * *. * ..:****:. ** :* ***:*: :*:::** **************:*... *** ****:**********.****.**: .**:*********** *** :: :* . **:.*:*:***:***:*.* ** ::*.*.**: *.* ****: : *.*. ** : .** * *::** *.**** : :. ::: :*.: * ::* .:*..* : * :.. : ..**:: *.*. :: ::.*: . *:: **::** : . * :::* **.. . : . * ** :**.***** ***.*:*********** * : *:**:*:**..* *:.**** ** . : : :: . .:* :::* ****.*******. :* . :***: .*:*:*: *..:****** **:.** * * :*..*:**:*: .***:**:::*******::*:****************:::************ ***:* ****. **:*:***:****:: ************ ***:***** :*****. ***********::**:* **:*:***.** .** ::** ***:****** :********* **:** *****************::***: **********************: **::*:::*:::: .*.:*:**:*.* ******.**: **:*:*::**.***.** ** :** *:** *****:* *.*:**:******:****:* ..*:*:::.*** **:********:**.*** .:*:::*****:*.*****************:*****: ******: * **.**", "identical_positions": 518, "similar_positions": 242, "identity": "56.43%" }, { "cls_id": "homologset.agr.RGD:621295", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17256-1", "uniprot_id": "KIME_RAT", "id": "P17256-1", "name": "Mevalonate kinase", "aln": "MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALN-LRTFLVLRPQSN-GKVSLNLPNVGIKQVWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNE-----GLSLLAFLYLYLAICRKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQ----GKMSS-----LKRLPALQILLTNTKVPRSTKALVAGVRSRLIK-FPEIMAPLLTSIDAISLECERVLGEMAAAP---------VPEQYLVLEELMDMNQHHLNALGVGHASLDQLCQVTAAHGLHS-KLTGAGGGGCGITLLKPGLERAKVEAAKQALTG-CGFDCWETSIGAPGVSMHSATSIEDPVRQALG-L----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R008-1", "uniprot_id": "KIME_MOUSE", "id": "Q9R008-1", "name": "Mevalonate kinase", "aln": "MLSEALLVSAPGKVILHGEHAVVHGKVALAAALN-LRTFLLLRPQSN-GKVSVNLPNIGIKQVWDVGMLQRLDTSFLEQGDVSVPTLEQLEKLKKMGDLPRDRAGNE-----GMALLAFLYLYLAICRKQRTLPSLDMVVWSELPPGAGLGSSAAYSVCLAAALLTACEEVSNPLKDGVSVSRWPEEDLKSINKWAFEGERVIHGNPSGVDNAVSTWGGALRFQQ----GTMSS-----LKSLPSLQILLTNTKVPRSTKALVAAVRSRLTK-FPEIVAPLLTSIDAISLECERVLGEMVAAP---------VPEQYLVLEELIDMNQHHLNALGVGHNSLDQLCQVTAAHGLHS-KLTGAGGGGCGITLLKPGLEQATVEAAKQALTS-CGFDCWETSIGAPGVSTHSAAAVGDPVRQALG-L----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03426-1", "uniprot_id": "KIME_HUMAN", "id": "Q03426-1", "name": "Mevalonate kinase", "aln": "MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLN-LRTFLRLQPHSN-GKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTE-----RLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQ----GKISS-----LKRSPALQILLTNTKVPRNTRALVAGVRNRLLK-FPEIVAPLLTSIDAISLECERVLGEMGEAP---------APEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHS-KLTGAGGGGCGITLLKPGLEQPEVEATKQALTS-CGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P07277-1", "uniprot_id": "ERG12_YEAST", "id": "P07277-1", "name": "Mevalonate kinase", "aln": "-MSLPFLTSAPGKVIIFGEHSAVYNKPAVAASVSALRTYLLISESSAPDTIELDFPDISFNHKWSINDFNAITEDQVNSQKLAKAQQATDGLSQELVSLLDPLLAQLSESFHYHAAFCFLYMFVCLCP---HAKNIKFSLKSTLPIGAGLGSSASISVSLALAMAYLGGLIG-----SNDLEKLSENDKHIVNQWAFIGEKCIHGTPSGIDNAVATYGNALLFEKDSHNGTINTNNFKFLDDFPAIPMILTYTRIPRSTKDLVARVRVLVTEKFPEVMKPILDAMGECALQGLEIMTKLSKCKGTDDEAVETNNELYEQLLELIRINHGLLVSIGVSHPGLELIKNLSDDLRIGSTKLTGAGGGGCSLTLLRRDITQEQIDSFKKKLQDDFSYETFETDLGGTGCCLLSAKNLNKDLKIKSLVFQLFENKTTTKQQIDDLLLPGNTNLPWTS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :*.*******:.***:.*:.* *:*.::. ***:* : * ..:.:.:*::.::: *.: :: : . ::. .:. . ::: .* : :.***:::.:* .:.: : * ** ********: **.:* *: : : .::* . :*:**: **: ***.***:**:*:*:*.** :.: *.:.: *. *:: ::** *::**.*: *** ** : : ***:: *:* ::. :*: .:: :: . * * * **: :*: * ::**.* .*: : ::: : * **********.:***: .: : ::: *: * . .:: **.:*..* . ** : . :: : ", "identical_positions": 115, "similar_positions": 148, "identity": "25.44%" }, { "cls_id": "homologset.agr.RGD:621296", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQV6-1", "uniprot_id": "TPP1_RAT", "id": "Q9EQV6-1", "name": "Tripeptidyl-peptidase 1", "aln": "MGLQARFLGLLALVIAGKCTHSPEPDQRWMLPPGWVSLGRVDPEEELSLTFALKQQNLDRLSELVQAVSDPSSPRYGKYLTLEDVAELVQPSPLTLRTVQKWLLAAGARDCHSVTTQDFLTCWLSVRQAELLLPGAEFHRYVGGPAKTHIIRSPHPYQLPQALAPHVDLVAGLHRFPPLSSPRQR-PEPQGVGPVGLHLGVTPSVLRQRYNLTARDVGSGTTNNSQACAQFLEQYFHNSDLTEFMRLFGSSFAHQASVARVVGKQGRGRAGIEASLDVEYLMSAGANISTWVYSSPGRHEAQEPFLQWLLLLSNESSLPHVHTVSYGDDEDSLSSVYIQRVNTEFMKAAARGLTLLFASGDTGAGCWSVSG-RHKFRPSFPASSPYVTTVGGTSFKNPFLVTNEVVDYISGGGFSNVFPQPSYQEEAVAQFLKSSSHLPPSSYFNASGRAYPDVAALSDGYWVVSNMVPIPWVSGTSASTPVFGGILSLINEHRLLNGRPPLGFLNPRLYQQHGAGLFDVTHGCHESCLNEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O89023-1", "uniprot_id": "TPP1_MOUSE", "id": "O89023-1", "name": "Tripeptidyl-peptidase 1", "aln": "MGLQARLLGLLALVIAGKCTYNPEPDQRWMLPPGWVSLGRVDPEEELSLTFALKQRNLERLSELVQAVSDPSSPQYGKYLTLEDVAELVQPSPLTLLTVQKWLSAAGARNCDSVTTQDFLTCWLSVRQAELLLPGAEFHRYVGGPTKTHVIRSPHPYQLPQALAPHVDFVGGLHRFPP-SSPRQR-PEPQQVGTVSLHLGVTPSVLRQRYNLTAKDVGSGTTNNSQACAQFLEQYFHNSDLTEFMRLFGGSFTHQASVAKVVGKQGRGRAGIEASLDVEYLMSAGANISTWVYSSPGRHEAQEPFLQWLLLLSNESSLPHVHTVSYGDDEDSLSSIYIQRVNTEFMKAAARGLTLLFASGDTGAGCWSVSG-RHKFRPSFPASSPYVTTVGGTSFKNPFLITDEVVDYISGGGFSNVFPRPPYQEEAVAQFLKSSSHLPPSSYFNASGRAYPDVAALSDGYWVVSNMVPIPWVSGTSASTPVFGGILSLINEHRILNGRPPLGFLNPRLYQQHGTGLFDVTHGCHESCLNEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14773-1", "uniprot_id": "TPP1_HUMAN", "id": "O14773-1", "name": "Tripeptidyl-peptidase 1", "aln": "MGLQACLLGLFALILSGKCSYSPEPDQRRTLPPGWVSLGRADPEEELSLTFALRQQNVERLSELVQAVSDPSSPQYGKYLTLENVADLVRPSPLTLHTVQKWLLAAGAQKCHSVITQDFLTCWLSIRQAELLLPGAEFHHYVGGPTETHVVRSPHPYQLPQALAPHVDFVGGLHRFPPTSSLRQR-PEPQVTGTVGLHLGVTPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSG-RHQFRPTFPASSPYVTTVGGTSFQEPFLITNEIVDYISGGGFSNVFPRPSYQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPVFGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W2M8-1", "uniprot_id": "TPP1_DANRE", "id": "F8W2M8-1", "name": "Tripeptidyl-peptidase 1", "aln": "MRVAVFVLSFIWLVNG----ELLEADQDAVVPGDWTFLGRVGPLEEVELTFALKQQNVSKMEELLKLVSDPDSHQYGKYLSLDEVAALSRPSPLTEKVVENWLRSHGVMDCHTIITRDFLQCVMTVEVAEALLPGSKFHRFS--KNTKTLLRSTSQYSVHEDVHQHLDFVGGVHRFPQKRKIVSKGWEGARQAILGYHLGVTPAVIRNRYNLTAKDVGT-AANNSQAVAQFLEQYYHPADLAEFMSLFGGGFTHMSTVERVVGTQGGGKAGIEASLDVEYIMSSGANISTWVFTNPGRHESQEPFLQWMLLLSNMSAVPWVHTISYGDDEDSLSEAYMNRINIEFMKAGLRGISMLFASGDSGAGCRHLTKERNTFRPSFPASSPYVTTVGGTSFQNPFKLSYEVTDYISGGGFSNVFPMPDYQVDAVRAYLKSVQSLPPQTYFNTTGRAYPDLAALSDNYWVVSNRVPIPWVSGTSASTPVVGGILSLINDQRFLKGLPALGFINPRLYKMQGKGLYDVTVGCHLSCLDDKVEGKGFCASPSWDPVTGWGTPNYPVFLASLMD-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . .*.:: *: . *.** :* .*. ***..* **:.*****:*:*:.::.**:: ****.* :*****:*::** * :***** .*::** : *. .*.:: *:*** * :::. ** ****::**:: . ::**. *.: : : *:*:*.*:**** . .: * . :. ******:*:*:*****::***: ::***** *******:* :**::** ***..*:* ::* :*** ** *:*********:*:**:********::.*****.*******::**** *::* ***:**********. *::*:* *:***. **:::******:**** :: *: ***:****************::** :: *:.************* * ** :** :*.* ***.:***::******:*****.****** ***************.********::*:*.* *.***:*****: :* **:*** *** ***:::***:***:.*.***********:*.:* :*:: ", "identical_positions": 321, "similar_positions": 150, "identity": "56.81%" }, { "cls_id": "homologset.agr.RGD:621297", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q03346-1", "uniprot_id": "MPPB_RAT", "id": "Q03346-1", "name": "Mitochondrial-processing peptidase subunit beta", "aln": "MAAAAVSRTLLPVAGRRLWGFTRRLPLRAAAAQPLYFGGDRLRSTQAAPQVVLNVPETQVTCLENGLRVASENS-GISTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLVDYITTHYKGPRIVLAAAGGVCHNELLELAKFHFGDSLCAHKGDVPALPP---CKFTGSEIRVRDDKMPLAHLAVAIEAVGWTHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHG-NLCHSFQSFNTSYTDTGLWGLYMVCEQ--ATVADMLHAVQKEWMRLCT-AVSESEVARAKNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVDAEMVREVCTKYIYGKSPAIAALGPIERLPDFNQICSNMRWTRD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CXT8-1", "uniprot_id": "MPPB_MOUSE", "id": "Q9CXT8-1", "name": "Mitochondrial-processing peptidase subunit beta", "aln": "MAAAALSRTLLPEARRRLWGFTRRLPLRRAAAQPLYFGGDRLRSTQAAPQVVLNVPETQVTCLENGLRVASENS-GLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSRDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSINRKDLVDYITTHYKGPRIVLAAAGGVCHNELLELAKFHFGDSLCSHKGAIPALPP---CKFTGSEIRVRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHG-NLCHSFQSFNTSYTDTGLWGLYMVCEQ--ATVADMLHVVQNEWKRLCT-DVTESEVARAKNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVDAETVRRVCTKYIHDKSPAIAALGPIERLPDFNQICSNMRWIRD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75439-1", "uniprot_id": "MPPB_HUMAN", "id": "O75439-1", "name": "Mitochondrial-processing peptidase subunit beta", "aln": "MAAAAARVVLSSAARRRLWGFSESLLIRGAAGRSLYFGENRLRSTQAATQVVLNVPETRVTCLESGLRVASEDS-GLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGDSLCTHKGEIPALPP---CKFTGSEIRVRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHG-NLCHSFQSFNTSYTDTGLWGLYMVCES--STVADMLHVVQKEWMRLCT-SVTESEVARARNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAETIREVCTKYIYNRSPAIAAVGPIKQLPDFKQIRSNMCWLRD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFF0-1", "uniprot_id": "Q9VFF0_DROME", "id": "Q9VFF0-1", "name": "Mitochondrial-processing peptidase subunit beta", "aln": "MALRVLGVTQN------MRSFMRGVDMIK-----------RYKSAATLQKTLLNIPATQVTKLDNGLRVASEDS-GASTATVGLWIDAGSRSENEKNNGVAHFLEHMAFKGTAKRSQTDLELEVENLGAHLNAYTSREQTVFYAKCLSKDVPKAVEILADIIQNSKLGEAEIARERSVILREMQEVESNLQEVVFDHLHATAYQGTPLGQTILGPTKNIQSIGKADLTDYIQTHYKASRIVLAAAGGVKHDDLVKLACSSLGG--LEASVLPAEVTP---CRFTGSEVRVRDDSLPLAHVAIAVEGCGWTDQDNIPLMVANTLVGAWDRSQGGGANNASNLARASAED-NLCHSFQSFNTCYKDTGLWGIYFVCDP--LQCEDMLFNVQTEWMRLCT-MVTEAEVERAKNLLKTNMLLQLDGTTPICEDIGRQILCYNRRIPLHELEQRIDAVSVGNVRDVAMKYIYDRCPAVAAVGPVENLPDYNRIRSSMYWLRV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P10507-1", "uniprot_id": "MPPB_YEAST", "id": "P10507-1", "name": "Mitochondrial-processing peptidase subunit beta", "aln": "MFSRTASKFRN----------TR-----------------RLLSTISS-----QIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSMVALGNTSTVPNVSYIEEKLNQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . * *: : ::* *:.: * .** :*:* . *:.***:::***** ** ****.******:***** :*** .:***:**:*:*********:**:***.:..*:*:**:**:**: :* *.:: * ***.**:** :**:. :*****:** :*:. .**:***** :**:** : ** *** .:**. *:***.**.* *:.*:. * :* . . * .* ::::.:* :*:*:*:*. .*: * : :.:::::* ***: * * * .* ** :... .*.:*: **.*.* *:****:*:* : :: : .** *: : ::::** **: **: :**.***:*.* ******:: .:*:. *: ::* : : . : .: ::.*:* . :*: . * ..: ", "identical_positions": 177, "similar_positions": 149, "identity": "35.61%" }, { "cls_id": "homologset.agr.RGD:621299", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35370-1", "uniprot_id": "O35370_RAT", "id": "O35370-1", "name": "Thrombomodulin", "aln": "---------------------------------------------------------MLGVFLLGVLAPAGLGISALAKLQPKG---------SQCVGNECFALFQDPVTFLDASQACQRLQGHLMTVRSSVAADVISLLVS-DSSMDSR-PWIGLQLPQGCGDPVHLG-PLRGFQWVTGDNHTSYS---------RWARPNDQSPPLCGPLCVTVSTATEAAPGEPAWEEKPCENETKGFLCEFYFAAFCRPLRVNTRDPEGAH----------ISSTYNTPLGVSGADFQTLPIGSSATVAPFGLELVCRALPGTSEGHWTREVTGAWNCSVEN------GGCEYMCNRSANGPRCVCPSGGDLQADGRSCAKPVAQLCNELCQHFCVNNSDVPGSYSCMCETGYQLAADGHRCEDVDDCKQGPNPCPQLCSN-TEGGFECRCYDGYELVDGECVEQLDPCFRSKCEYQCQPVNSTHYNCICAEGFAPKLDDPDRCEMFCNETSCPADCDPNSPSFCQCPEGFILDEGSICTDIDECSQGECLTNECRNLPGSYECICG----------PDTALAGQISKDCDPIPVLEDS------EDGGSGEHPSSNPTVVSSTVPP--------SARPMHSGVLIGISIASLSLVVALLALLCHLRKKQGTAR--------------AELEYKCTSSAKEVVLQHVRTDRTLQKF-------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15306-1", "uniprot_id": "TRBM_MOUSE", "id": "P15306-1", "name": "Thrombomodulin", "aln": "---------------------------------------------------------MLGIFFLGVLAPASLGLSALAKLQPTG---------SQCVEHECFALFQGPATFLDASQACQRLQGHLMTVRSSVAADVISLLLS-QSSMDLG-PWIGLQLPQGCDDPVHLG-PLRGFQWVTGDNHTSYS---------RWARPNDQTAPLCGPLCVTVSTATEAAPGEPAWEEKPCETETQGFLCEFYFTASCRPLTVNTRDPEAAH----------ISSTYNTPFGVSGADFQTLPVGSSAAVEPLGLELVCRAPPGTSEGHWAWEATGAWNCSVEN------GGCEYLCNRSTNEPRCLCPRDMDLQADGRSCARPVVQSCNELCEHFCVSNAEVPGSYSCMCETGYQLAADGHRCEDVDDCKQGPNPCPQLCVN-TKGGFECFCYDGYELVDGECVELLDPCFGSNCEFQCQPVSPTDYRCICAPGFAPKPDEPHKCEMFCNETSCPADCDPNSPTVCECPEGFILDEGSVCTDIDECSQGECFTSECRNFPGSYECICG----------PDTALAGQISKDCDPIPVREDTK-----EEEGSGEPPVS-PTPGSPTGPP--------SARPVHSGVLIGISIASLSLVVALLALLCHLRKKQGAAR--------------AELEYKCASSAKEVVLQHVRTDRTLQKF-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07204-1", "uniprot_id": "TRBM_HUMAN", "id": "P07204-1", "name": "Thrombomodulin", "aln": "---------------------------------------------------------MLGVLVLGALALAGLGFPAPAEPQPGG---------SQCVEHDCFALYPGPATFLNASQICDGLRGHLMTVRSSVAADVISLLLNGDGGVGRRRLWIGLQLPPGCGDPKRLG-PLRGFQWVTGDNNTSYS---------RWARLDLNGAPLCGPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPG-AAAAA----------VSITYGTPFAARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVEN------GGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVN-TQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICG----------PDSALARHIGTDCDSGKVDGGD--------SGSGEPPPS-PTPGSTLTPP--------AVGLVHSGLLIGISIASLCLVVALLALLCHLRKKQGAAR--------------AKMEYKCAAPSKEVVLQHVRTERTPQRL-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VH23-1", "uniprot_id": "Q9VH23_DROME", "id": "Q9VH23-1", "name": "", "aln": "-----------------------MALSSRVLCLR------------------LQHHLLLVILTIFLLCPAASAQNEEEDGPYRGKYLGKLNSYHHQVSGDVYAVNEYTFLIVGFNYDGNGADTFFWSGASNRPGPQGFIVP--DEYG--KTNILDRYHNKDFTLTLPDRKKITEIKWLAVYDLSSQNNFGDVYIPEEFDPPMSQLGGTFSKRSHNVSSSSVEILDSKTIRIKDFTYDGRGKRTFFWTGVGPQPSSRGSKLPDERGYLDPIRQYNKETIELELPGDKTIFDIDWISVYDVADNENYGHVLFNDKLNVPPSL--VKVTPFEFSLP----------NCRQLHK-DMQVSWEVFGPQITFQLSG-QVGGNDYMSFGISGSDVSSQMIGSDVVVAYIDDIR--GYTVDYNITSLAPCVQVLGQNKGVCRDDVVGGLDSFQLNTYSRKDGINTISFRRTLKSSDDG-DKEIFLDRSNYVIWAFGPLDSNNEPAFHTYYP----KSDIVIDFNTTEPVNDCFAFTKRAETTNPPVWERTRITDATVRTFNAYLGPSGGLRGYQGLTNHVSSGLAWYINGYMIPELYLKRGLTYTFKVRGGNNPHSPEHYHPLVITDDPQGGYDRLSDAKQSEIRVLAGVEFTRRGRPKPTAAGPLCLSRYPQNSDRRLDDNFPTFKKFNRSLITECVEGEPALLEITPNITWPDTVYYNSFTHGNMGWKIHIVDSYTNLKSGSMGLSWSLCIILLPWLVLQN----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4K709-1", "uniprot_id": "A0A0B4K709_DROME", "id": "A0A0B4K709-1", "name": "Protein Skeletor", "aln": "MWRKASRLVRETTSWKTRRQGQAEAPSAAVATIKPSTRTSTPIAHGLPIIITWSQLAIVAAVAVLLQCHVCQAAGRAPPEPYYGRYIGDFTNFAHGIKGQIYAVDESTLFVKSFAYDGTGPDAFFWVGKTPRPSPDGYIIPYPEEYTGMDPPILQAHNRTDIILRLPMGKRIKDIRWLSVWCRRFTVDFGEVFIPPNLDVPKPRVLPEFKRLAHGLRSSNISVLDAKTFYIPNLHYDGAGPDAYFWVGNGSEPNIMGIKVPNESGSLEPLRGYQGEDIEIQLPESLTVYDIDWLAVWCVEYRHNFGHVYIPRDLDVPPALGQTKITPSWWYSPTTTTPRPVYSNCREILPNKLQIKWELQGEYLQVELFG-RITEDQYMAFGLSGANGRAQMSQSDVVVAFYDTTTRVFRAEDYFISDLSQCD----GQRGACPDERIGGRNDVIVLSGDRKNGVTSIRYKRLLQPNEAIYDAPIPTDREVSVIAAIGPLNARKEANAHSHTASDHNQDDIRINFSARNDHACQSSLYDVKDESGPRPWPTRKIEG--VRKFRASIGPTGGKRGYTSITGVPSWGIAWYVNDLLIPEITVERGLTYEFIIEGGNDPSQPARYHPFYITDSPEGGLGQKMGLEARKQKAYAGVEYDEDGNAIPTGGGRYCEWEHQTIDR---SAEIDTFEEYMKTLVFKCEDGEPGYLNWTVPTNAPDQLYYQCFTHNNLGWKINVVDMGSSGGSKVSSHQFSFYGIFTVFSLVATSLPFFGHVLA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : . . . * : : : :*: . . . .: : .. :: : : . : ::*:: . . . : :: . . * * .* . * *:: :.: * . . . .. : . .*. .: * . . : : : .: * * : ** : . :* : .. : : . . . . * : : : . :. :.: . * . .:* :. . *.. * . *:. . . . : :* : . ", "identical_positions": 23, "similar_positions": 104, "identity": "3.01%" }, { "cls_id": "homologset.agr.RGD:621300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63198-1", "uniprot_id": "CNTN1_RAT", "id": "Q63198-1", "name": "Contactin-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKTPLLVSHLLLISLTSCLGEFTWHRRYG--------------HGVSEEDKGFGPIFEEQPINTIYPEES--LEGKVSLNCRARASPFPVYKWR------MNNGDVDLTN---DRYSMVGGNLVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEDRPEVKVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVESSDRGNYSCFVSSPSITKSVFSKFIPLIPIPER-TTKPYPADIVVQFKDIYTMMGQNVTLECFALGNPVPDIRWRKVLEPMP-TTAEISTSGAVLKIFNIQLEDEGLYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHKG-ELRLYDVTFE------------NAGMYQCIAENAYGTIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITNPTRIILAPINADITVG-ENATMQCAASFDPSLDLTFVWSFNGYVIDFNKEITNIHYQRNFMLDA---NGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQT-KTILSDDWKDAKTDPPIIEGN----MESAKAVDLIPWMEYEFRVVATNTLGTGEPSIPSNRIKTDGAAPNVAPSDVGGGGGTNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMT-PSTAFQVKVKAFNNKGDGPYSLIAVINSAQDAPSEAPTEVGVKVLSSSEISVHWKHVLEK------IVESYQIRYWAG-HDKEAAAHRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPSSDVIETFTRKAPPSQPPRIISSVR--SGSRYIITWDHVVALSNESTVTGYKILYRPDGQHDGKLFSTHK------HSIEVPIPRDGEYVVEVRAHSDGGDG---------VVSQVKISG-VSTLSSGLLSLLLPSLGFLVFYSEF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P12960-1", "uniprot_id": "CNTN1_MOUSE", "id": "P12960-1", "name": "Contactin-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMPLLVSHLLLISLTSCLGDFTWHRRYG--------------HGVSEEDKGFGPIFEEQPINTIYPEES--LEGKVSLNCRARASPFPVYKWR------MNNGDVDLTN---DRYSMVGGNLVINNPDKQKDAGVYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVKVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVESSDRGNYSCFVSSPSITKSVFSKFIPLIPIPER-TTKPYPADIVVQFKDIYTMMGQNVTLECFALGNPVPDIRWRKVLEPMP-STAEISTSGAVLKIFNIQLEDEGLYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCIATGKPIPTIRWLKNGYSYHKG-ELRLYDVTFE------------NAGMYQCIAENAYGSIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITNPTRIILAPINADITVG-ENATMQCAASFDPALDLTFVWSFNGYVIDFNKEITHIHYQRNFMLDA---NGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQT-KTILSDDWKDAKTDPPIIEGN----MESAKAVDLIPWMEYEFRVVATNTLGTGEPSIPSNRIKTDGAAPNVAPSDVGGGGGTNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMT-PSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWKHVLEK------IVESYQIRYWAG-HDKEAAAHRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPSSDVIETFTRKAPPSQPPRIISSVR--SGSRYIITWDHVVALSNESTVTGYKILYRPDGQHDGKLFSTHK------HSIEVPIPRDGEYVVEVRAHSDGGDG---------VVSQVKISG-VSTLSSSLLSLLLPSLGFLVY-SEF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12860-1", "uniprot_id": "CNTN1_HUMAN", "id": "Q12860-1", "name": "Contactin-1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMWLLVSHLVIISITTCLAEFTWYRRYG--------------HGVSEEDKGFGPIFEEQPINTIYPEES--LEGKVSLNCRARASPFPVYKWR------MNNGDVDLTS---DRYSMVGGNLVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPER-TTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMP-STAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHKG-ELRLYDVTFE------------NAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVG-ENATMQCAASFDPALDLTFVWSFNGYVIDFNKE--NIHYQRNFMLDS---NGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQT-KTILSDDWKDAKTDPPIIEGN----MEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMS-PSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEK------IVESYQIRYWAA-HDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVR--SGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHK------HSIEVPIPRDGEYVVEVRAHSDGGDG---------VVSQVKISG-APTLSPSLLGLLLPAFGILVY-LEF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AXZ4-1", "uniprot_id": "CNT1A_DANRE", "id": "Q8AXZ4-1", "name": "Contactin-1a", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIPEAFQPRAMKHTTTVLMLALSSRFWSVCADFP--------------EVYGGESAGFGPVFEEQPLDTIYPEES--PEEKITLTCRTRANPPASYRWR------LNNAELVLAEGSDPHYSVSEGNLLISSPDKSKHAGNYTCVASNQYGSVTSRRARVQFGYLDMFSTDEREAVYVKEGQGAVLLCAPPPHFPEDLSFRWMLNEFPEFIPLDQRRFVSQSTGNLYISTVRSTDSGNYSCFVSSPAIAKSVFSKFIPLVPIAER-SLRKYPADIKVKSPDSWALLGQNVTLECFALGNPIPQIRWRKLDGVLPPLRHDVSMSGALLHLYSLQYEDEGLYECEADNSKGKDWHKTHLYVEGAPDWLEQISSSEVDIGGDYIMSCQASGKPKPHVHFLKNGHMYMKGHEVRFSRLGFE------------DSGMYQCVAENRHGVIHANAELRVFASAPSFQYNPVKPKLLGARNGRVVFECRPRAAPRPNITWSKGTELLHNSSRISIWLDGSLELLNISKSDEGKYTCFAENDRGRANSTGSLSITDATKITLAPSNADVSVG-EDARMECVASHDPGLDLTFIWSLDGHTINLQRD--AQHYQRKMDSASGTSSSELLITHTQLRHAGRYSCTAQTPVDNTTASAELVVRGPPGPPGGVRVDEVTSDSVRVLWSHGTDNLSPISRYTVQLRESAAQQDWRDAATSPVNVEGN----AEMATVVNLLPWTEYEFRVIATNTLGTGPPSEPSPKTTTREARPIVAPSDIGGGGGTSRELTITWTPVQSQYYYGSNFGYIIAFKPHNDPEWLRVTVTDPEAQKYVHKDPKIP-PSTRFEVKMKAFNSQGEGPFSNSAFIYSAQDVPAEAPIITEARALSATEAIVIWVPVQLP------TVERYQVRYWRESVENEASAQRVLVSSRENHTRLDNMKPDSHYLVEVRACNGAGYGPASQRNRIYTKKSPPSRPPKIISTKMHYSGTSINIAWEKVESLNNESTVAGYKVLYRQHGQPSGTLYTTEK------QSIDLPMRR-GEYLVEVRAHSEGGDG---------AVAQVRITGSAPAPALASALLLLPLLWTLML-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN14-1", "uniprot_id": "CONT_DROME", "id": "Q9VN14-1", "name": "Contactin", "aln": "MLAKIGLLASILVLNLVGQITPQFSENLPDPDPQSGQQPQNYQPSYNKDYSPRYNPLYTGQQSADPNQFDNTLVDGQSPNTYKGYYDGRAGGGGLGGNVVGPGNNLGGLGPQYDPFNRNSIGSAGVSYRDAYTDEDNFCPEHWVSFRQTCYRFIRSPKRNWAEAKKICKAHNADLINVDNVEKHSFILKNLILQNQRQNRFFISARQTGPLNWVNDDNTQLVQIEDSFSMDEQVPLENEDLHDNRFLVQNDLNNQNINNPNQFYNSLPGTVNQRNQNNLRGFIGPNQPYGDNRYVRDRVVYAFSKKRDRWMFMPAYEIELNLFICESKVLYSSDNVNIKLDDKRPYHYGLDINDMERIPRGPYFVKQPNDTTFDVNKNRLINDVTLSCLANGYPTPSYTWYREVYVDDRLEYQKIDPLAQDRYTISGGNLIIYEPKQALDQGAYHCVAENKFGRIRSESAHLNFGFIMEFN-LKRSAETSEMNWGKSIFCDPPQHYP-DVRYYWARDYFPNFVEEDQRVFVSRD-GALYFSFIETVDRANYSCTVQTLVSDTGRNGPFFPLRVTPNSNYQALIFANTFPKVFPEAPVAGDEIRLECMAFGYPIPSYNWTRQGLPLQRNAYTINYG-RVLIIQNATTNDNGEYSCTITNPRKTLMKSIYINIQMRPQFTIPLKDMIKDYNSDVTFICEAFAIPDANYTWYKNAERLDPANINRDRYIIQDNVLTIKFLEKDKDDAMYQCGAQNQLKTSFSSAQLRVLSMKPSFKKHPLESEVYAVYNGNTTIVCDPEAAPRPKFQWKKDGQVIGSGGHRRILPSGTLTISPTSRDDEGIYTCIASNQAGTDESHARVIVLQEIRFIETPPQRIVSKEHDLIFLHCEAAFDELLDIAYVWKHNGEVLKNNHDG-----TGRIIVDWN----RLTVHNTSMRDAGDYECVVKSAVNEISSKTSVSIEGAPGAPGGVQVIQISKTKAIIEWVDGSHNGRAIRYYNILG-RTNWNRTWVNVSTHVQAREVDRYTSRQQAEVVNLTPWSAYEFSVTAVNDLGIGTPSAPSPIYSTYEDKPYIAPRNVGGGGGKIGDLTITWDPLLPQEQHSHGIHYKVFWKLKGAIEWASDEIKKQDHMGVAVVNIPLNNYYTEYEVKVQAINSVGKGPESEIAVIHSAEDMPQVAPQKPIALAYNSTCFNVTWQPIDMSRENIRGKLIGHRLKYWKTTHQEEDSVYYLSRTTRNWALIVG-LQPDTYYFVKVMAYNAAGEGPESERFEERTYRKAPQKPPSSVHVYG-INPSTVRVVWRYVSPSQDEEPVEGYKVRIWESDQNMITANNTIVPIGQKLESYINNLTPGKSYNMRVLAYSNGGDGRMSSPTLHFQMGKTTRNGANTRHGHNINTALILSTLLLISTFLYTSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . . . * ** * :** :* : :. .::*.* :.. * . * * . : :*:: ***:* .*.: . * * *:*.*::* : * * :.**:: * .* : . * ::* ** *:* *: : * : ** *: *:* ***: * **:: :.: * .**** *.: .. . *:** .: *: : .: *::: ***:*:* *:*. .* : : :. . :* : . :*:* *.* * : . :. : :: *:: :.. * ..* * * . * . : **. . * : : : .**** *:* .:.*:*:::: *:*: :*:: :: .. .*.. : * *.***:*:: *.*. : : ...: * .*:* : ::.* * ***:*.*: * :* . : : : :: :* : :: : :.* *:.* **::::*. :* .:. ::: .: .* : ::.::.** * *..:: *:: ::.:.: :.*.**.***::: :: .. : * *:.* .* *.: .: . * :. * * : : * .*:* ** *** * *.* ** * ** ** .* * :** ::***** :***** *: : :. .: * : :* . ** :.. : . : : * ::**::*:*. *.** * *.* **:* * ** . . .:: * * : : ::::** ::* :. : :::: : : **: *:::* * *.** ** *: . * : .*.:** : . : :.* * . .:*..* ***: .* . .* .* : .* :.* *:*:**** :.:. .* . . *: *: ", "identical_positions": 238, "similar_positions": 324, "identity": "16.93%" }, { "cls_id": "homologset.agr.RGD:621301", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P27048-1", "uniprot_id": "RSMB_MOUSE", "id": "P27048-1", "name": "Small nuclear ribonucleoprotein-associated protein B", "aln": "---MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAERE------------EKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGLPPGRGTPMGMPPPGMRPPPPGMRGLL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P17136-1", "uniprot_id": "RSMB_RAT", "id": "P17136-1", "name": "Small nuclear ribonucleoprotein-associated protein B", "aln": "---MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAERE------------EKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGLL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14678-1", "uniprot_id": "RSMB_HUMAN", "id": "P14678-1", "name": "Small nuclear ribonucleoprotein-associated proteins B and B'", "aln": "---MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAERE------------EKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q05856-1", "uniprot_id": "RSMB_DROME", "id": "Q05856-1", "name": "Small nuclear ribonucleoprotein-associated protein B", "aln": "---MTIGKNNKMIQHLNYRVRIVLQDSRTFIGTFKAFDKHMNLILGDCEEFRKIRSKNSKVPERE------------EKRVLGFVLLRGENIVSLTVEGPPPPEEGLPRVPIPGAAPGPGIGRVAGRGMP--INLSAVPAGLQGPVRGVGGPAQQHMAPMGRGVPRAPMMGAPP-----PGMIPGGMPSMPGNMGRGAPPP-MRGPPPSMIR--GAP---PPGRG---GY-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40018-1", "uniprot_id": "RSMB_YEAST", "id": "P40018-1", "name": "Small nuclear ribonucleoprotein-associated protein B", "aln": "MSKIQVAHSSRLANLIDYKLRVLTQDGRVYIGQLMAFDKHMNLVLNECIEERVPKTQLDKLRPRKDSKDGTTLNIKVEKRVLGLTILRGEQILSTVVEDKP----------LLSKKERLVRDKKEKKQAQKQTKLRKEKEKKPGKIAKPNTANAKHTSSNSREIAQPSSSRYNGGNDNIGANRSRFNNEAPPQTRKFQPPPGFKRK-------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.:..:: : ::*::* : **.* :** : ********:* :* * * :.: .* *: ******:.:****:::* .**. * : . .: : : * : . . : :. .* .. . * : *** : ", "identical_positions": 41, "similar_positions": 50, "identity": "16.08%" }, { "cls_id": "homologset.agr.RGD:621302", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97527-1", "uniprot_id": "CNTN5_RAT", "id": "P97527-1", "name": "Contactin-5", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MASSWRLILFLSFTSCLSEYSEALSGLSTSYAALLRIKKSSTSSAFGSKSRPRYSSPSLGTLSVSPP---SWRG-------------------------------------AAQQYHSPVNLYHSPD----------------------------------------------------------------------------------AFRQDESVDYGPVFVQEPDDIIFPTDSD--EKKVALNCEVRGNPSPTYRWLRNG--------TEIDLESDYRYSMIDGTFIINNPSESRDSGLYQCLATNTFGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNAVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPTTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKSRLRKSQAVLEIPNLQLDDAGIYECTAENSRGKNSFRGQLQIYTYPHWVQKLNDTQLDSGSPLQWECKATGKPRPTYRWLKNGAPLLPQ----SRVDTANGVLAIHSVNQS-DAGMYQCLAENKYGAIYASAELKILASPPSFELNQVKKSIIVTKDREVLIECKPQGSPKPAISWRKGDKAVRGNKRIAILPDGSLRILNASKADEGKYICQGVNIFGSAEIIASVSVKEPTR-IELTPKRTELTVGESIVLNCKAMHDSSLDVTFYWTLKGQPIDFEKEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGVVIVEEITESTATLSWSPATDNHSPISSYNLQARSPFSLGWQTVKTVPEV----ITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSIPSRMIRTNEAVPKTAPSNVSGGSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSDASKFIYRDESVP-PLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPTAAPTDVTATSVSVSEIFVVWKHVKES----LGRPQGFEIGYWKDTEPEDSAETVRTRGNESFVMLTGLEGDTLYHLTVRAYNGAGYGPPSREVSATTKRHPPSEPPGNLRWE-QQGSQVSLGWEPVRPLANESEVMGYKVFYRQEGHSKGQVIETQKPQ------AVVPLPEAGVYIIEVRAYSEGGDG-TASSQIRVPSYAGGKITSAQSTLHSLSKWSS-VTLLLALMLPSSSW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P68500-1", "uniprot_id": "CNTN5_MOUSE", "id": "P68500-1", "name": "Contactin-5", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MASCWRLILFLSVTRWLSDYSEALSGLSTSYAALLRIKKSSTS-PFGSKSRPRFSSPSLGTISVSPP---SWRG-------------------------------------AAQQYHSPGNLYHSSD----------------------------------------------------------------------------------AFRQDESVDYGPVFVQEPDDVIFPTDSD--EKKVALNCEVRGNPSPSYRWLRNG--------TEIALESDYRYSLIDGTFIISNPSELRDSGLYQCLATNSFGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNAVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKSRLRKSQAVLEIPNLQLDDAGIYECTAENSRGKNSFRGQLQIFTYPHWVQKLNDTQLDSGSPLQWECKATGKPRPTYRWLKNGAPLLPQ----SRVDTVNGILAIQSVNQS-DAGMYQCLAENKYGAIYASAELKILASPPSFELNQVKKSIIVTKDRGVLIECEPQGSPKPAISWRKGDKAVRANKRIAILPDGSLRILNASKADEGKYICQGVNIFGSAEIIASLSVKEPTR-IELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEKEGGHFENIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGVVIVEEITESTATLSWSPATDNHSPISSYNLQARSPFSLGWQTVKTVPEV----ITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSIPSRMIRTNEAVPKTAPSNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVP-PLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPTAAPTDVTATSVSVSEIFVVWKHVKES----LGRPQGFEISYWKDTEPEDSVETVRTRGNESFVMLTGLEGNTLYHLTVRAYNGAGYGPPSREASTTTKRHPPREPPGNLRWE-QQGSQVSLGWEPVRPLANESEVMGYKVFYRQEGHSEGQVIETQKPQ------AVVPLPEAGVYIIEVRAYSEGGDG-TASSQIRVPSYSGGKITSAQSTLHSLSKWSS-VTLLLALMLPSSSW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94779-1", "uniprot_id": "CNTN5_HUMAN", "id": "O94779-1", "name": "Contactin-5", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MASSWKLMLFLSVTMCLSEYSKSLPGLSTSYAALLRIKKSSSSSLFGSKTRPRYSSPSLGTLSASSP---SWLG-------------------------------------AAQNYYSPINLYHSSD----------------------------------------------------------------------------------AFKQDESVDYGPVFVQEPDDIIFPTDSD--EKKVALNCEVRGNPVPSYRWLRNG--------TEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQ----SRVEMVNGVLMIHNVNQS-DAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTR-IELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEI----ITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVP-PLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKES----LGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWE-QQGSQVSLGWEPVIPLANESEVVGYKVFYRQEGHSNSQVIETQKLQ------AVVPLPDAGVYIIEVRAYSEGGDG-TASSQIRVPSYSGGKITSAQSTLHSLSTSSSSVTLLLALMIPSTSW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZW34-1", "uniprot_id": "CNTN5_DANRE", "id": "Q7ZW34-1", "name": "Contactin-5", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKADSSSSSSMSSRMRLRNSHG----VGSSSQ---DWSP-------------------------------------FSRHRYS---ALSSQE----------------------------------------------------------------------------------DYRSEESEEFGPVFIQEPDDAIFSLDSD--DKKIIMNCEARGNPVPTYSWLING--------TNVDTEADFRYSLIDGNLIIHNASEVIDYGRYQCRAENSIGIVLSRDALLQFAYLGPFSGKTRGAVSVREGQGVVLMCAPPSHSPEIIYSWVFNELPSFVAEDSRRFISQETGNLYIPKVQPSDVGSYVCQVKNTVTNARVLSPPTPLTLKTDGVMGEYEPKIEAHFPQTVLAAKGVTVRLECFALGNPVPTITWRKMSGNIPKKARLRKSQAVLEIPNIQLEDSGSYECKAENTRGGTAFRGHLQVYTLPQWISMINDTQLDSGEQLRWECRATGKPRPTYRWLRNGEPLSTQ----SRVEMVNGELTIHRLQQA-DSGMYQCIAENKYGAIYSSAELKILASAPMFNNNPVR--LIATVGKDVSLECRPRASPKPRISWRKNDRRLQPSRRIMLLRNNTLRIINSSRSDEGSYVCRAENQFGSAELTTVLLVKEPMR-VELSPLRVEVTVGESVVLSCKVTHDPSLDVSFLWLLNNQPLNTQQDGGHFEYIQTQSSTADLMIRSILLKHAGKYGCRAQTSTDSVLAEAELLVRGPPGPPGVVIVEEITASTATLSWSHGVDNHSPITTYNVQARSPVSLGWQTVKTDPDP----VTGSMESAMAVDLNPWVEYEFRVVATNSIGTGDPSPPSRAVRTKEAVPSVAPANVRGGNGRRHELVISWEPVSEEYQNGEGFGYIVAFRVNGTRGWKEKMVTSADSTTYKYRDETFP-PLTPFEVRVGVYNNKGDGPFSEVVTVFSAEGEPREPPSEVQAFAVSSSEIKVLWKPPSPG----LGRPQGYEVSFWKDVEQEELGKKKRTLGNETNMLLSGLDGNTQYLVSVKGFNSAGQGPSSTAVKISTKKNAPSLPPGNLMWI-QEGNNVSLSWDPVKARDNESEVIGYKVLLRQEGRGHSQVMRTPNSA------VVLTLPEGGTYIIEVRAVSEGGEG-AASAQVRVLTSSGVRAKNGQLSVQNSPPGLAWTALFLSLMVPSFPL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN14-1", "uniprot_id": "CONT_DROME", "id": "Q9VN14-1", "name": "Contactin", "aln": "MLAKIGLLASILVLNLVGQITPQFSENLPDPDPQSGQQPQNYQPSYNKDYSPRYNPLYTGQQSADPNQFDNTLVDGQSPNTYKGYYDGRAGGGGLGGNVVGPGNNLGGLGPQYDPFNRNSIGSAGVSYRDAYTDEDNFCPEHWVSFRQTCYRFIRSPKRNWAEAKKICKAHNADLINVDNVEKHSFILKNLILQNQRQNRFFISARQTGPLNWVNDDNTQLVQIEDSFSMDEQVPLENEDLHDNRFLVQNDLNNQNINNPNQFYNSLPGTVNQRNQNNLRGFIGPNQPYGDNRYVRDRVVYAFSKKRDRWMFMPAYEIELNLFICESKVLYSSDNVNIKLDDKRPYHYGLDINDMERIPRGPYFVKQPNDTTFDVNKNRLINDVTLSCLANGYPTPSYTWYREVYVDDRLEYQKIDPLAQDRYTISGGNLIIYEPKQALDQGAYHCVAENKFGRIRSESAHLNFGFIMEFN-LKRSAETSEMNWGKSIFCDPPQHYPDVRYYWARDYFPNFVEEDQRVFVSRD-GALYFSFIETVDRANYSCTVQTLVSDTGRNGPFFPLRVTPNSNYQALIFANTFPKVFPEAPVAGDEIRLECMAFGYPIPSYNWTRQGLPLQRNAYTINYGRVLIIQNATTNDNGEYSCTITNPRKTLMKSIYINIQMRPQFTIPLKDMIKDYNSDVTFICEAFAIPDANYTWYKNAERLDPANINRDRYIIQDNVLTIKFLEKDKDDAMYQCGAQNQLKTSFSSAQLRVLSMKPSFKKHPLESEVYAVYNGNTTIVCDPEAAPRPKFQWKKDGQVIGSGGHRRILPSGTLTISPTSRDDEGIYTCIASNQAGTDESHARVIVLQEIRFIETPPQRIVSKEHDLIFLHCEAAFDELLDIAYVWKHNGEVLKNNHDG----TGRIIVDWNRLTVHNTSMRDAGDYECVVKSAVNEISSKTSVSIEGAPGAPGGVQVIQISKTKAIIEWVDGSHNGRAIRYYNILGRTNWNRTWVNVSTHVQAREVDRYTSRQQAEVVNLTPWSAYEFSVTAVNDLGIGTPSAPSPIYSTYEDKPYIAPRNVGGGGGKIGDLTITWDPLLPQEQHSHGIHYKVFWKLKGAIEWASDEIKKQDHMGVAVVNIPLNNYYTEYEVKVQAINSVGKGPESEIAVIHSAEDMPQVAPQKPIALAYNSTCFNVTWQPIDMSRENIRGKLIGHRLKYWKTTHQEEDSVYYLSRTTRNWALIVGLQPDTYYFVKVMAYNAAGEGPESERFEERTYRKAPQKPPSSVHVYGINPSTVRVVWRYVSPSQDEEPVEGYKVRIWESDQNMITANNTIVPIGQKLESYINNLTPGKSYNMRVLAYSNGGDGRMSSPTLHFQMGKTTRNGANTRHGHNINTALILSTLLLISTFLYTSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. : .. : . :. .* :: . * .. * ** *:::*:* * :.: :.: :.* ..* * *:* * : :: :: **:: .*.:** :..: * * *:* * *..* : *..* *:*.:: *. .*.* : . . * ::* ** * *:: * *. : :*.** **.* *:*:: * **:. ::. * ..* * *:. *::: .* ** : :. . .. * :::**:*:* *:*: .* : . : :: : ** * * :* * *.* *.* ::: *:: ::* * .. : : *.* . * ..* * :*. * . .* :. * *: ::: * .**** *:*: : ::**:*::*: * * : :. : .. . . : * *..:*:* :.*:*..: : . : :* ..:* * :*: *** * * . * *: * : : * : * :* .* * . : :.* *:. .* **::: * :.: :. :.:* : . * ::. : .** * * .:::.:.: ::.: :.*.**.** * * :*: :.* :.* . .* .* **: .*: . * .*.* : . :.* .*:*.** *** *.*.* :* * ** ** * * * ** ** * .*: :*.*:*:*: : *:..*: * * :: :*: * .. :.. : : .. * :**:* . *. *.** *::..: ***. * .* . * : . : : * *: . . *: *..: :** . *: : ... :: **: :* * ..* .:*.** ** * . * : .* .*..: : . * : * * . :*. * **** :..:. . .* : *. . * :.* * *:**:* :*. ::. : :. :*:* . . ", "identical_positions": 251, "similar_positions": 349, "identity": "17.98%" }, { "cls_id": "homologset.agr.RGD:621303", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G5E829-1", "uniprot_id": "AT2B1_MOUSE", "id": "G5E829-1", "name": "Plasma membrane calcium-transporting ATPase 1", "aln": "--MGDMANNSVAYSGVKNSLKEANHDGDFGITLTELRALMELRSTDALRKIQESYGDVYG-ICTKLKTSPNEGLSGNPAD---LERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDNALCGEVSVGEE-EGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGG-------------------------EEEEKKDEK---KKEKKNKKQDGAIENRNKAKAQDG----AAMEMQPLKSEEGGDGDEKDKKKANLP---KKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEP---------------EAIPPNILSYLVTGISVNCAYTS--------------------------------------------KILPPEKEGGLPRHVGNKTECALLGFLLD--------LKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGS-----FRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAG---------EPEPEWDNENDVVTG----LTCIAVVGIEDPVRPEVPEAIKKCQRAGITVRMVTGDNINTARAIATKCGILH---PGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD--SPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHG--------------ERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEE--ELAEDVEEIDHAERELRRGQILWFRGLNRIQTQ-----------------------------IRVVNAFRSSL--YEGLEKPESRSSIHNFMT------------HPEFRIEDSEP-HIPLIDDTDAEDDAPTKRNSS------PPPSPNKNNNAVDS-GIHLTIEMNKSATSS---SPGSPLHSLETSL---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11505-3", "uniprot_id": "AT2B1_RAT", "id": "P11505-3", "name": "Plasma membrane calcium-transporting ATPase 1", "aln": "--MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYG-ICTKLKTSPNEGLSGNPAD---LERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDNALCGEVSVGEE-EGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGG-------------------------EEEEKKDEK---KKEKKNKKQDGAIENRNKAKAQDG----AAMEMQPLKSEEGGDGDEKDKKKANLP---KKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEP---------------EAIPPNILSYLVTGISVNCAYTS--------------------------------------------KILPPEKEGGLPRHVGNKTECALLGFLLD--------LKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGS-----FRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAG---------EPEPEWDNENDVVTG----LTCIAVVGIEDPVRPEVPEAIKKCQRAGITVRMVTGDNINTARAIATKCGILH---PGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD--SPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHG--------------ERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEE--ELAEDVEEIDHAERELRRGQILWFRGLNRIQTQ-----------------------------IRVVNAFRSSL--YEGLEKPESRSSIHNFMT------------HPEFRIEDSEP-LIPLIDDTDAEDDAPTKRNSS------PPPSPNKNNNAVDS-GIHLTIEMNKSATSS---SPGSPLHSLETSL---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P20020-3", "uniprot_id": "AT2B1_HUMAN", "id": "P20020-3", "name": "Plasma membrane calcium-transporting ATPase 1", "aln": "--MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYG-ICTKLKTSPNEGLSGNPAD---LERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDNALCGEVSVGEE-EGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGG-------------------------EEEEKKDEK---KKEKKNKKQDGAIENRNKAKAQDG----AAMEMQPLKSEEGGDGDEKDKKKANLP---KKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEP---------------EAIPPNILSYLVTGISVNCAYTS--------------------------------------------KILPPEKEGGLPRHVGNKTECALLGLLLD--------LKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGS-----YRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAG---------EPEPEWDNENDIVTG----LTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILH---PGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD--SPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHG--------------ERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEE--ELAEDVEEIDHAERELRRGQILWFRGLNRIQTQ-----------------------------IRVVNAFRSSL--YEGLEKPESRSSIHNFMT------------HPEFRIEDSEP-HIPLIDDTDAEDDAPTKRNSS------PPPSPNKNNNAVDS-GIHLTIEMNKSATSS---SPGSPLHSLETSL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0B2-1", "uniprot_id": "A0A8M9Q0B2_DANRE", "id": "A0A8M9Q0B2-1", "name": "Calcium-transporting ATPase", "aln": "-----MANN--SYSGVKNSVAEPNHNGEFGCSLKELRSLMELRGAEGLQKIQETYGDVNG-LCNRLKTSAVDGLSGQPSD---IEKRKAAFGQNFIPPKKPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYKPPDAGDKNCVKGTGGEP-EEEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFSVVRGGQVIQIHVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDAMLLSGTHVMEGSGKIVVTAVGVNSQTGIIFTLLGAGEDDDDE--------------------EEKEKKKEKER-KKEKKNKKQDGSVENRKKAKAQDG----AAMEMQPLNSDEGADGEEK--RKANLP---KKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVVLFVVDTFWVDKIPWDSGCIPIYIQFFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQVFIADKHYRKVPEP---------------DVVPASTMDLLIVGISVNCAYTT--------------------------------------------KIMSPEKEGGLNRQVGNKTECALLGFALD--------LKKDYQAVRNEIPEEKLYKVYTFNSVRKSMSTVLKNDDGS-----YRMFSKGASEILLKKCFKILTSTGEAKVFRPRDRDDMVKRVIEPMASEGLRTICLAYRDFPAS---------EGEPDWDNEADILTR----LTCVCVVGIEDPVRPEVPDAIRKCQRAGITVRMVTGDNLNTARAIATKCGILQ---VGDDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVVEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD--SPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAVYQLIIIFTLLFAGEKMFNIDSGRYADLHAPPSEHYTIVFNTFVMMQLFNEINARKIHG--------------ERNVFEGIFNNMIFCTIVFGTFVIQIVIVQFGGKPFSCVGLNIEQWLWCIFLGFGCLLWGQVISTIPTSRLTFLKTAGHGTQKEEIPDEELEELEDLDEIDHAERELRRGQILWFRGLNRIQTQMDVVSAFQSGISFQAAVRRQPSSGSQQHDIRVVNAFRSSLSPYEGLEKPESRTSIHNFMT------------HPEFRIEDSEP-HIPLIDDTDAEDDAPTKRNATPTPP--PPPSPNQNNNAVDS-GVHLFLDPSKSATPS---APGSPMHSLETSL---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32THH2-1", "uniprot_id": "A0AB32THH2_DANRE", "id": "A0AB32THH2-1", "name": "Calcium-transporting ATPase", "aln": "-----MAKN--SFRGSK-YKPEANHDGHFGCTLKELRSLMELRGTDGLQRIQECYGDVQG-LCSKLKSSPIEGLSGHPDD---IARRKEEFGKNFIPPKKPKTFLQLVWEALQDVTLIILEVAAIISLGLSFYKPPDAEREHCGRAAGGVEDEGEAEAGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQRFTVLRGGQVIQIPVSEIVVGDIAQVKYGDLLPADGVLIQGNDLKIDESSLTGESDHVKKTLDKDPILLSGTHVMEGSGKMLVTAVGVNSQTGIIFMLLGGGDDDDDDDEEKKEEKERKKREKEEKRREKEEKKKEKERKKKEQKDKKKNKKPDASDKKKEKDG----GTVEMEPLNSD---DGTEEEQKKAKIP---KKEKSVLQGKLTKLAVQIGKAGLFMSAITVLILVVLFLVDTFWIQGLPWIKDCTPIYIQFFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQVFIAGRHFKKVPEP---------------DLIPGNIMNLLVTGIGVNCAYTS--------------------------------------------KIMSAEKEGGLPRQVGNKTECALLGFVTD--------LRKDYQAIRCEYPEEKLYKVYTFNSVRKSMSTVLKNSDGS-----YRMFSKGASEILLKKCCKILTSNGDAKHFRPTDRDDMVTQVIEPMASEGLRTICLAYRDFLVS---------DGEPDWDNEGDILTG----LTCICVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILH---IGDDFLCLEGKEFNRRIRNELGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTVLEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD--SPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAVYQLTIIFTLLFAGEQIFDIDSGRNAPLHAPPSEHYTVVFNTFVLMQLFNEINARKIHG--------------ERNVFEGIFNNIIFCSILFGTFIIQFVIVQFGGKPFSCVGLSVEQWLWCVFLGFGSLLWGQVISTVPTRRLKFLITMGHGTKKEEIPEDELEEMEDLDEIDHAEMELRRGQVLWCRGLNRIQTQ-----------------------------IRVVNAFRDSMSPYDGLETPESRSSIHNFMS------------HPEFRIEDSEP-AIPLIDDTDPEEDAPTKRNAAPSPLPLVLSSPNQNNNAIDGRGFHHHIDLTKTILPP---TPGSPLHSLETSL---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q59DP9-1", "uniprot_id": "Q59DP9_DROME", "id": "Q59DP9-1", "name": "Calcium-transporting ATPase", "aln": "------------------MATIDGRPAQYGISLKQLRELMEHRGREGVMKIAE-NGGIHE-LCKKLYTSPNEGLSGSKAD---EEHRRETFGSNVIPPKPPKTFLTLVWEALQDVTLIILEVAALVSLGLSFYKPADEDAP--------VLQEEEEHHGWIEGLAILISVIVVVIVTAFNDYSKERQFRGLQNRIEGEHKFSVIRGGEVCQISVGDILVGDIAQVKYGDLLPADGCLIQSNDLKVDESSLTGESDHVKKGPDVDPMVLSGTHVMEGSGKMVVTAVGVNSQAGIIFTLLGAAVDE-----------------------QEAEIKKMKKEAKRANKQKNLTGENDGRSQIKGSQAPSQRETVTSEITKSESEGNHLPQSSSSGAAETGHKKEKSVLQAKLTKLAIQIGYAGSTIAVLTVIILIIQFCIKTFVIDEKPWKN----TYANNLVKHLIIGVTVLVVAVPEGLPLAVTLSLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYICEKLCKVLPTL---------------SDIPQHVGNLITMGISVNSAYTS--------------------------------------------NIMAGHNPGDLPIQVGNKTECALLGFVQG--------LGVKYQSIRDEITEDKFTRVYTFNSVRKSMGTVIPRPNGG-----YRLYTKGASEIIMKKCAFIYGHEGTLEKFTRDMQERLIREVIEPMACDGLRTISVAYRDFVPGKAAINEVHIDGEPNWDDEENIMTN----LTCLCVVGIEDPVRPEVPDAIRKCQRAGITVRMVTGDNINTARSIASKCGILR---PNDDFLILEGKEFNRRIRDSNGDIQQHLIDKVWPKLRVLARSSPTDKYTLVKGIIDSTVSENREVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSIAKFLQFQLTVNVVAVIVAFIGACAVQD--SPLKAVQMLWVNLIMDTLASLALATEFPTPDLLLRKPYGRTKPLISRTMMKNILGQALYQLIIIFGLLFVGDVILDIESGRGQELNAGPTQHFTIIFNTFVMMTLFNEINARKIHG--------------QRNVIEGLLTNPIFYTIWIFTMISQVLIIQYGKMAFSTKALTLDQWLWCIFFGIGTLVWGQLITSVPTRKLPKILSWGRG-HPEEYTDGMNLGEERFDSID-SDKKPRAGQILWIRGLTRLQTQ-----------------------------LRVIRAFRSTL---EDLNERRSMHSLHSLRSPRTGIPVAVGGGHPLYNFNLLNPNYIKHQQQQEPKLPPQTQLNVSSGMMS-PDISYIDEDPQQQQRTLHNGLTSQRSSMPSNVPSSNQSFSKIAQTLQQKIRGNIETKHSNGQNETRI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38929-1", "uniprot_id": "ATC2_YEAST", "id": "P38929-1", "name": "Calcium-transporting ATPase 2", "aln": "MSRQDENSALLANNENNKPSYTGNENGVYDNFKLSKSQLSDLHNPKSIRSFVRLFGYESNSLFKYLKTDKNAGISLPEISNYRKTNRYKNYGDNSLPERIPKSFLQLVWAAFNDKTMQLLTVAAVVSFVLGLYELWMQPPQ------YDPEGNKIKQVDWIEGVAIMIAVFVVVLVSAANDYQKELQFAKLNKKKE-NRKIIVIRNDQEILISIHHVLVGDVISLQTGDVVPADCVMISG-KCEADESSITGESNTIQKFP------------VDNSLRDFKKFNSIDSHN---------------------------------------HSKPLDIGDVNEDGNKIADCMLISGSRILSGLG---RGVITSVGINSVYGQTMTSLNAEPESTP---------LQLHLSQLADNISVYGCVSAIILFLVLFTRYLFYIIPEDGR-FHDLDPAQKGSKFMNIFITSITVIVVAVPEGLPLAVTLALAFATTRMTKDGNLVRVLRSCETMGSATAVCSDKTGTLTENVMTVVRGFPGNSKFDDSKSLPVSEQRKLNSKKVFEENCSSSLRNDLLANIVLNSTAFENRDYKKNDKNTNGSKNMSKNLSFLDKCKSRLSFFKKGNREDDEDQLFKNVNKGRQEPFIGSKTETALLSLARLSLGLQPGELQYLRDQPMEKFNIEKVVQTIPFESSRKWAGLVVKYKEGKNKKPFYRFFIKGAAEIVSKNCSYKRNSDDTLEEIN-EDNKKETDDEIKNLASDALRAISVAHKDFCECDSWPPEQLRDKDSPNIAALDLLFNSQKGLILDGLLGIQDPLRAGVRESVQQCQRAGVTVRMVTGDNILTAKAIARNCAILSTDISSEAYSAMEGTEFRKLTKNER--------IRILPNLRVLARSSPEDKRLLVETLKG-----MGDVVAVTGDGTNDAPALKLADVGFSMGISGTEVAREASDIILMTDDFSAIVNAIKWGRCVSVSIKKFIQFQLIVNITAVILTFVSSVASSDETSVLTAVQLLWINLIMDTLAALALATDKPDPNIMDRKPRGRSTSLISVSTWKMILSQATLQLIVTFILHFYGPELFFKKHEDEITSHQ-QQQLNAMTFNTFVWLQFFTMLVSRKLDEGDGISNWRGRISAANLNFFQDLGRNYYFLTIMAIIGSCQVLIMFFGGAPFSIARQTKSMWITAVLCGMLSLIMGVLVRICPDEVAVKVFPAAFVQRFKYVFGLEFLRKNHTGKHDDEEALLEESDSPESTAFY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . :. . * : :. ..: : . * : . * :. *:* . .* :*.* :* : **:** *** *::* *: :* :**::*: *.:*: : . .**** **:::*. **:*:* **:.** ** *:.: * :::: *:*..: * : .: ***: .:: **::*** :*.. . : ****:****: ::* ::.* : . . .::*: . * . . . :* .: . .: :* ** :*::** :*. * : : .::*. : . : : : . ::: :* .:**:*************::**::..:* **.**** * :*****.***:********* * ****: : . . . : .* :*.: ::: : * :*.*** ***.: * : : : . :. .*:* ** . *: :* :*:: ***:**: *:* . : : .. *: :*.:.**:*.:*.:** : :. ::: * ::**:**:*. * :::::*****:*********: **::** :*.** .: : :**.:*.: ::. :: *:********* ** **: : . :***********.**** *****:***:**:**:******* *:*::**:*: *** * ** **:**** **:.***::* .: .* * *.***:**:******:*:*****: * .:: *** **...*** : * **.:* ** : * * * * :: . : : :: ***** : :*. : :**:. : *.::.: * * :* *.:*: :* .** . . *: .:: *: *: * :: * : . : : : . * : . .: .: ", "identical_positions": 323, "similar_positions": 305, "identity": "22.38%" }, { "cls_id": "homologset.agr.RGD:621304", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2BEB4-1", "uniprot_id": "A0A8M2BEB4_DANRE", "id": "A0A8M2BEB4-1", "name": "Calcium-transporting ATPase", "aln": "------MGDLGNSTVEFHPKKPG-MDQGGHDGDFGVSVDELCSLMELRGAEALQKIQENYTNTET-LCHRLKTSPADGLSD---NPADLEKRRKVFGMNFIPPKQPKTFLELVWEALQDITLIILEIAAIISLGLSFYQPPGGDSEACVEVSEGAEDEGEADANWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQRFAVVRNSTVIQIPVAEMVVGDIAQVKYGDLLPADGVLIQGNDLKIDESSLTGESDHVRKSIDKDPMLLSGTHVMEGSGKMLVTAVGVNSQTGIIFTLLGAGEMEEEKKDCKKEVNSNSSTQFPSVEAKEHNIINGKQ-DGTLENNQNKAKKQDEAVAMEMQPLKSAEGGEVEEKEKKKASVP--KKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILMLYFVIKTFIVHKQPWLTECTPIYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQIYIGDQLFRDIPTPDQINPRTLE----------------LISSAIAVNCAYTS-------------------------------------------KIMPADKEGGLPKQVGNKTECALLGLVLD--------LKQDYQAVREQIPEELLYKVYTFNSVRKSMSTVIQMPDGS-----FRLYSKGASEILLKKCSFILSRDGEARAFRARDKDEMVKKVIEPMACDGLRTICIAYRELPA----------DPLPDWDNETDIVSN----LTCITVVGIEDPVRPEVPDAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIH---PGDDFLCMEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVVEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD--SPLKAVQMLWVNLIMDTFASLALATEPPTEALLLRKPYGRNNPLISRTMMKNILGHAVYQLVIIFTLLFAGERIFDIDSGRDAPLHSPPSEHYTIIFNTFVLMQLFNEINARKIHG--------------ERNVFDGIFSNPIFCSIVLGTFAIQIVIVQFGGKPFSCSPLNVEQWLWCLFVGMGELLWGQLISSVPTHQLKCLKEAGHGPAPDEMLDEDLAEDEEEIDYAERELRRGQILWFRGLNRIQTQMEVVSTFKRSGSFQGAVRRRSSVLSQLHD---------IRVVKAFRSSLYDGIERPESRNSIHDFQAHPEFIITDS-----VHNIPLIDETDVDDESERS-NHNH-VRVALRHPHSQPQAPQRPPRSRYPSRPLRQQSLPVTLNCNNNAAVESRVHLGTNGS-----GAPHTPASPLHSLETCL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58IK22-1", "uniprot_id": "A0AC58IK22_DANRE", "id": "A0AC58IK22-1", "name": "Calcium-transporting ATPase", "aln": "MSTTATMGDMANSTVEFYPKRGGGGAEANHAGDFGVSLDELRNLMELRGAEALQKIQESFTDVEG-LCQRLKSSTTDGLSD---NPTDLEKRRQTFGQNFIPPKKPKTFLQLVWEALQDVTLIILELAAIISLALSFYQPPGEDSEVCGKGAGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIELEQRFAVVRNGNVIQIPVAEMVVGDMAQVKYGDLLPADGVLVQGNDLKIDESSLTGESDHVRKSVEKDPMLLSGTHVMEGSGRMLVTAVGVNSQSGIIFTLLGAGEGEEEKKE-KKEDSSYS----PTATAKASGITNGKQPEAAVETNQNKAKKQDGAVAMEMQPLKSAEGGEVEEREKKKANVP--KKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIDTFVVGNMTWLPECTPIYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYINDQHFREIPDPSQISPNTLE----------------MIVNAISINCAYTS-------------------------------------------KIMPPDVEGGLPKQVGNKTECGLLGFLLD--------LKRDYAPVREQIPEEKLYKVYTFNSVRKSMSTVVQMPDGS-----FRLYSKGASEIVLKKCSSILGTNGEARNFRPRDRDEMVKKVIEPMACEGLRTICIGYRDLPG----------DPEPEWENEAEIVTD----LTCIAVVGIEDPVRPEVPDAIRKCQRAGITVRMVTGDNINTARAIASKCGIIQ---PGDDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVLEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD--SPLKAVQMLWVNLIMDTFASLALATEPPTEALLLRKPYGRNNPLISLTMMKNILGHGVYQLVIIFTLLFVGEKIFNIDSGRYAQLHSPPSEHYTIIFNTFVLMQLFNEINARKIHG--------------ERNVFDGIFANPIFCSIVLGTFGVQVVIVQFGGKPFSCAPLNVEQWLWCLFVGVGELLWGQVIATVPTSHLKCLKEAGHGPGTDEMTEDELAEDEEEIDHAERELRRGQILWFRGLNRIQTQMR--------------------------------------VVKAFRSSLYDGIEKPASRNSIHNFMAHPEFLINDY-----IHNIPLIDDTDIDEESEWS-RHNHQLHPAFRKPPPPP--VQQPQRSRPPPRPYRQYSLPATPNRNNNAIESTVYHLNLPTGPEGHWTSPPQKLNPLLALETSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q16720-1", "uniprot_id": "AT2B3_HUMAN", "id": "Q16720-1", "name": "Plasma membrane calcium-transporting ATPase 3", "aln": "------MGDMANSSIEFHPKPQQ-QRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSG-LCRRLKTSPTEGLAD---NTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKD-----------------------KKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAP--KKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILD----------------LLVHAISINSAYTT-------------------------------------------KILPPEKEGALPRQVGNKTECALLGFVLD--------LKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGG-----FRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSA----------GQEPDWDNENEVVGD----LTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQ---PGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD--SPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHG--------------ERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILWFRGLNRIQTQ--------------------------------------IRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDY-----THNIPLIDDTDVDENEER-----------LRAPPPPS------------------------PNQNNNAIDSGIYLTTHVTKSATSSVFSSSPGSPLHSVETSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64568-1", "uniprot_id": "AT2B3_RAT", "id": "Q64568-1", "name": "Plasma membrane calcium-transporting ATPase 3", "aln": "------MGDMANSSIEFHPKPQQ-QREVPHVGGFGCTLAELRSLMELRGAEALQKIQEAYGDVSG-LCRRLKTSPTEGLAD---NTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQGNDLKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKD-----------------------KKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANVP--KKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVDGRVWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILD----------------LLVHAISINSAYTT-------------------------------------------KILPPEKEGALPRQVGNKTECALLGFILD--------LKRDFQPVREQIPEDQLYKVYTFNSVRKSMSTVIRMPDGG-----FRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVKKIIEPMACDGLRTICIAYRDFSA----------IQEPDWDNENEVVGD----LTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQ---PGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD--SPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLTIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHG--------------ERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILWFRGLNRIQTQMEVVSTFKRSGSFQGAVRRRSSVLSQLHDVTNLSTPTHIRVVKAFRSSLYEGLEKPESKSCIHNFMATPEFLINDY-----THNIPLIDDTDVDENEER-----------LRAPPPPP------------------------PNQNNNAIDSGIYLTTHATKSATSSAFSSRPGSPLHSMETSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q59DP9-1", "uniprot_id": "Q59DP9_DROME", "id": "Q59DP9-1", "name": "Calcium-transporting ATPase", "aln": "-----------MATIDGRP------------AQYGISLKQLRELMEHRGREGVMKIAEN-GGIHE-LCKKLYTSPNEGLSG---SKADEEHRRETFGSNVIPPKPPKTFLTLVWEALQDVTLIILEVAALVSLGLSFYKPADEDAPVLQ--------EEEEHHGWIEGLAILISVIVVVIVTAFNDYSKERQFRGLQNRIEGEHKFSVIRGGEVCQISVGDILVGDIAQVKYGDLLPADGCLIQSNDLKVDESSLTGESDHVKKGPDVDPMVLSGTHVMEGSGKMVVTAVGVNSQAGIIFTLLGAAVDEQEAEIKKMKKEAKR---------ANKQKNLTGENDGRSQIKGSQAPSQRETVTSEITKSE-SEGNHLPQSSSSGAAETGHKKEKSVLQAKLTKLAIQIGYAGSTIAVLTVIILIIQFCIKTFVIDEKPWKN----TYANNLVKHLIIGVTVLVVAVPEGLPLAVTLSLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYICEKLCKVLPTLSDIPQHVGN----------------LITMGISVNSAYTS-------------------------------------------NIMAGHNPGDLPIQVGNKTECALLGFVQG--------LGVKYQSIRDEITEDKFTRVYTFNSVRKSMGTVIPRPNGG-----YRLYTKGASEIIMKKCAFIYGHEGTLEKFTRDMQERLIREVIEPMACDGLRTISVAYRDFVPGKAAINEVHIDGEPNWDDEENIMTN----LTCLCVVGIEDPVRPEVPDAIRKCQRAGITVRMVTGDNINTARSIASKCGILR---PNDDFLILEGKEFNRRIRDSNGDIQQHLIDKVWPKLRVLARSSPTDKYTLVKGIIDSTVSENREVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSIAKFLQFQLTVNVVAVIVAFIGACAVQD--SPLKAVQMLWVNLIMDTLASLALATEFPTPDLLLRKPYGRTKPLISRTMMKNILGQALYQLIIIFGLLFVGDVILDIESGRGQELNAGPTQHFTIIFNTFVMMTLFNEINARKIHG--------------QRNVIEGLLTNPIFYTIWIFTMISQVLIIQYGKMAFSTKALTLDQWLWCIFFGIGTLVWGQLITSVPTRKLPKILSWGRGHPEEYTDGMNLGEERFDSIDSDKKPRAGQILWIRGLTRLQTQLR--------------------------------------VIRAFRSTLEDLNER-RSMHSLHSLRSPRTGIPVAVGGGHPLYNFNLLNPNYIKHQQQQEPKLPPQTQLNVSSGMMSPDISYIDEDPQQQQRTLHNGLTSQRSSMPSNVPSSNQSFSKIAQTLQQKIRGNIETKHSNGQNETRI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38929-1", "uniprot_id": "ATC2_YEAST", "id": "P38929-1", "name": "Calcium-transporting ATPase 2", "aln": "-----MSRQDENSALLANNENNKPSYTGNENGVYDNFKLSKSQLSDLHNPKSIRSFVRLFGYESNSLFKYLKTDKNAGISLPEISNYRKTNRYKNYGDNSLPERIPKSFLQLVWAAFNDKTMQLLTVAAVVSFVLGLYELWMQPPQYDP------EGNKIKQVDWIEGVAIMIAVFVVVLVSAANDYQKELQFAKLNKKKE-NRKIIVIRNDQEILISIHHVLVGDVISLQTGDVVPADCVMISG-KCEADESSITGESNTIQKFP------------VDNSLRDFKKFNSIDSHNHSKPLDIGDVNED------------------------------GNKIADCMLISGSRILSGLGRGVITSVGINSVYGQTMTSLNAEPESTP--------LQLHLSQLADNISVYGCVSAIILFLVLFTRYLFYIIPEDGR-FHDLDPAQKGSKFMNIFITSITVIVVAVPEGLPLAVTLALAFATTRMTKDGNLVRVLRSCETMGSATAVCSDKTGTLTENVMTVVRGFPGNSKFDDSKSLPVSEQRKLNSKKVFEENCSSSLRNDLLANIVLNSTAFENRDYKKNDKNTNGSKNMSKNLSFLDKCKSRLSFFKKGNREDDEDQLFKNVNKGRQEPFIGSKTETALLSLARLSLGLQPGELQYLRDQPMEKFNIEKVVQTIPFESSRKWAGLVVKYKEGKNKKPFYRFFIKGAAEIVSKNCSYKRNSDDTLEEINEDNKKETDDEIKN-LASDALRAISVAHKDFCECDSWPPEQLRDKDSPNIAALDLLFNSQKGLILDGLLGIQDPLRAGVRESVQQCQRAGVTVRMVTGDNILTAKAIARNCAILSTDISSEAYSAMEGTEFRKLTKNER--------IRILPNLRVLARSSPEDKRLLVETLKG-----MGDVVAVTGDGTNDAPALKLADVGFSMGISGTEVAREASDIILMTDDFSAIVNAIKWGRCVSVSIKKFIQFQLIVNITAVILTFVSSVASSDETSVLTAVQLLWINLIMDTLAALALATDKPDPNIMDRKPRGRSTSLISVSTWKMILSQATLQLIVTFILHFYGPELFFKKHEDEITSHQ-QQQLNAMTFNTFVWLQFFTMLVSRKLDEGDGISNWRGRISAANLNFFQDLGRNYYFLTIMAIIGSCQVLIMFFGGAPFSIARQTKSMWITAVLCGMLSLIMGVLVRICPDEVAVKVFPAAFVQRFKYVFGLEFLRKNHTGKHDDEE-----------------------------------------------------------------ALLEESDSPESTAFY--------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: . :. . * : :. :.: .: . * : * :. *:: . :* : :* * :* : **:** *** *::* *: :* :**::*: *.:* . : . .**** **:::*: **:*:* **:.** ** *:.: * :::: *:*.. :.: ::***: .:: **::*** ::.. . : ****:****: ::* ::.* : . . .::*: :* : : . .: . . : * : . . . . ** :*::** :*. * . : : .::*. : : : : . ::: :* .:**:*************::**::..:* **.**** * :*****.***:********* * ****: : : . : :: : . *: . ::: * :*.*** .**.: * ::: : . :. .*:* ** . *: :* :*:: ***:**: *:*: . :. . : :. :: : :*.:.**:*.:.:::: . ::: : * ::**:**:*. * :::::*****:********** **::** :*.*: ..: : :**.:*.: ::.. :: *:********* ** **: : . :***********.**** *****:***:**:**:******* *:*::**:*: *** * ** **:**** **:.***::* .: .* * *.***:**:******:*:*****: * :: *** ** ..*** : * **.:. ** : * * * * :: . : : :: ***** : :*. : :**:. : *.::.: * * :* *::*: :* .** . . *: .:: *: *: * :: * : . . :: . . :.: :* : : * ", "identical_positions": 313, "similar_positions": 323, "identity": "21.75%" }, { "cls_id": "homologset.agr.RGD:621305", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6Q477-1", "uniprot_id": "AT2B4_MOUSE", "id": "Q6Q477-1", "name": "Plasma membrane calcium-transporting ATPase 4", "aln": "----------MTNPPGQSVSANTVAESHEGEFGCTLMDLRKLMELRGADAVAQISAHYGGVQEICTRLKTSPIEGLSG---NPADLEKRRLVFGKNVIPPKRPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPPGGDNEICGHIASSPEEEEEGETGWIEGAAILASVIIVVLVTAFNDWSKEKQFRGLQSRIELEQKFSIIRNGQLIQLPVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKTLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGASEEE-DDDDKKKKGKKQGAPENRNKAKTQDG---------------VALEIQPLNSQ-EGLDSEDKEKKIARIPKKEKSVLQGKLTRLAVQIGKAGLIMSVLTVVILILYFVVDNFVIQRREWLPECTPVYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGTHY-----------RQIPQPDVFPPKVLELIVNGISINCAYTSKIQPPE------------------------------------------------KEGGLPRQVGNKTECGLLGFVTD--------LKQDYQAVRNEVPEEKLFKVYTFNSVRKSMSTVIRKPEGG-----FRMFSKGASEIMLRRCDRILNKEGEIKSFRSKDRDNMVRNVIEPMASEGLRTICLAYRDFD-----------GTEPS----WDIEGEILTSLICIAVVGIEDPVRPEVPDAIAKCKRAGITVRMVTGDNVNTARAIATKCGILT---PKDDFLCLEGKEFNSLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTAGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD--SPLKAVQMLWVNLIMDTFASLALATEPPTESLLRRRPYGRNKPLISRTMMKNILGHAVYQLLIVFLLVFAGDTLFDIDSGRKAPLNSPPSQHYTIVFNTFVLMQLFNEINARKIHG--------------EKNVFAGVYRNIIFCTVVLGTFFCQIMIVELGGKPFSCTSLTMEQWMWCLFIGIGELLWGQVISAIPTKSLKFLKEAGHGSDKE---DISRDTEGMDEIDLAEMELRRGQILWVRGLNRIQTQIRVVKLFHN----------------------------------------NHEVAHKPKNRSSIHTFMTQPEYPADDELSQS-FLDIQEG-NPELVSKAGTSVLLLDGEAASHDNINNNAVDCHQVQIVASHSDSPLPS--LETPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64542-1", "uniprot_id": "AT2B4_RAT", "id": "Q64542-1", "name": "Plasma membrane calcium-transporting ATPase 4", "aln": "----------MTNPSGHNLPANSVAESYEGEFGCTLMDLRKLMELRAADAVTQISAHYGSVQEICARLKTSPVEGLSG---NPADLEKRRLVFGKNMIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPPGGENEICGHIVSNPEEDEEGETGWIEGAAILASVIIVVFVTAFNDWSKEKQFRGLQSRIELEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKTLDKDPMLLSGTHVMEGSGRMVVTAVGINSQTGIIFTLLGANEEE-DDE-KKKKGKKQGVSENRNKAKTQDG---------------VALEIQPLNSQ-EGLDSEEKEKKASKGPKKEKSVLQGKLTRLAVQIGKAGLIMSILTVLILILYFVVDNFVIQRRAWLPECTPVYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGTHY-----------RQIPKPDDLPPNVLDLIVNSICINSAYTSKILPPE------------------------------------------------KEGGLPRQVGNKTECGLLGFVTD--------LKQDYQAVRSEMPEEKLFKVYTFNSVRKSMSTVIRKPEGG-----FRVFSKGASEIMLRKCDRILNKEGGIVPFKTKDRDNMVRNVIEPMASEGLRTIGIAYRDFD-----------GEEPS----WENENEIFTGLVCIAVVGIEDPVRPEVPDAINKCKRAGITVRMVTGDNVNTARAIATKCGILT---PGDDFLCLEGKEFNRLIRNEKGEVEQEKLDKVWPRLRVLARSSPTDKHTLVKGIIDSNIGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFSGACITQD--SPLKAVQMLWVNLIMDTFASLALATEPPTDSLLRRRPYGRNKPLISRTMMKNILGHAVYQLGIVFLLVFAGDKLFDIDSGRKAPLNSPPSQHYTIVFNTFVLMQLFNEINSRKIHG--------------EKNVFAGVYRNIIFCSVVLGTFFCQILIVEVGGKPFSCTNLTMEQWMWCLFIGIGELLWGQVISAIPTKSLKFLKEAGHGSDKE---EISKDAEGLEEIDHAEMELRRGQILWVRGLNRIQTQIRVVKVFHS----------------------------------------FRDVIHKSKNQVSIHSFMTQPEYAADDEMSQS-FLNQEE--SPSLASKSRITKRLSDAETVSQNNTNNNAVDCHQVQIVASHPNSPLQS--QETPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P23634-1", "uniprot_id": "AT2B4_HUMAN", "id": "P23634-1", "name": "Plasma membrane calcium-transporting ATPase 4", "aln": "----------MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSG---NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDD-EGE-KKKKGKKQGVPENRNKAKTQDG---------------VALEIQPLNSQ-EGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHY-----------RQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPE------------------------------------------------KEGGLPRQVGNKTECALLGFVTD--------LKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGG-----FRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFD-----------DTEPS----WDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILT---PGDDFLCLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD--SPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNEINSRKIHG--------------EKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKE---EITKDAEGLDEIDHAEMELRRGQILWFRGLNRIQTQIDVINTFQTGASFKGVLRRQNMGQHLDVKLVPSSSYI---KVVKAFHSSLHESIQKPYNQKSIHSFMTHPEFAIEEELPRTPLLDEEEEENPDKASKFGTRVLLLDGEVTPYANTNNNAVDCNQVQLPQ--SDSSLQS--LETSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q59DP9-1", "uniprot_id": "Q59DP9_DROME", "id": "Q59DP9-1", "name": "Calcium-transporting ATPase", "aln": "---------------------MATIDGRPAQYGISLKQLRELMEHRGREGVMKIAEN-GGIHELCKKLYTSPNEGLSG---SKADEEHRRETFGSNVIPPKPPKTFLTLVWEALQDVTLIILEVAALVSLGLSFYKPADEDAPVL--------QEEEEHHGWIEGLAILISVIVVVIVTAFNDYSKERQFRGLQNRIEGEHKFSVIRGGEVCQISVGDILVGDIAQVKYGDLLPADGCLIQSNDLKVDESSLTGESDHVKKGPDVDPMVLSGTHVMEGSGKMVVTAVGVNSQAGIIFTLLGAAVDEQEAEIKKMKKEAKRANKQKNLTGENDGRSQIKGSQAPSQRETVTSEITKSESEGNHLPQSSSSGAAETGHKKEKSVLQAKLTKLAIQIGYAGSTIAVLTVIILIIQFCIKTFVIDEKPWK----NTYANNLVKHLIIGVTVLVVAVPEGLPLAVTLSLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYICEKLC-----------KVLPTLSDIPQHVGNLITMGISVNSAYTSNIMAGH------------------------------------------------NPGDLPIQVGNKTECALLGFVQG--------LGVKYQSIRDEITEDKFTRVYTFNSVRKSMGTVIPRPNGG-----YRLYTKGASEIIMKKCAFIYGHEGTLEKFTRDMQERLIREVIEPMACDGLRTISVAYRDFVPGKAAINEVHIDGEPN----WDDEENIMTNLTCLCVVGIEDPVRPEVPDAIRKCQRAGITVRMVTGDNINTARSIASKCGILR---PNDDFLILEGKEFNRRIRDSNGDIQQHLIDKVWPKLRVLARSSPTDKYTLVKGIIDSTVSENREVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSIAKFLQFQLTVNVVAVIVAFIGACAVQD--SPLKAVQMLWVNLIMDTLASLALATEFPTPDLLLRKPYGRTKPLISRTMMKNILGQALYQLIIIFGLLFVGDVILDIESGRGQELNAGPTQHFTIIFNTFVMMTLFNEINARKIHG--------------QRNVIEGLLTNPIFYTIWIFTMISQVLIIQYGKMAFSTKALTLDQWLWCIFFGIGTLVWGQLITSVPTRKLPKILSWGRGHPEEYTDGMNLGEERFDSID-SDKKPRAGQILWIRGLTRLQTQLRVIRAFRSTLEDLNERRSMHSLHSLRSPRTGIPVAVGGGHPLYNFNLLNPNYIKHQQQQEPKLPPQTQLNVSSGMMSPDISYIDEDPQQQQRTLHNGLTSQRSSMPSNVPSSNQSFSKIAQTLQQKIRGNIETKHSNGQNETRI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38929-1", "uniprot_id": "ATC2_YEAST", "id": "P38929-1", "name": "Calcium-transporting ATPase 2", "aln": "MSRQDENSALLANNENNKPSYTGNENGVYDNFKLSKSQLSDLHNPKSIRSFVRLFGY--ESNSLFKYLKTDKNAGISLPEISNYRKTNRYKNYGDNSLPERIPKSFLQLVWAAFNDKTMQLLTVAAVVSFVLGLYELWMQPPQYD------PEGNKIKQVDWIEGVAIMIAVFVVVLVSAANDYQKELQFAKLNKKKE-NRKIIVIRNDQEILISIHHVLVGDVISLQTGDVVPADCVMISG-KCEADESSITGESNTIQKFP------------VDNSLRDFKKFNSIDSHNHSKPLDIGDVNED-----GNKIADCMLISGSRILSGLGRG-----------------------VITSVGINSVYGQTMTSLNAEPESTPLQLHLSQLADNISVYGCVSAIILFLVLFTRYLFY-IIPEDGRFHDLDPAQKGSKFMNIFITSITVIVVAVPEGLPLAVTLALAFATTRMTKDGNLVRVLRSCETMGSATAVCSDKTGTLTENVMTVVRGFPGNSKFDDSKSLPVSEQRKLNSKKVFEENCSSSLRNDLLANIVLNSTAFENRDYKKNDKNTNGSKNMSKNLSFLDKCKSRLSFFKKGNREDDEDQLFKNVNKGRQEPFIGSKTETALLSLARLSLGLQPGELQYLRDQPMEKFNIEKVVQTIPFESSRKWAGLVVKYKEGKNKKPFYRFFIKGAAEIVSKNCSYKRNSDDTLEEINEDNK-KETDDEIKNLASDALRAISVAHKDFCECDSWPPEQLRDKDSPNIAALDLLFNSQKGLILDGLLGIQDPLRAGVRESVQQCQRAGVTVRMVTGDNILTAKAIARNCAILSTDISSEAYSAMEGTEFRKLTKNER--------IRILPNLRVLARSSPEDKRLLVETLKG-----MGDVVAVTGDGTNDAPALKLADVGFSMGISGTEVAREASDIILMTDDFSAIVNAIKWGRCVSVSIKKFIQFQLIVNITAVILTFVSSVASSDETSVLTAVQLLWINLIMDTLAALALATDKPDPNIMDRKPRGRSTSLISVSTWKMILSQATLQLIVTFILHFYGPELFFKKHEDEITSHQ-QQQLNAMTFNTFVWLQFFTMLVSRKLDEGDGISNWRGRISAANLNFFQDLGRNYYFLTIMAIIGSCQVLIMFFGGAPFSIARQTKSMWITAVLCGMLSLIMGVLVRICPDEVAVKVFPAAFVQRFK----------------------------YVFGLEFLR----------------------------------------------------KNHTGKHDDEEALLEESDSPESTAFY---------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :: : :* .* : :. .. :: :.: * *. *:* . :* :* * :* : **:** *** *::* *: :* :**::*: *.:*. :: . .**** **: :*::**:*:* **:.** ** *: : * ::*: :**..: :.: .::***: .:: **::*** :*.. . : ****:****: ::* ::.* : . . .::*: :* :: : . .: : * : . . : *.: ** :*::** :*. * : : ..:*: : . :: : : . ::: :* .:**:*************::**::..:* **.**** * :*****.***:********* * ****:.: : : . : : . : .: * . .*. . : * :*.*** .**.:. * : .:. :*. :. .*:* ** . *: :* :*.: ***:**: :.* . .. : . : *: :*.:.**:* :*::** . :. : : . * ::**:**:*. * ::: :*::**:*********: **::** :*.** . : : :**.**. ::.. :: *.********* ** **: : . :***********.**** *****:***:**:**:******* *:*::**:*: *** * ** **:**** **:.***::* .: .* * *.***:**:******:*:*****: * .:: *:* **...*** : * **.:* ** : * * * * :: . : * :: ***** : :*. : :**:. : *.: .: * * :: .*::*: * .** : . *: .:: *: *: * .: * . : . : :. ** :: : : :. . : . ", "identical_positions": 322, "similar_positions": 321, "identity": "23.2%" }, { "cls_id": "homologset.agr.RGD:621306", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63162-1", "uniprot_id": "RSMN_HUMAN", "id": "P63162-1", "name": "Small nuclear ribonucleoprotein-associated protein N", "aln": "---MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPERE------------EKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63164-1", "uniprot_id": "RSMN_RAT", "id": "P63164-1", "name": "Small nuclear ribonucleoprotein-associated protein N", "aln": "---MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPERE------------EKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63163-1", "uniprot_id": "RSMN_MOUSE", "id": "P63163-1", "name": "Small nuclear ribonucleoprotein-associated protein N", "aln": "---MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPERE------------EKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARGTPIGMPPPGMRPPPPGIRGPPPPGMRPPRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05856-1", "uniprot_id": "RSMB_DROME", "id": "Q05856-1", "name": "Small nuclear ribonucleoprotein-associated protein B", "aln": "---MTIGKNNKMIQHLNYRVRIVLQDSRTFIGTFKAFDKHMNLILGDCEEFRKIRSKNSKVPERE------------EKRVLGFVLLRGENIVSLTVEGPPPPEEGLPRVPIPGAAPGPGIGRVAGRGMP--INLSAVPAGLQGPVRGVGGPAQQHMAPMGRG-------VPRAPMMGAP---PPG------------MIPGGMPSMPGN---MGR------------GAPPPMRGPPPSMIRGAPPPGRGGY--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40018-1", "uniprot_id": "RSMB_YEAST", "id": "P40018-1", "name": "Small nuclear ribonucleoprotein-associated protein B", "aln": "MSKIQVAHSSRLANLIDYKLRVLTQDGRVYIGQLMAFDKHMNLVLNECIEERVPKTQLDKLRPRKDSKDGTTLNIKVEKRVLGLTILRGEQILSTVVEDKP----------LLSKKERLVRDKKEKKQAQKQTKLRKEKEKKPGKIAKPNTANAKHTSSNSRE-----------------------------------IAQPSSSRYNGGNDNIGAN------------RSRFNNEAPPQTRKFQPPPGFKRK--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9Y675-1", "uniprot_id": "SNURF_HUMAN", "id": "Q9Y675-1", "name": "SNRPN upstream reading frame protein", "aln": "---MERARDR-------LHLRRTTEQHVPEVEVQVKRRRTASLSNQECQLY----------PRRS------------QQQQVPVVDFQAE-LRQAFLAETP--------------RGG-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:. ::* :: : : .* :* *. ::: : .. ::.* : . : * ", "identical_positions": 6, "similar_positions": 25, "identity": "2.35%" }, { "cls_id": "homologset.agr.RGD:621307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04769-1", "uniprot_id": "PR7D1_MOUSE", "id": "P04769-1", "name": "Prolactin-7D1", "aln": "MLPSLIQPCSSGTLLMLLMSNLFLWEKVSSAPINASEAVLSDLKDLFDNATVLSGEMSKLGVIMRKEFFMNSFSSETFNKIILDLHKSTENITKAFNSCHTVPINVPETVEDVRKTSFEEFLKMVLHMLLAWKEPLKHLVTELSALPECPYRILSKAEAIEAKNKDLLEYIIRIISKVNPAIKENEDYPTWSDLDSLKSADKETQFFALYMFSFCLRIDLETVDFLVNFLKCLLLYDD-VCYSEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R005-1", "uniprot_id": "Q9R005_RAT", "id": "Q9R005-1", "name": "", "aln": "MPPSLIQSCSSGALLMLLMANLFLWEKVSSAPINASETTLNDLKDLFDNATVISGKMAELGFAMRKEFFSNSFSSDIFTNIILDLHKSKENIIKAFNSCHTVPINFPETTEDIRMTSFEEFLKMILQTLLAWKDPLQHLVTELSALPGCPYSILSKAKAIEAKNKDLLEYIKRIISMVNPAIKENEDYPIWSDLDSLQAADKEIQFFALYMFSFCLRSDLESLDFLVNFLKCLLLYNDNVCYSGF", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *****.****:******:*****************:.*.***********:**:*::**. ****** *****: *.:********.*** ************.***.**:* *********:*: *****:**:********** *** *****:************* **** ************ *******::**** ************* ***::*************:* **** *", "identical_positions": 201, "similar_positions": 28, "identity": "82.04%" }, { "cls_id": "homologset.agr.RGD:621308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHE4-1", "uniprot_id": "PHLP1_MOUSE", "id": "Q8CHE4-1", "name": "PH domain leucine-rich repeat-containing protein phosphatase 1", "aln": "----------------------------------------------------------------MEPAAAAPAQRLADPTGEDQA-LAAAAAE-----------------GGRCPDPALSAAAPSGGNGG--AAREEAPCEAPPGPLPGRAGGTGRRRRRGAPQPAAGGAAPVPAAGGGANSLLLKRGRLKRNLSAAAAASSSSSPSSASSAAG-----GLPASCSASASLCTRSLDRKTLLLKHR---QLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDTTAAEVAARLLQLG-------------------------------------------------------HKGGGVVKVLGYGP------PPAAAPAASDQTLDGEHGRDVEPPPSSGTVGAVRGPARAPPADLPLPGGAWTRCAPRISPAPSDSSPGELFAG--------GPGSPPRAPRP-ASDTESFSLSPSAESVSDRLDPYSSGGGGSSSSSEELEADPA--------MPHRPGRPAQPRP-PSPKTSALLQPKAPTGVDSTGVIAGEGPGDDKAMAAAAPDVPLSTSGRIRETVQKTS----PPSLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFGELWRVQEEGMDSEIGCLIRFYAGKPHSTGSSERIQLSGMYNVRKGKMQLP-------VNRWTRRQVILCGTCLIVSSVKDSVSGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQN------------FLRQTPTLPAARGLGELQRFTKLKSLNLSNNHLGAFPSAVCSIPTLAELNVSCNALREVPAAVGDMQNLQTFLLDGNFLQSLPAELESMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCVETLRLQALRRMPHIKHVDLRLNILRKLMADEVDFVQHVTQLDLRDNKLGDLDAMIFNNIEVLHCERNQLVTLNVCGYFLKALYASS---NELAQLDVYPVPNYLSYMDVSRNCLESVP-EWVCESRKLEVLDIGHNQICELPARLFCN--SSLRKLLAGHNRLARLPERLERTS-VEVLDVQHNQITELPPNLLMKADS-LRFLN----ASANKLETLPPATLSEETSSILQELYLTNNCLTDKCVPLLTGHPRLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIP-TTIMNCRRMHTVIAHSN-CIEVFPEVMQLPEVKCVDLSCNELSEIT-----LPENLPP-KLQELDLTGNPRLALDHKSLELLNN--------------------IRCFKIDQPSAG-DASGAPAVWS-HGYTEASG--VKNKLCVAALSVNNFRDNRE----ALYGVFDGD--RNVEVPYLLQCTMSDILAEELQKT-----KNEEEYMVNTFIVMQRKLG---------TAGQKLGGAAVLCHIKPDPVDLGGS-FTLTSANVGKCQTVLCRNGKPLSLSRSYIMSCEEERKRIKQHKAIITEDGKVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIDEAVEAVR-NVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSMPPPSPGIFPPSVNMVIKDRPSDGLGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPSGVLN---ESSPAYPNEQRCMLHP---VCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFSNGSRVEVEVDIHCSRAKEKERQQ---HLLQVPAEASDEGIVISANEDESGLSKKADFSAVGTIGRRRANGSVAPQERS------------------------------------------------HNVIEVAADAP-LRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQQQQQLPPPPQPPQP--QPQPQPQPQPQPQRHFQMDHLPDCYDTPL---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9WTR8-1", "uniprot_id": "PHLP1_RAT", "id": "Q9WTR8-1", "name": "PH domain leucine-rich repeat protein phosphatase 1", "aln": "----------------------------------------------------------------MEPAAAAPAQRLADPTGEDRAPAAAAAAE-----------------GGRSPDSVLSAAAPSGGNGG--AAREEAPCEAPPGPLPGRAGGTGRRRRRGVPQPAAGGAAPVTAAGGGANSLLLRRGRLKRNLS--AAASSSSSPSSASSAAG-----GLPASCSASASLCTRSLDRKTLLQKHR---QLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDTTAAEVAARLLQLG-------------------------------------------------------HKGGGVVKVLGHGP------PPAAAPAASDQTPATELGRDVEPPPSSSTVGAVRGPARAPPADLPLPGGAWTRCAPRVNPAPSDSSPGELFAG--------GPCSPSRAPRP-ASDTESFSLSPSAESVSDRLDPYSSGGG-SSSSSEELEADPATVLTGPSGPPHHPVRSSQPRP-PSPKTSALLQPKAPTGVDGTGLVVGEGPGDDKAVAAAAPGVPLWTPGRIRETVQKTSS---PPSLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFGELWRVQEEGMDSEIGCLIRFYAGKPHSTGSSERIQLSGMYNVRKGKMQLP-------VNRWTRRQVILCGTCLIVSSVKDSSSGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQN------------FLRQNPSLPAARGLGELQRFTKLKSLNLSNNHLGAFPSAVCSIPTLAELNVSCNALQEVPAAVGAMQNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCMETLRLQALRRMPHIKHVDLRLNILRKLITDEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLHCERNQLVTLNICGYFLKALYASS---NELVQLDVYPVPNYLSYMDVSRNCLESVP-EWVCESRKLEVLDIGHNQICELPARLFCN--SSLRKLLAGHNRLARLPERLERTS-VEVLDVQHNQIIELPPNLLMKADS-LRFLN----ASANKLETLPPATLSEETSSILQELYLTNNSLTDKCVPLLTGHPRLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIP-TTIMNCRRMHTVIAHSN-CIEVFPEVMQLPEVKCVDLSCNELSEIT-----LPENLPP-KLQELDLTGNPRLALDHKSLELLNN--------------------IRCFKIDQPSAG-DASGAPAVWS-HGYTEASG--VKNKLCVAALSVNNFRDNRE----ALYGVFDGD--RNVEVPYLLQCTMSDILAEELQKT-----KNEEEYMVNTFIVMQRKLG---------TAGQKLGGAAVLCHIRHDPVDLGGS-FTLTSANVGKCQTVLCRNGKPLSLSRSYTMSCEEERKRIKQHKAIITEDGKVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVR-NVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSVGGSMPPPSPGIFPPSVSMVIKDRPSDGLGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPSGALS---ESSPAYPSEQRCMLHP---VCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFSNGSRVEVEVDIHCSRAKEKERQQ---HLLQVPAEASDEGIVISANEDESGLSKKTDISAVGTIGRRRANGSVPPQERS------------------------------------------------HNVIEVATDAP-LRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQQQQQQQQQQQPPPPPQPPQAQAQAQAQAQRPFQMDHLPDCYDTPL---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60346-1", "uniprot_id": "PHLP1_HUMAN", "id": "O60346-1", "name": "PH domain leucine-rich repeat-containing protein phosphatase 1", "aln": "----------------------------------------------------------------MEPAAAATVQRLPELGREDRASAPAAAAAAAAAAAAAAAALAAAAGGGRSPEPALTPAAPSGGNGSGSGAREEAPGEAPPGPLPGRAGGAGRRRRRGAPQPIAGGAAPVPGAGGGANSLLLRRGRLKRNLSAAAAAASSSSSSSAAAASHSPGAAGLPASCSASASLCTRSLDRKTLLLKHR---QTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDTTAGEVAARLLQLG-------------------------------------------------------HKGGGVVKVLGQGPGAAAAREPAEPPPEAGPRLAPPEPRDSEVPPARSAPGAFGGPPRAPPADLPLPVGGPGGWSRRASPAPSDSSPGEPFVG--------GPVSSPRAPRPVVSDTESFSLSPSAESVSDRLDPYSSGGG-SSSSSEELEADAASAPTGVPGQPRRPGHPAQPLPLPQTASSPQPQQKAPRAIDSPGGAVREGSCEEKAAAAVAPGGLQSTPGRSGVTAEKAPPPPPPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFGELWRVQEEGMDSEIGCLIRFYAGKPHSTGSSERIQLSGMYNVRKGKMQLP-------VNRWTRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQN------------FLRQNPSLPAARGLNELQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLHCERNQLVTLDICGYFLKALYASS---NELVQLDVYPVPNYLSYMDVSRNRLENVP-EWVCESRKLEVLDIGHNQICELPARLFCN--SSLRKLLAGHNQLARLPERLERTS-VEVLDVQHNQLLELPPNLLMKADS-LRFLN----ASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIP-TTIMNCRRMHTVIAHSN-CIEVFPEVMQLPEIKCVDLSCNELSEVT-----LPENLPP-KLQELDLTGNPRLVLDHKTLELLNN--------------------IRCFKIDQPSTG-DASGAPAVWS-HGYTEASG--VKNKLCVAALSVNNFCDNRE----ALYGVFDGD--RNVEVPYLLQCTMSDILAEELQKT-----KNEEEYMVNTFIVMQRKLG---------TAGQKLGGAAVLCHIKHDPVDPGGS-FTLTSANVGKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITEDGKVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVR-NVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNMVIKDRPSDGLGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPPGALS---ENSPAYPSEQRCMLHP---ICLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVEVDIHCSRAKEKEKQQ---HLLQVPAEASDEGIVISANEDEPGLPRKADFSAVGTIGRRRANGSVAPQERS------------------------------------------------HNVIEVATDAP-LRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQQ---------PPPP-------PQLQPQLPRHYQLDQLPDYYDTPL---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ07-1", "uniprot_id": "PHLPP_DROME", "id": "Q9VJ07-1", "name": "Protein phosphatase PHLPP-like protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKATR----KQADPYKSKLKVSASHSGPHP-----------LPVEVTAAEEEQAATFGQTSPQKLSLKGSQLG------------------------------------GSILIGN------------------------------------YNYLTQLEVCENEMEVLDLSSLAQLETLKCSRNKLMELIINGTNLQTLVADHNYLHNISTTNTHPVPLKLQRIDISHNNFSELP-NWVGACASLTAINASHNRLNNVAVLLRNYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPDNFFAVTHARLETLN----VSCNKLSTLP--RYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEILVLSGNMLQQLP-EEVATLGQLRVLRCCNN-LLLCTPQLAKLAMLKVLDLSHNHLDRVN-----LLALVPSRNLKYLDLSGNLQLQVDEQQFKVCQSQSQRHWSLVDVSGN--NRAALPTTKIRQVSAQRNQNKTSGPWT-MGFAETPGSGDCRKLSVYQLRAANYGGSDE----ALYGMFEALEGRGRAAQEMSHLVPDLMKQEQMVKD-----SAVRDYMKFTLLAAQQQCG---------SVRSAALFHLTRTRAPSKVRPLKSKRYVLRMASTGGLDAYLIRRTSQLRLTKPDVIQKDQIHS----------------------------------MPDPHVLELILSNDDEYLVVGNAQLWSVMDIDRAAREIR-KEENSLLAAKRLVDIAQSFAAAESLSVIVVRFRHLGTDVDHLIRELKQSVRKKPQPVSLPLSSGSVCKRTCCDRSNACRHRAIEQEPLAGRSSPSGQSDRDLLAKDKDDEFVLA---HARVLQEEQQLEMLDETESVSESVLSEEQFKCWEYMLEQNTQLLFDKELNTISKSFTKQRTVPNAIMAATVLPERNDFTS---NLMRTVTNKFISTSTPQLPQPITTSVPLGSYHQVKQAPPGHFGSALSFQQAH------------------------------------------------SYGYNLFDAKPRPKFHGGTVKRSAGPNSAYFGSLQRLMPYNFEYDFAVTQERERNILDEE----------------EHDDDDFNEHESRMRKYWGVATTEL---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08678-1", "uniprot_id": "CYAA_YEAST", "id": "P08678-1", "name": "Adenylate cyclase", "aln": "MSSKPDTGSEISGPQRQEEQEQQIEQSSPTEANDRSIHDEVPKVKKRHEQNSGHKSRRNSAYSYYSPRSLSMTKSRESITPNGMDDVSISNVEHPRPTEPKIKRGPYLLKKTLSSLSMTSANSTHDDNKDHGYALNSSKTHNYTSTHNHHDGHHDHHHVQFFPNRKPSLAETLFKRFSGSNSHDGNKSGKESKVANLSLSTVNPAPANRKPSKDSTLSNHLADNVPSTLRRKVSSLVRGSSVHDINNGIADKQIRPKAVAQSENTLHSSDVPNSKRSHRKSFLLGSTSSSSSRRGSNVSSMTNSDSASMATSGSHVLQHNVSNVSPTTKSKDSVNSESADHTNNKSEKVTPEYNENIPENSNSDNKREATTPTIETPISCKPSLFRLDTNLEDVTDITKTVPPTAVNSTLNSTHGTETASPKTVIMPEGPRKSVSMADLSVAAAAPNGEFTSTSNDRSQWVAPQSWDVETKRKKTKPKGRSKSRRSSIDADELDPMSPGPP-SKKDSRHHHDRKDNESMVTAGDSNSSFVDICKENVPNDSKTALDTKSVNRLKSNLAMSPPSIRYAPSNLDGDYDTSSTSSSLPSSSISSEDTSSCSDSSSYTNAYMEANREQDNKTPILNKTKSYTKKFTSSSVNMNSPDGAQSSGLLLQDEKDDEVECQLEHYYKDFSDLDPKRHYAIRIFNTDDTFTTLSCTPATTVEEIIPALKRKFNITAQGNFQISLKVGKLSKILRPTSKPILIERKLLLLNGYRKSDPLHIMGIEDLSFVFKFLFHPVTPSHFTPEQEQRIMRSEFVHVDLRNMDLTTPPIIFYQHTSEIESLDVSNNANIFLPLEFIESSIKLLSLRMVNIRASKFPSNITKAYKLVSLELQRNFIRKVPNSIMKLSNLTILNLQCNELESLPAGFVELKNLQLLDLSSNKFMHYPEVINYCTNLLQIDLSYNKIQSLP---QSTKYLVKLAKMNLSHNKLNFIGDLSEMTDLRTLNLRYNRISSIKTNASN-LQNLFLTDNRISNFEDTLPKLRALEIQENPITSISFKDFYPKN--MTSLTLNKAQLSSIPGELLTKLSFLEKLELNQNNLTRLPQEISKL--TKLVFLSVARNKLEYIPPELSQLKSLRTLDLHSNNIRDFVDGMENLELTSLNISSNAFGNSSLENSFYHNMSYGSKLSKSLMFFIAADNQFDDAMWPLFNCFVNLKVLNLSYN---NFSDVSHMKLESITELYLSGNKLTTLSGDTVLKWSSLKTLMLNSNQMLSLPAELSNLSQLSVFDVGANQLKYNISNYHYDWNWRNNKELKYLNFSGNRRFEIKSFISHDIDADLSDLTVLPQLKVLGLMDVTLNTTKVPDENVNFRLRTTASIINGMRYGVADTLGQRDYVSSRDVTFERFRGNDDECLLCLHDSKNQNADYGHNISRIVRDIYDKILIRQLERYGDETDDNIKTALRFSFLQLNKEINGMLNSVDNGADVANLSYADLLSGACSTVIYIRGK--KLFAANLGDCMAILSKNNGDYQTLTKQHLPTKREEYERIRISGGYVNNGKLDGVVDVSRAVGFFDLLPHIHASPDISVVTLTKADEMLIVATHKLWEYMDVDTVCDIARENSTDPLRAAAELKDHAMAYGCTENITILCLALYENIQQQNRFTLNKNSLMTRRSTFEDTTLRRLQPEISPPTGNLAMVFTDIKSSTFLWELFPNAMRTAIKTHNDIMRRQLRIYGGYEVKTEGDAFMVAFPTPTSGLTWCLSVQLKLLDAQWPEEITSVQDGCQVTDRNGNIIYQGLSVRMGIHWGCPVPELDLVTQRMDYLGPMVNKAARVQGVADGGQIAMSSDFYSEFNKIMKYHERVVKGKESLKEVYGEEIIGEVLEREIAMLESIGWAFFDFGEHKLKGLETKELVTIAYPKILASRHEFASEDEQSKLINETMLFRLRVISNRLESIMSALSGGFIELDSRTEGSYIKFNPKVENGIMQSISEKDALLFFDHVITRIESSVALLHLRQQRCSGLEICRNDKTSARSNIFNVVDELLQMVKNAKDLST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*.: : . .* * :. . .. : . : *. . * : * : *:: *.: :. :: * *:: : *::* . .: : :* : : :.: :..:* : : * :: .:*.: .:. : :.* * . * * : . . :. *::: *:: .: .: : *. . *. : . .: * : :.* : * : .*::*:::** :. : .: : :*** * :. : . ::.: .* : .:: :*. :. .*:. *.*. :*: *:::** :: :. . : : *: : .. :.. . : : :. : .: .. : .*:. : . : : . : .:: : . . : ::: ::: . : .. * *. * : * :. : .. . *.: : *: ** :::.. **. :.:: . * : :.* ** .* * ::.. :.:: : : : . . : . . . . . . : . : . : : . : :: : . . : : : * : .: . . * : . . : . : . . :: :. : . . . : : . : : . : : : * ", "identical_positions": 65, "similar_positions": 272, "identity": "3.19%" }, { "cls_id": "homologset.agr.RGD:621309", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62745-1", "uniprot_id": "RHOB_HUMAN", "id": "P62745-1", "name": "Rho-related GTP-binding protein RhoB", "aln": "-----MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQKRYGSQNGCIN--------CCKVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62747-1", "uniprot_id": "RHOB_RAT", "id": "P62747-1", "name": "Rho-related GTP-binding protein RhoB", "aln": "-----MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQKRYGSQNGCIN--------CCKVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62746-1", "uniprot_id": "RHOB_MOUSE", "id": "P62746-1", "name": "Rho-related GTP-binding protein RhoB", "aln": "-----MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQKRYGSQNGCIN--------CCKVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48148-1", "uniprot_id": "RHO1_DROME", "id": "P48148-1", "name": "Ras-like GTP-binding protein Rho1", "aln": "-----MTTIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRDLAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQVKKRKKTRCLL--------L----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06780-1", "uniprot_id": "RHO1_YEAST", "id": "P06780-1", "name": "GTP-binding protein RHO1", "aln": "MSQQVGNSIRRKLVIVGDGACGKTCLLIVFSKGQFPEVYVPTVFENYVADVEVDGRRVELALWDTAGQEDYDRLRPLSYPDSNVVLICFSIDLPDSLENVQEKWIAEVLHFCQGVPIILVGCKVDLRNDPQTIEQLRQEGQQPVTSQEGQSVADQIGATGYYECSAKTGYGVREVFEAATRASLMGKSKTNGKAKKNTTEKKKKKCVLL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**:***:*****************.:****************:****::************************::*:*:***:* ******: *** .** *** .******. * ***.* :. :* : *:** .::*:::* :* * * *****: ***:***:****:* : .: . ", "identical_positions": 122, "similar_positions": 38, "identity": "58.37%" }, { "cls_id": "homologset.agr.RGD:621310", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P84095-1", "uniprot_id": "RHOG_HUMAN", "id": "P84095-1", "name": "Rho-related GTP-binding protein RhoG", "aln": "MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKRGRSCILL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P84096-1", "uniprot_id": "RHOG_MOUSE", "id": "P84096-1", "name": "Rho-related GTP-binding protein RhoG", "aln": "MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKRGRSCILL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32PX6-1", "uniprot_id": "Q32PX6_RAT", "id": "Q32PX6-1", "name": "Rho-related GTP-binding protein RhoG", "aln": "MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKRGRSCILL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1LY89-1", "uniprot_id": "Q1LY89_DANRE", "id": "Q1LY89-1", "name": "Rho-related GTP-binding protein RhoG", "aln": "MQNIKCVVVGDGAVGKTCLLISFTTNAFPKEYVPTVFDNYSAQVLVDSKTVSLNLWDTAGQEEYDRLRTLSYPQTNIFIICFSVTSPPSFENVKLKWHPEVFEHCPNVPILLVGTKKDLRDDPEELKKLKEKGLSVVSQQQGTALARQIHARKYMECSALSQDGVKEVFTEAARIFLHPKQPSSKKSCVLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.******************.:*********:********** **.:**.************************:*:****::****:***: ****** .***:************* :*: *::***:* : :: *** ***:**** :*:*****.********:**.* .*:*. . :**:**", "identical_positions": 140, "similar_positions": 35, "identity": "73.3%" }, { "cls_id": "homologset.agr.RGD:621311", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80XR2-1", "uniprot_id": "AT2C1_MOUSE", "id": "Q80XR2-1", "name": "Calcium-transporting ATPase type 2C member 1", "aln": "--------------------------------------------------------------------------MKVARFQKIPNVENE---------TMIP--VLTSKRASELAVSEVAGLLQADLQNGLNKS-EVSHRRAFHGWNEFDISEDEPLWKKYISQFKNP-LIMLLLASAVISILMRQFDDAVSITVAIVIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSVDESSLTGETAPCSKVTAPQP-AAN-GDLAS-------RSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHILTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--TLMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYNS--KGQTLALTQQQRDLYQQEKARMGSAGLRVLALASGPE-----------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAIAIASR----------------------------------------------------------LGLYSKTSQSVSGEEVDTMEVQHLSQIVPKVAVFYRASPRHKMKIIKSLQKNGAVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVI--TPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVSEIIKKVERSREKVQKNAGSASSSFLEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64566-1", "uniprot_id": "AT2C1_RAT", "id": "Q64566-1", "name": "Calcium-transporting ATPase type 2C member 1", "aln": "--------------------------------------------------------------------------MKVARFQKIPNVENE---------TMIP--VLTSKRASELAVSEVAGLLQADLQNGLNKS-EVSHRRAFHGWNEFDISEDEPLWKKYISQFKNP-LIMLLLASAVISVLMRQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQP-AATNGDLAS-------RSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHILTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--TLMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYNS--KGQTLALTQQQRDLYQQEKAQMGSAGLRVLALASGPD-----------LGQLTLLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAIAIASR----------------------------------------------------------LGLYSKTSQSVSGEEVDTMEVQHLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVI--TPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVSEIIKKVERSREKTQKNTTSTPSSFLEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P98194-1", "uniprot_id": "AT2C1_HUMAN", "id": "P98194-1", "name": "Calcium-transporting ATPase type 2C member 1", "aln": "--------------------------------------------------------------------------MKVARFQKIPNGENE---------TMIP--VLTSKKASELPVSEVASILQADLQNGLNKC-EVSHRRAFHGWNEFDISEDEPLWKKYISQFKNP-LIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQP-AATNGDLAS-------RSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--TLMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQS--KGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPE-----------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASR----------------------------------------------------------LGLYSKTSQSVSGEEIDAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVI--TPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVERSREKIQKHVSSTSSSFLEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9PG15-1", "uniprot_id": "M9PG15_DROME", "id": "M9PG15-1", "name": "P-type Ca(2+) transporter", "aln": "MSKTPKPLTSKRRTSPASPGSTVLIESPTTSSGVRNRRSKIKGVDSKPNPQRTISHVKDSRAVPQNVKPGKVADMKDCKEPDEDNVDQQNGNIIQTGLTLTPEMLLSTSESSTHSASEVAGRLQVDVRTGLKWT-EAKYRAKIIGHNELLLVAEDPTWKKYIEQFRNP-LILLLLGSALVSVIMKQFDDAVSITIAILIVVTVAFIQEYRSEKSLEELKKLVPPECHCLREGRLDTFLARELVPGDIVHLNVGDRVPADVRLFEAVDLSIDESSFTGETEPARKITDVLLNNTNVKDHSN-------MKNIAFMGTLVRCGNGKGIVVSTGERSEFGEVFKMMQAEEAPKTPLQKSMDILGAQLSFYSFLIIGVIMLLGWLQGKPLSEMFNISVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNSIVKKLPTVETLGCVNVICSDKTGTLTKNEMTATIIITSDGYMADVTGAGYNDQGEIHIRHCNNVEMAKTNITNLLEIGAVCNNAYIQNG--TLLGQPTEGALVAVAMKNGMYATAENYVRIQEYPFSSEQKMMAVKCIHKYNNNKEEIFFAKGALETLLPQCTKYQF--GTQTVPLTKQNEAEFLAEAYEIGRKGLRVLALAKGRS-----------MQDLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAIDPSRRLQAVPTHAIPAWPTAGGVPLCSASACCSTNCLENAMKEIYLTALAQQGLPLVTANLIGIDTIHHQTLSGQEMDQMNEHQLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIALATLMDIANPLNAMQILWINIIMDGPPAQSLGVEPVDHDVLKQKPRNVKQPMITKSVVVNVLLSASIIVLGTLWVFQREMADGTLGKTKRDTTMTFTCFVFFDMFNALSCRSQTKSVFTIGLTTNRMFLLAVAFSIIGQMLVVYFPPLQMVFQTEALTPYDIFFLVSLTSSVLVVSEIKKWFERTMERKMYSTRSELDFV---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P13586-1", "uniprot_id": "ATC1_YEAST", "id": "P13586-1", "name": "Calcium-transporting ATPase 1", "aln": "--------------------------------------------------------------MSDNPFNASLLDEDSNREREILDATAE---------ALSK--PSPSLEYCTLSVDEALEKLDTDKNGGLRSSNEANNRRSLYGPNEITVEDDESLFKKFLSNFIEDRMILLLIGSAVVSLFMGNIDDAVSITLAIFIVVTVGFVQEYRSEKSLEALNKLVPAECHLMRCGQESHVLASTLVPGDLVHFRIGDRIPADIRIIEAIDLSIDESNLTGENEPVHKTSQTIE-KSSFNDQPNSIVPISERSCIAYMGTLVKEGHGKGIVVGTGTNTSFGAVFEMMNNIEKPKTPLQLTMDKLGKDLSLVSFIVIGMICLVGIIQGRSWLEMFQISVSLAVAAIPEGLPIIVTVTLALGVLRMAKRKAIVRRLPSVETLGSVNVICSDKTGTLTSNHMTVSKLWCLDSMSNKLNVLSLDKNKKTKNSNGNLKNYLTEDVRETLTIGNLCNNASFSQEHAIFLGNPTDVALLEQLANFEMPDIRNTVQKVQELPFNSKRKLMATKILNPVDN--KCTVYVKGAFERILEYSTSYLKSKGKKTEKLTEAQKATINECANSMASEGLRVFGFAKLTLSDSSTPLTEDLIKDLTFTGLIGMNDPPRPNVKFAIEQLLQGGVHIIMITGDSENTAVNIAKQIG--------------------------------------------------------IPVIDPKLSVLSGDKLDEMSDDQLANVIDHVNIFARATPEHKLNIVRALRKRGDVVAMTGDGVNDAPALKLSDIGVSMGRIGTDVAKEASDMVLTDDDFSTILTAIEEGKGIFNNIQNFLTFQLSTSVAALSLVALSTAFKLPNPLNAMQILWINILMDGPPAQSLGVEPVDHEVMKKPPRKRTDKILTHDVMKRLLTTAACIIVGTVYIFVKEMAEDGK-VTARDTTMTFTCFVFFDMFNALACRHNTKSIFEIGFFTNKMFNYAVGLSLLGQMCAIYIPFFQSIFKTEKLGISDILLLLLISSSVFIVDELRKLWTRKKNEEDSTYFSNV------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : :: .: . . ...*. *:.* . **. *.. * : * **: : ::. :**::.:* : :*:**:.**::*::* ::*******:**.*****.*:********** *.****.*** :* *: . ** ***** * : :***:***:*::**:***:***.:***. * * : :. * .. . **:*****: *:.**:*:.** .:.** **:**: * ****** :** ** :**: ** :**:* *:* : *: *** ****************:*********:**.*:.:**::** *****. ************.*.**.: : *. .:. . :. : . : . : * :**:* : : ::*:**: **: : : : : * **.*::* **.* :: :: : *** * :: .*.* :* **: :. :. ****:.:*. : :* **:*: ****. *: :: *: .** : *:***:::**: * : : . :**:::* *. .:* :: :* :* *.:*.**::*:::*:: * :*.********. *** :***::**: ****.***:**:*.:*** **::********: **:**: ******:***:*::*:* :.:.*************:***************::*::: **: .: ::*:.:: .:* :: *: **:::* :*: :. * *******************:.* :***:* **: :*:** ** *::**: .:*:* :* :*:** * *:::*: ::*** :* *: * *. :. * ", "identical_positions": 390, "similar_positions": 271, "identity": "35.81%" }, { "cls_id": "homologset.agr.RGD:621312", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50503-1", "uniprot_id": "F10A1_RAT", "id": "P50503-1", "name": "Hsc70-interacting protein", "aln": "----MDPRKVSELRAFVKMCRQDPSVLHTEEMRFLREWVESMGGKVPPATHKAKSE---------ENTKEEKRDKT-TEDNIKTEEPSSEESDLEIDNEGVIEADTDAPQEMGDENAEITEAMMDEANEKKGAAIDALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAARDLALACKLDYDEDASAMLREVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHEKAQREEEARRQSGSQFGSFPGGFPGGMPGNFPGGMPGMGGAMP---GMAGMPGLNEILSDPEVLAAMQ-DPEVMVAFQDVAQNPSNMSKYQNNPKVMNLIS-----KLSAKFGGHS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99L47-1", "uniprot_id": "F10A1_MOUSE", "id": "Q99L47-1", "name": "Hsc70-interacting protein", "aln": "----MDPRKVSELRAFVKMCRQDPSVLHTEEMRFLREWVESMGGKVPPATHKAKSE---------ENTKEEKRDKT-TEENIKTEELSSEESDLEIDNEGVIEPDTDAPQEMGDENAEITEEMMDEANEKKGAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLREVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARRQSGSQYGSFPGGFPGGMPGNFPGGMPGMGGAMPGMAGMAGMPGLNEILSDPEVLAAMQ-DPEVMVAFQDVAQNPSNMSKYQSNPKVMNLIS-----KLSAKFGGQS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50502-1", "uniprot_id": "F10A1_HUMAN", "id": "P50502-1", "name": "Hsc70-interacting protein", "aln": "----MDPRKVNELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSE---------ENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARRQSGAQYGSFPGGFPGGMPGNFPGGMPGMGGGMP---GMAGMPGLNEILSDPEVLAAMQ-DPEVMVAFQDVAQNPANMSKYQSNPKVMNLIS-----KLSAKFGGQA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NFI4-1", "uniprot_id": "F10A5_HUMAN", "id": "Q8NFI4-1", "name": "Putative protein FAM10A5", "aln": "----MDPCKVNELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSE---------ENTKEEKPDSKKVEEDLKADEPSTEESDLEIDKEGVIEPDTDAPQEMGDENVEITEEMMDQANDKKVAAIEVLNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIQDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLAFACKLDYDEDASAMLKEVQPRAQKIAEHWRKYERKHEEREIKERIERVKKAQEEQERAQREEEARRQSGAHYGPFPGGFPGGMPGNFPGGMPGMGGDMP---GMAGMPGLNEILSDPEALAAMQ-DPEVMVAFQDVAQNPANMSKYQSNPKVMNLIS-----KLSAKFGGQA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IZP2-1", "uniprot_id": "ST134_HUMAN", "id": "Q8IZP2-1", "name": "Putative protein FAM10A4", "aln": "----MDPRKVNELRAFVKMCKKDPSILHTQEMRFLREWVESMGG---TATQKAKSE---------ENTKEEKPDSK-VEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEVMDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKRRGKAHRLLGHWEEAAHDLALACKFDYDEDASAMLKEVQPRAQKIAEHQRKYERKREE----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86DS1-1", "uniprot_id": "F10A2_DROME", "id": "Q86DS1-1", "name": "Hsc70-interacting protein 2", "aln": "MAFTMQTGDLKKLKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVPPGQFNGGSAGGKCPFGGVAGAKANEPANA-PEDSEDEKSLSDPESDVELDMEGVIEADSDPAQPMGNYSKKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLRQACKLDFDEETDEWLKEVTPNAKKIEQHRLKQERRQAERKIKERQRDQRRARKEQEKHN------ASSGGSSGEFSGGNPG------NGNMSDILGAMS---DPEVSAAIQDILSNPGNITKYASNPKIYNLIKKIVPGGDVGAAFGQAGEKAGKPSEPKPKKDSADFVDDGLD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "C4NYP8-1", "uniprot_id": "F10A1_DROME", "id": "C4NYP8-1", "name": "Hsc70-interacting protein 1", "aln": "MAFTMQTGDLKKLKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVPPGQFNGGSAGGKCPFGGVAGAKANEPANA-PEDSEDEKSLSDPESDVELDMEGVIEADSDPAQPMGNYSKKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLRQACKLDFDEETDEWLKEVTPNAKKIEQHRLKQERRQAERKIKERQRDQRRARKEQEKHN------ASSGGSSGEFSGGNPG------NGNMSDILGAMS---DPEVSAAIQDILSNPGNITKYASNPKIYNLIKKIVPGGDVGAAFGQAGEKAGKPSEPKPKKDSADFVDDGLD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. .:.:*: *:.:. ::*:.*: :::*::::**.:** .. :. * .:* :: . *:. . .. * ***:*:* *****.*:*..* **: . : ** :::*.: : * .. .: ::::** *:*.**:*.* *:::***...*:**:****.*:*** *:*:*.* * ** **:*:****.:* **:** ***:*:**::. *:** *.*:** :* * **:: * ", "identical_positions": 93, "similar_positions": 95, "identity": "23.66%" }, { "cls_id": "homologset.agr.RGD:621313", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZC5-1", "uniprot_id": "D3ZZC5_RAT", "id": "D3ZZC5-1", "name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "aln": "--------MAADQNGHEEWVGSAYLFLESSMDKVVLSEAYTDPKKKVAIYKALQAALSESGDSPDVLQILKIHCSDPQLIVQLRFCGRLLCGRFLQAYREGALRTALQRCMAAALAQ-EAVRLQLELRAGAEQLDSWLTDEERCLNYILAQKPDRLRDEELAELEDEFCKLTCDSTGQGGATQVAPAGSKSLVSSPAEEKP--LPAAGQTFLFHGQLIVNRPLNLQDQQTFARSVGLKWRRVGRSLQRSCRALRDPALDSLAYEYERDGLYEQAFQLLRRFIQAEGRRATLQRLVEALEENELTSLAEDLLGQAEPEGGQA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U0V2-1", "uniprot_id": "TRADD_MOUSE", "id": "Q3U0V2-1", "name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "aln": "--------MAAGQNGHEEWVGSAYLFLESAVDKVILSEAYTDPKKKVAIYKALQTALSESGDSSDVLQILKIHCSDPQLIVQLRFCGRVLCGRFLQAYREGALRTALQRCMAPALAQ-EALRLQLELRAGAEQLDSWLTDEERCLNYILAQKPDRLRDEELAELEDELCKLTCDCTGQGGAIQVASAGSKFPVSSPTEEKP--LPAACQTFLFHGQLVVNRPLTLQDQQTFARSVGLKWRRVGRSLQRNCRALRDPALDSLAYEYERDGLYEQAFQLLRRFMQAEGRRATLQRLVEALEENELTSLAEDLLGQAEPDGGLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15628-1", "uniprot_id": "TRADD_HUMAN", "id": "Q15628-1", "name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "aln": "--------MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQMLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQ-HSVPLQLELRAGAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9I9N5-1", "uniprot_id": "TRADD_DANRE", "id": "Q9I9N5-1", "name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "aln": "MDSIDTKRLNDSNASDRALSGCAVLFLGCSSLEHNFLSLYKDERGKFSVFKVIKLTLSDSVGGLEGYEILKLHDADPYLGVELKFMAMPPCQRFLESYACGSLTQFLSQHASRLLALPDGVEIETQLKAGVHTLDHSLQDIEICLDHIRQSQPVRLRDDEVTQLEQQLQN------------------SYGPPSQPPQELP------RNCFLFQKRVFDDRPLTPADQQRFAAHVGRDWKRVGRALQKNCRALKGPAIDNLAYEYEREGLYEQAYQLLGRFIQSEGRSAKLSRLISALEETKMTSMAEIMLGIQPRD----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: ... *.* **: .: : : . * . : *.::::.:: :*::* .. : ::**:* :** * *:*:* . * ***.:* *:* *.: : ** ..: :: :*:**.. ** * * * **. * .:* ****:*:::**: : : .. .: * : ***: : . :***. *** ** ** .*::***:**:.****:.**:*.*******:******:*** **:*:*** *.*.**:.****.::**:** :** : ", "identical_positions": 109, "similar_positions": 95, "identity": "33.96%" }, { "cls_id": "homologset.agr.RGD:621314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O02649-1", "uniprot_id": "CH60A_DROME", "id": "O02649-1", "name": "Heat shock protein 60A", "aln": "---MFRLPVSLARSS-ISRQLA---MRGYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKG-ANPVEIRRGVMLAVETVKDNLKTMSRPVSTPEEIAQVATISANGDQAIGNLISEAMKKVGRDGVITVKDGKTLTDELEVIEGMKFDRGYISPYFINSSKGAKVEFQDALLLLSEKKISSVQSIIPALELANAQRKPLVIIAEDIDGEALSTLVVNRLKIGLQVAAVKAPGFGDNRKSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGEVVITKDDTLLLKGK-GKKDDVLRRANQIKDQIEDTTS-EYEKEKLQERLARLASGVALLRVGGSSEVEVNEKKDRVHDALNATRAAVEEGIVPGGGTALLRCIEKLEGVE-TTNEDQKLGVEIVRRALRMPCMTIAKNAGVDGAMVVAKVENQAGD---YGYDALKGEYGNLIEKGIIDPTKVVRTAITDASGVASLLTTAEAVVTEIPKEDGAPA------------------------MPGMGGM---GGMGGMGGMGGMM-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMN5-1", "uniprot_id": "CH60C_DROME", "id": "Q9VMN5-1", "name": "60 kDa heat shock protein homolog 2, mitochondrial", "aln": "MMRMFRYTNTLQRTAKISHVLW---ARNYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIALKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISRG-ASPVEIRRGVMLAIETVKDNLRRLSRPVNTPEEICQVATISANGDKSVGNLISEAIKKVGRDGVITVKDGKTLCDELEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEKKIKSAPSIVPALELANAQRKPLVIIAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNRKENLMDMAVATGGIVFGDEANMVRLEDIKMSDFGRVGEVVVSKDDTMLLKGK-GQKAEVEKRVEGLREAIKESTS-SYEKEKMQERLARLSSGVALLRVGGSSDVEVSEKKDRVIDALNATRAAVEEGIVPGGGTALLRCIQKLNDLK-GANEDQNMGIEIIRRALRMPCLTIAKNAGVDGAMVVAKVEILDGD---YGYDALKGEYGNMIERGIIDPTKVVRTAISDAAGVASLLTTAEAVVTELPLEEAAAAG----------------------AAAGLGAL---GGMG-MGGMG-M--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P63038-1", "uniprot_id": "CH60_MOUSE", "id": "P63038-1", "name": "60 kDa heat shock protein, mitochondrial", "aln": "---MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKG-ANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGK-GDKAHIEKRIQEITEQLDITTS-EYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLK-PANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSE---VGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEE---------------------------KDPGMGAM---GGMG--GGMGGGMF------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63039-1", "uniprot_id": "CH60_RAT", "id": "P63039-1", "name": "60 kDa heat shock protein, mitochondrial", "aln": "---MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKG-ANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGK-GDKAHIEKRIQEITEQLDITTS-EYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLK-PANEDQKIGIEIIKRALKIPAMTIAKNAGVEGSLIVEKILQSSSE---VGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEAVVTEIPKEE---------------------------KDPGMGAM---GGMG--GGMGGGMF------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10809-1", "uniprot_id": "CH60_HUMAN", "id": "P10809-1", "name": "60 kDa heat shock protein, mitochondrial", "aln": "---MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKG-ANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGK-GDKAQIEKRIQEIIEQLDVTTS-EYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLT-PANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSE---VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEE---------------------------KDPGMGAM---GGMG--GGMGGGMF------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P19882-1", "uniprot_id": "HSP60_YEAST", "id": "P19882-1", "name": "Heat shock protein 60, mitochondrial", "aln": "---MLRSSVVRSRATLRPLLRR---AYSSHKELKFGVEGRASLLKGVETLAEAVAATLGPKGRNVLIEQPFGPPKITKDGVTVAKSIVLKDKFENMGAKLLQEVASKTNEAAGDGTTSATVLGRAIFTESVKNVAAG-CNPMDLRRGSQVAVEKVIEFLSANKKEITTSEEIAQVATISANGDSHVGKLLASAMEKVGKEGVITIREGRTLEDELEVTEGMRFDRGFISPYFITDPKSSKVEFEKPLLLLSEKKISSIQDILPALEISNQSRRPLLIIAEDVDGEALAACILNKLRGQVKVCAVKAPGFGDNRKNTIGDIAVLTGGTVFTEELD-LKPEQCTIENLGSCDSITVTKEDTVILNGS-GPKEAIQERIEQIKGSIDITTTNSYEKEKLQERLAKLSGGVAVIRVGGASEVEVGEKKDRYDDALNATRAAVEEGILPGGGTALVKASRVLDEVV-VDNFDQKLGVDIIRKAITRPAKQIIENAGEEGSVIIGKLIDEYGDDFAKGYDASKSEYTDMLATGIIDPFKVVRSGLVDASGVASLLATTEVAIVDAPEPP---------------------------AAAGAGGMP--GGMP---GMPGMM-------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VPS5-1", "uniprot_id": "CH60B_DROME", "id": "Q9VPS5-1", "name": "60 kDa heat shock protein homolog 1, mitochondrial", "aln": "---MFRSCVPKAITSSRCFARM------YSKDVRFGSGVRAMMIRGVDILADAVAVTMGPKGRSVIVERPWTSPKITKDGFTVARSIALKDQHMNLGAKLVQDVADNTNESAGDGTTTATVLARAIAKEGFNQITMG-ANPVEIRRGVMLAVDVVKDKLKEMSKAVETREEIQQVATLSANGDTEIGRLIGEATDKVGPRGTITVKDGKRLKDELNIIQGLRFDNGYVSPFFVNSSKGSKVEFANALVMISLKKITGLSQIVKGLEQSLRQRRPLIIIAEDISGEALNALVLNKLRLGLQVCAVKSPSYGHHRKELIGDISAATGATIFGDDINYSKMEEAKLEDLGQVGEAVISKDSTMLLQGK-PKTGLLEMRIQQIQDELAEKQIKPEQRDRLRQRLSALTKGVAVLHIGGGSEVEVNEKKDRVVDALNATRAAIEEGIVPGGGTAFLRCIPYLQELK-TESADLQKGVDIVCNALRMPCQTIAQNAGVDGPMVVAKVLNGSED---YGYDAMGDEYCRLVEKGIIDPTKVLRTAITDAAGVASLLSTTEVVITDSRNDDLLSKLSGAGGGMDDGLDMNMGGLEELAALSGLGGMGGMGGMGGMGGMGGMGGGFGGMGAGGGMSASASNDGPTAEEMNEMVKAIPGMEQVEVRDIDSGMM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJX7-1", "uniprot_id": "Q9VJX7_DROME", "id": "Q9VJX7-1", "name": "", "aln": "---MLSRLGRSGRAG----------VRTFANDIRFGAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISPRITKDGITVANNVQLGNRRQDMGVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLLREGILEGSRAVCDALGEMSQSVDTIGQVEAVAKVALNGDERLAELIGDIILELGDSGVILLKESHSPFDEAKIQEGITIASGYYSPFFAKQS--HTLELENCLLLLTLAKIDQVEQILPALELARLKERPLLIIAKNFGSDLLKILVLNNLQGRVQVCAVKAPSFGDEQCEEMEDIAFATGGHLLEDASS---LADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQDIRELIDEAFT-DVELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAVRVAISDGVVPGGGTAYLRCIPVLDELPPTDIMELQVGREIVKDALRLPCYTIARNAGVDPNEVLRRVLKGSGN---YGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLATTEVLITKQPTKP---------------------------KIPKNQVT---KDLAKLVGM-----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ::::** *. :::**: **:***.*:*****.*::*: .*::****.***..: * :: ::*.:*:::.:.:**: .*****:**:*.*.* :... : . . :*.* . * * .: : * :: **.:: *** :..::.. ::* *.* :::.: ** :: :*: : *: **:* . . . *: . ::: ** .*: .** : .:**:***::. .: * ::*.*: ::* ***:*.:*..: . : *:: :*. :: : : ::* . : ..: :*: : * : : : : :::. **. * :* : :** *::**.*:*** ***:*.*.*:.:*:: *** * ::. *: : : : * :*: :: *. * .*** : :: :: : **** .:: :: **:** **:::.: .*:*:****:*:*. :.. . .: ** ", "identical_positions": 139, "similar_positions": 201, "identity": "20.97%" }, { "cls_id": "homologset.agr.RGD:621315", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQV6-1", "uniprot_id": "MLP3B_MOUSE", "id": "Q9CQV6-1", "name": "Microtubule-associated protein 1 light chain 3 beta", "aln": "MPSEKTFKQRRSFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESERDEDGFLYMVYASQETFGTAMAV-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62625-1", "uniprot_id": "MLP3B_RAT", "id": "Q62625-1", "name": "Microtubule-associated protein 1 light chain 3 beta", "aln": "MPSEKTFKQRRSFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESERDEDGFLYMVYASQETFGTALAVTYMSALKATATGREPCL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9GZQ8-1", "uniprot_id": "MLP3B_HUMAN", "id": "Q9GZQ8-1", "name": "Microtubule-associated protein 1 light chain 3 beta", "aln": "MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFGMKLSV-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NCE7-1", "uniprot_id": "MP3B2_HUMAN", "id": "A6NCE7-1", "name": "Microtubule-associated protein 1 light chain 3 beta 2", "aln": "MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVCASQETFGMKLSV-----------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********:******************************************************************************************:********* ******* ::* ", "identical_positions": 118, "similar_positions": 4, "identity": "83.1%" }, { "cls_id": "homologset.agr.RGD:621316", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P33434-1", "uniprot_id": "MMP2_MOUSE", "id": "P33434-1", "name": "72 kDa type IV collagenase", "aln": "MEARVAWGALAGPLRVLCVLCCLLGRAIAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARALKVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQGTSYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRNDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSHDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADSWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33436-1", "uniprot_id": "MMP2_RAT", "id": "P33436-1", "name": "72 kDa type IV collagenase", "aln": "MEARLVWGVLVGPLRVLCVLCCLLGHAIAAPSPIIKFPGDVSPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARALKVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNGDGQPCKFPFRFQGTSYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSNDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFSGDKFWRYNEVKKKMDPGFPKLIADSWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08253-1", "uniprot_id": "MMP2_HUMAN", "id": "P08253-1", "name": "72 kDa type IV collagenase", "aln": "MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASP--DIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :. *.*.****.**:* ***.:* *************:*********************************************************************************************************::********************************************************************************************:**.****************************************.:***************:*****************************************************************.***:*****:*******************************************************:***********.** * * ************************************************** *************************************:************************:****************:************************:***************************************************", "identical_positions": 628, "similar_positions": 25, "identity": "94.86%" }, { "cls_id": "homologset.agr.RGD:621317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28862-1", "uniprot_id": "MMP3_MOUSE", "id": "P28862-1", "name": "Stromelysin-1", "aln": "MKGLPVLLWLCVVVCSSYPLHDSARDDDAGMELLQKYLENYYGLAKDVKQFIKKKDSSLIVKKIQEMQKFLGLEMTGKLDSNTMELMHKPRCGVPDVGGFSTFPGSPKWRKSHITYRIVNYTPDLPRQSVDSAIEKALKVWEEVTPLTFSRISEGEADIMISFAVGEHGDFVPFDGPGTVLAHAYAPGPGINGDAHFDDDERWTEDVTGTNLFLVAAHELGHSLGLYHSAKAEALMYPVYKSSTDLSRFHLSQDDVDGIQSLYGTPTASPDVLVVPTKSNSLEPETSPMCSSTLFFDAVSTLRGEVLFFKDRHFWRKSLRTPEPEFYLISSFWPSLPSNMDAAYEVTNRDTVFIFKGNQFWAIRGHEELAGYPKSIHTLGLPATVKKIDAAISNKEKRKTYFFVEDKYWRFDEKKQSMEPGFPRKIAEDFPGVDSRVDAVFEAFGFLYFFSGSSQLEFDPNAKKVTHILKSNSWFNC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P03957-1", "uniprot_id": "MMP3_RAT", "id": "P03957-1", "name": "Stromelysin-1", "aln": "MKGLPVLLWLCTAVCSSYPLHGSE--EDAGMEVLQKYLENYYGLEKDVKQFTKKKDSSPVVKKIQEMQKFLGLKMTGKLDSNTMELMHKPRCGVPDVGGFSTFPGSPKWRKNHISYRIVNYTLDLPRESVDSAIERALKVWEEVTPLTFSRISEGEADIMISFAVEEHGDFIPFDGPGMVLAHAYAPGPGTNGDAHFDDDERWTDDVTGTNLFLVAAHELGHSLGLFHSANAEALMYPVYKSSTDLARFHLSQDDVDGIQSLYGPPTESPDVLVVPTKSNSLDPETLPMCSSALSFDAVSTLRGEVLFFKDRHFWRKSLRTPEPGFYLISSFWPSLPSNMDAAYEVTNRDTVFILKGNQIWAIRGHEELAGYPKSIHTLGLPETVQKIDAAISLKDQKKTYFFVEDKFWRFDEKKQSMDPEFPRKIAENFPGIGTKVDAVFEAFGFLYFFSGSSQLEFDPNAGKVTHILKSNSWFNC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P08254-1", "uniprot_id": "MMP3_HUMAN", "id": "P08254-1", "name": "Stromelysin-1", "aln": "MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVSTLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.**:** **..***:***..: :*:.*:::********.* ****** ::***. :****:********::******:*:*:*:********** * **** *****.*::******* ***:::****:*:***************: ************ ***** ****** *********** **********:**.*.************:******:***::******:*:* ***:**:*****::*******.*. **:. :***:. . :* * . *..:* **********:*:************. ** ::***********.:*******.:* ***:****:*****:* ****:.*****:* **:******* *::.*********:******::**:* **::***:***:.:::***** ***:***:*********** **** ******:**", "identical_positions": 346, "similar_positions": 95, "identity": "72.54%" }, { "cls_id": "homologset.agr.RGD:621318", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CHZ9-1", "uniprot_id": "MTF1A_MOUSE", "id": "Q8CHZ9-1", "name": "Transcription termination factor 1a, mitochondrial", "aln": "--------------------MASRNIWCVRRNFLFDLRDWMLQYSAEVFLKSISFRPFSAECDSKDKESLEEEREDLLSNLVTMGVDIDMARRRQPGVFNKAVTN---EQELKLFLLSKGASDKVIGSIISRYPRAITRTPESLSKRWDLWRKIMASDLEIVNILERSPESFFRSNNNLNLENNIKFLCSVGLTHKCLCRLLTNAPRTFSNSLNLNKQMVEF-LQETGMSLGHNDPRDFVRKIISKNPSILIQSTKRVKTNIEFLQSTFNLNKRDLLLLICGPGAR---ILDLSNDCTKKNYTNIRERLLS-LGCSEEEVQRFVLSYLNMVFLSEKKFNDKIDCLIEEK-ISASQIIENPRILDSSINTLKTRIRELSHAGYDLSTSSIALLSWSQRRYEAKLKRLCG-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B9EJ57-1", "uniprot_id": "MTF1B_MOUSE", "id": "B9EJ57-1", "name": "Transcription termination factor 1b, mitochondrial", "aln": "--------------------MASRNIWCVRRNFLFDLRGWMLQYSAEVFLKSISFRTFSVECDSKDKESLEEEREDLLSNLVTMGVDIDMARRRQPGVFNKAVTN---EQELKIFLLSKGASDKVIGSIISRYPRAITRTPESLSKRWDLWRKIMASDLEIVNILERSPESFFRSNNNLNLENNIKFLCSVGLTHKCLCRLLTNAPRTFSNSLNLNKQMVEF-LQETGMSLGHNDPRDFVRKIISKNPSILIQSTKRVKTNIEFLQSTFNLNKQDLLLLICGPGAR---ILDLSNDCTKKNYTNIRERLLS-LGCSEEEVQRFVLSYLNMVFLSEKKFNDKIDCLIEEK-ISASQIIENPRILDSSINTLKTRIRELSHAGYDLSTSSIALLSWSQRRYEAKLKRLCG-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9EPI8-1", "uniprot_id": "MTEF1_RAT", "id": "Q9EPI8-1", "name": "Transcription termination factor 1, mitochondrial", "aln": "--------------------MASRNIWRVRRNFLFDLRGWVPQYSAEVFLKSIPFRPFSVECNSKD-----GENGDLLNNLLTMGVDVDMARRRQPGVFNKAVTN---EQELKMFLLSKGASDKVIGSIISRYPRAITRTPESLSKRWDLWREIMASDLEIVNILERSPESFFRSNNNLNLENNIKFLCSVGLTHKCLCRLLTSAPRTFSNSLNLNKQMVEF-LQETGISLGHNNPTDFVRKIISKNPSILIQSTKRVKTNIEFLQSTFNLDKEDLLLLICGPGAR---ILDLSNDCTKRNYTNIKKRLLS-LGCTEEEVQKFVLSYLNMIFLSEKKFNDKIDCLLEEK-ISTSQILENPRVLDSSIHTLKTRIRELAHAGYDVSTSSIALLSWSQRRYEAKLKRLSG-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99551-1", "uniprot_id": "MTEF1_HUMAN", "id": "Q99551-1", "name": "Transcription termination factor 1, mitochondrial", "aln": "MQSLSLGQTSISKGLNYLTIMAPGNLWHMRNNFLFGSRCWMTRFSAENIFKSVSFRLFGVKCHNTDSEP--LKNEDLLKNLLTMGVDIDMARKRQPGVFHRMITN---EQDLKMFLLSKGASKEVIASIISRYPRAITRTPENLSKRWDLWRKIVTSDLEIVNILERSPESFFRSNNNLNLENNIKFLYSVGLTRKCLCRLLTNAPRTFSNSLDLNKQMVEF-LQAAGLSLGHNDPADFVRKIIFKNPFILIQSTKRVKANIEFLRSTFNLNSEELLVLICGPGAE---ILDLSNDYARRSYANIKEKLFS-LGCTEEEVQKFVLSYPDVIFLAEKKFNDKIDCLMEEN-ISISQIIENPRVLDSSISTLKSRIKELVNAGCNLSTLNITLLSWSKKRYEAKLKKLSRFA---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3F3-1", "uniprot_id": "MTTF_DROME", "id": "Q9V3F3-1", "name": "Transcription termination factor, mitochondrial", "aln": "-----MIRSLLRSFETALKLHAGLNMHPMHCSRRLLFSQYENRASPSRLTSSGTLGSNEAENDYVPYRQDRETGTKTRVLLEALRERFRFTDAELQKIISDELVHRCYRGRSLTLVMDTLQLEGVSRRSFVEYPWLLSLDNKRLELKMQLLKSMDFKDINHFVPFLRLTVPRLR--KLVGALNSERDAMPQRNRVYYISEKLDVSPDIVSKYLSKRLFILEMPFEMFEKNLQHMIDYNVSPINVLKDLWAFRYTPKSVQLRLERAKRAKKDKIMPWMVRCPEPILQRSLKLSLDELKVLGEFSSVVEYLAHRLGFSTSEAKAIMDKHPQVHTVRVTKIKEVLDYLLDEAQFTRFEVAQNPRILCHSLKTTKERMEELKSHGCRPS--SLVILCRSRREYDKFLQNWISHERNPQSVSEG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: :: . : : : *.. : .* .: .: . . * :: . :: . :: :.: . :::.. . * : .** :: : *. : :* :.: .*:: . : * . . :* : :. *. : . :.. * :* .*: *. . ::*: :: .* * :. : *: : :.* *: .:* : : : . :: * . *.*.: . .::.: : * ** : .*.: :: .: :: : .*::: :* *::* :: :: :***:* *: * * *:.** * * .:.:*. *::.*: *:. ", "identical_positions": 52, "similar_positions": 139, "identity": "12.41%" }, { "cls_id": "homologset.agr.RGD:621319", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6U0-1", "uniprot_id": "FGR_RAT", "id": "Q6P6U0-1", "name": "Tyrosine-protein kinase Fgr", "aln": "MG-CVFCKKLEPAP--KEDVGLEGDFRSQGAE-ERYYPDPTQGRSSS----------ISPQPISP--AFLNVGNIRSVSGTGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQAEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDMGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCM-VMKPQTLGL---AKDAWEIDRNSIALDRRLGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVS-EEPIYIVTEFMCYGSLLDFLK--DRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLICKIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P14234-1", "uniprot_id": "FGR_MOUSE", "id": "P14234-1", "name": "Tyrosine-protein kinase Fgr", "aln": "MG-CVFCKKLEPAS--KEDVGLEGDFRSQTAE-ERYFPDPTQGRTSS----------VFPQPTSP--AFLNTGNMRSISGTGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGHRGYVPSNYVAPVDSIQAEEWYFGKISRKDAERQLLSSGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDTGGYYITTRAQFDSIQDLVRHYMEVNDGLCYLLTAPCT-TTKPQTLGL---AKDAWEIDRNSIALERRLGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVS-EEPIYIVTEFMCYGSLLDFLK--DREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09769-1", "uniprot_id": "FGR_HUMAN", "id": "P09769-1", "name": "Tyrosine-protein kinase Fgr", "aln": "MG-CVFCKKLEPVATAKEDAGLEGDFRSYGAA-DHYGPDPTKARPASSFAHIPNYSNFSSQAINP--GFLDSGTIRGVSGIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCT-IMKPQTLGL---AKDAWEISRSSITLERRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHDKLVQLYAVVS-EEPIYIVTEFMCHGSLLDFLK--NPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLEDYFTSAEPQYQPGDQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7B9-1", "uniprot_id": "A0AB13A7B9_DANRE", "id": "A0AB13A7B9-1", "name": "Tyrosine-protein kinase", "aln": "MG-CACCKQRKASKAVSNQNSCDAFNGTQASEPSRYIPDPTFNSGIPNFN-------DFSNPLTPPTSIINPARPPGLTGGGVTLFIALYEYDARTEDDLSFQKGEKFHIINNTEGDWWEARSLDTGKSGYIPSNYVAPVDSIQAEEWYFGKMGRKDAERQLLAQNNPRGTFLIRESETTKGAYSLSIRDWDDAKGDHVKHYKIRKLDNGGYYITTRTQFDTVQQLVEHYTERAAGLCCRLIGSCR-RGMPKLADLSVKTKDVWEIPRESLQLIKKLGNGQFGEVWMGMWNGTTKVAVKTLKPGTMSPEAFLDEAQIMKRLRHDKLVQLYAVVS-EEPIYIITEFMSQGSLLDFLK--DGDGRNLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDGLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVERGYRMPCPQGSPASLHELMLQCWRKDPDERHTFEYLQSFLEDYFTATEPQYQPGENL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9J3-1", "uniprot_id": "SRC42_DROME", "id": "Q9V9J3-1", "name": "Tyrosine-protein kinase Src42A", "aln": "MGNCLTTQKGEPDKP-ADRIKLDDPPTIGVGVGVPQIPMPSHAGQPP-------------EQIRP----VPQIPESETAGANAKIFVALYDYDARTDEDLSFRKGEHLEILNDTQGDWWLARSKKTRSEGYIPSNYVAKLKSIEAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRD-----GDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFYTSDQSDYKEAQAY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * :: :. : : . * *: . : * : :* ...:*:***:*:*** :**:* ***::.*:*:*: *** *** .: * :****** :.**:** *** *: * :**::** * :*:****:**: :. ****:** ** :***:**:** **::*: *. * ::*:**.** : *** * .* * .* ::* *** * *: : ::**.* **:** * ** :* **:****.***.*: ** ***:** *** **:***** : ******:**:* ****::*: .*:.* : *:*****:* ****:* ******* * *:***: *********** ::** . *::*********** :.:*::**************:* **:*****.: *** ***:**:** * .. *:* * : *: ** .* *** ** ***::*: :.:*: .: ", "identical_positions": 250, "similar_positions": 119, "identity": "46.3%" }, { "cls_id": "homologset.agr.RGD:621320", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P50282-1", "uniprot_id": "MMP9_RAT", "id": "P50282-1", "name": "Matrix metalloproteinase-9", "aln": "MSPWQPLLLVLLALGYSFAAPHQRQPTYVVFPRDLKTSNLTDTQLAEDYLYRYGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGELDSETLKAIRSPRCGVPDVGKFQTFDGDLKWHHHNITYWIQSYTEDLPRDVIDDSFARAFAVWSAVTPLTFTRVYGLEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGAVVPTYFGNANGAPCHFPFTFEGRSYLSCTTDGRNDGKPWCGTTADYDTDRKYGFCPSENLYTEHGNGDGKPCVFPFIFEGHSYSACTTKGRSDGYRWCATTANYDQDKADGFCPTRADVTVTGGNSAGEMCVFPFVFLGKQYSTCTSEGRSDGRLWCATTSNFDADKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYHYHEDSPLHEDDIKGIHHLYGRGSKPDPRPPATTAAEPQPTAPPTMCSTAPPMAYPTGGPTVAPTGAPSPGPTG----------------PPTAGPSEAPTESSTPDDNPCNVDVFDAIADIQGALHFFKDGRYWKFSNHGGNQLQGPFLIARTWPAFPSKLNSAFEDPQPKKIFFFLWAQMWVYTGQSVLGPRSLDKLGLGSEVTLVTGLLPRRGGKALLISRERIWKFDLKSQKVDPQSVTRLDNEFSGVPWNSHNVFQYQDKAYFCHDKYFWRVSFHNRVN-------QVDHVAYVTYDLLQCP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41245-1", "uniprot_id": "MMP9_MOUSE", "id": "P41245-1", "name": "Matrix metalloproteinase-9", "aln": "MSPWQPLLLALLAFGCSSAAPYQRQPTFVVFPKDLKTSNLTDTQLAEAYLYRYGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGELDSQTLKAIRTPRCGVPDVGRFQTFKG-LKWDHHNITYWIQNYSEDLPRDMIDDAFARAFAVWGEVAPLTFTRVYGPEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGAGVQGDAHFDDDELWSLGKGVVIPTYYGNSNGAPCHFPFTFEGRSYSACTTDGRNDGTPWCSTTADYDKDGKFGFCPSERLYTEHGNGEGKPCVFPFIFEGRSYSACTTKGRSDGYRWCATTANYDQDKLYGFCPTRVDATVVGGNSAGELCVFPFVFLGKQYSSCTSDGRRDGRLWCATTSNFDTDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPLYSYLEGFPLNKDDIDGIQYLYGRGSKPDPRPPATTTTEPQPTAPPTMCPTIPPTAYPTVGPTVGPTGAPSPGPTSSPSPGPTGAPSPGPTAPPTAGSSEASTESLSPADNPCNVDVFDAIAEIQGALHFFKDGWYWKFLNHRGSPLQGPFLTARTWPALPATLDSAFEDPQTKRVFFFSGRQMWVYTGKTVLGPRSLDKLGLGPEVTHVSGLLPRRLGKALLFSKGRVWRFDLKSQKVDPQSVIRVDKEFSGVPWNSHDIFQYQDKAYFCHGKFFWRVSFQNEVNKVDHEVNQVDDVGYVTYDLLQCP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14780-1", "uniprot_id": "MMP9_HUMAN", "id": "P14780-1", "name": "Matrix metalloproteinase-9", "aln": "MSLWQPLVLVLLVLGCCFAAPRQRQSTLVLFPGDLRT-NLTDRQLAEEYLYRYGYTRVAEMRGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTT--PQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPTG----------------PPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLGPRRLDKLGLGADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQYREKAYFCQDRFYWRVSSRSELN-------QVDQVGYVTYDILQCPED", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ****:*.**.:* . *** ***.* *:** **:* **** **** *********.*:* **.:** ****:********:****** ****:*:*******:*:****.* ***.*********.*:***** :***:******:*. *:********. :********************************.*:*****************.*:** :**::**.***** ****** :******.** ***.***:**.* ::******.***:.**.:**** *****:*:*******.****************:** ******.* ** *******:*****.****:**:***:** *************:****************************************:* : *. **::**:.**::*** .:*:****:**: ********:*.* ** .:*: **..***.**.***. *****.* *.* . :* *:.***::*****:* . *::**** **:* : *. ***** * .***:* .*:*.**: .*::*** *:***** :***** *******.:*: *:* * ** **:* *:*:**:*:* ***:*. .:*. *.*** ::*::***::*****:.:::**** :..:* ***.*.*****:**** ", "identical_positions": 491, "similar_positions": 143, "identity": "66.98%" }, { "cls_id": "homologset.agr.RGD:621321", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63357-1", "uniprot_id": "MYO1D_RAT", "id": "Q63357-1", "name": "Unconventional myosin-Id", "aln": "MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKVLNIYGRDTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIMISGESGAGKTEASKYIMQYIAAITNPSQRAEIERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLHSLHLQKSLSSYNYIRVGAQLKSSINDAAEFKVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFIVDGDTPLIENGKVVSVIAELLSTKADMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVKNYDTTVHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDGMFLEALNSKLGKHGHFSSRKTCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLVRVVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKNMRDYGKHVKWPTPPKVLRRFEEALQSIFNRWRASQLIKTIPASDLPQVRAKVAAMEMLKGQRADLGLQRAWEGNYLASKPDTPQTSG---TFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTK-QYKVMK-TIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSK-QPTHESRIGELVGVLVNHFKSEK-RHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SYD0-1", "uniprot_id": "MYO1D_MOUSE", "id": "Q5SYD0-1", "name": "Unconventional myosin-Id", "aln": "MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKVLNIYGRDTVEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIMISGESGAGKTEASKYIMQYIAAITNPSQRAEIERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLHSLHLQKSLSSYNYIRVGAQLKSSINDAAEFKVVADAMKVIGFKPEEIQTVYKILAVILHLGNLKFIVDGDTPLIENGKVVSVIAELLSTKADMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDGMFLEALNSKLGKHGHFSSRKTCASDKILEFDRDFRIRHYAGDVVYSAIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKSKIFIRTPRTLFTLEELRAQMLVRVVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKNMRDYGKHVKWPTPPKVLRRFEEALQSIFNRWRASQLIKTIPASDLPQVRAKVAAMEMLKGQRADLGLQRAWEGNYLASKPDTPQTSG---TFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTK-QYKVMK-TIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSK-QPTHESRIGELVGVLVNHFKSEK-RHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94832-1", "uniprot_id": "MYO1D_HUMAN", "id": "O94832-1", "name": "Unconventional myosin-Id", "aln": "MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSIIAELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSG---TFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTK-QYKVMK-TIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSK-QPTHESRIGELVGVLVNHFKSEK-RHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9L8-1", "uniprot_id": "MYO1D_DANRE", "id": "E7F9L8-1", "name": "Unconventional myosin-Id", "aln": "MAEHESLEFGKADFVLLDNVSLEEFMANLKLRFEKGRIYSYIGEVVVSVNPYRAMNIYGRDVIEQYKGRELYERPPHLFAIADAAYKAMKRRNKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIFQQEGERSFHSFYQLVKGAPDAQLRSLHIQRDPTAYNYIKVGGQLKSSINDSAEFKAVADAMKVIGFTTEEIQTVYKILATILHLGNLKFGTDGDVTLIENSKLVSVLGDLLSTKEENVEKAMLYRTVATGRDVIDKQHTHQEASYGRDALAKAIYERLFCWIVGRINDIIEVKNYDARVHGKNTVIGVLDIYGFEIFQNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIFAVLDEACMNVGKVTDEMFLQALNGKLAKHAHYTSRKLSPTDKNLEFERDFRIRHYAGDVTYSVVGFIDKNKDTLFQDFKRLLYNSSNPVLKAMWPEGKLSITEVTKRPLTAATLFKNSMISLVEKLASKEPYYVRCIKPNDVKSPLLFEHERCKHQVEYLGLLENVRVRRAGFANRQTYPRFLQRYKMISEFTWPNHDLSSDKEAVKRLLQGCGFEHDVAYGKTKVFIRTPRTIFSLEEQRAEMVKRIVLFLQKVWRGTLARMRYRRMRAALIIIRAYRRYKVKSYIREVIRRFKNVRDMKDHGKHVKWPTPPKVLRKFEEALRSIYNRWWAWTLIKPLSPEKTVQIRAKVATLECLKGQRADLGLQRAWEGNYLKK--DSPGTAS---SFTLVSSDLQRKDKFMRVLFSSNVRKINRFNKAEDRALLITDRHLYKMDPLK-QYKPMK-SIPLYNVTGVSISPGKDQLVVFHTKDNRDLIVCLQGM-VPAGDSRIGELVGTLLSHFKSEK-RKLQVNTVSPIHCSMNGRKCTVVVETKISQSQPDFTKSRSGYILSVPGN---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q23978-1", "uniprot_id": "MY31D_DROME", "id": "Q23978-1", "name": "Unconventional myosin ID", "aln": "MAMQR--EAGVQDFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFENAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNVLIQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFHSFYQLLRGANDNELRQYELQKETGKYHYLNQGS--MDILTEKSDYKGTCNAFKTLGFSTDEVQTIWRTIAAVLHLGNVEFQTIEDELVISNKQHLKSTAKLLQVTETELSTALTKRVIAAGGNVMQKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQAR-FNSVIGVLDIYGFEIFDSNSFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPHKGIIAIMDEACLSVGKVTDDTLLGAMDKNLSKHPHYTSRQLKPTDKELKHREDFRITHYAGDVIYNINGFIEKNKDTLYQDFKRLLHNSKDANLSEMWPEGAQDIKKTTKRPLTAGTLFQRSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPNFRAGSDRDGVRVLIEEKKFAQDVKYGHTKIFIRSPRTLFALEHQRNEMIPHIVTLLQKRVRGWIVRRNFKKMKAAITIVRAYKAYKLRSYVQELANRLRKAKQMRDYGKSIQWPQPPLAGRKVEAKLHRMFDFWRANMILHKYPRSEWPQLRLQIIAATALAGRRPYWGQARRWVGDYLANSQENSGYEAYNGSIKNIRNHPADGETFQQVLFSSFVKKFNHFNKQANRAFIVSDSTIHKLDGIKNKFKDMKRTIKIRELTSISVSPGRDQLIVFHSSKNKDLVFSLESEYTPLKEDRIGEVVGIVCKKYHDLTGTELRVNVTTNISCRLDGKARIITVEAASNVEVPNFRPKEGNIIFEVPAAYCV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :. * * ****:* **: :** **: **::* **::**** **:***: :**** :.:.:******:*..********:**:.:*:*.:****:************** **:****:**.. : *:*****:*::**.:**:*********************:**:*.**:** *.*********: ** ***.*******::*. : *:. .:*:. *:*:. *. . :.: :::: ..:*:*.:**..:*:**::: :*.:*****::* . * :*.* : :. ..**... :..*: *.:*:* ::::*:*. :*.**:**:*****:*** **: *** * .:. .: : *:*************:.********************:*************** *.:*:****:** ***** ****:*::*:**:.****** :* *:: :*.** *::**: .:** *:. .**** ****** *. ***:******:******::**.:. *. ***** .*.:.*******.***:.** ** .* .***:********* **. :*:.** .***.*******:*******. ** * :** ******::****. **::.*: *:: * .** **::*:***:***:*:**. * :*: ::* :*** ** :.* .::: :**: *:* *: **::**::*: .*:: .: *:*:** ::** ** . *:.* *: ::: * * ::: . .. *:* :: : * *:*. * * * *:** . :.. . :: : .. :.: .****. *:*.*:*.* :**::::* ::*:* * ::* ** :* : ::*.:*:* *:***:***:..*:**:..* . * :.****:** : .:::. . .*:**... : * :.*: : **: . *:* .... *:.**. ", "identical_positions": 490, "similar_positions": 321, "identity": "48.23%" } ]