[ { "cls_id": "homologset.agr.MGI:2443787", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A723-1", "uniprot_id": "RN152_RAT", "id": "D4A723-1", "name": "E3 ubiquitin-protein ligase RNF152", "aln": "METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGITKLPPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERTLLPGDMGCRLLPGSQQKSLTVVTIPAEQQPLQG-GAPQEAVEEEPDRRGVAKSSTWSGVCTVILVACVLVFLLGIVLHNMSCISKRFTVISCG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG47-1", "uniprot_id": "RN152_MOUSE", "id": "Q8BG47-1", "name": "E3 ubiquitin-protein ligase RNF152", "aln": "METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGITKLPPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERTLLPGDMGCRLLPGSQQKSLTVVTIPAEQQPLQG-GAPPEAVEEEPDRRGVVKSSTWSGVCTVILVACVLVFLLGIVLHNMSCISKRFTVISCG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N8N0-1", "uniprot_id": "RN152_HUMAN", "id": "Q8N8N0-1", "name": "E3 ubiquitin-protein ligase RNF152", "aln": "METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKLPPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCRLLPGSQQKSVTVVTIPAEQQPLQG-GAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLVFLLGIVLHNMSCISKRFTVISCG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58EC8-1", "uniprot_id": "RN152_DANRE", "id": "Q58EC8-1", "name": "E3 ubiquitin-protein ligase rnf152", "aln": "MDSLSQSSRLECQICFNYFSQRRLPKLLHCQHTCCSVCLSQMRLSQREIRCPWCRCVTQIPIGLSVSHLPDDPEVLSVISVSQSSEHTPIFIHLPNNGCYLLPVSLDTDGTPLPGQPTCHVGP----KSIGVFDVSDGQNHVLGHDGLGDGMEEEE--VVVVKTTAWTGVCTVLLVAFILIFLLGIVLHNMSCVSKRFTIISCG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::***.* *********:* ** ****.*:********.*** **:::****** :*::* *:***:********:**::.::*****:**:**.****:**:.:..: : ***: *:: * **: *. :. *: : * .. :.:*** *.*:::*:*****:*** :*:************:*****:****", "identical_positions": 118, "similar_positions": 56, "identity": "57.84%" }, { "cls_id": "homologset.agr.MGI:2443788", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE03-1", "uniprot_id": "D4AE03_RAT", "id": "D4AE03-1", "name": "Cytosolic endo-beta-N-acetylglucosaminidase", "aln": "-----MLPVPARCDTVHCS-------------------------------RINKDQEEEAVFRDVVNFAPDPLPARYYDKDTT-------RPISFYLSTLEELLAWTPLMEDGFNVALEP----------------LECRQPPLSSPRPRTLLCHDMMGGYLEDRFIQGSEVQNPYSFYHWQYIDIFVYFSHHTVTIPPVCWTNAAHRHGVCVLGTFITEWQEGGKLCEAFLAGDERSFQAVADRLVQIAQFFRFDGWLINIENSLSPAAVRNTPLFLQYLTRQLHQQVPGGLVLWYDSVVQSGQLKWQDELNEQNRVFFDSCDGFFTNYNWREDHLKRMVAQAGE---RLADVYVGIDVFARSNVVGGRFDTDKSLELIRKHGFSAALFAPGWVYECLE---------------KNDFFQNQDKFWRLLERFLPTHSICS-LPFVTSFCLGLGTRRVCYGK--EQAVGPWYHPSAQETQPLFGEHKLAGGNRGWVKTHCCLVDAWHGGSSLLLRGLIPPEVDSVAVRLFSMHVPVPP-KVFLSMVYKFEGSTDVQVALELTTGDASSCHVGGVLVLN-ETGTRYSPRPLRVPPTRLARWASSCGQQLSGGWIQRCYEVNLRGCLLQDLLVSFSRPPGSREEESFICRLGEIQVVDANSLLAPLPRVQNVTISQLRWLPLISGSEGLPTRLLLSCTLHWSYLLPRARCFRIHCWERTGSSSATEESPGTEKPEFLGLAFANQYRVVDLAVEAARFGQDGRVEFLVEPVPREGFLVPQAEWGRAVLLYSAPQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BX80-1", "uniprot_id": "ENASE_MOUSE", "id": "Q8BX80-1", "name": "Cytosolic endo-beta-N-acetylglucosaminidase", "aln": "---METSSVLTRGAARQRSPAAPE--------KQARDQTERRPGRRRQGRRINEDQEEEAVFREVVSFTPDPLPARYYDKDTT-------RPISFYLSTLEELLAWTPLMEDGFNVALEP----------------LVCRRPPLSSPRPRTLLCHDMMGGYLEDRFIQGSEVQNPYSFYHWQYIDIFVYFSHHTVTIPPVCWTNAAHRHGVCVLGTFITEWQEGGRLCEAFLAGDEPSFQAVADRLVQIAQFFRFDGWLINIENSLTPAAVRNTPLFLQYLTAQLHQQVPGGLVLWYDSVVQSGQLKWQDELNDQNRVFFDSCDGFFTNYNWREDHLQRMVAQAGE---RLADVYVGVDVFARSNVVGGRFDTDKSLELIRKHGFSAALFAPGWVYECLE---------------KSDFFQNQDKFWSLLERFLPTHSICS-LPFVTSFCLGLGTRRVCYGK--EQAVGPWYHPSAQETQPLFGEHKLAGDSRGWVKTHCCLTDAWHGGSSLLLRGLIPPEVDSVAVRLFSLHIPVPP-KVFLSMVYKFEGSTDVQVALELTTGDASSCHVGGMLVLN-ETGSRHSPRPLRVPPTRLARWASSCGQQLSGGWIQRCYEVNLRGCLLQDLLVSFSRPPGSREEESFICRLGEIQVVDASSLLAPLPRVQNVTISQIRWLPLITGSEGLPTRLLLSCTLHWSYLLLRARCFRIHCWKRTGSSSSVAESPETEKPTFLGLAFANQYRVVDLAVEAAGFGQDGRVEFLVEPVPREGFLVPQAEWGKAVLLFSVPQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFI3-1", "uniprot_id": "ENASE_HUMAN", "id": "Q8NFI3-1", "name": "Cytosolic endo-beta-N-acetylglucosaminidase", "aln": "---MEAAAVTVTRSATRRRRRQLQGLAAPEAGTQEEQEDQEPRPRRRRPGRSIKDEEEETVFREVVSFSPDPLPVRYYDKDTT-------KPISFYLSSLEELLAWKPRLEDGFNVALEP----------------LACRQPPLSSQRPRTLLCHDMMGGYLDDRFIQGSVVQTPYAFYHWQCIDVFVYFSHHTVTIPPVGWTNTAHRHGVCVLGTFITEWNEGGRLCEAFLAGDERSYQAVADRLVQITQFFRFDGWLINIENSLSLAAVGNMPPFLRYLTTQLHRQVPGGLVLWYDSVVQSGQLKWQDELNQHNRVFFDSCDGFFTNYNWREEHLERMLGQAGE---RRADVYVGVDVFARGNVVGGRFDTDKSLELIRKHGFSVALFAPGWVYECLE---------------KKDFFQNQDKFWGRLERYLPTHSICS-LPFVTSFCLGMGARRVCYGQ--EEAVGPWYHLSAQEIQPLFGEHRLGGDGRGWVRTHCCLEDAWHGGSSLLVRGVIPPEVGNVAVRLFSLQAPVPP-KIYLSMVYKLEGPTDVTVALELTTGDAGSCHIGGISVLNAETSSRHSLRPLRVPPTKLARWVGRCGRQLSGGWVQHCYEVSLRGCLLLDLLVCFSRPPGSREEESFTCRLGEIQVVDAASLLAPLPQVQAVTISHIRWQPSASEREGPPALLQLSCTLHWSFLLSQVRCFRIHCWGGMSDDSPGRELPRPEMPMFLGLAFATQYRIVDLLVEAAGPGQDRRMEFLVEPVPKEGFRVPQAEWGRAVLLYSAPA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1L251-1", "uniprot_id": "ENASE_DANRE", "id": "A1L251-1", "name": "Cytosolic endo-beta-N-acetylglucosaminidase", "aln": "---MIARKRKSNGSETTSGKIPKD----------------------DVSSESCLDQPADESVHEVVTFEPSTLPSVHYDPDTT-------EPISCSLKSLDELLSWKRNEASIFNVSSVP----------------LASRYPPLESCPRRTLVSHDMMGGYLEDRFIQGAEVETPYAFYHWEYIDIFNYFSHQMVTIPPAVWTNAAHRHGVLSIGTFITEWTDGAKTCEAFLADEE-SYRAAADKLVQISHCNGFDGWLINIENELSETAVNNTGPFLRYLTDQMHERVPGSVVIWYDSVLKDGKLLWQNELNDNNRMFFDACDGFFTNYNWTEQSLEGMKSYAAAQ-GRFADIYVGVDVFARGKVIGGKYETNKALELIRKYDLSTAIFAPDWVYECHE---------------KADFRQNQDKFWSLLSDFLYIHRPSSNLPFVSSFCQGFGKSLYWRGK--VETERSWFNLHAQEIQPLYLSESFGNG--GWLRTRGCSEDAWIGGSSLMLEGMIPSGLSDVCARIFSLHVPLAA-RTFVSFVFKPP--VGVKVSLELKTIDGPLCTFDGTEEIA---SRSVFPEALAESNQLVEQFAQNCGQWASDGWATRCFLLKMIGCSLREVCIRVSRD-GGDEDINFNCRIGEIMLLDADNLQAPLQSVEGICVNDVVWQTGVLKGDGHTLKVLLNATLRWQYPTRQVRHFRIHWRHLRGPDPRIPSGP----LTLIGRSYSALYRVVELEVPAAP----GLIELVVEPVSKEGFSVPEAQWGRQTLSYSQSPSGNPSH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX51-1", "uniprot_id": "Q9VX51_DROME", "id": "Q9VX51-1", "name": "", "aln": "MDSLESKELASISKVMENNDKASE--------NDKITGITTEEEEEVVPVKKKRTEEGGGELKEVACEKETVQREKCQDKNTCRCSQLEAEPIKDNRQLLEFRVRSRNIDWREYVLPLDTSVRTTPVYLDRQADFVGSTRRQVTEDNRRELLVCHDMMGNYLEDRHFHSSQKYDDYRFVHWSAVDYFCYFSHDYVTIPPCGWLNAAHRHGVPVVGTFIVEATAR---LDEFLASEE-SVESTVEALTRLCEHFGFEGWLVNVEVTVPLAKMPRLYRFVRQLTAATESRVPHGRVFWYDSVTDDGQLRWQNELNSRNAKFFRHSHGTLINYAWDEGHLERSAQQVRREQSPRHRVFMGLDVFGRSRKGG--FHSWETMELIAKNGFSAGIFAPGWTFETLNRFGYNIKNPRGDDQVNASFLARNEAWWSRIWPTLATHPYTS-LPFFTDFCVGSGRAKFERGWRILGEDSPFFNLSRQSLQPSVPLG---------RNAMHHFDEAYSGGCSLLVTNYER------AFRLFVTDFELDRGVLLLRYVFKIDG-------------DAVGTMFDLLVRVT----------PLRRNDQDLHLFCGDYEGSIVA--PQRCYLSPHESDLPSGLFRLHHDSSSLAAG------------WQMRDYLVKFDGPVRVQDIGVKYQRPSESSTDAKLGFVYVDGLTLEDLKDTWTDIPVYSKHMWNEQRA---------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .::*. * :* .**. . *: : : :. . * .. . *:.*****.**:**.::.: * * **. :* * ****. ***** * *:****** :****.* : ***.:* * .:..: *.:: . *:***:*:* :. : : . *:: ** . :** . *:***** ..*:* **:***..* ** ..* : ** * * *: . :::*:***.*.. * :.: :::*** * .:*..:***.*.:* : : .* .:: :* : * * * ***.:.** * * * .::: *. ** .: :*: **.**:: . . *:* . : : *:* *. .. : .* : : :*: . : . : . . : : : : . . * . : :: . . ", "identical_positions": 129, "similar_positions": 149, "identity": "16.19%" }, { "cls_id": "homologset.agr.MGI:2443793", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3C2-1", "uniprot_id": "D4A3C2_RAT", "id": "D4A3C2-1", "name": "", "aln": "-------------MEAPEVPVG-------SLIDFGTEPPTSPPLEAAPSTLQDPDGSLGDGASESETTESADSENDMG----------ESPSHPSWDQDRR----------------------------------------SSSNESFSSNQSADSAPDEETLALREFMR------------SYVEKIFSGGEDLD-------------QEEKAKFGEYCS--------------GEDGKGREWFARFVSAQRCKSKCVSEPT--------------------------FYRLVQSFAVVLFECHQMDDFGPAKNLMTMCFTYYYLGKPYLPPTEPREKPAGSIDSYLKSANSWLAEKKDIAERLLKN----TENMKGFFGGLETKLKGPLVRKNEEDENKPKDRQTKTVTVISPEDEQKGEK---VYLYTHLRQQPIWHTLRFWNAAFFDAVHCERRKRS--------------------------------PTTRGDAGEQEEKREKWCHMTQEE------------------------RDDSLRFNENITFGQLGTFTHNMLAFGLNKKLCSDFLKKQAVIGNLDEEQYKLLSDHIEQMATE---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0A7-1", "uniprot_id": "K0513_MOUSE", "id": "Q8R0A7-1", "name": "Uncharacterized protein KIAA0513", "aln": "-------------MEAPEVPVG-------SLIDFETEPPTSPPLEAAPSTLQDPDGSLGDGASESETTESADSENDMG----------ESPSHPSWDQDRR----------------------------------------SSSNESFSSNQSADSAPDEETLALREFMR------------SYVEKIFSGGEDLD-------------QEEKAKFGEYCS--------------GEDGKGREWFARFVSAQRCKSKCVSEPT--------------------------FYRLVQSFAVVLFECHQMDDFGPAKNLMTMCFTYYHLGKPQLPPTEPREKPAGSIDSYLKSANSWLAEKKDIAERLLKN----TENMKGFFGGLETKLKGPLVRKNEEDENKPKDRQTKTVTMISPEDEQKGEK---VYLYTHLRQQPIWHTLRFWNAAFFDAVHCERRKRS--------------------------------PTTRGDAGEQEEKREKWCHMTQEE------------------------RDDSLRFNENITFGQLGTFTHNMLAFGLNKKLCSDFLKKQAVIGNLDEEQYKLLSDHIEQMATE---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60268-1", "uniprot_id": "K0513_HUMAN", "id": "O60268-1", "name": "Uncharacterized protein KIAA0513", "aln": "-------------METPEVPVG-------SLIDFGPEAPTSSPLEAPPPVLQDGDGSLGDGASESETTESADSENDMG----------ESPSHPSWDQDRR----------------------------------------SSSNESFSSNQSTESTQDEETLALRDFMR------------GYVEKIFSGGEDLD-------------QEEKAKFGEYCS--------------SENGKGREWFARYVSAQRCNSKCVSEAT--------------------------FYRLVQSFAVVLFECHQMDDFGPAKNLMTMCFTYYHIGKPQLLPPESREKPAGSIDSYLKSANSWLAEKKDIAERLLKNTSARTENVKGFFGGLETKLKGPLARRNEEDENKPQEKRPRAVTAYSPEDEKKGEK---IYLYTHLKQQPIWHTLRFWNAAFFDAVHCERTKRS--------------------------------PTTRGDAGEEEEKREKWCHMTQEE------------------------RDDSLRFNENITFGQLGTFTHNMLAFGLNKKLCNDFLKKQAVIGNLDEEQYKLLSDHIEQMATE---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VM87-1", "uniprot_id": "Q9VM87_DROME", "id": "Q9VM87-1", "name": "SBF1/SBF2 domain-containing protein", "aln": "MVDAKPQPPTPGAMPGTGTPPGGFAGERSKIKLFMERTPSIGALKSKFLTVLGNSNELLNGISNKLTLSSSSSDSDYCDDDEDIPKFDESIDYTKIDFEGRRVKARRAHEEIISGRYRQPNLAPRPRLEPSRGRHAASKLGAPLRSSSGSSSSSSSSDDSSSVSLPEHMANRSHDVSSTTRSDSIESRHSGGYERARAIAGARRSEMDMQKDVQRIGEVGDTVPPHIDVQPPTEAGAGSGGRQQWAGGSNSMRLPSRSRASNSSTLTSLRDEPDQLLASPSMESTDWRHFIRSESQNSVPSWASSISLDCRAGEEPVKEFMKHFTALLFGGSPGAVDLELKSEFGVLLRLEIGRLWFTRFLTEQRHKS----KRLDSVTFGSLAQYFALALFECSECEDYGPAAVLMNLCFLFYHEVEVPGCDPYREYLFSSLRQQPIWQQARFWNAIFHDGMQAEREHRGQSQMRRQKRRQQKQQQRQAAAGAGSGAGTADGPPTKSQRKQGGDSSSSSSHQAAQSGTPAAQACTGSIPANRRPSKTSLTQAHSLRDQEDIAFRQLGALTCNMHSLGTSQELCLDFLKKNVVAHNLSKDKAKLIRDNIYRMYHETQLWGARHA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .* * .: * ..*: .*:: .: . ...* :* *:. * .*:.*:.* ** .:.. * : * :. ..* .*..*:.*: *..:::* :.* . :*. .*** : *:: ::** . . .. **: :* .: * *:. :. : * * .. :* : . * ..:: :. :.:: * : ..:. *: . * .: ::*: *. .. . **.* : .* . .* :: * . * * * . **:: *:*****: ***** *.*.::.** :*. *.*:.: : :. .. .* : :. : .*** :*:*:* ***::* ** ::* .::** *****:.* **.::: **: *:* :* * ", "identical_positions": 104, "similar_positions": 153, "identity": "16.94%" }, { "cls_id": "homologset.agr.MGI:2443796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZR76-1", "uniprot_id": "D3ZR76_RAT", "id": "D3ZR76-1", "name": "", "aln": "MRTTLWTLSLG-SLLTLRAALIGTSSEDGQGNLRLAHRQSKCDGVVLVRHQGEWGHLCNLEWTLAEASVVCRQLGCGPAVGAPKYVPLPGEMVQPWLHNVSCWGNESSLWECSLGAWSQRACPHEWVVVALCANGTFREIRLVKGHSPCAGLPEIRNVNGVDRLCGLHVEEATVFCRELECGHALQAPRQDVGVS-KYMTCKGTEPTIRNCRLNNKLRGGCNLLLDAEVVCSGHVEARLVGGDHSCSGRLEVLRGLTWGTVCHADLDLPTAHVICRELGCGMAVSTLRGAQFGQGSGPVWLEAFRCVGNESMLFHCPQEPGHHCGHNQDVALTCSEFRLVNGSSDCEGRVELQVQGAWAPLCAANWDLADAMVLCHQLNCGNAVSIPPGGHFGDGDAPIWPDVFHCVGTEPHLLHCPASTLGAHSCVLGNTASTICSGLQDTLRLRDGQSYCDGRVEISLNGSWGRVLDDIWDIRGASVVCRQLECGEAQGAYDAPAPGFRTAPVGLSQVRCLGSETHLMQCNVSTSLLVPAATLRDAGVVCS----------------GSLRMRLAAGPGRCAGR-VEVFYQGSWGTVCDDAWDLQDAQVVCRQLDCGHALSAPGNAHFGAGTGRIWMDELHCLGNESLLWKCQSGNWGQHDCRHKEDAGVFCSESVALRLRGGTSGCVGWLDVLYNGSWGAVCSNALRDISLSIMCRQLGCGDQGWLENRPSPGPGLGISWVDKIKCRK-LHNATLWQCPSAPWNPHSCTQEEEVWINCEGLPQIGSQEPAQTPNCSSPLGCLEDSVLRVLGGEDGCSGRVELWHAGSWGTVCDDSWDLLDAQVVCRQLGCGQALAALEGAAFGPGMGPVWLDEVECLGSEVTLEACQAELWGHGDCTHKEDAGVRCAVKVQLFFCPTAPSLTPPPVAEAWNLPEVACLVLG-CLLGIVFLAMIAQWCHIRDASMGSG----------MLGNLQSDGVYEDIEVVPVMKKEENAISRLLMLEDGYDDAEEP---EGQPTESEEECNGHC----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A1B0GSB0-1", "uniprot_id": "A0A1B0GSB0_MOUSE", "id": "A0A1B0GSB0-1", "name": "", "aln": "MRTTLWPLSLG-SLLTLGAALTGTSSEGDQGNLRLAHRQSTCDGVVLVRHQGEWGHLCNLEWTLAEASVVCRQLGCGPAVGAPKYVPLPGEMVRPWLHNVSCWGNESSLWECSLGAWSQRACPHEWVVVALCANGTFREIRLVKGHSPCAGLPEIMNVNGVDRLCGLHVEEATVFCRELQCGHALQAPRQDVGVS-KYMTCKGTESTIRNCRLNNKLRGGCNLLLDAEVICSGHVEARLVGGEHSCAGRLEVLRGLTWGTICHADLDLPTAHVVCRELGCGIAVSTLGGAQFGQGSGPVWLEAFRCVGNESLLFHCPREPGHHCGHEQDAALTCSEFRLVNGSSDCEGRVELQVQGTWAPVCAANWDLADAMVLCHQLNCGNAVSVPPGGHFGDGDDLIWPDIFHCVGTEPHLLHCAASTLGAHGCVLGNTASTICSGLQDILRLRDGQSYCDGRVEISLDGSWGRVLDDAWDLHGASVVCRQLGCGEAQRAYDAPAPIFRRVPVGLSQVRCLGSETRLVHCNVSTSLLVPAGTLRDAGVVCS----------------GSLRVRLAAGPGRCAGR-VELFYQGSWGTVCDDAWDLQDAQVVCRQLDCGHALSAPRNAHFGAGTGHIWMDELHCLGNESSLWKCQSGSWGQHDCRHKEDAGVFCSESVALRLRGGTSGCVGWLDVLYNGSWGAVCSNALRDISLSIICRQLGCGDQGWLENRPSSGAGLGISWVDNIKCRN-LHNATLWQCPSAPWNPHSCTQEEEVWINCEGTPQIALQDPAQTPNCSSPFGCLENSVLRVLGGEDGCSGRVELWHAGSWGTVCDDSWDLVDAEVVCRQLGCGQALAALGEASFGPGVGPVWLDEVECLGSEVTLEACQAEPWGHGDCTHKEDAGVRCAVKAQPSLCPTAPSLTPPSVAEVWKLSEIACLVLG-CLLGIVFLVMIAQWCHIRDASMGAG----------MLGHLQSEGIYEDIEVDPVPKKEENTVSRLLMLEEGYDDAEEP---EDQPTENDE----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G0T1-1", "uniprot_id": "SRCRM_HUMAN", "id": "Q4G0T1-1", "name": "Scavenger receptor cysteine-rich domain-containing protein SCART1", "aln": "MRAALWTLGLGPLLLNLWAVPIG-----GPGALRLAYRHSTCDGVVLVRHHGAWGYVCNQEWTLAEASVVCRQLGCGPAVGAPKYVPLPGEMAQPWLHNVSCRGNESSLWECSLGSWCQSPCPHAWVVVALCSNGTFRELRLVKGRSPCAGLPEIRNVNGVDRLCVLHVEEAMVFCRELGCGPVLQAPRRDVGVVRKYLACRGTEPTIRSCRLDNNFRSGCDLRLDAEVVCSGHTEARLVGGEHPCAGRLEVT----WGTVCDAALDLATAHVVCRELQCGAVVSTPEGARFGRGSGPVWTEAFRCAGNESLLFHCPRGRGSQCGHGHDAGLRCSEFRMVNGSSSCEGRVEFQVQGSWAPLCATHWDIADATVLCHQLNCGNAVAAPGGGHFGDGDAAIWPDAFHCEGTESYLWNCPVSTLGAPACAPGNTASAVCSGLAHALRLREGQSRCDGRVEVSLDGVWGRVLDDAWDLRGAGVVCRQLGCRGAQQAYDAPAPSRGSVQVALSRVRCLGTETRLTQCNVSATLQEPAGTSRDAGVVCSGEVGTASPMARRHGIPGALTLSLHREPQGAAGRGAGALHGGAWGTVCDDAWDLRDAHVVCRQLGCGRALSALGAAHFGAGAGRIWLDELGCQGHESALWQCPSAGWGRHDWRHKEDAGVFCSESVALRLRGGTCCCAGWLDVFYNGTWGAMCSNALKDLSLSIICKQLGCG--VWGVGLAGEQALPLCGHRDRLGGQHRVPQAAQLHSVAMPFPPMAPALLR---PSRAGLSEDRPQAAGEPLNCSSWLGCPEEGALRVRGGEDRCSGRVELWHAGSWGTVCDDGWDLADAEVVCRQLGCGRAVAALGAAAFGPGSGPVWLDEVGCRGSEASLWGCPAERWGRGDRAHEEDAGVRCWEPGP------GPPLPAAPFRTFWVVSVVLGSLLGLLLLGLMAFLILPRVTQAMQRGLGRSEVSPGEAIYDVIGEMPPAGLYEEIMEAEAVLQDEEDGSVVKVDTEAAVSGEVSNLLEGQSIRAEGGHSRPVSQGYDEAAFPLEEMTL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::**.*.** **.* *. * . * ****:*:*.*********:* **::** ********************************.:******** ************:*.* .*** *******:******:*****:********* ********* ****** ****** ** .*****:**** **::*:***.***.***:*::*.**:* *****:****.*******:*.*:***** ***:*.* ***.****:**** ** .*** **:**:****** *****.****:*****: * :*** :*..* *****:*****.******:****:***:**::**:*** ************: * ******** **** *** ***.:* :*..***** .*. *****::**** . ****:*** ******:**:* ******* **::**.****** * ** ******* . *.**:*****:**:* :****::* **.* ******** *:* : * * .*** . :: *:***********:**:******.**:**** ******:*:**:*** * *:** **:* *..**:** **********************. *.*****:***:***:*****:*:****:*:***** * . .. . . *.: :: : :*: :. : *: * : : . . * .: * ..:. **** :** *:..*** **** *******************.*** **:*********:*:*** *:**** ******** * ***.:* .* ** **:** :*:******* .*.*..... * :. : :** ***:: : ::.: : : .:* . ::*.: . *:**:* . ::*: * : : :. ..* . *.*. . : ", "identical_positions": 605, "similar_positions": 200, "identity": "57.78%" }, { "cls_id": "homologset.agr.MGI:2443804", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6Y7S3-1", "uniprot_id": "A6Y7S3_RAT", "id": "A6Y7S3-1", "name": "", "aln": "MALKDTGSGGSTILPISEMVSASSSPGAPLAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGDLPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEFFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNLSQGSSDALLLRGAAAGAPSSSGAHGVSGVVSGGSAPDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQ-PEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAAFVNQYR-----DDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKCDKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNLVNTQQAVSQQPNTLTLDRPSRKAPVQWMPPPDKRRNSELFQSLISKSRETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDCFPERKRQWQSELLQKYGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q50H33-1", "uniprot_id": "KCTD8_MOUSE", "id": "Q50H33-1", "name": "BTB/POZ domain-containing protein KCTD8", "aln": "MALKDTGSGGSTILPISEMVSASSSPGAPLAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGDLPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEFFQLTDLVKLLSPKVTKQNSLNDECCQSDLEDNVSQGSSDALLLRGAAAGAPSGSGAHGVSGVVGGGSAPDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQ-PEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAAFVNQYR-----DDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKRDKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNPANTQQAAAHQPNTLTLDRPSRKAPVQWMPPPDKRRNSELFQSLISKSRETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDCFPERKRQWQSELLQKYGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZWB6-1", "uniprot_id": "KCTD8_HUMAN", "id": "Q6ZWB6-1", "name": "BTB/POZ domain-containing protein KCTD8", "aln": "MALKDTGSGGSTILPISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLRGAAAAVPSGPGAHGGG---GGGGAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQ-PEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAAFVNQYR-----DDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKHDKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNPSSAQQATAHQPNTLTLDRPSKKAPVQWIPPPDKRRNSELFQTLISKSRETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDYFPERKRQWQSELLQKYGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VDH3-1", "uniprot_id": "Q9VDH3_DROME", "id": "Q9VDH3-1", "name": "", "aln": "-----------------------------------------MPEIIELNVGGVSYTTTLATLLQDKSTLLAELFGEG--------RDSLAKDSKGRYFLDRDGVLFRYILDFLRDKALHLPEGFRERQRLLREAEHFKLTAMLECIR---SERD-----------------------------ARPP----------------------GCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQCREVFGDTLNESRDPDHGGTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFIRD-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**::****** *.*. :***. .: **.:*. . *..*.:**:.*:*:****.****:**:**** * *** * *::*******.*:** ::: : :::: * * * :*:*****: :*. **.***:::**:****:* .:**************: .::*****:**. *:*****.* : *::*... .****. . : : ::: *. *.*::*:* ", "identical_positions": 113, "similar_positions": 76, "identity": "23.44%" }, { "cls_id": "homologset.agr.MGI:2443805", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZMQ2-1", "uniprot_id": "A0A8I5ZMQ2_RAT", "id": "A0A8I5ZMQ2-1", "name": "", "aln": "------------MAHFVPSPPPNCLSYKSEGRLGDQDWQAHFKVPCCG-----VDPSQLESEEAEVDVRERDTQRDREPKRARDLTLRDSCTDN----------------SMQFGTRTTAAEPGFMGTW--QNADTNLLFRMSQQVPLACAGRVLGADFCPNLEEIDQRLEVQAIRCTLVNCTCECFQPGKINLRTCDQCKHGWVAHALDKLSTQHLYHPTQVEIVQSNVVFDISSLMLYGTQAVPVRLKILLDRLFSVLKQEEVLHILHGLGWTLRDYVRGYILQDAAGKVLDRWAIMSREEEIITLQQFLRFGETKSIVELMAIQEKEGQAVAVPSSKTDSDIRTFIESNNRTRSPSLLAHLENSNPSSIHHFENIPNSLAFLLPFQYINPVSAPLLGLPPNGLLLEQPGLRLREPSISTQNEYNESSESEVSPTPYKSDQTPNRNALTS-ITN-VEPKTEPACVSPIQNSAPVSDLSKPEHP--------------------------------KSSFR--IHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLTLTSPGRPPMGFTTPPLDPVLQNPLPS-QLVFSGLKTVQ---PVPPFYRSLLTPGEMVSPPTSLPTSPIIP-----------------------TSGTIEQHPPPPSEPIVPAVMMGTHEPG-------------------ADLAPKKKPRKSSMPVKIEKEIIDTADEFDDEDDDPNDG-----------------GTVVN----DMSHGNHCH-------SQDEMSPGMSVKDFSKHNRTRCIS-------------------RTEIRRADSMTSEDQEPERDYENESESSEPKLG--EESMVEDE----------HIHSEVSDKVLMNSERADENHSEPS-HQDVIKVKEEFTDPTYDMFYMSQYGLYNG-------GGASMAALHDSFTSSLNYG-----------------------------SPQKFS---PEGDLCSSPDPK----------------ICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINLHRKLLTKELDDMGLDSSQPSLSKDLRDEFLMKIYGTQHP------LGLD-------VREDASSPAGTEDSHLNG--YGRGMAEDYMVLDLSTTSSLQSSSSIHSSRESDAGSDEGILLDDIDGASDSGESAHKAEAPTLPS----------------------SLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSRNRHSQNPNLHKNIPFTSID-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMQ3-1", "uniprot_id": "BNC2_MOUSE", "id": "Q8BMQ3-1", "name": "Zinc finger protein basonuclin-2", "aln": "------------MARFVPSPPPNCLSYKSEGRLGEQDWQAHFKVPCCG-----VDPSQLESEEAEVDVRERDTQRDREPKRARDLTLRDSCTDN----------------SMQFGTRTTAAEPGFMGTW--QNADTNLLFRMSQQVPLACAGRVLGADFCPNLEEPDQRLEVQAIRCTLVNCTCECFQPGKINLRTCDQCKHGWVAHALDKLSTQHLYHPTQVEIVQSNVVFDISSLMLYGTQAVPVRLKILLDRLFSVLKQEEVLHILHGLGWTLRDYVRGYILQDAAGKVLDRWAIMSREEEIITLQQFLRFGETKSIVELMAIQEKEGQAVAVPSSKTDSDIRTFIESNNRTRSPSLLAHLENSNPSSIHHFENIPNSLAFLLPFQYINPVSAPLLGLPPNGLLLEQPGLRLREPSISTQNEYNESSESEVSPTPYKSDQTPNRNALTS-ITN-VEPKTEPACVSPIQNSAPVSDLSKTEHP--------------------------------KSSFR--IHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLTLTSPGRPPMGFTTPPLDPVLQNPLPS-QLVFSGLKTVQ---PVPPFYRSLLTPGEMVSPPTSLPTSPIIP-----------------------TSGTIEQHPPPPSEPIVPAVMMGTHEPS-------------------ADLAPKKKPRKSSMPVKIEKEIIDTADEFDDEDDDPNDG-----------------GTVVN----DMSHDNHCH-------SQDEMSPGMSVKDFSKHNRTRCIS-------------------RTEIRRADSMTSEDQEPERDYENESESSEPKLG--EESMEGDE----------HLHSEVSEKVLMNSERPDENHSEPS-HQDVIKVKEEFTDPTYDMFYMSQYGLYNG-------GGASMAALHESFTSSLNYG-----------------------------SPQKFS---PEGDLCSSPDPK----------------ICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINLHRKLLTKELDDMSLDSSQPSLSKDLRDEFLMKIYGAQHP------LGLD-------GREDASSPAGTEDSHLNG--YGRGMAEDYMVLDLSTTSSLQSSSSVHSSRESDAGSDEGILLDDIDGASDSGESTHKAEAPTLPG----------------------SLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSRNRHSQNPNLHKNIPFTSID-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZN30-1", "uniprot_id": "BNC2_HUMAN", "id": "Q6ZN30-1", "name": "Zinc finger protein basonuclin-2", "aln": "------------MAHLGPTPPPHSLNYKSEDRLSEQDWPAYFKVPCCG-----VDTSQIESEEAEVDVRERETQRDREPKRARDLTLRDSCTDN----------------SMQFGTRTTTAEPGFMGTW--QNADTNLLFRMSQ----------------------------QAIRCTLVNCTCECFQPGKINLRTCDQCKHGWVAHALDKLSTQHLYHPTQVEIVQSNVVFDISSLMLYGTQAVPVRLKILLDRLFSVLKQEEVLHILHGLGWTLRDYVRGYILQDAAGKVLDRWAIMSREEEIITLQQFLRFGETKSIVELMAIQEKEGQAVAVPSSKTDSDIRTFIESNNRTRSPSLLAHLENSNPSSIHHFENIPNSLAFLLPFQYINPVSAPLLGLPPNGLLLEQPGLRLREPSLSTQNEYNESSESEVSPTPYKNDQTPNRNALTS-ITN-VEPKTEPACVSPIQNSAPVSDLTKTEHP--------------------------------KSSFR--IHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPS-QLVFSGLKTVQ---PVPPFYRSLLTPGEMVSPPTSLPTSPIIP-----------------------TSGTIEQHPPPPSEPVVPAVMMATHEPS-------------------ADLAPKKKPRKSSMPVKIEKEIIDTADEFDDEDDDPNDG-----------------GAVVN----DMSHDNHCH-------SQEEMSPGMSVKDFSKHNRTRCIS-------------------RTEIRRADSMTSEDQEPERDYENESESSEPKLG--EESMEGDE----------HIHSEVSEKVLMNSERPDENHSEPS-HQDVIKVKEEFTDPTYDMFYMSQYGLYNG-------GGASMAALHESFTSSLNYG-----------------------------SPQKFS---PEGDLCSSPDPK----------------ICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINLHRKLLTKELDDMGLDSSQPSLSKDLRDEFLVKIYGAQHP------MGLD-------VREDASSPAGTEDSHLNG--YGRGMAEDYMVLDLSTTSSLQSSSSIHSSRESDAGSDEGILLDDIDGASDSGESAHKAEAPALPG----------------------SLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSRNRHSQNPNLHKNIPFTSVD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKC9-1", "uniprot_id": "A0A0R4IKC9_DANRE", "id": "A0A0R4IKC9-1", "name": "", "aln": "--------------MRCDVTWAKVRRTRKRVRLGFQMMGCVPLPPLSRDRRDRLEQKSAQSEETELDVRGGVVWRERDRERARESTARASSRSSSSSSGAGGGGGEEGESSMQFSTRPASAEPGFMGTWTQQSTDSNLLFRMSQ----------------------------QAIRCTLVNCTCECFQPGKIHLRTCDQCKHGWVAHALDKLSTQHLYHPTQVEIVQSNVVFDISSLMLYGTQAVPVRLKILLDRLFSVLKQEEVLHILHGLGWTLRDYVRGYILQDAAGKVLDRWTIMSREEEIITLQQFLRFGETKSIVELMAIQEKEGQAVTVPSSKTDSGIRTFIESNNRTRSPGLLSHLENNSPSSIHHFENIPNSLAFLLPFQYINPMSAPMLGLPPNGLSIEQSGLRMREPNLPNQSDPVEASESEVSLSPFHSGQSPSRGVMGT-LPNAIEPKTEPNRASPISPTPSTLQSQQPQTPTQQTQGQQQSSSLNNHQIHHHFEKNEQSKTITHSSFSSKMHRIRRMGATSRKGRVCCNSCGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRSSSGTATPVISSTKSGFNLTSPGRPPLSFATPPLEPMIQSPLQS-PLVFPSLKSVQPVQPVPPFYRTLLSPADLVSPPVSLPTSPILP-----------------------TTANSTSLTDQQQMLAVSSLSMHVSETSPFSHR--LPTNHSTQDSIILDPMPKKKPRKSSMPVKIEKEVIDVADDYDDKDEDDDDGDSCHHHHHQPSSIHNVNGNCNNNNNGSSSSSHHCGGSGHESPSHDEMSPSQALRGMLHPEQEECTGSHGGR-------------GHGDLRCIDSFTSEDQDHERDFENESETSESKMLYRDELMDTDINQTALGKNMDKEHQGTEDDQHLRKDLDEHSHSPPSQHQPVIKIKEEINDPTYDMFCMGQYSLYNGGMAAAAAAAASMAALHESFISSMSYGT----------------------------STPKFPSQSPEGDLCSSPDPK----------------ICYVCKKSFKSSYSVKLHYKNVHLKEMHVCTVSGCNAAFPSRRSRDRHSSNINLHRKLLTKELDDIVLDPQLTTLPKQLRAEFLSKIYADHHTGLE-GVGGFDNGPPQSRGHEGMRSQVAREYSHSNG--YCHGPNDDYVVLDLSTASSVQSSGSVQSSHESDEGSDEGILLDDLEDASDTEDCTPSTGAQRLSMEGKNREEAGKEEREGETDERILHYDPSVSPSILASSGGNGTGGILCTICHKLYSNKGTLRVHYKTVHLREMHKCKIPGCNMMFSSVRSRNRHSQNPNLHKKAPYTTMID", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXJ5-1", "uniprot_id": "Q9VXJ5_DROME", "id": "Q9VXJ5-1", "name": "", "aln": "MNIGHEKHPPHFHPHPQPHPHPRAAAASEVHRLAAGGSVSPPPPPSTSS--SLLYHLPANTNAATAATVATVSASYRHPLQGHERQQNQHHHPY----------------QHQHHHHYHQHHPHLPTGG----GNVHLSRESSP----------------------------ASMVMTPSRRSSPPLPPLPLTTHPIHPHSH-SHSHPHPHPHPLPLALPLRHPLALNANAGGHQSPSRSSGSVQQTSSHAQSSAQSMSVHFSQLAHAQLHLQNQLQQKLSAAASRNNNNNNNNNNNNSSSTGSGTGTGNSTPTHDPNPMNPLSDLQN--MQPFDFRKISSAAALGAFGGPLPLPQSPTEFGQHHHHSQQQQHQHHLHRNQFFNAMAMAYHLPPPPPPPPPDSRSPPSPPPGVGQYQHQAGSGSGSGSGSGSGSSSGAGSVDDSAGKQQRNSDKVSASGSCSSSQRMTRLALSSNMRSSRKTPHSPGGGGAGGNGGSVGG------------GGGKRQWGSMPANLGTQFINPVTGKKRVQCNVCLKTFCDKGALKIHFSAVHLREMHKCTVDGCSMMFSSRRSRNRHSANPNPKLHSPHLR--RKISPHDGRSAQPHPLLLQAPNGLMAGLAPFGSFPLLTPPPDLRHHAMGGSGAGSGAGVGALELKHGQDYLQRSYLDAGRFEGQRRKLAMENEHTEDEDDDEILEVGIHMAGDDDDDEADGDEDEDDDDPDGIVVVGDEIDSMPLDHENDNDNENENDESDERSTSAVSSLSQTKEQSSPGKVVQSGLEECHTYAHAHAHALTHGHAHSLGHAHALAQMAANKRKRKSQNPVRCPVQSDENSGENSIDYDVAADLSIKKVRLPAQAAASAKESEVGESTKSIPSPPLTPYGDLRPVGLCIKTEQDHEQELDQEQGQERKREQEQEPEPDPVATASKSEMKLEEQETRPADKEDDNEEDEQVSPPVVTTLDLSRAAAAIKLEPLEEINYEADENRYVRIKQELMGGDESLAEESSDKTANHNNNNNNNNNININNSVRLESDNGLEASELEEREPEPETEIEPEHEHEHEPEPETEVEVPEVPIDKENPLKCTACGEIFQNHFHLKTHHQSVHLKLHHKCNIDGCNAAFPSKRSRDRHSSNLNLHRKLLSTSDDHGLLHAPVMPATDPLLELMSLNLNNNKSGFHHSAMVGSSAGGAGGVNPAAVGSIQAEILARICAGAHAHGLNVPLCFEALQHRFAVGHGHAGYPLIAGDGSPPSPRLFLNHGGGASPLLFAGLPRMPRFPQLTP------------------HMLAASAGNTAAAAAAAAAAAAGMGGLSPFCRRTSSDSNSQHSITPPPKRSRSQSRSPDHCVHPAHAGDTTGITEDSGQRQSPDRIS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . **. . * : ::: : . *. :.:: . . *. : .* : : :* . * :: * . :. : * : :. . .* :*. : . * * : :. . . . .* . .. . : . :: .:: * * *:: : . :: .: :. * . : :.:.: * :*: *.. . . .: : : :* . .:** :.: .: . .. *:.. *.: :.: * * ..* ... .*: : . . . ..* * * . .::..: : . . :.. : : :. . :. . : . : :...: * ** ** * *** ***:****:.****: *:**::**.*:*** ************:** * ** *. . . *. . *:: .: ..: . .: : *** : : * ..: ::: : *: * .. : . .*. . . : . . . * . : . . .:.::.* * *: :. :: .. : . . . . . :. . :::.. ::: . : . . ::* . . :*: *:: ::*. .. : : . . :. ..: : . . : : :* :: .: . * . *:* .. :. . . .. . ** : .*:*: * .* : *:. : :* *::.**** * *.: ********:*******:*:*******:.. *. *.. . .. * : :: : * . * . :: . : :* . *. :: . : . .* .. . *: : ..:.. : . :. .... : :: . . .. : :. ... . ::. . : :.: . : . ..:: : . . : :. . : ", "identical_positions": 149, "similar_positions": 379, "identity": "10.67%" }, { "cls_id": "homologset.agr.MGI:2443807", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B9EJ86-1", "uniprot_id": "OSBL8_MOUSE", "id": "B9EJ86-1", "name": "Oxysterol-binding protein-related protein 8", "aln": "-----------------------MEAALADGEPDRSSLLGDSKDVLGPS----TVVANSDEPQHLTPGKMSQRQGRDANPTPTRDLPQPSLSPAS----------------------------------------LHSQGFER----------------------GKEDISQNKDDSSLSMSKSKSESKLYNGSEKDSSTSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQ--KNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMVREGKEHDLSISSDSTHVTLYGLLRANNLHSGDNFQLNDSEIERQHFKDQDLYSDKSDKENDPEHDESDNEVLGKSE-ESDTDTSERQDDSYIDPEPVEPLKETTYMEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSRVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRG------EDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDYVNQISGKLKLGKEVLATLEGHWDSEVFINDKKTDNSEIFWNPTPDIKQWRLIRHTVKFEEQDDFESEKLWQRVTKAINAKDQTEATQEKYVLEEAQRQAARDRKTKTQEWVCKLFELDPLTGEWHYKFSDTRPWDPLNDMIQFEKDGVIQTKVKHR-TPMVSVPKMKHKP-------TRQQKKVVKGYSSPE-----PDIQ---------DSSGSEAQSVKPSTRRKKGIDLGDIQSSIESIKQTQEEIKRNIMALRNHLL--------SSTPATDYFLQQ---------KDYFVIFLLILLQVIINFIFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JXN8-1", "uniprot_id": "A0A0G2JXN8_RAT", "id": "A0A0G2JXN8-1", "name": "Oxysterol-binding protein", "aln": "-MEDLTGVRPQEFEIKLLLRGKIKIIHYSEVAEVQERLLGDSKDVLGPS----TVVANSEEPQHLTPGKMSQRQGKDAYPTPTREL-QPSLSPAS----------------------------------------LHSQGFER----------------------GKEDISQNKDDSSLSMSKSKSESKLYNGSEKDSSTSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQ--KNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSGLLKRTMMRDGKEHDLSISSDSTHVTLYGLLRANNLHSGDNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVLGKSE-ESDTDTSERQDDSYIDPEPVEPLKETTYMEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSRVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKRVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRG------EDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDYVNQISGKLKLGKEVLATLEGHWDSEVFINDKKTDNSEIFWNPTPDIKQWRLIRHTVKFEEQDDFESEKLWQRVTKAINAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWACKLFELDPLTGEWHYKFSDTRPWDPLNDMIQFEKDGVIQTKVKHR-TPMVSVPKMKHKP-------TRQQKKVAKGYSSPE-----PDVQ---------DSSGSEAQSVKPSTRRKKGIDLGDIQSSIESIKQTQEEIKRNIMALRNHLL--------SSTPATDYFLQQ---------KDYFVIFLLILLQVIINFIFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZF1-1", "uniprot_id": "OSBL8_HUMAN", "id": "Q9BZF1-1", "name": "Oxysterol-binding protein-related protein 8", "aln": "-----------------------MEGGLADGEPDRTSLLGDSKDVLGPS----TVVANSDESQLLTPGKMSQRQGKEAYPTPTKDLHQPSLSPAS----------------------------------------PHSQGFER----------------------GKEDISQNKDESSLSMSKSKSESKLYNGSEKDSSTSSKLTKKESLKVQKKNYREEKKRATKELLSTITDPSVIVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQ--KNGQWVGTVLLNACEIIERPSKKDGFCFKLFHPLEQSIWAVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRANNLHSGDNFQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSE-ESDTDTSERQDDSYIEPEPVEPLKETTYTEQSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRG------EDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGKEVLATLEGHWDSEVFITDKKTDNSEVFWNPTPDIKQWRLIRHTVKFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWSCKLFELDPLTGEWHYKFADTRPWDPLNDMIQFEKDGVIQTKVKHR-TPMVSVPKMKHKP-------TRQQKKVAKGYSSPE-----PDIQ---------DSSGSEAQSVKPSTRRKKGIELGDIQSSIESIKQTQEEIKRNIMALRNHLV--------SSTPATDYFLQQ---------KDYFIIFLLILLQVIINFMFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4JCZ0-1", "uniprot_id": "A0A0B4JCZ0_DROME", "id": "A0A0B4JCZ0-1", "name": "Oxysterol-binding protein", "aln": "MQQPATPSTPVNNAPSATPSAASGPAASAPAVASSTPIRINSAKQQGAAGGGDTLAHPATPHSHSMPGTPHQQPQSSSVPTGGHLLQLQAPLPSAGGGTGAGAVTPSGLSMGASNQSLGVSVGAASSVSGISITPPNSAGLRQSTVFDFKFKRRPSLKVLMTKLPSTDSLSNSPAPSSPGIANWASDNRDGNVADKSAADAAKLNRKESYKAQRKNYRREKKRVASELMNSLQDPAVIVLADWLKVRGTLKSWTKLWCVLKPGLLLIYKSQKTKSSHWVGTVMLTSCQVIERPSKKDGFCFKLFHPLEQSIWAPRGPDKETIGAVVQPLPTAYLIFRAPSQAAGKCWMDALELSLRCSALLLR-------------SNSSTGTAPTSSYIGEPLPVSHETQWSEADYEK-HFNDHDLDAD--------SQNEAPNAVMSGLESESESDPAEPAQDDVVDQQCVE----TSYVPFTEEEFGEQGE--QVEELAEENKSLIWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDDAFTRMKLVVQWYLSSFYKKPKGLKKPYNPILGERFRCYWQHP-SGSRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTLLPRG------ECYTATTPYAHCKGILMGTLSMELGGKINIECENTGYRTELEFKLKPFLGGADATNVVVGKIKLGKETLATINGHWDKECRVKDSKTGEETVLFKVDAETRSKRLTRYMVPLDLQEANESQRLWQRVSEAIANEDQVAATEEKTVLEERQRADAKERLSSDSVHMPDLFELDSY-GQWLYKYADLRPWDSRNDVRQYECQFKVLTQTRHKSVPIVHGAEMIHPLRSSIETLSRTQRQSPAGQPLPPGGSAVPKAKNKSLVLAPRDTNSDSSQSPQGAVKRSSSSAIKQLALAVDQVNRVLEQHTRQLNEISQRLERMQYSPPPSSMSAHSLHMLGGGVSQSTVIKSLIYALIGLAFSLILRWLFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02201-1", "uniprot_id": "OSH6_YEAST", "id": "Q02201-1", "name": "Oxysterol-binding protein homolog 6", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSKKLTVG-----------------------------------SDSHRLSKSSFSSNKSSHSATKDQPIDTDDID-------------------------EDDESGHNIILNIISQLRPGCDLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHSEKDPLKRFLYVMKWYLAGWHIAPKAVKKPLNPVLGEYFTAYWDLP-NKQQAYYISEQTSHHPPECAYFYMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLTQPNVYVRGILFGKMRIELGDHMIIKSPN--FQADIEFKTKGYVFG-TYDAIEGTVKDYDGNAYYEISGKWNDVMYLKDLKQPRSSPKVFLDTHKES-PLRPKVRPLSEQGEYESRKLWKKVTDALAVRNHPVATEEKFQIEDHQRQLAKKRIEDGVEFHPKLFRRSKPGEDLDYCIYKNIPVDE---------DPEKQIRSILQIAPILPGQQFTDKF----------------------------------------------------------------FIPAFEKIKSQKKMIENEKQNPAKQ----------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * . : . :. . .*:... . .*. :: : :: *..:.:* ::.*:*** **:::.******* :*:*::::: ..::* :* *.:. *: *::***:.:: **.:*** **:*** * . * * . .:::**:**.***** .*:: :..: : ::.**:* *** :*:::* : : :* * *. * * .: :*** *.: :***. : * . : : : :*** * :: . . . :. :.*:*:. :.* * .. .. .. * :. * **.:**::*: *: .:: **:** :*: ** *:.* . .**. . : * . * * : : : .*:: :: . : :.:.:: : .: :: ", "identical_positions": 103, "similar_positions": 163, "identity": "10.04%" }, { "cls_id": "homologset.agr.MGI:2443812", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9U0-1", "uniprot_id": "D4A9U0_RAT", "id": "D4A9U0-1", "name": "", "aln": "MELQSRSEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGSSTAVPVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVTPGRDRPPKQPPTFQKATVVSIKNPSPALPTANNTVNHVPTPSSQTQALTEPTAITSPLSSAGVAYAIISTSPSNAATITPSTTVPVASDGIKVQPLLISADKK------------------------------------------VIIIQPQVKTQPESSAEPEPPTEEPSQGAQDTK---EDQPPSKENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYSGFLETERKRLASSYLHNPLFLTARANEDPCWKGEITHDEFCAACKRGASLQPCGTCSGAYHLSCLDPPLKTAPKGVWVCPKCQRKALKKDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQSEHQQLEERDRQLASAVKKCLELKTSLLARQRGTQSSLDRIRALLRLIQGEQMLQVAVATTSPTPLLAGAWTKPSTTTTMRTSLQHPQNHN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C966-1", "uniprot_id": "PF21B_MOUSE", "id": "Q8C966-1", "name": "PHD finger protein 21B", "aln": "MELQSRSEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGSTTAVPVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVTPGRDRPPKQPPTFQKATVVSIKNPSPALPTANNTVNHVPTPSSQTQALTEPTAITSPLSSAGVAYAIISTSPSNAATITPSTTVPVASDGIKVQPLLISADKK------------------------------------------VIIIQPQVKTQPESSAEPEPPTEEPSQGAQATK---EDQPPSKENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYSGFLETERKRLASSYLHNPLFLTARANEDPCWKGEITHDEFCAACKRGASLQPCGTCSGAYHLSCLDPPLKTPPKGLWVCPKCQRKALKKDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQSEHQQLEERDRQLASAVKKCLELKTSLLARQRGTQSSLDRIRALLRLIQGEQMLQVAMATTSPTPLLAGPWTKPSTTTTMRTTLQHPQNHN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EK2-1", "uniprot_id": "PF21B_HUMAN", "id": "Q96EK2-1", "name": "PHD finger protein 21B", "aln": "MELQSRPEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGTITAVPVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKNPSPALPTANNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAVSVVSDSIKVQPLLISADNKPPPRLLSSPHPATHHCPLHPSSLPLTPPSPSLSPSPLHGIFQVIIIQPQVQTQPESTAESRPPTEEPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCLELKTSLLARQRGTQSSLDRLRALLRLIQGEQLLQVTMTTTSPAPLLAGPWTKPSVAATHPT-VQHPQGHN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.************************************: ***************************************:********************:**************.***:*.**.***:**:*::*********************:::***:*.*.**.***********:* ********:*****:**..*********** ** **:**::******************************************:**********.**:****************.******.********.*******.********:*****.***:****:**:*******************************************.**********:*****:**********************:***********:***:::****:*****.*****.::* * :****.**", "identical_positions": 428, "similar_positions": 54, "identity": "80.45%" }, { "cls_id": "homologset.agr.MGI:2443815", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5DQR4-1", "uniprot_id": "STB5L_MOUSE", "id": "Q5DQR4-1", "name": "Syntaxin-binding protein 5-like", "aln": "--MKKFNFRKVLDGLTASSPGS------GSSSGSNSGG-AGSGSVHPGGTAGLPREEIQESLTSDYFQICKTVRHGFPYQPTALAFDPVQKILAIGTRTGAIRI--------LGRPGVDCYCQH--ESGAAVLQLQFLINEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTHIVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHS-------IDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTVPHGKSQREGRKSESCKPILKVEYKTCRNS-EPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEFLTLCETPYPNEFQEPYAVAVLLEKDLIVVDLTQTNFPIFENPYPMDIHESPVTCTAYFADCP-PDLILVLYSIG--VKHKKQGYSNKEWPVSGGAWNLGAQTYPEIIITGHADGT-IKFWDASAMTLQMLYKLKTSKVFEKQKAGEGKQTCELVEEDPFAVQMIYWCPESRIFCVSGVSAYVIIYKFSRHEVTTEIVSLEVRLQCDVEDIITP-EPETSPPFPDLSSQLPPSRSLSGSTNTVSSEGVTKDSIPCLSVKTRPVRMPPGYQADLVIQLVWVDGEPPQQITSLSISSAYGIVAFGNCTGLVVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPR-------KNRQFIADNF-------------------------------------------------------CMRGLSNFYPDLTKRIRTSYQSLTELNDSP-------------------------VPLELERCK-------------------------------------------------SPTSDHVNGHCTSPTSQSCSSGKR--------------LSSADVSKVNRW--GPGRPPFR------KAQSAACMEISLPVTTEETREN----------------------------------------------SYNRSRSSSISSIDKDSKEAITALYFMESFARKNDS-TVSPCLFVGTSLGMVVLISLNLPSSDEQRFTEPVVVLPSGTFLSLKGAVLTFSCMDRTGSLMQPPYEVWRDPNNTDENEKTWKRK-------------------------------------------------------------------------------------LVMNYSSSSQE-MGDHQYTIICSEKQAKVFSLPSQTCLYVHNITETSFILQADVVVMCNSACLACFCANGHIMIMSLPSLRPMLDVNYLPLTDM-----------------------------RIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNIQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRARIALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZU84-1", "uniprot_id": "D3ZU84_RAT", "id": "D3ZU84-1", "name": "Syntaxin-binding protein 5-like", "aln": "--MKKFNFRKVLDGLTASSPGS------GSSSGSNSGG-AGSGSVHPGGTAGVLREGIQESLISECFQICKTVRHGFPYQPTALAFDPVQKILAIGTRTGAIRI--------LGRPGVDCYCQH--ESGAAVLQLQFLINEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTHIVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHS-------IDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTVPHGKSQREGRKSESCKPILKVEYKTCRNS-EPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEFLTLCETPYPNEFQEPYAVAVLLEKDLIVVDLTQTNFPIFENPYPMDIHESPVTCTAYFADCP-PDLILVLYSIG--VKHKKQGYSNKEWPVSGGAWNLGAQTYPEIIITGHADGT-IKFWDASAMTLQMLYKLKTSKVFEKQKVGDGKQTCEIVEEDPFAVQMIYWCPESRIFCVSGVSAYVIIYKFSRHEITAEIVSLEVRLQCDVEDIITP-EPETSPPFPDLSSQLPSSRSLSGSTNTVSSEGVTKDSIPCLSVKTRPVRMPPGYQADLVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCTGLVVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPR-------KNRQFIADNF-------------------------------------------------------CMRGLSNFYPDLTKRIRTSYQSLTELNDSP-------------------------VPLELERCK-------------------------------------------------SPTSDHVNGHCTSPTSQSCSSGKR--------------LSSADVSKVNRW--GPGRPPFR------KAQSAACMEISLPVTTEETREN----------------------------------------------SYNRSRSSSISSIDKDSKEAITALYFMESFARKNDS-TVSPCLFVGTSLGMVILISLNLPSSDEQRFTEPVVVLPSGTFLSLKGAVLTFSCMDRTGNLMQPPYEVWRDPNNTDENEKTWKRK-------------------------------------------------------------------------------------LVMNYSSSSQE-MGDHQYTIICSEKQAKVFSLPSQTCLYVHNITETSFILQADVVVMCNSACLACFCANGHIMIMSLPSLRPMLDVNYLPLTDM-----------------------------RIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNIQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRARIALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2K9-1", "uniprot_id": "STB5L_HUMAN", "id": "Q9Y2K9-1", "name": "Syntaxin-binding protein 5-like", "aln": "--MKKFNFRKVLDGLTASSPGS------GSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRI--------LGRPGVDCYCQH--ESGAAVLQLQFLINEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTHIVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHS-------IDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGRKSESCKPILKVEYKTCKNS-EPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEFLTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFADCP-PDLILVLYSIG--VKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGS-IKFWDASAITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVIIYKFSRHEITTEIVSLEVRLQYDVEDIITP-EPETSPPFPDLSAQLPSSRSLSGSTNTVASEGVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCNGLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPR-------KNKQFIADNF-------------------------------------------------------CMRGLSNFYPDLTKRIRTSYQSLTELNDSP-------------------------VPLELERCK-------------------------------------------------SPTSDHVNGHCTSPTSQSCSSGKR--------------LSSADVSKVNRW--GPGRPPFR------KAQSAACMEISLPVTTEENREN----------------------------------------------SYNRSRSSSISSIDKDSKEAITALYFMDSFARKNDS-TISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFSCMDRMGGLMQPPYEVWRDPNNIDENEKSWRRK-------------------------------------------------------------------------------------VVMNSSSASQE-IGDHQYTIICSEKQAKVFSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYLPLTDM-----------------------------RIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRARIALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SQE2-1", "uniprot_id": "STB5L_DANRE", "id": "Q5SQE2-1", "name": "Syntaxin-binding protein 5-like", "aln": "--MKKF--RKVLDGLTTSSPVNP-----GGSPG------CGSAAGTPSAAPTPRELEIQETLMSEHFQICKTVRHGFPYQPTALAFDPVQKILAIGSRSGGIRMYPFLSFPHLGRPGVDCHSQH--ESGAAVLQMQFLINEGALVTACADDTLHLWSLRQRLPAILHSLKFNRERITFCHLPFQSKWLYVGTERGNTHIVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPKDEGKLLIGFESGTIVMWDLRAKRADFRIYYDEAIHS-------VSWHHEGRQFMCSHSDGSLSMWNMRNTAKPFQVTFPHGKTQRDGRK-ESCKPILKVEYKTSRNSSEAFVIFSGGLSYDKAGRRPTLTIMHGKAITVLEMDYPIVDFMVLCETPYLNEVQEPYAVVVLLEKDFVVVDLTQSNFPIFENPYPMDVHESPVTCTAYFADCP-PDIIPVLYSIG--AKHKKTGYSHKEWPVSGGTWTVGSQTYPEIIITGHADGS-IKFWDATAITLQMLYKLKTSKVFEKPKTGDMGRSADLVEEDPYAVQMISWCPQSRIFCVVGISAHVILYRFSKHDANTIITSLELRLQCEMEDVISPSDTENTPCFSDPSGHSPQPQPPSPRSNTPDS---VRDSIPCLKVKDRMIRMPPGYQAELVVQLLWVDGEPPQQITCLDLNSAYGLLALGNCNGLAVVDYLQKTILLCMSTLELYGSADPFQRLTRSPR-------KNRQSTSG-------------------------------------------------------------------------------LTELSDNQ-------------------------VSLDLERSK-------------------------------------------------SPTSDHVNGHCTSPTSQPCPSGRAR------------VPGGPEGPRLARR--GPGRPPFR------KAQSAACMEVSLPVSS-LTEEN----------------------------------------------SFSRSRSSSVSSIDRETKEAVTTLQFAESYGRKSDS-LPTPCLWVGTSLGLVLIIPMSIPTDEQERQEDPVTVAPTGTVLMLKGSVLRFGFLDCGGALINSPYEVWRDQHAPDDPDRPRKRK-------------------------------------------------------------------------------------LVNFSPSSSQEACGDGHLAVVCSERQAKVFYMPSQACLYVHNITESSFVLRADVVSVSNSVCLACFCANGHIMILSLPSLRPLLDVSYLPLTDM-----------------------------RIARTFCFTNGGQALYLCSPTEIQRITYSQEMCE----TLGELFTPIETPEAQNRGFLKGFFGGNAQTFDREELFGEASAGKASRSLAQHIPGQGGIEGMKAAAGGVVGDLARARIALDERGQRLGELEERTALMMTSAETFSKHAHELMLKCKDKKWYQF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYK6-1", "uniprot_id": "Q9VYK6_DROME", "id": "Q9VYK6-1", "name": "", "aln": "--MKKFTFKGVLDGFRQS--------------------------VQPQATR--QEQEIQEQLKADHFTLKKTFRHGFPYSPTSFAFDPVQKLLAIGDKSGYIRI--------LGRPGVDAHAKHEGESECAVLFAQFLVNEGALVTVTADDTIHLWSIRQKTPRIVQSLKFQRERVTCIHLPVGSKWLYVGTEKGNIHVVHIDTFALSGYIINWNKAIEVVRTSHPGAVIALCDNPLDANKLLIAFECGLLVLWDLKAKCAELRWQAAEAVKS-------LAWHYEGKYFVSSHTDGSICSWPTKPQAKPQSQVCPHAKINKDGNA-EKCKPIYKVDLKSSATG-ETFTIFSGGMPSEKGSKSNCITVMVGKATTVLEMEHAVCDFITLCENPWPCETQEPYAIAVLLQYDLVLIDLLTPGFPCFESPYPMDLHESPVTCCTYLTDCP-SDLVPAFYSVGRTTTSKKSCFSEREWPISGGEWSPASCSYSEIVITGHQDGS-LKFWDSGAGTLQILYKLKTAKMFEKPRS--HVAHSHPESDNPLAVHLIFLCSESRRLCVAGAMGQVMLFKFRKVESTSEVLVLEIPILYENFDDIYG----TSPECDFLTGHQVQKAESSDSDKTAECS---------LKVRNGAQRKPPGFQSQLVCLTTGPNRRN-VQVTSLCISSSYGLMAYGTEYGLVIIDIIQKICLLSVACPDLYGAHDPYSRTPKSPKRIENKEEQSRSPSSDQLNDTTSPDSPSLEFVPEAGETSAHDGVATATSSRPSSPDPVVNSARETLLSGSAAATAAAAASAAVMMAKSPQRDDAAPKELQDRRKSMSWKTFNLKRQLSKVNMKIGGLNVNTDMESLKNSSIFYTPKEVSPEAATPPATEEEATPEGKEDESLDDGEMATNAGAAAAASPSPAVRGKFRSSTTDSPDEGASSSIASGIRRVDFEQPAGVEVERPNNLPLADAPAPLKPARQKFKEKSRDQRLLSVPNIKYQPRDSRGGARNLKNDVSPLMGGGGGGGGVVGASSGIGGSVAGGKKIHKLDGTFSRSRSSSMSSIDMSSSESVTCLAFIESYAKRNDILTLVPTLWIGTSFGSILTLFITMPERDVRKSQPVLITINGGPVVRLKGSITSMSFLDSYGSIIPYTFETWRDEKRDNKDRTPTKSSSRTSPTFTPTTANTLSNTSVAGGASAGGGAGGGGGAGGGAASGGAAAGGPAGGGAGAGSAAGAAGGVGSGVTSGGGMSSSSASSSGISGSVSTGLETLTDRQYIVIASEKQTKVFDVANQCCINRIQLSEMDFAVKAETITMKDGSCLATYLSNGHLMVHSLPSLKLLLDTDFLPLMELSFQTKCKQGIVDPMLSIWGQQIIVHEDTTQISKIFCFSHKGHGLYMASPTEIQKFTISSEFCQFILEMMGELYTVHEMPEQPKEGFFKGLFGGGAKLLDREELFGEQ-SGKPNRSVARHIPGP-NLEQLGQRASTAASEISRAHQLAMERGEKLNLLEERAERMANTAQDFSGTAHQLMLKYKDKKWYQL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38163-1", "uniprot_id": "SRO77_YEAST", "id": "P38163-1", "name": "Exocytosis protein SRO77", "aln": "MFKKSRHLKNVSNAIKSARVHD-----------------------------------VSNGINSKFFDTKKICTYGINGRITVTTFDYTQSLLAVATTAGEIHV--------YGQKQIEVVFTLK---NRPQIKHMRFIKGIYLIAVDEKSNIIVLSVHSKQ---ILTTVFCPNSITCIETDPSLDWMLIGLESGSILIYDVDRNQMSKLKIENFQKSVFLPKERLSPVISIQWNPRDIGTILISYEHITVIYSFIDYKVKQHFFYQLEPYAPGGDLSTNIEKKRTPKVIQSLYHPNSLHILTVHEDNSLVFWDVNSGKLIHARSIFETHVNFPNPALKDCSFTETPAIFKVSWLCQRNPEYTSLLIATKATENPCLPQEITMIDLG----------GTPMYSVTSFDAMSKYYAKPVQQKLFSLIGKAPLINFLPLPKASPYFGGCHDTNLILLLLEDG---ELETLIYPAGSFSSKASIFPRSLAWVRPTVTTCIAQSVQKNLWLGMMTIAQS-ESFLKGGIPATRNIRRHETRSALLTGHSNGSVRIWDASHS----EVTDNAVFEVNTAKVLNRATNLAIKNISFASETLELAVSSEVGDVILFKFETNKFYG--QLPKSDA------------LQLKFSRFSLDDSKTILVDVSDRGPTNVKQGFIPSTVIHAKKGAVSAIMNSNIGFVAVGFIEG----TLIILDRRGPAIIFNENIRVIS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KAGSSYVSTVHFCVMEYGDDGFSS----------ILMLCGTDIGELMTF----------------KILPATNGRFEVKFTDATKTNN----------------------------------------------------QGKILGINSFAKDTGYSCSATISKMQGLSKGIAIPGFVTISGANDIRLVSPGKSKDTHALFKYPIATSGLSFIPIIDGKGERKLSTIMIVLLINGDIKVLTVPELKEVKNLRCPVP--------------------------------------------------------------------------------------LSAQYVENSSILENGDIVIRTGKFQASLISVLNESATGTNHTADISQHTPIDTLYNPD------------------------LKIGYRPQVNS-------------------------------------LQWARGTIYCTPYQLD-----------------ELLGGIERPESKYEESAIARGCISSSSSNAARKLPPGTEDHRYARPVRSSGRSNGYGVLKSVSRAIETRLDTVETTINDYATTMGQTMN--DAMEETGRDMMKSAVGF------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12038-1", "uniprot_id": "SRO7_YEAST", "id": "Q12038-1", "name": "Exocytosis protein SRO7", "aln": "MFG-SKRLKNVKEAFKSLKGQNSETPIENSKASFKSKNSKTSTISKDAKSSSSLKIPISSNNKNKIFSLAETNKYGMSSKPIAAAFDFTQNLLAIATVTGEVHI--------YGQQQVEVVIKLE---DRSAIKEMRFVKGIYLVVINAKDTVYVLSLYSQK---VLTTVFVPGKITSIDTDASLDWMLIGLQNGSMIVYDIDRDQLSSFKLDNLQKSSFFPAARLSPIVSIQWNPRDIGTVLISYEYVTLTYSLVENEIKQSFIYELPPFAPGGDFSEKTNEKRTPKVIQSLYHPNSLHIITIHEDNSLVFWDANSGHMIMARTVFETEINVPQPDYIRDSSTNAAKISKVYWMCENNPEYTSLLISHKSISR-GDNQSLTMIDLG----------YTPRYSITSYEGMKNYYANPKQMKIFPLPTNVPIVNILPIPRQSPYFAGCHNPGLILLILGNG---EIETMLYPSGIFTDKASLFPQNLSWLRPLATTSMAASVPNKLWLGALSAAQNKDYLLKGGVRTKRQKLPAEYGTAFITGHSNGSVRIYDASHG----DIQDNASFEVNLSRTLNKAKELAVDKISFAAETLELAVSIETGDVVLFKYEVNQFYSVENRPESGD------------LEMNFRRFSLNNTNGVLVDVRDRAPTGVRQGFMPSTAVHANKGKTSAINNSNIGFVGIAYAAG----SLMLIDRRGPAIIYMENIREIS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAQSACVTCIEFVIMEYGDDGYSS----------ILMVCGTDMGEVITY----------------KILPASGGKFDVQLMDITNVTS----------------------------------------------------KGPIHKIDAFSKETKSSCLATIPKMQNLSKGLCIPGIVLITGFDDIRLITLGKSKSTHKGFKYPLAATGLSYISTVEKNNDRKNLTVIITLEINGHLRVFTIPDFKEQMSEHIPFP--------------------------------------------------------------------------------------IAAKYITESSVLRNGDIAIRVSEFQASLFSTVKEQDT----LAPVS-----DTLYING------------------------IRIPYRPQVNS-------------------------------------LQWARGTVYCTPAQLN-----------------ELLGGVNRPASKYKESIIAEGSFSERSSDDNNANHP---EHQYTKPTRK-GRNSSYGVLRNVSRAVETRWDAVEDRFNDYATAMGETMN--EAVEQTGKDVMKGALGF------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * :.: :.. . * : :*: :** .*.:**:. :* ::: *: :: . : ::: *: ...: : .: .: : : * :* . .*: :* : *. : .:: :* : : . : ..:: : .* * ..:**.:* : : : : . . : : : . : .*: : .: *. . : . : : : . . .: :: *::. . . : : *: . .*: .* ..:: : * :. :. :. ... : * . ::* . * : .. : . . .. . * .... . . : : : :: : : : : . :.. . :: . * : ... .. *:. : : : . : . : . : .* . : . * . ..: . .. : *: :.:: . : . * : :. . : : . : . . . :. : .. . : : . : . : .: *:.:: .: : . :.: . : : * : : .:. :* ::: :* : * . . . : . : .: . : : .. : . :. : : :.. . * : ", "identical_positions": 45, "similar_positions": 272, "identity": "2.93%" }, { "cls_id": "homologset.agr.MGI:2443816", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CFD4-1", "uniprot_id": "SNX8_MOUSE", "id": "Q8CFD4-1", "name": "Sorting nexin-8", "aln": "-------------------------------------------------MTGRAMDPLPSP--------AVAAAAEAEADEEADPPAT--------GPRTSQVTEWRALD-----PGRMQMPQGNPLLLSYT-----LQELLAKDTVQVELIPEKKGLFLKHVEYEVS--------SQRFKSSVYRRYNDFVVFHEVLLHKFPYRMVPALPPKRVLG------ADREFIEGRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQHKLKEAAQCVGDEFMNCKLAARAKDFLPADIQTQFAMSRELIRNVYNSFYKLRDRAERIASRAIDNAADLLIFGKELS----ALGSDTTPLPSWAALHLSTWGSLKQALKGLSVEFALLADRAAQQGKKEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYGLMKRQMMSA-AHGREP-ESVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKEMSKVWNDLKPKLSCLFAGPHSVLTPPRSPQEDGVCPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZUJ9-1", "uniprot_id": "D3ZUJ9_RAT", "id": "D3ZUJ9-1", "name": "Sorting nexin-8", "aln": "-------------------------------------------------MTGRAMDPLPSP--------AVAAAAEAEADEEADPPAT--------GPQTSQVTEWRNLD-----PRRMQMPQGNPLLLSYT-----LQELLAKDTVQVELIPEKKGLFLKHVEYEVS--------SQRFKSSVYRRYNDFVVFHEVLLHKFPYRMVPALPPKRVLG------ADREFIEGRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQHKLKEAAQCVGDEFTNCKLAARAKDFLPADIQTQFAMSRELIRNVYNSFYKLRDRAERIASRAIDNAADLLIFGKELRQVTLALGSDTTPLPSWAALHLSTWGSLKQALKGLSVEFALLADKAAQQGKKEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYGLMKRQMMSA-AHGREP-ESVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKEMSKVWNDLKPKLSCLFAGPHSVLTPPRSPQEDGMCPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y5X2-1", "uniprot_id": "SNX8_HUMAN", "id": "Q9Y5X2-1", "name": "Sorting nexin-8", "aln": "-------------------------------------------------MTGRAMDPLPAA--------AVGAAAEAEADEEADPPAS--------DLPTPQAIEPQAIVQQVPAPSRMQMPQGNPLLLSHT-----LQELLARDTVQVELIPEKKGLFLKHVEYEVS--------SQRFKSSVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLG------ADREFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLNCKLATRAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELS----AIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSATAQNREP-ESVEQLESRIVEQENAIQTMELRNYFSLYCLHQETQLIHVYLPLTSHILRAFVNSQIQGHKEMSKVWNDLRPKLSCLFAGPHSTLTPPCSPPEDGLCPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NGW9-1", "uniprot_id": "F6NGW9_DANRE", "id": "F6NGW9-1", "name": "", "aln": "---MAGDINEGSVPSYYREVHQALCSASDERVPVNVFQRVFTRTSLPITVQNQILEHVNSSDGFLSKVSLYKALALIALAQQGKPPSPKLLENFIQDFPKPQLGEPKELH-----SLKMQTVQDSPLILSLT-----LAELLKKDTIKIELTPEKKGLFLKHVEYQVT--------SERFTLTVYRRYSDFDVFHELLLQRYSYRVVPALPPKRALKGVLTSVSEREFIEGRRRALTRFLNLVARHPVFSEDELVKTFLTFSGSDVQSKLRDACRKLGDEFMTCKFATQAKDYLPADIQSQFSSSRQLIRNIHSSFQKLRDRAEKMAERSKDNATDLLMFGKELS----FLGSDESPVPILVS-GRNPWSALRHSVKGLSVDFSALSEKAARQGRREEDEVVEKLDMFLDLLQSYRDLCERHEKGVLHDHQRALQKYGIMKRQIMSATVQPKEQ-LSVEQLESRIVQQENAIQAMELRNYFSLFCLHQESQLIFTYLPITSHILASFVDSQVQGHKEMGEVWQDLHSKLKSLFG-DGNGRSPPLSPK-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40959-1", "uniprot_id": "MVP1_YEAST", "id": "P40959-1", "name": "Sorting nexin MVP1", "aln": "MDNYEGSDPWNTSSNAWTKDDDHVVSTTNSEPSLNGISGEFNTLNFSTPLDTNEEDTGFLP--------TNDVLEESIWDDSRNPLGATG------MSQTPNIAANETVIDK-NDARDQNIEESEADLLDWTNNVRKTYRPLDADIIIIEEIPEREGLLFKHANYLVKHLIALPSTSPSEERTVVRRYSDFLWLREILLKRYPFRMIPELPPKRIGS----QNADQLFLKKRRIGLSRFINLVMKHPKLSNDDLVLTFLTVR-TDLTSWRKQATYDTSNEFADKKISQEFMKMWKKEFAEQWNQAASCIDTSMELWYRITLLLERHEKRIMQMVHERNFFETLVD------NFSEVTPKLYPVQQNDTILDINNNLSIIKKHLETTSSICKQETEEISGTLSPKFKIFTDILLSLRSLFERYKIMAANNVVELQRHVELNKEKLESMKGKPDVSGAEYDRIKKIIQKDRRSIIEQSNRAWLIRQCILEEFTIFQETQFLITRAFQDWAKLNSNHAGLKLNEWEKLVT----------SIMDMPISRE-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . :. .* .. ..: . : . : :... :*. * . * * : :* **::**::**.:* *. * :* ***.** ::*:**:::.:*::* ***** ::: *:: ** .*.**:*** :** :*:* :: **:. :*: ::: .:** *:: . . :: *: : . * . . : :: *: .* : . : :* . : . . . .. :.: :. :. .: :. . :: .. .. : *:.:* *:* * :.* **:: . :. . :: : *.:: * : . ::::. * ::.. * . * :: *: :* :. : :: : :.. : : : *:.* . . * * ", "identical_positions": 74, "similar_positions": 163, "identity": "13.36%" }, { "cls_id": "homologset.agr.MGI:2443818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CGF1-1", "uniprot_id": "RHG29_MOUSE", "id": "Q8CGF1-1", "name": "Rho GTPase-activating protein 29", "aln": "-----MIAHKQKKAKKK----------------------RVWASGQP--SAAITTSEMGLKSVSSSSSFDPEYIKELVNDVRKFSHMLLYLKEAILS----DCFKEVIHIRLDELLRVLKSILSKHQNLSSVDLQSAAEVLTAKVKAVNFTEVNEENKNDIFREVFSSIETLAFTFGNILTNFLMGDVGSDSILRLPISRESKSFENISVDS--------VDLPHEKGNFSPIELDNLLLKNTDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATRSSIGIQEFMPLQSLFTNALLSDIHSSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKDLWKQQQNKLLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEQLSSSVGLAKNLNKQLEKRRRLEEEALQKVEEANEHYKVCVTNVEERRNDLENTKREILTQLRTLVFQCDLTLKAVTVNLFHMQQLQAASLANSLQSLCDSAKLYDPGQEYSEFVKATSSSEL-------------------EEKVDGNVNKQMTNSPQTSGYEPADSLEDVAR--LPDSCHKLEEDRCSNSADMTGP---SFVRSWKFG------MFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSEAGP--------NSLGAFKKTLMSKAALTHKFRKLRSPTKCRDCDGIVMFPGVECEECLLVCHRKCLENLVIICGHQKLQGKMHIFGAEFIQVAKKEPDGIPFVLKICASEIENRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQEAKKDSPEDKKHPHVSIEVNRILLKSKDLLRQLPASHFNSLHYLIAHLRRVVDHAEENKMNSKNLGVIFGPTLIRPRPTTAPVTISSLAEYSNQARLVEFLITYSQKIFDGSLQPQAVVISNTGAVAPQVDQGYLPKPLLSPDERDTDHSMKPLFFSSKEDIRSSD-CESKSFELTTSFEESERRQNALGKCDAPLLDNKVHLLFDQEHESASQKMEDVCKSPKLLLLKSNRAANSVQRHTPRTK--MRPVSLPVDRLLLLASSPTERSSRDVGNVDSDKFGKNPAFEGLHRKDNSNTTRSKVNG----FDQQNVQKSWDTQYVRNNFTAKTTMIVP----SAYPEKGLTVNTGNNRDHPG-----SKAHAEPARAAGDVS-ERRSSDSCP-ATAVRAP---------RTLQPQHWTTFYKPPNPTFSVRGTEEKTALPSIAVPPVLVHAPQIHVTKSDP-----------------DSEATLACPVQTS--GQPKESSEEPALPEGTPTCQRPRLKRMQQFEDLEDEIPQFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PQJ5-1", "uniprot_id": "RHG29_RAT", "id": "Q5PQJ5-1", "name": "Rho GTPase-activating protein 29", "aln": "-----MIAHKQKKAKKK----------------------RVWASGQL--SAAITTSEMGLKSVSSNSIFDPEYIKELVNDIRKFSHVLLYLKEAILS----DCFKEVIHIRLDELL-----HMSKHQNLNSVDLQNAAETLASKVKAVNFTEVNDENKNDLFREVFSSIETLAFTFGNILTNFLMGDVGNDSILRLPISRESKSFENISMDS--------VDLPHEKGNFSPIELDNLLLKNSDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATRSSIGIQEFMPLQSLFTNALLNDIHSSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKELWKQQQNKLLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEQLSSSVGLGKNLNKLLEKRRRLEEEALQKVEEANEHYKVCVTNVEERRNDLENTKREILTQLRTLVFQCDLTLKAVTVNLFHMQQLQAASLANSLQSLCDSAKLYDPGQEYSEFVKATSSSEL-------------------EEKVDGNVNKQIASSPQTSGYEPADSLEDVAR--LPDSCHKLEEDRCSNSADMTGP---SFIRSWKFG------MFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSEAGP--------NSLGTFKKTLMSKAALTHKFRKLRSPTKCRDCEGIVMFPGVECEECLLVCHRKCLENLVIVCGHQKLQGKMHIFGAEFIQVAKKEPDGIPFVLKICASEIESRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQEAKKDSPEDKKHPHVSIEINRILLRSKDLLRQLPASNFNSLHYLIVHLKRVVDHAEENKMNSKNLGVIFGPTLIRPRPTTAPVTISSLAEYSSQARVVEFLITYAQKIFDGSLQPQAGVIANTGAIAPQVDHGCHPKPLLSPDERDSDHSLKQLFFSSKEDIRTMD-CESKTFELTTSFEESERKQNALGKCDAPILDNKVHLLFDQELESASHKTEDTCKSPKLLLLRSDRVANSVQRPTPRTR--LRPVSLPVDRLLLLAGSPTERSSRNTGNTDSDKFGKNAAFEGLHRKDNSNTTCSKVNG----FDQQNVQKSWDKQNERNSFTAKTTVIIP----SAYAEKGLAVSTGNNRGHSSGAAQPSKAHADPARSARDTS-EHSSSDSCP-VAAVRAP---------RTLQPQHWTTFYKPPNPTFNVRGTEEKTAFPSAAVPPVLVHAPQSHVAKSDP-----------------DLEATLACPVQTS--GQPKESSEEPGLPEGTPTCQRPRLKRMQQFEDLEDEIPQFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q52LW3-1", "uniprot_id": "RHG29_HUMAN", "id": "Q52LW3-1", "name": "Rho GTPase-activating protein 29", "aln": "-----MIAHKQKKTKKK----------------------RAWASGQL--STDITTSEMGLKSLSSNSIFDPDYIKELVNDIRKFSHMLLYLKEAIFS----DCFKEVIHIRLEELLRVLKSIMNKHQNLNSVDLQNAAEMLTAKVKAVNFTEVNEENKNDLFQEVFSSIETLAFTFGNILTNFLMGDVGNDSLLRLPVSRETKSFENVSVES--------VDSSSEKGNFSPLELDNVLLKNTDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNMVKLAEATRTNIGIQEFMPLQSLFTNALLNDIESSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKELWKQEQNKMLEAENALKKAKLLCMQRQDEYEKAKSSMFRAEEEHLSSSGGLAKNLNKQLEKKRRLEEEALQKVEEANELYKVCVTNVEERRNDLENTKREILAQLRTLVFQCDLTLKAVTVNLFHMQHLQAASLADSLQSLCDSAKLYDPGQEYSEFVKATNSTE--------------------EEKVDGNVNKHLNSS-QPSGFGPANSLEDVVR--LPDSSNKIEEDRCSNSADITGP---SFIRSWTFG------MFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSETGP--------NSLGTFKKTLMSKAALTHKFRKLRSPTKCRDCEGIVVFQGVECEECLLVCHRKCLENLVIICGHQKLPGKIHLFGAEFTQVAKKEPDGIPFILKICASEIENRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQETKKNSLEDKKWPNMCIEINRILLKSKDLLRQLPASNFNSLHFLIVHLKRVVDHAEENKMNSKNLGVIFGPSLIRPRPTTAPITISSLAEYSNQARLVEFLITYSQKIFDGSLQPQDVMCSIG-----VVDQGCFPKPLLSPEERDIERSMKSLFFSSKEDIHTSE-SESKIFERATSFEESERKQNALGKCDACLSD-KAQLLLDQEAESASQKIED-GKTPKPLSLKSDRSTNNVERHTPRTK--IRPVSLPVDR-LLLASPPNERNGRNMGNVNLDKFCKNPAFEGVNRKDAATTVCSKFNG----FDQQTLQKIQDKQYEQNSLTAKTTMIMP----SALQEKGVTTSLQISGDHSINATQPSKPYAEPVRSVREAS-ERRSSDSYP-LAPVRAP---------RTLQPQHWTTFYKPHAPIISIRGNEEKPASPSAAVPPGTDHDPHGLVVKSMP-----------------DPDKASACPGQAT--GQPKEDSEELGLPDVNPMCQRPRLKRMQQFEDLEGEIPQFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PCS4-1", "uniprot_id": "RHG29_DANRE", "id": "Q6PCS4-1", "name": "Rho GTPase-activating protein 29", "aln": "-----MFRQGSNSGNKRMTSGARLSQP-IIPLSLPTASSKTLEMGRSSKTNPLN--AMGLDHNIATSGGDPEYIMQLVNDVRKFSDVLLSLKEAFHSKESQECSQHVVNERLGELVHVLKAVIGKHQALNSSEILGAAGTVIAKVKGVNFKEVNNENKSTIFGEIHTSIDTLAFTFGNVVSDFLMGDVDGGSRLGYPQARRSRSFENLSEDSRGCSQNDLADHSLSPELSTVEQVDLLLLKNDSGVESALLYAKAWSKYTKDVLAWVEKRLSLDMECAKSFAKMAESAKAVASQQDFMPFRDIYVSAFKNEIEYNHVLLQTAAALQTNKFTQPLLARKNDLDKQRKEIKEQWQRELKKMNESESALKKARLLKMQKREEYEKARSSTSRTEEEQP-AAGGR------TLEKKRRVEEEALQKAEEAQEQYKACVADLEAKKVSLSNAKSEILAQIRKLVFQCDLTLKAVTVNWFQMQQAQTMPLSVNYQALSEQAKKYEPGQRYSEFVRSLPKERVWLESLSQDITASSKTGMSLHKRSQNSTRSSHGNLSQGSATSMDNHSADEVEGNMQPCKAKIAERRSNSSIDMQVPRTQGSQRAWSSGSAGGGGMCSDSESAGGSSESRSMDSPTASPGDFKRRLPRTPSTGTMSSADDLDEREPPSPSDTGLSEMVMETASSPGPFRNAQMSKAAHTHKLRKLRAPSKCRECDSLVVFHGAECEECSLACHKKCLETLAIQCGHKKLQGRLHLFGIDFAQVVKNSPDGIPFIIKKCTSEIESRALTIKGIYRVNGAKSRVEKLCQAFENGKDLVELSDLHPHDISNVLKLYLRQLPEPLILYRYYNDVIGLAKETQN--MDKTDSAKEKSAGEQLGLSTELKRVLFKVRDLLRQLPAPHYKTLQFLITHLHRVSEQAEENKMTASNLGIIFGPTLIKPRHLEAEVSLSSLVDYPHQARMVELLIKHHQMIFDVPLSPMSPTSPTVS------QASFGS----SIQDKESKLSRHS---RSLMDIKES----AKLYKRHSSVIIPAQLMEEGKEMKTG-DHRVQTSGEGSDVNGVGLTSVDSTSVFNRPGASSR----MVQLRPQRAKPVSRPISMPIDR-LLN-----ERNSRNTVEHD-HSP---AAIEETTEPEKPTTPRHTNFYRNPFIDTQTLRRTWDRQYRHYDVTPRTAMIVANLPPSGVQKQPEISMASQSSTSRKDGTSQSGVAPISFRAARTLKPSSPGTFYRPPSGGQLKPSDLLAKSVSRAPTTTTG-AIYTTAITVLTTASTSSVMTISTAVTTPPTTPTTSVTVALTSKPTFTTVSRSVSGGAGEGLSESDLLSPVTLSPPQSPGSSTEELSPTDAKPLYQR-RSRRMQELEHREAHFV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8N7TE50-1", "uniprot_id": "A0A8N7TE50_DANRE", "id": "A0A8N7TE50-1", "name": "Rho GTPase-activating protein 29", "aln": "MFAAGMLQQSSGGLNKRSLGMARIPDSRFFPLSS---GSGSWGLSRTVKSGSLSSISSGSDNMDNMMGADPDYIMQLVNDVRRFADVLLHLKEAFNTKDHQDCLHQVVHERLGELLRVLKAVISKHHSLNSVEILSAAGTLIAKVKGVNYKEVNEDNKQTLFSEIYTSIDTLAFTFGNVVSDFLMGDVENGSASGLPQASRSRSFENLTLESGGCGP-EKDDPPGPSPPARVEQMDGALLRSDSGVESALLYAKAWSKYTKELLAWVDKRLNMDIECAKSYAKMAESAKALASQQEHMPFRDIYISAFRNDIEYSQLIMQTTAALQANKFMQPLQARKSELDKLRKEVKEQWQREQKKMHEADSALRKARLLQAQRQEEYEKARSSTSRVEEEQISGAGGK------QLEKRRKLEEEALLKAEEAQDHYKLCVTDVGVKRVDLAKTKSEILTQIRELVFQCDLTLKAVTVNWFQMQQAQVASLPINFQSLCENSKLYEPGLCYTEFVKSLPSDRSRVESFSFDISSTHNTGL---KRAVNSTPAALVHLSQVSG---DFLSADEVESHVQARTAKMPDGRSHSTTDVQALRIQGPFRVWRTSSQGGG-MCSDSESAGGSSESRSMDSPTASPGDFKRRLPRTPSTGTMSSADDLDEREPPSPSDNGLSEMVTEAASSPGPFRNTQMSKAAQTHKLRKLRAPSKCRECDSLVVFHGAECEECSLACHKKCLETLAIQCGHKKLQGKLHLFAIDFAQAAKNSPDGIPFIIKKCTSEIENRALNIKGIYRVNGAKSRVEKLCQAFENGKDLVELSDLYPHDISNVLKLYLRQLPEPLILFRYYNDFIGLAKESQSIIVDEVEASRGCPTSDTPQISVELNRVLFKIKDLLRQLPPAHYKTLQFLIQHLHRVSERADENKMTSSNLGIIFGPTLIKPRQADAEVSLSSLVDYPYQALIVELLIRHYEMIFDTPLSPLPPSSPVAE------SSPLPVKSRFTPQEKGQQLSRHS---KSLVDIKEQQQSKAKMYKRHSSVIPSMHLMDEVKEGKIRSDKDFAAVGDKSDMN--KLLSSSVPEMRNSPGLTRRNHVTRVQLRPPRPKLVSRPISMPAER-LLNLSKVDECNVKNSVEQE-ETHSRDPVIEEVSEEEKPKS-RAGNHYRKSYIDTQTLRRTWDKQYKHHDITPKTCPVDSGSNDTNVHTSSLTSSSFSEHSKSPSTVLANRPYTIAVRPGRTLRREGNISEFCPVPTAFRPP---------RTLQPPPG-TFYKPPG--GKSKSLTEVELQSVRATANSTEEEEEDDDDDDEEEEFG-VEVSVDEPEPELDQETSVDAHDTSPLPESPSSSPEELGQNETKPVYQRLRSRRMQDLEHREAHFV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17121-1", "uniprot_id": "SAC7_YEAST", "id": "P17121-1", "name": "GTPase-activating protein SAC7", "aln": "-----MPNNTLKQGSK-------------------------------------------IENVSPSKGHVPSFWKQFINNPKSMSSENITVPRSPTS--------------------------------------------------------------------------------------LSRNAQPTTLKRPPLSSRPYSYNTPTKDR-----------------------------------------KSFSKSAK------------------QNNNNNNANSGTSPHAEFKNYRDMFLS-------------------NRNGFTGRVFG---------------VTLAESLSVASAEVIVQSELVSFGR------------------------------------------------------------------------------IPIVVAKCGAYLKAN-------------------------------GLETSGIFR----------------------------------------------------------------------------------------------------------IAGNGKRVKALQYIFSSPPDYGTKFNDWETYTVHDVASLLRR------------------------YLNNLAEPLIPLSLYEQFRNPLRSRPR--------------------------------------------------------------------ILRHMLTHEVSHPNANKTNNVTVKSSRQN-----------------------------------YNDDGANDGDIEKEDAKDDEEKRRRKIRHKRRLTRDIRAAIKEYEELFVTLSNDTKQLTIYLLDLLSLFARQSQFNLMSGRNLAAIFQPSILSHPQHDMDP-----KEYELSRLVVEFLIEYSYKLLPHLLKLAK-------------------------REQQERLSTEN--------------KKNNGDKQKTDPIEIPKITSSDSPPIVSSNKNPPAIDNNNKLDHTTLSPISTSIPENSSDLQTSKMLKPPKQRRPHSK----------------------------------SFGSTPVPPDVIASNKRRTSLFPWLH---------KPGILSDTGDNGDLTATEAEGDD-------YEEENVDPYGQSPSSVHSGSLPKQHYLPIPRMNRSLSGNSTNS------------------------------SFNTRPISMILTSGNDNSADQLELLSNTHSNNERSNALPLTED-------------------------------------------DGDERNSRSRKRESWFQRLTSRSGSANRA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .* . *.: :::*: : :: : : .: : * :. : * : .. *::. : : *::** :* . : :: :. :.:: . : * * : . . : .: ::.*: : : :* :*. *** * : :.: :*.... :::: ** *: :: : . . *. * . : : . .::* * :.* * : : : : . * . .: .: :* *:: : : .. . : ::. : . .:*: *. : :*: * . ::: * *.. **. ** *::: :* . :**:** : :: *. :: * . : : :. : . . .. : . : : :.: . .. : : . . ..*. . . . * . : :: . . . : .* * :* : . ", "identical_positions": 56, "similar_positions": 180, "identity": "4.03%" }, { "cls_id": "homologset.agr.MGI:2443822", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTP0-1", "uniprot_id": "PIGZ_MOUSE", "id": "Q8BTP0-1", "name": "GPI alpha-1,2-mannosyltransferase 4", "aln": "-----------------------------MMVAAQVIWGSFSLLRVLWCLLPQTGYIHPDEFFQSPEVMAEDILGVQATRPWEFYPSSSCRTVVFPLLTSGSTFWLLRLWEELG---LWPGLVSGYMLLVGPRFLLTALSFALDWAVYDLAPLWGADRWNALCLLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSPGVVRS------------PTSKKPTPGPRWHRYLLG---------------VILAAGFFNRPTFLAFALAPLSLWGIHRASELGG-IRALIQEALVLLPGAALAAVLCVATDSWYFSSLSR---------STGVFLTPANFLYYNLDPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQQLHACLRASPQTGLSRVRGARGLLSSSKSYLLLFYFTPLLLLSAFSHQEARFLIPLLVPLVL-LCSPQTQP-----IPWKGTLVLFNILG------------------------ALIFGCLHQGGLVPGL----KYLEQIVHTPDLSGTTTHYTLLFTHTYMPPQHLLHLSG---------------LGSPVEVVDMGGAEDRVLCQALNNFSRQPACQLAG-EPWPCRLFVVTPG--------TNRHALEKCRFPLKNETLLFPHLTLEDPPALS----------------------------------SLLSGAWRKHLSLHVIELETPVVTKQPKAQP---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VD9-1", "uniprot_id": "PIGZ_HUMAN", "id": "Q86VD9-1", "name": "GPI alpha-1,2-mannosyltransferase 4", "aln": "MQICGSSVASVAAGTSFQVLGPVCWQQLDLKMAVRVLWGGLSLLRVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSCRSVLFPLLISGSTFWLLRLWEELG---PWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPPMGADRWNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWG------------PTRKEPAPGPRWRSWLLG---------------GIVAAGFFNRPTFLAFAVVPLYLWGTRGATNPG--LKSLTREALVLLPGAALTAAVFVATDSWYFSSPAT---------SRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQRLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEARFLIPLLVPLVL-LCSPQTQP-----VPWKGTVVLFNALG------------------------ALLFGCLHQGGLVPGL----EYLEQVVHAPVLPSTPTHYTLLFTHTYMPPRHLLHLPG---------------LGAPVEVVDMGGTEDWALCQTLKSFTRQPACQVAG-GPWLCRLFVVTPG--------TTRRAVEKCSFPFKNETLLFPHLTLEDPPALS----------------------------------SLLSGAWRDHLSLHIVELGEET------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MT80-1", "uniprot_id": "PIGZ_DROME", "id": "Q8MT80-1", "name": "GPI mannosyltransferase 4", "aln": "------------------MRLTTLWQNRSPGDRHLSTYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQV-LPRFQSIVSLMSG-------AIFVPLFFLSLINHQEPRFLLPVTFPLIL-LHAPKLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYP-------LAADISHVIATKPAATHVHLITSHIYSLPLHLINIPSSRVLHFNRLTHQRYRRPRDFYMYEYGGLPLDSLLQKVKLISGSCEVKKSGPSRRRYKLYLAIPASLSADLHEALVHSNASSYLNFELLKVFYPHLSTEAFPHLQGRHPCDVDAPHWAHDDLRGTCSAEQLPAFSFAYLNKQFSSFVHQLGLALYEIDVTRNKPRSVVIKKASMTETAA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04174-1", "uniprot_id": "SMP3_YEAST", "id": "Q04174-1", "name": "GPI mannosyltransferase 4", "aln": "--------------------------------MMRYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLVYGPLFTILESFPEIQ---DNPALILYSMRLQNYVMYLLCYHFLIPKLIRDER---KAVQFIKKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEK----------------NIQRSNFKNSVILG---------------LIFSFGVFNRVTFPAFIFLPCLILFWK-------FYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKG------------FVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYK--------------LDKLSTYAIISG------------LLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIM------------------------AFIMGISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYMSNNLTVSSLINTQDG--------------IESIDEVAFSVGNHHVIDLKGCDLPLLTETIRRLRLNGSITPLTLVTPN----SMTSELKKLKRDGTINLIPKRNYLFHLDLDHLDFND-------------------------------------FTTFKPGLTVYSIELL---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .*:****.**. *::: : : :: : .*** . . *: : : : . * *: : : * : : *:: .: *:****::* * ::. : . . * * *.*** ** * : : : :: : : : *: :. ..:** * : **: : ** *. .** ** :.. : :: : : . .::*. * :** :.*** ***:*: *: * . . :: *:. : ::::* **.*: : . : : : *:: . : * : . : * :. * : . : : ** : . :: * : *: ", "identical_positions": 71, "similar_positions": 117, "identity": "9.73%" }, { "cls_id": "homologset.agr.MGI:2443830", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R6S6-1", "uniprot_id": "M0R6S6_RAT", "id": "M0R6S6-1", "name": "", "aln": "-------------------------------MFRQLLRQFRKESGDQGETTPREKEDDPLSSETGRRKSFWGRLGESWAEGGVSSGGFGRKASSQT-VISKQEECLKELEELKFEIQKCQFERDELYQILDLYIYDDWDHRLDVELPILQSEHEMRMMAMQMMTNSISDAMERYKELIQVNSSYCIRHSQLLREQAQLKNKIQILLNEKRELLVEQTELPASSVEAKRFCEETGMNICDPRAKQQQV--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PST2-1", "uniprot_id": "E9PST2_RAT", "id": "E9PST2-1", "name": "", "aln": "-------------------------------MFRQLLRLFRKESVDQGETAPGQREADPLPIETGRRKSFWGRL------------GFGRKASSQN-VISTQEECLKELEGLKFEIQKCQFERDELYQILDLYIYDEWDHRLHVELPVLQSEHEMRMMAMQMMTNSISDAMERYKELIQVNSSYRIRQSQLLREQAQLKNNIQILLNEKRELLVEQTELPASSVETKRFCEEAGMNICDPRATQQQV--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZV94-1", "uniprot_id": "A0A8I5ZV94_RAT", "id": "A0A8I5ZV94-1", "name": "", "aln": "MEAKSKAETKGTAIQSLPHMWPIYIQPPKLGMFRQPLRLFQKESVDQGETTPRLKEDDLLSSSLEGRKSFWGRL------------GFGRKASSQN-VISKQEECLKELEELKFEIQKCQFERDEFYQILDLYIYDNWDHRLDVELPILQSEHEMRMMAMQMMTSSISEAMERYKELIQVNSSYRIRHSQLLREQTQLKNNIQILLNEKRELLVEQTELPASSVEVKRLCEEAGMNICVPSAKEQQV--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0L310-1", "uniprot_id": "A0ABK0L310_RAT", "id": "A0ABK0L310-1", "name": "Disks large homolog 5 N-terminal domain-containing protein", "aln": "--------------------------------------------------------------------------------------GFGRKTSSQN-VISEQEKCQKELEELKLEIQKCKFERDELYQILDLYIYDDWDLRLDVELPILQSEHERRMMAMQMMTNSISDAMERYKELIQANSSYRIRHSQLLREQAQLKNKIQILLNEKREQLVEQTELPASSVEAKRLCEEAGMNICVPSAKQQQV--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PYQ5-1", "uniprot_id": "E9PYQ5_MOUSE", "id": "E9PYQ5-1", "name": "", "aln": "-------------------------------MFSWLLRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRH------------RSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIVSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHGEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*::*:*. *: *.. :*** **::::* . : :*: **:****:: : *:..*: :::*:** *: *: * .** :*: ****: * ** *:..:**** :**.::::*****:*: ****: * * **:***:. *** . *.:** ", "identical_positions": 66, "similar_positions": 54, "identity": "25.29%" }, { "cls_id": "homologset.agr.MGI:2443834", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AM56-1", "uniprot_id": "A0A8I6AM56_RAT", "id": "A0A8I6AM56-1", "name": "", "aln": "---MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMVSSEGSTESEHLDGMEPGQKVHEKRLSNG--------SIDSTDDTSQIVELQELLEKQNYEMAQMKDRLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIRECYLQAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQMKMRTGSLIEPTISRTHLDTSAELR-YSVGSLVD-----SQSD-YRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLGSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVH-----PGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSD---------LRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHT---LPSSYHNEARSSLSASLEPDR--------------LGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKAR---------------LGQLR----------GFMETEAAAQESLGLGKLGTQAEKDR-RLKKKH----ELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTK-ESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMT-------------------TDVASSRLQRLDNSTVRTYSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BSS9-1", "uniprot_id": "LIPA2_MOUSE", "id": "Q8BSS9-1", "name": "Liprin-alpha-2", "aln": "---MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMVSSEGSTESEHLEGMEAGQKVHEKRLSNG--------SIDSTDDTSQIVELQELLEKQNYEMAQMKERLTALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIR----EAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESENFRKNLEESLHDKVSLAEEIEKLRSELDQMKMRTGSLIEPTISRTHIDTSTELR-YSVGSLVD-----SQSD-YRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLGSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVH-----PGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSD---------LRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAVRMTHT---LPSSYHNDARSSLSASLEPDS--------------LGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKAR---------------LGQLR----------GFMETEAAAQESLGLGKLGTQAEKDR-RLKKKH----ELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLTAPAKTK-ESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMT-------------------TDVASSRLQRLDNSTVRTYSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75334-1", "uniprot_id": "LIPA2_HUMAN", "id": "O75334-1", "name": "Liprin-alpha-2", "aln": "---MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLAGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNG--------SIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIR----EAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLDTSAELR-YSVGSLVD-----SQSD-YRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVH-----PGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSD---------LRKHRRKIAVVEEDGREDKATIKCETSPPPTPRALRMTHT---LPSSYHNDARSSLSVSLEPES--------------LGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKAR---------------LGQLR----------GFMETEAAAQESLGLGKLGTQAEKDR-RLKKKH----ELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTK-ESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMT-------------------TDVASSRLQRLDNSTVRTYSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q5Z2-1", "uniprot_id": "A0A8M9Q5Z2_DANRE", "id": "A0A8M9Q5Z2-1", "name": "", "aln": "---MMCEVMPTISEDTALSQRGSQSSASDPDSHFEQLMVNMLDERDRLLDTLRETQESLALAQQHLQDVIYDRDSLQRQLSSALPQ------------------EFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNAHIQRKVASGDG--AEDLLEGTD-AQKLHSKRLSNG--------SMESGDEASQVVELQELLEKQNYELAQMKERMSSLSSRVSEVEQELETARKDLIKSEDMNNKFQRDIK----EAMCQKEDMEERIVTLEKRYLSAQRESTSLHDITDKLENELANKEAFLRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGSIEERMRHLEGQLEEKNQELLRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQDSESYRKQLEDSIQEKSHISEEMEKLRSELDQYRLRAGSLTEPTLSRSHLDASGDLR-FSLGSLAE-----TQSDHYRSTKVIRRPRRGRMGLRREEQKAKSLGEHEW-RSQQLGVLGGHPFESDTEMSDIDDDDRETLFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHH----PGTSITASATASSLASSSPPSGHSTPKLTPRSPARDMERMGVMTLPSD---------LRKHRRKIAAVDEDGREDKATIKCETSPPPTPRQVRMTHT---LPASSHNDAR--LTAALETEA--------------SALSSVASSQDSLHKQPKKKGIKSSIGRLFGKKEKAR---------------LGQLGKEIMGPGQ-VGNVSDPELMGQDIAVGKLGTQAEKDR-RLKKKH----ELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMETMAAPSKTKSDSEEGSWS------QTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKKLNYDRKELERRRESSQHDIRDVLVWSNERVIRWVQSIGLRDYANILLESGVHGALIALDDNFDYSSLALLLQIPNQNTQARQILEREYNNLLALGTERRLDECDEKDFR-GPSWRRQFPPRDVHGISMMPGSAETLPAGFRLTATSAHSRRLPPEVLYEVMDDSPDDMYLDWFQVGPSAVQRLDSSTVRTYSC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PCD4-1", "uniprot_id": "M9PCD4_DROME", "id": "M9PCD4-1", "name": "", "aln": "MWNMMCDVMPTISEDS-ISQRSSQFSGEDAN--FEQLMVSMLDERDKLMDSLREAQERLNETENKLRDVEKERDSLQRQINANLPQ------------------EFATLTKELTQARETLLERDEEIGELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAAAQSGVSSEVEVLKALKSLFEHHKALDEKVRERLRLSIEKNNMMEEELSSAKEELAQYKAGVVPAGVGSGSGAG-SAATTAGGGGAENGLKEKMAGVGGSGGVNGEANELNDYAAKTHELQTIIEKQTSELSQWQRRVSDLNNKISELEENMSRVQKEHCKAQDQCAKLQRDLR----ENVAQKEDQEERITTLEKRYLNAQRESTSLHDLNEKLEQELRHKEAQLKLHEEKIGAIEEKLELSEQKLAQ---HAKLQPDMEEQLKARMEALTKAQERHGSAEDRIRGLETNLDEKTNEVVRLNQRLKMNEEHNLRLSSTVDKLLSESNERLQVHLKERMHALDEKNALTQELEKARKVAEELHHEKSEIMKELSKTRLEIENFKR---QLLQQEIAYNIQQTEALTRSLSPSSVVDPSGAFSRSNSHASFETHSLRRQSKQRLSEENALVRSMAEQEWEKLQQAAHAQQQAYELASAA-DCDDSD-VLYAAATDMMSPSGHTDAQTLAMMLQEQLDAINNEIRLIQEEKQSTEARAEELESRVG--SLEHVNLLARGRSMDRQSPPMSGRSTPNSPQRDFMQKYHTLNLPVLSSDASREELHGGMSTTGDSSSGGAASPLTARSMRLERVAQALAHSQEELRRRSIGLNPNASVAPNHTGGHMPLSSHSYGLSPLSSRYGSQESLRHYNTMGSMSMLQTPTSGVSREAAAAAVQKKKGIKSSLGRFFSKKEKVKGVKDTLPDGSPSMMSIGNLSIGLSEVDSNYDAMSMTGGMMPRIASSQGSKISSVDYGRQKKEHDYRNDLLGEAMKAGTPFALWNGPTIVAWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPQTSRT--------------------------------------TLAFGDMNHEWIGNYWLPGLGLPQYRTTFMECLVDARMLDHLTKKDLRGQLKMVDSFHRTSLQYGISMLKRLNYDRTELEHRRKMSENGLCDVLVWSNERVIRWVGSIGLKEYANNLLESGVHGGLMALDEGFDANAMGLALQIPTQNAQARQILDTEFNNLLQIATDRRPENEQ----------------RSASXCSYSPPTSSVDE--------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:*****.**: :***.** *..*.: ******.******:*:*:***:** * ::::*:** :*******:.: *** ***:*****. .** ***::***.************************************ : ********************************:*:*: . :****::*::*:. : . *. * * : ::.* . * : : * ::: *** ::***. *::* : *:: *..::.*:*:: . .:*: *::: * ***:: : :.**** ****.*******.*******:**:.:***:** :*** *: *** ::*:***:**** * :*: *::* :* *: *****:****. *:*:* ** :*:**.:*: * .** ******* ***.***:**:*******:****** **:***.* *: *. ** *: ::* : :*:.* * *::: : .* : :. . ::. * * .*:.: ::*: : : :. *:.: : .:: .:*:.::** : ** . :.:* : * **.* :: *::*****:*****************:*********:*** ****:*.**. *** :** ...::. *..* . . *: . * * : * *: ..* * : :: * : ..: :: .: . : .** :* * *. . *: .: * * : : ********:**:*.****.: :*:* . :. :. .: .. :. * * **:* :** ** : * *** *:***:*******:*********************************************************** **** ***:********** ***.*******: ******************** :**************** **:*****.***:**: *:: : *******:*****: :***::*** :*******.*:***:.** .::.* ****.**:******: *:**** :.*:** :: : *.. * * ::.. ", "identical_positions": 593, "similar_positions": 283, "identity": "43.6%" }, { "cls_id": "homologset.agr.MGI:2443841", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LUG6-1", "uniprot_id": "F1LUG6_RAT", "id": "F1LUG6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSSRQYRLSEVLQALEESRKLADADRGADQGLLGPFYNDVGMGYFQLQLFPLAVEAFLQALPLCRQAAEQATVLQNLGMTHNVLGNYWEAQEFHQKAVDLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSIRERLVAKLADATRTFVTQEKLAQAHFLPSVPGKLQTSWEASLEAKNSARVHSSAEDAQDS--------RSEEGREKK-KEGLMNMTIVLEPQRQDC--------------------------------------LGASEHLPSGGPWPRGVEHLVNTAPN----NRSSIGTKEALGRNLQRTSIQSGLCTIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYG0-1", "uniprot_id": "TTC24_MOUSE", "id": "Q8BYG0-1", "name": "Tetratricopeptide repeat protein 24", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQT----SRKAKTSARVQSSAEDAQESQ---WEGEASEGGHEKKEMEGLVNTATVLGPQRQN----------------------------------------RATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2A3L6-1", "uniprot_id": "TTC24_HUMAN", "id": "A2A3L6-1", "name": "Tetratricopeptide repeat protein 24", "aln": "MSSPNPEDVPRRPEPEPSSSNKKKKKRKWLRQEASIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRDTPVLQACAFNLGAAYVETGDPARGLELLLRAHPEEKAQGRRHGDQCFNVALAYHALGELPQALAWYHRALGHYQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQERQLRAAALALGAAAGCMLKSGRHRVGEVVQVLEKSRRLA--ERSTERRLLGHLYNDLGLGYSQLQLFPLAVEAFLQALPLCWVPGEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADTVRTRLAQVGLVQTHTLTSAPGRLQAPGGASQAEGTPAKAGSSTAGVQHRSSSGWEDEEFEEGHQKKKEERSANVPVRAGPGRPELCFLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKASIYSPGPRAHLPFVGPGPPRAEYPSILVPNGPQANRSSRWPRESLSRSRQRRPMESGICTIV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.* :: :.:*::.**:**:** :*.::: *** :***:*:** ******************* ..******:****:**.**** **:******..***************..***:*******:** *.********:*:**:*******************:************ **:**.*:**********: ** ::* :.*:: *.*.**:**: * ..*:. **: ..*. * *::** * * . * * : . *** ** * *: .*: .*** .:*:*.*. ** ::**:*:*:", "identical_positions": 191, "similar_positions": 77, "identity": "32.71%" }, { "cls_id": "homologset.agr.MGI:2443847", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K999-1", "uniprot_id": "A0A0G2K999_RAT", "id": "A0A0G2K999-1", "name": "", "aln": "-----------------MPSMWRLPIWT-------------LLALHRIHSAGAQDDVP-------------PYFKTEPVRT-QVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTRFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFE-EGEKHQSVSHGEAAVIKAPRISSFPRPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLAVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTMECVANARPLIKLHIVWKKDGALLSNG------ISDYNRRLTITNPMVSDAGYYECEAMLRSSSVAPVTRGAYLSVLEPPQFVREPERHITAEMEKVVDIPCRAKGVPPPSITWYKDAALVEVGKLT-RFKQRSDGGLQISGLLPDDTGMVQCFAHNAAGEAQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTVRYVWEKDGA-TLAVETNPRIRLDRNGSLHISQTWSGDIGTYTCRVLSAGGNDSRNAHLRVRQLPHAPEHP-VATLSTMERRAINLTWAKPFDGNSPLMRYILEMSEN-------------NAPWTILLASVDPEATSVMVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLP-VGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTAIRFTWNAPSPQFINGINQGYKLIAWEPTQEE------EVTMVTARPNFQD--SIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSSPQLVRTHEDVPGPVGHLSFNDILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWVVEAQVGMIGEGEEWLLIYQLSNEPDARSMEVPDLNPFTYYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVTLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHT-----VQDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSQAVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEIPEADRNGLVLGYKVRYKEKDSDSQARFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPATPNGIILAYQITHRLNATTANTATVEVLAPSARQYMATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPVVQQEDVKARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASAFTVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGAKWAELTSLYSMRNLTRPSLTQYELDNLTKHRRYEIRMSVYNAVGEGPLSPPQEVFVGEAVPTAAPQNVAIHSATATQLDVTWEPPPLDNQNGDIQGYKIYFWEVQR-------RNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPGSVKFSELTTTSVNVSWDAPQFPNGPLEGYRLVYEPCTPVD----------------GVSKIVTVDVKGNSPLWLKVKDLAEGMTYRFRIKAKT-FTYGPEIEANITTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ----------KASPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYSKKTDAGGNTKSGALGHGEMLSLDESSFPALELNNRRLSVKN---------------SFCRKN------GLYT-RSPPRPSPGSLHYSDEDV-TKYNDLIPAESSSLTEKPSEISDSQ-------------------GSDSEYEVDTNTQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYS-YTESDSGEPDHVTVPN--------------------SNSTQQGSLFRPKASRTPTP-QNPPNPPSQQSTLYRPPSSLAPGSRAPIAGFSSFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6V4S5-1", "uniprot_id": "SDK2_MOUSE", "id": "Q6V4S5-1", "name": "Protein sidekick-2", "aln": "----------------MFSSMWRLPLWT-------------LLALHRIHSAGAQDDVP-------------PYFKTEPVRT-QVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTRFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFE-EGEKRQSVNHGEAAVIRAPRISSFPRPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLAVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTMECVANARPLIKLHIVWKKDGAPLSSG------ISDYNRRLTIANPTVSDAGYYECEAMLRSSSVAPVTRGAYLSVLEPPQFVREPERHITAEMEKVVDIPCRAKGVPPPSITWYKDAALVEVGKLT-RFKQRSDGGLQISGLLPDDTGMLQCFAHNAAGEAQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTVRYVWEKDGA-TLAVETNPRIRLDRNGSLHISQTWSGDIGTYTCRVLSAGGNDSRNAHLRVRQLPHAPEHP-VATLSTVERRAINLTWAKPFDGNSPLMRYVLEMSEN-------------NAPWTILLASVDPEATSVMVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLP-VGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPAQEE------EVTMVTARPNFQD--SIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSSPQLVRTHEDVPGPVGHLSFNDILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWVVEAQVGVIGEGEEWLLIYQLGNEPDARSMEVPDLNPFTYYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDIAPANVTLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYGRSDGHGKTLSHT-----VQDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSQAVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEIPEADRNGLVLGYKVRYKEKDSDSQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNATTANTATVEVLAPSARQYMATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPVVQQEDVKARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASAFTVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRIRYRELLYDGLRGFTLRGINNPGAKWAELTSLYSMRNLTRPSLTQYELDNLSKHRRYEIRMSIYNAVGEGPLSPPQEVFVGEAVPTAAPQNVAIHSATATQLDVTWEPPPLDNQNGDIQGYKIYFWEVQR-------RNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTRGQTQQAAPSAPGSVKFSELTTTSVNVSWDAPQFPNGPLEGYRLVYEPCTPVD----------------GVSKIVTVDVKGNSPLWLKVKDLAEGMTYRFRIKAKT-FTYGPEIEANITTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ----------KASPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYSKKTDSGGNTKSGALGHGEMLSLDESSFPALELNNRRLSVKN---------------SFCRKN------GLYT-RSPPRPSPGSLHYSDEDV-TKYNDLIPAESSSLTEKPSEISDSQ-------------------GSDSEYEVDTNTQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYS-YTESDSGEPDHVTVPN--------------------SNSTQQGSLFRPKASRTPTP-QNPPNPQSQQSTLYRPPSSLAPGSRAPIAGFSSFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q58EX2-1", "uniprot_id": "SDK2_HUMAN", "id": "Q58EX2-1", "name": "Protein sidekick-2", "aln": "--------------------MWGLLIWT-------------LLALHQIRAARAQDDVS-------------PYFKTEPVRT-QVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFE-EGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGG------ISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLT-RFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGA-TLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHP-VATLSTVERRAINLTWTKPFDGNSPLIRYILEMSEN-------------NAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLP-VGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEE------EVTMVTARPNFQD--SIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHV-----VQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQR-------GNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVD----------------GVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT-FTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQ----------KANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGALGHSEMMSLDESSFPALELNNRRLSVKN---------------SFCRKN------GLYT-RSPPRPSPGSLHYSDEDV-TKYNDLIPAESSSLTEKPSEISDSQ-------------------GSDSEYEVDSNHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYS-YTESDSGEPDHTTVTN--------------------STSTQQGSLFRPKASRTPTP-QNPPNPPSQQSTLYRPPSSLAPGSRAPIAGFSSFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BEB8-1", "uniprot_id": "A0A8M3BEB8_DANRE", "id": "A0A8M3BEB8-1", "name": "", "aln": "------MYPACRTNAFCISPSAALAMFGNSGKARMRPCWIVILLLVLLHLASAQDDVP-------------PYFKTEPVPS-QLHLERNRLVLTCMAEGSWPLEFKWIHNDTEITRFSLEYRYLIPSLDRSHAGFYRCIVRNRVGALLQRRTEVQVAYMGSFE-EGERTQAVSQGEGAVIPAPRIRCFPQPQVTWFRDGRKIPPSSRIAITLDNTLVILSTVAPDAGRYYVQAVNDKNGENKTGQHITLSVENVGGPADPIAPTIVIPPRNTSVISGTSEVTMECVANARPLIKLSISWKKDGVLVRSG------LSDFNRRLTVLSPAVSDSGFYECEAVLRSSSVPAVSAGAYLHVLEPPQFVKEPEKHITAEMEKVVDIPCQARGVPQPDIVWYKDAVPISPVKTP-RYRVLSGGSLQVNGLLPDDTGMFQCFARNQAGEVQTNTYLAVTSIAPNITAGPSDSTVIDGMSVILHCETSGAPRPAITWQKGERVLASGSVQLPRFTLLESGSLLISPSHISDAGTYTCMASNSRGIDEASADLVVWARTRITNPPQDQSVIKGTKATMTCGVTHDPSVSVRFVWEKDGQ-VIVTQGLPRLRLDVNGTLHISQTWSGDIGTYTCRVTSVGGNDSRNAHLRVRQLPHAPENP-SAVLSSTEKRAINLTWAKPFDGNSPLIRYILEVSEN-------------NAPWTVLLANIEPESTAVTVNGLIPARSYQFRLCAVNDVGKGQFSKETDRVSLPEEPPSAPPQNVIASGRTNQSIMIQWQPPPESHQNGILRGYIIRYRLTGLP-VDIQYKNISNPDVTNLLLEDLIIWTNYEIEVAAYNGAGLGVYCHKVTEWTLQGVPTIAPGNVKAEPVNSTTIRFTWTAPNPQFINGINQGYKLLAWEPGKED------ETTVVTVRPNFQD--SVHVGHIGGLKKFSEYYTSVLCFTTPGDGPRSSPRRLRTHEDTPGAVGHLSFTEILDTSLKVSWREPNEKNGVLTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQLSSSTISSGVPPELPGPPTNLAISNIGPRTVTLQFKPGYDGKTSISRWQVEAQVGVIGENEDWVMVHQRANEPDARSLEVSGLNPYTFYRFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVTLRTASETSLWLRWVPLPEWEYNGNPDSVGYRVQYSRTGAPSKALLHV-----IADRLEREFTIEDLEEWTEYEVRVQAINGIGAGPWSQPVRGRTRESVPSCGPTNVSAFATTSSSILVRWFEVPEPDRNGLILGYKVAYKEKDSDSPLQFWTVEGNASHSVQLTGLGKYVLYEIQVLAFTRIGDGRPSTPSILERTLDDVPGPPVVILFPEVRTTSVRLIWQPPSQPNGIILAYQITYRLNSTNSNTATFDVLNSSARQYTVTGLRPESVYVFRIRAQTRKGWGEAAEALVVTTEKRARPQPTSRPTVPQENVQARSVLLSWEPGSDGLSPIRYYTVQVRELPEKNWTVHSASVSHESSSYIVDRLKPFTSYQFRVKATNDIGDSDYSQESEAITTLQDAPDESPTILTVTPHTTTSVLICWQPPPEEKINGILLGFRIRYRELLYDRLRSFSVHTISSASASWAELTSPYSMRNLSEPSLTQYELDNLLKHKRYEIRMSVYNAVGEGPTSSPQEVFVGEAVPTAPPQNVIIQSATATQFDVTWDPPPLETQNGDIQGYKIFFWEYQR-------KNETEKLRTLFLPEGGVKLKNLTGYTTYMISVAAFNAAGDGPRSPPTRGRTQQAAPSAPSFIHFSELTTTSVNVSWGEPVFPNGIIEGYRLIYEPCMPVDESSVACVDCLHSPSPPGVSKIVTVDVKGNAPLWLKIKDLADGVTYNFRIRAKT-FTYGPEVEANITTGPGEGAPGPPGEPFISRYGSALTIHWANGDPGRAPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFNMDILKQGVSYDFRVIGVNDYGYGSPSQPSPSISAQ----------KVAPFYEEWWFLVVVALVGLIFILLLVFILIIRGQSKKYAKKSDSSNNSNCNALTHGEMVSLDESRFPALELNNRRLSVKN---------------SFCRKN------GVYT-RSPPRPSPGSLNYSDEDVSTKYNDLIPAESSSLTEKPSEISDSQEALVFSFKTGGLQTLPTQWGSDSEYEVDPNRQKTHSFVNHYISDPTYYNSWRRQQKGISRAQAYN-YTESESGEPEHCAPPPPLPPLPPLPPFPPQLSSPTPQSQSQTGSLFRPKGSRTPTPSQQSSNPPSQHGTLYRPPSSLAPGSRAPIAGFSSFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O97394-1", "uniprot_id": "SDK_DROME", "id": "O97394-1", "name": "Protein sidekick", "aln": "MLKSAASSLRRRRPKTTITATLAIEMPSQPKLASLLAVLVLLCYCDSCFFCYADANLQQQNSIVQQQQLQAPRFTTHPSSSGSIVSEGSTKILQCHALGYPQPTYRWLKDGVPVGDFSSSQFYRFHSTRREDAGSYQCIARNDAGSIFSEKSDVVVAYMGIFENTTEGRLTVISGHPAIFDMPPIESIPVPSVMWQSEDGPLNYDIKYAFTHANQLIILSADENDRKGYRAKAINTQLGKEESSAFVHLNVS--GDPYIEVAPEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKDGLAVETAGVRHTLNDPWNRTLALLQANSSHSGEYTCQVRLRSGGYPAVSASARLQILEPPLFFTPMRAETFGEFGGQVQLTCDVVGEPTPQVKWFRNAESVDAHIESGRYTLNTDNTLVIKKLILDDAAMFQCLAINEAGENSASTWLRVKTSAPIMELPPQNVTALDGKDATISCRAVGSPNPNITWIYNETQLVDISS---RVQILESGDLLISNIRSVDAGLYICVRANEAGSVKGEAYLSVLVRTQIIQPPVDTTVLLGLTATLQCKVSSDPSVPYNIDWYREGQSSTPISNSQRIGVQADGQLEIQAVRASDVGSYACVVTSPGGNETRAARLSVIELPFPPSNVKVERLPEPQQRSINVSWTPGFDGNSPISKFIIQRREVSELEKFVGPVPDPLLNWITELSNVSADQRWILLENLKAATVYQFRVSAVNRVGEGSPSEPSNVVELPQEAPSGPPVGFVGSARSMSEIITQWQPPLEEHRNGQILGYILRYRLFGYNNVPWSYQNITNEAQRNFLIQELITWKDYIVQIAAYNNMGVGVYTEGSKIKTKEGVPEAPPTNVKVEAINSTAARCRWTPPNPQQINGINQGYKIQAWQRRLIDGEWRDIERRMKTVPPSLIDPLAEQTAILGGLEKFTEYNISVLCFTDPGDGVASSQVAVMTMDDVPDEVTGLHFDDVSDRSVKVLWAPPRASNGILTGYTVRYQVKDRPDTLKSFNLTADDTELTVNQLQATTHYWFEIVAWTRVGSGIPKTATIQSGVEPVLPHAPTALALSNIEAFSVVLQFTPGFDGNSSITKWKVEGQT---ARNMTWFTICEIN-DPDAETLTVTGLVPFTQYRLRLSASNVVGSSKPSEATKDFQTIQARPKHPPFNVTVRAMSAQQLRVRWIPLQQTEWYGNPR--GYNISYKQLVKTPGTIKYVPRSVVIEDHTANSHVLDSLEEWTLYEVKMNACNDVGCSKESDTAVERTREAVPSYGPLDVQANATSSTTVVVQWGEVPRQHRNGQIDGYKVFYAAADRGQQVLHKTIPNNATFTTTLTELKKYVVYHVQVLAYTRLGNGALSTPPIRVQTFEDTPGVPSNVSFPDVSLTMARIIWDVPVDPNGKILAYQVTYTLNGSAMLNYSREFP-PSDRTFRATELLPGKYYSFSCTAQTRLGWGKIATALVYTTNNRERPQAPSVPQISRSQIQAHQITFSWTPGRDGFAPLRYYTVEMREN-EGRWQPLPERVDPSLSSFTAVGLRPYMTYQFRIQATNDLGPSAFSRESVIVRTLPAAPAVGVGGLKVVPITTTSVRVQWSALETALWNGDASTGGYR---ILYQQLSDFPTALQSTP------KTDVHGINENS------VVLSDLQQDRNYEIVVLPFNSQGPGPATPPAAVYVGEAVPTGEPRAVDAAPISSTEVRLLWKPPKQSMQNGDILGYKIYYLVTYSPQALEPGRKWEEEIEVVSATATSHSLVFLDKFTEYRIQLLAFNPAGDGPRSAPITVKTLPGVPSAPLHLRFSDITMQSLEVTWDPPKFLNGEILGYLVTYETTEENE----------------KFSKQVKQKVSNTT---LRVQNLEEEVTYTFTVRAQTSVDYGPGISENVTTGPQDGSPVAPRDLILTKTLSSVEMHWINGPSGRGPILGYLIEAKKRDDSRWTKIEQTRKGMMQDFTVSYHILMPSTAYTFRVIAYNRYGISFPVYSKDSILTPSKLHLEYGYLQHKPFYRQTWFMVSLAATSIVIIVMVIAVLCVKSKSYKYKQEAQK-------TLEESMAMSIDERQELALELYRSRHGVGTGTLNSVGTLRSGTLGTLGRKSTSRPPPGVHLGKSPPRPSPASVAYHSDEESLKCYDENPDDSS-VTEKPSEVSSSE------------------ASQHSESENESVRSDPHSFVNHYAN---VNDSLRQSWKKTKPVRNYSSYTDS---EPEGSAVMS-----------------------LNGGQIIVNNMAR----------------------------SRAPLPGFSSFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . *: :: * *.*.* : .: * . :* * * * ::*:::. : ** . * : * * .** *:**.** *:::..:::* ***** ** * :* *. *:: * * .:* *.* * :. : . : *:* * *:***: * * .:*:* : *.:::. : * *. *.* :** *:: *::..* **. * ::*:****** :* * *** : . . ** *:: .. *.:* * *:. ***.. ..* .* * :**** *. . . .*: *::.* . * * *.: *:::* :. . *: ... * :. *: **:.*.**:* * *** .:.*:* *.: ** : * : *.:** .. : *.: *:*.* *** .* *.. * *. ****.**** : *** * *: :*. * :..* * * .**:* :** * :*: * *:: * *: ** *. . * ::* . *: :: :* *.*. . :.*:*:*:* * * ***::* *:* * :**..*.: *. ::*:**::*: ******: ::::: * * *:.:... : ::.* .* ****:.*** **:*. *: :: *.**:*.*:.** ..:.*.*: ..*: ***** *.*:** : ***:** * * * .::**:: *:*:::** *.:* :::****. *:*** . * :*** .* **:.*. ***: * *..*.** *********: **: : * : *. *.: * : :.. :.**:**:** ****** **** *: : * :*.*. * * * :: * *:** * * .**:**** : :: :*.:* :. *. * *. * * * * :*:.* * *.* .::**.*** * ** .** *.:*** . :*.*** **:**::**::* **.*. ... *. : : :***.:: *..* *:* * :*: *:**:* **:.::.:**:** *. .* **::*: * .* :**:** : *: *** **.:.* : :: :. : *: ....::.***** *.*:::* * :*.. *:.. ****:*** ** :*.* **:*::::*:* *:*. .*** : **** * * . . : .*:: :. ** * ***:*.:****:**:*:* * *.* :*::*.** * : **:* * .*:**: * *** *****:*: ** : . : :. .* * : .* * * . * * **** ***: * *** **::* ***..* * : :.:::*:.: :** ** **::*:****:: ** . .* . *. . *:: . *:*: :*:**::****:* * :*.** : ** ** . *.*.* ***** : *.. ** * :**: * .*. ... *. :.:.: : *.:* :.:.*** : :*: * ** :.* *:*******. *: * ::*:. : *.** . ***** ****:: : *.:..: . . .* * :* * :.: ***.*******.* :* ..**** ::**::* *::*:* * * ** : ** : **. : .** *. .*...: *::::* : :** * ::*:* . *** :. *:**** :*:* .* :: : *:: :** .* .*:.** *:***: *:. * : : : .:*.. .** ..:* ****. * ** . * .. *: : : ***.: **:* :* ..:::*:::: :* ::.:* ** :::: :* .. :*:** **** . * .* . :: **. *:: :*******.*: * .:: * * * :** :******:*.*: ...** * :. ...******* . :* *:. * . .: *. **:* **: : : *.:: : :* ****:.******", "identical_positions": 761, "similar_positions": 658, "identity": "32.33%" }, { "cls_id": "homologset.agr.MGI:2443848", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTT2-1", "uniprot_id": "LYPD6_RAT", "id": "D3ZTT2-1", "name": "Ly6/PLAUR domain-containing protein 6", "aln": "MEPSPALAWLLLLSLVADCLKAAQSRDFTVKDIIYLHPSTTPYPGGFKCFTCEKAADNYECNRWAPDIYCPRDTRYCYTQHTMEVTGNSISVTKRCVPLEECLSTGCRDSEHEGYKICTSCCEGNICNLPLPRNDTDATFATTSPINQTNGHPHCVSVIVSCLWVWLGLTL----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BPP5-1", "uniprot_id": "LYPD6_MOUSE", "id": "Q8BPP5-1", "name": "Ly6/PLAUR domain-containing protein 6", "aln": "MEPSPALAWLLLLSLVADCLKAAQSRDFTVKDIIYLHPSTTPYPGGFKCFTCEKAADNYECNRWAPDIYCPRDTRYCYTQHTMEVTGNSISVTKRCVPLEECLSTGCRDSEHEGYKICTSCCEGNICNLPLPRNETDATFATTSPINQTNGHPHCVSVIVSCLWVWLGLTL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Y78-1", "uniprot_id": "LYPD6_HUMAN", "id": "Q86Y78-1", "name": "Ly6/PLAUR domain-containing protein 6", "aln": "MEPGPALAWLLLLSLLADCLKAAQSRDFTVKDIIYLHPSTTPYPGGFKCFTCEKAADNYECNRWAPDIYCPRETRYCYTQHTMEVTGNSISVTKRCVPLEECLSTGCRDSEHEGHKVCTSCCEGNICNLPLPRNETDATFATTSPINQTNGHPRCMSVIVSCLWLWLGLML----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66IA6-1", "uniprot_id": "LYPD6_DANRE", "id": "Q66IA6-1", "name": "Ly6/PLAUR domain-containing protein 6", "aln": "MEPWPLMAWGLMLTAITGWIKAVQSRDFTEKDIIFLHPSTTPYPGGFKCFTCEDAPDNYECNRWAPDLYCPRESRYCYTHHKMSWDGNTVSVTKRCVPLEDCLQTGCSDIDHEGNRVCTACCEGNICNLPLPRNETDAIFSTTSPINRSAQSTQTLPLLLLSVSITS-LMLHSIN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** * :** *:*: ::. :**.****** ****:******************.*.***********:****::*****:*.*. **::**********:**.*** * :*** ::**:**************:*** *:******:: .: :.::: .: : * * ", "identical_positions": 110, "similar_positions": 39, "identity": "62.86%" }, { "cls_id": "homologset.agr.MGI:2443855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CBR6-1", "uniprot_id": "TSK_MOUSE", "id": "Q8CBR6-1", "name": "Tsukushi", "aln": "------------------------------------MLCSLFLLLLAVGRVQTTRPCFPGCQCEEETFG----------------LFDSFSLIRVDCSSLGPH-IVPVPIPLDTAHLDLSSNRLETVNESVLAGP----------------------GYTTLAGLDLSYNLLTSIMPSAFSR---------------------LRYLESLDLSHNGLAALPAEIFTSS-PLSDINLSHNRLREVSIS------------------AFTTHSQ-------GRALHVDLSHNLIHRLLPHPARASLP---------------APTIQSLNLSWNRFRAVP--DLRDLP-LRYLSLDGNPLATINPDAFMGLAGLTHLSLASLQGILHLPPHGFRELPGLQVLDLSGNPKLKWAGAEVFSGLGLLQELDLSGSSLVPLPEMLLHHLPALQSVSVGQD------------------------------------------------------------------------VQCRRLVREGAYHRQPGSS---------PKVVLHCGDTQESAARGPDIL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6QMY6-1", "uniprot_id": "TSK_RAT", "id": "Q6QMY6-1", "name": "Tsukushi", "aln": "------------------------------------MLCTLFLLLLALGIVQTTRPCFPGCQCEEETFG----------------LFDSFSLIRVDCSSLGPH-IVPVPIPLDTAHLDLSSNRLETVNESVLGGP----------------------GYTTLAGLDLSHNLLTSITPTAFSR---------------------LRYLESLDLSHNGLAALPAEVFTSS-PLSDINLSHNRLREVSIS------------------AFTTHSQ-------GRALHVDLSHNLIHRLLPYPARASLS---------------APTIQSLNLSWNRLRAVP--DLRDLP-LRYLSLDGNPLATINPGAFMGLAGLTHLSLASLQGILQLPPHGFRELPGLQVLDLSGNPKLKWAGAEVFSGLGLLQELDLSGSSLVPLPETLLHHLPALQSVSVGQD------------------------------------------------------------------------VQCRRLVREGAYHRQPGSS---------PKVVLHCGDTQES-ARGPDIL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WUA8-1", "uniprot_id": "TSK_HUMAN", "id": "Q8WUA8-1", "name": "Tsukushi", "aln": "-------------------------------------MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFG----------------LFDSFSLTRVDCSGLGPH-IMPVPIPLDTAHLDLSSNRLEMVNESVLAGP----------------------GYTTLAGLDLSHNLLTSISPTAFSR---------------------LRYLESLDLSHNGLTALPAESFTSS-PLSDVNLSHNQLREVSVS------------------AFTTHSQ-------GRALHVDLSHNLIHRLVPHPTRAGLP---------------APTIQSLNLAWNRLHAVP--NLRDLP-LRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSVGQD------------------------------------------------------------------------VRCRRLVREGTYPRRPGSS---------PKVALHCVDTRDSAARGPTIL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q58A48-1", "uniprot_id": "TSK_DANRE", "id": "Q58A48-1", "name": "Tsukushi", "aln": "----------------------------------MASLLCLFFSLLGLAAIGAVKNCHPQCRCEVETFG----------------LFDSFSLTKVDCSRIGPG-NTPVPIPLDTSHLDLSLNSTTSISDTMLSGP----------------------GYTTLVSLDLSSNLIAQISPKAFSK---------------------LRYLETLDLSSNALEGLSDGCFTGL-PLVELDLSENQFKEFNLD------------------LFTTRTQ-------DLPIMVDLSRNLLTSIFRRTPGHPL------------------YIKSLMLAGNQLKTVP--KLNGIP-LQYLNLDGNLISSIDTGAFDSLTELVHLSLSGLSELTLIHPGAFRSLKNLQALDLSNNSQLKTLNPNVFSGLVSLQELNLSNTAVTPLSRTVFMQMPNIKSITLGPN------------------------------------------------------------------------VHCWKTHMQGQFHRQIGQAK--------PNDILTCDN-------AGLIL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q7U5-1", "uniprot_id": "A0A6M3Q7U5_DROME", "id": "A0A6M3Q7U5-1", "name": "", "aln": "---------------MPDHTRVTATTRSRPWLCGAIPVLLLLLLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLTVNRIRTL-EFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDLSFNRIETVHPTALSD---------------------LASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLHALKSLDMSLNLVEFVRNDS-------FEGLKELLALSVQGNVMSELDLSAFEG--------------LISLKHLDLSDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDNTHLQTLHLNNNPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQFP-VDQLQKLYLGDNPLQCNCSLLWLWRLVTGNFEGVDPGMEHAAGGAVAALAKEADDEELADEATAVASTDDGVAALAAYIAEQHIVNALHTTEPSAYELATSSSNRNSGILRMDRQQIGCDIWRDKVRTRRKLLTMSEGEITCPAHIVTVVCAVITCLLVAMIGISVLYYLRF----------------------------VKRRRKLLHERGPMRTSKSIINVHDRILQGHNPGGLGLGMSMTLGGGNHVNGLGMTLNYPHHAQTLQAHHHYHQAMPLQSHGGNGNHEYQQTTLPQLDKLELERYLAAQTIANEYRALKPWELPVKEADDEPEHLYERFDHYEYPDTHTMSKLKQAASLNHSNSSAGPSPVPPSSGKPHVVYVXRGRGTGERVSQINTDIEMVGLNHLHLHHHHHNNNNNYRGCVQSAKASGQF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2J7-1", "uniprot_id": "Q9W2J7_DROME", "id": "Q9W2J7-1", "name": "", "aln": "-----------------------------------MELHWQLLTFIVCLQLLHSAGFIIQSEVRKCTYG------------------HIDKLLRIRCYDLDLK-EVPQNLKSSVEVLDLSHNRIRKLKTSSFQRY------------------------TDIKFLMLYDNMILSVEVGTFEP---------------------LTSLQEIDLSNNGLTTIPLELFQLP-RLRNLYIDSNELTSLNLQ------------------ALEKPIR-------APLEYLNVAG---CELQELPDLGILP-----------------KLWQLNASMNPLQNFRIDSLANMCHLQVIDLTKSQLSQCGCQQVTNHLMMLGASPKFVPVCLEALDIRECPLPYNRTIHSPTFASCQTTLQFAETRSFWLFGAGCFGGVCFVLLIVIFCVIHCRRKRAQRRK----------------------------------------------------------------------RNAQKRKPFVISPRNAINNRQP--------EDEPLHCDIARK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS84-1", "uniprot_id": "Q9VS84_DROME", "id": "Q9VS84-1", "name": "", "aln": "MTSLVYTVFHLASLQCSVRPEISPCTCETGKAWNHVELSCEKLESFNAVVDSLANKLNADTNIDLKITHSQLDDLEMR---SFTDMNFNLYKLRMQWNSLKSLPEVPFRGLSNVTYLSIGDNDLDEIPKHALSHMPSLLTLDIGRCKIRAVQQEDFRGIQRVTNLILVSNIITRLDRGSFPKSLLILHLGRNQLESLNGSLHDLHNLESLFINANNITSLDDELPDGG-QLRLLMAHNNRLERLPANMAGMHSLETVHIHCNQLRSFDRVLRNAVNLSEVMADNNELEYLAQDEFASCSKVETLQMGCNHIKSLNSSLLPILKLKNANFSFNDIEEFSMAELHGLRSLKTLQLSSNRIQRLLPDPRG-VQELMLVNLDLDNNRIDSLNGALAGLGNLRILNLAGN-RLEHLQVGDFDGMIRLDILDLTGNQLAELKPLEMTLLPSLKILKVAYN-------------------------------------------------NITKLEQDFKGLPVLCQANLTNNQISTISSELVTNTRCKNHNVPGKLEIHLDDNPIMCDVGLNELCRLMAVQEARIRGRSQCFENDQEVCTVLPMLYNVNLPIMVTNLKLTGREVPKPMVRVIVPSLIKANNELLPPLIATLGNPVLISTDLVNPVISPLPPPLLLATTTPPPPLPLPVESEVEKNESTTANPVPTNYTQETTTTTSTTTTTTTTETSSQVAPIEIITTTAPTTTTTSTTTPKPNETLPVIVELQDPNPPDTTVNQTALVPPVVLDPLQQDLERERERERERELERDLDHEAVAKTEYETVEYIPNLVQPPVGSDALTPPPSKANALEEDSESVHSNSVHAEYPHAAQSLQIPEEPPEE----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . .: : . . *.:. * : : : * * * : : :: * * : :. * : : * : *.: . . : : . : : : * : . .* : * :.* . : : : :. . : . * : : : . . : * ", "identical_positions": 16, "similar_positions": 56, "identity": "1.83%" }, { "cls_id": "homologset.agr.MGI:2443858", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LF07-1", "uniprot_id": "A0ABK0LF07_RAT", "id": "A0ABK0LF07-1", "name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "aln": "-----------------------------------------------------------MANENHGSPR--------------------EEASLLSHSPGTSNQNQPCSPKPVRLV----------------QDLPEELVHAGWEKCWSRRESRPYYFNRFTNQSLWEMPVLGQHDVLSDPLGLNATPLPQDSTLVETPPVENKPRKRQLSE--EQPSGNGVKKPKIEIPVTPTSQSVPSSPSIPGTPILKIWG-ASTEDKQ-------AALLRPTEVYWDLDIQTNAVIKHRGPSEVLPPHPEVELLRSQLILKLRQHYRELCQQREGIEPPRESFNRWMLERKVVDKGCDPLLPSNCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRLLFKYAEAARRLIESRSASPDSRKVVKWNVEDTFSWLRKEHSASKEDYMDRLEHLRRQCGPHVSAAAKDSVEGICSKIYHISLEYVKRIREKHLAILKENNIPEE-VEASELEPRLVYCYPVRLAVSAPPMPSVEMHMENSVVCIRYKGEMVK------VSRSYFSKLWLLYRYSCVDDSAFERFLPRVWCLLRRYQMMFGVGLY---EGTGLQGSLPVHVFEALHRLFGVSFECFASPLNCYFRQYCSAFPDTDGYFGSRGPCLDFTPLSGSFEANPPFCEELMDAMVSHFEKLLESSPEPLSFIVFIPEWREPPTPALTRMEQSRFKRHQLVLSAFEHEYRSGSQHICKKEEMHYKAVHNTAVLFLQNDPGFAKWGPTPERLQELTAAYK-----------------------QSGR---SHGSSSSSSSSSS--EAKDRDSGREQGPS---REPHPT-------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59114-1", "uniprot_id": "CAPAM_MOUSE", "id": "P59114-1", "name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "aln": "-----------------------------------------------------------MANENHGSPR--------------------EGASLLSHSPGTSSQSQPCSPKPVRLV----------------QDLPEELVHAGWEKCWSRRESRPYYFNRFTNQSLWEMPVLGQHDVLSDPLGLNATPLPQDSSLVETPPVENKSRKRQLSE--EQPSGNGVKKPKIEIPVTPTSQSVPSSPSIPGTPTLKIWG-SSTEDKQ-------AALLRPTEVYWDLDIQTNAVIKHRGPSEVLPPHPDVELLRSQLILKLRQHYRELCQQREGIEPPRESFNRWMLERKVVDKGCDPLLPSNCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRLLFKYAEAARRLIESRSASPDSRKVVKWNVEDTFSWLRKEHSASKEDYMDRLEHLRRQCGPHVSAAAKDSVEGICSKIYHISLEYVKRIREKHLAVLKENNIPEE-VEASELEPRLVYCYPVRLAVSAPPMPSVEMHVENSVVCIRYKGEMVK------VSRSYFSKLWLLYRYSCVDDSAFERFLPRVWCLLRRYQMMFGVGLY---EGTGLQGSLPVHVFETLHRLFGVSFECFASPLNCYFRQYCSAFPDTDGYFGSRGPCLDFTPLSGSFEANPPFCEELMDAMVSHFEKLLESSAEPLSFIVFIPEWREPPTPALTRMEQSRFKRHQLVLPAFEHEYRSGSQHICKKEEMHYKAVHNTAVLFLQNGPGFAKWGPTPERLQELTAAYK-----------------------QSGR---SHGSSSSSSSSSSSSEAKDRDSGREQGPS---REPHPT-------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4Z3-1", "uniprot_id": "CAPAM_HUMAN", "id": "Q9H4Z3-1", "name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "aln": "-----------------------------------------------------------MANENHGSPR--------------------EEASLLSHSPGTSNQSQPCSPKPIRLV----------------QDLPEELVHAGWEKCWSRRENRPYYFNRFTNQSLWEMPVLGQHDVISDPLGLNATPLPQDSSLVETPPAENKPRKRQLSE--EQPSGNGVKKPKIEIPVTPTGQSVPSSPSIPGTPTLKMWG-TSPEDKQQ------AALLRPTEVYWDLDIQTNAVIKHRGPSEVLPPHPEVELLRSQLILKLRQHYRELCQQREGIEPPRESFNRWMLERKVVDKGSDPLLPSNCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRLLFKYAEAARRLIESRSASPDSRKVVKWNVEDTFSWLRKDHSASKEDYMDRLEHLRRQCGPHVSAAAKDSVEGICSKIYHISLEYVKRIREKHLAILKENNISEE-VEAPEVEPRLVYCYPVRLAVSAPPMPSVEMHMENNVVCIRYKGEMVK------VSRNYFSKLWLLYRYSCIDDSAFERFLPRVWCLLRRYQMMFGVGLY---EGTGLQGSLPVHVFEALHRLFGVSFECFASPLNCYFRQYCSAFPDTDGYFGSRGPCLDFAPLSGSFEANPPFCEELMDAMVSHFERLLESSPEPLSFIVFIPEWREPPTPALTRMEQSRFKRHQLILPAFEHEYRSGSQHICKKEEMHYKAVHNTAVLFLQNDPGFAKWAPTPERLQELSAAYR-----------------------QSGR---SHSSGSSSSSSSE---AKDRDSGREQGPS---REPHPT-------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKJ1-1", "uniprot_id": "CAPAM_DANRE", "id": "A0A0R4IKJ1-1", "name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "aln": "-----------------------------------------------------------MTSENHTTIK--------------------ADSALVMSPTGSTSQAAPFSPSTSKPI----------------QELPDELIQAGWSKCWSKRENRPYYFNRFTNQSLWEMPVLGQHDVISDPLGLNAAPASGEANADAG--LGNGQRKRHPSEDASQAGPNSFKRPKVEIPATPTTPTVPISPSTPG---VKPWVNTTTDEKQGQASTPAPAPYRPSVVYWDLDIQTNAVIRERAPADHLPPHPEIELQRAQLTTKLRQHYHELCSQREGIEPPRESFNRWLLERKVVDKGLDPLLPSECDPVISPSMFREIMNDIPIRLSRIKYKEEARKLLFKYAEAAKKMIDSRNATPESRKVVKWNVEDTMNWLRRDHSASKEDYMDRLEHLRKQCGPHVASVAKDSVEGICSKIYHISAEYVRRIRQAHLTLLKECNISVDGTESAEVQDRLVYCYPVRLSIPAPPQTRVELHFENDIACLRFKGEMVK------VSRGHFNKLELLYRYSCIDDPRFEKFLSRVWCLIKRYQVMFGSGVN---EGSGLQGSLPVPVFEALNKQFGVTFECFASPLNCYFKQFCSAFPDIDGFFGSRGPFLSFSPASGSFEANPPFCEELMDAMVTHFEDLLGRSSEPLSFIIFVPEWRDPPTPALTRMEASRFRRHQMTVPAFEHEYRSGSQHICKREEIYYKAIHGTAVIFLQNNAGFAKWEPTTERIQELLAAYK-----------------------VSGRSLPSPGPSSTNTGEKDSKPAPERTAPSQDNSSPVDKTAQDTTNT----------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPB7-1", "uniprot_id": "Q9VPB7_DROME", "id": "Q9VPB7-1", "name": "", "aln": "MAANNNNSIIHNLGAGTEGLLSSVIASTGTPGMGSSPVPSRASSSSASSAAQSAWDQLTASASNNMSPSPTAGAPTVTGPILPDNLGVGAGSSPVASCSSPSTPTKTHAPSPLESMGHTPQGPPTLGPGGYGEELTAELVNQGWRKFWSKRENRPYYWNKVTGESLWEMPGTRPFDPLTDPLGICHAGGP-------TPIIPNMHQQQQHQH------HHLKRRPSDDMHIHPNQHHMGGGP------PMKKFV----------LAGP-----------WDLEVCTNAVIVERPPTLLPQPHPEVEALRAAFTMKLLKTYEDLCMRRENIKAPRDSFNRWLMERKVIDTGCDPLLPSSCMPEISSSMYREIMSDIPIKIVKPKFTGDARKQLSRYAEAAKQIIESRSAPAESKKVVKWNVEDTFQWLRRTVGASYEDFQDRLAHLKRQCEPHLVETVKSSVETLCVKIYHLSADHARKIRERHSQLLKEHGIPEPTPPPPPPHLKKVWCYPIQFAVPSPRMPTIEYLQDRDHMIIKYTPATINQPDAQYINLTYLQKLEQLYRHNCFDDKKFDLFIGRVWCLLKRYQTFLGNALNSSQEAELTQAALPVPVFECLHRQFGVSFECFASPFNSYFRQYCSAFADTDAYFGSRGPFLDFKPVSGSFQVNPPHCEELIEASLLHIDKLLTDTMEPLSFIVFLPEWKS-----ISKLDDSMYKRRSMVVLGMAHEYRHGYQHMLQKSDVLIKCMQGTQVVWLQNSAGYARWGPNEIRVEALREAFRPQRDRERERAAAAAAAAGVTSSQQSPSTPPSAASTAPTTNSCTISGVNSNSSSTATTTSTSSSPSLTTTSSSMSPLSPHTPTGNPPPQFPMTISNTSSSSNLVAASPTMSVQSDCSSPSSSTMSLSPAPASGGYPDGVTSATAAAVSITATTTTSAAGAGSAFGQANSISSSASTQAVINSAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*: : :: : ...:. . :*.. . : ::*. **:: ** * **:**.****:*:.*.:****** .* ::****: : . * :::: .. : ::*. :: *. : .* :* : ***:: ***** .* *: ***::* *: : ** : *.:** :**.*:.**:*****::****:*.* ******.* * :*.**:****.****:: : *: :*:: * :*****:::*:**.*..:*:**********:.***: .** **: *** **::** **: ..*.*** :* ****:* ::.::**: * :*** .*. .. . : *:***:::::.:* . :* :.. :::. :: :. ::.** ***:.*.** *: *: *****::*** ::* .: *. *.:*** *** *:: ***:*******:*.**:*:****.* *.:****** *.* * ****:.***.****::* : *:: ** : ******:*:***:. ::::: * ::*:.: : .: **** * **: ::.:: *.::.* *::***..*:*:* *. *:: * *:: * * .. :..:.. . .. : .* . * ", "identical_positions": 259, "similar_positions": 231, "identity": "26.84%" }, { "cls_id": "homologset.agr.MGI:2443860", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZV56-1", "uniprot_id": "D3ZV56_RAT", "id": "D3ZV56-1", "name": "RING finger protein 150", "aln": "--MTMSLIQACRSLALS--TWLLSFCFVHLLCLDFTVAEK------------------------EEWYTAFVNITYTE--PESGAAVAGGGGGAELHTEKSECGRYGEHSPKQDARGEVVMASSV--HDRLACDPNTK----FAAPAHGKHWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVG-SNTNETITMPHAGVEDIVAIMIPEPKGKELVSLLERNVTVTMYITIGTRNLQKY--VSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQVRTIRKGDKETESDFDNCAVCIEGYKPSDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPIDFEGSLGGPPTNQITGASDTTVNESSVTLDPAVRTVGALQVVQDPDPAPQEGEAIFTTNSDQ-EPAVSSDSDISLIMALEVGLSDVELSTDQDCEEVKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DTZ6-1", "uniprot_id": "RN150_MOUSE", "id": "Q5DTZ6-1", "name": "RING finger protein 150", "aln": "--MTMSLIQACRSLALS--TWLLSFCFVHLLCLDFTVAEK------------------------EEWYTAFVNITYLE--PEPGAAVAGSGGGAELHTEKSECGRYGEHSPKQDARGEVVMASSA--QDRLACDPNTK----FAAPAHGKHWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVG-SNTNETITMPHAGVEDIVAIMIPEPKGKEIVSLLERNITVTMYITIGTRNLQKY--VSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQVRTIRKGDKETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPIDFEGSLGGPPTNQITGASDTTVNESSVTLDPAVRTVGALQVVQDPDPAPQEGEAIFTTNSGQ-EPALSSDSDISLIMALEVGLSDVELSTDQDCEEVKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULK6-1", "uniprot_id": "RN150_HUMAN", "id": "Q9ULK6-1", "name": "RING finger protein 150", "aln": "--MAMSLIQACCSLALS--TWLLSFCFVHLLCLDFTVAEK------------------------EEWYTAFVNITYAEPAPDPGAGAAG-GGGAELHTEKTECGRYGEHSPKQDARGEVVMASSA--HDRLACDPNTK----FAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVG-SNTNETITMPHAGVEDIVAIMIPEPKGKEIVSLLERNITVTMYITIGTRNLQKY--VSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGPPTNQITGASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQ-EPAVSSDSDISLIMAMEVGLSDVELSTDQDCEEVKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B8A6H5-1", "uniprot_id": "B8A6H5_DANRE", "id": "B8A6H5-1", "name": "", "aln": "--MVVSLTQACRSLALS--TWLLSFCFVHLLCLDFTVAEK------------------------EEWYTAFVNITYLD------------PVTSEIKTDRSECGRYGEHSPKRDARGFVFMP-----QDRQACDGNTR----FPLPHPSIPWIALIAKGNCTFREKIRHAAALNASAVVIFNVGSSNSNDTITMPHHGTGDVVAIMIPEPKGREIMALLEKNITVAMHISIGTRNLQKY--VSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRSQRRLGDAAKKAISKLQVRTIRKGDKETDSDFDNCAVCIEDYKPNDVVRILPCRHVFHRNCVDPWLQDHRTCPMCKMNILKALGIPPNTDCSDDAPPDYETSSG-QPSIAVTGASEVSVGESSLVLDQPLRITGLSHDYQEMNSVPADAESPHIASSEQHQPSMSNDPD---IMPMEI----AELQSDLEQEDVKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q566M8-1", "uniprot_id": "RN150_DANRE", "id": "Q566M8-1", "name": "RING finger protein 150", "aln": "--MALSVIQACRSLALS--TWLLSFCFVHLLCLDFTVAEK------------------------EEWYTAFVNITYVD------------PDTAEVRTEKTECGRYGEHSLKREARGVLAMPAAP--HDRHACDPSGR----FTPRAHG-AWIALISRGNCTYKDKIRHAVGHNASAVVIFNVGSSNPNETITMPHQGISDVVAIMIPEPKGRELVLLMERNITVHMHITIGTRNLQKY--VSRTSVVFVSISFIILMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISQLQVRTIRKGDQETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKCCVDPWLVDHRTCPMCKMNILKALGLTSSAECLNELPLDYELAVGGVALNAMVMSDDVMAGDVGGARDPGVRMGGLPQVLLDSEPLSQDT---MPTEQSELQPIASGSSD----VSLTTGAGHSDIDTPTD--DPKC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06003-1", "uniprot_id": "GOLI_DROME", "id": "Q06003-1", "name": "E3 ubiquitin-protein ligase goliath", "aln": "MYIRKTLLLACLVLLFGGLPPLTFPATTTTLVAAMSIANQDLERYFRPGNGTHSFSGMEDRIAVDVYNYAFLNWSYVEH-----------GNMLCNMEFAQEQARYGEGKVLNVTGRLIHITATDNFSDDYACTPYIRGTLGAPIPDKGETWIALVRRGRCTFEEKVKHVYQQNAAGVIIYNDKQVMQLEKMQIKGK-TRNIAAVITYQNIGQDLSLTLDKGYNVTISIIEGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGKFSD-EKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDVLKFYGYVFLGSEESILEYQPDPPQGLALVEARDESADLNRSRDFVVDFPRVFVLDSGCVVGAREMLFPCRIPERSQSSLSLRQARDWVSLMSNKLEEQQGLRSMRNDEMQQVIK---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: ** * :. . * . . * :::*:: : : **:* :* : * .**** . . : : :. * ** : . . ****: :*.**:.:*:::. **:.*:*:* :.: : ::.*:: : *::: :::. .* : * * *.::. :.****:*******:******.**:********* :*:*:..*.* ..:**** :: :* : .* *.: * * **:*** ***.*.:*****:* **: *:**** :********:::** * . . : : . * : : . . : . : .. . . . . : . : . ", "identical_positions": 112, "similar_positions": 120, "identity": "23.48%" }, { "cls_id": "homologset.agr.MGI:2443862", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LXS7-1", "uniprot_id": "LYSET_RAT", "id": "F1LXS7-1", "name": "Lysosomal enzyme trafficking factor", "aln": "MPKAPDYSELSDSCTLAGGTARFSGPLHRAWRMMNFRQRMGWIGVGLYLLASAAAFYYVFEINETYNRLALEHIQQHP-----------EEPREGTTWTHSLKARLLSLPFWLWTVIFLIPYLQMFLFLYSCTRADPKTVGYCIIPICLAIICNRHQAFVKASNQISRLQLIDT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH26-1", "uniprot_id": "LYSET_MOUSE", "id": "Q8BH26-1", "name": "Lysosomal enzyme trafficking factor", "aln": "MPKAPDCSELSDSCSLAGGTGRFSGPLHRAWRMMNFRQRMGWIGVGLYLLASAAAFYYVFEINETYNRLALEHILQHP-----------EEPREGTTWTHSLKARLLSLPFWLWTIIFLIPYLQMFLFLYSCTRADPKTVGYCIIPICLAVICNRHQAFVKASNQISRLQLIDT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6I4-1", "uniprot_id": "LYSET_HUMAN", "id": "Q8N6I4-1", "name": "Lysosomal enzyme trafficking factor", "aln": "MPKPPDYSELSDSLTLAVGTGRFSGPLHRAWRMMNFRQRMGWIGVGLYLLASAAAFYYVFEISETYNRLALEHIQQHP-----------EEPLEGTTWTHSLKAQLLSLPFWVWTVIFLVPYLQMFLFLYSCTRADPKTVGYCIIPICLAVICNRHQAFVKASNQISRLQLIDT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5TZA3-1", "uniprot_id": "LYSET_DANRE", "id": "Q5TZA3-1", "name": "Lysosomal enzyme trafficking factor", "aln": "--------------------------------MMNFRQRMGWIGVGLYLLASVAAVYYIFEISQTYNRLALAQVEKTSGAQAKWPGDASSSSPSSTSWIVTLKTRLLLLPFWVWATIFLLPYLQVFLFLYSCTRADPKTVGYCILPICLAVLCNRHQTFTKASNQISRLQLIDT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ********************.**.**:***.:******* :: : . ... ..*:* :**::** ****:*: ***:****:*******************:*****::*****:*.**************", "identical_positions": 96, "similar_positions": 27, "identity": "55.17%" }, { "cls_id": "homologset.agr.MGI:2443864", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UY01-1", "uniprot_id": "LRC31_HUMAN", "id": "Q6UY01-1", "name": "Leucine-rich repeat-containing protein 31", "aln": "----------------------MSQTRKKTSSEGETKPQTSTVNKFLRGSNAESRKEDNDLKTSDSQPSDWIQKTATSETAKPLSSEMEWRSSMEKNEHFLQKLGKKAVNKCLDLNNCGLTTADMKEMVALLPFLPDLEELDISWNGFVGGTLLSITQQMHLVSKLKILRLGSCRLTTDDVQALGEAFEMIPELEELNLSWNSKVG-GNLPLILQKFQKGSKIQMIELVDCSLTSEDGTFLGQLLPMLQSLEVLDLSINRDIVGSLNSIAQGLKSTSNLKVLKLHSCGLSQKSVKILDAAFRYLGELRKLDLSCNKDLGGGFEDSPAQLVMLKHLQVLDLHQCSLTADDVMSLTQVIPLLSNLQELDLSANKKMGSSSENLLSRLRFLPALKSLVINNCALESETFTALAEASVHLSALEVFNLSWNKCVGGNLKLLLETLKLSMSLQVLRLSSCSLVTEDVALLASVIQTGHLAKLQKLDLSYNDSICDAGWTMFCQNVRFLKELIELDISLRPSNFRDCGQWFRHLLYAVTKLPQITEIGMKRWILPASQEEELECFDQDKKRSIHFDHGGFQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6VYM1-1", "uniprot_id": "F6VYM1_MOUSE", "id": "F6VYM1-1", "name": "", "aln": "----------------------MACIELPKVKPGRDKPG-----------------------------------------VMPLDLEMDLKSNMEDSDWFLRKLCGRAADTGLDLNSYGLTAVDVKET--------DLEELDVSWNDFARGALHMLTQQMHPVNKLKVLRLSSCRLTTEDVQTLGGALEMTPELEELSLSWNSQVG-GKLPRVLHTFQQGSKIRTLELVDCALTSQDGVFVGHLLPKLQSLQVFDLSNNRNIGSCLEVIAQGLRSASGLKELKLRSCGLSQKSIRLLDGVFASLDVLRILDLSCNKELGGGFEDVPAQLASLKHLEVLDLHQCSLTAGDVTSLTQIIPLLSNLEELDLSSNRDVGGSSENLLCRLRFLPALKSLLINSCALQSEAFAALADASVYLPALEILNLSWNKCVGGNLELLQQTLHLSRLLRVLRLSSCSLVTEDVVLLASVIQSGHLATLQKLDLSYNDGICDAGWAILCQNLCFLKELTELDISLRPSSSQDCGQWFSHLLCAVTQLPVITEIEMRRWVIPALQERELDCFTQDHQREIRFDHGGFQRAAL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3APA9-1", "uniprot_id": "A0A8M3APA9_DANRE", "id": "A0A8M3APA9-1", "name": "", "aln": "MDSSVAARGKESVQKRSPLDLIMNQLRRKTSFTERKKTSVG---RLFRPSESSDRKNGGTPEIKESDLSEGKENKEPERESSITAEESGSVVGWGRVKQFMQKLGKTPHSHNLSLSHCDLTATDLVELATLLPFMSELELMELSWNDLLGGSLKALTAHLQHVEKLRMLKLCSCRLAPQDLTALGEALDCIPLIEVLDLSWNVGIGAGNFRHFTEQIQPENRLKDLRLVDCQLSETDITALSEALPLLSGLEELDLSNNKLSIKGMENLTSSFSATPRLKTLKLSMCGLGKDHLSALGQAFRFITALEHMDLSCNKEAGGGLSTLAANLLLLTHLRSLDMHLCCLTKDDVLTLVQVAPSLKELRELDLSSNKSVGDTLQNLLQSLP-LSQMNKLPLNNCDLSDSACQALATVMQTLKRLESLNLSWNKCVGENLREFLEPLQADCKLQELRLSSCNLTTEDVLHLESACQRGALSQLKLLDLSYNGSVGDGGWTSLFGKAASLKGLEELDVSLRPSASLSVSPWLPALLEALPQLTSLSRLSLQHWTLSSAERDKLEKILSKKSAILECDRLNTPTPKAAG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . . *. * . . *::** . . *.*. .**:.*: * :** :::***.: *:* :* ::: *.**::*:* ****:.:*: :** *:: * :* *.**** :* *:: . . :* .::: :.**** *:. * . :.. ** *..*: :*** *: :: ::..: ::. ** *** ***.:. : *. .* : *. :******: ***:. .*:* *.**. **:* *.** .** :*.*: * *.:*.*****:*:.:*.: :*** * *. ::.* :*.* *...: *** . * ** :********* **. : :.*: . *: ******.*.**** * *. * * *: *: ******..: *.**: : : ** * ***:***** . . *: ** *:.:*. ::.: :::* :.: :. :*: : ..:. :. *: . ", "identical_positions": 175, "similar_positions": 167, "identity": "30.12%" }, { "cls_id": "homologset.agr.MGI:2443868", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMG4-1", "uniprot_id": "D3ZMG4_RAT", "id": "D3ZMG4-1", "name": "Lipase member H", "aln": "---MRIYTFLCWICWVRFGYLNFPSKSNGGSKNPENNRTCLEFSKSNAMN----SLKDLFYPTVKINLLMYSRNNAKCAEPLFESNNSVNARFNPSKKTIWIIHGYRPLGSTPMWIHKFTKAFLKQEDVNLIVVDWNQGATTFIYGRAVKNTRKVAEILREYIENLL-IHGASLDNFHFIGMSLGAHICGFVGKLFQGQLGRITGLDPAGPKFSGKPSNCRLDYTDAKFVDVIHSDSQGFGILEPSGHIDFYPNGGRNQPGCPTSLLSGMDYIKCDHQRAVHLFLEAFETNCNFVSFPCRSYRDYKSGLCVGCGNLYKDSCPRLGIQANLWKEELKKKTEEWPLRTTAFLDTSSQNPFCTYYFALNIVALNETMKNGSLSFGLLKDLGVLEYPRLYVKTMPFANLQEVKILAQFVNDIVNISRISMTYYQSTSPFCPTCEYRIKSLVFKS----LTHPERPPICKYDFVLKERARIDLQPDECKKQTG------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F6YQT7-1", "uniprot_id": "F6YQT7_MOUSE", "id": "F6YQT7-1", "name": "Lipase member H", "aln": "---MRIYIFLCLICWARFGYLNFQSNTTGVSKDPEKKRTCLEFTKLSAMN----SLKDLFCPKVKINLLMYSRGNAKCAEPLFESNNSLNTRFNPAKKTVWIIHGYRPFGSTPVWLSRFTKAFLKQEDVNLIVVDWNQGATTFMYSRAVRNTRRVAEILRETIENLL-IHGASLDNFHFIGMSLGAHISGFVGKIFHGQLGRITGLDPAGPQFSRKPSNSRLYYTDAKFVDVIHTDIKSLGIGEPSGHIDFYPNGGKHQPGCPTSIFSGTNFIKCDHQRAIYLFLAAFETSCNFVSFPCRSYKDYKNGLCVDCGNLYKDSCPRLGNQAKLWKEELKKKTEEWPLRTTAFLDTSSQNPFCTYYFALNIVALSETMRNGSISFGLLNDLGDLEYSTLYEKSKPFDNLQEVKILVQFVNDIVSISRICLTYFQSTNPYCAACQYKIQSLVLKS----LTYPERPPICKYNFVLKEGTRVDLQPDECNTQME------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XZB0-1", "uniprot_id": "LIPI_HUMAN", "id": "Q6XZB0-1", "name": "Lipase member I", "aln": "---MRVYIFLCLMCWVRS----------------DNKRPCLEFSQLSVKD----SFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLL-KHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNISSIGLTYFQSSNLQCSTCTYKIQSLMLKS----LTYPERPPLCRYNIVLKDREEVFLNPNTCTPKNT------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DBU8-1", "uniprot_id": "LIPH_DANRE", "id": "Q6DBU8-1", "name": "Lipase member H", "aln": "MIYRKIIWGILYVTLMLFDT--------------HRAQECEEMTDLNFKD----SLAG---TSLKVRLLLYTRADPSCGQLLSHQEPFSNSQFNVSSVTTFLIHGYRPTGSPPVWMKQFVEFLLNRRDMNVIVVDWNRGATNMNYWQVVKNTRKVANNLTDLIQKMK-DNGANLSSIHMIGVSLGAHISGFTGANFNGEIGRITALDPAGPEFNGRPPEDRLDPSDALFVEALHTDMDALGYRNLLGHIDYYANGGADQPGCPKTILSGSEYFKCDHQRSVFLYMSSVNGSCPIIAYPCESYTDFQDGTCMDCGKFKSAGCPIFGYDSVRWRDTLVQLE-----QTRTYFQTNKASPFCKVGYKVDIVSWNQKTHWGYLTIKLSNGT-EETQVELNHKSLKFERFQETSVLAQFERDIQPVKKITLKFCPR-KGLRPRKKLRLLHIRLTP----LQNHLR-PLCRYDLLLEESKDVTFKPIPCEDSNF------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9PG68-1", "uniprot_id": "A0A8M9PG68_DANRE", "id": "A0A8M9PG68-1", "name": "", "aln": "---MSPWRFLILLSIFLLCK--------------GEDNDCDNFTDLDFHE----SFIG---TNLYVRLLLYTRANLECGQELPHHNFTQQPLFNVTRPTTFVIHGYRPTGAPPIWINHIVHLLAAQKDMNILVVDWNRGAANLNYLTAVANTRGTALNITRFIESME-KEGASLDSIHLIGVSLGAHVAGFIGAMLGGRVGRITGLDPAGPMFASVSPEERLDPTDAQFVDVLHTDMNSFGLRGTHGHIDFYANGGLDQPGCPKTIFSGKSYFVCDHQRSVFLYLCSLNRTCSLTGYPCSSYSDFLSGQCLQCETFKPASCPVLGYDLSQWRDTLLRLG-----QTRAYFSTTAELPYSKTSYRVDLVTWNQFLRWGVVILRLHNGK-NVTEAHIDNKLMRFEQYTSTRLLAQFDEDLYPIQKISLRIVTG-NVIGPRYKIRLLRIRISP----LEKPYRSLMCRYDIIVEENAEVSFKPLPCH----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P02843-1", "uniprot_id": "VIT1_DROME", "id": "P02843-1", "name": "Vitellogenin-1", "aln": "---MNPMRVLSLL-------------------------ACLAVAALAKP---------------------NGRMDNSVNQALKPSQWLSGSQLEAIPALDDFTIERLENMNLERGAELLQQVYHLSQIHHNVEPNYVP--SGIQVYVPKPNGDKTVAPLNEMIQRLKQKQNFGEDEVTIIVTGLPQTSETVKKATRKLVQAYMQRYNLQQQRQHGKNGNQDYQDQSNEQRKNQRTSSEED--YSEEVKNAKTQSGDIIVIDLGSKLNTYERYAMLDIEKTGAKIGKWIVQMVNELDMPFDTIHLIGQNVGAHVAGAAAQEFTRLTGHKLRRVTGLDPSKIVAKSKNTLTGLARGDAEFVDAIHTSVYGMGTPIRSGDVDFYPNGPAAGVPGASNVVEAAMRATRYFAESVRPGNERSFPAVPANSLQQYKQNDGFGKRAYMGIDTAHDLEGDYILQVNPKSPFGRNAPAQKQSSYHGVHQAWNTNQDSKDYQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02844-1", "uniprot_id": "VIT2_DROME", "id": "P02844-1", "name": "Vitellogenin-2", "aln": "---MNPLRTLCVM-------------------------ACLLAVAMGNPQSGNR----------------SGRRSNSLDNVEQPSNWVNPREVEELPNLKEVTLKKLQEMSLEEGATLLDKLYHLSQFNHVFKPDYTPEPSQIRGYIVGERGQKIEFNLNTLVEKVKRQQKFGDDEVTIFIQGLPETNTQVQKATRKLVQAYQQRYNLQPYETTDYSNEEQSQRSSSEEQQTQRRKQNG--------EQDDTKTGDLIVIQLGNAIEDFEQYATLNIERLGEIIGNRLVELTNTVNVPQEIIHLIGSGPAAHVAGVAGRQFTRQTGHKLRRITALDPTKIYGKPEERLTGLARGDADFVDAIHTSAYGMGTSQRLANVDFFPNGPSTGVPGADNVVEATMRATRYFAESVRPGNERNFPSVAASSYQEYKQNKGYGKRGYMGIATDFDLQGDYILQVNSKSPFGRSTPAQKQTGYHQVHQPWRQSSSNQGSRRQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06607-1", "uniprot_id": "VIT3_DROME", "id": "P06607-1", "name": "Vitellogenin-3", "aln": "---MMSLRICLLA-------------------------TCLLVAAHASK--------------------------DASNDRLKPTKWLTATELENVPSLNDITWERLENQPLEQGAKVIEKIYHVGQIKHDLTPSFVPSPSNVPVWIIKSNGQKVECKLNNYVETAKAQPGFGEDEVTIVLTGLPKTSPAQQKAMRRLIQAYVQKYNLQQLQKNAQEQQQQLKSSDYDYTSSEEAADQW--------KSAKAASGDLIIIDLGSTLTNFKRYAMLDVLNTGAMIGQTLIDLTNKG-VPQEIIHLIGQGISAHVAGAAGNKYTAQTGHKLRRITGLDPAKVLSKRPQILGGLSRGDADFVDAIHTSTFAMGTPIRCGDVDFYPNGPSTGVPGSENVIEAVARATRYFAESVRPGSERNFPAVPANSLKQYKEQDGFGKRAYMGLQIDYDLRGDYILEVNAKSPFGQRSPAHKQAAYHGMHHAQN-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : .: . : . . : . .: : . . : :: . ... :. .* . : . . . . . .*. . : : : . . * . . . * : : . . : . : ..: : . : * : : : :: .: ", "identical_positions": 6, "similar_positions": 63, "identity": "1.21%" }, { "cls_id": "homologset.agr.MGI:2443872", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BYL1-1", "uniprot_id": "SAM10_HUMAN", "id": "Q9BYL1-1", "name": "Sterile alpha motif domain-containing protein 10", "aln": "----------------------------------------------------------------------------MFTELRSKLSPPRGR---------AGAV---------RAGFG------------------------------------ERRDVDATAHFS-----------------FCRTLLEHTVSAESIPCHLPRTPGTSLTWHDSRSQRAASSRPIKLLQQPGTDTPQGRLYSDHYGLYHTSPSLGGLTRPVVLWSQQDVCKWLKKHCPHNYLVYVEAFSQHAITGRALLRLNAEKLQRMGLAQEAQRQEVLQQVLRLQVREEGRSLQLLSQASFGKMS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TST3-1", "uniprot_id": "SAM10_MOUSE", "id": "Q7TST3-1", "name": "Sterile alpha motif domain-containing protein 10", "aln": "----------------------------------------------------------------------------MFTELRSKLSPPRAR---------AGAV---------RPGFG------------------------------------ERPDVDASAHFS-----------------FCQTLLEHTVSAENIPCHLPRTPGTSLTWHDSRSQRASSSRPIKLLQQPGSEIPQARLYSDHYGLYHTSPSLGGLTRPVVLWSQQDVCKWLKKHCPHNYLVYVEAFSQHAITGRALLRLNADKLQRMGLTQEAQRQEVLQQVLHLQVREEGRSLKLLSQASFGNMS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M2I9-1", "uniprot_id": "F1M2I9_RAT", "id": "F1M2I9-1", "name": "", "aln": "KRNEQIRIHRYLGENDPDLGQTEQVKAHRCDYPHHHQTEGTSLANCKGRPAGCKRGWSTESYPGAQGRLLLWRTSSAYAARRAADTPPSSRSAPCAQGWAAGALPRRLPGRGDRLGLGRLRRVGTRCALPTGHSGCLVLREGRVPEPRIRGLHVHRAAVKAEPPASSRRGCAYRLRGAPGCGRFCQTLLEHTVSAENIPCHLPRTPGTSLTWHDSRSQRASSSRPIKLLQQPGSETPQARLYSDHYGLYHTSPSLGGLTRPVVLWSQQDVCKWLKKHCPHNYLVYVEAFSQHAITGRALLRLNADKLQRMGLTQEAQRQEVLQQVLHLQVREEGRSLQLLSQASFGNMS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1QVC1-1", "uniprot_id": "A0A8M1QVC1_DANRE", "id": "A0A8M1QVC1-1", "name": "", "aln": "------------------------------------------------------------MQQTANSLIKIFALGGVVQEHQLLLLPERTG-HPWAWQTPTEAIT-------ERYAFIP------------------------------------TMAVDAASSFS-----------------FCRAALEHTISAEELNYQLPRRAGGNLTWHEGHEQRVTR-RTVKLLQQPGTEGIQIQP-GEAFTVYHTSPTLSSLCKPVVLWTQQDVCKWLKKHCPHNYLTYVEAFSHHAITGRALLRLNGEKLARMGIIQETLRQEVLQQVLQLQVREEVRNLQLLSRASFGNIS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8ML92-1", "uniprot_id": "AVE_DROME", "id": "Q8ML92-1", "name": "Protein aveugle", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGEETINSTQNKTR-----------------------------------------------TKTTRPKAVYLWTVSDVLKWYRRHCG-EYTQYEQLFAQHDITGRALLRITDSSLQRMGVTDNRDREAIWREIVKQRLKTDIMEIRDMERLNIY---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * : : : :.* **: .** ** ::** :* * : *::* ********:. ..* ***: :: *: : ::::: ::: : .:: :.: .: ", "identical_positions": 27, "similar_positions": 41, "identity": "7.74%" }, { "cls_id": "homologset.agr.MGI:2443876", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDP9-1", "uniprot_id": "D3ZDP9_RAT", "id": "D3ZDP9-1", "name": "Zinc finger and BTB domain-containing protein 11", "aln": "MSSEESYRAILRYLTNEREPYAPGTEGNVKRKIRKAAACYVVRGGTLYYQRRQRHRKTFAELEVVLQPERRQGLIEAAHLGPGGTHHTRHQTWHDLSKTYWWRGILKQVKDYIKQCSKCQEKLDRSRPISDAS--EMLEELGLDLESGEESNESEDDLSNFTSPPTTASKTSKKKPVSKHELVFVDTKGVVKRSSPKHCQAVLKQLNEQRLSNQFCDVTLLIEGEEYKAHKSVLSANSEYFRDLFIEKGAVSSHEAVVDLSGFCKASFLPLLEFAYTSVLSFDFCSMADVAVLARHLFMSEVLEICESVHKLMEEKQLTVYKKGEVQTVA-----STQDLAAHNGAATPPGPRNEATTT-------LSSDLGHCEIVLLVNGEVPETE---------QNGEPGQQPAPQVSAEAEASVSP------------------AGCIPNPPTEMGAASLATESNQPELESAVV-REDGGVASVPPKISEENVINTSQEDSDIGNDTSPEDTCTKDFSD------------HSQSSGQPLKDEETLIEATEKTDSGQDDD----TYRSRLRQRSVNEGGYIRLHKGMEKKLQKRKAISKSAVQQVAQKLVQRGKKMKQPKRD--------------------AKES----------------------AEETPHKCGECGMVFPRRYAFIMHTLKHERARDYKCPLCKKQFQYSASLRAHLIRHTRKDAPTSSSSNSTSNEASGASSEKG--RTKREFICSICGRTLPKLYSLRIHMLKHTGVKPHACQVCGKTFIYKHGLKLHQSLHQSQKQFQCELCVKSFVTKRSLQEHMSIHTGESKYFCSVCGKSFHRGSGLSKHLKKHQPKPEVRGYHCTQCEKSFFEARDLRQHMNKHLGVKPFQCQFCDKCYSWKKDWYSHVKSHSVTEPYRCNICGKEFYEKALFRRHVKKATHGKKGRAKQNLERVCDQCGRKFTQLREYRRHMNNHEGVKPFECLTCGVAWADARSLKRHVRTHTGERPYVCPVCSEAYIDARTLRKHMTKFHRDYVPCKIMLEKDTLQFHNQGTQVEHAVSILTADMQ-EQESSGPQELETVVVTGETMEVLEAVAATEECPSVSTLSDQSIMQVVNYVLAQQQGQKLSEVAEAIQTVEVEVAHMPEAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G5E8B9-1", "uniprot_id": "ZBT11_MOUSE", "id": "G5E8B9-1", "name": "Zinc finger and BTB domain-containing protein 11", "aln": "MSSEESYRAILRYLTNEREPYAPGTEGNVKRKIRKAAACYVVRGGTLYYQRRQRHRKTFAELEVVLQPERRQGLIEAAHLGPGGTHHTRHQTWHDLSKTYWWRGILKQVKDYIKQCSKCQEKLDRSRPISDAS--EMLEELGLDLDSGEESNESEDDLSNFTSPPSTASKSSKKKPVSKHELVFVDTKGVVKRSSPKHCQAVLKQLNEQRLSNQFCDVTLLIEGEEYKAHKSVLSANSEYFRDLFIEKGAVSSHEAVVDLSGFCKASFLPLLEFAYTSVLSFDFCSMADVAVLARHLFMSEVLEICESVHKLMEEKQLTVYKKGEVQTVA-----STQDLAAHNGTTTPPGTRNEATTT-------LSGELGHCEIVLLVNGELPEAE---------QNGEPEQQPAPQASPEAEASVSP------------------VEGIPEPHPEMGTASLAKESNQP--ESAVT-REDGIVASVHPKISKENVTNASQEDSDTGNDTSPEDIGAKDCPD------------HSQSPGQPSKDEDTLTEATEKTDSGPDDD----TYRSRLRQRSVNEGGYIRLHKGMEKKLQKRKAISKSAVQQVAQKLVQRGKKMKQPKRD--------------------AKES----------------------TEETAHKCGECGMVFPRRYAFIMHTLKHERARDYKCPLCKKQFQYSASLRAHLIRHTRKEAPTSSSSNSTSTEASGGSSEKG--RTKREFICSICGRTLPKLYSLRIHMLKHTGVKPHACQVCGKTFIYKHGLKLHQSLHQSQKQFQCELCVKSFVTKRSLQEHMSIHTGESKYFCSICGKSFHRGSGLSKHLKKHQPKPEVRGYHCTQCEKSFFEARDLRQHMNKHLGVKPFQCQFCDKCYSWKKDWYSHVKSHSVTEPYRCNICGKEFYEKALFRRHVKKATHGKKGRAKQNLERVCDQCGRKFTQLREYRRHMNNHEGVKPFECLTCGVAWADARSLKRHVRTHTGERPYVCPVCSEAYIDARTLRKHMTKFHRDYVPCKIMLEKDTLQFHNQGTQVEHAVSILTADMQ-EQESSGPQELETVVVTGETMEVLEAVAATEECPSVSTLSDQSIMQVVNYVLAQQQGQKLSEVAEAIQTVEVEVAHMPEAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95625-1", "uniprot_id": "ZBT11_HUMAN", "id": "O95625-1", "name": "Zinc finger and BTB domain-containing protein 11", "aln": "MSSEESYRAILRYLTNEREPYAPGTEGNVKRKIRKAAACYVVRGGTLYYQRRQRHRKTFAELEVVLQPERRRDLIEAAHLGPGGTHHTRHQTWHYLSKTYWWRGILKQVKDYIKQCSKCQEKLDRSRPISDVS--EMLEELGLDLESGEESNESEDDLSNFTSSPTTASKPAKKKPVSKHELVFVDTKGVVKRSSPKHCQAVLKQLNEQRLSNQFCDVTLLIEGEEYKAHKSVLSANSEYFRDLFIEKGAVSSHEAVVDLSGFCKASFLPLLEFAYTSVLSFDFCSMADVAILARHLFMSEVLEICESVHKLMEEKQLTVYKKGEVQTVA-----STQDLRVQNGGTAPPVASSEGTTTS------LPTELGDCEIVLLVNGELPEAE---------QNGEVGRQPEPQVSSEAESALSS------------------VGCIADSHPEMESVDLITKNNQTELETSNN-RENNTVSNIHPKLSKENVISSSPEDSGMGNDISAEDICAEDIPK------------HRQKVDQPLKDQENLVASTAKTDFGPDDD----TYRSRLRQRSVNEGAYIRLHKGMEKKLQKRKAVPKSAVQQVAQKLVQRGKKMKQPKRD--------------------AKEN----------------------TEEASHKCGECGMVFQRRYALIMHKLKHERARDYKCPLCKKQFQYSASLRAHLIRHTRKDAPSSSSSNSTSNEASGTSSEKG--RTKREFICSICGRTLPKLYSLRIHMLKHTGVKPHACQVCGKTFIYKHGLKLHQSLHQSQKQFQCELCVKSFVTKRSLQEHMSIHTGESKYLCSVCGKSFHRGSGLSKHFKKHQPKPEVRGYHCTQCEKSFFEARDLRQHMNKHLGVKPFQCQFCDKCYSWKKDWYSHVKSHSVTEPYRCNICGKEFYEKALFRRHVKKATHGKKGRAKQNLERVCEKCGRKFTQLREYRRHMNNHEGVKPFECLTCGVAWADARSLKRHVRTHTGERPYVCPVCSEAYIDARTLRKHMTKFHRDYVPCKIMLEKDTLQFHNQGTQVAHAVSILTAGMQ-EQESSGPQELETVVVTGETMEALEAVAATEEYPSVSTLSDQSIMQVVNYVLAQQQGQKLSEVAEAIQTVKVEVAHISGGE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RAC1-1", "uniprot_id": "F1RAC1_DANRE", "id": "F1RAC1-1", "name": "", "aln": "MSSEESYLAIQRYLTDEREPYAPGTHGNTKRKIRKAAACYIVRNGILYYQRRQKGLDEFTELEVVLTADRRKELITEAHITSGGEHLNQQQTWEIISQKYWWRGVLKQVKDCIKECIHCQTKQEKGRNNTEDAPKQTARQVRQKISSACASEEEDDEIH-------EDLEEEQSTTVDKHELVFVDSKGIVKQFLQKHGQTMLDKLNLQRMNNEFCDITLIIEGEEYRAHKAVLASCSDYFYELFVEKGAVSSHEAVVDLSGFSKASFLPLLDFAYTSNLTFNFCVMAEVATLARHLLMAEVLQICESVHKKVEEQKLMVYQRGDIHTVLPNQPASTQPITPTAAETYVVTMQSDGTAEAGQSLAVITSEIGTAESLALLAGATVDGETMTVVTHSGQAGSAESLAMVAHSGQAEEGETMTLVTHSGQAGSGESLAVVQACWSVEEPQVGDTPVVQSMQTGAFLISVDPGKTGASEIVHLAAAAPPAVQDEPQASKPIHQTEPPAAAPQPSPAPLKRRPGRPPKVKQQEPPPPLPSEDEPMEMEGVEDDEKQEDECIDPNKRYLRKRSVREGGYVRLHMGLETEEEEK--ITSPPAKIPQKGLAKRGRPVQSAKKNPETEFSETNLEAAPNAIVTSAKEPEPVIVEQPETVEEGALPGDPEGAVEGEHACNECGMVFQRRYTLIMHALKHEKARIFKCSICNKEFQYAASLRAHLARHKHQKSQRASLTRAMATEDSQGSDDQARFRTRREFVCDICGKTMPKLYSLRIHMLNHTGVRPHSCKVCGKSFATKHSLKMHRALHDSLKRFHCTVCEKSFVTKRSLEEHTSIHTGESKYLCTTCGASFHRASGLSKHLKKHQPKPEVRSFHCSHCDKSFFEAKDLQQHMNKHLGLKPFQCQVCGKCYSWKKDWYSHVKSHSVAEPFRCNVCGKEFFEKALFRRHVKKATHGKKGRVKQNLERECEHCGRKFTQLREYRRHMNNHQGVKPFECLTCGVAWADARSLKRHVRTHTGERPYVCPLCQEAHIDARTLRKHITKFHGDQLPGKIMLEKDTLQFHNQGTQVEHAVSILSSELPPELQPPQPPATEEIETVLITEETVEAVQAMNDGAAVTTLSDQSIMQVVNYVLAQQAAVKVEEAPEIIQTMEVEVAHVAEVE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* ** ****:*********.**.***********:**.* *******: . *:****** .:**: ** **: .** * .::***. :*:.*****:****** **:* :** * ::.* :: : : .:: .:.*. *:*.:*:: : :...*.********:**:**: ** *::*.:** **:.*:***:**:******:***:**:: *:** :**:*****************.********:***** *:*:** **:** *****:*:***:******* :**::* **::*:::** *** : . : .:.*: :. ::* .* : *: * : * * *. . * :** . : . .:: . : . : : : . : : . . . : * :: .. .: . : *. * .:: * ::* . : **:***.**.*:*** *:*.: ::: :.....: : *.:**: ::..*:: *** : * * *.****** ***::*** ****:** :**.:*:*:***:******* **.::.: :* :.: :.* * *.::. **:***:*.***:*:***********:****:**:*:****:* **.**:*::**:* *:*:* :* *********:** *********:*: ** ****.******:**********.:**::*:******:**:********:******.*.******************:**:***:*****:*******************.****** *::******************:************************************:*.**:*********:**** * :* ****************** ******:: : * :.. * * : .. * *.:*** * :: .:*:****************** . *:.*..* ***::*****:. *", "identical_positions": 576, "similar_positions": 260, "identity": "49.87%" }, { "cls_id": "homologset.agr.MGI:2443878", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTY2-1", "uniprot_id": "S4A7_MOUSE", "id": "Q8BTY2-1", "name": "Sodium bicarbonate cotransporter 3", "aln": "-----MEADGAGEQMRPLLTRGPDEEAVVDLGKTSSTVNTKFEKEELESHRA--VYVGVHVPFSK---ESRRRHKHRG-----------------HKHHHRRRKDKDSDKEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDDSIRENVREALLKRHHHQNEKRFTSRIPLVRSFADIG--------------------------------------------------------------------------------------------------------------------------------------------------ILASPQSAPGNLDNSKSGEMKGNGSGGSRENSTVDFSK---------------------VDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLSGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFPNGSAAMSVGPPKEDDHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCRDYHLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFHLGEIYAFNMHNNLDELTSYTCVCAEPSNPSNETLELWKRKNITAYSVSWGNLTVSECKTFHGMFVGSACGPHGPYVPDVLFWCVVLFFTTFFLSSFLKQFKTKGYFPTKVRSTISDFAVFLTIVIMVAIDYLVG----IPSPKLHVPEKFEPTDPSRGWIISPLGD--NPWWTLLIAAVPALLCTILIFMDQQITAVIINRKEHKLK--------------------------------------------------------------------------------------FIPMPVLYGVFLYMGVSSLKGIQFFDRIKLFGMPAKHQPDLIYLRYVPLWKVHVFTVVQLTCLVLLWVIK-ASAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQDD--------------EDTVHLPFER------GSLLQIPVKTLKYSIDPSVVN--------------------ISDEMAKTAQWKALSMNTENAKVTRPNTSPEKPVSVTINFEDEPSK-KYMDAETSL------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R1N3-1", "uniprot_id": "S4A7_RAT", "id": "Q9R1N3-1", "name": "Sodium bicarbonate cotransporter 3", "aln": "-----MEADGAGEQMRPLLTRGPDEEAVVDLGKTSSTVNTKFEKEELESHRA--VYVGVHVPFSK---ESRRRHRHRG-----------------HKHHHRRRKDKDSDKEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDDSIRENVREALLKRHHHQNEKRFTSRIPLVRSFADIGKKHSDPHLLERNGEGLSASRHSLRTGLSASNLSLRGESPLSLLLSHLLPSSRAGTPAGSRCTTPVPTPQNSPPSSPSLSRLTSRSSQQTQPQAPEVLVSPDRDDIPRVVIHPPEEDIEALK-GQEQKNEENTDFTP---------GILASPQSAPGNLDSSKSGEVKGNGSGGSRENSTVDFSK---------------------VDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLSGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPAFPNGSAPVSADPPKEADHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCRDYHLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFHLGEIYAFNMHNNLDALTSYTCVCAEPSNPSNETVELWERKNVTAASISWANLTVSECKTFHGMFVGSACGPHGPYVPDVLFWCVVLFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVAIDYLVG----IPSPKLHVPEKFEPTDPSRGWIISPLGD--NPWWTLLIAAVPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMI--FILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQFFDRIKLFGMPAKHQPDLIYLRYVPLWKVHVFTVVQLTCLVLLWVIK-ASAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQGD--------------GDTVHLPFER------GSLLQIPVKTLKY--------------------------------------------------------SPEKPVSVTINFEDEPSK-KYMDAETSL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6M7-1", "uniprot_id": "S4A7_HUMAN", "id": "Q9Y6M7-1", "name": "Sodium bicarbonate cotransporter 3", "aln": "-----MERFRLEKKLP-----GPDEEAVVDLGKTSSTVNTKFEKEELESHRA--VYIGVHVPFSK---ESRRRHRHRG-----------------HKHHHRRRKDKESDKEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDESIRENVREALLKRHHHQNEKRFTSRIPLVRSFADIGKKHSDPHLLERNGEGLSASRHSLRTGLSASNLSLRGESPLSLLLGHLLPSSRAGTPAGSRCTTPVPTPQNSPPSSPSISRLTSRSSQESQRQAPELLVSPASDDIPTVVIHPPEEDLEAALKGEEQKNEENVDLTP---------GILASPQSAPGNLDNSKSGEIKGNGSGGSRENSTVDFSK---------------------VDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFHNGSTPTLGETPKEAAHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFDLGETYAFNMHNNLDKLTSYSCVCTEPPNPSNETLAQWKKDNITAHNISWRNLTVSECKKLRGVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVTIDYLVG----VPSPKLHVPEKFEPTHPERGWIISPLGD--NPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMI--FILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTVIQLTCLVLLWVIK-VSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQDD--------------DDTVHLPFEG------GSLLQIPVKALKY--------------------------------------------------------SPDKPVSVKISFEDEPRK-KYVDAETSL------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PN97-1", "uniprot_id": "A0A8M9PN97_DANRE", "id": "A0A8M9PN97-1", "name": "Anion exchange protein", "aln": "MQDFWGDVAHMRTTIGATASSGNDDEAVVDQGKTSSNIHTNFEKEELESHRA--VYVGVHVPLGR---QSRRRHRHRG-----------------HKHHRKR-KDRCSEREDGRDSPTYDTPSQRVQFILGTEDDDEEHIPHDLFTELDELCFRDGLTCEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVMLDMRANSIEEIADMVLDNMVASEQLDESVREKVRDAVLKRHHHQNEKKLSNRIPLVRSFADIGKKHSDPHLLERNGEGLSTSRLSLLRRTSSTSTPPSSRRP-SRESRYSRSSIILNQLLSSANSTPSTTPQNSPPTAHRASP-SLRPPGPSQQGPELLVARGDRDDIPEVVVFPPEEDVGDPLPAFYAVQDEKVVHDPTRLLPLPQSGLLASPQSAPGILENSKSSESRINGTGGSRENSTVDFSRDSQSPFHCSCGSLGVGTKRPAVDMNFMKKIPPGAEASNVLVGEVDFLERPIIAFIRLSPAVLLTGLTEVPVPTRFLFLLLGPFGKGAQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPTIRIEPPKSVPSQEKRKMPSMPNGSTPQS-DVIKQEAHHAGPELQRTGRIFGGLVLDLKRKAPFYWSDVRDAFSLQCLASILFLYCACMSPVITFGGLLGEATKNNISAIESLFGASLTGVAFSLFAGQPLTILGSTGPVLVFEKILFKFCSDYGLSYLPLRTSIGLWTAFLCLLLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFQLGKMYPFNMHDDLNNLTFYTCQCSPPSNTTQKMEQSWNQSGFTYDTINWTELNVQDCRDLHGEFVGPACGHNGPYIPDVLFWSVILFFTTFFLSSFLKQFKTKRYFPTKVRSSISDFAVFLTIMIMVLVDYLVG----IPSPKLHVPDRFEPTSKNRGWLISPLGD--NPTWTLFAAAIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVAVMLGVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMI--FVLMGLSVFMTSILKFIPMPVLYGVFLYMGVSSLRGIQFFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTLVQLTCLVLLWVIK-VSAAAVVFPMMVLALVFVRKLLDFCFTKRELSWLDDLMPESKKKKEDDKKKKAKEEAQRMMEA---------------EEEIEIPFDG------GDQLEIPEKTIQISTDPSVVN--------------------ISDEMAKTAAWKG-GNSSESATLLKASASEEKTACIKIRVEDEDEEDKRVDTETSL------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPI3-1", "uniprot_id": "Q8IPI3_DROME", "id": "Q8IPI3-1", "name": "Anion exchange protein", "aln": "----MAEKNEYIELPWTMNSSSGDDEAPKDPRTGGEDFTQQFTENDFEGHRAHTVYVGVHVPGGRRHSQRRRKHHHSGPGGGGGGGGGGGSIGGSGSVGGGAGKDNVSEKQQEVERP-VTPPAQRVQFILGEDVDDGTHVSHPLFSEMGMLVK-EGDEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRHQHEYAKKTRLPIIRSLADMRNHSSS------------------------------------------------------------------------------------------------------------------------KKKKSNSKHSR----------PAQNLSSITEDMVKSPSNQSMAR-PGSGTELSEQQHKG----------------------NTHFMRKIPPGAEASNILVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRP--PELPKEEVDEEEEEARLREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQG-------IYDCVCTPPIGSN-------------ASVIDYAKYNWDSCESYNGTLVGGDCG--TPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSLG----VPTQKLEVPNELKPTLSTRGWLIPPFVEK-NPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILI--FLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDLHKLDAEDNHHQHPPGSGAGANYNADKSGPTTIHIPLSGNKTGTKGPTVNIPQEAVNRTAVWQQINKDGNGISEQLIIPVTLKVRQINGNHAPSSATLSPRLSPMHEADEYSEAPTNSPAHPAGNQQQQQQQINNCKEAAKLDGSCSNNSQISPANITPV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53838-1", "uniprot_id": "BOR1_YEAST", "id": "P53838-1", "name": "Boron transporter 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNESTRVTVSRGCTASDECAQALERTNDELDRESSVS------------------------------------ESRSDEESHEKLSRRRFPTLGIGIWLDLKDRIPYYKSDWVDAFNYRVIPSIVDTYFNNLLPAIAFAQDMFDRTDNSYGVNEVLLSSAMAGIVFGVLGGQPLCIVGVTGPISIFNYTVYEIIKPLNTSYFGFMFWICMWSMIFHLVLAFTNAVCLLQYVTTFPCDIFGLFINVVYIQKGIQILTRQ----------------------------------------------------FSAKSGEKSVQDG--------------FASVVVALVMTAFGLFFKLFHYYPLFSHRIRTFISDYSTALSVLFWSSFTHFGGYLHDVKFKKLPITKAFFPTSKVNRPQNTWLAYEPIPVKDVFIALPFGIFLTILFYFDHNVSSLMAQRHQYKLKKPSSFHYDFALLGLTTCISGVLGIPAPNGLIPQAPLHTETLLVRDS------NQKVISCVEQRFTNTFQGLMILGTMTRPLLVCLGEIPQAVLSGLFFIMGINGLMTNSIIQRLVFLFSDPNRRDNTSPLMKVSKKSMLIFLSFSLTGFAGEFAIT-NTIAAIGFPLVLLLSVLVSFSFAYIFPTEELKILDTNVAQKFTIKNLLLENIRDAKFCDKHED--------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : . . : . . *. :: ** : :. .: : * : *: *:* : *:: ** **:. : :.* : * : * *:*. : : * .. * *... : *: :..:.**** *:* ***: :*: :::: .*: : * :* : ::*. :* .*: *:* *. : *. :* .::* :.:: : . .. * : .*:: :. .:* *: *. :* ***::. :::. . : * : ** :.. : ** . . : * : * .:: ***:::*::::::: :*:: *** ** .** *:*: **: .* .:::*: :: .: : : * *. : :* ..*: : : *. : ::: **:::: : : : *. .**. ** :.: . : . : . ", "identical_positions": 89, "similar_positions": 174, "identity": "6.45%" }, { "cls_id": "homologset.agr.MGI:2443880", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDP7-1", "uniprot_id": "D3ZDP7_RAT", "id": "D3ZDP7-1", "name": "", "aln": "MNLLYRKTKLEWRQHKEEEAKRSSSKEAAPTGPVGSGAVPGPGVRVRDIASLRRSLRMGFMTMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGGGGGLLEDSSTRRPPAKPRRHPSTKLSMAGPG--AETPPSRKAGSQKPTPECRESSRKVPPQKPRRSPNTQLSVSFDESCAPAPSPRGGNLPLQRLSRASRIAGDLDAGAQEEEPVYIEMVGDVFRGGGRSGGGLTGPPLGSGGPTPPAAADSDSEDSEAIYEEMKYPLPEETGDGRANGPPPLMAPSPPQQPHVLQPHPHPHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRAPGDGVSRLPVLCHSKESAGSTPAPQVPARERETPPLPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQTRGERELPNSHSMICPKAAGVPAAHPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGVGEPKTE-EISVLHGMLCASSRPPVPGKSSPHSGAMGSAAGVLHHRSCLASPHSLPDPTAGPLTPLWTYPATAAGLKRPPAYDSLKAGGVLSKGCGMGAPSPMVKIQLQEQGTDGGAFASISCAHVIASAGTPEEEEE--MGATFGAGWALQRKVLYGGRKAKEVDTEEDGARAWNGSTEGPGKVEHEDRGSVASGIPVRSQGAEGLLARIHH-DRGGSRTALPVPCQTFPACHRNGDFTGGYRLGRSASTSGVRQAALHTPRPCSQPRDALSQTHPVLPLPLP--PQPARERDGKLLEVIERKRCVCKEIKARHRPDRGLCKQESMPILPSWRRGPEPRKSGTPPCRRQHTVLWDTAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFX7-1", "uniprot_id": "NYAP1_MOUSE", "id": "Q6PFX7-1", "name": "Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1", "aln": "MNLLYRKTKLEWRQHKEEEAKRSSSKEAAPTGPVGPGAVPGPGVRVRDIASLRRSLRMGFMTMPASQEHTPHPCRSTMAPRSLSCHSVGSMDSVGGGPGGG---LTEDSSTRRPPAKPRRHPSTKLSMAGPG--AETPPSKKAGSQKPAPECRESSRKVPPQKPRRSPNTQLSVSFDESCAPAPSPRGANLPLQRLSRASRITGDLDAGAQEEEPVYIEMVGDVFRGGGRSGGGLAGPPLGSGGPTPPAAADSDSEDSEAIYEEMKYPLPEEAGDGRANGPPPLTAPSPPQQTHILQPHPHPHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRAPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPLPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQTRGERELPNSHSMICPKAAGVPAAHPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGVGEPKTE-EISVLHGMLCASSRPPVPGKSSPHSGAMGSAAGVLHHRSCLASPHSLPDPTGGSLTPLWTYPATAAGLKRPPAYDSLKAGGVLNKGCGMGAPSPMVKIQLQEQGTDGGAFASISCAHVIASAGTPEEEEE--MGAAFGAGWALQRKVLYGGRKAKEVDTEEDGARAWNGSTEGPGKVEHEDRGPVPSGIPVRSQGAEGLLARIHH-DRGGSRTALPVPCQTFPACHRNGDFTGGYRLGRSASTSGVRQAALHTPRPCSQPRDALSQTHPVLPLPLP--PQPARERDGKLLEVIERKRCVCKEIKARHRPDRGLCKQESMPILPSWRRVPEPRKSGTPPCRRQHTVLWDTAI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZVC0-1", "uniprot_id": "NYAP1_HUMAN", "id": "Q6ZVC0-1", "name": "Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1", "aln": "MNLLYRKTKLEWRQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFMTMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRHPSTKLSMVGPGSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVSFDESCPPGPSPRGGNLPLQRLTRGSRVAGDPDVGAQEE-PVYIEMVGDVFRGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALP--PHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEPKTEKEISVLHGMLCTSSRPPVPGKTSPHGGAMGAAAGVLHHRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAPSPMVKIQLQEQGTDGGAFASISCAHVIASAGTPEEEEEEVGAATFGAGWALQRKVLYGGRKAKELDKVEDGARAWNGSAEGPGKVEREDRGPGTSGIPVRSQGAEGLLARIHHGDRGGSRTALPIPCQTFPACHRNGDFTGGYRLGRSASTSGVRQVVLHTPRPCSQPRDALSQPHPALPLPLPLPPQPARERDGKLLEVIERKRCVCKEIKARHRPDRGLCKQESMPILPSWRRGPEPRKSGTPPCRRQHTVLWDTAI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************.**:*..*..* ************************************:***********************. * **********************.*** ******:*******:** ****************************.*.*****.*******:*.**::** *.***** *********************:*****.*******.******:***************:*:********* *.*****.* * **.*************************************************:****************.****************** ********************************.*******************.*** ****************************************.****** **********:*********:***.****:********.************ *.********************:********.****:***************************************** .*:********************:*. **********:*******:****. .******************* **********:*******************************..****************.**.****** ************************************************* ***********************", "identical_positions": 760, "similar_positions": 55, "identity": "90.05%" }, { "cls_id": "homologset.agr.MGI:2443881", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PW37-1", "uniprot_id": "E9PW37_MOUSE", "id": "E9PW37-1", "name": "", "aln": "-----------------------------------------------------------------------MELSPSSGGAAEALSWPEMFTG----------------------------LESDSPLPPEDLDAVVPVSGAVAGGMLDRILLESVCQQQSWVRVF-----------DVKGPPTHRLSCGQSPYTETTSWERKYCILTDSQLVLLNKEKEMPVEGQDQ-QTDSTKGRCLRRTVSVPSEGQFPEYPQE-GTTKLEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNAD-DRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLS-GSKCFSCSSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKK----KYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTP--------------NKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFITSNYTMLCSVLEPVISVRNKEE-----LACALVHILQSTGRAKDFLTDLVMSEVDRCGEHD--------------VLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSS-------ELMDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLIS---ASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISN---PDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLAD--------------------------------------------------------------------ITKSLTNPTPIQQQLRRFAEHSSSPNVSGSLSSGLQRICEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYS-------EKDEKENSLPNGRSISLMDLQDTHAAQAEHASVMLDVP---MRLAGSQLSITQVAS---------IKQLRETQSTPQSAPQVRRP------------------------------------------------------------------------------LHPALNQPGSLQPLS----------FQNPVYHLN-------------------NPVPAMPKASADSSLENLSTASSRSQSNSEDFKLSGP------------------------SNSSMEDFTKRSSHSED----FSRRHTVPDRHIP---------LALPRQNSTGQSQIRKLDHSGLG-------ARAKAPPSLPHSASLRSTGSMSVASAALMAEPVQNGSR-------------------------------SRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEITKLKERLRVSS----------------RRLEEYERRLLVQE--QQMQKLLLEYKARLEDSEERLRRQQE------------EKDSQMKSIIS-----------------------------------------------------RLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQ-VRNGISPTNPTKLSITENGEFKNSSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ABU3-1", "uniprot_id": "A0A8I6ABU3_RAT", "id": "A0A8I6ABU3-1", "name": "", "aln": "-----------------------------------------------------------------------MELSPSSGGAAEALSWPEMFSG----------------------------LESDSPLPPEDLDAVVPVSGAVAGGMLDRILLESVCQQQSWVRVF-----------DVKGPPTHRLSCGQSPYTETTSWERKYCILTDSQLVLLNKEKEIPVDGQDQ-QADSTKGRCLRRTVSVPSEGQFPEYPPE-GTAKLEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNAD-DRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLS-GSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKK----KYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTP--------------NKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFITSNYTMLCSVLEPVISVRNKEE-----LACALVHILQSTGRAKDFLTDLVMSEVDRCGEHD--------------VLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSS-------ELTDHQSNLRMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDLSERLIS---ASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISN---PDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDK-------ATVAKLGPLPRVLAD--------------------------------------------------------------------ITKSLTNPTPIQQQLRRFAEHSSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYS-------EKDEKENSLPNGRSISLMDLQDTHTAQVEHGSVMLDVP---MRLAGSQLSITQVAS---------IKQLRETQSTPQSAPQVRRP------------------------------------------------------------------------------LHPALNQPGSLQPLS----------FQNPVYHLN-------------------NPVPAMPKASADSSLENLSTASSRSQSNSEDFKLSGP------------------------SNSSMEDFTKRSSHSED----FSRRHTAPDRHIP---------LALPRQNSTGQSQIRKLDQSGLG-------ARAKAPPSLPHSASLRSTGSMSVASAALVAEPVQNGSR-------------------------------SRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEISKLKERLRVSS----------------RRLEEYERRLLVQE--QQMQKLLLEYKARLEDSEERLRRQQE------------EKDSQMKSIISRLEDHLLSGEERKEKAITIKEVSCKETQAVSSSFSVSSSPVFVSTDTFFPPHSRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQ-VRNGISPTNPTKLSITENGEFKNSSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UJF2-1", "uniprot_id": "NGAP_HUMAN", "id": "Q9UJF2-1", "name": "Ras GTPase-activating protein nGAP", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQTPEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRSTD-DRSRGLPKLKESRSHESLLSPCSTVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLS-GSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKK----KYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTP--------------NKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEE-----LACALVHILQSTGRAKDFLTDLVMSEVDRCGEHD--------------VLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSS-------ELIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLIS---ASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISN---PDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLAD--------------------------------------------------------------------ITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYS-------EKDERESSLPNGRSVSLMDLQDTHAAQVEHASVMLDVP---IRLTGSQLSITQVAS---------IKQLRETQSTPQSAPQVRRP------------------------------------------------------------------------------LHPALNQPGGLQPLS----------FQNPVYHLN-------------------NPIPAMPKASIDSSLENLSTASSRSQSNSEDFKLSGP------------------------SNSSMEDFTKRSTQSED----FSRRHTVPDRHIP---------LALPRQNSTGQAQIRKVDQGGLG-------ARAKAPPSLPHSASLRSTGSMSVVSAALVAEPVQNGSR-------------------------------SRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLKERLRVSS----------------RRLEEYERRLLVQE--QQMQKLLLEYKARLEDSEERLRRQQE------------EKDSQMKSIIS-----------------------------------------------------RLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQ-VRNGISPTNPTKLSITENGEFKNSSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BIR4-1", "uniprot_id": "A0A8M2BIR4_DANRE", "id": "A0A8M2BIR4-1", "name": "", "aln": "MSLTRLATLEEQTGSNRSPSRSSFGKDSVRRWRLLNRPWLKHRSNSAPEEPLDMHDRRILVRQDMRTQSLTWSRSSSTRPSNPPISRVHSLPDPQRVTSRGVLLEHANLQKDWLSRSSSPFFKSTSELGSEIHTGAPPLRRVSSSHMFSGILLSMSRRISRILNTSPEPAVGELSEDDVKGPASHHFSCGQSPFTEPCVWERKYCILTDSQLILLNKEEEMPSEVHESPSASSSKGRSLRRTVSVPSEGPFPDFPPEGASMIAEASAERSPRRRSISGLGSSEKNISIDGPNSSPFKVPGFLSKRLKGSIKRTKSQTKLDRNTSFRLPSLRPTENDRSRGLPKLKESCSHESLLSPGSAVEALDLSMEEDVYIKPLHSSILGQDFCFEVAYSG-GSKCFSCSSAAERDKWMENLKRTVQPNKDNCRRAENVLRLWIIEAKDLPPKK----KYFCELCLDDMLYARTTSKTRSDCLFWGEHFEFSGLPSMKSITIHIYRDVDKKKKKDKNNYVGLVNIPVHGVMGRQFVEKWYPVSTPTT--------------SKAKGGGPSIRIKSRFQTISILPMEQYKEFAEFVTNNYTMLCSVLEPVISVKNKEE-----MASALVHILQSTGRAKDFLTDLVMSEVDRCADHD--------------VLIFRENTLATKAIEEYLKLVGQKYLHDALGEFIKALYESDENCEVDQSKCTSN-------ELPEHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCHARGKQDISQRLIS---ASLFLRFLCPAIMSPSLFGLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWAGMTRFLLEISN---LETISNTPGFEGYIDLGRELSVLHSLLWEVVSQLDKGDNSFLQATVAKLGPLPRILGD--------------------------------------------------------------------ITRSLSSPTPIQQQLRRFQDHSSAHDISGSVSSGLQRIFEDPADSEMRSIKSPVQEHMEALVRGKHPLLGQQSSAHSMSFS-------DKEERDSPLPNGRSISLMDLQDSYLAQGHPGPNSLNEASSRLGRVGSQASIGPVPPPHLHQPPVHPKVPQLRDNLPQSAPQVRRP------------------------------------------------------------------------------IHPSLSQQRSLQPLS----------FQNPVYHLSNLHAQSTHS---------TQSTHSAQSLQPDSSSENLSTGSSRSASPSASGGRGATPR-----------------ARIPSTSSVEEEFSRRSIQGQETPPPTARWHPPLADQHSG-----AQVVAVPRQSTTGTAHIVKVEQQSRGVGLVAANAGARTPRSLPHSTSIRSG------SSANTEPIQQSGER-------------------------------SRQQSTCSKDGSVPGGRAN-----KQVQSPVESVTMSPVERTAAWVLNNGQYEDEEEEG-QSKDDAKHVEKYEQEISKLKERLRTSS----------------RRLEEYERRLLAQE--QQMQKLLLEYKTRLEDSEDRLRRQQE------------EKDSQMKSIIC-----------------------------------------------------RLMAVEEELKRDHAEMQAVIDAKQKIIDAQEKRISSLDAANSRLMSALTQVKERYSMHNLRNGLSPTNPTKLSITENGEFKNSSC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T498-1", "uniprot_id": "GAP2_DROME", "id": "Q8T498-1", "name": "Ras GTPase-activating protein raskol", "aln": "------------------------------------------------------------------------MGRRTYLSRSSTISYPSRIEG----------------------------WLDVCETEGELTRLIKTLPWGPLYCVLQQDDQTFTAYCSEEISLG-----------DVCYEDIPRVRLDRVRRPAKALWDGPPTLVEENEDSDSCVGGSGGMSGINDIVLNTTLYSELGEYKSKTLPRIHFDTALNDTSLNEDTSYEKACRRGSAP-TTPILGSKQHQTEHNATSRFTNFFSKKSN-PLKRTKSVTKLER---------------TKRGSGGLRGSRSHESLLSSHAVMSTIDLSCTGAVGVAPVHQSVLGRRHCFQVRGGPRGERYYSCGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKK----RYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILSDKAGDSLGRTSGGGGSGSKDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKED-----IGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQ---------------RLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSS----AGSLQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGRQDMADNLIS---ASIFLRFLCPAILSPSLFNITSELPSARATRNLTLVAKTLQTLANFTRFQGKENFMEFLNDFLEQEAARMQQFLEIISTRPEHPAPDSILDWAGYIDQGKQLSILHSLLSESLAKLPEARQHELDPLQHILDEISRAKEHGMGTALPGGYLPATSSTHSIASENQENRNPGSSGSHAGSNSEQLLPQQSQLAQPQHAIVSKPLSAERGIMRGVLTPNSLEKNIFRYNDPTVNGLLQQQQQQQQQQQQQQQQHQQLQQHGHQQQPHHQHPLQMLSNSQTSIAGNQYMSSPGGLQHAQSQTSMASSSLNGSSSNLLHGHQQHAHHPQQLHPHHCPPAPQTSASSTMERMDRMNYPYMSHNGNDYETSTPSSTRSRTLPRNGNPNANGNVGSSNNNQSGSYDDMHGEFQIQISGFDTSSAFVCKSPTPMMKSSLGPAGAGRSHHKLNLGIPDHSGGYVRGNNLNPNSNMPKNLEDLDDLFKYAEEHDVAEPANHHNHNQGQQNHQGHLKPAAVPGKEQLSAKSSHCSSGYQSISTNPSPSQSSSPVESQLKAAMGSHNAPLAFKNPSYQLQPQTGSSRSSAQSNTHQQQQQQQQQQFGSRLKPIGGGLVAARAAFLNSGGALEAATLTPSSSDEQLSADNYFSYAAAAAAGAGIATKLEAQRSLSGGSSSSTSASASTSNLGKSGGSSAYGRLNGPLKREDVYGSGYGGSSGNVGYGLSTSSAAGHHQHPHQQQQNPMQQQQQRERDQEHKQYAGSVAGSVGSATSAAQRRLSLDSARTLSDSSTDTEGHCNQLQEGKRRRQLRSSGGSGGGGAGSEQGLGKSYDQNGEIQLLQQTLDTLCHTLDRDEAELRDSSDELFGLQRPAGSNGSNNLSLQSESTMRSIID-----------------------------------------------------RLITMEEELRREQLKMSLALSHKQRVIEEQGQQIAALDAANSRLLSALTALRQRYETQ--QQQQQHQAPPKTQKPQ---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33314-1", "uniprot_id": "BUD2_YEAST", "id": "P33314-1", "name": "Inhibitory regulator protein BUD2/CLA2", "aln": "----------------------------------------------------------------MSSNNEPAQSRTSYFKLNEFLSNVKHYKNTFKG---------------------EIQWCNNLSLNDWKTHYLQITSTGALTHSIDELTADSTNIQPIIKHLQQCR-----IEIIKDKHSSFKDINANCNFIIQVNTSGKDNKVYLRVKSWSDFKKLLTCLIWWSSMKTNGIFNKFQVSRPLEFKSKKMAKPESLLVYKLNVFGPIVKNIVLPPATNILESPDIINNDDNSVGWFSAMGVLKSNGMLDLLLQ-SDGSLIYSLNISQLLRSEIRILDSSVLQSENSLFLGELPLLRSQLGLEKFRIENIASAATNSSDISQEIIVEFPLRIDLEDCFIALQSFARSEYLSITGSDKSNDMKISNSFKISILEANFQSINLNDKNNTPWSIFTDITAWGHTWARTSMVSNSSNPFWREEFQFNELLRLTNSYLEIKQLFHDLNNKKRLRLIGKIKITQEIINDTRYNKETRLPIMDVD---------------NKNFQIGTICIKISSNLNFILPSTNFVKLEKLLMNANLSMVSNLIYKSSSSMENDNKLTQTSIIFLDIFQSLSRIEEWFHVLIDKELAKIDGTVSRINQKNLDSKHVFNSLFRGNSILTKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYKRLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNGISGLLFLRFFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFANKEPWLMKMNNFIDKRHNDLLDYIDKMTQ---------------------KKLDFNSKILNLSSTISRPKLAIEQTMLDDLPQIPYLLDK---------------------------------------------------------------------------------------------NLRETEFVNLIVNFSQEDMTKMEKYNHMDNGGKGELIEEEGLLS---GSSLNLSVD--------KKDLDSPIEVKPEIGELEFEKITENNTEIFG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDLMNLLKSDDVGSRSRDLDNGANSGIKFNSIIPKAEE------------------------EKHAMKELEQESCLLYN--RINHIRKRLSG------------------------------------------------------------------------------------------------------------------YECASSTLFEDKKYSISLSHKIFYEEIKEGKEIVLKLLNKPTNENSSARLQKFFTKGVSSKSNNTVGDSYCKFLTIDVSDENPKS---------------------------------SNKTSVHGTSSENGAKDD------------------------------------------------------------------------------------YLTLPNSQGKGNLGNRFSPTKLSRIMRKPPNADVPKEQNSRKLTRWFKKKKETGGS----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . : ..: .. : : : :. . :. . . . . . *. :: : . :.* :.: .:. . : . . *. :: : . . . : :: :* *: * :: :.**: .:. ** *.*:* : : :.: : ... :::.: . :* ::*. : . :: : : :: ** : *** : :: : . : . * . ::: . :: :::: . :: :: :: : ** *:: **::* :: .*::** .:*. :: : :*:..**:* :: . . : : * : : : :* :::: : :::: :* : ::. . :****:**.*:.*.** .: . : *.***::*.: .*:.:::* .** :: :*:*:::. : :: :: : ::* : : : : . . * :. . : .: .:.. : .. .. :: : . .. . . :. .. : . . . .* ..:.. .. . . . :. :.. : : ..: . . : . . .: . . .. . : : : : . * : .:. ..: ::: :. : : .::: : . : . :* :. :: ", "identical_positions": 64, "similar_positions": 301, "identity": "3.55%" }, { "cls_id": "homologset.agr.MGI:2443882", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CE50-1", "uniprot_id": "SNX30_MOUSE", "id": "Q8CE50-1", "name": "Sorting nexin-30", "aln": "-MAGGPPKALPSTGPQSLRDMPHPLAGSSSEEAVGGDSTPSPDLLMARSFGDKDLILPNGGTPAGTASPASSSSLLNRLQLDDDIDGEARDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVV-DRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAYKKQGIALLSRVGESVK--HVTGGYKLRSRPLEFAAISDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGP----VYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDITEEFLPVLREYVLYSDSMKGVLKKRDQVQAEYEAKLEAVALRKEER----------------------------------------PKVPADVEKCQDRMECFNADLKADMERWQSNKRHDFRQLLVGLADKNIQYYEKCLMAWESIIPLLQEKQETK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A060-1", "uniprot_id": "D4A060_RAT", "id": "D4A060-1", "name": "Sorting nexin-30", "aln": "-MAGGPPKALPSTGPQSLRDMPHPLAGSSSEEAVGGDSTPSPDLLMARSFGDKDLILPNGGTPAGTSSPASSSSLLNRLQLDDDIDGETRDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVV-DRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAYKKQGIALLTRVGESVK--HVTGGYKLRSRPLEFAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGP----VYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDITEEFLPVLREYILYSDSMKGVLKKRDQVHAEYEAKLEAVALRKEDR----------------------------------------PKVPADVEKCQDRMECFNADLKADMERWQGNKRNDFRQLLVGLADKNIQYYEKEMG------PILVHASSHN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VWJ9-1", "uniprot_id": "SNX30_HUMAN", "id": "Q5VWJ9-1", "name": "Sorting nexin-30", "aln": "-MAGGPPKALPSTGPHSLRDMPHPLAGSSSEEAVGGDSTPSPDLLMARSFGDKDLILPNGGTPAGTSSPASSSSLLNRLQLDDDIDGETRDLFVIVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEKFVVKGVV-DRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAKDLNAYKKQGIALLTRMGESVK--HVTGGYKLRTRPLEFAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGP----VYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKEDR----------------------------------------PKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESIIPLLQEKQEAK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q566W7-1", "uniprot_id": "SNX30_DANRE", "id": "Q566W7-1", "name": "Sorting nexin-30", "aln": "MSNGGTPRSLPSSGQKSIQEICHPLS---AEESAR---SRSPDVLNP---GEKDLSLPNG-TPVDTSSPASSSSLLNRLQLDDDLDAETRDLFVTVDDPKKHVSTMETYITYRVCTKTTRTEFDLPEYSVRRRYQDFDWLRIKLEDSQPTHLIPPLPEKFVMKGVV-DRFSEEFVETRRKALDKFLKRVADHPVLSFNEHFNAFLSAKDLN--KRQGLALLTKMGESVK--YVTGGYKLRGRPVEFAAMGEYLDMFTQKLGTIDRIAQRIIKEQTEFLMELREYGP----VYSSWSSFEEDLHEPLEGVSGCVSNCSSALEELTEDMSEDFLPVLREYVLYIESMKNVLKKRDQVQAEYETKLEAVVFREDKK----------------------------------------TPMPTDVEKCQDRVECFNADLKADWDRWQNNKRQDFRQLLTGMADKNIQYYEKCLAAWESLIPLLQDKQDAKGETN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P47057-1", "uniprot_id": "SNX4_YEAST", "id": "P47057-1", "name": "Sorting nexin-4", "aln": "---------MTDKGKNDLTSK--------AKDKARGNPEKPP----------YWFEIIVSDPQKRTGDPGSSSGYVS-YQISTKTN--NTSFYDNRGDPE-------------------------SIIVVHRRYSDLLLLHDILLNRFPTCIIPPLPDKKVFQYIAGDRFSQRFTQKRCHSLQNFLRRVSLHPDLSQSKVFKTFLVSKDWESHRKVLQDSLQPNKDEVTDAFMNAFKTVHKQNEEFTEIREKSDKLDRTVTKIDKLFHKVVKKNDSMSEDYTKLGSNLQELQELVTGENEELAAKLKIFNEGVTQLSYGLQDLTKYLDYEYIVDLKDLEHYIDSMRQLIKLKDQKQIDYEELSDYLTRSIKEKNNLISGYGGSNFFANKLEELAGINQEASRREKINKLEGKITSLTGELENAKKVADGFEQECLKEIDHFESVKTAEIKKSLGSLADHHIEFYERILEAWEKVDDSL-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :...* :.: . ::: . .* : : . . *..*.***. :. *:. . : .:: .**: . *:***.*: *: * : ** :*****:* *.: :. ****:.*.:.* ::*::**:*:: ** ** .: *: ** :** : :: * :.*. .:.. .:: : **: : : * : .: .**:: ::::*:: . : : *. : . :. : :* *: .. : : * .*::**. : ::: *:: * :**: ::* :** : :** : :. ..: . :. ::*:.:. : *: : : ::::. * :::: * .:**::*::**: : * ", "identical_positions": 79, "similar_positions": 157, "identity": "16.16%" }, { "cls_id": "homologset.agr.MGI:2443883", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LED7-1", "uniprot_id": "A0ABK0LED7_RAT", "id": "A0ABK0LED7-1", "name": "Multifunctional fusion protein", "aln": "---MLPPALLRRSLLSYAWRGSGLRWKHASS-------LKVANEPILAFT-QGSPERDALQKALNDLKDQTEAIPCVVGDEEVWTSDVR---YQLSPFNHGHKVAKFCYADKALLNKAIEAAVLARKEWDLKPVADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISV--PPSTNHVVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNVIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDR--FRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPQSLWPQIKG---RLLEEHSRIKVGNPAEDFG-----TFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYFVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDEKYRETLQLVDSTTSYGLTGAVFAQDKTIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGEWRVPGQPRLVQLWTEPPFTPLAVSPPLGDWRYSYMQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHT0-1", "uniprot_id": "AL4A1_MOUSE", "id": "Q8CHT0-1", "name": "Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial", "aln": "---MLPLPSLRRSLLSHAWRGAGLRWKHTSS-------LKVTNEPILAFS-QGSPERDALQKALKDLKGQMEAIPCVVGDEEVWTSDIQ---YQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISV--PPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDR--FRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKG---RLLEEHSRIKVGDPAEDFG-----TFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLQLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKP-LGDWRYSYMQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30038-1", "uniprot_id": "AL4A1_HUMAN", "id": "P30038-1", "name": "Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial", "aln": "--MLLPAPALRRALLSRPWTGAGLRWKHTSS-------LKVANEPVLAFT-QGSPERDALQKALKDLKGRMEAIPCVVGDEEVWTSDVQ---YQVSPFNHGHKVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISV--PPSTNSTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDR--FHTFPRLAGECGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKG---RLLEEHSRIKVGDPAEDFG-----TFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKP-LGDWSYAYMQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7SY23-1", "uniprot_id": "AL4A1_DANRE", "id": "Q7SY23-1", "name": "Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial", "aln": "-------MLRARSAVSQSWKG--FKTFSCVA-------VEVKNEPVLEFK-EGSKERAELEEALRNLKGKTEEIPCVIGNEEVWTKDIR---FQLSPFNHSHQVAKFCYADKDLLNKAIEASVAARREWDLKPVSDRAQIFFKAADIISGPKRAEVLAKTMIGQGKTVVQAEIDAAPELIDFFRFNAKHAIELEDQQPLDS--DGSTNTMLYRGLEGFVAAVAPFNFTAIGGNLAGTPALMGNVVLWKPSDTAMSASYAVYKILRESGLPPNIIQFVPADGPVFGDTVTSSEHLAGINFTGSVPTFKRLWKQVAQNLDI--YKNFPRVAGECGGKNFHFVHKSADVRSVVTGTIRSAFEYGGQKCSACSRMYVPDSLWPQIRQ---GLLDVYKQIKVGDPVEDFS-----TFFSAVIDDKSFSRIKGWLEHARSSPHLKIIAGGNCDDKKGYFVEPTIIETTDPQEKIMNEEIFGPVLTVYVYPENDYKKVLHLIDNTSPYALTGAIFPQDKSVIEEAGKALRNAAGNYYINDKSTGSIVAQQPFGGARASGTNDKPGGPHYVLRWTSPQVVKQTHVP-LTEWKYPYMS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNX4-1", "uniprot_id": "Q9VNX4_DROME", "id": "Q9VNX4-1", "name": "Multifunctional fusion protein", "aln": "MLRMMRSSSSRCSSLQQSLLKSSTRCLGSVIPDLKLKDFPIANEPILGYL-KDSKERKALEQALKGTASSCEDIPIVIGGKEYKTPEVR---YQVMPHDHQHKLASFYYADKKLIEKAIKTAVETQPKWDRVSIADRLKIWEKAADLMATTYRQDLNAATMLGQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTKYQPISENIKVTKNSLRYRGIDGFIAAVSPFNFTAIGGNLSYTPALMGNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPVFGDTITASPHLAGINFTGSVPTFNRLWKQVGNNIDN--YVNFPRLTGECGGKNFHFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKE---GLVCEAAKLKIGD-VQDFS-----SFTSAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDSKGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQPFGGGRMSGTNDKAGGPHYILRWTSPQSIKETFVP-LRDVNYPYMCE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P07275-1", "uniprot_id": "PUT2_YEAST", "id": "P07275-1", "name": "Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial", "aln": "---MLSARCLKSIYFKRSFSQLGHIKPP----------KHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVES-ADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYE-LTDFKYPSNYE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : ***: : . : *. :* . :* *:..:. : : * * :* : :*.. * : : .*:.:: :: .* .. ** :: ****::: * :: * **:**.*.. *****. .** **:* . . :: **:. : * ** ::**: *::*******..** :****** *:****:** :.: : ::.*:*:* .:::*:*.* . * : :. .: .::****. .*: *: :: ..: : :**: ** ******::* **:: .* .*:*.:**: ******.**:*:*.* :: :: : :. .. :. * ..**. ::* :: :*.*:..* * *: ** ... *::* * :: :. *.. *. *:***:*::* * : . : .::..:: :.****:* :*. :: * . :: :***:*****.**::*.** ***.* ** .* *. : :.. * : *. ", "identical_positions": 162, "similar_positions": 192, "identity": "27.46%" }, { "cls_id": "homologset.agr.MGI:2443884", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8E2-1", "uniprot_id": "G3V8E2_RAT", "id": "G3V8E2-1", "name": "Striatin-interacting protein 1", "aln": "---------------------MTKKGKTSGGDWQLRLSTHAATLNMAIGEISWRKSRESCLTEAIRELSRGCGAAKMEPAAAGPGPLIVNNKQPQPPPPPPPATAQPPPGAPRAAGGLLPAGK--AREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELAELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQFWMRYNIFLLLEVGT----------FNALVELLNMEIDNSAACS---SAVRKPAISLADSTDLR------------VLLNIMYLIVETVHQDCDGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFG----------MVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRTLLGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDD-----------------DNSLEGEAFPLERDEVMPPPLQHPPTDR--LTCPKGLP---------WAPKVREKDIEMFLESSRSKFIGYTLGSDTDTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVN---------------RHKEVIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVNELPELTAESLEAG---DNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRT-----HSNPDFLPVDNCLQS---------------------------------------VLG-----------------------QRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C079-1", "uniprot_id": "STRP1_MOUSE", "id": "Q8C079-1", "name": "Striatin-interacting protein 1", "aln": "----------------------------------------------------------------------------MEPAAAGPGPLIVNNKQPQPPPPPPPATAQPPPGAPRAAGGLLPGGK--AREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELAELYSYTEGPEFLMNRKCFEEDFRIHVSDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQFWMRYNIFLLLEVGT----------FNALVELLNMEIDNSAACS---SAVRKPAISLADSTDLR------------VLLNIMYLIVETVHQDCDGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFG----------MVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRTLLGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDD-----------------DSSLEGEAFPLERDEVMPPPLQHPQTDR--LTCPKGLP---------WAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVN---------------RHKEVIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVNELPELTAESLEAG---DNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRT-----HSNPDFLPVDNCLQS---------------------------------------VLG-----------------------QRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VSL9-1", "uniprot_id": "STRP1_HUMAN", "id": "Q5VSL9-1", "name": "Striatin-interacting protein 1", "aln": "----------------------------------------------------------------------------MEPAVGGPGPLIVNNKQPQPPPPPPPAAAQPPPGAPRAAAGLLPGGK--AREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQSWMRYNIFLLLEVGT----------FNALVELLNMEIDNSAACS---SAVRKPAISLADSTDLR------------VLLNIMYLIVETVHQECEGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFG----------MVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRSILGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDD-----------------DNSLEGETFPLERDEVMPPPLQHPQTDR--LTCPKGLP---------WAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVN---------------RHKEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAG---DSNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRA-----HSNPDFLPVDNCLQS---------------------------------------VLG-----------------------QRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803T2-1", "uniprot_id": "STRP1_DANRE", "id": "Q803T2-1", "name": "Striatin-interacting protein 1 homolog", "aln": "--------------------------------------------------------------------------------MDGVG-LCANNKQKQ--------------------NQMLPNKM--RGEFTRNQRKDSEGLSEAPDLEFEYSDADKWTAELSELYSYTEGPEFLLNRKCFEEDFHTHLPDQKWTELDSVQRRAHAMRLLDGLEVIGRERRLKVARAILYMAQGTFGECSSELEVQHWMRYNVFLLLDVGA----------FTALVELLNMEIDNSAACS---SAVRKPAISLADSTDLR------------VLLNIMYLMVETIQREEPTDSPEWRTIRETFKSELGSPLYNHEPVSVMLFG----------MVTKFCSGHAPHFPMKKVLLLLWKTILFTLGGFEQLQSCKISRRAALGLPPLPEDSIRVVRSMRAASPPASASDLIEQQQRRARREHKALIKQDNLDTFNEKDPYKADDSHEDEEENDDN----------------DNSLEAEPFPLERDEVMPPPIPHPPTER--MCFPKGLP---------WAPKVREKDIESFLESSRSKFIGYTLGNDTDTVVGLPRPIHESIKTLKQHKYVSIAEVQIAKEEAFQKTPLSGGEEELELCATELLYQGILPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVN---------------RHKEIIVKAISAILLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISALDFPHCVIHELPELTAESLEAG---DNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKGNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNSRRYDKN-----QSNPEFLPVDNCLQS---------------------------------------VLG-----------------------QRIDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRD5-1", "uniprot_id": "Q8IRD5_DROME", "id": "Q8IRD5-1", "name": "", "aln": "---------------------------------------------------------------------------MAWKQKNKLLFDTCKNQLSCGAVNARSSMMQSIQSRINVLNTIAASSKRIERASVDTDTHDADANCDGPDLDFVYADVDGYQNEIAELYSYTEFSEFQMNVKAFEDQMELYDLPPNWQKQDSASQRGIVMKLVDQLEVSDRSFRMQAARCILYLAQGCWAEVQSDEEQHQITRDNVLVLYQLGV----------FASFIDLLNMEIES--ACSPDIVAVKITNVTLVDSTDIR------------VILSVLYIITETIRDEKEKGSEDYRELADSFVQEINSPLPDGELLAVKLLG----------MITRFCSGAAPQFPMKKVVLLLWKVSLLGLGGMDVLKNLKNEYRLKVGLEPITEDTLEVTKCMRASSPPATATDILENQYPK-RNFKRSLMKQRFLDEPEQIDMEMGGNEGQNNANNGSGNGGNGEEELSQYYRPYDDPSSSASTTSTANPNNQPSLTQPPAAVPPVQITARLP---------WTPKVRQKDIDQFLDISRNKFIGYSLIGDHESLAGLPQPIHEGFKTLQRHMYMSLADVQIKKEEDIARNPISTHEDEIKLTPAEVLYQAILPNLPQYMIALLKVLLAASPTSKSKTESINIMADVLPRKMPLTATQSTKLTVDIG---------------RHKEIIVKAVSAIILLYLKHFKINHVYQFEFMSQHLVFANCIPLVLKFFNQTITEYVNTKNSIPLLDFPSCVIGEQPDLSGDSFVYGGEMSDKSYSWRNVFSCINLLRILNKLIKWKHSRVMMLVVFKSAPILKKTLKVRHAMMQLYVLKLLKMQTKYLGRQWRKSNMKTMSAIYAKVRHRLNDDWAFGNDLESRPWDFQAEECTLRACVDRFNLRRYPEATQKCGNNGTAAQNAENAQQSNMMAGNNGCGNNGDANGYGNNGGGGNGGHNQQQQLNDYGVEGGFPSDEILTHSDFAFFGHSGWWDRKVELTDYFKANYAVWLEEEVYNSQTDWDAL--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53917-1", "uniprot_id": "FAR11_YEAST", "id": "P53917-1", "name": "Factor arrest protein 11", "aln": "MNASGRSHSKGPIIRSVSLEDLKRNSSFKGNLKYKDEVTSHKEPQVGTLSNEELLKDLDNMLRGKLNMGRNSFHADKRNKSDGNISALTFKARSGLEGDIRTIDIQQDSSDENDNFKFSDDGVNKDRNNEKDNNTDNAVEFQDDAEEAEEENEDESFANVDELDGFDLNKVSDGKHVPINEKGEVDYNMPVDKEFQKSLDQCAASLEERSSAPYALQRAVDWELKMFYSLEDELSEWFCSSDYMHFGQTQTLFKQKITQPQLFFDDENYAASVVECLIEDIPNSLASN--LLALSYISMGCFAFTNSKSEHTKIIRRNNLMLVPHIQEIVHAFKKIAISCRDDNRNLKKQTILLFHSSTILYFICSICIEGRGENPEAVNVVIDAFEKTDLLEFLTKYIENWRWNSRLAMR-IRNMISLLFKLIVLQFGDSSVYKQTKSSIYNLHGLTYPSKHPEKLSISPLHYQAFREDITSRFPDYNMPSSGLPKDVDKSESLSQFLEIPRP-------------KSKNPLNMALIVPEKHIATPAPSPPSSPQLMHLGEGPRPRKSFQTNMAYPCLYPSDNEGSEDDTLEDRIDLNIERKPDNDIVIPFSTEEAARILSESLEIKLSTKQLWYERDLFMITERGWKQQLENEPYDYAALNHDANSSKEEKSAICIMQRIDKYYKSCLSSFNSLVFVLLQTMESSLTNNFHRKSEVSDKNLLNMLTPQLEIVRAKELSLKSAAGILHALLKWFKLSHILKFEHLAVVIHDSRYINTCASILSKYSEVYP-ERVFNKYVQTPNSFWKECS-LSNESYRESYSVDDSGEVDTEIMPSFAYLLRILRKVTGNKTQRLKELPLSIGILFKRYYRLFNLDMYHPILKITRELTPFKNKRWKSEHMELISGVYLYEKLELTDNWVTGKDISGELSDACGQEIALRALLQFYNFQHYEIS------------------------------------------------------------------------------------------MEDLGYGHRNSSSQDLLNKESEYLNI--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * : : : * :: ** .: : :::. . : :. : . . :. ::* :. .* .. : : : :. .: :.:: * :* . *.. *: : *: : ::: : :..:.: : * : . : *. :: : * :: * . .* * : *: * : :. .* .: ::: ::. : *:. .: :. . : : :. : .: . . :. :. : . .. : .. * : : * : .* : : : .. *. .: . :. :* . .*. : *.. .:: * *. . ::::: . : .. .: : : :: *: .*:* :. ** . * : :. : ::. * **: :*: :.:: ** **:.*: :**.:: : :. * .::.: * : :: * .. * . *: :* . ... :::..: * : : . :::: : : :. . ::*: :: : * :**: : * : .::*:. :*: :*.:* : .*.*:*. *:*:... * .:* :*** :: :* ::* : : .: ..:: .. .: : ", "identical_positions": 75, "similar_positions": 272, "identity": "7.06%" }, { "cls_id": "homologset.agr.MGI:2443887", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0B1T9-1", "uniprot_id": "B0B1T9_RAT", "id": "B0B1T9-1", "name": "", "aln": "----------------------------------MAYSTVQRVALASGLVLAVSLLLPKAFLSRGKRPEPPPGPEGKLGRFPPMMHHHTAPSDGQTPGAHFQRSHLAEAFAKAKGAGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLS-KGK-TAEDRNCSTAPPGNTHRKITNFELVQLQEKLKETEEAMEKLINRVGPNGESRAQTVTSDQEKRLLHQLREITRVMKEGKFID-TSPEKEAEEAPYMEDWEGYPEETYPIYDLSDGIKRRQETILVDYPDPKEPSAEETAEQMGALDEESSEHLSWDRLPTDPGVQRDNSVTLCD---------------------------------------------------------------PKPESCSCCFHEDEDPAVLAEN---------AGFSADGYSEQEEATKENLPQDFTDEGLG---------------------------------------------------TSTDNTHVGGMLRKRSPQGFE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BPM6-1", "uniprot_id": "RIC3_MOUSE", "id": "Q8BPM6-1", "name": "Protein RIC-3", "aln": "----------------------------------MAYSTVQRVALASGLVLAVSLLLPKAFLSRGKRPEPPPGPEGKLDRFPPMMHHHSAPSDGQTPGARFQRSHLAEAFAKAKGAGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLS-KGK-TAEDRNCSTAPPGNAHRKITNFELVQLQEKLKETEEAMEKLINRVGPNGESRAQAVTSDQEKRLLHQLREITRVMKEGKFID-TSPEKEAEEAPYMEDWEGYPEETYPIYDLSDGIKRRQETILVDYPDLKEPSAEEIAEQMGEIEEEGSERLSWDHLPTDPGAQKDNSVAPCD---------------------------------------------------------------PKPESCSCCVHEEEDPAVLAEN---------AGFSADGYSEQEEATKENLPQDFTNEGLG---------------------------------------------------VSTDNAHVGGMLRKRNPQGFE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z5B4-1", "uniprot_id": "RIC3_HUMAN", "id": "Q7Z5B4-1", "name": "Protein RIC-3", "aln": "----------------------------------MAYSTVQRVALASGLVLALSLLLPKAFLSRGKRQEPPPTPEGKLGRFPPMMHHHQAPSDGQTPGARFQRSHLAEAFAKAKGSGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLS-KGKTTAEDGKCYTAMPGNTHRKITSFELAQLQEKLKETEAAMEKLINRVGPNGESRAQTVTSDQEKRLLHQLREITRVMKEGKFIDRFSPEKEAEEAPYMEDWEGYPEETYPIYDLSDCIKRRQETILVDYPDPKELSAEEIAERMGMIEEEESDHLGWESLPTDPRAQEDNSVTSCD---------------------------------------------------------------PKPETCSCCFHEDEDPAVLAEN---------AGFSADSYPEQEETTKEEWSQDFKDEGLG---------------------------------------------------ISTDKAYTGSMLRKRNPQGLE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1Q8-1", "uniprot_id": "A0A8M6Z1Q8_DANRE", "id": "A0A8M6Z1Q8-1", "name": "", "aln": "MFSVISASSGQKRCRDVDVRHRLLCGVFSLSAIDMAISTCQKITFVSCLVLCMSLFLPRLFLPRVKKEAVRSDVGPGHLPPSRHIHSLSEDHDHWDTDSHYIKHYSPDAIASFKGVKK--------PNLLGQVIPVYGFGIFLYIIYLFVKLTSKDKPHRQGCRFPLLQSQYTFEEMPTCQLVQLQARMSEKAR--EKRISKVVHP-SARSRRGTRRREERKLKQLKEISQMMRERQLREGATPEEEAEEAPYNADWEGYPDETYPEYKIPS-RRRRYPSVILEEPDQVILTAEELAERMEKEEEVEEEETADDTCANEELNLEDNEEDEEDEEQEEEDEEEEEDEEEDIAEDQPCLPQSFDEDDEGLEYSDEREEKPSRRRQITFSDHRHVFHYPKGGAVGCKYETEEEEEHEGEEEEEGNEEDENGESEECEEEEEEEEEEEEEEQHDKEEHGEREEKEEEDPLMEAESLGFNDDVECDPDEQEVDLIDFLQTYQPEVTVISNKSESSKRQASGTLRMRHKKEKVKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ** *::::.* ***.:**:**: **.* *: . . :* * ..::: : : .:*:*. ** .*:**:**:*********:*::.**: *.* :. . . :..::.. :*.*** ::.*. ** *.:* .:*:: * :*:* *:**:**:::*:* :: : :**:******* ******:**** *.:.. :** ::::: ** :*** **:* :* .:. . : ..: .**. * ** : .* . :*: .*: * * : *:** :*: ::. .* * .:.: ... ** * : ", "identical_positions": 112, "similar_positions": 118, "identity": "21.17%" }, { "cls_id": "homologset.agr.MGI:2443893", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ANF0-1", "uniprot_id": "A0A8I6ANF0_RAT", "id": "A0A8I6ANF0-1", "name": "", "aln": "MAEPEDQADGSNLEGEQTSAEEETEQQYTEGHEVSPQLENSGQKTAEGREPTQDPERGITTDSEGRLEGEMVDAERVSTEGEAISEGEVGSIGEAFPETEVEFIGEAPPDTVVEFIGEAPPGTEVEFIGETTPETQAEPTGEATPGVAVKTIRK--AEQEVEVIREVISETDVDSIVKAIQGVDLESIGATIPQKKVKYTAKARPQDEAEPTGEPAPEGDFDVSEQEKAG-HPSELDELSDIISSPAFSYSDVSPWDMGEEEAKA-LTTQDISQESVYEPIELIQPTEPTEP---------PEDSVVRPIEPSRQRSFPMGARHRFRLSIMGSLTPSDIDDLPLETEEALQQESVQPPPRAHEETRIQFLDQVQTLSLEDETQIERPMSEGSDE-AEEEGAQLMVLDPDHPLMVRFQEALKSYLNRQIDKLKLDIQELDVATKQTRIQRQELGVNLYGVQQHLARLQMQLEKSHDRHSLVACERRRKEEELQCNRALYNKTYATAKEERKKFAALQTEMESLALHLFYMQNIDQDVRDDIQVMKQVVKKTETEKMNAEIEKKKQDLFVDQLTERAHQLEENIALYEAQYLSQAEDTRVLRKAVTEAITEIDTIIMEKKRILQQWTTSLVGMKHRNEAYRTVMDALRECEHQVKSIDSEIEAYKKSIMQEEEKNEKLARLLNRAETEAALVQKMTTQCLSKQETLQTEFNTYQLALQDTEEMLNKGYVEHSAVLSELQGTRQAVHQEQELRQKMDISIMDKLQEHGTSSKMTKYFHQLLRKLQKENTNLVTHLSKIDGDIAQATLDITNTNGKVEMHKKTLLDLDKEVKRFNELITNSESEIVRRTILIERKQSLINFFNKQLEQMVSVLGGEEAGPLELEIKRLSKLTEEYNTGVTQAQMTWLRLQQELVQISHEREERLESVDQLKKEVHIMEQKKLRIENKIEHEKREQKMVSRHMRDLDNDLSKLNMLLDKNRCSSELLEQNNAVAETEFVRTLKDAERETIQMQEKLSELCEEKATLLNSLVEAEHQIMLWEKKIQLAKEMRSSVDSDTGQT-EIRAMKAEIHRMRVKHGQLLKQQEKMIRDMELAVARRETIVIQAEGQSK-IDKKIVTKSDFHFQQ---SELRKKIREVHKATEECSKTVLELEEAQKLLSSSLQEKQQSLSDMQSDTDVLEEEISHLSALKRKNLLEIVALQTRAKHLQAAVDGK-YVFLHRNSKAQLMERKRLGMKLSQLSSVLSRVQEDYPQYQEMLQKIQEKIATRLEAPEPS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BI79-1", "uniprot_id": "CCD40_MOUSE", "id": "Q8BI79-1", "name": "Coiled-coil domain-containing protein 40", "aln": "----------------------------------------------------------------------MMDAEKVSTDGEAISEGEVGSNGETPPETEVEFIGETAPDTDVEFIGETSPGTDVEPTGESIQETEVESIGEATPGMDVEPIKKTMTELNVESIGEETSETDVDSIRKALRGIDLESITVAYPPKKAKHR-KVRPQAEVESTGRAAPEGELEVSDHEKVEALLDELDELSEIVSSPEVSYSDISPLEMGEDDTNVSATSTDTFQQGIYEPIEPIEPTEPPEPAEPPKPAETPEDSTVRAPAHPYQRDFPMGARHRFRLSIMGSLTPSDTDDLPLETDEPPQQESVQSTPRALEETRIQFLDQVQSLS--PEALLDR-ATEGSDE-AEEEGSQLIVLDPDHPLMIRFQEALKGYLNRQMDKLKLDVQELDVATKQTRSQRQELGVNLYGVQQHLARLQMQLEKSHDRHSLVACERRRKEEELQCARSVYNKTCQTANEERKKLAALQTEVESLALHLFYMQNIEQDVRDDIQVMKQVVRKTETEKMHAEVEKKKQDLFVDQLTERSHQLEENIALFEAQYLSQAEDTRVLKKAVTEAITEIDTIAVEKKRILQQWTTSLVGMKHRNEAYKTVMDALRECQHQVKSTDSEIEVCKKSIMQEEEKNEKLARLLNRAETEATLVQKMTAQCLSKQEALQTEFNTYQLALQDTEEMLNKGYVEHSAVLSELQATRQAFHQEQELRQKMDMSMVDKLQEQGTSSKMTKYFHQLLRKLQKENTNLVTHLSKIDGDIAQATLDITNTNCKIDMHKKTLAEMDKEVKRFNDLITNSESEIARRTILIERKQSLINFFNKQLEQMVSELGGEEAGPLELEIKRLSKLTEEYNTGVAEAQMTWLRLQQELVQVTHEREEQLVSVDQLKKEVHIMEQKKLRIESKIAHEKKEQKIVSRHMRDLDNDLSKLNMLLDKNRCSSEELEQNNIATETEFLRTLKDSERETIQMQEKLMELSEEKATLLNSFMEAEHQIMLWEKKIQLAKEMRSSVDSETGQT-EIRAMKAEIHRMKVRHGQLLKQQEKMIRDMELAVARRETIVVQAEGQSK-IDKKVITKTEFHYQQ---RELQKKVREMHKATDDCTNTISELEETQKFLSSSLQEKQQLLSEMQATTDVLEEEINQLTALKRQNLLEIVTLQTRGKHLQAAIEGK-YVFLHRNSRSQLMERKRLSVRLSQLNKVLSSVQEDYPQYQEVLQSIQQKIATKLETPEPS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G0X9-1", "uniprot_id": "CCD40_HUMAN", "id": "Q4G0X9-1", "name": "Coiled-coil domain-containing protein 40", "aln": "------------------------------------------------------------------------MAEPGGAAGRSHPEDGSASEGEKEGNNESHMV--SPPEKDDGQKGEEAVGSTEHPEEVTTQAEAAIEEGEVET----------EGEAAVEGEEEAVSYGDAE------------------SEEEYYYTETSSPEGQISAADTTYP---YFSPPQELPG------EEAYDSVSG-EAGLQGFQQEATGPPESRERRVTSPEPSHGVLGPSEQMGQVTSG-P---------AVGRLTGSTEEPQGQVLPMGVQHRFRLSHGSDIESSDLEEFVSQEPVIPPG---VPDAHPREGDLPVFQDQIQQPSTEEGAMAERVESEGSDEEAEDEGSQLVVLDPDHPLMVRFQAALKNYLNRQIEKLKLDLQELVVATKQSRAQRQELGVNLYEVQQHLVHLQKLLEKSHDRHAMASSERRQKEEELQAARALYTKTCAAANEERKKLAALQTEMENLALHLFYMQNIDQDMRDDIRVMTQVVKKAETERIRAEIEKKKQDLYVDQLTTRAQQLEEDIALFEAQYLAQAEDTRILRKAVSEACTEIDAISVEKRRIMQQWASSLVGMKHRDEAHRAVLEALRGCQHQAKSTDGEIEAYKKSIMKEEEKNEKLASILNRTETEATLLQKLTTQCLTKQVALQSQFNTYRLTLQDTEDALSQDQLEQMILTEELQAIRQAIQGELELRRKTDAAIREKLQEHMTSNKTTKYFNQLILRLQKEKTNMMTHLSKINGDIAQTTLDITHTSSRLDAHQKTLVELDQDVKKVNELITNSQSEISRRTILIERKQGLINFLNKQLERMVSELGGEEVGPLELEIKRLSKLIDEHDGKAVQAQVTWLRLQQEMVKVTQEQEEQLASLDASKKELHIMEQKKLRVESKIEQEKKEQKEIEHHMKDLDNDLKKLNMLMNKNRCSSEELEQNNRVTENEFVRSLKASERETIKMQDKLNQLSEEKATLLNQLVEAEHQIMLWEKKIQLAKEMRSSVDSEIGQT-EIRAMKGEIHRMKVRLGQLLKQQEKMIRAMELAVARRETVTTQAEGQRK-MDRKALTRTDFHHKQ---LELRRKIRDVRKATDECTKTVLELEETQRNVSSSLLEKQEKLSVIQADFDTLEADLTRLGALKRQNLSEIVALQTRLKHLQAVKEGR-YVFLFRSKQSLVLERQRLDKRLALIATILDRVRDEYPQFQEALHKVSQMIANKLESPGPS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q56A40-1", "uniprot_id": "CCD40_DANRE", "id": "Q56A40-1", "name": "Coiled-coil domain-containing protein 40", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGRQEDQMNRQEEVEQSNNYDRSVDHAR--------TGRSSWIDNSEINSKWIPQHS--LQLEMNNIEGEGSVRENDEEEEEIVVLDPEHPLMKRFQTALKNNFTNQLERLNLDLCEKVVVEKAEAQRRHDLAEEVYMVQEMLARLQASLEVCQETNSEAAAQHRQAEDHLYVVKNQYQDTASQTNVQRLQVLELQSKVDNLALKLLYMQEAKSDLCSDIKAIINASNKAQKERTQTEEQKHQQDIYVERLTNRVEKLLEQISLYDLQLISQTEQTRAAKDSLSEAQLELDSVIVEHRQLLQQWKSSLLMMKRRDEAYTAMQEELRQANDQMLSLDTEIESYKKSITQEEEQNECLTLRLNRGQTDCTTSRKLITHSQNLQEVLQAQLSTYTRILQETENTLSTLHGNLEMHQSALKALRKQMEKVSAVRLDLESQIMNKLQEQLTHNNAAKYSRRMNDKTAVYRREKEAQLIKFENDFNTVTLEGQELATHLDSLLAFQAELEQKSTQRHLLLSSREEEIVKQITDIERKQATISIYNKKIKDIVSSTGHEDLGPLEIHAATLSKELEEVGAKIKECQQLWLWQQGELVRFTQEKQAHSSSVQILQTQLTILQQGKIRRESEMEQDQSELADLDKQIKVLMADMVKLNSLLNKNSDLNHALQQSSNLMETEFRQRLKEAEKDSAETQLKLERLNEEKERLINSLVEAERQVMLWGKRTQLMQETCSAIDSDIGQG-DIRTMRAEIHRMEVRYAQLMKQQERLLRDMESVVAKSKTIAVWSEAQARTQAHKQPTHNDYHNTI---QSLRRKILQTKKQTEECDGVIAQLEERLGSMTSRLQDKQMHLNNIQNTEAFLSQDLRRLQEIKERNLYRLPVLQTRAKHLHAVKEGR-YTPMATGVTALELGTHKQEERLKMVSLTLQRLAQEYPQHHSTLHRMNSILAEHLHGECPNSQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B7P7M6-1", "uniprot_id": "A0A0B7P7M6_DROME", "id": "A0A0B7P7M6-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDPEDIDCDFPISFEPNPEASPEPEELALLPPNHPLLSKFQVCLKGHLIRTKREIENEIAEIKHHVKLREQRREEQGLTLYDMQQKMKFQEKQIMELSAVIEKHLKNRQDEEFNTKTLKAENEEKIKLTKSQKTLYHERMAELGDMQSLGSNIKKWACSVEDEVKNAKRIVSRDAQLQDQLSQEKRKSDILFYRLDIEIKKRENELLSICEEEATMKEVINILNMSIANANTDLEVLQNEHKRLTQAWNEVIIAIQLRDKILFQVQDAARKHREAMKHNIAGIEAIKKQIGKEMELNKKLDSFKQRLADETSSLRRECQDESESLLKMQAKLDDLPEFLNTTETDLQDALREGSHLFTEVRKLDIALDKYLTQKFRTEETILRLAQDHLITDKATAYRLKLLGKSQEKRRNVDLSLSKVQNQLSLSMLEVEKLRCVVFNERAYNDSTKTKLKSAENKSSTLENGLKKIHIQIEIKMKLYEKINCKIEEMDHLFGDASGNPTDLKIKQLEKSIHIGELQVREHQQFWIMLQNHFVNLSQKRNDQLNEIQVTRKQLSIIRQKSLKSDQELEISHRKAKELQIFIKKFTSKLELLNDKIYKKRIHHDVEETEFDHEQAEQTQKLKIAELEILKLEGKIVELQNEIELHKDYVIDKHRETLSWETKYKMIEETIKWAKLERSVKGEIGLMKTEIHRMNIRYSQLKRAQESLVLDLEHCVMHREQIFVNASVKEHLQAKFKQLKNTSQIQVRLDEVHNRTKLISNEITFLSEKQLIDDINKIERMIYMLRRIQSDLNDIIKEDANIQDRIEEGILAKHANLEQIIRKQMRAKAYKRLNTLKSQQVILRSELTVQQLSQKQSELNYDLTEIAKALLLDYPKKKSYVFKVLHVLND----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . . * :: :* *:***: :** .**. : . .:: :: * * :*.: . :* :*: : : : ::: * . : .. :: :: ::: .: ::: .: .::: . : : . . :*::.*: . :* . .: ::: : : * . . ::::* ::: : *:::: * * :: :: *:: : : * .. ** **.* :* * *: * :* : : :: . :*:::. *: ** *. : :: .. : : : *:: .: : * :: : . : * *.:.:: *: . : . . . . . :. :. : : ** * . * ::: : * . .* ::. *.* . : * *: * .:*..::::: : .:: :.:: *:.* .:: :.:: .: : :. :: : .: ** : *: . : . : * : ** :* : : : *: .* :* : .:: .:: : * .: :: :* . . : . :* *: *****.:: .** : ** :: :* * : : : :. : : : :. : .:. .: * . : : : : * * *. : :. : . *. ** .: * * * : : : . : :: : . : :**: :. : : : ", "identical_positions": 98, "similar_positions": 288, "identity": "7.69%" }, { "cls_id": "homologset.agr.MGI:2443895", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G1L6-1", "uniprot_id": "A0A8I6G1L6_RAT", "id": "A0A8I6G1L6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MAS-----------------------------QQDSGFFEISIKYLLKSWS---------NASPVGNGYIKPPVPP--------------------------------ASGTHRE-KGPPAMLPINVDPDSKPGEYVLKSVFVSFTTQAERKIRIIMAEPLEKPLTKSLQRGEDPQFDQVISSMSSLSEY-----CLPSILRTLFDWYKRQN-GMEDESHEYRPRTSNKSKSDEQQR-----------DYLMERRDLAIDFIFSLVLIEVLKQIPLHPVIDGLVHDIINLAFKHFKYKEGYLG-PNTGNMHIVADLYAEVIGVLAQAKFPAVKKKFMAELKELRQKEQSPYVVQSIISLIMGVKFFRIKMYPVEDFEASLQFMQECAHYFLEVKDKDIKHALAGLFVEILVPVAATVKNEVNVPCLRNFVESLYDTTLELSSRKKHSLALYPLVTCLLCVSQKQLFLNRWHVFLNNCLSNLKNKDPKMARVALESLYRLLWVYMIRIKCESNTATQSRLITITTTLFPKGSRGVVPRDMPLN-IFVKIIQFIAQERLDFAMKEIIFDFLCVGKPAKAFS-LNPERMNIGLRAFLVIADSLQQKDGEPPMPVTGAVLPSGNTLRVKKTY--LSKTLTEEEAKMIGMSLYYSQVRKAVGNILRHLDKEVGRCMMLTNVQMLNKEPEDMITGERKPKIDLFRTCVAAIPRLLPDG--VSKVELIDLLARLSIHMDDELRHIAQNSLQGLLVDFSDWREEVLFGFTNFLLREVNDVHHTLLDSSLKLLLQLLTQWKLVIQTQGRVYEQA--------------------------------------------KIRNSELIPNGS-GHRMQSER----------------------GPHCSVLHAVEGFALVLLCSFQMATRKLSVLILKEIRALFLALGQPEDDDRPMIDVMDQLSSSILES-FIHVAVSDSATLPPTHNVDLQWLVEWN-AVLVN--SHYDVKSPSHVWIFAQS----------------VKDPWVLCLFSFLRQENLPKHCPTALSYAWPYAFTRLQSVMPLVDPN-----------SPVNAKKTSTASSGDNYVTLWRNYLILCFGVAKPSIMSPGHLRASTPEIMATTPDGTVS--YDNKAIGTPSVGVLLKQLVPLMRLESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADASVISDSTNGALERDTLALGALFLEYVDLTRMLLEAENDKEVEILKDIRAHFSAMVANLIQCVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVMLLLELNPDQINLFNWAIDRCYTGSYQLASGCFKAIATVCGNRNYPFDIVT-LLNLVLFKASDTNREIYEVSMQLMQILKAKLF---LHSKKAAEQRPGSVLYGTHGPLPPLYSVSLALLSRELARMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLHNIELVDSRLLLPGSSPSSPEDEVKDREGEVTASHGLKGKGWGSPEATSLVLNNLMYMTAKYGDEVPGAEMENAWNALANNEKWSNNLRVTLQFLISLCGVSSDTILLPYIKKVAIYLCRNNTIQTMEELLFELQQTEPVNPIVQHCDNPPFYRFTASSKATAAASGTTSSS--------------NTVVAGQDSFPDPEESKILKESDDRFSNVIRAHTRLESRYSNSSGGSYDEDKNDPISPYTG---------WLLSITEAKQ-----------------PQPLPMPCTGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLHAVFLGLDHYRPEVFEHSKKLLLHLLIALSCNSNFHAIASVLLQTREMGEVKTLTMQPAYQPEYLYTGGFDFLR-------EDQSSPVPDSGLSSS---------------STSSSISLGGSSGNLPQMTQEVEDVD-AAAESDEK------------------------ANKLIEFLTT----------RAFGPLWCHEDITPKNQNSKSAEQLSNFLRHVVSVFKDSKSGLHLEQHLSEVALQTALASSSRHYAGRSFQIFRALKQPLSAHALSDLLSRLVEVIGEHGDEIQGYVMEALLTLEAAVDNLSDCLKNSDLFTVLSRSSS--------PDLSSSSKLTASRKSTGQLNVSPGTP--------SGSTATAERSRHQRSFSVPKKFG--VVDRSSDPPRSATLDR-IQACTQQGLSSKTRSSSS-----LKESLTDPSHVNHPTNLLATIFWVTVALMESDFEFEYLMALRLLNRLLAQMPLEKAENREKLEKLQAQLKWADFPGLQQLLLKGFTSLTTTDLTLQLFSLLTPVSRVPMVDSSQAIGFPLNVLCLLPQLIQHFENPNQFCKGIAERIAQVCLEEK--NPKLSNLAHVMTLYKTHSYTRDCATWVNVVCRYLHEAYADITLNMVTYLAELLEKGLPSMQQPLLQVIYCLLSYMDLSVVPGKQFNMEVLKTIEKYVQSIHWREALNILKLVVSRSASLVLPSYQHSDLSKIELHR--VWTSA----SKELPGKTLDFHFDISETPIIGRR------------YDELQNSSGRDGKPR-AMAVTRS----------------------------------------ASSTSSGS-NSN---------VLVPVS-WKRPQYSQKRTKEKLVHVLSLCGQEVGLSKNPSVIFSSCGDLDLPEHQTSLVSSEDGTREQENMDDANS-----EQQFRVFRDFDFLDVELEDGEGESMDNFNWGVRRRSLDSLDKCDMQTLEE-RQLSRSTPSLNK-------MSHEDSDESSEE-DLTASQILEHSDLIMNLSPSEEANPMELLTSACDSTPADPHPFNARITNFEASLPDINNLQISEGSKAEVVPEEEDTTVHEDDLSSSINELPATFECSDSFSLDMTEAEE---------KGNRGLDQYTLASFGEGDR-------GVSPPPSPFFSAILAAFQPVSCDDAEEAWRSHINQLMCDSDGSCAVYTFHVFSSLFKNIQKRFCFLTCDAASYLGDNLRGIGSKFVSSSQMLTSCSECPTLFVDAETLLSCGLLDKLKFSVLELQEYLDTYNNRKEATLSWLANCKATFAG--------------SSRDEVITCQPGDSEEK------QLELCQRLYKLHFQLLLLYQSYCKLIG-QVHEVSSVPELLNMSRELSDLKRKLKEATAAISTD-PLYIEGAWSEPTFTST-------EAAIQSMLECLKNNDLGKALRQIKECRSLWPN--------DIFGSSSDD------EVQTLLNIYFRHQTLGQTGTYALVGSNHSLTEICTKLMELNMEIRDMIRRAQSSRVLTTFLPDSSVSGTSL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q8I9-1", "uniprot_id": "FRY_MOUSE", "id": "E9Q8I9-1", "name": "Protein furry homolog", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MAS-----------------------------QQDSGFFEISIKYLLKSWS---------NASPVGNGYIKPPVPP--------------------------------ASGTHRE-KGPPAMLPINVDPDSKPGEYVLKSLFVNFTTQAERKIRIIMAEPLEKPLTKSLQRGEDPQFDQVISSMSSLSEY-----CLPSILRTLFDWYKRQN-GIEDESHEYRPRTSNKSKSDEQQR-----------DYLMERRDLAIDFIFSLVLIEVLKQIPLHPVIDSLIHDIINLAFKHFKYKEGYLG-PNTGNMHIVADLYAEVIGVLAQAKFPAVKKKFMAELKELRHKEQSPYVVQSIISLIMGMKFFRIKMYPVEDFEASLQFMQECAHYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLELSSRKKHSLALYPLVTCLLCVSQKQLFLNRWHVFLNNCLSNLKNKDPKMARVALESLYRLLWVYMIRIKCESNTATQSRLITITTTLFPKGSRGVVPRDMPLN-IFVKIIQFIAQERLDFAMKEIIFDFLCVGKPAKAFS-LNPERMNIGLRAFLVIADSLQQKDGEPPMPVTGAVLPSGNTLRVKKTY--LSKTLTEEEAKMIGMSLYYSQVRKAVGNILRHLDKEVGRCMMLTNVQMLNKEPEDMITGERKPKIDLFRTCVAAIPRLLPDG--MSKLELIDLLARLSIHMDDELRHIAQNSLQGLLVDFSDWREDVLFGFTNFLLREVNDMHHTLLDSSLKLLLQLLTQWKLVIQTQGRAYEQAN-------------------------------------------KIRNSELIPNGS-SHRMQSER----------------------GPHCSVLHAVEGFALVLLCSFQVATRKLSVLILKEIRALFLALGQPEDDDRPMIDVMDQLSSSILES-FIHVAVSDSATLPPTHNVDLQWLVEWN-AVLVN--SHYDVKSPSHVWIFAQS----------------VKDPWVLCLFSFLRQENLPKHCPTALSYAWPYAFTRLQSVMPLVDPN-----------SPVNAKKTSTASSGDNYVTLWRNYLILCFGVAKPSIMSPGHLRASTPEIMATTPDGTVS--YDNKAIGTPSVGVLLKQLVPLMRLESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAENDKEVEILKDIRAHFSAMVANLIQCVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVMLLLELNPDQINLFNWAIDRCYTGSYQLASGCFKAIATVCGNRNYPFDIVT-LLNLVLFKASDTNREIYEVSMQLMQILEAKLF---VHSKKVAEQRPGSILYGTHGPLPPLYSVSLALLSCELARMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLHNIELVDSRLLLPGSSPSSPEDEVKDREGEVTASHGLKGNGWGSPEATSLVLNNLMYMTAKYGDEVPGAEMENAWNALANNEKWSNNLRVTLQFLISLCGVSSDTILLPYIKKVATYLCRNNTIQTMEELLFELQQTEPVNPIVQHCDNPPFYRFTASSKASAAASGTTSSS--------------NTVVAGQDSFPDPEESKILKESDDRFSNVIRAHTRLESRYSNSSGGSYDEDKNDPISPYTG---------WLLSITEAKQ-----------------PQPLPMPCSGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLHAVFLGLDHYRPEVFEHSKKLLLHLLIALSCNSNFHAIASVLLQTREMGEAKTLTMQPAYQPEYLYTGGFDFLR-------EDQSSPVPDSGLNSS---------------STSSSISLGGSSGNLPQMTQEVEDVE-AATETDEK------------------------ASKLIEFLTT----------RAFGPLWCHEDITPKNQNSKSAEQLSNFLRHVVSVFKDSRSGFHLEQHLSEVALQTALASSSRHYAGRSFQIFRALKQPLSAHALSDLLSRLVEVIGEHGDEIQGYVMEALLTLEAAVDNLSDCLKNSDLFTVLSRSSS--------PDLSSSSKLTASRKSTGQLNVNPGTPGSGGGGGGSGNTTTAERSRHQRSFSVPKKFG--VVDRSSDPPRSATLDR-IQACTQQGLSSKTRSNSS-----LKESLTDPSHVSHPTNLLATIFWVTVALMESDFEFEYLMALRLLNRLLAHMPLEKAENREKLEKLQAQLKWADFPGLQQLLLKGFTSLTTTDLTLQLFSLLTSVSKVPMVDSSQAIGFPLNVLCLLPQLIQHFENPNQFCKDIAERIAQVCLEEK--NPKLSNLAHVMTLYKTHSYTRDCATWVNVVCRYLHEAYADITLNMVTYLAELLEKGLPSMQQPLLQVIYSLLSYMDLSVVPVKQFNMEVLKTIEKYVQSIHWREALNILKLVVSRSASLVLPSYQHSDLSKIELHR--VWTSA----SKELPGKTLDFHFDISETPIIGRR------------YDELQNSSGRDGKPR-AMAVTRS----------------------------------------ASSTSSGS-NSN---------VLVPVS-WKRPQYSQKRTKEKLVHVLSLCGQEVGLSKNPSVIFSSCGDLDLPEHQTSLVSSEDGPREQENMDDTNS-----EQQFRVFRDFDFLDVELEDGEGESMDNFNWGVRRRSLDSLDKCDMQILEE-RQLSRSTPSLNK-------MSHEDSDESSEE-DLTASQILEHSDLIMNLSPSEEANPMELLTSACDSAPADPHSFNTRMANFEASLPDINNLQISEGSKAEAVPEEEDTTVHEDDLSSSINELPAAFECSDSFSLDMTEAEE---------KGNRGLDQYTLASFGEGDR-------GVSPPPSPFFSAILAAFQPAACDDAEEAWRSHINQLMCDSDGSCAVYTFHVFSSLFKNIQKRFCFLTCDAASYLGDNLRGIGSKFVSSSQMLTSCSECPTLFVDAETLLSCGLLDKLKFSVLELQEYLDTYNNRKEATLSWLANCKATFAG--------------GSRDGVITCQPGDSEEK------QLELCQRLYKLHFQLLLLYQSYCKLIG-QVHEVSSVPELLNMSRELSDLKRNLKEATAAIATD-PLYIEGAWSEPTFTST-------EAAIQSMLECLKNNELGKALRQIKECRSLWPN--------DIFGSSSDD------EVQTLLNIYFRHQTLGQTGTYALVGSNHSLTEICTKLMELNMEIRDMIRRAQNYRVLTAFLPDSSVSGTSL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TBA9-1", "uniprot_id": "FRY_HUMAN", "id": "Q5TBA9-1", "name": "Protein furry homolog", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MAS-----------------------------QQDSGFFEISIKYLLKSWS---------NTSPVGNGYIKPPVPP--------------------------------ASGTHRE-KGPPTMLPINVDPDSKPGEYVLKSLFVNFTTQAERKIRIIMAEPLEKPLTKSLQRGEDPQFDQVISSMSSLSEY-----CLPSILRTLFDWYKRQN-GIEDESHEYRPRTSNKSKSDEQQR-----------DYLMERRDLAIDFIFSLVLIEVLKQIPLHPVIDSLIHDVINLAFKHFKYKEGYLG-PNTGNMHIVADLYAEVIGVLAQAKFPAVKKKFMAELKELRHKEQNPYVVQSIISLIMGMKFFRIKMYPVEDFEASLQFMQECAHYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLELSSRKKHSLALYPLVTCLLCVSQKQLFLNRWHIFLNNCLSNLKNKDPKMARVALESLYRLLWVYMIRIKCESNTATQSRLITIITTLFPKGSRGVVPRDMPLN-IFVKIIQFIAQERLDFAMKEIIFDFLCVGKPAKAFS-LNPERMNIGLRAFLVIADSLQQKDGEPPMPVTGAVLPSGNTLRVKKTY--LSKTLTEEEAKMIGMSLYYSQVRKAVDNILRHLDKEVGRCMMLTNVQMLNKEPEDMITGERKPKIDLFRTCVAAIPRLLPDG--MSKLELIDLLARLSIHMDDELRHIAQNSLQGLLVDFSDWREDVLFGFTNFLLREVNDMHHTLLDSSLKLLLQLLTQWKLVIQTQGKVYEQAN-------------------------------------------KIRNSELIANGS-SHRIQSER----------------------GPHCSVLHAVEGFALVLLCSFQVATRKLSVLILKEIRALFIALGQPEDDDRPMIDVMDQLSSSILES-FIHVAVSDSATLPLTHNVDLQWLVEWN-AVLVN--SHYDVKSPSHVWIFAQS----------------VKDPWVLCLFSFLRQENLPKHCPTALSYAWPYAFTRLQSVMPLVDPN-----------SPINAKKTSTAGSGDNYVTLWRNYLILCFGVAKPSIMSPGHLRASTPEIMATTPDGTVS--YDNKAIGTPSVGVLLKQLVPLMRLESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAENDKEVEILKDIRAHFSAMVANLIQCVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQINLFNWAIDRCYTGSYQLASGCFKAIATVCGSRNYPFDIVT-LLNLVLFKASDTNREIYEISMQLMQILEAKLF---VYSKKVAEQRPGSILYGTHGPLPPLYSVSLALLSCELARMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLHNIELVDSRLLLPGSSPSSPEDEVKDREGDVTASHGLRGNGWGSPEATSLVLNNLMYMTAKYGDEVPGPEMENAWNALANNEKWSNNLRITLQFLISLCGVSSDTVLLPYIKKVAIYLCRNNTIQTMEELLFELQQTEPVNPIVQHCDNPPFYRFTASSKASAAASGTTSSS--------------NTVVAGQENFPDAEENKILKESDERFSNVIRAHTRLESRYSNSSGGSYDEDKNDPISPYTG---------WLLTITETKQ-----------------PQPLPMPCTGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLHAVFLGLDHYRPEVFEHSKKLLLHLLIALSCNSNFHSIASVLLQTREMGEAKTLTVQPAYQPEYLYTGGFDFLR-------EDQSSPVPDSGLSSS---------------STSSSISLGGSSGNLPQMTQEVEDVD-TAAETDEK------------------------ANKLIEFLTT----------RAFGPLWCHEDITPKNQNSKSAEQLTNFLRHVVSVFKDSKSGFHLEHQLSEVALQTALASSSRHYAGRSFQIFRALKQPLSAHALSDLLSRLVEVIGEHGDEIQGYVMEALLTLEAAVDNLSDCLKNSDLLTVLSRSSS--------PDLSSSSKLTASRKSTGQLNMNPGTT--------SGNTATAERSRHQRSFSVPKKFG--VIDRSSDPPRSATLDR-IQACTQQGLSSKTRSSSS-----LKDSLTDPSHINHPTNLLATIFWVTVALMESDFEFEYLMALRLLSRLLAHMPLDKAENREKLEKLQAQLKWADFSGLQQLLLKGFTSLTTTDLTLQLFSLLTPVSKISMVDASHAIGFPLNVLCLLPQLIQHFENPNQFCKDIAERIAQVCLEEK--NPKLSNLAHVMTLYKTHSYTRDCATWVNVVCRYLHEAYADITLNMVTYLAELLEKGLPSVQQPLLQVIYSLLSYMDLSVVPVKQFNVEVLKTIEKYVQSVHWREALNILKLVVSRSASLVLPSYQHSDLSKIEIHR--VWTSA----SKELPGKTLDFHFDISETPIIGRR------------YDELQNSSGRDGKPR-AMAVTRS----------------------------------------TSSTSSGS-NSN---------VLVPVS-WKRPQYSQKRTKEKLVHVLSLCGQEVGLSKNPSVIFSSCGDLDLLEHQTSLVSSEDGAREQENMDDTNS-----EQQFRVFRDFDFLDVELEDGEGESMDNFNWGVRRRSLDSLDKCDMQILEE-RQLSGSTPSLNK-------MHHEDSDESSEEEDLTASQILEHSDLIMTLSPSEETNPMELLTTACDSTPAEPHSFNTRMSSFDASLPDMNNLQISEGSKAEAVREEEDTTVHEDDLSSSINELPAAFECSDSFSLDMTEGEE---------KGNRALDQFTLASFGEGDR-------GVSPPPSPFFSAILAAFQPAACDDAEEAWRSHINQLMCDSDGSCAVYTFHVFSSLFKNIQKRFCFLTCDAASYLGDNLRGIGSKFVSSSQMLTSCSECPTLFVDAETLLSCGLLDKLKFSVLELQEYLDTYNNRKEATLSWLANCKATFAG--------------GSRDGVITCQPGDSEEK------QLELCQRLYKLHFQLLLLFQSYCKLIG-QVHEVSSMPELLNMSRELSDLKKHLKEASAVIAAD-PLYSDGAWSEPTFTST-------EAAIQSMLECLKNNELGKALRQIRECRSLWPN--------DIFGSSSDD------EVQTLLNIYFRHQTLGQTGTYALVGSNQSLTEICTKLMELNMEIRDMIRRAQSYRVLTTFLPDSSVSGTSL-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TIX3-1", "uniprot_id": "A0AB32TIX3_DANRE", "id": "A0AB32TIX3-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------MSVKDVGSAGVVVDSKLDPCETQSRDGIVLVQMAS-----------------------------LSMHMFAPADFKGKFRKIQPRKRPTIIKEASPIG----KRPLPQ--------------------------------VSSALGERKGPVATMPVTVDPESKPGEYVLKSLFANFTTLSERKIRIIMAEPLEKPLTKSLQRGEDPQFDQLISTMSSLAEY-----CLPSILRTLFDWYKRQN-GLEDESHEYRPRANTKSKNDEQQK-----------DYLMERRDLAIDFIFSLVLIEVLKQIPLHPLLDGLIQEVINLAFKHFKYKEGYLG-PNTTNMHIVADLYAEVVGVVAQSRFPAVRKKFISELKELRQKEQSPYVVQSTISLIMGVKFFRIKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHSLAGLFVEILVPVAATVKNEVNVPCLRNFVETLYDTTLDLSSRKKHSQALYPLVTCLLCVSQKQIFLNRWHVFLNNCLSNLKNKDHKMARVALESLYRLLWVYMIRIKCESNTATQSRLTSIISTLFPKGSRSVVPRDMPLN-IFVKIIQFIAQERLDFAMKEIICDLLSVGKSAKAFS-LNPERMNIALRAFLVIADNLQQKDGEPPMPNTGATLPSGNTLKKKKTY--LSKTLTEEEAKLIGMALYYSQVRKAMDNILRHLDKEVGRCMMLTNAQMLNKEPEDMITGERKPKIDLFRTCVAAIPRILPDG--LSKIELIDLLARLTVHMDDELRLIAQNSLQSLLLDFSDWREDVLFGYTNFLLREVQDTQQGLQDSSVKLLLHFLTQWRLAIQAPGK---------------------------------------------------RSAEMGSQSSGSSRLAPDR----------------------SPHSTVLHAVEGLALLLLCSCQTSTRKLAVSVLREIRLLFTAIGQAEDDDKSMIEVMDQLAPSVLDS-FVHVAVSDSATLPLSHHVDLQWLVEWN-ARLVN--SHYDVKSPSHVWIFAQS----------------VKDPWVLCLYSFLRPEHLPKHCPTALSYAWPYAFTRLQLLMPLVDPN-----------SPVYAKKTSTPGSADGYVTLWRNYLIMCLGVAKPSIMSPGHLRASTPEIMATTPDGSVT--YDNKVIGTPSVAWLLKQLVPLMRSESLEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADSGVISDSTNGALERDSLALGALFLEYVDLTRMLLEAENDKELDILKDMRAHFSGMVANLIQCVPVHNRRLLFPQQSLRHHLFILFSQWAGPFSVMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSTDGYLYKWLDNILACHDLRVHRLGCEVVILLLELNPDQVNLFNWAVDRCFTGSYQLASGCFKAIATVCGSRNYPCDIVT-LLNLVLFKSSDTSREIYEISMQLMQVLESKLS---VYSKRTVGQKSGSILYGTHGPLPPLYSVSLFQLSNQLACMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLNNIELVDTGLLPPASSPCTPEEEAREQADNLGITHRLKGNGWGSLQATSLVLNNLMFMTAKYGDEVPGPEMENAWNALVSNDKWSNNLRITLQFLISLCGVSSDTTLLPYIKKVVIYLCRNNTIQTMEELLFELQQTDPVNPVVLHCDNPPFYRFAASNKTSVVASGTTSSS--------------NTVVAGQENFQDTDEAKITRETEERLSSAARAHNRLESRYSNSSGGSYDEEKNDPLPPYAA---------WLISVLESNR-----------------PQSLPMPVNGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLHALFLGLDHYRPEVFEHSKRLLLHLLIALSCNNNFQVIASVLLLTREIGDNKTLTVKSSYQPEYVYTGGFDFLR-------EWQASPVADSGLSSS---------------STSSSVSLGGSIGNLPQITADLEELDESSTESEEK------------------------TNKLIEFLTTSAWSTVLSLLRAFGPLWCHEDITPKNLNSKSAEQLTNFLRHVVSVFKESKSDFHLEHQLSDVALQTALCSSSRHYAGRSFQIFRALRQPLSAHAVSDLLSRLVEVVGEHGDEVQGYVMEILLTLESVVDNLAECLNNSELMAALTRDSS--------PDFLVSGKLNLNRKSTGQINLLQEAG-------------TNERNRHQRSYSVPKKFGESGENSSSNPPRSATLDR-IQACTQQGLMRSARSTSSNSTRADTSVITDPSHSSHPVNLLATIFWVAVSLMESDFEFEYQMSLRLVHKLLARVPLDLQENRERLEKLQAQLRWSGFSGLQQLLLKGFTSPTTNDLTLQLFCQLTPVSRVPVVDTSQAIGFPLNVLCLLPHLVQHFGSPTQFCKESAERIAQVCLEEKDKNAKLSNLAHVMTLYKTRSYTRDPFSWVNVVCRYLHEAFSDITLSLVTYMAELLDKGLPSMQQPLLQIIYSLLSHMDLAGIQVKPFNVEVLKTIEKFVQTVHWKEALNILKLVVSRSASLSLPSYTHGDLAHLEVSRM-MWDGS----SKALPGKTMEFHFDISETPVIGRR------------YDDLQGSGGRDGKAR-AIAVTRS----------------------------------------TSSTSSGS-NSNT--------VLVPVS-WKRPQSSQKRTREKLVNVLSLCGQEVGLTKNPSVIFSSCGDLDLMEHQPSQVSSEDGTR-EDTLDDTTS-----EQQFRVFRDFDFLDVELEDGEGESMDNFNWGVRRRSLDSTDLT--ELLEE-SQHSDITPCIGIGIGIGLHDPQRDSDDSSEEESNSTSQSLSHSQLTMNLSPSEDTNHTDSLSTSYDTTSADPNSLNAATPCLGTSLPDDHIIPP-------VLPEDEESNIQEDDMPFGVNDLPMRFDCGSSTNLDLPAELN---------RAGINQNPNSLPSYHFGEDRDDLDELGFPPPPSPFFSAILAAFQPAVCDDSEEAWRSHVNQLMCDTDGSSAVYTFHIFSAMFQNMQNKFCSLTSDASTYLGEGLRGIGSKFVQSSDMLALCSDCPMLYVDAETIVSYGLLEKMKFSVLELQEYLDTYNTREEAVVSWLQNCKATFPR--------------FPDDGVITCQPGDSEEKQMETLAQLELCQRLYKLHFQLLLLFQSYCKLIG-QVNTISSVPELWNMSRELSDLKNCLRLAEASLAGD-LEDRHRHGSQSIFSSS-------ETAVQAILECLNNNDFSMAIRYTQECRRIWPN--------DIFGGGSED------EIQTLLNVYFRHQTIGQTGTFALVGSNKDMSEVCTKIMELNGEVRDMIRRAQGYQVISSSLVDSSVSGVSL-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9NYQ0-1", "uniprot_id": "A0A8M9NYQ0_DANRE", "id": "A0A8M9NYQ0-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------MEIQSYSERSYSELN----EENDGIEVVSMAS-----------------------------VPEDLMLSGDFRGKFKKIRYRKR----ASILSSSPGYTKPPVPP--------------------------------VCCSQGE-KGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEY-----CLPSILRTLFDWYKRQN-GVDDESHEYRPRSNTKSKNDEQQK-----------DYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHG-PNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLN-IFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFS-LNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTF--LSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDG--MSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTS--------------------------------------------KICSAELLQSSS-GSRLPAEW----------------------TSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLES-FAHVAVADSASLPAGQHADLQWLVEWN-GSLVG--SHYDVRSPSRVWILAQS----------------LKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPS-----------NPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSS--YDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVT-LLNLVLFKASDTNREIYEIAMQLMQILEAKLS---VYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSS--------------KTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAM---------WLMSVLETNQ-----------------PLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPD-FYTGGVDFLR-------NGQASPVPDSGLSSS---------------STSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEK------------------------SSKLIEFLTT----------RPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKSDIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVIL-RASS--------PDLPSSGKLTLNRKSTSQLELIPGSA------------TASERIRHQRSYSVPKRFG--EAERSSDVPRSATLDR-IHHHQSNISKLRSLSSSSSR---DNVVSTDPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEK--NSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSPSSPQSNSSSVDVRR--VWDTP----SKALPGKTLDFHFDISETPVIGRR------------YDELHGSPRQDGKNQGVVTVTRS----------------------------------------TSSTSSGSYQSNH--------VLVPVS-WKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSEDGTRDTENMDDTTS-----EQQFRVFRDFDFLDVELEDGEGETVDSFNWGARRRSIDSLDQTEAQPLEEDSQLSGSSPSLCP-------IIHDDSDESSEEESLTASQILSASQLNVSLSPTEDLNPMDSPPVSFDNTQADQIPLSTSTPSFEIPLPEGSNHRAEDS------AEEEEGIVNENDISLCICESPPAFSCSDILTLETPQREENFFTDEMSCVPSGFGEQFSSVAQAEEEKEELLLESRSSPPPSPFFSAILAAFQPTMCDDAEEAWRSHLNQLVADSDGSCAVYTFQVFSSLFQNIQSKFCTLTCDAAGYLGDGLRGIGAKFLRSSQMLTSCSECPTLFVDADTIVSYGLLEKMKFSVLELQEYLETYNNKKEAVISWLCNCKASFPK--------------CSEDGVITYQPAETEEKQMEYLAQLELCQRLYKLHFQLLLLFQSYCKLIG-QVHTINSVPELQNMSRELSDLRSNLRAAAASVAEENTGDRRDSSAESSFSSS-------EAAVQAILESLKNCDLSRAIRYIRECRKMWPS--------DIFGSSSEN------EIQTLLNIYFRHQTLGQTGTFALVGSKQDLSEICNRLTELNCEIRDMIRRAQGYRAITAFLPDSSVTGISL-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VT28-1", "uniprot_id": "FRY_DROME", "id": "Q9VT28-1", "name": "Protein furry", "aln": "-MDQLELQDDLFGLEAGVAGTNQNPNEQHLSDPAASPSTSSPANNNATAGAATTSTATVITAVGGAGGGVAAAGVGVVTPTKSPQRNAFQEDAYQANLAGGDSVDNIESAQLDGGNPSGGSPGQRHSINSAEYTSTPKTTRSGPNGSTTASGTTSPINYQLPGDDYPYGIEYESQQLLYQQQQQQQQQQSQQQQQQQQQQQQQLPVGDVEQSSAVTYQSLPVSRQSYASPPALIIPQRQSLLPWGAHSRSSIINVLPSYTQAEMHALAARVASVETSAPRPGEIVMRNLFSDFTAQAEKKIELVMLESADKNLSKLLQRGEDQQFDQLLSALGSVAEH-----CLPSLLHTLLAWHRRQLSDMEIKNDLKKPAPSGSSSQAATNKPT------VDLDFQLQRREAAVEFIFCLALIEILKQLPYHPGHEDLVRSIENLAFKHFKYKDGLQNNPNALNIHMIADLYAEVIGVLAQSRFASVRKRFMSELKELRGKEVSPTTTQSIISLLMGMKFFRVKMVPIEEFEASFQFMHECGQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCVKNFVELLYVQTLDASTKSKHRLALFPLVTCLLCVSQKTFFLTNWHYFLAMCLSNLKNRDAKMSRVALESLFRLLWVYMIRIKCESNSATHSRLQSIVNSLFPKGSKGVVPRDTPLN-IFVKIIQFIAQERLDFAMREIVYDLLCVGR-SIKLI-LNPERMSIGLRAFLVVADSLQQKAGEPPMPRTVPVLPSGNTLRVKKTFNKMYVLLTDDTARSIGMSTYFPHVRRVFVDILRALDVHYGRPLMMTNTQNQNKEPDEMLSGERKPRIDLFRTCVAAVPRLIPDT--MTPHELVDMLSRLSVHMDEELRILTHQSLTTLVIDFPDWRQDVVHGYTQFLVRDVTDTYPQLLENCTRILFTFLNIWRCATNVNGNNTTSAPSGATNVVNTSQAKMTTATTTTTVVQATVVQVTSAPAKDTASSQLSKQQHLNTASSAASSITTSSGMSSITQHTVLNMASDVGKKNEIPLATTLHFVEGFALVLLCNYRTYLRKLAALILKEVKNLMRALGIPETEP-PLIDVMDRCVPGIIEKCLPQLPQTEKTAILNANCIDLQWIAERSSGVWLAGLTDDNSKSSTSTLNLSQSSSTPNASATAASSPQLPFDPWATCLFGLLERQNVLQQCPSAVAQAWPICFTRLNALYSVIDPTPVSDNRASLLRSSAPTKKVPTESQKDSYLRLWRN-QVACAMRLVPQIPSVAVRCASPDLSLSSSPDSLNADRSDKSAMGSASPQALYKLVVPLLRCEVVDVRDAAVNALGLINHDALKDLMEELVVYIREAVDCKQENMRRRRRRDALRLQVVRVLEKIAENGTFGVST-CVLERDTMSLHPTFVLYISGAMGYLTSETDKDNLSIREVKAHFCNFIRKMIKNFPLEACATLLSR-VLKRNLFNLFAAWCGSFSKPLG-YTMQSDHTLEEEKLQFSALQAMSALLCCGQIFNPSYLQDDSIIYKWLDMLLTSKNEKIYQLARDTVVLLLESNPDIGQLLEWVIDRCYTSTPREADACFLALASIFSAKEYPCDHYTSVITVTLLMTGCPRVEVHATALQLLQILDKRFFGSVVGTLHSDSDKEDDKVGTLDVLLSSAYCRSQRFLSKQLAQLRPELTMSIFSEITHRFQSAREDVRALLLQCLLPWLQNMELVAT-----SVPPATPLSYIMYFPD---SGTRGRREGTGSTEATEMILNNLFYITAKFSDAHPR-DIEELWGTLC--QFWPNNLKVILRYLVIMSGMAP-TELLPYAKRVALYLVRSCPDRLLDELMAELQTVETLNCLIERTETPPFYRLTSMRKASSHSADGQAAGGINDSRIQDLAVEKGTIHTKRHSGEDPMKIGTCKSDSGIRAYTQAAAAAAAAAVTPGSSGNRPPRGADKIRAASGPSILPRPEDILINDPELRQEENVELRGTSDAAPNGHPHPLPMPEYGGYFAPLTEFLPDVSLPISGFHRCNVAVMLLTDIVVDGIPGIDWTLHLPLMLHILFLGLDHTRIIVREHCKQLCVNLLIVLAEHNDHLTVARILLNSETSKLDLGLTVPALPVIDNNFTELHQQFDSYLLHVSPQAAAYALQHNLSSSTIIAAHHQNLSQTPQSQQQTGSQNGQTTTPPGLTATPAALQINPNNSENSEVPLIHPDEHAPPQPGPSMPIAHVIKSLLKFLAQ----------DTCQPLWNYEDITAKVWAVKSAEQLSCFLKHMVKVFADSYPQARIAERWAQTALQLGLSCSSRHYAGRCLQIFRALNVPINSRMLSDILSRLVETVAEQGEDMQGYVTELLLTLEAAVDSLDSDFRPLDVMKDIFKSTPNLNNKDGGPNSILPGKKSPSGMTPQSSNYSIPSHG------RSTSYSVSYCGRKANNSPCDKQVELRNRSSGIDLERSVVCKFGVGGGGAGSALSRSRSAQS------LKMLGDTATQDDKMTILAQLFWLSVSLLESDYEHEFMLALRLLTRVLHRLPLDRPDARDKVEKLQQQLKWTAYPGVHALLLKGCTHSATYEPTITLLSQFAPLLTLPVCDPTQSCAFPMNVIALLPYMLLHYEDANEICIRSAENIAQVSTELG---AKLENLGTVMTLYSRKTFCKESFQWTKCVVKYLHDTYAHMGLHMVAFLIEVLEKGPQQVQVPVLNVIHCMLHYVDLSAPQAQSINADLLRAIGKYLDTAYWKDSLKILKLIVTRSSSLQVVPPSDGSSAGLSFSFYGAYPDSDMFCKKELAGRTMEFTFDVSQTPLIGRRILLKTEEPVAGGAVSTTGSSSLNSTLTNATTVTVAPSAAQQQTNVQMQQQRANTNVAALAAAAAAQHQQQQHAIGAGSSVVGTPNSPRRSASLSPADTVPLSGWKRPWMSQCRVRECLVNLLTTCGQRVGLPKSPSVIFSQS--SDLMERQSSAASSTEETSGPQGDLSSGSRRDDGQPDFTVFKDFDFLEYEDS-IAGESTDNFNWGVRRH----------QLFEGDEDRLNCGSGIGG-------SIKGGHSSAFEDSFSDKTPILSKRKRQIADDSSDEEAESES-PLDEDHRQSFLKSGYSAVPPTSLSLRE---------------RRRRNSVSRSDTSGSSAGDLGDLTPCNASPHLPG-----------------------------------------------------IIRFSAAIHDEAEENWRRQVQALLVNQPSAHTSELLQQLYRLIKELTFKTVNISKEAKKFFTGIGSQLGNRISLFTDLLSSRADPPQVWCSELQATSPKLFETLRFNVLEVQEHLETFFDRKDQVLECLDAVKTSCKLSLFNEADVAASGLELPSTSSIVYMPFDPAST----EVVLDLGRSLYKLMFQLLLLIESNHKISSNVVNHFRMNEDMHDISDLYALVRDALVRYISEAELDCLESSTSTEGEHTPTPSPGLPMTPEEFEAVLTEHIDLQRWPSAIAHVRQYRRISTLNASGYQNVTIFSYNSADNRQKWDEISVILNAYAHGIMKDRTEAFIVSKSDSEVFEIYAILSENLYQVSSALTNMEISMKSYSAGSASGNSHRSEQDIVTNL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40468-1", "uniprot_id": "TAO3_YEAST", "id": "P40468-1", "name": "Cell morphogenesis protein PAG1", "aln": "MASRFTFPPQRDQGIGFTFPPTNKAEGSSNNNQISIDIDPSGQDVLEEINEAPLNTFPLHQSVTDAPIIDIPSPTDMSEGTSLNNQLLLRQQQQQGTGEGQALPPTFVEEQSDQNKISMLLPEQKQQRMQESAPPDITAKSVAEDYVTTLR---------------------------QQMATDWKSPSEYALHILFTKFIRYAENKLNMCLQQLDMAEPPIVEILGEG--------------------------VDPSFDEIIKSLGHIAKKKPKPVIDAMMFWRKTKSEAANSASEEMEKLLKEYEFEKAHPSQAHFLMNRRLSRSSSNTTSKYKHNNNTNNLPGMKRHVSSSFNNKVPLIKASSSNNSATSSPSIANSQLKSLENTIEVAKEEAFLADRKSLISIYILCRVLNEIVKQASSN-EEEDLSDKLEEIVFTQLKTTD-PLSISTSLIKSSNWNSFAELLGSMSEKKFLSVSDRFIADLEKIP-AYIPPELEPSTHLLILGMRYLKLRNYPLEKFEESADFMKSLSKFFAKTENFPVCLAYAEVTNQLLLPLAGSLTAEVNHPTWVEAMSTLLNTAKRLQADSKYWVSGFKLTVSILCASPPDLFSKQWLSLLEANASKVKSKSLNERIIFAVGLSRLVWVYLYRCPETLNNTTRTLTKLLQLYLNTRKKENWITGDFGLLNPLTDALISIGFLHPNFLMEQALIPLIRQSFNGSNLENINYEKLILTINTYKGLLVTKER----PRFPEDDNRLYELNLNNITVNQVQEASSINHTEISDYFYKLFLLLDSSIGSEVWSPENQHQKQSSNAFSPFGFSFSNDNDSSKNKSLYVILFGTIIEAIPCCLSISRTIPYKSTIEILSRNAVHSEVIISSSSQNALRALASKKNPYTLITWFAKYSFDFDEKTQSSYNMSYLSSKEYNRLLILYVELLECWLEEFQSSN------------------------------------------KEENKKETGLDGIRLLPIDAEQ-----------EESNETEKLEWKNTVTVIEEVEGNGLFFLCSHDAKIRRLGIQILRIIFKFDEAMMEKTEKLSNGHSRSSSHFAADRGTRLIDLLNECNTTTLINPHKATLSAVEKTRFSRLN--SKYKRGLLIKLAESEYG---------------VDAALWQRAFPKLLA--LVFKTCPMAMALCRSIVCIRLVQVHEIILRVAN------------DVDFKLKNVLPETIVNQWKLYLIAACTSLTSTFDQKLHIPSNIPQHGRKKSQQIFT----VQHQKIKSAKSIFKMVLPLLNAKYIMIRDAIITGLSSMNINIFKAYVEAIDVFLVAWKEGSSNNQIR--------------VEMFHILTILSPYLKSDMIFNDEWILRKLSEFLQKTKQFLEKDSVQISYEYQSLRSYFAGLILSYYMAVREHPLIDELFPFQARASCFNFLKEWCG-----------YGEYEPISEERYAIMIKNTESGRDRTAITTGIEFQKNRLQMIVLETMVVLCSDPITQTLDDDLELPIVISFDTEDLLAWIEALFDSDNTTVKNLGVRALENLLDKNRENFKLFRDVAFQCVSHHSHPSVAVLYYTTLCKSVLKLDNL--VLDEDELVSLGLYGLVADKEDTRTFAVDLLSAVETKLHNSSYTKVFKERLANSSKTVYKSTAKEISSIFAELLSQDLCLRIFSSLVRILDLFPFEIKRDLLVLMVPWVNKFTLKS---LEELDTFMVLNNLFYITIDLNDSLPN-EVEQLWISLGKGNSFQN-IHVSLEYIINSSMNHCNPLFVQYARDIVLYLANIPGGIGLLDTLLNNLEPKYMVPLAKHTFNEPMNNNKYSFLGNIWERLN----------------------------------------------------------------------------YNG-------------------------------------------------------------KRIIFSKAQLSIIFLVNLLTN--LSESVKAKIPLLLHMSICLLDHYVPLIHESACKIASTLIFGLAPSHEKSEETVKLLRNKHA---------------------------------------------------------------------------------------------------------------------------------------------------LWSYDNLMKKG--ARSPKTMDLLIRNIISIFSDLD---EFQVTWQRIALKWATTCSVRHIACRSFQIFRSLLTFLDQEMLRDMLHRLSNTISDGNVDIQGFAMQILMTLNAIMAELDPTN---------------------------------------------------------------------------------------------------------------------------------------LISFPQLFWSITACLSSIHEQEFIEVLSCLSKFISKIDLDSPDTVQCLVAIFPSNWEGRFDGLQQIVMTGLRSANSLEITWKFLDKLNLLKDSRIIANTESR-LLFALIANLPRFLNAMDRKDFTGIQVAADSLIELANAY----KQPSLSRLIDSLAKNKFRSKKDFMSQVVSFISRNYFPSYSAQTLVFLLGLLFNKIGWIRVQTLEILKYVFPLIDLRRPEFIGVGADLISPLLRLLFTEYEAKALEVLDCVPNVSGSKMDKDVLRITMGNKDVKD---------------GDNATTTLFGLPEDSGWSVP---------------------------------------------------------------------------------------------------------MPTMTAATTRHNVHAVFMTCGTGK-----------------------SDEVSAHGSDDMDAVIEFHA-----DGDYELGRMDTIVEFHAD------------G----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DYDLGRMDTNDSISVAEEKDASLSHMWAELDNLDSFFTKDTNVPNISSKMGMGIPHGRSDSIETTRTDQTFSFESAPQLYDKKVSVILNRSLSRTPSNVSFKTHLADSFAVKINRNGKPRI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *: :. . . :. .: :*. .:: :* . : : ::.: * * :: **.: : : ...: :. .. . .. . . : : :*:. :*:. .* *::** . : :.* .: .:.*.::* .: . ..: : :**::* ::: :* :* .:* ::*::: * * *::*::::::: *:*.** * :**:. .::* :.:: : : * : ::*:*:*.::. *** * : :. * : .: .*: : : :...:**.* :* ..* :* *::*.:. : : .* **:***: * *.:*: : * .: ... :. * * :.. : *. : :* *.: : :: . . : :* *:: : :.:: : . :: * :* * . * . . . :.. : :: : . : . . . :: : ::. : ** * : *:* :. :. . :::*:* ::* : : ::::* * . : . . .* . : : : . : :* : . . . . : .. :.:. *** .*.:**. *:*. :*: : : : . . . . . : .: .:: .* . : :. . . * .: :* : : ** *:: . . ** : :: .. . : : *: : . . : . :. ..: : . * : * ::**:. : : : :: : .:. * :: :* : : : :* * .* : :. : : : : ::. : * :. : :.::::*. :: . . . : : * :: *.* .: . :: .: : :. : *: ::. . : : : : * : . * :*: * :.. . . *: .: . .. . : : . . : : .:*. : . : . . : .:: ::: :: . .: . :: **. :.:. * : . : ::****:::* . .* * ::*: * :* : : * :: *.::: . . :: : : :. ** . : : : : . : : : . *: . : :.:::::::.:::.: . ::**:** : :** : * . :: *:: *: : : ** .. ** :::: * :*.: : ::::::.:* : .: **: . .* ** * *.:*:**:* :. : *:* ** :.:.: . ::**:. : *:**:: : .* :. :** .: :.* .* *: * : :.: :: *: : : : : . : *:: :::.* : : * :: : : : :.: : : ::. :* :: * : * .*. :: ..: . : * :: :. :.:: :* : :: *::: :: :** .. ::: .: : : : : .:*::*. : . *.* . .. ..: *.:.: . . * : .:. : :: ** * * . . : . : : :: : : ::: . . * .: : : : : : : :: :: :: :* .: : :: . : . . : :. .: . . :. : : . ", "identical_positions": 211, "similar_positions": 721, "identity": "5.81%" }, { "cls_id": "homologset.agr.MGI:2443902", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2VWQ2-1", "uniprot_id": "NELL1_MOUSE", "id": "Q2VWQ2-1", "name": "Protein kinase C-binding protein NELL1", "aln": "MPMDVILVLWFCVCTARTVLGFGMDPDLQMDIITELDLVNTTLGVTQVAGLHNASKAFLFQDVQREIHSAPHVSEKLIQLFRNKSEFTFLATVQQKPSTSGVILSIRELEHSYFELESSGPREEIRYHYIHGGKPRTEALPYRMADGQWHKVALSVSASHLLLHVDCNRIYERVIDPPETNLPPGSNLWLGQRNQKHGFFKGIIQDGKIIFMPNGFITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAETRLGQLENCHCEKTCQVSGLLYRDQDSWVDGDNCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHISGQCCKVCRPKCIYGGKVLAEGQRILTKTCRECRGGVLVKITEACPPLNCSEKDHILPENQCCRVCRGHNFCAEAPKCGENSECKNWNTKATCECKNGYISVQGNSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCIPGYIRVDDFSCTEHDDCGSGQHNCDKNAICTNTVQGHSCTCQPGYVGNGTVCKAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECAEGFVECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWILREDRCSVCSCKDGKIFCRRTACDCQNPNVDLFCCPECDTRVTSQCLDQSGQKLYRSGDNWTHSCQQCRCLEGEADCWPLACPSLSCEYTAIFEGECCPRCVSDPCLADNIAYDIRKTCLDSSGISRLSGAVWTMAGSPCTTCQCKNGRVCCSVDLVCLENN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62919-1", "uniprot_id": "NELL1_RAT", "id": "Q62919-1", "name": "Protein kinase C-binding protein NELL1", "aln": "MPMDVILVLWFCVCTARTVLGFGMDPDLQLDIISELDLVNTTLGVTQVAGLHNASKAFLFQDVQREIHSAPHVSEKLIQLFRNKSEFTFLATVQQKPSTSGVILSIRELEHSYFELESSGPREEIRYHYIHGGKPRTEALPYRMADGQWHKVALSVSASHLLLHIDCNRIYERVIDPPETNLPPGSNLWLGQRNQKHGFFKGIIQDGKIIFMPNGFITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAETRLGQLENCHCEKTCQVSGLLYRDQDSWVDGDNCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHISGQCCKVCRPKCIYGGKVLAEGQRILTKTCRECRGGVLVKITEACPPLNCSAKDHILPENQCCRVCPGHNFCAEAPKCGENSECKNWNTKATCECKNGYISVQGNSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDDCGSGQHNCDKNAICTNTVQGHSCTCQPGYVGNGTICKAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECAEGFVECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWILREDRCSVCSCKDGKIFCRRTACDCQNPNVDLFCCPECDTRVTSQCLDQSGQKLYRSGDNWTHSCQQCRCLEGEADCWPLACPSLGCEYTAMFEGECCPRCVSDPCLADNIAYDIRKTCLDSFGVSRLSGAVWTMAGSPCTTCKCKNGRVCCSVDLECIENN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92832-1", "uniprot_id": "NELL1_HUMAN", "id": "Q92832-1", "name": "Protein kinase C-binding protein NELL1", "aln": "MPMDLILVVWFCVCTARTVVGFGMDPDLQMDIVTELDLVNTTLGVAQVSGMHNASKAFLFQDIEREIHAAPHVSEKLIQLFRNKSEFTILATVQQKPSTSGVILSIRELEHSYFELESSGLRDEIRYHYIHNGKPRTEALPYRMADGQWHKVALSVSASHLLLHVDCNRIYERVIDPPDTNLPPGINLWLGQRNQKHGLFKGIIQDGKIIFMPNGYITQCPNLNHTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAETRLSQLENCHCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAGSPCTTCKCKNGRVCCSVDFECLQNN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:***:**********:*********:**::***********:**:*:***********::****:*******************:******************************* *:********.********************************:*************:****** ************:****************:********:************************************.****************************:********************************:***************************:************** ******* ************** *******.*********************.*******:**********************************:***************:*********:***************:********:*:*************************************:**::***************************************************************************************** *:**************************..*******************.*:**********************.*****:**.*.*****::******************:********** *:*****:************:***********: *::**", "identical_positions": 748, "similar_positions": 54, "identity": "92.35%" }, { "cls_id": "homologset.agr.MGI:2443910", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LYC7-1", "uniprot_id": "F1LYC7_RAT", "id": "F1LYC7-1", "name": "", "aln": "-----------------MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKVELTAVGSGSNARGTNPDGSTTEKLGHRSEDQPDDPQAKMDYVGNTAEAEGLLVPLSSPGDSLKLPTPDGTEASHSRANCSWTPLSTQMSKQVDCSPAGVKALDSRHSVGEKNTFILATLGTGVPVEGTLPLVTTNFSQLPAPICPPAPGSASGTPSVPDPFQVPLS--------------VPAPVPHSGLVPVQVATSASAPSPPLAPVPALAPAAPSVPTLISDSNPLSVSASVLVPVPVSAPHSVPVPLSAPAPTPLTVSVSAPPLALIQAPVPPSAPTLVLASVPTPVLAPMPASTPPAAPAPPSVP--MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGT----------------------------VLTPNQPLVYIPPPSCGQPLSVAT---------LPTTLGVSSTLTLPVLPSYLQDRCLPG--VLASPELRSYPYAFSVARPLASDSKLVSLEVNRLSCTSPSSSTNSQ---------------PAPEG----VPGPLADTSLTTASAKVLPTSQPLLPAPSGSSVPLHPSKMP-----------GGTDQQTEGTSVTFSPLKSPPQ-LEREMASPPECS--EMPLDLSSKSN-------------RQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGSNVTSCLGSTSSPFVIFPEMVRNGDPSTWVKN-STALISTIPGTYVGVANPVPASLLLNKD-PNLGLNRDPRHLPKQEPISIID--QGEPKSTGVTCGKKGSQVAAEGQPSTVKSRYTPARIAPGLPGCQTKELSLWKPTGLTNMYPRCSINGKPTSTQ------------------QVLPVGWSPYHQASLLSIGISSAGQLTPSQGVPLRPTSIVSEFSGVSSLGSSE---------AVHGLPEGQPRPGGPFAPEQDAVTKNKT-CRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPNSGDIGVNQGSEESESHLCSDSTPKVEGPQAACGLKLAGDTKPKSQVLATYMSHELVLANPQNLCKMPELPLLPHDSHSKELILDVVPSSERGPSTDLSQLGSQVDLGRVKMEKADGDVVFNLANCFRADGLPAVPQRGQAEARAKAGQARVKREGVGVFTCKNSWQPDEETESLPPKKVKCNKEKEIEEEPQQQLPPQPHDKPMVRSSVGSKCRKLPGDPQEPTKKSPRGALDSGKEHNGVRGKHKH-RKPTKPESLPAGKRADGHEEGSLEKKAKS-----------SFRDFIPVVLSTRTRSQSGSICSSFTGLADSDMGSQEVFPTEEEEEVAPTPAKRRKVRKTQRDTQYRSHHAQDKT-----LLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEDEEEEG--LVKRKKRRRQKSRKYQTGEYLTEQE-----EQRRKGRADSKARKQKTSS-QSSEHCLRNRDLLLSSKAQGISDSPNGFLPNNLEEPACLENSEKP-------SGKRKCKTKHMANVSEEARSKGRWSQQKTRS--------------SKSPTPVKPTEPCTPS--KYRSAG--SEETSESPTARQIPPEARRLIVNKNAGETLLQRAARLGYKDVVLYCLQKHSEDVNHRDNAGYTALHEACSRGWTDILNILLQHGANVNCSSQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDNMKRFLSDHLSDLQGRAEGDPRASWD---------FYSSSVLEKKDGFACDLLHNPPGS--------AEQ-GDD-SEQDDFMFELSDK-----------PLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSS----------------------------RIFQARFPHLEITTLPKAEFYRQVASSQLLTPAERPGSLEDRSPPGSSETVELVQYEP----------------ELLRLLGSEVEYQSWSS---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AQH4-1", "uniprot_id": "BCORL_MOUSE", "id": "A2AQH4-1", "name": "BCL-6 corepressor-like protein 1", "aln": "-----------------MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGGCQHFGSQEFCVSSSFSKVELTAVGSGSNARGTNPDGNTTEKLGHRSEDQSDDPQPKMDYVGNPAEAEGLLVPLSSPGDGLKLPTPDSTEASHSRANCSWTPLSTQMSKQVDCSPAGVKALDSRHGVGEKNTFILATLGTGVPVEGTLPLVTTNFSQLPAPICPPAPGSASGTPSVPDPFQVPLS--------------VPAPVPHSGLVPVQVATSASAPSPPLA------PAAPSVPTLISDSNPLSVSASVLVPVPVSAPHSVPVPLSAPAPTPLTVSVSAPPLALIQAPVPPSAPTLVLASVPTPVLAPMPASTPPAAPAPPSVP--MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGT----------------------------VLTPNQPLVYIPPPSCGQPLSVAT---------LPTTLGVSSTLTLPVLPSYLQDRCLPG--VLASPDLRSYPCAFSVARPLASDSKLVSLEVNRLSCTSPSSSTNSQ---------------PAPDG----VPGPLADTSLTTASAKVLPTSQLLLPAPSGSSVPPHPSKMP-----------GGTDQQTEGTSVTFSPLKSPPQ-LEREMASPPECS--EMPLDLSAKSN-------------RQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGSNVTSCLGSTSSPFVIFPEMVRNGDPSTWVKN-STALISTIPGTYVGVANPVPASLLLNKD-PNLGLNRDPRHLPKQEPISIID--QGEPKSTSATCGKKGSQAGAEGQPSTVKSRYTPARIAPGLPGCQTKELSLWKPTGLTNMYPRCSINGKPTST-------------------QVLPVGWSPYHQASLLSIGISSAGQLTPSQGVPIRPTSIVSEFSGVSPLGSSE---------TVHGLPEGQPRPGGPFAPEQDAVTKNKN-CRIAAKPYEEQVNPVLLTLSPQSGTLALSVQPSSGDMGVNQGSEESESHLCSDSTPKMEGPQAACGLKLAGDTKPKNQVLATYMSHELVLANPQNLCKMPELPLLPHDSHSKELILDVVPSSERGPSTDLSQLGSQVDLGRVKMEKADGDVVFNLANCFRADGLPAVPQRGQAEARANAGQARVKRESIGVFTCKNSWQPDEETESLPPKKVKCNKEKEIEEEPRQQPPPQPHDKPMVRSSLGSKCRKLPGDPQEPTKKSPRGALDSGKEHNGVRGKHKH-RKPTKPESQPPGKRTDGHEEGSLEKKAKN-----------SFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVAPTPAKRRKVRKTQRDTQYRSHHAQDKT-----LLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEDDEEEG--LVKRKKRRRQKSRKYQTGEYLIEQE-----EQRRKGRADSKARKQKTSS-QSSEHCLRNRNLLLSSKAQGISDSPNGFLPDNLEEPACLENPEKP-------SGKRKCKTKHMANASEEARSKGRWSQQKTRS--------------SKSPTPVKPTEPCTPS--KYRSAG--PEEASESPTARQIPPEARRLIVNKNAGETLLQRAARLGYKDVVLYCLQKHSEDVNHRDNAGYTALHEACSRGWTDILNILLQHGANVNCSSQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDNMKRFLSDHLSDLQGRAEGDPRASWD---------FYSSSVLEKKDGFACDLLHNPPGS--------AEQ-GDD-SEQDDFMFELSDK-----------PLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSS----------------------------RIFQARFPHLEITTLPKAEFYRQVASSQLLSPAERPGSLEDRSPPGSSETVELVQYEP----------------ELLRLLGSEVEYQSWSS---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5H9F3-3", "uniprot_id": "BCORL_HUMAN", "id": "Q5H9F3-3", "name": "BCL-6 corepressor-like protein 1", "aln": "-----------------MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKVELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGDGLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLS--------------VPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVP--MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGT----------------------------VLTPSQPLVYIPPPSCGQPLSVAT---------LPTTLGVSSTLTLPVLPSYLQDRCLPG--VLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQ---------------PAPDG----VPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMP-----------SGTEQQTEGTSVTFSPLKSPPQ-LEREMASPPECS--EMPLDLSSKSN-------------RQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKN-STALISTIPGTYVGVANPVPASLLLNKD-PNLGLNRDPRHLPKQEPISIID--QGEPKGTGATCGKKGSQAGAEGQPSTVK-RYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTST-------------------QVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSE---------AVHGLPEGQPRPGGSFVPEQDPVTKNKT-CRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSDSTPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKELILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQAEVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQ-----LQPQAKAVVRSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKH-RKPTKPESQSPGKRADSHEEGSLEKKAKS-----------SFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKS-----LLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEG--LLKRKKRRRQKSRKYQTGEYLTEQED----EQRRKGRADLKARKQKTSSSQSLEHRLRNRNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKP-------SGKRKCKTKHMATVSEEAKGKGRWSQQKTRS--------------PKSPTPVKPTEPCTPS--KSRSAS--SEEASESPTARQIPPEARRLIVNKNAGETLLQRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWD---------FYSSSVLEEKDGFACDLLHNPPGS--------SDQEGDDPMEEDDFMFELSDK-----------PLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSS----------------------------RIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSPPGSSETVELVRYEP----------------DLLRLLGSEVEFQSCNS---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKM1-1", "uniprot_id": "A0A8M2BKM1_DANRE", "id": "A0A8M2BKM1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQVDPSPMNVGDGGTVSRESSAPTQVSESMVGNPQQTLPLELRG------DVPQSQQNKLRVTTDCKTPDVCSEASNSNHCPQVPSSQP--HSN-VFSTDPVNTP--LPDRIEVSKGKIDGAGIFSTHQWPCGKKVTTEDPVNS-VHSNINLNKKTNAPAPTQPVISVPLGFQCST----------------------------LFKPGQPVAFLPTSNFSSPLCKIT---------LPPGLGQIAALREATASQFQKDCPAQSSCSSTTPMLKTYPYHFSVGRGPGAEKKHPSSGS-KVRCDSLSKGFQAR---------------VEHKGPMSSVAAPALALPVQQATQGSAPPTRYTISPTAAICCSPALANITTQSRLLSLVEKGSTFRGAEKTSLAYLKPKTLSTPEELNVSCPVEPR--DVPLDLSAKSK-------------RQKSIKDTQNNPSVATEHHSVEAHQKNITGSKKIHSASFHGSSSTFDTQRNGATQKSSSKLTNHHALEPNTSWVKSSSSGSLNNLPGTYVGVASPILASTLRSKDGKGAAFVEDLQTFAKQETISIID--QGEQ----PVCRERKAQFAVKGSQ-----------------HNKSGKLSTGTQQGFLSTQLCATVNSQPHRK-----------------------------------SVGGKGGTLFTPPVKSLWQPPCVHSQGASLQKKPSQT---------QAPKTKSTLSCERALFHNSHLSPTKVEDEKWEKAKSPLSNLESIVKQKTLETTALTGENYCNLSSVGSKRPEVVSIQNRCQDSTLQQTLTAGSPPFRTIEGQVIKTDRTSPQTDSTAALNRPE----ITTVPVPKDKGREKQTKQTENQSSDSRQKIKSSTP-SKRSSPSIKVEWKERKLVQHLEDET---------AKEKASERKISSHVKVEGIALSLLQSNTVEVEGEAKINGAKEEIPSKGKVSIIKQK--------NLKKHAKEKTPSEVQKKTAPRKQKDKDSP-----SVKQGLSHKKQKKD-VLPGVGKSVLKDGTGPGPKAGGKTRKGK------------SCPANVEHTDSNKIDSESSPCRSPQVDRDSGSLSSPGWPSKESDSQEEASPRLRRGRRRTDEALLRDWSFATPPTPP---PLDPPSTPPPVPVRRPRGRPRINPLPEEVDADKDRPTEGGDTSSIKKRKRCKNRKYQNGEYITEKDKVADGEEEKLGVEDGEATNEKTGVYPCLSATLTGEVPSPDVSPRRTLFTRSGLTRPQDSPPATHPNTDKP-------AGKRKFKSKHLCDTDEQKKLKTKKGSLGKRTGPLVLDEDGPPAKKTPTPLCASPKPPHSPLSGKKGTAG--KSGIPESTPSRPVPPEVRRLIVNKNAGETLLQRAARLGYQDVVLYCLEKDVREVNRRDNAGYTALHEACARGWTHIVQVLLKHGADVNCSAQDGTRPIHDAVAADNLPAVWMLLNHGADPTLATYSGQTAVKLAQSPSMKTFLKEYFTDLEGRTDQDPSLQWD---------FYSSSVFEKDQEPCWDFLLSQPEDE--GEEMFSEQVKERDADADCLLFEFSSE-----------PLLSCYHVQVSLTQGFCNWFLLADVLKRLKMSA----------------------------RIFRARYPQFEVVNIAQAELWKQVSVSQTCSPPDE---LQPEDDEDGEETVELVRCVP----------------ELQGLLGSSIQILRDDDNDNDEDDDDKSALRPCSR---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQT4-1", "uniprot_id": "Q8IQT4_DROME", "id": "Q8IQT4-1", "name": "Protein piccolo", "aln": "MEPNRHHEYQTHHQPHPSMQHHPTHPHHQQPHHQQPHHPQQPIHQHHPPPPPPQPQQQHQPPQQIHQQQQQHPHHYQQLHHHPTSSTSVGSSSSASYVNHHPQHHPTSLAEDQRGSRSAIYMSRSTQPGLPPPHPHSSAQGSGAAGTSGSDPHMQYYTSNQNLAIKKMSDPHPMWSYKSQAVTTPAPAPGLRQHGNPALYPTGSTAYWPPPDEQLHHQQPSRYSYAKPGGPVTGSRPIQGPLPNSQRYYSEDIKYSTVPAASKVLTYAPPASSSQPQPPPPTSSSSANSSSVRHYELDVVNPSNPSNEHQQPSPNYGRKCPPHYETPPEQRSAGATPNSTGTPTSTSHHQSLYIPMPTFSTEKFQTTVHNAIEKYIRETPGPSLEYPRGGVAPVGRTGYYNQQPMKSSKAPPSVPQTATSSYVKMEPEHALAGGLPQPTRSSLYHNPYNVESRERDSSPAMATVPAPHGYPTKYGKLIQQQHAASGVGTGSSAPYQSYYHQGTPSPAAGAVASPTPAPLPPLAEAPGTIFGPGTGLNPGIPPHSSQPVPPPANSQQPASSSSSSNANFSTLQVYPHGPDICYQPGSQTQAQNQTQNHPNPAKKSPAVTKPNYRALINDMLKRNTASEQELNLQIIKKTLNMEPASSRNHSAPSRVIQQSAAPAAISIPSAPPPPPPAIHSPLDLSMRTVKQTADSTEYKYQRPSTDYKLPQGGLGGGLGLPRFDITPNFSAATRGGAPTSPAPTPVIRQAVAIQPAPVPPTVPVPPAVAAPALVIKTVQQMRPSVVETNPFAKRQQQLPPETSIVQVTKPTVELMPTPSPSPHNSSNPNYLGKKRHLQEYNQAAAKQARLDAESSGSLVSGAPVIAAPTSVVVVAPVPVIAVNEQALAAKREREMQSMSAESSTSAHLVPKMEPRIRTKAELKGFTFTPPVLVTSTTNASSTISPPRTPPNQITNHIQIKLEPAPPKATDLGLDDEQHSLGNLMDWGSTCNNLVEQLMSKVVVPPTLPANNPGIKLELSEDDLPVARILKRQPLAAPSLAGGDAESATTQLTTTTNGISSSLGNGSGQKKLSKVEREKKRQQQEQRIAARLAPKQGQSSSSESDTTELHKRNTARQKKPLLRKGRTRQRSPEAASIQQSSDEEQEKVSQRLSRKPRTSSEESKTKATSAKKDVKKEAKTPSNKTNNSASLTKIKKKTTDSSSLNKAKGDENPKQESQESTSSESDQDDNDNDNDEEEEDQEEDEEEPEEEDDDEEQDKKKEKRVGRRPGNTLKKRIAHKLNTMTRSKHRKELELQLANSKVLRNDKIIRNSTTKIKRKYVRKVVDSKKEMMVTRLRNKRGMNSDLGALNGRNSKLKGSKVGNSPGKPKTSPQQQLYLEEYRYKLALKIPHSLISINKLNKVASSLPDLERRDLSQELACFKRNRPKTKAASKQDFTPKSIIDVLHLRVTNGSTAGTQRKISVSAPASTNLQIHSETSQTSASTSLYEQSQQDNPTENQSLDDMSKRHFSIFDTKVLQSKTRTETKLQ----KHREIIREIFVGPERPASAPPECVQEADGGDAISYQKYEEFLQQMNSIASANDSKLARRSLMEDKSVTAPQCPHKRKYRCRKGSSGFDYIRKKKRPAPTQTQNHTQNQSQSQVSSQITQHILEHNQSAADERLEDTDSTIAGSSHLPPKVKTEMDVCREIQKWVLNKGVGQSTMHKAARQGLIDVVVYCLDRMNMNPDQKDNAGYTPLHEACTQGWLEIARILLQYGANHSEAAQSGIRPLHGAIENDHEEVVRLLLSYGADPLLATYSGQTPLMLASSKLMRGILRAHLSDAQSAAADIKPMRFNGPWEIFDAKEYGYDIFSNVPNTACDMSRALRKERKEAKQQRMSSNSDRTSNLNGLLAEKKEEQKPEDLDQDRVTTTIKQNGETSATKTGSATTTTATTMVKLELGTDEDSNNNKNNEELNANVENNLVTSVVNVKNEVKKEVEAEAETEAETETNAKANTNSSTRLDEDQTDIETMDSELNGDIFEFEEADVPLPPLYLLKDEGSDKWVLLNDLCNLLKVKSKDTLLNKLCPNNSNALASSQKHLLREFKIDDFLEKATCLQLLCAGEKLNMFSSSKVVLIKYNDSVRNLLGVKTILMKF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..* . ..* . . . . . . *. . . . . * . :. . . . : .. . . .: .:. .: : . .* .: .* . *.. **. . * . : :: . .. : . . *: ** .: ::.: . : . * . . : . . . . ...:. . . . . . : :: *. : .: : :. ::. ::*: :. ** .. . .* : : :. . . . . .: *: :: . *. . . .: . :. .: :: . :: : . : :: . .: . * . * . . *. : :: ..: *. . . : . *. . .::. : . : . . : . ::: : : . : : . .. . . . *: .* . .: .:: . . : . : . . .: . : : : . : : .... : : : :. * *: : ::* . . . : *. * * : * .: . *. . .:.. ... : .:. : . :. . : : : :: :. . :: ..: *. : :... . :. :. . . . ..: : . * :. . *** : :: . : : * : . .:. . . . . . : . .: . : * :: ::**..*:: :::*** * ***:***:: : :::******.*****::** .* .:**::**: . ::*.* **:*.*: *: .: :**.:**** ********.: **.* *: :* :::* :. : :: *. .::.: . *: . .. : : : :: * ..: . : :.* :: . : .: :*::.: : : . * . .::* :. .. : :: . . : .*: . * * . :: . ", "identical_positions": 111, "similar_positions": 417, "identity": "5.19%" }, { "cls_id": "homologset.agr.MGI:2443921", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZR43-1", "uniprot_id": "A0A8I5ZR43_RAT", "id": "A0A8I5ZR43-1", "name": "", "aln": "MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHGCFQEGRSPTGAQP-ASAKPPPLSAKDLLLQPPPQLGHAGAEAAR--AQAMERYPLAP--DRAPRLASEF-STRAGAGLPQSAASQPSPANGILVPNGFSKLEEPPELNRQSPNPRRAHAVPPTLVPLVNGSA-----ALGLSGRAAATLAAVSGTPG--LG-AQPAELGTHKRPASVSS-AAAEHEAREQSKEKAQP---AHRSPADSLSGTTGASELSAESAGKGRAPGEQDWASRPKTVRDTLLALHHQHGHSGPFESK-FKKEPALTAAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTST-EGLKIPITPTSSFVSPPPPTASPHSNRTTPPEA----------------------------------------------AQNGQSPMAALILVADNAGGSHASKDT-TQVHSTT-----RRNSSSPPSPSSMNQRRLGPREVGGQATGSTGGLEP---VHPASLPDSSLA-ASAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASG-EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q1P8-1", "uniprot_id": "I2BP2_MOUSE", "id": "E9Q1P8-1", "name": "Interferon regulatory factor 2-binding protein 2", "aln": "MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHGCFPEGRSPTGAQP-AAAKPPPLSAKDLLLQPPPQLGHAGAEAAR--AQAMERYPLAP--DRAPRLASDF-STRAGAGLPQSAAQQSAPANGILVPNGFSKLEEPPELNRQSPNPRRAHAVPPTLVPLVNGSA-----ALGLSGRAAATLAAVSGTPG--LG-AQPAELGTHKRPASVSS-AAAEHEAREPSKEKAQP---AHRSPADSLSSAAGASELSAEGAGKGRAPGEQDWASRPKTVRDTLLALH-QHGHSGPFESK-FKKEPALTAAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGETQPWLSTST-EGLKIPITPTSSFVSPPPPTASPHSNRTTPPEA----------------------------------------------AQNGQSPMAALILVADNAGGSHASKDA-TQVHSTT-----RRNSSSPPSPSSMNQRRLGPREVGGQATGSTGGLEP---VHPASLPDSSLA-ASAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASG-EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z5L9-1", "uniprot_id": "I2BP2_HUMAN", "id": "Q7Z5L9-1", "name": "Interferon regulatory factor 2-binding protein 2", "aln": "MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTLLALH-QHGHSGPFESK-FKKEPALTAG-RLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTST-EGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEA----------------------------------------------AQNGQSPMAALILVADNAGGSHASKDA-NQVHSTT-----RRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGLEP---VHPASLPDSSLA-TSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASG-EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZT6-1", "uniprot_id": "I2B2A_DANRE", "id": "Q6NZT6-1", "name": "Interferon regulatory factor 2-binding protein 2-A", "aln": "--MSSAAVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARQLKRAHG-FQDGRP--------AGPGKQLPGKEIHAS-------GDPGSRP--PQPLDRYPLSS--ERPPRLGAEYQSARQANGIP--------------VPNGFSKPDDPPELNRQSPNPRRTSGVPPNLVPLVNGSMA----------------HAMNGRPG------QMSDLGGNKRPASVSS--------TEHDKDKHRP---------DSLTP----------EISDGHKTRADDWLNKNKTVR-ELMTLN-------PYDGR-FKKEH--MQQRVMYETGP-ASKSDRGKHPKNLKRKASPEPDGEGTAGKINGDGQQWLPSASGDGLKMPPVPPPSFTS-PPSTISPHP-RTTPPEAGAA----------------------------------------AAATQNGHSPIAALILAADNAGGNSSPKDA-NQVHSTT-----RRNSNSPLSP---NQRRL---AQGA-GTPHVPGMD---AVHPQSIPDSSVP-SSIPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRESIKQQGATG-EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7T2G1-1", "uniprot_id": "I2B2B_DANRE", "id": "Q7T2G1-1", "name": "Interferon regulatory factor 2-binding protein 2-B", "aln": "--MSSAAVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARQLKRAHG-FQEGRS--------PGP-VGKPGKDMQSIN-----HAEPGSRP--PQPLDRYPLTS--DRPPRLGAEYQ--RQANGIP--------------VPNGFPKPDEPPELNRQSPNPRRTGAIPPNLVPLVNGSMPP--------------VHALNGRSV------QMGIPPGALAEHVGKR--------ADDMKDKHRA---------DSMS-----------DPSDGHK-RVDEWTQKGKTVR-EMMTLQ-------TLDSR-FKKEHAALPHRMSYESSSGALKTDRGKHSRGIKRKTSPEPDGEGIAVKLNGEGQPWLPSPS-EVLKMPSAALPGFAAAPPSTISPHS-RTTPPEA-------------------------------------------ATAVQNSQSPMAALILAADNAG-TGSPKDAGNQVHSTTTSAAGRRNSGSPQSPS-AGQRRP---ALGATGTAHIPGMDPQ-AGHPHSIPDSSVPPSSVPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRESIKQQGATG-EVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z143-1", "uniprot_id": "B7Z143_DROME", "id": "B7Z143-1", "name": "", "aln": "------MSLQTKRQHCYLCDLPRMPWAMINDFSEAVCRGCVNYEGADRIEAVLDAARQMKRLHPASKQQRSHENGEVSAAAAAAVVLQQQQQLQVGPVPGQGPGSHRGGGGGGPPGAPPGS--GGPGPSGAGSLSSLGNAVAAAAAAAAVHHHHQMPYQMPVPRIGPPLDYPVKLEDAPGGGVRPVRISHMTPHHLPPNATRGGGGAPGGGVPTAGSGGGS------LPPALSVNLKRPPSEDVDVDVSQQQQQSGHGLAP----DGSAGNSLSAGGGVSGGCPPGIKRSAMDDPSGVGGRPPLTRGESLPAAVSYVPERQLSGLRDKQQPVRAPSFDASTFKAANPIPNPIPHHLHIAEHMSPASRRNGSSPPSGPLPPRSVHSPNSSGSSSGRRSSGSRHVSSTTVTSSEVGGSNPGQAVVAGGLGGGGGGGPGSNAASGQLGGPSGGSGQLSCTSGGPGGSASSGSGGNGAIGPASMAPNSVAGDGSPAGGNGPSGSNGSGGSVNPGPGSSGSQGGGGGGTPLASGGGSAGSGGLGGAPGSSAASNSAAAAAAAAAQNATLKCTLCQERLEDTHFVQCPSVNHHKFCFPCSRESIKRQNGLGNEVYCPSGDRCPLANSVIPWAFMQGEITTILGEEVKVKKERES", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::** ************** **:*.*************:* *:::***:** * : *. .. :: . * . . .: . ..: * : : :. * : : * .* . : . . :*:: . . : .* :. .. *:: . . .: ** . : . . : :.. . . . . .... *.. :.* :* ...:..:.. :..:... :. . *. . ...*. * . *. .: * : . :: . . .* ****:************** *********:***:*.. * *******::***..* :*********:***. :*******:.", "identical_positions": 122, "similar_positions": 124, "identity": "18.83%" }, { "cls_id": "homologset.agr.MGI:2443925", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LPD7-1", "uniprot_id": "F1LPD7_RAT", "id": "F1LPD7-1", "name": "Thrombospondin type-1 domain-containing protein 7B", "aln": "-MFPRSDLAVTHWVSRSMRKVFLVLSLLLSQAAHLEGRKDNQFIWKTGPWGRCAG-DCGPGGTQSRAVWCFHIEGWTSPMANCDESSRPPKERSCFRVCDWHSDLFQWEVSDWHRCLLVPGAQGEPRPRAVECVTAQHGLQHRTVRCLQKLNRTMVASEICEHFVPQPPTEQACLIPCPRDCVVSEFSPWSTCPEGCGKKLQHRTRVAIAPPLYGGLQCPNLTESRAC----EAPISCPLGKEEYSFSLKVGPWSKCRLPHLKEAELGGRNVQDFSS-DSNEQVTLTHQSYKAQHHSQ----------PGAIEIGFQTRQVWCTRSDGRNALLSLCMRDSFPLTVQPCVMPKDCETSEWSPWSPCSKTCRSGTLSPGVRSRSRNVKHIAIGGGQECPELLEKETCIAEGEFLQPCPRYSWRTSEWKECQVSLLLEQQDPLWHKTGPICGGGIQTREVYCAQSFPATITSRTK-----EVSRPVESTLCLGPAPSASQLCNVPCSTDCIVSSWSAWGPCVYENCHDPQGKKGFRMRQRHVLMESTGPVGHCPHLAESVPCEDPMCYRW-LASEGICIPDHGKCGLGHRILKAVCQNERGEEVSGGLCPVPPPPERMACEIPCRMDCVVSEWTVWSSCSQSCSNKNSDGKQTRSRSIVALAGEGGKPCPGSQELQEYRLCNDHSCAQLYWETSAWGSCSENTLV--TALNMSIGWNGEATCGVGIQTRKVFCIKSHVGQVMTKRCPESTRPETVRPCFLPCKKDCLVTAFSEWRPCPWPCQPGNTTIK-QSRYRIIIQEAANGGQECPDTLFEERECEDISLCPTYRWKPQKWSPCILVPESIRQGRTGTSEACGKGLQTRDVSCISDDNQSAEMTECLRQMNGMPPLVQECTIACREDCTFTPWSKFTPCSKNCEATQIRRRQLTGKSRKKERCQDASLYPLVELEPCPCDAFMSHPYGNWSACILPEGKRDP---------QQGGLWVQGD-----DKECGEGVRFRAIACTDINGRPVDPSFCNSSGYIQEACVIPCPFDCKLSDWSSWGSCSSSCGIGVRIRSKWLKEKPYSGGRPCPKLDLKNQAQVHEAVPCYSECDQYSWVVEHWSPCKIN--NELRSPR------CGRGTQSRRIRCVS-TADREGGAVDRSLCNQDDAPPETQACSLLCPSECVMSEWGTWSKCPQSCDPHATQRRTRHLLRPSLNSRTCGEDSQVRPCLLNENCFQFQYNLTEWSTCQLSENISCGQGVRTRLLSCVRSDGKPVSMDHCEERNLDKPQRMSIPCLVECVVNCQLSGWTTWTECSQTCGQGGRMSRTRFIIMPTQGEGRRCPTELTQQKPCPVTPCYSWVLGNWSACKLEGGDCGEGVQVRSFSCVVHNGSIS--HTAVQVEDTLCG---EVPFQEGLQKQLCSVPCPGDCHITPWSEWSKCELTCIDGRSFETTGRQSRSRTFIIQSFENQDSCPQQVLETRPCAGGKCYHYTWKASLWNNNERTVWCQRSDGLNVTGGCSPQARPAAIRQCIPACKKPFSYCTQGGVCGCEQGYTEIMRSSGFLDYCMKVPGSEDKKADVKTFSGKNRPVNSKIHDIFKGWSLQPLDPDGRVKIWVYGVSGGSFLIMIFLVFASYLVCKKPKPHQSTPRHQKPLTLAYDGDLDM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P4U0-1", "uniprot_id": "THS7B_MOUSE", "id": "Q6P4U0-1", "name": "Thrombospondin type-1 domain-containing protein 7B", "aln": "-MFLRSDLAVTHWVSRSMRKLFLVLSLLLSQAAHLEGRKDNQFLWKTGPWGRCAG-DCGPGGAQSRAVWCFHIEGWTSPMSNCDESSQPPKERSCFRVCDWHSDLFQWEVSDWHRCLLVPGAQGEPRPRAVECVTAQHGLQHRTVRCLQKLNRTMVSNEICEHFAPQPPTEQACLIPCPRDCVVSEFSPWSTCPEGCGKKLQHRTRVAIAPPLYGGLQCPNLTESRAC----EAPVSCPLGKEEYSFSLKVGPWSKCRLPHLKEVDLSGRNIQDFSS-DSNEQVTLTHQSYKAHHHSQ----------PGDVVIGFQTRQVWCTRSDGRNALLSLCVRDSFPLTVQPCVMPKDCETSEWSPWSPCSKTCRSGTLSPGVRSRSRNVKHIAIGGGQECPELLEKETCIAEGEFLQPCPRYSWRTSEWKECQVSLLLEQHDPLWHETGPICGGGIQTREVYCAQSLPATIASRTK-----EVSRPVERTLCLGPAPSASQLCNVPCSMDCIVSSWSTWGPCVFENCHDPQGKKGFRMRQRHVLMESTGPMGRCPHLAESVPCEDPMCHRW-LASEGICIADHGKCGLGHRILKAVCQNERGEEVSGGLCPVPPPPERMACEIPCRMDCVVSEWTVWSSCSQSCSNKNSDGKQTRSRSILALAGEGGKTCPSSQELQEYRLCNDHSCTQLYWETSAWGSCSENTLV--TALNVTIGWNGEATCGVGIQTRKVFCIKSHVGQVMTKRCPESTRPETVRPCFLPCKKDCLVTAFSEWTPCPRPCQPGNTTIK-QSRYRIIIQEAANGGQECPDTLFEERECEDISLCPSYRWKPQKWSSCILVPESIRQGRTGTSEACGKGLQTRAVSCISDDNQSAEMTECLKQMNGMPPLVQECTIPCRDDCTFTPWSKFTPCSKNCEATQIRRRQLTGKSRKKEKCQDASLYPLVEMEPCPCDTFMSHPYGNWSACILPEGKRDA---------QQGGLWVQGD-----DKECGEGVRFRAIACSNINGRPVDPSFCNSSGYIQEACVIPCPFDCKLSDWSSWGSCSSSCGIGVRIRSKWLKEKPYSGGRPCPKLDLKN--QVHEAVPCYSECDQYSWVVEHWSPCKIN--NELRSPR------CGRGTQSRRIRCVS-TADREGGAVNRSLCNQDDAPQETQACSLLCPSECVMSEWGTWSRCPQSCDPHAMQRRTRHLLRPSLNSRTCGEDSQVRPCLLNENCFQFQYNLTEWSTCQLSENVSCGQGVRTRLLSCVRSDGKSVSMDHCEQRNLEKPQRMSIPCLVECVVNCQLSGWTTWTECSQTCGQGGRMSRTRFIIMPTQGEGRQCPTELTQQKPCPVTPCYSWVLGNWSACKLEGGDCGEGVQVRSFSCVVHNGSIS--HTAVPVEEALCG---EVPFQEGILKQLCSVPCPGDCHITPWSEWSKCELTCIDGRSFETTGRQSRSRTFIIQSFENQDSCPQQVLETRPCTGGKCYHYIWKASLWNNNERTVWCQRSDGLNVTGGCSPQARPAAIRQCIPACKKPFSYCTQGGVCGCEKGYTEIMRSSGFLDYCMKVPGSEDKKADVKNLSGKNRPVNSKIHDIFKGWSLQPLDPDGRVKMWVYGVSGGSFLIMIFLVFTSYLVCKKPKPHQSTPRHQKPLTLAYDGDLDM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0I4-1", "uniprot_id": "THS7B_HUMAN", "id": "Q9C0I4-1", "name": "Thrombospondin type-1 domain-containing protein 7B", "aln": "-MFPKSNLTVTCWVWRSMRKLFLLLSLLLSHAAHLEGKKDNQFIWKPGPWGRCTG-DCGPGGVQSRAVWCFHVDGWTSHLSNCGESNRPPKERSCFRVCDWHSDLFQWEVSDWHHCVLVPYARGEVKPRTAECVTAQHGLQHRMVRCIQKLNRTVVANEICEHFALQPPTEQACLIPCPRDCVVSEFLPWSNCSKGCGKKLQHRTRAVIAPPLFGGLQCPNLTESRAC----DAPISCPLGEEEYTFSLKVGPWSKCRLPHLKEINPSGRTVLDFNS-DSNERVTFKHQSYKAHHHSK----------SWAIEIGYQTRQVSCTRSDGQNAMLSLCLQDSFPLTVQSCIMPKDCETSQWSSWSPCSKTCRSGSLLPGFRSRSRNVKHMAIGGGKECPELLEKEACIVEGELLQQCPRYSWRTSEWKECQVSLLLEQQDPHWHVTGPVCGGGIQTREVYCAQSVPAAAALRAK-----EVSRPVEKALCVGPAPLPSQLCNIPCSTDCIVSSWSAWGLCIHENCHDPQGKKGFRTRQRHVLMESTGPAGHCPHLVESVPCEDPMCYRW-LASEGICFPDHGKCGLGHRILKAVCQNDRGEDVSGSLCPVPPPPERKSCEIPCRMDCVLSEWTEWSSCSQSCSNKNSDGKQTRSRTILALAGEGGKPCPPSQALQEHRLCNDHSCMQLHWETSPWGPCSEDTLV--TALNATIGWNGEATCGVGIQTRRVFCVKSHVGQVMTKRCPDSTRPETVRPCFLPCKKDCIVTAFSEWTPCPRMCQAGNATVK-QSRYRIIIQEAANGGQECPDTLYEERECEDVSLCPVYRWKPQKWSPCILVPESVWQGITGSSEACGKGLQTRAVSCISDDNRSAEMMECLKQTNGMPLLVQECTVPCREDCTFTAWSKFTPCSTNCEATKSRRRQLTGKSRKKEKCQDSDLYPLVETELCPCDEFISQPYGNWSDCILPEGRREP---------HRG-LRVQAD-----SKECGEGLRFRAVACSDKNGRPVDPSFCSSSGYIQEKCVIPCPFDCKLSDWSSWGSCSSSCGIGVRIRSKWLKEKPYNGGRPCPKLDLKN--QVHEAVPCYSECNQYSWVVEHWSSCKIN--NELRSLR------CGGGTQSRKIRCVN-TADGEGGAVDSNLCNQDEIPPETQSCSLMCPNECVMSEWGLWSKCPQSCDPHTMQRRTRHLLRPSLNSRTCAEDSQVQPCLLNENCFQFQYNLTEWSTCQLSENAPCGQGVRTRLLSCVCSDGKPVSMDQCEQHNLEKPQRMSIPCLVECVVNCQLSGWTAWTECSQTCGHGGRMSRTRFIIMPTQGEGRPCPTELTQEKTCPVTPCYSWVLGNWSACKLEGGDCGEGVQIRSLSCMVHSGSIS--HAAGRVEDALCG---EMPFQDSILKQLCSVPCPGDCHLTEWSEWSTCELTCIDGRSFETVGRQSRSRTFIIQSFENQDSCPQQVLETRPCTGGKCYHYTWKASLWNNNERTVWCQRSDGVNVTGGCSPQARPAAIRQCIPACRKPFSYCTQGGVCGCEKGYTEIMKSNGFLDYCMKVPGSEDKKADVKNLSGKNRPVNSKIHDIFKGWSLQPLDPDGRVKIWVYGVSGGAFLIMIFLIFTSYLVCKKPKPHQSTPPQQKPLTLAYDGDLDM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GTI2-1", "uniprot_id": "A0AC58GTI2_DANRE", "id": "A0AC58GTI2-1", "name": "Thrombospondin type-1 domain-containing protein 7A", "aln": "MAFLKEEITFVFSLWAS-----LLYVALMSLSLGAEAPKRSQFMWKTGVWGVCVASDCGSLGLQTRSVWCVHAEGWSTHQSNCFPSDRPAHQRVCVKMCEWQKDLFEWRLSPWGPCTPSPLLPAN------RCVTAQRGVQSRNMQCVKRNNNSSVSLHVCEAFSSAPEGEQACLLPCPMDCVVSAFTHWSTCSRTCGSALQQRTRDVLATPLYGGMDCPSLTQTRPCRHEQGHPALCPSDQQEYSYSLWAGPWSPCR---IKGVAPVGKTTVDFNLGKSTVRTSYTIKRHAEGFHRQNHYDEKGYKVSWEIIIGYQTRQLRCLRSDGKNAMLSLCDHDNSAVNFRSCVMPRDCKVSDWSQWSLCSKTCRTSDPSPGFRHRSRSLIQAAIGGAEPCPVLEEKANCNILEDALPLCPRYEWRVTSWNPCQVTPLLSQQDHRRTNTSVLCGGGMRTREAYCVQIQDNTVPSHSKNTGFDKPSRPVGKNLCTGPLPPLAEFCFIPCQKHCPLTPWSPWGPCLHDNCLEPQGRRGFKIRSRSVITESWVESDSCPHVSEAMTCDDPVCFLWRVASLGPCLPLNGSCGPGLQEQTLECVSASGEPVSNDQCPEDPPAVQRLCEMPCPGDCVLGHWGFWTSCSQSCSSKHQEGKQSRSRLVLALPGDYGKPCPPGSELEQWRSCGAHSCTVYHWDASPWDPCMPNTITDKTERNRTVQMEDDSTCGTGLQTRQVICRRAGNGHVLPKRCPESSRPDSVRSCPLPCKVDCIVTAFSEWSVCPTSCLSVNATVSTQSRHRIIIQRHANGGQECPDTLYEERNCDPPPLCPTYRWQTHRWHQCVLVPDSVRQAVGGPAEACGSGLETREVTCVGADDAPAEMAECVSWAGLMPVSVRECRVPCRDECSFTSWSRFSQCRG-CGSWRTRTRSLIGRSKKRWRCQQEELFPLLEKEACPCSEFHSRPQGPWSPCLLSAVKSTAGRPFIQGVFHQGQKAVQDWRGLRRSSECGHGRRYRALVCLDHLRQLVEPALCSSPGYEEESCHVSCSTDCKLSEWSHWSACSASCGGGVKVRSQWLREKPFNGGRPCPKLNSKN--QVSEVLPCYSDCSQYIWEVQSWSVCIINPQNNLTNIRPNHQPVCGEGFRTSKIRCLKRGGENQDEVVDNSLCDLEERPSTAETCLLPCPAHCVTSEWSQWTRCSVDCNDGDLSWRSRSVLRWPEEDHTCPELNQTKPCT-NMACLKYSYVYSDWSSCQLSESAVCGRGIKTRLLNCVRSDGKLVELSLCKELGPSR-GKLSAPCEVACPVNCLITEWSAWSECSHTCGGQSQRSRSRVVLQADSEGGRPCPSQLSQTRPCPIRPCYSWTLADWSPCRVEGADCGEGVSRRERSCVLHWGSLSGPPQPVPVEDEKCVGHLQSKVSEIEFLQPCTVPCPGECHLTQWSPWSSCQLMCLDGRSFETWGRQARSRAVVTQVQENQESCPSQTYETRPCQGGTCLSYEWMTGEWRHNRRLVWCQRSDGVNVTGGCMAVNQPSAVRQCQPPCTKPFSFCTQNGVCGCEKGFTEVMTSHGFLDYCTRTPGLDHKKADVKSTAGRLRPDYTRNNKHVKDWTLQPLGPDGRVKLWVYGLMAAGFVVILLLIVMSFLLCKNPEDSPSSSP-QKALALAYDGDMDM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.:::.. : * *: *:* : *. * .**:**.* ** *.. ***. * *:*:***.* :**:: :** *.:*.::* *.::*:*:.***:*.:* * * * .: .*****:*:* * ::*::: *.: *: .:** * * *****:*** ***** * **.*.. **. **:*** .:*.**:**::**.**::*.* * ** .::**::** .**** ** :* *:. **. .*. :.: . : : .* : . : **:****: * ****:**:**** :*. .:..:.*:**:**:.*:** ** ******:. **.* ***.: : ****.: ** * ** * : * ****.**.:.*: ***: **.*:* *. :****::***.**.* : . ::* : **** ** ** * :::* :**. .* ::.**.** *:.:** :***::**: *.* *: ** . ***: *::.*:**:*. * :** * *:. :*.** * : . * . ** **.. ** **. : **:** ***:..* *:*******.*:.:***:*** ::**.*: **.** .. *:: * *. *** :*::*.*..* :*:. * * :: :.::***.*:***:*:* :: *:*:.****:*:**::**.* **** **:******* ** * . *:*:. ***:*****. ***********:***:*: .*** ***:.::* *:***:*: *. *.:****.**:** *:*:. *: .*** **: . ** *:** :.**::*:**.**:*: * * : : * *.* *:*:*: :**: .*:**:* * ***. * *:* * ** *:*. : . ::* ** ..***.* *:**:.* : : *:*::*.*.** :* * :.*. *****:** *.:**:*** **::**:**:***:.********: ** ** *.:****:*.** * *: ** * ** *:* . * ** * :: :***:. .: :. .*: .**: :: * :::* * ** .** ***. *::*. .*: . *:* :** . :.:** * .*.:** * *:::.* ::**:*****. **:*::****.** **** *.:. *:: . .: ::* ** * * *** :: *::*:***:*** .: **:*.:: . . ** **::*:* :.**: *****.*.:**.*::**.******. *. **::* **:* . **: * : ..: * *:*****:**:* ** **.*:* *:******* ***:***:.: * ***:***.*. ***** **.* * * :. *.:*.* ********:****** . :*:*:*** *.* ****:***.******:*:**:* * ****** :.** :.******. :*: ** :: :. .*.*:****.******:****: ...*:::::*:. *:*:**:*: *:. **.*:******:**", "identical_positions": 744, "similar_positions": 479, "identity": "44.74%" }, { "cls_id": "homologset.agr.MGI:2443926", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PNC0-1", "uniprot_id": "DMXL1_MOUSE", "id": "Q6PNC0-1", "name": "DmX-like protein 1", "aln": "MNLHQVLTGAVNPGDHCFAVGSVGEQRFTAYASGCDIVILGSNFERLQIIPGAKHGNIQVGCVDCSMQQGKIAASYGNVISVFEPVSLPKKRKN--LEFYSQWQKSGQFFLDSIAHNITWDPAGNRLLTGSSCLQLWC--NSRKQTEDENP----------------DKTDLNFGNWMCIWHCKTASQVHLMKFSPDGEFFATAGKDDCLLKVWYN-------VENWRPAVTSP------DKNSEKQSQGEIDFSFVYLAHPRAVNGFSWRKTSKYMPRA-SVCNVLLTCCKDNVCRLWVETFLPNDCFLYGSDCN-----------------------HWCEPVSLTNNLKRNASSKDRVQSALEVN----LRPFRRGRSRSLALVAHTGYLPHQQDPHHAHRNTPLHAN-----ALCHFHIAASINPATDIPLLPSITSLSLNENEEKCGPFVVHWLNNKELHFTLSMEVFLQQLRKSFEQPSSEASVEDSIQADLKSDEE--------------------LDDGVDDLKINHEKKE------------LDEDKMLPSSSFTPLSS----------AAVDHQIEVLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMFRQVQVSFVSRIPVAFPTGDANSLCKSIVMYACTKN--------------------------------------------VDLAIQQGKQRPTG----------LTRSTSMLISSAHSKSSNNLKLS-------IFTPNVMMISKHADGSLNQWLVSFAEES-AFSTVLSISHKSRYCGHRFHLNDLACHSVLPLLLTTSHHNALRTPNVGNQKQAHDAVN-----TEECSLAQQNKSNVDMAFQDPNAIYSELILWRVDPVGPLSFSGGVSELARINSLHVSAFSNVAWLPTLIPSYCLGAYCNSPSACFVASDGQYLRLYEAVIDAKKLLYELSNPE----------ISKYVG--------------EVFNIVSQQSTARPGCIIALDSITKLHG--RKTQLLHVFQEDFILN----------NLEKKRLG----VDNILLDSDSSCNGFSEKFYLVVIECTEDNRSLLRMWDLHLRSTPVS---LDERIDTKISEASWLPEEHYS--SSPEKILSPFSQKFQACRAN--LQSTSKLSLFSEMVYSKELDLPEGVEIISVKPSAGHLSSSSIYPVCSAPYLLATSCSDDKVRFWRCRVTNGESATSKNGKLDVVYVWEEWPLLIEDGLENNSSVTVPGRPVEVSCAHTSRLAVAYKQPTGNSRS--------QEFVMHVSIFECESTGGSCWILEQTIHLD-------------ELSTVLDSGISIDSN-------------------------LVAYNKQETYLVS--------------KESITSN-------TKHLVHLDWMSREDGSHILTVGIGSKLFMYGPMAGKVQDQTGKENQ-----------AFPLWDSTKIVPLSKFVLLRSVDLVSSVEGAPPFPVSLSWVRDGILVVGMDCEMHVYSQWQPSNKQEPVISESYNGSTP--------------------------SILSLIKQSNSSSSGLHPPKKTLTRSMTSLAQK----ICGKKSIFDPSVD-------MEDSGLFEAAHVLSPTLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIAG-EVVALNEAESNHERR---LRSLTISASGSTTRDPQAFNKADSR--------DYTEIDSVPPLPLYALLAADDDSYCSSLEKTGSESSLKKSKQLSKESYDELFQTSVLMS--DNHMLETDEENTQPRVIDL-SQYSPTYFGPEHAQVLSGHLLHSSLPGLTRMEQMSLMALADTIATTSTDIGESRDRNQGG--------------------ETLDECGLKFLLAVRLHTFLTTSLPAYR-AQLLHQGLSTGHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNARILRRCIEKVAKAAFHR--NNDPLDAAIFYLAMKKKAVIWGLYRSQK----DTKMTQFFGHNFEEERWRKAALKNAFSLLGKQRFEHSAAFFLLGGCLKDAIEVCLEKLNDIQLALVIARLFESEFDKSATYKSILRKKVLGIGSPASELSSSSINAHHDPFLRSMAHWILEDYSAALETLIKQPVT--------EDEDQVMMSACNPIVFNFYNYLRTHPLLLRRHFGSSS-----------------ETFSTHMTLAGKSGLAGTINLSERRLFFTTASAHLKAGCPMLALEVLSKMPKVSKKAKPCCRGSSFLTS----KDSS-LKLDVREDKCCAADWSPSLTNGLESSSEGSSERHSHSTLSFDWSQPSVVFQDDSLELKWDSDNDEENEDPPISMKEIRPLQRKTVKEIDELSS-YTDSLSTLDENDILNPSEDIIAVQLKFRACLKILTVELRTLSTGYEIDGGKLRYQLYHWLEKEVVALQRTCDFCSDADQLQTTFSQSADESGSTEDADDLHHQTKVK-QLRESFQEK-------------RQWLLKYQSLLRMFLSYCVLHGSHGGGLASVRMELILLLQESQQETAEPIFSNPLSEQTSVPLLFACTASAKTVVANPLLHLSNLTHDILHAIINFDSPPHPD-SQTNKVYVMHTLAASLSACIYQCLCGS----HNYSSFQTNQFTGMVYQTVLLAHRHS------------LRTGSLDESVTPNTSPAQWPGINFLIQLLNSSGEEAQSGLTVLLCEILTAVYLSLFIHGLATHSSNELFRIVAHPLNEKMWSAVFGGGAHVPSKGQANSKALS--------------------------------------VEGEKQN----------RHISPSKVSARES-PVSSSSG--NQEPPAVKEKFVPPELSIWDYFIAKPFLPPSQSRAEYDSEESLESDDEEEEDDDD---------ALPSGLQLHEHSNSNSFSWSLMRLAMVQLVLNNLKTFYPFAGHDLAELPVSSPLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYISSHTSEENVSAGPAILRHKALLEPTNTPFKSKNHLALSVKRLWQYLVKQEEIQETFIRNIFTK---------KRCLNEIEADLGYPGGK------ARIIHKESDIITAFAVNRANRNCIAIASSHDVQELDVSAILATQIYTWVDDDTETETK--------GSEDFLVIHARDDLSAVQGSTPYTHSNPGTPINMPWLGSTQTGRGASVMLKKAINNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFR-SGGNSRITRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPYLAWQCHNKTANDFVFVSSSSLIATAGLSSDNRNICLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCIFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTFINEHARQSIFRNIGTGVMQIETGPANHIFSCGADGTMKMRILPDQFSPLNEVLKNDVKFML", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZU67-1", "uniprot_id": "A0A8I5ZU67_RAT", "id": "A0A8I5ZU67-1", "name": "DmX-like protein 1", "aln": "MNLHQVLTGAVNPGDHCFSVGSVGEQRFTAYASGCDIVILGSNFERLQIIPGAKHGNIQVGCVDCSMQQGKIAASYGNVISVFEPVSVPKKRKN--LEFYSQWQKSGQFFLDSIAHNITWDPAGNRLLTGSSCLQLWCNINSRKQTEDENA----------------DKTDLNFGDWVCIWHCKTASQVHLMKFSPDGEFFATAGKDDCLLKVWYN-------VENWRPAVTSP------DKNSEKQSQGEIDFSFVYLAHPRAVNGFSWRKTSKYMPRA-SVCNVLLTCCKDNVCRLWVETFLPNDCLLYGSDCN-----------------------HWCEPISLTNNLKRNASSKDRVQSALEVN----LRPFRRGRSRSLALVAHTGYLPHQQDPHRVHRNTPLHAN-----ALCHFHIAASINPATDIPLLPSITSLSLSVNEEQCGPFVVHWLNNKELHFTLSMEVFLQQLRKSFEQPSSEASVEDSIQADVKSDEE--------------------MDGGVDDLKINHEKKE------------LGEDKMLPSSSFTPLSS----------AAIDHQIEVLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMFRQVQVSFVSRIPVAFPTGDANSLCKSIVMYACTKN--------------------------------------------VDLAIQQGKQKPTG----------LTRSTSMLISSGHSKSSNNLKLS-------IFTPNVMMISKHADGSLNQWLVSFAEES-AFSTVLSISHKSRYCGHRFHLNDLACHSVLPLLLTTSHHNALRTPNVGNQKQAHDTIN-----IEECSLAQQNKSNVDMAFQDPNAVYSELILWRVDPVGPLSFSGGVSELARINSLHVSAFSNVAWLPTLIPSYCLGAYCNSPSACFVASDGQYLRLYEAVIDAKKLLYELSNPE----------ISKYVG--------------EVFNIVSQQSTARPGCIIALDSITKLHG--RKTQLLHVFQEDFILN----------NLEKKRLG----IDSILLDSGSSRNGFSEKFYLVVIECTQDNRSLLRMWDLHLRSIPVS---LDERIDTKISEAIWLPEEHYS--SSPEKILSPFSQKFQACRAN--LQSTSKLSLFSEMVYSKELDLPEGVEIISVKPSAGHLSSSSIYPVCSAPYLLATSCSDDKVRFWRCRVTNGESATSKNGKIDLVYIWEEWPLLIEDGLQSNSSITVPGRPVEVSCAHTNRLAVAYKQPTCNSRS--------QEFVMHVSIFECESTGGSCWILEQTIHLD-------------ELSTVLDSGISIDSN-------------------------LVAYNKQETYLVS--------------KESITSS-------TKHLVHLDWMSREDGSHILTVGIGSKLFMYGPMAGKVQEQTVKENQ-----------VFPLWDSTKVVPLSKFVLLRSVDLVSSVEGAPPFPVSLSWVRDGILVVGMDCEMHVYSQWQPSYKQEPVIADSYNGSTP--------------------------SILSLIKQSNSSSSGLHPPKKTLTRSMTSLAQK----ICGKKSTFDPSVD-------MEDSGLFEAAHVLSPTLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIAG-EVVALNETESSHERR---LRSLTISASGSTTRDPQAFNKAENR--------DYTEIDSVPPLPLYALLAADDDSYYSSLEKTRNESSLRKSEQLSKESYDELFQTSVLMS--DNHILETDEENTQPRVIDL-SQYSPTYFGPEHAQVLSGHLLHSSLPGLTRMEQMSLMALADTIATTSTDIGESRDRSQGG--------------------ETLDECGLKFLLAVRLHTFLTTSLPAYR-AQLLHQGLSTGHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNARILRRCIEKVAKAAFHR--NNDPLDAAIFYLAMKKKAVIWGLYRSQK----DTKMTQFFGHNFEEERWRKAALKNAFSLLGKQRFEHSAAFFLLGGCLKDAIEVCLEKLNDIQLALVIARLFESEFDKSTTYKSILRKKVLGIGSPASELNSSNINAHHDPFLRSMAHWILEDYSAALETLIKQPVT--------EEEDQGMMSACNPVVFNFYNYLRTHPLLLRRHLGSS------------------DTFSTHMALTGKSGLAGTINLSERRLFFTTASAHLKAGCPMLALEVLSKMPKVNKKAKPFCRGSSFLTS----KESSPLKSETREDKSSAVDWSQSLINGFESSSEGSSERHSNSTFSFDWSQPSMVFQDDSLELKWDSDNDEENEDPPISMKEIRPLQRNTIKELDEFSS-YTDSLSTLDENDILNPSEDIIAVQLKFRACLKILTVELRTLSTGYEIDGGKLRYQLYHWLEKEVVALQRTCDFCSDAEQLQSTFSQSADETGSIEDADDLHHQTKVKQQLRESFQEK-------------RQWLLKYQSLLRMFLSYCVLHGSHGGGLASVRMELILLLQESQQETAEPIFSNPLSEQTSVPLLFACTASAKTVVANPLLHLSNLTHDILHAIINFDSPPHPD-SQTNKVYVMHTLAASLSACIYQCLCGS----HNYSSFQTNQFTGMVYQTVLLAHRHS------------LRTGSLDESVTPNTSPAQWPGINCLIQLLNSSGEEAQSGLTVLLCEILTAVYLSLFIHGLATHSSNELFRIVAHPLNEKMWSAVFGGGAHVPSKVQTTSKALSGRHFAMPSPHQVVVFSMECVGFSKALSAISSHSPPTLAVEGEKQN----------KHISPSKVSGRESSPVSSSSV--NQEPLAVKEKFIPPELSIWDYFVAKPFLLPSQSRAEYDSEESLESDDDNDDDDDDDDDDDNDDDTLPSDLQLHEHSNSNSFSWSLMRLAMVQLVLNNLKTFYPFAGHDLAELPVSSPLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYISSHTSEENVSAGPAILRHKALLEPTNTPFKSKNHLALSVKRLWQYLVKQEEIQETFIRNIFTK---------KRCLNEIESDLGYPGGK------ARIIHKESDIITAFAVNKANRNCIAIASSHDVQELDVSGILATQIYTWVDDDTETETK--------GSEDFLVIHARDDLSAVQGTTPYTHSNPGTPINMPWLGSTQTGRGASVMLKKAINNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFR-SGGNSRITRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPYLAWQCHNKTANDFVFVSSSSLIATAGLSTDNRNICLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCVFDLRQRQQRQLFQSHDSPVKAVAIDPTEEYFVTGSAEGNIKIWSLSTFSLLHTFINEHARQSIFRNIGTGVMQIETGPANHIFSCGADGTMKMRILPDQFSPLNEVLKNDVKFML", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y485-1", "uniprot_id": "DMXL1_HUMAN", "id": "Q9Y485-1", "name": "DmX-like protein 1", "aln": "MNLHQVLTGAVNPGDHCFSVGSIGDQRFTAYASGCDIVILGSDFERLQIIPGAKHGNIQVGCVDCSMQQGKIAASYGNVISIFEPVNLPKQKKN--LELYSQWQKSGQFFLESIAHNITWDPTGSRLLTGSSYLQLWSNTNLEKPTEDENL----------------NKTDLNFGDWKCIWHCKTASQVHLMKFSPDGEFFATAGKDDCLLKVWYN-------VENWRTAVTSP------DGSSEKQSQGEIDFSFVYLAHPRAVNGFSWRKTSKYMPRA-SVCNVLLTCCKDNVCRLWVETFLPNDCLLYGGDCS-----------------------HWTESINLTNNFKRNASSKERVQNALEVN----LRHFRRGRRRSLALVAHTGYLPHQQDPHHVHRNTPLHAN-----ALCHFHIAASINPATDIPLLPSITSLSLNENEEKTGPFVVHWLNNKELHFTLSMEVFLQQLRKSFEQPSSEASVEDSNQADVKSDEE--------------------TDDGVDDLKINPEKKE------------LGCDKMVPNSSFTSLSS----------AAIDHQIEVLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMFRQVQVSFVSRIPVAFPTGDANSLCKSIMMYACTKN--------------------------------------------VDLAIQQGKQKPSG----------LTRSTSMLISSGHNKSSNSLKLS-------IFTPNVMMISKHADGSLNQWLVSFAEES-AFSTVLSISHKSRYCGHRFHLNDLACHSVLPLLLTTSHHNALRTPDVDNPEQPFDALN-----IEECSLTQQNKSTVDVAFQDPSAVYSELILWRVDPVGPLSFSGGVSELARINSLHVSAFSNVAWLPTLIPSYCLGAYCNSPSACFVASDGQYLRLYEAVIDAKKLLSELSNPE----------ISKYVG--------------EVFNIVSQQSTARPGCIIALDPITKLHG--RKTQLLHVFEEDFILN----------NLEKKSLG----KDSILSNAGSSPNGFSEKFYLIVIECTQDNRSLLHMWNLHLKSIPVS---LDEKVDTKLSEAVWQPEEHYS--SSPEKILSPFSQKYQACRAN--LQSTSRLTLFSEMVYSQELHLPEGVEIISIKPSAGHLSSSSIYPACSAPYLLATSCSDEKVRFWRCRVTDGESATSKNGKIDLAYIWEEWPLLIEDGLQSNSSITVPGRPVEVSCAHTNRLAVAYKQPASNSRSS-------QDFVMHVSIFECESTGGSCWVLEQTIHLD-------------ELSTVLDSGISVDSN-------------------------LVAYNKQDMYLSS--------------KENITSN-------TKHLVHLDWMSREDGSHILTVGIGSKLFMYGPLAGKVQDQTGKETL-----------AFPLWESTKVVPLSKFVLLRSVDLVSSVDGSPPFPVSLSWVRDGILVVGMDCEMHVYCQWQPSSKQEPVITDSYSGSTP--------------------------SITSLIKQSNSSS-GLHPPKKTLTRSMTSLAQK----ICGKKTAFDPSVD-------MEDSGLFEAAHVLSPTLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIAG-EVVALNEAESNHERR---LRSLTISASGSTTRDPQAFNKAENT--------DYTEIDSVPPLPLYALLAADDDSCYSSLEKSSNESTLSKSNQLSKESYDELFQTQLLMT--DTHMLETDEENTKPRVIDL-SQYSPTYFGPEHAQVLSGHLLHSSLPGLSRMEQMSLMALADTIATTSTDIGESRDRSQGG--------------------ETLDECGLKFLLAVRLHTFLTTSLPAYR-AQLLHQGLSTSHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNTRILRKCIEKVAKAAFYR--KNDPLDAAIFYLAMKKKAVIWGLYRAEK----NTRMTQFFGHNFEDERWRKAALKNAFSLLGKQRFEHSAAFFLLAGCLRDAIEVCLEKLNDIQLALVIARLYESEFDTSAAYKSILRKKVLGIDSPVSELCSLNINMHHDPFLRSMAYWILEDYSGALETLIKQPIR--------ENDDQ-VLSASNPTVFNFYNYLRTHPLLLRRHFGSS------------------DTFSTHMSLTGKSGLAGTINLSERRLFFTTASAHLKAGCPMLALEVLSKMPKVIKKTRPFYRASSFLDTSKDCSPSSPLKLDAREDKSSAVDWSQSLINGFGSSSEGSSEKQSNSTLSFDWSQPSVVFQDDSLELKWDSDNDEENEDVPISMKELKPLQRKTDKKLDDISSNYTESFSTLDENDLLNPSEDIIAVQLKFRACLKILTVELRTLSTGYEIDGGKLRYQLYHWLEKEVIALQRTCDFCSDAEELQSAFGRNEDEFGLNEDAEDLPHQTKVK-QLRENFQEK-------------RQWLLKYQSLLRMFLSYCILHGSHGGGLASVRMELILLLQESQQETSEPLFSSPLSEQTSVPLLFACTANAKTVVANPLLHLSNLTHDILHAIINFDSPPHPD-IQSNKVYVMHTLAASLSACIYQCLCGS----HNYSSFQTNQFTGMVYQTVLLPHRPS------------LKTGSLDEALTPNTSPAQWPGITCLIRLLNSSGEEAQSGLTVLLCEILTAVYLSLFIHGLATHSSNELFRIVAHPLNEKMWSAVFGGGAHVPSKEQTHSKTLP---------------------------------VSSLVEEGEKQN----------KRFRPSKMSCRESAPLTPSSAPVSQESLAVKEKFIPPELSIWDYFIAKPFLPSSQSRAEYDSEESLGSDDDDNDDDDD---------VLASDFHLQEHSNSNSYSWSLMRLAMVQLVLNNLKTFYPFAGHDLAELPVSSPLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYIASHTAEESLSAGPAILRHKALLEPTNTPFKSKHHLALSVKRLWQYLVKQEEIQETFIKNIFTK---------KRCLNEIEADLGYPGGK------ARIIHKESDIITAFAVNKANRNCIAIASSHDVQELDVSGILATQVYTWVDDDIEVETK--------GSEDFLVIHARDDLTAVQGTTPYTHSNPGTPINMPWLGSTQTGRGASVMIKKAINNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFR-SGGNSRVTRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTGVMQIETGPANHIFSCGADGTMKMRILPDQFSPLNEVLKNDVKFML", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W425-1", "uniprot_id": "Q9W425_DROME", "id": "Q9W425-1", "name": "", "aln": "MNCHQILSGACNAGDRCFAIGSVEGIPFTAYAAGCNVVILASTFERVQIIPGANHGYVKISALDCSTDTGKIAAAYENKICIFEPTPVIESSKHNTHFLDYRWVQTGSFTSHSNVVTLSWNLEGTRLLTGGTNIQLWKSKSPTHQQEEEHTGVKFEIGESKEPKQTSNAQSEDVSTWENIWSCQTAIPIYHMAFSPDGTLFATCGRNDRLVKIWYENKQVLFPAKGSSNAGPTPSCRHGVDDGTTSSSGGELNFTYVYIAHPRAVSNIVWRKTSKYMPKG-SVANMLVTSCLDNICRIWIETVLPDDGMVNMTQFDPMASQNPKFRTHRHKHRFMQRLKHMKTCFHIRRHMKAGASAVPGAASAGAASGGGTAGAMGGMGSSPASYTNYLGPIPSLPSSCSVHDFHSYGFQGSGVTPGMHFHLAASINAETDIPLVPSMQTSDPANQN----VFILHWLNNKEMHFTLQAEAILQELTKKVIDEENGHGNASSGGVDLPDDAHGSHSQAHAHKKYLRSSKSVSVDDSGEEFSRYSQHTAGTGMGGGGGGAGLHLNSMSNTTSQNSLNNEPAHPITQLVDSLDNKIECLLRDWHQSPDLLFAIHPVDGSYLIWVIEWLDDYYPGSFRQAQVSFSTRIPSAFPLGDAMSMSTTVSLFNTGTHPLAFRDIANNVRSKDEFHKGHADDSSLKSDQHSGQTFERHDEEQEDAADDDGDGDREGDADQDEGGGDRSAAASGGGAAEHSSSSQDSAATGASALPLNVSPSVSMVTKHSNGTLNLWQLTFAFKT-KFTQVLSIGHVSRASGHRFRVNDITCHPVLPLLVSTSHHNLPDSEAKSPMSLFEQPLSGGLPSGGGTGAGPSVGSNGDKDVFTPTGFCSELILWRVDSVGPLCHSGGVSELARINSPEISAFSNVAWIPTLLPSTTLGSYSNSPSACFVASDGENLRVYQAVIDARTLLAEISCSENLNTLHKSHSLSSMISNASSTMRAQRSALHDKLKVVSQQSTARPGCILQLDAISDAKHDWQNTQFLHVFQAQLITGGQRTPQADPHDLEEPRLNALLESDMDAIVDLQRNADFEEPFYIVNIEKTLRG-STIHMWRIVISSKQQSSFLSETAMYVPDSNLTQEPDEDGAGGNPNPRRMSQGAETLTGAEHFGPQVEAPHISITTKKVCTQELPLPEGVDVIHASPAAGHLSSSSIYPACFAPYIIVTACSDSISRFWKCEPIGDEDDPNPEG---DAYHWSEWKMFSR---IQHSAIEIPGQPLNISAAYSGRIACAYKYGKSFTRPNKGPDPDSRYVNLCVAIYECESSGGSEWVLEDTIHLKNVHLPRINIGHGIDLSYLHDSRLLAKKQRLNQVLHTFAHDPESRSPRSGETTPELAVNRQPSAAASGLLTVPSFSTLQSLRKSIAENGNTCPLTQKHLVQLDWVSKEDGSHILTVAVGSKILLYTPVSSDIAQANIKAMKESRSVNRPILRKASSLAQPNFVDEIRWMKLRQIDLQT-ADGLPPLPMQISWVRDGILVVAMDSEMHVYSQWKPHYSSHFAAAAAAAGEDVPDTRNLRDEDLRSLANESTQLRLKNVASMPLISKVSTANLQLLSHDKKRRLGNTSMANMNGAGGAGGTGTYGGGADDGGNDDYMTDFGLFQASRIACPVLPQYHPKQLMELLNCGKIRWVKAILAHLVRCMSGNSSSTVNQDDDGYARQRSWSRSRTLSISYTADQNIQAEHRGSTTQIPEELMLDYAEINSIPPLPLWVLLNADRETPGQSNNYAEGD-----------KDYDELFDMHNSEDNLDELLSEGDEKKRQERRLSLPEKHSISHFGPRQGQLLSRLLTHTHLPGLSSLDQMHLLALADTVATCNTDFSDKFAADQGKSGGMAGGAGSGAVKDGSTSTDSLDDCGLRFLLAMKHFTYLLRCLPLQQRAQFQRQGVGTSNIVWAFHSESEEELLNLIPSYTKGDLRWATLRDLGVGYWLKNINTLRRCVEKLAKCAYQQ--KQEPLDAAIYYLAMKKKSLVWGLFRSRR----DEKMTAFFGNNFAEDRWRKAALKNAFVLLGKQRFEHAVAFFLLANSLNDAIEVCMNKLEDFQLALIIARLYEGDGEG-CYYHHLLHEHILGTDAATGRCDLS--RAHPDPFLRSMTYWTIKKYQESLNTLLLNNVGSLHSSYREEDLLRPEQQATNPNVFNFYIYLRTHPLLIRQNIALSAQEKRIAHVVLSGFNYAGDAAPSAVACDKQLQLEDSITPIERQLYFTTAHGHFKSGCPALALEVLNKLPQKISDDS----GGSVAGS----------QAQERAQQNKEELINTGIMDQWGATPAAAS----NTADAFDWGAPVSSEPEAKFEIKWDDEDEEEDPDLEPDEPELATPQPQ-------------APILGRGKSNGNDTKMDIMAQQLKFVACLKILMEELSTLATGFEVDGGQLRYQLYMWLEREVEALKQLCNYCSQAEQSSHESGDADAEARDKEMNASIYPSTERPTLHEILMQDKQDFEAKVMRAAKRKRWLKANETLLRTLLSYCSLHGASGGGLASVRMELVLLLQELQQEKTQQQLLSPLPFPTTLPLLSACVAGNKTVIADPIKYLQSQTVDMLQSIIKVLPFPGIEPSALSEIFVLRDLAVALSSCIYQSLCDSESFVVNNSAFNGYPSPGMENIAKINSSFECSYLVGSRNAYGRRRKYSTDEPAGVCTTPSKWPGVTNLRALLAREKDEDVPKLNVLLLESFVSTYMALFIYSLSTCDSRLLYRLSGQSFNNETWSTLFGGGMKKLLIKPAAAPPPTQMVTG------------------GAGAGGASGGTGSTSEEPTDENSVWNTVTSITKQRMKLNMKILGSFSQNSTSSNMKEDKPTYREQFMPPETSMLSYFLTK---PPTTECDDYDTDDSHESDNEEEEEDDDDVN---VSRSQLKAKDNTEHTNPTSYSWSILRLALIKISTHKIQELVKVAGIELQDLPVISPLSHEVLRTLNRWQDFALSDLIARGPPSRNYIPGCYAESGING-LAIHKYRSLLNKDNTPFVS-GSSAGPIRRLWNYLVRQEPAQEVFIKSIFVKNMEPSTRGSHHTNNDNETDEGQSHSTNENTDHIRIIHKDHESILSFCLKNNSSSMIAFANPREIQEFDISLLLESPN--WYEDECDYDMMNLSKDADTNSSSFLIIQTQEQNQFGSNSNAYSESNASTQS------ASQSGRGTSMVLRHKVDNVKRMSAHPLMPLYLTGGQDGSVQIWEWGHQQPVCSPRTSGTFAKVTRCRFSEQGNKFGIGDGDGKLSLWQAG-----IASQNNRSFISYQCHNKALSDFVFLGSCSLLASAGQSSENKNINIWDTLLPHKKSCVSAFTCHDQGSSCLVFAPQHQVLISCGKRGDVCVFDVRQRTLRHRYQAHDSTIKCIALDPHEEFFVTGSIEGDIKIWDMNQFMLINTFPHEHAKNGFFKHTGQGVSQVYVDAFGRLFSCGSDGCMKVRLLVEKDNIVHSVY--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47104-1", "uniprot_id": "RAV1_YEAST", "id": "P47104-1", "name": "Regulator of V-ATPase in vacuolar membrane protein 1", "aln": "-MSLNFLPGRPNATPQTACQATWQNHTIFAYCSGNNLIILTNKFTRLQTIYTQSD----CTAVDINSQNGFIALSFHNRVLIYKPIHQIMQNPK--------WTQCCQLFHDDTPVNCLRWSSDNELAIGSDFLSFWKIKDNFG-----------------------------VYQPILQWNQKQPKPVYNVIISQDSQLIVSIGKYDCNAKLWKR----------------------------VSIVGEQAIFNLTMLPHPKPITAMRWKKEPDQVSKNNTASHALYTLCEDKVLRIWSCFEMEKN---------------------------------------------------------------------------------------------------------------------HTVQIWGEVPLSP-------------------------TQKFCVIIDNWIIRQTLSVKDSE---------------------------------------------------------------------------------------------------------IFDISDSDIVILGSMTGEMEVLALNNLSQDPPKPMTKKTISHKKVKKATMLNDTRYLYLPEIQPYDNVKG------------------------------------------------------------------------------------------------------KLSFLVHDLQGVIRHLLIDILQLINNKTEDLSAALEHKFTGHNKSVQKLVRSSDGEALLTTSRFSE----------------------------------------------------------------------------------NGVWYPQKLN------------------HGVSLRLQNTIQTESPIKFAVVHELG----------------------------------KQVICLLENGALQAWECPTNRKEDSEQKQSYLRVETRLK--------------EEKKIHP-----IVMLNTPEPKHSHERHFTALIFSDGSIKAFEVSLTRGIFEVKSDS------------------------------------------------------LDIDGDDIYKISIIDPVHQTFVSNRPLISLITKKGLT----RTYKAIVNYNDRHVQWIKACEINTG-------------------------IMNCTCIRGSSTGKLCIVNSTGKVMSLWDLNRG------------------------------VLEYEETFHNP-------------------------------------------------------------------------------------------------IEDIDWTSTEYGQSIVSIGFTGYALLYTQLRYDYTNNTP-----------------------------SYLPIEKIDITAHTAHN---IGDSVWMKNGTFVVASGNQFYIK----------------------------------------------------------DKSLDLTDPFTYQSIGSRKILSN----------------------------DILHLSSVLNGPLPVYHPQFLIQAIYANKLQLVKELLLRLFLALRKLDFESQDVSNLDSNLG---------------------------------------------MDPLKYFIAKDRDYPVESFP------------------------------------------------------DPYPCFNKTVSLALTEQLTKTTLPYLTRHQQITLITVIEAVDEVTKNE------------------------------NIVDYNGVRFLLGVKLFLSHKN----------IQKSILMRDVSWALHSDNKE---ILLSSIDRHITSWNRAREYRIAYWIK-EQDLVKKFEDIAKYEFSKDDKRDPSRCAIFYLALKKKQILLSLWKMAIGHPEQQKMVRFISNDFTVPRWRTAALKNAFVLLSKHRYMDAAVFFLLTDSLKDCVNVLCKQVHDMDLAIGVCRVYEG--DNGPVLGELLTAQMLPETIKE-----------NDRWKASFIYWKLRKQEVAIKALLTAPID-----------LENNSSIVDKEVCVNRSFLVEDPALLYLYNHLR-----------------------NRNLKYFIGSLNVEAKIECTLILRVTDILCRMGCNYLAVSLVKN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WKFIERNSIPVQKLLKSPTKDRAYSAIGAMASEPISTARMRPSLFDKFGSPSASDIESPNP-----------------------------------------------------KLPNSLLDDFLQPPPNSTSSNSLAQSSSSAPRSILDEFVSPSYSQHKENLTPKAPNDSVGETDNSENRKDKLSKDILDDLSSQKPQKPKKS--------AITKNLLDDFV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*.* *. : . .: : **.:* :::** . * *:* * .. .:* . : * ** :: * : :::* . : * : .: .. . ...* *. :.:* . . * : . :: : :* *. ::.: *: * *:* . . : *. . :.**:.:. : *:* .. :.: :..: * * * *:: *:* : .: ::: ::** * :* : : : . .. : . : . . :. : .: *. : :: *.: * : : :*. . :: . : : . .: :: :. :* :. : : : ** . : **. ::.:. . *::**:.. * .* * : .* **: ::: : : . . . *.: : :. : .:.* .: : *: : . .... * : :. : : : * : : . : . .: * .: * . ::...: .* . .* :: :. . . :.: .. :.:: :. *:*:* : .:** * * *. *:::.. . ::* : . : . :: :..:*: : . . *:::* :**. . :::: . * . . .: . .::. : : ** *** *:: : .*:: .* :* :*. .: . : : : . ** :: * : .* . . *. . *: * :: ** *: :*: *::: ::: ..: : :* *::***.:: . ::.: .. **:** :* ::.: : * * :.:*:: . * : .*.:** : : :.:* .**:***:*** :: .*:: : :*. *:.::* ***.******* **.*:*: .:..**** ..*.*.::* :::.*::**: :.*::*. : :* ::* * : *: :* :.. . ::::*: : . . : * :* .* *: . * * : .: : ** **:.::.: : ::*:: .::: . :. . . . .: . : : :. : : * :: .* :. : :::: : : . : * . . : : : : : **: * * :: .: ", "identical_positions": 189, "similar_positions": 475, "identity": "5.34%" }, { "cls_id": "homologset.agr.MGI:2443930", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96JN0-1", "uniprot_id": "LCOR_HUMAN", "id": "Q96JN0-1", "name": "Ligand-dependent corepressor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQRMIQQFAAEYTSKNSSTQD----------------PSQPNSTKNQSLPKASPVTTSPTAATTQNPVLSKLLMADQDSPLDLTVR-------------------------KSQSEPSEQDGVLDLSTKKSPCAGSTSLSHSPG--------------------------------CSSTQGNGRPGRPSQYR------------PDGLRSGDGVPPRSLQDGTREGFGHSTS-----LKVPLARSLQISEELLSR------------------NQLSTAAS-----------LGPSGLQNHGQHLILSREASWAKPHYEFN----------------------------------------LSRMKFRGNGALSNIS--------DLPFLAEN----SAFPKMALQAKQDGKKDVSHSSPVDLKIPQVRG-------------------MDLSWESRTGDQYSYSSLVMGSQTESALSKKLRAILPKQS---RKSMLDAGPDSWGSDAEQSTSGQPYPTSDQEGDPGSKQ-----------PRKKRGRYRQYNSEILEEAISVVMSGKMSVSKAQSIYGIPHSTLEYKVKER--LGTLKNPPKKKMKLMRSEGPDVSVKIELDPQGEAAQS--ANESKNE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZPI3-1", "uniprot_id": "LCOR_MOUSE", "id": "Q6ZPI3-1", "name": "Ligand-dependent corepressor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQRMIQQFAAEYTSKTSSTQD----------------PSQPNSTKNQSLPKASPVTTSPTAATTQNPVLSKLLMADQDSPLDLTVR-------------------------KSQSEPSEQDGVLDLSTKKSPCASSTSLSHSPG--------------------------------CSSTQGNGRPGRPSQYR------------PDGLRSGDGVPPRSLQDGTREGFGHSTS-----LKVPLARSLQISEELLSR------------------NQLSTAAS-----------LGPSGLQNHGQHLILSREASWAKPHYEFS----------------------------------------LSRMKFRGNGALSNIS--------DLPFLAEN----SAFPKMAHQTKQDGKRDMSHSSPVDLKIPQVRG-------------------MDLSWESRTGDQYSYSSLVMGSQTESALSKKLRAILPKQN---RKSMLDAGPDSWGSDAEQSTSGQPYPTSDQEGDPGSKQ-----------PRKKRGRYRQYNSEILEEAISVVMSGKMSVSKAQSIYGIPHSTLEYKVKER--LGTLKNPPKKKMKLMRSEGPDVSVKIELDPQGEAAQS--ANESKTE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0B4KHV1-1", "uniprot_id": "A0A0B4KHV1_DROME", "id": "A0A0B4KHV1-1", "name": "", "aln": "MHISSYEISLERVAEECMGRRQWKHYQDKLTCSHLNIEEQQPIAIAGSEDEPSQYNHSSKEISQSNPNHCKTENHRLEQQHNGSQLLEEEDSENNQTSHDSSRTPTPGATSTPSPPPEPIDWRPSAKCNFCVNGRLLTVNAQGKLVAESAATATSSSTSNSHIHQHDSDSNSSASLPHHISSSSSSNNNSSGNRARHIAAASARATPAAATPANSLELYKLLTQRAAKMTSMDSMAAQLAQFSLLADFNLINSLASQQQQQQQQQIASAVTPTTSEVSAAAISPALKDTPSPSVDAPLDLSSKPSPNSSISGDVKSVRACATPTPSGRRAYSEEDLSRALQDVVANKLDARKSASQHHEQRSILDNRLFKMKHHDQEQDHDGDELEDSNDDAEAEVDSNASTPVYPAEFARAQLRKLSHLSEHNGSDLGEDVDRGSPKMGRHPACGNASANQGAPPSIPLDANVLLHTLMLAAGIGAMPKLDETQTVGDFIKGLLVANSGGIMNEGLLNLLSASQENSNGNASLLLQQQQHQQHHQQHHQQQQQQQHVAAYRHRLPKSETPETNSSLDPNDASEDPILKIPSFKVSGPASSSSLSPGGLVGGHHHPLNNNNSLSISNNSNHSSNSHRNGSNRSPHSASPMLAAAVAQGGYSAGNSLLTSSSSSIQKMMASNIQRQINEQSGQESLRNGNVSDCSSNNGGSSSLGYKKPSISVAKIIGGTDTSRFGASPNLLSQQHHSAHHLTHQQQQQQLSAQEALGKGTRPKRGKYRNYDRDSLVEAVKAVQRGEMSVHRAGSYYGVPHSTLEYKVKERHLMRPRKREPKPQPDLVGLTGPANKLQLDKLKAGPHGGSKLSNALKNQNNQAAAAAAAAAAAAAAATPNGLKLPLFEAGPQALSFQPNMFWPQTNATNAYGLDFNRITEAMRNPQASNHHGLMKSAQDMVENVYDGIIRKTLQASEGNGSAAGNGSNGSNGNGHGHGHGHGHALLDQLLVKKTPLPFTNHRNNDYAATCSSASGESVKRSGSPMGNYADIKRERLSADSGGSSDEEHSASHINNNNSDLAHNKNKSGGGGGGGGNGQTNGNGRSSRMTSRDDSETDASSLKSGESGGQQNHKMMDLNGGSSSSSHIKCESEAATGHHSPGHHTTSILHEKLAQIKAEQVDQADQLXEQPMAANPAFAWPPLAAHYYSF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: * **: ** * : : .** :. ::*.:..* . *** .:*:: .*.*.. .. *:****: : :: ** . . .: *: ::* . *:* *. .. .. . * *::: :* *:.* * : * : . *:::: .:** .: : :*: : * .* * *..* :.:*: :* :: . : * :. :. :*. * .: *.:* . *: :* * .: : :::::*.. .**:. * . .:* * . : : .:* . .** *. ::.: .: : * :. : : .*.*: .*. . .* : ::.: . .:* .* ***:**:*: : * **:..* *:*** :* * **:************ : . *. ** : .*: ** .:::: * . * :* *.: ", "identical_positions": 111, "similar_positions": 169, "identity": "9.34%" }, { "cls_id": "homologset.agr.MGI:2443935", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BP86-1", "uniprot_id": "SNPC4_MOUSE", "id": "Q8BP86-1", "name": "snRNA-activating protein complex subunit 4", "aln": "---------------------------------MDIDAEREKITQEIQELERILYPGSTSVHFEVSESSLSSDSE-----ADSLPDEDLETAGAPILEEEGSSE-------------------SSNDEEDPKDKALPEDPETCLQLNMVYQEVIREKLAEVSQLLAQNQEQQEEILFDLSGTKCPKVKDGRSLPSYMYIGHFLKPYFKDKVTGVGPPANEETREKATQGIKAFEQLLVTKWKHWEKALLRKSVVSDRLQRLLQPKLLKLEYLHEKQSRVSSELERQALEKQIKEAEKEIQDINQLPEEALLGNRLDSHDWEKISNINFEGARSAEEIRKFWQSSEHPSISKQEWSTEEVERLKAIAATHGHLEWHLVAEELG--TSRSAFQCLQKFQQYN-KTLKR--KEWTEEEDHMLTQLVQEMRVGNHIPYRKIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWAPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKKGRWNAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKILARKKQHLQRKRGQRPRHSSQWSSSGSSSSSS------EDYGSSSGSDGSSGSENSDVELEASLEKSRALTPQQYRVPDIDLWVPTRLITSQSQREGTGCYPQHPAVSCCT---QDASQNHHKEGSTTVSAA--EKNQLQVPYETHSTVPRGDRFLHFSDTHSASLKDPACKS-----------------------HTLMKERPKQPLLPSSRSGSDPGNNTAGPHLRQLWHGTYQNKQRRKRQALHRRLLKHRLLLAVIPWVGDINLACTQAPRRPATVQTKADSIRMQLECARLASTPVFTLLIQLLQIDTAGCMEVVRERKSQPPALLQPGTRNTQPHLLQASSNAKNNTGCLPS-MTGEQTAKRASHKGRPRLGSCRTEATPFQVPVAAPRGLRPKPKTVSELLREKRLRESHAKKATQALG-LNSQLLVSSPVILQPPLLPVPHGSPVVGPATSSVELSVPVAPVMVSSSPSGSWPVGGISATDKQP-----------------------PNLQTISLNPPHKGTQVAAPAAFRSLALAPGQVPTGGHLSTLG--QTSTTSQKQSLPKVLPILRAAPSLTQLSVQ---------PPVSGQ-------PLATKSSLPVNWVLTTQKLLSVQ----------------VPAVVGLPQSVMTPETIGLQAKQLPSPAKTPAFLE----------QPPASTDTEPK------------------------------------------------------------------------------------GPQGQEIP----------------------------PTPGPEKA-----------------------------------------------ALDLSLLSQESEAAIVTWLKGCQGAFVPPLGSRMPYHPPSLCSLRALSSLLLQKQDLEQKASSLAASQAAGAQPDPKAGALQASLELVQRQFRDNPAYLLLKTRFLAIFSLPAFLATLPPNSIPTTLSPDVAVVSESDSEDLG-DLELKDRARQLDCMACRVQASPAAPDPVQSHLVSPGQRAPSPGEVSAPSPLDASDGLDDLNVLRTRRARHSRR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LYZ6-1", "uniprot_id": "F1LYZ6_RAT", "id": "F1LYZ6-1", "name": "snRNA-activating protein complex subunit 4", "aln": "---------------------------------MDIDAEREKVTQEIQELERILYPGSSSVHFEVSESSLSSDSE-----ADPLPDEDLETAGAPVLEEERSSE-------------------GSNDDEDPKDKALPEDPETCLQLNMVYQEVIREKLAEVSQLLAQNQEQQEEILFDLAGTKCPKVKDAKSLPSYMYIGHFLKPYFKDKVTGVGPPANEETREKAAQGIKAFEQLLVTKWKHWEKDLLRKSVVSDRLQRLLQPKLLKLEYLQEKQSRVSSELEKQALEKQIKEAEKEIQDINQLPEEALLGNRLDSHDWEKISNVNFEGARSAEEIRKFWQSSEHPSINKKEWSTEEVERLKTIAASHGHLEWHLVAEELG--TSRSAFQCLQKFQQYN-KALKR--KEWTEEEDHMLTQLVQEMRVGNHIPYRRIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWAPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKKGRWDAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKILARKKQHLQKRRGQRSRHSSQWSSCSSSSSSSSSSSGSEDYGGGS-SSSSNSSEDSEVELEEPLQNSRALAPQQYSVPDIDLWVPTRLIDSRSQREETGCYPVHPAVSCR-------TQNHHKEGSTVVSAP--ERNQMQECCETHSTVPRGVQSLHSSDTHGASVKEPACKS-----------------------HTLVKERRRQPPLPNSRSGSDPGNSMAGPHLRRLWHGTFQNKQRRKRQALHRRLLKHRLLLAVIPWVGDINLACTQAVQRPAAVQTQADSIRMQLECARLASTPVFTLFIQLLQIDTAGCMEVVQERKTQPPALLQPGTRNTQPHLLQASSNAKNNTGCLLPGMLDEQTAKRTSQKGRPRLGSCKAEATPFQVPVAAPRGLRPKPKTVSELLREKRLRESHAKKATQALTALSSQLLVSSPVLLQPPLLPAARGSPVVGPAASSVELSVPVAPVMVSSSPSGSWQVGGISATDKQP-----------------------PNLQTIPLNPSHKGTQIAAPAAFRSLALASGHVSTGCPLNTLG--QTSTTSQKQSLPKVLPILPAAPSLTQLSVQPLSLPPVLNPPASGQ-------PPATKSSLPVSWVLTTQKLLSVQ----------------VPAVVGLPQPVTTPETIGLQAKQLPSPSKTPAFLG----------QPPASTDTEPK------------------------------------------------------------------------------------GPQGQQTP----------------------------PTPGPEKK-----------------------------------------------ALDLSLLSQESEAAILTWLTGSQGACVPPLGSRMSYHPPSLCSLRALSSLLLHKKDLEQKASSLVAGQAAGAQPEPKAGALQASLELVQRQFQNNPAYLLLKTRFLAIFSLPAFLATLPPNSVPTTLSPAMAVGSESDSEDFG-DLEPRDGATQLDCMACRVRANLMAPDPVVSHLPSWERRAPSPSAVSAPSHLDASDDLDDLDVLRTRHARHSRK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SXM2-1", "uniprot_id": "SNPC4_HUMAN", "id": "Q5SXM2-1", "name": "snRNA-activating protein complex subunit 4", "aln": "---------------------------------MDVDAEREKITQEIKELERILDPGSSGSHVEISESSLESDSE-----ADSLPSEDLDPADPPISEEERWGE-------------------ASNDEDDPKDKTLPEDPETCLQLNMVYQEVIQEKLAEANLLLAQNREQQEELMRDLAGSKGTKVKDGKSLPPSTYMGHFMKPYFKDKVTGVGPPANEDTREKAAQGIKAFEELLVTKWKNWEKALLRKSVVSDRLQRLLQPKLLKLEYLHQKQSKVSSELERQALEKQGREAEKEIQDINQLPEEALLGNRLDSHDWEKISNINFEGSRSAEEIRKFWQNSEHPSINKQEWSREEEERLQAIAAAHGHLEWQKIAEELG--TSRSAFQCLQKFQQHN-KALKR--KEWTEEEDRMLTQLVQEMRVGSHIPYRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGVGHWAKIASELPHRSGSQCLSKWKIMMGKKQGLRRRR-RRARHSVRWSSTSSSGSSS-------GSSGGSSSSSSSSSEEDEPEQAQAGEGDRALLSPQYMVPDMDLWVPARQSTSQPWRGGAGAWLGGPAASLSPPKGSSASQGGSKEASTTAAAPGEETSPVQVPARAHGPVPRSAQASHSADTRPAGAEKQALEGGRRLLTVPVETVLRVLRANTAARSCTQKEQLRQPPLPTSSPGVSSGDSVARSHVQWLRHRATQSGQRRWRHALHRRLLNRRLLLAVTPWVGDVVVPCTQASQRPAVVQTQADGLREQLQQARLASTPVFTLFTQLFHIDTAGCLEVVRERKALPPRLPQAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRVERTLPQASLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTSAKDKRL-----------------------STMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLS-----LTHIGGP-------HVATSVPLPVTWVLTAQGLLPVP----------------VPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRLPAFGGVIPAT------EPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPLPQPGPEKG-----------------------------------------------ALDLGLLSQEGEAATQQWLGGQRGVRVPLLGSRLPYQPPALCSLRALSGLLLHKKALEHKATSLVVGGEA----ERPAGALQASLGLVRGQLQDNPAYLLLRARFLAAFTLPALLATLAPQGVRTTLSVPSRVGSESEDEDLLSELELADRDGQPGCTTA----------------TCPIQGAPDSGKCSASSCLDTSNDPDDLDVLRTRHARHTRKRRRLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ASS0-1", "uniprot_id": "A0A8M3ASS0_DANRE", "id": "A0A8M3ASS0-1", "name": "", "aln": "MTHLSRDSWLYTHDVQVTYNSFIKVSPCPKMASDDLRAQRDKIQREILALESTLGADSSIADQLSSDNSSDYESDDSGPTVKRVERDDLETERLRIQREIEELENALGADAALENVLQDSDHDTDSSEDSADDLELPQNVETCLQMNLVYQEVLKEKLAELEQLLIENQQQQKEIEVQLSGPGNSIFSVPGVPPQKQFLGYFLKPYFKDKLTGLGPPANEETKERMKHGSIPVDNLKIKRWEGWQKTLLTNAVARDTMKRMLQPKLSKMEYLSNKLCRAEGE-EKEQLKAQIELIEKQIAEIRTLKDDQLLGDLQDDHDWDKISNIDFEGLRQADDLKRFWQNFLHPSINKSVWKQDEIYKLQAVAEEFKMCHWDKIAEALG--TNRTAFMCFQTYQRYISKTFRR--THWTEEEDDLLRELVEKMRIGNFIPYIQMSHFMVGRDGSQLAYRWTSVLDPSLKKGPWSKEEDQLLRNAVAKYGTREWGRIRTEVPGRTDSACRDRYLDCLRETVKKGTWSYAEMELLKEKVAKYGVGKWAKIASEIPNRVDAQCLHKWKLMTRSKKPLKRPLSSITTSYPRNKRQKLLKTVK----EEMFFNSSSDDESQINYMNSDESDDLAEDENLEIPQKEYVQTEMKEWIPRNAMVWTITPGSFRTLWVRLPTNEEE-----------LRESTKESGLGSDSSENSACPNDEPIMERNTILDRFGDVERTYVGMNTVVLHR-------------------------RTDDEKAMFKVCMSDVKQFIQMKATEFAVKKKKKIKNKKRTLRDVFS---LNTDLQKAVIPWIGNVIISIPAN----EAIFCEGDVVGIKAASIRLQKTSVFTFFIKAFHVDVNGCRTVIEIHKKLDIKMPLAINGNPKPTPISTSP--KTVAVLLQQSKAASEHKKPAEPSQQPSLPPSQKPSLPPSVPPSQQPTLPPPSQLSQPPPQPPSLPPSQPPAQQPSLPPPQPPSLPPPLPPPQPPSLPTSQQQSLPPSQQPSLPPSQQHSLPPFQNPSLPPSQQPSLPPSKQPPQPLPVRQITTPTLIYPNNLVITNPNMEGEVQHLVFKGLLLPQQPSKAVSHIPLPVMQPKTPAQPIVVSKSPSVQDSNSVKSSKRICKPTKKAQALMEQSKVKSRKKEPQKQNQGNKNVVFPTVTLQTSPVIKILSPARLVQVTGLSPNFSSNQTINMPDKSLTIKSPQPCSSGNLHQSAPVVVHSSTNPTFVHSSVSNVSRDNLNVSSTINISPRVSRDALNPTSFLNSTTFPLPQNLSVQQSVQIVPQIPINVVHKATCTKAAKTSSDSSSDESVVKQHQSSPSTGRSIPPAVFNIQPNPSTPPTLSSGPVIFNPNNKVVAPKLCGLNVSSSQLPTVSTQKTKYRPIRPLGPLPVVAPPSRKVTSMSRIRAQSEGEPLISLRELPAAGVNFDSHLIFPEKSSEVDDWMDGKGGIPLPHLDTSLPYLPPSAATIKTMTDLLRAKQPLLLAAKKVLP--AQYQDECNEEVEVEAIRKVVAERFASNPAYLLCKARFLSCFTLPALLATINPCEERQLLSEDDEEDDHLATINPSEERQSSTEDDEEDLQTN-----------------ERSQPPTARTELNMNENEASAKQFSGIGPKRQRNQRIKRLIK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHX0-1", "uniprot_id": "Q9VHX0_DROME", "id": "Q9VHX0-1", "name": "", "aln": "-----------------------------MDDADDLRINQQQLMDEISALLQNTAKPSAANALQLN-------------------------------------------------------------------QELQRRLMQVRTKILAMLQVVRARFSRNEDILVRRLRPRSHFGPNSLNLSGAILRKGTFR--------FKGNLFFRDIDGRSCPNNEDYEARCHTEMFPTDFDMHS--RHVWTLLDKKNVIMGIKQQLLEHRAHSTNALP------SGSLKRKPIER----------HLSTLVSLLATADSSFSIDWNQISTLDLEYRHSPYSCEAMWRVYLTPDLRRDDWSPEEDETLLAVATANRMQNWELIAASLDRRSDYQCFVRFHTALRFLLEPKNS--HRWSEEDNDKLRAIVDRNTANSVINWKKVVEYFPDKSKSTLIGRYYYVLHPSISHEPFTTKEDMMLFAAVEEYNGKFHCFPRSLFPNRSLTQLRTRYHNVLAQRNKTDSWSVQDDTRLMSFVTQYGASQWLNCATFLGNHTRTSCRTRFLVIKKFLE--------------------------------------------QNPNAKVEDLPRRRSKKVSLVNSDNWAQRLQEWQEDPESLVNDNP----------------------------PKGTRVRGPKSKKARIERQAESFSRLSKVDIEFCN----------------------------------------------------------------------------------------------------FFKFSYNLTLSTPKTFPVPKDVYNLAYVIRALAYKPPIRPSLLQNIFMPN---------DVLKCYNSMIRNLPDEEGDMKSPLLPPNWSTMMGFRALCILSGDCRKDTETRSFEYNESLPPIQLFRKRLQALFYRTTLLSRLESQLFTDLPSALVSLPRPKHDYAKMG----------------THVELIDPEPAPQNDLKSEPLSENEVINTVKQELEMEYTVP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22035-1", "uniprot_id": "BAS1_YEAST", "id": "P22035-1", "name": "Myb-like DNA-binding protein BAS1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSNISTKDIRKSKPKRGSGFDLLEVTESLG------------------YQTHRKNGRNSWSKDDD---------------------------------NMLRSLVNESAKELGYEN---------------------------GLEDVKTIQQSNHLSKCIAWDVLATRFKHTVRTSKDVRKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHG-PHWLSISMDIP---GRTEDQCAKRYIEVLGPGSKGRLREWTLEEDLNLISKVKAYGT----KWRKISSEMEFRPSLTCRNRWRKIITMVVR-GQASEVITKAIKENKNIDMTDGKLRQHPIADSDIRSDSTPNKEEQLQLSQQNNPSLIKQDILNVKENESSKLPRLKDNDGPILNDSKPQALPPLKEISAPPPIRMTQVG---------------------------------QTHTSGSIRSKVSLPIEGLSQMNKQSPGGISDSPQTSLPPAFN-----------------------------------PASLDEHMMNSNSISDSPKHAYSTVKTREPNSSS-----------------------------------------------------------------------------------------------------TQWKFTLKDGQGLS-------ISNGTIDSTKLVKELVDQAKKYSLKISIHQHIHNHYVTSTDHPVSSNTGLSNIGNINGNPLLMDSFPHMGRQLGNGLPGLNSNSDTFNPEYRTSLDNMDSDFLSRTPNYNAFSLEATSHNPADNANELGSQSNRETNSPSVFYPQAN-----------TLIPTNSTATNNEIIQGNVSANSMSPNFNGTNGKAPSSTASYTTSGSEMPPDVG---------------------------------PNRIAHFNYLPPTIRPHLGSSDATRGADLNKLLNPSPNSVRSNGSKTKKKEKRKSE-----------------------------------------------------------------------SSQHHSSSSVTTNKFNHIDQSEISRTTSR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDTPLRDEDGLDFWETLRSLATTNPNPPVEKSAENDGAKPQVVHQGIGSHTE------------DSSLGSHSGGYDFFNELLDKKADTLHNEAKKTSEHDMTSGGSTDNGSVLPLNPS----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. . .. . : : . * . ::: . : ::: . : : . *: ::. . : . . . * *.: : *. :* * .* :: : . : . . .*: *:: * *. : :: : : *: : : : : : . : . * :.. : . . : : : ... : . . . . . .: . . . : : : . : : .: : . . . . ... . . . ", "identical_positions": 14, "similar_positions": 106, "identity": "0.84%" }, { "cls_id": "homologset.agr.MGI:2443938", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9PJH5-1", "uniprot_id": "A0A8M9PJH5_DANRE", "id": "A0A8M9PJH5-1", "name": "", "aln": "----------------------------------------------------MTTA-----LTVTSAALLCVVCARPALMPDQYARGVDW--LIRYGYLQSPDTLIGGLQTKESIEEAVRKMQRFAGIEETGNLDQKTLEMMGRPRCSLPDTISFEELLKRNRRGKNKVMMKKKRYTLPKMRWDKTDITWS-------MQDFPPPSVSPALNPGLVRLILGNALRVWSENTPLRFHYSPDEPSPQTDITVTFTSGYHEDGYPFDGKGGALAHAFFPGKGDLAGDTHFDAEESWTYG--DWSSD-SDLFTVAVHEFGHALGLFHSSSSDSIMKPYYFSPVGEMNSYSLTAVDRLGIQALYG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQHNLKPPPSVAAPTTYPTQFSTTYLLHPPYYPPDSADRCQGGYDAVANIRAEIFFFRGQHFWRVDHSGSLLSSTPALIHSFWIGLPPDTARVDAAYERR-DGHIVFFIGNQYWVFRNTMALPGYPRQLSDWGLHTAAGQLAESVEAVFVWPHNGKTYVFSSGLYWRFDEAG--GERKMEEGYPKPAAIWG-MPSHPDDIIAFLDGETYFFKDSNYWILQRGGLDLESASPKSIATDWMKCDRHVSAP----TPEIPRDR---NCSCVQNVAAVMRSLSVIIYLTNIICILVVTVF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7F1N5-1", "uniprot_id": "E7F1N5_DANRE", "id": "E7F1N5-1", "name": "", "aln": "----------------------------------------------------MSFSGYLGLVYLTCPMLVFFSAVHSAPVKDQYSRGVDW--LSRYGYLPPLDPRTGQLQSKDGIERAIREMQRFAGLKETGKLDSDTLTLMNTPRCSLPDIIGIEDKLKKRRR---------KRYATTGLRWTKSDITWS-------VQNYP--SVHKRLTPTQVDPIISYALKAWSDVTNLNFYGASSSEKDRADIRISFARSLHDDGYPFDGKGGTLAHAFFPGESDVAGDTHFDDDEIWTYL--DESG--TDLFAVAVHEFGHALGLSHSSSSPSIMKPYYQGSVGDVGSYILPDDDREAIQSLYG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKISS-PTPSPNKPTSHLPKPPATYPKGPVKPDPSIQNRCEGGFDAVANLRGEVFFFKGPYFWRIQRTGSLVSFQPAHIKNFWMGLPPTTNKVDAVYERKVDNAIIFFIGSQYWVFKNTEVLPGYPRPLSDWGMITQDGRKVMRVDAAFIWAHNGKTYIFSGGEFWRFSEGRETELRGPDTGYPRNTNLWKGAPSNPDDVITWGQGDAYFFKDNSYWVLKNGEMDQTSVTKKSTAVDWMMCQQETTK-----APESPRRREGVNCYCDNSAGLQMSVSAWLLLITALLHIGFNSQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6ABC2-1", "uniprot_id": "A0A8I6ABC2_RAT", "id": "A0A8I6ABC2-1", "name": "Matrix metalloproteinase-25", "aln": "MCLPGSQISPAHLYYLVSAPCR-AGSLTSSIPPGRRESGLFRMPLRSVQAERILRLQALGLPLLVLLLVLLQPVRAQNLRAQDVSMGVDW--LTRYGYLPPADPVHAQMQSLGKLQDAIKVMQRFAGLPETGQMDPITIATMHKPRCSLPDILGPAGLVRRRRR-----------YTLSGSVWKKRTLTWRISFSLLSIQSFS---QSSRLSQSVVRTLVSYALDVWAVASGLTFQEVDS-QYQEPDIVIHFSRAYHQDSYPFDGPGGTLAHAFFPGEHPISGDTHFDDEETWTFG--STDGEGTDLFAVAVHEFGHALGLGHSSAPDSIMRPFYQGPVGDPGTYRLSQDDRDGLQQLYG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVSQTPNDKPTRKPLVPPPQPPVMPPDSPSTPVP---DRCKGNFDAVANIRGEIFFFKGPWFWRLQPSGQLVSPRPAGLHRFWEGLPNDVRVIQAAYARPQDGRIILFSGPQFWVFQ-ERQLQGAARPLVEFGLPPG-----EEVDAVFSWPFNGKTYLIRGQKYWRYDEVAG----SPDPDYPRPLSLWEGAPFAPDDVTISNTGDTYFFKGTHSWRFAKGSVKSESDSPQPIGPTWLDCPAPNSDPQVPSPPKTTPETRSCDCHCELNQTSEQLSSTFLLPLLPLLAGAIFSC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U435-1", "uniprot_id": "MMP25_MOUSE", "id": "Q3U435-1", "name": "Matrix metalloproteinase-25", "aln": "MCFPGSQISPARLYYLVSAPWICTGSLTSSRLPRRRESGPLRVPPRSVQAERILRLPAFGLPLLALLLVPLLPVRAQNPDAKVVSMGVEW--LTRYGYLPPADPVHAQMQSLEKLQDAIKVMQRFAGLPETGQMDPMTIKTMRKPRCSLPDVLGAAGLVRRRRR-----------YSLSGSVWKKRTLTW-------SIRSFS---QKSQLSPQIVRTLLSYALAVWATESGLTFQEVNS-QYQEPDIIIHFARAYHQDSYPFDGSGGTLAHAFFPGEHPISGDTHFDDEETWTFG--STDDNGIDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPATYRLPQDDRDGLQQLYG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVSQNPNARPTRKPLVPPPQPPAMPPDSPATPVP---DRCEGNFDAVANIRGEIFLFKGPWFWRLQPSGQLVSPRPAGLHRFWEGLPTHVKVIQAAYARPLDGRIILFSGPQFWVFQ-ERQLEGAARPLVEFGLPPG-----EDVDAVFSWPHNGKTYLIRGQKYWRYDEVAA----RPDPGYPRALSLWDGAPFAPDDVTISNTGDTYFFKGTHFWRFAEGSVKAESDSPQPIGPKWLDCPAPNSDPRVTSPPKTTSKTRSCDCHCELNQASEQLS-PLLLPLLPLVAGEVFSY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPA2-1", "uniprot_id": "MMP25_HUMAN", "id": "Q9NPA2-1", "name": "Matrix metalloproteinase-25", "aln": "-----------------------------------------------------MRLRLRLLALLLLLLAP--PARAPKPSAQDVSLGVDW--LTRYGYLPPPHPAQAQLQSPEKLRDAIKVMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLGVAGLVRRRRR-----------YALSGSVWKKRTLTWR-------VRSFP---QSSQLSQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFG--SKDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KAPQTPYDKPTRKPLAPPPQPPASPTHSPSFPIP---DRCEGNFDAIANIRGETFFFKGPWFWRLQPSGQLVSPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQ-DRQLEGGARPLTELGLPPG-----EEVDAVFSWPQNGKTYLVRGRQYWRYDEAAA----RPDPGYPRDLSLWEGAPPSPDDVTVSNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDCPAPSSGPRAPRPPKATPVSETCDCQCELNQAAGRWPAPIPLLLLPLLVGGVASR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MPP3-1", "uniprot_id": "D2MP_DROME", "id": "Q8MPP3-1", "name": "Matrix metalloproteinase-2", "aln": "---------------------------------------MFSKYVLATLLALFAQSMCIQELSLPPEGSHSTAATRSKKAKTAISEDIMYNYLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWS-------------MVNRSMPDASKVERMVQTALDVWANHSKLTFREVYS---DQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEG-RGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQ---NNEVAGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGTSG-LYNGYPTEIRRHWSALPENLTKVDAVYENK-QRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPPT----LTHIDASFVWGHNNRTYMTSGTLYWRIDDYTG----QVELDYPRDMSIWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHARAKLSARRWMQCARSANEVD--DEQRWTASLVSEGEETGRSGSRELRINHFILSILLLAIANWRS--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: : * ::.** . . ::: :. *:: :* *..: **.:* * : ***.: * . . :: * : :** * :: ** .*. : * * . ..** : *: * *.* *** * .*****:**: .**:*** :* *.: . .. ::: **:**:**:*** **: . ::* *:* .: *. ** .:* *** : . * : * :**:: :*.* *:*:* :**: :* * . *: :: .* .** ::*.* . : *::* * :::**. * .: * . *: . ::* * * *.:**: . :** .: : .**: :* * *.:****. * : . :. : . *: * . . . . . : : : : ", "identical_positions": 115, "similar_positions": 137, "identity": "13.84%" }, { "cls_id": "homologset.agr.MGI:2443939", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q561R1-1", "uniprot_id": "CENPT_RAT", "id": "Q561R1-1", "name": "Centromere protein T", "aln": "MADLSSPDGDPTIRTLLRHVLDTADSHTPRRRQSTQTNPQRRRSQTPYSKRQGSQRKTSTRKHSHGTGSVG--------RLARVQGHG--------HLEEQTPRTLLQNILLTAPESSTVMP--NPVVKPAQVPEVARPSRRGSSRGSLELQLPELDPPSTLAPGLKAPGKRKQK---LRLSVFQQEVNQQLP--------------------LPQEQR--GAADGSSLASSFNLSFVPSVQPQTVDRPGLARRRPVRRPVNIGAFLQNLE-------------------------------------------------------------------------------------------------NKSLTSALPGDSHRTPVAALPTDVVFEDTQPFSQPLAGCSLSVHHSLPN------------------------------------PSQTEVEDAERVVGPRTPSTGTRPQS----------------------------------------------------------------------------------------------------------------------QMSRAGFGASPLPFSEPQPQS--------PELREAVGSKEAEEPKDLEGSSGDEETSGMPASRELSSS--AQDLLLAEEPHQLFEPPPSPGVAAVSSE---SVPAKLPSRT--------------------------------------------------------------------------------------------RTAQPRHHQDPYKAGLSHYVKLFSFHTKMPVEKAALEMVEKCLDEYFQRLCNDLEVFAAHAGRKTVKPKDLELLMRRQGLVTDQVSLHVLVERYLPLEYRQQLIPCAFRGNSVFPAQ--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TJM4-1", "uniprot_id": "CENPT_MOUSE", "id": "Q3TJM4-1", "name": "Centromere protein T", "aln": "MADLSFSDGDPTVRTLLRRVLETADSRTPMRRRSTRINAQRRRSQTPYSNRQGSQTKTSARKQSHGARSVG--------RSTRVQGRG--------RLEEQTPRTLLRNILLTAPESSTVMP--DPVVKPAQVPEVARSSRRESSRGSLELHLPELEPPSTLAPGLTAPGKRKQK---LRLSVFQQEVDQGLP--------------------LSQEPRRSRSADVSSLASSFNLTFVLPGQPETVERPGLARRRPIRQLVNAGALLQDLE-------------------------------------------------------------------------------------------------DNSLASALPGDSHRTPVAALPMDVGLEDTQPFSQSLAAFSLSGKHSLPS------------------------------------PSRPGVEDVERVMGP--PSSGTRLQS----------------------------------------------------------------------------------------------------------------------RMSRSGPAASPSPFLEPQPPP--------AEPREAVGSNEAAEPKDQEGSSGYEETSARPASGELSSS--THDSLPAEQ------PPPSPGVAVLSSEPLESVTAKCPSRT--------------------------------------------------------------------------------------------QTAGPRRRQDPHKAGLSPYVKFFSFCTKMPVEKTALEIVEKCLDKYFQHLCNDLEVFASHAGRKIVKPEDLLLLMRRQGLVTDQVSQHVLVERYLPLEYRQQLIPCAFSGNSVFPAQ--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96BT3-1", "uniprot_id": "CENPT_HUMAN", "id": "Q96BT3-1", "name": "Centromere protein T", "aln": "MADHN-PDSDSTPRTLLRRVLDTADPRTPRRPRSARAGARRALLETASPRKLSGQTRTIARGRSHGARSVG--------RSAHIQASG--------HLEEQTPRTLLKNILLTAPESSILMP--ESVVKPVPAPQAVQPSRQESSCGSLELQLPELEPPTTLAPGLLAPGRRKQR---LRLSVFQQGVDQGLS--------------------LSQEPQ--GNADASSLTRSLNLTFATPLQPQSVQRPGLARRPPARRAVDVGAFLRDLR-------------------------------------------------------------------------------------------------DTSLA---------------PPNIVLEDTQPFSQPMVG-SPNVYHSLPC------------------------------------TPHTGAEDAEQAAGRKTQSSGPGLQKNSPGKPAQFLAGEAEEVNAFALGFLSTSSGVSGEDE---------------------------------------------------------------------VEPLHDGVEEAEKKMEEEGVSVSEMEATGAQGPSRVEEAEGHTEVTEAEGSQGTAEADGPGASSGDEDASGRAASPESASS--TPESLQARRHHQFLEPAPAPGAAVLSSEPAEPLLVRHPPRP--------------------------------------------------------------------------------------------RTTGPRPRQDPHKAGLSHYVKLFSFYAKMPMERKALEMVEKCLDKYFQHLCDDLEVFAAHAGRKTVKPEDLELLMRRQGLVTDQVSLHVLVERHLPLEYRQLLIPCAYSGNSVFPAQ--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YX66-1", "uniprot_id": "A0A8M6YX66_DANRE", "id": "A0A8M6YX66-1", "name": "", "aln": "---MDLTEEDLSARVLLRKVLHTEQPRSPVTRSANSVRRSARMKNAAGLESPGSALRHRLKKKLHESAAASPLPLPKRMRSSVVKQNPPNMAPSTLDDEDLTTRGLLRGIIHMETETSLLMSGQPALQESEPNPETSVSSAGERTEGLSGAELSDLTLHTEPLTHVVRGLSRKKQQHVFSVSALEKQFDQLTDNTEDVSRVSERGDVFQEKPDTSQDSDFSAGSKSLCSVSGLNLTLKTPFVERRSERAVLQRKVSNRRLQSVEAFDEAVQRCLEQGPNQEQSVSLAGKTLDDSSWQKFTLGLNDVTELYVQMKKDDTVEPSAEIDNDEQAETEKDEQYHVSEIPNDRDSKILIQDEKEHEMESLLLDDEEVVPSSQESPRDEVFLNTEYDIILAPTQAMTESLPQSQNAELEGQLSGENDVVVEEIAHEEIVEDVEHENVVEIEAEEVEYAEENSDGLNYPERITRRAHGSEGAGAVLAIPGTSTRVTKSFGAGLNPREKDLLDLIDGDRESVENILDEERQALVSPMSPQFHHEEVIITSEQRSTQNEASLNEDDLPQVTENEDVNQSEEKREELIDSEPANQPPEPAEELIESQSANQSTEADEEKELIDSEPTNQSTKPEDDEEEEELMDSESTNQSTKPDDDEDEEELMDSEPTNQSTKPDDDEEELIDSEPTNQSTEPPQDGEDMMESELANQSLQPAEDKEEMLESEPANLTSEAAVEEEDIIDSEPANQSYEFAQEEEEEEDVDEDDARSAELSIKTPAFVKQKRVFASPSAQTTLTVLKEVNAGAGPQVSRRAPRQKRQTGTDVLPKSYVMSIFKHFAKTKVASDVYPVINEILKKYFDRLADDLETYATHAKRKTIEVEDFELLMRRQGFVTDSMPVNVLIEKYLPLEYRKLLIPVATSGNKVIPTQRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: * : *.***:**.* :.::* : ::. . .. : : : * : :.. * : :: *: *.* **:.*: .*:* :*. .: :. *:. .* : * .*.:* : . : **:: : :*.::: .:* .*: :. . . .:**:: . . :*. * *: . *: . *: . :. : .:. :: : **.:::.: . .. : *: * *. .. . . .: * * .*: : :. ... *: .: : :.. : * . .* * :.** : ::. : : .. * :.:*.. :* : . :::: *.:**::*.:***.:*:** ** :: :*: *******:***.:. :**:*::******: *** * **.*:*:* ", "identical_positions": 95, "similar_positions": 173, "identity": "10.34%" }, { "cls_id": "homologset.agr.MGI:2443952", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9G5-1", "uniprot_id": "D4A9G5_RAT", "id": "D4A9G5-1", "name": "", "aln": "MMMYIRQRKETKPVEVSEDFPSP-------KEDVKLEKKLPSGCASG-----------RFWKILSSAVGGTVALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLLQGFHGLIYDNKTESMRTINLLQRMNIYQEVFLSVLYRVLP--IQKYLEPVYFYIYTLFGLQAVYVTALYITSWLLSGTWLSGLLAALWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNLQPLSERLTLLAIFVS---TFLFSLTWQFNQFMMLLQALVLFILDSLDMLPAVKATWLYGIQISCLLLVCMLQFFNSMILGSLLISFNLSVLIVRKLQKNLKTG--------TFLIRIWKLLLHLLLVFCLTLFLNNIIKKILNLKS-----------DEHIFKFLKAKFGFGATRDFDANLYLCEEAFGLLPLNTFQRLSETLLFYAYMFVLLVTVVTASVVAFHNLSDSTSLQPVDQTRKRVVDLKPEAAYNLIHTILFGVLALSTMRMKYLWTSHMCVFASFG----LCSSEIWELILRLVHLCNPKRIWVMRYSVPVLTLLCLCCKSWPGMMDELSELKEFYDPDTVELMNWINSNTPR------KAVFAGSMQLLAGVKLCTGRTLTNHPHYED--KSLRERTQAVYQIYAKR---SPE---------EVHALLRSFGTDFVIL----------------------EDSICYERRHHRG-----------CRLRDLLDVANGHEMDGPGESDPDLRP---------------------------ADHPRFCEEIKRNLPSYAAHFT------RVFQNKTFHVYKLSRNK------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q71B07-1", "uniprot_id": "D19L3_MOUSE", "id": "Q71B07-1", "name": "Protein C-mannosyl-transferase DPY19L3", "aln": "-MMYIRQRKETKPIEVSEDFPSP-------KEDVKLEKKLPSGCASG-----------RFWKILSSAVGGTVALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLLQGFHGLIYDNKTESMRTINLLQRMNIYQEVFLSVLYRVLP--IQKYLEPVYFYIYTLFGLQAVYVTALYITSWLLSGTWLSGLLAALWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNLQPLSERLTLLAIFVS---TFLFSLTWQFNQFMMLLQALVLFILDSLDMLPAMKATWLYGIQISCLLLVCTLQFFNSMILGSLLISFNLSVLIVRKLQKNLKTG--------SFLTRIWKLLLHLLLVFCLTLFLNNIIKKVLNLKS-----------DEHIFKFLKAKFGFGATRDFDANLYLCEEAFGLLPLNTFQRLSETLLFYAYMFVLVVTVVTASVVAFHNLSDSTSLKSMDQTRKRAVDLKPEAAYNLIHTILFGVLALSTMRMKYLWTSHMCVFASFG----LCSSEVWELLLRLVHLCNPKRIWVLRYLVPVLTLLYLCYKSWPGVMDELSELKEFYDPDTVELMTWINSNTPR------KAVFAGSMQLLAGVKLCTGRTLTNHPHYED--KSLRERTQAVYQIYAKR---SPE---------EVHALLRSFGTDFVIL----------------------EDSICYERRHHRG-----------CRLRDLLDVANGHEMDGPGESDPDLRP---------------------------ADHPRFCEEIKRNLPSYAAHFT------RVFQNKTFHVYKLSRNK------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZPD9-1", "uniprot_id": "D19L3_HUMAN", "id": "Q6ZPD9-1", "name": "Protein C-mannosyl-transferase DPY19L3", "aln": "-MMSIRQRREIRATEVSEDFPAQ-------EENVKLENKLPSGCTSR-----------RLWKILSLTIGGTIALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLVQGFHGLIYDNKTESMKTINLLQRMNIYQEVFLSILYRVLP--IQKYLEPVYFYIYTLFGLQAIYVTALYITSWLLSGTWLSGLLAAFWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNLQPLSERLTLLAIFIS---TFLFSLTWQFNQFMMLMQALVLFTLDSLDMLPAVKATWLYGIQITSLLLVCILQFFNSMILGSLLISFNLSVFIARKLQKNLKTG--------SFLNRLGKLLLHLFMVLCLTLFLNNIIKKILNLKS-----------DEHIFKFLKAKFGLGATRDFDANLYLCEEAFGLLPFNTFGRLSDTLLFYAYIFVLSITVIVAFVVAFHNLSDSTNQQSVGKMEKGTVDLKPETAYNLIHTILFGFLALSTMRMKYLWTSHMCVFASFG----LCSPEIWELLLKSVHLYNPKRICIMRYSVPILILLYLCYKFWPGMMDELSELREFYDPDTVELMNWINSNTPR------KAVFAGSMQLLAGVKLCTGRTLTNHPHYED--SSLRERTRAVYQIYAKR---APE---------EVHALLRSFGTDYVIL----------------------EDSICYERRHRRG-----------CRLRDLLDIANGHMMDGPGENDPDLKP---------------------------ADHPRFCEEIKRNLPPYVAYFT------RVFQNKTFHVYKLSRNK------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G0T2-1", "uniprot_id": "A0AC58G0T2_DANRE", "id": "A0AC58G0T2-1", "name": "", "aln": "-MRACRSRKSNSDDNSGSALHRPPLVNFGTKDNSRVYKSGQRGIEECLKLSWIHILGPNCWPAVVIAAGLLLAGVIGLFHAWCVYSIHENLLWFSHLKEVEREISFRTECGLYYSYYKQMLKAPTIQQGLYELTHDNTTESKRTINILQRMNIYQEVFLSILYRILP--IQTYLEPIYFYIYTVFALQTVYVIALFITSWLLSDSWLAGALSGVWYILNRVDTTRVEFTISLRENWSIPFFALQVAAITCYLRPKLKPIHQRVVLWLVFVS---TFCFCLTWQFNQFVLLVQALIIYTLDCLDFLTAEQVVSLYLMQVSSLLLVWLLQFCNSMILGSLVLSFIVSALFIKHFQTGLKMG--------GFVIRVGKLALHTLLVLALTFTINYSAKKVLQLKS-----------DEHIFKFIKAKFGFGATRDFDASLYLCEEAFGLLPLDTFERLAGTVLLYPYLCTLSVLFILLLLVALSNLSLNGLGQASGEKEDRTFKMRPDVAYNLMHTVFFGLLAFSTMRMKYLWTGHMCTIAAFG----VCGKEVWALYLRVLHCNTKTAMRLIRYSVPIVILAFLYYKFWPRLMEEISELREFYDPDTVELMEWISMETSPPTTGLLKCLCVATRIHRRALSYSTIGMKIEISKTKT--ETISALTDGVICYLNKKEGSTPEFEEGVSYILQKHTLSNKFGQMYLFVGPGSLKFKTTPHNFSEAAQTSAKEALCPPSPEMTGGEPDIFSRGGHISLRGQITEFHGVRMTRARVPIVDLKIKCLEGTFSVSLWREAALTELFVGDEVLITHLRPCVQETGTGKFHSSNYTTVEIAEGQMQETVVEVIGVSNVNHTCHFLGSDSQVYVVPQIVFAGNPDDLIARLPLHLSLKHVNRRVFQISEVSE--------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWR8-1", "uniprot_id": "DPY19_DROME", "id": "Q9VWR8-1", "name": "C-mannosyltransferase dpy-19 homolog", "aln": "-------------------MREP--------------------------------------NLYVILSHALIGCGFFFLYVQHVRVIFETRTNIQQLNQLEREALLRREDALYYAFYKQLAEGPDFWHGYEQLKNVTDIEYPHSVNVLQRFYVLPELVTAYFFHVVRSGFNPMVQPMQFYLEFVWLMGGVTLLVLYLYGTLLSENIFGGIYGVISYLMFHSFVAKIYERPLARENFAFPFIFLQMFYLCICIGRIIHRQRHTSRMFMIFAMSLFTACALLSWQFSTFIFTTQILIMMTSWNASALPTALVNAFVLDYSLSHLLGHALAFVMSHGNSQLLLTWQLSISLFLFLITMVRQLRHVRSRRLGHAQDLLNGDLFSLKFLMLTLLLASSVQTTLIELFNRAGVVSVTEGDQQHFFDICAHWALQVNVGFVAHLSACNPQYARVAWSELWQLVKTMIVKPYCMYGVVMLAMFFRRWRKSGAPVSALTEEQRERARKYVLEDFIEEHFVSMSDMSSKETEKQLYKCFRLLKSCDYDYERYKRAQASLRKEQPPARDDFMQDIKRLRAQINRNSVKQRKERAQETKEAATDGASTPTEEEDKDPEAESESKKKNQEPGSGETETESAADPTETPPSRSADNEEEEEEHSATAAGCGSNSSGHRQRKRSSSRRSSVVPTANAQILNMHYVYSFLQMLVFTLIGLAVRKLFFLSFTQG------CVIAPTVCSKLWYHRQR-----NIFWSVSLAVFLLSMFDPGMVNIREEYFPTRYSKSGDDLDSMLEWIKLNTERDAVFAGPVDIIGTVHLTTKRPIVNHAHLEM-----RQIAERTEHVYSVYSRQQSSDIYNQCAQLKIQYLIISLDECTNEVRDDCDLLAIWDDKQPAYQKYPQFCHELLHKNVPSFLKVFANDHYGIIKMFSQSVQINLKHNKMPEMSI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : :: : :.*. :.:::::*** :* * .***::***: :.* : :* * . * :::*:***: : *:. : ::::: :: ::*: **: :: : : : .*:: . *** . :.* . . *: : .::: ***:::**: :*: : : :: . : :* * *:***. *:: * *:: . *.: . : . ** * * * ..*:::: :* : : . :: . : : *. : .: **: : :. * *:: * : *::.: .. .* * * *: :. :. . : :* *::. .* : . . : . . :. ::: :. .. * : : * .. . : . . : .: : : * * * *. . : . . . . . . : . : :: * ::: . : : : ::* * : . * : . : : : . .* : : ", "identical_positions": 78, "similar_positions": 199, "identity": "8.25%" }, { "cls_id": "homologset.agr.MGI:2443955", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8Y2-1", "uniprot_id": "G3V8Y2_RAT", "id": "G3V8Y2-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MGAPGLRAAAAALGLLLCAGLGRAGPAGSGGH---------------------------------------------------------------------------------GAPGQLSDEATRRPCPAACHCLGDLLDCSRRRLIRLPDPLPAWVTRLDLSHNRLSFIQASSLSHLQSLQEVKLNNNELETIPNLGPVSANIRQLSLAGNAIDKILPEQLEAFQSLETLDLSNN--NISELRTAFPPLQLKYLYINSNRVTSMEPGYFDNLGSTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLRELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNALHVGNNKVSYIADCAFRGLSSLKTLDLRNNEISWTIEDMNG--AFSGLDKLRQLILQGNRIRSITKKAFAGLDTLEHLDLSGNAIMSLQNNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQPLKGRSIFTVSPDGFVCDDFPKPQITVQPETQSAIKGSDVSFTCSAASSSDS------PMTFAWKKDNE------ALQDAEMENYAHLRAQGGELMEYTTILRLRNVEFASEGRYQCVISNHFGSSYSVKARLTINMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGIDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSVSANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGS------PPPRLNWTKDDSPLVVT------ERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPHMTAPSLDGDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYISSENGSHHQFVTSSGGGFFLPQHDSAGTCHFDDSSEADVEAAPDPFLCPFVSSSGPVYLKGNLYGPDPFEVYLPGCSSDPRIALMDHCESSYTKK-DCFSCAHPSEEPCERSLKSIPWP-HSRKLMNSAFSQNEGPAVQTLRLNKS-VDFSTSPEPGSATSSNSFMGTFGKPLRRPQLDALSSFAQPPDCQPRPCHGKSLSPPELDSESEEDEKERTDFREENHRCTYQQILHSYRTPDRQPCDSDT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P1C6-1", "uniprot_id": "LRIG3_MOUSE", "id": "Q6P1C6-1", "name": "Leucine-rich repeats and immunoglobulin-like domains protein 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MGAPGLRAATAALGLLLCAGLGRAGPAGSGGH---------------------------------------------------------------------------------GAPGQLLDDDAQRPCPAACHCLGDLLDCSRRRLVRLPDPLPAWVTRLDLSHNRLSFIQTSSLSHLQSLQEVKLNNNELETIPNLGSISANIRQLSLAGNAIDKILPEQLEAFQSLETLDLSNN--NISELRTAFPPLQLKYLYINNNRVSSMEPGYFDNLASTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEVLQLDHNNLTEITKGWLYGLLMLRELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNALHIGNNKVSYIADCAFRGLTSLKTLDLRNNEISWTIEDMSG--AFSGLDRLRQLILQGNRIRSITKKAFAGLDTLEHLDLSGNAIMSLQSNAFSQMKKLQQLHLNTSSLLCDCQLRWLPQWVAENNFQSFVNASCAHPQLLKGRSIFTVSPDGFVCDDFPKPQITVQPETQSAIKGSDVSFTCSAASSSDS------PMTFAWKKDNE------ALQDAEMENYAHLRAQGGELMEYTTILRLRNVEFTSEGKYQCVISNHFGSSYSVKAKLTINMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSVSANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGS------PPPRLNWTKDDSPLVVT------ERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPHMTAPSLDGDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYISSESGSHHQFVTSSGGGFFLPQHDGAGTCHFDDSSEADVEAASDPFLCPFVGSTGPVYLQGNLYSPDPFEVYLPGCSSDPRTALMDHCESSYVKQ-DRFSCARPSEEPCERSLKSIPWP-HSRKLTDSTYPPNEGHTVQTLCLNKSSVDFSTGPEPGSATSSNSFMGTFGKPLRRPHLDAFSSSAQPPDCQPRPCHGKSLSSPELDSESEENDKERTDFREENHRCTYQQIFHTYRTPDCQPCDSDT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXM1-1", "uniprot_id": "LRIG3_HUMAN", "id": "Q6UXM1-1", "name": "Leucine-rich repeats and immunoglobulin-like domains protein 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MSAPSLRARAAGLGLLLCAVLGRAGRSDSGGR---------------------------------------------------------------------------------GELGQPSGVAAERPCPTTCRCLGDLLDCSRKRLARLPEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSN--NISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNG--AFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDS------PMTFAWKKDNE------LLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGS------PPPKLNWTKDDSPLVVT------ERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYVSSESGSHHQFVTSSGAGFFLPQHDSSGTCHIDNSSEADVEAATDLFLCPFLGSTGPMYLKGNVYGSDPFETYHTGCSPDPRTVLMDHYEPSYIKKKECYPCSHPSEESCERSFSNISWPSHVRKLLNTSYSHNEGPGMKNLCLNKSSLDFSANPEPASVASSNSFMGTFGKALRRPHLDAYSSFGQPSDCQPRAFYLKAHSSPDLDSGSEEDGKERTDFQEENHICTFKQTLENYRTPNFQSYDLDT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1ZAB1-1", "uniprot_id": "A1ZAB1_DROME", "id": "A1ZAB1-1", "name": "", "aln": "MHVSAIKGRHPTRESNDDSSMVISNYRICDIKTSGNGKYLMSWSRRRRRNNNNNNNSSSNNNNAASESRSNDNCNYSTTNDFNKINKLLLITYMLLITAATICQSAAQSPSSSNGNGVGGSGSTGGSPLSALLKSGGASYNQQLPQQQLFAMLTRNGGGSSGPRSSGGNRGYTSARQHFMALSEDYSDADVDEEDMAALHYPLSASHPPAGVQGSSSSSGISIQSGSLETNGFVADDGGQYEHAQKALEAAAAAAKASNKYNIDCPKDCKCLNVLFDCDKLHLERVP-VLPSYVQTLHLANNKLNDTTVLEIRNLLNLTKVSLKRNLLEVIPKFIGLSG-LKHLVLANNHITSISSESLAALPLLRTLDLSRNKLHTIELNSFPKSNNLVHLILSFNEITNVNEHSFATLN-NLTDLELSNNRLSTLPIRVFKNLNQLKKLALNFN-QLEINWSTFRGLESMKNLQLKSNKIRALQDGVFYVMHKIETIDLAMNQISSLSRQGLFNLTKLRHLNLSFNAISRIEVDTWEFTQSLEVLDLSNNAINEFKPQHLDCLHRLKTLNLAHNRLQYLQENTFDCVKNLEELNLRRNRLSWIIEDQSAAAPFKGLRKLRRLDLHGNNLKQISTKAMSGLNNLEILNLGSNALASIQVNAFEHMLRLNKLVFKSLNFICDCDLVWFQQWLKNRFPQQAEHAVCGYPEHLLDRHLKSLSSSELVCVDSPKPRVEQEPDDMLAVNAANITLECIASSPTAASLAAADELKIKWRHDNQHVQERPAVHDGASTETQIRHDLSTNQTSIYGYLRLTNVTYESAGRYQCVVSNAFGTTYAQKFKISIGIHPTFLQVPSNLTLDAGEMARLVCSASGDPTPEIALQKFGGSEFPAATERRLQVIREENAFLITNAKPSDSGIYTCTALSAAGEIKVNATLVVNDKPQPSIPLVHQEVVVGRTCVLQCLSETANADFELEHPHREWFKENKPIHISPTAPDGDRYYFSNNKELLVILNAQSNDAGHFRCEITDNS------------RTFTLQSELVVVKENLNWVVLLVGIITVTVICVVVDCCIIWCTLRYQKKKLR----------MSLAAERHSTQLRPRSLADLGCSYDEANHRRLTVMSTPPSEQRCLEQG-----LTLSYLRQTDLEAQQDHLSSKDSGTGSDAAVKR---TLDDFEVAMPSHKHHTDDEEEEEVEEVYEEN--------------------------EPPYIKHTYEVNYAEPEQHLFLQNNNHNYDGG--------GIGVAGGVNKMVPNALLRKCSAGASGSNYSS------------------------------IQQCTTVDI----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :.:* * :* .***. . . . . ** *:**. *:**.: :* *:* **::* *.*::*:*. . .: :* .* :*.*:.* **.**:: :*. : * **.* * .* .* * : *.***** * : **.: . :* :* :. *.::.:: * .* .* *:*..**:*::* ::** * **::* ** * ::: **:** ::*.*::: * : * **.*: : ::* ::* *:::.::: *:.* *:.*:** ***.**. *:*** *.*. ***: * :..:. . : * *::*::.:*::.*: : :* :..*: *:*:.*.:** *** .. .*.** :**:* *:**.::.*:.**::**: ** *:*..**: *:* ***.:* :*::* ::: .::***:* *: **: :. *. :* *.:*: * .* : ::*.. :** * ***:: :*: *::.::::: * *:*.: : :.: *::**: ::*. : : . : . *** :* : * *:****:** **::*: * ::::.: *:* :.* :**: ** **** *:* *.*:*:** ** ** :**** ***::*: *::.*:*.:.* .* *:*:*** .:**.:..****.* :.*. **:.: *. *.*.****:: : *: :* *::.*: :: :*::*: .::**:*:::: .***:: **:::. * * :* :.. . . **:: ::*:* **. .::* .: *:.:: . .*.*: * :*** .* .:: : *... * * :. ::*:** * : . .: . :: * **. .. . .. :. * * :: . :: * . : * *::. ::. . . .. * ..* : .. * *: .. .: .. : ** : ", "identical_positions": 305, "similar_positions": 382, "identity": "22.33%" }, { "cls_id": "homologset.agr.MGI:2443957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TSH3-1", "uniprot_id": "ZN516_MOUSE", "id": "Q7TSH3-1", "name": "Zinc finger protein 516", "aln": "MDRSREAEMELRRGPSPPRAGRSHEVDGDKAACHSCCICGKSFPFQSSLSQHMRKHTGEKPYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGHEPEAGEAQLGEMRVSEGLDGCASPTKSTSACNRVLNGAVPMDGS------------KILLRSSRKEVEGAASAQEDTEATVPCSFCKSRFERKKDLELHVHQAHKPFKCRLCSYVTLREESLLSHIERDHITAQVPNGSEACVENGKPELSPGEFPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFKEPWFLKNHMKAHGPKAGSKNRPKSELDPIATINNVVQEEVIVAGLSLYEVCTKCGNLFTNLDSLNAHNAIHRKVEASRIRAPAEEGDSEDPLDTKQFFLQCLNLTPYVAGDVSPGGQAGRRVAELDPVNSYQAWQLATRGKVAEPAEYLKYGTWDEALAGDVAFDKDKREYILVSQEKRKREQDAPATQAPPRKRASVPGDPMLSGHLDPRPTSRPNRRASATTGQGKSSECFECGKIFRTYHQMVLHSRVHRRARRDRDPEGDRAARARCGSLSEGDSASQPSSPGSACAIADSPG--LAEEVVDDSGEEAVPEPASGGQPRHCCSSGEVTPTALSNGDQNHKLGNNLPEKDISEPKVGSAMPSVSILENSSRETTKGPEQHRYSLDLKMPAFHPKQEVPSTTDRVDFPASMEITSLQHTLDSQAGHSKEKLSDLH-KEHCGVGKRASAPDLVPLDLSMRSSRDEPSGKE-ACSLQAALVIHPCPYCTHKTYYPEVLWMHKRIWHRVSCSSVAPPWTQPSGHKSIRSNLVFLTRSGRTGPPPALGGKECQPLLLSRFARTQVPGGAPGSKGSSSPLGVTTKAASMPKNKESHSGGPCALWASGPDGYRQTRAGHGQEPPSAAVQGPLAKPKQEGSSRLAPSPGSGSLSRSTTPTPSVITRVGAQPSANSKPVEKLGGPAVGTGFTPPNKHSAPDSLKAKFSPQPQGQPPLKGEGGSP-LPPREPSVKAAQELRTLATCAAGSRGEAALQAPP---GAPPTLNSAKQEP-AAEGQEKRLDILSIFKTYIPKDFATLYQGWGVSSPGPEHRGTSLTGTPRTQAHQGDFVCVECGKSFHQPSQLRAHLRAHT-----VVFECDG---------------PRDSEVHTASTDAPKQGRDHTTPG---------------TVPAGPLRKGI---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LHI7-1", "uniprot_id": "A0ABK0LHI7_RAT", "id": "A0ABK0LHI7-1", "name": "Zinc finger protein 516", "aln": "MDRSREAEMELRRGPSPPRAGRSHEVDGDKAACHSCCICGKSFPFQSSLSQHMRKHTGEKPYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGHEPEVGEAQLGELRVSEGLDGCASPTKSTSACNRVLNGAVPTDGS------------KILLRSSRKEAEGAASAQEDAEAMVQCSFCKSRFERKKDLELHVHQAHKPFKCRLCSYVTLREESLLSHIERDHITAQVPNGSEACVENGKPELSPGEFPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFKEPWFLKNHMKAHGPKAGSKNRPKSDLDPIATINNVVQEEVIVTGLSLYEICTKCGNLFTDLDSLNAHNTVHRKVEASRNPAPAEEGDTEDPPDTKQFFLQCLNLTPCVAGDVSPSGQAGRRVAELDPVNSYQAWQLATRGKVAEPAEYLKYGTWDEALAGDVAFDKDKREYILVSQEKRKRESDAPSTQAPPRKRASVPGDPMLSGHLDPRPASRPNRRAAATTGQGKSSECFECGKIFRTYHQMVLHSRVHRRARRDRDPEGDRAVRARCGSLSEGDSASQPSSPGSACATADSPG--LAEEVVDDSGEEAVSEPASGGQPGHCCSSGEVAPILLSNGDPSHKLGNNLPEEDISEPTVGIATPSVSILENSSRETTKGPEQHRHSLDLKMPAFHPRQEA-STPERVDFPSSMEIASLQHTLDSQAGHSKEKLSDLH-KEHCGVGKRASAPDLVPLDLSMKSSREDPSSKE-ASSLQTALVIHPCPYCNHKTYYPEVLWMHKRIWHRISCGSIAPPWTQPSGHKSICSNLAFLARSGRTGPPPALGGKDCQPLLLARFTRTQVPGGVPGSKGSSSPLGVTTKAASIPKNKESPSGGPCAPWAPGPDGYRQTRAGHGQDPPSAAVQGPLPKPKQEASSRLAPSPGSGGLSRSATPTPSVITRVGAQPSANSKPVEKLGVPAVGTGFTPPNKHSAPDSLKAKFSPQPQGQPPSKGEGGSP-LPPREAPVKPAQELRTLATCAAGPRGDAALQAPP---GAPPTLHSIQQEPAAAEGQEKRLDILSIFK-YIPKDFATLYQGWGVSSPGPEHR-----GTPRTQARQGDFVCVECGKSFHQPSQLRAHLRAHTGERPHCPRDCAGRAPPKGDLETHLQHPARDSVDCGLTGDWKAPSSDHGHFGEEDPSSLRSPSPWCRPVPCFPLPSETKIHPGALLWLSSYNPVHLPRRDEYLPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92618-1", "uniprot_id": "ZN516_HUMAN", "id": "Q92618-1", "name": "Zinc finger protein 516", "aln": "MDRNREAEMELRRGPSPTRAGRGHEVDGDKATCHTCCICGKSFPFQSSLSQHMRKHTGEKPYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGHEPEAGEAPLGEMRASEGLDACASPTKSASACNRLLNGASQADGARVLNGASQADSGRVLLRSSKKGAEGSACAPGEAKAAVQCSFCKSQFERKKDLELHVHQAHKPFKCRLCSYATLREESLLSHIERDHITAQGPGSGEACVENGKPELSPGEFPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFKEPWFLKNHMKAHGPKTGSKNRPKSELDPIATINNVVQEEVIVAGLSLYEVCAKCGNLFTNLDSLNAHNAIHRRVEASRTRAPAEEG-AEGPSDTKQFFLQCLNLRPSAAGDSCPGTQAGRRVAELDPVNSYQAWQLATRGKVAEPAEYLKYGAWDEALAGDVAFDKDRREYVLVSQEKRKREQDAPAAQGPPRKRASGPGDPAPAGHLDPRSAARPNRRAAATTGQGKSSECFECGKIFRTYHQMVLHSRVHRRARRERDSDGDRAARARCGSLSEGDSASQPSSPGSACAAADSPGSGLADEAAEDSGEEGAPEPAPGGQPRRCCFSEEVTSTELSSGDQSHKMGDNASERDTGESKAGIAA-SVSILENSSRETSRRQEQHRFSMDLKMPAFHPKQEVPVPGDGVEFPSSTG-------AEGQTGHPAEKLSDLHNKEHSGGGKRALAPDLMPLDLSARSTRDDPSNKETASSLQAALVVHPCPYCSHKTYYPEVLWMHKRIWHRVSCNSVAPPWIQPNGYKSIRSNLVFLSRSGRTGPPPALGGKECQPLLLARFTRTQVPGGMPGSKSGSSPLGVVTKAASMPKNKESHSGGPCALWAPGPDGYRQTKPCHGQEPHGAATQGPLAKPRQEASSKPVPAPGGGGFSRSATPTPTVIARAGAQPSANSKPVEKFGVPPAGAGFAPTNKHSAPDSLKAKFSAQPQGPPPAKGEGGAPPLPPREPPSKAAQELRTLATCAAGSRGDAALQAQPGVAGAPPVLHSIKQEP-VAEGHEKRLDILNIFKTYIPKDFATLYQGWGVSGPGLEHR-----GTLRTQARPGEFVCIECGKSFHQPGHLRAHMRAHS-----VVFESDG---------------PRGSEVHTTSADAPKQGRDHSNTG---------------TVQTVPLRKGT---------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.*************.****.********:**:*************************************************************.*** ***:*.*****.*******:*****:**** **: ::*****:* .**:*.* :::* * ******:*************************.******************* *...*********************************************************************:********:*****************:******:*:*******:********::**:***** ****** :*.* ************ * .*** .*. ************************************:**************:***:**********.***::*.******* **** :******.::******:************************************:**.:****.************************ ***** **:*..:*****...***.**** :** * **:. **.** .**:*:* .*.* .*...* * ************:: ****.*:*********:**. . : *:**:* :.*:**. ******* ***.* **** ****:***** :*:*::**.** *.***:***:******.******************:**.*:**** **.*:*** ***.**:**************:******:**:******* ****..******.*****:****** ****** **.********:. ***:* .**.****.**:**.**: .*:**.*.:***:****:**:*.*************:* *..*:**:*.**************.**** ** *****:* *****.. *.*************.**:***** * ****.*:* :*** .***:*******.*** ****************.** *** ** ****: *:***:*********.:****:***: :. * .*.* : * . ** * .* ** . ", "identical_positions": 887, "similar_positions": 170, "identity": "71.53%" }, { "cls_id": "homologset.agr.MGI:2443963", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y244-1", "uniprot_id": "A0A8I5Y244_RAT", "id": "A0A8I5Y244-1", "name": "", "aln": "MLDPSSSEEESDE-------------GLEEESREVLVAPGGS--------------------QRAPPATAREGRRDAP--------------------------------------------GRSGGGGGGGAARPVSPSPSVLSEGRDEPE---RQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCCANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGE-EDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERR-FPQFISKEMETMYIEELRASVNLLMANLESLPVSKG--GPEFKLQKLKRSQNS--AFLDLG--------------DENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFSTTHPRPVVKVKLFTESTGVLALEDKELGRVVLYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPPHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPG-------LQGGQVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAVQSQKLNPKGGTLHADAQLY---ADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERFEEIKDRLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMN---QATPARKLEEVLHLAELCIEVLQQNEEHHA---------------------------------------------------------------------EAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWESFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQP-----------VKNIANSLPNVALP-------KVPSLPLNLPQIPSFSTPPWMASLYESTNGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQK--ANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFGNQWQQYHSKIDDLIDNTVKEVIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQG---ITMKDSDEEEEG-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYR5-1", "uniprot_id": "CAPS2_MOUSE", "id": "Q8BYR5-1", "name": "Calcium-dependent secretion activator 2", "aln": "MLDPSSSEEESDE-------------GLEEESREVLVAPGVS--------------------QRAPPAAAREGRRDAP--------------------------------------------GRSGGGSGGGAARPVSPSPSVLSEGRNEPE---LQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGE-EDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERR-FPRFISKEMESMYIEELRASVNLLMANLESLPVSKG--GPEFKLQKLKRSQNS--AFLDLG--------------DENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFNTTHPRPVVKVKLFTESTGVLALEDKELGRVVLYPTSNSSKSAELHRMTVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPG-------LQGGQVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAVQSQKLNPKGGALHADAQLY---ADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERFEEIKDRLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMN---QATPARKLEEVLHLAELCIEVLQQNEEHHAEGR------------------------------------------------------------------EAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQP-----------VKNIANSLPNVALP-------KVPSLPLNLPQIPSFSTPPWMASLYESTNGSTTSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQK--ANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQE-----QQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQG---ITMKDSDEEEEG-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UW7-1", "uniprot_id": "CAPS2_HUMAN", "id": "Q86UW7-1", "name": "Calcium-dependent secretion activator 2", "aln": "MLDPSSSEEESDE-------------GLEEESRDVLVAAGSS--------------------QRAPPAPTREGRRDAP--------------------------------------------GRAGGG---GAARSVSPSPSVLSEGRDEPQ---RQLDDEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGE-EDLCKQPNRMALSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERK-FPKFIAKDMENMYIEELRSSVNLLMANLESLPVSKG--GPEFKLQKLKRSQNS--AFLDIG--------------DENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEG-EKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPG-------LQGGCMFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTLHADAQLSGKDADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMN---QASPARKLEEILHLAELCIEVLQQNEEHHAEGR------------------------------------------------------------------EAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHRGFEQETWQP-----------VKNIANSLPNVALP-------KVPSLPLNLPQIPNISTASWMPSLYESTNGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQK--ASKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQE-----QQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVHRRLTVEEATASVSEGGGLQG---ITMKDSDEEEEG-----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NHE5-2", "uniprot_id": "CAPS_DROME", "id": "Q9NHE5-2", "name": "Calcium-dependent secretion activator", "aln": "MIDPSSSEEEGEDDAVPNVSSKGRLTNTTKGTSAVSIIGGSAGSVVGSNIPVSGSNTDLIGNQRQSNISSICNRNDVGNISVAALGSTSNKIEQICGNRADTGNLEVPSNGIPSGISQETLNQSVGSSRANSLPRPLSPSPSLTSEKHETAEPHGKHEREEEERKRRIQLYVFISRCISYPFNAKQPTDMTKRQTKISKQQLEIITQRFQAFLKGETQIMADEAFQNAVQSYHDVFLKSERVLKMVQSGASSQHDFREVFRNNIEKRVRSLPEIDGLSKETVLTSWMAKFDIILKGTGEEDSKRPSRMQQSLNSELILSKEQLYDMFQQILLVKKFEHQILFNALMLDSADEQAAAIRRELDGRMQRVGEMEKNRKLMPKFVLKEMESLYVEELKSSINLLMANLESLPVSKGNMDSKYGLQKLKRYNHSTPSFLKLILRSHGSLSKLEGDSEDGSTQLTKLDVVLTFQLEVIVMEVKGLKSLAPNRIVYCTMEVENGEKLQTDQAEASKPMWDTQGDFTTTHPLPVVKVKLYTENPGMLALEDKELGKVTLKPTPLSSKSPEWHRMIVPKNLPDQDIRIKIACRLDKPLNMKHCGYLYAIGKSVWKKWKRRYFVLVQVSQYTFAMCSYKEKKSEPSEMMQLDGYTVDYIEAASANLMFGIDLNGGRYFFNAVREGDSISFACDDENECSLWVMAMYRATGQSHKPTPPIT-QDKNSAMSKIQGD-------ADKARKHGMEDFISTDPCTFDHATLFKTLQNLTLEYRLNDPYASLGWFSPGQVFVLDEYCARYGVRGCYRHLCYLSDLLDRAEKQHMIDPTLIHYSFAFCASHVHGNRPDGVGSITHEEKEKFSEIKERLRQLLEFQITNFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPPEEVRQMIKKSLETAALVNYTRLSNKAKIDEDLRGDVIVPAPKKLEDLIHLAELCVDLLQQNEEHYGELRKHDKMDKKKLLKEDEDVSGGHNESEVDLIDSTGLISASELATAASTDGSSFRYCMPTHAVYTPPVPTAFAWFSDLLVEHAEIFWSLFAVDMDRVLSEQAPDTWDSFPLFQILNDYLRTDDNLRNGRFHQHLRDTFAPLVVRYVDLMESSIAQSIHKGFEKERWESKGINAALNPAALNNAAQALNTAALNPSMILCGKKDQVNFYVPKLPKQSNS--TAANDEMRNGCATSEDLFWKLDALQSFIRDLHWPDAEFRQHLEQRLKMMAVDMIEQCIQRTDSSFQSWLKKNIAFISTDYILPSEMCAMVNVILDAKNQSFKLTTIDGIDL-----YKFHAKIDDQIDKANVAMTQGLSGKLMSVLESTLSKLARYDEGSLIGSILSFTN--------VSSSGKDLGQGYVNFFRNNMDQVRGKIADDLWTLHFFEQWYSQQINMLCNWLSERVDHALHYAQVASISHIIKKIYSDFELQGVLEDKLNSKAYQAVAQRMATEEATCALTMPDACEDEPCDEIREGEEEDNGDESTSNIPRGLPKPKVAAAQAAAVTNVVAGRVGNLLGKGIGGLSSKLGSGSWF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:********.:: . : : * : * : ** . .: .*.*. *.. . .*.:*****: ** :: .: : :*:**: *:*****: ***:***********::** *:.****:::.:******:*****:***** ***:**::*****:** :*****... :******::*********************:**:**:* * :* *: .*:*.** * ***********:****** :**:***:*:** **.****** ********:* . :* *:*: :*:*: *:**.:*:***::*:*************** ..:: ****** ::* :**.: ::.. **:* ****:* **:::***:****:*************. ***********:* *.*****.**** *******:**..*:*********:* * **. ****.* *** **** *.*::**:* *:*** :***.*****:*:.***:**:******************:******.*:***:****** :. .. *:** *****:***:: **.***:: *** *********:**.*.: *. *. . ::.* **: :****::***:.**.:*** **: **. **::****.*:.************************:******::*::::*: :*****:******************:*::: ****:*.***:** .*** **::*****************************.**:*.***:::::*.**.***:*****:: ***:* :. ....:***:::******:::*******:. ****:.***.**** **:**:**** .*. *. *:*:******:**::**.* * **:**:**:: *.************:******:***:* *:. ::* *::* ..** * .: : :*::*. *.. .: * **.:************* *: *****: ** :*******:** **:* *::** ::*: *:* * :** :*:.:*:*.**::***:** ** ::** : ::*:**** **:: : * .*::****..****:*****:::.****** *...* **.: *: *.*:* * :* *: :::: ::*:****..::::* **::*:* ** *: :: :*:** * **.******..****:*::: :*::.****.::: .. :. :::.:**::* ", "identical_positions": 756, "similar_positions": 356, "identity": "48.55%" }, { "cls_id": "homologset.agr.MGI:2443965", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5DT36-1", "uniprot_id": "KLRI2_MOUSE", "id": "Q5DT36-1", "name": "Killer cell lectin-like receptor subfamily I member 2", "aln": "MHKKKHIKHGTNKQEIINIGTKSPTFQEKQRPSKTDQRSTVWREEQKKQELKVHRIFHPQPRTGFDVGKGIDPWLTTWQMITVILATLCIILVTKVGFLIPS----LFSKGEKQSRKFSLLDPLCDRNDDSSCDFCSSDWIAFGNNFYCVFRENSKTWVESQSACEELNSHLVIIDSKAEVENLLLFEMDG--WI----LHRMDGTNSSRLWGNDIKIRNTLMNDSEKKNHSCHYLRGNIFMPDECSAKKTYICEFNI--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5DT37-1", "uniprot_id": "KLRI2_RAT", "id": "Q5DT37-1", "name": "Killer cell lectin-like receptor subfamily I member 2", "aln": "MPRKKQNERGTNKQEIINIETKSSTFQEKQRQSKTDQISTVWRKEQKKQELKVHTELHPQHRTGFNEDKGTDPWLTTWRIITVILGTSCIILVTKVGFLIPN----LFSRGEKRSRELSLLDSLCLKNNDSFCDLCSHDWIAFGNNFYLFFR-GTKTWAESKSACEELNSYLLDIDSRAELENLLLFEING--WI----LFKTDAINRS-LRKNYIKIHQTLFNDSEKKNHSCHYLSGNQFSAGDCSSKKAYTCEFNLQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O46197-1", "uniprot_id": "A29AB_DROME", "id": "O46197-1", "name": "Accessory gland protein Acp29AB", "aln": "-------MYASNLLYLLALWN-------------------LWDLSGGQQDIPNGKATLPSPQTPQNTIDQIGINQNYWFTYNALKQNETLAIIDTMEMRIASSLLEFKAQMEIQLQPLKIIMRHHASNIKASNNIKMRRFEKVGSRHFHIEKNLMQTWFEAYVTCRKMNGHLANIQDEMELDGILALAPNNSYWIDISKLVENGGTFVSTLTGREPFFVKWKSNQDTKKKNQCVYIYAKEMSYDECFEKKSFVCQADQWA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* :: : . :* . :*:: *. :* : . . . * ..: . : :: .: : *.. : :: * : : :.:: * .: :: : .*...: . : :** *: :*.::*.:* *:.. *::.:* : :. ** * . .. * * . : : *:. **::.* *: .: : .:* **:: *: : ", "identical_positions": 33, "similar_positions": 89, "identity": "12.69%" }, { "cls_id": "homologset.agr.MGI:2443967", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GBE0-1", "uniprot_id": "A0A8I6GBE0_RAT", "id": "A0A8I6GBE0-1", "name": "dipeptidyl-peptidase IV", "aln": "------------------------------------------------------------MDLGSALTLSNQKPPLPGQRRRSCRVPGVRRLRCPPAPATSGPSSWAWSVACEAPPALGTPCPACPPRRARVRTPRLQLPWKLLGPFRSFSPPSQEPQRMSGGVSPVEQVAAG---------------------------------DMDDTAAR-----FCVQKHSWDGLRNIIHGSRKSSGLIVSKAPHDFQFVQKPDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLS---------------------------------------WKQMLDH-FQATPHHG------VYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVS-PMKPLEIKTQCSGPRMDPKICPADPAFFSFINNNDLWVANIETGEERRLTFCHQGSASVLDNPKSAGVATFVIQEEFDRFTGCWWCPTASWEGSGGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAELQTDHQGKIVSSCEKELVQPFSSLFPKVEYIARAGWTRDGRYAWAMFLDRPQQRLQLVLLPPALFIPTLESEAQW-------QEAARAIPKNVQPF-IIYEEVTNVWINVHDIFHPFPQAEGQQDFCFLRANECKTGFCHLYRVTV-DLKTNDYDWTEPLSPAED-------EFKCPIKEEVALTSGEWEVLSRHGSKIWVNEQTKLVYFQGTKDTPLEHHLYVVSYESAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHK--QPRFWASMMEAASCPPDYVPPEIFHFHTRADVQLYGMIYKPHTLQPGRKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLHFEGALKNQMGQVEIEDQVEGLQYVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQQGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCRESGEHYEVTLLHFLQEHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVG4-1", "uniprot_id": "DPP9_MOUSE", "id": "Q8BVG4-1", "name": "Dipeptidyl peptidase 9", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MCSGVSPVEQVAAG---------------------------------DMDDTAAR-----FCVQKHSWDGLRSIIHGSRKSSGLIVSKAPHDFQFVQKPDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLS---------------------------------------WKQMLDH-FQATPHHG------VYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVS-PMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGSAGVLDNPKSAGVATFVIQEEFDRFTGCWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAELQTDHQGKIVSSCEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQRLQLVLLPPALFIPAVESEAQR-------QAAARAVPKNVQPF-VIYEEVTNVWINVHDIFHPFPQAEGQQDFCFLRANECKTGFCHLYRVTV-ELKTKDYDWTEPLSPTED-------EFKCPIKEEVALTSGEWEVLSRHGSKIWVNEQTKLVYFQGTKDTPLEHHLYVVSYESAGEIVRLTTLGFSHSCSMSQSFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHK--QPRFWASMMEAANCPPDYVPPEIFHFHTRADVQLYGMIYKPHTLQPGRKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLHFEGALKNQMGQVEIEDQVEGLQYVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQQGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCRESGEHYEVTLLHFLQEHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TI2-1", "uniprot_id": "DPP9_HUMAN", "id": "Q86TI2-1", "name": "Dipeptidyl peptidase 9", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MATTGTPTADRGDAA---------------------------------ATDDPAAR-----FQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLS---------------------------------------WKQMLDH-FQATPHHG------VYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVS-PMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQR-------LASARAVPRNVQPY-VVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTA-VLKSQGYDWSEPFSPGED-------EFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHK--QPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QP51-1", "uniprot_id": "DPP9_DANRE", "id": "A0A2R8QP51-1", "name": "Dipeptidyl peptidase 9", "aln": "----------------------------------------------------------------------------------------------------------------------------------MYRGKRVKLEDETEG-----SWKSFAAVRMTAVDDISDSTEVV---------------------------------EMEDVPSQ-----FFVEKHSWDGLRDIIHNSRMYSGMVINKAPHDFQFVQKHDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKIRKEALLVLS---------------------------------------WKQMLDH-FQATPHHG------VYSREEELLRERKRLGVFGITSYDYHAQSGLFLFQASNSLFYCRDGGHNGFIQAAPMKPMEIKTQCSGIRMDPKISPGDPSFIAFINNNDLWVTNIETAEERRLTFCHKGLNNVKEDPKSAGVATFVIQEEFDRFTGYWWSPAAT-EDADGGKTLQLLYEEVDESEVEIIHVPSPALEERKADVYRYPRTGSKNPQISLKLAEIRTDQQGKMISAQNKELVLPFTTLFPGVEYIARAGWTKDGKFAWAVLLDRSQQKLQLVLLPPALFIPVSVDDPQW-------EEHVEAMPEGVQPF-IIYEEITDIWINVHDIFYPFIQTS-NDKISFLWVNESQTGFCHLYRITS-LLKPGCHQWSREYSPSED-------DFKCSTEEEVALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYESPGEIVRLTKPGFSHSCSVSQNFDMFISHYSNVSTPPCVHVYKLTGADSDPLHK--EPEFWASMMEATGCRPDYIPPEIFSFPASSGFRLYGMLYKPHNLKPGKKHPTILFVYGGPQVQLVNNSYKGVKYLRLNTLASLGYAVVVIDGRGSCQRGLKFEGALKNKMGQVEIEDQVEGLQFVAEKYKFIDLSRVAIHGWSYGGFLSLMGLIHRPNIFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQQGYEAGSVALHVDKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEIMLLYFLQQHL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC19-1", "uniprot_id": "Q9VC19_DROME", "id": "Q9VC19-1", "name": "Dipeptidyl peptidase 9", "aln": "MESRTQMNQSNQQQQQQRNRLPSSPSPPLSVVSLTGGPNANTTLMGLEHDAVPSSQLGRNNNNGGGHHRSHSITNAATTSLANLLDGFTARVSTAVSVAGGTNMLMDRSSQSAASTPGSTHSIASLTSMGSLGTTANALYSSIGSALNSITSPIQAAAAAATATTTEVVVAAASVITNHLSSPTSGTPPHGLDVDEGDDECDDCEEDEDDPVDNDGHIAAPTPNKSWAENKQVVQEIRKKMCNLSSMVPTNVQFRHLSDGR----ARCYFLGTPPQSWETTLLFADINLTQSEEQQLLVQRLEGIASDEWSPTMNAGSPTSSGHQPAFLFNSLPRPRLPWSPLLQQPIQSSGGSGGSGSASPYAREYQLLQERKRLSTWGITSYELHKPSGKLVFPCFNDLYQCLDTGYN----SGLLFPTQLRTCPQWTALDPQICPQNSDMIAYISDCDLFVTHTLSGHEKRLTYTSTGRHSYVDDALSAGVPSYVMQEEFSRYQGFWWQPHSN----DG--IYRIVYEEVDESEVSVYTFPSSTAMHGRVDEYRFPRTGSPNAKSKLKLVQFVLNEALQVSEIAIKDLPYSLLAVFSWLEYIVRVGWTPDAKYVWVQGLDRKQQRLDVILIPLDNFCESYSSQVSTPTDSIGDHSWRSLYSRTITPLQVIYTERSDSWINVHDMLHFLDLTE--TSVTFLWASE-ETGFRHLYLVTASLLLSQANGQPDPGSVGAQPSFVDLSALQPRILNKVALTSGEWEVLARN---LWVDKANKLVYFVGLRDTPLEKHLYVVSLERPEHIRLLTEPGYSYLVEFDDQCKLMLLVYCNIQRLPSCKVMRVNQTCSNGGVNGIQISLVGYLHEGGKPEPQYCP-QIFSPQLPSGDIVYAMVFKPHNFELGVKYPTVLNVYGGPEVQTVNNTFKGKHQLRMHMLAAQGYCVICIDSRGSRHRGKRFESHIRGRMGQVELTDQVDALRSLSDQLGYIDMDRVAIHGWSYGGYLSLMGLVQYPKIFKVAIAGAPVTNWEYYDTGYTERYMDMPQNNEAGYSAGSVLEYVNSFPEEDKRLLLIHGLIDENVHFCHTSRLISALNKANKPYEVHLFPEERHSLRNLESNKNYETKLLSFLQNL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 326, "similar_positions": 266, "identity": "29.0%" }, { "cls_id": "homologset.agr.MGI:2443972", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62825-1", "uniprot_id": "EXOC3_RAT", "id": "Q62825-1", "name": "Exocyst complex component 3", "aln": "MCKDSACFSTMKETDLEAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQG-----------ALLQAHRKLMDLECSRDGLMCEQYRMDSGNKRDMTLIHGYFGSTQGLSDELAK---------------QLWMVLQRSLVTVRRDPTLLVSVVRIIERE----EKIDRRILDRKKQTGFVPPGRPKNWKEKMFAVLDRTVTTRIEGTQADTR--------------------ESDKMWLVRHLEIIR--KYVLDDLVIAKNLLVQCFPPHYDIFKNLLSMYHQALSIRMQDLASEDLEANEIVSLLTWVLNTYTSAEMMGNVELAPEVDVNALEPLLSPNVVSELLDTYMSTLTSNIIAWLRKALETDKKDWSKETEP-EADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSR---------------YKEEAQLYKEEHLRNRQHPHCYVQYMVAIINNCQTFKESIISLKRKYLKPETEESLCQSQPSMDGILDAIAKEGCSS---LLEEVFLDLEQHLNELMTKKWMLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSAEERKEGAEKMVREAEQLRFLFRKLASGFGEDADGHCDTIVAVAEVIKL--TDPSLLYLEVSTLVSKYPDIRDDHIGALLALRGDASR-DMKQTIMETLE-QGPMQASPNYVPIFQEIVVPSLNVAKLLK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6KAR6-1", "uniprot_id": "EXOC3_MOUSE", "id": "Q6KAR6-1", "name": "Exocyst complex component 3", "aln": "MCKDSACFLTMKETDLEAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQG-----------ALLQAHRKLMDLECSRDGLMCEQYRMDSGNKRDMTLIHGYFGSTQGLSDELAK---------------QLWMVLQRSLVTVRRDPTLLVSVVRIIERE----EKIDRRILDRKKQTGFVPPGRPKNWKEKMFAILDRTVTTRIEGTQADTR--------------------ESDKMWLVRHLEIIR--KYVLDDLIVAKNLMVQCFPPHYEIFKNLLSMYHQALSTRMQDLASEDLEANEIVSLLTWVLNTYTSAEMMGNVELAPEVDVSALEPLLSPNIVSELLDTYMSTLTSNIIAWLRKALETDKKDWSKETEP-EADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSR---------------YKDEAQLYKEEHLRNRQHPHCYVQYMIAIINNCQTFKESIISLKRKYLKTEAEEGLCLSQPSMDGILDAIAKEGCSS---LLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSAEERKEGAEKMVREAEQLRFLFRKLASGFGEDADGHCDTIVAVAEVIKL--TDPSLLYLEVSTLVSKYPDIRDDHIGALLALRGDASR-DMKQTIMETLE-QGPMQASPNYVPIFKEIVVPSLNVAKLLK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60645-1", "uniprot_id": "EXOC3_HUMAN", "id": "O60645-1", "name": "Exocyst complex component 3", "aln": "----------MKETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQG-----------ALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHGYFGSTQGLSDELAK---------------QLWMVLQRSLVTVRRDPTLLVSVVRIIERE----EKIDRRILDRKKQTGFVPPGRPKNWKEKMFTILERTVTTRIEGTQADTR--------------------ESDKMWLVRHLEIIR--KYVLDDLIVAKNLMVQCFPPHYEIFKNLLNMYHQALSTRMQDLASEDLEANEIVSLLTWVLNTYTSTEMMRNVELAPEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVKETEP-EADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSR---------------YKDEAQLYKEEHLRNRQHPHCYVQYMIAIINNCQTFKESIVSLKRKYLKNEVEEGVSPSQPSMDGILDAIAKEGCSG---LLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSPEERKEGAEKMVREAEQLRFLFRKLASGFGEDVDGYCDTIVAVAEVIKL--TDPSLLYLEVSTLVSKYPDIRDDHIGALLAVRGDASR-DMKQTIMETLE-QGPAQASPSYVPLFKDIVVPSLNVAKLLK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V8K2-1", "uniprot_id": "EXOC3_DROME", "id": "Q9V8K2-1", "name": "Exocyst complex component 3", "aln": "--------MDLQQLEEQARQAALKDIQNMLQRPGQLEKVEQYRHRIARKKASVEALLKTGMQGQLDGVRVGLKQLETCMQDVREVRRRMDEVERLLRGVPEVYDALEVVREENTKHSQYATAMENLKHIFNVDASVQKTMALIEDD-----------KLLNAHQCLADLENSRDDLLYELHKQPKQHASDKITLKRHFEKVDTVSQELEK---------------KLRLILSRTLNTLRKKPTIIVTALRIIERE----EKNDQFALQQQKVTGFLPPGRPKAWRRMIMDVLQQSVITRIEGSKLEER--------------------ADNKMWLVRDLEILR--QIILEDLRVVKSLCVPCFPPHYDIFGEYVKFYHEGLSSYLDNIVRSGLEGNEYVSMMAWVTHTYPGVELMSHPDLNVDVHR-QIGTLLRPEHLKALEDEYLQNMQRNFQEWMTKAAETEKQEWFTETVP-DQDEE-YYHTSAPVIIFQMIDQHLQVTNTIHQELTFKALVMSIQQVEIFGQT---------------YLKNVIELKEHHFRNRDQIKYFTHYIITIVNNSQQMVELAQQMKQLYWPKSRTEHYEDFER-LLATFQRIRAHAASY---LLEEAFLDMECHFNDLFTAKWLASNIAVDTICVTLDDYFQDYNHLRPNNFEMVINEAQKLLAKRYIRALLSKRLS-KPRAECDAITRKIKTEAKRFKLFFEKIAPKISLS-DSPLDLISTLSALLS---SDIELLVLDLHTLLGSYPSLNEDHLVRLFYIRNDVKAAEVREKVQDAMKSKKAMVSIAKQDCIFKEIVFS----DKLW--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32844-1", "uniprot_id": "SEC6_YEAST", "id": "P32844-1", "name": "Exocyst complex component SEC6", "aln": "-----------------MSSDPLQQVCDLIKGDLSLERVRDIKEQLLKEKSVVEYQLNKESDKYYGEVEESLKLLNLSKNSVTSIKQQINEVNKLGNDNRFAINRYDILFRATKLYETVNTTSSIYDRIYNFVALMEHIERLLVAELAEDALETGCPHLLEIHFLLTSARDFQEQVVVMAKEATEDAQRTVMKLFSRLSGIISKFDKLLDGLTYDIVEMARAEQISLAIRLFKIYDLEEREDLRIEAIRNIIKKKEIEIEKSSIKKLPNSKNTARLQDETPKVIEYPTNKGLYQEIMSGTISTRTAPRGYKHFLINGINNSISEMFGEMREKYVGDQKFDVLDNMDWIFNELIIVKEHIANCCPPHWNIFEVYFDQYYKELHSLITDLVESEPETIIILDILAFDK------TFQDTLKQDFGFTKSEVKSVIGDKEKETLFKDYLNLIVVKMTEWIGNLEKAEFDVFLERSTPPHSDSDGLLFLDGTKTCFQMFTQQVEVAAGTNQAKILVGVVERFSDLLTKRQKNWISKISEEIKKQINYNHKYDIDPESITPEDECPGGLVEYLIAVSNDQMKAADYAVAISSKYGKLVSKVYEKQITNHLEGTLDGFAEVAQCSSLGLITLMFDDLRKPYQEIFSKTWYMG-SQAQQIADTLDEYLLDIKPQMNS--VLFVNFIDNVIGETIIKFLTALSFEHSFKNKNNKFLEAMKRDFEIFYQLFVKVLDGNESKDTLITQNFTVMEFFMDLSCEPIDSILDIWQKYLEVYWDSRIDLLVGILKCRKDVSSSERKKIVQQATEMLHEYRRNMEANGVDREPTLMRRFVLEFEKQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: : .::: .*::*.: :.: ::*: ** *: : . *. .*. *. . :.* .::: : :*.: . . : . : :. :: . ..*:.. :.. *: **: * * . . :: :: . . : : ::* . .* : * : .:. : : .**::: ** . * ..* *. : ** . * : : : .:: * :* :.:::: . ::::* :.*. . * ***::** .. *:: * : ::. . * :.:::: : . . : .:: . . * . *:. : :: *: : ::: . : .: * . *.: . ***: *:::*: : :* :.:: . * .: * : : ..*:::: *: : :. * : . :: : . . *: * *:. ::::: .* . .: *. *:::*: * . .. : :: : :. : . . : : : : :* *: . : : .: .:. . : . : * . . * : :: * *.. : :: : :: : . : :: .. :: ", "identical_positions": 73, "similar_positions": 257, "identity": "8.78%" }, { "cls_id": "homologset.agr.MGI:2443973", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LPZ0-1", "uniprot_id": "A0ABK0LPZ0_RAT", "id": "A0ABK0LPZ0-1", "name": "Cyclic AMP-responsive element-binding protein 5", "aln": "MIYEESKMNLEQERPFVCSAPGCSQRFPTEDHLMIHRHKHEMTLKFPSIKTDNMLSDQTPTPTRFLKNCEEVGLFSELDCSFEHEFRKAQEEESSKRNISMHNTVGGTMTGPGAHQLGSSRMPNHDTSVVIQQAMPSPQSSSVITQAPSTNRQIGPVPGSLSSLLHLHNRQRQPMPASMPGTLPNPTMPGSSAVLMPMERQMSVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAALTHHPAAMSNGNMSTIGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAH-HQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQNEVSMLKNEVAQLKQLLLTHKDCPITAMQKESQGYLSPESSPPASPVPACSQQQVIQHNTITTSSSVSEVVGSSTLSQLTSHRTDLNPIL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1L0-1", "uniprot_id": "CREB5_MOUSE", "id": "Q8K1L0-1", "name": "Cyclic AMP-responsive element-binding protein 5", "aln": "--------------------------------------------------------------------------------------------------MSMR-----------------------------------------------------PVPGSLSSLLHLHNRQRQPMPASMPGTLPNPTMPGSSAVLMPMERQMSVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAALTHHPAAMSNGNMSTIGHMMEMMGSRQDQTPHHHLHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAH-HQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQNEVSMLKNEVAQLKQLLLTHKDCPITAMQKESQGYLSPESSPPASPVPACSQQQVIQHNTITTSSSVSEVVGSSTLSQLTTHRTDLNPIL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02930-1", "uniprot_id": "CREB5_HUMAN", "id": "Q02930-1", "name": "Cyclic AMP-responsive element-binding protein 5", "aln": "MIYEESKMNLEQERPFVCSAPGCSQRFPTEDHLMIHRHKHEMTLKFPSIKTDNMLSDQTPTPTRFLKNCEEVGLFSELDCSLEHEFRKAQEEESSKRNISMHNAVGGAMTGPGTHQLSSARLPNHDTNVVIQQAMPSPQSSSVITQAPSTNRQIGPVPGSLSSLLHLHNRQRQPMPASMPGTLPNPTMPGSSAVLMPMERQMSVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAALTHHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAH-HQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQNEVSMLKNEVAQLKQLLLTHKDCPITAMQKESQGYLSPESSPPASPVPACSQQQVIQHNTITTSSSVSEVVGSSTLSQLTTHRTDLNPIL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5W2-1", "uniprot_id": "A0ACD6B5W2_DANRE", "id": "A0ACD6B5W2-1", "name": "", "aln": "-------MNSEQERPYVCSAPGCSQRFPTEDHLMIHRHKHEMTLKFPSIKNDNMLSDQTPTPTRFLKNCEEVGLFSELDCSIEQEFCKAQEEEDSKQNITLHG-----QGGPNQHQQAHSRMTNHDS-IVIQQALPSPQSSSVITQAPSTNRQIGPVPGSLSSLLHLRNRQRQPLPASMPGTLPDPTMQGSSAVLMPMERQMSMGSNMMGMQGPAHNNSCSSPHVPSMHSEAKLRLKAALAHHPGGMANGSMNSMGHMMEMMPSRQDQTGHHHMHSHPHQHMQGPPHG-YPHHGHHHPSHAQSVHHHPQSHGHHNSHP-AHMHPAHGHQTSPHQAMHS-AASQLSPAAQQMQPTQTLQSPPPSGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQNEVTMLKNEVTQLKQLLLTHKNCPITTMQKESQGYLSPESSPAGSPTPVT-QQQVIQHNTITTSSTA------------PNHCTDINPIH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IL04-1", "uniprot_id": "A0A0R4IL04_DANRE", "id": "A0A0R4IL04-1", "name": "Cyclic AMP-responsive element-binding protein 5", "aln": "------MMNVDQDRPFVCIAPGCSQSFQREDHLIIHRHKHEMTLKFPSIKCDSMLSDQTPTPTRFLRDCEEVGLFTDL------ELNQSQTEEQTKPNFSAQT--------SAQRQPHTETQPEQGQ---HQQFQPQQQQSCALAHLNQNQLQTHSSQCQSQCTATYSSSNKQSAPSCLHSRQTNTVKSN-----MNMESQMSMNSSIIGIPGPAHSGSCSSVQ----------RSKVIPAHSQPAVSNGSQNPLCHMMEMMPSQ--PHPLSHLQSASHHHAS-YQQHCHSQSPQRLAHQHQSQDQSHHSHAHHSTPSHLPLGPSH--QNAP-PLSHQPIPIQMSSTPKQSHCPQ--SPPQPATGRRRRTAEDDPDERRRKFLERNRAAATRCRQKRKVWVSSLERKAEELTHTNLQLQNEVTSLRTEVTQLKQILLTHKDCPVSVRQRETQSGIG---SPTGSPVHSH----AIQHNSISTSSTLPR-------GHLTTHSHSTSNTQL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . . .. . ::*. *:.: . .:.. . * ** ***:.*.::*: ** ...*:* : * *. :* .::**. ..: ****** *: *::* .*:* : :.: :: . : :. : :.* ** : . *:* *.:* * *:*.:.:* : .* ..* *: *****..::**************************** ***:******:**:******: *:.**:****:*****:**::. *:*:*. :. **..**. .****:*:***: ..* . . ", "identical_positions": 124, "similar_positions": 105, "identity": "24.31%" }, { "cls_id": "homologset.agr.MGI:2443977", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70552-1", "uniprot_id": "GFRP_RAT", "id": "P70552-1", "name": "GTP cyclohydrolase 1 feedback regulatory protein", "aln": "MPYLLISTQIRMEVGPTMVGDEHSDPELMQQLGASKRRVLGNNFYEYYVNDPPRIVLDKLECRGFRVLSMTGVGQTLVWCLHKE-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P99025-1", "uniprot_id": "GFRP_MOUSE", "id": "P99025-1", "name": "GTP cyclohydrolase 1 feedback regulatory protein", "aln": "MPYLLISTQIRMEVGPTMVGDEHSDPELMQHLGASKRSVLGNNFYEYYVNDPPRIVLDKLECKGFRVLSMTGVGQTLVWCLHKE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30047-1", "uniprot_id": "GFRP_HUMAN", "id": "P30047-1", "name": "GTP cyclohydrolase 1 feedback regulatory protein", "aln": "MPYLLISTQIRMEVGPTMVGDEQSDPELMQHLGASKRRALGNNFYEYYVDDPPRIVLDKLERRGFRVLSMTGVGQTLVWCLHKE-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBT6-1", "uniprot_id": "GFRP_DANRE", "id": "Q6PBT6-1", "name": "GTP cyclohydrolase 1 feedback regulatory protein", "aln": "MPYILISTQIRLETGPTMVGDEYSDPSIMNYLGARKITVLGNNFSEYHVDEPPRLVLDKLDKIGYRVVSMTGVGQTLVWCLHKESSNTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:*******:*.******** ***.:*: *** * .***** **:*::***:*****: *:**:**************** ", "identical_positions": 62, "similar_positions": 14, "identity": "69.66%" }, { "cls_id": "homologset.agr.MGI:2443978", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJY6-1", "uniprot_id": "NAGA_RAT", "id": "Q5BJY6-1", "name": "N-acetylglucosamine-6-phosphate deacetylase", "aln": "----MRSGQSAALAP----------VLQFTNCRILRGGTLLREDLWVRGGRILDPEKLFFEERRVADEQRDCGGRILAPGFIDVQINGGFGVDFSRATEDVGSGVALVARRLLSHGVTSFCPTLVTSPPEVYHKVLPQIPVKSGGPHGAGVLGVHLEGPFISREKRGAHPEAYLRSFGANAFHDVLATYGPLDNVCIVTLAPELDRSHEVIQALTAKGIRVSLGHSVADLRAAEVAVQSGATFITHLFNAMLPFHHRDPGIVGLLTSDQLPPGHCIFYGMIADGIHTNPAALRIAHRAHPQGLVLVTDAVPALGLGNGRHTLGQQEVEVDGLIAYIAGTKTLSGSIAPMDVCIRHFLQATGCSVESALEAASLHPAQLLGLEKTKGSLDFGADADFVVLDDTLHVQATYISGELVWQAEEAGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZV7-1", "uniprot_id": "NAGA_MOUSE", "id": "Q8JZV7-1", "name": "N-acetylglucosamine-6-phosphate deacetylase", "aln": "----MRSGQCAAGAP----------VLQFTNCRILRGGTLLREDLWVRGGRILDPEKLFFEERRVADEQRDCGGRILAPGFIDVQINGGFGVDFSKATEDVGSGVALVARRLLSHGVTSFCPTLVTSPPEVYHKVLPQIPVKSGGPHGAGVLGVHLEGPFISREKRGAHPEAYLRSFEANAFHDVLATYGPLDNVCIVTLAPELDRSHEVIQALTAQGIRVSLGHSVADLRAAEVAVQSGATFITHLFNAMLPFHHRDPGIVGLLTSDQLPPGHCIFYGMIADGIHTNPAALRIAHRAHPQGLVLVTDAVPALGLGNGRHTLGQQEVEVDGLIAYIAGTKTLGGSIAPMDVCVRHFLQATGCSVESALEAASLHPAQMLGLEKTKGSLDFGADADFVVLDDTLHVQATYISGELVWQAEEAGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y303-1", "uniprot_id": "NAGA_HUMAN", "id": "Q9Y303-1", "name": "N-acetylglucosamine-6-phosphate deacetylase", "aln": "----MRGEQGAAGAR----------VLQFTNCRILRGGKLLREDLWVRGGRILDPEKLFFEERRVADERRDCGGRILAPGFIDVQINGGFGVDFSQATEDVGSGVALVARRILSHGVTSFCPTLVTSPPEVYHKVVPQIPVKSGGPHGAGVLGLHLEGPFISREKRGAHPEAHLRSFEADAFQDLLATYGPLDNVRIVTLAPELGRSHEVIRALTARGICVSLGHSVADLRAAEDAVWSGATFITHLFNAMLPFHHRDPGIVGLLTSDRLPAGRCIFYGMIADGTHTNPAALRIAHRAHPQGLVLVTDAIPALGLGNGRHTLGQQEVEVDGLTAYVAGTKTLSGSIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGLEKSKGTLDFGADADFVVLDDSLHVQATYISGELVWQADAARQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0U0-1", "uniprot_id": "NAGA_DANRE", "id": "Q6P0U0-1", "name": "N-acetylglucosamine-6-phosphate deacetylase", "aln": "----MPSNKSVSDAP----------ITQFVNCRILKNHKLQWEDLWVREGKILNPEKLFFDEQGFADHRVDCENKIIAPGFIDVQLNGGYGIDFSQASSDIRGGVALVAKKILEHGVTSFCPTLVTSPPHIYHKVIPELRVQDGGPEGAGVLGIHLEGPFISEEKRGAHPPKFLRTFQSGGVADLMETYGQLENVAMVTLAPELTNSAAAIHELSSRGITVSVGHSMADLSQAEEAVQNGATFITHLFNAMLPFHHRDPGIVGLLTSDRIPPGRTVYYGMIADGIHTHPAALRIAHRAHPAGLVLVTDAVTAMGLPPGRHTLGQQQIDIQGLHAYVAGTTTLSGSIATMDMCVRHFREASGCTVEAALEAASLHPAQLLGISHRKGTLEFGADADFIVLDDMLTVRETYIAGQQVWRK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR81-1", "uniprot_id": "NAGA_DROME", "id": "Q9VR81-1", "name": "N-acetylglucosamine-6-phosphate deacetylase", "aln": "MDVRIKCNSEEPESPEQKILASSQRLLQFTNCRLVRDHRIIHDDLWVRDGRIVNPEPVFFDERTKAHCRIDCGGAIIAPGYIDLQINGGYGVDFSYDTETIEEGVATVARGLVKSGVTSFCPTLVTSPSDSYHTILPRIPAEV--PKGAGILGIHAEGPFINPQKKGAHPEHCIQTIDKG-LSTLKETYGSLERIKIITLAPEKVTDPEVIGQLVERGITVALGHSMASLSDGERAVQQGATLITHLFNAMLPFHHRDPGLVGLLASDAVPHGRTVYFGIISDGVHTHPAALRIAYRTHPQGLILVTDAISALGLEEGVHHIGQLPLQVKQGKAFIAGTETLCGSIAPMDECVRIFQKATDCSVVYAIEAATLHPAQCLKIEKQKGTLDFGSDADFVLLDDQLRVLSTWIAGVCVHRTVK---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : **.***:::. : :***** *:*::** :**:*: *. : ** . *:***:**:*:***:*:*** :. : *** **: ::. *************.. **.::*.: .: *.***:**:* *****. :*:**** :::: . . : *** *:.: ::***** . .* * :** *::***:*.* .* ** .***:*****************:****:** :* *: :::*:*:** **:*******:*:** **:*****:.*:** * * :** :::. *::*** ** ****.** *:* * :*:.*:: *:***:***** * :.: **:*:**:****::*** * * *:*:* * : ", "identical_positions": 197, "similar_positions": 114, "identity": "46.57%" }, { "cls_id": "homologset.agr.MGI:2443988", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AWH2-1", "uniprot_id": "A0A8I6AWH2_RAT", "id": "A0A8I6AWH2-1", "name": "", "aln": "MEPPLIYVMLLLLGAFEFSSGVVHNKGKERTFFSCSGDGIYTGLHAIKLFLTTDNLKVYCFFKNENQSPSQKILGLFTSGGLAPNMIIMNSTYYGTYHFKLSPFTDRLQWIIDIPREKITVNTDIAAVEQWIIKFTMHEGLNIYDTEGTLLDLVREPILQWNLGTEFIQNSITHLYAFVDGIKVTRSPCANDVALIGLIMKPLLNGVFIGRTASGFWTYEECKWYDMTKLIYEGLKYEHQILTVIDLVLTNHFLVILTSLGLYVSGDLRYPTTSQIKLSRIEFCGFERVDYIKGNLWYNEKCFANREHFEVDYVTITFKRNRTLSESSSCFFSKEPFLHWLPCLYENYQNERDVPHVITFLIDQETESGVYLMHIQSSRETYVTVSMLKDGSPSAHPKFPSFKFPSTFTHPVGMVFHPRSHFLYVYGDKVWISMDGGNTFEILCNLVLNYVQETAHSFYTSDIAFILNDGKILMTKAGLNRYNELGMLNDTIFTLYYDHLGYIHKLTPRSFDYGTNLLGHGNSVSIFGKAPDMGFETAIVPQYISAKEMVFFAYVPLKTSKDLAQTMNFKNIHTGKTIEYSKSGIAYIRNVFSHD-DPKGFYTSVHTELIEPFGMEDSKESPCLHHPLEIKYSGNIFFTLTLTSQNIQEGFLSTDVEKTVLIPGHSSFMITEVENMQTAKALATMPQTVKSTLNFPLGSWFLYNFGSIRGRNWTIGTKPCNYWIQQDSLDFMSLNLVKYIDVGNTLNFQFKIIPTAKGMSTYPIPPVSVMIGNPSLLDVKAQGFFDLFFNYYLNIHVSGKFFLKGSTTLALIFWEGSVSCLVISLLPTIKSSCSYLRTMQHRPGRNIPPEDWISGVHKDSHGFNMIKTLPINYRPPSKMGISIPLTDNFYHADPSKPIPRNRFHKSKETGKYKQCANVTSREMCNCSQHQKTSHAVAFSDCKEKVHRFKFPVTQYPVALEIFNERDKISAEPPYLVTMTEVNMRENWQLKHNVPENVKKMKNYLEPLLKTPVYNPLGLNLSIKGSELFHFRVSVVPGVSFCDLHEEFQIYVDEVPLPFPGHALIAVSTSVVLGGLIFMAFVFQLRNIHPLRALKRSIMGNPVQTSTTTVNS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2RTF1-1", "uniprot_id": "CTSRB_MOUSE", "id": "A2RTF1-1", "name": "Cation channel sperm-associated auxiliary subunit beta", "aln": "MESPLIYVMLVLLNVFVFSSGVIHNKGKERTYFSCSGEGILTGLHTIKLFLTMDNLKVRCFFRNENQSPSKEILGLFTSGGLAPNMIITNSTFYGGYYFKLTPFSNRLEWLIDIPRQNITVNTDIAAVEQWMIKITMHEGLNIYDTEGTLLDLVREPILQWNLGRVLTEMEVRDLYPEVNDIKVTKSPCANDVALIGFMMKPSSNGVFIGKTISGFWTYKECIWHDLTEIIYAELKDEHQGLTVIDLVLTNHFLVILTSLGLYVSSDLRYPTTSQIKLSRAEFCGFERVDYIRGNLWYNEKCFANRESFEVDYVTITFNRNRTLSESSSCFFSKEPFLHWLPCVFSTIKNEKSIPRVITFLIDQETDSGIYLFNVQDTKETYVTVAMLKDGKPSPRPKFPSFHFPSTFTLPLGMIFHPRSHFLYVYGSQIWVSMDGGNTFEMLCNLFSHHVTKTSNSFYTSDIVFIVEDGRILTTKAGLTTYSELGILKDAIFTLYYDQLGYIHKLTPENFDAGSKLLGHGNSGSIFGKRPDLGFEAILVPQYISTNEMYFFAHVPLTMPTNIQWKKRFKTIHLGKTIEFSKTGLANIKNVYMHKTEPVGFQTSIHTEIIVPFGIENSKDSPCLLSDLEITYSGKLYYTIKLLSKNPLHELKSTDVEKSVLIPGYSSFLIMNITDKWTASALATMPQAIKSNLKFLTGSWFLYNFGTAGGRKWSISTRQCNYWIQQDSLDFMSLNLVKYIDVGNTIDFQFKIIP--KAMSTFPIPPVSMVVGNPGLVEVKTQGVFDLNENYYLDIHVSGRFFQKGSTSIALVLWEGSSKCYAITLLPTIKSSCSYLRTMHHTPGRHIPPEDWISGVHKDSQGFNMIKTLPINYRPPSHMGISIPLTDNFYHADPSKPIPRNQFHKSKETGKYKQCANVTSRAMCNCSEHQKFSHAVAFSDCKEKVHRFKFPVTQYPVVLEIFNERDKISAEPPYLVTMTEVNMRKNWQLKHNEPENVKKMKHYLEPLLKTPVYNPLGLNLTIQGSELFHFKVSVVPGVSFCELSEEFQIYVDEVPLPFPGHALIAVATSVVLGVLIFIAFVFQLRNIHPLKALKKSIRGNPGLTSSTTVSS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7T0-1", "uniprot_id": "CTSRB_HUMAN", "id": "Q9H7T0-1", "name": "Cation channel sperm-associated auxiliary subunit beta", "aln": "MESPLIYVSVLLLNIFEFSSGIVYNKDDTEKRFACSNKGFPQENEIIKLYLFLENLKIQCFFQTENEIASKAMLSVFTSGGLAPSLGIMNSTYNGIFHFNLTLFSDRILWLVDIPRENITQSTDIAAVEEWLVRITLHHGLNIYATEGTLLDVIREPILQWTPGDVIPESEISKLYPHVVDLKVTKCPCANDVALLGFIVDTIVDGVYIGITFGGFWHDYDTTWFNMTQTIYSQLQEEYEDLSLVDMVLTNHFLVILTSLGLFVSEDLRYPSRHSLSFSRADFCGFERVDYVKGKLWYNERCFANREHFEVDYVTVTFERNRTLSESSSCFYSQEPFLEWVPCLPHIFKGIKIFPTVLTFLVDQERGTGVYLFYNKVRKTAIASVSTLRNNEPNSQSKFPIFRFPSSFSSPVGMVFHPRSHFLYAYGNQIWLSVDGGNTFQLIANFHDDIIKKTFHSFYTSAITFVSQRGKVYSTKAGMGRYSAVGSVTERIFTLYYDHLGFLHKLTLGRFEASGPPTAFGNSRNLFGQPPDMGFETALAPQHTSLDEIIFFAYVPENEPQETIYSKKFGNIHYGKVIHSGKTGRAYIRKVLQHT-TPKGFLSSVIAEMKEPFGLEEVNESSCLSSSLLINKAGNVY-KLTLDSQVVQALFEDTDIEKTVVLPGYSSFLITSILDNKNALAIATMPESAPNNMTFLKSTWFLYNFGQRNGRTWKIYSKPCNYWFQHD--DSPSLNIVKYIDLGNSYVLKAKVIRNAKGFRMLEIPLLTVFVGNPNLLEVTAEVTFDDTDSYVITISAASKVLHQGSTSLAFIMWSASTECFVTTMVPTLKSSCSYLRSMHHIPSKFIPFEDWISGVHKDSQGFNLIKTLPINYRPPSNMGIAIPLTDNFYHADPSKPIPRNMFHMSKKTGKFKQCANVSTREECNCTKDQKFSHAVAFSDCREKVPRFKFPITQYPVSLEIINEDGRVPLQSPYLVTVTEVNMRHNWKLKHTVPENIKRMKQLVEPILGAAVYNPSGLNLSIKGSELFHFRVTVISGVTFCNLIEEFQIYVDEAPLPFPGHTLIAVATAVVLGGLIFIAFMFQLQGIHPWRTFQRWIRRNQEKFSSISLSELIHRSKSEE", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.***** ::**. * ****:::**.. .. *:**..*: . ***:* :***: ***:.**: .*: :*.:********.: * ***: * ::*:*: *::*: *::****::** .*******:*::::*:*.***** *******::*******. * : : .: .**. * .:***:.********:*:::.. :**:** * .*** : *.::*: ** *: *:: *:::*:***************:** *****: .:.:** :*********::*:*****:****** *******:**:************:*:****.*:**: :. : .* *:***:*** :*:**: : : : .:*: *::..*..:.*** *:***:*: *:**:*********.**.::*:*:******:::.*: . : :* :***** *.*: : *:: ****: *. :* :.: *******:**::**** *: . ..*** .:**: **:***: :.**: * .*: ***:** . . : . .* .** **.*. .*:* * *::* * * ** :*: :*: ***:*: ::*.** * *. :*::: .:.* *: : .**:**:*::**:***:* .: : .* *:****:: ..:.* .:******* **.*.* :: ****:*:* * ***:*****:**: :: *:* *.: ** :::.:***.*::*.:: ** .* : * .:.:.: :***::*:::*..* .* . :::**:********:*:* *.: ** ***********:***:************:***:******************* ** **:***:******::* ***::.** *********:*** *****:***** ***:** .::. :.*****:******.**:***. ***:*:**: :**:* :.**** ****:*:*******:*:*:.**:**:* *********.*******:****:*:**** ***:**:***:.*** ::::: * * *: ::.. ", "identical_positions": 578, "similar_positions": 332, "identity": "51.61%" }, { "cls_id": "homologset.agr.MGI:2443990", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUZ4-1", "uniprot_id": "D3ZUZ4_RAT", "id": "D3ZUZ4-1", "name": "", "aln": "MKLKQRVVV--LAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELVP--------------KLDHTLQSP--------WEIAAQWVVPREVYPEETPELGAVMHAMATKKIIKADVGYKGTQLKALLTLEGGQKVVFKPKRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEVKPVATEQLLSTFLTVGN-----NTCFYGKCYYCRETEPACADG-DMMEGSITLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPIAPVLSDPHLDTVDQRLLNVLATIKQCTDQFGMDTVLVEDRMPLSHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCS3-1", "uniprot_id": "XYLK_MOUSE", "id": "Q8VCS3-1", "name": "Glycosaminoglycan xylosylkinase", "aln": "MKLKQRVVL--LAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELVP--------------KLDHTLQSP--------WEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEVKPVATEQLLSTFLTVGN-----NTCFYGKCYYCRETEPACADG-DMMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDTVDQRLLNVLATIKQCTDQFGTDTVLVEDRMPLSHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75063-1", "uniprot_id": "XYLK_HUMAN", "id": "O75063-1", "name": "Glycosaminoglycan xylosylkinase", "aln": "MKLKQRVVL--LAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELAP--------------KLDHTLQSP--------WEIAAQWVVPREVYPEETPELGAVMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYSRDHVVEGEPYAGYDRHNAEVAAFHLDRILGFHRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGN-----NTCFYGKCYYCRETEPACADG-DIMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDAVDQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RH51-1", "uniprot_id": "XYLK_DANRE", "id": "Q5RH51-1", "name": "Glycosaminoglycan xylosylkinase", "aln": "MKLKQRVVV--LCAVLFLLGLAKVFLLDGGEGSAASRRDLRAFRKMEASLSLAKGA--------------RLTHTLQSP--------WEVAAQWVGPREVYPDETPELAAVLNALATAHVERADVGYKGTQLKALLVLDGGQKVVFKPKRYVRDYVVEGEPYAGYDRHNAEIAAFHLDRILGFRRAPLVVGRFMNLRTEIKPVATDQLLSTFLMHGN-----NTCFYGKCYYCRETEPACAEG-DVMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCEAVKKMPPYDAGPRLLDVIDTSIFDYLIGNADRHHYESFQDDGGASMLILLDNAKSFGNPSLDERSILAPLYQCCMVRVSTWNRLNLLKGGVLSSAMRQATAHDPAFPVLTGAHLTALDRRLNGVLATVRQCMETQGSENTLIEDRMNLPHP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95T10-1", "uniprot_id": "XYLK_DROME", "id": "Q95T10-1", "name": "Glycosaminoglycan xylosylkinase homolog", "aln": "MNKRSVIIAGIVASLLGLALGANFYFMYYLSAEEGHLASVRALENMIRHKMRHLKPNYLNRNPRFFMFRNKLLKNYKAAPYENASVLWDIANWWPHENEVYPLYDSSMGQLLETLRREPITRVSNLGRGTQLKLLVRLSHQQKVIFKPQWYPREEVIDGMIYSGKDRHTAEVYAFYLGAVLDFRWTPIVVGRVVNLKKEIYAKGDPELQQTINIETDEDGREKYCLFGKCHYCNEEETVCGDERHNIEGVLIYIVPG--TLAKRRSPWQRTYKDDKRAPWEDDMTYCKSLKNKMET---IRLLDLIDASIFDYLIQNGDRHHYETREER-----VVLIDNGKAFGNPNKDHLDILAPLYQCCLLRKSTWDRLQVFSGGVLTEIIDRLSKQDALYPLITDKHKKGVERRLLVVYAVVEHCMDIEG-------DKMFKTL-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :. :: :. :* : ::.::: . . . . **:..* . :* :. ::. *::* * .**** ..:. ::.:: : :.. :***** *: *. ***:***: * *: *::* *:* ***.**: **:*. :*.*: :*:**** :**:.*: . . :* .*: : : *::***:**.* *..*.: . :** : :*. .* *:* ** ***::.* * ** * :**.::*: ****:**:::***** *.******: :: ::*:**.*:****. *. .*********::* ***:**: :..***.. : :*. *:::. * :::** * *.:.:* : * *:* . ", "identical_positions": 136, "similar_positions": 139, "identity": "30.98%" }, { "cls_id": "homologset.agr.MGI:2443999", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q4S1-1", "uniprot_id": "PDE8B_MOUSE", "id": "E9Q4S1-1", "name": "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B", "aln": "MGCAPS-------------------------------IHVSQS--------GVIYCRDSDESNSPRQTSSVSQGPTAPLHG------LFVQTDAADAMPPSRAAGPPGAVRVRRSRAELGSGSSTGSSGPATTTCRGRRRHCCSSAEAETQTSYTSVK--------------------VLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLD-----KHHEIIVIDHRQSRNFDAEAVCRSIRATNPSEHTVILAVVSQASDDHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDSNKQIHRIHRD---SGDNSQTEPHSFRHKSRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRTTELYSPQLGTK-DEDPHTSDLVGGLMTDG---LRRLSGNEYVFTKNVHH--SHSHLSMPITINDVPPSIAQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCTETTLRAWLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGS--LDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPLAAESE------GSDCECNPTGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMP-VFDRNTCSIPKSQISFIDYFITDMFDAW-DAFAHLPALMQHLADNYKHWKTLDDLKCKTLRLPSDS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZTX5-1", "uniprot_id": "A0A8I5ZTX5_RAT", "id": "A0A8I5ZTX5-1", "name": "Phosphodiesterase", "aln": "MGCAPS-------------------------------IHVSQS--------GVIYCRDSDESNSPRQTSSVSQGPTAPLHG------LFVQTDAADAMPPSRAAGPPGAVRVRRSRAELGSGSSTGSSGPAATTCRGRRRHCCSSAEAETQTSYTSVKQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLD-----KHHEIIVIDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASDDHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDSSKQIHRIHRD---SGDNSQTEPHSFRHKSRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRTTELYSPQLGTK-DEDPHTSDLVGGLMTDG---LRRLSGNEYVFTKNVHH--SHSHLSMPITINDVPPSIAQLLDNEESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCTETTLRAWLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGS--LDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPLAAESE------GSDCECNPTGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMP-VFDRNTCSIPKSQISFIDYFITDMFDAW-DAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSNS-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95263-1", "uniprot_id": "PDE8B_HUMAN", "id": "O95263-1", "name": "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B", "aln": "MGCAPS-------------------------------IHVSQS--------GVIYCRDSDESSSPRQTTSVSQGPAAPLPG------LFVQTDAADAIPPSRASGPPSVARVRRARTELGSGSSAGSAAPAATTSRGRRRHCCSSAEAETQTCYTSVKQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLD-----KHHEIIVIDHRQTQNFDAEAVCRSIRATNPSEHTVILAVVSRVSDDHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRD---SGDNSQTEPHSFRYKNRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRTTELYSPQLGTK-DEDPHTSDLVGGLMTDG---LRRLSGNEYVFTKNVHQ--SHSHLAMPITINDVPPCISQLLDNEESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGS--LDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIE------GSDCECNPAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMP-VFDRNTCSIPKSQISFIDYFITDMFDAW-DAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AWN1-1", "uniprot_id": "A0A8M3AWN1_DANRE", "id": "A0A8M3AWN1-1", "name": "Phosphodiesterase", "aln": "MGCAPS-------------------------------IHVSQS--------GVIYCRDSDESNSPHQTTTISQGTATTLHG------LFIKTDAADTIPSVIAY------QTRHTRTNSHRERRENSGGQMCT-------------EAETQTSCTSVK-VSGAEDRLGPMRLSHEPIQVLLVFAKEDSQSDAFWWACERAAFRCNIARTPESALECFLD-----KHHEIVIIDGRHPRYFEAEAICRMIRATKLSEHTVILAVMPQTPSDQEEPSVLPLLSAGFSRRYLENSSVSACYNELIQLEHGEVRAQFKLRACNAVFTALEQCQEAVEISSEDHVIQYVNPAFEKMMGYHRGELIGKELTELPRSDKNSADLLDTINTCIKKGKEWQGIYFSRRKSGDSIQQYVKITPVVGQGGKIRHFVSIKRPYS--DNHRQVHKLSKEEKCCGEHSQSECNSLRHKDRRKESVDVRSISSHSSDAPSLQNRRYSSMARIHSMTIEAPITKVINIINAAQESSPVTVAEALDRVLEILRTTELYSPQLASK-EDDPHTNDLVGGLMSDG---LRRLSGNEYIFSKSALQNMSQSQLGVPVPLNDIPPSIAELLNEEEQWEFNILELEAATHKRPLSYLGLKIFSAFGVCEFLNCSESTLRLWLQVIETNYHSSNSYHNSTHAADVLHATAYFLRKERVKAS--LDQLDEVAALLAATVHDVDHPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTVRDSKCNIFKNMERTQFRTLRQAIIDMVLATEMTRHFEHVNKFVNSINKPMSAIEETSSNSEGSDCEGQASIRNSPENRLLIKRMLIKCADVANPCRPLELCIEWAGRISEEYFAQTDEEKRQGLPVVMP-VFDRNTCSIPKSQISFIDYFITDMFDAW-DAFASLPGLMEHLAENYKYWKNLDEMKCKSLRPPPPP-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NNF2-1", "uniprot_id": "PDE8_DROME", "id": "Q6NNF2-1", "name": "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8", "aln": "MGCSPSTLPPAPSAGQTGERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTLQPPSDGNGSTAGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGSTGTSGTSSSGGNSRPGHRKSSLALALTPEDEPMDVYQRNL----MDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDD-VLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSD------LSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPG--GQMDFIATLPQP---------KEAPRGSLHSVRRCSFDVRSIASDG--------LRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSST---RTAAIVPAKMKSNP-IIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVF---------------GGEEPRDHNPQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMP-MFDRATCSIPKSQIGFIEYIIQDMMHAW-ESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTLFLIG--------------------------------------------IHEIEKSQTIVQNEHYFDRVIELQDLD----------------------SLMVALYKDRVSPFPNVHNFETGVSIVLYDPSKFQLSVRQLDVLFKRFFPSFNISAIDHTREENLQRLECVERENSICRNRIT----------------------------RINHWMYHHHDDTPDGINKNS------------YGTVNGNSVP----------------------------------------------------------TQACEANIYTLLLHLNDSKAQHLRKAS-----------VPRLIRNIEFMSFLSDPIEKISQEGSHYWNILS------------------------------------------------------TWDFCALSLS----TQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDNP-----VQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLSISKKKFDFISEAILATDMALHSQYEDRLMHENPMKQITLISLIIKAAD----ISNVTRTLSISARWAYLITLEFNDCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLSDNVKINKEYWMKHKKPQ---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*::: : *: . : . . * *. . .*: * . ..: : : :. : : : : ::. : : * . *: . ..: : . : : .: :.* : .. *.: :: :. :* :: . : :::. :. : * : :.. :::. *:* :.*. : * : *: :: :. : :. : .:*: *:. * :** ** **::** : . :: :** ***.*** .. :***. . :* ::: ::**..* : :* . : . .: : : ** * :: :: * : . .. * . . :. ** : *: : : :. : :. :. : :. * : : **:.** **: : ::.* : * : * : * . * . .. ", "identical_positions": 64, "similar_positions": 167, "identity": "6.63%" }, { "cls_id": "homologset.agr.MGI:2444008", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZVH2-1", "uniprot_id": "A0A8I5ZVH2_RAT", "id": "A0A8I5ZVH2-1", "name": "", "aln": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPPPPPPPPPPP-ASGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGGRRKQPPPPP-ASASSASGPGRGGRGGGGGRTGGGGG--HLARTTSARRAVNKVVYDDHESEDDDEEEDMVSEEDEEEEEDGDAEETQDSEDDEEDDMEEDDDDSDYPEEMED-DDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVVRNFGNVLRLSPFCFEDFCAALVSQEQCTLMAEMHVALLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHH-VLPYQEAEDYPYGPVESKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEVQKNKPYVRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKVWYYSTKVQLAELIDCLDKDYWEAELCRVLEDIREEMQQHMDVTEDLTNKARGSNKSFLAAANEEILDSLRIKRGEDIDCDQ--NPEDTEKDKNEGENDSSKGAEKSREESEDQSPDKDADGKVLEEEPGQGKPEEPTEVGDKGNSVPANLGDNTRNASSEET-PCEGRSPEGWLSETHDSS-TAEKKVASELPPDVPEDSHK-TCDSSNTSATTASSQPNLENCSSSSSSSELTSSQSDSAKAADDPDIGERDSHTPVSVQEEIG-DFRLDKSNGEVSESPGTGKGTSGSTRIITRLRNPESKLSQLKSQQ-VAAAAHEANKLFKEGKEVLVVNSQGEVSRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLESNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQ---EEEETMQQATWVKYTFPVRHQVWKQKGEEYRVTGYGGWSWISKTHVYRFLPKLPGNTNVNYRKPLEGVKNNMDENKDESDKRKSPRSPKKMKTECDSEKGEARDADSTAGATAGTMELSKLPEKEEHDVKELLDPDNDKPFKEEPMEIDDSVKTESHMNSEESAQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIRQFTLEEKQRLEKLKLESGVKGAGKPPTGAVKSSSEPPVSTKADEGHQGDLLRQEQRSTPSQAGTADLGLGASQSDPLVLGISPPSLSTGKPDPKGQVLDDVSIQSPGPACQGQNSVESDLDARISEATSKGLELSQTKTKVTDSLTDDSKPTSADEGSTLICKSKKPLPQDDCSTAVSSSSKSTLPAPVPKSPRDRDARAFPKAMDLDGRLGGDSEYNSTLENNSGTMYMRDSSEEDMVVQNSNDTTSKRFITPDQGMESTEPTKCQLVS-KSTENCDNRLQGKVTEANGKKLGQHQ-KPEERAVNRCADQVSLRHSADRKNSEARESEKRGQKANKFQINGKDSKAKGYLKGPGMKDVSDGKVMSGAVEPKVNNINKVIPGN-IKSLAGKESAVKPFVNGDIIMEEFSEQNTSETNSYSLSSSDAKGNHQDGLHTLPSTKDSASTQVIIPPAPCPDRNSLNQVEDMETE---GPEVKKVTPSPITTGEDSNLGKDVMDENGLPSSKDENVNGESQRKTVITEVTTMTSTVATESKTVIK-----VAKGDKQTVVSSTENCARSTVTTTTTTVTKLSTPSPDSDVDTVSVKEQSKTVVTTTVTDSLSTAGSTLVTSMTVSREYSTRDRVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPCFNYNAKPALDIWPYPSPRP-----TFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGSTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVVIESWVAEEELELWEIRAFAERVEKEKAQAVEQ--------------------------QTKKRLEQQKPAVIAASTTSPTNSTSSTVSPAQKVMVAPLSGSVTPGTKMVLATKVGSPATVTFQQNKNFHQTFATWVKQGQ----------------------------------------------------------SNSGVVQVQQKVLGIIPSTAGPSQQTFTSFQPRTATVTIRPNTSASAGTTTTSQVITGPQIRPGMTVIRAPLQQP-ALGKAVIRTPVTMQPGAPQQVVTQIIRGQPVSTAISASSTASSAPVQKGLTPGAAAGTLQPSAPHSPRPQQGQVKLTMAQLTQLTQG-HGGNQGLTVVIQGQGQTTGQLQLIPQGMTVLPGPGQQLMQAAMPNGTVQRFLFTPLSTPVTAVSSSS--SSSSTNATATGSGEQKQSKLSPQTQVQPATTLAPTQSSSVSPAEAQPQPAQPAAQPQPQPQPP--------AQPEVQTQPAASSHVPSETQPSQAQSSKPLVATQCQPQSSVQGQSPVRVQSPPLTRIRPSTPSQVTPGQQPQVQTTASQPIPIPPPTSLQAPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVPSPSRPQPQTQQPQPQVIAVPQLQQ-VQVLSQIQSQVVAQIQAQQ---GGAPQQIKLQLPVHVQQNS--AAQAQHAQSVLTVQAASVREQLQRVQQLRDQQQKKKQQ-IEMEREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILKKRALLDKELQMQVQEELKRD-LKMKREREMAQVVQANAAAGPTPSVPAPVPAPAPAPAAPPAPP-SPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDS--KSKKKKMISTTSKEAKKDTRLYCICKTPYDESKFYIGCDLCTNWYHGDCVGITEKEAKKMDVYICNDCKRAQEGSSEELYCICRTPYDESQFYIGCDRCQNWFHGRCVGILQSEAELIDEYVCPQCQSTEDA-MTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERIQKRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A654-1", "uniprot_id": "A2A654_MOUSE", "id": "A2A654-1", "name": "", "aln": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPPPPPPPPPPPPASGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGGRRKQPPPPPPASGSSASGPGRGGRGGGGGRTGGGGG--HLARTTPARRAVNKVVYDDHESDDDDEEEDMVSEEDEEEEEDGDAEETQDSEDEEEDDMEEDDDDSDYPEEMED-DDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVVRNFGNVLRLSPFCFEDFCAALVSQEQCTLMAEMHVALLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHH-VLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEVQKNKPYVRHEPIGYDRSRRKYWFLNRRLIIEEDTDNENEKKVWYYSTKVQLAELIDCLDKGYWEAELCRVLEDIREEMQQHMDVTEDLTNKARGSNKSFLAAANEEILDSLRIKRGEDIDCDQ--SPEDPEKDKHEGENNSSKDAEKSREEAEDPSADKDADSKGLEEEPGHGKPEEPTEVGDKGNSVPANLGDNTTNASPEETSPCDGRSPEGCLSETHDSSSMAEKKVASELPPDVPEDSNR-TCDSSNTSATTASSQPNLETCSSS----ELTSSQSDSAKAADDPEIGERDSHTPVSVHEEIG-DFRLEKSNGEVSESPGAGKGTSGSTRIITRLRNPESKLSQLKSQQ-VAAAAHEANKLFKEGKEVLVVNSQGEVSRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLESNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQ---EEEETMQQATWVKYTFPVKHQ----------VTGYGGWSWISKTHVYRFLPKLPGNTNVNYRKPLDGAKNNTDENKDESEKRKSPRSPKKMKTECDSEQGETRDADATAGAAAGAMELSKEPEKKDQDVKELLDSDNDKSFKEEPMEIDDTIKTESHVSSLESTEVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIRQFTLEEKQRLEKLKLESGVKGAGKPPMGALKSSSESPGSTKASEGHQGDSLRQEQSPSSSQASTVDLGLGGSQSDPLVLGISPPSLSTHKPDPKDQVLDDVSIQSPGPNCQRQNSVESDLDARISEPAGKGLELSQTKTEVTDSSSDDSKPTSADDVGILICKSRKLHSQDDSSTVVSSS-KSTLPASVPKSPRDRDARAFSKAVDFDGRLGGDSEYSSTLENSSDNMCIRDSAEEDMVVQNSSEATSKRFIAPEQGGESVESTKCQVVS-KSTENCEDKLQGKVTEANGKKLGQHPPKPEERAVNRCTDQVSLRHSVDRKNSEPRESEKKGQKANKFQINGKDSKAKGYLKGPGTKDGSDGKVVSSAVEPKVNNINKVIPGN-TKSLAGKESAAKPFINGDIIMEELSEQNTSETNSYSLSSSDAKGNHQDGLHTLPSTKESASTQVITPRAPCPDRNSLSQVEDMETE---SPEVKRVIPSPVRTGEGSNLSKGFMDDNGLPSSKDENVNGESQRKTVITEVTTMTSTVATESKTVIK-----VAKGDKQTVVSSTENCARSTVTTTTTTVTKLSTPSPDTGVDTISVKEQSKTVVTTTVTDSLTTAGSTLVTSMTVSKEYSTRDRVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRP-----TFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGSTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAAEQ--------------------------QTKKRLEQQKPAVIAASTTSPANNTSSTVSPAQKVMVAPLSGSVTPGTKMVLATKVGSPATVTFQQNKNFHQTFATWVKQGQ----------------------------------------------------------SNSGMVQVQQKVLGIIPSTTGPSQQTFTSFQPRTATVTIRPNTSASAGTTTTSQVITGPQIRPGMTVIRTPLQQP-ALGKAIIRTPVVVQPGTPQQVVTQIIRGQPVSTAISAPSTASSAPVQKGLTPGAAAGPLQPSAPHSPRPQQGQVKLTMAQLTQLTQG-HGGNQGLTVVIQGQGQTTGQLQLIPQGMTVLPGPGQQLMQAAMPNGTVQRFLFTPLSTSATAASSSSNSSSTTTNATAAGSGEQKQSKILPQTQVQPATTLAPTQSSSVSPAEAQPQPAQPAAQPQPQPQPP--------AQPEVQTQPAVSSHVPSETQPSQAQTSKPLVATQCQPQSSVQGQSPVRVQSPPLTRIRPSTPSQVTPGQQPQVQTTASQPIPIPPPTSLQAPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVLSPSCP-----QPQPQVIAVPQLQQ-VQVLSQIQSQVVAQIQAQQ---SGVPQQIKLQLPIQVQQNS--AAQT---QSVVTVQAASVQEQLQRVQQLRDQQQKKKQQ-IETEREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILRKRALLDKELQIQVQEELKRD-LKMKREREMAQAVQANAASVPTPSVPAPVPAPAPA--APPAPPRSPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDS--KSKKKKMISTTSKEAKKDTRLYCICKTPYDES----------------------------------------------------------KFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDA-MTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERIQKRYYEKLTEFVADMTKIFDNCRYYNPRDTPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12830-1", "uniprot_id": "BPTF_HUMAN", "id": "Q12830-1", "name": "Nucleosome-remodeling factor subunit BPTF", "aln": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPP------------TSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEE--EEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMED-DDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHH-VLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKG-DIDNVK--SPEETEKDKNETENDS-KDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGDKGNSVSANLGDNTTNATSEETSPSEGRSPVGCLSETPDSSNMAEKKVASELPQDVPEEPNK-TCESSNTSATTTSIQPNLENSNSS---SELNSSQSESAKAADDPENGERESHTPVSIQEEIVGDFKSEKSNGELSESPGAGKGASGSTRIITRLRNPDSKLSQLKSQQ-VAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQ---EEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSS-KSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQK-KLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIE---TSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIK-----VEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRP-----TFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQ--------------------------QAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQ----------------------------------------------------------SNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQS-TLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQG-HGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTT----TTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQ---SGVPQQIKLQLPIQIQQSS--AVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRD-LKIKKEKDLMQLAQATAVAAPCPPV-----TPAPP--APPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDES----------------------------------------------------------KFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDA-MTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQI5-1", "uniprot_id": "A0A8M3AQI5_DANRE", "id": "A0A8M3AQI5-1", "name": "", "aln": "MRGRRGRPPKAQLVQEPS--------------------------TGPVRGLRPRRSLKPKVKGGSDEDYVTPKRGTHHHSTRGRRK--------ARSTASR----GRGRGRGTARGRGR----------RSTASGVVYDDHESDEDDE--DAVSLR---SEEDEYIEEPLTDEEEEEEEEEAINDESDYLEELDELDEDDASYCTESSHG-----SNTVGRKRPRPRRPPSPILEQKEIPLLELPNSSEDLLLPNEQLLNALAIYEVLRSFCTVLRLSPFRFEDFCAALVGQEQCTLMAETHICLLKAILREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVVRSYCESDPEYHH-VLPDLEGEDYPFSPLESKIKVLQFLVDQFLTTNLAREELMSEGVIQYDDHCRVCHRLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEICVAHKVPGVTDCLTEFQKSRPYIRQEPIGFDRHQRKYWFLNRRVVVEEDGEDDS-KQIWYYSTKVQLGELLELLDKGFWENDLCSVLEEMREEIHAHMDITEELTNKARGNNKAYLTVANDVILDRLKTKQEAELEEVKRRAAEEAERAKLEPKTLSDEPASGDQMSSNDSCPQQDSSNGNARNE--QTSSDASVSAVPVGEVLSSSVPEIAASSSSTVQTKPDSQSPIG--NAVTSSSSGEEKGEGTDGVEELTGKSSEGACHGEGDSVLEAELAQTADENSCS-----SHFSISECLRGPDEPDLVDRSSQSSLNSQDDTG----DGKANGDSTKT--------ASSRMITRLRNPDSKLSQRKVMQDKDGSSQDGSRALKETP---PLSSFGTFKRDSSK--------SSGFFKLGQEGKFRVYHNQYSTNTLALNKHQHREDHDKRRHLSHKLCMTPAGEFKWNGSLYGSKALTVSTLRLTIIQLENNIPAPFLHPNWASHRSNWIKAVQMCSKAREFALALAILECAIKPVVMLPVWKDSLGHTRLHRMTSVEREEKEKVKKREKKL---EDEETMQQATWVKYTFPIKHQVWKQKGEEYRVTGYGGWSWVSKTHVHRFFTKLPGNTNVNYRKALEAAKTGMDNQAALPGAPKTVVKKDEMSSQNVPDKDNAQVLSLDSSEEKLSVEKDHVLKVEEQDEEKMNETTEEKCNEKN--ESVEEMDTSSPNSANEG-KVEITNAST----------DDSTMKEEPLDSEVVKDNTLNQPQ-----------QCFWHDVVNVSEGFLQRTAYKKLKPSKLDGLLERRVKQFTIEEKQ--------------------RIDKLKQAPTSKPLTETAVENKETTLAAQD----------------------HKVKIEGTISETPKARQTEGVACLAIQEKD---------------------------------------NVVKRLVFNQEDEQAKTNTSGQKNTLDVRLNDSVELAPKENQQKLAETDPKTAS--------------------RVAMSELNGNSQSLDQSLSLNAKPDKNITEATCPPEDSAGKDNIENSENDLDVKKTVPVQVNGKDVTVDPECKN--LTDNGDTKELTNTIVEDIKAISPKEPVKSLMNGDATQECLKEWTNSTIPQVNLDEEKAVTKLDPDYPPPQKVAKLENNIEKPIDSSVSLSVPEPSPVASEPNERSEVPSHSSKVEPMQVVEAKPSVPSPVPSAEESSLSSDLTE--------NSSSIGET---TVVTQVTTTTTTVSTESRMVLTSRDSLASKNGLNTAVLTDSKVESSSSVSTLSSTTTTTVTKVLSSSQEATLTTECKTMVMKTLTDTTSSPSGSTVKSMTVSHEYSTRDRVRLLKFSRTKKTRSGTALPSYRKFVTKSSKKSIFVLPNDELKKLARRGGIREVPIFNYNAKPALDIWPYPSPRP-----TFGITWRYRLQTVRSLAGVSLMLRLLWACLRWDDMSVKPSPTGGTTRTETSDTDITTTEIIKRRDVGPYGIRSEYCIRKIICPLGVPETPKETPTPQRKGLRSSALRPKKPEPAKQTGPVVIETWVAEEDLELWEIRAFTERVEREKAQAADPTKVSVQKKAEEVKAQLEAQLKQQRLAAQQKRLEQQKPSTTSN-TTTLTSTPTTPGTTTQKVVVGSISGQVTSTPKVVMTTKLGSP--VTFQQNKNFQQSFASWVKQGQQGNSVSTSSVVTVAASSATTSGQTFHIAAAPGSMAGSVIAAKLPVPANSKIVTVNVPTTQGGLVQVQQKVVGIIPSSTAGNAQSFPPFQPRTATINIRPNTT----TSTQQVLTTGTTLRPGMTVIRSPLQQATTLGKTIIRTPLMVQQGQTQQQVQTSSGTQVVGTPPRLP-----TPNQ----------PQTPQTPASPRPQQGQVKLTLAQLTQLTQGAQGGNQGLTVVIQGQGQTTGQLQVIPQGVTVIPGPGQQLMQAAMPNGQVQRFLFTPMAPAPTPAPAPVS---------------------APAAPSNTTPSSVPPAAAPTAVTSTTPAPIQTAARLAPQPQPP-----------------------PSLPPPPSVPPSQPVQHTPAPIQTAVIPQP-----TPP---IQPHPPVQLRPQPQLPPQNPVVPPTPVSTPQIAQVTATAPPQQITTLPVTQTTVTKVQPQIQLP---------------PQLLSVPGLQQ--QVLSHIQSQVAAQIQAQVGTTAGMPQQIKLQLPIQIQQQGGGQVQAHQIQNLVTIQTASVQEQLQRIQQLCEQQQQKKKQ-QEAKREQAQQHVSQSDLIQKQVAQKQNVAIEQLKQKKTMTPAEREENQRMIVCNQVMKFILDKIDKDERQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKADILKKRALLDKELQLQVQEELKRDLIKLRREKEKAQAAAAQAAAA-------------------AAAAAAASTHVHSGLSSYTGTVTSPTSTHKRKREEERDAA-KPKRKKMISTTSKDSKRDIKLYCICKTPYDESKFYIGCDLCSNWYHGECVGITEKEAKKMDDYICSECKRAQEGNTEELYCICRTPYDESQFYIGCDRCQNWYHGRCVGILQSEATHIDEYVCPQCQSTEDA-MTVLTPLTDKDYEGLKRILRSLQSHKMAWPFLEPVDPNDAPDYYGIIKEPMDLSTMEERIQKRFYSKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEFLESFFVQKLKAFKASRSHNNKLQSSAS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0T1-1", "uniprot_id": "NU301_DROME", "id": "Q9W0T1-1", "name": "Nucleosome-remodeling factor subunit NURF301", "aln": "MSGRGSRKRGRPPKTPNER-------------------------ASGRFNYQLLKKPKYLSEGKSQPSTPSASRGISPQSD-------------EGSRSSHNNHTNRSRGSAAKRGRGR--------------KSAVQPNTSS---------------YSGRKGYESEYHYGSDFGDSEEDKSDNEDDMLLTPSDDESLEVANESESEFSVCSFNQNGVGRPPRPPSPEPVWLQEGRQYAALDLPDSSEDLFIANTHVLRALSIYEVLRRFRHMVRLSPFRFEDLCAALACEEQSALLTEVHIMLLKAILREEDAQGTHFGPLDQKDTVNISLYLIDSITWPEVLRSYVESDKTFDRNVFHILSHTEYPYTGIDNRLEVLQFLSDQFLTSNSIRDVMLQEGPIHYDDHCRVCHRLGDLLCCETCPAVYHLECVDPPMNDVPTEDWQCGLCRSHKVSGVVDCVLPQEKQGVLIRHDSLGVDRHGRKYWFIARRIFIE----DQENFTCWYYSTTSKLKLLLSRLDAEELETRLHSQITERRDEIERQMKLTETLTNEHKHTKRSVIEIEQEAKNELLEKEVLDEDEKDG--------------------DAKSESQSIEGTKKQEE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------CKMVTRQKSNQLTNG-------------------------------------------------TLHFKLGMEQGFKNYVNQYSTNPIALNKPQRNEERDKRRHLSHKFSLTTASDFKWIGITMGTTDNMITTLRQTLINFESNIAASFLNINWVVNKKIWNAAVMNARRPSEFAVVLLLFQASLKSVVFANVWHEQLGHTTLQRITSAEREERKKLEKREKRERDDEEERNRLAFNYIKYTLGLKHQVWKQKGEEYRVHGQWGWLWLSSSRRCGVRARRAQPLTHNRVYVHYTMGEENDVNEIILVDPRTQRFMQQCESSN-VDGQVCHYLPDQYKNVKVIEDVTEKIKGHIDVSKALNAPGRTYYSKVARKSRLDDLLDRRLKLAEVEEQMASKIPSDMKPLLVSSQNNTANSKQTFLEKRLLRLTEVQAKG---------GPANVNLELVNSLAKQIQTVRLQFSQLNRFAKVFRCYTKECNTNSNAVSQITQNTCYSPLCLQKARAKKELLLLLRKAHTAGNGSKETVAAILGAVK--------KPSILEQKLTEGKRESTQVAVDDSEEGKPAESEAPLDLLQDWEHARAHAVPFSDS----------------------LLTECILVDQECVTNTKIKQEVNASSGCNTTPDSNTQDSDKIDYIESMDVCSNVEIESTEDS-------------------IVTGLNSGNAEDVDMTPGWRRKRNQKSKKSYIGTKDVLDQTLDKDIPLNKQ-NRRFPITARPVKRECVKKYERETFENGNERVYSTSSPRGRVYLLN---------------DAAKLYEQAVKTEDKSTITKKPSYSRYPLISNFLTHKKKRSLLVLPRFELLKLARLGGKSSTNGFHHAAKNNTIWQYQ--CSRPLFRTCWSYRTSNATSLSSLALQLRILWSCLRWDDMIAKPPSTDGKHQVTTDTEIVTLELLKLRHS-----GRYGEKTSYLRRKVVIPLEMPKTVREVTSIRSGLRKRKRAESPQPTEPQITEEWVDEDKLELWEIKFMGEKQEKARLSAVTRSVASRQLEASGS-NGSNTSTNGALGVAGRVQLAPKLSEDVKEKMEQQLKLQRAVHQQRKLVATGEITRSVTPVKGQVIGSRRVIVKNPDGTTRIIQQAVTQVSRTGGANTAAAAASPTVGGSTSTQSNPSTSTPHKVQIIRGPDGKVSVRGLNPGQQLVQMPDGKLHVLTTTTSSNSAGQGNKMKVPIKPASTSSSPAISSAQTTTNPVTPVIKQIAVKHVTKNSATQSIASS------------------------SRVALPLAQIKNKLLLAQQQQQSTSSSPATSSSPVQKIVSKVVNTSTSGQTLQQVFVQSGSKLVVGQNAQGQKVIISTSAAQQ-----------------------------------------------------------QGTSPVQQQQLVQSQPIQQSPQQISMTQVGNQPTQKVIQQIVNTSNVQQQIVVGGQRIILSPGQTIVTQRNVPQ-SQALQMVQQQIQTQQQQQQHHVVQPQQQFVVQSNQIVQSS-----------------PSAQTKLVKQLVVQQQSQQTIEEKTQITTTDSNETGTQQVLVPN---STLAQQLAQGKLQVATVNGQQVIVKPLGNNQAQIVAHIKHQGDGNAHIVTSN--------------------------SATAVPQANPQTSPVKQQALPPQSPQQVVVQQQQIHQQ------------------SPTNFESGVTPITQQPVLTQAVQAPAQQQALSVEESLLQNQPPGTVIKCVTAQVLQTEHGPRIVLQGLVGNDFTAQQLQLVQTQVKQQLMKAQESNGKLGVLGPTKIYLAVQ-------------PENAVQSQPPPLTPVHQSAAHQQTNNIEIDADTLATTYEANSTIKDIAINNGDDQENSKCAETENSNITTNESFAGTSSLLEGSEHDEPTNLAGLDISETDLENKQNESFVVTRGYIQKS---ISNALKQGNLSPELEEK----LVCMQKQQENANSTNEWETCSRGSVNEEALTPSRQTDDTEWKIRTSLRRPNAMTTSSQFNRILKKNRSKNDEVAELGEQKQSQLERHKELLKKNILRKRSLLERNLQS-----------EIHEDVKTKVQRHVRPLSNASPDEQSENERSGEPNLDFKRTEVQNPRHGAGRPKKLTRKKEKLYCICRTPYDDTKFYVGCDLCSNWFHGDCVSITEEASKKLSEFICIDCKRAR--ETQQLYCSCRQPYDESQFYICCDKCQDWFHGRCVGILQSEAEFIDEYVCPECQRKNDANAANMKKLTSNDVEELKNLIKQMQLHKSAWPFMEPVDPKEAPDYYKVIKEPMDLKRMEIKLESNTYTKLSEFIGDMTKIFDNCRYYNPKESSFYKCAEALESYFVQKIKNFRENVFDQRT------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** .* . :. . : : . . : :.. . :* .*. * . * * . .* : .* . .. .* ..: :.: : :::.* .: :. :.: :**.. .. ** : * :: . *::*.*****::.* :::..::****:* * ::***** ***:****. :**.:*::* *: ****:*****:..* *** * **:** :**:**.:*****:* * *** :.: *: . :**: ::.:::***** *****:* *: ::.** *:*********:**********.********.**:::** ::*** :* :***.**.**: :*. :*::.:* ** *****: **:.:* ::. *****. :* *:. ** * * : : *:*:. :*.:** ***: : .::: : :: : :. : : : *. . . :. ::: :::** :. : . . . .**** * :: * ******.:**** *:.*::******:**:.:*.*.:*** * *:. ::*** *: ::*.**.:.**: **. :: * ** . :. ***:.* :::.::*.**: :*::.**** *:*:** ****::*::*:**: *:*.. .::***: ::** * * ** *:*.:: . .: . . * * : : .: . . : : : . : . . : : . : . : : . :: * . . * * .. :: :: . : . . :. : . : : : .. . . ..: : * .:: * . .. . . : : .. .*. * :* : . . : . : ..*.:. . : : .. .: : : :: . . . : : .: :. : :. .. : : :. . : . : . .: . . :. .: : : * : * . . .. .:. :*** * *: * : : . :* . .* .*. . : : . *. . : . . . *: : : ... : .*: .: : . . : *.:* :*: :: ::.. : : .: :* :* : : : *.: : . : .. : . . :*:::.* : ..:**: * : : : * * .. . *.:.: * .. * :* ....: .: .:: : : *. . .:.. :*: * * * :...:.. :.: : . ..:. : : . : * :.. ** : :: : : * :. **::: * . . ::. . :.: *: .. : ** *:: : . ::: : * *: : * : * * : *: : **:* . . *:: . :* *: : * . ***:: .: *. .* . . .. . . . ::.. * . * . * : * * . . * : : *. *: .. : . . . : * . . :. *: . * . * . :*: : . : . : ::: . . . .: : . . : : :::: .: : .. . : .:* :: : * *.: :: .::* .*: :** * : :. :: * : . :.* . .:::.:. *: : * : : :. :.: ::. : :* * ::. ::.:.:: : : . . . . :. : : : . : :: . ..* :::. :*****:****:: :*** **:**:*:************ *******:** .:** : :. **.:* * **.:::.:* ** ****:*****::***** :******* ** ::: . * **:**:.************** ::.**:*** ***:****:* *: . .:.. ", "identical_positions": 469, "similar_positions": 751, "identity": "14.43%" }, { "cls_id": "homologset.agr.MGI:2444022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BH93-1", "uniprot_id": "MISSL_MOUSE", "id": "Q8BH93-1", "name": "MAPK-interacting and spindle-stabilizing protein-like", "aln": "MSDEFSLADALPEQSSAKPPAVTNTKAGHSSQGWPGSSPWSNPSAPPAMPSGLPPSSAAPSTVPFGPVPTGMYPSMPPTGPPPGPPGPFPPPGPSCPPPGVPYPAPAVPGPGPTGPYATPNMPMPELPRPYGAPTDPAAAGSLGPWGPMSSGPWAPGIAGQHP--NMPYRSPGPYPTVPPPVS--GAPPVPWGTVPPGAWGPAAPYPGPAGSYPTPAPHPALNNPYQVPSGPAGAPPMPGGPHSYH--------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZNX9-1", "uniprot_id": "D3ZNX9_RAT", "id": "D3ZNX9-1", "name": "MAPK-interacting and spindle-stabilizing protein-like", "aln": "MSDEFSLADALPEQSSAKTPAVTNTKAGHSPQGWPGSSPWSNPSAPPAMPSGLPPSSAAPSTVPFGPVPTGMYPSMPPAGPPPGP---FPPSGPSCPPPGVPYPAPAVPGPGPTGPYATPNMPLPELPRPYGAPTDPAAAGTLGPWGSISSGPWAPGIAGQHP--NMPYRSPGPYPTVPPPVS--GAPPVPWGTVPPGAWGPPAPYPGPAGSYPTPGPHPTLNNPYQVPSGPAGAPPMPGGPHKVNEVPGGSLSDDSDQKSSPESTGQVKSSPESTGQVKLLKADDKPVRKRHPKRKRKPLTWGDIKNLTYQAETLGKQQGYNTNDPKMMLLCLITILHVNSQHDRSDPN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NDC0-1", "uniprot_id": "MISSL_HUMAN", "id": "Q8NDC0-1", "name": "MAPK-interacting and spindle-stabilizing protein-like", "aln": "MSDEFSLADALPEHSPAKTSAVSNTKPGQPPQGWPGSNPWNNPSAPSSVPSGLPP-SATPSTVPFGPAPTGMYPSVPPTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAPPMPGGPHSYH--------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************:*.**..**:***.*:..******.**.*****.::****** **:********.*******:**:****** ***.******** *****:**********.*****:*****************.*****.:********:.**:* **** ******: *** : .****************.****.*:******. :*: .**:******:**********. : ", "identical_positions": 189, "similar_positions": 42, "identity": "54.0%" }, { "cls_id": "homologset.agr.MGI:2444023", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HC1-1", "uniprot_id": "TDRD3_RAT", "id": "Q66HC1-1", "name": "Tudor domain-containing protein 3", "aln": "-----------------------------------------------------------------------------------------------MLRVQMTDGHTSCTAVEFSYISKISLNTPPGTKVKLSG-TVDIKNGFLLLSDSNTTVLGGEVEHLIDKWALQRSLLKHNRSN--IGAEGGPPPFLPFGQKCASTVQVDSRELDRRKTLQVSLPAKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGVRSH-----LNIGAGGHRNREVSQKEKASK----SESKNE-----------------GVYRELVDEKALKHITEMGFSKEASRQALMDNA-NNLEAALNVLLNSSKQ---KPVVG--PPPRG------RGKGRGRVRSEDEEDLGNARPSAPSTLFDFLESKMGTLNMEEPRSQPQHLYQGQHRVSNTEQNGIKDGNQSRH-LPRNDPRQPRNEKPPR------------FQRDTPNLKSALENSV--------------------LSRN---RGSERPSSSSGSDVWAEERIKCDRPYSRYDRTKDASYPLGFQHNDG-AFKRRDNSMQNRSGRGPLYAEAK-ENPHPSEFVDYNNQKRGKRENQTSNPDHFYDRKSRTMNSEAFSGLKIEKHFSANTDYQNPVQSNSFVGVPNGETDMPMKGRRVGPIKPAGPVTAVPYDDKIFYNSGPKRRSGPIKPEKVIESSIPVEY---------------AKMWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFTDYGNYEEVLLSNIK--------PVQTEAWEEEGTYDHTIEFRRGGDGQPRRSTRPTQQ--FYQPPRARN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W18-1", "uniprot_id": "TDRD3_MOUSE", "id": "Q91W18-1", "name": "Tudor domain-containing protein 3", "aln": "MAEVSGAALSQAGWYLSDEGVEACTSSPGKGSIN--DIILIALNTDLRTIGKKFLPSDINGGKVEKLEGPCVLQIQKVRNVAAPKDNEESQAAPRMLRVQMTDGHTSCTAVEFSYISKISLNTPPGTKVKLSG-TVDIKNGFLLLSDSNTTVLGGEVEHLIDKWALQRSLLKHNRSN--IGAEGGPPPFLPFGQKCASNVQVDSRELDRRKTLQVSLPAKPANDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSN-----LNIGAAGHRNREVLQKEKASK----SESKNE-----------------GVYRELVDEKALKHITEMGFSKEASRQALMDNA-NNLEAALNVLLNSSKQ---KPAVG--PPARG------RGKGRGRGRSEDEEDLGTARPSAPSTLFDFLESKMGTLNVEEPKSQPQHLHQGQHRGWNAEQNGMKDGTQSRH-LPRNDTRQPRNERPPR------------FQKDTPTSKSTVENSV--------------------LSRN---RGSERPSSSSGSDVWAEERIKCDRPYSRYDRTKDASHPLGLQHNDG-AFKKRENSMQNRPGRGPLYAEAK-ENPLPPEFVDYNNQRRGRRENQTGHPDHCYERKPRTMNSEAVSGLKIEKHFSVNTDYPRPVQSNS-LGVPNGETAPPLKGRRVGPIKSAGPVTAVPYDDKIFYNSGPKRRSGPIKPEKVIESSIPVEY---------------AKVWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFTDYGNYEEVLLSNIK--------PVQTEAWEEEGTYDHTIEFRRGGDGQPRRSTRPTQQ--FYQPPRARN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7E2-1", "uniprot_id": "TDRD3_HUMAN", "id": "Q9H7E2-1", "name": "Tudor domain-containing protein 3", "aln": "-----------------------------------------------------------------------------------------------MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSG-IVDIKNGFLLLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSN--IGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTMPVKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSN-----LNMNAAGNRNREVLQKEKSTK----SEGKHE-----------------GVYRELVDEKALKHITEMGFSKEASRQALMDNG-NNLEAALNVLLTSNKQ---KPVMG--PPLRG------RGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQYRSSNTEQNGVKDNNHLRH-PPRNDTRQPRNEKPPR------------FQRDSQNSKSVLEGSG--------------------LPRN---RGSERPSTSSVSEVWAEDRIKCDRPYSRYDRTKDTSYPLGSQHSDG-AFKKRDNSMQSRSGKGPSFAEAK-ENPLPQGSVDYNNQKRGKRESQTSIPDYFYDRKSQTINNEAFSGIKIEKHFNVNTDYQNPVRSNSFIGVPNGEVEMPLKGRRIGPIKPAGPVTAVPCDDKIFYNSGPKRRSGPIKPEKILESSIPMEY---------------AKMWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIK--------PIQTEAWEEEGTYDQTLEFRRGGDGQPRRSTRPTQQ--FYQPPRARN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NYG6-1", "uniprot_id": "TDRD3_DANRE", "id": "Q6NYG6-1", "name": "Tudor domain-containing protein 3", "aln": "MCDLS-SALIKEGWYLTDEGIEECKSSSEKEKTSPTDIIQVALNNDLRPIGKSFLPADINSGRIEKLEGPCVLQVQKIRNVAASKDHEESQAAPRMLRVQMTDGHTACTGLEFKQLSKISLNTPPGTKVKLLG-VVQVKNGILLLDDSKIAVLGGEVDHMIEKWEFQRSLAKHSRRN--IGAEGGPPPFVPFGQKCVHKEQVDSRALDQRKTLQSTNAVKSADDNDEFEKQRTAAIAEVAKSKETRTFGGGGN-AGGN-----LANPGSSYKSRDTYQRKREEREKPWTENKSD-----------------GVYRDLVDERALRDIMEMGFNREAARQALLDNN-NNLEVALNLLLTRANQPRAAPVEQSRPPPRG------KGRGKGRSRQDEDEEAG-GRPSGPSTLFDFLESKMGTFSIDDSKP-SQQDHQTKMNFSNSDQ-MSRDAGQFKP-PPRNDGRSQRNDRPPR------------FQKDGDFPKPTPASSS--------------------FSQPQKWRDGERTGRGGGPERWKNESQDARNAPVSYSSSFSKS-----REQQG-ASGKELNKEQDGTGPASFRKIQS-NGPAPP---KFSTPADPKMRNEPNNRRKGRPERPNSGYFEHSQDALGKKDFQDEGQFVK-VGPVSNTPLPNGD----LEHRRTGPIKPH--FSAPPPRQTNMHNPASKRRSGPIKGP---RDSVDINN---------------FVNWKAGDQCLALYWEDNKFYRARIDAVHPSGSTAVVVFSDYGNCEEVLLDSIK--------PLHMDD-DEDVYYENSLEFRRGGDGQPRRS-RPTQQ--YYQPPRARD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUH8-1", "uniprot_id": "Q9VUH8_DROME", "id": "Q9VUH8-1", "name": "Survival of motor neuron-related-splicing factor 30", "aln": "--MELGKKLREVGWYLTEEGLKIVTTAVGSEDVR--KIVNDALNRDLRDIGGGALPAKRED---ATLPGKIVLQVQRVRNIAAPKANEESKAAPRLLQLDLSDGQNSIKALELEPVPQLNLNVAPGSKIYFKAEKLQLMQGFLLLKSSEIQLLGGRVDALYEKWDLARTMMRYARSGRPLNGTSAPPPWVAFGRKIDSNAESEMN----FKSLGEGDKDKPAKENEEFNAMRTEAIAVATKAGGKKIFGGGGQNIIDHNVKKILDKGFSEEEARSALSATRNNLERALYNLKRRSEAGGVGPIESVGRPGRGDRPPREGKRGASAKDEVEAPKPAANTTLFDFLTNKLPAKETPAASNAETFAAAPTAAPTAPPTTNHFNPFKQYGSSRFSDSESKPSAMGGGGKFADRSRFENNVSSSFAAHRGGHVGSSRGGGRNRGGGRDERPPREERAYREDRPPREEKPPKEERPPRERGAFNDRAAGRYKPETPTVKTANRNGSDNVSLKPNSEIKPDHETTNGKDHTGNRRGSERGSNRGGSNRAENGNANGNRRNKPAASLTSASSAAKSTNSAGDDFNARLSKITEETANLKVSSAPKRENRRKQGGQANRLAGSGTETTQQQQPAQLHSQKPEKAQTNQKHHNPRHNSQANYSQLAN--GYTYDPSKIMGFQSKEANEFAMNLLKSQGVTLPNEKQQEEEQQESPPMSFGPVSAPVSRAQPAPVAVPQAAPRDQFGMVPGDAWMWQKGDLCMAKYWDDGRYYEAEITGVS--EKTCVVFFMGYGNHEEVLKVDILPITDAQNRPLSNSAQQQQPHLQQQQPHLQQQQHSRYRGDRQTQQQQVYVPPHKREH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:::::**: : ..:*:. :.::.**..**:*: : . ::: :*:***..*: :***.*: : :** : *:: :: * . :. ..***::.**:* : : . *:* *.:.:*:**: ** *** .:*: .: ***** .: * . . *.. . : : * * .::. *: : *:. :*:* *:* . . . : *. .* : * .* ..:.: . . . : * :. .:: . . : . . :: :: : * .: : ::::*** :: : *.. .. : *..** . . .: : . . . * .. * . .. . .. . :. .: .:... : .: : . * : . :*. . : : .. **:. .. : *: ** *:* **:*.::*.*.: .: *.** * .*** **** .* *: . ::: :: . : : . *. * *** * **: *: ", "identical_positions": 106, "similar_positions": 208, "identity": "12.46%" }, { "cls_id": "homologset.agr.MGI:2444024", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZP73-1", "uniprot_id": "D3ZP73_RAT", "id": "D3ZP73-1", "name": "", "aln": "MRLAQP-DMVSAATTEEARLSWPLAEGADKSPLRVLSTTESLLRLQRTQRVWQVPELDAEHAKAFLKPWPLGSFLVIGQDPDQVLMLKTGPSSGDINTYQIQKFPGGVSLESSNLCMPDFPHLLAFLSASRDVLPRTLLLPTPTVGPGDKHSDPRRLGCIQVDTSGRVLSVVNQLYLETHGGWET-ETPQQTKPETGQKRSLAPRMPTPHRVSWVEESLKPEAHHTGQEVHHPERQVHYPGPEAHSLGPEVHFPSPVLEEEEEVNNDSYKDE-EEGCEDMLTAHIRALASARSSYVARQYQCLRARLISDSGNPYSPGDPATELLQDVRQLLTDLQDYLAKDPDVRAVFGNRGPSIPR-EEDLGPAVEVALCRAVLEPLKPALWTKLRTLRAQELRRLRRRQIALRVGAGP--------EGQSPALRN--RIHARLAHLHAACAPRRKVALLLAVCSDVYAGLAGGENKEPLGADAFLPALTEELIWSPHIGETQLDVEFLMELLDPGELRGEAGYYLTTWFGALYHIAHYQPDAGRAPQELSSEARASLRQWHRRRTLHQQAQPTAPENQPFEEPWAIGDP------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UW3-1", "uniprot_id": "RINL_MOUSE", "id": "Q80UW3-1", "name": "Ras and Rab interactor-like protein", "aln": "MRLAQP-DMVSAAPTEVDRLVWPLADGADKSPLGVLSTTEPLLRLQRTQRVWEVPELDAQYAKAFLELWPLGSFLVIGHEPGQVLMLKAGPSSGDINTYQIQRFPGGVSLESSNLCMPDCPHLLAFLSASRDVLPRTLLLPTPTVGAGDNHSDPHRLGCIQVDTSGRVLSVVNQLYLETHGGWGT-ETPQQTEPETGQKYSLAPRKPTPHRVSWVEDPLRPEAHHTGQEVHHP-------GADAHSLGSEVHFSCPALEEEE-VNNDCYKDEDEEGCEDMLTAHIRALARTRSSYVARQYRCLRARLISDSGNPYSPGDPATELLQDVRQLLTDLQNYLAKDPDVRAVFGNRGPSILR-EEDLGPAVEVALCRAVLEPLKPALWTKLRTLRAQELRRLRRRQIALRVGAGP--------EGQSPALRNRNRIHARLAHLHAACAPRRKVALLLAVCSDVYAGLGGGENKEPLGADAFLPALTEELIWSPHIGETQLDVEFLMELLDPGELRGEAGYYLTTWFGALYHIAHYQPDTGRAPQGLSSEARASLRQWHRRRTLHQQAQPTAQANQPFEEPWAIGDP------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZS11-1", "uniprot_id": "RINL_HUMAN", "id": "Q6ZS11-1", "name": "Ras and Rab interactor-like protein", "aln": "--MAQPEDKAPEVPTEGVRLVPPQVNKADRTPLGVLSTLEPLTRLQRTWGVWHVPELDTQDAEALVGLWPLGSFLVTGRDPSQALVLRSGPLPGEVNTYQIQKIPRGVSLESSNLCMPDLPHLLAFLSASRDVLPRTLLLPPPTLGPRDEHTDPVQIGRVQQDTPGKVLSIVNQLYLETHRGWGREQTPQETEPEAAQRHDPAPRNPAPHGVSWVKGPLSPEVDHP--------------GPALASLLEEEEE---DLEGKEEGRED---DPEEEGPEDVLTIHVQSLVRARSSYVARQYRSLRVRIASDSGGPHGSGDPATELLQDVRHLLTDLQDHLAKDSYIRAVFGSRGPGLPKKDEDPGPALETAVCQAVLAPLKPALWTRLRTLRAPELRRLRRRQTALRAGAGPPGAQGPGPEGQSPAPALRSRIHERLAHLHAACAPRRKVALLLEVCRDVYAGLARGENQDPLGADAFLPALTEELIWSPDIGDTQLDVEFLMELLDPDELRGEAGYYLTTWFGALHHIAHYQPETDRAPRGLSSEARASLHQWHRRRTLHRKDHPRAQANLPFKEPWAEETVTGTSDN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*** * .. ..** ** * .: **::** **** *.* ***** **.*****:: *:*:: ******** *::*.*.*:*::** .*::******::* ************* *********************.**:*. *:*:** ::* :* **.*:***:********* ** :***:*:**:.*: . *** *:** ****: .* **..*. *. ** * . ** :* .:* * *** **:** *:::*. :*********:.**.*: ****.*:..************:******::****. :*****.***.: : :** ***:*.*:*:*** ********:****** ********* ***.**** ****** *** ******************* ** ******. ***::*******************.**:**************.*****************:*******::.***: *********:*********:: :* * * **:**** ", "identical_positions": 371, "similar_positions": 103, "identity": "63.1%" }, { "cls_id": "homologset.agr.MGI:2444029", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTI7-1", "uniprot_id": "ANR52_MOUSE", "id": "Q8BTI7-1", "name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C", "aln": "MGILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSG------ANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSADVNAR---DKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRS--GRSALHHAVHSGHLETVNLLLN---------KGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLSCKD----RKGYGLLHTAAASGQIEVVKHLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVN--YQSKEGKSPLHMAAIHGRFTRSQILIQNGS-EIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARR--GIHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDSLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASDTYRRAEPHTASSHDAEEDELLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTVPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASG---HTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEHSPFSYLEGNP-FTPLHCAVINNQDSTTEMLLG-ALGAKIVNSRDAKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGR--TALMTAAESGQTAAVEFLLYRGKADLTVLD-ENKNTALHLACSKGHEKCALMILAETQDLG-LINATNSALQMPLHIAARNGLASVVQALLSRGATVLAVDEEGHTPALACAPNKDVADCLALILSTMKP---FPPKDAVSPFSFSLLKNCGIAAAKTVGGCGALPHGASCPYSQERHGA-IGLDGCYSE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ACT4-1", "uniprot_id": "D4ACT4_RAT", "id": "D4ACT4-1", "name": "", "aln": "MGILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSGNCVHTGANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSADVNAR---DKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRS--GRSALHHAVHSGHLETVNLLLN---------KGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLSCKD----RKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVN--YQSKEGKSPLHMAAIHGRFTRSQILIQNGS-EIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARR--GIHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDSLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASDTYRRAEPHTASSHDAEEDELLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTVPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASG---HTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEHSPFSYLEGNP-FTPLHCAVINNQDSTTEMLLG-ALGAKVVNSRDAKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGR--TALMTAAENGQTAAVEFLLYRGKADLTVLD-ENKNTALHLACSKGHEKCALMILAETQDLG-LINATNSALQMPLHIAARNGLASVVQALLSRGATVLAVDEEGHTPALACAPNKDVADCLALILSTMKP---FPPKDAVSPFSFSLLKNCGIAAAKTVGGCGALPHGASCPYSQERHGA-IGLDGCYSE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NB46-1", "uniprot_id": "ANR52_HUMAN", "id": "Q8NB46-1", "name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C", "aln": "MGILSITDQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSG------ANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSADVNAR---DKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRS--GRSALHHAVHSGHLETVNLLLN---------KGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLGCKD----RKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVN--YQSKEGKSPLHMAAIHGRFTRSQILIQNGS-EIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARR--GIHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASDTYRRAEPHTPSSHDAEEDEPLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTIPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASG---HTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEHSPFSYLEGNP-FTPLHCAVINNQDSTTEMLLG-ALGAKIVNSRDAKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGR--TALMTAAENGQTAAVEFLLYRGKADLTVLD-ENKNTALHLACSKGHEKCALMILAETQDLG-LINATNSALQMPLHIAARNGLASVVQALLSHGATVLAVDEEGHTPALACAPNKDVADCLALILSTMKP---FPPKDAVSPFSFSLLKNCSIAAAKTVGGCGALPHGASCPYSQERPGA-IGLDGCYSE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q502K3-1", "uniprot_id": "ANR52_DANRE", "id": "Q502K3-1", "name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C", "aln": "MGVLNISDQPPLVQAIFNRNADEVKLFLHKKDEVNALDQERRTPLHAAAWLGDVHIMDLLISAG------ANVNAKDHVWLTPLHRAAASRNERAVGLLLRKGADVTAR---DKYWQTPLHIAAANRATRCVETLLPHVSSLNMADRT--GRAPLHHAAQSGYQEMVKLLLN---------KGANLSASDKKDRQPIHWAAYLGHLEVVKLLVSQGSDKSCKD----KRGYTPLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYTGQEAVANELVNRGANVNQPNHRGYTPLHLAAVSTNGALCLELLVNNGADVN--MQSKEGKSPLHMAAIHGRFTRSQILIQNGG-EIDCVDRYGNTPLHVAAKYGHELLISTLMTNGADTARQ--GIHGMFPLHLAVLYGSSDCCRKLLSSGQLYSIVLSMSKEHVLSAGFDINTPDNFGRTCLHAAASGGNIECLNLLLSSGADMNKKDKFGRTPLHYAAANGRYQCVVVLVGAGAEVNERDRSGCTPLHYSAASTAFCRTDRPHASTHQNQED------GEKESFLCVEHLLDNGADPCLCNTKGYSAVHYAAAHGNKQNLELLLEMCFNTLGDKESNGSISPLHLAVESGHWECVTVLIESGVCVDVCDPVGRSVLYLASQRGHSRCVELLLSQSASCLLAEHRSKWGPLHVAAANG---HSECLRMLLCSEGGADLVNVTDAEGQTPLMLAVLGGHTDCVHLLLERGACPDMKDRRGRTALHRGAVMGREDCLTALLSHNVSVLSRDFQGRSALHLAASCGHADILSNLLSAADHSQPQDPLTDRHGYTPAHWAAYHGHEDCLEVLLELKPCSIQEGNP-FTPLHCALINGHSGSAELLLESSVCNSLVNIRDAKGRTPLHAAAVAEDVAGLQLVLRQGADIDAVDHSGR--SALMVAADYGQSGAVALLLHRAKADLSLLD-VNKNTALHLACSKAHEMCAMLILKEIHNPI-LINATNSMLQMPLHIAARNGLATVVQALLNRGATVLAVDEEGHTPALACASNKAVADCLALILSTMKPSSSTASSSSPSSPSLNLLKHCGITAACPPLPNGGLRHG----YGKDRHGATIGLDGCLTE--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40480-1", "uniprot_id": "HOS4_YEAST", "id": "P40480-1", "name": "Protein HOS4", "aln": "--MNETTTKQPLKKRSLSSYLSNVSTRREELEKISKQETSEEEDTAGKHEQRETLSEEVSDKFPENVASFRSQTTSVHQATQNNLNAKESEDLAHKNDASSHEGEVNGDSRPDDVPETNEKISQAIRAKISSSSSSPNVRNVDIQNHQPFSRDQLRAMLKEPKRKTVDDFIEEEGLGAVEEEDLSDEVLEKNTTEPENVEKDIEYSDSDKDTDDVGSDDPTAPNSPIKLGRRKLVRGDQLDATTSSMFNNESDSELSDIDDSKNIALSSSLFRGGSSPVKETNNNLSNMNSSPAQNPKRGSVSRSNDSNKSSHIAVSKRPKQKKGIYRDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFESVDDESEFDDEEDQKILREIKKRLSIAAKKWTNRAGIHNDKSKNGNNAHTIDQPPFDNTTKAKNEKAADSPSMASNIDEKAPEEEFYWTDVTSRAGKEKLFKAS-----------KEGHLPYVGTYVENGGKIDLR------SFFESVKCGHEDITSIFLAFGFPVNQTSRDN-KTSALMVAVGRGHLGTVKLLLEAGADPTKRDKKGRTALYYAKN-----SIMGITNSEEIQLIENAINNYLKKHSEDNNDDDDDDDNNNETYKHEKKREKTQSPILASRRSATPRIEDEEDDTRMLNLADDDFNNDRDVKESTTSDSRKRLDDNENVG-----TQYSLDWKKRKTNALQDEEKLKSISPLSMEPHSPKKAKSVEISKIHEETAAEREARLKEEEEYRKKRLEKKRKKEQELLQKLAEDEKKRIEEQEKQKVLEMERLEKATLEKARKMEREKEMEEISYRRAVRDLYPLGLKIINFNDKLDYKRFLPLYYFVDEKNDKFVLDLQVMILLKDIDLLSKDNQPTSEKIPVDPSHLTPLWNMLKFIFLYGGSYDDKKNNMENKRYVVNFDG----VDLDTKIGYELLEYKKFVSLPMAWIKWDNVVIENHAKRKEIEGN---MIQISINEFARWRNDKLNKAQQPTRKQRSLKIPRELPVKFQHRMSISSVLQQTSKEPFW", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : ** : :. .:* : :::. : ... . :. :: . .:. .* *.: . : .:*.. *. :* ::: * **. . .: * : .::: :: .* *: :. : *. ::: :. . .. :*: :* : : : : * *:* : * * . . . . .:*:.: : * ** : : * .: . * * :*:*.. :. . :: . .. . : :. : : :.. *:: *::*. :*:: : :*::*. :*: *. ***.** ** ** ::. *: ****. : :.. ** * * * : **..* :* : . . *.. : : *. .:. *: . .: . : :* . : .: ..: .. . . *.: : . :* . : . *: . . .: : : ::**.. * :.. :. *:.: .::* : * ... *.* :*. ** :. * *: . * **:.*: *.: .: : *: : :: * .. . : . : .: .: . : . . * * * . : * : *: . . :: : * . : ..:: * :. :.. : :. : * .*: : ** . . * :: . *: :. : : .: : *. : .. :. : * .* : : :.: . * . . : .:. .: : : *: :*. *: *: ::. . .* :* : .:. :: ::. :* *: . * :* .: * :: * : * . . . * . : : : : : : : . ", "identical_positions": 120, "similar_positions": 342, "identity": "10.71%" }, { "cls_id": "homologset.agr.MGI:2444031", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3T1L5-1", "uniprot_id": "ALG6_RAT", "id": "Q3T1L5-1", "name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------MESWTWMTV-------------------VVLLGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITLNLPVKQWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAKFINPDWVALHTSRGYES--QAHKLFMRTTVLAADLLIYIPAVLLYCYSLKEIS---PKRKIASALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSCDWDLLGSLAFCLALNYKQMELYHSLPFFCFLLGKCFKKGLRGKGSALFIRIACTVVASFLLCWLP--FLTE-REHALQVVRRLFPVDRGLFEDKVANIWCSLNVFLKIKDILPRHIQIAISFCFTFLSLLPACIKLTVQPSAKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLT----EIPFMSTWFLLVSTFSMLPLLLKDQLLLPSVVTVMAFLIACSTFFPMFENTSEEQLQLKSFAVSVRRHLPGFTFLPR--IIQCLFLSSVITMILLTILSVTLDPPQKLPDLFSVLICFVSCVNFVFFLVYFNIVIMWDSKNGRNRKKID", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TAE8-1", "uniprot_id": "ALG6_MOUSE", "id": "Q3TAE8-1", "name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------MESWPWMAV-------------------VVLLGLTVRWTVSLSSYSGAGKPPMFGDYEAQRHWQEITLNLPVKQWYFNSSDNNLLYWGLDYPPLTAYHSLLCAYVAKFINPDWVALHTSRGYES--QAHKLFMRATVLAADLLIYVPAVLLYCYSLKEIS---PKRKIASALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSWDWDLLGSLAFCLALNYKQMELYHSLPFFCFLLGKCFKKGLKGKGLALFIRIACTVLASFLLCWLP--FLTE-REHALQVVRRLFPVDRGLFEDKVANIWCSVNVFLKIKDTLPRHIQIAISFCFTLLSLLPACIKLTVRPSCKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLT----EIPFMSTWFLLVSTFSMLPLLLKDELLLPSVVTVMAFVIACGTFFPMLENTSEEQLQLKSFAVSVRRHLPGFTFLPR--IMQCLFLSSVITMVLLTILSVTLDPPQKLPDLFPVLICFVSCVNFVFFLVYFNIVIMWDSKNGRNRKKIE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y672-1", "uniprot_id": "ALG6_HUMAN", "id": "Q9Y672-1", "name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------MEKWYLMTV-------------------VVLIGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITFNLPVKQWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAKFINPDWIALHTSRGYES--QAHKLFMRTTVLIADLLIYIPAVVLYCCCLKEIS---TKKKIANALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGISCDCDLLGSLAFCLAINYKQMELYHALPFFCFLLGKCFKKGLKGKGFVLLVKLACIVVASFVLCWLP--FFTE-REQTLQVLRRLFPVDRGLFEDKVANIWCSFNVFLKIKDILPRHIQLIMSFCSTFLSLLPACIKLILQPSSKGFKFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLS----EIPFMSTWFLLVSTFSMLPLLLKDELLMPSVVTTMAFFIACVTSFSIFEKTSEEELQLKSFSISVRKYLPCFTFLSR--IIQYLFLISVITMVLLTLMTVTLDPPQKLPDLFSVLVCFVSCLNFLFFLVYFNIIIMWDSKSGRNQKKIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JR12-1", "uniprot_id": "A0AC58JR12_DANRE", "id": "A0AC58JR12-1", "name": "Alpha-1,3-glucosyltransferase", "aln": "-MNSDDTSVSGGCCENYLLLPVKKQDE-----------DAILCRINIIRRSLYPFIYERCAGKPPMFGDYEAQRHWQELTYNLPVHEWYFNTTNNDLNYWGLDYPPLTAYHSLACAYIAKLFNPEWVELHASRGYES--HSHKLFMRATVLFADALIYIPAVLLYCFYFCDGS---PKQKVATAFCILMYPGLMLIDYGHFQYNGVSLGLALWGVLGLGLGWDLFGSVAFVLALNYKQMELYHALPFFCYLLGKCVKHGLNGQGFFHLVKISLTVLVTFALCWMP--FLSD-PKQPLQVLHRLFPVGRGLFEDKVANTWCSLNVLIKIKTLLSRETQLFLSFALTVLFVLPSSLKLLSKPTLWQFKLALVNSSLAFFLFSFQVHEKSILLAALPVCLVIN----EMPLIAVWFLLTSTFSMLPLLLKDGLLLPYVVTSLAFLFLSLYLLSALERSTDEELRLAPYRKLTQHFLPKLN-LSR--IVKWKFWLSLVAMAALSITSVWLEPPAKLPDLFPVLVSIFSFLHFLGFVIYFNLVQLMEPQRRKNQKKTN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKX7-1", "uniprot_id": "ALG6_DROME", "id": "Q9VKX7-1", "name": "Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "-------------MRSEILASA---------------------FLGLAVRSIISLYSYSGFDSPPMHGDYEAQRHWQEITVNLAVGEWYTNSSNNDLQYWGLDYPPLTAYHSYLVGRIGASIDPRFVELHKSRGFES--KEHKRFMRATVVSADVLIYLPAMLLLAYSLDKAFR--SDDKLFLFTLVAAYPGQTLIDNGHFQYNNISLGFAAVAIAAILRRRFYAAAFFFTLALNYKQMELYHSLPFFAFLLGECVSQKSFASFIAEISRIAAVVLGTFAILWVP--WLGS-LQAVLQVLHRLFPVARGVFEDKVANVWCAVNVVWKLKKHISNDQMALVCIACTLIASLPTNVLLFRRRTNVGFLLALFNTSLAFFLFSFQVHEKTILLTALPALFLLK----CWPDEMILFLEVTVFSMLPLLARDELLVPAVVATVAFHLIFKCFDSKSKLSNEYPLKYIAN-------------------------ISQILMISVVVASLTVPAPTKYPDLWPLIISVTSCGHFFLFFLWGNVQQFSSKLS--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12001-1", "uniprot_id": "ALG6_YEAST", "id": "Q12001-1", "name": "Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "aln": "MAIGKRLLVNKPAEESFYASPMYDFLYPFRPVGNQWLPEYIIFVCAVILRCTIGLGPYSGKGSPPLYGDFEAQRHWMEITQHLPLSKWYWY----DLQYWGLDYPPLTAFHSYLLGLIGSFFNPSWFALEKSRGFESPDNGLKTYMRSTVIISDILFYFPAVIYFTKWLGRYRNQSPIGQSIAASAILFQPSLMLIDHGHFQYNSVMLGLTAYAINNLLDEYYAMAAVCFVLSICFKQMALYYAPIFFAYLLSRSLLFPKFN--IARLTVIAFATLATFAIIFAPLYFLGGGLKNIHQCIHRIFPFARGIFEDKVANFWCVTNVFVKYKERFTIQQLQLYSLIATVIGFLPAMIMTLLHPKKHLLPYVLIACSMSFFLFSFQVHEKTILIPLLPITLLYSSTDWNVLSLVSWINNVALFTLWPLLKKDGLHLQYAVSFLLSNWLIGNFSFITPRFLPKSLTPGPSISSINSDYRRRSLLPYNVVWKSFIIGTYIAMGFYHFLDQFVAPPSKYPDLWVLLNCAVGFICFSIFWLWSYYKIFTSGSKSMKDL---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : * : ..**:.**:****** *:* :*.: :** :* ***********:** . :. ::* :. *. ***:** : * :**:**: :* *:*.**:: : . : : *. *** ******.: **:: .: : .:. * *:: :*** **:: **.:**.... : :: .: :* : : * :: : * ::*:**. **:******* ** **. * * :. . .: *.: **: : : . : .*. :::***********:**: ** :: . : .: *:: *** :* * : .*: : * . : : * . : .* * ***: :: . . * * :: : . ", "identical_positions": 126, "similar_positions": 125, "identity": "22.78%" }, { "cls_id": "homologset.agr.MGI:2444036", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZYJ1-1", "uniprot_id": "A0A8I5ZYJ1_RAT", "id": "A0A8I5ZYJ1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSPSPAHPQLPILQTQMVSDGMTGSNPVSPASSSSPASS---------GAGGISPQHIAQDSSLDG-----------PPGP-----QDGTTVPLEGFSLS--HAADPINRG----------------------------------------------------------------------------------------------------------------------------------------------PKWEKSHAEIAEQAKHEAEIETRIAELRKEGFWSLKRLPKVPEPPRPKGHWDYLCEEMQWLSADFAQERRWKRGVARKVVRMVIRHHEEQRQKEERARREEQAKLRRIASTMAKDVRQFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQSLNQPLASSKAGSSPCLGSSSAASSPPPPVSRLDDEDGDFQPQEEEEEDDEETIEVEEQQEGNDAETQRREIELLRHEGELPLEELLRSLPPQLLGGPFSPSQTP-SHDSDTPDGPEENIEEEPSQDLEVDPPSSSVTQCNKQCWHPDEDDEEFTANEDEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAYAYDASAPGSGNSEDEEEVEANSSDCELEETRDVEEAAQEDSSSQSDSAEEHSEDEEDEHSEEE-MSGSSQSEESESDESEDAQSQSQADEEQEDEG------DDDDDDFGVEYLLARDDERSEVDGGSGPPTPGPTTTLGPKKEITDIAAAAESLQPKGYTLATTQVKTPIPLLLRGQLREYQHIGLDWLVTMYEKKLNGILADEMGLGKTIQTISLLAHLACEKGNWGPHLIIVPTSVMLNWEMELKRWCPSFKILTYYGAQKERKLKRQGWTKPNAFHVCITSYKLVLQDHQAFRRKNWRYLILDEAQNIKNFKSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQSHR---------EFKEWFSNPLTGMIEGSQEYN-----EGLVKRLHKVLRPFLLRRVKVDVEKQMPKKYEHVIRCRLSKRQRCLYDDFMAQTTTKETLATGHFMSVINILMQLRKVCNHPNLFDPRPVTSPFITPGICFSTASLVLRATEVHPLQQIDMGRFDLIGLEGRVSRYEADTFLPRHRLSRRILLEIATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNSPRAPLGPVPVRPPPGPEVSTQPTLGPVPPVLPTPLMVSASPAGTPVVPASRPPGPVLLSPLQPNTGPLPQVLPSPMGVMSGTSRPPTPTLSLKPAPPAPVRLSPAPPPGSSSLLKPLTVPPGYTLSPVAATTTSSTIATVTTTAVPAPNSTPQRLILSPEMQARLPSGEVVSIGQLASLAQRPVTSAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLP-STPSTTPAPTGLSLPLAANQVPPSMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPSSSGLPAVLTPRPTLTPSRLTSPTLGTTRTPIPTPTLVRPLLKLVHSPSPEVSASAPGAAPMTISSSLHMPSSLPGPASSSMTIHNSSPLSSPVVSSTVSVPVSSSLPISVPTTLPVPASAPLTIPITAPLPVSDLGPALLTGVTPALA-VVSAASGPP-LASAGVSPSVSALALGLATTPALSPPQTSGHSLLLATTSSHVPGLNSAVAPACSPVLVPASALTSPFPISPSSAPAQASLLAPAPSTSQALATSLAPMAASQTTILGPSPTPPLAPLPVLAAS----------QTPLPAMTPPSMSGAPLPSSTLVSAPTSVLAPSSTQTLVSTPVSSPLSSLASTQTLTLAPTLAPTLGGLSPSQTHSLGTGSPQGPFPIQTLSLTPASSLVPTPAQTLSLAPGGPVGPTQTLSLA------PSSPVGPAPAHTLTLAPAASSASLLVPTSVQTLTLSPAPVPVPTLDPSATQTLALAPALTQAPASQASSLVS-ASGAASLPVTMVNRLPVPKDEPETLTLRSGPPSPLPTATSFSGPRPRRQPPPPPRSPFYLDSLEEKRKQQRSERLERIFQLSEAHGALAPVYGTEVLDFCT-LPQPVASPIGPRSPGPSHPIFWTYTEAAHQ--------------AVLFPQQRLDQLSEIIERFIFVMPPVEAPPPSLHACHPPPWLAPHQAAFQEQLACELWPRARPLHRIVCNMRTQFPDLRLIQYDCGKLQTLAVLLRQLKAEGHRVLIFTQMTRMLDVLEQFLTYHGHLYLRLDGSTRVEQRQALMERFNADKRIFCFILSTRSGGVGVNLTGADTVVFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTTAYFKQQTIRELFDMPLEEPPGSSVSSV--------------PEEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAELAEFNENEGFPAGEGEEASRPGPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDEMSCATSGVSHRRSKKVKAPERLGTRVSERLRGARAETQGANHTP---------VTSSHQTCNTFVPPRCSPVRERIPR-----PRPAPPPAPPAPPPAASPAPAPAPAPPAPPPPVLPPVLPPVPPPPPAPSPPAPSPAPPPPAPAASVASAPASAITSSLATAPIP-------------------ISAPNPVTILPVHILPSPAPLLQLPPCSSPASTPP----------------------------------------------------------------------------SACTPLPTCTPLPAQTSLLTSSSPAPLDS--LPVPISPGVTN--------------------------LLLDSG-EVEVCTQELAP---------------VESLELPGMTNSEASLVS-------LVPPNDLLPVAVDVLPESEKNLPLIP-----APSSTLEAESIPDDQEQEVPGSVEGTNRTLLPGGGELTVSLSESNGLELP----------PSAASDEPL-QLLETHRNLED------TREVQTPVSNSEKPQELVRAEVTAPSTSSSATSSPEGPLPARPPRRRTSADVEIRGQGS------------------------GRTGQPPGPKVLRKLPGRLVTVVEEKELVKRRR-HRATASTLVPG------------------------------VSEVSASPRSPSIHSMSGPESS-----PPSSGPCEAAPTSSLSTPTQHTFIACRHNELG----ITGGGSPENGEGAKLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPS---------SISKGKTNGVDPIPGPETVTATAAEPDLK--------------------------PQPLAPQPVHK----PEPIILSPVEKRRRGRPPKARDLPIPGTISSPGDGNLESRTQPLPFPATLT---------------PLLACPTA-VANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQ--HPVLDPDSSSVLESCGLGVQRQPLGQAESEGSSSDEDGS----RPLTRLARLRLEAEGMRGRKSEGSMVMAVIQD----------------------------------------------------------------------------------------------------DLDLADSGPSGLELTPPVVSLTPKFRSTRLRPGSLVPPLETEKMPRKRSGAPVG--------------SSGMAKRGRLQPPSPLGPEGSVEESE---------------------AEASGDEEEGDGTPRRRTGPRR------------------LVGTTNQGDQRILR---SSAPPHLSIPTISHRG-----RKAKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A087WQ44-1", "uniprot_id": "A0A087WQ44_MOUSE", "id": "A0A087WQ44-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSPSTAHPQLPILQTQMVSDGMTGSNPVSPASSSSPDSS---------GAGGISPQHIAQDSSLDG-----------PPGP-----QDGTTVPLEGFSLS--HAADLVNRG----------------------------------------------------------------------------------------------------------------------------------------------QKWEKSHAEIAEQAKHEAEIETRIAELRKEGFWSLKRLPKVPEPPRPKGHWDYLCEEMQWLSADFAQERRWKRGVARKVVRMVIRHHEEQRQKEERARREEQAKLRRIASTMAKDVRQFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQSLNQPPASSKAGSSPCLGSSSAASSPPPPVSRLDDEDGDFQPQEEEEEDDEETIEVEEQQEGNDAETQRREIELLRHEGELPLEELLRSLPPQLLGGPFSPSQTP-SHDSDTQDGPEENIEEEPSQDLEVHPPSSAVTQCNKQRWHPDEDDEEFTANEDEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAYACDASAPASGDSEDEDEVEANSSDGELEET--VEEAAQEDSSSQSDSAEECSEDEEDEHSEEE-MSGSSQSEESESDESEDAQSQSQADEEQDDEGEDDDVDDDDDDGFGVEYLLARDDERSEVDGGSGPPTPGPTTTLGPKKEITDIAAAAESLQPKGYTLATTQVKTPIPLLLRGQLREYQHIGLDWLVTMYEKKLNGILADEMGLGKTIQTISLLAHLACEKGNWGPHLIIVPTSVMLNWEMELKRWCPSFKILTYYGAQKERKLKRQGWTKPNAFHVCITSYKLVLQDHQAFRRKNWRYLILDEAQNIKNFKSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQSHR---------EFKEWFSNPLTGMIEGSQEYN-----EGLVKRLHKVLRPFLLRRVKVDVEKQMPKKYEHVIRCRLSKRQRCLYDDFMAQTTTKETLATGHFMSVINILMQLRKVCNHPNLFDPRPVTSPFITPGICFSTASLVLRATEVHPLQRIDMGRFDLIGLEGRVSRYEADTFLPRHRLSHRILLEIATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNSPRPPLGPVPVRPPPGPEVSAQPALGPVPPVLPAPLMVSASPAGTPVVPASRPPGPVLLSPLQPNTGPLPQVLPSPVGVMSGTSRPPTPTLSLKPAPPAPVRLSPAPPPGSSSLLKPLTVPPGYTLSPVAATTTSSTIATVTTTAVPAPNSTPQRLILSPEMQARLPSGEVVSIGQLASLAQRPVTSAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALVQAVAPTPGPTPVSVLP-STPSTTPAPTGLSLPLAANQVPPSMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPSSSGLPAVLTSRPTLTPSRLSSPTLGTTRTPIPTPTLVRPLLKLVHSPSPEVSASAPGAAPMTISSSLHMPSSLPGPASSPMTIHNSSPLSSP-VSSTVSVPVSSSLPISVPTTLPVPTSAPLPIPITAPLPVSDLGPALLTSVTPALA-VVSAASGPP-LASAGVSPSMSALALGLATTPALSPPQTSGHSLLLATTSSHVPGLNSAVAPACSPVLVSASALTSPFPVSPSSAPAQASLLAAAPSTSQALATSLAPMAASQTAILGPSPTPPLAPLPVLAAS----------QTPLPAMTPPSMSGTPLPSSSLVSAPTSVLAPSSTQTLVSTPVSSPLSSLASTQTLTLAPTLAPTLGGLSPSQTHSLGTGSPQGPFPIQTLSLTPASSLVPTPAQTLSLAPGGPVGPTQTLSLAPVPPLPPSSPVGPAPGHTLTLAPAASSASLLVPTSVQTLTLSPAPVPVPTLDLSATQTLALAPALTQAPASQASSLVS-ASGAASLPVTMVNRLPVPKDEPETLTLRSGPPSPLPTATSFSGPRPRRQPPPPPRSPFYLDSLEEKRKQQRSERLDRIFQLSEAHGALAPVYGTEVLDFCT-LPQPVASPIGPRSPGPSHPIFWTYTEAARR--------------AVLFPQQRLEQLSEIIERFIFVMPPVEAPPPSLHACHPPPWLAPHQAAFQEQLACELWPRARPLHRIVCNMRTQFPDLRLIQYDCGKLQTLAVLLRQLKAEGHRVLIFTQMTRMLDVLEQFLTYHGHLYLRLDGSTRVEQRQALMERFNADKRIFCFILSTRSGGVGVNLTGADTVVFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTTAYFKQQTIRELFDMPLEEPPGSSVSSV--------------PEDEEEAVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAELAEFNENDGFPAGEGEEANRPGPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPHEEEEGPGAGDEMSCGSSGASHRRSKKIRAPERLGTRVSERLRGARAETQGANHTP---------VTSSHHTCNTFVPPQCSPVRERIPRPV---PRPRPPPPPPAPPPPPAPPASPSPAPPPPPAPASP------APPAPPASPPAASPSPAPLPPAASVASA----ITSALATAPIP-------------------ISAPNPVTILPVHILPTP-PLLQLPPSSSPASTPP----------------------------------------------------------------------------SACTPLPTCTPLQAQTSVLTSSSPAPLDS--LSVPISPGVTN--------------------------LPLDSG-EVGLCAQELAP---------------VESLELPGMTNSEASLAS-------LVSPKDLLPVAVDILPESEKTLPCIP-----APSSTLEAESIPNGQQQEVPGPVEGTNTTLLPGSEELTMSLNESNGLELP----------PSAASAEPLDELLETHRNSGE------TREVQIPISNSEKPQELVRAEVTAPSTSSSATSSPEGPLPARPPRRRTSADVEIRGQGS------------------------GRTGQLPGPKVLRKLPGRLVTVVEEKELVKRRR-HRAPASTLVPG------------------------------VSEVSASPRSPSIHSMSGPESS-----PPSSGPCEAAPTSSLSTPTQSTFIACRHNELG----TTTGGSPENGEGTELAITPPAVKRRRGRPPKKNRSPADAGRGVDEVPS---------SISKGKTNGVDPVPGPE--TVTVAEPDLRPQ--------------------FVPGPQPPGPQPVHR----PEPTILSPVEKRRRGRPPKARDLPIPGTISSPGGGNLESRTQSLPFPAPLT---------------PLLACPTA-VTNTVTTVTISTSPPKRKRGRPPKNPPSPRPSQ--HPVLDPDSSSILESCGLGVQRQPLGQAESEGSSSDEDGS----RPLTRLARLRLEAEGMRGRKSEGSMVMAVIQD----------------------------------------------------------------------------------------------------DLDLADSGPSGLELTPPVVSLTPKFRSTRLRPGSLVPPLETEKMPRKRSGAPVG--------------SSGMAKRGRLQPPSPLGPEGSVEESE---------------------VEASGDEEEGDGTPRRRTGPRR------------------LVGTTNQGDQRILR---SSAPPHLCIPTISHRG-----RKAKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZRS2-1", "uniprot_id": "SRCAP_HUMAN", "id": "Q6ZRS2-1", "name": "Chromatin remodeling protein SRCAP", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSPSPAHPQLPVLQTQMVSDGMTGSNPVSPASSSSPASS---------GAGGISPQHIAQDSSLDG-----------PPGP-----PDGATVPLEGFSLS--QAADLANKG----------------------------------------------------------------------------------------------------------------------------------------------PKWEKSHAEIAEQAKHEAEIETRIAELRKEGFWSLKRLPKVPEPPRPKGHWDYLCEEMQWLSADFAQERRWKRGVARKVVRMVIRHHEEQRQKEERARREEQAKLRRIASTMAKDVRQFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQSLNQPLTSSKAGSSPCLGSSSAASSPPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAYAPGS---GSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEE------------EEDDDFGVEYLLARDEEQSEADAGSGPPTPGP-TTLGPKKEITDIAAAAESLQPKGYTLATTQVKTPIPLLLRGQLREYQHIGLDWLVTMYEKKLNGILADEMGLGKTIQTISLLAHLACEKGNWGPHLIIVPTSVMLNWEMELKRWCPSFKILTYYGAQKERKLKRQGWTKPNAFHVCITSYKLVLQDHQAFRRKNWRYLILDEAQNIKNFKSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQSHR---------EFKEWFSNPLTGMIEGSQEYN-----EGLVKRLHKVLRPFLLRRVKVDVEKQMPKKYEHVIRCRLSKRQRCLYDDFMAQTTTKETLATGHFMSVINILMQLRKVCNHPNLFDPRPVTSPFITPGICFSTASLVLRATDVHPLQRIDMGRFDLIGLEGRVSRYEADTFLPRHRLSRRVLLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASP-VSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLS--PAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSERLERIFQLSEAHGALAPVYGTEVLDFCT-LPQPVASPIGPRSPGPSHPTFWTYTEAAHR--------------AVLFPQQRLDQLSEIIERFIFVMPPVEAPPPSLHACHPPPWLAPRQAAFQEQLASELWPRARPLHRIVCNMRTQFPDLRLIQYDCGKLQTLAVLLRQLKAEGHRVLIFTQMTRMLDVLEQFLTYHGHLYLRLDGSTRVEQRQALMERFNADKRIFCFILSTRSGGVGVNLTGADTVVFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTTAYFKQQTIRELFDMPLEEPSSSSVPSA--------------PEEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAELAEFNENDGFPAGEGEEAGRPG--AEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTP---------VISAHQTRSTTTPPRCSPARERVPRPA---PRPRPTP----------------------------------------ASAPAAIPALVPVP-----------------VSAPVP-------------------ISAPNPITILPVHILPSPPPPSQIPPCSSPACTPP----------------------------------------------------------------------------PACTPPPAHTPPPAQTCLVTPSSPLLLGP--PSVPISASVTN--------------------------LPLGLRPEAELCAQALAS---------------PESLELASVASSETSSLS-------LVPPKDLLPVAVEILPVSEKNLSLTPS----APSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELP----------PSAASDEPLQEPLEADRTSEE------LTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGT------------------------GRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPG------------------------------VSETSASPGSPSVRSMSGPESS-----PPIGGPCEAAPSSSLPTPPQQPFIARRHIELG----VTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPS---------STLKGKTNGADPVPGPE--TLIVADPVLEPQ--------------------LIPGPQPLGPQPVHR----PNP-LLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLP------------PLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQ--LPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGS----RPLTRLARLRLEAEGMRGRKSGGSMVVAVIQD----------------------------------------------------------------------------------------------------DLDLADSGPGGLELTPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAPVGG-------------SPGLAKRGRLQPPSPLGPEGSVEESE---------------------AEASGEEEEGDGTPRRRPGPRR------------------LVGTTNQGDQRILR---SSAPPSLAGPAVSHRG-----RKAKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B358-1", "uniprot_id": "A0A8M2B358_DANRE", "id": "A0A8M2B358-1", "name": "", "aln": "MAEGSSTDHCQDWSQHHGDTGGVSAPFQTAKGPLPPETIKLDYKNVSGKDTSGESPSAPKTEVTPSVKGAVKSTDKDMEHPKPTPLFETNQTAASSVLQKQSTTNSATQLCKFDSKETMEDVTRDLLKTSKEDDISETLSAGGTKQGISGNSICSGYSSKQGGQHITPNRGNNTPNDSDKGSCYLTETCSQTQTSTQKTSTLPKTPGIPTLVENIQCVQELSSQYLHINPKMVTLSKETSTRGDLYCNVAAKEVLCNVSVDEPKLSGHGTCTDTAHVSIMSERSQVMGCGSSDVILKQNDSANQIEISMSSNHQQDGSILLTHAENCVTSEGLESDQPNLSDCLVQQLQESIPTDHKLSQIQICLNNTPDIVNEEERQEMNAEALSAVEVKDLIDVGILMQPDMEDTWLVVSEIDGQPEHGEMEVSDESLVQCPESQSTVAVYECTVPCFTSAAIHSDVKLLLTDKEEEPMETLTQDLQVQSNLGSHPATLKSTKELTIMSSAQKEVAAIVKQNNDSSPTLAKTMTGLTSTLLDVTLDSVHDQQESVVVENTPGVSLISLGTIDPKLLILKKDDRPALKQPSSLSARVATKQNSSILDRSPSNESNKVSECLAKTDTAASSNLKDVKLPADHPVSNTLSQSWTVSTSNVLSQNSSEKEKLYQSSSSGKMLQKESSADTSLSTSVKLHNSESHLTPSPGGVWGPVSDIVPLENQSLDGKPLQDLMSLGGALVLEQQQLPDKLLSTAQDSQHTILEPLDASVEESSDGEADSSLEVQNEDSNAVTNPAENKRGQSRTDRQDLLLKVCQWIAGKVTAASTPSTSPVPCSSPSPSSSDWIRSHTGRTSPIRNSNGKNMPSTSSQGSQSEQTTTPKSTPKHTDLAELAKHEAEIEHRTLALKREGFWSLKRLSRITEPVRPKDHWDYLCEEMQWLSADFAQERRWKRGVARKVVRMVMRHHEELRQKEERAKREEQAKLRRVASSIAKEVRAFWSSVEKVVQYKQQSRLEEKRKKALDLQLDFIVGQTERYSDLLSQSLQG---------APVQSSDTAAASKQSQPNPVDEDDRDFEPP-CEEEDDEETIEVEEQQEGNDAETQKREIELLREESTLPLDQLLSTLT--------------------LPQDVESEEEESDTSSLTVE-----------------DEDKEFSANEEDAEDEEETIEAQEVIEGEGDHTEELDDLAREGEMSMEELLEKYRGAYASDFEEPSASADSSE---ESEGTEVEAEEETEGEDSAD-DSGSSSDSQAAVDTEEEDEHEDVQ--------------ESDD----------------------EDDGGEGMEVLLREGDQ-----------SPSVPTSPRPKKEISHIAATAESLQPKGYTLATTKVKTPIPFLLHGTLREYQHIGLDWLVTMNEKKLNGILADEMGLGKTIQTIALLAHLACVKGNWGPHLIIVPTSVMLNWEMELKRWCPGFKILTYYGSQKERKLKRQGWTKPNAFHVCITSYKLVLQDHQAFRRKSWRYLILDEAQNIKNFKSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQSHR---------EFKEWFSNPLTGMIEGSQEYN-----EGLVKRLHKVLRPFLLRRIKADVEKQMPKKYEHVVRCRLSKRQRFLYDDFMAQASTRETLASGHFMSVINILMQLRKVCNHPNLFDPRPIQSPFITKDIIYSTASLVQQALETSPFERCDLSMFDLVGLEHRVSRYQADVFLPQRKVTHQLIQEIMESPDPPPRPKPVRMKVNRMLQPLPKTDGR--SAANSPR------PACPPTTTTIQT-----------PKPLITEVTTSQAPSQPATQ------VCPVTPVTALRAPLAPSTIPSAPAVRPPAPQSVTVRPSAPSTITAAPPPQPQ----------PP------------------------QPSSIMTQRVLLSPDMQARLPSGEVVSIAQLASLAGRPVSSSQGSKPVTFQLQGNKLTLSGTPLHQVPVPQPRPIQGNVMHLVSSSGQHHLISQPAQVAVLHTVSQS---VSSSANP-HPASTTPTCSGLAVPFTTAQVATSMVGGPGIVKIVVRQAPSKEGGSIPTLAVPP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPRPAPPQSVTLHPHGSPSPVLRAPTASQLPQRPPVYAAPPR----------------------------------------------------------------------TVASSQTPPARPVLRVLQG---------------------------------------------------------------PPPPPAPEP-----------------------------------------------------------------------PVTKANTPCEDSNEVITLRMSTPKPTSSSQSSSSASHRPRIQPPAPPRSPFYMSWLADTRKAQRDDRISQIMRINELHCTAKPVYGREVLDFLTFLPGPCPSPARPVVNNWSYSGYSSCLIAQSQHTSNILERNTFLREEIHNSEERLRLLSDVIDRFVFVIPPVEARPVTMHSCHPPPSLRHQQAVFSSDLSSYVSPLTHTLHRIQSNMRTYFPDLRLIQYDSGKLQTLHLLLRRLKAEGHRVLIFTQMTRMLDVLEQFLNYHGHIYLRLDGSTRVEQRQALMDRFNADRRIFCFILSTRSGGVGVNLTGADTVVFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTTAFFKQQTIRELFDVTEGEKKEAEQSVP--------------QSDDEESINKQKTTILEQALCRAEDEEDIVAASQAKAEQVAELAEFNENIPLDDGDSRDQ-------EEEELSKAEQEIAALVEQLTPIERYAMNFLEASLEDICKEELKQAEEQVEAARKGLDQAKEEGLKLHQSSDSDEEDSVHPSTDEP-TPSRRPRKHKEKGAPSTRVSGRLRGTPADDISLTQTSPDRGRRTAWLNSERSISQTPGSTQKSPLNREVPEKLRSGPRGRCTTKESASLENQTIPTNQQLIDSTTLSPAMRDSYPKISVPSPHQQSISPSSSVPSAAASPSLDRNSCGHLSSSTVACREDSEDQKGEARSENVQSRDRRASASSDSICSPEHHSEQEGQLSLSPTLASPNSRSPRKRQSAEWEILKGLPEDSPSAKVLRKLPGRLVTVVEEKEPKRRRRGVSGSGGLHEGSSEEPEKTEPVQDTVPHSSDGSTQTFKVSPPKSVLTSLHSSPPPTPREQEQTSSPLPYSCTGRGHNPCSPTHHSPDMPVLRNLPVRRRLETESRLAAQLGEQFLGRGRGVDRKSASTQKRIETSTDKDGSTPCDSSLMSRRKRGRPPKTPPRALELSEENTPVIEKTSPERS-----PPHSPKRKRGRPRKDSTTTTGSPPSSPSAGAPSSQEPNLSRSNVMPETLPTDSKISPISSPTLCPTSPLNAAEVSSPPKPDSEIIQTTTSVLLSTSPSETGVDSHVDTYASPNTISSCNDSDNSTLVSLSHSTSTAAPYETCTDSSPTLQFTYSFREPPVTTVSICAEEIAHTSVLSDASEITAYSESLTVSTAAVEAEENSVTDNQQVNNLQPSNTSTQVTSQCEDETDPTTDLPQTTLEPIYSVAESSTPTDQPSIQPSSPPALTSEIEPEASSSILEAPETSAVQTVSTVQRSLPQSEQISPPSQLQTTAMEAVSDSPSQQISSSSLQSLSATNPVTTDSLSTLSTDADSSQSQNIVVETMIDNHEGPHSPKEKVETEEEEVLTEEEVVTEEEE-----------QEVVTETEVVTETEKMETDSVGEDDAGEKDDILSQPKKRRLECLPKDQTPSASGVASSDIESHDVQKSDGPDKPLEEEEPEDK---------EPRSSIRTRSISRQSSQETVRSSSPSSVSSCGTRSSRSKKAAENKNPVKRKRSEIKSEKKKSKEGSDKKHQSNSSSSSSDSEDSNSVKRCLTRSAQKKLEKEGMIAKNDESSTRQKARSDKKAKSTNSTEGESSGEVCSRVTRKSTGPQPNTLASPEPEVLGKRCSALNAAAKLLAMRARGPDTPSSSPKNKTAAHQSKTLTSEKVSKPKVNPGQDSPKVSNNKAESGKQPLGQSTESPQSSSSARSTRQRPGSLVPPLEVERVKKEEKKKPSDQKEEGEDEIRETRSSRGHSACSSISSERGVGSSRSRSSSNSSQRTHSLSSQSTDPIRTRSRATSSGSDTERSKSIQRKNDGGRGRESRKENKSQKLDKAELSAGSGDGTPDRVLRSVAALAAAHALTPACNTRSSTSQKRHSKT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q05471-1", "uniprot_id": "SWR1_YEAST", "id": "Q05471-1", "name": "Chromatin remodeling protein SWR1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTSRKSHAKDKKAGGEQDLADLKFRYDLLTNELFHLREFVSLVDYDPTHFNDSESFQKFLRETHLSLEER---GEKFTDDVAKKGTNGDLTRRRRNLRTSTVVSSETTNE-----------------KKGDIELKLESIA-------------------------PLVRNKCEELKYKLSDHSNRKSIVPQKRPIQHLKKREAAKSLKFKSERKE-----------------NPLPLHEHIAEERYDHIAKVEEPSEAFTIKCPSDDSSFENTSEHYSDNFYFTTSSEEEDIKKKRGRKKKKPRIKLVVH---PPKQTITNPLHVVKPGYESLHEYIASFKS-LEDDLTLEEYNKYIDEQRRLLSRLKKG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IENGALKYDKETDSLQPITSKEIKTIITYKPDPISYFYKQQDLQIHTDHLINQGIHMSKLFRSSTKARIARAKKVSQMIEQHFKHVAGAEERKAKEEERHKKSLARFAVQAVKKRWNMAEKAYRILRKDEEEQLKRIEGKQHLSKMLEKSTQLLEAQLN----------------------------------QVNDDGRSSTPSSDSNDVLSESDD-----DMDDELSTSSDEDEEVDADVG-----------------------------------LENSPASTEATPTD--------------ESLNLIQLKEKYGHFNGSSTVYDSRNKDEKFPTLDKHESSSSESSVMTGEESSIYSSSENESQNENDRESDDKTPSVGLSALFGKGEESDGDLDLDDSEDFTVNSSSVEGEELEKDQ------------------------------------------------VDNSAATFER-----------------AGDFVHTQNENRDDIKDVEEDAETKVQEEQLSVVDVPVPSLLRGNLRTYQKQGLNWLASLYNNHTNGILADEMGLGKTIQTISLLAYLACEKENWGPHLIVVPTSVLLNWEMEFKRFAPGFKVLTYYGSPQQRKEKRKGWNKPDAFHVCIVSYQLVVQDQHSFKRKRWQYMVLDEAHNIKNFRSTRWQALLNFNTQRRLLLTGTPLQNNLAELWSLLYFLMPQTVIDGKKVSGFADLDAFQQWFGRPVDKIIETGQNFGQDKETKKTVAKLHQVLRPYLLRRLKADVEKQMPAKYEHIVYCKLSKRQRFLYDDFMSRAQTKATLASGNFMSIVNCLMQLRKVCNHPNLFEVRPILTSFVLEHCVASDYKDVERTLLKLFKKNNQVNRVDLDFLNLVFTLNDKDLTSYHAEEISKLTCVKN----------------------------------------------------------------------FVEEVN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------KLRETNKQLQEEFGEASFLNFQDANQYFKYSNKQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLEGTVDMLNFLKMVNKLRCDRRPIFGKNLIDLLTKDRRVK--------------------YDKSSIIDN---------ELIKPLQTRVLDNRKIIDTFAVLTPSAVSLDMRKLALGLNDDSSVGENTRLKVMQNCFEVSN-PLHQLQTKLTIAFPDKSLLQYDCGKLQKLAILLQQLKDNGHRALIFTQMTKVLDVLEQFLNYHGYLYMRLDGATKIEDRQILTERFNTDSRITVFILSSRSGGLGINLTGADTVIFYDSDWNPAMDKQCQDRCHRIGQTRDVHIYRFVSEHTIESNILKKANQKRQLDNVVIQEGDFTTDYFSKLSVRDLLGSELPENASGGDK----------------PLIADADVAAKDPRQLERLLAQAEDEDDVKAANLAMREVEIDNDDFDESTEKKAANEEEEN-----HAELDEYEGTAHVDEYMIRFIANGYYY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9NDJ2-1", "uniprot_id": "DOM_DROME", "id": "Q9NDJ2-1", "name": "Chromatin remodeling protein domino", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNEGNSAGGGHEGLSPAPPAVPDRVTPHSTEISVAPANSTSTTVRAAGSVGAALPATRHHQHIATQVKGIASSSSKQQKQLASAQLPVPLSPLPQQQQQTAEATAAAAAPAHSNVSVSSSTIEASVLPPQAK---RQRLDDNEDRTSAASIVGPAESSNIVSSLLPASVASSSEVGGLSSTALQDLNALKKRILQQKLQILRNLKERHLENVSEYFYLQNGGSMMDYPAWRKKTPTPQFISYSNANRIDQLIHEDKPSTSAAAAAAQNQKYTTQQTDSVESSLVSGIGTGATKGAPLDGNISNSTVKTNTQSQVPSKIGSFTESTPAATESNSSTTVPGTATSGAATSTSATSAEASGNVLAVEAEIKIPAVGATPVAISTKLPAAVVQLTQQGGTPLLPCNTS-AGSTALRRPQGQNNASSGSAAASGGGGSLTPTPLYTGNGPAALGGSGGLTPGTPTSGSLLSPALG-----------------------------------------------------------------------------------------------------------------------------------------GGSGTPNSAAQEFSFKAKQEVYVMQRISELQREGLWTERRLPKLQEPSRPKAHWDYLLEEMVWLAADFAQERKWKKNAAKKCAKMVQKYFQDKATAAQRAEKAQELQLKRVASFIAREVKSFWSNVEKLVEYKHQTKIEEKRKQALDQHLSFIVDQTEKFSQQLVEGMNK------------SVADTPSLNSSRLTSPKRESDDDFRPESGSEDDEETIAKAEE-----DAADVKEEVTALAKESEMDFDDFLNDLPP------------------GYLENRDKLMKEEQSSAIKTETP--------------DDSDDSEFEAKEASDDDENTISKQEEAEQEIDHKKEIDELEADNDLSVEQLLAKYKSEQPPSPKRRKLAPRDPELDSDDDSTAVDSTEESEDAATEDEEDLSTVKTDTDMEEQDEQEDGLKS-------------------------------------LMADADATSGAAGSGS-----------------TAGASGNKDDMLNDAAALAESLQPKGNTLSSTNVVTPVPFLLKHSLREYQHIGLDWLVTMNERKLNGILADEMGLGKTIQTIALLAHLACAKGNWGPHLIVVPSSVMLNWEMEFKKWCPGFKILTYYGSQKERKLKRVGWTKPNAFHVCITSYKLVVQDQQSFRRKKWKYLILDEAQNIKNFKSQRWQLLLNFSTERRLLLTGTPLQNDLMELWSLMHFLMPYVFSSHR---------EFKEWFSNPMTGMIEGNMEYN-----ETLITRLHKVIRPFLLRRLKKEVEKQMPKKYEHVITCRLSNRQRYLYEDFMSRAKTRETLQTGNLLSVINVLMQLRKVCNHPNMFEARPTISPFQMDGITFHTPR-----LVCDIMEYDPFTQINLETLNLLLLHLEQTMTAYVSHKSRLLAPPRK----------------------------------------------------------------------LIEDIDTAPLPAPRCPNGKYRFHIRVRSAELAQRIKLNAVKVGASPAMRLEGSKIMPMR------------------------------------------------------------NLLPSGRVLKRVSASINPVNMALKPVVINSVVTTTSSSTTASSPTGALSVLSNSKLLGARSQINAPTPAKVAKTMQDGKPFFYLTPATNSGAAGARLTLTSKTTASASTTTSRTTVTASTTSGQQLIRDPIVKDLATHV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSTVQKQSIANGKTEPEEETEAEDPYKVQELIQMRKEQRLAALKRMAMINRRRTDATPIYGEDCREAIQRCMQATRSLKRSTWQTRGYANCCTAMAHRNGWSLN---------HLLKSFEERCADLKPVFANFVIYVPSVCAPRIRRYVQNLSSTHWQHEQRIENIVDQALRPKLALLHPIISEMTTKFPDPRLIQYDCGKLQTMDRLLRQLKVNGHRVLIFTQMTKMLDVLEAFLNYHGHIYLRLDGSTRVEQRQILMERFNGDKRIFCFILSTRSGGVGINLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVSERTIEVNILKKANQKRMLSDMAIEGGNFTTTYFKSSTIKDLFTMEQSEQDESSQEKSENKDRIVATTTLSDTPSTVVETEKQSLRAFEHALAAAEDEQDVQATKTAKAEVAADLAEFDENIPIATEDPNAEG-----GPQVELSKADLEMQNLVKQLSPIERYAMRFVEETGAAWTAEQLRAAEAELEAQKREWEANRLAAMHKEEELLKQETEAEEMLTYSRKDSSNQVWISRNTMEQMPMWCPPTPPQDNDNDIYIDYS------LSFMYELEPIAETDLPPVYVRKEHKRSRTDAGYDGSRRPNKMRREDNYVPPRSLFDRPTPQLARLRRELKSQRFRGSFKPNMPIPGLKPQLPTKPLTEPEAMAEWCVFEDMAILHVLVN----------------LQGLPCSLMLLSPGQTPNWDLVSEMVNFCSKTYRSARQCRWR----------------------------------------------------------------------YETHIQPREEGKVVESPKKQKKLKPTLRTEYLKSPLRYLRTTQLYVSDNNASFYKTMRSRFDSIKTAYLKKAPPPKRQFSAPSLMNPKHMEVLQEFGILNYDQPVSPQNIAAMKANKIREKQRGQQMSQPPVGVGVVQQMQQQSQQQQQPAPPPLPQQQQPQQVVQQVQQQQQQQQQQQQQQVVQQQLPTVSNVQQTLPVQQTVELVQQQPTTTTTVAVPAAGGQLQQLQIQHLTSSNVSPGQQTAILLHQPQQQLRTHPGQGGQSNTQQLVKTIVGTSSSLTAGQLQQLAQQSAVASGGQSSVSVVLTTPVQTLPSVVQPQIGSGAQIVSISSQTLPVNSSPQLGSIVQTQSLPQVVSVSTLPTVGTVLTTTANQPQQQHQTTAVTTLNTTMLRGQRIVSTAAGNTLQQRTTAGGQSIVSMPNLGQGASPSQFQTQLRLAAVPTSPATQTTQLVTTKGIPVSALQQGGKTTVIPVTQQSGGAHIQLYRQRSLKVLQTTTQAVPSGSAGATGATANLVQAGGTIIQASNMATHVTSQKVAVSGMPGTSTTVQAGNVVSSVQMHGQARTQFIKQMAAGKQQLQRQVVSADGTTTTTAAGDMLLVKRHNILAAQKAQQASGALFTTTTGQQQQQQQQQGQLPVAGQPQQVTQHQIASLVKASTAAAASGSSVNAGGVTVSATNPTVQAGSVNMTLPQLKPGSQIKVTMPNQMRHLQMQQQLTMPRKISRMTQLVSASGQPTATNIITTTGPQQQQQGVTVSGGGTLPTVASQQQQQQHQQKVGGGNSVQAQLLHIQNTKG-----------------------------------------------------------------------------LSNSVTMQQIQQVMRSGQQGTLATTNLVLGKTSVGRVIPVSVASQANQRQTIQVVSAASAQALAAGNLRTHVAGPSIASTLKVAAPGSAGGQTTQQTLIAALQHNQRQNASPVRLQTTAGGNLLAVVQQQQQQQHTSIAGPTAGPAEVMTITQTTTTLPTVGSLQQQQQQQQQQGGISQPTTQQVRKLVQKKILIRSEKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . : . . . . . . : : : :: :. :. . : : * *:* :: :: * .. : : *:* :*: ::.:. :* : :: : : :* .: *: *. .** . :: . *: :: . :*. :: :: : : : : : * .. ..:.:: : :: * .* . ::. .. . : : : ..*: .. : : : .. :..: : * . . . .. . : :. : .: . :::: . .. . *. :.* : * .*:* **: ** **: **:**.:: :.: *****************:***:*** * *******:**:**:******:*::.*.**:*****: ::** ** **.**:******.**:**:**:::*:** *:*::****:*****:* *** ****.::************.* *****::**** .. . : *::**..*: :** . ::. : : :**:*:**:****:* :****** ****:: *:**:*** **:***::: *: ** :*:::*::* ************:*: ** :.* : . .:* *: . : . : :: . : .. . .. : : :. : :.. : *::* : : : : * :: * . *.. : : . : . ** : :: *** *:***.****.: **::** :***.*******::***** **.***::*:****:*::*:** * :*** * ** ****:****:*:********:********:** *.*****************::**:*:* ********** *.::.*: *:*** :*.. ::::*: * . :. :*: *. ****:*: *:. * * : :*:*. : . : : .. .: : :: . * ", "identical_positions": 349, "similar_positions": 334, "identity": "7.61%" }, { "cls_id": "homologset.agr.MGI:2444047", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY02-1", "uniprot_id": "D3ZY02_RAT", "id": "D3ZY02-1", "name": "Protein-glucosylgalactosylhydroxylysine glucosidase", "aln": "---------------------------------------------------------------------------------------------------------------------------MDCSEDDPTRFSADCLPSDPRLWATVTNSYLGTRI----YHDTIHINGVYNGAGGDTHR-----------------------------------------AILPSPLNVHLEAP----------AGT-EQLTETFTLDTNTGSF--LHTLESSSFRASQCIYAHRVLPHVLVFSVSIARLTTGNEPIT-------VPLRADFSPESPDLDLHVGPDFQG-LRYLHGHTLIPEHP--GEPRPEVHMLWVP---VPPALTLGEDEKDRTWEFVTVVGSS------------------------QAEAQGCYAEALQLQTRG---VLYTIHADTWGQLWA-GCGLDVAG-PLALRQALRGSLYYLFSELP---KPGTQGSTSHGLSPGGLSNGSQEECYWGHIFWDQDLWMFPNILMFHPEAARAILEYRIRTLGGALKNAQNLGYQGAKFAWESAGTGLEVCP--EDIYGTQEIHINGAVVLAFQLYYYY--TQDLQLFQEDGGWDVVSSVAEFWCSRVEWSSQDKMYHLKGVMPPDEYHSGVNNSVYTNVLVQNSLHFAAALAEDLGLPVPK---QWLEVADRIKVPFDSEQNFHPEFDGYERGEEVKQADVVLLGYPVPFPLRPDIRRK---NLETYEAVTSPRGPAMTWSMFAVGWMELKDP-SRAQVHLNRSFAN-VTEPFKVWTENANG--------SGAVNFLTGMGGFLQAALFGCTGFRITAAGV----------TFDPLCPDLVS-KVSVSGVSYLGNKLNFAFSKDLVTLEVTARAEPGAPLLEAELWPSLARLTLSPGQK----------------------------VSFPHTAGRIQRSTSIAAQKFI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BP56-1", "uniprot_id": "PGGHG_MOUSE", "id": "Q8BP56-1", "name": "Protein-glucosylgalactosylhydroxylysine glucosidase", "aln": "---------------------------------------------------------------------------------------------------------------------------MDGSEDDPTIFSARCLPSDPRLWATVTNSYLGTRV----YHDTIHINGVYNGAVGDTHR-----------------------------------------ASLPSPLNVQLEAP----------AGT-EQLTETFTLDTNTGSF--LHTLEGPSFRASQRIYAHRVLPHVLVFSVSIARLTTGNKPIT-------VPLRADFSPESPDLDLRVGPDFQG-LRYLHGHVLNPEQP--GEPQQEVHMLWMP---VPPALTLGEEEKDRTWEFLTVVGSS------------------------QAEAQDCFAEALQLQTRG---VLYTIHADSWGRLWA-GCGLDVAG-PLALRQALRGSLYYLFSELP---QPGTQGFISHGLSPGGLSNGSKEECYWGHIFWDQDIWMFPNILMFHPEAARAILEYRVRTLGGALKNGQNLGYQGAKFAWESASTGLEVCP--EDIYGTQEIHINGAVALAFQLYYYY--TQDSKLFQEDGGWDVVSSVAEFWCSRVEWSSQDKMYHLKGVMPPDEYHSGVNNSVYTNVLVQNSLHFAAALAKDLGLPIRK---QWLEVADRIKIPFDSEQNFHPEFDGYERGEEVKQADVVLLGYPVPFPLTPDIRRK---NLETYEAVTSPQGPAMTWSMFAVGWMELRDP-SRAQVHLSRSFAN-VTEPFKVWTENADG--------SGAVNFLTGMGGFLQAALFGCTGFRITEAGV----------TFDPLCPDLVS-RVSVSGISYLGNKINFAFSKDSVTLEVTARAEPWAPLLEAELWPSLAHLPLTPGQK----------------------------VSFPHSAGRIQRSSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32M88-1", "uniprot_id": "PGGHG_HUMAN", "id": "Q32M88-1", "name": "Protein-glucosylgalactosylhydroxylysine glucosidase", "aln": "---------------------------------------------------------------------------------------------------------------------------MEDAGEDPTTFAAHSLPSDPRLLATVTNAYLGTRV----FHDTLHVSGVYNGAGGDTHR-----------------------------------------AMLPSPLNVRLEAP----------AGMGEQLTETFALDTNTGSF--LHTLEGPRFRASQCIYAHRTLPHVLAFRVSIARLAPGSGPIT-------LLLRSAFSPESPDLDLHQGPDFQG-ARYLYGHTLTPEQP--GGPQQEVHMLWTP---APPDLTLGEGEEARTWDFLTAVGGS------------------------QAEAQACLTEALQLQARG---ALYTAHAQAWAQLWV-ECGLDVVG-PLQLRQALRGSLYYLLSALP---QPKAPGYICHGLSPGGLSNGSREECYWGHVFWDQDLWMFPSILMFHPEAARAILEYRIRTLDGALENAQNLGYQGAKFAWESADSGLEVCP--EDIYGVQEVHVNGAVVLAFELYYHT--TQDLQLFREAGGWDVVRAVAEFWCSRVEWSPREEKYHLRGVMSPDEYHSGVNNSVYTNVLVQNSLRFAAALAQDLGLPIPS---QWLAVADKIKVPFDVEQNFHPEFDGYEPGEVVKQADVVLLGYPVPFSLSPDVRRK---NLEIYEAVTSPQGPAMTWSMFAVGWMELKDA-VRARGLLDRSFAN-MAEPFKVWTENADG--------SGAVNFLTGMGGFLQAVVFGCTGFRVTRAGV----------TFDPVCLSGIS-RVSVSGIFYQGNKLNFSFSEDSVTVEVTARAGPWAPHLEAELWPSQSRLSLLPGHK----------------------------VSFPRSAGRIQMSPPKLPGSSSSEFPGRTFSDVRDPLQSPLWVTLGSSSPTESLTVDPASE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0JMP0-1", "uniprot_id": "PGGHG_DANRE", "id": "A0JMP0-1", "name": "Protein-glucosylgalactosylhydroxylysine glucosidase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGVYNGDGGTCHR-----------------------------------------GNIPCPLAAQMKTG----------EVG----RQLYELNMHTGVF--SHTVVTSDFEAIQVLYAHRNQSNLLVMEILLKRIKTSAEPIT-------IQLESSFKPQSEDIAFQNAPDYKG-GRHIFGQTASSEVP--GGVRPVVHLIWTP---VTPTLTLPANQSQSSWTFLVAVARS------------------------NESAQSFYDSGLALINTG---DLRPSHQRSWAELWK-GSSIEVIG-AESLNRALIGCMFYLLGSFPYVNKEASAAFEFGGVSPGGLSNGSEDEDYHGHVFWDQDTWMYPSIALFYPALARAVLQYRVETLEGAQVNAQQMGCKGLKFAWESAVTGVDVCP--EDVYSQQELHINGDVILAFQQYYYL--TQDLELFQSGRGSEVVWGVADFWVSRVTWDSADQQYHIKGVIPPDEYYFTVDNSVFTNAVAQRSLEFAVELSALLAEVPPP---AWQDIADKIKIPFDPELKFHPEFDGYKPGNKVKQADVVLLGFPLAFPMSPEIRRN---DLEMYEAVTDPLGPAMTWGMFALGWLELGEA-EKAQKLLQKCFKN-VQKPFQVWSESADG--------SGCVNFLTGMGGFLQAVLFGYTGFRVQKEQL----------AFSPLLPLDVS-ALSVKGVCYLGHKMDWTITSEEVKVSVRKTDSKETFTLQVVLN-SGSTLLLTPGQS----------------------------VSFPRQPGHICQLKSSSSCWPI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKD9-1", "uniprot_id": "Q9VKD9_DROME", "id": "Q9VKD9-1", "name": "Glycoside hydrolase family 65 central catalytic domain-containing protein", "aln": "-----------------------------------------------------------------------------------------------------------MRKSIVFIGLIALFQSCLAETPETYLLKTHSLPSDLNFMPTLGNGHVGYTI----FGDAIFMNGVYNGAGGNSKR-----------------------------------------ARIPNWINISTEACDRFGCA----TDSDVVNGTSYEMNLRDGYFRVVTTYRGLGISVEQRTYPHKYYNRALVYEVVANRLAGRNSRINSPKFLRLTQFAGNFSDAFDFVVVNNGSSASGNYRTLRGQTKVVENEQFQPDPQEIFVLFSESLEQPLELQWPTWQDQLSHRVIIAIDRD------------------------ESVTRKELQDVLQLSSD----NLLQKHSQSWNSFWDDEFSIEIKGDALELSQIVNAGIFYIVSSLP-SLETNQKNELFYGLSPTGLGRGNLEADYQGHNFWDTEIWMLPIVSLFGLDYAKEVLGYRSRKLEAAKYHANATGYKGARFPWESAYTGTEVTNPCCPEVAEQEIHISPDISFALQKFFAQ--SND-SEWTCGTAWPITADVADFLVSRATCDDSTKTCHLLNVMGPDEDHPNVNDNVYTNAVSKIALNFAEWLAKHCGNASTERLEKWREVSDGLVILRDESLNYHPEYAGYVRDTIIKQADTILLGYPLNFDKS-STHIN---DLRFYANVTRESGPAMTWSMFAANYLRNLQL-TLANEYFERGYKSYVRPEFKVWSETPIGY-------DGSANFLTGIGGFLQALIFGYGGLDFGRTDD----------DQFLMFFGISL-TPPNVEEVFINSIPYGQHAKCTLRFKSRHSEISCYDRIGKGFKMAQGQKRTILGRS----------------------------FNLTRQNEDPPIEISFLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48016-1", "uniprot_id": "ATH1_YEAST", "id": "P48016-1", "name": "Periplasmic acid trehalase ATH1", "aln": "MKRIRSLWFNAEASYSNLNNSPSLRNKNSTGNNSRSKNYRSFSRFDLINSILLLMMLFLLAIFVTALYLTKSSRLTYSHASRAALFNPLGVISPSLGNHTLNYDPEARESSKKLYELLSDFNTAYYDDENMILGSNLFSKNTYSRQPYVANGYIGSRIPNIGFGYALDTLNFYTDAPGALNNGWPLRNHRFAGAFVSDFYCLQPKLNSTNFPELDDVGYSTVISSIPQWTNLQFSLVNDSKWFNPQNVTLDDVTNYSQNLSMKDGIVTTELDWLNSQIHVKSEIWAHRHIHPLGVVSLEIS-LNTDHLPSDFDSLDVNIWDILDFNTSHRTVLHSTGTDEKNNAVFMIVQPDNVPSS--NCAIYSTCTVKYENSTNPINSSESFEEKDVSSNIYNVILTEDQPKIIVHKYVGIMSTEFNKNKEQQDNTNIGLAKMIALNSKGNYEKLLSSHKRAWYDLYN-DAFIEIPS-DSLLEMTARSSLFHLLANTR---DYNVSSDRGLPVGVSGLSSDS----YGGMVFWDADIWMEPALLPFFPNVAQNMNNYRNATHSQAKLNAEKYGYPGAIYPWTSGKYANCTST---GPCVDYEYHINVDVAMASFSIYLNGHEGIDDEYLRYTTWPIIKNAAQFFTAYVKYNSSLGLYETYNLTDPDEFANHINNGAFTNAGIKTLLKWATDIGNHLGEVVDP---KWSEISKDIYIPRSSS-NITLEYSGMNSSVEIKQADVTLMVYPLGYINDESILNNAIKDLYYYSERQSASGPAMTYPVFVAAAAGLLNHGSSSQSYLYKSVLPYLRAPFAQFSEQSDDNFLTNGLTQPAFPFLTANGGFLQSILFGLTGIRYSYEVDPDTKKINRLLRFNPIELPLLPGGIAIRNFKYMNQVLDIIIDDHNGTIVHKSGDVPIHIKIPNRSLIHDQDINFYNGSENERKPNLERRDVDRVGDPMRMDRYGTYYLLKPKQELTVQLFKPGLNARNNIAENKQITNLTAGVPGDVAFSALDGNNYTHWQPLDKIHRAKLLIDLGEYNEKEITKGMILWGQRPAKNISISILPHSEKVENLFANVTEIMQNSGNDQLLNETIGQLLDNAGIPVENVIDFDGIEQEDDESLDDVQALLHWKKEDLAKLIEQIPRLNFLKRKFVKILDNVPVSPSEPYYEASRNQSLIEILPSNRTTFTIDYDKLQVGDKGNTDWRKTRYIVVAVQGVYDDYDDDNKGATIKEIVLND", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*.. * :. . :* . :. . * . : . . :.*: . : : *. : ... .. : : : . :. : . .: . : :. . : * * * :* :: ::: . * . ::::.. . :. **. .. * * *** : ** * : * *: : ** . * :.: * * :.* *. . . * *:. : :* : . : : .*:* : . . . .: *** :::..:**. : *.:* :. . * ::. : : . . : *: * . :****. *: :*: : . : :* * *****: :*. : :. : : : * ::* . . . . ***. *****: :** *: : . : . . . : * . . .: . ", "identical_positions": 73, "similar_positions": 157, "identity": "5.93%" }, { "cls_id": "homologset.agr.MGI:2444049", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6W3F0-1", "uniprot_id": "P4HA3_MOUSE", "id": "Q6W3F0-1", "name": "Prolyl 4-hydroxylase subunit alpha-3", "aln": "-------MGPGARLA-LLALLALG-GDPAAATGREDTFSALTSVARALAPERRLLGTLRRYLRGEEARLRDLTRFYDKVLSLHE------DLKIPVVNPLLAFTVIKRLQSDWRNVVHS-----LEATENIRALKDGYEKVEQDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKVAYDTGDYYHAIPWLEEAVSLFRRAHGEWKT------EDEASLEDALDYLAFACFQVGNVSCALSLSREFLVYSPDNKR----MARNVLKYERLLAENGHQMAAETAIQRPNVPHLQTRDTYEGLCQTLGSQPTHYQIPSLYCSYETNSSPYLLLQPARKEVVHLRPLIALYHDFVSDEEAQKIRELA-EPWLQRSV---VASGEK---QLQVEYRISKSAWLKDTVDPMLVTLDHRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRM------KSGNRVATFMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNL---HRSGEGDGDTLHAGCPVLVGDKW-VANKWIHEYGQEFRRPCSTNPED---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6W3E9-1", "uniprot_id": "P4HA3_RAT", "id": "Q6W3E9-1", "name": "Prolyl 4-hydroxylase subunit alpha-3", "aln": "-------MGPGARLAALLVLLKLGVGDPAAAAGREDTFSALTSVARALAPERRLLGTLRRYLRGEEARLRDLTRFYDKVLSLHE------DLKIPVVNPLLVFTLIKRLPSDWRNVVHS-----LEATENIRAPKDGYEKVEQDLPAFEDLEGAARALMRLQDAYMLNVKGLAQGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKVAYDTGDYYHAIPWLEEAVSLFRRSYGEWKT------EDEASLEDALDYLAFACYQVGNVSCALSLSREFLVYSPDNKR----MARNVLKYERLLAENGHLMAAETAIQRPNVPHLQTRDTYEGLCQTLGSQPTHYQIPSLYCSYETNSSPYLLLQPARKEVIHLRPLVALYHDFVSDEEAQKIRELA-EPWLQRSV---VASGEK---QLQVEYRISKSAWLKDTVDPVLVTLDRRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYKM------KSGNRAATLMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNL---HRSGEGDDDTLHAGCPVLVGDKW-VANKWIHEYGQEFRRPCDTNPED---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z4N8-1", "uniprot_id": "P4HA3_HUMAN", "id": "Q7Z4N8-1", "name": "Prolyl 4-hydroxylase subunit alpha-3", "aln": "-------MGPGARLAALLAVLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHE------DSTTPVANPLLAFTLIKRLQSDWRNVVHS-----LEASENIRALKDGYEKVEQDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKT------EDEASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPDNKR----MARNVLKYERLLAESPNHVVAEAVIQRPNIPHLQTRDTYEGLCQTLGSQPTLYQIPSLYCSYETNSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELA-EPWLQRSV---VASGEK---QLQVEYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRM------KSGNRVATFMIYLSSVEAGGATAFIYANLSVPVVRNAALFWWNL---HRSGEGDSDTLHAGCPVLVGDKW-VANKWIHEYGQEFRRPCSSSPED---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T7S6-1", "uniprot_id": "A0A8N7T7S6_DANRE", "id": "A0A8N7T7S6-1", "name": "Prolyl 4-hydroxylase subunit alpha-3", "aln": "-------MCSCFTLFIVLYLLNMP------DESFGEMFTSMLSVNQAVSAERKLIDHLIIYIEHEAQRLEDIKRFFSRVTSLHDGIYN--EPSDPIANPIAAFKLVKRLKSEWLNVVHS-----TEAEENIKVLREDYRRMESSLPKLEDLRGAAHGLMRLQDVYNLHVESLVRGHFQQISDP--VDFYKLSVSDMLSGDDCFLVGKVAYDLEDYYHSVLWFEEAVRLFRG--TEWSP------ENEGTLEDALDHLAFSHFKTGNISHALSLSRELLLHDPMNRR----VHFNVEKYEKLLNENLPATSSGLTLKRPDGIYLRTRNAYEQLCQTKGSQPKHFENPSLFCDYFTNGSPALFLQPIRREIISLQPYVVLFHGFVTQAEAKNIRKYA-MPGLRRSV---VASGMN---QATAEYRISKSAWLKESAHEVVGKLDQRITLVTGLNVQPPYAEYLQVVNYGIGGHYEPHFDHATSDSSPLYRL------KTGNRVATIMIYLSPVQAGGSTAFIYANFSVPVVQNAALFWWNL---HKNGQGNVDTLHAGCPVIVGNKW-VANKWVHEYEQEFRRRCSLNPEE---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA65-1", "uniprot_id": "Q9VA65_DROME", "id": "Q9VA65-1", "name": "procollagen-proline 4-dioxygenase", "aln": "---------MLLAKCVLFLVLQVL-------SCHGEFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIRVEHLNAAD--GIDDYLNNPVNAFRLIKRLHSDWETFEGS-VTADSSRSNYLDTMASLKENLSFP--SQDDFVGSAIALTRLQQTYQLDVAELASGILN-----------GVKYGTAMSWQDCFVLGQHLYALRDYNHTVPWLQQSMQLLGEQS----------YGSESASLDFMEAVVEYHREMGAHESALSLVNHVLSIEPDQRS--HLLEARQQLEELITDGDKNGLLHLTARRPGDYHESREFRMYEQVCRGE-LAPLPSKQRNLRCRLRKSRLGY---APFKLEELHLDPLVVQLHQVIGSKDSDSLQKTA-RPRIKRST---VYSLGGNGGSTAAAFRTSQGASFNYSRNAATKLLSRHVGDFSGLNMD--YAEDLQVANYGIGGHYEPHWDSFPENHIYQEGD------LHGNRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNL---HPSGDQDFRTKHAACPVLQGSKW-IANVWIRERNQDNVRPCDLERGQEISLHYRDFD-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA64-1", "uniprot_id": "Q9VA64_DROME", "id": "Q9VA64-1", "name": "procollagen-proline 4-dioxygenase", "aln": "------MRGLVLLVGLIFLLAQG--------SLASDYFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHTMAAS--DTENYLTNPVNVYRLMKRLHTDWSLMEGR-VQLMAEEMNFN---ATREYGLSYP--SQEDVEGAALALVRLQSTYKLDVAQVAQGILN-----------GVKYGSDMSWQDCFELGQQLFEMEDYNNTKVWLRESMERLRRQTSHAPSHLAPTSGPDTVTLNKMEATAKSLFQLGDFDTAFELSQRVLQFDPKRIRNWHLGDKGTAPPEDIDD-------VYLPKHSDSYSLSQEFAKYEKVCRGE-VHPIVR--QELRCRYSRGNHPYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREMA-VPRMHRST---VNPLPG-GQLKKSAFRVSKNAWLAYESHPTMVGMLRDLKDATGLDTT--FCEQLQVANYGVGGHYEPHWDFFRDPNHYPAE--------EGNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNL---HRSLDKDYRTKHAGCPVLKGSKW-IGNVWIHEVTQTFARPCDVFRDHEVSLEYEIIK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7H5-1", "uniprot_id": "Q9I7H5_DROME", "id": "Q9I7H5-1", "name": "procollagen-proline 4-dioxygenase", "aln": "-----MLDRHCLYIGIFQLIIWVG-------VANGEFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKREHEWATSQLKLDDYLGHPLHAFRLIKRLVRDWDSLIFEPILANNAREEFRAFVEVLSRDLGYP--DQSELQGAIKGLARLQKVYNLATSDLADGIIG-----------GLNYGSDLRWRECYEIGVQLFDLGEYQRSLEWLQVAFILLRNSPREE-------KDADHYLSDIREYASMANFELGNPKKAARLLSQILESQPTHSA--QQTQKYLESRVPGKN--------------VQETKPSWFSNYTRLCQGR-RLPEERSGDPLRCYLDGKRHAYFTLAPLQVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSA---VAGSGG--EGTVRDLRVSQQTWLDYKS-PVMNSVGRIIQFVSGFDMA--GAEHMQVANYGVGGQYEPHPDYFEVN--LPKN-------FEGDRISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNL---HRSLHVDARTLHAGCPVIVGSKR-IGNIWMHSGYQEFRRPCNLTSDSYKSLAYRD-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA63-1", "uniprot_id": "Q9VA63_DROME", "id": "Q9VA63-1", "name": "procollagen-proline 4-dioxygenase", "aln": "----------MFRLSIILSLLCVF-------PVNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQID---EQQNDRGDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKINFKGPTQEDLHGATRALLRLQNMYQLNTDHLASGVLHP--------GEKNALGTSLSASDCFELGKNLCEIKEYSYGSEWLLEARKRLHGKPLGF-------ISPNVSDVEILEHLSSAFNGLGNLKLAYKLNNEILDKKPDHEE--ALKNKILYEGQLARERSFAPRKQVELPQIAEKEQKESYKLYTQVCRGE-LHQSPREQRNLRCWLYHQGVPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHG-KGNMERSK---VGQSE---NSTTSEVRISRNTWLWYDANPWLSKIKQRLEDVTGLSTE--SAEPLQLVNYGIGGQYEPHFDFVEDDGQSVFS-------WKGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNL---HSSTHKDFRTKHAGCPVLQGSKW-ICNEWFHVGAQEFRRPCGLSSDEGKFLHLKDI------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVQ7-1", "uniprot_id": "Q9VVQ7_DROME", "id": "Q9VVQ7-1", "name": "Prolyl 4-hydroxylase alpha subunit domain-containing protein", "aln": "--------------------MGDNSGESEYVENNSVYSSITR-LLKLLEMEEIFITNIKAYTNKLAEKVKNLQAYIDSVDYEFQQSFE--DREKYVGNPINAFSLVRRTHQDLPKWHNYSQ------QIVGMEELFALEEIIAKVPDKKDMAYSLGEMHRIEQIYDLEAIELARGRIQGK-----------QYDFRPSIRDCVALGEHKFKREDYQRASMWFRVAIKHEPEGNAEIIN---------SILGDPKVNLYTLYAKSMLIFGMIKSNPSMT---IAEAKKISYEALNKASLADIKSLLNELLSQTDDEIVYEMNVNKTKP-SDYEIGCRGQFL---RRRNHVCTYNFTITEFLKLAPLKQEVLNWDPYIVIYHDVLNDDEIDKLKN------------------HLNDTDAVEVNP-------------IEKRIFQRINELTRLSFEH--SDQQIVSKNGPRTHKHKKEYLKG----------------------TLLFFLNNVELGGAMVFPKLKISVFPQKGSCLFWHNT---LDP-----RSEPLECPVLQGNKR-VITQKGAYNGRPMQYKKAKSNQKF--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQS7-1", "uniprot_id": "Q8IQS7_DROME", "id": "Q8IQS7-1", "name": "procollagen-proline 4-dioxygenase", "aln": "----MRKYHSLLPVLLGFAVLNSFVGCVEDIEEKERYSSSTVGLLKLLKVEEKFTDNLLNQVDQLGEKFEALRMYLSSVGYELHRSLN--EKVQYVSNPINAFSLLRRTHEDLPKWHEYFK------EAIGEGNQSILVDLVKMVPNDVDMLSAMHGIQRIEKIYDLKIDDLAQGVLQGV-----------QYNVQLTYRDLIAMGNSMYQQSDYQTAAKWYRIACKRELENPEQLFI---------QILGDPSEHLHRQYIKSLFKYGSTTSEPSKS---IEEAFIMVQASQ--EELDNIMSDLNE--PQNDVEVEKDLYQVKRSP-SNCELGCRGLYR---QKTNLVCRYKSTANTFLRLAPLKLEEISLDPFMAMYHEVLYDSEIRELKGQSMN----------MVNGYASQRNGTEIRDTVVRYDWWSNTSLVRERINQRIIDMTGFNFLK--DEKLQIANYGLGTYFQPHFDYSSDGFETP----NIT-TL-GDRLASILFYASEVPQGGATVFPEINVTVFPQKGSMLYWFNL---HDDGKPDIRSLHSVCPVLNGDRW-TLTKWVPMFPQMFSFP-CKS------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVQ6-1", "uniprot_id": "Q9VVQ6_DROME", "id": "Q9VVQ6-1", "name": "procollagen-proline 4-dioxygenase", "aln": "------MLNVVRAAAVLILVQSIHSTDPNDFLNRKYYSSSVLGLVKLLKMEQEFMVNFSIYANILQEKVDNLNIFLDALKRPNHKTHN--EREKFVSNPLNAFGLIRRLNQDWPKLQNYTQ------KPLGLEQLTAMQDIVSAAPESFDMNEKLKAMHRIETTYDLQPKDIAKGLLQRT-----------EFNYRLLFRDCLALAYHKFEIGEFKRSLLWFQEALKLSTDGSLEIMN---------RLK----EIELKGFATAVAKRSIYLSNQGLT---NETIDDMANSQLQDAKLMDLEQLISS-------ELKQWINDDSTTPPTDHNLGCRGLFP---KKSNLVCRYNSSTNAFLKLAPLKMEEISRDPYIVMFHEVISDKDIEEMKGEITE----------MENGWTSLGDPKEIVS---RVYWIRKESSFSKRINQRISDMTGFKLEE--FPAIQLANFGVGGYFKPHYDFYTDRLKEV----DVNNTL-GDRIGSIIFYAGEVSQGGQTVFPDLKVAVEPKKGNALFWFNA---FDDSTPDPRSLHSVCPVLVGSRW-TITKWLHYAPQLFVKPCSPRVHLE--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVQ9-1", "uniprot_id": "Q9VVQ9_DROME", "id": "Q9VVQ9-1", "name": "procollagen-proline 4-dioxygenase", "aln": "----------------------------------MIYSTSVMSMMKLLEMEESLKTNLDIYVQEMQSKLDLIKLYQDSLKRVTLTTLE--EKEEYVSNPLNAFPMLRRLNQDWPKWLRYIK------LAIASKKIKEMEVQLKSAPIDDDLKVALKGMTRIEKFHNLHAEDLTKGVLMGK-----------KLNSHLTAPDCVALGDYYYNQTQFSGSTHWYRMALRVHTHPRGMIYA---------KVLGLKRKRIYKKYAKALLKESLNSDKSKPTPTEKSEWNRLAKEVTREDNYDNVKKLIDEYLSGDEKIFQEVAARLKRKP-TKLERGCRGEWPKK-SSPELICRYNRDTSAFLKLAPLKLEFLSVQPMILLYHDVLYENEFKSMRDIAMYNGSMIDGW--TYVDFDKKGNPKQQDRVVKMIAFQGTTAPFTLSINRRMADMSGLEMRD--NMVLYLTNYGLGGHFGKHVDYVELAKRPP----DFFADFGGDRIATALIYASDIPLGGTTVFTKLKIAVQPKKGSALIWFNL---NHAGEPDPLTEHSVCPVVLGSRW-IISKWIHERQQVFKKPCLA-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8DYR4-1", "uniprot_id": "A8DYR4_DROME", "id": "A8DYR4-1", "name": "procollagen-proline 4-dioxygenase", "aln": "MLLRSFHYILLNWILLFLFTVCKAKKAENDVVQEVIYSNSIRALSELREIENSYMEHLNNYVSFLQQKIKTLRIFINSLTPNYLDHKV--DRYKYVSNPLNSFGLLRRAHQDWPKLIAYLKD-----QGNIKVDIEEMNKLINRTPHANDMEEALMGMDRIEHFYDLKSSDMAQGLVAGQ-----------QLSSRMSASDCLALADYMYKRSEFRRAAEWYRIALSVFTKPKNNIAF---------KFYAPKRKELEKMFVISRLQEGSVEN-----------LTDCLKELSQDPNNS------------------LVHLRPRKSP-TMIEQGCQGKFP---PGPQLVCRYNSTTTPFMRIAPLKEEEISRDPLIWLYHDVIYDSEIAQLTNVTR--EEMILG---TTTNYT---TPDRVNRLFHIKVTDDDGGKLDKTLVNRMADISGLDVGN--TTTLARINYGLGGYFQEHSDYMDIKLYP-----ELTEE--GDRLMTFLFYMTDVPVGGTTIFPGAQLAIQPKKGSALFWYNL---HNNGDPNLLTRHAVCPTIVGSRW-VLVKSMLNYEQMFKKPCYK-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VHU7-1", "uniprot_id": "Q9VHU7_DROME", "id": "Q9VHU7-1", "name": "procollagen-proline 4-dioxygenase", "aln": "-----MYILKNLTLIGFLSACFINCQGFVKSNPKKSYAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKS--DYESYLGNPLNSFRLIHRLHTSWRKWYQYAIKV----ENNALGHIENARLMRKMLPTSSDLQQACRGIHDLMSFYDLKPEELAAGNLAGYS----------QPGTGLTAYDCLALGEFSVQKREDDLAEAWYNLSLIRFENKFDKYRV---------HKAWGLLLAKNKQLTDAFYHFENKPEGIIAS---------------------------------------NEVIHFKEELSTKQNCAVVVQKP-----SRLHCRYNTTTTPFTRIAPLKMEELGLDPYMVVFHDVIYDTEIDGMLNSSNFG-----------LSLTDSGQKSEVRTS------KDSYIVDAKTLNERVTDMTGFSMEM--SDPFSLINYGLGGHYMLHYDFHEYTNTTR----PKQ----GDRIATVLFYLGEVDSGGATIFPMINITVTPKKGSAVFWYNL---HNSGAMNLKSLHSACPVISGSKY-VLTKWINELPQMFVTPCMKDSNLHPPQKE---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA61-1", "uniprot_id": "Q9VA61_DROME", "id": "Q9VA61-1", "name": "procollagen-proline 4-dioxygenase", "aln": "-------MLFWRLVLLGMLYLSLSFGQLRENNAQQRFARSVVNMDDMLNLEDDLVSNVEKLAEALARKAKTIKWGVFKMMKRRQE-YK--SSMEIFANPIDTFSLIRHMQSNWLMWLLYLE------TPVGQEELFFVDSRMPLLPKYFDFIDAAEGIRKMQATYQMFSSDIAKGLLDGV-----------QYNSSLKPIDCLAIGLHLMNNSRWYAAEQWISASIEAYDQKSSQTDM---------ELLRGPKLADLCRILGQVQMKQRNHEGALQA------YQVALKLSPHDPEIYEEYRILEKRDLTLSDIEPIEQDKDNSHERLVLPPCCSGRCQVPRNLSNLYCVYNHVTSPFLQLAPIKTEILSIDPFVVLLHDMISQKESTLIRTSSKEH-MLPSAT--TDPDASDDETQVDTYRTSKSVWYSSDFNDTTKKITERLGDATGLDMNS--TEFYQVINYGLGGFFETHLDMLLSEKN-------RFN-GTSDRIATTLFYLNEVRQGGGTYFPRLNLTVFPQPGSALFWYNL---DTKGNDHMGSLHTGCPVIVGSKW-VMSKWINDMGQEFTRPCVESSLSSNEVLSAERLII---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IMI2-1", "uniprot_id": "Q8IMI2_DROME", "id": "Q8IMI2-1", "name": "procollagen-proline 4-dioxygenase", "aln": "-------MPVLKLLFVVIFFLSLSMGQIEAT--QPRFARSVVNMDDLLNMEDDLVSKLEGYAEKLSYKANTIRWGIQQMREQLD---K--SKKEQSFDLFNRYSFIRHMQADWLMWKQYLD------KPVIRDELNYKQMDNLRMPQELDLFDASEAIRRMQATYAMLSNDIAEGFLDGV-----------QYTSKLSPIDCLAMGRHLMNQSRWTIAEQWILAGIKAQDRKGPQTEM---------ILLRGPTKAELFRTLGKVRFERRNEEGALKA------YQAALKHSPHDLEIFQEYQNLKRRVLTLSPSEPIREEPNDDIEEMELPPCCSGRCEGPRKLNRLYCVYNCVTAPFLRLAPIKTEILSVDPFVILLHDMVSHKEGALIRSSSKNQ-ILPSET--VN---AANEFEIAKFRTSKSVWFDSDANEATLKLTQRLGEATGLDMKH--SEPFQVINYGIGGVFESHFDTSLADED-------RFVNGYIDRLATTLFYLNDVPQGGATHFPGLNITVFPKFGTVLMWYNL---HTEGMLHVRTMHTGCPVIVGSKW-VVSKWIDDKGQEFRRPCLRSRLDSKYLSSIEKIII---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA50-1", "uniprot_id": "Q9VA50_DROME", "id": "Q9VA50-1", "name": "procollagen-proline 4-dioxygenase", "aln": "------MGYFIRCLLVMLFHSTLVLG---HRPLEKSHSLSLVTMVPLLELEKKLIDNLENYTNALEQKLEIIRSQLLVIRAENEKGRR--NAISYLSNPLNGFSIIRRLHQDWINWRKYME------QPVGIWQLKAFYSWKDELPTERDLWDACEGIARIQSTYDLKVGDFINGNINGK-----------QYNDSMSTADILSVGAYLFMKNRPSDAIQWLQEVPQRLQEELLIQPR---------HLP--IKEVDALRLLAEAQIKDQNYSEALPL------LHNCLKLQPHDARVLRLWKKTTDFIENQPDQSPTENKKRNVPIANAFKLSCNGPLESS---TRLHCFYNFTTTPFLRLAPLKTEQIGLDPYVVLYHEVLSAREISMLIGKAAQN-MKNTKI--HK---ERAVPKKNRGRTAKGFWLKKESNELTKRITRRIMDMTGFDLAD--SEGFQVINYGIGGHYFLHMDYFDFASSNHTDTRSRYSIDLGDRIATVLFYLTDVEQGGATVFGDVGYYVSPQAGTAIFWYNL---DTDGNGDPRTRHAACPVIVGSKW-VMTEWIREKRQIFIRPCLPKAKGTSTKS----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0KHY7-1", "uniprot_id": "Q0KHY7_DROME", "id": "Q0KHY7-1", "name": "procollagen-proline 4-dioxygenase", "aln": "-------MPKLLISLAILYLLVLVKSHSKPKILENNYAISIYDMSKLIDYEHYLLNILQKFANALQKRVDTLEYYLEMTDYDREK--------NLAEDPIKHFRITRRLHSDYVNWVWFME------EQPWGTLVKDIIAIAPEMPTLKDVEEAIRGLRLIQWTYSLPTAEMAKGVLQDI-----------HHNTSLDGMQCITIARHMVNYKDFIRAKEWLMVGLKMYEADEEIEYI---------YSQLGMPLVDFYELFVEIQDELGSRYLAMSE------LQLAIKNWPEKVSLQRALSRLKMNIRIGKEPAEKKNKSKR-----VYKKCCSSECRPT---AKLYCLYKTTSSYFLRLAPLKMELLSLDPYMVLFHDVVSDKDIVSIRNLTKGK-LARTVT--VS---KDGNYTEDPDRTTKGTWLVEN-NALIQRLSQLTQDMTNFDIHD--ADPFQVLNYGIGGFYGIHFDFLEDAELD----------NFSDRIATAVFYLSDVPQGGATIFPKLGLSVFPKKGSALLWYNL---DHKGDGDNRTAHSACPTVVGSRW-VMTKWINEREQIFRRPCLTSI-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA60-1", "uniprot_id": "Q9VA60_DROME", "id": "Q9VA60-1", "name": "procollagen-proline 4-dioxygenase", "aln": "------------MIFPVFSVLFLLFHQAIPSVSGVEFFSSIHEMTKVFGYEQKMVLHMQKFLSDNQDKLDFLKARLREFENERNEAREW--GPSYFESPINKYLLNKRLTVDWQRVENLMATS----TGEKPLTRLRKFRNRETMPDKKELEGAIDGLLRLQYVYRLKAKDLARGILDGV-----------DYGTQLNSEHCVDIARLALRDQHPRLAHSWLIEANDRLTGGEKEE-----------QLKPQILALLVQAKKELEDFRGLNDTYQELIGIQSASEEHAKNYETFLNALSEKALLNESKPILEHAPIPEEGEPVGEFQAYSLTCSGHWRLTPK-EQRHLRCGYVTETHPFLWIAPLKAEELFQDPLLVLYHDVIYQSEIDVIRKLTENRLMRATIT--SHN-----ESVVSNVRTSQFTFIPVTAHKVLSTIDQRVADMTNLNMKY--AEDHQFANYGIGGHYGQHMDWFYQTTFDAG---LVSSPEMGNRIATVLFYLSDVAQGGGTAFPQLRTLLKPKKYAAAFWHNL---HASGVGDVRTQHGACPIIAGSKW-VQNRWIRENDQSDRRPCELWDDSLATYAQILELNKQNE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VA52-1", "uniprot_id": "Q9VA52_DROME", "id": "Q9VA52-1", "name": "procollagen-proline 4-dioxygenase", "aln": "---------MSSVVLFAVSFILVLSWIAEGYRDRQNYVISVEEKMDLLEKDRELIIVLDSYATELNEKIIMLKRIVKEFKQPLEKAKN--REEEYLSNPIDSLSLMRQMHEDWEKVEKLLK------KPVGQEKIALVEKMREDLPVENDLMEANQAMFRILHTYDLEPKDVSAGWIDGV-----------QYGGKMSASDCFTMGTFSFMAGSYQIASKWLSAAKDLLVDQPRKYHEVMG------ITKADVTLLLARSLIASGNVSIATDMLMRDFMFGEAGSALTVHFLRNKPKPS-----------------INLESWESDESFNQLCRSSSRRQMGESKPSRLHCRYNTITTPFLKLAPFRMEELSLDPYVIFYHNVLSDAEIEKLKPMGKPFLERAKVFRVEKGSDEIDPSRSADGAWLPHQNIDPDDLEVLNRIGRRIEDMTGLNTRS--GSKMQFLKYGFGGHFVPHYDYFNSKTFSLET--------VGDRIATVLFYLNNVDHGGATVFPKLNLAVPTQKGSALFWHNID--RKSYDYDTRTFHGACPLISGTKL-VMTRWIYELDQMFLIPAVLPPRSRNFSKSLPNPF----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVQ5-1", "uniprot_id": "Q9VVQ5_DROME", "id": "Q9VVQ5-1", "name": "procollagen-proline 4-dioxygenase", "aln": "-------------MFIILSICLISLGPPIGLCEITNSAMSIAGMKELVDLEGFFISEMESYTAALKNKIDLMESLLQEVQSKREISRR--NPEEFVAHPLNAFSLIRRLHEDWTQAELLMLN-----QVGLEHLQAIETGLEEAQPSDNDLNDAIGGIISLQQFYNLQPSDIANGLLMGQ-----------QYNASLTTLNCQALANACMNFNYDKYALNWFKAAVDHYNDDRDGQVYR--------EVFDFRLPDLYINYTSVLVTKGFRKAAWKVLQDVADLDATLWLLRKDIYEVG-------------------KIDVPDPTFIITPWFDVTGCLRVGQTSQHLSCHYEKNTSEFLRIAPLKVETLSLKPHIVLYHDVIYDSEISKVKNIS---------------LPSLKSPLRILYAIDYNLKFAKIREDHQSPLSLRIKDMTGEDVQE--DTDFQIDNYGICGFRNFHTDNIELQDQTAELG---------DRLTSIMFFMNDVAQGGALAFPNLNLTIWPQKGSALVWRNL---DHRMQPNQDLLHVSCPVVVGSKW-TLVKWLHERPQMFSRPCTTGRKFKSHDQSMKFRALNK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IMH8-1", "uniprot_id": "Q8IMH8_DROME", "id": "Q8IMH8-1", "name": "Prolyl 4-hydroxylase N-terminal domain-containing protein", "aln": "----------------------------------------------MLNLERNLLQNMRDYAEKLEEKIDLINNYVEDYNVDIEDANE--DPEKYLSNPLNSFRLIRHMHQDWVGWQVYMED------LVAPEAVQKVESLLPQLPQKEAFRKAARSVHSLTQFYGYEPADLVAKDERSS-------------SLHLSPLDCYHLGLELYEEQDYLGAAKWLQVAAHNYTLSRHRDLFN--------PLGAPRWQVYRDLGRTLLKLNRQCAYDAYESALRLNSQNVHLMKEAGQMELFSLR-------------DPMEPILDLQPKPTVLEKYCRGEVPR--HQGRLTCELNDWVHSFLAYAPIKFEDLQQDPFIILYPGSIYEQEIRHVENAYER---------------CPPNDRFELKLGISGCSISDGYSPVLKRINERILDMAGVEKTW---DTFYIVEYAQLAPFEPFKLFRNSTKFPKLN-----LMNFEDVEAKVIIFLKDVTLGGAFTMPNGDILVQPKRGNVLITFEN----------EEHSTTICPIIEGTGL-VMIKFIMKTDE---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IMI4-1", "uniprot_id": "Q8IMI4_DROME", "id": "Q8IMI4-1", "name": "Prolyl 4-hydroxylase N-terminal domain-containing protein", "aln": "-------MPVVFSVLWLLQLFLLVES-----VAGANFARGEEQLQALLDTETQLIDGLRDYIERLERQLEEIRRETSAIEEIHSQVDS---VEEYMGNPLNVFGILKRFESVWPGLEQKAN------ATLEMVFGERLSDRQLTLPSEEDYEESLNHLLHLQSVYELDSNSLSLGVVNGF-----------KLGSSMSWGDCLEVAR----KSDFPVARFWLESALEKLPSASENSTESQR---ERESGRVHILEATLNIEYRAGELSRALATAEELLLLLPMNQGIQKAKRKIEKAMAKKELPKGR-----GQKSKAKKQISKSTEQLLIEEICRGAKQQVTTGSRFNHCQLDGSSPWLLLQPSRLEPVSSDPYIVLHHDVLTPKESNELLQLID-----------------------EEEDTKGVSYQSLKLSKLAQKKLGRISRLLGLEILE-------LDPWTGRRHGHEHITKLEHSSELK-------------HVARLMLNLQAPGMGGAVVFPQLELAVNVPRGSLLHWRTRFAGGSSSEWDYRSGQAICPVLLGVQLSVIACQSNVLRDTLYGPRGQDSIDVGSEA----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: : : : . . :. * * : * * : : . : . : ** : : ** : * ", "identical_positions": 9, "similar_positions": 21, "identity": "1.49%" }, { "cls_id": "homologset.agr.MGI:2444054", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK71-1", "uniprot_id": "ARL11_RAT", "id": "Q5BK71-1", "name": "ADP-ribosylation factor-like protein 11", "aln": "MGSVNSRGHK--AQVVMLGLDCAGKTTILYKLKGNRLVDTLPTVGFNVEPLEAPGHVSLTLWDIGGQTQLRATWKDYLEGIDLLVYVLDSTDEARLPEAVAELEEVLEDPNMAGVPFLVLANKQEAPDALPLLEIRNRLDLERFQDHCWELRACSALTGQGLQEARQSLLHLLRS---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P3A9-1", "uniprot_id": "ARL11_MOUSE", "id": "Q6P3A9-1", "name": "ADP-ribosylation factor-like protein 11", "aln": "MGSVNSRGHKAEAQVVMMGLDSAGKTTILYKLKGNQLVDTLPTVGFNVEPLEAPGHVSLTLWDIGGQTQLRATWKDYLEGIDLLVYVLDSTDEARLPEAVAELKEVLEDPNMAGVPFLVLANKQEAPGALPLLEIRNRLGLEGFQKHCWELRACSALTGQGLQEALQSLLHLLKSR--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969Q4-1", "uniprot_id": "ARL11_HUMAN", "id": "Q969Q4-1", "name": "ADP-ribosylation factor-like protein 11", "aln": "MGSVNSRGHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPGHVSLTLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGVPFLVLANKQEAPDALPLLKIRNRLSLERFQDHCWELRGCSALTGEGLPEALQSLWSLLKSRSCMCLQARAHGAERGDSKRS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********** *****:***.*****:******::**:************:***********:***: ***:******* *:***************:.*** ***:*******************.*****:*****.** **.******.******:** ** *** **:* ", "identical_positions": 144, "similar_positions": 21, "identity": "73.47%" }, { "cls_id": "homologset.agr.MGI:2444058", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BZ10-1", "uniprot_id": "TM11G_MOUSE", "id": "Q8BZ10-1", "name": "Transmembrane protease serine 11G", "aln": "MYQPGILVRRKRVWKPWTVALITVALLLALAVLIGLLVYFLVYDEKTHYYQASFWIPSINYSSDLSKEQSKFRTGLKQKISNEIDVIFQRSSLKHHYVKSQVVNFRPSNDGVKADVLIKFQIPRKNAGTLKRQADNILQEKLQSSQSILKRDASLPYLREMNAAQAEHILNSDCGSGMEYPPIARIADGKPADKASWPWQSSLQVEGIHLCGASLIGSQWLVTSAHCFDNYKNPKLWTVSFGRTLS-SPLTTRKVESIIVHENYASHKHDDDIAVVKLSSPVLFSENLHRVCLPDATFQVLPKSKVFVTGWGALKANGPFP------NSLQEVEIEIISNDVCNQVNVYGGAISSGMICAGFLTGKLDACEGDSGGPLV-ISDNRNKWYLLGIVSWGIDCGKENKPGIYTRVTHYRDWIKSKTSI--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5QSK2-1", "uniprot_id": "TM11G_RAT", "id": "Q5QSK2-1", "name": "Transmembrane protease serine 11G", "aln": "MYQPGILGRRKRVCKPWTVALTTTAALLALAVLIGLLVYFLVYEEKTHYYQASFWIPSIKYSSDLSEEQSKLQINLKQKINNEIDVIFQRSSLKHHYVKSQVVNFRPSNDGVKADILIKFQIPRKNADTLRSEADSILNKKLQSSQSFLKRDISLPYLREMNAAQAEHILNSNCGLGMEYPRIARIADGKPAGSNSWPWQSSLQVEGIHLCGASLIGSQWLVTSAHCFDNYKNPKLWTVSFGRTLG-NPLTTRKVESIIIHENYAAHKHDDDIAVVKLSSPVLFSENLRTVCLPEATFQVLPKSKVFVTGWGALKANGPFP------NSLQEVEIEIISNDVCNQVNVYGGAISSGMICAGFLTGKLDACEGDSGGPLV-ISDNRNKWYLLGIVSWGIDCGKENKPGIYTRVTHYRNWIKSKTNI--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1ZBU1-1", "uniprot_id": "A1ZBU1_DROME", "id": "A1ZBU1-1", "name": "trypsin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MYSTKFLWWLMALVAYAGATPTPGD----------------GRIVGGEVATIQEFPYQVSVQLQGRHICGGAIIGIDTVLTAAHCFEDPWSSADYTVRVGSSEHESGGHVLSLRRVIAHGDYNPQSHDNDLALLILNGQLNFTEHLQPVPLAALADPPTADTRLQVSGWGFQAEESAVSGEVGVSPQLRFVDVDLVESNQCRRAYSQVLPITRRMICAARPG--RDSCQGDSGGPLVGYAAEEGPARLYGIVSWGLGCANPNFPGVYTNVAAFRSWIDEQLDARGWDELLAGWSRLQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:* :* ..: .: .**..*: * .:*:* *:*::* *:**.::** : ::*:****:: .. :** .* : . . .:. :* * :* .:.**:*:*:: *.. : *:*:*: * *. : ..::: *:*** :.... .*: *:::::..: *.:. .*: ****. *:*:******** : :.. * ******:.*.: * **:**.*: :*.**..: . ", "identical_positions": 77, "similar_positions": 101, "identity": "17.54%" }, { "cls_id": "homologset.agr.MGI:2444060", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXU0-1", "uniprot_id": "D3ZXU0_RAT", "id": "D3ZXU0-1", "name": "", "aln": "MATVINPQMDV--EVEECLIMKVEKDSGWASEPILERSDSTECESFRKCFRQFCYEDVTGPHEAFSKLWELCCRWLKPEMRSKEQILEQLVIEQFLTILPEKIQAWAQRQCPESGEEAVALVVHLEKETRRLRKQVSGPQHSEKQAPPRTVWEVANYEPEQLETQHRVVSREEAGNFHSGHQEQLNQKREHRPLPKNAHSSVWAPVPSSEWTAVDEEATT-------QEPVRDIHTVRSFPYKRSVQQVPAHRDLYHEIRKESACSVVSLGDTVSAPNKIAQLEQKKEPWTVGLHSSNKRTSVLQSKISKEKSVHAVQIPARNAGKVWREQQQWGLEDEKIAGVHWSYEETKTFLAILKESRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHMLEPCAFFEDMDALLNPEAHTSSTERPKAVISLP-LKRTAVSAKEQVSLVEEEEGAEDSDGDEVGIEFVRKSEIRAAPILFQNLSGVHWGYEETKTFLDILQETRFYEALQACHRK-SKLYGVVAEQLRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALVNCRTAALPTNTSEEIPSLSRQERGHIEVEPQEPTTWEPEESSQEAVLEDSGSERMSEEEITEEPEFEGSAGLPQSPTDFEIGNIIKEAPTQVIFKDTESHRALIEKPKRFVSQNTNPSKYGKRECFSGRHWENLQGVRQGKLMSQPRDTGKAVVHQRPFVGRRPYRLLKYGENFGRSARLVCRMTHQKENPYKCGVCGKCFGRSRSLIRHQRIHTGEKPFKCLDCGKSFNDSSNFGAHLRIHTGEKPYRCRECGKCFSQSSSLIIHQRTHTGEKPYQCEECGKSFTNSSHFSAHRRAHTGENPYKCGDCEKSFNNCTRFREHRRIHTGEKPYTCAQCGKHFNKSSFLTKHREIHIREKPLPYSPSVYSPENLLKARSAELRKTF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3X952-1", "uniprot_id": "G3X952_MOUSE", "id": "G3X952-1", "name": "", "aln": "MATVMNPQIDV--EVEECLIMKVEKDSEWVSEPILERSGSTECESFRKCFRQFCYEDVTGPHEAFSKLWELCCRWLKPEMRSKEQILEQLVIEQFLTILPEKIQTWAQKQCPESGEEAVALVVHLEKETRRLRKQVSSPLPSEKQAPPRTVWEVADFEPEQLETQHRVVSLEEAGSLHSGHQEQLNQKREHRPLPKNAHSSVWVPVPSDEWNALDEEVTT-------QEPIRDVHTERSFSYKKSVQQVPAHRGLYHEIRKESAGSMVSLGDSVSAPNKIAQLEQKKEPWSVGLHSSNKRNSVLQSNYIKEKSVHAVQIPARNAGKVWREQQQWGLEDEKIAGVHWSYEETKTFLAILKESRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHMLEPCAFFEDMDALLNPAAHTSSTERPKVVISLP-LKRTAISAKEQVSLVEEEEGAEDSDGDEVGIEFIRKSEIRAAPVLFQNLSGVHWGYEETKTFLDILQETRFYEALQACHRK-SKLYGVVAEQLRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALVNCRPSSLSTNTSEEVPSLSRQERGHIEVEPREPTTWEPVETPQEAVLEDSGSERLSEEEMIEEPELEGPSGLLQSPAGFEIGTIIKEDPTQVMFKDTEPHRVLMEKPKRLVSQNTNPSKYCKREYFSGRHCENLQGVRQGKLMSQPRDTGKAVVHQRPCVGRRPYRLLKYGENFGRSARLVCRMTHQKENPFKCGVCGKCFGRSRSLIRHQRIHTGEKPFKCPDCGKSFNDSSNFGAHQRVHTGEKPYRCRECGKCFSQSSSLIIHQRTHTGEKPYQCEECGKSFTNSSHFSAHRRIHTEENPYKCGDCEKSFNNCARFREHQRIHNGEKPYTCAQCGKHFNKSSFLTKHREVHMREKLLPYSPSVYSPENLLKGKSAELRKTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63HK3-1", "uniprot_id": "ZKSC2_HUMAN", "id": "Q63HK3-1", "name": "Zinc finger protein with KRAB and SCAN domains 2", "aln": "MAVALDSQIDAPLEVEGCLIMKVEKDPEWASEPILEGSDS--SETFRKCFRQFCYEDVTGPHEAFSKLWELCCRWLKPEMRSKEQILELLVIEQFLTILPEKIQAWAQKQCPQSGEEAVALVVHLEKETGRLRQQVSSPVHREKHSPLGAAWEVADFQPEQVETQPRAVSREEPGSLHSGHQEQLNRKRERRPLPKNARPSPWVPALADEWNTLDQEVTTTRLPAGSQEPVKDVHVARGFSYRKSVHQIPAQRDLYRDFRKENVGNVVSLGSAVSTSNKITRLEQRKEPWTLGLHSSNKR-SILRSNYVKEKSVHAIQVPARSAGKTWREQQQWGLEDEKIAGVHWSYEETKTFLAILKESRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHMLEPCAFFEDMDALLNPAARAPSTDKPKEMIPVPRLKRIAISAKEHISLVEEEEAAEDSDDDEIGIEFIRKSEIHGAPVLFQNLSGVHWGYEETKTFLDILRETRFYEALQACHRK-SKLYGAVAEQLRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALINSRASAPSPSTPEEVPSPSRQERGGIEVEPQEPTGWEPEETSQEAVIEDSCSERMSEEEIVQEPEFQGPPGLLQSPNDFEIGSSIKEDPTQIVYKDMEQHRALIEKSKRVVSQSTDPSKYRKRECISGRQWENLQGIRQGKPMSQPRDLGKAVVHQRPFVGKRPYRLLKYGESFGRSTRLMCRMTHHKENPYKCGVCGKCFGRSRSLIRHQRIHTGEKPFKCLDCGKSFNDSSNFGAHQRIHTGEKPYRCGECGKCFSQSSSLIIHQRTHTGEKPYQCGECGKSFTNSSHFSAHRRVHTGENPYKCVDCEKSFNNCTRFREHRRIHTGEKPYGCAQCGKRFSKSSVLTKHREVHVREKPLPHPPSLYCPENPHKGKTDEFRKTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W2G2-1", "uniprot_id": "Q9W2G2_DROME", "id": "Q9W2G2-1", "name": "phosphoribosylaminoimidazolesuccinocarboxamide synthase", "aln": "----------------------------MSKFSLFNGNDEDEHETEQKYAHLMNLGNASHSVSENSSGKASRCKWTSAKVETFLEIIHQLKLQAALRRPRSNAKVFRMVSREMARRNCPKSPKHLRVKFHQMRRQYARARNGGE-------------PFEHFEAVHELMQGEDVSDLDEEALE-------------------------------------------------------------------SDSDMEADEDQSGMISETEGDDALDAS---------------------------------------------------------GSSVNIVARCKWAEGEVDLLLDLIHTLGLRAALLQK-RNAKVFKLLSKEMAKRNCHKGAEKLRIKFQQLRRLYNKVKNG-TGKTFEHFEAMRLVLDPTEEEAAAD-----------------AEAEAHLSSASDSDFNDSDEEEGDASQRSG-------------AHFWTDEEVDSFLLIIRDNGFFRALDGSRKRNFQTLVHISNILAKQDIKRTPHQLRNKLRLLCKRHREAK-EHGLDNVRILPRHFELFDELIQAPRENRESAISRLIRISKPSFLKPPGKPSVPLESDSDNSSSTCDLLRAAADSEDYVDAIEMEAEP------------------------TPIEALTAIIEGQKQLLAQIKTTN---------------------ESFLRQQREQQHQFLEQVSELMHR---------DREETLRRISEMLQPK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .::: ... *: :* : : :.: . . *. *:* ..::.: :*:. * :: * .: :.: . : .:. **. : ::*:* : . : *:.*: . :. *: ..:.. * :. .: : :.. . .. ..::.:. * . : :* :*: *.. :* ::: : :* **::*: ::: : : . : .*: * **:.*:: *.**:** :. .** * :*:* . .::: *: . * . .:. :...:* * *.. . .* **..:** *:::. *:.**:..::: : ::: * : .: ***.* *.*:: * * :*:.* * *:. : . *.: : . . :. * .: : * :*: :: :.: * ..*: : *::. . . * .::* *:.::* . .. . : * *: : .:.* . : :* . .: * :..* : * ", "identical_positions": 85, "similar_positions": 220, "identity": "8.75%" }, { "cls_id": "homologset.agr.MGI:2444061", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BW22-1", "uniprot_id": "CREST_MOUSE", "id": "Q8BW22-1", "name": "Calcium-responsive transactivator", "aln": "-------------------------------------------------------------------------------------------------------------------MSVAFASARPRGKG------------EVTQQTIQKMLDENHHLIQCILDYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLP---------------------------APPTQNMNLG----PGALSQSGSSQGLHPQGS---------------LSDTVSTGLPPASLMQG---------QIGNGPNHVSMQQTAQSTLPTTSMSLSGSGHGTGPGYSHSGPTSQS--------------------VPMQGQGAISNYVSRTNINMQSNP-----------------------------------------------------------VSMMHQQAATSHYN----------------------------------SAQGGSQHYQGQAPIAMMGQGGQGGSMMGQRP---------------------------MAPYRPSQQGSSQQYLG--QEEYYSEQYSHSQGSAEPMSQQYYPDGHGDY-----------------------------AYQQSSYTEQSYDRSFEDPTQHYYEGGN----------------------------------------------------------------------------------------------------------SQYSQQQAGYQQGTAQQQTYSQQQYPNQQSYPGQ------------------------------QQGYGPAQGAP-------------------SQYSSYQQGQGQQYGSYRTSQTGPSAQQQRPYGYEQ------------GQYGNYQQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91XJ0-1", "uniprot_id": "CREST_RAT", "id": "Q91XJ0-1", "name": "Calcium-responsive transcription coactivator", "aln": "-------------------------------------------------------------------------------------------------------------------MSVAFASARPRGKG------------EVTQQTIQKMLDENHHLIQCILDYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLP---------------------------APPTQNMNLG----PGALSQSGSSQGLHPQGS---------------LSDTVSTGLPPASLMQG---------QIGNGPNHVSMQQTAQSTLPTTSMSMSGSGHGTGPGYSHSGPTSQS--------------------VPMQGQGAISNYVSRTNINMQSNP-----------------------------------------------------------VSMMHQQAARPTTT----------------------------------QRRVEASITRARRPLHD-GPGWQGGSMMGQRP---------------------------MAPYRPSQQGSSQQYLG--QEEYYSEQYSHSQGSAEPMSQQYYPDGHSDY-----------------------------AYQQSSYTEQSYDRSFEDPTQHYYEGGN----------------------------------------------------------------------------------------------------------SQYSQQQAGYQQGTAQQQTYSQQQYPNQQSYPGQ------------------------------QQGYGPAQGAP-------------------SQYSGYQQGQGQQYGSYRTSQTGPSAQQQRPYGYEQ------------GQYGNYQQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75177-1", "uniprot_id": "CREST_HUMAN", "id": "O75177-1", "name": "Calcium-responsive transactivator", "aln": "-------------------------------------------------------------------------------------------------------------------MSVAFASARPRGKG------------EVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLP---------------------------APPTQNMNLG----PGALTQSGSSQGLHSQGS---------------LSDAISTGLPPSSLLQG---------QIGNGPSHVSMQQTAPNTLPTTSMSISG------PGYSHAGPASQG--------------------VPMQGQGTIGNYVSRTNINMQSNP-----------------------------------------------------------VSMMQQQAATSHYS----------------------------------SAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRP---------------------------MAPYRPSQQGSSQQYLG--QEEYYGEQYSHSQGAAEPMGQQYYPDGHGDY-----------------------------AYQQSSYTEQSYDRSFEESTQHYYEGGN----------------------------------------------------------------------------------------------------------SQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQ------------------------------QQGYGSAQGAP-------------------SQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQ------------GQYGNYQQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3G1-1", "uniprot_id": "Q9W3G1_DROME", "id": "Q9W3G1-1", "name": "SS18 N-terminal domain-containing protein", "aln": "MSAVYSPQPPQQQPQQQQQLQQQQQQPPPPQQQQQQQQQLQQPPPNSAPNQQPPGSGVGPGGGGGGIPGGGGILSMGMQQQQQRPPMGVPGSPGSIISGGGGGGGVIGGGGMPGGGMMVTPTSTPRGGANMQGGGGGGVPQQVNSAQIQKMLDENCGLIQTIQDFQSMGKAQECMSYHVALHRNLVYLAQLADPAMNISQILPPPHILQTQAMQQGGQQTPPTGPHGMLGGPPQQQQQPGQGPVPGQPGQGPPQMGMQQHGGDPQGPPVQMPPYGAQQQPQPHPGLPPGAQQQSQQQQQQQQQQQQQQQQQQQQQQAAAAAAAAAAAAAVAAGQQQGPQVSQAGPQQQQQQQHPVYRNAQGQGQPGAGQVPGQGQGPVQSVINPNAAPNQQRPNNGPLSGPQNPQQQQQQPQPGGQQPPNQQQQQQQTGPGGPGPQPGAGGPGVPPPQSPYRVSYQQQQQQHSHYPGYPPQPQTQYQPQGAYPYGPPTQGYGPPPPGPPNAAQGGYHHGPAGAATGASGHGYQPNAGAGQGPPPGAYPPPPGSQQVPPVPGQQQPPPGPPPPGQPPTGGQQQPPPGPPQSQYGPPPPQNSAGGPPPMGYAGYPPNPGQYGQAGAGGGPPPSGYWPPPPPTSSAQSPYQAYQQQQQQQAAAGGGAGAPPGSSYPGGPPTSGAAPPPPPGGAYSTTAPSQTPPPQGGGGAGGGNNNPNGPNAQQSTPPPQGGAGGGAGPSGPGGAGQQYAGPPQQQPQQQQPPGVVVSGVAPLPTQVQPTYSTPGNYNQQPGAPPPPNQQQQQQQQQQQQQQQTPPSAGGSAGGGGAPNAQGQGNQQPPPNGATPPMPPNQYQPAPGAPQGPYGGPPPPQAYGPPPPGSAYPGHAYHQPPQAGGYAQYPPTQGYQGYRPAGAQMPPPGAPQGPPPTGAYGYYSQQPPQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .:: *** . :*.. ******** *** * ::** **: ** .*: ********* :**. *:..:** .** *: : * ** *. .. *:: :*. . .****.: *. * : .: . **:* : .::: : . * *::** .* ** ****.: . :. . *..* ** :** . : . . * * * .: ** * .* :*. *..* * *.:* .:* *.. **. ** . .:* ****.. : : . . .. * ** .:*.** .. *** .*** .**: *. : * .* *** * *..: * * *.* . . * ** * : * ** *.* ", "identical_positions": 131, "similar_positions": 107, "identity": "14.15%" }, { "cls_id": "homologset.agr.MGI:2444067", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6N5-1", "uniprot_id": "G3V6N5_RAT", "id": "G3V6N5-1", "name": "Solute carrier family 66 member 3", "aln": "------------MEAG----LLWFCNWSTLGVCAALKLPQIYAQLAARSARGISLPSLLLELAGFLVFLRYQHYYGNPLLTYLEYPILIVQDIVLLLFVFHFNGNVKQALPYMAVFVSS----WFILSLQKWIIDLAMNLCTVISAASKFAQLQYLWKAQDSGAVSALTWGLSAYTCATRIITTLMTTNDLTILLRFVIMLALNIWVTATVLHYRKSVTKAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C6U2-1", "uniprot_id": "S66A3_MOUSE", "id": "Q8C6U2-1", "name": "Solute carrier family 66 member 3", "aln": "------------MEAG----LLWFCNWSTLGVCAALKLPQIYAQLAARSARGISLPSLLLELAGFLVFLRYQHYYGNPLLTYLEYPILIAQDIVLLLFVFHFNGNVKQALPYMAVFVSS----WFILSLQKWIIDLAMNLCTVISAASKFAQLQYLWKVQDSGAVSALTWGLSAYTCATRIITTLMTTNDLTILIRFVIMLALNIWVTATVLHYRKSATKAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N755-1", "uniprot_id": "S66A3_HUMAN", "id": "Q8N755-1", "name": "Solute carrier family 66 member 3", "aln": "------------MEAA----LLGLCNWSTLGVCAALKLPQISAVLAARSARGLSLPSLLLELAGFLVFLRYQCYYGYPPLTYLEYPILIAQDVILLLCIFHFNGNVKQATPYIAVLVSS----WFILALQKWIIDLAMNLCTFISAASKFAQLQCLWKTRDSGTVSALTWSLSSYTCATRIITTLMTTNDFTILLRFVIMLALNIWVTVTVLRYRKTAIKAE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZF3-1", "uniprot_id": "Q9VZF3_DROME", "id": "Q9VZF3-1", "name": "Solute carrier family 66 member 3", "aln": "MSGALGDVVSEYLERGPVLVVADLLSLITVSSCLVIKVPQINTIRANESSKGISVLGLCLELFSYTVMLSYNYTSGYDFLSYMEYPVLLLQEYALIYYAFKYQDLLGRRTQVVAILYSIVATLIYMKLFPIIILKFLVPFCTPIGATSKVLQLLAILRTKDASSVSRTTWALSAFTNMTRIYTVFFQSHDWMLLSNFLISTFLSASVFTAACVYKKKAKAE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . : : . *:. * .:*:*** : * .*::*:*: .* *** .: *:* *: * *:*:***:*: *: *: *:::. : : :*:: * :: : *:.: : :** *.*:**. ** : :.:*:.:** **.**::* *** *.:: ::* :* .*:* *. * .:. *:*.. ", "identical_positions": 59, "similar_positions": 72, "identity": "26.58%" }, { "cls_id": "homologset.agr.MGI:2444068", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TYU2-1", "uniprot_id": "AT135_MOUSE", "id": "Q3TYU2-1", "name": "Probable cation-transporting ATPase 13A5", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKSKKD----------------------------------GHQAVLNEGEENELEVFGYHTQNLRRALCLVTAILTLGAVQLMFYWRPEWWVWTSCIPCPLQEADTILLRT--TDEFRRYMRKKVFCLHLSTLKFPISKNPE-----------EPLVADHHSVINQAVMKPELKLRCIQVQKIRYVWDFLKKRFQKVGLLEDSNSCFDIHHTFGLGLTNEEQEVRRLVCGPNSIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHKLVEEHNKVQVTITVRDKGLQELESRLLVPGDILILPG--KISLPCDAILIDGSCVVNEGMLTGESIPVTKTPLPQTENTMPWKSHSLEDYR----KHVLFCGTEVIQVKPS-AQGLVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYNDAFKFMVFLACVGVVGFFYALGVYMYHEVPPRETATMALILLSATVPPVLPAALTIGNVYAQKRLKKEKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTAGNCFQAVHS------------------FASGEAVPWGPLCAAMTSCHSLILLDGTIQGDPLDLKMFEGTGWNMEDS--QVASCKFGMADSSTVIKPGPKAS---------------QSPVDSITILR---------------QFPFSSGLQRMSVIAQLAGDLHLHVYMKGAPEMVARFCRSETVPKNFSQELRNYTVQGFRVIALAHKTLKMER-LSDMDHLAREKVESELAFLGLLIMENRLKKETRPVLKELSEARIRTVMVTGDNLQTAITVAKNSEMIPVGSQVVIVEANEPGDLVPASVTWQLVGTQEPGSGK------------------------------------------------------KDTYIDIGNSSVPAGKG-------------------------------YHFAMSGKSYQVLFHHFY----SMLPQILVNGTIFARMSPGQKSSLVEEFQKLNYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSKTANIECVPHLIREGRAALVSSFGVFKYLTMYGIIQFIGTSLLYWQLQLFGNYQYLLQDVAITLMVSLTMSINHAYP-KLAPYRPAGQLLSPQLLLSVFMNSCFTCIVQVCTFLTVKQQPWYCEVYKYSECFLVNQSNLSANVSLDRNWTGNATLVPASVLSFEGTTLWPIVTFNCISAAFIFSKGKPFRKPIYANYLFSLLLASAAGLTIFILFCDFQDLYRKMEFIPTPTS-WRVSILIAAFVQFCVAFFVEDAVLQNRELWLFIKKEFG--FYSKSQYRILQRKLAEDSTWPPVNRTDYAVNGKNGFYVNRAYESPEEVPKGKLKLEEQASEQHFWTRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1MA70-1", "uniprot_id": "F1MA70_RAT", "id": "F1MA70-1", "name": "Cation-transporting ATPase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKSKTD----------------------------------GHQAVLNEGEENELEVFGYQTQNLRRALCLVTAILTLGAVQLMFYWRPEWWVWTSCIPCPLQEADIVLLRT--TDEFRRYMRKKVFCLHLSTLKIPISKNPG-----------EPLVADHHSVINQAVMKPELKLRCIQVQKIRYVWDFLKKRFQKVGLLEDSNSCFDIHHTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHKLVEDHNKVQVTITVRDKGLQELESRLLVPGDILILPG--KISLPCDAVLIDGSCVVNEGMLTGESIPVTKTPLPQTENTMPWKSHSLEDYR----KHVLFCGTEVIQVKPS-GQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYNDAFKFMVFLACIGVVGFFYALGVYLYHEVPPRETVTMALILLTATVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTAGNCFQAVHS------------------FASGEAVPWGPLCAAMASCHSLILLDGTIQGDPLDLKMFEGTGWNMEDG--QVASCKYSTADSGTVIKPGPNAS---------------QSPVDSITILR---------------QFPFSSGLQRMSVIAQLAGDLRLHVYMKGAPEMVARFCSSETVPKNFPQELRNYTVQGFRVIALAHKTLKMEK-VSDVERLAREKVESELAFLGLLIMENRLKNETRPVLQELSEARIRTVMVTGDNLQTAITVAKNSEMIPVGSQVIIVEANEPGDLVPASVTWQLVGTQEPGSEKKVSQGSQQCF---------------------------------RSPCRNHAFRFQDTYIDIGNSSVPCGKG-------------------------------YHFAMSGKSYQVLFHHFY----SMLPQILVNGTVFARMSPGQKSSLVEEFQKLNYYVGMCGDGANDCGALKMAHAGISLSEQEASVASPFTSKVANIECVPHLIREGRAALVSSFGVFKYLTMYGIIQFIGTSLLYWQLQLFGNYQYLLQDVAITLMVSLTMSINHAYP-KLAPYRPAGQLLSPQLLLSVFMNSCFTCIVLVCTFLSVKQQPWYCEVYKYSECFLVNQSNFSTNMGLERNWTGNATLVPASVLSFEGTTLWPIVTFNCISAAFIFSKGKPFRKPIYTNYLFSLLLTSAVGLTVFILFSDFQDIYRRMEFIPTTTS-WRISILVAAFVQFCVAFFVEDAILQNRELWLFIKKEFG--FYSKSQYRILQRKLAEDSTWPPTNRTDYAVNGKNGLYINRAYESPEQVPKGKLKLGGQASEQHFWTRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VNC0-1", "uniprot_id": "AT135_HUMAN", "id": "Q4VNC0-1", "name": "Probable cation-transporting ATPase 13A5", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEENSKK----------------------------------DHRALLNQGEEDELEVFGYRDHNVRKAFCLVASVLTCGGLLLVFYWRPQWRVWANCIPCPLQEADTVLLRT--TDEFQRYMRKKVFCLYLSTLKFPVSKKWE-----------ESLVADRHSVINQALIKPELKLRCMEVQKIRYVWNDLEKRFQKVGLLEDSNSCSDIHQTFGLGLTSEEQEVRRLVCGPNAIEVEIQPIWKLLVKQVLNPFYVFQAFTLTLWLSQGYIEYSVAIIILTVISIVLSVYDLRQQSVKLHNLVEDHNKVQVTIIVKDKGLEELESRLLVPGDILILPG--KFSLPCDAVLIDGSCVVNEGMLTGESIPVTKTPLPQMENTMPWKCHSLEDYR----KHVLFCGTEVIQVKPS-GQGPVRAVVLQTGYNTAKGDLVRSILYPRPLNFKLYSDAFKFIVFLACLGVMGFFYALGVYMYHGVPPKDTVTMALILLTVTVPPVLPAALTIGNVYAQKRLKKKKIFCISPQRINMCGQINLVCFDKTGTLTEDGLDLWGTVPTADNCFQEAHS------------------FASGQAVPWSPLCAAMASCHSLILLNGTIQGDPLDLKMFEGTAWKMEDC--IVDSCKFGTSVS-NIIKPGPKAS---------------KSPVEAIITLC---------------QFPFSSSLQRMSVIAQLAGENHFHVYMKGAPEMVARFCRSETVPKNFPQELRSYTVQGFRVIALAHKTLKMGN-LSEVEHLAREKVESELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIVEADEPEEFVPASVTWQLVENQETGPGK------------------------------------------------------KEIYMHTGNSSTPRGEGGS----------------------------CYHFAMSGKSYQVIFQHFN----SLLPKILVNGTVFARMSPGQKSSLIEEFQKLNYYVGMCGDGANDCGALKAAHAGISLSEQEASVASPFTSKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALLLYWQLQLFGNYQYLMQDVAITLMVCLTMSSTHAYP-KLAPYRPAGQLLSPPLLLSIFLNSCFSCIVQISAFLYVKQQPWYCEVYQYSECFLANQSNFSTNVSLERNWTGNATLIPGSILSFETTTLWPITTINYITVAFIFSKGKPFRKPIYTNYIFSFLLLAALGLTIFILFSDFQVIYRGMELIPTITS-WRVLILVVALTQFCVAFFVEDSILQNHELWLLIKREFG--FYSKSQYRTWQKKLAEDSTWPPINRTDYSGDGKNGFYINGGYESHEQIPKRKLKLGGQPTEQHFWARL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8DZ26-1", "uniprot_id": "A8DZ26_DROME", "id": "A8DZ26-1", "name": "Cation-transporting ATPase", "aln": "----------------------------------------------------------------------------------------------------MFASQSKACDSPSETVHL--------------QSLPNHIEDLKFRNSDVETDDDLHFPGIAAKNKILKLSWWHSPVDMHYVATESVQPKKSDKVPSNKIKKVENNNTLVNGCSKTSARSVPLLKYNRPDQDGDSEENITSVLEPNVDEIYSKDSERLVDDSK----------------------------------PCIGLLNPDQEDQMKVCGYRRSLMRTGFCWACIFLTGGLLRLVLHWWRHLYLYATCSQCSLEEAEQVLVTEDYQGKHKMYHVKQIQVLTSSNLKTLLEKEQQSIERTHIECDHVENVLQLSVHFTSAQFKKCSSIRIFRCKQLVYAWNNNTNRFQRINGLDLNIPCSYYHQQR--GLPVHEQISRRIVFGDNEITVPLRDFKTLLFLEVLNPFYVFQLFSVILWFTYDYYYYACVILLMSVFGITVSVLQTKKNQDVLQKTVYNTGNAWVVDHKG--LSKELPTRAIVPGDIIEIPSS-GCTLHCDAILISGNCILDESMLTGESVPVTKTPLPSKRD----MIFDKTEHA----RHTLFCGTKVIQTRYI-GSKKVLAFVINTGNITAKGELIRSILYPPPVDYKFEQDSYKFIQFLAIIACVGFIYTLVTKILRGTDPVKIAVESLDLITIVVPPALPAAMTVGRFYAQKRLKTSEIFCISPRSINVAGSINCCCFDKTGTLTEDGLDMWGVVPKSS-TNQFQIP------------------LKSVDRLPFDHFLFGMVTCHSITILNGRMMGDPLDLKMFESTGWELEDSNNIPDTEKYGILYPTILRQPRGGLSGMAETESGSKNEIKRQSSVDDLLATVGISPSQKNFDHGIVREFPFTSALQRMSVVTRCLSDQVFNVYCKGSPEMLKKLCKPQSLPDNYSQQLSEFAKKGYRIIAIAFKALSHKMNYTKVQRLSREEVENNMEFLGFVILENRLKPDTTKVINALNAAKIRTIMITGDNILTAISVARDCGIVSPSQSVITVHADPIGDSANIQTNTGTECNFDNSSDKHYKLHYTLDLGSKTSRAYLFKSCFNSNLFDPETPEFTAQVGKTIFHMESTNSLVNESTSSYAESGLPTSDSLASVKTIDTWTHNDAELGIKHTPDESWRRQECIFAMDGKTWQIVKDYFP----EEMEILLTRGSIYARMSPDQKQALVIELQNLDYCVAMCGDGANDCGALKVAHAGISLSETEASIASPFTSRNPTISAVLKVIKEGRAALVTSFGIFKYMAAYSLVQFISVMILYSIDSNLTDKQYLYVDLGLISIFAFFFGKTESFDGMLVEQVPLSSLISSTPLASLLLHLTVVTAFQVTCWVHLHQQPWFKAFEPADEDHLG---------------------------CFENYTMFCISSFQYIILAFVFSKGAPYRKPLWSNWPLCLAFIVNLCIIVYLVLYPSDWVASFFQLIVPPTMRFRYVMLAYGAASFICHIFVESFLVEYLVFKKYQVKREKNWVTSKQKYMRLEHDISNIKNWPPITEVYEPNNLIDCETEQPTYVSLHAEQNHDTQLGKFPGFC------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12697-1", "uniprot_id": "YPK9_YEAST", "id": "Q12697-1", "name": "Vacuolar cation-transporting ATPase YPK9", "aln": "MDIPSSNQIQHGQRSERNRRMPRASFSSTATTSTAATLTSAMVLDQNNSEPYAGATFEAVPSSIVSFHHPHSFQSSNLPSPHSSGNLEQRGRRLTESEPLVLSSAEQSRSSSRNPSHFRFFTQEQISNAEGASTLENTDYDMAWDATPAYEQDRIYGTGLSSRRSSIRSFSRASSLSNAKSYGSFSKRGRSGSRAPQRLGENSDTGFVYHSATHSSSSLSRYTTRERIPIELESQTDEILEDESSTHSLESSDSRRSASENNRGSFSGHDDVHNQHSEYLKPDYHEKFYPQYAPNLHYQRFYIAEEDLVIGIAAYQTSKFWYIIYNLCCFLTFGLVYLLTRWLPHLKVKLYGVKVPLAKAEWVVIEN-EFGEFVIQPIDRQWYNRPLSTVLPFENYPNP--------SYEPNDINLSHHHANEINPNVPILITFEYRYIKFIYSPLDDLFKTNNNWIDPDWVDLSTVSN--GLTKGVQEDRELAFGKNQINLRMKTTSEILFNEVLHPFYVFQVFSIILWGIDEYYYYAACIFLISVLSIFDSLNEQKKVSRNLAEMSHFHCDVRV---LRDKFWTTISSSELVPGDIYEVSDPNITILPCDSILLSSDCIVNESMLTGESVPVSKFPATEETMYQLCDDFQSTQISSFVSKSFLYNGTNIIRARIAPGQTAALAMVVRTGFSTTKGSLVRSMVFPKPTGFKFYRDSFKYIGFMSLIAIFGFCVSCVQFIKLGLDKKTMILRALDIITIVVPPALPATLTIGTNFALSRLKEKGIFCISPTRLNISGKIDVMCFDKTGTLTEDGLDVLGVQISEPNGVRGQKFGELLSDIRQVFPKFSLNDCSSPLDFKSRNFFMSLLTCHSLRSVDGNLLGDPLDFKMFQFTGWSFEEDFQKRAFHSLYEGRHEDDVFPENSEIIPAVVHPDSNNRENTFTDNDPHNFLG------------VVRSFEFLSELRRMSVIVKTNNDDVYWSFTKGAPEVISEICNKSTLPADFEEVLRCYTHNGYRVIACAGKTLPKRT-WLYSQKVSREEVESNLEFLGFIIFQNKLKKETSETLKSLQDANIRTIMCTGDNILTAISVGREAGLIQCSRVYVPSINDTPLHGEPVIVWRDVNEPDKILDTK------------------------------------------------------TLKPVKLGNNSVESLRECN-----------------------------YTLAVSGDVFRLLFRDENEIPEEYLNEILLNSSIYARMSPDEKHELMIQLQKLDYTVGFCGDGANDCGALKAADVGISLSEAEASVAAPFTSKIFNISCVLDVIREGRAALVTSFACFQYMSLYSAIQFITITILYSRGSNLGDFQFLYIDLLLIVPIAICMSWSKSYE-KIDKKRPSANLVSPKILVPLLISVFLVFLFQFIPWIIVQKMSWYIKPIVGGDDAVQ---------------------------SSDNTVLFFVSNFQYILTAIVLSVGPPYREPMSKNFEFIVDITVSIGASLLLMTLDTESYLGKMLQLTPISNSFTMFIIVWVILNYYAQLYIPPSIKG------WLKKKKS-----SKKYKLLIQEEMKLKEV------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .... . :: : : .*: . : .** * : *: * . : .* :*: ::: .:. .: . ..: : . : :. : : : :. . *: . **. * *.:. * * * : :: :*. :**:****** *:: ** * *: *::::*:.* *: : :: . * : .. * : : :***** :.. * **::*:...*:::*.******:**:* * .. .. : : *: **::*:.: .. . *.*:.** *:**.*:**:::* * .:*: *::*:: *:: :. .** : : :* ::: .***.***::*:* :* .*** . ****** :*:.*.*: **************: *. . : * . : .: :***: ::* : *****:***: *.*.:*: . * : : .* * * *:****:.: .: : **:**:: .:* .::* :: : * :: :*:*:** * *:* ::::**:**.:: ***::*::*:** :* .:: *. *.***:* ****: ***:*.::. :: . : : . . . * .:.. :*:.*. :::: . : :* ..:::*****.:* *: ::*:*:* *.:************ *..****** ***:*:****: .*..* .:*:*******:**. *:*:: *. :*** :** . : : *:* *: : ..: :. ..:: : * ..*:*. * .::: . . . :: ::: .*: .: : . : .:: : .:: * *:::* * *:*:*: *: : . : : :: : : : . : : :: .: ::: : :. ..:* :. : . ", "identical_positions": 260, "similar_positions": 358, "identity": "15.58%" }, { "cls_id": "homologset.agr.MGI:2444069", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AU98-1", "uniprot_id": "A0A8I6AU98_RAT", "id": "A0A8I6AU98-1", "name": "", "aln": "MALHIHEACILLLVIPGLVTPAAISHEDYPADEGDQASSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPIYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDDCNICHCHNGDWWKPAQCSKRECQGKQTV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q505H4-1", "uniprot_id": "VWC2L_MOUSE", "id": "Q505H4-1", "name": "von Willebrand factor C domain-containing protein 2-like", "aln": "MALHIHEACILLLVIPGLVTSAAISHEDYPADEGDQASSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPIYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDDCNICHCHNGDWWKPAQCSKRECQGKQTV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RUY7-1", "uniprot_id": "VWC2L_HUMAN", "id": "B2RUY7-1", "name": "von Willebrand factor C domain-containing protein 2-like", "aln": "MALHIHEACILLLVIPGLVTSAAISHEDYPADEGDQISSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKRECQGKQTV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UZC8-1", "uniprot_id": "VWC2L_DANRE", "id": "B0UZC8-1", "name": "von Willebrand factor C domain-containing protein 2-like", "aln": "MGPFLPAICVVLLALNAAVSPASVGPEDYPAADEAERTANNDIIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCTEDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYRGKTYKILEEFKPSPCEWCRCEPNNEVHCVVADCAVPECVNPVYEPEQCCPICKNGPNCFAGTTIIPAGIEVKVDDCTICRCHSGDWWKPAQCLRRECLNGQATS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. .: *::**.: . *:.*::. ***** : : ::*:::***********************************: **************************************:**.*******************.******************:********:***********************:*.**:**.********* :*** . *:. ", "identical_positions": 173, "similar_positions": 34, "identity": "77.58%" }, { "cls_id": "homologset.agr.MGI:2444070", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYP9-1", "uniprot_id": "D3ZYP9_RAT", "id": "D3ZYP9-1", "name": "", "aln": "--------------------------IRKPSCSEVTQPAWGHPSWLCLHSFWLQTQDSMRKQEVWTDRETCWAKNAGSPAEQVKTLVDLLAGKGSQ---LLLACNKMPDSPVGSQS-NESRLQKHCEALLSRVGNDPE---LGSPSHQLASLILVEGLTDLQLKEHDFTQVEAARGVW-RPGRAITLDRLFLPLSRVSIPPRVSVTIGVAGVGKTTLVRHFVRCWARGQVGKGFSWVLPLTFRDLNTYEKLSADKLIYSIFSNAGEAG-AVTAPDRALLVLDGLDECKTPLEFSNTVACTDPKKEIQVDHLITNIIRGNLFPEISVWITSRPSAAGQIPGGLVDRMTEIRGLTEEEIKVCLEQMFP----------------EDQNLLGQVLSQVQANRGLYLMCTIPAFCRLTGLALGHLYRTRLAVQDAELPLPQTLCELYSWYFRMALGGEGQDKGKVSPRIEQVMQGARKMVGTLGRLAFHGLVKKKYVFYEQDMKAFGVDLALLQSSLCSCLLQREETLAS-SVAYCFTHLSLQEFMAATYYYSASKRAIFDLFTESGMSWPRLGFLTHFRCAVQRATQAKD---GRLDVFLRFLSGLLSPRVNALLAGSL-LAQGEHQSYRNQVAEVLQGFLHPD--TAVCARAINILYCLSELRHTDLARSVEEAMRSGTLAGMTSPPHRTALAYLLQMSDICSWEADFSLCLSQRVLQSLLPQLLYCQSLRLDNNQFQDPVMELLGSVLSGKDCRIQKISLAENQIGNKGARGLARSLLVNRSLVTLDLRSNSIGPQGAKALADALKINRTLTSLSLQSNVIKDDGVMYMAEALVSNQIISTLQLQKNLIGPRGAQQMADALKKNRSLRELMFSSNTIGDRGAMALAEALKVNQGLENLDLQSNAISNTGVAVLMRALCTNQTLSSLNLRENSISPEGAQALAQALCRNTTLKHLDLTANLLHDQGAQAIATAVGENCSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLTALYLQVASIGSQGAQALGEALAVNRTLEILDLRGNDVGVAGAKALANGLKLNSSLRRLNLQENSLGMDGAIYVATALSENHGLHHINLQGNPIGESGARMISQAIEKNAPTCTVEM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DU56-1", "uniprot_id": "NLRC3_MOUSE", "id": "Q5DU56-1", "name": "Protein NLRC3", "aln": "--------------------------MRR--------------------RYSHDPPGSFRETKVFGFRG----------EYGCKALVDLLAGKGSQ---LLQVRDKMPDSPLGSQS-NESRIPKHSEALLSRVGNDPE---LGSPSHRLASLMLVEGLTDLQLKEHDFTQVEATRGVW-HPARVITLDRLFLPLSRVSIPPRVSLTIGVAGVGKTTLVRHFVHCWARGQVGKGFSRVLPLTFRDLNTYEKLSADRLIQSIFSSIGEASLVATAPDRVLLVLDGLDECKTPLEFSNTMACSDPKKEIQVDHLITNIIRGNLFPEISVWITSRPSAAGQIPGGLVDRMTEIRGLTEEEIKVCLEQMFP----------------EEQNLLGQVLSQVQANRALYLMCTVPAFCRLTGLALGHLYRTRLAVQDIELPLPQTLCELYSWYFRMALGGEGQDKEKVSPRIKQVTQGARKMVGTLGRLAFHGLVKKKYVFYEQDMKAFGVDLALLQNTLCSCLLQREETLAS-SVAYCFIHLSLQEFVAATYYYSASKRAIFDLFTESGMSWPRLGFLAHFRCAAQRATQAKD---GRLDVFLRFLSGLLSPRVNTLLAGSL-LSQGEHQSYRDQVAEVLQGFLHPD--AAVCARAINVLYCLSELRHTELACSVEEAMRSGTLAGMTSPSHRTALAYLLQMSDICSPEADFSLCLSQHVLQSLLPQLLYCQSLRLDNNQFQDPVMELLGSVLSGKDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDVGAAGAKALANALKLNSSLRRLNLQENSLGMDGAIFVASALSENHGLHHINLQGNPIGESAARMISEAIKTNAPTCTVEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTR2-1", "uniprot_id": "NLRC3_HUMAN", "id": "Q7RTR2-1", "name": "NLR family CARD domain-containing protein 3", "aln": "----------------------------------------------------------MRKQEVRTGREAGQGHGTGSPAEQVKALMDLLAGKGSQGSQAPQALDRTPDAPLGPCS-NDSRIQRHRKALLSKVGGGPE---LGGPWHRLASLLLVEGLTDLQLREHDFTQVEATRGGG-HPARTVALDRLFLPLSRVSVPPRVSITIGVAGMGKTTLVRHFVRLWAHGQVGKDFSLVLPLTFRDLNTHEKLCADRLICSVFPHVGEPSLAVAVPARALLILDGLDECRTPLDFSNTVACTDPKKEIPVDHLITNIIRGNLFPEVSIWITSRPSASGQIPGGLVDRMTEIRGFNEEEIKVCLEQMFP----------------EDQALLGWMLSQVQADRALYLMCTVPAFCRLTGMALGHLWRSRTGPQDAELWPPRTLCELYSWYFRMALSGEGQEKGKASPRIEQVAHGGRKMVGTLGRLAFHGLLKKKYVFYEQDMKAFGVDLALLQGAPCSCFLQREETLAS-SVAYCFTHLSLQEFVAAAYYYGASRRAIFDLFTESGVSWPRLGFLTHFRSAAQRAMQAED---GRLDVFLRFLSGLLSPRVNALLAGSL-LAQGEHQAYRTQVAELLQGCLRPD--AAVCARAINVLHCLHELQHTELARSVEEAMESGALARLTGPAHRAALAYLLQVSDACAQEANLSLSLSQGVLQSLLPQLLYCRKLRLDTNQFQDPVMELLGSVLSGKDCRIQKISLAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAICIATALSGNHRLQHINLQGNHIGDSGARMISEAIKTNAPTCTVEM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3APF3-1", "uniprot_id": "A0A8M3APF3_DANRE", "id": "A0A8M3APF3-1", "name": "", "aln": "MDRHSQIPWQEYCYLDLKSNAPKQETSKRMEDHGWLRRHQPLLHRFLSTSILVNVVHQMRKADLLSTQEAGLIQEMGSLKDKVHLLVEVLSVSDPHGAALQAYLQSSYQTEYNLITIHDSVVQPYKDTLLQWLKEDENSLAQVAGSSQGFTILLIESVSDLQQREHDLVQVSVNRGAGPLHGRALGLDKLIAPLTRVSTAPRVTLTVGVAGSGKSRMVSRFIRLWSSGQIYPELSLAIPIACWELSSYDRISVERLLRLFVPYDNMDVIIFNESCKVLLILDGLEEFRQTLDFADAPPTSDPRREIPVSDLIANIVRGNLLPGATLWLLSRPGIGAKVPAGLVDRVTEAPPLSQTQIKDYTNHCITNALDVYSLESSSSQTDIPQDLSSQVWTYLNSQKLLLILSSVPAICHVIVTTLSRLIK----IESEATPLPRTLTEVYAHYCWPHLSKS------------DTASGIRKSLNTLGRLAFYSLLRRRYTFVESELRTYGVDVPPQVGTLSYRILQRKQSWSSDNKAWQFTHTSVQEFLGALYYYVSSRRAVFDLFSESGVSWPRIGFHSHYRAALQKTNQSDATLQGSLDLFMRFLSGLLSPTAGVLLGGPLGVSREEQVTQRTTAMTLLQNAVAAAGGDAVSMRSVNMVTCLAELQQGEWLRSIEEDLISCGLRGKLKGGVCAVLAYLLLVSDSCTEETQLSNCLDSSSLKRLLPQLLYCSKLRMENNEFKEGAMELLGSLLSAKECHIQMLSLADNSISSKGVKPLSRALLVNRTLTTLDLRGNNIGAKGAKTLCEALKLNQFLVSVNLQNNHIEDEGARSLSEVLQSNRKLTTLNVQKNGIGPEGMKKIAEGLIKNQTLQDFNVSSNHLGDLGTVALAQALMVNHVLHTLSLQSNSVSDRGIKALSHALQSNRGLCCLNLRENSIGVAGAKDIAKALKVNTCLRELDLTANLLHDEGVTAIAEAMRVNRSISSLHLQWNFMKAGAAKALAESLSSNTCIQLLDLQENALGDNGVIALAAALMSNSSLTVLYLQGVSAGKSGAVALADAMVVNKTLHTLDLRGNSIGMEGAKAFSSALKNNRSLRSLNLQENSLGMDGAIFIATALRGNHQLTYINLQGNGIGESGAKVVSDAIKAGAPDCVVDI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: .: : : *:::*: ...: : :: . : ::* : : .:**. : . : . : :::*:*.::*** :***:.**.. ** .*.: **:*: **:*** .***::*:**** **: :* :*:: *: **: :* .:*:: :*.:::::..::*: ... . . :.**:****:* : .*:*::: . :**::** *..**:**:****:* ::*: ***. ..::*.*****:** :.: :** :: :. * * . : : ::::: * ::.::**:*:: :*.:* : :. *:** *:*: * *. . :. * ** :.*******:.*::::*.* *.:::::***:. .: . :***::: :* . *: * * *:***:.* *** :*:**:****:***:****:** :*:*.* *:: *:. * **:*:********* ...**.*.* ::: *: : * . :**. : . **. *::*:: ** **:: : *:** : * * :.***** :** *: *:::* .*.. *: ******** .**::.*:*:: .******:**.*:*:*: :***:*.*..**.: *:*:*****:* :****.*.**. ***:*.:***:*: *.*:.**.* :.*:*. ::*.* **: :: *::*** ** * :::*:.* :*::*: : .*** :** *: ***:** **: *..*.****::*: *: .* ** :*: * .*.******. **: :::** *. *:.**********.*. *** *: * ::: *******::****:**.::*. * : *******:**:*. ::* ** *::* .**** .* * .** .*.:*:.**:**. ****** :* ****::..** * *** ************** :*:** ** * :****** **:*.*:::*:**: .** *.*::", "identical_positions": 425, "similar_positions": 362, "identity": "36.92%" }, { "cls_id": "homologset.agr.MGI:2444084", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUA2-1", "uniprot_id": "D3ZUA2_RAT", "id": "D3ZUA2-1", "name": "NACHT, LRR and PYD domains-containing protein 10", "aln": "-----------MALARANSPQEALLWALNDLEENS----------FKTLKFHLRDVT----QFHLARGELEGLSQVDLASKLISMYGAQEAVRVVGRSLQ-AMNLMELVDYLNQVCLNDYREIYREHVLCLEERQDWGVNSSHNKLLLVAT---SSSGSLRSPSCSDLEQELDPVHVETLFAPEAESYSTPPIVVMQGSAGTGKTTLVKKLVQDWAKGKLYPGQFDYVFYVSCREVVLLP-KCDLPNLICWCCGDDQAPVTEILRQP-ERLLFILDGYDELQK----------------SSRAERVLHILMRRREVP-CSLLITTRPPALQSLEPMLGE-RRHVHVLGFSEEERETYFCSYFMDKEQLRNALEFVQNNAVLYKACQVPGICWVVCSWLKGKMARGQEVSETPSNSTDIFTAYVSTFLPTDGNGDSSELTRHKVLRGLCSLAAEGMRHQRLLFEEDVLRKHSLDGPSLTAFLNCTDYREGLGIKKLYSFCHISFQEFFYAMSFLVKEDQGQLGEATHKEVAKLVDQ---ENYEEVTLS-----------LQFLFDMLKTDNTLSLGLKFCFKIAPSVRQDLKHFKEQVVA------------------------------IKYNRSWDLEFS------LYDSKIKKLKQGIQMKDVIFNVQHSDEKKSGKKKP------------FSVTSRFGKG----PILETGKSTRKQKKASNGKSRETEEPPAQDGGKSRLASRGKGNKEINDK-DGGVYGQEDGEGQEVKKGGEILDEMNG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CCN1-1", "uniprot_id": "NAL10_MOUSE", "id": "Q8CCN1-1", "name": "NACHT, LRR and PYD domains-containing protein 10", "aln": "-----------MALARANSPQEALLWALNDLEENS----------FKTLKFHLRDVT----QFHLARGELESLSQVDLASKLISMYGAQEAVRVVSRSLL-AMNLMELVDYLNQVCLNDYREIYREHVRCLEERQDWGVNSSHNKLLLMAT---SSSGGRRSPSCSDLEQELDPVDVETLFAPEAESYSTPPIVVMQGSAGTGKTTLVKKLVQDWSKGKLYPGQFDYVFYVSCREVVLLP-KCDLPNLICWCCGDDQAPVTEILRQP-GRLLFILDGYDELQK----------------SSRAECVLHILMRRREVP-CSLLITTRPPALQSLEPMLGE-RRHVLVLGFSEEERETYFSSCFTDKEQLKNALEFVQNNAVLYKACQVPGICWVVCSWLKKKMARGQEVSETPSNSTDIFTAYVSTFLPTDGNGDSSELTRHKVLKSLCSLAAEGMRHQRLLFEEEVLRKHGLDGPSLTAFLNCIDYRAGLGIKKFYSFRHISFQEFFYAMSFLVKEDQSQQGEATHKEVAKLVDP---ENHEEVTLS-----------LQFLFDMLKTEGTLSLGLKFCFRIAPSVRQDLKHFKEQIEA------------------------------IKYKRSWDLEFS------LYDSKIKKLTQGIQMKDVILNVQHLDEKKSDKKKS------------VSVTSSFSSGKVQSPFLGNDKSTRKQKKASNGKSRGAEEP-APGVRNRRLASREKGHMEMNDKEDGGVEEQEDEEGQTLKKDGEMIDKMNG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86W26-1", "uniprot_id": "NAL10_HUMAN", "id": "Q86W26-1", "name": "NACHT, LRR and PYD domains-containing protein 10", "aln": "-----------MAMAKARKPREALLWALSDLEEND----------FKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLK-VMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGRYNQVLLVAK---PSSESPESLACPFPEQELESVTVEALFDSGEKPSLAPSLVVLQGSAGTGKTTLARKMVLDWATGTLYPGRFDYVFYVSCKEVVLLL-ESKLEQLLFWCCGDNQAPVTEILRQP-ERLLFILDGFDELQRPFEEK------LKKRGLSPKESLLHLLIRRHTLPTCSLLITTRPLALRNLEPLLKQ-ARHVHILGFSEEERARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRVLRSLCSLAAEGIQHQRFLFEEAELRKHNLDGPRLAAFLSSNDYQLGLAIKKFYSFRHISFQDFFHAMSYLVKEDQSRLGKESRREVQRLLEVKEQEGNDEMTLT-----------MQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMES------------------------------MKHNRTWDLEFS------LYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQSQNL------------FSVKSSLSHG------------PKEEQKCPS--VHGQKEGKDNIAGTQKEASTGKGR------------GTEETPKNTYI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HUA8-1", "uniprot_id": "A0AC58HUA8_DANRE", "id": "A0AC58HUA8-1", "name": "", "aln": "MDQDSERAQFVDAHWKTLVQRVIMVMAIADELQSDGMLEWEPYCKIKAAVTNQQKMRELYEVLQSGGDQVKSAFYSSLEKHEPYLLGDLGSIKLMGESLADCLNKYKMWIQKEYEYVTEYNSLPGENVLLSERFTQPLIIMRHRERREREEEMCSVGESFQQLLVSRNNADKDSSILDALFGADSKG-ISPNSVILQGNSGNGKSFTAQKIMLDWASGKLCKVEFDCLFHLKCKEVNHVSGEQSLTELLSYNSNLTSEQISRILQKSSEKVLILIDGFDELRFSFSDFSDHLKLKDLSEKAPREASLKVLLMGHILSKTSLLVTTRSTATNTLDSLLKHPKRFTEIMGFSEREVKEYFQKFFQDEELFIKAYEYVRSNETLITACSIPVICWIICTVLRERFSEGSDLTSGLETTTSIYVDFVCTLLEHHSQGLSQPVP--TLLRSLGQLAERGMLDTQVLFEEKSVDEMVSASPFLCKFL----FKRRIRKETMFSFMHLSFQEFFTALYYISQEEREFLDKLTERFHSQTQSYLSLYLDKDFPLKYGCPEPHFLPVVQFLCGLSNSEVSRSLQEMYNLSVPSFVQPQLREWILDMSKSGVYSYLPFILHCLYELHEKEFVQKAMEAWLELDMSWDPLSRTDCWALLYCLDCCPHFRSLKLNFAASELKMLQDVLCRTPKLGLTVQNVSDTDVTVLLSALGEGKQLGELKLNSSCLSDQSVQQVLKALHKQKKVGGLQISVKSITADTALILTDFLQSCSKAEWEEISGSLSTSDVESLCSSLRLFSFEGKLVVNVVRLCLSIQNQPSLSEIILNCPRSEASNIDIKSFTESFHNINCIAEESVDFDRNLHALLTLLTSMSGLSALNLSVPFLTETWASRVLFLVESSPKLTVINFHAGSWCSDGVKWLPGLLLEEGIKLLKESAKRPECIVNIRGFRCSKSSERCSRHTEHIDQLSCNQRVTIQFCGDQCTEDIKLKLVLPDEN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: : :: *: * :.. :* :.: . .:::. .* . * ::::: ..* :* :: . : :*..: *:* *. : : :.: . . . .. . : : :. :::** . : :* *::**.:*.**: .:*:: **:.*.* .** :*::.*:** : : .* :*: : .. . ::.**::. ::*:::**:***: : * *::*: : :. ***:***. * ..*:.:* . *.. ::****.* ** . * *:: .* : *:.* * .**.:* ***::*: *: :: .*. : . .:*.*: :*.*:* ..:* .. :. :*:.* .** .*: . :.**** : : .* * ** :: : :.::** *:***:** *: :: :*:: .: :.: : . .:..*. :*** .: :.: .* : : :.. : :*:.: :: :: . :** ** . :.:::: . ::: :: . . : : * :. * .:. :: . : : .. *: . ", "identical_positions": 119, "similar_positions": 248, "identity": "12.07%" }, { "cls_id": "homologset.agr.MGI:2444085", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q0VGK3-1", "uniprot_id": "GLCTK_RAT", "id": "Q0VGK3-1", "name": "Glycerate kinase", "aln": "MAAALQVLPCLLRAPSRPFLWGPPVARMTSGMALAEQARQLFDSAVGAVQPGPMLQRTLSLDPS---GK-----QLKVRDRTFQLQ-ENLYLVGFGKAVLGMAAAADELLGQHLVQGVISVPKGIRAAVELAGKQEMLLKPHSHIQVFEGAEDNLPDRDALRAAQAIQQLAERLTADDLLLVLISGGGSALLPAPIPPVTLEEKQTLTKLLAARGATIQELNTIRKALSQLKGGGLAQAAYPA-QVVSLILSDVIGDPLEVIASGPTVASTHSVQDCLHILNHYGLRAALPRSVKTVLSRADSDP------HGPHTCGHVLNVIIGSNSLALAEAQRQAEVLGYHAMVLSTAMQGDVRRVAQFYGLLARVAAACLTSSTAERPLEEEAKLHQLAAELQLPDLQLEEALEAVAKAK----GPVCLLAGGEPTVQLQGSGKGGRNQELALRVGAELGKQPLGPVDVLFLSGGTDGQDGPTKVAGAWVMSDLVSQASAEN--LDFATFLDNNDSYTFFCSFQGGTHLLHTGLTGTNVMDVHLLVFHPQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZY2-1", "uniprot_id": "GLCTK_MOUSE", "id": "Q8QZY2-1", "name": "Glycerate kinase", "aln": "MAAALQVLPCLLRAPSRPLLWGPPVARMTSGMALAEQARQLFDSAVGAVQPGPMLQRTLSLDPS---GR-----QLKVRDRTFQLR-ENLYLVGFGKAVLGMAAAAEELLAQHLVQGVISVPKGIRAAMEHAGKKEMLLKPHSRVQVFEGAEDNLPDRDALRAALTIQQLAEGLTADDLLLVLISGGGSALLPAPIPPVTLEEKQMLTKLLAARGATIQELNTIRKALSQLKGGGLAQAAYPA-QVISLILSDVIGDPLEVIASGPTVASAHSVQDCLHILNHYGLRAALPRSVKTVLSRADSDP------HGPHTCGHVLNVIIGSNSLALAEAQRQAEVLGYHAMVLSTAMQGDVKRVARFYGLLARVAAAHLTPSLAERPLEEEAELHQLAAELQLPDLQLEEALEAVAKAK----GPVCLLAGGEPTVQLQGSGKGGRNQELALHVGVELGRQPLGPIDVLFLSGGTDGQDGPTKVAGAWVMSDLISQASAES--LDIATSLTNNDSYTFFCRFRGGTHLLHTGLTGTNVMDVHLLILHPQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVS8-1", "uniprot_id": "GLCTK_HUMAN", "id": "Q8IVS8-1", "name": "Glycerate kinase", "aln": "MAAALQVLPRLARAPLHPLLWRGSVARLASSMALAEQARQLFESAVGAVLPGPMLHRALSLDPG---GR-----QLKVRDRNFQLR-QNLYLVGFGKAVLGMAAAAEELLGQHLVQGVISVPKGIRAAMERAGKQEMLLKPHSRVQVFEGAEDNLPDRDALRAALAIQQLAEGLTADDLLLVLISGGGSALLPAPIPPVTLEEKQTLTRLLAARGATIQELNTIRKALSQLKGGGLAQAAYPA-QVVSLILSDVVGDPVEVIASGPTVASSHNVQDCLHILNRYGLRAALPRSVKTVLSRADSDP------HGPHTCGHVLNVIIGSNVLALAEAQRQAEALGYQAVVLSAAMQGDVKSMAQFYGLLAHVARTRLTPSMAGASVEEDAQLHELAAELQIPDLQLEEALETMAWGR----GPVCLLAGGEPTVQLQGSGRGGRNQELALRVGAELRRWPLGPIDVLFLSGGTDGQDGPTEAAGAWVTPELASQAAAEG--LDIATFLAHNDSHTFFCCLQGGAHLLHTGMTGTNVMDTHLLFLRPR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08BL7-1", "uniprot_id": "GLCTK_DANRE", "id": "Q08BL7-1", "name": "Glycerate kinase", "aln": "---------------------------MSS---LNTRARAVFSAAVEGVHPDMVVRR--GLERH---GD-----KLHVGGQSFTLT-NNLYLVGFGKAVLGMAAEAERIVGDHLIKGVVSVPHGIQNTLRSHGKEKMLLESNSRITVMEGAKHNLPDTDAQKSAECIRDLASSLTEKDLLLVLISGGGSALLPAPAPPMSLQEKQDVTRKLAAAGATIQELNTVRRALSLLKGGGLAQCASPA-KVVALILSDVIGDPLDLIASGPTVRSDSSPEEVWAILDNYKLSDSLPSSVKEVLSKSISGQGSGVKNQPQEVKDNVLNVVIGSNTIALECASRKASELGLRPVILSPGVCGDVRSVARLYGLLSSFACS----PGKEPPPELAAEILKLGPEVGIESWDLCRTMNVLVGERKEGWGATCLLAGGEPTVKLSGKGRGGRNQELAMRVGLELSQGEVK-SGAVFLSGGTDGQDGPTEAAGAVADGELKEEAASQG--LDTDSFLANNDSFTFFSKLSEGRRLLNPGLTGTNVMDVHVMLLPPSPQKDLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQC4-1", "uniprot_id": "GLCTK_DROME", "id": "Q9VQC4-1", "name": "Glycerate kinase", "aln": "----------------------------MAKRQTWEQMRQIFVQAVNAVHPEKVFADFQKFDLRPQIGENATDISIKLNGERQDISGKTCHIVGFGKAVLGMANKVQQDLGATSAGGVLSVPVNTLKQFQQP--------VAPGLVVHEGAANNLPDENALKAAREIKQLAEKMTAQDILFVFISGGGSALLPLPRSPLTLEDKRSIADKLMKRGASIQEINAVRIACSDIKGGRLARLAGQAGLLVTFVLSDIIGDPLELIACGPTIQPEAAAS-PSDILKKHHVWEELSPEIRRVFEQPEEQK--------NTSLPEHKVFVVGSNVIATSTAAHEAERLGYIPCVLSCAVQGDVAQVAGDYQRLLHGIQE------AKQHGILDPQLREKYAFGERSYPTFRRALEDHMSSK----KPLFLICGGEPVIKVSGHGLGGRSQHLALLMSQALHR-DEAMRDCTFLSAGTDGIDGPTDAAGAFGDSSVVESYLGDHTLDELAETLRNCDSYNFYKNLAQGEHHVLTGHTGTNVMDLHFLVVP--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :* ** .* * :. :: * .::: .. : :. ::*********** .:. :. **:*** . .. . : * *** .**** :* ::* *::**. :* .*:*:*:********** * .*::*::*: :: * **:***:*::* * * :*** **: * * :::::***::***:::**.***: . . **..: : *. .:: *:.:. . . .::*** :* * ::*. ** . :** .: *** :* * * .:: : . : .::: : . *:.****.:::.* * ***.*.**: :. * : . ***.**** ****..*** .: .. .: : * : **..*: : * : : .* ******* *.:.. ", "identical_positions": 144, "similar_positions": 144, "identity": "26.13%" }, { "cls_id": "homologset.agr.MGI:2444086", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYT9-1", "uniprot_id": "ACSM5_RAT", "id": "Q6AYT9-1", "name": "Acyl-coenzyme A synthetase ACSM5, mitochondrial", "aln": "MRLWLRGLVYQARRSSWGVFRIHTQPPPPPIP-EVVATWEAISLGKRPVPEYFNFAHDVLDVWSQLEKTGHRPPNPAFWWVNGSGTEVKWTFEELGKQSRKAANILEGACGLKPGDRLMLVLPRLPEWWLTIVACMRTGVVMIPGISQLTQKDLKYRLQAARVKSIITSDALAPHVDAISADCPSLQSRLLVSDTSRPGWINFRELLRVASPEHNCLRTRSGDSMAIYFTSGTTGTPKMVEHSQCSYGLGFVASGRRLMALTESDIFWNTTDTGWVKAAWTLFSAWANGACVFVHELPQVDAQTILNTLCRFPITTICCVPTLFRLLVQEDLTRYKFQCLRHCLAGGEALNSDVRDKWKNQTGLEIHEGYGQSETVLICGNFRGSTIKSGSMGKASPPYDVQIVDEEGNVLPPGKEGNIAIRIKPTRPFCLFNCYLDNPEKTAASEQGDFYITGDRAHMDEDGYFWFVGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLSPAYVSHDPEALTRELQEHVKTVTAPYKYPRKVAFISELPKTVSGKILRSKLRNQEWGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGA8-1", "uniprot_id": "ACSM5_MOUSE", "id": "Q8BGA8-1", "name": "Acyl-coenzyme A synthetase ACSM5, mitochondrial", "aln": "MRLWLRGLACQALRSSWGVCRIHTQPPPPPIP-EVVATWEAISLGRQPVPEYFNFAHDVLDVWSQLEKTGHRPPNPAFWWVNGSGTEVKWTFEELGKQSRKAANVLEGVCGLQPGDRMMLVLPRLPDWWLISVACMRTGVVMIPGVSQLTAKDLKYRLQAARAKSIVTSDALAPQVDAISADCPSLQTKLLVSDTSRPGWINFRELLRAASPEHNCVRTRSGDSVAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWMALTESDIFWNTTDTGWVKAAWTLFSAWSNGACIFVHELPRVDAKTILNTLCRFPITTLCCVPTLFRLLVQEDLTRYKFQCLRHCLTGGEALNPDVRDKWKSQTGLELHEGYGQSETVVICGNSRNSTIKSGSMGKASPPYDVQIVDEEGNVLPPGKEGNIAVRIKPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRAHMDEDGYFWFLGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLSPAYASHDPEALTRELQEHVKTVTAPYKYPRKVAFISELPKTVSGKILRSKLRNQEWGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NUN0-1", "uniprot_id": "ACSM5_HUMAN", "id": "Q6NUN0-1", "name": "Acyl-coenzyme A synthetase ACSM5, mitochondrial", "aln": "MRPWLRHLVLQALRNSRAFCGSHGKPAPLPVPQKIVATWEAISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEWGK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *** *. ** *.* .. * :*.* *:* ::**********:: ****************:**::**************:*:*:**:*************:* *.***:****:********:*** *******.*****::*** *********:*.***:***:***:******:*****::*****:*****:******* **.****:**:* *.:**********:********.************ :***************************.**:*:******:***:.*****.:*****:*****:************:**.*****:******.***:*** ***:*::*********:**.* :. .*******************:********:***:*:**:******:**************************:**:******:****************************************************:*** **************** *************:*********** *****.****:", "identical_positions": 474, "similar_positions": 80, "identity": "81.87%" }, { "cls_id": "homologset.agr.MGI:2444087", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZT83-1", "uniprot_id": "D3ZT83_RAT", "id": "D3ZT83-1", "name": "Amino acid transporter", "aln": "MEWCQQAGLSMVLGAFLARGRAVCRHNGLLILSVLSVIVGCLLGFFLR--TQRLSPQEISYFQFPGELLMRMLKMLILPLVVSSLMSGLASLDAKTSSRLGILTVAYYLWTTFLAVVVGIIMVSIIHPGGAAQKETTEQSGKPVMS---SADALLDLVRNMFPANLVEATFKQYRTKTTPVIKSPKGAAEEAPPRGIVIYGVQEDNGSRVQNFALDLTPPPE-IVYKSEPGTSDGMNVLGIVIFSATMGIMLGRMGDSGTPLVSFCQCLNESVMKIVAVAGWYFPFGIVFLIAGKILEMDDPKAVGKKLGFYAVTVVCGLVVHGLLILPLLYFLITRKNPIVFIRGVLQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDINLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKDFA--QDMGTEKLLPCETKPVTLQEIVAAQQNGCVKSVAEASELTLGPKCPHHIPVQVEQDEELATASLDHCTIEINELETNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZR4-1", "uniprot_id": "EAA5_MOUSE", "id": "Q8JZR4-1", "name": "Excitatory amino acid transporter 5", "aln": "----------MVLDAVLARGRTVCKHNGLLILSVLSVIVGCLLGFFLR--TQRLSPQEISYFQFPGELLMRMLKMLILPLVVSSLMSGLASLDAKTSSRLGILTVAYYLWTTFLAVVVGIIMVSIIHPGGAAQKETTEQSGKPVMS---SADALLDLVRNMFPANLVEATFKQYRTKTTPVIKSPRGAAEEAPRR-IVIYGVQEDNGSRVQNFALDLTPPPE-IVYKSEPGTSDGMNVLGIVIFSATMGIMLGRMGDSGTPLVSFCQCLNESVMKIVAVAGWYFPFGIVFLIAGKILEMDDPKAVGKKLGFYAVTVVCGLVVHGLLILPLLYFLITKKNPIVFIRGVLQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDINLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKDFA--QDMGTEKLLPCETKPVTLQEIVAAQQNGCVKSVAEASELTLGPTCPHHIPVQVEQDEDPAAASLDHCTIEISELETNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00341-1", "uniprot_id": "EAA5_HUMAN", "id": "O00341-1", "name": "Excitatory amino acid transporter 5", "aln": "----------MVPHAILARGRDVCRRNGLLILSVLSVIVGCLLGFFLR--TRRLSPQEISYFQFPGELLMRMLKMMILPLVVSSLMSGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAAQKETTEQSGKPIMS---SADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPRRILIYGVQEENGSHVQNFALDLTPPPE-VVYKSEPGTSDGMNVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTVVCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKDFA--RDTGTEKLLPCETKPVSLQEIVAAQQNGCVKSVAEASELTLGPTCPHHVPVQVEQDEELPAASLNHCTIQISELETNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A6H2EJK0-1", "uniprot_id": "A0A6H2EJK0_DROME", "id": "A0A6H2EJK0-1", "name": "Amino acid transporter", "aln": "---------MTRPKQDGGKFKAFMQENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASKVLTPDTLMDLVRNMFTDNIIQSTMFQHRTEIY-------------------------------ENTSISPAQPMENWEFKS--AQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKC-LDNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLSKNDLASVDRLNAEPHELLELGPNGHEMKEXRQSSLGAYNRKRXVDMSRLWACFHILPSNDSDSDDYDDDDEEF------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : . :.* * : :*:.*:** *:**::: * . * :** *:.****:::**** :*:**:***: *.:..** . **::. :::**: **: **::** :*: ::** .*: *: .. * :.*:*:**:****. *::::*: *:**: :* ::. : * * :** . :* ****:*:**. :* :*** :.* * .* *.*::*.*.: . * *:*:.****.**:**:. *. :.**:* :**: **.:**: :.:::*: *:: * :* : *.* *:.*.*****:*:*:** *:* ** *::***:*******************:**** .: . .** *:::***********************:** :*** ..*:.******* ****** ***: ***.: :: *:.::*:* .:* * * : *.. . . . ::: * * :* : .:.:: . :. ", "identical_positions": 214, "similar_positions": 168, "identity": "37.02%" }, { "cls_id": "homologset.agr.MGI:2444096", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80TL0-1", "uniprot_id": "PPM1E_MOUSE", "id": "Q80TL0-1", "name": "Protein phosphatase 1E", "aln": "MAGCIPEEKTYRRFLELFLGEFRGPCGGGEPEPEPESEPEPEPE------AELVAAEAAEASGEEPGEDAATVEATEEGEQDQDPEPEDEAVEEETATEGEEEEEEE---AAAPGHSAVPPPPQPQLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHCIPKETDGTEGTVEIETVKLARSVFSKLHEICCSWVKDFPLRRRPQIYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASVHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAAR----ESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFG-AWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTED-YLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSS-----DNITVIVVFLRDMNKAVNVSEESEWTENSFQGGQEDGGDDKETHGECKRPWPQHQCSAPADLGYEGRVDSFTDRTSLSPGPQINVLEDPDYLDLTQIEASKPHSTQFLPPVEMIGPGAPKKD--LNELIMEERSVKSSLPERSGAGEPRVSFNLGSTGQQICRMENLSPVSSGLENEQFKSRGKTASRLYHLRHHYSKRQRGFRFNPKFYSFLSAREPSHKIGISLSSLTRSGKRNKMLRSSLPWRENSWEGYSGNV-KIRKRNDIPCPDFPWSYKI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80Z30-1", "uniprot_id": "PPM1E_RAT", "id": "Q80Z30-1", "name": "Protein phosphatase 1E", "aln": "MAGCIPEEKTYRRFLELFLGEFRGPCGGGEPEPEPESEPEPEPE------AELVAAEAAEASGEDPGEDAATVEAAEEGVQDQDPEPEEEAVEEEAAAEGEEEEEEEE--AAAPGHSAVPPP-QPQLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHCIPKETDGTEGTVEIETVKLARSVFSKLHEICCNWVKDFPLRRRPQIYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASVHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAAR----ESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFG-AWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTED-YLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSS-----DNITVIVVFLRDMNKAVNVSEESDWTENSFQGGQEDGGDDKENHGECKRPWPQHQCSAPADLGYEGRVDSFTDRTSLSPGPQINVLEDPDYLDLTQIETSKPHSTQFLPPVEMIGPGAPKKAY-VNELIMEESSVTPSQPERSGAGELLVSFNLGSTGQQICRMENLSPVYSGLENEQFKSPGKRASRLYHLRHHYSKRQRGFRFNPKFYSFFSAQESSRKIGISLSSLTRSGKRNKMLRSSLPWRENSWEGYSGNM-AIRKRNNISCPDLPWDYKI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WY54-2", "uniprot_id": "PPM1E_HUMAN", "id": "Q8WY54-2", "name": "Protein phosphatase 1E", "aln": "MAGCIPEEKTYRRFLELFLGEFRGPCGGGEPEPEPEPEPEPEPESEPEPEPELVEAEAAEASVEEPGEEAATVAATEEGDQEQDPEPE-----EEAAVEGEEEEEGAATAAAAPGHSAVPPP-PPQLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHYIPKETDGTEGTVEIETVKLARSVFSKLHEICCSWVKDFPLRRRPQLYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASIHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAAR----ESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFG-AWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTED-YLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSS-----DNITVIVVFLRDMNKAVNVSEESDWTENSFQGGQEDGGDDKENHGECKRPWPQHQCSAPADLGYDGRVDSFTDRTSLSPGSQINVLEDPGYLDLTQIEASKPHSAQFLLPVEMFGPGAPKKANLINELMMEKKSVQSSLPEWSGAGEFPTAFNLGSTGEQIYRMQSLSPVCSGLENEQFKSPGNRVSRLSHLRHHYSKKWHRFRFNPKFYSFLSAQEPSHKIGTSLSSLTGSGKRN-RIRSSLPWRQNSWKGYSENMRKLRKTHDIPCPDLPWSYKIE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ61-1", "uniprot_id": "Q9VJ61_DROME", "id": "Q9VJ61-1", "name": "PPM-type phosphatase domain-containing protein", "aln": "MSSDAIPASECAHLMEFKR-------------------------------FLVSTAEKAAAVSEEVVSRSCVTRTAN----------------ETYKVSGEER------------HAELVSAIWKQLETRG-CPAQFRIKLLHRSTQQLEQDLCFAKECEVTVE---GPPQYDLLKLQKFVASEFEKYILKLTDNSE------VDRLKDFADEAAPENCECHQQKEPLHTS---------AAVKNKPRKMEDRCVCLDRFGEMYELLDKT-TRFFGVFDGHSGSLSATYATSQLPQLLADQLKANPDPAAFSPDFYRNAFESAFLLADERFTQKKITSGTTSVCALITKDQLYIAWVGDSKALLVGKRTQLQLVKPHKPENPDERKRIETAGGTVLHAQGQWRVNGILNVARSIGDYSLEAVIA-EPDFVDVQLNEAHD-FLVLGTDGLWDHVPESLIIETVYDSLADTTMKLDDIPKLLIEAAKERDSQ-----DNITAVVVLLKPRHQIEHL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38089-1", "uniprot_id": "PP2C4_YEAST", "id": "P38089-1", "name": "Protein phosphatase 2C homolog 4", "aln": "---------------------------------------------------------MGQLLSHPLTEKTIEYNEYK--------------------------------------NNQASTGIVPRFYNCVGSMQGYRLTQEDAHLIRNENSVVYVRFFNPFIDKYETLSLNVFAVFDGHGGDDCSKFLSGGRHHRDGNGSSNGNGEPNAGLIKWIAYSFENHHYTSTTNN---------DSSKFKRSFNTLEGLVSQIFKDAFILQDEELYRHFANSS--CGSTAVVACIINEESLYVANCGDSRCILSSKSNGIKTMSFDHKPQHIG----ELIRINDNGGTVSLGRVGGVLALSRAFSDFQFKRG----VTYPHRRTKLTN-----------------------ITQNLTYGTPPQEAQVTVEPDVLMHKIDYSKDEFLVLACDGIWDIYNNKQLIHFIKYHLVSGTKLDTIITKLLDHGIAQANSNTGVGFDNMTAIIVVLNRKGETLQDWFNKMKTRLERERGLV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : : . :: . .: : : . : .. : : . : . : . : * . : * : * *: .*. . * :. . : . : : : : . .. . : :* . : . : : **: . : :. : * :. : :.* :: :.* :*:*. **::* . :. : * . . :.: * . : .*. **:*.::*.*. : : ", "identical_positions": 25, "similar_positions": 94, "identity": "3.23%" }, { "cls_id": "homologset.agr.MGI:2444098", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LGW6-1", "uniprot_id": "A0ABK0LGW6_RAT", "id": "A0ABK0LGW6-1", "name": "HEAT repeat-containing protein 5B", "aln": "----------------------------------------MCEVRTSIMELAHSLLLNEEALAQITEAKRPVFIFEWLRFLDKVLVAANKTDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAALYSIGDTYTVFQTLDKCNDIIRSKDDTAA------YLPTKLAAVACVGAFYEKMGRMLGSAFPETVNNLLKSLKSAESQGRSEILMSLRKVLTGLGGAAASSHRDIYKNARSLLTDRSMAVRCAVAKCLLELQNEAVFMWTAELENIATLCFKALENSNYGVRVAVSKLLGTVMATALMPKQATVMRQN--------------VKRATFDEVLELMATGFLRGGSGFLKSGGEMLKVGGSVNREVRVGVTQAYVVFVTTLGGQWLER----SFATFLSHVLDLVSHPRATQTHVDAVYSRRCVSFILRATVGSLLGEKAQIAAAKEICQAIGKQMKAVEAVVNDTSSENKSGAADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLEIVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRCAERLNNLKTSP-----EAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGPSVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDAVRKLMTPIECAMTMMSHIPSVIKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLLGSWLQET---DHKSIEDQLQPN-----------SASGSGALEHDPSSIY-------------------------------LRIPAGEAVPGPLPLG----------------------VSVIDASVALFGVVFPHVSYKHRLQMLD--HFAECVKQAKGVRQQAVQLNIFTAVLSALKGLAENKSTLGPEE---VRKSALTLVMGALDNPNPILRCAAGEALGRMAQVVGEAS---FIARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNAATISTIRSSCLVGCAITQDHS----DSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNAGDKEISGGNVSPFAPGVSSRSDIHCRHQGVNITDTGLEGLLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLT--LCKDVLAASSDMSAATLLSSGK----------DEESEKKDEMDDDAMFTTLGEEDKSKPFVAPRWATRVFAADCLCRIINLCENADQAHFDLALARSAKLRNPKNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVSDLNDLRRVHNLLVSSLDKVQAGKGSPSQ----LYRESATTMEKLAVLKAWAEVYVVAMNIKKEAESKPKRAMKNTD--DDDDDFGTIDELPP---DSLITLVQPELPTLSRLWLAALKDYALLTLP-AEFSSQLPPDGGAFYTPETIDTARLHYRNSWAPILHAVALWLNSTGFTCQESTEATAVSGGQKRSPAVSLNQVPGAMASAKPLPEVNKDRMHLILGVSIQFLCSPRPEEPIEHVTACLQALHTLLGSPYARIHIAEDQLIGVELLSVLHRLLLTWNPPSIQLLVTGVVQQIVRAAQDYLQEKRSALNEEDMEKESCPALGEGGDTGGLIPGKSLVFATMELLMFILVRHMPHLSTK--------------MSDSPSHVATKTHLSEESARLVAATVTILSDLPSLCSPAGCMTILPTILFLIARILKDTAIKSVDNHVSPP----VSAALQGIKSIVTLSMAKTEE-TQKQWTALIRSTLACILEYSQ--PDDCMPAPDEVSTLTAIALFLWSASSEIIGVQSLQNGCMNRFKSALNSCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPLVVGKLKAVERDRPASSTELLAVQEGIKVLETLVALGEEQNR-------VQLLALLVPTLISYLLDENSFASASSISKDLHEFALQNLMHIGPLYPHAFKTVMG--AAPELKARLETAVRASQAS----KAKAAARQPAPATHSAPTIKLKTSFF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C547-1", "uniprot_id": "HTR5B_MOUSE", "id": "Q8C547-1", "name": "HEAT repeat-containing protein 5B", "aln": "------------------------------------------------MELAHSLLLNEEALAQITEAKRPVFIFEWLRFLDKVLVAANKTDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAALYSIGDTYTVFQTLDKCNDIIRSKDDTAA------YLPTKLAAVACVGAFYEKMGRMLGSAFPETVNNLLKSLKSAESQGRSEILMSLQKVLTGLGGAAASSHRDIYKNARSLLTDRSMAVRCAVAKCLLELQNEAVFMWTAELENVATLCFKALENSNYGVRVAVSKLLGTVMATALMPKQATVMRQN--------------VKRATFDEVLELMATGFLRGGSGFLKSGGEMLKVGGSVNREVRVGVTQAYVVFVTTLGGQWLER----SFATFLSHVLDLVSHPRATQTHVDAVYSRRCVSFMLRATVGSLLGEKAQIAAAKEICQAIGKQMKAVEAVVNDTSSENKSGTADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLEIVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRCAERLNNLKTSP-----EAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGPSVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDAIRKLMTPIECAMTMMSHIPSVIKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLLGSWLQET---DHKSIEDQLQPN-----------SASGSGALEHDPSSIY-------------------------------LRIPAGEAVPGPLPLG----------------------VSVIDASVALFGVVFPHVSYKHRLQMLD--HFAECVKQAKGVRQQAVQLNIFTAVLSALKGLAENKSTLGPEE---VRKSALTLVMGALDNPNPILRCAAGEALGRMAQVVGEAS---FIARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNAATISTIRSSCLVGCAITQDHS----DSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNAGDKEISGGNVNPFTPGVSSRSDVHCRHQGVNITDTGLEGLLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLM--LCKDVLAASSDMSAATLLSSGK----------DEESEKKDEMDDDAMFTTLGEEDKSKPFVAPRWATRVFAADCLCRIINLCENSDQAHFDLALARSAKLRNPKNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVSDLNDLRRVHNLLVSSLDTVQAGKGSSSQ----LYRESATTMEKLAVLKAWAEVYVVAMNIKKEAESKPKRAMNNPD--DDDDDYGTIDELPP---DSLITLVQPELPTLSRLWLAALKDYALLTLP-AEFSSQLPPDGGAFYTPETIDTARLHYRNSWAPILHAVALWLNSTGFISQESTEATTVSGVQKRSPAVSLNQVPGAMASAKPLPEVNKDRMHLILGVSIQFLCSPRPEEPIEHVTACLQALHTLLGSPYARIHIAEDQLIGVELLSVLHRLLLTWNPPSIQLLVTGVVQQIVRAAQDYLQEKRNALNEEDMEKESCPTLGEGGDTGGLIPGKSLVFATMELLMFILVRHMPHLSTK--------------MLDSPSHTAMKTQLSEESARLVAATVAILSDLPSLCSPAGCMTILPTILFLIARILKDTAIKSADNQVPPP----VSAALQGIKSIVTLSMAKTED-TQKQWTTLIRSTLACILEYSQ--PDDCMPAPDEVSTLTAIALFLWSASSEIIGVQSLQNGCMNRFKSALNSCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPLVVGKLKAVERHRPASSTELLAVQEGIKVLETLVALGEEQNR-------VQLLALLVPTLISYLLDENSFASASSISKDLHEFALQNLMHIGPLYPHAFKTVMG--AAPELKARLETAVRASQAS----KAKAAARQPAPTTHSTPTIKLKTSFF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2D3-1", "uniprot_id": "HTR5B_HUMAN", "id": "Q9P2D3-1", "name": "HEAT repeat-containing protein 5B", "aln": "------------------------------------------------MELAHSLLLNEEALAQITEAKRPVFIFEWLRFLDKVLVAANKTDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAALYSIGDTFTVFQTLDKCNDIIRNKDDTAA------YLPTKLAAVACVGAFYEKMGRMLGSAFPETVNNLLKSLKSAESQGRSEILMSLQKVLSGLGGAAASSHRDIYKNARSLLTDRSMAVRCAVAKCLLELQNEAVFMWTAELENIATLCFKALENSNYGVRVAVSKLLGTVMATALMPKQATVMRQN--------------VKRATFDEVLELMATGFLRGGSGFLKSGGEMLKVGGSVNREVRVGVTQAYVVFVTTLGGQWLER----SFATFLSHVLDLVSHPRATQTHVEAVYSRRCVSFILRATVGSLLGEKAQIAAAKEICQAIGKQMKAVEAVVNDTSGENKSGAADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLEIVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRCAERLNNLKTSP-----EAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGPSVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDVIRKLMTPIECAMTMMSHIPSVMKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLLGSWLQET---DHKSIEDQLQPN-----------SASGSGALEHDPSSIY-------------------------------LRIPAGEAVPGPLPLG----------------------VSVIDASVALFGVVFPHVSYKHRLQMLD--HFAECVKQAKGVRQQAVQLNIFTAVLSALKGLAENKSTLGPEE---VRKSALTLVMGPLDNPNPILRCAAGEALGRMAQVVGEAT---FIARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNGATTSTIRSSCLVGCAITQDHS----DSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNTGDKESSSANVSPFAPGVSSRTDIHCRHQGVNITETGLEGLLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLM--LCKDVLAASSDMSTATLLSSGK----------DEEAEKKDEMDDDTMFTTLGEEDKSKPFVAPRWATRVFAADCLCRIINLCENADQAHFDLALARSAKLRNPTNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVSDLNDLRRVHNLLVSSLDKVQAGKGSSSQ----LYRESATTMEKLAVLKAWAEVYVVAMNIKKEAESKPKRAIKNTD--DDDDDCGTIDELPP---DSLITLVQPELPTLSRLWLAALKDYALLTLP-AEFSSQLPPDGGAFYTPETIDTARLHYRNSWAPILHAVALWLNSTGFTCSESTEAAAISGLQKRSTSVNLNQASGAVGSAKSLPEINKDRMHLILGVSIQFLCSPRPEEPIEHVTACLQALHTLLDSPYARVHIAEDQLIGVELLSVLHRLLLTWNPSSVQLLVTGVVQQIVRAAQDYLQEKRNTLNEDDMEKEACTVLGEGGDSGGLIPGKSLVFATMELLMFILVRHMPHLSTK--------------VSDSPSHIATKTRLSEESARLVAATVTILSDLPSLCSPAGCMTILPTILFLIARILKDTAIKSADNQVPPP----VSAALQGIKSIVTLSMAKTEAGVQKQWTALIRSTLACILEYSQ--PEDSVPTPDEVSMLTAIALFLWSASNEIIGVQSLQNGCMNRFKNALNSCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPIVVEKLKAVERNRPASNIELLAVQEGIKVLETLVALGEEQNR-------VQLLALLVPTLISYLLDENSFASASSASKDLHEFALQNLMHIGPLYPHAFKTVMG--AAPELKVRLETAVRASQAS----KAKAAARQPAPAIHSAPTIKLKTSFF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ISV1-1", "uniprot_id": "A0A0R4ISV1_DANRE", "id": "A0A0R4ISV1-1", "name": "HEAT repeat-containing protein 5B", "aln": "------------------------------------------------MELAHSLLLNEEALSHITEAKRAVFIFEWLRFLDKVLIAANKVDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAVLYSIGDTFTVFQTLDKCNDIIKSKDDTAA------YLPSKLAAVACVGAFYERMGRMLGSSFPETINNLLKALKSAEAQGRGEILLSLQKVLSGLGGAAASCHRDIYKNTRSMLSDRSMAVRCAVARCLLELQNEAVFIWTTELENVATLCFKALEGSTYDVRVAVSTLLGTVMATALMPKQATVMRQN--------------VKRATLEEVLELMATGFLRGGSGFLKSGGEMLKG-ASVSREVRVGVTQAYVVFVTVLGGQWLER----NFAVFLSHLLELVAHPRATQTHVEAVYSRRCVSFALRATLGGLLGEKAQIAAAKEICLAISKQMRAVEAVVNEQSSENRTGAADVSASQHVMVCALKELGRLVQSLSATASPLIQEPSIGLLETVLSVLLHPSMAARLAAAWCLRCVCVALPHQLTPLLERCADCINTLKNSP-----EAVSGYSFAMAALLGGVHQCPLGVPHSKGKMVVSIAEDLLRSAAQNSRLSLQRTQAGWLLLGALMTLGPSLVRYHLPKMLLLWRNVFPRSQKELEAEKARGDSFSWQVMLEGRAGALCAMRSFVAHCPELLTEDVIRRLMTPIECAMTMMSHIPAVIKVHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLMGSWLQET---DHKSIEDQLQPN-----------SASGSGALEHDPSSIY-------------------------------LRVPAVEAVPGPLPLG----------------------VSVIDASVALFGVVFPHVSFKHRLQMLD--HFAECIKQAKGVRQQAVQLNIFTAVLSALKGLAENKSSLGLEE---VRKSALALVMGALDNSNPILRCAAGEALGRMAQVVGEAS---FIARMAQHSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDATCHEVQTWALHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGALITTVGPELQGNSVSISTIRSSCLVGCAIMQDHS----DSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQMAQREAAEVCEYAMSLARRAGDTKDNS-------------------TTNLNITETGLEGVLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLK--LCKDVLAATTEVGGAVASDSRRKD-------DDEDSEKKDEMDDDIMFTSLGQDEKMKATVAPRWVTRVFAAECLCRIIHLCENADHAHFHLAEARIAKIKNPEADFLVLHLCDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFAAVPDPEFPSHVILEQYQANVGAALRPAFSPDTPSDITAKACQVCSAWIGSGVVSDLNDLRRVHNLLVSSLDKVQTGKSSSSQ----LYSESATTMEKLAVLKAWAEVFVVAMDIKQESRARPVRPPAGED--EDED--EAADVLPP---DSLMVLVQPELPSLSRLWLELLRDYALLTLP-AEFSSQLPADGGAFYTPETIDTARLHYRSSWASVLHAEALWLSSTGFG---ITEDSAASG--------------AAVQPAKHPEELVKDRLHLLLGISIEFLCFPRAEEPIEDVMSCLRAVCTLLDSPIARTHIAEDQLLAVELLNVLHRLLLTRDPSSVQLQVTAVVQKTIHAAQEHLEQRRS--NKGGVNEDGVCVLGEGADSGELLPGKSLVFAAMELLVFILVRHLPQLKEK--------------NTDT--CRRSPQSLSEHSSRLVANSVTALAELPSLCSPAGSMTILPTVLFLITGVLRETAVKTADNSVSAP----VSAALQAIKTILSSTAAHTHA----QWSALVRSSLATVLEDSQ--PSD---SVDEVSFLAAITLFLLSASGDLMSVCVLQKGCIERFTHALNSADPWTQARCCQLLLSILQQPSRSLSVPFIHTLAPLLVEQLKSVERRRVCNAAELQAVQERVRVMETLVNMAEEHNR-------VQLLALLVPTLVSYLLDDSSFSSSSSSSKGLHDFALQSLMHTGPLYPAAFMTVIG--AAPELKTRLEAAIRSKQAHS---RAKSTARQTLPAAPAAPTIKLKTSFF---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KGF6-1", "uniprot_id": "A0A0B4KGF6_DROME", "id": "A0A0B4KGF6-1", "name": "HEAT repeat-containing protein 5A", "aln": "MENLNFARTPQFLRKVISEARRSFINSDHFSASSTRGRSETEEEAISEMELAHTLILNEDALKQLPEHKRPVFELEWLRYLEKALPLVSKAEIKASQKKLVQQLSERIQGAPGPPIRKLIASALATLFSVGDTFMLFDTVNACNDILKNKDDSPS------YLPTKLAAICVLGSMYEKLGRMMGRTYEDTVQILIRTLRNAESQARIEIMHTLEKVSAGMGTAIANVHKDIYKAAKHCLLDRVMAVRVAAARCILKMIYSAPFLYQTELESLGTLCFRAFDGSNYEVRCAVAQLLGTLLAYTQQLAEAATSKKKQGQAVAIQAGKGATQRLVSLDEALGILMSGFLRGGASFLKGTGEIIKGSSGVNREVRVGVTHAYVVFVQFMGSVWLER----QLSTFLAHVLDLVANPKAACSHVDAVYSRKCISFILRSTIGKMLGEKAQSAACKELVHLVAKQMNSIDFNPENAKDSNQ----ETLFSQHLLVCALQELSSLLIGLGTTAQNLLGDQSLQAIDATCAVLVHPCAAARLAAAWCLRCACVAVPGQITPLIDRFVEAIEQMRSSP-----EAMAGYSCALAAILGSVRYSPLGIPHTKGKVVFNCAEELLRSASQNSRMSLHRTQAGWLLIGAIMTLGSPVVKGLLPRMLLLWRNSFPRSNKELESEKARGDAFTWQVTLEGRAGALSVMHSFLLNCPDLLNEDITRRLLTPIESALAMLVNLASVLKSYGTQLKAPAAMVRLRLFETLTLLPANALEASYTHLLRMLVSEFTLSDNAANTTNSLLRTLCHGDDSIILGTWLQET---NHRTIEDQMEPNRKVDGEHLQPNSAAGSGALEHDPCCLYRPRSAQGNGSSSNGSSATSTGGSNGGGGSNIQQISKAQQCPGPLPLG----------------------VAVIDMAVTLYGTIFPKVANKHRLQMLE--HFTECIRQAKSSRQEAVQMNIFTALLCALKNLTDSKTSLGQED---VRKSATALIVASLTSANSTIRCAAGEALGRLAQVVGDSH---FTAELAQNSFDKLKSARDVVTRTGHSHALGCLHRYVGGMGSSQHLSTSVSILLALGQDSASPVVQAWSLYALAQIADSGGPMFRGYVEATLTLCLKLLLTVPHAHVDVHQCVGRVVNALITTVGPELQGGGGAVATMRGSFLCSAALLQSHS----DPLVQAEAIGCLQQLHLFASKSLQLEELVPTLVGMLACNYFILRKASVSCLRQLAHREAKEVCELALTINAEQLP--------------------------DLVITEYGLPGLLFSLLDTETDAEMLRNIHDTLTSMLQMLAADNLSSWLS--LCKNVLTVAVEGGLNDDPAAGEQSKSKEAGGEDDEEDEEEEYADDVTEYRAEENTSTHPAVQPRWPTRVFAAQCVRRIIASCEAASSVHFDLLQAKEQQLIRSRGDYLILHLAELIRMSFMAATSDSDQLRLEGLRTLQEIIDRFANVPEPEFPGHLLLEQFQAQVGAALRPAFAPDTPSHVTAAACEVCSAWIGSGVARDIGDLKRVHQLLVSSLDKLSS-KTNSTQ----LYNESMATLEKLSILKAWAEVYIVAMIGNGKAPASLLNLQSQQSGFQSLTNLETDSDVPDSRGESLLGLVQPELHNLSTHWLSAMKDHALLLLP-AEFQSQLPHDGGAFYTTDTINSSKPHYMTSWPPILYASALWLRDEGFARHLDTSEAAAES----------------NNNQITHGSLSADRFHMIFGICMEALCSMRSSERPRNIVSCLRSLHSIFDSDWARRQLVKDRALTIELCHVLHRQILTRDELLVQLLCVEILKQTIRAAREDLERKRD----DNANSEDGKGGERHGEDDSMQPGSSHVYAVLEVCLCLFVRQIPTMNPTRQGAGGSGLQLDFAYAKMATGSSFFSVLGDENGLLVSSGLQCVEQLMDLCTPKGALAILPTVLYMTTSIVKEIANKSAIDSTILANTCAVKSALQCLRSVCVHKWAKVEE-TTEEWQQLLQSALATIVDLTKTAGDNEERKVDEVTMLLAITVFILHTPASVVATPSLQYPCINHFRQCLQSENLSVKLRCIETTRSIFARAELKTATPYIHALAPRIIESLYAESSKVPTSELELQVTLESIVTVEQLIDLSEPQNRNMNLLQDIQMLTLLVPVLIGFLAEPSRLRTLPKYQRQLHDQALQWLLKIGPKYPQEFKALMG--QTPELRQKLEAAIRSQQQSINIAQKASEAQRNLLAKPQKPTIKLKTDFSNFQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39526-1", "uniprot_id": "LAA1_YEAST", "id": "P39526-1", "name": "AP-1 accessory protein LAA1", "aln": "-----------------------MANRSLKKVIETSSNNGHDLLTWITTNLEKLICLKEVNDNEIQEVKEIHTQLDEFVRYISVLENTDDLELHSVFISLSQLYTISIWRLKDEYPGVVFDSAAFLTNVLCEEDVSIDDGDTDPNQKKKKKKSSTKKKKYIYSPAKDIACTILVQLFENFGSSISSLIPLLFNAIFKNLKKIMEKSKYYHATFMTTLLQLFNAILRNSN-----NDDKILDPATYAKFSKLSKTVFDSISTDEKDFSVTFVSVLIECWTAHFKQTNFIREHSHDIIETIYSRFTEGEIGVYGFAN-------------DETRIFTAKSLAEILFDYYFSKNILTLQEVWSIYVKIFLNCDTRDVESGCFESIIHLINLNLLADNTFLSNSKYLDIVLSLSGVFSSYEVNNRSMNTLSRYLRYFQHMHEVILPHLNDSAKTQMLYYILGCSDTYQSSSKSDSASNFKYSIDAKPETQWLTLLQLDFTYVLISDLGSTFTTEEN-TVKEIRDKLVDLATCEIFTIRVHTVEILKVFLNNCPEYLSETIENSLRALSTDFKSTGKFIFHKNHGHAFIIANLIKGAESDYISYELIMRITVFSTSFIKNNTTSTSSNLYFKGLLCWILLIGLMNYKDEQYLKLQIPQLFLFWKVLLTHTYTYHDEDELYKN-------LEIRNHALTCLLTYLSNT------TIDKEMAKQVSYLLTKCSNFNHSIDLKSKNIDNALLHNENRILQVYLKLEKYINSDFNSSLLILIVKNFSDPNLYTESSSSVLGSLKDIGNRKVSNKDDMESNIVLESSINTLLRQNNGFAFG--LSSKITGDRIVNLSMSSAYKYDESISGSWPSKDYN-----------WYNIFEVEVSKPISPILSLDSLILLYGSGSYSQIDRYAPQVTTSLIDSSMELFSSVFPFLNSKIQYSIMETLNLSMFSKMTTPLRSVAVAANVCSALHNALRIMQENNLELDYSVGQLIIESIKKIQFFNDIFLTKIKADCVGLLTAAIARTLGDEERQKFLTEQSRIFIKNVADMDEPYLRMFHVLSLATIFKYN---SQYANFEEYFDVIFALMRD-PHPVVHSWSLKAMHILLEKHLVIDLKTAALLLSSMEELLVQDKYGIYGRSTLRCNYNRDFNSHVAIGEISRTLTETVGPNFLELNTKVLDSFRNITLSMLISNNILNSITSIKMFENIATFKMKNILNYEIFILASKSIIKSSIVTGIGSSYFDTTFTGSNELISRTSSLKGAFEN---------------------FDLLTLLYKLQMEEFFMKEMENLSWRYLALFPNSGSVKNYFTEWILHTFKRDNHWFDKLYSIFNMSLGRLFQSYN----------RDVSALLEVNGLKKSSEKEIKGEEEESIANVNQLTDTDAGGLDSENLQWKSRQIILNLILMLCLESEKYENLLLALSNKIADLIKISFRGSTVRNEGMKLTGLHILNFVLKNYSTMRDPQVPGSSILEQQEAQITSALMPAFSKGSSPTVMSFAITVAAEVLASNIMPPD-KLGRISQLLIDLLGNFKDPNSGIRIGEAIIVTPKAKRKIELAVLDAWAEVVQRSITSSN---------------------------------DALFSFTRKYWSILVPLWIISLREYMMIKYNDNDSTVQVKNDSKENSLIEPRSTKIELYEPVWLNFVEALGCTLDSDVQVILASLND-----------------------------EELEYFLFILFSQCLEAIVKNIDDHSVK--MQVLPALHNVLKSNLCIKSIFEDDIIT-EVVEIMDRLISTGDSKEEFLLVDIISDLIIGYSKCNAT------------------------PETFLQDIDKLYELLRLLMTIISERLPFIKYN---------------VLTSEEDDNEIKISPTDISLLKKTFIAFESNISNFDNMFKVDLYSCLLFIIG-KIYECSHREVIIPIILP-------LFKALVKALTESEDEKNIVLLEIFYGSIKDVIYHKLDSKN---------------KVATILILLSNGYSKLSFQELN-QCANILSEALN--NPATQPIALQGFKRIISN---IFKYPLLQYFMKLVIKRFFQDIQTNDSLSQASIKTKLIIQFSEEVIKQDHQKAS------------LSIALCLSFFAAYH-----SAYTEKIDNEVASGIVALAKLDKNSFKEAISSTISPQQKAIIGSVMEAYVKS-----------QSLGSVEEAFQLKSFD------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : : *:* .: * *. :: : ..* ... ::: .* : : * . :: . : : :: : : :.*..:.: * *:* * : ::*.:* :. .: ::: *:. :.: : .: :. . : * * :: ::. : . : .: *: * .. :* :: *: : .. : : * : .: . : : :. :.* : .: :: :. * . : :* :*.* . : : :: : :: :* . : * : : :. . . .: .. : :* : : *. *: .*.:* : : : *: :. *: * :: ::. :. .*. . *:: :* :: ... :. *.. : .::: .*.: :: . **:* : . :: :*:::*:*: :.:: . : :: : ** * ** : ::: : :.: . :. :: :: :. . ::. . . *: : * . . ** :* :*: .: ::::.*:* :* . .: : .. *: . :*: :. * . :*. :: . .. * .: : . *.*. .::** :: *:. :** : * : .::: ::: : :. *. ** *: :*: **: : :.: *. . : :* : . . ..* . :*:.:*: * :. :: :.:: . : * * :*. :.:* .. ::. ..:::** :* . *::*:* :: : :. : . *: **: . . : : *. . : :. . . : :.. . *:. :..: .:::* . : . : .. ::: : *: : . : .: :: .: * * : : *. :. . : . :: * : : * : . : . : : . : . .. . . * . *. . : . :: * . : . * ::.:**:::* .:* .: ::: **: *: ::..:: : :*:.*. :*** :*:: :** ***: .:.. : : * *.: :.*.: .* *: :**:. *.... : . : . :*::*.***** :: . ::*: :.: * *: :::: :: : *: *. :. .: * * .: * . * . . . :.:::. .:: : .. . * :: .:: * . : :* : *: ::.* : * : * : . : :: : . . :: :.: : :: .::* :. . :. . *: . . . . : : . :*:: : : : : . . :: : . . . . : ::. : :: .: * ::: . :. *: * : : .*: : .: . : :: . * :: : :: : . : * :: . : * :. :.:: . . :.: . . :: . * :. :*: : : :.:.: : : :* ", "identical_positions": 177, "similar_positions": 664, "identity": "7.75%" }, { "cls_id": "homologset.agr.MGI:2444103", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UMR0-1", "uniprot_id": "ANR27_MOUSE", "id": "Q3UMR0-1", "name": "Ankyrin repeat domain-containing protein 27", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MALYDEDLLKNPFYLALQKWRPDLCSKVAQIHGIVLVPCRGSLPGSVQASCQFESYVLVPTEGHFQTLDGKAVVIEGNRIKLGAGFACLLSVPILFEETFYNEKEESFSILCIAHPLERRETSEEPSAPADPFSLKTIEDVREFLGRHSEKFDKNIASFHRTFRECERKSLRHHIDSVNALYTKCLQQLLRDSHLKVLAKQEAQMNLMKQAVEMYVHHDIYDLIFKYVGTMEASEDAAFNKITRSLQDLQQKDIGVKPEFSFNIPRAKRELGQLNKCTSPQQKLLCLRKVVQLMTQSPSQRVNLETMCADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSSAKDELGYCLTSVEAAIEYIRQGSLSTKTPDAEGFGDRLFLKQRMNLLSQMTSTPIDCLFKHIASGNQKEVERLLSQDDQDKDAMQKMCHPLCSCEDCEKLISGRLNDPSVVTPFSRDDRGQTPLHVAALCGQASLIDFLVSKGAVVNATDYHGSTPLHLACQKGFQSVTLLLLHYKASTEVQDNNGNTPLHLACTYGQEDCVKALVYYDVQACRLDIGNEKGDTALHIAARWGYEGIIETLLQNGAPTAVQNRLKETPLKCALNSKILSIMEAHHLSSDRRPRPSEVPAQSPTRSVDSISQGSSTSSFSSISVSFRQEEVKKDYREVEKLLRAVADGDLEMVRYLLEWTEDDLDDVEDAISTVDLEFCHPLCQCPKCAPAQK-LARISANGLSVNVTNQDGFSPLHMAALHGRTDLVPLLLKHGAYSGARNTSQAVPLHLACQQGHFQVAKCLLDSNAKPNKKDLSGNTPLICACSAGHHEVAALLLQHGASINACNNKGNTALHEAVMGRHTLVVELLLFYGASVDILNKRQYTAADCAEQDSKIMELLQVVPGCVASLDS----VEEADHEGYVTVEIRRKWNPKMYNLPEEPLRRQFCLINPGGRFQERT-SRETMGRDRSVPDLAGRSLQEPEKQRVTGKQSDLSDLSRYQTSEEGNKGLPERPVSRQAAPGHRPMVRRHTVNDAAILQVPEVTVHLTT-HEASVPQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZNY3-1", "uniprot_id": "A0A8I5ZNY3_RAT", "id": "A0A8I5ZNY3-1", "name": "Ankyrin repeat domain-containing protein 27", "aln": "MHLFLGLHGRPESPGAGTWGSGQNPGHVAWKVFRWPNWILREEAVCTGLGQLIKFPRGLKVERVSLPALHVARSSRPVGMENSGTQRRSITQSLFSFLVGNGLRRCARAGRYPSSLSFSCRGGGHSVEGGSGSKLTLTRSKGLREAHVDPPEVHMALYDEDLLRNPFYLALQKWRPDLCSKVAQIHGIVLVPCRGSLPSNVQASCQFESYVLVPMEGHFQTLDGKAVLIEGNRVKLGAGFACLLSVPILFEETFYNEKEESFSILCIAHPLEKRETSEEPSAPSDPFSLKTIKDVREFLGRHSERFDKHIASFHRTFRECERKSLRHLIDSVNALYTKCLQQLLRDSHLKVLAKQEAQMNLMKQAVEMYVHHDIYDLIFKYVGTMEASEDAAFNKITRSLQDLQQKDIGVKPEFSFNIPRAKRELGQLNKCTSPQQKLLCLRKVVQLMTQSPSQRVNLETVCADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSSPKDELGYCLTSVEAAIEYIRQGSLSAQPPDAEGFGDRLFLKQRMNLLSQMSSTPIDCLFKHIASGNQKEVERLLSQDDQDKDAMQKMCHPLCSCEDCEKLVSGRLNDPSVVTPFSRDDRGQTPLHVAALCGQASLIDFLVSKGAVVNATDYHGSTPLHLACQKGFQSVTLLLLHYKANTEVQDNNGNTPLHLACTYGQEDCVKALVYYDVQACRLDIGNEKGDTALHIAARWGYEGIIETLLQNGAPTAIQNRLKETPLKCALNSKILSAMEAYHLSSDRRPKPSEVPAPSPTRSADSISQGSSTSSFSSVSVSFRPEEVKKDYREVEKLLRAVADGDLEMVRYLLEWTEDDLDDMDEAISTVDLEFCHPLCQCPKCAPAQKKLARIPANGLSVNVTNQDGFSPLHMAALHGRTDLVPLLLKHGAYSGARNTSQAVPLHLACQQGHFQVAKCLLDSNAKPNKRDLSGNTPLICACSAGHHEVAALLLQHGAAINACNNKGNTALHEAVMGRHVLVVELLLFYGASVDILNKRQYTAVDCAEQDSKIMELLQVVPSCVAASPNNVVVVQETEHEDYVTVEIRKKWNPKMYNLPEEPFRRQFCLINPGGRFQERTKSWETMGRDRSVPDLTG-GLQEPEKQRVTGKQNDLSDQSRCQTSEEGNKGLPGRPVPRQAVPGHRPMVRRHTVNDAAILQVPEVTGHLTT-QEAGVSRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96NW4-1", "uniprot_id": "ANR27_HUMAN", "id": "Q96NW4-1", "name": "Ankyrin repeat domain-containing protein 27", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MALYDEDLLKNPFYLALQKCRPDLCSKVAQIHGIVLVPCKGSLSSSIQSTCQFESYILIPVEEHFQTLNGKDVFIQGNRIKLGAGFACLLSVPILFEETFYNEKEESFSILCIAHPLEKRESSEEPLAPSDPFSLKTIEDVREFLGRHSERFDRNIASFHRTFRECERKSLRHHIDSANALYTKCLQQLLRDSHLKMLAKQEAQMNLMKQAVEIYVHHEIYNLIFKYVGTMEASEDAAFNKITRSLQDLQQKDIGVKPEFSFNIPRAKRELAQLNKCTSPQQKLVCLRKVVQLITQSPSQRVNLETMCADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSLAKDELGYCLTSFEAAIEYIRQGSLSAKPPESEGFGDRLFLKQRMSLLSQMTSSPTDCLFKHIASGNQKEVERLLSQEDHDKDTVQKMCHPLCFCDDCEKLVSGRLNDPSVVTPFSRDDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKETPLKCALNSKILSVMEAYHLSFERRQKSSEAPVQSPQRSVDSISQESSTSSFSSMSASSRQEETKKDYREVEKLLRAVADGDLEMVRYLLEWTEEDLEDAEDTVSAADPEFCHPLCQCPKCAPAQKRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDD----VAETDRKEYVTVKIRKKWNSKLYDLPDEPFTRQFYFVHSAGQFKGKT-SREIMARDRSVPNLTEGSLHEPGRQSVTLRQNNLPAQSGSHAAEKGNSDWPERPGLTQTGPGHRRMLRRHTVEDAVVSQGPEAAGPLSTPQEVSASRS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********:********* *******************:***...:*::******:*:* * *****:** *.*:***:**************************************:**:**** **:********:***********:**::****************** ***.******************:****************:****:**:*************************************************.************:********:************:*********************************** .**********.*************::.*::*************.*****:*:* *********************:*:***::******** *:*****:*******************:*******:********:******:********:**********:************.:******************:************::************.*********:*:*********.* :******************* ***:*** :** :.**.*. ** **.***** ********:*.* * **.******************************:**:* ::::*:.* ***************** **::.*.**.****.*** ****:******:**:******** :****:.****************.************:********* ***.****:.********:***.************: :*.:******::****::***** **.*****:***********.***: . * *:::: ****:**:***.*:*:**:**: *** :::..*:*: :* * * *.******:*: .*:** :* ** :*.:*. * :::*:**.. * ** *: **** *:*****:**.: * **.: *:* :*....:*", "identical_positions": 833, "similar_positions": 161, "identity": "68.9%" }, { "cls_id": "homologset.agr.MGI:2444110", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TSX5-1", "uniprot_id": "SMS1_RAT", "id": "Q7TSX5-1", "name": "Phosphatidylcholine:ceramide cholinephosphotransferase 1", "aln": "MLSASTMKEVVYWSPKKVADWLLENAMPEYCEPLGHFTGQDLINLTQEDFTKPPLCRVSSDNGQRLLDMIETLKMEHHIEAHKNGHANGHLSIGVDIPNPDGSFSIKIKPNGMPNGFRKEMIKIPMPEPERSQYPMEWGKTLLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPDTFFDHFNRVQWAFSICEINGMILVGLWLFQWLLLKYKSIISRRFFCIVGTLYLYRCITMYVTTLPVPGMHFNCSPKLFGDWEAQVRRIMKLIAGGGLSITGSHNMCGDYLYSGHTVMLTLTYLFIKEYSPRRLWWYHWICWLLSVVGIFCILLAHDHYTVDVVVAYYITTRLFWWYHTMANQQVLKEASQMNLLARVWWYRPFQYFEKNVQGIVPRSYHWPLPWPVVHLSRQVKYSRLVNDT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCQ6-1", "uniprot_id": "SMS1_MOUSE", "id": "Q8VCQ6-1", "name": "Phosphatidylcholine:ceramide cholinephosphotransferase 1", "aln": "MLSARTMKEVVYWSPKKVADWLLENAMPEYCEPLEHFTGQDLINLTQEDFKKPPLYRVSSDNGQRLLDMIETLKMEHHMEAHKNGHANGHLSIGVDIPNPDGSFSIKTKPNGMPNGFRKEMIKIPMPEPERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPDTFFDHFNRVQWAFSICEINGMILVGLWLFQWLLLKYKSIISRRFFCIVGTLYLYRCITMYVTTLPVPGMHFNCSPKLFGDWEAQVRRIMKLIAGGGLSITGSHNMCGDYLYSGHTVMLTLTYLFIKEYSPRRLWWYHWICWLLSVVGIFCILLAHDHYTVDVVVAYYITTRLFWWYHTMANQQVLKEASQMNLLARVWWYRPFQYFEKNVQGIVPRSYHWPFPWPVVHLSRQVKYSRLVNDT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VZ5-1", "uniprot_id": "SMS1_HUMAN", "id": "Q86VZ5-1", "name": "Phosphatidylcholine:ceramide cholinephosphotransferase 1", "aln": "------MKEVVYWSPKKVADWLLENAMPEYCEPLEHFTGQDLINLTQEDFKKPPLCRVSSDNGQRLLDMIETLKMEHHLEAHKNGHANGHLNIGVDIPTPDGSFSIKIKPNGMPNGYRKEMIKIPMPELERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPDTFFDHFNRVQWAFSICEINGMILVGLWLIQWLLLKYKSIISRRFFCIVGTLYLYRCITMYVTTLPVPGMHFNCSPKLFGDWEAQLRRIMKLIAGGGLSITGSHNMCGDYLYSGHTVMLTLTYLFIKEYSPRRLWWYHWICWLLSVVGIFCILLAHDHYTVDVVVAYYITTRLFWWYHTMANQQVLKEASQMNLLARVWWYRPFQYFEKNVQGIVPRSYHWPFPWPVVHLSRQVKYSRLVNDT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **************************** ***************.**** **********************:************.******.******** ********:*********** ************:***************************************************************:*******************************************************:****************************************************************************************************************************************:********************", "identical_positions": 400, "similar_positions": 9, "identity": "95.47%" }, { "cls_id": "homologset.agr.MGI:2444113", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C8N6-1", "uniprot_id": "NEMP2_RAT", "id": "P0C8N6-1", "name": "Nuclear envelope integral membrane protein 2", "aln": "MPPGS--WWLVLWLPPLATLPAGAVPQEEAAMSVPRCKSLKETDLIKTSVSDCYCYNQHSQIEWTYMWSTVQVTVTSPGLLSIVYITGRHTCQHTETILSFLKCVTHNFWTAEEAKEVTIVFSPYGETVCFSVKPVGSLLTYAVSVNRNVVDFRLFLVFATGIFLFFYAKTLSQSPVFYYSSGTVLGILMTLVFVLLMTKKHIPKYSTFGALMIGCWFASVYVLCQLMENLKWLWCGNRIYVLGYVLVVGLCSFSACYSRGPPADEGSRDLLMWALRFLSLVLVYTGMAISQFAYAVMILLLLS----WTRHYLLRAFSCLRWKVRQWFATRALVVRYLTDDEYREQAEAETASALEELRQACCRPDFPSWLAVSRLQAPKKFAEFVLGASHLSPEEVSTHEK--QYGLGGAFLEEQLFSLQTESLPAS---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CB65-1", "uniprot_id": "NEMP2_MOUSE", "id": "Q8CB65-1", "name": "Nuclear envelope integral membrane protein 2", "aln": "MLPRL--WWLVLWLQPLATLPASAVHDEEAAMSVPRCKSLKETDLIKTSVSDCYCYNQHSQIQWTYMWSTVQVTVTSPGLLNIVYITGSHNCQHTESILSFIKCVTHNFWAPEEAEEITIVFSPYGETVCFSVKPVGRLLPYIVSVSRNIVDFKLFLVFVTGIFLFLYAKTLSQSPVFYYSSGTVLGILMTLVFVLLMAKKHIPKYSTFGALMIGCWFASVYVLCQLMEDLKWLWYGNRMYILGYVVVVGLCSFAACYSHGPLADEGSRDLLMWTLRLFSLALVYTGVAAPQFAYAVLIVLLFS----WSLHYLLRAFSYLRWKMRPWFTAEPQVARYLTDDEYREQAEAATARALEELRQACCRPDFPSWLAVSRLQAPKKFAEFVLGASHLSPEEVSTHEK--QYGLGGAFLEEQLFSLQTDSLPAS---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFY4-1", "uniprot_id": "NEMP2_HUMAN", "id": "A6NFY4-1", "name": "Nuclear envelope integral membrane protein 2", "aln": "MGPRQGRWWLLLWLPPLATLPVRG-EAAAAALSVRRCKALKEKDLIRTSESDCYCYNQNSQVEWKYIWSTMQVKITSPGLFRIVYIAERHNCQYPENILSFIKCVIHNFWIPKESNEITIIINPYRETVCFSVEPVKKIFNYMIHVNRNIMDFKLFLVFVAGVFLFFYARTLSQSPTFYYSSGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVGCWFASVYIVCQLMEDLKWLWYENRIYVLGYVLIVGFFSFVVCYKHGPLADDRSRSLLMWMLRLLSLVLVYAGVAVPQFAYAAIILLMSS----WSLHYPLRACSYMRWKMEQWFTSKELVVKYLTEDEYREQADAETNSALEELRRACRKPDFPSWLVVSRLHTPSKFADFVLGGSHLSPEEISLHEE--QYGLGGAFLEEQLFNPSTA--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QYC4-1", "uniprot_id": "NEMP2_DANRE", "id": "F1QYC4-1", "name": "Nuclear envelope integral membrane protein 2", "aln": "-MEKLAAFILVLTLLCAYWQSAEG----IREYSYADCTDVKGDSAHRYSGSRCFCYSPGTVIKWKDIWSTFKVNVSSNVDVVVVFPMETINCHHPDDLLTVMNCFVEHYWPSTVQRETSLEIPLVDVDICFMIKSPRSNTEYTLHVSNKRLNRMCFLLFVCGLILFFGARNICRSSLFFYTTGVSLGIIATFVFLTLLLRNFVPKRGLFLVLLGAGSGLSYMGIQRVLNEWDDIVTEHWMELLAYVLISGLFSFAVCYKHGPITNKHTLNFMTCSMQAVGIVLLYYGITFPPAYFVLVAVLLCWKILPLAWSLLMGICSLFYSFLALFRRRRRPTVRLLTEEEYREQGEIHTRASLDELREYCNRPGFPAWETVLRLRSPQRFAEFLRQGSHITQEEHQNHEN--HYGLGGAYYENVIFNNSSSSDTQSHREEAEDNSEDEIVGNSPPVLNNLPSPTIYPPTICPYPPVTYTPQPEPLDPEDQDFF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXD6-1", "uniprot_id": "NEMP_DROME", "id": "Q9VXD6-1", "name": "Nuclear envelope integral membrane protein", "aln": "-MHSAGLLMLTVAGYFTSGIPGNTASSDVAYLTPGTYINLSEN-ILGLQTLRTFCYP-GKRLTVSSLFETVEFVLAIGSDD-----YSQYGGKTPEEVLQHYKDKQSLFSITLFAQKRQLLQLSPFEQQCIGISSRQ---AYTVILNSIPLDLWRLAQFAVGILILFSARRLAKNSVFYYLVGIVIGICASLLVVIYLAAKLFPRRTMMYGVLIGGWTIGFYVIKQLADNLRLILITYRDHVLGYLVITGLISFLICYRIGPPKNPRSQTIVMWVLQAIGAVMAYFSSWHTSAVIFIMVLVFVA------HYFPISWTNQIKFMYRRRFPLKR---RMLTQEEYEQQTAVETSKSLADLRKYVNSPECKQWAVMGKLRDPLRFASFANGAPHLDDEEIEDHSRTIEESMDAAPEEESVEEPEEDKPAELLPLPNSQFRYQQAARNSEPEPESESDDSEEEEFFEQEVDLRQVVQ------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . : :. . :** . : . ::.*.:. :: : .: :* : : . .: : *: :.. * : :. :: : *. *::::: *: :.:.. *:* * :*: :::.: : . .*: : :: . . : :: :: : :*.*::: *: ** ** ** : : :: :: .. .: * . . : ::: : . : . : **::**.:* * :* :**. * * .: :*: * :**.* ..*: ** . *.. . .:..* *: : . . ", "identical_positions": 47, "similar_positions": 128, "identity": "9.67%" }, { "cls_id": "homologset.agr.MGI:2444114", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q498S6-1", "uniprot_id": "ZCHC2_RAT", "id": "Q498S6-1", "name": "Zinc finger CCHC domain-containing protein 2", "aln": "MLRMKLPPKSTHPSEPPPDAEEPEADARPGAKAPPRRRRDCRPPPPPP--TGLPRGPPPPPPSPPRGLEPPVASGPTAGAGMPGGGG-HAAALREQERVYEWFGLVLGSAQRLEFLCGLLDLCNPLELRFLGSCLEDLARKDYHYLRDSEAKANGLSDPGS------LADFREPAVRSRLIVYLALLGSENREAAGRLHRLLPQVDAVLRSLRATRVEGSRGSVEDEPG--GDDEQDAEKDGPGPEGGGCAKLGTGGGLGFRAQEELLLLFTMASLHPAFSFHQRVTLREHLERLRSALRVEPEDAEVE--PSNFAGSRAQNDSACGDYIQSNETGLVEQAQIPQDGLTVAPHRAQREAVHIEKIMLKGVQRRRADKYWEYTFKVNWSDLSVTTVTKTHQELQEFLLKLPKEFSSESFDKTILKALNQGSLRREERRHPDLEPILRQLFSTSPQAFLQSHKVRSFFRSISSESQHSFNNLQSSLKTSKILEHLKEDSSEASSQEEDVLQHTIIHKKHAGKSPAGN-VATSCALLEGLTMQYAEQNGVVDWRNQGCAAIQHSEHCVSSADQLSAEKRSLSSVNKKKGKPQVEKEKIKKTENRLSSRINGIRLSAPQHAHGSTVKDMNLDVGSGHDTCGETSSESYSSPSSPRHDGRESLESEEEKDRDTDSNSEDSGNPSSARFAGHGSVTQTVSVQPPADTVSLGTENGNLLEAPLTSHKYPHIPFMPTLPCVMHNGAQKSEVVIPSPKSADGKAVGVLVPNPVAISTMMESTNAAPVGILGP-AASGESEKHLELLASPLPIPSPFLPHSSAPALQLTLQSLKLQPPQGASENCPVNIPQQAATRLSIGSPNTALIPVHNPGAFPGSPVAATDPITKSASQVVGLNQMVPQIEGNTGTVPQPNNVKVVLPAAGLSAAQPPASYTFPGSPLAASVLPTQNSTVLN-TATSAQPASTGISPAQSTVPPAVPTHTPGPAPSPSPALTHSTAQSDSTSYISAVGNTNANSTIVPPQPLG--PCGSCGRRCSCGTNGNLQLNSYYYPNPMPGPMYR--LPSFFTLPSICNGSYLNQAHQSNGNQLPFFLPQTPYANGLVHDP--VMGSQASYGMQQMAGFGRLYPVYPAPNVVANTSGSGPKKNG----SVSCYNCGVSGHYAQDCKQSSMEANQQGTYRLRYAPPLPPSNDTLDSAD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZB8-1", "uniprot_id": "ZCHC2_MOUSE", "id": "Q69ZB8-1", "name": "Zinc finger CCHC domain-containing protein 2", "aln": "MLRMKLPPKSTHPSEPPPDAEEPEADARPGAKAPLRRRRDCRPPPPP---TGLPRGPPPPP-SPPRGLEPPVASGPTAGAGMPGGGG-HAAALREQERVYEWFGLVLGSAQRLEFMCGLLDLCNPLELRFLGSCLEDLARKDYHYLRDSEAKANGLSDPGS------LADFREPAVRSRLIVYLALLGSENREAAGRLHRLLPQVDAVLRSLRATRAEGSRGSVEDEPS--GDGEQDAEKDGPGPEGSGCAKLGTGGGLGFRAQEELLLLFTMASLHPAFSFHQRVTLREHLERLRSALRVEPEDAEVE--PSNFAGSRAQNDSACGDYIQSNETGLVEQAQIPPDGLTVAPHRAQREAVHIEKIMLKGVQRKRADKYWEYTFKVNWSDLSVTTVTKTHQELQEFLLKLPKEFSSESFDKTILKALNQGSLRREERRHPDLEPILRQLFSTSPQAFLQSHKVRSFFRSISSESQHNFNNLQSSLKTSKILEHLKEDSSEASSQEEDVLQHTIIHKKHAGKSPALN-VATSCSPLDGLTMQYAEQNGIVDWRNQGCAAIQHSEHCVSSADQHSAEKRSLSSGNKKKGKPQVEKEKVKKTEDRLNSRINGIRLSAPQHVHGSTVKDMNLDIGSGHDTCGETSSESYSSPSSPRHDGRESLESEEEKDRDSDSNSEDSVNPSSARFSGYGSVAQTIAVKPPAETVSLGTEDGNLLEAALTSHKYPHIPFMPTLHCVTHNGAQKSQVVIPSPKSADGKTLGMLVPNAVAISAVMESSNSAPVGILGP-AASGESEKHLELLASPLPLPSTFLPHSSAPALQLTLQSLKLQPPQGSSDSCPVSIPPQPTGSLSIGSPNTAFIPVHNPGSFPGSPVATTDPITKSAPQVVGLNQMVPQIEGNTGTVPQPSNVKVVLPAAGLSAAQPPASFPFPGSPQAASALPTQNSSALN-AATSAQPASTGISPSQSTVPPAVPTHTPGPAPSPSPALTHSTAQSDSTSYISAVGNTNANGTIVPPQQMG--PCGSCGRRCSCGTNGNLQLNSYYYPNPMPGPMYR--LPSFFTLPSICNGSYLNQAHQSNGNQLPFFLPQTPYANGLVHDP--VMGSQASYGMQQMAGFGRLYPVYPAPNVVANTSGSGPKKNG----NVSCYNCGVSGHYAQDCKQSSMEANQQGTYRLRYAPPLPPSNDTLDSAD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0B9-1", "uniprot_id": "ZCHC2_HUMAN", "id": "Q9C0B9-1", "name": "Zinc finger CCHC domain-containing protein 2", "aln": "MLRMKLPLKPTHPAEPPPEAEEPEADARPGAKAPSRRRRDCRPPPPPPPPAGPSRGPLPPP-PPPRGLGPPVAGGAAAGAGMPGGGGGPSAALREQERVYEWFGLVLGSAQRLEFMCGLLDLCNPLELRFLGSCLEDLARKDYHYLRDSEAKANGLSDPGP------LADFREPAVRSRLIVYLALLGSENREAAGRLHRLLPQVDSVLKSLRAARGEGSRGGAEDERGEDGDGEQDAEKDGSGPEG-GIVEPRVGGGLGSRAQEELLLLFTMASLHPAFSFHQRVTLREHLERLRAALRGGPEDAEVEVEPCKFAGPRAQNNSAHGDYMQNNESSLIEQAPIPQDGLTVAPHRAQREAVHIEKIMLKGVQRKRADKYWEYTFKVNWSDLSVTTVTKTHQELQEFLLKLPKELSSETFDKTILRALNQGSLKREERRHPDLEPILRQLFSSSSQAFLQSQKVHSFFQSISSDSLHSINNLQSSLKTSKILEHLKEDSSEASSQEEDVLQHAIIHKKHTGKSPIVNNIGTSCSPLDGLTMQYSEQNGIVDWRKQSCTTIQHPEHCVTSADQHSAEKRSLSSINKKKGKPQTEKEKIKKTDNRLNSRINGIRLSTPQHAHGGTVKDVNLDIGSGHDTCGETSSESYSSPSSPRHDGRESFESEEEKDRDTDSNSEDSGNPSTTRFTGYGSVNQTVTVKPPVQIASLGNENGNLLEDPLNSPKYQHISFMPTLHCVMHNGAQKSEVVVPAPKPADGKTIGMLVPSPVAISAIRESANSTPVGILGPTACTGESEKHLELLASPLPIPSTFLPHSSTPALHLTVQRLKLPPPQGSSESCTVNIPQQPPGSLSIASPNTAFIPIHNPGSFPGSPVATTDPITKSASQVVGLNQMVPQIEGNTGTVPQPTNVKVVLPAAGLSAAQPPASYPLPGSPLAAGVLPSQNSSVLSTAATSPQPASAGISQAQATVPPAVPTHTPGPAPSPSPALTHSTAQSDSTSYISAVGNTNANGTVVPPQQMGSGPCGSCGRRCSCGTNGNLQLNSYYYPNPMPGPMYR--VPSFFTLPSICNGSYLNQAHQSNGNQLPFFLPQTPYANGLVHDP--VMGSQANYGMQQMAGFGRFYPVYPAPNVVANTSGSGPKKNG----NVSCYNCGVSGHYAQDCKQSSMEANQQGTYRLRYAPPLPPSNDTLDSAD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P861-1", "uniprot_id": "A0A8M9P861_DANRE", "id": "A0A8M9P861-1", "name": "", "aln": "MMKMKLR--------------------------------------------------------AAGGENYRCDLNSVNGADRESGIG---AAQLDKEAVFEWFGLQLNPAGRVELLCGLLHMCQPLELRFLGACLEDLARRDFTVLRDFEIRANSPADLEG------LVDVSDPVVLSKLLVYLSLLGSKSRECACILFRTLSRMDVGMYGALPEP---------------------------------------------ETVDQLRLLFTMGSLHPAFSFYQREELRAQLDRLQRWSQFSR------------PGFLCPHREDDGDWTLCSNAN------------PHLSSTSQREVVHIEKIILKEISVGGDGR--HYSFEVKWSDSSSSAVTKSHRELEDFLLKLPKEQSPGGFEKGIVKLLSRG----DQCESRDLERNLREKFLSLSQDVLRRCDISRFFLSDASVLPCSHCTSAPVARIHQPERGFSEDCSETSSLEEDVEAYNIRAAGLSNQRSECQ------------RRGNCEQNGERVWKKE-----------NELEQNCTNDRRIFTAGQKNKGRSAGKRDRVRRVTAVKTS-------NGIQKPSAALMINQAACKDAGRDRYGDTSSESSNSVPSS------PVHQKSLEDQDTESQSDNS--------------------------------------------------------------AQEPTEKTQPTKGVGGKAVAMVNPLVAEPQNVPQTPS-------------------VVELALTACLPYSLQYNTTQRDAGQGQITITIPLAQNPGTSSSGTQPQQQPPLGAFSVLSAGQCPLQPANTTTANSAIKTNPKAS---------------------------------------------------------------------ITASGPSSSCSGQVPIACPTSVPTHTPGPAPMPAPAVTHSTAPSDSLSYINSSSLPVTPLASGTQQAGG---CNTCGCRGTCGGNGAHQTHSYFLPPQPARQMFGPPPPPFFHLPPSLCNSFAAQGHQNNGTPLPFYAHSGPPAAFLHAHSDHLLASQAGYSLPQMTPFHRFYPPVFPP-VGLMSGGNNLKKTN----NVSCYNCGMSGHYAQDCKQPSIDAGLTGGYRLKYVAPN--SSEALDKND----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ08-1", "uniprot_id": "Q9VJ08_DROME", "id": "Q9VJ08-1", "name": "CCHC-type domain-containing protein", "aln": "--------------------------------------------------------------------------------------------MICKQDVLQWF-EKLESYNRIETMYALLTACLPFELRFLGTLLEEQGRCDSETLRGMELRANNPHELAADMVNCQKGDPTDRKIRRKMALYLALIRACNRNCVSEIYRTLECWGECDFSCINDQ---------------------------------------------DTLLELLLVYTMAAIHPVFSMEEQKKIFGILAKIKENKLVAERFAPQMQRQTQTPVLQHPHPPSPHDLVIQQQPP----------HVIHQIPGPQQAPPHPQHPQMVQVLQTPQGN-IPMIFPQHFQKLLPSSDGTHQISVDGMPHLMQPNITIPADTSAIISHQNTG----WTMRHYVPQPPHQQPALQQQQPQSLDHQVPPASSPMLSQQSSPSSSRTTSPQRDRSLINVPLQAQQQPHQQQQMRGMSQRMADQKNTR--------------------------------------------RPSAETTPPPTSIGGEQQHDSVNEGGSSNSSGTSLHRLIRNGFPRLGHNHRVKANTFIPQHQQQQQQHHFQNPNYNMN------------VMMQSMNINDDGSGSMMNSMN-------------------------------------------------------------STKSAATTGSESGSSNGSCGDLSPSETPTP-------------------------TQLSLPLHNSVDAGMGMITTVLPTGLGNYQPKPHHFSYKQQQQQMNLQQRLNGRNGMDKTYQQVYTTGTPSIVSDAQTISSASLQQ------------------------------------------------------------------------QQPQTLLISQSPVSTPTTTVLLQP---QQPPPTTYNTSYPYHQRGPPPPQQTIFQAHSAPPPQTVR------GGFRYPMG------------PPHNGELIYPTFHTSLAFLPMTAGGTPTAVTPAQLQSTAAVVSTNAVSVQTVPTPQQQQVPSTTPYSALTVCPITGAGGGGTAPKVISCYNCGSQTHSGRECQEASMEDVTRSASYKLDYSETSMDSSATGDHHKDVGSVQINSTATAGTVTSTVK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * :** * . *:* : .** * *:******: **: .* * **. * :**. : * : : :: :**:*: : .*:.. :.* * . . : :* *::**.::**.**: :: : * ::: . : * .:. .*: * :: : : .. * ::.. :: . : .:: : : : : . *: . * . : :: * .: . * . . : : . :..: . :::: . : : : . :::.. .. . . :: . . :. . . . . ... . :* .: * :. : :. . . .. : . : * . *. : : :: . . . . : .: . .. . . : . . * : . : *.:. * *.*: ::: .. . . : . * * * . * * :: ..: ** .: . . .. . . : : * : *. : : .* * . .. .:.. ..* : *. * * .:.*:::. * :: . *. : .. ", "identical_positions": 76, "similar_positions": 225, "identity": "6.34%" }, { "cls_id": "homologset.agr.MGI:2444115", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K4P8-1", "uniprot_id": "HECW1_MOUSE", "id": "Q8K4P8-1", "name": "E3 ubiquitin-protein ligase HECW1", "aln": "------MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNIDIRNGAHD--AITIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIGEVSSENFLDYKNRGVNGSHRGQIIWKIDASSYFVESETKICFKYYHGVSGALRATTPSVTVKNSAAPIFKGIGSEETAQSQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSTIIGNTVNPIWQAEHFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHADDEEISLSAEPESSAETQDSIMNSMVGNSNGEPSGDATEFCKDAKPESPSEGNGVNSSENQNQEHAGPVEEAAGAMEARDGSNVSEAPEEPGELQDPEQHDTQPTLSAEEVAEGLPLDEDSPSSLLPEENTALGSK---VEEETVPENGAREEEMQKGKDEEEEEEDVSTLEQGEPGLELRVSVRKKSRPCSLPVSELETVIASACGDAETPRTHYIRIHTLLHSMPSAQRGSTTEEEDGLEEESTLKESSEKDGLSEVDTIAADPQSMEDG--ESDGATLCMAPSDCSGGHFSSLSKGIGAGQDGEAHPSTGSESDSSPQQGADHSCEGCDASCCSPSCYSTSCYSSSCYSSSCYSSSCYN----GNNRFASHTRFSSVDSAKISESTVFSSQEDEEEENSAFESVPDSVQSPELDPESTNGAGPWQDELAAPGGNAARSTEGLESPMAGPSNRREGECPILHNSQPISQLPSLRPEHHHYPTIDEPLPPNWEARIDSHGRVFYVDHINRTTTWQRPSMAPTPDGMIRSGSVHQMEQLNRRYQNIQRTMATERAEEDSGNQNSEQIPDGGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKVTLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLELPRGWEIKTDHQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLR----------------------------------------------------SYSAGEASEVSRNRGASLLARPGHSLIAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLDKLSCDADLVILLSLFEEEIMSYVPLQSAFHPGYSFSPRCSPCSSPQNSPGLQRAS------------------ARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYITFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENYLEWFRFSGRILGLALIHQYLLDAFFTRPFYKGLLKLPCDLSDLEYLDEEFHQSLQWMKDNNITD--ILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALLRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZQP0-1", "uniprot_id": "A0A8I5ZQP0_RAT", "id": "A0A8I5ZQP0-1", "name": "HECT-type E3 ubiquitin transferase", "aln": "------MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNIDIRNGAHD--GITIPRSTSDTDLVTSDSRSTLMVSSSYYSIGYSQDLVIHWDIKEEVDAGDWIGMYLIGEVSSENFLDYKNRGVNGSHRGQIIWKIDASSYFVESETKICFKYYHGVSGALRATTPSVTVKNSAAPIFKGIGSEETVQSQGNRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSTIIGNTVNPIWQAEHFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGHLQFRFEITSSIHADDEEISLNAEPES-AEVQDSVMNSVVENSSGEPPGDAAEFLKDLKPEAPSEEDGVRGSENENREHARPVEEAAGAMETRDDSKFSEGPEEVGELQDPEQHDTQPTLSAEEVAERLPLGEGCPPSLLPEESTALGSK---AEEEAIPENGAGEEEMQEKGKDEEEEEGVSALEQGEPGLELRASVRKKSRPCSLPVSELETVIASACGEAETPRTHYIRIHTLLHSMPSAQRGSTTEEEDAMEEESTLKESSEKDGLSEVDTIAADPQSMEDG--ENNGATLCMASSDCSGGHFSNLSKSIGAGQDGEAHPSTGSESDSSPQQGADHSCEGCDASCCSPSCYSTSCYSSSCYSSSCYSSSCYN----GNNRFASHTRFSSVDSAKISESTVFSSQEDEEEENSAFESVPDSVQSPELDPESTNGAGPWQDELAAPGGNAARTTEGLDSPMAGPSNRREGDCPMLHNSQPISQLPSLRPEHHHYPTIDEPLPPNWEARIDSHGRVFYVDHVNRTTTWQRPSMAPTPDGMIRSGSVHQMEQLNRRYQNIQRTIATERSEEDSGNQSCEQIPDGGAGGGG-SDSEAESSQSNLDLRREGSLSPVNSQKVTLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLELPRGWEIKTDHQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLR----------------------------------------------------SYSAGEASEVSRNRGASLLARPGHSLIAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQSAFHPGYSFSPRCSPCSSPQNSPGLQRAS------------------ARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYITFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENYLEWFRFSGRILGLALIHQYLLDAFFTRPFYKGLLKLPCDLSDLEYLDEEFHQSLQWMKDNNITD--ILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSTLYEKLLTAVEETSTFGLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q76N89-1", "uniprot_id": "HECW1_HUMAN", "id": "Q76N89-1", "name": "E3 ubiquitin-protein ligase HECW1", "aln": "------MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHD--GVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEVLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVKNSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPDDEEISLSTEPES-AQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEEAAVITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAPASTKEEPLEEEATTQSRAGREEEEK---EQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPVSELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDGLSEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLAN--GAAQDGDTHPSTGSESDSSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRFSSVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGHVERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARIDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEEDSGSQSCEQAPAGGGGGGG-SDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFITNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLR----------------------------------------------------SYSAGEASEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLARNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPRCSPCSSPQNSPGLQRAS------------------ARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITD--ILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QG29-1", "uniprot_id": "A0A8M9QG29_DANRE", "id": "A0A8M9QG29-1", "name": "HECT-type E3 ubiquitin transferase", "aln": "MNEEVMIHRQVILTQNLYQSRFLGLAAMASPSRASQGRRRCKDPIRHSFNPEQFPNVDFQNGVAEDLAAAVLRSTSDTDLLTSHCRSTLTVSTSSYTIGQTQDITLSWDIKEEVDAGDWIGMYLIDEVLSENFLDYKNRGVNGSHKGQIIWKIEASSYFVEPETKICFKYYHGVSGALRATTPCVTVKNPSAPVFKPVATDDVPQSQGRRRLISFSLSDFQATGLKKGMFFNPDPYLKIAIHPGKHSIFPALPHHGQEKRSGIVCNTINPVWQRERFNFVSLPTDVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLEKHAIGDRVVSYTLGRRLPTEHVSGQLQFRFEITSSIHPDDEDMSLSTEQPV-----------AAAEAQAQPQAEDTMSLDLGAPELPLDGDTASVEMPMDVESGQSCAAEADVIEEECLEEEQQEGEAAAAAAAMEQSETN----AEETTQVLDPINGAEE-EEAENNCAFAEE--------SSDARAGEEDEAISDPQPASEEPDADLEEDCS-LRIRTTPRRKPRPCSLPVSELETVIASACGEPETPRSHYIRIHHLLHSLPATQP--QTGDSAGPEPDRPMG-VEEEDEEEEEEGVTLEDHALTPN------GPRRTLPRSRSHERLSDLIQ----MLDGDGHP-LGAEG----QTGNQRSPDLSPVACCSHMSP----------------------------RASGPIRAQSLDSARRSESTVFSSQDDEDEMEQPNGILGSETETEQGAQCREPGDGSCQWEEAPDSHVQSPHGIVGNGEVAGPSGRRE--CPLPCNHPAVSQLPALRPDPHHYPTIDEPLPPNWEARIDSHGRVFYVDHINRTTTWQRPTSAATPDGLRRSGSVQQMEQLNRRYQTIQRTMATERREEESGSPRNDRTAN----------TETDSPLQTNELRRDTSCSPGHCQKITLLLQSPAVKFITHPEFFTVLHANYGAYRMFTNSSCLKHMVLKIRRDARNFERYQHNRDLVTFLNRFADAQLELPRGWEIKTDPQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLR----------------------------------------------------SYSAGEASEVSRTRGVSLLARPGNSLVAAIRNQSQQEPVPLAYNDKIVAFLRQPNIFEVLQERQPSFARNHSLKDKVHHIRTEGTQRLEKLSCDADLVMLLSLFEEDIMSYVPLAS-FHPGFNFSPRCSPGSSPQNSPGFLERTPLVPACCLSGESSPGTQRARAPAPYRRDFEAKLRNFYRKLEAKGYGQGPGKIKLIVRRDHLLEGTFNQVMAYSRKELQRNKLYITFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPTDLSDLEYLDEEFHQSLQWMKENDITD--VLDLTFTVNEEVFGQVTERELKSGGTNVQVTEKNKKEYIERMVKWRVERGVVQQTQALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHIVIRWFWGAVERFNNEQRLRLLQFVTGTSSVPYEGFTALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYTMLYEKLLIAVEETSTFGLE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39940-1", "uniprot_id": "RSP5_YEAST", "id": "P39940-1", "name": "E3 ubiquitin-protein ligase RSP5", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSSISVKLVAAESLY-----------------------------KRDVFRSPDPFAVLTIDG------------YQTKSTSAAKKTLNPYWN-ETFKFDDINENSILTIQVFDQKKFKKKDQGFLGVVNVRVGDVLG------------------------------------HLDEDTATSSGRPRE-------------------------------------------------------------------------------------------------------------------------------------------------------ETITRDLKKSNDGMAVSG-----------------------------------RLIVVLSKLPSSSPHSQAPSGHTASSSTNTSSTTRTNGHS---------------------------------------------------------------------------------------------------------------------------TSSTRNHSTSHPSRGTAQAVESTLQSGTTAATN-----------------------------------------------TATTSHRSTNSTSSATRQYSSFEDQYGRLPPGWERRTDNFGRTYYVDHNTRTTTWKRPTLDQT-----------EAERGNQLNANTELERRQHRGRTLPGGSS-------------------DNSSVTVQVGGGSNIPPVNG--------AAAAAFAATGGTTSGLG--------------------------------------------------ELPSGWEQRFTPEGRAYFVDHNTRTTTWVDPRR----------------QQYIR----------------------------------------------------TYGPTNTTIQQQ-------------------PVSQLGPLPSGWEMRLTNTAR------------------------VYFVDHN-----------------------------------TKTTTWDDPRLPSSLDQNVP-----------------------------QYKRDFRRKVIYFRSQPALR---ILPGQCHIKVRRKNIFEDAYQEIMRQTPEDLKKR-LMIKFDGEEGLDYGGVSREFFFLLSHEMFNPFYCLFEYSAYDNYTIQINPNSGINPEHLNYFKFIGRVVGLGVFHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDAEVYNSLNWMLENSIDG--VLDLTFSADDERFGEVVTVDLKPDGRNIEVTDGNKKEYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLVTVFDERELELLIGGIAEIDIEDWKKHTDYRG-YQESDEVIQWFWKCVSEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKAGEVQQLPKSHTCFNRVDLPQYVDYDSMKQKLTLAVEETIGFGQE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W326-1", "uniprot_id": "Q9W326_DROME", "id": "Q9W326-1", "name": "HECT-type E3 ubiquitin transferase", "aln": "------MEPPAAPVPLQPLAASSACLADRSPVDPIAVRLQQEEQAEGDDEEEEEEEEDDDDDPKEEEAFYEARNGNESDELEQAFQSALTLTN---------DVHVSVSEVEEHEP----------PLASRNQEVAEVEEQQQQLGACALPQPSEASLTGSKETREPRHHQTLLSTKSCETPANNATLSPTNSYNGSIGSDGGSSVGGGARRKSWTLSPQSGGSTPLSGAKKKTKTGAPTTTLSNANGDGFNLWVARECFETVPAEMVDTLSMAEVDEEVDEEED-EEAAAVESLLGAAAALQASAHVQRRQQQQHHQHLRQPSPPQHRPLERSWPPRAVGRDLKLQGDVFQFDILDTDERLAEEMAQG--------------------------------------------------------------------------------------------------------------------------------------SGSSNNSPLATPPVRFKPLLKKKIGPDSYINTISTQKVPVHQSYEFPTFPSSSAVGSSSSSPNSLQFPYLRQHRPLTRALSNGKASSSEEQASPRLLLSPKRPRSPPSGCSTRSASPLDISLSPE------------------QHSPTRGRGVGGALQDAVPPGTPTFHGQRPQQRLLKRVGGGAGAGATGGATG-----------------------------SPLVCPPTPTHHARRHARLQAVTANSSLASGGAIPSDPPAVSSQLDYIYLQDGGQEQGQEQSDEVVHISSTRLPSIPERSAAAAAAAAAAAAGAALMEPGTGTVSGSSGAGAAGEPPLPPAWEARMDSHGRIFYIDHTTRTTSWQRPGAAPSGGPAGREQ--HHRQQLDRRYQSIRRTITNESRAAQLYNLP-------------------TSANSNANSTAPAAPPPATAIH-------PAILMLCRPDFYSLLHTNEAALAIYNRNAALKHMVMRIRRDPPCFQRYQYNKDLVALVNTFAQMSRELPSCWETKLDQSGKQFFIDHQHRRTSFMDPRLPVECPRVVRHRQQHSQQQSSVGYYYPDLVDGNCLSATSGHINASPASSVSGVPPLPPPRPSSSSSSSRSSHGHGHNCNTTSAISCALNADRSAYGAAGMASAGATAAGYEDVPIAYNEKVIAFLRQPNILEILRERQGQHTMSRQLREKINILRVEGVPALERLGHDLQLTILLSLFEQEIMGFVPIEERSPQGSPVLNSRMPQRAP--------------------------------PPFRRDFEAKLRSFYRKLESKGYGQGPHKLKLHIRRSHLLEDAFRRIMSANKKDLQRGRLAVLWDTEEGLDYGGPSREFFFLLSRELFNPYYGLFEYSANDTYTVQVSPLSAFVDNCHDWFRFSGRVLGLALVHQYLLDAFFTRPFYKALLRLPVALSDLESLDNEFHQSLQWIRDNDIGTGVDLGLTFCVTEELLGSVVDRELKPGGKNIIINEKNKKEYLERMIKWRLERGVQEQTESLVRGFYEVIDSRLVSVFDARELELVIAGTAEIDTNDWRLNTEYRSGYHDNHQVIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGFSALRGSTGPRRFCIEKWGKPNALPRAHTCFNRLDLPPYPTPELLYEKLLLAVEETNTFGIE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :. : . . : : : ::. * . . : . : * : . : . : * * : : . .: . . . . . : . *** ** * *..** :*:** .***:*:** : . :: :: . . . . .. . : .* .* : : * *** ** : .*: :*:**: * *:::*** * :. :: . :* .:: :: * : : : * ::***. *: * : : * : :: :**.:::*.::..:* . ::*:: * : : ******.* *********:*:***:* ****** *.**:*:.* *.: : ::*:* **::**.:.*: :*****. .:** :*: *.*:* :* *.::**:*: :*.* *.*** . :* :*.*. :**..* * :.: *****:* :**: * :* :::: ** *:: . **:*** *****:*.* **** :**: :*:**. *::.. ** *** :..:.**** *****.**** :* :** *:** * *** *** *: **::******:*** * : :** ***** ** *", "identical_positions": 213, "similar_positions": 196, "identity": "12.58%" }, { "cls_id": "homologset.agr.MGI:2444120", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55034-1", "uniprot_id": "SPAG4_RAT", "id": "O55034-1", "name": "Sperm-associated antigen 4 protein", "aln": "MRRNPRPGSAASSHNHTPNFYSENSNSSHSATSGDSNGRRSAGPELGEPDGRMARGSSCGEPALSSGVPGGDTWAGSSRPKLAPRSHNGQTACGAATVRGGASEPSGSPAVLEEQLNLLPILDLRQEMPPPPVSKSFLSLFFQVLSVFLSLVADGLVCVYREICSIRFLFTAVSLLSIFLAALWWGLLYLIPPLENEPKEMLTLSQYHHRVHSQGQQLQQLQAELSKLHKEVTSVRAAHSERVAKLVFQRLNEDFVRKPDYALSSVGASIDLEKTSSDYEDRNTAYFWNRLSFWNYARPPSVILEPDVFPGNCWAFEGEQGQVVIRLPGHVQLSDITLQHPPPTVAHTGGASSAPRDFAVFGLQADDDETEVFLGKFIFEVQKSEIQTFHLQNDPPSAFPKVKIQILSNWGHPRFTCLYRVRAHGVRISESAEDNAMGVTGGPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JJF2-1", "uniprot_id": "SPAG4_MOUSE", "id": "Q9JJF2-1", "name": "Sperm-associated antigen 4 protein", "aln": "MRRSPRSGSAASSHNHTPNFYSENSNSSHSATSGDSNGRRSAGPELGEPEGRRARGSSCGEPALSPGMPGGDTWAGSSRPKLAPRSHNGQTACGAATVRGGASEPSGSSVVLEEQLNLLPILDLRQEMPTPRVSKSFLSLLFQVLSMVLSLAVDGLVCVCREICSIRFLFTAVSLLSIFLAALWWGLLYLIPPLENEPTEMLTLSQYHHRVHSQGQQLQQLQAELNKLHKEVSSVRAAHSERVAKLVFQRLNEDFVRKPDYALSSVGASIDLEKTSSDYEDQNTAYFWNRLSFWNYARPPSVILEPDVFPGNCWAFEGDKGQVVIRLPGHVQLSDITLQHPPPTVAHTGGASSAPRDFAVYGLQADD-ETEVFLGKFIFDVQKSEIQTFHLQNDPPSAFPKVKIQILSNWGHPRFTCLYRVRAHGVRTSEWADDNATGVTGGPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPE6-1", "uniprot_id": "SPAG4_HUMAN", "id": "Q9NPE6-1", "name": "Sperm-associated antigen 4 protein", "aln": "MRRSSRPGSASSSRKHTPNFFSENS--SMSITSEDSKGLRSAEPGPGEPEGRRARGPSCGEPALSAGVPGGTTWAGSSQQKPAPRSHNWQTACGAATVRGGASEPTGSPVVSEEPLDLLPTLDLRQEMPPPRVFKSFLSLLFQGLSVLLSLAGDVLVSMYREVCSIRFLFTAVSLLSLFLSAFWLGLLYLVSPLENEPKEMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSERVAKLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTVILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFGLQVYD-ETEVSLGKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRAHGVRTSEGAEGSAQ----GPH", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***..*.***:**::*****:**** * * ** **:* *** * ***:** ***.********.*:*** ******: * ****** ****************:**..* ** *:*** ********.* * ******:** **:.***. * **.: **:**************:**:*:* *****:.******.******:**.**:*************.******::****:*********************************:*** ** *:********:*********:*****.***********::*****:***:*************:* *****.********:***. * **** **** *:*:**************:****************************** ** *:..* ***", "identical_positions": 349, "similar_positions": 57, "identity": "78.6%" }, { "cls_id": "homologset.agr.MGI:2444121", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LTE0-1", "uniprot_id": "TANC2_RAT", "id": "F1LTE0-1", "name": "Protein TANC2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFRNSLKMLLTGGKSSRKNRSS--------------DGGSEEPPDRRQSSVDS-------RQSRSGPGGISTESDCAFEPDYAVPALPVSE------------------------GDVEQELGPPPSVDEAANTLMTRLG---FLLGEKVTEVQPGDQYSMEVQDENQTSAITQRISPCSTLTSSTASPPASSPCST----------------------------LPP-VSTNATAKDCSYGAVTSPTSTLESRDSGIIATLTN---YSENMERTKYVGEAGKELGSGGNLKPWQ----------------------------SQKSS-MDSCLYRVDENMAASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPN-------------------------------SVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSMSGART-QQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNASVNQGVVIVG-----------------------NIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANR---------------------ELPLTQAPSAHS--------------------SIASG----------------SCPGTPEMRRRQE------------EAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQLTAYREQLLREPHLQSMLSLRSCVQDPMASFRRGVLEPLENLHKERKIP-DEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGNFPSWLKLIVTVRTSLQEITKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNG----KMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGSIEG-TLEWEDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSQAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMAD-KQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIG----------PATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFP-REGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLKEAIKLCPNNREIQRLLMRVEEECRQMQQQQ--QPPPPPQQPPEELPEEETEP--EPQPEDIYSVQDIFEEE--YLEQDVENVSIGLQTEARPS-QGLPVIQSPPSSPAHRDSAYISSSPLGSHQVFDFR-SNSSVGSPTRQGYQSTSPALSPTHQNSHYRPSPPHTSPAHQGASYRFSPPPVGGQGKEYPSPPPSPLRRGPQYRASPPAESMSIYRSQSGSPVRYQQEANVSQLPGRPKSPLSKMA-QRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVIPTGAYGQVAHPMASKYQSSQGDMGVS--QSRLVYQGSIGGIVGDGRPVQHVQASLSAGAICQHGGLTKEDLPQRPSSAYR---GGMRYSQTPQIGRSQSASYYPVCHSKLDLERSSSQLGSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSVGLRFSPSSNSIS--STANLTPTFRPSSSIQQMEIPLKPAYDR-SCDELSPVSPTQG--------GYPSEPTRSRTTPFMGIIDKTARTQQYPHLHQ-------QNRTWAVSSVDTVLSP--TSPGNLSQPESFSPPSSISNIAFYNKTNNAQNGHLLEDDYYSPHGMLANGSRGDLLERVSQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A690-1", "uniprot_id": "TANC2_MOUSE", "id": "A2A690-1", "name": "Protein TANC2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFRNSLKMLLTGGKSSRKNRSS--------------DGGSEEPPDRRQSSVDS-------RQSRSGQGGISTESDCAFEPDYAVPPLPVSE------------------------GDVEQELGPPPSVDEAANTLMTRLG---FLLGEKVTEVQPSDQYSMEVQDENQTSAITQRISPCSTLTSSTASPPASSPCST----------------------------LPP-VSTNAAAKDCSYGAVTSPTSTLESRDSGIIATLTN---YSENMERTKYVGEGSKELGSGGNLKPWQ----------------------------SQKSS-MDSCLYRVDENMAASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPN-------------------------------SVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSLSGART-QQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNASVNQGVVIVG-----------------------NIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANR---------------------ELPLTQAPSAHS--------------------SITSG----------------SCPGTPEMRRRQE------------EAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQLTAYREQLLREPHLQSMLSLRSCVQDPMASFRRGVLEPLENLHKERKIP-DEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGNFPSWLKLIVTVRTSLQEITKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNG----KMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGSIEG-TLEWEDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMAD-KQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIG----------PATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFP-REGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLKEAIKLCPNNREIQRLLMRVEEECRQMQQQQQQQPPPPPQQPPQELPEEETEP--EPQHEDIYSVQDIFEEE--YLEQDVENVSIGLQTEARPS-QGLPVIQSPPSSPAHRDSAYISSSPLGSHQVFDFR-SNSSVGSPTRQGYQSTSPALSPTHQNSHYRPSPPHTSPAHQGASYRFSPPPVGGQSKEYPSPPPSPLRRGPQYRASPPAESMSVYRSQSGSPVRYQQETNVSQLPGRPKSPLSKMA-QRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSSAVHSSTVIPTGAYGQVAHSMASKYQSSQGDMGVS--QSRLVYQGSIGGIVGDGRPVQHVQASLSAGAICQHGGLTKEDLPQRPSSAYR---GGMRYSQTPQIGRSQSASYYPVCHSKLDLERSSSQLGSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSVGLRFSPSSNSIS--STSNLTPTFRPSSSIQQMEIPLKPAYDR-SCDELSPVSPTQG--------GYPSEPTRSRTTPFMGIIDKTARTQQYPHLHQ-------QNRTWAVSSVDTVLSP--TSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEDDYYSPHGMLANGSRGDLLERVSQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCD6-1", "uniprot_id": "TANC2_HUMAN", "id": "Q9HCD6-1", "name": "Protein TANC2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFRNSLKMLLTGGKSSRKNRSS--------------DGGSEEPPDRRQSSVDS-------RQSRSGQGGISTESDCAFEPDYAVPPLPVSE------------------------GDAEQELGPPPSVDEAANTLMTRLG---FLLGEKVTEVQPGDQYSMEVQDENQTSAITQRISPCSTLTSSTASPPASSPCST----------------------------LPP-ISTNATAKDCSYGAVTSPTSTLESRDSGIIATLTS---YSENVERTKYAGESSKELGSGGNIKPWQ----------------------------SQKSS-MDSCLYRVDENMTASTYSLNKIPERNLETVLSQSVQSIPLYLMPRPN-------------------------------SVAATSSAHLEDLAYLDEQRHTPLRTSLRMPRQSMGGART-QQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEIDAQLQSSNASVNQGVVIVG-----------------------NIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDANR---------------------ELPLTQPPSAHS--------------------SITSG----------------SCPGTPEMRRRQE------------EAMRRLASQVVAYHYCQADNAYTCLVPEFVHNVAALLCRSPQLTAYREQLLREPHLQSMLSLRSCVQDPMASFRRGVLEPLENLHKERKIP-DEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLIVTVRTSLQEITKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNG----KMDNTTFGKLSSHLKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGSIEG-TLEWEDFQQRMENLSMFLIKRRDMTRMFVHPSFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGLSKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMAD-KQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKIG----------PATWAMATSKPDIMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFP-REGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQMQQPQ--QPPPPPQ-PQQQLP-EEAEP--EPQHEDIYSVQDIFEEE--YLEQDVENVSIGLQTEARPS-QGLPVIQSPPSSPPHRDSAYISSSPLGSHQVFDFR-SSSSVGSPTRQTYQSTSPALSPTHQNSHYRPSPPHTSPAHQGGSYRFSPPPVGGQGKEYPSPPPSPLRRGPQYRASPPAESMSVYRSQSGSPVRYQQETSVSQLPGRPKSPLSKMA-QRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSPAVHSSTVIPTGAYGQVAHSMASKYQSSQGDIGVS--QSRLVYQGSIGGIVGDGRPVQHVQASLSAGAICQHGGLTKEDLPQRPSSAYR---GGVRYSQTPQIGRSQSASYYPVCHSKLDLERSSSQLGSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSVGLRFSPSSNSIS--STSNLTPTFRPSSSIQQMEIPLKPAYER-SCDELSPVSPTQG--------GYPSEPTRSRTTPFMGIIDKTARTQQYPHLHQ-------QNRTWAVSSVDTVLSP--TSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEDDYYSPHGMLANGSRGDLLERVSQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TNR7-1", "uniprot_id": "A0AB32TNR7_DANRE", "id": "A0AB32TNR7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFALTVRKACAGTRARCTWQRRKRSRPYDRTGRGPTRQNRTSSLLRQWMSHFCCASRACTSSLSLSDQSLLQSGCC----TSPRGAQGIVGDARDEVYREDIEVEDNEEGEDGDREEEQQEDQDGEEEE-SEEEKGDEGQNLGPPPSVDEAANTLMTRLG---FLLGDKVNEGPAGAQYTMEEQDDPQCLSMTQRISPCSSLASSTASPPAGSPCST----------------------------LPAGAPGNMSTRDCAYGSITSPTSTLESRDSGIIATLTS---YSENAEHGGKHSE-----GSRGSLKLWQ----------------------------AQKSMGTDSFLYRVDENMAASTYSLNKIPERSLEHSVSHSAHSIPLYLMPRPN-------------------------------SVAATSSAHLEDLAYLDEQRQAPLRTSLRMPRQNSGSSRTGQADMRVRFAPYRPPDIALKPLLFEVPSLTPDAVFTGREWLFQEVDMCLRSSESTTSQGVIIVG-----------------------NVGFGKTAIISRLVALSCHGNRMRQITSDSPHASPKHGDT------------------------LPLSQPQSAHG--------------------TLVGGS---------------SCPGTPEMRRRQE------------EALRRLAAQVVAYHYCQSDNAYTCLVPEFVHNVAALLCRAPQMQAYRDLLLRQPHLQSTLSLRACVQDPFNAFRRGLLEPLEILHRERKIACEENLIILIDGLNEAEFHKPDYGETIVSFLCKTIERFPPWLKLVVTVRTTLQDVTRPLPFHRISLDRLEESDAIDSDLQGYILHRLHASQEIQNNVALNG----KLDNTAFTKLSAHLKSLSRGSYLYLKLTLDLIEKGYLVLKSSSYKVVPVNLAEVYLLQLNMRFPTQSSFERVLPLLNVAVASLHPLTDEQAYGAVNAGMMRGASMEWEDFQQRSELLSPFLVKRRDGTRMFIHPSFREWLIWREDGEKTKFLCDPRSGHTLLAFWFSRQDSKLNRQQTLELGHHILKAHIFKGLSKKVGVSSSVLQGLWVSYSTEGLSTALASLRNLYTPNVKVSRLLIMGGANVNYRTEVLNNAPILCVHAHLGYLETAALLLEFGADVDGVSESGLTPLGYAAAAGHLSIVTALCSKKAKVDHLDKNGQCALVHAALRGHLEVVKYLVQCEWNTDGQQVGSFSKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEEEERAQINNFDTLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGIVPLFSAVRQGHWQIVDLLLNHGADVNMAD-KQGRTPLMMAASEGHLGTAEFLLAQGASLSLMDKEGLTALSWACLKGHLPLVRALVERGAATAHADKSGRTPLDLAAFYGDSEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVALLKKGAKIGCQTLPTRARGPATWAMATSKPDIMIVLLSKLIEEGDGFYKKGKVKEAAQRYQYALKKFP-REGFTEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFASKALELKPKSYEAYYARARAKRSSRQFHAALEDLSEAVRLCPNNREIQRLLQRVEEECRQVEQQQ--ELDPPPSPPREQAPSMVPPPPMEPHISDMEPVQDLFEEDDDYLERDLDGLPLGVAAETHIIPSGLPVIQNMPPSPSHHESPYLG-------QTYDLRPSPPSMSSPTRQGYQSTSPSLSPTHQSSHFRPSPPHQ------ASYHFSPP-------------PSPLRRGPQYRSSPTSEAAAMYRPQSASAGRYQQDP----LAGRPKSPLSKMSSQRSFQFSQQPSQPAQQSQWLQPAKAQIVRTNQPSTAVHSSAVLGSSAYSQIAHSMSARCPGDMDELGDGGYSSSLQPQGSLS------------AGALYQRAISMDPGLMEDELPQRPSSAYRPTPGGVRYGQTPQISRSQSTAYYPVPPHEMERQVT---LGSPENLHAHRRPVSANSAEPKQHPPGPRPLIHSHSTGLRFSPSTNSLGPASAANLGPGFRASTSAQQMEIPLKLSYESGYHDDLSPVSPPQGTDFRVVGGTYPGEALRSRNTPFMGIIDKTARTRQYLPQQPSLVSSSSSSRPWTVSSLDTVVNSPATSPSNVGYGQQTAP---LSHIAYYNRTNNAHNGHLMDEDFYANPPGVTR-DRADAMGRVSQVPTYPDVKMARTLPVSQAYQDNEFRQMSRSERQGPTSPIKPKRPFVESNV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTS9-1", "uniprot_id": "Q9VTS9_DROME", "id": "Q9VTS9-1", "name": "", "aln": "MPSLQQIALAMEGDQSELQTPPLPINPPPKVMANGIVYGFRTRHLSCIEENDSDSLHGSSIPHAYDMMQQADETFQKLNANEEQDESGSEDGGLENLDDTIAMIDESRLLEADYLDELVAEEQLQEQDEDEEESSDLVDSGNVEEDFWQPSFNRNDIMMTSVYGALNGSLTSEVSSTAAPGYSECATPRKEAEPVYATPEKRRASNRSFDSTCASLTSSLYGGSMNSSLDLKYSSLGGGDSVSGGISGTSTLRGTSVPPMDLSMISSDGVSALDWGSASVSCVLDSGDGNPAEELNEEMAAKCLSAAESDLQSIRRLLEHDASGSVCPSCRISFDKGKRRKLIDTCGHERCYSCMFRNDQCPMCMNSSLKDVDGANAQGYDTGIGGSTSTIVSPLGSPQPQLRSHAQRNAALARYMQQHRQESQSPDYHHRYASNGKLPRAAALSTNGNGFTTGTTQTVTVDVHHQLGGGGGGAAAAAKQLMANGISGHSRSSSMSHNIHAAAYSELSAAPPAFATPPTRRRFFNHKNLRSALTGGSGGGSGVGGGVGGAGGVGGGHRRTASNGGCPIDTASILSGDHTHQHHHRDNQPEGKESNALNTSTCSDSAVTRRRRKNVSNHNLKTSARHGASSENRLNRLSLAGTSVYAGHLSSLVFGKIKSLWSVNSSNSSEAGLNQLAGSDAIDHHSSFLNEKLQKDQLHARLGLLLNDPGSNGNSSSSGSGCEPISAHSTTSTTSSSGVGAASTTTSGSSQNVSPEQTLASGAGMLSGSQLSVATSHGVKEDALSLCGKFKAGCSMLHVYEALPSKSRKGNVRRSTRGQQGSSSSASAASAVGSRVTASSLAAVQLALKPLFFEVPLQEPDPPYVGRQWLVQQLSNILLGTETRVVLINGQPGTGKTAFCLQLVEYSCFGRRQMQDDPDGIYSQLQLGAHCERMRGLASHMVGYHFCQADANLTCQVPDFVHSLAAQLCQAPQLTAYRDYLLSEPHLQDILSVRECIADAERVMKLAILEPLAHLHRAGKIP-AKVAVIVVDALCEAEYHRPDHGHTIASFLAQLTPHFPAWLKLVATVRTQMLELVKAPSYTQLTLDSWASSQALQQDMLDYIGARLADSPEIRMNIGGGGGQNSQSGSQPQTKFVSHLQSLSRGSMLYAKLILDLIARGQLVIKSSSYKVLPVSLAQIFLLHFNLRFPTARSFEQAAPILNICLAALYPLTLDEIYYSMEALSHGREALSWPDFMQRFKLLDGFLIKRLDNTYMFFHSSLREWLMRRDEGESNKFLCDARLGHAGIAFRLSRLQAPLSPQLTLELGHHMLKAHLYGGTSLTL-LSPRDLQSYWLAGAADNISSSLGALRNVYSPNLKVSRLVLLAGASPNHRTDYMGGAPILCIAAHEGILPMVSLLLEFGADVGLTNSQGCTPLILAAMRGHCDVVRPLVAAGSSLGQLDITQRCALVHAARMGHLSVVKYLLACDWSPRPHSQDVTR-SVALQQALIGAAAQAHCKILEDLLDLNETEFD----LDVNGMEPSSGELALTAAARHGCIDVVGILLSRGAQIDARNRQGYSALWLAVKEGHWSVVEHLLQRGALLDEPLGQTRKTPLMIAAEEGHLELVDLLLARGAQREAQDHEGFTALSWACLRGHLAAAKTLIEHGCNRHHEDHNGRTALDLAAYQGAASLVIYILEQGGNLEHIDVHGMRPLDRAIACRNIQAVQVFLRKGAKLG----------PTTWSMAMGKPEILVILLNKLLEDGNVLYRKNRFQEAAHRYQYALRKISGLEQLLERNAIFAQLRTNLLLNLSRCKRKLNELDASIDLATQAIAQKPHSYEGYYARAKARMELGALNEALVDANEAMQQAAQSG----VLCEVVEVLKRIQTEL---------------------------------------------------------------------------------------------------LTRISISSEDQTGRMSNIGGGASVAYESHHEITDL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. .: . :: ... . * :* :.. * : : . * : * ..:. ::.*::: ** * .:. . . :* : ::: * :* :. ..*. ::* .. .. :* :. . : : . ::. ::. * *.: ..: :. * :..: : . * *.: *: :. : .: : :** * . :..* : .:. :: . : . * . : :*.* *::** * : . . :: ::. . : . ... . :*: . .: *..: .* . . *.: : .*. ::. : * . : . * : * :*. *. .:. :*. : :** :. ..: : .* ** * :*: : * :* **:::*.**:**:* ** **:***.:** **::**: ***: ** :****. **:* *: *. :: .:**** **: **. : :*::*.* ***:*:**:*.**.***.: .**.****:.**** : ::.: .: :: ** ..:*::.*: ** *: * **: *:. .* : .. . *: :**::**:** ** ** :*** :* **:*******:**.*::::**: *::*** **::. *:**:.:*:*:*** :. : :::* ::.* ** ** : *. **:** * * **.*.*:****: *::**..*****.* **: :** :** :. *. * *:*****:****:: * * .: :*. **. *:: :::.:* :*.:***:*:**:*****:::.**. *:**: :..*****: :* * .:*******:*. ...* *** ** *. .:* * :.:.:** . :******* ***.***:*: *:*. :. . * *:*****.**: .: :*:. **** *.: : ::*.::. ** ****** :* ::* :**.:** : **:* .*: :*::***.:*: ** :** :: . : :****:**.**** .::***:**. *:**:********:***. .::*::.*. * *:.***.*****: * :.:* :::::*. :**:* ********:.*** ..* .:*:****:* *:**:** .**:*:::**.**:*:*: :*:*.:.:***:******:*:. * : * * :*:..********:**:*::. : ::*::*: **:***.*****:*: . : ** * .**:: ..:. :* .* * :::: : *:.* : *. . :.. .**.. : ", "identical_positions": 464, "similar_positions": 493, "identity": "18.32%" }, { "cls_id": "homologset.agr.MGI:2444128", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C2K5-1", "uniprot_id": "RASL3_MOUSE", "id": "Q8C2K5-1", "name": "RAS protein activator like-3", "aln": "--MKPECGQTMFRTFWSRSRDSSAMDPPLQSEEDSQTQPSLPSPLTSYRWHTGGSGEKAAG----------GFRWGRFAGWGRALSHQEPMVNSQP---------------APRSLFRRVLSAPPKESRSNRLRFSKTLWGR------------------HKNVAPLEPKPNPKAPEPELELVADPDLPVAQIPEPPTPDMPVWNIDGFTLLEGKLVMLG--EEEGPRQIRVGSASSENSMQAALGNLKDAVRTPGKTEPEAAGSNQVHNVRKLLKR-LKEKKRAKSELGAYTPRDGPPSALGSR--ESLAT----LSELDLGAERDVRVWPLHPSLLGEPYCFQVTW-AGGSLCFSCRSSAERDRWIEDLRRQFQPSQDNVERQEMWLTVWVHEAKGLPRATV--PGVRAELWLDGALLARTAPRAG-------------------------PGQLFWAERFHFEALPPARRLSLRLR-SAGPAGATVGR---VVLELDEVSIPRAPAAG----LERWFPVLGAPAG--------------------AVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCGALEPALSAQAKEE-----LAAAMVRVLRATGRAQALVTDLGTAELARCGGREALLFR--------------ENTLATKAIDEYMKLVAQEYLQDTLGQVVRCLCASTEDCEVDPSKCPTP-------ELPKHQARLRDSCEEVFENIIHSYNCFPAELGSVFSSWREACKARGSEA---LGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMAFMNSFLEDHGPAMQHFLDQVATVDADTTPS---GYQGSGDLALQLAVLHVQLCTIFAELDQKTQDSLEPLPTILRAIEEGRPVPVSVPMR-------------------------------------LPRISTQVQSSFFSGEKPGFLAP--------------------------------------------------------------------------------------------------------------------------------------------------------RDLPKHTPLISKSQSLRSFQGAG--SWASRRPDEERP-----------------------QRRPRPVLRTQSVPARRPTHRRPSAGSKPRPKG-----------------------------------------------SLRMGPAPCGRAWTRASASLPRKPSVPWQRQMDQPGDRYQTTGTHRPVGKLAEIQCEVAIFR------EAQKALSLLVESLSTQVQALKEQQEHFRCQLQDLYSRLGAGISKLDSKGGLPSNGSHRLKSLEQRLTEM--------ECSQDQLRDSLQSLQLLSKTPG-SRSQPLPLKAPCVNGADLSMGT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZWW3-1", "uniprot_id": "D3ZWW3_RAT", "id": "D3ZWW3-1", "name": "", "aln": "------------------------MDPPLQNE-DSQTQ---PSPLTSYRWHTGGRGEKIAG----------GFRWGRFAGWGRALSHQEPMVSSQP---------------APRSLFRRVLSAPPKESRPNRLRFSKSLWGR------------------HKNVVPLEPKLNPKAPEPELELEGAPDLRAAHIPEPPAPDMPVWNIDGFALLEGRLVMLG--EEEGPRQIRMGSASSESSMQAALGNLKDPVRTPGKIEPEATGSNQVHNVRKLLKR-LKEKKRAKSELGAHTPRDGPSSALGSR--ESLAT----LSELDLGVERDVRVWPLHPSLLGEPYCFQVTW-AGGSRCFSCRSSAERDRWIEDLRRQFQPSQDNVERQETWLTVWVHEAKGLPRAAA--PGVRAELWLDGALLARTAPRAG-------------------------PDQLFWAERFHFEALPPARRLSLRLR-GAGPAGATVGR---VVLELDEVSIPRAPAAG----LERWFPVLGAPAG--------------------AVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCMALEPALSAQAKEE-----LAAAMVRVLRATGRAQALVTDLGTAELERCGGREALLFR--------------ENTLATKAIDEYMKLVAQEYLQETLGQVVRSLCASTEDCEVDPSKCPTP-------ELPKCQARLRSSCEEVFENIIHSYNYFPAELGTVFSNWREACKARGSEA---LGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMVFMNSFLEDHGPAMRHFLDQVAMVDTDTTPS---GYQGSGDLALQLAVLHVQLCTIFAELDQKTRDSLEPLPTILQAIEEGRPVPVSVPMR-------------------------------------LPLNTAHVQSSFSSGEKPGFLAP--------------------------------------------------------------------------------------------------------------------------------------------------------RDLPKHTPLISKSQSLRSFQGAG--SWARRRPDGERP-----------------------QRRPRPVLRTQSVPARRPTHHRPAAGSKPRPKG-----------------------------------------------SLRTGPATSGRAWARTSTSLPRKPSVPWQRQLDQPGDRYQTPGTHRPVGKLAEIQCEVAALR------EEQKALSHLVESLSTHIQALTEQQEQLRCQLQDLDSRLGAGISKLDSKGGLPSNGSLGLKSLEHRMTEM--------ECSQNQLRDTLQSLQLLSKTPG-SRSQPPPLKAPCVNGADLSMGT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86YV0-1", "uniprot_id": "RASL3_HUMAN", "id": "Q86YV0-1", "name": "RAS protein activator like-3", "aln": "------------------------MDPPSPSR-TSQTQPTATSPLTSYRWHTGGGGEKAAG----------GFRWGRFAGWGRALSHQEPMVSTQP---------------APRSIFRRVLSAPPKESRTSRLRLSKALWGR------------------HKNPPP-EPDPEPEQEAPELEPEPELEPPTPQIPEAPTPNVPVWDIGGFTLLDGKLVLLGG-EEEGPRRPRVGSASSEGSIHVAMGNFRDPDRMPGKTEPETAGPNQVHNVRGLLKR-LKEKKKARLE-----PRDGPPSALGSR--ESLAT----LSELDLGAERDVRIWPLHPSLLGEPHCFQVTW-TGGSRCFSCRSAAERDRWIEDLRRQFQPTQDNVEREETWLSVWVHEAKGLPRAAAGAPGVRAELWLDGALLARTAPRAG-------------------------PGQLFWAERFHFEALPPARRLSLRLR-GLGPGSAVLGR---VALALEELDAPRAPAAG----LERWFPLLGAPAG--------------------AALRARIRARRLRVLPSERYKELAEFLTFHYARLCGALEPALPAQAKEE-----LAAAMVRVLRATGRAQALVTDLGTAELARCGGREALLFR--------------ENTLATKAIDEYMKLVAQDYLQETLGQVVRRLCASTEDCEVDPSKCPAS-------ELPEHQARLRNSCEEVFETIIHSYDWFPAELGIVFSSWREACKERGSEV---LGPRLVCASLFLRLLCPAILAPSLFGLAPDHPAPGPARTLTLIAKVIQNLANRAPFGEKEAYMGFMNSFLEEHGPAMQCFLDQVAMVDVDAAPS---GYQGSGDLALQLAVLHAQLCTIFAELDQTTRDTLEPLPTILRAIEEGQPVLVSVPMR-------------------------------------LPLPPAQVHSSLSAGEKPGFLAP--------------------------------------------------------------------------------------------------------------------------------------------------------RDLPKHTPLISKSQSLRSVRRSE--SWARPRPDEERP-----------------------LRRPRPVQRTQSVPVRRPARRRQSAGPWPRPKG-----------------------------------------------SLSMGPAPRARPWTRDSASLPRKPSVPWQRQMDQPQDRNQALGTHRPVNKLAELQCEVAALR------EEQKVLSRLVESLSTQIRALTEQQEQLRGQLQDLDSRLRAGSSEFDSEHNLTSNEGHSLKNLEHRLNEM--------ERTQAQLRDAVQSLQLSPRTRG-SWSQPQPLKAPCLNGDTT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDZ7-1", "uniprot_id": "E7FDZ7_DANRE", "id": "E7FDZ7-1", "name": "", "aln": "MGTNKESNAEQAGAASQIEEDMELVPEQNSPVDQDPRQTEDGKLLNTYKWHTGAKAETVAQGAIERLEKGASNKWNKMQSWRKALSEDPGEKSSTANRGGESPSKPDKPTTSRKNPFRRALSEPPGSLLASSAPASSSAQATGSTVQDTTQRGKIRKYLQTVSQRFKKPRLQSTVTEHEKCEPDYVLQDPVRLSWAPPQEVPVWDISNCFLQDGQILIPREEEPMMTVRNRASSCLFSVSLQNISGSHAELNPDPVVPSSGTKLKGQDGGVKGLIKRRLQGDDKRKSSTQLNTAGLSVAARYGSK--ESLSIPVSAAKSLNLSADQTTVIRPVHSSILGEKYCFQVIN-SENNHCFGCTSAAERDRWIEDLRRTAHPNKDNCERTENSLCLWINEAKDLPPKKR----YYCEVHLDGTLFARTSSRAVGKSVQRSSQAVDGGSGAFGSGGTSGGCQLFWGEFFELDNLPPVTQITLHLFKGEDPKKKRHSRDDATLHPLGSVALPLADIKGRAY-QEKWYRIVAYKPPGTS--------TAKDSVELQASIRVKAKFKNLKILPIERYKEFAEYVTVNYVDMCSSLEPLLNVREKEE-----LAGALVHVLQSIGKAKEFLIDLGSAEVQRLGENEALIFR--------------ENTLATKAIDEYMKLVGQKYLIDTLGDFIARLYNGGENCEVDPLKCSPS-------DLPINQRHLKETCEDVVKRITDMQESFPAELNDIFSSWVSDCEDRGQQD---IGQRLISASLFLRFLCPAILSPSLFGLTQPYPETNTLRTLTLTAKVIQNLANFTLFGEKEEYMFFMNDFLTQHWEPMRDFLQKVSNPESEITMS---RFDGYVDLPLRLAVLHNLLVDIISVMKQDQIDNLHPLPRILNQIT---EFLGHDAQQ-------------------------------------IPVSSNQAMP------KPIYVPP--------------------------------------------------------------------------------------------------------------------------------------------------------RDLPKYSPLQTSMQQLPIDSKPNQCTKERQRRQVQRA-----------------------FSVPNRPSRQQRQPMKRQASNEELPTQCPDDNQ-----------------------------------------------DHRLEISPPSNPEKSKAAAAAK---VHWIKQPDGSETCQVRRQDREETNTLDKHAQELSELR------MGVEQVTERELEMAKRLEDFIVLTQDQNAQLQAEVQDLRN---LLAIREEQLASATFRLGVIEEEREED--------ERKLNVAVAAVERMNVLEEQFAGLLKDVHHLYAANSDGLRQTYINT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T498-1", "uniprot_id": "GAP2_DROME", "id": "Q8T498-1", "name": "Ras GTPase-activating protein raskol", "aln": "--------------------------MGRRTYLSRSSTISYPSRIEGWLDVCETEG--ELT------------RLIKTLPWGPLYCVLQQDDQTFTAYCS-----------EEISLGDVCYEDIPRVRLDRVRRPAKALWDG-------------------------PPTLVEENEDSDSCVGG--SGGMSGINDIVLNTTLYSELGEYKSKTLPRIHFDT-------ALNDTSLNEDTSYEKACRRGSAPTTPILGSKQHQTEHNATSRFTNFFSKKSNPLKRTKSVTKLERTKRGSGGLRGSRSHESLLSSHAVMSTIDLSCTGAVGVAPVHQSVLGRRHCFQVRGGPRGERYYSCGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKR----YFCELQLDKTLYGRTSVKLQ-------------------------TDLLFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKY-----QFVGSVKIPVHDVTSRLP-CEQWYPILSDKAGDSLGRTSGGGGSGSKDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKED-----IGQALVLLMHAQGLAGAFLTDVVALDLLRVGD-QRLTFR--------------GNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSS----AGSLQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGRQD---MADNLISASIFLRFLCPAILSPSLFNITSELPSARATRNLTLVAKTLQTLANFTRFQGKENFMEFLNDFLEQEAARMQQFLEIISTRPEHPAPDSILDWAGYIDQGKQLSILHSLLSESLAKLPEARQHELDPLQHILDEISRAKEHGMGTALPGGYLPATSSTHSIASENQENRNPGSSGSHAGSNSEQLLPQQSQLAQPQHAIVSKPLSAERGIMRGVLTPNSLEKNIFRYNDPTVNGLLQQQQQQQQQQQQQQQQHQQLQQHGHQQQPHHQHPLQMLSNSQTSIAGNQYMSSPGGLQHAQSQTSMASSSLNGSSSNLLHGHQQHAHHPQQLHPHHCPPAPQTSASSTMERMDRMNYPYMSHNGNDYETSTPSSTRSRTLPRNGNPNANGNVGSSNNNQSGSYDDMHGEFQIQISGFDTSSAFVCKSPTPMMKSSLGPAGAGRSHHKLNLGIPDHSGGYVRGNNLNPNSNMPKNLEDLDDLFKYAEEHDVAEPANHHNHNQGQQNHQGHLKPAAVPGKEQLSAKSSHCSSGYQSISTNPSPSQSSSPVESQLKAAMGSHNAPLAFKNPSYQLQPQTGSSRSSAQSNTHQQQQQQQQQQFGSRLKPIGGGLVAARAAFLNSGGALEAATLTPSSSDEQLSADNYFSYAAAAAAGAGIATKLEAQRSLSGGSSSSTSASASTSNLGKSGGSSAYGRLNGPLKREDVYGSGYGGSSGNVGYGLSTSSAAGHHQHPHQQQQNPMQQQQQRERDQEHKQYAGSVAGSVGSATSAAQRRLSLDSARTLSDSSTDTEGHCNQLQEGKRRRQLRSSGGSGGGGAGSEQGLGKSYDQNGEIQLLQQTLDTLCHTLDRDEAELRDSSDELFGLQRPAGSNGSNNLSLQSESTMRSIIDRLITMEEELRREQLKMSLALSHKQRVIEEQGQQIAALDAANSRLLSALTALRQRYETQQQQQQHQAPPKTQKPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33314-1", "uniprot_id": "BUD2_YEAST", "id": "P33314-1", "name": "Inhibitory regulator protein BUD2/CLA2", "aln": "---------------------MSSNNEPAQSRTSYFKLNEFLSNVKHYKNTFKGEIQWCNNLSLN----DWKTHYLQITSTGALTHSIDELTADSTNIQP---------IIKHLQQCRIEIIKDKHSSFKDINANCNFIIQVN--------------TSGKDNKVYLRVKSWSDFKKLLTCLIWWSSMKTNGIFNKFQVSRPLEFKSKKMAKPESLLVYKLNVFGPIVKNIVLPPATNILESPDIINNDDNSVGWFSAMGVLKSNGMLDLLLQSDGSLIYSLNISQLLRSEIRILDSSVLQSENSLFLGELPLLRSQLGLEKFRIENIASAATNSSDISQEIIVEFPLRIDLEDCFIALQSFARSEYLSITGSDKSNDMKISNSFKISILEANFQSINLNDKNNTPWSIFTDITAWGHTWARTSMVSN-------------------------SSNPFWREEFQFNELLRLTNSYLEIKQLFHDLNNKKRLR-----LIGKIKITQEIINDTRYNKETRLPIMDVDNKN----------------FQIGTICIKISSNLNFILPSTNFVKLEKLLMNANLSMVSNLIYKSSSSMENDNKLTQTSIIFLDIFQSLSRIEEWFHVLIDKELAKIDGTVSRINQKNLDSKHVFNSLFRGNSILTKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYKRLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNGISGLLFLRFFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFANKEPWLMKMNNFIDKRHNDLLDYIDKMTQKK--------------LDFNSKILNLSSTISRPKLAIEQTMLDDLPQIPYLLDKNLRETEFVNLIVNFSQ-----------------------------------EDMTKMEKYNHMDNGGKGELIEE--------------------------------------------------------------------------------------------------------------------------------------------------------EGLLSGSSLNLSVDKKDLDSPIEVKPEIGELEFEKIT------------------------ENNTEIFGDDLMNLLKSDDVGSRSRDLDNGANSG---------------------------------------------IKFNSIIPKAEEEKHAMKELEQESCLLYNRINHIRKRLSGYECASSTLFEDKKYSISLSHKIFYEEIKEGKEIVLKLLNKPTNENSSARLQKFFTKGVSSKSNNTVGDSYCKFLTIDVSDENPKSSNKTSVHGTSSEN------GAKDDYLTLPNSQGKGNLGNRFSPTKLSRIMRKPPNADVPKEQNSRKLTRWFKKKKETGGS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : . . .. : . : . . . . . : . . . :: . : * :.. .:. . : . . *. :: . . . : :: .* :: .**: ** * *.: : :.: : .: . . * :: : : . :** : :: : : * ::: . :: :::: . . : :: : . : *:: **::: :: ..:.** .:*. : : . ..**:** : : * : : . :* :: : : . : : : . :.. :***::**.** *.** . . *.*** :*.: .*:. : * ** :: :*.*: .. : ::: :: * :: * : : : . * : :* * .. . :. : . . . : . .. . : : . : . . ", "identical_positions": 51, "similar_positions": 183, "identity": "2.95%" }, { "cls_id": "homologset.agr.MGI:2444129", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A068-1", "uniprot_id": "D4A068_RAT", "id": "D4A068-1", "name": "", "aln": "MAVALLEEWCKIMGVDVQKSLLVIGIPVNCGELEVQTVLQEALKCVGSYRLLGKILQKQDNTSAVLLELMEDTDMSVVPSEVQGKGGVWKVIFKTPNQDTEFLQRLNLFLEKEGQTVAGMFRALKHEGVSPATTPCTSPELLAHLVGQAMVHAQRPLLPVRYCKLRVFSGSTVAAPEEEPFEVWLEQATEIAKEWPIPETEKKRWVTESLRGPALDLMHIVQADNPSISAEECLEAFKQVFGSMESRRTSQVKYLKTYQQEGEKISAYVLRLETLLRRAVEKRAIPRNIADQVRLEQVMAGANLSNVLWCRLRELKDQGPLPTFLQLMKVVREEEEEE-AYFEHESREEPGEREGSGRWDNSRNN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHK0-1", "uniprot_id": "PNMA2_MOUSE", "id": "Q8BHK0-1", "name": "Paraneoplastic antigen Ma2 homolog", "aln": "MAVALLEEWCKIMGVDVQKSLLVVDIPVDCGEPEIQTVLQEALKCVGSYRLLGKIFQKQDNTSVVLVELMEDTDMSVVPSEVQGKGGVWKVIFKTPNQDTEFLQRLNLFLEKEGQTVAGMFRALKHEGVSPATPPCTSPELLAHLTGQAMVHGQRPLLPVKYCKMRIFSGSTAAAPEEEPFEVWLEQATEIAKEWPIPEAEKKRWVAESLRGPALDLMHIVQADNPSISVGECLEAFKQVFGSTESRRTSQVKYLRTYQQEGEKISAYVLRLETLLRRAVEKRAIPRNIADQVRLEQVMAGANLGNVLWCRLQELKDQGPLPTFLQLMKVIREEEEEEDAYFEQESREEPGEREGSGCWNNSRNN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UL42-1", "uniprot_id": "PNMA2_HUMAN", "id": "Q9UL42-1", "name": "Paraneoplastic antigen Ma2", "aln": "MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQEVLQETLKSLGRYRLLGKIFRKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGMFRALGQEGVSPATVPCISPELLAHLLGQAMAHAPQPLLPMRYRKLRVFSGSAVPAPEEESFEVWLEQATEIVKEWPVTEAEKKRWLAESLRGPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRRIADQVRLEQVMAGATLNQMLWCRLRELKDQGPPPSFLELMKVIREEEEEE-ASFENESIEEPEERDGYGRWNHEGDD", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:****:**:**.** ****:* .**.: * *:* ****:**.:* *******::**:*:..**:**:****:*.:*************************:*************:****** :******* ** ******** ****.*. :****::* *:*:****:..*****.***********.****:.*:*****::**********************. ************ *****:**:**:***:****:**********************.**************.*.::*****:******* *:**:****:******* * **:** *** **:* * *::. ::", "identical_positions": 277, "similar_positions": 65, "identity": "75.89%" }, { "cls_id": "homologset.agr.MGI:2444131", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4R9-1", "uniprot_id": "D4A4R9_RAT", "id": "D4A4R9-1", "name": "PGAP2-interacting protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSLWRAIALETLLGYISWSLYHGLGPMIYYFPLQTLELTGLEVFGVAFLSPILLTIPPFWKLVKKKRALTLLRIITVGSVASFEAPNAKLRLIVLALGVSSSLIVQTVTWWSGSGLQRYLKIWGFILGHILLLVLRIWYTSLNPIWSYQMSNRVILSLSAIAVFDRISTDGDYRNPEGKK-PDEAATRRTSLSSWLLPGAAFGSLVFLTHWIFGEVSIVSRWAVSGHPHP-GPDPNPFGGAVLLGFASGLMLSGSSWLCDTGLAWWMTGATSAMGLLYLRTWAAAVSGCALAVFTGSMWPQVLGHLMNSGTNPGGAMTTGMSLYVLQVFFCAWCTAFKFVPGGVYARERSDVLLGIIMVIIGLSMLFRPKKNLDFLLQTKNSSKMLLRSTEKYMKLILWLLVGVGLLGLGLRHRTYERKLGHGAPADVVSAAIWPFRFGYDNEGWSNLERSAQLLKQTGADFITILESDASKPYMGNNDLTMWLGEKLGFYTDFGPSTRDHTWGIMVLSRYPIVRSEHHLLPSPEGEIAPAITMTVNIS-DRLVDFVVTHFGNHEDDLDRKLQAIAVSKLLKNCSNQVIFLGYITSEPGSRDY-TQLTKHGHVKDIDSSDRDRWCEYIMYRGLIRLGYARISHAELSDSEIQMAKFRIPDDPFNYRDNQRVVIDHRGVPKNIHFNPRFGSYKEGHNHENNHHFHMNTPKYFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YL7-1", "uniprot_id": "PG2IP_MOUSE", "id": "Q91YL7-1", "name": "PGAP2-interacting protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGLWRAIALETLLGYVSWSLYHGLSPMIYYFPLQTLELTGLEFFCVAFLSPILLTIPPLWKLVNKKWTLSLLRIVTVGSIASFEAPNAKLRLMVLALGVSSSLIVQTVTWWSGSGLQRYLKIWGFILGHVLLLVLRIWYTSLNPIWSYQMSNRVILTLSAVAVLDRIGTDGDYRNPEGKK-PREVATGRTSLSSWLLPGAAFGSLLFLTHWIFGEVSIVSRWAVSGHPHP-GPDPNPFGGAVLLGFSSGLMLSGSSWLHDAGLAWWMTGAASAMGLLYLRTWAAAVSGCVLAVFTGSMWPQVLGHLVNSGKNSGEAMATGMILYVLQTFFCAWCTAFKFVPGGVYARERSDVLLGTIMVIIGLSMLFGPKKNLDFLLQTKNSPKTLLRCSEKYMKLILWLFVGVGLLGLGLRHRTYERQLGRGAPATVVSAAIWPFRFGYDNEGWPNLERSAQLLKETGADFITILESDASKPYIGNNDLTMWLGEKLGFYTDFGPSTRDHTWGIMVLSRYPIVRSEHHLLPSPEGEIAPAITMTVNVS-NRLVDFVVTHFGNHEDDLDRKLQAIAVSKLLKNCSNQVIFLGYITSEPGSRDY-IQLTKHGNVKDIDSSDGDRWCEYIMYRGLIRLGYARISHAELSDSEIQMAKFRIPDDPANYRDNQKVVIDHRGVPKNIHFNPRFGSYKEGHNYENTHHFHMNTPKYFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H720-1", "uniprot_id": "PG2IP_HUMAN", "id": "Q9H720-1", "name": "PGAP2-interacting protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSLWREILLESLLGCVSWSLYHDLGPMIYYFPLQTLELTGLEGFSIAFLSPIFLTITPFWKLVNKKWMLTLLRIITIGSIASFQAPNAKLRLMVLALGVSSSLIVQAVTWWSGSHLQRYLRIWGFILGQIVLVVLRIWYTSLNPIWSYQMSNKVILTLSAIATLDRIGTDGDCSKPEEKK-TGEVATGMASRPNWLLAGAAFGSLVFLTHWVFGEVSLVSRWAVSGHPHP-GPDPNPFGGAVLLCLASGLMLPSCLWFRGTGLIWWVTGTASAAGLLYLHTWAAAVSGCVFAIFTASMWPQTLGHLINSGTNPGKTMTIAMIFYLLEIFFCAWCTAFKFVPGGVYARERSDVLLGTMMLIIGLNMLFGPKKNLDLLLQTKNSSKVLFRKSEKYMKLFLWLLVGVGLLGLGLRHKAYERKLGKVAPTKEVSAAIWPFRFGYDNEGWSSLERSAHLLNETGADFITILESDASKPYMGNNDLTMWLGEKLGFYTDFGPSTRYHTWGIMALSRYPIVKSEHHLLPSPEGEIAPAITLTVNIS-GKLVDFVVTHFGNHEDDLDRKLQAIAVSKLLKSSSNQVIFLGYITSAPGSRDY-LQLTEHGNVKDIDSTDHDRWCEYIMYRGLIRLGYARISHAELSDSEIQMAKFRIPDDPTNYRDNQKVVIDHREVSEKIHFNPRFGSYKEGHNYENNHHFHMNTPKYFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P25618-1", "uniprot_id": "CWH43_YEAST", "id": "P25618-1", "name": "Protein CWH43", "aln": "MLIINGKIIPIAHTICAFSAFFAALVTGYSLHFHKIVTNAHYTYPDEWFPSVSATIGDRYPERSIFQILIALTAFPRFLLLLGHYYLNQSKVCFLVGVLRTVSCGGWVYITSTDDHDIHDIFMITYIVLTLPWDIMITRYSSPLTSKNKGLTATIFFGTLFPMIYWYIQHSVQQRAGAYSIYAYFEWSLILLDIAFDAFAYADFKKIDIVLAFNEKPGNTSFFQIRDSSPINYGEEKSSELQKSGEKKVEKEKPVARSATGSYFRFDSFFYLLTNIFNGFLFWSNVTSLLCSIWHFPLWYMGISGYEAAILGYLGPIFLYLP-FVSEAFTQYGVLLGGIIAIG-AYIVQMPELRLISVAVGTSITVATFVQNLRYITNAETS-FSFALTWLLGLVASVILKMGFYTNNPTWVILDERNGGYNKTALVLTVLFGMLSPYVNSINFEGKRNAQAKSASLIGKLFLAVGFGSLLFGIHQLLTDSSTTIYWAWEGYNESHGPLPWPWGALTCTVMLFASLSSVKFMGKPLVPCLLLLISTAVLSARSITQWPKYIFGGLLYAIAMLWLVPSYFSALGQVQN-IWVYVLSFSVYIIFVLAHVWVVAYAFVPMGWVLREKIETVLAFSSTFIIIGALTCKNLNIQLVTMGKKFFIYVFFFAVALLSLTARFVYDIRPTGIPQPYHPDS---------QLITAGIWTIHFGLDNDMWASEDRMINLIKDMELDVVGLLETDTQRITMGNRDLTSKLAHDLNMYADFGPGPNKHTWGCVLLSKFPIVNSTHHLLPSPVGELAPAIHATLQTYNDTLVDVFVFHSGQEEDEEDRRLQSNYMAKLMGNTTRPAILLSYLVVDPGEGNYNTYVSETSGMHDIDPSDDDRWCEYILYRGLRRTGYARVARGTITDTELQVGKFQVLSEQA-LVEHSDSMYEYGHMSEPEYEDMKFPDKFLGEGERGHFYHVFDEPRYYL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : * : ** .* *::*** : ::* * :.:*.**:* :. : . . .: : * *:::* .: *: :* :.:. .:: : :** : : :.: . : ::** : ::*:: : : ** * ... . :*:. :. . :. : :. : :* . *: ...****:* * :: : * . ** .*: .. ** * *:*. . : . : . : :::. . : *. : * : :: :.. * . . .: .*:: : .* .*: *** * **: :.:*. :* :. * : *:::: *: :: : :.* :. .: *: ::. . ::*.**.::** **: *.. :* :*::: *.: :**:*:.: :**.*** *...*.:*:****... **** : **::***.* ******* **:**** *:: . ***..* * *:.**: **:**: ::**: . :. .*:*.*:. **. :* ::: . ::***.:* *******:**** * ****:::. ::*:*:*:.**:: .: ::. : :: :.: : : :* . *.. .. .:. :: *:*::", "identical_positions": 163, "similar_positions": 257, "identity": "16.86%" }, { "cls_id": "homologset.agr.MGI:2444133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PRF0-1", "uniprot_id": "HTR5A_MOUSE", "id": "Q5PRF0-1", "name": "HEAT repeat-containing protein 5A", "aln": "------------------------------------------------MELAHSLLLNEEASNQLGAVQKAEFIFEWLRYLEKLLLATNREDVREKQKTLVGQLLSLLNSSPGPPTRKLLAQDLAILYSVGDTVSVYETIDKCNDLIRSKDDSPS------YLPTKLAAVVCLGSLYKKLGRILANGFTDTVVNILKAMKSAESQGRYEIMLSLQSILTGLGAAAAPCHRDVYKAARSCLTDRSMAVRCAAAKCLLELQNEAIFMWSTDVDSVATLCFKSFEGSNYDVRISVSKLLGTVLAKAVTAKHPG-AGSKQS------------ARRVSLEEVLELLGAGFLRGSSGFLRASGDMLKGNSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNLAAFLSHILSLVSQSNPKATQTQIDAVCCRRCVSFI--LRATLGGLLGEKAQIAAAKEICQAVWRLKKVMDAALSDGNVETRLSSTDVAASQHVLVCALQELGNLIHNLGTTAAPLLQDSSTGLLDSVISVVLHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLAILKSSP-----EAVTGFSSAVAALLGSVTHCPLGIPHGKGKIIMTIAEDLLCSAAQNSRLSLQRTQAGWLLVAALMTLGPAVVSHHLTRVLLLWKCVFPASPRDLETE------KSRGDSFTWQVTLEGRAGALCAVKSFISHCGDLLTEEVIQRLLPPLPCAVDLLTQLSSILKTYGSSLKTPSIVYR--QRLYELLILLPPETYKGNLCVILKELAAELTAPDT------QAAASTCLLPALCHPDDLLILSPLLQETDHRFIEEQLLLGN-----------GVACGSLEYDPYSIYE-------------------------------KDVEGDSVPKPLPPALSVISSASKLFGVVCATVDEAQRVLILEQLLNSIKHTKGA--RQQTVQLHVVSAISNLLKYVAGS----KQSLGP-EVRRLVLTLVLGALESPTPLLRCA--ASEAWARLAQVADDGAFTAGLAQLSFDKLKSARDVVTRTGHSLALGSLHRYLGGIG-PQHLSSCIGVLYTLSQDSTSPDVQTWALHSLSLTIDSAGALYHVHVESTLSLIVMLLLNVPP-------------THAQVHQSLGRCLNALITTLGPELQGSNTSVSALRTSCLLGCAVMQDHPGCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLC---------VNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAIMLARD-GRD--AAADANLREVG-LEGALLALLDRETDESLCQDIRETLHHMLTSMAVGKLTLWLKLCKDVLAASAD--------------FTAVTCVDTMQEEEGDRGDDASVLT-RGDDKPHPFSNPRWATRVFAADCVCRIINQCENANRAHFDIALAQEMKKRDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLDTLLVVIRRFADIAEPEFPGHVILEQYQANVGAALRPAFTSETPPDITAKACQVCSAWIASGVVSDLSDLRRVHQLLVSSLTKIQAGKEALSQ----LYNESASTMEILAVLRAWAEVYIIAVQRH----------KNHKQALKTTVNSEDSMRNGSSSAAGLLDLVCTDLATLSKLWLAALQDFALLTLPAEFASQLPTEGGAFYTAETSKSAKLHYHDSWALILHAAALWLTSTGF--ADPDEGGANLSRPVTPTSMCQGSSSSGAAVKSPEDVYTDRFHLILGISVEFLCSLRSDASLESIMACLRALQALLDVPWPRWRIGSDQDLGIELLNVLHRVILTRESPAIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGASEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLAGSPGG-------------KASKPKTLLEEGSRLVAAALAILAELPAVCSPEGSISILPTVLYLTIGVLRETAVKLPGG----QLSCTVTASLQTLKGILTSPMARAEKSHEAWTSLLQSALATVLD-CWSPVDGA-QEPDEVSLLTAVTVFILSTSPEVTTVPCLQNRCIEKFKAALESKDSVVQMKTCQLLHSIFQYPKPAVSYPYIYSLASSIVEKLQDIARRKPEDATELQLCQEGIKLLEALVAIAEEEHR-------AQLVACLLPILISFLLDENALGSATSVTRSLHDFALHSLMQIGPRYSSVFKRVMASSPALKARLEAAVKGNQESVRVD-PPSKHAKNLARNS---SIQLKTNFL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LG41-1", "uniprot_id": "A0ABK0LG41_RAT", "id": "A0ABK0LG41-1", "name": "HEAT repeat-containing protein 5B", "aln": "------------------------------------------------MELAHSLLLNEEASNQLGDVQKAEFVFEWLRYLEKLLLATNRDDVREKQKALVEQLLSLLSSSPGPPTRKLLAQNLAILYSIGDTFSVYETIDKCNDLIRSKDDSPS------YLPTKLAAVVCLGSLYKKLGRILANGFTDTVGNILKAVKSAESQGRYEIMLSLQSILTGLGAAAAPCHRDVYKAARSCLTDRSMAVRCAAAKCLLELQNEAIFMWSTDLDSVATLCFKSFEGSNYDVRISVSKLLGTVLAKAVIAKHPGGAASRQS------------TRRVSLEEVLELLGAGFLRGSSGFLRASGDMLKGSSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNLAVFLSHILSLVSQSNPKATQTQIDAVCCRRCVSFI--LRATIGGLLGEKAQIAAAKDICQAIWKLKKVMDAVLSDGNLETRLSSTDVAASQHMLVCALQELGNLIHSLGTTAAPLLQDSSTGLLDSVISVVLHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTTLKSSP-----EAVTGFSFAVAALLGAVTHCPLGIPHGKGKIIMTLAEDLLCSAAQNSRLSLQRTQAGWLLISALMTLGPAVVSHHLPRVLLLWKCVFPVSPKDLETE------RSRGDSFTWQVTLEGRAGALCAVKSFISHCGDLLTEEVIQRLLPPLPCAVDLLTQLSSILKTYGSSLKTPSVVYR--QRLYELLILLPPETYKGNLCAILKEVAAELTAPDS------QVAASACLLPALCHPDDLLILSPLLQETDHRFIEEQLLFGN-----------GIACGSLEYDPYSIYE-------------------------------KDVEGDSVPKPLPPALSVISSASKLFGVVCANVDEAQRVLILDQLLNSIKHTKGA--RQQTVQLHVVSAISNLLKYVAGS----KQSLGP-EVRRLVLTLVLGALESPNPLLRCA--AAEAWARLAQVVDDGAFTAGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGIG-PQHLSSCIGVLYTLSQDSTSPDVQTWALHSLSLTIDSAGALYHVHVESTLSLIVMLLLNVPP-------------THAQVHQSLGRCLNALITTLGPELQGNNTSVSALRTSCLLGCAVMQDHPGCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCEILLDNSVLVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVMLARD-NRDNNPAADTNLREVG-LEGALLALLDRETDGSLCQDIRETLHHMLTSMAVEKLSLWLKLCKDVLAASAD--------------FTAVTCVDTMQEEEGDRGDDASVLT-RGDDKPHPFSNPRWGTRVFAADCVCRIISQCENANSAHFDIALAQEMKKSDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLDTLLVVIRRFADIAEPEFPGHVILEQYQANVGAALRPAFTSETPPDITAKACQVCSAWIASGVVSDLGDLRRVHQLLVSSLMKIQAGKEALSQ----LYNESASTMEVLAVLKAWAEVYIIAVQRH----------KNHKQTLKTTINSEDSVRSGSASAAGLLDLVCTDLATLSRLWLAALQDFALLTLPAEFASQLPVEGGAFYTAETSKSATPHYHNSWALILHAAALWLTSTGF--ADPDEGGANLSRPVTPTSMCQGSSSSGPAVKSPEDVYTDRFHLILGISVEFLCSLRSDATLESITSCLQALQALLDAPWPRSRVGSDQDLGIELLNVLHRVILTRESPAIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGASEKETVPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTSGPRD-------------KASKPKTLSEEGSRLVAAALVILAELPAVCSPEGSVSVLPTILYLAIGVLRETAVKLPGG----QLSSTVTASLHALKGILTSPMARAEKSHEAWTSLLQSALATVLD-CWSPVDGAHQELDEISLLTAITVFILSTSPEVTAVPCLQNRCIEKFKAALESKDSVVQMKTCQLLHSIFQYPKPAISYPYIYSLASSIVEKLQEMDRRRPGDAAELQLCQEGIKLLEALVTVADEEHR-------AQLVACLLPILISFLLDENALGSATSVTRSLHDFALQTLMQIGPRYSSVFKNVMASSPALKARLEAAVKGNQESVRVD-PSSKQAKNLGRNS---SIQLKTSFL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86XA9-1", "uniprot_id": "HTR5A_HUMAN", "id": "Q86XA9-1", "name": "HEAT repeat-containing protein 5A", "aln": "------------------------------------------------MELAHSLLLNEEAYNQLGEVQKAEFIFEWLRYLEKLLLATSRNDVREKQKTLVEQLLSLLNSSPGPPTRKLLAKNLAILYSIGDTFSVHEAIDKCNDLIRSKDDSPS------YLPTKLAAVVCLGSLYKKLGRILGNTFTDTVGNILKAMKSAESQGRYEIMLSLQNILNGLGAAAAPCHRDVYKAARSCLTDRSMAVRCAAAK------NEAIFMWSTDLDSVATLCFKSFEGSNYDVRISVSKLLGIILAKAVISKHPGTAASRQS------------IRRVSLEEVLELLGTGFLRGSSGFLRASGDMLKGTSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNFAAFFSHILSLASPSHPKATQTQIDAVCCRRCVSFI--LRTTIGGLLGEKAQLAAVKDICQAIWKLKKVMDAVMSDGNLETRLGSTDVAASQHMLVCALQELGNLIHNLGTTAAPLLQDSSTGLLDSILSVILHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTGHKSSP-----EAVTGFSFAVAALLGAVKHCPLGIPHGKGKIIMTLAEDLLCSAAQNSRLSAQRTQAGWLLISALMTLGPAVVSHHLARVLLLWKCVFPASPKDLETE------KSRGDSFTWQVTLEGRAGALCAIKSFVSHCGDLLTEEVTQRLLPPLPCAVDLLTQLSSILKMYGSPLKTPSVVYR--QRLYELLILLPPETYEGNLCAILRELAADLTAPDI------QVAASTFLLPPLCHQDDLLILSPFLQETDHRFIEEQLLLGN-----------GVACGSLEYDPYSIYE-------------------------------KDVEGDSVPKPLPPALSVISSASKLFGVVCAHVGETQRLLILEQLLDSIKHTKGA--RQQVVQLHVVSSVSSFLKYVAGS----KGCLGPEEMKRFALTLVMGALESPNPLLRCA--AAESWARLAQVVDDGAFTAGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGISSSQHLNSCIGILYTLAQDSTSPDVQTWALHSLSLIIDSAGPLYYVHVEPTLSLIIMLLLNVPP-------------THAEVHQSLGRCLNALITTLGPELQGNSTSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLC---------VNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVMLAKD-SREE-LTPDANIREVG-LEGALLILLDKETDERLCHDIKETLNYMLTSMAVEKLSLWLKLCKDVLAASAD--------------FTAVTCVDTMQEEEGDKGDDASVLTTRRDEKSHPFTNPRWATRVFAAECVCRIINQCENANSAHFDIALAQEMKKRDSRNDFLVLHLADLIRMAFMAATDHSDQLRLSGLEMLLVVIRRFATVPEPEFPGHVILEQYQANVGAALRPAFTSETPPDVTAKACQVCSAWIASGVVSDLNDLRRVHQLLVSSLTKIQAGKEALSH----LYNESASTMEILAVLKAWAEVYIIAVQRH----------KNHRQPLKTTTCLEDGIRNGSCSSDGLLDLVYADLGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENAKLHYYNSWALILHATALWLTSTGFVVADPDEGASNLSRPVTPTSMCQGSSS-GATIKSPEDVYTDRFHLILGISVEFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELLNVLHRVILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGSPGV-------------KATKPQILLEDGSRLVSAALVILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGG----QLSSTVAASLQALKGILSSPMARAEKSRTAWTDLLRSALTTILD-CWDPVDETHQELDEVSLLTAITVFILSTSPEVTTIPCLQKRCIDKFKATLEIKDPVVQIKTYQLLHSIFQYPNPAVSYPYIYSLASCIMEKLQEIDKRKPENTAELEIFQEGIKVLETLVTVAEEHHR-------AQLVACLLPILISFLLDENSLGSATSIMRNLHDFALQNLMQIGPQYSSVFKSLVASSPALKARLEAAIKGNQESVKVKIPTSKYTKSPGKNS---SIQLKTSFL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJX9-1", "uniprot_id": "A0A8M3AJX9_DANRE", "id": "A0A8M3AJX9-1", "name": "HEAT repeat-containing protein 5A", "aln": "------------------------------------------------MEQAHSLLLNEEACSQLPEHQRAEFVFEWLRFLKKLLPATDRADVKQKQKRLVEQLTTVLTSSPGPPTRLLLAQCLALVYRVGDSLTSSLTVDRCNDIIRSKDDSPS------FLPTRLAAVACLGALYEQLGRLLINSFKETTTNLLKAMRSAESQGRCEIMLCVERILRGLGVSAVSCHRDIYKAARTGLTDRSMAVRCAAAKCLLELQREAVFLWSTELENVATLCFRALEGSNYDVRVSISKLLGTLLASALEPRQAI--APRPG------------SKRSSLEEVMELLSSGFLRGGAGFLRASGDMLKGTSSVSRDVRVGITQTCVVFVSILGGVWLETHFSRLLSLLMEWAS--HTRATQYPADAVSCRCCVSFI--LRATLGTLLGEKAQIAAAKEICQVISKQKRVVDASLHEGNMETRVSPADVAASQHVLVCALLELGSLVQDLSSTAAPLLQDTGIGMLDTVISVLLHPSASARLASAWCLRCIAVGMPAQVAVLLDRCVERLNALKSCP-----EAVAGYSAAIAALLGAVQLSPLGISHSKGKMVMTLAEDLLRSAAQNSRISIQRTQGGWLLLSALSTLGSTVMEHHLPRLLLLWKCAFPLSVKDVEME------LRRGDSFTWQVTLEGRAGALCAIKSLVVHCKELLTDDVICCFVPLLSCAVALLTQLPSIIKSYGNQIKNAATVFK--LRVYEILKLLQPKIYEESFGTVLKQLLNDLTGPEI------TACAERNLLPSLCYSQDLALLGPGLQDMDQRYIEEQLHGG------------GSGGGTLEYDSFTIFE-------------------------------KSQE---VPTPLPPASALTVAAVQLFGVIFPHLSVQQRAQVLEQFCEFVRQLKGA--RQQTVQIHVTAAFFCTLKSLASS----RRELGPEEVQRPALSLLLGALEGSNPLLRCM--AAEGLARLVQVLNDPGFTVSLTLMSFDKLKTARDAITRTGHALALGTVYRYLGGISSPQYLSACVGVLFTLSQDNTSPEVQMWALHALSIVVDLAGPLYHSHLEASFTLVLRLLLSTPH-------------THVEVQQSLGRCLNALITSVGPDLQGEGAGVCAVRTSCLVGCAVMQDSQDCLVQAQAISCLQQLHMFAPRFVNLSSLVPSLCEILLDYSVLINLCSSYLSLRRAVVACLRQLAQREAVEVSEHAVALVKELPRRDNTQLDVTIKEVG-LEGALFSLLDRESDPRLCRDIQETLVHMMSSAAESKLAHWLKLCKDVLSASAD--------------SAAAASVETQQEEDGDRYDDSSAFH-AKSESSGPFNNLRWSTRVFSMECVCRIIAQCENRDSAHFNMALAQEQRLHES-TDFLVLHLADLIRMAFMASTDHSDQLRLAGLQTLLVIIRKFSNVPEPEFPGHVILEQYQANVGAALRPAFHVDAPPNVTAKACQVCSAWIASGVISDLRDLRSVHQLLASSLAKVQVGRDVPSQ----LYNESTFTMESLAVLKAWAEVYITAVQGS----------RQRDSPVSHQQQQSEEAGTAGQAGAGLLKLVQTDLATLSRLWLAALQDHALLTLPPHYSSHLPSTGGSFYTAETVEQARPHYYSAWATILHATALWLNSTGF--IVVDEGPANLSRPVTPTSMGQ--STSLSNVKSPEDINSDRLHLILGISVEFLCSPHSGDQMENIHSCLQALQALLEVPWPRSKVGNDQALSVELLSILHRLIVTRESPSIQLAVLELVQQIICAAQEHVREKRHSAEVDDGAAEKETVPEFGEGRDTGGLVPGRSLVFGALELCLSTLVRKLPQLSPKLTGSPTG-------------RGGQTCSLSATDCRLVTSALAILSELPSICSPEGSVSVLPTVLYLLLGVLKEAVKGSVGT----ESGQLVSGILQALRTLLTSPMSRAEKSRGAWTQLLQCALHTLLE-SWS-TDKVEPGVDEVTMLTSLTIFLLYASAEVTSVEPLQTRCIQTFRASLDSKDPVVLSRSYQLLLSLFQGPAP-VARPFILALGGRLVSQLEEAEKSRPQGPAELQAVQDAIRALEALVFAADETHR-------PQLVAVLLPILISLLLDENALASAPAASRLLHESALRDLMRIGPQHSAVLKALMASAPHMKARLEAAVKGNQESVNSK---AQAPPAISKNTP--SIQLKINFL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KGF6-1", "uniprot_id": "A0A0B4KGF6_DROME", "id": "A0A0B4KGF6-1", "name": "HEAT repeat-containing protein 5A", "aln": "MENLNFARTPQFLRKVISEARRSFINSDHFSASSTRGRSETEEEAISEMELAHTLILNEDALKQLPEHKRPVFELEWLRYLEKALPLVSKAEIKASQKKLVQQLSERIQGAPGPPIRKLIASALATLFSVGDTFMLFDTVNACNDILKNKDDSPS------YLPTKLAAICVLGSMYEKLGRMMGRTYEDTVQILIRTLRNAESQARIEIMHTLEKVSAGMGTAIANVHKDIYKAAKHCLLDRVMAVRVAAARCILKMIYSAPFLYQTELESLGTLCFRAFDGSNYEVRCAVAQLLGTLLAYTQQLAEAATSKKKQGQAVAIQAGKGATQRLVSLDEALGILMSGFLRGGASFLKGTGEIIKGSSGVNREVRVGVTHAYVVFVQFMGSVWLERQLSTFLAHVLDLVA--NPKAACSHVDAVYSRKCISFI--LRSTIGKMLGEKAQSAACKELVHLVAKQMNSIDFNPEN----AKDSNQETLFSQHLLVCALQELSSLLIGLGTTAQNLLGDQSLQAIDATCAVLVHPCAAARLAAAWCLRCACVAVPGQITPLIDRFVEAIEQMRSSP-----EAMAGYSCALAAILGSVRYSPLGIPHTKGKVVFNCAEELLRSASQNSRMSLHRTQAGWLLIGAIMTLGSPVVKGLLPRMLLLWRNSFPRSNKELESE------KARGDAFTWQVTLEGRAGALSVMHSFLLNCPDLLNEDITRRLLTPIESALAMLVNLASVLKSYGTQLKAPAAMVR--LRLFETLTLLPANALEASYTHLLRMLVSEFTLSDN------AANTTNSLLRTLCHGDDSIILGTWLQETNHRTIEDQMEPNRKVDGEHLQPNSAAGSGALEHDPCCLYRPRSAQGNGSSSNGSSATSTGGSNGGGGSNIQQISKAQQCPGPLPLGVAVIDMAVTLYGTIFPKVANKHRLQMLEHFTECIRQAKSS--RQEAVQMNIFTALLCALKNLTDS----KTSLGQEDVRKSATALIVASLTSANSTIRCA--AGEALGRLAQVVGDSHFTAELAQNSFDKLKSARDVVTRTGHSHALGCLHRYVGGMGSSQHLSTSVSILLALGQDSASPVVQAWSLYALAQIADSGGPMFRGYVEATLTLCLKLLLTVPH-------------AHVDVHQCVGRVVNALITTVGPELQGGGGAVATMRGSFLCSAALLQSHSDPLVQAEAIGCLQQLHLFASKSLQLEELVPTLVG---------MLACNYFILRKASVSCLRQLAHREAKEVCELALTINAE------QLPDLVITEYG-LPGLLFSLLDTETDAEMLRNIHDTLTSMLQMLAADNLSSWLSLCKNVLTVAVEGGLNDDPAAGEQSKSKEAGGEDDEEDEEEEYADDVTEYRAEENTSTHPAVQPRWPTRVFAAQCVRRIIASCEAASSVHFDLLQAKEQQLIRSRGDYLILHLAELIRMSFMAATSDSDQLRLEGLRTLQEIIDRFANVPEPEFPGHLLLEQFQAQVGAALRPAFAPDTPSHVTAAACEVCSAWIGSGVARDIGDLKRVHQLLVSSLDKLSS-KTNSTQ----LYNESMATLEKLSILKAWAEVYIVAMIGNGKAPASLLNLQSQQSGFQSLTNLETDSDVPDSRGESLLGLVQPELHNLSTHWLSAMKDHALLLLPAEFQSQLPHDGGAFYTTDTINSSKPHYMTSWPPILYASALWLRDEGF------------ARHLDTSEAAAESNNNQITHGS---LSADRFHMIFGICMEALCSMRSSERPRNIVSCLRSLHSIFDSDWARRQLVKDRALTIELCHVLHRQILTRDELLVQLLCVEILKQTIRAAREDLERKR-----DDNANSEDGKGGERHGEDDS-MQPGSSHVYAVLEVCLCLFVRQIPTMNPTRQGAGGSGLQLDFAYAKMATGSSFFSVLGDENGLLVSSGLQCVEQLMDLCTPKGALAILPTVLYMTTSIVKEIANKSAIDSTILANTCAVKSALQCLRSVCVHKWAKVEETTEEWQQLLQSALATIVDLTKTAGDNEERKVDEVTMLLAITVFILHTPASVVATPSLQYPCINHFRQCLQSENLSVKLRCIETTRSIFARAELKTATPYIHALAPRIIESLYAESSKVPTSELELQVTLESIVTVEQLIDLSEPQNRNMNLLQDIQMLTLLVPVLIGFLAEPSRLRTLPKYQRQLHDQALQWLLKIGPKYPQEFKALMGQTPELRQKLEAAIRSQQQSINIAQKASEAQRNLLAKPQKPTIKLKTDFSNFQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39526-1", "uniprot_id": "LAA1_YEAST", "id": "P39526-1", "name": "AP-1 accessory protein LAA1", "aln": "-----------------------MANRSLKKVIETSSNNGHDLLTWITTNLEKLICLKEVNDNEIQEVKEIHTQLDEFVRYISVLENTDDLELHSVFISLSQLYTISIWRLKDEYPGVVFDSAAFLTNVLCEEDVSIDDGDTDPNQKKKKKKSSTKKKKYIYSPAKDIACTILVQLFENFGSSISSLIPLLFNAIFKNLKKIMEKSKYYHATFMTTLLQLFNAILRNSN-----NDDKILDPATYAKFSKLSKTVFDSISTDEKDFSVTFVSVLIECWTAHFKQTNFIREHSHDIIETIYSRFTEGEIGVYGFANDET------------RIFTAKSLAEILFDYYFSKNILTLQEVWSIYVK-IFLNCDTRDVESGCFESIIHLINLNLLADNTFLSNSKYLDIVLSLSGVFSSYEVNNRSMNTLSRYLRYFQHMHEVILPHLNDSAKTQMLYYILGCSDTYQSSSKSDSASNFKYSIDAKPETQWLTLLQLDFTYVLISDLGSTFT-TEENTVKEIRDKLVDLATCEIFTIRVHTVEILKVFLNNCPEYLSETIENSLRALSTDFKSTGKFIFHKNHGHAFIIANLIKGAESDYISYELIMRITVFSTSFIKNNTTSTSSNLYFKGLLCWILLIGLMNYKDEQYLKLQIPQLFLFWKVLLTHTYTYHDEDELYKNLEIRNHALTCLLTYLSNTTIDKEMAKQVSYLLTKCSNFNHSIDLKSKNIDNALLHNENRILQVYLKLEKYINSDFNSSLLILIVKNFSDPNLYTESSSSVLGSLKDIGNRKVSNKDDMESNIVLESSINTLLRQNNGFAFGLSSKITGDRIVNLSMSSAYKYDES-----ISGSWPSKDYNWYNIFEVEVSKPISPILSLDSLILLYG----------SGSYSQIDRYAPQVTTSLIDSSMELFSSVFPFLNSKIQYSIMETLNLSMFSKMTTPLRSVAVAANVCSALHNALRIMQENNLELDYSVGQLIIESIKKIQFFNDIFLTKIKADCVGLLTAAIARTLGDEERQKFLTEQSRIFIKNVADMDEPYLRMFHVLSLATIFKYN---SQYANFEEYFDVIFALMRD-PHPVVHSWSLKAMHILLEKHLVIDLKTAALLLSSMEELLVQDKYGIYGRSTLRCNYNRDFNSHVAIGEISRTLTETVGPNFLELNTKVLDSFRNITLSMLISNNILNSITSIKMFENIATFKMKNILNYEIFILASKSIIKS---SIVTGIGSSYFDTTFTGSNELISRTSSLKGAFENFDLLTLLY----KLQMEEFFMKEMENLSWRYLALFPNSGSVKNYFTEWILHTFKRDNHWFDKLYSIFNMSLGRLFQSYN------------------RDVSALLEVNGLKKSSEKEIK---GEEEESIANVNQLTDTDAGGLDSENLQWKSRQIILNLILMLCLESEKYENLLLALSNKIADLIKISFRGSTVRNEGMKLTGLHILNFVLKNYSTMRDPQVPGSSILEQQEAQITSALMPAFSKGSSPTVMSFAITVAAEVLASNIMPPD-KLGRISQLLIDLLGNFKDPNSGIRIGEAIIVTPKAKRKIELAVLDAWAEVVQRSITSS---------------------------------NDALFSFTRKYWSILVPLWIISLREYMMIKYNDNDSTVQVKNDSKENSLIEPRSTKIELY---------EPVWLN------------------FVEALGCTLDSDVQVILASLNDEELEYFLFILFSQCLEAIVKNIDDHSVK--MQVLPALHNVLKSNLCIKSIFED-DIITEVVEIMDRLISTGDSKEEFLLVDIISDLIIGYSKCN--------------------------ATPETFLQDIDKLYELLRLLMTIISERLPFIKYNVLTSEED---------------DNEIKISPTDISLLKKTFIAFESNISNFDNMFKVDLYSCLLFIIGKIYECSHREVIIP-----------IILPLFKALVKALTESEDEKNIVLLEIFYGSIKDVIY----------HKLDSKNKVATILILLSNGYSKLSFQELNQCANILSEALNNPATQPIALQGFKRIISNIFKYPLLQYFMKLVIKRFFQDIQTNDSLSQASIKTKLIIQFSEEVIKQDHQKASLS-------------------IALCLSFFAAYH-----SAYTEKIDNEVASGIVALAKLDKNSFKEAISSTISPQQKAIIGSVMEAYVKSQSLGSVEEAFQLKSFD---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : *:* .:: :. :: : . * .. ::: * : . :: . : : : : :.*..*.: : *:: * * :::::* : ::: ::. .:.: : : :.. : * * :: :.. . .: *: : .. :* .:: : : . : : .. :* :: . *: .: :. :.* : :: :. * : : :. . : : . :: :: :* . : * : : : . : : . :* : : * *: .*.:* : * : : *: :. *: * :: ::. :. : ... . *.: :* :: .. :. ::. : ::: .*.: : **:. : . :. :.:::*:*: :. : : : *..::* :* ..: : . : .: : :* : ::: * . * . : : .: . :* : . . : .* :: :. : ..* :: .: . . : ::: ::. . . :: : *:. : . : : ::: : : : *. .* :: ::. *: : . :* :. .. : .. * . .* * . : :.:: : * * :*. :.:* . :. ..:: :* :* . * *: *:* :: : : :: **: . : : .:*. .:* ::**:: . : . . : :. . :.. : : : ::: :: *.. : . *: : * . . . : : : : * * : *: . . :* :.:. . * : : . : : .. . . . . : . * . : . : . :: : . * . . * ::*:**:::* .:* .: ::* ** * :: .:: : :*:.** :*** :*:: :** *** :.. : : * *.: :.*.: .* : *** . * :.. . : . . *::* ***** :: .*: :. * *: ::::. :: . : .. : ..: . .:** : . . :.:::. .:* : . .. . * :*: ::. : .* : *: ::.* * * :. * : * :: . : . . :: *.: : : .::* :. . . : . *: : . . : : . :*:: : . * :: : ::. .:: :: :: *. . : :: ::: ..: * * : . . .:* . : :. :: : * . : :.: :.:: . . :.: . :: :. :* :..: : : . : : ", "identical_positions": 142, "similar_positions": 584, "identity": "6.26%" }, { "cls_id": "homologset.agr.MGI:2444136", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9V7-1", "uniprot_id": "D4A9V7_RAT", "id": "D4A9V7-1", "name": "Methionine--tRNA ligase, mitochondrial", "aln": "MLRQCALWVLTRTPAGR---------GCRRYSSCSPSASGDAREARAYFTTPIFYVNAAPHIGHLYSALLADALCRHRRLRVPGSGSTRFSTGTDEHGLKIQQAAATAGLA-PIELCDRVSAQFLQLFREAGISSTDFIRTTEARHRVAVQHFWGVLEARGLLYKGIYEGWYCASDECFLPEAKVTRQVGPSGDPCPVSLESGHPVSWTKEENYIFKLSQFREPLQRWLRNNPQAITPEPFHQVVLQWLE--EELPDLSVSRRSSHLHWGIPVPGDDSQTIYVWLDALVNYLTVVG----------------YPDA----------DFKSWWPATSHIIGKDILKFHAIYWPALLLGAGLRPPHRICVHSHWTVSGQKMSKSLGNVVDPRTCLDRYTVDGFRYFLLRQGVPNWDCDYYDEKVVKLLDSELADALGGLLNRCTAYRINPSGTYPSFCAACFPSEPGLMGPSVRVQAEDYALVNAVATLPKLVAGYYNDFQIYKALEAVSSCVRQTNGFVQRHAPWKLTWESPA-DAPWLGTVLHVALECLRVFGTLLQPVTPNLADKLLSRLGVSTTERSLG----ELYFLPRFYGHPCPF-EGRKLG-PDTGLLFPR-LDQSRTRLVKAHRT------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q499X9-1", "uniprot_id": "SYMM_MOUSE", "id": "Q499X9-1", "name": "Methionine--tRNA ligase, mitochondrial", "aln": "MLRQCARWVLTRTRFGR---------GCRRYGSCSPSASGDAGEARAYFTTPIFYVNAAPHIGHLYSALLADALCRHRRLRVPGSASTRFSTGTDEHGLKIQQAAATAGLA-PIELCDRVSAQFLQLFREADISSTDFIRTTEARHRVAVQHFWGVLEARGLLYKGIYEGWYCASDECFLPEAKVTRQVGPSGDPCPVSLESGHPVSWTKEENYIFKLSQFREPLQRWLGNNPQAITPEPFHQAVLQWLE--EELPDLSVSRRSSHLHWGIPVPGDDSQTIYVWLDALVNYLTVVG----------------YPDA----------DFKSWWPATSHIIGKDILKFHAIYWPALLLGAGLRPPHRIYVHSHWTVSGQKMSKSLGNVVDPRTCLDRYTVDGFRYFLLRQGVPNWDCDYYDEKVVKLLDSELADALGGLLNRCTAYRINPSGTYPSFCAACFPSEPGLTGPSVRVQAEDYALVTAVATLPKLVAGYYNDFQIYKALEAVSSCVRQTNGFVQRHAPWKLNWESPE-DAPWLGTVLHVALECLRVFGTLLQPVTPNLADKLLSRLGVSTTERGLG----ELYFLPRFYGHPCPF-EGRKLG-PDTGLLFPR-LDQSRTRLVKAHRT------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96GW9-1", "uniprot_id": "SYMM_HUMAN", "id": "Q96GW9-1", "name": "Methionine--tRNA ligase, mitochondrial", "aln": "MLRTSVLRLLGRTGASRLS--LLEDFGPRYYSSGSLSAGDDACDVRAYFTTPIFYVNAAPHIGHLYSALLADALCRHRRLRGPSTAATRFSTGTDEHGLKIQQAAATAGLA-PTELCDRVSEQFQQLFQEAGISCTDFIRTTEARHRVAVQHFWGVLKSRGLLYKGVYEGWYCASDECFLPEAKVTQQPGPSGDSFPVSLESGHPVSWTKEENYIFRLSQFRKPLQRWLRGNPQAITPEPFHHVVLQWLD--EELPDLSVSRRSSHLHWGIPVPGDDSQTIYVWLDALVNYLTVIG----------------YPNA----------EFKSWWPATSHIIGKDILKFHAIYWPAFLLGAGMSPPQRICVHSHWTVCGQKMSKSLGNVVDPRTCLNRYTVDGFRYFLLRQGVPNWDCDYYDEKVVKLLNSELADALGGLLNRCTAKRINPSETYPAFCTTCFPSEPGLVGPSVRAQAEDYALVSAVATLPKQVADHYDNFRIYKALEAVSSCVRQTNGFVQRHAPWKLNWESPV-DAPWLGTVLHVALECLRVFGTLLQPVTPSLADKLLSRLGVSASERSLG----ELYFLPRFYGHPCPF-EGRRLG-PETGLLFPR-LDQSRTWLVKAHRT------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q9I2-1", "uniprot_id": "A0A8M9Q9I2_DANRE", "id": "A0A8M9Q9I2-1", "name": "Methionine--tRNA ligase, mitochondrial", "aln": "MSSPCCVIASTKLIIHRLCRHVQHRRLPHAYSIAHFCTDRSQSPKAYYITTPIFYVNAAPHIGHVYSAVTADCLHRYKLLQRYNS---RLATGTDEHGLKIQQAAGSAGKD-PLNFCTEVSESFKHVFQRCGISYTDYIRTTEKRHRQAVEHFWTVLLSKGYIYKGTYEGWYSTPDESFLTETQVTDSTDSEGRRIKVSTESGHKVEWMNEDNYMFRLSDFRTQLLHWLRSNPNTIQPVKFQHLVLQWLED-DDIPDLSVSRQKSRLQWGIPVPGDPEQTIYVWLDALVNYLTVVG----------------YPQN----------HSK-WWSVVHHVVGKDILKFHAIYWPAFLLAAGLALPQKIYVHSHWTVKGKKMSKSIGNVINPLESIEKFTVDGLRYFLLRQGVPDSDCDYYDDKVMKMCNSELADALGGLLNRCAAPSLNPTQVYPRFSTSCFP----AVGPSGKAVSEDYRMIEAVSALPGIIEQHFENLYVYKALEAIGACVRLTNGFVQRHAPWRLDRNNPE-EQQWLDTILHVSLECLRIYGILLQPVVPDLADKILSRLGVTPEERSWN----SLNFLNKFQGRECAL-EGRALG-PDLGVLFSR-LERSQIKGKTTKKGTQPKSKS-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFL5-1", "uniprot_id": "SYMM_DROME", "id": "Q9VFL5-1", "name": "Methionine--tRNA ligase, mitochondrial", "aln": "-------MLIRRIKCLR-------------YLGTRYNSS-------HYVTTPIFYVNAAPHIGHLYSAVIADAHCRYQRLRYPEQ-DVRLCTGTDEHGTKIQQAASLHGVP-VAKYCDDISQRYREVFRSASIQQDDFIRTTEDRHKRAVANFWRTLHTRGHIYSAAYSGWYCVSDETFLTDSQLRLDEATG---TRYSLESGHPVEWTEETNYMFRLSQFQDDVRHWVKTEAR-VRPAKFEKILLDTLS--EPLPDVSVSRPSNRVHWAIPVPDDDSQTVYVWLDALVNYLSSVG----------------YPDE----------KFSAHWPPAQQVIGKDILKFHGIYWTAFLLAAGLEPPGQLYVHSHWTVDGQKMSKSKHNVVDPLQAAQQYTMEGLRYFLLREGVAHSDGNYSHVKAQRILNSELADTLGNLLSRASAKSLNPGQIYPSPSAEHLA-------DLLRSLDVAKRLQDSLLQLSERCESHYECNHFHLVADTTMAALHAANNFFESSKPWTLKAGAPDGNQARLETIIAMTMDALRLSGIVLQPIIPQLANRLLDKLSVPTAQRGWNYLAESFATSPNSSNSPAGLGESRQLDGQTSALLFQRILEETSAKEVKEQKPQPAKRSKSKKKERRETMS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22438-1", "uniprot_id": "SYMM_YEAST", "id": "P22438-1", "name": "Methionine--tRNA ligase, mitochondrial", "aln": "--------MQCRSIVHR------------LYSKVS------------HVTTPIFYPNAKPHLGHLYSSLLSDVYHRWQLFKGNLS---FFTTGTDEHGLKIQCASESNGFDQPKKFVDKLYPEFVQLDKIYGINYTRFIRTTDPDHIENVMKLWELCLKNGYIYMGEHKGWYSISDETFYPESKVIKDPKNDG--KYLNTESKNEVVYQSETNYFFRLSLFNKKIVDHIRKNPDFIFPASKRDQILKELETGGTLPDLSISRPSARLKWGIPTPNDPSQKVYVWFDALCNYLSSIGGIPSILSNATEVVSRHYSDKSNVKGQLLIPYPKEVQRNTIHVIGKDIAKFHTVYWPSFLLAAGLPLPRQIVVHGHWLCNGMKMSKSLGNVVDPIDMARYYGADIVRWFLLENSKLEEDGDFQEAKLYETR-ELLVSKWGNLINRCCGSKFNIERAVMKFSDKANFQFQEIFQNEPIVSERIENLAKLLNKSQEVFDEKIAIFQYPQLLRHVWSIINDANTLVQNSKPWERELDQQD-------NIIFLAMETSRILSILCQSIIPSLSQSFLDRIDVSKEKRTIN---YARLGSDKTYGKQSNK-KGREVPLKKIPFRLQE--EQTNMRS------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * :.****** ** **:**:**:: :* * : :: : ******* *** *: * : : : .: : .*. :****: * * ::* .* :* . :.***. .** * .:::: . . ** : * : .* **:*:** *. : : :. : * .. :*. *. :**:*:** . :::*.**.*.* .*.:***:*** ***: :* *.: . . :::**** *** :**.::**.**: * :: **.** * ***** **::* : : .*:***.:. . * :: . * . . *.. *.*:.*. . :* . : : : :. :* :.: ** .:: :::: *: . : *.: *.*:: :*.::.*. :* . . . . :.* : . : . :.: ", "identical_positions": 130, "similar_positions": 155, "identity": "20.0%" }, { "cls_id": "homologset.agr.MGI:2444148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9QDM8-1", "uniprot_id": "A0A8M9QDM8_DANRE", "id": "A0A8M9QDM8-1", "name": "", "aln": "-----MSKRPPNRRGIKFEVGASLEAR----DSLKNWYVANIEKIDYEDEKVLVHYRQWSHRYDEWFDWASPYLRPVERVQLRREARQDDSFIPGFHVNDRVLASWSDCRFYPAKVLAVNKDASYTVKFYDGVVQTVKGIHVKPFTKER------RKKLSDQNGEKPVIQQAEKEIQENEANGDKQAAGQTNCVPEKDE---DGISEVNGEEGEQMR-IKVEN---ESVKEERDLEEIGQHNYSKSLVKKGSGFEEKEEEVMVKMEDSALFDS-----------------------------NVNFSESTVKRNETEETDVLAQ-------QKKEEVEEQCLVHDKKARRQRIK-------------RKRRLSMA------------------RRS-SKKNKTDSEKSHNDGKPNNQQTQGKEPDSLHLTQ--PSNGTSASQAQCQSE---TFKPTA-----VRKQAFHNP--NRFSREPLYRVIRNQPPPVLSINLDHNLYKCNTPGCSKSFRKAKLLHYHMKYYHGEECPIEP--------EQTREMDKKTTLNSHDGSKKRCVTSRECARVTVKNRS---LAPPTASTQNYQQWPLLKDKTRENQLDDTMQRCYNKERDRRFMEMES------------VKERNRLKEKQRRDFLRIKLKEKKK-IRKTTSD--------------------------------------------EDSISDWSSESCGWSEDEMEADLDVITSPLSCSSVASTTESQETVRCVCEADEENDFMLQCEECLYWQHGTCMGLLEENVPERYSCFICRDSSGL-ERRVRGQRQSLRYWYDRDWLSTGHMYG-LSFLEN-YSHQNG--------KKIAATHQLLGDVQHVVEVLSGLQLKISVLQ----NQTHPDLKLWRQPWKPTE--RSRMKS-----KALHDAKTVSS-----------------------SAGLETIENKE----AFSSSFQD-YISSEHCYQKPQTLYQVLEPRLVLKTRVES---------LLEDRLHSTERVPMNEQHYNGDMLKTSNSQ--LFN--HSKVIGEKCEAGADGGGDKSG------AQP----------------QQWKVNLLDHIETVQEEVTHRMDFIERELDVLENWLDCTGELEPPEPLDRLPELKHSIKQLLSE--LGKVQQVALTCAT--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2B947-1", "uniprot_id": "A0A8M2B947_DANRE", "id": "A0A8M2B947-1", "name": "", "aln": "-----MTKSPPNRRGIVFEVGAQLEAR----DTLKNWYAANIEKIDYEDEKVLIHYRQWSHRYDEWFDWSSPYLRPVERIQLRKQGLNERQCASGFQVNQKVLASWSDCRYYPAKILSRDKDDFYTVKFFDGIIKTVKGIKVKPFRKQS------SDGRSNQQARK-RADQNEKELKPKE-NGNSRHNSSRHSVSDHDG---ESESEADEDTTVMDESTDLQN---GGEKESTETKMVNDSEVSSAEHQPSEDQNQPSEDKTENLEN-GNVEI-----------------------------KIEEEEEEEMDGGQEEAKVLHNGIDK-NDEHKGEASDESPSLPKRTRSRTADGK-EAEMVNGPELRKRRASTG------------------QTSPAKRSRANSSTDRNTQTPIKPVKSDSVPDTLDIKDEKTSPAGKPAPAEEAGS---TPELAA-----ALKRQVHLPTTNKYSREPLYRVIKNQPPPILSIELDHNPFKCKMAGCLKSFRKASLLHYHMKYYHAQSDPSPPR------CVQTRSSDKQSPSQETPRRRRTVSASHHTPSPLSDSKSGHSLSPPAVGIKHRQRSATLGAERSKE--NQVFNRSLHDDRD-WVAKETA------------LKERERLREKRQREFFRIKLKKKKKKKRKSKSDSHSTEESIGPKPLPCNLNSAHKLPLSLTHRSYTGHGPEKMLSQGEDSSSDLSSDSPVWSEDESDTELDLN-VPLSEQGVETVTHSSEIVRCICEVQEENDFMIQCDECLCWQHGTCMGLYEDSVPDSYSCYICRDPP--------AQRQSQRYWYDKDWLSSGHMYG-LSFLEENYSHQNS--------KKVTAAHQLLGDVHRVFEVLNGLQLKMSILQ----TQAHPDLKLWRQPWKHADGLRRRMAGDSGIATPLPPSPPEMG-----------------------ENEFETLKSEAPSPMETHCSFQDSYISSEHCYQKPRTYYPAVERRLVVETRGGS---------ELEDSLRSTEDLLEMAEQRYGTQLDHDQHK--LADRSFSKELESRMKRLVSAEQEKSCGVEIKEEEPDPVTPDPKPDPDLVLHQQWQLNLLEHIEAVQDEVTHRMDLIERELDVLESWLDYTGELEPPDPLARLPQLKHRIRQLLTD--LGTVQQIALCSSSS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BLG0-1", "uniprot_id": "PHF20_MOUSE", "id": "Q8BLG0-1", "name": "PHD finger protein 20", "aln": "-----MTKHPPNRRGISFEVGAQLEAR----DRLKNWYPAHIEDIDYEEGRVLIHFKRWNHRYDEWFCWDSPYLRPLEKIQLRKEGLHDEDGSSEFQINQQVLACWSDCRFYPARVTAVNKDGTYTVKFYDGVVQTVKHIHVKAFSKDQNIVGNARPKETDHKSLSSSPEKREKFKEQRKVTVNVKKDKVEKALKTEKR---PKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENEREYSGDAQVEKKPEKDLVKNPQENLKEPKRKRG-----------------------------RPPSITPTAVDSNSQTLQPITLELRRRKISKRSDTPLKRPRLDKNSPQEQSKKRSENSDKDLSRRRSSRLSTNGTREILDPDSIVPDLVHTVDTNPLPDKSPSAKDSAEGQLKSPLEAGQVSSALTCHPIGDGLGAADLELNCKSMGENTMKTEP-----VSPLAEVQEVSTVEVPNTLKKVDDSVTLNVPAVDLDH-KFRCKVLDCLKFFRKAKLLHYHMKYFHGMEKSPEPEEGPGKTHVQTRGSAVPDKTSQESLTRKRVSASSPTAKEKEKTKE--KKFKELVRVKPKKKKKKKKKTKPECPCSEDISDTSQEPSPPKTFAVTR------------CGSSHKPGVHMSPQLHGSDNGNHKGKLKTCEED----------------------------------------------NLSESSSESFLWSDEEYGQDVDVTTNPDE-ELEGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQHGVCMGLLEENVPEKYTCYVCQDPP--------GQRPGFKYWYDKEWLSRGHMHG-LAFLDQNYSHQNA--------RKIVATHQLLGDVQRVIQVLHGLQLKMSILQ----SREHPDLQLWCQPWKQHSGEGRAHPRHIHITDARS-EESPSY-----------------------RTLNGAVEKPS----PLPRSVEESYITSEHCYQKPRAYYPAVEQRLVVETRGSA---------LDAAVSPLCENGDDSLSPRLGWPIDQDRSRGDIDPKPSSPKVREYISKNVLPEETPARKLLDRGGEG-----------LVSSQHQWQFNLLTHVESLQDEVTHRMDSIEKELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLTD--LGKVQQIALCCST--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZQB7-1", "uniprot_id": "D3ZQB7_RAT", "id": "D3ZQB7-1", "name": "PHD finger protein 20", "aln": "-----MTKHPPNRRGISFEVGAQLEAR----DRLKNWYPAHIEDIDYEEGRVLIHFKRWNHRYDEWFCWDSPYLRPLEKIQLRKEGLHEEDGSSEFQINQQVLACWSDCRFYPARVTAVNKDGTYTVKFYDGVVQTVKHIHVKAFSKDQNIVGNARPKETDHKSLSSSPEKREKFKEQRKATVNVKKNQVEKALKTEKR---PKPPDKEGKLTCPEKGRVSEKSLPKNEKEDKENISENEREYSGDAQVDKKPEKDLVKSPQETLKEPKRKRG-----------------------------RPPSITPTAVDSNSQTLQPITLELRRRKISKRSDTPLKRPRLDKNSSQEQSKKRSENSDKDLSRRRSSRLSTNGTRETLDPDLIVPDLVHTVDTNPLQDKSPSAKESAEGQLESPLEAGQVSSALTCHPIGDGLGAADLELNCKSMGENTMKTEP-----VSPPAEVQEDSAAEVPNTLKKAGDFVKLHAPAVDLDH-KFRCKVVDCLKFFRKAKLLHYHMKYFHGMEKSPEPEDGSGRTHVQTRGSTVPDKASQESLPRKRISASSPTAKEKEKNKE--KKFKELVRVKPKKKKKKKKKTKPECPCSEDISDTSQEPSPPKTFAVTR------------CGSSHKPAVHMSPQLHGSDTGNHKGKLKACEED----------------------------------------------NLSESSSESFLWSDEEYGQDVDVTTNPDE-ELEGDDRYDFEVVRCICGVQEENDFMIQCEECQCWQHGVCMGLLEENVPEKYTCYVCQDPP--------GQRPGFKYWYDKEWLSRGHMHG-LAFLEENYSHQNA--------KKIVATHQLLGDVQRVIEVLHGLQLKMSILQ----SREHPDLQLWCQPWKQHSGEGRAHSRHIHITDARS-EESPSY-----------------------RTLNGAVEKPS----PLPRSVEESYITSEHCYQKPRAYYPAVEQKLVVETRGSA---------LDDAVSPLCENGDDPLSPRLGWPIDQDRSRGDIDPKPSSPKVRECIPKKVLLEETPARKLLDRGGEG-----------LVSSQHQWQFNLLTHVESLQDEVTHRMDSIEKELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLTD--LGKVQQIALCCST--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BVI0-1", "uniprot_id": "PHF20_HUMAN", "id": "Q9BVI0-1", "name": "PHD finger protein 20", "aln": "-----MTKHPPNRRGISFEVGAQLEAR----DRLKNWYPAHIEDIDYEEGKVLIHFKRWNHRYDEWFCWDSPYLRPLEKIQLRKEGLHEEDGSSEFQINEQVLACWSDCRFYPAKVTAVNKDGTYTVKFYDGVVQTVKHIHVKAFSKDQNIVGNARPKETDHKSLSSSPDKREKFKEQRKATVNVKKDKEDKPLKTEKR---PKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENDREYSGDAQVDKKPENDIVKSPQENLREPKRKRG-----------------------------RPPSIAPTAVDSNSQTLQPITLELRRRKISKGCEVPLKRPRLDKNSSQEKSKNYSENTDKDLSRRRSSRLSTNGTHEILDPDLVVSDLV---DTDPLQDTLSSTKESEEGQLKSALEAGQVSSALTCHSFGDGSGAAGLELNCPSMGENTMKTEP-----TSPLVELQEISTVEVTNTFKKTDDFGSSNAPAVDLDH-KFRCKVVDCLKFFRKAKLLHYHMKYFHGMEKSLEPEESPGKRHVQTRGPSASDKPSQETLTRKRVSASSPTTKDKEKNKE--KKFKEFVRVKPKKKKKKKKKTKPECPCSEEISDTSQEPSPPKAFAVTR------------CGSSHKPGVHMSPQLHGPESGHHKGKVKALEED----------------------------------------------NLSESSSESFLWSDDEYGQDVDVTTNPDE-ELDGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQHGVCMGLLEENVPEKYTCYVCQDPP--------GQRPGFKYWYDKEWLSRGHMHG-LAFLEENYSHQNA--------KKIVATHQLLGDVQRVIEVLHGLQLKMSILQ----SREHPDLPLWCQPWKQHSGEGRSHFRNIPVTDTRSKEEAPSY-----------------------RTLNGAVEKPRPLALPLPRSVEESYITSEHCYQKPRAYYPAVEQKLVVETRGSA---------LDDAVNPLHENGDDSLSPRLGWPLDQDRSKGDSDPKPGSPKVKEYVSKKALPEEAPARKLLDRGGEG-----------LLSSQHQWQFNLLTHVESLQDEVTHRMDSIEKELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLMD--LGKVQQIALCCST--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VGA4-1", "uniprot_id": "MBDR2_DROME", "id": "Q9VGA4-1", "name": "Protein MBD-R2", "aln": "MGRRCCVANCPSTSRLLEHNGVTYHSFPLDPIIRAIWIKNSRISLERQITKSVLVCSRHFRRLDFNTIRNGKYLLKPRVFPTVFPWGKMDTAEIEADQRALQHASVEGTTETPGNAQSSTNDDVIKATVDQIVAQILSESAERKATEEGKTGKAADDVKNTPESGEDANKAAAKEPSGTPVAASSEATVPAPGSASSSNSPLPGTPPKYSNPHNLTIGARLEALSVEGNWLPARIVEVNETEQTLLVRFERNHKLKVSPSTSGSFQEWMAIKSERLRQRLSNRVLPVFELDEKCMARWSGPRKFPGTIRKLLGNDTYEVLFDDGYVKNVRAVHMNKMPKQLPPVQVAEEGASKSPTPVGTPVSSAPVAPKRASTGSLGGSSGSSGSKKSKCAPQRRDWPLLDMASLDIASLGLPEIPHDGEWTCHWVNDQPIGTEGFLIVGEHQKPTVIVQDWRLPPGWIKHMYQRSNVLGKWDVILVSPSGKRFRSKSDLKLFLESQNLVYNPDVYDFSIHRRRAKDIN-AYVYTHGYNPQPPPKPRPMDVSMNSTLDQSITSQHSLPSTPMPVKESQYMEAPVASLMPPAELMSPQTQPADETKPKIEAEILEASEGGTSQLMLADPHVVENGFAFIGGLKVKIQDNLYVCPREDCAKTYRKEDFLLIHIRHYHKEFAEHVSHCPKMQELAVKRTHPSSIDQVEAVP---------------------KNQIPNQQFFAKMHQQDLQQSRSFKRQSVSATATSSTPSDITPTKALLSPKMEPPSVSPTVESGIKQEDVSLDAGPTQSFNPSLSRSCKRARLSPSKRPSGSRKSNRQRSQRRPILSDNPAG-HGLTEQDVEETRQSFNTPTPDTRIDSKKRRSGAATTPISSIDSPAMGDSVSTPSSNDQTDINAALAPPPAETLSKAPQYIKENGELIRIVRMRQEEIINCICEYGEEDGLMIQCELCLCWQHGACNGIVKEADVPDKYVCYICRNPQRGRDSMRFKHDQDWLFEGKLPVAAYHTANPQATKQFELLKRSHTLTGNLLDAKRSMHSLLVKINIARNRCHPKLYLWAKKWDEDNLDSTALTPVKRAKLEAPDLPN----VPQPEAAIDPEECQYRLIEHIKVQQSLVLDRLNDIEAEMDELE-KEDTLDDLKDADISTTKEALATFIKELETMKRLAKLNQVANMKQTLRDSATSK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08923-1", "uniprot_id": "CTI6_YEAST", "id": "Q08923-1", "name": "Histone deacetylase complex subunit CTI6", "aln": "----------------------------------------------------------------------------MESTAIVPKG-----------------PVVGSEDMEKAEVIASGSTDIISTTSTATTTAAIGSVQEESVKQED-------------------VPMEGGEGEVEEEEGETRCICGELDTPDDSG-----------------------------FFIQCEQCSSWQHGYCVSITQDNAPDKYWCEQCRPELHQLFTTDT-------------------------------------------------------------GEARSIYKPVQEKRRQSRRK----------------------------------------ARSAAASKSHAANEAEKSPRNTSNTDDNVDDIGDEEDEVEDEASAVALAKDGNTRSSRRRRRN------SMDDASTDQYSLDPGDSDKKLLDRKRATFMAREEKQ--YQRMLEKALKESRRTSHQEDPESYEN----------------DADIYQGDTDNHNGTTRLQTDVMLTEGKPDSVTNDDMKESLRPSKEQSMEKTNDVEKEASQEKESSTGSAQDTEKTDEPILPLTSIS-------------SSEDDSRKASSRGSKRVSKPARKGNRTRRSNT------------------------------------------------SSDTNQNRRSADIGTDKPVKPRLPPQRTSLNEMRRRVSAILEFISRTQWELS------------------------------------------------------------------EDQSDREE-----------------FVRFVENQHFVEKVDTIYNGYNESLSMMD-----DLTRELLLWEKKYSNNTNAIQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .. : . ... : . :: . . . . : . :.: . . : : . .. : : .: :. *::. . * : : . . . . : . . : . . . : . * . :: . . . . *: : * . ", "identical_positions": 5, "similar_positions": 65, "identity": "0.42%" }, { "cls_id": "homologset.agr.MGI:2444149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q49A92-6", "uniprot_id": "CH034_HUMAN", "id": "Q49A92-6", "name": "Uncharacterized protein C8orf34", "aln": "MSSPLASELSELAALRPGFRLSAPHARVAPRAATHARGRGRASHAGQPRLRSSCPGPSPGKRRVVPSGGAQPRVLPALSSRSHLFPMASHPQTRIQAYLEKNKIGPLFEELMTKLITETPDQPIPFLIDHLQSKQGNRGQLQRTLSGSAALWAESEKSESKGTRRDFRSYDKPWQLNAKKPKKSKSDLAVSNISPPSPDSKSLPRSVEHPKWNWRTKPQSRDFDELNHILQESKKLGKALENLSRSIAISDELDKETVTFNSSLLRPRVIGEWIGREENDADPLAAEMLQPPIPRSKNDQWESEDSGSSPAGSLKMEPKNKGLKQQQQQHKKLLAAMLSQDSFESIHSPTPSVTEEDIDNEDDAMELLEDLNDLRMEGVTTLVPSGSKFNQGRPTYPAEPQAKVTLNICSRCARLQGDNLEERTEESLPILHSPDEKIPDSFDSLPGTEEALME------------------------------------------------------------------EGDEFEKASK---------------------------------------------------------------------------------------------------------------LTGPGEASSGVGHSLKNYMEEDESLKQLQVVHQPWILPSDTESEGVEAEQEKRSADLLLCVPCSSCPTLVYSGL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BZJ8-1", "uniprot_id": "CH034_MOUSE", "id": "Q8BZJ8-1", "name": "Uncharacterized protein C8orf34 homolog", "aln": "--------------------------------------------------------------------------------------MASRQQTRIQAYLEKNKIGPLFEELMTKLITETPDQPIPFLIDHLQSKQGNQGQLQRALSGSAALWAESESSEPKGTRRDFRSYDKPWQMNAKKPKKSKSDLAVSNISPPSPDSKSLPRSVDHLKWNWRTKPQSRDFDELNHILQESKKLGKALENLSRSIAISDELDKETLAFNSSLLRPRVIGEWIGRAENDADPLAAEMLQPPVPRSKNDSWESEDSSSSPAGSLKMEPKTKGLKQQQQQHKKLLAAMLSQDSFESIHSPTPSVIEEDIDNEDDAMELLENLDDLRMEGVTTLVLSGSKFNQGRPTHPAEPQAKVTLNICS---RLQGDNLMERTEDTLQILHTPDEIIPDSLDSLPGTEETLME------------------------------------------------------------------EGEDFEKTSN---------------------------------------------------------------------------------------------------------------LTEPGEASSGA-HSLKSYMEEDESLKQLQVVHQPWLLPSDTESEGIEAEQDKRSAD-LLCVPCSSCPTLIYSGLSVKPAKEVASGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZPH6-1", "uniprot_id": "D3ZPH6_RAT", "id": "D3ZPH6-1", "name": "", "aln": "--------------------------------------------------------------------------------------MASRQQTRIQAYLEKNKIGPLFEELMTKLITETPDQPIPFLIDHLQSKQGNRGQLQRTLSGSAALWAESESSEPKGTRRDLRSYDKPWQMNAKKPKKSKSDLAVSNISPPSPDSKSLPRSVDHPKWTWRTKPQSRDFDELNHILQESKKLGKALEKLSRSIATSDELDKETVAFNSSLLRPRVIGEWIGRAENDADPLAAEMLQPPVPRSKNDSWESEDSSSSPAGSLKMEPKTKGLKQQQQQHKKLLAAMLSQDSFESIHSPTPSVIEEDIDNEDDAMELLEDLDDLRMEGVTSLVLSGSKFNQGRPAHPAEPQAKVTLNICSRCARLQGDNMMERTEDTLQVFPSPDEIIPDSLDSLPGTEETLME------------------------------------------------------------------EGEDFEKTSN---------------------------------------------------------------------------------------------------------------LTEPGEASSGG-YSLKSYMEEDESLKQLQVVHQPWLLPSDTESDGIEAEQDKRSAD-LLCVPCSSCPTLVYSGLSVKQAKEFTSGP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A3KP40-1", "uniprot_id": "CH034_DANRE", "id": "A3KP40-1", "name": "Uncharacterized protein C8orf34 homolog", "aln": "--------------------------------------------------------------------------------------MASLQQSRIQSYLEKNKIGPLFEEMMTKLITETPDHPIPFLIGHLQTKQESPGRIQRTLSGSAALWAEG-SSEYKGTRRDSRGYEKPWQIHPKKPKKSKSDLAVSNISPPSPESKSLPRSILRPTWDWRTKPESRGFDELNHILLESKKLGKALENLSRSIAVSDDFDLDPRAYN-SVLRPRVVGEWVGREEEDLDPLAAEMFQPPVPRAKTEGWTSKDN--SPVGSLKMETKGKGLKQQQQNHKKLLAAMLSQDSFDSMPDSAPSVTEDEMEDEDDAMELLEDLDDLRMEGVTGLLQSGSKFSQGRSSYYTEPQAKVTLNICSRCARLQGDSLTARTEE-EPERHVPEQAVPEVPCPLPTVTETLTATEDLQTASQVTGLRHPVWASDVKPIRGTSPQTARRALQLQDSLFSKELENMGKHLAEVEKDLAKLAEQGKLNRSPNSPHRSLLLPPLFHTTNTLPVLGQTSRPQSPSSLSSKTTGLPLHNPKPTSLMTDRTSPSNSSSRAQTPSRPITPNSLMMRSFTAAGHGNKERVYGRSRSRPVTPTGQITRPILTPPGLSTTDLYGGLWSTLTEDEFYQQLQAVRKPWRIPSDAESDCLDP-PEQDKCEFYTSDPSHSLKTL-----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** *:***:*************:**********:******.***:** . *::**:**********. .** ****** *.*:****::.********************:*******: : .* *****:**.******** **********:****** **::* :. ::* *:*****:***:** *:* *******:***:**:*.: * *:*. **.******.* ********:**************:*: ..:*** *:::::*********:*:******** *: *****.***.:: :************ *****.: ***: *:: :*: .** . *:* * .::::.: ** ** :::. .* . : *** :***.*::** :***:**: ::. :: ..: . *. * ** ", "identical_positions": 273, "similar_positions": 103, "identity": "37.55%" }, { "cls_id": "homologset.agr.MGI:2444151", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BWY2-1", "uniprot_id": "CLC1A_MOUSE", "id": "Q8BWY2-1", "name": "C-type lectin domain family 1 member A", "aln": "MQAKYSSTRDMLDDD-DTTISLYSGTSTVTRRAEPRHSENGTPSSVWRPVALTLLTLCLVLLVGLAALGLVFFQFYQLSNIQQDSITEKDEKLG--NMSRQLQSLQAQNRKLIETLQQVAVKLCRELYNKSGGHRCSPCPEKWKWYGDKCYQFYKESKN-WQSCEYFCLADNATMLKISTQEELDFAMPQSYSEFFYSYWTGLS-RNGSGKAWLWTDGTPYSFELFEIII-DPTNLRNRDCMTIFNGKAYSKDCKELR--RCACERIAGRVVPGELQ----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZGU3-1", "uniprot_id": "D3ZGU3_RAT", "id": "D3ZGU3-1", "name": "", "aln": "MQAKYSSTRDMLDDD-DTTISLYSGTSTVTRRAEPRHSENGTPSSVWRPVALTLLTLCLVLLVGLAALGLVFFQFYQLSNTQQDSITEKDERLG--NMSRQLQSLQTQNRKLTETLQQVAVKLCRELYNKSGGHRCSPCPEKWKWHGNKCYQFYKESKT-WQSCEYFCLADNATMLKISTQEELDFAMPQSYSEFFYSYWTGLS-RNGSGKAWLWTDGTPYSFELFEIII-DPTNLRSRDCMTIFNGKAYSKDCKELR--RCACERVAGRVVPEELQ----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NC01-1", "uniprot_id": "CLC1A_HUMAN", "id": "Q8NC01-1", "name": "C-type lectin domain family 1 member A", "aln": "MQAKYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLVLLIGLAALGLLFFQYYQLSNTGQDTISQMEERLG--NTSQELQSLQVQNIKLAGSLQHVAEKLCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKS-WEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGLL-RPDSGKAWLWMDGTPFTSELFHIII-DVTSPRSRDCVAILNGMIFSKDCKELK--RCVCERRAGMVKPESLHVPPETLGEGD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7Z4-1", "uniprot_id": "E7F7Z4_DANRE", "id": "E7F7Z4-1", "name": "", "aln": "------MQTDKLAED----------VEGNPDRVDPYHQQGKVACAMF-----TVLLLFSFLVIGIVTG----FNFKKSP--------QEDQNRG--LLSDDITPIPFQYK------------------SDKG-----LCSDGWLLYKNTCYLLENVYGT-WKSSKSLCLSRGAHLMVVDSEEELEFIS--RVVQKWTDYWIGLK-RDKMG-KWFWVNGDDYHSNLHFWDE-NQPAHGGMESCVYLKGSD-TVNRKLFH--DSDCSSQRFHICEHQI-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLM0-1", "uniprot_id": "Q9VLM0_DROME", "id": "Q9VLM0-1", "name": "", "aln": "---MYKYATCIFSIF--ALWNFWGVSAKKQDTSTGTNELPKAPMPYYTIENIDMHQQHWFTYNSLRQNG----TLWRIGNMEQRLEMRLQSFQN--QMETKLRALKQQIEP----------------YMENVKMSNKIKMSVFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFS---EETKKKYWVDINSRANDGASWISTLSG-RDVPFLKWKP-NLATNIHNHCVYINSNEMYFENCANDN--YFACQAEQWA-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPS1-1", "uniprot_id": "Q9VPS1_DROME", "id": "Q9VPS1-1", "name": "", "aln": "---MFKYDTYFLYLIVLLDPQGAQENNCPKVSLSERLEKRGEFSLVEFDPLLKFIVKNPHKELLGEIEGLVGHTENKLQPMKSVIPNQSKALLNYLDLHSKLEYLDAALQKAINSLQCS--------LKNTKVMSTGKPHPEFQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRK---QLEARWFWLDIS--NLVDKDQYISLATGKEVSYLKWRHGEPKKSSTANCAYLYAGDYYTYQCSDRN--FFICQAV--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8L7-1", "uniprot_id": "A1Z8L7_DROME", "id": "A1Z8L7-1", "name": "C-type lectin domain-containing protein", "aln": "------MQKSIIFLVLPLCLSSSYSAACEGVESDSQCAAYCYGVLNPCIASMGNLQRRVEACEAAVAIARIALNDRRLDNFGTSTNLQLENQNTSQQLLTHGTAMGRKLEE----------------------------NEIFQQLGSKYYYIEKEEKLNWHDALDKCHKMGGHLASLQSQEELDRFNN--QLNGLNRYWIDVT--NQFNESEFVSVTKGSKANFLSWADGEPTKDGECVDIRTFNGKTTMNDNSCFANLYFICEKSIEI-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . : : . : : . * .. * .. : :.:* :* .: . : . : *. ", "identical_positions": 5, "similar_positions": 27, "identity": "1.74%" }, { "cls_id": "homologset.agr.MGI:2444155", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BNJ3-1", "uniprot_id": "NMNA2_MOUSE", "id": "Q8BNJ3-1", "name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2", "aln": "-----------------------------MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTG-----------------RFIVIGGIVSPVHDS------------------------YGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQT-----TCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIG--------QPQHENTQPIYQNS---NVPTKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLG--TVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0HA29-1", "uniprot_id": "NMNA2_RAT", "id": "Q0HA29-1", "name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2", "aln": "-----------------------------MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTG-----------------RFIVIGGIVSPVHDS------------------------YGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQT-----TCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIG--------QPQHENTQPIYQNS---NVPTKPTAAKILGKVGESLGRICCVRPPVERFTFVDENANLG--TVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADADRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BZQ4-1", "uniprot_id": "NMNA2_HUMAN", "id": "Q9BZQ4-1", "name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2", "aln": "-----------------------------MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTG-----------------RFIVIGGIVSPVHDS------------------------YGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQT-----TCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIG--------QPQNETPQPIYQNS---NVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLG--TVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PC93-1", "uniprot_id": "NMNA2_DANRE", "id": "Q6PC93-1", "name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2", "aln": "-----------------------------MTENTKTHVILLSCGSFNPITKGHIHMFEKAREYLHKTG-----------------RFIVIGGIVSPVHDS------------------------YGKPGLVPSRHRLTMCQLAVQSSDWIRVDPWECYQDTWQT-----TCSVLEHHRDLMKRVTGCILSNVNTPSTTPVIG--------QPQNE-TSAIYQN-----TVNKSVAIKFWGKMSESLGKICCVRPHMDRFTFVDENANLG--TAMRYEEIELRILLLCGSDLLESFCIPGLWNESDMEVIVGDFGIVVVPRDGADTERIMNHSSVLRKHKDNIIVVKDEIDHPMSIVSSTKSRLALQHGDGHVVDYLSQPVIDYILQSQLYINASG----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06178-1", "uniprot_id": "NMA1_YEAST", "id": "Q06178-1", "name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1", "aln": "MDPTRAPDFKPPSADEELIPPPDPESKIPKSIPIIPYVLADANSSIDAPFNIKRKKKHPKHHHHHHHSRKEGNDKKHQHIPLNQDDFQPLSAEVSSEDDDADFRSKERYGSDSTTESETRGVQKYQIADLEEVPHGIVRQARTLEDYEFPSHRLSKKLLDPNKLPLVIVACGSFSPITYLHLRMFEMALDAISEQTRFEVIGGYYSPVSDNYQKQGLAPSYHRVRMCELACERTSSWLMVDAWESLQPSYTRTAKVLDHFNHEINIKRGGVATVTGEKIGVKIMLLAGGDLIESMGEPNVWADADLHHILGNYGCLIVERTGSDVRSFLLSHDIMYEHRRNILIIKQLIYN---DISSTKVRLFIRR-AMSVQYLLPNSVIRYIQEHRLYVDQTEPVKQVLGNKE", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53204-1", "uniprot_id": "NMA2_YEAST", "id": "P53204-1", "name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2", "aln": "MDPTKAPDFKPPQPNEELQPPPDPTHTIPKSGPIVPYVLADYNSSIDAPFNLDIYKTLSSRKKNANSS------NRMDHIPLNTSDFQPLSRDVSSEEESEGQSNGIDATLQDVTMTGNLGVLKSQIADLEEVPHTIVRQARTIEDYEFPVHRLTKKLQDPEKLPLIIVACGSFSPITYLHLRMFEMALDDINEQTRFEVVGGYFSPVSDNYQKRGLAPAYHRVRMCELACERTSSWLMVDAWESLQSSYTRTAKVLDHFNHEINIKRGGIMTVDGEKMGVKIMLLAGGDLIESMGEPHVWADSDLHHILGNYGCLIVERTGSDVRSFLLSHDIMYEHRRNILIIKQLIYN---DISSTKVRLFIRR-GMSVQYLLPNSVIRYIQEYNLYINQSEPVKQVLDSKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:*: .*::. : . :. : . * :. **. .:. .* * : :::. :: : *. : :*. :. * *: *. :. : *:* : *:. . *:. : .: : . *** . : . : * : * .: *:: ::*:**.*.**:**: * :* ::*:. *:*::* ::* * .:*. :: .:: ::: **:::*: * : :**** ** ::: * *.:.** ** : .**:: : ", "identical_positions": 57, "similar_positions": 106, "identity": "14.07%" }, { "cls_id": "homologset.agr.MGI:2444156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LYV3-1", "uniprot_id": "A0ABK0LYV3_RAT", "id": "A0ABK0LYV3-1", "name": "", "aln": "MAEKRQGAWFGFGFCGFGQALGSGNGQHAVHSPE-PLHAADDVCQVSASWSYTALVTRGGRVELSGSVSCAADGCRDVWASEGLLVVQRNKSGSGTELQ---AWVPGSALQGEPLWVQNLASGAKAQGED----EPGSEPRMGTLPLLPCARAYMTPQPP----------FCQPLAPELRVRQLQLGAEHALLLCEAGQVFSWGGGRHGQLGHGSLEAELEPRLLEALQGLRMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRSGTEK-KTVREE--ELNDDGLRGEEAALADVGAPAHFIAIQPFPALLDLPLGSDAVKASCGSRHTAVVTRTGELYTWGWGKYGQLG-HKDSTSSDQPCRVEYFVERQLEVRAVTCGPWNTYVYAVERENI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTU7-1", "uniprot_id": "RCCD1_MOUSE", "id": "Q8BTU7-1", "name": "RCC1 domain-containing protein 1", "aln": "MAEKRHGAWFGFGFCGFGQALGSGNSHHSVYSPE-PLHASDDICQVSAGWSYTALVTRGGRVELSGSVSGAADGCRDVWASEELLVLLRNKGGSSTEVQ---AWVPGSALQGEPLWVQNLVSGAKGQGED----EPSRESRMGTLPLLPCARAYVTPEPP----------FCQPLAPELRVRQLELGAEHVLLLCAAGQVFSWGAGRHGQLGHGTLEAELEPRLLEALQGLRMAKVAAGGWHSVCLSETGDIYIWGWNESGQLALPTRSGTEN-KAEREEATELNEDGLK-EELAVADAGAPAHFIAIQPFPALLDLPLGSDAVMASCGSRHTAVVTRTGELYTWGWGKYGQLG-HKDSTSLDRPCCVEYFVERQLEVRAVTCGPWNTYVYAMERDKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NED2-1", "uniprot_id": "RCCD1_HUMAN", "id": "A6NED2-1", "name": "RCC1 domain-containing protein 1", "aln": "MAEERPGAWFGFGFCGFGQELGSGRGRQ-VHSPS-PLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQ---VWAAESALRGEPLWAQNVVP--EAEGED----DPAGEAQAGRLPLLPCARAYVSPRAP----------FYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRNLAEDGETVAREATELNEDGSQVKRTGGAEDGAPAPFIAVQPFPALLDLPMGSDAVKASCGSRHTAVVTRTGELYTWGWGKYGQLG-HEDTTSLDRPRRVEYFVDKQLQVKAVTCGPWNTYVYAVEKGKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VD63-1", "uniprot_id": "Q9VD63_DROME", "id": "Q9VD63-1", "name": "RCC1 domain-containing protein 1", "aln": "----MPLLFTGFNAFGQHECVSGDVDCAAGFSELNAPVSTQNQCTISIGWRYAALAFG-RKLCLRGLLDDGPNECVTLEATGNIRALAAADSHCLVLLQSGQLYRVQPKLQAELVAVRLEAAPRSNSGTKRSIFGAAKAPSSPIIEHIACGSHINVAISSENCVYSIPSCLHQFSERQFRVKQLQCGHEHAVLLNANGDVFTWGNGLRGQLGLAELRVEETPQLLEALAGIKITQIAAGGWHSAAISAFGDLYTWGLNCSGQLGLRVMKPGGVLKEPTVFPLPQLQDLPECACSQSGESND------------------DCAPLRVFAGSRHTLLIRRCGRLWVSGWCKHGQLGRQLQDLSYVDAFQALEGITMNPTVDDVLCGPWSTLLHLKCTA--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **. * : :... . .* . : : * :* .* *:*:. :: * * . ... * *: : .: . :* : . *:.* : .: .. . .* . .. . : :.*. . .. : : ::*.:**: * **.:** *:**:** * :**** . *..* *:***** *: ::::*******..:* **:* ** * ****.* . . : :* . .: . .. .: . .***** :: * *.*:. ** *:**** : : * . . : : * * ****.* :: ", "identical_positions": 88, "similar_positions": 106, "identity": "22.11%" }, { "cls_id": "homologset.agr.MGI:2444159", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80VL0-1", "uniprot_id": "ICEF1_RAT", "id": "Q80VL0-1", "name": "Interactor protein for cytohesin exchange factors 1", "aln": "-------------------------------------------------------------MSRRRISCKDLGHADCQGWLYKKKEKGTFLSNKWKKFWVVLKGSSLYWYGNQLAEKADGFVNLPDFTVERASECKKKNAFKINHPQIKTFYFAAENLQEMNMWLNKLGFAVTHKESTTKDE-ECYSESEQEDPETAVEAPPPPSASATSSPVAARRASSSSPKRRETSCSFSSLENTVKAPSRFSSSGSKERQSWLDIVNSSPATEDVGHPLSFAVQVHTLASSEASSCRVSENSSTTPESGCLNSLSSDDTSSLNNSQDHLTVPDRASGSRMTDRDEIKSSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIRTLNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYQQQ-----------VPQDPEVTPQEIMNPTSSDCVENSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DU31-1", "uniprot_id": "ICEF1_MOUSE", "id": "Q5DU31-1", "name": "Interactor protein for cytohesin exchange factors 1", "aln": "-------------------------------------------------------------MSRRRISCKDLGHADCQGWLYKKKEKGTFLSNKWKKFWVVLKGSSLYWYSNQMAEKADGFVNLSDFTVERASECKKKNAFKINHPQIKAFYFAAENLQEMNVWLNKLGFAVTHQESITKDE-ECYSESEQEDPEVAVEAPPPPYASTTSSPVAAQWASSSSPKRRETSCSFSSLENTVKAPSQFSSSGSKERQSWHNIVNSSPATEDAGLPLTFAEQVHTLAFSEASNCQAPENNCITSEGGLLNLLSSDDTSSLNNNKDHLTVPDRAAGSRMADREEIKSSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIRTLNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYQQQ-----------APQDPEVTPQEVMNPTSSDCVENSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWN9-1", "uniprot_id": "ICEF1_HUMAN", "id": "Q8WWN9-1", "name": "Interactor protein for cytohesin exchange factors 1", "aln": "---------------------------------MTSYMAIDGSALVPLRQKPRRKTQGFLTMSRRRISCKDLGHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTVERASECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDE-ECYSESEQEDPEIAAETPPPPHASQTQS-LTAQQASSSSPSLSGTSYSFSSLENTVKTPSSFPSSLSKERQSLPDTVNSLSAAEDEGQPITFAVQVHSPVPSEAGIHKALENSFVTSESGFLNSLSSDDTSSLSSNHDHLTVPDKPAGSKIMDKEETKVSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIRTLNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYQQQR-------ASPAPDDTDDTPQELKKSPSSPSVENSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I513-1", "uniprot_id": "A0AC58I513_DANRE", "id": "A0AC58I513-1", "name": "", "aln": "MSARGVFRGIRYLQVFTCWIQMVEFIIFSSLRAAKTRKMETEADSYPLQDFAAGEFEGDGVMSRRRVSVKDLGQGDCQGWLYKRKESKGLLGWKWKKFWFVLKKCSLYWYTSDMAEKAEGYINLRDFTIEQATECKKKFAMKASHLHVLTLYFAAESMKDMNKWLAKLTQASNEPEPTDSTNGECYSEESDDED-------DEEMCVEYMDQLTPGSLHGCLPPPRSSSSPFQDVIPLVSSVCSRTETQSADSESWQEISS-----------------------------------------------------------------EEDPILKIQQCKGNDGPASDEMEMLYLHLKEASLSPTGALQPFTKRDFRSSFIRRCKDENINDKLHLIRALNSTLKAKEADLQAIEQVLSEPSLNGSKYRQWRDANVLLLQEIGEKHKSDVEKPMVQTRPQRQSLYGPNTAVPAARVYTETSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:* ****:.********:**. :*. ******.:** .***** .::****:*::** ***:*:*:***** *:* .* :: ::*****.:::** ** ** * . *. . : *****..::: . . ::. .. * :* .*..: *.: . ..: * : :* : . :. . :: : . . . .**** ** *::***** * :* **:::*.**::***: .**:*** **:******.** ** *:*:*.:*.*.. ***:*: *.**:*:* ::: *: . : ..: .*.*:", "identical_positions": 134, "similar_positions": 108, "identity": "27.97%" }, { "cls_id": "homologset.agr.MGI:2444167", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZI94-1", "uniprot_id": "D3ZI94_RAT", "id": "D3ZI94-1", "name": "", "aln": "MRPDDINPRTGLVVALVSVFLVFGFMFTVSGMKGETLGNIPLLAIGPAICLPGIAAIALARKTEGCTKWPENELLWVRKLPCFRKPKDKEVVELLRTPSDLESGKGSSDELAKKAGLRGKQLPQGPGEVPMASSITTPTPTEEGECQSLVQSGRQEETSRYLDGYCPSASSLAYSALDAKCSGWDRSDRPEPEDSIFFVPQDSIIVCSYKQNSPYDRYCCYINQSQGRWDHETIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A7E1Z1-1", "uniprot_id": "TM215_MOUSE", "id": "A7E1Z1-1", "name": "Transmembrane protein 215", "aln": "MRPDDINPRTGLVVALVSVFLVFGFMFTVSGMKGETLGNIPLLAIGPAICLPGIAAIALARKTEGCTKWPENELLWVRKLPCFRKPKDKEVVELLRTPSDLESGKGSSDELAKKAGLRGKQLPQGPGEVPMASSVTTPTPTEEGECQSLVQSGRQEETSRYLDGYCPSASSLAYSALDAKCSAWDRSDRPEPEDSIFFVPQDSIIVCSYKQNSPYDRYCCYINQSQGRWDHETIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68D42-1", "uniprot_id": "TM215_HUMAN", "id": "Q68D42-1", "name": "Transmembrane protein 215", "aln": "MRPDDINPRTGLVVALVSVFLVFGFMFTVSGMKGETLGNIPLLAIGPAICLPGIAAIALARKTEGCTKWPENELLWVRKLPCFRKPKDKEVVELLRTPSDLESGKGSSDELAKKAGLRGKPPPQSQGEVSVASSINSPTPTEEGECQSLVQNGHQEETSRYLDGYCPSGSSLTYSALDVKCSARDRSECPEPEDSIFFVPQDSIIVCSYKQNSPYDRYCCYINQIQGRWDHETIV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************************************************************************************************************************ **. ***.:***:.:**************.*:**************.***:*****.***. ***: *********************************** **********", "identical_positions": 216, "similar_positions": 13, "identity": "91.91%" }, { "cls_id": "homologset.agr.MGI:2444169", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A871-1", "uniprot_id": "D4A871_RAT", "id": "D4A871-1", "name": "Leiomodin-3", "aln": "MSEHSGNS------DQEDTLS-----------------------------------------------EELDEDEILANLSPEELKELQSEMEVMAPDPHLPVGMIQKDQTDKAPTGNFDHKSLVDYMYLQKASRRMLEDERVPVSFVQSEENTQKQHEVREKGIASMPQFLKEKLNSEILAKKRQSNGSNNVQETEDDED--EEDEEDEEDDEDEDEGEEGDEDEEDGDGEQANRGKNEAKEQVHNNASICQQPATRAMEEQKATRAMEEQKDTAETKGKGAKKIAKLDPKKLALD-TSFLKVSARPSGNQTDLDGSLRRVRQNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKSFSLANVGADESVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEISRLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKRRQKRQEEQQQQQLKEQRKLIAMLENGLGLPPGMWERLGGPMPDPRMQEFFQ-----PSPGRSLAAQ-EVPFGARKEMIKNPPQPPQYKTDPDSFRVVKLKRIQRK--------------------------SRMPEARES--QEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLNDIRHSNVAYLKPVQLPKELA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QA62-1", "uniprot_id": "LMOD3_MOUSE", "id": "E9QA62-1", "name": "Leiomodin-3", "aln": "MSGHSRNS------EQEDTLS-----------------------------------------------EELDEDELLANLSPEELKELQSEMEVMAPDPHLPVGMIQKDQTDKAPTGNFNHKSLVDYMYLQKASRRMLEDERVPVSFVQSEKNTQNQREVGDKGIKNMPQFLKEKLNSEILAKKRESNGSNNVQEAEDDDEDEEEEEEDDEDEEEEEEDEEDDEGEEDEDGEQANREKNDAKEQIHNNPGTYQQLATKTAHEQ---------KDTSETKEKGEKKIAKLDPKKLALD-TSFLKVSARPSGNQTDLDGSLRRVRQNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADESVAFALANMLRENRSVTTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEISRLLKANTTLLKMGYHFELPGPRMVVTNLLTRNQDKRRQKRQEEQQQQQLKEQRKLIAMLENGLGLPPGMWERLGGPMPDPRMQEFFQ-----PASGRPLDAQ-EVPFGSRKEMIKNPPQPPQCKTDPDSFRVVKLKRIQRK--------------------------SRMPEAREA--QEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLNDIRHSNVAYLKPVQLPKELE-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0VAK6-1", "uniprot_id": "LMOD3_HUMAN", "id": "Q0VAK6-1", "name": "Leiomodin-3", "aln": "MSEHSRNS------DQEELLD-----------------------------------------------EEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDE---EEEDDDDDDEGEDDGEESEETNREEEGK--------AKEQIRNCENNCQQVTDKAFKEQ---------RDRPEAQEQSEKKISKLDPKKLALD-TSFLKVSTRPSGNQTDLDGSLRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEIARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQQQLKEQKKLIAMLENGLGLPPGMWELLGGPKPDSRMQEFFQ-----PPPPRPPNPQ-NVPFSQRSEMMKKPSQAPKYRTDPDSFRVVKLKRIQRK--------------------------SRMPEAREP--PEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLNDIRHSSVAYLKPVQLPKELA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7X0-1", "uniprot_id": "LMOD3_DANRE", "id": "E7F7X0-1", "name": "Leiomodin-3", "aln": "MSERTEQESYTDKIDEDEILAGLSAEELKQLQSEMDDIAPDERVPVGLRQKDASHEMTVRDCTEPESEEEIDEDEILAGLSAEELKQLQSEMEEIAPDERVPVGMRQRDQTDKPPTGSFDHRSLVEYLYWEKESKRMLEEERVPTTLLPSQ-KTNEEHEAKNEDKVEELELVYEEIVEEVEGGQGDAVVDEVIEEVIMEVE----EEDKVCDKPVKTDLDATDPTVTSEDGLQRPSESADANVEAKTDQSGLDTETKVNEEKKEDSTEPAPSSYENWVPEKEERVISKLKIPKLALGGNTFVKKTARPSGNETNLESTLDKIRNNNPSVTDVNLNNIENIPKEMLLDYVNSLKKNRHVKTFSIANTGADENVAFTLANMLKENRSITTLNIESNFITGKGIVAIIRCLQFNETLTELRFHNQRHMLGHHAEMEVSRLLKANNTLLKMGYHFELPGPRMVVTNLLTRNLDRQRQQRMEEQKLQQMKEQRKVMEMYEDSLNLPPGMLEMLGGYIPLSLLQNCQNGAEDIPEDSPEPSPQPSPPHQLCKTQHLAPQQHPPNLSTGNLFEEVQLKKTPKRRDPLLEWNQCDERKDGRPNVHLRSVPKKRSIAREGPVDERANLKDMIKTLKPVPRRREPPKVDLTPRDHLLSEIRQSNVAYLKAVPLPKILESQETSLF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :: :. :::: * **::***:**.**.****:****** :*** :**** *:*****.***.*:*:***:*:* :* *:****:****.::: *: :*::::* :: . : : *:: .*: . : :: .. ::*. : : :*:. *. : : : : . :* *: : :. . : : .:: . : : *:**. ****. .:*:* ::*****:*:*:.:* ::*:*:*.:.::***************:**::***:*:*:**:**.****.***:*****:****:******************:****************************::******.************************* *::**:* ***: **:***:*:: * *:.*.***** * *** * . :*: : * .* . *. . * * * : : *. *:**: :: .: . *** *::****:*********.* ** *::****:**.:**:*.*****.* *** * ", "identical_positions": 281, "similar_positions": 158, "identity": "41.63%" }, { "cls_id": "homologset.agr.MGI:2444173", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUP8-1", "uniprot_id": "D3ZUP8_RAT", "id": "D3ZUP8-1", "name": "", "aln": "MSGAALGLEIVFVFFLALFLLHRYGDFKKQHRLVIVGTLLAWYLCFLIVFILPLDVSTTIYNRCRHAAANSS-----PPENSNVTGVYASVTPAQR-QHPCFKPWSYIPDGIMPIFWRVVYWTSQFLTWILLPFMQSYARSGGFSITGKIKTALIENAIYYGTYLLIFGAFLIYVAVNPRLHLEWNQLQTIGIAAANTWGLFLLVLLLGYGLVEIPRSYWNGAKRGYLLMKTYFKAAKLMTEKADAEENLEDVMEEVRKVNESIKYNHPLRKCVDTILKKCPTDYQEKMGRNMDDYEDFDE---KRNTYPSEKSLVKLHKQVIYSVQRHRRTQVQWQILLEQAFYLEDVAKNETSATHQFVHTFQSPEPENRFIQYFYNPTVEWYWECLLRPWFHRILAVVLSIFSVIVVWSECTFFSTTPVLSLFAVFIQLAEKTYNYIYIEIACFLSIFFLSICVYSTVFRIRVFNYYYLASHHQTDAYSLLFSGMLFCRLTPPLCLNFLGLTHMDASISHQNTQPTAYTSIMGSMKVLSFIADGFYIYYPMLVVILCIATYFSLGTRCLNLLGFQQFMGDNDMTSDLVDEGKELIRREKRKRQRQEEGENRRREWKERYGHNRED-STRNRNVHSDPKESNFSDTTTNWSS---KYTRANNRTER-DRIELLQDAEPLD-FNAETFTDDSLEPESGRYQPGGRYLSMSSSI--IFEDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C561-1", "uniprot_id": "LMBD2_MOUSE", "id": "Q8C561-1", "name": "G protein-coupled receptor-associated protein LMBRD2", "aln": "MSGAALGLEIVFVFFLALFLLHRYGDFKKQHRLVIIGTLLAWYLCFLIVFILPLDVSTTIYNRCRHAAANSS-----PPENTNVTGLDASVTPAPR-QHPCFKPWSYIPDGIMPIFWRVVYWTSQFLTWILLPFMQSYARSGGFSITGKIKTALIENAIYYGTYLLIFGAFLIYVAVNPRLHLEWNQLQTIGIAAANTWGLFLLVLLLGYGLVEIPRSYWNGAKRGYLLMKTYFKAAKLMTEKADAEENLEDVMEEVRKVNESIKYNHPLRKCVDTILKKCPTDYQEKMGRNMDDYEDFDE---KRNTYPSEKSLVKLHKQVIYSVQRHRRTQVQWQILLEQAFYLEDVAKNETSATHQFVHTFQSPEPENRFIQYFYNPTVEWYWECLLRPWFHRTLAVVLSIFSVIVVWSECTFFSTTPVLSLFAVFIQLAERTYNYIYIEIACFLSIFFLSICVYSTVFRIRVFNYYYLASHHQTDAYSLLFSGMLFCRLTPPLCLNFLGLTHMDSSISHQNTQPTAYTSIMGSMKVLSFIADGFYIYYPMLVVILCIATYFSLGTRCLNLLGFQQFMGDNDMTSDLVDEGKELIRREKRKRQRQEEGENRRREWKERYGHNRED-STRNRNVHPDPKESNFSDTTTNWSS---KYTRANNRTER-DRIELLQDAEPLD-FNAETFTDESLEPESGRYQPGGRYLSMSSSI--IFEDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68DH5-1", "uniprot_id": "LMBD2_HUMAN", "id": "Q68DH5-1", "name": "G protein-coupled receptor-associated protein LMBRD2", "aln": "MSGAALGLEIVFVFFLALFLLHRYGDFKKQHRLVIIGTLLAWYLCFLIVFILPLDVSTTIYNRCKHAAANSS-----PPENSNITGLYATANPVPS-QHPCFKPWSYIPDGIMPIFWRVVYWTSQFLTWILLPFMQSYARSGGFSITGKIKTALIENAIYYGTYLLIFGAFLIYVAVNPHLHLEWNQLQTIGIAAANTWGLFLLVLLLGYGLVEIPRSYWNGAKRGYLLMKTYFKAAKLMTEKADAEENLEDAMEEVRKVNESIKYNHPLRKCVDTILKKCPTEYQEKMGRNMDDYEDFDE---KHSIYPSEKSLVKLHKQVIYSVQRHRRTQVQWQILLEQAFYLEDVAKNETSATHQFVHTFQSPEPENRFIQYFYNPTFEWYWECLLRPWFYKILAVVLSIFSVIVVWSECTFFSTTPVLSLFAVFIQLAEKTYNYIYIEIACFLSIFFLSICVYSTVFRIRVFNYYYLASHHQTDAYSLLFSGMLFCRLTPPLCLNFLGLTHMDSSISHKNTQPTAYTSIMGSMKVLSFIADGFYIYYPMLVVILCIATYFSLGTRCLNLLGFQQFMGDDDMTSDLVNEGKELIRKEKRKRQRQEEGENRRREWKERYGHNRED-STRNRNIHTDPKESNFSDVNTNRSAF--KYTRANNRTER-DRIELLQDAEPLD-FNAETFTDDPLESESGRYQPGGRYLSMSRSD--IFNDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P4P2-1", "uniprot_id": "LMD2B_DANRE", "id": "Q6P4P2-1", "name": "G protein-coupled receptor-associated protein LMBRD2B", "aln": "MSGAALGIEIVVVFFLALFLLHRYGDFKKQQRMVLFGTLLAWYLCFLIVFILPLDVSTTIYNQCLIDQEAQTQTPSVSPVLSEQTTANASISPAKSTQRVCYKPWSYIPDGIMPVFWRVVYWTSQCLTWLLLPFMQSYARSGGFTITGKIKTALIENAIYYGTYLFIFGSLLIYVAVHPQWHLSWYELQTIGITAANTWGLFLLVLLLGYGLVDIPRSYWEASRQGHLLIKTYFKAAKLMTEKADSEENLEDVMEEVRKINESIKYNHPLRKNVDTILRKCPLEYQEKMGRNMDDFEDFDD---KQNSYPTERSLSKLHKQVIYAVQRHNRTRVQWQILLEQAFHLEDVAKNETSTSRQFVHSFAPPEPVGWFRRYIYTPTAEWYWECLLKQWFYRVLAVVLALFSVAVVWSECTFFSTHPVLSLFAVFIQLAERDYNYLYIEMACFITIFFLCTCVYSTVFRIRVFNYYYLASHHQTDAYSLQFSGMLFCRLTPPLCLNFLGLIHMDSAISHQAKKQTAYTSIMGSMRVLSFIANGFYIYYPMLIVVLCIATYFSLGTRCLNLLGFQQFMGENEMTSDLIDEGRELLRRERRKRQRIEDGENRRREWRERY-AQRDENAARNRTSMSEMKETNYGETLNANTNRQAKYTRSGSQSGR-DSIELLQDAEPLD-FNAETLTDDPLQSDTGRH-AGGRYLSMSSSRNRIFDDV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IWA8-1", "uniprot_id": "A0A0R4IWA8_DANRE", "id": "A0A0R4IWA8-1", "name": "", "aln": "MSGVALALEVVVVFFLALFLLHRYGDFRKQHRMVLFATLLAWFLCFLIVFILPLDVSTTIYNQCKIDNQVH-----LVPSNSNDNSSNTSVLPTQRIPKTCYKPWSYIPDGILPVFWRVVYWTSQFLTWLLIPFMQSYARSGGFSISGKIKTALIENAIYYGTYLLIFCSLLIYVAVSPQWHLTWYGLRTIGITAANTWGLFLLVLLLGYGLVEIPRSCWRASCHGHLLAKTYFKAAKLMTEKADAEENLEDVMEDVKTVNETIKYNHPLRKCIDTILRKCPVEYQEKLGRNMDDYEDFDD---KGNPYPSKKSLVKLHKQVIYAVQRHNRTKVQWQILLDEAFHLEDVAKNETSPAHQFVHSFPSTETPGWISKYLYTPTMEWYWECVFRRWCYRVLAVVLCVFSAAVVWSECTFFSTQPVLSLFAVFIQLAERDYNYVYIEMACFVTIFFLCYCVYSTVFRIRVFNYYYLAPHHQTDAYSLQFSGMLFCRLTPPLCLNFLGVIHMDSTISHQQRQPTVYTSIMGSMQVLSFIANGFYIYYPMLIVLLCIATYFSLGTRCLNLLGFQQFMGDNDLTSDLVDEGKELIRRERRKRQRTEDGESRRREWRERYGEQRERYSGRNRNAYSELKETD-GSSTDP--------SRAPSRRDRNDKAELLQDVEPLD-FNGE----EPLETDNRRY-PGGHYLSTSASRTRIFDDV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MRQ4-1", "uniprot_id": "LMBD2_DROME", "id": "Q8MRQ4-1", "name": "LMBR1 domain-containing protein 2 homolog", "aln": "-MAYLLSFGIVAALFLASISLYRYGNIPRQHILVTLSVLTAWCFSFLIVFTIPLDVTSTLYRQCVEEHRPTP-----APNVTNTSS--ATVGPPPQ----CQEPWGMVPASVFPNLWRIIYWSSQFLTWLIMPLMQSYLKAGDFTVKGKLKSALIENAIYYGSYLFICGVLLIYIAVK-GESLDWQKLKAIASSASNTWGLFLLILLLGYALVEVPRSLWNNAKPGFALQYAYFKAAKLSTEKAEAEEHVDDILESLQGLSRVIPNNHELRPCLETILRKVPIELQERASRNFARTGGSGMGATSSTILPSEKALVRIHKQVIKSLQTLQRTEALWSVQVQTVLHLEDVAKNIHSSDRRFKSEFPRQRT--QLERICYSASLQWYWECLLKAPFLKTMCVLTATMSAMVVWSELTFFSRHPVLSIFANVIYVAKESYDFFTIEVFSMVVLCYFFYCTYSTILRIRFLNLYYLAPHHQTNEHSLIFSGMLLCRLTPPMCLNFLGLIHMDTHIIPNRIMETVYTQIMGHMDVIGIISNGFNIYFPMCMLAFCLATWFSLGSRALNALGFQQFLQNETIATELVQEGKDLIAREKRRRQRAEEAMARRRDFNRTDQVLGSDYLSKYRSGGPGGLTSSRTPADGLLRDGDGSFDYAAVASSSALGVPRSLSEEINDRFGVSTQVQVGFRDPDYEAETDGRIVGPPPRG--LFDDV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.: :* .:*** : *:***:: :*: :* ...* ** :.***** :****::*:*.:* * :: . :: * * :**. :* .::* :**::**:** ***:::*:**** ::*.*::.**:*:**********:**:* :***:** * * *::*. :*:********:*****.**::*** *. : *. * :******* ****::**:::* :*.:: :.. * ** ** ::***:* * : **: .**: . . . . *::::* ::***** ::* .**.. *.: :: .::******* *. ::* * .. : : *..: :*****::: : :.*: . :*. ***** **** ****:** .* :*:. *::. **: .:: : :: *.***::***.:* ****.****: :** *****:******:******: ***: * : *.**.*** * *:.:*::** **:** :: :*:**:****:*.** ******: :: ::::*::**::*: :*:*:*** *:. ***::.. . : *. . :. : . * * *. . :. . ..*: :. . :*:*:", "identical_positions": 264, "similar_positions": 216, "identity": "37.13%" }, { "cls_id": "homologset.agr.MGI:2444177", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A388-1", "uniprot_id": "A0A8I6A388_RAT", "id": "A0A8I6A388-1", "name": "VWFA and cache domain-containing protein 1", "aln": "---------MAREPEEEETVRTAALVRRCPRCPGWPGAPRPPFWLLCLVACWILGAVADADFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSLVYTEKISNGES-----------------EVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTVSCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQ--------YFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRP--------------------------------------------QSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTYLS---PATSETKRKMSTFVSSVKPSDSPTQHAVGFHRAFQLIRSTSN-NTRFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENGFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGIPDRTALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKP-------CYFGNLLLGIVGVDVNLAYILEDVTYYQDSLAS------YTFLID-DKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIITVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLG----QPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPE---TKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMS--SLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHS----SSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLVDPKGHAP---LEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRSYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGN----LTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSR--CNQRMESGDCFGVLDCEWCVVDSDGKTHLDKSYCAPQKECFGGIVGAKSPY--VDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDEREDDSHEDRG----IISNTRFIAAVMERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCN---------------NDPLSAGVDVGNHDDDLDLDTPPQTAALLS----HKFHHYRS---HHPTLHHS---------------------HHLQAAVTVHTVDAEC--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PDJ1-1", "uniprot_id": "CAHD1_MOUSE", "id": "Q6PDJ1-1", "name": "VWFA and cache domain-containing protein 1", "aln": "---------MAREPEEEETVRPAAVVRRCPRCPGWPGAPRPPLWLLCLVACWILGAVADADFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSLVYTEKISNGES-----------------EVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTVSCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQ--------YFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRP--------------------------------------------QSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADAVRTCSLDQCYKTYLS---PATSETKRKMSTFVSSVKPSDSPTQHAVGFHRAFQLIRSTSN-STRFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENGFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGIPDRTALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKP-------CYFGNLLLGIVGVDVNLAYILEDVTYYQDSLAS------YTFLID-DKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIITVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLG----QPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPE---TKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMS--SLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHS----SSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLVDPKGHAP---LEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRSYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGN----LTNAENRNPSCEVHQEPVTYTAIDPGLQDALQQCVNSR--CNQRMESGDCFGVLDCEWCVVDSDGKTHLDKSYCAPQKECFGGIVGAKSPY--VDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRG----IISNTRFIAAVMERHVHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCN---------------NDPLSAGVDVGNHDDDLDLDTPPQTAALLS----HKFHHYRP---HHPTLHHS---------------------HHLQAAVTVHTVDAEC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VU97-1", "uniprot_id": "CAHD1_HUMAN", "id": "Q5VU97-1", "name": "VWFA and cache domain-containing protein 1", "aln": "---------MARQPEEEETAVAR--------------ARRPPLWLLCLVACWLLGAGAEADFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSFVYTEKISNGES-----------------EVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQ--------YFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRP--------------------------------------------QSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLS---PATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNN-NTKFQANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKP-------CYFGNLLLGIVGVDVNLAYILEDVTYYQDSLAS------YTFLID-DKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLG----QPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPE---TKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMS--SLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHS----SSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAP---VEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGN----LTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSR--CSQRLESGDCFGVLDCEWCMVDSDGKTHLDKPYCAPQKECFGGIVGAKSPY--VDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRG----IISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCN---------------NDPLSAGVDVGNHDEDLDLDTPPQTAALLS----HKFHHYRS---HHPTLHHS---------------------HHLQAAVTVHTVDAEC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F5Q0-1", "uniprot_id": "E7F5Q0_DANRE", "id": "E7F5Q0-1", "name": "VWFA and cache domain-containing protein 1", "aln": "--------MASRSRTGPRFSFAAWSKHSRPNWNNLEISKWSLVALLVFACCGFCG--ADSEFSILEEAQVLAVQMKKLSTQELGVLTMQRIFNSFVYTEKTSNGET-----------------EVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCSIPPSMMEFDGNFNANVSKTVSCDRLSPTVNSRAFNPGRDLNSVLADNLKSNPGIKWQ--------YFSSEEGIFTLFPAHKFHCKGTFEHRSRPVYVAAVRP--------------------------------------------QSKHIVVIIDHGASVTETQLQIARDAALVILNSIDEHDKISVLTIADTVRSCSLDQCYKSFLS---PATSETKRKMSTFISNIKASDSSTQHAVGFQKAFQLLRNTSN-VTRQLTNTDMMIIYLSSGITSRDSSEHEKRATLSAVKEENRHLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSLKYGVQDRSALPVVKGSMMVLNQLSNLETTVGRFYINLPNRMIDVATFSLPYADQMGDGFIMTVSRP-------CYFGNLLLGVVGVDVNLAYILEDVTYYQDSLAS------YTFLID-NKGYTLMHPSLTRPYLMTEAPLHTDIIHYENIPGFPVVRQNILSLPLGSQVIAVPVNSSLSWHMNRLRDPNRDAYNVSYAWKLVQDTSFILCIVYVQPEIPVKQLKNLNTAPSSKLLYHRLDLLG----QPSSCLHFKQLATVESPTVMLSAGSFSSPYEHLSQPE---TKRMVEHYTAYLSDNTRLIANPGLKSSVRNEVMATSHVTDEWMSLMEMS--SLNCYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHA----PSSQMASGYTVAVMGIDFTLRYFYKVLLDLLPICNQDKGNKIRCFIMEDRGYLVAHPTLIDPKGHAP---AEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSIVGDLTNLVHGSHCSKYRLTRIPGTNAFAGIVNETCDALAFCACSTVDRLCLNCHRMEQNECECPCECPLEVNECTGN----LTNAENRNPSCDVHQEPLSLTVIEPSLQDTLPQCINTR--CSQRFTSSDCFGVLDCEWCMVDSDGKTHLDKPYCALQKECFGGIVGAKSPY--VDGMGILDEELASLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLDNERDDRDEDSHEDRG----IISNTRFIAAVIERHTHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCN---------------NDPLSAGVDVGNHDEDLDLDTPPQTAALLS----HKFHPYRHPHMHHPLHLHT---------------------HHLQAAVTVHSVDAEC--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5BI42-1", "uniprot_id": "CAHD1_DROME", "id": "Q5BI42-1", "name": "VWFA and cache domain-containing protein CG16868", "aln": "MWPNSNLNAVLLILAVLACPTSSQHVPLAMANSTSNQVPTDPGFMPLQQSPGSVFFVHHNQQNAMQLRHSMEGKLRNIRNTELRVAKIQEIFDSMHFSSAKGASNTRQASSNDSNVVNPQLQRDLQLFSERLSKKIQKATYVVLELRELLRYNLTKVWQYSYDDEDDESESEMDLEMELEDLHARNTASPTDEHVQLYLNTQIESCQPDYETDLEYGSSSTQSIHYNRQQIQILNYLKSDDARATFLNENNARSLAVNGYISNQLVLLKRRLSRSDAENSNSKPISGNHFKHIYFLSNSDGASASLHFRQLYVSAIKQKFVLFLIDVGSALSAELFDLSKSFVHEMLQLLEDTDKVSLVTVASEANFMSLEAFPAEAGHGIYSATRAHKEEIISFINSLSRAQAFTNHSLGFEYSFELLHRLQQSGMINTAEQPVEFVYITRGLLTNLS---DAMAVLRVVADGQRRLRAPVIINTCAVVLDEKRIMYEKQFLNDVASQNYTKYEIDVASWWPSGQEASELVGRFYVLSKMHAETSLPQTSSRIFGPLFQERYLSDTLEVHPPVVDADSGDVLVSITHAVPPYGVVGVNLYLSDLLEDLLNYPSTTSSAKQGLGYAFLLDRSTGNTLAHPAFPRPLIQRETSYPVNIAYLENATDFSSHIRDRLLREESGNVTTDVYVGRQRLQRTYYWQSVLGFYVLCLVSSGGDTLRNVSSTQRYNLKDTVSNYEPGYYGESMDLLYHRLDLNQGGSAPPKTCRYFRQVATMDAPTLFLSAAAFESPFGFLHNNRPRTQLRHVESIMAYLRDSSGLLANMGLRPSIRHEVGVLYQAMQQLRRRHQDARGSLRSHVIRRYIASVSGVLQLYPGCLLSSSYDPTRRPWFRQAIAQPGKIVSTAPYLDAGGAGYIITIAHTIFEGKAHALHSAQQDRPVAVVALDVPYAFYYRLILEGTPICQLP---HIKCLLFEHEGYLLAHPSMLQPATLTKNQRRPHEHLTHKESYLANDMLNHGQLVRKLGCASYQNRTLQRYYAFNTSLSSILGNVVHG-ERTKYAIALIRGSNLFAAVLNSSCDGGAFCPCSTIDRECLNCKRMDQTDCECPCECPMVGDSSSPSSLMYFANYTRQFPYCPPPSEHFIALPPTTQLLSTLPNCPGSAGICETYSTQRECLGVMGCEWCQLDVDG-NSFSTSFCSSQASCFNGVLASLTPYGELDEMELLAAHNPQREQHAYSAFGPLGGAIVVLVMVIGFAIYCYRHNLDAQTQEHFYVDSVQEENYGLPLSRFNFDDCKAHDEPPLGGGYDHASAQRQLMHAADISPYHVSSGSSYRRPPNGESDHGYSTMTPHEDSSDQQCFTLAEPLLLHDKRHSKSDTMSISTSISSPTNRQQSSSQPNTHPYLSNQPTSKTERYKQVQATPSPCRGTPAGGSVYGQTTLPLEGDKTRPHYILAPVTVHRHMETAES", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : . :: : : :::.: ** * .:*.**:*: ::. . .:: ::* ::::: :*::: ** . ::::. . * . :* . .: ::::. : : : :::. :*:: . * :: * . .*. .*::: *:.*::. *.: :: :. . : *. : : * :.*.::.::* *:::: :::::. . :*. ::: **:*::*:*. .. **: .** *.:: :*:..:. ::: *:*::**. :*:*:: .: :: : ::*:: *: :. * : *.* .: : : *. .*:* * *:: * : * **.*:*.** ** : * : : ::.:: *.. .. .. * . *. : .: : .*. .. *:***:: *: :***: * .: :* *:**:* ..* ** **::.** : *.. .:* : ** . * :: * ..:: : . : . :. * :. . . : : . : : .*.: : * .******** *.:* :*:*:**:::**::***.:*.**: .* : . * ** *** *.: *:** **: *:*:** . :. :: : : **. :::*****: .***::***.*:..::***** *: :*:*:** * *.****.*****::**:***. . . .. .***:.:*.. ::*::::: *:*: :*:*:::*..***:***::::* : ::*:****. :***:*** ::*:* * *:.:**:** * ****: . * *:*** . :** :: * *:* *..::*.:**. ***.** :** ****:**:*.:********: :..: . ::* .: * * .* . . * .:* :* .: *. . :*:**:.**** :* ** . :...:*: * .**.*::.: :** :* * : . : :..**:.*.*: :**: :*:*.***::. ::::*: :.** . :. : *: . ... * * * : . : : . * .. *********:*:***.: * .*.:* ...:.. : : .: *:* . ** * . *: . : *:: *.**** . ", "identical_positions": 329, "similar_positions": 472, "identity": "22.58%" }, { "cls_id": "homologset.agr.MGI:2444188", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSZ6-1", "uniprot_id": "D3ZSZ6_RAT", "id": "D3ZSZ6-1", "name": "Diacylglycerol kinase", "aln": "MLLASPAPRGGCLSQPHHRPVPVTTRWPLSVPRLIRPGRGVTCVPGRPPGGAAGGGADGGKKGEGVGGGDRRERGGFCGRGRRRRLGEPSARGRAGERDPGGCGGGGGGRDQRGGGRARRKPESAGGPVAGPGPEPGRQRQRSRRGRRRQRRRRGPVSVRSGGQRARAGGMEPQHVRPVLGARSPAWEEPESERMAVAGSQHHPQGVAGGAVAGAGAVSP---TAAGPG---EDSSDSEAEQEGPQKLIRKVSTSGQIRTKTSIKEGQLLKQTSSFQRWKKRYFKLRGRTLYYAKDSKS-------------------------------------------------LIFDEVDLSDASVAEASTKNANNSFTIITPFRRLMLCAENRKEMEDWISSLKSVQSREPYEVAQFNVEH---FSGMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDEDGVAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDVYHPVCPLGQCKVSIIPPIALNSTDSDGFCRATFS-FCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPYLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLHKQCQLGVLPLGTGNDLARVLGWGGSYDDDTQLPQILEKLERASTKMLDRWSIMTYELKLPAKASVLPEPAEAT-EEFYMTIYEDSVANHLTKILNSDERAVVISSAKILCETVKDFVAKVEKAQDRTLENTVVAEAVASKCSVLNEKL-EQLLQALHADSQASRVPPGVGPAIPEED-TDTASEE---SLGES--KDQLVNDFGKPSSQKAVKPRE-IMLRANSLKKAVRQVIEEAG-----------------------------------------------------------------------------------------------KVMDEQT------------------------------------------------VQPCEPVSPS-CDYD-TEADE-------------AKE---------------------------------------------DDTKESLS---AKTTPQSPDAQASRG-------------------------------------------------------------------------------------------HSQIDSVAGPAMATTKENLPVLNTRIICP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLRAG---------------------------------------------LAASIAGS--------------------------------------------------------------------------------------SIINKMLLANVDPFG--AMPFIDPDPDSLDGYSEKCVMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQLECDGQYIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDIFAAPSFDDKILEVVAVFDSVQMAVSRVIKLQHHRIAQCRTVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQMLTRDRAFESTLKSWEDKQKCDTG----KPVLRTNLYIHPTADLATEEVS-QMRLCSQAAEELITRICDAATIHCLLEQELAHAVNACSHALNKANPR---FPESLTRDTATEIAINVKALYNETESLLVGR-VPLHLESPHEERVSSALHSVEMELRKLTEIPWLYYILRPNEDEEPPMDCTKRNNKSTVFRIVPKFKKEK-----AQKQKTSLQPVQNWGTEEVAAWLDLLNLGEYKEIFIRHDVRGAELLHLERRDLKDLGIPKVGHMKRILQGIKELERNPPNLV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YXJ0-1", "uniprot_id": "DGKH_MOUSE", "id": "D3YXJ0-1", "name": "Diacylglycerol kinase eta", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGAGSQHHPQGVAGGAVAGASAVSP---TAAGPG---EDSSDSEAEQEGPQKLIRKVSTSGQMRTKTSIKEGQLLKQTSSFQRWKKRYFKLRGRTLYYAKDSKS-------------------------------------------------LIFDEVDLSDASVAEASTKNANNSFTIITPFRRLMLCAENRKEMEVWISSLKSVQSREPYEVAQFNVEH---FSGMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDEDGVAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDVYHPVCPLGQCKVSIIPPIALNSTDSDGFCRATFS-FCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPYLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLHKQCQLGVLPLGTGNDLARVLGWGGSYDDDTQLPQILEKLERASTKMLDRWSIMTYELKLPAKSSLLPEPVAAT-EEFYMTIYEDSVANHLTKIVNSDEHAVVISSAKILCETVKDFVAKVEKAQDRTLENTVVAEAVASKCSVLNEKL-EQLLQALHADSQASRVPPGIGPAIPEEDTVESASDE---SLGES--KDQLVNDIGKPSSQKAVKPRE-IMLRANSLKKAVRQVIEEAE-----------------------------------------------------------------------------------------------KVMDEPA------------------------------------------------VQPSEPVSPS-CDYD-TETDE-------------AKE---------------------------------------------DDAKESLS---AKTTSQSPDAQASCG-------------------------------------------------------------------------------------------HPQTDSVAGPAMATTKENLPVLNTRIICP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLRAG---------------------------------------------LAASIAGS--------------------------------------------------------------------------------------SIINKMLLANIDPFG--ATPFIDPDLDSLDGYSEKCVMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQLECDGQYIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDIFAAPSFDDKILEVVAVFDSVQMAVSRVIKLQHHRIAQCRTVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQMLTRDRAFESTLKSWEDKQKCDSG----KPVLRTNLYIHPAPDLATEEVS-QMRLCSQAAEELITRICDAATIHCLLEQELAHAVNACSHALNKANPR---FPESLTRDTATEIAINVKALYNETEALLVGR-VPLHLESPHEERVSSALHSVEMELQKLTEIPWLYYILRPSEDEEPPLDCTKRNNKSTVFRIVPKFKKEK-----AQKQKTSSQPVQNWGTEEVAAWLDLLNLGEYKEIFIRHDVRGAELLHLERRDLKDLGIPKVGHMKRILQGIKELERNPPNLV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86XP1-1", "uniprot_id": "DGKH_HUMAN", "id": "Q86XP1-1", "name": "Diacylglycerol kinase eta", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGAGGQHHPPGAAGGAAAGAGAAVTSAAASAGPG---EDSSDSEAEQEGPQKLIRKVSTSGQIRTKTSIKEGQLLKQTSSFQRWKKRYFKLRGRTLYYAKDSKS-------------------------------------------------LIFDEVDLSDASVAEASTKNANNSFTIITPFRRLMLCAENRKEMEDWISSLKSVQTREPYEVAQFNVEH---FSGMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDEDGVAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDLYHPICPLGQCKVSIIPPIALNSTDSDGFCRATFS-FCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQCQLGVLPLGTGNDLARVLGWGGSYDDDTQLPQILEKLERASTKMLDRWSIMTYELKLPPKASLLPGPPEAS-EEFYMTIYEDSVATHLTKILNSDEHAVVISSAKTLCETVKDFVAKVEKTYDKTLENAVVADAVASKCSVLNEKL-EQLLQALHTDSQAAPVLPGLSPLIVEEDAVESSSEE---SLGES--KEQLGDDVTKPSSQKAVKPRE-IMLRANSLKKAVRQVIEEAG-----------------------------------------------------------------------------------------------KVMDDPT------------------------------------------------VHPCEPANQS-SDYDSTETDE-------------SKEEAKD-----------------------------------------DGAKESIT---VKTAPRSPDARASYG-------------------------------------------------------------------------------------------HSQTDSVPGPAVAASKENLPVLNTRIICP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLRAG---------------------------------------------LAASIAGS--------------------------------------------------------------------------------------SIINKMLLANIDPFG--ATPFIDPDLDSVDGYSEKCVMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQLECDGQYIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDIFAAPSFDDKILEVVAIFDSMQMAVSRVIKLQHHRIAQCRTVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQMLTRDRAFESTLKSWEDKQKCDSG----KPVLRTHLYIHHAIDLATEEVS-QMQLCSQAAEELITRICDAATIHCLLEQELAHAVNACSHALNKANPR---CPESLTRDTATEIAINVKALYNETESLLVGR-VPLQLESPHEERVSNALHSVEVELQKLTEIPWLYYILHPNEDEEPPMDCTKRNNRSTVFRIVPKFKKEK-----VQKQKTSSQPVQKWGTEEVAAWLDLLNLGEYKDIFIRHDIRGAELLHLERRDLKDLGIPKVGHVKRILQGIKELGRSTPQSEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B2L0-1", "uniprot_id": "A0A8M3B2L0_DANRE", "id": "A0A8M3B2L0-1", "name": "Diacylglycerol kinase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAKRTAFQPLSSSRIPAERKGAAERVPNPECCDFPPQEPEKAAASASGVPAVG-AVGGSGPVVDESSDSEGEQEGPQKLIRKVSTSGQIRSKTSVKEGLLLKQTSSFQRWKKRYFKLRGRTLYYAKDAKAGGVLARWQYRVSRSRVCWRVLSVCWTGARRPPPALGASGSEEGLVAIRSLIFDEVDLSDASVAESSTKNINNSFTVITPFRRLILCAENRKEMEDWISSLKSVQSREHYETAQFNVEH---FSGMHNWYACSHARPTFCNVCRDSLSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDEDGIAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWRCLWCKAMVHTACMDLYPRKCPLGQCKVSIIPPTALNSIDSDGFWKATCPPSCASPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLVNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLHKQCQLGVLPLGTGNDLARVLGWGPSCDDDTQLPQILEKLERASTKMLDRWSIMTYEIKIPPKHSCPATPEEAEDGQLQISAYEDSVAAHLTKILNSDQHSVVISSSKVLCETVKEFVSRVGKCYERGSDSSEESDALALKCAMLNEKL-ESLLQTLNLEAQVLSPTALTTPPIVEEEVEEEELEEEDEDLSEESLTELKENETEKGSAHKLFRPREQLVLRANSLKKALRQIIEQAE-----------------------------------------------------------------------------------------------RMVDEQN------------------------------------------------AHTEEQELQSPSDFRKDSEEE-------------NKDNEKD-----------------------------------------EDTKELETLPLAKSPCSPPERRISRS-------------------------------------------------------------------------------------------TQSCGSFSITPFTTSKENLPVLNTRIICP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLRAG---------------------------------------------LAASIAGS--------------------------------------------------------------------------------------SIISKMLLANIDPFG--ATPFIDPDLDSLEGYLEKCVMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNMMWYGVLGTKELLQRTYKNLEQKVQLECDGQYIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDIFCAPSFDDKILEVVAVFGSMQMAVSRVIKLQHHRIAQCRTVKITILGDEGVPVQVDGEAWIQPPGVIKIQHKNRAQMLTRDRAFENTLKSWEDKLKYD------KPPLRPHLYPQQSVDLATEEEATLIQMCARAAEDLITRICEAAKNYQLLEQELAHAVNASSHAINKTHPK---FPESLTRNTAIEVASTVKALHNETESLLVGR-VPLQLDPPHEELLSTALQNVEVELGKLVEIPWLYHILQPNDEEDPSLEYGKRNSRSGMFRIVPKFKKEK-----VPK-KSSPQSVQRWGTEEVAIWLEQLSLGEYKDTFIRHDIRGSELLHLERRDLKDLGISKVGHMKRILQGTKDLAKSSMVDL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JQ65-1", "uniprot_id": "DGKH_DROME", "id": "A8JQ65-1", "name": "Diacylglycerol kinase eta", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHLKLDTLHVQRSPRGSRRSSP-SSGRSSACSSGSISPVPIIPIISISHDGDE----SESESEIETEPARLFQRRMSTKCTNNLAAIIKEGFLLKHTWSFQRWRRRYFRLKRNMLFYAKDEKCD-------------------------------------------------VFDDIDLSDLCYFECGIKNVNHSFQIITPTRSLVLCAESRREMEDWLGSLKTATAPQRPRGDSFLIEQHDILSNHHHWYATSHARPTYCNVCRDALSGVTSHGLSCEVCKCKVHKRCAAKSIANCKWTTLASVGKDIIEQADGIIMPHQWMEGNLPVSSMCAVCKKTCGSVLRLQDWRCLWCRATVHVACRPQMAVACPIGPAKLSVVPPTSVHSISTDDAWDVASPKGNFSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLISTGPSLGLRLFRHFEMFRILVCSGDGSVGWVLSEIDRFNMHKQCQVAVMPLGTGNDLARVLGWGSSCDDDTHLPQILERYESASTKMLDRWSIMVFEKAIPVPK--TPKMSISTEQEAMLTGMVTSANHHLRFIVETNDTQTLIRSTRNLCDTVDDLVCRISEHHKDDEQLAVKCDILRQKLNMLLDALQEEEIGAHSGDDLIATIRSLIARSIPVTPGSNAYLLNPNISIEKTE-KDQINTKERRNSRSLRSSEKEALQCRANSVKRAIYNVVEHSEPGRPKRYQRKLSITPFEALKLPTASGESTPCTSPLPIIPPINIISPTMETSRLTCISPLPDTRRDSVDENFFNSINLPAPRQFADSRRSSGVEVIQEIEEGANGETVYRKSRMSLTGGANIDDAGNRLSPCSDAGENTPTERKVDFLRVPIHTGEPIVDPLCDYRPHEVFERTYYMTREMDKGKEKDKEKDKPVEIDKEKDTCVEKEGSMPAEKLVHTCNLQVPGVVVTPNPQNVYSSASITIIDTDAQTTTEQSSSDDLGGEASDVLSAISNEECSVASEIFDKQDAGQTVGDIIQNMDASNFTHIDSPETSDETEAMPGESIMDDISSVLGHDITYALQDNTLTDDTTTLCSEHAGPPKPPRKKSLSALSRTQAHPRRRNSSPPRMARLARMDSDDNPQQFGFENIVFEIDNRCDDQKMREPPRYCSLAQFVEGNDIARQSFKQLMLEQHRGGDNDSDYPEHEQTPTNKGANLLATTSEDELSTQTAIKIEIQDIDATVRNLNSSMKPNTILTTSTSPTKKSGHGQDVKRITFDESCKKESFDDVNPNYPQISVVVRPPTPLRGDCIKPTVSLLPVSSGGAMTVSMTCSGMLGVRAMNASEIRRHSSHAPGLAVREFDKDKDRRHSGFNPNQLTLDPEHARFLSSSPAASRRISCGSLFKPNEALPNLQTLKGSKSSLFMGSTLFGFDHLASAEKDKEEKSGKDKEKTPTDETNRKLPIINPLVRLPNWPNLANGGGFISKCLLANADTLCAAVSPLMDPDETLLAGYHEKCVMNNYFGIGIDAKISLDFHNKREEHPEKCRSRARNYMWYGVLGSKQLLQKTCKNLEQRVQLECDGQRIPLPELQGIVILNIPSFMGGTNFWGSSKKDDIFLPPSFDDRVLEVVAVFGSVQMAASRLINLQHHRIAQCQSVQINILGDEEIPIQVDGEAWLQPPGMIRILHKNRVQMLCRNRSLELSLKSWQEKQRQHSISIQRDASSTASEHANSTDEVISERECYVLLNFIEAVSSLVKWVKFLIISHPALQHDLYEVACRASEALESIHPQGKLLEGPSLRTKLVEVIDSSRQLYDDACTLLRDRGHSLILREDLETKLSAALANMEMELKKCSVQKCIDGKLRAYFNVLAPNEESDGRRKSRPFWVRLRSGSTAGQQAFKPPLTNTREAANNWSVNEVVTWLETMQLSEYVDSFLKNDIRGKELLTLGRRDLKDLGVVKVGHVKRILQAIKDLSEN------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : . : * ..*:** * * .: : *::**. . : :*** ***:* *****::***:*: . *:**** *. :**::**** . *.. ** *:** :*** * *:****.*:*** *:.***:. : : . .* :*: :*. *:*** ******:*****::*************** *.*****.:: *********:******: **: *****:*******: ****.************:****:: **.** **:* .*:*::** :::* .:*. .: . ***********************************:. ** ******::*: ******.*************::*::****:.*:*************** * ****:******: * ************.:* :* . : : :: *. ** *::::: .:* *:: **:**.::*.:: : . : : .: : * :* : * *. : : : . * : : .: : .: . : * :* : ****:*:*: :::*.: : ::: :. * . .*: . * *: :.. . : .: .. : * . .. . .. .. *:.*..*. * *:** *::* *.* .:*.* **** *.: . *::*** : ** ************:******:*:*************::* *******:::***:: *****:******** ****.****.:*****: *******.:*:**** .*****::*****:*.*:***.**:*:*********::*:*.*:*** :*:*******:****:*:* ****.*** *:*::* :****::* : . .. . : : : :: :*. . : .*...*:. : : *:::* ... .*.*::. :*: . * . *: . : *:::: :** .* .* * * :* ** .:*:** * : *:. : .. : . . :* * : : . ..: :..:.*..:**. **: :.*.** : *:::*:** *** * ********: ****:*****. *:* .. ", "identical_positions": 530, "similar_positions": 338, "identity": "24.85%" }, { "cls_id": "homologset.agr.MGI:2444198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZY30-1", "uniprot_id": "D3ZY30_RAT", "id": "D3ZY30-1", "name": "Class A basic helix-loop-helix protein 9", "aln": "MLRGTPGLGLRGLKRGEDSVGDLGHSCPEAGRNFGVLRR-----SLAEEEEVAGRKRERPARSKARRMAANVRERKRILDYNEAFNALRRALQHDLGGKRLSKIATLRRAIHRITALSLVLRASPAP--RWPCGHLECH--GQAAHGSSAGDSGFSVPRSVLSPAAPSLARRDTAS-----PLVPPAPRCASCSPNAHLGRPRMMAEVP------SLAQASGGSWR--RCPG---AAPVGSIQWRWG-----SGLGYQHS---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5RJB0-1", "uniprot_id": "BHA09_MOUSE", "id": "Q5RJB0-1", "name": "Class A basic helix-loop-helix protein 9", "aln": "MLRGTPGLGLGGLNRAEDFVEDLGRSCSEAGRNFGVLRRS----SLDEAEEAAGRKRERPTRSKARRMAANVRERKRILDYNEAFNALRRALQHDLGGKRLSKIATLRRAIHRITALSLVLRASPAP--RWPCGHLECH--GQAAQGSSTGNSSFSVPRSAPSPIAPSLTRRDIAS-----PLVPPTPRCASCSPHSHLGRPRVMAEVP------NLAQTSGGNWR--QCPG---APPVRPVSWRWG-----SGLGYQHS---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTU4-1", "uniprot_id": "BHA09_HUMAN", "id": "Q7RTU4-1", "name": "Class A basic helix-loop-helix protein 9", "aln": "MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAP--RGPCGHLECH--GPAARG-DTGDTGASPP----PPAGPSLARPDAAR-----PSVPSAPRCASCPPHAPLARPSAVAEGP------GLAQASGGSWR--RCPG---ASSAGPPPWPRGYLRSAPGMGHPRS---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KNX5-1", "uniprot_id": "BHA09_DANRE", "id": "A3KNX5-1", "name": "Class A basic helix-loop-helix protein 9", "aln": "-MTPVSVCRFSMASRGSFTGSEFSEEEPDGSLQESELDSSDGLGGLNEPEERLIKKRSRPVRSKARRVAANVRERKRILDYNQAFNALRVALHHDLSGKRLSKIATLQRAINRISALSVFLTNNPPVGVAKPCGHLECQPGGLWAEAEPSMQNFLTWHQPLNQHLQTSIHRLSSEQHVFTGPACPPSPHYPCFSPDTQLYPAASVPSPPRYGRIGDVGAYQQGVWGGNHADGYGESLQTLPLPWHMG---YLQDAGLQHCPNTLCYTQCKTVRAL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : . .. ::. .: . : . * . * ** ::* **.******:**************:****** **:***.**********:***:**:***:.* .*. *******: * *.. : :. : .*: * . * *.:*: .. .*.: * . :.. * .:. . * * :. * : . . * * . * :. ", "identical_positions": 81, "similar_positions": 64, "identity": "29.45%" }, { "cls_id": "homologset.agr.MGI:2444207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BX70-1", "uniprot_id": "VP13C_MOUSE", "id": "Q8BX70-1", "name": "Intermembrane lipid transfer protein VPS13C", "aln": "MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAEKEEKSLQDIKQKELCRIEEALQKAAEKGAHSGEFMYGLENLLYKD--VKPGRKRKKHKKHFKKRFKGLDRSKDKPKEAKKDTFLEKLATQVIKNVQVKITDIHIKYEDDI-TDPERPLSFGVTLREFSLLTTNEHWTPCILNEAEKIIYKLVKLDSLSAYWNVGCCMSYRG-----SREHILEQLKREILTSTNIPPDHQYIFQPISASAKLYMNPGAES---ELKTPKLDGNVEVQNIAIELTKPQYLSMIDFLESLDYMVRNAPYRKYKPC-LPLHTNCRQWWKYAIDSVLEVHIRRYTQPWSWSNIKNHRQLLKSYKMAYKTKLTQ-----AKVSEEIQKQIQDLEKSLDVFNIILVRQQAQVEVIHSGQKLRKKSAEAGEKRG--------WFSGFWGKKESKKRDEESSVPETIDDLMTPEEKDKLFTAIGYSENAYN---LALPKQYVAHILTLKLVSTSIIIRENR-----------NVPEILRVQIIGLGTQVSQRPG---------------AQALKIEAKLEHWYVTGLRQQDIVPSLVASIGDTTSSLLKIEFETNPENSPADQTLIVQSQPVEVIYDAKTINAVVEFFQSN--KGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLIIPQTGFHHE-KSNLLILDFGTFQLNSKDQGAQKTANA----------SLEEIIDKAYDKFDVEIRSVQLLFA-KAEENWKKCRFQH-PSTMHILQPMDIHVELAKAMVEKDVRMAKFKVSGGLPLMHVRISDQKIKDALCLINSIPLPQKSSTP--SPE-RQVASIPVLSGGTKAL-LGTSLLLDGVESESDEEFFDAEDGDSQAARTVKASELKKAAEVPNEELVSLLLKFEIKEVVLELTKQQKEEETILVFNVTQLGTEATMRTFDLTAVSYLRKISLDYHDIKGSRKKPIHLISSSDRPGLDLLKVEYIKVDRNGPSFQTTFEKTEQTVKVAFSSLNLLLQTQALLSSLNYLTTVIPSDSQNTGVAKEVQAMPEKQ-KNSPLQKVMVPSRDSDVIGFRLFAKLNAFCVTVCDEKSNIAEIKIQGLDSSLSLQSKKQSLFARLENIIVTDVDPKTIHKKAVSIVGNEVFRFNLDLYPDATEGDSYTDMSTVDGVVALHVGCIQIVYLHKFLMSLLS------------FLNNFQVAKEALSAATAQAAEKAATSVKDLAQRSFRVSVDIDLKAPVIVIPQSSLSTNAVVVDLGLIRVHNRFSLVSGEDTANPPVIDKMEVQLTKLKLSRTAIQPGTSHPDIQLLHPINLEFFVSRNLAANWYHKVPVVEIKGRLDSMNVSLNQEDLNLLFRILAENLGEATEDLDKGKPRIQERGETKACREVSTPQDVHTTQGVPAARVEETRPVDIINVLLNFEIKEVVVTLMKKAERKGSPFHELKILHLGMEAKVKAHDMTAAAYLRNISMRCFHFPDSKGEPLRIVNTSDVSDGILLKLLFIKADSDGPDFKTIHDNTKQKLKVSFSSLDLVLHLEALLSLMDFLSSAIPSSDSSSSEKEPELKPLVGESRSLAIRAVPS-SYEGDAFDLKITAELNAFNIFICDQKSNIAEIKIHGMDASISVKPKQTDVFARLKNIIVMNVD-----SLSIHKKAVSILGDEVFRFQMSLYPDATEGENYGDMSKVDGRLSLKVGCIQIVYVHKFFMSLLSFLNNFQAAKEALSTATVQAAERAASSVKDLAQKSFRLLMDIDLKAPVITIPQSSVSPNVVIADLGLIRVENKFSLVSVEQLALPPVADEMSIQLTQLKLARTVLQADSP------------QHDVEILKPVNMLLCIQRNLSAAWYTQIPGMEIKGELKPMQVALSQDDLTVLMKILLENLGEASSQPSPTQYAQEAARVKR---------DTRSGPDYLKEQ-ELADPKPPGDQTVTLQFDFHFDSLSIILYNSDSSQEPRLSFHNDSFRLGELTLHLMASAGKMFKDGSMNVSLKLKTCTLDDLREGIERATSRMIDKKNDQDNNSS--------------MIDISYSQDKNGSQVDAVLDKLYVCASVEFLMTVADFFIKAMPQSPEN-IAKEIQIPSRQTAAGRVKME----------------KDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACPFLR-ERRGKSITTVLQPCSLFMEKCTWASGKQNINIVVKEFVIKISPIILNTVMTIMAAMSP-KTKEDEWKDTPKETDNLWAVKSITDYNSWFLGVDMATEVTENFRDSEHPSIE----------ENCVVAVESVQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAAADMTLEVHYYNETHAVWEPLIERVE-GNKPWSLKLNVKKNPIQDKSLMPGDDFI---PEPQTAVHISSGATMNITISKSCLNVFSNLAKGFSEGAASTFDYSLKDRAPFTVKNALGVPMKVQPNRNLKVMGSPEK----------------SDIYDVGAGQHLELDYASLEPSRQGKLSILSRQESSLFTLTFVPYGYTEVASVPVARPGRRLYNVRNPSASHSDSVLVQIDATEG-NKVVTLRSPLQIKNHFSIAFIIYK----FVKNVKLLERIGIARPEEEFHVPLDSYRCQLYVQPAGGLEQQYTHSSTYISWKEELHRSREVRCMLQCPAVEVSFLPLIVNTVALPDELSYIGAHG-EDWDPAYVIHLYPPLTLRNLLPYSLRYLLEGTAETHELAEGS-------------------------SADVLHS---------RISGEIIELVLVKYLGKNWNGHFRICDTLPEFFLVCFS------SDTAEVMTVDLSVHVRRIGCRMELSVFSPYWLINKTSRVLQYRSEE-------IHVKHPADFRDIILFSFKKKNIFSKNKVQLKISTSAWSNGFSLDTVGSYGCVKCPATNMEYLVGVSIKMS----SFNLSRVVTLTPFCTVANKSSLDLEVGEIASDGSIPTNKWHYVASSECIPFWPEN--LSGKLCVRVVGYEGSSKPFFYNRQDNGTLLSLEDLNGGILVDINTAEHSTVITFSDYHEGSAPALIMNHTQWDVLTYKQSGSQEELVLLPGETRLFAWADPTGIRKLTWNYAANFGEHDLLKDECGQFPYDANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADHEVALS---LHSLGLSLVNNENKQEVSYVGITSSGVVWEMK--PKQKWKPFSQKQIMSLEQAYSKRLASQ---DRGWVKLDSNFEVNFDKVPMEMRLPIRCPIKRDFLSGIQVEFKQSPHQRSLRARLYWLQVDNQLPGTMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKVDQGFLGAVISLFTPTTDPEAERKRTKLIQQDIDALNTELMESSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMIAIHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLMWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQG--PEEFAEGLVIGVRSLVGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEMGRQPKDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIIDMASSTFQGIQR----VAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLEN-HIKKLEGEAYQFHCAVPGNKRAVLMITNRRALFIKEVEILGHMSVDWQCLFEDFVCPPEVSENLLKISVKEQGLFHKKDSANIGHLRKIYLKDPITAKRAFDAIESAQSARQQQKLMRQSSVKLLRPQGPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZMR7-1", "uniprot_id": "A0A8I5ZMR7_RAT", "id": "A0A8I5ZMR7-1", "name": "", "aln": "MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAEKEEKSLQDIKQKELCRIEEALQKAAEKGAHG-EFMYGLESLLYKD--VKP----------------------DKPKEAKKDTFLEKLATQVIKNVQVKITDIHIKYEDDV-TDPERPLSFGVTLREFSLLTTNEHWTPCILNEAEKIIYKLVKLDSLSAYWNVGCCVSYRG-----SREHILDQLKCEILTSTNIPPDHQYIFQPISASAKLYMNPGAES---EFKTPKLDGNVEVQNIAIELTKPQYLSMIDFLESLDYMVRNAPYRKYRPC-LPLHTDCRQWWKYAIDSVLEVHIRRYTRPWSWNNIKNHRQLLKSYKMAYKNKLTQ-----TKVSEEIQKQIQDLEKSLDVFNIILVRQQAQVEVIHSGQKLRKKSSEAGEKRG--------WFSGFWGKKECKKRDEESSVPETIDDLMTPEEKDKLFTAIGYSENAYN---LALPKQYVAHILTLKLLSTSIVVRENR-----------NVPEILRIQIIGLGTQVSQRPG---------------AQALKIEAKLEHWYVTGLRQQDIVPSLVASIGDTTSSLLKIEFETNPENSPADQTLIVQSQPVEVIYDAKTINAVVEFFQSN--KGLDLEQITSATLMKLEEIKARTATGLTHIIETRKVLDLRINLKPSYLIIPQTGFHHE-KSNLLILDFGTFQLNSKDQGAQKTTNS----------SLEEIIDKAYDKFDVEIKSVQLLFA-KAGENWKKCRFQH-PSTMHILQPMDIHVELAKAMVEKDVRMARFKVSGGLPLMHVRISDQKIRDALCLINSIPLPQKSSTQ--SPE-RQVASIPVLSGGTKVL-LGTSLLLDGVESESDDEYFDAEDGDSQAARPVKASELRKAAEVPNEELVTLLLKFEIKEVVLELTKQQKEEETILVFNVTQLGTEATMRTFDLTAVSYLRKISLDYHEIKGSRKKPIHLVSSSDRPGLDLLKVEYIKVDRNGPSFQTTFEKTEQTVKVAFSSLNLLLQTQALLSSLNYLTTVIPSDSQNAGVAKEVQTITEKQ-KNSPLQKVMVPSRDSDVIGFRLFAKLNAFCVTVCDEKSNIAEIKIQGLDSSLSLQSKKQSLFARLENIIVTDVDPKTVHKKAVSIVGNEVFRFNLDLYPDATEGDSYTDMSTVDGVVALHVGCIQIVYLHKFLMSLLS------------FLNNFQVAKEALSAATAQAAEKAATSVKDLAQRSFRVSVDIDLKAPVIVIPQSSLSTNAVVVDLGLIRVHNQFSLVSGEDAVNPPVIDKMKVQLTKLKLCRTAIQSGVSHPDIQLLHPINLEFCVNRNLAANWYHKVPVVEIKGRLDSMNVSLNQEDLNLLFRILAENLGEATEDIDKGKPRIQEIGKTKACQDVSTPQDVHTTQGVPAARVEETRPVDIINVLLNFEIKEVVVTLMKKAEKKGNPLHELKILHLGMEAKVKAHDMTAKAYLRKITMRCFDFPDSKGEPLHIVNSSDVSDGTLLTMLFIKADSDGPDFQTIHDNTKQKLKVSFSSLDLVLHLEALLSLMDFLSCAVPSPDSSSSETESELKPLVGGSRSLAVKAVPS-SSEGDVFDLKVTAELNAFNIFICDQKSNIAEIKIHGMDASVSMKAKQTDVFARLKNIIVMNVD-----SLSIHKKAVSILGDEVFRFQMSLYPDATEGENYGDMSKVDGRLGLKVGCIQIVYVHKFFMSLLSFLNNFQAAKEALSTATVQAAERAASSVKDLAQKSFRLLMDIDLKAPVITIPQSSVSPNVVIADLGLIRVENKFSLVSVEQLSLPPVADKMSVQLTQLKLSRTVLQADSP------------QHDIEILKPVNMLLSIQRNLSAAWYTQIPGMEITGKLKPMQVALSQDDLTVLMKILLENLGEASSQPSPTQFAQEAARVKR---------DTRSGPDCLKEQ-DLAEPKPPGDQTVTLQFDFHFDSLSIVLYNSDGCQESRLSFHNDSFRLGELTLHLMASAGKMFKDGSMNVSLKLKTCTLDDLREGIERATSRMIDKKNDQDGNSS--------------MIDVSYSQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAMPESPEN-IAKDIQIPSRKTAPGRVKME----------------KDDSVKPNMTLKAMITDPEVVFVANLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACPFLR-ERRGKSVTTVLQPCSLFMEKCTWASGKQNINVMVKEFVIKISPIILNTVMTIMAALSP-KTKEEDQEDTAEEKDSLWAIKPITDYNSWFLGVDMATEATESFRDFEHTQIE----------ENCVVAVESVQVTLECGLGHRTVPLLLAESRFSGNIKNWTSLMAAAADMTLEVHYYNETHAVWEPLIERVE-GKTPWSLKLNVKKNPLQDKSLMPGDDFI---PEPHTAVHISSGSTMNITISKSCLNVFNNLAKGFSEGAASTFDYSLKDRAPFTVRNALGVPMKVQPNRNLRVMGSPEK----------------SDVYDVGAGQHLELEYASLEPSRQGKLSLLSRQESTFFTLTFVPHGYTEVASVPVARPGRRLYNVRNPSASRSDSVLVQIDATEG-NKVVTLRSPLQIKNHFSIAFIIYK----FVKNVKLLERIGIVKPEEEFHVPLDSYRCQLYVQPAGSLEQQYTQSTTYISWKEELHRSREVRCMLQCPAVEVNFLPLIVNTVALPDELSYIGAHG-EDWDPAYIIHLYPPLTLRNLLPYSIRYLLEGTAEAHELAEGS-------------------------SADVLHS---------RISGEIIELVLVKYLGKNWNGHFRICDTLPEFFLVCFS------SDTAEVLTVDLSVHVRRIGCRMELSVFSPYWLINKTSRVLQYRSEE-------IHVKHPADFRDIILFSFKKKNIFSKNKVQLKISTSAWSNGFSLDTVGSYGCVKCPATTMEYLVGVSIKMS----SFNLSRIVTLTPFCTVANKSSLELEVGEIASDGSIPTNKWHYIASSECIPFWPEN--LSGKLCVRVVGYEGSSKPFFYNRQDNGTLLSLEDLNGGILVDINTAEHSTVITFSDYHEGSAPALIMNHTQWNVLTYKQSGSQEALVLLPGETRLFAWADPTGTRKLTWSYAANFGEHDLLKDECGQFPYDANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADLEVALS---LHSLGLSLVNNENKQEVSYVGVTSSGVVWEMK--PKQKWKPFSQKQIMLLEQSYQKHLTSQ---DRGWIKLDSNFEVNFDKVPMEMRLPLRCPIKRDFLSGIQVEFKQSPHQRSLRARLYWLQVDNQLPGTMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKVDQGFLGAVIALFTPTSDPEAERKRTKLIQQDIDALNTELLESSMSDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMIAIHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLMWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQG--PEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEMGRQPKDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIIDMASSTFQGIQR----VAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLEN-QIKKLEGEAYQFHCTVPGNKRAVLMITNRRVLFIKEVEILGHMSVDWQCLFEDFLCPPGVSENLLKISVKEQGLFHKKDSANVGYLRKIYLKDPITAKRAFEAIESAQSARQQQRLMRQSSVKQ-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q709C8-1", "uniprot_id": "VP13C_HUMAN", "id": "Q709C8-1", "name": "Intermembrane lipid transfer protein VPS13C", "aln": "MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKD--IKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDV-TDPKRPLSFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQR-----SREQILDQLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAES---ELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKYKPY-LPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQ-----SKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGG-------WFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHN---LTLPKQYVAHIMTLKLVSTSVTIRENK-----------NIPEILKIQIIGLGTQVSQRPG---------------AQALKVEAKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSN--KGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHE-KSDLLILDFGTFQLNSKDQGLQKTTNS----------SLEEIMDKAYDKFDVEIKNVQLLFA-RAEETWKKCRFQH-PSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQ--SPE-RQVSSIPIISGGTKGL-LGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLN------------FLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVD-----LQSIHKKAVSILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLP------------QNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKV--------DVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSS--------------MIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPEN-VAKETQILPRQTATGKVKIE----------------KDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACPFLR-EKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALSP-KTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIE----------ENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLIERVE-GKRQWNLRLDVKKNPVQDKSLLPGDDFI---PEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEK----------------SDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEG-NKVITLRSPLQIKNHFSIAFIIYK----FVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHG-EDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGS-------------------------TADVLHS---------RISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFS------SDSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSED-------IHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMS----SFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPES--LSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLS---LHSLGLSLVNNESKQEVSYIGITSSGVVWEVK--PKQKWKPFSQKQIILLEQSYQKHQISR---DHGWIKLDNNFEVNFDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQG--PEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQR----AAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLEN-HIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVEILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGCVRKVYLKDTATAERACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P9K9-1", "uniprot_id": "A0A8M9P9K9_DANRE", "id": "A0A8M9P9K9-1", "name": "", "aln": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRS-KKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDV-SDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKD-----SWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEV---ELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPD-VPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQS----AKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGG------FFSSFFGKKEGKK-EEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHN---LALPKHYVAVIVNFKLLSTSVTFREEP-----------GVPEILKVQMIDLSTSISQRPG---------------AQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTG--KGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDG-KSELMIVDFGYLQLNSVDQGGHQQVSASF-------SSLEEIMDRAYERYSLELRSVQILYS-RSGEKWKSACHEG-LSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESD---------EDTSEKSVDEESLR----STLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIP---QELTANKERETRRRAD-RAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEG--TKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERES-RKSEDMKTTSAKSTALSS-PSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVD-----SKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSD------------QTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRA---------RTATGSEILEEKLSESKLKET-ELLESVRFSFNVESLGLTLYNNDPSQP---CVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRR-DEETSEP--------------MIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEP-----------KAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIR-AEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAP-KPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDG----------ETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIM-LPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTL----------------GKVHELAVDKSLDLEYSSFERSS--RQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEG-NKVITVRSPLQIKNHFSVPFAILK----YSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGS-------------------------AADVLNS---------NVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFN------CDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAED-------TFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMS----SFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGS-SNKWHYISSTECLPFWPES--STEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQY-GGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVS---LQNLGLSLINNDIRQEIAYVGITSSGVVWEMR--PKNRWKSFNHKNIGLLEKAYQNHINKS---DPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDES--EQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQG--PEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z713-1", "uniprot_id": "VPS13_DROME", "id": "A1Z713-1", "name": "Intermembrane lipid transfer protein Vps13", "aln": "MVFEAVVADVLNKVLGDYIENLDRNQLKIGIWGGDVVLQNLKIRENALDELDLPVQLIYGYLGKLVLKIPWKNLYSQPVIVNIEDLYVLVSPNNNVQYNAEKEAKYEMDLKKAALDALEAARKKELEMDQPK-----------------------------------------------ADAGFAEKLTAQIVNNLQVQITNVHLRYEDTT-TTG-SPFSFGISLHELELYTTDCDWEKCYMAQQASQVFKIANLSCLSAYLNCGGQLYANN-----KSD--LSQQFKTNIACKETKPNYNYVLGPISCNAKLKLNMNPELDDPPFEKPKIDLTLEMEKLNVGLTNTQFDNLMKLGDAMNRQQLGIPYRKYRPYNIPYKGHARDWWHFAITSILEEEVRKPRESWTWGHIKTHRERCNTYAQKYKEQCLS-----KKPSAVLTETCRLLETELDVFNLLLIRQRVNIEIAKQREAVPEQKSGWFSGWG------------WGGGAKKDDQTTSQKLVEKFEAAMTSEEKEKMYRAIGYQENAKP---TDLPESYEAIRMNFKLIALEVGLYKDERNSSAATKDFHELPSLVLLNFSMATALITQRPA---------------AEAISIIAGMREIKVTGLTRNDYTPLLVESKITDEFNLLEVFFETNPLDKLCDQRVKVVARPLQITYDAPTILALINAFQTP--GDVTLSKFEDAASTKISNFKERSATGMQYMIDKKAVLDVDILLMPNILVVPHKGVYDAGNVSLLVVSMGQVHLSSQPRRESNKLQHLFSAGEDKDEILKTVMENAYDRFTVAVDDVQMLVV-RAGEPWQNALAEANSTEMHVLRPVSLKVTAALCVVDNDPRLPNIKVDIDLPAILVNVSEDRIFLAIKVATSIPLPEQ-------------------------------------------------------------------------------------------------------------------------------------------KEPASRLTQTNSRSSMSISNFINKEVKKIGP--------------------------------------------------------------------------------------------------------------SASGSSASKDPLLDEIIQYTSLDVN---------FSLGEINFVLFQSSRKCETSPDVSIEFLTPDGDVLP-----------------------------------------------SQLTENIQEPIEELPPTPPQQILSIDIRR-------------------------------------------------------------------------------LEAHFVSKTYESVATVKLG-DINLRQYDCQDSDMDVLDVIYTPKQENSSNYLFTVSCTIADKSSPEFSTKYNSTEQLVVAN------------FEVLQIVLHQECLQRIMEVVNNFQRN------------------------------------LDLVLSSTRPRDRMGSIGGGDGIKRTLNVILEDT----------------------------------------------------------EEIMTTDQMKRRKKTRRTHVVETVKVRVIANLDQVGLVLTGRKRPIAEMNVKKFVSSLIIKSSYTEVNIGLKDIQVLDLN-----PYTIHKNILSIVGKDAFNCQIVIYNKEE----TQDYNSDDMKITVDIGCMKIIFLNWFVAGVMNFLNNFTAAQATISQAGAAAAESARQKAMDAYETATRMKLNIRIKAPIIIVPIGSQDRNALLLDLGLLELTNNTVEVAVAEEERLAVIDEIKLQICDVKISKIVLLDGNESTVDEVDAEVGFLSKFNMMNPMSCTLSITRNLSYTWYRDVPELNLSGRLKSIELTLFADDYALVMLVLNRNLNEGLEEFPPSEEAPQEAQVRPE--------RRNSRAGRLSRTVQVSP--IREKIHESIKFNFQFDGVVINLMEG------------EGAGLARFGIYFLSVKGTKLDNGTLSTSVVLCNIQMDDMRSNSKSQIRQYLSRKDWVQPKLDTDEIIDACYNERNFMVDVTAIIKEDDTFAEVRVRGFDLIVCIDFLLKLTTFLTLPPEENPRESVYIKPAPVSETARDTKHSIRSSAILAAQELVPVESSSHEVPNRKMNLILHIDEPDIILVENLEDLNTSCIIFNAQVHLNYRSINDKQIVNGQIDALKMYMCAFLP-ERREMTRHYILHPCVISLQGSTPEEEGMHISLKLSDIIINVSPATIELLNKAMLSVSSGTMTKCAIAEESRNYSNLWHQHHFHSRTYWFTKVEQGVDALEAEQRSVSTDNEKQK------TEKCVIEIPSITLVIESGVGYYTKPLISLDTRITAVFNNWSRSLTAHGSLTLNMNYYNQALAEWEPIIELNEVIGRNGVREYTPWELKFEMGMEKVQSELEDDAEQQAMHMNIHSAETLEITLSKTCLGLLSELAEAFSQAIDQNGLTKPDIVAPYVLENDTGFDVNLNLRKGIFTLHEVHRGGTPVGANSTLLMVAQSEEVDPSVIKTCTISTGGRAYLQTKDLSTLSEEDSEDYTLYVTIGDINKEIALPVSKSDTRFFNLMRSTSHEPWGIISEVKQEYG-TTKVNIHGVVSVHNHFTTGLNIYRRNPAPTAQCFEDIFVGRVRPGEVFHVPLHAIYAESKDLFFS--MRGYRRSVQGISWASNPS-DLNYSHQLHCDPTNT-FEPLIMNARRSKSEVYFENTNKYTLLSAFYTIHLRPPLYLRNSLPINIQVSVAGCSVRKEDGLDAQSSQRFVDRGYRKEDFLDYGEKPVNSGDVLHLPTVRLASKGKESKSFLVVRLVQYLEKDWSCATEIWDYTDDVITWTFSS-----YDSEMKVDMDLYVKTENRHGSLMLTLFSPFWMINKTGMMLTYKSETT----SVEVLYHPPEYSGPILFTFRDKLFFDKKKASIRIDNGQWSEKIPLDVAGSVGEVICFANNQKYPVGVHNHLT----QNSLTKQITFIPFYIVCNKCHFDIELQEQ----SRPADPWLHLEPNEMEPLWPRN--DTKNNLVVRVDG-KITPAFDFTEVICTLLKLEDSKYGGINVDVQTTEGGVYITFTDYKPADAPGLLINHTG-KQIVYHEKGTKNEHILNAKSTIMYAWDDPTGPKMLVFGTNK--EETDLKRDGIGEVIMQDGGKVLWVSFLDGLQRVLLFTENESIANRTESTASLQSITQSIDLR---IHGIGLSVINNETGLDILYLGVTSSGIIWESKKVTKNRFKELTINENALLEIEYQKYLVHKSVNDVQTYKLDNKFPIDFD--LMILKKTVERNLRRSFYPAIWLSRKSSPFQSQLHVKINRIQVDNQFLDPIFPVVLAPIPPPKSVASTTSLKPFIECSMVQRIMPNSTVRQFKYARILIQEFLFKVDLNFLTAIAEMFAKEVSDEAAAKQFRQDVESIELPLSAFFEEHSLEE-QKSFYDNLHLGPLKIHVSFSMAG--------SDTKALPGFLGSLVQGVGVTLTDVNDVVFRLAFFEREYQFFSQKQLINEITSHYTGQALKQLYVLVLGLDVLGNPYGLVVGLKKGVEDLFYEPFQGAIQG--PGEFAEGLVLGVKSLFGHTVGGAAGAVSKITGAMGKGLAALTFDEDYQKKRRQGIQNKPKNFHEGLARSSKGLVMGFVDGVTGVVTKPVTGARDNGVEGFFKGLGKGAIGLVARPTAGVVDFASGSFEAVKR----AADASEDVKRMRPPRFQHYDFVLRPYCLMEATGNKIMKETDKGKFATTDNFIHCEEIIQKSEYLVVTNYRVMYVQRNEMFGVWTSLWSYLWNEISSVAATARGVQFTVKTDGKKVLGLFSSKESPRKLVLVADERKRDALVDIIESQRSDPNPLRATIAYPAHN-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07878-1", "uniprot_id": "VPS13_YEAST", "id": "Q07878-1", "name": "Intermembrane lipid transfer protein VPS13", "aln": "-MLESLAANLLNRLLGSYVENFDPNQLNVGIWSGDVKLKNLKLRKDCLDSLNLPIDVKSGILGDLVLTVPWSSLKNKPVKIIIEDCYLLCSPRSEDHENDEEMIKRAFRLKMRKVSEWELTNQARILSTQSE-------------------------------------NKTSSSSSEKNNAGFMQSLTTKIIDNLQVTIKNIHLRYEDMDGIFTTGPSSVGLTLNELSAVSTDSNWAPSFIDITQNITHKLLTLNSLCLYWNTDSPPLISDDDQDRSLENFVRGFKDMIASKNSTAPKHQYILKPVSGLGKLSINKLGSTE----EQPHIDLQMFYDEFGLELDDTEYNDILHVLSSIQLRQITKKFKKARPS-FAVSENPTEWFKYIAACVINEIHEK-NKMWTWESMKEKCEQRRLYTKLWVEKLKLKNLEAPLRDPIQEAQLSELHKDLTYDEIILFRSVAKRQYAQYKLGMTEDSPTPTASSNIEPQTSNKSATKNNGSWLSSWWNGKPTEEVDEDLIMTEEQRQELYDAIEFDENEDKGPVLQVPRERVELRVTSLLKKGSFTIRKKK-----------QNLNLGSIIFENCKVDFAQRPDSFLSSFQLNKFSLEDGSPNALYKHIISVRNSSKDQSSIDNHATGEEEEEDEPLLRASFELNPLDGLADSNLNIKLLGMTVFYHVHFITEVHKFFKASNQHMETIGNIVNAAEATVEGWTTQTRMGIESLLEDHKTVNVSLDLQAPLIILPLDPHDWDTPCAIIDAGHMSILSDLVPKEKIKEIKELSPE-EYDKIDGNEINRLMFDRFQILSQDTQIFVGPDIQSTIGKINTASSTNDFRILDKMKLELTVDLSILPKAYKLPTIRVFGHLPRLSLSINDIQYKTIMNLIANS----------------------------------------------------------------------------------------------------------------------------------------------------IPSMIDDEENNGDYVNYSSGSEK-----------------------------------------------------------------------------------------------------------------EMKKQIQLQLKNTLKALENMQPLQIEQKFLELH--FDIDQAKIAFFQCIKNDSRNSEKLVDILCQR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------LNFNFDKRAKEMNLDLRVHSLDVEDYIELTDNKEFKNLISSGVEKVTRSQKDLFTLKYKRVQRIVPHN-------------DTLIELFDQDIVMHMSELQLVLTPR-------------------------------------SVLTLMNYAMLTFTDPNAPEMPADVLRHNKEDR-----------------------------------------------------------------------------DDAPQKINMKIKMEAVNVIFNDDSIKLATLVLSAGEFTMVLLPERYNINLKLGGLELTDETNESFSRDSVFRKIIQMKGQELVELSYESFDPAT------NTKDYDSFLKYSTGSMHVNFIESAVNRMVNFFAKFQKSKVSFDRARLAAYNQAPS-----IDAVNNMKMDIVIKAPIIQFP-KLVGTQENNYDTMRFYLGEFFIENKFSVIDESHKINHIKLGVREGQLSSNLNFDGSS-------------QQLYLVENIGLLFNIDR--DPLPQDDTPELKVTSNFESFALDLTENQLTYLLEISNKVSSAFNITDENSGESGGKGEIKSPSPDPASLSSESERTATPQSLQGSNKSNIKNPEQKYLDFSFKAPKIALTLYNKTKGVTS-----LNDCGLTRIMFQDIGCSLGLKNDGTVDGQAHVAAFRIEDVRNIKDNKHTELIPKSKNKEYQFVAN-------------ISRKNLEVGRLLNISMTMDSPKMILAMDYLVSLKEFFDAIMSKSHENNLYYPENTNQKPENKAIVESVQ----------------EGGDVTKIQYSVNIIETALILLADPCDMNSEAISFKIGQFLVTDQN----IMTVAANNVGIFLFKMNSSEEKLRLLDDFSSSLTIDKRNSTPQTLMTNIQLSVQPLLMRISLRDIRLAMLIFKRVTTLLNKMTEKEDNGEEEESTDKIQFSHEFERKLAVLDPSILGERSRASQSSDSESIEVPTAILKNETFNADLGGLRFILIGDVHEMPILDMNVN-EITASAKDWSTDFEALASLETYVNIFNYSRSSWEPLLEMIP-------ITFHLSKGHSEMD--------------PAFSFDILTQRIAEITLSARSIAMLSHIPASLTEELPLASRVSQK---PYQLVNDTELDFDVWIQDKTTE----------------------DNKNEVVLLKANTSLPWEFEDWRSIREKLDIDKSKNILGVCVSGQNYKTIMNIDATTEGENLHVLSPPRNNVHNRIVCEARCDENNVKIITFRSTLVIENTTSTEIELLVD----SKDPNKPSLKYAIKPHQSKSVPVEYAYDS-DIRIRPASEDIYDWSQQTLSWKSLLSNQMSIFCSSKEDSNQR---------FHFEIGAKYDEREPLAKIFPHMKIVVSASMTIENLLPADINFSIFDKREEKRTDFLK-------------------------TGESMEVH--------HISLDSFLLMSVQPLQDEASASKPSIVNTPHKSPLNPEDSLSLTLSGGQNLLLKLDYKNIDGTRSKVIRIYSPYIIMNSTDRELYIQSSLLNIAQSKILLENEKRYTIPKMFSFDKEDDKS-NRARIRFKESEWSSKLSFDAIGQSFDASVRIKNKEQESNLGINISEGKGKYLLSKVIEIAPRYIISNTLDIPIEVCETG------SMDVQQIESNITKPLYRMRNIVDKQLVLKFLGGDSNWSQPFFIKNVGVTYLKVLKNSRHKLLKIEILLDKATIFIRIKDGGDRWPFSIRNFSDHDFIFYQR-------------------DPRKVSDPYKDDQSNESSSRSFKPIFYRIPSKSIMPYAWDFPTAKEKYLVLESGTRTREVRLAEIGELPPLRLDKRSKDKPAPIVGLHVVADDDMQALVIVNYKANVGLYKLK--TASATTTSSVSVNSSVTDGFVQKDEDE--------KVNTQIVVSFKGVGISLINGRLQELLYINMRGIELRYNESKAYQTFSWKMKWMQIDNQLFSGNYSNILYPTEIP-YTEKEIENHPVISGSISKVNDSLQAVPYFKHVTLLIQEFSIQLDEDMLYAMMDFIKFPGSPWIMDSRDYKYDEEIQLP-----DVSELKTAGDIYFEIFHIQPTVLHLSFIRSDEISPG-LAEETEESFSSSLYYVHMFAMTLGNINEAPVKVNSLFMDNVRVPLPILMDHIERHYTTQFVYQIHKILGSADCFGNPVGLFNTISSGVWDLFYEPYQGYMMNDRPQEIGIHLAKGGLSFAKKTVFGLSDSMSKFTGSMAKGLS-VTQDLEFQRVRR-LQQRINKNNRNALANSAQSFASTLGSGLSGIALDPYKAMQKEGAAGFLKGLGKGIVGLPTKTAIGFLDLTSNLSQGVKS--TTTVLDMQKGCRVRLPRYVDHDQIIKPYDLREAQGQYWLKTVNGGVFMNDEYLSHVILPGKELAVIVSMQHIAEVQMATQEL-----MWSTGYPSIQGITLERSGLQIKLKSQSEYFIP-------------ISDPEERRSLYRNIAIAVREYNKYCEAIL------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*::.:::**:.:*.*:**:: .**::***.*:* *.**:::::.*..*::*..: * :..*.*.:**..* .:.* ::. *:* * : : : : * : * : : . * :.*:::::.*:** *..:*::*** * :.*::* *:. ::: .* . : . .*: *..:. * * . . : : : . ::*:: *: .:: :* . : *: : : ::: : : ..:: .::.. .::: ::* :* .. . *::: .::: .: . *.* :* : : . * : : *.. * :::* *. .: : : : ... . * . . : ** *::.::: ** :. . :*. :. * .. . :. .: : : . .:*** ... : : :. :.. . ** ** ** : .*. : : : : *.. : : : *:: : : .*: .:. . :: *: ::: : .::: : * . :::* :: . . . : : . : : :::: : ..*:: . . . ::* :.: : .:: : ::. ::* ** : : :.: : : : . ... . . : . . . : : : ::: :.: : : . : : .:. : . .:.: * . : .: . . : : : : ::. : : : . . . : * .: : :: ..:.. . . :* : : :: : .: * .: : : ::.:: :.: *.: . . : .. * : . *.::: ::. . ::.* :* :: ::. * * : * . : .: ::* :***:* .* . : * : : : . :.:.: : : ::: . . ::: :. : : * . . ::: . ::.: : * :: : :: : . . : :: . . : *.*: : : * : : * .: : : .:*.:. . : ::* *. . . : : : . :. . : : .:::*: : *: . . . : :. :::: . . :: .: . : : : : : . . . : . .: :. .::.:* :. ::. . : : .. . : :: . . *. : : . : .: . : : :: ::*: : . ..: :: :* : ***::* : . . * : :**:* .: ::..:. .::: . . *: : * . . : .. : : . :.. : . . . : . .:. : . :: : . . :..:. : :.* : : : : .* : **:. . * * ::* . . . : . : . . * : ..: :.* ** .:. : . . :.: :. . * . : : :: : . . . . :.: : : :.**: ::*.* * ::. : : : :*:* .: :: : .. . **. :.:*. *. . .. . .: ::: . *:: : : * : *. : :*: * : : .. *:: : : :. : . . :.:: . * : . : :.: . : : ** . : .. . * : ::: : : . .: . :** :: :: : :. .:. ::: : . . . . . : : : ::. : :.* : : : .* : :.* : :: :*:***: . :. :: * * . :*.*. *: . * **: *:**: .::* .:* *: :: . : :.:: : . ::: :*: * :*:*: .. . :: .. ** :::: .:: *: : **: * : *:: :: . * :*** **. :..** :**** ** : . * *:. *. * *: :** * :. :*::**::.***: :* * ::*: ** . :: :.**...:.: . .*::*: .* . :.:*. **:**:*** :* ::.: *.:*::*. :.:: .. :. :* * . * :::** : * :: . : * . :: : . : : *. : .: . . : . : . * : ", "identical_positions": 265, "similar_positions": 972, "identity": "6.63%" }, { "cls_id": "homologset.agr.MGI:2444209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q566C8-1", "uniprot_id": "ANR54_RAT", "id": "Q566C8-1", "name": "Ankyrin repeat domain-containing protein 54", "aln": "MAATGGGAEDESRSG-RSSSEGECAVAPEPLAEAGGLFSFADLGAALGSG-AGLPG------------RAVGRAQSPLRYLQVLWQQD--VEPRDELRCKIPAGRLRRAARPHRRLGPTGKEVH-------------------------------------------ALKRLRDSANANDIETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPNQQDGLGNTPLHLAACTNHVP----VITTLLRGGARVDALDRAGRTPLHLAKSKLNILQEGHSQCLEAVRLEVKQIIHMLREYLERLGRHE-QRERLDDLCTRLQMTSTKEQVDEVTDLLASFTSLSLQMQSMEKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WK7-1", "uniprot_id": "ANR54_MOUSE", "id": "Q91WK7-1", "name": "Ankyrin repeat domain-containing protein 54", "aln": "MAATGGGADDESRSG-RSSSDGECAVAPEPLAEAGGLVSFADFGVSLGSG-AGLPG------------RSVGRAQSSLRYLQVLWQQD--VEPRDELRCKIPAGRLRRAARPHRRLGPTGKEVH-------------------------------------------ALKRLRDSANANDVETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPNQQDGLGNTPLHLAACTNHVP----VITTLLRGGARVDALDRAGRTPLHLAKSKLNILQEGHSQCLEAVRLEVKQIIHMLREYLERLGRHE-QRERLDDLCTRLQMTSTKEQVDEVTDLLASFTSLSLQMQSMEKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NXT1-1", "uniprot_id": "ANR54_HUMAN", "id": "Q6NXT1-1", "name": "Ankyrin repeat domain-containing protein 54", "aln": "MAAAAGDADDEPRSG-HSSSEGECAVAPEPLTDAEGLFSFADFGSALGGGGAGLSG------------RASGGAQSPLRYLHVLWQQD--AEPRDELRCKIPAGRLRRAARPHRRLGPTGKEVH-------------------------------------------ALKRLRDSANANDVETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPNQRDGLGNTPLHLAACTNHVP----VITTLLRGGARVDALDRAGRTPLHLAKSKLNILQEGHAQCLEAVRLEVKQIIHMLREYLERLGQHE-QRERLDDLCTRLQMTSTKEQVDEVTDLLASFTSLSLQMQSMEKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DGX3-1", "uniprot_id": "ANR54_DANRE", "id": "Q6DGX3-1", "name": "Ankyrin repeat domain-containing protein 54", "aln": "MDGSSPLLAAAGSDGDRSSSEGEYTLAGGPSAGDTEKREGESPMEAAGAGTVGFSISRLDTLSALRLNRTRPAADTELRYLHLLWKPGELLQAGRSTPGKITSSRVRRLARARRNMGPIGKDLH-------------------------------------------AVKRLREAANSNDIDTVRRLLEDDTDPCAADDKGRTALHFSSCNGNETIVQLLLSYGADPNQRDSLGNTPLHLAACTNHVP----VITTLLRGGARVDALDRAGRTPLHLARSKLNILQEGDSRSLETLRGEVTQIIQMLREYLNIMGQSE-EREKLEHISTQLQNTRTREQVDEVTDLLASFTSLSIQMQNMGDR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VT59-1", "uniprot_id": "Q9VT59_DROME", "id": "Q9VT59-1", "name": "Ankyrin repeat domain-containing protein 54", "aln": "---MAAATNNDSSGVESAKEEVEMSMPPSPMSMAMVLAKSTPMPMPTSASKGIMITP--PPPAMPPTPTSSPNTHGEWPHMNINLNLNMSSNPSTNASFQLSRDRGEHFALPHLPPLPLNPNASNAEYLPSLIHPSTLPSGSKSFKMRPRMQRLKHSYSYSNIIVQSNGRKLRTAASTCNIELLNRILEGGANPNAADEYNRSPLHLAACRGYIPIVQQLLKYGANPNVVDSLGNTPLHLAVISASSNNFNVVVGVLLQGGASVHMYDRSNKSPLELAEAKLRLLRNRYDHPTPETAKILEDMCMLTTLILRYMVKQQRELEDLSALEKRLQNLSTSDDQEQVVSQTADELLASVERLSINNK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :..: * ::. * : . . ... : : :. :::: : . :. . ::. .* .: * .: * . : ::** :*.: ::: :.::**..::* ***: .*:.**:::*.* *** **.:**:** *.*********. : *: .**:*** *. **:.::**.**.:**.:*:: : : :: : *. : : : : * *. : .:** * :: ::*.. *. *:: .: .:", "identical_positions": 63, "similar_positions": 110, "identity": "17.36%" }, { "cls_id": "homologset.agr.MGI:2444210", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63503-1", "uniprot_id": "NR1D1_RAT", "id": "Q63503-1", "name": "Nuclear receptor subfamily 1 group D member 1", "aln": "----------------------------------------------------------------------------------------------------------MTTLDSNNNTGGVITYIGSS--GSSPSRTSP-----------------------------------------------------------------------------------------------------------------ESLYSDSSNGSFQSLTQGCP-TYFPPSPTGSLTQDPARSFGTVPPSLSDDSS---------------------------------------------PSSASSSSSSSSSSFYNGS-------------------------------------------PPGSLQVAMEDSSRVSPSKGTSNIT---------------KLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQNAMN-----------------LANNQLS-----------SLCPLETSPAPHPTSGS-------VGPSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPAPAPT-PLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHDKLGTSPGNFNANHASGSPPATTPQCWESQGCPSTPNDNNLLAAQRHNEALNG------------------------LRQGPSSYPPTWPSGPAHHSCHQPNSNGHRLCPTHVYSAPEGKAPANGLRQG------NTKNVLLACPMNMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFAS-------LFNVKDQTVMFLSRTTYSLQELGAMGMGDLLNAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQKTLLR-------------ALRALVLKNRPSETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVDAQ------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UV55-1", "uniprot_id": "NR1D1_MOUSE", "id": "Q3UV55-1", "name": "Nuclear receptor subfamily 1 group D member 1", "aln": "----------------------------------------------------------------------------------------------------------MTTLDSNNNTGGVITYIGSS--GSSPSRTSP-----------------------------------------------------------------------------------------------------------------ESLYSDSSNGSFQSLTQGCP-TYFPPSPTGSLTQDPARSFGSAPPSLSDDSS---------------------------------------------PSSASSSSSSSSSSFYNGS-------------------------------------------PPGSLQVAMEDSSRVSPSKGTSNIT---------------KLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMN-----------------LANNQLS-----------SLCPLETSPTPHPTSGS-------MGPSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPAPAPT-PLVGFSQFPQQLTPPRSPSPEPTMEDVISQVARAHREIFTYAHDKLGTSPGNFNANHASGSPSATTPHRWESQGCPSAPNDNNLLAAQRHNEALNG------------------------LRQGPSSYPPTWPSGPTHHSCHQPNSNGHRLCPTHVYSAPEGEAPANSLRQG------NTKNVLLACPMNMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFAS-------LFNVKDQTVMFLSRTTYSLQELGAMGMGDLLNAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQETLLR-------------ALRALVLKNRPSETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVDAQ------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P20393-1", "uniprot_id": "NR1D1_HUMAN", "id": "P20393-1", "name": "Nuclear receptor subfamily 1 group D member 1", "aln": "----------------------------------------------------------------------------------------------------------MTTLDSNNNTGGVITYIGSS--GSSPSRTSP-----------------------------------------------------------------------------------------------------------------ESLYSDNSNGSFQSLTQGCP-TYFPPSPTGSLTQDPARSFGSIPPSLSDDGS---------------------------------------------PSSSSSSSSSSSS-FYNGS-------------------------------------------PPGSLQVAMEDSSRVSPSKSTSNIT---------------KLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMN-----------------LANNQLS-----------SQCPLETSPTQHPTPGP-------MGPSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPAPVPS-PLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNG------------------------LRQAPSSYPPTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEGKAPANSPRQG------NSKNVLLACPMNMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFAS-------LFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQETLLR-------------ALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVDAQ------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RAU6-1", "uniprot_id": "F1RAU6_DANRE", "id": "F1RAU6-1", "name": "Nuclear receptor subfamily 1 group D member 1", "aln": "---------------------------------------------------------------------------------------------------MTLLGLNMTTAVDTNNTGGVISYIGSC--GGSPNRTSP-----------------------------------------------------------------------------------------------------------------VSMYSENSNSSMQSLTQPCFGSSFPPSPNG--SHDSSR--------MYTSSS---------------------------------------------SSSSSGSGEDGNSSCSGGS-------------------------------------------PRG---RDDGGSARNSPNKSVATLT---------------KLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNETCTIMRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQNAMNN----------------MVNNQLQNEFQLASITSNTPCPSSSSPSNTSSSSSSPCPGLTVGPQPQPPAV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVAQSPSSPAPTSPTVQLAQSPPPLTSTPPPCTSPGVDKTIAAITRAHRETFIYAHDKLGSPLLPHNSELDNRSNNRCMAG-YHLNGHNTIYHHDNNVAHHCNNFEVQ------------------------------QDNSLHFQASQTPEKHQQHNNNSQRPPNSNFYSIHHG-QEMNSASQGQNCPWKKHKEILLACPMNMHPYSDPNKTPQEIWEDFSLSFTPAVREVVEFAKHIPGFSTLSQNDQVTLLKAGTFEVLMVRFSS-------LFNVKEKTVTFISGATYSLEALKSMGMGDLLGTMFDFSEKLNSLELSAEELGLFTAVVLVSADRSGIENVNSVEMLQESLIR-------------ALRTLVSKSAPTDASRFTKLLLKLPDLRTLNNMHSEKLLSFRIDA-------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P13055-2", "uniprot_id": "E75BB_DROME", "id": "P13055-2", "name": "Ecdysone-induced protein 75B, isoform B", "aln": "MEAVQAAAAATSSGGSSGSVPGSGSGSASKLIKTEPIDFEMLHLEENERQQDIEREPSSSNSNSNSNSLTPQRYTHVQVQTVPPRQPTGLTTPGGTQKVILTPRVEYVQQRATSSTGGGMKHVYSQQQGTAASRSAPPETTALLTTTSGTPQIIITRTLPSNQHLSRRHSASPSALHHYQQQQPQRQQSPPPLHHQQQQQQQHVRVIRDGRLYDEATVVVAARRHSVSPPPLHHHSRSAPVSPVIARRGGAAAYMDQQYQQRQTPPLAPPPPPPPPPPPPPPPQQQQQQYISTGVPPPTAAARKFVVSTSTRHVNVIASNHFQQQQQQHQAQQHQQQHQQHQQHQQHVIASVSSSSSSSAIGSGGSSSSHIFRTPVVSSSSSSNMHHQQQQQQQQSSLGNSVMRPPPPPPPPKVKHASSSSSGNSSSSNTNNSSSSSNGEEPSSSIPDLEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQSTQNRGQQRALATELDDQPRLLAAVLRAHLETCEFTKEKVSAMRQRARDCPSYSMPTLLACPLNPAPELQSEQEFSQRFAHVIRGVIDFAGMIPGFQLLTQDDKFTLLKAGLFDALFVRLICMFDSSINSIICLNGQVMRRDAIQNGANARFLVDSTFNFAERMNSMNLTDAEIGLFCAIVLITPDRPGLRNLELIEKMYSRLKGCLQYIVAQNRPDQPEFLAKLLETMPDLRTLSTLHTEKLVVFRTEHKELLRQQMWSMEDGNNSDGQQNKSPSGSWADAMDVEAAKSPLGSVSSTESADLDYGSPSSSQPQGVSLPSPPQQQPSALASSAPLLAATLSGGCPLRNRANSGSSGDSGAAEMDIVGSHAHLTQNGLTITPIVRHQQQQQQQQQIGILNNAHSRNLNGGHAMCQQQQQHPQLHHHLTAGAARYRKLDSPTDSGIESGNEKNECKAVSSGGSSSCSSPRSSVDDALDCSDAAANHNQVVQHPQLSVVSVSPVRSPQPSTSSHLKRQIVEDMPVLKR-VLQAPPLYDTNSLMDEAYKPHKKFRALRHREFETAEADASSSTSGSNSLSAGSPRQSPVPNSVATPPPSAASAAAGNPAQSQLHMHLTRSSPKASMASSHSVLAKSLMAEPRMTPEQMKRSDIIQNYLKRENSTAASSTTNGVGNRSPSSSSTPPPSAVQNQQRWGSSSVITTTCQQRQQSVSPHSNGSSSSSSSSSSSSSSSSSTSSNCSSSSASSCQYFQSPHSTSNGTSAPASSSSGSNSATPLLELQVDIADSAQPLNLSKKSPTPPPSKLHALVAAANAVQRYPTLSADVTVTASNGGPPSAAASPAPSSSPPASVGSPNPGLSAAVHKVMLEA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ...*** :.:: * * :..*::* : * :.. . *: . . **.* .:: : .: :: .*.....: .** * .*: *..... . : :::* .:**:**** *********:**************:***: * **: *:*:******** **:***::************:***** *:** **.: : : * . .. . .: . :.* * :* .: * * .. ... * : .:: :.. : .. *:. .. : : :.: : : :. :: . .. .. : .... : : .. :. : .:: ..*:. . ..: ::* **:.: .:: : .: . :.:. *: **. . :* * . : . . .: . : . *: : :.: . .* : . . * *:: * *: : :*: * * . *: .. * :: .: ..: * . : :: :* : :. ", "identical_positions": 121, "similar_positions": 202, "identity": "8.56%" }, { "cls_id": "homologset.agr.MGI:2444211", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZP67-1", "uniprot_id": "D3ZP67_RAT", "id": "D3ZP67-1", "name": "", "aln": "-METGTHRARKRPTSRMGSWFRLPFL-RRSHACTSEFPKPSSRPNLEV-----SARPEPRTRYWTKLLSQLLALLPSLLQKLLIWSQLFGGMIPTRWLDFSASYSALRALR-GREESAAPTVQKSLNSLRLDSSSEDLVVSSLDWLEEGLQGQCSSSDLELKFKAQERALDSTAHTFLLEQQLWGVELLPGSLQTGLVSHRELGSSSSGPLSTQSLGNFKVVSYLLNPSYLDCLPQLELRCQNSVGGGQLVDFRTLSPESCYLSEDACHPQPLCAEMSATAWRRCPPLSTEGLPEIHHLRMKRLEFLQ-ANKGQELPTPDQDNGYHSLEEEHCLLRMDPQHCTDKAAQAVSPAGASP----QPTEKKVELVVEEVL-----QSPQGSSLSCELSVQKECED-------YSDIGGNLPVSTRPACTNKLIDYILGGASSDLDTS--SDSESEDWDEEPEDDGFDSDGS--------LSESDREQD---------SEGLHLWNSFYS-VDPYNPQNFTATIQTAARIAPRDPSDSEKSWSGNSDVG-SSQATLLPQTPDQSSGEEDDWESSADEAENLRLWNSFCNSEDPYNLLNFKAPFQTSGKSWKG---SQASSEATVVFSGHQTLLSCEAQLLESQEDNCPGCGLGEALSGERYTHIKRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEVAIGYCLTFEHRERVFSRLQDHVSKDLLLYSSAKQREQPAALTHSISYLRGFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFW3-1", "uniprot_id": "PR15B_MOUSE", "id": "Q8BFW3-1", "name": "Protein phosphatase 1 regulatory subunit 15B", "aln": "-METGTHRARKRPGPRLGSWFRLPFL-RRSHACSSEFPPPSSRQNPGN-----SALPERRTRYWTKLLSQLLALLPSLFQKLLLWSQLFGGLIPTRWLDFAASYSALRALR-GREESAAPTVQKSLSSLRLDSS-EDLVVSSLDWLEEGLQWQCSSSDLELKLKAQERALDSAAPTFLLEQQLWGVELLPSSLQAGLVSHRELDSSSSGPLSVQSLGNFKVVSYLLNPSYLDYLPQLGLRCQSSAGGGQFVGFRTLTPESCYLSEDGCHPQPLRAEMSATAWRRCPPLSTEGLPEIHHLRMKRLEFLQ-ANKGQELPTPDQDNGYHSLEEEHNLLRMDPQHCTDNPAQAVSPAADRP----EPTEKKPELVIQEVS-----QSPQGSSLFCELPVEKECEEDHTNATDLSDRGESLPVSTRPVCSNKLIDYILGGAPSDLEAS--SDSESEDWGEEPEDDGFDSDGS--------LSESDVEQD---------SEGLHLWNSFHS-VDPYNPQNFTATIQTAARIAPRDPSDSGTSWSGSCGVG-SCQEGPLPETPDHSSGEEDDWEPSADEAENLKLWNSFCHSEDPYNLLNFKAPFQPSGKNWKGRQDSKASSEATVAFSGHHTLLSCKAQLLESQEDNCPGCGLGEALAGERYTHIKRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEVAIGYCLAFEHREKMFNRLR-IESKDLLLYSNVKK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SWA1-1", "uniprot_id": "PR15B_HUMAN", "id": "Q5SWA1-1", "name": "Protein phosphatase 1 regulatory subunit 15B", "aln": "-MEPGTGGSRKRLGPRAGFRFWPPFFPRRSQAGSSKFPTPLGPENSGNPTLLSSAQPETRVSYWTKLLSQLLAPLPGLLQKVLIWSQLFGGMFPTRWLDFAGVYSALRALK-GREKPAAPTAQKSLSSLQLDSS-DPSVTSPLDWLEEGIHWQYSPPDLKLELKAKGSALDPAAQAFLLEQQLWGVELLPSSLQSRLYSNRELGSSPSGPLNIQRIDNFSVVSYLLNPSYLDCFPRLEVSYQNSDGNSEVVGFQTLTPESSCLREDHCHPQPLSAELIPASWQGCPPLSTEGLPEIHHLRMKRLEFLQQASKGQDLPTPDQDNGYHSLEEEHSLLRMDPKHCRDNPTQFVPAAGDIPGNTQESTEEKIELLTTEVPLALEEESPSEGCPSSEIPMEKEPGEGRISVVDYSYLEGDLPISARPACSNKLIDYILGGASSDLETS--SDPEGEDWDEEAEDDGFDSDSS--------LSDSDLEQD---------PEGLHLWNSFCS-VDPYNPQNFTATIQTAARIVPEEPSDSEKDLSGKSDLENSSQSGSLPETPEHSSGEEDDWESSADEAESLKLWNSFCNSDDPYNPLNFKAPFQTSGENEKGCRDSKTPSESIVAISECHTLLSCKVQLLGSQESECPDSVQRDVLSGGRHTHVKRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEDAIGYCLTFEHRERMFNRLQGTCFKGLNVLKQC--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z8R8-1", "uniprot_id": "A0A8M6Z8R8_DANRE", "id": "A0A8M6Z8R8-1", "name": "", "aln": "MSTHGHFIPGDTRSARDGDE-------RTDSSWISVFSLVSRP-------------------AWS-LLQRYFPGKTQTAFEMKSHLDIGNSLTPLNVAYLHCQHENAACVAPGDPGTLAWFTQESLSELGIQNT-SQKDFSLQKQASVGYLGTARNMLSQVLLNTQEKKRAKPESACDLCPDMVSVRSTNSWWQGGFLEANDRPPN--------LLLNVAQSRKETDTSWQHCGEHHSVGYCQS-NDGPSMHNESARPLCSKELTHNALLHMSKTELLSNSYQLPLDVG------------QQLLVCGRAYSEVAVLTPDQDNGYSSLEEEHSNSKLHMKLLSKEQEVSDTTNAVAS----EDDSSQSNTTGSELQ-----SLPILSEEEIKGGEEKESEK------TVEAAADNVSLLATPQCENKVIAYIMGSPCSGESESEEDDDDDDDWDSNDDDDGFDSEGSSHYSDSEDLDDSDDESEEDSDGEEGNSEAERLWNSLCQNGDPYNPRNFTAPIRTATKPSP-ATTDSPVSESPPAHIS-SQPSSPSSSSPSLSENESSEDVCEMDEEENRRLWNSFSCSADPYSLLNFQAPVQTK-KPPKGCRKEKAPG------MPHYKREEAEERLDSGFSEISP------VPCSSSATAIHLKKVTFVEEVEEFYASSDEDRHGPWEEIARDRCRFRRRVQEVEETISFCLSPNFRLDIFQRLFSSS------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1E4-1", "uniprot_id": "Q9W1E4_DROME", "id": "Q9W1E4-1", "name": "", "aln": "-------------------------------------------------------------------MSKFHTLMGALFDPFLFVLRLIANMSSPIYEQYRFGPSRP-------------------------------------------------------LSAGSRTLWKPNKVHQEAPEVKPLEVP--------------------------------------------------------------------------------------------------------------------------EDLRIPTLQPDP-LNPLATMMSFKLMAMDVVTQMQTALHKCVNAQS--------------------------------------------------PPGAKMAGIELDALRRCVPSSCYFFIDLHPHHGFKDTAEDCPTSQASSDRNNNAGCSQGS---------------------------AAKSSWQRQRS-ISECSEDSFICFEDDAEQADEDVEEDE-----------------------DDDDDDSSVQFTACGEDENTEELKACQCSDD----------------------------------------------------------------SSTPVKKVRFNMKPEVHVMLAWDYAYRAARKSEWQVMARDRDRFQQRIRRISPILNAVLTPVHRDRVYQARFLHED-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: . . : .: . . :.: . . :: :. . : * : * .* : . . . .: : : * . :::. . .* .: ..: :::. *:.* . *: . . . .* . * : *. . ...:.. .* *. . :: * * .. . :: : . :. : : : *:. *: :*** **::*::. . :. *: .* ::. ", "identical_positions": 25, "similar_positions": 99, "identity": "3.31%" }, { "cls_id": "homologset.agr.MGI:2444218", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PAL7-1", "uniprot_id": "AHDC1_MOUSE", "id": "Q6PAL7-1", "name": "Transcription factor Gibbin", "aln": "MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHTFSENPRPPPRRDPSSRRPPVLAKGDDLLPPRAARPVSQAHCPSPAPD-NSSLRHWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERANPHTKSERPSHPLYEPEPEPRDSPQPGQGHGPGAAATATGLPPEPEPDGPDYSELADADILSELASLTCPEAQLLEAQALEPPSPQPEPQLLDPQPRFLDPQALEPLGEGLELPPLQPLADPLGLPSLTLQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQSLGHCQLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADSGPEGRLLPLPMPTGLAAALAEPPPLPPPPPPTLSGP--GPVPELEPESSQTPMVPTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSSEPTPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLLLGPGKPKEPTVVAAEAATVTAATMAMPEVKKRRRRKQKLASPQPSYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISQFLHRVQGFRRRGGKTGGFGGRGGGHAAKAARCSFSDFFEGIGKKKKVVAVAAPGLVGPGLTELGHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWVGDKGGGWAPHHGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYY-AGAPSGQTELSQERQNLFTGYFRSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPSSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLPSRQTFPPGRATSYGITPATSDCRAAETFPKLAPPPSAVARSPTTHPPANTYPPQYGGYGAGQSVFASAKPFSGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFNSSEGGPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTAS---AASVASSSSSSFQPSPENCRQFVGASQWPFRQGYGGLDWASEAFSQLYNPNFDCHGSEPNVILDISNYTPQKVKQQTAVSETFSESSSDSTQFSQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFSTSTSATASGYPSKRSTGPRQPRGGRGSGACSAKKERGGTAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFMGPYSMNPSTPSDGTFGQGFHCDSPSLGAAELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPSKLTACEPLKHGLQGASLSH--AAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGSGLLADFLGRTEAVCLSAPHLASPPATPKADKEPLEMARPPGPPRGPAAATAGYGCPLLSDLTLSPVPRDSLLPLQDTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A5R3-1", "uniprot_id": "D4A5R3_RAT", "id": "D4A5R3-1", "name": "", "aln": "MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHTFSENPRPPPRRDPSSRRPPVLAKGDDLLPPRAARPVSQAHCPTPAPD-NNSLRHWDNGRVNLHPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKPERPNHPLYEPEPEPRDSPQPGQGHGPGATATATGLPPEPEPDGPDYPELADADILSELASLTCPEAQLLEAQALEPPSPQPEPQLLDPQPRFLDPQALEPLGEGLELPPLQPLADPLGLPSLTLQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQSLGHCQLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKVDSGPEGRLLPLPMPTGLAAALAEPPPLPPPPPPPALS---GPVPELEPESSQTPMVPTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSSEPTPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLLLGPGKPKEPTVVAAEAAAVTAATMAMPEVKKRRRRKQKLASPQPSYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISQFLHRVQGFRRRGGKTGGFGGRGGGHAAKAARCSFSDFFEGIGKKKKVVAVAATGVVGPGLTELGHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPHHGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYY-AGAPSGQTELSQERQNLFTGYFRSLLDSDDSSDLLDFALSASRPESRKASGNYAGPPSSALPAQRGLATFPSRGAKGSPVAVGNSGAGTDPSFQPVLPSRQTFPPGRATSYGITPATSDCRAAETFPKLAPPPSAVARSPTTHPPANTYPPQYGGYGAGQSVFAPAKPFSGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFNSSEGGPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTAS---AASAASSSSSSFQPSPENCRQFVGASQWPFRQGYGGLDWASEAFSQLYNPNFDCHVSEPNVILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGG-FRRANSEASSSEGQSSLSSLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFSTSTSATASGYPSKRSTGPRQPRGGRGSGACSAKKERGGTAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFMGPYSMNPSTPSDGTFGQGFHCDSPSLGAPDLDSKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPSKLTACEPLKHGLQGASLSH--AAQAHLSCRDLPLGQPHYESPSCKGTAYWYPPGSAARSPPYEGKVGSGLLADFLGRTEAVCLSAPHLASPPATPKADKEPLEMTRPPGPPRGPAAATAGYGCPLLSDLTLSPVPRDSLLPLQDTAYRYPGFMPQTHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TGY3-1", "uniprot_id": "AHDC1_HUMAN", "id": "Q5TGY3-1", "name": "Transcription factor Gibbin", "aln": "MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLLLGPGKPKEPAVVAAEAATVAAATMAMPEVKKRRRRKQKLASPQPSYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISHFLHRVQGFRRRGGKAGGFGGRGGGHAAKSARCSFSDFFEGIGKKKKVVAVAAAGVGGPGLTELGHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPHHGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYSTGAPSGQTELSQERQNLFTGYFRSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSSFQPSPENCRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFPTSASAAASGYPSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPLQDTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************************************************:**************:*********** ************:**:*. * ..* * ********:*****************************************************************.**:*.***.********************.***:*:***********..**.********************************:***********************.****************.*:***************************************.**** **********************************************.*:***************.******** ******. . .****:*******:*.****************************************************:*************************************************:*******:*:*********************************************************************************:**************:*************:***********************.*: *******************************************************.************************************************ :**************************************************.*****:******************.******.****:********.:*********:***:***:************.*****:************* **************.:***:**************************************************.****.********************************* ***.******************.***************************.**** *************************************.****** ********************************************************************.**:**:********************.***********:******************************************************:****************************.:**.***************************************:**:**************.* ******************:***************************:************.***********************:************:*************************************:******************************", "identical_positions": 1498, "similar_positions": 82, "identity": "93.45%" }, { "cls_id": "homologset.agr.MGI:2444222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZU40-1", "uniprot_id": "D3ZU40_RAT", "id": "D3ZU40-1", "name": "Putative sodium-coupled neutral amino acid transporter 12", "aln": "MAGEIT--ETGELYSPYVGLVYMFNLIVGTGALTMPKAFATAGWLVSLILLVFVGFMSFVTTTFAMEAMAAANAQLRWKRMEIHKEEDDEDSSTASDS---DLLSQDNYERAE--KRPILSVQRRSSASLFEITERVEMGQMASMFFNKVGVNLFYFCIITYLYGDLAIYAAAVPVSLMQVTCSVSGNDSCG----VDTDAKYNDTDLCWGP--LRRVDVYRIYLAIFTVLLGPFTFFDVQKTKYLQILTSLMRWIAFAIMIVLALVRIGKGQGEGHPPLANFLGVQNLFGVCVYSFMCQHSLPSLITPISSKRHITRLLFLDYALILAFYGLLSFTAIFCFRGDSLMDMYTLNFAR-----CDVVG--LAAVRFFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYPW-VVDRVVFPTITLVPPILVAFCTHDLESLVAITGAYAGTGIQYVIPAFLVFLCRKDTQLTFGSGTINKHRSPFGHTFWVAFVLLWAFSCFFFVTAYIVLKETQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TB48-1", "uniprot_id": "S38AC_MOUSE", "id": "Q3TB48-1", "name": "Putative sodium-coupled neutral amino acid transporter 12", "aln": "MAGEIT--ETGELYSPYVGLVYMFNLIVGTGALTMPKAFATAGWLVSLVLLVFVGFMSFVTTTFAMEAMAAANAQLRWKRMETHKEEDDEDSSTASDS---DLLSQDNYERAE--KRPILSVQRRSSANLFEITDRVEMGQMASMFFNKVGVNLFYFCIITYLYGDLAIYAAAVPVSLMQVTCSVSGNDSCG----VDTDARYNDTDLCWGP--LRRVDVYRIYLAIFTVLLGPFTFFDVQKTKYLQILTSMMRWIAFAIMIVLALVRIGKGQGEGHPPLANFLGVQNLFGVCVYSFMCQHSLPSLITPISSKRHITRLLFLDYALILAFYGLLSFTAIFCFRGDSLMDMYTLNFAR-----CDVVG--LAAVRFFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYPW-VVDRVVFPTITLVPPILVAFCTHDLESLVAITGAYAGTGIQYVIPAFLVYLCRKDTQLTFGYGTVNKHRSPFRHTFWVAFVLLWAFSCFFFVTAYIVLKETQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NE00-1", "uniprot_id": "S38AC_HUMAN", "id": "Q8NE00-1", "name": "Putative sodium-coupled neutral amino acid transporter 12", "aln": "MAGEIT--ETGELYSSYVGLVYMFNLIVGTGALTMPKAFATAGWLVSLVLLVFLGFMSFVTTTFVIEAMAAANAQLHWKRMENLKEEEDDDSSTASDS---DVLIRDNYERAE--KRPILSVQRRGSPNPFEITDRVEMGQMASMFFNKVGVNLFYFCIIVYLYGDLAIYAAAVPFSLMQVTCSATGNDSCG----VEADTKYNDTDRCWGP--LRRVDAYRIYLAIFTLLLGPFTFFDVQKTKYLQILTSLMRWIAFAVMIVLALIRIGHGQGEGHPPLADFSGVRNLFGVCVYSFMCQHSLPSLITPVSSKRHLTRLVFLDYVLILAFYGLLSFTAIFCFRGDSLMDMYTLNFAR-----CDVVG--LAAVRFFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYPW-VVDRVVFPTITLVPPVLVAFCTHDLESLVGITGAYAGTGIQYVIPAFLVYHCRRDTQLAFGCGVSNKHRSPFRHTFWVGFVLLWAFSCFIFVTANIILSETKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9F2-1", "uniprot_id": "E7F9F2_DANRE", "id": "E7F9F2-1", "name": "Putative sodium-coupled neutral amino acid transporter 12", "aln": "MAGGIT--ETGEPYSPFVGLVYMFNLIVGTGALTMPKAFAAAGWVVSVSLITFLAFMSFMTTTFVIEAMAAANAQLRWKRREQEEVNDSDSSSDYSDD---EVIIRGRSEPVE--TRPILSVQRAANIDHFDIVERVEMGQMASMFFNKVGVNMFYICIIVYLYGDLAIYAAAVPVSLMEVAC---GNHSCS----AGS-VKYNDTESCWGP--VRRKDAYRVFLAIFTLLLGPFTFFNAQKTKYLQILTSLMRWIAFTMMIILALIRIGKGHGEGKPSVAQISGVPNLFGVCVYSFMCQHSLPSLVTPISNKQRMSILVMADYILILCFYALLSLTAIFCFDSSLLRDMYTLNFTDN----CDVLG--VPVLRYFLGLFPVFTISTNFPIIAVTLRNNWKTLFHRDGGTYPW-VVDRVVFPLITLVPPIIVAFCTHDLESLVGITGAYAGTGIQYIIPAFLVYFSRRHLEPVLGRDAVNKHRSPFRHTFWVCFVVLWATFCLMFVTANIVLNETKN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPF8-1", "uniprot_id": "S38AC_DROME", "id": "Q9VPF8-1", "name": "Putative sodium-coupled neutral amino acid transporter 12", "aln": "MPRLVNGREAAPTYSNLVGFIFIFNLIVGTGALTLPGVFARAGWMLSLIVIVLLAIISYMTVTFIIEAMACANAIRNWQTLQALRQSRSSAENSENDDNADDVSLASGAEQVGDFERVPLTIQNR-EFHYYQLSHKFELGEMATLFFNEFGRVMFYLCLIVYLYGDLSIYSAAVARSLRDVVCDQTNGTDTNNLMYWPGDFENNTSLACWKEHTISRLNMYRVLLIGFTLIFGPFVYFNVQKTKYLQMLTAAFRWMAFTLMICISLKLLISRGAKGHPATFNVYGIPSLFGACVYSFMCHHSLPSLLAPIRHKSMVSKILSIDYIIICAFYILLAMTGIFAFER--IEDLYTLDFLPYDVAYVDFWSGLLICIDYFLALFPIFTLSTSFPIVAITLKNNLQSLFLDMSQYESYSVILRLCFPLLAIIPPFCITYFTESLSSLVAFTGTYAGTGIQYIIPVFLVYFARRTCSELLGSGVVNRFKSPFKSSAWLVFVFIWSILCVCLVSINLFS-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :. *:. ** **::::***********:* .** ***::*: ::.::.::*::*.** :****.*** .*: : . . .. .. .*. :: . * . * *::*. . ::: .:.*:*:**::***:.* :**:*:*.******:**:***. ** :*.* .. . . . * : ** : * : **: * **:::***.:*:.*******:**: :**:**::** ::* : .:*:*. :. *: .***.*******:******::*: * :: :: ** :* .** **::*.**.* : *:***:* *. . : : :**.***:**:**.***:*:**:** ::** . .: *: *: ** ::::**. ::: *..*.***.:**:********:**.***: .*: . :* .. *:.:*** : *: **.:*: *. :*: :. ", "identical_positions": 192, "similar_positions": 173, "identity": "37.14%" }, { "cls_id": "homologset.agr.MGI:2444223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHJ6-1", "uniprot_id": "SERC5_MOUSE", "id": "Q8BHJ6-1", "name": "Serine incorporator 5", "aln": "MSARCCAGQLACCCGSAGCSLCCGCCPKFRQSRTTRFMYLFYFILVIALCCVMMTPSVMKQVKDHIPFFEEFCKKTQAGGDACENLVGYSAVYRVCFGMACFFALFCLLTLKVNNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLKVWRYVGAGGSFLFICIQLLLIVQFAHKWNKNWTAGTVRN----KLWYASLSLVTLIMYSVAVGGLALMAVFYTQWDDCMDNKILLGVHGGLCVLISLVAISPCVQNRQPHSGLLQSGLISCYVTYLTFSALTSKPEK-----KVLDEHGKNVTICAPDFGQDLHRDENMVTWLGTLLLIVCISYSCLTSTTRSSSDALQS-RYGAPELEVARCCFCFG--PDGEDTEEQQNVKKGPR-----VIYDEKKGTVYSYSYFHFVFFLASLYVMMTLTSWFHYENATIKTFFSG-WSVFWVKMASCWMCVLLYLQTLVAPLCCPSRQFSV---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63175-1", "uniprot_id": "SERC5_RAT", "id": "Q63175-1", "name": "Serine incorporator 5", "aln": "MSARCCAGQLACCCGSAGCALCCGCCPKFRQSRSTRFMYLFYFTLVIIPCCVMMSPSVMKQMTEHIPFFEDFCKGIKAG-DTCENLVGYSAVYRVCFGMACFFFVFCVLTFKVNNSKSCRASIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNVWRYVGAVGSFFFICIQLLLIVEFAHKWNKNWTAGTVRN----KLWYASLSLA-LIMYSIAVGGLALMAVFYTQWDDCMDNKILLGVHGGLCVLISLAAISPCVQNRQPHSGLLQPGLISCYVTYLTFSALTSKPEK-----VVKDEHGKNVTICVPDFGQDFRRDESMVTWLGTLLLVVCISYSCLTSTTRSSSDALQR-RYGAPELEVARCCFCFG--PDGEDTEEQQNVKEGPR-----VIYDEKKGTVYSYSYFHFVLLLASLYVMMTLTSWFHYENATIETFFVGSWSIFWVKMASCWMCVLLYLWTLVAPLCCPSRQFSV---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VE9-1", "uniprot_id": "SERC5_HUMAN", "id": "Q86VE9-1", "name": "Serine incorporator 5", "aln": "MSAQCCAGQLACCCGSAGCSLCCDCCPRIRQSLSTRFMYALYFILVVVLCCIMMSTTVAHKMKEHIPFFEDMCKGIKAG-DTCEKLVGYSAVYRVCFGMACFFFIFCLLTLKINNSKSCRAHIHNGFWFFKLLLLGAMCSGAFFIPDQDTFLNAWRYVGAVGGFLFIGIQLLLLVEFAHKWNKNWTAGTASN----KLWYASLALVTLIMYSIATGGLVLMAVFYTQKDSCMENKILLGVNGGLCLLISLVAISPWVQNRQPHSGLLQSGVISCYVTYLTFSALSSKPAE-----VVLDEHGKNVTICVPDFGQDLYRDENLVTILGTSLLIGCILYSCLTSTTRSSSDALQG-RYAAPELEIARCCFCFS--PGGEDTEEQQPGKEGPR-----VIYDEKKGTVYIYSYFHFVFFLASLYVMMTVTNWFNHVRSAFHLLP-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q803X0-1", "uniprot_id": "SERC5_DANRE", "id": "Q803X0-1", "name": "Serine incorporator 5", "aln": "MCTPCCVSQLACCCGSAACSLCCGCCPKIKQSTSTRFMYALFFMLVTVTCVIMMSPTVEMAMREHIPFYSQMCQQLNAG-ENCSTLVGYSAVYKVCFGMACFFFFFAVFTIRVQNSTGCRAAVHNGFWFFKFVALLACCAGGFFLPNQDQFLEVWRYVGAAGGFLFIIIQLMLLVQFAHRWNQNWSSGATYN----KLWYAALALVTLVLFSVAVGGMVFMFMYYTHPEACFLNKIFLGVNGGLCFIVSLLAISPCIQTFQPTSGLLQPAVITLYVMYLTFSALASKPIE-----MVEDEIKGNITVCVFPFKSGLKSDTNIVTGVGTAILFCCILYSCLISTTKRSSAALQVYRNDMPENERARCCFCWV--DDTEDYDDEK-TSGGQN-----VKYDERDGTVYSYCFFHFVFFLGSLYVMMTVTNWFHYDNAKIERLLEGSWSVFWIKMASSWVCLFFYMWTLVVPMLFPQRFQA----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12116-1", "uniprot_id": "TMS1_YEAST", "id": "Q12116-1", "name": "Membrane protein TMS1", "aln": "--MGAVISLPVSMAGSFVASCFGGCCSNLVTKTASSLGSSSLGTRLLYAVWLLLN-----SLISWVSYSANKSILWPGKTCTGTGECGFFTVHRLNFALGCLHLILALVLTGVKSTNDVRAALQNSWWSLKFILYLCLIVLSFVIPN-DFYIFFSKWVSVPSGAIFILVGLILLVDFAHEWAETCISHVESEDEDSSFWQRFLVLGTTSMYTASIIMTVVMYVMFCH-QQCNMNQTAVTVNLILTVITLVLSVNPKIQEANPKSGLAQSSMVSVYCTYLTMSAMSSEPDDKMCNPLVRSSGTRKFSIILGSLFTFIAIAYTTTRAAANSAFQGTNTNGAIYLGNDIEYEGLGGQTRNQLRYEAIKQAVEEGSLPESALYDTAWLGTSSPTGAMDNQNDDERTGTKYNYTLFHVIFFLATQWIAILLTINVTQDDVGDFIPVGRTYFYSWVKIVSAWICYALYGWTVVAPAIMPDRFDYENYY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .. .** .: .**..: . :: : : :::. : . :.: : . . *: :*::: *.:.*:. .:.:. ::.:.. ** ::*.:* :*:: . .*.:*: : :: ::*.. .. :** : *:*:*:***.* :. : . : .:* * * ::: : ..* : : : : * *: : *: * .: : ::.* :* :* *** *..::: * ***:**::*:* . * .. :.:: : : . . .. : ..: . . .* . * : .. : . . **: ** * * **.:::*.: :: : :* . ", "identical_positions": 61, "similar_positions": 152, "identity": "12.66%" }, { "cls_id": "homologset.agr.MGI:2444227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1Y0-1", "uniprot_id": "RHOV_RAT", "id": "Q9Z1Y0-1", "name": "Rho-related GTP-binding protein RhoV", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPRELSEAEPPPLPASTPPPR--------------------------------RRS-------------------------APPELGIKCVLVGDGAVGKSSLIVSYTCNGYPSRYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPEPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDU1-1", "uniprot_id": "RHOV_MOUSE", "id": "Q8VDU1-1", "name": "Rho-related GTP-binding protein RhoV", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPRELSEAEPPPLPASTPPPR--------------------------------RRS-------------------------APPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96L33-1", "uniprot_id": "RHOV_HUMAN", "id": "Q96L33-1", "name": "Rho-related GTP-binding protein RhoV", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPRELSEAEPPPLRAPTPPPR--------------------------------RRS-------------------------APPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0KHU4-1", "uniprot_id": "Q0KHU4_DROME", "id": "Q0KHU4-1", "name": "", "aln": "MTVKLAKLFGGVTTGGIEILDSPGNPQQHQEQQHLQQQQQQPLTAPQQHMQQQPPPLPPPNANMKSLKYYEHLQATYDCHDLMDHDQDQDDYEDTCMQRNHPYNNSQRPLLGDRRPQLTVMSVGKKGAKSGMQVQNLPPLPPLRTYISPYVQQQKRDSAKGLHGFNDFDALSQQYNQHLQSPHIGYPYGSPPSPTAQSSDFCFDRQTGLVMLPGTAGGQVSSSSSSNCSSSHTTSTSSPTRYYPDNPGHATGLFASRFEDDFCMRRPAVQESSSPIIAGGCGGGTGSGSGVALGVGGGPFIFGIAPEQQVTDYGSNPLPPTPPQLKQQSVISRSPLQQSLSDTSAASSGKGSKFLLRKRKSKKTTAAAAATTEAATTAKKDGKKAIAQPQPSIKCVLVGDGAVGKTNLILSYLENRFNPEHIPTASDIYNADVNVNESPVHLTICDTAGQDTLDPLRELCYPDSDVFLLCFSVVKPETFRAIKTKWAPKFAKT--KAALILVGTQADLRTSPNVLNKLQTNGEE-AISYADAWDLATTIGAK-YIETSSATQDKVKDVFDTAIWEGLVPTT-----------LPPTPSFWRKLFCLA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::::: . ** ...* : *:* * *: .*************:.**:** * : ..: *** * :..:* *: :**:: : *****: :* **.*****:**** *****:*.:*: *. ** *:: . :*.::********* . *** :*: .*.* .:. .:* .** .* * *:* *: **.::*:***:** ..: .: . : . *:*:**:.", "identical_positions": 98, "similar_positions": 76, "identity": "16.42%" }, { "cls_id": "homologset.agr.MGI:2444228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LM55-1", "uniprot_id": "F1LM55_RAT", "id": "F1LM55-1", "name": "", "aln": "MSQFKRQRINPLPGGRNFSGAASTSLLGPPPGLLTPPVATDLSQNARHLQSGEKQRVFTGIVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQPLLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLS---LFQTSHTLHLSHLNRFPARG-------------PHGRLDQGRS-----DDYDSKKRKQRAGGEPWGAKKPRHDLPPYRVHLTPYAVDSPTCDFLELQRRYRSLLVPSDFLSVHLSWLSAFPLGQPFSLHHPSRIQVSSEKEAAPDTGAEPSPEDSDPTYSSKVLLLSSPGLEEFYRCCMLFVDDMAEPRETPEHPLKQLKFLLGRKEEEAVLVGGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSTCTKWWRFAEFQYLQPGPPRQLHTVVVYLPDVWTIMPTLEEWEALCQQKATEAAPQPQEASGEAEATEQAPDVSEQ-ADTSKQDTETAEATTQQDVDTELPEAPPPPLEPAVMARPGCVNLSLYGIVEDRRPKERISFEVVVLAELFVEMLQRDFGYRIYKVLLSLPEKVVSPPEPEKEEAAKEDVVKEEEAVKEEAVKVSKDEVQNEGTAAEADSPLKEDGLLPKQPSAGGEEEEKARGEAAEDLCEMALDPDLLLLRDDGEEEFAGAKLEETEVRSVASNQSEMEYSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVAQNICQYRSLQYSRAEALDDGLPEDVLFGNLDLLPPSGKSTKPGAAPTEHKGLVPHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRARLAEAEETARTVERQKNQLQRQMQDFRRRLTPLHLEMQRIVEKADSWVEKEEPTPSN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDP4-1", "uniprot_id": "CCAR2_MOUSE", "id": "Q8VDP4-1", "name": "Cell cycle and apoptosis regulator protein 2", "aln": "MSQFKRQRINPLPGGRNFSGAASTSLLGPPPGLLTPPVATDLSQNARHLQSGEKQRVFTGIVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQPLLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLS---LFQTSHTLHLSHLNRFPARG-------------PHGRLDQGRS-----DDYDSKKRKQRAGGEPWGAKKPRHDLSPYRVHLTPYTVDSPTCDFLELQRRYRSLLVPSDFLSVHLSWLSAFPLGQPFSLHHPSRIQVSSEKEAAPDTGAEPSPEDSDPTYSSKVLLLSSPGLEEFYRCCMLFVDDMAEPRETPEHPLKQLKFLLGRKEEEAVLVGGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSTCTKWWRFAEFQYLQPGPPRQLHTVVVYLPDVWTIMPTLEEWEALCQQKATEAAPQPHEASGEAEATEQAPDVSEQ-ADTSKQNTETMEATTQQDVDTDLPEAPPPPLEPAVMARPRCVNLSLYGIVEDRRPKERISFEVVVLAELFVEMLQRDFGYRIYKTLLSLPEKVVSPPEPEKEEAAKEDAVKEEEAVKEEAVKVSKDEVQNEGTAAESDSPLKEDGLLPKRPSSGGEEEEKARGEAAEDLCEMALDPDLLLLRDDGEDEFAGAKLEETEVRSVASNQSEMEYSSLQDMPKELDPSTVLPLDCLLAFVFFDANWCGYLHRRDLERVLLTLGIRLSAEQAKQLVSRVVAQNICQYRSLQYSRAEVLDDGLPEDVLFGNLDLLPPSGKSTKPGAAPTEHKGLVPHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRARLAEAEETARTAERQKNQLQRQMQDFRRRLTPLHLEMQRIVEKADSWVEKEEPTPSN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N163-1", "uniprot_id": "CCAR2_HUMAN", "id": "Q8N163-1", "name": "Cell cycle and apoptosis regulator protein 2", "aln": "MSQFKRQRINPLPGGRNFSGTASTSLLGPPPGLLTPPVATELSQNARHLQGGEKQRVFTGIVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQPLLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLS---LFQTSHTLHLSHLNRFPARG-------------PHGRLDQGRS-----DDYDSKKRKQRAGGEPWGAKKPRHDLPPYRVHLTPYTVDSPICDFLELQRRYRSLLVPSDFLSVHLSWLSAFPLSQPFSLHHPSRIQVSSEKEAAPDAGAEPITADSDPAYSSKVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRKEEEAVLVGGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGPPRRLQTVVVYLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAETPEATTQQETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPAPSN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UVX0-1", "uniprot_id": "A0A8N7UVX0_DANRE", "id": "A0A8N7UVX0-1", "name": "", "aln": "------------------------------------------------METQMRQRVFTGVVTQMQEHHGIVDQDVHFPMSVVVGRMPVVGEKVLVKAIQDSQKPISWTAQKVQTLNGQPFKSP--PPLLPSMSSTLKPGILGTKPQPLLKSPKIPPLIPSMQPNSGGMIQLSHHQQMGWNGPFDGWGGGRKRHSEGMGGRRAGRWEDGGGGLWGGDLMHQKRKRWRATSEEEAPKKTSSAATHSVPLFSCFSRDTQACDYLELQRRYPHLHIPSSLFHLQLSWTESFPLDQPLPLRGPCLFHIGPNQ---PETEAD-VCESTDDAFAVRVLLFSMPCLEDVYSQCCNLSNDGQ-TQKEAVHPSTLLKFLIVDSGGEQRLPGGHWSPEADGANPAKDSLTLVNTAVRCLKEQAGLDLSACTQWYKMAELRYLSGD---KVETVVVLMPDVWNLVPSEEEWASLQLEDDLSLPESPSVVFHPSAGLNLSAVSLSS------------------------------LLEPQTLQTRDSCEDHLLTSVMCCR-------QVSLIAEMFSEMLQRDFGLQLYRCLCSLPQNISDPQTEAKQ--DNNTAKEEEEEIKKSDKKTTKKKDSSDARKTVKEEKDAEDAMLTDETEAVGKQPSR-----------------------DGKTVSAGVEEQSS---------NAADNQTSKHCERPPGWTDELPRKVLLSCVFFDRQLTGSLREADLVNILLSLGLFLSPAQAQDLVKRAAVGGLCLYRNLCSRWSDSAPS-DASAIAEGNKAMLPTQPCKDRGSVRRTSNTDVVNYKGKVVNLPNLLQCLESSKVAQRDLEKSVAALQSRLDAAEALQASSEQE----LAQQKELKRKLEKAEMINKTYEKS-------LKENAGQMTAVIEKMQRMVEQTTTITNANAGKEEKL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :******:**.::::.*:**::*.* :*** **:* :******** :. :.:.*.* *****..**: .. **** : * ****::** :::. :****:*. . ::* ** ::. . * . * ** ::* . * ..*::: ** .* ..**. . :: :: *: **:******* * :**.:: ::*** .:***.**:.*: *. :::..:: *:: *: .:* ::: :***:* * **:.* * : :* .:: . ** . :***: . * * **.***. ** :* *. .**.**:** : *:*:*** **:*:::**::**. . ::.**** :****.::*: *** :* :. . . . . : : :. .. *** .: . : * * * :* ::**:* ******** ::*: * ***::: .* *: :: . :*** :*:. * .*.: ..:. : : **.:*.. .: *:: .: **: **.: :.: . : .: :. : . : ** . **: **** : * *:. ** .:**:**: **. **::**.*... .:* **.* : . .. : ** :**. . : .. *.:. :* ::*.::*: .*** *... .: **:.: :*: :*: :. :::* *: :**: :* :** :* *:. ::: ::*.: ::**:**:: : .: : .: ", "identical_positions": 246, "similar_positions": 288, "identity": "26.03%" }, { "cls_id": "homologset.agr.MGI:2444232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V9D0-1", "uniprot_id": "PGLT1_RAT", "id": "G3V9D0-1", "name": "Protein O-glucosyltransferase 1", "aln": "MERLSGCRLRPWMLLLLLFP--------VQGRQKDSGSKWKVFID----------QINRALENYEPCSSQ----NCSCYHGVIEEDLTPFRG-GISRKMMAEVVRRRLGTHYQIIKHRLFREDDCMFPSRCSGVEHFILEVIRRLPDMEMVINVRDYPQV-PKWMEPT-IPVFSFSKTSEYHDIMYPAWTFWEGGPAVWPLYPTGLGRWDLFREDLLRSAAQWPWEKKNSTAYFRGSRTSPERDPLILLSRKNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLIDHCKYKYLFNFRGVAASFRFKHLFLCGSLVFHVGDEWVEFFYPQLKPWVHYIPVKTDLS--DVQELLQFVKANDDLAQEIAKRGSQFIINHLQMDDITCYWENLLTEYSKFLSYNVTRRKDYYQIIPRRLKTEL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYB9-1", "uniprot_id": "PGLT1_MOUSE", "id": "Q8BYB9-1", "name": "Protein O-glucosyltransferase 1", "aln": "MERRAGSRLRAWMLLLLLCP--------VQGRQKDSGSKWKVFLD----------QINRALENYEPCSSQ----NCSCYHGVIEEDLTPFRG-GISRKMMAEVVRRKLGTHYQIIKNRLFREDDCMFPSRCSGVEHFILEVIHRLPDMEMVINVRDYPQV-PKWMEPT-IPVFSFSKTSEYHDIMYPAWTFWEGGPAVWPLYPTGLGRWDLFREDLLRSAAQWPWEKKNSTAYFRGSRTSPERDPLILLSRKNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLIDHCKYRYLFNFRGVAASFRFKHLFLCGSLVFHVGDEWVEFFYPQLKPWVHYIPVKTDLS--NVQELLQFVKANDDIAQEIAKRGSQFIINHLQMDDITCYWENLLTDYSKFLSYNVTRRKDYYQIVPRRLKTEL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBL1-1", "uniprot_id": "PGLT1_HUMAN", "id": "Q8NBL1-1", "name": "Protein O-glucosyltransferase 1", "aln": "MEWWASSPLRLWLLLFLLPS--------AQGRQKESGSKWKVFID----------QINRSLENYEPCSSQ----NCSCYHGVIEEDLTPFRG-GISRKMMAEVVRRKLGTHYQITKNRLYRENDCMFPSRCSGVEHFILEVIGRLPDMEMVINVRDYPQV-PKWMEPA-IPVFSFSKTSEYHDIMYPAWTFWEGGPAVWPIYPTGLGRWDLFREDLVRSAAQWPWKKKNSTAYFRGSRTSPERDPLILLSRKNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAASFRFKHLFLCGSLVFHVGDEWLEFFYPQLKPWVHYIPVKTDLS--NVQELLQFVKANDDVAQEIAERGSQFIRNHLQMDDITCYWENLLSEYSKFLSYNVTRRKGYDQIIPKMLKTEL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8T045-1", "uniprot_id": "RUMI_DROME", "id": "Q8T045-1", "name": "O-glucosyltransferase rumi", "aln": "---MLINHLIVVLLISLVGTGGAEDDGLCSADQKSCAQSEPDQINEDEFSFKIRRQIEKANADYKPCSSDPQDSDCSCHANVLKRDLAPYKSTGVTRQMIESSAR--YGTKYKIYGHRLYRDANCMFPARCEGIEHFLLPLVATLPDMDLIINTRDYPQLNAAWGNAAGGPVFSFSKTKEYRDIMYPAWTFWAGGPATK-LHPRGIGRWDQMREKLEKRAAAIPWSQKRSLGFFRGSRTSDERDSLILLSRRNPELVEAQYTKNQGWKSPKDTLDAPAADEVSFEDHCKYKYLFNFRGVAASFRLKHLFLCKSLVFHVGDEWQEFFYDQLKPWVHYVPLKSYPSQQEYEHILSFFKKNDALAQEIAQRGYDFIWEHLRMKDIKCYWRKLLKRYVKLLQYEVKPEDQLIYIGPK--KDEL---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCU4-1", "uniprot_id": "Q9VCU4_DROME", "id": "Q9VCU4-1", "name": "Glycosyl transferase CAP10 domain-containing protein", "aln": "MTQPRICFLVGALILSCTCVSCSKDK-CAVNEHNPNSNTSYDFVP----------HILHALAIHRPCVIG--DPKCLCHVATIQRDLEPYVDKGITPEMMAQSKR--LGTFYQIIRGRIYRQQKCLHPKRCADVEDLLLDMASGVADLEFVLNVRDWPQV--HFLSGLSGPVFSYSITNRHLDIMYPAWSFWTTTGPILQHYPHGVGRWDWMRKHLVARASELPWSAKRAIGFFRGSRSSPERDSLVRLSQRRPDLVDAQYT--------ILATDADPVEKMPLVEHCQFKYLFNFRGVAASFRLRHILLCRSLVLHVGDQWQEFFYSQLKPWVHYVPVASDADVDELAELILYLREHDDLAEEIAERGQQFIWLHLRMEDVQCYWSKMLQEYAKLLTYKVQREPGLLEVSNKKAVQLYRGK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::: :: ... : :* :: :.** .* *: .::.** *: . *:: :*: . * ** *:* *::*: .*:.* ** .:*.::* : :.*:::::*.**:**: : . ****:* *..: *******:** . :* *:**** :*:.* *: **. *.: .:*****:* ***.*: **::.*.**:*:** : . ....: : :**:::*************::*::** ***:****:* **** ********:*: : . : .:: :.: :* :*:***:** :** **:*.*: *** ::* * *:* *:* . : : ", "identical_positions": 136, "similar_positions": 122, "identity": "32.23%" }, { "cls_id": "homologset.agr.MGI:2444233", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y5A9-1", "uniprot_id": "YTHD2_HUMAN", "id": "Q9Y5A9-1", "name": "YTH domain-containing family protein 2", "aln": "MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFAN-ETLNKAPGMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKG--PVAKAPSQALVQNIGQP-TQGSPQP------VGQQANNSPPVAQASVGQQTQPLPP------PPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSG--STPSEPHPVLEKLRSINNYNPKDFDWNLK-HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKG-PVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQD-KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91YT7-1", "uniprot_id": "YTHD2_MOUSE", "id": "Q91YT7-1", "name": "YTH domain-containing family protein 2", "aln": "MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFAN-ETLNKAPGMNTIDQGMAALKLGSTEVASSVPKVVGSAVGSGSITSNIVASSSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKG--PVAKAPSQALVQNIGQP-TQGSPQP------VGQQANNSPPVAQASVGQQTQPLPP------PPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSG--STPSEPHPVLEKLRSINNYNPKDFDWNLK-HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKG-PVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQD-KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK----------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ABJ9-1", "uniprot_id": "A0A8I6ABJ9_RAT", "id": "A0A8I6ABJ9-1", "name": "YTH domain-containing family protein", "aln": "ARRRPLLSQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFAN-ETLNKAPGMNTIDQGMAALKLGSTEVASSVPKVVGSAVGSGSITSNIVASSSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKG--PVAKAPSQALVQNIGQP-TQGSPQP------VGQQANNSPPVTQTSVGQQTQPLPP------PPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSG--STPSEPHPVLEKLRSINNYNPKDFDWNLK-HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKG-PVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQD-KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKNAKRKKKVLKRNVKAVGNKKRFCIDCSNGCVCLS-------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E7F1H9-1", "uniprot_id": "YTHD2_DANRE", "id": "E7F1H9-1", "name": "YTH domain-containing family protein 2", "aln": "MSASSLLEQRPKGQANKVQNGAVTQKDTLNDDEFEPYLNAQPRQSNAYTAMSDSYMPSYYSPSIGFTYSLNEAAWSTGGDPPMPYLASYGQLSNGEHHFLPDAMFGQSGALGNNPFLGQHGFNFFPSGIDFPAWGNSSSQGQSTQSSGYSSSYAYAPSTLGGAMIDGQSPFAANEPLNKAVGMNSLDQGMAGLKIGAGDMA---PKVVGSGLPGGPLS-QVSTAPTMPPASMAPAKTASWADIASKPAKPQPKLKTKGGLGGTNLPPPPIKHNMDIGTWDNKGNMPKPAAPQQTSLPTNGQPPNQSSPQPGATAGGVPQLPLSNGQLVPPTGQLVQHPLPPGGQPGAVPPQLSQGPPASQPSQPTRWVPPRNRANGFG-DAAGGPGQSPPNSGMGGITVPAEPHPVLEKLRMVNNYNPKDFDWNPK-HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSLANKG-PLYLLFSVNGSGHFCGVAEMRSPVDYNTCAGVWSQD-KWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLDKARQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKVEVQGSDPYSNNSSRSHYRMQDRQGRVK-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBZ5-1", "uniprot_id": "YTHDF_DROME", "id": "Q9VBZ5-1", "name": "YTH domain-containing family protein", "aln": "-MSGVDQMKIPGNTAKSVEERNIPWSQQVDEASYENLSSP----THDEVSGNDNSMQFQYPPFNFKENCNTPWNNMNKGRKANANHDSYRRHGHSIPNNTRRDEHQVNPWNSRKPAAQSFRNENDQPSTKLDNRTSDEAQNQEVVAAPKKTTWASIASQPAKLTSRAASTTSNSKKKGPGMPPPPMVPGKHNLDVNVWDLPNNKPPPVPSPPSPIDLGYSDLSSDFSISSNTAPP-LGARAEKVHKDTENFLKYEHKG-----------------LGNNNNFSRAKVSPTGPVRRNLGPQQPVHHAAPRP----------ATNAGPFGPPNARRHDGGPHP--------------SRNSERSGNYSSFRGSEFESASKFEYRDENQSRPVEATSATEELPVDSQLVLDELKDKNNYNPKVLDLKKAGSARFFVIKSYSEDDIHRSIKYEIWCSTDHGNKRLDDAFKERHEEGGNIMLFFSVNGSGHFCGMAQMMTPVDYNSTSSVWSQD-KWRGKFKVKWIYVKDVPNGTLRHIRLENNENKSVTNSRDTQEVPNDKGIEVLQILHSYNHSTSIFDDFFHYEKKQEEEVSSKRPPMHGPDGNNHAPAPLARSFNRQADDKDRDRDGRGGMSQKHFNSGGGAGFRNPGHRGGAGSGGSHNNYSEYRRGFDIHKSSSDYQFKDRDGPDFDRENDFGSHYGSNNRKNEYKHNNTNKARLKTRDRDFSTEQIKIGVRFKDTDKDKMRSNEYS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06390-1", "uniprot_id": "MRB1_YEAST", "id": "Q06390-1", "name": "Methylated RNA-binding protein 1", "aln": "---------------------------------------------------------------------------------------MNQIWSTGPPNFYFN-----------------------------SEWKENKRNDRTIEDSLRELDGLIHSLERTHIEVQTNPKLKN--------------------------------------------------------------DVTALNDINKKENKEEITHENYT-------------------------------------HQINSIP-----------------------------------------------------LTSSNLNRHFSFSRDYNQSDNSNNNYYREYLSKPRYLQQS------TKEQTFNEINKRKSAAIIPPWLNIPENSRFFVIKSSSLKHVKRSFYNGIWSSTHFGNKRLSEAYKKLNSGA-KVFLFFSINTSGRFCGVAEMVSDLKMDLDTSIWEDEQKYGKAFKVRWVIVRDINNRSLKRFLIPSNEMKPITHSRDTQEIPYSIGISIINLFKTQDS-----DIFSFLDETYE------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : ... :.: : . . . : : * : . : * .: : . : . . .::::. :. : .*.*:*** * ..::**: **.**..*****. *::. . : *:**:* **:***:*:* : :. : :.:*.:: *: *.*:*: *:*: * *::: : .** *.:*:******:* . . .::::: : . . : : ", "identical_positions": 51, "similar_positions": 94, "identity": "6.82%" }, { "cls_id": "homologset.agr.MGI:2444236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A666-1", "uniprot_id": "UBN2_RAT", "id": "D4A666-1", "name": "Ubinuclein-2", "aln": "MAEPRRVAFISLSPVRRREADFAGAEREP------PRLEPQPYREPARAEP------APRADAQPPARDKPLPQREVSRAEPPMALQREPPRPEPPP--PPLPLQTPPPRESASRAEPPPRPPKETVRLELVLKDPTDESCVEFSYPELLLCGEQRKK------LVHTEDPFTDEHKERQEVEMLAKKFEMKYGGKARKHR-KDRLQDLIDIGFGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFR--------------------------------QASDTEEDDFTDNQKHKPPKVPKIKDDDIEAKKRKRKE--EGEKEKKPRKKVPKQLGVVALNSHKSEKKKKR--YKDSLSLAAMIRKFQKEKDALKKE--STPKVPVIPSTSSLPKPPCAATTLG-DDIPDLSLNSADPD---LPIFVSTNEHELFQEAENALEMLDDFDFDR-------------LLDATSDGSPLSESGGENGNTTQPTFASQVVPKVVPTLPDGLPVLLEKRIEDLRVAAKLFDEEGRKKFFTQDMNNILLDIELQLQELGPVIRSGVYSHLEAFVPCNKETLVKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLFKYQEDCQARSQAKCAKLQADEEREKNGSDDDDDEKPGKRVIGPRKKFHWDDTIRTLLCNLVEIKLGCYELEPNKSQSAEDYLKSFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVIPASKPKVKEVMVKTLPVRSFPTMLKECSPKKDPKAPASVVASGGCPCTSSSTSIVASASSSSTPAQETICLDDSLDEDLSLPSASLDLVSEALAVINNGNKGPSVSSRLNVPTTKPRPGLREEKLASIMSKLPLATPKKLDSPQTAHSSSLIAGHTGPVPKKPQDLAHTGISSGLIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHASSS-QTHVSSS-QAQAAASSHALGTSEAQDASSLTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVVKLSNNPQLSCSSQLLKTSEKPLMYRLPLSTPSPGNGSQGSHPLVSRTAPSTTTSSNYLAKAMVSQISTQGFKSPFSMAASPKLAASPKPATSPKPLTSPKPSVSPKPSLSAKPSVSTKLISKSNPTPKPAVCPSSSSPNTLVAQSSHSTSNNPAHKQPSGMNISRQSPTLNLLPSNRTSGLPTTKTLQAPSKLTNSSSAGTVGKNSLSGIPVNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKPLSTPHRPTSASGSSVVTASVQSTAGASLLANASPLTLMTSPLSVTNQTVTPFGMLGGLVPVTMPFQFPLELLGFGTDTAGVTATS---GSTSAALHHGLTQNLLKSLQPG-TQHAATLPHSPLPTHLQQAFNDGGQSKGDTKLPRKPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WC1-1", "uniprot_id": "UBN2_MOUSE", "id": "Q80WC1-1", "name": "Ubinuclein-2", "aln": "MAEPRRVAFISLSPVRRREADFAGAEREP------PRLEPQPYREPARAEP------APRADAQPPARDKPLPQREVSRAEPPMALQREPPRPEPPP--PPLPLQTPPPRESASRAEPPPRPPKETVRLELVLKDPTDESCVEFSYPELLLCGEQRKK------LVHTEDPFTDEHKERQEVEMLAKKFEMKYGGKARKHR-KDRLQDLIDIGFGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFR--------------------------------QASDTEEDDFTDNQKHKPPKVPKIKEDDIEVKKRKRKE--EGEKEKKPRKKVPKQLGVVALNSHKSEKKKKR--YKDSLSLAAMIRKFQKEKDALKKE--STPKVPVTPSSSSLPKPPCVTTALG-DDIPDLGLNSADPD---LPIFVSTNEHELFQEAENALEMLDDFDFDR-------------LLDATSDGSPLSESGGENGNTTHPTFPSQVVPKVVPTLPEGLPVLLEKRIEDLRVAAKLFDEEGRKKFFTQDMNNILLDIELQLQELGPVIRSGVYSHLEAFVPCNKETLVKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLFKYQEDCQARSQAKCAKLQADEEREKNGSDDDDDEKPGKRVIGPRKKFHWDDTIRTLLCNLVEIKLGCYELEPNKSQSAEDYLKSFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVIPASKPKV-----------------KECSPKKDPKAPASVVASGGGPSTSSSTSIVASASSSSAPAQETICLDDSLDEDLSFPSASLDLVSEALAVINNGNKGPSVGSRLNVPTTKPRPGLREEKLASIMSKLPLATPKKLDSTQTAHSSSLIAGHTGPVPKKPQDLAHTGISSGLIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHASSSSQTHVSSS-QAQAAASSHALGTSEAQDASSLTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVVKLSNNPQLSCSSQLLKTSDKPLMYRLPLSTPSPGNGSQGPHPLVSRTAPSTTTSSNYLAKAMVSQISTQGFKSPFSMAASPKLAASPKPATSPKPLPSPKPSVSPKPSLSAKPSISTKQISKSNPAPKPAVCPSSSSPNTLVAQSSHSTSNNPVHKQPSGMNISRQSPTLNLLPSNRTSGLPTTKTLQAPSKLTNSSSTGTAGKNSLSGIPMNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKPLSTPHRPTSASGSSVVTASVQSTAGASLLANASPLTLMTSPLSVTNQTVTPFGMLGGLVPVTMPFQFPLELLGFGTDTAGVTATS---GSTSAALHHSLTQNLLKSLQPG-AQHAAALPHSPLPAHLQQAFNDGGQSKGDTKLPRKPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZU65-1", "uniprot_id": "UBN2_HUMAN", "id": "Q6ZU65-1", "name": "Ubinuclein-2", "aln": "MAEPRRVAFISLSPVRRREAEYPGPEREPEYPREPPRLEPQPYREPARAEPPAPREPAPRSDAQPPSREKPLPQREVSRAEPPMSLQREPPRPEPPPPFPPLPLQPPPPRESASRAEQPPRPPRETVRLELVLKDPTDESCVEFSYPELLLCGEQRKK------LIHTEDPFNDEHQERQEVEMLAKKFEMKYGGKPRKHR-KDRLQDLIDIGFGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFR--------------------------------QASDTEEDDITDNQKHKPPKVPKIKEDDIEMKKRKRKE--EGEKEKKPRKKVPKQLGVVALNSHKSEKKKKR--YKDSLSLAAMIRKFQKEKDALKKE--SNPKVPVTLSTPSLNKPPCAAAALG-NDVPDLNLSSGDPD---LPIFVSTNEHELFQEAENALEMLDDFDFDR-------------LLDAASDGSPLSESGGENGTTTQPTYTSQVMPKVVPTLPEGLPVLLEKRIEDLRVAAKLFDEEGRKKFFTQDMNNILLDIELQLQELGPVIRSGVYSHLEAFVPCNKETLVKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLFKYQEDCQARSQAKCAKLQTDEEREKNGSEEDDDEKPGKRVIGPRKKFHWDDTIRTLLCNLVEIKLGCYELEPNKSQSAEDYLKSFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVIPAPKPKVKEVMVKTLPLHSFPTMLKECSPKKDQKTPTSLVASVSGPPTSSSTAAIAAASSSSAPAQETICLDDSLDEDLSFHSPSLDLVSEALAVINNGNKGPPVGSRISMPTTKPRPGLREEKLASIMSKLPLATPKKLDSTQTTHSSSLIAGHTGPVPKKPQDLAHTGISSGLIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHTSSSSQTHVSSSSQAQIAASSHALGTSEAQDASSLTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVVKLSNNPQLSCSSSLIKTSDKPLMYRLPLSTPSPGNGSQGSHPLVSRTVPSTTTSSNYLAKAMVSQISTQGFKSPFSMAASPKLAASPKPATSPKPLPSPKPSASPKPSLSAKPSVSTKLISKSNPTPKPTVSPSSSSPNALVAQGSHSSTNSPVHKQPSGMNISRQSPTLNLLPSSRTSGLPPTKNLQAPSKLTNSSSTGTVGKNSLSGIAMNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKPLSTPHRPSTASGSSVVTASVQSTAGASLLANASPLTLMTSPLSVTNQNVTPFGMLGGLVPVTMPFQFPLEIFGFGTDTAGVTTTS---GSTSAAFHHSLTQNLLKGLQPGGAQHAATLSHSPLPAHLQQAFHDGGQSKGDTKLPRKSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3ISA2-1", "uniprot_id": "I3ISA2_DANRE", "id": "I3ISA2-1", "name": "", "aln": "MAEPRKVQFVTLSALAGG----PGADNRR------RRLEED--------------------------------------GAAEMSFDREGRMKMMGT-----GVTTAGDRGGLIGKRDSEEPKGKTVRLNLCLSEPSEQCSAEFNYSELIQSQQPKKNPPCSKSSLDPNDPFNDDEKERLQVEALAKKFESKYGNAGKKRR-KDRMQDLIDIGFGYDESDPFIDNSEAYDELVPASLTTKLGGFYINTGTLQFR--------------------------------AASESEGEDKVKDEK------PRIRDGEEPLMKRRKKKDVIGIEEKKPRKNKVAKQGVAGLSLHRPEKKKRKKLMKDSLCLAAMLRRFTREKEEIRKQDISSSHLGLTSAPNSNNLLQNSHLHIGHANHTDLSLADLTADPAMMSLLSSANESELQDIMRDLDFSSLDAAPQT-------------PPSCRENGQVGMGSSLGNKIGVGGLNRGQAGVVSFPTLPNGLPAPLIKRIEDLRAASRQFDQEGRKKFFTLDMNNILLDIELQVQEQPDHVRSEVYSHLEAFVPCNKEALLKRLKKLSLNIQDDSLRTPLLKLKLAVCSVMPEQIARYNMDCMAKVAAK----QQIEDGEKNGSEDDDEEKPGKRVMGPRKKFIWDDKLRTLLCNLVRVKLSCYQLEQC-SLSVEDYLKAFMENEVKPLWPKGWMQTRMLFKESRAVHGHLT-GLGKKRIVPTPKAAK-------------------MTDMVWTQRPAPGVGS-----TSASPALPASACRPSSPS-EPICLSDSLDEDLAAN--SLDSISQALALLSNAAKGLTPNNGIAASSAPSVPGS---------------------SSGVTHYSSPLSHSTLSAKMEP-----SGIPLGNMS-SISTSPSLSIS-----------SPSSSMRGDNFGMLKDGGALQRLSGTPTHRAG---------ISGMSTVQSAKPRPPPTASPLLPPQQRSYGTMGVKMVQTPPLVKNCANKPTTGGNTVVSQPRVNANPSQQSP----------PPPTTSSPSTLLAQVKTIPHN--QSNFITPMQATLTKSSHSSNSPIIKLTPRPPV-PTPPPSSSPSPSS---SPSLTHPRPQLIPTS----------HQFTPKSPAFRPPFTTQAAGVTSAVKSISGQASYSFAGGHKSASPPVGGASITNTTPMTAPLSAACKDGSPSPSAPLANHNQ-RQRQVGGASQVAKSSTSRASAMTLPSPPVSSHLSQGSPSS--GSNLLGSVPPSLPLG------------FGMLGGLVPVSLPFQFP-SLLNFSPTGPGVPSCSNLGSSPAPNSGYTLAQNLFKSLQPG--------SQVALPPHLQLAFSDANQSQGGDTK-RKSH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25992-1", "uniprot_id": "YEMA_DROME", "id": "P25992-1", "name": "yemanuclein", "aln": "MSKGGEHKRVTLTSIIQG----------------------------------------------------------------DAGFSRFGSN----------ILEPDAASAAPDNSSKPTTKTAKCIRIKLDLFETDSNKYPEFNYSRLLYLEKKKTKKLKQVSTTNGSASTDPFADNDDDVARIVKELEAKYGNSYATGRGKSKKDDYRDIGMGYDESDSFIDNTEAYDEIIPEEAETLEGGFYINCGALEFKNLTKKSYTTRTDAIIKMPERSRKRMVSSSSESSSSSSGDDDENDDGNNEEDDESDSEDDSEENDESDSEDDSESESLEDEDSAATAKSSSKYKDNHQAKRAKVIVTGKSKPSSSSLTSGKKPPTKPITTSSSSNSPRPSTVEISDTEDGQDPIQTQPSSQLQSLPQSQAQAQALKKVVKTTTVKDMLKAKRDSFLKSQSGTAAVKGVGNGELKCVSTDVSSSDSSDMESEHGRADRQAGQHGKDGQENLRTADTLLPTTLDADIVTAVNSFKEAVKSRDMCGKKFNLDVKLSPLLLRVYEAVLCTDRNERNMVFSHIEYQLQLPKYYMLRKGKQVRAKEEKRKSTIMLEKLRRAVAVVMPKAVANYETELRT--------------FAEQAAADVNSELPPK---MPRKKFQWTSELRHLLYDVYQARWTSYAFLAKRKESLEEFINWYLKEKVVELWPPGWMRLDELQREITRYKNAKLKAKEKPKAPPASASPK------------------------------------------------------------------------------------PVGVVSAPEQMPPASSYLKAVEDPRSRGN-----------------------SDTDSATSASSNSLKRKLKEMPKQTSKPPKKKVAKQVPLQP--------------------------------------------------------QLTPHPQFQLAPAATAAVSIPAISNNNNHLPHLDTLLSMPSTSAQAAALNAAAVAAASTVLDLASPSRK--------------IDLNTSNNFYNLITAASLAASGNPSPHSGDGQAKVIVGARPSPHVINLDDYQCTSDILQTSKQLAATTTVITAISKAAQTTSVARES-------------------SSESDGVEIVGVFPASKPQKKVQSKPKNKTQNRGRSSLGAVGQVNGSLGYSANNMYIYNSPRTLGPVYDLTDPHIMKTMSNLKEMEKQFIQAAFSPNSVKGASGG---------------MGSSAPSTPTRQ------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: . ::*:.: .:.* : . . . : :*::* * :. .: **.*..*: : :.: . . . .: :* :.*::* ***. . * *.: :* ***:****:*.****:*****::* . * ****** *:*:*: :*.: :* .: : . .:.. : :. . . :. . : . . *:.:: * *.. . ::: .. : .. *.. . : .* . .: : :: : * . . .. ... . . : . ** * . : . ::.:: * : * *:* : .:. :** : : *. *:**:* : * :::: *:: : :. * **: **. ***: : .*: : : ::.: : :.* * * ***** * . :* ** :: . : .* : . * *:::: ::: :* *** ***: * :* :. . * : *:. . .:.::. : . .. : * :. :: : : : : . :: . .* :: . .: . * . .. . : . . :: ... .**. . :. . * . ...: ..:.: : . . . .: :: : * . . : * . : .: : : :. .. . : . . : . : .. . .. . : . : . . .. :.. .* ", "identical_positions": 115, "similar_positions": 292, "identity": "8.14%" }, { "cls_id": "homologset.agr.MGI:2444240", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L9N7-1", "uniprot_id": "A0ABK0L9N7_RAT", "id": "A0ABK0L9N7-1", "name": "", "aln": "MSSAAKSQVLEETAPGCEEEPKGKTLFTWGSLFGHRSEKIVFTKGDGSPEESLLTVTITETTVIESDLGVWSSRALIYLTLWFFFSFCTLFLNKYILSLLEGEPSMLGAVQMLSTTLIGCVKIFVPCCLYQHKTRLSYPPNFIMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNILGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVALLIPAWTFFMDVPVIGGSGKSFSYSQDIVLLLLTDGALFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSIIVFGNKITSLSAIGTILVTVGVLLYNKARQYQQETMQSLVTATSQGPNDDTEPLVSQDSRQHH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C811-1", "uniprot_id": "S35E2_MOUSE", "id": "Q8C811-1", "name": "Solute carrier family 35 member E2A", "aln": "MSAAAKSQVPEEAAPGCEEEPKGKTLLTWGSLFGHRSEKIVFTKGDGSPEESLLTVTITETTVIESDLGVWSSRALIYLTLWFFFSFCTLFLNKYILSLLEGEPSMLGAVQMLSTTLIGCVKIFVPCCLYQHKTRLSYPPNFIMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNILGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVALLIPAWTFFMDIPVIGRSGKSFSYSQDIVLLLLTDGALFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSIIVFGNKITSLSAIGTILVTLGVLLYNKARQYQQETMQSLVTATSRNPEDDTEPLVPQDSRQHH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CK96-1", "uniprot_id": "S352B_HUMAN", "id": "P0CK96-1", "name": "Solute carrier family 35 member E2B", "aln": "MSSSVKTPALEELVPGSEEKPKGRSPLSWGSLFGHRSEKIVFAKSDGGTDENVLTVTITETTVIESDLGVWSSRALLYLTLWFFFSFCTLFLNKYILSLLGGEPSMLGAVQMLSTTVIGCVKTLVPCCLYQHKARLSYPPNFLMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNVLGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVAMLVPARVFFTDVPVIGRSGKSFSYNQDVVLLLLTDGVLFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSVIVFGNKITSLSAVGTALVTVGVLLYNKARQHQQEALQSLAAATGRAPDDTVEPLLPQDPRQHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CK97-1", "uniprot_id": "S35E2_HUMAN", "id": "P0CK97-1", "name": "Solute carrier family 35 member E2A", "aln": "MSSSVKTPALEELVPGSEEKPKGRSPLSWGSLFGHRSEKIVFAKSDGGTDENVLTVTITETTVIESDLGVWSSRALLYLTLWFFFSFCTLFLNKYILSLLGGEPSMLGAVQMLSTTVIGCVKTLVPCCLYQHKARLSYPPNFLMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGRPS-------------------------------------------------DREEREELQLQPGRGAAASDRRSP-------VPPSERHG---------------------------VRPHGENLPGDFQVPQALHR-------------------------VALSMALP--------------------------CPMLPAS-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::.*: . ** .**.**:***:: ::**************:*.**..:*.:***********************:*********************** ***************:***** :*********:********:***************************************************** *: . . :** .*** * :* * *: * *.*..:::: *::.: * *::. . ", "identical_positions": 182, "similar_positions": 46, "identity": "44.94%" }, { "cls_id": "homologset.agr.MGI:2444243", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FMK8-1", "uniprot_id": "F7FMK8_RAT", "id": "F7FMK8-1", "name": "Mitogen-activated protein kinase kinase kinase 13", "aln": "------MANPQEHLSCSSLPHLP---LTENKIS-GGRNELAAMGNHPSPKFPEDSQERVV----AIQSELTEITG--SPV----------------STTVLTSVSEDS---RSQFENSVLQLREQDESEVTVSPGNS------------------NTVDGENTNGPEDIKIQFSRSGSGSGGFLEGLFGCLRPVWNIIGKAYSTDYKLQQQ-DTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEVAIKKVREQNETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLDIASADVLATPQETYFKSQAEWREEVKKHFEKIKSEGTCIHRLDEELIRRRREELRHALDIREHYERKLERANNLYMELSAIMLQLEMREKELLKREQAVEKKYPGTYKRHPVRPIIHPNAMEKLMKRKV-VSHKAGVQT-KRPDLLRSEGIPSTEAVPTASPLSGSPKMSTGSSR-SRYRSKPRHRRGNSRGSHSDFAAILKTQPAQENSPHPTYLQHTQAQCPSAYQHNLPQQQ---VPPPLPQSRHPRLNAHGQDIATCANNLR----YFGPAAALRSPLSNHAQRQMPGSSPDLISTAMAADC-WRNSELDQDQVGPWGCCQAEPYDPCFQCRP----EHSGSLDVPTTEPVGRSPDPSSSPAHN-PLSGNAQGSERTEANGFNGCQS----GISHQFTPPLLPQ----KPRPLQKAFPPCPPQSGDDSSEEE-GEVDSEVEFPRRQRPHRCISSYQSYSTFSSENFSVSDGEEGNTSDHSNSPDESANRRQDRLAETLDDLLSQTPEAPIEISSHSDGLSDKECAVRRVKTQMSLGKLCAEERGYENPVQFADSDRDSSEGDCSDATVRTSKNYSSATW---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1HKZ5-1", "uniprot_id": "M3K13_MOUSE", "id": "Q1HKZ5-1", "name": "Mitogen-activated protein kinase kinase kinase 13", "aln": "------MANPQEHLSCSSLPHLP---LTENKTS-GGRNELAAMGNHPSPKLPEDPQERG-----AIQSELMEITG--SPI----------------STTVLTSVSEDS---RGQFENSVLQLREQDESEMTLSLGNS------------------NTVDGENTNGPEDIKIQFSRSGSGSGGFLEGLFGCLRPVWNIIGKAYSTDYKLQQQ-DTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEVAIKKVREQNETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLDIASADVLATPQETYFKSQAEWREEVKKHFEKIKSEGTCIHRLDEELIRRRREELRHALDIREHYERKLERANNLYMELSAIMLQLEMREKELLKREQAVEKKYPGTYKRHPVRPIIHPNAMEKLMKRKG-VPHKAGVQT-KRPDLLRSEGIPSTEAVPTASPLSGSPKMSTASSR-SRYRSKPRHRRGNSRGSHSDFAAILKTQPAQENSPHPTYMHHTQAQCASVHQHNPLQQQYQQIPPAQPQSRHPRLNAHGQDIATCANNLR----YFGPAAALRSPLSNHAQRQMPGSSPDLISTAMAAD--WRNSELDQDQVGPWGCCQAEPYDPCFQCRP----EHSGSLDVPTTEPVGRSPDLSSSPAHN-PLSGNAQGSERTGANGFSGCQS----GISHQFTPPMLPQ----KTRPLQK--------SGDDSSEEE-GEVDSEVEFPRRQRPHRCISSYQSYSTFSSENFSVSDGEEGNTSDHSNSPDESANRRQDRLAETLDDLLSQTPEAPIEISSHSDGLSDKECAVRRVKTQMSLGKLCAEERGYENPVQFGDSDCDSSEGECSDATVRTSKNYSSATW---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43283-1", "uniprot_id": "M3K13_HUMAN", "id": "O43283-1", "name": "Mitogen-activated protein kinase kinase kinase 13", "aln": "------MANFQEHLSCSSSPHLP---FSESKTFNGLQDELTAMGNHPSPKLLEDQQEKG-----MVRTELIESVH--SPV----------------TTTVLTSVSEDS---RDQFENSVLQLREHDESETAVSQGNS------------------NTVDGESTSGTEDIKIQFSRSGSGSGGFLEGLFGCLRPVWNIIGKAYSTDYKLQQQ-DTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEVAIKKVREQNETDIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLDIASADVLATPQETYFKSQAEWREEVKKHFEKIKSEGTCIHRLDEELIRRRREELRHALDIREHYERKLERANNLYMELSAIMLQLEMREKELIKREQAVEKKYPGTYKRHPVRPIIHPNAMEKLMKRKG-VPHKSGMQT-KRPDLLRSEGIPTTEVAPTASPLSGSPKMSTSSSK-SRYRSKPRHRRGNSRGSHSDFAAILKNQPAQENSPHPTYLHQAQSQYPSLHHHNSLQQQYQQPPPAMSQSHHPRLNMHGQDIATCANNLR----YFGPAAALRSPLSNHAQRQLPGSSPDLISTAMAADC-WRSSEPDKGQAGPWGCCQADAYDPCLQCRP----EQYGSLDIPSAEPVGRSPDLSKSPAHN-PLLENAQSSEKTEENEFSGCRSESSLGTSHLGTPPALPR----KTRPLQK--------SGDDSSEEEEGEVDSEVEFPRRQRPHRCISSCQSYSTFSSENFSVSDGEEGNTSDHSNSPDELADKLEDRLAEKLDDLLSQTPEIPIDISSHSDGLSDKECAVRRVKTQMSLGKLCVEERGYENPMQFEESDCDSSDGECSDATVRTNKHYSSATW---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PA62-1", "uniprot_id": "A0A8M9PA62_DANRE", "id": "A0A8M9PA62-1", "name": "Mitogen-activated protein kinase kinase kinase", "aln": "MHTHSTMGSSPEVLSWTSCPSLLVGKLKEELKLTVVGDSIKKPNNNISPQALLPPAPPPPPPPPQIITDLAPPTT--LPMPLHHLQLPVRDEEPGGTSPPCTALSEDSTREQGHFENSVLQLQEQEDAETPGSCGQGGCGSGGEEKNEENGCPMEHSGDDTHHHPHDDIKLHFHRAGTGSGGFLEGLFGCLRPVWNIIGKTYSTEYKLQQQVEMWEVPFEEISELQWLGSGAQGAVFLGKFRSEEVAIKKVREQKETDIKHLRKLKHPNIISFKGVCTQAPCYCIIMEYCAQGQLYEVLRAGRKITPCLLVDWASGIASGMNYLHLHKIIHRDLKSPNVLVTQNDSVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQGKPRNRPSFRQILLHLDIASADVLGTPQETYFKCQTEWREEVKKHFEKIKSEGTCIHRLDEELIRRRRDELRHALDIREHYERKLERANNLYMELSAIMLQLEVREKELLKREQAVEKKYPGTYKRHLVRPIVRPNAVEKLIKKKSSMNHKPGTQQPKRPDLLRSDGIPSVEPLPAPSPLSGSPKVSTPPGK-TRYRSKPRHRRANSKGSHNEFPGALKPNSGPPEEQQP------------LQEQNYLQNHP--LPPPEP----PLAKTRENAVATCANNLR----YFGPAAALRSPQTDHLQRRLSGSSPDLISTAVDADSRLRRSSIPPGPAPLCPCCQAHPFPGCKHCQQ----TPAAPSHPQLPHYSLLSTNDGTPPASKRNLEPTAEGQDKEEK--------------------PALLH----TLRPLRK--------TGDESSEEEEGEVDSEVEFPRRQRPHRCMSSFQSYSTFSSENLSVSDGEEGNTSDHSHSG--PLEQLSGSQEEHLDELLSHTPEIPIDISTQSDGLSDKECAVRRVKTQISLGKLCADEHSYENPLHFGDSDCDTSDAECSDATIRNKPPGAPSSW---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW24-1", "uniprot_id": "Q9VW24_DROME", "id": "Q9VW24-1", "name": "Mitogen-activated protein kinase kinase kinase", "aln": "------MQPFSDSLSKSRDDLVT----AASRQQQQLHGRRRHHGSSPNLSLDQTDNLRRS------MACLQDEFGHLG--------------------IAATDLPFKS----SDLDSPPRLQHHNNYAEITDSSAEN-------------------TCQQRWPPHVGGAGAAFGHPDKPIG-WMYGLLGCMKPVLSFIGKTGVIEVKSQRS-EDWQIPFESITELEWLGSGAQGAVFSGRLKNETVAVKKVKELKETDIKHLRKLDHENIIKFKGVCTQSPVFCIIMEFCPYGPLQNILKEEQVMLPSRLVSWSKQIALGMQYLHSHKIIHRDLKSPNILISTNEVVKISDFGTSREWNEISTKMSFAGTVAWMAPEVIRNEPCSEKVDIWSYGVVLWEMLTCEIPYKDVDSSAIIWGVGNNSLKLLVPSTCPEGFKLLVKLCWKSKPRNRPSFRQILSHLDIAGPELLRKTEKQYFETQKSWKEEVRSHLKEITQNGTNIHKYEQDLIKRRTAEWRHAQDIRMVYEDKLQKTNQLFFELSECMSQLQEKEKEIAERERKLPGSGYKPNRRFGNTIRKMQHYRRRLNPAPAAIQQQSTTPDPETTPESPVKCMLYAQLDSNCQPKSYLANIIPSSGLGAPMPNKNKKVFRHRRNASGSFGAPPKYSPTRDRRYQSEPENRKVQLVERQTQTDAMDVSETDISPSAEAPRSQPIDVPVPNHRQLPLQLQRVQKIAQAQARARSGSTSSAAGAVNPACPSNGNSLSTSELTYQDACSSPDQLIDDVMNSNERLDMTECCSDNENLERLGRKVIEFINENRLSIQSNTNSVSNADNGNGGASPLELRESGNSPCLSRCSSTHSKRRKHPLGDNPNGSSIG----------NANGESHEQDSWSDEEGETTDYKYALRRRSIGRQPIARGMRPRRSYKAPLSQKIAIHKRNVVIVSDEEENTSEYSHSPSSQHSTLESNTDIADMKKTQATSTSSNSYSEPEDDSSDSSDEEQGNRPTEAKAEGPALPMGAVRSSDIISIPTFEADGAVNMV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ** : : . . .. . . : * * :. .* ..::.. :.:: :* . * .:. : : . * :... * :: **:**::** .:***: : * *:. : *::***.*:**:*********** *::: * **:***:* :**********.* *** *******:* :*****:*. * * ::*: : : * **.*:. ** **:*** ************:*:: .: *********:* .: ********************** ********:******:** *****************.***:* ******:***:*:* *:.********** * *****..::* ..:: **: * .*:***:.*:::*..:** **: :::**:** * *** *** ** **:::*:*::*** * **: :***: :**: : . . :*. : .:* : ::. : . . : .: . .* * .:: . .. : .* :: : :.: ..* . * .. . :. . : : .*. . . :*: . * ** :. : :.*. .: :: : : . . . * . . * : .. .. : . . . * . . .*:. .::. .: :.*. : :*.:. : ... : .: : .: : :. . . . * * :*: .. : . .: :.: . .. . :*:. . . :. . . *. : : .: ", "identical_positions": 265, "similar_positions": 266, "identity": "25.29%" }, { "cls_id": "homologset.agr.MGI:2444248", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LRI5-1", "uniprot_id": "F1LRI5_RAT", "id": "F1LRI5-1", "name": "Stalled ribosome sensor GCN1", "aln": "MAADTQVSETLKRFAVKVTTASVKERREILSELGRCIAGKDLPEGAVKGLCKLFCLTLHRYRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGVGSKACVPSKSSGSAALLALTWTCLLVRIVFPLKAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLWKENPGLVEQYFSAILSLEPNQNYAGMLGLLVQFCTNHKEMDVVNQHKSTLLEFYVKHILMSKAKPPKYLLDNCAPLLRFMSHSEFKDLILPTIQKSLLR---SPENVIETISSLLASVTLDLSQYALDIVKGLANQLKSNSPRLMDEAVLALRNLSRQCSDSSATEALTKHLFAILGGSEGKLTIIAQKMSVLSGIGSLSHHGVSGPSGQVLNGCVAELFIPFLQQEVHEGTLVHAVSVLALWCNRFTTEVPKKLTDWFKKVFSLKTSTSAVRHAYLQCMLASFRGDTLLQALDFLPLLMQTVEKAASQSTQVPTVTEGVAAALLVSKLSVADSQAEAKLSNFWQLVVDEKKQIFTSEKFLLLASEEALCTVLHLTERLFLDHAHRLTNSRVQQYYRVLVAVLLSRTWHVRRQAQQTVRKLLSSLGGIKLANGLLEELKTVLNSHKVLPLETLVTDAGEVMETGKTYVPPRVLQEALCVISGVPGLKGDITSTEQLAQEMLIISHHPSLVAVQSGLWPALLTR-MKIDPEAFITRHLDQIIPRITTQSPLNQSSMNAMGSLSILSPDRVLPQLISSITASVQNPALCLVTREEFAVMQTPAGELFDKSIIQSAQQDSIKKANMKRENK-AYSFKEQIIELELKEEIKKKK---GIKEEVQLTSKQKEMLQAQMDKEAQIRRRLQELDGELEAALGLLDAIMTRN---PRGLTQYIPVLVDAFLPLLKSPLAAPRVKGP--FLSLAACVMPPRLKTLGTLVSHVTLRLLKPECALDQSWCQEELPVAVRRAVSLLHTHTIPSRVGKGEPDAAPLSAPAFSLIFPMLKMVLTEMPYHSEEEEEQMAQILQILTVHAQLRASPDTPPERVDENGPELLPRVAMLRLLTWVIGTGSPRLQVLASDTLTALCASSSGEDGCAFAEQEEVDVLLAALQSPCASVRETALRGLMELH-LVLPAPDTDEKNG--LNLLRRLWVVKFDKEEEIRKLAERLWTTMGLDLQSDLCSLLIDDVIYHEAAVRQAGAEALSQ----AVARYQRQAAEVMGRLMEIYQEKLYRPPPVLDALGRVISESPPDQ--WEARCGLALALNKLSQYLDSSQ--VKPLFQFFVP-DALNDRNPDVRKCMLDAALATLNAHGKENVNSLLPVFEEFLKDAPNDASYDAVRQSVVVLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAVKEDAGGMIQRLMQQLLE-SDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGALFAFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIVQRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIVATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRAGQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASEDDNFGTAQSNKAIITALGVDRRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQ-KSDERQGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQALEDILPFLLKQLDDEE--VSEFALDGLKQVMAVKSRVVLPYLVPKLTTPPVNTR---VLAFLSSVAGDALTRHLGVILPAVMLALKEKLGTPDEQ-LEMANCQAVILSVEDDTGHRIIIEDLLEATRSPEVGMRQAAAIILNMYCSRSKADYTSHLRSLVSGLIRLFNDSSPVVLGESWDALNAITKKLDAGNQLALIEEFHKEIRYIGNECRGEHVPGFCLPKKGVTSILPVLREGVLTGSPEQKEEAAKALGLVIRLTSADALRPSVVSITGPLIRILGDRFSWSVKAALLETLSLLLGKVGIALKPFLPQLQTTFTKALQDS-NRGVRLKAADALGKLISIHIKVDPLFTELLNGIRVVEDPGIRDTMLQALRFVIQGAGAKVDAAIRKNIVSLLLGMLGHDEDNTRISSAGCLGELCAFLTEEELNTVLQQCLLADVSGIDWMVRHGRSLALSVAVNVAPSRLCTGKYSNEVQDMVLSNAVADRIPIAVSGIRGMGFLMKYHIETGGGQLPPRLSTLLIKCLQNPSSDIR-LVAEKMIWWANKEPRPALEPQAIKPILKALLDNTKDKNTVVRAYSEQAIVN---LLKLRQGEELLQSLSKILDVASLEALNECSRRSLKKLACQADS-------------VEQVDDTILT--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PVA8-1", "uniprot_id": "GCN1_MOUSE", "id": "E9PVA8-1", "name": "Stalled ribosome sensor GCN1", "aln": "MAADTQVSETLKRFAVKVTTASVKERREILSELGRCIAGKDLPEGAVKGLCKLFCLTLHRYRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGVGSKACVPSKSSGSAALLALTWTCLLVRIVFPLKAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLWKENPGLVEQYFSAILSLEPSQNYAAMLGLLVQFCTNHKEMDAVSQHKSTLLEFYVKNILMSKAKPPKYLLDNCAPLLRFMSHSEFKDLILPTIQKSLLR---SPENVIETISSLLASVTLDLSQYALDIVKGLANQLKSNSPRLMDEAVLALRNLARQCSDSSATEALTKHLFAILGGSEGKLTIIAQKMSVLSGIGSLSHHVVSGPSGQVLNGCVAELFIPFLQQEVHEGTLVHAVSILALWCNRFTTEVPKKLTDWFKKVFSLKTSTSAVRHAYLQCMLASFRGDTLLQALDFLPLLMQTVEKAASQGTQVPTVTEGVAAALLLSKLSVADAQAEAKLSGFWQLVVDEKRQTFTSEKFLLLASEDALCTVLRLTERLFLDHPHRLTNSKVQQYYRVLVAVLLSRTWHVRRQAQQTVRKLLSSLGGVKLANGLLDELKTVLNSHKVLPLEALVTDAGEVTEMGKTYVPPRVLQEALCVISGVPGLKGDIPSTEQLAQEMLIISHHPSLVAVQSGLWPALLTR-MKIDPDAFITRHLDQIIPRITTQSPLNQSSMNAMGSLSVLSPDRVLPQLISTITASVQNPALCLVTREEFSIMQTPAGELFDKSIIQSAQQDSIKKANMKRENK-AYSFKEQIIEMELKEEIKKKK---GIKEEVQLTSKQKEMLQAQMDKEAQIRRRLQELDGELEAALGLLDAIMARN---PCGLIQYIPVLVDAFLPLLKSPLAAPRVKGP--FLSLAACVMPPRLKTLGTLVSHVTLRLLKPECALDKSWCQEELPVAVRRAVSLLHTHTIPSRVGKGEPDAAPLSAPAFSLVFPMLKMVLTEMPYHSEEEEEQMAQILQILTVHAQLRASPDTPPERVDENGPELLPRVAMLRLLTWVIGTGSPRLQVLASDTLTALCASSSGEDGCAFAEQEEVDVLLAALQSPCASVRETALRGLMELR-LVLPSPDTDEKSG--LSLLRRLWVIKFDKEDEIRKLAERLWSTMGLDLQSDLCSLLIDDVIYHEAAVRQAGAEALSQ----AVARYQRQAAEVMGRLMEIYQEKLYRPPPVLDALGRVISESPPDQ--WEARCGLALALNKLSQYLDSSQ--VKPLFQFFVP-DALNDRNPDVRKCMLDAALATLNAHGKENVNSLLPVFEEFLKDAPNDASYDAVRQSVVVLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAVKEDAGGMIQRLMQQLLE-SDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGALFAFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIVQRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIVATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRAGQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASEDDNFGTAQSNKAIITALGVDRRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQ-KSDERQGVCIGLSEIMKSTSRDAVLFFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQALEDILPFLLKQLDDEE--VSEFALDGLKQVMAVKSRVVLPYLVPKLTTPPVNTR---VLAFLSSVAGDALTRHLGVILPAVMLALKEKLGTPDEQ-LEMANCQAVILSVEDDTGHRIIIEDLLEATRSPEVGMRQAAAIILNMYCSRSKADYSSHLRSLVSGLIRLFNDSSPVVLEESWDALNAITKKLDAGNQLALIEELHKEIRFIGNECKGEHVPGFCLPKRGVTSILPVLREGVLTGSPEQKEEAAKGLGLVIRLTSADALRPSVVSITGPLIRILGDRFNWTVKAALLETLSLLLGKVGIALKPFLPQLQTTFTKALQDS-NRGVRLKAADALGKLISIHVKVDPLFTELLNGIRAVEDPGIRDTMLQALRFVIQGAGSKVDAAIRKNLVSLLLSMLGHDEDNTRISTAGCLGELCAFLTDEELNTVLQQCLLADVSGIDWMVRHGRSLALSVAVNVAPSRLCAGRYSNEVQDMILSNAVADRIPIAMSGIRGMGFLMKYHIETGSGQLPPRLSSLLIKCLQNPCSDIR-LVAEKMIWWANKEPRPPLEPQTIKPILKALLDNTKDKNTVVRAYSDQAIVN---LLKMRRGEELLQSLSKILDVASLEALNECSRRSLRKLACQADS-------------VEQVDDTILT--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92616-1", "uniprot_id": "GCN1_HUMAN", "id": "Q92616-1", "name": "Stalled ribosome sensor GCN1", "aln": "MAADTQVSETLKRFAGKVTTASVKERREILSELGKCVAGKDLPEGAVKGLCKLFCLTLHRYRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGIGSKAGVPSKSSGSAALLALTWTCLLVRIVFPSRAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLWKENPGLVEQYLSAILSLEPNQNYAGMLGLLVQFCTSHKEMDVVSQHKSALLDFYMKNILMSKVKPPKYLLDSCAPLLRYLSHSEFKDLILPTIQKSLLR---SPENVIETISSLLASVTLDLSQYAMDIVKGLAGHLKSNSPRLMDEAVLALRNLARQCSDSSAMESLTKHLFAILGGSEGKLTVVAQKMSVLSGIGSVSHHVVSGPSSQVLNGIVAELFIPFLQQEVHEGTLVHAVSVLALWCNRFTMEVPKKLTEWFKKAFSLKTSTSAVRHAYLQCMLASYRGDTLLQALDLLPLLIQTVEKAASQSTQVPTITEGVAAALLLLKLSVADSQAEAKLSSFWQLIVDEKKQVFTSEKFLVMASEDALCTVLHLTERLFLDHPHRLTGNKVQQYHRALVAVLLSRTWHVRRQAQQTVRKLLSSLGGFKLAHGLLEELKTVLSSHKVLPLEALVTDAGEVTEAGKAYVPPRVLQEALCVISGVPGLKGDVTDTEQLAQEMLIISHHPSLVAVQSGLWPALLAR-MKIDPEAFITRHLDQIIPRMTTQSPLNQSSMNAMGSLSVLSPDRVLPQLISTITASVQNPALRLVTREEFAIMQTPAGELYDKSIIQSAQQDSIKKANMKRENK-AYSFKEQIIELELKEEIKKKK---GIKEEVQLTSKQKEMLQAQLDREAQVRRRLQELDGELEAALGLLDIILAKN---PSGLTQYIPVLVDSFLPLLKSPLAAPRIKNP--FLSLAACVMPSRLKALGTLVSHVTLRLLKPECVLDKSWCQEELSVAVKRAVMLLHTHTITSRVGKGEPGAAPLSAPAFSLVFPFLKMVLTEMPHHSEEEEEWMAQILQILTVQAQLRASPNTPPGRVDENGPELLPRVAMLRLLTWVIGTGSPRLQVLASDTLTTLCASSSGDDGCAFAEQEEVDVLLCALQSPCASVRETVLRGLMELH-MVLPAPDTDEKNG--LNLLRRLWVVKFDKEEEIRKLAERLWSMMGLDLQPDLCSLLIDDVIYHEAAVRQAGAEALSQ----AVARYQRQAAEVMGRLMEIYQEKLYRPPPVLDALGRVISESPPDQ--WEARCGLALALNKLSQYLDSSQ--VKPLFQFFVP-DALNDRHPDVRKCMLDAALATLNTHGKENVNSLLPVFEEFLKNAPNDASYDAVRQSVVVLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAIKEDAGGMIQRLMQQLLE-SDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGALFAFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQQALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPIVQRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIVATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRAGQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFHISGVTGKMTTETASEDDNFGTAQSNKAIITALGVERRNRVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQ-KSDERQGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQALEDILPFLLKQLDDEE--VSEFALDGLKQVMAIKSRVVLPYLVPKLTTPPVNTR---VLAFLSSVAGDALTRHLGVILPAVMLALKEKLGTPDEQ-LEMANCQAVILSVEDDTGHRIIIEDLLEATRSPEVGMRQAAAIILNIYCSRSKADYTSHLRSLVSGLIRLFNDSSPVVLEESWDALNAITKKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCLPKKGVTSILPVLREGVLTGSPEQKEEAAKALGLVIRLTSADALRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIALKPFLPQLQTTFTKALQDS-NRGVRLKAADALGKLISIHIKVDPLFTELLNGIRAMEDPGVRDTMLQALRFVIQGAGAKVDAVIRKNIVSLLLSMLGHDEDNTRISSAGCLGELCAFLTEEELSAVLQQCLLADVSGIDWMVRHGRSLALSVAVNVAPGRLCAGRYSSDVQEMILSSATADRIPIAVSGVRGMGFLMRHHIETGGGQLPAKLSSLFVKCLQNPSSDIR-LVAEKMIWWANKDPLPPLDPQAIKPILKALLDNTKDKNTVVRAYSDQAIVN---LLKMRQGEEVFQSLSKILDVASLEVLNEVNRRSLKKLASQADS-------------TEQVDDTILT--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7PLL6-1", "uniprot_id": "Q7PLL6_DROME", "id": "Q7PLL6-1", "name": "", "aln": "-MVDEQLSAALRDLPGRVLNVPVEERQHLFQNVSSVLKNSGINSTIIRGICKVIGTTITKYKDPTSQRIVRDLIVDLVTIHHDLTIEHMLNVFKAFIYKEFASVSPQKSCKLAVIALGWISIIQKQAQ-RESNIFKTEKKKLIEYQTLLYQITVISPNQRVTDARTKILYDLWN-NTEIFNETMDTLFQMESTSNVTIFCMAMFQFKYKNCNALKLNQYTEKLSEYFVKSMISCKHKPDKSFIIACSPLLKSLTDAEFDSYIYPSLQRSILR---SPENTLQSIGLIFNMLNFDCSRYAQKVGIVLIKNLYSKGDIARQESLESLKLLSTKCSNWIIVKELLERIFSVLNGSDGKINVIEYRINILQGAGNLSFNNIDQDHMPNILNEAVTLFSKALECETQEKVICCTLEMFGLWTQKFIHNLPDVVINIFTSGMRLKTTNQIIRQSYLEWLLLSIQNAEVNNHISIIQDLISFYTKALQNSSQSCYLSEAACIACILLILEKPS----ENYNFFWTTVFDMKKLIFYNEKFTTTAPIPTLCNISLMARILINSYPEKIKG-KLEPLARTLVSNLCCNSVKVRVYTAKQVKQIINSSSGIEFVKLALCEFGKRIN------LVNIETDGEPLIDQFGTSN--QVYVDALLTLTSIKHIT--YEDSVDVAIDLLLISHHPAIVSNEPYLWETTIQKHLNLDAKNVILAKTNEIVNEYIDNYIASAQYENTISALIRICPNLIVPTVVNNLKNYLSNFSNYNVSNEEYLIFLTPDGELFDKSVIPHIDS-QYETVRLKRENK-VYSYKEQLEEIQLRREIDDKREKEGKLKTIRYTQKQEEQIKNQMEKELHIKLRITLLYEKLISKISLLKASCSGN---GEQMAQHFYSLLDGILNASKSPLCAEVLTDL--YIFLHNLCFTFQPK-LGRAIALATIKLQSPSCVLKKEFEAFNVNQAINDIIIDLDNHVKSN----------YLDSPSFSYAFEFLKRALLLLNTDS--DFDLISKGIQILALHTSAGVCCK----------PQFMPRFGMFKMLLDLLKNNN-KLWAQTSAAILQVAKCSNG-DNCSSPDNHIISIFLQALQHCSDAVRKVALQSLKIMVNGIVNHIKVDNSLE--KVIINRFWVAKHDPEEENRELALFLWNTAKFPLPG--YVDIINDITHSETCIQKSASESLIP----LLAGDEVLKKCVIKKLFSIYKAKLSLLPPVLDQFDREI-EPAIDQ--WKPRRGIAIAFSTIAFLLSIED--INDIMNFMVS-QGLGDREDVVHKEMLATALKIVDLHGNKAIENLLPVFEDFLDKAPKSQSYDNIRQAVVILMGSLARHLEKDDKRIDPIVKRLITSLSTPSQQVQEAVSNCLPHLMPSVKDEAPSMIKKLLHSLAK-SEKYGERRGAAYGIAGIVKGLGILSLKQLDIMSKLTAFIQDKKNYRSREGALFAFEVLCSTLGRLFEPYIVHVLPHLLQCFGDPSQYVRQAADDTAKVVMRKLSAHGVKLVLPSLLEALDEDSWRTKTASVELLGAMAFCAPKQLSSCLPSIVPKLIQVLGDSHTKVQESGGEALKVIGSVIKNPEIQAIVPVLLDALEDPSNNTSTCLQSLLKTKFIHFIDAPSLALIMPVVQRAFMDRSTETRKMAAQIIGNMYSLTDQKDLAPYLPSIIPGLKSSLLDPVPEVRAVSARALGAMVKGMGESSFENLLPWLMETLTSESSSVDRSGAAQGLSEVVGGLGVEKMHKLMPEIISTAERVDIAAHVKDGYIMMFIYMPGAFQEEFTPYIGQIINPILKALADESEFVRDTALKAGQRIVNLYAETAVALLLPELEKGLFDDNWRIRYSSVQLLGDLLYRISGVSGKMTTETASEDDNFGTEHSHTAIIHFLGDERRNRVLSGLYMGRSDVSLMVRQAALHVWKVVVTNTPRTLREILPTLFGLLLGCLASTSYDKRQVAARTLGDLVRKLGERVLPEIIPILENGLNSD-HPDQRQGVCIGLSEIMGSTSKEMVLTFIDSLVPTVRKALCDPLPEVREAAAKTFESLHSTVGSRALDEILPFMLQGLSDADPFVAENTLDGLRQVMSIKSKVVLPYLVPQLTSPPVNTK---ALSILVSVAGEALIKYLPKILSSLLEALSDAYGYPNEP-QENEYCQTVILSVTDETGIRTIMDTLLISANSSDLCTRKSAASLLSAFCIHSPGNYYEYIPQLLRCLLKLLVESDKDILQKSWEALNAVIKGMNAAQQICHVSDVRQAVRFAASELEGTELPGFCLP-KGITPLLPVFREAILNGLPEEKENAAQGLGEVIFLTNAKSLQPSVVHITGPLIRILGDRFNAAVKAAVLETLSILLHKVGVMLKQFLPQLQTTFLKALHDQ-NRNVRMKAGKALSELVAIHSRAEPLFNEIHNGIKNSDDSSVRETMLHALRSIVSRSGDKMSEPIKKQIYVTLLSMIGHHEDATRSAVGGCLGAILKYIASGHVYDLFNNIILTNNT-DDLIVKHGHTIVLFVALKECPTEVLVLDLPEKITSYVLINILSEKVPIASNAVRAATYLLDYYLVN-QNEPPIKIVMALSRAMNHSSNDVKQLVAQSCTYLSKNLAANQSSIDVLKYLVPMLVNGTKEKNGYVKSNSELALIS---ILRLRSDDTSFLKISGLLESGARDSLNDVVLKVLKRTSSQSIIK------------EEELDDTLQS--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33892-1", "uniprot_id": "GCN1_YEAST", "id": "P33892-1", "name": "eIF-2-alpha kinase activator GCN1", "aln": "MTAILNWEDISPVLEKGTRESHVSKRVPFLQDISQLVRQETLEKPQLSEIAFVLLNTFTIYEDNRSKSLVTSILLDILNLEPCLLEN-----FIRFISDVVISNPATKAVADYLNLLDWINSFLIFVSHNSNLFEEYIPKLLVAHSYATFGVETILDNQEEGKKSQDKQNQHRKRIRYCIFQTTVKAFLKCLKDNDDSISFMKISIKT------VLESYSKLKITSVGVVMIMGALTQAALQLLSRQPALHSVLKENSAEKYCEYLGKEVFLGKNPPSSFCLEIGLKPFLKEFVSQELFIKFFIPNIEKAVLRSPEVGFSILSELYAGVSPEKVNLLNAFASSKLINQYFSSFKSSKEVVRSVSLQSMIILLRKISNTDTTLEDLTKLIDEIFKNIKSNLNAD--YKSLISKILIEIPLTHYEVSEKICKGLSPYIGKEGNEAALTLMLNAFFVHYFSLGKPIEDLDKIISAGFADKKPALKKCWFAAFLNNSNAASEEVILNFIDG--------CLEFVKDSIIHYQTHGHACILASIEFTNKILALDNTELNDRVMQLIETLPENSSIGDAILTAALSTELSIENRIHAVNLLQELFYKKPEFIGFSVIDAIERRMRVQELIPQQNTS---------------FKYVTSVLLAITSELPDKEASIKVLINALVIAQWNIFNIKNG--WAGLVLR-ARLDPAEVVKEHASVIMEKILEITGSCEWIDTIYGACGLQAAAYAAFIQPNEFTPILCKTIEADLTADDFSRLSEEDFEIFAGEEGVLVVDVLEESMNKKLSNKNSKEYETLMWEQKIRKEQAKKN-------VKKLSKEEQELVNEQLAKESAVRSHVSEISTRLKRGIRLVSELSKAACLVQNGIATWFPLAVTKLLYLCSEPNISKLTEDVNNVFLQLSQNVSERLGNIRLFLGLATLRVHN-ANGISQDYLQEPLVELLTRVLFRIKFVSNQA----------AIDSISLTYILPLLINVLEKGKAIALKNADKPVVKAEFVEEDEEE---------------EHLLLAMEIISVHAEAFEDPSIPRISIVEVLLSLLSLPSKAKIAKDCFNALCQSISVAPNQEDLDMILSNLLSPNQFVRSTILETLDNEFELEPFMKYSPEVFICRFDSDPSNREIADFIWEFNKFVVNDELLKSLFPLFNQDDSGLRLFAANAYAFGAVSLFTSEENSSKDYLNDLLNFYKEKAKPLEPILDQFGLVLVSASEQKDPWQGRSTVAITLKIMAKAFSAEDDTVVNIIKFLVDDGGLVDREPIVRQEMKEAGVELITLHGSQNSKDLIPIFEEALSSSTDS----ALKENVIILYGTLARHLQQSDARIHTIIERLLSTLDTPSADIQQAVSACIAPLVFQFKQKVGDYLGILMEKLLNPTVASSMRKGAAWGIAGLVKGYGISALSEFDIIRNLIEAAEDKKEPKRRESVGFCFQYLSESLGKFFEPYVIEILPNILKNLGDAVPEVRDATARATKAIMAHTTGYGVKKLIPVAVSNLDEIAWRTKRGSVQLLGNMAYLDPTQLSASLSTIVPEIVGVLNDSHKEVRKAADESLKRFGEVIRNPEIQKLVPVLLQAIGDPTKYTEEALDSLIQTQFVHYIDGPSLALIIHIIHRGMHDRSANIKRKACKIVGNMAILVDTKDLIPYLQQLIDEVEIAMVDPVPNTRATAARALGALVERLGEEQFPDLIPRLLDTLSDESKSGDRLGSAQALAEVISGLGLTKLDEMLPTILAGVT--NFRAYIREGFMPLLLFLPVCFGSQFAPYINQIIQPILSGLADNDENIRDTALKAGKLIVKNYATKAVDLLLPELERGMFDENDRIRLSSVQLTGELLFQVTGIS---SRNEFSEEDGDHNGEFSGKLVDVLGQDRRDRILAALFVCRNDTSGIVRATTVDIWKALVPNTPRAVKEILPTLTGMIVTHLASSSNVLRNIAAQTLGDLVRRVGGNALSQLLPSLEESLIETSNSDSRQGVCIALYELIESASTETISQFQSTIVNIIRTALIDESATVREAAALSFDVFQDVVGKTAVDEVLPYLLHMLESSD--NSDFALLGLQEIMSKKSDVIFPILIPTLLAPPIDAFRASALGSLAEVAGSALYKRLSIIINALVDAIIGTSEDESTKGALELALDRVFLSVNDDEGLHPLLQQIMSLLKSDNIEKRIAVLERLPNFFDKTVLDFDVYIPNFVSHAILSLDDEDQRVVNGNFNALSTLLKKVDKPTLEKLVKPAKQSLALTGRQ--GQDVAAFKLP-RGPNCVLPIFLHGLMYGSNDEREESALAIADVVSKTPAANLKPFVSVITGPLIRVVGERFSSDIKAAILFALNVLFIKIPMFLRPFIPQLQRTFVKSLSDATNETLRLRAAKALGALIEHQPRVDPLVIELVTGAKQATDEGVKTAMLKALLEVIMKAGSKLNENSKTNIVNLVEEEMLGSNDKLAVAYAKLIGSLSEILSNDEAHKILQDKVLNADL--DGETGKFAILTLNSFLKDAPTHIFNTGLIDEFVSYILNAIRSPDVYFGENGTIAAGKLLLLEGEKRSPFVKKDAAEPFKIGDENINLLINELSKAVLQPASNSTDVRRLALVVIRTLARFKFDECIKQYFDVVGPSVFSCLRDPVIPIKLAAEKAYLALFKLVEEDDMHTFNEWFAKISDRGNSIETVTGTTIQLRSVGDYTKRVGKRLANVERERIAAGGDAETMFSDRFEDEREIWAVGGVELTTDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : . *.:* ::.::. : . : . : :. :: *: *.* *: : : :: . : : .. .: : * * : . : *: . ::. . . . : . : : ..* : ..: :..:.. :: . : * *: : . : . : :.:: .*.. *. : .. .. : .. . : * . .::: .* . . : :.: . : : :* . : :. : : ::.. : . :. : : . : :: : :. : *. : . : * *. . : * : *. .: : . : . :: : . . : .: . :::.. : : : * . . . .: .: : .: : *:*:: : : * : : .:*. .: : . *: . . .: .. . :. : : :: ::: : *:: . . :. . * .** .:: : * :::.* .*. : :.:::* :: *: :* :: :: : .* : *:. : : : :* ..* : . : .. : : :. .*::: . :.:.: : : : :. :.: ::: : :* .* : : : ::: . . .:: . :: : : . .. : :. *.. : .: : . * : . * : :: . : . ..:: :.* : . *::* :* : : :: . :: :: .::: .: : : *:.:*: * *:** :. : ... :: *: * :*:::. :: :. .: : :::*:* .* **. *:: * :.: : **.: :.*:*:**: *..:... ::: *::* *:**:**::.* ::..*: :*:::*.*** ::*::*: *:. *: .*:.. . : *:..* : : . *:***:*:**:*** ** :*.: ::: * :***: : **.. *.*: *. **::****::.:**::* :** **:*: :*.:* : :.:*** ::* : *:* :**** .**:*** **: *.***:.*..***:: ** *** :*:::. ::*: :*.**:**** :.****:*: **:. *. .*::*:.*:*:*:**.******: :::*.: ***:: :: *.:*:*** *.* *** *** .: :: :::****:.*:.:*:****:*: :**. * :*:* *::**: *..* ** *:**.*:**:.***: *:.:::* *:: . :: .::::*:: :: ::* * .:*:**:. ** **..***:.* :*****:**: ::. ** .*: ****:**:*:**: *** ***** *:**::::*:: : : **:*. . . :: ** :**:*:*:.*:: *.*.. :** :::.:** :*.****:::****** *::: ***:. * :**:*******::* . *.:::* **:.* . :.*.******.* *:: *:* : : * .::* *.** * ****** :*: ::..:* *::::**::*: *.. : :: :* **:::*: ** *::* *:* * :**::: .*. * .***.** : * *: ::: *: . : *:*** *: * : ::: :: .* :: * :. * : :: :: :: .:: : : :.. :: .::**.:: * :: :. :: : . : * .:..* ** :* . :**:: ..:: * :::*::* .:. *: * * *:* * *******::*:**. :***:* :*.:*: *: : *: *:**** ** *:* * *. :*::*..**. *: : :.:**. *: .* : * .:: :**:** :: :* *:. :.:: : : :* : . :* : ::. . :::: :* * . : :.* :: .* .: ... . :* : : :. .. . *: . : :: :. * ::. .:: : .: .: * . * : : : : : ::: . :*: : : . :.:.. : . ", "identical_positions": 476, "similar_positions": 902, "identity": "17.25%" }, { "cls_id": "homologset.agr.MGI:2444256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q0PGW2-1", "uniprot_id": "DEN11_RAT", "id": "Q0PGW2-1", "name": "DENN domain-containing protein 11", "aln": "MVEQGDAAPLLRWAEG-PAVSVPQDPALQAGGWVRGGSG----GGRVAAEAPRRREPEEPAPPEVLLQ-------PGRLELGDVEE----------------------DQVVAVFVVTFDPRSGNMVEWCLPQD---IDLEGVEFKSMASGSHKVQSDFIYFRKG------------------PFFGLACFANMPVESELERG-ARMKSVGILSPSYTLLYRYMHFLENQVRHQLEMPGHYSHLAAFY-----EDKKGVLHAG-PGRGGSLPPVYWLPSIHRYMYPEMKITHPAGCMSQFIKFFGEQILILWKFALLRKRILIFSPPPVGVVCYRVYCCCCLANVSLPG--IGGTIPES--KPFFYVNVADIESLEVEVS---YVACTTEKIFEEKRELYDVYVDNQNVKTHHDHLQPLLKLNSADRE--KYRRLNEQRQMLLYSQEVEGDYSPCE----------------------------------------------------------EDLFVLFFLEQNNRIFQTLLEVSASQD-------KTLTAEHARGMGLD--PQGDRSFLMDLLEAYGIDVMLVIDNPCCP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHG7-1", "uniprot_id": "DEN11_MOUSE", "id": "Q3UHG7-1", "name": "DENN domain-containing protein 11", "aln": "MVEQGDAAPLLRWAEG-PAVSVPQDPALQAGGWVRGGSG----EGRVAAEAPRRREPDEPAPPEVLLQ-------PGRLELGDVEE----------------------DQVVAVFVVTFDPRSGNMVEWCLPQD---IDLEGVEFKSMASGSHKVQSDFIYFRKG------------------PFFGLACFANMPVESELERG-ARMKSVGILSPSYTLLYRYMHFLENQVRHQLEMPGHYSHLAAFY-----EDKKGVLHAG-PGRGGSLPPVYWLPSIHRYMYPEMKITHPAGCMSQFIKFFGEQILILWKFALLRKRILIFSPPPVGVVCYRVYCCCCLANVSLPG--IGGTIPES--KPFFYVNVADIESLEVEVS---YVACTTEKIFEEKRELYDVYVDNQNVKTHHDHLQPLLKINSADRE--KYRRLNEQRQMLLYSQEVEGDYSPCE----------------------------------------------------------EDLFVLFFLEQNNRIFQTLLEVSASQD-------KTLTAEHARGMGLD--PQGDRSFLMDLLEAYGIDVMLVIDNPCCP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4D1U4-1", "uniprot_id": "DEN11_HUMAN", "id": "A4D1U4-1", "name": "DENN domain-containing protein 11", "aln": "MVEQGDAAPLLRWAEG-PAVSLPQAPQPQAGGWGRGGGG----GARPAAEPPRRREPEEPAAPEVLLQ-------PGRLELGDVEE----------------------DQVVAVFVVTFDPRSGNMVEWCLPQD---IDLEGVEFKSMASGSHKIQSDFIYFRKG------------------PFFGLACFANMPVESELERG-ARMKSVGILSPSYTLLYRYMHFLENQVRHQLEMPGHYSHLAAFY-----EDKKGVLHAG-PGRGSSLPPVYWLPSIHRYMYPEMKITHPAGCMSQFIKFFGEQILILWKFALLRKRILIFSPPPVGVVCYRVYCCCCLANVSLPG--IGGTIPES--KPFFYVNVADIESLEVEVS---YVACTTEKIFEEKRELYDVYVDNQNVKTHHDHLQPLLKINSADRE--KYRRLNEQRQMLLYSQEVEEDYNPCE----------------------------------------------------------EDLFVLFFLEQNNRIFQTLLEVSASQD-------KTLTAEHARGMGLD--PQGDRSFLLDLLEAYGIDVMLVIDNPCCP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LX49-1", "uniprot_id": "DEN11_DANRE", "id": "Q1LX49-1", "name": "DENN domain-containing protein 11", "aln": "MVEQSDRAPLLDWEEIPPAELAPSVPSPDTGDSLQSGLSSYPTEATLGADITLNTSPTRPSSVAAVHSPHKQHSGPGGDALAEEDEPGDCAFHGLSVRDRRITGWEEKDQIVAVFVVTFDTRSGNMIEWCLPHD---VNLEGVEFKSMASGSHRISSDFIYFRKG------------------CYFGLACFANMPVESELERG-ARMKSVGILSPSYTLLYRYMHFLENQVRHQLQCPGQYSPLEAFY-----EDKKAVLPSGGNGLVTACPTSALAPIVNRCMHPEMKITHPAGCMSQFIRFFGEQIMVLWKFALLRKRILIFSPPPVGVVCYRVYCCCCLANVSIPG--MGVSVPEF--RPFFYINVADIPALETELS---YVACTTEKIFEEKKELYDVYIDNQNVKTHRESLQPLLRLNSADRE--KYRKLCEQRQLLLYSQEVDGDCTSNE----------------------------------------------------------EDLFILFFMEQNNRIFQTLSEVAVSAD-------PTLTAEHVRAMGLD--PQGDRGFLVDLLEIYGIDVMLVIDNPCCP----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36090-1", "uniprot_id": "ANR2_YEAST", "id": "P36090-1", "name": "Uncharacterized protein ANR2", "aln": "----------------------------------------------------MNSGGEEPTIKPNVFN-------ITQLLNSNGEK----------------------PGIACIFLSKFDMKKGNIIIWSKSINGAAIDLSNIEFKSLPAGIHEQTDDVVNFVVPKELDVCQTAKTTTYDYGIAYFKQNSFDIIENDNRIDRSKVQMFSLGVIIDVQNASSDSKKHFYKEIYHAYAANRYSSYLESLLGQWIRQRDLDKFDIFEKFFDENNQGHMAENSVEVFEHSPKERRHLVEYLPYWTRKLGPLIFPLWKASLLQSRILILVPQGESFELCNSLAYCVFLISMLPKNLIGNHVSDEYIKPIFTVSTSDIPFLESFKKGNGYVATTSEEILLYKPEIYDIVVKLTSSSTIEESPEKEVEILTASGEQNKATPLDLEVYEKLILGELQEDASTNATCRHHEVTEPISWLQFLIDGFFLLTTAGYLVAPYHLANNFKIPRHVSGPEPNNSEIQIAENLVRYFHRRTSNLYNDLKDVIQKSENIDSEQPITIAASFLTKLNLDCFSKQDHQFVKDIALKWFQRSIDISNLPECLGNLC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .*: : . .: :: :..:*: .** :.**:: *. . : ::*..:****:.:* *. .*.: * :* .* : :..::*. .:* *:*:: . :.: ::: * * * :: : . : :. :. : * . :. : : :* *: *** :**:.****: * .. . . * : :* :* :.: :*:* :..:** ** . *** *:*:*: * *:**: :. . .* .: : :.: :*. * * * : * *:: * .. : :: :* .:...::: * :* . : *::*.. :.** .: *: *: *: : : : : * * ", "identical_positions": 77, "similar_positions": 145, "identity": "12.9%" }, { "cls_id": "homologset.agr.MGI:2444259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZL10-1", "uniprot_id": "D3ZL10_RAT", "id": "D3ZL10-1", "name": "", "aln": "-----MLLILFLMMICLHVCANQDSGPE----YADVVFLVDSSDHLGMKSFPLVKTFIQKLVSSLPVEANKYRVALAQYSDALHNEFHLGAFKNRNPMLNHLKKNFGFIGGSLKIGNALQEAHRTYFSAPTNGRDKKQFPPILVVLASAESEDDVEEASKALREDGVKIISVGVQKASEEDLKAMATS-------------------------------------------------------------------------------------------------------------------------------------------------QFHFNLRTARDLS-----------------------------------MFAPNMTQIIKDVTQYREAMTDDIIVEACQGPSVADVVFLLDMAINGSQENLDHLKAFLGESVSALDIKENCMRVGLVAYSNETRVISSLSMGVNKTEVLQRIQDLSPHVGQAYTGAALRKTRKEVFSAQRGSRKNQGVPQIAVLVTHRASDDNVTKAAVNLRREGVTVFTMGVEGANPEQLEKIASYPAEQFTSKLSNFSELATHNQTFLKKLRNQITHTVSVFSERTETLKSACVDTEEADIYLLIDGSGNTQPTDFHEMKIFLSEVVDMFNIAPHKVRVGAVQYADTWDLEFEISKYTNKPDLGKAIDNIRQMGGNTNTGAALNFTLTLLQRAKKQRGNKVPCHLVVLTNGMSQDSVLGPAHKLREENIRVHAIGVKEANQTQLREIAGDEKRVYYVHEFDALRDIRNQVVQEICAEEACRDMKADIMFLVDSSGSIGLENFSKMKVFMKNLVSKSQIGADRVQIGVVQFSHENREEFQLNTFMSQNDIANAIDQMAHIGETTLTGSALTFVSQYFSPEKGARPNVRKFLILITDGEAQDIVKDPAVALRKDGVIIYSVGVFGSNVTQLEEISGKPEMVFYVENFDILQHIEDDLVLGICSPREE-CKRIEVLDVVFVIDSSGSIDYQEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDELGTKLEVISVLQNDQPMGGNTYTAEALAFSDHMFTEARGSRLHKGVPQVLIVITDGESHDAEKLNATAKALRDKGILVLAVGIAGANTWELLAMAGSSDKYYFVETFGGLKGIFSDVSASVCNSSKVDCEIEKVDLVFLMDGSNSIHPDDFQKMKEFLASVVQDFDVSLNRVRIGVAQFSDSYRSEFLLGTFTGEKEISTQIEAIQQIFGYTHIGDALRKVKHYFRPDTGSRINAGTPQVLLVLTDGRSQDEVAQAAEELRHKGVDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVKKRIVRNICTSG--GESNCFVDVVVGFDIS-SQRRGQTLLEGQPWMGTYLQDLLRAISSLNGVSCEVGTETQVSIAFQVTNAMERYPS--KFEIYSENILSSLQGVTVNGPSRLNPNLLSSLWDTFQNKSAARGKVVLLFSDGLDDGVEKLEQKSDELRKEGLNALITIAVDGAADSSDLADLLYIEFGKGFEYRTQFTIGMGNLGSHLSKQLINVAERTCCCLLCKCTGWDGAMGDPGSAGEKGPPGFKGSEGYLGEEGIAGERGALGPMGEQGTKGCLGAKGPKGARGLSGEEGEVGEDGLDGLNGEQGDSGIPGRRGERGDAGSQGSPGKRGASGDRGPKGLRGDPGTPGRDNSIQGPKGLKGDPGRQGRRGWPGSPGTPGSRRKMVVHGRRGHTGPQGNPGITGPDGLEGSPGLKGPQGPRGEVGEKGEKGGFGMKGPQGPPGPKGRAGNQGHWGSQGSKGEPGDLGEKGAAGFPGPRGLQGDDGSPGYGSIGRKGTKGQEGFPGESGPKGDIGDPGDPGEAGPKGARGKTVSAGIPGEPGSPGEPGPPGRKGMKGARGLASFSTCDLIQYVREHSPVRHG------KPECPVHPTELVFVLDQSRDVTEQDFERMKGMMASLVRDIKVRDASCPVGARVAILAYNSHTRHLIRFSDAYRKDQLLREIKALPYEKSSDSREIGKAMRFISRNVFKRTLPGAHVRRIATFFSSGQSADVQSITTAAMEFSALDIIPVVIAFSNVPSVKRAFSIDDTGTFQVLVVPSRPDQVPALERLQRCTFCYDLCKPDASCDQAKPP-IQSYLDAAFLL--DSSWHVGGAEFEDMRDLLEALLDHFEIASEPETSVTGDRVALLSHAPVDFLPNTQRSPVRTEFNLTTYSSKHLMKRHVEQAVQQLNGDAFLGHALRWALDNVFLNTPNLRRNKVIFVISAGETSHLDAETLKKESLRAKCHGYALFVFSLGPDWDDKELEDLASHPLDQHLIQLGRIHKPDHGYGVKFVKSFINSIRHGINKYPPVNFKAKCS--------RLSSAAPKLSPRQFRSFVPGPQKALLKDHTLEAAKLFQDKKRLSS-----ILRSGR-AALSSHSRSTR---------------------------------YSFKQGREATKATSKLGKRSD-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C6K9-1", "uniprot_id": "CO6A6_MOUSE", "id": "Q8C6K9-1", "name": "Collagen alpha-6(VI) chain", "aln": "-----MLLVLCLTMICFHVCVNQDSGPE----YADVVFLVDSSDHLGLKSFPLVKTFIHKMISSLPIEANKYRVALAQYSDALHNEFQLGTFKNRNPMLNHLKKNFGFIGGSLKIGNALQEAHRTYFSAPTNGRDKKQFPPILVVLASAESEDDVEEAAKALREDGVKIISVGVQKASEENLKAMATS-------------------------------------------------------------------------------------------------------------------------------------------------QFHFNLRTARDLS-----------------------------------VFAPNMTEIIKDVTQYREGMADDIIVEACQGPSVADVVFLLDMAINGSQEDLDHLKAFLGESISALDIKENCMRVGLVTYSNETRVISSLSTGNNKTEVLQRIQDLSPQVGQAYTGAALRKTRKEIFSAQRGSRKNQGVPQIAVLVTHRASEDNVTKAAVNLRREGVTIFTMGIEGANPDELEKIASHPAEQFTSKLGNFSELATHNQTFLKKLRNQITHTVSVFSERTETLKSACVDTEEADIYLLIDGSGSTQPTDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADTWDLEFEISKYSNKPDLGKAIENIRQMGGNTNTGAALNFTLKLLQRAKKERGSKVPCHLVVLTNGMSRDSVLGPAHKLREENIRVHAIGVKEANQTQLREIAGEEKRVYYVHEFDALRNIRNQVVQEICAEEACRDMKADIMFLVDSSGSIGPENFSKMKMFMKNLVSKSQIGADRVQIGVVQFSHENKEEFQLNTFMSQSDIANAIDRMTHIGETTLTGSALTFVSQYFSPDKGARPNVRKFLILITDGEAQDIVRDPAIALRKEGVIIYSVGVFGSNVTQLEEISGKPEMVFYVENFDILQHIEDDLVLGICSPREE-CKRIEVLDVVFVIDSSGSIDYQEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDELGTKLEVVSVLQNDHPMGGNTYTAEALAFSDHMFTEARGSRLHKGVPQVLIVITDGESHDAEKLNTTAKALRDKGILVLAVGIAGANSWELLAMAGSSDKYYFVETFGGLKGIFSDVSASVCNSSKVDCEIEKVDLVFLMDGSNSIHPDDFQKMKGFLVSVVQDFDVSLNRVRIGVAQFSDSYRSEFLLGTFTGEREISTQIEGIQQIFGYTHIGDALRKVKYYFQPDMGSRINAGTPQVLLVLTDGRSQDEVAQAAEELRHKGVDIYSVGIGDVDDQELVQITGTAEKKLTVHNFDELKKVKKRIVRNICTSG--GESNCFVDVVVGFDIS-SLQRGQTLLEGQPWMGSYLQDLLRAISSLNGVSCEVGTETQVSIAFQVTNAMERYPS--KFEIYSENILSSLQGVTVNGPSRLNANLLSSLWDTFQNKSAARGKVVLLFSDGLDDGIEKLEQKSDELRKEGLNALITIAVDGAADSSDLADLLYIEFGKGFEYRTQFTIGMRNLGSQLSRQLINVAERTCCCLLCKCTGGDGAMGDPGSAGKKGPPGFKGSDGYLGEEGIAGERGASGPMGEQGTKGCFGAKGPKGTRGLSGEEGEVGEDGLDGLDGEQGDHGIPGRRGEKGDEGSQGNPGRRGAAGDRGAKGLRGDPGTPGRDSSIQGPKGLKGDLGRQGRRGWPGSPGTPGSRRKMVVHGRRGHIGPQGNPGTPGPDGLAGSPGLRGPQGPRGEVGEKGEKGSLGMKGPQGPPGPGGQAGSQGHLGSQGNKGEPGDLGEKGAAGFPGPRGLQGDDGSPGYGSIGRKGTKGQEGFPGESGLKGDIGDPGDPGEAGPKGARGKTVSAGIPGEPGSPGEPGPPGRKGVKGARGLASFSTCDLIQYVRDHSPGRHG------KPECPVHPTELVFVLDQSRDVTEQDFERMKGMMVSLVRDVKVREANCPVGARVAILAYNSHTRHLIRFSDAYRKDQLLTAIKALPYERSSDSREIGKAMRFISRNVFKRTLPGAHVRRIATFFSSGPSADAQTITTAAMEFSALDIVPVVIAFSNVPSVKRAFSIDDTGTFQVIVVPSGSDEGPALERLQRCTFCYDLCKPDASCDQAKPPPIQSYLDTAFLL--DGSRHVGSAEFEDMRDFLEALLDHFEITSEPETSVTGDRVALLSHAPLDFLPNTQRSPVRTEFNLTSYSSKRLMKRHVDQAVQQLHGDAFLGHALGWALDNVFLNTPNLRRNKVIFVISAGETSHLDAETLKKESLRAKCHGYALFVFSLGPDWDDKELEDLASHPVDQHLIQLGRIHKPDHGYSVKFVKSFINSIRHGINKYPPVNLKAKCN--------RLGSRDLKPPPRQFRSFVPGPQKANLKDHTAEAAKLFQDKKRLSS-----MLKGGR-ATISSLSRSTR---------------------------------YAFKQGKEAIKATSKLGKRSA-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NMZ7-1", "uniprot_id": "CO6A6_HUMAN", "id": "A6NMZ7-1", "name": "Collagen alpha-6(VI) chain", "aln": "----MMLLILFLVIICSHISVNQDSGPE----YADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMATS-------------------------------------------------------------------------------------------------------------------------------------------------QFHFNLRTVRDLS-----------------------------------MFSQNMTHIIKDVIKYKEGAVDDIFVEACQGPSMADVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSVFSERTETLKSGCVDTEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGEEKRVYYVHDFDALKDIRNQVVQEICTEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQYFSPTKGARPNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMVFYVENFDILQRIEDDLVFGICSPREE-CKRIEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFSDHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGSSDKYFFVETFGGLKGIFSDVTASVCNSSKVDCEIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNTHIGAALREVEHYFRPDMGSRINTGTPQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQITGTAEKKLTVHNFDELKKVNKRIVRNICTTA--GESNCFVDVVVGFDVS-TQEKGQTLLEGQPWMETYLQDILRAISSLNGVSCEVGTETQVSVAFQVTNAMEKYSP--KFEIYSENILNSLKDITVKGPSLLNANLLDSLWDTFQNKSAARGKVVLLFSDGLDDDVEKLEQKSDELRKEGLNALITVALDGPADSSDLADLPYIEFGKGFEYRTQLSIGMRELGSRLSKQLVNVAERTCCCLFCKCIGGDGTMGDPGPPGKRGPPGFKGSEGYLGEEGIAGERGAPGPVGEQGTKGCYGTKGPKGNRGLNGQEGEVGENGIDGLNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKGEPGDLGEKGAVGFPGPRGLQGNDGSPGYGSVGRKGAKGQEGFPGESGPKGEIGDPGGPGETGLKGARGKMISAGLPGEMGSPGEPGPPGRKGVKGAKGLASFSTCELIQYVRDRSPGRHG------KPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSHARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPGAHTRKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDDTGTFQVIVVPSGADYIPALERLQRCTFCYDVCKPDASCDQARPPPVQSYMDAAFLL--DASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLSTPNLRRNKVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHPLDHHLVQLGRIHKPDHSYGVKFVKSFINSIRRAINKYPPINLKIKCN--------RLNSIDPKQPPRPFRSFVPGPLKATLKEDVLQKAKFFQDKKYLSR-----VARSGRDDAIQNFMRSTS---------------------------------HTFKNGRMIESAPKQHD---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TBZ3-1", "uniprot_id": "A0AB32TBZ3_DANRE", "id": "A0AB32TBZ3-1", "name": "", "aln": "MGKAQTFLFVFLFASCFLVSTAQLTGCQDENPPYDIVFLVDSSSSIGTRDFREVKTFMHTFVDGLEIDTKKVQVGVVQFSTDPHKEFLLGEYANKAELFRKIDN-LPYRTGGTYMGKAMNFLKDNYFTSAGGSRVSEKVPQVVVVITDGDSTDDIKGPAEDLRKKGIIIFAIGVGSTNMTELKAIASTPPERFVVNIDNYQALQGLTTTMKETVCVLMRDQGKALAPKFTDVFVLVDSTAQGETQQIRELLNRLLVQLNVGDGSNKIALAQFGENVVKEFLFKDYQTAQKAREFINRFEPRLNGERKLGKAIDYVRTNFLNTVSGSRIAKGYKQYLLVLRTGDSYDSTVRAIRTMKNEDVSVIDIRLEPNLQSLFPSLRAFQIDQNVIDVAADVTKRIQEKEVFNVTGDCRSAQVADIVFIVDESGSITRNNFELIKRFLHRIISGLEVNSDSVRVGMVLYNDRPSAEFYLDTFANKNDIMNYIKIIPYRGGGTATGAALKFAQNNLFTQKRGSRKALGVKQIAIVMTDGESEDDVTTTAAELRRSGVTVYALGVKNASVEELKKIGSYPEHEFVFNVGSFLMLSSLEKSLRKSLCKVVVNRRFDKNNR-LLLKQGCVNTEEADIYFLLDNSGSTR-ADFEDVKKFILGSLQLFNIGPNRVRVGVVKVDRNPTLQFSLTEHKNRASFEAAVRGISQPVGGSEKGKALKYVASLFNQAKASRPAKVQEILIVITDKTSQDDVGDPAEELRIQGVSVYAIGVKDASQDELLKMTADETKDFYVTNYDALNVLKREIVTDICSQEACKNKVADIMFLIDGSSSIYGPDFTSMKTFITKVVNGTIIGEDSVHVGVVQFSNNPQEQFPLNRYFDQNELEEAIDGIEQLTGDTYTGKALSFISKYFDASNGGRPDVPQFLVVITDGEAHDAVAVPAKAIRDKGVTIFSIGVASVNTTQLWEISGTQDKVYVQRDFDALHSIDKNLQFKLCSSHPGGCPSTQLADVIFLVQCTRQIRLQDFEKIKSFLISVVNSTQIGDNLIRFGVIVYSDTP-SQFSLNQYNTRRQIAEAITSLKSPAVSGYTARALAYSLTYFTEANGGRQKRGVPQMLFMITDGDARDRENLRARADEFAAKQINVYGIGVARAQDSELEIITKSKNKIFHVNNYDNLQDLQMNVSGVLCNATKPVCQNEVADLVFLIDGSESISEESWITVIAFLLNVVDKLRIGPELFRVGIAQFSSVYQKEFYMNEYKDADGVKSAIRRITQIKEGTLIGKALSNVVEFFQEDKGSRKQSGVPQNLVLITDGVSSDRVNEAADQLRNLGINVFAIGIGAVSLQQLSYIAGSPDRLFKVQNFNYLNLTTATFVDALCVPLPLAQASCTIDIGIGFDNSRTSSSSRSIFRDQMKLQTYLPEIIRSISEVHNLCCITKPTIKTNIGFRLVDATGKRLDDFSFEEYDVGVLNKVMALQTSQSLKFNNLLLRSFEEKFR-ASNSFVKVLIIFTDGLDEPVENLLSTVNSLRTNGVKALLTVALDGYKSTT---DLQRLEFGRGLRYKQLLSIGMQSVASVMQKEIDNIASRECCNVACKCSGHEGSRGFQGLPGSKGLPGRRGNSGYPGEEGGHGERGLPGLNGTRGNQGCPGRRGLKGGRGYRGENGEEGDNGLDGVDGEQGKTGAPGSPGERGDPGNPGPTGISGSSGSPGQRGLRGDPGNSGLDNNARGRKGDAGSAGMQGDPGPDGLAGQSGENGRPGQSGRRGTAGLPGPRGPPGDPGLQGLPGGSGPQGPFGPPGPVGQRGFVGLPGPQGSPGSPGRPGTKGSLGSRGQKGQPGDPGEKGSLGSAGSRGLPGKDGNDGYGYPGLKGQKGDSGFPGYPGLQGELGFKGTNGGVGPKGSRGRGGNAGRTGPPGDPGSGGMTGHRGPKGPRGARQMSDCQLISYVRDNCMCCKGRCVLLDNIKCPAYPTDLVIGMDMSEDVTPQGFERMRSVVLRLLDNMKIAESSCPTGARVALVSYSSFTKYLIRFNDYHRKKQLIDAVNNIALERTSNRRNIGAAMRFVGRNVLKRVRKGILMRKVAIFLTAGESQDSISLTTAILEYKALNIKLGVIALRNVPAIRRAFEADESQSFILTVLGRVQDQNATLSKIQSCVICYDPCRPARECEGTNLPSAPQELDMDFVMVVDGSRSILADEFKGVKEVLGGVLDQIVVSSQPTRADRQARVALYQQTSTYSDP----QPAHEIFSLREFSDRNLMKTSIIQKLKQTGGSHELGSTLEFAFKKCFNAVPESRKNKMLLAIIGEETALQEKKRLDSFSRLAKCSGIVLFTLTVGDSIASSQVEELASYPLEQHIIHLGHLKHGEQEYTQRFMRTFFHILSKNMNTYPHPSLQSQCRNFQESPGQRLDFEAAERPVYRVPVLSTVYPDVQVEEDMEEEDTAPETEDQQSSGRGDSIIQSPADNTDSLCRQSSDRGTVCGDYMQRWYYNPAVRGCLPFWYGGCGGNGNRFSSERECLQTCGKKNPEVIPQTQVETALFNDACLMKQDVGPCSNYVLSWYYDIQQNECSQFWFGGCEGNKNRFETRAECEALCLKDIQPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 767, "similar_positions": 863, "identity": "29.66%" }, { "cls_id": "homologset.agr.MGI:2444263", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BTG3-1", "uniprot_id": "T11L1_MOUSE", "id": "Q8BTG3-1", "name": "T-complex protein 11-like protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSENLD-KSHVDEAGEAEAAASEQGLEGALECSDETLQKKVKSDSPSSQRVGRPHSSPARLVTVEELLETAKGVTNMALAHEIVVTGDFRINA-VELAEGSLEKRVKEIVHKAFWDCLSVQLSEEPPTYDHAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLELIKQEAENGALDISKLAEFIIGMMGILCAPARDEEVKKLK----------GIKEIVPLFRAIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERRKFQEVLERQPNSLDFATQWLEEATNDLLSQKYKHALPAGGGAAGSGDAPLLTPVSVQNFAYLKLLKWDHFQRPFPETVLMDQSRFQELQLQLEQLAVLGAVLLVTFSTAAPGISGHAD---------FAEKLKMMVKTLLTDMHLPSFHLEDALASIGEKVCLEVSSCLSLCG-----------SSPFSVAKETVLKGQIQALASPEDPIRRIMESRIFTFLETYLASGHQKPLP-----------------------------------------------TVPGG---------LGPIQKELEEVAVKFVRLVNYNKMVFCPYYDAILSKLLLRS----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K6F1-1", "uniprot_id": "A0A0G2K6F1_RAT", "id": "A0A0G2K6F1-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSENLD-KSHVNEAGESKSAASEEGQKGALECSDEALQEKVKSDSPSPLRVGRPHSSPPRLVTVEELLETAKGVTNMALAHEIVVNGDFRINA-VELAEGSLEKRVKEIVHKAFWDCLSVQLSEDPPTYDHAIKLVGEIKETLLSFLLPGHTRLRNQITETLDLELIKQEAENGALDISKLAEFIVGMMGILCAPARDEEVKKLK----------DVKEIVPLFRAIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEVLEKQPNSLDFVTQWLEEASNDLLTQKCKHALPAGGGAAGSGDAPLLTAASVQNYAYLKLLKWDHFRRPFPETVLMDQPRFQELQLQLEQLALLGAVLLVTFSTSAPAVSGHAG---------FAEKLKTVVKILLADVHLPSFQLEDALTSIGEKVCLEVSSCLSMCG-----------SSPFSVSKETVLKGQIQALASPDDPIRRIMESRILTFLETYLASGHQKLLP-----------------------------------------------TVPGG---------LGPIQKELEEVAVKFVRLVNYNKMVFCPYYDEILSKLLLRS----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NUJ3-1", "uniprot_id": "T11L1_HUMAN", "id": "Q9NUJ3-1", "name": "T-complex protein 11-like protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSENLD-KSNVNEAGKSKSNDSEEGLEDAVEGADEALQKAIKSDSSSPQRVQRPHSSPPRFVTVEELLETARGVTNMALAHEIVVNGDFQIKP-VELPENSLKKRVKEIVHKAFWDCLSVQLSEDPPAYDHAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLDLIKQEAENGALDISKLAEFIIGMMGTLCAPARDEEVKKLK----------DIKEIVPLFREIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEILERQPNSLDFVTQWLEEASEDLMTQKYKHALPVGGMAAGSGDMPRLSPVAVQNYAYLKLLKWDHLQRPFPETVLMDQSRFHELQLQLEQLTILGAVLLVTFSMAAPGISSQAD---------FAEKLKMIVKILLTDMHLPSFHLKDVLTTIGEKVCLEVSSCLSLCG-----------SSPFTTDKETVLKGQIQAVASPDDPIRRIMESRILTFLETYLASGHQKPLP-----------------------------------------------TVPGG---------LSPVQRELEEVAIKFARLVNYNKMVFCPYYDAILSKILVRS----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W461-1", "uniprot_id": "Q9W461_DROME", "id": "Q9W461-1", "name": "T-complex protein 11-like protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAQEN-RSEQSGQSGDHEEHEERRIRTDSESSVESMTRFVLPSLDG---------TPPKIVTLDEVSSMFKNLRNMELAHEIALNPDFKLQK-YEPPSDSLEGAIKKMVHKAFWDLLRVQLDRQPPSYDQAIRLLAEIKECFPQLLSPNNERALAHINEVLDDSVIRQQAERGTLDFRAYANFVINILSRSCSPARDEAVAALR----------KIDDVVDTFRCILELMTLMKLDMANFMLRLARTEIAANSVQYEKEKFSKYLREFHGNVGFP------ATEDWLQRHR----------SGSSDD------ETIYNAYMQLIDYP-ADKEFPELLRIDKERFAGLSWRAQRLILC--ASLISVAQGMPIISQRRE---------NRIKLAQQLDIIVQDIKN-QDQVASTIESCYEQIRSFVNKALEQEN-----------LPALSDADQAALKNQVLKLANKTSPVPSLMAKRLDGYVRVTLRS--NGSIP-----------------------------------------------PPPSG---------FADYQEELVAFIASFRRLVSYNHAVFGEHFHQILNKTLPGEETEATTSTASGINPGQAQTAKP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40317-1", "uniprot_id": "SOK1_YEAST", "id": "P40317-1", "name": "Protein SOK1", "aln": "MDQPRTHSGPTTASNPAPSSTNSSSAPSATNSKQERSSSSLSKPSSVVPSKDSPDGDAIAKTQAAALKNDMKSGDTSTLDGSSQNIIPNRASMQKYIDQSSDLLSRSSGVITPSMSLNASTNATNNDSSGNSANSSDLKIPIDRDNTIFKTFDTKTGQFLKNDDNEEEIRRNNKVDSIPPKNIYTNINNPSPSPPPSSKQPPSASAPQLPPATEPHKEQAAQQQPPGNASNFLRIFSNKKMRSHSVPTILHSSLRKLSSHNQYYRNQNILLNHPTPSGISKKKFSRNHHQPYLHSNNPLSSNPLSLKRAIFLNQQISGNASTNANNDNINNSTATSMTNQSFLSSSNFDLTLEDRINYIKATPTPVPFPPINLQGLKEIDLQEILKNPQLRHDIIFDPLLQFRPNLDGERGNKKRQLANIYWNDVQNEIYVYSKRPEIFQYNRSRLVPLFDTLRDVLLTIVPQKESPMINNVLDTELNIQELLKGSLIMSNLSGWLADLFKHHCAPMRDPWVDKMSNKFKEAERDSSLTRLIEGLRLVFQILETMKLDIANHQIRILRPALLSNAVEFEKQYFNTLIASKRVNLNTSLLWFDKKFNENVTAGLVR---------NPSSITIPDVYNICIRSIINLLSCRKMVREYPTPLSFDHARLILLRADIRQIVCILVCRLLFQQLVANDPSMDKATKEYVIHTYSTKRLKNEIISIITDEHGNCRWTKNTMSIAVHLCKVIDDLHREYDNNGSCEQARRPQLPSLDNSKITFAKSWLSKQTQPLSEVYGVLENRVFKSLEDAIFNRSECTIDGRVKQDFVYLYNTNNGNVGSTNTLSTTTDTASVKISPSLMSPSKTSTTTPTGNAIASRGLFAATELEEFENVYRHLYALINLHWSVFGPHYIEMLGDKVNKKGI--------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . .: . . : . : : *. : : . . : * * *:* . :::. : .. : : :: : . : : * .. : :*: :. :* : *.:.** .: *: .*:* : : :: .:: *:* ** * : : :: :* ::.:: **:*:**. : *. : ::*::*:. *. : .:. :: : .... : ::*:. : :* : :*: *: * .:: *: * :* : :: * : ..: . . . . ..: . : *. : :. . : :: .*: :. : . : : . * * . .*: . : *:. : ** :: :*.. : . ", "identical_positions": 47, "similar_positions": 158, "identity": "5.05%" }, { "cls_id": "homologset.agr.MGI:2444266", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0W6-1", "uniprot_id": "A0A8I6A0W6_RAT", "id": "A0A8I6A0W6-1", "name": "(E3-independent) E2 ubiquitin-conjugating enzyme", "aln": "----MADPAAPAPAP-APAQAQAAAAPTPAAAP-AAAPPPAPATDSASGPSSDSGPEAGSQRLLFSHDLVSGRYRGSVHFGLVRLIHGEDSDSEGEEDGRGSSGCSEAGGAGHEEGRASPLRRGYVRVQWYPEGVKQHVKETKLKLEDRSVVPRDVVRHMRS----TDSQCGTVIDVNIDCAVKLIGTNCIIYPVNSKDLQHIWPFMYGDYIAYDCWLGKVYDLKNQIILKLSNGARCSMNTEDGAKLYDVCPHVSDSGLFFDDSYGFYPGQVLIGPAKIFSSVQWLS-GVKPVLSTKSKFRVVVEEVQVVELKVTWITKSFCPGG------TDSVSPPPSVIAQENLGRVKRLGCFDHAQRQLGERCLYVFPAKVEPAKIAWECPEKNCAQGEGSMAKKVKRLLKKQVVRIMSCTPDAQCSRDHAMEDPDKKGEARAGSEVGSASPEEQLDGSASPVEMQDEGSEELHETGEPLPPFLLKEGGDEGLHSAEQDADDEAADDTDDTSSVTSSASSTTSSQSGSGTGRKKSIPLSIKNLKRKHKRKKNKITRDFKPGDRVAVEVVTTMTSADVMWQDGSVECNIRSNDLFPVHHLDNNEFCPGDFVVDKRVQSCPDPAVYGVVQSGDHVGRTCMVKWFKLRPSGDD-VELIGEEEDVSVYDIADHPDFRFRTTDIVIRIGNTEDGALPKEDEPSVGQVARVDVSSKVEVVWADNSKTIILPQHLYNIESEIEESDYDSVEGSTSGASSDEWEDDSDS---------------------------------------------------------------------------------WETDNGLVDDEHPKIEDLAAILPTEQPAAPEEDKGVVISEEAATAAIQGAVAMAAPVAGLMEKAGKDGPPKSFRELKEAIKILES--------------------------------------LKNMTVEQLLTGSPTSPTVEPEKPTR---------------------------------EKKFLDDIKKLQENLKKTLDNVAIAEEEKMEAVPDTERKED-KPEVQSPVKAEWPSETPVLCQQCGGRPGVTFT-----------------SAKGEVFSVLEFAPSNHSFKKIEFQPPEAKKFFSTVRKEMALLATSLPDGIMVKTFEDRMDLFSALIKGPTRTPYEDGLYLFDIQLPNIYPAVPPHFCYLSQCSGRLNPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEPYYNEAGFDSDRGLQEGYENSRCYNEMALIRVVQSMTQLVRRPPEVFEQEIRQHFSVGGWRLVNRIESWLETHVVLERAQALPNGVPKDSSSLEPQAAAELSDSGREEPEDVGMTPGEASQGSDSEGGAQGPASASREHPEQT-ETAPDASAPPSVRPKRRRKSYRSFLPEKSGYPDIGFPLFPLSKGFIKSIRGVLTQFRAALLEAGMPESTEDK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZPJ3-1", "uniprot_id": "UBE2O_MOUSE", "id": "Q6ZPJ3-1", "name": "(E3-independent) E2 ubiquitin-conjugating enzyme UBE2O", "aln": "----MADPAAPAPA-----QAQAAAAPTPAAAPAAAAPPPAPATDSASGPSSDSGPEAGSQRLLFSHDLVSGRYRGSVHFGLVRLIHGEDSDSEGDDDGRGSSGCSEAGGAGHEEGRASPLRRGYVRVQWYPEGVKQHVKETKLKLEDRSVVPRDVVRHMRS----TDSQCGTVIDVNIDCAVKLIGTNCIIYPVNSKDLQHIWPFMYGDYIAYDCWLGKVYDLKNQIILKLSNGARCSMNTEDGAKLYDVCPHVSDSGLFFDDSYGFYPGQVLIGPAKIFSSVQWLS-GVKPVLSTKSKFRVVVEEVQVVELKVTWITKSFCPGG------TDSVSPPPSIITQENLGRVKRLGCFDHAQRQLGERCLYVFPAKVEPAKIAWECPEKNCAQGEGSMAKKVKRLLKKQVVRIMSCTPDTQCPRDHSMEDPDKKGEARAGSEIGSASPEEQPDGSASPVEMQDEGSEELQETCEPLPPFLLKEGGDDGLHSAEQDADDEAADDTDDTSSVTSSASSTTSSQSGSGTGRKKSIPLSIKNLKRKHKRKKNKVTRDFKPGDRVAVEVVTTMTSADVMWQDGSVECNIRSNDLFPVHHLDNNEFCPGDFVVDKRVQSCPDPAVYGVVQSGDHVGRTCMVKWFKLRPSGDD-VELIGEEEDVSVYDIADHPDFRFRTTDIVIRIGNTEDGALPKEDEPSVGQVARVDVSSKVEVVWADNSKTIILPQHLYNIESEIEESDYDSVEGSSSGASSDEWEDDSDS---------------------------------------------------------------------------------WETDNGLVDDEHPKIEELAAILPAEQPTAPEEDKGVVISEEAATAAIQGAVAMAAPVAGLMEKAGKDGPPKSFRELKEAIKILES--------------------------------------LKNMTVEQLLTGSPTSPTVEPEKPTR---------------------------------EKKFLDDIKKLQENLKKTLDNVAIAEEEKMEAVPDTERKEE-KPEVQSPVKAEWPSETPVLCQQCGGRPGVTFT-----------------SAKGEVFSVLEFAPSNHSFKKIEFQPPEAKKFFSTVRKEMALLATSLPDGIMVKTFEDRMDLFSALIKGPTRTPYEDGLYLFDIQLPNIYPAVPPHFCYLSQCSGRLNPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEPYYNEAGFDSDRGLQEGYENSRCYNEMALIRVVQSMTQLVRRPPEVFEQEIRQHFSVGGWRLVNRIESWLETHAMQERAQVMPNGALKDSSSLEPMAAAELSDSGREEPEDVGMAPGEASQGSDSEGGAQGPASASRDHTEQT-ETAPDASAPPSVRPKRRRKSYRSFLPEKSGYPDIGFPLFPLSKGFIKSIRGVLTQFRAALLEAGMPESTEDK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0C9-1", "uniprot_id": "UBE2O_HUMAN", "id": "Q9C0C9-1", "name": "(E3-independent) E2 ubiquitin-conjugating enzyme", "aln": "----MADPAAPTPAAPAPAQAPAPAPEAVPAPAAAPVPAPAPASDSASGPSSDSGPEAGSQRLLFSHDLVSGRYRGSVHFGLVRLIHGEDSDSEGEEEGRGSSGCSEAGGAGHEEGRASPLRRGYVRVQWYPEGVKQHVKETKLKLEDRSVVPRDVVRHMRS----TDSQCGTVIDVNIDCAVKLIGTNCIIYPVNSKDLQHIWPFMYGDYIAYDCWLGKVYDLKNQIILKLSNGARCSMNTEDGAKLYDVCPHVSDSGLFFDDSYGFYPGQVLIGPAKIFSSVQWLS-GVKPVLSTKSKFRVVVEEVQVVELKVTWITKSFCPGG------TDSVSPPPSVITQENLGRVKRLGCFDHAQRQLGERCLYVFPAKVEPAKIAWECPEKNCAQGEGSMAKKVKRLLKKQVVRIMSCSPDTQCSRDHSMEDPDKKGESKTKSEAESASPEETPDGSASPVEMQDEGAEEPHEAGEQLPPFLLKEGRDDRLHSAEQDADDEAADDTDDTSSVTSSASSTTSSQSGSGTSRKKSIPLSIKNLKRKHKRKKNKITRDFKPGDRVAVEVVTTMTSADVMWQDGSVECNIRSNDLFPVHHLDNNEFCPGDFVVDKRVQSCPDPAVYGVVQSGDHIGRTCMVKWFKLRPSGDD-VELIGEEEDVSVYDIADHPDFRFRTTDIVIRIGNTEDGAPHKEDEPSVGQVARVDVSSKVEVVWADNSKTIILPQHLYNIESEIEESDYDSVEGSTSGASSDEWEDDSDS---------------------------------------------------------------------------------WETDNGLVEDEHPKIEE-PPIPPLEQPVAPE-DKGVVISEEAATAAVQGAVAMAAPMAGLMEKAGKDGPPKSFRELKEAIKILES--------------------------------------LKNMTVEQLLTGSPTSPTVEPEKPTR---------------------------------EKKFLDDIKKLQENLKKTLDNVAIVEEEKMEAVPDVERKED-KPEGQSPVKAEWPSETPVLCQQCGGKPGVTFT-----------------SAKGEVFSVLEFAPSNHSFKKIEFQPPEAKKFFSTVRKEMALLATSLPEGIMVKTFEDRMDLFSALIKGPTRTPYEDGLYLFDIQLPNIYPAVPPHFCYLSQCSGRLNPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEPYYNEAGFDSDRGLQEGYENSRCYNEMALIRVVQSMTQLVRRPPEVFEQEIRQHFSTGGWRLVNRIESWLETHALLEKAQALPNGVPKASSSPEPPAVAELSDSGQQEPEDGGPAPGEASQGSDSEGGAQGLASASRDHTDQTSETAPDASVPPSVKPKKRRKSYRSFLPEKSGYPDIGFPLFPLSKGFIKSIRGVLTQFRAALLEAGMPECTEDK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9XZ32-1", "uniprot_id": "Q9XZ32_DROME", "id": "Q9XZ32-1", "name": "UBC core domain-containing protein", "aln": "MMSDVAGAAAPGGTPGQPQQEQEQSLAEAAPRTPTLANPPPSSQELGRTPNQESRHNANSHSRRSGGGQVPSKAQGNTESQFFLEDGVFRIDRRGRVHFGLVTATTETYSSSEEED-VDSLSRGEVRVAFYPGGKEMVMTEQSIGLADRTLMPGDVVRRRLPGENVLAGQAGYVRDVNVRADVMVMGSRMVIKNVPAERLRPISEWNQYVPLCMDTWIGTIIDINECAVLKSSNGARVEITSNDFHKFKDAVSECDRT---VFNPNVFFPGNIVIGRMPPPDRVKNLTPEITHPLTRKGRAVYTVESVETTSINVDWSCRAIGNATGSDDTDSDPLKEPRSLIKGEELHKVKRLSLYESYELQIHDRFYLKYSKCDLLVKYADWENEQAEKYIPIFHAQKKMQRKASKLNASASTSGNARSVPKFRRMPNKISGMRLPRPPSDQTHNACKSSKRSKEDVLTSEDEDEFEEFMQPL----------DQSMTAEKEVEVAEDALPPSAATTAAAGVEVQAPRITMRSAKRRQVKKKIRSVKKTIYSPFNKKETTPKDGDEIVVETLVVYSSVTVVWQDGTVESGVHSTQLYPIHHLDNHEFFPGDFVTKANDIST-GATDYGVIQCVDHDARIAKVMWFNIYTNIDNPIPLFKGLEELSVYDMKDHTDYQYRPGTVVIRVSNFTG----EDVNSTAGQVIDNYPNGRVRVWWAKGHITLCYPQDLFQPFEQDEQNEQD-QDVYGSDGSEDSWETESENSHISSSDNDDDILTGIDRATEAMKVLEKMFRVLHPNRKAEVLYDLLDVYKNCRALDRLLNTKFFDEFNFKGIVRCKPITSKVCSDSATHERATPETPETSAAVPKESSTLQAELEPVLMDPSVQSSSSPTKRKSSTEMDEVLCKKSTDEISEEQDYQVEVVEVIEDPPLVREYRCKYNEMFANARRSIAKAIENRTKNDSGVHSRGEITSDESNNHPDSENKLDIKHPTINVMDDLEIELVASGDADVCEVFCYLIKFQMARIRKTVAVTLGKTNDNPKQEKEDVSDAEEAIEAVSQEAELANDGATECNTMAEDEAMEEPLNLNALSESLPAIDQTGPMACSSPSWSIIPDTPSVDENCFQVLPNAPAAHNFISNLITPANKAQYQRAVQREYLMLKSSLPNGVVVRAYEDRMDLMSVMMVGPKRTPYQNALFFFDFQFGRDYPKSPPVCHYISYCTDRLNPNLYEGGRVCVSLLGTWMGRDNEVWSPSSTMLQVLVSIQGLILVDEPYYNEAGYEKQRGTQLGNENSRVYNEMAIIKIAQSTVKQLTNPPLIFRNELIEHFKEFGTELYARMRAWSEYSLEAQRQNITK----IKDMPVEYKASCELPEFPLLP---CSRGFCIAVKRVLSQLQSELTALGANLVTDERNGIATGIGTAPRAAPEEI-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*..*** : * : .. . : . .*..: : . *..:* :*.*: . . *..: :*... :. * .* . :. :*: .:..**. ...* ** *** :** * : :.* .: * **:::* ****: . .*.* * ***: . * ::*:. :* * :: *: * : :. * *:*.: *::: :** ***** .:.::* *: *. .. . : . :. *:**:::** . *: *: :. *: *.: .**.*:...::* * ::: . :*.:. * *:* *:* :****. :: : *: :* :. .* * *: *:* : .:: * : :::. .. . .* . . .: . :. : .*. :* .* : * : :**::.: . .:::.:::. .. :.: :.:::.: .*:.:*:. ** * **.:.**.:.. :*. *:****:**..::*.:*:*:*****:** *****.. . * ..: ***:*. ** .* . * **:: .. *: : *: *::****: **.*:::*. :***:.* . :: :.:.*** ..:*.* **.. *: **.*:: .: *:.: * : *..*.*.** :*:. :*.. : *: : .. * *... : *::. .. ::: :: : :: * ..* .:. *.::::*. ::* :: . . :. .:: ::** .*.. : * ::* *: ::*: .** . :.* :: .* :: .: * .*. * . . *.: * *.. : *.** **: *.* . : *.: :: :*::* :* :***:*::*:::******:*.:: **.****::.*::**:*: . ** ** *:* *:.*******:.*:*********:*:..* *:..*::****:********:********::.:** * * **** *****:*::.** .: : .** :*.:*: :**. * .* *:.:* * :: : . . * * .**.: . * : *: :: * .:. .:: *.. ...* . *:. ", "identical_positions": 322, "similar_positions": 452, "identity": "21.76%" }, { "cls_id": "homologset.agr.MGI:2444268", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XG69-1", "uniprot_id": "F169A_MOUSE", "id": "Q5XG69-1", "name": "Soluble lamin-associated protein of 75 kDa", "aln": "---MAFPVDLLDNCTHEELENSSEDYLSSLRCGDPEHPECFSSLNITIPVSLSNVGFVPLYGGNQTQKILALFAPEDSLTAVALYLVGQWWAIDDIVKTSEPSREGLKQVSTLGERVVLYVLNRIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAVGFYSVKPTGSLCASFLTQNYQLPVLDTMFIRKKYRGKDLGLHMLEDFVDSFTEDALGLRYPLSSLMYTASKQYFEKYPGDHELLWEVEGVGHWHQRVPVTRALQREAIKATDVSQYEATRPVSGEYGLAAVPEHEPGLDDTQSS--ELQIHSLKDAFASTSEGPEKTPVSTRTRSSHLKRPKIGKHFQDSEFSSSQGEDENVAKTSPTASVNKIEYAARTSESSEEFLEEEPEQGVIDFEDESGDKDAQPALETQPRLQKQDGDKDSALEPVNGEVMDAALKPSLTTEDEDSTSEGLEEDLKVPPFNSSGEPGNPVPLVAESSKVPEATLAKTSP-DTDSEMLIDQSPSDDKGHTEENLSPVSKKKTLLGSSDNVATVSNIEKSDGNFPNSVVPEFPEEPVSQNLSPNTTSSVEDQGEEGAPEAQEPS--ATQSSLIEVELEDAPFPQNAGQKSQSEEQSEASSEHLEQFTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPGKKKAKLT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G2A6-1", "uniprot_id": "A0A8I6G2A6_RAT", "id": "A0A8I6G2A6-1", "name": "", "aln": "MQRMAFPVDLLDNCTHEELENSAEDYLSNLRCGDPENPECFSILNFTIPVSLSNVGFVPLYGGNQTQKILALFAPEDSLTAVALYLVGQWWAIDDLVKTSEPSREGLKQVSTLGERVVLYVLNRIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTGSLCASFLTQNYQLPVLDTMFIRKKYRGKDLGLHMLEDFVDSFTEDALGLRYPLSSLMYTASKQYFEKYPGDHELLWEVEGVGHWHQRIPITRALQREAVNVTEISQYEAKRPVSGEYGPAAVPECEPGLGERQCR--ELQIHSLKDAFASTSEGPEKTPVSTRTRSSHLKRPKIGKRFQESEFSSSQGEDENSAQTSPMASVNKIEYAARTSESSEEVPEEEPEKRVVECEDGSSDKDARPALETQPRLQKQDGDRDSALEPVNGEVTDAALKTSLAAEENDSSSEGPEE--EIPPLTSSGETGPPVPRAAESSKAPEATLDQTSP-VTDAEMLTDEGPSNDKGHTEENLSPVSKKKTILGSSDNVATLSNEEKSDGDFPNSVVAEFPEEPVSENVSPNTTSSVEDQGEEGVPEAQEPS--ATQSSLIEVELEDVPFPQNAGQKSQSEEQSEASSEQLEQYAQSAEKAVDSSSEEIEVEVPVVDRRSLRRKAKGHKGPGKKKAKMT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y6X4-1", "uniprot_id": "F169A_HUMAN", "id": "Q9Y6X4-1", "name": "Soluble lamin-associated protein of 75 kDa", "aln": "---MAFPVDMLENCSHEELENSAEDYMSDLRCGDPENPECFSLLNITIPISLSNVGFVPLYGGDQTQKILALFAPEDSLTAVALYLADQWWAIDDIVKTSVPSREGLKQVSTLGERVVLYVLNRIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTGSICASFLTQSYQLPVLDTMFLRKKYRGKDFGLHMLEDFVDSFTEDALGLRYPLSSLMYTACKQYFEKYPGDHELLWEVEGVGHWYQRIPVTRALQREALKILALSQNEPKRPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKKKAKLT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******:*:**:*******:***:*.*******:***** **:***:*************:**********************..*******:**** ********************************************************:**********:*******.**********:********:******************************.***********************:**:*:********:: :** *..**:***** *:*** *. : *. :* *.************ :**.***:***.:********:**:***********: ::** **:**:* :**.******. *****: :: ** *.*:**:*******: :****:::* ***:***: * :**.** :*::**:** :* :: *:.** :. ** ..**** **. ..:* .*:*** *:..*::*** **:** :.:**: *********:** *:***.*****:.**.*****:*:*******:*******..*.**.* .***********.**.******.***********:*:*::************************.***********.*****:*", "identical_positions": 498, "similar_positions": 117, "identity": "74.0%" }, { "cls_id": "homologset.agr.MGI:2444269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q53E76-1", "uniprot_id": "QTMAN_RAT", "id": "Q53E76-1", "name": "tRNA-queuosine alpha-mannosyltransferase", "aln": "MS-----ILIIEAFYGGSHRQLVELLREEV--DDCVLYTLPAKKWHWRARTAALYFSQSVPSSEHYS--------------------------------------------------------LVADVVVFNSNFNMESFLTSIGKFLKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHK-IAHLRRMLSLIGNDAAALSVTLPPQPEQRLSKKSLENFESKSDEHPGLD-TEQETLDT-----PTILKSVSLPVS-------EENPALGHSTFLCGAE-DQQRPLHITWPHRWEHDKDPETFLKVLMHLKELRLNFYVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPSKEDYFRVLCTADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLKSFCERPDIIRKH----LYKGEVAPFSWAALHGKFRSLLTTEPREDL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BW56-1", "uniprot_id": "QTMAN_MOUSE", "id": "Q8BW56-1", "name": "tRNA-queuosine alpha-mannosyltransferase", "aln": "MS-----IVIIEAFYGGSHRQLVELLREEL--DDCVLYTLPAKKWHWRARTAALYFSQNIPSSEHYRTLFASSVLNLTELAALRPDLGKLKKILYFHENQLVYPVKKYQERDFQYGYNQILSCLVADVVVFNSSFNMESFLTSIGKFLKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHK-IAHLRRMLSLIGDAAASQSVAPCPQPGQRVSEKSPENCESKSDEHPDLD-AEQEALDN-----PSVHKSGSLPVS-------KENLPLDPSTLLCGAE-DPQRPLHITWPHRWEHDKDPETFLKILMSLKQLNLNFHVSVLGETFTDTPDIFSEAKKALGSSVLHWGYLPRKEDYFRVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKALVYPEIFPAEYLYSTPEQLSKRLKSFCKRPDIIRKH----LYKGEVAPFSWAALHGKFRSLLTTEPREDL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4AE62-1", "uniprot_id": "QTMAN_HUMAN", "id": "Q4AE62-1", "name": "tRNA-queuosine alpha-mannosyltransferase", "aln": "MS-----ILIIEAFYGGSHKQLVDLLQEEL--GDCVVYTLPAKKWHWRARTSALYFSQTIPISEHYRTLFASSVLNLTELAALRPDLGKLKKILYFHENQLIYPVKKCQERDFQYGYNQILSCLVADVVVFNSVFNMESFLTSMGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHK-TTHLKKMLGLKGNGGAVLSMALPFQPEQRDSEDLLKNFNSECDTHCGLDTARQEYLGNSLRQESDLKKSTSSDNSSSHHGENKQNLTVDPCDILGGVD-NQQRLLHIVWPHRWEHDKDPESFFKVLMHLKDLGLNFHVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPSKDDYFQVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQNFCKRPDIIRKH----LYKGEIAPFSWAALHGKFRSLLTTEPREDL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568B7-1", "uniprot_id": "QTMAN_DANRE", "id": "Q568B7-1", "name": "tRNA-queuosine alpha-mannosyltransferase", "aln": "MS-----VLLLEAFYGGSHKQLLDLLKESV--EDCVSFTLPAKKWHWRARTSALYFMQAVPANSSYRVLFTSSVLNLAELVALRPDLGHLKKVLYFHENQLVYPVRKSQERDFQYGYNQILSCLVADVVVFNSSFNMESFLSSISTFMKTMPDHRPKDLERLIRPKCHVLHFPIRFPDVTRFLPAHKRLRHPVRCDDIHAP--AAKSHIQTSSPSSYPDVEPPEKMLNVAGTN-----QSHEPTS--------------------------VTPHQETASPLCGHEGEKLRPLHIVWPHRWEHDKDPQLFFQTLLKLKDRQLSFEVSVLGETFTDVPDIFSEAKEQLVDHIQHWGFMPSKEDYLKVLCQADVVVSTAKHEFFGVAMLEAVHCGCYPLCPKALVYPEIFPATYLYSTPEQLCKRLQEFCKRPQLARQH----VVQVSLSSFSWDSLGDNFRSLLKADSGRMFTDKHMA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXN0-1", "uniprot_id": "QTMAN_DROME", "id": "Q9VXN0-1", "name": "tRNA-queuosine alpha-mannosyltransferase", "aln": "MSCAKPHILIIEPFYGGSHKQLIGALIEGLNHGDSEIFSLPAKKWHWRARTSALHFAQLIPRDHAFRVLFASSVLSLAELIGLRPDLAACRKIVYFHENQLIYPVREVKQRDCQYGFNEILSCLAADMVLFNSQFNCNSFLDNVQPFLNMQPDFKIKHIREQIEKKCQVLYFPVNFER----FPIRK----------------------------ECVKGETAEDLD--------------------------------------------------------------EKCIHLIWPHRWEHDKNPKLLVDTLCQLHERQVDFKVTICGESYQEIPEEFEHIQEKLGSKLVNFGHLE-REEYLKTLLTGDIVISTADHEFFGVAMLEAAFCGCYPIAPNKLVYPEIYPKENLYNTSNALTKKLYNFCRMPRVFRKQRDQFFENFNFDRFSAKELVPKYLDIFNKHIADEQS-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ::::*.******:**: * * : *. ::************:**:* * :* . : *.**:*:*** ** :*** .: *:: **.: *.:. *. **:*::**:.* :* :* . . . :. : :*: *********:*: :.. * *:: :.* *:: **:: : *: *.. :: * . : ::*.: :::*::.* .*:*:***.***********..*****:.*: ******:* **.*.: * *:* .**. * : *:: . : .. ** * :: .::. . ", "identical_positions": 121, "similar_positions": 106, "identity": "25.37%" }, { "cls_id": "homologset.agr.MGI:2444273", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZYN4-1", "uniprot_id": "A0A8I5ZYN4_RAT", "id": "A0A8I5ZYN4-1", "name": "", "aln": "---------------MSGSGAAPGPGSGSSP------------------------------------AACRFAHYFVLCGIDADSGLEPDELA--------------------GENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQ-----------YSSVYASSSCSMDS-LASSIDEGDATSLLKLQR-YNSYDINRDTLYVSKSICLITPLPFMQACRKFLLQLHKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYG-VYEP------VICQRPGPN-ELPLSDYPLREACELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEG-------------------------------------SLHCSESATKLKNMVLKDLANDKK--NGNVPTNNVSVYELLKGS---ETIARLQALAKRTG--------VTVGKIDFPAS-----------------LSEKEKDLKLQCEEADLRDSQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTSREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEK-DPLLRVFDSRIEKMRLYNVRAPTLRTSIYQKCSSLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPANNNRWVSRSTTAQRRKERLRQNAEHIGLDSDLREPSGELLVCQNSMAFWEWDQGPTPPARLPKKSFSECCLKYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLLVKQGKSALWSHLIQFQDREEKQ----------------------------------------------EHLTDSPVALGPER-RKSDSGVMLPTLR---VSLIQDMRHVQNMTEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGVDDGSLERILIGELMTS-ASDEDLGKQC--RTPPQQKSPTTTRRLSITSLTGKPAKPNAGQIQEGIGEAVNNIVKHFHKPEKER--GSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFESTDQILDNEDDM----------------LIQKPSCKTFCHYVNAVNTAP-RNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPAITRMYEENALLRDHMTVNSLIRILQTIQDFTIVLEGSLIKGVDV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2RSQ0-1", "uniprot_id": "DEN5B_MOUSE", "id": "A2RSQ0-1", "name": "DENN domain-containing protein 5B", "aln": "---------------MSGSSAAPGPGSGSSP------------------------------------AACRFAHYFVLCGIDADSGLEPDELA--------------------GENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNKEPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQ-----------YSSVYASSSCSMDS-LASSIDEGDATSLLKLQR-YNSYDINRDTLYVSKSICLITPLPFMQACKKFLFQLHKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYG-VYEP------VICQRPGPN-ELPLSDYPLREACELLGLENLVQVFTCVLLEMQTLLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEG-------------------------------------SLHSSESATKLKNMVLKDLANDKK--NGNVPNNSVSVYELLKGS---ETIARLQALAKRTG--------VTMEKIDLPAS-----------------LSEKEKDLKLQCEEADLRDSQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEK-DPLLRVFDSRIEKIRLYNVRAPTLRTSIYQKCSSLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPANNNRWVSRSATAQRRKERLRQSSEHIGLDSDLRE-------------------------------------KYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLLVKQGKSALWSHLLQFQDREEKQ----------------------------------------------EHLTDSPVALGPER-RKSDSGVMLPTLR---VSLIQDMRHIQNMTEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGVDDGSLERILIGELMTS-ASDEDLGKQC--RTPPQQKSPTTTRRLSITSLTGKPAKPNAGQIQEGIGEAVNNIVKHFHKPEKER--GSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFETTDQILDNEGDV----------------LIQKPSSKTFCHYVNAINTAP-RNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPAITRMYEENALLRDHMTVNSLIRILQTIQDFTIVLEGSLIKGVDV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZUT9-1", "uniprot_id": "DEN5B_HUMAN", "id": "Q6ZUT9-1", "name": "DENN domain-containing protein 5B", "aln": "---------------MSGSCAAPGPGSGSSP------------------------------------AACRFAHYFVLCGIDADSGLEPDELA--------------------GENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQTDNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEH-----------YSSVYASSSCSMDS-LASSLDEGDTTSLLKLQR-YNSYDISRDTLYVSKSICLITPLPFMQACKKFLIQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYG-VYEP------VICQRPGPS-ELPLSDYPLREAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLVQFGIPPEG-------------------------------------SLHCSESTSKLKNMVLKDLVNDKK--NGNVCTNNISMYELLKGN---ETIARLQALAKRTG--------VAVEKMDLSAS-----------------LGEKDKDLKLHCEEAELRDYQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEK-DPLLRVFDTRIDKIRLYNVRAPTLRTSIYQKCSTLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTSNNRWVSRSATAQRRKERLRQHSEHVGLDNDLRE-------------------------------------KYMQEARSLGKNLRQPKLSDLSPAVIAQTNCKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLIQFQDREEKQ----------------------------------------------EHLAESPVALGPER-RKSDSGVMLPTLR---VSLIQDMRHIQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGIDDGSLERILIGELMTS-ASDEDLVKQC--RTPPQQKSPTTARRLSITSLTGKNNKPNAGQIQEGIGEAVNNIVKHFHKPEKER--GSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKVVAYFETTDQILDNEDDV----------------LIQKSSCKTFCHYVNAINTAP-RNIGKDGKFQILVCLGTRDRLLPQWIPLLAECPAITRMYEESALLRDRMTVNSLIRILQTIQDFTIVLEGSLIKGVDV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NXD8-1", "uniprot_id": "DEN5B_DANRE", "id": "Q6NXD8-1", "name": "DENN domain-containing protein 5B", "aln": "---------------MSAT------MSGSGS------------------------------------APCRFAHYFIVCGLDDETGLEPDALAALYQWLEADRQGKDPEATAAGENFDQSPLKRTFKSKVLAHYPENIECNPFDQDAVNMLCMPKGLSFRTQRDSLAPHFHSFLITREDGSRTYGFVHTFYEEVTSPQICSAMQTLHQMHQAEHNTSAQNCTSSSSSSSSSSSSSSMDS-LSSSLDDVDSPSAHGGRRTCEGYDSIRDTLYVSKAMCLIAPMPFMHACKRFLAQMHRAVSCSPPPPLPLESYIYNVLYEVPLPASGRSLKFHG-VYEP------ILCQRPGVG-ELPLADFPLADAFRLLGVENLVQLFTCVLLEMQILLYSQDYQRLMVVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHCIELPEDFPQFPNRSEFIQELSEVLLSFGQSPEGGSSSPEP---------------------------AVMSLQTSVLEKELKSTSLRELVDDKT--NGNLGGEALDVLELLQGN---PTLERLQALAKRTG--------VKVARLEALAAGQ---------------KGDEGVGGRSPVEEEELRNAKLNVQLREVFAARFATMFADYESFVIQNSPDLESWLTNREQMHNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIMSQWEEK-EPLLRVFDGRIEKARLYNVRAPSLRSSVYQKCTFLKESAQAIEQRLRKIDHTAIHPHLLDMKIGQGKYQQGFFPKLQADVLASGPTSN-KWSNRTCSTQRRVERHRQQNEHLVLDNELKE-------------------------------------KYMQEARNLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECKMKTKRMLVEKMGREAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQAREEKN----------------------------------------------EQQLESPVSNGQER-RKTESSVGLPGLR---VSVIQDMRHIQNMAEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQALTKKLYKRYAFLRCEEEKEQFLFHLLSLNAVDYFCFTSVFTTIMIPYRAVIIPIKKLSNAMTTSNPWLCVSGELGDSGILQITKNILEMTFDCQNLGKLTTVQLGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERVLIGEFVVP-CGDDEGGRGS--KTPPLQRSPSQIRRISITSLTGKGNKPTTVQIQESIGEAVNNIIKHFHKPEKER--GSLTVLLCGEGGLVWALEQFFHHGFRSARIFQKNVFVWDFFERIVAFMENRDQTGDLQESP----------------EPLSLNSESLCRYVNAINNMP-RNIGKDGKFQLLVCLGARDRLLPQWLPLLAESPVITRMYEENALLRDKLTVSSLLGVLETLHDFPITLETSLTKSVEL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0E1-1", "uniprot_id": "Q9W0E1_DROME", "id": "Q9W0E1-1", "name": "", "aln": "MTTRENVVSSRLSKLMLSSGSGNGSGNGSGPNIQVAPSSTLVQSPTSPGEQSQSQSELNQLKRDADPQFSRFADYFVICGLDLDTGLEPDRFA--------------------GDNLHCSPLDRAYKSKPLAHYPENVPWNPFDAHGICMLSLPQGLRFRTQKHCIEPRFHSFATTREDGKRCYGFSLVFYEEIRNRNICGAIHTLQSMFITELS---------NGQQTHSLSRVKQDGPVSRSLPRHFKVAGQAPQSAQSYYDINKDKLYVAKSITLICQAPYAFAAQMFLKNLYRCLPRQPGAGISLESYVYNILYEVMLPQPGKSIRVYLPPTEPHLPPIALILQRPLLATELPLLDFPLRLLFKYLGVECVIQLLTCVLLENQVLLRSTDYQRLMIVGECITSLLFPFVWPHVYAPILPAALHHFLDAPVPFVMGLHAECEAAH---KIGSEATLCFVDIDKKHIQLPEELPVFPHKVDFMAEIGSVLDKFEIERDRDQEPSFRNGYVGRGAGGGVSGSGSSGSGGVDAMISSCTLPTGLQAARRSKERFQQMQETVYTLSGSPGGGVVDYQPLIAHPSRIDHVPRIADFLRRKGGIRGAGSPVGSPTVSLSSSPVGIYHDVDAVDATMPVSTRRAEKQKLSPVDQYYQDLRINNSVREIFLNRFVHMFHAYEYFVIYPNQARDEWISNRETLQNFDKSSFLSDQPEHHRAFLSRFLESQMFATLIDNKILAMWESQPDEQLQLFDQRVKLLRRRHG-ENMIAATSYEPCVLSQDSQQGFEKRLNCIDIEVTPP--SEILANRAAYFR-SFPLLEKGVLNQ------ECASRGNSLRRVKNGNKWRAREISLDQKPGS----------------------------------------NAINRLSANLTT---ADVSPALIAQANWTFVERLLKDIKSKTKRMLLEKMGNEAVALGLKGD---GIEENTLIASMCDLLEKIWSHGLQNKQGKSALWAHLQAYLEMQEARGAGDSSGTEQTPPVSSSPGGKMTIATASPALAWNAMRKRMDYLSTFQTDFDSPPSPNRSRSRDRNKFVGLEQLCPLPESLEFDVKNVLAMADIKTHIGYTRAWVRLSLEKKLLSRHFRTLLSDEALLRSLYKRSAFLRCEEEKEQFLYHLLTLNTVDYFSFTNIYPTTKLPYRVVIFPSRKYGSYHTSSNVWIMVSGTMNETQRVPVPKGSLEFIFHYKNLGLLTTMRIGHDNSGPSHKWLVEQVVMRNEVTGHTYKFPCGRWLGRGVDDDSTERLLVGQRVLTNAKNAELVPGSDTRTPPRTRSPSVQRQETLAPS----------EIQHQLGNCVNVLVKWHYKPSRDRDVGTLTNLLCGDDGLVKCLEQVFLCGFRSARFFGRNLYIWDYFTKIKELFEHNLQMELEDSSSSLDSSFSNGSGSGGNSLQRREISSIWRLYVQLMDEINGTALGKDGKFQLLICLSLREHLLTRLIKPMALTKVTHEMYEEESFLRRRNLLTFLIQILEPLDDCHIVLENSITQGIRIASQC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: .**.. .***.**::**:* ::***** :* *:*:. *** *::*** *****:*: **** ..: **.:*:** **** . *:**** *****.* *** .****: . :** *::** .*. :* .. : * . *. :: *: : : . ** :*.***:*:: ** *: *.: ** ::::.:. . . :.****::*:**** ** .*:*::.: ** :: *** **** *:** . **:* ::*::****** * ** * ****** *.* **:***** * ***.*****:* ********::***::: : : :: .**.*******:: *:***::* **:: :*: *:..** .* : :* . . .. :::: : .*. :. *: : *: : :*.* * :. :: . : : :: ::* .:**:* **. ** ** *** :.*::.** ::****:******** : .***:*:*:*****:*****:: **.: : *::** *:. * : : :: *: * ::: *.:*:** :* . * :: .:. * : ** *: .** . .* : :* : : ..: **.. . : . *. ** :*:***:***:* .*** ***: : ******:****.*** ** *:********:*****:****** ********:** : :* . : :** : . .* *. :. * * * *: *:::: *::***.:* :***:**********:*:: ***::.* :.**** ********:****:***:**:****.**.::.* :*** **:* :* .. :** *: *** :.:: : :.*. **: *. :*** ***:::****** ****: *::***:*****:********:*:**.* **:*:*: : . . : : . :*** :**: *: :::. :**. :*:.** ::* .:**.::* *:** ****:.*** .***.* **:***:* :*:::**:. : :* * : . .. **: :: :*******:*:**. *::**.: : :* . .****.::** : :. *: :*:.:.* *.** *: :.: : ", "identical_positions": 507, "similar_positions": 371, "identity": "32.77%" }, { "cls_id": "homologset.agr.MGI:2444274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZU64-1", "uniprot_id": "CFA65_HUMAN", "id": "Q6ZU64-1", "name": "Cilia- and flagella-associated protein 65", "aln": "MFTLTGCRLVEKTQKVENPSVSFASSFPLIPLLLRGKSVQKKQAESKSQIKLHTQSAPFGLCPKDMMLTQAPSSVVRSRNSRNHTVNSG--GSCLSASTVAIPAINDSSAAMSACSTISAQPASSMDTQMHSPKKQERVNKRVIWGIEVAEELHWKGWELGKETTRNLVLKNRSLKLQKMKYRPPKTKFFFTVIPQPIFLSPGITLTLPIVFRPLEAKEYMDQLWFEKAEGMFCVGLRATLPCHRLICRPPSLQLPMCAVGDTTEAFFCLDNVGDLPTFFTWEFSSPFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQLLVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAEDQAFSCPTAHGIVLPGEKKCVSVFFHPKTLDTRTVDYCSIMPSGCASKTLLKVVGFCRGPAVSLQHYCVNFSWVNLGERSEQPLWIENQSDCTAHFQFAIDC-LESVFTIRPAFGTLVGKARMTLHCAFQPTHPIICFRRVACLIHHQDPLFLDLMGTCHSDSTKPAILKPQHLTWYRTHLARGLTLYPPDILDAMLKEKKLAQDQNGALMIPIQ-----DLEDMPAPQYPYIPPMTEFFFD-----GTSDITIFPPPISVEPVEVDFGACPGPEAPNPVPLCLMNHTKGKIMVVWTRRSDCPFWVTPESCDVPPLKSMAMRLHFQPPHPNCLYTVELEAFAIYKVLQSYSNIEEDCTMCPSWCLTVRARGHSYFAGFEHHIPQYSLDVPK-LFPAVSSGEPTYRSLLLVNKDCKLLTFSLAPQRGSDVILRPTSGLVAPGAHQIILICTYPEGSSWKQHTFYLQCNASPQYLKEVSMYSREEPLQLKLDTHKSLYFKPTWVGCSSTSPFTFRNPSRLPLQFEWRVSEQHRKLLAVQPSRGLIQPNERLTLTWTFSPLEETKYLFQVGMWVWEAGLSPNANPAATTHYMLRLVGVGLTSSLSAKEKELAFGNVLVNSKQSRFLVLLNDGNCTLYYRLYLEQGS-----PEAVDNHPLALQLDRTEGSMPPRSQDTICLTACPKQRSQYSWTITYSLLSHRD----NKAGEKQELCCVSLVAVYPLLSILDVSSMGSAEGITRKHLWRLFSLDLLNSYLERDPTPCELTYKVPTRHSMSQIPPVLTPLRLDFNFGAAPFKAPPSVVFLALKNSGVVSLDWAFLLPSDQRIDVELWAEQAELNSTELHQMRVQDNCLFSISPKAGSLSPGQEQMVELKYSHLFIGTDHLPVLFKVSHGREILLNFIGVTVKPEQKYVHFTSTTHQFIPIPIGDTLPPRQIYELYNGGSVPVTYEVQTDVLSQVQEKNFDHPIFCCLNPKGEIQPGSTARVLWIFSPIEAKTYTVDVPIHILGWNSALIHFQGVGYNPHMMGDTAPFHNISSWDNSSIHSRLVVPGQNVFLSQSHISLGNIPVQSKCSRLLFLNNISKNEEIAFSWQPSPLDFGEVS-VSPMIGVVAPEETVPFVVTLRASVHASFYSADLVCKLYSQQLMRQYHKELQEWKDEKVRQEVEFTITDMKVKKR----------TCCTACEPARKYKTLPPIKNQQSVSRPASWKLQTPKE-------EVSWPCPQPPSPGMLCLGLTARAHATDYFLANFFSEFPCHFLHRELPKRKAPREESETSEEKSPNKWGPVSK-QKKQLLVDILTTIIRGLLEDKNFHEAVDQSLVEQVPYFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVKEEQEQDEKEAIRRLPAFANLQEALLENMIQNILVEASRGEVVLTSRPRVIALPPFCVPRSLTPDTLLPTQQAEVLHPVVPLPTDLP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3V0B4-1", "uniprot_id": "CFA65_MOUSE", "id": "Q3V0B4-1", "name": "Cilia- and flagella-associated protein 65", "aln": "-----------------------------------------------------------------MLIQKNQCHITRTRENCDCTMNTVNEDLCLSASTLGS-------------SSVTTQLVDPLDRKICLIRRQNDVKKRVIWGIEVAEKLHWKGWELGKETTRTLVLKNLSLKTQKMKYRPPKTKFFFTIIPQPIFLSPGITLTLPIVFRPLEAKEYTDQLWFEKEEGVFCVTLKATLPCYKLDC-PSSLQLPMCALGDTVETWFCLNNVGDLPTFFTWEVPAPFQILPTTGLLEPGLGCKIKVTFEPLIAVIHEVEALCWYGKGNKQKNSINIQAAAKCAQLLVSIKHKGLEDQDQEGFQKVVHFGYVSVGSVAERQIRLYNPSAVNAPFKIEMAEHVLTKDPSFSCSTSQGIVPPGEKKCLSLFFHPKTLDSRAIDYFSIIPSGCATKTLLQVVGFCRGPDAVLQHSCVNFHWVKLGERREQTLWIENQSDCQAHFQFDIDC-QESVFSIRPAFGTLAGKTRMTLHCAYQPTHPIISFRRVACLIHHQDPLFLDLIGTCHSDSIKPAILTPQHLTWYRTHLARGLTLYPPDILAAMLKEKKLERDEDGALILPIESLPMQELEDLPDQKYPNIPPMTEYFFD-----GTRDLAIFPPAVCLEPIDVDFGACPGPEAPNPVPLCLRNYTKGKITVVWTGRSDCPFWVTPVTSDVPPLKSIALRLYFQPSSPNCLYAVELEAFAVYKVLQCYSNIEEDCTVVPSWCLKVRARGHSYSPALEHHIPHYSLDSPQ-TFPAVSPGKPSYRSLFLVNKGSMLMTFSLAPNSSSDITLRPSSGLIGPGAHQVFLISTYPKGTSWRQHIFYLNFNFYPQYLKEVSMQSREEPLDLKLDTHKSIYFKPTWVGCSSTSNFTFHNPSRLPLQFEWRVSQEHQKVLAVQPSKGTIHPNENLTLTWIFSPLEEIKYLFRVGIWVWEARQSQKTKPQATVHYRIRLVGMGVTGCLSAKPVELDFGNVLVNSQEVKPLVLLNDGNCTLYYRLVLEQHR-----PKGLHSDPCALEFDHSEGTMPPHSQDTIYLTARPKVRSQYSWTISYCLLSQRAPPTNSMDGKKKALCHVSLAAAYPLLSVLDICSMGSTEGITRKHLWHLFSLDTLNSYLARDPTAKELTYKVPTRHSMSRTPPIFTPLKLDFNFGAAPHNALPSVVLLVLKNCGLVPLDWAFLFPSDQQLDLDLWVEQEDLNSNELHQMRAEDNSLFSINPKTGSLNPGQEQMVEFTYRHLFVGTDRLSVLFKVSHGREILLQFIGVTVKLEQKYVHFTSTIHQFIPVPIGDTLPPRQIYELYNGGSVPVTYEVQVSVLSKVQEKNFDHPIFCCLNPKGDIQPGTTARILWIFSPIEAKTYTVEVPIHIIGWNSAVVCFQGVGYDPCVMGDTAPFHSISSWDSSSISSRLMVPGQNVFLSQSHISLGNIPVQSKCSRLFFLNNISKNETIVFTWKPRSLDFGEVT-VSPMEGEVGPEEGAPILVTLKASVHASFYSIDLICKVYQRELMRQYHKELQEWNEEKARQEVEFTITDRKVKRR----------AYCAAHEPPKKYKTLPPITNQPPLNRPATWNLKLAKK-------ETSWPCPQPPVPGLLCLGLTARAHATDYYLANFFSEFPCHFLYRELPKKKSSKEESKSSEE-LPDKKGPVSR-QKQQLLVDCLTSIIRGLLEDKNFHNAVDQNLVEQVPYFCQFWNEQSARFLAQKSSLYLVPILSLPP-SYEGRKSKEQEED-------LFGKMPGGQEDDEEEEEDEEEAEEEEEEIEEEMS-------KDEEDIDKDAKMTWSGIKVTET--SQHSLQWQWQQDLKTIIKEETESDEKEAIGRLPAFANLQEAILENMIQNILVEASRGEVVLTSRPRIIALPPVSMHR---TDNLLQMSQGDVLCSGMQHPDCLLVSASSPSNMTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1RHF7-1", "uniprot_id": "A0A8M1RHF7_DANRE", "id": "A0A8M1RHF7-1", "name": "", "aln": "------------------------------------------------------------------MLTDHPVNPLSSRIPFGVPNNPH------------------------------RKRVSSLKSGFIQKRPQN-----CFFGVETWAELVWEYWEPGLEYTKSLVLKSIHGKLQKLTFRPPSSKLFSTPFPQTILLSPGTSFSLPVTFHPLEKCEYVDAIEFECKEGTFQVCLRAVIPHHALDV-PETVILPPCAAQQCSQTSFFFRNSSKLQTVFRWFVDPPFQLSPETGQLNPGEECRVTVEFRPQQALVYQAEASCAFGDDGESRCAVLLRGLSKYPHLQISS-------TGQEEGCKVLDFGSVAVGEFLEKHFEIHNPSTVSTAFSLSWMRRPTLMESVFRCEVYEGTIAPYSVLKVPVCFSPLTVESISVDYIRLTCPGAVNEELLKVSGTCIGPIVSLSTSVLDFGCVEEGSEMSHNVQIINSSAVLAHYQFDMDTGGHSVFSVDKPCGILGGSSKLNLRVKFRPHCSVAYHKTVTCLLMHREPLFLDLIGTCHSEQLKPAILNPGHLSAYRLNLLQGLTCYPPDLLSTLLEEQKLKVDDSGALVIQEFP----ADTVYPTRLFNPRSPIEEYFHVNLAPEAETELGNNSSKFPVHHVTVQPSQLLFYDGPASKSVSITNHTKGKICVMWSPGAKSSFSIFPLSCELGPLKTTAFRVTYSPNQQNMFHATQLECFTFYKVLKNHR-IVEDQTLCPPWCLTVRVTGHSFQPGKEPFVPKFSLQHSQVVFPALKR--VSYRTVLLQNTGDLPLIFRLDPEECPSVCVLPPSGLVPPGSHQILTLRCSPSPDHPSRIPLTLHLNASPNHTQVLNVVAVAEKLSVSVEGDGRLFFQPTAVNSCSEQTLQVKNTSTVPLEFKWRLCRSDQTVLTVLPDTGVLQPNECKVQKWSFTPKEEMMYNMRPCLTFWPVQAPQIEK----SRFTVKAIGFASKCSLQAEQPVIDLGEVLVGSCKAFDFPLLNNSPCAVSYSLTTQQCISVTGFPEEMTQDPQVLEMENAKWTIPADCRILIRCTVKPALRAHYCWTIGYHVLNVSG---STGEDQPQTICNVQAEGVYPSLEVMDIRSCGGLDGLSKLQLWRLFNLDTLNSNLRRDPSPSELTFRVPTRHSLRRCPSIFTSAIVDFSFSASPLGSEPSSVLLLFKNPGSIPVEWSFLFPEDQQIELDYWAESGDFSASELHLMKIQDHRLFSISPRSGRLQPGQQKTVQFMYRHDFVGTDRLPVLLKLSHGREILLNFIGVTVERDRRYIHLSSNRHIFAPVPIGCFSPPKQVFELYNAGTLPLRYHMDTTPLEELMEENFSHPVLQCLNPAAEVKPGHSAMLEWIFSPLEAKTYTVDVPIHVVEGDSMFVTFEGQGFD---ERESEPIQIQNGGITVPSIQRISVPGQVVYLSEERVCFGDIPVCSRSTRILFLTNISNTDEVLYKWNITSTECKQTINIRPESGHLAPGQSVLCILTIQASGSPTFYQEDLICEITLLKMLAQYHKDLRQWEEETERQKYEFTITEKDMIQSNQLNKYTQEDAVFEKKTGTRKYKTLPPIRSSDQAVSCATAKPSRAEQRARQHTGQERRRRPELPRPALLHLGVTARSHSLLEYQTHFPTHFNTHYINRSRQPKDSSSGTAESFYH--PSELTPLGPGHERDIVTHLLTSLLQSLLDEPQFQQCLLEGDIEQVPYFTQLRP---------------APVLPTKT-------------------------QPHSSSDSQDHVQMSSVSNAALAETHPGHCN------------------------------TGDRPKTDYEQEALTELQEEIKIKAQESIRRLPEFCDLLEDILLNTLQNLMMEAFLGELVLTTRPRIIALPPTSSRRSSFGSNKQSSAESKKSKQQMRPLLTSPTPRVSDLKPEQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . :* . . *. : ...:. : : *: ::*:*. :* *: ** * * *:.****. * **:.:***.:*:* * :**.*:**** :::**:.*:*** ** * : ** ** * * *:*.:* : * * :: ** ** : :: * : * ..* *.* * . .***: * ** *:** .::.* *.* *::::.:* * :* ....: :: ::. :* .:* :* . * *:: ** *:** *:::.::***:*.:.* :. : * * . .* : * . :.: * * *::: ::** : .*...: **:* * * ** . *. ::* *: *.. .: : * *.* **:** :* .***:: . * * *.:::.*: ::* .: .: *:**: *::******:*****:. *****.* **: ** :* :*** ****:* ::*:*:** *:.***:: * : .*: *:*. . :: .. . :. : *: . :.* . .:.: *:***** *:*: :...* : * :.:: ***: *:*: :.* * :::.:**.*:.****: : * ** *: *.***.**. ***: .. * .:*::**: .: ***:. :**:::* *.. : * * *: ..: : *.***: **:**:: : *. : : *: * *:: : :.: : * *.:.:: . ::*:** *...* . : .:*.* :**:*:**:....:.:*:* *. * ::*** . .* *:* ** * :: : .* . . : :: :: :*.. . .*.*: : :*:***.* : : ***:. *:: * * :* *: : ..* .*:::.:: ::*. .: * *. * *::*.*** * :*. . .: : :* *. ..** *.::*: * *. :*::: :**:**.** *** * ***:. ***::******: : *.::*. :**.*.*:* : ** *:* :** * :.::*:**:*.**::::: *.*. ::.:.*** *: :*: ****.*::* *.***:: *:: * * *:***:*.**:*:********:******: :::*:*::*. * * *:*** **:*::****.*::*: *.::. *.:: *:**.**:: **** .:::** :* : *****:*******:****:: :* .: *:* *:: :: *:: .. . . .*: **** *:**:.::.:*:*** *:.:*::**.***:.: : :.*: . : :. : * * :.* : . ::*::** .:**. **:*:: ::: ****:*::*::*. **: *****: .: : : .:******** .. *: : . .:: : *: * *.:* **:***:*: : ::* :.* *:: *. :.:. ::: . *.: *:. ::::::.. **::::.**:: :*::.: :. :****** *: *:*. . ....::. : . : * . : . : :::*: . ::** : . :*:* *** *.:* * :* * :**:::** **:***:***:***** . * .. :.. : ", "identical_positions": 561, "similar_positions": 637, "identity": "28.36%" }, { "cls_id": "homologset.agr.MGI:2444277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RKR3-1", "uniprot_id": "ISLR2_MOUSE", "id": "Q5RKR3-1", "name": "Immunoglobulin superfamily containing leucine-rich repeat protein 2", "aln": "-MGPFGALCLAWALLGVVRACP-EPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFV--NVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHNLISNFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLEPGTFDALS-----------------------ALSHLQLYHNPFHCSCGLVWLQAWAASTRVSLPEPDSIACASPPELQGVPVHRLP--ALPCAPPSVRLSAEPPPEAPGTPLRAGLAFMLHCVAEGHPTPRLQWQLQ------------------------IPGGTVVLVPPVLS--KEEDGGDKVEDGE---GDGDEDLPTQTEAPTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGIYTCRAHNELGTNSTSLRVTVAAAGPPKHAPGTGEEPDAQVPTSERKATTKGR----------SNSVLPFKPE------GKTKGQGLARVSVLGEIEAELEE-TDEGEQMEGQIPADPMGEKHCGHGDPSRYVS-----------NHAFNQSSDLKPHVFELGVIALDVAEREARVQLTPLAARWG----PGPDGASGARRPGR----RPLRLLYLCPAGGGTAVQWSRVEEGVNAYWFRGLRPGTNYSVCLALAG--------EACHVQVVFSTKKELPS--------LLVIVTVSVFLLVLATVPLLGAACCHLLAKHPGKPYRLILRP-------QAPDPMEKRIAADFDPRASYLESEKSYPARGEAGGEEPEEVPE-----------------EGLDEDVEQGDPSGDLQREESLAGCSLVESQSKANQEEFEAGSEYSDRLPLGAEAVN------------IAQEINGNYRQTAG-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R4G0-1", "uniprot_id": "M0R4G0_RAT", "id": "M0R4G0-1", "name": "Immunoglobulin superfamily containing leucine-rich repeat protein 2", "aln": "MMGPFGSLCLAWALLGVARACP-EPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFV--NVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHNLISNFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLEPGTFDALS-----------------------ALSHLQLYHNPFHCSCGLVWLQAWAASTRVSLPEPDSIACASPPELQGVPVHRLP--ALPCAPPSVRLSAEPPPEAPGTPLRAGLSFLLHCVAEGHPTPRLQWQLQ------------------------IPGGTVVLVPPVLS--KEEDGGEKVDDGE---GDGDEDQPTQTEAPTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGIYTCRAHNELGTNSTSLRVTVAAAGPPKHAPGTGEEPDAQAPTSERKATTKGR----------SNSVLPFKPE------GKTKGQGLARVSILGETEAELEE-TDEEEQMGGQIPADPMGEKHCGHGDPSRYVS-----------NHAFNQSSDLKPHVFELGVIALDVAEREARVQLTPLAARWG----PGPDGASGARRPGR----RPLRLLYLCPAGGGTAVQWSRVEEGVNAYWFRGLRPGTNYSVCLALAG--------EACHVQVVFSTKKELPS--------LLVIVTVSVFLLVLATVPLLGAACCHLLAKHPGKPYRLILRP-------QAPDPMEKRIAADFDPRASYLESEKSYPARGEAGGEEPEEVPE-----------------EGLDEDVEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYSDRLPLGAEAVN------------IAQEINGNYRQTAG-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UXK2-1", "uniprot_id": "ISLR2_HUMAN", "id": "Q6UXK2-1", "name": "Immunoglobulin superfamily containing leucine-rich repeat protein 2", "aln": "-MFPLRALWLVWALLGVAGSCP-EPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFA--DVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALS-----------------------ALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLP--ALPCAPPSVHLSAEPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQ------------------------IPGGTVVLEPPVLS--GEDDGVG-AEEGE---GEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGR----------GNSVLPSKPE------GKIKGQGLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVS-----------NHAFNQSAELKPHVFELGVIALDVAEREARVQLTPLAARWG----PGPGGAGGAPRPGR----RPLRLLYLCPAGGGAAVQWSRVEEGVNAYWFRGLRPGTNYSVCLALAG--------EACHVQVVFSTKKELPS--------LLVIVAVSVFLLVLATVPLLGAACCHLLAKHPGKPYRLILRP-------QAPDPMEKRIAADFDPRASYLESEKSYPAGGEAGGEEPEDVQG-----------------EGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYSDRLPLGAEAVN------------IAQEINGNYRQTAG-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKG1-1", "uniprot_id": "Q9VKG1_DROME", "id": "Q9VKG1-1", "name": "", "aln": "-MSGLPIWIPLLALLAITAACPPEVCVCKWKGGKQTVECGGQQLSNLPEGMDPGTQVLNFSGNALQVLQSERFLRMDLLNLQKIYLSRNQLIRIHEKAFRGLTNLVELDLSENALQNVPSETFQDYSSLMRLSLSGNPIRELKTSAFRHLSFLTTLELSNCQVERIENEAFVGMDNLEWLRLDGNRIGFIQGTHILPKSLHGISLHSNRWNCDCRLLDIHFWLVNYNTPLAEEP--KCMEPARLKGQVIKSLQREQLACLP-------EVSPQSSYTEVSEGRNMSITCLVRAIPEPKVLWLFNGQVMSNDSLMDNLHMYYYIDETIGVSGAEEKRSEIFIYNVGAEDNGTFSCVGQNIAGTTFSNYTLRVIIKEPPVVNEVSFPRDYMNYIVASSAGGGIIFVVLLCTIVVKCKKTSEPAKQRKKCDQVTSIAGGTDSSTGSTQDTGMGMMKCASILNDGGDSMNGNPGLLLGDTLTPTKAANGAAGGGIILGNQMKQNLLLYATPNSAQQQLQLNVNLMGTGPGSPPLLLSNGHGLAAAYCSPPASLRNYQEKNPDLVNDAESVKHKLKTAVSLDGAGEYETQSDCGQYEGCYQLAAAPHPHQGHQHPHPGHPLMGRFAQAMTTLPRGMQLKPAPHQVDVHLNPVCFLGQDGSFAYDYSSAHMVQQPPQQQQQQQQVQPANNFYRTLPHNRLHKQQQFQAAAAAGGNVGVGGNPTLRYSLEAEFIQRGPTVSYEKYQLPNVRFTAEGYPQQQQQQQQQLQQQQQLQLQQQHQFPSPPEGYKSDLAVMPAPFQQWPSCLPGYRFAQSPTSLPAVATPPPAAVVATPPPPTSAVSTQSTATSTIPELDESEASSPRLEEAAGSAAPPAGEEESSDTAKLKQLNGPLADSPDEGYVGDGQETSDI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : ***.:. :** * *.* * .:* .:*. ::* ::***: ... .*.:*.* : **: * :: :: .::*::.:: :. *: *::* :****.* :...* . ::: *:* *.:. * : .* .*: *. * :*.:.* ::. : :* .:. :* :.*: * ::*.* *: :: * .. ...*.* * .*. *:* : * *.* * * . ::. * : * : : *:. . * *:: * :: :.*. .: :*. *: * : :. *. . . * .::. :... : :: : : .*: .* . : .. ..: :* .. :.*: :.. .. . * .::: * *. * *: : : :* . :: . : . ..* *:* .: * * * : :.:: * :: .* ...* *:: : . : * * . :**: * : : * * :*: :*. * * . *. . * : :** . . : ** : . .:.. : * .. .* : ..:: : * .*. * *: ::: : : *:.::.:*: *. .: : . *:. : . :.. .:* :.:. *:: .. * ** .* :. :::** ::.. ", "identical_positions": 128, "similar_positions": 273, "identity": "14.16%" }, { "cls_id": "homologset.agr.MGI:2444283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BH44-1", "uniprot_id": "COR2B_MOUSE", "id": "Q8BH44-1", "name": "Coronin-2B", "aln": "MTVTKMSWRPQYRSSKFRNVYGKAANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMT---------EALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKN-HRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPMIE--EEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGG-INRDPVLMSLKEGYKKSSKVVFKAPI----------------------------REKKSVVVNGIDLLENVPP-----------RTENELLR---------------------------------------------------------------MFFRQQDEIRRLKEELAQKD----------------------------------------------IRLRQLQLELKNLRNNP------KNC--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LMV9-1", "uniprot_id": "F1LMV9_RAT", "id": "F1LMV9-1", "name": "Coronin", "aln": "MTVTKMSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMT---------EALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKN-HRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPMIE--EEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGG-VNRDPVLMSLKEGYKKSSKVVFKAPI----------------------------REKKSVVVNGIDLLENVPP-----------RTENELLR---------------------------------------------------------------MFFRQQDEIRRLKEELAQKD----------------------------------------------IRLRQLQLELKNLRNNP------KNC--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UQ03-1", "uniprot_id": "COR2B_HUMAN", "id": "Q9UQ03-1", "name": "Coronin-2B", "aln": "MTVTKMSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNTRFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMT---------EALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKN-HRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPLIE--EEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGG-INRDPVLMSLKEGYKKSSKMVFKAPI----------------------------KEKKSVVVNGIDLLENVPP-----------RTENELLR---------------------------------------------------------------MFFRQQDEIRRLKEELAQKD----------------------------------------------IRIRQLQLELKNLRNSP------KNC--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TAY8-1", "uniprot_id": "A0A8N7TAY8_DANRE", "id": "A0A8N7TAY8-1", "name": "Coronin", "aln": "MTVTKMSWRPTYRSSKFRNVYGKVANREHCFEGIPITKNVHDNHFCAVNAKFLAIVTESAGGGSFVVIPVTQFGRIDPHYPKVCGHQGNVLDIKWNPFHDNIIASCSEDSSVRIWEIPDSGLTRSLT---------ESVLELYGHSRRVGLIEWHPTTSGILFSAGYDYKILIWNLEIGEPVKMIDCHSDVILCMSFNTEGSLLATSCKDKKLRVIEPRSGRVLQEANFKN-HKVNRVVFLGNIKRLLTTGVSRWNTRQIALWDQEDLSMPIIE--EEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEVTLEKPYLQYLMEFRSPAPQKGLGVMPKHGLDVGACEVFRFYKLVTLKGLIEPISMIVPRRSETYQEDIYPMTPGTEPALSADEWLSG-INRGPVLMSLKEGYNRPNKLVFKAPV----------------------------KEKKGGVVNGIDLLENVPP-----------RTENELLR---------------------------------------------------------------MFFRQQEELRRLKDELTQKD----------------------------------------------IKIRQLELELNNIRNSPNINNNNNNSNGSSI---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6Z546-1", "uniprot_id": "A0A8M6Z546_DANRE", "id": "A0A8M6Z546-1", "name": "Coronin", "aln": "-----MSWSSAYRSSKFRHVYGKAGSREQCYEGIPITHSVHDNQFCAVNPKFLAVVTESAGGGAFIVIPLHKPGRVDPHYPRVCGHQGSVMDIKWSPFMDNIIASSSEDCTVRIWQIPDNGLRRNLT---------EALMILIGHSRRVGLIEWHPTCSGILFSAGYDCKILMWNLEEGVAVKMIDSHPDVVLCMSFNTDGSLLATSCKDKKLRIIDPRSGKVLQESCCKS-LRVNRVVFLGNLRRVFTTGVSRWNSRQIALWDQDDLSCPLLE--EEIDGLAGALFPYYDPDTHMLYLAGKGDGNIRYYEVGAEKPFLQFLTEFRSAAPQKSLCVMPKRGVDVSECEIFRFYKLVTFRGLVEPVSMIVPRRSEAYQEDIFPMTAGAESALSAAEWLSG-IDRGPVLISLKEAYKRPNPVSLRASR----------------------------RDRR--MIKGIDLLENISM-----------NTDRELLT---------------------------------------------------------------TVYRQQEELRKLKEELREKE----------------------------------------------ERIQTLELELNNLRNTH------TH---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06440-1", "uniprot_id": "CORO_YEAST", "id": "Q06440-1", "name": "Coronin-like protein", "aln": "-----MSG-KFVRASKYRHVFGQAAKKELQYEKLKVTNNAWDSNLLKTNGKFIAVNWNASGGGAFAVIPIEEVGKAPDQVPLFRGHTAQVLDTDFDPFNDHRIASGSDDSKIGIWDIPENYKFHDHVDEDGEPIDIKPVKFLTGHARKVGHVLYHPVAENVLASSSGDYTVKLWNVETGKDMITLK-HPDMVTSMSFSYDGNYLATVARDKKLRVWNIREEKIVSEGPAHTGAKNQRVVWLGNSDRLATTGFSKLSDRQIGIWDAFNIEKGDLGGFYTVDQSSGILMPFYDEGNKILYLVGKGDGNIRYYEFQNDE--LFELSEFQSTEAQRGFAVAPKRMVNVKENEVLKGFKTVVDQ-RIEPVSFFVPRRSEEFQEDIYPDAPSNKPALTAEEWFSGKSVEGPILVSMRSIYDGSAPSFHEAKRPQQPTTQETALEEKKEQPKVEKPISESEKEVKQEAPKSPSPLKSASSSSTINHVLKEDNSINKLLKKSSDIDQVNNAEDPSRDTSGWEEADDEPAPIKIETPVTPTETKKDRTPKVEPSKELKPEPVSIATDRKQEQSLPQEEKSSEKTKSPEQEKSATPPSSITAAKTAITASSKEEPSAARTSPKSLGLKKSVEKLSTLVLQLEDVVDKLTKANLDKDERLLKLEQKIGELSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *:**:*:*:*:...:* :: : :*:.. *.:: .* :*:*: :::***:* ***: : *: : * . ** ..*:* .:.** *: *** *:* .: **:**:. :. . :.: * **:*:** : :**. ..:* *:. * .: :**:: * : :. *.*:: .***. :*. *:* .:*****: : *. :::.*. :. : :***:*** *: ***.*: . ***.:** ::. : :* :* *:*:** ..::***.***********. :: * * **:*. .*:.: * **: ::* *::: :* *. : :**:*::*****: :****:* :.. :.**:. **:.* ..*:*:*::. *. . .* :: : :. . *:. . .: .:** *:*:: ::: :* :: * *:*::: :. .. ", "identical_positions": 149, "similar_positions": 185, "identity": "22.54%" }, { "cls_id": "homologset.agr.MGI:2444286", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZG78-1", "uniprot_id": "D3ZG78_RAT", "id": "D3ZG78-1", "name": "", "aln": "MGNAPS----NSSEDE----------------------AAAAGGEGWSPHQDWAADSGATPG--------PGPAAAVLPSAAALLEPARLREAAAALRP--APPCESLVSRHHGALLRWLEERLGRGEESVTLEQFRELLEARGAGCSGEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHVIRQLQACSLVPGFIDIFSESKEGLGTHSSMILRFLHRNRVSSMVIPYPMLDHCNNMCTMRSSVLKDSLDQLLQKEK----ESPGDLARSPEMDKLKSVTKCYAYIETSSNPADIYRMTNGETSSYWQSDGSARSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRSASDLQEVRDVHIPSNVTGYVTLLENANISQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLHNTQKALQHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSIAKVMSSLCAISDHLDTQYDASSLISSMASVRQSLLLKYGKPLQLTLQACDVKGKEDKSGPENLLVEPWTRDGFLTETGKTRASTIFSAGTESAFQVTQIRIMVRRGGIGAQCGLVFAYNSPSDKFHAEEHFKRFEKYDRWKLQELRQFVKSRIGCSPDDLGEDDPIGWFELEEEWDEADVKLQQCRVAKFLMVKFLCTRQESAERLGVQGLSISGYLRP-ARAEAEQSILYAHCRRDTEN-IYGATLLLRTLQFIQQLAHDLVQQKESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECICAQTLLLQLLQSCFSVLQGDPQAVSEEEKPAAQRP-------EGIQAAKELYTHLCDVVDRADGESMPMEILKQEVRNTLLNGAAIFFPDRQTRRNQLFTMMKNVTEHERKQSLQLTFRSLCTYFSDKDPGGLLLLPEKSDLATMNTSEVLAVMNTLLSVAARECELLMLGRAHGEVGSVLFSLFWSVQGSLLSWCFLQLKSTDAAAKELAMDLIEKYVGQFLASMRVILESLLSQYSGKTIVEKLCNSVFSMAARQLVIFLLDFCTLDVSHCTLLREFSTLTELLKKLCSDPEGGLSKLDVETWQQ-EQPVVLHTWTKESTHNYENNCHEVSVFVSPGATYFEVEFDERCETEKRYDYLEFTDSRGGKTRYDTKVGTYKWPKKVTFKDGPRLQFLFHSDSSNNEWGYKFTVTAYGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVHQLGSNLAISQAKLTAVLNSPLWKPVFRHQICPELELEASWPTHPHQDGKEVKNIPDDPCRHFLLDFAQSEPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVHSGGKIALPEEFSQVYSLADGIRIWMLEMKQKSLVSMGNDSEEKRGLETAEVNPENLAKECIQKSLLLLKFLPMSKSSKENCDKLVPVDETDRLQPLDRRQRTS------------SVVEEHFQGSASPTEAATPAADDK----SPGLEMQPKLLPSSGPSAAEVS--TAEEPSSPSTPTRRPPFTRGRLRLLSFRSMEETRPVPTVKEKYPVLKDVMDFIKDQSLSHESIVKVLSLRKAQAQSILEVLRIIQYCTESLGQPHCFHPPYILFLLELLTCQKDFTNYFGHLEGCGADLHKEIRDTYYQLVLFLVKAIKGFSSINDRSLLPAVSCVQTALLHLLDMGWEPSDLAFFVDIQLPDLLMNMSQENISIHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCDDFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRFIQPYIHNYSWLLFAALALYSAHLTSTEHVDGEQLDPQARGSAATLRSQCMQLVGDCLMKAHQGKGLKALALLGVLPDGDSTSENQALPVTVSIQASEEQLEKKTAQPAEGPADAGLFVPCNGKRATDKEVGPLDCKQKKKAGEDLSIMKDPSCQIQVSDPPASDHVPPGLPDAEHP----------DRSSQAPMEEKAIT-PSPEQVFAECSQKRILGLLAAMLPPIKSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLQPAEVDAAVMKVLSAKHNLFATAD-NAVVPDGWKTTHLLFSLGAVCLDSRVGLDWACSMAEILRSLNNAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGG-----------GQECGTSQAQLSQYSQHFAFIASHLLQTSMDSHCPEAVEATWVLSLALKGLYKTLKTHGFEETHATFLHTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINTLTEHGDLELDERGDQEEELDRPVSS--PGEAEQKKLDPLESLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDSFFLEVQKRFDGDELTTDERIRSLAQRWQPSRSLRLEEQSAKAVDTDMIILPCLSRPARSDQATSESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSKRAVRDYLFRVNEATAVLYARHVLASLLAEWPGHVPVSEDILELSGPAHMTYILDMFMQLEEKHQWEKILQKVLQGCRESMLGTMALAACQFMEEPGMEVQVRESKHPYNNNTSFEDKVHIPGAIYLSIKFDPQCNTEEGCDELAMSSSSDFQQDRHNFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPHLPLGKIWEWLVGVACRQTGHQRLKAIHLLLRIVRCCSHSDLCDLGLLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALTELFFVTENRAQELGLLQEYLLALTTEDHLLRCAAQALQNIAAISLAINYPNKATRLWNVEC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SSH7-1", "uniprot_id": "ZZEF1_MOUSE", "id": "Q5SSH7-1", "name": "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "aln": "MGNAPS----NSSEDE----------------------AAAAGGEGWSPHQDWAADSGTTPG--------PGPAAAVLPSAAALLEPARLREAAAALRP--APPCESLVSRHHGALLRWLEERLGRGEESVTLEQFRELLEARGAGCSGEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHVIRQLQACSLVPGFIDIFSESKEGLGIHSSMILRFLHRNRISSMVIPYPMLDHCNNMCTMRSSVLKESLDQLVQKEK----ESPGDLARSPEMDKLKSVTKCYAYIETSSNPADIYRMTNGETSSYWQSDGSARSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRSASDLQEVRDVHIPSNVTGYVTLLENANISQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLHNTQKALQHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSIAKVMSSLCTITDHLDTQYDASSLISSMASVRQNLLLKYGKPLQLTLQACDVKGKEDKSGPENLLVEPWTRDGFLTETGKTRASTIFSTGSDSAFQVTQIRIMVRRGGIGAQCGLVFAYNSPSNKFHAEEHFKRFEKYDKWKLQELRQFVKSRIGCSSDDLGEDDPIGWFELEEEWDEADVKLQQCRVAKFLMVKFLCTRQESAERLGVQGLSISGYLRP-ARAEAEQSILYAHCRRDTEN-IHGATLLLRTLQFIQQLSHDLMQQKESGLKHKSFLDFAGLDLQIFWKFYSKLKQNRREECICAQTLLLKLLQSCFSVLQGDPQAASEEEKPTAQRS-------EGIQAAKELYTHLCNVVDKPNGNSMPMEILKQEVRNTLLNGAAIFFPDRQTRRSQLFTMMKSVTEHERKQSLQLTFHSLCTYFSDKDPGGLLLLPEKSDLATMNTSEVLAVMNTLLSVAARECELLMLNRSHGAVGSVLFSLFWSVQGSLLSWCFLQLKSTDAAAKELAMDLIEKYVGQFLASMRVILESLLSQYSGKTIVEKLCNSVFSMAARQLVIFLLDFCTLDVSHCTLLREFSTLTELLKKLCSDPEGGLSKLDVETWQQ-EQPVVLHTWTKESTHNYENNCHEVSVFISPGATYFEVEFDERCETEKRYDYLEFTDSRGGKTRYDTKVGTYKWPKKVTFKDGPRLQFLFHSDSSNNEWGYKFTVTAYGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVHQLGSNMAVSQAKLTSVLNSPLWKPVFRHQICPELELEASWPTHPHKDGKEVKNIPDDPCRHFLLDFAQSEPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVNSGGKIALTEEFSQVYSLADGIRIWMLEMKQKSLLSLGNDSEEKRGLEAAEVNPESLAKECIQKSLLLLKFLPMSKSSKENCDKLETVDETDHLQPLDRRQRTS------------SVVEEHFQGSASPTEAATPAAGDR----SPALEIQPKLLPSSGPCVAEVS--TAEEPSPPSTPTRRPPFTRGRLRLLSFRSMEETRPVPTVKEKYPVLKDVMDFIKDQSLSHESVVKVLSLRKAQGQSILEVLRIIQYCTESLGQPHCFHPPYILFLLELLTCQKDFTNYFGHLEGCGADLHREIRDTYYQLVLFLVKAIKRFSSINDRSLLPALSCVQTALLHLLDMGWEPSDLAFFVDIQLPDLLMNMSQENISVHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCDDFDLCYGCYTAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSWLLFAALALYSAHLTSTEQVDGEQLDPQARTNAATLRSQCMQLVGDCLMKAHQGKGLKALALLGVLPDGDSTSENQALPVTVSFQASEEQ------------ADAGLLVPCNGKRAADTEVRPLDYKQKKKAGEDLSIVKDPSCQTQVSDAPASAHVPPGLPDAEHP----------EVSAQVLVEEKAIT-PNPEQVFAECSQKRILGLLAAMLPPIKSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLQPAEVDAAVMKVLSAKHNL------------------------------RVGLDWACSMAEILRSLNNAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGG-----------GQECGTSQSQLSQYSQHFAFIASHLLQTSMDSHCPEAVEATWVLSLALKGLYKTLKAHGFEETHATFLQTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINTLAEHGDLELDERGDQEEELDRPVSS--PGEAEQKKLDPLENLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDSFFLEVQKRFDGDELTTDERIRSLAQRWQPSRSLRLEEQSAKAVDTDMIILPCLSRPARSDQATPESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSKRAIRDYLFRVNEATSVLYARHVLASLLAEWPGHVPVSEDILELSGPAHMTYILDMFMQLEEKHQWEKILQKVLQGCRENMLGTMALAACQFMEEPGMEVQVRESKHSYNNNTSFEDKVHIPGAIYLSIKFDPQRNTEEGCDELAMSSSSDFQQDRHNFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPHLALGKIWEWLVGVACRQTGHQRLKAIHLLLRIVQCCSHSDLCDLGLLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALTELFFVTENRAQELGLLQEYLLALTTEDHLLRCAAQALQNIAAISLAINYPNKATRLWNVEC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43149-1", "uniprot_id": "ZZEF1_HUMAN", "id": "O43149-1", "name": "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "aln": "MGNAPS----HSSEDE----------------------AAAAGGEGWGPHQDWAAVSGTTPG--------PGVAAPALPPAAALLEPARLREAAAALLP--TPPCESLVSRHRGALFRWLEERLGRGEESVTLEQFRELLEARGAGCSSEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHIIRQLQACSLVPGFTDIFSESKEGLDIHSSMILRFLHRNRLSSAVMPYPMLEHCNNMCTMRSSVLKESLDQLVQKEK----ESPGDLTRSPEMDKLKSVAKCYAYIETSSNSADIDKMTNGETSSYWQSDGSACSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRNASDLQEVRDVHIPSNVTGYVTLLENANVSQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLHNTQKALRHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSVAKVMSSLCTITDHLDTQYDASSLILSMASVRQNLLLKYGKPLQLTLQACDVKGKEDKSGPENLLVEPWTRDGFLTETGKTRASTIFSTGTESAFQVTQIRIMVRRGGIGAQCGLVFAYNSSSDKFCAEEHFKRFEKYDKWKLQELRQFVKSRIGCSSDDLGEDDPIGWFELEEEWDEADVKLQQCRVAKYLMVKFLCTRQESAERLGVQGLTISGYLRP-ARAEAEQSVTCAHCRKDTEESVCGATLLLRTLQFIQQLAHDLVQQKESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECVSAQTLLLQLLQSCFSVLQGDVLAASEEEKAPIQSP-------KGVEAAKELYTHLCDVVDKVDGDSVPMEILKQEVRNTLLNGAAIFFPNRQTRRNHLFTMMN-VTEQEHKQSLQLTFRSLCTYFSDKDPGGLLLLPEKNDLAKMNISEVLAVMDTLVSVAARECELLMLSGAPGEVGSVLFSLFWSVQGSLLSWCYLQLKSTDSGAKDLAVDLIEKYVGQFLASMRAILESLFSQYSGKTIVERLCNSVFSMAARQLVIFLLDFCTLDIPHCVLLREFSVLTELLKKLCSGPEGGLRKLDVETWQQ-EQPVVLHTWTKESAHNYENNCHEVSVFVSPGATYFEVEFDDRCETEKRYDYLEFTDARGRKTRYDTKVGTDKWPKKVTFKAGPRLQFLFHSDSSHNEWGYKFTVTACGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVRQLGSNMVVPQAKMALVLSSPLWKPVFRHQVCPELELEASWPTHPHRNSKEVKNIPDDPCRHFLLDFAQSEPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVNSGGKIALSEEFAQVYSLADGIRIWMLEMKQKSLMSLGNEAEEKHSSEATEVNPESLAKECIEKSLLLLKFLPTGISSKESCEKLETADETSHLQPLNKRQRTS------------SVVEEHFQASVSPTEAAPPATGDQ----SPGLGTQPKLPSSSGLPAADVSPATAEEPLSPSTPTRRPPFTRGRLRLLSFRSMEEARLVPTVKEKYPVLKDVMDFIKDQSLSHRSVVKVLSLRKAQAQSILEVLKITQHCAESLGQPHCFHPPFILFLLELLTCQKDFTNYFGHLEGCGADLHKEIRDTYYQLVLFLVKAVKGFSSLNDRSLLPALSCVQTALLHLLDMGWEPNDLAFFVDIQLPDLLMKMSQENISVHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCDDFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSWLLFAALALYSAHLASAEDVDGEKLDPQTRSSATTLRSQCMQLVGDCLMKAHQGKGLKALALLGVLPDGDSSLEDQALPVTVPTGASEEQLEKK------AVQGAELSEAGNGKRAVHEEIRPVDFKQRNKADKGVSLSKDPSCQTQISDSPADASPPTGLPDAEDS----------EVSSQKPIEEKAVT-PSPEQVFAECSQKRILGLLAAMLPPLKSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLLPAEVDAAVIKVLSAKHNLFAAGD-SSIVPDGWKTTHLLFSLGAVCLDSRVGLDWACSMAEILRSLNSAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGG-----------GQECGDSRAQLSQYSQHFAFIASHLLQSSMDSHCPEAVEATWVLSLALKGLYKTLKAHGFEEIRATFLQTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINALAEHGDLELDERGDREEEVERPVSS--PGDPEQKKLDPLEGLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDYFFLEVQKRFDGDELTTDERIRSLAQRWQPSKSLRLEEQSAKAVDTDMIILPCLSRPARCDQATAESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSKRAVRDYLFRVNEATAVLYARHVLASLLAEWPSHVPVSEDILELSGPAHMTYILDMFMQLEEKHEWEKILQKVLQGCREDMLGTMALAACQFMEEPGMEVQVRESKHPYNNNTNFEDKVHIPGAIYLSIKFDSQCNTEEGCDELAMSSSSDFQQDRHSFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPHLPLAKIWEWLVGVACRQTGHQRLKAIHLLLRIVRCCGHSDLCDLALLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALTELFFVTENRAQELGVLQDYLLALTTDDHLLRCAAQALQNIAAISLAINYPNKATRLWNVEC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P8V5-1", "uniprot_id": "A0A8M9P8V5_DANRE", "id": "A0A8M9P8V5-1", "name": "", "aln": "MGNAESGCGAGSGDEEDVETESPVFAEGSPASAATGTRAGSGGGGGGGGAGGAAAAGSAGPGRSGRGSANPPAPSHGLPTPEALLEQVKLREAAARMSDSWVAISESVLARNESALVRWLEERLSRGEESVTLEQFCEMLESRDAAR--DECEEAFGQFDAEGDGIVDVENMLMALRNSNGANLQGELSHVIRQLQACSLTPGFVDIFSKSKDRLKAHASKILKFLHRNRIPSNVIPFPVLDGYNSICTMRTSVVQDFLDYLLQKEKDLDIQYRAELNHDPDVDKVKVVTQCFSFIEASSNNTDVNKLTNGETVSFWQSDGSARSHWIRLKMKPDIVLRRLAIAVASNDHSYMPQLVSIAVGKNRRSLQEIRDVRIPSNITGYVPLLENANISHPYIQINIKRCLSDGCDTRIHGLKTMGYQITKSKEVSVSDASAIWYLSLLTSLVTASMETNPVLAQTVLQSTQKALQHMPPLSLTPSSTEFPKFFSANILEEVDGFLLRIANCCVSPEAELTLLAFALARGSVAKVLISLSGICGHLDSEYRASSLLASMSSVRLRLLHRNGKPLQLHLMACDVKSKEEKSGPENMLTEPNTGDGFLTENGKRKASVILSTENQSCFQVTQIKIKVRKGAIGAKCGLVFAYN-DCEVFDADKHFKRFKKYDSWDYKDYKEFVQDSTRITES--SEEEPIGWFEVEEDWNDVDIKLQQCRVSKFLMVKFLCARQDTAERLGVQQLIFSGYLCPDSERMEDVEDLSAQAEGSDSGLVTGLALMKKTLYFIQQLTRDMDVSLS---KQKTLLDFSDLNLLLFWDFYRKLRSIEGEEAIKTRVLLLQLLQNCFPMLPSPTESQPSDLSASASASPSGSSDVDPAEAVGELCRHLCQVVDGPEGETAAEKALRKEAVKAILNGAAIFYPDKQSRRDKLFHMMKNITEENQPESVKLTFESLCSYFSDQDPKGLLMLPPKGAPSDFDISPVLSVMDTLLIVASRECEVLMSESSGGSIWRVLLSLFWALQGSLLSWCFLQLKGGTATSSDLAREILLKYVEQFLSGTRDILIPLTKSFSGADIMKKLSGSILAMATRQLTIFLLELCALDIPHCVLLKRFYPISDLLKNMSSDTDDIFSKVDLEGCQQPQQPVVLRTWQMESPHNYENSRHETTVFVCPGATSFEVEFDARCETEKRYDYLEFTDARGGKVRYDMKVGTEKWPKKVTFKAGPQLQFLFHSDSSNNEWGYKFTVTAYGLPDVTVSWTSDLQLLVSRLMGRLASRTMALKSPYEIRGVKELPATLMNHILSCPLWKPVFRHGLS-GLPGEQKLALASPEASQEDPAPLGDELVEFLKEFARWDPSQDSSDGRTELMRTLLVNCKKQLIRNEIASGLKVDQAVNAIWAAMVYHTPALHPCLKSFVAKNGQSGLSEDLVQVYTLADGIRTWMLEMKQRYLMGKMNGVEEK-DEGQNEVTMESLAEVCISRSLFLFQFSPSGGTSAPQDQETSRPEDIACAAPLLRSISTSEGDFQPSPSLSISQTPHGAEAVTSPVSASRERTQDQSFSASGDAGASGSISSQGATGSSESLQSQTGEPLSPSVFPRKAPFSRGRLRLLSLRSMEEPRMAPPVKERFPILKHILSFMKDMVINESSVLQTLALKKAQAVSVCEVLELVQQCILTLGKPHLFQAPCILFLQELLACQKDFTNYFSQLVGSGQEMRERVRHSYHQLVLMLVEAVQGFSALNEKVLLPALSCVQTCLLHLLDMSWEAEDLSLFLDIKLPDLLLAMSQENISVHDIAISQWTEEDEIADYERNCEWMDECLDGMFEKWFDKISQASVEDKRKMHMFIARYCDLLNVEISCDGCERIAPWHRYRCLQCTDMDLCKTCFLSGAKPEGHEDDHEMVNMEYACDHCQGLIVGSRINCNVCEDFDLCFGCYNAKKYPDSHLPTHRITVYPMVTIRISDRHRLIQPYIHNYSWLLFAALALFTSELISEKAQDGESLDDVTLGNASALQTQCFDIIKECLLKGQTGKGLRASALLSLLSSNESATVSELCPATAGSSQDISSTDTS-------SLPSSTTAICSPPLPRDRGGGEGDEKRRRKLVSQDTS--DSSCASQTPSVSSEDTLSPGVRGSESSGDTITSPTSENLDAYKEQEEKTARGPLQEHVFAECSRERILGLLAAMLPATKPGSPLSLSSLSPILPLLFRVVISNAGCLNETYHLTLGLLGQLLLRICPAEADAAVTEALTDKFELLNLGDGAALDVAGWKTTQLLFSLGAVCLDSRIGLDWACSVADILRNLNVSSQWCTVLASFTDHCILQLPQHLKRTNLFTLLVLVGFPEVLCMGTQAVFIDNANEQHNMILLKHFTEKNRAAVVDVKTRKRRTVKDYQLVQAHESSSRNDSESHEGQAVSPNSAHLSHYLKNFTSIVSFLLQTGVESSAQDAVEATWVLSLALKGLYNTLKKHGVDQAQEALQGSGLMQLLVRKCSKGTGFSKMWLLRDLEILSIMLYSSKREIHSMAEDADTETDGEKEREKEQDSDHSSCCADDADPNRPDPLEGLDEETKICFQITHDALNAPLHILRAMYELQMKRTDSFFLEVQKRFDGDAIKTDETIRTLAQKWQPSKRPRSDERSTKAVDTDIIIVPCVSKPTRCERATEETNVVTQKLITNTESDLQLSYAKQRRTKSSALLHKELDARSNKAVRQYLFKVNEAIAILYARHVLATLLADWPSDTPIREEDLELSGASHMAYILDMLMQLEERPMWEKILQKVLRGCSQSMLGNLSLTACQFMEEPGMAVQVRESKHPYDNNTNFEDKVHIPGAIFLSVKFDSRCHTEEGCDELLMASSSDFLQDLHTFSGSHQKWTDFEIPGDTLYFRFISDMSNTEWGYKFTVTGGHRGRFQTGFEILKQMLADEQALTHLPLPDIWEWQVGVACRQTGNQRLKAVHLLLRLLQCPSQ-WACDLTLLRPLWQLFTTMESGLCQDPTSITVLLPLHRALTELFFIAEAKAMEQNVLQEYLLALTTNEQLVVRTAQALKNIAAISLAINYPNKSTKQLNLSP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** * *.::* *.:.** * . . ** ..: ** * .: **.. **** .:****** : .. .**:::*:..**.*******.*********** *:**:*.*. :: ****.******** **.**** **:**.**********:*********.*** ****:**: * *:* **:******:.* *:*:*:*: *.:****:**::: ** *:**** : .:* :.*::**:* *::*:::**:*** :*: ::***** *:******* ***********:***:*:****:.*:***** *::***:. .***:***:****:****.******:*: *:*******************:::*:* .*.. *********** ***************.:.****:.*****:*******:*.**:*..*:*.*:*****.**:**:.** :**.*************:***: **. * .***::* ****: **:*** ** : ****** * *****.**:******:*.** * ******.** :**.*:*: .:*.******:* **:*.***:******** .: * *::*****:*** *. :: ::**:. : . .*::******:**:*::.*:*******:*:*******:**::******* * :**** * :. : . *:.. . . : * :*: :** *****::*: . . * *::***:.*:* :**.** **:. **.: ::.***:***.**.:* . : ..: ... . . . :*. ** ***:*** :*:: . : *::*. :::*******:*::*:**.:** **: :**.:: :*::***.***:****:** ***:** *. : :: * **:**:**: **:****:** : * : **:****::********:****. : :.:** ::: *** ***:. * ** .* ..:** *:::*..*:::**:***.****::*:**:.**.**:.* :::***::.*..:. : *:*:* ** :*****:** **.*****. **.:**:.**** ****** ***************:** *.*** **** ********* **:**********:*********** *****:*** ***************: ***** :: . :. : : :*..********* :. * * . . . . .:* .* .** :**: :*:*: .. :**:: :: *:** :.:*.:* .:****** :**:**:** *: *:.:* ..*: .*.*:: ***:****** *******: *:. * *** . **. *.**: **.:**:*::* * . :* . :: :: ** : ** * . . :. .**..*: : *: * . .: .... :: : ** .**. .*:.**:********:*****.* .*.***::*:**.::.*:** :.. *:::.*:*:***. *: ***.: * * :**:** *:.* **** ***:*********.:* *.* :::..:*.:*:****:**:*:: **::*:: ****:*****.*******.**..**::*:**:*****: *******:** .****:****:** ::*.****** ***** *::**:* . *.:****************:******:.************:**********.*.***** *********::********:* *:*****:*****:*** ****. .***** **.:**********:*:******************:::.* * : ***.** : .*::*::**:::: :**:*.: ****:* ***.:*...:*: .: *.*. . .. : . . . * *::.* . : *.** * .. .:. ..*: .:* . : .: ***: * *:******::***********. *.*..:.* .*. :***:*:******* ***************::*: ***.**** :.*: *.:* *:*******:*:***.** :. * *:*:****** *** :**:**:**********:***:**:.*::***** **:*:**********.:********:********* ** . . ::**:* ::*: *.*.***:.::* . :****************:*** **.:: : :: :.*::***:********** *****************:**::::*..* * * . ::*:* : ** ..:.: :: ****.*** *:*** ::*************:******:** ************ :.*** **:***:****: * :*:*:******:**:**:*:*:*.::** *:* ******:.***:** *******:**:*******:.:*::*:*:***:**** ::********:***:**...*: *: *****.:**:*****:*****: *********:** :.***.::*:********** ********.*:***.***********:**:***.: :******** *:***** ** *.****:***.***:******:** **********:****.** **************::*:.:.**.* .**** *********:*****:*****:::* .: *** **:******* ** ** :* *. :*************::* :* * .:**:*******:::*: :****:**************:*: *:. ", "identical_positions": 1679, "similar_positions": 781, "identity": "54.91%" }, { "cls_id": "homologset.agr.MGI:2444287", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9Q998-1", "uniprot_id": "A0A8M9Q998_DANRE", "id": "A0A8M9Q998-1", "name": "Phospholipid-transporting ATPase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFFGLDCA------------RKKEKEVERKIRANDREYN--SSFKYATNCIKTSKYNPFSFLPLNLFEQFQRIANAYFLFLLILQVIPAISSLSWFTTVVPLVLVLSVTAAKDAIDDINRHRSDRQVNNRKVNVLI-------------------------------------------------------------------------------------------------------------------SGKLTSEKWMNVQVGDIIKLENNQFVTADLLLLSSSEPLNLVYIETAELDGETNLKVKQSLTVTGDMGHNLEALAAFNGEVCCEPPNNRLDRFTGTLTFDTQ------KYSLDNERVLLRGCTLRNTDWCFGLVLFAGPETKLMQNCGKSTFKRTSIDRLMNVLVLFIFALLALMCIILAVGHGIWENYTGSKFNVFLP---HEENAAFSA------FLTFWSYIIILNTVVPISLYVSMEVIRLGNSYYINWDRNMYHTRTDTPAEARTTTLNEELGQIKYIFSDKTGTLTQNIMTFNKCSINGKSYGDVFQHYSGQTLEITEET--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPVDFSFNGLADPKFLFYDHSLVEAVK-----LELPEVHAFFRLLALCHTCMAEEKKEG--------------------HLVYQAQSPDEGALVTAARNFGFVFRSRSPETITIEEMGIQRTYELLAILDFNNVRKRMSVIVRNP------EGKLSLYCKGADTIIYERLHP----SCSKLMEVTTEHLNEFAGEGLRTLVLAYKDLDEDYFAEWKQRHHESSVAMEDREEKLDKVYEEIEKDMMLIGATAIEDKLQDGVALTIELLAKAEIKIWVLTGDKQETAENIGYSCNLLREEMNDVFIVA-AHSPEEVRQELRDARL-----------------KMQPSTEQDKFLIPE----VILGNT--PKVVQ------------DEH----------------------------------VNGEYGLVINGHSLAFALES-SMELEFLRTACMCKTVICCRVTPLQKAQVVELVKRYKKAVTLAIGDGANDVSMIKAAHIGVGISGQEGMQAVLSSDFSFAQFRFLQRLLLVHGRWSYLRMCKFLRYFFYKNFTFTFVHFWYAFFCGFSAQTVYDEGFITLYNLVYTALPVLGMSLFDQDVNANWSLEFPQLYVPGQLSQYFSKRAFMMCALHSCYSSLVLFFVPYATTYD--TARADGRDGADYQSFALITQTCLTVTVCVQLGLDLSYWTVVNHLFVWGSLGMFFFLTFTMYTDGLFKLRPASFAFIGTARNCLNQPNVWLTVALTALLCVLPVVAYRFIYCQIYPTINDKVRYKMRQMKEPAPRP-----RPR---LTRR--STRRSGYAFSHAQGYGDLVTSRRFLRRPAPARSAGFTPAGRSPGFKPTGRSAGYSPVGREQNPKQKVEPTS------LQMFRAVKDASF-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2LAJ5-1", "uniprot_id": "A0A0G2LAJ5_DANRE", "id": "A0A0G2LAJ5-1", "name": "Phospholipid-transporting ATPase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSLLSACGINVK------------KKK-VEEERRLRANDREFN--LSFKYANNAIKTSKYNVFTFLPLNLFEQFQRLANAYFVFLLILQLIPQISSLSWFTTVVPLLLVLSITLAKDLSDDITRHKNDKQVNNRKVEVLI-------------------------------------------------------------------------------------------------------------------DGELKTERWMNVQVGDIVKLENNEFVTADLLLLSSSEPLNLIYIETAELDGETNLKVKQALTLTGELCNDIQRLAAFKGEVRCEPPNNRLDKFTGTLVVGGE------TFALDNERILLRGCTLRNTEWCFGLVLFGGPDTKLMQNSGKSIFKRTSIDHLMNVLVLFIFGFLAFMCTILSIGNAIWEYQEGNSFIVFLPRA-DGANASLSA------FLTFWSYVIILNTVVPISLYVSVEILRLGNSYFIDWDRKMYHVKSDTPAQARTTTLNEELGQIKYIFSDKTGTLTQNIMTFNRCSINGKSYGEVVD-FAGQRVEVTEKT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKVDFSWNLLADPKFFFHDHKLVEAVK-----LGSPEVHAFFRLLALCHTVMPEEKTQG--------------------DLFYQAQSPDEGALVTAARNFGFVFRARTPETISVVEMGIETTYELLAVLDFNNVRKRMSVIVRNP------EGKLMLYCKGADTIIYERLHP----SCSKVMEVTTEHLNEYAGEGLRTLALAYKDLDEDKFAEWRRRHHEASIALEDREEKLDAIYEEIEKDLILIGASAVEDKLQDGVPQTIEQLAKADIKIWVLTGDKQETAENIGYSCNMLREEMTEIFIVA-ANTAEEVREELVNARK-----------------KMSPESGDEPPMEKS----RFLGKK--SQVVE------------DEK----------------------------------VDGEYGLVINGHSLAFALQK-DMQVELLRTACMCQTVICCRVTPLQKAQVVELVKKHKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGMQAVLSSDFSFAQFRYLQRLLLVHGRWSYLRMCTFLRYFFYKNFTFTFVHFWYAFFCGFSAQTVYDEWYITLYNLVYTALPVLGISLFDQDVNDRWSFQYPQLYAPGQMNQYFSKMAFAKILLHSCYSSLILFFVPWAAMWD--TVRDDGKDIADYQSFALLAQTCLLIAVSVQLGLDTYYWTAVNHFFLWGSLSVYFAVTFTMYSNGMYLIFTSSFPFIGTARNSLNQPNVWLTIFLTTILCVLPVVAKRFLFIQFKPTINDKVRHKVKQAKAEPPPP-----PQR---FPRRRISTRRSGYAFSHARGYGDLVTSGRFLRIPVKSRPALFSKNE--------------SPVADS------TPQTY------ISIFEETQNP-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A3FIN4-1", "uniprot_id": "AT8B5_MOUSE", "id": "A3FIN4-1", "name": "Phospholipid-transporting ATPase FetA", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKYVKAFVSEISWDCSWYCSAMQERRNEDRQKEEEERILQANNRRFN--SLFEYPDNSIKTSKYGFFNFLPMNLFEQFQRLANAYFLILLFLQLVPQISSLAWYTTVIPLIVVLSITGVKDAIDDVKRHRSDQQINNRSVSILV-------------------------------------------------------------------------------------------------------------------NGRVEEIKWRNVQVGDIIKLENNHPVTADMLLLSSSEPYGLTYIETADLDGETNLKVKQAISVTSAMEDNLELLSSFNGEVRCDPPNNKLDKFSGTLSYLGN------TYLLNHERLLLRGCVIRNTDWCYGLVVYTGQDTKLMQNSGRSTFKRTHIDHLMNVLVVWIFMFLGGMCFLLSIGHGIWENSRGYYFQAFLPWKHYITSSATSS------ALIFWSYFIVLNTMVPISLYVSVEIIRLGNSYYINWDRKMFYAPKNMPAQARTTTLNEELGQVQYVFSDKTGTLTENVMIFNKCSINGKTYGYSYD-DNGEYVPKSPK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DKVDFSYNHLADPKFSFYDKTLVEAVK-----SEDPLVYLFFLCLSLCHTVMSEEKVEG--------------------ELVYQAQSPDEGALVTATRNFGFVFCSRTPETITVIEMGKIRVYRLLAILDFSNERKRMSVIVRTP------EDRVMLFCKGADTIIYELLHP----SCASLSEVTMDHLDDFASEGLRTLMVAYRELDKAYFQTWIKKHGEAWLTLENRERKLALVYEEIERDLMLLGATAIEDKLQRGVPETIVTLSKAKIKIWVLTGDKQETAVNIAYSCRIFKDEMDGVFMVE-GTDRETVLEELRTARK-----------------KMKPESLLESDPINM----YLARKPKMPFKSL------------DEV----------------------------------ANGNYGLVISGYSLAYALEG-SLEFELLRTACMCKGVVCCRMTPLQKAQVVDLVKRYKKVVTLAIGDGANDISMIKAAHIGVGISNQEGMQATLSSDFSFCQFHFLQRLLLVHGRLSYNRMCKFLSYFFYKNFAFTLVHFWYAFFNGFSAQTVYDIWFITFYNLIYTSLPVLGLSLFEKDVNETWSLCYPELYEPGQHNLYFNKKEFVKCLLHGIYNSFVLFFVPMGTVFN--SERNDGKDISDFQSFSLLVQTTLIGVMTMQIALRTTSWTMINHTFTWGSLGLYFCILILLCSDGLCLRYPSIFNFLGVARNSLSQPQIWLCLILSTILCMIPLIGYNFLRPLLWPINADKVLNRIHFCLKHPIPT-----QVQ---TKIKHPSLRRSAYAFSHKQGFGALITSGKTLKSSALAKSKRFL---------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R7E2-1", "uniprot_id": "M0R7E2_RAT", "id": "M0R7E2-1", "name": "Phospholipid-transporting ATPase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKYVKAFISEILWDCSWFCSAMYERENEQRQNEEEERILQANNRRFN--SLFEYPDNSIKTSKYSFFNFLPVNLFEQFQRLANAYFLILLFLQLIPQISSLAWYTTVIPLIVVLSITGVKDAIDDVKRHQSDQQVNNRSVLILV-------------------------------------------------------------------------------------------------------------------NGRIEENKWRNVQVGDIIKLENDHPVTADVLLLSSSEPYGLTYIETADLDGETNLKVKQAVSATSDMEDNLELLSAFNGEVRCEPPNNKLDRFSGTLSYLGD------TYFLDYERLLLRGCIIRNTDWCYGLVVYTGPDTKLMQNSGRSTFKRTHIDHLMNVLVLWIFMLLGGMCFLLSIGHGIWESNRGYHFQAFLPWERYITSSAASS------ALAFWSYFIVLNTMVPISLYVSVEIIRLGNSYYINWDRKMFYAPKNTPAQARTTTLNEELGQVEYVFSDKTGTLTENVMIFNKCSINGKTYGYSYD-ENGQCVPKSPS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NKVDFSYNHLADPKFSFYDKTLVEAVK-----SEDPLVYLFFLCLSLCHTVMSEEKVEEVRRGHQSPGTVLLPFSLLSGELVYQAQSPDEGALVTASRNFGFVFHSRTPETITVIEMGRVRVYRLLAILDFSNERKRMSVIVQTP------EDRVMLFCKGADTIIYELLHP----SCAALSDVTMDQLDDFASEGLRTLMVAYRELDKAFFQTWIKKHGEAWLTLENREKKLALVYEEIERDLVLLGATAIEDKLQSGVPETIVTLNKAKIKIWVLTGDKQETAVNIAYSCRIFKDEMDAVFMVE-GTDRETVLEELRTARK-----------------KMKPESLLESDPINI----YLARKSKMPFKAV------------DEV----------------------------------PNGSYGLVISGCSLAYALES-NTEFELLRTACMCKGVVCCRMTPLQKAQVVDLVKRYKKVVTLAIGDGANDIGMIKAAHIGVGISGQEGMQATLSSDFSFCQFRYLQRLLLVHGRWSYNRMCKFLSYFFYKNFAFTLVHFWYAFFNGFSAQTVYDIWFITFYNLIYTSLPILGLSLFEKDVNETWSLCYPELYEPGQHNLYFNKKEFIKCLLHGIYSSFVLFFVPMGTVFN--SERSDGKDISDFQSFSLLVQTTLIWVMTMQIALSTTYWTMINHAFTWGSLGLYFCILFLLCSDGLCLMFPSVFNFLGVARNGLNQPQMWLCLVLSSVLCLIPLMGYNFLKPILWPINVDKVLNRIHFCLKHPLPP-----PVQ---IKVKHPGLRRSAYAFSHKQGFGALITSGKTLKSRAFTRR-------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VGD4-1", "uniprot_id": "Q9VGD4_DROME", "id": "Q9VGD4-1", "name": "Phospholipid-transporting ATPase", "aln": "--------------------MIGGRRCSEAARRLRRRPDTLELSVLGGQPIETELQEDNERTPTKGAGNVDEPGIEAPEASCSAPSKRTRWFQFARSSKNRRKRLHCNEDEDVKQPERRNSDLEGSPRACLAQPEGMNIGSSTQTIATPLMIGDSFYSLAPGGGNPPPNKSDDQELYKQRDPSVTSESKSVPSLRRLSQIRRRRSSYYFSENERRIRANDKEFN--AQFKYHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAISSLTPVTTAIPLIGVLTLTAVKDAYDDIQRHISDSQVNNRKSKTLR-------------------------------------------------------------------------------------------------------------------NGKLVEAKWSEVQVGDVIRLDNNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFNGEIICERPNNLLNKFDGTLIWRGQ------RFALDNEKILLRGCVLRNTQWCYGVVVFAGVDTKLMQNSGKTQFKSTGVDRLLNFIIIGIVLFLVSICALFAIGCAIWEGLIGQHFQLYLPWEHIIPKDYIPTGATVIGLLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTLNEELGQIQYIFSDKTGTLTQNIMTFNKCSINGRSYGDVIDLRTGELVEITEQQTIFQNSNTNNRPSPLSGAIVAPPAAPPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMDASEKRPGLKHVRYSAPSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVKILHDSQQTETHNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTSTLSTTKHHHHRSKAFATNWSSSPHRVHALQSVDFSANPHHESDFRWYDRTLLDAVR-----SDEEHSHVFFRLLALCHTVMAET-VDG--------------------KLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITIEVMGQTEEYELLNILDFNNVRKRMSVILRR-------GDSMVLYCKGADNVIYDRLHG----GQEDLKARTQDHLNKFAGEGLRTLALAERRLTEQYYNDWRSRQQEAALSMDSREQKLNAIYEEIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIKIWVLTGDKQETAINIGYSCQLLTDELADVFIVD-GNSVEEVEKQLRQFKESIKIYNRFRPGGFDPFDRLNSDSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKDNKGGPDSAECNNLFGDEKGSEDGGTASIVVDENTGFALVVNGHSLVHCLSP-ELENKFLDIASQCKAVICCRVTPLQKALVVELIKRAKNAVTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVHGRWSYYRMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFEQDVSDKNSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPYGVYKD--GVSANGFVVSDHMTLGAVVATILIVDNTAQISLYTSYWTVVNHVTIWGSLVWYFVLDYFYN-------YVIGGPYVGSLTQAMKDLTFWVTMLITVMALVAPVLAYKFYLLDVHPSLSDKIRQKSLKKIHSRASS-----DVRRTASSRRGRRSVRSGYAFAHQEGFGRLITSGKIMHKLPQDFAFPLGLGTKKTQVLHNNLNSADGPNSKGNNVTGHHMVNN------NTNMRHNQNQNHSSMADITADGRGNGGDDGRGSGGSDDMSPRAPCQDLDTINL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12675-1", "uniprot_id": "ATC4_YEAST", "id": "Q12675-1", "name": "Phospholipid-transporting ATPase DNF2", "aln": "MSSPSKPTSPFVDDIEHESGSASNGLSSMSPFDDSFQFEKPSSAHGNIEVAKTGGSVLKRQSKPMKDISTPDLSKVTFDGIDDYSNDNDINDDDELNGKKTEIHEHENEVDDDLHSFQATPMPNTGG--FEDVELDNNEGSNNDSQADHKLKRVRFGTRRNKSGRIDINRSKTLKWAKKNFHNAIDEFSTKEDSLENSALQNRSDELRTVYYNLPLPEDMLDEDGLPLAVYPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHILSGVKNENVAVDNVSLWRRFKKANTRALIKIFEYFSENLTAAGREKKLQKKREELRRKRNSRSFGPRGSLDSIGSYRMSADFGRPSLDYENLNQTMSQANRYNDGENLVDRTLQPNPECRFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRD-ITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNIRNEPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYKQKP-RSRDYFEFGTIGGSASTNG------FVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVLLYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRKRQGVDVESEGRREK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEIAKDRETMIDELRSMSDNTQFCPEDLTFVSKEIVEDLKGSSGDHQQKCCEHFLLALALCHSVLVEPNKDDPK------------------KLDIKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQGVQKEFQVLNVLEFNSSRKRMSCIIKIPGSTPKDEPKALLICKGADSVIYSRLDR--TQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVN-----------------NLVTKYLREKFGMSGSEEELKEAKREHGLP----------------------------------------------------QGNFAVIIDGDALKVALNGEEMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICLSLAVFYGWTGIWTS------SSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPRFTIDCIRKIFYPKDIEIVREMWLRGDFDLYPQGYDPTDPSRPRINEIRPLTD-FKEPISLDTHFDGVSHSQETIVTEEIPMSILNGEQGSRKGYRVSTTLER--RDQLSPVTTTNNLPRRSMASARGNKLRTSLDRTREEMLANHQLDTRYSVERARASLDLPGINHAETLLSQRSRDR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32660-1", "uniprot_id": "ATC5_YEAST", "id": "P32660-1", "name": "Phospholipid-transporting ATPase DNF1", "aln": "MSG----------------TFHGDGHAPMSPFEDTFQFEDNSSNE-DTHIAPT----------HFDDGATSNKYSRPQVSFNDETPKNKREDAEEFT--------FNDDTEYDNHSFQPTPKLNNGSGTFDDVELDNDSGEPHTN--YDGMKRFRMGTKRNKKGNPIMGRSKTLKWARKNIPNPFEDFTK--DDIDPGAIN-RAQELRTVYYNMPLPKDMIDEEGNPIMQYPRNKIRTTKYTPLTFLPKNILFQFHNFANVYFLVLIILGAFQIFGVTNPGLSAVPLVVIVIITAIKDAIEDSRRTVLDLEVNNTKTHILEGVENENVSTDNISLWRRFKKANSRLLFKFIQYCKEHLTEEGKKKRMQRKRHELRVQKTVGTSGPRSSLDSIDSYRVSADYGRPSLDYDNLEQGAGEAN-------IVDRSLPPRTDCKFAKNYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIRTSKD-IARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITINNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELNFSVVINFVLLFILCFVSGIANGVYYDKKG-RSRFSYEFGTIAGSAATNG------FVSFWVAVILYQSLVPISLYISVEIIKTAQAAFIYGDVLLYNAKLDYPCTPKSWNISDDLGQVEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRKRQGIDVETEGRREK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEIAKDRDTMIDELRALSGNSQFYPEEVTFVSKEFVRDLKGASGEVQQRCCEHFMLALALCHSVLVEANPDNPK------------------KLDLKAQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQKEFEILNILEFNSSRKRMSCIVKIPGLNPGDEPRALLICKGADSIIYSRLSRQSGSNSEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAASLANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEMELLVIKTTGDDVKEFGSEPSEIVD-----------------ALLSKYLKEYFNLTGSEEEIFEAKKDHEFP----------------------------------------------------KGNYAIVIDGDALKLALYGEDIRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGDGSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNTYVLLHQYRWDWFSGLFIALSCLVVFAWTGIWSS------AIASREFFKAAARIYGAPSFWAVFFVAVLFCLLPRFTYDSFQKFFYPTDVEIVREMWQHGHFDHYPPGYDPTDPNRPKVTKAGQHGEKIIEGIALSDNLGGSNYSRDSVVTEEIPMTFMHGEDGSPSGYQKQETWMTSPKETQDLLQSPQFQQAQTFGRGPSTNVRSSLDRTREQMIATNQLDNRYSVERARTSLDLPGVTNAASLIGTQQNN-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : * * *:*:** :.*:* *:: **:.:** **: *:.* . :. : :**: :: :* ** :* * * ::** * . .. * *:***::::.*:. :.** :***:*: . ::** :********.:*.:. : : : : : : .: *: * : *.: : :.:***** :***.*. *:*:: * :**:* *.* : * : :.: :*. :: . :* :* .: .:: . : *: *: :::******:*:*::: :: * * :: : . .:: .:.::***::*:*********:*:* *::*:*** :** . . . .. : .: :: :: *: *:***: : * : .* :******.***:::*:.*: * : . : : * :.:* :*:*.. ***** *:: * *****.:**. * . : * :*:.:* ****** :* : * : * : :: .** :* : : ** :: *:* :*:**:** **. * * :* **:******* *** **.:**.:: ::: :.: . : . .: : .. : : . :.:::.* :* .* . . ::* . *: *:***::* *** **.*:* ..:*******:**:.**::*.:*:**:.:** **.:.**::: **::: **:****: .* *:. :: *****. *:: **.:: .*... ::: :: .*** :*::*:: :.::::**. *: *.** * :. * *.. : *.: *:.* . . :* . .. . : : : * . * : : . * . : : : * . . * : : :: . * : ", "identical_positions": 273, "similar_positions": 335, "identity": "14.16%" }, { "cls_id": "homologset.agr.MGI:2444289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LU03-1", "uniprot_id": "A0ABK0LU03_RAT", "id": "A0ABK0LU03-1", "name": "", "aln": "MNERSCGMNLHRTSRTPQRPGLLSGQHVLPARAHSGTPCSSSCASTPSPTLGSLANSLHLKMSSGAGMAPQSNMAASPIHLPALSPRRQLLANGKPQFQVTQAGVMAASHTLKPKQQEFGDPFSPNPEKGALGFGPQCKSIGKGSCNNLVVTSSPMMVQRLGPISPPASQVSTACKQISPSLPRAVNAVNLNRPPSDT-RSVILQESLVSTTLSLTESQSALSVKQEWSQSYRGFPSLSSNHSSQNGMDLGDLLSLPPGTPVSGNSVSNSLPPYLFGMENSHSPYPSPRHSATRPHSTRSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSRASPANMSP----QSEVYGHFLGVRGSCIPQSCAVSSGQKGVLVTSGGHTLPGYGEDGTLEYERMQQLEHGGLQPGSGNSMVLQPGLPGQDGQTANMLKTERLEEFPASALDLPSAPPLP-LPPPQGPPPPYHAHPHLHHPELLPHTQSLPLAQAGLEEDGELED-SGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWTGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCKKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLAVQPLQPATSPRDAADR-TVGHSPGPGP------ELYSAPIFASNHSTRSGTAAGAVPPPHPVSHPSPGHNVQGSPHNPSSHLPPLTAVDAGTERFAPPTPSPHHISPGRVPAPQSLLQRAQAPHTQQPPGSLLKPYQPETNSSFQSNGIHVHGFYGQLQTFCPP------NYPDSQRSVPSSSSCSMVPSFEDCLVPTSMGQAGFDVFHRALSTHSGITVYDLPSASSSLFGESLRSGPEDPTFLQLSAVDRCPSQLSSVYTEG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6XP49-1", "uniprot_id": "GLIS3_MOUSE", "id": "Q6XP49-1", "name": "Zinc finger protein GLIS3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MMVQRLGPISPPASQVSTACKQISPSLPRAVNAANLNRPPSDT-RSVILQESLVSTTLSLTESQSALSVKQEWSQSYRAFPSLSSSHSSQNGTDLGDLLSLPPGTPVSGNSVSNSLPPYLFGMENSHSPYPSPRHSATRAHSTRSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGPRASPANLSP----QSEVYGHFLGVRGSCIPQSCAVASGQKGILVASGGHTLPGYGEDGTLEYERMQQLEHGGLQPGPVNNMVLQPGLPGQDGQTANMLKTERLEEFPASALDLPSALPLP-LPPPQGPPPPYHAHPHLHHPELLPHTQSLSLAQTGLEEDGEMED-SGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWTGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCKKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSREQQARKKLRSSTELHPDLLTDCLAVQPLQPATSPGDAADH-TVGHSPGPGPGPGPGAELYSAPIFASNHSTRSGTAAGAGPPPHPVSHPSPGHNVQGSPHNPSSQLPPLTAVDAGAERFAPPTPSPHHISPGRVPAPPSLLQRAQAPHSQQPPGSLLKPYQPETNSSFQPNGIHVHGFYGQLQTFCPP------HYPDSQRTVPPSGSCSMVPSFEDCLVPTSMGQAGFDVFHRAFSTHSGITVYDLPSASSSLFGESLRSGPEDPTFLQLSAVDRCPSQLSSVYTEG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEA6-1", "uniprot_id": "GLIS3_HUMAN", "id": "Q8NEA6-1", "name": "Zinc finger protein GLIS3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MMVQRLGLISPPASQVSTACNQISPSLQRAMNAANLNIPPSDT-RSLISRESLASTTLSLTESQSASSMKQEWSQGYRALPSLS-NHGSQNGLDLGDLLSLPPGTSMSSNSVSNSLPSYLFGTESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSRASPANLSP----QPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAPPLPPLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDG-IGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPATSPRDAAAEGTVGRSPGPGP------DLYSAPIFSSNYSSRSGTAAGAVPPPHPVSHPSPGHNVQGSPHNPSSQLPPLTAVDAGAERFAPSAPSPHHISPRRVPAPSSILQRTQPPYTQQPSGSHLKSYQPETNSSFQPNGIHVHGFYGQLQKFCPP------HYPDSQRIVPPVSSCSVVPSFEDCLVPTSMGQASFDVFHRAFSTHSGITVYDLPSSSSSLFGESLRSGAEDATFLQISTVDRCPSQLSSVYTEG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1B7-1", "uniprot_id": "A0A8M6Z1B7_DANRE", "id": "A0A8M6Z1B7-1", "name": "", "aln": "-------------------------------MDMNGKGCNLMVSPS------GMAQISPLKVHTPASLYPESNSAQS--------LRRQVLTNGKLGFPQ-------PSRALHQQAPQISLPASSSSKQSAR----QCCQDSGMKGYRRVFGSCGSSNLQVSSSAFLVQSLSPASASVTHSSSQTCPQNTLTLPFNDASRCLLSRESLASTTLSLAETQSVRSSKLDWPYGYRVLPPLG--HQTANQLSES---TVPESSLSESVSNPASLPHYLFKEDGS-----SPR------LSARSKKRALSLSPLSDGLGLDLNSIIRTSPTSLVAYIIGSRISPASHNTPSPLQADVCGHLLGIRGSGIP-----TSSKHSISVS---------------ESLRMQPLED-----QFTNLLVEQQILP--DPQTAKASQTHTLQFEVSRIVRSP--------SPPRGPPPPYSAHHQQQQQPRVLQLQRPAGLQPMLEEEEEEEESCGGTHCCCWLHCGAIYSHRDALVKHIEKIHVDQRKGEDFTCFWAGCARKHKPFNARYKLLIHMRVHSGEKPNKCSFEGCQKAFSRLENLKIHLRSHTGEKPYVCPHPGCLKAFSNSSDRAKHQRTHVDTKPYACQIQGCGKRYTDPSSLRKHVKSHSLKEQQARKKLRRSSDLSQDGLSECLTVQPLQHSLSTLDLIES----KHHSPTD------DLYT--VFTLNQPSQTNTLN------SPMQIAGGPQTHQSPHQTHQAHQIHQTQTHLTHQTHQAHQTQTHHIQ--QIHQTHLTHQIQQIHQTHLSPHGALPPLQ-GNNRFLSPNSHKAPGFCSQPRTSAQDGFSAVFSYADSDKHIS-SCSVMQTPMFEDNLSSSPQ-------IHSNIS-----AVLDCQSGPQGFIGEQEPSVSED-NYLHIP---RCPSRISCVFTEG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : ...:*.*. .:: * :: .*. * .*: *.:: :***.******:*:**. * * :*. .** :*.*. * : * . . ::* .: .. * . *** *** :.* *** *:***************:*:*:*:************* *.* ***. .. *.:* **:**:*** ** ...::.: *: * *** **. * :* * ** * *:* :*. *: . : * .** ****** ** : :: : * . *. *::: * : **.*** *:.*.*:*.::: **:****:*:************:**.*::************************:****:**********************:* **** ****************:********* ** **************:** :********* *::* * *::**:**.** : *. * : .* :**: :*: * .:::.* *:. .. :. *.. :. .:: * .. : . . ...***. :: . * * :: .. . * . * .* :..*. :. ** .* :. . *.**:: :. * .* *** * .:. :* :* :* * *....::**. * .** .:*::. ****::*.*:***", "identical_positions": 320, "similar_positions": 197, "identity": "33.72%" }, { "cls_id": "homologset.agr.MGI:2444298", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZC11-1", "uniprot_id": "D3ZC11_RAT", "id": "D3ZC11-1", "name": "", "aln": "---MNENKPG---NSQSLACVFCRKNDDCPNKYGEKKTCEKWNFSVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCTVCKKNGASIGCVVPQCKRSYHLPCGLQKECIFQFTDNFASFCWKHRPVQAITSNKYRDS---LPCTICLEFVEPIPTYNILQSPCCKNAWFHRDCLQVQAINAGVFFFRCTLCNNTDIFQKEMLRMGIHIPEKDASWELEENAYQELLQSHDRCDVRRCHCKEGREYNEPNSKWEIKRCQCCGSSGTHLACSSLQSWEKNWECLDCRRIAYTS-DFQKAPKHPLANSTNVTVTDCLLEESSPKLPRQSTVAQ---QKELLSLKQEVQLSSTTCPSRKASCLTQRQGSKFRRDISTILIELGFQIKKKAKTLYIN---KANVWRSAVEQFQSQKFNPSYSIEVVYVNDNDEVGSKHPGSKQEFLSHLMHHLENSSVFEGS-LAKNLSLNSQAVKENLYYEAGKMLAISLVHGGPSPGFFSETLFKCLAYGPENALPTLDDVSDLDVAQIIIKIDTAADLNILKSVINEYYNYLEFSGCLRLMTTLSDKYMLVKDILFYQVIKRVKAPFESFKQGLKTLGVLEKIQAYPEAFYNILCHKPESLSAKNLSDLFTIHK-------LPDVKTSRFWNSYLQAVEDGKSATTLEDILHFATGCSSVPPTGFKPAPSIECLH-----GDFPVANKCNNCLALPVTNTYEEFQENMDFAIRDSIRLEKEERSHLLPRTLNVSSNEEMLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5RJY2-1", "uniprot_id": "G2E3_MOUSE", "id": "Q5RJY2-1", "name": "G2/M phase-specific E3 ubiquitin-protein ligase", "aln": "---MNENKPD---NSQSLACVFCRKNDDCPNKYGEKKTYEKWNFSVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVQRASKLKCTVCKKNGASIGCVVPTCKRSYHLPCGLQKECIFQFTDNFASFCWKHRPVQAITSNKYSSS---LPCTICLEFVEPIPTYNILQSPCCKNAWFHRDCLQVQAINAGVFFFRCTLCNNTDIFQKEMLRMGIHIPEKDASWELEENAYQELLQSHDRCDIRRCHCKKGRDYNEPNSKWEVKRCQSCGSSGTHLACSSLQSWEQNWECLDCRRITYTS-DFQKAPKHPLANSTNVTVTDCLLEESSSKLPRQSTVAQ---HKELL-----------------------RQGSKFRRDISTILIELGFQIKKKTKTLYIN---KANVWRSALEQFQSQKFNPSCSIDVVYVNGN-EVGSQHLGSKQEFLSHLMHHLENSSVFEGS-LAKNLSLNSQAVKENLYYEVGKMLAISLVHGGPSPGFFSETLFNCLAYGPENTLPTLDDVSDIDVAQIIIKIDSATDLNILNSVISQHYNYLEVSGCLRLTTSLSDKFMLVKDILFYHVINRVKAPFESFKQGLKTLGVLEKIQTYPEAFYKILCHKPENLSAKNLSDLFTIHS-------VADVQTLRFWNSYLKAIEDGKSATTMEDILIFATGCSSVPPTGFKPSLSVECLH-----VDFPVADKYRNHLVLPATNTYEEFQENMDFTIRDTLRLEKEERSHILPRTLNVSSNEEMLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L622-1", "uniprot_id": "G2E3_HUMAN", "id": "Q7L622-1", "name": "G2/M phase-specific E3 ubiquitin-protein ligase", "aln": "---MNESKPG---DSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNFASFCWDHRPVQIITSNNYRES---LPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRCKEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKKHVLPNSNNVGITDCLLEESSPKLPRQSPGSQ---SKDLL-----------------------RQGSKFRRNVSTLLIELGFQIKKKTKRLYIN---KANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHLENSSLFEGS-LSKNLSLNSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPENTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLVKDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFTVHT-------LPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLH-----VDFPVGNKCNNCLAIPITNTYKEFQENMDFTIRNTLRLEKEESSHYIGH------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8AW58-1", "uniprot_id": "Q8AW58_DANRE", "id": "Q8AW58-1", "name": "", "aln": "MKALNEKSAEIKLQDRDLICCLCKRSENNKEKYGEKVHLEQHNLAVHFFCLLMSSGICQRGEEDEDVYGFLVGDIKKEIRRSSRLRCFHCKKAGASVGCSIKSCRQMVHMPCGLEQEFVFQFTGLFPSFCKKHAPTQSCDS-SHSLP---HSCSICLDPIEPILSYHVLKCPACHGSWFHRKCVQNYAHSAAMFFFKCTLCNNKEQFQQEMLRMGIYIPERDASWELEENAFVELLQVYHRCDAVKCLCHKGREHSSQSGYFEIVLCKLCGSRGTHRKCSNIRVYEADWMCADCK--------TAAEGKTSLPLPNHVESPLAIRQERKRLFKSISDIHSSIVAK--------------------------RQCVPATS--PEVLMDLACQISQQQFTEVLVGDDDGGVMEAALQVLRQSDFNPCCTLSVKFSKDK---LNNNIRNQRRFLRRLVSKLQVSDIFEGSDGAKNLALNSKALRDDLYFDVGSLLALSLVHGGPPLGFFSPALYHSLFNYPKNYRPTLEDLGDTAFGHKIRQIAEAKSMKELRHAMKSASQYLEAAGCWRKISKLSEKDMLVEDVLNFYLIIRLQLPLQRFREGLRTLGMFEQVQMCSETFFPVFCGPVERLTAESVMELFTTRLSEEKEKQVLEKTTISFWKQYLHECEEGQCAASLEDLLTFATGTDLVPAIGFKPTPSISFLSSPDNLCAFPQSNCDANHLILPTLPSYQLFKKHLDYTVCQFSVMQDI--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKW2-1", "uniprot_id": "PIE_DROME", "id": "Q9VKW2-1", "name": "Pineapple eye protein", "aln": "---MED--------NKELQCLICKYSDTDDLVFGEWMIVR--NLQVHYFCLLLSTHLPQRGGDSSGILGFLLRDIREEAAAAEKRKCWYCNKIGASLQCDR--CRSLFHLKCGLENRAVFEFCGQYKSYCYKCRPMDDYKRQLQSNPPRNATCPICFSSIYKVELHCVVYGDCCRLGFAHKKCMRQYALTSG-YYLRCIWCR-SERFRDSIRLQSVFVPDRDATWEKQRNAYRELHERNLKCDQPNCLCPSGRTYNRLS--WVILCCSSCAATSAHLKCLVGALRLP-----------------KKRERTDFKCSMCLDVERRIAEGPARTTEETNADGD-------------------------------------------NQVDGSFYVQKLGPDAATR------SLTQTPVFSEEDESERSSNITVIFSQPKSNATSERLSLSPPQEEMIVEIPDSPEASPKTSIDENHSPQPIARRDTS--DSPQPIAASEIPDSPQP----------------TAASEIPDLPQTTAINVNPELTQQTALNTIPHSPQPEASFSTQLVSQTFDCPQPQEQAVAKAPNSPSLPKEDPNTLLVLKSGFQCP---------GEPFFYLVIY------------------------------------EFEHGTCMGECIG--TCVLRFKEDDPRIQDTSQAALERVNITP-------DDVWCRSEDRGIFEHIEKFHEWYRSEGFS------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: .:.* * :*: : :** . *: **::***:*: : *** :...: ***: **::* :.: :* *:* ***: * *: *: ***:.. :*:* . : *:* . * : . .*.**:. : : : :: .*: .: *:.*:: * .:. ::::* *. .: *:..: .:.:*::**:** :.**: ** : :** .* * .** :. . : : *. *.: .:* * : : . : : : . . :: . :.: : .. . : . : * : : .:. . :: : .. : :* : :. * :: : . :* * : ..* . . : *: : : .: : : . .: . .:: :.: : . .: ::.*:: *.* :. .: : *:. :* * . : . . :. : : .:. : . .:: ", "identical_positions": 80, "similar_positions": 198, "identity": "10.4%" }, { "cls_id": "homologset.agr.MGI:2444300", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80Y19-1", "uniprot_id": "RHGBA_MOUSE", "id": "Q80Y19-1", "name": "Rho GTPase-activating protein 11A", "aln": "--MWDQRLVRLALLQQLRAVYGIKVKGGRGQCDRRRHETAATEIKGKVFGVPFNSLPHSVVPEFGHIPSFLVDACASLKEHIHTEGLFRKSGSVVRLKALKSKLDQGEACLSSALPCDVAGLLKQFFRELPEPVLPADLHEALFKAQQLG-AEERNKATLLLSCLMANPTVDILRYFFNFLKSVSLRASENKMDSSNLAVIFAPNLLQTSEGHEKMSANTEKKLRLQAAVVQTFIDCASDIGRVPDFILEKIPAMLGIDGLCTTPSLEGF-EGDFETPGECKRKRRQSVGDFVNGALNKLKSSRTPSITPQQDRTAQASASPLILTPSVKRKLPGESS--HAFSSKKRKSIKHNLNFELLPSHFFSSNSTPVSVHLDTSPDGSSQTSLSPIAMSGNHLVSTEL-RRSKRIASKKVYRVESGKAGCFSPKVSRKEKTRRSLRLKFSLGKN-RDSDGCSVIN----RYENVGRRLANQQNLKSRIDSVKTGLLFSPDIDERLLKKGSEKISKSEEHLLTPDQLDGTGYRMSWTEPSNSSFQDMSANGTSPIMQNLEVKSFSLEPDITVEKSPVVSCELRPSTFHSQPDSSVL--SLSGDEGNLASETLQKIQKAFSESGSDLHMVINHEQSSVTNTG--------------EE--VEFRDVTVTESKGHDGSCAGEEENCPSERNFSPDQSPEFAREADEECYSTQMKVECEG-LHSETPKADPLILQAFPGEEPAEEPQSPRNQLS-TPSRGNENGGE-SAGASGAPGED--------ESTCSVAVLSKPRPQRLSRQQSLVEKCDSVAPGALQVTEHGKVSDHIQWFNKLSLNEPNRGKVKSPLKFQRTPVRQSVRRINSLLEYGRQPVRQKLAIFGDAASPLVKSVSCDSALPSCVQNTSKGPTAPLITSGLEAQKSTSCN--------KSSVELTSKSFTKMKRHPDPLSASLGTPRLCKQENKSNGHIKFPLDDLTNHERLKFVVNNNVAFSPGMKNRVVRKPSEKERVWYKGSPKNPIGKTQLLPTSKPVDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z951-1", "uniprot_id": "D3Z951_RAT", "id": "D3Z951-1", "name": "Rho GTPase-activating protein 11A", "aln": "--MWDQRLVRLALLQQLRAVYGIKVKGGRGQCDRRRQETAATEIRGKIFGVPFNSLPHSVVPEYGHIPSFLVDACTSLKEHIHTEGLFRKSGSVIRLKALKSKLDHGEACLSSALPCDVAGLLKQFFRELPEPVLPADLHEALFKAQQLG-AEERNKATLLLSCLMADPTVDVLRYFFNFLKSVSLRASENKMDSSNLAVIFAPNLLQTSEGHEKMSANTEKKLRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGIDGLCTTPSLEGF-EGDYETPGECKRKRRQSVGDFVNGALNKLKSSRTPSITPQQDRTAQAPVSPLILTPSVKRKLPGETS--HTLSSKKRKSIKNNLNFELLPSHLFSSNSTPVSVHFDTSPEGSSQSSLSPIAMSGNHLTSTDL-RRSKRIASKKVYRVESGKAGCFSPKVTRKEKVRRSLRLKFSLRKN-RDSNGCSVIN----RHENVGRRLANQQNLKNRIESVKTGLLFSPDIDERLLKKGSEKISKSEEHLLTPDQLDGTGYRMSWTEPSNSSFQDMSANGTSPIMQNLEVKSFSLESNITVEKSPVVSCELRPSTFHSQPNSSVLGRSLSGDEGNLAFETLQKIQKAFSESGSDLHTAVNHEQSSVTNVG--------------EE--GESRD--VSESKGHDGSYTGQDENYASERNLSPSQSPELAREASEECHSTQMKVGCES-LHSETPRAD-LLQQAFPSEEPTKETQSPGSQLDTTPSQGDENVVEENSGACEAPEENDAQS--LKQSTCSVTVISKPRAQRLARQRSLVEKCDSAVPGGPQMTEHGKVSDHIQWFNKLSLNEPNRGKVKSPLKFQRTPVRQSVRRINSLLEYGRQPVRQKLAVFGDAASPLVKSVSCDSALPSCVQSTSKGPCVPHTKPGLEAQKCTSCD--------KSSVELTSKSFTKMKRHPDPLNASLATTRLCKQENKSDVQIKFPLDDLTNHDRLKFVVNNNVDFPPGIKNRVLKKPLEKERVWYKGSPKNPIGKTQLLPTSKPVDL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P4F7-1", "uniprot_id": "RHGBA_HUMAN", "id": "Q6P4F7-1", "name": "Rho GTPase-activating protein 11A", "aln": "--MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLG-TEEKNKATLLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPNRTPSITPQEERIAQLSESPVILTPNAKRTLPVDSS--HGFSSKKRKSIKHNFNFELLPSNLFNSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGCFSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVN----RYESVGWRLANQQSLKNRIESVKTGLLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRMSWTGPNNSSFQEVDANEASSMVENLEVEN-SLEPDIMVEKSPATSCELTPSNLNNKHNSNITSSPLSGDENNMTKETLVKVQKAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSPEENLFETNDLTIVESKEKYEHHTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEHEKDIHSNMPKDY-LSKQEFSSDEEIKKQQSPKDKLN-NKLKENENMMEGNLPKCAAHSKDEARSSFSQQSTCVVTNLSKPRPMRIAKQQS-LETCEKTVSESSQMTEHRKVSDHIQWFNKLSLNEPNRIKVKSPLKFQRTPVRQSVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGALSSCIESASKDSSVSCIKSGPKEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVNASLRSTTVYKQKILSDGQVKVPLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRAWYKGSPKHPIGKTQLLPTSKPVDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ILK3-1", "uniprot_id": "A0A0R4ILK3_DANRE", "id": "A0A0R4ILK3-1", "name": "", "aln": "MRVLERNVVRLAVVQHLRSVYGIRIKNWN---KNRSKQTSANTVR--VFGVALEGLPHSHVLDYGDLPCFLVDICTTLLDHLDTEGLFRKSGSVVRVKSLRAKLDQGEDCLSAALPLDIAGLLKQFFRELPEPVLTVDLHSAFLKAQELPTAEERTSATVLLSCVLPDTNLNTLRYFFSFLKTVSQRCAENKMDSSNLAVIFAPNLFHCGDGGEKMSSSTEKRLKHQAAAVQCLIENAQRIGVVPQFLMEKVPAMLGCDAAVFSPSAVSP--EDSNAHFDLKKSNRRSLGDVVNGALNRLKASRTPTNTPHSDGAVFSMATPVIMTPNSKRKLPLESSQTHGFSNKKRRSIKKNLGLELFPSVLFGGTSTPGSTHSAAGVLDSSHSGLLSSVGRNSRLSSSSARRKSRRLRDRSVSRVESGKAGCFSPRTAKKEPVRKSLRLRFSLGKSSRDSNLITHSQPVPKGSEVIGWRLATQESSTG----FHFTKELSLPVLSKSPSKGSKFFSKSEDNLSTP-QCDFTDHRSSWTG------------ETPETGLTFPTDSFSETPLIIVSKPPTISSVPET----------------TPEECSHTGHTLLKIRQAFGESGSDLHSIITQKDQQDDSSN--------------------VHLPSETAHKSISESGQSNDDVTFGQIEIVPLSPLHIDSALFDSEPTRFVETSLNG---SLCFKNEYLKESAVRSVNCSQIIDALDIQSPVAFRLDTSTRVQSTPYATRS------------QVNANTSLQDELRASSLVEKKIESSQEQQNNAES----KKSKVADQIKLFNMMTLHSPKVQLLRSPLKFQRTPVRQSVTRINSLAGKRKE------SRMGWCAASQVKAVSLESGLYSSVKPK---PPVPLKKTAVKP---------------------------------------------------------AALEDITN-KAPKAMLSNCKNAADEHPKCVLLKVSENDTSHYRGSPRHPLVEGRLLSAMKPIDL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::.:****::*:**:.***::*. . ..* ::*:*. : :***.::.**** * ::*.:*.**** *::* :*:.***********:*:*:*: *:*:** ***:* * *:**************:*..***.*::***:* :**:..**:****::.: .:. *****.**:.** *.:*****************:: .:* ****:.***:*: ***.** :*: *. ** **:*::**:***** *. :** . : :: : *:..*:*:**.*.****::*..***: **:.: . :*:*:**. **.** ::* * :*.***:***:*:.:**:** :*...*** *.* :. .**::.* . ..:* :: *:*:*: .:.* ************: ::** .*:****:*.* *. *: : : : * :* ***.*:. .. .: :* : .: .***: :****: * ** : *.:* *** :. .: ... * . * *.*.*. *. . : :* . : .** *:::**.****:** :.:.:.. . . . * .: : .: :: * .. : . : :: : * : * . . . : : :: : .. : . : : .. .: .: *. : .:: . :. . . :: **:*:*: ** ::*:.*: ::************** ***** :: : :* *:. **:** :..* *.:: . .. ... : .*:*:** . * ::.* . : *: : *. *:***::*: : :**.: **:**", "identical_positions": 318, "similar_positions": 308, "identity": "30.69%" }, { "cls_id": "homologset.agr.MGI:2444304", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A4A2-1", "uniprot_id": "A0A8I6A4A2_RAT", "id": "A0A8I6A4A2-1", "name": "", "aln": "MVFESVVVDVLNRFLGDYVVNLDQSQLSLGIWKGAVVLKNLVIKENALHELDVPFKVKVGRIGSLQLKIPWKNLYTQPVEAVLEEIYLLIVPSSRIQYDPIKEEKQLMEAKQQELKRIEEAKQKVVDQENPR--------EEKQDTFAEKLVTQIIKNLQVQISSIHVRYEDDI-TNREKPLSFGISLQNLSLQTTDQYWIPCLHDDTEKLVRKLIRLDNLFAYWNVNSEMFYLNDY-----DDALEALKNGIVNENIIPEGYDFVFRPISANAKLQMNRRSDFD---FSDPKINLDIELHTIVIEFNKPQYFSLMELLESIDMMTQNLPYRKFKPS-VPLHLHAEEWWAYAIHGILEVNVCPSLRMWSWEHIKNHRYKMKQYREFYKKKLTNKKPSPEILMSLEELEKTLDVFNITIARQQAEVEVKKAGYKIYKEGLKDPED-NAGWFS-WMWSWSESNAN---------QQQ-DVKPGILAEMLTPEEKALLYEAIGYSETAVDP---TLPKTFEALKFFVHLKSMSIVLREN-----------RQKPELLNVVVEGLSTSIVQRPGAQALKFETKIDSFHITGLPDDFKKPHLLSSLDD-----------------MSLFRITFEINPLDETVSQRCTIEAEPLEMIYDARTVNSIVEFFRPP--KDVRLAQLTTATLTKLEEFREKTATGLLYIIETQKVLDLRINVKASYVIVPQYGNFSP-TSNLLLLDLGHLKVTSKRRSG--------LPDVKPSGASLEDIMHRAYDSFDIQLSSIQLLYS-RVGDNWKEARKLN-VSTQHILIPMHVNIELSKAMVFMDIKMPKFKIFGKLPLVSLRISDKKLQGIMELLESIPKPEPVTDVSAPARSFQIQAS-TMPVSHISQKLIPLLEQS-ATEDDSEEE-FFDAPCSPLEEYPQVSCRVESTRRKKLQK------KDGSMNFIQLSMRFEVAEVLIQFYHLVGDCELPVLEMGVLGLGTEVEIRKFDLKGNAFLKELWLKCPGYLDEHKKPVYLITT----LDNTMEDLLTLEFMRVEKNAPNLNSTYNNVLQLIKVNFSSLDIHLHTEALLNTMNYLNNILP----ELGETSASVSAAEPEDKGD--------------------IIKKLALKLPTNEDIITLQLLAELSCLRIFIQDQKQNISEIKIEGLDSEMIMKPLVTEINAKLRNIIVLDSDKMAVYKKAVYITGKEVFSFKMISYMDATAGYAYTDMSVVDARVYLTVGCIEVVFVTKFLYSILAFINNFQAVKNALAEATVQAAGMAADGVKELARKSSRFALDVNIKAPVVLIPQSPVSRNVFVADFGLITIKNIFVTVTE-TQSNIPPVIDLITIKLSKMRLYRSQFMNN------------TYQEVLDLLLPLNLEVIVERNLSWEWYKEVPCFNIKAQLKPMEFILSQEDLTTVFQTLYGN---IWYGRDVPAPSSVNKGPEIMTTEVTS-TSYHSG-ATMVTSAVVEVHPQASPANTTLNVSFQTDHLIMTLYS---PGPDQASFTDVRDPSLELAEFKLENIISDLKVYTDDSMVFSFSLKNCILDDKRPHVMKATPRMIGLTVGFDKKDMVDVKYRQIRDV--FVTDVVVQEMYVCASVEFLMTVARVFFDAYMT-------------------------STALETSVQTWTTR-EAPVQELRKWEMNILIKNPEIVFVADMTRNDAPALVITTQCEICCKGEPESNTVTAAIKDFQVRACPFLPVKRKGRVTTVLQP-CDLFYQATQFGTDPQTIDISVKSLTLKVSPVIINTIITVTSALYT--TKETVPEESTS--------NVAHLWDKKDTKNLKMWFLEESNETEKVVPTDEVMPGG------ETLNLNIDSIFIVLEAGIGHRTVPMLLAKSSFLGESKNWRTLINLHCQLELEVHYFNEMFGVWEPLLEPLEIDQSDDFRPWNLGIKMKKKAKEAIVESDSEEENYKVPEYKTAISFFSRDQLNITLSKCGLVMLSNLVEAFTEAATGSSAVFLRDLAPFMILNSLGLTVSVSPSDSFHVLN-VPLAKSYELKNEESLSMDYVRTKDN------------------DHFNAMTSLSSKLFFILLTPANHSVADKIPLTKVGRRLYTVRHRESGVERSIICQIDTVEG-SKKVTIRSPVQIKNHFSIPISVFEG----------DTLLGIASPENEFNIPLASYRSSLSLKPE---DEDYQLCEGIDFEEIIKHDGQLLKKKCRSISPSKKSFVINIVPEKDNLASLSAYSEDGWDLPYVMHLWPPILIRNLLPYKIAYYLEG-IENT-VCTLSEGHSSQIYN--------------------------------VEMDQAKLHLKLLDYLNHDWKSEFQIDPNQQDINFINFTCLTEMEKSD----LDIAIHMTYNTGQTVVAFHSPYWMVNKTNRMLQYKADG-------IHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSDQFSIDTVGSHGAIKCKGLKMEYQVGVTIDLS----SFNITRIVTFIPFYMIKNKSRYHISVTEEG--SDKWLSLD-LEQCIPFWPENASDILLIQVERSEGPPKRIYFNKQDSCILLRLDNELGGVIAEVNLAEHSTVITFSDYHEGAATFLLINHTKSDPVQYNQS-----------------SLSEIEDSLP---------PGKAVYYTWADPVGSRKLKWSCGQSYGEVTHKDDMMTPISVGKKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELAELEVVLALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKSRWKPMSVKHTEKLEKEFREYTESSPL-EDKVVELDNSIPVLLTPSGNDMKILEPHVIAVRRNYLPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGAIFPFVFYPIKPPRSVTMDSAPKPFTDVSIVMRSAGHSQISRIKYFKVLIQEMDLRLDLGFVYALADLVP---KTEVTEKTEVEYFHRDVEAFEQEFEVVSSVD--QSQVNLFEYFHISPIKLHLSVSLSSGRDEAKDTEQHGGLIPVHSLNLLLKSIGATLTDVQDVVFKLAFFQLNYQFHTTSELQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGVEAFFYEPYQGAIQG--PEEFVEGMALGLKALVGGAVGGLAGAASKITSAMAKGVAAMTMDEDYQQKRREAMNKQPAGLREGITRGGKGLVSGFVSGITGIVTKPIKGAQKEGAAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRATETS-EVESLRP--PRFFNEDGVIRPYRLRDGTGNQMLQVMENGRFAKYKYFTH--VMVNKTDMFMITRCGVLFVTKG-TFGQLTCEWQYTFDEFTKEPFIVHGRRLRIEAKER-VKSVFHAKEFGKIINFKTPEDARWILTKLEEAREPSPRL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5H8C4-1", "uniprot_id": "VP13A_MOUSE", "id": "Q5H8C4-1", "name": "Intermembrane lipid transfer protein VPS13A", "aln": "MVFESVVVEVLNRFLGDYVVNLDESQLSLGIWKGAVALKNLVIKENALHELDVPFKVKVGHIGSLKLKIPWKNLYTQPVEAVLEEIFLLIVPSSRIQYDPIKEEKQLMETKQQELKRIEKAKQKVFDKEKPR--------EEKQDTFTEKLVTQIIQNLQVQISSIHIRYEDDI-TNGDKPLSFGISLQNISLQTTDQYWIPCLHDNTEKLVRKLIRLDNLFAYWNVNSEMFYLNDY-----DESLKALKNGIVNENIVPEGYDFVFRPISASAKLQMNRRSDFD---FSDPKINLAVDLHTIAIEFNKPQYFSLMELLESIDMMTQNQPYRKFKPS-VPLHLHAKEWWAYAIHSILEVNVCPSLRMWSWEHIRNHRYKMKRYREFYKKKLTSKKPSPEILMSLEELEKTLDVFNITIARQQAEVEAKKAGYKIYKEGVKDPED-NAGWFG-WLWTWSESNAN---------QQQ-DVKPGILEEMLTPEEKSLLYEAIGYSETAVDP---TLPKTFEALKFFVHLKSMSIVLREN-----------HQKPELLNVVVEGLSTSVVQRPGAQAIKFETKIDSFHITGLPDDFKKPHLLSSLDD-----------------TSLLQITFEINPLNETVAQRCTIEAEPLEIIYDARTVNSIVEFFRPP--KDVHLAQLTSVTLTKLEEFRAKTATGLLYVIETQKVLDLRINVKASYVIVPQYGNFSP-TSNLLLLDLGHLKVSSKRRSL--------LPDVRPSEASLEDIMHRAYDSFDIQLTSIQLLYS-RVGDNWKEARKLN-VSTQHILIPMHVNVELSKAMVFMDIKMPKFKISGKLPLVSLRISDKKLQGIMELLGSIPKPEPVTDVSAPARSFQIQAS-ALPVSHISQKLIPLLEQP-VTEDDSEEE-FFDAPCSPLEECPQVSCRDKCTRQKKLQK------KDCVMNLIQLRMRFEVAEVSIQFYHLVGDCELPVLEMGALGLGTEAEFRTFDLKGSAFLKELWLKCPEYLDENKKPVYLITT----LDNTMEDLLTLEFMKVEKNAPNLNSTYNNVLQLIKVNFSSLDIHLHTEALLNTMNYLNNILP----ELREKSASVSAAEPEDKGD--------------------IIKKLALKLPTNEDIITLQLLAELSCLQIFIQDQKQNISEIKIEGLDSEMIMKPLVTEINAKLRNIIVLDSDKMAIYKKALYITGKEVFSFKMISYMDATAGYAYTDMSVVDIRVHLTVGCIEVVFITKFLYSILAFIDNFQAVKDALAEATVQAAEMAADGVKELARKSSRFALDVNIKAPVVLIPQSPVSQNVFVADFGLITMKNIFVTVTE-TQSNIPPVIDLITIKLSKMRLYRSQFRND------------TYQEVLDLLLPLNLEVIVERNLSWEWYKEVPCFNIKAQLKPMEFILSQEDLTTVFQTLHGN---IWYGQDLSAPSSANKDPETMTSGVTS-PPDHSP-ATVVTAAVVEVHPQASQAHTMLNVSFQTDYLTMALYS---PGPDEASFTDVRDPSLELAEFKLENIISSLKIYTDDSTVFSFSVKNCILDDKRSHVMKATPRMIGLTVGFDKKDMVDIKYRKIKTF--VVTDAVVQEMYVCASVEFLMTVAHIFFDAYMT-------------------------STALETSVQTRTTR-EAPAQELGKWEMNILIKNPEIVFVADMTRNDAPALVITTQCEICCKGEPTSNTVTAAIKDLQVRACPFLPVKRKGKVTTVLQP-CDLFYQATQLGRDPQMIDISVKSLTLKVSPVIINTIITITSALYT--TKETVPEENTS--------NIAHLWDKKDTKNLKMWFLEESNESEKVVPTNEVMPGG------ETLNLRIDSIFIVLEAGIGHRTVPMLLAKACFSGESKNWLSLINLHCHLELEVHYYNEMFGVWEPLLEPLEIDQTDDFRPWNLGIKMKKKAKEAIVESDSEAENYKVPEYKTAISFYSRDQLNITLSKCGLVMLNNLVEAFTEAATGSSSVFLRDLAPFMIFNSLGLTVSVSPSDSFSVLN-VPLAKSYELKNDESLSMDYVRTKDN------------------DHFNAMTSLSSKLFFILLTPANHSVADKIPLTKVGRRLYTVRHRESGVERSIICQIDTVEG-SKKVTIRSPVQIKNHFSIPISVFEG----------DTLLGIASPENEFNIPLASYRSSLSLVPE---DQDYQLCEGIDFEEIIKYDGQLLKKKCRSTNPSKKSFVINIVPEKDNLASLSVYSEDGWDLPYVLHLWPPILIRNLLPYKVAYYIEG-IENT-VVTLSEGHSSQIYN--------------------------------VEMDQAKLHLKLLDYLNHDWKSEFYIRSSQQDINFINFTCLTEMEKSD----LDIAIHMTYNTGQTVVAFHSPYWMVNKTNRMLQYKADG-------IHRKHPPNYTKPVLFSFQPNHFFNNNKVQLMVTDSELSDQFSIDTVGSHGAIRCKGLKMEYQVGVTINLS----SFNITRIVTFIPFYMIKNKSKYHISVAEEG--SDKWLSLD-LEQSIPFWPENASNILLIQVERSEDPPKRIYFNKQDNCILLRLNNELGGIIAEVNLAEHSTVITFSDYHDGAATFLLINHTKSDPVQYNQS-----------------SLGEIEDSLP---------PGKAVYYTWADPVGSRKLKWSCGQSYGEVTHKDDMMTPISVGKKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELAELEVVLALQDVGISLVNNYTKQEVAYIGITSSDVVWEAKPKKKARWKPMSVKHTEKLEKEFREYTEASPL-EDKVVELDN-IPVRLTPSGNDMKILQPHVIPVRRNYLPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGAIFPFVFYPIKPPRSVTMDSAPKPFTDVSIVMRSAGHSQISRIKYFKVLIQEMDLSLDLGFVYALADLVT---KAEVTEKTEVEHFHKDVEAFEQEYEVVSSVD--QSQVNLFEYFHISPIKLHLSVSLSSGRDEAKDSEQHGGLIPVHSLNLLLKSIGATLTDVQDVVFKLAFFELNYQFHTTSELQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGVEAFFYEPYQGAIQG--PEEFVEGMALGLKALVGGAVGGLAGAASKITSAMAKGVAAMTMDEDYQQKRREAMNKQPAGLREGITRGGKGLVSGFVSGITGIVTKPIKGAQKEGAAGFFKGVGKGLVGAVTRPTGGIIDMASSTFQGIKRATETS-EVESLRP--PRFFNEDGVIRPYRLRDGSGNQMLQVMENGRFAKYKYFTH--VMINKTDMFMITRRGVLFVTKG-TFGQLTCEWQYTFDEFTKEPFIVHGRRLRIEAKER-VKSVFHAKEFGKIVNFKTPEDARWILTKLEEAREPSPRL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RL7-1", "uniprot_id": "VP13A_HUMAN", "id": "Q96RL7-1", "name": "Intermembrane lipid transfer protein VPS13A", "aln": "MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEAKQKVVDQEQHL--------PEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDI-TNRDKPLSFGISLQNLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDY-----DNSLDDLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSDFD---FSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKFKPD-VPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQKVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEGVKDPED-NKGWFS-WLWSWSEQNTN---------EQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDP---TLLKTFEALKFFVHLKSMSIVLREN-----------HQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLSSLDDA----------------MSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPP--KEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSP-TSNLLLLDLGHLKVTSKSRSE--------LPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYS-RVGDNWREARKLS-VSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEE-FFDAPCSPLEEPLQFPTGVKSIRTRKLQK------QDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTT----LDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILP----QSEEKSAPVSTTETEDKGD--------------------VIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITE-SQSSPPPVIDLITIKLSEMRLYRSRFIND------------AYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGN---IWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYS---PGPKQASFTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDG--CVTDAVFQEMYICASVEFLQTVANVFLEAYTT-------------------------GTAVETSVQTWTAKEEVPTQESVKWEINVIIKNPEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQP-CDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYT--TKETIPEETAS--------STAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKG------EMIKMNIDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLN-IPMAKSYVLKNGESLSMDYIRTKDN------------------DHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEG-SKKVTIRSPVQIRNHFSVPLSVYEG----------DTLLGTASPENEFNIPLGSYRSFIFLKPE---DENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHLWPPILLRNLLPYKIAYYIEG-IENS-VFTLSEGHSAQICT--------------------------------AQLGKARLHLKLLDYLNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTD----LDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQYKADG-------IHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKGLKMDYQVGVTIDLS----SFNITRIVTFTPFYMIKNKSKYHISVAEEG--NDKWLSLD-LEQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTVITFLDYHDGAATFLLINHTKNELVQYNQS-----------------SLSEIEDSLP---------PGKAVFYTWADPVGSRRLKWRCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELAEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLEREFKEYTESSPS-EDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISRIKYFKVLIQEMDLRLDLGFIYALTDLMT---EAEVTENTEVELFHKDIEAFKEEYKTASLVD--QSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGVEAFFYEPYQGAIQG--PEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRATETS-EVESLRP--PRFFNEDGVIRPYRLRDGTGNQMLQVMENGRFAKYKYFTH--VMINKTDMLMITRRGVLFVTKG-TFGQLTCEWQYSFDEFTKEPFIVHGRRLRIEAKER-VKSVFHAREFGKIINFKTPEDARWILTKLQEAREPSPSL-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BET3-1", "uniprot_id": "A0A8M2BET3_DANRE", "id": "A0A8M2BET3-1", "name": "", "aln": "MVFESVVVDVLNRFLGDYVGNLDSSQLSLGIWGGDAILRNLEIKENALSQLDIPFKVRAGHIGRLELKIPWKNLYTQSVEATLDEVYLLIVPTASIKYDAEKEERQLQESRQRELQRIEETKQKAAEKENPK--------GEKQDTFVEKLVTQVIKNLQVKISNIHVRYEDDV-TNPSVPLSFGISLQNLSLQTADQNWNPCLLDEKAKLFFKLVRLDNLFAYWNVSSELYSNHNP-----EEALRYLKHSVAIQTAIPQDYHFIFRPISANAKLRMNPRSDVD---FSSPKMDLVVNLPEVAVELSRPQYVSILELLGSVDMMTRNLPYRKYRPY-VVVHTNARQWWRYVITGVLEVNVKPRLHMWSWLHIRRHRQHVKKYRELYKNKIISKKPAESLLKELEETERTLDIFNITMARQQAEMEASKAGLRIYRPGVKVEEEQSQGWFG-WMWNWSGEASA---------TQTKDVKTGGFDGLMTPAEKAKLYAAIGYSETAVNP---NLPKNFENMKMNFHLLRLSLSIKES-----------REKAEIIKLSVIDLKAMLTQRPAAQAIKISAQLSSFEVSGLPREKSAPILLSPRHVDGM------------KDKSLLNLMFETNPLDARADQRLRIESQPLEIIYDAMTVNSMSAFFMPP--KDLQLDELTNATLMKLEQFRDKTSTGLMYIIETQKVLDLKINLMASYVIVPENGFYDP-KHNLAILDLGHFQMSSQSRAD--------LPQLSAGSSTLEDIMSRAYDSFDVQLSSLQFLYS-KAGGDWKRARPLR-QSAFHILEPVDLKVVFSRAMVVTDSRMPKFKMHGELPLLSLRISDDKVRGVLALLSSIPLPESRPTPQSRNTQATPKASKRGNTPQLTPRRPAIDDLRASIIYGSEEELFFDAPSSPIEDLPFFEASSDSRHASAADKRLSMVLKDPKKNMTEFLLSFEINKLSVQLCRVSNRQEVSVLHLFIDGLGTELKLRTFDMSSYTFLREICLECSEYLDSEDKKVHLITT----LDNTEEDLLTLEYVKADKNAPDFKAMYKNTEQLIKVNFSSLDIHLHTEALLNSMNFLNNLLPPMKKETQEEQPIIPKEEEEEEEEEEEEE-------EAKVENSAVAKKSSYKKSKFEDVVNLHIRADLNCLKVFIRGEKARISEISIEGLVSEVQMKKKSVEILANLKNIIILDCDKEALYKKAVSIADKEVFDFRMVNHVDATEGDAYTDMHIVDTSVTLTVGCIQVIFLNKFMSSILAFINNFQEAKNALAEVTAQAAEKAATGVLELAERSTRISLDVDIKAPVVFLPQSSVSHNVIVADLGLVTVKNRFEIVSSPTHTKIPPVMDIMAVGLSDLKMYRTTFTDD------------KFNSEIQLLKPVNMDLSIKRNLSASWYHSIPDIQINAHLKPMSLILSQEDLTVVLKTLSEN---LSETSDAPPAPSSSDKGDTVSNKGSQ----GSGGNTVVTAAVVEGQ-KSGKLKNTLKLNFKFDSMTLVLYS---PNS-EIQLSDSRDESLKLAEFTLGTISTSVHMFSDSSMKASLKLTNCLLDDKRQGVKMITSRMMAMRQDREDSVMVDVSYRQSRDG--TRLDTLVQDLYLCASMEFLLTVADVFLKALSDG--------------------FSGPPKSNKQPASTSKDPAAPAPPVVAKTEMNVVVKNPEIVFVADLTRAEAPALVMTTQCELVMKSEPSGQCMTAAISDLKIVACPFLREKRENNVTTVLQP-CEVFFQSRQSNTEPQCIELSISALTLKVSPIIINTVITIQTALSP--AAETPQELESP--------IPQDLWERRSLRDLKLWFLEEEGE-EVSTSVTRLIPQG------ESLKMSIASICLTLEAGVGHRTVPMLLAKASFQGDVKDWSTLINLHCHLSMEVNYYNEMMGLWEPLLEPLDDEDKDGFRPWTLALKMKKKP--VVSSGVSDEVDGAVPDYKTVISFTSKDQLNVTLSKCGLHMLSNLGTAFAEAAKQTAECFQTDQTPFVVKNRLGLAVSVLHSEVFRPIGKESKDRVVELPDGESLNLDYTLTAESS-----------------DQFSAMTSLSAKN-YIQPTPVGHTTASVIPLIKTGRGMYSVMHNESRVTRFFVCQIYTVEG-SKYVKIRSPFQIINHFSVPFRVYEG----------SVFLGESLPTEEFCVPLGSYRAELSLQPVPDGGEEYEHSESFTYTEVVQKPGKCLEKNCHLRGDSAQILKVNMVPLADTVTSHS--SEEEFDKPIVLHLWPTVLLRNLLPYPITFKLKG-IGDSPSVSLKEGHSSQIHT--------------------------------AIMDFSVLDLRLLGYLQQDWESQYSLSSEQDEISFIKFRSLAREEETESRPELDIAMHVKKEEGQVVLAVHSPYWMVNKTSRLLQYKADD-------IHRKHPKDYDMPLLFSFKPRNFLQNNKIRLMISESELSDDFSIDTVGSYGDVKCKGRQKDYLVGVKIDAS----SFSLTRLVTFLPFYMLVNRTKHVIRVCEEG--QENWTEARPGQAAVPFWPERDSKKLRVKVEGSQSSPRAFDFHQPENCLLLHLDKSLGGIIVDVNLTEHSAVILFSDYHDGAAPFLLINHTKDETLQYHQSNSKRKPSTWFQDEILDLSMRDETDSLCSQAEIDELSPGQAVYYTWAEPTGSRILSWKLGKYKGELKSEEDQLLDVDK-EGKLFLVSFYEGLQRVALFTSEQRIFKKICDSEKIELAQQEISILLQNMGISLVNNNSSQEVAFIGITSSDVVWETKPKKRSRWKVLSVKEAAVLEQHYRDYMENGPV-DSTIIDLDNDYQVLFAANGVDMRIMQPYDAPLRRNFLPALKVEYSVSARQKTYRVQINRIQIQNQLQGAIFPFVFYPIKPPKSVSMDSEPKPLADVSIITRAAGHSDILRIKYFMVLIQEMDLRLDLGFLYAILELFTAEHTSAVTSEQEVELFDKDIEYLKTELNHVSATD--TSPISLYEYFHISPIKLHLSLSLSSGGEDSNKQERETELIPVQSLHLLLKSIGATLTDAQDVLFKLGFFELRYQFRTTQQLQWEVVRHYSKQAIKQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPYQGAIQG--PEEFMEGMALGVKALVGGAVGGLAGAASRITGAMAKGVAAMTMDEEYQQKRREAMNKQPSGLREGLTRGGKGLVSGFVSGITGIVTKPIKGAQKEGAAGFFKGMGKGLVGALTRPTGGIIDMASSTFQGIKRAAELSQDVESLRP--PRFIHEDGVIRPYREREGLGSQMLQSIENGRFAKYRYFAH--AKVNESDFLMITKRGIFFVTKG-TFGQLTCEWQYLFDEFTKAPMIVEGRRLRIEAKER-VKSVFHAKEFGKIINFKTPELAKWVLAKLEDARENLPK------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z713-1", "uniprot_id": "VPS13_DROME", "id": "A1Z713-1", "name": "Intermembrane lipid transfer protein Vps13", "aln": "MVFEAVVADVLNKVLGDYIENLDRNQLKIGIWGGDVVLQNLKIRENALDELDLPVQLIYGYLGKLVLKIPWKNLYSQPVIVNIEDLYVLVSPNNNVQYNAEKEAKYEMDLKKAALDALEAARKKELEMDQPK--------ADAG--FAEKLTAQIVNNLQVQITNVHLRYEDTT-TTG-SPFSFGISLHELELYTTDCDWEKCYMAQQASQVFKIANLSCLSAYLNCGGQLYANNKS-----DLSQQFKTN--IACKETKPNYNYVLGPISCNAKLKLNMNPELDDPPFEKPKIDLTLEMEKLNVGLTNTQFDNLMKLGDAMNRQQLGIPYRKYRPYNIPYKGHARDWWHFAITSILEEEVRKPRESWTWGHIKTHRERCNTYAQKYKEQCLSKKPSAVLTETCRLLETELDVFNLLLIRQRVNIEIAKQ-----REAVPEQKS---GWFSGWGWGGGAKKDD---------QTTSQKLVEKFEAAMTSEEKEKMYRAIGYQENAKPT---DLPESYEAIRMNFKLIALEVGLYKDERNSSAATKDFHELPSLVLLNFSMATALITQRPAAEAISIIAGMREIKVTGLTRNDYTPLLVESKITD---------------EFNLLEVFFETNPLDKLCDQRVKVVARPLQITYDAPTILALINAFQTP--GDVTLSKFEDAASTKISNFKERSATGMQYMIDKKAVLDVDILLMPNILVVPHKGVYDAGNVSLLVVSMGQVHLSSQPRRES-NKLQHLFSAGEDKDEILKTVMENAYDRFTVAVDDVQMLVV-RAGEPWQNALAEANSTEMHVLRPVSLKVTAALCVVDNDPRLPNIKVDIDLPAILVNVSEDRIFLAIKVATSIPLPEQKEPASRLTQTNSRSSMSISNFINKEVKKIGPSASGSSASKDPLLDEIIQYTSLDVNFSLGEINFVLFQSSRKCETSP-DVSIEFLTPDGDVLPSQLTENIQEPIEELPPTPPQQILSIDIRRLEAHFVSKTYESVATVKLGDINLRQYDCQDSDMDVLDVIYTP--KQENSSNYLFTVSCTIADKSSPEFSTKYNSTEQLVVANFEVLQIVLHQECLQRIMEVVNNFQRNLDLVLSSTRPRDRMGSIGGGDGIKRTLNVILEDTEEIMTTDQMKRRKKTRRTHVVETVKVRVIANLDQVGLVLTGRKRPIAEMNVKKFVSSLIIKSSYTEVNIGLKDIQVLDLNPYTIHKNILSIVGKDAFNCQIVIYNKEET----QDYNSDDMKITVDIGCMKIIFLNWFVAGVMNFLNNFTAAQATISQAGAAAAESARQKAMDAYETATRMKLNIRIKAPIIIVPIGSQDRNALLLDLGLLELTNNTVEVAVAEEER-LAVIDEIKLQICDVKISKIVLLDGNESTVDEVDAEVGFLSKFNMMNPMSCTLSITRNLSYTWYRDVPELNLSGRLKSIELTLFADDYALVMLVLNRN---LNEGLEEFPPSEEAPQEAQVRPERRN-------SRAGRLSRTVQVSPIREKIHESIKFNFQFDGVVINLMEGEGAGLARFGIYFLSVKGTKLDNGTLSTSVVLCNIQMDDMRSNSKSQIRQYLSRKDWVQPKLDTDEIIDACYNERNFMVDVTAIIKEDD--TFAEVRVRGFDLIVCIDFLLKLTTFLTLPPEENPRESVYIKPAPVSETARDTKHSIRSSAILAAQELVPVESSSHEVPNRKMNLILHIDEPDIILVENLEDLNTSCIIFNAQVHLNYRSINDKQIVNGQIDALKMYMCAFLPERREMTRHYILHP-CVISLQGSTPEEEGMHISLKLSDIIINVSPATIELLNKAMLSVSSGTMTKCAIAEESR--------NYSNLWHQHHFHSRTYWFTKVEQGVDALEAEQRSVSTDNEKQKTEKCVIEIPSITLVIESGVGYYTKPLISLDTRITAVFNNWSRSLTAHGSLTLNMNYYNQALAEWEPIIELNEVIGRNGVREYTPWELKFEMG----MEKVQSELEDDAEQQAMHMNIHSAETLEITLSKTCLGLLSELAEAFSQAIDQNGLTKPDIVAPYVLENDTGFDVNLNLRKGIFTLHEVHRGGTPVGANSTLLMVAQSEEVDPSVIKTCTISTGGRAYLQTKDLSTLSEEDSEDYTLYVTIGDINKEIALPVSKSDTRFFNLMRSTSHEPWGIISEVKQEYG-TTKVNIHGVVSVHNHFTTGLNIYRRNPAPTAQCFEDIFVGRVRPGEVFHVPLHAIYAESKDLFFS-MRGYRRSVQGISWASNPSDLNYSHQLHCDPTN-TFEPLIMNARRSKSEVYFENTNKYTLLSAFYTIHLRPPLYLRNSLPINIQVSVAG-CSVRKEDGLDAQSSQRFVDRGYRKEDFLDYGEKPVNSGDVLHLPTVRLASKGKESKSFLVVRLVQYLEKDWSCATEIWDYTDDVITWTFSSYDSEMKVD----MDLYVKTENRHGSLMLTLFSPFWMINKTGMMLTYKSETT----SVEVLYHPPEYSGPILFTFRDKLFFDKKKASIRIDNGQWSEKIPLDVAGSVGEVICFANNQKYPVGVHNHLT----QNSLTKQITFIPFYIVCNKCHFDIELQEQSRPADPWLHLE-PNEMEPLWPRNDTKNNLVVRVDGKITP-AFDFTEVICTLLKLEDSKYGGINVDVQTTEGGVYITFTDYKPADAPGLLINHTGKQIVYHEKG-------------------TKNEHILN---------AKSTIMYAWDDPTGPKMLVFGTNKEETDLK-RDGIGEVIMQDGGKVLWVSFLDGLQRVLLFTENESIANRTESTASLQSITQSIDLRIHGIGLSVINNETGLDILYLGVTSSGIIWESKKVTKNRFKELTINENALLEIEYQKYLVHKSVNDVQTYKLDNKFPIDFD----LMILKKTVERNLRRSFYPAIWLSRKSSPFQSQLHVKINRIQVDNQFLDPIFPVVLAPIPPPKSVASTTSLKPFIECSMVQRIMPNSTVRQFKYARILIQEFLFKVDLNFLTAIAEMFA----KEVSDEAAAKQFRQDVESIELPLSAFFEEHSLEEQKSFYDNLHLGPLKIHVSFSMAGSDTKALPG----------FLGSLVQGVGVTLTDVNDVVFRLAFFEREYQFFSQKQLINEITSHYTGQALKQLYVLVLGLDVLGNPYGLVVGLKKGVEDLFYEPFQGAIQG--PGEFAEGLVLGVKSLFGHTVGGAAGAVSKITGAMGKGLAALTFDEDYQKKRRQGIQNKPKNFHEGLARSSKGLVMGFVDGVTGVVTKPVTGARDNGVEGFFKGLGKGAIGLVARPTAGVVDFASGSFEAVKRAADASEDVKRMRP--PRFQHYDFVLRPYCLMEATGNKIMKETDKGKFATTDNFIHCEEIIQKSEYLVVTNYRVMYVQRNEMFGVWTSLWSYLWNEISSVAATARGVQFTVKTDGKKVLGLFSSKESPRKLVLVADERKRDALVDIIESQRSDPNPLRATIAYPAHN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07878-1", "uniprot_id": "VPS13_YEAST", "id": "Q07878-1", "name": "Intermembrane lipid transfer protein VPS13", "aln": "-MLESLAANLLNRLLGSYVENFDPNQLNVGIWSGDVKLKNLKLRKDCLDSLNLPIDVKSGILGDLVLTVPWSSLKNKPVKIIIEDCYLLCSPRSEDHENDEEMIKRAFRLKMRKVSEWELTNQARILSTQSENKTSSSSSEKNNAGFMQSLTTKIIDNLQVTIKNIHLRYEDMDGIFTTGPSSVGLTLNELSAVSTDSNWAPSFIDITQNITHKLLTLNSLCLYWNTDSPPLISDDDQDRSLENFVRGFKDMIASKNSTAPKHQYILKPVSGLGKLSINKLGSTE----EQPHIDLQMFYDEFGLELDDTEYNDILHVLSSIQLRQITKKFKKARPS-FAVSENPTEWFKYIAACVIN-EIHEKNKMWTWESMKEKCEQRRLYTKLWVEKLKLKNLEAPLRDPIQEAQLSELHKDLTYDEIILFRSVAKRQYAQYKLGMTEDSPTPTASSNIEPQTSNKSATKNNGSWLSSWWNGKPTEEVDEDLIMTEEQRQELYDAIEFDENEDKGPVLQVPRERVELRVTSLLKKGSFTIRKK-----------KQNLNLGSIIFENCKVDFAQRPDSFLSSFQLNKFSLEDGSPNALYKHIISVRNSSKDQSSIDNHATGEEEEEDEPLLRASFELNPLDGLADSNLNIKLLGMTVFYHVHFITEVHKFFKASNQHMETIGNIVNAAEATVEGWTTQTRMGIESLLEDHKTVNVSLDLQAPLIILPLDPHDWD--TPCAIIDAGHMSILSDLVPKEKIKEIKELSPEEYDKIDGNEINRLMFDRFQILSQDTQIFVGPDIQSTIGKINTASSTNDFRILDKMKLELTVDLSILPKAYKLPTIRVFGHLPRLSLSINDIQYKTIMNLIANS-IPSMIDDEENNGDYVNYSSGSEKEMKKQIQLQLKNTLKALENMQPLQIEQKFLELHFDIDQAKIAFFQCIKNDSRNSEK---------------------------------------LVDILCQRLNFNFDKRAKEMNLDLRVHSLDVEDYIELTDNKEFKNLISSGVEKVTRSQKDLFTLKYKRVQRIVPHNDTLIELFDQDIVMHMSELQLVLTPRSVLTLMNYAMLTFT------DPNAPEMPADVLRHNKE-----------------------------DRDDAPQKINMKIKMEAVNVIFNDDSIKLATLVLSAGEFTMVLLPERYNINLKLGGLELTDETNESFSRDSVFRKIIQMKGQELVELS-YESFDPATNTKDYDSFLKYSTGSMHVNFIESAVNRMVNFFAKFQKSKVSFDRARLAAYNQAPS-----IDAVNNMKMDIVIKAPIIQFPKLVGTQENNYDTMRFYLG--EFFIENKFSVIDESHKINHIKLGVREGQLSSNLNFDG---------------SSQQLYLVENIGLLFNIDRDPLPQDDTPELKVTSNFESFALDLTENQLTYLLEISNKVSSAFNITDENSGESGGKGEIKSPSPDPASLSSESERTATPQSLQGSNKSNIKNPEQKYLDFSFKAPKIALTLYN--------KTKGVTSLNDCGLTRIMFQDIGCSLGLKNDGTVDGQAHVAAFRIEDVRNIKDNKHTELIPKSKNKEYQFVANISRKNLEVGRLLNISMTMDSPKMILAMDYLVSLKEFFDAIMSKSHENN----------------LYYPENTNQKPENKAIVESVQEGGDVTKIQYSVNIIETALILLADPCDMNSEAISFKIGQFLVT----DQNIMTVAANNVGIFLFKMNSSEEKLRLLDDFSSSLTIDKRNSTPQTLMTNIQLSVQPLLMRISLRDIRLAMLIFKRVTTLLNKMTEKEDNGEEEESTDKIQFSHEFERKLAVLDPSILGERSRASQSSDSESIEVPTAILKN--ETFNADLGGLRFILIGDVHEMPILDMNVN-EITASAKDWSTDFEALASLETYVNIFNYSRSSWEPLLEMIPIT-------------------------FHLSKGHSEMDPAFSFDILTQRIAEITLSARSIAMLSHIPASLTEELPLASRVSQ---KPYQLVNDTELDFDVWIQDKTTEDN---KNEVVLLKANTSLPWEFEDWRSIR-------------------EKLDIDKSKNILGVCVSGQNYKTIMNIDATTEGENLHVLSPPRNNVHNRIVCEARCDENNVKIITFRSTLVIENTTSTEIELLVDSKDPN----KPSLKYAIKPHQSKSVPVEYAYDSDIRIRPASEDIYDWSQQTLSWKSLLSN---QMSIFCSSKEDSNQRFHFEIGAKYD-----EREPLAKIFPHMKIVVSASMTIENLLPADINFSIFDKREEKRTDFLKTGESMEVHH---------------------------------ISLDSFLLMSVQPLQDEASASKPSIVNTPHKSPLNPEDSLSLTLSGGQNLLLKLDYKNIDGTRSKVIRIYSPYIIMNSTDRELYIQSSLLNIAQSKILLENEKRYTIPKMFSFD-KEDDKSNRARIRFKESEWSSKLSFDAIGQSFDASVRIKNKEQESNLGINISEGKGKYLLSKVIEIAPRYIISNTLDIPIEVCETGSMDVQQIESNITKPLYRMRNIVDKQLVLKFLGGDSNWSQPFFIKNVGVTYLKVLKNSRHKLLKIEILLDKATIFIRIKDGGDRWPFSIRNFSDHDFIFYQRD-------------------------------------PRKVSDPYKDDQSNESSSRSFKPIFYRIPSKSIMPYAWDFPTAKEKYLVLESGTR------TREVRLAEIGELPPLRLDKRSKDKPAPIVGLHVVADDDMQALVIVNYKANVGLYKLKTASATTTSSVSVNSSVTDGFVQKDEDEKVNT------------QIVVSFKGVGISLINGRLQELLYINMRGIELRYNESKAYQTFSWKMKWMQIDNQLFSGNYSNILYPTEIP-YTEKEIENHPVISGSISKVNDSLQAVPYFKHVTLLIQEFSIQLDEDMLYAMMDFIK---FPGSPWIMDSRDYKYDEEIQLPDVSELKTAG-----DIYFEIFHIQPTVLHLSFIRS---DEISPGLAEETEESFSSSLYYVHMFAMTLGNINEAPVKVNSLFMDNVRVPLPILMDHIERHYTTQFVYQIHKILGSADCFGNPVGLFNTISSGVWDLFYEPYQGYMMNDRPQEIGIHLAKGGLSFAKKTVFGLSDSMSKFTGSMAKGLS-VTQDLEFQRVRR-LQQRINKNNRNALANSAQSFASTLGSGLSGIALDPYKAMQKEGAAGFLKGLGKGIVGLPTKTAIGFLDLTSNLSQGVKSTTTVLDMQKGCRVRLPRYVDHDQIIKPYDLREAQGQYWLKTVNGGVFMNDEYLSH--VILPGKELAVIVS---MQHIAEVQMATQELMWSTGYPSIQGITLERSGLQIKLKSQSE------------YFIPISDPEERRSLYRNIAIAVREYNKYCEAIL------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*::..::**:.**.*: ::* .**.:*** * . *:** ::::.* .*::*..: * :* * * :**..* .:.* ::: ::* * : : : : : :. * :.: : . * :.*.::::.**** *..:*:**** * *.*::*:::. ::* * . . *: *. * * * . . : .. . :.::: *:* .** :* . : . *:::* : . : : .:: .::.: ::: ::* :* . :. :*: : ::: :: *:* :: : : . * : : :: *: : . : :: . . * : .: . . . . . :* :: :* ** :.*. : . ::. * .. : :. :: .: : . .. ..*** : .: .:. . : *:. ** ***: .. : : : *.. : : * .. : :: .: .:. : :: *: ::: : .::: : : . :::* ::. *:. : *. :. : : :* * : . *:: . . ::* : .:: .:: ::*.::: .** : : :.: : : : . *. . .: : : : :: :. :: : * . : : : .: :. .. . :: : .: : *:*:. .:: *. .: : * : ::. *:: * ..: :: . .:.: .:. : :.: . . :: : :. : : :: * .: : * :. :. : : . .:: : * : *.:.: *: : :: *: :* : :: .. * * ..: ::: ****:: .* .: : : :: : : : . :: :. . :: . : . : . * :::...::.: : * :: : :: : : . : : : :...*: : : * . . * . : : *. . :. . : : . : ::. . . . : .:::* .: .: .: . . * : : : :. :::: : :: .: :. : . :. . . : : ..: : . : : *.:.:. : :.:* *. : . . :.:: : : . : . :. * : .: : : ..: . : . : . ::* : * :: :* . ***::* : :.: : ::*** : :*..: :::: . *: : * : ..: . * . . . . : : : . . : . . :. : . ::.: . . :.::. . : * : : : : * : :*: : : : . . . * : : : .: . . : : ..: :.* ** : : . *. * .. : * : : :. . : .. . . :.: : . :: ..**: ::*.*. * ::. : * * :*:* . ..:: : . :.: *..:.:*. *. : . .: . : . ::: : : * *:: * * : * . : : .. .. . : : : * ... : : .. : . . : *.: : : :.:. : .: : . . : .. . : : .* : . . . :*: :: : : :. .:. ::: * . . :::: :. : . : : : : .: : . * . :: :*::**: . :. :: * * . :*. . *: . : :*: :****: : :* .:: *: ::. . . : * * . :: :*: * :*:*. : . :: .. ** : ::. .:: : . * .: **: * : *:: :: . * :*** **. :..** :****:** : . * *: :. * :: :* * :.: *::*.:*.**:: :* * ::*: ** :. . ::.::...:.:. : .*::*:. .* .. :. *. **:**:*** :* ::.: *.:*::*. :.:* :: : * **: . * :::** :. *. :: : * * . : * : .: ::. : :. *. : .: . * :: :::. . : : * : .: : . ", "identical_positions": 262, "similar_positions": 957, "identity": "7.53%" }, { "cls_id": "homologset.agr.MGI:2444306", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BXR5-1", "uniprot_id": "NALCN_MOUSE", "id": "Q8BXR5-1", "name": "Sodium leak channel NALCN", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKRKQSSR---VEAQPVTDFGPDESLSDNADILWIN---KPWVHSLLRICAIISVISVCMNTPMTFEHYPP---------------------LQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVS----------------------------------LVLQVFEIADIVDQMSPWG-------------MLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFG-TFTYHCVVNDTK-----------------PGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEASSQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGTRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASN--YYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFC-------FVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVG-HMWAPLVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDT----CCLFRILPSTSSSSCDNPKKPTAEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQER-----RSLRHGSNSQRISRGKSLETLTQDHSNTVRYRN----AQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDP-----VTGAVKNTKYHQLYDLLGLVTYLDWVMITVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVV-RELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGP----------IHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHP---FFKRTIALLVLAQSVLLSVKWDVDDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRN--RYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTE-EDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAK--QQQSCSIIHSLRESQEQERSR--------------------------FLNPPSIETTQPSEDSNANSQD-------------------------------------------------------------HSMQPETSS-QQQLLSPTLSD----------------------------------------RGG---SRQDAADTGKPQRKIGQWRLPSAPKPISHSVSS------------------------VNLRFGGRTTMKTVVCKMN-------PMPDTASCGSEVKKWWTRQLTVESDESGDDLLDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6Q760-1", "uniprot_id": "NALCN_RAT", "id": "Q6Q760-1", "name": "Sodium leak channel NALCN", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKRKQSSR---VEAQPVTDFGPDESLSDNADILWIN---KPWVHSLLRICAIISVIPVCMNTPMTFEHYPP---------------------LQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVS----------------------------------LVLQVFEIADIVDQMSPWG-------------MLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFG-TFTYHCVVNDTK-----------------PGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEASSQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGTRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASN--YYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFC-------FVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVG-HMWAPLVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDT----CCLFRILPSTSSSSCDNPKRPTVEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPTKERSILSVQHHIRQER-----RSLRHGSNSQRISRGKSLETLTQDHSNTVRYRN----AQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDP-----VTGAVKNTKYHQLYDLLGLVTYLDWVMITVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVV-RELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGP----------IHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHP---FFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRN--RYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTE-EDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAK--QQQSCSIIHSLRESQQQELSR--------------------------FLNPPSIETTQPSEDTNANSQD-------------------------------------------------------------HNTQPESSS-QQQLLSPTLSD----------------------------------------RGG---SRQDAADTGKPQRKIGQWRLPSAPKPISHSVSS------------------------VNLRFGGRTTMKSVVCKMN-------PMPDTASCGSEVKKWWTRQLTVESDESGDDLLDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IZF0-1", "uniprot_id": "NALCN_HUMAN", "id": "Q8IZF0-1", "name": "Sodium leak channel NALCN", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKRKQSSR---VEAQPVTDFGPDESLSDNADILWIN---KPWVHSLLRICAIISVISVCMNTPMTFEHYPP---------------------LQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVS----------------------------------LVLQVFEIADIVDQMSPWG-------------MLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFG-TFTYHCVVNDTK-----------------PGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASN--YYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFC-------FVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVG-HMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDT----CCLLRSLPTTSSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQER-----RSLRHGSNSQRISRGKSLETLTQDHSNTVRYRN----AQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDP-----VTGAVKNTKYHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVV-RELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGP----------IHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHP---FFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRN--RYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTE-EDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAK--QQQSCSIIHSLRESQQQELSR--------------------------FLNPPSIETTQPSEDTNANSQD-------------------------------------------------------------NSMQPETSS-QQQLLSPTLSD----------------------------------------RGG---SRQDAADAGKPQRKFGQWRLPSAPKPISHSVSS------------------------VNLRFGGRTTMKSVVCKMN-------PMTDAASCGSEVKKWWTRQLTVESDESGDDLLDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BF56-1", "uniprot_id": "A0A8M2BF56_DANRE", "id": "A0A8M2BF56-1", "name": "Sodium leak channel NALCN", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCSAGAISALLFPLIHSLYSTASPSMLKRKQSSR---VEAQPMTDFGPDETLTDSADILWIN---KPWVHSLLRACAIISVISVCMNTPKTFEHYPP---------------------LQYVTFALDTLLMFLYTAEMIAKMHIRGIIKGENSYVKDRWCMFDGFMVVFLWVS----------------------------------LVLQVFEIAELVDQMSPWG-------------MLRIPRALIMIRVFRIYFRFELPRSRITNILKRSGEQIWSVTIFLLFFLLLYGILGVQMFG-TFNHHCVTNETE-----------------KEKVTWNSLAIPDTHCSPN-GEGYQCPVGFKCVDLEDYGLSRQELGYSGFNELGTSIFTVYEAASQEGWVFIMYRAIDSFPRWRSYFYFLTLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDASGGWQLVAVDVNKPHGRAPACLQQLMRSSVFHMFILSMVAVDVIVAASN--YHRG-DHKLTNDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFESLLVVGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFC-------FVEDLDRFTTFPRAFMSMFQILTQEGWVDVMDQTLVAVG-QMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPRIRESFMKQFIDRQQQDP----SCLFRRLPSASSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLMEKEITVNKILRACTRQRMLSGSFEGQPTKERSILSVQHHIRQER-----RSLRHGSTSQRISRGKSLETLTQDHSSTVRYRN----AQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRMIVRARFNASNTDP-----NTGAVNSTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFTRVMHVPTLQIGEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWLPNNVPPESGAQLLMMLRCFRPLRIFKLVPQMRKVV-REVLKGFKEIFLVSILLLTLMLVFATFGVQLFAGKLAKCNDPHISSKDDCHGIFRINVSISKNLNLKLKDGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGP----------IHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPENGGFRAKMYDITQHP---FFKRGIAVLVLAQSVLLSVKWDELGAVTFPLATMSVVFTFIFVLEVTMKLIAMSPAGYWQSRRN--RYDLLVTSLGLIWIILHFALQNAYTYMMGTCVIVFRFFTICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSTAGKAITVLIRIVTGEDWNKIMHDCMVQPPFCTPDKHRYWETDCGNYAGALIYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTE-EDQLLSYNDLRHFQIIWNMVDDKREGVIPTSRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAK--QQQSCSIILSLRESQQQDLRR--------------------------LLNPPSIETTVPSEDTNTHNQD-------------------------------------------------------------NPTQPEQNSGLQTLLSPTLSD----------------------------------------RSG---YRQDSAD--RPQRKLGQWRLP-----------------------------------------AGRTSVKSMVCKMN-------PVTDEASSGSEVKKWWTRQLTVESDESGDDLIDI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JUW5-1", "uniprot_id": "A8JUW5_DROME", "id": "A8JUW5-1", "name": "Sodium leak channel NALCN", "aln": "MIDRLQIRRLGAAARNKRAGGGGGAGGGAVGSGGAGGGGGGGGAGAVPGAAGAAGTGPITGASATAASGSSGSGGHHQHHHHSHPYSTSGINTPATASTSSSSGNSLTPQQQQQQQHPHHQSHHGHHYAHHQQHTHHHAPPHSHHPHPHPHGHPHSYPHLRHSQPASASQFSFNPSPGSSPGNGLGLGARQDAASALNSPTTIVNSGSGSGGGSSVAFGMQPQQQQQSLAGGGGGGSSATAAPSSGGGHNNGAGLGPVVGGGGGGLNLLGGLGGMGGMGGGAAAAGMGICGGISSTVGSAAITGVPPIGLGIATGIGNKIMLGRKQSLK---GGEPFLADYGPEESLNESADIEWVN---KLWVRRLMRLCALVSLTSVSLNTPKTFERYPS---------------------LQFITFASDTAVTLLFTAEMIAKMHIRGVLHGEVPYLKDHWCQFDASMVSFLWIS----------------------------------IILQIFEVLEIVPKFSYLS-------------IMRAPRPLIMIRFLRVFLKFSMPKSRINQIFKRSSQQIYNVTLFFLFFMSLYGLLGVQFFG-ELKNHCVMNNTEY------------DLYKRPILTINSLAIPDTFCSMDPDSGYQCSPGMVCMKMD--FLSSYVIGFNGFEDIATSIFTVYQAASQEGWVFIMYRAIDSLPAWRAAFYFSTMIFFLAWLVKNVFIAVITETFNEIRVQFQQMWGARGHIQKTAASQILSGNDTG-WRLVTIDDNKHGGLAPETCHAILRSPYFRMLVMSVILANGIVTATMTFKHDGRPRDVFYERYYYIELVFTCLLDLETLFKIYCLGWRGYYKHSIHKFELLLAAGTTLHIVPMFYPSGLTYFQVLRVVRLIKASPMLEGFVYKIFGPGKKLGSLIIFTMCLLIISSSISMQLFC-------FLCDFTKFESFPEAFMSMFQILTQEAWVEVMDETMIRTS-KTLTPLVAVYFILYHLFVTLIVLSLFVAVILDNLELDEDIKKLKQLKFREQSAEIKETLPFRLRIFEKFPDSPQMTILHRIPNDFMLPKVRESFMKHFVIELETEDSLVENCKRPMSECWESNVVFRKQKPVRIMNKTAKVRAAGSSLRKLAITHIINDSNNQRLMLGDSAMLPVVGTKGGGGLKSQGTITHSKPWRVDQKKFGSRSIRRSVRSGSIKLKQTYEHLMENGDIAAAPRANSGRARPHDLDIKLLQAKRQQAEMRRNQREEDLRENHPFFDTPLFLVPRESRFRKICQKIVHARYDARLKDP-----LTGKERKVQYKSLHNFLGLVTYLDWVMIFATTLSCISMMFETPNYRVMDHPTLQIAEYGFVIFMSLELALKILADGLFFTPKAYIKDVAAALDVFIYVVSTSFLCWMPLNIPTNSAAQLLMILRCVRPLRIFTLVPHMRKVV-YELCRGFKEILLVSTLLILLMFIFASYGVQLYGGRLARCNDPTISRREDCVGVFMRRVFVTK-MKLTPGPDESYPAMLVPRVWANPRRFNFDNIGDAMLTLFEVLSFKGWLDVRDVLIKAVGP----------VHAVYIHIYIFLGCMIGLTLFVGVVIANYSENKGTALLTVDQRRWCDLKKRLKIAQPLHLPPRPDGRKIRAFTYDITQHI---IFKRVIAVVVLINSMLLSITWIKGEVHTERLVIVSAVLTFVFVVEVVMKNIAFTPRGYWQSRRN--RYDLLVTVAGVIWIILQTILRNDLSYFFGFMVVILRFFTITGKHTTLKMLMLTVGVSVCKSFFIIFGMFLLVFFYALAGTILFGTVKYGEGIGRRANFGSPVTGVAMLFRIVTGEDWNKIMHDCMVQPPYCTLGNN-YWETDCGNFTASLIYFCTFYVIITYIVLNLLVAIIMENFSLFYSNE-EDALLSYADIRNFQNTWNIVDIHQRGVIPVRRVKFILRLLKGRLECDPQKDRLLFKYMCYELDKLHNGEDVTFHDVINMLSYRSVDIRKALQLEELLAREEFEYLVEEEVAKMTIRTWLEGCLKKIRAQNASKQQNSLIAGLRATNEQPVMRPNIQEDKAPLGAVDKSAISTISGAVAGACPPTSDAFSPTFSSTENEEKDGSSSAVVQLPHSETSIAGTGSSATGAATATGTSSGLGVGPPTVQSTARHVMTVGKRGYALNRSDSTGSSAGRKFLAPTSSDPQQRSTLSDKERLHITSQQRKKNSMTTLPHAGQLGQLAKQRGGGGEATKSSSFFAQLNSEIGQFHYPTINAAAAAAALHGYGHGHGHGHGGHGGHGGHGEHQMHHHHGGALGSPSAMMSQMIGGSGKLLPFNNQANAVYEVHDWWQEQVLCP--QTSDDEI--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P50077-1", "uniprot_id": "CCH1_YEAST", "id": "P50077-1", "name": "Calcium-channel protein CCH1", "aln": "-------------MQGRKRTLTEPFEPNTNPFGDNAAVMTENVEDNSETDGNRLESKPQALVPPALNIVPPESSIHSTEEKKGDEYNGNDKDSSLISNIFRTRVGRSSHENLSRPKLSLKTASFGAAESSRRNVSPSTKSAKSSSQYIDLNDERLRRRSFSSYSRSSSRRVSNSPSSTDRPPRSAKVLS-LIAADDMDDFEDLQKGFKSAIDEEGLTWLPQLKSEKSRPVSDVGEDRGEGEQESIPDVHTPNVGASATPGSIHLTPEPAQNGSVSEGLEGSINNSRKKPSPKFFHHLSPQKEDKDQTEVIEYAEDILDFETLQRKLESRPFVLYGHSLGVFSPTNPLRIKIARFLLHRRYSLLYNTLLTFYAILLAIRTYNPHNVVFLYRFSNWTDYFIFILSACFTGNDIAKIIAFGFWDDSEMFKAYGREYKSILQRSGIMKLYIYLREKYGRKLIDFIIPFRIISPGEETKYQRSSLSTSLTKPYGAKENQRPFGTPRAFARSSWNRIDLVSSVSFWLGMFLSIKSYDTKTGIRIFKPLAILRILRLVN-VDTGMPSILRGLKYGIPQLVNVSSMLVYFWIFFGILGVQIFQGSFRRQCVWFNPEDPTDTYQYDMQFCGGYLDPVTKRKQNYIYEDGSEGSVSKGFLCPQYSKCVSNANPYNGR-----ISFDNIVNSMELVFVIMSANTFTDLMYYTMDSD-EMAACLFFIVCIFVLTIWLLNLLIAVLVSSFEIANEEYKKKKFIYGSRKTGYVARIVTG-YWKYFKLKANQTKFPNWSQKGLAIYSHVEFIFVILIICDIGMRASVKVSTSANCNNILLKTDRGISIVLFIESLARLVLYLPNMWKFLTKPSYVYDFIISIITLVISCLAVEGVLGHMYAWLSIFHISRFYRVIISFNLTKKLWKQILSNGVMIWNLSSFYFFFTFLVAIIMAVYFEGVIPPEEMADQPFGMYSLPNSFLSLFIIGSTENWTDILYALQKHSPNISSTFFCSVFFIIWFLLSNSVILNIFIALISESMEVKEEEKRPQQIKHY-----------LKFVYPQKIQEYTHASLVARIR-------------KKFFGGHRNED----------------------------TRDFKQFLMRGTAIMNIAQNMGELADEFKEPPSENLFKKGLSKLTIGVPSLKRLRMFANNPFYKNS------------------------DVVFTETNDINGRT-------------YILELNEYEDEK-----LDYLKKYPLFNYSYYFFSPQHRFRRFCQRLVPPSTGKRTDGSRFFEDSTDLYNKRSYFHHIERDVFVFIFALATILLIVCSCYVTPLYRMHHKMGTWNWSSALDCAFIGAFSIEFIVKTVADGFIYSPNAYLRNPWNFIDFCVLIS--MWINLIAYLKNNGNLSRIFKGLTALRALRCLTISNTARQTFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRLGTCNDGSLG-RADCYNEYSNSVFQWD--------------IMSPRVYQQP-YLHLDSFASAFSSLYQIISLEGWVDLLENMMNSSGIGTPATVMGSAGNALFLVLFNFLSMVFILNLFVSFIVNNQARTTGSAYFTIEEKAWLESQKLLSQAKPKAIPNLIELSRVRQFFYQLAVEKKNFYYASFLQVVLYLHIIMLLSRSYNPGNLIGYQGVYFMFSTSVFLIQEALHMCGEGPRLYFRQKWNSIRLSIIIIAFIMNAVAFHVPASHYWFHNIKGFFLLVIFLFIIPQNDTLTELLETAMASLPPILSLTYTWGVLFLVYAIALNQIFGLTRLGSNTTDNINFRTVIKSMIVLFRCSFGEGWNYIMADLTVSEPYCSSDDN-STYTDCGSETYAYLLLMSWNIISMYIFVNMFVSLIIGNFSYVYRSGGSRSGINRSEIKKYIEAWSKFDTDGTGELELSYLPRIMHSFDGPLSFKIWEGRLTIKSLVENYMEVNPDDPYDVKIDLIGLNKELNTIDKAKIIQRKLQYRRFVQSIHYTNAYNGCIRFSDLLLQIPLYTAYSARECLGIDQYVHHLYILGKVDK-----------------------YLENQRNFDVLEMVVTRWKFHCR----------------------------------------------------------------MKRTIEPEWDVKDPTVSS------------------------------------------------HISNINVNLEPAPGILERE-------------------------------------------PIATPRMDYGVN-------NFMWSPRMNQDSTMEPPEEPIDNNDDSANDLIDR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** . : : :.* :.* . :: . . *: *:: . .* . : . * *: : : * : :: *::: :. : :: :* : . :: ::* ..* :* :.* ::* :*: .. . * . :* . *: .*: ::::* ::*:****:* : :** :.: . :. * : .. . .*: *. *:. . .*::: .*: *: * : :. :** ::** : ::* . **.*: : *::***: .:* . :::: . . .:::. ::* : : : . * ::::. : * .: . : : * * .* : .: *: ::. : :: *:: *. *:* : : :*:. * : .* * : :: : * * : : : ::*.:*:*:* * : * *.::: : . :::**::.*: . ::*.:*:*:* :.:*:.*: *: :*:* ::: :*: : .: : :: *:*. . : .. . : : * . . : * .: : .: : : * : .: : : : :::* *: . ::. : ***.:*: :* . . .. *. .. .* : :* : . * ** : :: . : *: :*:*: :* :***::::*.* ::: :*. : : :: :. . :::: * ..*.** :.: *:.. : *:::*: .. : : *:: *: :*:.:: *:*. *** : : ** . : * . : ***: :* :::*....*: :*::::*::**::: : ::: * :.::: :: **. :: *.***..:: * ...*:* :*:::: * : :. *. *:* :* : .* *::: . : : ::: : ::* . * :*::: .:: . * :::.: * * .::: : : :: : : : .::. *: * :: **. *: *. .*: : : :*.: **:* :** .: *.. . ** : ..: :*:* **.** ** * *. *:*: .. ****. : : : : :: :* **.:*::*::*: *** .* . . :. ::::: *. .* . * : : ::: : * *. . :.:* :* : : .:: . .: : *. . * *: ::. * ..: :. * : . *: . :. * . :. . . ** *. : : . : * . : : : . . : .: ::.:* : ", "identical_positions": 231, "similar_positions": 550, "identity": "9.79%" }, { "cls_id": "homologset.agr.MGI:2444308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGV9-1", "uniprot_id": "ATG4D_MOUSE", "id": "Q8BGV9-1", "name": "Cysteine protease ATG4D", "aln": "MN---------------------------------SVSPAAAQYRSGS-SEDARR----ADCRRPRGQTRIPDPSNLGPSGS------------------------------------GVAALGSSGTDPAEPDEVDK-------FKAKFLTAWNNVKYGWAVKS--RTSFSKISTVHLCGRCYH------------------------------FE------------------------------------------GEGDIQRFQRDFVSRLWLTYRRDFPPLAGGSLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWRWVEGTGLASS--EMPGPASPSRCRGP-------------------------GRRGPPRWTQGALEMEQDRWHRRIVSWFADHP--RAPFGLHRLVELGRSSG-KKAGDWYGPSVVAHILRKAVESCS----EVSRLVVYVSQDCTVYKADVARLLSWPDPTAE-----------------------WKSVVILVPVRLGGETLNPVYVPCVKELLRSELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQPSFPLESFHCTSPRKMAFAKMDPSCTVGFYAGNRKEFETLCSELMRIL--------------------------SSSSVTERYP---------------MFTVAEGHAQDHSLDALCT-QLSQPTLRLPCTGRLLKAKRPS-------------SEDFVFL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R5T6-1", "uniprot_id": "M0R5T6_RAT", "id": "M0R5T6-1", "name": "Cysteine protease", "aln": "MN---------------------------------SVSPAAAQYRSGS-PEDARR----PDCRRPRGQTRIPDPSNLGPSGS------------------------------------GVAALGSTGTDPAEPDEVDK-------FKTKFLTAWNNVKYGWAVKS--RTSFSKISSVHLCGRCYH------------------------------FE------------------------------------------GEGDIQRFQRDFVSRLWLTYRRDFPPLAG-SLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWRWVEGTGLASS--EMPGPASPSRYRGP-------------------------GRRGPLRCAQGALEMEPDRWHRRIVSWFADHP--QAPFGLHRLVELGQSSG-KKAGDWYGPSVVAHILRKAVESCS----EVTRLVVYVSQDCTVYKADVARLVSWPDPTAE-----------------------WKSVVILVPVRLGGETLNPVYVPCVKELLRSELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVNQANFPLESFHCTSPRKMAFAKMDPSCTVGFYAGNRKEFETLCSELMRIL--------------------------SSSSVTERYP---------------MFTVAEGHAQDHSLDALCT-QLSQPTLRLPCTGRLLKAKRPS-------------SEDFVFL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86TL0-1", "uniprot_id": "ATG4D_HUMAN", "id": "Q86TL0-1", "name": "Cysteine protease ATG4D", "aln": "MN---------------------------------SVSPAAAQYRSSS-PEDARRR---PEARRPRG-PRGPDPNGLGPSGA------------------------------------SGPALGSPGAGPSEPDEVDK-------FKAKFLTAWNNVKYGWVVKS--RTSFSKISSIHLCGRRYR------------------------------FE------------------------------------------GEGDIQRFQRDFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGLGPP--ELSGSASPSRYHGP-------------------------ARWMPPRWAQGAPELEQERRHRQIVSWFADHP--RAPFGLHRLVELGQSSG-KKAGDWYGPSLVAHILRKAVESCS----DVTRLVVYVSQDCTVYKADVARLVARPDPTAE-----------------------WKSVVILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVL--------------------------SSSSATERYP---------------MFTLAEGHAQDHSLDDLCS-QLAQPTLRLPRTGRLLRAKRPS-------------SEDFVFL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "R4GER2-1", "uniprot_id": "ATG4D_DANRE", "id": "R4GER2-1", "name": "Cysteine protease atg4da", "aln": "MN---------------------------------SVSPSAVQYIVGGGAHEDKAS---ASSKRHLGHGAVPDGIREG-SG--------------------------------------------------EPDEVDR-------LKAKFMSAWNNVKYGWTVKS--KTSFNKSSPLILLGQSFL------------------------------FN------------------------------------------NEDEVERFRQTFVSCVWLTYRREFPQLDGSSLTTDCGWGCMLRSGQMMLAQGLLLHLMPTDWRWSDCHALTDVDFEVLKPRSPSRPAGMSMPSFSSSWSSSIPQINPSPGITEAHRRAPARCPSASPDPQVDALHRKVVSCFGDHP--SAPFGVHQLVELGKESG-KRAGDWYGPSVVAHMLRKAVARAA----EFEDLAVYVAQDCTVYKEDVMSLCE--SSGVG-----------------------WKSVVILVPVRLGGESLNPSYIECVKNILKLKCCIGIIGGKPKHSLFFVGFQDEQLLYLDPHYCQPVVDVTQANFSLESFHCNSPRKMNFSRMDPSCTIGLYARSKTDFESLCTAVSEAL--------------------------SSS--KEKYP---------------IFTFVEGRGQIYGMEGPSGGSVDAPAHIFTCSRLSRNNKRGS-------------TDEFVLL--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF80-1", "uniprot_id": "Q9VF80_DROME", "id": "Q9VF80-1", "name": "Cysteine protease", "aln": "MNYDGLLSKLTDEKLMLFEAAGEGTIVEGSRICGQDADPLSLPLVEDGAIEEEQAAPIQTIHRTVFAVPRVPSPSPVSTSGANLNLKTENAATATPQRKISTSSRFMNAFSQLYGGGNSGPSCGHVEQHNEEPGDLSANRTPTKGMESKLVAMWHNVKYGWSGKMR-QTSFSKEQPVWLLGRCYHRRFTPPVSMESSITELPSGADTTPDNATSAFDSIQATSTSTSLYPALNPQQIDEIVVPQELGMDAVENQVGEQPWEEGIEGFRRDFYSRIWMTYRREFPIMNGSNYTSDCGWGCMLRSGQMLFAQGLICHFLGRSWRYDSESQLHST--------------------------------------------------------YEDNMHKKIVKWFGDSSSKSSPFSIHALVRLGEHLG-KKPGDWYGPASVSYLLKHALEHAAQENADFDNISVYVAKDCTIYLQDIEDQCSIPEPAPKPHVPWQQAKRPQAETTKTEQQQHWKSLIVLIPLRLGSDKLNPVYAHCLKLLLSTEHCLGILGGKPKHSLYFVGFQEDRLIHLDPHYCQEMVDVNQENFSLHSFHCKSPRKLKASKMDPSCCIGFYCATKSDFDNFMESVQLYLHPMRCASGATVDKAAGSHHTTPQSSHQTEQTEMNYP---------------LFSFSRGRCMDHERDEMSDSLYKPLIKQVASLAQELGAQLAPPQHGDEHDQDDSESEEFVLL--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53867-1", "uniprot_id": "ATG4_YEAST", "id": "P53867-1", "name": "Cysteine protease ATG4", "aln": "MQR------------------------------WLQLWKMDLVQKVSHGVFEGSSEEPAALMNHDYIVLGEVYPERDEESGA----------------------------------------EQCEQDCRYRGEAVSDG-----FLSSLFGREISSYTKEFLLDVQSRVNFTYRTRFVPIARAPD-----------------------------------------------------------------------------GPSPLSLNLLVRTNPISTIEDYIANPDCFNTDIGWGCMIRTGQSLLGNALQILHLGRDFRVNGNESLERE--------------------------------------------------------------SKFVNWFNDTP--EAPFSLHNFVSAGTELSDKRPGEWFGPAATARSIQSLIYGFP--ECGIDDCIVSVSS-GDIYENEVEKVFAENPNSR---------------------------ILFLLGVKLGINAVNESYRESICGILSSTQSVGIAGGRPSSSLYFFGYQGNEFLHFDPHIPQPAVEDS----FVESCHTSKFGKLQLSEMDPSMLIGILIKGEKDWQQWKLEVAESAIINVLAKRMDDFDVSCSMDDVESVSSNSMKKDASNNENLGVLEGDYVDIGAIFPHTTNTEDVDEYDCFQDIHCKKQKIVVMGNTHTVNANLTDYEVEG-----VLVEKETVGIHSPIDEKC", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . . : . . ** . :. :.: : . . : . :..*. . .: . : : : .:* *****:*:** ::.:.* : .: * :.*. * * . :**.:* :* * . *:.*:*:**: .: :: : . . * *:. :* :: ::.*: ::** : :* * .: :* .:** **:* **:*.*:* : ::::*** * *: . :.* * .. *: :.**** :*: ..::: : .: :*. . : . : .: * : ", "identical_positions": 62, "similar_positions": 116, "identity": "8.28%" }, { "cls_id": "homologset.agr.MGI:2444310", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BZ52-1", "uniprot_id": "FSD2_MOUSE", "id": "Q8BZ52-1", "name": "Fibronectin type III and SPRY domain-containing protein 2", "aln": "MEEEAEEESGLGRSAAPKDFHFYHMDLYDSEDRLQLFPGDSSRIRREVTQAE-------------------------------DDRELGDEFVDE--HRLGTLGYPSYGMRRRDPGREPRDWG---EAAEAEDLGYGGGQGPLDQCQDLREAYRYTHGRASEEYECYVIPEEEDEEEPADVFCITCKTPVRTVEKDFDTHKEHEVTPISKALEHAKDEVHKNMCKLEQQIIEMENFASHLEEVFITVEENFGRQEQNFECHYNGILETLAQKYEEKIQALGEKKREKLEALYGQLVSCGENLDACRELMETVEEMCHEEKVEFLKDAVAMTDRLGKFLKTKTDVELSAQPEFEDQTLDFSDVEQLMDAINTIPAPSAPVINPQAPNSATGSSVRVCWSLYSDDTVESYQLSYRPVQDSSSGKDRAEFTMMVKETYCSVTNLEPNTQYEFWVIAQNRTGPSPCSEHAVYMTAPSPPSIKTEAIRSCEEAVLICWESGNLNPVDSYTVELIQAETPEASGVTESVVGIPTCESLIQLQPRHSYTIYVRALNVGGTSARSEPATVHTTGSYFQLNKDTCHPWLTISEDGFTVVRSEKK-SFRKELPPSKTQFTRCVAVMGNLIPVRGRHYWEVEVAEHLDYTVGVACEDVPKQEDLGANSLSWCMRHTFVSKRHRYEFLHNKMTPDIRITVAPRKIGVLLDYENAKLSFFNVDIAQHLYTFSCQLHQFVHPCFSLEKSGCLKICNGISMPKHVTFF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ADN6-1", "uniprot_id": "D4ADN6_RAT", "id": "D4ADN6-1", "name": "", "aln": "MEEEAGEEPGLGRSTAPRDFHFYHMDLYDSEDRLQLFPGESSRTRREVTQAELTNEPRGAGD---SKNLQKEVDALVHLYGLEDEHELGGEFVDE--HRLGTLGYP-YGMRRRDPGREQRDWGLSGEAAEAEDLCYG-VQGPPDQCQDLREAYRYTHGRASEEYECYVIPEEEDEEEPADVFCVTCKTPVRTVEKDFDIHKEHEVTPINKALEHAKDEIHKNMCKLEQQIIEMENFASHLEEVFITVEENFGRQEQNFECHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLVSCGENLDACRELMETIEEMCHEEKVDFLKDAVAMTDRLGKFLKTKTDVELSAKPEFEDQTLDFSDVEQLMDSINTVPAPSAPVINPQAPNSATGSSVRVCWSLYSDDTVESYQLSYRPVQDSSPGKDQAEFTMTVKETYCSVKNLEPNTQYEFWVIAQNRTGPSPSSEHVVYMTAPSPPSIKTEAIRSCEEAVLICWESGNLNPVDSYTVELIQAETPEASGVTESVVGIPTCESLIQLQPRHSYTIYVRALNVGGTSARSKPATVHTTGSYFQLNKDTCHPWLTISEDGFTVVRSEKKRSFRRELPPSKAQFSRCVAVMGNLIPVRGRHYWEVEVDEHLDYTVGVACEDVPKQEDLGANRLSWCMRHTFASTRHRYEFLHNGTTPDIRITVAPKKIGVLLDYEDSKLSFFNVDIAQHLYTFSCPLHQFVHPCFSLEKSGGLKICNGISAPKHVTFF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1L4K1-1", "uniprot_id": "FSD2_HUMAN", "id": "A1L4K1-1", "name": "Fibronectin type III and SPRY domain-containing protein 2", "aln": "MEEESGEELGLDRS-TPKDFHFYHMDLYDSEDRLHLFPEENTRMR-KVVQAEMANESRGAGDGKAQRDLQEEVDELVHLYGLEDDHELGDEFVDENIPRTGVSEYPPYMMKRRDPAREQRDWRLSGEAAEAEDLGFG-GWGSAGQCQDLREAYRYTHGRASEEYECYVIPEEEDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIEMENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLVSCGENLDTCKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVEISAQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQLSYRPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSERAVYMTAPSPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELTQAESPEASGVTESVVGIPTCESVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPWLTISEDGLTAVRSERR-TPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRVGVAFADVRKQEDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHVTFY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****: ** **.** :*:****************:*** :.:* * :*.*** *::***.***** * *. ** * *:****.** *** ******** :* *. .*********************************.*****:*****:*:.:* ** ****** *:.:*** ****:**** ***:*********.**************:******.*** ********************:******************:*:*****:*********:*:******:**************:**:*****************.:***:***********.***********************************.*.*:****: ********.** ********* *:**:****.**:.********* ***: *************************** ***:******************::**** :** *******:**.*.**:****** ****:****************:*.****:: : :**.**.::*:**************:******* ***** **** ** ******** *********.*.**:****** ********.*:***:*****.:********::******** **:**********.* **: **** ******:", "identical_positions": 576, "similar_positions": 92, "identity": "76.49%" }, { "cls_id": "homologset.agr.MGI:2444314", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R508-1", "uniprot_id": "FAT3_RAT", "id": "Q8R508-1", "name": "Protocadherin Fat 3", "aln": "-------MGVTMRHCIDTRPPS-CLIFLLLKLCATVS----QGLPGTGPLGFH--------FTHALYNATVYENSAARTYVN--SQSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIIKGSVRGED-----LEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPIIHVVTHTPFSLDKEP-TYAVVTVDDLDEGANGEIESVSIVDGDPLEQFFLAK-------------EGKWMNEYKVKERRQVDWESFSYGYNLTIQAKDKGSPQKFSELKTVHIANPRRDSTPIKFEKDVYDISISEFSPPGVMVAIVKVNPEPLD----VEYKLLPGKDAEYFKINPRSGLIVTAQPLNTVKKEVYKLEVSDKEGD-------AKAQVTIGIEDANDHTPEFQETLYETFVNESVPVGTNVLTVSASDKDKGENGYITYSIASLNLLPFAINQFTGVISTTEELDFESSPETYRFIVRASDWGSPYRHESEVNVTIRVGNVNDNSPLFEKVACQGVISYDFPVGGHITAISAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLMNSGIKNGNFALRITATDGENFADPMAINISVLHGKVSSKS--------FSCRETRVAQKLAEKLLIKAKANGKLNQEDGFLDF------YSINRQGPHFDKSFPSDVAVKENMPVGTNILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYVLNITIYDLGKPQKSSWRLLTVNVEDANDNSPVFLQDS-YSVSILESSSIGTEIIQVEARDKDLGSNGEVTYSVLTDTHQFVINSSTGIVYIADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKIFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETQDPDLGLGGQVRYSLVNDYNGR--FEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSISFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTAHDEDSG-RDGEIQYSIRDGSGLGRFNIDDESGVITAADILDRETTASYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSGSNE-KLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGSSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKTGMVSS-RKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSP-IPLTFDEPFYNFT-IMESDKVTEIVGVVSVQP-ANTPLWFDIIG-----------------------GNFDSSFDAEKGVGTIVIAKPLDAEQRSVYNMSVEVTDGTNVAVTQVFITVLDNNDNGPEFSQPHYDVTISEDVPPDTEILQIEATDRDEKHKLSYTIHSSIDAISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSVVLQVTALDKDKGENAELIYSIEAGNTGNTFKIEPVLGIITISKEPDMTAMGQFVLSVKVTDQGSPPMSATAIVRISISMSDNSHPKFTHKDYQAEVNENVDIGTSVILISAISQSTLIYEVKDGNINGVFTINPYSGVITTRRALDYEHTSSYQLIIQATNMAGMASNATVSVQVVDENDNPPVFLFSQYSGSLSEAAPINSLVRSLDNSP---LVIRATDADSNQNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHEVIAHFHFHVHVRDSGNPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETVLLLPTYVGVEVLKVSATDPDSEVPPELTYSLMEG-SVDHFLMDPNTGVLTIKNNNLSKDH----YMLIVRVSDGKFYSTAMVTIMVKEAMDSGLHFTQSFYSTSISENSTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDH-----LRVARVVVRVNIEDVNDNSPVFVGLPYYAAVQVDAEPGTLIYRVTAIDKDKGANGEVTYVLQDDYG-HFEINPNSGNVILKEAFNSDLSNIDYGVTILAKDGGTPSLSTFVELPITIVNKAMPVFDKPFYTASINEDISINTPI-LSINATSPEGQGIIYLIIDGDPFQQFNIDFDTGVLKVISPLDYEVMSVYKLTVRASDALTGARAEVTVDLLVDDVNDNPPVFDQPTYNTTLSESSLIGTPVLQLVSTDADSGNNNLVHYQIVQDT-YNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVTATDNGFPSLSSEVLVQIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVLTLSSHR-KQRMEPLYSLNVSVSDGLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENAASGTKVIHVRATDGDPGTYGQVSYSIINDFAKDRFLIDSN-GQIITTERLDRENPLEGDISIYLRALDGGGRTTFCTVRVIVVDENDNAPQFMTLEYRASVRADVGRGHLVTQVQALDPDDGANSRITYSLYSEAS-VSVADLLEIDPDNGWMVTKGNFNQLRNTVLSFFVKAVDGGIPVRHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTSIGSTIDTLRILPNQS-----VRFSTVNGERPENNKENVFIIEQETGAIKLDKRLDHEVSPAFHFKVAATIPLDKVDIVFTVDVDVKVLDLNDNKPVFETSSYETIIMEGMPVGTKLAQVRAIDTDWGANGQVTYSLHSD--------SHLEKVMEAFNIDSNTGWISTLKDLDHETDPTFSFFVVASDLGEAFSLSSMALVSVKVTDINDNAPVFAHEVYRGNVKESDPPGEVVAVLSTLDKDTSNINRQVSYHITGGNPRGRFALGMVQSEWKVYVKRPLDREEQDIYFLNITASDGLFVTQAMVEVTVSDVNDNSPVCDQVAYSASLPEDIPSNKIILKVSAKDADIGSNGDIRYSLYGSGNSDFFLDPESGELKTLALLDRERVPVYNLIARATDGG--GRFCSSTVLLLLEDVNDNPPVFSSNHYTACVYENTATKALLTRVQAVDPDVGINRKVVYSLEDSASGVFSIDSSSGVIVLEQPLDREQQSSYNISVRATDQSPGQSLSSLTSVTITVLDINDNPPVFERRDYLVTVPEDTSLGTQVLSVFATSKDIGTNAEITYLIRSGNEQGKFRINPKTGGISVLEALDYEMCKRFYLVVEAKDGGTPALSTAATVSIDLTDVNDNPPRFSQDVYSAVISEDALEGDSVILLIAEDVDSKPNGQIRFSIVGGDRDNEFAVDPILGLVKVKKKLDRERVSGYSLLIQAVDSGIPAMSSTTTVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEDEEFMLDSHGILRSAVVFRHMESPEYLLCIQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTFALKS------EQKSLFKVNSHDGKIIALGGLDSGKYVLNVSVSDGRFQVPIDVVVHVEQLVHEMLQNTVTIRFENVSPEDFVGLHMHGFRRILRNAVLTQKQDSLRIISIQPVVGTNQ--------------LDMLFAVEMHSS-----EFYKPAYLIQKLSNARRHLEN--VMHIAAILEKNCSG--LDCQEQHCEQGLSLDSHALMTYSTARISFVCPRFYRNVRCTCNGGV----CPGSNDPCVEKPCPEDMQCVGYEASRRPFLCQCPPGKLG--------ECSG-------HTSLSFAGNSYIKYRLSENSR----EEDFKLALRLRTLQSNGIIMYTR-ANPCMILKIVEGKLWFQLDCGSGPGILGISSRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQTLSTDS-AIFFGALVQADNIRSLTDTRVTQVLGGFQGCLDSVVLNHNELPLQNKR-SSFAEVVGLTELKLGC-----VLYPDACQRSPCLHGGSCSGLPSGGYQCSCLSQFTGTNCESEITACFPNPCRNGGSCDPIG-NTFICSC------------------------------------KAGLTGVTCEDDVDECEREECENGGSCVNLFGSFFCNCTPGYVGQYCG--LRPVVVPNIQAGHSYVGKEELIGIAVVLFVIFTLIVLFIVFRKKVFRKNYSRNNITLVQDPATAALLHKSNGIPFRSLR--AGDGRNVYQE---VGPPQVPVRPMAYTPCFQSD---SRSNLDKGLDALG--GEPQELSTFHP-ESPRIL--TARRGVVVCSVAPNLPAVSPCRSDCDSIRKNGWDTGSENKGAEDTGEVTCFAN----SNKGSNSEVQSLNSFQSDSGDDN--------------------------------AYHWDTSDWMPGAR--LSDIEEMPNYESQDGGAVHQGSTRELESDYYLGGYDIDSEYPPPHEEEFLSQDQ----LPPPLPEDFPEQYEALPPSQPTSLTGTMSPDCRRRPRFHPSQYLPPHPLPGETDLGGPPSSCDFSTFAVSMNQGTEVMAPTDSVSLSLHNSRGTSSSDMSARCGFDDSEVAMSDYESAGELSLTNLHIPFVETQHQTQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BNA6-1", "uniprot_id": "FAT3_MOUSE", "id": "Q8BNA6-1", "name": "Protocadherin Fat 3", "aln": "-------MSVTMGHCMGTKPPS-CIILLLLKLFATVS----QGLPGTGPLGFH--------FTHSTYNATVYENSAARTYVN--SQSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIIKGSVRGED-----LEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPIIHVVSHTPFSLDKEP-TYAVVTVDDLDEGANGEIESLSIVDGDPLEQFFLAK-------------EGKWLNEYKVKERRQVDWESFSYGYNLTIQAKDKGSPQKFSELKTVHIANPRRDNTPVRFEKDVYEVSISEFSPPGVLVAIVKVSPEPLD----VEYKLLPGKDSDYFKINPRSGLIVTAQPLNTVKKEVYKLEVSDKEGD-------AKAQVTIGIEDANDHTPEFQEALYETFVNESVRVGTNVLTVSASDKDKGENGYITYSIASLNLLPFAINQFTGVISTTEELDFESSPETYRFIVRASDWGSPYRHESEVNVTIRVGNVNDNSPLFEKVACQGVISYDFPVGGHITAISAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLMNSGIKNGNFALRITATDGENFADPMAINISVLHGKVSSKS--------FSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDF------YSINRQGPHFDKSFPSDVAVKEDMLVGTNILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYVLNITIYDLGKPQKSSWRLLTVNVEDANDNNPVFLQDS-YSVSILESSSIGTEIIQVEARDKDLGSNGEVMYSVLTDTHQFIINSSTGIVYIADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKIFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETQDPDLGLGGQVRYSLVNDYNGR--FEVDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTAHDEDSG-RDGEIQYSIRDGSGLGRFNIDDESGVITAADSLDRETTASYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSGSNE-KLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGSSPKQSTIWVVVQVLDENDNRPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDKDEGPNAEISYSIVDGNDDGKFFIDPKTGMVSS-RKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSP-IPLTFDEPFYNFT-VMESDKVTEIVGVVSVQP-ANTPLWFDIVG-----------------------GNFDSSFDAEKGVGTIVIAKPLDAEQRSVYNMSVEVTDGTNIAVTQVFIKVLDNNDNGPEFSQPHYDVTISEDVLPDTEILQIEATDRDEKHKLSYTIHSSIDAVSMRKFRMDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSVVLQVTALDKDKGENAELIYSIEAGNTGNTFKIEPVLGIITISKEPDMAAMGQFVLSVKVTDQGSPPMSATAIVRISISMSDNSHPKFTHKDYQAEVNENVDIGTSVILISAISQSTLIYEVKDGNINGVFTINPYSGVITTRRALDYEHTSSYQLIIQATNMAGMASNATISVQIVDENDNPPVFLFSQYSGSLSEAAPINSIVRSLDNSP---LVIRATDADSNQNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHEAIAHFHFHVHVRDSGNPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETVLLLPTYIGVEVLKVSATDPDSEVPPELTYSLMEG-SVDNFLMDPNTGVLTIKNNNLSKDH----YMLIVRVSDGKFYSTAMVTVMVKEAMDSGLHFTQSFYSTSISENSTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDH-----LRVARVVVRVNIEDVNDNSPVFVGLPYYAAVQVDAEPGTLIYRVTAIDKDKGANGEVTYVLQDDYG-HFEINPNSGNVILREAFNSDLSNIDYGVTILAKDGGNPSLSTFVELPITIVNKAMPVFDKPFYTASINEDITMNTPI-LSINATSPEGQGIIYLIIDGDPFQQFNIDFDTGVLKVISPLDYEVTSVYKLTVRASDALTGARAEVTVDLLVDDINDNPPVFDQPTYNTTLSESSLIGTPVLQLVSTDADSGNNKLVRYQIVQDT-YNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVTATDNGFPSLSSEVLVQIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDLDRLEYSILSGNDRASFLMDSKSGVLTLSSHR-KQRMEPLYSLNVSVSDGLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENAASGTKVIHVRATDGDPGTYGQVSYSIINDFAKDRFLIDSN-GQIITTERLDRENPLEGDISIYLRALDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGRGHLVTQVQALDPDDGANSRITYSLYSEAS-VSVADLLEIDPDNGWMVTKGNFNQLRNTVLSFFVKAVDGGIPVRHSLIPVYIHVLPPETFLPSFTQSQYSFTITEDTSIGSTVDTLRILPNQS-----VRFSMVNGERPENNKEGVFIIEQETGAIKLDKRLDHEVSPAFHFKVAATIPLDKVDIVFTVDVDVKVLDLNDNKPVFETSTYETIIMEGMPVGTKLAQVRAIDMDWGANGQVTYSLHSD--------SHLEKVIEAFNIDSNTGWISTLKDLDHETDPAFSFFVVASDLGEAFSLSSMALVSVKVTDINDNAPVFAHEVYRGNVKESDPPGEVVAVLSTLDKDTSNINRQVSYHITGGNPRGQFALGMVQSEWKVYVKRPLDREEQDIYFLNITASDGLFVTQAMVEVTVSDVNDNSPVCDQVAYSASLPEDIPSNKIILKVSAKDADIGSNGDIRYSLYGSGNNEFFLDPESGELKTLAVLDRERVPVYNLIARATDGG--GRFCSSSVLLLLEDVNDNPPVFSSNHYTACVYENTATKALLTRVQAMDPDVGINRKVVYSLEDSASGVFSIDSSSGVIVLEQPLDREQQSSYNISVRATDQSPGQSLSSLASVTITVLDINDNPPVFERRDYLVTVPEDTSLGTQVLSVFATSKDIGTNAEITYLIRSGNEQGKFSINPKTGGISVLEALDYETCRRFYLVVEAKDGGTPALSTAATVSIDLTDVNDNPPRFSQDVYSAVISEDALEGDSVILLIAEDVDSKPNGQIRFSIVGGDRDNEFAVDPILGLVKVKKKLDRERVSGYSLLIQAVDSGIPAMSSTTTVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEDEEFMLDSHGILRSAVVFRHMESPEYLLCIQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTFALKS------EQKSLFKVNSHDGKIIALGGLDSGKYVLNVSVSDGRFQVPIDVVVHVEQLVHEMLQNTVTIRFEDVSPEDFVGLHMHGFRRILRNAVLTQKQDSLRIISIQPVVGTNQ--------------LDMLFAVEMHSS-----EFYKPAYLIQKLSNARRHLEN--VMHIAAILEKNCSG--LDCQEQHCEQGLSLDSHALMTYSTARISFVCPRFYRNVRCTCNGGV----CPGSNDPCVEKPCPEDMQCVGYEASRRPFLCQCPPGKLG--------ECSG-------HTSLSFAGNSYIKYRLSENSK----EEDFKLALRLRTLQSNGIIMYTR-ANPCMILKIVEGKLWFQLDCGSGPGILGISSRAVNDGSWHSVFLELNRNFTSLALDDSYVERRRAPLYFQTLSTDS-AIFFGALVQADNVRSLTDTRVTQVLGGFQGCLDSVVLNHYELPLQNKR-SSFAEVVGLTELKLGC-----VLYPDACQRSPCLHGGSCSSLPSGGYQCSCLSQFTGTNCESEITACFPNPCRNGGSCDPIG-NTFVCSC------------------------------------KAGLTGVTCEDDVDECEREECENGGSCVNLFGSFFCNCTPGYVGQYCG--LRPVVVPNIQAGHSYVGKEELIGIAVVLFVIFTLIVLFIVFRKKVFRKNYSRNNITLVQDPATAALLHKSNGIPFRSLR--AGDGRNVYQE---VGPPQVPVRPMAYTPCFQSD---SRSNLDKGLDVLG--GEPQEMSTFHP-ESPRIL--TARRGVVVCSVAPNLPAVSPCRSDCDSIRKNGWDTGSENKGTEDTGEVTCFTN----SNKGSNSEVQSLSSFQSDSGDDN--------------------------------AYHWDTSDWMPGAR--LSDIEEMPNYESQDGGAAHQGSTRELESDYYLGGYDIDSEYPPPHEEEFLSRDQ----LPPPLPEDFPDQYEALPPSQPTSLTSTMSPDCRRRPRFHPSQYLPPHPLPGETDLGGPSSSCDFSTFAVNMNQGTEVMAPTDSVSLSLHNSRGTSSSEMSARCGFDDSEVAMSDYESAGELSLTNLHIPFVETQQQTQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDW7-3", "uniprot_id": "FAT3_HUMAN", "id": "Q8TDW7-3", "name": "Protocadherin Fat 3", "aln": "-------MDIIMGHCVGTRPPACCLILLLFKLLATVS----QGLPGTGPLGFH--------FTHSIYNATVYENSAARTYVN--SQSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIVKGSVRGED-----LEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTIHVVTHVPFSLEKEP-TYAVVTVDDLDDGANGEIESVSIVAGDPLDQFFLAK-------------EGKWLNEYKIKERKQIDWESFPYGYNLTLQAKDKGSPQKCSALKAVYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKLSPEPID----VEYKLSPGEDAVYFKINPRSGLIVTARPLNTVKKEVYKLEVTNKEGD-------LKAQVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIASLNLLPFVINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIRIGNVNDNSPLFEKVACQGVISYDFPVGGHITAVSAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLTNSGIKNGNFALRITATDGENLADPMSINISVLHGKVSSKS--------FSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDF------YSINRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQDS-YSVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLTDTQQFAINSSTGIVYVADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDYNGR--FEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSG-RDGEIQYSIRDGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNE-KLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKTGMVSS-RKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSP-IPLTFDEPFYNFT-VMESDRVTEIVGVVSVQP-ANTPLWFDIVG-----------------------GNFDSAFDAEKGVGTIVIAKPLDAEQRSIYNMSVEVTDGTNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQIEATDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITICKEPDMTTMGQFVLSIKVTDQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISAISQSTLIYEVKDGDINGIFTINPYSGVITTQKALDYERTSSYQLIIQATNMAGMASNATVNIQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSP---LVIRATDADSNRNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETILLLPTYVGVEVLKVSATDPDSEVPPELTYSLMEG-SLDHFLIDSNSGVLTIKNNNLSKDH----YMLIVKVSDGKFYSTSMVTIMVKEAMDSGLHFTQSFYSTSISENNTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDH-----LRVARVVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQDDYG-HFEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKPSLSTSVELPITIVNKAMPVFDKPFYTASVNEDIRMNTPI-LSINATSPEGQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTIRASDALTGARAEVTVDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDADSENNKMVHYQIVQDT-YNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVITLSNHR-KQRMEPLYSLNVSVSDGLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDRFLIDSN-GQVITTERLDRENPLEGDVSIFVRALDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGRGHLVTQVQAIDPDDGANSRITYSLYSEAS-VSVADLLEIDPDNGWMVTKGNFNQLKNTVLSFFVKAVDGGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTAIGSTVDTLRILPSQN-----VWFSTVNGERPENNKGGIFVIEQETGTIKLDKRLDRETSPAFHFKVAATIPLDKVDIVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHSD--------SQPEKVMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVASDLGEAFSLSSTALVSVRVTDINDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITATDGLFVTQAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSNGYIRYSLYGSGNSEFFLDPESGELKTLALLDRERIPVYSLMAKATDGG--GRFCQSNIHLILEDVNDNPPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSLADSAGGVFSIDSSSGIIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRDYLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLDYELCKRFYLVVEAKDGGTPALSAVATVNINLTDVNDNPPKFSQDVYSAVISEDALVGDSVILLIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVKVKKKLDRERVSGYSLLVQAVDSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEEEEFVLDPHGILRSAVVFQHTESLEYVLCVQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTFALKS------EQKSLFKVNSHDGKIIALGGLDSGKYVLNVSVSDGRFQVPIDVVVHVEQLVHEMLQNTVTIRFENVSPEDFVGLHMHGFRRTLRNAVLTQKQDSLRIISIQPVAGTNQ--------------LDMLFAVEMHSS-----EFYKPAYLIQKLSNARRHLEN--IMRISAILEKNCSG--LDCQEQHCEQGLSLDSHALMTYSTARISFVCPRFYRNVRCTCNGGL----CPGSNDPCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLG--------ECSG-------HTSLSFAGNSYIKYRLSENSK----EEDFKLALRLRTLQSNGIIMYTR-ANPCIILKIVDGKLWFQLDCGSGPGILGISGRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQTLSTES-SIYFGALVQADNIRSLTDTRVTQVLSGFQGCLDSVILNNNELPLQNKR-SSFAEVVGLTELKLGC-----VLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDPIG-NTFICNC------------------------------------KAGLTGVTCEEDINECEREECENGGSCVNVFGSFLCNCTPGYVGQYCG--LRPVVVPNIQAGHSYVGKEELIGIAVVLFVIFILVVLFIVFRKKVFRKNYSRNNITLVQDPATAALLNKSNGIPFRNLRG-SGDGRNVYQE---VGPPQVPVRPMAYTPCFQSD---SRSNLDKIVDGLG--GEHQEMTTFHP-ESPRIL--TARRGVVVCSVAPNLPAVSPCRSDCDSIRKNGWDAGTENKGVDDPGEVTCFAG----SNKGSNSEVQSLSSFQSDSGDDN--------------------------------AYHWDTSDWMPGAR--LSDIEEVPNYENQDGGSAHQGSTRELESDYYLGGYDIDSEYPPPHEEEFLSQDQ----LPPPLPEDFPDQYEALPPSQPVSLASTLSPDCRRRPQFHPSQYLPPHPFPNETDLVGPPASCEFSTFAVSMNQGTEPTGPADSVSLSLHNSRGTSSSDVSANCGFDDSEVAMSDYESVGELSLASLHIPFVETQHQTQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QAL3-1", "uniprot_id": "A0A2R8QAL3_DANRE", "id": "A0A2R8QAL3-1", "name": "", "aln": "-------MAVSMALWAG---IWAILLQLALLLFFTVP----PGHCQGERFRLQ--------FTQPLYHASVYENSAARTYAS--SQVRMGIPLQHHSWEVRYRITSGDEEGFFKAEEYTLGDFCFLRIRTKGGNAAILNREVQDNYVLTVKASLKGDT-----LEAWTKVSVQVLDMNDLRPLFSPTTYSVTIAESTPLRTSIAQVTATDADIGSNGEFYYFFKERMELFAVHPTSGVVSLSGKLDVDIQSRYDLEIQAVDRGMKLYGNNGVSSTAKLFVHVERINEHVPTLSIVTLAPVWTEKSP-IIAVVTVEDLDEGKNGEIETVSIVAGDLLELFSIERTDVPSQEMVDEEDSMKGSNEFVLRAMEQFDWDSYPFGLNLSLQARDRGTPQKLSAVQIVHLRLSRPPPVEVTFQKDQYEVLLSEVAPPGTIVEAVKLQPEPDD----AEYILTPSADSGFFSINTMTGVISTARWLTQLKQEVFELEVLEVDSD-------LRVKVKVILEDANDNAPSFAQQSYEVFVNESVAVGTTVVVVTASDDDHGENGYITYSMASLTPLPFSVQQFTGAVTTTQELDFESSLESFSFVVRASDWGSPYRRESEVNITVHLENVNDNKPLFEKVACVGVVSRELPVGEVIATISAIDIDELELVKYKILSGNERGYFELNPDSGVMTLRHSLITAAPKN-SFSLKITATDGEHFSDPMFVNISVVQGKSPPKS--------FSCTETRVAQRLAEKLLKKAKASSKPKMDEGFIDL------FSVNRQTPQFDKSFPTDITVREDVEVGTSVFQVKALDGDTGFNGQLLHAIADGNTDSCFSIGILNGVISIFLPLDREKTDRYLLNITLYDLGQPQRSTWRLLTVYIADANDNAPQFLQDGGYHARISENTPIGTEVIQVEATDKDQGLNGEIQYSLLTSTSQFGINSSSGIVYVAGQLDRELVPLFILKVEARDRAERAAQRFSITTLKITLEDVNDCPPAFIPSVANARALEDLPVGTVIAWLDTQDPDLGLGGQVRYLLDNDYDGR--FEVDKTSGAIRLTKELDYETQQFFNLTVRAKDKGRPVSLLSVSFVELEVVDVNENLYAPYFSSFAMNGSVKESVRIGTSVLQVSARDDDTG-RDGEVQYSIRDGSGLGRFTIDEETGVIYTTDLLDRETQDSYWLTVYATDLGVVPQSAALQVYIQVEDVNDNSPLTSEPMYHATILENSPKDQSVIQIQAQDPDATTAEPRLSFRISSGNPQNFFSINPRTGLITTTSRKLDREQQAEHVLEVTVSDGGSSPRHTTVWVVIQVLDVNDNKPTFPEKMYQVRLPERSRKQRGAPIYRVFAYDQDQGANAELSYSIIDGNEDGKFIIDAKTGVVSSPKKQFSAGTYDILTVKAVDNGRPQRWATARLHIEWIRRPPPNP-IPLAFDEPLYNFT-IMETDRVADIVGVVSAQQQGSASLWFDITGPRSFREMFYILQTACGRNCSTEGGDVDSMFDVEKGVGTIVIAKPLDAEQRSFYNLTLEVTDGTNVANTQVHITVLDNNDNPPVFSQPTYDITITEDTPPDTEVVQVLASDRDERHRLTFSLQSSVDPSSMRLFRIDPNSGVIYTARRLDHESRTQHILTIMVKDQEFPYRRSLARVLIGVEDVNDHAPLFTMVMYDGQVYESAALGSAVLTVTALDKDKGQNAQISYSIDSGNTGNTFRIDPVLGIISLARELDLSSIGHYVLSVKATDNGSPALSSTAVVRIAVTLSNNAGPKFPQNEYQAEISESVAIGTSVVTVNALSLSTLTYDIRHGNGHRTFRINQYSGVITTQKSLDFETVSSYVLIVTASNMAGQASNATITVVVLDQNDNAPVFQQLHYRGSISEGAGLNSVVQSDDGQP---LVIRASDADRNHNALLVYQIMEESARRFFAVDAGTGSIRTIAQLDHETTPTFRFHVNVRDSGHPQLSAERPAEVTIEVQDVNDCSPKFSQDSYEAVLLLPTYEGVEALQVFATDPDGNGQSELTYSLTDG-SLEHFSIEPSTGLLTVRNSTFSKER----FRFNVRVSDGRFSSTALVTVLVHEALDSGLAFTHSAYNANIEENNGNITTVAVVTALGNKLNEPLRYTLLNAGGKFRIKPTSGAIETVGVPLDREEKEEYGLLVQAGREEDR-----LRVARALVRVQVTDVNDNAPVFVGLPYYAAVQVEAEPGTAIFRVTAVDRDKGLNGEVNYFLQDELG-HFEVDRVSGELRLRRAFEADLSSVEYQVLVFARDMGTPPLSSSVTFPVTVVNRAMPVFDRPFYSVKVSEDIPVWTPI-LGINASSPEGQSVLYTITHGDPGTLFSIGFDTGVISVIAGLDYETSPAHRLIVRATDCLTGARAEVDVEVTVLDVNDNPPVFEQPSYKAVISESAMIGTAALQVLATDSDSEKNAAVRYQIIPDR-TNSTDHFHIDSSSGLILTARSLDHETIQRYVFLVKATDNGFPPLSSEVWVTVDVTDTNDNAPVFNQLLYEASINELAPKGHFVTCIQASDADRSDAERLQYGLVSGNERMLFELDAASGVLTLSGQRRMQRMPSAITLNVSVSDGVFTSTAQVHVRVERANLHSPQFTQGMYEADVRENAPPGSKVIAIRAQDADPGPFGDVRYVLLSDAARDLFTIDSS-GQITTLERLDREERSE--MVLSVAAVDAGGRSGYCSVRVTVIDENDNVPLFGASEYHASVRSEVEPGTLVIQVQAWDLDQDANGQVSYSLYSEAS-LQVTELLDIDPDSGWVVTKGNFAPLRGSVLSFLVKASDGGAPIRHSLVSVYIHVLSADAHIPSFSQPQFSFTVPEDMPIGSLLGAVHLHTSTSHSSLPVSFAAVIGQTPESNSEGVFLVDKESGMIKLDKALDRELTQIYHFKVVAMLQQGRLDAVSAVDVEVKVQDVNDNKPAFESDTYETSVTEGLSPGTRILQVRALDPDWAANGQVTYSLAPPGLLGGSGGEDIEEHGAYFTIDSSSGWISTLKGLDHEQNPAHSLTVWAFDLGDPASQSSSTTITIAVSDSNDNIPQFLQPRYYGSVRESDAPGEVVAVLNTRDNDSSPGNRQVTYHITGGNRGGVFALGLVQGEWKLYVKRPLDREEQERYLINVTATDGLYVSTASVDVTVMDTNDNSPVCEPALYSVSVSEDVPLNKQILRVKATDADTGSNAQIQFSLFGSGAEDFFIHPHTGELKTAVALDREKVSRYSLVARATDGG--GLWCEAEVVVDLLDVNDSPPMFSMPHYTTSVYENTATKALLTRIQAIDPDLGVNRKVVYSLVDSADGFFSIDKSSGIVVLERLLDREIQSSYHIVVRASDQGVPVRLSSLANITITVLDINDNPPVFERRDYLATLPEDVAVGTEVVQVYAASKDIGTNADIYYNIRSGNQQGHFTINVNTGAISVSRALDFESCKDYFLTVEATDGGTPPLSAVTMVNINLTDVNDNAPIFSRDAYSVSISEDANIGDTVVKVMAEDVDSYVNGDILYSIISGDRENQFFIEPITGQIKVNKQLDRETMAGYSLSVRALDSGTPAMSSTVLVNIDISDVNDNPPTFTPANHTAVIQENKPLGTSVLQLSVIDKDASHNGPPFHFHILSGNEGAWFKLDREGLLTSNQVFRRSEGTEYVIHVQASDSGRPPLSSVASVLVRVIEESVHKPAASPLHVHIVTMEDEFPGGVIGQIHATDQDAFDILTYGHTH------QQSSLFKVSPRDGRIIALSGLDAGRYTLNATVTDGRFTVSVPVSVHVEQASVEMLHDAVTVRFDRVSPHDFISRHLPSVRRVLSSVMSTSRPDALHVLSVQPVEATGQ--------------LDLLVAVESAEGG----GFYKAALVTQKLSSARRQLDQ--VLRVSAVLDKNCSG--LDCREAQCEQTITLDSHSLLTYSSTKTSFVSPKFHRNTRCVCSDGS----CSAASEVCADMRCPGDMQCVGTDSSRGPYACQCPPGKLG--------ECAG-------HTSLSFSGNSYIKYRVTDGER----SGEMKLALRIRTLQSKGIIMYTR-ADPCSVLKIEEGKLWFQLDCGNSPRSIGISGRLVNDGNWHHVVLELRGNYSSLSLDDMYVERRLTTAKFRPLEADL-SIYFGAQVLPPDARSLTEMKGPRVTNGFQGCLDSVVLNDNELPLQNKR-SPYAEVVGLTDLKLGC-----VLYPDACVAQPCLNGATCISLPSGGFSCSCSALHTGGRCETEISVCMPNPCQNGGVCKPIG-NAFICSC------------------------------------KRGYTGATCEEDVNECERELCENGGICINTFGSFYCNCTPGFVGSACS--VRPVLVPDMQAGHAYVGKEELIGIAVVLFLILTLILLFIAFRKKVFQKSYSRNNLSLVQDPATAALLHKANGGHYPPLRCAIGEPISLYTEGGITGPPQVPVRPMAYTPCFPGD---ARGTLEK-RDGRG--SELTEMSTFHPSESPRILGGTNRRGVVVCSVAPNLPPVSPCRSDCDSLRKSPWE---EDGKVDLLEEVTCFSG----SNKGSNSEVQSLSSFQSDSCDDNASIVTVIRLVNDAVDTIENEVSVMDQGQNFNRAYHWDTSDWLPSTR--LPDIEEVPTYETPEVG-------VALESDYYLGGFDIDSDYPPPQEEEFMSQDQ----LPPPLPT---EEFDTSPANQPVSRESTLSGDRKPRPHFHPSQYLPPHQLP----LG--STGEEFSTFTGREER------------LSVNASSASSVS--SAPCGFEDSETGGS------LDSFEDMHP----HTQQTEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW71-1", "uniprot_id": "FAT2_DROME", "id": "Q9VW71-1", "name": "Fat-like cadherin-related tumor suppressor homolog", "aln": "MFTMKIKKYVTPVKRKAFTILQWISLLCSLWLIPTVQSKADEKHTATLEYRLENQLQDLYRFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRVGLNAEVKYRIISGDKEKLFKAEEKLVGDFAFLAIRTRTNN-VVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVNDKDTGINGNIGRLEIVDGNPDGTFLLKA--------------AETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRF-AYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTN--RILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVN-FPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRP-VIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGG--SPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDP-SLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQ-GSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQ-TITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVN--QSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIH-IKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDDNDQLWYNISN-----------------------GNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSIFFNIISGNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDADN---DTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASDGIFSAILIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRILNPTQLFDIGISSGALKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNGELFKLDRKSGELSIKQHVEG--HNRNYELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAESPLGRSLIYTISSES--QSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNML-NFTDKSSTVLNISVSDGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREKKDE--YVVLLKVSDGGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGNYT-----FKFSIAADQDH-------FMIS-DSGELILQQTLDREQQESHNLIVVAETSTVPVFFAY-ADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESD----------TENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPK-HDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIE--KQEMDFFIVSGDKQAQFQIGKSG---ELFIAKPLDREQLMFYNLSIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQS--KLRFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVP-KLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPLEVTINSFEDDFSGAFIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIGLYKLNVSVSDGKFHVFSIVKINVELVTNDMLKESVVIRFRRISASEFLLSHRKTFMRSIRNIMRCRQKDVILITLQSDYQKASQHAVGNRRARSIDSDLNVVFAVRKQQIIPDSDEFFTSDEIRQTLIDKKNEIENETNLVVEDVLPSTCQSNKNDCVHGECKQILQILKNNVTTTFTDVISFAAPSYIPVNTCVCRPGFDGKHCKETVNACSTDPCSPQRICMPSGSALG-YQCVCPKGFSGTYCERKSSKCSNESCDMGLFTAVSFGGKSYAHYKINKVKAKFTLENGFSYSLQIRTVQQTGTLLYASGKVDYNILEIINGAVQYRFDLGSGEGVISVSSINISDGEWHQISLERSLNSAKVMVDNKHVSHGSAPGVNGILNIQSNDIFVGAEVRP----HPSIIGYEDIQRGFIGCMANIKIAKESLPLYISGGSTIAALKRFTNVEFKCDPSNVLVRLGICGSQPCANSGICKELDTDVFECACQPRYSGKHCEIDLDPCSSGPCLFGGRCDYHGPNNYSCTCPIHLSGKRCEYGKFCTPNPCKNGGICEEGDGISHCMCRGYTGPTCEIDVDECENQPCGNGATCINEPGSFRCICPSYLTGASCGDPLYSNSISTKLKNFSIEHISGIISGVAVVLVIISCVLCCVVLKRSSSSKRRNRLEKDKNKSSYKEANLNS------------LVDKDNYCKPNVKLSNLEVNQRPISYTAVPNDNLVLSNRNFVNNLDILRSYGSAGDELENVPFEYQKVNRNKQHVNINSCHSTDADNAYKQEWCEQMHLRTFSENKLNNELKRDFGPSVSRFSTGKLIQVEMPNVCHSSSANFVDYSALANG-------------------------------QYHWDCSDWVRKSHNPLPDITEVPGAEIADSSSLHSNDSNESKSKKAFFVHREDGDVDPTRDIAALNEDIGSEYLDSEAESCLEPFMLPRSSNQPLSRLSSFNNIENEDYKSNTVPLPSKVSHSCKVYLRHPDSYLPTMHFPSETDGESSMTEGPISRMEIKTRRTISENSEEAYLFPCTVGEIGSNSNISVRLCEIEDSELEEFLPQQQTNN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * ** :. *::. *:.:: *** .:**.. : *:. . :::*** ***:* :***** :.**.** ***: .* .:**** ::*:: :*. :: . *: ::: ::*** *** *** ** *:*.*.*.** *: :*** ***:* ***:** : : *::***:* ::* :*: :.:::* : * *** : :* :*.:*: : ::::* :.* : : .. ..* .:* *:* * * **:* :.** *: * : : :*: :. . . :. : **:: *.* *:*:: : * : * :: *:: :.* :* . * :*:. . . : . :. * **. :*:: **: * *:. : * * : .:*.: ::* **: * * : :**. .*: *: ::*.* * ***.**:**:*.*. :** :::*:* :.**. ****: . : :::****** ***:::*::::: : ::*** * **:* * * :: . *:* : . ****:* :::.*:: .*** * * *:* ** : : .* .: .* *:::**** :::* : :*: :: . .* *.* ** **::***.* * . * . * *: :. * : * * : ** ::::.*.: :* .: ::* * * *:**:::.:*:**: ** * *. * :.:: :***: : *:****:****:* :*: ::*.: : *.*** * .:*. : *.: *** : :.* * * * *.:: *:: .. :* :*:::* : : **** : *:: *:* . . * . : : ::**** .*.* . :. **** ***:* ::: * *:* ..:::: * :: :.. *.:** :**** ****.:*..** * * * * * ** * : : ::***** .:* * .*. *.***. ** *::*:*:* *: :.:: *** .*.*** * :::: * * : . ** ** ****: * * .:** ::***:**: *** ***.:*:*: : * * :: .:* ::* *** . : :::.* *** .:* *: :**:*.**.******:****.***:::*.*.. :* :*:.*** *** * * :::*::::*. : .*::..* * *.* *..::*** .*: ..** **.: * : : : . ::* :** *** *:: ***::* : * . ** . :. *.. : *.*: :* : . . **::* . *: *. * :. *.*:::* ** * :. **:::.***** * *:: : *:* *** * *:: *.:.*:*: :: ::*: *:**** ::* : :::: *. *: **:*. :* : .:.***.* :*** ::*:** * :*. *::::.*.* *** * ** : :..* ****:** : * *:*:*.*.**:: *:* :**.*. *.*:*.:***::. : :: : .::*.:*..* *.*.:*: *:* :::*:* *** :: *: *.: *** * :.* * *:: ::: *: : * ** :***. . :*:* . : * : .:***. :* .: : ::* *** * * .* *::.*.* :.* * . .... *.::..*** . *.:: *:*::. *:.** :*: **:*. : :**:*. . : *.* * * * *:* : ...*.*.* :*** .* *.: :. *:***: .* . :* *.*.*. * :.: :* : : * :: :*::* :* : ::. : : *:.*** * : :*.: * .*:**.: * :. * . **. :::.:.:*..:** *:* :.* :**. * * :**.::*.** :*** :: * *.*:* :* * . : :.: *:***.*:**.:****:*.:: ** * :*.*:* *.. **** * *:. * *::: **:: ::. .:. . :* : : * * . .. *: . : :.:::::****:: **:..:.**: : :.: :.*:* ** *:.::* * . *.*.::** : *: **** . : : :**:*.*:*. *** :.: : *:** * ::. *: .:.* : :** *:: : * ** * : * * *.:: *:** :.* : **:* :: : * * * *.***. * : :.* ***.* * : * : :. * :*:**: :* * * ** : *:* :: **: : :* :**::*.. . **:*****:.*: *:::: : *::** * *. * *:* ** * ::* ::* *.* *.:.:: * ::.: :. * **.. * : : :***: * : : . *.**: :.:::* *:* ***.* * **: * : * . : *:* * * *. : :.: .::. * ::::*: ..* :* *.: . .*:*:* * * * ** :.* *.:: .:: :*:* :.. :.: *. . *: : ::: . . . *: . .: *::. ::* : *:: **:* .:: *.* : . .** :.* * *** * *:. *.: : *. : :* * * * ..**:: * * . *: * ** :***: *..**:* :. ..: * * * *.. .: . ::: : * *** * * .* *. ** *: * * * . :::: :.*..*: . * :* :::: :*****: * :.: *:** :.: * *:: * * ***:* * * *.:. .. ::.*.* * * * ::: * *.* .:* : .:* **. **** . *.*:*:. ** * : : : : *:**. *:** :* ..* *:: ::*:*:::*:* *.*:**:: *** .. . *.*..*:*:: *.: **** * ::: *:* * . * *::.:::.:******** *. *:* .: *:.: **:* *:*:* ***.**:* * * ***:**:* :: .** : : .**:* .: ::*.::* *****.** : *.*.: *:***.* * :: * :.** *..:: : * * ** ** : :.* **. .:* ::* * :.*.: **** :: *:* ::* *.* * ..:. :**:* *.***.* *:.:*::.*:***: :* .* : : * * * .*: * * **** * *: .* * : *.: *::: ::. *.* * * : : *::**** : * . **.: * ::**:*.*..**::**:*** :* *.:. :...**::. . *:* *:..** * * **.:*:**:* * * ::** :**:::*.:** :*. :*: * . * : . : : * : : . :.* *:::.**. . *:.. : *.* . :..::: : : :* ..*.. ** . .*:* : : .: : * : **..* : *.* * * : : * *. : *: :: : * ** * * :*:. .*::**.*:** :*::.. . . :. :*::**:*..* ::*: :*:* :* : :::* *.. :.:*. :.**.** : ** * :.: :*: :*.: :. *. : *:.** * . : : ** **: .: : . .*** . *. * : :*:::: * :: . * .** :.. * * :. :.*:* . .:* .** :: * ..** ** *. * * : *.* * ** *** *::***.: * **. *:* *** * *.. .* *. : . :. ..: . :*. ..*:::*: :: :.:::. * .* : :.. . * *:. : . . :* **::**. .: :. .: : * .. : * * :: . : .: * : . . .: :*. : :: : .*: *: . : .* .* .* . * * **** ***: :: *.** *:* * : . :*. : . *.: *.:: :..* * . . ...** * .::. . : :. . . * : *. : :. * : .* . . .: . . :**: ", "identical_positions": 1338, "similar_positions": 1537, "identity": "27.64%" }, { "cls_id": "homologset.agr.MGI:2444315", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYZ4-1", "uniprot_id": "A0A0G2JYZ4_RAT", "id": "A0A0G2JYZ4-1", "name": "isopentenyl-diphosphate Delta-isomerase", "aln": "-----------------------------------------------------MFQASKTHLNELQIKRLEEILIVIDKQDQIIGADTKRNCH-LMETINKGLLHRGFSVVLFNTQNQLLVQQRADAKYTFPGHFTDSCSSHPLYVPEELEEE-----DAVGVRRAALRRLQAELGIPQDQTSIM-DSIFMNRIYHKSPSDDIWGDHENGYLLLVR-----------DPREVRSYSYMSQEDVQELLDRGTRGEEKITPWFRTIAEGFLLSWWPHLEDVSPFVEPDKIYGL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AD97-1", "uniprot_id": "A0A8I6AD97_RAT", "id": "A0A8I6AD97-1", "name": "isopentenyl-diphosphate Delta-isomerase", "aln": "-----------------------------------------------------MFQASKTHLNELQIKCLEEIVIVIDKQDQIIGADTKRNCH-LMENIDKGLLHRGFSVVLFNTQNQLLVQRRADAKYTFPGHFTDSCSSHPLYVPEELEEE-----DAVGVRRAALRRLQAELGIPQDQISIM-DIIFMNRIYHKSPSDDIWGDHEIGYLLLVRK----DLTLNPDPREVRSYSYMSQEDVQELLDRGTRGEEKITPWFRTIAEGFLLSWWPHLEDVSPFVEPDKIYGL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LU59-1", "uniprot_id": "A0ABK0LU59_RAT", "id": "A0ABK0LU59-1", "name": "isopentenyl-diphosphate Delta-isomerase", "aln": "-----------------------------------------------------MFQASKTHLNELQIKRLEEILIVIDKQDQIIGADTKRNCH-LMENINKGLLHRGFSVVLFNTQNQLLVQQRADAKYTFPGHFTDSCSSHPLYVPEELEEE-----DALGVRRAALRRLQAELGIPQDQISIK-DITFMTRKYQKCQSDAVWGDHEIGYLLLVRK----DLTLNPDPREVRSYSYMSQEDVQELLDREARGAEKITPWFRSMVEDFLLPWWPYLEDVSPFVEPDKIYGL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFZ6-1", "uniprot_id": "IDI2_MOUSE", "id": "Q8BFZ6-1", "name": "Isopentenyl-diphosphate delta-isomerase 2", "aln": "-----------------------------------------------------MFQASKTHLDELQLKRLEEMCIVIDKQDQIIGADTKKNCH-LMENINKGLLHRAFSVVLFNMKNELLVQQRADAKYTFPGHFTDSCSSHPLYVPEELEEK-----DALGVRRAALRRLQAELGISQDQISIK-DIIFMTRKYHKCQSDAIWGEHEIGYLLLVRK----DLMLNPDTREVRRCCYMSQKDVQELLDREARGEEKITPWFRSMVEDFLFSWWPHLEDVSSFVEPDKIYGL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXS1-1", "uniprot_id": "IDI2_HUMAN", "id": "Q9BXS1-1", "name": "Isopentenyl-diphosphate delta-isomerase 2", "aln": "-----------------------------------------------------MSDINLDWVDRRQLQRLEEMLIVVDENDKVIGADTKRNCH-LNENIEKGLLHRAFSVVLFNTKNRILIQQRSDTKVTFPGYFTDSCSSHPLYNPAELEEK-----DAIGVRRAAQRRLQAELGIPGEQISPE-DIVFMTIYHHKAKSDRIWGEHEICYLLLVRK----NVTLNPDPSETKSILYLSQEELWELLEREARGEVKVTPWLRTIAERFLYRWWPHLDDVTPFVELHKIHRV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P15496-1", "uniprot_id": "IDI1_YEAST", "id": "P15496-1", "name": "Isopentenyl-diphosphate delta-isomerase", "aln": "MTADNNSMPHGAVSSYAKLVQNQTPEDILEEFPEIIPLQQRPNTRSSETSNDESGETCFSGHDEEQIKLMNENCIVLDWDDNAIGAGTKKVCH-LMENIEKGLLHRAFSVFIFNEQGELLLQQRATEKITFPDLWTNTCCSHPLCIDDELGLKGKLDDKIKGAITAAVRKLDHELGIPEDETKTRGKFHFLNRIHYMAPSNEPWGEHEIDYILFYKINAKENLTVNPNVNEVRDFKWVSPNDLKTMFADPS---YKFTPWFKIICENYLFNWWEQLDDLSEVENDRQIHRML", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VDC2-1", "uniprot_id": "Q9VDC2_DROME", "id": "Q9VDC2-1", "name": "isopentenyl-diphosphate Delta-isomerase", "aln": "-----------------------MLASRLNLLLPRVSWLRGCSTTAVGQKHQRQVPTEFAVHDPLQAHALKEQCILVDANDQAIGAASKADCHRVHPETNDVKLHRAFSVFLFNSQGEMLVQKRSSHKITFPNTYTNACCSHPLYEIEQERQER----NAQGIRVAAQRRLNYELGIPTEELQPQ-DFRYLTRIHYADTGDGVWGEHEIDYILFLQK----DVTLRPNSNEVSEVRYLRRDKIDEAVAKFS---APLTPWFSLILQHRLKLWWDNLHQLEQFEDLSNIQRF-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : ::* *::* :*: *** :* ** : :. ***.***.:** :..:*:*:*: * ***. :*::*.**** : : . * ** *:*: ****. :: . . ::. : .: **:** *:*: : : *. :: ..: . : .***: : : * ** *.:: . : :* . ", "identical_positions": 56, "similar_positions": 67, "identity": "19.18%" }, { "cls_id": "homologset.agr.MGI:2444329", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAB3-1", "uniprot_id": "D4AAB3_RAT", "id": "D4AAB3-1", "name": "", "aln": "MSDQERETEEDEG--VTSDTAPMLPRRRPTDYHISVLA----TQGLR-TLMLSARALAGFLLHLLLPGTVFLLVLLPAAAVVYLGFLCHSRVHPAPGPRCRALLSDRGSAALIVFGFLSLPPLLVLASAARSLLVRRLHLVLPTPARTPDPRRLPRGSEDLAD----EEKHLCAWV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TYP4-1", "uniprot_id": "TM278_MOUSE", "id": "Q3TYP4-1", "name": "Transmembrane protein 278", "aln": "MSEQERETEEDEG--VASDTAPMLPRRRPTDYHISVLAPILATRGLG-TLVLSGRALVGFLLHLLLPGTVFLLVLLPAAAVVYLGFLCHSRVHPAPGPRCRALLSDRGSAALIVFGLLSLPPLVVLAAAARSLLVRRLRPALPDPARTPAPRRPPRSSGDLADGHPDEDKQLCAWV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NKF7-1", "uniprot_id": "TM278_HUMAN", "id": "A6NKF7-1", "name": "Transmembrane protein 278", "aln": "MSEQGRETEEEEGGGGASDTAPMLPRG-PPDHQASALT----CPGWSGPPLLPGRLLAGLLLHLLLPAAAFLLVLLPAAAVVYLGFLCHSRVHPAPGPRCRALFSDRGSAALIVFGLLSLPPLLVLASAVRARLARRLRPLLPPPAGTPGPRRPP-GRPD-------EDEQLCAWV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* *****:** :********* *.*:: *.*: * . :*..* *.*:*******.:.*********************************:************:******:***:*.*: *.***: ** ** ** *** * . * *:::*****", "identical_positions": 112, "similar_positions": 29, "identity": "63.64%" }, { "cls_id": "homologset.agr.MGI:2444335", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PDF3-1", "uniprot_id": "SVOPL_MOUSE", "id": "Q6PDF3-1", "name": "Putative transporter SVOPL", "aln": "MAAK-----QTEPVTIISLRKLSQAAPE------------PQQKETK--TFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAV-VSPVIRCEWQ--LENWQVAFVTTMVFFGYMVSSILFGLLADRYGRWKILLLSFLWGAYFSLLTSFSPS------YIWFVFLRTMVGCGVSG-HAQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIISMASVVIPTIG-----------------------WRWLIRIASIPGIILIMAFKFIPESARFNVST-GNTQAALNTLESIAKMNRSVMPEGQLVEPILEKRGRFADLLDSKYLRTTLQIWIIWLGISFAYYGVILASA-ELLERDLVCGSKSESEPEVVETTGDSGEGLSPCYCHIFAPSDYRTMIISTLGEIALNPLNILGINFLGRR-LSLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFN---TIYIYTAEVYPTPMRAIGMGTSGSLCRIGAMVAPFISQVLMSA----------SFLGALCLFSSVCVVCAISAFTLPIETKGRALQQIK---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A9T9-1", "uniprot_id": "D4A9T9_RAT", "id": "D4A9T9-1", "name": "", "aln": "MAAK-----QTEPVTIISLRKLSQAAPE------------PQQKETK--TFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAV-VSPVIRCEWQ--LENWQVAFVTTMVFFGYMVSSILFGLLADRYGRWKILLLSFLWGAYFSLLTSFSPS------YIWFVFLRTMVGCGVSG-HAQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIISMASVVIPTIG-----------------------WRWLIRIASIPGIILIMAFKFIPESARFNVST-GNTQAALDTLESIAKMNRSVMPEGRLVEPILEKRGRFADLLESKYLRTTLQIWIIWLGISFAYYGVILASA-ELLERDLVCGSKSESEPEVVENMGDAEEGRSPCYCHMFAPSDYRTMIISTLGEIALNPLNILGINFLGRR-LSLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFN---TIYIYTAEVYPTPMRALGMGTSGSLCRIGAMVAPFISQVLMSA----------SFLGALCLFSSVCVVCAISAFTLPIETKGRALQQIK---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N434-1", "uniprot_id": "SVOPL_HUMAN", "id": "Q8N434-1", "name": "Putative transporter SVOPL", "aln": "MATK-----PTEPVTILSLRKLSLGTAE------------PQVKEPK--TFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAV-VSPVIRCEWQ--LENWQVALVTTMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSFAPS------YIWFVFLRTMVGCGVSG-HSQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVIIPTIG-----------------------WRWLIRVASIPGIILIVAFKFIPESARFNVST-GNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGRFADLLDAKYLRTTLQIWVIWLGISFAYYGVILASA-ELLERDLVCGSKSDS--AVVVTGGDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRR-LSLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFN---TVYIYTAEVYPTTMRALGMGTSGSLCRIGAMVAPFISQVLMSA----------SILGALCLFSSVCVVCAISAFTLPIETKGRALQQIK---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LVS8-1", "uniprot_id": "SVOPL_DANRE", "id": "Q1LVS8-1", "name": "Putative transporter SVOPL", "aln": "MALKRSSSMKTQLVDAIQLEEVEMEEEITTTSNNNNPVEPAQVKEPK--CYTVEEAVESIGFGCFHILLFVIMGSANIVEAMEIMLLAV-VSPEIRCEWH--LEDWQVALVSTMVFFGFMVCGVLCGYIADKYGRWKVVFGGFVWASYFSFLTSFSTS------YGWFIFLRCMVGCGVAA-TSQGFVLKTEFIPAKYRAYLLPLASIFWMMGSILIIVLGMTVVPTMG-----------------------WRWMIRFSVIPSLVLIGLFMFIPESARFQVSA-GNIQGAMSTLKRIAKMNNGVLPEGELREPEVTERGNAVTLISSAFRRTSLLLWYSWFVASFSYYGSVLSSS-ELLEKNLLCVTDPDLEHQIKHIQEET-----LCYCIPFNSDDYQTLLISCLGEVALIPLNIILLNIVGRK-YSMVILLLLSAFFFMLVNICTTMLGFTILLFLLRSVVSMNFN---VVYIYTAEVYPTSVRSIGMGFCTSFSRIGGMIAPFIAQVLMSK----------SVILALSPFATACIICAIGVFFLPIETRGRALLQDA---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25297-1", "uniprot_id": "PHO84_YEAST", "id": "P25297-1", "name": "Inorganic phosphate transporter PHO84", "aln": "MSSVN---KDTIHVAERSLHKEHLTEGGNMAFHNHLN-DFAHIEDPLERRRLALESIDDEGFGWQQVKTISIAGVGFLTDSYDIFAINLGITMMSYVYWHGSMPGPSQTLLKVSTSVGTVIGQFGFGTLADIVGRKRIYGMELIIMIVCTILQTTVAHSPAINFVAVLTFYRIVMGIGIGGDYPLSSIITSEFATTKWRGAIMGAVFANQAWGQISGGIIALILVAAYKGELEYANSGAECDARCQKACDQMWRILIGLGTVLGLACLYFRLTIPESPRYQLDVNAKLELAAAAQEQDGEKKIHDTSDEDMAINGLERASTAVESLDNHPPKASFKDFCRHFG-QWKYGKILLGTAGSWFTLDVAFYGLSLNSAVILQTIGYAG---SKNVYKKLYDTAVGNLILICAGSLPGYWVSVFTVDIIGRKPIQLAGFIILTALFCVIGFAYHKLGDHGLLALYVICQFFQNFGPNTTTFIVPGECFPTRYRSTAHGISAASGKVGAIIAQTALGTLIDHNCARDGKPTNCWLPHVMEIFALFMLLGIFTTLLIPETKRKTLEEINELYHDEIDPATLNFRNKNNDIESSSPSQLQHEA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * * .*.: .: ::. . :::: *** :: : * * :.:: :*: : : :: *: : . . :::.. . .* :: . * :** ** :: :: ::* : . : * * ::* *:.. . . ::.:** .:*:*. :: *.: :. ::.: ** :* .. : .: : ****.*:::.. .: . * : : .: : .: : : . . . :. :::: : : .: * :*.:: . : :: . : : : .::: *.:. :.:: ::::**: .: : :*:* :: . . : : : . . **. . :* ..* :** *: . * . : ::*.::* .*:. . : : : : :: .* . * **: ::* : ", "identical_positions": 59, "similar_positions": 187, "identity": "9.92%" }, { "cls_id": "homologset.agr.MGI:2444336", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQD3-1", "uniprot_id": "A0A8I5ZQD3_RAT", "id": "A0A8I5ZQD3-1", "name": "Mucin-2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNPGHGSSFESTLDK---KKKISSSLALVT-----------------------------FQVLSSHRGSVAPLSTTGKGERESARHHRVFCGTAWAD---------------------------------------------------------------------------MAAIWRSNYGMGSPWSWWALWAG----------------------------------------AILLWARLTPTEASCQGVQCASGQRCQMVSGKARCVAESTAVCRAQGDPHYTTFDGRRYDMMGSCSYTMAELCGSDETLPAFSVEAKNEHRGSRQVSYVGLVTVYAYSHSVSMVRGETGFIRIDNQRSRLPASLSEGRLRVYQSGTRGIIELDFGLVISYDWDSQLTLSLPKRFQDQVCGLCGNYNGDPADDFLTPDLEQAPNALEFANSWKLDDGDYLCDDGCHNSCPSCTPGQMQHYKGDRLCGMLALSTGPFSACHELLDPKPFLEDCVFDLCVTGGERLSLCRSLSAYAQACVELGVTLENWRQPSNCPMSCPANSCYDPCSPACPASCNSEALPSNCSSRPCVEGCVCLPGFVASGGDCVPVSSCGCTYQGRPLAPGQEVFADDQCQRRCTCDGATQKVTCRDTSGCPSGEHCNVQNGLLGCYPDNFASCQASGDPHYVSFDGKRFDFMGTCTYLLVGSCGQNAALPAFKVLVENEHRGSQTVSYTRAVRVVAHGVEVAVRRENPGRVLVDGVLQYLPFQAAGGKVRVYRQGNDAVVSTDFGLTVTYNWDAHVTAKVPNSYAKAVCGLCGNFNGNPDDDLALKGGGQANNVLDFGNSWQEEIIPGCGATTPGDCPQLDSLVTQQTQSKKECGILADPEGPFRECHKLLNPQGAIRDCVYDLCLLPGQSGPLCEALAAYAAECQAAGGTVHPWRSEKLCPLTCPPNSHYELCSYGCPLSCGDLPVPGGCGSECRESCVCDEGFALSGESCVPLASCGCVYQGAYHSPGETFYPGPGCESLCHCEEGGLVSCEPSSCGPHEACQPSNGVLGCVAVGTTTCQASGDPHYITFDGRRFDFMGTCVYVLAQTCGTRPGLHQFTVLQENEPWGNGKVSVTKVITVLVANYTLRLEQNQWKVKVNGVDMKLPVVLDGGKIRVSQHGSDAVIETDFGLRVAYDLVYSVRVTIPGNYYQQMCGLCGDYNGDPKDDFQKPDGSQATNPSDFGNSWEEAVPDSPCAPVPPCTG--DDCNP--ACSPELENKYSGEKFCGLLTNPTGPLAACHKLLDPQGPLKDCVFDLCLGGGNQSILCNNIHAYVSACQEAGGQVEPWRTETFCPMKCPPHSHYEVCADTCSLGCWALSTPQKCPEVCAEGCECDSGFLYNGKACVPIQECGCYHNGVYYEPEESVLIENCQQHCVCHPGTGMVCQDHSCKPGEVCEPSGGVLTCITKDPCHGITCRPQETCKVEGGEGVCVPNYHATCWLWGDPHYNSFDGWSYDFQGTCNYLLAGTICPGINAEGLTPFTVTTKNENRGNPAVSYVRLVTVTTLNTNISIHKNEIGKVRVNGALVTLPVYLAGGRISVINGGSKAVLETDFGLQVTYDWNWRVEVTLPSSYHSAVCGLCGNMDKKPENDKVFPNGTVAPSIPAWGGSWQVPGWDPLCWNECQGSCPTCPEDRVEEYEGPGFCGPLAPGTG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPFASCHSHVPPESFFKGCVLDVCLGGGNKDILCQALAAYAAACQAAGIKIEDWRTQAGCEIPCPDNSHYELCGPRCPASCPPPAQHTPPTACDGPCVEGCQCDQGFVLSADQCVPLDGGCGCWVNGTYHEAGTEFWTDTTCSKRCHCGPGGDSLICKSASCGLGEECALLPSGEIGCQPTSIAECEAWGDPHYTTLDGHRFDFQGTCEYLLSAPCHAPPPGIEYFNVTVANEHRGSQAVSYTRSVTLHIYGLSLTLSAQWPRQLQVNGEFVALPFHLDQKLSVYISGADVVVNTASGLSLAFDGNSFVRLRVPAAYAGSLCGLCGNYNKNPNDDLTAVDGKPEGWKVGGAPGCDQCQPEPCPQPCTPEQQEPFRGPDACGIITAPEGPLAPCHSLVPPTKYFEACLLDACQVQGHPGGLCPAIATYVAACQAAGAQLGEWRKPDFCPLQCPANSHYQLCGDSCPVSCPSLSAPEGCETTCREGCVCDSGFVLSGDTCVPVGQCGCLYNGRYYVLGATFYPGPECERLCECGPGGQVTCQEGADCEPYEECRVENGVQACHPTGCGHCLANGGVHYVTLDGRVYDLHGSCSYVLAGVCRPKPGEEEFSIVLEKDSAGEPQRVVVTVADQVVVLARGPQVTVDGEAVALPVATAHVSVTAEGRNVVLQTNKGMKVLFDGDAHILMSIPSSFRGRICGLCGNFNGNWSDDFVLPGGAVAPNVDAFGAAWRAPSSSLGCSEGCGPQGCPVCLAEETEAYEKNDACGKIRDPKGPFATCHKVLSPLEYFRQCVYDMCAHKGDKAYLCRSLAAYTAACQASGAAVKPWRTDSFCPLQCPAHSHYSVCTRSCQGSCAALSGLTGCTTRCFEGCECDDHFLLSQGVCIPAQDCGCVHNGQYVPVNSSLMSSDCSELCYCSETTGLTCRAAGCPSGQVCEIQAGVRQCRAAHGLCSLSVGANLTTFDGALNTISSPGVYELSSRCPGFQKNVPWYRLLADVQPCLNNDKIVSKVHIFFQDGMVTVIPSKGAWVNGLRVDLPATVLTSVSVKKMPDGSMFVHQKAGVQVWLGKDGHLDVMVGDDHAAVLCGVCGNFDGDQTNDAHGSQGKTTIEKWRAQDFSPCPN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q9C6-1", "uniprot_id": "E9Q9C6_MOUSE", "id": "E9Q9C6-1", "name": "Mucin-2", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSPWKWWALWAG----------------------------------------ATLLWALLTPAEASCQGIQCASGQRCQMVSGKARCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMAELCGSDETLPAFSVEAKNEHRGSRQVSYVGLVTVYAYSHSVSLVRGEIGFVRIDNQRSRLPASLSEGRLRVHKSGTRGVIEMDFGLVVTYDWDGQLTLSLPKRFQDQVCGLCGNYNGDPADDFLTPDLDQAPDALEFANSWKLDDGDYLCDDGCHNSCPSCTPGQTQHYKGDRLCGMLTLSTGPFSACHEFLDPKPFLDDCVFDLCVTGGERLSLCRSLSAYAQACVELGVTLENWRLPASCPMSCPANSCYDPCSPACPPSCNSEAVPTNCSSRPCVEGCVCLPGFVASGGDCVPVSSCGCIYQGRLLAPGQEVFDDDRCRRRCTCDGATQKVTCRDTTGCPSGERCNVQNGLLGCYPDNFASCQASGDPHYVSFDGKRFDFMGTCTYLLVGSCGQNAALPAFKVLVENEHRGSQTVSYTRAVRVVAHGVEVAVRRENPGRVLIDGVLQYLPFQAAGGKIQVYRQGNDAIVSIDFGLTVTYNWDAHVTAKVPSSYAKDVCGLCGNFNGNPDDDLALKGGGQASNVLDFGNSWQEEIIPGCGATEPGDCPQLDSLVTQQIQDKKECGILADPEGPFRECHKLLNPQGAIRDCVYDLCLLPGQSGPLCDALAAYAAACQAAGGTVHPWRSEELCPLTCPPNSHYEQCSYGCPLSCGDLPVQGGCGSECREGCVCNEGFALSGESCVPLASCGCVHEGAYHAPGETFYPGPGCDSLCHCEEGGLVSCEPSSCGPQEACQPSNGVLGCVAVGTTTCQASGDPHYVTFDGRRFDFMGTCVYVLAQTCGNRPGLHQFTVLQENEAWGNGKVSVTKVITVLVANYTLRLEQSQWKVKVNGVDTKLPVMLDGGKIRVSQHGSDVVIETDFGLRVAYDLVYYVRVTIPGNYYKQMCGLCGDYNGDPKDDFQKPDGSQTTDPSDFGNSWEEAVPDSPCAPVPPCTG--DDCDT--ECSPELQDKYHGEQFCGLLTSPTGPLAACHKLLDPQGPLQDCVFDLCLGGGNQSILCNIIHAYVSACQAAGGQVEPWRTETFCPMECPPHSHYEVCADTCSLGCWALNTPQQCPEGCAEGCECDSGFLYNGKACVPIEQCGCYHNGVYYEPEESVLIENCQQHCVCQPGKGMMCQDHSCKPGQVCEPSGGVLTCVTKDPCHGITCRPQETCKVQGGEGVCVPNYNSTCWLWGDPHYNSFDGWSFDFQGTCNYLLAGTLCPGVNAEGLTPFTVTTKNENRGSPAVSYVRQVTVTTLNTNISIHKNEIGKVRVNGVLMALPVYLAGGRISVINGGSKAVLETDFGLQVTYDWNWRVDVTLPSSYHGAVCGLCGNMDKNHQNDQVFPNGTMAPSIPTWGGSWQVPGWDPLCWHECQGSCPTCPEDRVEEYEGPGFCGPLAPGTG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPFTSCHAHVPPESFFKGCVLDVCLGGGSKDILCQALAAYAAACQAAGIKIEDWRTQAGCEITCPDNSHYELCGPPCPASCPPPARHTAPTVCDGPCVEGCQCDEGFVLSADQCVPLDGGCGCWVNGTYYEAGTEFWADTTCSKRCHCGPGGDSLVCKPASCGLGEECALLPSGEIGCQPTSITECQAWGDPHYTTLDGHRFDFQGTCEYLLSAPCHEPPTGTEYFNVTVANEHRGSQAVSYTRSVTLQIYGLSLTLSAQWPRKLQVNGEFVALPFHLDQKLSVYISGADVVVNTASGVSLAFDGDSFVRLRVPAAYAGTLCGLCGNYNKNPNDDLTAVGGKPEGWKVGGAPGCDQCEPEPCPKPCTPEEQEPFRGPDACGIITAPEGPLAPCHSLVPPTQYFEACLLDACQVQGHPGGLCPAIATYVAACQAAGAQLGEWRKPDFCPLQCPAHSHYQLCGDSCPVSCPSLSAPVGCETICREGCVCDAGFVLSGDTCVPVGQCGCLYQGRYYVLGATFYPGPECERLCECGPDGQVTCQEGADCEPYEECRIENGVQACHPTGCGHCLANGGLHYVTLDGRVYDLHGSCSYVLASVCHPKPGDEEFSIVLEKNSAGDPQRVVVTVAGQVVGLARGPQVTVDGEVVTLPVATGHVSVTAEGRNIVLQTNKGMKVLFDGDAHILMSIPSSFRGRLCGLCGNFNGNWSDDFVLPSGAVAPNVEAFGTAWRAPGSSLGCGEGCGPQGCPVCLAEETQAYEKNDACGKIRDPHGPFAACHKVLSPLEYFRQCVYDMCAHKGDKAYLCRSLAAYTAACQAAGAAVKPWRTDSVCPLQCPAHSHYSICTRSCQGSCAALSGLTGCTTRCFEGCECDDHFLLSHGVCIPAQDCGCVHNGQYMPVNSSLMSSDCSERCFCSPNNGLTCHEAGCPSGHVCEIQAGVRECQAARGLCSISVGANLTTFDGAHNAISSPGVYELSSRCPGLQKNVPWYRVLADVQPCHNNDKIVSKVHIFFQDGLVTVIPSKGAWVNGLRVDLPATVLTSVSVRRMPDGSMLVHQKAGVTVWLGKDGLLDVMVGDDLAAMLCGACGNFDGDQTNDAYGSQGKTPIEKWRAQDFSPCSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6R7-1", "uniprot_id": "FCGBP_HUMAN", "id": "Q9Y6R7-1", "name": "IgGFc-binding protein", "aln": "MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSPCYG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: .* *: .. * : *:*.*.**:*:***:*****:*.*** *****************************:*****.***..*:*****************:********* *******:.*** **: :********.*********::**.*.::*: ****::**** **:**** ************************* **:*:***.***********:***:*.**:***** ***:********: ***:.**: ***:***::**:****.*********.********:***::: :** *:.**:****** *: *.****.***. * *:***.****************** ***.***** :** *******: *: *:*****:***::*****. .**:**:*.***********.*.:**.***********:*************************:********************* *:**:****** **:**:*.**********.*:::*:***.**:* ********:*:*:******.***: :*********:* *****:***** *.* ******** ****** *****:*****:** *.*:********:*******. *:****:****** ***********:***:*** *****.********:****:***:**** ************** *******:*.***:**********:********::*:**.**:********:*****:********.*****:******.* *******::********** **********************.*****:*:***** .****:****:**** ***:****** ****.***** ****:* .*:**.******.**************** ****:*****:*******:************:***: :..:*******.****** * .**. :** . *.***:.** *:*****:.*****::****:******:**:********* ****. ********* ***:************:***:****:********* **.:* :* : *****:*********:*****::*************::***:**:*:*.*:.*.**:**:******:**:****:*:*:*******:********* :**:***:***.:**********:**** .:********:** * ***:.::***********:***.******* ***::*.*******:*********.* :*** :*.***** :*.***:* :******:*******:********.**********:: :**:******:***** *****:.********.**:**********:*:*************** .**::**:****************:***.:****:***:*.*******: *****:*.****.**:*****:*** ******.** *.*:.*:********** *******:****:.*****.****:***:***:* ***: *:*****.**:*..******* *.*****: ****.* :**:*******.********************** ** * * *.*********************:**. ******:***:***:* ******:**. * .::*******.*:**:******:************.:*********::* ***.**.*** **:**** **.:* .:***.*****:**.* ******:*:*.:*******.****::**:.******************:******************:**********:***:**************** ***: ********:******************::**** ** .********* *****.*:******* * *:****:*:******.****:******:**:****************** **:****:*:*******::**: **::****.*** **:* *******.*:****..:* *******:****.**:::*******:******.****:******************.*:.*..*::**:*****.** **.**************** .**.*:***::*:*:****:*: **** *********:**:*****:**************:*.*********.***:********:***:**************************:****:*****.*****.***:*:******::***** * ** ..****: ****.*:***::* .*:* *::*** :************ .: :*************:*:.:****::*:** * .: : *.:********:**: *.**.*********** *:**** : ****::*:***** **** :* : *:*.:* *. ***.*********** :.** *..:*********** .", "identical_positions": 1978, "similar_positions": 451, "identity": "36.6%" }, { "cls_id": "homologset.agr.MGI:2444341", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AD31-1", "uniprot_id": "D4AD31_RAT", "id": "D4AD31-1", "name": "Histone lysine demethylase PHF8", "aln": "------------------------------------MASVPVYCLCRLP-YDVTRFMIECDMCQDWFHGSCVGVE---------------EEKAADIDLYHCPN---CEVLHGPSIMKKRRGSSKGHDN----HKGKPLKTGSSMFIRELRGRTFDSSDEVILKPTGSQLTVEFLEENS----------------FSVPILVLKKDGLGMTLP-----SPSFTVRDVEHYVGSDKEIDVIDVARQADCKMKLGDFVKYYY---SGKREKVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEECVFE------------RPNVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQNEMFFGDQVEKCYKCSVKQGQTLFIPTGWIHAVLTPVDCLAFGGNFLHSLNIEMQLKAYEIEKRLSTADLFKFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTRKEALPDHEDEIPETVRTVQLIKDLAREIRLVEDIFQQNVGKTSNIFGLQRIFPAGSIPLTRPAHSTSVSMSKLSLPSKNGSKKKGLKPKDIFKKAERK---GKQSSALGPAGQLSYNLMDPYSHQALKTGPSQKAKLNIGGACLNDSDDDSADMDVDGSENPLALLMANGSTKRMKSVSKSRRAKIAKKVDSARLVAEQVMGDEFDLDSDDELQIDERLGKEKANLLMRSK----FPRKLPRAKPCSDPNRIREPGEVEFDIEEDYTTDEDMVEGVESKLGNGSGAGGILDLLKASRQVGGPDYAALTEAPASPSTQEAIQGMLCMANLQSSSSSPATSSLQAWWTGGQDRSSGSSSSG-LGTVSNSPISQR-----TPGKRPIKRPAYWKNESEEEE-NASMDEQDSLGACFKDAEYIYPSLESDDDDPALKSRPKKKKNSDDAPWSPKARVTPTLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQKAQ-KKKYIKKKPLLKEVEQPRPQDSNTTMTMPAPTLATTPQPVTSSSPQPPPEPKQEALSGSLADHEYTARPNAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSSQ-------------------AGQGKRPKKGLATAKQRLGRILKIHRNGKLLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TJ7-1", "uniprot_id": "PHF8_MOUSE", "id": "Q80TJ7-1", "name": "Histone lysine demethylase PHF8", "aln": "------------------------------------MASVPVYCLCRLP-YDVTRFMIECDMCQDWFHGSCVGVE---------------EEKAADIDLYHCPN---CEVLHGPSIMKKRRGSSKGHDN----HKGKPLKTGSSMFIRELRGRTFDSSDEVILKPTGSQLTVEFLEENS----------------FSVPILVLKKDGLGMTLP-----SPSFTVRDVEHYVGSDKEIDVIDVARQADCKMKLGDFVKYYY---SGKREKVLNVISLEFSDTRLSNLVETPRIVRKLSWVENLWPEECVFE------------RPNVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQNEMFFGDQVEKCYKCSVKQGQTLFIPTGWIHAVLTPVDCLAFGGNFLHSLNIEMQLKAYEIEKRLSTADLFKFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTKKEALPDHEDEIPETVRTVQLIKDLAREIRLVEDIFQQNVGKTSNIFGLQRIFPAGSIPLTKPAHSTSVSMSKLSLPSKNGSKKKGLKPKDIFKKAERK---GKQSSALGPAGQLSYNLMDPYSHQALKTGPSQKAKFNMSGTSLNDSDDDSADMDLDGSENPLALLMANGSTKRMKSVSKSRRAKIAKKVDSARLVAEQVMGDEFDLDSDDELQIDERLGKEKANLLIRSK----FPRKLPRAKPCSDPNRIREPGEVEFDIEEDYTTDEDMVEGVESKLGNGSGAGGILDLLKASRQVGGPDYAALTEAPASPSTQEAIQGMLCMANLQSSSSSPATSSLQAWWTGGQERSSGSSSSG-LGTVSSSPASQR-----TPGKRPIKRPAYWKNESEEEE-NASLDEQDSLGACFKDAEYIYPSLESDDDDPALKSRPKKKKNSDDAPWSPKARVTPTLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQKAQ-KKKYIKKKPLLKEVEQPRPQDSNPIMTMPAPTVATTPQPDTSSSPQPPPEPKQEALSGSLADHEYTARPNAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSSQ-------------------AGQGKRPKKGLATAKQRLGRILKIHRNGKLLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPP1-1", "uniprot_id": "PHF8_HUMAN", "id": "Q9UPP1-1", "name": "Histone lysine demethylase PHF8", "aln": "MNRSRAIVQRGRVLPPPAPLDTTNLAGRRTLQGRAKMASVPVYCLCRLP-YDVTRFMIECDMCQDWFHGSCVGVE---------------EEKAADIDLYHCPN---CEVLHGPSIMKKRRGSSKGHDT----HKGKPVKTGSPTFVRELRSRTFDSSDEVILKPTGNQLTVEFLEENS----------------FSVPILVLKKDGLGMTLP-----SPSFTVRDVEHYVGSDKEIDVIDVTRQADCKMKLGDFVKYYY---SGKREKVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEECVFE------------RPNVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQNEMFFGDQVDKCYKCSVKQGQTLFIPTGWIHAVLTPVDCLAFGGNFLHSLNIEMQLKAYEIEKRLSTADLFRFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTRKEALPDHEDEIPETVRTVQLIKDLAREIRLVEDIFQQNVGKTSNIFGLQRIFPAGSIPLTRPAHSTSVSMSRLSLPSKNGSKKKGLKPKELFKKAERK---GKESSALGPAGQLSYNLMDTYSHQALKTGSFQKAKFNITGACLNDSDDDSPDLDLDGNESPLALLMSNGSTKRVKSLSKSRRTKIAKKVDKARLMAEQVMEDEFDLDSDDELQIDERLGKEKATLIIRPK----FPRKLPRAKPCSDPNRVREPGEVEFDIEEDYTTDEDMVEGVEGKLGNGSGAGGILDLLKASRQVGGPDYAALTEAPASPSTQEAIQGMLCMANLQSSSSSPATSSLQAWWTGGQDRSSGSSSSG-LGTVSNSPASQR-----TPGKRPIKRPAYWRTESEEEEENASLDEQDSLGACFKDAEYIYPSLESDDDDPALKSRPKKKKNSDDAPWSPKARVTPTLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQKAQ-KKKYIKKKPLLKEVEQPRPQDSNLSLTVPAPTVAATPQLVTSSSPLPPPEPKQEALSGSLADHEYTARPNAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSNQ-------------------AGQGKRPKKGLATAKQRLGRILKIHRNGKLLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CH95-1", "uniprot_id": "PHF8_DANRE", "id": "P0CH95-1", "name": "Histone lysine demethylase PHF8", "aln": "------------------------------------MASVPVYCLCRLP-YDVTRFMIECDVCQDWFHGSCVGVE---------------EDKAAEIDLYHCPN---CQVTHGPSVMRKRRGAVKHADVGLGRDSGRPVKTGSAQFVRELRCRTFPSADEVLLKPTGAQLTVEFLEERS----------------FSVPVLVLRKDGLGMNLP-----PSSFSVTDVEHYIGTEKEIDVIDVSRQADLKMKLGEFVEYYN---SPNRDRVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEESIFE------------RPNVQKYCLMGVKDSYTDFHIDFGGTSVWYHVLRGEKIFYLIRPTAANLSLFERWSSSSNQNELFFGDQVDMCYKCSVKQGNTLFIPTGWIHAVLTPVDCLAFGGNFLHSLNIDMQLRAYEIEKRLSTADLFKFPNFETVCWYVGKHLLDTFRGLRENRRHPATYLVHGAKALNNAFRGWTRKESLGEHEQEIPDTIKTQQLVKDLAKEIRLVEDIFQQNIGRSGTPFGGSQGLPS---PHPKAQLNTPLTFS------QHLSKKRGPKPKEAFGGGGVGPPGAKKKSQKGKEIKTEAGELDLLEIHTKHTLKKFQPGCKVKKSKLELPDDCLDDFEEKINKSKLKLVLTNG-----KLQGKKGRAGSANGAGSSLQQFQPHMATLSDFDSEDELQIDETPPPRRRPSLPSKKKLAGLPRKLPRAKPCSDPHRIREPGEVDFDIEEDYTTDEEMLT----MQGVKGGAGGILDLLKASKQVAGLDSALSEEAPASPSTRDAIQGMLSMANPPSSSSSSSSSSPLSISGGGEMMGLMKEKGGREGWMSGVKKSERKAVFQRPGKRPIKRPARHLSD------DESLDEQETLGTCFKDSDYVYPSLESDEEDHVSKSKMKRKRNWDDTPWSPKARVTPTLPKQERPVREGARVASVETGLAAAAAKLAQQEQQKTITKRKYTKKKTPQEKVHSTVAQLQHQPDSAPVSPPLPSEPPVDCIVE----ERRVEVYSASLLDHEYTAGPGPFSPGGP-RGSGAMAPGVFLTSRRPSLSPQNSSSYSPSAPSPGGLVTPTSAGACQGKRPKKGLATAKQRLGKILKIHRNGKLLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40034-1", "uniprot_id": "JHD1_YEAST", "id": "P40034-1", "name": "JmjC domain-containing histone demethylation protein 1", "aln": "------------------------------------MQDPNICQHCQLKDNPGALIWVKCDSCPQWVHVKCVPLKRIHYSNLTSSEVLSYPNSAKQIKSYRCPNHKEGEYLTAYALITQKGKRQRNKENPEDSHINKRYNFRKKKLLDYIALNEGESKRDKMNHPHKESFMKSFEKWKNGSNIINAADFAEKFDNIDVPYKIIDPLNSGVYVPNVGTDNGCLTVNYITEMIGEDYHVDVMDVQSQMNENWNLGSWNEYFTNTEPDRRDRIRNVISLEVSNIEG-LELERPTAVRQNDLVDKIWSFNGHLEKVNGEKAEENDPKPKVTKYILMSVKDAYTDFHLDFAGTSVYYNVISGQKKFLLFPPTQSNIDKYIEWSLKEDQNSVFLGDILEDGIAMELDAGDLFMIPAGYIHAVYTPVDSLVFGGNFLTIRDLETHLKIVEIEKLTKVPRRFTFPKFDQVMGKLCEYLALDKNKITSDVSD-GDLLSRTTNCAIQSLHAYVIKPEVKYKPLNFTSKKHLAKALADLIS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : *:* : : ::** * :*.* .** :: :.* :*. *:*** : . ::: :: : : . .: : . :: : . * : : :* .: .* : .. :.** :: . *: :* .::* : . :* : .:**:** * : : :**.: :*: . .*::: ******.*: . :* * **: . *:::*. : :* :*:* ** **.*:*:*****:**.****:*:*: *:* * *: ** :*: : ** ..:**.:*:** :: .:. *: ::**:*:**** ****.*.****** ::: :*: **** ... * **:*: : : ::: . : .: . . * : :. :::.:. * : : ::... : : : ** ", "identical_positions": 115, "similar_positions": 158, "identity": "9.98%" }, { "cls_id": "homologset.agr.MGI:2444343", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZZR5-1", "uniprot_id": "A0A8I5ZZR5_RAT", "id": "A0A8I5ZZR5-1", "name": "", "aln": "MAARERLFELWMLYCTKKDPDYLRLWLDNFVLSYEQFLDVDFEKLPT-----RVDDMPPGISLLPDNILQVLR--IQLLHCVQKTADGLEEQQQALSILLVKFFIILCRNLSNVEEIGTCSYINHVITMTTLYIQQLKSKKKEKEMADQTSIEEFVIHALAFCESLYDPYRNWRHRISGRILSSVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLK-CCLLHLFGAIVAGGQKNALQAISPATMEVLMR-----------------VLSDCDSWEE-----------------GDPEEVGRKRELTLKCLTQVVHILLTSSSDQRQVETSTILENYFKLLNSDHSALPKQGRSRRWES-----QFIALQIKMLNTITAMLDCADR--PVLQAVFLNSNCFEHLIRLLQNCKVFQGQLDCLAVSTIQALTAVMKNSPAAKEVFKERIGYMHMFEVLKSLGQPPQELLKELMNMAVEGDHTSVGILGISNVHPLLVLIQWLPELESHDLQIFISDWLKKICCINKQSRTTCVNANMGIKIIETLESHSSLHRTCAENLIAIHGSLGSQSVSSEELRRLLRLLRVDESECIHPYTIPVTRAILIMARKLSFESALQYFNLSHSMAGISVPPIQKWPGS-AFSFTAWFCLDQDPLSLGNANKGGKRKQLYSFFTGSGMGFEAFITHSGMLVVAVCTKREYATVMLPDHSFCDSLWHNITIVHVPGKRPFGQSLVYIYDNGQQKVSAPLRFPAMNEPFTSCCIGSAGQRTTTPPPSQIPDPPFSTPITPHRTSFGGILSSASWGGTVEKSK--------------LFTKLISAGTQDSEWGCPTSLEGQLGSVGIFHEALQPPQVKALYLAGPNCLSPWKCQDCDMAGLPSNLLLHYTGKACKNSICLDLSSN-CLHGRLTGNKVVNWDIKDIINCIGGLNVLFPLLEQISHVSEGQAC-----EAVSENTVPELITPIEQEGMGVASTKASESRLEKNLIATFILIVKHFIQRHPINQDNLIQSHGVATLGALLQKVPGTLMDVNVLMAIQLLIEQVS---LEKNTLLLQQMYQCLLFDFRIWNRGDFPFRIGHIQYLSTIIKDSRRVFRKKYGVQFLLDTLRIYYGHSSICNELSPDDIRTIRTSLYGLIKYFLCKGGSHEEIQSIIGYIAATNEEEQLFGILDILFSLLRTSPTRGQLFLLMFEPGNADILYALLLNQKYSDKLREIIFKVMEQMLKCTNVYERSKQRIRLREVG-----YSGIGLLLNEVPVNTSLIKNFVNQIINTDPVINFKDLLSIVYICHRAHVNVRVTLCRKILQILQSQPDAAYQISQQVGWQDTFVRLFLKANFENINSLNKHGK------TISVKEN-KNMSTEDVKRTFEKLDDEK----MTLADISSDHWSLEDSQSLNSNTPLFQE-------DSSEGELSFRSENQEEFWHSNTSHLSLDLSGIDASELSDSGSQMPDSSPSTPSPVESTKSFSVQSDKDRTITNEMGFSDDFSFLESQERCEEELFQLLTNILNYVLCKGLEKSDEDTWIERGQVFSALTKPGISSELIRPSDEVKLTLLQKMLEWAVTENRDAKSSPVTAEN--AFRLMLIIQDFLQSEGLVNSNMWTEKLLEDTTQLLDCLSVWYSENP-VWVKLSQIQIQLLLEFIGRGSLQVCAMASAKLNALLQTKVIANQDEACYILGKLEHILSRSIKEQT-EIYSFLIPLLRTLVSKIYELLFMNLHLPSLPFTNGSTSVFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMALYWKNCYEALMVNMHKRDREGGESKLKFQEYFVEPFNRKARQENLRYNNMIKQLTSQQLAASRHWKAIRLYLTCERGPWAEKKQNRIHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGVQHLQPSSDALLLEVVKQVRLSDVEEDRLELLEEDTAASALTDEKEEQDQKEKLVLTEDCELITVIDIIPGRLEVTTQHIYFHDNSIEKEDGQGFDFKWPHSQIREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKVYSRLLSLHSPNS-YGTRS-PQELFKASGLTQKWVNREITNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPTVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMENTYDVKELIPEFFYFPEFLENQNEFNLGQLQVSKELVNDVILPRWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAIQKQTKTEISTLNLFQHLPELKSFFIEGISDGIPLLKAIIPRNQSRSFMSQGSPELLITVSMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKAQRALSGPFAPGLEITSKLFAVSHDAKLLFSAGHWDNSIQVMSLTKGKLVSHNIRHIDIVTCLATDYCGIHLISGSRDTTCMIWQITQ--------------------------QGGTPVGLAPKPFQILYGHTDEILSVGISTELDMAVSGSRDGSVIIHTIQKGQYLRTLRPPCESSLFLTIPSLAISWEGHIVVYSSLEEKSTLKDKNLLHVFSINGKYLGSQVLSEQISDMCIVGEHIITGSLQGLLSVRELHSLKLSIAPLAMRLPIHCVSITKEHSHILVGLEDGKLIVVGVGKPAEMRSGQLSRKLWGSSKRLSQISAGETEYNTQDFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PYP2-1", "uniprot_id": "E9PYP2_MOUSE", "id": "E9PYP2-1", "name": "", "aln": "MAARERLFELWMLYCTKKDPDYLRLWLDNFVLSYEQFLDVDFEKLPT-----RVDDMPPGISLLPDNILQVLR--IQLLHCVQKTADGLEEQQQALSILLVKFFIILCRNLSNVEEIGTCSYINHVITMTTLYIQQLKSKKKEKEMADQTSIEEFVIHALAFCESLYDPYRNWRHRISGRILSSVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKDSLK-CCLLHLFGAIVAGGQRNALQAISPATMEVLMR-----------------VLSDCDSWEE-----------------GDPEEVGRKRELTLKCLTQVVHILLTSSSDQRQVETSTILENYFKLLNSDHSALPKQGRSRRWES-----QFIALQIKMLNTITSMLDCTDR--PVLQAIFLNSNCFEHLIRLLQNCKVFQGQLDCLAVSAIQALTAVMKSSPAAKEVFKERIGYMHMFEVLKSLGQPPQELLKELMNMAVEGDHTSVGILGISNVQPLLVLIQWLPELESHDLQIFVSDWLKKICCINKQSRTTCVNANMGIKIIEALESHSSLHRTCAENLIAIHGSLGSQSVSSEEIRRLLRLLRVDESECIHPYTIPVTRAVLTMARKLSFESALQYFNLSHSMAGISVPAIQRWPGS-AFSFTAWFCLDQDPLTLGSANKGGKRKQLYSFFTGSGMGFEAFITHSGVLVVAVCTKREYATVMLPDHSFCDSLWHNITIVHMPGKRPFGQSLVYIYDNGQQKVSAPLRFPAMNEPFTSCCIGSAGQRTTTPPPSQIPDPPFSTPITPHRTSFGGILSSASWGGTIEKSK--------------LFTKLISAGTQDSEWGCPTSLEGQLGSVIIFHEALQPPQVKALYLAGPNCLSPWKCQDCDMADLPSNILLHYTGKACKNSICLDLSAN-CLHGRLTGNKVVNWDIKDIINCIGGLNVLFPLLEQISHFSEGQTS-----EAMSENTVPELVTPSEQECMGLASTRASESRLEKNLIATFILIVKHFIQRHPINQDNLIQSHGVATLGALLQKVPGSQMDVNVLMAIQLLIEQVS---LEKNTLLLQQMYQCLLFDFRIWNRGDFPFQIGHIQYLSTIIKDSRRVFRKKYGVQFLLDTLRIYYGHGSTCNELSPDDIRTIRTSLYGLIKYFLCKGGTHEEIQSIIGYIAATNEEEQLFGILDILFSLLRTSPTRGQLFLLLFEPGNADILYALLLNQKYSDKLREIIFKVMEQMLKCTNVYERSKQRIRLREVG-----YSGIGLLLNEAPVNTSLIKNLVNQIINTDPVINFKDLLSVVYICHRTHVNVRVVLCRKILQILQSQPDAAYQISQQVGWQDTFVRLFLKANFENVNSLNKHGK------TVSMKEN-KNMSTEDVKRNFEKLDDEK----MMLADVSSDHWSLEDSQSLNSNTPLFQE-------DSSEGELSFKSENQEEFWHSNTSHLSLDLSGIDACELSDSGSQVPDSSPSTPSPVESTKSFSLQSDKERSITNEMGFSDDFSFLESQERCEEELFQLLTNILNYVMCKGLEKSDEDTWIERGQVFSALTKPGISSELLRPSDEVKLTLLQKMLEWAITENRDAKSSPVTAEN--AFRLMLIVQDFLQSEGLVNSNMWTEKLLEDATQLLDCLSVWYSENP-AWVKLSQIQTQLLLEFIGRGSLQVCAMASAKLNALLQTKVIENQDEACYILGKLEHILSRSIKEQT-EIYSFLIPLLRTLVSKIYELLFMNLHLPSLPFTNGSASFFEDFQEYCNSEEWQVYIEKYIVPYMKQYEAHTFYDGHENMALYWKNCYEALMVNMHKRDREGGESKLKFQEYFVEPFNRKARQENLRYNNMIKQLNSQQLAAVRRWKAIRLYLTCERGPWAEKKQNRIHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGVQHLQPSSDSLLLEVVKQVKLSDMEEDKLELLEEDMAARVNIDEKEEQNQKEKLVLTEDCELITVIDIIPGRLEVTTQHIYFHDNSVEKEDGLGFDFKWPHSQIREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPTG-YGTRS-PQELFKASGLTQKWVNREITNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPTVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNTYDVKELIPEFFYFPEFLENQNEFNLGHLQVSKELVNDVILPRWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAIQKQTKTEISTLNLFQHLTELKSFFIEGISDGIPLLKAIIPKNQSRSFMSQGSPELLITVSMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKAQRTISGPFAPGLEITSKLFVVSHDAKLLFSAGHWDNSIQVMSLTKGKIVSHNIRHIDIVTCLATDYCGIHLISGSRDTTCMIWQITQ--------------------------QGGTPVGLAPKPFQILYGHTDEILSVGISTELDMAVSGSRDGTVIIHTVQKGQYMRTLRLPCESSLFLTIPSLAISWEGHIVVYSSLEEKSVLKDKNLLHLFSINGKYLGSQVLSEQISDMCIIGEHIITGSLQGLLSIRELHSLKLSVTPLAMRLPIHCVSITKEYSHILVGLEDGKLIVVGVGKPAEMRSGQLSRKLWGSSKRLSQISAGETEYNTQDCK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZS30-2", "uniprot_id": "NBEL1_HUMAN", "id": "Q6ZS30-2", "name": "Neurobeachin-like protein 1", "aln": "MASRERLFELWMLYCTKKDPDYLKLWLDTFVSSYEQFLDVDFEKLPT-----RVDDMPPGISLLPDNILQVLR--IQLLQCVQKMADGLEEQQQALSILLVKFFIILCRNLSNVEEIGTCSYINYVITMTTLYIQQLKSKKKEKEMADQTCIEEFVIHALAFCESLYDPYRNWRHRISGRILSTVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLK-CCLLHLFGAIVAGGQRNALQAISPATMEVLMR-----------------VLADCDSWED-----------------GDPEEVGRKAELTLKCLTEVVHILLSSNSDQRQVETSTILENYFKLLNSDHSALPNQRRSRQWEN-----RFIALQIKMLNTITAMLDCTDR--PVLQAIFLNSNCFEHLIRLLQNCKVFQGQLDCLAISTIQALTAVMNKSPAAKEVFKERIGYTHMLEVLKSLGQPPLELLKELMNMAVEGDHTSVGILGISNVQPLLLLIQWLPELQSHDLQIFISDWLKRICCINRQSRTTCVNANMGIRIIETLDLHSSLHQTCAENLIAIHGSLGSQSVSSEEIRRLLRLLRVDESESVHPYVTPVTRAILTMARKLSLESALQYFNLSHSMAGISVPPIQKWPGS-AFSFSAWFCLDQDQLTLGIANKGGKRKQLYSFFTGSGMGFEAFITHSGMLVVAVCTKREYATVMLPDHSFCDSLWHNITVVHMPGKRPFGQSFVYIYDNGQQKVSAPLRFPAMNEPFTSCCIGSAGQRTTTPPPSQIPDPPFSSPITPHRTSFGGILSSASWGGTIEKSK--------------LITKLISAGTQDSEWGCPTSLEGQLGSVIIFYEPLQPPQVKALYLAGPNCLSPWKCQESDMADLPGNILLYYTAKACKNSICLDLSTN-CLHGRLTGNKVVNWDIKDIINCIGGLNVLFPLLEQISHFSEGQIP-----EEKNESTVPESVTPVEGDWLVWTSTKASESRLERNLVATFILIVKHFIQRHPINQGNLIHSHGVATLGALLQKVPSTLMDVNVLMAVQLLIEQVS---LEKNMQLLQQMYQYLLFDFRIWNRGDFPFRIGHIQYLSTIIKDSRRVFRKKYGVQFLLDTLRIYYGNGCKYNELSLDDIRTIRTSLYGLIKYFLCKGGSHEEIQSIMGYIAATNEEEQLFGILDVLFSLLRTSPTRGQLFLLLFEPGNADILYALLLNQKYSDRLREIIFKIMEQMLKCTNVYERSKQHIRLREVG-----YSGLGLLLNEALVNTSLIKNLTHQIINTDPVINFKDLLSVVYISHRAHINVRVAICRKVLQILQFQPDAAHQISQQVGWQDTLVRLFLKAKFENGNTLHKHSR------AVLMKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPE-------DSSVGELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQVFSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAEN--AFRLVLIIQDFLQSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESP-VWVKLSQIQIQLLLGFIGRGNLQVCAMASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQT-EIYSFLIPLVRTLVSKIYELLFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMALYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLATLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVLMEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRS-PQELFKASGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTSTLNLFQHLPELKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPELLITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQ--------------------------QGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9MRV7-1", "uniprot_id": "M9MRV7_DROME", "id": "M9MRV7-1", "name": "Neurobeachin-like protein 1", "aln": "MDNKKDIYNLWVQYTTKNDETHFRQFVARFVAIWRSQLQLDFQAENCPMWHEVQPDSGPHLGRLPDELLPAIGKFIIVARDVCETEGKLEEQAIEEVAILVDCLVIVCRHFDNILSIIKYEYKPNLIAILSRVFKQQMELPQS-----VPAISHLFSSFSAFLEVMYDPYLTWRSFVRG---QSADYSRLSYKPHSVHVEIVPFIYDCFQEEKLIRYAEIGESLLNILGAVICGSQLQLKVQKSLNSTSTLTNRNTNALTTSSLAPCSGDGLLDCDNLRNGMKAICPATVSITMSILRQWESANNLRRVALQCYALMVIVLQKSSPEERQIDLVTLVQLYCDALQELLATKHFDSGDANFDITSDADQDVAIDMAALSSTVAAVKFFVTGDAGVSEAVSDSNLLELLTNLPKLIKPWHISHSSSLCSTMEALAILARHSPQSASQLRQGERIERLFTSLQEYGSPTVELLDTCFMLGYDESEHFLLLP-----EVMLRLLNWVPTLQ-EREQLHVTSLVLKGCTDNYRTKTVACGSHIIKAVCGCLLTAESLAENCVQNLIKLIEELSKLSIVPAELKCIFSLLRQG-TKFPQFKQLQQTLVVIALQSLRGSNSCAEFFSIEQPTDGILVPDIRNWTISGSYGFIFHILVRFNQLKE----QSNSRRMLLTLQTASGSGFEVFVQPNGNVVVAALTRREYLTSSTATKTLMDGQWHYLTVAITPPKRPFSYSQINIYVDFVQKLSATLKVQAVNEPFTVCSIGAVVAPPQPGEVAKTGNMPRSSSQESGSSGYKGMLPSLLERTLSANVSNYFTLPMRTQTAFDPNVKNFPIGMQDTVFGEQTCLNGHLGGVLLADPTTS---LKTIFDAGAN-FSSIFSQDNDLLELNSRFVFCYAPGAIWHGTCQDLIPGGKYPGRINAQHCKIVKIQETINSIGGISAILPMLHRLITLDQTTDISIGSVSEESLSCAPTPSAEEFTDWEMLSSNSYTEWKMLQHPLASFLCLLRYLTHEHETNQEQLLSSECLAIVGTMLQRCPPSLFDVNALMATHLLMESLQGHKAEAGGQLLDALYAHIVFDFAIWSRLQFQITLGHAQYLSAMIKNDRKFFRKRYGVQFVLDVVRQYY---STPDSISDDDAKTIRATLFGIIKFYLQKDVNIKEVNSMITFLASVRQDVVLVEFLEMMTFYVRGKNCKDQMVLLLHEPQSANLLYNFFVDKSYSNEIQEAAIRFISGLLATSRVHQKYKQVLRLYDQTTEQSMFPGFFSFITPLSLSSTILFHLVDEMLGLQP--DYAGLIFLVYHVSSCDLPVKLEIAKRLLQTTFVKQQSTVAMAKQTGWQESIARLLIRKPITSSPPDEEKRRSFGINLDVLLEDNSNFLAQADLITFSEQEIGLAQLQQQQQEELSDSGLILNEIQASVTEAATVIESEIKELAESVSGAVVENANSLFSVIRQTTHDLQDTFESLTQGSSTDTADGSQTPSIQREESLSSDTSSQSPHGPPKKSDSLESTSAFDFVADGDVDTEEQLVYLVSNTLFNIFWRGIPNDHPQCWQERGQVLGCINLLALNNELITSHLSLRLRILEMAVQASLFDLSEHGSQTLVNQENASHILRMVYELVVLGSNEDESKKCSTKLLDGVLALLDALMIFQQGSSDDWSDMIRLCLGLLLKCSHHPNPGIVAMATAKLHAILQSRSTEDPAELSYLLYSINRALDNAIEVGNPEEYSFLMPVMKALLEKCRVAFNLDSTLPDLPSTSSGPVFFNDFQMYSTSKKWRNFIERMVKPLYDRYQRDIELHLWEPINRFWAECYEACKAASKQRATNQAENRRLFQQKIYMPWKVRQVEEMQRLQAAALQHKTIDSHIRKRWKTAKRFLYGPRGPWYTGEVDEEFWKLSQHENVARMRLKLEPQLYPNKHENAANLRDNATSAYDTKEISEFDSTIKNAVVRDFLADDESSQLEEELRQLIDT-QAQQDVALEKLVMSQDCELITLMTKVKGRIEVNQSVFTFVDLSPPTEDGSKYDFRFSTNKIREVHLRKYNLRRSALEIFLVDQTSYFLNFTTKTRNKVFTKIVGLPLPNILYGSGRSPAELLRASGLTQRWINREISNFEYLMYLNTIAGRSYNDLSQYPVFPWILADYTSDVLDLTDPKSFRDLSKPIGCINPKNEAEVRGKYDSFEDPSGAIPKFHYGTHYSNSAGVLHYLLRVEPFTSLHIDLQSGRFDVADRQFHSIPQTWKLLMDNPNDVKELIPEFFYFPEFLKNMNKFDLGHLQITKEKVDDVILPAWATTPEEFIAIHRRALESEYVSQHLHHWIDLIFGYKQKGPKAAEALNVFYYCSYEGAVDLDKITNPVEREAVEGMINNFGQVPSQLLREPHPRRLTQDETALKLVRAELRRPDLTQFLDKVVQYYCELSTPKDPIVYLSPPRSPPRSFLQLS-PDVLVSISKSTILGCNSWLSFDKDQG--FLLEIDATTANLKNRKRIFGPFHSSQQPHSQLFAVSTDGKLLYAGGIWDNSLRVYNLNKGKAVASVTRHLDIITCIALDNCGSYLVTGSRDCTCIVWSIQTNQQGGGSTNNIPVHALTGQSHLQAITQLNTQNSYSPKPLTVLYGHDDAISSVAIYTELDLVVSGSLDGTVNVYTLQEGQFVRTLKPIGCTESCVQISFVTLSYHGHIAFSALDDTS------HSVHVYSINGCSLGSKYVSGRVTGLASASDYLVVADDAGDITMSRLHGLKP-VFDIPLHVPIQTVVVTPGNTHILAPLRDGRLAVIAVQLPSGGNKKHSVLNV-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: :::**: * **:* ::: :: ** :.. *::**: * * :. ***::* .: * : : * : . **** :**. ::*:**::.*: .* . .* :*:: : ::* . :. ..*..:. ** * :**** .** : * .:.: ** .*** *: **:***:*:****.: :: : .**:::**::.*.* : * : ..* . * ***. .: : *.... .::*:* : :* :* .*..::**:: *::: * . *:. :: : . .:: : :*::: *.: .: :. . :. . :** :* * .* : * :: . .. *:::**: : . ** : . ::: ::: *:. *.*. ***. : :. : .. : : . :* *::*:* *: . *:.::. : : * * :::*.. .::: : * .** ..*.:*** : .*.. *: . *:: :: *** . :: : * .:: : . :*. ::*.:.:. ** ** *:.*. * ::.* : : : *. :...*: * :: *.** ***.*: .* :***. *:*** * . ::: *. ** :*:. * ****. * : ** : **:**.*:. *:***** *.**:. . . :: : * *:. . :.: *:*.* : . .* :. * **: :* *.*:*:**.* : . . :*::: **.* :*. .*: *: * ..::: *: * :. * ** .. **:..:: .*:: **.***:..::*:*.:: ..: . . . .* : : :*. :* :: :: :*:*: ::::: :.* ** :*: *. :* :*::**: * : :***.*** :**:*.:. * . **: :* ::*** **.* :* : :** ****::**:.*:.***:*****:**.:* ** . :.:* ** :***::*:*:**::* *. . :*::*:: ::*:..:: *. :*::: :* . :.*:.**:.** .*::** :::::.**:.::* ::.:. :* :.*::: ** :** : :.*: ::. :.:::: ::..:::. :* :: .*: :** .: *:: :.:::** : ::: :::*.***:::.**::: : . . .:: : : :::* : :: * :: . ::*.. *:: :: :::. . * :* * : .::. .. :... .*. :..: . :*:.. . . ..:.* .* . . . . . * . :.: **:*. *::: * :: :*: :.. : * *****:..:. .:..**: . .::* :*: :: :: : : :..:. :: :. * :: : .: ... :*: : ***:. *:*.* : . .. * .: :: *** : . : ***:***:::**:: : * .*:* .::: *..:*: . * ****:*::::*:.* : :: **.** *.... .*:*** *..*::*: :**: : * .:*: . . * : :* :**** . ::* : .*.: **: : *:: : :* * : * .: : ::**: : :* **** : : .***:: ** :****** *: :.**:*: **** : . . : : : * . : :*. . **: : ::: ****: :******:: : **:*:. . : * * * .*** :**::. .:***:***:*********** ***:.*****..:.***::::::.* *. **: * **::******:*:****:**:**: :**:***:****:********* ****: ***.:* ********* :* ** :* **:.**** *:* **************:***:******:***:******* ********* **: **:*. ****************:* *:*:**:**::** *:***** **.:.*:** **:******** ***.**********:** *.****************** :*: **:*:*********.*.***:**** **: :*: * .: : :* *.* :: .:: * : *:: *:. ***:. . *::*:::* . ::* :.**.:*:: . * : * *.:* * :: : *.* .. : *:**.** *.***::.* ****::* .*.*** :: **:**:**:* * ** :*::**** **::*.* * .. . :.**: :**** : : **.* ****:.**** **:* ::*:*:**::***: :. : *. :::*:.***.. : : . : :*::**** ***: :. :::.:. .::::... * ::: **.*: : :.:::**: * :* :***. *.**:* *:.* *: .. : :. ", "identical_positions": 837, "similar_positions": 979, "identity": "29.72%" }, { "cls_id": "homologset.agr.MGI:2444345", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGG9-1", "uniprot_id": "ACNT2_MOUSE", "id": "Q8BGG9-1", "name": "Acyl-coenzyme A amino acid N-acyltransferase 2", "aln": "MMIQLIATPSNALVDEPVSIRATGLPPSQIVTIKATVKDENDNVFQSQAFYKTNEAGEVDLEKTPALGGDYVGVHPMGLFFSLKPKKAFHRLMKKDVMNSPLCICLDLYDSVNWLETVRIPSKASQRVQRWFVGPGVKREQIQEGRVRGALFLPPGKGPFPGIIDLFGLIGGLVEFRASLLASHGFAVLALAYFAYEDLPEKPQEVDLEYFEEAANFLLSHPKIQQPGIGVISTSKGAEIGLAMACYLKQVIATVCINGPTTITIFPLRYQDLVMTPIHPALERIQVHDSGALLFRYTTQYLHNKLNSQNILPVEKAQGKILFIVGENDECLDSKLHAQKAMDRLQRHGRSSGRMLAYPGAGHLIEPPYSPVCFVAWFPVLGQPMCFGGDLMAHAAAQEHSWREIQKFFRKHLLQSGSKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FVR5-1", "uniprot_id": "ACNT2_RAT", "id": "Q5FVR5-1", "name": "Acyl-coenzyme A amino acid N-acyltransferase 2", "aln": "-MLQLIATPSNALADEPVSIRAIGLPPSQIVTITATVKDEKENLFQSKAFYKANEAGEVDLEQASALGGDYVGVHPMGLFCCLKPKRAFQRLIKKDVMNSPLCICLDLYDSVCWLETVRIPPKASQIVHRWFAGPGVKREQIREGRVRGALFLPPGKGPFPGIIDLFGSIGGLVEFRASLLASRGFAVLALAYFAYEDLPKVLLEEDLDYFEEAANFLLAHPKIQQPGIGVISVSKGAEIGLAMACYLKQVVATVCINGPSAIFDFPLKYRDLVVTPMRLAFEKIQFHGSGAACFRHCWD-PQNMLNPPKILPVEKAQGKILFIVGENDQCLASKLHAQRAMDRLRSHGRSSGRMLAYPGAGHLIEPPYSPFCFACWDSVLGKPMLWGGDPIAHAAAQVHSWREIQKFFRQHLLQSGGKL", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:**********.******** **********.******::*:***:****:*********::.*************** .****:**:**:******************* ********.**** *:***.*********:************************* **************:****************: * **:**********:*************.*****************:********::* ***:*:***:**:: *:*:**.*.*** **: : :* **. :*******************:** ******:*****: ************************.**..* .***:** :*** :****** ***********:******.**", "identical_positions": 340, "similar_positions": 53, "identity": "80.95%" }, { "cls_id": "homologset.agr.MGI:2444350", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ACP1-1", "uniprot_id": "TT39A_MOUSE", "id": "A2ACP1-1", "name": "Tetratricopeptide repeat protein 39A", "aln": "--------------------------------------------MGQKGHKDSLYDCKGSPVSSLHEALDQCMTALDLFLTNQFSEALSYLKP----RTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQSLCQRHRRKSSMTDSFSNLVHRPTIDQFTEEEIHAEVCYAECLLQRAALTFLQ--------------------------------------------DENMVSFIKGG----------------IKVRNSYQTYKELDSLVQS------------------------------------------SQYSKGESHRHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGATGHSFRAVLCVMLLLCYHT-----------FLTFVLGTGNVNIEEAEKLLKPYLNR---------------YPKGAIFLFFAGRIEAIKGNIDAAVRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMAYFYADLLSKENSWSKATYIYMK-AAYLS---------MFGKEDYKPFGDNEVELFRAVPGL-KLKIAGKSLPTEKFAIRKSRRYLSPNP---ISLPIPALEMMYIWNGYAVIGKQPTLTDGMLEVITKAEEMLAMGPENEYSADDDCLVKLLKGLCLKYLGRIQEAEENFRS------ISANEKKIKY-----DHYLIPNALLELALLFMEQGRNE---EAIKLLESAKQNYKNYSMESRTHFRIQAATLQARSSLEDGNRSLVSSVSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7F7D5-1", "uniprot_id": "F7F7D5_RAT", "id": "F7F7D5-1", "name": "", "aln": "-----------------------------------------MAFLTTWKRAASRKRDRRSPVSSLHEALDQCMTALDLFLTNQFSEALSYLKP----RTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQSLCQRHRRKSSVTDSFSSLVHRPTIDQFTEEEIHAEVCYAECLLQRAALTFLQ--------------------------------------------DENMVSFIKGG----------------IKVRNSYQTYKELDSLVQS------------------------------------------SQYSKGESHRHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGATGHSFRAVLCVMLLLCYHT-----------FLTFVLGTGNVNIEEAEKLLKPYLNR---------------YPKGAIFLFFAGRIEAIKGNIDAAVRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMAYFYADLLSKENSWSKATYIYMK-AAYLS---------MFGKEDYKPFGDDEVELFRAVPGL-KLKIAGKSLPTEKFAIRKSRRYLSPNP---ISLPIPALEMMYIWNGYAVIGKQQKLTDGMLAVITKAEEMLAMGPENEYSADDDCLVKLLKGLCLKYLGRIQEAEENFRS------ISANEKKIKY-----DHYLIPNALLELALLFMEQGRNE---EAIKLLDSAKQNYKNYSMESRTHFRIQAATLQARSSLGDGSRSPVSSVSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SRH9-1", "uniprot_id": "TT39A_HUMAN", "id": "Q5SRH9-1", "name": "Tetratricopeptide repeat protein 39A", "aln": "--------------------------------------------MGQKGHKDSLYPCGGTPESSLHEALDQCMTALDLFLTNQFSEALSYLKP----RTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLVNRPTLGQFTEEEIHAEVCYAECLLQRAALTFLQGSSHGGAVRPRALHDPSHACSCPPGPGRQ---------HLFLLQDENMVSFIKGG----------------IKVRNSYQTYKELDSLVQS------------------------------------------SQYCKGENHPHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVMLLLCYHT-----------FLTFVLGTGNVNIEEAEKLLKPYLNR---------------YPKGAIFLFFAGRIEVIKGNIDAAIRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMK-AAYLS---------MFGKEDHKPFGDDEVELFRAVPGL-KLKIAGKSLPTEKFAIRKSRRYFSSNP---ISLPVPALEMMYIWNGYAVIGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRS------ISANEKKIKY-----DHYLIPNALLELALLLMEQDRNE---EAIKLLESAKQNYKNYSMESRTHFRIQAATLQAKSSLENSSRSMVSSVSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BE96-1", "uniprot_id": "A0A8M2BE96_DANRE", "id": "A0A8M2BE96-1", "name": "", "aln": "MCVCCSQREAAVLLTGAKAKACSYTHCEVLCVSFSCLLLSSISLYQMKMSREAETLSNGSEKPDLSADLQDCMAALDLFLQNQFDESLSRLRS----RNKDSMYHALTYATILEMQAMMTFNPEDIFAAGNTMKEAQAVCQRYRKKS----SFNS-------KNFTEEELHAEVCYAECLLQRAALTFLQ--------------------------------------------DENMISFIKGG----------------MKVRNSYQIYKELHTILKS------------------------------------------SGYVQGDNHGHFEGGVKLGIGAFNLMLSLLPTRTLRLLEFVGFSGNKEFGLEQLQEGCSEHTFRSFLCNMLLLCYHT-----------FMSFILGTGEGDVEDAEKLLQPYLKK---------------YPKGSIFLFFAGRIEEIKGNLDAAIKRFEECCEAQQDWKQFHHMCYWELMWCFTYKRHWKMAYFYADLLSKENNWSKATYAYMK-GAYLS---------MLSREECQPFGENEVALFRQVPSL-KQKIAGKSLPTEKFAIRKARRYNTDNV---IPLPAPPLEMMYIWNGYTVIGKHKDLTEGMLKTLDEAQQTLEQTPRTEFTTDDQCVVSLLKGLCLKHLGYKEEAEHYFTL------VLCNESLIKY-----DHYLVPNALLEHGLLCLEEGRID---EAIKLLEAAKQNYKNYSMESRTHFRIQAALHKARGTAVNGYHSSPSSP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1A5Y5-1", "uniprot_id": "TT39A_DANRE", "id": "A1A5Y5-1", "name": "Tetratricopeptide repeat protein 39A", "aln": "-----------------------------------------------MSTGKNAPVTENSRQMSLQACLDECMEALDLFLNNHFNESLDKLRP----RSKESMYHALIYATVLEMQAMMTFQQDDIVHAGNTMKSAQEVCQRFRKKSGGLGSRGAN------DDLSEEQIHAEVCYAECLLHRAALTFLQ--------------------------------------------DENMVSFIKGG----------------IKVRNSYLIYKELHAFIQS------------------------------------------DATFKGPNHKHLEGGVSFGIGAFNLTLSLFPARILKLLEFAGFSGDKEFGISQLYTGATSHTLRSMLCALLLLCFYT-----------FLSFILGTGEGEVEEAERLLKPFRLR---------------YPRGAIFLFFAGRAEEIKGNIDEAVALFEDGCKAQQVWKQFHHMCYWELMWCFTFKRYWKMAYFYADLLSQESRWSKAMYVYMK-AAYLS---------MLPDSESRPFGDNEVDLFRQVPTY-KQKIAGKSPPTEKFAIRKARRYKASNP---VRLPVPVLEMMYMWNGFSMISKQPELTEGMMETLLEAERTLRASPDNEYTVDDTCLIQLLKGLCLKNQGQMQAAEDCFNQ------VYISEKKLKF-----DHYLVPNALLEMSLLFIDTGRKE---QAIKLLQKAKNNYKVYSMESRTQFRVHAALTKLKADVSD--QEEITAL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36114-1", "uniprot_id": "YKR18_YEAST", "id": "P36114-1", "name": "IML2-like protein YKR018C", "aln": "-------------------------------------MFKVFGFGAKEEIPELSQEEKTKAILKQAHDFEQALRAMDYVLDDNADEGLALLDESDAKEASDQTINALARGVIEFLEATLGFEAEEMKKASATLAKAEALSLKSRERAQKIGLKSS-------SLYPPGTVYAVTYTESCLLHALLMIFSESMMEAAKAILKLRKSYYMLQEILETIKAANKAKKLKITSGSEDKESTPATFITGGDAFNSVDIPYELTPEEQKDKDLLQFAEQIHSMRTERLSGAHIGNSPAINRLRGELGLQAMEDLPEEEITDHKVLSDDIDLSQATIDEFVHSGVNLCFGILQVVISLLPPAIGAVLSVVGFRGSREEGLRLVWKATKQRNVHGCIGLLALMFYYDGPFQFTDDDFDIPAAVKDSSNSEDSEDEEMDGPTLLHPGKILEDALLQSRALFPNSALWLLNEARMLSGKGRLEEAVALMDSIDVSKIRMRQVKSLMIFDRAITLIHLHQYDRAAEDILSLLDISDWSHAFYTYFAGCCYLENWRMCEMGLMKSDKKDEYQKKAEELIFTSVNLLGKKTFKSKNLPLDRFILRKVEQFKAKKEELGVENPLDGIATSPVHEIAYFYNGYNRMSEEHLELTKKMLTEYRNPAIEALDSDQELIKDLLVSLTLRRLGHIQEGCDILDEKVLPKFFSIQNGKVKYIKKTEDPWAYPTALYERALFTWKLEGMDGLPESKEWLLRAQGYADDYELSTRVGMKIKAAIDRVDHSL-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :::.: *:* .* :: .*.* * . .:. ::* ..: ::* : *: ::: *. : .*: :. : *.:: . . ::* . .***: : * : :.. :**.** * :: :::.:: . :. . ....**.: .* ::: :*::*. :*...** *.:: *: : . . :..:. : : *: :: : : : .:.: : .: *.: * : :*..:::*: .* **.:: *: ::. :: :*.: : :: : . :. : * . . **:* * *: .**. * .. . . * :* * * .: .*. * ::* :** .:: : : : * : : : . . ::: : : . *: : .** .* *: * : . . : . .: :*: * : *.** * .*: . : :: : * *: . *.:.:*. ::::** : ", "identical_positions": 80, "similar_positions": 211, "identity": "10.23%" }, { "cls_id": "homologset.agr.MGI:2444354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADE4-1", "uniprot_id": "D4ADE4_RAT", "id": "D4ADE4-1", "name": "AT-rich interactive domain-containing protein 4A", "aln": "MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGP---LRVGAIVETRTSDG-SIQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETLDQLPLTNPEHFGTPVIAKKTNRGRRSSLPITEDEKEEESSGEEEEDKRRLNDEFLGRVVNVSPTAQSTECYPALVVSPSCNDDVTVK-KDQCLVRSFIDSKFYSVARKDIKELDLLSLPESELCTKPGLRRASVFLKARIVPDNWKMDISEILESSSSDDEECPAEEHEEEKEKEAKKEEEELPEEELDPEERDNFLQQLYKFMEDRGTPINKAPVLGYKDLNLFKLFRLVYHQGGCDSIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTIHHHEPK---------------------------VKEEKKDFEESMDEALKVAQEMPLMDVKS-----EPEENID-SNSESDREDTELKSPRGRRK-IVREANCIKKELEEEKIEDKLIGDDIDNKDA---------------------------------------------DDDDYDIAEKKETELLLGRKTTPKHKEKKIKQQEDSERDSEE-------------------------------------EEEKSQEREETESRCDSEGED----------DE-------DDTEPCLTGTKVKVKYGRGK----TQKIYEASIKSTEMDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKVKNKED---------------------------------SEKDEKRD-------EERQKSKRGRPPLKST--------------------------------FSSNMPYSLSKTSNSEGKSDSCSSDSEAEDQLEKSSVSEELSPDIKEELEKSENVHDDKLAEENPKT-VHISNEND--------RTQAQPSEPLTVEAGDSDQIVHIFGDKVEQAEELKKQVEK------------SPKAKGR-----------------------RNKTKDLSLELIKISPFSQ------EEAGSEARGDTHSLEFSSLE----------CKNFS-STEDDVDQYEKEKKLKRKILGQHSP--------------------EKKLRLENGVEMTTGLSQERSDDSAVAEGVKGVHVEQRFEAEGE---GMPSLIAEPDQGIQEPTGV----------------------KPDSPA-EEPAHTPLKEEEDVMPLIGPETLVCHEVDLDDLDEKEKPSIEDVVIEGSE---SNSLGS-------------VPPALPPVAQQNFSVASPLTLSQDESRSIKSES----------------------------DITIEVDSIAEESQEGLCERESANGFEASVTSGACGMIVHERESREKGQKRPSDANSGLMAKKQKRTPKRTSAAAKSEKNGAGQSSDSEDLPAMDSSSNCTPVKRLSLPKPQKLPRSPARISPHIKDGEKEKHREKHPNSSPRTYKWSFQLSKDELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKR--------------LKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VPQ2-1", "uniprot_id": "ARI4A_MOUSE", "id": "F8VPQ2-1", "name": "AT-rich interactive domain-containing protein 4A", "aln": "MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGP---LRVGAIVETRTSDG-SIQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETLDQLPLTNPEHFGTPVIAKKTNRGRRSSLPITEDEKEEESSEEEDEDKRRLNDELLGKVVSVASTAESTGWYPALVVSPSCNDDVTVK-KDQCLVRSFIDSKFYSIARKDIKELDILTLPESELCARPGLRRASVFLKGRIVPDNWKMDISEILESSSSDDEECPAEEHEEEKEKEAKKEEEELPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCGNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTIHHHEPK---------------------------VKEEKKDFEDSMDEALKEAPEMPLLDVKS-----EPEENTD-SNSESDREDTELKSPRGRRK-IVRDANCIKKEIEEEKIEDKFLRDDLENKDAGD-------------------------------------------DDDDGDPAAKREHELLFGRKSTPKNKEKKIKKPEDSERDSDE-------------------------------------EEEKSQEREETESRCDSEGED----------EE-------DDTEPCLTGTKVKVKYGRGK----TQKIYEASIKSTEMDDGEILYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKVKNKED---------------------------------SEKDEKRD-------EERQKSKRGRPPLKST--------------------------------FSPNMPYSLSKTSNSEGKSDSCSSDSEADDQLEKSSGGEDLSPDVKEELEKNENAHDDKLDEENPKI-VHISKEND--------RTQAQPSDTLTVEAGDSDQIVHIFGDKVDQVEEFKKQVEK------------SPKGKGR-----------------------RSKTKDLSLELIKISPFGQ------EEAGSEAHGDVHSLEFSSLE----------CKNFS-STEDDIDPYEKEKKLKRKILGQQSP--------------------EKKLRLDNGMEMTTGVSQERSDDGAGAEGMKGAHVEQHFETEGE---GMPSLTAEPDQGLQELTSE----------------------KSDSPAEEEPVHTPLKEEEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVVVEGSE---SNSLAS-------------VPPALPPVAQHNFSVASPLTLSQDESRSIKSES----------------------------DITIEVDSIAEESQEGLCERESANGFEASVASGACSIIAHERESREKGQKRPSDGNSGLIAKKQKRTPKRTSAAAKTEKNGAGQSSDSEDLPAMDSSSNCTPVKRLTLPKSQKLPRSPARTSPHIKDAEKEKHREKHPNSSPRTYKWSFQLN--ELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKR--------------LKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29374-1", "uniprot_id": "ARI4A_HUMAN", "id": "P29374-1", "name": "AT-rich interactive domain-containing protein 4A", "aln": "MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGP---LRVGAIVETRTSDG-SFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETLDQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVSVVSATERTEWYPALVISPSCNDDITVK-KDQCLVRSFIDSKFYSIARKDIKEVDILNLPESELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEEEVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPK---------------------------VKEEKKDLEESMEEALKLDQEMPLTEVKS-----EPEENID-SNSESEREEIELKSPRGRRR-IARDVNSIKKEIEEEKTEDKLKDNDTENKDV----------------------------------------------DDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDKDSDE-------------------------------------EEEKSQEREETESKCDSEGEE----------DE-------EDMEPCLTGTKVKVKYGRGK----TQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKED---------------------------------SEKDEKRD-------EERQKSKRGRPPLKST--------------------------------LSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELS--LKDELEKNENLNDDKLDEENPKISAHILKEND--------RTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEK------------SPKGKGR-----------------------RSKTKDLSLEIIKISSFGQ------NEAGSEPHIEAHSLELSSLD----------NKNFSSATEDEIDQCVKEKKLKRKILGQSSP--------------------EKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNFEQHFERENE---GMPSLIAESNQCIQQLTSE----------------------RFDSPA-EETVNIPLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSE---SNSLVS-------------IPPALPPVVQHNFSVASPLTLSQDESRSVKSES----------------------------DITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSSKCTPVKHLNVSKPQKLARSPARISPHIKDGEKDKHREKHPNSSPRTYKWSFQLN--ELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKR--------------LKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B539-1", "uniprot_id": "A0A8M2B539_DANRE", "id": "A0A8M2B539-1", "name": "AT-rich interactive domain-containing protein 4A", "aln": "MKVADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRMVKVKVVLKGDSTSQVVQDDQVKGP---LRVGSTVEVKSPEG-GLSEAVISKLTDASWYTVVFDDGDEKTLRRTSLCLKGERHFAESETLDQLPLTNPEHFGTPVIGKKTNRGRRSSQAVAEDEKESSSSEDDDDDKRRLNDDLLGKVACVQSEPD-DSWLCVLVISPSCNDDLTVK-KDQCLVRSFADSKFHTVARKDVKEVNIDTLSKPEYSLRKGCEAAKLFLQNRQIPDRWKVDLSEILESSSSDEDDEDEDGEGKEGEEEEKEPEPEEPDDEPDPEERDHFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVHIHGGCDNIESGSIWKQIYMDLGIPVLNSAASYNVKTAYRKYLYGFEEYCRSAQIQFRTVHHNEPRP-------------------------DVQPEVQSIKSVTKESENNDEMMQQVTAEPGTSEDKPAADADESDAESEKGRKDVCSPRGRRRCLTTPVKVEMEPLKQEKIKEEKKKEDTQSVGE----------------------------------------------NSGEEPKEKSDGEIPGKRRSRRHEESDKDSEEDDDDNDDEE-------------------------------------QDDDDEDDEEEEEDDDDEEEDYFERSRLRERDEREEGDGCEDSEHSLAGTKVRVKYGKGK----TQKIYEANIKNTETDDGEVLYLVHYYGWNVRYDEWVKADRIIWPVDKGGTKKKQKKKVKNKED---------------------------------EEKEKEED-------KTKVVVRRGRPPLKSTP-----------------------------PGTSRKTPSSEGRSSSKNSRPTDASALPNGDGTPRRRTRRTSGMYDSDRGSNDSGNSSDDSEGEKSPEKKQEWTERTDPPPIAKQEAADDLPEESTTQEPAQTEPELPSSPQEMPNFNESESKPEEDSSMPPTESDVGSPKMTAK-----------------------KPRLKEPGSETPTQTPAAANHHAETEEPSTPPRPVKKSQETPHSSPVERIKLVETAGSDTDSATEDIDPPERTSAAKRKINEQRTP--------------------EKKIRLDRKEEPKTPSPVKTSPLEKKPESEKRTEIVQKPEEPPNPTLSSPSKEVEIKSEMPSLTREV-------------------HLKLEAPCPDLEDPTTVAN-EEMMPQIGPEALVCHEVDLDDPEEKDKPSSEELPIMKEEKVLPQPLESP-----------DHLHVLPAVGPPRLFSPS-SAPSPDESHSTKSES----------------------------DATIEVDSVAE-SQEGLGENESTHSFDASASSSNSSISLQDRDGKDRGQKRLLDCTTVSSSKKQKRSQKRSSVGCKTEKNGAGHSSDSEDQSVMDGSNKLTPVKHSILPKNQKLSRSPGLGSPSNKYIEKDKHKEKQSVPSPRTYKWSCQLT--ELDNMSSAERISFLQDKLQEIRKYYMSLKSEVASIDRRRKR--------------LKKKEREVSHTTASTSSGSSDTGMSPSSASPTQNTVAVECR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWP5-1", "uniprot_id": "Q9VWP5_DROME", "id": "Q9VWP5-1", "name": "", "aln": "MQQMDDPPSLPVGTEVSAKYKGAFCEAKVSKVVRNIKVKVAYKQGLGSGIVSDDAIKAPTGQLRVGAVVEVRHPDRKELVEATITKIQDCSQYTVVFDDGDITTLRRTALCLKSGRHFNESETLDQLPLTHPEHFGNPVVGGRRGR-RRGHLNEDSSEDDDESDAKEVVNEKEENIGKVVCVETESKKKDKEKWFPALVVAPTAQATVRIRVKDEYLVRSFKDGRYYTVPKKEATEFTREVASKQ---DVPAVQAALEFLDSSVLPAHWDRDSLFGLTNISSDDEGEIDSDSSDDEPHE----------------EKDRFVAQLYKYMDDRGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNRVTSQNQWKLIAMRLGFTPCTVSVMNLVKQAYKKFLQPYGDFHRKLGCSMLMTSRNSNRSKGRSLVRANSVASPKPMETMKTETISKLAQPNQTNVVASTSSSAAAASVAASSTPARAVSTASQSAAEESGNTSESSVVVEPPKKQRKGSAASSQQGKVKSLVEKYEEKSTAVQATSSGTVAGSGASASAAAMPTTSAAASTATNLSSATSGGSATIATTAMNKDAESDLPLAKIKAAAVAAASTRHSMEKETNISSGSSASASSKANSAEMQRSRDASPSVAAPPSAGASTSGAAATAQTASNKKEKHQRSKQADKEKDKDKEEKQASSGKRKKEKISVEKIDTGDFVVGIGDKLKVNYHEKKSPSSHGSTYEAKVIEISVQRGVPMYLVHYTGWNNRYDEWVPRERIAENLTKGSKQKTRTISTSSANSGSGGGGGGGGGGGGGGGGGGGSLLVQGSQPPGVSDKQPGKDGCSKMSPSSGNSTGPGAPSLSGSLGGASSTPSLLSTVVKTPPTGGAKRGRGRSDSMPPRSTTPSSVVAHSGRTKSPAASQPQLQQQMKKRPTRVVPGTTTPRRVSDASMASESDSDSDEPVRRPKRQSAKDKPQAG---KAQPPGKGRLASSASSTAPAAHPSDDSEEDEEEEEPSAARAASSKQQQQQASSLRGSRAGGNRAMSSGAASAKGRDYDLSEIRSELKGFQPKLLTNAASNEERKDLAKKEPSDEPALQDIKKEPKLESSAKSSSTELSSETESYADEDSQSSDYRKQLKGSGAGKKEPTASPSKLHHEPVTKRELAVKEEPLKIEPKTEPKEEETKSKPFLSGADIKPTALIAPARFGNTSAAQAASSSGSSSTTAKYTSVIVEKPLTIGGKKSVEQHVPKKAELLKKQSGGAGGTAASSSAASQESKKFAEPVASLKVEMPAACSPSSSSSSSSSFCSTGSAVSSSSATRSLPDMSKLEISSGTVPGATPGAAALQPSNVAQVSSSGAAKESKYSSSGGAAAGSGISMRKLLSSDVYEFKDTEPFEFEKRISPMASVGGTVAAAATAAGAMAAAGAASVITTMVPTPGASGSGVAASASTSAPVVVGSAARKQALKASAIQHILEHQSPAAGRERGGYGGMTSSISLLTAPKLKKRGSPLKEAALCMEKAKTYKLDKDQVQQPVEQKTQQLIQPTLGPVESYGAGSPEAMSNLSTPTTSSGHAQLSASSTYSQLTPHHATPFDALRKSPSFNLNITALNEELAQTVQETTRALTDALQPPSTPVPPTVSASGSTPTAVTPVITAMPTAGTAGLSCPSTPPTGANPVLASPKLSTPPQAINASKQPPASHIVGSPFIETRNVFELSTSNEGSGYSSGESKDNKFEKLENVKILLAGAVGPFDLDAGSYEQKTSSIADKVLKAISQKKEEVENNKGKPPVEPAAAAKTPGREDVVPSPTAKLDLCSSAIKLDTLKLLSEPLKIQTGPLLGELYRPGPATSSPETKSILESSLPAKNSELSETIQKLECAIQQRKTPVGGALSLASSTAGTPPTAHTPNSTATAGAGFSDESMDSTDSEQRLVIEDVIAEEHTTTTTTGEQKSPGSQQEEGQTNTATMATAVTAETEGTSSSTPTPPVPAPVKLELGAKAMPGIQAPIPLKPAEGSSFAGKLTGVVQPPPLAKLQQQEELGQAQGQSKSISSFGIPIVLPEIPASVVVATPALMVASAATVMRHSPGSTPNSQAPVLISPKTFLTAPKVGEVGGLLLKAYTGVSGAVGAAPAGSVIASAGGGGTPTVISNFPQQQQQASVLQASSEMPANYVLDAEMAEPSNSSAPVVARPFVMHAVGKELFNVVAPAASSPLISDPHNESINLLCEETIPGSPAPNYGGTDQLPTAVNSALAIVGITPLPPDTPPPVPVAAIQQQQQHQLQSGQQQQAAKTGEVNPSGPNSSPDSASQDESGEEAKKNAGLEHEDSTGLGALNKRKRNRKPLPMSAQTAAAVAAQLQSLGKRRRQVSGMRNQKTTTTAAGSDTDDNSDNIAPNAGQQQQQPRQSARQHMMPQSNAQQQQQQQLLQQQQTQLPQGIQSTNSSGVRPCPYNFLVELDPALSSDECITILRKQIQDLRKAYNTIKGELAVIDRRRKKLRRREREKKQQQLQSQQQGKICA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *:*. *.***:*****:*******:..* * :**** * . : :*.** :*.* ****: **.: .: : ** *:*: *.* ********* *****:****. *** ***********:*****.**:. : .* **. ..*.:..*. .: :::. * : * : .**::*:.: : :: **: ***** *.:::::.:*: .*. .: . . * **. :* .*. * * . ***:: . .: .* *:*.*: ****:*:*****:** * : :*::*::*** * :** . : * ** * * **:. . :. ** **:*:* : :: *. .: ::. : : :. : . : . . . . ...::.. : .*: :*: . : ** ::: : . . :.. : .:. : .. .. . ... :.:. : :: :. *.: *: :: . * *::*:* . * . ***.: . . : * :***** *** ****** :** : **. :*.:. .... :. .:*: .* . * *.*..: . . . . : . .:: .: : .: .. :.. ...* . . .* :: . ... :. . :* : . . * : . : . * : . :. :: : . : . . . : :: : . * . : * *: :::: * . . . . . : . .* . . : :: . :: * : : *: .....* ... . ... * . * . . : : * ..* *.* : .:..:*. . :: .: : ::. . * . .: . *. .: . : : . ::. * . :.. : :. : * . :... * : :*.: ::. . . * * . .*.* :* *. . : :* .* : : :: :. :.*:::: . : . :*: .**:. *. : . ", "identical_positions": 229, "similar_positions": 401, "identity": "9.13%" }, { "cls_id": "homologset.agr.MGI:2444356", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BXX9-1", "uniprot_id": "CC169_MOUSE", "id": "Q8BXX9-1", "name": "Coiled-coil domain-containing protein 169", "aln": "MGEGHGDTFEGVSTDRLKLELLEEIHMKDVVQLSTLEIRHKIAELEANLN-GDLAGSEWKTRYETQLELNDQLEKQIVSLKEKMEKMRGNPSDRLSSIRVYEKMPVESLNVLLKQLEKEKRSLESQVKEYAFRLEQESKAYHRTNNERRSYIAEMTQVSGSNQVSKRQQMDPLPRMKESPVKTGRHNSMNQKTTNAKKGPVKKVPRSNHLPKLNP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABE7-1", "uniprot_id": "D4ABE7_RAT", "id": "D4ABE7-1", "name": "", "aln": "MGEGHGDTFEGVSTDRLKLELLEEIHMKDVVQLSTLEIRHKIAELEANLN-TDLAGSEWKTRYETQLELNDQLEKQIVSLKEKMEKVRGNPSDRLSSIRVYEKMPVESLNLLLKQLEKEKRSLENQVKDYALKLEQESKVFHRTNSERRSYISEMSQVSGLTQVSKRQQMDPLPRMKESPVKTGRHSSVNQKTTNAKKGPVKKVSRSNHLPKLNP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NNP5-1", "uniprot_id": "CC169_HUMAN", "id": "A6NNP5-1", "name": "Coiled-coil domain-containing protein 169", "aln": "MKEERNYNFDGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLN-TDNEGSEWKTRYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QJK3-1", "uniprot_id": "E9QJK3_DANRE", "id": "E9QJK3-1", "name": "", "aln": "MGESDLGNYE---SSRLHAEVEHEREVKEMLQDSVSDLRNTLADLERRLHSVEEEENEWRTRYETQLELNEQLEKQISVVRERLQTLRSDPSDRLASIRSYEEMSEDALRQRLKLLSSEKSGLQAQLMDFRMRIVQEGKAYQKVYEERRAYLAEIAKLSSTLNLSRKQQMAEARRTAAAPDKTAG-KSTKQHSGAAKKGSVNNTPARSRLPRLKH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .:: :.**: :: .* . *: :* * ::*:.:::** .*: : .**:**********::***** ::*:::.::.:.****:*** **.*. ::*. ** *..** *: *: : ::: **.*.::: .***:*::*::: *. ::*::**: * **. .. :*:: **:*.*:: . .:**.*: ", "identical_positions": 71, "similar_positions": 84, "identity": "33.02%" }, { "cls_id": "homologset.agr.MGI:2444363", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C9H6-1", "uniprot_id": "STRP2_MOUSE", "id": "Q8C9H6-1", "name": "Striatin-interacting proteins 2", "aln": "------------------MDDPAAPGPAGSPANDNGNGNGNGNGNGNGGKGKPAVPK-----------GRETFRNQRRESEGS-------------------------VDCPTLEFEYGDSDGHAAELSELYSYTE-NLEFTTNRKCFEEDFRTQVQDTKEWLE-------LEEDAQKTYVMGLLDRLEVVSREKRLKVARAVLYLAQG----------------TFGECDSEVDVLHWSRYNCFLLYQMGTFSAFLELLHMEIDNSQ-ASSSALRKPAVSIADSTELRVLLSVMYLMVENIRLEREIDPCGWRTARETFRTELSFSTHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKIQKRAELGLPPLAEDSIQVVKS-----MRAASPPSYTLDLGESQLAPPPSKLRGR----------------RG----SRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESAADGERTLDGELDLLEQDPLVPPPPSQTPLS--TDRVAFPKGLPWAPKVRQ-------------KDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADIQIKNEEELEKCPLSLGEEVVPETPSEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPVTVLQSMKLGIDVN---------------RHKEIIVKSISALLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAG---DNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDKP-----------QDSEFSPVDNCLQS----------------------------------VLG-----------------------QRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G7M4-1", "uniprot_id": "A0A8I6G7M4_RAT", "id": "A0A8I6G7M4-1", "name": "", "aln": "------------------MDDPAAPGPSGSPANDNGNGNGNGNGNGNGGKGKPAVPK-----------GREAFRNQRRESEGS-------------------------VDCPTLEFEYGDADGHAAELSELYSYTE-SLEFTTNRKCFEEDFKTQVQDTKEWLE-------LEEDAQKTYVMGLLDRLEVVSREQRLKVARAVLYLAQG----------------TFGECDSEVDVLHWSRYNCFLLYRMGTFSAFLELLHMEIDNSQ-ASSSALRKPAVSIADSTELRVLLSVMYLMVENIRLEREIDPCGWRTARETFRTELSFSTHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKIQKRAELGLPPLAEDSIQVVKS-----MRAASPPSYTLDLGESQLAPPPSKLRGR----------------RG----SRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESASDGERTLDGELDLLEQDPLVPPPPSQTPLS--ADRVSFPKGLPWAPKVRQ-------------KDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADVQIKNEEELEKCPMSLGEEVIPETPSEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPATVLQSMKLGIDVN---------------RHKEIIVKSISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAG---DNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDKP-----------QDSEFSPVDNCLQS----------------------------------VLG-----------------------QRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULQ0-1", "uniprot_id": "STRP2_HUMAN", "id": "Q9ULQ0-1", "name": "Striatin-interacting protein 2", "aln": "------------------MEDPAAPGTGGPPANGNGNG---------GGKGKQAAPK-----------GREAFRSQRRESEGS-------------------------VDCPTLEFEYGDADGHAAELSELYSYTE-NLEFTNNRRCFEEDFKTQVQG-KEWLE-------LEEDAQKAYIMGLLDRLEVVSRERRLKVARAVLYLAQG----------------TFGECDSEVDVLHWSRYNCFLLYQMGTFSTFLELLHMEIDNSQ-ACSSALRKPAVSIADSTELRVLLSVMYLMVENIRLERETDPCGWRTARETFRTELSFSMHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQTLKVQKRAELGLPPLAEDSIQVVKS-----MRAASPPSYTLDLGESQLAPPPSKLRGR----------------RG----SRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESAGDGERTLDGELDLLEQDPLVPPPPSQAPLS--AERVAFPKGLPWAPKVRQ-------------KDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADVQIKNEEELEKCPMSLGEEVVPETPCEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVN---------------RHKEIIVKSISTLLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAG---DNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKLQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDRP-----------QDSEFSPVDNCLQS----------------------------------VLG-----------------------QRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PI62-1", "uniprot_id": "A0A8M9PI62_DANRE", "id": "A0A8M9PI62-1", "name": "", "aln": "---------------------MQQTDDMEVPLIHDSNS-----------NTHTCLPQ-----------ERDGFHQQK-DSEGS-------------------------MESPNLEFEYGDTDSFTAELSELYSYTE-EPEFSLNRDYFEEDFKNHVKG-RRWME-------LSVEEQRAYVMRLLDALEVTDRDKRLKVARAILYLAQG----------------VFDECDTETDVLYWSRHNVFLLYDMGIFTALLELLSMEIDNNQ-ACSSAVRKPAISLADSTELRVLLSIMYLMVETIRVEMESDSPERKAAREAFKMELGSPLYNGEPFALLLFTMVTKFCSMNAPHFPMKKVLLLLWKTILFTLGGFEELQEMKVRMRDHLNLPPLPEDSIKVVRN-----MRAASPPASAMELIEQQQQQKRGRRSRRSAFVDSL---------EGDSPYAKKQPLVKQDSLDTYNERDPFKNDD--ARDEEDDPEDVDSGIEGEVDPLDRDVIIQPPPPPPPLRPPTERMSFPKGLPWAPKVRE-------------KDIEHFLETSRNKFIGFTLGNDIDTLVGLPRPIHESVKTLKLHKYVSIAEVQIKREDELQQCPMTMGEEEVEETPTEILYLGMLPSLSQYVIALLKLLLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVN---------------RHKEIIVKAISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNIMSYISAKNSICALDFPHCAVHEMPELTAESLEAG---DSNQFCWRNLFSCINLLRILNKITKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDIDARPWDFQAEECALRESIEKFNTRRYDKN-----------QNSEFAPVDNCLQS----------------------------------VLG-----------------------QRVDLPEDFHYSYEMWLEREVFSQPIQWEGLLQAQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRD5-1", "uniprot_id": "Q8IRD5_DROME", "id": "Q8IRD5-1", "name": "", "aln": "---------MAWKQKNKLLFDTCKNQLSCGAVNARSSMMQSIQSRINVLNTIAASSKRI---------ERASVDTDTHDADAN-------------------------CDGPDLDFVYADVDGYQNEIAELYSYTE-FSEFQMNVKAFEDQMELYDLP-PNWQK-------QDSASQRGIVMKLVDQLEVSDRSFRMQAARCILYLAQG----------------CWAEVQSDEEQHQITRDNVLVLYQLGVFASFIDLLNMEIESACSPDIVAVKITNVTLVDSTDIRVILSVLYIITETIRDEKEKGSEDYRELADSFVQEINSPLPDGELLAVKLLGMITRFCSGAAPQFPMKKVVLLLWKVSLLGLGGMDVLKNLKNEYRLKVGLEPITEDTLEVTKC-----MRASSPPATATDILENQYPKRNFKRSLMK---------------QRFLDEPEQIDMEMGGNEGQNNANNGSGNGGNGEEELSQYYRPYDDPSSSASTTSTANPNNQPSLTQPPAA--VPPVQITARLPWTPKVRQ-------------KDIDQFLDISRNKFIGYSLIGDHESLAGLPQPIHEGFKTLQRHMYMSLADVQIKKEEDIARNPISTHEDEIKLTPAEVLYQAILPNLPQYMIALLKVLLAASPTSKSKTESINIMADVLPRKMPLTATQSTKLTVDIG---------------RHKEIIVKAVSAIILLYLKHFKINHVYQFEFMSQHLVFANCIPLVLKFFNQTITEYVNTKNSIPLLDFPSCVIGEQPDLSGDSFVYGGEMSDKSYSWRNVFSCINLLRILNKLIKWKHSRVMMLVVFKSAPILKKTLKVRHAMMQLYVLKLLKMQTKYLGRQWRKSNMKTMSAIYAKVRHRLNDDWAFGNDLESRPWDFQAEECTLRACVDRFNLRRYPEATQKCGNNGTAAQNAENAQQSNMMAGNNGCGNNGDANGYGNNGGGGNGGHNQQQQLNDYGVEGGFPSDEILTHSDFAFFGHSGWWDRKVELTDYFKANYAVWLEEEVYNSQTDWDAL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53917-1", "uniprot_id": "FAR11_YEAST", "id": "P53917-1", "name": "Factor arrest protein 11", "aln": "MNASGRSHSKGPIIRSVSLEDLKRNSSFKGNLKYKDEVTSHKEPQVGTLSNEELLKDLDNMLRGKLNMGRNSFHADKRNKSDGNISALTFKARSGLEGDIRTIDIQQDSSDENDNFKFSDDGVNKDRNNEKDNNTDNAVEFQDDAEEAEEENEDESFANVDELDGFDLNKVSDGKHVPINEKGEVDYNMPVDKEFQKSLDQCAASLEERSSAPYALQRAVDWELKMFYSLEDELSEWFCSSDYMHFGQTQTLFKQKITQPQLFFDDENYAASVVECLIEDIPNSLASNLLALSYISMGCFAFTNSKSEHTKIIRRNNLMLVPHIQEIVHAFKKIAISCRDDNRNLKKQTILLFHSSTILYFICSICIEGRGENPEAVNVVIDAFEKTDLLEFLTKYIENWRWNSRLAMRIRNMISLLFKLIVLQFGDSSVYKQTKSSIYNLHGLTYPSKHPEKLSISPLHYQAFREDITSRFPDYNMPSSGLPKDVDKSESLSQFLEIPRPKSKNPLNMALIVPEKHIATPAPSPPSSPQLMHLGEGPRPRKSFQTNMAYPCLYPSDNEGSEDDTLEDRIDLNIERKPDNDIVIPFSTEEAARILSESLEIKLSTKQLWYERDLFMITERGWKQQLENEPYDYAALNHDANSSKEEKSAICIMQRIDKYYKSCLSSFNSLVFVLLQTMESSLTNNFHRKSEVSDKNLLNMLTPQLEIVRAKELSLKSAAGILHALLKWFKLSHILKFEHLAVVIHDSRYINTCASILSK--YSEVYPERVFNKYVQTPNSFWKECSLSNESYRESYSVDDSGEVDTEIMPSFAYLLRILRKVTGNKTQRLKELPLSIGILFKRYYRLFNLDMYHPILKITRELTPFKNKRWKSEHMELISGVYLYEKLELTDNWVTGKDISGELSDACGQEIALRALLQFYNFQHYEIS------------------------------------------------------------------------------------------MEDLGYGHRNSSSQDLLNKESEYLNI----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . * . : : . . . :* :.* . . * . *: ** : *:: . . . :* .:. : . :. * : : . : : . : . * : : ::. . . . :. : ** : : : . . . : : .: : :*: .: . * ..:: :: . : * : . .* : . :: : ** . : .: * . . : . . : . : .: * .. * *: *: .* : : : :. *. .: . :. :* . .*. : *. :.:: *: * :: . :: : * : . .: : : :: *: .*:* :. ** . * : :. : ::. * **: :*: : :: ** **:.*: :**.:: : :. * .::.: . : .:. : . . . .*: :* . ... :::..: * : : . :::: : : :. . ::*: :: : : :**: : * : .::*:..:*: :*.:* : .:.*:*. *:*:... * .:* :** :: :* ::* : : .: ..:: .. : : ", "identical_positions": 71, "similar_positions": 258, "identity": "6.77%" }, { "cls_id": "homologset.agr.MGI:2444364", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F5L4-1", "uniprot_id": "F7F5L4_RAT", "id": "F7F5L4-1", "name": "", "aln": "MRRSPCQLPSMALQCLMLLTGLVVGGMSKSTES------------------------------------KAQQPECCMDVVDVNATCLGTGLCGPGCYRHWNADGSASCVRCWNGTLPTYNGSECRILTGRGMQFPMNRSTGTPGQPHFGGPHVAASLFLGTLFISTGLILSVAGFFYLKRSSKLPEVFYRRDRAPVLQPGETAAMVPLPQSS--------------------------------------------------------------------------------------------------------------------------------------------------VRKPRYIRREQHPEKNRD--PSAFSTVEAHISNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ASP7-1", "uniprot_id": "A2ASP7_MOUSE", "id": "A2ASP7-1", "name": "", "aln": "----------MALQCLLLLTGLLTGGVCKSTES------------------------------------QAQQPECCMDVVDFNATCLGTGLCGPGCYRHWNADGSASCVRCWNGTLPTYNGSECRILTGRGVQLPMNRSTGTPGQPHFGGPHVAASLFLGTLFISTGLILSVAGFFYLKRSSKLPEVFYRRDRAPVLQPGETAAMVPLPQSS--------------------------------------------------------------------------------------------------------------------------------------------------VRKPRYIRREQHPDKNRD--PSAFSTVEAHISNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96HA4-1", "uniprot_id": "CA159_HUMAN", "id": "Q96HA4-1", "name": "Uncharacterized protein C1orf159", "aln": "----------MALRHLALLAGLLVGVASKSMENTVTRNSTAVINTQAEGTLSPPGLSSLPVVREWALTHTAQLPECCVDVVGVNASCPGASLCGPGCYRRWNADGSASCVRCGNGTLPAYNGSECRSFAGPGAPFPMNRSSGTPGRPHPGAPRVAASLFLGTFFISSGLILSVAGFFYLKRSSKLPRACYRRNKAPALQPGEAAAMIPPPQSSGNSSCRIPLWGFPSLGQSQGALWVCPQTGLPGSGSRPPLPGSPGDPPTRQGQGRIWLVPPALDLSWIWPAPPARPPLIPVTSMLFPVPETWGLQERRTHHDRADPQYLLLLEVQLHPRTDAAGLRQALLSSHRFSGAGSGGPKSQPVRKPRYVRRERPLDRATD--PAAFP-GEARISNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8K8-1", "uniprot_id": "A0A8M1P8K8_DANRE", "id": "A0A8M1P8K8-1", "name": "", "aln": "----------MSRAYYIISAVLYVLKIPETKAL------------------------------------LDNSNDCCETIKRMNESCANVSLCEPGP-RHVQENGTTFCVPCAS----ADQGNSTSLNSTRTNQIPVSLIT------VIGGPGVAASVLLGTLLISLGLILSVASFFYLKRSNRLPGVFYRRNKAFIFQPSETAVMIPEASSS--------------------------------------------------------------------------------------------------------------------------------------------------VRKPRYVRRERPSATSTSNSATVATGAVTKVYNV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : : * . :: : :** : .* :* ...** ** *: : :*:: ** * . : :*.. : :*:. : *.* ****::***::** *******.*******.:** . ***::* :**.*:*.*:* ..** ******:***: . .:. . ::: **", "identical_positions": 67, "similar_positions": 57, "identity": "17.05%" }, { "cls_id": "homologset.agr.MGI:2444365", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92565-1", "uniprot_id": "RPGF5_HUMAN", "id": "Q92565-1", "name": "Rap guanine nucleotide exchange factor 5", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSSRLRVFDPHLERKDS------------------------AAALSDRELPLPTFDVP---------------------------------------------------YFKYIDEE----------------DEDDEWSS--------------------RSQSSTED--DSVDSLLS-----------------------------------------------------------------------------------------------------------------------------------------DRYVVVSGTPEKILEHLLNDLHLEEVQDKETETLLDD-----FLLTYTVFMT-----TDDLCQALLRHYSAKKYQGKEENSD---VPRRKRKVLHLVSQWIALYKDWLPE----DEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQKKNKALFHQFSLKENWLQHRGTVTETEEIFCHVYITEHSYVSVKAKVSSIAQEILKVVAEKIQY--AEEDLALVAITFSGEKHELQPNDLVISKSLEASGRIYVYRKDLADTLNPFAENEESQQ-RSMRILGMNTWDLALELMNFDWSLFNSIHEQELIYFTFSRQGSGEHTANLSLLLQRCNEVQLWVATEILLCSQLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHKAYRDAFKKMKP---PKIPFMPLLLKDVTFIHEGNKTFLDN--LVNFEKLHMIADTVRTLRHCRTNQFG--DLSPKEHQELKSYVNHLYVIDS--QQALFELSHRIEPRV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83900-1", "uniprot_id": "RPGF5_RAT", "id": "P83900-1", "name": "Rap guanine nucleotide exchange factor 5", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSSRLRVFDPPLERKD-------------------------SAALSERQLPLPTFDVP---------------------------------------------------YFKYIDEE----------------DEDDEWGS--------------------RSQSSTED--DSVDSLLS-----------------------------------------------------------------------------------------------------------------------------------------DRYVVVSGTPEKILEHLLNDLHLAEVQHKETETLLDD-----FLLTYTVFMT-----TDDLCQALLRHYSAKKYQGEEENSD---VPCRKRKVLHLVSQWISLYKDWLHE----DEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQKKNKALFHQFSLKENWLQHRGTVAETEEIFCHVYVTEHSYISVKAKVSSTAQEILKVVAEKLQR--AEEDLALVAIMFSGEKHEFQPNDLAISKSLEASGRIYVYRKDLADTLNPFAENEESQQ-RSMRILGMNTWDLALELMSFDWSLFNSIHEQELIYFTFSRQGSGEHTVNLSLLLQRCNEVQLWVATEILLCSQLGKRVQLVKKFIKIAAHCKAQQNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHKAYRDAFKKMKP---PKIPFMPLLLKDVTFIHEGNKTFLDN--LVNFEKLHMIADTVRTLRHCRTNQFGS-DMSPKEQQELKSYVNHLYVIDS--QQALFELSHRLEPRA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0Q9-1", "uniprot_id": "RPGF5_MOUSE", "id": "Q8C0Q9-1", "name": "Rap guanine nucleotide exchange factor 5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTGDCQTLSRRISNPYLEHSPSQIYGENSSCA---GRALRNIIILQAADLVKDRVNLKGFYRRSCVGSELVDWLLEHCPFVQCRSMAIGVWQLLLDMGIMSSVDQHLYFQDNYVFYQFSSDECSYLYCE--------FEREEEWQKGVKLLLELVHLIPARAGICDLSHQKTEDSEESSDEILARLTSAVQRELAAVIALKARKSAIEQDDENADKHVTVTEANNGPDPQAGVMCKLQERDDIGRIELVHKLARENCQFLQTEKKESEKLEQQDDEVTMVQVKEQGQSVLVLKK-----------VASCGPAPTSGSAENDARYVVVSGTPEKILEHLLNDLHLAEVQHKETETLLDD-----FLLTYTVFMT-----TDDLCQALLRHYSAKKYQGEEENSD---VPCRKRKVLHLVSQWISLYKDWLHE----DEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGVYRRHTVDEYSPQKKNKALFHQFSLKENWLQHRGTVAETEEIFCHVYITEHSYISVKAKVSSTAQEILKVVAEKLQR--AEEDLALVAITFSGEKHEFQPNDLAISKSLEASGRIYVYRKDLADTLNPLAENEESQQ-RSMRILGMNTWDLALELMSFDWSLFNSIHEQELIYFTFSRQGNGENTVNLSLLLQRCNEVQLWVATEILLCSQLGKRVQLVKKFIKIAAHCKAQQNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHKAYRDAFKKMKP---PKIPFMPLLLKDVTFIHEGNKTFLDN--LVNFEKLHMIADTVRTLRHCRTNQFGS-DVSPKEQQELKSYVNHLYVIDS--QQALFELSHRLEPRA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1Z6P8-1", "uniprot_id": "A1Z6P8_DROME", "id": "A1Z6P8-1", "name": "", "aln": "MAMEWITAMDKRPCDRNLRDVELISCRLRRVEPLCRLPGSALQQLAMCGFYEDLEKGVTLFRAGEQGRFWYAVLGGSLEVRYHAHADADGKSAVTLCNLGVGATFGESVLHDLPRDSTVVTKTTCELLRVEQQDFRLIWEKNKELMNDIFTNCKLKNGFGPSVQATAAATSPTKRPLSPDHPNPALPITETPSPAMNRMGWALRTLLVADNSSCLKDRKVSGKLIRKCAPGTELVDWLVNLSPIVHTRAQAAGMWQALLEEGVLAHVNKEQPFKDKCFLYRFRIDEEGGTAAAGVPQAEDLGAANEHIREALSALFQRGPDATLRMILRKPSHERTSEELELVFEELVHIAALSHLSTSIKRELSSIFVFEAHAQAGTILFNQGDEGRSWYILLKGSVDVVIHGKGTVATLKTGDDFGKLALINDAPRAATIVLKENNCHLLRVDKEHFNRILRDVEANTLRLQEHGKDVLVLERVAKQRGQHSAFKYTVMSGTPAKMLEHLLETRLGQSVGG--MDPFLDD-----FLLTHIVFMP-----VVQLVDELANYFHCDAHEDAQTPEDREYIINFKKRVIQFMQKWVMAVRHAAFE----EPSVCDFIEDLAAEVEADPDLNEETSIVHNVLTQMARYQEDRNQNAGQKWKLPPNGQPICLFSGNATPSKTVIRPDDDIIFRVYCADHTYCTLRFPMHTTAELIKACAADKLQLNRGPEDLVLVEVKSNGERSVFKDNDVSIPTGLSLNGRLFVSVKDHLDALTQLQEQECPTEGVDIDLEILSTKELAYHITLFEWDLFWAVHEYELLYHTFGRHHFGKITANLDVFLRRFNEVQYWIVTELVSTPSLSKRVGLVRKFIKLAAYCKEYQNLNAFFAVVMGLSNMAVSRLQQTWEKIPSKFRKIFQEFEALIDPSRNHRAYRVFVGKLQP---PLIPFMPLLLKDMTFAHEGNKTSLDG--LVNFEKMHMMAQTMRTIRFCRSRSLGLEPPSPKSEGEVRSYISSFRVIDN--QRVLTAMSQKVEPTRKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25300-1", "uniprot_id": "BUD5_YEAST", "id": "P25300-1", "name": "Bud site selection protein 5", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------MSPKNKYVYICVEYIYIYFAKIHKQSTLSSDTTKMFVLIDNVLAYLLEQDD--------------LFVTARFAIQGQIVSRRVNKIHISN------------------------------------------ITDVLLQQFISHT---------------LPYNDNIVP------------KKILDSMRTAVRQLLEATACVSR-------------------------------------------------------------------------------------------------------------------------------------------ECPLVKRSQDIKRARKRLLSDWYRLGADANMDAVLLVVNSAWRFLAVWRPFVNSIQHATQELYQNIAHYLLHGNVNIQRVTALIQLVMGQDDLLFSMDDVLQEVFRIQLYLNKMLPHNSHKWQKPSPFDSANLLLNFRDWTTDNALLQELLLSYPTINKNKHKNHSVPR--LIQIWVESYWQDSETTLKDILNFWYSHLAEYYEYQELFADIVQLFINKKRTRQLKIHY----IGLTDKEIEENKPPLDYENLFLQYEIDKTNANDELCGATDLSDLLFQWKQGE--LLEVEAFALNVSPWSLAKTLTLLESSLYLDIETIEFT------RHFKHNDTTIDSVFTLSNQLSSYVLETTLQQTHT------ISYWLQVALSCLYLRNLNSLASIITSLQNHSIERLSLPIDVKS---DHLFQRLKVVVHPNNNYNVYRRTIKHIFHSQLPCVPFTSLLIRDITFIRDGNDTFTKDGNNVNMQKFNQITKIVAFAQYLQQKQYEDIHCSNTTARSLLGAMIKVHTLYNDNKDRAYQVSIAKVPRLT-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . :: . ::. : : . * : ::**. . :* ** . *: . :* : : .: : . : . :: : . : : : : : :: . : . . .. . .: :: : * : : *:: .*. : . : : . . .* * * : * . :.. .** : :: .*: :. *: : . ..:. .: *::. :: : . : ::::* * :***:: ::: .*.. ::.**. . : . ::*..:: : .*. *:..** . :: * :** .**::*:** ::**.* .. **::*:: ::. : :. : .. * . .: . : . .: . : :* * ", "identical_positions": 50, "similar_positions": 167, "identity": "4.86%" }, { "cls_id": "homologset.agr.MGI:2444386", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CBX0-1", "uniprot_id": "TM63C_MOUSE", "id": "Q8CBX0-1", "name": "Osmosensitive cation channel TMEM63C", "aln": "--MSAFPD-------SMDQK----FHNMTVNECFQ--SRSTVLQGQPFGGIPTVLVLNIILWVFVVLLYSFLRKAAWDYGRLALLIHNDS---LTSLIYG------------------EQSEK-SSPSEVS-LEAERRDRGFSSWFFNSLTMRDRDLINKCGDDARIYITFQYHLIIFVLILCIPSLGIILPVNYIGTVL---DWNSHFGRTTIVNVST-----------------ESKFLWLHSLFAFLYFLINLAFMGHHC-------LGFVPKKSLHFTRTLMITYVPTEIQDPEIISKHFHEAYPGCVVTRVHFCYDVRNLIDLDDQRRHAMR----------GRLYYTAKAKKTGKVMIKTHPCSRLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELN-------------RVQLKRLDLIFVTFQDARTVRRIYDDYKYIHCGRHPKQSSVTTIVKNYHWRVAHAPH---PKDIIWKHLSIRRFSWWTRFIAINTFLFFLFFFLTTPAIIINTID----------IYNVTRPIEKLQSPIVTQFFPSVLLWAFTVTMPLLVYLSAFLEAHWTRSSQNLIIVHKCYIFLVFMVVILPSMGLTSLHVFLRWLFDIYYLEHATIRFQCVFLPDNGAFFINYVITAALLGTGMELMRLGSLCTYCTRLFLSKSEPERVHIRKNQATDFQFGREYAWMLNVFSVVMAYSITCPIIVPFGLLYLCMKHITDRYNMYYSYAPTKLN----AQIHMAAVYQAIFAPLLGLFWML-FFSILRVGS-----LHSITLFSMSSLIISVVIAFSGVFLGKLR------------------IAQRYEQPEEETETVF-DVEPSSTTSTPTSLLYVATVLQEPELNLTPASSPARHTYGTIN-SQPEEGEEESGLRGFARELDSAQFQEGLEMEGQSH------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZNF5-1", "uniprot_id": "TM63C_RAT", "id": "D3ZNF5-1", "name": "Osmosensitive cation channel TMEM63C", "aln": "--MTASPE-------SMGQK----FRNMTANECFQ--SRSTVLQGQPFGGIPTVLLLNIILWVCVVLVYSFLRKAAWDYGRLALLIHNDS---LTSLIYG------------------EQSEK-SSPSEVY-LEAERRDKGFSTWFFNSLTMRDRDLINKCGEDARIYIMFQYHLIIFVLILCIPSLGIILPVNYIGSAL---DWSSHFGRTTIVNVST-----------------ESQFLWLHSIFAFMYFLTNFAFMGHHC-------LGFVPKKNLHFTRTLMITYVPTEIQDPETISKHFHEAYPGCVVTRVHFCYDVRNLIDLDDQRRHAMR----------GRLYYTAKAKKTGKVMIKVHPCSHLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELN-------------RVQLKRLDLIFVTFQDARTVKRIHNDYKYINCGRHPMQSSVTTIVKNNHWRVARAPH---PKDIIWKHLSIRRFSWWARFIAINTSLFFLFFFLTTPAIIINTID----------MYNVTRPIEKLQSPVVTQFFPSVLLWAFTVIMPLLVYFSAFLEAHWTRSNQNLIIMYKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEHATIRFQCVFLPDNGAFFINYVITSALFGTGMELMRLGSLCTYCTRLFLSRSEPERVHIRKNLAMDFQFGREYAWMLNVFSVVMAYSITCPIIVPFGLLYLCMKHITDRYNMYYSYAPTKLN----AQIHMAAVYQAIFAPLLGLFWML-FFSILRVGS-----LHSITLFSLSSIIISVIIAFSGVFLGKFR------------------IAQQYEQPEEETETVF-DVEPSSTTSTPTSLLYVATVLQEPELNLTPASSPARHTYGTMN-SQPEEGEEESGLRGFARELDPAQFQEGLELEGQSH------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P1W3-1", "uniprot_id": "TM63C_HUMAN", "id": "Q9P1W3-1", "name": "Osmosensitive cation channel TMEM63C", "aln": "--MSASPDD-----LSTGGR----LQNMTVDECFQ--SRNTVLQGQPFGGVPTVLCLNIALWVLVLVVYSFLRKAAWDYGRLALLIHNDS---LTSLIYG------------------EQSEK-TSPSETS-LEMERRDKGFCSWFFNSITMKDEDLINKCGDDARIYIVFQYHLIIFVLIICIPSLGIILPINYTGSVL---DWSSHFARTTIVNVST-----------------ESKLLWLHSLLSFFYFITNFMFMAHHC-------LGFAPRNSQKVTRTLMITYVPKDIEDPELIIKHFHEAYPGSVVTRVHFCYDVRNLIDLDDQRRHAMR----------GRLFYTAKAKKTGKVMIRIHPCARLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELN-------------RVPLKRLDLIFVTFQDSRMAKRVRKDYKYVQCGVQPQQSSVTTIVKSYYWRVTMAPH---PKDIIWKHLSVRRFFWWARFIAINTFLFFLFFFLTTPAIIMNTID----------MYNVTRPIEKLQNPIVTQFFPSVMLWGFTVILPLIVYFSAFLEAHWTRSSQNLVMVHKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITAALLGTGMELLRLGSLFCYSTRLFFSRSEPERVNIRKNQAIDFQFGREYAWMMNVFSVVMAYSITCPIIVPFGLLYLCMKHLTDRYNMYYSFAPTKLN----EQIHMAAVSQAIFAPLLGLFWML-FFSILRLGS-----LHAITIFSLSTLLIAMVIAFVGIFLGKLR------------------MVADYEPEEEEIQTVF-DMEPSSTSSTPTSLLYVATVLQEPELNLTPASSPARHTYGTMN-NQPEEGEEESGLRGFARELDSAQFQEGLELEGQNQYH----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WEM4-1", "uniprot_id": "TM63C_DANRE", "id": "X1WEM4-1", "name": "Osmosensitive cation channel TMEM63C", "aln": "MAFESWPAGGVRPVEELDVRSFLMEENSTAERCYRSHSRSSVLQGLPFGGVPTVLAINVVLWLILLLIFSCLRKAAWDYGRLALLMKNDS---LTSLFYG------------------EQSEKEKTPSDSSPSDSETKDMGFCSWLTSLYHMKDEEIRSKCGIDAVTYLSFQRHIILLMMVVCLLSLTIILPVNLSGNLLG--DNPENFGRTTVVNVPA-----------------QNIFLWLHSIFALLYFVITVLCMAHHS-------SRLEYREDEKVARTLMITSIPREISDPGLITKHLHEAYPSCTVTDIHFCFNVQKLMKLDSERRKAMK----------GRLYFTTKAQKNGRIMIKTHPCAQIFCCDICG-FEKVDAEQYYSELEEKLTDEFNAEKN-------------WISMKRLGIAFVTFRDERMTAVIVKDYSRARCRHKPQQSSITTVVRSHQWDVSYAPA---PNDIIWENLSVCGPRWWLRCILLNILLFLLLFFLTTPAIIVNTMD----------KFNVTRPVESLRNPVITQFFPTLLLWAFSILLPFIVYYSSFFEYHWTRSGENQVTMHKCFLLLVFMVIILPSLGLSSLNLFFRWLFDVRFLDETDVKFQCVFLPDNGAFFVNYVITSSLIGTAMELLRIPALLVYSLRLCFAKSKAECIHVKISQAYEFQFGLEYAWTMCIFSVSMTYSITCPVIVPFGLLYLVLKHMVDRYNIYYAYTPTKLN----QRIHAAAISQVVVAPILCMFWLL-FFSVLRLGP-----VQPITLFTFITLLCSIAFSCFGFCMKKLRAD----------------RSTSYQMSDQTTEGGFSDAERSTISTTATANLFIASVLLEPELGLTPMPSPAHQSYGTMVNSQSSVRDAEEDEEKDLEETLETELKDDLLMDSPVAFQ----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NP91-1", "uniprot_id": "TM63_DROME", "id": "Q6NP91-1", "name": "Mechanosensitive cation channel Tmem63", "aln": "----------------MVMS-----ENSNISYCQAVANRTSFFT-TAYNGIPETLILNTIFWVLLILLFTVLRHQAGDFGRLALVNSNGSKKRWTEIFYSRAASVVDPQPSTSTQVSPRPSTTSQGVPDSTPLSPIQPEEGLFGWIRVTLKLRKETILLHTGPDAVHYLSFQQHLMAVMALVTIVSLVIILPVNFLNGPKENPYDVNAFGRTTMANLSP-----------------DSPWLWVHTIITILYIPLVVLIMRRAS-------GRNAFKK--AATRTIMISNISSSDRNKTVVRNYMQELFPDVTIENVSIAYNISRLYVRNAEFERVHE----------ARLYCEHHRNRD-TLMVKPEMCS----------CKKENAYEYYQREERKLSGDVARLRA-------------STMNEPLDIAFITVSTVQEAQNIVTHFTPG---------------TYRQWHLVFAPS---PDDLFWENLNVNKSHWYLKFFCVNAVLFLVLFFLSTPAMVVSLLN----------SRPWVKETEGKISPLVADFLPTLMLWTLSALMPVIVAISDKWMRHYTRSKQNYSIMTKCFGYLLMMIMILPSLGLTSAQALLEWGFLN-----QTDRWQCIFLPDRGSFYVNYIITAAFIGTALELLRFPELIVYIWSLLKAKSKAETPYIRKAILIEFPFGTHYAWTTLVFTIAIVYSVACPLIMPFAMIYICLKHFVDRHNLYFAYGPSNMISRKGGKIHSTAVTMTKFSVVILVLVMA-MICFFRGD-------NGMARFLLLIISLAITLTLFTFMSPIKR--------------------------------CAATRRPSIVEIAGPAPIYVPDVLKDNGIRTSSVRPSAAAFGGYGSDSVSEYDSSQYSVNSVEA------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06538-1", "uniprot_id": "CSC1_YEAST", "id": "Q06538-1", "name": "Calcium permeable stress-gated cation channel 1", "aln": "-------------MTSYIER-----LKSAASYLDTVPDEHHDFRKPTAKVVTTQLTIATSLGIFALLSFSILLK---KWPRLYASRRYKD--------------------------------------DGNLRLPSWNQSSLFGWLTVLYKIRDEQILEYAGLDAYVFLSFFKMCIKLLSIFCFFSVCVISPVRYHFTGKIDDGNDDDDSESSLIHLVKRIVEGSGDGDNHSAPERTNVYLWMYVLFTYFFTFIAIKMAVAETKHVVSTRQAYLGKQNTITDRTIRLSGIPIELRDSEALKTRIEQLKIG-TVSSITICREWGPLNKLFHCRKKILKNLELKYSECPRELRTRQPYSENYHLLGNEQSGAVTHGENVPSSNNNDEDTILYSQISLGERPKMKIGYRGIFGKEVDAIEYLEQQLKFIDAEIIEARKQHYSATPTAFVTMDSVANAQMAAQAVLDPRVHYFITRLAPA---PHDIKWDHVCLSRKDRLTKVYSTTVFIGLSSLFLVIPVSYLATLLNLKTLSKFWPSVGQLLKDHQWAANIVTGLLPTYLFTLLNFGIPYFYEYLTSYQGLVSYSEEEISLVSKNFFYIFVNLFLVFTLAGTASNYWAYLSDTT-----KIAYQLATSVKEFSLFYVDLIILQGIGMFPFKLLLVGSLIGFPLVKIKAKTPRQRNELYN--PPIFNFGLQLPQPILILIITLIYSVMSTKILTSGLAYFIIGFYVYKYQLIFATDHLPHS---TGKVWPLIFRRIIVGLLLFQLTMTGTLAGFEGGW-----VLSSCLFPLPVVTLCFLYDFEKNYLPLSK-------------------------------------------------YIALSSIREYERDNSTVNSANEEESYAYPYAVSELEGPMLD------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03516-1", "uniprot_id": "RSN1_YEAST", "id": "Q03516-1", "name": "Uncharacterized protein RSN1", "aln": "---------------------------MNSTNSTNSTTTATSTNTSTQQVVTSLVSNGTIFGVFVIAFLILRIKLKRIYEPKSSFNLINE-----------------------------------------EKKPEPLPQGVWQWLKPLLKKSDNFVIQQAGLDGYFFLRYLFIIAIYCAVSMSYIFPILLSINASNGNHESGLNQLAYQNVKHRGRYFAHVFCG----------WIFFWGFLYIIYRELYFYTSMKQAVLAS----------PRYAKKLSSRTVLFQTVPKQYLSEEEFSKLFDG------VKRVWIARGSGSIEAMVKARDNMAIQLEG------AETKYLKAALKKIKKLNKKSPQLSVSDNIAEYVPDKKRPHHKINKVAKFFFGKKVDTIS-----------YIKEELPKLNQKVKALQEDHENSSPFNSVFVEFESQYQAQVAAQITTYHAPLFMTPVYIGIEPSDVVWFNLRMFWWERLGREVSAVSAIVALVILWAFPVAFVGMISNITSLTNEVKWLKFIYKLPKQLLGLLTSLAPTVALAVLMSFLPKFIRGMAITQGAPSKQNVEYFTQQAYFAFQVIQVFLVTTLSSAATSTVTEIVKEP----TKAMDLLASNLPKASNFFMSYVILQGLSISSGALLQIVPLILFYVLGAFLDGTVRKKWNRFCGLSSMQWGTAFPVYTNLAVITFSYSIISPLILLFAAVAFFLLYIAYLYNLTYVYQESPDAR---GIYYPRALFQTIVGIYIGQICLLGLFAVGKGWGPIVLQVIGICVTVLIHLHLSAAFDHLSKVIPVDTMKPLDGVSDTPSFKNIYKGIESTKVKKNTFGANIDMDGIKELPEFPIKKYHKRSESVTEQQVENSIFSENTFEYQFNPANEANADGHAINAENLIEDVPLLADGDTMKIPPAPWWKRFLKPHIYYSYKAVKSRLPEIYGLVDPDERVNDFDISHAYDYPAVSAQCPELWIPRDPFGFSKLLISDVSGVVEMNDENATIDENLKFTLRDVPPPYNDVKDEANGEANGEFDTASKENNPFADPKYKEEESRSAV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : : : : : : . .. *: .. : * *. :: : : . :: .:. . . ::: : :: . **: : :. . . . . :. : : :. : . . . : . .: .. . :. . : . * *: * :: : : : :: *. : : ::: : *: : : :* : : . : : .. :.:: ::. :: . : . . *::. :* .: *: . * : . : :* . : : : **: .. *: . : : . . ::: : . .. : : : :. . : : . .. . .. . ", "identical_positions": 19, "similar_positions": 152, "identity": "1.77%" }, { "cls_id": "homologset.agr.MGI:2444387", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8S9-1", "uniprot_id": "D3Z8S9_RAT", "id": "D3Z8S9-1", "name": "", "aln": "MDLVITQELARARNQQDATALRRAYELIKSANLGKSELDPTESFSPDLFVLCAEQALKMKEPEMSEDCIQMYFKVKAPVTQFLGRAHLCRAQLCAPQSEENVEDFENCVTQYMKAINFAKGEPRYYFLVFNASVLYWRMVRPFLKPGYHHFVIPSLSQIVNVLNQTEEEDKEWRAELMIELLECYLQAGRKEDATRFCMTAAPFVKTQVPHKYRQMFSTMVRHEVMDDEMLREEKKHSVTLSVTYHINSLKAKLDKNDLPENLEQILKKLYKNLSQYHHQQSPHIQEEKILLLFELGRLCLTLKNEKIASDCLIYLKKMENEDPSKLLEIEGLECELDALRLESKLKLYLRGAVEEQLIIIKRLDNILQRAIRLGNPTTIHVLCTAQWNICLPLLQRNLRHHLRKPLTNIAEILEKVDSLMILMRCQVHMEMAYIEQDDDRVEPAIEHMQKAMRLDSLGRYTDKIKITFRRLQLSTLLYQSPDRPEDKATMAIEQAKKATPKDSARKKRAILVNAGLALAPDTFQIVLDSENEAKVSIGKIKGRFTYLYAKARHHTLCVDKAAGHLRRLGFENDKERIVIWAELAKVAWQQDVWDVCRTATRFCLLYDNAKSKKSTKPKRGKKKKGMEGSVTE--GPSEVVLNKQMSPDLLRKIAEVAFISAEATVHFLRLEGIQLNNQAIPPEDLSQHPAGYVPEPPESNSEWITYRTWIESLSQYAMNNWLRAAEVGQELGESWIVQNAVVYVLNHNRHLILAGRQKELVDSLFHLLNIVKVTGYTGDSVMLVMLCNALARGLIISWIPTQTPEKSKRNVRPTLVHGPLDSSALSEIRSAVEVCEFALNLTNGNVPEDIVPTNVRQHLISTWVKAKQLLQQQIGQRLAIDEWQGTNEDINSVTRVLVALEMYSCNGLGLMDFTVPPLGQVVKMASECNWSDHLVELQTLTRLTHFAYMAHDHEVTISCSQNAIQMGLKHLRLFEPINAKLAAEMLCMVSCIKGRSIMENLKGRKQLRLAAAKAFVESARFGGLANSSSLVMMAARHYWNAWLPLLSSRANRKKAKGSLQRIISIINKTEHKKQETEKTLPLHQWPTADFQTGGTGPEVQFLPGAEDDLTLRAALYTLLFNSHADKNDWEMGLKVLDEAVQVLPRTAHRLLIFKHMVIVKAKLGQNFTMEIQKFKDEREDYLAHMWYRLAQNSRNVCGVLTCYQNAIQALQKPENNWQKVDYIVEFSEWMYYKQFPLEDVFDHLEWAIEILLCMKASEDALESDPKKEGQASLAQSPTDNEMPSNLETVLLNHFRSVRQLESLARVHVLRALMASPSTSSHDDDCLVAYGLFKHILQISLTEGTKQVSE-RYLQLATSQLLLTKKEKEKEKEKEKEKEKE-------------------------------------------------------------KEKEKEKEKE-KVKDMKQISTPASNKPPDDIPISIGEWASYSCSEDLLSVFKQDKSDYTINSTSFQKPTHTLYYIDHLAKALQKMYLHELSIPILQLGVLIAEVVVESKSLADLYHLRLFQVCSDLRLHYAATHHEEVVGQAYFGDMEQASCRKEIAFKKEKNKEPIVEDSLPALHEQLAPAQSAEVKPLIWQDTILKINEETGKGLDGTSYPQLWILKGEVLLDLELHQPARLLLSEAQHAFQELGDTCAEAQCLLLLAELANKEKNHGQAMLLIERAQQLGGAEEFWYNLTLTLAESILSSEDEGKEISVCGLFQKLIETFRTLQSERPNRVSILEFFIMELEARCVKLQSRFACNMIGKELKKYPLLLKELEDHLLEVEENFVSGGYHKNYVDLKLEHARIKRLCAQNEKDEEQKTAYYLEMYSLSQKAISEEEE---------------------LFHRVQGMLSLQDLQNINSPLMRRLARLKLSLAETCLELLQIVCKETLELQMEQNSFEKLLADFLQNTSDYSSIGLQWFFLKRTLPHLVLAQLESLHPLCVGCMDIRAQLLILAGKALHVLSVQTDPVYPSFCWEEELLVGAKQNSPKSLEMDTEDKSVETSSRNSMVFKEAPKEQNRKAEGLRKSVMLAQRFLAQTSEVLLQCIQTALSSNLLDIVATASIEMVECIGVLDPITTCHFLTLSQSCSTSEMARKILLTATSNTSSSQLAALLQLHQRLRQQDKMSTSLFASIEQKLATTFRAWQSLCVTDQHFNILNEIPPMFQILFLQHSQDRSYLYGAAFERPRTMPTLKGKTVVVGGHCKVTRVATSPTAISDLLTKVQLFRRHAQVQKF-------------KTMPVQQDLSIQSLSTILEHTEEYLKPITPLFTFPDTRNQMPTAVSDAGKNKGKDKERKAS---LPSGQPD-PEYMILIVDKLLLDLPLEGLSVFNE--VTSLSRDFSLQMLWNRLHKEEKEGIVKKEIKSKEIKKKTPGKKG-KNAMVRIIPPECTLIDSDTIKFVVDPFEEAQGPELLRPVTVTQEILEKYQDLFTARWMGHLGSYQFPSQADWEQVLNSCRGFFFYGMENFLSHLEVERLVAMDLQECQMMVLLDLTRSFKSRKRKIESAENQ------------SASQR---------------SLERPIETAILLSLTGTESIVGNQWPTPLKDNMLRATLLWDNLL---AIGKPLGKTVRLIHRLRNE--PDNQDKDPQVSKDELLPGLQPHHFEPLAT--ALNWVLY-------------------------GLPHQAIV-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q2C0-1", "uniprot_id": "E9Q2C0_MOUSE", "id": "E9Q2C0-1", "name": "", "aln": "MDLIITQELARARNQQDATALRRAYELIKSANLGKSELDPTESFSPDLFVLCAEQALKMKEPEISEDCIQMYFKVKAPITQFLGRAHLCRAQLCAPQSEENVEEFENCVTQYMKAINFAKGEPRYYFLVFNASVLYWNMVRPFLKPGYHHLVIPSLSQIITVLNQTEEEDKEWRAELMLELLECYLQAGRKEDATKFCLTAAPFVRTQVPHKYRQMFSTMVRYEVLDDLMLREDKQQSIILSITYHINSLKAKLDKNNLPENLEQILRKMYRDLSQYHDQHVPTIREEKILLLFELGRLCLTLKNEPIASDCLQYLKKMETEDTGKLLEMEGLECELDALRLGSKLKMYLRGAVEEQLLIIKRMDNILQRAIRLGNPTTIHVLCTAQWNICLPLLQHNLRHHLRKPLTNIAEILEKVDSLMILLRCQVHMEMAYIEQDDDRVEPAIEHMQKAMRLDSLGIYRDKIKITYRRLQLGTMLYQSPDRPEDKATMAIEQAKKATPKDSARKKRAILVNAGLALAPDTFQIVLDSENESKVSIGKIKGRFTYLCAKARHHILSVDKAAGHLRRLGYENDKDRIVIWAELAKVAWQQDVWDVCRTASRFCLLYDNVKAKRSTKLKRGRKKKVIEGSMSDW-APSDMAMHKQMPPDLLRKIAKVLFISAEATVHLLRSEGVQLNNQAIPPEDLSQHPAGYVPEPPESNSEWITYRTWIENLSQYAMNNWMRAAEIGQELGESWIVQNAVVYVLNHNRHLILAGRQKELVESLFHFLSIIKIVGYTEDSVMLVMLCNALARGLIMSWIPTQTPEKSKKNVRPTLVHGPLESSTLSDIRAAVEVCEFALNLTNGNVPEDIVPTNVRQHLIATWVKAKQLLQQQIGQRLGTDE-QSTNEDISSVTRVLVALEMYSCNGLGLMDFTVPPLVQVVKMASECNWSDHLVELQTLTRLTHFAYMAHDHEVTMACSQNATQMGLKHLRSFEPSNAKLAAEMLCMVSCIQGRSIMENLKGRKQLRLAAAKAFVESARFGGLANSNSLVMMAARHYWNTWLPLLSSPANRKKAKASLQRIISIINKTENKKQETDKTLPLHQWPSADFQTGGTGPEIPFLPGAEDDLTLRAALYTLLFNSHADRNDWEMGLKVLDEAVQVLPRTAHRLLIFKHMVIVKAKLGQNFTMEIQKFKDEKESYLASMWYRLAQNSKTVCGELSCYQNAIQALQKPENNWQKVDYIMEFSEWMYYKQFPLDDVFDHLDWAIEILLSMKPNEDALEPEPKKEGQASPAQSLTESTVPSN-QTASLDQFRSVRQLEALARVHILRALMASPSASSYEDDCLMAYSFFKHILQISLTEGVKLIPE-KNLQAVSSQLLLTKKEKEKEKEKEKEREKKEKEKKEKKEKKEEKKEEKKEEKKEEKEEKEEKKEEKKEEKKEKEEEKEKKEKEKKEKEKEKKEKEKEREKE-KVKDTKQISTSASNKPPDEIPTSIGEWASYSCSEDLLHVFKQDKSDCTINSSSFQKPTYSLYYIDHLAKALQKMFLHELSIPILQLGVLIAEAVVESKSLADLYHLRLLQVCSDLRLHYAATHHEEVIGQAYFGDMEQASCRKEIAFKKEKNKEPEMEDYLPTLHEQLTLSDSVEVKALIAQDKILKINGETGKGLEGTSYPQLWLLKGEVLLELELHQPARLLLSEAQWAFQELGDICSEAQSLLLLAELANKEKNHAQAMLMVERAQQLGGAEEFWYKSTLTLAEAILSSEDRRKEISVCSLFQKLIDTFRALQNERPNRVSLLEFLIMELEARCVKLRIQFACNLTDEEFNEHPFLLRELEDHLLEVEQNLIFGGYYKNYVDLKLDHAKIKRLCAQKEKDEEQKTAYYLEMYSLSQKAVSEEEE---------------------VFHRIQALLSLHDLQNINSPVMRRLARLKLSLAETCLDLLQLVCKEALDLQMEQGSFEKLLADFLQNTTDYTSIGLQWFFLKRTLPHLVLTQLESLQPLCVGCTDIRAQLLILAGKALHLLYVQTDPVYPSFCWEEELLVGTKKDSLRSLETDTEDRSVETSS--SAVFKEAPKEQSRKAEGLKKRMVLARGFLAQTSEVLLQCIQTSLSNNLLDIVASASIEMVECIGILDPITTCQFLTLSQSCSTSEMMRKVLLTATKNTGSSQLAALLQLHQRLRQQDKMSTSLFASVEQKLASSFRAWQSLCVTEQHFSILNEIPPVFRILFLQHSQDRSCLYGAAFERPKTMPSPKGKLITVGGYCKVTRVATSPTAISDLLTSIQWFQRQTRVK--------------------EQALCTQSLSSILEHMEDYLKPITPQLTFPESRNQMPTAVGDAGKNKGREKERKIS---LPSGQPD-PEYLILIVDKFLLELPLEGLSMLNE--VTSLSRDFSLQMLWNRLHKEEREGSMKKEVKSKDLKKKTPGKKALKSIMTRIIPPECNLIDSDTIKFVVDPYEEARGTELMRPIEITQEILEKYRDTFTGRWMGHLGNHNFPSQADWEQLLDSCRGFFFYGMETFLSHLEIERLVAMNLQECQMMILLDLTRSSHSQKRTIESSEGQ------------SASQR---------------SLVKPIQTAILLSLVGVESIVDNQWPTLMQDNMLRATILWDNLL---AIGKPLGKTVRLIHKLCNE--PGSQDEKPQVSKNEPLSELQPHHPESLTT--ALNWVLY-------------------------GLPHQAIV-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYW2-1", "uniprot_id": "CFA46_HUMAN", "id": "Q8IYW2-1", "name": "Cilia- and flagella-associated protein 46", "aln": "MDLVITQELARAESQQDAASLKKAYELIKSANLGKSEFDPSESFSPDLFVLCAEQALKMRQPEVSEDCIQMYFKVKAPITQFLGRAHLCRAQMCAPKSAENLEEFENCVTEYMKAINFAKGEPRYYFLVYNASVLYWQMVRPFLKPGYRHHLIPSLSQIINVLSQTEEEDKEWRAELMLELLECYLQAGRKEEAARFCSTAAPFIKSHVPQKYRQIFSVMVRHELMDELQLKEEKKNSISLSVTFYINMLKAKAEQNDLPGDISVILRKAYRHLGHYNHQRFPSISEEKMLLLFELARFSLTLKCMEISSACLSDLKKMESKDPGKLIEMECLECESEALRLESKMKVYNRAAVEAQLDIIQRLDVALQRAVRLGDPRVIHVVCATQWNTCLPLLQHNLRHHLRKPLAGVADVLEKLDSLMTLLRCQVHMEMAQIEEDEDRLEPATEHLRKAARLDSLGLYRDRIQMASTRLRLCTTLYQAPERAEDKAIMAVEQAKKATPKDSVRKKRALLVNAGLALAPDAFQIVLDSENEAKVSTGKNRGRFTYLCAKAWHHTVSVDKAAGHLRRLGNENDKERIQIWAELAKVARKQGVWDVCRTASRFCLLYDNVKVKK-LRLRRGKKKRGRDGSVQDTWSQPEVVLQRQVCPDLLRKFAEVGFIHAEATVHLLRSEGVELNDRAIPPEDLSQHPAGYVPEPPEVNAEWITYRTWIESLSRCAMNNWLRSAEIGQEIQEAWIVQNAVVYVLNHNHHLILAGRQKELVDALYHLLSIVKATGHSGDPVMLVTLCNTLARGLIISWIPVQAAEKSRKFMRPNAFHSPLDAGATSEIKTAVEVCEFALNLTNGSAPEETVPTGTRQQLIATWVKAKQLLQQQIGPRLGTEE-QGTNEDVSSVTRVLVALEMYSCNGLGLMDFTVPSLAQLVKMASECNWSDPLVELQTLTRLTHFAHAARDHETTMACAHRALEMGIKYLKKFGPEESRLVAEMLCTATAIQGRSIMENLKGRKQLRLVAAKAFTESARFGGIAGSSALVMLAARHYWNAWLPLLSSAVYRKKAKGALKRLIGIINKTEARKQEKGKTLLLHQWPTADFQGGGT-TEGYFLPGAEDDLALRAALYGLLFHSHADQDDWEGGLKVLDEAVQVLPRTAHRLLIFKHMVIVKAKLGQNFSMEIQKFKAESEDYLARMWHRLALNSPSVSGELACYNNAIQALQKPEMEWQKVEYLMEFGQWLHHRHFPLEDVVFHLRWAVEILLAMKPPGDVPEPQPTPDGEYVAVEMPPRSPVSEAEEAVSLEQLRSVRQLEALARVHILLALVLSPGAEGYEDCCLAAYAFFRHIWQVSLMTAGKSVLENRPLAATSSHLLLPKKEKENERSKEKEKERSKEKENERS-----------------------------------------------------KEKDKEKGKEEKVKEPKQSQSPAPIKQLEDLPMSIEEWASYSCPEEVLSVLKQDRSDSTVNPSSIQKPTYSLYFLDHLVKALQKMCLHELTVPVLQLGVLISDSVVGSKGLSDLYHLRLAHACSELKLREAAARHEEAVGQVCVSELEQASCRKEIALKKEKNKEPLLEESLPALNEQTLPVQPGEIKPLDAKDKILKMNGETGRDLDGTSFPHLWMLKAEVLLEMNLYQPARLLLSEAYLAFQELDEPCAEAQCLLLLAQLANKEKNYGQAKKMIAQAQHLGGSEEFWYNSTLTLAEALLSMEHSGREATVCHIFQKLINAFKILKKERPNRLPLLEFMITDLEARCLSLRVRVAQHSAVTEPTECSLLLKEMDDGLLEIERKFIDCGCKENCVDVKLERAKIKRLRAQNEKDEEQKTAYYLEAYGLAQGAVAEEEGRLHSIQGLYGLAQGAMAEEEGRLHSVQGLLSLQDLQNVNTPLMRKLARLKLGLVEMALDMLQFIWEEAHGQQSEQGSLEKLLADYLQNTSDYTSVGLQWFTLKRTLAHGALAQLGSLQPLSVGCVEIRARLLGLAGRALHLLAMQADPVHPTCYWEAGPSVGAKLSGLKSLELEVEEEGATKSSRDPPASRAAPEEHCRRGEDLKRRMVLAQQYLAQASEVLLQCLQVALGSGLLDVAAAASLEMVECVGTLDPATTCQFLALSQSCSASETMRDVLLAATANTSSSQLAALLQLQHQLRCQDRTTTSLGARVEQRLAAVSKAWQNLCVTEQHFNLLNEMPPTFWILFLHLSGDRSRLYGAAYEKPKFITAAKGKVQAVGGSCKVMRLAISPTAFSHLLACAQQFRKQTQAQVYSEDMALNIGSEPEGLQVEEKERPVQRLSSVLGPLEELLQPLFPLLSLSKARVQTPAVVADSGKSKGKDKERKTSTGQHSTVQPEVADKIVLVADRHLLELPLEGLSVFDEGTISSVSREFSLQMLWNRLHKEETEGGVKKEGRSRDPKKRSLAKKGRKGSIPRTIPPDCIIVDSDNFKFVVDPYEEAQGPEMLTPVSITQDILERFQDTFTSRWAGHLGSKHFPSQAQWEQALGSCSGFFFYGMESFLSHILVERLVAMNLQECQVAVLLDLARSYQSLKRHMESVEHRRSVGRWEANWRNSASPSEDEWRRGGEPRRGFSDLEGQAAAAPKLRAPSHHAQLGPVWAAAPSHRVVQAWTCLPSAAGAPALASALGSAPLPTHPHLPAPIPSSQLALPFLGLSPALGAASARDPPPATSRKAAAWTSSSACLCAPWGLRRGWSCVSSRGQDKGGLPLAALVLSCLDQKTIQTVSLFLI", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:********..****::*::**************:**:******************::**:**************:*************:***:* **:*:******:******************:*******.**********:* :*******:.**.**************:*************:*::** *****::::**:****:**.***:*::*: *:*:*::*: **:*::** **** ::*:** ::. **:* *:.*.:*:.*: * * ***:******.*:.**** *:* ** *****.:*..**:*:* **** :**** **:*:* *.*** ** **:*:* ****:***:* .***:*::*** ******:**********:.:*::***:**** *:********* **:*:**:*** **::** ****** * *:*::: **:* * ***:*:*.**** **:***********.*****:***********:**********:*** ** :****** *** ** :.************ ****:** ********* :*.********:********.* *: : :**:**: :**: : . .::.:::*: ******:*:* ** ******:** **::**::******************** *:**********.**: *****:*:**:***: *:**************:************::*:*:*.*:* .*:: *.**** ***:******:****.*:.***:: :**. .*.**::.: *:*::**************..**: ***..**:**:************** **. :* *.****:.*************************.* *:*********** **************: *:***.*::*::.* :**:*:*: * * :::*.***** .:.*:****************.*****.*******:*.*.:***:*******:******* . *****.:*:*:*.****** :***. *** *****:**** *** .* *********:****** ***:****::*** ************************************:******* * *.*** **:*** ** .*.* *:**:********** :****:*::**.:*:::::***:**. ** **:****.**. *. *.:*. :*: .: . . :.. ::. *:::*******:*****:* **: **.:..::* ** **.:*:** *:** . * : * : * .:*:***.*****:*:.****:*:. ***:**: ** ***: ** .:.*. * :::* ** *******.*::* *:***:** *:*.:*:****::**::***.****** ****::*:*******:: ** **.*:******* :.**:*:*: **::***.:**. ..::**********:******** :*: **:*:** :. *:*.* :*.***:* ***:.*:***:*:**:**.****:::*:********** *****.: *:***.*****:*******:.** :: :**:***:*****: ******::** *. :* :** :*****::*: *:.*****:.:***:* :*****:.*: :.* : * .: .:**:*::* ***:*.::: * :* **:**::*:**** **:************* *.*:* *::*** :* :*.:***:****:*:*:**:******.*.* .*::**:: :*: * **.*:******:****:**:*:***** *****.* .*:** **:**.*** :***:** ***:***:* :*:***:*: ** **:* .. :*** :.*:... .** . . : **:*: *:.*.*:: ::**: :***:*******:*.:*...***:.*:**:*****:* *** ***:**:******:** *.:**:** **.**********:::** **: :*** * :**:**: :***.****:***.:***:** * ****: * *** *****:*:*: :.: *** .*** *** *:* ****:*.**: * *:::::.: :: * **::* *: *:*: * :::..:* * *:.*.*:**.**::**** * .: **: .: ::*:.*: **:*******:::* ::*:**:************** ** :*** :*:: **:: .**. *. : * ***:* ::***.:******:***:*.*:: *: :**:***:::* **.** ****. :*****:*** *.** ********.****: :******:*****: :****:** :* ** :** * : *** .* :* * . .: :. *.: ...:::* . *:...**.: * *..* * :. . * ..:. . :: * *. *** *:* ", "identical_positions": 1585, "similar_positions": 658, "identity": "57.2%" }, { "cls_id": "homologset.agr.MGI:2444389", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACC3-1", "uniprot_id": "D4ACC3_RAT", "id": "D4ACC3-1", "name": "", "aln": "MAS---AEPLTALSRWYLYAIHGYFCEVMFTAAWEFVVNFNWKFPGVTSVWALFIYGTSILIVERMYLRLRGRCPLLVRCVIYTLWTYLWEFTTGFILRQFNACPWDYSQFDFDFMGLITLEYAVPWFCGALIMEQFIIRNTLRLRFDKDAEPGEPAS-------------------PPALANGHVKTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFQ2-1", "uniprot_id": "T229B_MOUSE", "id": "Q8BFQ2-1", "name": "Transmembrane protein 229B", "aln": "MAS---AEPLTALSRWYLYAIHGYFCEVMFTAAWEFVVNFNWKFPGVTSVWALFIYGTSILIVERMYLRLRGRCPLLVRCVIYTLWTYLWEFTTGFILRQFNACPWDYSQFDFDFMGLITLEYAVPWFCGALIMEQFIIRNTLRLRFDKDAEPGEPAS-------------------PPALANGHVKTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBD8-1", "uniprot_id": "T229B_HUMAN", "id": "Q8NBD8-1", "name": "Transmembrane protein 229B", "aln": "MAS---AEPLTALSRWYLYAIHGYFCEVMFTAAWEFVVNLNWKFPGVTSVWALFIYGTSILIVERMYLRLRGRCPLLLRCLIYTLWTYLWEFTTGFILRQFNACPWDYSQFDFDFMGLITLEYAVPWFCGALIMEQFIIRNTLRLRFDKDAEPGEPSG-------------------ALALANGHVKTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08CG9-1", "uniprot_id": "T229B_DANRE", "id": "Q08CG9-1", "name": "Transmembrane protein 229b", "aln": "MATTVTPEPLTALSRWYLYAIHGYFCEVMFTAAWEFVVNCNWKFPGVTSVWALFIYGTCILIVERMYLCLKDRCNVLLRCIIYTLWTYFWEFGTGFLLRQFNACPWDYSEFKYNFMGLITAEYAVPWFCASFIVERLVIRNTLRLRFDEVAESGQAEERLDRGGGGRGGRRGRGARAGATSANGYVKVD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: .******************************** ******************.********* *:.** :*:**:*******:*** ***:************:*.::****** ********.::*:*:::**********: **.*:. : ***:**.*", "identical_positions": 128, "similar_positions": 28, "identity": "67.72%" }, { "cls_id": "homologset.agr.MGI:2444391", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0U1RRT2-1", "uniprot_id": "A0A0U1RRT2_RAT", "id": "A0A0U1RRT2-1", "name": "Solute carrier family 25 member 44", "aln": "MARGMPEDPELAVQEPDRRSPGNMEGKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFVKILRADGVTGLYRGFLVNTFTLISGQCYVTTYELTRKFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVR---GNLEGQGLIAFGQTKDIIRQILRADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSRLCPQECPHIVFQAISGPLAAATASVLTNPMDVIRTRVQVEGKSSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGF9-1", "uniprot_id": "S2544_MOUSE", "id": "Q8BGF9-1", "name": "Solute carrier family 25 member 44", "aln": "-----------------------MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFVKILRADGVAGLYRGFLVNTFTLISGQCYVTTYELTRKFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVH---GNLEGQGVIAFGQTKDIIRQILRADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSRLCPQECPHIVFQAISGPLAAATASILTNPMDVIRTRVQVEGKSSIVLTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96H78-1", "uniprot_id": "S2544_HUMAN", "id": "Q96H78-1", "name": "Solute carrier family 25 member 44", "aln": "-----------------------MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLISGQCYVTTYELTRKFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVR---GNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N354-1", "uniprot_id": "A0A8M1N354_DANRE", "id": "A0A8M1N354-1", "name": "", "aln": "----------------------MMQQKRNIQIIEWEDLDKRKFYSLGVFMTMTTRAAVYPFTLIRTRLQVQKGKSLYNGTFDAFCKILKVEGARGLYRGFMINTFTLISGQAYITTYELVRKYVSWYSSNNTVKSLVAGGAASLVAQSITVPIDVVSQQLMVQGQGCQLTRFKLKPKMAMATGKHKYTFGQTRDIVVQIFHADGFRGFYRGYVASLLTYIPNSAVWWPFYHFYGEQLSRLAPADCPHLILQAIAGPMAAATASTLTNPMDVVRARVQVEGRSSVIETFKQLMAEEGIWGLTKGLSARIISSTPTSIMIVIGYETLKRLSLRPELVHSRHW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC40-1", "uniprot_id": "Q9VC40_DROME", "id": "Q9VC40-1", "name": "Solute carrier family 25 member 44", "aln": "-MTESSSSTKSRLAVAPTGVGGAAEGATYIRTIEWDMMNKTKFFPLSMLSSFSVRCCLFPLTVIKTQLQVQHKSDVYKGMVDCAMKIYRSEGVPGLYRGFWISSVQIVSGVFYISTYEGVRHVLNDLGAGHRMKALAGGGCASLVGQTIIVPFDVISQHAMVLGMSAHAGSKGDINPLGIKSWPGRSRLHISMDIGREIMRRDGFRGFYRGYTASLMAYVPNSAMWWAFYHLYQDELFRICPVWVSHLFIQCVAGSLGGFTTTILTNPLDIVRARLQVHRLDSMSVAFRELWQEEKLNCFFKGLSARLVQSAAFSFSIILGYETIKRIAVDEQYKHQIRW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: ***: ::* **: :.: :: * .::*:*:*:*:****: ..:*:* .*. ** : :* ****** :.:. ::** *::*** .*: : . .: :*:*..**.****.*:* **:**:**: *: . : . : : ** :*:: **:*******.***::*:****:**.***:* ::* :.* .*:.:*.::*.:.. *:: ****:*::*:*:**. .*: :*::* ** : ******::.::. :: *::***::*:::: : .. :*", "identical_positions": 110, "similar_positions": 117, "identity": "32.35%" }, { "cls_id": "homologset.agr.MGI:2444392", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P6V1-1", "uniprot_id": "GLT11_RAT", "id": "Q6P6V1-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 11", "aln": "---MGSVTIRYFCYGCLFTSATWTVLLFIYFNFS-EVTQPLRNVPIKGSGPHGPFPKKFYPRFTRGPGRVLEPQFKANRMDDLMNNNIEDPDKGLSKSSSELGMIFNERDQELRDLGYQKHAFNMLISNRLGYHRDVPDTRNAECRGK--SYPTDLPTASVVICFYNEAFSALLRTVHSVVDRTPAHLLHEIILVDDSSDFDDLKGELDEYIQRYLP-AKVKVIRNMKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAIILEDPHTVVCPVIDIISADTLAYSSSPVVRGGFNWGLHFKWDLVPVSDLGGADSATAPIRSPTMAGGLFAMNRQYFNDLGQYDSGMDIWGGENLEISFRIWMCGGKLFIIPCSRVGHIFRKRRPYGSPEGQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKTKSFGNISERVELRKKLGCQSFKWYLDNVYPEMQVSGPKARLQQ--PVFINRGPKRPRVLLRGRLYHLQTNKCLVAQGRSSQ----KGGLVLLKACDYGDPTQVWIYNEEHELILNNLLCLDMSETRSSDPPRLMKCHGSGGSQQWTFGK--NNRLYQVSVGQCLRVVDQMDQKGYVGMAICDGSSSQ--QWRLEG---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921L8-1", "uniprot_id": "GLT11_MOUSE", "id": "Q921L8-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 11", "aln": "---MGSITVRYFCYGCLFTSATWTVLLFIYFNFS-EVTQPLRNVPIKGSGPHGPFPKKFYPRFTRGPGRVLDPQFKANRIDRLMNNHIEDPDKGLSKSSSELGMIFNERDQELRDLGYQKHAFNMLISNRLGYHRDVPDTRNAECRRK--SYPTDLPTASIVICFYNEAFSALLRTVHSVVDRTPAHLLHEIILVDDSSDFDDLKGELDEYIQRYLP-AKVKVIRNMKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAIILEDPHTVVCPVIDIISADTLAYSSSPVVRGGFNWGLHFKWDLVPVSELGGPDGATAPIRSPTMAGGLFAMNRQYFNDLGQYDSGMDIWGGENLEISFRIWMCGGKLFILPCSRVGHIFRKRRPYGSPEGQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKNKSFGNISERVELRKKLGCQSFKWYLDNIYPEMQIPGPNAKPQQ--PVLINRGPKRPRVLQRGRLYHLQTNKCLVAQGRSSQ----KGGLVLLKTCDYGDPTQVWIYNEDHELILNNLLCLDMSETRSSDPPRLMKCHGSGGSQQWTFGK--NNRLYQVSVGQCLRVMDLMDQKGYVGMAICDGSSSQ--QWRLEG---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCW6-1", "uniprot_id": "GLT11_HUMAN", "id": "Q8NCW6-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 11", "aln": "---MGSVTVRYFCYGCLFTSATWTVLLFVYFNFS-EVTQPLKNVPVKGSGPHGPSPKKFYPRFTRGPSRVLEPQFKANKIDDVIDSRVEDPEEGHLKFSSELGMIFNERDQELRDLGYQKHAFNMLISDRLGYHRDVPDTRNAACKEK--FYPPDLPAASVVICFYNEAFSALLRTVHSVIDRTPAHLLHEIILVDDDSDFDDLKGELDEYVQKYLP-GKIKVIRNTKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAAIREDRHTVVCPVIDIISADTLAYSSSPVVRGGFNWGLHFKWDLVPLSELGRAEGATAPIKSPTMAGGLFAMNRQYFHELGQYDSGMDIWGGENLEISFRIWMCGGKLFIIPCSRVGHIFRKRRPYGSPEGQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKTKSYGNISERVELRKKLGCKSFKWYLDNVYPEMQISGSHAKPQQ--PIFVNRGPKRPKVLQRGRLYHLQTNKCLVAQGRPSQ----KGGLVVLKACDYSDPNQIWIYNEEHELVLNSLLCLDMSETRSSDPPRLMKCHGSGGSQQWTFGK--NNRLYQVSVGQCLRAVDPLGQKGSVAMAICDGSSSQ--QWHLEG---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R7M5-1", "uniprot_id": "F1R7M5_DANRE", "id": "F1R7M5-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "---MGSVTLRYFCYGCLFTSVTWSILLFLYFNLSQESRLSFRNVPVQG-------QHRFQPRFTRGP--------AVQHRDGSQVRKGQALEAVKPDLSPELGMIFNKQDQEVRDMGYHKHAFNVLISNRLGYHRDVPDTRTDKCRDR--AYSVSLPTASIVICFFNEAFSALLRTVHSVLDRTPNYLLHEIILVDDHSELDDLKEDLDSYVQQHLQ-KKVKVVRNEKREGLIRGRMIGASHATGEVLVFLDSHCEVNEAWLQPLLTPIKENRKTVVCPVIDIISADTLVYTPSPIVRGGFNWGLHFKWDPVPMSELNSPDGA---IRSPTMAGGLFAMDRNYFYELGQYDRGMDIWGGENLEISFRIWMCGGQLLIVPCSRVGHIFRKRRPYGSPGGQDTMAHNSLRLAHVWMDDYKEQYFALRPELRNRDYGDISERVSIRKRLQCHSFKWYLDNIYPEMQVSSP-HKPQQ--PVFINKGLKRPKVLQRGRLRNLLADKCLVAQGRPSQ----KGGAVVVKDCDPQDPEQEWAYDEEHELVLAGLLCLDMSEIRSSDPPRLMKCHGSGGSQQWTLGK--KNWLYQVSVGQCLAVGDPLSIKGYVSMAICDDSRSQ--QWQLEG---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MVS5-1", "uniprot_id": "GLT35_DROME", "id": "Q8MVS5-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 35A", "aln": "MMQIKRLLCKSCGLGTLLVAVVW-LLALLFYSHSLRSSIRSAGWRIDEGNATPRAELSYQARVTVGCTP------NASITTGESPAAPKPPSD--PEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLRARLKYDNLRYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFEYTPSPLVRGGFNWGLHFRWENLPEGTLKVPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKHEKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELHVPGEESKKSAAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCR-RTPNQLWYETEKAEIVLDKLLCLEASG---DAQVTVNKCHEMLGDQQWRHTRNANSPVYNMAKGTCLRAAAPTTG-ALISLDLCSKSNGAGGSWDIVQLKKPTEAEGRAKEARNSDKAL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * *:.:..* :* ::::. * . . :. : .*.* * .. : . . **:: *::*: :**:**::**** *:*:.:* .* :**** * : . .** **:*:**:** :*:*::::*::*** :**:******* *:: :*: .*. :: * ::: ::* :******.*:*** .*.*:******** *** **:*** * .: *:. ****:*.***: *:.**:***********:*: :* . * .:. ::**********::*:** .**:** .********:***** * *** : *:*************** ** * :** :*********:*:**: *: . :. .:*:**:*:.:*::* *:.* ***.*:***:::.. : . *:: :: . : :* :: * .. . : **. : :: * * * * *. *::* ****: * . : *** *.*** : :. :*::: * ** . . :.: :*. * . .* : ", "identical_positions": 227, "similar_positions": 175, "identity": "35.14%" }, { "cls_id": "homologset.agr.MGI:2444393", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59268-1", "uniprot_id": "ZDHC9_MOUSE", "id": "P59268-1", "name": "Palmitoyltransferase ZDHHC9", "aln": "----------------------------------MSVMVVRKKVT--RKWEKLP--GRNTFCCDGRVMMAR-QKGIFYLTLFLILGTCTLFFAFECRYLAVQLS--PAIPVFAAMLFLFSMATLLRTSFSDPGVIPRALPDEAAFIEMEIEATNGAVPQGQRPPPRIKNFQINNQIVKLKYCYTCKIFRPPRASHCSICDNCVERFDHHCPWVGNCVGKRNYRYFYLFILSLSLLTIYVFAFNIVYVALKS-LKIGFLETLKETPGTVLEVLICFFTLWSVVGLTGFHTFLVALNQTTNEDIKGSWTGKN-------RVQNPYSHGNIVKNCCEVLCGPLPPSVLDRRGILPLE-----ESGSRP--------------PSTQETSSS--LLP---------------QSPASTEHMNSNEMAEDTSIPE-----------------EMPPPE---------------------------PPEPPQEASEAEK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y397-1", "uniprot_id": "ZDHC9_HUMAN", "id": "Q9Y397-1", "name": "Palmitoyltransferase ZDHHC9", "aln": "----------------------------------MSVMVVRKKVT--RKWEKLP--GRNTFCCDGRVMMAR-QKGIFYLTLFLILGTCTLFFAFECRYLAVQLS--PAIPVFAAMLFLFSMATLLRTSFSDPGVIPRALPDEAAFIEMEIEATNGAVPQGQRPPPRIKNFQINNQIVKLKYCYTCKIFRPPRASHCSICDNCVERFDHHCPWVGNCVGKRNYRYFYLFILSLSLLTIYVFAFNIVYVALKS-LKIGFLETLKETPGTVLEVLICFFTLWSVVGLTGFHTFLVALNQTTNEDIKGSWTGKN-------RVQNPYSHGNIVKNCCEVLCGPLPPSVLDRRGILPLE-----ESGSRP--------------PSTQETSSS--LLP---------------QSPAPTEHLNSNEMPEDSSTPE-----------------EMPPPE---------------------------PPEPPQEAAEAEK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R013-1", "uniprot_id": "ZDHC9_DANRE", "id": "F1R013-1", "name": "Palmitoyltransferase ZDHHC9", "aln": "----------------------------------MSAVMITRKIT--RKWEKLP--GKNTFCCDGRVMMAR-QKGVFYLTLFLIVGTCSLFFAFECPYLAVHLS--PAIPVFAVLLFVFVMAMLLRTSFSDPGVLPRALPEEANFIEMEIEAANGNVLAGQRPPPRIKNVQINNQIVKLKYCYTCKIFRPPRASHCSICDNCVDRFDHHCPWVGNCVGKRNYRYFYLFTLSLSLLTIYIFAFDIVHVVLRS-VDSGFVNTLKETPGTVLEVLVCFFTLWSVVGLTGFHTYLISLNQTTNEDIKGSWSGKN-------RVQNPYSHKNIIKNCCEVLCGPTYPSVLDRRGLMLED-----SCSSAPSNGATTVPVNKSSNPATQTTKSSAPLIPNE-------------HTPDEAKPSICSGTQKSSSSPK-----------------EEKPSS---------------------------PISPNAVAPAVIKESTH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2VEY9-1", "uniprot_id": "APP_DROME", "id": "A2VEY9-1", "name": "Palmitoyltransferase app", "aln": "--------------------------MNLLCCCCCSNMAPNQRVT--RKWELFA--GRNKFYCDGLLMSAP-HTGVFYLTCILITGTSALFFAFDCPFLADSIN--PAIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTHLVLLMKKEHEVFNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFSSKGGP-----RTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHALS------DVLSASHMVTTSQPMMGGLGGGGIGGAGGGISIGGAELKPRFYDESNPSSSTLEGNGGAINGHGNGHGNGFDHPPPSYDLVQNGNSNSLAQLVDNEIPLVQMDIPAYTHQTATQARQYRHRHHKQRQICNGGTVSYENQLANASSEDELDDPDVVVVGSPEVVAAVAAIASNKAREMRNRSGSYSNLFDADFEAALVNSSLADNHVRGEGASSSGKPSAGAALLAAAISGKTENMYSNVLPVDNDTDPADSTLHVYSNIIDERKQQEQANNVLSSTLLCDDLDLDDPVSASCHVKRKSLGDGAEQVKSAERLRMLHDNTMIDTALDLDSLDGSSMGNNSQSCLVKSGKPNATSVTTNVAIV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06551-1", "uniprot_id": "ERFB_YEAST", "id": "Q06551-1", "name": "Palmitoyltransferase ERF2", "aln": "MALVSRRSTRSESTSITKEEHTGEGSLTKLFFRWLVTLEGDQDINDGKGYISLPNVSNYIFFLGGRFRTVKGAKPLWLGVLLAIVCPMVLFSIFEAHKLWHTQNGYKVLVIFFYYFWVITLASFIRTATSDPGVLPRN-------IHLSQLRNNYQIPQEYYNLITLPTHSSISKDITIKYCPSCRIWRPPRSSHCSTCNVCVMVHDHHCIWVNNCIGKRNYRFFLIFLLGAILSSVILLTNCAIHIARES-------GGPRDCPVAILLLCYAGLTLWYPAILFTYHIFMAGNQQTTREFLKGIGSKKNPVFHRVVKEENIYNKGSFLKNMGHLMLEPRGPSFVSAR-------------------------------------------------------------KPHEAGDWRFMDLS---------------------------------------------------------PAHSFEKIQKI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. : : :. .. * .* . . . :: . : * . ** *:. * . .: :. ::.: :: ::**: :****:** *. . * .: :.:*** :*:*:****:**** *: ** .**** **.**:******:* :* :. : :: ::: ::. : * ::: : . :::* * :* :: :***.* :** : *. : :* *.: .: * .:: * **.:. * * . ", "identical_positions": 68, "similar_positions": 95, "identity": "9.23%" }, { "cls_id": "homologset.agr.MGI:2444398", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LRC7-1", "uniprot_id": "F1LRC7_RAT", "id": "F1LRC7-1", "name": "", "aln": "MSVPETPGEMERAAEEERPPPPTGEGNEEE-VVAAAARASGLVRRRSASSVDDEEE-EAAAETTVVAGGGCKEQELTYELQQGYRILGEFLQEKHRGLTAPFLQPLGGVAAGEEEVAEGRRSGGRGSRVPPQQPGQGMCLLKMEEKFSSGQYRGITEFVADFRLMLETCYRLHGVDHWISKQGQKLEMLLEQKLALLSRHLREKTTIAVTSRGYYGLEEEKGTACTSTRRRSTPRSLAGLTSGVFESIMVQVLRQEEQLRAKEEKRLREQERKEAEEACQKEVEEWERKLLAQAAPACMENMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRPTLHRRPTLPYRTWEAVLRQKVRQWYTAVGQTENPGNCAEKLGLCPQFFKVLGEVNPLEERPFHELPFYQKVWLLKGLCDFVYETQKEVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQRPFQAPEFPVPPIKVKRVPRIKLEKFKCDYVNTSNGEHRCNREGLPLTFKKEQEIDFDPAYCPAKMNFDNHDITVEVEVKANCDIKVHRPCEIEKTDCCKENLQKPRSPGEVTGFGEPLSPGEIRFIENQEKYGEASKIKTESNPLKENALKSCQIHINGSHIDHPDINCRKAVRDILLEHSLQSHKKLKLTKMRAKKKKKKKKKLKDVLSENLQRKREGLHSLPFKSYKPEIQSKLLIIKKKGKHKKHKSGKKSISKKAITKKRKTVTKSPAVPEFQLICTNLDELRELITKIENELKDLENSRKKSGRWYHRRQAVKELHSTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDDFRRQPDHGQFTRELWTTEESEGHPEREAPKAELSKSVDAAEPLDSLDKEREDSDDMKLSDIGFPMARSKLLKKELPSKDTVKTLPKALKRQSKQSSCPDDSAEELSPRKRARLSTSEPSAENLDVEMPIDCLSECKPAELPFQESFASKDSVPVSTLQKGTKPIQALLAKNIGNKVTLTNQLPPSTGRSVPAVEKPAPSPAETSPIKPALTCLTSTKGPLQMVYKIPCGQWLPVDLHSSSVKIQMQPVVDSKTGEKIMQQVLILPKNFVIQHKEGKAVAKEIAAPQQKGAE-HCSPCPQTTSVNCSLVSVPVTS---VCTQLPDTVLNKTVTLSSNVS-ARSQPLSPVTSVSNVLISPVKTSQSEAGKVKSTVSSNTFPQSNTSPTISSTVQPLLPATTLNEFTDPGSSLPCFSQQTVDSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKVQTNPEQNSPNSLSSSSVFTFAPQFQAFLVPKS-TSCPTSSQVAGVTATSSLPSFSQAPTSMSITCGSHPPVGKNLKSTVGQTFSSGYAGPMIEKMPCMPSSPLKPSISSSSLLPPPTNSSVSVISISAGNFGQSNASVIHTSTKPQQVDCITKSYPVTGSEATTAINGDVL--------SVVSAPPLPPPGSAPSAAVAPAPASAGASTQKVVFINAPAPSGTSSSALVAESLKQTLPSPLSKTYVKNPEQPQIVLIPSTVGAPRKVNSSPAVSQIKDVKIGLNIGQAIINPPGNLPAVSSINILQSVMPKAEDKSNKGCISPISPSSNSVPASSNIVSQTLPPASES----ARAANTFSGIAANVPLSSLSVTSSPASVGTRPPVLVSGNDTSSRIMPVLSNRLCTSNLGNTVAISTVKTGHLASSVLISTTQPAVSPRCLTSALQIPVTVALPPPVTTSPKIINTAPQSAAVPGATHPVSLPKKQSRTSLQFQSPGTTATVPTNANTTKPPAEFSSPSPSPGKIVSISNVPSVPNQHVPPSLVKTTLSNNSLAGGSAIHTCSPPSNITGLAGAPFTEPCIQQKIVINTSTPLAPGTQIMMNGARFIVPPQGLGAGSHVLLIATNPKYGPPLLLNSGQSILATPVDNPVQKIIQTSNSSLSGQPLKHSVRNSTKIVNSFGSPSSLSAVHTAPHIVNTPAKACVPP-APPAPLTSVIKASPAALLAKTSLVSAVSPSNPPLPSSTSVFHLDTSVKKLLVSPEGAILNTINTPAAKAPSLSSSLP-PVVTASQNPAPVFPAFPSSGLEKPDTAAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "H3BKP8-1", "uniprot_id": "H3BKP8_MOUSE", "id": "H3BKP8-1", "name": "", "aln": "MSVPEPPGEMERAAEEERPPPPTGEGNEEEVVVAAAARASGLVRRRSASSVDEEEE-AAASETTVVAGGGCKEQELTYELQQGYRILGEFLQEKHRGLTAPFLQPLGGVAAGEEEVAEGRRSGGRGSRVPPQQPSQGMCLLKMEEKFSSGQYRGITEFVADFRLMLETCYRLHGVDHWISKQGQKLEMLLEQKLALLS-------------------------------------------------------------------RLREQERKEAEEACQKEVEEWERKLLAQAAPACMENMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRPTLHRRPTLPYRTWEAVLRQKVQQWYTAVGQTENPDNCAEKLGLCPQFFKVLGEVNPLEERPFHELPFYQKVWLLKGLCDFVYETQKEVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQRPFQAPEFPVPPIKVKRVPRIKLEKFKCDYANTSNGEHRCTKEGLPLAFKKEQEIDFDPACCPTKMNFDNHDITLEMEVKSNCDIKVHRPCEIEKTDCCKENLQKPRSPGEVTGFGEPLSPGEIRFIENQEKYGEASKIKTESNPLKENALKSCQIHINGSHIDHPDINCHKVVRDILLEHSLQSHKKLKLTKMRAKKKKKKKKKLKDVLNENLQRKREGLHSLPFKSYKPEIQNKLLIIKKKGKHKKHKSGKKSISKKAITKKRKTVTKSPAVPEFQLICTNLDELRELITKIENELKDLENSRKKSGKWYHRRQAVKELHSTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDDFRRQPDHGQFTRELWATDECEGNPEREAPKAEVSKSVDAAEPLDTLEKEQEGSDDMKLSEIGFPMARSKLLKKELPSKDIVKTLPKTLKRQSKQSSYLDDSTKELSPRKKAKLSTNETSVENLEVNMQIECLKESKPPELPTPESFASKASVPVSTLQKGTKPIQALLAKNIGNKVTLTNQLPPSTGRSVPAVEKPALSPEDTSPLKPALTCLTSTKGPLQMVYKMPCGQWLPVDLHSSSVKIQMQPMVDSKTGEKIMQQVLILPKNFVIQHKEGKAVEKEIAAPQQKGPE-HCSPGPQ-TSASCSLVSVPVTS---VSTQLPNTVLSKTSTPSSNVS-ARSQPLSPVASVSNALTSPVKTSQSEAGKVKSTASSTTLPQPHTSPTISSTVQPLLPATTLNESTDPGSSIPCFSQQTVDSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKVQTNPEQNSPNSLSSSSVFTFTPQFQAFLVPKS-TSCSASSQVAGVTTTSSLPSFSQASTSVSISCGFHPPMGKNLKSTQGQTLSSGYVGPMIEKTSYMPSSPLKPSVSSSSLLPSTTNSSVSVISISTGNFGQTNTNVIHTSTKPQQVDCITKSYPVTRSEATTAVNGDVLGETPGQKLMLVSAPSGLPSGSVPSVNTAPEPTSAGVSTQKVVFINAPVPGGASSSAIVAESLRQSLPSPLNKTYIKNPEQPQIVLIPSTVGAPIKINSSPTVSQIKDVKIGLNIGQAIINPPGNLPAMSSINILQSVMPKGEDKSSKSCISPISPNSNSAPASSNIVNHSLPAASES----ARTANTFSGIGASVPLSSLSVASSPASAGTRPPVLVSGNDTSSRIMPVLSNRLCPSNLGNTVAISTVKTGHLASSVLISTTQPTVSPKCLTPALQIPVTVALPTPVTTSPKIINTVPQSATIPGATRPVSLSKRQSQTSLQFQSPGTTTIVPTNANTNKPPAELS-PSASPGKIVNISNVTSMPNQHMSPSLVKSTLGNNSIAGGSAIHTCSPPSNITSLAGAPFSEPCIQQKIVINTSTPLAPGTQIMMNGARFIVPPQGLGAGSHVLLISTNPKYGPPLVLNSGQSILATPVDNPVQKIIQTSNSSLSGQPLKPSVRNSPKTVNSLGSPSSLSAVHTPPHIINTPAKVCVPP-APPAALTSVIKSSPATLLAKTSLVSAISSSNPPLPSSTSVLHLDTSVKKLLVSPEGAILNTINTAAAKVSSLPSPLP-PVVSASQNPASVFPAFPSSALEKPDTAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5HYC2-1", "uniprot_id": "BRD10_HUMAN", "id": "Q5HYC2-1", "name": "Uncharacterized bromodomain-containing protein 10", "aln": "MSVPGTPGAMEPAGEEERPPP-AAEGEDDEEEVAAAAQTSGPAHGRSASSLEDADDQEEEMEAMVIGGGCCKEQELTYELQQGYRILGEFLQEKHRGLTAPFLQPLGGVATAEEEVAEGPRSGGRGGRAFPQQPGQGMCLLQMEEKFASGQYGGITEFVADFRLMLETCYRLHGVDHWISKQGQKLEMMLEQKLALLSRHLREKTTIAVTSRGYYGLEDEKGTACTSTRRRSTPRSLAGLTSGVFESIMVQVLRQEEQLRAKEEKRLREQERKEAEEASQKEIEEWERKLLAQAAPTCMETMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRPTLHRRPTLPYRTWEAALRQKVQQWYTAVGQTENPDNCAEKLGLCPQFFKVLGEVNPLEEKPFHELPFYQKVWLLKGLCDFVYETQKEVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQRPFQAPEFPIPPIKIQRVPRIKLEKLKCDYVSTSNGEHRCSRDSLPSSFKKEQENNFDPACCPAKMILDNHDISVEMGVKSNYEIRIRRPCEIKKTDCCKENLEKPRSPGEVTGFGEPLSPGEIRFIENQEKYGEASRIKIEPSPLKENTLKSCQIHVNGSHSDHPEINCHKVVRDILLEQSLQSHKKLKLTKMRAKKKKKKKKKLKDVLNENLQRKREGLHSLAFKSYKPEIQNKLLIIKKKAKHKKHKSGKKSVSKKAITKKRKTVIKSPTVPEFQLICTNLDELRELITKIENELKDLENSRKKSGKWYHRRQAVKELHSTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDDFRRQPDHDTFNRELWTTDEGEGDLGKDSPKGEISKSIDSTEPLDILEKDHFDSDDMKLSEIDFPMARSKLLKKELPSKDLPKTLLKTLKRQSKQTDYVDDSTKELSPRKKAKLSTNETTVENLESDVQIDCFSESKHTEPSFPESFASLDSVPVSTLQKGTKPIQALLAKNIGNKVTLTNQLPPSTGRNALAVEKPVLSPPEASPIKPALTCHTNTKGPLQMVYKMPCGQWLPIDLQNSSVKIQVQPMVDPKTGEKIMQQVLILPKNFVIQHKEGKAVAKEVPPLQQKGTEQHCSSFPQTTNINSSLASVFVNSPGTVSTQLPNTAFNKTITPLSNISSARPQPLSPVTSVSNLLTPSVKTSQSEAGKAKNAVSAATFSLPSASPTISSTGQPLSSTTTLNGSTNPGSSFNCFAQQTADSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKVQTNPDQNSPNTVSSSSVFTFAPQLQAFLVPKSTTSSSAFSPVAGTTTTSSLSPFSQTPTSVSIPASFAPSMGKNLKLTLGHTTGSGDLGHVIDKTSHMPSSPLKSSICSSTLLPSTTSSSVSVISISAANFGQNNANIIHTPTKQQQVDYITKSYPVTRSEATAATNGDVISGTPVQKLMLVSAPSILSSGNGTAINMTPALTSTGVSAQKLVFINAPVPSGTSTPTLVAESLKQTLPPPLHKAYVKTPEQPQIVLIPSTVGTPIKINSSPAVSQIKDVKIGLNIGQAIVNTSGTVPAIPSINILQNVTPKGEDKSSKGYILPLSTSGNSVPVSSNFVSQNITPVNESVVSSARAVNVLSVTGANLSLGSFPVTSASASAGAQPPVLVSGNDTSSRIMPILSNRLCSSSLGNTVAISTVKTGHLASSVLISTTQPVVSPKCLTSALQIPVTVALPTPATTSPKIINTVPHSAAVPGATRSVSISKRQSRTSLQFHSPGISTTVPTNVNTNKPQTELSSLSTSPGKITNTSNFASLPNQ---QALVK-TPSYSSAPGGTTIHTASAPSNVTSLVGSQFSEPCIQQKIVINTSTPLAPGTQIMINGTRFIVPPQGLGAGSHVLLISTNPKYGAPLVLNSGQGIQSTPIDNSAQKITLASNNSLSGQPLQHPLRSPTKFINSFGNASSIPTVHTSPQLINTTAKVPVPPPVPTVSLTSVIKS-PATLLAKTSLVSAICPSNPPLPSSTSVFHLDPPVKKLLVSPEGAILNTINTPASKVSSLSPSLSQIVVSASRSPASVFPAFQSSGLEKPDRAAS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** .** ** *.******* :.**:::* *****::** .: *****::: :: *: *:.** ****************************************:.******* ******.*. ****.******:*****:**** ***********************************:********* *************.***:*************:***.***********************************************************************.*****:************.************************:*******************************************************************************:****::*********:****..********.::.** :****** :**** **:** :*****::*: **:* :*:::*****:*********:*********************************:** *..*****:*******:**** ***:***:*.*******:*****************************.*************.*********.********.***********:************ ***:************************************:*****************************************************. *.****:*:* **. :::**.*:***:*::**** *:*:: .*******:*.***************** *** *:*******:. ***::******:*:***.*.:.***: :: *:*:.*.* .* . ***** **************************************.. *****. ** ::**:****** *.**********:*******:**:.******:**:**.*************************** **:.. ****.* ***. ** *. ..**.** *.* *.****:*.:.** * **:* **.******:**** * ..**********.*.:.*: *:. . :******* *** .:**** *:****: **:***.**************************************:*****::********:**:******** **..: * ***.*:****..***:.**:**... *.:***** * *:* .** * :*:* . *******.*:.**:***..*.*********:.****.*:.:***.** **** ******** ****:* ****: :****. ..*. .: :* :*:*.*:**:******.*.*:*:.::*****:*:**.** *:*:*.**************:* *:****:*****************:*..*.:**:.******.* **.****.*. * *:*...**.*.***:*.:.:....** **:.*.:* .*.:.*.*:.*:*:.**.*::****************:******.*.**************************.***:***.***********.*.*********.*:**::****:.**:.*:**:*****:*** :: ****.**.** :*:* *.*****.. **..*:*** :*** * . .* .**::***.*.***:*.*.*: *:***********************:**:******************:******.**:*****.* :**:**..*** :**.*******: .:*...* :**:*..**:.:***.*:::**.**. *** .*...******: **:**********:..***********:***..******************.*:*..**...*. **:**:.**.***** **.***** ***", "identical_positions": 1519, "similar_positions": 376, "identity": "72.02%" }, { "cls_id": "homologset.agr.MGI:2444401", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P4T2-1", "uniprot_id": "U520_MOUSE", "id": "Q6P4T2-1", "name": "U5 small nuclear ribonucleoprotein 200 kDa helicase", "aln": "------MADVTARSLQYEYKANSNLVLQADRSLIDR---TRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDMNKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALG-DQPRDILCGAADEVLAVLK-NEKLRD---KERRREIDLLLGQ-TDDTRYHVLVNLGKKITDYGGDKE--------IQNMDDNIDET----YGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMSSKKKD--LHPRDIDAFWLQRQLS--RFYDDAIVSQKKADEVLEILKTASDD-RECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEPEKERIVGKMEADPELSKFLYQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEG--FKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHIN-MDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIVLDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGK-NQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLN-HNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEK---VHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEP----LPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTG-ETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIG-GENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKK-PVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAP----------------LNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNP-----KFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEE-VTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTL-QQKAKVKLDFVAPATGGHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LNJ2-1", "uniprot_id": "U520_RAT", "id": "F1LNJ2-1", "name": "U5 small nuclear ribonucleoprotein 200 kDa helicase", "aln": "------MADVTARSLQYEYKANSNLVLQADRSLIDR---TRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALG-DQPRDILCGAADEVLAVLK-NEKLRD---KERRREIDLLLGQ-TDDTRYHVLVNLGKKITDYGGDKE--------IQNMDDNIDET----YGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMSSKKKD--LHPRDIDAFWLQRQLS--RFYDDAIVSQKKADEVLEILKTASDD-RECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFLYQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEG--FKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHIN-MDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIVLDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGK-NQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLN-HNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKARLVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEP----LPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTG-ETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIG-GENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKK-PVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAP----------------LNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNP-----KFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEE-VTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTL-QQKAKVKLDFVAPATGGHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75643-1", "uniprot_id": "U520_HUMAN", "id": "O75643-1", "name": "U5 small nuclear ribonucleoprotein 200 kDa helicase", "aln": "------MADVTARSLQYEYKANSNLVLQADRSLIDR---TRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALG-DQPRDILCGAADEVLAVLK-NEKLRD---KERRKEIDLLLGQ-TDDTRYHVLVNLGKKITDYGGDKE--------IQNMDDNIDET----YGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMSSKKKD--LHPRDIDAFWLQRQLS--RFYDDAIVSQKKADEVLEILKTASDD-RECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFLYQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEG--FKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHIN-MDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGK-NQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLN-HNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEK---VHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEP----LPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTG-ETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIG-GENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKK-PVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAP----------------LNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNP-----KFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEE-VTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTL-QQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S754-1", "uniprot_id": "B0S754_DANRE", "id": "B0S754-1", "name": "U5 small nuclear ribonucleoprotein 200 kDa helicase", "aln": "------MADVTARSLQYEYKANSNLVLQADRSLIDR---TRRDEPTGEVLSLVGKLEGTKMGDRSQRTKPQMLEERRAKRRKRDEDRHDINKMKGFTLLSEGIDEMVGIVYKPKTKETRETYEILLSFIQAALG-DQPRDILCGAADEVLAVLK-NDKMRD---KERRREVEQLLGP-TDDTRYHVLVNLGKKISDYGGDKE--------LQNMDDNIDET----YGVNVQFESDEEEGDEDQYGEVRDEGSDD-SEGEEADESSTLTANLGNTGDVMMTKKKD--LHPRDIDAFWLQRQLS--RFYNDAIVSQKKADEVLEILKTASDD-RECENQLVLLLGFNTFDFIKVLRQHRRMILYCTMLASAQSEAEKEKIINKMEADQDLSKVLYQLQETEKEDIIREERSRRERMRKSRVD-DLESMDIDHG-ESVSSRQLLDLEDLTFTQGSHFMANKRCQLPDGSFRKQRKGYEEVHVPALKPKPFGDEETLVGIEKLPKYAQAGFEG--FKSLNRIQSKLFKTTMETDENLLVCAPTGAGKTNVALMAMLREIGKHIN-MDGTINVADFKIIYIAPMRSLVQEMVGSFGKRLASYGIIVSELTGDHQLCKEEINATQIIVCTPEKWDIITRKGGERTYTQLVRLIIIDEIHLLHDDRGPVLESLIARTIRNVELTQEDVRLIGLSATLPNYEDVATCLRVDPSKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGK-NQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDSKGEGILITSHGELQYYLSLLNQQLPIESQMVGKLADMLNAEIVLGNVQNAKDAVNWLGYTYLYVRMLRNPTLYGVSHDDRSIDPLLERRRMDLVHTAATVLEKNNLVKYDKRSGSFQVTDLGRIASHFYITHESIMTYNQLLKPTLSEIELFRVFSLSSEFRNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAYISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLSRGWAQLTDKTLNLCKMIDKRMWQSMSPLRQFRKLPEEVIKKIEKKNFPFERLYDLN-HNEIGELIRMPKMGKTIHKYVHQFPKLDLAVHLQPITRSTLKVELTITPDFQWDDK---IHGSSEAFWILVEDVDSEVVLHHEYFLLKAKYAQDEHLVTFFVPVFEP----LPPQYFIRIASDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNGAFESLYQN-FPFFNPIQTQVFNAVYNSDDNVFVGAPTGSGKTICAEFAILRMLLHNAEGRCVYITPMEALAEQVFLDWHQKFQENLNKKVVLLTG-ETSTDLKLLGKGDIIVSTPDKWDILSRRWKQRKNVQNVSLFIIDEVHLIG-GDNGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSTTATFNFHPNVRPVPLELHIQGFNVSHTQTRLLSMAKPVYHAIMKHSPSK-PVLVFVPSRRQTRLTAIDILTFCAADVVPQRFLHSTEKDLVPFMENLSDVTLKETLSNGVGYLHEGLSPTERRIVEHLFTSGAIQVVVASRSLCWGTNISAHLVIVMDTQYYNGKIHAYVDYPIYDVLQMVGKANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCLHDHFNAEIVTKTVENKQDAVDYLTWTFLYRRMTQNPNYYNLQGMSHRHLSDHLSELVENTLQDLEQSKCISIEDEMDVAP----------------LNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYKNIPIRHHEDTLLRQLAQKVPHKLNNP-----KFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAVRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLRQLPHFTSELIKRCTDKGVESIFDIMEMEDEDRTGLLQLSDVQVADVARFCNRYPNIELSYEVVDKDDIKSGSPVVVQVQLEREEE-VTGPVIAPLFPQKREEGWWVVIGDPKSNSLISIKRLTL-QQKAKVKLDFVAPVVGVHNYTLYFMSDAYMGCDQEYKFSTEVKEADSEGDSDSD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUV9-1", "uniprot_id": "U520_DROME", "id": "Q9VUV9-1", "name": "U5 small nuclear ribonucleoprotein 200 kDa helicase", "aln": "------MADAAARQLQYEYKANSNLVLQADVRLIER---PRRDEATGEVCSLVGKLDGTRMGDRYQRTKPEKTEERKVKRQKRDEAQYDFERMKGATLLSEGIDEMVGIVYRPKTQETRQTYEVLLSFIQEALG-DQPRDILCGAADEILAVLK-NDRLKD---RERKKDIDSLLGA-VTDERFALLVNLGKKITDFGSDAVNA---LTAAPNNEEQIDET----YGINVQFEESEEESDNDMYGEIRDDDAQD--EGEEARIDHTLHAENLANEEAANNVKKERSLHPLDIDAYWLQRCLS--KFYKDAMVSQSKAADVLKILKDAADD-RDCENQLVLLLGYDCFDFIKQLKLNRQMVLYCTMLASAQTDSERQRIREKMRGNSALAKILRQLDTGKSEDQEEGEARGSKRGKG-----DAEDGGAAAAGQVAGVRQLLELEEMAFTQGSHFMANKRCQLPDGSYRKQRKGYEEVHVPALKPVPFDANEELQPVDKLPKYVQPVFEG--FKTLNRIQSRLYKAALDSDENMLLCAPTGAGKTNVALLTMMREIGKHIN-EDGTINAQDFKIIYVAPMKSLVQEMVGNFGRRLACYNLTVSELTGDHQLTREQIAATQVIVCTPEKWDIITRKGGERTFVSLVRLVIIDEIHLLHDERGPVLEALVARTIRNIETTQEEVRLVGLSATLPNYQDVATFLRVKPDKGLFYFDNSYRPVSLEQQYIGVTEKKALKRFQVMNEIVYEKTMEHAGR-NQVLVFVHSRKETGKTARAVRDMCLEQDTLGSFLKEGSASMEVLRTEAEQVKNTELKELLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYNPEKGRWVELSALDVLQMLGRAGRPQYDTKGEGILITNHSELQFYLSLLNQQLPIESQFISKLPDMLNAEIVLGTVQHLQDAVNWLGYTYLYIRMLRNPTLYGVSHDAIKADPLLEQHRADLLHTAACCLERSGLIKYDRKTGHFQVTDLGRIASHYYLTHETMLTYNQLLKQTLSEIELFRVFSLSSEFRHISVREEEKLELQKLMERVPIPIKESIEEHSAKVNVLLQAYISQLKLEGFALMSDMVFITQSAARLMRAIFEIVLTRGWAQLADKTLTLCKMIDRRMWQSMTPLRQFKKMPDEIAKKLEKKHFPWGRLYDLE-PHELGELIRVPKLGKTIHKFVHQFPKLELSTHIQPITRGTLRVELTITPDFQWDEK---VHGQSEGFWVLIEDVDSELILHHEFFLLKQKYSQDEHQLKFFVPVFEP----LPPQYFLRIVSDRWIGAETQLPVSFRHLILPEKNMPPTELLDLQPLPISALRQPKFESFYSQRFPQFNPIQTQVFNAVYNSDENVFVGAPTGSGKMTIAEFAIMRLFTTQSDARCVYLVSEEALADLVFADWHSKFGS-LDIKVVKLTG-ETGTDLKLIAKGQLVITTADKWDVLSRRWKQRKNVQLVNLFIVDELQLVG-GEEGPVLEIVCSRMRYISSQIEKQIRIVALSASLTDARDVAQWLGCNPNATFNFHPSVRPIPLELHIQGYNVTHNATRIATMSKPVYNAILKYSAHK-PVIVFVSSRKQARLTAIDVLTYAASDLQPNRFFHAEEEDIKPFLERMTDKTLKETLAQGVAYLHEGLSASDHRLVEQLFDSGAVQVAVISRDLCWGMSISAHLVIIMDTQFYNGKNHSYEDYPITDVLQMIGRANRPNEDADAKCVLMCQSSKKDFFKKFINEPLPIESHLDHRMHDHFNAEVVTKTIENKQDAVDYLTWTFLYRRLTQNPNYYNLQGVTHRHLSDHLSELVENTLSDLEQSKCISVEDDMDTLP----------------LNLGMIAAYYYINYTTIELFSLSLNSKTKVRGLLEIISSAAEYEDVVVRHHEEQVLRTLSQRLPNKLTGPNETAPKFNDPHIKTNLLLQAHLSRLQLGPELQGDTEQILSKAIRLIQACVDVLSSNGWLSPAVAAMELAQMVTQAMWSKDSYLKQLPHFSPEIVKRCTEKKIETVFDIMELEDEDRTRLLQLSDLQMADVARFCNRYPNIELNYEVVDKDRINSGSTVNVVVQLEREDE-VTGPVIAPFFPQKREEGWWVVIGDPKTNSLLSIKRLTL-QQKAKVKLDFVAPSPGKHDYTLYYMSDSYLGCDQEYKFSIEVGDFQSESESESD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32639-1", "uniprot_id": "BRR2_YEAST", "id": "P32639-1", "name": "Pre-mRNA-splicing helicase BRR2", "aln": "MTEHETKDKAKKIREIYRYDEMSNKVLKVDKRFMNTSQNPQRDAEISQPKSMSGRISAKDMGQGLCNNINKGLKENDVAVEKTGKSASLKKIQQHNTILNS--SSDFRLHYYPKDPSNVETYEQILQWVTEVLGNDIPHDLIIGTADIFIRQLKENEENEDGNIEERKEKIQHELGINIDSLKFNELVKLMKNITDYETHPDNSNKQAVAILADDEKSDEEEVTEMSNNANVLGGEINDNEDDDEEYDYNDVEVNSKKKNKRALPNIENDIIKLSDSKTSNIES--VPIYSIDEFFLQRKLRSELGYKDTSVIQDLSEKILNDIETLEHNPVALEQKLVDLLKFENISLAEFILKNRSTIFWGIRLAKS-TENEIPNLIEKMVAK-GLNDLVEQYKFRETTHSKRELDSGDDQPQSS------EAKRTKFSNPAIPP--VIDLEKIKFDESSKLMTVTKVSLPEGSFKRVKPQYDEIHIPAPSKPVIDY--ELKEITSLPDWCQEAFPSSETTSLNPIQSKVFHAAFEGDSNMLICAPTGSGKTNIALLTVLKALSHHYNPKTKKLNLSAFKIVYIAPLKALVQEQVREFQRRLAFLGIKVAELTGDSRLSRKQIDETQVLVSTPEKWDITTRNSNNLAIVELVRLLIIDEIHLLHDDRGPVLESIVARTFWASKYGQEYPRIIGLSATLPNYEDVGRFLRV-PKEGLFYFDSSFRPCPLSQQFCGIKERNSLKKLKAMNDACYEKVLESINEGNQIIVFVHSRKETSRTATWLKNKFAEENITHKLTKNDAGSKQILKTEAANVLDPSLRKLIESGIGTHHAGLTRSDRSLSEDLFADGLLQVLVCTATLAWGVNLPAHTVIIKGTDVYSPEKGSWEQLSPQDVLQMLGRAGRPRYDTFGEGIIITDQSNVQYYLSVLNQQLPIESQFVSKLVDNLNAEVVAGNIKCRNDAVNWLAYTYLYVRMLASPMLYKVP--DISSDGQLKKFRESLVHSALCILKEQELVLYDAENDVIEATDLGNIASSFYINHASMDVYNRELDEHTTQIDLFRIFSMSEEFKYVSVRYEEKRELKQLLEKAPIPIREDIDDPLAKVNVLLQSYFSQLKFEGFALNSDIVFIHQNAGRLLRAMFEICLKRGWGHPTRMLLNLCKSATTKMWPTNCPLRQFKTCPVEVIKRLEASTVPWGDYLQLETPAEVGRAIRSEKYGKQVYDLLKRFPKMSVTCNAQPITRSVMRFNIEIIADWIWDMN---VHGSLEPFLLMLEDTDGDSILYYDVLFITPDIVGHEFTLSFTYELKQHNQNNLPPNFFLTLISENWWHSEFEIPVSFNGFKLPKKFPPPTPLLENISISTSELGNDDFS--EVFEFKTFNKIQSQVFESLYNSNDSVFVGSGKGTGKTAMAELALLNHWRQN-KGRAVYINPSGEKIDFLLSDWNKRFSHLAGGKIINKLGNDPSLNLKLLAKSHVLLATPVQFELLSRRWRQRKNIQSLELMIYDDAHEISQGVYGAVYETLISRMIFIATQLEKKIRFVCLSNCLANARDFGEWAGMTKSNIYNFSPSERIEPLEINIQSFKDVEHISFNFSMLQMAFEASAAAAGNRNSSSVFLPSRKDCMEVASAFMKFSKA--IEWDMLNVEEEQIVPYIEKLTDGHLRAPLKHGVGILYKGMASNDERIVKRLYEYGAVSVLLISKD-CSAFACKTDEVIILGTNLYDGAEHKYMPYTINELLEMVGLASG-NDSMAGKVLILTSHNMKAYYKKFLIEPLPTESYLQYIIHDTLNNEIANSIIQSKQDCVDWFTYSYFYRRIHVNPSYYGVRDTSPHGISVFLSNLVETCLNDLVESSFIEIDDTEAEVTAEVNGGDDEATEIISTLSNGLIASHYGVSFFTIQSFVSSLSNTSTLKNMLYVLSTAVEFESVPLRKGDRALLVKLSKRLPLRFPEHT----SSGSVSFKVFLLLQAYFSRLELPVDFQNDLKDILEKVVPLINVVVDILSANGYLN-ATTAMDLAQMLIQGVWDVDNPLRQIPHFNNKILEKCKEINVETVYDIMALEDEERDEILTLTDSQLAQVAAFVNNYPNVELTYSLNNSDSLISGVKQKITIQLTRDVEPENLQVTSEKYPFDKLESWWLVLGEVSKKELYAIKKVTLNKETQQYELEFDTPTSGKHNLTIWCVCDSYLDADKELSFEINVK-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *.*. ** **:.* ::: .:** .: *: *::... **: .. : :*. . .* .: : : *:*.. .. . : * ** .. :*** :*.:: .** * *:*:: *:** .: ** *:. .* .**:..:: ** . :: **:* *:*:*: . ::: ** . *.:. .* :.::* * : : : .: .: : : . :. : .** ::*** * *.*: * *. : .:*: :: .: *::** ** :: :.: : : :* ::: **.: :: * .: ** .. * ..: * . :. . . .: : * . :::**.: * :.*::*: .: .**:**::: : *:*:*:** . :. * : .**.: * * . .:** ***:::::::: *.*:*:*****:****:**: ::: :.:* * .:* ***:*:**:::**** * .* :*** .: *:***** :* :::* **::*.******* **:..: : ..****:::********:******:::**:: : ** *::*********:**. *** * :******.*:** .*.* : *:.*::::*::: **: *** :* .. **::*********.:** ::: *:: : ::.:.* ::*:*** : : .*:.*: *:. ****:** **:* ****** :****.********************:**.**** * :*.. *:**********:**: ****:**.:.::*:***:**********::.** * ****:* *.:: :******.*:***:*** .* ** :. . * *.: * .*:*:* *... *: ** ... ::.*:**.*** :*:.: :: .**: *. ::*:***:**:*.**: ::** *** **::*:*:.***::*.*:: **:*****:::****:***** :*:*:: *.*.**:**:*** *.***.: : *.*** :** : *****:. * *: *::* . .*: :*: *:*. ** * ** ::. :: ***:.:: : *****..::.:: * .*: ** : :**. * * :::**.*.: :*::: :::. . .*. :.* : : ***::*: : *:.* .* ::****. : **:* *** **: .:. * * : *. * ** **:***:::***::.****: .*:** **:*::. . ..*.**: . : : ** .:* . *:: * :.. :***:.*..::::*. ::::*****:****:* :.*:: *: : :. * *.* * : *** :*::*:*: **:*.** .*::*:*...* * . . :** *. * ***::**.:: . : :* : .:.* : : . **:.**:: .* .:. . : ::: *::: *::*.::* *: .* :**. *::*::. :.*:*::*: **:.* : *:. * . :. **::.*: *:* * * *.* ::*:*:* *. :. .: ::: . . * ::***: **** **:*:: :** :* *:... ::.***.**::*::::***: **.**.::. : : :* .**:*** *.** :*. *.::* . *. *:**::* :.: **: * **. .:.::.:: ::*.*.*::.: :*: : :* *::::* :: . .. .*. *****::**::* ::*.* ::**.*.: **:. **:**:**:*. * :**:****: *.:*. *. *:*:***. : :::*.: :*:::*** :***:* :* *:* *:*:** * *.***:**.*.: :.* : ** : :** *: * . * : :* .: *.**:*:*: ..:.* :**::** ::. : :*:* :* * *: *:: :.*:*:..*:* .*. :* ", "identical_positions": 743, "similar_positions": 774, "identity": "33.65%" }, { "cls_id": "homologset.agr.MGI:2444403", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A3KFU9-1", "uniprot_id": "DISP3_MOUSE", "id": "A3KFU9-1", "name": "Protein dispatched homolog 3", "aln": "MDSEDDPLLQDVWLEEEQPE----DEACRGIPGPGLQSGAQG--CWRRWTLPSRPPTLGFWSTLGWAFTNPCCAGLVLFLGCSIPMVLSAFMFLYYPPLDIDISYNAFEIRNHEASQRFDALALALKSQFGSWGRNRRDLADFTSETLQRLISEQLQQLHLGNHSRPASRAPRSAP----------RDTVATQTSAANSSERRRREAPSPEGQVTNQS-----------------------------RARRGASRWDYSRTYVSANTQTHAHWRIELIFLARGDAERNIFTSERLVTIHEIERKIMDHPGFREFCWKPHEVLKDLPLGSYSYCSPPSSLMTYFFPTERGGKIYYDGMGQDLADIRGSLELAMTHPEFYWYVDEGLSVDNLKSSLLRSEILFGAPLPNYYSVDDRWEEQRAKFQSFVVTYVAMLAKQSTSKVQVLYGGTDLFDYEVRRTFNNDMLLAFISSSCIAALVYILTSCSVFLSFFGIASIGLSCLVALFLYHVVFGIQYLGILNGVAAFVIVGIGVDDVFVFINTYRQATHLEDPQLRMIHTIQTAGKATFFTSLTTAAAYAANVFSQIPAVHDFGLFMSLIVTCCWLAVLFTMPAALGLWSLYMAPLESSCQNSCHQKCGRKSSLHFPGDLFTAPERAGGGPAQGPLPYLDDDIPLLNVEDEPASLELGDVSLVSVHCEGLQPTPDANSRGQLLAQLQELLHHWVLWAAVKSRWVIVGLFASILILSLVFASRLRPASRAPLLFRPDTNIQVLLDLKYNLSAEGISCITCSGLFQEKPHSLQNNVRTSLEKKKRGSGVSWASRTETTAQESMSTVYISKVKSKGHPAVYRLSLNASLPAPWQAVSPGDGEVPSFQVYRAPFGDFTKKLTACMSTVGLLQAASPSRKWMVTALACDARRGWKFDFSFYVATKEQQHTRKLYFAQSHKPPFHGRLCVAPPGCLLSSSPDGPTKGFFYVPSDKVPKARISATFGFNPCVNTGCGKPAVRPLVDTGAMVFVVFGIIGLNRTQQMDNHVIGDPGSVIYDSSFDLFKEIGHLCRLCKAIAGNSELVKPGGAQCLPSGYSISSFLQMLHPECKELPEPNLLPGQLSHGAVGVKEGRVQWISMAFESTTYKGKSSFQTYSDYLRWESFLRQQLQTFPEGSALHRGFQTCEHWKQIFMEIIGVQSALYGLVLSLLICVAAVAVFTTHVLLLLPVLLSILGIVCLVVTIMYWSGWEMGAVEAISLSILVGSSVDYCVHLVEGYLLAGENLPPQLSQDPSSQRQWRTLEAVRHVGVAIVSSALTTVIATVPLFFCIIAPFAKFGKIVALNTGVSILYTLTVSTALLGIMAPGSFTRTRTSFLKALGAVLLAGALGLGACLVLLRSGYKIPLPSGATL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZW02-1", "uniprot_id": "D3ZW02_RAT", "id": "D3ZW02-1", "name": "Protein dispatched homolog 3", "aln": "MDSEDDPLLQDVWLEEEQQEEETSDEACRAVPGPGLHSGAQG--CWRRWTLPSRPPTLGFWSTLGWAFTNPCCAGLVLFLGCSIPMVLSAFMFLYYPPLDIDISYNAFEIRNHEASQRFDALALALKSQFGSWGRNRRDLADFTSETLQRLISEQLQQLHLGNHSRPASRAPRSDP----------RDTAATQRSATNTRERRRREAPPPEGQVANQS-----------------------------RARRGASRWDYSRTYVSANTQTHAHWRIELIFLARGDAERNIFTSERLVTIHEIERKIMDHPGFREFCWKPHEVLKDLPLGSYSYCSPPSSLMTYFFPTERGGKIYYDGMGQDLADIRGSLELAMTHPEFYWYVDEGLSVDNLKSSLLRSEILFGAPLPNYYSVDDRWEEQRAKFQSFVVTYVAMLAKQSTSKVQVLYGGTDLFDYEVRRTFNNDMLLAFISSSCIAALVYILTSCSVFLSFFGIASIGLSCLVALFLYHVVFGIQYLGILNGVAAFVIVGIGVDDVFVFINTYRQATHLEDPQLRMIHTIQTAGKATFFTSLTTAAAYAANVFSQIPAVHDFGLFMSLIVTCCWLAVLFTMPAALGLWSLYVAPLESSCQSSCHQKCGRKSSLHFPGDLFTAPERAGCGPAQGPLPYLDDDIPLLNVEDEPVSLELGDVSLVSVHCEGLQPTPDGNSRGQLLAQLQELLHRWVLWAAVKSRWVIVGLFASILILSLVFASRLRPASRAPLLFRPDTNIQVLLDLKYNLSAEGISCITCSGLFQEKPHSLQNNVRTSLEKKKRGSGVSWASRPETTAQESMSTVYISKVKSKGHPAVYRLSLNASLPAPWQAVSPGDGEVPSFQVYRAPFGDFTKKLTACMSTVGLLQAASPSRKWMVTALACDARRGWKFDFSFYVATKEQQHTRKLYFAQSHKPPFHGRLCVAPPGCLLSSSPDGPTKGFFYVPSDRVPKARISATFGFNPCVNTGCGKPAVRPLVDTGAMVFVVFGIIGINRTQQMDNHVIGDPGSVIYDSSFDLFKEIGHLCRLCKAIAGNSELVKPGGAQCLPSGYSISSFLQMLHPECKELPEPNLLPGQLSHGAVGVKEGRVQWISMAFESTTYKGKSSFQTYSDYLRWESFLRQQLQTFPEGSALRRGFQTCEHWKQIFMEIIGVQSALYGLVLSLLICVAAVAVFTTHVLLLLPVLLSILGIVCLVVTIMYWSGWEMGAVEAISLSILVGSSVDYCVHLVEGYLLAGENLPPQQAEDASSQRQWRTLEAVRHVGVAIVSSALTTVIATVPLFFCIIAPFAKFGKIVALNTGVSILYTLTVSTALLGIMAPGSFTRTRTSFLKALGAVLLAGALGLGTCLVLLRSGYKIPLPSGATL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P2K9-1", "uniprot_id": "DISP3_HUMAN", "id": "Q9P2K9-1", "name": "Protein dispatched homolog 3", "aln": "MDTEDDPLLQDVWLEEEQEEEEATGETFLGAQKPGPQPGAGGQCCWRHWPLASRPPASGFWSTLGWAFTNPCCAGLVLFLGCSIPMALSAFMFLYYPPLDIDISYNAFEIRNHEASQRFDALTLALKSQFGSWGRNRRDLADFTSETLQRLISEQLQQLHLGNRSRQASRAPRVIPAASLGGPGPYRDTSAAQKPTANRSGRLRRETPPLEDLAANQSEDPRNQRLSKNGRYQPSIPPHAAVAANQSRARRGASRWDYSRAYVSANTQTHAHWRIELIFLARGDAERNIFTSERLVTIHEIERKIMDHPGFREFCWKPHEVLKDLPLGSYSYCSPPSSLMTYFFPTERGGKIYYDGMGQDLADIRGSLELAMTHPEFYWYVDEGLSADNLKSSLLRSEILFGAPLPNYYSVDDRWEEQRAKFQSFVVTYVAMLAKQSTSKVQVLYGGTDLFDYEVRRTFNNDMLLAFISSSCIAALVYILTSCSVFLSFFGIASIGLSCLVALFLYHVVFGIQYLGILNGVAAFVIVGIGVDDVFVFINTYRQATHLEDPQLRMIHTVQTAGKATFFTSLTTAAAYAANVFSQIPAVHDFGLFMSLIVSCCWLAVLVTMPAALGLWSLYLAPLESSCQTSCHQNCSRKTSLHFPGDVFAAPEQVGGSPAQGPIPYLDDDIPLLEVEEEPVSLELGDVSLVSVSPEGLQPASNTGSRGHLIVQLQELLHHWVLWSAVKSRWVIVGLFVSILILSLVFASRLRPASRAPLLFRPDTNIQVLLDLKYNLSAEGISCITCSGLFQEKPHSLQNNIRTSLEKKRRGSGVPWASRPEATLQDFPGTVYISKVKSQGHPAVYRLSLNASLPAPWQAVSPGDGEVPSFQVYRAPFGNFTKKLTACMSTVGLLQAASPSRKWMLTTLACDAKRGWKFDFSFYVATKEQQHTRKLYFAQSHKPPFHGRVCMAPPGCLLSSSPDGPTKGFFFVPSEKVPKARLSATFGFNPCVNTGCGKPAVRPLVDTGAMVFVVFGIIGVNRTRQVDNHVIGDPGSVVYDSSFDLFKEIGHLCHLCKAIAANSELVKPGGAQCLPSGYSISSFLQMLHPECKELPEPNLLPGQLSHGAVGVREGRVQWISMAFESTTYKGKSSFQTYSDYLRWESFLQQQLQALPEGSVLRRGFQTCEHWKQIFMEIVGVQSALCGLVLSLLICVAAVAVFTTHILLLLPVLLSILGIVCLVVTIMYWSGWEMGAVEAISLSILVGSSVDYCVHLVEGYLLAGENLPPHQAEDARTQRQWRTLEAVRHVGVAIVSSALTTVIATVPLFFCIIAPFAKFGKIVALNTGVSILYTLTVSTALLGIMAPSSFTRTRTSFLKALGAVLLAGALGLGACLVLLQSGYKIPLPAGASL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*************** * .*: . ** :.** * ***:*.*.****: ****************************.***********************************:****************************************:** ****** * *** *:* .::* * ***:*. *. .:*** *************:*****************************************************************************************************************************.**************************************************************************************************************************************************************************:****************************************:*******.************:********.****:*.**:*******:*:***:.* .*****:**********:**:**.************ *****:.: .***:*:.*******:****:************.***************************************************************:*******:*****.****.*:* *: .*********:***************************************:*************************:*:*****:***********************************:*:*******************:***::*****:*************************************:***:*:***********:***************:******.**************************************************:***********************************:****::****.*:****************:****** *******************:***************************************************************: ::*. :**********************************************************************.*************************:*****:********:**:*", "identical_positions": 1224, "similar_positions": 93, "identity": "87.93%" }, { "cls_id": "homologset.agr.MGI:2444412", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CCJ9-6", "uniprot_id": "P20L1_MOUSE", "id": "Q8CCJ9-6", "name": "PHD finger protein 20-like protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKKPPNRPG-ITFEIGARLEALDYLQKWYPSRIEKIDYEEGKMLVHFERWSHRYDEWIYWDSNRLRPLERPALRKEGLKDE-------------------------------EELFDFKAGEEVLARWTDCRYYPAKIEAINKEGTFTVQFYDGVIRCLKRMHIKAMPEDAKGQVKSQHPLSWCCPIDPAGSCNQSMGSEDWIALVKAAAAAAAKNKTGTKPRASANSNKEKERDGGKWFKLPSKKAETSTCIVTAEIEKKEELPTSSETFG-LHIDTVP-KIVFPQPESTLTNKRKNNQGNSFQAKRARLNKITGLLASKAVGVDGAERKEDCSATAPVLEQAISPKPQSQKKNEAVIS--SSANTQKPALLSSTLSSGKARSKKCKHESGESSGCIK-------TPKSPLAPELIQAKDLTLVSQLSS-VINKTS-----SPQPVNPPRPCKHSERRR--------------RSQRLATLPMPDDSLEKLSSSSSATDGKAFSISSQNQQQSSVP--------EVPAIAYVPLQKLGPCLPLDLSCGSE-VTGSRTPHPSYHGGECPRE---------------------------------EKEETPLFANP-------------TSKVVSDV------KGAAAATGIS--------------------------------------------------------------KTEKKVKLEEKTSTAFGKRKEKDKEKKEKRDKDHYKPKQKKKKKKKKKSKQHDYSDYEDSSLDFLERCSSPLTRSSGSSLAPRSTFTEKTTTYQYPRAILSVDLSGENLSDVEFLDDSSTESLLLSGDEYNQDFDSTNFEESQDEDD-ALNEIVRCICELDEENGFMIQCEECLCWQHSVCMGLLEDS-IPEQYICYICRDPPGQRWSAKYRYDKEWLNNGRMYGLSFLKEN-YSHLNAKKIVSTHHLLADVYGVTEVLHGLQLKIGILKNKHHPDLHLWAYSGKRKDQDQAVAEAERKITPQDRANSEGKECVQNHKEPA---LRMEETYITSEHSYQKPQSFSQDCQSLTDPGSSDDDDASSFEEDGELRVPDKSHLLY--KNRGVSEKNPASGNKVFVYNDKKGTEGPGDSHLQWQLNLLTHIENVQNEVTSRMDLIEKEVDVLESWLDFTGELEPPDPLARLPQLKRHLKQLLLDVGKVQQIATLCSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4V9H5-1", "uniprot_id": "P20L1_RAT", "id": "Q4V9H5-1", "name": "PHD finger protein 20-like protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKKPPNRPG-ITFEIGARLEALDYLQKWYPSRIEKIDYEEGKMLVHFERWSHRYDEWIYWDSNRLRPLERPSLRKEGLKDE-------------------------------EDLFDFKAGEEVLARWTDCRYYPAKIEAINKEGTFTVQFYDGVIRCLKRMHIKAMPEDAKGQVKSQHPLSWCCPIDPAGSCNQSMGSEDWIALVKAAAAAAAKNKTGSKPRTSANSNKEKERDGGKWFKVPSKKAETSTCIVTAEIEKKEELPTSSEPFG-LHIDSVP-KIVFPQPESTLTNKRKNNQGNSFQAKRARLNKITGLLASKAVGVDGAEKKEDCSATAPVLEQAISPKPQSQKKNEAVIS--SSANTQKPALLSSTLSSGKARSKKCKHESGESSGCIK-------APKSPLAPELIQAKDLTLVSQLSS-VINKTS-----SPQPVNPPRPCKHSERRR--------------RSQRLATLPMPDDSLEKLSSSSSATDGKVFSISSQNQQESSVP--------EVPAIAYVPLQKLGPCLPLDLSCGSE-VTGSQAPDSSYPGGECPRE---------------------------------EKEETPLFANP-------------TSKVVSDV------KGAAAATGIL--------------------------------------------------------------KTEKKVKLEEKTSTAFGKRKEKDKERKEKRDKDHYKPKQKKKKKKKKKSKQHDYSDYEDSSLDFLERCSSPLTRSSGSSLAPRSTFTEKTTTYQYPRAILSVDLSGENLSDVEFLDDSSTESLLLSGDEYNQDFDSTNFEESQDEDD-ALNEIVRCICELDEENGFMIQCEECLCWQHSVCMGLLEDS-IPEQYICYICRDPPGQRWNAKYRYDKEWLNNGRMYGLSFVKEN-YSHLNAKKIVSTHHLLADVYGITEVLHGLQLKIGILKNKHHPDLRLWAYSGKRKDQDQVVAGAERKVILQDTANSEGRKYVQNHKEPP---LKMEETYITSEHSYQKPQSFSQDCHSLTDPGSSDDDDVSSFEEDGELHVADNSHLLYSVKERGVSEKNPASENKVFVYNDKKGMEGPGDAHLQWQLNLLTHIENVQNEVTSRMDLIEKEVDVLESWLDFTGELEPPDPLARLPQLKRHIKQLLLDMGKVQQIATLCSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A8MW92-1", "uniprot_id": "P20L1_HUMAN", "id": "A8MW92-1", "name": "PHD finger protein 20-like protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKKPPNRPG-ITFEIGARLEALDYLQKWYPSRIEKIDYEEGKMLVHFERWSHRYDEWIYWDSNRLRPLERPALRKEGLKDE-------------------------------EDFFDFKAGEEVLARWTDCRYYPAKIEAINKEGTFTVQFYDGVIRCLKRMHIKAMPEDAKGQVKSQHPLSWCCPIDPAGSCNQSMGSEDWIALVKAAAAAAAKNKTGSKPRTSANSNKDKDKDERKWFKVPSKKEETSTCIATPDVEKKEDLPTSSETFG-LHVENVP-KMVFPQPESTLSNKRKNNQGNSFQAKRARLNKITGLLASKAVGVDGAEKKEDYNETAPMLEQAISPKPQSQKKNEADIS--SSANTQKPALLSSTLSSGKARSKKCKHESGDSSGCIK-------PPKSPLSPELIQVEDLTLVSQLSSSVINKTS-----PPQPVNPPRPFKHSERRR--------------RSQRLATLPMPDDSVEKVSSPSPATDGKVFSISSQNQQESSVP--------EVPDVAHLPLEKLGPCLPLDLSRGSE-VTAPVASDSSYRN-ECPRA---------------------------------EKEDTQMLPNP-------------SSKAIADG------RGAPAAAGIS--------------------------------------------------------------KTEKKVKLEDKSSTAFGKRKEKDKERREKRDKDHYRPKQKKKKKKKKKSKQHDYSDYEDSSLEFLERCSSPLTRSSGSSLASRSMFTEKTTTYQYPRAILSVDLSGENLSDVDFLDDSSTESLLLSGDEYNQDFDSTNFEESQDEDD-ALNEIVRCICEMDEENGFMIQCEECLCWQHSVCMGLLEES-IPEQYICYICRDPPGQRWSAKYRYDKEWLNNGRMCGLSFFKEN-YSHLNAKKIVSTHHLLADVYGVTEVLHGLQLKIGILKNKHHPDLHLWACSGKRKDQDQIIAGVEKKIA-QDTVNREEKKYVQNHKEPPRLPLKMEGTYITSEHSYQKPQSFGQDCKSLADPGSSDDDDVSSLEEEQEFHMRSKNSLQYSAKEHGMPEKNPAEGNTVFVYNDKKGTEDPGDSHLQWQLNLLTHIENVQNEVTSRMDLIEKEVDVLESWLDFTGELEPPDPLARLPQLKRHIKQLLIDMGKVQQIATLCSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PN27-1", "uniprot_id": "A0A8M9PN27_DANRE", "id": "A0A8M9PN27-1", "name": "PHD finger protein 20-like protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKKTPNRPG-ITFEVGARVEAQDYLQKWYPSRIEKIDYDEGKMLVHFDRWSHRYDEWILWDSNRLRPLERPALRKEGLKEEEVSERLSEMRASRLRELPGSTESTEDQKDLPQQRQELRDGEEVLARWTDCRYYPAKIESINKEGTYTVQFYDGVIRCVKRIHIKSMPEDAK-------------------------GQQDWIALVKAAS-AAAKNKGGNRPRTSANSNKDREDRREQRSDEEEDDDDADEDDDDDEDDDEEEEDSESEKLADLDSEEEDSKPPAEELESAIAKRRSKRQGNPCSIKRSRLGKGAG-------CADTETELKAETKELPVTPQQKVPSPEPSPADEKSQS--VSAQKTTPSLSNP--PACKARSRRLKHDSGESASSCQNT--PAAPESSPLPSPTQTLPDSTHTAPSSSPQRRRRSQRLATTSDLICPPSPHTRDTATHPTPPPDGPLIADEDSSTLVKTEAISQKPVSESPSTATSTASAQAPITEKEKMNDVLPSNQAALEGNSPAVVPAAIQKVPSRTPKANKHAREPIINTKRSDDPLAPNECIIDLDHNKFKCKVSGCSKAFRKAKLLDYHLKYYHNTEKEMDTEVCSPEREGRTRATSASMPTSTLSDVPDNKRRRTVSTSSSLSSQGFMLQMDSGGCVRPSKFCKKKRSSASMSSDSTEVSLPPPTFDNLHDKIIKKDKHLDGLCIKTERKFKLDDKCQLFVKKR---DKDRRDRKEKDLFRIKQKKKKKKKKKSKLHCYPDLDEMSLAYLERPSSPPHRSSSS--------AFKHSTFQYPRAILSVDLTGENLSDIDFLEDSTTESLLFSGDEYNQDLDSITMEDFQDEDDDGADEIVRCICEMDEENGFMIQCEECMCWQHSVCMGLLEDS-IPEQYICYICRDPPGQRWSAKYRHDKDWLQKGHMYGLSFLTEN-YSHQNAKKIVSTHQLLADVYSVKNLLHGLQLKMDILQNKHNPSLHLWARSWVNSDEDQPMGGVPDGLHFKEHLNQNSN----------------PETYITSEHSYQKP------------PGTG----AEHTRDEQGMQMGS----QFNIKEEEVSSAIALSG----CVND--SSVEQTRNCLQWQMNLLTHIEDIQNQLSGRMDLIEKELDVLESWLDFTGELEPPDPLARLPQLKCRIKQLLTDLGKVQQMSTLCSV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGA4-1", "uniprot_id": "MBDR2_DROME", "id": "Q9VGA4-1", "name": "Protein MBD-R2", "aln": "MGRRCCVANCPSTSRLLEHNGVTYHSFPLDPIIRAIWIKNSRISLERQITKSVLVCSRHFRRLDFNTIRNGKYLLKPRVFPTVFPWGKMDTAEIEADQRALQHASVEGTTETPGNAQSSTNDDVIKATVDQIVAQILSESAERKATEEGKTGKAADDVKNTPESGEDANKAAAKEPSGTPVAASSEATVPAPGSASSSNSPLPGTPPKYSNPHNLTIGARLEALSVEGNWLPARIVEVNETEQTLLVRFERN----HKLKVSPSTSGSFQEWMAIKSERLRQRLSN----------------------------RVLPVFELDEKCMARWSGPRKFPGTIRKLLGNDTYEVLFDDGYVKNVRAVHMNKMPKQLPPVQVAEEG----ASKSPTPVGTPVSSAPVAPKRASTGSLGGSSGSSGSKKSKCAPQRRDWPLLDMASLDIASLGLPEIPHDGEWTCHWVNDQPIGTEGFLIVGEHQKPTVIVQDWRLPPGWIKHMYQRSNVLGKWDVILVSPSGKRFRSKSDLKLFLESQNLVYNPDVYDFSIHRRRAKDINAYVYTHGYNPQPPPKPRPMDVSMNSTLDQSITSQHSLPSTPMPVKESQYMEAPVASLMPPAELMSPQTQPADETKPKIEAEILEASEGGTSQLMLADPHVVENGFAFIG-----------GLKVKIQDNLYVCPREDCAKTYRKEDFLLIHIRHYHKEFAEHVS-------HCPKMQELAVKRTHPSSIDQVEAVPKNQIPNQQFFAKMHQQDLQQS---------------------------RSFKRQSVSATATSSTP---------SDITPTKALLSPKMEPPSVSPTVESGIKQED---------------------------------------------------------VSLDAGPTQSFNPSLSRSCKRARLSPSKRPSGSRKSNRQRSQRRPILSDNPAGHGLTEQDVEETRQSFNTPTPDTRIDSKKRRSGAATTPISSIDSPAMGDSVSTPSSNDQTDINAALAPPPAETLSKAPQYIKENGELIRIVRMRQEE-----IINCICEYGEEDGLMIQCELCLCWQHGACNGIVKEADVPDKYVCYICRNPQRGRDSMRFKHDQDWLFEGKLPVAAYHTANPQATKQFELLKRSHTLTGNLLDAKRSMHSLLVKINIARNRCHPKLYLWAKKWDEDNLDSTALTPVKRAKLEAPDLPNVPQ---------------PEAAIDPEE------------------------------------------CQYRLIEHIKVQQS---------------------LVLDRLNDIEAEMDELEKEDTLDDLKDADISTTKEALATFIKELETMKRLAKLNQVAN-MKQTLRDSATSK--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08923-1", "uniprot_id": "CTI6_YEAST", "id": "Q08923-1", "name": "Histone deacetylase complex subunit CTI6", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESTAIVPKGPVVGSEDMEKAEVIASGS--------------TDIISTTSTATTTAAIGSVQEESVKQE--------------------------------DVPMEGGEGEVEEEEGETRCICGELDTPDDSG-----FFIQCEQCSSWQHGYCVSITQDN-----------------------APDKYWCEQCRPELHQLFTTDTGEARSIYKPVQEKRRQSRRK----ARSAAASKSHAANEAEKSPRNTSNTDDNVDDIGDEEDE-------VEDEASAVALAKDGNTRSSRRRRRN-----------------SMDDASTDQYSLDPGDSDKKLLDRKRATFMAR---EEKQYQRMLEKALKESRRTSHQEDPESYEN--------------------------------------------------------------------------------DADIYQGDTDNHNGTTRLQTDVMLTEGKPDSVTNDDMKESLRP---------SKEQSMEKTNDVEKEASQEKESSTGSAQDTEKTDEPILPLTSISS---------------------------------SEDDSRK-ASS---------------------------------------------------------------------------------------------------RGSKRVSKPARKGNRTRRSNTSSDTNQNRRSADIGTDKPVKPRLPPQRTSLNEMRRRVSAILEFISRTQWELSEDQSDR-------EEFVRFVENQHFVEKVDTIYNGYNESLSMMDDLTRELLLWEKKYSNNTNAIQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . : : . . *. :::.* :::. : . * . : .. * : * :. . . . * ... . .: : . : . . .* . . . * . . .. . : . : . . . .. . : . .: . . : : ... : . . ... . :. .: . . * :* :: . ", "identical_positions": 11, "similar_positions": 85, "identity": "0.78%" }, { "cls_id": "homologset.agr.MGI:2444413", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M3B8G6-1", "uniprot_id": "A0A8M3B8G6_DANRE", "id": "A0A8M3B8G6-1", "name": "", "aln": "-----------------------------------------------------------------MDAGGCEATER-------------------QFPGLSKKRRPAGRHNTALKEEEEEDSVYSG--GDRSRKDTARSRSTALLTR-------VDKNAIMCDLKSASSSSSM--------------------IFTRFSGRNFSGNGKRKFAVRTWSWWAFFCLQVHVLEAVTQGDVAPYFKTEPGPPEIHLEGNRLVMTCLAEGSWPLEFKWMLNNTDITAFSPEYKYTISSLQRSNMGVYQCVVRNRMGALLQKKAEIQVAYMGDFIDNDQ-RKTVTQGRAAILNSPAVSCFPRPQVTWFRDGYKIIPSNRIAITLENQLVVLATAASDAGRYYVQAVNEKNGENKTSPSIYLNVAANKKYRG-SHDSEAPADPVAPVIVIPPRNTTVVAGISEATLECVANARPVEKLSLVWRRNGVEVASG------VGSFSRRLTIINPTSTDVGMYVCEALLLDSSVKPAEARAFLSITEAPYFTAEPRRKMMGEVEKSVDIQCQARGVPMPKLEWYKDAVPLSKLNNPRYKIISS-MGLQVRKLQPSDAGIFQCFARNSAGEAQVHTYLDVTSMAPAFTAPPLDITVTDGAVAAFTCRVSGAPKPAIVWRRDTQILASGSVQIPRFTLLESGGLQIQPVVLQDTGNYTCYAANSEGAINASASLTVWSRTSISSPPTDRRVIKGTTAILECGATHDPRVGVRYVWKK-DEELVSHSRGGRISLQ-EGSLHISQTWSGDIGNYTCDVISEAGNESKEARLEVIELPHSPRNLQAS-LNANDSRSVDLSWMRPFDGNSPLLHYVVELSEN-------------NSPWRVYLSDVDPSGTGAMVKGLTPARSYQFRVCAVNQVGRGQYSTETNRLMLREEPPSAPPKNIVASGRTNQSIMVQWQPPPEPQLNGVLRGYVLRYRLAGLP-GEYQQKNISSPEINYCLITELIIWTQYEIQVAAYTGAGLGVFSQPVTEYTLQGVPTAPPQGVEAKAVNSTTIEFSWNPPPQQFINGINQGYKLMAWPERSPE--------EVIVVTITPDYHGTRHLGYISGLRKFSWYLTSVLCFTTPGNGPRSAPKLVQTFEDIPGPVGRLSFTEILDTSLKVSWEEPVDKNGIITGYLVSWEVQGNNQSRVARNLANTTLDYKVTGLTSLTTYTLEVAAMTEAGVGTVTSSTISSGVPPELPGPPSNLVISKISSRSATLKFRAGDDGKTAISKWIVEGQVGSIGEDE---EWKVLYEKENDPEAQMLEVPNLTPFTHYRFRMRQVNIVGPSAVSVPSRVIQTLQAPPDVAPSSVTVRTASETSLWLRWVPLPESEYNGNPESVGYRVRVMRADL---RGEASTRLLNDRLEREITLEGLEEWTEYQLQIQAFNSIGPGPWSESVKGRTRESVPSGAPENVTAEAMSSSRILVTWGPVPEHEQNGNILGYKVLFKEKDSDSEAQVNVVKGNLTQSVLLRNLRKYVQYEIQVLAFTRIGDGQLSNPPVLERTKDDVPGPPMRLVFPEVRLTEVRVVWQPPVDPNGIIMGYQVAYRLDSGDPNQFITIEVGPDTRQFTASSLTPESAYIFRISAKTEQGWGSPAQAVVITTEIRERPQPPRQLRVPQDHVQSRKLLLNWVPGGDGSSPVRYFTLQTQELPSGEWIPHSSAISHNYSSWEVDRLKPFTSYKLRMMATNDVGDSKYSQETDAITTLQDVPDEAPMIQSVKPSTTTSVLVQWQTPKEESVN--GVLVGYRLYYRELQYDS-TPQDSKRPVNSSQLRTELTAKSTVKTVSNPS-LTEFELTQLQKYRRYEIVMTAYNVIGESPPSAPVEVFVGEAAPSVAPQNIQINTLSSTQLEVQWEPPPAETQNGIIQGYKILYWEMDS-------QNETERVKILFRPETNMRLKNLTSYTYYMVKLLAFNAAGDGPFSEPRRGRTLQAAPSAPSFISFSEVTSSTLNVSWGFPLSPNGVVEGYRVVYEPTAPIQGVTKVVTVDIRGSWQRWLKVRDLTKGMTYCFRVQAKT-IAYGPEAEANITAGPVKGSPGSPVEMSITKTGSMLNIQWTAGETGAGHVTGYVIEARPSDEGLWDTFVRHLPPTSTSHSVSLDRLRQGISYQFRVLAVNEFGYGE----------PSAPSAAMSAQVDTPFYEEWWFLIVLALCGLILLLLVVFGLVLHGQNRKYKSCGTGKAVSTVEETVTLDN-------------GGFTALELNSRPVHVKGVFLRKNGTR---------SPPRPNPAGLRYSDEDICSNYNGVVSTESTALTERPAEMSESEATDSECEEEPIK---HSFVNHYMSDPSYFNSWKRQQKGLKQTLACSYEECASGDNES-YYQTVVTQHSVGGVYTPAGQPAPGSRTPVTGFSSFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YY19-1", "uniprot_id": "A0A8M6YY19_DANRE", "id": "A0A8M6YY19-1", "name": "", "aln": "------------------------------------------------------------MSRLGTQKSGSRAADGGLRSVLVILEWCTPETWSFWFEGIVSFSTKCVDECEGLQKAVRHESKAAGKVADSVLNSPACGMNENRLVN-------AVKQSAHFPLSSLTSTSAASKDFSFNGGQSTLTKGKVKGIINRQGNTAKAMTGKARCGMWAWIFALVFLWNTHMLRAQ---DTAPYFKTEAGGAQTHLEGNRLVLTCLAEGSWPLEFKWMRNSTDITEYTPEYRYTIVSLKREDAGVYQCAVRNRMGALIQTRADVRVAYMDNFAELEQ-RKTVSQGRAAVLNPPAVTSFPRPQVTWFRDGVKIIPNHRVAITLDNQLVVLSTAMADAGRYYVQAVNERNGENKTSPSIYLSIAINKRNRGSLADVIAPAELVAPVIVIAPKNTSVVVGASEATLECVANARSLDRLQVFWKRNGVRLTAG------VDSFGRRLVISNPTSADGGLYVCEATLRNSSQKSTEAKAYLSVLESPHFTSKPKRYMIVEVEKNVELQCHAKGVPTPKLEWFKDAIPLSTLNNSRYKLTTSSMVLQVRRIQPDDAGIFQCFAENTAGEIQAHTNLVITSMSPLFTTPPSDITVTDGTSAVFTCDTSGAPKPAIVWRKGSQVLASGSVQTPRFTLLESGGLQILPIMPSDAGNYTCLASNTEGLVNATVALTVLSRTFISTPPEDQRVIKGTTAVLHCAATHDPRVTVRYSWKK-GTKPLSVSTGGRVSMK-EGSLQISQTWSGDIGDYTCRVISPAGNDSKSARLEVIELPHSPRNLQVA-LNETDSRTVLLSWVRPFDGNSPLLHYIIEFSEN-------------NSPWKVYMDDVSPTLASLLVIGLTPARTYQFRVCAVNQVGRGQYSAETNRLMLREEPPSAPPKNIVASGRTNQSIMVQWQPPPEPQLNGVLRGYVLRYRLAGLP-GEFQLKNITSAEINYCLIGELIIWTQYEIQVAAYTGAGLGVYSQSATEYTLQGVPTAPPQDVEAVALNSTTIKFTWTPPPQQFINGINQGYKLLVWPEHCPD--------CITMVTIAPEFHGSRHYGYVSNLRKFTWYETAVLCFTTPGDGPASTSQLIQTHVDKPGPVTQLSFTEILDTSLRISWQEPEDKNGIITGYVLSWQEAGQNETLVSQTLSNSTLAYKVTGLTSLTTYALQVAAVTQAGVGASTSSTISTGLPPELPGAPSNLVISNISPRSVTIQFSPGSDGKTEISKWIVEGQVVTVGEEEKEAEWKVLYERDSPPASDTLEIPNLIPFTQYRFRMKQVNIVGSSPFSESSRLMQTLQSSPDVAPTELVVFSASETSLRIRWEPLPEAAYNGNPESVGYRVRAQRADG---FGQPRMETVSDRLSCEVTVEGLEEWTDYELSIQAFNSIGPGPWSSHVLGKTKESVPSGAPENVSAEAMSSTSVLVTWGSVPEHQKNGHILGYKVLYREKDSDRAPQAHLVNGNQTHMLLLRNLSKFTVYEIQVLAFTRVGDGPPSLPPTAERTKDDVPGPPVRLMFPEVRLSSVRVVWQPPSEPNGIIMGYQISYRLDINDPNKFTTVEVGSNARQFTVTGLMPESAYVFQITARTLQGWGPADEAIVITTEKRERPQAPRRLTVPQKGVESYKLRLHWMAGGDGSSPVRYFTLQTLELPDGDWKTHTSSIPHNNSSWEVDRLKPYTSYKFRMMATNDVGDSAFSKETEPVTTLQDVPGEAPVILLVKPSTTTSVIVQWQPPAEGTVN--GILVGYRVYYRELPSES-NPK-VVQSTNQSTISLEFRAKSTFKTVSSPS-LTEFELTQLSKYRRYAIVMTAFNVVGESPSSAPVEVFVGEAAPSVAPQNIQVKSVSSNQLDVEWQPPPVETQNGNIQGYKIHYWEKDR-------QNETEKELVLFVPETCVHLKNLTSYTSYLVQLSAFNAAGDGPLSTARKGRTLQAAPGSPSRVVFSEVTGSSLNVSWGAPLQPNGVLEGYRVMYEPTAPVHGVSKTVTVDIKGNWQRWLKVRDLMRGVVYRFKVQART-ISYGPELEANITAGPVEGSPGSPLQTSVTKSASALTLHWTKGSEGAGPVTGYVIEARPSDEGLWDTFVKHLPAGSLSYTISLDRLRSGVAYEFRVISVNRFGYGD----------PSPPSTAMSALSETPFYEEWWFLIVMALISLILILMVVFGLLLLGQNKKYRSCGTGKHISTVEESVTLDN-------------GGFTALELNSRHLNVKSSFLKKNGTR---------SPPRPSPGGLHYSDEDICNNYNGAVLTESTTLTEKPTELSESEVSDSDYEDEQPK---HSFVNHYMSDPTYYNSWKRQPKGVKT--GGGYEECAMTDAEGGYYQTVVTQHSVGGVYTPTGQPTAGTRTPVTGFSSFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I6A427-1", "uniprot_id": "A0A8I6A427_RAT", "id": "A0A8I6A427-1", "name": "", "aln": "MGRGGRGGRGESRRAGGRTFSSAPGGGGGGRGGGRGVLLSSPQRALRGRRCTAARSGDDVPSISPLADNFSSARLAVHRSPDAAPRSSPLPQRVCALPPPCPSRGARGWRLRGMAR-ARPSVAGGGG--AAPPERAGPGRPRRSRTG-------HHCDPERPGLRAAPRTPG-------------------------PGAG----RRSAKLRPGR-GWWALLLLQLHLLRALAQDDVAPYFKTEPGLPQIHLEGNRLVLTCLAEGSWPLEFKWIRNDSELTAYSSEYRYIIPSLQKLDAGFYRCVVRNRMGALLQRKSEIQVAYMGNFMDADQ-RKTVSQGHAALLNLLPITSCPRPQVTWFREGHKIIPSSRIAITLENQLVILATTASDAGAYYVQAVNERNGENKTSPFIHLSVARD----------TGTQEAMAPVIVVAPGNRSVVAGSSETTLECIANARPVEELSVHWKRNGVRLTSG------LHSYGRRLTIINPTSADTGMYVCEATLRGSAFEPARAKAFLSIIEPPYFTAEPESRILGEVEETVDIPCRAMGVPLPTLQWYKDAVPLSKLQNPRYRVLPS-GGLHIQKLSPEDSGIFQCFANNEGGEIQTHTYLDVTNIAPAFTQRPVDTTVTDGMTAVLRCEVSGAPKPAITWKKGNHILASGSVRIPRFMLLESGGLRIAPVFIQDAGNYACYATNTEASVNASAMLTVWNRTSIVHPPEDRVVIKGTTATLCCGATHDPRTSLRYVWKK-DNAVITPSSSSRIVVEKDGSLVISQTWSGDIGDYTCEIVSEGGNDSRTARLEVIELPHPPQNLLAS-LSSARSHSVTLSWVRPFDGNSPVLYYIVQVSEN-------------NSPWKVHLSNVGPEMAGVTVSGLTPARTYQFRVCAVNQVGKGQYSTETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLP-GEHQQRNISSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQAEAVNSTTVHFLWNPPPQQFINGINQGYKLLAWPADAPE--------TVTAVTIAPDFHG-THHGYITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTHEDRPGAVGHLSFTEILDTSLKVSWQEPLERNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAMTTAGVGLTTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTAICRWIVEGQVGAIGDEE---EWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPFSQSSRVIQTLQAPPDVAPTSLTVRTASETSLRLRWVPLPDSQYNGNPESVGYRVKYWRSDQ---PSSALAQVVNDRLERELTIEELEEWTEYELRMQAFNAIGAGPWSELVRGRTRESVPSASPENVSAEAVSSTQILLTWASVPEQDQNGLILGYKVLYRAKDLDPEPRSHVVRGNHTQSALLAGLRKFVVYELQVLAFTRIGNGVPSSPLILERTKDDTPGPPVRLVFPEVRLTAVRIVWQPPEEPNGVILGYQIAYRLASGSPHTFTTVEVGATVRQFTATELAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTVQVRELPGGEWQTYSSSISHEATLCAVERLRPFTSYKLRLKATNDIGDSDFSAETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLN--GLLQGYRIYYRELESETGLSPEPKTLKSPSALRAELTAQSSFKTVNSSSTLTTYELTHLKKYRRYEVIMTAYNIIGESPASVPVEVFVGEAAPAMAPQNIQVTPLTASQLEVTWDPPPPESQNGNIQGYKVYYWEADS-------RNETEKMKVLFLPEPVVKIKDLTSHTKYLVSISAFNAAGDGPRSDPCQGRTHQAAPGPPSFLEFSEITSTTLNVSWGEPSAANGILQGYRVVYEPLAPVQGVSKVVTVDVKGNWQRWLKVRDLTKGVTYFFRVQART-IAYGPELQANVTAGPAEGSPGSPRNVLVTKSASELTLQWTEGNTGNTPTTGYVIEARPSDEGLWDMFAKDIPRSATSYTVGLDKLRQGVTYEFRVVAVNKAGFGE----------PSRPSIAVSAQAEAPFYEEWWFLLVIALSSLLLVLLVVFVLVLHGQSKKYKNCGSGKGISNMEETVTLDN-------------GGFAALELNSRHLNVKSTFSKKNGTR---------SPPRPSPGGLHYSDEDICNKYNGAVLTESVNLKEKSVDGSESEASDSDYEEALPK---HSFVNHYMSDPTYYNSWKR--RPP--AAAPHRYEAVAGAEAGPHLHTVITTQSAGGVYTPAG---PGARAPLTGFSSFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UH53-1", "uniprot_id": "SDK1_MOUSE", "id": "Q3UH53-1", "name": "Protein sidekick-1", "aln": "-----------------------------------------------------------------------------------------------------------------MAR-ARPSVAGGGV--AAPPERAGPGRPRRSRTG-------HHCDPECPGLRAAPRTPG-------------------------PGAG----RRAAKLRPGR-GWWALLLLQLHLLRALAQDDVAPYFKTEPGLPQIHLEGNRLVLTCLAEGSWPLEFKWIRNDSELTTYSSEYKYIIPSLQKLDAGFYRCVVRNRMGALLQRKSEIQVAYMGNFMDTDQ-RKTVSQGHAALLNLLPIVSCPQPQVTWFREGHKIIPSSRIAITLENQLVILATTASDAGAYYVQAVNEKNGENKTSPFIHLSVARD----------TGTHEAMAPIIVVAPGNRSVVAGSSETTLECIANARPVEELSVHWKRNGVRLTSG------LHSYGRRLTITNPTSADTGMYVCEATLRGSTFEPARARAFLSIIEPPYFTAEPESRILGEVEETMDIPCRAMGVPLPTLQWYKDAVPLSKLQNPRYKVLPS-GGLHIQKLSPEDSGIFQCFASNEGGEVQTHTYLDVTNIAPAFTQRPVDTTVTDGMTAVLRCEVSGAPKPAITWKRGNHILASGSVRIPRFMLLESGGLRIAPVFIQDAGNYTCYAANTEASVNASAMLTVWNRTSIVHPPEDRVVIKGTTATLCCGATHDPRTSLRYVWKK-DNVVITASSSSRIVVEKDGSLVISQTWSGDIGDYTCEIISEGGSDSRTARLEVIELPHPPQNLLAS-LSPARSHSVTLSWVRPFDGNSPVLYYIVQVSEN-------------NSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNQVGKGQYSTETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLP-GEHQQRNISSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQAEAVNSTTVHFLWNPPPQQFINGINQGYKLLAWPADAPE--------TVTVVTIAPDFHG-IHHGYITNLKKFTAYFTSVLCFTTPGDGPPSSPQLVWTHEDKPGAVGHLSFTEILDTSLKVSWQEPLERNGIIMGYQISWEVYGRNDSRLTHTLNSTMHEYKIQGLSSLTTYTIDVAALTAAGVGVTTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTAICRWIVEGQVGAIGDEE---EWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMRQVNIVGPSPFSQSSRVIQTLQAPPDVAPTSLTVRTASETSLRLRWVPLPDSQYNGNPESVGYRVKYWRSDQ---PSSALAQVVSDRLERELTIEELEEWTEYELRMQAFNAIGAGPWSELVRGRTRESVPSAAPENVSAEAVSSTQILLTWASVPEQDQNGLILGYKVLYCAKDLDPEPRSHVVRGNHTQSALLAGLRKFVVYELQVLAFTRIGNGVPSSPLILERTKDDTPGPPVRLVFPEVRLTAVRIVWQPPEEPNGVILGYQIAYRLASGSPHTFTTVEVGATVRQFTATELAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTVQVRELPGGEWQTYSSSISHEATACAVERLRPFTSYKLRLKATNDIGDSDFSAETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLN--GLLQGYRIYYRELESETGMSPEPKTLKSPSALRAELTAQSSFKTVNSSSSLTTYELTHLKKYRRYEVIMTAYNIIGESPASVPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKVYYWEADS-------RNETEKMKVLFLPEPVVKIKDLTSHTKYLISISAFNAAGDGPKSDPCQGRTHQAAPGPPSFLAFSEITSTTLNVSWGEPSAANGILQGYRVVYEPLAPVQGVSKVVTVDVKGNWQRWLKVRDLTKGVTYFFRVQART-IAYGPELQANVTAGPAEGSPGSPRNVLVTKSASELTLQWTEGNAGTTPTTGYVIEARPSDEGLWDMFAKDIPRSATSYTVDLDKLRQGVTYEFRVVAVNKAGFGE----------PSRPSIAVSAQAEAPFYEEWWFLLVMALSSLLLILLVVFVLVLHGQSKKYKSCSTGKGISNMEETVTLDN-------------GGFAALELNSRHLNVKSTFSKKNGTR---------SPPRPSPGGLHYSDEDICNKYNGAVLTESVNLKEKSVDGSESEASDSDYEEALPK---HSFVNHYMSDPTYYNSWKR--RPP--AAAPHRYEAVAGAEAGPHLHTVITTQSAGGVYTPAG---PGARAPLTGFSSFV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z5N4-1", "uniprot_id": "SDK1_HUMAN", "id": "Q7Z5N4-1", "name": "Protein sidekick-1", "aln": "-----------------------------------------------------------------------------------------------------------------MARGARPSAAGGGGGGAEPPERAGPGRPRGSPPGRARPSLAPRPGPEPSRPRAAPETSGG----------------------DTAGAGRCGGRRAAKLGPGRRGWWALLALQLHLLRALAQDDVAPYFKTEPGLPQIHLEGNRLVLTCLAEGSWPLEFKWMRDDSELTTYSSEYKYIIPSLQKLDAGFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQ-RKTVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARD----------VGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRITSG------LHSFGRRLTISNPTSADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLAS-GGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKK-DNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVS-PNSSHSHAVVLSWVRPFDGNSPILYYIVELSEN-------------NSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLP-GEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPE--------AVTVVTIAPDFHG-VHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEE---EWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDL---QSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLN--GLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADS-------QNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQART-ITYGPELQANITAGPAEGSPGSPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGE----------PSNPSTAVSAQVEAPFYEEWWFLLVMALSSLIVILLVVFALVLHGQNKKYKNCSTGKGISTMEESVTLDN-------------GGFAALELSSRHLNVKSTFSKKNGTR---------SPPRPSPGGLHYSDEDICNKYNGAVLTESVSLKEKSADASESEATDSDYEDALPK---HSFVNHYMSDPTYYNSWKR--RAQGRAPAPHRYEAVAGSEAGAQLHPVITTQSAGGVYTPAG---PGARTPLTGFSSFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O97394-1", "uniprot_id": "SDK_DROME", "id": "O97394-1", "name": "Protein sidekick", "aln": "----------------------------------------------------------------------------------------------------------------------MLKSAASSLRRRRPKTTITATLAIEMPSQ-----------PKLASLLAVLVLLCY-------------------------------------CDSCFFCYADANLQQQNSIVQQQQLQAPRFTTHPSSSGSIVSEGSTKILQCHALGYPQPTYRWLKDGVPVGDFSSSQFYRFHSTRREDAGSYQCIARNDAGSIFSEKSDVVVAYMGIFENTTEGRLTVISGHPAIFDMPPIESIPVPSVMWQSEDGPLNYDIKYAFTHANQLIILSADENDRKGYRAKAINTQLGKEESSAFVHLNVSGD------------PYIEVAPEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKDGLAVETAGVRHTLNDPWNRTLALLQANSSHSGEYTCQVRLRSGGYPAVSASARLQILEPPLFFTPMRAETFGEFGGQVQLTCDVVGEPTPQVKWFRNAESVDAHIESGRYTLNTDNTLVIKKLILDDAAMFQCLAINEAGENSASTWLRVKTSAPIMELPPQNVTALDGKDATISCRAVGSPNPNITWIYNETQLVDISS---RVQILESGDLLISNIRSVDAGLYICVRANEAGSVKGEAYLSVLVRTQIIQPPVDTTVLLGLTATLQCKVSSDPSVPYNIDWYREGQSSTPISNSQRIGVQADGQLEIQAVRASDVGSYACVVTSPGGNETRAARLSVIELPFPPSNVKVERLPEPQQRSINVSWTPGFDGNSPISKFIIQRREVSELEKFVGPVPDPLLNWITELSNVSADQRWILLENLKAATVYQFRVSAVNRVGEGSPSEPSNVVELPQEAPSGPPVGFVGSARSMSEIITQWQPPLEEHRNGQILGYILRYRLFGYNNVPWSYQNITNEAQRNFLIQELITWKDYIVQIAAYNNMGVGVYTEGSKIKTKEGVPEAPPTNVKVEAINSTAARCRWTPPNPQQINGINQGYKIQAWQRRLIDGEWRDIERRMKTVPPSLIDPLAEQTAILGGLEKFTEYNISVLCFTDPGDGVASSQVAVMTMDDVPDEVTGLHFDDVSDRSVKVLWAPPRASNGILTGYTVRYQVKDRPDTLKSFNLTADDTELTVNQLQATTHYWFEIVAWTRVGSGIPKTATIQSGVEPVLPHAPTALALSNIEAFSVVLQFTPGFDGNSSITKWKVEGQTARN------MTWFTICEIN-DPDAETLTVTGLVPFTQYRLRLSASNVVGSSKPSEATKDFQTIQARPKHPPFNVTVRAMSAQQLRVRWIPLQQTEWYGNPRGYNISYKQLVKTPGTIKYVPRSVVIEDHTANSHVLDSLEEWTLYEVKMNACNDVGCSKESDTAVERTREAVPSYGPLDVQANATSSTTVVVQWGEVPRQHRNGQIDGYKVFYAAADRGQQVLHKTIPNNATFTTTLTELKKYVVYHVQVLAYTRLGNGALSTPPIRVQTFEDTPGVPSNVSFPDVSLTMARIIWDVPVDPNGKILAYQVTYTLN-GSAMLNYSREFPPSDRTFRATELLPGKYYSFSCTAQTRLGWGKIATALVYTTNNRERPQAPSVPQISRSQIQAHQITFSWTPGRDGFAPLRYYTVEMREN-EGRWQPLPERVDPSLSSFTAVGLRPYMTYQFRIQATNDLGPSAFSRESVIVRTLPAAPAVGVGGLKVVPITTTSVRVQWSALETALWNGDASTGGYRILYQQLSDFP------------------TALQSTPKTDVHGINENSVVLSDLQQDRNYEIVVLPFNSQGPGPATPPAAVYVGEAVPTGEPRAVDAAPISSTEVRLLWKPPKQSMQNGDILGYKIYYLVTYSPQALEPGRKWEEEIEVVSATATSHSLVFLDKFTEYRIQLLAFNPAGDGPRSAPITVKTLPGVPSAPLHLRFSDITMQSLEVTWDPPKFLNGEILGYLVTYETTEENEKFSKQVKQKVSN---TTLRVQNLEEEVTYTFTVRAQTSVDYGPGISENVTTGPQDGSPVAPRDLILTKTLSSVEMHWINGPSGRGPILGYLIEAKKRDDSRWTKIEQTRKGMMQDFTVSYHILMPSTAYTFRVIAYNRYGISFPVYSKDSILTPSKLHLEYGYLQHKPFYRQTWFMVSLAATSIVIIVMVIAVLCVKSKSYKYKQEAQKTLEESMAMSIDERQELALELYRSRHGVGTGTLNSVGTLRSGTLGTLGRKSTSRPPPGVHLGKSPPRPSPASVAYHSDEESLKCYDENPDDSSVTEKPSEVSSSEASQHSESENESVRSDPHSFVNHYANVNDSLRQSWKKTKPVRNYSSYTDSEPEGSAVMSLNGGQIIVNNMAR------------SRAPLPGFSSFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . : : : : : :.. : . .. . **. :: * * * ::*: :. : ::.. * : * :: : * *:* .** *:::. :::: ****. * : : * ** .*:.*::: .: . * *.* * :. : . : *:* ***::*:: * * .:*:* : *::::*. ::*.:: : . :** *:: * : .* .* . . *:*:*.**.:. *. * ::*: : :. .:.* *.: :..*:. * *.*:. * .. .. * * * : *.* * : . *. ::: * . * * * ::*:::* .:. :. : * :::: .*:.:***:* * .** .. * * :.. :* : * : *. ** * : * . *:*:* *.* *.. * *. :****.* * : *:* * * :* . ::. . *:* ** * ** * *: * ** * * .: ** . . * : . . * *: :: :*.* *. . :.*:*.*:* : * .*.::: ***.*****..* *: . .::: :** ******: :::: * * . :.:*.. : .*..* *****.***.**.*. * :. : * :*.**.** .:*.*.*: ..*:.***** * . ** : **:***** * . :**:. . *: :** *.:* :*:***.. *:**::. . * :*** *** .*:. *:***: . *.** * *********: .* : : *. : : . : .*.**: * :***** **:* *: : * * *. * * * :: * *::: * * ***: ** : :: .. :: : .* .: * : * * :::.* * .* * .::**.:*: * ** .*: *.:*:*.. *..::* .* **:: * :* ****. * .: * : * :: * :..* *:*:**:*: *:**.* * .:: :**:*: *. .* .:.* : * .* :** ** :: : ***.. . : . :.*: . .:: **** *:: ::* * :* . *. . :*:*:*** .* :* *:* **: ::: * **.:.:** * ***::: * . : : .* * * * *:. *.:****:**:*:* * * :* :*.** * .: **:* *: .*::*: * :*** *:.**::* * ... : *. . * * .: * * . * * :*:* *** * * **: **** .* :.: : : .: : * .* ** :*:**:*:: * * * . .. : . : . *:*: :*::*: ****:* * :* *: : ** .* . * **:** :**.. * . ***: *::* . :*: ** . *:.*.: *.* ::: .:* * .*.: *. *:****.*: *: :: .:::.:: : *.** . *** * ***: * :: *. :: . . : * ..* * :.: ***.***** * . :* ..*..* : **::* :*:*:*. * ** : ** * **. . .:* *. .: . *:*::* . :.* * *:*:* : *** . *:*:** .*** :* : :**: * : ::* * * **:***: *:. * : : ..::. . * . :* ***:: *. * . ** . . ***.: **:: :* .::::::*: * : .:. **:. . . ..: :: : * : .:.: . . : :*. :* *****.*..: * .:: . : . :* : . *.. .*: *: : ******* . .. : : . * . ::. : . :*:*:.******", "identical_positions": 598, "similar_positions": 673, "identity": "24.44%" }, { "cls_id": "homologset.agr.MGI:2444415", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY12-1", "uniprot_id": "NB5R2_RAT", "id": "Q6AY12-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "---------------------------------------MSVKKKDLITLQDPEAK--YPLPLIEKEQINHNTRRFRFGLPSPDHVLGLPVGNYVHLLAQINNELVIRAYTPVSSD-DDQGFVDLIIKIYFKNVHPKYPEGGKMTQYLENMKIGDTILFRGPTGRLFYNEPGTLLIKTDKTSEPEKKLVHHLGMIAGGTGITPMLQLIRHITKDT-SDGTRMSLLFANQTEEDILLRKELEEVATTHQNQFSLWYTLDR--------PPSG------WEYSSGFITADMIKEHLPPPGEA-TLILVCGPPPLIQEAAHPSLEQ-------LGYTKDMIFTY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3KNK3-1", "uniprot_id": "NB5R2_MOUSE", "id": "Q3KNK3-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "---------------------------------------MSVKKKDLITLQDPEAK--YPLPLIEKEQISHNTRRFRFGLPSPDHVLGLPVGNYVHLLAQINNELVIRAYTPVSSD-DDQGFVDLIIKIYFKNVHPKYPEGGKMTQYLENMKIGDTILFRGPTGRLFYNEPGTLLIKANKTSEPEKKLVHHLGMIAGGTGITPMLQLIRHITKDT-SDETRMSLLFANQTEEDILLRKELEEVATTHHKQFNLWYTLDR--------PPSD------WKYSSGFVSADMIKEHLPPPGED-TLILVCGPPPLIQAAAHPSLEQ-------LSYTKDMIFIY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6BCY4-1", "uniprot_id": "NB5R2_HUMAN", "id": "Q6BCY4-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "---------------------------------------MNSRRREPITLQDPEAK--YPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKIDNELVVRAYTPVSSD-DDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGPRGRLFYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDP-SDRTRMSLIFANQTEEDILVRKELEEIARTHPDQFNLWYTLDR--------PPIG------WKYSSGFVTADMIKEHLPPPAKS-TLILVCGPPPLIQTAAHPNLEK-------LGYTQDMIFTY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0P487-1", "uniprot_id": "NB5R2_DANRE", "id": "Q0P487-1", "name": "NADH-cytochrome b5 reductase 2", "aln": "MDILTAPVLIGVSIVVITVLY------LFLKPAGSNSTPPKPQNKIPKALQDPSVK--YPLPLIEKEEINHDTKRFRFGLPSSSHVLGLPIGQHIYLSAKVNGSLVVRAYTPVSSD-QDQGYVDLVVKVYYKNTHPSYPDGGKMSQYLDNMKIGDTIDFRGPNGLLVYNGKGKFAIRPDKKSEAEVRKFKHVAMIAGGTGITPMLQLIRSITADS-FDETVCSLIFANQTEKDILLRNELDEVHRNHPSKLKLWYTLDR--------PSEG------WKYSEGFVNAAMMKDHLPPADSD-VLVVMCGPPAMIEKACLPNLLK-------LGYKKENIFAY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JGK6-1", "uniprot_id": "X2JGK6_DROME", "id": "X2JGK6-1", "name": "NADH-cytochrome b5 reductase", "aln": "MARIVESNFVPLAVGVVAVLAGALIVHYLLNKKSTKPRREPNRTARLRTLVDPNDK--YLLPLIEKENLSHDTRRFRFGLPSKQHVLGLPVGQHIHLIATIDNELIIRPYTPISSD-EDVGYVDLVVKVYFKDSHPKFPAGGKMTQHLEQLELGDKISFRGPSGRLQYLGNGTFSIKKLRKDPPKHVTAKRVNMIAGGTGITPMLQLAREVLKRSDKDKTELALLFANQSEKDILLRAELDELAQKHPDQFKIWYTVDKANEAIKRMPRMGNARFVAWSYNTGHVNDDMMQQHLYPPGED-TLCLLCGPPPMVNYTCIPGLER-------LGHRAEQRFSY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38626-1", "uniprot_id": "NCB5R_YEAST", "id": "P38626-1", "name": "NADH-cytochrome b5 reductase 1", "aln": "MAIDAQKLVVVIVIVVVPLLF------------------KFIIGPKTKPVLDPKRNDFQSFPLVEKTILTHNTSMYKFGLPHADDVLGLPIGQHIVIKANINGKDITRSYTPTSLDGDTKGNFELLVKS--------YPTG-NVSKMIGELKIGDSIQIKGPRGNYHY----------------ERNCRSHLGMIAGGTGIAPMYQIMKAIAMDP-HDTTKVSLVFGNVHEEDILLKKELEALVAMKPSQFKIVYYLDS--------PDRED-----WTGGVGYITKDVIKEHLPAATMDNVQILICGPPAMVASVRRSTVDLGFRRSKPLSKMEDQVFVF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: **. : :**:** :.*:* ::**** ..*****:*::: : * ::.. : *.*** * * : * .:*::* :* * :::: : ::::*:.* ::** * * : :: ********:** *: : : . * * :*:*.* *:***:: **: : : .::.: * :* * * . *.:. ::::** .. . ::****.:: . . : *. : * :", "identical_positions": 71, "similar_positions": 88, "identity": "20.82%" }, { "cls_id": "homologset.agr.MGI:2444417", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9P6-1", "uniprot_id": "F1M9P6_RAT", "id": "F1M9P6-1", "name": "", "aln": "----MGGSQGSPDWRSQGPWPREDGAHMGGCFCIP---GERSLPWGPGKEGSSKDPPGLTEDISSLENK---RKCFLPQN---------------MTQDLVLSFWVRSRSRRCVNAALQEAARRRLWALENEAHEVHALFKDLSARLVSVQSQKDQFLITFKTLEEIWKFSTYLNLGYVSTCLEHLFFDHTYWLNSRLVDDTEIQVSVDDTHLENIYLGLLLQEGHFFCRAMCSVTQPADKEGEYLTLCKNELISVLSGGE-SDWEGMSLVTGQRGLVPVSALEPLPVSFHQWFLKNHPGICGLPRKKDWTGSCQIGRGRCKALMDYQQEERDELGFLQGESIDVIGFVIPGLRWFIGKSMSSGKVGFVPTRSIDLDSCSPVSKNSVFFSDEERCSLWSPGGDRKAECSGFLSALAHTDITSVYRLS-----EFESIQNLQNDLSASQPEGFREARSGGTWMERKTMGSRRS-SSSLDSS-LEDELISASSDSYHLPEPDDLDDPELFMDLSTSLEEDEMEHFAPILAFLDHEGYTDHFKSLYDFSFSFLTSSFYSFSEEDELVAYLETSRKWAKMTHRTWAHARLCFLLGRLSIRKTKLSQARVYFEEAIRVLDGAFEDLSLVAALYINLAAIYLRQRLRHKGPILLEKAGALLACLPDREFSAKNELDVVTYVLRQGIVAGSGPLEARSCFLAIRLLLNLGRHEEVLPFAERLQLLS-------GHSPASEVTATMLSSLYDKKYLPHLAVASVQKRGPQSARGMSVAIWQAYLVLQNATKILGVPFSSWCEVSALACPTLRQALAACEEQTDLNIQRTLCLLLSKMYLQHRSPDGSVQYLSQAHVLGKLLGEEEAFESSLCLAWAYLLARQTKKALEILEPLLCSLRETECVTQRGVVHNLLGLAFQDEGRTSRAAKSYLRALIRAREMGNIRNQAVSMANLGHLTLKSCMQQSARGYLLQAVRLYSEIQASKETDMELVQVLLWLGQALVSGHQLVHSRLCYEMALLFGLRHRHLNSQLQVTKSLCHFYSSVSPNPDACITYHEHWLALAQQLRDREMEGRLLESLGQLYRNLNTSRSLRRSLACIKESLRIFVDLGERDKAAEAWLGAGRLHYLMQEDELVEVYLQEAIQTALRSEELSLALKLYEEAGDVFFNGTRHRHRAVEYYRAGAVPLARRMKALRTELRIFNKLTELQISLRGYEKALEFATLAARLSVLTGDQKQELVAFHRLATVYFSLNMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYCRLGRLTFYQLKDAHDATEYFLLALAAAV----------------------LVGDEEL----------------------------------------------------------------------------QDTIKNRLDSICQSPLWHSKPLGCSSERSRWLSGGSLAL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VA5-1", "uniprot_id": "S3TC2_MOUSE", "id": "Q80VA5-1", "name": "SH3 domain and tetratricopeptide repeat-containing protein 2", "aln": "---------------------------MGGCFCIP---GERSLPWGPGKEGSSKDPPGLAEDTSSLENK---RKCFLPQN---------------MTQDLVLSFCVKSRSRRCVNAALQEAARRRLWALENEAQEVHALFKDLSARLVSVQSQKDQFLITFKTLEEIWKFSTYLNLGYVSICLEHLFFDHTYWLNSRLVDDTEIQVSVDDNHLENIYLGLLLQEGHFFCRAVCSVAQPADKEGEYLTLCKNELISVLSGGE-SECEAMSLVTGQRGLVPMSALEPLPVPFHQWFLKNHPGICGLPRKRDWTGSGQIGRGRCKALMDYEQEERDELCFLQGESIDVIGFVIPGLQWFIGKSVSSGEVGFVPTRSIDLDSCSPMSKNSAFFSDEERSSLWSPGSERKAECSGFLCSLAHTDITSIYRLS-----EFEAIQNLQNDLSASQPEGFREARSGGTWMERQTIGSRRS-SGSGDSSPEEDELISASSDSYHLPEPEDLDDPELFMDLSTSLEEDDVEHFAPILAFLDHEGYTDHFKSLYDFSFSFLTSSFYSFSEEDELVAYLETSRKWAKMSHMTWAHARLCFLLGRLSIRKTKLSQARVYFEEAIRVLDGAFEDLSLVAALYINLAAIYLRQRLRHKGPTLLEKAGALLACLPDHEFSTKNELDVVTYVLRQGIVVGSGLLEARSCFLAIRLLLSLGRHEEVVPFAERLQLLS-------GHPPASEATATMLSSLYDKKYLPHLAVASVQKRGPQSARGMSLSIWQAYLVLQNATKILGVPSSNWCEVSALACPTLRQALAACEELSDQDIQRTLCLILSKMYLQHQSPDGSVHYLSQAHVLGKLLGEEEAFESSLCLAWAYLLGRQTEKALEILEPLLCSLRETECVTQRGVVHNLLGLAFEDEGRTSRAAKSYLRALIRAREMGNIRNQAVSMANLGHLTLKSCMQQSARGYLLQAVRLYSELQASKETDMELVQVLLWLGQASVSGHQLVHSRLCYEMALLFGLRHQHLSSQLQVTKSLCHFYSSVSPNPDACITYHEHWLALAQQLRDREMEGQLLESLGQLYRNLNTSRSLRRSLACIKESLRIFVDLGERDKAAEAWLGAGRLHYLMQEDELVELYLQEAIQTALRSEEPSLALKLYEEAGDVFFNGTRHRHRAVEYYRAGAVPLARRMKALRTELRIFNKLTELQISLEGYEKALEFATLAARLSVLTGDQKQELVAFHRLATVYFSLNMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYCRLGRLTFYQLKDAHDATEYFLLALAAAV----------------------LMGDEEL----------------------------------------------------------------------------QNTIKNRLDSICQSPLWHSNPFGCSSERARWLSGGSLAL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF17-1", "uniprot_id": "S3TC2_HUMAN", "id": "Q8TF17-1", "name": "SH3 domain and tetratricopeptide repeat-containing protein 2", "aln": "---------------------------MGGCFCIP---RERSLTRGPGKETPSKDPTVSSECIASSEYK---EKCFLPQN---------------INPDLTLSFCVKSRSRRCVNGPLQEAARRRLWALENEDQEVRMLFKDLSARLVSIQSQRAQFLITFKTMEEIWKFSTYLNLGYVSMCLEHLLFDHKYWLNCILVEDTEIQVSVDDKHLETIYLGLLIQEGHFFCRALCSVTPPAEKEGECLTLCKNELISVKMAEAGSELEGVSLVTGQRGLVLVSALEPLPLPFHQWFLKNYPGSCGLSRKRDWTGSYQIGRGRCKALTGYEPGEKDELNFYQGESIEIIGFVIPGLQWFIGKSTSSGQVGFVPTRNIDPDSYSPMSRNSAFLSDEERCSLLALGSDKQTECSSFLHTLARTDITSVYRLS-----GFESIQNPPNDLSASQPEGFKEVRPGRAWEEHQAVGSRQS-SSSEDSS-LEEELLSATSDSYRLPEPDDLDDPELLMDLSTGQEE-EAENFAPILAFLDHEGYADHFKSLYDFSFSFLTSSFYSFSEEDEFVAYLEASRKWAKKSHMTWAHARLCFLLGRLSIRKVKLSQARVYFEEAIHILNGAFEDLSLVATLYINLAAIYLKQRLRHKGSALLEKAGALLACLPDRESSAKHELDVVAYVLRQGIVVGSSPLEARACFLAIRLLLSLGRHEEVLPFAERLQLLS-------GHPPASEAVASVLSFLYDKKYLPHLAVASVQQHGIQSAQGMSLPIWQVHLVLQNTTKLLGFPSPGWGEVSALACPMLRQALAACEELADRSTQRALCLILSKVYLEHRSPDGAIHYLSQALVLGQLLGEQESFESSLCLAWAYLLASQAKKALDVLEPLLCSLKETESLTQRGVIYNLLGLALQGEGRVNRAAKSYLRALNRAQEVGDVHNQAVAMANLGHLSLKSWAQHPARNYLLQAVRLYCELQASKETDMELVQVFLWLAQVLVSGHQLTHGLLCYEMALLFGLRHRHLKSQLQATKSLCHFYSSVSPNPEACITYHEHWLALAQQLRDREMEGRLLESLGQLYRNLNTARSLRRSLTCIKESLRIFIDLGETDKAAEAWLGAGRLHYLMQEDELVELCLQAAIQTALKSEEPLLALKLYEEAGDVFFNGTRHRHHAVEYYRAGAVPLARRLKAVRTELRIFNKLTELQISLEGYEKALEFATLAARLSTVTGDQRQELVAFHRLATVYYSLHMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYYRLGRLTFCQLKDAHDATEYFLLALAAAV----------------------LLGDEEL----------------------------------------------------------------------------QDTIRSRLDNICQSPLWHSRPSGCSSERARWLSGGGLAL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T7U2-1", "uniprot_id": "A0AB32T7U2_DANRE", "id": "A0AB32T7U2-1", "name": "", "aln": "MACCCCCCCPVPCLRNCFLFSAISPAELDALWNDPPYTLAAVSELFPPNDAMTADEEAEAEAEAEVEAEGISREIYWRRKETFSGSSTVSSSGERLSPDVVLLFSGRWRSSVAPDDQLQEALRTRLRVVESNSQDVVQLFKDLSARLLSVHAEKDSFVITFKTVEEIWKFSTYLALGYVARCLENFLCDQSFWLDPALLSDVEISVTVDEDHLATLYLGLLLQEGTFFGKTLY--KSDCKEEEEELNYRRNDLVMVKDIGQEAIWEGTLLSTGKHGLVPVHDMQPLPYPFYQWFLKKYPGNAGGISVTEGLFDHPVVVGTCVAVVDHYPVVKDELHLRIGDQIKIEGFLFNTLSMFIGRHLTSGETGFVHKAHVKPESTERLNGQLVFLSEEERTALSKLNPCLEPSQADVLTNLFSTDISTVYRLDRLDDSDFTYIRNHPIPEQKTTVDQRKRTVSEKSDATPYHSSPRQSFSASRNHLDRDSEVLSFNLEDTFREMDEYEEDPPNFMDEG-IWETEEAERCDPILTLLNLEYFQDTFRTLYDLSYSFLDTFFNGLPE-DEVLQHLENLREGAKKGRMLWAHRRACFLLGRLCAKKLKYSQARVYFEEASKVPVNGFNDKPLLIALYTNLTSVYLKQKMMDKLPFTLEKASALILCLPCHNFCSVDEFELLQPIMRRAIIEKDKYLEARTCYLSVCLFLHLRKIEEALPFVERLQFLIITLSVEEGRQIAPVDLNWLLCRLYHKKYLPFLALASLSLDSGQ-DHSLNDAFQKIELFIKNSVRLNPHWKENISVLPAQVVVYLQQALAIASQGEDLKTQRDLCLSLASVYQQHGALKKAVPYAQHAAKTGNQINEEEGFEASILLAWLLVMTDEPIQAQNNLRPLLKSLNETDSPTQRGVVYNLLALCLRKQARVQEAARNFYCALQISRENGNKRNEALALANLGCLSLSIGASGLAECFLLKSFHLFQFLSES-PTDQEHVQVLLWLGRSYKDRGGSQEVRLWFEMGLLIAISANNLHSQMVVAKVLSRHYADLLLYG-QCIVYYEHCVSLCRRLKNKQLEGEYLELLSSLYLSLNTEKSSRKSLDCSKQSLRISIDLGKRQEESETWLQVGRIYYLINEDELADMYLQAAVKTALRMNDPCFAMSIYEEAGDVFFKGHRNQIAALPFYRDGSLPFARSIKDVHSEFRLLSKLTELLMKQKQYEEALQYATLAVQVSATTGVLLNERASFHRLASVYFSLGKYEMAENYYLKSLSLCPTALEHAIEVRYYVKVYCRLADLTLYRLKDAFDAMGYFHLALAAALEDKESLSTLYIIYMKLAEIHANYMPDAELSKSYMDRAQSLRNELAGYTDSKDTEETDEADADIDNKSAHSDASSGTSTLTESSMINTSLTINAQKEPEHSNGSHKDDTNTNRSDETDSGPADHTNPETSCEDNANHSNGSTLKEGLTFVI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : * * :: : * :* :. * : .: : :: :. *:.* * : ** . : **** * ** .:*.: ::* *********:*::::: .*:*****:********** ****: ***::: *:.:**: *:.*.**.*:**: ** .:*****:*** ** ::: ..:* * *. :*:*: * : *. * **::*** : ::*** .*:*****::** .* : . : * * *: .: :*** : *:.*.: **:: * ***: :**:.*** . :. :* . :. : .*:*:*** :* . :.. :..* * ***:::***. * *:* . : : :.. . : ..*:* *.* : :.*::* . :. : :** :** . * : *. ***::*: * : * *::***:*:*** : * .:.* **.: :** *: ** : *** * *******. :* * ********** :: ..*:* .*: :** **:::**:*:: .* . ****.**: *** :: .: .*:::: ::*:.*: . ****:*:*:: *:* * : **.:**.****:* *: *. :*. **.*****.**:**:. . * :.:. .: : *.::*:.:: . :.* . *:**** ..: * . ** *** *:.:* :* : . :: * .:* *: :.*:*.**:*: *** :: :. :* : *.*** **.**:. *****::***.*.:. :.*...**:.: ** ::* *: :*:*:::**** *:*. . *. :**::.:*: :. * ** * ***:***.: . . * :**.**:.: .:* **: .:* *.:.*:.: **.*:** ::*.::*:::::**. ** *..** .*** :* *:** * *:**** :***: :: :*:** .**::**::****.:: ** *::***: :: :*:.:*********:* *:: *: :** *::*:** :* :::*:*::.***** :. . **:**::****.::*. ** :* .:*****:**:** *****: ***:*****. *: . *. **.*** **. **: :****.** ** ******: : * ** ::* .* *. ..* *:.* ...:.:. .*. * ", "identical_positions": 480, "similar_positions": 425, "identity": "32.99%" }, { "cls_id": "homologset.agr.MGI:2444418", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C850-1", "uniprot_id": "SCAR3_MOUSE", "id": "Q8C850-1", "name": "Scavenger receptor class A member 3", "aln": "MKVRSAGSDRDVLCVTEEDLAGEDEDMPSFPCTQEGRAGPRCNRCQKNLSLHTSVRILYLFLTLLLVAVAVLASLVFRKVDSLSEDISLAQSIYNKKLVSMQENLQGLDPKALINCSFCREAEQLGQEIRKVQEELEGLQKMLLAQEVQLDQTSQTHELLSTRSSQISQEMGSCSFSIHQVNQSLGLFLAQVRGWQATTAGMDITLKDLTQECYDVKAAVHQINFTVGQTAEWIHGIQRKTDEETLTLQKIVTDWQNYTRLFGGLRTTSAKTGEIVKTIQTTLGASSQRISQNSESMHDLVLQVMGLQLQLDNISSFLDDHEENMHDLQYHTRYAQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSLMLGTTDLLRERFSLLSARLDFNVRNLSMIMEEMKAVDTHHGEILRNVTVIRGVPGPPGPRGLKGDTGVKGPVGSRGPKGDPGNLGPPGPQGPQGQPGEPGPVGERGPAGPRGFPGLKGSKGSFGTGGPRGQPGPKGDVGPLGPEGPPGSPGPSGPQGKPGISGKTGSPGQRGATGPKGEPGIQGPPGLPGPPGPPGNQSPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZPA7-1", "uniprot_id": "D3ZPA7_RAT", "id": "D3ZPA7-1", "name": "", "aln": "MKVRSAGSDRDVLCVTEEDLAGEDEDMSSFPCSQEGRAGPRCNRCQKNLSLHTSVRILYLFLALLLVAVAVLASLVFRKVDSLSEDISLAQSIYNKKLVSMQENLQGLDPKALINCSFCREAEQLGQEIRKLQEELEGLQKMLLAQEVQLDQTSQAHELLSTTSSQISQEMGTCSFSIHQVNQSLGLFLAQVRGWQATTAGMDISLKDLTQECYDVKAAVHQINFTVGQTAEWIHGIQRKTDEETLTLQKIVTDWQNYTRLFGGLRSTSAKTGEIVKTIQATLGASSQRISQNSESMHDLVLQVMGLQLQLDNISSFLDDHEENMHDLQYHTRYAQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSLMLGTTDLLRERFSLLSARLDFNVRNLSMIMEEMKAVDTHHGEILRNVTIIRGVPGPPGPRGFKGDTGMKGPVGNKGPKGDPGSLGPPGPQGPQGQPGEPGPVGERGPAGPRGFPGLKGSKGSFGTGGPRGQPGPKGDVGPPGPEGPPGSQGPSGPQGKPGISGKAGSPGQRGATGPKGEPGIQGPPGLPGPPGPPGNQSPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6AZY7-1", "uniprot_id": "SCAR3_HUMAN", "id": "Q6AZY7-1", "name": "Scavenger receptor class A member 3", "aln": "MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYLFLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCHEAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQVNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRKTDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDLVLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTIFTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLLSARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QDK3-1", "uniprot_id": "E9QDK3_DANRE", "id": "E9QDK3-1", "name": "", "aln": "MKDSYCGYEN--QLFNEEDLTGEEEEIP----PLRGRARGGCMKCQQTHSLQLAVKMLYGFLALLIIAVAVLASLVFRRVDSLYEDE----SFYHKQMSKVEESVK--DIRTASNYSTCLDVAQFQEEIARLKKEFEEIQKTILSQEQQMNEATQSQQSLTQSSKRMARDFQALGMIIKSVNQSLSQYLNQVSGWQVVINETDHGMKTLVEDQHDLKATVQQVNTTVALSGLWIGALQRKAEEETLVLQKITADWQNYSRVLSTLKTNTSITMQNLRVVQNSISATQQRISTSSEMVHDLTLQVMNLQMQLDNVSSYIDEHEENMHDHQYHAKYYENRTGERFVTLDARMDSIEHEIDTISSSINATVNHVQSMYKYINMESSSCQSRLGSHTEDLQNLNNTVLLLLHLADTLRLQHMMLNERLENDVRSLTVVTEEMKLVDTSHAELIQNFTILKGLPGPPGPKGNRGESGAKGFGGLMGMKGERGIAGNRGPQGLKGSMGIKGDQGLLGVSGMKGGPGVKGEKGSLGQPGPRGEKGQKGDMGVSGKDGIPGPKGPTG------IRGQAGLPGVHGPSGTVGIPGPVGPPGPAGPPGPPGEAV--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .* : ..****:*::*::. . .**. * :**:. **: :*::** **:**::***********:**** ** *:*.*:: :::.:: * :: * * * :. *: ** ::::*:* :** :*:** *:::: *::: *: * :::::: : .: *:.*****. :* ** ***.. * :* *.:: :*:**:*:*:* **. :. ** .:***::****.****.:*****:*::. *::.:: * : :: :* ::.*:.**** .** :***.****.**:****:**::*:******* ***::* :*** *** :*:.** * * **.** :.**** ***:** **:: ** : :*:*:* **::* ::* :* ** :. :*. **: :**.*::: **** *** *.*:::*.*:::* ******:* :*: * ** * * **: * * **** :*. * * * * * :* **:**.***:* ****: * ***:* * :* **. **:* * *::* ** :*. *. * ** **** .*******. ", "identical_positions": 269, "similar_positions": 177, "identity": "44.39%" }, { "cls_id": "homologset.agr.MGI:2444421", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZV82-1", "uniprot_id": "D3ZV82_RAT", "id": "D3ZV82-1", "name": "", "aln": "---------------MASASSMEAPICLVENENEELRVNPKAINILERITQPVVVVAIVGLYRTGKSYLMNRLAGQNHGFNLGTTVRSETKGIWMWCVPHPCKPKFTLVLLDTEGLGDVEKCDPKNDSWIFALAVLLSSTFVYNSMSTINHQALEQLHYVTELTELIRTKSTPRSEEIDDSDEFVGFFPDFIWVVRDFVLELKLDGRVITADEYLENALKLIPGRSLKAQNSNLPRECIRHFFPRRKCFVFDRPIKEKELLVHVEEMPEDELDHNFREQSNVFCSYIFSNAKAKTLKEGIMVNGNRLATLVTTYVDAINSGAVPCLENAVTTLAQRENSAAVQKAAEHYSEQMAQRLRLPTDTLQELLDVHSACEKEAIAVFMEHSFKDENQEFQKNLVVTIVEKREDFSRQNEAASLSHCQAELDKLSESLRESISCGAFSVPGGHSLYLEARKKVEQDYEQVPRKGVKANHVLQSFLQSQIVIENSILQSDKALTVNQKAMEVERAQKEAAEKEQELLRQKQKELQQVMESQERSYKENIVQLHEKMETERKNILEKQEEMLAHKLKVQEEMLNEGFKRKYEAMDSEISQLQKQIQQNKEQNSSLAAQIFDGFGNVLMSVLPGTGKLFGLGLKILSRKMK-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Z40-1", "uniprot_id": "GBP7_MOUSE", "id": "Q91Z40-1", "name": "Guanylate-binding protein 7", "aln": "---------------MASGPNMEAPVCLVENENEELRVNSKAINILERITQPVVVVAIVGLYRTGKSYLMNRLAGQNHGFNLGTTVRSETKGIWMWCVPHPSKPKFTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLSSTFVYNSMSTINHQALEQLHYVTELTERIRAKSTSRSEEVDDSDEFVSFFPDFIWTVRDFVLELKLEGRVITADEYLENALKLIPGMSIKAQKANLPRECIRHFFPRRKCFVFDRPTKDKELLVHVEEMPEDQLDHSFQVQSKEFCSYIFSNSKAKTLKEGIVVNGNRLATLVTTYVDAINSGDVPCLENAVTTLAQRENSIAVQKAADHYSEQMAQRMRLPTDTLQELLTVHTACEKEAIAVFMEHSFKDENQQFQKNLVVTIEEKKEDFLRQNEAASLSHCQAELDKLSESLRESISRGVFSVPGGHRLYLEARKKVEQDYERVPRKGVKANHVLQSFLQSQISIEDSIMQSDKALTDGQKAMEAERAQKEAAEKEQELLRQKQKELQQVMEAQERSYKENVAQLHEKMETERKNILREQEVKLEHKLKIQKDMLNEGFKRKCEAMDLEISQLQKEIQLNKEKNSSLGAKILDGFGDVLISVVPGSGKYFGLGLKILSSQMNQTQNSDKVRKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PP9-1", "uniprot_id": "GBP4_HUMAN", "id": "Q96PP9-1", "name": "Guanylate-binding protein 4", "aln": "MGERTLHAAVPTPGYPESESIMMAPICLVENQEEQLTVNSKALEILDKISQPVVVVAIVGLYRTGKSYLMNRLAGKRNGFPLGSTVQSETKGIWMWCVPHLSKPNHTLVLLDTEGLGDVEKSNPKNDSWIFALAVLLSSSFVYNSVSTINHQALEQLHYVTELAELIRAKSCPRPDEAEDSSEFASFFPDFIWTVRDFTLELKLDGNPITEDEYLENALKLIPGKNPKIQNSNMPRECIRHFFRKRKCFVFDRPTNDKQYLNHMDEVPEENLERHFLMQSDNFCSYIFTHAKTKTLREGIIVTGKRLGTLVVTYVDAINSGAVPCLENAVTALAQLENPAAVQRAADHYSQQMAQQLRLPTDTLQELLDVHAACEREAIAVFMEHSFKDENHEFQKKLVDTIEKKKGDFVLQNEEASAKYCQAELKRLSEHLTESILRGIFSVPGGHNLYLEEKKQVEWDYKLVPRKGVKANEVLQNFLQSQVVVEESILQSDKALTAGEKAIAAERAMKEAAEKEQELLREKQKEQQQMMEAQERSFQEYMAQMEKKLEEERENLLREHERLLKHKLKVQEEMLKEEFQKKSEQLNKEINQLKEKIESTKNEQLRLL-KILDMASNIMIVTLPGASKLLGVGTKYLGSRI------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8N8V2-1", "uniprot_id": "GBP7_HUMAN", "id": "Q8N8V2-1", "name": "Guanylate-binding protein 7", "aln": "---------------MASEIHMPGPVCLTENTKGHLVVNSEALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKNKGFPLGCTVKSETKGIWMWCVPHPSKPNHTLILLDTEGLGDMEKSDPKSDSWIFALAVLLSSSFVYNSMGTINHQALEQLHYVTELTELIRAKSCPRPDEVEDSSEFVSFFPDFIWTVRDFTLELKLDGHPITEDEYLENALKLISGKNPQIQNSNKPREWIRHFFPKQKCFVFDRPINDKKLLLHVEEVREDQLDSNFQMQSENFCSYIFTHAKTKTLREGILVTGNRLGMLVETYLDAINSGATPCLENAMAVLAQCENSAAVQRAANHYSQQMAQQVRFPTDTLQELLDVHAVCEREAIAVFMEYSFKDKSQEFQKKLVDTMEKKKEDFVLQNEEASAKYCQAELKRLSELLTESISRGTFFVPGGHNIYLEAKKKIEQDYTLVPRKGVKADEVLQSFLQSQVVIEESILQSDKALTAGEKAIAAKQAKKEAAEKEQELLRQKQKEQQQMMEAQERSFQENIAQLKKKMERERENYMRELRKMLSHKMKVLEELLTEGFKEIFESLNEEINRLKEQIEAAENEEPSVFSQILDVAGSIFIAALPGAAKLVDLGMKILSSLCNRLRNPGKKIIS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * .*:**.** : .* **.:*::**. *:*********************:***:.:** ** **:************* .**:.**:*********:** :**.*************:*****:.****************:* **:** .*.:* :**.**..*******.****.*****:*. ** ***********.* . : *::* *** ***** ::******** ::*: * *::*: *::*: * **. ******:::*:***:***:*.*:**. ** **:****** .******::.*** **. ***:**:***:****::*:********* **:.**:********:****:.::***:** *: :*: ** *** ** .:*****.:*** * *** * * ***** :*** :*::* ** ********:.***.*****: :*:**:******* .:**: .::* ************:**** **:**:****::* :.*:.:*:* **:* :.: . * **:*: :::*.* *:. * :: **.:*:::*: :::: : :*:* ..::: .:**:.* ..:* * *. ", "identical_positions": 373, "similar_positions": 162, "identity": "57.12%" }, { "cls_id": "homologset.agr.MGI:2444426", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ASV5-1", "uniprot_id": "A0A8I6ASV5_RAT", "id": "A0A8I6ASV5-1", "name": "", "aln": "-------------------------------------------MKKHS----ARVAPLS-------------------------------ACNSPVLTLT----------KVEGEERPR--EPPGPAEAQAP---AGTEAGGRTS--RHHWT-CSQEQLRKVFWGVAVVFCVCASWSGSTQLARLTFKT-------------------------------------------------------FDAPFTLTWFATNWNFLFFPLYYAGHVCKSTEKQSVKQRYRECCRFFGDNGLTLKVFFTKAAPFGVLWTLTNYLYLHAIKKINATDVSVLFCCNKSFVFLLSWIVLRDRFMGVRIVAAILAIAGIVMMTYADGFHS-HSVIGIALVVGSASMSALYKVLFKLLLGSAKFGEAALFLSILGVFNILFITCIPIILYFTRVEYWNSFDDIPWGNLCGFSILLLTFNIVLNFGIAVTYPTLMSLGIVLSVPVNAVVDHYTSQIVFNGVRVIAIIIIGLGFLLLLLPEEWDVWLIKLLTR--------------LKVRKK-EETAESSGDLGTGPQSRSRRARPSFAR-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q1LZI2-1", "uniprot_id": "S35F3_MOUSE", "id": "Q1LZI2-1", "name": "Solute carrier family 35 member F3", "aln": "-------------------------------------------MKKHS----ARVAPLS-------------------------------ACNSPVLTLT----------KVEGEERPR--EPPGPAEAQAP---AGTEAGGRTS--RHNWT-CSQERLKKVFWGVAVVFCVCASWAGSTQLARLTFKT-------------------------------------------------------FDAPFTLTWFATNWNFLFFPLYYAGHVCKSTEKQSMKQRYRECCRFFGDNGLTLKVFFTKAAPFGVLWTLTNYLYLHAIKKINATDVSVLFCCNKSFVFLLSWIVLRDRFMGVRIVAAILAIAGIVMMTYADGFHS-HSVIGIALVVGSASMSALYKVLFKLLLGSAKFGEAALFLSILGVFNILFITCIPVILYFTRVEYWNSFDDIPWGNLCGFSILLLTFNIVLNFGIAVTYPTLMSLGIVLSVPVNAVVDHYTSQIVFNGVRVIAIIIIGLGFLLLLLPEEWDVWLIKLLTR--------------LKVRKK-EETAESSGDLGTGPQSRSRRARPSFAR-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IY50-1", "uniprot_id": "S35F3_HUMAN", "id": "Q8IY50-1", "name": "Solute carrier family 35 member F3", "aln": "-------------------------------------------MKKHS----ARVAPLS-------------------------------ACNSPVLTLT----------KVEGEERPR--DSPGPAEAQAP---AGVEAGGRAS--RRCWT-CSRAQLKKIFWGVAVVLCVCSSWAGSTQLAKLTFRK-------------------------------------------------------FDAPFTLTWFATNWNFLFFPLYYVGHVCKSTEKQSVKQRYRECCRFFGDNGLTLKVFFTKAAPFGVLWTLTNYLYLHAIKKINTTDVSVLFCCNKAFVFLLSWIVLRDRFMGVRIVAAILAIAGIVMMTYADGFHS-HSVIGIALVVASASMSALYKVLFKLLLGSAKFGEAALFLSILGVFNILFITCIPIILYFTKVEYWSSFDDIPWGNLCGFSVLLLTFNIVLNFGIAVTYPTLMSLGIVLSIPVNAVIDHYTSQIVFNGVRVIAIIIIGLGFLLLLLPEEWDVWLIKLLTR--------------LKVRKK-EEPAEGAADLSSGPQSKNRRARPSFAR-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QKB7-1", "uniprot_id": "A0A8M9QKB7_DANRE", "id": "A0A8M9QKB7-1", "name": "", "aln": "-----------MGIMYGDGDRLGPPRRDCMCYLGPPTTLMPIGMRRSPEVSPRRLSDISPQLRQLKYLVVDESIKEDLKSSRSVEDINSASIEERILRITGYYGYQPWNAVYKREDRPR-ENVVGTADGQAMVGGAGVESGAGRQRLRCCVR-VTAVQVRKAIWGVAMVMCVCSSWAGSTQLAKLTFKK-------------------------------------------------------YDAPFTLTWFATTWNCLFFPLYYIGHLCKSPERQTPKQRFRECCRFFGDDGLTAKVFFTKVAPFGLLWILTNYLYLQALRKINSTDVSALFCCNKAFVFLLSWIVLRDRFMGVRIVAAILAIAGIVMLTYADGFHS-HSVIGITLVVASASASALYKVLFKLVLGSAKFGEAALFLTIVGGANFIFMSFVPVLLYFTHVEYFTSFADLPWACMCGVAALLLAFNILVNFGIAITYPTLISLGIVLSVPVNAMVDLYTCDIHFNTVRLIAVCIICLGFLMLLLPEDWDQCLIELGTK--------------LRKREQPAEPADGGNSSGLNWTRRARTSMSTFTH-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1RDU1-1", "uniprot_id": "F1RDU1_DANRE", "id": "F1RDU1-1", "name": "", "aln": "-----------MQKEDETPLQLQGPQKD-------------RGMRKPSDMSPRRLSDISPQIRQLKSLVLDEDLNEELKSSRSVEYIQNASIEERILRITGYYGYEPWSASVRGEEQSSSEKVEVKVDGHS--GTALLDCADRLQRLRCCLH-LTAVHLRGALWGVAMVICICMSWSGSTQLAKITVRR-------------------------------------------------------LNIPFTLTWFSTSWNCAIFPVYYLGHLCWSKDRQTPRQRFRECCQFLGDDGLSLKMLLSRVAPFGVLWTLTSYLYLQGLRRIPATDACALFCCSRAFVFLISWIVLRDRFMGVRIVAAVLAIGGIVMMTYADGFHS-YSVIGISLVVGSASTAAIYKVLFKLVLGSAKLGEAAVYLTILGGANLIFISAVPLILLLTGAEDFISPRDLPWSSICGMSALLLVFNFLLNCGVLITLPTLISLGVVLSVPVNAVIDRYMYDIQLNSVRVIAVSIICLGFLLLLLPEDWDQCLPQLRSI--------------LHSRRQPQESARDKHSEMLHIRPREAKNCNSKTTGVR----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A4V362-1", "uniprot_id": "A4V362_DROME", "id": "A4V362-1", "name": "Solute carrier family 35 member F4", "aln": "MTRDGEIPAIFNPKRVRTPSVVVTGDSSTNGPYSNNSTGGAGASSSTAVAPGSSAQNGGSGSGAAGSCGFSNVLTSSNPQITHQDSISSSQQDPNEVVIIPADTPTSAPGSHNAAHHFGGGDSSDTQTEQQQANGHGEESELRFRKLQACKESCCSELARKMYFGVCVTILMTASWVGATHCIKYMYKYRAPYDDLLNDDQDTSSSRADLSTELEDILAISDSSLHHVEDATEMFNIPPRQPVYFSAPFFAAWFFTNFSLLFFPIYLLGLVS-TRKCEKLSDILGDVLRGFRERGFTVGRFLNRCLCFCILWLVTTYLYTLSLHVLYATDALALFATNVACVYLLSWVILHEQFVGVRIVAIILCDTGIALLAYMDGITESRTLSGVVLATLAGAGYAVFRVMFRKVMGDPPVSQIAFIFTALGFLNALLLWPVVLGLYLTGTESLTS-ESIPWNLLFAASLLLLVFHVLMQFSAAVTYNMFVTLGLITAVPVSGALDVILYSANFAGMKLAGVILIGIGFFLVMFPANWPDYITRLLRKSVRAILRYQCCCELAEIRYAHSKHHNAGSQCEMGSRPSERYFNRSASHHYRLSDGIHKVPSSFTLWPCEMTDLSPTTSGFLHGHGGANAQHHQQLLHHQQQQHQQTHQQHLQQQYHHRQHSLHQQHLQRQHSHTSLTKIHRQSSSHSVHGGGGRADHHRTTTGATGRLFSYFGNEQDHERKKSETSFFNLGFRRKSTVVYYAPAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : : . .: . : :. : : :**.:.: : ** *:*: : : . ** :** *.:. :**:* * :. : . :. : : : : : *:: ::.: * :** :*.*** .:: : :**. .**. . : *:*:**::*:::*:****** :*. **.:::* **: . :: *: *.. :.: *:::*:*: ::*.. ..: *. :: :* * ::: : : * :* .* * .:** : . : ***.*:.::: . :* :::**:: ::**.. :* . : ::: .: :* :**:::::* :* : .* . * : . : : ", "identical_positions": 77, "similar_positions": 153, "identity": "10.34%" }, { "cls_id": "homologset.agr.MGI:2444430", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGQ4-1", "uniprot_id": "POMT2_MOUSE", "id": "Q8BGQ4-1", "name": "Protein O-mannosyl-transferase 2", "aln": "MLYASGRLLAARAATTLSAPPRARGPALRGKRRELQIPWHLETPSYDPLTGQRTRPGVPPARRVILRKGRMPPAIGGGLAGSELRPRRGRCVPQAARAVSRDVVPQAAARKLKRPAWSSRRFQAAGWWATLAVVTLLSFATRFHRLDQPAHICWDETHFGKMGSYYINRTFFFDVHPPLGKMLIGLAGYLSGYDGTFLFQKPGDRYEHHSYMGMRGFCAFLGSWLIPFAYLTVLDLSKSFPAALLTAALLTFDTGCLTLSQYILLDPILMFFIMAAMLSMVKYN--SCANRPFSAPWWFWLSLTGISLAGALGVKFVGLFIIVQVGLNTISDLWHLFGDLSLSLVTVGKHLTARILCLIVLPLVLYVTIFAVHVMVLNKSGPGDGFFSSAFQARLSGNSLHNASIPEHLAYG-SVITVKNLRMAIGYLHSHRHLYPEGIGARQQQVTTYLHKDYNNLWIIKKYNA----NTDPLDPSFPVEFVRHGDIIRLEHKETTRNLHSHYHEAPLTRKHYQVTGYGINGTGDSNDFWRIEVVNRK----------FGNRIKVLRSRIRLIHLVTGCVLGSSGKILPKWGWEQLEVTCTP-YLKETTNSIWNIEEHINPKLP--NISLDVLQPSFPEILLESHMVMIRGNNGLKPKDNEFT---SKPWHWPINYQGLRFSGANDTDFRVYLLGNPVVWWLNLVSIVLYLLSGSTIAVAMQRGIQLPAELQG-----------------------------------------------LTKVLLRGGGQLLLGWMLHYFPFFLMGRILYFHHYFPAMLFSSMLTGILWDTLLRLCAWGLAPSPLGRRIHAVGILSLLLTTAYSFYLFHPLAYGMVGPLAQEPESPMAGLRWLESWDF-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14U74-1", "uniprot_id": "Q14U74_RAT", "id": "Q14U74-1", "name": "Dolichyl-phosphate-mannose--protein mannosyltransferase", "aln": "MFYASGRLLAAREATTLYAPPRARGPALRGKRRELQIPWHLETPSYDSLTGQRTRPGVPPARRVILRKGRMPPAIGGGLAGSELRPRRGRSVQQAARAVSRDVVPEAATRKLKRPAWSSRRFQAAGWWATLAVVTLLSFATRFHRLDQPAHICWDETHFGKMGSYYINRTFFFDVHPPLGKMLIGLAGYLSGYDGTFLFQKPGDRYEHHSYMGMRGFCAFLGSWLIPFAYLTVLDLSKSFPAALLTAALLTCDTGCLTLSQYILLDPILMFFIMAAMLSMVKYN--SFANRPFSAPWWFWLSLTGISLAGALGVKFVGLFIIVQVGLNTISDLWHLFGDLSLSLVTVGKHLTARILCLIVLPLVLYVTIFAVHVMVLNKSGPGDGFFSSAFQARLSGNSLHNASIPEHLAYG-SVITVKNLRMAIGYLHSHRHLYPEGIGARQQQVTTYLHKDYNNLWIIKKYNT----NTDPLDPSFPVEFVRHGDIIRLEHKETTRNLHSHYHEAPLTRKHYQVTGYGINGTGDSNDFWRIEVVNRK----------FGNRIKVLRSRIRFIHLVTGCVLGSSGKILPKWGWEQLEVTCNP-YLKETSNSIWNIEEHINPKLP--NISLDVLQPSFPEILLESHMVMIRGNNGLKPKDNEFT---SKPWHWPINYQGLRFSGANDTDFRVYLLGNPVVWWLNLVSLVLYLLTGSTIAIAMQRGIQLPAELQG-----------------------------------------------LTKLLLRGGGQLLLGWTLHYFPFFLMGRVLYFHHYFPAMLFSSMLTGLLWDTLLRFCAWALAPSPLGRRIHMVGILSLLLATAYSFYLFHPLAYGMVGPLAQEPESPMAGLRWLESWDF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UKY4-1", "uniprot_id": "POMT2_HUMAN", "id": "Q9UKY4-1", "name": "Protein O-mannosyl-transferase 2", "aln": "----------------------------------------------------------------------MPPATGGGLAESELRPRRGRCGPQAARAAGRDVAAEAVARSPKRPAWGSRRFEAVGWWALLALVTLLSFATRFHRLDEPPHICWDETHFGKMGSYYINRTFFFDVHPPLGKMLIGLAGYLSGYDGTFLFQKPGDKYEHHSYMGMRGFCAFLGSWLVPFAYLTVLDLSKSLSAALLTAALLTFDTGCLTLSQYILLDPILMFFIMAAMLSMVKYN--SCADRPFSAPWWFWLSLTGVSLAGALGVKFVGLFIILQVGLNTIADLWYLFGDLSLSLVTVGKHLTARVLCLIVLPLALYTATFAVHFMVLSKSGPGDGFFSSAFQARLSGNNLHNASIPEHLAYG-SVITVKNLRMAIGYLHSHRHLYPEGIGARQQQVTTYLHKDYNNLWIIKKHNT----NSDPLDPSFPVEFVRHGDIIRLEHKETSRNLHSHYHEAPMTRKHYQVTGYGINGTGDSNDFWRIEVVNRK----------FGNRIKVLRSRIRFIHLVTGCVLGSSGKVLPKWGWEQLEVTCTP-YLKETLNSIWNVEDHINPKLP--NISLDVLQPSFPEILLESHMVMIRGNSGLKPKDNEFT---SKPWHWPINYQGLRFSGVNDTDFRVYLLGNPVVWWLNLLSIALYLLSGSIIAVAMQRGARLPAEVAG-----------------------------------------------LSQVLLRGGGQVLLGWTLHYFPFFLMGRVLYFHHYFPAMLFSSMLTGILWDTLLRLCAWGLASWPLARGIHVAGILSLLLGTAYSFYLFHPLAYGMVGPLAQDPQSPMAGLRWLDSWDF-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q8R9-1", "uniprot_id": "POMT2_DANRE", "id": "F1Q8R9-1", "name": "Protein O-mannosyl-transferase 2", "aln": "----------------------------------------MDVRPKENFS--------------------QRQDTSAVRHRKTCKVNERAEIPSQPHNGTINGVNKRITKREGGEHISSPSRDAHVPVFILALVIVLSVSTRFYKITEPPHVCWDETHFGKMGSYYINRTFFFDVHPPLGKMLIGLAGYLTGYDGTFPFIKPGDKYEHHNYWGMRAFCAALGSCLPPFAFLVVLELSQSSTAALIAASLLIFDTGCITLSQYILLDPILMFFIMGSVLCMVKFN--TQRLGPFSFSWWFWLLLTGLCLSGSLGVKFVGLFVILLVGINTALDLWRLLGDLSLSLVDFGKHLLARVFGLIMLPLFLYTTIFAIHFIVLNRSGPGDGFFSSAFQSRLIGNNLHNASMPEYLAYG-SVITVKNLRIAGGYLHSHWHLYPEGVGAHQQQVTAYLHKDYNNLWLVKRLD-----NSDDLTGSP--ELVRHGDIIRLEHKETTRNLHSHFHEAPLTKKHLQVTGYGINGSGDVNDLWQVEVCGGR----------KGDPVKVLRSKVRFLHRATGCVLCSSGKTLPKWGWEQVEVTCSP-YVKETPNSQWNIEDHINPKLP--NISLAVLKPTFLEILWESHIVMIRGNSGLKPKDNEMN---SKPWHWPINYQGLRFSGVNETEYRVYLLGNPVIWWLNLLSLALFVILLTVASLAVQRRVKMEGMMKV-----------------------------------------------HCHTLMEGGGMLFLGWLLHYLPFYIMGRILYYHHYFPAMMFSSMLTGITLDILLQNLQLLFSSS-LSHYLMRGGQSVLLLGFIYSFYLFHPLSYGMRGPLAHDSASSMAGLRWMESWEF-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W5D4-1", "uniprot_id": "POMT2_DROME", "id": "Q9W5D4-1", "name": "Protein O-mannosyl-transferase 2", "aln": "------------------------------------------------------------------------------MAASVVKT------PKCPRRGSVKDVAQNAPRTAP----TSSKEANWNWWLLLATVFLVTFATRFYKVTEPDHICWDETHFGKMGSWYINRTFFFDVHPPLGKMLIGLSGYLTGYNGTFPFEKPGDKYNETRYQGMRYFCTTLGALIMPMGFDTVYDLTRSHEAALLAAAYLIFDVGLLTLNQYILLDPILLFFMMASVWGMVKVSKSTASGGSYGLRWWLWLFLTGTMLSCTISVKFVGLFVVLLVGLHTATELWLILGDLGQPILETVKQLACRAITLIVWPVLLYILFFYIHLSVLNRSGNGDGFYSSAFQSRLIGNSLYNASMPRDVAYG-SLVTIKNHKTGGGYLHSHHHLYPKGSGARQQQVTTYTHKDENNKWLIRPHN-------KPGPPKGKVQILRHGDLVRLTHMATRRNLHSHNEPAPMTKKHLQVTGYGELGLGDANDVWRVLIVGGK----------VNETVHTVTSRLKFIHLLQNCALTSSGKQLPKWGFEQQEVSCNP-NVRDK-NSQWNVEDNEHKLMP--SVSFSVYAPGFFARFLESHAVMLQGNAGLKPKEGEVT---SRPWQWPINYRGQFFSGS---SYRIYLLGNPLIWWSNLVFLALFVTVFLCNAVVQQRRAGFARSAAQNQAQVPDSETVAQDEESEHSTTDICSCCTPAKEIVPKAVPSGSPEAPNPAQSLRAAAWLFLGWMLHYLPFWAMGRVLYFHHYFPALIFNSLLTGVMYNYILR---------VLPKWIHHVILGLVLSILVYSFAAFSPLAYGMSGPLANEPNSTMYNLKWLSTWEF-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47190-1", "uniprot_id": "PMT3_YEAST", "id": "P47190-1", "name": "Dolichyl-phosphate-mannose--protein mannosyltransferase 3", "aln": "----------------------------------------MPYRVATGYSEK-----------------------STDDDLIWRTP-----IVKEELEDADNFLKDDAELYDKVK--NESAVSHLDTIVMPIIFTVLGMFTRMYKIGRNNHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEVYPDYIDYVKMRLFQAMFSSLCVPLAYFTGRAIGFSRLSVWLFTILVIFENSYATLGKFILLDSMLLFFTVSSYFCLAKFH--TMRKSPFSARWWLWLCLTGLNLGCAISVKMVGLFIISVVGIYTISELWNLLSDRSVSWKVYVNHWLARIFGLIIIPVCVFLLCFKIHFDLLSNSGPGDSTMPSLFQASLNGTKVGKG--PRDVALGSSIISIKNQALGGALLHSHVQPFPEG--SEQQQVTVYGYSDANNEWFFQRIR--GVEP-WTDAENKTIEFVKGGEMYRLMHRLTGKNLHTHEVPAPISKSEYEVSAYGDVDLGDYKDNWIIEIVEQV-------GEEDPTLLHPLSTSFRIKNSILGCYLAQSGKHLPEWGFRQGEVVCLKHASKRDKRTWWNIETHENERLP-QGEDFVYPKTSFFRNFMQLNSAMMATNNALVPNPEKFDGIASSAWQWPTLNVGVRLCEWSEKSIKYFLLGSPASVWPSSIAVCALIIHVIFLTLKWQRQCVILSDPVE------------------------------------------------RDVFVMAAFYPLLAWLLHYMPFVVMSRVVYAHHYLPTLYFALMILSYYFDMITKRWAT----RNTGKFLRLGAYIVYGSIVIAGFFYFSPFSFGMDGPVDD-----YAYLAWLPTWQIVEDIRNT", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P31382-1", "uniprot_id": "PMT2_YEAST", "id": "P31382-1", "name": "Dolichyl-phosphate-mannose--protein mannosyltransferase 2", "aln": "----------------------------------------MSSSSSTGYSKNNA------------------AHIKQENTLRQRESSS--ISVSEELSSAD---ERDAEDFSKEKPAAQSSLLRLESVVMPVIFTALALFTRMYKIGINNHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEIYPDYLDYVKMRLFNASFSALCVPLAYFTAKAIGFSLPTVWLMTVLVLFENSYSTLGRFILLDSMLLFFTVASFFSFVMFH--NQRSKPFSRKWWKWLLITGISLGCTISVKMVGLFIITMVGIYTVIDLWTFLADKSMSWKTYINHWLARIFGLIIVPFCIFLLCFKIHFDLLSHSGTGDANMPSLFQARLVGSDVGQG--PRDIALGSSVVSIKNQALGGSLLHSHIQTYPDG--SNQQQVTCYGYKDANNEWFFNRER--GLPS-WSENE-TDIEYLKPGTSYRLVHKSTGRNLHTHPVAAPVSKTQWEVSGYGDNVVGDNKDNWVIEIMDQR-------GDEDPEKLHTLTTSFRIKNLEMGCYLAQTGNSLPEWGFRQQEVVCMKNPFKRDKRTWWNIETHENERLPPRPEDFQYPKTNFLKDFIHLNLAMMATNNALVPDPDKFDYLASSAWQWPTLNVGLRLCGWGDDNPKYFLLGTPASTWASSVAVLAFMATVVILLIRWQRQYVDLRNPSN------------------------------------------------WNVFLMGGFYPLLAWGLHYMPFVIMSRVTYVHHYLPALYFALIILAYCFDAGLQKWSR----SKCGRIMRFVLYAGFMALVIGCFWYFSPISFGMEGPSSN-----FRYLNWFSTWDIADKQEA-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P42934-1", "uniprot_id": "PMT6_YEAST", "id": "P42934-1", "name": "Dolichyl-phosphate-mannose--protein mannosyltransferase 6", "aln": "----------------------------------------MSKAKGTGFSSID----------------------TEDENLRERYVNQPKANASDIQDEQLDCFEQLEEKHRTKKNEEYTALKILRDVIGPLLLTITSFYLRFQHIDQNNYVVWDEAHFGKFGSYYIKHEYYHDVHPPLGKMLIALSEWMAGFDGQFDFSSNNAYPENVNFKLMRQFNATFGALCTPVAFFTAKWMGFNYFTVYLIATMVTLEHSYIVLSKFILLDSMLLFFSMTTFACMIKLY--TLRKQQMTKKWSLWMLLTGLSIGCVCSVKWVGLFITVVVGLYTCIELFLLYCDKELPRIKYYKHWLIRIINLIVIPFLIYLYCFKIHFVLLYKSGTGDSTTNTLFQINLEGTQIEAG--PRDVAFG-SELTIRSHGLSPNLLHSHIQVYPEG--SGQRQITGYGFADSNNVWKFEFSRSSGLELDQNGTLNGKIIPITDGVEVRLSHKNTGSNLHSHDVPSHVSRGNYEVSGYGSQSVGDEKDDWIVEIVKQMDSPNPVYSNENSTILHPVSTFFRLRHKVLGCYLASTGLTYPAWGFKQAEIVCKDSWSRRDKSTWWNVEDHWNHNLE-TAEDYVPPKSNFWTDFILTNFAMASSNNALVPDEDKYDSLSSDAWEWPTLHKGLRMCSWAGYITRYYLMGSPFNTWISTVSLIIFPFIILFILYRWRRQTLYLSDDQI------------------------------------------------WQITIQG-IFPFISWMTHYLPFAMMGRVTYVHHYVPALYFAMLVFGFVLDFTLTRVH---------WMVKYPIYLSLFGGCIYIYNLFAPICQGMHGDKAE-----YLPLQWLSTWDIAP-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . *: :: :: ***:****:**:*:.: ::.**********:.*: :::*::* : * . : : ** * : :.: *..: . : . :. : : : : . .*.::****.:*:** : : : . * *: :** :. .** ****: **: * :*: : * . :: * : **: *. :: * :*. :* .** **. : ** * *..: . *. :* * * ::::. . **** : :*.* : *:*:* * . * ** * .. : * ** * * ***:* : ::: . :*:.** ** :* * : : :: : : .:: : .* * .:* * **:.* *: * : : **:* : : : . . * : : .* * .* *. : * .*.** * :. : :*:*.* * . : : :* : . ::.* **:** *.*: * ***.*:: * :: . : : : * *:. ** * . * *: :*:: ", "identical_positions": 149, "similar_positions": 179, "identity": "16.61%" }, { "cls_id": "homologset.agr.MGI:2444431", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75154-1", "uniprot_id": "RFIP3_HUMAN", "id": "O75154-1", "name": "Rab11 family-interacting protein 3", "aln": "--MASAPPASPPGSEPPGP---DPEPG-----GPDGPG-----------------------AAQLAPGP----AELRLGAPVGGPDPQSPGLDEPAPGAAADGGARWSAGPAPGLEGG------PRDP-----------GPSAP----------------------------PPRSGPRG---------QLASPDAPGPGPRS-----------EAP-------------------LPELDPLFSWTEE---PEE---------------------------------------------CGP-----------------ASCPESAPFR---------------------LQGSSSSHRARGEVD-----------------------------------------------------------------------------VFSPFPAPTAGELALEQGPGS------------------------------------------------------------PPQPSDLSQTHPLPSEPVGSQEDGPRLRAVFDALDGDGD----GFVRIEDFIQFAT-VYGAEQVKDLTKYLDPSGLG-------VISFEDFYQGITAIRNGDPDGQCYGGVASAQ--DEEPLACPDEFDDFVTYEANEVTDSAYMGSESTYSECETFTDEDTS-------TLVHPELQPEGDADSAGGSAVPSECLDAMEEPD---HGALLLLPGRPH-------------PHGQSVI---------TVIGGEE----HFEDYGEGSEAELSP--------------ETLCNGQLGCSDPAFLTPSP-------------------------TKRLSSKKVARYLHQSGALTMEALEDPSPELMEGPEEDIADKVVFLERRVLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDE-------------LMEAIQKQEEINFRLQDYIDRIIVAIMETNPSILEVK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CHD8-1", "uniprot_id": "RFIP3_MOUSE", "id": "Q8CHD8-1", "name": "Rab11 family-interacting protein 3", "aln": "--MELCQPTSLSDHDQPAS---GPQRGVMGLVGPDAPRGWSEEPE---------------EHAQLQRWPEGPNAPICWPEEVEEPHAPSRWAKEPNAPRCSSQEPDESCHLAEELEESDSPRCWPQEPDTPCHLAKELEEPDAPR-------CLPQEPDTPCYLAKELEEPNIPRCWPQEPDVPCHLAKELEEPDAPRCWPQEPDAFCHLLKEVEEPDALRCWLQGPDAPCHLAKELEDLDSPRCWPQE---PDESCHLAKELEEPDAPCHL-----------------AKELEEPDAPRCWPQEPDVPCLLAKKWEESDAPCLLTEELEEPDALHCWPQESEAPCLLAKELEEPDASHSCPQEADTGCLSAKEPEEPDVSHLWQGVPDAPCL-LVKEPEEADALHCCWPEESEEPDALNPPCFWANEPDEPDPSRCWSEEPQVLCLWPEEQNTKRCWQEEPDAPCFWPEDREEPIVSCLQFKEPEKPKVRSSWPE--ELEDCCPTRGLPLEPLLADGELLQACPGPPSDPGPALSLPSEPGTAQEEGARLRAVFDALDRDGD----GFVRIEDFIQFAT-VYGAEQVKDLTQYLDPSGLG-------VISFEDFYQGIVAIRNGDPDGQLYS-VEPVQ--DEETPACADEFDDFVTYEANEVTDSAYMGSESTYSECETFTDEDTS-------TLVHPELQPEGDVDSAGGSGVPSECLDTMEEPD---HGALLLLPGRSR-------------PHSQAVV---------MVIGSEE----HFEDYGEGNEAELSP--------------ETLCDGDG--EDPAFLTPSP-------------------------AKRLSSRKVARYLHQSGTLTMEALEDPPPEPVECPEEDIADKVIFLERRVSELEKDSAAAGEQHGRLRQENLQLVHRANALEEQLKEQEFRAQEKVLEETRKQKELLCKMEREKSIEIENLQARLQQLDEENSELRSCTPCLKANIERLEEEKQKMLDEIEELTQRLSEEQENKRKMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLRLEVEQRRGRSSSLGLQEYNSRARESELEQEVRRLKQDNRNLKEQNDELNGQIITLSIQGAKSLFSTSFSESLAAEISSVSRDE-------------LMEAIQKQEEINFRLQDYIDRIIVAILETNPSILEVK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7T005-1", "uniprot_id": "RFIP3_DANRE", "id": "Q7T005-1", "name": "Rab11 family-interacting protein 3", "aln": "MEQVLSSPQGCSEWEVNGKTEWESDQNPLGFLLVDKENSSVADPTNEIFQENAINLDDLFWASQTYSWENG--LDCVYPEWKAQPPPSQDLKGDGNSGISQLVEGDLICFNSRSASPSLADRPVQDNNLYDHAEQVEVTATSSTLNVCTGELGINAPTLHTDKTLLQDTHLMLEESHLTNCEFSCNSGVENESQNFLSHGTRN--ILESEGLFAVSPVEVSCVDTNSNPKPTIVCQTPPLASEHIYLSSSALPCEPVFPMTCTKPHVPPYHAGSATLPMDEVEMMLPKLQGGEGESSKPSANNRTLEPQRLDANTDTTHLSVCPLGESDISPEHCEEMLHELSTKCTVEMVEEEVNKKSVSSNTTNTAFSKPKTELCEELSGCTLGVLLETVSGDVKEEAASDSRTDHVFPETQTDLAPVALIDSQAEDPSTESLPRKNGQEESKSALPVSTPEHNALFELSSGNVVLPEDHSQSTFSAQTQALSEVDHDGDLTPDGMLTDNIVCEAVTSIDSVILSLTDSFELPKLSDCDLSSHDFESHALTLEIQNNVTCVQTGSVDNNPEEMSTPFTCTDNQLTVTGGLAGLDLTETTSQSGEASGEGEAGLPVLPTHQEDFHQLTPSEINLAQEQQVSSVVPSSPPSHRDVFPCGASLDGEAYLTLMENNPDTLKHAEMTLDLCKASDALPTKSLQIAPVDLIHVPIVSATAPRSEEQSALRAVFQALDQDGDGFVHIEEFIEFAKAYGAEQVKDLTRFLDPSGLGVISFEDFHRGISAISNEESAYSECETFTDEDTTALVHPELHEDVETDSGIENTLTDGDDRNSPSSFPASFQNFLQSEALEFFCTHCHKQISRLEDLSTRLQLLEMNRHLQQS--NNLDVMGDLTQDILDLADRDITDKVLLLEKRVCELEKDSLESEEQHARLRQENLTLVHRANALEEQLKEQELRTEEDLLAQTRKHRDALNKLQRERDLEIENLQARLHQLDEENSELRSCVPCLRANIERLEEEKRKLQDEADDITQRLNEESESRRKMSDKLSHERHTNQKEKECTQGLIEDLRKQLEHLQLFKLETEARRGRSSSNGLQEYNTHMRENELEQEIRRLKQDNRSLKEQNDELNGQIINLSIQGAKSLFTESLSESLAAEINNVSRAE-------------LMEAIHKQEEINFRLQDYIDRIIVAIMESNPSILEVK-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9ND89-1", "uniprot_id": "M9ND89_DROME", "id": "M9ND89-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSQPASQPDSIDLAYDMWAGQFEFVGPTNQQSNKNSNNN-------NNNSNLNNNKCRIGAQQNRKLS----------------TDSLEDLNLSFNTSASQNPLSNAYSLGVTGG--------AGSDYCGFGKHPPILIDQETFLSLNPADFEDIVPSNSEPN-------SLVFIENKLETNNNSLESNNNHINNNNNNKIYN------LENLTSKFN-----------------------------NKTNNTN-----TNGFKLENLKNFKN--------------KLLCDFEDTNSGGGGGGGSG--------------------------------------------GSGPVGMMNGALSAEICDNLNEQLELLQRKVDDLSDTQNIAEDRTTRTKTEYAVLQARYHMLEEQYRESELRAEERLAEEQKRHREILARVEREASLQNENCQMKIRATEIEATALREEAARLRVLCDKQANDLHRTEEQLELARDQIGVLQQEHEEQAQALR----RHEQEKKSTEELMLELGRELQRAREESGARAMPTTSPESIRLEELHQEL--EEMRQKNRTLEEQNEELQATMLTNQATMLTNGVEQGRHLLNGTLNS-LAQELEEMSQAQDSVDSATLASLSQLQQAFQEKEDENVRLKHYIDTILLNIVENYPQLLEVKPMERK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . : : . : : : :. : * : . : **: : . : . . . . . .: : : . .. *:. * . : : .: .. : : : . : : * : : . . : :: ::: :*:::* :*.. : :: * : * * * : **** :*.*:*: * : : ::::: * :::** .:: ** * ::: : * : **. .. *:. :: :: :: :: : ::. .:.:.. .: * :::*:.*: *: :* ::*:: : ..* *:* : . .*:.*: * *:::*..*: :. ::. .:: .: *:. ::.. ** *:..:*: : * :*::::*: *.**:.*** *:: *:*. *.:**** ", "identical_positions": 68, "similar_positions": 182, "identity": "5.63%" }, { "cls_id": "homologset.agr.MGI:2444450", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZU50-1", "uniprot_id": "D3ZU50_RAT", "id": "D3ZU50-1", "name": "", "aln": "MPHPIWLQHRVYAGASGSTERAPQPRPLPGSLWSCGRAGLEHPCAGRLGDCEAASPAASSGEDMSNDDE----AAAEAAG-DTHLLGFSDEILLHILSHVPSTDLVLNVRRTCRKLAALCLDKSLVHTVLLQKDYQASEEKVKQLVKEIGREIQQLNMAGCYWLPGSTIEHVARCHSLVKVNLSGCHLTSLRLSRVLSCLQRLRSLAIDVSPGFDASQLSSECKATLSRVQELKQTLFTPSYGVVPCCASLQKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPG-SFAESGATKNLLDSMARNV--ALDALQLPKSWLNGSTLLQHMKFNNPFYFSFSRCTLSGGHLIQRLINGGKDLRSLASLNLSGCVHCLSADSLLRKAEDDIDSSILETLVESCCNLHHLNLSAAHHHS--SDGLGRHLCQLLARLCHLRSLSLPVCSVADSAP---RPDRAPAPPAMHAVPRGFGKKVRIGVQTCPNP---FVGQSAPQPAS--VFWSLLKKLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQNVGDSEVAAIGQLTFLRHLTLAQLPGMLTGSGLVSIGLQCQQLQSLSLANLGMMGKVVYMPALADMLKHCKRLKDLRLEQPYFNANAQFFQALGQCSSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHMFTGESLTTCKSLQQSLLRSFQAERPALNVVIFPLLHEGLTDVIRDVPMVHLDEITLFKSRVAEEPPNLWW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AEK2-1", "uniprot_id": "A0A8I6AEK2_RAT", "id": "A0A8I6AEK2-1", "name": "", "aln": "---------------------------------------------------------------MSNDDE----AAAEAAG-DTHLLGFSDEILLHILSHVPSTDLVLNVRRTCRKLAALCLDKSLVHTVLLQKDYQASEEKVKQLVKEIGREIQQLNMAGCYWLPGSTIEHVARCHSLVKVNSSGCHLTSLRLSRVLSCLQRLRSLAIDVSPGFDASQLSSECKATLSRVQELKQTLFTPSYGVVPCCASLQKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPG-SFAESGATKNLLDSMARNV--ALDALQLPKSWLNGSTLLQHMKFNNPFYFSFSRCTLSGGHLIQRLINGGKDLRSLASLNLSGCVHCLSADSLLRKAEDDIDSSILETLVESCCNLHHLNLSAAHHHS--SDGLGRHLCQLLARLCHLRSLSLPVCSVADSAP---RPDRAPAPPAMHAVPRGFGKKVRIGVQTCPNP---FVGQSAPQPAS--VFWSLLKKLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQNVGDSEVAAIGQLTFLRHLTLAQLPGMLTGSGLVSIGLQCQQLQSLSLANLGMMGKVVYMPALADMLKHCKRLKDLRLEQPYFNANAQFFQALGQCSSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHMFTGESLTTCKSLQQSLLRSFQAERPALNVVIFPLLHEGLTDVIRDVPMVHLDEITLFKSRVAEEPPNLWW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F8VQK6-1", "uniprot_id": "F8VQK6_MOUSE", "id": "F8VQK6-1", "name": "", "aln": "---------------------------------------------------------------MSSEEE----AAAEAAG-DTHLLGFSDEILLHILSHVPSTDLVLSVRRTCRKLAALCLDKSLVHTVLLQKDYQASEEKVKQLVKEIGREIQQLNMAGCYWLSGSTIEHVARCHSLVKVNLSGCHLTSLRLSKVLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVQELKQTLFTPSYGVVPCCASLQKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPG-SFAESGATKNLLDSMARNV--ALDALQLPKSWLNGSTLLQHMKFNNPFYFSFSRCTLSGGHLIQRLINGGKDLRSLASLNLSGCVHCLSADSLLRKAEDDIDSSILETLVESCCNLHHLNLSAAHHHS--SDGLGRHLCQLLARLCHLRSLSLPVCSVADSAP---RPDRAPAPPAMHAVPRGFGKKVRIGVQTCPNP---FVGQSAPQPAS--VFWSLLKKLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQNVGDSEVAAIGQLTFLRHLTLAQLPGMLTGSGLVSIGLQCQHLQSLSLANLGMMGKVVYMPALADMLKHCKRLKDLRLEQPYFNANAQFFQALGQCSSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHMFTGESLTTCKSLQQSLLRSFQAERPALNVVIFPLLHEGLTDVIRDVPMLHLDEITLFKSRVAEEPPNLWW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96ME1-4", "uniprot_id": "FXL18_HUMAN", "id": "Q96ME1-4", "name": "F-box/LRR-repeat protein 18", "aln": "--------------------------------------------------------MASSGEDISNDDDDMHPAAAGMAD-GVHLLGFSDEILLHILSHVPSTDLILNVRRTCRKLAALCLDKSLIHTVLLQKDYQASEDKVRQLVKEIGREIQQLSMAGCYWLPGSTVEHVARCRSLVKVNLSGCHLTSLRLSKMLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLFTPSYGVVPCCTSLEKLLLYFEILDRTREGAILSGQLMVGQSNVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPQNLHAFLISVPG-SFAESGATKNLLDSMARNV--VLDALQLPKSWLNGSSLLQHMKFNNPFYFSFSRCTLSGGHLIQQVINGGKDLRSLASLNLSGCVHCLSPDSLLRKAEDDIDSSILETLVASCCNLRHLNLSAAHHHS--SEGLGRHLCQLLARLRHLRSLSLPVCSVADSAP---RADRAPAQPAMHAVPRGFGKKVRVGVQSCPSP---FSGQACPQPSS--VFWSLLKNLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDSEVAAIGQLAFLRHLTLAQLPSVLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVYMPALSDMLKHCKRLRDLRLEQPYFSANAQFFQALSQCPSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHLFTGESLATCKSLQQSLLRSFQAERPALNVVIFPLLHEGLTDVIRDVPLVHLDEITLFKSRVAEEPPNLWW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1N7G6-1", "uniprot_id": "A0A8M1N7G6_DANRE", "id": "A0A8M1N7G6-1", "name": "", "aln": "---------------------------------------------------------------MNNQIETAQCFSDNISQVSVTISDFSDEILLNILRFIPSHDLILNVSRVCRKLRTLCLDKSLRVHVHLHKEYTANDDAVKQLLKVISADIQTLNLNGCYWLAGSTVDQVTRCKSLVSLDLSGCRLTSVRLSHLLSSLSSLKSLALDVGPGFDLHQLSAEGKSALARLQELKQTLLTPSYGVVPCCSALRRLHLYLEASEVWREAGG-CAQLMVGQSSVPHYQNLRWFSARLAPGEVNRTLLALYLAVFSMRVPEGLAGLVLSVPGPAPPRPVAMTALMESMASTVGNTVSALQLPRTWLDGAILGRVLAHGCPAYLNVSRCSSPGFNPLHVLLSAGRDLTPLRSLNLRGCGRGPLSESCG-KGDEEMDTDSVKALAECCPHLNHLNLSATHYHHNLSTGQDGHLCGTLGRLTGLCSLALPVCALAQSPPTQINNQDSNTDLASRSLLLGLKKTTRIGVPTYRPTSEIAVGQGEERTDRGLCIQPLLQGCPYLVELELIGAGFSSAMPRNEPAIRKDPAACSWSYSVGDGELAALGGMKFLRKLTLAHLPGVLKGTGLIELLQGCKDLHSLSLANLGSLKTMNYTQALLEALSYCTQVRDLRLEQPYFNANAAFFEALSQCGQLRRLCLVSRHGTFQPAAVTAFMQSCSDVIMCHMFMGGTLVACKTLQKTLLDSFSVSRPALSVVIYPLLHEDLAHVIRGMPLCHLDEMTLFKSRVAEEPMSR--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..: : : : .. : .*******:** .:** **:*.* *.**** :******* * *:*:* *.:: *:**:* *. :** *.: *****.***:::*:**:***.:: ***:***:***::**.*. *:***:**.**** ***:* *::*:*::******:**********::*.:* **:* : **.. ..*******.******** * ****** :*: :: *****:* *.*:.* .:::**** : ... * . *::*** .* .:.*****::**:*: * : : .. * *:..***: .* : :: ::..*:** .* **** ** : .:* *.::::*:. :::*. .* :*.******:*:* * * . *** *.** * **:****::*:*.* . : : : * ::: *: *..*:** : . **. :. : .**: *:* .*****:.*************:. ..** : .***.*:**:* : ***:****:**.:*.*:**:.: *:.*:******** : .: * ** : *.:*.:::*********.*** **:**.** .*:******* **:** ** *** * :*:***:* * :*.:**:**::** **...****.***:*****.*:.***.:*: ****:*********** . ", "identical_positions": 355, "similar_positions": 219, "identity": "45.05%" }, { "cls_id": "homologset.agr.MGI:2444451", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3V4-1", "uniprot_id": "D4A3V4_RAT", "id": "D4A3V4-1", "name": "", "aln": "MSASEVAGLGARAPSPSESSASCTSKSDDALPDGLSPKDSAQKQKNLSPPSVSSQMITEESNRNARLEHPEQNPGPSVGDTSAAHQEVLGENLVATALCLSGSGSQSDLKDLTNPAGEEGDTSLRESLHPVTRSLKAGCHSKQLASRNCSEEKCPAASILKEGSRDTGLDFRPVVPPANGVEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVESQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSLPQIPTPTLPPPPSEADFMLQVFQPSPSLTPRMPFSIGQVTMPMVMPSADPRSLSFPILNPALSQSNQPSPPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGIKASTETPRPQPVDKLEKILEKLLTRFPQCNKAQMTNILQQIKTARTTMAGLTMEELIQLVAARLAEHERVASSTQPLGRIRALYPAPLAQISTPMFLPSAQVSYPGRSSHAPPTCKLCLMCQKLVQPSELHPMACTHALHKECIKFWAQTNTNDTCPFCPTLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFU3-1", "uniprot_id": "RN214_MOUSE", "id": "Q8BFU3-1", "name": "RING finger protein 214", "aln": "MAASEVAGLGAGTPSPSESSALCASKSDESLPDGLSPKDSAQKQKNLSPPSVSSQMITKESNRNAHLEHPEQNPGSSVGDTSAAHEEVVGENLVATALCLSGNGSQSDLKDLTNPAGEEGDTSLRESLHPVTRSLKAGCHSKQLASGNCSEEKCPAASVLKEGSRDAGLDLLPVVPPANGVEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVESQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSLPQIPTPTLPPPPSEADFMLQVFQPSPSLTPRMPFSIGQVTMPMVMPSADPRSLSFPILNPALSQSSQPSPPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGIKASSETPRPQPVDKLEKILEKLLTRFPQCNKAQMTNILQQIKTARTTMAGLTMEELIQLVAARLAEHERVASSTQ-----------------------------------APPTCKLCLMCQKLVQPSELHPMACTHALHKECIKFWAQTNTNDTCPFCPTLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8ND24-1", "uniprot_id": "RN214_HUMAN", "id": "Q8ND24-1", "name": "RING finger protein 214", "aln": "MAASEVAGVVANAPSPPESSSLCASKSDEGLPDGLSTKDSAQKQKNSPLLSVSSQTITKENNRNVHLEHSEQNPGSSAGDTSAAHQVVLGENLIATALCLSGSGSQSDLKDVASTAGEEGDTSLRESLHPVTRSLKAGCHTKQLASRNCSEEKSPQTSILKEGNRDTSLDFRPVVSPANGVEGVRVDQDDDQDSSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEFLQKEQDLKAEIEKLCEKGRREVWEMELDRLKNQDGEINRNIMEETERAWKAEILSLESRKELLVLKLEEAEKEAELHLTYLKSTPPTLETVRSKQEWETRLNGVRIMKKNVRDQFNSHIQLVRNGAKLSSLPQIPTPTLPPPPSETDFMLQVFQPSPSLAPRMPFSIGQVTMPMVMPSADPRSLSFPILNPALSQPSQPSSPLPGSHGRNSPGLGSLVSPHGPHMPPAASIPPPPGLGGVKASAETPRPQPVDKLEKILEKLLTRFPQCNKAQMTNILQQIKTARTTMAGLTMEELIQLVAARLAEHERVAASTQPLGRIRALFPAPLAQISTPMFLPSAQVSYPGRSSHAPATCKLCLMCQKLVQPSELHPMACTHVLHKECIKFWAQTNTNDTCPFCPTLK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:******: * :***.***: *:****:.******.********* . ***** **:*.***.:***.*****.*.*******: *:****:********.********::..*************************:***** ******.* :*:****.**:.**: ***.***************************************************************************.*************************************************************************************************************************************************************************************************:*************:***********************************..***.**************************************:***:*******************************************************************:*** **.************************.*************************", "identical_positions": 612, "similar_positions": 45, "identity": "87.06%" }, { "cls_id": "homologset.agr.MGI:2444453", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R3X3-1", "uniprot_id": "M0R3X3_RAT", "id": "M0R3X3-1", "name": "Rho guanine nucleotide exchange factor 10", "aln": "------------------------------------------------------------MDQGEASPPVPAEHEVKCDTSN-------NEEE-GELFDFESGDEVPE--------------------------------------------------ADRQAPTADDGTGVAEADGADENTSPDGTGVAEADGADENTSPDGTRVDEADGADEN-----TSPAG--NGTGAESVPEAEPEKLVVPIKVNPYSVIDITPFQEDQP------PSPDANPEEEGVGLRVP------SGYCVPVPCGYAVPSNLPLLLPTYSSQIIIR----------------------AQSVEEE-VAAEVAGDGQCNSLSSEDLPHSGDQGSQEGSALARWAADPANTAWMENPEE--------------------AIYDDVPRENSDS----------------------------------EPDEMIYDDVENGGEGGNSSLEYG---------WSSSEFESYEEPSDSE---GKNGIPRSFLR----------------------------------------------------------SNHKKQLSHDLTRFKAHCEEKMR-----------------------GLVASTVGAMEAQ---QRQEWKMQRLMKAAKEGTRDG---------------------------LEKTKAAVKRGRSFIRTKSLVSQDHRYYFEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQNLFIDVDCKH-----------PEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLRMVFYRIKEILQCHSMFQIALASRVSEWDAVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEIKQIAKAINERYLNKLLSSG------------NRYLVRSDDVIETVYNDRGEIVKTKQRRIFMLNDVLMCATASSRNSHESHAMMN--------QRYLLKWSVPLGQVDVIEYSGSSGTG-------------------------DHSRHHTAHSPESLAVVANVKPH-----KVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLNQSVAHDWTSGLQQLILRKEDAIRAADRCRIQLQLPGKQDKSGRPTFFTAVFNTFTPAIKESWVSSLQMAKLALEEENHMGWFCVDDDGSLAKKETHPLLVGHTSVMVAK----QPEFKIECAAYNPEP---------YPSNDNQPASPSTARGFLWIGSCSNQMGQVAIVSFQSANPKVIECFNVESRILCMIYIPAEESKPQEPADTKDPEATASRAPHVP-----------------TICLGTEEGSISIYKSSQGCKKVRLQHFYTPDKSTVMSLACSPHGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLG--VLPVRSLLLVEGALWAASGGQVFMASVETHTVENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQR------LSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVTATAFQ--------------------------------------------------------NKDRARDRPRSSSELQDEDPKDLLCGEEGTSCLGQTDTSTAVWLGDSLGLTAQ-NDLSSSSG--SLSHGSSSLEHRSVDS------------------------------------SLCDLLRDPS---------------------------AFPRSRAQSSRRARASSALVVCGGQ--------GHRRVHRKARQPSQEDLVSSVMVWQIPLLGM-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C033-1", "uniprot_id": "ARHGA_MOUSE", "id": "Q8C033-1", "name": "Rho guanine nucleotide exchange factor 10", "aln": "------------------------------------------------------------MEQGEASPPVPAEHEAKCDTSN-------NEEE-GELFDFDSGDEVPE--------------------------------------------------ADRQVPSADDRTRGAEAG----------------------------------GADEN-----TCPAG--NGTGAEPAPEAEPAKLVVPTKVNPYSVIDITPLQEDQP------SSPDANTEEEGVGLRVP------SGYSVPVPCGYAVPSNLPLLLPAYSSPVIIR----------------------AESVEEE-EAAETVGDGQCNSLSSEDLPHSSEQGSQEGSALARWAADPANTAWMENPEE--------------------AIYDDVPRENSDS----------------------------------EPDEMIYDDVENGEEGGNSSPEYG---------WSSSEFESYEEPSDSE---GKNGIPRSFLR----------------------------------------------------------SSHKKQLSHDLTRFKAHCEEKMR-----------------------GLVASTVGAMEIQQAKQRQERKMQKLMKAAKEGTKDG---------------------------LEKTKAAVKRGGSFIRTRSLVSQDHRCYFEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQNLFIDVDCKH-----------PEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLRMVFYRVKEILQCHSMFQIALASRVSEWDVVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEIKQIAKAINERYLNKLLSSG------------NRYLVRSDDVIETVYNDRGEIVKTKQRRIFMLNDVLMCATASSRNSHESHAVMS--------QRYLLKWSVPLGHVDVIQYNGGSGAG-------------------------EHCRHHAAHSPESLAVVANAKPH-----KVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLNQSVAHDWTSGLQRLILRKEDAIRAADRCRIQLQLPGKQDKSGRPTFFTAVFNTLTPAIKESWVSSLQMAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVAK----QPEFKIECAAYNPEP---------YLSNESQPASPSTARGFLWIGSCSNQMGQVAIVSFQGSNPKVIECFNVESRILCMVYIPAEESKPQETTETKDPEATASRAPHVP-----------------TICLGTEEGSISIYKSSQGCKKVRLQHFYAPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLG--VLPVRSLLLVEGALWAASGGQVFMASVETHTIENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQR------LSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVSATAFQ--------------------------------------------------------NKDRARDSPRSGSELQDEDPKDLLCSEEGPSCPGQPDTYTSVWLGDSLGLPTQKNDLSSSSGSLNLSHGSSSLEHRSVDS------------------------------------SLCDLLRDPS---------------------------ASPRSRPQGSRRARASSALVVCGGQ--------GHRRVHRKARQPSQEDLVSSVMVWQIPLLGM-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15013-1", "uniprot_id": "ARHGA_HUMAN", "id": "O15013-1", "name": "Rho guanine nucleotide exchange factor 10", "aln": "------------------------------------MRPPGFLSRAPSLNRAERGIWSCSMDQREPLPPAPAENEMKYDTNN-------NEEEEGEQFDFDSGDEIPE--------------------------------------------------ADRQAPSAPETGG--------------------------------------AGASEA-----PAPTGGEDGAGAETTPVAEPTKLVLPMKVNPYSVIDITPFQEDQP------PTPVPSAEEENVGLHVP------CGYLVPVPCGYAVPSNLPLLLPAYSSPVIIC----------------------ATSLDEEAETPEVTEDRQPNSLSSEEPPTSEDQVGREDSALARWAADPANTAWMENPEE--------------------AIYDDVPRENSDS----------------------------------EPDEMIYDDVENGDEGGNSSLEYG---------WSSSEFESYEEQSDSE---CKNGIPRSFLR----------------------------------------------------------SNHKKQLSHDLTRLKEHYEKKMR-----------------------DLMASTVGVVEIQQLRQKHELKMQKLVKAAKDGTKDG---------------------------LERTRAAVKRGRSFIRTKSLIAQDHRSSLEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQNLFIDVDCKH-----------PEAILTPMPEGLSQQQVVRRYILGSVVDSEKNYVDALKRILEQYEKPLSEMEPKVLSERKLKTVFYRVKEILQCHSLFQIALASRVSEWDSVEMIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPAFLEFLKQEQEASPDRTTLYSLMMKPIQRFPQFILLLQDMLKNTSKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLSSG------------SRYLIRSDDMIETVYNDRGEIVKTKERRVFMLNDVLMCATVSSRPSHDSRVMSS--------QRYLLKWSVPLGHVDAIEYGSSAGTG-------------------------EHSRHLAVHPPESLAVVANAKPN-----KVYMGPGQLYQDLQNLLHDLNVIGQITQLIGNLKGNYQNLNQSVAHDWTSGLQRLILKKEDEIRAADCCRIQLQLPGKQDKSGRPTFFTAVFNTFTPAIKESWVNSLQMAKLALEEENHMGWFCVEDDGNHIKKEKHPLLVGHMPVMVAK----QQEFKIECAAYNPEP---------YLNNESQPDSFSTAHGFLWIGSCTHQMGQIAIVSFQNSTPKVIECFNVESRILCMLYVPVEE-KRREPGAPPDPETPAVRASDVP-----------------TICVGTEEGSISIYKSSQGSKKVRLQHFFTPEKSTVMSLACTSQSLYAGLVNGAVASYARAPDGSWDSEPQKVIKLG--VLPVRSLLMMEDTLWAASGGQVFIISVETHAVEGQLEAHQEEGMVISHMAVSGVGIWIAFTSGSTLRLFHTETLKHLQDINIATPVHNMLPGHQR------LSVTSLLVCHGLLMVGTSLGVLVALPVPRLQGIPKVTGRGMVSYHAHNSPVKFIVLATALHE------------------------------------------------------KDKDKSRDSLAPGPEPQDEDQKDALPSGGAGSSLSQGDPDAAIWLGDSLGSMTQKSDLSSSSGSLSLSHGSSSLEHRSEDS------------------------------------TIYDLLKDP----------------------------VSLRSKARRAKKAKASSALVVCGGQ--------GHRRVHRKARQPHQEELAPTVMVWQIPLLNI-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJ04-1", "uniprot_id": "A0A8M3AJ04_DANRE", "id": "A0A8M3AJ04-1", "name": "Rho guanine nucleotide exchange factor 10", "aln": "--------------------------MFSMDVEDFPPPPPDLLDDEDEGERFEFDDSGDEAPEADRPPPEPEGISVPPPCSSSVRDAPVNEASPNPEHTFNAEADLPP--------------------------------------------------PPQDFPANNRPLAEALFKQSDLPPLPPP-----------------PPTELCPGAAEGRKIDLNPPAEGTDVHRMQDENKGASVVCSSKPKVSPYSVIDIGPIQQQLPSEQSGPPSSPSANQIEGVVQEVSGSPGLSSGYSVPVPCGYATPSNVPVIPPTYTTPVLIR----------------------HFSMDED-VTVVGAVNTPVDSVFSEECPVIKEE-----DALTKWVSDPANTAWMESPDE--------------------VIYDDVPRENSGST--------------------------------TDPDEMIYDDVEFGEEGGSSSLDNG---------WSSSEFESYEENSDVENGHGENGLPDAFVRGRA-------------------------------------------------------PSKKTHLSEDLARLKEHYERKMR-----------------------DLMANTVGTVELQQLKHKHEQKMQRLVKAAKDGTKDG---------------------------LQKTKAAVRKGRSFIRTRSLCHEKKPSCFDE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESDLFIEVECFN-----------VDPVLGPAPDGLTQHQVMRRCILEKILESEKSYLEALKRILEQYEKPLAEIEPRLLSDRKRKVVFHRIREILQCHALFQMALASRVSDWDELEMIGDVFVASFSKSMVLDAYSEYVNNFSLAMGVVRKACAAKPCFLDFLKHRQETSKDRLTLYGLMMKPIQRFPQFILLLQDMLKNTPVGHADRLPLQMALTELEVLAEKLNERKKEADQRCEIRHIAKAMNEHYLNKLLSSG------------SRYLIRSDDMVETVYNDRGEIIKTKERRVFLLNDVLMCATPNRRPSQDGVSVGAGGEGVPSGQRFLLKWSVPLSFVEVVEFG-SSEEM-------------------------VDSRFPPSHSGD--KVVINAKPN-----KLYMGPGQLYQDLQNLIHDLGLVNQISTMISSLKGNYQNVNGTVAQDWVSGLQRLILKKEEEIRAADRCRIQLQLPGKQDKYGRPTFFTAVFNTFSPSIKQTWISNLQMAKLALQEDNIQGWFCAEDDGNQMRKQNHPLLLKQMAVVMSK----LQEFKVECAVHNPEP---------HVNTDSTADLPVMGHGCVWVASCTNHMGQVSIVALQNSNPKVTECFNVESRILCMTHVPLDEPLKNVEGKPEN-----RNACDMP-----------------TVCLGMEEGSISVYKSSQRSKKVRLQHFFSPDKSSVTCLVYTSGCLYAGLVSGSLVIYSRTDDGFWVESGACVLKLG--VLPVKALLVVGEHIWASSGGQIFIISTQTNTVERQFEAHQEEGMIVSHMVVAGVGIWISFSTGSTLRLFHTETLDHLQDINIATAVNNILPGQQR------VSVSSLLVCHGLLLVGTNLGVTVALSVPRLQGIPKVTGRGMVSFHAHHGPVKFLTMATAVC--------------------------------------------------------NVSQATMATLTSSTPSQCQP-EASELEGATLNQNCSRGSHAPVLQDSP---------SSSCGSLALSQAS--LEHGPEDG------------------------------------AIYDLLNEP-----------------------------AHFQKAKQTDRVSASSVLVVSGGL--------GHRRINRKTKQSKHEEMASTIMVWQIPLPSL-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PHU0-1", "uniprot_id": "M9PHU0_DROME", "id": "M9PHU0-1", "name": "DH domain-containing protein", "aln": "MESLGLGSRRNNGSNSTAAPTTGQGGVVGGGGVAGKVLVHTKLKQQQQQQHSNQNYYTQQQTQLQRLKQQQQKLQQQQQQQQQQQLEAVHGGVAKQCLQFPPPPDYPPPITGGGGSPVNTTPGRRQQLPRYPDPDPDAIEICNESATLETSPYHLKQLAARHSKTLGRNLGHQPHHHHTVHLHHDYSYAYYEPGAAMRHSNVPGAVSSGGGGGGGGAGRVSSVVDTSSSSSPTAEPPPNSIRALLSKGKKNKQLVSPATLQSYQTRYHKLTTKSGMGQSENFYEEINAAALQTSSGHHLRSTVGSHSAGSLNQTLVEEELRRVQNRHHKILGELNLSVEAMLMPESPPKSIDQQPLGSGSGGSGGAEATPPQPSVSVTAASGQPPTILARLTSASADNICDSGGEAGKRTKTAPGCPGGGVEQLLTTTCGDLDSGFSGSSGASYIGSLRLSKTQHIKCARQTPTVGTQSCRSFQRAATVYDEAGMSGGGGQSGSSFLTRASCGRRILSCARIRAAEDPGPNHRIAGGNGIQTVQTTATESKARSFWSRKGWRKLPGFSTSTSSINDTGLSDEHKLNSGSWEDTLDEPHHHHAHHSHHQQHLHQHHSHLSQRHQQQQQQQQQLQQTSFIGSPPSSASITTAQLHSAFSRRIAEQRERDQRDQRDQREAVGCTAATIAGGSFSANGGQAAVGVGVGSSSSCGSSSERDTKSPCRERDRNLERDRDRERDKNDDLGEEEVLTEEEQTSSSVSSLSAGNQRNSQLRSTFNKAKQHLSFDKWRTAATGSATGSASGPGSSATDSNNAASNMIMRRASACTMPSSGGGGGAGVGSSQREEATTPGESPGGRLSRWFSIRRGSSHQYDVGGRDGRHSTASSFDTPDSGSGNSPKNGSNAVAGTGGAGSQGVALDAASPQKLANLGASKMMPGVPESEDDEATANRFDVDLMMTPGSRANGTARTAHNRLIVPMLPPAPAGLSQQQLKRRHIVAAIVHSENSYVATLQRLVNDYKKPLEECSPPVLNPVKIATLFHCLPDILHSHKLFRISLAECVRNWDRDEKIGDCFVSAFGKPQLLEIYSGFINNFSAAMELAKMEEKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFILFLQDLLKYTPQGHHDRMSLQLALSQLELLAELLNESKREAEQYQAFKEMLGHISGTFNARSLSLSSVSVSDSAGGHRPRYLLREDNVTHMEFNQAGFIVKCKQRRLLLLNDKVICVSVAPKQSHDFGATEK----------LTFKWMFPVNDVEIVDNSTSATLSRILTAGLNRGGSLKSNGSSGANGSPYANSTLPGHGGGVSGFSGFGDPHSSPAAQLTNGADNLCSEMSTLMYDYEVISRIQDLVSSLKGSYKELNANTTRNVLNLIQGSIQRKDEEMAWVDSCCLQLIGRHKSGKEE-----TFTFQTQTPAVKKEWITELRLAQLALDPNNSPAWERGGSHPQPAHHHPHHHPLQHPHAGAGDPRQTQEQLQLQEAVQQKQSRKMPLFVKAMPVYKSQHQTEVRCGCYYSIANDTKQSGNARRRHKQLNYLWMCSSDGTSSHITVLAQHPQQAGNLREAGAFDLFETQVSALEFVKGLDQLKSRDEPASLLGDLVWLGTDSRKILIYSARNPEQEEQLGSYSVPG--AVQRILYHFDAVYVALSGATVLIFRRGNDGVWQLRDPQTIRLGDTDLVVPSLLPINMCIYASCGNRVYVMNALNGEIQRSFEVQHGATQQVNLMAHSGIGLWISLKNSTMLCLYHTETFKHLQDINIASSVLRHDGKKEQPLNNSSVYVTALMACKGLLWVGTNVGIAVTIPLPRLEGVPIISGGINMSCHAHFGPITFLLPLIPKVYPAYKPPTVGAAPLVPSMGDDLQLPAIDADPKIQELDDGAVVLRRDLAKEEMSSSNPGADSTASSPRSSKLDKQNSLDQSFTAKIRASLANSPAFHRKRFRDDPNRMSKTLPRGLGAAAAGSGAGGASAAGSGTASGNTSQHGEHGICDVYGLYGKLIFVKEDYDAEEGNQGNLMDMMYEGMRRSDPELAAIPGKVCTLDRRLRMKASRPRSLDLSNWSVDSKSSSLYTSSGSEESMGIRHFGGRSVSRNSSSASHKTSGTGSDLGNISENGLMTTADIHHHQQQQQQLNSSAKPDEMSRLGAGNSGLDKPAAAVATLKRKQKQNSKQQQQQNADGPRTVITLMGGRGYWRQMWYNGAGGSPSHKNSSSGGGGGSGSGFSGQTMQSGNPSCSPLTANSNDAHIVVWEKKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .. : * . : * . :. : *. . . . . .::. .:*. . ... . : . .*: : . * ...: : *:::: . :: .: *:: .: .*:. .. : . .*: *.* : :**:. . **.*. . *.:.:.: *: . . **: . :: :* .. :::. : :.: : * : : * .::: : *: ... .* * : . .. .:. .: * :. :.: :* : :*:: . .:* * * **:*:*: ** *: ::.**:.*: :*:*::::*:*** * .* :*. * :*: : :**:.* :*:::**. * :** * *** **::*.*. :*: ** ::**** *: : : *..: :*:* * :: ** ::..**::*:********:***:** *. ** **:.**:**::** *** *** *::*:* .:.: :. : : ** . ***:*.*:: . :*: * *:* *:**:::*** ::*.: : *:: :** .*:. *: :: . .: . * . .*: :: *..:* .::..*::* ::.:* ::..*:*.*:::* ..::: . :* * :*:: : .* * :** *..* * .*:* :*::*: *:..*::*:***: :* .* .. . ::. * : : . .. ::::: *. : :. .. :.. ::: *: * : .. ...*:* : * : . : : :* :. .* :*.: : :: :* : * :* : :*..* ..:: : : ** * .::** * * :** : ::*:.*.:::: .. . :: .:*.:: :. *. :*:*:**::...: * *:****:.****:** :.* ::: : *::*:.*:*** ***.:*: *::.:***:*:* ::* :* *** .*:.*: . : .. .. : : : *. . ... . .. . : *:: : . .. : :** . .*. * * : *:: .. :: . : :*. .: ", "identical_positions": 254, "similar_positions": 469, "identity": "11.14%" }, { "cls_id": "homologset.agr.MGI:2444461", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABZ3NNL2-1", "uniprot_id": "A0ABZ3NNL2_RAT", "id": "A0ABZ3NNL2-1", "name": "Post-GPI attachment to proteins factor 3", "aln": "MLPECLFCFCTCGDRILREGVSGGCNDEHRYFRLLRKWDFVLFQAPPSAAGQSDRMARRTAPLLLLTLAVGLAGSSQGDREPVYRDCVLRCEE-RNCSGDALKHFRS------------RQPIYMSLAGWTCRDDCKYECMWLTVGLYLQEGYRVPQFHGKWPFSRFLFIQEPASALASLLNGLASLVMLCRYRASVP---------ASSPMYHTCMAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASAVILHSVYLCCVRTVGLQHPTVASAFGALLLLLLTGHISYLSLVHFDYGYNMMANVAIGLVNLAWWLVWCLRNHRRLPHTRRC----------------------MVVVVLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHTLFFRFLEDDSLYLLKESEAMFKLD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A559-1", "uniprot_id": "PGAP3_MOUSE", "id": "A2A559-1", "name": "GPI-specific phospholipase A2-like PGAP3", "aln": "-------------------------------------------------------MAKRTAPLLLLTLAVGLAGGSQGDREPVYRDCVLRCEE-RNCSGDALKHFRS------------RQPIYMSLAGWTCRDDCKYECMWFTVGLYLQEGHRVPQFHGKWPFSRFLFIQEPASAVASLLNGLASLVMLCRYRASVP---------ASSPMYHTCMAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASAVILHSVYLCCVRTVGLQHPSVASAFGALLLLLLTGHISYLSLVHFDYGYNMMANVAIGLVNLAWWLVWCLRNRQRLPHTRRC----------------------MVVVVLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHTLFFRFLEDDSLYLLKESGAMFKLD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96FM1-1", "uniprot_id": "PGAP3_HUMAN", "id": "Q96FM1-1", "name": "GPI-specific phospholipase A2-like PGAP3", "aln": "-------------------------------------------------------MAGLAARLVLLAGAAALASGSQGDREPVYRDCVLQCEE-QNCSGGALNHFRS------------RQPIYMSLAGWTCRDDCKYECMWVTVGLYLQEGHKVPQFHGKWPFSRFLFFQEPASAVASFLNGLASLVMLCRYRTFVP---------ASSPMYHTCVAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASTVILHSIYLCCVRTVGLQHPAVVSAFRALLLLMLTVHVSYLSLIRFDYGYNLVANVAIGLVNVVWWLAWCLWNQRRLPHVRKC----------------------VVVVLLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHVLFFSFLEDDSLYLLKESEDKFKLD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WFS8-1", "uniprot_id": "PGAP3_DANRE", "id": "A8WFS8-1", "name": "GPI-specific phospholipase A2-like PGAP3", "aln": "-------------------------------------------------------MFLAAAAFLLS----APASASQGDKEPVYRDCVKHCVR-ANCTGARLRGFQS------------TQPPYMALTGWTCRDDCRYQCMWTTVGLYQAEGYSIPQFHGKWPFARFLCFEEPASALASLLNGLACLLMLLRYRSAVP---------CQSPMYHTITAFSLVSLNAWFWSTVFHTRDTYLTEKMDYFCASAVILYSIYLCCVRTLGLRRPAISSMVGVLLILAFTSHVSYLTFVSFDYGYNMAANASIGIINLLWWLCWCWLNRRILPYWWRC----------------------GMVVLLLHGLALLELLDFPPLFWVLDAHAVWHLSTVPVHFLFYSFLIDDSLHLLNTEKPGVKLD-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K0P4-1", "uniprot_id": "PGAP3_DROME", "id": "Q7K0P4-1", "name": "Post-GPI attachment to proteins factor 3", "aln": "-----------------------------------------------------MSSRSLSAIVLLLGALVTACLASNGDRTQFFHNCRQNCER-TNCSADGLEIQEQAV-------KFYQQSVFDRLFQWSCADECQYGCMWRTVFAFFERGWPIPQFYGKWPFLRLLGMQEPASVIFSCLNFVVHLRLLRKFRREVR---------PDSPCYMLTHIFAVTSLNGWIWSAIFHTRDFPLTELLDYAFAYSIILCSLYVMVMRMLHRYSLFLRGVITLAFLSYYINYFAYLSVGRFNYAFNMMVNVATGVIAAVGWFVWCHFVRTRRPYFRRI----------------------LRFYILMALAMSLELLDFPPILWILDAHALWHLATIPLASLYYECV--EILLYSNIATCVCILAS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P25625-1", "uniprot_id": "PER1_YEAST", "id": "P25625-1", "name": "Protein PER1", "aln": "---------------------------------------------------------MRLAVVVTLLVHCFLVTCSPGDNLDEFIDCTYACEYNRRCPNSQINYIDPETNMFHDIEFFDTPPLYSKLLFWDCISDCDYQCQHIITRWRIDEEEEIYQFHGKWPFLRVLGTQEFFSTIFSIGNFIPHYKGFVKFSRIIREEGDRRRKNSRSILIWNYLYVTVAGMLAWTASSVFHCRDLIITEKLDYFFAGLTVLTGFHAIFARMTSMFLYPKIAQAFTASVAAIFALHILRLYVDWSYTYNMRFNIFFGVLQYILLIMLSCQNYHALQKQKLMGEFKKTAYSSFKRQIFKLCVIPILLVIVTTMAMSLELFDFFSYEWQIDAHALWHLCTIWPSWVLYDFFLEDYAYWGNRQLY------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: * **. : :* * .*. :. . : * * * .:* * * . . : **:***** *.* :* *.: * * : : :: : * .: ..: .* *::** ** :** :** * :* ..: * . : :.* :*: * *:: : . . :: ***:** . * :****:**:.*: : : . : : ", "identical_positions": 57, "similar_positions": 65, "identity": "13.57%" }, { "cls_id": "homologset.agr.MGI:2444462", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5VW00-1", "uniprot_id": "DC122_HUMAN", "id": "Q5VW00-1", "name": "DDB1- and CUL4-associated factor 12-like protein 2", "aln": "------------------------------MAQQQTGSRKRKAPAVEAGAGSSSSQG-------LAAADGEGPLLP-KKQKRPATRRRLVHYLKGREVGARGPAGLQGFEGELRGYAVQRLPELLTERQLDLGTLNKVFASQWLNARQVVCGTKCNTLFVVDVQSGHITRIPLMRDKEAGLAQAHQGCGIHAIELNPSKTLLATGGENPNSLAIYQLPTLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDMFNGSIAWHSEVGLPVYAHIRPRDVEAIPRASTNPSNRKVRALAFSGKNQELGAVSLDGYFHLWKARSTLSRLLSIRLPYCRENVCLTYCDELSLYAVGSQSHVSFLDPRQRQQNIRPLCSREGGTGVRSLSFYQHIITVGTGHGSLLFYDIRAQKFLEERASSSLDSMPGPAGRKLKLACGRGWLNQDDVWVNYFGGMGEFPNALYTHCYNWPEMKLFVAGGPLPSGLHGNYAGLWS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5VU92-1", "uniprot_id": "DC121_HUMAN", "id": "Q5VU92-1", "name": "DDB1- and CUL4-associated factor 12-like protein 1", "aln": "------------------------------MAQQQTGSRKRKAPAVEADAESSPSQG-------LAAADGEGPLLL-KRQRRPATYRSMAHYLKVREVGGWGPARLQGFDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQVVCGTKCNTLFVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLLSIRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGTGVRSLSFYRHIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWLNHNDFWVNYFGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CBW4-1", "uniprot_id": "DC121_MOUSE", "id": "Q8CBW4-1", "name": "DDB1- and CUL4-associated factor 12-like protein 1", "aln": "MRQADSQTQPSPAEQETPQPAGPSNRSPPTMGPQQTGSRKRKAAEVDQGAGTSSSPGPAAPMATAGEGNAEGSMLLTKRPRRPVAHLSMVNYLKGRALGADGHPGLAGFEGDLRSYGVLRLPELLRERQLTLGPLNKVFASQWLNARQVVCGTKCNTLFVVDVKTDHIMRIPLMRDRVPDLSRGPPSCGIHAVELNPSKTLLATGGENPNSLAVYQLPTLDPVCLGDCQGHRDWIFAIAWMSDTVAVSGSRDGTVALWKVDPDMFNGSIAWHKDAGLPVYAHISPTDMEAIPKATTNPGNRKVRALAFSNKNQELGAVSLDGYFHLWKARSSLSRLLSLRLPYCRENVCLTYCDEFSLYAVGSQSHVSFLDLRQGQQNIPPLCSREGGTGVRSLSVHQHIVTVGTGHGSLLFYDIRAQKFLEERSAANPDMFPVPSGRKLKLTCGSGWINQDDLLENYVAGVEDFPNALYTHCYNWPEMKLFVGGGPLASGLHGNYAGLWS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4ABX0-1", "uniprot_id": "D4ABX0_RAT", "id": "D4ABX0-1", "name": "", "aln": "MRQADSQTQPSPAEQEMPQPAGPSNSSPPTMGPQQTGSRKRKAAEVDQGAGTSSSPGPAAAMATVGAGNAEGSLMLTKRPRRPIAHLSMVNYLKGRALGADGHPGFAGFEGDLRSYGVLRLPELLRERQLTLGPLNKVFASQWLNARQVVCGTKCNTLFVVDVKTDHIMRIPLMRDRVPDLSRGPPSCGIHAVELNPSKTLLATGGENPNSLAVYQLPTLDPVCLGDCQGHRDWIFAIAWMSDTVAVSGSRDGTVALWKVDPDMFNGSIAWHKDAGLPVYAHISPTDMEAIPKATTNPGNRKVRALAFSNKNQELGAVSLDGYFHLWKARSSLSRLLSLRLPYCRENVCLTYCDEFSLYAVGSQSHVSFLDLRQGQQNIPPLCSREGGTGVRSLSVHQHIVTVGTGHGSLLFYDIRAQKFLEERSAANPDMFPVPSGRKLKLTCGSGWINQDDLLENYVAGVEDFPNALYTHCYNWPEMKLFVGGGPLASGLHGNYAGLWS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VGE3-1", "uniprot_id": "DCA12_DROME", "id": "Q9VGE3-1", "name": "DDB1- and CUL4-associated factor 12 homolog", "aln": "----------MFNGMVRTIRDSVVGTYPSCHVSSRLEERRAKQRAMRQERRRKPDKPDD---FVTYEDSGSDEETPQQQEEVLNTSYNLCDYLRSRESGLRDRRSVN----VEYTSRYVLTHDMLRETQISLGYINKVFCSKWLSSRQVVFGTKCNKLLVYDVNMRRVDAIPTLSNSRANHPEVQG--GLHAIELSPSRSFLATGARNSSDIAVYRLPTLDPVCVGE-GGHRDLIMGMCWLDDQFLVSGSKDSRMALWRINED--HMEFPDGGEEACPTFATIHPLSVKEVRTAQR------IRSLCFNKEFKEIAALSLNGYIHIFNAET-FKQTLSRKLPNCQDNVSIAYHSDG-LYAVGCRSYTILLDAR-TLQTIKKITSRYSGCGIRATSFEGNLLTVGTGLGMLLFYDIRAGKYLES---------SVNASRTVALKCSKGIVYPEDEMDGFQQ--VKYVPAIYTHCYDSTRMRLFAAGGPLPATLVGNYAGVWQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .*: * : ... .... :: . : : .**: * * . . ::* * *: ** :****.*:**.:**** *****.*:* **: :: ** : : . .. *:**:**.**:::****..*...:*:*:**:***:*:*: **:* *:.:.*:.* . ****:*. :***::: * . .. : . *.:* * * .:: : * :*:*. . : :*:.*:**:**:*:::* : :.: ** :** ::**.::* .: :****.:*:. :** * *.* : ** .* *:*: *. :::***** * *****:** *:**. . : *.: * *. * : :* .: : *:*****: ..*:**..****.: * *****:*.", "identical_positions": 148, "similar_positions": 147, "identity": "29.54%" }, { "cls_id": "homologset.agr.MGI:2444465", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZG74-1", "uniprot_id": "D3ZG74_RAT", "id": "D3ZG74-1", "name": "FRAS1-related extracellular matrix protein 2", "aln": "MAGPRGALGHPPGPALPLGGPRRRRAEFPALPIGLWRSLQRLALHTRRVNCRNSNACNLHATRTPGMATRGRWTAKYSNFQSILTQSPR---LLLLLLSLVSRVSTQDAAPGAAFLSLGLSGTSG-VPTEEAIVVANRGLRVPFGREVWLDPLRDLVLQVQPGDRCTVAVLDNDALAQRPGRLSPKRFACDYGPGEVRYSHLGARSPSRDRVRLQLRYDAPGGAIVLPLALEVEVVFTQLEVVTRNLPLVVEELLGTSNALDARSLEFAYQPETEECRVGILSGLSALPRYGELLHYPQVPGGTGERGSSETPLMDCKAFQELGVRYRHTALSHSPNRDWLPMVVEIHSRGAPVGSPALKREHFQVLVRIRGGAENTAPKPSFVAMMMMEVDQFVLTALTPDMLAAEDAESNPDLLIFNLTSAFQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQPPSEDSDQERLFELELEVVDPEGAASDPFAFMVVVKPMNTLAPVVTRNTGLILYEGQYRPLTGPVGSGPQNLVISDEDDLEAVRLEVVAGLRHGHLVILGSPSSDPAPKTFTVAELAAGQVVYQHDDRDGSLCDNLVLRMSDGGGRHQVQFLFPITLVPVDDQPPVLNANTGLTVAEGDTVPIPPSTLSATDMDSDDSQLLFVLEPPFSSSGRLLLRQTHAPQEEQ----GLWHKQGSFYERMVTEWRQQDITEGKLFYRHSGPHSPGPVMDQFLFRVQDNQDPPNQSGIQRFVIRIHPVDRLPPELGSGCPLRMVVQESQLTPLRKRWLHYTDLDTDDRELHYTVTQPPTDTDENHSPAPLGTLVFTDNPSVVVTHFTQAQVNHHKIAYRPPGQELGVAARVAQFQFQVEDRAGNVAPGTFTLYLQPVDNQPPEIVNTGFTVEEKGHHVLRETELHVSDVDTDVAHISFTLTQAPKHGHLQISGRPLHVGGQFRLEDIKQGRISYLNSGDESLTDSCSLEVSDRHHVVPITLRVNVRPADREGAMSVLPAGTLESYLDVLENGATEVTANIIKGTYRDTDDLMLTFLLEGPPLYGEILVHGAPAEQFTQRDILEGSVVYAHTSGEIGLLPKADSFNLSLSAMSQEWRIGSSVIQGVTVWVTILPVDSQAPEISVGEQFVVLEGDKSLISLTHLSAEDVDSLMDDLLCTIVIQPTSGYVENISPAPGSEKSRAGIAISAFTLKDLRQGHINYVQSVHRGVEPVEDRFIFRCSDGINFSERQIFPIVIIPTNDEQPEMFMREFMVMEGMSLVVDTPILNAADADIPRDDLTFTITRFPTHGHIMNQLINGTVLVESFTLDQIIESSSIIYEHDDSETQEDSFVIKLTDGKHSVEKMALIMVIPVDDETPRMAINNGLEIEIGETKVINNKVLAATDLDSDDKSLVYIIRYGPGHGLLQR-------RKPLGVFENITLGMNFTQDEVDRNLIQYVHFGQEGIRDLIKFDVTDGTNALIDRYFYVSIGSVDIVFPDVVSKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDQRGLSITSFTQLQLAGNKIYYIHTAEDEVKMDSFEFQVTDGRNPVFRTFRISISDVDNKKPVVTIHNLVVSESESKLITPFELTVEDRDTPDRLLKFIVTQVPVHGHLLFNNTRSVMVFTKQDLNENLISYKHDGTESTEDSFSFTVTDGTHSDFYVFPDTVFETRRPQVMKIRVLPVDNRVPQIVVNKGASTLRTLPTGHLGFMITSKILKVQDRDSLHFSLRFIVTEAPQHGYLLNLGQG--NHSVTQFTQADIDDMKICYVLRERANATSDVFHFIVEDDGGNRLTNQHFRLNWAWISFEKEYYLINEDSKFLDIVLKRRGYLGETSFISISTRDGTAEKDKDFKGKAQKQVQFNPGQTRASWRVRILSDGEHEHSETFQVVLSEPVLAVLEFPEVTTVEIIDPGDESTVFIPQSEYSVEEDVSELFIPIRRSGDISQELMVICYTQQGTATSTVRTSVLSYSDYISRPEDHSSVIRFDKDEREKMCRVVVIDDSLYEEEETFQVLLSMPMGGRIGNKFPGANVTILTDKDDEPAFYFGDTQHSVDESAGYVEVQVWRTGTDLTKPSSVTVRSRKTEPPSADAGTDYVGISRNLDFAPGVSMQTVRVVILDDLGRPVLEGIEKFELVLRMPMNAALGEPSKATVSINDSASDLPKMQFKERVYTCSENDGHVVAMIYRSGDLQHRSSVRCYTRQGSAQVMMDFEERPNTDISIVTFLPGESEKPCVLELMDDDLYEDVEELRLVLGTPQGSSAFGAAVGEQNETLIKIQDDADKAVIKFGETKFSVTEPSRPGESVVVKIPVIRQGDTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHTVEIEVIFDGVREMREAFTVHLKPDENMVAETQTTKAIVYIEEINSMADVTFPSVPHIVSLMVYDDTFKGREDAGPVSGYPIICITACNPKYPDYDKTGSICASENINDTLTRYRWLTSAPTGPDGVASPMREVDFDTFFTSSKMITLDSIYFQPGSRVQCAARAVNTNGNEGLELMSPIVTIAREEGLCQPRVPGVVGAEPFSAKLRYTGPEDPDFANLIKLTVTMPHIDGMLPVISTRELSNFELTLSPDGTRVGNHKCSNLLDYSEVRTHHGFLTNATKNPEVIGETYPYQYSAPVRGSSTLRFYRNLNLEACLWEFVSYYDMSELLADCGGTIGTDGQVLNLVQSYVTLRVPLYVSYVFHSPVGVGGWQHFDLKSELRLTFVYDTAILWNHGIGSPPEAELQGSLYPTSMRIGEEGRLAVNFKTEAQFHGLFVLSHPASFTS--------SLIVSADHPGLTFSLRLIRSEPTYNQPVQQWSFISDFAVRDYSGTYTVKLVPCTTPSNQEYRLPVTCNPREPVTFDLDIRFQQVSDPVAAEFSLNTHMYLLSKKSLWLSDGSMGFGQESDVAFAEGDVIYGRVMVDPVQNLGDSFYCSIEKVFLCTGDDGYVPKYSPANAEYGCLADSPSLLHRFKIVDKAQPETQATSFGDVLFNAKLAVDDPEAALLVNQPGSDGFKVDSTPLFQVALGREWYIHTIYTVRSKGTSHRGIGKRSLEYQYHSVVQHGPPQATTKSWKKRAVRSTPSLAGEIGAENNRGTNIQHISLDRRGKRQVPHGRIPPDGILPWELNSPSSEMSLVTVLGGISVGLLAVCLAVAVAVMCRNR-SIKGKDAPKGSGSTEPMMSPQSHYN-DSSEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NVD0-1", "uniprot_id": "FREM2_MOUSE", "id": "Q6NVD0-1", "name": "FRAS1-related extracellular matrix protein 2", "aln": "------------------------------------------------------------------MASRARRTAKFSSFQPILAQSPRLL-LLLLLLSLVSYVSTQAAGPGAALQSLGLSGTSG-VPTEEAIVVANRGLRVPFGREVWLDPLRDLVLQVQPGDRCTVTVLDNDALAQRPGHLSPKRFACDYGPGEVRYSHLGARSPSRDRVRLQLRYDAPGGAIVLPLALEVEVVFTQLEIVTRNLPLVVEELLGTSNALDDRSLEFAYQPETEECRVGILSGLSALPRYGELLHYPQVQGGAGDRGTSKTLLMDCKAFQELGVRYRHTAPSRSPNRDWLPMVVELHSRGAPEGSPALKREHFQVLVRIRGGAENTAPKPSFVAMMMMEVDQFVLTALTPDMLAAEDAESDPDLLIFNLTSAFQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQPPSEDSDQERLFELELEIVDPEGAASDPFAFMVVVKPMNTLAPVVTRNTGLILYEGQYRPLTGPIGSGPQNLVISDEDDLEAVRLEVVAGLRHGHLVILGSPSSDSAPKTFTVAELAAGQVVYQHDDKDGSLSDNLVLRMSDGGGRHQVQFLFPITLVPVDDQPPVLNANTGLTVAEGETVPIPPLTLSATDIDSDDSQLVFVLLPPFSSLGHLLLRQRHVPQEEQ----GLWQKQGSFYERTVTEWRQQDITEGKLFYRHSGPHSPGPVMDQFMFRVQDNHDPPNQSGIQRFVIRIHPVDRLPPELGSGCPLRMVVQESQLTPLRKRWLHYTDLDTDDRELQYTVTQPPTDTDENHSPAPLGTLVFTDNPSVVVSHFTQAQVNHHKIAYRPPGQELGVAARVAQFQFQVEDRAGNVAPGTFTLYLQPVDNQPPEIVNTGFTVEEKGHHILRETELHVSDVDTDVTHISFTLTQAPKHGHMQISGRPLHVGGQFHLEDIKHGRISYWNSGDESLTDSCSLEVSDRHHVVPITLRVNVRPGDREGPMSVLPAGTLESYLDVLENGATEVTANIIKGAYQGTDDLMLTFLLEGPPSYGEILVNGAPAEQFTQRDILEGSVVYAHTSGEIGLLPKADSFNLSLSAMSQEWRIGSSIVQGVTVWVTILPVDSQAPEISLGEQFVVLEGDKSVISLTHLSAEDMDSLKDDLLCTIVIQPTSGYVENISPAPGSEKSRAGVAISAFTLKDLRQGHINYVQSVHRGVEPVEDRFIFRCSDGINFSERQIFPIVIIPTNDEQPEMFMREFMVMEGMSLVVNRLILNAADADIPRDDLTFTITRFPTHGHVMNQLINGTVLVESFTLDQIIESSSIIYEHDDSETQEDSFVIKLTDGKHSVEKMVLIVVIPVDDETPRMTINNGLEIEIGETKVINNKVLMATDLDSDDKSLVYIIRYGPGHGLLQR-------QKPLGAFENITLGMNFTQDEVDRNLIQYVHFGQEGIRDLIKFDVTDGTNALIDRYFYVTIGSVDIVFPDVVSKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDRRGLSITSFTQLQLAGNKIYYIHTAEDEVKMDSFEFQVTDGRNPVFRTFRISISDVDNKKPVVTIHNLVVSESESKLITPFELTVEDRDTPDRLLKFIVTQVPVHGHLLFNNTRSVMVFTKQDLNENLISYKHDGTESTEDSFSFTVTDGTHSDFYVFPDTVFETRRPQVMKIQVLPVDNSVPQIVVNKGASTLRTLATGHLGFMITSKILKVEDRDSLHFSLRFIVTEAPQHGYLLNLGQG--NHSVTQFTQADIDDMKICYVLRERANATSDMFHFIVEDDGGNRLTNQHFRLNWAWISFEKEYYLINEDSKFLDIVLTRRGYLGETSFISIGTRDGTAEKDRDFKGKAQKQVQFNPGQTRASWRVRILSDGEHEHSETFQVVLSEPVLAILEFPTVTTVEIIDPGDESTVFIPQSEYSVEEDVGELFIPIRRSGDISRELMVICYTQQGTATSTVRTSVLSYSDYISRPEDHSSVIRFDKDEREKMCRILVIDDSLYEEEETFQVLLSMPMGGRIGDKFPGANVTILTDRDDEPAFYFGDTQYSVDESAGYVELQVWRTGTDLSKPSSVTVRSRKTESLSADAGTDYVGISRNLDFAPGVNMQTVRVVILDDLGRPILEGIEKFELVLRMPMNAALGEPSKATVSINDSASDLPKMQFKERVYTCNENDGRVVAMIYRSGDIQHRSSVRCYTRQGSAQVMMDFEERPNTDVSTVTFLPGEMEKPCVLELMDDAVYEDVEELRLVLGTPQGSSAFGAAVGEQNETLIKIQDEADKAVIKFGETKFSVTEPSRPGESVVVKIPVIRQGDTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHTVEIEVIFDGVREMREAFTVHLKPDENMVAETQATKAIVYIEEIHSMADVTFPSVPHIVSLLIYDDPSKGREDTGPVSGYPVVCITACNPKYPDYEKTGSICASENINDTLTRYRWLISAPAGPDGVTSPMREVDFDTFFTSSKMITLDSIYFQPGSRVQCAARAVNTNGNEGLELMSPIVTIGREEGLCQPRVPGVVGAEPFSAKLRYTGPEDPDFANLIKLTVTMPHIDGMLPAISTRELSNFELTLSPDGTRVGNHKCSNLLDYNEVKTHHGFLTNATKNPEVIGETYPYQYSVPVRGSSTLRFYRNLNLEACLWEFVSYYDMTELLADCGGTIGTDGQVLNLVQSYVTLRVPLYVSYVFHSPVGVGGWQHFDLKSELRLTFVYDTAILWNHGIGSPPEAELQGSLYPTSMRIGEEGRLAVNFKTEAQFHGLFVLSHPASFTS--------SLIVSADHPGLTFSLRLIRSEPTYNQPVQQWSFVSDFAVRDYSGTYTVKLVPCTTPSNQEYRLPVTCNPREPVTFDLDIRFQQVSDPVATEFSLNTHMYLLSKKNLWLSDGSMGFGQESDVAFAEGDVIYGRVMVDPVQNLGDSFYCSIEKVFLCTGDDGYVPKYSPANAEYGCLADSPSLLHRFKIVDKAQPETQATSFGDVLFNAKLAVDDPEAVLLVNQPGSDGFKVDSTPLFQVALGREWYIHTIYTVKSKDNTHRGIGKRSLEYQYHSVVHPGPPQATTKSWKKRAVRSTPSLAGEIGAENNRGTNIQHISLNRRGKRQVPHGRIPPDGILPWELNSPSSEVSLVTVLGGLTVGLLTVCLAVAAAVMCRNR-STKGKDTPKGSGSTEPMMSPQSHYN-DSSEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SZK8-1", "uniprot_id": "FREM2_HUMAN", "id": "Q5SZK8-1", "name": "FRAS1-related extracellular matrix protein 2", "aln": "----------------------------------------------------------MHSAGTPGLSS--RRTGNSTSFQPGPPPPPRLLLLLLLLLSLVSRVPAQPAAFGRALLSPGLAGAAG-VPAEEAIVLANRGLRVPFGREVWLDPLHDLVLQVQPGDRCAVSVLDNDALAQRPGRLSPKRFPCDFGPGEVRYSHLGARSPSRDRVRLQLRYDAPGGAVVLPLVLEVEVVFTQLEVVTRNLPLVVEELLGTSNALDARSLEFAFQPETEECRVGILSGLGALPRYGELLHYPQVPGGAREGGAPETLLMDCKAFQELGVRYRHTAASRSPNRDWIPMVVELRSRGAPVGSPALKREHFQVLVRIRGGAENTAPKPSFVAMMMMEVDQFVLTALTPDMLAAEDAESPSDLLIFNLTSPFQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQPPSEDSDQERLFELELEVVDLEGAASDPFAFMVVVKPMNTMAPVVTRNTGLILYEGQSRPLTGPAGSGPQNLVISDEDDLEAVRLEVVAGLRHGHLVILGASSGSSAPKSFTVAELAAGQVVYQHDDRDGSLSDNLVLRMVDGGGRHQVQFLFPITLVPVDDQPPVLNANTGLTLAEGETVPILPLSLSATDMDSDDSLLLFVLESPFLTTGHLLLRQTHPPHEKQELLRGLWRKEGAFYERTVTEWQQQDITEGRLFYRHSGPHSPGPVTDQFTFRVQDNHDPPNQSGLQRFVIRIHPVDRLPPELGSGCPLRMVVQESQLTPLRKKWLRYTDLDTDDRELRYTVTQPPTDTDENHLPAPLGTLVLTDNPSVVVTHFTQAQINHHKIAYRPPGQELGVATRVAQFQFQVEDRAGNVAPGTFTLYLHPVDNQPPEILNTGFTIQEKGHHILSETELHVNDVDTDVAHISFTLTQAPKHGHMRVSGQILHVGGLFHLEDIKQGRVSYAHNGDKSLTDSCSLEVSDRHHVVPITLRVNVRPVDDEVPILSHPTGTLESYLDVLENGATEITANVIKGTNEETDDLMLTFLLEDPPLYGEILVNGIPAEQFTQRDILEGSVVYTHTSGEIGLLPKADSFNLSLSDMSQEWRIGGNTIQGVTIWVTILPVDSQAPEIFVGEQLIVMEGDKSVITSVHISAEDVDSLNDDILCTIVIQPTSGYVENISPAPGSEKSRAGIAISAFNLKDLRQGHINYVQSVHKGVEPVEDRFVFRCSDGINFSERQFFPIVIIPTNDEQPEMFMREFMVMEGMSLVIDTPILNAADADVPLDDLTFTITQFPTHGHIMNQLINGTVLVESFTLDQIIESSSIIYEHDDSETQEDSFVIKLTDGKHSVEKTVLIIVIPVDDETPRMTINNGLEIEIGDTKIINNKILMATDLDSEDKSLVYIIRYGPGHGLLQR-------RKPTGAFENITLGMNFTQDEVDRNLIQYVHLGQEGIRDLIKFDVTDGINPLIDRYFYVSIGSIDIVFPDVISKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDQPGVSITSFTQLQLAGNKIYYIHTADDEVKMDSFEFQVTDGRNPVFRTFRISISDVDNKKPVVTIHKLVVSESENKLITPFELTVEDRDTPDKLLKFTITQVPIHGHLLFNNTRPVMVFTKQDLNENLISYKHDGTESSEDSFSFTVTDGTHTDFYVFPDTVFETRRPQVMKIQVLAVDNSVPQIAVNKGASTLRTLATGHLGFMITSKILKVEDRDSLHISLRFIVTEAPQHGYLLNLDKG--NHSITQFTQADIDDMKICYVLREGANATSDMFYFAVEDGGGNKLTYQNFRLNWAWISFEKEYYLVNEDSKFLDVVLKRRGYLGETSFISIGTRDRTAEKDKDFKGKAQKQVQFNPGQTRATWRVRILSDGEHEQSETFQVVLSEPVLAALEFPTVATVEIVDPGDEPTVFIPQSKYSVEEDVGELFIPIRRSGDVSQELMVVCYTQQGTATGTVPTSVLSYSDYISRPEDHTSVVRFDKDEREKLCRIVIIDDSLYEEEETFHVLLSMPMGGRIGSEFPGAQVTIVPDKDDEPIFYFGDVEYSVDESAGYVEVQVWRTGTDLSKSSSVTVRSRKTDPPSADAGTDYVGISRNLDFAPGVNMQPVRVVILDDLGQPALEGIEKFELVLRMPMNAALGEPSKATVSINDSVSDLPKMQFKERIYTGSESDGQIVTMIHRTGDVQYRSSVRCYTRQGSAQVMMDFEERPNTDTSIITFLPGETEKPCILELMDDVLYEEVEELRLVLGTPQSNSPFGAAVGEQNETLIRIRDDADKTVIKFGETKFSVTEPKEPGESVVIRIPVIRQGDTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHVVEIEVTFDGVREMREAFTVHLKPDENMIAEMQLTKAIVYIEEMSSMADVTFPSVPQIVSLLMYDDTSKAKESAEPMSGYPVICITACNPKYSDYDKTGSICASENINDTLTRYRWLISAPAGPDGVTSPMREVDFDTFFTSSKMVTLDSIYFQPGSRVQCAARAVNTNGDEGLELMSPIVTISREEGLCQPRVPGVVGAEPFSAKLRYTGPEDADYTNLIKLTVTMPHIDGMLPVISTRELSNFELTLSPDGTRVGNHKCSNLLDYTEVKTHYGFLTDATKNPEIIGETYPYQYSLSIRGSTTLRFYRNLNLEACLWEFVSYYDMSELLADCGGTIGTDGQVLNLVQSYVTLRVPLYVSYVFHSPVGVGGWQHFDLKSELRLTFVYDTAILWNDGIGSPPEAELQGSLYPTSMRIGDEGRLAVHFKTEAQFHGLFVLSHPASFTS--------SVIMSADHPGLTFSLRLIRSEPTYNQPVQQWSFVSDFAVRDYSGTYTVKLVPCTAPSHQEYRLPVTCNPREPVTFDLDIRFQQVSDPVAAEFSLNTQMYLLSKKSLWLSDGSMGFGQESDVAFAEGDIIYGRVMVDPVQNLGDSFYCSIEKVFLCTGADGYVPKYSPMNAEYGCLADSPSLLYRFKIVDKAQPETQATSFGNVLFNAKLAVDDPEAILLVNQPGSDGFKVDSTPLFQVALGREWYIHTIYTVRSKDNANRGIGKRSVEY--HSLVSQGKPQSTTKSRKKREIRSTPSLAWEIGAENSRGTNIQHIALDR-TKRQIPHGRAPPDGILPWELNSPSSAVSLVTVVGGTTVGLLTICLTVIAVLMCRGKESFRGKDAPKGSSSSEPMVPPQSHHN-DSSEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5C5-1", "uniprot_id": "A0ACD6B5C5_DANRE", "id": "A0ACD6B5C5-1", "name": "", "aln": "-----------------------------------------------------------------------------MELHR----------FLLLLLSLTG-------SSVSALETHGLSYASKPELSEDAILVANNGIHVPFGRSVYIDPINDLVIELQPGDRCTITVLDNDPLSQRPGHVSPKKFPCEFGPNDVRYSHFGSRSPAGDRVKLQLRYDTQTETIIIPFMLEVEVVFTQLEVVTKNMPLVVDKLHGTSNPINKKILDFTYEKDSEQCEVTSLAASSVLPKYGKVVDDRKLEK-----------MMSCELFLKSNIRYEHTSSHKSPNKDYIPMVVELRNK----ENNLLKQEFFHVMIRIKEGEENTPPRPSFVAMMMMEVDQFVMTALTPDMLAAEDTESNTDDLIFNITSPLSIEEGYIVSTDDRNLPITSFYQKDLKDLKIAYKPPSLDSDTERIFQIEFEVIDPDGGISDPFAFMIVVKPMNTLAPIVTKNSGQLLYEGQSRSLFTQN-----NLEISDEDNLDSVRITVVDGLRHGVLTVLGSNR-----KYFTPADLEVGIVVYQHDGSD-TYSDNIIFRMTDG--KNEVEFLFPITIVPTDDEPPIINANTGLILFKNQMVPISQLMLSAADIDSEDSIIKFTIEPPFSAIGEVVLRQSEAPEDPSS---WKFNADDGVYEKVVTEWLQKDITDEKLFYRHTGPHITETVTDQFVFKVKDDADPPNQSSENNFIIKILPIDDIPPVLFPGTTLQMTVHEYQLTHLSKNVLRYTDLDSEDRDLKYTITQAPTDMDENN-PVKFGSIVLTDSPDTDVTEFTQAQINHHKISYSPPDLELGIIPHVVQFHFTVEDTAGNGADGVFTIFLQPVNNKPPQITNSGFTVLERGVHVITSAELDANDLDTDIKLISFTLSQTPLHGHLQDTFTDLKKGSYFNLMDISDGQVSYVHNGDETTSDSFKLDVSDGVHVVTITVKVTVKLIDDETPTLSLTKGTFGSRLDVLENGATEITPNVIQGKDEDTDDLQLTFIVEEAPKFGEILVNGVSSSRFTQADIISGLVVYAHTSGEIGLTSIEDFFSLTLSDMSDEWNVGGNRVHGVRVHVTILPVDNQTPLVTVGPTFNVFEADKNIIGSHQIKVEDADTPNEDILCTIIVQPTSGYVENISPAPGSEKSRAGTAVSAFTISDVNEGHIYYVQSIHKGVEPVEDRFTFRCSDGVNFSERQFFPIVIIPTNDEKPEIFMREVVVMEGMNVIIDTPLLNGVDADVPAQELMFIITKLPNHGFILNQLASGSVPVTNFTLEQIKEASSIIYEHDDSETTEDKFDVLLTDGKHSAEGTVMIMIIPVDDETPRLAINDGLEIEIGETKEINAKVLKATDLDSDDESLTFIIRYGPAQGLLYRKLAGSVEKRSAGSTENITVGMNFTQNEVNRGLILYTHNGQEGMRDLVKFDVTDGINPLIDRYFYITVGSIDMVFPDVISKGVSLKEGGKVTLTTNLLSTSDLNSPDENLVFTITRAPVRGHLESTDTPGMPIVSFTQLQLAGSKIYYIHTADDEVKMDSFEFEVTDGYNPVFRTFRVSIVDVDNKKPVLTIHDLLVTEGQTKLITPFELTVEDQDTAEHLLKFKVSQLPIHGKLLFNNSQPVTSFTKQDLNENMISYKHDGTESKKDSFSFTVTDGTHSDFFVFPDTIFETQRPQTMKINIVSVDNGVPQIEVNKGAPTLKVLFAGHLGYQITSKVLKAVDRDSNPEALIFHITTQPEHGYLISLDRGTENDSINTFTQADINDLKICYILKDENNATSDVFSFTVEDNGGNKLKNQPFHLNWSWISLEKPNYVVDEHDKVLEVTLRRRGFLGETSFVGIGTLDGSAEKEKDFLGKSQKQVQFNPGQTTASWKVRVLSDGKYEQSETFQIVLTEPVMGVLEAPAVATVEIVDPGDESMVFFPQAGFAVEEDIGELLVPVRRTGDVSQELMVVCHTQQDSATGTVPTSVLSYSDYISRPEEQVSILRFDKDETEKHCRVVIIDDSLYESEESFNVTLSMPIGGRLGPEYPTVNIRILPDQDDAPVFYFGSQEYHVDESDGHVEVRVWRTGTDLSKTATVTVRSRKTDPVSAEAGVDYVGISRNLDFAPGVSMQTVRVTVLDDLGQPVLEGTERFELVLRMPSNGILGEPAKVTVFINDSISDLPKVQFKQAVVTAEESEGHVTVMVHRSGDIKHKSSVRCYTRQGSAQVVYDFEERPNTDASIVTFLPGEVDKPCVLKLVDDSIHEEEEELRLVLGNAKSDSPYGASIGNQNETLIKIKDNADKSIIKFAETKFSVSEPKESGQVTLVKIPIRRTGDASKVSLVRVHTKDGSAISGEDYHPISLDVEFKAEEIEHVVEVEVLFDGIREMREAFTVHLKPDENMIAEIQMTKAIVYIEETNSMADVTFPSLPHIVSLLHYDNIRTSKQSAHPPAGYPVVCVTACNPKYPDYDKTGSICISERINNTLTRYRWLISAPSGPDGVTSPMREADFDTFFTSSKMITLDSIYFQAGSRVQCAARAVNSNGDEGLELSSPIVSISMEEGMCQPRKLGTVGAEPFSAKLRYTGAEDLQYANLIKLTVTMPHIDGMLPVVSTRALSNFDLTLSPDGTRVGNHRCSNLLDFNEVSTRHGFLTKATRNIQSVGETLPYQYSPVLRGQGTLRFYRNLNLEACLWEFVSYYDMSELLTDCGGTIGTDGQVLNLVQSYVTLRVPLHVSYVFHSPVGAGGWQHFDLHSELRLTFVYDTAILWKDGVGSQTQADLQGALYPTSMRINEQGRLVVNFRTEARFRGLFVVGHPANLRSLKTTASTVSTVMSADHPGLTFNLTLVRTEPTYSQPVQQWMFISDFAVRDYSGTYTVSLIPCTAALNVEFTVPPVCNPREAITFDLDIRFQQVSDPVAVEFSLNTQMFLLSKKVLWLSDGSMGFGQESDAAFSEGDVIYGRVMVDPVQNLGDSFYCNIEKVYLCTGADGYVPKYNPSKSEFGCLADSPSLLYRFKIIDKAQPETQARSFGNVDFNALLAVDDPSALSLVKQPGSDGFRLHSTPLFQVAVGREWFIHTIYTVRSKDNAKRGIGKRSVEQ---HLITSGDLKESRR-RSRRSNRDVPTLAEQIGPENNRGTNIMHIALDR-SRRTGSEEELFADGLSPRGLSGRQAEEEAVTVAGALVGLLLTVLVFVALALVVRSR-RTPAKKAPRVSPSLQPVIVRSSLDNGDSSEV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: :*******.. . *: : **: :: :*:**::**.*::*****.*::**:.***:::******:::*****.*:****::***:*.*::**.:*****:*:***: ***:******: ::::*: ***********:**:*:****::* ****.:: : *:*::: ::*:*.* *:. ..**:**:::. :: :*.*: * : .:**.**: :***:*::*****::.: . **:*.*:*::**: * ***.*:***************:************:** .* ****:**.:. :**:******.**::** *:**: *****:*** *** **:*::*:*::* :*. *******:*******:**:**:*:* :***** *.* ** *****:*::**: ** ***** *.:**: * ** *:* .* ******. * : .**:::** ** :::*:******:**.**:**::****** : :.: *** ***:*:**:** : *.: .** : *.::*** . *.: . :. :...**: **** *:***: :*****:*** . .* *** *:*:*: ******. :.*:*:* *:* :** * .* .*:*.*:* *** * *. *:*****::**:*:**:**.*** ***: *. :*::*:**.*.. *:.*****:*****:* **. ***: .:*.**:* *** *** * *.**::*:**:*:**:* *:***: *:* *:: .:**...*:***: *****:*:* ***:: : *: *. *.* **..*::** :.**:: :** .*:*** ***.**::*.*: * * . . **: * **********:*.*:*:* . **** ***::* .* :*****:* .:.:*** **:.* ***:******** . * *.*:** **:**.:*.. ::** : *******.*:* : :* : *:*.**.:* ::..** *: :*:****::********************** *:***.:.*:.:*** ****:*:********* ******:******:***********:**:****.:*****.:::: :**..***:* ::* * **::*.**.::*** .*:* * .***:** *:************ **.* : *******.* .:*::*********::**:*******:** ** *:* ******:*:**.:******.:*** * ::. * ****:******:**:*.** *.* ****:***:******* *.*******:::**:*:*****:****************:**********************:*****.** *:.*.*********.********:**********:**** ********:** ********:***.*:*:*.:.************:**.::**** ::*:*:**:*****::.* *********:**********.:************:**:*****:***:***.***.::.*** **** *****.**:.* :****: ****:**. **** :* * :* *:****:.*.:* *.*:. ******:*:****:*:: *****:* * ***.***:*. * *:***:***:** *:::*..*.*::.* ***:******:.*.* * :***::** **:*********** *:*:**:****::*:*****:**:***:. ** * *:****:*****. **:**: ::****:.**::*:**:**:*:****:*:***.:**.** **************:: *::****** ** **:::*******.**:*:* ****:***:* ::* .:: *:.*:** * ****. :: **** *:**::********:*.::********:. **:**.***************.**.***.:*****:* *** *:******** *. ****:*.** **** *****:***: : * .*.:*::..*::*:**::::**************: ********* * :****** :***:*:*:** ::*: ********..:..*.:**::*:******:*:*:***::***.******:**...*: .:::**: * **:****:********** *******:* ::*** * :*.**:** ***:*****************:** * ********* *********:*:****: **: ..::.: * :***::*:*******.**:****** **.**:******** ***:*****:*****.***********:********.************:**:***** ****:*. ***:**** *.**************.** :::*****************.:*** ****:*************:******:.** *::****.**:* : :*** ***** :**. ***********************:***:**************************:**********.********:***************:.*:** .:*:***:********.::***.*:*:***:*:****:.***.: * * ::*********.* *:*:****.****** *:**************.*:***:. : *: :* .*****.:****************.******:*:***** ***************.**:***:*******************.****:**** *******.* ::*:**********:****:********* ***:* *** ******.* **:*******::.********:****:*******:**..::*******:* :: * : : : .:* *..*:** :**.**.***** **:*:* :* .. . .**: * *.. .: . *** *. **:: : * .:: *.: .*.:*: * * :*:: .* * *****", "identical_positions": 1963, "similar_positions": 776, "identity": "60.38%" }, { "cls_id": "homologset.agr.MGI:2444477", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GKY7-1", "uniprot_id": "A0A8I6GKY7_RAT", "id": "A0A8I6GKY7-1", "name": "", "aln": "MEMDVEGVSP--------RPEPIPRSQGAGGACQAPPQPPQPQPQPQQQLAQDEVPSESAGAEDSDDPEARPNGERGESKSNATVRAYQSSKSRVTMSPGFSSQ-----------------------------WSNSQPAWNTYSFPRASLHYQSHASYTYCT-GHPVQSYAPAPH---------PMAPPSPSTNSSSN-----------------------------------SSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQSQNKHTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQVQSTSWTPHLPYIMQPTGAVITPTMDHPMSMQPTNIVGPLTQQMNHLSLGTAGTIQSQDRIMVLHQLLCQYMT-AAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDSSGQQQQLAVDTPSEHAPAYSFQQSKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWL5-1", "uniprot_id": "RBMS3_MOUSE", "id": "Q8BWL5-1", "name": "RNA-binding motif, single-stranded-interacting protein 3", "aln": "MGKRLD----------------------------------QPQMYPQ----------------------------------------------------------------------------------------------YTYYCP----QYLQTK-----------QSYAPAPH---------PMAPPSPSTNSSSN-----------------------------------SSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQGQSKHTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQVQSTSWTPHLPYIMQPTGAVITPAVDHPMSMQPTNIVGPLTQQMNHLSLGTAGTIQSQDRIMVLHQLLCQYMT-AAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDSSGQQQQLAVDTPSEHAPAYSFQQSKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XE24-1", "uniprot_id": "RBMS3_HUMAN", "id": "Q6XE24-1", "name": "RNA-binding motif, single-stranded-interacting protein 3", "aln": "MGKRLD----------------------------------QPQMYPQ----------------------------------------------------------------------------------------------YTYYYP----HYLQTK-----------QSYAPAPH---------PMAPPSPSTNSSSNNSS------------------------------NNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAAIQNGFYSSPYSIATNRMIPQTSITPFIAASPVSTYQVQSTSWMPHPPYVMQPTGAVITPTMDHPMSMQPANMMGPLTQQMNHLSLGTTGTIQSQDRIMILHQLLCQYMTAAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDTSGQQQQIAVDTSNEHAPAYSYQQSKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGV3-1", "uniprot_id": "F1QGV3_DANRE", "id": "F1QGV3-1", "name": "", "aln": "MGKRLE----------------------------------QQPMYPQ----------------------------------------------------------------------------------------------YTYYYP----HYLQTK-----------QSYAPPPP---------PMAPPSPSTNSSSH-----------------------------------SAAEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKASGVQAQMAKQQEQDPTNLYISNLPVSMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCDVVIQHFNGKFLKTPPGVPAPTEPLLCKFADGGQKKRQSQSKYPQNGRPWPREGESGMALTYDPT-AMQNGFYSSPYSISTNRMIAQTSITPFIAASPVSTYQVQSTSWMPHQQYVMQPTGAVITPTMDHTISMQPANMMGPLTQQMNHLSLGTTGTYMTAA---------------AAPMQGTYIPQYTAVPASAVSVEGVVTDASPQSVPASSQDASGQQQALGVENTSDHAPTYSFQPAK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MSV2-5", "uniprot_id": "SHEP_DROME", "id": "Q8MSV2-5", "name": "Protein alan shepard", "aln": "MHPRYSPAPPPQQQQQMGGPPHQQQGGGGGGGVSMRGPSNAQQLPPQIPRSQNYSNGSSSSAAAAPLTSRSAFPGAPLTASAVALKGALPQRPPAMTSPAAAAAGAALAAGAPYRGAASWTPQGYAPAAAAAAAAVAQQAAYRYTAPLPQPAYAAYTPHTATTPATTTVSFLSQPVDYYWYGQRVPTAASPSNTNSSSSSNTGSQSGTLSTSLSNTTNTNTNMGPNGTVQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDKTTNKCKGYGFVDFEQPAFAECAVKGLQGKGVQAQMAKQQEQDPTNLYIANLPPHFKETDLEAMLSKYGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNGN------TIPGAKDPLLVKFADGGPKKKNLFKTPDPNARAWRDVSAEGIPVAYDPT-MQQNGVSVN---VGTPIGVPYSRFS----APQVGGYPVAGSQWIPGYMMTQVDDQTSYSPQYMQMAAAPPLGVTSYKPEAVNQVQPRGISMMVSGD---------------TGVPYGTMMPQLATLQIGNSYISPTYPYYAPPPTIIPTMPMTDSEQASTAASPDEAYTQYPHQAAPK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . ** * * * *: . * * *.....***** ...************* ****:**:::* **.*:********.**:*********:.** *: ** .*:..*******************:*** :.* :** **. :*:*:******* : *:********* ***: :** ***: :*...:*** ****** **:: .. *.*.* . *:.::**** ***. . :.* :. : :: *. *. * * .:.* * : :* : : * .: . .: :*::. . : :. ** :** :.: :. . . :* .. .: :..:* . ...: . *..* : ", "identical_positions": 158, "similar_positions": 112, "identity": "25.53%" }, { "cls_id": "homologset.agr.MGI:2444479", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LET2-1", "uniprot_id": "A0ABK0LET2_RAT", "id": "A0ABK0LET2-1", "name": "THUMP domain-containing protein 1", "aln": "MAATAQQSPPSVGGKRKGKSQFLPAKRARRCDAGGPRQLEPGLQGILITCN-MNERKCVEEAYSLLNEYGDDMYGPEKFIDKDQQPSGSE------GEDD---------DAEAALKKEVG--DIKASTEKRLRRFQSVESGANNVVFIRTLG-IEPEKLVHHILQDMYKTK--KKKTRVILRMLPVSGTCKAFLEDMKKYAETFLEPWFK----APNKGTFQIVYKSRNNSHMNREEVIKELAGIVGSLNS--ENKVDLTNPEYTVVVEIIKAVCCLSVVK--DYVLFRKYNLQEVVKSAKD----SRPPPKLGNGKE----AQLEPGSKLSQNDPPKGKNNQQAAPESSEELGQTVPGSETQAGSEGGAKPEPESQGSEGPKTKELSLVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J36-1", "uniprot_id": "THUM1_MOUSE", "id": "Q99J36-1", "name": "THUMP domain-containing protein 1", "aln": "MATTAQQSPQPVAGKRKGKSQFLPAKRARRGDAGGPRQLEPGLQGILITCN-MNERKCVEEAYSLLNEYGDDMYGPEKFIDKDQQPSGSE------GEDD---------DAEAALKKEVG--DIKASTEKRLRRFQSVESGANNVVFIRTLG-IEPEKLVHHILQDMYKTK--KKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFK----APNKGTFQIVYKSRNNSHMNREEVIKELAGIVGSLNS--ENKVDLTNPEYTVVVEIIKAVCCLSVVK--DYVLFRKYNLQEVVKSAKD----SQPHPKLGNGKE----AKLEPDSKLSQSDPPEGN---QVAPESIEELGQTEPGSETQAGSEGDAKPEPESQVSEVPKTNENELS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXG2-1", "uniprot_id": "THUM1_HUMAN", "id": "Q9NXG2-1", "name": "THUMP domain-containing protein 1", "aln": "MAAPAQQTTQPGGGKRKGKAQYVLAKRARRCDAGGPRQLEPGLQGILITCN-MNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQQPSGSE------GEDD---------DAEAALKKEVG--DIKASTEMRLRRFQSVESGANNVVFIRTLG-IEPEKLVHHILQDMYKTK--KKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFK----APNKGTFQIVYKSRNNSHVNREEVIRELAGIVCTLNS--ENKVDLTNPQYTVVVEIIKAVCCLSVVK--DYMLFRKYNLQEVVKSPKDP---SQLNSKQGNGKE----AKLESADKSDQNNTAEGKNN-QQVPENTEELGQTKPTSNPQVVNEGGAKPELASQATEGSKSNENDFS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IIV9-1", "uniprot_id": "A0A0R4IIV9_DANRE", "id": "A0A0R4IIV9-1", "name": "THUMP domain-containing protein 1", "aln": "MSEARKRTRRRFGG---------HAHKKQK----GARELEVGAQGVLITCN-MNERKCTSEAFSLLSEYADELYGPE----QESLSEDEE------QEDE---------DAECALQREVS--QLQSSSKGRQQRFSAVDSGANNVVFIRTHG-VDPAQLVHHILSDLHLTR--KRKSRVILRMLPVSATCRAFPEDMQKLLSVFLQRWFL----APRHATFQICFKARNSSHSKREEVITAVAGLVGQLNP--LNKVDLTNPELSIIIEIIKSVCCVSVVT--DYMLFRKYNLQEVAKEPANQNTGSQKTPNQNTDPQETPSQNTDPQETPNQNTDSKEAANQNTDPQKTANESKGSQESANQTQEHGNGELQ-SSDVTVGNGAEEAEPE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZD8-1", "uniprot_id": "THUM1_DROME", "id": "Q9VZD8-1", "name": "THUMP domain-containing protein 1 homolog", "aln": "MEPASKKSKMGKNVK--------FNNNKKKYFHAKRQTLQPGQRGFFATCN-INEKACVRECYNLLNHYADILYGSEKPENEPEKKQPEEGAGGDAGEDDPKPAAGGTSDDDDDLEAAAA--KCREMLSQRKMRFQNVDTNTTNCVFIRTQL-EDPVALGKHIINDIATTG--KSMSRFVLRLVPIEVVCRANMPDIITAAGELFDKHFL----KEP-TSYGIIFNHRYNQQIKRDQIITQLAELVNSKNV--GNKVDLKEAKKSIIVEVLRGWCLLSVID--NYLECKKFNLAELANPSDK------KSSGEGDSKS------------------------------ETSEVANGNDKEQAESSEESKSNDDENKDSTENDK--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53072-1", "uniprot_id": "TAN1_YEAST", "id": "P53072-1", "name": "tRNA acetyltransferase TAN1", "aln": "MGEKRNRNGKDANS------------QNRKKFKVSSGFLDPGTSGIYATCSRRHERQAAQELQLLFEEKFQELYGDIKEGEDESENDEKKD---LSIEDQIK-------KELQELKGEETGKDLSSGETKKKDPLAFIDLNCECVTFCKTRKPIVPEEFVLSIMKDLADPKNMVKRTRYVQKLTPITYSCNAKMEQLIKLANLVIGPHFHDPSNVKKNYKFAVEVTRRNFNTIERMDIINQVVKLVNKEGSEFNHTVDLKNYDKLILVECFKSNIGMCVVDGDYKTKYRKYNVQQLYESKFR----------------------------------------------------KDEDKSVKQ----------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::. . :: *: * *. **. :*: .. * *:.. : :** . . . .: **: . *: . : : :: . .* :* * : *:.*: . :* : :: *: *.* :: . .: * .: : . * . :* ::* :. :* . :.***.: . :::* ::. :.*: :*:*: :: : : . : ", "identical_positions": 35, "similar_positions": 85, "identity": "8.95%" }, { "cls_id": "homologset.agr.MGI:2444480", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ACC4-1", "uniprot_id": "A0A8I6ACC4_RAT", "id": "A0A8I6ACC4-1", "name": "Dynein axonemal intermediate chain 7", "aln": "MGPKQKKAPTKKK-ITKAERLRLLQEEEEKRLKEEEEARLKYEKEEQERLEKQRIEREKWNLLEKKDLERRSEELEEL-ALLECCFPEAEKQKREMRVLAQWKHYTECDGSPDPRIAQEMNTFISLWEEEKNE-----------TFEQVMEKSKLVLSLIEKLKLILLETPSCDLDKSTVLQYQGSILRLQELLSLKVN----------VATELLLRQASNLADLDTGNMEKIIK----------------------------DENVTLYVWANLKKNPRYRTVKFSQTQVGFEIPRILATSNVALRLLHTHYDHITPLFSTVVTEEKHGS--------------------------------IVAENFKEEER-TEKAVPEENVFTEE-AADEAEQLKAEEER----------------------------------------------------------------------------------------------------------------------ELSSIPEEEVKFDPTVDTVTQKISDPEEEESQTTQF----------ELERKLLSETVSAAQLSLIENVLEMPETLEPYEVNMCHFAPLGGVYHLEILELP-------------------------------------------------------------------------------------------------------------PQSK---PVKGWVLAEIRQ--EGLQKFTYPPENT-----------EEPDPESAFP--------------------------------PIEVTLEIHESAIFFEDPQVVR-----------------------------------------------------WDAEGK------------FWRSDGVTCVYYNRENRLLTFSIDTMGPVTLIQDAHVNMPYQSWELSPLGMN--KALLMVTTVFIELQIHIKETHCMLAAVKLKGKSRELRVIGKWMTPIPFILALKEAGLNIFPAVYSHFYVVVN-NKVPQMELKAYRQMALLSSAFSFGWSKWNMVR----------EHISEE-EEQNTWALLMFSGDRAQMLKMQEESDQFSETLREGSEFHSTLYHMMKDFASPEATEKVRHSNCQFIDSVCYMLLSVRVLSYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6TDU8-1", "uniprot_id": "DNAI7_MOUSE", "id": "Q6TDU8-1", "name": "Dynein axonemal intermediate chain 7", "aln": "MAPKSKKAPSKKK-MTKAERLRLMQEEEERRLKEEEEARLKFEKEEQERLEIQRIEREKWNLLEKKDLERRSQELEEL-ALLEGCFPEAEKQKREIRALAQWKHYTECDGSPDPWVAQEMNTFISLWEEEKNQ-----------AFEQVMEKSKLVLSLIEKVKLILLETPTYELDHRTVLQHQGSILRLQELLSLKIN----------VATELLLRQASNLADLDTGNMEKIIK----------------------------DENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRILATSNVALRLLHTRYDHITPLFPIAVTEQNQNP--------------------------------VGAEQVNVEES-TEKAMTEEKLFTEEKAANEDEQPKAEQER----------------------------------------------------------------------------------------------------------------------ELN-LVQEENKYEAIENTVLQRTSDSEGEDSQTTQL----------ELEMKLLSEAVLAAQLCLVENVVELPEASQAYKVDLCHFSTLGGVYHLDVLELP-------------------------------------------------------------------------------------------------------------PQCK---PVKGWVLVEILQ--EGLQRFIYPPDTT-----------EEPDPDVTFP--------------------------------PIEVTLEIHKSVIFFERPRVVR-----------------------------------------------------WDNEGK------------FWRSDGISSVYYNREDRLLTFSMDTLGPVTLIQDAHVNMPYQSWEMSPCGMN--KVLLIVKTVFMELQIYIKENLCMLASVKLRGKGLEFHLKGKWMAPIPFILALKEAGLNIFPAVYSHFYVVIN-NKVPQVELKAYRQMALLSSAFSFGWSKWNMVCNSTRVVIRVREQLSEE-TEHHTWSLLMFSGDRAQMLKMQEENDKFSEALREGTEFHSTLYHMMKDFASPVAMERVRHSNCQFIDSVCYMLLSIRVLSYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TDU7-1", "uniprot_id": "DNAI7_HUMAN", "id": "Q6TDU7-1", "name": "Dynein axonemal intermediate chain 7", "aln": "-----MSGSKKKK-VTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEEL-YLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNE-----------TFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFG----------VATEILLKQASTLADLDSGNMEKVIK----------------------------DENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTS--------------------------------AVTELVKDDVKNVEKAIS-----------KEVEEESKQQER----------------------------------------------------------------------------------------------------------------------GSHLIQEEEIKVEEEQGDIEVKMSSAE-EESEAIKC----------EREMKVLSETVSAAQLLLVENSSEKPDFFEDNVVDLCQFTTLGGVYHLDILELP-------------------------------------------------------------------------------------------------------------PQCK---PVKGWMIVEILK--EGLQKYTYPPETT-----------EEFETENAFP--------------------------------PIEVTLEVHENVIFFEDPVVVR-----------------------------------------------------WDAEGK------------HWRTDGISNVSYKPKERLVTFSLDTFGPVTLIQDAHINMPYQSWELRPLDVN--KVLLTVTTVFTEIQIQIKENLCMLSSIKLKDKKHISILEGTWMTPIPFIIALKEAGLNIFPTRHSHFYVIIN-NKVPLVEVKAYRQMALLSSAFAFGWSKWNLLCNSTKVVFKVREHLTEACTENPNWALLMFSGDRAQRLKIKEESEAFSEALKEETEFHSTLYHMVKDFASEEAMEKVRSSNCQFVNSVCHMLLSTRLLSYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6H8T2-1", "uniprot_id": "DNAI7_DANRE", "id": "A6H8T2-1", "name": "Dynein axonemal intermediate chain 7", "aln": "MPPKDGKSAKKKGGISKAEKERLQREEEEKRQREAEEARLIAEREENERLERERIEQEKQHILELKDRERREDELNELRHILDENHFAVTVWEAECREKSKWERYMLCDGSPDPSVQPEINTYISLWRDDSEN-----------QIQKVLEECALTLELEKELEFLLGDGP----EPSIAEQYQETLLSLQNLIHYKLN----------QATEELLKFANYNSDIDTGNMQTVVK----------------------------DSNITLCLWANLNKNPRFKGYKFEEVGLGFELPKPLAVIEVAVRILHTRYDHLSHHSEREQLQKRRSM--------------------------------MEAILTQNTES--SAAVHN----------GKMEGERDESES----------------------------------------------------------------------------------------------------------------------SKQVDECHSVRSESRKRSAVSVISAKEGRKSSSIKLL------EEGESQMEEITTTLEADQHDPYPSPAEPVTDTDVHIVDLQQFTPLGGVFYFDLFHMP-------------------------------------------------------------------------------------------------------------PQSR---TVKGWEMRELLD--TGLQVFPYPTEQSRIQSSTSVKLDEHSNTTVASL--------------------------------PVGVTVALPHSVLFLEDPQVAR-----------------------------------------------------WDPIGQ------------HWRTDCISETSYDAELRTISFQMTAFYAFTLLQETYANMPFQSWELRPLGQD--SALFTITGALIEVSITVKGKQCMLHTEETKDLDR---LLGKWMSPSELQKAMRKAGINIFVNEYSDKYVSIN-LKDPLIEHAVYEQMALMSSAVAFSWSRWNAQCRQEHLVLQACEQLEVGPVAEKAWSLYLLGAQRNQHLKMKEQEDSFSPELAEGSEFHSTFLHMLRQDLSTEGQARVRQSHHLYIDTVQRLLCATRVLTYS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JUM9-1", "uniprot_id": "A8JUM9_DROME", "id": "A8JUM9-1", "name": "Axonemal 84 kDa protein", "aln": "-----MLSLPPKKKLSKKEKARLEAEQAELMRIEMEKEKLKKLEEARQRKKLEMEQAKHRQQQEVAENRQRRSQLKDSMLFFDAVRTAIEAIKDGERHERDWEKFMRCNGLPNAASPSDLRKYIHQWHTDIAKRHLESRNWLLRTDERTLLTQDAQVPDLTRISLRQQQGRLGDVYAHRIKEVLGILNELDEMLPFKQKSALIAADLVKLKTEMRVFLKQHLDEFTYKTMSHIERDMEIDRPGVSKHIYSSDVFQSFVWTFSKDAQISLNPKARIGEQSSHNEIDFPTIEMQISLPPTVHLQSSALRGLWLNYDHFSDYCSSYCLKHARSANANILRQTKREWRKRKEILQAMLDDCGREIPLSELEQLTQDQHSASSQPPRERTYDVDKLYAEYEDELSKAHRRAIGPEAYGMLETDVNLRKYRIIGGVYCIDFLETPQQDKQLNARSFIRTITSANSLVHKEYYQTYKPPPPVLPGVRRLPEEIEAEMRMIEAALDKLALVTLQLPDSVIWFEPPVACRWETNVETLEMELADGMKPEVQKPHGEGDGEADGTGAVSGTAAATTATPTEATPLSTHAQPSPLKSSPRCPARMRSQKSDIGGESRQQVLREINDFDLRAIPSDVDLYGLVKDFVVPRLPQGFCVRLEQSTPVMSTGLRQRKVMFLARQAHIRLGQGKDMADDQLEIPKELQRLQLNSKPGLGAEFLDTEEPAEMFPPLCFDKLLKFRQMAPRSRGPAHLQGYLFSQLIDDMDRLWRLQLPRDQQEEIIQQISEQLSPTGSRTSEPGEKEPRETENDGDLAENMQPLSQELVDVLQPATAAAAFAYYTGISFVRDSQLPAEPEPESSAKRSNSMDSSEDDDDDVDSLVELLEGASTAANTLHDLLGPATNSDNSDSESKQKMSNVAAITQGKWSTRDVHDTKFNEDKLSIQFRTGRLGIFGFALNKYSNMPYQTWDLRPDMKNPGTIIFSFTASLISLDMTITKSGYTVNNFQGGSTQGITDMIGKTLSLSELKATLILSAVDIFPDEDAFCYTEGSCEKNYVMEMHCYACLSTLAQSHNFSWSRWNLLAGSRTAVLLVRELIEGK--KVPYYSTLLVTPLKTSIIDCTEVSASFNAVGIPGMEYYADLYQLSQAHAQPGSLEKQRTMNPVLRDNVAKILMAIRPLSLC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ::* *: :* *: * * *: :* .* :* : : : :: : * : .:* .:*:: ::: : : .*::: *:* *:. ::..:* *. . : :..: : .:.: : : : *:::: * ** : . :: .*. : : * :::* *.: ::. .. * : :.:* : . *:* * .***.: .. . : * : . . : . : . . : : :: . . . : * : ::: :* *:.: ::*: : :: . * * : . . : . .:. . *.. . : * .: * : : . :. . : * : . : : : ***:*:*:: * : . :: .. : .:.: :. . : : . : *. :: : :: :.::** : *. . * :* * :: ::.: *.**:** * : :: :. : . :. * . *. *::: : :: : . . : * : :.* :* : * *: .", "identical_positions": 74, "similar_positions": 221, "identity": "6.33%" }, { "cls_id": "homologset.agr.MGI:2444482", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08EC4-1", "uniprot_id": "CASS4_MOUSE", "id": "Q08EC4-1", "name": "Cas scaffolding protein family member 4", "aln": "MRGTSIREGAPKTLLARALYDNHADCSDELAFSRGDILTIVEQNVPESEGWWRCLLHGRQGLAPANRLQVLRETPADRPCPLLPRGPDTDLTSSGAPYQVQDLISPPPQGPVYEPMRSWVEGPSPATAQVYELPESPSSARIICEKTLSFPKQ--ALSVLPRPTRASLPTLPSQVYDVPVQRQGFSTLERLEKQQ---------FYDIPTSSQKALLHSSTSQ--GRDVTLAPTM--AFRQGGGYNPLSSPQKSERIHDTPVLLEKADVRNVSMTSFTKDSGSRAIPGSSAVHTG-----AVALSPQLGN--TVQRKNSLPEEPTYAFPTSR-DPLPSDAGGSYKVPSRFLIPRVEQQNTMPNIYDTPKAMQGVSHNAPKAMQGVSLAGKELERGREAPENSP-----WISGQTSFLSPDSDRLSVASSDSRASVVSSCSSISMDSSSGSSSEDSVKELWMDVDFAKETAVSLQHKVASSAAGLLLFVSRTWRFKDSLETNIHRIRRAADHVEESVREFLDFAQGVGGTACNLTDSYLQARIRDQLQTISSSYQTLLDAKGSLDRCNWSLEVLVTDKVQNSL-DDLERFVATARIVPEDVKRFTSIVIANGKLLFKQNCEKGE-----------MDLKCERCIRPPQRETESYQE-SSPFDRQPTTEHSFELARKNRVNVCWQQSPNLQEKGKPTMEGKSNRNPDFHGMSPPPLTSPSPSGQNTERKIHLSKHSRLYFGALFKAISVFASSLSNGQPPEVFITQSKLVITVGQKLVDTLCSETQEKDERNEILCGSSHLCGLLKDLALATKSAVIQYPSPSALSLLQSEVERLEHHSRKFRDTLE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M0F6-1", "uniprot_id": "F1M0F6_RAT", "id": "F1M0F6-1", "name": "Cas scaffolding protein family member 4", "aln": "MRGTGIREGATKTLLARALYDNHPDCSDELAFSRGDILTIVEQNVPESEGWWKCLLHGRQGLAPANRLQVLRETPVDRPCPLPPRGLDSDLTGSEAPCQVFNSFSPPTPGPVYEPMKSWVEGPSPATAQVYELPDSPSSARIICEKTLNFPKQ--ALFVLPRPTRASLPTLPSQVYDVPVQRQVSSTLERPEKQQ---------FYDIPTSSQKAVFHISTSQASGPGVTLAPTT--AFRQGGGYNPLSSPQKSDWIHDTPVSLGKADVRNASMTSFTKESCSNTIPGSSVVRIG-----AVTLSPQLGN--AVQKKSSPPEETSYAFLTPRGDSLPSDAGSSYKVPSRFLIPRVERQNTKPNIYDTPKAMQGVFQNTSKATQGVSLAGKELERGREAPENSP-----WVSRQTNFLSPDSDRLSVASSDSRASVVSSCSSLSTDSSPGSSSEDSVKELWMDLDFAKETAVALQSRVASSVAGLLLFVSRTWRFKDSLETNVNRIRGAADRVEESLREFLDFAQGVGGLACNLTDSYLQARVRDQLQTISSSYQTLLDAKGTLDRCNWSLEVLVVDKAQSSV-DDLERFVQVARVVPEDVKRFTSIVVANGKLLFKQNCERGE-----------VDWRCERCIQPPQREAESHPERSSPFHKQPAAEHSLELAKKSRGDVCGQKSPNLQKKGKNTMEGKSNENQDFCGTSPTPLPSPSPSGQNVERKIRLSEHSRLYFGALFKAIGVFASSLSNSQPPEVFITQSKLAITIGQKLVDTLCSETQERDERNEILCGSSHLCGLLKDLALATKNAVIQYPSPSALGLLQSELEKLEYHSRKFRGTLE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQ75-1", "uniprot_id": "CASS4_HUMAN", "id": "Q9NQ75-1", "name": "Cas scaffolding protein family member 4", "aln": "MKGTGIMDCAPKALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQ--AILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQ---------LYDIPASPKKAGLHPPDSQASGQGVPLISVT--TLRRGG-YSTLPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPSYGFLVPR-GTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATS-----------SVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSP-DDLERFVMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQ----LTPNAEFKCEKYIQPPQRETESHQK-STPSTKQREDEHSSELLKKNRANICGQ--------------------------NPGPLIPQPSSQQTPERKPRLSEHCRLYFGALFKAISAFHGSLSSSQP-AEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRGTLG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5S9-1", "uniprot_id": "A0ACD6B5S9_DANRE", "id": "A0ACD6B5S9-1", "name": "", "aln": "----------METLFARALYANTAETEDELAFCKGEIILVLEKNVVGSTGWWKCALRGRQGLAPANRLAPLSPAEAEQIAAERDCSTNHSHQS---IYQTPIALSKSPETPIYEDMNTIYKVPPQGVCSPNKQED-PEGTRPLHDGLSAHPKTGADIYDVPNLLRKSCLFTASPLHPSETSLMSSAEFHSRNEATNMLQMLQNVRCETATNHKATTLPPFGTQDPNYDFPVPSITEDSKKPRCGYSTMPNPCKSEWIYDVPVFPQKQGCEPGYCDTLPPKDIDSTTALYDILPAR--------IWPEKKH-CPIQPLYDVPK-PSISLTQSCTVNEYSPISSIYDVPPCFRQTKTTAE--QPRKQSPPEMDSKNGQEPLEYRGKPGPLYDQLHRWPSRGRTPFRQPLESTVRRDNEGTRDHQRSSTVSTSSTASSSSRSSCDSFMLS--SPEPEPLREITLSQEEAGNKLLELKEAVCQSVPKLMLFVSSQWRSREHLGQHLDQIRTASEDVTDSIDSFLNFTLDVRGNAQRLTDSNLQTRLLKQLSIVEDSGLILQQAASALRDQGWHLDVLAQDAGHSQMPDHLERFVMVARTVPEDVKRLVSMLNANGKLLFRVQVKELEVMENEGSSEGTNHKKCEPMVDSGIDESDYVQLQTTAEIEQEPKPTKSSIKSKRNSDSLKKQVS-------------------------KPQSGSPCNPIQTSRKCPISDHCRLYFGAIQKAISVFISSLNENKPPEQFISHSKLVIMVGQRLVNTLCREAKSREAGEEMLSMSNQLCAQLKQLALVTKKAALNFPDKLAVQEAHDIAKELAQRAQHFRTSLDV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*:***** * .: .*****.:*:*: ::*::* * ***:* *:*********** * . .:: .. . : . *. .. *:** *.: : * ... : : * .:* : : .** : :*. * * .* :: .. :. :: : .:. : : : :* . ...: . : : *..:..* **: *:*.** * . . ::. .. : . . : *: : .:* . *: .: .: . . *.**. * .:. : *. . *: . . .:*.: . ... : . : : :* * *:.* ** * .* * * *.. :. :*: :. : * :. : *: * .*.. *:**** ** :: * ::. *: ::: : :*: .**:*: .* * * .**** ** *: .*:. :..* * :: :* .* *:**. * :.. *.***** .** :***:**:.*:: ***:***: : :. * . :** : . *:: ::. .* . .: * . : : * . . .** :*.*.******: ***..* .**...:* :*::***.* :**:**:*** *::.:: :*:* *.:**. **::**.**.*.: :*. *: : :.* ::::** :* ", "identical_positions": 191, "similar_positions": 255, "identity": "22.58%" }, { "cls_id": "homologset.agr.MGI:2444484", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5GF25-1", "uniprot_id": "MANEA_RAT", "id": "Q5GF25-1", "name": "Glycoprotein endo-alpha-1,2-mannosidase", "aln": "-----MAKFRRRTCIILSLFIVFIFSLMMGLKMLWPNAASFGPPFGLDLLPELRPPNTHLENKADFQRSDRIDMETNTKDLKGAGVTVH----PPRASEVNLEELPPLNYFVHAFYYSWYGNPQFDGKYVHWNHPVLEHWDPRIAKNYPQGRHS---------PPDDIGSSFYPELGSYSSRDPSVIETHMKQMRSASIGVLALSWYPPDASDENGEATDYLVPTILDKAHKYNLKVTFHIEPYSNRDDQNMHQNVKYIIDKYGNHPAFYRYKTRMGHSLPMFYIYDSYITKPKTWANLLTPSGSQSVRGSP--YDGLFIALLVEEKHKYDILQSGFDGIYTYFATNGFTYGSSHQNWNKLKSFCEKNNMIFIPSVGPGYIDTSIRPWNTQNTRNRINGKYYEVGLSAALQTQPSLISITSFNEWHEGTQIEKAVPKRTANTVYLDYRPHKPSLYLEITRKWSEKYSKERMTYALDQQLPAS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NXH2-1", "uniprot_id": "MANEA_MOUSE", "id": "Q6NXH2-1", "name": "Glycoprotein endo-alpha-1,2-mannosidase", "aln": "-----MAKFRRRTCILLSLFILFIFSLMMGLKMLWPNAASFGPPFGLDLLPELHPLNAHSGNKADFQRSDRINMETNTKALKGAGMTVL----PAKASEVNLEELPPLNYFLHAFYYSWYGNPQFDGKYIHWNHPVLEHWDPRIAKNYPQGQHS---------PPDDIGSSFYPELGSYSSRDPSVIETHMKQMRSASIGVLALSWYPPDSRDDNGEATDHLVPTILDKAHKYNLKVTFHIEPYSNRDDQNMHQNIKYIIDKYGNHPAFYRYKTRTGHSLPMFYVYDSYITKPTIWANLLTPSGSQSVRSSP--YDGLFIALLVEEKHKNDILQSGFDGIYTYFATNGFTYGSSHQNWNNLKSFCEKNNLMFIPSVGPGYIDTSIRPWNTQNTRNRVNGKYYEVGLSAALQTHPSLISITSFNEWHEGTQIEKAVPKRTANTIYLDYRPHKPSLYLELTRKWSEKFSKERMTYALDQQQPAS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SRI9-1", "uniprot_id": "MANEA_HUMAN", "id": "Q5SRI9-1", "name": "Glycoprotein endo-alpha-1,2-mannosidase", "aln": "-----MAKFRRRTCIILALFILFIFSLMMGLKMLRPNTATFGAPFGLDLLPELHQRTIHLGKNFDFQKSDRINSETNTKNLKSVEITMK----PSKASELNLDELPPLNNYLHVFYYSWYGNPQFDGKYIHWNHPVLEHWDPRIAKNYPQGRHN---------PPDDIGSSFYPELGSYSSRDPSVIETHMRQMRSASIGVLALSWYPPDVNDENGEPTDNLVPTILDKAHKYNLKVTFHIEPYSNRDDQNMYKNVKYIIDKYGNHPAFYRYKTKTGNALPMFYVYDSYITKPEKWANLLTTSGSRSIRNSP--YDGLFIALLVEEKHKYDILQSGFDGIYTYFATNGFTYGSSHQNWASLKLFCDKYNLIFIPSVGPGYIDTSIRPWNTQNTRNRINGKYYEIGLSAALQTRPSLISITSFNEWHEGTQIEKAVPKRTSNTVYLDYRPHKPGLYLELTRKWSEKYSKERATYALDRQLPVS------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EYY9-1", "uniprot_id": "E7EYY9_DANRE", "id": "E7EYY9-1", "name": "Glycoprotein endo-alpha-1,2-mannosidase", "aln": "-----MARFRRKSCCAVIVLALAVFIITVILKSLSPEDNISGSHFAVKLIP--------------FPK-ENTNLILSPK--PVLMIPLE----KPEKMENELQDFPEPNYNVHAFYYVWYGSPQFDGKYVHWDHPLLPHWDPKVASSYSTGRHQ---------PPEDIGANFYPALGPYSSRDPAVLEEHMRQLRMAAVGVLAVSWYPRSMKDDNGEEIDSLLPLILDAADKNQLKVVFHIEPYKGRDDANMRENIQYIVDRYGNHPAFYKYKTSTGKLLPLYYIYDSYLQTPDVWAQLLKPNGISTVRNTP--YDGIFIALLVEERHKKDILTAGFDGLYTYFATNGFTYGSSHHNWRTIKTFCDYNDLVFIPSVGPGYIDTSIRPWNAQNTRNRINGKYYETAFNAAVDARPQIISITSFNEWHEGTQIEKAIPKTWGKTVYLDYLPHKPTVYLEITQRWARKFSDEQKKWLE-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMQ2-1", "uniprot_id": "Q9VMQ2_DROME", "id": "Q9VMQ2-1", "name": "Glycoprotein endo-alpha-1,2-mannosidase", "aln": "MLLKKYVKTRRKLKILLLLAIVALLVITIIVLGSSGRNAAIELLLDERFIARAYRPGDQPQVAEKPPPVAVALLQPQRENGVIVPEKYDEQKIKERIIQSKIDLMKQQQQRDHEAEQSSRTTLDVVISAVHIFYTAPVPWYKSKKPPPPPAEHPNDVPLTTPRPVRILNTAFYPALGLYKPSG-SLLAQHFENIRSCGIGVLILSFS------GGKPAEAALLHQILELAPQHNLSVTFELSVAGNQSVEFVRQQLQEIATYTSLAGFYKVWSQSRGVSLPVLYVSNAYKLSDSLGRLLCRSPSLVEPDGLRRILDALFIGHIRLKSHADVLRRLCFDGFYSKLPSNGAVFASTWKNWSYLKSFALSYKMLFVPTVGPGFAERNKFPRHGDIQRHRSNGRYYGVAWRTAILNHVGFINIASYNNWPDGSQIEEVMPRAG----FLDYNPGSRTKYLDLTAHWVGNFLKTRQEAAAAASPASPPNCYELLNGTIC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: **: : : : :: : : : . : ::. . : . : ::: : : * . :. . :* :. * . ..* * :.: *** ** *.. . ::: *:.::* ..:*** :*: . *: **: * : :*.*.*.:. .:. : :::: * . : :. * **: *: ::* . * . . . *.:**. : : * : ***:*: :.:** .:.*: :** :* *. .::*:*:****: : . * : : *:* **:** . :*: : :*.*:*:*:* :*:***:.:*: :*** * . **::* :* :: . : ", "identical_positions": 80, "similar_positions": 137, "identity": "16.19%" }, { "cls_id": "homologset.agr.MGI:2444486", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AAW1-1", "uniprot_id": "A0A8I6AAW1_RAT", "id": "A0A8I6AAW1-1", "name": "threonine--tRNA ligase", "aln": "MAAQALAAQAVASRLQRQEEDIRWLCAEVQRLRDEQLRGPERGQAEGPRLTREVAQLQAENRDLHQRLCDLRLRLAEQGG----------PGARRAAAHEPPTQNQEKDTKRKRLKDSEPNREVK-QPNFIKERLQLFETLKTDHQLLPATQEKK-NTNNVISVRVAGGKTVQGEEWKTTPYQVAAGISKELAENTVIAKVNGVLWDLDRPLEGDS----TVELLMFDNEEAQAVYWHSSAHVLGEAMELYYGGHLCYGPPIENGFYYDMFIGD----------RVVSSTELSALENICKTIIKEKQPFERLEVSKDSLLEMFKYNKFKCRILKEKVDTP-TTTVYRCGPLIDLCKGPHVRHTGKIKAIKIFKNSSTYWEGNPEMETLQRVYGISFPDSKMMRDWEKFQEEARSRDHRKIGKEQELFFFHDLSPGSCFFLPRGAFIYNTLMDFIREEYHKRNFTEVLSPNMYNSKLWETSGHWQHYSNNMFTFDIEKDTFALKPMNCPGHCLMFAHRPRSWREMPVRFADFGVLHRNELSGTLTGLTRVRRFQQDDAHIFCMVEQIEEEIKGCLHFLQSVYSTFGFSFQLNLSTRPEHFLGETEIWDEAERQLQNSLTGFGKPWKINPGDGAFYGPKIDIKIKDAIGRYHQCATIQLDFQLPIRFNLTYVSK--DGDDKNRPVIIHRAILGSVERMIAILSENYGGKWPLWLSPRQVMIIPVGPACENYALQVSKECFEEGFMADVDLDDSCTLNKKIRNAQLAQYNFILVVGEKEKLNNSVNVRTRDNK----IHGEISITSVIEKLKNLKKSRTLNAEEEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLY2-1", "uniprot_id": "SYTC2_MOUSE", "id": "Q8BLY2-1", "name": "Threonine--tRNA ligase 2, cytoplasmic", "aln": "MAAQALAAQAVASRLQRQEEDIRWLCAEVQRLRDEQLRGPERGQAEGPRLTREVAQLQAENRDLHQRLCGLRLRLAEQRR----------TEAGRAAAHEPPTQNQEKDTKKKRLKQSEPGREVK-QPNFIKERLQLFETLKTDHQLLPATQEKK-NTNNVISVRVAGGKTVQGERWKTTPYQVAAGISKELAEHTVIAKVNGVLWDLDRPLEGDS----TVELLMFDNEEAQAVYWHSSAHILGEAMELYYGGHLCYGPPIENGFYYDMFIED----------RVVSSTELSALENICKTIIKEKQPFERLEVSKDTLLEMFKYNKFKCRILKEKVDTP-TTTVYRCGPLIDLCKGPHVRHTGKIKAIKIFKNSSTYWEGNPEMETLQRIYGISFPDSKMMKDWEKFQEEAKSRDHRKIGKEQELFFFHDLSPGSCFFLPRGAFIYNALMDFIREEYHKRNFTEVLSPNMYNSKLWETSGHWQHYSNNMFTFDVEKDTFALKPMNCPGHCLMFAHRPRSWREMPVRFADFGVLHRNELSGTLSGLTRVRRFQQDDAHIFCMVEQIEEEIKGCLHFLQSVYSTFGFSFQLNLSTRPEHFLGEIEIWDEAERQLQNSLVEFGKPWKINPGDGAFYGPKIDIKIKDAIGRYHQCATIQLDFQLPIRFNLTYVSK--DGDDKNRPVIIHRAILGSVERMIAILSENYGGKWPLWLSPRQVMVIPVGPACENYALQVSKECFEEGFMADVDLDDSCTLNKKIRNAQLAQYNFILVVGEKEKINNAVNVRTRDNK----IHGEISIASVIEKLKNLKKSRTLNAEEDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2RTX5-1", "uniprot_id": "SYTC2_HUMAN", "id": "A2RTX5-1", "name": "Threonine--tRNA ligase 2, cytoplasmic", "aln": "MAAEALAAEAVASRLERQEEDIRWLWSEVERLRDEQLNAPYSCQAEGPCLTREVAQLRAENCDLRHRLCSLRLCLAEERSRQATLESAELEAAQEAGAQPPPSQSQDKDMKKKKMKESEADSEVKHQPIFIKERLKLFEILKKDHQLLLAIYGKKGDTSNIITVRVADGQTVQGEVWKTTPYQVAAEISQELAESTVIAKVNGELWDLDRPLEGDS----SLELLTFDNEEAQAVYWHSSAHILGEAMELYYGGHLCYGPPIENGFYYDMFIED----------RAVSSTELSALENICKAIIKEKQPFERLEVSKEILLEMFKYNKFKCRILNEKVNTA-TTTVYRCGPLIDLCKGPHVRHTGKIKTIKIFKNSSTYWEGNPEMETLQRIYGISFPDNKMMRDWEKFQEEAKNRDHRKIGKEQELFFFHDLSPGSCFFLPRGAFIYNTLTDFIREEYHKRDFTEVLSPNMYNSKLWEASGHWQHYSENMFTFEIEKDTFALKPMNCPGHCLMFAHRPRSWREMPIRFADFGVLHRNELSGTLSGLTRVRRFQQDDAHIFCTVEQIEEEIKGCLQFLQSVYSTFGFSFQLNLSTRPENFLGEIEMWNEAEKQLQNSLMDFGEPWKMNPGDGAFYGPKIDIKIKDAIGRYHQCATIQLDFQLPIRFNLTYVSK--DGDDKKRPVIIHRAILGSVERMIAILSENYGGKWPFWLSPRQVMVIPVGPTCEKYALQVSSEFFEEGFMADVDLDHSCTLNKKIRNAQLAQYNFILVVGEKEKIDNAVNVRTRDNK----IHGEILVTSAIDKLKNLRKTRTLNAEEAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VKB0-1", "uniprot_id": "Q9VKB0_DROME", "id": "Q9VKB0-1", "name": "threonine--tRNA ligase", "aln": "MLKLAPQGGRYYSQISR---ICQWILPKIQ----TQSKPPKQQQQQQPQLK-----------------------------------------EQQQHSYATLAAKMKKEKKEKPSGGGDTRKELSPLPKYIEERNVFWEKCKAEYEAELAAKKRE-----PIKVTLPDGKQVDATSWETTPYEVARGISQGLADNTVISKVNGEVWDLDRVLEGNC----TLQLLKFDDPEAQAVFWHSSAHIMGEAMERIYGGHLCYGPPIENGFYYDMHLEG----------EGISTNDYGAMEGLVKQIVKEKQNFERLEMKKSDLLEMFKYNEFKVRILNEKVTTD-RTTVYKCGSLIDLCRGPHVRHTGKVKALKITKNSSTYWEGKADAETLQRVYGISFPDPKQLKEWEKLQEEAAKRDHRKIGREQELFFFHELSPGSCFFQPRGAHIYNTLMGFIKAEYRKRGFQEVISPNIYNAKLWMTSGHWQHYAENMFSFEAEKEKFALKPMNCPGHCLIFDNRNRSWRELPLRMADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAPEQIKSEMKGCLEFLKYVYTIFGFSFQLVLSTRPDNYLGELEQWNDAEKALAESLNEFGMPWKENPGDGAFYGPKIDITIMDALKRAHQCATIQLDFQLPIRFNLSYIAD--DGE-KKRPVIIHRAILGSVERMIAILTENFAGKWPFWLSPRQVMVVPVGPAYDQYAQSVRDQLHDAGFMSEADCDAGDTMNKKIRNAQLAQFNFILVVGDKERSSNTVNVRTRDNK----VHGEVSVAELITKLQKIR-DEFIANEDSF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04801-1", "uniprot_id": "SYTC_YEAST", "id": "P04801-1", "name": "Threonine--tRNA ligase, cytoplasmic", "aln": "------------------------------------MSASEAGVTEQ----------------------------------------------VKKLSVKDSSNDAVKPNKKENKKSKQQSLYLDPEPTFIEERIEMFDRLQKEYNDKVASMPRV-----PLKIVLKDGAVKEATSWETTPMDIAKGISKSLADRLCISKVNGQLWDLDRPFEGEANEEIKLELLDFESDEGKKVFWHSSAHVLGESCECHLGAHICLGPPTDDGFFYEMAVRDSMKDISESPERTVSQADFPGLEGVAKNVIKQKQKFERLVMSKEDLLKMFHYSKYKTYLVQTKVPDGGATTVYRCGKLIDLCVGPHIPHTGRIKAFKLLKNSSCYFLGDATNDSLQRVYGISFPDKKLMDAHLKFLAEASMRDHRKIGKEQELFLFNEMSPGSCFWLPHGTRIYNTLVDLLRTEYRKRGYEEVITPNMYNSKLWETSGHWANYKENMFTFEVEKETFGLKPMNCPGHCLMFKSRERSYRELPWRVADFGVIHRNEFSGALSGLTRVRRFQQDDAHIFCTHDQIESEIENIFNFLQYIYGVFGFEFKMELSTRPEKYVGKIETWDAAESKLESALKKWGGNWEINAGDGAFYGPKIDIMISDALRRWHQCATIQLDFQLPNRFELEFKSKDQDSESYERPVMIHRAILGSVERMTAILTEHFAGKWPFWLSPRQVLVVPVGVKYQGYAEDVRNKLHDAGFYADVDLTG-NTLQKKVRNGQMLKYNFIFIVGEQEMNEKSVNIRNRDVMEQQGKNATVSVEEVLKQLRNLKDEKRGDNVLA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : : . * *.: : :. * :*:** ::: : ::: * : :.: : .* :. *:*** ::* **: **: *:**** :***** :**:. .::** *:. *.: *:******::**: * *.*:* *** ::**:*:* : . . :* : .:*.: * ::*:** **** :.*. **:**:*.::* ::: ** ****:** ***** ***: ***::*::*: **** *: *.. ::***:******* * : *: ** *******:*****:*:::******: *:*: ***:* .::: **:**.: **::**:**:*** :**** :* :***:*: **:.*.***********:* * **:**:* *.*****:****:**:*:***************** :**:.*::. :.**: :* ***.*:: *****::::*: * *: ** * .:* :* *: *.************ * **: * ************* **:* : :. *.: :***:************ ***:*::.****:*******:::*** : ** .* .: .: ** ::.* *::**:**.*: ::***::**::* .::**:*.** :. : : . : :*:::: . ", "identical_positions": 324, "similar_positions": 207, "identity": "39.37%" }, { "cls_id": "homologset.agr.MGI:2444487", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q811F1-1", "uniprot_id": "ZBT41_MOUSE", "id": "Q811F1-1", "name": "Zinc finger and BTB domain-containing protein 41", "aln": "MKKRRKVTSNLDEKIHLGYHKDSSEENAAVECGQVTYTQAPERPTPEAAQRCQELPPSPDQRKLLSSLQYNKNLLKYLNDDRQKQPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNPSTDVVTLDHVTHSVFQHLLEFLYTSEFFVYKYEIPLVLEAAKFLDIIDAVKLLNNENVAAFQAELTEKSSPEETLNELTGRLSSSHQCKFCSRHFCYKKSLENHLAKTHRSLLLGKKHGLKMLERSFSTRRSKRNRKCPVKFEDTSDD----------EQESGDGSDNLHQESSEKERSDRNDSEDPGSEYNAEDEE----LEEEVSDEDSDTE-QSDKD-NDAEEEPE-------------AGDSAGSIHEGLAPVIIQNSNKKILQCPKCDKTFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNLTVHRKKHSNEVEFHRKEHKCPYCNKLHASKKTLAKHVKRFHPENAQEFISIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECDECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCDVCKKIFKGKSSLEMHFRTHSGEKPYKCQICNQSFRIKKTLTKHLVIHSDARPFNCQHCNATFKRKDKLKYHIDHVHGIKSPDDSLSTSEEKLMSLPMEYSSDDKIFQAETKQYLDQPKVYQSEAKTMLQNVSAEVCVPVTLVPVQMPDTSSDLVPHTTTLPTSSHEMLPPQPQSTDYPRAADLAFLEKYTLTPQPANIVHPVRPEQMLDPREPSYLGTLLGLDSTAAVQNMCSSEHRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SVQ8-1", "uniprot_id": "ZBT41_HUMAN", "id": "Q5SVQ8-1", "name": "Zinc finger and BTB domain-containing protein 41", "aln": "MKKRRKVTSNL-EKIHLGYHKDSSEGNVAVECDQVTYTHSAGRPTPEALHCYQELPPSPDQRKLLSSLQYNKNLLKYLNDDRQKQPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNPSTDVVTLDHVTHSVFQHLLEFLYTSEFFVYKYEIPLVLEAAKFLDIIDAVKLLNNENVAPFHSELTEKSSPEETLNELTGRLSNNHQCKFCSRHFCYKKSLENHLAKTHRSLLLGKKHGLKMLERSFSARRSKRNRKCPVKFDDTSDD----------EQESGDGSDNLNQENFDKEKSDRNDSEDPGSEYNAEEDE----LEEEMSDEYSDIEEQSEKDHNDAEEEPE-------------AGDSVGNVHEGLTPVVIQNSNKKILQCPKCDKTFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNLTVHRKKHSNETEFHKKEHKCPYCNKLHASKKTLAKHVKRFHPENAQEFISIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECDECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCDVCKKIFKGKSSLEMHFRTHSGEKPYKCQICNQSFRIKKTLTKHLVIHSDARPFNCQHCNATFKRKDKLKYHIDHVHEIKSPDDPLSTSEEKLVSLPVEYSSDDKIFQTETKQYMDQPKVYQSEAKTMLQNVSAEVCVPVTLVPVQMPDTPSDLVRHTTTLPPSSHEILSPQPQSTDYPRAADLAFLEKYTLTPQPANIVHPVRPEQMLDPREQSYLGTLLGLDSTTGVQNISTNEHHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6PFI6-1", "uniprot_id": "F6PFI6_DANRE", "id": "F6PFI6-1", "name": "Zinc finger and BTB domain-containing protein 41", "aln": "MKKKLNP-------------KETQETTTACNS------------KRDVGMTIKDFS---LEKKCLRISQNDGCFLKFLNEDRHKLSSFCDTTVTVSGRIYHAHKVVLAFGSGYFHSRFSENPELHHVSIDNMEGSTFGHLLNFLYTSEFEVSECQIPALAEAACFLDMMEAVNILAKWAAPANADEESE--VPEEIPNFQNIQTSSGTKCLFCSRTFNYKKSLENHLAKTHSTGCHNEEEQTVVSTSVVTIRRSARQRRVPAKFKSQDSENECVVSAKPNQKIANHNSVTYEEEEEDNESKEENENEQIQQESWKEGQEETFVALEVEAAEYEDCEKPKEACVSEAQKETEPAFSHALEEHNQKTEVSSHIFPEGLAPVVIHSTNKKSLKCPKCDKIFDRKGKYESHTRVHTGEKPFQCDICLQCYSTKSNLTVHKKKHDSGTPVQRKEHKCPFCNKLHASKKTLSRHVKRFHPDHLQEFLTQKK-KSEVWKCDICHKSFSRRPHLEEHMILHSQDKPFKCAYCDDYFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNRKRHIECTHGGKRKWTCFLCGKSVRERTTLREHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHEDKRYECEECGKTFIRHDHLKKHKKIHTGEKAHQCEECGKCFRRADHLTVHYKSIHLGEKIWQRYKAVVHQCQVCKKEFRGKTNLMSHFRTHSGEKPHKCVICNQTFSIKKTLTKHMVIHSDVRPFNCPHCSATFKRKDKLKYHVDHVHSVRLLDQQQNQP----------ASPANKLIDPSLSNKNSKP--CQNASKTVLQSVAADVCVPVTLIPVQMTEEA-DLAVHG--VPHGILPALS-QPQ-QSYQSATDLVFLEKYTLTPQPTNIVHPVRVEQMLDPREQSYLGTLLGLDSATPVQNTSSAEHTQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: : *::.* ..* :. . :. :::. ::* * * : :**:**:**:* .**** : *.*: : *****:*.**.***: :*:**. . *::*:: *.* ***:******* * : :** : *** ***:::**::* : ... * :* *** * . : *.. :* **** * ************* : .::. : .: *** *:*: *.**.. ..: :: :...* . .:*. ::* .:.*:.*: .* * :* * : * .* * .: .:*::*.* : * . ***:**:*:.:*** *:****** *** ****************:**** * **********:***.. . .::******:***********::*******:: ***:: ** *** ******:***:********************:**:::********************************* *****************:***********:***********************************:******:************.******:************** * *********:*****:**:***..***:**** *:**:.* **********:** ****:* ********:*****.***** **.************:**** :: *: . . *. :*:::.. .: .:* *. :**:**.*:*:*******:****.: . **. * :* . *. *** .* *:**.***********:******* ******** ***********:: *** .: ** .", "identical_positions": 522, "similar_positions": 194, "identity": "55.71%" }, { "cls_id": "homologset.agr.MGI:2444488", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LFP4-1", "uniprot_id": "A0ABK0LFP4_RAT", "id": "A0ABK0LFP4-1", "name": "", "aln": "MLNFWAPPKHTRRLFQALDLCLFPNNNLTHAPTYFPHLLRLSADILSTKKHSLLFNAHQHPAPPAPASWMKKSMPGGMTPLKKPRNPTKLPLTLNPTKSKDVLAVLAERNQAIVPVGAWVEPASPNWSGIPAHTSAYILEEEIKEQQRRKQESLRHFQRQVKHRVNQQAKLRKKQQLDKSYKAAEKEGSIAIRYSDSAHLTSKRTSVFPRNLNAAVGSFRLPTSLVLGNATDDAENQNQLFEQQAQALSQTMKQARHQLASFKTVSEKKTSVFLNGGKKSSPTQEDLGCGK---------------------------------------------ISSVVVSEER--DNLFESCQQD---LLSEDKEKALSKVQKVKFKNPLSVVIKEDEGKQLYPHSLQPVLPEAQGYFVEVKSCLPESQSDVIDVQAVEPKASRIEPKEPGGEPDTQAAGMEFQTTE----------------------------PDGQAVKTEIQDTLKVQTVELDGD---------------------------TELEAQDSLPSHQAFLSRD-------QDFLLNCQYQGSLPKD-------HCVLPNYQNVLPKYQDQHFLPVAQEFLPTNQLALPKEQNHPLKCQKQDLPPEDQFPLPRHQYILPIYQDR-----------RDPHVLPKCQDHD-------VLSKAQNYLHSYQEQDLPLQSQ---------------------------------------------------------------SQQPSVRTAERWQEDLYLSGHECLPPRQRRDTCSRRQQ------------------------LCEEYRSGPSTEQQALLPFQSGVDQEEDKKERQKQYLRHRRIFMDIEREQVKEQNRQREQKRRAEKIKKRKEQERYAEEQRLLRVNCPEEPCSEENISDVLAQLQLQEIKGAREKQQQREKEYVRYVEALRAQVQEKMKLYNITLPPLCCCGPDFWDAHPDTCANNCIFYKNYRAYNRALHSVINSSDISEGNATLRNAIRNFASAHRRNFKTKSPVRG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C9M2-1", "uniprot_id": "CCD15_MOUSE", "id": "Q8C9M2-1", "name": "Coiled-coil domain-containing protein 15", "aln": "-------------------------------------------------------------------------MPGGMAPLKKPRNPTKLPLALNPTKSKDVLAVLAERNQAIIPVGAWVEPASPNWSGIPAHTSAYVVEEEIKEQQRRKQESLRHFQRQVRHRVNQRVKLRKKQQLHKSYKAAEKEGSIAMQYSDLAHLSSKRTSVFPSNLNAAVGRFRLPTSQVLGDAIEDGENQ--LFQQQAQALSQTMKQARHQLASFKTVSEKKTPVLPNGGRKGCPTQEGLGCGK---------------------------------------------ISFVAVSEER--DALFVSCQQD---FLSEDKEKAFSKVQKVKFKNPLSVVIKEDERKQLHPHSLQAVLPEAQDYFVEVQSGLPESQSDVIDVQNVEPKASRIEPKTLGVEPDTQATGVECQTTE----------------------------PEGQAVKTGIQDVPKVQTVELDGN---------------------------TELEAQDFLPSHQAFLSRD-------TDCLPNCQYQDSLPKG-------HCVLPNYWNVLPKYQNQHFLPVDQEFLPRNQLALPKEQNHPLQCQKQDLLPREQFPL------LLRHQDQ-----------REPHVLPKCQEHD-------VLSKAQNYLHNYQEQDLQLQNQEVNSKEPLSDITDGKGREIFSLDMFSKKPSTFMRRERGDEELPLDSPQCAPPQIQDQVFLREQSQQPSVRTAERWQEDLYLSGHECLPPRQRRDTCSRQQQ------------------------VYEEYRSGLSTEQQALLAFQSGVDQEEDKKERQKQYLRHRRLFMDIEREQVKEQNRQRERKRRIEKIKKKKEQQRYAEEQRLLRMNCHEEPYSEEKISDVLAQLQLEEIKGAREKQQQREKEYIRYVEALRAQVQEKMKLYNITLPPLCCCGPDFWDAHPDTCANNCIFYKNYRAYNRALHSVINSSDISEGNATLRNAIRNFASAHRRTPKQSLH---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0P6D6-1", "uniprot_id": "CCD15_HUMAN", "id": "Q0P6D6-1", "name": "Coiled-coil domain-containing protein 15", "aln": "-------------------------------------------------------------------------MLGSMAR-KKPRNTSRLPLALNPLKSKDVLAVLAERNEAIVPVGAWVEPASPGSSEIPAYTSAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQSS-ATHLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQARHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLLAAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPDTQAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQALLTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDD-----------------------IKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQ-REKEYLRYVEALRAQIQEKMQLYNITLPPLCCCGPDFWDAHPDTCANNCIFYKNHRAYTRALHSFINSCDVPGGNSTLRVAIHNFASAHRRTLKNL-----", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *.*: *****.::***:*** *************:**:***********. * ***:****::***:*** *:***:*:***:**::****: :*******.***: *:******:: * :**:******** ***.*:* ***.* : *:. :* *** **:*******:*******:******* :** .*: :.*:*. *:* : . * * *::*: : ** *** : ****:*.:*:********** *:::*:* ***: ..** :*****.**:*.:. * *:*.*: .:* *:*.:. :* * **: ** * *. : * .**: * **. : * : .: : *: **..* ***** * * : * *. ***. : ***: *:*****.*.*** *:**. :* .***: * :**.**: *.:* * * **: :: ::** **::* ***: ** * . *:**: : * .* .*. ** :*:* *. *: : *: : : ..*.*: :.*:** *** ** *.***.**:****************:************:**:*:*:: *****::**: ** ***:**:* *:* * *::*::******:****:***** *****:*********:****:*********************************:***.*****.***.*:. **:*** **:********. * ", "identical_positions": 436, "similar_positions": 175, "identity": "41.33%" }, { "cls_id": "homologset.agr.MGI:2444490", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NB59-1", "uniprot_id": "SYT14_HUMAN", "id": "Q8NB59-1", "name": "Synaptotagmin-14", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MAIEGGERTCG-VHELICIRKVSPEAVG-------------------FLSAVGVFIILMLLLFLYINKKFCFENV------------------------------------GGFP-------DLGSEYSTR--------KNSQDKIY-------------------------------------------------------------NSYMDKDEHGSSSESEDEALG----KYHEALSRTHNSR--LPLADSR-QRNYAWETRQKYSPLSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGD-SKCEFSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYG--TLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPN-------------------TYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRS-MKRKEMIGWISLGLNSSGEEELNHWTEMKES-KGQQVCRWHALLES--------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TN84-1", "uniprot_id": "SYT14_MOUSE", "id": "Q7TN84-1", "name": "Synaptotagmin-14", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MAIEGGERTCG-VHELICIRKVSPEAVG-------------------FLSAVGVFIVLMLLLFLYINKKFCFENV------------------------------------GGFP-------DLGSGYNTR--------TNSQDKMY-------------------------------------------------------------NSYMDRDEPGSSSESEDEALG----KYHEALSRTHNSR--WPLVDSR-QKSYAWETRQKYSPLSAEYDGYSTEASMEDGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGD-AKCEISHCSNSPRCSFNKCPSEGSTGHEAESYHNKGYEDDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYG--TLDVTFDYDSERQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNPSGCDSQVSLSEASCGDSTSSCQSLQHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPN-------------------TYVKLTLLNSMGQEMSKCKTSTRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNRRS-MKRKEMIGWISLGLNSSGEEELRHWTAMKES-KGQQVCRWHALLES--------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AMJ4-1", "uniprot_id": "A0A8I6AMJ4_RAT", "id": "A0A8I6AMJ4-1", "name": "", "aln": "MAFFKSFQQNLPSVSSLVDTIS----SAVEDLSTAVGEVSYAITDSVAGQVANMMHGFCPEEGSCTAEEATGSSKAQSTALQDTSTSKNTAHQKAQSDLDQKAKQTTGCNTSTPQRQEQEIYKQGLHIHEGQWATSEYQETGEAGGAAVKGLMSDGISAVKQKMRPAPTCHELEQTDKCEVSGVGNSGSDTNGLNKVSYQDVKGSLSSSGQNFLSVQKCMVTDSSKARLQHVPVGREQEKSGTVTKSKRLSDLEHSEHLEKAKSRNKHNGFKGNERSGNDHSPDDSTRNSRYRAQRSNAKEDTHSAPSTHCKNVFPRRIKEKTNPTKCDKVKGDMKAKKNEASSAKRGTAKSKVGKYSKILPEKDNSYMDRDEPGSSSESEDEALG----KYHEALSRTHNSR--WPLVDSR-QKSYTWETRQKYSPLSAEYDGYSTEASIEDGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGD-AKCEISHCSNSPRCSFNKCPSEGSTGHEAESYHNKGYEDDVPSDSTAVLSPEDMSAQGSASQLPKPFDPEPEAKYG--TLDVTFDYDSERQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNPSGCDSQVSLSEVSCGDSTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSTRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRS-MKRKEMIGWISLGLNSSGEEELRHWSAMKES-KGQQVCRWHALLES--------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6Z9M8-1", "uniprot_id": "A0A8M6Z9M8_DANRE", "id": "A0A8M6Z9M8-1", "name": "", "aln": "MAFFKSFQQSLPSVSAMLESVT----EKVDDLAFALSDVTYTVTGELAEHVNTIIHKVQAEELKRIRKKEAEEKEAAARQVQER-----------RDTFLDRAKIQTQAASGLVEDPEPQIAKN------------------------------DNCSVLSIETLSSE--SDLSQTPDMLIEKFK------------------AQNSADALSVCQQNGSCIKETSESTKAKP-----------------------------------------------SSPADGNEK------KKSSSRDAEE-------------------------------------------------------------KSYVNADYHCSSSDSDDEVIG----QYQEAVSRSQGLRGGAARTNSRHQKGYGWDTRQKYSPLAAEYDGYSSEASADDVNCIQRMRRTPPLDELQPPPYQDEDGSPRMSCTPSDLGD-AKCDLSHGSDSPRHSYGKCPSELSGAQETESFLNKGYEEDVPSDSTAVLSPEDLSARGSAAQLPKGYDPEPLAQYG--TLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIILDPYCNIPGSDSQASMSDVSCSETASSYPSAAQGSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRS-MKRKEMIGWISLGLNSSGEEELTHWTEMKES-KGQQVCRWHSLLES--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TC14-1", "uniprot_id": "A0AB32TC14_DANRE", "id": "A0AB32TC14-1", "name": "", "aln": "MAFFKSFQQNLPSVSSLLDSVSNTVSTAVDDLSTAVSDVTYTVSDQLTEQVNTIINKVQTEEDG----KSGKDAEGSSDDVQKDRKLKRQDTEADADGESRRSRKSKKNSMWTIEVDEAEIQREKERQEEARRAEEEEWEWCYAPSKGWYRKRKDPNQPSQTSDNQTSNTEQESKEVGTLEESTSLSG---------------KHKKEGDHHKENANGVHTSNSQEEQDSQE----------------------------------MSGDPDTSTSNIDRNGENCSEKIEEDEDEVSHEEGKTQK---------------------------------------------------------KKGKVFSDEEQEEAVQDSKNSKAKSKAKKNKECKDGGCAEKGSESEDETQKKHKDSHQQRSGWRNRDEENEDCSSEASAE---LVKRKKGSSSLNELQPPPYRDKDDVKRGSRGRSDSAEGSGSEISEGTEDP--------------EDTESYLNKGYEEDAPSDSTAVLGPEDS----LIPPLPESYEPEALGKYG--TLDVAFEYDPGEQRLAVTVTAATDIPTLKSTGNISWQVHLVLLPTKKQRAKTGVQKGPCPVFTETFRFSCVEEDALGDYAVRFRLYSVRRMKKEKVLGEKVFYLTKLNLQGKLALPVTLEPGTSVPGCGSVVSVSRSAG---ALSCRSTGESSIPELLLGLLYNSTTGRLSAEVIKGSHFKNSASDKLPIGLFCCVKHFISGQLYIMRDTYVKLTMLDSKGKEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSEVTLQVSVYSRRSSMKRRERVGWVALGLNSTTEEQEEHWTQMKES-EGQQVCHWHTLIDS--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KF61-1", "uniprot_id": "A0A0B4KF61_DROME", "id": "A0A0B4KF61-1", "name": "", "aln": "---------MIVTSASGLDSTPTLGTIEVTTLLGAFFGVLVLLLLLFLFISR------------------------------------------------------------------------------------------------------KCCFHYRHAINCCDERHLAVKCVQKITRKRR-------------------YENTSSDSEEDILRRLRWHQQHQLGEKP----------------------------------------------GGYGLGISQAN------PLTAQSFNYH------------------------------------------------------------QAGASADLQRVTVSRDPLAIAE---RGKVGIPSSHSECSSNDSMEVSVDSHTGVLTGLSKATTTVPHPATAFRNPCGEHRAKTQALRYQHRVNVAAPPKLDKERDNVLVVPMVNAYS------------------------INNNNNSITTSNNHPSSNNNDDEPLFDTSDLRSIKSDDLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPLGSGQTTHTQVRMLMLPSKKQKLKTKIRSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLELETNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSLSLNKAPD-------------------TYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRH-MKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVLVDSXFEQLGQSSGRSGKALRKLSLAAFKDRSREKSSKESRLEENGAQFHAAVALDIEPGLELDFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. : . . : . : . . : : : . : . . : :: .** *.. : . .: . .:.: .. .*. .::...* * : *. : * *:: : **. ::: : : .::*. **::::** ***: ** :: * * : *:* : :: : :.: .:*.***. .*::**: :** . ::.::*: : : : *:* . .* .* .: : : * * ... .*:*:** **..*****.*:****:*:. : :: * ****:.::.* *:*:*:.*** ****** :****.********.:*** :*** :* **:.* :**.:*****: .*: **: : * :*: :.:** *::* ", "identical_positions": 114, "similar_positions": 150, "identity": "12.17%" }, { "cls_id": "homologset.agr.MGI:2444491", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZV81-1", "uniprot_id": "D3ZV81_RAT", "id": "D3ZV81-1", "name": "HEAT repeat-containing protein 3", "aln": "MGKSRTKRFKRPQFSPVGSCQAEAAATANGTGDEEDDGLAAELLEKLQHPSAEVRECACAGLARLVQQRPALPDLARRDAVRRLG-PLLLDSSLAVRETAAGALRNLSACGGFDVCDDMVAKDIMTPLVALLRECSSGLDSNEMSPQEKADKKRNSIESIANEAVNVLWNVCECSSRAVSIFNKEGCLEIVLQYLRRFPTSIDLAVSVAYCLQTVTEDNPELLKSFDGTALRVLESALLCPVTSMEYILLKTLVAGTIWNLKDIIPSKSQAEIINAILNTLSEVLGVNAGDTVIQMKEAETQRLKDAAESEDILANANGDGEMEFQDDEMEEIPHKRKLRRKTFISDLLPSTDKELREAMALLTAQQTALEVIVNMCCSEDPSDDEWEELSSSDESEAFMENSFNECSGQLMSPLCLSHEIHSALTNCLIPKKVFEKTSSPNSDAVDICSKNPTWKPLIRKMSTIQCRALMCLQSLVSLLDIDHLGGAPALQTLAQHLSQLLFSQPDFAKHADFLEAISSALRALLQTMAS-KNIPQCMTPEQLMTLCREGIHSSSIGVRVNVVSILGITGSVLAKEDGTLETLKTIGCFLLEVTTKDPSLVVAGEALDALFDVFADGEEAEKASVQIKLLAALKEFQPVFKMKMRKEGRARYSPDQLCVLDNVKMNLRRFIAYQETVEKRLTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQM4-1", "uniprot_id": "HEAT3_MOUSE", "id": "Q8BQM4-1", "name": "HEAT repeat-containing protein 3", "aln": "MGKSRTKRFKRPQFSPIESCQAEAAAASNGTGDEEDDGPAAELLEKLQHPSAEVRECACAGLARLVQQRPALPDLARRDAVRRLG-PLLLDSSLAVRETAAGALRNLSACGGFDVCDDMVAKDIMTPLVALLRECLSGLDSNEMSPQEKADK-RNPVESIANEAVNVLWNVCECSGRAVSIFNKEGCLEIVLQYLRRFPTSIDLAVSVAYCLQTVTEDNPELLKSFDGTALRVLESALLCPVASMEYILLKTLVAGTIWNLKDIIPSKSQAEIINAILGALSEVLGMNTGNMVIQMKEAETQRLKTAAESEDILANANGDDLVE--DDEMEEIPHKRKLRRKTFISDLLPPTDKELREAMALLTAQQTALEVIVNMCCSEDPSDDEWEELSSSDESEAFMENSFSECSGHLMSPLCLSHEIHSALTNCLIPEKVFEKTSSPNSVAVDICSKNPTWKPLIRKMNTIQCRALMCLQSLVSLLDIDHLGGAPALQTLAQHLSQILFSQPDFAKHDDFLEAISSALRALLQTMAS-KNIPQCMTPEQLMTLCREGIHSSSIGVRVNVVSILGITGSVLAKDDGTLDTLKTIGCFLLEVATKDPSLVVTGEALDALFDVFADGEAAEKASVQIKLLAALKEFQPVFKMKIRKEGRGKYSPDQLCVLDNVKMNLRRFIAYQETVEKRLTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z4Q2-1", "uniprot_id": "HEAT3_HUMAN", "id": "Q7Z4Q2-1", "name": "HEAT repeat-containing protein 3", "aln": "MGKSRTKRFKRPQFSPTGDCQAEAAAAANGTGGEEDDGPAAELLEKLQHPSAEVRECACAGLARLVQQRPALPGLARRDAVRRLG-PLLLDPSLAVRETAAGALRNLSACGGFEVCDDMVTKDIMTPLVALLKECSAGLDSNEMSLQEKKDQNRNSIENIANETVNVLWNICECSSRAVSIFNKEGCLEIVLKYLSRFPTNVDLAISVAYCLQTVTEDNPELLKSFSATALNMLESALLSPVSSMESLLLKTLVAGTIWNLKDIIPCKSQAEIINALLKILSEVLGMDAGEMVIQMKEAETQRLKTAAEAEEILENTNGDDLIE--DDEMEGISHKRRVRRKTFVSDLLPPTDKELRETIALLTAQQTALEIIVNMCCNEDPSDDEWEELSSSDESDAFMENSFSECGGQLFSPLCLSHEVHTALTNYLIPKKIFEKTAFPNSIAVDLCSRNPTWKPLIRKMNTIQCRALFCLQSLVSLLDVEHLGGAAALQTLAQHLSQLLFSQPDFAKHVDFLEAISSALRALLQTMAS-KNISQCMTPDQLMTLCKAGIHSSNVGVRVNVVSILGITGSVLAKEDGTLETLKNIGCFLLEVTTKDPSLVVAGEALDALFDVFADGKEAERASIQIKLLSALKEFQPVFKMKIRKEGRGNYSTDQLCVLDNVKMNLRRFIAYQETVEKRLTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VI15-1", "uniprot_id": "Q9VI15_DROME", "id": "Q9VI15-1", "name": "SYO1-like TPR repeats domain-containing protein", "aln": "MGKVRKVKTRTP-----SGVDTSAEIDVESAGEAEGCGPIEAICVHLQQANVEEKLNGLHSFAVLALRKEKVPEIRDSELVRIAA-PLLCDKESAIRNAAAGAFRNLSVFG-TEVCDFLVENDILTALLTLVRSYDLTKGGFENELH----------ADTFQQAIHLLRNLCESSPTATEALNQANFLSSLLLGFDYRKFGLEVAISVAQLVLVVSENNSSSWNVLASS--TILPELLVAPTESHAQLYLNALAAGILCNVPACAAAHT-----REILNSLDKLLSIDP-QAQLQSCKSEILNAKSKNEAPVLEISMETEDMTETQSANQSKPNQ--------------CDAEVALKNLEHLLDAQRLVAEIITNLGSSDEQSN--WDTDSEHSESESVADYDMEDETADSGS-GGLPANFLETIKQNKVIEKLWQKAQPLQPAVENLVSQQ---ENIKEKVEKLRVSYLICLQNLCNVLPPEDLGGCSNLYNMWMILGQQAFRG---SEDVSVMEAITSLMRSSLSLLKSRKDLFGQMTENDLNMIIEGASKCTDINIRVNWNRMLGTLGSLLSEP-----LVKAIVLFLLTYCAQEDDLWALSEGLDALMDIFAVDD-WPQIIAELEMCDRVQALEELFKSKLRQQRRE--LKERRATVQTVKTNFSRFVFYLNKNCKK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07395-1", "uniprot_id": "SYO1_YEAST", "id": "Q07395-1", "name": "Synchronized import protein 1", "aln": "MGRSKKRSRASS---SRLNPLRKAGSNDNNKDTNVVNKKLQPLLQNLSSVVPNDRSIALSSISVLCEDAHMRQLLLKEKLVPIILNKLLNDSNSDIVVESFGLLRNLSLEEGYDVSIYLWRSDIWTSITSNFGRIVESLSALQAAEQQPQ---LKPAGKSKIESKRLLFDFADNLLSLVVALSNG--SDDILNEILTESKINEIFQVISQLLKYGVEKLP---INLFNTTLDLIYDLSSESFEFIDHVSNNELLSQFLNGLSPALHPQAN-----ELTKVLIEGIHCQFLDMKITYDQCNKMIHSVCHSINNIDPVQLVNDINN----------------------------PVEIGPATSKDESSKVITKIKDYNAKRNESMIKLQSIEIAIDLITAIIEIVASKYESPESQEVAIPEELINTLTN--FLPHVFMILKDTFTSRILIGWNNLIWLFVSLSLTELSGELLTTLWSYVTQLDSQDD-LSIKIGRMGCIWALLKLIFPDGAFESENRALINVQMLNNSGFARG---------------IIEEFQNNNDLELQQKCINVLSTYAMIQGQIDANKEIGQFFIQTLTQLNVRPEILIEMTNSLFQIYGDASYDYNEPIFVRGGFLSILKDQVVPNLRQQFKMVDKNK-NPELKERCHDCFTTLDSFIHYKMNENSTNQ-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: :. . . .* :. . : :*. : : . .:: * : . * ** * . : : * :**** :*. : .** *.: : . .. : : . :: .:* :..: . :.: . :* : :: :: : *. . : : :: . . : : * : : .: :: : * : : : : : :.: . . : :. : : :.: :: :: . . :. : .. . . :. :. ::.: . ::: . : .: : .: : * * . . * :. . : : . : : . . *. : . : . : ..: :: : :*. . : .: : : * .: * :.* : . : . : . . :: ::: : : . .: *: * . . ", "identical_positions": 33, "similar_positions": 181, "identity": "4.82%" }, { "cls_id": "homologset.agr.MGI:2444496", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHE0-1", "uniprot_id": "PRR11_MOUSE", "id": "Q8BHE0-1", "name": "Proline-rich protein 11", "aln": "MPKYKQRRRKLKAKAKRMSKKKEAAVVSPKLLTPSPPLPEPERVVTSAADIPQSRNWLRPSWNLRFPNIKDAINLWTNRAWCIYSCCQTCVAQSLEVLKDALFPSRVYHRELHSLKQQLCVLKRELCKLRENLKSISENSSCSSCCHKCCPSDKLTTVPACAPTTNGESQTVLSSTQPQPANHPPSPPPLPPPPPPPPPLPPPPPPLAPLLLRKSGTTKALQVEPLK--KDGPMHITVKDLLNVKLKKTQSVDERKKLVPSPPEERTPLVTVSDLQHVTLKPNSRVSATRIKNVLITPGKSQIDLRKLLRKVQVERSPGGTPLNNKENMDTGTGLTPVMTRALRRKFQLAHPQSPTQSLPLSTSSFDEQN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GJX6-1", "uniprot_id": "A0A8I6GJX6_RAT", "id": "A0A8I6GJX6-1", "name": "", "aln": "MPKFKQRRRKLRAKAKRLCKTKEASRVLPKLLAPPPPPPTPERVVTSSADIPQSRNWLRPSWNLRLPNFKAAINLWTNRAWCIYSCCQTRVAQSLEVLKDAIFPSRVYHRELHSLKQQLCVLKSELCELQENLKSISEHSSRSSCCHTCCGGDRLTTVPACAPTTHGESQTALPPTLPQPASHPPPPPPLLPLPPPPPPLPPPPPPLAPLLLRKSGSTKALQVEPLK--KDGPMHITVKDLLTVKLKKTQNIDERRKFVPSPPEERTPLVTVSDLQRITLKPNSRVLATRIKNVLITPGKSQIDLRKLLRKVEVERSPGGTPLNNKENMDTGTGLTPVMTRALRRKFQLAHPQSPTQSLPLSTSNFDEQN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96HE9-1", "uniprot_id": "PRR11_HUMAN", "id": "Q96HE9-1", "name": "Proline-rich protein 11", "aln": "MPKFKQRRRKLKAKAERLFKKKEASHFQSKLITPPPPPPSPERVGISSIDISQSRSWLTSSWNFNFPNIRDAIKLWTNRVWSIYSWCQNCITQSLEVLKDTIFPSRICHRELYSVKQQFCILESKLCKLQEALKTISESSSCPSCGQTCHMSGKLTNVPACVLITPGDSKAVLPPTLPQPASHFPPPP-------PPPPLPPPPPPLAPVLLRKPSLAKALQAGPLK--KDGPMQITVKDLLTVKLKKTQSLDEKRKLIPSP-KARNPLVTVSDLQHVTLKPNSKVLSTRVTNVLITPGKSQMDLRKLLRKVDVERSPGGTPLTNKENMETGTGLTPVMTQALRRKFQLAHPRSPTPTLPLSTSSFDEQN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAB4-1", "uniprot_id": "E7FAB4_DANRE", "id": "E7FAB4-1", "name": "", "aln": "MGGYRGLGCAYQRRRKRNGSSRRWALKSKMAPTAPDPDSKTKVVGMGEMSIQTTKRSSPLSITALLSAFR-----------SVVQKCRRTIYQTCRGFFNVFLFWRGYAERVESLHQKVDELQRELALLHSTLKLSQEAKTS-------------------------DGQWEMPDGVRPLVSPPPPPPP----PPPPPPLPPPQILVTLPPKVASFSKKTAQANSLKEKQNGPVAVTLRDLQAVQLRKVTVS---QKTLMSPEKRRSPLVTLADLQKVKLRRSNSDLPLKLRSSLRTPTKNGMSLRVPLRKVNLTRSPGGTPRCNKENNVTDSSLDPSMTKGLGNKYLNSLTKGLSPFKCA---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: : : :* ..:. : :.. * . .: * . .* :: * . :. :: .: . *: : *: . : :.:: * ..: *::*:. *: :*. *:. ** .* .: :.: :. .. *.** ******** :: . *: *. .** ::**: :*::** *:*:*. :* : ** : *.****::***::.*: .. . :: . * ** *. :.** ****:: ******* **** *.:.* * **:.* .*: : .:. : ", "identical_positions": 80, "similar_positions": 108, "identity": "21.62%" }, { "cls_id": "homologset.agr.MGI:2444505", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VIG2-1", "uniprot_id": "MARF1_RAT", "id": "Q8VIG2-1", "name": "Meiosis regulator and mRNA stability factor 1", "aln": "-MEGNGTENPCSRTLGWLHQNNDAKPWLWKFSGCFSLPEQTLPLSSQTKEYMENKKAAVELKDIPSPLHVGSKFFPAVPLPDIHSLQQPKVQLSAIPKVSCCAHCPNEPSTSPMPFGGGSGSSGRSGSLIHTGSLLDSPSTGTVTCQVGSDFAFQSVSSLQNASARNNLVGLASDLPSMCVDSNLPSCKHLSCCGKFH--FQSCRSNVHKLHQFQTLQGCTSAGYFPCSDFPSEAPGHLEEHLSHSELTPHLCTNSLHLNVAPPVCLKGSLYCEDCLNKPARNSIIDAAKIWPNIPPPSTQPAPRAVPLCNRCGTKGMEKETS-LLATSLGKAASKFGSPEVAVTGQVLETLPPIGVFWDIENCSVPSGRSATTVVQRIREKFFRGHREAEFICVCDISKENKEVIQELNNCQVTVAHINATAKNAADDKLRQSLRRFANTHTAPATVVLVSTDVNFALELSDLRHRHGFHIILVHKNQASEALLHHANQLIRFEEFISDLPPRLPLKIP-CHTLLYVYNLPANKDGKSISNRLRRLSDNCGGKVLSITGCSAILRFINQDSAERAQKRMENEDVFGNRIIVSFTPKHRECFEAKSSNAVVDKAKSPKKVKNTKLCLIKDTGEQSPSAKAMPGKGLQANSGSATKNTNFKGLQELCRMEPKSGNRIRDHQQGHGSLATLPNSGPTASVPTLKNTGVRETLHRSSQKKENLSSQSIASSPAQKKKREGTVFQISYPSAFSQLIASRQVSPLFSSQSWSPRSMSPNLLNTASPLAFNIANPSSAADCSDPFANGVDIQVSNVDYRLSRKELQQLLQEAFSKHGQVKSVELSPHTDYQLKAIVQMRNLHDAICAVNSLHRYKIGSKKILVSLSTGAANKSLSLLSTETMSILQDAPACCLPLFKFIDIYEKKYGHKLNVSDLYKLTDMIAIREQGNGRLVCLLPSNQARQSPLGSSQSHDGSSTNCSPVLFEELEYHESVCKQHCSNKDFSELVFDPDSYKVPFVVLSLKVFAPQVHSLLQTHEGTVPLLSFPDCYAAEFGDLEITQDRDKGVPLEHFITCIPGVNIATAQNGVKVVKWIHNKPPPPN------TDPWLLRSKSPVRN---------PQLIQFSREVIDLLKNQPSCILPISNFIPLYHHHFGKQCRVSDYGYSKLIELLEAVPHVLQILGMGSKRLLTLTHRAQVKRFTQDLLKLLKSQASKQVIVSDFSQAYHWCFSKDWDVTEYGVCDLIDIISEIPDT---TICLSQQDDDMVICIRKRERTQDEIERTKQFSKDVVDLLRHQPHFRMPFNKFIPSYHHHFGRQCKLAYYGFTKLLELLEAIPEILQVLECGEE-KILTLTEVERFKALAAQFVKLLRSQKGN---CLMMTDLFTEYAKTFGYTFRLQDYDVSSVSALTQKLCHVVKVADMESGKQIQLITRKSLRPLTVQLLVVLMSWEGDAYLPVDELKRHYETTHSTPLNPCEYGFMT-----------LTELLKSLPSLVEVFMNDKAEECVKLTSLYLFAKNVRSLLH--------------------TYHYQQIFLHEFAMAYTKYVGETLQPKTYGYSSVEELLGAIPQVVWIKGHGHKRIVVLKNDMKNRLSSFDLSPVNHEDQPA---------------------VSRQILEVPEPHLASELHLRT---GPSQMEQELLQLANSSPVDLLCAPVPSCLPSPQLRPDPVILQPTDLIQFEE------HPQEPLGVLFLNQEEKTEIPIPVKKGNLSCNSSPSSP-ASASAPPKPSSEAPGLLISKDA------------------------VESPAKKQPKNRVKLAANFSFAPVTKL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJ34-1", "uniprot_id": "MARF1_MOUSE", "id": "Q8BJ34-1", "name": "Meiosis regulator and mRNA stability factor 1", "aln": "-MEGKGTENPCSRTLGWFHQDNDAKPWLWKFSGCFSRPEQTLPLSSQTKEYMENKKAAVELKDIPSPLHVGSKFFPAVPLPDIRSLQQPKVQLSAIPKVSCCAHCPNEPSTSPMRFGGGSGSSGGSGSLIHTGSLLDSPSTGTVTCQVGSGFAFQSVSSLQNASTRNNLVGLSSDFPSMCVESNLPSCKHLSCCGKLH--FQSCHSNVHKLHQFQNLQGCASAGYFPCSDFPSGAPGHLEERLSHSELTPHLCTNSLHLNVAPPVCLKGSLYCEDCLNKPARNSIIDAAKIWPNIPPPSTQPAPPAIPVCNGCGTKGMEKETSLLLATSLGKTASKFGSPEVAVTGQVLETLPPIGVFWDIENCSVPSGRSATTVVQRIREKFFRGHREAEFICVCDISKENKEVIQELNNCQVTVAHINATAKNAADDKLRQSLRRFANTHTAPATVVLVSTDVNFALELSDLRHRHGFHIILVHKNQASEALLHHANQLIRFEEFISDLPPRLPLKIPQCHTLLYVYNLPANKDGKSISNRLRRLSDNCGGKVLSITGCSAILRFINQDSAERAQKRMENEDVFGNRIIVSFTPKHREFFEAKSSNAIADKVKSPKKVKNTKLCLIKDTSEQSPSVKAMPGKVLQANSGSATKTTNIKSLQELCRMESKSGNRNSDHQQGHGRLAALPNSGPTASVPIVKNTGVTEPLYRSSQKKENPSSQSTVNSPVEKKKREETVFQVSYPSAFSKLIASRQVSPLLTSQSWSPR---------ASPLAFNIANPSSGADCPDPFANGVDIQVSNVDYRLSRKELQQLLQEAFSKHGQVKSVELSPHTDYQLKAIVQMRNLHEAICAVNSLHRHKIGSKKILVSLSTGAANKSLSLLSTETMSILQDAPACCLPLFKFIDIYEKKYGHKLNVSDLYKLTDTIAIREQGNGRLVCLLPSNQARQSPLGSSQSHDGSSSNCSPVLFEELEYHEPVCKQHCSNKDFSELVFDPDSYKIPFVVLSLKVFAPQVHSLLQTHQGTVPLLSFPDCYAAEFGDLEITQDSHKGVPLEHFITCIPGVNIATAQNGVKVVKWIHNKPPPPN------TDPWLLRSKSPVRN---------PQLIQFSREVIDLLKTQPSCILPVSNFIPSYHHHFGKQCRVSDYGYSKLIELLEAVPHVLQILGMGSKRLMTLTHRAQVKRFTQDLLKLLKSQASKQVIVRDFSQAYHWCFSKDWDVTEYGVCDLIDIISEIPDT---TICLSQQDDDMVICIRKRERTQDEIERTKQFSKDVVDLLRHQPHFRMPFNKFIPSYHHHFGRQCKLAYYGFTKLLELLEAIPEILQVLECGEE-KILTLTEVERFKALAAQFVKLLRSQKGN---CLMMTDLFTEYAKTFGYTFRLQDYDVSSVSALTQKLCHVVKVADMESGKQIQLINRKSLRSLTAQLLVLLMSWEGDAYLPVDELRRHYETTHSTPLNPCEYGFMT-----------LTELLKSLPYLVEVCTNDKAEEYVKLTSLYLFAKNVRSLLH--------------------TYHYQQIFLHEFSMAYNKYVGETLQPKTYGYSSVEELLGAIPQVVWIKGHGHKRIVVLKNDMKNRLSSFDLFSVNHEDQPA---------------------VSRQILAVPESHLASELQLRTG-TGPSQMEQELLHLASSSPVDLLCAPVPSCLPSPQLRPDPVILKPADLIQFEE------HPQEPLGVLVLNQEEKSEVPLPVQKGNLSCDSSPSSP-AASPAPPGPSSEAPRPLFSKDA------------------------VESPAKKQPKNRVKLAANFSFAPVTKL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4F3-1", "uniprot_id": "MARF1_HUMAN", "id": "Q9Y4F3-1", "name": "Meiosis regulator and mRNA stability factor 1", "aln": "MMEGNGTENSCSRTRGWLQQDNDAKPWLWKFSNCFSRPEQTLPHSPQTKEYMENKKVAVELKDVPSPLHAGSKLFPAVPLPDIRSLQQPKIQLSSVPKVSCCAHCPNEPSTSPMRFGGGGGGSGGTSSLIHPGALLDSQSTRTITCQVGSGFAFQSASSLQNASARNNLAGIASDFPSMCLESNLSSCKHLPCCGKLH--FQSCHGNVHKLHQFPSLQGCTSAGYFPCSDFTSGAPGHLEEHISQSELTPHLCTNSLHLNVVPPVCLKGSLYCEDCLNKPARNSIIDAAKVWPNIPPPNTQPAPLAVPLCNGCGTKGTGKETTLLLATSLGKAASKFGSPEVAVAGQVLENLPPIGVFWDIENCSVPSGRSATAVVQRIREKFFKGHREAEFICVCDISKENKEVIQELNNCQVTVAHINATAKNAADDKLRQSLRRFANTHTAPATVVLVSTDVNFALELSDLRHRHGFHIILVHKNQASEALLHHANELIRFEEFISDLPPRLPLKMPQCHTLLYVYNLPANKDGKSVSNRLRRLSDNCGGKVLSITGCSAILRFINQDSAERAQKRMENEDVFGNRIIVSFTPKNRELCETKSSNAIADKVKSPKKLKNPKLCLIKDASEQSSSAKATPGKGSQANSGSATKNTNVKSLQELCRMESKTGHRNSEHQQGHLRLVVPTHGNSSAAVSTPKNSGVAEPVYKTSQKKENLSARSVTSSPVEKKDKEETVFQVSYPSAFSKLVASRQVSPLLASQSWSSRSMSPNLLNRASPLAFNIANSSSEADCPDPFANGADVQVSNIDYRLSRKELQQLLQEAFARHGKVKSVELSPHTDYQLKAVVQMENLQDAIGAVNSLHRYKIGSKKILVSLATGAASKSLSLLSAETMSVLQDAPACCLPLFKFTDIYEKKFGHKLNVSDLYKLTDTVAIREQGNGRLVCLLPSSQARQSPLGSSQSHDGSSTNCSPIIFEELEYHEPVCRQHCSNKDFSEHEFDPDSYKIPFVILSLKTFAPQVHSLLQTHEGTVPLLSFPDCYIAEFGDLEVVQENQGGVPLEHFITCVPGVNIATAQNGIKVVKWIHNKPPPPN------TDPWLLRSKSPVGN---------PQLIQFSREVIDLLKSQPSCVIPISHFIPSYHHHFAKQCRVSDYGYSKLIELLEAVPHVLQILGMGSKRLLTLTHRAQVKRFTQDLLKLLKSQASKQVIVREFSQAYHWCFSKDWDVTEYGVCELIDIVSEIPDT---TICLSQQDNEMVICIPKRERTQDEIERTKQFSKDVVDLLRHQPHFRMPFNKFIPSYHHHFGRQCKLAYYGFTKLLELFEAIPDTLQVLECGEE-KILTLTEVERFKALAAQFVKLLRSQKDN---CLMMTDLLTEYAKTFGYTFRLQDYDVSSISALTQKLCHVVKVADIESGRQIQLINRKSLRSLTAQLLVLLMSWEGTTHLSVEELKRHYESTHNTPLNPCEYGFMT-----------LTELLKSLPYLVEVFTNDKMEECVKLTSLYLFAKNVRSLLH--------------------TYHYQQIFLHEFSMAYTKYVGETLQPKTYGHSSVEELLGAIPQVVWIKGHGHKRIVVLKNDMKSRLSSLSLSPANHENQPS---------------------EGERILEVPESHTASELKLGADGSGPSHTEQELLRLTDDSPVDLLCAPVPSCLPSPQLRPDPVILQSADLIQFEE------RPQEPSEIMILNQEEKMEIPIPGKSKTLTSDSSSSCISAAVPVPPCPSSETSESLLSKDP------------------------VESPAKKQPKNRVKLAANFSLAPITKL---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7KWG9-1", "uniprot_id": "Q7KWG9_DROME", "id": "Q7KWG9-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MFQRHTSVIDLHRWN-----------------YPECWPFDRNGKVENIYVMEHSDPVPYQQLSTLSPTTALYSNFNNSLEAGTAERLRLNKTGSQVHSLYVGDGQVQNASEPLSFPSHLNLYQYVRTPANFTINSRNRYIPYYNNRSYSASTTGFPIAS-----------------------------------------------------------------------------------------------TPLISSHAHIQDQQGAASYQTIVPLYQTASHCAQQHTTLASVAPIVDNS-----------------------------------------------------------------------------------------------------FVESTTCPMAGITSHN-------IKMKMIPPN----------------------------------------------------------------------------------------VLLPCSRPTTTAVTIQRSTGEDGGDKEGHTFAKIT----------------------------------------------------------------------------EMSDAVTLQITNLDYSLDESHIRSFLLNQLKPITPVVSLVFEGSS----YAKVTVPDLYFAKQVVSNLHRKKIGHKRMLVSYTRDSSLTEVNTLRCQVAGLLKDVPFNTLPMYKFRELFQSRFKTSISVLDLYKMQDICTINSDNNEEKFISLNPELVNTLDISP--------------LMEGLQHSVPYCSIHFK-KEQHKGWAEQEIEPLPNVFMSISEIQKLIYPLLKVHTGDIPVATLLHCVKEELNVSIMANEN--GVNLEHLICCVQGIQVRANNFGIKILGWLEINKEMQSGTFNASSNTCSLTASDRTNCGSYFKNSVADPLFQISREVIELLKMSPKSTMKFNRFIPAYHNHFGKQCRVADYGYTKLIELFEALSNVVQIMGDGENRQITLSHRIQIRRFTSDLLRVLRANGNNSVLLSQLPLVFTQTQNKTFDITDYGVCDLIDILDGLVSSNIVTLGAAQNGKDILISMPKRKQTNSELEKTCVFAGEMVELFQNALQYTILFQKFVRSYHYHFAYQCRLSDYGFLKLADLLDAINGLVEMKLTSDEDKKIVLSPQVARRVFAEQCENLIRNATGNSSHCMKLEQVLVLHKKKYGYQIQPKTLGVMDMATAVELLPYVELKKKEQAIWLICHNNDHEFRFLCYRVCKYVMERDPSASVWTNVRGEVKLTKSQQFVKPIEKSILVRDFNAKYKDHLSESALLAMRQAIEVYD-DGGIQCIRLTRFMKFIIAIVRMLEQRPSMYLYEIKNGLNCGLSTTFEFGFPNLYSVVAAHKDLFSINNGPTQERSEVSINMNCELRQSSLSKDQCVLESQKLTNSKHRAQRSFHSHIGEHNGLPISQPPLKRSATINNCSTFQTYHADTDIFNVPANCLPPRTNLSLPNSFGSSLESGSFSNSYSNKENSMKSLHLFNSSFNSSGELNASLGAGDLTNISLGTGIAVDTSNEPSELWRRRQQNFNRPNSSNFRKSDNGTDGTYTIGNYIAPPIGSIYEPLKYNGQDKEKLPFWIDPIWSKGSEQLRHDILNIRLPKARTTKTFSNILSPYTISKNENLKRQLFSFDNHDRKIA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :*: : * ..* : **.. : :.: :*: .*. :: ..: : :. :*. . : *:: . :. *. *:.: . * : :..**. :* . : * . ..:. ..*:.. * ..:. : . :.:*. : * *: : *: **: *:*. : : *::. :. * .* * :.: * : . . . .:::. :.: : : .:. : : :::.. :*::*:** *....::.:* : : * *: :. : * * : :* * .*..*** *** *::*** : .:: ..:. * :. .:*:*.* **::** ::::.:: .:.* ****: * :*..:.* . . * .. .. :.. ::* *:: . * * . *: : : : :* *.:*:. : ::.**:.* * :*: :: .* *:. :.:: ** ***:* *: *::: : : *:*:: *:. : . ::. * :.. . *:*:*****:*** .*.. : ...*** **:**.*****:****:*****:**:.:*:**:* *.:* :**:** *::***.***::*:::..:.*:: ::. .: .* :*:*:****:****:. : .: *: :*:..:::*.: **::*:.*:*:* *: ::*:*::: :: : *:**: ***:**. **:*: *** ** :*::** ::: .:* * :.*: :.:* * :*:*. ..* *: : :::. : *.:** :: : .* .::: .: * :* . :: * . :.:* * :: :*. : : : .: . :. . ::* * .::. . * :: :** * : ::** : * : :*. *:.: *:.. *:.. .. . *. . :: : * *.: . *.*. : *: :*:. * . *: ** ... :* * *. : : .. : : : . . . * . ** ::. ..: : .:::: : * . : . .:. : . .** * . .:* :. * : .*. :: : :::: :* ", "identical_positions": 252, "similar_positions": 471, "identity": "13.53%" }, { "cls_id": "homologset.agr.MGI:2444506", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43462-1", "uniprot_id": "MBTP2_HUMAN", "id": "O43462-1", "name": "Membrane-bound transcription factor site-2 protease", "aln": "MIPVSLVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLPARKAVEATQVCRTNKDCKKSSSSSFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVVVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CHX6-1", "uniprot_id": "MBTP2_MOUSE", "id": "Q8CHX6-1", "name": "Membrane-bound transcription factor site-2 protease", "aln": "MIPVSLLVVVVGGWTAVYLADLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTSIFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSPYSSSSSSSSSSSSSSSS----SSSLHNEQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLPARKAVEATQVCRSNKDCKSGASSSFCIVPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVIVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:********.***:**********************************::*******************************************************.***************** ****************************:******************************************************************************************************************************************************************************************************************:*****..:******:***************************************************:*******************************************************************************", "identical_positions": 502, "similar_positions": 13, "identity": "96.72%" }, { "cls_id": "homologset.agr.MGI:2444507", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LIQ2-1", "uniprot_id": "A0ABK0LIQ2_RAT", "id": "A0ABK0LIQ2-1", "name": "", "aln": "MAATKTWVLSFLVLEVTTVLGRQMMLTQSARRVQPVKRTPKILTKPVNSQESPGEWTTWFNIDHPGGQGDYERLDAIRFYYGERVCARPLRLEARTTDWMPAGITGQVVHGSPREGFWCLNKEQRPGQNCSNYTVRFLCPPGSLRRDTEHIWSSWSPWSACSAACGHTGVQTRTRTCLAQTVSLCNEATEEGQLCMSQACTACDLTCPMGQVNADCDACMCQDFMLHGAISLPGGGPAPGATVYLLAKAPKMLTQTDSSGSFRVPGLCPDGKTVLKVTKSKFAPIMITMPKTSLKSATINAEFVRAETPYIVMNPETKARRAGQSVSLCCKATGKPSPDKYFWYHNNTLLDPSLYKHQSKLVLRNLQQDQAGEYFCKAQSDAGAVKSKVTQLTVIAHDEAPCNPTPESYLIRLPHDCFQNATNSFYYDVGRCPIKTCAGQQDNGIRCQDAVENCCGISRTEEREIQCSGYTLPTKVAMECSCQRCAETRSIVRGRVTAADDGEPMRFGHVYMGNNRVSMTGYKGTFTLHVPQDTERLVLTFVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRQKEPITLEATETNIIPLGEVAGEDPVAELEIPPKSFYKQNGEPFTGKVKASVTFLDPRNVSTATATQSDLNFINDEGDTFPLRTYGMFSVDFRDEATSESLNAGKVKVHLDSTQVKMPEHARAMKLWSLNPNTGLWEEEGDFKFESQRRNKREERTFLVGNMEIRERRLFNLDVPESRRCFIKVRTYRSERFLPSEQIQGVVVSVINLEPRTGFSSNPRAWGRFDSVITGPNGACLPAFCDDQSPDAYSVYVLASLSGEELEAVESSPKFNPNAIGVPQPYLNKLKYRRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLRACEEAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIVGPLEVNVRSRNMGGTHRQTVGKLYGIRDVKSTRDRDQPNVSSACLEFKCSGMLYDQDRVDRTLVKVIPQGSCHRASVNSMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVTDQDPGTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCAERQVGRQSAFQYLQSTPARSPATGTVQGRVPAMRQQRASRGGLRRRGSMAPLRFSGVAQQPLSN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66K08-1", "uniprot_id": "CILP1_MOUSE", "id": "Q66K08-1", "name": "Cartilage intermediate layer protein 1", "aln": "MAAIKTWVFSFLVLEVTTVLGRQTMLAQSVRRVQPVKRTPKTLAKPADSQESPGEWTTWFNIDHPGGQGDYERLDAIRFYYGERVCARPLRLEARTTDWMPAGSTGQVVHGSPREGFWCLNREQRPGQNCSNYTVRFLCPPGSLRGDAEHIWSSWSPWSKCSAACGHTGVQTRTRTCLAQTVSLCSEATEEGQLCMSQACTACDLTCPMGQVNADCDACMCQDFMLHGAISLPGGGPAPGAAVYLLAKAPKMLTRTDSSGRFRVPGLCPDGKTILKITKTKFAPIMITMPKTSLKSATINAEFVRAETPYIVMNPEMKARRAGQSVSLCCKATGKPSPDKYFWYHNNTLLDPSLYKHESKLVLRNLQQDQAGEYFCKAQSDAGAVKSKVTQLTVIAHDETPCNPTPESYLIRLPHDCFQNASNSFYYDVGRCPIKTCAGQQDNGIRCRDAVENCCGISRTEEREIQCSGYTLPTKVAVECSCQRCAETRSIVRGRVTATDNGEPMRFGHVYMGNNRVSMTGYKGTFTLHIPQDTERLVLTFVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRQKEPITLEAMETNIIPLGEVIGEDPVAELEIPSKSFYRQNGEPFTGKVKASVTFLDPRNISTATAAQSDLNFINDEGDTFPLRTYGMFSVDFRDEATSESLNAGKVKVHLDSTQVKMPEHVPAMKLWSLNPDTGLWEEEGDFKFESQRRNKREERTFLVGNMEIRERRLFNLDVPESRRCFIKVRTYRSERFLPSEQIQGVVVSVINLEPRTGFSSNPRAWGRFDSVITGPNGACLPAFCDDQSPDAYSVYVLASLSGEELEAVESSPKFNPNAIGVPQPYLNKLKYRRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLRACEEAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIVGPLEVNVRSRNMGGTHRQTVGKLYGIRDVKSTRDRDQPNVSSACLEFKCSGMLYDQDRVDRTLVKVIPQGSCHRASVNSMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVTDQDPRTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCAERQVGRQSAFQYLQSTPARSPATGTVQGRVPAMRQQRASRGGLRRRGSMAPLRFSGVAQQPLSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75339-1", "uniprot_id": "CILP1_HUMAN", "id": "O75339-1", "name": "Cartilage intermediate layer protein 1", "aln": "MVGTKAWVFSFLVLEVTSVLGRQTMLTQSVRRVQPGKKNPSIFAKPADTLESPGEWTTWFNIDYPGGKGDYERLDAIRFYYGDRVCARPLRLEARTTDWTPAGSTGQVVHGSPREGFWCLNREQRPGQNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQDCTACDLTCPMGQVNADCDACMCQDFMLHGAVSLPGGAPASGAAIYLLTKTPKLLTQTDSDGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESYLIRLPHDCFQNATNSFYYDVGRCPVKTCAGQQDNGIRCRDAVQNCCGISKTEEREIQCSGYTLPTKVAKECSCQRCTETRSIVRGRVSAADNGEPMRFGHVYMGNSRVSMTGYKGTFTLHVPQDTERLVLTFVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRRKKPITLEAMETNIIPLGEVVGEDPMAELEIPSRSFYRQNGEPYIGKVKASVTFLDPRNISTATAAQTDLNFINDEGDTFPLRTYGMFSVDFRDEVTSEPLNAGKVKVHLDSTQVKMPEHISTVKLWSLNPDTGLWEEEGDFKFENQRRNKREDRTFLVGNLEIRERRLFNLDVPESRRCFVKVRAYRSERFLPSEQIQGVVISVINLEPRTGFLSNPRAWGRFDSVITGPNGACVPAFCDDQSPDAYSAYVLASLAGEELQAVESSPKFNPNAIGVPQPYLNKLNYRRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLRACEEAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIVGPLEVNVRSRNMGGTHRQTVGKLYGIRDVRSTRDRDQPNVSAACLEFKCSGMLYDQDRVDRTLVKVIPQGSCRRASVNPMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVTDQDPRTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCVERQVGRQSAFQYLQSTPAQSPAAGTVQGRVPSRRQQRASRGGQRQGGVVASLRFPRVAQQPLIN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NUZ8-1", "uniprot_id": "A0A8M1NUZ8_DANRE", "id": "A0A8M1NUZ8-1", "name": "", "aln": "MGCLSTWTFLLLLLGITGTISQGTWRGIMGTSWRP---NPAVYHN-----EDNYEWTTWFNVDHPGGKGDYEKLNVIRYYYRARVCEVPRALEARTTDWIPARSTGERVHADPAVGFWCVNDEQPFGKNCSNYAVRFLCPRDIVSDVEEGIWGQWSDWSLCPAQCDEEATQHRSRSCQSNSK-QCSGKSVEARSCHGPPCPRCDLQCIVGTVNSECDGCMCQDHTVLGSVRSAGGLPAPGAAILRAGSSPKLLTVTDHNGHFQVPGICPDGNTTLMVKLSNHAPHQVTVPPSKERTTVLLLRLERAKKLHVLKNPEDRARREGQTAAFCCKIDGTPGPSSYEWFHNGTLLDRSQYQYDETLVLRNLSLDHVGEYYCRGSNENGAIKSKPATLTVIGQKEPSCNPRPDSHLIRLPHDCFQNETNSLYFDVGRCPTTKCTGKLDNGIRCKDSVSYCCGVSNMEEREITCQGYQLPIMVVTQCGCKTCVDTKAIVRGRAVAADTGEPMRFGHIYMDGVKLSRTGYKGTFSIQVPTNTERLVLTFVDNMQKFVNTTKVLPFNPRGGAVFHEVKLLRKKPAVIISSRETNTLDLGEVEGQDPVAEIEIPPNAFYKENGEVFMGNVKASVTFLDPRDVSTAAAAQSDLNFIGDEGDTLPLRTYGMFSVDFRDEEGGESLNAGEVKVRLDAAQVKMPEHLKTMKLWSLNPETGLWEEEGHFYAEKKQRGKREERTFLIGNMEIRERRLFNLDVPENRRCYVKVRAFRSERYMPSEQTEGVVMTLINMEPTPGFSTNPRAWGRFDSVITGPNGACLPAFCDEQKPDAYSAYVMANLGGEELEAVASSPKLNPNTIGVPQPYLNKLNYRRTDHDDPRIKKTAFSINVAKPRSNVAEEANGPVYAFDKLKECEEASFSAAHFRFSRVEGDRYDYNTVPFNEDDPMSWTEDYLSWWPKPMEYRACYIKVKLNSPHELNVRSRNMGGTHPRTVGQLYGIRDTRSIRDMDQATVSAVCLEFKCSGMLYDQDRVDRTLVKVMPQGSCKRDSVNSMLQEYLVNHLPLAVNNDTNEFTMLAPLDPLGHNYGIYTVTDQDPRTAKEIALGRCFDGTSDGTSRVMKSNEGVALTFTCGDKEVTRQSMFQQIQNSLGQATAGSARPGRG--NRRQRGSSTAPRS-SQRRSTRNSITRSQSLG-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .:*.: :*:* :* .:.: :* .* : *. *******:*:***:****:*:.**:** *** * ******** ** **: **..* ****:* ** *:*****:****** . : * **. ** ** *.* *.. ..* *:* * :: *. : *.: * . *. *** * :* **::**.*****. : *:: .** **.**:: .:**:** ** .* *::**:****:: * :. :.** :*:* :. :::.: .: **:. ::: *** :*** **:.::*** *.* *..* *:**.**** * *:::..****:*. .:.***:*:...: **:*** : * **. .*..*** *:*:*********** :**:*:****** ..*:*: ******:*:*. ***:*. ***** *.** ** *. :*.*: *.:*::*****. *:* ********:**.. ::* *******::::* :**********.:************* :*.*****:*:**:* .: :.: *** : **** *:**:**:***..:**::*** : *:***********::***:*:*:*****.*****:*************** .*.****:***:**::******* ::*******:********.* *.::*.***:****:**:**************.***::***::****::**** :***:::**:** .** :*******************:*****:*.*****.**:*.*.****:** ****:***:***********:******:***:*****.*.:****.* ***:***:***::*: ****. ******* ::*************************:*******:********: .* *:*********** :***:******.:* ** **..**:.***********************:*****:* ***.**:***************.*:*********************** *****************:**:**** ******.* :::* *** ** :*.: .::.* .: ** *:**.* . * . . * . . .*.* ", "identical_positions": 713, "similar_positions": 282, "identity": "60.22%" }, { "cls_id": "homologset.agr.MGI:2444508", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWT2-1", "uniprot_id": "D3ZWT2_RAT", "id": "D3ZWT2-1", "name": "", "aln": "-------------------------------------------MEHLERCAWFLRGTLVR--AAVRRHLPW-------VLVAAMLVGSALKELS-PLPESYLSNKRNVLNVYFVKLA-----------------WAWTVCLLLPFIALTNYHLTG---KTSLVLRRLSTLLVGTAIWYMCTALFSNIEHYTG------SCYQSPALEGIRQEHRTKQQ-CHREGGFWYG-FDISGHSFLLTFCALMIVEEMAVLHEVKTDRSHHLHV-----------------------------------AITTLVVALGFLTFIWVW------MFLCTAVYFHDLIQKVFGTMFGLLGWYGTYGYWYLKSFSPGLPPQSSSLTLKQDTYKK---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59266-1", "uniprot_id": "FITM2_MOUSE", "id": "P59266-1", "name": "Acyl-coenzyme A diphosphatase FITM2", "aln": "-------------------------------------------MEHLERCAWFLRGTLVR--ATVRRHLPW-------ALVAAMLAGSVVKELS-PLPESYLSNKRNVLNVYFVKLA-----------------WAWTVCLLLPFIALTNYHLTG---KTSLVLRRLSTLLVGTAIWYICTALFSNIEHYTG------SCYQSPALEGIRQEHRSKQQ-CHREGGFWHG-FDISGHSFLLTFCALMIVEEMAVLHEVKTDRGHHLHA-----------------------------------AITTLVVALGFLTFIWVW------MFLCTAVYFHDLTQKVFGTMFGLLGWYGTYGYWYLKSFSPGLPPQSCSLTLKRDTYKK---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N6M3-1", "uniprot_id": "FITM2_HUMAN", "id": "Q8N6M3-1", "name": "Acyl-coenzyme A diphosphatase FITM2", "aln": "-------------------------------------------MEHLERCEWLLRGTLVR--AAVRRYLPW-------ALVASMLAGSLLKELS-PLPESYLSNKRNVLNVYFVKVA-----------------WAWTFCLLLPFIALTNYHLTG---KAGLVLRRLSTLLVGTAIWYICTSIFSNIEHYTG------SCYQSPALEGVRKEHQSKQQ-CHQEGGFWHG-FDISGHSFLLTFCALMIVEEMSVLHEVKTDRSHCLHT-----------------------------------AITTLVVALGILTFIWVL------MFLCTAVYFHNLSQKVFGTLFGLLSWYGTYGFWYPKAFSPGLPPQSCSLNLKQDSYKK---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q52KL1-1", "uniprot_id": "FITM2_DANRE", "id": "Q52KL1-1", "name": "Acyl-coenzyme A diphosphatase FITM2", "aln": "-------------------------------------------MAAAVAGSLVDKLVCLWRQPYTRIYLPH-------LFFCISLVGSVLKNAE-LVPESYFSSSRNVLNLYFVKVS-----------------WGWTIVLLLPFIAYSNFYIK----SHMFALRRLTSLLVATLVWYICTETFFYIEDITG------SCYESNTMVVIRGEFDTKAA-CRKAGFFWDG-FDISGHSFILSYSSLVIMEEMVPMLHIQP---AYRNP-----------------------------------PLDCLYLALNVIVAIWIW------MFGCTSVYFHDIIDKILGTSCGILGWYMTYKVWYVKLFSPGLPPQP-----KQHT------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRJ2-1", "uniprot_id": "FITM2_DROME", "id": "Q9VRJ2-1", "name": "Acyl-coenzyme A diphosphatase FITM2", "aln": "-MATKRRPLRPNLGGTAGSPSSSGSNMNFRPGGPDITRSEARGTRPTAAPTSIREILVMGVIHLCKKTIFFNTDLKVALYLGSLFVISVIGDFV-PFPKTYFARSDNLFNQYFVKIG-----------------WGWTLLFVVPFLVLSAYTITCG-DHKRMLRHHFPRIVIATFFWFFWTKLFNVVENSYG------RCTT--------KGYATKSS-CLKAGHLWKG-FDISGHAFILIHSSLVLIEEARPIIRWETIKEHIRNERHNRSTAENSGTNPLRTLNEEQMRSLQFLYKRLTPIIRTLFIGMAALQLLWDI------MLVGTMLYYHRMIEKVISGIIAILTWYFTYRFWYPTPGLLPEAPGNGSFSYQREIPTFPFKRPSHLSTGAATTSSGSNSSRTNLNGKAATTGVPRDQQIPTFMGMPLFTSPKAASAAANLLMSDQQKRERDREQQTLES", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53012-1", "uniprot_id": "SCS3_YEAST", "id": "P53012-1", "name": "Acyl-coenzyme A diphosphatase SCS3", "aln": "MSSKWFNAIHLLVCPLTVLVGYLMNAYGYGAALQATLNKDGLVNAMLVKKGWFWTSLVGWWCIIRYRAVPGATGRDRRHIVQSFKRYAILTVWWYVFTQGIWFGVGPIMDLVFVYTGGHCHYDVFDDAGHVNEDFQGSVTRTNRALALIHNVLTLHGHHQEHRQQQLWDRSIGSIQGALQATQPKTPKNVTASAAAAINTFIHDQMHRWQGPLTTSAQ-CRRFGGHWAGGHDPSGHVFLATLMCMFLLGELRVFGRRALAHLYAQKW-----------------------------------QLVRLVTRLFDTGPLWTWRRCGGGSMTCGARLWRAIVEPPVTCAAALLRLTRCIACDHPVIILLTLLVTWLWQLLLTAVASRFHTVREHMSGLLAAYIVTGLVYARDAAALRPV-------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06676-1", "uniprot_id": "YFT2_YEAST", "id": "Q06676-1", "name": "Acyl-coenzyme A diphosphatase YFT2", "aln": "----------------------------MIRQLNYWSRKAYLIYPFQVFVGALLSIVVSSETLNHQKETCA--------LLKSSNIFNVIFAYKANQLWPFLFFSLAFLQIYFHYLAR-----------------MDILPLPISSTETSSSYLTYTN-HWPLLKNRIISIMITQYACKFVLKYLLLFLNFQFID----HVFIWTGGECSSGSKTTSAEKCRLENGKWDGGFDISGHFCFLVSISMILWMELHLFSRFVQAEDMFWVVN---------------------------------KWVRACLAIVCAVLVIWIC------ILWVTAIYYHTILEKVLGCLMGFICPVFIYHILPKIGILHNYLYL----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : .:: * . . :. .:: : : . :. * . * * .* *** : .:.: * : . : : :* : :: : : . .:: ", "identical_positions": 10, "similar_positions": 39, "identity": "2.15%" }, { "cls_id": "homologset.agr.MGI:2444509", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZW03-1", "uniprot_id": "A0A8I5ZW03_RAT", "id": "A0A8I5ZW03-1", "name": "", "aln": "--------------------------------MEASADSSEASAACRFFLEGRCRFGARCRQPHPGAPAPSPEVAQP------------------------------EARSKKPALRTAADVIRRIRWDPRLDPADFSVGYTDRFLGVQEEPFCAFCWDEPLAALG-PGVLAVPQHRIRYFRFRGRLVWDRASRTDLIFGSGSVAGRGPTILDALDDRDEHWREVKAEIPDTEKTGVGFEDLDTQGAPEEGGGNPTTTGLDTGLETQEEGGAIKETRTGLDSGLETPEEGGTIKEARTELDSSLETPEVDGPTKETVLNGTTELETPDPSI-CCSGVKEISVQ---VPKATVLSQWQVQVLETSGLSADEMESVWDPGAWPDDRR------APRKPRPTHFVALMVTEPGLRAEVVKAQEHLVRIAPYCAEFLVPAQALHLTVVLLRITGPGEEAAAVRALRRAILKPGLQAPSELQFR-DLILLGHHVLCATPSP--TLASMVQTLNQRLEAEGLRVVQLP-ELQPHLTLAKVPHG-----TQVCLPKPEYILNEELGRQPLEKLWLCRMGR---AGQSYLPLAQIPLN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTN6-1", "uniprot_id": "LENG9_MOUSE", "id": "Q8BTN6-1", "name": "Leukocyte receptor cluster member 9", "aln": "--------------------------------MEASADSSEAPAVCRFFLEGRCRFGARCRQPHPGAPAPSPVVTQP------------------------------EAGSKKPALRTAADVIRRIRWDPRLDPADFSVGYTDRFLGVQEEPFCAFCWDEPLAALG-PGVLAVPQHRIRYFRFRGRLVWDRASRTDLIFGSGSVAGRGPTILDALDGGDEHWTEVTAEIPDTEKTGVGLEGLDTQDALAEAGGNPTGTGLDSGLETHEEGGAIKETRTGLDS--------------------SLETPEVDGPTKETGLNGTTELEMPDPSM-NFSGVKISSVE---EPRATLLPQWQAQGMETKGLSAEEMGNVWDPGVWPDDRR------APRQPRPTHFVALMVTESGLRAEVVKAQEHLVRIAPSCAEFLVPAQALHLTVVLLRLTGPGEEAAAARALRRAILKPGLQAPSQLQFR-DLVLLGHHVLCATPSP--TLTGMAQTLNQRLEAEGLRVVLLP-ELQPHLTLAKVPHG-----TQVCLPKPEYTLNQELGRQPLSKLWLCRMGR---AGHSYLPLVEISLK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96B70-1", "uniprot_id": "LENG9_HUMAN", "id": "Q96B70-1", "name": "Leukocyte receptor cluster member 9", "aln": "MGSRPPCGATSSARRACQFPAPMAAAREPELPQEAPATEPAPPPACRFFLEGRCRFGARCRQPHPGAPAPPGREAQP------------------------------EAGAKKPPLRTAADVIQRIRWDPRLDPADFSVGYVDRFLGVREEPFSAFCWDQPLAALG-PGVLAVPQHRVRFFRFHGRLVWDRASRTDLVFGSGSAAGRGPTILDAPNTEGAHG----AEGAEWTLAGTG---QEAQAAPKRGSTRPLCTG-------HQEPG--------------------------------VEEPGELEAAQERALGTAADLGTLAPRG-RLAGVTEEALKPTAATRTTLLGGKEAQALGVPGGSAETTEAEWGPAAWPEDKRARLSVAAPCQPRPTHFVALMVTEPGLQAEVTKAQEYLVHVAPHCANFLVPSQNLHLTLALLRLAGAGEEAAAIGALRRALLAPGLNAPPRLSFR-KLVLLGPHVLCAPPSP--TLESMAQVLSQRLEAEGLSTLQSPGQLHPHLTVAKVPHG-----SQVHLPKLEFTLSQEVGCQPLQTLWLCRIGR---TGGPFQPLAEIRLE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6J5-1", "uniprot_id": "A0ACD6B6J5_DANRE", "id": "A0ACD6B6J5-1", "name": "", "aln": "------------MEIEEETTRGNPTEESDQQIQPDEIKQETGPNICQHFLLGRCHFGDRCRLSHSVLDVPQTTNSEKDDTAVTEKQSKSRKNGKKCHTDIQHENIEKKGSKKKPRMRTADEVISRIIWDASVHPDDFIVGHLDRFLGVLERPFSDFSWDTQVCDCDFSEELALPRHRIQYFSYKGQRVWDRDSRTDRVFGS-----TGQTILPPFCGENQQQDNLTSDTGQQEESTNAADVSTDPDQSTELSEVQDDVASVITPSKNKQSQGDALNHSGNEN------------------AEEETKDHILLSRTESAPEGENTATAEDPTLNHLAGNLTVTQK---VEQAEIAEEWKDSWDGVSGSEAELASAILPQ---PQSKR-------PPPRKPTHFICFRVDSPAALQAFQRVQRKVLSTLPQSEPMWVNPATLHVTLSLLVLN-SAEEVSAAAELMRTIVRSSHKPPISVTFAPKLKHFNGTVLHVVPQPSSDVQSLNSPLQEAFKDKGWLHRHSR-CPSYHLTLAKVKREPKAEKMFEGIGTVKLAKDVNFGKLEVNKLYLCVKGQRNTESGFYQVVCAVQLPNV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *:.** ***:** *** .*. .* :: :. *** :*** :** ** **. :.* ** **: ****** *.**. *.** :. . . **:*:**:::* ::*: **** **** :*** * *** . . : :: : : . . . .. ::: . * * :* : : :: : : . . * .*: *:.:* * :****:.: * ... . :.*. :: * . : * . **:*: ** : ..**.:* * *::: .. :.* : * .* :. ** . *.* : .: . *.: :: :* ***:*** : : . : . :.* :..*:** *: . : : : * ", "identical_positions": 111, "similar_positions": 126, "identity": "18.75%" }, { "cls_id": "homologset.agr.MGI:2444516", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BXL9-1", "uniprot_id": "IFFO1_MOUSE", "id": "Q8BXL9-1", "name": "Non-homologous end joining factor IFFO1", "aln": "------------------------------------------------------------------------------------------------------------------------------------MNPLFGPNLFLLQQEQQGLAGPLGDPLGGDHFAGGGDLASAPLASAGPSAYSP--PGPGPAPPAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQG--RRGLARRDQAVQTGFIS--PIRPLGLPLS------SRPAAVCPP----------------------------SARVLGSPSRSPAGPLASSAACHTSS--STSTSTAFSSS--TRFMPGTIWSFSHARRLGPGLEPTLVQGPGLS--WVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQERVTELQEEAQEADACQEELAMKVEQLKAELVVFKGLMSNNLTELDTKIQEKAMKVDMDICRRIDITAKLCDLAQQRNCEDMIQMFQKKLVPSMGGRKRERKAA--------VEEDTSLSESDGPRQPEGAEEESTALSINEEMQRMLSQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQ-EDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPPPPPSETEDSDRDVSSDSSMR-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ACM7-1", "uniprot_id": "A0A8I6ACM7_RAT", "id": "A0A8I6ACM7-1", "name": "", "aln": "MNFSFHFLVSKEKAIELDPRYRGEEAVGKAASKVPEVLCLRSYSQDLRRWFPRKGESGSSNVDSTHRTSDPGKVQSKSSNEGFSLASSAPSFMTFGLLPGHLIGHSYSTNISLARLLTLCCTGLPLPAEGAAMNPLFGPNLFLLQQEQQGLAGPLGDPLGGDHFAGGGDLPSASLASAGPSAYSP--PGPGSAPPAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQG--RRGLARRDQAVQTGFIS--PIRPLGLPLS------SRPAAVCPP----------------------------SARVLGSPARSPAGPLASSAACHSSSSTSTSTSTAFSSS--TRFMPGTIWSFSHARRIGPGLEPTLVQGPGLS--WVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQERVTELQEEAQEADACQEELAMKVEQLKAELVVFKGLMSNNLTELDTKIQEKAMKVDMDICRRIDITAKLCDLAQQRNCEDVIQMFQ---VPSMGGRKRERKAA--------VEEDTSLSESDGPRQPEGDEEESTALSINEEMQRMLSQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPPPPPSETEDSDRDVSSDSSMR-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0D2I5-1", "uniprot_id": "IFFO1_HUMAN", "id": "Q0D2I5-1", "name": "Non-homologous end joining factor IFFO1", "aln": "------------------------------------------------------------------------------------------------------------------------------------MNPLFGPNLFLLQQEQQGLAGPLGDSLGGDHFAGGGDLPPAPLSPAGPAAYSP--PGPGPAPPAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQG--RRGLGRRDQAVQTGFVS--PIRPLGLQLG------ARPAAVCSP----------------------------SARVLGSPARSPAGPLAPSAASLSSS--STSTSTTYSSS--ARFMPGTIWSFSHARRLGPGLEPTLVQGPGLS--WVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQ---VPSMGGRKRERKAA--------VEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQ-EDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPPPPPSEAEDSDRDVSSDSSMR-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QFE6-1", "uniprot_id": "F1QFE6_DANRE", "id": "F1QFE6-1", "name": "", "aln": "----------------------------------------------------------------------------------------MPDFEHFRFSYSRMNPVLGENVYSFQQNQ------LTGFADSASSGHWTDPAGLYLSEHTGG--------IGQD----GLDMGALPPPGSPYLHLGNYLHRVSPPPPAATALRNDLGSNISVLKTLNLRFRCFLAKVHELERRNKVLEKQLQQALDENAECAETKKPLTRDVGVQTGFVGLIPIRPDLIPIQNANDTAYLSGSLLSP--TPIIPLEPTNRTAVENFLNPSKLTDSNSNLTPNFPISPIDPAPKPLSNING-KYVSTV-IGCTSNPPPRFHPGSAWSYN--QRFGTGRE-SRISGPGVSSSWVPPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTMRVDLQEKVAELEEDLQESEVCQDELALRVKQLKADLVLFKGLMSNNHSDLDSKIQEKAMKVDMDICRRIDITARLCDVAQQRNCEDMIQIFQQVATPPSTLTRRPRKPAPQTIRGNDSDEPISISESEESGNKEVELCCSSNNQINEEMQRMLNQLRESEFEDDCDSLAWEETEETLLLWEDFPGYTFSVEN-QGEQ-EESIEKVIKDTESLFKSREKEYQDTIDQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPLLAPAAVEEGENAEKERKRATAANSDSAEPYYDMQANSSVPDHTWKKA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B5R2-1", "uniprot_id": "A0ACD6B5R2_DANRE", "id": "A0ACD6B5R2-1", "name": "", "aln": "----------------------------------------------------------------------------------------MPDLQRFSFPYRSMNSPLHHHHHHHQQQQ------HQQHQHPEEPGHPDSPSSLLPEAAIFGAPDPSSFFLGEQPVPAGVTQSALDLTASSYLHFSPSLHWSQPPPPTAMALRNDLGSNISVLKTLNLRFRCFLAKVHELERRNKILELQLQQALDSNNKGGCTEDGKTKEIGVQTGFIGPIAVRPGSLSFQNTNNSAKRPTTLFMPSLTTVLKLEP-NKPGDETTSDPN--INRNPTITVSLSTPTTEPASANTNNSNNTPHVSSVGTGTSPNPPPRFLPGTIWSYNHTRKLGSGTE-TRVTSPGVS--WVHPDGVGVQIDTITPEIRALYNVLAKIKRERDEYKRRWEEEYTMRMDMEQRMNELQEDLQESEVCQDELALKVQQLKAELVLFKGLMSNNLSELDSKIQEKAMKVDMDICRRIDITARLCDVAQQRNCEDPIKIFK-VPSPQNAITSRARKQASQPANGSETDEPVSTSESDGGGAREDEVCTPSTLQINEEMQRMLTQLRECEFEDDCDSLAWEETEETLLLWEDFPGCTVSTDTSQGEQ-EECLEKVIKDTECLFKSREKEYQETIDQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGNNKSTSPIPGGGID-TNGETERDKMEEGGR-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* : . * :* : * . . : . ..**:* **********.***********************::** ******:.. : . :: .*****:. .:** : : . :: * .. : . . .. * . .. ::. :.. .** **: **:. :::*.* * : : .**:* ** ************************:****************:*::::::: **:*: **::.**:***::*:****:**:******** ::**:*********************:***:******** *::*: * * ** * :* * ***: : .: .*********.**** :********:**************.* :.:. **** *:.:********.***:******:*************.**********************************:.**. . : .* . ", "identical_positions": 291, "similar_positions": 117, "identity": "37.99%" }, { "cls_id": "homologset.agr.MGI:2444518", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N8I0-1", "uniprot_id": "SAM12_HUMAN", "id": "Q8N8I0-1", "name": "Sterile alpha motif domain-containing protein 12", "aln": "MAVEALHCGLNPRGIDHPAHAEGIKLQIEGEGVESQSIKNKNFQKVPDQKGTPKRLQAEAETAKSATVKLSKPVALWTQQDVCKWLKKHCPNQYQIYSESFKQHDITGRALLRLTDKKLERMGIAQENLRQHILQQVLQLKVREEVRNLQLLTQGTLLLPDGWMDGEIRRKTTLL--------------------------------LGQTGVRENLLLFLHR--ISIIENSIQI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0VE29-1", "uniprot_id": "SAM12_MOUSE", "id": "Q0VE29-1", "name": "Sterile alpha motif domain-containing protein 12", "aln": "MAVEALHCGLNPRGIDHSAHADGIKLQIEGEGVESQSIKNRTFQKVPDQKGTPKRLQGEAETAKSATVKLSKPVALWTQQDVCKWLKKHCPNQYQLYSESFKQHDITGRALLRLTDKKLERMGIAQENQRQHILQQVLQLKVREEVRNLQLLTQASVECSP-----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LW70-1", "uniprot_id": "A0ABK0LW70_RAT", "id": "A0ABK0LW70-1", "name": "", "aln": "MAVEALHCGLNPQSIDHPAHADGIKLQIEGEGVESQSIKNRNFQKVSDQKGTPKRLQGEAETAKSATVKLSKPVALWTQQDVCKWLKKHCPNQYHIYSESFKQHDITDIHQGSEKAKSHTRRKYFLKSTYNSIHETAQMGRPFEERKWTRASPAETHRQEAGAHGGRPGEPATAHPAAGAPTEGSGRSQKPAVTHTRYPAASWWVGAPGEHGKTEHVIIATEESQKKFVVVSLQNFLH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8ML92-1", "uniprot_id": "AVE_DROME", "id": "Q8ML92-1", "name": "Protein aveugle", "aln": "---------------------------MGEETINSTQNKTR------------------------TKTTRPKAVYLWTVSDVLKWYRRHCG-EYTQYEQLFAQHDITGRALLRITDSSLQRMGVTDNRDREAIWREIVKQRLKTDIMEIRDMERLNIY--------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ::* . *.: :... .*.* *** .** ** ::** :* *.: * *****. . .. * : : * . : : : . ", "identical_positions": 24, "similar_positions": 29, "identity": "10.08%" }, { "cls_id": "homologset.agr.MGI:2444520", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CCH2-1", "uniprot_id": "NHLC3_MOUSE", "id": "Q8CCH2-1", "name": "NHL repeat-containing protein 3", "aln": "--------------------------------------------------MARAWVCLAGAAFFLSCLVLHSRFCGSLVSRTFSFHVSWRMEDPLFRLDLGWPKNSEYFTGATFCVAVDSLNGLVYVAQRGDNIPKVLVFSEDGYFLRAWNYTVDTPHGMFVSGTPFEQSVWITDVGSGPYGHTVKKYNSLGDLVQVLGTPGKKGTGLNPLQFDNPAELYVDDTGEMYIVDGDGGLNNRLVKLSQDFMILWLRGENGTGPAKFNIPHSVTLDAVGRVWVADRGNKRLQVFDKDTGEWLGAWDNCFTEEGPSAVRFTPDGKYLIVAQLNLSRLSVLLAPPSGSIGDCSVVSTIQLADQVLPHLLEVDRKTGAVYVAEIGAKQIQKYIPWHSRTPAFGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2F6-1", "uniprot_id": "D4A2F6_RAT", "id": "D4A2F6-1", "name": "NHL repeat-containing protein 3", "aln": "MYFSERGSHCFSVTVPSLFSFAVLCFDSWMLPLPQTRLQAPLTFTSQALRMARTWVCLAGAVFFLSCLVLHSRFCGSLVSRTFSFHISWRMEDPLFRLDLGWPKNSEYFTGATFCVAVDSLNGLVYVAQRGDDIPKVLVFSEDGYFLRAWNYTVDTPHGMFVSGTPYEQSVWITDVGSGPYGHTVKKYNSLGDLVQVLGTPGKKGTGLNPLQFDNPAELYVDDTGEIYIVDGDGGLNNRLVKLSQDFMILWLRGENGTGPAKFNIPHSVTLDSVGRVWVADRGNKRLQVFDKDTGEWLGAWDNCFTEEGPSAVRFTPDGRYLIVAQLNLSRLSLLAAPPSGSIGDCTVVSTIQLADEVLPHLLEVDRKTGAVYVAEIGAKQIQKYVPWHSRTPALGA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JS37-1", "uniprot_id": "NHLC3_HUMAN", "id": "Q5JS37-1", "name": "NHL repeat-containing protein 3", "aln": "--------------------------------------------------MARFWVCVAGAGFFLAFLVLHSRFCGSPVLRNFTFAVSWRTEKILYRLDVGWPKHPEYFTGTTFCVAVDSLNGLVYIGQRGDNIPKILVFTEDGYFLRAWNYTVDTPHGIFAASTLYEQSVWITDVGSGFFGHTVKKYSSFGDLVQVLGTPGKKGTSLNPLQFDNPAELYVEDTGDIYIVDGDGGLNNRLIKLSQDFMILWLHGENGTGPAKFNIPHSVTLDSAGRVWVADRGNKRIQVFDKDTGEWLGAWNNCFTEEGPSSVRFTPDGKYLIVAQLNLSRLSVVAAPPVGSIGECSVISTIQLADQVLPHLLEVDRKTGAVYVAEIGAKQVQKYVPLNSYVPSFGS", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ***:*** ***: ********** * *.*:* :*** *. *:***:****:.*****:**************:.****:***:***:******************:*.:.* :************ :*******.*:***************.**************:***::*************:***********:*******************:.************:**************:*********:*******:*************:: *** ****:*:*:*******:************************:***:* :* .*::*:", "identical_positions": 284, "similar_positions": 49, "identity": "71.54%" }, { "cls_id": "homologset.agr.MGI:2444521", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZSG1-1", "uniprot_id": "ARK2C_HUMAN", "id": "Q6ZSG1-1", "name": "E3 ubiquitin-protein ligase ARK2C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLVHVGYLVLPVFGSVRNR----------GAPFQRSQHPHATSCRHFH----------------LGPPQPQQLAPDFPLAHPVQSQPGLSAHMAPAHQHSGALHQSLTPLPTLQFQDVTGPSFLP---QALHQQYLLQQQLLEAQHRRLVSHP-------------------------------------------------RRSQERVSVHPHRLHPSFDFG-QLQTP--------------------------------QPRYLAEGTDWDLSVDAGLSPAQFQVRPIP------------------QHYQHYLATPRMHHFPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVR-------------------ESYEELLQLEDRLG-------------NVTRGAVQNTIERFTFPHKYKKRRPQDGKGKKDEGEESDTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGADS--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QAU8-1", "uniprot_id": "ARK2C_MOUSE", "id": "E9QAU8-1", "name": "E3 ubiquitin-protein ligase ARK2C", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLVHVGYLVLPVFGSVRNR----------GAPFQRSQHPHATSCRHFH----------------LGPPQPQQLAPDFPLAHPVQSQPGLSAHMAPAHQHSGTLHQSLTPLPTLQFQDVTGPSFLP---QALHQQYLLQQQLLEAQHRRLVSHP-------------------------------------------------RRNQDRVSVHPHRLHPSFDFGHQLQTP--------------------------------QPRYLAEGTDWDLSVDAGLSPAQFQVRPIP------------------QHYQHYLATPRMHHFPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVR-------------------ESYEELLQLEDRLG-------------NVTRGAVQNTIERFTFPHKYKKRRPQDSKGKKDEGEESDTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGADS--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BE56-1", "uniprot_id": "A0A8M2BE56_DANRE", "id": "A0A8M2BE56-1", "name": "RING-type E3 ubiquitin transferase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLVHVGYLVLPVFGSVRNR----------GSHFNRHQHSHATSCRHFH----------------VGP--QAQIPVDFPMPHPGQSQTGMSHHLGPAHQPTAALHPSLNHIPAPPFQDIPAPPFLP---QALHQQYLIQQQILEAQHRRILPQPS------------------------------------------------RHAPDRTLPHPQTLRPPYEYPPSIHIPP---------------------------PVPQQPRYLAEGTDWDLSVDPGLP--QYHISPLT------------------QHYQHYLTSPRLHHFPRNTTSAQVVVHEIRNYPYPQLHLLALQSLSPSRHATAVR-------------------ESYEELLQLEDRLG-------------NVNRGAVQATIERFTFPHKYKKRRPLELKIGMDE-EELDTDEKCTICLSMLEDEEDVRRLPCMHLFHQACVDQWLATNKKCPICRVDIETQLSPDS--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M6YUK5-1", "uniprot_id": "A0A8M6YUK5_DANRE", "id": "A0A8M6YUK5-1", "name": "RING-type E3 ubiquitin transferase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLVHVGYLVLPVFGSVRSRGCMDSLSSRTGAHFSRHQHSHATSCRHFH----------------LAAT-ATPLPADFPPP----------------------------PLAPPQYQEVP-PPFLP---QALQQQYLIQQQLLQR----------------------------------------------------------RRTQERVPLNTHRLRPGYEYAPPLHVPQ---------------------------PIPQQPRYLAEGTDWDLSVDAGVLH-QYPLQQIP------------------QPYQHYLASPRMHHLPRNTSTTQVVVHEIRNYPYPQLHLLALQSLSPSRHSSAVR-------------------ESYEELLQLEDRLG-------------SVSRGAIQTTIERFTFPHKYKKRKPLDLKFCEND-EESDVDEKCTICLSMLEDGEDVRRLPCMHLFHQACVDQWLATSRKCPICRVDIQTQLSPES--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KFN6-1", "uniprot_id": "A0A0B4KFN6_DROME", "id": "A0A0B4KFN6-1", "name": "RING-type domain-containing protein", "aln": "MDSLENDQEELHHQPRVTLAYGSVATSSGGQENHSQYAMYYNQQRDSEGYMLMTPFLSSSQSHSHTRSPPTYTAMVEPRREESSGFEGLARRCDKCSSLDGLCRCESMVASSSRYADSTQNQSHSEAQFLEQPSSSTAAIANPPAVHSIPRPKRKKTEPLTMEPESDNDGDAVVASVSGTWPAGAIEEHAMDSTAVVYEVPSSSLQLSNSSFETAPSAVNAYDDVTSSASDTEHGQFAHTRTTNTTTTTSAVQAHKKKASRSNNASNTSSRAVDTDATPSTSAQSRKRQMSQFSYRKSRVLEPENESSDDGWDLRVHNPVPPIEPTVTIIRGSRGSDEAEIGHTDHNYYNSRCAVAGAPPDSTYIRSASCSTATHTTRSVDYGSRIGRRSAATGSPSTSSDQEQEQQQRQQQEEIIHEERRHQQSPGQPMHSMYGVPGESRMSWSRARPSDDSVPPRKHARMELPGRSRSKLSSTNFNSFYPGRRGHRTFAEQGNSSGQHHVRFPPSSTPNSNGPCVITYVGRPRDSQPAADLNLPSTSTGRRGSHETRADSVVLTAPDLQLDDWSSDDDDDDVVFVHSTREPILSIDLTSDDDGLANDTQLQRDRDRGRERERERARDREPYRNDTQPNPEDPNEDRRTMYDCAYTFPYARRTDRRTEANNEGTSAFAFYSGALADRAAISDHNYSYELDQLMDPGPGNFYPPRCSNMDPQRYFLPINESSMWMPGHPAPPPPPPPMPPILLPDNSSTEAYLRHQQRNLTSTPSSSSSEQTSTQQSRHRRSSPANVYHRYHPYYYAITTLPTVVESDYPPSLQPHPHPHPHFQPSQGGSSRSSLSGALNAAAVAATAAAVQAQTFSDLLSQAHNEGRAAALEGNRTPPHTMVHAQHQQRQSINPPAPGVASNANLAAAVSPPPPLEMYSGRSTIPHCGSPPFSVRRSEAAYSNRQHYQPQPHQGHQAPQNQMHAHIHPPHRASAIVATSLTPAPPYPVHQNLWYRQQSMQEMHRRHMTPTPIDLSSNAPLLTSTLRNGYLHSICSCVHARNGPVSSLDPAYYPPYDAAPAAAAPPPSPQQQSPATSGSGNSSVAAQASMRHLQLQPQQQPQAQQSPPVMQHMQRQRAIHHHMFHHHYSPLHLEIGLAPLSLGSRILIAPSRPNRGATLETIERNTLPHKYRRVRRPS--------ETDEDAEKCAICLNLFEIENEVRRLPCMHLFHTDCVDQWLVTNKHCPICRVDIETHMPNDALPPSSSGVPDAANSAALXHCVHGIFM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* . . : . *. : .: :* :::... :* . . .* . : . :.:: .. **. : : ::. .: : : * : :: * * * *** :. : : * * ::* * .. . .. * . . : *.*.::. * : . : . *:** *. .*** **** *:****:: : . * : ***:***.::* ::*********** ******. .::********:*:: :: ", "identical_positions": 72, "similar_positions": 90, "identity": "5.66%" }, { "cls_id": "homologset.agr.MGI:2444524", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UEG4-1", "uniprot_id": "ZN629_HUMAN", "id": "Q9UEG4-1", "name": "Zinc finger protein 629", "aln": "MEPETALWGPDLQGPEQSPNDAHRGAESENEEESPRQESSGEEIIMGDPAQSPESKDSTEMSLERSSQDPSVPQNPPTPLGHSNPLDHQIPLDPPAPEVVPTPSDWTKACEASWQWGALTTWNSPPVVPANEPSLRELVQGRPAGAEKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQSTNLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQATHTGEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTHTGERPYKCPECGKSFSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFIRSSHLIQHRRTHTGEKPYKCPECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAHELEQHRVIHERGKTPARRAQGDSLLGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKNADGLIAHAAPKPPQLRSPRLPFRGNSYPGAAEGRAEAPGQPLKPPEGQEGFSQRRGLLSSKTYICSHCGESFLDRSVLLQHQLTHGNEKPFLFPDYRIGLGEGAGPSPFLSGKPFKCPECKQSFGLSSELLLHQKVHAGGKSSQKSPELGKSSSVLLEHLRSPLGARPYRCSDCRASFLDRVALTRHQETHTQEKPPNPEDPPPEAVTLSTDQEGEGETPTPTESSSHGEGQNPKTLVEEKPYLCPECGAGFTEVAALLLHRSCHPGVSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6A085-1", "uniprot_id": "ZN629_MOUSE", "id": "Q6A085-1", "name": "Zinc finger protein 629", "aln": "MEPETVLWGPDLQGPEESQNEAHRGAGSGNEEESPQQESSGEEIILGDPAQSPESKDPSEMPLESPSQDASAPQDSPTPLGSS-PLDHQTPMDPSAPEVVPSPSEWTKACETNWQWGTLTPWNSTPVVTASEPSLRELVQGRPSGAEKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQSTNLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQATHTGEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTHTGERPYKCPECGKSFSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFIRSSHLIQHRRTHTGEKPYKCPECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAQELEQHRVIHERGKTPARRAQGDSLLGFGDPALMTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKNADGLITHPAPKPQQLRPSRLPFGGNSHPGASESRADPPGQPSKVPESQEGSGQRPGQPSPKCYVCSHCGESFLDRAVLLQHQLTHGNEKPFLFPECRTGRGEGAGPSPFLNAKPFKCPECKKSFGLSSELLQHQKVHAGGKS-QKSSELGKSSSVLLEHLRSPLGARPYSCSDCGASFLDRLALTRHQETHTHERASTPEDTPSESATLSTNQEDEGEASTPPKSSSHGEEESPKTVSEKKPFLCPECGDGFTEVATLLLHRSCHPGVSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99PJ7-1", "uniprot_id": "ZN689_RAT", "id": "Q99PJ7-1", "name": "Zinc finger protein 689", "aln": "---------------MAPPSAPLLEQAPGEVGPTRRRGRRPRALKFADVAVYFSSEEWGRLRPAQRTLYRDVMRETYGLLGAL-----------GCAGPKPALITWLERNTDDWEPAALDPQEYRRWVTFQR-KTRTRQKNEEKEVFPPKDVPRKGKRGRKPSKPRLIARQTSGGP--ICPDCGCTFPDLPALESHKCAQNLKKPYPCPDCGRRFSYPSLLVSHRRAHSGECPYVCDQCGKRFSQRKNLSQHQVIHTGEKPYHCPDCGRCFRRSRSLANHRTTHTGEKPHQCPSCGRRFAYPSLLAIHQRTHTGEKPYTCLECSRRFRQRTALVIHQRIHTGEKPYPCPDCERRFSSSSRLVSHRRVHSGERPYACEHCEARFSQRSTLLQHQLLHTGEKPYPCPDCGRAFRRSGSLAIHRSTHTEEKLHACDDCGRRFAYPSLLASHRRVHSGERPYACDLCSKRFAQWSHLAQHQLLHTGEKPFPCLECGRCFRQRWSLAVHKCCPNTHNGSPRPLIGGPNQRSSAL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : : :: . : :.* * .*:: .: : .. ::. ** .. *: * : .*: .:* . : *. .. . * :.. . * . ** : ** * :* *.:** :*.: . * .*: ::. :*** *****: **:.* **.*:*:*:** ** * :* * *:* .** :** *******:* :* *.* ** .* :*::*******::**.**:**. * **: *:***** * **.: * * : *. *** ******* * :* : *. ** *:.*:*.* * *: * * *: :***:** ****:** **:**::* *..* *: * *: : * ***: * .* * *:*:*:**:** *. *.* * : *** **: ******: * ***:.* * .* .* .* . * . .: * ", "identical_positions": 181, "similar_positions": 125, "identity": "20.83%" }, { "cls_id": "homologset.agr.MGI:2444525", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AN36-1", "uniprot_id": "A0A8I6AN36_RAT", "id": "A0A8I6AN36-1", "name": "", "aln": "----------MESFIPVDLPVQKPDVNEKE----RNSRRRHLLYKDRRLIQNRLAKAK---TSSESLISEG-ADDQDYYPDY-LEQKFSRQCVVGSKPFLPDIKKAKEKPEKTARVRR-KWPQVTLYDSTEPKETDAVKHIIRLREKLEWENPSFPRSLKYSPKITAPKHTLKACLKDDGEFIYCLPLENT----RGMFNEYDLQAVSAHKAKNCKVFWMVSASFVSKIT---KTGVNTEEVELIPTVEWLSERHYFYLLLQFKIFYNFR-----INKAFVTWKLNVKRQKTESSRSYLYSHLFSADELFQTSLLYVRGLCEDALTLKKNKKD--NPSAICLIKVDTSRTYSLEKFCEEQLQQATQAVVQLEEMRSKAIVEIKSTALKVAEKKDVKEYFESKPAEIDTTHFKLPQYRCLLETNMKFLKLIDYLFQELIRQLMNSALNQLLDLFTHSARTPFSKERRNESLMR---DRKIFSRKISDDGEFVH--SRLTA---QDSELKQDTNVNETSNRHTAKTDLKKAYAAIFEISFCLRTPTVSDSPEDLEENTQKTKQSREESLMYEEEQENRVRTVSEDLLSQYYQPSKFGVLLKRILSDTGLLLESEQERFYNKLSEFPTNLFMEPNRLDFSTQFQNMIAAIEKYITTLVPLQRDPRLSTLVDLVSVPDLSNQTKGR--VKYKKHAQWPDYYILFDTDADYQNKIVSLLALIGNSVGLVSGYSYRFLKYCYMVEKAKVMCTKLPLMMNLTSIEFKNIIHKFRSYLKQIVTMAVEMRLGIFCVKTLDYQLACLPYVDSIIQMSYNLLRCTIEDRSANLLEILESSLRQLDAEPIEVEQFVEHFNFLDEISSSVTQIEKDFCTITELYSVVRHYHVDISEEQIAIYKIIFMKFNYLKTSVKLVATSKEANLTKFRDSLEAYIVSLRVDVSNLKDKIRSPILLSTSTPVQQAKDIIQSLSAETESLTLKVKTYSTYQDYYDYAHFHMNALNVDEFTQLVMTEISDIECDLMLRKLLWEAQEEWGTYFWEWRNCTLQGIDIDVVKNNVSKWLHIIIVLEKGLPKNDMVALLKQSVLDFKQELPIITALGNPYLKARHWEALQEITGKSISLDKSLSVEKLLALKMFPYEKKIIEISVSATNEASLERMLFKVIELWNTSPLHLVPHITDGRSILIISSTDDLIAQLEDSQAILSTIKGSSYLRPIKHLVNEWNQNLTLFSQTIDEWMTCQRNWLSLEPVFQSLEIQKQLAAETKIFSQVLLTWREIMSRVLNKLNALHITITTGILDSLKSCNGHLESIKKSLEEYLELKRMNFPRFYFLSNDELLDILANSRDPESVQPHLVKCFENVRHVLLWKQGIGPPSVKMLISAEGEGLVLPKKIRVRAAIEQWMVNVEKSMFDVLKKFITQGIEDWKFHTFSDWVMSHPGQVVLTVSQIMFYNDCLKGFMSYNPREKLEAVHARVLHQLDDIAMLVTQNTSNLRTKTMLAATLIIYVHCRDILTDLLVKNIFNMQDFEWCRHLQYKWNEKQKLCYVLQANTSFVYGYEYLGCAPRLVITPLTERCWLSLSEALYFNLGGCTAGRAGTGKTETVKDLAKSFGKHCVVFNCFEDLDYKIIGKLFFGLVQSGAWCCFDEFNRIDIEVLSVIASQILMIKDAKDSYSVRFLLDGREVRINMSCAVLITLNPGYRGRVELPSNLKSLFRSVAMMVPHYKMITEVTLFSFGFKSSKSLSGKIVSLYDLADKQLSKQEHYDFGMRTLKTVLIMTEKKKLEHKCTVGEHLSELEESLIIIEAIQEASMSKFLPEDVLPFERIIEDVFPGITVSKTQHLALEKAIHSATEQLGLQQWPPQKAKIIQFYKQLQACVGVILVGPTGGGKTTVRKILEKALITLPVTSALPIKERQSDSKSTGKKGKVDVCVLNPKCITLGELYGQLNINTMEWNDGLLSAAIRNYVHINTTDYSKKGSDLGMSG-VTDLSNIFQVSFSTIADMDNNIFMNKLEKSFKTPETYDFDWQWIVLDGPVDILWIENLNTVLDETRTLCLANSERISLTNKIRLVFEVDTLFNATPSIVTRCAVVYMDPVDLGWEPYIKSWLLRTSKSLNQQGMQCLEIMINKSVDEGMKFLKKHKKFLPCPIQEVTVVMTLCRILDAFFEFMHIKRETPKSHEATDNGSPTETKALRVKFKEEKSYNKDERTWFLERNPEKLPLMIQKIFVFAFTWAFGGILKREDQHEEDLLFRSDFEHDSPAEVTYNFDNFAREVFEDDSDKGIGIRLPGSEQSIFGYFVDLQQCEFMPWSDLVPNAQTLIQKGTSVLTDFQRSGENVLRMKEYGEYVNYTATRDTVCLSFLMSLLLRNSCPVLLTGDCGVGKTTAINRMLEKLEGQGTFDIKYGSILGKVLLHNEIKRSSLRQNINVLIGETGKVVGVGLDQGAKTEEDKGDDDSTVKNDKGIIVSTVNFTTTMTAAKTKELILQKLVRKTKDILGAPKNNRIVVFIDDLNMPLPDECGAQPPLELIRQLLDMGGIYDTERNVWKSIQDLSLIAACTPSAGGKDISPRLLKHFSVLVLPHPPQSVLCTVFQAHLGLYFSLHNFVTEVQKCRDQIVFCSLAIYYEVCKKMLPTPTKCHYIFNPRDMFKLLLGLMQADKSVINSKETVALLLVHEASRVFHDRLIEPKEKSLFYQILSTELQNHMQVSWSQESLMNNPVLFVDFMDVNKPHRKRIYQNTDNYDKLLNILTEFQQKLGSTSLEMSHSVVFFKEAIEHITRTTRVLRQPGSHMLMIGMDGCGKETYGTIACYVAEYKICKVPISHNYAISEFKEMLKKVFIQAGLEETPTVVMVANLLEEHVSFLEDLNYIINAGKISNMFENEELDSIVMRVRTFAEQSSCMDDRKYLLSLFQKRVSKNLHVCMMCTT-GPNFRHSCRVYPSMISSCTIDWFQRWPDEAFLIVANSYLEEKLNVENKENKIRQFAPTCVEIHKSMKDLSIKYFEETGRHYYITPSCYFKFLETFTHSLRVRQEEMQTKRNRFYMGLSKILEATALVTDMQEELLVIGPQIEQKAKEKEILMEKLRKDSQIVEKVQVLVKQDEEIVAEQVKIVEDYAQKTANELKSVLPSLDKAIVALNALDKSDISELRVYTRPPYLVLTVMNAVCILLEKKPNWTTAKLLLSDTSFLKRLINLDKDSIPDKVFLRLKKILNLPDFNPSKIAMVSVACCSMCQWVIALNNYHEVQKVVRPKQAQVAEAQNVLQIAKQRLFEKQRGLQLIEEHLQFLHTSYRDIVTEKHQLANRKKLATKRLQCASVLLTVLEDEKIRWQETINEIDNKLKGICGDIFLSSACLAYSGVLTPEFRQLVMQKWKDFCTQAEIILSPNFSLIDVMAEKNEIRRWHNQGLPLGQHSAENAILMKSTKQWPLLIDPHKQALCWIRQMEGSRLQEISAQDSNYTKKLVFAMQSGDSVLLQNIPEMFPPTLRAMLKKDICQTRGQSYIRIDDTEIEYNEKFRLYLSTELENPHFFPSVYNFVTIINFTVTFQGLQDELLSTVVSHEVPHLENQRAQLLESISLDAITLEELEDKTLTLLQKTEGSVLDDEEIVETLRKSKITSNEISKRIKKTEKAESEIQATRKNYLPIATRGALLYFVVASLRQVGYMYQFSLEWLRKVFVSSTVSKTKDEKPDWKTDDTSQEKVDEVSLSPSDQENLESERTPLAENIKNVIDTLTRNVFKVVSSALFNEHKLCFSFRLCTTIMRDHSSDTLTADDIGFLPEEEWNIFLYTGILINIKNIFSKPRLNSIFEIRRKEHLQWVLDLRWRQCQYISNQMESFSLLCKSLLSNEQQWNAFRDSKAVYSLLSLPFFSDEPSLQKTPRSAKEAELLDENDEMLHPITFPWEKLTQFQRLILIKILRPDRLESSIKKFITEKMGSEYIPDTTINLKESFSESTAQTPLILTCSYGIDLNNLLLRFAQEFKGTTPQVTMISLGRDQATKAEQLIFKAVKKKHQWVFLQNCHLAASFMPRLTAIIDSFSSPDMVLDPDFRLWLSSRAYGFFPITILQKGVKIAVEPPQGLKSNLLQMFGYGGSGEVTEEVFDKPDCGPWWKKILFSLCLFSAVLNERKAYGTLGWNIPYQFSSSDLEVSIKVLANVLSGQSEVPWKEVNYLISEVTYGGRVTDEWDKRCLKALFYKFCNPEILKDNFSFSSNVMYQAVPSSASLKDCISIIQSFPDDDSPEILGIHPEATYTCNEIKAQKYIENLICMQPKDAPGTPMINPEQSNDDLVMEILSDIMMQLPLTVENEEVSGLENQCTFKFIMSSPMWEKLHENIQGYDPLIHSVLIPFLKNEIERFNKLLSVIHKSLKDLQLSIKGESILTPDLEETYDSFLRARVPMLWQKNAYKSCRPLSFWVSNLIQRVNFFNTWAKVAYTTIHHRYMMFITTWKR----LGQKSKHYPDSGSEVTEGFPARYWLSAFFSPQAFLTAVLQDYGRAQGISMDALTFTHKVIYNSDGSQEDDLSKFLQKRLNIVKRAFQQHQEHHHEGVYIFGLYIEGARWDPQQEVLEDALPAQLCCEFPDIHFLPTKITEIPE--DSDQ--SELQTFECPVYYTPERTR--NATGLPTSLLTSVHLPTKKPPSHWITMQVALLCEKNE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A571BGC3-1", "uniprot_id": "A0A571BGC3_MOUSE", "id": "A0A571BGC3-1", "name": "", "aln": "----------METFIPIDLTVQKPNVNRKD----HKSRRRRSIHKGRQCIHGRSAMAVGKKIPSESSSSEGTEDDQDYRPGY-LEQKFSPQCVGVSKPFFPDIRNAKVKPEQTAHTTR-KRSRIQPYDRAEPEEADAIKHIFRLREKLGWETPSFLRSLKYHPKTVLPRCSLKECLKDDGEFIYCLPMEND----RGMFNEYDLQAVSAHRAKSCKEFWMVTASFVSKIT---KTGLNMEDVELMPTMDWLYERHYFYLLQKFKIFYNFR-----LNKAFVTWKLNVKRRKTETSRSYLYNHLFCADELFQTSLLYVRGLCEDALTLKKKNKD--NSSTICLIKVDTSRTHVLEKFCEEQLQQATQAVAQLEEIRSKAIVEIKKSALKVAEKKNVKEYFESKPSEINTTHFKLPQYRNLLETNLRFLKLIDYLFQELIRQLMNSALTQLLDLFTGSARMPFSKEKKNESLMR---DRKIFSRKESDDDEFVL--SSLTAPSFQSSQPKLDTDVKETFNSHRVAMDLKKTYAPIFEISLCLRLPTMNDSPEDLEGNNQKSENCEESLVCDEEELENRKRTSSEAMLSQYNQPSKFGTLLKRILSDSGLQLESDQERFYNKFFEFPTNLFMEPNRLDFSTQFQNMIATIEKYVTTIIPLHQDPRLSILVDLVSVPDLSNETKTKSVVKYKKQTRWPDFYILFDTDTDYQNKIVTLLTIIGNSVGLVSDYSCRFLKYCYIVEKAKVMTTKLPFMTNLTSIEFKRIIHKFRSYLKQIVTMTIEIRIGIFYVNSLDYQLACLPYVDGIIQMSYNLLQCTIEEKSANLLETLDSLLHQLDTEPVELEEFVEHLNFLDDIFSSLTEIEKDFCTISELYSIVRHYQINVSEEQIAIYKIIFMKFNHLKTSMKFVAMNRETSLTKFKNGLEAYIVSLRVDVSNLKDKIRTPLLLAASTPIPKAKEIVQSLEAEAESLTLKVKTYSNYQNYYDQAYFRMNAINTNEMSHIVLSEISEIECDLMLRKLLWEAQEEWGKYFWEWRNCTLQSIDIDLVKNNVSKWLHIIIVLEKGLPKNDMVPLLKQSVLDFRQELPIITALGNACLKARHWETLQGITGRSTSLNKNLSIEKLLALKLFPYERKINEISISATNEAALEKMLFKIIDLWNTTPLHLVPHLTEGRSILIISSTDDLITQLEDSQAILASIKGSSYLRPIKQLVIKWNQNLTLFSQTIDEWVTCQRTWLSLEPIFQSLEIQKQLAAEAKLFSQVLVMWKEIMSRVLNKLNALHITISTGILGVLKSCNSHLESIKKSLEEYLELKRMSFPRFFFLSNDELLDILANSKNPESVQPHLVKCFENIRRILLWKQDVGPPSVKMLISAEGEGLVMPKKIRVRASVEQWMVNVEKSMFDVLKKFIIQGIEDWKYHTFSDWVMSHPGQVVITVIQIMFYNDCLKGFMSYNPREILEAVQARLLRHLEDIAVLVTLNTSNQRTKTMLAATLIICVHCRDIMSDVLVKKIFSIQDFEWTRHLRYKWNGKQKLCYVLQANTSFVYGYEYLGCAPRLVITPLTERCWLSLSEALYFNLGGCTAGPAGTGKTETVKDLAKSFGKHCVVFNCFEDLDYKIIGKLFFGLVQSGAWCCFDEFNRISIEVLSVIASQILAIKIAKSSYSVRFVLDGREIRINMSCAVLITINPGTTGRVEIPDNLKYLFRLVSIMVPHYKMITEVILFSYGFKSSRSLSGKIVHLYDLADKQLSKQEHYDFGLRTLKTVLIMTEKKILEHKCGRGEHLSELDESLILIEAIREASLSKLLPEDVLPFEKIIEDVFPRITVSKINHLTLEKAISTATEQLGFQHWPSQKEKIIQFYQQLQVCVGVILVGPTGGGKTTVRKILEKALVTLPVTSAMLMKERQSDSKSTGKKGKVDVCVLNPKCITLSELYGQLNINTMEWNDGLLSAAIRNYVHMNTADYSKIDNDFEMSG-ITDLSNIFQVGFSTIADMDNNIFMGELEKSFKTPEIHDFDWQWIVLDGPIDSLWIENLNTVLDETRTLCLANSERISLTNKIRIVFEADSLFDATPSVITRCAMVYMDPVDLGWEPYMKSWLLKSSKSISQQGIQCLEMMINRSVTKGMKFLKKHRKFLPYPIQDVTVVITLCRILDAFFEFMHIKQGTPKSHEAMDSESPTETK-VKVKFKEETSHHKDEGSWFLERNPEKLPMMIQKIFVFAFTWAFGGILKREDQHEEDILFRKSFEHDSLAEVNYNFDIFVREVFEDDSERDTGISLPGSERSVFGYFVDVQQCEFMPWSDLVPTAHTLIQKETSLLTDFQGSSENVLRMNEYGECVNYMATRDTICLSFLMSLFLRNSYPVLLTGDCGVGKSVAINKMLEKLEGRGTLNIKYGSILGKVLLHNDIKRSSLRQNINILIGDPTKIIGAGLEQSAKKEEAKAN-DSTVINDKGIIVSTINFTSTMTAAKTKELLLRKLVRRTKDILGAPKNNRIVVFIDDLNMPIVDACGTQPPLELIRQLLDMGGVYDTERNMWKSIQDLSLIAAYTSSVSGKEISPRLLKHFSTLVLPHPPQSALCTVFQAHLGMYFSINNFVNEVQKCRDEIVHCSLAIYYEVCKKLLPTPTKCHYIFNPRDIFKLLLGLMQADKNIINSKEMAALLLVHEASRVFHDRLTDQSEKSLFYQILSTELQNHLQIYWSHERLMNKPVLFVDFMDINKPHRKRVYQNTDNYNELLSILTKFQQKLSSSSLEMSHSVVFFKEAIDHITRTTRALRQSGSHMLLLGIDGCGKETYATIACYLAEYKVCKVPISHNYAISEFKEMFKKVFIQTGLEETPTVVMVTNLQEEHVSFLEDLNYIINAGKISNMFENEELDSIVMRVGTFAEQLTCIEDRKYLLSLFQRRVSKNLHICMISAT-GPNFRHNCRVYPSMISSCTIDWFQRWPDEALLVVASSYLKEKLKVEDKEDKIREFAPTCVEIHKSMKDLSAKYFEETGKHYYITPSCYFKFLETFTHSLRIRQEEMQTKRNRFYMGLSKILEATVLVTDMQEELLVIGPQIEQKAKEKEILMEKLRKDSQIVEKVQMLVKQDEEIVAEQVKIVEEYAQKTSNELKNVLPSLDKAIVALNALDKSDISELRVYTRPPYLVLTVMNAVCILLEKKPNWATAKLLLSDTSFLKRLINIDKDSIPDKVFLRLKKILNLPDFNPNKIAMVSVACCSMCQWVIALNNYHEVQKVVRPKQAQVAEAQNVLQIAKQRLLEKQRGLQLIEDHLQFLHTSYRDIVTEKHQLASRKKLATKRLQCASVLLTVLEDEKIRWQETINEIDCKLKGVCGDTFLSSACLAYIGVLTPEFRELVIQKWKDFCTRAEIILSPNFSLIDVMAEKNEIRRWHNQGLPLGQHLAENAILMKRTKQWPLVIDPHKQALHWIRQMEGPRLQEISAQDSNYTKKLVIAMQAGDPVLLQNVPETFPPNLRAMLKKDVCQKRGQYYIKIDDTEIEFNKNFRLYLSTELENPNFFPSVYNFVTIINFTVTFQGLQDELLSTVVSHEVPHLENQRAQLLESISLDAITLEELEDKTLTLLQKAEGSVLDDEEIVETLRKCKMTSNEISKRIKETEKAESKIQATRKNYLPIATRGALLYFVVAGLSHVEKMYQFSLEWLRGVFVSFTVSKTKEEKHDWKTDETSQEKADEVSLSSSEQENLESERIPLAENIKNAIETLTRNVFKVVSSALFNEHKLCFSFALCTTIMRGNSSDTLMADDIGFLPEEEWNIFLYTSILINIKNILSKPRLNSIFEIRRNGHLQWVPDLRWRQCQYISNQMEPFSLLCTSLLSNEQQWNAFKDAMAVYSLMSRPFFSDAPLPQKKPRSAKEAELLDESDEMLDPVTFPWEKLTQFQRLILIKILRPDRLENSIKKFITEKMGGEYIPDTTVNLKESFSESTAQTPLILTHSYGIDLNNLLLRFAEEFKGTTPKVTMISLGPDQENKAEEIIFKAVRKAHQWVFLQNCHLAESFMPRLTAIIDSFSSPDMVLDPDFRLWLSSKASGFFPITILQKSVKIAVEPPQGLKSNLLQMFGYGGSGEVTEEMFEKPDCGPWWKKILFSICLFSAVLIERKAYGTLGWNIPYRFSSSDLEVSLKVLGNVLSGRSEVPWKEVNYLISEVTFGGRVVDEWDMRCLKTLFDKFCNPEMLKDDYSFSSNEMYQPVPSSASLKDCINIIQSFPDDDSPEILGIHPEATHTGSEIKAQKYIENLIYMQPKDAPGYLMIKPMQSNDSVVMEVLSDIMSQLPLTVESEDVSEPGLQSTFSFIVSSPIWERLHENIQGYDPLIHSVLIPFLKKEIERFNKLLSVIHKSLKSLQLAIKGESILTPDLEETYDSFLRARVPMLWQKNAYKSCKPLSIWVSNLIQRVNFFNTWAKVAYTAIHHRYMLFITTWRQ----LGQKSRHPTDFKTEITDGFPARYWLSAFFSPQAFLTAMLQDYGRAQGISMDTLTFTHKVIYNISVTQEDDISKLLQKRLNIVRRAFQQHQDHSPKGVYIFGLFMEGARWDPEQEVLEDSLPSQLCCEFPDILFLPTKITEPSASQDSDQTASDLQTFECPVYYTPERSR--NMIGLPTTVLTSVHLPTKKPPSHWITMQVALLCEKNE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0VDD8-1", "uniprot_id": "DYH14_HUMAN", "id": "Q0VDD8-1", "name": "Dynein axonemal heavy chain 14", "aln": "MGRRSQWIWAMRCQMLVPVLSLHIGLARALGCGCIASKIECLIRCNAPFPLLDAVGSVASQELQSLTGTVGVTSGAAAYPRWNLARARAPPHLPGTQDPLRRVRDPTPIVASSPGRRRGSWSGGYGQEASEPGVVGLCCAVLPIHPSLALAGVGGPDLRRFQEGPQRPSDHGAAEKHMETFIPIDLTTENQEMDKEETKTKPRLLRYEEKKYEDVKPLETQPAEIAEKETLEYKTVRTFSESLKSEKTEEPKDDDVIRNIIRLREKLGWQTILPQHSLKYGSSKIAIQKITLKKPLEDDGEFVYCLPRKSPKSLYNPYDLQVVSAHTAKHCKEFWVITASFISKLDSSRTYSLDEFCEEQLQQATQALKQLEDIRNKAISEMKSTFLKVAEKNEIKEYFESKLSEDDTTHFKLPKYRRLLETFFKFVMLVDYIFQELIRQLMNTAVTLLLELFNGSAGMPFSVEKKNENLIRTFKDNSFPTGKTTNDCEELVDNSKLHAISVQKSEVKTDTDINEILNSVEVGKDLRKTYAPIFEVNLCLRIPAESDSSENSKENFHESDQCPEECVMFEDEMSENKDNCVKKHSSEELLP-------------------------------------KAKKSKEISYNLEDIIS------ATITPLCQDPQLSIFIDLVSIMDLPNKTGSI--IHYKEQTRWPDCHILFETDPAYQNIIVNLLTIIGNSMGLVNAYSHKFIKYCTMTEKAKIMSMKISSMGELTSKEFEAILNRFRNYFRHIVNMAIEKRIGIFNV-------------------------------------VVESSLQQLECDPTEIEEFLEHFIFLNAISSKISKLEKEFLTMSQLYSVAKHHQIHISEEQIAIFQVLLLKFSQLKSSMKLSKINKDTAITKFRDNLEACISGLHVDVGNLKAKIRTPLLLCAGTQVSTAMEMIQTLSGEAASLTNKAKAYSHYQDCFSDSQSHMHSVNVEEITQIVLSEISDIEGDLTLRKKLWEAQEEWKRASWEWRNSSLQSIDVESVQRNVSKLMHIISVLEK------------------------------------------------------------------------------------------------------------EIYSIFIIPSIDDISAQLEESQVILATIKGSPHIGPIK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQIMFYNDCVKSFVSSYSREKLEKVHAGLMCHLEEVADLVVLDTSNSRTKAILGALLILYVHCRDIVINLLLKNIFNAEDFEWTRHLQYKWNEKQKLCYVSQGNASFTYGYEYLGCTSRLVITPLTDRCWLTLMEALHLNLGGCPAGPAGTGKTETVKDLAKCALFAFKCNTALIKLPNSLIVLTCFGLEKT--------------------------VLVMNTVMSFRFVLEGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPHYQMIAEIILFSFGFKSANSLSGKLTNLYELARKQLSQQDHYNFGLRSLKIVLIMAGTKKREFKCDTSDSLSEADETLIVIEAIREASLPKCPPEDVPLFENIIGDIFPEVTVLKVNQLALEKVIYTATQQLGLQNWSSQKEKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRILEKALTLLPIADFLSVAERKSASKISERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTDGLLSATIRSYVYFNTPKNTKKDIDLRLKSRISDLSNVFKLDSSDTTETDDNIFE-EIEKVVKIPENHNFDWQWIILDGPVDTFWVENLNSVLDDTRTLCLANSERIALTNKIRVIFEVDNLSQASPATVSRCAMVYMDPVDLGWEPYVKSWLLKTSKIISQSGVDCLEFMIKNSVTDGLQFIRNRQKFQPYPMEDITVVITLCRILDAFFDFMGKNGGFEQSDDLNDTSS-KEANSQRESVTFKDIEKRDENTWYPEKNPDKLTKIIQKLFVFAFTWAFGGALNREDEHRENIPFCPSLEPDSLAKVTYDFDKLVHELFGNSSQ--VGINLPTGECSIFGYFVDIEQCEFIPWSDLVPNDQTLIQRD------------------------------------------------------------------------------------------NPTKKPEVRTNKKLLKNN---------------------------DHKGVVVSTINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPVSDMYGAQPPLELIRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPVVN--DISPRLLKHFSMLVLPHPSQDILCTIFQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHAGLKGKPTVLMVPNLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHMDNRQSLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEEALLIVANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNSYLQFMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKETETLMEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVALNALDKADVAELRVYTRPPFLVLTVMNAVCILLQKKPNWATAKLLLSETGFLKKLINLDKDSIPDKVFVKLKKIVTLPDFNPHKISLVSVACCSLCQWVIALNNYHEVQKVVGPKQIQVAEAQNVLKIARQRLAEKQRGLQLIS-----------------------------------------------------------------------------------------------------------------------RWHNQGLPHGQYSVENAILIKNGQQWPLLIDPHRQAHKWIRQMEGSRLQKLSIEDSNYTKKIENAMKTGGSVLLQ-----------------SCQAS--------------TWRKKLYLSTEIDNPHFLPSVYNFVTMINFTVTFQGLQDQLLSTVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILDDDKIVDTLRKSKMTSNEISKRIEATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQINYMYQFSLDWFHQVFVSSVVSKSKEQEHSFKREKVSPKEVHEF-ISISKEPNLENEKNLLDKHIKSAIDMLTKSIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWNIFLYSGILINIKSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLCKSLLSNVSQWDTFKNSKAVYSLISTPFSSENASLEENTKPPEEKHTF---------------------CLLLRAINHTG-------------------TDLGPVGRGQWLTSTACDRHTDVCSFSFALN---------------------DGVPDVEHVQDIFYGHCVDKYHVKVLR---------------------------------------------------------PESLNN---------------------------------SVRKFITEKMGNKYLQRTGVNLKDAYKGSNARTPLILIQTHG---------------------------------------------------------------SASIKDYIHIIQSLPDDDLPEVLGIHPEAIRSCWETQGEKFIENLIAMQPKTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEEIA-VGTPSTLKSMMSSSIWESLSKNLKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQLAIKGEIILTQELEEIFNSFLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWAKVAYTAIQRRYMRFVTVWKQSIPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAVLQDYGRSRGIAVDALTFTHHVISN-TTDKDEKFSVFMPKKLNIVRRAFKG-SASSHTGVYIFGLFIEGARWNREQKILEDSLPLEMCCDFPDIYFLPTKISTKTPN-ASNQTDSELYAFECPVYQTPERSRILATTGLPTNFLTSVYLSTKKPPSHWITMRVALLCEKNEK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : : : : .: . *: . : . . : .. : * .. * : * : : : :: : ::... .:. * . . : :** .. :: :: .* . :: * : : : *. ** . .: * . :: :. * : .*.:..* * ** . .: . : : . : : ::: .:: . : : *: ::: . :.. . ..::. . .** .* : *: *: :: : *:*:***: *::************: ***::*.*** *:*.: ******:::******* :* :*******:** **** ::*: *:**:**********:*:. **:**. ** *** *::**.*:* *..: : * ::* * : * * * *.*: * **:::* * . **:*:**.***:.:*** *: .**.*: : * :::.:. *. : *:* .:. . : *: * : ::* :::::*: :*: ** :**:** ::****: **.*:* ::**::::*** :***:**. *** **.**::****:***. ** :*:*** :.****:* *:. * :*** **: *:::**.*:::**.*::* *:*** * ::* *:**: :* *:*:*:**: **: * *.::::**:* *:::***:.:*:::.:*******::::::**. **:*:*: .::: :***::.*** * .*:***.*** ***:*:**.:.* : * :::*:*..*: *** *.*:** **: :. : :*:::*.:*::::*::***:** ** *** ******** *****.:**.**:: *:.**** :*** **** : **:**.* **: :***:**.**::****.:: *** ********:*.*:* .** ** *:* :: :*:::* **. :*** ***::*.* **: ******: ::*:*:**. :**** ***:**** ******* *.*:**.********:.********:****:* ***::*****.** **************. ..: .* .:* *** :: : : *.**:*:*:*:********:**:** * **:*.*** *** *::*****:**:*: ***:****:.*****:. **:** ****:*:**:**:*:** ****: .* *.** .: *** :*:**:****:***:.* **** **.** *:** :** * ::*:***.* :**:***:*:*..** ******:***.****:*************:****** **::. : : **:* ** : :*****:*******:**.******: *****.******:**.**::**.. :* . *: :.. ::****:*::. * :: *:*** ::** .* ** ::******:****:* :*:****:***:************:******::**.*.* :*:*: ::***:*************:*****::** :.*.*::***:**:.** .*::*:::::** * *::::***:**********:** : :*.: *. * .*:: : ... : ::** :*: *:**:**. :***:*********** *:***:*.*:: * .:* ** *:*.*:** :.:*:* :.*: ** ** .* *:******::****:*******. :****: * *:..:* * ::* .: :.**::***:**::.:*******::*:**:*:*** *********::****:***: * *:************:**:****:* **.*****::** .. .. :********** ******.*. ***:** :*:*****:* .*:***::: *: :*****: * ****::*****::**: .***:**.** *: **********.:*:*.::*** *****.*:: ::** :::*: ***:**:*: ****: :: :. **.**:.***************::***:**:*:**.*:*:**::.*::*: .::*****:********. *******:.** **..*::*:***:* ** *:*******:**:****.*****.***:******::***:***:**.* **********:*****:***********:*:***:*****:****.***::************:*::*********:*************:*****:*******:*.***:***:**********::****:.****** **::*******:***************** *** *********:**:*** *********. ******** **: .*****:* :****:****:** *******.***::* :*******: **::*..**** ** . . :******::**:*:********:************:******:*******:**::****************:***.****: **:***::**:****.*:*********: *:****:*** ****************:**.* :: ******:*:: **** .***:*::: .:* :..* ::..*. :* *.: ***.*: * ::**..*: **:.:***********.****** ***.**:.::...* ****************:.******. :*:.**.* *** .. ****: * *******:*.::*.*****.***** .**::*::: *****:* ** *: . ::..:..:* . : *:* * :.. .* : .: *** . *:.: ** * : :.::::: . :: .*: *:.*:. *: * : .* * *: :..*: ...: :: . ***:** * ****:**** **:******* : * :.:*:***** **** :.. **.* **:*.:***:***:: :******.*::: .*:. ::**.:** * :*::.:*****.**:.***:**:**:*** *******.***:**** *** :*** ::***. *** ****:**:**:*** *:.:****:************:*::*** *:*.*:: .**.:* * .:. :***:****.*** *****:*:******::**::*:*****:** * :::.:* :: *:****:***: . *******::*****: :*::***:** ::**:**** ******: . *:* *:* :****** ****:* ****..****:*.***********:********* ", "identical_positions": 1837, "similar_positions": 984, "identity": "39.57%" }, { "cls_id": "homologset.agr.MGI:2444527", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M1Q7P2-1", "uniprot_id": "A0A8M1Q7P2_DANRE", "id": "A0A8M1Q7P2-1", "name": "", "aln": "-----------MVSGLGRCLAAAALLSFLLFLSSLWLPQGTVQGCEDSWR-----------------------------------PCLSAYKSAKQVDHASIPEELRASDLIRECNGQKFQVSRLLLHLNSALGPASDVLLDPYLLCWEELIKFMEALGPLVGFFTHKVEEKIALIRQLS--LEESTRHSVTASNSMMYGAQHEAP-------PPGHAYHSVHSMLEAELQRGVVSFDQQTPSGSRTLLRLHRSLLWLQLLLEKLGTEREG----RSFGELCREAYLEVLAPHHPWLVQRAAELVFHAMPDRSVFLQLVCVRT-QEEAEPVMRIVVAAIREIHQRTQRELEIRNMLDLP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A2CF29-1", "uniprot_id": "A2CF29_DANRE", "id": "A2CF29-1", "name": "", "aln": "-----------MDV---RCRACVVVIFILLLLGSLCLHR-ILEHHSEVY--------------------------------------------SVKIKVVSLVTDNTSDAPLSVCPDQSFQIAYLLAHLQAAPLAANDVLLKPYLASWDELIKFLEALGPIVGIISQEIESKTTIIRDLAQKAEEEEKKMIERKETTKQLAQSKSSNYSKMDQTLSSGYTSVRSMIKMELENGLVDFQTQTNSGCRTLLRLHRALLWLQNFLHELGKDVAKGERLRRPSDLCKETYQRTLARHHSWWARKAAELAFLAMPERSYFYKLVCVKT-QAEASVVLNRVVKAIEKVYKRNEVALQEHDMLDLP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5Y8A9-1", "uniprot_id": "A0A8I5Y8A9_RAT", "id": "A0A8I5Y8A9-1", "name": "", "aln": "MVLGVSLSP-ALGRWFRHAIPFAIFTLLLLYISVWLFHEWPFELPAQRTQQSGLWELKLSSPSPALTSLLPVTSGVLPGCRPGVQSCNPERALPSQIGPALRPLVVPEKEEP-PCLRPHGLLGRMVSPFLACMSPEGDVELSQYLAGWRELLRLLTPLGSVFAFATSEASNKVTALEAHVHGPDASHYTSLVTMATWERRAV-------------------------LLERPGTTPRHLARPSGSQTLLLLHRALRWSQLCLHRVATGKLGG---PEAGAQCRDAYSTALAPYHPWLIRQAARLAILTLPSRSRLLQLACPGTGEADARVALARAARVLEDVYNRTQGLLASHGLLQLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0R6-1", "uniprot_id": "GLTD2_MOUSE", "id": "Q8K0R6-1", "name": "Glycolipid transfer protein domain-containing protein 2", "aln": "MVMGVSLSP-ALGRWFRHAIPFAILTLLLLYISIWFFYEWPFPLPAQRTQQSGLRGLKLPSPSPVLGSLLSFP--------AGVQSCNPERPLPSQTGPAARPLVVPEKEEL-PCLGPHGALGRMVSPFLACMSPEGDVALSQYLAGWRELLRFLTPLGTVFAFATSEAFNKVTDLEARVHGPNASHYTSLMTMITWERGAG-------------------------LLQRPGTEPGHSAGSSGSRTLLLLHRALRWSQLCLHRVATGTLGG---PDAGTQCGEAYSTALAPHHPWLIRQAARLAILALPSRGRLLQLACPGTGEADARVALARAAGVLEDVYNRTQGLLAGHGLLQLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NH11-1", "uniprot_id": "GLTD2_HUMAN", "id": "A6NH11-1", "name": "Glycolipid transfer protein domain-containing protein 2", "aln": "--MGVAARPPALRHWFSHSIPLAIFALLLLYLSVR-------SLGAR----SGCG--------------------------PRAQPCVPGETAPFQVRQESGTLEAPERKQP-PCLGPRGMLGRMMRRFHASLKPEGDVGLSPYLAGWRALVEFLTPLGSVFAFATREAFTKVTDLEARVHGPDAEHYWSLVAMAAWERRAG-------------------------LLEQPGAAPRDPTRSSGSRTLLLLHRALRWSQLCLHRVATGALGG---PDAGVQCSDAYRAALGPHHPWLVRQTARLAFLAFPGRRRLLELACPGATEAEARAALVRAAGTLEDVYNRTQSLLAERGLLQLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MLW4-1", "uniprot_id": "Q8MLW4_DROME", "id": "Q8MLW4-1", "name": "Glycolipid transfer protein domain-containing protein", "aln": "------------------------------------------------------------------------------------------------MSKTSLATQTNGTAEN----GNCFDILKVSNLFETSLLDEDDVQLDAYLAAYEEIMKFFQLMGSVFSFVSSDVRSKIDILYALRAKDAEEQEHFNTFRTMLD------------------------------YEKEAQLLTQKGYVSGSRTLLRLHRGLDFVYEFLNRIQAIPDDQ----KTVDVCKEAYDDTLGKHHSFLIRKGARLAMYAMPTRGDLLKKVCSDVEAAKEN--LPSMLKHMRTNYDRTEDLYTLYDLHSLP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :. .** *. ** : ::.:: :*.:..: : . * : . . . . **.:*** ***.* : *..: * ::* .*. :*.: :: *.*.: ::* * : : .* . . : :. :.*.: .: .*.", "identical_positions": 28, "similar_positions": 63, "identity": "7.8%" }, { "cls_id": "homologset.agr.MGI:2444529", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K2D6-1", "uniprot_id": "DCTD_MOUSE", "id": "Q8K2D6-1", "name": "Deoxycytidylate deaminase", "aln": "-----------------------------------------------------------------------------------------------MSDISCK-------------KRDDYL----------------------------------------EWPEYFMAVAFLSAQRSKDPSSQVGACIVNTENKIVGIGYNGMPN---GCSDDLLPWRRTAEN-----KLDTKYPYVCHAELNAIMNKNSADVKG-CSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSEETTAARLLFKLAGVTFRKFTPKYSKIVIDFDSINSR-PSQKPQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M9G0-1", "uniprot_id": "DCTD_RAT", "id": "Q5M9G0-1", "name": "Deoxycytidylate deaminase", "aln": "-----------------------------------------------------------------------------------------------MSDISCK-------------KRDDYL----------------------------------------EWPEYFMAVAFLSAQRSKDPSSQVGACIVNTENKIVGIGYNGMPN---GCSDDLLPWRRTAEN-----KLDTKYPYVCHAELNAIMNKNSADVKG-CSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSEETTAARLLFKLAGVTFRKFTPKYSKIVIDFDSINSR-PSQKPQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32321-1", "uniprot_id": "DCTD_HUMAN", "id": "P32321-1", "name": "Deoxycytidylate deaminase", "aln": "-----------------------------------------------------------------------------------------------MSEVSCK-------------KRDDYL----------------------------------------EWPEYFMAVAFLSAQRSKDPNSQVGACIVNSENKIVGIGYNGMPN---GCSDDVLPWRRTAEN-----KLDTKYPYVCHAELNAIMNKNSTDVKG-CSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSDEATAARLLFNMAGVTFRKFIPKCSKIVIDFDSINSR-PSQKLQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWA2-1", "uniprot_id": "DCTD_DROME", "id": "Q9VWA2-1", "name": "Probable deoxycytidylate deaminase", "aln": "-----------------------------------------------------------------------------------------------MAEVSAQDLISQLSKSPESHKRKEYL----------------------------------------HWDDYFMATSLLSAKRSKDPVTQVGACIVDSQNRIVAIGYNGFPR---NCSDDVFPWSKAKKGSQEFDPLEDKKMYVVHAEANAILNSNGMSLSG-TRLYTTLFPCNECAKLIIQVGISQVLYLSDKYADKPTYRASKRMLDAVGVEYKRHIPQKKTITIDFDTFPEEDPNASLGLNELHL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P06773-1", "uniprot_id": "DCTD_YEAST", "id": "P06773-1", "name": "Deoxycytidylate deaminase", "aln": "MLIGVSGTKFCGCEDVINMLVDHFHFELLNHLDNPEEILDYATKNYTKNSVIFLEKLSLLEKLEKRPFFVHLSIDAPVTTRVALYRKTTQAESLSLEQIIQAIDQHDFQPEGIKLREKSHLRFKIVNEDRRGRRQSLINNITTQLKILDDKEKQMAPLMRPSWDSYFMKLATLAASRSNCMKRRVG-CVIVRECRVIATGYNGTPRHLTNCFNGGCPRCNDGDS------RNLHTCLCLHAEENALLEAGRDRVGQNATLYCDTCPCLTCSVKIVQTGISEVVYSQSYRMDEE----SFKVLKNAGITVRQFSFTEEPRIVMI-------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :...:* * .*** : *:*.**: :** *:: : :::. **** *. .* :. * . .. : : *** **::: . : :* ** *: *:*.**.:*:: .. *. : ::. .*: ::. . : : ", "identical_positions": 35, "similar_positions": 58, "identity": "10.23%" }, { "cls_id": "homologset.agr.MGI:2444530", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BLV3-1", "uniprot_id": "SL9A7_MOUSE", "id": "Q8BLV3-1", "name": "Sodium/hydrogen exchanger 7", "aln": "MEPSDAARPGPGRAFRGLSPRLLLLPLLPVLLGRGLRAGAAASS---GAAAEDSSAMEELATEKEAEES----HRQDSVSLLTFILLLTLTILTIWLFKHRRVRFLHETGLAMIYGLIVGVILRYG-TPATSGHDKS----LSCTQEDRAFSTLLVNVSGKFFEYTLKGE-------ISPGKINNVEQNDMLRKVTFDPEVFFNILLPPIIFHAGYSLKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMKIVGQLSDKFYYTDCLFFGAIISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAIVLSSSIVAYQPAGLNTHAFDAAAFFKSVGIFLGIFSGSFTMGAVTGVVTALVTKFTKLHCFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGITQAHYTYNNLSVESRSRSKQLFEVLHFLAENFIFSYMGLALFTFQKHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGRRHK------------------IGWNFQHMMMFSGLRGAMAFALAIRDTASYARQMMFTTTLLIVFFTVWVIGGGTTPMLSWLNIRVGVEELSEEDQNENRWQYFRVGVDPDQDPPPNNDSFQVLQGDGMD----------------------------SVGGSRTKQESAWIFRLWYIFDHNYLKPILTHSGPPLTTTLPAWCGLLARCLTSPQVYDNQEPLREDDSDFILTEGDLTLTYGDSTVTANGSSSS----YTASTSLECGRRTKSSSEEVLERDLGMGDQKVSSRGTPLVFPLQENA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LXD6-1", "uniprot_id": "A0ABK0LXD6_RAT", "id": "A0ABK0LXD6-1", "name": "Sodium/hydrogen exchanger", "aln": "MEPSDAARPGPGRAVPGLSPRLLLLPLLPMLLGRGLRAGAAASSS--GAAAEDSSAMEELATEKEAEES----HRQDSVSLLTFILLLTLTILTIWLFKHRRVRFLHETGLAMIYGLIVGVILRYG-TPATSGRDKS----LSCTQEDRAFSTLLVNVSGKFFEYTLKGE-------ISPGKINNVEQNDMLRKVTFDPEVFFNILLPPIIFHAGYSLKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMKIVGQLSDKFYYTDCLFFGAIISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAIVLSSSIVAYQPAGLNTHAFDAAAFFKSVGIFLGIFSGSFTMGAVTGVVTADVTKFTKLHCFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGITQAHYTYNNLSVESRSRSKQLFEVLHFLAENFIFSYMGLALFTFQKHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGRRHK------------------IGWNFQHMMMFSGLRGAMAFALAIRDTASYSRQMMFTTTLLIVFFTVWVIGGGTTPMLSWLNIRVGVEELSEEDQNEHRWQYFRVGVDPDQDPPPNNDSFQVLQGDGLD----------------------------SVGGSRTKQESAWIFRLWYSFDHNYLKPILTHSGPPLTTTLPAWCGLMARCLTSPQVYDNQEPLREDDSDFILTEGDLTLTYGDSTVTANGSSSS----YTASTSLECGRRTKSSSEEVLERDLGMGDQKVSSRGTPLVFPLQENA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96T83-1", "uniprot_id": "SL9A7_HUMAN", "id": "Q96T83-1", "name": "Sodium/hydrogen exchanger 7", "aln": "MEPGDAARPGSGRATGAPPPRLLLLPLL---LGWGLRVAAAASASSSGAAAEDSSAMEELATEKEAEES----HRQDSVSLLTFILLLTLTILTIWLFKHRRVRFLHETGLAMIYGLIVGVILRYG-TPATSGRDKS----LSCTQEDRAFSTLLVNVSGKFFEYTLKGE-------ISPGKINSVEQNDMLRKVTFDPEVFFNILLPPIIFHAGYSLKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMKIMGQLSDKFYYTDCLFFGAIISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAIVLSSSIVAYQPAGLNTHAFDAAAFFKSVGIFLGIFSGSFTMGAVTGVN-ANVTKFTKLHCFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGITQAHYTYNNLSVESRSRTKQLFEVLHFLAENFIFSYMGLALFTFQKHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGRRHK------------------IGWNFQHMMMFSGLRGAMAFALAIRDTASYARQMMFTTTLLIVFFTVWIIGGGTTPMLSWLNIRVGVEEPSEEDQNEHHWQYFRVGVDPDQDPPPNNDSFQVLQGDGPD----------------------------SARGNRTKQESAWIFRLWYSFDHNYLKPILTHSGPPLTTTLPAWCGLLARCLTSPQVYDNQEPLREEDSDFILTEGDLTLTYGDSTVTANGSSSS----HTASTSLEGSRRTKSSSEEVLERDLGMGDQKVSSRGTRLVFPLEDNA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDB4-1", "uniprot_id": "A0A8M2BDB4_DANRE", "id": "A0A8M2BDB4-1", "name": "Sodium/hydrogen exchanger", "aln": "MEAAKAPKP----WTLYLPNPSSLFPLFVFILSQCYRISA------------DDGGIEELATEKEAEES----HRQDSVNLLTFILLLTLTILTIWLFKHRRVRFLHETGLAMIYGLLVGVILRYG-IPSTSYHNKTP---PSCMLKEGPVSTVLLNVSGKFFEYTLKGE-------INLREIHSVEQNDMLRKLTFDPEVFFNILLPPIIFHAGYSLKKRHFFRNLGSIITYAFLGTAISCFVIGNLMYGVVKLMQVLGQLTDKFYYTDCLFFGAIISATDPVTVLAIFNELHADGDLYALLFGESVMNDAVSIVLSSSIVAYQPSGANTHTFDASAFFKSVGVFIGIFSGSFAMGAVTGVVTALVTKFTKLHCFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGITQAHYTYNNLSEESTKRTKQLFEVLHFLAENFIFSYMGLALFTFQNHVFSPIFIVGAFLAIFIGRALNIYPLSFLINLGRRHK------------------IRGNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFTTTLLIVFFTVWVFGGGTTPMLSWLHIRVGVD--------------------PDQDLQPCGDSFQVLQGDGSQ----------------------------SEGQSKTKQESAWLFRLWYTFDHNYLKPILTHSGPPLTSTLPACCGPLARCLTSPQAYETHEPLRDNDSDLILNEGDLTLTYGDTAITANGASSSSGPEGSAGIWGLNGKRSDSTSEDALERELDTREHELLSRGTRLVFPIEDHA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPJ4-1", "uniprot_id": "Q8IPJ4_DROME", "id": "Q8IPJ4-1", "name": "Sodium/hydrogen exchanger", "aln": "--------------------MLLIVGFALCVLAPGC-----------------SATDTDIALDAKATLN----HRIQSLDLLVFVFLLALTVLTIWLFKHHRVSWLHETGLAVIYGLIVGAIIRYAGTSATLVHMQVEPQGVPTYSDKLPPDTLWFRYPVNQTNGTKPPEGIKTYAYVFRGQVHDVDENEIDLKATFDPEVFFNIILPPIIFYAGYSLKKKYFFRNLGAILTFAIVGTTLSAFLIGGFMYGCVKLMPKY--LSSSFTFLDSLYFGALISPTDPLTILAIFNDLRVDVNLYALVLGESVLNDAVAIVLSGAIQNYGEHYSNTGEFETTAFLRSLSDFFSIFLLSLMIGAAMGCLTALMTKFTRVRDFPLLESALFVLMSYSTFLLAEATELTGVVAVLFCGICQAHYTYNNLSEDSRQRTKQIFELLNFLAENFIFSYIGVSMFTFPKHHFDAGFIITAFICAAIGRAVNVYPLSWLLNIKRKPK------------------ISTNFQHMLFFAGLRGAMSFALAIRNTVSDERQTMLTATSLIVIFTVVIQGGAANFLLNWLKIPVGVDDETEQLNNYQVHSVYN--SMDNSHPQTSDGYLQDVEGGGVNRNKMRLSGGTDTNLDTPVDGTNGSLGGASGGRRRNSHEKAILARIWGNFDTKYMKPLLTHSRPTLLETLPVCCNPIARLLTT------TQQLTQDGSEFRRVDSDSDICIDN--DTGNGLSQD-----GSGAAPGVGRR-NSLSRSVHLNEANHLANELSLVANNFM-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04121-1", "uniprot_id": "NHX1_YEAST", "id": "Q04121-1", "name": "Endosomal/prevacuolar sodium/hydrogen exchanger", "aln": "-----------------MLSKVLLNIAFKVLLTTAKRAVDPDDDDELLPSPDLPGSDDPIAGDPDVDLNPVTEEMFSSWALFIMLLLLISALWSSYYLTQKRIRAVHETVLSIFYGMVIGLIIRMS------------------------------------------------------------PGHYIQDTVTFNSSYFFNVLLPPIILNSGYELNQVNFFNNMLSILIFAIPGTFISAVVIGIILY----IWTFLGLESIDISFADAMSVGATLSATDPVTILSIFNAYKVDPKLYTIIFGESLLNDAISIVMFETCQKFHG-----QPATFSSVFEGAGLFLMTFSVSLLIGVLIGILVALLLKHTHIRRYPQIESCLILLIAYESYFFSNGCHMSGIVSLLFCGITLKHYAYYNMSRRSQITIKYIFQLLARLSENFIFIYLGLELFTEVELVYKPLLIIVAAISICVARWCAVFPLSQFVNWIYRVKTIRSMSGITGENISVPDEIPYNYQMMTFWAGLRGAVGVALALGIQGEY-KFTLLATVLVVVVLTVIIFGGTTAGMLEVLNIKTGCISEED--------------TSDDEFDIEAPRAINLLNGSSIQT---------------------------DLGPYSDNNSPDISIDQFAVSSNKNLPNNISTTGG---NTFGGLNETENTSPNPARSSMDKRNLRDKLGTIFNSDSQWFQNFDEQVLKPVFLDNVS----------------PSLQDSATQSPADFSSQNH---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . :* : .. . . .* *: :::** :: : : :.::*: :*** *:::**:::* *:* . : : . **:.. ***::*****: :**.*:: **.*: :*: :*: ** :*..:** ::* : : .: : *.: .** :*.***:*:*:*** :.* .**::::***::***::**: : : ::.:.. . *: * *: :*. * * : *.*::: :* :*:.*:.*:::.::::::. ::*:*::***** **:* *:* * * :*::* *:***** *:*: :** : :.. :*: * :. :.* ::*** ::* : * * *:* * :::*****:..***: : ::::. ::*.:** : ** : :*. *:* .* :. :: ::*.. : . .:. : . : : :: : *: .. . * :. . : :.: .: . .. * . .. . :: ", "identical_positions": 134, "similar_positions": 211, "identity": "16.86%" }, { "cls_id": "homologset.agr.MGI:2444531", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P86410-1", "uniprot_id": "RLGPB_RAT", "id": "P86410-1", "name": "Ral GTPase-activating protein subunit beta", "aln": "MYSEWRSLHLVIQNDQG---HTSVLHSYPESVGREVANAVVRPLGQALGHSPVSASQSLLYTDKDVKWTMEVICYGLTLPLDG-ETVKYCVDVYTDWIMALVL-PKDSIPLPVIKEPNLYIQSILKHLQNLFVPRQ-------------EQGS-SQIRLCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAVISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRP-------------------------------RSDSAP-----------------------------------------------------------------------PTPVNRLSMP----------------------------------QSAAVNTTPPHNRRHR-------AVTVNKATMKTSTVTTAHTSKVQHQASSTSPLSSPNQTS-------SEPRPLP------------------------------APRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTASFIQILLSYKSSIATQASMEFRRKGSQMSTDTMVSNP-VFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLS-----------------------SVILNSPPLFCCDLKGIDVVVPYFISALETILPDR--ELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEALG--------CQMEMG---GGENNLKSHS--RTNSGISS--------------ASGGSTEPTTPDSERPAQALLRDYGS-T----------DSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKV-MVDLGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKN-SEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSR--LPTINKHS------FRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQK-LFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEMHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALK--EPANSRLPP---HLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNV--ESSRNVQPHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINSCDDGEGSEQDEVTSSEDVGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILK-QPPLTLELVPNHTDSLNSSQRLSPSSRMKKLPQGR-------PVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQZ4-1", "uniprot_id": "RLGPB_MOUSE", "id": "Q8BQZ4-1", "name": "Ral GTPase-activating protein subunit beta", "aln": "MYSEWRSLHLVIQSDQG---HTSVLHSYPESVGREVANAVVRPLGQALGTSSVAGSESLLKTDKEVKWTMEVICYGLTLPLDG-ETVKYCVDVYTDWIMALVL-PKDSIPLPIIKEPNLYVQSILKHLQNLFVPRQ-------------EQGS-SQIRLCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAVISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRP-------------------------------RSDSAP-----------------------------------------------------------------------PTPVNRLSMP----------------------------------QSAAVNTTPPHNRRHR-------AVTVNKATMKTSTVTTAHTSKVQHQASSTSPLSSPNQTS-------SEPRPLP------------------------------APRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDNSMTASFIQILLSYKSSIATQASMEFRRKGSQMSTDTMVSNP-VFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLS-----------------------SVILNSPPLFCCDLKGIDVVVPYFISALETILPDR--ELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIG--------CQMEMG---GGENNLKSHS--RTNSGISS--------------ASGGSTEPTTPDSERPAQALLRDYGS-T----------DSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKV-MVDSGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKN-SEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSR--LPTINKHS------FRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQK-LFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEMHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALK--EPANSRLPP---HLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNV--ESSRNVQPHFLEFLLSLGWSVDVGKHPGWTGHVSTSWSINSCDDGEGSEPDEITSSEDVGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILK-QPPLTLELVPNHTDSLNSSQRLSPSSRMKKLPQGR-------PVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86X10-1", "uniprot_id": "RLGPB_HUMAN", "id": "Q86X10-1", "name": "Ral GTPase-activating protein subunit beta", "aln": "MYSEWRSLHLVIQNDQG---HTSVLHSYPESVGREVANAVVRPLGQVLGTPSVAGSENLLKTDKEVKWTMEVICYGLTLPLDG-ETVKYCVDVYTDWIMALVL-PKDSIPLPVIKEPNQYVQTILKHLQNLFVPRQ-------------EQGS-SQIRLCLQVLRAIQKLARESSLMARETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPAFKVPDEDASLIPPEMDNECVAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMPQELNQYPCLKHLPQIFFRAMRGISCLVDAFLGISRP-------------------------------RSDSAP-----------------------------------------------------------------------PTPVNRLSMP----------------------------------QSAAVSTTPPHNRRHR-------AVTVNKATMKTSTVSTAHASKVQHQTSSTSPLSSPNQTS-------SEPRPLP------------------------------APRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTA------------ITTQASMEFRRKGSQMSTDTMVSNP-MFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQINDY-VCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDR--ELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVKSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIG--------CQMEMG---GGENNLKSHS--RTNSGISS--------------ASGGSTEPTTPDSERPAQALLRDYALNT----------DSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKV-MVDSGDRKRAISSVCTYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKN-NEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSR--LPTINKHS------FRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQK-LFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEIHLEQQSEEELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALK--EPANSRLPP---HLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNV--ESSRTVQPHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINCCDDGEGSQQ-EVISSEDIGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILK-QPSLTLELFPNHTDNLNSSQRLSPSSRMRKLPQGR-------PVPPLGPETRVSVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQEVGLKNCSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATR5-1", "uniprot_id": "A0A8M3ATR5_DANRE", "id": "A0A8M3ATR5-1", "name": "Ral GTPase-activating protein subunit beta", "aln": "MYSEWRSLHLVVQSDQG---HLSVLHTYPAGVGRDVANAVVRPLGNSLGG---VPSECLLKTDKEVKWTMEVLCYGLTLPLDG-DTVKLCVDVYTDWIMALVS-PRDSIPQPIIKEPDLYVQTILKHLHNLFLPRP-------------ENFSLVHFKLCQQVLSAVQKLARDSSSMARETWEVLLLFLLRINDTLLAPPTVGGGLAEKLAEKLISVLFEVWFLACTRCFPTPPYWKTAREMLANWRHHPPVVEQWSKVIAALTSRLLRFMYGPSFPPFKVPEEDASLIPAEMDNDCVAQTWYRFLHMLSNPVDLSNPVIVSSTPKFQEQLLGVNSVPHEVIQHPCLKQLPQIFFRAMRGISCLVDAFLGISRP-------------------------------RSDSAP-----------------------------------------------------------------------PTPVNRLSMPP---------------------------------PPTTTNTTPPHNRRHR-------PTAVAKTTSKSSTTG---QTRVSHQPSSTSPLSSPNQTS-------SEPRPLP------------------------------APTRPKVNSVLNLFGQWLFDAALVHCKLHSGLSRDSSMTA------------LATQAGVELRRKGSQMSTDTMVSNP-MFDANEFPDNYESGRAEACGTLCRIFCSKKTGEEILPVYLSRFYMVLIQGLQISDF-ICRPVLASIILNSSALFCSDLKGINVVVPYFISALETILPDR--ELSKFKSYVNPTELRRASIHILLSMLPLPHHFGNVKSEVLLEGKFSNDDNSLHDKAVTFLSLKLRLVNILIGALQTETDPINTQMILAAMLNIVQDSALLESVG--------AQAEVGSVDGSHSLAKSHS--RNNSGISN--------------ASAGSSEATTPDSERPAQALLRDYDT--------------AAGLLIRSIHLLTQRLNSQWRLDMSISLAALELLAGLAKVKV-SVESSDRKRAVSSVCSYIVYQCSRPAPLHSRDLHSMIVAAFHCLCVWLTEHPDMLNEKDCLIEVLEIVELGISGSKSKT-GEQEVKYKGDKEHNPASMRVKDAAEATLSCIMQVLGAFPSPSGPASPCSLLNEDTLIKYSR--LTSTSHSN------FRYFVLDNSVILAMLEQPLGNEQN-PCPSVTMLIRGMSGRHAWTMQLFHQPRGARANQKQVFVPESRPTPKNDVGIRFNVKHRPFPEEVDKIPFVKADLSIPDLHDIVDKELEQQHDKLRVVMGKQIDYETKLEHHTEDLWRNKAFPDPLTDCKPPAPAQEFQTARLFLSHFGFLSLEALK--EPGNSRLPP---HLIALDSSVPGFFDDVGYLDLLPSRPCDTVFIFYMRAGQKSSQEILKNV--ESSANVQPHFLELLLSLGWPVEVAQHPGWTGSVFTSWTINTSN-GADTPDDSVTLG-DTGGGVFNGEKQVLYYADALTEIAFVVPSLSDSSAESSEHSFPTADSDSQMELLPSLLK-QPNLTLELFPNHSDNMGPAQR-SPTAKNKKLPPGR-------TIPPLGPDTKVLVVWVERYDDIENFPVSELLAETSTGVETAVNSSAS-RSSSSEKDVPIVFIHPLKTGLFRIKLQGALGKFNMVIPLVDNMVVSRRSLGFLVRQTVINACRRKRLESDSYSPPHVRRKQKIAEIVNRYRNKQLEPEFYTSLFLEVNETSLKP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JEC6-1", "uniprot_id": "X2JEC6_DROME", "id": "X2JEC6-1", "name": "Rap-GAP domain-containing protein", "aln": "MYSEWASLSAQITANSCGAQCFSVLNKFPASAGREVVVSVVKQLGTNLGITQNAEPSHLVK-DEEVKWCMDVICFGLSLPLQEHETIKDCVNVYCEWLTALHPQPRISVPKPICEDANLYARQIINHFHNLFVPRQGEILPFLYQTTLGADTIKRQAVLCHRVLRTLQQTAQISQLMDRQTWDTLLLFLLAINEILLAPPTVKDDVGDQLCERVLSVLFEVWLLACVRSFPSPSMWKTLQESCAMWRHRVALVDQWNRVNLALTARLLEFSYGPAFPQLKNADEDGQLIPIGMSNDCVAQTWYRFLRMIGNPTALCSPHIISKSSHFVQWALTHEKG-AETHQHPCLQQLPQIFLNAMKGISSQVDAFLGVYQPPPQQTDGVVTNLLEIRHSLNEATSSTLQQFIHSSSATNIANQQNQPAHHHHHLHYPHLHLHGAGSFLRDNFMSNSASSALNAIMGHHGGHHGHHHQQQQQQQQQLQISASPTSSLTTSGSSAVGSTSAGGSHSAGVVGSISFGATESPGPGQASASATPTPPLQRRLAKSFSVAPTITQQKGLSKTSLIGLTGGGARNAISSSSTTTTNAGSTGGTGSGDGSAPAPLPTTPTSTSGPPSASSSINSLPLTSMGAGVELAVARPKCNSILHVFHEWLFEAAHIGGDTWRQNRKKQACEAS----------KRPSSMIMEHRKGSISLSQPNSLNDPQSLPPTLTIDKYESGRAEAIGTLCKIFCAKKTGEEILPVYLARFYMALQQCLKITESRECDETLASILLHSSDLFRLDLDGINVLLPGFIAALEIVLPDKDLKLKTQSMVFNRTELRRSAINILLSIMVLPLHYQTLP--------IRDLTCESSEKMFTFIQLKSRLMNILMNALQVETDAQNTHMLLGGLLLCVQDAVTFEETELGGGNANLSQNSSGVQHHDANLLSSACSERSASLVSAGTASLGGQTTATMGAGSGSIRDTASAHDYPSLTISDDMSFEFGQELEGVTTYDNAHALFVRATYLVCHRLISSWKTDLNVSLAALELLSGLARLHIRETDALECKRAVKWICDYICYQCSRPPPAHSKDLHSTIVAAFQCTAAWLMQHPYLLQDKDCLQTVLEVVELGISGTKSQSKGTDIPKFKDEKELKPASMRVRDAAENLLTIILEQVGYFPSECGPESISSLLDELALMKHCNSMVPAAAASSEQAIAKFKYFVTENSTILALLEEPLGNDQD-PQPTVTLLIRGPFGRHAWTMQLRHLPR-SKSGIKYHAINPGRPIPMNDVTQRLDSEQKNFPDGVDKVQPCVADYSIPTIEQMREQYGTAVIRELESLLENQSIHEKLAWAEADTSADSLSH---AQECVPPTVCHEFHAARLFLSHFGFLGFETRNPQNPAEALGNPPQRPLIVLDTKSAAFAADLDRLDKLSARTHDSVYVFYVKSGQTSAQQIIANMGEESSASHDPHFASMLQTLGWPVQVSEHSGWTGFAHNSWSL------KGTPEEQLKSTANELN--YNGSQRVLYWADVSSEIAFVVPTTWNLRYNSDTCDSGSISSTDQIGSSNVWTRGEADSAAGLAKSKSRNLSLELDTNRRDVKEPVPPTRRKGNVTKPTLLAQAPAKIFLVWLESYEDYLNFPLEDLLAYTRTGEELQT------QQLPRASDCHVIFVHSLLSGLLRVKLQGPPGRMSFATPLVDGMVLSRRVVGNLVRQTALNISRRRRLDNDNYQPPHVRRRLKVQDIVQKYKMDLSEADLLAHLFQRAI------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ** : :. ***:.:* ..**:*. :**: ** ** .. *: *::*** *:*:*:**:***: :*:* **:** :*: ** *: *:* *: ::.: * : *::*::***:** : : ** :** ::*: *: *. * *:**:.****** **: ******* ..:.::*.*:::.******:***.*.**:*. *** :* * ***: .:*:**.:* ***:***.* ***:** :* .:**..*** *.*:*:****:***:*:.**. *..* ::*.:.:* : * . * *:***::*****:.**:***. ******: :* :*.**. .:*.. *: . .::...*** :** . : * *:* . .**::. :....*. * * *** * *** **:*::* .***:** : . :..: * .:. :* *: . .:* . :.:* : .. *:**:***** ****:***:*********.**: *::*:*. ** **.**:*::* **:*** :***: :*.. . .* *****::*:****:: ** *: .: : : . :* .**:.** **:***:.***.***. **:*:*..:* ***:. :* .* . * . . .* . *. * :* *..** . *:. : *: :: * * .*::*: :*: :** *.*: *:.:********:***:::: .: : ***:. :* ** ******.* **:**** *****:* ..** :** :*::**** ***:*******:**:. . : *:*.:** :******:**** *: *:: :* *** .** * .**::* :*:*:.. :.: . *:*** :**.***:**:****:*: *:**:*:** ** **: ** ** :::. * : ** * *** : . ::: **: ***: ** *** :.:: : :*. : :* :* .:: . :. :* **. .:**::***********.:*: : :*.:: * **.**:. ..* *:. ** *..*. *:*::**::.**.: *:*: *: *** . :*** .:* :***.*:*..*.**** . .**:: .: .: : :**.::***:**. :*******: : :* . .* .:: : :. : * .:: .:. . . :* * . . ::: :**:* *:* ***:.:*:: ** * . :. . .: ::*:*.* :**:*:*:**. *::.:. ****.*::*** :* *****.:* .**:**:.*.*.******: *: :**::*: . *.:: : ** .. ", "identical_positions": 577, "similar_positions": 472, "identity": "32.54%" }, { "cls_id": "homologset.agr.MGI:2444541", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZED6-1", "uniprot_id": "D3ZED6_RAT", "id": "D3ZED6-1", "name": "ubiquitinyl hydrolase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MDPGVGDALGEGPPAPRPRRRRSLR-----RLLNRFLLALVSRSRSGDSPPRAPA-------QPSPYDGDGEGGFACAPGPAPASS------GSPGPDRPLGSQP--QISSGDGARPPGAQG-LKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAVPG----------------RAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSTHGQGSEQLPP-------EASKISEDLRSSAAPPSLGPSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRVGLAVPILSTVAALRKMVAEEGGVPAEEVILVELYPNGFQRSFFDEEDLNTIAEGDNVYAFQVPPLPGPG---TLAAHPPGLSVSPRL-AVRDSQRFSVP--LHSE--------NRVLILFCNLVGSGQQASRFGPPFLIREDRTISWAQLQQCILSKVRCLMRNEV--SAQDLGTLFSIRVVGLSLACSYLSPQDSRPLCHWAVDRALHLRR-PGGPPHVKLAVEWDSSVTERLFG--SLQEERVQDADSVWRQQQAH-QQPSCTLDECFQSYTKEEQLAQDDAWKCPHCQVLQQGVVKLSLWTLPDILIIHLKRFCQVGER---RNKLSTLVKFPLSGLNMAPHVARRSTNSKAGPGPWSS--------------------WKQPICLPTTYPLDFLYDLYAVCNHHGS-LQGGHYTAYCRNSLDGQWYSYDDSTVEPLRED----EVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLMRLGSLNNSTRGSLMSWSSAPCPS-VARVPDSPVFTNGVCQQ---DKG-VEAGPLVQGVGGRSISMKVPPTSRSRHGPFKTMPLRWSFGHRE--KRPGAS-----VELVEYLESRRRPRSTSQSIVPLLTRAAGGDETSASPRSDATLPAKSDNSG--RATGQGTNGVPLSSCHLNHHSALGSLDDGLHTARTRTGNASQDIRLPKKFDLPLTVMPSAEDGKHARPEGQKMTTWKGSSQVGSQSSPPSPSTGLLRNFKDNGLGTLPKMKAKAAMEERAPDKDRGQGTFTLLKSVFWKKEHKRAVRTESS--PPAPSISLASDRLS-PALNEHARGSSPALRIRESPARGLGNHSERDIRSAPSS--------LHLPRKASRPPRASAAVSSQRTIPGELTSYGTLQRVKYHTLSLGRKKSLPESSF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUM9-1", "uniprot_id": "UBP43_MOUSE", "id": "Q8BUM9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 43", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MDPGVGNALGEGPPAPRPRRRRSLR-----RLLNRFLLALGSRSRSGDSPPRPPA-------QPSPYDGDGEGGFACAPGPAPASA------GSPGPDRPPGSQP--QISSGDGARPPGAQG-LKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPG----------------RAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSAHGLVSEQLPP-------EVSKISEDLRPSAAPTSLGPSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRVGLAVPILSTVAALRKMVAEEGGVPAEEVILVELYPNGFQRSFFDEEDLNTIAEGDNVYAFQVPPSPGLG---TLSAHPSGLSVSPRL-PVRDSQRFSGP--LHSE--------NRVVFLFCNLVGSGQQASRFGPPFLIREDRTISWAQLQQCILSKVRCLMRSEV--SAQDLGTLFSIRVVGLSLACSYLSPKDNRPLCHWAVDRALHLRR-PGGPPHVKLAVEWDSSVTERLFG--SLQEERVQDADSVWRQQQAH-QQPSCTLDECFQSYTKEEQLAQDDAWKCPHCQVLQQGVVKLSLWTLPDILIIHLKRFCQVGER---RNKLSTLVKFPLSGLNMAPHVARRSTNSKAGPGPWSS--------------------WKQPICLPTTYPLDFLYDLYAVCNHHGS-LQGGHYTAYCRNSLDGQWYSYDDSTVEALRED----EVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLMRLGSLNNSTRGSLLSWSSAPCPS-MARVPDSPVFTNGVCHQ---DKGGVETRPLVRGVGGRSISMKASPASRSRHGPFKTMPLRWSFGHRE--KRPGAS-----VELVEYLESRRRPRSTSQSIVPLLTRAAGGEETSASPRSDGTLPAKSEDSG--RAIGQGTTGVPLSSCHLNHHPALGSLDDSLHTARTRTGNVSQDIRLPKKFDLPLTVMPSVGDEKPARPEGQKMTPWKGSSQVGSQSSPPSPSTGLLRNFKDSGPGTLPKMKSKAAMEERAPDKDRGQGTFTLLKSVFWKKEHKRTVRTESS--PPAPPISLGSDRLS-PAAMN-----EQALRIRESPAKGLGNHMERDIRSAPSS--------LHLPRKASRPPRASTAGTSQRTIPGEQISYGTLQRVKYHTLSLGRKKSLPESSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q70EL4-1", "uniprot_id": "UBP43_HUMAN", "id": "Q70EL4-1", "name": "Ubiquitin carboxyl-terminal hydrolase 43", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MDLGPGDAAGGGPLAPRPRRRRSLR-----RLFSRFLLALGSRSRPGDSPPRP---------QPGHCDGDGEGGFACAPGPVPAAP------GSPGEERPPGPQPQLQLPAGDGARPPGAQG-LKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPG----------------RAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSSRGPVSEKLPP-------EATKTSENCLSPSAQLPLGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRVGLAVPILSTVAALRKMVAEEGGVPADEVILVELYPSGFQRSFFDEEDLNTIAEGDNVYAFQVPPSPSQG---TLSAHPLGLSASPRL-AAREGQRFSLS--LHSE--------SKVLILFCNLVGSGQQASRFGPPFLIREDRAVSWAQLQQSILSKVRHLMKSEA--PVQNLGSLFSIRVVGLSVACSYLSPKDSRPLCHWAVDRVLHLRR-PGGPPHVKLAVEWDSSVKERLFG--SLQEERAQDADSVWQQQQAH-QQHSCTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLPDILIIHLKRFCQVGER---RNKLSTLVKFPLSGLNMAPHVAQRSTSPEAGLGPWPS--------------------WKQPDCLPTSYPLDFLYDLYAVCNHHGN-LQGGHYTAYCRNSLDGQWYSYDDSTVEPLRED----EVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLLRLGSHAGSTRGSLLSWSSAPCPS-LPQVPDSPIFTNSLCNQ---EKGGLEPRRLVRGVKGRSISMKAPTTSRAKQGPFKTMPLRWSFGSKE--KPPGAS-----VELVEYLESRRRPRSTSQSIVSLLTGTAGEDEKSASPRSNVALPANSEDGG--RAIERGPAGVPCPSAQPNHCLAPG-NSDGPNTARKLKENAGQDIKLPRKFDLPLTVMPSVEHEKPARPEGQKAMNWKESFQMGSKSSPPSPYMGFSGNSKDSRRGTS---------ELDRP----LQGTLTLLRSVFRKKENRRNERAEVS--PQVPPVSLVSGGLS-PAMDGQAPGSPPALRIPEGLARGLGSRLERDVWSAPSS--------LRLPRKASRAPRGSALGMSQRTVPGEQASYGTFQRVKYHTLSLGRKKTLPESSF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JRS4-1", "uniprot_id": "A0AC58JRS4_DANRE", "id": "A0AC58JRS4-1", "name": "ubiquitinyl hydrolase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MDSLRETRKQTIKAKSAKRKNKTHKSQKLFRRKSLKS--LGNFMSRIVKTLGTLAHLGDADQPDAA-------AEDDDGGFGDTASVHNSGNYRESS------ARKSS---SYGSVKERLSWCYGEKTPGVHEGLKNHGNTCFMNAVVQCLSNTELLAEYLGLEQYKYELNERRINGMMKS---EEVRGEVTDKLASLVRALWTNDYTPQLSVDFKSVVAKYGSQFKGNAQHDALEFLLWLLDCVHEDANLSTNNNQSRNSSSSKGSVGLEESSCPGPANS--QQPGTRHSFVQEHFQAQYRSSLTCPHCLKQSNTFDPFLCISLPIPLRQTRALNVTLVFSTEGQRFLRIGLAVPLFGSISTLRAMVAEEGKLSPDQVILTEMNSGGFQRSFSDEDDMTSISESDVIYAFQVPPHFTRGGSMRFSGYHHSLPSSPYT-ADFKGHRLPPSGTLSTEFLNHG-GSSKVLLLICNVAGSGQQATRFGPPFLMRVERTLSWDHLQQSVCNKLYVFQKTAI--IKT--TELFKVRVVGGSASCSYLSPHDSRPLCHPTVDRALKLCG-PGGPLHVKLIIEWDNKIKECLFG--NIQEEVIEDAESVRIQQQNHVQQHSCTLDDCFQLYTKEEQLAPDDAWKCPHCKQMQQGMVKMSLWTLPDILILHLKRFRQVGKR---RNKLSTLIRFPVSALDMTPHVVKRSQSMKN---------------------------LAPLPSTWKHGETDFLYDLYAVCNHHGG-MHGGHYTAYCRNSVDGHWYSYDDSSVEIVPEE----ELCTRGAYILFYQRRNVIPPWSANSSVRGSTSSSMSDHWLIRLN--GDSKRGSMVSRSSTTCPSSIADSPESPVFKNEPSIEERVSLGGFESRPFVRGIQGRSVSMRSP--TKS-----KVLPLRWSFGNKDRHKPVPASEQSP-AELVEYLESGRRPRCTKDPIVSLMTRPSDKDNDAKKTAKSSS-----------HSGLRPPEYLKIPQGQERSSSEKAMGQQPASSSRSREEGTLTRRSSRK-------SKPDQSHSRKSSGAGIQSSCSTPSGWETAQKHESSDKRDQSEDKHKKG------------QETKRHDVFAFLKGGFIKKDSLRKSRDNDSVKKADSGVKSPSGVSLSNGTHN-KNPEGKVSTMNHGSRHGSELANGKVSRGSSDIKRSQSSSNIQSKTDLGLRRTASLHRNGTSVAQP-QSVTGDRGSQSTLQRTRYSTNSLGRKKAVPESSF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E7FD00-1", "uniprot_id": "E7FD00_DANRE", "id": "E7FD00-1", "name": "ubiquitinyl hydrolase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MD------KRDKKANKDSGSKSTKRTGKLFRRKSFKS--VESLVSRILKSLGSLASGGETAE-RSD-------AEDDDGGFGESAPCAGNSVKKEDSSTSSSQVRKSSSLTSRSSAKERMFSLYGDKTPGVLG-LKNHGNTCFMNAVVQCLSNTDLLAEYLGLERYKRDVCHNGINGFIRNGNGQNEKGEVTERLAVLVRALWTFQYTPQLSAEFKMTVSKYGAQFRGNSQHDALEFLLWLLDRLHEDSTSVVPNGNNINKSKNKGQEGGDEKPGSDTLSPPQTQPGVRHSFVQEHFQAQYKSSLTCPHCLKQSNTFDPFLCISLPIPLRQTRPVCVTLVFSSKGQRYLRVGLAVPLFGSLACLRRMVADEGKIAPDQVILTEIYTTGFQRSFFDDDDLTIIAESDIIYAFQASPLYIRGGSARISGFHHSLPSSPYSSSGPEGHRLAASGALSSEFLNQTDGMLKVLLLVCNAAGAGQQAVRFGPPFLMREDRSVSWDQLQQSILSKLYYLMINGS--QAHNFRVLFKIRVVGGSASYSYLNPQDGRPLFHPAVDRALKLCG-SGGPPHVKLIVEWEHRIKDCLFG--NIQEEVVKDSESVRAQQQHHVQQHSCTLDECFELYTKEEQLAPDDAWKCPHCKQLQQGTVQMSLWTLPDILILHLKRFRQVGER---RNKLSTLVHFPLTGLDMGRHMVQRTSCARAPPG-WNK--------------------QAHRRPEASRYATDVLYDLYAVCNHHGG-MHGGHYTAYCRNSVDGQWYTYDDSSVEPLQEG----EVCTRAAYILFYQRRDAIPSWSASCSRQGSSSSSLSDHWLIRLN--ADEGISNSTSKVSNSSSAPEPQTPHSPVIHKSANEDNRDVA---EATPFVRSVRGQSMSMRYQ--SKSKTGSGKVLPLRWSFASKERRKPPSITSQNDNDELVEYLESGRRPRCTKEPIVSIVASPSQVKGHLREDDSLSSPSCCSSLNGVERSSSQGPDSPKVPEGQSRPTSDLNAVSSVDSRAKKCSKTTRQEHERTQ-------ASKSLQGSPTALSTGNSTSHSRDSTLKRLRNPAAATSRIHPSQILMAT------------GESRGKDGIHPVSSTSQLQDGCSKEVGHG--KTLSS--KSLTKLSLSNGTLNGKVVEVRKTGTVHKSTSKTNGRDTQVFSNTIDMKRAHSSSNIQNRLDMTLKRTLSLQRNGPLVPASNKGLAVDKSSYATLQRIKYSSTSLGRQRPVPESCF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W117-1", "uniprot_id": "Q9W117_DROME", "id": "Q9W117-1", "name": "ubiquitinyl hydrolase 1", "aln": "MGTTKERREQSEGDAATTHLTTTATATTGAIVAAGVTTTLPATKTTTTAADTSTTNAAKKIRRTFSMPRNPFRWTRKFKTAVAVTSSAGAENDNESGKNNGARERRGSHTAISSCVGGGRGRSGSIVSLSSYEAPFISSTNNNTTTASNGNNNNSSSSNINSKRTRALRRSSFRKFLNRIAQHLSSTVNVVSEEKHSPANRIAFIEIVPFYTGCWRRKEANKHGQPSVSGSSSGGGGGAGGPGGGERVPPIGGYQWPADQTPGVMG-LKNHGNTCFMNAVLQCLSHTDILAEYFVLDQYKADLKRRNKINSRKFG----TKGELTEQLANVLKALWTCKNESDHSTSFKAVVDRYGTQFRSSTQHDAQEFLFWLLDKVHEDLNTASKRRYKSLKNS------YGRSDEVIAAETLANHIRCNNSFVQAVFQAQFRSSLTCPRCEKQSNTFDPFHCISVQLPQLTQQTIFVTVVYMTRLPRQVRMGLRVPAGSPIVALREQLQADTGIEGSRMVLVDLNAEGFTRVFYDTQPVETLSSIETIYCIEVPAATPVAKAATPSETGDKSAPTAVTPSPAAAQSQADLLLLVAN---------------VYRAKDGADITRFGAPFSMKAPRDCSYQDLQKRMLREMAPLLKPEVFSYATPLAEMFRIRLQDPSADPDTYLEQVEHPLLTEMIDMALSVLSSEAGPQHIKLLLEWSSPEAHFISKQQDTEEAVVEHESVARLSASKPSDTAALTLEQCLEHYTKAETLSAEDAWRCPHCQQYLPVVKTLGLWSLPDILVVHFKRFRQHQSKGPQAAKLTTMVKFPLTAFDMSPHLARGVHESASSSLGMGTGIGLGLGLGSNPWKKARSVDSRSSTLNSRCDAKDTRYDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQRVSKVPEDDIEQDIINNEAYMLFYQRR------SVDAGECSGSSSNSGDHWVSRIAPASSSSASSTSGKEREPVKLEENTESPAAVEVTEKAQS--------KPVDIVCQDKAKGTADGPDADQEQTTVPHDLQIEELAFADADVDTSLGET-----IKAEVNLAAKDEPKKVEVEEATPIFAMDEDGSEARQEKKEECVK-------------KEDELSEAPDVSELTAESKTNGHVSSSSSSSSSESSLSSRSSPR-----------------SLSTSVTAASTLQSKFNGHMSAAPALFNGNGNTS-------------------------QLSSSLQLSRHVLHNHQWHGSRSSVS---------AVENATQHQQQQAAASLSLRHSFSTSSNYTETLSSLLRKSANTCSKDT-------LLFIDQQSHHHTAGLIEDDDDSYMGRSLWISPVTPHKLITVSPKN---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * :::: :..*: * : . * . . . :.**. *************:****:*::***:: * :*: :.*:*::** :::**** . .: *..** .* :**:**:..:**** ***:**** :*** . . . **** ****::******:* ********* *:*: :* : : **:*: :. * :*:** ** ..: ** : : : ..::*.:: . ** * * * : : ::. : :*.::... . : . :. . .: . * :: . * : ***.** :: * *: .**: : :: : :* :*: . * . : :** :* .* : .** *:** :**. . : . :* :. . . . . : : **::*:: *** * *: :***:****: :.**:*****::*:*** * .: **:*:::**::.::* *:.: * ******* *:*. :. ***** *:*. * :**.:**. *. : * :: .. **:****:* *.... ..:**. .***: *: .. .. . . . :.: . . :. :* .:. : . . . :*. : . : : * : .*: .. .. : . . : .. : . : : . * . .: : : . :: . . . .. : : * . ... : : * . ", "identical_positions": 209, "similar_positions": 266, "identity": "14.96%" }, { "cls_id": "homologset.agr.MGI:2444552", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZRN3-1", "uniprot_id": "D3ZRN3_RAT", "id": "D3ZRN3-1", "name": "", "aln": "MVDDELGALVVDNGSGMCKAGFGGDDAPRAVFPSMVGRPRHQGVMVGMGQKDCYVGDEAQSKRGILTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYVAIQAVLSLYASGRTTGNVMDSGDGVTHTVPIYEGYALPHGILRLDLAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVTAAASSSLERSYELPDGQVITIGNERFRCPEAIFQPSFLGIESRGIHETTFNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIVTLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFZ3-1", "uniprot_id": "ACTBL_MOUSE", "id": "Q8BFZ3-1", "name": "Beta-actin-like protein 2", "aln": "MVDDELTALVVDNGSGMCKAGFGGDDAPRAVFPSMVGRPRHQGVMVGMGQKDCYVGDEAQSKRGILTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVTAAASSSLERSYELPDGQVITIGNERFRCPEAIFQPSFLGIESRGIHETTFNSIMKCDVDIRKDLFANTVLSGGSTMYPGIADRMQKEIVTLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q562R1-1", "uniprot_id": "ACTBL_HUMAN", "id": "Q562R1-1", "name": "Beta-actin-like protein 2", "aln": "MTDNELSALVVDNGSGMCKAGFGGDDAPRAVFPSMIGRPRHQGVMVGMGQKDCYVGDEAQSKRGVLTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHIVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVRAAASSSPERSYELPDGQVITIGNERFRCPEAIFQPSFLGIESSGIHETTFNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIITLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60010-1", "uniprot_id": "ACT_YEAST", "id": "P60010-1", "name": "Actin", "aln": "-MDSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*: ***:***********.***********::*******:********.***********:***:******:***********:***********:***:******:*** ***********:**.**:**:********:****** *:******** **** *::***.***:***************:****.*:**********:*************** ** *** *:******************.***:*:**.**:** **.:**:*********:**:*:.* *:***:**:****:****** :****:**:**********************:**************:**.***:***", "identical_positions": 309, "similar_positions": 53, "identity": "82.18%" }, { "cls_id": "homologset.agr.MGI:2444554", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BKH7-1", "uniprot_id": "SIN1_MOUSE", "id": "Q8BKH7-1", "name": "Target of rapamycin complex 2 subunit MAPKAP1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFLDNPTIILAHIRQSHVTSDDTG------MCEMVLIDHDVDLEKTHPPSVPGDSGSEVQGSSGETQG-------------------------------------YIYAQSVDITSS------WDFGIRR-RSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQ--------------------------------------------------------------ELKS-----LFEKKSLKEKPPSS---------------------------------------------------------GKQSILSVRLEQC-------------------------------PLQLNNPFN--------------EYSKFDGKGHVGTTATKKIDVYLPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDN---------VSAYCLHIAEDDGEVDTD-FPPLDSNEPIHKFGFSTLALVEKYSSPGLT----------SKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRKGSQKISGPQYRLEKQSEPNIAVDLESTLES--QNAWEFCLVRE---NSSRA--------------DGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIH------------------------------------------------RLRFTTDVQLGISGDKVEIDPVTNQKASTK-------------FWIKQKPISIDCDLLCACDLAEEKSPSHA-------------------VFKLTYLS--SHDYKHLYFESD-------------AATVSEIVLKVNYILESRASTARADYLAQKQRKLNRRTSFSFQKEKKSGQQ--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AYF1-1", "uniprot_id": "SIN1_RAT", "id": "Q6AYF1-1", "name": "Target of rapamycin complex 2 subunit MAPKAP1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFLDNPTIILAHIRQSHVTSDDTG------MCEMVLIDHDVDLEKTHPPSVPGDSGSEVQGSSGETQG-------------------------------------YIYAQSVDITSS------WDFGIRR-RSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQ--------------------------------------------------------------ELKS-----LFEKKSLKEKPPSS---------------------------------------------------------GKQSILSVRLEQC-------------------------------PLQLNNPFN--------------EYSKFDGKGHVGTTATKKIDVYLPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDN---------VSAYCLHIAEDDGEVDTD-FPPLDSNEPIHKFGFSTLALVEKYSSPGLT----------SKESLFVRINAAHGFSLIQVDNTKVTMKEILLKALKRRKGSQKISGPQYRLEKQSEPNIGVDLESTLES--QNAWEFCLVRE---NSSRA--------------DGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIH------------------------------------------------RLRFTTDVQLGISGDKVEIDPVTNQKASTK-------------FWIKQKPISIDCDLLCACDLAEEKSPSHA-------------------VFKLTYLS--SHDYKHLYFESD-------------AATVSEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BPZ7-1", "uniprot_id": "SIN1_HUMAN", "id": "Q9BPZ7-1", "name": "Target of rapamycin complex 2 subunit MAPKAP1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFLDNPTIILAHIRQSHVTSDDTG------MCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGETQG-------------------------------------YVYAQSVDITSS------WDFGIRR-RSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQ--------------------------------------------------------------ELKS-----LFEKKSLKEKPPIS---------------------------------------------------------GKQSILSVRLEQC-------------------------------PLQLNNPFN--------------EYSKFDGKGHVGTTATKKIDVYLPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDN---------VSAYCLHIAEDDGEVDTD-FPPLDSNEPIHKFGFSTLALVEKYSSPGLT----------SKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRKGSQKVSGPQYRLEKQSEPNVAVDLDSTLES--QSAWEFCLVRE---NSSRA--------------DGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIH------------------------------------------------RLRFTTDVQLGISGDKVEIDPVTNQKASTK-------------FWIKQKPISIDSDLLCACDLAEEKSPSHA-------------------IFKLTYLS--NHDYKHLYFESD-------------AATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZP2-1", "uniprot_id": "E7EZP2_DANRE", "id": "E7EZP2-1", "name": "Target of rapamycin complex 2 subunit MAPKAP1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFLDNPAIILAHIRQSHVTSDDTG------MCEMVLIDHDVDLEKCHLSAASAGGGS-SGGSYGDSSGGG------------------------------VDGQTCDLSQSVDITSS------WDFGIRR-RSNTAQRLERLRKERQNQIKCKNIQWKERSSSQSAD--------------------------------------------------------------DLSS-----LFEKKDFKDRPRST---------------------------------------------------------GSKSTLSLRLEQC-------------------------------PQQLNNPFN--------------EYSKFDGKGHVGTTATKKIDVYLSMQSTQEKLHPMTVVTMANARVHDLIGLICWQYTCEGREPKLTEN---------VNTYCLHIAEDDGEVDTD-FPPLDSNEPIHKFGFSTLALVEKYSSPGLG----------PKQSLFVRINAAHGFSLIPVDSLKVTMKDILQKALKKRKGSQKGSGPLYRLEKQMEPNVAVDLDSSLEN--QGTLEFCLVRE---NSSRG--------------EESSEEDPPIDITTVQDMLSSHHYKSFKISMIH------------------------------------------------KLRFTTDVQLGISGEKVEIDPVTNQKTSTK-------------FWIRQKPISIDSDLLCACDLVEEKSPNHA-------------------IFKLTYLS--NHDYKALYFECD-------------AATVNEIVLKVNYILESRASTSRADYFAQKQRKLSRRTSFSFQKDKKSGQ---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V719-1", "uniprot_id": "SIN1_DROME", "id": "Q9V719-1", "name": "Stress-activated map kinase-interacting protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATYSNQHWLLSHIRNSFISTDDTG------MCETVMLSDDMPKHYLRKFGNSGAGGDHYHWRRAHKTPPTGGGTTPERNTRHPDAPLQEVDFICYPGLDLSDDEEDMSTHSFDIQMY------PEVGAHRFRSNTAQKLEKLDIAKRRAARIKSVNYQEEVQPPESD--------------------------------------------------------------DFFKRKELPLSKAERVKNEPKAND--------------------------------------------------DDLSDEGVQSQLTEQLAKS-------------------------------PKQAQNRFI--------------EFARFDGTSQVG-MQTKRINVFLNMLPEPDRNYPLKICVVATAKIQEVIGFVCYRTSLQYPDVPLKS----------LQHYALYMTEDN-DDMED-FPPLDNREPCSKFGFSQLTLAERRPLAPVTR-------VDYHSQLGSKSMTSVEDKTALSDAAVKALQNISLNGGTSDPGGGGGGGDSPHDNVKEYEKRLLNHNDMLEAPMHRTFRLNIIDKRFFKSDVT--------------LGISGERIEIDQCKNAKFWPQKKPVSTPIDFVA------------------------------------------------HCEILERRHLKALLRIWLKSNSSSPSFSTG-------------CTSAPINASVTTLNAGSGSGGIAHSPSSP-------------------GHSSGLFSSSNIRFKHYDFDTD-------------THTAEQIHNKLNCILEMRSSDLRREFLLQRDRKQEKRQLKL------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08236-1", "uniprot_id": "AVO1_YEAST", "id": "Q08236-1", "name": "Target of rapamycin complex 2 subunit AVO1", "aln": "MDTVTVLNELRAQFLRVCPEKDQMKRIIKPYIPVDEFNTEQCLDSSIRELYMNSDGVSLLPELESPPVSKDFMENYASLGKMRIMRENEGQKGKANQNLIGAEKTERDEEETRNLQDKSAKNTLIVEENGTLRYNPLNSSASNSLLNDDDHTSGKHHKTSSKEDSYLNSSMEMQKKSSKRSSLPFVRIFKSRRDHSNTSGNKNVMNTTNTRAKSSTLHPPGARHNKKGSKFDMNFDFDENLEEEDDDDDDDEEGDDIHSQFFQLDDDFDAKGSGASPAHKGINGMSNNKNNTYTNNRNSISILDDRESSNGNIGSASRLKSHFPTSQKGKIFLTDNKNDGQKSDSLNANKGIHGDGSSASGNGSVSRDGLTETESNNISDMESYINEKDLDDLNFDTVTSNINKTVSDLGGHESTNDGTAVMNRDSKDSRSNSNEFNAQNRDRITPGSSYGKSLLGSEYSEERYSNNDSSTMESGEMSLDSDMQTNTIPSHSIPMSMQKYGIYHGDDDSTLNNVFDKAVLTMNSSRHPKERRDTVISGKEPTSLTSSNRKFSVSSNLTSTRSPLLRGHGRTSSTASSEHMKAPKVSDSVLHRARKSTLTLKQDHSQPSVPSSVHKSSKEGNILIEKTTDYLVSKPKASQLSNMFNKKKKRTNTNSVDVLEYFSFVCGDKVPNYESMGLEIYIQASKKYKR-NSFTTKVRKSSTIFEVIGFALFLYSTEKKPDNFEEDGLTVEDISNPNNFSLKIVDEDGEPFEDNFGKLDRKSTIQSISDSEVVLCKVDDAEKSQNEIETPLPFETGGGLMDASTLDANSSHDTTDGTINQLSFYKPIIGNEDDIDKTNGSKIIDVTVYLYPNVNPKFNYTTISVLVTSHINDILVKYCKMKNMDPNEYALKVLGKNYILDLNDTVLRLDGINKVELISKKDARELHLEKMKPDLKKPVLPTIQSNDLTPLTLEPLNSYLKADAGGAVAAIPENTKVTSKAKKISTKYKLGLAKQHSSSSVASGSVSTAGGLANGNGFFKNKNSSKSSLHGTLQFHNINRSQSTMEHTPDTPNGVGDNFQDLFTGAYHKYKVWRRQQMSFINKHERTLAIDGDYIYIVPPEGRIHWHDNVKTKSLHISQVVLVKKSKRVPEHFKIFVRREGQDDIKRYYFEAVSGQECTEIVTRLQNLLSAYRMNHK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* :: *:* ** . : .. . : ... . ..* :.* :. .: : ::: : . . : ::. .: :. . : . . *:. . :* *: : :. . * .* * *: * .:* : ::::: .: .:. . .: : ::**: : : : : . . :.* :.::: : * * ** ... .:. * :.* : * . * :. . . .. : . : : :: : .. :* . .: ..:. . :. : .: :* . :. :: :: . ::*. . :* . : :: * ... ::. :: : * :.: *: : ", "identical_positions": 34, "similar_positions": 158, "identity": "2.89%" }, { "cls_id": "homologset.agr.MGI:2444555", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHH5-1", "uniprot_id": "D3ZHH5_RAT", "id": "D3ZHH5-1", "name": "", "aln": "MDSKTCESKKEDLLS-SGVISKGGSSSPFFVTSTHGAIIENTSSAGTLTQIPFFPKYEVELDSPRKSTSYPGKEHIERVLEEYSQQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEELRNQLQNTVHELEAAKSLKEDMLKDSSTQIEQLRKLMLSHEGVLQDIRSVLVDFEEASGKKICEHDSMSTMHFRSLGSAISKILRELDTEISFLKGRIFPVEDQLETLKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSVQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELRETKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKNECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMNLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALRLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRKLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIRQERDQLLNEVKTSRTELNNLSEDYEVLKRNFRNKSEEMESTTNRLKMQLKSAQSELEQTRNTLKTMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKVQFLEEAVTSANKEKHFLKEEKSKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPGYTSNSSMKPRLLQPASVARSHSNVPSSQSTASFLSHHSLKTNTLKEDPTRDLKQLLQELRSVINEEPAMPLSKTEEE--TPSLGALEDRVRDCITDSSLRSELCHRSNNSLRESTEGSKSSETLSREPVALHPGDLEDPSSCFTFTSTASPSVKISASRSFNSSPKKSPVHSLLTSSAEESVGSTPQYRSAKPVHSSNSAKDSQSPSLETTGKTCRKLQNRLESLQTLVEDLQLKNQAMSSMIRNQEKRIQKVKDQEKMLLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CDI6-1", "uniprot_id": "CD158_MOUSE", "id": "Q8CDI6-1", "name": "Coiled-coil domain-containing protein 158", "aln": "MESKACESKNEDLLP-SGITSKGGSSSPFFVTSTHGTIIENTSSTGTLTQMPFFPKYEVELDSPRKSTPYPGKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEESRNQLQNTVRELEAAKCLKEDMLKDSSTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKICEHDSMSTMHFRSLGSAISKILRELDTEISFLKGRIFPVEDQLETLKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSVQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELRESKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMNLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRKLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIRHERDQLLNEVKTSRTELNHLSEDYEVLKRNFRNKSEEMESTTNRLKMQLKSAQSELEQTRNTLKTMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKVQFLEEAVTSANKERHFLKEEKSKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDK----FAECQDIIQRQEQESVRLKLQHTLDVKELQGPGYTSNSSVKPRLLQPASVTRSHSNIPSSQSTTSFLSHHSIKTNTPKEDPTRDLKQLLQELRTVINEEPAMALSKTEEDGRTPSLGALEDRVRDCITESSLRAELCHRSNNSLRESTEGSKSSETLSREPVPLHPGDLEDPSSCFTFTSTASPSGKMSASRSFSSSPKKSPVHSLLTSSAEESVNSTPQYRSTKPIHSPTSAKDSQSPSLETTGKTCQKLQNRLESLQTLVEDLQLKNQAMSSMIRNQEKRIQKVKDQEKMLLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5M9N0-1", "uniprot_id": "CD158_HUMAN", "id": "Q5M9N0-1", "name": "Coiled-coil domain-containing protein 158", "aln": "MESKAWESNNEDLLSSSGVTSNGGSSSSFFVSSIRGTIIENTSSAGTLTQVPFFPKYEVELDSPRKIIPSPGKEHFERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLKDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKICEHDSMSTLHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQMEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKTEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDNRNMEVQRLEALLKALKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTISDLTTSLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRMELKELKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRSELNNLSEEYEVLKRNFRNKSEEMEMTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKSKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVTNMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDIKELQGPGYTSNSSLKPRLLQPASVTRSHSNVPSSQSTASFLSHHSTKANTLKEDPTRDLKQLLQELRSVINEEPAVSLSKTEEDG-RTSLGALEDRVRDCITESSLRSDMCHRSNNSLRDSTEGSKSSETLSREPVTLHAGDREDPSGCFTFTSAASPSVKNSASRSFNSSPKKSPVHSLLTSSVEGSIGSTSQYRSAKPIHSSDSVKDSQSPPIETTGKTCRKLQNRLESLQTLVEDLQLKNQAMSSMIRNQEKRIQKVKDQEKMLLK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**: **::****. **: *:*****.***:* :*:*******:*****:*************** . *****:********:********************************************************: ********:******.*********.********:*********:***:********************:*********************:*************:***********************************************:***:**********************************:******* ******************************************************************************:**************:*.*************************************************.*******:****:**************************************************:***:********************************************::**:*:******************************************::*************:***:***:**************** ***:********************:********************************:******:*.****:******************************************:******** *************************:*************:**********:*****:******:******* *:** ****************:*******:.******: .**************:****:::*********:****************.**.** ****.******:**** * ******.***************.* *:.**.****:**:**. *.******.:*******:**********************************************", "identical_positions": 1005, "similar_positions": 85, "identity": "90.22%" }, { "cls_id": "homologset.agr.MGI:2444557", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C2N5-1", "uniprot_id": "KMT5B_RAT", "id": "P0C2N5-1", "name": "Histone-lysine N-methyltransferase KMT5B", "aln": "--------------------------------------------------------------MKWLGDSKNMVVNGRRNGSKLSNDHQQNQSKLQ-HAGKDALKTGRNAVERRPNRCHGNSGFEGQ-----------------SRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHISKADSFSHNNPMRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSE-QNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSR-----------VGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKSSDSQSVSSNTDADTTQEKDNATSNRK-----------------SSVGVKKNSKSRALTRQSMPRVPAASNSTSPKLVHMNNSRVPKKLRKPAKPLLSKIKLRNHCKRLDQKSTSRKLEMGNLVLKEPKVVLYKNLPIKKEREAEGPVHAAVGSGCLTRHAAREHRQNPGRGAHSQGDSLPCTYTTRRSLRTRTGLKETTDIKLAPSPLDGYKNGILEPYPDSGQ--QPTPEVL-EELAPETALREEASQECPKSDSCPSRKKFRQGKPVKHLAKTEDCSPEHSFPGKD-GLPDLPGPHPDQGEPSGTVRVPVSYTDSAPSPVGCSIVTPDSFTTKDSFRTAQSKKKRRVTRYDAQLILENSSGIPKLTLRRRHDSSSKTND-HESDSVNSSKISIKLSKDHESD-SNLYVAKLS-----------------------------------------NGVSSGPGSSS-------------------------------TKLKIQLKR--------------DEESRGPCAEGLHENGVCCS----DPLSLLESQMEVDDYSQYEEDSTDDSSSSEGEEEEEDCEDDFDDDFIPLPP-------------------------------------AKRLRLIVGKDSIDIDISSRRREDQSLRLNA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U8K7-1", "uniprot_id": "KMT5B_MOUSE", "id": "Q3U8K7-1", "name": "Histone-lysine N-methyltransferase KMT5B", "aln": "--------------------------------------------------------------MKWLGDSKNMVVNGRRNGGKLSNDHQQNQSKLQQHSGKDTLKTGRNAVERRSSRCHGNSGFEGQ-----------------SRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHISKADSFSHNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSE-QNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSR-----------VGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKDNATSNRK-----------------SSVGVKKSSKSRALTRPSMPRVPAASNSTSPKLVHTNNPRVPKKLRKPAKPLLSKIRLRNHCKRLDQKSASRKLEMGSLVLKEPKVVLYKNLPIKKEREPEGPAHAAVGSGCLTRHAAREHRQNHGRGAHSQGDSLPCTYTTRRSLRTRTGLKETTDIKLEPSPLDGYKNGILEPCPDSGQ--QPTPEVL-EELAPETAHREEASQECPKNDSCLSRKKFRQVKPVKHLAKTEDCSPEHSFPGKD-GLPDLPGSHPDQGEPSGTVRVPVSHTDSAPSPVGCSVVAPDSFT-KDSFRTAQSKKKRRVTRYDAQLILENSSGIPKLTLRRRHDSSSKTND-HESDGVNSSKISIKLSKDHDSD-SNLYVAKLS-----------------------------------------NGVSAGPGSSS-------------------------------TKLKIQLKR--------------DEESRGPCAEGLHENGVCCS----DPLSLLESQMEVDDYSQYEEDSTDESSSSEGEEEEEDCEDDFDDDFIPLPP-------------------------------------AKRLRLIVGKDSIDIDISSRRREDQSLRLNA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4FZB7-1", "uniprot_id": "KMT5B_HUMAN", "id": "Q4FZB7-1", "name": "Histone-lysine N-methyltransferase KMT5B", "aln": "--------------------------------------------------------------MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQ-HTGKDTLKAGKNAVERRSNRCNGNSGFEGQ-----------------SRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFSHNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSE-QNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSR-----------VGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRK-----------------SSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA--KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTND-QENDGMNSSKISIKLSKDHDND-NNLYVAKLN-----------------------------------------NGFNSGSGSSS-------------------------------TKLKIQLKR--------------DEENRGSYTEGLHENGVCCS----DPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPP-------------------------------------AKRLRLIVGKDSIDIDISSRRREDQSLRLNA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3H2-1", "uniprot_id": "KMT5B_DANRE", "id": "Q5U3H2-1", "name": "Histone-lysine N-methyltransferase KMT5B", "aln": "-----------------------------------------------------------------MGESKNMVLNGRRHGRKFSSNQPVSKSRLQNTQRSHLRQNKGSPSVRRCSRRCGGAPPEAE-----------------RRHVPSSGMTAKELCEYDDLSTSLILDPYLGFQTHKMNT-----------------------RFRPIKGRQRELREIIELFKKHDNLEKAFQALTSGDWTRHHFLNKTKSQEKLFKAHVFVYLRMFASDSGFEILSCNRYSSE-QNGAKIVATKDWKRNDKIEHLVGCIAELSPSEERMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKVLRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSK-----------PGLPVEAPVINSKYGLRETDKRLNRLKKLGESCRNSDSQSVSSNAEADSQEPTTVQTSLRKR---------------TSQSCVKKHGEAKAVTRQTLSSTPSS--TSSSKRSQANISSLPKRLKSKPTQTLSKGRRR--CRGLWTKGSSRVSASG-------------NLKESSRRDTDRRRSASKGS----VARSSENNRSSSKGASPCKDSTLCPYRTRRSTRTSLGAQGAEGTEASNHPAS--PSIVLKSEP--GE---FIPVTLGHQMSTPSLD-----SSCPKKGTCPRRRR-----TVKQEDSYGESFVQEG-------VPDLR-HAVRAADVADCGKVVLGLPDRHQHYNGSSKSS-------KALRRGKGKKKRQITRYDAQLILQNNSGIPKITLRRRRDSSSSKNEPRETSSSSSSKISIKFSKEHEKDRSSSYVAKLN-----------------------------------------NGFSHGPHSSS-------------------------------TKLKIQLKR--------------EED-----PASLHRTYPEDV----TLGIVQRDAADVLDHKAAAQVGQDMEVESMSSEDDDDDYFDNEDDFIPLPP-------------------------------------AKRLRLIVGKDSIDIDISSRRREDQSLRLNA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W5E0-1", "uniprot_id": "SUV42_DROME", "id": "Q9W5E0-1", "name": "Histone-lysine N-methyltransferase Suv4-20", "aln": "MVVGSNHTRRGETGSRFTNSSSSSSTSGGPTASASSTTSVTSSLATNSTSTSTAAALLSSMSHKSHGPPPSAPPSAHHQTNQQHHQVAHSQPHATHYQQTNQHPSHHHQSHQSSNGSGGGSAGSGSGSGSVVSGLNGCNGSAVSRLSQSTGMSPRELSENDDLATSLILDPHLGFQTHKMNIR-----------------------FRPLKVDTQQLKAIVDDFIHTQNYDIAIQRIYEGPWIPRHLKNKNKIATKRLHDHIVRYLRVFDKDSGFAIEACYRYTLEEQRGAKISSTKRWSKNDKIECLVGCIAELTEAEEAALLHSGKNDFSVMYSCRKNCAQLWLGPAAYINHDCRANCKFLATGRDTACVKVLRDIEVGEEITCFYGEDFFGDSNRYCECETCERRGTGAFAGKDDGLMLGLSMGLGLASSGPGNNGGYRLRETDNRINRIKSRANSTNSTSNSNSNTNDSTGPSETSSTNGLVASGGAGGATGAAMLPTPSQQSTGGKEATAAVSLLEKKLPNVVVSP-LTMKELRQKGMTKYDAEMIMANAAYQQQHHHQHHFHHHHHHHHHHHNHGQHASTGAEATAAVQQMAAMQKPGVGGTGAAGNAGATTVSSVAAGAGSEVNGGRSTSLRKSMRVNSTSSSISTASADEVIAPVVAASISLPSKAPVVLMPRCKPAQMAIAALHQSQQRQLRRSERQKEKLTDGESSDTSSEQQKKEQKQQDHQLPQKMFSLAEEPQPEKS-EEKQQEQQKRVTRNSAGRVGLVARLATAHNNNIATTTNSSSSSNKATTITNCNNHNSNNSSRINHNSNLSSRLSVKSRKPAPSEASSIPSSTSSENQQQQATRRSCSPTPAYKKNLLASFDPDPPSTQGIKEQLKDESVTYSPVKQKRSRRAAALAAAQSIHCEALGGFPTGSTGSQRKRAQAGEPTTSCSSTTISNVEPLLKTPERRLKLTLRMKRSPILDEVIELGTSLSNGGAGRGAPGSHREGTAGEGSVRSALNLTGSSSNGIEYEILRMEGISEHGNDDDEDEEEDDEEPAAEEEEEPPPKEELQLVNKKQRKKQRSRSRSSQRRSPAPSSVYGTPQKKRLRLIFGNESHTIDIPPAAAEGSGSGLDDLNSSGGGGDESFNASYASSTSLTVNTSSSSTSSSSGVGGATSTSAEPVDSSTVGPPIAAQSPSSTTSSSFQSACTSTTNSNSYFPNGKQRAAGEDSYAMHYYQLGKFAGTPSPGQGQAIVSSSSGSSGGGGSGAGFLSMPKHTFGTCALLAPTSFACLQNQPQISQQKTSSGGGAGVVPTSTSTGAVTSHHHTNNHHGQK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . ..::: : : .:.: .. : . *.: ... * *:**:.:**.* ***:***:***:********* ***:* .:*: ::: * : :: : *:: : .* * ::: **.* * :: *:. ***:* .**** * .* **: * *.**** :** *.:***** ********: ** **: *:******** *************:******.****::*********.***** ****:*:**:.***:.*.:*** ********** .: **. .* *. * *****:*:**:*. .:* ..:.... .:* .:.. : . . .. *: : :: . .:. : : : : . . .: .: : : : : : :: . *. .. : . * . . * * * : . : . .: .. : . ...: ::: :: . . . : : :. : . . : : :: :.::... :* : : *.. .: . . . ** .. *.. .::: * . : :..: : .. .*. *. .*. **.:::** .: . . *. : . : ::. . . .. ..::::* :: ** ******.*::* ***.. *... *: ", "identical_positions": 201, "similar_positions": 247, "identity": "15.17%" }, { "cls_id": "homologset.agr.MGI:2444559", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P5G0-1", "uniprot_id": "MK04_MOUSE", "id": "Q6P5G0-1", "name": "Mitogen-activated protein kinase 4", "aln": "------------------MAEKGDCIASVYGYDLGGRFIDFQPLGFGVNGLVLSATD--SRACRKVAVKKIV--LSDARSMKHALREIKIIRRLD-HDNIVKVYEVLGPKGSDLQGELFKFSVAYIVQEYMETDLACLLEQ-GTLTEDHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLAR-----IVDQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGKMLFAGAHELEQMQLILDTIPVVREEDKEELLRVMPSFVS----STWEVKRPLRKLLPDVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAASQSQ--LSNWD----RYPVSLSSDLEW-RPDRC-----------QDASEVQRDPRAGSTPLAEDVQVDPRKDSQSS-SERFLEQSHSSMERAF----EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAASAPPRAAVAADPVSREDEPASLFLEIAQWVKSTQSGSERASPPPD-------------------------------------APEPRLSASP---PGHPTPIDGGAS-----------------------PQFDLDVFISRALKLCTKP------EDLPENKLGDLNGACISEHPG-------DLVQTEAFSKERW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31152-1", "uniprot_id": "MK04_HUMAN", "id": "P31152-1", "name": "Mitogen-activated protein kinase 4", "aln": "------------------MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVD--SRACRKVAVKKIA--LSDARSMKHALREIKIIRRLD-HDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQ-GTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLAR-----IVDQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDKDELLRVMPSFVS----STWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQ--LSNWDTCSSRYPVSLSSDLEW-RPDRC-----------QDASEVQRDPRAGSAPLAEDVQVDPRKDSHSS-SERFLEQSHSSMERAF----EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTGAREDEPASLFLEIAQWVKSTQGGPEHASPPAD-------------------------------------DPERRLSASP---PGRPAPVDGGAS-----------------------PQFDLDVFISRALKLCTKP------EDLPDNKLGDLNGACIPEHPG-------DLVQTEAFSKERW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63454-1", "uniprot_id": "MK04_RAT", "id": "Q63454-1", "name": "Mitogen-activated protein kinase 4", "aln": "--------------------------------------------GCGGNGLVLSATD--SRACRKVAVKKIV--LSDARSMKHALREIKIIRRLD-HDNIVKVYEVLGPKGSDLQGELFKFSVAYIVQEYMETDLACLLEQ-GTLTEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLAR-----IADQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGKMLFAGAHELEQMQLILDTIPVVREEDKEELLRVMPSFVS----STWEVKRPLRKLLPDVNREAIDFLEKILTFSPMDR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B0V360-1", "uniprot_id": "B0V360_DANRE", "id": "B0V360-1", "name": "Mitogen-activated protein kinase 4", "aln": "------------------MAWHN-TSPFRYGFDLGAQYQDLRPLGTGASGLVLSALD--RRSGLRVAVKKLV--MRDAVSVKHALREVKITRRLQ-HENVVRVYDVLGSSGHPLPRDLTHVAAIYIVQECMETDLARLLEQ-GPLPAEHATLLFYQLLRGLKFIHSANVLHRDLKPANIFINTEQMLLKIGDFGLAR-----IVDPHYSHKGYLSEGMVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILDTVPVIREEDRQELLRVMPSLVG----HGWQIRRSFRDLMPEVEDKAIDFLESILTFNPMDRLTAEAALCQPFLQRYSCPQDEPVSLQPFRIEDELEDSLVTESTHTHGLRSHWD----RYDSSLSSDVYWPTQDQCGCMQSVSELGEAEDEEVQRDPRASSASHIEEAQVDPRKYSHSSSAERFLEQSHPSLERICGHFSELDCGRSCDYKVGSPSYLDKIAWREGKPQHYSEPKLILDLSNWRNNSMAAPRQNSAEKLLT---EPGDLFQEISRWVESTQSGLHSPGSPQEPPSSPCSPPLPLSPTLMPQSQIQIPAPLTLPSPLSRRSPTPFFSAPPSLLPSSPSSPHHGSSNYPSSSIGCENYEEPSQMRPSGEEHFDLDVFISQALQICSQSEIMESSDDLKSDNISDVCNVSDDHRPSRTQTPTPEMVKAHGCHKEHW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41808-1", "uniprot_id": "SMK1_YEAST", "id": "P41808-1", "name": "Sporulation-specific mitogen-activated protein kinase SMK1", "aln": "MNCTLTDNTRAINVASNLGAPQQRTIFAKERISIPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDG-------LYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLN-GCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLGKNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQGP-------------------------------------------------------------FDFTYESELNSMSKLRDYLVEEVKNFKTDLSSSSL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * * *. . ::****: : . :*:*:**:*: . :. *.*:*.: :: .. * ** :: *** ::.. *. * . ::**:* ***:****:*:******.**: . : *** ****** : . * : : :::: :.*:***:*.**** : *:*::*:**.******: : : :* * ..:.*: *:..: . :: :: : . :. : . .::* .. :**:::*.:* :.. .* ", "identical_positions": 84, "similar_positions": 99, "identity": "11.75%" }, { "cls_id": "homologset.agr.MGI:2444560", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZH78-1", "uniprot_id": "D3ZH78_RAT", "id": "D3ZH78-1", "name": "", "aln": "--MSSSHPEPGAREPQSPRPQPLSQSSSSLLCEGREQRPELRKSVSSTVWRAQQAEASTGPRTLQEEGCQMESTEQAQTANPPSQAAAGGHWRSSTVGNVSTMGIGDLCRLQAPSVAAVQRSHSDLVHSTQTRGHGSVQKPSLSCSALGISPVHRAHLQPGGVAGQGGPTPAPLPSDSSLEDGTSKSACTLGESQVWVPTIELEDTTGLLIGSQGEPQATGQPSTTPCHALPPATLLCTVGEAVPGSTCHALPAKGILAFPKLVASVSESGLQAQCGMKFHCQLSGGISGRAHCCVHPWGPTGLATESGSRTKDVWTMTSATDLALGVAS---AQDAGVQAAPVAACKAVATSPSLEAPKTLNIFPEVMLGPGLEEASSPVREVRWDAEGMTWEVYGASVDPEVLGIAIQKHLEMQFEQLQQAPASE---DSLSTEGRRGPLR----AVMQSLRRPSCCGCSGAAPE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A2I3BRN2-1", "uniprot_id": "A0A2I3BRN2_MOUSE", "id": "A0A2I3BRN2-1", "name": "", "aln": "--MSSSHPEPGAREPQSPRPQALSQSSSSLLCEGREQKPELRKSASSTVWRAQQGEAGSSPRILQEEACQTEIPEHAQTASTASQAGAGGHWRSSTVGNVSTMGIGDLCRLRAPSVAAVQRSHSDLVHSTQTRGHGGVQKPSLSCSALGSSPVHRAQLQPGSVAGQGGQTPAPLQSDSAPEDGTSKSACTLGESQVWVPTVELEDATGLLRGPQGEPKATGQPPTTSCHALPPAALLCTLGEAVAGSCCHALPARGILAFPKLVASVSESGLQAQCGMKFHCKLSGGISGHPHCCVHPWGPTGLATESGSRTKDVWTMTSATDLALGVAS---AQDAGVQAAPAAACKAVATSPSLEAPETLNLFPEVMLESGLRQASSPVRDVRWDAEGMTWEVYGASVDPEVLGIAIQKHLEMQFEQLQQAPASE---DSLSAEGRRGPLR----AVMQSLRRPSCCGCSGAAPE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60269-1", "uniprot_id": "GRIN2_HUMAN", "id": "O60269-1", "name": "G protein-regulated inducer of neurite outgrowth 2", "aln": "--MSSSRPEPGPWAPLSPRLQPLSQSSSSLLGEGREQRPELRKTASSTVWQAQLGEASTRPQAPEEEGNPPESMKPARASGPKARPSAGGHWWSSTVGNVSTMGGSDLCRLRAPSAAAMQRSHSDLVRSTQMRGHSGARKASLSCSALGSSPVHRAQLQPGGTSGQGGQAPAGLERDLAPEDETSNSAWMLGASQLSVPPLDLGDTTAHSSSAQAEPKAAEQLATTTCHALPPAALLCGMREVRAGGCCHALPATGILAFPKLVASVSESGLQAQHGVKIHCRLSGGLPGHSHCCAHLWGPAGLVPEPGSRTKDVWTMTSANDLAPAEASPLSAQDAGVQAAPVAACKAVATSPSLEAPAALHVFPEVTLGSSLEEVPSPVRDVRWDAEGMTWEVYGAAVDLEVLGVAIQKHLEMQFEQLQRAPASE---DSLSVEGRRGPLR----AVMQSLRRPSCCGCSGAAPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B386-1", "uniprot_id": "A0A8M2B386_DANRE", "id": "A0A8M2B386-1", "name": "", "aln": "MAEAGHTISFPPVGTIPSDPLVTADCCSSELKAEDVLRNSSSEAPTERLNHCQIDQHNASPHRIAETHVS-DSVCLHPMSHQNKHDCSGSLMVHKDLNDHSLLS---IQRSHSDSLQIFKDAAASPRYCEMGASFCQGREKDVCAQSFP-SLVCKQAMPLQQSNTVTTSIRAGSSGSSSPTQPAKHSFIQICEVIPESTCPKFEKPVCCNSHFHHGAVKDTFAAYCHPQPIPAPAQLIPHLVGMDESYKGQGQTGNLLALPRLISSVSETGLDGNR-LLRCCNMDCSWSGP----LRPVGAHQWVDEK--TTSDASTMTSQEDLR----------DVGVQVG----------QDSKELPQHVFPEVCLVQQKTSKSQKSPVREVKWDAEGMTWEVYGASVDPEELGLAIQKHLEIQIKETKGIAAKLSRQNTTTSQHSSGSIQKRKKGFLGSLRHPACCSGTTGAVD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . . .. ::..** * : . :: :. : :.* : .: *: * : : : :*. . :.: * :. : * :: * .: : :. . .. :: .:...:: * * : : * . : : :.:* : . .: ... : . . :.:*..: * . : .:**:*:*::****:**:.: : *.:. . .* : *. . * *.*. **** ** *.***.. . * * * : : .. ****:*:*************:** * **:*******:*::: : .*. :: : : *.:: ..: ***:*:**. : .* :", "identical_positions": 85, "similar_positions": 137, "identity": "18.2%" }, { "cls_id": "homologset.agr.MGI:2444563", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96LR4-1", "uniprot_id": "TAFA4_HUMAN", "id": "Q96LR4-1", "name": "Chemokine-like protein TAFA-4", "aln": "MRSPRMRVCAKSVLLSHWLFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCSSGNKVKTTKVTR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TPG5-1", "uniprot_id": "TAFA4_MOUSE", "id": "Q7TPG5-1", "name": "Chemokine-like protein TAFA-4", "aln": "-----MRVCAKWVLLSRWLVLTYVLMVCCKLMSASSQHLRGHAGHHLIKPGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEAAIVIEKWWCHMNPCLEGEDCKVLPDSSGWSCSSGNKVKTTKVTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5Y9S7-1", "uniprot_id": "A0A8I5Y9S7_RAT", "id": "A0A8I5Y9S7-1", "name": "", "aln": "-----MRVCTKWVLLSHWLVLAYMLMVCCKLMSASSQHLRGHAGHHVIKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEGDPVADTEVFDSEGHQDAELCCVDYQTSESSTSELPQEFVAAV--", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:* ****:**.*:*:********************** ** *********************************************. * :. . : :.* * * : * * *. : .: * ", "identical_positions": 90, "similar_positions": 17, "identity": "64.29%" }, { "cls_id": "homologset.agr.MGI:2444572", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K369-1", "uniprot_id": "A0A0G2K369_RAT", "id": "A0A0G2K369-1", "name": "", "aln": "------MQKVLQTDDITN-----------NQVLRKRKRKRTETANSENANSASDKAQRDPYSGNAFLPGESSSDEETPLVELSKEELCN--KIESLKEKLRSIRKENSRLRQSLVMLQVLPQAVTQFEELVGMAETLLKSGGAMSTPASTLWRATNNSS-PDSFASLCS------NSNSTSSSPSSLKAEEEQQPGEKQ----FTIERWQIARCNK-SKPQKFINDLMQVLYTNEYMATHSLTGAKSSTSRDKVVKPAMNQNEVQEIIGVTKQVFPSADDVSIRRMIGQKLNNCTK----KPSVSKAPTSQEISRS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFX2-1", "uniprot_id": "BEND6_MOUSE", "id": "Q6PFX2-1", "name": "BEN domain-containing protein 6", "aln": "------MQKILQTDDITD-----------NQVLRKRKRKRTETANSENANSALEKAQRDPYSGNAFLPGESSSDEETPLMELSKEELCN--KIESLKEKLRSIRKENSRLRQSLVMLQVLPQAVTQFEELVGMAETLLKSGGAVSTPASTLWRATNNSS-PDSFASLCS------NSNSTSSSPSSVKAEEEQHPGEKQ----FTIERWQIARCNK-SKPQKFINDLMQVLYTNEYMATHSLTGAKSSTSRDKVVKPAMNQNEVQEIIGVTKQVFPSADDVSIRRMIGQKLNNCTK----KPNASKAPNSQDGILK------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SZJ8-1", "uniprot_id": "BEND6_HUMAN", "id": "Q5SZJ8-1", "name": "BEN domain-containing protein 6", "aln": "------MQKIVQTDEITN-----------TQAFRKGKRKRTETMDSENANSDMDKGQRDPYSGNAFLPGESSSEDEEPLAELSKEELCA--KIKSLKEKLTNTRKENSRLRQSLVMLQVLPQAVTQFEELVGMAEALLKGGGTMSTSASTLWRATNNSS-PDSFASTCS------NSNSNSSSPVSLKPEEEHQTDEKQ----FQIEKWQIARCNK-SKPQKFINDLMQVLYTNEYMATHSLTGAKSSTSRDKAVKPAMNQNEVQEIIGVTKQLFPNTDDVSIRRMIGQKLNNCTK----KPNLSKNLNSQDIK--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q933-1", "uniprot_id": "A0A8M9Q933_DANRE", "id": "A0A8M9Q933-1", "name": "", "aln": "MRRKTKAQRILDYENEEDEEEEQKPDCYSNGAQKRRKMYLSKEKAEENSSSEAGLQKLDVKVNELDCSSADLYTDSPPTSETEEAHYLQSYSKKELIAMVLCMQREMEDMKEQLRCLTACGKLARNLETLIEKTQVWSNGNNGISPGTPVSQGTTQAPGEPEAVIADVGSLPAVVNGQWLNQGPGPQKPHEATQNAHRDGLYTEFITPELLERCNTGTTAQKLTNDLLRGLYERECLASHSISGVVYNKRGQ--PKPALPTEEVQAILRTVQYFFPGKTDAEIKGYIRQKLQNEAKRLRKKPSLSGQYDSRDLNLPSPRSHLDMTDRN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:::: :: : . . :: * :: .**:.* : * .: .. . :. * * .: . . :.* : ::* . :::.* * . : . ::* *: ::. :... :*. :.. :*: .. *::. : . *.: ...* . *..* : .:: * : ***. :..**: ***:: ** .* :*:**::*. .. : ***: :*** *: ..: .**. *..*: * ***:* :* **. * *:: ", "identical_positions": 58, "similar_positions": 110, "identity": "17.68%" }, { "cls_id": "homologset.agr.MGI:2444575", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E1U8D0-1", "uniprot_id": "MTCL2_MOUSE", "id": "E1U8D0-1", "name": "Microtubule cross-linking factor 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METPAGESSARGYGP--PPAPAPAAERKKS---HRAPSPARPKDVAGWSLAKGRRGTG-------PGSATACG--------TASSARPDKKGRAVAPGTRGTGPRVAGVR---TGVRAKGRPRPGTGPRP-----PPPPPSLTDSSSEVSDCASEEARQLGLELALSSDAESAAGG----------------PAGTRTGQPPQPAQSGQQPPRPPASPDEPSVAASSVGSSRLPLSASLAFSDLTEEMLDCGPGGLVRELEELRSENDYLKDEIEELRAEMLEMRDVYMEEDVYQLQELRQQLDQASKTCRILQYRLRKAERRSLRAAQTG---------QVDGELIRGLEQDVKVSKDISMRLHKELEVVEKKRMRLEEENEGLRQRLIETELAKQVLQTELD---RPREHSLKKRGTRSLGKTDKKPTAQ--EDSADLKCQLHFAKEESALMCKKLTKLAKENDSMKEELLKYRSLYGDLDAALSAEELADAPHSRETELKVHLKLVEEEANLLSRRIVELEVENRGLRAEMDDMKDHGGG-GGPEARLAFSSLGG-ECGESLAELRRHLQFVEEEAELLR-----RSSAELEDQNKLLLNELAKYRSEHELDVTLSEDSCS----------------------------VLSEPSQEELAAAKLQIGELSGKVKKLQYENRVLLS-NLQRCDLASCQ-STRPMLETDAEAGDSAQCVP------APLG----ETLEPHAARLCRAR--------EAEALPGLREQAALVSKAIDVLVADANGFSVGLRLCLDNECADLRLHEAPDNSEGPRDAKLIHAILV-RLSVLQQELNAFTRKADVALGSSGKEQPEPFPALPALGSQGPAKEIMLS-----KDLGSDFQPPDFRDLLEWEPRIREAFRTGDLESKPDPSRNFRP-YRAEDNDSYASEIKDLQLVLAEAHDSLRGLQEQLSQERQLR----------------KEEADSFNQKMVQLKEDQQRALLRREFELQSLS----LQRRLEQKFWSQEKNILVQESQQFKHNFLLLFMKLRWFLKRWRQGKVLPSEEDDFLEVNSMKELYLLMEEEEMNAQHSDNKACTGESWTQN---------------TPNECIKTLADMKVTLKELCWLLQDERRGLTELQQQFAKAKATWETERAELKGHASQMELKAGKG---ASERP---GPDWKAALQR----EREEQQHLLAESYSAVMELTRQLQLSERHWS------QEKLQLVERLQGEKQQVEQQVKELQNR--LSQLQKAAEPWVLKHSDMEKQDNSWKEARSEKTHDKEGVSEAELGGTGLKRTKSVSSMSEFESLLDCSPYLAGGDARNKKLPNGPAFAFVSTEPVEPEKDAKEKAGLSTRDCSHIGSLACQEPAGRQMQRSYTAPDKTGIRVYYSPPVARRLGVPVVHD------KEGKILIEPGFLFTTAKPKESAEADGLAESSYSRWLCNFSRQRLDGGSGASTSGSGPAFP-ALHDFEMSGNMSDDMKEITNCVRQAMRSGSLERKV-KNTSSQTVGVATVGTQTIRTVSVGLQTDPPRS---SLHSKSWSPR-SSSLVSVR-SKQISSSLDKVHSRIERPCCSPKYGSPKLQRR---SVSKLD----STKDRSLWNLHQ--GKQNGSAWARSTTTRDSPVLRNINDG---LSSLFSVVEHSGSTESVWKLGMSEARTKPEPP---------------KYGIVQEFFRNVCGRAPSPTTAAGEESCKKPEP-----LSPASYHQPEGVSRILNKKAAKAGGSEEVRPTMLSQVGKDGILRDGDGSLILPSEDAVCDCSAQSLASC------FIRPSRNTIRHSPSKCRLHPSESGWGGEERAAPQ-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZZ05-1", "uniprot_id": "A0A8I5ZZ05_RAT", "id": "A0A8I5ZZ05-1", "name": "", "aln": "MDAGSGPLRSAGPLPGNILSCRPRGPHGDAGLLGSWAGCDPPARSGAIGVPERREQAEAAAAQARLTLEGVAVASRIPPSLPARVPPRCSRRVRLLFAEPRAPEPRQRGGELAGLRGGRAAPGGAGALASAGLGVRGGDRRAGCSRGPGALRGRGEAEGAGTGRSRSRSRGAWRRSGRALRAPSGGEAARRGAGPERSPRTQETGAQSRPERRECIREPPQGHPGRPLQGHARRSLRPGEAAMEAPAGESSARGYGP--PPAPAPAAERKKS---HRAPSPARPKDVAGWSLAKGRRGTG-------PGAATACG--------TASSARPDKKGRAVAPGARGAGPRVAGVR---TGVRAKGRPRPGTGPRP-----PPPPPSLTDSSSEVSDCASEEARLLGLELALSSDAESAAGG----------------PAGTRTGQPPQPAPSGQQPPRPPASPDEPSVAASSVGSSRLPLSASLAFSDLTEEMLDCGTGSLMRELEELRSENDYLKDEIEELRAEMLEMRDVYMEEDVYQLQELRQQLDQASKTCRILQYRLRKAERRSLRAAQTG---------QVDGELIRGLEQDVKVSKDISMRLHKELEVVEKKRMRLEEENEGLRQRLIETELAKQVLQTELD---RPREHSLKKRGTRSLGKTDKKPTAQ--EDSADLKCQLHFAKEESALMCKKLTKLAKENDSMKEELLKYRSLYGDLDAALSAEELADAPHSRETELKVHLKLVEEEANLLSRRIVELEVENRGLRAEMDDMKDHGGG-GGPEARLSFSSLGG-ECGESLAELRRHLQFVEEEAELLR-----RSSAELEDQNKLLLNELAKYRSEHELDVTLSEDSCS----------------------------VLSEPSQEELAAAKLQIGELSGKVKKLQYENRVLLS-NLQRCDLASCQ-STRPMLETDAEAGDSAQCVP------APLG----ETLEPHAGRLCRAR--------EAEALPGLREQAALVSKAIDVLVADANGFSVGLRLCLDNECADLRLHEAPDNSEGPRDAKLIHAILV-RLSVLQQELNAFTRKADVALGSSGKEQPEPFPALPALGSQGPAKEIMLS-----KDLGSDFQPPDFRDLLEWEPRIREAFRAGDLESKPDPSRNFRP-YRAEDNDSYASEIKELQLVLAEAHDSLRGLQEQLSQERQLR----------------KEEADSFNQKMVQLKEDQQRALLRREFELQSLS----LQRRLEQKFWSQEKNILVQESQQFKHNFLLLFMKLRWFLKRWRQGKVLPSEEDDFLEVNSMKELYLLMEEEEMNAQHTDNKACTGDSWTQN---------------TPNEYIKTLADMKVTLKELCWLLRDERRGLTELQQQFAKAKATWETERAELKGHASQMELKAGKG---ASERP---GPDWKAALQR----EREEQQHLLAESYSAVMELTRQLQMSERHWS------QEKLQLVERLQGEKQQVEQQVKELQNR--LSQLQKAAEPWVLKHSDLEKQDNSWKEARSEKTHDKEGVSEAELGGTGLKRTKSVSSMSEFESLLDCSPYLAGGDARNKKLPSSPAFAFVSAEPIEPEKDAKEKPVLPARDCSHMGSLACQEPAGRQMQRSYTAPDKTGIRVYYSPPVARRLGVPVVHD------KEGKILIEPGFLFTTAKPKESAEADRLAESSYSRWLCNFSRQRLDGGSGASTSGSGPAFPTALHDFEMSGNMSDDMKEITNCVRQAMRSGSLERKV-KSTSSQTVGLATVGTQTIRTVSVGLQTDPPRS---SLHSKSWSPR-SSSLVSVR-SKQISSSLDKVHSRIERPCCSPKYGSPKLQRR---SVSKLD----STKDRSLWNLHQ--GKQNGSAWARSTTTRDSPVLRNINDG---LSSLFSVVEHSGSTESVWKLGMSEARTKPEPP---------------KYGIVQEFFRNVCGRAPSPTTAAGEESSKKPEP-----LSPASYHQPEGVARILNKKAAKAGGSEEVRPTMLSQVGKDGALRDGDGSLILPSEDAVCDCSAQSLASC------FIRPSRNTIRHSPSKCRLHPSESSWGGEERAAPQ-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94964-2", "uniprot_id": "MTCL2_HUMAN", "id": "O94964-2", "name": "Microtubule cross-linking factor 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAPAAEPPVRGCGPQPAPAPAPAPERKKS---HRAPSPARPKDVAGWSLAKGRRGPG-------PGSAVACS--------AAFSSRPDKKGRAVAPGARGAGVRVAGVR---TGVRAKGRPRSGAGPRP-----PPPPPSLTDSSSEVSDCASEEARLLGLELALSSDAESAAGG----------------PAGVRTGQPAQPAPSAQQPPRPPASPDEPSVAASSVGSSRLPLSASLAFSDLTEEMLDCGPSGLVRELEELRSENDYLKDEIEELRAEMLEMRDVYMEEDVYQLQELRQQLDQASKTCRILQYRLRKAERRSLRAAQTG---------QVDGELIRGLEQDVKVSKDISMRLHKELEVVEKKRARLEEENEELRQRLIETELAKQVLQTELE---RPREHSLKKRGTRSLGKADKKTLVQ--EDSADLKCQLHFAKEESALMCKKLTKLAKENDSMKEELLKYRSLYGDLDSALSAEELADAPHSRETELKVHLKLVEEEANLLSRRIVELEVENRGLRAEMDDMKDHGGGCGGPEARLAFSALGGGECGESLAELRRHLQFVEEEAELLR-----RSSAELEDQNKLLLNELAKFRSEHELDVALSEDSCS----------------------------VLSEPSQEELAAAKLQIGELSGKVKKLQYENRVLLS-NLQRCDLASCQ-STRPMLETDAEAGDSAQCVP------APLG----ETHESHAVRLCRAR--------EAEVLPGLREQAALVSKAIDVLVADANGFTAGLRLCLDNECADFRLHEAPDNSEGPRDTKLIHAILV-RLSVLQQELNAFTRKADAVLGCSVKEQQESFSSLPPLGSQGLSKEILLA-----KDLGSDFQPPDFRDLPEWEPRIREAFRTGDLDSKPDPSRSFRP-YRAEDNDSYASEIKELQLVLAEAHDSLRGLQEQLSQERQLR----------------KEEADNFNQKMVQLKEDQQRALLRREFELQSLS----LQRRLEQKFWSQEKNMLVQESQQFKHNFLLLFMKLRWFLKRWRQGKVLPSEGDDFLEVNSMKELYLLMEEEEINAQHSDNKACTGDSWTQN---------------TPNEYIKTLADMKVTLKELCWLLRDERRGLTELQQQFAKAKATWETERAELKGHTSQMELKTGKG---AGERA---GPDWKAALQR----EREEQQHLLAESYSAVMELTRQLQISERNWS------QEKLQLVERLQGEKQQVEQQVKELQNR--LSQLQKAADPWVLKHSELEKQDNSWKETRSEKIHDKEAVSEVELGGNGLKRTKSVSSMSEFESLLDCSPYLAGGDARGKKLPNNPAFGFVSSEPGDPEKDTKEKPGLSSRDCNHLGALACQDPPGRQMQRSYTAPDKTGIRVYYSPPVARRLGVPVVHD------KEGKIIIEPGFLFTTAKPKESAEADGLAESSYGRWLCNFSRQRLDGGSAGSPSAAGPGFPAALHDFEMSGNMSDDMKEITNCVRQAMRSGSLERKV-KSTSSQTVGLASVGTQTIRTVSVGLQTDPPRS---SLHGKAWSPR-SSSLVSVR-SKQISSSLDKVHSRIERPCCSPKYGSPKLQRR---SVSKLD----SSKDRSLWNLHQ--GKQNGSAWARSTTTRDSPVLRNINDG---LSSLFSVVEHSGSTESVWKLGMSETRAKPEPP---------------KYGIVQEFFRNVCGRAPSPTSSAGEEGTKKPEP-----LSPASYHQPEGVARILNKKAAKLGSSEEVRLTMLPQVGKDGVLRDGDGAVVLPNEDAVCDCSTQSLTSC------FARSSRSAIRHSPSKCRLHPSESSWGGEERALPPSE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B8S3-1", "uniprot_id": "A0A8M2B8S3_DANRE", "id": "A0A8M2B8S3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKTKVDTGSPTHFVSSKEKRQKQKMESSTGELEQPQPQHQPTQQPP--PAPPLQVTEKKKI---HRAPSPARPKDVAGWSLTKIRGGIGTPTLSVKPGAIYLGGRVSRRSPVTGKDAKTEKNKPTGKPALSATGAQKSSVKSNKSGRRKVSDASIGSDDLSKDSGCAPGKLSPTDSSSELSDCASEENKVS--TDALSSDTETSSRGGIDGDKAAAEHGLLDKSGHTKTSAEKERLSLGMETAEGSVSPGEERSLTS--MDSRMPASTSLAFSDLTEELMDGMNEELVREIEELRSENDYLKDEMEELRSEMLEMRDMYLEEDVYQLQELRQQLDQANKTCRILQYRLKKAERRSIRVAQTG---------QVDGELIRTLEQDVKVAKDVSIRLHNELDTVEKKRSRLEQENEELRVKLQDLEVAKQVLQAEME---KARENSLKKRSARPNNKPDKKASPQPPEDSSDLKCQLHFAKEESALMCKKLTKMVKDNESMREELAKFRSMYGEVDASLTVEEVADSPHTREAEVKVHLKLVEEEANLLSRRIVELEVENRGLRAEMDDMKIQDSP-GGIGITGGVGSHLLFSTSENVMELQRHLQFVEEEADLLR-----RSLIEMEEQNKLLMNELNHYKSELPAVTEIEPSSSSTT-------------ITSPTILPGPSEDALNEATHKELLAARLQIAELNGKVKKLQYENRVLLS-NLQRCDLASNQGSARPSLETDAEAGDSAECIPSHTHREGPVGDEQTDILEEKNLKVSRTSHTHTSQCLSVKDLLAIRDQAQLVTSAIQLLTSPDTSCISPDSVYRKITANDSAEPVLLEKSQTPSSTLPVVEVLHGRLQFLQAQLQALSERVDALDEPAVRDCFDGMSQMPLLSEAEDPTANCLCPADAQFNLNTAQQKPDSRDQPDCEVKVHLCKADEESNCHKDSNKDEESDLKDTNSDLLTEQVHELHALLSEAREKAHGAQEALSQERLER----------------HSDIH----KLSQLQEEHQKALLRRDFQLQSLS----LQTRLQQKLWSQERNLLVQESQQLKESLLLISLKLRWLLKQWRLGKKLDTESKDILEVNSVKDLRILLEED-LSSHYGDNKMSAAEEPQLNPTPKEHNLPEKSISQQPSGFGSTLSDLKVALQDLSGELREERQSSQELTQQFARAKASWEVERMELKSIITQLEGKLGKASVAVGEKD---FSDLKEALKK----EREEHQHLLADSYAAVMDLTKQLQISEKNWS------RERRELLEHFNQERSQWDQRVRDAQSKGAQSLHDKTSEKEALADVVAGSSAMQRTKSISTLTELKSLLDTSLLLHSHKVIGEPEYAMAQHQSAAPAS-ILARTDLSD---LNNKNWKYLTSDSAILEKGDQFKT-WDCPSTNSNSSFPGLELNKEYIQRSYTAPDKTGIRIYYSPPTVRRMERRPVKENTQQDYQQGLSSRDAAMIDPSGQIAASAPLLTTSPSAYEQWLSSLSQQHRDLLEGRTGGSAP------FHGLEISGNLSDDMKEMTNCVRQAIRSSSLERKCSKDTGSQTVGVCSTGTQTAQFVSIGMQTDVPISTARGLQGKAWSPRPSTSLASAR-SRQISSSLDKVHSRIDRPCCSPKYGSPKLTRRVSTSSSKLETSSTSSRDRSVWNLHNRTGSQNGSAWARSTTTRDSPVLSGLNDG---LTSLFSVVEHSGSVESLWKADTCPGRQAAGKPSCPSIGVGLGEAGAQKYGVVQEFLRNVCGRTTSVSIID----EPKPE------CMPGSLISTDNITKIVNKRFMKTQRDE------LVATGKDAMSSSSS-----TVEDSVCDCNSQTVTTC------FARHSRSTTRHTHGQCKHRVQESSMGNEERVNMINERE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PCE3-1", "uniprot_id": "M9PCE3_DROME", "id": "M9PCE3-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHHLYPSLKGDQLCPLGFHPQTRYPTRCKRCFRDYKEHGARRAGEEVAASSPNLSDAQSSRPSSRTWTSTQNLTSANATNGNDIVVHFNVELRKRPQSWASTPDIDEPDNVARRPPATASTSRAASSAEDQDVAVTVKLPVPPRRHTTALDIKEVEHAITPPTRVTSSPSKTSSIP---DELVILSTDSLAERVRKMNLLKKQRSLNSRENSRERSVPRREEESESTATPTPVVPDRPERSK----------------SGTSLNQLAQAEQKRAALPPKKVAVASTTTASSSNSSSTSLKTSNSTSASNEVKVVTSTSSSSTSSSSVRRKEADSVASKEIKRQTVPAASISHSNSTSSTASTASKSQDTNGMQEQMKALKLELETMKTRAEKAEREKSDILLRRLASMDTASNRTAASEALNLQQKLNEMKEQLDRVTEDKRKLNLRMKELENKGSESELRRKLQAAEQICEELMEENQSAKKEILNLQAEMDEVQDTFRDDEVKAKTSLQKDLEKATKNCRILSFKLKKSDRKIETLEQERQSSFNAELSNKIKKLEEELRFSNELTRKLQAEAEELRNPGKKKAPMLGVLGKSTSADAKFTRESLTR-GGSQEDPQHLQRELQDSIERETDLKDQLKFAEEELQRLRDRERKRVRFSCGTQTEVPLEVVAFPRGTQTVATVQSDMSTSVENLVTSNVAVTQTDFEVPDRNVSIERETMSSPFAGLFPPSSSSRVGQSGSLLFPSAISHVLLSGAGRKLSPTPHPHRLAPEVHADRDEGISDEDDPAELRILLELNEQEASILRLKVEDLEKENAESKKYVRELQAKLRQDSSNGSKSSLLSLGTSSSAAEKKVKTLNEELVQLRRTLTEKEQTVDSLKNQLSKLDTLETENDKLAKENKRLLALRKASEKTGEVDQKMKESLAQAQRERDELTARLKR---MQLEAEDKLPPRTAKRVNDLTPKSHLKKWVEELEDEISEMRVMLSSSGTDQLKALQSAKGALEEDLRKCKQKLSLAEGDVQRLKLLNGSSSKVSELEQKLKRGDEEAKKLNSKLKDLEDKVKKQEAQLKLGETSKSTWESQSKREKEKLSSLEKDMEKQAKEKEKLEAKISQLDAELLSAKKSAEKSKSSLEKEIKDLKTKASKSDSKQVQDLKKQVEEVQASLSAEQKRY--------------EDLNNHWEKLSEETILMRAQLTTEKQSLQAELNASKQKIAEMDTIRIERTDMARKLSEAQKRIADLQAKALKTVNGNGAEYERTVLKNKLAEKEHEYERLRRENEMNIDLVFQLRKDNDDLNGKLSDYNRIEQAQSSLNGHGARREAEIRELKEQLQSTELQMKSEVATVRLRYEQQVKNLSGELTSMQRQCERFKKDRDAFKQMLEVAQKKIGDLKANNTGRQSRGSMHSSDDDDKSKIAYLEQQIGHLEDQLVESRLESSKIKTELVSERSANEIKISEMQSKLNEFEEERVIGSGSTKLPGMKTKLELSWQKERE----DQQRLLQETSTLARDLRQTLFEVERERDKERLESKRKLDQIKRATEEEMEEGRKKIAELQCDLLELRDVHAKLRTSNEKLRRERERYEKELIKRRMEADGGDRKVGALLQTVDELVKIAPDLKIVGSGGSARSSSSSGYDKNLRPEQPNVRRSRSPSPTLSSSQITSVLARLAEASEELRKFQRVNEDEQERSRMRRSNLRRAASQENDPHGSTSSVASAAGSQRGGGRLSRNSSNNGSLIRKSLSLDHSIQRDQNIWRQDDGSVSSMQSIDSELG-------GLVRDSSLDSRLDSRLSGGSTQSDIPRGPRKKKKGIMGKLRSLTKSSRNSESEISIQGSDSDISVASDMRSSKKDLRGRLSGMFKRSGSASRSESMERAGSDQRPVAVTVVGHPDGPQPREPPPANSLTPRPIRSIPKPPSAGAPTTPTTRRRVAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :*: :*. .*.:** . :. . . : :. . : :: : . .: : :.: . . . :.* * * ** : .. .. . . ... . .. :* .: : * * : *: .: : . . . :. :. ..*::. .: . ... . . *: : .: : *: .*.. : *: :. : .:* * .:. :: .::::*: * :.: :*: . : *. : : *: ::: :* .*:. *: .: :*. . * .*: *::: *: *: *..: * * : *. : : : . ::: : : : : .** * .:: * * .:. *: . : ** . * :*: :*:*.*** : ** * . *.:: :: : :. . . * * .:... : .: . .*.: . .:**** :: . :. * :.:* : * * : * :. . . : : : . : .. :. :.: .: . : . :. : . * . . * : : : .. . : . . . : : : : : : : . . : . : . . *. * :.::. : :.: : . ..: . *: :*::. :: : .: * * . * ::*: * *::: * .:: * . : :. . : : * : .:: :::: . : : :. : : : . . . . ..*:: .: :: ::. :. : :* : . ** :: :: : : .. . : .: : :: : *:*.. . * . ::*. **: .: . . .. : . :: . : : .::: :.: : : :: .: . : * . : . : . : :. * . . : :. .. . .: . ..: * * :: :: .: :.. : : . . :: . : :. :* . *: .. ::*: . ..:.** .: :: .:: . . . ...:. . .. ..* *:. *.:*.. : . : . : :* . .: . *. *: : :: *. .. * * .: .. : . .:. : . :*: . :.:*: . . .: ..: .:.* :.. * .* . . :: .. . . * .. ... . * : .* . ::: * . : : : . .. * ", "identical_positions": 124, "similar_positions": 544, "identity": "5.84%" }, { "cls_id": "homologset.agr.MGI:2444576", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AFD4-1", "uniprot_id": "A0A8I6AFD4_RAT", "id": "A0A8I6AFD4-1", "name": "", "aln": "-MESHLNQDGVPRPSYVFSADPIARPSEINFDGVKLDLSHEFSLVAANPGANSLESKNYLQVCLRIRPFTQSEK-GHEAEGCVQVLDSQTVLLKDP-QSILGHLSEKSSGQMAQKFSFSRVFGPETSQKEFFQGCIMQPVKDLLKGHSRLIFTYGLTNSGKTYTFQGTEENIGILPRTLNVLFDSLQERLYTKMSFKPHRCREYLQLSSDQEKEESANKNTLLRQIKEVTIHNDSYDILCGRLTNSLTIPEFEETMNNCEQSSLNVDN-IKYSVWVSFFEIYNESIYDLFVPVSSKLQKRKMLRLSQDVKGYSFIKDLQWIQVSDSKEAYRLLKLGVKHQSVAFTKLNNASSRSHSIFTIRILQIEDSEIPRVTRVSELSLCDLAGSERSMKTQSEGERLREAGNINTSLLTLGKCISVLKNSD-KSKIQQHVPFRESKLTHYFQSFFTGKGKICMIINISQCCSAYDETLNVLKFSTVAQKVYVPDTLSSSQEKSFGSTKSLQDVSLGSNLDNKILNVKRKTVS-WENSLEDVVENEDLVEDLEENEETQNMETELTDEDSDKPLEEGGVCAGHGKNKKLLDLIENLKKRLINEKKEKLTLEFKIREEVTQEFTQYWSQREADFKETLLHEREILEENAERRLAIFKDLVGKPGESQDEPASRFCTMELETEESHNYVGVEDIFDSLEDDVTDIKKQAELAHLYITS-LVDPQEAIACLQLKYNQVKAELAETKEELIKAQEELKNKE--SDSLVQALKTSS------------------------------------------KVDTS--LISNKSTGNETTEMPKKSRTQTHSERKRLNEDGLQLGEPPAKKGLILISPPITEDQDKREEMQQSVSEGAEEDSRVLQEKNEELKRLLTIGENELRNAKEEKAELNKQVVSLQQQLCFFEEKNSSLRAEVEQIQASYDLAAAELHTQRAVNQEQKDRILQLSGKMETAARRIESNVSQIKQMQTKIDELRSLDSPSHISKIDLLNLQDLSSGAN---LLNTSQQLPGSD-LPSTWVKEFHTQELSRESSFHSSIEAIWEECKEIVKASSKKSHQIQGLEELIEKLQVEVKNCRDENSELRAKESEDKNRDQQLKEKESLIQQLREELQETTVSLRVQVQLVAEREQALSELSRDVTCYKAKVKDLEVMVETQKEECKRLAELEQSILEKESAILKLEASLKELEAKHQDHIRSTTHLNAEEVKFREEITQLANNLHDTKQLLQSKEEENEISRQETEKLKEELAANSVLTQNLQADLQRKEEDCAELKEKFTDAKKQIEQVQREVSVMRDEEKSLRTKINELEKKKNQYSQEIDMKQRTIQQLKEQLSNQ-KMEEVVQQYEKVCKDLSVKEKLIEAMRLTLVEQEQTQAEQDRMLEAKSQEADWLAGELDTWKDKFKDLETRSNQKVTTEAMEDSDVLSEKFRKLQDELQESEEKHKADRKKWLEEKAVLTTQAKEAETLRNREMKKYAEDRERCLKLQNEVETLTAQLAEKTGELQKWREERDQLVTAVETQMQALLSSSKHKDEEIQQLRKAVAKSTGTVSGRVLENQTMNLKPECNDSVDLGGVETELQSTSFEISRNTAE------------------------------------DGSVVLDSCEVSTENVQSTRFPKPELEIQFTPLQPNKVAVKHPGCATPVTIKIPKARKRKSGEVEEDLVKCENKKNSTPRSNVKFPVSEHRNSSFKKEQKVFLCPSSKKTYSLRSQASTVGANVASKKKEGTLQKFGDFLQHSPTILQSKAKKIIETMSSPKLSTVEVSKENVSQPKKAKRKLYRNEISSPINISG-QVILMEQKAKETDHQILKRRLRTRTAK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80WE4-1", "uniprot_id": "KI20B_MOUSE", "id": "Q80WE4-1", "name": "Kinesin-like protein KIF20B", "aln": "-MESHLNPDGVPRPSYVFSADPIARPLEINFDGVKLDLSHEFSLVASNPAANSLGSKNYLQVCLRIRPFTQSEK-EHEAEGCVQVLDSQSVLLKDP-QSILGHLSEKSSGQVAQKFSFSKVFGPETSQKEFFLGCIMQPVKDLLEGHSRLIFTYGLTNSGKTYTFQGTEENIGILPRTLNVLFDSLQERLYTKMSFKPHRCREYLKLSSDQEKEESANKNTLLRQIKEVTIHNDSYDVLCGHLTNSLTIPEFEESVNSCDQSSLNVDN-IKYSVWVSFFEIYNESIYDLFVPVSSKFQKRKMLRLSQDIKGYSFIKDLQWVQVSDSKEAYRLLKLGVKHQSVAFTKLNNASSRSHSIFTIRILQIEDSEIPRVTRVSELSLCDLAGSERSMKTQNEGERLREAGNINTSLLTLGKCINVLKNSE-KSKVQ-HVPFRESKLTHYFQSFFTGKGKICMIINISQSCSAYDETLNVLKFSTTAQRVYVPDTLSSSQEKSFASNKSLQDVSLDSNLDNKILNVKRKTVS-WENSLEDVLENEDLVEDLEENEETQNMETELTDEDSDKSLEECRVSTCHKKNKELLDLIEKLNKRLINENKEKLTLELKIREEVTQEFTQYWSQREADFKETLLHEREILEENAERRLAIFKDLVGK-CDSQDEPTNRICDIELETEEAHNYVGVEDIFHSLQDDVTDIKKQAELAHLYITS-LVDPQEAIACLQLKFNQVKAELAETKEELIKAQEELKNRE--SNSLVQALKTSS------------------------------------------KVDTS--LTSNKSTCNETSEMPKNSRAQTHSERKRLNEDGLQLGEPPAKKGLILVSPPITEEQNKMGEMQQSVSEVVE-GNRVLKEKNEELKRLLTIGENELRNEKEEKAELNKQVVSLQQQLRFFEEKNSSLRADVEQIQASYNSAVAELQTQKAVNQEQRDRILKLSQEMETAARSIESNVSQIKQMQTKIDELRSLDSPSHISKIDLLNLQDLSSGAKGDNCLNTSQQLPGGD-FSSTWVKEYHTQEISRENSFHASIEAIWEECKEIVKASSKKSHQIQGLEEQIEKLQVEVKGYREENSDLRAQESQGKNRDHQLKEKESLIQQLREELQEKSVSLRVQVQLVAEREQALSELSQDVTCYKAKIKDLEVIVETQKDECKRLVELEQSILEKESAILKLEANLKECEAKHQDHIR-TNDLSAKEVKFREEVTRLANNLHDTKQLLQSKEEENEISRQETEKLKEELAANSILTQNLKADLQKKEEDCAELKEKFIDAKKQIEQVQREVSVMRDEEKLLRIKINELEKKKNQYSQDLDMKQRTIQQLKEQLSNQ-KMEEAVQQYEKVCKDLSVKEKLVEDMRLTLVEQEQTQAEQDRVLEAKSEEADWLATELDKWKEKFKDLETRSNQRLNTGTMDDLDVLTRKFSKLQDELQESEEKYKADRKKWLEEKAVLTTQAKEAENVRNREMRKYADDRERCLKLQNEVETLTAQLAEKNSELQKWREERDQLVTAVETQMKALLSSCKHKDEEIQELRKAAAKSTG------TENQTMNPKPEYNDSVDLGGVETEPQSTSLEISRNTAE------------------------------------DGSVVLDSCEVSTENVQSTRFPKPELEIQFTPLQPNKMAVKHPGCPTPVTIKIPKARKRKSGEVEEDLVKCENKKNSTPRSNVKFPVSEHRNSPVKKEQKVSVGPSSKKTYSLRSQASTVSANIASKKREGTLQKFGDFLQHSPTILQSKAKKIIETMSSPKLSTVEVSKENVSQPKKAKRKLYRNEISSPINISG-QVILMEQKVKETDHQILKRRLRTRTAK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96Q89-1", "uniprot_id": "KI20B_HUMAN", "id": "Q96Q89-1", "name": "Kinesin-like protein KIF20B", "aln": "-MESNFNQEGVPRPSYVFSADPIARPSEINFDGIKLDLSHEFSLVAPNTEANSFESKDYLQVCLRIRPFTQSEK-ELESEGCVHILDSQTVVLKEP-QCILGRLSEKSSGQMAQKFSFSKVFGPATTQKEFFQGCIMQPVKDLLKGQSRLIFTYGLTNSGKTYTFQGTEENIGILPRTLNVLFDSLQERLYTKMNLKPHRSREYLRLSSEQEKEEIASKSALLRQIKEVTVHNDSDDTLYGSLTNSLNISEFEESIKDYEQANLNMANSIKFSVWVSFFEIYNEYIYDLFVPVSSKFQKRKMLRLSQDVKGYSFIKDLQWIQVSDSKEAYRLLKLGIKHQSVAFTKLNNASSRSHSIFTVKILQIEDSEMSRVIRVSELSLCDLAGSERTMKTQNEGERLRETGNINTSLLTLGKCINVLKNSE-KSKFQQHVPFRESKLTHYFQSFFNGKGKICMIVNISQCYLAYDETLNVLKFSAIAQKVCVPDTLNSSQEKLFGPVKSSQDVSLDSNSNSKILNVKRATIS-WENSLEDLMEDEDLVEELENAEETQNVETKLLDEDLDKTLEENKAFISHEEKRKLLDLIEDLKKKLINEKKEKLTLEFKIREEVTQEFTQYWAQREADFKETLLQEREILEENAERRLAIFKDLVGK-CDTREEAAKDICATKVETEETHNYVGFEDIIDSLQDNVADIKKQAEIAHLYIAS-LPDPQEATACLELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKELINIIDQKEDTINEFQNLKSHMENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIED--IRVLQENNEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENN--RLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQ-KVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLG-KLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSK------IETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIE------------------------------------DGSVVLDSCEVSTENDQSTRFPKPELEIQFTPLQPNKMAVKHPGCTTPVTVKIPKARKRKSNEMEEDLVKCENKKNATPRTNLKFPISDDRNSSVKKEQKVAIRPSSKKTYSLRSQASIIGVNLATKKKEGTLQKFGDFLQHSPSILQSKAKKIIETMSSSKLSNVEASKENVSQPKRAKRKLYTSEISSPIDISG-QVILMDQKMKESDHQIIKRRLRTKTAK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GXF8-1", "uniprot_id": "A0AC58GXF8_DANRE", "id": "A0AC58GXF8-1", "name": "", "aln": "MMESCLNHK-------------PDRVDSITVEDLRKDLFSEFSKLSRDSVS---LEKEHLQVYLRVRPFTSTERAEGESQDCISIEPPDTVILKAPKASLTARHSERFGPQLAQRFQFSQVYGPETTQKEIFDGTTKSLVKEVLDGGNSLIFTYGVTNAGKTFTFLGPESDGGILPRSLNVIFNSIEGRIYLQNNIKPHRCVDFTRLTKEQQDEEATNKRNLLRRFKDNDSQK---TLSSMSSSSCSSFDSSTSSDMNGDSVYLDEDSHVKFSVWVSFCEIYNESIHDLLDFVPNGSHRRNALRLAQDVKSNSFVKDLKWVQVNSADEALKVVKIGRKNQSFSSTKLNNISSRSHSIFSIRMLRIEDVGVPRVQTISELSLCDLAGSERCARTQNRGERLKEAGNINTSLLTLGKCINALRLNQTQSKFHQHIPFRESKLTHYLQGYFCGRGKACMIININQCASVYDETLNVLKFSAVAQKVVVLNPKPAPS---IALKRSARDVSMIINNADKKDWTRRSSIMGWEMSLEDVQEDENDEDMDEEEVESDDESIVDR-TVLETVE-NQELCELQVK-------IEELQEKLIKEESEKLTLEARIREEVTTEFMELFSNMEKDYSERLQREKEIVEERAERRLEILKNLVNR-----TIEE---MTTDENAAKEAKMELLDTMIEAMRSDLTKIKGDAESVQLCLAN-VPESPGKLSHLRTELEEIKAELLKSQQQLSLKSKEFEESCIQMQDLNDQLLQAT----------------------------------------------------RNYENQKVRCQELMSICQEKDDMVSKLQTALEQNDEAASKDRALINNIREEILHFKNSCKCKLNEEHD--EMTS-QKNQQLQQELKMKDDQLNQLKLEHASLEKAMRDISDRLSELTQTHEATVAMERAEVNKVTNENKALANELDELQQRAN---EMSSKVETIQTELGNQSKKANELSEELHTARALIR---------EHQEESCSHSQTIESLMIEAAHLRLELSTCQLSRDRKEAECERMVALSQEKNRQISDLEQELKQTRESVCQLEELCSR---LKSERDAQAQEYQSLLNR-YEAQN-------LVVTQIRSNSDLLEELTALKHQHKKIEKQDDCWKTVQDNLIQTVSKLNQQEEILSIVQ-------------------------------------------TIVTNEIS-KARDEANMKITEMEKDLSNKNTELETKAQELMKVREHVNDGHNQIERMRCDLQQVEQERSDVRDQLCEANTQKEHLEKQILILSEESKMFQQRLCEAEKMKDQPRPCLSCIEQTIDPLQIEQSNHVLEKEDIQLFQTPCQES----KLIEETPVTLN-TEFKRTDEEELLKPRLTEIEFITEDLATLQEKNQNPR----------------------------VGVSDHSQQED------------GRAQRPEEHTRQQLVKKQD-------------------------------------TILKLQKDSVVSPNSDTQEADKLKQTSN---------------------------MKTKNEGDSVSPTQEQVAEQ--------------------------------------------DSSVLSTKSLREERFPKPELEISFTPLKPHRMNVRKPGEEESVTIKLRRTARKRKSTEIENSVESENCKNRRLKVNNRANMQSVETPTVQ-------GKKMSQLK--QKDSPAS----LKGKKDGPLQKIGDFIQSSPTLFGSKAKKIMSMVNVKSPEP-LNASENN-KPKRSKRKLFKTQVSSPMDIPSYPIIGSSDDDKESDHLIIKRKLRTRTAKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1RFH9-1", "uniprot_id": "A0A8M1RFH9_DANRE", "id": "A0A8M1RFH9-1", "name": "", "aln": "MMESGLKDD-------------PARPAILVVEDLRRNLSTEFDCSDLQDSS---DLKEHLKVYLRIRPFSAVEIENGESQDCVTIQRPDTVLLKPPQTSLSARLSDKSVPVTAQRFQFSQVYGPDTTQKDIFDGTVNGLVRNVLEGQNSLVFTYGVTNAGKTFTFLGPDTNPGILPRSLNMIFSSLEGRIFTQMCLKPQRCRDFIRLTKEQQNEEAASKRNLLKLFKESDAQR---NISGHCSKS-DIEDGSMLSDVNSAVLDVEMDMHTRFSIWVSFCEIYNENIHDLLEQHASNASRKTNLRLCQDVKGNSFIKDLKWVQVSSAEEALKVMKLGKRNQSISSTKLNLLSSRSHSIFSVRILKVEDVGIPRVESVSELALCDLAGSERCAKTQNKGERLKEAGNINTSLLSLGKCINALRNNQ---QARQHVPFRESKLTHYLQGYFTGRGSACMIVNINQCSSMYDETLNVLKFSAVAQKVVVLTTKNIP----VGVKRSAREVSFIINNADCR-EMRRSSLVRWDPSLEDVQEDSDTEDEYEDQSEIEDTILNSEDECTETVQINKKLYEGQQRL------IVNTQQQLTAVQAELLTLEARVRDEVTKEFSELISQMQEDYSERMSRERELVEERCERRLEILKNLVEK-----TAMEDDRMNSTVAKSEEEKRVSLDSLFDSMSGDLAGIRNDAQAAQSCLVTSDPRVSATLHDLEKKVTELSEQLSISQNQLLLKTKELET----QSRLSDELEEVR----------------------------------------------------KTLESHREREFNLSDMCRQKDEMIAKLQATLDQHVERKAEDRAQMDSVQKKVIQCCCTIKEPLSSRNE--TRKRRQEGEGLEGQPPLKKGPPEDLKMPEDEADDGREDS--ALLEVKGQLECCLAEAKQKDKQITDLEQECHRLQVCIQDQKS---NLDERVSQEHILKEDVCQTTLE-SKQMATAVDFSN---------LNVAVASRCSNTTGAFAAKSLMAKRDLELREK--NKHILTLEKEIALMRQKAEHTSDYENLKKLNSELQAEVKSLCKVKAELKEKITCLQKEKEGLEDKEVGLTN-------PNTLGFKSKERDNQTHLMLSGKEAEIALRENALTLKETQLSALQKSLKQTQERLEEEE-------------------------------------------MQAVQEARRKEVERRREILAVAEEAIAQKDAELQKRQEEISRLKEEIKTSECKMSSLTVDLRRREDDSSDLREKLCDSKKQIQQVQKEISSMREAEKSLRLKLSDLEKTKVQLQNEIANRDRTINQLKAERSSGSKSDENLLLYQKACKDLQERERVIEDMRLALTEQEETQTQLDLELDNRNARIDELTQELASLREMLPEERDRSDSRPIS---KDVLQARQQITQAHESLQLANEKQQAERKKWMEEKLILIGQAKEAEERRNQDMRRFADDRERHVRQQAEMESLAARLNAREEEMERWRKERDTLVSALEVQLKKLIMSNGEKDQQIKMLQSSNTAQTPEEVSEDSRTEALQAELAVKEAEIQKLKEQLSLSATNSSIRRNSTTQTMEVEFSDMKPLNSSTIKHKSRTRGSVISQNSSGSGPLVLDSSEISTETGRRSRFPRPELEISFSPLQPDRFALKRQGEESAVTVKISRPTRKRKSGEMDKRKGARSSAVKKKAFSEPNPQDAVEGENIRNTR----CRLTPHLTPHREESPNSQESNQRGKKDKTLQKIGDFLQSSPTFLGSKAKRIMGLMSGKSPDGGSTPSLKL-KSKRDKRKYDRPDISSPMDIPAHRIIGRNPEDKESGNLIKKR-LRTRMAK-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** :: . * : .:.:: :* **. : : *::*:* **:***: * *::.*: : .::*:** * .: .: *:: **:*.**:*:** *:**::* * *:::*.* . *:****:**:***:** *.: : *****:**::*.*:: *:: : :**:*. :: :*:.:*:.** :.* **: :*: :. .. : . :: ::*:**** ***** *:**: .. ::. ***.**:*. **:***:*:**..:.** :::*:* ::**.: **** ********::::*::** :.** :***:********* :**..****:*:********:*****..*: .: : : *:**********:*.:* *:*. ***:**.*. ***********: **:* * . . .. :* ::**: * . :* :: *: ****: *:.: : *: * :: :. : : . * . :::* : * **** ::*:*** ** : :: : *:.* : :*:*::**..**** *:*:** : : : .: ::.:: .::: *: :*: .: :.. *. : ::. :* :: :* :*:: . * : * .. :. . : .: : *: :. :. : . : : . : ::.: *. .. .: * . . :. * . . *:: . ::. .:. . . :: : : . :: . : : : .: :: . .: :: * . : ::: * . *: : .* . : * : .. : * : : . . . : .::: : :. : . : : . : :. : *: * : :* :::*.: . . : **:: *:: ::::::: :::.* ::::::: : : .* :: :: : ** * * : ::**: *: : .. .* : :: *:: :::* ::* * .:.: : *. : . : :: :* . :: : . : ::.. : : :*:..* .::: : : : :: * . :: . ..:: : : : *.: . . **. :**:. : ***:*****.*:**:*.:. ::: * .**:*: :. :::.. :. ... . . . .: : :.::. *:: .***:***:* **::: ****:*: :. . . .. : :.*: *** ::***::*.. :* . . **:.: * ** ***: ** ", "identical_positions": 332, "similar_positions": 521, "identity": "17.69%" }, { "cls_id": "homologset.agr.MGI:2444579", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTG3-1", "uniprot_id": "D3ZTG3_RAT", "id": "D3ZTG3-1", "name": "", "aln": "MARLCRRVSCALLLGLAAVLLKARLVPAAARAELSRSDLSLIQQQQQQQQQ----EQRQREEAEEERMEVAGASFTLVVPVSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKTNSTVTRSNGAVLIKVPYRLGLSLTIIAYKDGYVLTPLPWKTGRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLTDAKSQPSVQFSKASIKLPDNHHISNVTGYLTVLQQFLKGDNFLSAIGITYST-GFENVELTPHAAICVKIYSGGKELNVAGPIHISLPLLHTSNVNVGDRIPAWTFNMKIGAWVHHDWGTVKEHNGHLIWTYDAPHLGYWIAAPSPSTLDLGINEDFPNVIGYHTAFLTAILGGTIVIIIVCLAALLCYCREKYGTPQKRERNITKLEILKRDQTTSTTHINHISSVKVALKAEDKPQLFNAKTSSYSPQKKETTKTETEERIPMVKTRDNFKIYNEDVSFLSVNHNNYSRNPTQSLEPSIGSKQPKHMNNNLSPSLGDAQEEKRYLTGNDEVYGRSHLPEQLMHIYSQPIAILQTSDLFSMPDQLHAAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPMHSHTQDPDAREEDIVLEGQQSLPSQTSDWSRYSNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNEHQLSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILDGGGGVIIEHPREESPGSKSTVEDFEANVSPTKKRGRPLPLAKRDSKTNIWKKREERPLIPIN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14CH0-1", "uniprot_id": "F171B_MOUSE", "id": "Q14CH0-1", "name": "Protein FAM171B", "aln": "MARLCRRVPCALLLGLAAVLLKARLVPAAARAELSRSDLSLIQQQQQQQQQQQLQEQKQREEAEEGRPEVPGASSTLVAPVSVFMLKVQVNDIVSRQYLSQAVVEVFVNYSKTNSTVTRSNGAVLIKVPYQLGLSLTIVAYKDGYVLTSLPWKTGRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLADAKSQPSVQFSKAFIKLPDNHHISNVTGYLTVLHQFLKVDSFLPATGVTYKS-GLENVELTPHAAICVKIYSGGKELKVDGSIHVSLPLLHTSNIKIGDRIPAWTFDMNAGVWVHHGWGTVKEHNSHLIWTYDAPHLGYWIAAPSPATLDFGINDDFQDITAYHTVFLTAILGGTIVIIIGFFAILLCYCRGKCATPQKRERNITKLEILKRDQTTSTTHINHISSVKTALKAEDKPQLFNAKTSSYSPQRKETTKTEAEERISMVKTRDNFKIYNEDVSFLSVNHN-YSRNPTQSLEPSMGSKQPKHINNNLSPSLGDAQEEKRYLTGTEEVYGRSHIPEQLMHIYSQPIAILQTSDLFSMPEQLHAAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPMHSHVQAPDAREEDIVLEGQQSLPSQTSDWSRYSNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKP-PHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNEHQSSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILEGGSGVIIEHPGEESPGRKSTVEDFEANTSPTKKRGRPPPLAKRDSKTNIWKKREERPLIPLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P995-1", "uniprot_id": "F171B_HUMAN", "id": "Q6P995-1", "name": "Protein FAM171B", "aln": "MARLCRRVPCTLLLGLAVVLLKARLVPAAARAELSRSDLSLIQQQQQQQQQQQ-QQQKQLEEAEEERTEVPGATSTLTVPVSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKTNSTVTKSNGAVLIKVPYKLGLSLTIIAYKDGYVLTPLPWKTRRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLADAKSQPSVQFSKALIKLPDNHHISNVTGYLTVLQQFLKVDNFLHTTGITLNKPGFENIELTPLAAICVKIYSGGKELKVNGSIQVSLPLLRLNDISAGDRIPAWTFDMNTGAWVNHGRGMVKEHNNHLIWTYDAPHLGYWIAAPLPGTRGSGINEDSKDITAYHTVFLTAILGGTIVIVIGFFAVLLCYCRDKCGTPQKRERNITKLEVLKRDQTTSTTHINHISTVKVALKAEDKSQLFNAKNSSYSPQKKEPSKAETEERVSMVKTRDDFKIYNEDVSFLSVNQNNYSRNPTQSLEPNVGSKQPKHINNNLSSSLGDAQDEKRYLTGNEEAYGRSHIPEQLMHIYSQPIAILQTSDLFSTPEQLHTAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPIHSHAQPPDAREEDIILEGQQSLPSQASDWSRYSSSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNELHSSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILDGGSGVIMEHPGEESPGRKSTVEDFEANTSPTKRRGRP-PLAKRDSKTNIWKKREERPLIPIN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********.*:******.********************************* :*:* ***** * **.**: **..**************:****************:*******:***********:*******:*********.***** *********************************:************* *******************:**** *.** : *:* .. *:**:**** **************:* *.*::*****: .::. *********:*: *.**:*. * *****.****************** *.* . ***:* :: .***.************:* :* ****** * .*************:****************:**.*******.******.******:**.:*:*:***:.******:**************:* ***********.:*******:*****.******:*******.:*.*****:********************** *:***:**********************************:***.* ********:**********:*******.***************************************** ********************************************** : ************************************************:**.***:*** ***** **********.****:**** **********************:*", "identical_positions": 700, "similar_positions": 86, "identity": "84.54%" }, { "cls_id": "homologset.agr.MGI:2444580", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LWX9-1", "uniprot_id": "F1LWX9_RAT", "id": "F1LWX9-1", "name": "", "aln": "----------------------MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPRGVGWRILKVLLWLLAILIGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNTVLLMDGNMGAYLITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKKGNVRIILFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPHTNKTYVEGDMFLHSRFTGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKNEQGMENQDKTYTRMKRKSPSEHSKDMGITRESTQVSVEDPLNDPPLVCIRSDFNEIVYKSSHLTSENLSLHLKESTSAAEADQDPAASPSLRTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH18-1", "uniprot_id": "TM117_MOUSE", "id": "Q8BH18-1", "name": "Transmembrane protein 117", "aln": "----------------------MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPRGVGWRILKVLLWLLAILIGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNTILLMDGNMGAYLITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKKGNVRIILFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPQTNKTYVEGDMFLHSRFIGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKNEQGMENQDKTYTRMKRKSPSEHSKDMGITRENTQVSVEDPLNDPALVCIRSDFNEIVYKSSHLTSENLSLHLKESTSEVEAEQEPAASQRMRTN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0C3-1", "uniprot_id": "TM117_HUMAN", "id": "Q9H0C3-1", "name": "Transmembrane protein 117", "aln": "----------------------MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPRGVGWRILKVLLWLLAILTGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNTILLMDGNMGAYIITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKSSHLTSENLSSQLNESTSATEADQDPTTSKSTPTN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7ZVW1-1", "uniprot_id": "TM117_DANRE", "id": "Q7ZVW1-1", "name": "Transmembrane protein 117", "aln": "MSSQSLHDCLRGRCLGVLRRMEIIGRFRYYFQHPWSRLLVSYLVTFFNFLIFAEDPVSHSQKEAHMSVVGNCFSFIISKYPAGF-WSVLKVLLWVLAIICGLIAGKFIFHRRLFGRVLRLKMFREDHGSWMTMFFSTILSLFIFSHIYNLLLLMSVRMRPYMVTEYMGIRNESFMKMAAVGTWMGDFVTAWMVTDMMLQDTHYPDWGRTARHLWRQGHNRIVLFWTVLICLTSVVVLVISTDWIRWDNLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDLDMNLPGLSTTQLKIRLPVCKRIFKEEYHIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPYEYGQYVGPGEKIYTVEDPDTLQDFNRSMLTWEWRSTNIDPRTNQTFNQSNAI--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***********::*:*** ****************.**:: ********: .*** *. * :******:***: *******:**:****::********************** ********* :***. .* .*::*:***********:***********************. *****::** :*::*: ** ******: *********:**** **:****************************************:*:***** *.::::::*. ::******:********************************:*****:***:*****:*.::*:*:**: *:*****.: :*:**:*: :.: : ", "identical_positions": 285, "similar_positions": 69, "identity": "53.17%" }, { "cls_id": "homologset.agr.MGI:2444584", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7T9-1", "uniprot_id": "D4A7T9_RAT", "id": "D4A7T9-1", "name": "Deubiquitinase MYSM1", "aln": "MEAEEADVDVEGDVAAAA--QPGNDGNTASVFQ-DHYLDSTWRRENGCLPWTLDSTISDENRAVIEKMLLEEEYYLSNKSLPGKFWVNQKENDKKCTN--------RVRSPAKPSSYSVKWTIEEKKLFEQGLAKFGRRWTKIAALVKSRTVLQVKSYARQYFRNKVKWGAEKETPTLKSNSDLQVKNKDERTKVWVAS------DPNLNAVKIEKLSDDEDVDITDELDELTSQTSQKNYGGHLTLDVPSSKMYKTNQGELCQ----EGSLAKSAEENLQNVKQSEAEACSSSEIMSWAEKQNNNGKNSVELN-EKYSKLVEEYTMLT-----EETKHSPSPEPCEGQKDPRGNELLLPPCQVEEENHEGEELKPPEQEVEIDRNVIQEEEKQAIPEFFEGRQTKTPERYLKIRNYILDQWEICKPKYLNKTSVRPGLKNCGDVNCIGRIHTYLELIGAINFGCEQAIYNRPQPVDKVRVTDRKDAEAAYQLAWRLQSMRTRRRRVRDPWGNWCDAKDLEGQTFEHLSVEELARREEEEKCKPIKFSKASKLPKSSLDPFQLIPCHFFSGEKQEPFQVKVASEALLIMDLHAHVSMAEVIGLLGGRYSEADKVLEVCAAEPCNSLSTGLQCEMDPVSQTQASETLALRGCSVIGWYHSHPAFDPNPSLRDIDTQAKYQSYFSRGGAKFIGMIVSPYNRSNPLPYSQITCLVISEELSPDGTYRLPYKFEVQQMLEEPQWELVFEKTRWIIEKYRLSHSSVPMDRIFRRDSDLTCLQKLLECLRKTLSKVANCFIAEEFLTQVENLFLSNYKSKE------------------------------------------------ENGLAEENSAKELFMINEKCSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69Z66-1", "uniprot_id": "MYSM1_MOUSE", "id": "Q69Z66-1", "name": "Deubiquitinase MYSM1", "aln": "MEAEEADVDVEGDVAAAA--QPGNDESTASVFQ-DHYLDSTWRRENGCLPWTLDSTISDENRAIIEKMLLEEEYYLSNKSLPGKFWVNQKEDNKKYTNSLQKSSKAMVDSPAKPASHSVKWTVEEKELFEQGLAKFGRRWTKIATLLKSRTVLQVKSYARQYFKNKVKWDVEKETPTQKSSSDLQVKNKDDRTKAWAAACLRGSADPCLNAVKIEKLSDDEDVDITDELDELTSQTSQ-NSGSHLTLDVPNSKMYTTNQGELCQ----EGPLAKSSGESLQNVKQGEGEACSSSEIASWAEKQKSTDKNSAELN-EKYNKVVEEHTLHRGE-VREEAKHSPSPEPCERQ-DSSGNEMLLPPCQIEEENHEGEELKPPEQEVEIDRNVIQEEEKQAIPEFFEGRQTKTPERYLKIRNYILDQWEICKPKYLNKTSVRPGLKNCGDVNCIGRIHTYLELIGAINFGCEQAVYNRPQPLDKVRAADRKDAEAAYQLAWRLQSMRTRRRRVRDPWGNWCDAKDLEGQTFEHLSVEEMARRKEEEKCKPIKFSKASKLPKSSLDPFQLIPCNFFSEEKQEPFQVKVAAEALLIMNLHAHVSMAEVIGLLGGRYSEADKVLEVCAAEPCNSLSTGLQCEMDPVSQTQASETLALRGYSVIGWYHSHPAFDPNPSLRDIDTQAKYQSYFSRGGAKFIGMIVSPYNRSNPLPYSQITCLVISEEVSPDGTYRLPYKFEVQQMLEEPQWELVFEKTRWIIEKYRLSNSSVPMDRIFRRDSDLTCLQKLLECLRKTLSKVANCFIAEEFLTQIENLFLSNYKSKE------------------------------------------------ENGLAEEDSTKELFM-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VVJ2-1", "uniprot_id": "MYSM1_HUMAN", "id": "Q5VVJ2-1", "name": "Deubiquitinase MYSM1", "aln": "MAAEEADVDIEGDVVAAAGAQPGSGENTASVLQKDHYLDSSWRTENGLIPWTLDNTISEENRAVIEKMLLEEEYYLSKKSQPEKVWLDQKEDDKKYMKSLQKTAKIMVHSPTKPASYSVKWTIEEKELFEQGLAKFGRRWTKISKLIGSRTVLQVKSYARQYFKNKVKCGLDKETPNQKTGHNLQVKNEDKGTKAWTPSCLRGRADPNLNAVKIEKLSDDEEVDITDEVDELSSQTPQKNSSSDLLLDFPNSKMHETNQGEFITSDSQEALFSKSSRGCLQNEKQDE--TLSSSEITLWTEKQSNGDKKSIELNDQKFNELIKNCNKHDGRGIIVDARQLPSPEPCEIQKNLNDNEMLFHSCQMVEESHEEEELKPPEQEIEIDRNIIQEEEKQAIPEFFEGRQAKTPERYLKIRNYILDQWEICKPKYLNKTSVRPGLKNCGDVNCIGRIHTYLELIGAINFGCEQAVYNRPQTVDKVRIRDRKDAVEAYQLAQRLQSMRTRRRRVRDPWGNWCDAKDLEGQTFEHLSAEELAKRREEEKGRPVKSLKVPRPTKSSFDPFQLIPCNFFSEEKQEPFQVKVASEALLIMDLHAHVSMAEVIGLLGGRYSEVDKVVEVCAAEPCNSLSTGLQCEMDPVSQTQASETLAVRGFSVIGWYHSHPAFDPNPSLRDIDTQAKYQSYFSRGGAKFIGMIVSPYNRNNPLPYSQITCLVISEEISPDGSYRLPYKFEVQQMLEEPQWGLVFEKTRWIIEKYRLSHSSVPMDKIFRRDSDLTCLQKLLECMRKTLSKVTNCFMAEEFLTEIENLFLSNYKSNQ------------------------------------------------ENGVTEENCTKELLM-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGA4-1", "uniprot_id": "MYSM1_DANRE", "id": "Q5RGA4-1", "name": "Histone H2A deubiquitinase MYSM1", "aln": "MADELDVVDIEGDECDEI----VGDLSSAEILQ-DQYLQSAWRTNSSVLPWTLDSSISDENRQVIESMLLEEQYYFASKKAPKVAWTNEKTKVK--------------KPLVKSSAAQTRWAEEEKELFEKGLAQFGRRWTKIAKLIGTRTVLQVKSYAKQYFKNKPKAEPAAEVTSANVTSVSSIQPHVS---------------ALTNAVRIERLSDDEDVDITDDFSDSELQSKKQPERS-VSPDCNHHGELRPSLSDALL----HLPSESTAADGQADPDFSEDTEIHHSEIDSEAVEES--GNPFINLD--------------------SPSKHSLTGEEETELADKCESAECLEEEVEDQEEDEEEELRAPEQEVELDLNTITEEEKQAISEFFEGRPSKTPERYLKIRNYILDQWRRSKPKYLNKTSVRPGLKNCGDVNCIGRIHTYLELIGAINFNCDQAIYNRPRLVDRSRLKESKDSLEAYHLAQRLQSMRTRKRRIRDVWGNWCDAKDLEGQTYEHLSAEELAIRREEMKKKGPRPSKLPKQ-RGSFDPFQLIPCKTFGEERQEPYSVIVCAEALIVMDIHAHVSMGEVIGLLGGTYEEEDKVLKICSAEPCNSLSTGLQCEMDPVSQTQASEVLGVKGLSVVGWYHSHPAFDPNPSLRDIDTQAKYQSYFSRGGAPFIGMIVSPYNPSNSSPQSQSTCLLVQEEPGPSGSHKFPYQFNMQCSAEPPDWSEVMRRAEWVVFKYRLCHGSVPMDRLFRRDSSLTCLEKMLLSIRTVLERLS-EVDIETFLVQLESLFNTHFLSETGSSSTHLYETATQPQLLSFLSSEPISSSATEETSDGHDEPNTTGPDKLEQSCVEEEHDETVMQSTSAETV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * **:*** .. .:*.::* *:**:*:** :.. :*****.:**:*** :**.*****:**::.*. * * ::* . * . .*.:: ..:*: ***:***:***:********: *: :**********:***:** * *... : .:: . . . ***:**:*****:*****:..: *: : . : * .. .: . .:: : . .* *** : ::. .: :*: ::: : * : . : :*..* ***:.****:*:* * * *******.****** :*****************. .**************************************.*:**:****: :*: * : **: **:** ********:**:** **************:****.**:* *.** * : : * .: :.*:********: *. *:***:.* *.:***::*::******.******** *.* ***:::*:*************************.*.::* **:********************************* ********** .*. * ** ***::.** .*.*::::**:*::* * *:* *:.::.*:: ****.:.*****::*****.****:*:* .:*..*.::: . * **.::*.** ::: *: *:. .**: : :: ", "identical_positions": 397, "similar_positions": 201, "identity": "44.86%" }, { "cls_id": "homologset.agr.MGI:2444585", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1K5-1", "uniprot_id": "A0A0G2K1K5_RAT", "id": "A0A0G2K1K5-1", "name": "Trafficking protein particle complex subunit 11", "aln": "MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRR---ADRVPISFKVLPGDHEYPKCRSKRTSYEWYIPKGILKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDIIASERAAALCNVCELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRTAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELSFEHAAWMSKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQHAKALCNHDAAVVYPSPDPLETPTGVLDFYGQRPWRQGILSFDLSDPEKEKAGILAIQLKERSVVHSEMIITLLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEAWWTLLTSILTTALKCSYLMAQLKDYITYSLELLGRASTLKDDQKSRIEKNLMNVLMNESPDPEPDCDALAVKTAQKLWADRVSLAGSNVFTIGVQDFVPFVQCKAKFHAPSFHVDVPVQFDVYLKADCPHPIRFSKLCVSFNNQGYNQFCVLEEASK----------------ASEVLENLTQG------KMCLVPGKTRKLLFKFVAKTEDVGKKIEITSVDLFLGSESGRCVVLSWQ-------------GGGGDAASSQEALQAARSFKRRPKLPDDEVHWDSIIVQASTMIISRVPNISVHLRHEPPALMNEMYCLVVTVQSQEKSQIRDVKLTAGLKPGQDANLTQKTHVTLHGAELCDESYPALLTDIPVGDLNPGEQLEKTVYVRCGTVG----SRMFLVYVSYLINTTVEGK------------------GIMCKCHKDETVTIETVFPFDVAVRFVSTKFEHLERVYADIPFLLMT------------------------------------------------------------------------------------------------------------DILSASPWALTIVSSELQLAPSMAAMDH---------LESQIDKVVLQTGESASECFCLRCPSAGNLEGG--------------------VATGHYIISWKRSSGMENIPAISTIITLPHVIVENIPLHVNADLPSFGRVRESLPVRYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTKQEMLYNFYPLMAGYQQLPSLNINLLRFPN---------FTNQLLRRFIPTSIFVKPQGRLLEDTSIAAA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RXC1-1", "uniprot_id": "TPC11_MOUSE", "id": "B2RXC1-1", "name": "Trafficking protein particle complex subunit 11", "aln": "MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRR---ADRVPISFKVLPGDHEYPKCRSKRTSYEWYIPKGVLKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDVIASERAAALCNVCELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRIAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELAFEHAAWMAKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQHAKALCNHDAAVMYPNPDPLETQSGVLDFYGQRPWRQGILSFDLSDPEKEKAGILAIQLKERSVVHSEIIIALLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEAWWTLLTSILTTALKCSYLMAQLKDYITYSLELLGRASTLKDEQKSRIEKNLMNVLMNESPDPEPDCDVLAVKTAQKLWADRVSLAGSNVFQIGVQDFVPFVQCKAKFHAPSFHVDVPVEFDVFLKADCPHPIRFSKLCVSFNNQVYNQFCVLEEASK----------------ASEVLENLTQG------KMCLVPGKTRKLSFKFVAKTEDVGKKIEITSVDLFLGSESGRCVVLSWQ-------------GGGGDAASSQEALQAARSFKRRPKLAEDEIHWDSVIIQASTMIISRVPNISVHLRHEPPALMNEMYCLVVTVQSHEKSPIRDVKLTAGLKPGQDANLTQKTHVTLHGAELCDESYPALLTDIPVGDLHPGEQLEKTVYVRCGTVG----SRMFLVYVSYLINTTVEGK------------------EIICKCHKDDTVTIETVFPFDVAVRFVSTKFEHLERVYADIPFLLMT------------------------------------------------------------------------------------------------------------DVLSASPWALTIVSSELQLAPSMTAMDH---------LESQIDKVVLQTGESASECFCLRCPSAGNIEGG--------------------VATGHYIISWKRASVVESIPAVSTVITLPHVIAENIPLHVNADLPSFGRVRESLPVRYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTKQEMLYNFYPLMAGYQQLPSLNINLLRFPN---------FTNQLLRRFIPTSIFVKPQGRLLEDTSIAAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z392-1", "uniprot_id": "TPC11_HUMAN", "id": "Q7Z392-1", "name": "Trafficking protein particle complex subunit 11", "aln": "MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRR---ADRVPISFKVLPGDHEYPKCRPKRTSYEWYIPKGILKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDVIASERAAALCNACELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRTAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELSFEHDAWMSKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQLAKTLCNHEASVMYPNPDPLETQTGVLDFYGQRSWRQGILSFDLSDPEKEKVGILAIQLKERNVVHSEIIITLLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEGWWTLLTSVLTTALKCSYLMAQLKDYITYSLELLGRASTLKDDQKSRIEKNLINVLMNESPDPEPDCDILAVKTAQKLWADRISLAGSNIFTIGVQDFVPFVQCKAKFHAPSFHVDVPVQFDIYLKADCPHPIRFSKLCVSFNNQEYNQFCVIEEASK----------------ANEVLENLTQG------KMCLVPGKTRKLLFKFVAKTEDVGKKIEITSVDLALGNETGRCVVLNWQ-------------GGGGDAASSQEALQAARSFKRRPKLPDNEVHWDSIIIQASTMIISRVPNISVHLLHEPPALTNEMYCLVVTVQSHEKTQIRDVKLTAGLKPGQDANLTQKTHVTLHGTELCDESYPALLTDIPVGDLHPGEQLEKMLYVRCGTVG----SRMFLVYVSYLINTTVEEK------------------EIVCKCHKDETVTIETVFPFDVAVKFVSTKFEHLERVYADIPFLLMT------------------------------------------------------------------------------------------------------------DLLSASPWALTIVSSELQLAPSMTTVDQ---------LESQVDNVILQTGESASECFCLQCPSLGNIEGG--------------------VATGHYIISWKRTSAMENIPIITTVITLPHVIVENIPLHVNADLPSFGRVRESLPVKYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTEQEMLYNFYPLMAGYQQLPSLNINLLRFPN---------FTNQLLRRFIPTSIFVKPQGRLMDDTSIAAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1RLX4-1", "uniprot_id": "TPC11_DANRE", "id": "Q1RLX4-1", "name": "Trafficking protein particle complex subunit 11", "aln": "MSPARWDLPPELCCRPMAFVALTGLDVVYNAIHRAIWDAFCANRR---ADRVPISFKVLPGDHEYPKCRTKRTSYEWYIPKGILKTGWMNKHLNLVPALVVLFYELDWDDPQWKEKQSECATKVEIVRTSLQGRNTKVAVVLIQKKTPLPPGEDLVASERASALCGACDLSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYNEIRRVKSHKEFLNKTTHQLLFVRHQFKMGFFSELKQDTQNALKYYRTAYSLVHELRAHETNVLEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELAFEHTAWMSKQFQSFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQQAGQLCSHEPGVGYPAPDPLETTSGALDFYGQRPWRQGHQSIDPPDSEKEKQGILALQVKERDVLHSELIIALLSNAVAQFKKYKCPRMKSHLMVQMGEEYYHAKDYTKALKLLDYVMCDYRTERWWSLLTSIVCTALKCSYLMGQVKDYITYSMELVGRASILSEEQKSRIEKNLIKVLMNEVPEPEPDCDPVSVKAAQSLWSDRVSLAGNNEFTIDVQDYVPFVQCKAKFLSPSFHIDEPVQLHVYVRADCPHPVRFSKLCVSLSNQEYNQYCLLEDAYK----------------GKDILEPSSQE------NMCLVPGKTRKYCFNFVAKTEDVGKKIEITSVGLMLGRETGRYVYLNWR-------------GGWGDAASSHESLQASRSFKRRTRLPEQHVDWDAVSVQSSTMIISRVPKISVQLTHEPPALTNEMFCMTVTIKSEEDTVGKDIKLTAGLKPGQDANLTQSTQITLNGSEVCDDSHPALLPDIPLGDLQPGQKIVKPLYIRCVSTG----SRIFLFHVAYSVSATVEGK------------------DITCKCHKDETVTVETVVPFEVAMKFVSSKFEHLERVYVDIPFLLMM------------------------------------------------------------------------------------------------------------DILSASPWPIELVESEVQLASSMTAIDQ---------PQSQVEGVTLQTSECASECFLLKCPPVQNGTST--------------------VASGHYIISWKRKSTFTETSVVRTVITLPHVMVENIPLYVHAEVPSFGRVRESLPVRYHLENRTGLVQDVEISVEPSDAFMFSGLKQVRMRILPGAEQEMLYNFYPLMAGYQVLPQLNINLLRFPN---------ISSQLLRRFLPSRIFVKPQGR-NGDASIEAA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRE3-1", "uniprot_id": "Q8IRE3_DROME", "id": "Q8IRE3-1", "name": "Trafficking protein particle complex subunit 11", "aln": "MTMDATALPSELLVTPQPLVGFCGLDTARVSVHKAVWEAFSGSLQRKAADRAAVQYKLLPPNYEFPVAKPKRASYEWYHPKGILKRNWMLKHLHVLPSVVVLFQDMEWNDLQWTEKQVQCAAIVQALKNTLQERNTRLCLVLLQRAAPLPPGEDLLAAERAASLTNACGITSKMLFILPHTEHLTGYALRLESAFLDMAQSYYALMSKRIRNHRDQLT-AAHTSLKIRHQFKLGFVAEMRQDFSTGQKHYFQAYANLDEIRINDGNCLEIKTLAGFLNYKICRLMFKLKTPRDAINQFIIHVEKHKSRVGFKDLAFEHHAWLSTQHSVFAELFCEAIKNGLPALQTQHPGIYYHKAAEFVMKRRDAAMEAYAAMQASSEATPTPIQNPLSLYTEFFG------IRAVKTGDLVAEQQANMQLCDQERSYNHSAAIIALLSQAMAQFKIYKCLRFRKKLAIDMAEEYLKSGDHAKALTLYSLMLPDYRQEKWTTIFTDVLLKTLRCALLSGSVADYIACSVEALSLRHQSDQSERILILENLWQVFQGVPPMP----KTQLTPEAQALWTSALANVKSP-IQIDLDKVNDVVEMCATFERVQLSNDDLLQLQLIVRVLTDIPLRIRSFHVILADAGNPQNSYKLEALKYFCFPTLTQLRGQKQPDDEQLENPSQEPKNFEKNMRLEPGSYYQLFCSTEAQQFHENTQLRIVRLEAHMGTDQVAALLTCSSNYSRQLFRHHTRSRDLDDNVTINPICYIAPTFHLDTQTNLGHGHDNGLTDDKEMVATKMLVNEYFPVVTTVSNPYNVYLQNVGVHISIPVGLRNSVFLTTDISPGRQKLHSQIQIDVGELSAHGSNTATFYIFSLTEAEIKLAQRLSYTLDVDRGPGGGGSNARVSTAPNSSESTPDHEVKSVIPSVAAISPVQIEYLDETRLRKSREDTLTVRCYGDFKFNARFYTMDRKPLNQVYRGENFLLRANTEVVAVDDVEILDSFFICDHNLVQSNYSFKQKKYTNKYSAGEQLESVIVLRTNATLRDWATARDLDHRGKLEGKAVASKFIRPVPKPSSEEPLAPTPPAGISAYMSKSLVTKIPTTMTIINSNSAVSNALQVANAGVMSNSTQSDDVNVAEEAINTHEGIKTTRLIYNKALEAVQGTGHCRGFIKKIYTLEGNPSAVPIFGVFCIRWRRAN-CKEENESKFVIRGLDIAEPPLNIYCTIEEKMFVKMPMAFKVVLKNPTTHVLHLIANLSISKTDNFICSGHKQLDISIMAYEEKELVYNLYPLQVGWQELPVLSLEYNTKADPQKKDSQNALLDELVQRALPKRVFVLPPLKQQNK------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :* ** * .:* : ***.. ::*:*:*:**... : ***..:.:*:** ::*:* .:.**:***** ***:** .** ***:::*::**:* :::*:: **.*** :**: *: :: :** ***::.:**:*: :*******::*:***::* ..* ::.* **:****:**.** :***.** : **:** :*::.*:: *. ::* * :*****:.*.:*::** ... * * ** :.*:* :: * *****:***:******* *: :** *** ** *:: *.::* :*:*** **::.*.. *.:** **** **.*:***:**:**::** :. :*:: * . . * *::. . : :.. * *: . : : :**. ** **:***:*:**** *** *::.:* ::*.*** : *::***.* . :: *** * * :::*.:: .:*:*: * ..: ***: *:* :. .:.:: * :** :*: . * * . . ** **:. :: . . : *.::. .*: *.* .: * :::.: ::. *:*: .: * : : * . :* * .: ** :* :* * **. : . *: . ..::.*. : :* : : . .* .: : : :*: .: . . :.: : . : . : : . : . * . . * ..: **:.:.**:: :* . . : .:: . : .:. .::: .::: : : . * :*: : .. * * : :::*:*:. *.. :* : . : *::** . *** .::: * .: ::.*: :: :: . : : :: ::* * . : . . * : * *:* . . :* .: : :: : * :: :: * : . * .::*:. :* *: ** **: : *:. ::*::**:*** .*:* ** *.:: .: : .:*::* :*. :** * : . ", "identical_positions": 305, "similar_positions": 392, "identity": "22.78%" }, { "cls_id": "homologset.agr.MGI:2444588", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IND4-1", "uniprot_id": "Q8IND4_DROME", "id": "Q8IND4-1", "name": "", "aln": "----------------------MDADESFLNQRSLLMDVMKQLEDLQNANKMDTGTKGKEEKKPEVDPSEGVTITNFMVFARDVRK------KSSRYLKRVQKMSNIN----QISFMRQIDVSPKDRAEARRDREIVADSFRRLGNEEYRRTNYEKAVYFYSKAIQYVADSPVLYCNRALAKIKKRDFKLALFDLDYVIFNLDPIHLRAWLYRAGALARLNNESEFEIAIANARLLNRS--QKDKKYIEYFLEKFKTEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JQU5-1", "uniprot_id": "A8JQU5_DROME", "id": "A8JQU5-1", "name": "Tetratricopeptide repeat protein 12", "aln": "----------------MYSLQHPQIDECFLDSESTVEEVVRLLENLQVPNEEE--AEGQEKPKRSLKSST-ITEESFIITERKTPIPVISAPTSSKEKSKPRTFNRIDRSKDRFPFMRQVEMDLDQRSKARLERERVAQNFRKLGNAEYRKGNYEAAMKVYTEAIENIRDSHILYINRALCFIKSGKFKRGIVDCDFVLNKLDEKNLRAWMYRAMAYKGLNDESNFENCVKYARKFNSK--QMD--FIDDFLEKLK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VC34-1", "uniprot_id": "Q9VC34_DROME", "id": "Q9VC34-1", "name": "CG6980-PA", "aln": "MANEEVKDNAQLKATMLNCNLNPSVADDFAEFEATLAKIDCILQNKAPCDDEDSKAGGDAKEKINFDNLD-VDKVRLKVKENRTVIN-----RKSLEEDNEKQVKDMN----QKSFMEQVEKDANDRAEARAKAEYEAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEKLQESNLRAWLYQAHAYKGLKQDDKFEESVVKAREHNPK--QLA--YIDKYIKQLEADLKALEI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8I6GMH4-1", "uniprot_id": "A0A8I6GMH4_RAT", "id": "A0A8I6GMH4-1", "name": "Tetratricopeptide repeat protein 12", "aln": "-MAKVGKNYTPPPALRFVSAMADDQERDLQRFLENVDEITNLIQEMNSDDPFIQQKAVLDTEKKLLLMEREQEEDGCRTTLNKTMIS---PPQAPEN------ANEMN----PDAFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVKGDYETAIFFYSEGLGKLKDMKVLYTNRAQAYIKLGDYQKALVDCDWALK-CDENCTKAYFHMGKAHLALKNYSKSKECYQKIGEINPKLKAQVKEHLNQVTLREKADLQEKKARESLDSGKNTAMTTRNLLETLSKPGQTPLFYAGGIEILTEMMTDCTERTLFRTYGGFSIINDHEVIKRCLFLAGKDAVEEIVCVSVLKLWQEVCIDNEENQRLLLSHPDMAKLLPSFMDSRILVIQQQSLALLLQLTQTDNGRNQVIKHLDMTRLCEALLSFLDFSDKKANTAIGLFTDLALEERFQVWFHANLPDVLPALTGALKREPKLTSPSALCQCIALMGNISAEPTARRHMLAYEEFGDACLDLLVKCEEDMDLYREVTYTLLGLIMNLCLEVPFLSESWAMKISRKCLSLLNSQDGGILTRAAGVLSRTLSSSQTIVEEALTAGVVKKMIKFLKTGGPTASRYAMKTLAVCTNSYHAAREEVMRLDKKFNVLMTLLASEDEVVVGNAALCLGNCMEVPSAASSLLKTDIMRVLLKLAGGDSQETAVQLNAGIALGKLCTAEPRFAVQLQELHGIQILNSTMKHLNDS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BW49-1", "uniprot_id": "TTC12_MOUSE", "id": "Q8BW49-1", "name": "Tetratricopeptide repeat protein 12", "aln": "--------------------MADDQERDLQRFLENVDEITSLIQEMNSDDPFIQQKAVLDSEKKLLLMEREQEEDGCRTTLNKTMIS---PPQTPEN------ADEMS----PDAFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALK-CDENCTKAYFHMGKAHVALKNYSKAKECYQKIEEINPKLKAQVKEHLNQVTLREKADLQEKEAQESLDSGKNTAVTTKNLLETLSKPGQTPLFYAGGIEILTEMMADCTERTLFRTYGGFSTISDHEVIRRCLFLTGKDAVEEVLCVSVLKLWQEVCVDNEENQRLLVTHPDMARLLPSFMTSRILVIQQQSLDLLLQLTQTENGRNQVIKHLDMTQLCEALLSFLAFSDKKANTAIGILTDLALEERFQVWFQTNLPDVLPALTGALNREPKITSPSALCQCIALLGNISAEPTARKHMIAHEEFGNACLDLLVKCEEDMDLFREITYTLLGLIMNLCLEITFLSEMWVVKMSRKCLSLLNSKDGGILTRAAGVLSRTLSSSQTIVEEALTAGVVKKMIKFLRMGGQTASRYAIKILAICTNSCHAAREEVVRLDKKFDLLMLLLASEDEILAGNAALCLGNCMEVPSAAPSLLKTDIVRVLLKLAGSDSKETGVQLNAGIALGKLCTAEPRFAAQLRELHGIQVLNSTMKHLNDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H892-1", "uniprot_id": "TTC12_HUMAN", "id": "Q9H892-1", "name": "Tetratricopeptide repeat protein 12", "aln": "--------------------MDADKEKDLQKFLKNVDEISNLIQEMNSDDPVVQQKAVLETEKRLLLMEEDQEEDECRTTLNKTMIS---PPQTAMKS-----AEEIN----SEAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALK-CDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQTQVKGYLNQVDLQEKADLQEKEAHELLDSGKNTAVTTKNLLETLSKPDQIPLFYAGGIEILTEMINECTEQTLFRMHNGFSIISDNEVIRRCFSTAGNDAVEEMVCVSVLKLWQAVCSRNEENQRVLVIHHDRARLLAALLSSKVLAIRQQSFALLLHLAQTESGRSLIINHLDLTRLLEALVSFLDFSDKEANTAMGLFTDLALEERFQVWFQANLPGVLPALTGVLKTDPKVSSSSALCQCIAIMGNLSAEPTTRRHMAACEEFGDGCLSLLARCEEDVDLFREVIYTLLGLMMNLCLQAPFVSEVWAVEVSRRCLSLLNSQDGGILTRAAGVLSRTLSSSLKIVEEALRAGVVKKMMKFLKTGGETASRYAIKILAICTNSYHEAREEVIRLDKKLSVMMKLLSSEDEVLVGNAALCLGNCMEVPNVASSLLKTDLLQVLLKLAGSDTQKTAVQVNAGIALGKLCTAEPRFAAQLRKLHGLEILNSTMKYISDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B119-1", "uniprot_id": "A0A8M3B119_DANRE", "id": "A0A8M3B119-1", "name": "", "aln": "--------------MNSVSTMS-LLDSDLEKFLRDVDQINELVRDLNSSEASCQENAIVKTEQLISSLEQKEQ---FKTKINKTVIN---TSSSENNPLNIRYESSQN----PENFLKILEKDAEDRCQRRKMKEERANVLREQGNEAFTQGDYETAVRFYTEGLEQLRDMQALYTNRAQAFIKLKRYKEAISDCEWALR-CNEKCIKAFIHMGTSHLALKDFTQSRICYRKILEIEPQRETMVKAYLRRVDMEEKVTLQEKAAWEELQEGTGQATNIADLLKKLERPNEINLYYCGGLELLSKAIKDCSGQTLFRLNNGFSIINGNITVRSCLSQNSKDPNAVDLCRSLIKLWRVVCSGNEQNQQLLMECSSARQHMVQLLASPFHEIHTESLQLLSMFAQTQHGRELIIHNLDSQQMAENLMICVCRN-TSSLSPLTLLENLASEKKFQIQSRENFTAIFALPLEDLLSNTTTADPKLLASVISVIGTIAQDDAISKNLAGRKEFWRCSLQAMEQCMG--CECGNVLYPLLGLMINLASNPSQVVQELAVPASSRCLGLLSHSSGGVITRAAGLLSVLLLLSSDATREAVQNGVVKKLLKMLKAGGEMSSRYSIKALTVCTASIPKAREELVKLDKRLHTLRNLLAVIDELVVGNAALCMGHCLEVDGAASCLLGTDCVALLLRHAAGDAKRAAVQQNAAITLGKLCKIEPRHMEKLRELHGLEILHSCMRLIT--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: :.: : : . . . . *: :: . .:*.: * . *: : ** : .** *: * :.: : * * *** . :* :: .: * ::.: : :*::: . : *:: . . : . .: . : ", "identical_positions": 19, "similar_positions": 58, "identity": "2.57%" }, { "cls_id": "homologset.agr.MGI:2444589", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80ZD3-1", "uniprot_id": "S2611_MOUSE", "id": "Q80ZD3-1", "name": "Sodium-independent sulfate anion transporter", "aln": "-------------------------------------------------------MAPD---T----------------------------------------CCCS--------ATALRRRLPVLAWVPDYSLQWLRLDFIAGLSVGLTVIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFRE-------------PAYAVLLAFLSGCIQLAMGLLHLGFLLDFISCPVIKGFTSAASITIGFGQIKNLLGLQKIPRQFFLQVYHTFLHIGET--RVGDAVLGLASMLLLLVLKCMR---EHMPPPHP--EMPLAVKFSRGLVWTVTTARNALVVSSAALIAYAFEVTG----SHPFVLTGKIAEGLPPVRIPPFSVT----RDNK------TISFSEMVQDMGAGLAVVPLMGLLESIAVAKSFAS-QNNYRIDANQELLAIGLTNVLGSLVSSYPVTGSFGRTAVNAQTGVCTPAGGLVTGALVLLSLNYLTSLFSYIPKSALAAVIITAVTPLFD-VKIFRSLWRVQRLDLLPLCVTFLLS-FWEIQYGILAGSLVSLLILLHSVARPKTQVS------EGQIFVLQPAS----------------------------------------------------GLYFPAIDALREA-----ITNRALEASPPRSAVLECTHISSVDYTVIVG------------------------------------------------------------------------------LGELLEDFQ-----KKGVALAFVGLQVPVLRTLLAADLKGFRYFTTLEEAEKFLQQEPGTEPNSIHEDAVPEQRSSLLKSPSGP---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M067-1", "uniprot_id": "F1M067_RAT", "id": "F1M067-1", "name": "Sodium-independent sulfate anion transporter", "aln": "-------------------------------------------------------MAPD---T----------------------------------------HCCS--------RADLRRRLPVLAWLPNYSLRWLRMDVIAGLSVGLTVIPQALAYAEVAGLPPQYGLYSAFMGCFVYFVLGTSRDVTLGPTAIMSLLVSYYTFRE-------------PAYAVLLAFLSGCIQLAMGLLHLGFLLDFISCPVIKGFTSAASITIGFGQVKNLLGLQNIPRQFFLQVYHTFLHIGET--RVGDAILGLVCMVLLLVLKLMR---EHIPPPHP--EMPLGVKFSRGLVWTVTTARNALVVSFAALIAYAFEVTG----SHPFILTGKIAQGLPPVRMPPFSVT----TDNK------TISFSEMVQDMGVGLAVVPLMGLLETIAVAKSFAS-QNNYRIDANQELLAIGLTNVLGSLVSSYPVTGSFGRTAVNAQTGVCTPAGGLVTGVLVLLSLDYLTLLFYYIPKSALAAVIIMAVAPLFD-VKIFRRLWLVQRLDLLPLCVTFLLS-FWEIQYGILAGTLVSLLILLHSVARPKTQVS------EGQILVLQPAS----------------------------------------------------GLHFPAVDALREA-----MTKRALEASPPRSAVLECTHVSNIDYTVILG------------------------------------------------------------------------------LGELLEDFQ-----KKGVTLAFVGLQVPVLRTLLAADLKGFQYFTTLEEAEKSLQQEPGTQPYSIREDTAPEHRSSLLKSPSGP---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86WA9-1", "uniprot_id": "S2611_HUMAN", "id": "Q86WA9-1", "name": "Sodium-independent sulfate anion transporter", "aln": "--------------------------------------MPSSVTALGQARSSGPGMAPS---A----------------------------------------CCCS--------PAALQRRLPILAWLPSYSLQWLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFHE-------------PAYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNIPRPFFLQVYHTFLRIAET--RVGDAVLGLVCMLLLLVLKLMR---DHVPPVHP--EMPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTG----YQPFILTGETAEGLPPVRIPPFSVT----TANG------TISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFAS-QNNYRIDANQELLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAVAPLFD-TKIFRTLWRVKRLDLLPLCVTFLLC-FWEVQYGILAGALVSLLMLLHSAARPETKVS------EGPVLVLQPAS----------------------------------------------------GLSFPAMEALREE-----ILSRALEVSPPRCLVLECTHVCSIDYTVVLG------------------------------------------------------------------------------LGELLQDFQ-----KQGVALAFVGLQVPVLRVLLSADLKGFQYFSTLEEAEKHLRQEPGTQPYNIREDSILDQKVALLKA-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VA55-1", "uniprot_id": "Q9VA55_DROME", "id": "Q9VA55-1", "name": "STAS domain-containing protein", "aln": "--------------------------------------MSTLENEVTFRKQAEVNQNLEAQFD--SSSTDFILITDHRTSKSKSLEQ---LEASKES--KNPESCCSRYARNIFRKKTLLKRLPFLTWLPHYNRQDCIGDLIAGFTVGLTVIPQGLAYSGVVGLPPEYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMTFQFAQGS-------------WQRSVLLTFLTGIIEILMAIFKLGCLVEFVSGPVSAGFTSAVALIVSTSQMRSMLGVKSDGGSFLATWISMFRDIENV--RVADTCLGFGCVILLLAMRSLG---KFTIGPKDESRRNGFQRVVNTVIKFLSTSRNASVVILFTAVTMYLDANG----TNPFRLTGNIPKGMPTPSLPPFSIEPQPGNETAGIPAVEGQTFPEMVQSLGYGLVIVPLMALLETMSVCKAFA---KGKQIDITQEMIACGVGNIATSLFSGYRCNGGLARSAVNNASGCRTNMSNLYIGVIVVLALNFLTEYIAFIPKAVLAAIIISAVIFQVQ-YQVVTPMWRSKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLLFILYYAARPKVTLEQLETQQGIRFVKITPDR----------------------------------------------------CLIFPSVEFVRN-------MVLKLGSKSTLPVVIDCTYIYAADFTAAKV------------------------------------------------------------------------------ISSIVDDFR-----RRQQKIIFFNLKPSVVSVFEGLNTRLVLCYNTHALNQELRPDEPDLSRSVDSLDHAESGNGTSECVSMASTLSLARS--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7H4-1", "uniprot_id": "Q9I7H4_DROME", "id": "Q9I7H4-1", "name": "Sodium-independent sulfate anion transporter", "aln": "--------------------------------------MSQRADSG--HTNSGFNGGSEVSLD--IPTN-----TLYHTSRDCIVQE---EQGPDESCLEGTQSCCSNLWSNIFRKKTLYKRFPILVWLPQYKKDYIFGDIVAGISVALTVIPQALAYAGIAGLDLQYGLYACFLGCFIYIFIGSSKDVPIGPTAISALLSFQIAGGS-------------WQIATLLTFLTGLIEILMGVFRLGFLIDFVSGPVGAGFTSAVSLIIFSSQMKDFLGIKTSGNTFLQVWISIVNDIHNI--SWPDFILGIVCITLLLSLRALA---SCTLGPKE--GKTTAQKLLTGIFWTIGTARNALLVCGTAGLGYWLFVNG---KENLVKTVGFVPKGLPSFQPPPFHMD-AVVNETTGEVLQEAQSFWDMVSTLGSGLIVVPLIALLETMAVVQAFA---DGKPTDATQELIASGVCNVANSFVQGLRSNGGIARGAILNASGVRTQLSNLYTSVIVIIALLYLTPCFYYIPKAALASIIIAAVIFMVQ-YRVIKPMWHSKKTDLIPGLGAFFACLVLPLQLGILVGIGINVVFILYQAARPKLRIETLATTTGLKYLMLTPDR----------------------------------------------------CLIFPSMEFVRK-------VINKQGQKSTLPVVIDCTHIYGADFTAAKV------------------------------------------------------------------------------ISTMVMDFK-----LREQPLFFYNLQPRVAQVFEGLNKDLVVIYDINTLHAKLAEKSPPI---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VC29-1", "uniprot_id": "Q9VC29_DROME", "id": "Q9VC29-1", "name": "", "aln": "--------------------------------------MKSNPASDHVYFNDGFKCSTISISTNLTEPNGSSNSVGSQGSKEFILTEDGKKVKPTVSTLDCTRSWLQDCQRRTFNRKTLHKRLPILGWLPKYNSQDAVGDLVAGITVGLTVIPQALAYAGIAGLPVAYGLYASFVGCFVYIFLGSCKDVPMGPSAIVALLTYQAAQGS-------------WQKSVLLCLLSGIVELLMGLFGLGFLIDFVSGPVSSGFTSAVSLIILTSQIQSVLGITAKGNTFVEIWTQVFHNIEHT--RAGDTVLGLTCIVILLLMRSLS---SCRIGPVDEKECSSFQRAVNKILWIVGTARNAILVVVCCIMGYMLHTEE---HGAPFRVVGEIPPGLPSIQLPPTSLT---ANETS---NGVAEGFVEMVHSMGSGLVVIPLISLMENIAICKAFA---NGKPVDASQELIAIGTANIFNSFVQAFPGTGALSRGAVNNASGVRTPLSNIYSGGLVMIALLFLTPYFYFIPRPTLAAIIISAVVFMIE-VKVVKPMWRSKKSDLVPGVGTFVACLVLPLEWGILIGVGLNVIFILYHAARPKLSTELLTTQSGVEYSMITPDR----------------------------------------------------CLIFPSVDYVRN-------LVNKQSIRQNVPVVIDASHVYGADFTTATV------------------------------------------------------------------------------IDSLISDFN-----QRGQLLFFYNLKPSICSIFEHVSAAQFVVYYQEQQLDELLKERNYVQKRLETA--------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAC2-1", "uniprot_id": "Q9VAC2_DROME", "id": "Q9VAC2-1", "name": "STAS domain-containing protein", "aln": "--------------------------------------MRDNEDDLYRERLPNVCGAVSSKAR----------------------------------------SCCS--------MRSVHRYLPVTDWLPKYQLNFLAMDVVAGLTVGLTAVPQAIAYGAVANLPPAYGLYSAFMGGFVYILLGTCKDITVGPTAIMALMVQPYVDGN-------------PAYAVLICFLSGCIITLMGLLNLGVLMRFISVPVTTGFTMAAALTIATGQVNSLFGISSSASGFLNSWIYFFGHITQT--RRNDAILGCCTLVLLLLMRQLK---NLTFGFKS-------------VWKYISLARNAVAVLIGILLCYLLKNDG----KLPFLVSGSITPGLPPFKLPPFHTE---DPETG-----ETISFGGMVSNVGTALVSIPLLSILESIAVAKAFS---KGKIVDASQEMIALGVSNILSSFFSSMPITGSFTRTAINNASGVKTPLGGAVTGALVLMTLAFLTTTFAYIPKATLAAIIIAAMFFMVE-YETIGEIWRAKKRDMLPFLVTVLTCVFWTLEYGMVVGIVFNALFLLYKSMKPQFFLTTEKFN-GIEVTMADLKG----------------------------------------------------SVDYAAAEYLKMSLVSHVTQRNSEGSAPTTLVVIKGHEIASIDTTVALN------------------------------------------------------------------------------LKSLREDLA-----LLKCDMICWNWSIPAAGVICRMDRKLRSMFKFSKSFPDLMQTIADAEAADSCIAVDLSQ--------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VF65-1", "uniprot_id": "Q9VF65_DROME", "id": "Q9VF65-1", "name": "SLC26A/SulP transporter domain-containing protein", "aln": "---------------------------------------MRWPRKHTFGLWPKRNGRNRSSGEATGGQPQATVATIYDPGCEEKEKYTAQNGDDYYGQAHTVDLDVASKYSKPKEAHWLVRRIFFLSWITSYDREQAFADLIAGITLGLTIIPQSIAYAALAGLSSEYGLYSAFIGSIIYVFFGTIPQVSIGPTSLMAILTLQFCADKP------------VQVVIVLAFLAGLVELAMGVFQLGFIVSFIPAPVTKAFTSGTALIVVFAQIKNLLGVR------IKGFPSIGDFFTNI--RPTDAAMGISCMVVLLSLRLLS---QVNFKQDTP-----VTRRLKKILWYISISRNALVVFFTGLLVFIWVKKSSIE-AVPFALSSKVSSAMPTIKLPPFAFE----YQNR------TYVFTDILHELGSGIVVVPIVAVLANVAIAKAFVKD---GNLDASQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAGIYTGLIVLSALSILTPYFQYIPKASLSAVLIAAVIFMID-LAPVKELWQTNKKDFFSWVGSFIICLVAGVELGLLFGIVLSMVFILLRLGNPKFEVT-LKQHESTYYVHIVPQS----------------------------------------------------DVYYTGVDALRSE-----LRGACRLYHNDFPVVLDCARFMQFDATFSEM------------------------------------------------------------------------------LISVAKEMA-----SHDVLLILQNMSLKVQQMLPVMGN--VRFCQEDSQLSSHLQVEKEAP-------VVEAKL-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VF45-1", "uniprot_id": "Q9VF45_DROME", "id": "Q9VF45-1", "name": "SLC26A/SulP transporter domain-containing protein", "aln": "-------------------------------------------------MYPQLETEAEALEKAT--------ARALLPGAISKPASEAGKAPRMN-----------------KWKRRLHRHVPVFQWLPLYSTEWGIDDFIAGITLGLTIIPESMACALLAGLPARYGLCSAFIGPLIYMVFGSIDKVIIGPTSLVALVSVQFTVGRP------------IEFAFLLTFLSGIVQIIMGTMRMGFIFEFISMPVIKAFSSATAILVIESQLKVLLGIKYLVAGLMNSVGMLSSRIEES--NMADLIMGVCAIVFLLLLELLD---RVANNEKR-------NKILRIFCRYLSTSRNTLIVLIAAIVSFIWIQK--CG-QVPYALSKNALSTLPNFTVPSFHIE----TAER------NYSIWEVLKELNIGIIVIPIVGILTNISIGKLTPK----GLVDTNQELLTVGLCNMFGSCVQAMPSSGAFTRYAISTACGLRTPMANLYLGIIVLLALSYLSPYFNYIPEATLAAILICSIFTLLD-FKLPMRLWRDSKRDFATWLLCFCVSVLFGVEVGLFVSIVVTALHLLFLWARPEIRVK-IEQLDEMQYIRVTPSN----------------------------------------------------GIYFPAINYLRER-----VLKACEQADFRITVVIDGQRISGMDYTAAQG------------------------------------------------------------------------------ISKLSSDLCRQADASSSTLLILFRFPEHLQRLIDNTDN--LVFCESENKVKEFLTQESLRNGYINLKEHIRASIDLGYKIDID----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38359-1", "uniprot_id": "SUL1_YEAST", "id": "P38359-1", "name": "Sulfate permease 1", "aln": "MSRK-----SSTEYVHNQED----ADIEVFESEYRTYRESEAAE---NRDGLHNGDEENWKVNSSKQKFG--VTKNELSDV-LYD-SIPAYEESTVTLKEYYDHSIKNNLTAKSAGSYLVSLFPIIKWFPHYNFTWGYADLVAGITVGCVLVPQSMSYAQIASLSPEYGLYSSFIGAFIYSLFATSKDVCIGPVAVMSLQTAKVIAEVLKKYPEDQTEVTAPIIATTLCLLCGIVATGLGILRLGFLVELISLNAVAGFMTGSAFNIIWGQIPALMGYNSLVNTREATYKVVINTLKHLPNTKLDAVFGLIPLVILYVWKWWCGTFGITLADRYYRNQPKVANRLKSFYFYAQAMRNAVVIVVFTAISWSITRNK-SSKDRPISILGTVPSGLNEVGVMKIPDG--------------------LLSNMSSEIPASIIVLVLEHIAISKSFGR-INDYKVVPDQELIAIGVTNLIGTFFHSYPATGSFSRSALKAKCNVRTPFSGVFTGGCVLLALYCLTDAFFFIPKATLSAVIIHAVSDLLTSYKTTWTFWKTNPLDCISFIVTVFITVFSSIENGIYFAMCWSCAMLLLKQAFPAGKFLGRVEVAEVLNPTVQEDIDAVISSNELPN---------------------------ELNKQVK---STVEVLPAPEYKFSVKWVPFDHGYSRELNINTTVRPPPPGVIVYRLGDSFTYVNCSRHYDIIFDRIKEETRRGQLITLRKKSDRPWNDPGEWKMPDSLKSLFKFKRHSATTNSDLPISNGSSNGETYEKPLLKVVCLDFSQVAQVDSTAVQSLVDLRKAVNRYADRQVEFHFAGIISPWIKRSLLSVKFGTTNEEYSDDSIIAGHSSFHVAKVLKDDVDYTDEDSRISTSYSNYETLCAATGTNLPFFHIDIPDFSKWDV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12325-1", "uniprot_id": "SUL2_YEAST", "id": "Q12325-1", "name": "Sulfate permease 2", "aln": "MSREGYPNFEEVEIPDFQETNNTVPDLDDLELEYDQYKNNENNDTFNDKDLESNSVAKHNAVNSSKGVKGSKIDYFNPSDVSLYDNSVSQFEETTVSLKEYYDHSIRSHLTVKGACSYLKSVFPIINWLPHYNFSWFTADLIAGITIGCVLVPQSMSYAQVATLPAQYGLYSSFIGAYSYSFFATSKDVCIGPVAVMSLQTAKVIADVTAKYPDGDSAITGPVIATTLALLCGIISAAVGFLRLGFLVELISLNAVAGFMTGSAFNILWGQVPALMGYNSLVNTRAATYKVVIETLKHLPDTKLDAVFGLIPLFLLYVWKWWCGTYGPRLNDRYNSKNPRLHKIIKWTYFYAQASRNGIIIIVFTCIGWAITRGK-SKSERPISILGSVPSGLKEVGVFHVPPG--------------------LMSKLGPNLPASIIVLLLEHIAISKSFGR-INDYKVVPDQELIAIGVSNLLGTFFNAYPATGSFSRSALKAKCNVRTPLSGLFSGSCVLLALYCLTGAFFYIPKATLSAVIIHAVSDLLASYQTTWNFWKMNPLDFICFIVTVLITVFASIEDGIYFAMCWSCAMLILKVAFPAGKFLGRVEVAEVTDAYVRPDSDVVSYVSENNNGISTLEDGGEDDKESSTKYVTNSSKKIETNVQTKGFDSPSSSISQPRIKYHTKWIPFDHKYTRELNPDVQILPPPDGVLVYRLSESYTYLNCSRHYNIITEEVKKVTRRGQLIRHRKKSDRPWNDPGPWEAPAFLKNLKFWKKRENDPESMENAPSTSVDVERDDRPLLKILCLDFSQVAQTDATALQSLVDLRKAINQYADRQVEFHFVGIISPWVKRGLISRGFGTLNEEYSDESIVAGHTSYHVARVPQG-----EENPEKYSVYT-------ASGTNLPFFHIDIPDFAKWDI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . *.. *. *.:**:::. . :*:.:: . :. * *** ..*:* * .:.: . :*. :: :: : :* * : :. : :* :. ::. . .* . :. : .*: .:* : . * :* : .* . ** : : : :: :. : :: :: ::: : **::: * *: : . . *.: * *: . * .. . *: :* *: : :**.. *::::* :: . :* . * . . :: *: . . :: * : . . . . : : : :: ", "identical_positions": 44, "similar_positions": 128, "identity": "4.75%" }, { "cls_id": "homologset.agr.MGI:2444593", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A520-1", "uniprot_id": "D4A520_RAT", "id": "D4A520-1", "name": "Protein phosphatase", "aln": "-------------------------------------------MFSVLSYGRLVARAVLGG------------------------LSQTDPRAGGGGGGG---SGDYGLVTAGCGFGKDFRKGLLKKGAC---YGDDACFVARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKN-SNYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGG-KPDDITVLLSIVAEYTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NVE9-1", "uniprot_id": "PPTC7_MOUSE", "id": "Q6NVE9-1", "name": "Protein phosphatase PTC7 homolog", "aln": "-------------------------------------------MFSVLSYGRLVARAVLGG------------------------LSQTDPRAGGGGGGGGGSSGDYGLVTAGCGFGKDFRKGLLKKGAC---YGDDACFVARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKN-SNYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGG-KPDDITVLLSIVAEYTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NI37-1", "uniprot_id": "PPTC7_HUMAN", "id": "Q8NI37-1", "name": "Protein phosphatase PTC7 homolog", "aln": "-------------------------------------------MFSVLSYGRLVARAVLGG------------------------LSQTDPRAGGGGGGD------YGLVTAGCGFGKDFRKGLLKKGAC---YGDDACFVARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKN-SNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGG-KPDDITVLLSIVAEYTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U3N5-1", "uniprot_id": "PPTC7_DANRE", "id": "Q5U3N5-1", "name": "Protein phosphatase PTC7 homolog", "aln": "-------------------------------------------MLSVLSYGRLVARAVIGG------------------------LSQTDSRD-------------YSLVSASFGFGKDFRKGILKKGMC---YGDDACFIARHRSADVLG-VADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSN-----PVGILTTSYYELLQNKVPLLGSSTACIVVLDRQSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPE-------AEGSVLSDSPDAADSSSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKN-TNYESTQQTAKSIAEQAHVLAYDPNYMSPFAQFACDNGLNVRGG-KPDDITVLLSIVAEYTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACD6B694-1", "uniprot_id": "A0ACD6B694_DANRE", "id": "A0ACD6B694-1", "name": "Protein phosphatase", "aln": "-------------------------------------------MLSVLSYGRIVARAVLGG------------------------LSQTDGRD-------------YSLITASCGFGKDFRKGILKKGMC---YGDDACFIARHKSADVLG-VADGVGGWRDYGVDPSQFSATLMKTCERLVKEGRFTPSS-----PVGILTSGYYELLQNKVPLLGSSTACIVVLDRRSHRIHTCNLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPG-------AEGVVLSDSPEAADSSSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKN-TNYDSIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGG-KPDDITVLLSIVAEYTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3R1-1", "uniprot_id": "Q9W3R1_DROME", "id": "Q9W3R1-1", "name": "Protein phosphatase", "aln": "MDVETSLDIEEMRRRIQQGINRCCEQLLEIAMILTHKGGQVLNRLKGASFPELAQNSENIGNGSMSENQNQRLDPMTSAQYTTLGFGNFDGEGDYLRQKNKINIQLPRLVSVTCGFAKDHIRYPEYNRGK---FGEDAWFMSSSPQACIMG-VADGVGGWRNYGVDPGKFSMTLMRSCERMSHAPDFKPNR-----PEILLERAYFDLLDQKCPIVGSCTACILALKRDDSTLYAANIGDSGFLVVRSGKVVCRSQEQQHQFNTPYQLASPPPG-------YDFDAVSDGPESADTIQFPMQLGDVILLATDGVYDNVPESFLVEVLTEMSGISNPVRLQMAANTVALMARTLSFSPKHDSPFSQNARKHDIDAWGG-KPDDITVLLASVV----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0E2-1", "uniprot_id": "Q9W0E2_DROME", "id": "Q9W0E2-1", "name": "Protein phosphatase", "aln": "---------------------------MHSSLSWTSR---AISRALRSSFSTLLETATGGGSGAAAKGATK--------------SGATPGSSGAPR---------PRFVSVVCGFAKDNLRH-KYKPGK---YGEDSWFKASTASADVMG-VADGVGGWRSYGIDPGEFSSFLMRTCERLVQCSHFNPQR-----PVNLLAYSYCELMEQKKPILGSSTACVLILNRETSTVHTANIGDSGFVVVREGQVVHKSEEQQHYFNTPFQLSLPPPG-------HGPNVLSDSPESADTMSFPVRDGDVILIATDGVFDNVPEDLMLQVLSEVEGERDPVKLQMTANSLALMARTLSLNSEFLSPFALSARRNNIQARGG-KPDDITVVLATVAM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAH4-1", "uniprot_id": "PTC71_DROME", "id": "Q9VAH4-1", "name": "Protein phosphatase PTC7 homolog fig", "aln": "---------------------------MITCLR------NWPLLLKRFSVHQIHQFTQLSG-----------------------RFERPPQSGKSSRD--------PYLVTVVQGRSKKPRFPGERSNQR---FGEDSWFVSSTPLAEVMG-VADGVGGWRDLGVDAGRFAKELMSCCSGQTQLSDFDGRS-----PRNMLIAGFQELSHREHPVVGSSTACLATMHRKDCTLYTANLGDSGFLVVRNGRVLHRSVEQTHDFNTPYQLTVPPED-------RKESYYCDKPEMAVSTRHSLLPGDLVLLATDGLFDNMPESMLLSILNGLKE-RGEHDLLVGASRVVEKARELSMNASFQSPFAIKARQHNVSYSGGGKPDDITLILSSVEVPNA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38797-1", "uniprot_id": "PP2C7_YEAST", "id": "P38797-1", "name": "Protein phosphatase 2C homolog 7, mitochondrial", "aln": "-----------------------MFANVGFRTLRVSRGPLYGSCSQIISFSKRTFYSSAKSG-----------------------YQSNNSHGDAYSSGSQSGPFTYKTAVAFQPKDRDDLIYQKLKDSIRSPTGEDNYFVTSNNVHDIFAGVADGVGGWAEHGYDSSAISRELCKKMDEISTALAENSSKETLLTPKKIIGAAYAKIRDEKVVKVGGTTAIVAHFP-SNGKLEVANLGDSWCGVFRDSKLVFQTKFQTVGFNAPYQLSIIPEEMLKEAERRGSKYILNTPRDADEYSFQLKKKDIIILATDGVTDNIATDDIELFLKDNAA-RTNDELQLLSQKFVDNVVSLSKDPNYPSVFAQEISKLTGKNYSGGKEDDITVVVVRVD----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . . :. . *:* * : ::. ******** . * *.. :: * . * :: .: .: ..: :*. ** : : : ..*:*** *.* ..:: :: * **:*:**: * : * * . : *::: ****: **:. : *. : .. . *: .... * *: . .* * ****::: * ", "identical_positions": 52, "similar_positions": 70, "identity": "13.16%" }, { "cls_id": "homologset.agr.MGI:2444594", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BU91-1", "uniprot_id": "S26A9_MOUSE", "id": "Q8BU91-1", "name": "Solute carrier family 26 member 9", "aln": "-----------------------------------------MNQPRPRYVVDRAAYSLSLFDDEFEKKDRAYPVG--------EKLRNTFRCSSAKFKAFVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGCIQVPQGMAFA-LLANLPAVNGLYSSFFPLLTYFFLGGIHQMVPGTFAVISILVGNICLQLA----------------------PESKFQIFNNVTNETYVDTAAMEAERLH-------------VSATLACLTAVIQMALGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLT------IPSYTGPGSIVFTFIDICKNLPHTNIASLIFALVSGVFLVLVKELN-ARYMHKIHFPIPTEMIVVVVATAISGSCKMPKKYHMQIVGEIRQG----FPTPVA-PMVSQWKGMVGTAFSLAIVGYVINLAMGRTLASKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGSYLYPLPKAVLGALIAVNLKNSLKQLTDPYYLWRKSK--LDCCVWVVSFLSSFFLSLPYGVAVGVAFSILVVIFQTQFRNGSTLAQVMDTD-IYVNPKTYNRAQEIAGVKIVTYCSPLYLANSEIFRQKVIAKTGMDPQKVLLAKQKYLRKQEKRTAIPTQQRKSLFMKTKTVSLQELQQDFESAPSTDPNNNQAPAAEAHISYITFSPDASTAAACELPASTRSPQEASDTLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYEKIGVQIFLVNIHAQVYNDISHGGVFEDGCVQRSHVFPSIHDAVLFAQANAREA-PDRNFHGAPGDTEFSLYDSEEEGPSYWDLEQEMFGTMFHTETLTAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZV32-1", "uniprot_id": "D3ZV32_RAT", "id": "D3ZV32-1", "name": "", "aln": "-----------------------------------------MSQTRPRYVVDRAAYSLSLFDDEFEKKDRAYPVG--------EKLRNTFRCSSAKLKAIVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGCIQVPQGMAFA-LLANLPAVNGLYSSFFPLLTYFFLGGIHQMVPGTFAVISILVGNICLQLA----------------------PESKFQIFNATTNETYVDTVAMEAERLH-------------VSATLACLTAVIQMALGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLT------IPSYTGPGSIVFTFIDICKNLPHTNIASLVFALVSGVFLVLVKELN-ARYMHKIHFPIPTEMIVVVVATAISGSCKMPKKYHMQIVGEIRHG----FPIPVA-PMVSQWKDMVGTAFSLAIVGYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGSYLYPLPKAVLGALIAVNLKNSLKQLTDPYYLWRKSK--LDCCVWVVSFLSSFFLSLPYGVAVGVAFSILVVIFQTQFRNGSTLAQVMDTD-IYVNPKTYNRVQEIEGVKIVTYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLRKQEKRMAVPTQQRKSLFMKTKTVSLQELQQDFESAASTDPNNNQAPVADAHISYITFSPDSSATAASELPTSTQSPREASDALASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYEKIGVQIFLVNIHAQVYNDISQGGIFEDGCVQRNHVFPSIHDAVLFAQANAREA-PAHNFQGAPGDTEFSLYDSEEDGSSYWDLEQEMFGTMFHTETLTAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7LBE3-1", "uniprot_id": "S26A9_HUMAN", "id": "Q7LBE3-1", "name": "Solute carrier family 26 member 9", "aln": "-----------------------------------------MSQPRPRYVVDRAAYSLTLFDDEFEKKDRTYPVG--------EKLRNAFRCSSAKIKAVVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGSIQVPQGMAFA-LLANLPAVNGLYSSFFPLLTYFFLGGVHQMVPGTFAVISILVGNICLQLA----------------------PESKFQVFNNATNESYVDTAAMEAERLH-------------VSATLACLTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLT------IPSYTGPGSIVFTFIDICKNLPHTNIASLIFALISGAFLVLVKELN-ARYMHKIRFPIPTEMIVVVVATAISGGCKMPKKYHMQIVGEIQRG----FPTPVS-PVVSQWKDMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLWRKSK--LDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD-IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQGAPGDAELSLYDSEEDIRSYWDLEQEMFGSMFHAETLTAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VVM6-1", "uniprot_id": "Q9VVM6_DROME", "id": "Q9VVM6-1", "name": "", "aln": "--------------MPSDKESPETKPLNNNNTNGNGGSVPSKPKIQPKYSIHRDVLTHEVVIKQTGYAARDKSIP--------SSLRNCWRS--WNFFALFTGVIPILQWLPQYSPRRDLPGDIIAGFTVAIMNIPHGMAYG-ILAGVSAGNGLYMAVFPVLAYMFLGTSKHISIGTFAVASMMTAKVVDTYANVDDHHQILPINAFGLQSNGTATASPLLLINSSALADSVSSTTISPFQLLNSTLNADPITKIEVATSLALTVGIVNLLMAFLRLGTLSSLLSEPLVNGFTTAAACHVVTAQLKDVLGIS------VPRHKGAFKIIYTVIDVIKGVPQTNLVNFGFCMAVIAFMMICNEILKPRLSKKCRFPLPAELIMVIGGTLISKWFNLYVDYNVNPVGKIPSG----LPEPVL-PRLDLVPKVAVDSIAIAIVTYSIIMSMGLTFAKKHGYEVRPNQELFAMGIGNMVGGCFSCIPMACSLSRSVIQDQTGGVSQIASLVSASLVVVTLMWIGPFFSSLPRCVLAGVIIVALKPMFMQAKELKKFSKQGK--LEMFTWISTFLCVVIIDIDIGLLIGICISLLALYIKGLKPYSCLLGYMPEAPGIYMDLNQHRNAMQVPEVRIFRYSGSLNFATSLFFRRALYEAVGLDK--------------------------------------------IPLTKVSSSNSNSPSKGSKSSYSPVSQNGGKAINGKLEETSG----------------AFKVLVLDFSMLGHIDVAGCRTLTDLSKELKVRGARLLLASPVDRVYDTLVHSMALSEG---PFEIFPTLHDCVEYANACRTA------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53394-1", "uniprot_id": "SULX_YEAST", "id": "P53394-1", "name": "Putative sulfate transporter YPR003C", "aln": "MTSNNSLLGRGRMSYSSTAPPRFKRSVDQRDTFSDNFDYDKDSSNRGRTYIAASNSTTGVPPPNNSRSGCTNNTNNTNNTSNTSNTNNNDSVDENTVFETLPYYLPCFSWLPEYTFN-KLWGDVIAGISVASFQIPLALSYTTSIAHVPPLCGLYSLAISPFVYGILGSVPQMIVGPESAISLVVGQAVESIT--------------------------------------LHKENVSLIDIS---------------TVITFVSGTILLFSGISRFGFLGNVLSKALLRGFISSVGLVMIINSLISELKLDKFLVSLPQHYHTPFEKILFLIDYAPAQYHIPTAIFSGCCLIVLFLTRLLKRKLMKYHKSAIF-FPDILLVVIVTILISMKFNLKHRYGISIIGDFSMDNFDELKNPLTRPRRKLIPDLFSASLIVAMLGFFESTTASKSLGTTYNLTVSSNRELVALGFMNIVISLFGALPAFGGYGRSKINALSGAQSVMSGVFMGVITLITMNLLLQFVHYIPNCVLSVITTIIGISLLEEVPGDIKFHLRCGGFSELFVFAVTFCTTIFYSIEAGICIGCVYSIINIIKHSAKSRIQILARVAGTS----------NFTNLDDYMMNMKRNSLDVEGTEEIEGCMIVRI-----------------------------------------------PEPLTFTNSEDLKQRLDRIERYGSSKIHPGRKSLRSKD---------------------SIKYVIFDLGGMTSIDSSAAQVLEEIITSYKRRNVFIYLVNVS---INDKVRRRLFKAGVAASVERAQANNNENNTSNTFSDAGETYSPYFDSIDAALYEIEKMKIKGNNVPNNDSESFMSNTLFNSSLV-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : : : .. .* .. . :* :.***:*. . : *::.*:: . :::* .::: :* :.. *** :. :.* :** :: *. :. *::..: : : . :. : : :: . : : .: ::* :. **:.::.** ::.. :: * : : : . . : .** : . : . *: : : :. * :* :::*: ** :: * :. :*.: . : *: * . : :: :*:: : : . ::...:. * .*:*:.*:* *:. . * . . : :*. * ::.: . :.::*: : :. :*..**. : : : : : : : : :* .: .: *: :* *:: : : *. : : . :: : ..* . : :. : . ....: : . . . : ::: :::*:. : :* . :.* .: . .. : *.. : : :. * . : :: ::: ", "identical_positions": 61, "similar_positions": 235, "identity": "6.85%" }, { "cls_id": "homologset.agr.MGI:2444596", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6DI86-1", "uniprot_id": "FAKD1_MOUSE", "id": "Q6DI86-1", "name": "FAST kinase domain-containing protein 1, mitochondrial", "aln": "--------------MFRLRSISLLSWRAFPLRPFSCESLITQMQKCTNEEQVFDLIETNTATLSEQQVGCAFNVLWQFQKQKTVLEKNVDHVRNHPQFLTLCSITTNHIPAMSDATLVDVLYSIKQFAVESHHPLIEALVTEAWKRLERFDTNVLSIFSTCLADQHLYFSPLMGKIADIVNRRLETIQDLRALSVLMVSISSLISPCFQERLVIRTELLFDTVNSSKVNIARRILLFLRNVKYSHYPLLERCNQVFIRNMSHLDLESISKILNLYQFLQFHSFEFVEAARGRLAEMTLPSDHPESFVRLFAALGPVARPEIKKQLKSTILLLSEELSSQQALIVLGAMEDMESRNSHLLKKIVSVLYKHLDNYKSIELLKIIQALTFLHFQSKELFMKLRELLLSRLEASVIPSEISVLVSALSMLPHPHLSETAVSRIEAVLPQCDFRELNDLVVYLMRWIQSDLVCLASTTGKQLDLLQKLDQLGRHRLQQSTNLDLLWEELKSLKGEWLHESLVEESIAALLRFMDEIDYSNIAKVASFLSRTNYLNTLLLDRIASVAIQQVEKIHPFSVLAIILPFSILNYDPPQKDEFFGACVQCCNSYLGTLDPGTLVFLGFSLAVLEYFPEDLLKKMFNIEFLARLDSQLEILPSSLSARIQFRLMELNRAVCLECPELQVPWFHDRFCQRQFNKDTGVMNGAQQQIYKMLAEVLGGHQCVKPSALSPYYHTVGFECILDKRKKPLPYESHS-IAPRKSLGMHWDS----RVEPRLPPEAERIAIELLDVRAFCSNIPHLKGKSAMKKRHLEILGYRVIQIPYFEWNSMAMSTKDARMDYLREHLFGEGKS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZFR0-1", "uniprot_id": "D3ZFR0_RAT", "id": "D3ZFR0-1", "name": "", "aln": "--------------MFRLRGVSLLSWRAFPFRPFSCESLIVQMQNCADEEQVFDLIERNKATLSEQQVGCAFNVLWQFQKQKTILEKNVERVRNHPQFLSLCSVTTDHIPAMSDVTLVDVLYSIKQFAVESHHPLIEALVTEGWRRLERFDINVLSIFSTCLADQHLYFSPLMGKIADIVNRKLEAIQDLRALSVLMVSISSLISPCFQERLLTRAELLFDTVDSSKVNIARRILLFLRNVKHSHYPLLERCNQVFIRNVSHLDLESISRILSLYQSLQFHSFEFIEVARGRLAELSLPSDHPESFVRLFAALGPVARPEIRKQLKSTILLLSEELSSQQALTVLGAMEDMESRDSHLIKKIVSVLYRHLDNCKSVELLKIIQALTFLHFQSKELFMKLREVLLSRLEASVTPSEVSVLVSALSMLPYPHLNETALSRTETVLPQCDFRELSDLVVCLMRWIQNDHLCSASTAGKQLDLLQKLDHWGHRRLQQSTSLDLLWEELKSVKGEWLHESLVEESITALQRFMDEIDHSNVAKIASFLSKTNYLSTPLLDRIASVVVEQIKKIHPFSVLAIILPFSILNYDPPQKDEFFGACVQCCNSYLGTLDPGTLVFLGFSMATLEYFPEDLLKKMFNIEFLARLDSQLEILPSSLSARIQFRLMELNRAVCLECPELQVPWFHDRFCQRQFNKDTGVMNGAQQQIYKMLAEVLGGHRYVKPSTLSPYYHTVDFECILDKRKKPLPYESHS-VTPGKSPGVHGDSN-TSRAEPRLPPEAERIAIEFLDVRAFCSNILHLKGKSAMKKRHLEILGYRVIQVPYFEWNSMAMSTKDTRMDYLREQIFGAGRS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q53R41-1", "uniprot_id": "FAKD1_HUMAN", "id": "Q53R41-1", "name": "FAST kinase domain-containing protein 1, mitochondrial", "aln": "MKKTPVFLESLVTNMLRLRAICPFSWRVFQFRPISCEPLIIQMNKCTDEEQMFGFIERNKAILSEKQVGCAFDMLWKLQKQKTSLLKNAEYVRDHPQFLTLHNLATNKFKLMNDDTLVNVLYVTQQFAGEAHDPLVEALVTEAWRRLERFDIKLLSEFSSCLADQHLYFSPLMGKIADIVHRNLETTQDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRNVRYRYQPLLERCNNVFLSNVDHLDLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIPLCNHPASFVKLFVALGPIAGPEEKKQLKSTMLLMSEDLTGEQALAVLGAMGDMESRNSCLIKRVTSVLHKHLDGYKPLELLKITQELTFLHFQRKEFFAKLRELLLSYLKNSFIPTEVSVLVRAISLLPSPHLDEVGISRIEAVLPQCDLNNLSSFATSVLRWIQHDHMYLDNMTAKQLKLLQKLDHYGRQRLQHSNSLDLLRKELKSLKGNTFPESLLEEMIATLQHFMDDINYINVGEIASFISSTDYLSTLLLDRIASVAVQQIEKIHPFTIPAIIRPFSVLNYDPPQRDEFLGTCVQHLNSYLGILDPFILVFLGFSLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQFHLMELNRSVCLECPEFQIPWFHDRFCQ-QYNKGIGGMDGTQQQIFKMLAEVLGGINCVKASVLTPYYHKVDFECILDKRKKPLPYGSHN-IALGQLPEMPWESN-IEIVGSRLPPGAERIALEFLDSKALCRNIPHMKGKSAMKKRHLEILGYRVIQISQFEWNSMALSTKDARMDYLRECIFGEVKSCL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8W7-1", "uniprot_id": "E7F8W7_DANRE", "id": "E7F8W7-1", "name": "", "aln": "--------------MLRLRLFPGRSLRPFHRQAVLQDPVLEHLKACSSEEQVFNVVGRNKAKLSVGHVNCAIGLLWQFQIERPEMLRTLNLIQNHPQFLTLRVLAENKISLMEDCALVDTLYNVLRLKVEHHDTLVQQLVTEAWNRLERLPMGTLSKFAVCLSDMFLQHSPLMGHITQIVSQRLDTIQHAKVLTPLMVSIYALVSPQLRDSIIKRADTLLDQMDPFRFNNPRRVVQFFKNSRYIHKPLLDKCNQLFLQNIDHLDTDAIGIIMGLYHTLQYSSSYFKVAVKQRLMELMDGKTDPDVFTKLFSYLGPIAGQGVREELERTALLLADELNSQQALVVLEAMEDMQCRNLQLINKMESVLYKNLETYRPLEITRITQALVLLHCQNPDILSRLKTKLLHHLQSSVYPFEVTVLIRVLSMLPSRRLDEGVVSRVNAVLPQCSLNNLNTYSIVVAKWIRNDPSYRINTPSRYVQLLQTLNRCGRERLKHFQRLDGVLEELKFMSGEWFEEMLLEKSIVTMQKMIDQISWTNVQELAIYLTRTNYLCTALLDRIASVTVENIDKIHYSDAYITLLPYAILNYDPPMVEEFFDACIQHITPYIGSFDPHLLVLMAHALAMADYFPEEMIREIFSVDFLAKLDAHLETFPESQNLYIRLRLMQLNRAVCLECPEFHVPWFHERYCQQLQKRANSSISPIQQQIHKILGEVLGGINCAKAAVVTPYYYTVDFELVLDRHLHPLPYSEPTRLQISGGGKGHWQSGSAEKERTELPPGARRIGLDFLDSRSFCRNTRHMKGEATMKKRHLEILGYHVLQIPHYEWNSMELSTDDAWKEYLKEKIFTELP---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 303, "similar_positions": 309, "identity": "35.65%" }, { "cls_id": "homologset.agr.MGI:2444600", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JY13-1", "uniprot_id": "A0A0G2JY13_RAT", "id": "A0A0G2JY13-1", "name": "", "aln": "MVFAPGDKPRNELEEVKLQNASKQIVQNAILQAVRQVSQESLRREGRSGDCRARGELGVRELTKKHEKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3UWD5-1", "uniprot_id": "AKAI1_MOUSE", "id": "G3UWD5-1", "name": "A-kinase anchor protein inhibitor 1", "aln": "MVFAPGEKSGKELEEVKLQNTSKQIVQNAILQAMRQVSQESLRREGRPGDSRAWGQLGGCELTKKHEKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CW23-1", "uniprot_id": "AKAI1_HUMAN", "id": "P0CW23-1", "name": "A-kinase anchor protein inhibitor 1", "aln": "MVFAPGEKPGNEPEEVKLQNASKQIVQNAILQAVQQVSQESQRREERISDNRDHIQLGVGELTKKHEKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:*. :* *******:************::****** *** * .* * :** *********", "identical_positions": 50, "similar_positions": 8, "identity": "72.46%" }, { "cls_id": "homologset.agr.MGI:2444608", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BRU4-1", "uniprot_id": "CLC9A_MOUSE", "id": "Q8BRU4-1", "name": "C-type lectin domain family 9 member A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHAEEIYTSLQWDIPT-SEASQKCQSPSKCSG------------AWCVVTMISCVVCMGLLATSIFLGIKFFQVSSLVLEQQERLIQQDT----------------ALVNLTQWQRKYTLEY--CQALLQRSLHSGSDCSPCPHNWIQNGKSCYYVFERWEMWNISKKSCLKEGASLFQID---------------------------------------------------------SKEEMEFIS-SIGKLKGGNKYWVGVFQDGISGS-WFWEDGSSPLSDLLPAERQRSAG---QICGYLKDSTLIS------DKCDSWKYFICEKKAFGSCI---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4AD02-1", "uniprot_id": "CLC9A_RAT", "id": "D4AD02-1", "name": "C-type lectin domain family 9 member A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHEEEIYTSLQWDIPT-SEASQKCPSLSKCPG------------TWCIVTVISCVVCVGLLAASIFLGIKFSQVSSLVMEQRERLIRQDT----------------ALLNLTEWQRNHTLQLKSCQASLQRSLRSGSNCNPCPPNWIQNGKSCYYAFDRWETWNNSKKSCLKEGDSLLQID---------------------------------------------------------SKEEMEFINLSIWKLKGGYEYWVGVFQDGPSGS-WFWEDGSSPLSDLLPTDRQLSAS---QICGYLKDHTLIS------DNCSNWKYFICEKKAFGSCI---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UXN8-1", "uniprot_id": "CLC9A_HUMAN", "id": "Q6UXN8-1", "name": "C-type lectin domain family 9 member A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHEEEIYTSLQWDSPA-PDTYQKCLSSNKCSG------------ACCLVMVISCVFCMGLLTASIFLGVKLLQVSTIAMQQQEKLIQQER----------------ALLNFTEWKRSCALQMKYCQAFMQNSLSSAHNSSPCPNNWIQNRESCYYVSEIWSIWHTSQENCLKEGSTLLQIE---------------------------------------------------------SKEEMDFITGSLRKIKGSYDYWVGLSQDGHSGR-WLWQDGSSPSPGLLPAERSQSAN---QVCGYVKSNSLLS------SNCSTWKYFICEKYALRSSV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7Z4-1", "uniprot_id": "E7F7Z4_DANRE", "id": "E7F7Z4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQTDKLAEDVEGNPDR-VDPYHQQ---GKVAC------------AMFTVLLLFSFLVIGIVTGFNFK-------KSPQEDQNRGLLSDDI----------------TPI----------------------PFQYKSDKGLCSDGWLLYKNTCYLLENVYGTWKSSKSLCLSRGAHLMVVD---------------------------------------------------------SEEELEFISRVVQKWT---DYWIGLKRD-KMGK-WFWVNGDDYHSNLHFWDENQPAHGGMESCVYLKGSDTVNRKLFHDSDCSSQRFHICEHQI--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8L7-1", "uniprot_id": "A1Z8L7_DROME", "id": "A1Z8L7-1", "name": "C-type lectin domain-containing protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQKSIIFLVLPLCLSSSYSAACEGVESDSQCA------------AYCYGVLNPCIASMGNLQRRVEACEAAVAIARIALNDRRLDNFGTS----------------TNLQLENQNTS--------QQLLTHGTAMGRKLEENEIFQQLGSKYYYIEKEEKLNWHDALDKCHKMGGHLASLQ---------------------------------------------------------SQEELDRFNNQLNGLN---RYWIDVTNQFNESE-FVSVTKGSKANFLSWADGEPTKDGECVDIRTFNGKTTMN-----DNSCFANLYFICEKSIEI------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPS1-1", "uniprot_id": "Q9VPS1_DROME", "id": "Q9VPS1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFKYDTYFLYLIVLLDPQGAQENNCPKVSLSERLEKRGEFSLVEFDPLLKFIVKNPHKELLGEIEGLVGHTENKLQPMKSVIPNQSKALLNYL----------------DLHSKLEYLDAALQKAINSLQCSLKNTKVMSTGKPHPEFQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLATPQ---------------------------------------------------------DEDELYLIRKQLEARW----FWLDISNLVDKDQ-YISLATGKEVSYLKWRHGEPKKSS-TANCAYLYAGDYYT------YQCSDRNFFICQAV---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLM0-1", "uniprot_id": "Q9VLM0_DROME", "id": "Q9VLM0-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYKYATCIFSIFALWNFWGVSAKKQDTSTGTN------------ELPKAPMPYYTIENIDMHQQHWFTYNSLRQNGTLWRIGNMEQRLEM----------------RLQSFQNQMETKLRALKQQIEPYMENVKMSNKIKMS-VFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANIL---------------------------------------------------------DEKELNEIFSEETKKK----YWVDINSRANDGASWISTLSGRDVPFLKWKPNLATNIH--NHCVYINSNEMYF------ENCANDNYFACQAEQWA------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PFV8-1", "uniprot_id": "M9PFV8_DROME", "id": "M9PFV8-1", "name": "", "aln": "MCGSHKMWCCQVFILALFAHTIAVEFHGSAARAEINFEGPSPAHSQDTAAPTSRPKRRVYALCPPKFHRVGTDCYSLVDQRSSWLEAHFFCKDKNANLTEPGKHADRKLRLFLQKQDALSGENDPIWLGATYDHHNNRWQWSMSGRNLSTDSFSRTDSAYVQLISNSQPLDNNCAIYDPSLKYRWSARPCSDKLRFICQHKMPKVSGPNRYKIYNRWNATYPNEQANEVVLEILEPRENDRRYHRRVKAEDSDEEMIIPDRRRNNNRRNNHRNRQIKNQNQHPNDVNYQPAQQRQRNRPRTSTVAPTTTQSVSQSNDVLAPSPTPQQMTQYDRKLQRQRERERRRQLRRQERQKLAREQKRERQRRLKEERQRLQREEQQRRQ-RLHHDEPKPQVNPQVKPQVIDELRQRSGEDLDKNQTDEHEQKLRNEQEKKLREEQQKQRDEQEQKDREEQDRLKQEEEQARTHQKELKENQEQQLRELKAKQEREKQERDYQQQKREHELELLKQRQAEADRQHAADEEAEKLRLERIQKQRELEAQQRREREEQRRKQREEQEEQDRQNHAKRLAEEKRLHDLYAERIRLANTEREKQLAEAHEAKRLEELKLQEQLKKQEDERQEQIRREQEEEEKRLELERLEEARRFEEKELKRLHEENQRREEQKLQREREIALREAAEKKLAEEEEMLRKEVAEEERKVKQRLEDEMRQAEEARKAKEAEERAAEEAKAAEQKRRVEAAKKKADEEVKAKLEEKRREYVTRISALSPEDQKKFIEMRKRRKQLKEKKERDQRAKELKRIQQAMRLDDNE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : * : . * . . .: ", "identical_positions": 2, "similar_positions": 10, "identity": "0.25%" }, { "cls_id": "homologset.agr.MGI:2444609", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZ94-1", "uniprot_id": "NLGN3_HUMAN", "id": "Q9NZ94-1", "name": "Neuroligin-3", "aln": "-------------------------------------------------------------------------------MWLRLGPPSLSLS--PKPTVGRSL-CLTLWFLSLALRAS--------------------------------TQAPAPTVNTH-FGKLRGARVPLPS-EILGPVDQYLGVPYAAPPIGEKRFLPP-EPPPSWSGIRNATHFPPVCPQ-NIHTAVPEVMLPVWFTAN----LDIVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDS--GAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTG----DQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLT--LSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLD------TVDMVDCLRQKSAKELVEQDIQPAR-YHVAFGPVIDG-------------DVIPDDPEILMEQGEFLN------------------------------------------YDIMLGVNQGEGLKFVEG---VVDPEDG-VSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWAD-RDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP-----------------------------TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKAN-RFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYN--------LHDMFH----------YTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAG---------------------------------------------PLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKR-RQEPLRQPSPQRGAG------------------------------------------------------------------------------------------------------APELGAAPEEELAALQLGPTHHECEAG-----------------------------------------------------------------------------------------------------------------------------------PPHDTLRLTALPDYTLTLRRSPDDIPLMTP----------------------------NTITMIPNSLVG-----------------------------------------------------------LQTLHPYNTFAAGFNSTGLPHSHSTTRV-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q62889-1", "uniprot_id": "NLGN3_RAT", "id": "Q62889-1", "name": "Neuroligin-3", "aln": "-------------------------------------------------------------------------------MWLQLGLPSLSLS--PTPTVGRSL-CLILWFLSLVLRAS--------------------------------TQAPAPTVNTH-FGKLRGARVPLPS-EILGPVDQYLGVPYAAPPIGEKRFLPP-EPPPSWSGIRNATHFPPVCPQ-NIHTAVPEVMLPVWFTAN----LDIVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDS--GAKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTG----DQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLT--LSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLD------TVDMVDCLRQKSAKELVEQDIQPAR-YHVAFGPVIDG-------------DVIPDDPEILMEQGEFLN------------------------------------------YDIMLGVNQGEGLKFVEG---VVDPEDG-VSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWAD-RDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP-----------------------------TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKAN-RFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYN--------LHDMFH----------YTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAPGSWNGDQDAG---------------------------------------------PLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKR-RQEPLRQPSPQRGTG------------------------------------------------------------------------------------------------------APELGTAPEEELAALQLGPTHHECEAG-----------------------------------------------------------------------------------------------------------------------------------PPHDTLRLTALPDYTLTLRRSPDDIPLMTP----------------------------NTITMIPNSLVG-----------------------------------------------------------LQTLHPYNTFAAGFNSTGLPNSHSTTRV-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYM5-1", "uniprot_id": "NLGN3_MOUSE", "id": "Q8BYM5-1", "name": "Neuroligin-3", "aln": "-------------------------------------------------------------------------------MWLQ---PSLSLS--PTPTVGRSL-CLTLGFLSLVLRAS--------------------------------TQAPAPTVNTH-FGKLRGARVPLPS-EILGPVDQYLGVPYAAPPIGEKRFLPP-EPPPSWSGIRNATHFPPVCPQ-NIHTAVPEVMLPVWFTAN----LDIVATYIQEPNEDCLYLNVYVPTED--------------------GSGAKKQGEDLADNDGDEDEDIRDS--GAKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTG----DQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLT--LSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLD------TVDMVDCLRQKSAKELVEQDIQPAR-YHVAFGPVIDG-------------DVIPDDPEILMEQGEFLN------------------------------------------YDIMLGVNQGEGLKFVEG---VVDPEDG-VSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWAD-RDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP-----------------------------TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKAN-RFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYN--------LHDMFH----------YTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAPGSWNGDQDAG---------------------------------------------PLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKR-RQEPLRQPSPQRGTG------------------------------------------------------------------------------------------------------APELGTAPEEELAALQLGPTHHECEAG-----------------------------------------------------------------------------------------------------------------------------------PPHDTLRLTALPDYTLTLRRSPDDIPLMTP----------------------------NTITMIPNSLVG-----------------------------------------------------------LQTLHPYNTFAAGFNSTGLPHSHSTTRV-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2BHL9-1", "uniprot_id": "A2BHL9_DANRE", "id": "A2BHL9-1", "name": "", "aln": "------------------------------------------------------------------------------MMIYTQSAAHLALTRLPCRPLNSALRWLLVWLMWSVSVAS--------------------------------TLTYQPTVNTA-LGRLRGMRVAVAT-EGLGPVDQYLGVPYAAPPVGEKRFMPP-DAPSAWSGVRNATRFPPVCPQ-TVRNAVPDIMMPVWATYN----MDTVATYLQEQSEDCLYMNIYVPTQS----------------------GTKRTGDMSADTERTEDDGLRDSRDDPRPVMLFIHGGSYMEGTGNIMDGSVLASYGNVIVITLNYRVGILGFLSTG----DQAAKGNYGLLDQIQALRWINKNIGYFGGDPGRVTVFGSGIGASCVSLLT--LSHHSEGLFHRAIIQSGSALSSWSVNYQPVKYTRLLAERVGCNVLD------TQDLVLCMQKRSYRELVEQEIQPAR-FHVAFGPVIDG-------------DLIPDDPEVLMEQGEFLN------------------------------------------YDIMLGVNQGEGFRFVEG---VVEPEEGGVSGSDFDFTVSDFVDSLYGYPEGKDTLRETIKFMYTDWAD-RDNPETRRKTLVAMFTDHQWVEPAVVTADLHARYGSP-----------------------------TFFYAFYHHCQSPMKPPWADSAHGDELPYVFGVPLIGPTELFPCNFSRNDIMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKAN-RFEEVTWAKYGPHDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYN--------LHDMFH----------YTSTTTRVPPLLTTHSSHS---------ATPRPGGNKARTSGKQPP--QSTARSG---------------------------------------------PLVIANPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRSRQDTPPQPAPQRQTP------------------------------------------------------------------------------------------------------PIDLNYAPTS-----ISGGNQEELSLC-----------------------------------------------------------------------------------------------------------------------------------DPLRLTPASSPRDYALTLRRSPDDIPLMTPSSVAMTPNSGTMTPNTVTLTPNSVTMTPNTITMSPNSLMG-----------------------------------------------------------YPSMHPYNTFTHGYNSTTLPHPHSTTRV-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIC6-1", "uniprot_id": "Q9VIC6_DROME", "id": "Q9VIC6-1", "name": "", "aln": "MVMLLSKRQLPPSAATRTRRKVPPTRRRSTWALSSLLALVVLDICIARCLAAGISYSSNSGNLSTSQKSPSSANNGGLVLIGSSSATSSSVPSLSLTSSSSAGLSSPGSSSSSSSSSTSTSGSNSNRSSRPTSNNSNSNSNYSPNHDQLPAQLSSRIINTR-NGAISGVIVQLDG-RHLDPVEAYRGIPYASPPVGNLRFMPP-VSAAMWSGVKKADRFSPVCPQ-RLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAG----SSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYS-KLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCAS----DLP-HAHLMKCLREKTLDQLLSVPIRPPE-FGFAFGPSIDGVVIDGG-------DYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFN----SGDVQYG-IEADRRSRILKAYVRNTYTFHLN--EIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHR-----------------------------NSYLYVFDYQTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGS--RQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIPDLHKPGGDNVPAAHHQLHDDDDEDNNIPSDASVKPLNPPYISRAANAAAMANFTIFTNQVFSLLNLSSPSSSLQRNGTRYGGG-----KIYPDDMMD------GDHAGG--------AASASQD-------SDGFAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLSEPRPQTKLKRQ-------------------------ENGQMPNNICGDLETLTIHA---------------------KSDPATILSHHHAMQHHQLP------------------PPEFADIPHRAPPPPKHMKSLQDP------------------------------GGGGSVSG--AVGVSG--------VVQMPPP---------------HALQVMGNQCGTLTKKS------------------------------CMKQTQ----AQAQQHSPAQQQQQQQQQQQQ-------HVVT--HQQHLQN---------------HHNQSMTTVLTTAGG-----LVVPTPP------TVPVIVASTTQHQQH--------------------------QQQHQQQQHQQQQQQQQQQHPLMDELRV-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A6H2EDS1-1", "uniprot_id": "A0A6H2EDS1_DROME", "id": "A0A6H2EDS1-1", "name": "", "aln": "--------------------------------------------------------------MGESQ----------LLLLLR---------LLLLPTVLISWMHCAGASTADIYKG---------------------------------ARLGHRIVQTR-YGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPT-RAPAPWDGIRISDKYSPVCPQ-RLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEK-------------------------------------------KLPVIVFIHGESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRG-LFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRH-HEQIVDCLRDVPLEDLYLADIQAPN-FLTSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFS----AHDIQNG-FEGERRDKIIRTYVRNAYNYHLN--EIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKDGDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLRLIPELHRAGMEDVIARHNLFRNHDDMD---LYEGPVKP-DPFGISTAAGASGSSSSSSSSSRLLLVDEQLMMKKGRGLNGSAYLNGILGVTTVEPNNMYTTCIPIGGNYSSSGGVFAPTTLANASSDTLASGFEAAGYAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLEVKTLQKQYQQRSLHQQV-----PYPPEPIKHAHYHMGHSQSSANVIVDVESHQDQAGQAAMLLQAAAAAAAAAANDVKPPPPHICSNTGMQQQQQVGGGSGGALNNGGIEGSKVTTDNLGNVTYSTSSKQQQQHQQQQQQQQREHMQIKGMTGTQTFGRSGSGSGGGAGGGAGSASGGASVVVSGSSVSYNPGMMTLPKSGGLHHAATLNYARNTTALNMSGGGTALVDSRGNVLLTSTAVGPGMAGTGAGGGSSGGGGGGDCMTLPRNLGLAAAGRHNPTTELQQYQQQQQSSKHQSNGAVLTGMQSHHIRGPRPPLRTASSTTTNSSSNNSAMGVAVGVGGGVGNMLLDQTPSGGSSSSGVSSAPSSSKGHHTHSHSHAAHLVHSHGDGLVLTSASPVGGQQQQHPQQHQHPQQQQQVPQAAMDEMREFYAPKQPDDDGQLNGTPVDADAATQVVGAGRTGGMGAPPISASDHKQRQLKKLRFKREIHALALEGGDVARGYCSCDEQWTNSSSPTSTTTSATMSPTLPAGGSAGDAGRHATGNGPGNSSAGSSGIVKMAAAPGKRSERLKQQHHVRFSDEKNFSD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIC7-1", "uniprot_id": "Q9VIC7_DROME", "id": "Q9VIC7-1", "name": "", "aln": "MKFRLAAFWLFLLTVGGNHKLLSHVSPMGVAAEKQPLHKGNELENAMKLREAPKQSRVIGDITTTIQPDSDPGRSIGHQALRRAKAPPPSLELHFRQNLNKLFAGDETTHVGHTNATDNTTAAVLATDEGSSEHEPSTTHHPERRHVVPDKLQYTQEIQVK-QGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPP-GAPLPWQGLKIARHLPPVCPQ-KLPDLSPHGSENMSRARHK--HLSRLLPYLRTESEDCLYLNLYVPHEEPQSTP------------------------------------------KQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPS---IDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLM--VSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQ-FSTSLGPIVDG-------------HVIPNQPYKVMGHYTEHFSR----------------------------------------YDLLFGITESESYHTLA----ALALEEG-LRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRR-----------------------------NYMYVFGHNSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKG-IFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQLQKPGQEVITGHMSKYGPRDHGAEDPVRTLKLLLQEPSLAGPTQSGESTETAAENMYNAPPTFGHVHKMQG------------------------GSDFEDLVTSTNSLESGEDHPQAPPETVAKSEATMQLLIALITIIIVLNLLIYGTFLLRQRRRRAKALPFPAPKLGGTILSYDGANDEELKRCSKSRDGDDSFVLEMTRKSNTYEAIKTGQRSLSCSTVDTHTKVCEWMSSQEAPKSGSFNTATPPPQPILSDGRLIICQDIEVADAALLIPQHMHEPQHYEMLLQRQHSALTEPSDE---------------------------------------------------ILQQQYPLRNHSHSHSDPVDMILAADEQVTSFVHADDVDIN--------------------------------VTSRDDSDGLEVIPLTSAQQLELLRQRNYPKVLPTEQDLINSSYKRNSLPPQNFNAPLPPPRTISNTLGRRRRDSSNITTSPLQVARDCGGEDEDLKEPQITQNTLIVGPIVPK--------------SPASSLKRVKRMPESSAMTALSGSFQSFEAVPPAHETTPPQGGERTECIYAIRPSPGSCSWAAPNGDLYAQPMKSSSRNSLIPRPTKPAESQSQATPAGPAGESLGSTGMATASRIPQLQRQASGKDLQARTATDNTANPLGCQPRTDSTISSGSSASYASTTDSSSSSSTGTVRTELQQFQPAPGRSITTNI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W1B3-1", "uniprot_id": "Q9W1B3_DROME", "id": "Q9W1B3-1", "name": "Carboxylesterase type B domain-containing protein", "aln": "---------------------------------------------------------------------------------------------MDCRANFLAYLAVFLHLVSDYCFVP-------------------------------VQCVDAPFIHIPGNGVISGTYLKMFR---TQNIKAYLGIRYAHA----RRFQPPDIELTPWKGIFNATVFQPDCWQNAMPSVGKETEQILKIIQSD----SSAQDAERKYEENCLYLNVFVPDGLPEING--------------------------------------------YAVVVWIHSGDFSTGSPADVEPFQLVFKQKVIVVTFSYRLNIFGFFTTD----DGEAQGNYGLMDQSAALYWVKKNINFFGGDSNRITLMGHDAGAVSVALHMT-SGEWSKGGFHKAIIMSGNPLSTVKMPYEYEGSLDQVSSTFACPRRP------TSMFIQCLKRIDAKRLSENLPQVSWGPVVDFGLSNTS------------YPFIENQPEILFKKGSYHR------------------------------------------VPVIIGVTDMEEVLTLFKDNLDTDISPSDLEGFYTDIAVTDMHKLVRNYEWCSNYELISDAINFMYANDSDTDAKKANKHIISAHTEKFYITPMQTFADLISNDSQVY----------------------------SYLFRMRPRSVLQDLPSWISVPKYFDQIFVWGNPYMTN----SVDWKSTDKKIADIIMTLWANFAKTSNPTK---------------SNVYVKWNAMTPNNDSVLLIDESFNTDNLLNNQRINFWRSLYP----------------------------------------------------------KILVFSADCCN---------------------------------------------------------------STFSGSGLVIATSVPILCTLSIIVNIF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * : * . :. : *: ** . ** *. *.*: : * * * : . . . .*:***:*:: * .*::::*. .: .: : * :::*:*..**:.::**: .. .**.*:* ** *:.:** **** :*: * . ** .: *::**: **. : : :: . * :: *:: : . :* . : . . :: *: * . . . . . : .. : :: : * : : ::: : . . : :::* * . ::. : :: :* *:**.:*.:*. : * . * :. . : :* * : :.: : .: : ", "identical_positions": 68, "similar_positions": 133, "identity": "4.21%" }, { "cls_id": "homologset.agr.MGI:2444611", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TMY7-1", "uniprot_id": "IPO8_MOUSE", "id": "Q7TMY7-1", "name": "Importin-8", "aln": "-MDLNRIIQALKGTIDPK--LRIAAETELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEVIFPFNIHENDRQQIRDNIVEGIIRSPDLVR---VQLTMCLRVIIRHDFPG-HWPAVVDKIDYYLQSPNSGSWLGSLLCLYQLVKTYEYKKAEEREPLLAAMQIFLPRIQQQILQLLPDASHYS-----VLLQKQILKIFYALVQYALPLQLVNHQTMTTWMEIFRTIIDRTVPPETLQIDEDD-RPELVWWKCKKWALHIVARLFERYGSPGNVT-KEYFEFSEFFLKTYAVGIQQVLLKILDQYRQ-KEYIAPRVLQQAFNYLNQGVVHAVTWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKR-KEVLPKMMAFCYQILTDPNFDPR--------KKDGALHVIGSLAEILLKK-SLFKDQIELFLQNHVFPLLMSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIED-EEMPVKVEAALALQSLISNQAQAKEHMKPYVRFIMQELLHIVRETENDDVTNVIQKLICEYSQDVASIAVDTTQHLAEIFG---------------KVLQSDEYEEIEDKTVMAMGILHTIDTILTVVEDHPEIIQQLENICLRIIDLVLQKHVI---EFYEEILSLAYN--LTCHTISPQMWQLLGILYEVFQQD---CFEYFTDMMPLLHNYVTVDTNALLSNPKHLEVLFTMCRKVLCGEAG--EDAECYAAKLLEVIILQCKGRGIDQCIPLFIQLVLERLTRGVKTSELRTMCLQVAIAALYYSPELLFHTLEQVQLPHNPGPVTSQFINQWMNDTDYFLGHHDRKMCIIGLSVLLEL-QNRPPAVDAVAAQILPSILFLFLGLKQVCATRQTVNRENHSKAEK--------VDIEENEEISSEEEEETSVSAQAMQSQIGRSE--EEDDDD------WDEEV--LEETALEGFSTPLDLD---NSVDEYQFFTQALLTVQNRDAAWYQLLVAPLSEDQKRKLQEVYTLAEHRRTLAAGQFHI--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K6J6-1", "uniprot_id": "A0A0G2K6J6_RAT", "id": "A0A0G2K6J6-1", "name": "", "aln": "-MDLNRIIQALKGTIDPK--LRIAAETELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEVIFPFNIHENDRQQIRDNIVEGIIRSPDLVR---VQLTMCLRVIIRHDFPG-HWPAVVDKIDYYLKSPNSGNWLGSLLCLYQLVKTYEYKKAEEREPLLAAMQIFLPRIQQQILQLLPDASHYS-----VLLQKQILKIFYALVQYALPLQLVNHQTMTTWMEIFRTIIDRTVPPETLQIDEDD-RPELVWWKCKKWALHIVTRLFERYGSPGNVT-KEYFEFSEFFLKTYAVGIQQVLLKILDQYRQ-KEYIAPRVLQQALNYLNQGVVHAVTWKQMKPHMQNISEDVIFSVMCYKDEDEELWQEDPYEYIRVKFDIFEDYASPTTAAQTLLYTAAKKR-KEVLPKMMAFCYQILTDPNFDPR--------KKDGALHVIGSLAEILLKK-SLFKDQIELFLQNHVFPLILSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIED-LEMPVKVEAALALQSLISNQTQAKEYMKPYVRFIMQELLHIVKETESDDVTNVIQKLICEYSHDMASIAVDITQHLAEIFG---------------KVLQSDEYEEIEDKTVMAMGILHTIDTILTVVEDHPEIIQQLENICLRIIDLVLQKHVI---EFYEEILSLAYN--LTCHAISPQMWQLLGILFEVFQQD---CFEYFTDMMPLLHNYVTVDTNALLSNPKHLEVLFTMCRKVLCGESG--EDAECYAAKLLEVIILQCKGRGIDQCIPLFIQLVLERLTRGVKTSELRTMCLQVAIAALYYSPELLFHTLERVQLPHNPGPVTSQFINQWMSDTDYFLGHHDRKMCIIGLSVLLEL-QNRPPAVDAVAAQILPSILFLFLGLKQVCATRQTVNRENHSKAEK--------ADIEENEEISSEEEEETSVNAQAMQSQICRGE--EEEDDD------WDEEV--VEETALEGFSTPLDLD---NSVDEYQFFTQALLTVQNRDAAWYQLLVAPLSEDQKRKLQEVYTLAEHRRTLAG-QFHI--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15397-1", "uniprot_id": "IPO8_HUMAN", "id": "O15397-1", "name": "Importin-8", "aln": "-MDLNRIIQALKGTIDPK--LRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVR---VQLTMCLRAIIKHDFPG-HWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYS-----VLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDD-RPELVWWKCKKWALHIVARLFERYGSPGNVT-KEYFEFSEFFLKTYAVGIQQVLLKILDQYRQ-KEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKR-KEVLPKMMAFCYQILTDPNFDPR--------KKDGALHVIGSLAEILLKK-SLFKDQMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIED-KEMPVKVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFG---------------KVLQSDEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVI---EFYEEILSLAYS--LTCHSISPQMWQLLGILYEVFQQD---CFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFTMCRKVLCGDAG--EDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIGLSILLEL-QNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEK--------ADMEENEEISSDEEE-TNVTAQAMQSNNGRGEDEEEEDDD------WDEEV--LEETALEGFSTPLDLD---NSVDEYQFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFENKGVLSAFNFGTVPSNN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8RMT5-1", "uniprot_id": "A0A2R8RMT5_DANRE", "id": "A0A2R8RMT5-1", "name": "", "aln": "-MDPNRIIQALKGTIDPN--LRLAAENELNQSYKIINFAPTLLQIIVSEQVEFPVRQAAAIYLKNMVSQYWQDREPTLGEVVFPFNIHENDRGQIRENMVEAIIRCPESIR---AQLTVCLRAIIKHDFPG-RWTGVVDKINLYLQSQNSGSWYGSLLALYQLVKNYEFKKAEERDPLLAAMQIFLPRLQQLITQLLSDATFIS-----VLIQKQILKIFHALVQYSFPLQLINNTVMTHWMEILRTVVDRDVPAETLEADEDD-RPELIWWKCKKWALHILTRIFERYGSPGNVT-KEYVEFADFFLKTYALGIQQVLLKVMEQHRQ-RQYVSPRVLQQTLSFMTQGVSHSLTWRQMKPHMQTITHELVFPLMCYKDEDERLWQEDPYEYIRMKFNVYDDHVSPATAAQTLLCTAARKR-KEVLPQMMEFCHQILVDPSADPR--------RTDGALHVIGTLAQPLLKK-RVYRDQMELMLQNYVFPLLNSNLAYLRARSCWVLHSFSPLKFHNELVLRNAVELVKHNLVED-KEMPVKVEAAIALQTLVRNQEQAKVYIRPFIRPVMQELLHIIKETENDDLTGVIQKMICEYSEEVTVIAVDMTQNLAEIFS---------------KILQSEEYEESEDKTVMALGILSTIDTILTVMGDRKEISQQLEGICLQVIGLVLQKPIIGMAEFYEEILSLAFG--LTCYCISPQMWQLLGVLYDVFQHD---CFDYFTDMMPLLHNYVTVDTNMLLSDPKYLEVIYTMCKKVLTSDAG--EDPECHAAKLLEVIILQCRGRGIDQCIPLFVEAVLERLTRGVKSSELRTMCLQVVIAALYYNPTLLIHTLENIRFPHSPEPITAQFINQWMNDTEFFLGLHDRKMCVIGLSILMEL-PSRPAVLEEVVGQIVPSVLLLFLGLKHIYASRVLNKPEQFGRAQG--------SEEEENEEIPSDEDEVGEKGVALQPSVAPTGNDNEDDDDEDD-DEYWDDEG--LEGTPLEEYSTPLDCD---NGEDEYQFFTASLLRVQSSDAGWYQSLTSPLNEDQRKQLQEIYNLAQQRRSTGVKGL----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSD6-1", "uniprot_id": "Q9VSD6_DROME", "id": "Q9VSD6-1", "name": "", "aln": "-MEAQKLTELLRATIDPNPEQRKAAEDQLAQIHKIIGFVPTILQIVMQTTVEQPVRQAGAVYLKNLINSSWSDHEAKPGEP-IPFSIHEQDRAMIRGAIVDAIVHAPELIR---VQLSVCVNHIIKSDFPG-RWPQVVDSISIYLQNQDVNGWNGALVTMYQLVKTYEYKRHEERTPLNEAMNLLLPMIYQLMVRLLAEQSEQS-----VLLQKQILKIYYALTQYTLPLDLITKEIFSQWMEICRQVADRAVP-DSSHLDDDE-RTEFPYWKTKKWALHIMVRMFERYGSPSNVVSEKYQKFAEWYLPTFSQGVLEVLLKILDQYRN-RVYVSPRVLTDVLNYLKNAVSHAYTWKLIKPHMVAVIQDVIFPIMSFTDSDQELWESDPYEYIRLKFDIFEDYATPVPAAQSLLHSMCKKR-KGILPKAMATIMQIITSPNADNK--------QKDGALHMIGTLADVLLKK-ASYRDQVESMLTTYVFPEFQNPAGHMRARACWVLHYFCDVQIKNPQVLAEIMRLTTNALLTD-KELPVKVEAAIGLQMFISSQDEAPQYVEAQIKEITKELLTIIRETENEDLTNVMQKIVCTFTEQLLPVATEICQHLATTFS---------------QVLESE--EGSDEKAITAMSLLNTIETLLSVMEEHPDVLLNLHPIVINVVGHIFQHNIT---DFYEETFSLVYD--LTAKAISPEMWQMLELIYQVFKKD---GIDYFIDIMPALHNYVTVDTPAFLSNPNRLLAILDMCKTMLTSSPG--EDPECHAAKLMEVIILQCKG-QIDSVIHMFVELALSRLTREVQSSELRTMCLQVVIAALYYNPQLLLSILDKMSQQNN-DSISAHFIKQWLHDTDCFLGIHDRKLCVLGLCTLISLGEAKPQVLSEVAGKIVPALILLFDGLKRAYESRAQEEEEDEEEEDGDDCEEALSSDEDDMDEMAPDYLDKLAEFAKTKGNESGFEVKAEIKDDDADSDGDAEESVGDLNETGLESFTTPIDDEENESAIDEYWTFKEVITALSAQDQAWYALLTSNLTPEQAKALQEVVVTADQRK-AAKESKLIEKQGGFAFPQTAVPTSFKFGS-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P46970-1", "uniprot_id": "NMD5_YEAST", "id": "P46970-1", "name": "Nonsense-mediated mRNA decay protein 5", "aln": "-MDITELLQCFACTLDHNAAVRTNAETHLKNASKVPGFLGACLDIIAADEVPENIKLSASLYFKNKITYGWSAGARQGSNELLDSHVDPDEKPVVKDMLIKTMVSVSKTSPRCIRVLKSALTVIISEDYPSKKWGNLLPNSLELLANEDITVTYVGLLCLAEIFRTYRWKNNDERQDLEELILNYFPALLNYGANVLFQDGKYMNNEQIGELVKLIIKIYKFVSYHDLPFTLQRSESFTPWACFFVSIIQQPLPQEVLAISDIEVRSKNPWVKCKKWALANLYRLFQRYASTSLTRKFQYDEFKQMYCEEFLTQFLQVVFDQIEKWGTGQLWLSDECLYYILNFVEQCVVQKTTWKLVGPHYNVILQHVIFPLLKPTAETLEAFDNDPQEYINRNMDFWDVGYSPDLAALALLTTCVTKRGKTTLQPTLEFMVSTLQSAVGDYNNIMLDNALQIESCLRIFSSIIDRLITKDSPFASEMEKFILTYVLPFFKSQYGFLQSRVCDICSKLGSMDFKDPVITSTIYEGVMNCLNNSSNSLPVELTAALALQTFISD-DQFNMKLSEHVVPTMQKLLSLSNDFESDVISGVMQDFVEQFAEQLQPFGVELMNTLVQQFLKLAIDLHETSNLDPDSFTNVDSIPDESDKQMAALGILSTTISILLSFENSPEILKNLEQSFYPAAEFILKNDIE---DFYRECCEFVENSTFLLRDITPISWKILELIGECNRKPDSMVSYYLSDFMLALNNILIYGRNELKKNEFYTKIIFEIYQKAVTAEDNSLDDLRVVFDLSQELVLALDDSLPQQYRERLLADVVGSILTQ---KNELKTNVVFSVTAFNVVISNMITEPLITLQYLKQQGCLEIFFQTWITDYIPNYKRCYDIKLSVLALLKIILKLESNDYSVLNLEN-LVPQLGSIVTQLASRLPTALRQLANQRKEFSS--------SGFEEDTKWDENFLDVGDDDENDDEGDLTEKYLELIKNRADS----LDFVDGYDAKETFDDLEEDPLTGSILDTVDVYKVFKESIANLQHVDSNRYQGILRHLTPADQELFMGIMNA----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04175-1", "uniprot_id": "SXM1_YEAST", "id": "Q04175-1", "name": "Importin beta SMX1", "aln": "MVQEQAILSCIEQTMVADAKIIKEAEQQLFEFQKQPGFTSFLLNIVSDDNFALNVRLSSAIYLKNKIHRSWDTKRED--------GIKADEKLSIKERLIETLVKNCENNH-----IRPILTETINGILVGQEDWDLAPIIKNLLSSGDASYIYPGLLLLFQLCKAHRWDMVGSRDYIDSVIEELFPIVEGIASNIGSQTDYRS-----NEILYLILKSFKYACLNNLPQYFSQPERIMSWVQLHLYLCSKPLPVEVMELDPAD-RSLDKRVKVNKWGFGNLNRFLQRYN---KITKAITKEFIDYIFNTIVPIILREFFKDIEAWGNNSLWLSDSSLYFLISFLEKCVTIDQLYPLIEPHLQIIFENVIFPCLCANEQSIELLEDDQEEYTRRYFDINREGSTPDAASADFIFLIGSKR-PEKLNNILPFINDIFTRFDANSSDIN--MAFKEEGALRTLSNLFSFIDEP-----SVLENIFGHFIVPLLSQDKYMFLVARSLETIALYSEEFKDMNILSQLFELTYTNFLNS-NVLPVQIEAADAIKCLIVSNPQIHPAVSAHVPGMMEKLLKLSKIFEIDILSEVMEALVERFSDELSPFAKDLASNLVEQFLR--------IAQALVENPSETYSASDQEQEIQASGLLQTMTTMVMSMNKVP-LIESLAPVVKFVVLHAQISFIT---EAVDLLDALTISSHLLYNQIAPPIWELLHDILDSFQTY---AMDYFEAYSIFFETIVMTG---FPQDQTYVQPLLEILSAKLESEVD--YDIEHVMQILMYFALSMRDIPLFSKAIKVSTNDELG---------------LDSKCIVKLGLANLFAKPIETLQIMENEGFTINFFTNWFNEKFYSVFAIKLQVLVILTLLKMPEVPNSVSPLLNNLTNKLVELTLSLPKAIRNRDAVTEGKSLEGDLTPEE---------EEEYFIECDDDMKETVLDQIN------------------------------------------------------VFQEVHTFFKNLQNEDAGKYEKIINYLDESKRDSLQVILEFVSQH------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . : *: . ** .* : * .* * *: . :: :.::*:** : * :. ::: :: ::. :: . : : * . . : * . . .*: : :: : :.:. .* : : :* : .: : : *:* : :* : : * : : .: :* : . : *. * :**.: : *:::** :* : . . .:. :: ::: * :.:: : * : : ** : ..::*. : . . . :.* ** . ::. :* *: :: ** * : . : : : :..*: :..: . : . :* :: .:.* : . : . : .::: . . : . :**:: ** .:: :: . : : : ::** : . * : :: *:: :: ::.:: .. : . *. * . . .:: : * .:* * ::: . . : .* : : :. . : *:* *::* : : : *: :.. : . : .: : : : .. . * . . : . : : : . :: : : .. * . : :: * : : : :: : : : . : : : : : . : :. * * : * . : : ", "identical_positions": 71, "similar_positions": 269, "identity": "6.4%" }, { "cls_id": "homologset.agr.MGI:2444612", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LJZ7-1", "uniprot_id": "A0ABK0LJZ7_RAT", "id": "A0ABK0LJZ7-1", "name": "", "aln": "MLPTRKGTEAHDWHLDMQLTSKVVLSAAALLLVTVAYKLYKSRPAPAPHAGRKKERHKAENETEGLGQPAFQEAPPGTLPRGPRRRKASKGAGSPLDYSLEDPGDSYILDTPRS---EEPTRKGSDESQDRQRPDSQQVPPPCGGQEAGTAVRGKPNPPHPLHSGCEPTSSPARLIPGVGGSCVGDNLSPWPDSRPLEETGSGDPEAPNCWTDPTLVNG-DMNQSWIFTHMTGVSRGEAGALQAAANMGLATQQQEGATSASHTFSSVARIRMEENVIQKAEG--PELKGRIYDYFVESTSKAV--SRPVPCAAALADAAPSPGPGPEPLVTGAATRDQADNTAGG-TLQVASPQPVPSPSAPGFGRKVSLLQIAENPELQLQPEGFRMPLPAHLDQSAQLGSDCSHGEPHVQLVAGTNFFHIPLTPASALDVRLDLGNCYEMLTLAKRQGLEALKEAAYKVLSDNYLQVLRSTDIYGGLSGAERELILQRRFRGHKCLVVADMCPQEDSGRLCCYDNVQDAWHPLAQLPLEAMSRGCALCSLFNYLFVVSGCQGPAGQPSNRVFCYNPLTAIWSEVCPLNQARPHCRLVALEGYLYAIGGECLNTVERYDPRLDRWTFAPPLPNDTFALAHTATVCANEIFVTGGSLRYLLLRFSAQEQRWWAGPTAGSKDRTAEMVAVNGFLYRFDLNRSLGISVYRCNASTRLWYECATYRLPYPDAFQCAVVDDRIYCVGRRRTLCFLADHISPRFVPNELQGFPAARGTLLPAVLTLPVPDVPQTPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2APT9-1", "uniprot_id": "KLD7A_MOUSE", "id": "A2APT9-1", "name": "Kelch domain-containing protein 7A", "aln": "MLPTGEGAEGQDWHLDMQLPSKVVLSAAALLLVTAAYKLYKSRPAPVGQAGRNNKDHKAENETEALGQLAFQEAPPGTLPRGRRRRKASKGAGTSLDYSLVDPEDPCILDISRS---EEATRKGSDESQGRQCPDSQQVPPPCGGQEAGTDVRGKPNPPHLPHSGCEPTSSSGRLIPGVGGSCVGDKLSPWPDSRPPEETGSGDLEAPNGWTDLTLVNG-DMNQSWIFTHMTGVSRGEAGVLQAAADMGLATQQQEGATNASHTFSSVARIRMEENIIQKAEG--PGLKGRVYDYFVESTSKAD--SRPVPCPAALAD-APSPGPGPEPLVTGAASRDEAANTAGGGASEAASPQPVASPSAPGFSRKVSLLQIAENPELQLQPEGFRMPLPAHLDQRAQLSSACSHGEPHVQLVAGTNFFHIPLTPASALDVRLDLGNCYEMLTLAKRQGLETLKEAAYKVLSDNYLQVLRSPDIYGGLSGAERELILQRRFRGHKRLVVADMCPQDDSGRLCCYDNVQDAWHPLAQLPPEAMSRGCALCTLFNYLFVVSGCQEPGGQPSNRVFCYNPLTAIWSEVCPLNQARPHCRLVALEGHLYAIGGECLNTVERYDPRLDRWTFAPPLPNDTFALAHTATVCANEIFVTGGSLRYLLLRFSTQEQRWWAGPTGGSKDRTAEMVAVNGFLYRFDLNRSLGISVYRCSASTRLWYECATYRLPYPDAFQCAVVDDHIYCVGRRRMLCFLADHISPRFVSKELKGFPSARGTLLPAVLTLPVPDVPQTPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VTJ3-1", "uniprot_id": "KLD7A_HUMAN", "id": "Q5VTJ3-1", "name": "Kelch domain-containing protein 7A", "aln": "MFPR--GAEAQDWHLDMQLTGKVVLSAAALLLVTVAYRLYKSRPAPAQRWGGNGQ-AEAKEEAEGSGQPAVQEASPGVLLRGPRRRRSSKRAEAPQGCSCENPRGPYVLVTGATSTDRKPQRKGSGEERGGQGSDSEQVPPCCPSQETRTAVGSNPDPPHFPRLGSEPKSSPAGLIAAADGSCAGGEPSPWQDSKPREHPGLGQLEPPHCHYVAPLQGSSDMNQSWVFTRVIGVSREEAGALEAASDVDLTLHQQEGAPNSSYTFSSIARVRMEEHFIQKAEGVEPRLKGKVYDYYVESTSQAIFQGRLAPRTAALTE-VPSPRPPPGSLGTGAASGGQAGDTKGA-AERAASPQTGPWPSTRGFSRKESLLQIAENPELQLQPDGFRLPAPPCPDPGALPGLGRSSREPHVQPVAGTNFFHIPLTPASAPQVRLDLGNCYEVLTLAKRQNLEALKEAAYKVMSENYLQVLRSPDIYGCLSGAERELILQRRLRGRQYLVVADVCPKEDSGGLCCYDDEQDVWRPLARMPPEAVSRGCAICSLFNYLFVVSGCQGPGHQPSSRVFCYNPLTGIWSEVCPLNQARPHCRLVALDGHLYAIGGECLNSVERYDPRLDRWDFAPPLPSDTFALAHTATVRAKEIFVTGGSLRFLLFRFSAQEQRWWAGPTGGSKDRTAEMVAVNGFLYRFDLNRSLGIAVYRCSASTRLWYECATYRTPYPDAFQCAVVDNLIYCVGRRSTLCFLADSVSPRFVPKELRSFPAPQGTLLPTVLTLPTPDLPQTRV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* *:*.:********..*************.**:********. : * : : :*::*:*. ** *.***.**.* ** ***::** * :. . * :* .. :* : .:. ****.*.:. * .**:**** * .**: * * .:*:*** : *.**.**.. **....***.*.: *** **:* *..* *: *.*: .* .. ******:**:: **** ***.*:**:::.*: :*****..:*:****:**:****:.****** * ***::***:*****:* .* .* .***:: .*** * * .* ****: .:* :* *. : ..****. . **: **.** ***************:***:* *. * * . * ***** **************** :**********:*******.**:********:*:********.**** *************:**:: *****:**::*** *****: **.*:***::* **:*****:*:************ *. ***.*********.********************:*:**********:*********** ******.*********** *:**********:**:***:**********.***************************:****.************* ************: ******* ****** :*****.:**:.**:.:*****:*****.**:*** *", "identical_positions": 518, "similar_positions": 158, "identity": "66.24%" }, { "cls_id": "homologset.agr.MGI:2444615", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VD33-1", "uniprot_id": "SGTB_MOUSE", "id": "Q8VD33-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "aln": "--------------MSSVKPLVYAVIRFLREQSQMDAYTSDEQESLEVAIQCLETVFKISPEDT-------------HLAVSQPLTEMFTNSVCKNDIRPLSNSVP------------------EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPEND------SYKSNLKIAEQKL--------------REVSSPTGTG--------LSFDMASLINNPAFITMAASLMQNPQVQQLMSG--MMTN----AIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRSRSFSSSADEHS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80W98-1", "uniprot_id": "SGTB_RAT", "id": "Q80W98-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "aln": "--------------MSSVKPLVYAVIRFLREQSQMDAYTSDEQESLEVAIQCLETVFKISPEDT-------------HLAVSQPLTEMFTNSVCKNDIRPLSNSVP------------------EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLSHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTAMNKFEEAVTSYQKALDLDPEND------SYKSNLKIAEQKL--------------REVSSPTGTG--------LTFDMASLINNPAFITMAASLMQNPQVQQLMSG--MMTN----AIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRSRSFSSSTEEHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96EQ0-1", "uniprot_id": "SGTB_HUMAN", "id": "Q96EQ0-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "aln": "--------------MSSIKHLVYAVIRFLREQSQMDTYTSDEQESLEVAIQCLETVFKISPEDT-------------HLAVSQPLTEMFTSSFCKNDVLPLSNSVP------------------EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPEND------SYKSNLKIAEQKL--------------REVSSPTGTG--------LSFDMASLINNPAFISMAASLMQNPQVQQLMSG--MMTN----AIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRSRSFSSSAEEHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R7L2-1", "uniprot_id": "F1R7L2_DANRE", "id": "F1R7L2-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein beta", "aln": "MTVERALRALSPDKMAVEKRLAYSMVQFLRDQTHCGSLNSDEQESLEVAIQCLETTFKISSSDC-------------HLAAPQPLREIFLNSLLKNDIVTLPKTFPS----------------PEDIERAEQLKNEGNNHMKEENYSSAVDCYTKAIELDQRNAVYYCNRAAAHSKLENYTEAMGDCERAIAIDPSYSKAYGRMGLALTSMSKYPEAISYFNKALVLDPEND------TYKSNLKIVEQKQ--------------KEASSPTATG--------LGFDMASLINNPAFISMAASVMQNQQVQQLMSG--MMSN----AVGGPAAGVGGLSDISSLIEAGQQFAQQIQQQNPELIEQLRNHIRSRSFSGSAEEHS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12118-1", "uniprot_id": "SGT2_YEAST", "id": "Q12118-1", "name": "Small glutamine-rich tetratricopeptide repeat-containing protein 2", "aln": "-------------MSASKEEIAALIVNYFSSIVEKKEISEDGADSLNVAMDCISEAFGFEREAVSGILGKSE-FKGQHLADILNSASRVPESNKKDDAENVEINIPE--------------DDAETKAKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNATEAMKRDYESAKKKVEQSLNLEKTVPEQSRDADVDASQGASAGGLPDLGSLLGGGLGGLMNNPQLMQAAQKMMSNPGAMQNIQK--MMQDPSIRQMAEGFASGGGTPNLSDLMNN-----PALRNMAGNLFGGAGAQSTDETPDNENKQ--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VJD4-1", "uniprot_id": "Q9VJD4_DROME", "id": "Q9VJD4-1", "name": "", "aln": "------------MPDAVQQSFVRSFIDYLKK--QGDVMSPDQTESIEVAIQCLQAAFDLGDDVEAAPAAAGEEQATTQSSSTASAPDDDAVASGSAGIGAAAAAVPNNIDMFELFQSLYTERNPESLALAESIKNEGNRLMKENKYNEALLQYNRAIAFDPKNPIFYCNRAAAHIRLGENERAVTDCKSALVYNNNYSKAYCRLGVAYSNMGNFEKAEQAYAKAIELEPDNE------VYKSNLEAARNAR-----------------NQPPQTG-------RLREDLINMLSQPMVRNLFNNAEIDVEQLLSMLQNPMIMN----TIRQQFGGGNAPTLPNDMVQMIYNMTSQLTGFPNSNANPGNEQQPGNQPPPST----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. .: :: . . . * :*::**::*:. .* : . : : . : . . .* * *:.:* :**. * ::.* *: *..** . *.::*.*****: * . *: *.: *: : .* :.* *:*.* .: :* : *.: :: :* *:* : ..: .. . :* * .: .::.:* . . : : *: : : .. .. . ..::: : . : .. . ", "identical_positions": 43, "similar_positions": 104, "identity": "11.23%" }, { "cls_id": "homologset.agr.MGI:2444626", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4J245-1", "uniprot_id": "TVAL1_HUMAN", "id": "A0A0B4J245-1", "name": "T cell receptor alpha variable 12-1", "aln": "-MISLRVLLVILWLQLSWVWSQRKEVEQDPGPFNVPEGATVAFNCTYSNSASQSFFWYRQDCRKEPKLLMSVYSSGN-EDGRFTAQLNRASQYISLLIRDSKLSDSATYLCVVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J271-1", "uniprot_id": "TVAL3_HUMAN", "id": "A0A0B4J271-1", "name": "T cell receptor alpha variable 12-3", "aln": "MMKSLRVLLVILWLQLSWVWSQQKEVEQDPGPLSVPEGAIVSLNCTYSNSAFQYFMWYRQYSRKGPELLMYTYSSGNKEDGRFTAQVDKSSKYISLFIRDSQPSDSATYLCAMS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A075B6T6-1", "uniprot_id": "TVAL2_HUMAN", "id": "A0A075B6T6-1", "name": "T cell receptor alpha variable 12-2", "aln": "-MKSLRVLLVILWLQLSWVWSQQKEVEQNSGPLSVPEGAIASLNCTYSDRGSQSFFWYRQYSGKSPELIMFIYSNGDKEDGRFTAQLNKASQYVSLLIRDSQPSDSATYLCAVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4J1N1-1", "uniprot_id": "A0A0B4J1N1_MOUSE", "id": "A0A0B4J1N1-1", "name": "", "aln": "-MHSLHVSLVFLWLQLGGVSSQEK-VQQSPESLIVPEGAMSSLNCTFSNSASQSIWWYQQHPGKGPEALISIFSNGNKKEGRLTVYLNRASLHVSLHIRDSQPSDSAVYLCAVS", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **:* **:*****. * **.* *:*.. .: ***** ::***:*: . * : **:* * *: :: :*.*: ::**:*. ::::* ::** ****: ****.***.:.", "identical_positions": 51, "similar_positions": 37, "identity": "44.74%" }, { "cls_id": "homologset.agr.MGI:2444628", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q498M5-1", "uniprot_id": "SH3R2_RAT", "id": "Q498M5-1", "name": "E3 ubiquitin-protein ligase SH3RF2", "aln": "MDDLTLLDLLECPVCFEKLDVTAKVLPCQHTFCKPCLQRIFKAH-KELRCPECRTLVFCSIEALPANLLLVRLLDGVRSGHNSWRGGSFRRPRILTLQDNRKAKSSPRSLQASPFRLGPTVRIHMDGVPRAKALCNYRGKNPGDLKFNKGDVILLQRQLDENWYQGEINGVSGFFPASSVEVIKQLPQPPPLCRALYNFDLRDKDKSENQDCLTFLKDDVITVISRVDENWAEGKLGDKVGIFPILFVEPNLSARHLLEKSKGHQLSRTKHLSLMSSPSRGKATNTSTLRKSPGSRRKGSGQFAMT--TALNTLNRMVHSPEGHQMVEISTPVLISSTSPSMLTQHGDRADFPASSAGQVSTSHPAPASPGHSTAMVSVP--SSQQHLSTNMFVALHTYSAQGPEELDLKKGEGIRVLGKNQDGWLRGVSLVTGRTGIFPSDYVIPVFSSTARKTSSFPDSRHPTVCTTWALSTS---SVSSQGSFSEGDPRQSGPFRSVFVPTAVN-PPRSTSGPGTSGQGSLRKVRSSMRKNG------------SLQRPVQSGIPTFMVGSLRCSP----AMVIRPQKFQFYQPQGMTPSP--TPIMVEIGSKSISTGEPALTCINRGGKTRTHSAGNSIIMEGKETPIKSEPPPKP------PASAPPSILVKPENSKNGIEKQVKTVRFQNYSPPPTKHSASGPTSGKHEQPATLKGSQPEAVSSEGEMTILFAHRSG------CHSGQQTDLRRKSAFSKTTPPVSTASVSQTLFPSK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZT2-1", "uniprot_id": "SH3R2_MOUSE", "id": "Q8BZT2-1", "name": "E3 ubiquitin-protein ligase SH3RF2", "aln": "MDDLTLLDLLECPVCFEKLDVTAKVLPCQHTFCKPCLQRIFKAH-KELRCPECRTLVFCSIEALPANLLLVRLLDGVRSGQSSWKGGSFRRPRILTLQDNRKAKSSPRSLQASPFRLVPSVRIHMDGVPRAKALCNYRGKNPGDLKFNKGDVILLRRQLDENWYQGEINGVSGIFPASSVEVIKQLPQPPPLCRALYNFDLRDKDKSENQDCLTFLKDDVITVISRVDENWAEGKLGDKVGIFPILFVEPNVSARHLLE-NKGHQLSRTRHLSLMSSPSRGKATNTSSLRKSPGSRRKGSGQFSMT--TALNTLNRTVHSPEGHQMVEISTPMLISSNSPSVLTQHGDKADFPTSSTGQVSSSQPAPASPGHSTAMVSVP--SSQQHLSNNMFVALHTYSAHRPEELDLQKGEGIRVLGKYQDGWLKGLSLLTGRTGIFPSDYVIPVFSSTARKTSSFPDSRSPTVCTTWALSTS---SVSSQGSFAEGDPRQSGPFKSVFVPTAVVNPSRSTPGPGSSGQGSLRKVRSSMRKNG------------SLQRPVQSGIPTFMVGSLRCSP----TMVIRPQRFQFYPPQGMTPSP--TPIMVEMGSKSIYTGEPALTCINRGSKTRIHSAGNSIIMEGKETPIKSEPPPKP------PASAPPSILVKPENSKNGTEKQVKTVRFQNYSPPPTKHSASSPTSGKHDHPATLKGSQHEAVSSGGEMTILFAHRSG------CHSGQQTDLRRKSAFGKTMPLLSTASATQTLFPSK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEC5-1", "uniprot_id": "SH3R2_HUMAN", "id": "Q8TEC5-1", "name": "E3 ubiquitin-protein ligase SH3RF2", "aln": "MDDLTLLDLLECPVCFEKLDVTAKVLPCQHTFCKPCLQRVFKAH-KELRCPECRTPVFSNIEALPANLLLVRLLDGVRSGQSSGRGGSFRRPGTMTLQDGRKSRTNPRRLQASPFRLVPNVRIHMDGVPRAKALCNYRGQNPGDLRFNKGDIILLRRQLDENWYQGEINGISGNFPASSVEVIKQLPQPPPLCRALYNFDLRGKDKSENQDCLTFLKDDIITVISRVDENWAEGKLGDKVGIFPILFVEPNLTARHLLEKNKGRQSSRTKNLSLVSSSSRG---NTSTLRRGPGSRRKVPGQFSIT--TALNTLNRMVHSPSGRHMVEISTPVLISSSNPSVITQPMEKADVPSSCVGQVSTYHPAPVSPGHSTAVVSLP--GSQQHLSANMFVALHSYSAHGPDELDLQKGEGVRVLGKCQDGWLRGVSLVTGRVGIFPNNYVIPIF----RKTSSFPDSRSPGLYTTWTLSTS---SVSSQGSISEGDPRQSRPFKSVFVPTAIVNPVRSTAGPGTLGQGSLRKGRSSMRKNG------------SLQRPLQSGIPTLVVGSLRRSP----TMVLRPQQFQFYQPQGIPSSP--SAVVVEMGSKPALTGEPALTCISRGSEAWIHSAASSLIMEDKEIPIKSEPLPKP------PASAPPSILVKPENSRNGIEKQVKTVRFQNYSPPPTKHYTSHPTSGKPEQPATLKASQPEAASLGPEMTVLFAHRSG------CHSGQQTDLRRKSALGKATTLVSTASGTQTVFPSK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QGN1-1", "uniprot_id": "A0A8M9QGN1_DANRE", "id": "A0A8M9QGN1-1", "name": "", "aln": "MEDLAVMELLECPLCMEPLDVSAKVLPCQHTFCKSCLQQQETSHPDQLCCPECRAAVPGSVEELPTNPLLHRLLESLH------EWGPVSTPRDRSVR---YMSSPAQEDHCSSYTQDLPKQEQNTQRVQAQALYDFQGNAPGELTMKSGDIIYLRWRVDDNWYYGEGKDSRGLVPVNVLQVLSEQPQPLALCRALYDFNANNLDPEGSKECLTFFKGDSITLLKQVNENWVEGKLGDKVGIFPLQLTEPNPAAYELLEKHKRRDSVEAQPRSSVRVNADACIHRRLTGPSQKSSRPSNVNLLNSLNCPPLSLSQQPPHISSSAQPSYSKTPQLATFNRPRLRSSRRNLPKRHRTMNGESPPAITMALINPQASPMPSESKMSATQQLSISVCAALYSYTPYRSEELELRKGEMVGVYGKFSEGWLRGLSLKTGKVGILPTNYVTPVL----RTSARFLEQSKPAIPNSSAVSTKRHASHKPQAVVLALDRVNTDSPSATMPVTSSAGPGRAAQLGGKQGWSSVRRSFHATHRGLPHHGSYNSNSILSLQPPPQDLGQIYTFGRSPVLPKKRNGLFSNPMKAQHWAYETTSPSAGAYQPIINPGQKETTTTRQSILVKPDAYKNNAEKPVKSVRFLAHDTPQTAPKTPSTSTAGLSSSSQPGFSTLDHWNPSAILGRDGHTLVLKDTKTPPARKSTGQDHAAMDSLALNMKPVLINNQSGSSRCRVIKGYNAKTDAELTLTEGEMVLVQRPRADGRVLVTQEISGKTGLFQSSVLELLDKIL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**::::*****:*:* ***:************.***: .:* .:* *****: * .:* **:* ** ***:.:: . *.. * ::: : .: :.*.: : : :*:** :::*: **:* ::.**:* *: ::*:*** ** :. * .*.. ::*:.: *** .******:*: .. * . .::****:*.* **::.:*:***.************: :.*** :* .*** * :: .:: * : : . . : .** . . : ..*. :: * ... : .** * : . * : :. : .. : *: .. . . :::.: * . .: *:** .: .**::*:. .:**:*:*** : * ** .:***:*:** **:.**:*.:** *:: *.:: * :. * : .: ::**. * ..*. . * :: . :.: *: * *:: *. * .*:*: : ::. *** * *. .* * :. .* : *.: : ..*. ::: *.* * . :: . : ... .*: : :: * .: *.. .:* * :. *. :: :*: ::: ..**::: :. :. . . .:* : * . :: .:.: .*: . ::* * .:. . :. : . .* ", "identical_positions": 194, "similar_positions": 266, "identity": "24.81%" }, { "cls_id": "homologset.agr.MGI:2444629", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNX0-1", "uniprot_id": "D3ZNX0_RAT", "id": "D3ZNX0-1", "name": "BTB/POZ domain-containing protein KCTD3", "aln": "MAGGHCGSFAAAAASSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFLRTKELDLRGVSINVLRHEAEFYGITPLVRRLLLCEELERSSCGSVLFHGYLPPPGIPSR----------KGTNTARSSVDARNG------LSSMEGEAR--------------GSGTQP---VLAGNG--------------------EDTIRLGVP-------VDPRKVLIVAGHHNWIVAAYAHFAVCYRIKESSGWQQVFTSPYLDWTIERVALNAKVVGGPHGDK-DKMVAVASESSIILWSVQDGGSGSEIGVFSLGVPVDALFFIGNQLVATSHTGKVGVWNAVTQHWQVQDVVPITSYDTAGSFLLLGCNNGSIYYIDMQKFPLRMKDNDLLVTELYHDPSNDAITALSVYLTPKTS-VSGNWIEIAYGTSSGAVRVIVQHPETVGSGPQLFQTFTVHRSPVTKIMLSEKHLVSVCADNNHVRTWTVTRFRGMISTQPGSTPLASFKILSLEETESHGSYSSGNDIGPFGERDDQQVFIQKVVPITNKLFVRLSSTGKRICEIQAVDCTTISSFTVRECEGSSRMGSRPRRYLFTGHTNGSIQMWDLTTAMDMVNKSE--DKDAGGPTEEELLKLLDQCDLSTSRCATPNISPATSVLQHSRLRESSSSLQLQHHETIHEAATYGATRPYRESPLLARARRTESFHSYRDLQTLNLNRTVERAVPENGHTGPAQAEAKGAAAGECAVCERKSPGTEGRCVREPDVGLDVHRPAEGLSEPKKRSTEDENEPKVEFRKKG-FEAGGFLGRKKVPYLASSPSTSDGGTDSPGTASPSPTKTTPSPRHRKSDSSGQEYSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFX3-1", "uniprot_id": "KCTD3_MOUSE", "id": "Q8BFX3-1", "name": "BTB/POZ domain-containing protein KCTD3", "aln": "MAGGHCGSFAASAASSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFLRTKELDLRGVSINVLRHEAEFYGITPLVRRLLLCEELERSSCGSVLFHGYLPPPGIPSR----------KVTNTARSSVDARNG------LNSMEGEAR--------------GNGTQP---VLAGNG--------------------EDTIRLGVP-------VDPRKVLIVAGHHNWIVAAYAHFAVCYRIKESSGWQQVFTSPYLDWTIERVALNAKVVGGPHGDK-DKMVAVASESSIILWSVQDGGSGSEIGVFSLGVPVDALFFIGNQLVATSHTGKVGVWNAVTQHWQVQDVVPITSYDTAGSFLLLGCNNGSIYYIDMQKFPLRMKDNDLLVTELYHDPSNDAVTALSVYLTPKTS-VSGNWIEIAYGTSSGAVRVIVQHPETVGSGPQLFQTFTVHRSPVTKIMLSEKHLVSVCADNNHVRTWTVTRFRGMISTQPGSTPLASFKILSLEETESHGSYSSGNDIGPFGERDDQQVFIQKVVPITNKLFVRLSSTGKRICEIQAVDCTTISSFTVRECEGSSRMGSRPRRYLFTGHTNGSIQMWDLTTAMDMVNKTE--DKDAGGPTEEELLKLLDQCDLSTSRCATPNISPATSVLQHSRLRESSSSLQLQHHETIHEAATYGATRPYRESPLLARARRTESFHSYRDFQTLNLNRSIERPVPENGHMGPAQTEVKG-AAGECAMSERRSPGTEVRCGRESDGGLEVHRTAEGLSEPKKRSAEDENEHKVEFRKKG-FEAGGFLGRKKVPYLASSPSTSDGGTDSPGTASPSPTKTTPSPRHKKSDSSGQEYSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y597-1", "uniprot_id": "KCTD3_HUMAN", "id": "Q9Y597-1", "name": "BTB/POZ domain-containing protein KCTD3", "aln": "MAGGHCGSFPAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFLRTKELDLRGVSINVLRHEAEFYGITPLVRRLLLCEELERSSCGSVLFHGYLPPPGIPSR----------KINNTVR-SADSRNG------LNSTEGEAR--------------GNGTQP---VLSGTG--------------------EETVRLGFP-------VDPRKVLIVAGHHNWIVAAYAHFAVCYRIKESSGWQQVFTSPYLDWTIERVALNAKVVGGPHGDK-DKMVAVASESSIILWSVQDGGSGSEIGVFSLGVPVDALFFIGNQLVATSHTGKVGVWNAVTQHWQVQDVVPITSYDTAGSFLLLGCNNGSIYYIDMQKFPLRMKDNDLLVTELYHDPSNDAITALSVYLTPKTS-VSGNWIEIAYGTSSGAVRVIVQHPETVGSGPQLFQTFTVHRSPVTKIMLSEKHLVSVCADNNHVRTWTVTRFRGMISTQPGSTPLASFKILSLEETESHGSYSSGNDIGPFGERDDQQVFIQKVVPITNKLFVRLSSTGKRICEIQAVDCTTISSFTVRECEGSSRMGSRPRRYLFTGHTNGSIQMWDLTTAMDMVNKSE--DKDVGGPTEEELLKLLDQCDLSTSRCATPNISPATSVVQHSHLRESNSSLQLQHHDTTHEAATYGSMRPYRESPLLARARRTESFHSYRDFQTINLNRNVERAVPENGNLGPIQAEVKG-ATGECNISERKSPGVEIKSLRELDSGLEVHKIAEGFSESKKRSSEDENENKIEFRKKGGFEGGGFLGRKKVPYLASSPSTSDGGTDSPGTASPSPTKTTPSPRHKKSDSSGQEYSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A6H2EG81-1", "uniprot_id": "A0A6H2EG81_DROME", "id": "A0A6H2EG81-1", "name": "BTB domain-containing protein", "aln": "MS-------HFTHASSSDLVNLNVGGQRFSTSRQTLTWIPDTFFTALLSGRISSLRDEHNAIFIDRDPTLFSIILNYLRTKDIDIKNCEIRALRHEAEYYGITPLTKRLALCEDLNHSSCGDLLFYGFLAAPPMPSNEAVAATSVDESLPSTSASAIGSRPGSMVRVPEPSRSSHSRNSSWDLRLGRTGSTGNGANPPAPMLHSRNPSIDFMRHSRNSSADLNKVFRNEVGLVFSPTQNSNWVDPLRVQIIKAHQNWIAVAYAHFVTCYRVKDSNGWQQVFTSPHIDATIERIAINSKVNTSAAEPLPSKMVAISYGSQIRLWSIQEGGQKTDVGTFNLNVRVEYLFFIGSQLVALSSSGKIGVWHAMTQHWQIQDLVPVLSFDSAGSFLLLGCNNGSIYYIDMQKFPLRIKDNDLLVTELYKDVTLDPITAISVYLTPKTSSISGNWIEIAYGTKSGAVRIIVQHPETAGHGPHLFETFFVHQSPVTKVMLSEKYLVSVCSEYHHVRTWRLTRFRGMLSTQPGSTPEASFKIVSLEATDTSYSYAAGNDFGPYGDYDD-MIFVQKVVPETDQLYVRLASNGDRVCVIRSVDSSTISAFCVLECEVSS-------RFILTGHCNGAIQMWDLTTALALLSKDEPQQKINGGPDTNELLRLLDQCEISNSSCTTPCMSPCLSAMGNGSGMASS----------IARMKASNIALLNRE-PAMAMA---------------------VQAVQPPAQVQPALPEAVAPAAAIPMADDNNEXDVEAAAX------LALVGRVSSFTFHRYSLIFDYQFIFLQFVVCA-------LIYVWVTRLTRGPATGP----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: : *.*.::*:***** ********* ****:**::*******:**** .********: *: ***:****::*::. .*..******:******.:** ***:*::****.:**:*:*..* :**. . .* : .:* * * ...:* *.*::* :* . . .: : * .. *** :* *: .*:***..*****..***:*:*.*********::* ****:*:*:** .. .****:: *.* ***:*:**. :::*.*.*.* *: *****.**** * :**:***:*:*****:**:**: *:*:*************************:***********:* : *.:**:********* :***********.*****:*******.* **:**:** **:*****:*****:*****:: :***** :******:******** *****:*** *:: **::***:**:*: ** :*:***** *::*:***:*.*.*:* *::**.:***:* * *** ** *:::*** **:*********: ::.* * :* *** :***:*****::*.* *:** :**. *.: :. *. . : . ** * :* * :.* .: * .*. . *:. :... ..* . * : ...:: : * : ::* . * *. *: .*:*. ", "identical_positions": 391, "similar_positions": 199, "identity": "44.38%" }, { "cls_id": "homologset.agr.MGI:2444630", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZMW1-1", "uniprot_id": "A0A8I5ZMW1_RAT", "id": "A0A8I5ZMW1-1", "name": "", "aln": "MHLHQVLTGAVNPGDNCYSVGSVGEVPFTAYGSGCDIVILASDFECVQIIPGAKHGNIQVSCVECSNQHGRVAASYGNAVCIFEPLGIN--SHKRNSQLKCQWLKTGQFFLSSVTFNLAWDPQDNRLLTATDSIQLWAPPGSDILEEEE---------------EVDNKVPPVLNDWKCIWQCKTSVSIHLMEWSPDGEYFATAGKDDCLLKVWY-------PMTG-WKSSIIPQDPHEVKRRRAST-----QFSFVYLAHPRAVTGFSWRKTSKYMPRG-SVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSVASNLSSAGKH--KDRIQHALETIHHLKNLRKGQ-------------------------RRSSVLVTHAELMPDKTATHEVHRHISHHAN-----ALCHFHIAASINPATDIPNVLVGTAFNIDDINGGFVVHWLNNKEFHFTSSTEIFMHQLR-KLSEKQLDHE---SDDADREDDER--SQEERERGLRMKLDHELSLDRESEAGTGSSEHEDGEREG------------------SPRTHPRPSVSLPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDANSLSKNIMMY-------ACVNATKDSYSTTSQPELMSVDSSHGSQPHY---------------------------------------------TSHSTDWN------------ILAPTVMMVSKHIDGSLNQWAVTFADKS-AFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPEADCQWDTDSKLNRLIDPVKHTKGSSKQP-LRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPE----------ASKLIG--------------EVFNIVSQQSTARPGCIIELDAITDQCG--SNTQLLHVFQEDFIIG--YKPHKEDMEKKEKETEIFFQPSQG-----YRPPPFSEKFFLVVIEKDGNNNSILHMWHLHLQSVQ--ACLAKAAEGISSDSLLSVPGQKNMESSSE---TSSSVSSMPHSSSIANLQTASKLILSSRLVYSQPLDLPEAVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCCMETNSPCSSSGENETYHWRRWPLMNDEEKDNSSTVSIVGRPVAVSCSYTGRLAVAYKQ------PIHHNGFISKEFSMHVCIFECESTGGSEWVLEQTIHLD----DLVKVGSVLDSRVSVDSNLFVYSK---------------------------------------------SDAFLSKDRYLIPN-------IKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVNDQ----TNSKDGVAVITLPLGGSIKQG---VKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWK-------------------HSVKFGDVEADSP-VEQTIIQDHSAFKSSMLTRKSIAEGAAIPDDVFCSP------------------------------TVVQDGGLFEAAHALSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAG-EVAIVRDPDAGEGTKRHLSR--TISVSGSTAK--------DTVTIGKDGTRDYTEIDSIPPLPLHALLAADQDTSYRISEDSAKKPQSYEDHIESQPEDQYSELFQVQEITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTS--TELDE--NRDKNYSG-----------------RDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNVNTLRRCIEKVAKAAFQR--NNDALDAALFYLSMKKKAVVWGLFRSQH----DEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLFESEFETSSTYISILNQKILGCQKDGTGFNCKRLHPDPFLRSLAYWVMKDYTRALDTLLEQTP-------KEDDEQQVIIKSCNPVVFSFYNYLRTHPLLIRRNLASPE------------------GTLATLGLKTEKNIADKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKISSLNAKKDQLDFVSERMENGPSESKPVSSSDGGSGADWLAVTSSQFDWSQPIVTVDEEPLRLDWGEDHDGALEE--DDGGGLVMKAADAKKAGQ--DQRASDPSALLTPQEEDCAEGDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSS---KAYSKVESELLDHEEMVDKPDIGSYERHQIERRRLQAKREHAERRKLWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMRTPP-QPSVEDVKVHTLHSLAASLSASIYQALCDSHSYSS---QTDGNQFTGMAYQGLLLS------------DRRRLRTESIEEHATPNSAPAQWPGVSSLINLLSSAQDEDQPRLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVK-LVVKPRRQS------------------------ESIAAPPVASEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESVHSDDEEDD-------AFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNIKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDHFEGPPPNYVNTYPTDLSVGAGPAILRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFIRYIFTK---------KRKQSEVEADLGYPGGK------AKVIHKESDMIMAFSINKANCNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDIDYRGSTTTLYQPGAAS--HSSSQVHPPPSLPWLGSGQTSTGATVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAG-NARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGQSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLMHTFQAHDSAIKALALDSCEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIEISQDNRLFSCGADGTLKTRVLPSAFNIPNRILDIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BPN8-1", "uniprot_id": "DMXL2_MOUSE", "id": "Q8BPN8-1", "name": "DmX-like protein 2", "aln": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILASDFECVQIIPGAKHGNIQVSCVECSNQHGRVAASYGNAVCIFEPLGVN--SHKRNSQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGGDILEEEE---------------DVDNRAPPVLNDWKCIWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWY-------PMTG-WKSSIIPQDPHEVKRRRAST-----QFSFVYLAHPRAVTGFSWRKTSKYMPRG-SVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSVASNLSSAGKH--KDRIQHALETIHHLKNLRKGQ-------------------------RRSSVLVTHAELMPDKTATHEVHRHISHHAN-----ALCHFHIAASINPTTDIPNVLVGTAFNIDDINGGFVVHWLNNKEFHFTSSTEIFMHQLR-KLSEKQLDHE---SDDADREDEER--SQDERERGLRMKLDHELSLDRESEAGTGSSEHEDGEREG------------------SPRTHPRPSISMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDANSLSKNIMMY-------ACVNATKDSYNP-SQQEMMSVDSPHGSQLHS---------------------------------------------PSHSTDMN------------ILAPTVMMVSKHIDGSLNQWAVTFADKS-AFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDCQWDSDSKVNRLIDPVKHTKASSKQP-LRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPE----------ASKLIG--------------EVFNIVSQQSTARPGCIIELDAITDQCG--SNTQLLHVFQEDFIIG--YKPHKEDMEKKEKESEIFFQPSQG-----YRPPPFSEKFFLVVIEKDGNNNSILHMWHLHLKSVQ--ACLAKAAEGISSDSLLSVPGQKNLDSSPE---TSSSMSSVPHSSSIANLQTASKLILSSRLVYSQPLDLPEAVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCCMETNSLGNTSDESETYHWRRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQ------PIHHNGFISKEFSMHVCIFECESTGGSEWVLEQTIHLD----DLVKVGSVLDSRVSVDSNLFVYSK---------------------------------------------SDAFLSKDRYLIPN-------IKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVSDQ----TNSKDGVAVITLPLGGSIKQG---VKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWK-------------------HSVKFGNVDADSP-VEET-IQDHSALKSSMLARKSIVEGAAIPDDVFCSP------------------------------TVVQDGGLFEAAHALSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAG-EVAIVRDPDAGEGTKRHLSR--TISVSGSTAK--------DTVTIGKDGTRDYTEIDSIPPLPLHALLAADQDTSYRISEDSTKKPQSYEDHIESQSEDQYSELFQVQEITTDDIDLEPEKRENKSKVINLSQYGPACFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTS--TELDE--NRDKNYSG-----------------RDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNVNTLRRCIEKVAKAAFQR--NNEALDAALFYLSMKKKAVVWGLFRSQH----DEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLFESEFETSSTYISILNQKILGCQKDGTGFDCKRLHPDPFLRSLAYWVVKDYTRALDTLLEQTP-------KEDDEQQVIIKSCNPVVFSFYNYLRTHPLLIRRNLASPE------------------GTLATLGLKTEKNIADKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKISSLTAKKDQLDSVSGRMENGPSESKPVSRSDGGSGADWSAVTSSQFDWSQPMVTVDEEPLRLDWGDDHDGALEE--DDGGGLVMKTTDAKKAGQ--EQSASDPRALLTPQDEECADGDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSS---KAHSTVETERLDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKLWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPP-HPSVEDVKVHTLHSLAASLSASIYQALCDSHSYS----QSEGNQFTGMAYQGLLLS------------DRRRLRTESIEEHATPNSAPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVK-LVVKPRRQS------------------------ESIAAPPVASEDMDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESVHSDDEEDD-------AFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNIKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDHFEGPPPNYVNTYPTDLSVGAGPAILRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFIRYIFTK---------KRKQSEVEADLGYPGGK------AKVIHKESDMIMAFSINKANCNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDIDYRGSTTTLYQPGAAS--HSSSQPHPPPSLPWLGSGQTSTGATVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAG-NARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIAISQDNRLFSCGADGTLKTRVLPSAFNIPNRILDIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDJ6-1", "uniprot_id": "DMXL2_HUMAN", "id": "Q8TDJ6-1", "name": "DmX-like protein 2", "aln": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSNQQGRIAASYGNAVCIFEPLGIN--SHKRNCQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGDDILEEEE---------------EIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWY-------PMTG-WKSSIIPQDHHEVKRRQSST-----QFSFVYLAHPRAVTGFSWRKTSKYMPRG-SVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSIASSLSHAGRH--KDRIQHALETIHHLKNLRKGQ-------------------------RRSSVLVTHAELMPDQTAMHEVQRHISHHAN-----ALCHFHIAASINPATDIPNVLVGTAFNVDDGNGGFVVHWLNNKEFHFTSSTEVFMHQLR-KLSDKQVDHE---NDDADREDEEH--SQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREG------------------SPRTYSRLSVPMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMY-------ACINATKDSHHTLLHQEGMSVGSPHGSQPHS---------------------------------------------RSHSTHMN------------ILAPTVMMISKHIDGSLNQWAVTFADKS-AFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQP-LRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPE----------SSKLIG--------------EVFNIVSQQSTARPGCIIELDAITNQCG--SNTQLLHVFQEDFIIG--YKPHKEDMEKKE--TEIFFQPSQG-----YRPPPFSEKFFLVVIEKDSNNNSILHMWHLHLKSVQ--ACLAKASEGASSESLLSVPGQKNVDSSPE---TSPSVSPMPHSSSIANLQTASKLILSSRLVYSQPLDLPESVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCCMEANPECNKSDEKEIYHWKRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQ------PIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLD----DLVKVGSVLDSRVSVDSNLFVYSK---------------------------------------------SDALLSKDRYLIPN-------IKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTEQ----TNSKDGVAVITLPLGGSIKQG---VKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWK-------------------HAVKFGDTEADSSNAEEAAMQDHSTFKSNMLARKSVVEGTAISDDVFCSP------------------------------TVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAG-EVAIVRDPDAGEGTKRHLSR--TISVSGSTAK--------ETVTVGKDGTRDYTEIDSIPPLPLYALLAADQDTSYRISEESTKIPQSYEDQTVSQPEDQYSELFQIQDIPTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTS--TELDE--SRDKSCSG-----------------RDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQR--NNDALDAALFYLSMKKKAVVWGLFRSQH----DEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESEFETSSTYISILNQKILGCQKDGSGFSCKRLHPDPFLRSLAYWVMKDYTRALDTLLEQTP-------KEDDEHQVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPE------------------GTLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKTSALSAKKDQPDFISHRMDDVPSHSKALSDGNGSSGIEWSNVTSSQYDWSQPIVKVDEEPLNLDWGEDHDSALDEEEDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSS---KTYSKVESDLLDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPP-HPSIEDVKVHTLHSLAASLSASIYQALCDSHSYS----QTEGNQFTGMAYQGLLLS------------DRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNILLCEAVVAVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFGGGVK-LVVKPRRQS------------------------ENISAPPVLSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESIHSD-EEDD-------AFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAGPAILRNKAMLEPENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTK---------KRKQSEVEADLGYPGGK------AKVIHKESDMIMAFSVNKANCNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDVDYRGSTTTLYQPSATS--YSASQVHPPSSLPWLGTGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAG-NARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGADGTLKTRVLPNAFNIPNRILDIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W425-1", "uniprot_id": "Q9W425_DROME", "id": "Q9W425-1", "name": "", "aln": "MNCHQILSGACNAGDRCFAIGSVEGIPFTAYAAGCNVVILASTFERVQIIPGANHGYVKISALDCSTDTGKIAAAYENKICIFEPTPVIESSKHNTHFLDYRWVQTGSFTSHSNVVTLSWNLEGTRLLTGGTNIQLWKSKSPTHQQEEEHTGVKFEIGESKEPKQTSNAQSEDVSTWENIWSCQTAIPIYHMAFSPDGTLFATCGRNDRLVKIWYENKQVLFPAKGSSNAGPTPSCRHGVDDGTTSSSGGELNFTYVYIAHPRAVSNIVWRKTSKYMPKG-SVANMLVTSCLDNICRIWIETVLPDDGMVNMTQFDPMASQNPKFRTHRHKHRFMQRLKHMKTCFHIRRHMKAGASAVPGAASAGAASGGGTAGAMGGMGSSPASYTNYLGPIPSLPSSCSVHDFHSYGFQGSGVTPGMHFHLAASINAETDIPLVPSMQTSDPANQN-VFILHWLNNKEMHFTLQAEAILQELTKKVIDEENGHGNASSGGVDLPDDAHGSHSQAHAHKKYLRSSKSVSVDDSGEEFSRYSQHTAGTGMGGGGGGAGLHLNSMSNTTSQNSLNNEPAHPITQLVDSLDNKIECLLRDWHQSPDLLFAIHPVDGSYLIWVIEWLDDYYPGSFRQAQVSFSTRIPSAFPLGDAMSMSTTVSLFNTGTHPLAFRDIANNVRSKDEFHKGHADDSSLKSDQHSGQTFERHDEEQEDAADDDGDGDREGDADQDEGGGDRSAAASGGGAAEHSSSSQDSAATGASALPLNVSPSVSMVTKHSNGTLNLWQLTFAFKT-KFTQVLSIGHVSRASGHRFRVNDITCHPVLPLLVSTSHHN---LPDSEAKSPMSLFEQPLSGGLPSGGGTGAGPSVGSNGDKDVFTPTGFCSELILWRVDSVGPLCHSGGVSELARINSPEISAFSNVAWIPTLLPSTTLGSYSNSPSACFVASDGENLRVYQAVIDARTLLAEISCSENLNTLHKSHSLSSMISNASSTMRAQRSALHDKLKVVSQQSTARPGCILQLDAISDAKHDWQNTQFLHVFQAQLITGGQRTPQADPHDLEEPRLNALLESDMDAIVDLQRNADFEEPFYIVNIEKTLRG-STIHMWRIVISSKQQSSFLSETAMYVPDSNLTQEPDEDGAGGNPNPRRMSQGAETLTGAEHFGPQVEAPHISITTKKVCTQELPLPEGVDVIHASPAAGHLSSSSIYPACFAPYIIVTACSDSISRFWKCEPIGD-EDDPNPEGDAYHWSEWKMFS---RIQHSAIEIPGQPLNISAAYSGRIACAYKYGKSFTRPNKGPDPDSRYVNLCVAIYECESSGGSEWVLEDTIHLKNVHLPRINIGHGIDLSYLHDSRLLAKKQRLNQVLHTFAHDPESRSPRSGETTPELAVNRQPSAAASGLLTVPSFSTLQSLRKSIAENGNTCPLTQKHLVQLDWVSKEDGSHILTVAVGSKILLYTPVSSDIAQANIKAMKESRSVNRPILRKASSLAQPNFVDEIRWMKLRQIDLQT-ADGLPPLPMQISWVRDGILVVAMDSEMHVYSQWKPHYSSHFAAAAAAAGEDVPDTRNLRDEDLRSLANESTQLRLKNVASMPLISKVSTANLQLLSHDKKRRLGNTSMANMNGAGGAGGTGTYGGGADDGGNDDYMTDFGLFQASRIACPVLPQYHPKQLMELLNCGKIRWVKAILAHLVRCMSGNSSSTVNQDDDGYARQRSWSRSRTLSISYTADQNIQAEHRGSTTQIPEELMLDYAEINSIPPLPLWVLLNADRETPGQSNNYAEGDKDYDELFDMHNSEDNLDELLSEGD----------EKKRQERRLSLPEKHSISHFGPRQGQLLSRLLTHTHLPGLSSLDQMHLLALADTVATCN--TDFSDKFAADQGKSGGMAGGAGSGAVKDGSTSTDSLDDCGLRFLLAMKHFTYLLRCLPLQQRAQFQRQGVGTSNIVWAFHSESEEELLNLIPSYTKGDLRWATLRDLGVGYWLKNINTLRRCVEKLAKCAYQQ--KQEPLDAAIYYLAMKKKSLVWGLFRSRR----DEKMTAFFGNNFAEDRWRKAALKNAFVLLGKQRFEHAVAFFLLANSLNDAIEVCMNKLEDFQLALIIARLYEGDGE-GCYYHHLLHEHILGTDAATGRCDLSRAHPDPFLRSMTYWTIKKYQESLNTLLLNNVGSLHSSYREEDLLRPEQQATNPNVFNFYIYLRTHPLLIRQNIALSAQEKRIAHVVLSGFNYAGDAAPSAVACDKQLQLEDSITPIERQLYFTTAHGHFKSGCPALALEVLNKLPQKISDDSGGSVAGSQAQERAQQNKEELINTGIMDQWGATPAAASN-TADAFDWGAPVSSEPEAKFEIKWDDEDEEEDPDLEPDEPELATPQPQAPILGR-----------------GKSNGNDTKMDIMAQQLKFVACLKILMEELSTLATGFEVDGGQLRYQLYMWLEREVEALKQLCNYCSQAEQSSHESGDADAEARDKEMNASIYPSTERPTLHEILMQDKQDFEAKVMRAAKRKRWLKANETLLRTLLSYCSLHGASGGGLASVRMELVLLLQELQQEKTQQQLLSPLPFPTTLPLLSACVAGNKTVIADPIKYLQSQTVDMLQSIIKVLPFPGIEPSALSEIFVLRDLAVALSSCIYQSLCDSESFVVNNSAFNGYPSPGMENIAKINSSFECSYLVGSRNAYGRRRKYSTDEPAGVCTTPSKWPGVTNLRALLAREKDEDVPKLNVLLLESFVSTYMALFIYSLSTCDSRLLYRLSGQSFNNETWSTLFGGGMKKLLIKPAAAPPPTQMVTGGAGAGGASGGTGSTSEEPTDENSVWNTVTSITKQRMKLNMKILGSFSQNSTSSNMKEDKPTYREQFMPPETSMLSYFLTKPPTTECDDYDTDDSHESDNEEEEEDDDDVNVSRSQLKAKDNTEHTNPTSYSWSILRLALIKISTHKIQELVKVAGIELQDLPVISPLSHEVLRTLNRWQDFALSDLIARGPPSRNYIPGCYAESGING-LAIHKYRSLLNKDNTPFVS-GSSAGPIRRLWNYLVRQEPAQEVFIKSIFVKNMEPSTRGSHHTNNDNETDEGQSHSTNENTDHIRIIHKDHESILSFCLKNNSSSMIAFANPREIQEFDISLLLESPNWYEDECDYDMMN-LSKDADTNSSSFLIIQTQEQNQFGSNSNAYSESNASTQSASQSGRGTSMVLRHKVDNVKRMSAHPLMPLYLTGGQDGSVQIWEWGHQQPVCSPRTSGTFAKVTRCRFSEQGNKFGIGDGDGKLSLWQAGIASQNNRSFISYQCHNKALSDFVFLGSCSLLASAGQSSENKNINIWDTLLPHKKSCVSAFTCHDQGSSCLVFAPQHQVLISCGKRGDVCVFDVRQRTLRHRYQAHDSTIKCIALDPHEEFFVTGSIEGDIKIWDMNQFMLINTFPHEHAKNGFFKHTGQGVSQVYVDAFGRLFSCGSDGCMKVRLLVEKDNIVHSVY---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P47104-1", "uniprot_id": "RAV1_YEAST", "id": "P47104-1", "name": "Regulator of V-ATPase in vacuolar membrane protein 1", "aln": "-MSLNFLPGRPNATPQTACQATWQNHTIFAYCSGNNLIILTNKFTRLQTIYTQSD----CTAVDINSQNGFIALSFHNRVLIYKPIHQI--------MQNPKWTQCCQLFHDDTPVNCLRWSSDNELAIGSDFLSFWKIKDN-----------------------------FGVYQPILQWNQKQPKPVYNVIISQDSQLIVSIGKYDCNAKLWK----------------------------RVSIVGEQAIFNLTMLPHPKPITAMRWKKEPDQVSKNNTASHALYTLCEDKVLRIWSCFEMEKN----------------------------------------------------------------------------------------------------------------------------HTVQIWGEVPLSPTQKFCVIIDNWIIRQTLSVKDSEIFDISDSD------------------------------------------------------------------------------------------------------------------------IVILGSMTGEMEVLALNNLSQDPPKPMTKKTISHKKVKKATMLNDTRYLYLPEIQPYD------------------------------------------------------------------------------------------------------NVKGKLSFLVHDLQGVIRHLLIDILQLINNKTEDLSAALEHKFTGHNKSVQKLVRSSDGEALLTTSRFS-------------------------------------------------------------------------------------ENGVWYPQKLN------------------HGVSLRLQNTIQTESPIKFAVVHELG----------------------------------------KQVICLLENGALQAWECP--------------------TNRKEDSEQKQSYLRVETRLKEE-----------KKIHPIVMLNTPEPKHSHERHFTALIFSDG----SIKAFEVSLTRGIFEVKSDS--------------------------------LDIDGDDIYKISIIDPVHQTFVSNRPLISLITKKGLT----RTYKAIVNYNDRHVQWIKACEINTGIMNCT--------------------------------CIRGSSTGKLCIVNST-----------GKVMSLWDLNRGVLEYEETFHN-----------------------------------------------------------------------------------------------------------PIEDIDWTSTEYGQSIVSIGFTGYALLYTQLRYDYTNN-----------------------------TPSYLPIEKIDITAHTAHN---IGDSVWMKNGTFVVASGNQFYIK--------------------------------------------DKSLDLTDPFTYQSIGSRKILSND------------------------------------------ILHLSSVLNGPLPVYHPQFLIQAIYANKLQLVKELLLRLFLALRKLDFESQDVSNLDSN---------------------------------------------LGMDPLKYFIAKDRDYPVESFPDP-----------------------------------------------------YPCFNKTVSLALTEQLTKTTLPYLTRHQQITLITVIEAVDEVTKNENI--------------------------------VDYNGVRFLLGVKLFLSHKN----------IQKSILMRDVSWALHSDNKE---ILLSSIDRHITSWNRAREYRIAYWIKEQ-DLVKKFEDIAKYEFSKDDKRDPSRCAIFYLALKKKQILLSLWKMAIGHPEQQKMVRFISNDFTVPRWRTAALKNAFVLLSKHRYMDAAVFFLLTDSLKDCVNVLCKQVHDMDLAIGVCRVYEGDNG-----------PVLGELLTAQMLPETIKENDRWKASFIYWKLRKQEVAIKALLTAPID-----------LENNSSIVDKEVCVNRSFLVEDPALLYLYNHLRN-----------------------RNLKYFIGSLNVEAKIECTLILRVTDILCRMGCNYLAVSLVKN----------------------------------------------------------------------------------------------------------------------------------------------------------------------WKFIERNSIPVQKLLKSPTKDR-------------------------------------------------------------------AYSAIGAMASEPISTARMR-----------------------------------------------------------------------------------------------------------------------------------------------------------------PSLFDKFGSPSASDIESPNPKLPNSLLDDFLQPPPNSTSSNSLAQSSSSAPRSILDEFVSPSYSQHKENLTPKAPNDS-------------------------------VGETDNSENRKDKLSKDILDDLSSQKPQKPKKSAITKNLLDDFV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*.* *. . . .: .: ** :* :::**:. * :* * .. :.:: ..: * :* :: * : *::* . :* : .: . . ....* . :.:* . : *. : . .:: : * *. :.: *: * *:* * *. . :.**:.:: : *:* .. :.:. :..: * * * * : *:* : .: . : . . : :: :*: .: : .. . : : :. : .: * : :: *.: * : : :*... :: . : : : .: :: :. :* :. : : * *: . : **. ::.:. . *:::*:.. .* .* * : .* .**: ::: : : : *::: .*: . : : : :: . . . .: . :* ::. * : : : * :: .: . .:. : : : . : * .: * . ::...: .* :. .* :: *. . . : : :*::. . . . .: : * *.: . : .:**.*.* *. *:::.. . ::* : : :: :..**: : . . *:::* :**. . :::: :. :: * . :..* ::. : ** *** *:: : .*:: .* :* :*. .: . : . : ** :: *:: . . . . *. . *: * :: ** *: :*: *::: ::* . :: :* *:*:**.:: . ::.: .. **:**: :* ::.: : * * :.:*::: * : .*.:** :.: :.:. .*::**::*** :: .*:: ::**. *:.::* ***.******* **.*:*: .:..****:.**:*.::* :::.*::**: :.*::*.: :** . . * : *: ** ::. ::.:** . . : . :* .* *: . : ** * : .:. : ** **:.::.: : ::*:: .:::: : : . :*.:: . . :::.**. ..* :. . .* * * ::.: :: : :: . : :.: :. :. :. : * *. . * . . :: . : . :.. . . :.*: ", "identical_positions": 191, "similar_positions": 504, "identity": "5.49%" }, { "cls_id": "homologset.agr.MGI:2444631", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LVK0-1", "uniprot_id": "F1LVK0_RAT", "id": "F1LVK0-1", "name": "", "aln": "-----MDQRKNDSIVPSITQLEDFLTEH---------NSNVVWLLVATILSCGWIIYLTYYNSRNVGLILTLVLNRLYKHG---YIHIGSFSFSVLSGKVMVREIYYITEDMSVRIQDGFIIFRWWKMYNPKQKQHDP---------KAETRLYITVNDFEFHVYNRSDLYGRLQELFGLEPTIIPPKKDDDKTRENGRTRTQSKIERVKVKTESQDPTSS-------WRSLIPVIKVNVSTGRLAFGNHYQPQTLCINFDDAFLTYTTKPPSSHLDQFMHIVKGKLENVRVMLVPSPRYVGLQNDEPPRLMGEGFVVMQSNDVDIYYYMDEPGLVPEETEESIEGEISSEDCKLQDLPPCWGLDIVCGKGTDFNYGPWADRQRDCLWKFFFPPDYQVLKVSEIAQPGRPRQILAFELRMNIIADATIDLLFTKNRETNAVHVNVGAGSYLEINIPMTVEESGYTPAIKGQLLHVDATTSMQYRTLLEAEMLAFHINASYPRIWNMPQTWQCELEVYKATYHFIFAQKNFFTDLIQDWSSDNAPDIFSFVPYTWNFKIMFHQFEMIWAANQHNWIDCSTKQQENVYLAACGETLNIDFSLPFTDFVPATCNTRFSLRGEDVDLHLFLPDCHPSKYSLFMLVKNCHPNKMAAEAGVPAECQSGQ-KTVKPKWRNVTQEKAGWVECWTVPSVMLTIDYTWHPIYPQKADEQLKQSLSEMEETMLSVLRPAQKPSERVVSSPSTS-PRPPVDPSELPPDKLHVEMELSPDSQITLYGPLLNAFLCIKENYFGEDDMYMDFEEVISSPVLSLSTSSSSGWTAVGMDS--------DKRENESSAKSIHPLALRPWDITVLVNLYKVHGRLPVHGTTDGPECPAAFLERLCFEMKKGFRETMLQLVLSPLNVFVSDNYQQRPPTDEVLREGHINLSGLQLRAHAMFSAEGLPLGSDSLEYAWLIDVQAGSLTAKVTAPQLACLLEWGQTFVFHVVCREYELERPKSVVICQHGIDRRFCESKLSCIPGPCPTSDDLKYTMTRLAVDGADIYIVEHGCATNIKMGAVRVANCNLHNQSVGEGVSAAVQDFEVRQYIEQLSTCRTGLQPAVLRR-------------------------------------------------------------------AYWLEAGSANLG--LITVDVALAADHHSKHEAQRHFLETHDARTKRLWFLWPDDTLKNKRCR--NKCGCLGGCRFFGGTVTGLDFFKLEELTPSSSS---AFSSTSAESDMYYGQSLLQPGEWIVTKEVPKTVDGNVNGMKRKEWENKSVGIEGERKTQHLSLQVPLRSHSSSSSSEENSSSS-AAQPLLAGEKESPSSVADGPAVQKEFLCGTKRDDGQASIPAEISGTSPVSPNTQDKSVGQSPLRSPLKRQASVCSTRLGSTKSLTAAFYGDKQPVTVGVQFSSDVSRSDENVLDSPKQRRSFGSFPYTPSADSNSFHQYRSMDSSMSMADSEAYFSAAEEFEPISS-----------DEGPGTYPGRKKKKKQ--MQQIDYSRGSIYHSVEGPLTVHGEGITDPRTLPFKTHPSQASFVSALGGEDEVIEHLYIVE------------------------------------------GEKTGDTEQVTSQQPVMSCYQTYLTQFQVVNWS-VKHPTNKRTSKSSLHRPLDLDTPTSEESSSS--FEQLCVPTFKVIKQGLTANSLLDRGMQLSGSTSNTPYTPLDKKIVDNTDDET----LTEEWALDQPVAQTKTTAIVEVKGTVDVVLTPLVAEALDRYIEAMVHCASTRHPAAIVDDLHTKVLREAVQNSKTTFSENLSPKQDIRGSKTEHPMIGTTNQGQTQTNATTKQDSVTIKGLQANVSIPKVNLCLLQASVEESPATVPSRS----VTHVSLVALCFDRIATQVRMNRG----------------VVEETANNVDSSKTSNFDRYVHASKMQPQSSGSLRSNAGAERGKEIAAKLNIHRVHGQLRGLDT-----TDIGTCAITAIPFEKSKVLFTLEELDEFTFVDETD--------QQAIPDVTRIGPSQEKWGWIMFECGLENLTIKGGRQSGAVLYNSFGIMGKTNVTERGGVLT------------------------------SNNSSDSPTGSGYNTDVSDDNLPCDRTSPSSDINGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAP--TNVRSPAHAFSRQLNLLSTATPAVGSWLVPIDQLKSSLNKLDTEGTLRICAVMGCIMTEALENKSVHFPLRSKYN----RLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKGLVALARQWMKFIVVTPAFKGVSLHRPAQPLKPPAAVDHEHEEGLGLDNGGGLQSDTSADGAEFEFDAATVSEHTMLLEGTANRPPP-GGSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPYHSLSYTSGDTATDSPVHVGRAGMPVKESPRKESLLSYLTGSFPSLHNLLEGTPQRS---SAAVKSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNR-GSVVQESPVTKSGHNSLPTGVAPNLPTIPSASDFNTVLSSDQNTLDG----THSQHSTSQDDVAGVEEANQGFPAVQLADAQVVFKPLLSHTGIQSQDTMPLCYRMYFGEHLSFSGTLDCLRADIVDSDTAKDRKGKRARRQGHVNLPPLEFKPALMLETFSISAVVMEKSVCTPQNSTSALSFHDLNKRYYNTFHCNFTISCQSISQHVDMALVR-LIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSSDFSRSSRGSLNGGNRVNNAKNKR------ANSENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDHMTIHMDDSDSITVSEQSEP-------SAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPTEPTCRVVFENEQDSNSLTKTQRKRSLVTAEPQHVTLIVFGIGMVNRTHLEADIGGLTMESELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQ-----------------TVVKCSIAKSQALYSAQRG-LKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQLSKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPIETNEFPQLPEGLEK----------------------------------KPIVLKFSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMSTIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFEHNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTTDGDKP----KILLYSLNLQFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQIVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFDRAVLFWLNYKAAYDNWNEQRMALHKDIHMA---------------TKEVVDMLPGIQQTSAQAFGTLFLQLTVNDLGICLPITNTAQSNHTG----DLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFETSWDDWKPEIRGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVHMDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSP----TIHTSSDGSSVSGDGHKLTFGQRLV------NHLLGLAPPNQRYSVPAEYLCDSEMRGSPQASQAHLKACRAHSWGNEAVDYRRQGTSSSQPGEPRGRKIMKRLVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLGYKPSYS--RSKSISASGRPPLKRMERASSRIGETDELPEIRVDAASPGPRVTFNIQDTLKNTVWGSSPQSSSPGEGYFQFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSPKTTGGFSPSVPFQSEDGRRDDSLSSTSEDSEKDEKDEDREREKFYIYRKPSHTSRKKATGFAAVHQLLTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTT-HLMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASR---GSSLPRTLSKESKLY-----------------------------------AKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPIERNYTAVSSQDEDMGHFDIPDPMEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGSSAPQSGAKTSASKAGMPGSSGLGSPLGRSRHSSSQSDLTGSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKSTVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRSGGASFSESQSVSKSSSKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTVNLPTSGPGTPDSIEGVSQHLSPESSRKAYCRTWDQPSQSASFTHMPQSPNVFSEHMTNNTMSPGTAAAQSLKSPASIRSRSVSDSSVPRRDSISKTSTPVNKSNKAASQQG--TPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGTIDVNALEMVAHISEHPNQQPNHKIQITMGSTESRVDYMGSSILMGIFSNADLKLQDEWKVNFYNALDSSMTD---KSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTVTNNLEKNSQEQ----------------LLDAAHHRHWPGVLKVVSGCHISLFQVPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEWFNYVTATRNEELN---LLRNVDANNSENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLEFKSIHVQEPQEPS----LQDANVKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKCPVIIQDDNSSD----RDREDGITYTT------------------------------------------------------------------------------------VDWRDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKG--------KDKEEH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AAE1-1", "uniprot_id": "BLTP1_MOUSE", "id": "A2AAE1-1", "name": "Bridge-like lipid transfer protein family member 1", "aln": "-----MDQRKNDSIVPSITQLEDFLTEH---------NSNVVWLLVATILSCGWIIYLTYYNSRNVGLILTLVLNRLYKHG---YIHIGSFSFSVLSGKVMVREIYYITEDMSIRIQDGFIIFRWWKMYNPKQKQHDP---------KAETRLYITVNDFEFHVYNRSDLYGRLQELFGLEPTIIPPKKDDDKTRENGRTRTQSKIERVKVKTESQDPTSS-------WRSLIPVIKVNVSTGRLAFGNHYQPQTLCINFDDAFLTYTTKPPSSHLDQFMHIVKGKLENVRVMLVPSPRYVGLQNDEPPRLMGEGFVVLQSNDVDLYYYMDEPGLVPEETEESTEGDISSEDCKLQDLPPCWGLDIVCGKGTDFNYGPWADRQRDCLWKFFFPPDYQVLKVSEIAQPGRPRQILAFELRMNIITDATIDLLFTKNRETNAVHVNVGAGSYLEINIPMTVDENGYTPAIKGQLLHVDATTSMQYRTLLEAEMLAFHINASYPRIWNMPQTWQCELEVYKATYHFIFAQKNFFTDLIQDWSSDNAPDIFSFVPYTWNFKIMFHQFEMIWAANQHNWIDCSTKQQENVYLAACGETLNIDFSLPFTDFVPATCNTRFSLRGEDVDLHLFLPDCHPSKYSLFMLVKNCHPNKMVPETGIPAECQSGQ-KTVKPKWRNVTQEKAGWVECWTVPSVMLTIDYTWHPIYPQKADEQLKQSLSEMEETMLSVLRPAQKTSERVVSSPSMS-PRPPVDPSELPPDKLHVEMELSPDSQITLYGPLLNAFLCIKENYFGEDDMYMDFEEVISSPVLSLSTSSSSGWTAVGMDN--------DKRENESSAKSIHPLALRPWDITVLVNLYKVHGRLPVHGTTDGPECPTAFLERLCFEMKKGFRETMLQLVLSPLNVFVSDNYQQRPPVDEVLREGHINLSGLQLRAHAMFSAEGLPLGSDSLEYAWLIDVQAGSLTAKVTAPQLACLLEWGQTFVFHVVCREYELERPKSVIVCQHGIDRRFCESKLSCIPGPCPTSDDLKYTMTRLAIDGSDIYIVEHGCATNIKMGAVRIANCNLHNQSVGEGISAAIQDFQVRQYIEQLNNCRIGLQPAVLRR-------------------------------------------------------------------AYWLEAGSANLG--LITVDIALAADHHSKHEAQRHFLETHDARTKRLWFLWPDDTLKNKRCR--NKCGCLGGCRFFGGTVTGLDFFKLEELTPSSSS---AFSSTSAESDMYYGQSLLQPGEWIITKEIPKTVDGNVNSMKRKEWENKSVGIEGERKTQHLSLQVPLRSHSSSSSSEENSSSS-AAQPLLAGEKESPSSAADDHSVQKDLLHSARRDDGQASVPTEISGTSPVSPNTQDKSVGQSPLRSPLKRQASVCSTRLGSTKSLTAAFYGDKQPVTVGVQFSSDVSRSDENVLDSPKQRRSFGSFPYTPSADSNSFHQYRSMDSSMSMADSEAYFSAAEEFEPISS-----------DEGPGTYPGRKKKKKQ--MQQIDYSRGSIYHSVEGPLAVHGEGITDPRTLPFKTHPSQASFVSALGGEDEVIEHVYIVE------------------------------------------GEKRGESEQVTSQQPVMSCYHTYLTQFQVINWS-VKHPTNKRTSKSSLHRPLDLDTPTSEESSSS--FEQLCVPTFKVIKQGLTANSLLDRGMQLSGSTSNTPYTPLDKKIVDTTDDET----LTEEWTLDQPVAQTKTTAIVEVKGTVDVVLTPLVAEALDRYIEAMVHRVSTRHPAAIVDDLHTKVLREAVQNSKTTFSENLSPKQDIRGTKTEHPMIGTTNQGQIQTNVTTKQDNVTIKGLQANVSIPKVNLCLLQASVEESPATVPSRS----VTHVSLVALCFDRIATQVRMNRG----------------VVEETANNVDAGKTSNFDRYVHASKMQPQSSGSLRSNAGAEKGKEIAAKLNIHRVHGQLRGLDT-----TDIGTCAITAIPFEKSKVLFTLEELDEFTFVDETD--------QQAIPDVTRIGPSQEKWGWIMFECGLENLTIKGGRQSGAVLYNSFGIMGKNSVTERGGVLT------------------------------SNNSSDSPTGSGYNTDVSDDNLPCDRTSPSSDINGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAP--TNVRSPAHAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSVHFPLRSKYN----RLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKGLVALARQWMKFIVVTPAFKGVSLHRPAQPLKPPATVDQEHEEGLGLDNGGGLQSDTSADGAEFEFDAATVSEHTMLLEGTANRPPP-GSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPYHSLSYTSGDTATDSPVHVGRAGMPVKESPRKESLLSYLTGSFPSLHNLLEGTPQRS---SAAVKSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNR-GSVVQESPVTKSGHNSLPTGVAPNLPTIPSASDFNTVLSSDQNTLDG----THSQHSTSQDDVAGVEEANQGFPAVQLADAQVVFKPLLSHTGIQSQDTMPLCYRMYFGEHLSFSGTLDCLRADIVDSDTAKDRKGKRARRQGHVNLPPLEFKPALMLETFSISAVVMEKSVCTPQNSTSALSFHDLNKRYYNTFHCNFTISCQSISQHVDMALVR-LIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSSDFSRSSRGSLNGGNRVNNAKNKR------ANNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDHMTIHMDDSDSITVSEQSEP-------SAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPTEPTCRVVFENEQDNNSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMESELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTAKQEFLTVVKCSIAKSQALYSAQRG-LKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQLSKQISDLIRQPSTAPQPMKEDIATPLPSEKTPTSVNQTPIETNEFPQLPEGLEK----------------------------------KPIVLKFSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMSTIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFEHNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTTDGDKP----KILLYSLNLQFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQIVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFDRAVLFWLNYKAAYDNWNEQRMALHKDIHMA---------------TKEVVDMLPGIQQTSAQAFGTLFLQLTVNDLGICLPITNTAQSNHTG----DLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFETSWDDWKPEIRGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVHMDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSP----TIHT-------------------------------------------------------------------------EAVDYRRQGTSSSQPGELRGRKIMKRLVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLGYKPSYS--RSKSISASGRPPLKRMERASSRIGETDELPEIRVDAASPGPRVTFNIQDT---------------------FPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSPKTTGGFSPSVPFQSEDGRRDDSLSSTSEDSEKDEKDEDRERERFYIYRKPSHTSRKKATGFAAVHQLLTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTT-HLMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASR---GSSLPRTLSKESKLYGMKDSAASPSPSPLPCTVQSKTNTLLPPQPPPIPSAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPIERNYTAVSSQDEDMGHFDIPDPMEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETVSPGSNAPQTGAKTSASKAGMPGSSGLGSPLGRSRHSSSQSDLTGSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKSTVSGLTSGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRSGGASFFESQSVSKSTSKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTVNLPTSGPGTPDSIEGVSQHLSPESSRKAYCRTWDQPSQSASFTHMPQSPNVFNEHMTNNTMSPG-TAAQSLKSPASIRSRSVSDSSVPRRDSISKTSTPVNKSNKAASQQG--TPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGTIDVNALEMVAHISEHPNQQPNHKIQITMGSTESRVDYMGSSILMGIFSNADLKLQDEWKVNLYNALDSSMTD---KSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTNNLEKNSQEQ----------------LLDAAHHRHWPGVLKVVSGCHISLFQVPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEWFNYVTATRNEELN---LLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLEFKSIHVQEPQEPS----LQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKCPLIIHDDSSSD----RDREDSITYTT------------------------------------------------------------------------------------VDWRDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKG--------KDKEEH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2LD37-1", "uniprot_id": "BLTP1_HUMAN", "id": "Q2LD37-1", "name": "Bridge-like lipid transfer protein family member 1", "aln": "-----MDQRKNESIVPSITQLEDFLTEH---------NSNVVWLLVATILSCGWIIYLTYYNSRNVGLILTLVLNRLYKHG---YIHIGSFSFSVLSGKVMVREIYYITEDMSIRIQDGFIIFRWWKMYNPKQKQHDP---------KAETRLYITVNDFEFHVYNRSDLYGRLQELFGLEPTIIPPKKDDDKTREIGRTRTQSKIERVKVKTESQDPTSS-------WRSLIPVIKVNVSTGRLAFGNHYQPQTLCINFDDAFLTYTTKPPSSHLDQFMHIVKGKLENVRVMLVPSPRYVGLQNDEPPRLMGEGFVVMQSNDVDIYYYMDEPGLVPEETEENIEGEMSSEDCKLQDLPPCWGLDIVCGKGTDFNYGPWADRQRDCLWKFFFPPDYQVLKVSEIAQPGRPRQILAFELRMNIIADATIDLLFTKNRETNAVHVNVGAGSYLEINIPMTVEENGYTPAIKGQLLHVDATTSMQYRTLLEAEMLAFHINASYPRIWNMPQTWQCELEVYKATYHFIFAQKNFFTDLIQDWSSDSPPDIFSFVPYTWNFKIMFHQFEMIWAANQHNWIDCSTKQQENVYLAACGETLNIDFSLPFTDFVPATCNTKFSLRGEDVDLHLFLPDCHPSKYSLFMLVKNCHPNKMIHDTGIPAECQSGQ-KTVKPKWRNVTQEKSGWVECWTVPSVMLTIDYTWHPIYPQKADEQLKQSLSEMEETMLSVLRPSQKTSDRVVSSPSTS-SRPPIDPSELPPDKLHVEMELSPDSQITLYGPLLNAFLCIKENYFGEDDMYMDFEEVISSPVLSLSTSSSSGWTAVGMEN--------DKKENEGSAKSIHPLALRPWDITVLVNLYKVHGRLPVHGTTDGPECPTAFLERLCFEMKKGFRETMLQLILSPLNVFVSDNYQQRPPVDEVLREGHINLSGLQLRAHAMFSAEGLPLGSDSLEYAWLIDVQAGSLTAKVTAPQLACLLEWGQTFVFHVVCREYELERPKSVIICQHGIDRRFCESKLSCIPGPCPTSDDLKYTMIRLAVDGADIYIVEHGCATNIKMGAIRVANCNLHNQSVGEGISAAIQDFQVRQYIEQLNNCRIGLQPAVLRR-------------------------------------------------------------------AYWLEAGSANLG--LITVDIALAADHHSKHEAQRHFLETHDARTKRLWFLWPDDILKNKRCR--NKCGCLGGCRFFGGTVTGLDFFKLEELTPSSSS---AFSSTSAESDMYYGQSLLQPGEWIITKEIPKIIDGNVNGMKRKEWENKSVGIEVERKTQHLSLQVPLRSHSSSSSSEENSSSS-AAQPLLAGEKESPSSVADDHLVQKEFLHGTKRDDGQASIPTEISGNSPVSPNTQDKSVGQSPLRSPLKRQASVCSTRLGSTKSLTAAFYGDKQPVTVGVQFSSDVSRSDENVLDSPKQRRSFGSFPYTPSADSNSFHQYRSMDSSMSMADSEAYFSAAEEFEPISS-----------DEGPGTYPGRKKKKKQ--TQQIDYSRGSIYHSVEGPLTGHGESIQDSRTLPFKTHPSQASFVSALGGEDDVIEHLYIVE------------------------------------------GEKTVESEQITPQQPVMNCYQTYLTQFQVINWS-VKHPTNKRTSKSSLHRPLDLDTPTSEESSSS--FEQLSVPTFKVIKQGLTANSLLDRGMQLSGSTSNTPYTPLEKKLADNTDDET----LTEEWTLDQPVSQTRTTAIVEVKGTVDIVLTPLVAEALDRYIEAMVHCASTRHPAAIVDDLHAKVLREAVQNSKTTFSENLSSKQDIRGTKTEQSTIGTTNQGQAQTNLTMKQDNVTIKGLQTNVSIPKVNLCLLQASVEESPTTAPSRS----VTHVSLVALCFDRIATQVRMNRG----------------VVEETSNNAEPGRTSNFDRYVHATKMQPQSSGSLRSNAGAEKGKEIAAKLNIHRVHGQLRGLDT-----TDIGTCAITAIPFEKSKVLFTLEELDEFTFVDETD--------QQAVPDVTRIGPSQEKWGWIMFECGLENLTIKGGRQSGAVLYNSFGIMGKASDTERGGVLT------------------------------SNNSSDSPTGSGYNTDVSDDNLPCDRTSPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAP--TNVRSHTHAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSVHFPLRSKYN----RLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKGLVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADGAEFEFDAATVSEHTMLLEGTANRPPP-GSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPYHSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRS---SAAVKSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNR-GSVLQESPVTKSGHNSLPTGVAPNLPTIPSASDFNTVLSSDQNTLDG----THSQHSTSQDDVAGVEEANQGFPAVQLADAQVVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQGHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTISCQSISQHVDMALVR-LIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSSDFSRSSRGSLNGGNRVNNAKNKR------TNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDHMTIHMDDSDSITVSEQSEP-------SAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPTEPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMESELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTAKQEFLTVVKCSIAKSQALYSAQRG-LKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQLSKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEK----------------------------------KPIVLKFSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMSTIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFEHNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKP----KILLYSLNLQFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQIVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFDRAVLFWLNYKAAYDNWNEQRMALHKDIHMA---------------TKEVVDMLPGIQQTSAQAFGTLFLQLTVNDLGICLPITNTAQSNHTG----DLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFETSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVHMDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSP----TIHT-------------------------------------------------------------------------EATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYS--RSKSISASGRPPLKRMERASSRVGETEELPEIRVDAASPGPRVTFNIQDT---------------------FPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTT-HLMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASR---GSSLPRTLSKESKLYGMKDSATSPPSPPLPSTVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPG-TVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQG--TPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSSITD---KSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQ----------------LLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEWFNYVTATRNEELN---LLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEPS----LQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSD----KDREDSITYTT------------------------------------------------------------------------------------VDWRDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKG--------KDKEEH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXZ1-1", "uniprot_id": "A0A8M9PXZ1_DANRE", "id": "A0A8M9PXZ1-1", "name": "", "aln": "-----MDKGNNS--LPTYDEIDEYLSRR---------NSTFVWLLVATIMSCGWIIYLTYYNSRNIGLVLTLIINRLYKNG---YIHIGSFSFSVLSGKVMFRDVYFINKDMSIRIQDGLLIFRWWKMYNPKQKQHDP---------KAETRLYVTVNGFEFHVYNRTDLYTRLQEIFGLEPTLIQSNRDEEKGRE----QRDKSLESVHIKAETQDPSSS-------WRSLIPVIKVNISTGRVAFGNHHLPQTLCMNFDDAFLTYATKPPSSHLDQFMHIVKGSLENVRVMLVPSPRYLGLQNDEPPRLMGEGFVVMQSNDVDIYYYQDEPGLVPEELEN-GDTEACSEDAKLQDLPPCWGLDIVCGKGTDFNYGPWADRQRDSLWKFFLPADYQPMKVSEVPTPGKPRQILAFELRMNIIADATIDLLFTKNRETNAVHVNVGAGSYLEVNIPMTVGENGYSPTVKGQLLHVDTTSSMQYRTLLEAEMLAFHVIASYPRVWNMPQSWQCEIEVYKATYHFIYAQKNFFTDLIQDWASDSEPDIYSFVPYSWKFKILFHQFEMIWAANQHNWIDCSTKQQENVYLAACGETLNIDFTLPFHEFVPVTCNTRFCLRAEDTDMRLCLPDCHPSRYPLLTLAKDYQHSKSPPDNNMPAEGQGAPPKNSKPRWRNMTHAEAGWVDCWSVPNFMLIIDYTWHPIYPQKSEQQLKQSLSEIEESMLSALRPPE-----LAPPVPPP-PRVSSDPSLLPPDRLHVEMELSPGSHITLYGPLLRALVSIKENYFGEDDMYTDFEESLSSPVLSTCSSSS-CWTGVGLE-------------DKSSKEAPHPLTLRPWDITVFINLHKVHGRLPTHCSSDGPEGPTGFMERLCFEMKKGYKETMLQLVLSPVHVFVSDNYQ-RPPIDAVLRDGHLSLSGLQMRAHAMFSAEGLPAGSDTLEYAWLIDVQAGALTGRVSVPQCASLLEWGESFVFHVMSREFQLEQPKPSVTCQHGVDRRICDAKHAGLPGHCRTSEDLKYTMTRLTVDGAHIFVVEHGCAANIKTGALRVATCNLHTAAVGEGISAVLQDVVIAQFIEQQEVARLGLPPPLLRR-------------------------------------------------------------------SHWLEAGSVTFN--LITADVALAADHSAKYEVQRQFLELHDMKTKRLWFLWPEE--KYKRSR--NRCGCLGGCRFFGGTIGGLDFFRLEEITPSSSS---AFSGISAECDMSYGQSLLHPGEWIVTKETPKIPDAKGIAVRRDTCSPAPVVDLERRVQQHLSLHVPQRSHSSASSSEENSSSS-AALPLLAGERESPS------------------------PSTELMNVTTDCPIPEGPPLR-SPLRSPLKRQSSVQSARLGSTKSLSAAVFVEKALPPAGVQFSSEVSRSDENVLDSPRQRRSYGSFPFTPSADSSTFHQYRSVDSSMSVADSEAYFSATEEFEPISS-----------DEGPGTYPGRKRRRRQQGQPHTEHSRTSIYHSVEGPLSIN-----EIRPPLLPSHTSQASFVSALG-----LEEEGSIE------------------------------------------TEK-ADPGILTTQPHLMACYQNYLAHYHVSNWA-VKQPTNKRTSKSSLHRPLDLDTPTSEESSTC--FDQLSIPTFKMVKAGLSASSLLDRGVQLMGDINSTPYTPLDKRAMDNTDEDT----VTEDWTVDQPLAQTRTTAIVEVKGAVNVVLTPLVVEALDRYIESMVHFASFRHPASILDDLHGKVLNEVYQISKSTVSESSAAKQEHKISKTEGTTPGSLSTPHGQTDLSIKPDNVKIKGLQANVTVPKVNLCVLQASVEES--SPSNKS----ITHVSLVALCFDRIATQLRMNRG----------------IVEDTEK-----PSVMMEKFSSASKMAPQSSGSLRSNAGIEKGKEIAARLNIHRIHSQLRGLDS-----SDIGACAITAIPFEKSKVLFSLEEIDDFVLVDETEPSISTEHMPEHNPDHSRLGTSPEKWGWIMFECGIENLTVKGGRQSGAVLYSAFGVMGGADSGVRDGVSK------------------------------SNDSSGSQTGSGYSTDVSDDNLPNDAQSPASEPNNNSDSDEQDEGVESDDLKKDLPLLPPPPDSSSMKLTIKEIWFSFAAP--TNIRSHAPVMSRQLNLLSTATPAVGAWLVPIDQLKSSLEKLDMEATLRVCAVMGCIMTEALEKKSIHIPFRSKYN----RVTKRARYLHENPSCLLCNILHRYLQQADYTIIEEATMNDGLPALVTLRKGLVALARQWMKFIVVTQGFKAVGLP--QQLPKPKEQEPVEPEQTPGLDCGGALQSDTSADGAEFEFDAGTVSEHTMLLEGVCSRPAPTGNSAPVTGVEIMRKLSKSHTHSESALRIKGSHPYQSLSYTSGDTAADSPAHVSRTGLQCNHSPRKESLLSYLTGSIHSLHNLLEATPHRANE-QTATKSSSLTRTGNSVGADVLTEHPLLSEPFSVSFYNWMSNAVGNRTGGNVQDSPLNRSQHNSLQTGGV--LPTIPSASDFNTVLSSDQNTLDTHSQHSHSQHSTSQEDLLDQDETNLCPAAVQLADAQVVFKPLLSHIGIQPQDAPPLSYKMYFGEHLSFSGTLECLRADIVDSDTSKERKNKRAHRQGMVNLPPLDFKPALMIETFSLNAVVLEKCMSTPP-SASALSFHELSRRPQASVHCHFTVACQAIRQHVDMALVR-LIHQFSTMIDDIKATQTDIKLNRYTAGSSSPTPT-KGRPYREFRSSDFSRSSRGSLNGAARLGTQKGKRGMVGPGLDTLTRSREPRGRGTLGRSERRTSKVSRKGSRDVADHMTIQMDDSDSITVSEQSEP-------SAECWQNMYKLLNFYSLISDPTGILEKNQDNALSEGGRSPADPPCRVVFESEEE-TPPSRLGRRRSLVSAEPQHVTLIVFGVGMVNRTHLEADIGGLTMEAELKKIHGSFTLKEKMKDILHQKMTETCASAHIGCVNIVLLEGISPDIQ-----------------TVVKCNIAKSQALYSAQRG-LKTNNAAIFKVGAIFINIPQHPATLHSMMVRSSHQLSKQISDLIRQPSNTPPPNREDTPTPQPSE---VSINQTPVEANEFPQLPEGLEK----------------------------------KPIVLKFSAMLDGITIGAALLPSLKAEYKMGRMKSHGMTGAQTRFTFELPNHKLCFQSKVSPVDVSAMPPTASLTLPPVTMSGQYIIQEHEGHSDTAWAPEYSS-----YLQGNYLRCVAEIGSFEHNLTTDLLNHLVFLQKVFMKEVNEVIQKVSGGEQPIPLWNEHDVSTDGDKP----KILLYSINLTFKGIQMTATTPSMRAVRFETGWIELELSNRVQCKTTPTGSNYLKLFGKCQVDLNLALGQIVKHQVYEEAGSDFHQVAYFRTRIGLRNALQEEISGSSDKEAVLITLSRPIIFAQPVAFDRAVLFWLNYKAAYDNWKEQRLALNSDIHMA---------------TKEVVDKLPAIQQTSVQAFSTLFLQLTVNDLGICLPITSATQANYSI----DFDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFAEGFETTWDDWKPEIRGDLVMNACVVPDGTYEVCSRTTGQASAESSSAGTWTLNVLWKMCGIDVHMDPNIGKRLNALGNTLTSLTGEEDNDDITDLNSVNMADLSDEDESDGMSP----PVHMFAEGDLSPRVSFRKRLVQSILGISPSPPPLSPSECRSVSPSSTITRLKSRSVRLPSSANAERTRHPRPLSWGCESVDLRRQAVMSNQIIDARGRKFSKRLVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLGYKPSYSNSRSKSISAAGRPPMKRSDRPR------EDLPDIKVEAASPAPRVTFNIDMDSTN---------PSPADSVFKFPEETEMELLSVTIDDAAHYP-----SCSVFSAPGTPAVFSPTVPFQPDDSRRDDLSSTSSEDTDK-EDDFDRDRPQSY-YRRPGGSQRK-----SALSALFSERWPATPPQRGGLAPPTERNIDFELDVRVEIDSGKCVLHPSTQPTEHEDLALRRSCERSSRSLDQDSPPKKRKVQPSFPSSS-HLLSAKRVPTSLQSKSSDIETTVFYIPGVDVKLHYNSKTLKTESPNASR---GSSLPRTLSKESKLYGMRDAPTPAPAP--AASGPGKTNTLLSPPPPPLPSAKGKAGVGVKTAKLYAWVALQTLPEEMVISPCLLDFLEKALETIPITPVDRNYTTLNVHEEDVGHFDSVEPLEESQVSLVSSATSPYSSFPVDVVVYVRVQPSQIRFSCLPMSRVECMLKLPSLDLVFSSNRGELEPTSATYPSEGQHTPSSTPPSVHNANRVPGGKGPSTGLGSPLGRSRHHSSQSDLTGPPINSSGLSFTACMSDFSLYVFHPYGAGKQKSAVTGLPPGPGPLGSVEDEASSVTGRKDSLSINLEFVKVSLSRMRRTGCPAFIDTFIASKG-GKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLPASGPATPDSVESIAQHLSPESSRKAYWRTWDG------QTTQHPSSSVFTDTTP---------SHSHLKSPATGRTRSVSDSSAPRRDSVTKTSTPSFRNGKAAAQQG--SPWETLVVFAINLKQLNVQMNMSNVMGNNTWTTSGLKSQGRLSVGSNRDREISMSIGLGRSKLDSKGGVVGGNIDVNTLEMVSHISEHPNQQPSHKIQITMGSTEARLDYMGSSILMGIFSNADLQLQDEWKVNLC-TAEASLSE---KSEIFVHGDLQWDIFQVIISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPYMPPKTPVINTDKASAEL----------------YMDAAHHRHWPNVLKMVAGCHISLFQMPLPEDAVQLGGSMSLHGNHMTLACFHGPNFRSKSWVLFHLEEPNIAFWTEAQKIWEDGCSDDSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKVTRRRHENPPHGVATVKEWFNYVTAMRNEELN---LLRNVDANNSESGAAAKSSSLLSGFRGSSSYNHETETIFALPKMQLQFKSIHVQDPEEPS----LSDANSKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKALFAPRMFASRPGQKSPTTQQDEPSSDKKEEREKEEGVNYTT------------------------------------------------------------------------------------VDWREFLCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEREKKGQ-------RDKDEH-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JA38-1", "uniprot_id": "X2JA38_DROME", "id": "X2JA38-1", "name": "", "aln": "MEALEVEDTSDDSLPMGFPEVGTWNSTHNVSLNDMNLDARMIWLLASLLTTITWVTYITFYNSRVIGMLITKIANRWFIKGA--YFKIGSVALNPLAGKIMFRDFVYITYDYTVRAQDGYFIFRWWRSYVPKDVSEDLS--------HSDTRLSVQLNGYELHIYNRSDLYDTLEKTFGLEPSLLIPTDAASNEERNKLKEHHMNLENARQSQRIQNVKNSEAMQATTWRDLIPVIKIDVCSGRFVFGNRLTPTTLSISVEEAHCTYSTKPAVCRLDHFMHFVKAKVENAKVLFCPSPKYTGLID-EPPRYMGEGFVVMMSNQMDLYFYMDEPGVVPEHPVQIVLPNGD----VVEPSPPVWGINARCLRGTDFSYGPWADRQRDHLYRYFYPSDWKEAEVTPTPQPGELRSYQSFDVTLCVLNEATIDILFSKEKETNAMHITVGPASYVEMTIPWVTQPDGYTSKIQGQLFHVEATTSLQYRSLAEFESLEYKVRIHYPTKWNAPQDWSISLSGCKTSAFIVYKHKCFFQDLIEDWANKARPDILSFVPYTCNFSIRLHEFEILMLCNEYNWIDCSSANQENNHLAFCGDVFEMSFALPFDDFLPKTVTLKFWIHGEGLDLSLYVPEVSSVRPIVLAIDENARLLTREGKLIRRPE-------LYSKKWRKICQRSAGWIDCWAVPILALSIQYVYHPVPPLGPDPQADITTPEKEEILLSPMRIPKVRKSPVSSWQQPPEQYSKFDPGTLAADHVTVELEIG-SSVLMAYGNVLRNFISLKENIFGEDQNFTDMEQSNVNMKEPGVAQVNPKDQLLAKEKELANKSISETQPPEEKRKPFDPRLYRPLEVMVSVIVHDIQAHVMKNCNEDDPPCPVVLIERFGFEMNKKYHETTLQVLVSPSYLLTSDCLQ-RSQREQHINQGHLMLSAVQVRGHAMFSNEGCALDEDTLEYSWLVEVQLGKLTGKLTLPQLVNVVTGLETLILLAIDPENCLKSPKTVRNCHHGVPSNLCPQTKEEKKYKCPSSEDIKYKMTRVSVDAVDVYLIESGTALHAWISPIRLANCNLHGQRVKSGISGLLPSILLRLFMLHTTNSTFNTNTTGSNRSGKLRRADQDSLKSQDAGGSHYASHGKTGKRSSNSFSRRDSREEATRKLRGSFSETHTKRTPETEITENWVEVGCTSLGPILLEGASALPIPDHELHLVQHNFLREHDAKFKRLWFLWSNNGSALSSGSEISRCGCIGGCAFFGSNRNGQKFFKPTAQDAHDNYNIARYFIINNNKDFGFGESILHQGQLVFHTPPYSLHCVSLYDTADFNGKGRLYRPAGDLRNGSLKKTDLCSLPDGTKFKIGASGTTGVEKPEPNCRNKSRESIGSPNTLERRTKRYPCTRQTSVDVPYARLLDSPSKKLQLQHEASAGDAGSSHRRGSDSNRLRVSPPKTSISDSRLTGDVLDDETEIPDEMSHSAPHSHPLEFEIADIALHVQGLGGDQLPREVQRTIS-LTSENPSEMFFSAEEDISNVLSQRGSMKQRNSVNSGSVVLSGKKRFSSDLSIGAQNDNGSHTLPTYRSDLEIHAPDGNKTLPKRPQSTTELNEDARRIHGLATPIRKITNISSRPEYRHFVHDADSRGSSSGTPSLSSNSFISAMSSQEDVALVNLHQQVNRPIIDSPLLMASYLNHLSQVKCFNWNGCSFPLGPDVFSTPLFSENEDGGLTYIGSKMLPHFDLYSCWREIKVVPRYENATGSNSSATFMGGPKSHPWDPSVLLKEEESDKTTNGFDDGEFMSLQAEGGAVCTSVVARLKGQLNVFLTPLLLEGLQRMVEAAVPTIQSMHLLSVVNFIHTSCIAKVNNDNILKRDQSLSYWSQVHSN-SKRSTTERHLQGPGDSFLSDVYEESISTKTQGLIVLPKVSITMLQSSIVEEIISVAALDNVQDLSCVSLLTFYMEGISTKFHMGKTTRASMHNVYIQQTVQSGSSNKKGGIMKGTRALLAHLSSQTRPDNVQGEPILIETSEKQLEEVVITLDIGRAHAQLRRLKTEGQSCTQDSPIIVTAIPEHKSKVLFECLKMPESTGIESIGYIMFECGLEGVGVKIVKRSHFEKSENSKEELAEMAGAGAGGGASAGGFNLNDLVGQGEGAAGSGDGGATSKAEAAWRLITKKPPTPKTPKEKFQPASDSNISAETSGAEKGKSTPKPPDEDVEKGTSPANAQTGAQKPSAGAGTNTKDNYDKVLSNVKETDKTSSCVIELKAVWFNFAAPPCVPITRKIDLTRLDWNLLSTASPAITAWMNPSNRLAMKIVSLMKALHTRQTAVAACLMAEAMDNEKIQRNPKIKKSRYANNYTLLSKTLQEDPSCQLCYIMQKLVLDEGVQRIETIFKQHDVPHLNTLRQGIIVLSRQWKNTLYNPILFEHQYKNKLSRPINVTFSFPQNEEDAENDECEGDVEMGAFAGVGENPEESENALLLGQTQHHRTHIGATYGHEGANHGTASQRSTSTSPNIHHPRRGLNKVHSKASN-YSHGNSSRSSIQMLPIISGQVPEFEYGALQEGSLSSTNSVNKSWLGTENHKEDLYFWMAKQQDNKKKHFTEKEHARPAPPKMTEHAGQTRSGIMQDSIKLLDAHLIFEPLLTCLGVMPQQMINKFSNADISSLENFGTNLS------------LIGTFDSIRVDIVVSEAGDKKNSAQKPAKLNKKSNGGRASIMMDTPLFLCERVGVELEVLKMSDGMVDQARQNVIYMSRRQLKKHTSTVINFSLNVRFISQQVNMPLLRLLHQICNMYQNVKDAQNEFHDQ--PELSKKSQTKDECSLASEPTDIVPFNSMSERYNHAENYSDERYDKFNETMPTMLARPRPGGLAPIIQLTPSPNAKNRPQSFAQKLRSTGKSVKGKLGYTNLN---------ESSSSPLRDSPTMSLHEHNILKMSTESKASLNGACATSVSGDYQNTLTKAGMPTMAPMLETPNCWKTIYHLLELYGTMPETKTVVQRSS----LNEHKSKSAGFAHDDDDLASAPTPLPQHREMLLVDASSQERTRLIVFGVAKIHKTRLLATLSGLKLESEITTLNSTATWRKKARPVS----LECSLTGQVGRAMIVLLEGVAPSQQ-----------------TVVKVTVGKSQTLYSSLSKRGKDKNSGLLSIGAVNIDIPQHPVALHGMMTRSSKQLSSTLQELRVKRNSGRSTMRSHTAEEPESPFHARNSVGASSGTGVASEMRERTVSGGAGAQQQPQQAARRAAHMAQSKTGTAQHQNGLLQPLVMQFNVLLQSLSINAALLPSLQAQYRMNHVSSMGVTGQRAKFVIDLPTHTLSFNTKIQNEMN--LPSEACIGLPPVHVLAEYIPDHRQDHTENVEGIVLRQ--------GGYVNASAEIGEFERCLTTDLLNHLVFVQKVFMREINEVLQKVYGGEKPVPLWTEESGDSSGAVQESSLKRILFSINISMKRIQLTATTPCSSAVRFETGILELQLSNRVKNLG---DMSNRKLFFKAHIDFNLSLGQIIRNVIFDEAEPEFQQYAFFHTTINLRNAFQDELLNE-DKELILLTLKRPLVYVQPIAVDKAILVWLNYKNAYEYWAEKRANLCHEHAQHSLLSQYSGQHQNQNMQNPQVFDRVAFGQIAGSNLSTLFLQLTVEDMGICLPLKQVNTTTFGSRSYQDFDAKGAVVITLENTIISACNSGALVSKGKFQGLCLRFADDFETNLDDWKPNS-AEPIMNVCVVSEGTFEVCSRTT---AAKKGENAKWLLNVKWQMEGVDIHLDVNIGKQLSSLGHTLTMLTGFEEDETQMESPDSDEGDQSCRDTFVRRRGDFDN---------------------------------------------------------------------------------------LPAFVFDPTIDSKKRSFMMEKEMAEQLKIINDLRTLGASHNTVAHEERRLQELQAICYKYFRRDMIQKWKRPSLRRSLKTYGRSHSYIGSGS-----SVSGVG-------------------VPQTLDNVSYTGRRLDTIASN-----------------------------DEISSLQSTPASCHSRSASLKHTTGGGVIGGGVNALGRVTFTEAMRQTSLPNADTDTETADNELDWRG------------------DITPSEIDVDGTSVEMRRKHGHGQKQPEPNIDFELDIKVLVNSGKCVLHTKDTGEERGYAGGSGAATSGVPASSVKSHKREKSIGNDWGSPTPSRRQRDKSKLRYNANALLADLTIFHIPGLDVKLHYQSKTLAEQLTGDQL---PTGR---------------------------------------------------RMGSKRATLCAWMTLQSIPEETIISPHILEFLEQTLEPIPARQSSSVPPTPSHNTG-------------VNLDILPANYVTYASFPVDVIVYFHMQPSTFRFSCLPVSRVECMLQLPSLDIVFSSKRSSEEENSAQPGGHTQ------------------------------------------PDQQLPTGGLSVTGCLADFNVFIFHPYGGKKTS-------------KETQFSPLSDSERKDSLSINVEFVKFHITRCR----KVYIEPLPSSKRSLDQSRAVIRFSTIVDIGSASFKYDMRRLTEILAFPKAWYRRRIVRRLFLGDLSVQQQQQQQQGNGAETPTGCPPATPTPNEDASRAKDN-------------------------------MRLDFDGQPSQQQQQLGHFGAVRHLKNLGKSSSAESSGTPPSEKNQITAWETLVIFAVNFTKLNVQMNIGNVCGNVVWLTKDFQSDGRLSIGSTGYKNMYAGIYLGGSALDAKGGIVGGSFEVNKINKRFHIKEEAGMEPYHTMGLSFMALELRLDYMGTSVLMTRISSFSAAMKDEWRTASQAAATPAHGKDQPRALIFIHGDLTWDQLQIMISKSTTADLLKMYFKLEEFFTQQFKSSKRVFSNLEPRLQDRTASIKRRQQHKKKPANGELVAPPQIHGMIGENTDARHHRHWQKPLAQAVGLVVPSLVTRLPRHGNVLGGTVELRGQNISLACFHGINFKSKSWALFSLRSPSINFATEAR------QSEDEVLVTQTLTSSLGQTTEVQQQQ---NHSMAIVSRITRN--IIFPPQFKTLNEWFHYAFANSEIDAVDRFPMLECEREIASNSIERTRASGSSSAAKAQEHNHNREVIFALPSLQLHFKTEHKQGPTTPEPSVLCSIAENKPEVLCSFITEFDDHIFVTVDADAFFFLHDLITSYVTEKEKVIGAQSARAASPNLSQKANLKPYLTDEILKEKKGASNTNLTAQGKQTSGSKNSLDPLQGSHTSLANAAANMSGAATTNTTTTTTATTLSPGAAAGGPSTSATNDSVDGKQQQQEGSPPTFDLESFVRDWRHFECQTWHLEPTVRLLSWAGKSIEPYGVDYILNKLGFSHARTTIPKWLQRGFMDPLDKVQALMMLQLLLMVRENKVERDSGASGSGKQQQQNHRPPTN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12150-1", "uniprot_id": "CSF1_YEAST", "id": "Q12150-1", "name": "Protein CSF1", "aln": "--------------MEAISQLRGVPLTH--------QKDFSWVFLVDWILTVVVCLTMIFYMGRIYAYLVSFILEWLLWKRAKIKINVETLRVSLLGGRIHFKNLSVIHKDYTISVLEGSLTWKYWLLNCRKAELIENNKSSSGKKAKLPCKISVECEGLEIFIYNRTVAYDNVINLLSKD-------------------------ERDKFEKYLNEHSFP-----------------------EPFSDGSSADKLDEDLSESAYTTNSDASIVNDRDYQETDIGKHPKLLMFLPIELKFS-----RGSLLLGNKFTPS----VMILSYESGKGIIDVLPPK----------------------------------------ERLDLYRNKTQMEFKNFEISIKQNIG---------------YDDAIGLKFKIDRGKVSKLWKTFVRVFQIVTKPVVPKKTKKSAGTSDDNFYHKWKGLSLYKASAGDAKASDLDDVEFDLTNHEYAKFTSILKCPKVTIAYDVDVPGVVP-------HGAHPTIPDIDGPDVGNNGAPPDFALDVQIHGGSICYGPWAQRQVSHLQRVLSPVVSRTAKPIKKLPPGSRRIYTLFR-----MNISIMEDTTWRIPTRESSKDPEFLKHYKETN-------------------EEYRPFGWMDLRFCKDTYANFNISVCPTVQG-------------------------------------------------FQNNFHVHFLETEIRSSVNHDILLKSKVFDIDGDIGYPLGWNSKAIWIINMK----------------------------------SEQLEAFLLREHITLVADTLSDFS---------AGDPTPYELFRPFVYKVNWEMEGYSIYLNVN---------------------DHNIVNNPLDFNENCYLSLHGDKLSIDVTVPRESILGTYTDMSYEISTPMFRMMLNTPPWNTLNEFMKHKEVG--------------RAYDFTIKGSYLLYSELDIDNVDTLVIECNSKSTVLHCYGFVMRYLTNVKMNYFGEFFNFVTSEEYTGVLGAREVGDVTTKSSVADLASTVDSGYQ-------------------------------------------------------------------------------------NSSLKNESEDKGPMKRSDLKRTTNETDIWFTFSVWDGALILPET---------------------------------------IYSFDPCIALHFAELVVDFRSCNYYMDIMAVLNG--------------TSIKRHVSKQINEVFDFIRRNNGAD-----------------------------------------------------------------------EQEHGLLSDLTIHGHRMYGLPPTEPTYFCQWDINLGDLCIDSDIEFIKGFFNSFYKIGFGYNDLENILLYDTETINDMTSLTVHVEKIR-------------------------------------------------------------------------------------------------------------------------------------------------------IGLKDPVMKSQSVISAESILFTLIDFENEK---YSQRIDVKIPKLTISLNCVMGDGVDTSFLKFETKLRFTNFEQYKDIDKKRSEQRRYITIHDSPYHRCPFLLPLFYQDSDTYQN-------------------LYGAIAPSSSIPTLPLPTLPDTIDYIIEDIVG--------------EYATLLETTNPFKNIFAETPSTMEPSRASFSEDDNDEEADPSSFKPVAFTEDRNHERDNYVVDVSYILLDVDPLLFIFAKSLLEQLYSEN---------------------------------------------------------------MVQVLDDIEIGIVKRLSNLQEGITSISNIDIHIAYLNLIWQETG----EEGFELYLDRIDYQMSEKSLEKNRTNKLLEVAALA---------------------------------------------------------------------------------------------------KVKTVRVTVNQKKNPDLSEDRPPALSLGIEGFEVWSSTEDRQVNSLN----------------LTSSDITIDESQMEWLFEYCSDQGNLIQEVCTSFNSIQNTRSNSKTELISKLTAASEYYQISHDPYVITKPAFIMRLSKGHVRENRSWKIITRLR-----------------------HILTYLPDDWQSNIDEVLKEKKYTSAKDAKNIFMSVFSTWRNWEFSDVARSYIYGKLFTAENE---KHKQNLIKKLLKCTMGSFYLTVYGEGYEVEHNFVVADANLVVDLTPPVTSLP-------------------------------------------SNREETIEITGRVGSVKGKFSDRLLKLQDLIPLIAAVGEDDKSDPKKE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSKQFKMNTVLLVDKSELQLVMDQTKLMSRTVGGRVSLLWENLKDST--------------SQAGSLVIFSQKSEVWLKHTSVILGEAQLRDFSVLATTEAWSHKPTILIN------------NQCADLHFRAMSSTEQLVTAITEIR---------------------------ESLMMIKERIKFKPKSKKKSQFVDQKINTVLSCYFSNVSSEVMP------LSPFYIRHEAKQLDIY---------------------------------FNKFGSNEILLSIWDTDFFMTSHQTKEQYLRFSFGDIEIKGGISREGYSLINVDIS-------------------------------------------------------------ISMIKLTFSEPRRIVNSFLQ------DEKLASQGINLLYSLKPLFFSSNLPKKEKQAPSIMINWTLDTSITYFGVLVPVAS----------------------------------------------------------------TYFVFELHMLLLSLTN-----------------TNNGMLPEETKVTGQFSIENILFLIKE---------------------------------------------------------------------------------------------------RSLPIG------------------LSKLLDFSIKVSTLQRTVDTEQSFQVESSHFRVCLS----------PDSLLRLMWGAHKLLDLSHYYSRR-----------HAPNIWNTKMFTGKSDKSKEMPINFRSIHILSYKFCIGWIFQYGAGSNPGLMLGYNRLFSAYEKD------------------------------------------------FGKFTVVDAFFSVANGNTSSTFFSE--------GNEKDKYNRSFLPNMQISYWFKRCGELKDWFFRFHG---------------------------------------------------------EALDVNFVPSFMDVIESTLQSMRAFQELKKN---------------------------------------------------------------------------------------------------------------------------------------ILDVSESLRAENDNSYASTSVESASSSLAPFLDNIRSVNSNFKYDG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVFRVYTYEDIETKSEPSFEIKSPVVTINCTYKHDED-----------------------------------------------------------------KVKPHKFRTLITVDPTHNTLYAG------------------------------------------------------------------------------CAPLLMEFSESLQKMIKKHSTDEKPNFTKPSSQ--------------------NVDYKRLLDQFDVAVKLTSAKQQLSLSCEPKAKVQADVGFESFLFSMATNEFD---------------------------------------------------------------------------------------------------------------SEQPLEFSLTLEHTKASIKHIFSREVSTSFEVGFMDLTLLFTHPDVISMYGTGLVSDLSVFFNVKQLQNLYLFLDIWR--------------------------------------------------------------------------------------------FSSILHTRPVQRTVNKEIEMSSLTSTNYADAGTEIPWCFTLIFTNVSGDVDLGPSLGMISLRTQRTWLATDHYNEKRQLLHAFTDG-------ISLTSEGRLSGLFEVANASWLSEVKWPPEKSKNTHPLVSTSLNIDDIAVKAAFDYHMFLIGTISNIHFHLHNEKDAKGVLPD-------------LLQVSFSSDEIILSSTALVVANILDIYNTIVRMRQDNKISYMETLRDSNPGESRQPILYKDILRS-------------------------------LKLLRTDLSVNISSSKVQISPISLFDVEVLVIRIDKVSIRSETHSGKKLKTDLQLQVLDVSAALSTSKE----------------ELDEEVGAS--------------------------------IAIDDYMHYASKIVG------------------------------------------GTIIDIPKLAVHMTTLQ---------------EEKTNNLEYLFACSFSDKISVRWNLGPVDFIKEMWTTHVK----ALAVRRSQVANISFGQTEEELEESIKK----EEAASKFNYIA------------------------------------------------------------------------------------------LEEPQIEVPQIRDLGDATPPMEWFGVN-----------RKKFPKFTHQTAVIPVQKLVYLAEKQYVKILDDTH-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . :*. : : : :* .* . ::: : : : ::: :. .. *.*:: .::. * * :: :* : :::* * : : :: : :. *:.:***: * : : :. : * : . :: . . *.: . .* ...:: * :... . .: . .. : ::: . :: . . :*: *. : : * . *:: : :* *:: ::: ::: * : :*.: *. :: . : .. : :. * . :. ..: :: . . *:: : : : :. *.: .. * * .: . :* : : . . ::: :* . . : *: .: * : :: : : : : . : :: . . . **:: :: * :.. *.: :. :*. : :. :* : . . : .. * * : .. . * ::. : :::: . : : :. : :: . ::.. :. :* .* . * : :: .:: * :: : . . : . . : : : :. : * . . . ::. . . :. : : : . : :* :: *. . . : : : . : :.: ::. . . ..:. *: . . : .::. . * . . :: . : . :: . :: . * . . . * : :. : : .. : . .. : . * : : :: :* * . : :. : :. : . : . :: .. . : :.: * . :. . . : :. :. ::* : :* .: : : * . *: : . . : . .: . . .. . *. . . . . * : :. :.: . * :..: . : : . . .: .. :::. .:. : : : : *: .. . :: :: : * : . : : . * . . . * : . . .. .: . . * . :: : * . . :: : : : . : : : . :: . .: .::* * . . . *. . :.. : . : *: * . : . .. . : . .::. * :. : : *::* : . :: : : *... :. . : . :: ::. :::* ...:.: : .: : .: : . :* : . : :..:* .. : : . . . :*::: :* .:: . *: .::.. ::. . : * * :.:*: : ::: :* : *. :.:.*:. :.: ** . :*: .: ::*: : : :.* : :: :.: :. ::: . : : . . . *.*: :. : :. * ::** * :.:. .. : . . .. : . * : *.::. :** .:*::: .: . :.: ::: : :. :: *. : :* .:* : . : . :: * . . :*: : : . :.* .:: . * .** * . : : . :* :::* *. : * . . .** * . . : :** * ::*:. : : *: : ::::. . : : .:*:.:*..* :.: : . :* : :.. *. :::::* :: * * : . * . :. .. . : : :. . . .*. .:.: .: : .* :.. .: * : : :. : . .*:. : .: . .* . :.: : : .*: :*. :::* . . ::: .: * : : : ...:::.: .: .: :: : ..: * . * . :. :. . : :: ::::: . . : *: : : . . : *. . * :* . ::.::::*. .*: :* : :.:.: : . . :: . .* *:* * : . *:::: ::::. .: : . .. .. . . : :. * :* :. : :: **: *..:**: :: : *::*: : : : : : ", "identical_positions": 174, "similar_positions": 929, "identity": "3.12%" }, { "cls_id": "homologset.agr.MGI:2444633", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GM81-1", "uniprot_id": "A0A8I6GM81_RAT", "id": "A0A8I6GM81-1", "name": "V-set and transmembrane domain-containing protein 4", "aln": "MMACGSDLPLRSGTVPSWQPSLLQMKTHNSASARVHHCASRGSPQFSHLRRGRGERGHRGLAEPVDEEAAPPARRRPRDPAALARTVVGGRGAGRARRAAALSRVTAPDGCGGKMRLRLLALAVAVLLG--LVPEICGALNVTVSPGPVVDYLEGENATLLCHVSQKRRKDSLLAVRWFFAPD-GSQEALMVKMTKLRVIQYYGNFSRIANQQRLRLLEERRGVLYKLSVLMLRPADQGQYVCKVQEISKLRNKWTAWSNGSSATEMRVISLKADEDSSFEKKKVTWAFFEDLYVYAVLVCCVGILSVLLFTLVIAWQSVFHKRKSRVRHYLVKCPQNSSGETVTSVTSLSPLQPQKGRRHKKK------ADVPPAVPAKAPIATTFHKPKLLKPQ-RKVTLPKITEENLTYAELELIKPHQ------------AAKGIPTSTVYAQILFEENKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "T1NXB5-1", "uniprot_id": "VSTM4_MOUSE", "id": "T1NXB5-1", "name": "V-set and transmembrane domain-containing protein 4", "aln": "------------------------------------------------------------------------------------------------------------------MRLRLLALAAAVLLG--PAPEVCGALNVTVSPGPVVDYLEGENATLLCHVSQKRRKDSLLAVRWFFAPD-GSQEALMVKMTKLRIIQYYGNFSRTANQQRLRLLEERRGVLYRLSVLTLRPTDQGQYVCKVQEISKHRNKWTAWSNGSSATEMRVISLKAGEDSSFEKKKVTWAFFEDLYVYAVLVCCVGILSVLLFTLVIAWQSVFHKRKSRVRHYLVKCPQNSSGETVTSVTSLAPLQPQKGKRQKKK------VDVPPAVPAKAPIATTFHKPKLLKPQ-RKVALPKITEENLTYAELELIKPHR------------AAKGVPTSTVYAQILFEENQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IW00-1", "uniprot_id": "VSTM4_HUMAN", "id": "Q8IW00-1", "name": "V-set and transmembrane domain-containing protein 4", "aln": "--------------------------------------------------------------------------------------------------------------------MRLLALAAAALLARAPAPEVCAALNVTVSPGPVVDYLEGENATLLCHVSQKRRKDSLLAVRWFFAHSFDSQEALMVKMTKLRVVQYYGNFSRSAKRRRLRLLEEQRGALYRLSVLTLQPSDQGHYVCRVQEISRHRNKWTAWSNGSSATEMRVISLKASEESSFEKTKETWAFFEDLYVYAVLVCCVGILSILLFMLVIVWQSVFNKRKSRVRHYLVKCPQNSSGETVTSVTSLAPLQPKKGKRQKEK------PDIPPAVPAKAPIAPTFHKPKLLKPQ-RKVTLPKIAEENLTYAELELIKPHR------------AAKGAPTSTVYAQILFEENKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NCH9-1", "uniprot_id": "A0A8M1NCH9_DANRE", "id": "A0A8M1NCH9-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------MKLSAVAIVLLTR-VFIGELSDALNVTVTPGPVSMCMEGDNITLSCLVSQKKRSSSVLVLRWLYFP-TPEDEHLVVRMG-MKKAKYYGNYSKLFPQTKFLLWEENDGQLYRLLIKNVSREDGGNYTCKVQEIRKHRNKWRASSNGTGSMELRVHHTPSTG-----KTDVIWRMFEDLYLCAVLICSIGLVCMLVFALTITCQHLQHKRRLRASYNLVKCPENSSGETVTSVSSCSPAMHRKEKRHKAQPRDVTEPPPPPQIPAKAPAPRKPRRTKLLKAQPTKT--SRVLEDSLTYAELELVKPKPVLKTDMTGCAQLEPKTHCTGTVYAQILFVEKQV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M9Q8Q6-1", "uniprot_id": "A0A8M9Q8Q6_DANRE", "id": "A0A8M9Q8Q6-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------MKISAVLTALLTN-LLLGNVCSSINVTVSPAPFTVVAEGQNITLSCQVSQRKRSASLPVVRWMFQPESGGEELLVARVN-MKRAKFYGNYTKSFRKPKMKLTVVKQGKIFNLLIVNISERDRGVYSCRVQEFNKHQERWKASTNSSASTQLRVHVLPAGR-----PKEDLWSLFEDVYLCAVLVCCVGLLCMCMFTIAVSCQYLQRKRRLKENYHLVKSPQNSSGETVTSLVSLSPALPKKVRKYKKN-KTVEQADVPPEIPAKAPIADKMRKPKLLKPQPRKVVLPKIAEESLTYAELELIKPLP------------EAKAAKTGTVYAQILFEDKPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: *: . * ::. ::****:*.*. **:* ** * ***::*. *: .:**:: :* *:.:: :: ::***::: : :: * . * ::.* : : * * * *:***: : :::* * :*.:.: ::** : .. * :***:*: ***:*.:*::.: :* :.: * : .**: : : ***.*:*********: * :* :* :: * : ** :***** . . ::.****.* *. .:: *:.********:** .* *.******** :: :", "identical_positions": 106, "similar_positions": 105, "identity": "23.3%" }, { "cls_id": "homologset.agr.MGI:2444637", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C120-1", "uniprot_id": "SH3R3_MOUSE", "id": "Q8C120-1", "name": "E3 ubiquitin-protein ligase SH3RF3", "aln": "MLLGASWLCASKAAATAARGEGE-DRQGEQQR----GAQARTEEDMDESSLLDLLECSVCLERLDTTAKVLPCQHTFCRRCLESIVCSRHELRCPECRILVGCGVDELPANILLVRLLDGIRQRPRTGASPGSSPPARPGPG--TFSALAGGAGGATGSPPCSPVFLSAAAGSSTSS-LCDVATNRSVPVAKTLSQLPYAKALYSYEGKEPGDLKFNKGDIIILRRKVDENWYHGELQGMHGFLPASYIQCVRPLPQALPQGKALYDFEMKDRDQDKDCLTFTKDEVLTVIRRVDDNWAEGMLGDKIGIFPLLYVELNDSAKQLIEMDKLCPAATTAYNYDALLSSDPSTVASVAPGPTLSSSGAVSAFQRRVDSKKNAKKRHSFTALSVTHKSSQAASHRHSMEISAPVLISSSDPRAAARIGELAHLSCTVPTQD-SSSAGPVPTALPRAAAVAGEQGMSPKVQLPLNVYLALYAYKPQKNDELELRKGEMYRVLEKCQDGWFKGASLKTGVSGVFPGNYVTPVSRVPGGGAGLPWNNVLGGSPLAKGMATIMHPGGGSLSSPATAARSALPLTTLQDHMQHPATSLPTGSCLRHSAQPTASQAGDTTIPTATHASAQALDRPTATVSPLRTQTSPSRLPSTGLRPRSVASPQHGQQSPAQMCPRPAIPFTSAASAITPPNVSAANLSGEVGGTPISGLSTPSLINTGFKPDDKKNEKKEKKSGLLKLLAGASTKKKSRSPPSVSPTHDPQSAMDTSLQGAMGPEVSPLTVHGRAGSCPIESEMQGAIGLEPLHRKAGSLDLNFSLSPSRQATLSMASIRPEPKPLPRERYRVVVSYPPQSEAEIELKEGDIVFVHKKHEDGWFKGTLQRNGRTGLFPGSFVESF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R6D9-1", "uniprot_id": "M0R6D9_RAT", "id": "M0R6D9-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MLLGASWLCASKAAATAAPGEGD-DRQGEQQR----GDQARTEEDMDESSLLDLLECSVCLERLDTTAKVLPCQHTFCRRCLESIVCSRHELRCPECRILVGCGVDELPANILLVRLLDGIRQRPRTGASPGSSPPARPGPG--TFPALAGGAGGATGSPPRSPVFLSAAAGSSTSSSLCDAATNRSVPVAKNLSQLPYAKALYSYEGKEPGDLKFNKGDIIILRRKVDENWYHGELQGTHGFLPASYIQCMRPLPQTLPQGKALYDFEMKDRDQDKDCLTFTKDEVLTVIRRVDDNWAEGMLGDKIGIFPLLYVELNDSAKQLIEMDKLCPAATTAYNYDALLSSDPSTVANVAPGPTLSSSGAVSAFQRRVDSKKNAKKRHSFTALSVTHKSSQASSHRHSMEISAPVLISSSDPRAAARIGELAHLSCAVPTQD-SSSAGPVPTAIPRAAAVAGEQGMSPKVQLPLNMYLALYAYKPQKNDELELRKGEMYRVLEKCQDGWFKGASLKTGISGVFPGNYVTPVSRVPGG-AGSPWNNVLGGSPLAKGMATIMHPGGGSLSSPATATRSALPLTTLQDHMQHPATSLPTGSCLRHTAQPAASQAGGTTIPTATHPSAQALDRPTATVSPLRTQTSPSRLPSTSLRPRSVVSPQHSQQPPTQMCPRPAIPFTSAASAITPPNVSAANLSGEVGGTPTSGLSTPSPINAGYKPDDKKNEKKEKKSGLLKLLAGASTKKKARSPPSVSPTHDPQSAMDSSLQGAVGPEVSPLTIHGRAGSCPVESEMQGAIGLEPLHRKAGSLDLNFSLSPSRQATLSTASIRPEPKPLPRERYRVVVSYPPQSEAEIELKEGDIVFVHRKHEDGWFKGTLQRNGRTGLFPGSFVESF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TEJ3-1", "uniprot_id": "SH3R3_HUMAN", "id": "Q8TEJ3-1", "name": "E3 ubiquitin-protein ligase SH3RF3", "aln": "MLLGASWLCASKAAAAAAQSEGDEDRPGERRRRRAAATAAGAGEDMDESSLLDLLECSVCLERLDTTAKVLPCQHTFCRRCLESIVCSRHELRCPECRILVGCGVDELPANILLVRLLDGIRQRPRAGTSPGGSPPARPIPGQSAAPTLAGGGGGAAGSTPGSPVFLSAAAGSTAGS-LRELATSRTAPAAKNPCLLPYGKALYSYEGKEPGDLKFNKGDIIVLRRKVDEQWYHGELHGTQGFLPASYIQCIQPLPHAPPQGKALYDFEMKDKDQDKDCLTFTKDEILTVLRRVDENWAEGMLGDKIGIFPLLYVELNDSAKQLIEMDKPCPAAASSCN--ASLPSDSGAVASVAPSPTLSSSGAVSAFQRRVDGKKNTKKRHSFTALSVTHRSSQAASHRHSMEISAPVLISSSDPRAAARIGDLAHLSCAAPTQDVSSSAGSTPTAVPRAASVSGEQGTPPKVQLPLNVYLALYAYKPQKSDELELHKGEMYRVLEKCQDGWFKGASLRTGVSGVFPGNYVTPVSRVPAGGAGPPRNNVVGGSPLAKGITTTMHPGSGSLSSLATATRPALPITTPQAHAQHPTASPPTGSCLRHSAQPTASQAR-STISTAAHSAAQAQDRPTATVSPLRTQNSPSRLPATSLRPHSVVSPQHSHQPPVQMCPRPAIPLTSAASAITPPNVSAANLNGEAGGGPIGVLSTSSPTNTGCKLDEKKSEKKEKKSGLLKLLAGASTKKKSRSPPSVSPTHDPQVAVDALLQGAVGPEVSSLSIHGRAGSCPIESEMQGAMGMEPLHRKAGSLDLNFT-SPSRQAPLSMAAIRPEPKLLPRERYRVVVSYPPQSEAEIELKEGDIVFVHKKREDGWYKGTLQRNGRTGLFPGSFVESF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************:** .**: ** **::* . * : ***********************************************************************************:*:***.****** ** : .:****.***:**.* ***********::.* * : **.*:.*.**. . ***.**********************:*******:******:* :**********::***:: *************:*************:***:****:********************************* ****::: * * *.**..:**.***.*****************.***:*************:****:**************************:******:.**** *****..***:****:*:**** .********:***********.*****:*********************:**:****************.* ** * ***:********::* ****.***** ***:*.***:** * * ***::* ********:***:**** :**.**:*.:*** *************.******:*.***:**.****.:*.*.*********:*****************.**.** * . ***.* *:* * *:**.*********************:************* *:*: ****:*****.*::********:*******:*:**************: ******.** *:****** *******************************:*:****:*********************", "identical_positions": 717, "similar_positions": 116, "identity": "80.83%" }, { "cls_id": "homologset.agr.MGI:2444639", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIK8-1", "uniprot_id": "D3ZIK8_RAT", "id": "D3ZIK8-1", "name": "", "aln": "-MGPRKKSVKVCVMDSEVPEEMTADEEKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKLKEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDCSFLTLLKKMPDVEQLYGLHPRYLERRRVRGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPENKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVLGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFVELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDNDNNAQNNNANIHDNNHHHPDDSDDDNDFRQDLQQG-EAQFAADALNEMEDMVQDDGEVVAESGSGVPAH-QGVLP-VDADEEQAGPSGLQRVVKPTPIAVHDSESDDEEDSLELQEVWIPKNGARRYSEREEKTGDSGQPRETAAVSGKGKTPLRKRYNNSHQMGQAKQFPLEESSCEKGCQVTSEQIKADMKAARDISEKKKTKDVYPSCS----TTAASTVGNSSSPSTASQSPDFVRTVTSGGSSEPSPPEVDVSRQCVCSPGGSEDSEAMEE-GDAESSVCPRCCCLRPQESQRRTSRRSDEERPSTSRACVVNGADGTRSAFSFRTLPQGGSSGPAHDERTNGSGCGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVPLIPESEIAKTKPCHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICVIHEFSNPPNVRNKVRIRNWMDTIANINQELIKYEFFLEATRTEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKRGVFQRVVAIFIHYCDVNGEPVEDDYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMI0-1", "uniprot_id": "FBX38_MOUSE", "id": "Q8BMI0-1", "name": "F-box only protein 38", "aln": "-MGPRKKSAKVCVMDSEVAEEMTADEEKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKLKEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDSSFLTLLKKMPDVEQLYGLHPRYLERRRVRGQEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPENKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVLGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWMRLVDINLVRCHALKLDSFGQFVELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDNDNNAPNNNANLHDNNHHHPDDSDDDNDFRPDLQAG-EAQFAADALNEMEDMVQEDGELVAESGNGMPAHNREVLP-VDADEEQAGPSGLQRVVKPTPIADHDSESDDEEDSLELQEVWAPKNGTRRYSEREEKTGDSGQSRET-AVSGKGKTPLRKRCNNSHQTGQAKPFPLEESSCEKGCQVTSEQIKADMKAARDVSEKKKSKDVYPSCSSSSSSTAASTAGNASSPSTASQSPDFARTVTSSGSSEPSPPEVDVSRQCVCSPGGSEDSEAMEE-GDAESSVCPRCCCLRPQESQRRTGRCSDEERPSTSRACVVNGADGTRSAFSFRTLPQGGSSGPAHDERTNGSGCGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVPLISESEVAKTKPCHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRNWMDTIANINQELIKYEFFLEATRTEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRTAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKRGIFQRVVAIFIHYCDVNGEPVEDDYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PIJ6-1", "uniprot_id": "FBX38_HUMAN", "id": "Q6PIJ6-1", "name": "F-box only protein 38", "aln": "-MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKLKEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRVRGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPENKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVLGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNND-DNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPG-EQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIP-VDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSREL-SVSGKGKTPLRKRYN-SHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCS----STTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEE-GDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F2P7-1", "uniprot_id": "E7F2P7_DANRE", "id": "E7F2P7-1", "name": "", "aln": "MMSPRRKVTRTHSLGGGTLSSLGHEEPKDYINELSHEVLCHIFRYLPMQDIMCMECLSRKLREAVTLYLRVVKVVDLCASRWWEYMPSGFTDSSFLMLMKKMPDLEQLYGLHPRYLERRRVRGYEAFSIPGVLEALQACPNLIGVETSHLELVEAVWNYMPQVHILGKFRNRNGAFPIPSENKLTIPAAAKIQTLHLVGVNVPEIPCLSMLRHLYLKWVRLTKPQPFKDFLCVNLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEQLELVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVFGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQCNMSHAELVKYGLADVIENPGIITDIGMKAVNEVFTSIKYLVIYNCPHLHNPHNWITDHSRWSRLVDLTLVRCHAIKLESFSQFIELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDNDNNNNNNHQNNNDANIPPNNNDNQVENVPQQNHRGPEAEIPVVEGMVAENIEPEPVLVAANPQEENQSSSQTPNPSLEQDEEQAGPSGVQTSVKKPSVVVSDSDSEDE-----YSPVRTP--AAARSQGQYPETEAQGKSSTAGTPHGKGKTPLRRRGP-----------QPQELSCEKGCQVTSEQIKADMKAATETAER-----------------GAKDRNSGSAPASN----------YSAGS-------------CVCSIRWREDSANQDDQGGAGDMVRTRCTCNRSRSSSENRTR-SGHGLPTGGDNHRAEEMEDRHSNASARTP----SSFEGHNNRTAGHSS------HRG----------PTDEFPRRPITRARSRLSSVPLVCESELPKAKPRTAVKRKRMADKSTSTSDPVTEDDHVQVLSLKSKNLVGITLTNCGITDLVLKECPKMMFVHATRCRVLKHLVVESAPIVNRFDYAQCKKLDMEQVLDQILRMPPERNRIIYMRPMQQIDSLALEKKLFSGPYPYHIAIIHEFSNPPNVRNKVRVRSWMDTIANISQELIKYEFFPEATRTEEDVKKYPSYPWGRDIYTLEGVVDGAPYSMITDFPWLRSLRTAEPNTYARYDFEDDESTTIYAPRRKGQLSADICMETIGEEISERRQTCKGVFQRVVVVFIHYCDVRGEPVEDDYI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.**:* .:. :.. ..: :* ***:*:**************:*************:**********:******.************.*** *:*****:****************** ******************:***********::*.***:*****************.****.** .******************:.******:****************:.********************************:**:******************************:****************************************************************..*::*:*********:******************:.****.**********:***:***** ****:.******:**:**.**:************************************************ *** **: * :* * ::.:: ::. : : * * ::.. *:: : :.*:. . : : * :: *********:* ** ..:. **:*:** . * * .: * . : :* . :. : ********:* :* ******************** : .*: *. ...*: : *.** *.** *** :: *.* . * .** * *.:.*... * *.. *: . .: :. :* * ** ** .*::** * .. :** ..:::****:******** * *: ***:.*:** *:**** *********** ******** ********:*:***********:******:*********** **.***************:*:******************:*****:*:*:**:***********.:***************:*.********.********* ****:***:****.*****:****************:*********:****::*********.:************************** ** :*:*****.:*******.*********", "identical_positions": 803, "similar_positions": 181, "identity": "66.97%" }, { "cls_id": "homologset.agr.MGI:2444646", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIH9-1", "uniprot_id": "HPDL_RAT", "id": "Q5XIH9-1", "name": "4-hydroxyphenylpyruvate dioxygenase-like protein", "aln": "MAAPARRLCHIAFHVPAGQPLARDLQRIFGFQPLAVREAGGWRQLALRSGDAVFLVNEGTGPREPLYGLDPHHSVPSATNLCFDVEDVDRAARALAARGCIMPVPPTRVRDAQGTATYTVVSSPAGNLSLTLLQRAGYRGSFLPGFRPLPCTPGPGWVSHVDHLTLACTSGSSPTLMRWFHNCLGFHHLPLSPGEDPELGLKVAVGSGRGGLRLTALQTLPNSTVPTLVLAESLPGLTSEQDQVEQFLTRHGGPGLQHVGLYTPNIIDASEGMAKAGGRLLTPPEAYYQQPGKEEQILASGHKPSFLERQGILLDGDKDEFLLQVFTKSLFDEDTFFLELIERQGATGFGQNNIRALWQSVQEEAARAQGT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K248-1", "uniprot_id": "HPDL_MOUSE", "id": "Q8K248-1", "name": "4-hydroxyphenylpyruvate dioxygenase-like protein", "aln": "MTAPARRLCHIAFHVPAGQPLARDLHRVFGFQPLAVREAGGWRQLALRSGDAVFLVNEGTGPQEPLYSLDPHHSVPSATNLCFDVEDVDGAARALAARGCIMPVPPTRVRDAQGTATYTVLSSPAGNLSLTLLQRAGYRGSFLPGFRPLPCTPGPGWVSHVDHLTLACTSGSSPMLMRWFHDCLGFHHLPLSPGEDPEMGLKVAAGSGRGGLRLTALQTPPNNTVPTLVLAESLPGLNSKQDQVEQFLTRHGGPGLQHVGLYTPNIIDASEGMAKAGCRLLTPPEAYYQQPGKEEQILAAGHKPGLLERQGILLDGDKDEFLLQVFTKSLFAEDTFFLELIQRQGATGFGQNNIRALWQSVQEEAARAQGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96IR7-1", "uniprot_id": "HPDL_HUMAN", "id": "Q96IR7-1", "name": "4-hydroxyphenylpyruvate dioxygenase-like protein", "aln": "MAAPALRLCHIAFHVPAGQPLARNLQRLFGFQPLASREVDGWRQLALRSGDAVFLVNEGAGSGEPLYGLDPRHAVPSATNLCFDVADAGAATRELAALGCSVPVPPVRVRDAQGAATYAVVSSPAGILSLTLLERAGYRGPFLPGFRPVSSAPGPGWVSRVDHLTLACTPGSSPTLLRWFHDCLGFCHLPLSPGEDPELGLEMTAGFGLGGLRLTALQAQPGSIVPTLVLAESLPGATTRQDQVEQFLARHKGPGLQHVGLYTPNIVEATEGVATAGGQFLAPPGAYYQQPGKERQIRAAGHEPHLLARQGILLDGDKGKFLLQVFTKSLFTEDTFFLELIQRQGATGFGQGNIRALWQSVQEQSARSQEA", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*** *****************:*:*:******* **..*******************:*. ****.***:*:*********** *.. *:* *** ** :****.*******:***:*:***** ******:******.*******:..:*******:*********.**** *:****:**** ***********:**:::.* * *********: *.. ************ .:.********:** **************::*:**:*.** ::*:** *********.** *:**:* :* **********.:*********** *********:*********.***********::**:* :", "identical_positions": 286, "similar_positions": 61, "identity": "77.09%" }, { "cls_id": "homologset.agr.MGI:2444651", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2G1-1", "uniprot_id": "D4A2G1_RAT", "id": "D4A2G1-1", "name": "", "aln": "MGQTPALERCSAQLDAFPQLLRPQGMDAATAPKQAWLLWSPLLFLLLLPGGSISSCPTLCDCTSQTRAVLCAHRRLDTVPGGLPLDTEVLDLSGNRLWGLQRGMLSRLGQLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIVGPGIFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQQLEVGDNHLVFVAPGAFSGLAKLSTITLERCNLSTVPGLALAQLPALVALRLRELDIERLPSGALRGLGQLKELEIHHWPSLEALDPGSLVGLNLSSLAITHCNLSSVPFQALHHLSFLQVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLRLRRRLDFGTSPPACAGPQHVQGKNLREFSDILPPGHFTCKPALIRKSGPRWVIAEEGGHAVFSCSGDGDPAPTVSWMRPQGSWLGRVGRVRVLEDGTLEIRSVQLRDRGAYVCVVSNVAGNDSLRTWLEVIQVEPPNGTLSDPNVTMPGIPGPFSLDSRGVAMVLAVGFLPFLTSVTLCFGLIALWSKGKGRVKHHMTFDFVAPRPSGDKNSGGNRVTAKLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q149C3-1", "uniprot_id": "LIGO4_MOUSE", "id": "Q149C3-1", "name": "Leucine-rich repeat and immunoglobulin-like domain containing-NOGO receptor-interacting protein 4", "aln": "-------------------------MDAATAPKQAWLPWSPLLFLLLLPGGSISSCPTVCDCTSQTRAVFCAHRRLDTIPGGLPLDTELLDLSGNRLWGLQRGMLSRLGQLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIVGPGIFSGLTALTLLDLRLNQIVLFLDGAFSELGSLQQLEVGDNHLVFVAPGAFAGLAKLSTITLERCNLSTVPGLALAQLPALVALRLRELDIERLPAGALRGLGQLKELEIHHWPSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALHHLSFLRILDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLRLRRRLDFGTSPPACAGPQHVQGKSLREFSDILPPGHFTCKPALIRKSGPRWVIAEEGGHAVFSCSGDGDPAPTVSWMRPQGAWLGRVGRVRVLEDGTLEIRSVQLRDRGAYVCVVSNVAGNDSLRTWLEVIQVEPPNGTLSDPNITMPGIPGPFFLDSRGVAMVLAVGFLPFLTSVTLCFGLIALWSKGKGRVKHHMTFDFVAPRPSGDKNSGGNRVTAKLF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UY18-1", "uniprot_id": "LIGO4_HUMAN", "id": "Q6UY18-1", "name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4", "aln": "-------------------------MDAATAPKQAWPPWPPLLFLLLLPGGSGGSCPAVCDCTSQPQAVLCGHRQLEAVPGGLPLDTELLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEIHLWPSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLRLRRHLDFGMSPPACAGPHHVQGKSLKEFSDILPPGHFTCKPALIRKSGPRWVIAEEGGHAVFSCSGDGDPAPTVSWMRPHGAWLGRAGRVRVLEDGTLEIRSVQLRDRGAYVCVVSNVAGNDSLRTWLEVIQVEPPNGTLSDPNITVPGIPGPFFLDSRGVAMVLAVGFLPFLTSVTLCFGLIALWSKGKGRVKHHMTFDFVAPRPSGDKNSGGNRVTAKLF", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *********** *.************ .***::******.:**:*.**:*:::*********:************:******. *************************************:***:****:********************.******:****************:*******:****************:************** ***:*************** ***********************:***********:*****::**********************************************************************************************:**** ********:*****.*:*****************************************************:*:****.*********************************************************:*:******* *******************************************************************", "identical_positions": 548, "similar_positions": 37, "identity": "88.67%" }, { "cls_id": "homologset.agr.MGI:2444652", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQS7-1", "uniprot_id": "CC174_RAT", "id": "Q5PQS7-1", "name": "Coiled-coil domain-containing protein 174", "aln": "MDRKKKPLDVTASS--------LVDLKAELFRKQEEFKQEKLLKDSG-VFGKPKTSNKKPSIWSKQNAGVSSRAEKDAEQKLEEQKTLDKSREKLEEKAKLYEKMTKGDFLDEEVEDMYLVDFTQKIIDKRKEMEVLGATRDSRIKEERDAAVAAANDDDDEEEFSEKDIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPSLLEMDKNLQG-------------------------------RLFVSPANEKTLLSEDMR----KELQRQQWEEEEREALKKPMGPIHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRIKRENIKEKRKAILEARLAKLRQKKMKKSKVDGTEEESR-ADGVVTEPSEPKS--VPAPPPVAQSSKVEVIIQ--ERKDSKPGVPHIREWDRGKD--------------------------FSFGFWSKKQSELRAERDPEFAPPSNYFVGQKRTGSL-------------------SSQPWSRPGAAPSDLGHSSGQSQEPSSS---HTS-TPASE---------SSPQAPTVTFQTLDDMISYYKQVT-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U155-1", "uniprot_id": "CC174_MOUSE", "id": "Q3U155-1", "name": "Coiled-coil domain-containing protein 174", "aln": "MDRKKKPLDVTASS--------LVDLKAELFRKQEEFKQEKLLKDSG-VFGKPKTINKKPSIWSKQNAGVTSRAEKDAEQKLEEQKTLDKAREKLEEKAKLYEKMTKGDFLDEEVEDMYLVDFTQKIIVKRKEMEVLGATRESQIEEER--------DDDDKEEFSDKDIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPSLLEMDKNLQG-------------------------------RLFVSPANEKTLLSEDMR----KELQRQQWEEEEREALKKPMGPIHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRIKRENIKEKRKAMLEARLAKLRQKKMKKSKEDGTEEEGREADGVVPEPSEPKP--VPAPAPVAQNSKVEVIIQ--ERRDTKPGVPHIREWDRGKD--------------------------FSFGFWSKKQSELRAERDPEFAPPSNYFVGQKRTAPM-------------------SSQPQSRPGSAPSDLGHSSGQSQEPSSS---HTS-TPASE---------SSPQAPTVTFQTLDDMISYYKQVT-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PII3-1", "uniprot_id": "CC174_HUMAN", "id": "Q6PII3-1", "name": "Coiled-coil domain-containing protein 174", "aln": "MDRRKKPLDVTASS--------LVDLKAELFRKQEEFKQEKLLKDSG-VFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKAGER---------DDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQG-------------------------------RLFISPANEKTLLSEDMR----KELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKEGGTEEENRDGDVIGPLPPEPEA--VPTPRPAAQSSKVEVIVQ--ERKDTKPGVPHIREWDRGKE--------------------------FSFGYWSKRQSDLRAERDPEFAPPSDYFVGQKRTGFS-------------------SSQAWSRPGPAQSDPGQCPDQSHGPSPE---HTSPTPAPD---------NPPQAPTVTFKTLDDMISYYKQVT-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q641-1", "uniprot_id": "A0A8M9Q641_DANRE", "id": "A0A8M9Q641-1", "name": "", "aln": "MDKKKQPYSVTASSVSLFFISMLVDLKAELYRKQEQFKHDRLGQDAGGGAQKSKTKIKKPNIWSKQNEGVNARAQKDVQQTAEEENTLDKSRQKLEEKARLYEQMTKGDFPDEETESLFLVDFTQKIINQRNEPQTRTADRDG---------------EDSDVKVP---VPPPQNTNEEWVDYVDALGRSRRCLRKDLPDFQKMDEDLHN-------------------------------KRVTG--ADRHLLSEDMR----REMQREEWEREEEEQMKRPVGPIHYENIRDQEARELGVGYFAFAHDEDQRRKQRETLDMLRDQTTEQRSKREQLKEKRKALLEARLAKVRMRRMKNGKMEPGDEQVAPAADVAEIDEDDKDEDLVGPPAPAKVPKVEVEIQ--ERKDTKPGVPHVREWDRGKE--------------------------FSWGQWTSRR---REERDSEFAPPSAYFAEDRRANHSR------------------AGQSKGKHGFKWPESQNAAERHTEDNTSNPIYASEMPTYT---------QPSQTQTAQTQSLDDLLSYYKHST-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEB6-1", "uniprot_id": "Q9VEB6_DROME", "id": "Q9VEB6-1", "name": "CCDC174 alpha/beta GRSR domain-containing protein", "aln": "MNDPNKAISVNLSS--------LLSLKAELLRKQHEVRVAKATKASAADFRPTKSAGNKEKSSDQGYKKVASSDDGAKVYEAEDHAQLEKSRRILEAKSKFYDRMSRNGG-SLNSDDNCLVMFNRKKQEADREPEQCTQRRES----------------RQRLSSSSSSSQDEEGHDDLEVEYVDCLGRTRKCLRKDLKEAKRRDKQLAESMPERLDQTKANWMINTKGSRELNSNHNSDDESFIGPRPTESVFSEALSTMTKHDEQRMNWERKEQENFEKPD--VHYQDVFFDEARTHGVGYYAFSTDEDERRQQQLDLEKARQATKAKQMRRDELRAQRDRLVADRVLAAKNRIRERNGLPPISEEDYLREEQQKKDELAKEEAELNRAEQERRAAIERKKEKEEAELEELRKEHVRDWDKNKPGVRKLADSESAEPPEEEWKYKAERLPMSQEEWNEKQ---RAQRHAEFAPMPEPVPLKRSNFSSMPPPMVWNRAQEPQFHNFHSTKEEKKFQRRSYSANNEDEADEQPSTSSRGMGAAIPPPAGLDDRAPPAKKPKSQDDLERSIEAGLRFLRENCDKGVLGNKATWTAKADY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ::. .*. ** *:.***** ***.:.: : : :. .*: :* . .: * : *:. *:*:*. ** *:::*::*::.. . : :. ** *.:* .* : *:. . . . :. .: *:***.***:*:*:**** . . *::* . . . . ::** : :: ** :**.:*.* :::* :**::: :*** ****:**: *:: *.:* *: *: *. :: :*:::: :*. :: *: : : :.. .*: : : . :* : * . : *:*:**:.* :* *..:: * :*..**** . . .: : : : . : ... : *. . .:: :::: : : :. ", "identical_positions": 92, "similar_positions": 157, "identity": "15.38%" }, { "cls_id": "homologset.agr.MGI:2444654", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PDH4-1", "uniprot_id": "RNB3L_MOUSE", "id": "Q6PDH4-1", "name": "Ran-binding protein 3-like", "aln": "MSTTQRKDDSHLFTSSCTRQLQVQEDRQQQEKYVIAQPIFVFEKGEHNFKRPAEDSLEETAEPEFTGFLRKRVRSSSVTLHTTDPQSQG------------------------------VATLSQTRLRSSSFTDVPTFPPCRPVRKNNVFMTSRLLQRSDDMNNVEQGPPMRSSEQVLRPAVLQPSQ--TQSCQKAGTTFGPGALKSYKTKEKAEHEISEVGSSSSLLSENLPNARSSIQLSTDP-CISEAPSGCQPKEDKCSFTSCSSDFVFGENMVERVLGTQKLTQPPLQNLSYAKEKTFKSVLKFPN--AVSNSDSIENISLVESAAAFSSKPSQKCLLEKIDVITGEETEHNVLKINCKIFVFNKATESWSERGQGILRLNDTAGRECGTLQSRLIMRNQGSLRLVLNSRLWAQMKIQR------ASQKNLRITATDLEDDGIKIFLIQASAKDTGFLYAAIHHRLVALRSLAKQGDGGPAESQ--SDTALPQLNGESCDEDEDE-----------IAQVTKNGSDPSRWSHRQSIVCS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5YCF1-1", "uniprot_id": "A0A8I5YCF1_RAT", "id": "A0A8I5YCF1-1", "name": "Ran-binding protein 3-like", "aln": "MSTTPRKDDSHLFTSVRPCQLKVQEEQQPQEKYVIAQPIFVFEKGEHNFKRPAEDSLDEAAELEFTGFLRKRVRSSSVTLRTTDSQSLGDLNCSPNNRVPVELDKRPSSLMTCICNLLLVAALSQARLRSSSFTDVPTFPPSRPVRKNNVFMTSRLLQRNDDMNNVGQGPPVRPSDHVLRPAVLQPSR--TQSCQKGGTTLGPGASKTCETKENTEHKISEADS--SLLSENLSNARSSVQMSTDP-CISEAPSGGHPKEDECSFTSCSSDFVFGENMVERVLGTQKLTQHPLQNLSYAKEKSFKSLLKFPN--VASNSEPIKNISLIESAAAFSSKPSQKCLLEKIDVITGEETEHNVLKINCKIFVFNKATQSWSERGQGVLRLNDTAGSECGTLQSRLIMRNQGSLRLVLNSRLWAQMRTQR------ASHKSLRITATDLEDDRIKIFLIQASAKDIGFLYAAIHHRLVALRSLGQQGDGGPAGKQ--ADTVLPQVSGGSCDEDEDD-----------ITQVTKTGPDPSRWNHRQSIVCL------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q86VV4-1", "uniprot_id": "RNB3L_HUMAN", "id": "Q86VV4-1", "name": "Ran-binding protein 3-like", "aln": "MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEAAEPECNGFPTKRVRSSSFTFHITDSQSQG-------------------------------------------------------VRKNNVFMTSALVQSSVDIKSAEQGP-VKHSKHVIRPAILQLPQ--ARSCAKVRKTFGHKALESCKTKEKTNNKISEGNS--YLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQR------ANHKNVRITATDLEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQAESL--SETAQ-QLNCESCDENEDD-----------FIQVTKNGSDPSSWTHRQSVACS------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VCI7-1", "uniprot_id": "Q9VCI7_DROME", "id": "Q9VCI7-1", "name": "", "aln": "---MSENNEASVETNCFRGGFTLKASRLGG--AVLRPAVLANSSGSN--NSSTSPSAGEDSALLNNPFLRESKDDD-------DDEE--------------------------------------------------------VVATGSAAAESTGDKEDDDVDERPDPLTKLRSNGIERSSMFAAAKNNMPNVQSSGFVFGQNVHERVVAPN-----------------------AEQVTAEPDADTAASSVSAQEAASSSTAATSSSAPLLFSSVIQNAAQTTETSEAAASSSICSSS---------------SNNKESAEAKSLTDVAREYEESRAQKRKYEEVETFTGEEDEINIIDVSCKLFAFLNS--NWEERGRGSLRLNDAKDLRG---DSRVVFRTSGNLRLLLNTKVWAAMVAER------ASQKSLRLTAIDNSG-VVKIFLAMGRPADIAQLHKALSERIAKRKVSHPEECSVEEAKNGVASEAAASLQPESTTHDDEDEDAAPGPSGAISAEADSYGPSPKKVIVQPDSSADVPVPPVEEGDEDAEAEAKESTDQN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40517-1", "uniprot_id": "YRB2_YEAST", "id": "P40517-1", "name": "Ran-specific GTPase-activating protein 2", "aln": "---MSETNGGNAARENSEVKQTAVEN--------------PIDKLDGTPKRPREKDQDEQAEETSD------------------------------------------------------------------------------KSEAPNKNDEEKKEEGKKDQEPSHKKIKVDDGKTVESGIVEDDKKEDKFVFGAASKFGTGFGVAKKDTK-----------------------------DGDATTSTESLPASDSKTKKPFAFGSGLSFGSGFNILKNKTENNSESEKKATD--------------------VDKDKVHSGSEQLANASEDTKDKPKPLKLQKQEVKSGEESEECIYQVNAKLYQLSNIKEGWKERGVGIIKINKSK---DDVEKTRIVMRSRGILKVILNIQLVKGFTVQKGFTGSLQSEKFIRLLAVDDNGDPAQYAIKTGKKETTDELYNIIVKSVPK-----------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... . . . .. . : . . * : . : . . .. . . ...:. : :* : . : : . .. .. ... : . : : .:. . .. . . . * .. .: :: :. :*** * : .:..*:: : : .* *** * :::*.: .:*:::*. * *:::** :: : :: ..* :*: * * .. : : . *: : . : ", "identical_positions": 25, "similar_positions": 104, "identity": "4.39%" }, { "cls_id": "homologset.agr.MGI:2444661", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGE4-1", "uniprot_id": "SUSD6_MOUSE", "id": "Q8BGE4-1", "name": "Sushi domain-containing protein 6", "aln": "MCHGKIAPKSSSEFVVTSVGHGVFLQLVIL----------------------------------------------------CALLG------------DGLASVCPLPPEPENGGYICHPRPCKDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWTPAMEVSCHLIEDKETHA-LGVPALSIVASTASSVALILLLVVLFVLLQPKLKSFHHSR-REQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCMPPADPRVQIVLSEGSAPSGRNMPREQQLQGQEACSSAGGEDEAPGHSGLCEAWGSQGSETVMVHQATTSSWVAG-SGSSRPTHKDTADSENSDIQSLLSLTS-EEYTDDIPLLKEA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A096MK85-1", "uniprot_id": "A0A096MK85_RAT", "id": "A0A096MK85-1", "name": "", "aln": "MCHGRIAPKSSSEFVVTSVGHGVFLQLVIL----------------------------------------------------CSLLG------------DGLASVCPLPPEPENGGYICHPRPCKDPLTSGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEVSCHLNEDKETHASLGVPALSIVASTASSVALILLLVVLFVLLQPKLKSFHHSR-REQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCMPPADPRVQIVLSEGSAPSGRNMPREQQLQGQAACSSAGGEDEAPGHSGLCEAWGSQGSETVMVHQATTSSWVAG-SGSSRQTHKDTADSENSDIQSLLSLTS-EEYTDDIPLLKEA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q92537-1", "uniprot_id": "SUSD6_HUMAN", "id": "Q92537-1", "name": "Sushi domain-containing protein 6", "aln": "MCHGRIAPKSTSVFAVASVGHGVFLPLVIL----------------------------------------------------CTLLG------------DGLASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDTHTSLGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSR-RDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGPSGRSVPREQQLPDQGACSSAGGEDEAPGQSGLCEAWGSRASETVMVHQATTSSWVAG-SGNRQLAHKETADSENSDIQSLLSLTS-EEYTDDIPLLKEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "U3JAN2-1", "uniprot_id": "U3JAN2_DANRE", "id": "U3JAN2-1", "name": "", "aln": "MCNGMVACETRASLAHGVASTSLLLLLAMLPTGQASGCPRPTVVPHGRGNLTEMNRGSFSVGTLLQYSCDPGYTLDGVSMISCTVTGQWSSNPPRCIKNDGMYDVCQPPSEPENGGYNCHPSPCHR-LTQGTVIEYFCDEGYILKGGYQFRTCESGEWNSPMQISCHPVQGEEQHSSLPMPALSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRSREQGVSGQHSSMMVGGVQVSLPSYEEAVYGAGGTSVPPPESRVQIVLSEGPQAEALHEPLEQAQASYSFPSTSAAASSCHAETVLVHQVACSSS----PSSSSSPSWAVEQPGAAAPLHRQQS-SESSDQHSLLSVTSAEDYGDDIPLLKEA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* :* :: : :. .. .::* *.:* *:: * **: .** *.******* *** **: ** *:****:* ***:***.*:: **:.***...*::**: :.:: *: * :*:*********************************** *:*****:: *:**.****:**********:.* .:**.:.*********. ... * ** . *::.. ... ..: * . .. .* .:::.**.. .* *:: : **.** :****:** *:* *********", "identical_positions": 153, "similar_positions": 88, "identity": "41.35%" }, { "cls_id": "homologset.agr.MGI:2444662", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NUT2-1", "uniprot_id": "D19L2_HUMAN", "id": "Q6NUT2-1", "name": "Probable C-mannosyltransferase DPY19L2", "aln": "------MRKQGVSSKRLQSSGRSQSKGRRGAS---LAREPEVEEEMEKS------ALGGGKLPRGSWRSSPGRIQSLKERKGLELEVVAKTFLLGPFQFVRNSLAQLREKVQELQARRFSSRTTLGIAVFVAILHWLHLVTLFENDRHFSHLSSLEREMTFRTEMGLYYSYFKTIIEAPSFLEG-LWMIMNDRLTEYPLIINAIKRFHLYPEVIIASWYCTFMGIMNLFGLETKTCWNVTRIEPLNEVQSCEGLGDPACFYVGVIFILNGLM-MGLFFMYGAYLSGTQLGGLITVLCFFFNHGEATRVMWTPPLRESFSYPFLVLQMCILTLILRTSSNDR-RPFIALCLSNVAFMLPWQFAQFILFTQIASLFPMYVVGYIEPSKFQKIIYMNMISVTLSFILMFGNSMYLSSYYSSSLLMTWAIILKRNEIQKLGVSKLNFWLIQGSAWWCGTIILKFLTSKILGVSDHIRLSDLIAARILRYTDFDTLIYT----------CAPEFDFMEKATPLRYTKTLLLPVVMVITCFIFKKTVRDISYVLATN----------------------------------------------------------------------------IYLRKQLLEHSELAFHTLQLLVFTALAILIMRLKMFLTPHMCVMASLICSRQLFGWLFRRVRFEKVIFGILTVMSIQGYANLRNQWSIIGEFNNLPQEELLQWIKYSTTSDAVFAGAMPTMASIKLSTLHPIVNHPHYEDADLRARTKIVYSTYSRKSAKEVRDKLLELHVNYYVLEEAWCVVRTKPGCSMLEIWDVEDPSNAANPPLCSVLLEDARPYFTTVFQNSVYRVLKVN------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NXN4-1", "uniprot_id": "D19P1_HUMAN", "id": "Q6NXN4-1", "name": "Putative C-mannosyltransferase DPY19L2P1", "aln": "------MKKQGVNPKPLQSSRPSPSKRPYGAS---PAR----ELEVEKS------ALGGGKLPGGARRSSPGRIPNLKKRKGLELKVVAKT-LLDPFQFVRNSLAQLREEVHELQARWFPSRTTLSIAIFVAILHWLHLVTLFENDRHFSHLSSLEWEMTFRTKMGLYYSYFKTIIEAPSFLEG-LWMIMNDRLTEYPLVINTVKRFHLYPEVIIAAWYRTFIGIMNLFGLETKTCWNVTRIEPLNEFKAVKDW-----------EILLAFM-LV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M0RC58-1", "uniprot_id": "M0RC58_RAT", "id": "M0RC58-1", "name": "", "aln": "MVGQTRSKLRDASPDGPQSSRTGQARRRRSAGTVEPQQERSAPQERTKWSLLQHFLLGGRKLPSGARNYAARRIRNLNAQNYFPLEEVTKILLHDRFQFLHTLLDHFREKVQALQIHRFSHRTLFGVAAFVGILHWLHLITLFENDRHFSHLSSLEREMTFRTEMGLYYSYFKTIIEAPSFLEG-LWMIMNDRLTEYPLVINTVKRFHLYPEVIIAFWFRTVIGILNLFGIESKTCWNVTRMEPLNEVQSCEGLGDPACFYIGVIFILNGLM-MGLFFIYGTYLSGSQLGGLITVACYFFNHGEATRVMWTPPLRESFSYPFLVLQMYVLTTILRASTIHK-KHYIALCFSNVAFLLPWQFAQFILFTQIASLFPMYVVGYIEPSKFQKIIYINMGSVALCFILMFGNPMYLSSYYSSCLIVSWAILQKKNKIQKLVASELQFWLAQGCAWWCGTIILKFGTSKICGVSDHIRLSDLIAARILRYTDFDTLIYT----------CAPEFDFMERATPLRYTKTLLLPLVLVITYLIFKMIVRDILCVLYTN----------------------------------------------------------------------------TYQRKQLLDNGELIFHALQLLAFMGLAILIMRLKLFLTPHMCLMASLICSRRLFGWLFCRIHFENVVFGILTMMSIQGCANLHNQWSIMGEFTNLPQEELIHWIRHNTRPDAVFAGAMPTMASIKLSTLHPIVNHPHYEDADLRARTKIVYSAYSRKPAVEVRNKLLELHVNYYVLEEAWCVVRTKPGCSMLEIWDVEDPSNAANPPLCSILLKDSRPYFTTVFQNSMYRVLKIN------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0CW70-1", "uniprot_id": "D19L2_MOUSE", "id": "P0CW70-1", "name": "Probable C-mannosyltransferase DPY19L2", "aln": "MVGPTRSKLREGSSDRPQSSCTGQARRRWSAATMEPQQERSAPQERTKWSLLQHFLLGGRKLPSGARNYAARRIQSLNAQNYFQLEEVAKLLLLNRFQFLFTLLDHFREKVQALQMHRFSHRTLFGLAIFVGILHWLHLITLFENDHHFSHLSSLEREMTFRTEMGLYYSYFKTIIEAPSFLEG-LWMIMNDRLTEYPLVINTVKRFHLYPEVVIAYWYRTIIGIMNLFGIETKTCWNVTRMEPLNEVQSCEGLGDPACFYIGVIFILNGLM-MGLFFIYSTYLSGSQLGGLITVACYFFNHGEATRVMWTPPLRESFSYPFLVLQMYILTIILRTSTVHK-KHYMALCFSNVAFMLPWQFAQFILFTQIASLFPMYVVGYIEPSKFQKIIYVNMSSVALCFILMFGNSMYLSSYYSSCLLVTWAIMQKKSKIQKLGGTELQFWLIQGCFWWCGTIILKFLTSKICGVSDHIRLSDLIAARILRYTDFDTLIYT----------CAPEFDFMEQATPLRYIKTLLLPLILVITYLIFKKIVRDIMCVLYTN----------------------------------------------------------------------------TYVRKQLLDNAELIFHTLQLLAFTGLAILIMRLKLFLTPHMCIMASLICSQRLFGWLFCRIHFENVVFGILTMMSIQGCANLHNQWSIMGEFTNLPQEELIHWIKHSTRPDAVFAGAMPTMASIKLSTLRPIVNHPHYEDADLRARTKIVYSVYSRKSAVEVRNNLLKLHVNYYVLEEAWCVVRTKPGCSMLEIWDVEDPSNAANPPLCSILLKDSRPYFTTVFQNSMYRVLKIN------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZN68-1", "uniprot_id": "D19P2_HUMAN", "id": "Q6ZN68-1", "name": "Putative C-mannosyltransferase DPY19L2P2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAD-----------------SRRVIIASWYRTFMGIVNLFGLETKTCWNVTRIEPLNEVQSCEGLRDPACFYVGVIFILNGLM-MGLFFIYGTYLSGTELGGLITVLCFFFNHGEATCVMWTPPLRESFSYPFLVLQMYVLTLILRTSSNDR-RPFIALCLSNVAFMLPWQFAQFILFTQIASLFPMYVVGYIEPSKFQKIIYMNMISVTLSFILMFGNSMYLSSYYSSSLLMTWAIILKRNEIQKLGVSKLNCWLIQGSAWWCGTIILKFLTSKILGVSDHICLSDLIAAGILRYTDFDTLKYT----------CSPEFDFMEKATLLIYTKTLLLPVVMVITCFIFKKTVGDISRVLATN----------------------------------------------------------------------------VYLR---------------------------------------------------------------------------------------------CCLCRCHAYNGKCQAVYTSSHCESSTLRRCRLEAWLQHA---------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VWR8-1", "uniprot_id": "DPY19_DROME", "id": "Q9VWR8-1", "name": "C-mannosyltransferase dpy-19 homolog", "aln": "---MREPNLYVILSHALIGCGFFFLYVQHVRVIFETRTNIQQLNQLEREALLRREDALYYAFYKQLAEGPDFWHGYEQLKNVTDIEYPHSVNVLQRFYVLPELVTAYFFHVVRSGFNPMVQPMQF-YLEFVWLMGGVTLLVLYLYGTLLSEN--IFGGIYGVISYLMFHSFVAKIYERPLARENFAFPFIFLQMFYLCICIGRIIHRQRHTSRMFMIFAMSLFTACALLSWQFSTFIFTTQILIMMTSWNASALPTALVNAFVLDYSLSHLLGHALAFVMSHGNSQLLLTWQLSISLFLFLITMVRQLRHVRSRRLGHAQDLLNGDLFSLKFLMLTLLLASSVQTTLIELFNRAGVVSVTEGDQQHFFDICAHWALQVN--VGFVAHLSACNPQYARVAWSELWQLVKTMIVKPYCMYGVVMLAMFFRRWRKSGAPVSALTEEQRERARKYVLEDFIEEHFVSMSDMSSKETEKQLYKCFRLLKSCDYDYERYKRAQASLRKEQPPARDDFMQDIKRLRAQINRNSVKQRKERAQETKEAATDGASTPTEEEDKDPEAESESKKKNQEPGSGETETESAADPTETPPSRSADNEEEEEEHSATAAGCGSNSSGHRQRKRSSSRRSSVVPTANAQILNMHYVYSFLQMLVFTLIGLAVRKLFFLSFTQGCVIAPTVCSKLWYHRQRNIFWSVSLAVFLLSMFDPGMVNIREEYFPTRYSKSGDDLDSMLEWIKLNTERDAVFAGPVDIIGTVHLTTKRPIVNHAHLEMRQIAERTEHVYSVYSRQQSSDIYNQCAQLKIQYLIISLDECTNEVRDDCDLLAIWDDKQPAYQKYPQFCHELLHKNVPSFLKVFANDHYGIIKMFSQSVQINLKHNKMPEMSI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : :.: *:. : .* .*:: : . * :: ", "identical_positions": 4, "similar_positions": 18, "identity": "0.45%" }, { "cls_id": "homologset.agr.MGI:2444664", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A849-1", "uniprot_id": "D4A849_RAT", "id": "D4A849-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "---MWGRA--------------------------VRRRCPRGLRRGRE---ALLALLALAGLGAVLRAR--------------------------------------SRSGTVDPVPTRTPHPGRHEP------VLPRPPLPADALGAKGEAVRL--QLQGEELRLQEESVQRHQINIYLSDRISLHRRLPERWNPLCREVKYDYDNLPKTSVVIAFYNEAWSTLLRTVYSVLETSPDILLEEVILVDDYSDREHLKEPLANELSQLPKVRLIRASKREGLVRARLLGASAARGEVLTFLDCHCECHEGWLEPLLQRIHEKESAVVCPVIDVIDWNTFEYLG-NSGEPQIGGFDWRLVFTWHVVPQRERKLMRSPIDVIRSPTMAGGLFAVSKRYFEYLGSYDTGMEVWGGENLEFSFRIWQCGGTLETHPCSHVGHVFPKQAPYSR----SKALANSVRAAEVWMDDFKELYYHRNPQARLEPFGDVTERKKLRAKLQCKDFKWFLDTVYPELHVPEDRPGFFGMLENRGLRG-YCLDYNPPSENNVEGHQVLLYLCHGMGQNQFFEYTSRQEIRYNTRQPEACIAVEEGKDVLIMDLC---KDTVPENQEFVLQE-DGTLVHKQSGKCVEATEKEFDTSFAPHLRDCSSSDN-QRWLFKERMS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGT9-1", "uniprot_id": "GLT12_MOUSE", "id": "Q8BGT9-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 12", "aln": "---MWGRA--------------------------VRRRCPRGLRRGRE---ALLALLALAGLGALLRAR--------------------------------------SRSGTVDPGPPRTPLPGRHEP------VLPRPPLPADALGAHGEAVRL--QLQGEELRLQEESVKQHQINIYLSDRISLHRRLPERWNPLCREVKYDYDNLPKTSVVIAFYNEAWSTLLRTVYSVLETSPDILLEEVILVDDYSDREHLKERLANELSQLPKVRLIRASRREGLVRARLLGASAARGEVLTFLDCHCECHEGWLEPLLQRIHEKESAVVCPVIDVIDWNTFEYLG-NSGEPQIGGFDWRLVFTWHVVPQRERQSMRSPIDVIRSPTMAGGLFAVSKRYFDYLGSYDTGMEVWGGENLEFSFRIWQCGGTLETHPCSHVGHVFPKQAPYSR----SKALANSVRAAEVWMDEFKELYYHRNPQARLEPFGDVTERKKLRAKLQCKDFKWFLDTVYPELHVPEDRPGFFGMLQNRGLRG-YCLDYNPPNENHVEGHQVLLYLCHGMGQNQFFEYTTRKEIRYNTRQPEACITVEDGKDTLVMDLC---RETVPENQEFILQE-DGTLVHKHSRKCVEATEKVLDNGFAPYLRDCTNSDN-QRWFFKERMS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXK2-1", "uniprot_id": "GLT12_HUMAN", "id": "Q8IXK2-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 12", "aln": "---MWGRT--------------------------ARRRCPRELRRGREALLVLLALLALAGLGSVLRAQRG------------------------------------AGAGAAEPGPPRTPRPGRREP------VMPRPPVPANALGARGEAVRL--QLQGEELRLQEESVRLHQINIYLSDRISLHRRLPERWNPLCKEKKYDYDNLPRTSVIIAFYNEAWSTLLRTVYSVLETSPDILLEEVILVDDYSDREHLKERLANELSGLPKVRLIRANKREGLVRARLLGASAARGDVLTFLDCHCECHEGWLEPLLQRIHEEESAVVCPVIDVIDWNTFEYLG-NSGEPQIGGFDWRLVFTWHTVPERERIRMQSPVDVIRSPTMAGGLFAVSKKYFEYLGSYDTGMEVWGGENLEFSFRIWQCGGVLETHPCSHVGHVFPKQAPYSR----NKALANSVRAAEVWMDEFKELYYHRNPRARLEPFGDVTERKQLRDKLQCKDFKWFLETVYPELHVPEDRPGFFGMLQNKGLTD-YCFDYNPPDENQIVGHQVILYLCHGMGQNQFFEYTSQKEIRYNTHQPEGCIAVEAGMDTLIMHLC---EETAPENQKFILQE-DGSLFHEQSKKCVQAARKESSDSFVPLLRDCTNSDH-QKWFFKERML---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TDK4-1", "uniprot_id": "A0A8N7TDK4_DANRE", "id": "A0A8N7TDK4-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "-MAICGRR--------------------------SRSKFILYIVGAFVVGYLVFHRNTQSDVG-LAKIR------------------------------------------EVPDEHKNVDEQFLKRP------VYEKPALDVNALGEMGRAVKL--DLSGEEKREEEESIKKHQINTYVSDRISLHRRLAERWNPLCRNLKYDYLSLPTTSVVIAFYNEAWSTLLRTVHSVLETSPDLLLNEVILVDDYSDREHLKEPLENYIADLKKVRLIRARKREGLVRARLLGASIATGEVLTFLDCHCECHEGWLEPLLQRIKEEPSAVVCPVIDVIDWNTFQYLG-NPGEPQIGGFDWRLVFTWHSIPEHEQKRRSAATDVVRSPTMAGGLFAVNKKYFLYLGTYDTGMEVWGGENLEFSFRIWQCGGSLEIHPCSHVGHVFPKKAPYSR----NKALANSVRAAEVWMDDFKEVYYHRSPHARLEAYGDVTDRRKLRMRLRCKDFRWFLDNIYPDIQVPEDKPGMFGMLKNKGMTN-YCFDYNPPDEHKIAGHRVILYPCHGMGQNQFFEYSTLQEIRYNTRDPAGCVVADPVSTFLTMNLCSKPREAVPEDQKFLFRE-DGSLYHVQTQKCVEAVDRTDAGSPGPALRPCSDSDA-QKWFFEERT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MRC9-1", "uniprot_id": "GALT9_DROME", "id": "Q8MRC9-1", "name": "Putative polypeptide N-acetylgalactosaminyltransferase 9", "aln": "MAFIWRRRSTTIVKLVAFALAIWFCIAFLVYTDDTRRRAAQEGAGASGAGSAPGVGGGAGGLGDPIALALRNEPAGEDFGINGNVIGGGGQKQAHDEADIPPTVGKHKADLQAERMRKKAAEQPKKKPQEDSKKVIDPPANFEENPGELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAYPKVQIIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYRDSGGVNVGGFDWNLQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRSGVNVLKKNSVRLAEVWMDEYSQYYYHRIGNDKGD-WGDVSDRRKLRNDLKCKSFKWYLDNIYPELFIPGD-SVAHGEIRNLGYGGRTCLD--APAGKKHQKKAVGTYPCHRQGGNQYWMLSKAGEIRRDDS------CLDYAGKDVTLFGC----HGGKGNQFWTYRENTKQLHHGTSGKCLAISESKDK----LLMEECSASLSRQQWTLENYDSSKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * : . ..:* . .. :.* * *. : * *..*:* ::..* : ::. : :* *:** **:** *.: :. *:: .** *.*:*.*:****:.*****:***: **: *: ::******** ***. * : :: **::**. :****:***:***. * . ***:**.**** ********:** .: ::*********. :*::* :.* ::*****.* *:** :*::*: :. : : *********::.:.:* **:**:*:::*******:**: * *** ** *******:* *::**. . **** ******::.: **** . : : :***::*::** *:**.*:*:*:.:**:: :* * . .* :.* * . *:* .* :: : * * ** * **:: :. *** : : : : * . :* : :* * * : **: :. *: * *:* ::: ", "identical_positions": 209, "similar_positions": 155, "identity": "31.29%" }, { "cls_id": "homologset.agr.MGI:2444668", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q68FD7-1", "uniprot_id": "FNIP1_MOUSE", "id": "Q68FD7-1", "name": "Folliculin-interacting protein 1", "aln": "MAPTLFQKLFSKRSGLGAPGRDARDPDCAFSWPLPEFDPSQIRLIVYQDCERRGRNVLFDSSVKRK-NEDTSVSKLCNDAQVKVFGKCCQLKPGGDSSSSLDSSITLSSDGKDQCPKYQGSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQDSLEFINQDSNTLKAD-SSTVSNGLLGNIGLSQFCSPRRAFSEQGPLRLIRSASFFAVHSNPMDMPGRELNEDRDSGIARSASLSSLFITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENGVFPRWSVEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMKMSRRSADASQRSLAYNRILDALTEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNQLCHRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVGMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDLVQRLLYFLTYFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLITMHRNKSSLLFKESEETRTPNCNCKYCSHPVLGQNTENVSQPEREDTQDNSKELLGISDECQKISPPDCQEENAVDVQQYRDKLRTCLDTKLETVVCTGSAPADKCVLSETCLEPREESWQNKELLDSDNHTGTAMRPTGIVVEKKPPDKNVPSAFSCEVTQTKVTFLIGDSMSPDSDTELRSQAVVDQINRHHSEPLKEDRGVADKHQESK-ITKDQSEDSDTQNIVSGESCELPCWSHSDPE-SMSLFDEYFNDDS-IETRTIDDVPVKTSTDSKEYCCMLEYPKRLYTKTNKQKSELCKCIETVHQDSCNACFPQ-QDQRNSLSILVPHGDKESSDKKNAVGTEWDIPRNESSDSALGDSESEDTGPDIRRQAGGYCGGDQEDWTEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGNDERLRQCLVSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVLGIESSDLPLLAAVASTHSPYVAQILL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A2V5-1", "uniprot_id": "A0A8I6A2V5_RAT", "id": "A0A8I6A2V5-1", "name": "", "aln": "MAPTLFQKLFSKRSGLGASGRDARDPDCAFSWPLPEFDPSQIRLIVYQDCERRGRNVLFDSSVKRK-NEDTSVSKLCNDAQVKVFGKCCQLKPGGDSSSSLDSSITLSSDGKDQCPKYQGSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQDSLEFINQDSNTLKAD-SSTVINGLLGNIGLSQFCSPRRAFSEQGPLRLIRSASFFAVHSNPMDMPGRELSEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENGVFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMKMSRRSADAGQRSLAYNRIVDALTEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNQLCHRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVGMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDLVQRLLYFLTYFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEVEESEYVLITVHRNKSSLLFKESEETGTSNCNCKYCSHPLLGQNTENVSQLEREDIQDNSKELLGISDECQKIPPPDCQEENATDVQRYRDKLRARLDTKLETIVCTGSAPADKCVLSETGLEPTEESWQSKELLDSDNQTGTAMRPTGIVVEKKPPDKTVPSAFSCELTQTKVTFLIGDSMSPDSDTELRSQAVVDQINRHHSKPLKEDRGVTEKHQENK-ITKDQSGGSGTHNMVSGESCELPCWSHSDPE-SMSLFDEYFNDDS-IETRTIDDVPVKTSTDSKEYCCMLEYPKRLYTKDNKQQNELCKCIETVHQDSCNACFPQ-QDQRDALSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGPDIRRQVGSYCGGDQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERLRQCLASDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLAEYLRGQMRVHVKELGVVLGIESSDLPLLAAVASTHSPYVAQILL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TF40-1", "uniprot_id": "FNIP1_HUMAN", "id": "Q8TF40-1", "name": "Folliculin-interacting protein 1", "aln": "MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFDSSVKRR-NEDISVSKLGSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQDSLEFINQDNNTLKAD-NNTVINGLLGNIGLSQFCSPRRAFSEQGPLRLIRSASFFAVHSNPMDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENGVFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPE-SMSLFDEYFNDDS-IETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCFPQ-QDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVLGIESSDLPLLAAVASTHSPYVAQILL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IT71-1", "uniprot_id": "A0A0R4IT71_DANRE", "id": "A0A0R4IT71-1", "name": "", "aln": "MAPTLFHKLFNKKNPLSPPARCSRE-DTVFSWSSPELEPSQIRLIVYQDCERRGRNVLFDSDARKRSTEDGPATRVCGEAQVKMFGRCCQLRPTGGSSSSLDSSSSCASEPKEQNRFQASSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQMMLSKVFTARTGGSVCGSLNTLQDSLEFINQDSSTLRPEQNHTAANGFLGSIGFSQLCSPRRALSEQGPLRLIKSASFFSGHSNPMDMPGRGLYDERDSGIARSASLSSLLITPFPSPGSSLTSSCASSYQRRWLRSQTTSLENGVFPRWSVEESFNMSDESSGPSLGVARKKKIAIGVIFQLSPNEEENTKFQDFFFSHFPLFESHMNKLKSAIEQAMILSRRSADANQRALAYSRMVDGLNEFRTTICNLYTMPRVPEPVWLTMMSGPPEKNQLCGHFMRELALLMEQASKNQFLPALLTAVLTNHLAWVPTVMPNGQPPIQIFLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLSRTVVVGRRQELVQRLLYLLTYFIRCSELLETHLLESAEDEAIVMPGSLITTSLRRGEVEESEYVLVTMHK---------------------------------------------PSRDYLSQGDKSDPANPDEHQTEHTSDVPVCRVADSPLFDTRLETLVKVGSTSPSERRASVEVQEAQAEAGGVPIRIHHPSDS---------LLEKKPPDK----SFPDIEPSAKVTFLIGDSMSPESDLESRQQKVEQEIRRHKQKLLRD---AQQTNTENK-LQVDQIK-SKSREFVTG---RTPRWSASAQEDCVDMFEEYFSEDNPVQTLTIDDVYGKHAPKDK-------------------SDVQLECVR-VDAGCCKSCSSADLDKGIEISLSVPSAVEQ---KKAAPLNDWEIPRNESSDSALGDSESEDAGPDLPRADPD--GAFDSDFQDELELPLPGAKLVEN-YSKPSIANFGRSLFGGYCPSYVPDFVLQGVPNDEKLKQNLVSDLAHAVQHPVLDEPIAEAVCIIADTEKWTVTVASSQRRSSE-KLGKEVLVSSLVSGLLQSTLQLYRLNLSPNFCIMHLEDRLQELYFKSKMLAEYLRGQTRVHVKELGMVLGIESNDLPLLAAIASTHSPHVAQILL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:***.*:. *....* :*: * ***. **::***********************..::: .** ..::: .:****:**:****:* *.******** : :*: *:* .*************************************:***********.*:*****************..**:.: . *. **:**.**:**:******:*********:*****: ********** * ::**************:*******.**** ********** ****************:*****:****.**. *:.***********.** :*:**.**::************************ :*******.**:***.*::*.*.**************: **********.****:** :**:*:::***:**********:**********************:***********.****************************:******:**::******:********** ******..*********::***:*.:**:*******:*:*: *:: *. .*:.: * : * *:: ** * . :*::***:* .**.. .: * *. *: :. ..: ::******* :*. ..:************:** * *.* * ::* **: : *:: . : : *.* ** * ::::*: . * *. * * .:.:*:***.:*. ::* ***** * :...* .. :*:. * ..*::* . *: :*: ** . :: ** * .:*:******************:* *: * . *. :.*: :* *:*:**:**:* :*.********:****.**********: .**:::* * ***:********************* :**** ******* :: *************.**:******: *******:*****************:****** ********:******.*******:******:******", "identical_positions": 717, "similar_positions": 224, "identity": "61.23%" }, { "cls_id": "homologset.agr.MGI:2444671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA72-1", "uniprot_id": "D3ZA72_RAT", "id": "D3ZA72-1", "name": "", "aln": "MELRVANSNG---SCENGSIVSLYCSSQEVLCQIVRGIG------PEEPYNATLITWQERIR--KKYGFYIGVGLAFLSCFLIGTSVILKKKGLIRLVATGATRAVNGGYGYLKDPMWWAGFATMSAGEVANFGAYAFAPATVVTPLGALSVLISAVFSSYCLGESLNLLGKLGCVICMAGSTVMVIHAPKEEKITTVAEMASKMKDTGFIVFAVLLVVSCLILIFIVAPRYGQRNILIYIIICSVIGSFSVTAVKGLGVTIRN-FFQGLPVVHHPLPYILSLILGLSIIIQVNFLNRALDIFNTSLVFPIYYVFFTTVVVVSSIVLFKEWYTMSAVDIVGTLSGFVTIILGVFMLHAFKDLDISQISLPHTHKNTTPAPAPEPTVIKLEDKNVLVDNIELASTPSPQQKPKVFMIHS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZF2-1", "uniprot_id": "NIPA4_MOUSE", "id": "Q8BZF2-1", "name": "Magnesium transporter NIPA4", "aln": "MELRVANANG---SCENGSIVSLYCSSQEVLCQIVRGIS------PEEPYNATLITWQERVR--KKYGFYIGVGLAFLSCFLIGTSVILKKKGLIRLVATGATRAVNGGYGYLKDPMWWAGMATMSAGEVANFGAYAFAPATVVTPLGALSVLISAIFSSYCLGESLNLLGKLGCVICMAGSTVMVIHAPKEEKVTTVAEMASKMKDTGFIVFAVLLVVSCLILIFIVAPRYGQRNILIYIIICSVIGSFSVTAVKGLGVTIRN-FFQGLPVVRHPLPYILSLILGLSIIIQVNFLNRALDIFNTSLVFPIYYVFFTTVVVASSIVLFKEWYTMSAVDIVGTLSGFVTIILGVFMLHAFKDLDINQISLPHTHKNPTPAPAPEPTVIKLEDKNVLVDNIELASTPSPQQKPKVFMTDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0D2K0-1", "uniprot_id": "NIPA4_HUMAN", "id": "Q0D2K0-1", "name": "Magnesium transporter NIPA4", "aln": "MELRVSNT-----SCENGSLLHLYCSSQEVLCQIVNDLS------PEVPSNATFHSWQERIR--QNYGFYIGLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFLTMAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVIHAPEEEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFSVAAVKGLGITIKN-FFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVFMLHAFKDLDISCASLPHMHKNPPPSPAPEPTVIRLEDKNVLVDNIELASTSSPEEKPKVFIIHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QHP8-1", "uniprot_id": "F1QHP8_DANRE", "id": "F1QHP8-1", "name": "", "aln": "MGVTMKDIHLPSDSCINGSVIRIFCPTSASICVFDTAVGNTSYSLDNSNKNLTVSTQSLAIDKWSNYNFWTGLTLAVLSAFLIGGSVILKKKALLRLANTGETRAAEGGHGYLKDWLWWGGLLTMGGGEAANFAAYMFAPATVVTPLGALSVLISAVLSSHLFRETMNLLGKLGCMLSVLGSTLMVIHAPEEEEVTTLKEMAEKLLDPGFLVFASILLVTCLILIFYVSPRFGQSNILVYISICSLLGSFTVSSVKGLGIAIRT-MFTDTSVVRNPLMWILLLTLIGSIIIQVNYLNKSLDTFNTLLVYPIYYVFFTTVVLSTSVILFKEWGAMSGVDVVGTIGAFLVIVIGVSMLNIFKDLNVCFEDLRSNLCQPLSQESPS----KREDKHILIENIETLP-PMREEGPRVFIIS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PD12-1", "uniprot_id": "M9PD12_DROME", "id": "M9PD12-1", "name": "", "aln": "-------------MNSDGEASSLQMPQVTVGGMLPVEAN-------QSPETAPLS-MAETVS---NTDFYIGVGLAISSCFFIGSSFIIKKKALIRLSRYGEVRASAGGFGYLREWIWWAGLLTMGVGEAANFAAYAFAPASLVTPLGALSVIISAVMASRFLNEKLNLLGKIGCFLCILGSTIIVIHSPKEKEIEDLQLLFDMLLDPVFILYVICIVGSTVFVACFIAPRHGHTNVVVYIFLCSGIGSLTVMSCKALGLAIRQTLNNGGNVFLTWMPWFLILVTVTFIAIQMNYLNKALDIFNTSIVTPVYYVMFTTLVIAASAILFKEFTHMRFDDILGDVCGFLIVITAVFLLNAFRDIDISLNDVRGLMR-PKMQRVSQFDEEVLVTSNTKERRLSYGSSDIFRKAXHKQRYQV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. : . : . : . .. : : .*: *: **. *.*:** *.*:***.*:** * .** **.***:: :**.*: **. **.***.** ****::*********:***:::* : *.:*****:**.:.: ***::***:*:*::: : : . : *. *:::. :: : ::: ::**.*: *:::** :** :*:::* : *.**::*: : . *. : ::* * : *:*:**::** *** :* *:***:***:*: :* :****: * *: * : .*: :: .* :*: *:*::: .: . .. .: .:. . .: : ", "identical_positions": 120, "similar_positions": 131, "identity": "28.71%" }, { "cls_id": "homologset.agr.MGI:2444672", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WXG6-1", "uniprot_id": "MADD_HUMAN", "id": "Q8WXG6-1", "name": "MAP kinase-activating death domain protein", "aln": "--MVQKKKFCPRLLDYLVIVGARHPS---------SDSVAQTPELLRRYPLEDHTEFPLPPDVVFFCQPEGCLSVRQRRMS--LRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRISKE--------------------KGEGGAGSRGKEGTHATCASEEGGTESSESGS-------------------------------------SLQPLSADSTPDVNQ------SPRGK---------RRAKAGSRSRNSTLTSLCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK--SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQPALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN-AEVLPILPEPESLELKKHLKQALASMSLNTQPILN---LEKFHEGQEIPLLLGR----------------------------PSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAEKLARTQAVEYFGEWILNPTNYAFQRIHNNMFDPALIGDKPKWYAHQLQPIHYRVYDSNSQLAEALSVPPERDS-DSEPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDING---------DTPNVDPLTHAALGDASEVEIDELQNQK-EAEEPGPD-SENSQE---NPPLRSSSSTTASSSP--------------------STVIHGANS---EPADSTEMDDKAAVGVS-----------------------------------KPLPSV-PPSIGKSNVDRRQAEIGEG-----SVRRRIYDNPYFEPQYGFPPEEDED--EQGES-----YTPRFSQHVSGNR----------------------------------------AQKLLRPNSLRLASDSDAESDSRASSPNSTVSNT----STEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKVFGLNTLMEIVTEAGPGSGEGNRRALVDQKSSVIKHSPTVKREPPSPQG---RSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVLSKLNRMVQSEDDARQDIIPDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTESVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFIASIELWNKHQEVKKQKALEK-QRPEVIKPVFDLGETEEKKSQISADSGVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGPGGEGSVHLASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAG---SPIRTSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLISYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQINEVLDQLANLNGRDLSIWSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDLKTGEGGLLQVTLEGINLKFMHNQVFIELNHIKKCNTVRG-VFVLEEFVPEIKEVVSHKYKTPMAHEICYSVLCLFSYVAAVHSSEE------------------------------------DLR---TPPRPVSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80U28-1", "uniprot_id": "MADD_MOUSE", "id": "Q80U28-1", "name": "MAP kinase-activating death domain protein", "aln": "--MVQKK-FCPRLLDYLVIVGARHPS---------SDSVAQTPELLRRYPLEDHPEFPLPPDVVFFCQPEGCLSVRQRRMS--LRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRMPKE--------------------KVEGGAGPRGKEGAHTSGASEEAATGSSESGS-------------------------------------TLQPPSADSTPDINQ------SPWGK---------RRAKAGSRSRNSTLTSLCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKLGIPRGVQRDTMWRIFTGSLLVEEK--SSALLQDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQELQQALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN-AEVLPILPEPESLELKKHLKQALASMSLNTQPILN---LEKFHEGQEIPLLLGR----------------------------PSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAEKLARTQAVEYFGEWILNPSNYAFQRIHNNTFDPALIGDKPKWYAHQLQPIHYRVYDGNSQLAEALSVPPERDS-DSDPTEDSGSDSQDYDDSSSSYSSLGDFVSEMMKCDING---------DTPNVDPLTHAALGDASEVEIDELQPQK-EGEEPGPD-SENSQE---NPPLRSSSSTTASSSP--------------------STVVHSAHS---EAADSTEMGDKATAGIS-----------------------------------KPLPPV-PPSICKSTVDRRQTETGEG-----SVCQRTYDNPYFEPQYGFPPEEDEE--EQGES-----YTPRFSQHVSGSR----------------------------------------AQKLLRPNSLKLASDSDAESDSRASSPNSTVSNN----STEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKTTPFPSLKVFGLNTLMEIVTEAGPGSGEGNRRALVDQKSSVIKHSPTVKREPSSPQG---RSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVLSKLNRAVQSEDDARQDVIQDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTENVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATGKGPKELDTRSLKEENFVASVELWNKHQEVKKQKALEK-QRPEGIKPVFDLGETEEKKSQMSADSGVSLTSASQRTDQDSVIGVSPAVMIRSSSQDSEVSTVS-NSSGETLGADSDLSSNAGDGPGGEGSAHLASSRATLSDSEIETNSATSAIFGKAHSLKP--KEKPAG---SPIRSSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSLSKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLISYMLLMKVNKNDIRKKVRRLMGKSHIGLVYSQQVNEVLDQLNSLNGRDLSIRSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDMKTGEGGLLQVTLEGINLKFMHNQ-FLKLKKW--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08873-1", "uniprot_id": "MADD_RAT", "id": "O08873-1", "name": "MAP kinase-activating death domain protein", "aln": "--MVQKK-FCPRLLDYLVIVGARHPS---------SDSVAQTPELLRRYPLEDHPEFPLPPDVVFFCQPEGCLSVRQRRMS--LRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRMPKE--------------------KAEGGAGPRGKEGAHAPCASEEAATESSESGS-------------------------------------TLQPPSADSTPDVNQ------SPRGK---------RRAKAGNRSRNSTLTSLCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKPGIPRGVQRDTMWRIFTGSLLVEEK--SSALLHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQEVQQALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTN-AEVLPILPEPESLELKKHLKQALASMSLNTQPILN---LEKFHEGQETPLLLGR----------------------------FSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAEKLARTQAVEYFGEWILNPSNYAFQRIHNNTFDPALIGDKPKWYAHQLQPIHYRVYDSNSQLAEALSVPPERDS-ESDPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDING---------DTPNVDPLTHAALGDASEVEIDELQPQK-EGEEPGPD-SENSQE---NLPLRSSSSTTASSSP--------------------STIVHGAHS---EPADSTEVGDKAATGIS-----------------------------------KPLPPV-PPSICKSTVDRRQTETGEG-----SVCQRTYDHPYFEPQYGSPAEEDDD--EQGES-----YTPRFSQHASGSR----------------------------------------AQKLLRPNSLKLASDSDAESDSRASSPNSTVSNN----STEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKTTPFPSLK--------------------GNRRALVDQKSSVIKHSPTVKREPPSPQG---RSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVLSKLSRAVQSEDDARQDVIQDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTENVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATGRGPKELDTRSLKEENFVASVG-------------------PEVIKPVFDLGETEEKKSQISADSGVSLASASQRTDQDSVIGVSPAVMIRSSSQDSEVS----NSSGETLGADSDLSSNAGDGPGGEGSAHLASSRATLSDSEIETNSATSTIFGKAHSLKP--KEKPAS---SPVRSSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLISYMLLMKVNKNDIRKKVRRLMGKSHVGLVYSQQINEVLDQLTNLNGRDLSIRSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDMKTGEGGLLQVTLEGINLKFMHNQVFIELNHIKKCNTVRG-VFVLEEFVPEIKEVVSHKYKTPMAHEICYSVLCLFSYVAAVRSSEE------------------------------------DLR---TPPRPVSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58G4V6-1", "uniprot_id": "A0AC58G4V6_DANRE", "id": "A0AC58G4V6-1", "name": "MAP kinase-activating death domain protein", "aln": "---MEKKKMCPRLLDYLVVVGARQPS---------NDSVAQTPQLLRRYPLEDHNDFPLPPDVVFFCQPEGCLSIRQRRVS--LRDDTSFVFTLTDKDSGITRYGICLNFYRSFQKAHHRP--------------------RAEGKGEKPAHTDTAVEATEKSDPSTLTLSGE-------------------------------------HSAPPAGDGTLLPGEPGSSGKSPRSK---------RSGRIAPQNRNSMLTSLCILSHYPFFSTFRECLYILKRMVDCCSQRLN-QRPGAPKSTQRDTMWRVFTGALSVEEKEKGSQVLQDLREIESWVYRLLRSPVPVAGQRRVDVEVLPHELQPALTFALPDPSRFSIVDFPLHLPLELLGVDACLQVLACILLEHKVVLQSRDYNALSMSVMAFVSMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYVIGVPASFFLYKCDFKMPDDVWLVDLDCNKVIVPSN-AELLPPLPEPEASELKKHLKQALASMSLNTQPILN---LEKFQDGQELSLLP------------------------------PGRDKASPSSTEFNPLIYGNDVDSVDVATRVAMVRFFNSPNVLQGFQMHTRTLRLFPRPVVAFQSTSFLASRPRRNGFTEKLSHTQAVEYYGEWALNPTNLAFQRIHNNVYDPSLIGDKPKWYAHQLQPVFYRVYDGNSHLAEALSGPLQDETNDSDPTDDSGSDSEAYDDSSSSYSSLGDFVNEMIKGDIQG---------DTPNVDPLTHAALGDADEVEIHDFHEYKGDSGEPEPEGPTEAAD---SQPLRSSSSTTASSSP--------------------STVIQGVNH---EQKEPVEVEPIANVTFP-----------------------------------SSAPVLGPPPFTRPTPDPTLVDPAN--------KKREYDNPYFEPQYGFPTEEDAETDEQEES-----YTPRFNQNLNGNK----------------------------------------PSRPLRPSSLKLPGESDGEGDSRNSSPNSTISNN----SSDGFGGLMSFASNLYKNHGTSFSLSSLALPNK-AREKNTPFPSLK--------DDADDSPESPGARAPRALVDQKSSVIKHSPTVKRESPSPQG---RANNTSENQQFLKEVVQSVLEGQGVGWLNMKKVRRLLENEQLRVFVLSKLNRAVQSEEDAQQEVIRDVEINRKVYKGMLDILKCTVSSLEHSYTNAGLGGMASVFSLLEIARTHYQTKDPEKRKRSPTEGLSSPGSKESPSGRMESARAAGVLLVPRIQLPPPSS-GKSSRQFDTRSLNEENFIASIELWSKHQDNRKQKALEKEQRADGVKQRVEGGDTEEKKSQISADSGLSVTSGSQKSDTDSLASSEPPALTRSTSQDSEASTVVSNSSGETLGADSDLSSTAGDGLTGRHGQHLNLSRGTLSDSEIETNPATSSVFGKTHKLKPGVKEPVGVNKAAPAPPVEDVSMRIYLCEGLLGRDKSSVWDQLEDAAMETFSLSKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGDHDRKRLEDDEDRLLATLLHNMIAYMLMMKVGKNDIRKKVRRLMGKSHIGLTHSQEINEVLDRLAHLSGRELSIRPSGSRHIKKQTFVVHAGTDTTGDIFFMEVCDDCIVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRRNGQETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDMKTGEGGLLQVTLEGINLKFMHSQVFIELNHIKKCNTVKG-VFVLEEFVPETKEVVIHKYKTPMAHQICYSVLCLFSYMAAVKGKES------------------------------------EGKPKMLSPRPLAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXY2-1", "uniprot_id": "MADD_DROME", "id": "Q9VXY2-1", "name": "MAP kinase-activating death domain protein", "aln": "MSDQQKASLCPRLVDYMAIVGAHTTPPMPKGLQGLKAPPVQVPDLLRRYPPSDHADFPLPLDMVYFCQPEGCTSVGPRRTGSAIRDMTSFVFALTDKDSGKTRYGICVNFYRPIERPSSAAGSAGAGNDRPGNGGPGGHGGGAGGGAGGGGRGGRRSSAFRRESWRKSMERSSDSAFSSDYRSNVAPSDSDRELTSRRDSDQQRLHSHHSHHQPHHPSASPAVPKLGLMAPSADSESGGSHSPSPRASRKRTKLRNQSLTSLCIISHHPFFTTFRECLFILKKLIDACNESSSPKRVGASQKINRDNVWTVLTGHVSDATP---SIVLHDVREIETWILRLLSTPVPVPGSTRVEVEVLSPTVHEPLLFALPDHTRFSLVDFPLHLPLELLGVETCLKVWTLIMQENKVLFQSRDYNALSMSVMAFVTMLYPLEYMFPVIPLLPTCLSCAEQLLLAPTPFVIGVPASFLVYKKNFRLPDDIWVVDLDSTKLTPPTGGYEEIPPLPEPEGTILKNHLKQALTSMTATNTAVSSQQLLPSVRDSLQEPPLLGVSQVRLPLQTPPHSAQASQRNSMSAQGTISSRQPSPMNSPALNPFVYGTDVDSVDVATRVAMVRFFNAQNTLANFAEHTRTLRLYPRPVVAFQINSFLRSRPRASQFLNQFARTQAVEFLAEWSLTPTNVAFLRVQTGVMDPMQVGDKPKWFAHALTPIRFSVWDDGSSLNGALRSLKQLEC---QPTDESGSDSEGADSSSSSYSSLSDFVSEMASSDLSPSLHDVFGSYNRPHVVPQTLSSNLDPALVYHPPSKLQYPEGIADAVASKEEEDEERADSPVSSSSSRSDLSSPSFNRDSEFDFQPKGGQTLGSTTVGSGAAAPSFELATPLAMRLEATIKMASIEQESDTVSTATGKTIAAGSKLQRHPSDSESRPEKKIPPPLTPPVKQPGVSNILARTGSSGSSSSSPGRQSSQSSLFENFASHAKELVRETTRQSSQEGLLAHVDKFTLHAKKAAGEASKQALEVSKQAAGVSKNTLEDLTYVGKSTLGDLTKTAKEAATKKGIIKIEEHSAGGAGPPPKSPGSQLATHKQVQQSGGQGGGNNFFSAIGTDFNGLASSTSTMFSGMFGKKSQQKQVPVQQKQPNVSAGKAKSGINFDPFPGRKGLVERTPLIKHSGPRQTQEELTRQQNQERSHSNAENQTFLKDVTNQVLAGEGVGWLKLNRFKKLMEDESYRTLVLSKLNKTLD-KKIAPDDHIDDVCVTKPVWKGMLKCIQAIAGGLDVTFANFGLGGMASVFQLMEVAHTHYWSKEINEGSDMSSSLLSSHAAS--PMGSRENLRSPSSPNGSHSALGSEWASPQESRKSSTQLAHGG-------------------------------PGGSHSGAPINRRLSSADSQDGQSTTEMFKDMLSQKRSALKNMLTSFDSDTTTSKDSKKSSGNLWSGKSTLS--AGFRYTG---GHLINTSSSPSPD----------------------------------------SPRVYLFEGLLGKD---------------------RLNLWNQMQFWEDAFLDAVSQERDMIGMDQGPIEMMERYKSLSESERKRLEHDEDRLLSTMLYNLTAILVMLNVAKDEIRRKIRRLLGKSHIGLVYSQEVHNVVDQINNLNGNDIDLKPLGSRLLHRQSFTVHQGTDVNGPLRFMEVRDDGLVLRSVDGTIVERWWYERLVNMTYSPKTKLLCLWRRNGGQTQLHKYYTRKCKELYNCIKEAMERGGTPTN----VPELGGEFPVQDMNTGEGGLLQVCLEGVGLLFSNSKFFVRLDHIRKCFTQKGGIFVLEEYNPKTRNLIQRKYQSSMSDQICYSVLCVFSYVAAGQDQKKNPVVITPQIQDIHAQQKQKHQQQQQHQQPQQQQQPHQTTTQQNQPTAVASAVPTTTAPAGQVNPNRMTAKSQAGSISIRHTVPMQKPTITMSTVQPQARMPAQVATASVPVTVPVPPTPAPPTSNPAKLPQLPPRVPSQPSTESLASISSPPPKLRTPMSAPPGPPPAIPPRTGAISRSGSVPAARSFVRQASANSTPPQYTPQPPPPFVIPKRHSGLARASTLSSSTSPSMSSSSASNHPGHSQSQQRASHGSVAAVLQSMPEAEPGYGSGSGSISGSSSGSGSASGSIASASPQAHRKH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :****:**:.:***: .. . . .*.*:****** .** :**** *:*:******* *: ** . :** *****:*****:* ******:****.::: * . .: . .. .. * ..: : *. .: * .: : **. *****::**:***:******: **:::*.*.: :: * .: :**.:* ::** : * :*:*:****:*: *** :****.*. **::***. :: .* ***** :**::**************::**:* : *: *:**::****************:*:****************::.**********::*******::** :*::***:*:****..:: *:. * :* *****. **:******:**: .. .: . * ..::. : . * ..: . *. :**::**.******************: *.* .* *******:******** *** **** . * :::::*****: .** *.*:* ** *::.. ** :******:** * *: : *:*..* * ** : : :**::***** *.********.***.** . *:. : *:* * * :: *. * : :. : : . *: **** : *** :*: .. * . : * .. . * .*.. :. . . .. :: : . ** . . * : .* .. :. :*. : . . : . ::: .* . ... .**.* ::. .: * ** .* * : :.. * :. :. .::. .:: :.**::.. : : .* .:* : * *: ..:*** ***:*.:.** *:*****::::.::*:*.*. *.:*****.: :: :. * :: * ** :.: *:****. ::. . .*: :::: *******:* *:*:*:*** :*: :: . .:. :.: .. . . :: . .: . : : .:: .*: : . . : :: **** . :: . .* * : * ..*: .* :***: ...* ** ** * ** : .: * . * *:** *****:* * .**:************* **: :****** **::** **.: :*****.******:*:*:*: : :::::* *::**:*:***:****:**.:**::::*:*:: *.*.::.: . *** :::*:*.** ***..* : **** ** :**** **: ******:*:****.****:******** :***:*:**:**:*** *:*::***..: : ***********::********* ***:.* * :.: *:.*.: ", "identical_positions": 598, "similar_positions": 450, "identity": "27.26%" }, { "cls_id": "homologset.agr.MGI:2444678", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9V0-1", "uniprot_id": "D4A9V0_RAT", "id": "D4A9V0-1", "name": "serine C-palmitoyltransferase", "aln": "MANPRDS---------AVTNG-------------------------------TLRNPKTQPGKRQSTD------------CVKNGISK-------EAQQNRKAEEDDKLVFKP-YPEPPLYVFVFTYMGYGIGMLFGYLRDFMRNWGIEKCNAAVEREEQKDFVPLYQDFENFYTRNLYMRIRDSWSHTVCSVPVPNFDIMEKVTDDYNWTFRHTGKVIKNVINMASYNYLGLASKYNESMEKVKDTIEKYGVGVASTRNEMGSLDIHNELEDLMAKFLNVEAVMVFGMGFATNSTNIPIFVGKGCLILSDEFNHTSVILGSRLSGAVIRPFKHNNIQNLEKLLREAIIRGQPRTG-RAWKKILILVEGVYSMEGSIVNLPQIVALKKKYKAYLYMDEAHSIGCTGTMGQGIRELFGLAPEDIDIYMGTFTKSFAASGGYIAGKKEIVDYVRVQSHSATYATSMSPVVAAQIIRSLKIMMGYEGNFGGVQRIQQLRENIKYFRRRLIEMGFIIYGNDYSPVVPVLLYMPAKVSAFGRLLLKKKIAVVVVGFPATSLPEGRARFSLSSAHTREMLDTVLEVVDKIGDLLNVKYFPYKK--SGRAVLYNKENFDNEASFEEKSSEPEA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG54-1", "uniprot_id": "SPTC3_MOUSE", "id": "Q8BG54-1", "name": "Serine palmitoyltransferase 3", "aln": "MANLNDS---------AVTNG-------------------------------TLHNPKTQQGKRQSTG------------CVKNGISK-------EAQQNRKAYAEDKPVFEP-YQEAPLYVYVLTYMGYGIGILFGYLRDFMRNWGIEKCNAAVEREEQKDFVPLYQDFENFYKRNLYMRIRDSWSHTVCSAPEPYMNVMEKVTDDYNWTFRHTGKVIENIINMASYNYLGLAGKYDDSMVRVKDTLEKYGVGVASTRNEMGTLDIHKELEDLMAEFLNVEAVMSFGMGFATNAMNIPVFVGKGCLILSDEFNHTSVILGSRLSGAVIRPFKHNNAENLEKLLREAIIRGQPGTG-RAWKKILIVVEGVYSMEGSIVNLAQIVALKKKYKAYLYIDEAHSIGCTGPTGRGVRELFGLDPEDIDVYMGTFTKSFSGSGGYIGGKKEIVDYLRMQSHSTTYATSMSPVVAAQLIRSLKITMGYEGNIGGMERIQQLKENIKYFRRRLKEMGFIIYGNDFSPVIPVLLYMPAKVSAFSRFLLKKKISVVVVGFPATSLPEGRARFSMSSAHTREMLDTVLEVVDELGDLLNVKYFPLKK--SGRAILYNKEGFDNEASFEEMHSEPEA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUV7-1", "uniprot_id": "SPTC3_HUMAN", "id": "Q9NUV7-1", "name": "Serine palmitoyltransferase 3", "aln": "MANPGGG---------AVCNG-------------------------------KLHNHKKQSNGSQSRN------------CTKNGIVK-------EAQQNGKPHFYDKLIVES-FEEAPLHVMVFTYMGYGIGTLFGYLRDFLRNWGIEKCNAAVERKEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSAPGPLFDLMERVSDDYNWTFRFTGRVIKDVINMGSYNFLGLAAKYDESMRTIKDVLEVYGTGVASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDAVIYGQPRTR-RAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAEQIIRSLKLIMGLDGTTQGLQRVQQLAKNTRYFRQRLQEMGFIIYGNENASVVPLLLYMPGKVAAFARHMLEKKIGVVVVGFPATPLAEARARFCVSAAHTREMLDTVLEALDEMGDLLQLKYSRHKK--SARPELYDETSFELED------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q9N3-1", "uniprot_id": "A0A8M9Q9N3_DANRE", "id": "A0A8M9Q9N3-1", "name": "serine C-palmitoyltransferase", "aln": "MIRTEEL---------HSCNG-------------------------------TLKSRSGQ--KQTENY------------TLKNGYHKNE-----KVQKNGNGFHQPRVRGEDSFEEAPMYVAVLTYMGYGIVILFGYFRDFLRAVGLEKCHQAQEREEQKDFVPLYQDFENFYKRNLYMRVRDNWNRPICSLPGPVFDLMERVSDDYNWTFRLTGRTIENVINMGSYNYLGFAENNVDFLKTVAEKTRQYGVGVCSTRQELGNFSIHEELEHLVADFLGVESAMAFGMGFATNSMNIPALVGKGCLILSDELNHTSLILGARLSGATIRVFKHNNMQSLEKLLKEAICSGQPRTH-RSWKKILIMVEGIYSMEGSLVRLPEIIALKKKYKAYLYLDEAHSIGAVGPTGRGVTEHFGVDPKEIDVLMGTFTKSFGATGGYIAGKKELVDYLRCHSHSAVYATAMSPPVVEQIIRAIKCIMGVDGTTEGQRRVRQLAENTHYFRSRLKEMGFIIYGNKDSPVIPLLLYQPGKVGAFSRAMLKRKIGVVVVGFPATTITEARARFCVSAAHTRDMLNKVLQSLDELGDYIRVKFSRHRR--PYRPELYNVTNFGLDS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3F2-1", "uniprot_id": "Q9V3F2_DROME", "id": "Q9V3F2-1", "name": "serine C-palmitoyltransferase", "aln": "MGNFDGDSGTVFEQSYATTNGNGKVPNGNGAADLSAPEKQELLRKFSAPAYTEIRTRRCQPKPANDAQSPSSINYHPEKKSIPNGHASILDQESKPNQAEGKLSPELEHFQKTSFEEVPLHTACLTYLGFYLLMILGYINQLLFVP-----KVATEK-GRDGYVALYDAFESFYSRYVYRRIKDCWNRPICSVPGDELTLKDRVTDDYGWSFKFTGTETR-CLNLGSYNYLGFAAATGQCADDSEESARSSGLAYCSSRCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASIILGLRLSGATTKVFKHNNMRDLERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCYAASISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGVITYGHEDSPVVPMLVYLFSKIGAVVRTLTTRHIAAVGAGFPATPIMEGRIRFCLSAAHTKEQLDFALEAIDEIADDLGLKYSRKPR--DPNPVIY---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40970-1", "uniprot_id": "LCB2_YEAST", "id": "P40970-1", "name": "Serine palmitoyltransferase 2", "aln": "MSTPANYTRVP------------------------------------------LCEPEELPDDIQKEN--------------EYGTLDS------PGHLYQVKSRHGKPLPEPVVDTPPYYISLLTYLNYLILIILGHVHDFLGMTFQK--NKHLDLLEHDGLAPWFSNFESFYVRRIKMRIDDCFSRPTTGVPGRFIRCIDRISHNINEYFTYSG-AVYPCMNLSSYNYLGFAQSKGQCTDAALESVDKYSIQSGGPRAQIGTTDLHIKAEKLVARFIGKEDALVFSMGYGTNANLFNAFLDKKCLVISDELNHTSIRTGVRLSGAAVRTFKHGDMVGLEKLIREQIVLGQPKTN-RPWKKILICAEGLFSMEGTLCNLPKLVELKKKYKCYLFIDEAHSIGAMGPTGRGVCEIFGVDPKDVDILMGTFTKSFGAAGGYIAADQWIIDRLRLDLTTVSYSESMPAPVLAQTISSLQTISGEICPGQGTERLQRIAFNSRYLRLALQRLGFIVYGVADSPVIPLLLYCPSKMPAFSRMMLQRRIAVVVVAYPATPLIESRVRFCMSASLTKEDIDYLLRHVSEVGDKLNLKSNSGKSSYDGKRQRWDIEEVIRRTPEDCKDDKYFVN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . * . : . : * : :**:.: : ::*:..::: : : :.. .. :. **.** * : *: * :.:. . * : ::::.: . * :* :*:.***:**:* : : . ..* ::* . : * * * ::. * .: *.**:.**: : ::. .*::*** **:*: * *****. : ***.: .**::::: : *:* . :.*.*::* .**::****:: .*.::: ******.**::*****:*. *. *:*: : *.: *.::*: ********..:***:.. : ::* :* . : *: ::.. : * : ::: * * .::::: * :*:* * .:*.* ** :.*:*:*:* .*: *. * : ::*..* ..:***.: *.* **.:*:: *:: :: *. :.::.* : :* . : ", "identical_positions": 130, "similar_positions": 191, "identity": "20.73%" }, { "cls_id": "homologset.agr.MGI:2444679", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K1H7-1", "uniprot_id": "T11L2_MOUSE", "id": "Q8K1H7-1", "name": "T-complex protein 11-like protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPFNGEK------QCVSEDQQSDSESSRFAEGVASLSDYECSRQSFTSDS-----------SSKSSSPASTSPPRGLMFDDVMAAAKNLSDMTLAHEIAVNENFQLKQNALPENSLAGQVKRVVHQAFWDVLEADLSAEPP-------QYEYAIKLFEEIREILLSFLTPGGNRLHSQICEVLDIDLIRQQAEHSAVDIQGLANYVITTMGKICAPVRDEDIRELK---------ATT-NIVEMLRQIFRVLDLMRMDMMNFVIRNIRPHIQHHLVEYERNKFQEVVEETPN--ALSQTTEWLKESIDKELL--SETDVAPAAEHSSTPSLSPLLVLNNCYLKLLQWDYQKKVLPETLMTDGPRLQELSEKLNQLKMTACVALITNNMVGAVTEGLPE---------LANRLKRISAVLLEGMN------KETFNLKEALHSIGVQTCAEVN-----KALEERGSPTLNAEVQANLVGQLSSLEEKDNPVCTLMDKRIQLYMKGLLCLPSTQKSMPPVPGGLDVIQRELEVLGCQYANIVNLNKQVYGPFYANIFRKLLFRDEAVGKIDASLPTN--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q568Z0-1", "uniprot_id": "T11L2_RAT", "id": "Q568Z0-1", "name": "T-complex protein 11-like protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPFNGEK------QYVNEDQQSDSESSRFSESTASLSDYGCSRQSFTSDS-----------SSKSSSPASTSPPRGIMFDDVMAAAKNLSDMTLAHEIAVNENFQLRPNALPENSLAGQVKRVVHQAFWDVLEADLSAEPP-------QYEYAIKLFEEIREILLSFLTPGGNRLHSQICEVLDIDLIRQQAEHSAVDIQGLANYVISTMGKICAPVRDEDIRELK---------ATT-NIVEMLRQIFRVLDLMRMDMTNFVIRNIRPHIQHHLVEYERNKFQEVLEETPN--ALSQTTEWLKESIDKELF--SETDVAPGAEHSSTPSLSPLTVLNNCYLKLLQWDYQKNVLPETLMTDGPRLQELTEKLNQLKMIACVSLITNNMVGAVTEGLPE---------LANRLKRISAVLLEGMS------KQTFNLKEALNSIGVQTCAEVN-----KALKERGSPTLNAEVQANLVGQFTSLEEKDNPVCALMDKRIQLYMKSLLCLPSTQKSRPPVPGGLDVIQQELEVLGCQYANIVNLNKQVYGPFYANIFRKLLFRDEAMGKIDASLPTN--------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N4U5-1", "uniprot_id": "T11L2_HUMAN", "id": "Q8N4U5-1", "name": "T-complex protein 11-like protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPFNGEK------QCVGEDQPSDSDSSRFSESMASLSDYECSRQSFASDS-----------SSKSSSPASTSPPRVVTFDEVMATARNLSNLTLAHEIAVNENFQLKQEALPEKSLAGRVKHIVHQAFWDVLDSELNADPP-------EFEHAIKLFEEIREILLSFLTPGGNRLRNQICEVLDTDLIRQQAEHSAVDIQGLANYVISTMGKLCAPVRDNDIRELK---------ATG-NIVEVLRQIFHVLDLMQMDMANFTIMSLRPHLQRQLVEYERTKFQEILEETPS--ALDQTTEWIKESVNEELFSLSESALTPGAENTSKPSLSPTLVLNNSYLKLLQWDYQKKELPETLMTDGARLQELTEKLNQLKIIACLSLITNNMVGAITGGLPE---------LASRLTRISAVLLEGMN------KETFNLKEVLNSIGIQTCVEVN-----KTLMERGLPTLNAEIQANLIGQFSSIEEEDNPIWSLIDKRIKLYMRRLLCLPSPQKCMPPMPGGLAVIQQELEALGSQYANIVNLNKQVYGPFYANILRKLLFNEEAMGKVDASPPTN--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGW3-1", "uniprot_id": "Q5RGW3_DANRE", "id": "Q5RGW3-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPLNDERPTSTSSTVASEDQSSDTESSERCDSLTSSSDVDCSRQSFTSDS-----------SSKHNSPS-CSPPKILTLDEVMASARDLSNLSLAHEIVVNRNFHLEPPDLPQNSLEKRVKDMVHKAFWDCLESELNDDPP-------EYDYAIKLLEEIRDTLLSFLNPGANRLRTQIMEVLDMDLIRQQADNNAVDIQGLVSYIINTMGKFCAPVRDDEIKKLK---------ENSGDCVTLFKEIFRVLDLMKMDMVNFTIQSFRPELQRQSVEYERAKFQSILERTPN--ALEHTTEWIKSSIEEATQIMPPAEKSSDSGQSGRPLPGPSLVLNTAYIKLLTWDDSKGPLPETVMTDEARLQVMQRSLQLYQTVASVLLIVYSSIGGAVSGLPA---------LAERLKKMTVVLLEGMH------NTEFKLNEALGNVSVQICCEVN-----KSLAERNFPALPDELQATLKGQICDVTQENNPVRTLVEGRVQQYLWVVLSSSSSHRTPPPVPPGLTLIQQELMPLSLSFANLVNFNKKVYGPFYFSILKSLLFSDTQN-HIPPGPPSSPLKSK---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W461-1", "uniprot_id": "Q9W461_DROME", "id": "Q9W461-1", "name": "T-complex protein 11-like protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAQENR----------SEQSGQSGDHEEHEERRIRTDSESSVESMTR---------------FVLPSLDGTPPKIVTLDEVSSMFKNLRNMELAHEIALNPDFKLQKYEPPSDSLEGAIKKMVHKAFWDLLRVQLDRQPP-------SYDQAIRLLAEIKECFPQLLSPNNERALAHINEVLDDSVIRQQAERGTLDFRAYANFVINILSRSCSPARDEAVAALR---------KID-DVVDTFRCILELMTLMKLDMANFMLRLARTEIAANSVQYEKEKFSKYLREFHGNVGFPATEDWLQR---------------------HRSGSSDDETIYNAYMQLIDYP-ADKEFPELLRIDKERFAGLSWRAQRLILCASLISVAQGMP--IISQRRE---------NRIKLAQQLDIIVQDIK------NQDQ-VASTIESCYEQIRSFVN-----KALEQENLPALSDADQAALKNQVLKLANKTSPVPSLMAKRLDGYVRVTLR---SNGSIPPPPSGFADYQEELVAFIASFRRLVSYNHAVFGEHFHQILNKTLPGEETEATTSTASGINPGQAQTAKP-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40317-1", "uniprot_id": "SOK1_YEAST", "id": "P40317-1", "name": "Protein SOK1", "aln": "MDQPRTHSGPTTASNPAPSSTNSSSAPSATNSKQERSSSSLSKPSSVVPSKDSPDGDAIAKTQAAALKNDMKSGDTSTLDGSSQNIIPNRASMQKYIDQSSDLLSRSSGVITPSMSLNASTNATNNDSSGNSANSSDLKIPIDRDNTIFKTFDTKTGQFLKNDDNEEEIRRNNKVDSIPPKNIYTNINNPSPSPPPSSKQPPSASAPQLPPATEPHKEQAAQQQPPGNASNFLRIFSNKKMRSHSVPTILHSSLRKLSSHNQYYRNQNILLNHPTPSGISKKKFSRNHHQPYLHSNNPLSSNPLSLKRAIFLNQQISGNASTNANNDNINNSTATSMTNQSFLSSSNFDLTLEDRINYIKATPTPVPFPPINLQGLKEIDLQEILKNPQLRHDIIFDPLLQFRPN---LDGERGNKKRQLANIYWNDVQNEIYVYSKRPEIFQYNRSRLVPLFDTLRDVLLTIVP---QKESPMINNVLDTELNIQELLKGSLIMSNLSGWLADLFKHHCAPMRDPWVDKMSNKFKEAERDSSLTRLIEGLRLVFQILETMKLDIANHQIRILRPALLSNAVEFEKQYFNTLIASKRVN--LNTSLLWFDKKFNENVT------AGLVRNPSSITIPDVYNICIRSIINLLSCRKMVREYPTPLSFDHARLILLRADIRQIVCILVCRLLFQQLVANDPSMDKATKEYVIHTYSTKRLKNEIISIITDEHGNCRWTKNTMSIAVHLCKVIDDLHREYDNNGSCEQARRPQLPSLDNSKITFAKSWLSKQTQPLSEVYGVLENRVFKSLEDAIFNRSECTIDGRVKQDFVYLYNTNNGNVGSTNTLSTTTDTASVKISPSLMSPSKTSTTTPTGNAIASRGLFAATELEEFENVYRHLYALINLHWSVFGPHYIEMLGDKVNKKGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .: .:: : : : :*: .. ** : . . * : * *:* .: :::. .. * : : :*: : :: . . . : *: ::: : :: :: * :*** .: *: ..:: : .:: : : *:* ** : : : :: ::.:: *::*: *. : *. : : *::*: *. : : : *:. . . . ::*: * : * *: : . : :* . :: . : : : . : : : . *:* : . . . : . : :: *: : : .: . . : . .. . .:: . ", "identical_positions": 35, "similar_positions": 139, "identity": "3.83%" }, { "cls_id": "homologset.agr.MGI:2444680", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZRH3-1", "uniprot_id": "A0A8I5ZRH3_RAT", "id": "A0A8I5ZRH3-1", "name": "10-formyltetrahydrofolate dehydrogenase", "aln": "MLWRGSQALRHFSTGRVYFKNKLKLALIGQSLFGQEVYSHLL-KEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKFPRWRVKGKTIKEVAEAYQSVGAELNVLPFCTQFIPMDIIDSPEHGSIIYHPSLLPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVKPNDTVDSLYNRFLFPEGIKAMVEAVQLIADGKAPRTPQPEEGATYEG-IQKKENAEIPWDQPAEVLHNWIRGHDKVPGAWAEIDG-----QMVTFYGSSLLTS-SVPAGEPLDIRGAKKPGLVTKNGLVLFGNDGKALMVRNLQFEDGKMIPASQYFSSGE-TSVVELTAEELKVAETIKVIWARILSNVPVIEDSTDFFKSGASSMDVARLVEEIRQKCGGLQLQNEDVYMARKFGDFIQKVVRRLRGEDQ---EAELVVDYVSKEVNEMTVKMPYQCFINGQFVDAEDGETYATINPTDGTTLCRVSYASLADVDRAVAAAKDAFENGEWGRMNARDRGRLMYRLADLMEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKI-QGSTIPINQARPNYNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTVKAGFPKGVINIIPGSGGVAGQRLSQHPDIRKLGFTGSTSVGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEEAIHDEFVTRVVEEIK-KMKIG---DPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQ---RPGFFMEPTVFTGVEDHMYLAKEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDISKAMYVSDRLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K009-1", "uniprot_id": "AL1L2_MOUSE", "id": "Q8K009-1", "name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "aln": "MLWRGSQALRHFSTSRVYFKNKLKLALIGQSLFGQEVYSQLL-KEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKFPRWRLKGKTIKEVAEAYQSVGAELNVLPFCTQFIPMDVIDSPKHGSIIYHPSLLPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVKPNDTVDSLYNRFLFPEGIKAMVEAVQLIADGKAPRTPQPEEGATYEG-IQKKENAEVSWDQPAEGLHNWIRGHDKVPGAWAEING-----QMVTFYGSSLLTS-SVPSGEPLDIRGAKKPGLVTKNGLVLFGNDGKALMVRNLQFEDGKMIPASQYFSAGE-TSVVELTAEELKVAETIKVIWARILSNTPVIEDSTDFFKSGASSMDVVRLVEEIRQSCGGLQLQNEDVYMATKFGDFIQKVVRRLRGEDE---EAEMVVDYVSKEVNGMTVKIPYQCFINGQFVDAEDGETYATVNPTDGTTICRVSYASLADVDRAVAAAKDAFENGEWGRMNARDRGRLMYRLADLMEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKI-QGSTIPINQARPNYNLTFTKKEPLGACAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTVKAGFPKGVINIIPGSGGVAGQRLSQHPDIRKLGFTGSTSVGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDLEKAVRMGMGAVFFNKGENCIAAGRLFVEEAIHDEFVTRVVEEIK-KMKIG---DPLDRSTDHGPQNHRAHLEKLLQYCETGVQEGATLVYGGRQVQ---RPGFFMEPTVFTGVEDHMYLAKEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDINKAMYVSDKLEAGTVFINTYNKTDVAAPFGGMKQSGFGKDLGEEALNEYLKIKTVTLEY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3SY69-1", "uniprot_id": "AL1L2_HUMAN", "id": "Q3SY69-1", "name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "aln": "MLRRGSQALRRFSTGRVYFKNKLKLALIGQSLFGQEVYSHLR-KEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKLPKWRVKGKTIKEVAEAYRSVGAELNVLPFCTQFIPMDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEG-IQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEING-----QMVTFYGSTLLNS-SVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALTVRNLQFEDGKMIPASQYFSTGE-TSVVELTAEEVKVAETIKVIWAGILSNVPIIEDSTDFFKSGASSMDVARLVEEIRQKCGGLQLQNEDVYMATKFEGFIQKVVRKLRGEDQ---EVELVVDYISKEVNEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFENGEWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKI-QGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIK-KMKIG---DPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQ---RPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RK21-1", "uniprot_id": "A0A8M1RK21_DANRE", "id": "A0A8M1RK21-1", "name": "10-formyltetrahydrofolate dehydrogenase", "aln": "MLWTANTIMRKFSSSSVYYQNKLKLALIGQSLFGQEVYTNLR-KQGHKVVGVFTVPDKDGKADPLAVVAEKDGTPVFKFPRWRVKGKPIPEVVEAYKAVGAELNVMPFCSQFIPMNVIDFPKHGSIIYHPSILPKHRGASAINWTLIEGDKKAGFSVFWADDGLDTGPILLQKECQVEPNDTVDTLYNRFLFPEGIKAMVEAVQLIANGKAPKIPQSEEGASYEG-IQKKSNAKVNMAQPAEAIHNWIRGHDKVPGAWVVMDG-----KPVTVYGSSVLSG-SVPAGQPIDIEGASQPGLITKSGLLLFGSDGKALQVKSLQFEDGKMIPASKYFSSEE-SASLDLTDDEKKMAEEIRAIWKGILSNVAAIEETTDFFKCGAASMDVVRLVEEVKQKCAGVQLQNEDVYMATTFQSFIQMLVRRLRGEDQ---EEEMLIDYATKEVNNMTVKMPYQCFINGKFEDADDGKTYNTVNPTDGSVICKVSYASVADVDKAVSAAKEAFDNGPWGKMNPRDRGQLLYRLADLMEEHQEELATIETIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKI-QGSTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTIKAGIPKGVINIVPGSGGLVGQRMSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDMDKAVRMGMSSVYFNKGENCIAAGRLFVEESIHDEYIRRVVEEIK-KMKIG---DPLDRSTDHGPQNHKAHMDKLVEYCEIGVKEGATLVYGGRQVD---RPGFFMEPTVFTDVEDHMFIAKEESFGPVMVVSKFKDGDVDGVLSRANDTEFGLASGVFTRDINKAMYVSERLEAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEDALHEYLRTKAVTVEY----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIC9-1", "uniprot_id": "Q9VIC9_DROME", "id": "Q9VIC9-1", "name": "10-formyltetrahydrofolate dehydrogenase", "aln": "------------------MALKMRIAIIGQSNFAADVLELLLDRSNIQIVGVFTIPDKGSREDILATTATIHNIPVFKFACWRRKGVALPEVLEQYKSVGATLNVLPFCSQFIPMEVINGALLGSICYHPSILPRHRGASAISWTLIEGDEVAGFSIFWADDGLDTGPLLLTRQTNVESTDTLDTIYKRFLYPEGVKAMGVAVDMVASGTAPKIIQPEVGATYDPAMFKTENQVINLQATAEKIWNFVRGLDSVPGAIATVLHGNGTEEQIRLFGAHLYSAGPVSNGKVLRLRGLTKTAWIHSGGLLIEGTDGAFVNIRRIKRG-TKVISASEWFKQAEDQSITDFSEDELVKRSLLAGIWKAILK--EDVESSTDFFASGAGSMDVVRLVEEVKEAFD-VPLQNEQVFMAPVFEEFFSLLVRFLRQGSAGFGNQQLDFEAFTLKANKREIRVPTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFY-GSWRQITPRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKI-QGNTIPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLR-TMTIG---DPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLVYGGCRVPN--LKGYFFTPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGTVFVNVYNKTDVAAPFGGFKQSGYGKDLGQEALNEYLKTKCVTVEY----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54114-1", "uniprot_id": "ALDH3_YEAST", "id": "P54114-1", "name": "Aldehyde dehydrogenase [NAD(P)+] 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTLYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFD-NVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNMGETIPLTFN----KFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTN--YDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRESGDTGVDNYLQIKSVHVDLSLDK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47771-1", "uniprot_id": "ALDH2_YEAST", "id": "P47771-1", "name": "Aldehyde dehydrogenase [NAD(P)+] 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTLYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFD-NVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGATIPLTFN----KFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTN--YDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGRELGQSGVDTYLQTKAVHINLSLDN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * ***.:* :. .* :**: : . *. ***:** **: ** . * : ...:** : .* .*:*..:: **::*::*:* : * .:. :: **:** **: * ***:. :::* * *:*. . : ****** * . * ..:***** ::***: .*: * ** * :**:* **:*::** *. .*: :. * : *:.***** :* ::::.. ****. :** ***** ::* *.:::**: .:::*.*: * * .*::*:. *:*::: :. : : :. **:*.. ** :: ::: .: . * * :: .. *:*: **:**.* : : ::* ***::::*** . *. :. ** * :****.***:*: ** .: ::****::* *. :. .****.* ** *:: *: .:. **: * * :: ", "identical_positions": 160, "similar_positions": 164, "identity": "16.9%" }, { "cls_id": "homologset.agr.MGI:2444681", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BMT9-1", "uniprot_id": "HHAT_MOUSE", "id": "Q8BMT9-1", "name": "Protein-cysteine N-palmitoyltransferase HHAT", "aln": "-----------------------------------------------------------------------------MLPGWELTLCLLVSLGFHFRSFYEVYKVSREHEEELDQEFELEMDTLFGG-LKKDPTDFEWNFWMEWGKRRLVWLFIGHMAVSQLATLLTKKHRPWIVMVYGMWACWCVLGAPGVVMVLLHSTIAFCVAQFR---------SVLLSWLCSL---LLLSTLR------LQSVEEVKRRWYKTENEYYLLQFTLTVR-CLYYTSFSLELCRQPPSAQPTP-------------------------------------SAQGASHSYPWLLTYVFYYPVFHNGPILNFPEFFRQMQQPELNSLQHSLCIVAKGLGRLLCWWWLAELMVHLMYMHALYSSAPLLESVS-CWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPP-LPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRLHALLAACSTSMLILFNLVFLGGIQVGKTYWNRIFLQGWPWVTLSVLGFLYCYSHVDIAWAQTYTVL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GIY5-1", "uniprot_id": "A0A8I6GIY5_RAT", "id": "A0A8I6GIY5-1", "name": "", "aln": "MYRAPANPLSRQPGATSQAKAFTPAASDRRSPQPSRVLPGPGLRAAGCRDAFFPAHSALHAAIQKLSTLHWEAESPAMLSRWELTLCLLVSLGFHFRSFYEVYKVSREHEEELDQEFELEMDTLFGG-LKKDPTDFEWNFWLEWGKQRLVWLLLGHMAVSQLATLLTKKHRPWIIMIYGMWACWCVLGAPGVVMVLLHTTIAFCVAQFR---------SMLLSWLCSL---LLLSTLR------LQSVEEVKRRWYKTESEYYLLQFTLTVR-CLYYTSFSLELCRQPP-------------------------------------------SAQRACFSFPWLLTYVFYYPVFHNGPILNFPEFFRQMQQPELSSLQHSLCILAKGLGRLLCWWWLAELMVHLMYMHALYSSIPLLESVS-CWTLGGLALAQVLFFYVKYLVLFGAPALLMRLDGLTPPP-LPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTAMTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLQTPCVRETLARHLSPQARRRLHALLASCSTSMLILFNLVFLEGIQVGKTYWNRIFLQGWPWVTLSVLGFLYCYSHVGIAWAQTYTVL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5VTY9-1", "uniprot_id": "HHAT_HUMAN", "id": "Q5VTY9-1", "name": "Protein-cysteine N-palmitoyltransferase HHAT", "aln": "-----------------------------------------------------------------------------MLPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGG-LKKDATDFEWSFWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLHTTISFCVAQFR---------SQLLTWLCSL---LLLSTLR------LQGVEEVKRRWYKTENEYYLLQFTLTVR-CLYYTSFSLELCWQQL-------------------------------------------PAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVS-CWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPA-LPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLGFLYCYSHVGIAWAQTYATD--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08929-1", "uniprot_id": "GUP2_YEAST", "id": "Q08929-1", "name": "Membrane-bound O-acyltransferase GUP2", "aln": "--------MSMLRIWSCIVHFFSVQALDSRIKPDIEFKRRQRIFINSSKEENGSSSSAVTVTRNPV--LSSNSPSPPLWNTWEFRLYYLAFTVVVPFMIKAALATSSESNPNYYKFSGLLAHGWILG-RKVDNSDPQYRFFRSN-FFLLAILILLQIILKKVFVKFSKIPKTKFDFACGLVFVCFMYGIN-SVKLFTHAFIFFTLAHSLKRKRLIAAFAIWSYGIFTL---FINQKMKNLPFNNIAIILSPMDQWYKGIVPRWDFFFNFTLLRLLSYSMDFLERWHEQLSRQPSIDYDDRRPEFRKSLSGSTLQTIYESGKNVLEEKERLVAEHHIQDYNFINFIAYITYAPLFLVGPIITFNDYLYQSENKLPSLTKKNIGFYAL---KVFSSLLLMEIILHYIYVGAIARTK-AWNNDT-PLQQAMIALFNLNIMYLKLLIPWRLFRLWAMVDGIDAPENMLRCVDNNYSTVGFWRAWHTSFNKWVIRYIYVPFGGSNN----KILTSFAVFSFVAIWHDIQLRVLFWGWLTVL---------LLLGETYITNCFSRYRFRSWYRFVCGIGAAINICMMMIINVYGFCLGAEGTKLLLKGIFNNSHSPEFLTAVMVSLFIAVQVMFEIREEEKRHGINLKC", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53154-1", "uniprot_id": "GUP1_YEAST", "id": "P53154-1", "name": "Membrane-bound O-acyltransferase GUP1", "aln": "--------MSLISILS---PLITSEGLDSRIKP-------------SPKKD------------------ASTTTKPSLWKTTEFKFYYIAFLVVVPLMFYAGLQASSPENPNYARYERLLSQGWLFG-RKVDNSDSQYRFFRDN-FALLSVLMLVHTSIKRIVLYSTNITKLRFDLIFGLIFLVAAHGVN-SIRILAHMLILYAIAHVLKNFRRIATISIWIYGISTL---FINDNFRAYPFGNICSFLSPLDHWYRGIIPRWDVFFNFTLLRVLSYNLDFLERW-ENLQKKKSPSYESKE----------------AKSAILLNERARLTAAHPIQDYSLMNYIAYVTYTPLFIAGPIITFNDYVYQSKHTLPSINFKFIFYYAV---RFVIALLSMEFILHFLHVVAISKTK-AWENDT-PFQISMIGLFNLNIIWLKLLIPWRLFRLWALLDGIDTPENMIRCVDNNYSSLAFWRAWHRSYNKWVVRYIYIPLGGSKN----RVLTSLAVFSFVAIWHDIELKLLLWGWLIVL---------FLLPEIFATQIFSHYTDAVWYRHVCAVGAVFNIWVMMIANLFGFCLGSDGTKKLLSDMFCTVSGFKFVILASVSLFIAVQIMFEIREEEKRHGIYLKC", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VZU2-1", "uniprot_id": "HHAT_DROME", "id": "Q9VZU2-1", "name": "Protein-cysteine N-palmitoyltransferase Rasp", "aln": "---------------------------------------------------------------------MSRLPDRSLLTRCEIFVYFGVYIAYIVVGLYKIYGLRDHIVKEAKFQFPEGWSLYPFSQRRRDDSNDELENFGDFIVSFWPFYLLHVAVQGFIRWKRPRLQCLGFIGVCALALSVNLDWSS--MVLLVTLIASYYIVSLLS--------LKFLVWLLSAGWILCIN-------------VMQKNVWWTDRVGYTEYVLVIVTMSWSVLRGCSYSLSKIGAK------------------------------------------QEDLTRYSLVQYLGYAMYFPCLTYGPIISYQRFAARREDEVQNWLGFVGGVLRS-----AIWWLVMQCALHYFYIHYMSRDVRMVEMMDSVFWQHSAGYFMGQFFFLYYVVTYGLGIAFAVQDGIPAPN-RPRCIGRIHFYSDMWKYFDEGLYEFLFQNIYAELCGKRSSAAAKFGATALTFAFVFVWHGCYTYVLIWSILNFLCLAAEKVFKTFTAMPEYQRWTQRHLGAVGAQRLYAMLATQLFIPAAFSNVYFIGGQEIGDFLMRGAYLSGVGNYVALCFCSYCFFQCSELLLTKSDGRSKTKTF---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: . . : : . : * :: : : . :: : .. : .: :: : :. : : : . *: : :. . .. : * * * : ***:.: : : :. . : * ::: : : . :::: :: : **: .* **:. . :*: :. . :::.: :* . *.. . :: .*:** **. : *. * * : :: : . . * : *: : * : : : ", "identical_positions": 29, "similar_positions": 100, "identity": "4.51%" }, { "cls_id": "homologset.agr.MGI:2444684", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BP97-1", "uniprot_id": "RHBD3_MOUSE", "id": "Q8BP97-1", "name": "Rhomboid domain-containing protein 3", "aln": "-----MHAWEAPGSLSRALPLASSVLMLLLSCLWLLGAGPSLRLAPELLMEPWQVHRLLTHALGHTALPGLLLSLLLLPTLGWWQECHLGTVRFLHNSTVLALATGLLAVLLAGLGVSGAAGGCGYMPVHLAMLAGQSHHP--GWPQRTLPPWLLPWLLLALTLLLSSEPPFLQLLCGLLTGLAYAAGAFQWLELSEQRLQVLQEGVLCKSLARCWPLRLFPTPGSLGELPVTYPAGVRPATPRPPYLASSDSWPHSDGSAQLPPRLGPGQLTWK-NSERGLDWAGSSFASATTMWAALDEQMLQEGIQASLLDVSVQGSQSSLWLPKPSVSSLRLQQLQHMGFPTEQAAVALAATGRVEGAVSLLVEGLVDTEALVTEGRSSPAHCTGTGAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q642B3-1", "uniprot_id": "RHBD3_RAT", "id": "Q642B3-1", "name": "Rhomboid domain-containing protein 3", "aln": "-----MHAWDPPASLSRALPLASSVLMLLLSCLWLLGAGPSLRLAPELLTEPWQVHRLLTHALGHTALPGLLLSLLLLPTLGWWQECHLGTLRFLHNSAVLALATGLLAVLLAGLGLSSAAGGCGYMPVHLAMLAGQSYYP--GWPQRTLPPWLLPWLLLALTLLLSSEPPFLQLLCGLLAGLAYAAGAFRWLELSERRLQVLQEGVLCRTLAGCWPLKLLPTPGSLGELPVTYPAGVRPATPRPPYLASSSSWPHTDGFAQLPPGLGPGQLTWK-NSERDLDWAGPSFASATPMWAALDEQMLQEGIQASLLDVSVQGSQNTLWSPKPSVSSLRLQQLQHMGFPTEQAAVALAATGRVEGAVSLLVEGLVDTEALVTEERSGPAHCKDTGVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y3P4-1", "uniprot_id": "RHBD3_HUMAN", "id": "Q9Y3P4-1", "name": "Rhomboid domain-containing protein 3", "aln": "-----MHARGPHGQLSPALPLASSVLMLLMSTLWLVGAGPGLVLAPELLLDPWQVHRLLTHALGHTALPGLLLSLLLLPTVGWQQECHLGTLRFLHASALLALASGLLAVLLAGLGLSSAAGSCGYMPVHLAMLAGEGHRP--RRPRGALPPWLSPWLLLALTPLLSSEPPFLQLLCGLLAGLAYAAGAFRWLEPSERRLQVLQEGVLCRTLAGCWPLRLLATPGSLAELPVTHPAGVRPPIPGPPYVASPDLWSHWEDSALPPPSLRPVQPTWEGSSEAGLDWAGASFSPGTPMWAALDEQMLQEGIQASLLDGPAQEPQSAPWLSKSSVSSLRLQQLERMGFPTEQAVVALAATGRVEGAVSLLVGGQVGTETLVTHGKGGPAHSEGPGPP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5PMS4-1", "uniprot_id": "A5PMS4_DANRE", "id": "A5PMS4-1", "name": "", "aln": "MLNNIFPAWMWSGSNRPGCCSGTFLILSLIVSTWLCGIHASLSLGPGGEFP--GFYDFIFYAFSNEELTSFLHNISLLLWIGPCQERRWGTFTFLTLSFISALLLPPIYALFLFVTGDEASRVSGYAAIHLALLTAQCRQVKQRRVLRFVPVWFLPWLLLIFDLFLLPSAPGLLHFYAICLGLNYNNELIEMLEQIER-----------LGACACLPKWAYIPVTSRSQLPVYNNTSTRPEPFSSAFQS--ENYSTWQQSVSEWPQESP----------------------LATDSQLLEEQMLRAGILASLHDAPEG-TADKVEVPKSSVSSLRLQQLEKMGFPTEKAVVALAATGQLDGAISLLIDDQIGEETVVISKGKKSAS-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .. . .: ::: *: ** * ..* *.* .: :: :*:.: *..:* .: ** :* ** : **. ** * : ** : .*: : . *: .** .:***:*:.: :* *: ***** : :* ...* * : .: ** * :. ** *: . * * . * .:*** :..** ..: : . :. : . * * :. *:****: ** *** * . . . .*.**********::******:*.*******:::**:***: . :. *::* .* ", "identical_positions": 101, "similar_positions": 96, "identity": "25.7%" }, { "cls_id": "homologset.agr.MGI:2444688", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C9A2-3", "uniprot_id": "ENDOV_MOUSE", "id": "Q8C9A2-3", "name": "Endonuclease V", "aln": "MAHTAAERPPEETLSLWKGEQARLKARVVDRDTEAWQRDPSFSGLQKVGGVDVSFVKGDSVRACASLVVLSYPELKVVYEDSRMVGLKAPYVSGFLAFREVPFLVELVQRLQEKEPDLMPQVVLVDGNGVLHQRGFGVACHLGVLTELPCIGVAKKLLQVDGLENNALHKEKIVLLQAGGDTFPLIGSSGTVLGMALRSHDHSTKPLYVSVGHRISLEVAVRLTHHCCRFRIPEPIRQADIRSREYIRRTLGQLGVAPAQRKDRSQKEQRPNACPQGGPGALADQGRPPECDGRDSSSDRKAPEPGFQEQKDQQLEGTGHQEDSDLWPPSPAWVQSPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K5U3-1", "uniprot_id": "A0A0G2K5U3_RAT", "id": "A0A0G2K5U3-1", "name": "Endonuclease V", "aln": "MAHTATEWPPEETLSLWKGEQARLKARVVDRDTEAWQRDPSFSGLQKVGGVDVSFVKGDSVRACASLVVLSYPELKVLYEDSRMVGLKAPYVSGFLAFREVPFLVELVQRLQEKEPDLMPQVLLVDGNGVLHQRGFGVACHLGVLTELPCVGVAKKLLQVEGLENNASHKEKIVLLQAGGDTFPLIGNSGTVLGMALKSHDHSTKPLYVSVGHRISLEVAVRLTHRCCRFRIPEPIRQADIRSREYIRRTLGHRGESPAQRKDRSQKEKSTNACPAGGPGAPADQGRPPECFGRSSSTDLRDPEPGFQEQKDQQLKGTRCQEDPDLWPPSPAWV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N8Q3-1", "uniprot_id": "ENDOV_HUMAN", "id": "Q8N8Q3-1", "name": "Endonuclease V", "aln": "MALEAAGGPPEETLSLWKREQARLKAHVVDRDTEAWQRDPAFSGLQRVGGVDVSFVKGDSVRACASLVVLSFPELEVVYEESRMVSLTAPYVSGFLAFREVPFLLELVQQLREKEPGLMPQVLLVDGNGVLHHRGFGVACHLGVLTDLPCVGVAKKLLQVDGLENNALHKEKIRLLQTRGDSFPLLGDSGTVLGMALRSHDRSTRPLYISVGHRMSLEAAVRLTCCCCRFRIPEPVRQADICSREHIRKSLGLPG-PPTP---RSPKAQRPVACPKGDSGESS-----ALC-----------------------------------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *: ********** *******:*************:*****:************************:***:*:**:****.*.****************:****:*:****.*****:*********:*************:***:*********:****** ***** ***: **:***:*.*********:***:**:***:*****:***.***** *********:***** ***:**::** * .*: ** * : . *** *..* : . * ", "identical_positions": 219, "similar_positions": 41, "identity": "64.79%" }, { "cls_id": "homologset.agr.MGI:2444691", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHA6-1", "uniprot_id": "D3ZHA6_RAT", "id": "D3ZHA6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLFWHTQPEHYN--------------------QHNSGSYLRD-----------------------------------VLALPIFKQEEPQLSP----------------------------------------------------------------------ENGARLPPLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKALRTAVSNNIRPPQSIIRVVFHDRRLQYTEYQQLEGWRWSRPGDRILDIDIPLSVGILDP--RASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNENGEYT-------------------------------------EHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQEKEKYQPSYETTILTECSP-------------------WPDVP----------YQANSTPSPSYNGSPSSFGLREGNSSPN-------------HPVEPLPLGSDHLLPSASIQDAQQWLHRNRFSQFCWLFASFSGADLLKMSRDDLVQVCGPADGIRLFNAIKGRNVRPKMTIYVCQE---------LEQNQLPLPQKHDENGDNSLCVYHAIFLEELTTLELTEKIASLYS---------------IPPQHIHRVYRQGPAGIHVVVSNEMVQNFQDESCFILSTLKAESNDGYHIILKCGL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UNW5-1", "uniprot_id": "TF2L1_MOUSE", "id": "Q3UNW5-1", "name": "Transcription factor CP2-like protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLFWHTQPEHYN--------------------QHNSGSYLRD-----------------------------------VLALPIFKQEEPQLSP----------------------------------------------------------------------ENGARLPPLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVK--------------SIIRVVFHDRRLQYTEYQQLEGWRWSRPGDRILDIDIPLSVGILDP--RASPTQLNAVEFLWDPSKRASAFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNESGDYS-------------------------------------EHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQEKEKYQPSYETTILTECSP-------------------WPDVP----------YQANNTPSPSYNGSPNSFGLREGNSSPN-------------HPVEPLPLGSDHLLPSASIQDAQQWLHRNRFSQFCWLFASFSGADLLKMSRDDLVQVCGPADGIRLFNAIKGRNVRPKMTIYVCQE---------LEQNQLPLPQKQDDSGDNSLCVYHAIFLEELTTLELTEKIASLYS---------------IPPQHIHRVYRQGPAGIHVVVSNEMVQNFQDESCFILSTLKAESNDGYHIILKCGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZI6-1", "uniprot_id": "TF2L1_HUMAN", "id": "Q9NZI6-1", "name": "Transcription factor CP2-like protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLFWHTQPEHYN--------------------QHNSGSYLRD-----------------------------------VLALPIFKQEEPQLSP----------------------------------------------------------------------ENEARLPPLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVK--------------SIIRVVFHDRRLQYTEHQQLEGWRWSRPGDRILDIDIPLSVGILDP--RASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNENGEYT-------------------------------------EHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQEKEKYQPSYETTILTECSP-------------------WPDVA----------YQVNSAPSPSYNGSPNSFGLGEGNASPT-------------HPVEALPVGSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSRDDLVQICGPADGIRLFNAIKGRNVRPKMTIYVCQE---------LEQNRVPLQQKRDGSGDSNLSVYHAIFLEELTTLELIEKIANLYS---------------ISPQHIHRVYRQGPTGIHVVVSNEMVQNFQDESCFVLSTIKAESNDGYHIILKCGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QJE0-1", "uniprot_id": "E9QJE0_DANRE", "id": "E9QJE0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLFWHSHPENYQ--------------------QHAQNTYIRD-----------------------------------ALA-PFLKHEEEHQAA----------------------------------------------------------------------EIGA--SPFHYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLNG-KLVEYTDVSSKYVK--------------SIVRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDIDIPLSVGIIEP--HAHPLQLNTIEFLWDPDKNASVFIQVNCISTEFTPRKHGGEKGVPFRIQIDTFTASAHGEYT-------------------------------------EHMCSASCQVKVFKPKGADRKLKTDREKIEKKSLQDKEKYQLSYKTTVLTECSP-------------------WPEAPS--------ISSTSNTPSPAYHSAHTSYSFPEENCSPDQ------------HGEPLLPSCSDHLLPSSSTQDTQQWLHRNRFSSFCRLFSGFSGSDLLKMGRDDFIQICGPADGIRLFNAIKGRCIQPRLTVYVSQ-----------LQNRIQPHTKAVGDG-----VYHALYLEDLTVLELTEKIANLYN---------------VPSQRIHGVYRQGPKGIHVLVSDEMVQNFTEEASFTISTVKDDRNEGYHVVLK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z851-1", "uniprot_id": "A1Z851_DROME", "id": "A1Z851-1", "name": "", "aln": "MALSFLSQNSGLLDLQSIFDPQYTHHQQQQQQLLHLSHHPQHHIQQHQNQQLQQQAEQIQQHQQERTLSTKFDLNLFNELDQMEFNNLNRSQYQNNNNNNSISNNQNSNNNTNTTNGISENLNQIQNRHFISGYHHQHIGSDYEQVINFVDSPPNSEESWTESSSLIEQITIVVDGQSKDSPGPQIIDVQTIYLNSGSRKRRMDWDSLDIGQSENSPTASQSGDLPSKVAHQEKEKHKREKHSGRSSWSDDIGFDLNAEFNSNSYLNNENFLSFSPTLTTLKQEPQTDQIKPSPKVSLDNASASPSIAIAKLDEVQNSPSQAISGQDSANGSGSAANGKHDVNSGLACGCGSPQGSPLANAEYELNEKGKPQQLSVLDPAKIEIGSANGATHAEDHKFQYILAAATSIATKNNEETLTYLNQGQSYEIKLKKIGDLSLYRD---KILK--------------SVIKICFHERRLQFMEREQMQQWQQSRPGERIIEVDVPLSYGLCHVSQPLSSGSLNTVEIFWDPLKEVGVYIKVNCISTEFTPKKHGGEKGVPFRLQIETYIENTNSATASGSGGSNNSAIASGSGSSGSAAPASPERTPSAGSNGKQAVHAAACQIKVFKLKGADRKHKQDREKIQKRPQSEQEKFQPSYECTIMNDISLDLVMSATTTGCYSPEYMKLWPNSPVHIPKYDGMLPFAPSAASPATSSSPIAINSVTSTNSPTLKLMDATNMVSPQHVPADMDDYSQNIMPESTPSQVTQWLTNHRLTAYLSTFAQFSGADIMRMSKEDLIQICGLADGIRMFNILRAKTIAPRLTLYASVDGCSYNAIYLLSNTAKELQQKLFKMPGFYEFMAKASAQENGAGGAATAAAAALFNNWGMHSKYSGSGSNIFNDANKSCVYISGPSGILVTITDEVLNNEIKDGSLYALEVQAGKVILKLINKQDNN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . *::: :. ..:*:.: : .: * :* : :. * ::*:*.**** *.* ::**************:: : .* : * * :* *:::: **:****: * :*:: *: .***:**:::*:*** *: . . .**::*::*** *....:*:*:********:***********:**:*: . . : : : :*:**:**** ****** * ****::*:. .::**:* **: *::.: * **: . . .:.**: .: : . . ** * : *::::*.:: .:. *** .:*:: : *: ***:*:::*.::*::*:** *****:** ::.: : *::*:*.. :. * : :* *: : * *:. . . ** .** ** * :::*:::* .:..: :: : : ", "identical_positions": 156, "similar_positions": 165, "identity": "16.44%" }, { "cls_id": "homologset.agr.MGI:2444704", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LU14-1", "uniprot_id": "F1LU14_RAT", "id": "F1LU14-1", "name": "Sorting nexin", "aln": "-----------------------------------MSQLRRIMEEHQQEAGKESKPSSTS-----VDLQGDSPLQVEISDAVSERDKVKFTVQTKSGLPHFAQPEFSVVRQHEEFIWLHDTYVENEEYAGLIIPPAPPRPDFEASREKLQKLGEGNSSITREEFARMKQELEAEYLAIFKKTVAMHEIFLQRLAAHPTLRRDHNLSVFLEYSQDLSVREKNRKEVLGGFLKSIVRSADEVLITGISGLKEVDDFFEHERTFLVEYHTRIRDTCQRADRVMHSHKCLADNYIPLSAALSSLGTQAVNQLKRSFLKLAELFERLRKLEGRIASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKARTRNR------EVQPAESHQQLCCQRFERLSDSAKRELMDFQSRRVSSFRKNLIELAELELKHARASTLLLQNTLVALKGEP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ZJ7-1", "uniprot_id": "SNX32_MOUSE", "id": "Q80ZJ7-1", "name": "Sorting nexin-32", "aln": "------------------------------------------MEEQHQEAGNESKPSSTS-----VDLQGDSPLQVEISDAVSERDKVKFTVQTKSGLPHFAQSEFSVVRQHEEFIWLHDTYVENEEYAGLIIPPAPPRPDFEASREKLQKLGEGNSSITREEFSKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFSVFLEYSQDLSVREKNRKEVLGGLLRSIVRSADEVLITGISGLKEVDDFFEHERTFLVEYHTRIRDTCQRADRVMHSHKCLADNYIPISAALSSLGTQEVNQLKRSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKARTRNR------EVRPAESRQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAELELKHAKASTLLLQNTLVALKGEP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86XE0-1", "uniprot_id": "SNX32_HUMAN", "id": "Q86XE0-1", "name": "Sorting nexin-32", "aln": "-------------------------------------------METYAEVGKEGKPSCAS-----VDLQGDSSLQVEISDAVSERDKVKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQEVNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKARTRNR------EVRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAELELKHAKASTLILRNTLVALKGEP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "M9NDI3-1", "uniprot_id": "M9NDI3_DROME", "id": "M9NDI3-1", "name": "", "aln": "MMDGTDDSNLLNSPSTNNGATMEIASPTNPLATPPATGGAPAPSGATNGSGSATSPDSSSSAPATPAVLGENALHVEISDALSEKEKVKFTVHTRTTLPGFSKKDNNVVRQHEEFVWLHDRIEENDDYAGYIIPPCPPRPDFDASREKLQRLGEGEGNMTKEEFKKMKSELEAEYLATFKKTVAMHEVFLRRLASHPVFRVDQHLKVFLEYDQDLCAKPRKKMAIFGGFVKSLGKTTDEILLS--ATVRDVNDFFENELQFLTEYHGHLREAALRTEKMTQRHKDVGDSHQKISNALTQLSTTEKGNVETFVAKTAEIFERIKNLETRVASDQDLKLGDTLRYYQRDSDAAKALLIRRLRCLAAYEAANRNLEKARSKNKDVHAPLEVQEAETAQAEACEKFESMSACGKEELIGFRNRRVAAFKKSLVELSELEIKHAKTQYEYLRQSLLALKEIA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. .*..:* : *:..*:******:**::******:*:: ** *:: : .********:**** **::*** ****.******:*******:****:..:*:*** :**.******** *********:**:***:**.:* *::: *****.***..: ::: ::**:::.: :::** *:: : :::*:****:* ** *** ::*::. *:::: : ** :.*.: :* **:.*.* .::. . * **:***:::** *:***:****.* **** ***:*** ** ****.** ** **: *:***::*: **: **: * .*::** :* ..*.**:.*:.***::*:*.*:**:***:***::. *:::*:*** .", "identical_positions": 203, "similar_positions": 131, "identity": "44.42%" }, { "cls_id": "homologset.agr.MGI:2444706", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P60756-1", "uniprot_id": "MDGA2_RAT", "id": "P60756-1", "name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 2", "aln": "MDLVYGLVWLLTVLLEGISGQGVYAPPTVRIVHSGLACNIEEERYSERVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRITSIQRHQGGRYYCKAENGLGSPAIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGVEIYEPFFT-QGETKILKLKNLRPQDYANYSCIASVRNVCNIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAITLVCVTTGGEPMPSLTWVRSFGTLPEKIVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQDRSVTMSCRVLRAYPIRVLTYEWRLGNKLLRTGQFDSQEYTEYPLKSLSNENYGVYNCSIINEAGAGRCSFLVTGKAYAPEFYYDTYNPVWQNRHRVYSYSLQWTQMNPDAVDRIVAYRLGIRQAGQQRWWEQEIKINGNIQKGELITYNLTELIKPEAYEVRLTPLTKFGEGDSTIRVIKYTG-------------EFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRPRLEGEKARLLSPVFSIAPKNPYG--PTNSAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGECAKQDLPTKNSVDGAVGILVHIWLFPVIILISILSPRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P60755-1", "uniprot_id": "MDGA2_MOUSE", "id": "P60755-1", "name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 2", "aln": "MDLVYGLVWLLTVLLEGISGQGVYAPPTVRIVHSGLACNIEEERYSERVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRITNIQRHQGGRYYCKAENGLGSPAIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGVEIYEPFFT-QGETKILKLKNLRPQDYANYSCIASVRNVCNIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAITLVCVTTGGEPTPSLTWVRSFGTLPEKIVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGTMQMESYDGTLRIVNVSREMSGMYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQDRSVTMSCRVLRAYPIRVLTYEWRLGNKLLRTGQFDSQEYTEYPLKSLSNENYGVYNCSIINEAGAGRCSFLVTGKAYAPEFYYDTYNPVWQNRHRVYSYSLQWTQMNPDAVDRIVAYRLGIRQAGQQRWWEQEIKINGNIQKGELITYNLTELIKPEAYEVRLTPLTKFGEGDSTIRVIKYTG-------------EFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPSADRSGSKEGFYMYIETSRPRLEGEKARLLSPVFSIAPKNPYG--PTNSAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGECAKQDLPTKNSVDGAVGILVHIWLFPVIILISILSPRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z553-1", "uniprot_id": "MDGA2_HUMAN", "id": "Q7Z553-1", "name": "MAM domain-containing glycosylphosphatidylinositol anchor protein 2", "aln": "MDLLYGLVWLLTVLLEGISGQGVYAPPTVRIVHSGLACNIEEERYSERVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRITNIQRHQGGRYYCKAENGLGSPAIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRYSWRRGQEVLLQGSDKGVEIYEPFFT-QGETKILKLKNLRPQDYANYSCIASVRNVCNIPDKMVSFRLSNKTASPSIKLLVDDPIVVNPGEAITLVCVTTGGEPAPSLTWVRSFGTLPEKTVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGSMQMESYDGTLRIVNVSREMSGMYRCQTSQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQDRSVTMSCRVLRAYPIRVLTYEWRLGNKLLRTGQFDSQEYTEYAVKSLSNENYGVYNCSIINEAGAGRCSFLVTGKAYAPEFYYDTYNPVWQNRHRVYSYSLQWTQMNPDAVDRIVAYRLGIRQAGQQRWWEQEIKINGNIQKGELITYNLTELIKPEAYEVRLTPLTKFGEGDSTIRVIKYSAP------VNPHLREFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRPRLEGEKARLLSPVFSIAPKNPYG--PTNTAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGECAKQDLATKNSVDGAVGILVHIWLFPIIVLISILSPRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TGJ5-1", "uniprot_id": "A0AB32TGJ5_DANRE", "id": "A0AB32TGJ5-1", "name": "", "aln": "MDIIWALLWLLAALFEGVFCQGVYAPPTVQIIHSGHACNIEEERYTERVYTIREGETLELTCLVSGHPRPQIRWTKTAGSATDRFQDSSVFNETLRITRIQRHQGGRYYCKAENGLGTPAIKSIRVDVYYLDDPIVTVHQSIGEAKEQFYYERTVFLRCAANSNPPVRYSWRRGREFLYQGSDKGVEIYEPFFTQQGETKILKLKNLRPQDYANYTCTASVRSVCGIPDKSVLFQLTNKTASPTIKLLVEDPIVANPGQTVTLVCIISGGEPSPTLSWVRNTEELPKKSVLNGGTLTIPAISTDDAGVYSCVASNNVGNPAKKSTNIVVRALKKGRFWITPDPYHNDDNIQIGREVKISCQVEATPPEELMFSWLKNGRPLRSSERMVITQTDPDVAPGTTNLDIIDLKFTDFGTYTCVASLKNGGIPEISIDVNISSTTVPPNLTVPRGKSPLVTQEGDTVELQCLVSGKPKPIIIWSRADKEAPMPDGNMQTESYDGVLRIVNVSREMTGTYRCQTSQYNGFNVKPREAIVELIVQYPPAVEPVYTEIRQGLGRPFSLSCRVLRAHPSRVLKYEWKLGTRLLTMGQFDTRDETEYHVRALNREGYGAYTCDITNEAGAGRCTFLVTGKAFAPEFFYDTYSALWQNKPRVYGFKLQWTQMNPNAVDRIMAYRLGIKQMGHQRWWEQEIPTEDNIQKGELLSYNLTELIKPEAYQVRLTPITRFGEGDSTERIIRYSEASRDTAPVNPHWSKFHCGFEEDTICMFTQDKTEEFDWTRHSAATRDTKYTPNTGPSSDRSGSKQGFYMYIETSRPRLEGDKARLLTPSFNVAPKNPYGNVASNPTYCFSFYYHMYGKHIGTLNVYLRQKSQTGQDTSVWTLSGNQGDRWRQARVNINPTSSFQIVMEGIRGSGIEGDIAVDDVTIEEGECRDP-PPSSNIRSLASPTEVHIWQLALTLLLVLVGLRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:::.*:***:.*:**: *********:*:*** *********:******************:****************:**************** ******************:****************:************************.**************:*.* *************** ********************:* ****.**.**** * *:*:******:*****:****.***:::****: :**** *:*:***. **:* ************::****.***:*.*************:*****************:******************.*.*** ***:*********************:**************************.***.:*********:*********: ******:****:**** *:*******:*******..****.** *****.**********:* ******************:*:***********.: ***** .*..::*******:* ***.***:**.:** ****::: *** :::*..*.**.*.*.* ********:*******:****:****..:***: ***.:.********:*****:******:* *:******** :.*******::************:*****:*:******* *:*:*: :******:..**:****.*::****::*:***:*********.:******:***************:*****:* *.:******* .:*.:*****:*****:***.****** *.** :..:*: ***:*:**.:*:*** * :***:::*****.*******:***:* **** . .:.* . * **** :.: :*: ::. **", "identical_positions": 725, "similar_positions": 168, "identity": "75.13%" }, { "cls_id": "homologset.agr.MGI:2444710", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2VWP9-1", "uniprot_id": "PRTG_RAT", "id": "Q2VWP9-1", "name": "Protogenin", "aln": "MAPPVR-------PGMLP--LLLLLLLPPLGSVPGVWSFSELFFMKEPQDATVTRKDPVFLDCQAHGEGPIKVTWLKNGAKLSENKRIQVLSNGSLYISEAEGRRGEQSDEGFYQCLAVNKYGAILSQKAHLTLSTISAFEVHPVSTEVPEGGVARFSCKISSTPPAVITWEFNRTALPMTMDSRVTALPSGVLQIYDAGPEDAGKYRCVAATHAHKRKSMEASLTIVPANETRSFYMPTIIASPQNVTASLHQTVVLECMATGYPKPIISWSRLDHKSIDVFNTRVLGNGNLIISDVKLQHAGVYVCRATTPGTRNFTVAMATLTVLAPPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRRIHSNGRIKMYNSKLVINQIIPEDDAIYQCMAENSQGSVLSRARLTVVMSEDRPSAPYNVHAETMSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNEEYQVVLGNDTTHYIIDDLEPDSNYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPPEISLTSRSPTDILISWLPIPAKYRRGQVVLYRLSFRLSTENSIQVVELPG---TVHEYLLEGLEPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAPKSPELHLEPLNCTTISVRWLQDTEDPAAIRGYKLFYKEEGQQEHGPIFLDTGDLLYTLSGLDPRRKYHVRLLAYNNLEDGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSSSIFLHWRRPAFTTAQVINYTIRCNPVGLQNASLVLYLQTSETHMLVQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHTTLPEAPTGPPVGVKVTLIEDDTALVSWKPPDG-PETVVTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGEGPFPNSVELAVLPKDASESNQRPKRLDSSDAKVYS-GYYHLDQKSMTGIAVGVGIALTCILICVLILIYRSKARKSSASKTTQSGTQPLSRASASVAAGSDMGKNLERATENEESSVP-MMPSCFIDAKGGTDLIINSYGPIIKNNPKKK---WRFFQDTKKIKVEQTQRRITQTVCFYQPGTTVLISDEDSPSSPGQTTSFPRPFGPTTLDTEHSANSEGSHETGDSGRFSHESNDEIHLSSVISSTPPTSNSLTCGDSDGDAAPKKHGDPAQPLPAEQTSAPQPTPAGLRHAAESVPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2EY15-1", "uniprot_id": "PRTG_MOUSE", "id": "Q2EY15-1", "name": "Protogenin", "aln": "MAPPVR-------PGMLP--LLLLLLLPPLGSVPGVWSFSELFFMKEPQDATVTRKDPVVLDCQAHGEGPIKVTWLKNGAKLSENKRIQVLSNGSLYISEVEGRRGEQSDEGFYQCLAVNKYGAILSQKAHLTLSTISAFEVHPVSTEVHEGGVARFSCKISSTPPAVITWEFNRTALPTTMD-RVTALPSGVLQIYDVGPEDAGNYRCVAATIAHKRKSMEASLTIVAANETRSFYMPTIIASPQNVTASLHQTVVLECMATGYPRPIISWSRLDHKSIDVFNTRVLGNGNLIISDVKLQHAGVYVCRATTPGTRNFTVAMATLTVLAPPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRRIHSNGRIKMYNSKLVINQIIPEDDAIYQCMAENSQGSVLSRARLTVVMSEDRPSAPYNVHAETMSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNEEYQVVLGNDTTHYIIDDLEPDSNYTFYIVAYMPLGASQMSDHVTQNTLEDVPLRPPEISLTSRSPTDILVSWLPIPAKYRRGQVVLYRLSFRLSTENAIQVVELPG---TVHEYLLEGLKPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAPKSPELHLEPLNCTTISVRWLQDTEDPAAIRGYKLFYKEEGQQEHGPIFLDTGDLLYTLSGLDPRRKYHVRLLAYNNMEEGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSSSIFLHWRRPAFTTAQVINYTIRCNPVGLQNASLVLYLQTSETHMLVQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHSTLPEAPTGPPVGVKVTLIEDDTALVSWKPPDG-PETVVTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGEGPFSNSVELAVLPKDASESNQRPKRLDSSNAKVYS-GYYHLDQKSMTGIAVGVGIALTCILICVLILIYRSKARKSSASKTAQSGTQPLSQASASVAAGSDMGKNLERATETAESLVP-MMPSSFIDAKGGTDLIINSYGPIIKNNTKKK---WLFFQDTKKIKVEQTQRRFTQAVCFYQPGTTVLISDEDSPGSPGQTASFPRPFGATALDTEHSANSEGSHETGDSGRFSHESNDEIHLSSVISSTPPTSNPLAGGDSDGDAAPKKHGDPAQPLPAEQTSAPQ-TSAGLRYAAEGFPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2VWP7-1", "uniprot_id": "PRTG_HUMAN", "id": "Q2VWP7-1", "name": "Protogenin", "aln": "MAPPLRPLARLRPPGMLLRALLLLLLLSPL---PGVWCFSELSFVKEPQDVTVTRKDPVVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNGSLYISEVEGRRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFEVQPISTEVHEGGVARFACKISSHPPAVITWEFNRTTLPMTMD-RITALPTGVLQIYDVSQRDSGNYRCIAATVAHRRKSMEASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSRLDHKSIDVFNTRVLGNGNLMISDVRLQHAGVYVCRATTPGTRNFTVAMATLTVLAPPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKMYNSKLVINQIIPEDDAIYQCMAENSQGSILSRARLTVVMSEDRPSAPYNVHAETMSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNEEYQVVIGNDTTHYIIDDLEPASNYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPPEISLTSRSPTDILISWLPIPAKYRRGQVVLYRLSFRLSTENSIQVLELPG---TTHEYLLEGLKPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAPKSPELHLEPLNCTTISVRWQQDVEDTAAIQGYKLYYKEEGQQENGPIFLDTKDLLYTLSGLDPRRKYHVRLLAYNNIDDGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSSSIFLHWRRPAFTAAQIINYTIRCNPVGLQNASLVLYLQTSETHMLVQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHSTLPEAPAGPPVGVKVTLIEDDTALVSWKPPDG-PETVVTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGEGPFSNSVELAVLPKETSESNQRPKRLDSADAKVYS-GYYHLDQKSMTGIAVGVGIALTCILICVLILIYRSKARKSSASKTAQNGTQQLPRTSASLASGNEVGKNLEGAVGNEESLMPMIMPNSFIDAKGGTDLIINSYGPIIKNNSKKK---WFFFQDSKKIQVEQPQRRFTPAVCFYQPGTTVLISDEDSPSSPGQTTSFSRPFG-VAADTEHSANSEGSHETGDSGRFSHESNDEIHLSSVISTTPPNL------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q2EY14-1", "uniprot_id": "PRTGA_DANRE", "id": "Q2EY14-1", "name": "Protogenin A", "aln": "MASFKR---------------DLYLFLAVFLSISGVWSFSELFFIKEPHDVTAMRRDAVVLDCQAHGEAPIGIRWLKNGVTITESERVYSLSNGSLLISEVESRK-DKSDEGFYQCLAQNKYGSILSQRARLTIASLSTFTQQPASIIVMEGSVARFTCKITATPPPIITWEFNRVTLPLATE-RITVLPSGVLQIQGVEQRDAGSYRCVAANIVSRRRSTEATLTVTPAMSPRAPQRPRIIAGPQNLTVPAHSTALLECMASGNPRPLISWSRADHKSIDVHKTKVLGNGNLIISDVNPQHAGIYFCRATTPGTRNYTIAAANITVLAPPSLVEWPESVTRPRAGTARFVCTAEGFPTPQITWLKNGEPVRSNGRIKMYNSKLVINQIIPEDDGIYQCEAENIQGSVLAMARLIVVMSDNRPSAPRNIRADTVSSSAIVLAWDRPAYNSEKVIAYSVHYMKAEGLNNEEYQIVIGNDTTRYIIDDLEAGRNYTFYIVAYMPMGASRMSDHVIQHTLEDVPLRAPELSLTSRSPSDIQVSWQPLSHKLSRGRVSAYRLSYRTSSDGTLTQLELSA---HKTHQLLEGLQPDTTYLLRIAAATAVGWGEPSAWSSHRTPKASSTKVPLAPELQLESLNCTTVTLRWHLPAGSSSGLQGFKLSYHEEGQSEAAQAQIPPHHRQHTIGGLDPRKKYHIKLLAFSFMGDGYQADQTISTPGCVSVRDRLVPPPPPPHHVYAHSNSSSSVFLHWARPAFTSAQTLNYTVRCNPVGLQNASLVLYLQTAAQSLLVTDLEPNTNYEFAVRLHVDLLSSPWSPVVYQTTLPEAPSRAPVGVKVTLIEGDSALVSWKAPDDRSAAAVTHYTVLYATRRAWAAGDWQMLQREGSITMALLENLQPGQVYLVQVSASNQMGDGPFSAAVELTIHTDGHAHRTHG-----FSHATVFSDGFYHLDQRSMAGIAVGVCIALTCIIICILILACRSKTRKSCTTKSIRQAGGQTPPTAVRLAN--------ESAAESVEVMMP-MMRDHFIDAKGGTNLIINSYGPVKPNIEKKRRKRWSFFK-----KNEKEVKKVSSPAYSYHPGTTLLCYTETSPENP--PTTLQGLFGPSGGDSEGSHSSEGSHETSDSGRYSHDDTEATNVS--IRSRPASLQ------DDGNQTPVHEKQLETTLQEQEMTDLHPV-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2EY13-1", "uniprot_id": "PRTGB_DANRE", "id": "Q2EY13-1", "name": "Protogenin B", "aln": "MGSVRWKT------------HQQWLIIFWILSFSGVFGFSELWFSIEPQDVSVSAGQHVVLDCQAGGESPVSVRWRENGVQIQESECVRLLSNGSLCVSNLTQQR----DEGYYQCVANNQYGAIISHRARLTITGVLVFSAHPVPLELRLGSVARFSCAVNRSP-ADISWEINQRSLPQDSD-RITVLPNGVLQIRNVTMRDAGKYRCVAANAASRVTSREAELVLIPVGGPRRLLKPLIIAGPQNISVALHQPVVLECLAEGNPRPLVSWSRADSKPIDVSAASVLGNGNLMISAVKAHHSGTYVCRATTPGTRNYTTAAGNVTVLPP-SLVEKPESQTRPRAGTARFSCQAEGTPTPQITWFKNGEVIRTNGRTKMYNNKLVITQIIPEDDAFYQCLAENSQGSVVSTSRLIVVQSENRPSAPRNIHAETISSSAILLAWERPQYNADKVIAYSIHYMKSEGLNNEEYQAVIGNDTTSHIVDDLEPARNYTFYIVAYMAMGASRMSEQVTRHTLEDVPLRTPELSLTSRSPTDILVSWQPLPPKLSRGRVSAYRLSYRTATDEQVNSVELPVSGENGTQYLLQDLQPDTIYLIRMSVSTRVGWSQPSAWSSHRTPKTSSATVPPAPNLELEPLNCTSVSVRWFPAASD-VLIQGFKLSFHPDGQSEDSITQLPPQDHQHTITALNPRVKYHVKVLAFSANGDGYQAHQTVNTPGCPSTPNRRLAALPPPDHTHAKANSSSAVHLSWGRPAFSSGKPVTFSVRYGPASPSEASSVRYIQTSEQTVMVTGLQPNTRYEFAVRLHMDQMSSPWSATVYQRTLLEAPMSPPESVKVTLIEADTALVCWKQPNQ-PNLSVTHYTVLYASQSSWLAGEWQVLQREGTNTMALLEKLESGNVYLVKISASNLAGDGPFSNTVELAVKGKPHHGKNPR-HADSHAEKTAFIDGLYHIDEKSMSGIIVGVCIALSCIILCIFILLSKTQTQKSASSKMIGSMRNEVMHNEASSAN--------QQPAENAEVLLP-MMRNHFIDAKGGSNLLINHAGPINCGSQTKR-KRWSIFNHSQ--RSNESKNETEDPACLYEVGKTVLCYEDEA------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. *:: : .**: **** * **:*.:. : *.***** ** *: : * :**. : *.: : ****** :*: :: ***:***:* *:**:*:*::*:*::: : .* :* . : *.****:* :. * . *:**:*: :** : *:*.**.***** .. .*:*.***:**. . : * ** *.: .. .: * ***.***::.. *...:***:* * *:*::**** * *.*** : *******:** *. :*:* *.**********:* * ..:***.* *:** *** ********** * *** *:*:::*:***. :::*** ****.****.*******.:*** *** ***::: :** ** *::***** *::*:*:*****:***:** **::******:****:********* *:***** :*:****. **********.:***:**::* ::********.**:*******:** :** *:. * **:* ****:* ::: : :**. . **:.*:**: **:*::.:* ** .:.*.*:******::*...* :*:*.**.****::::** . . ::*:** :: :**.* . : . . :*: .*:** ***:::**:. :****.**:.**** *. :* :.. ***.* :*::*:**::.* * ****::.: :.:::* .*.. .:** * *:**: ::* .*:***.********:* :*****..**: ** *** .* .******* *:***.** *: . **:**:***:: :* **:**:*:***: ******:* .*:**:*::**** *:***. :***:: . . :. ..: * **:*::**:** *** ***:**::*::** :::::**.::* . . * : .. . * :* :* . *******::*:** **: . .*: * :*: : :: .. .. *. *.*:* : : ", "identical_positions": 495, "similar_positions": 322, "identity": "40.88%" }, { "cls_id": "homologset.agr.MGI:2444716", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8QZV2-1", "uniprot_id": "SHSA2_MOUSE", "id": "Q8QZV2-1", "name": "Protein shisa-2 homolog", "aln": "MWGGRCSPSTSSRHRASLLQLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGVGEPGRTDREGPDSSAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQDPQQSRAPGANRLMETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHTPYVGYAVQHDSVPMTPVPPFMDGLQPGYRPVQPPFAHTNSEQKMFPAVTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZWR8-1", "uniprot_id": "D3ZWR8_RAT", "id": "D3ZWR8-1", "name": "", "aln": "MWGGRCSPSTSSRHRASLLQLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGVGEPGRTDREGPDSSAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQDPQQSRAPGGNRLMETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHTPYVGYAVQHDSVPMTPVPPFMDGLQPGYRPVQPSFAHTNSEQKMFPAVTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UWI4-1", "uniprot_id": "SHSA2_HUMAN", "id": "Q6UWI4-1", "name": "Protein shisa-2 homolog", "aln": "MWGARRSSVSSSWNAASLLQLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGAGEPGRADKDGPDGSAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQDPQQSRAPGGNRLMETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHPPYVGYTVQHDSVPMTAVPPFMDGLQPGYRQIQSPFPHTNSEQKMYPAVTV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.* *. :** : ********************************************************************************.*****:*::***.***********************************************.***************************************************************************************.*****:*********.************* :*..*.********:*****", "identical_positions": 272, "similar_positions": 18, "identity": "92.2%" }, { "cls_id": "homologset.agr.MGI:2444720", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJR6-1", "uniprot_id": "D3ZJR6_RAT", "id": "D3ZJR6-1", "name": "", "aln": "MISAPDVVAFTKEDEYEEEPYNEPALPEEYSVPLFPYASQGANPWSKLSGAKFSRDFILISEFSEQVGPQPLLTIPNDTKVFGTFDLNYFSLRIMSVDYQASFVGHPPGSAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADQHKIMQQFQELSAEFSKASECLKTGNRKAFAGELEKKLKDLDYTRTVLHTET------------------------------------------------------EIQKKANDKGFYSSQAIEKAN------------------ELANVEKSIIEHQDLLRQIRSYPRQKMKKPDLHPGDTEHTQDQADQVCPTSNPEESAN--ADLYTCRPAYTPKLIKAKSTKCFDKKLKTLEELCDTEYFTETLAQLSHIEHMFRGDLCYLLTSQIDRALRKQQPITNFLFEDFVEVDDRME-KQENVPSQPSHGRLPSKPVEECPIPKVLISVGSYKSSVESVLIKMEQELGDEEYKEVEATESSSFDPQ---ENLDYMGMDMKGSISSGESIEVLGTEKSASVLSKSDSQASLTVPLSPHVVRSKAVSHRTISEDSIEVLSTCPSEALIPDDFKASYPSAINEEEAYAD-NEGAIHFQASASSPELDETQEGNLENIPSQIDSSCCIGKESEGQLVP--LPTPAYTLSDEDGVVSIPPQRYIQKDQGLHMDFGMENTDPSPR----DNSCEMFPAYDLDPSCLLASRDISKMSLDNYSDSTSYMGSVASTSSDRIPSAPPAG----LSSERHKKRAGQNALKFIRQYPFAHPAIYSLLSGRTLVVLGEDETIVRKLVTALSIFVPNYGCYAKPVKHWISSPLHIMDFQKWKLIGLQRVASPANVGTLHTLSRYSRYTSILDLDSKTLRCPLYRGTLVPRLADHRTQIKRGSTYYLHVQSMLTQLCSKAFLYTFCHHLHLPAHSEETQEAVASRQTSFLKLNLGLVNEDIRVVQYLAELLKLHYMQESPGTTHPLLRFDYVPSFLYKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UMB5-1", "uniprot_id": "SMCR8_MOUSE", "id": "Q3UMB5-1", "name": "Guanine nucleotide exchange protein SMCR8", "aln": "MISAPDVVAFTKEDEYEEEPYNEPALPEEYSVPLFPYASQGANPWSKLSGAKFSRDFILISEFSEQVGPQPLLTIPNDTKVFGTFDLNYFSLRIMSVDYQASFVGHPPGSAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADQHKIMQQFQELSAEFSKASECLKMGNRKAFAGELEKKLKDLDYTRTVLHTET------------------------------------------------------EIQKKANDKGFYSSQAIEKAN------------------ELANVEKSIIEHQDLLRQIRSYPRQKTKIPDLQPGDTEHTQDQADQVSTTSNPEESAN--ADLYTCRPAYTPKLIKAKSTKCFDKKLKTLEELCDTEYFTQTLAQLSHIEHMFRGDLCYLLTSQIDRVLRKQQPITNFLFEDFVEVDDRME-KQENVPSQPSQDRLPPKPVEECPIPKVLISVGSYKSSVESVLIKMEQELGDEEYTGVEATEARSFDPQ---ENLDYLDMDMKGSISSGESIEVLGTEKSASVLSKSDSQASLTVPLSPHVVRSKAVSHRTISEDSIEVLSTCPSEALIPDDFKASYPSAINEEEAYAD-NEGAIHFQASAGSPEPDETQEGNLENIPSQIDSSCCIGKESEGHLVP--LPTPAYTLSDEDSVVSIPPQRYIQKDQGLHVDFGVENTDPSPR----DNSCEMFPAYELDPSCLLASRDVSKMSLDNYSDTTSYMGSAASTSSDRIPSAPPAG----LSSERHKKRAGQNALKFIRQYPFAHPAIYSLLSGRTLVVLGEDETIVRKLVTALSIFVPNYGCYAKPVKHWISSPLHIMDFQKWKLIGLQRVASPANVGTLHTLSRYSRYTSILDLDSKTLRCPLYRGTLVPRLADHRTQIKRGSTYYLHVQSMLTQLCSKAFLYTFCHHLHLPAHSEETQEAVASRQTSFLKLNLGLVNEDIRVVQYLAELLKLHYMQESPGTTHPLLRFDYVPSFLYKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEV9-1", "uniprot_id": "SMCR8_HUMAN", "id": "Q8TEV9-1", "name": "Guanine nucleotide exchange protein SMCR8", "aln": "MISAPDVVAFTKEEEYEEEPYNEPALPEEYSVPLFPFASQGANPWSKLSGAKFSRDFILISEFSEQVGPQPLLTIPNDTKVFGTFDLNYFSLRIMSVDYQASFVGHPPGSAYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADQHKIMQQFQELSAEFSRASECLKTGNRKAFAGELEKKLKDLDYTRTVLHTET------------------------------------------------------EIQKKANDKGFYSSQAIEKAN------------------ELASVEKSIIEHQDLLKQIRSYPHRKLKGHDLCPGEMEHIQDQASQASTTSNPDESAD--TDLYTCRPAYTPKLIKAKSTKCFDKKLKTLEELCDTEYFTQTLAQLSHIEHMFRGDLCYLLTSQIDRALLKQQHITNFLFEDFVEVDDRMVEKQESIPSKPSQDRPPSSSLEECPIPKVLISVGSYKSSVESVLIKMEQELGDEEYKEVEVTELSSFDPQ---ENLDYLDMDMKGSISSGESIEVLGTEKSTSVLSKSDSQASLTVPLSPQVVRSKAVSHRTISEDSIEVLSTCPSEALIPDDFKASYPSAINEEESYPDGNEGAIRFQASISPPELGETEEGSIENTPSQIDSSCCIGKESDGQLVL--PSTPAHTHSDEDGVVSSPPQRHRQKDQGFRVDFSVENANPSSR----DNSCEGFPAYELDPSHLLASRDISKTSLDNYSDTTSYVSSVASTSSDRIPSAYPAG----LSSDRHKKRAGQNALKFIRQYPFAHPAIYSLLSGRTLVVLGEDEAIVRKLVTALAIFVPSYGCYAKPVKHWASSPLHIMDFQKWKLIGLQRVASPAGAGTLHALSRYSRYTSILDLDNKTLRCPLYRGTLVPRLADHRTQIKRGSTYYLHVQSMLTQLCSKAFLYTFCHHLHLPTHDKETEELVASRQMSFLKLTLGLVNEDVRVVQYLAELLKLHYMQESPGTSHPMLRFDYVPSFLYKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FA21-1", "uniprot_id": "SMR8A_DANRE", "id": "E7FA21-1", "name": "Guanine nucleotide exchange protein smcr8a", "aln": "MIGSPDVVAFTKEDDFGDSFSDPLSLPDEFSVPLFTHAAN-ANPWTKTSYAKFSKDFILISEFSEQVGPQPLLTIPSDPKVCGTFDLNYFSLRIMSVDYQASFVGHPPGSNYPKLNFVEDSKVVLGDSKEGAFAYVHHLTLYDLEARGFVRPFCMAYISADERKIMQQFQELSSEFSKASECLKSGNRKAFANELEKKLKDLEYTRSVLHKET------------------------------------------------------ELQKMNN--GCYSTQAIEKAN------------------ELANVEKSIYEHKDLLRQITSYPSRRKRDVDFVQCEAEKPP-VMDETLKDTNPSDSAENTVETESRKSSYTPQLIKAKSAKCFDKRLKTLEELCDTSFFLQTLEQLNAVEKSFRGDLCFIYTSQIDRALVSKQRVTSFLFEAEHDWEDGGASKNFSIPSN-------NPTIPILNFSGEPLSLDSYTTCIDVDHLKPGVESGEG-----PPESSTSDITQ---ETSEAADTETKGSFSSDKSIEALG----------SVSPSSLQTNFFDGLERRSKISIPSYSDN-------------------------------------------ASSSIAVPHRRSDGNLV----QMDAACCIGQDGFIFEDP--LPELAQECCG-DTVVNQEPLSLLHGDPALQMDYILE-----------ESPNMGLTFSELNTS--VLSEEVAKINIEDVFDRTSFMS--ISTSSDRAVSPFTYGS---ALTVKQKKKAGHSALRFIRQYPFAQQAISCLLSGRTLVILGVDEGTVRKLVNALFIFVPNLGKYGETVQPWLSTPFQLTDLQRWKLIGLQRAVSPAGSSILHSLNRYSRYISILDCDNKTLRCPPYKGTLISHLADHRTQIKRGSTYFLHIQGMLTQLTAKAFLYTFCHHIHLPMDIND-QGSVTSRRTNFL-LQLGYTVEESKIIQYLSELIKQHYIHGSAKVGNPSFSFNYTTSYLYKI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6PUR7-1", "uniprot_id": "SMR8B_DANRE", "id": "Q6PUR7-1", "name": "Guanine nucleotide exchange protein smcr8b", "aln": "MIGSPDLVAFTKETDFSEITTDSSVLPEDLSVPMYPYTGD-ATPWSKISSAKLKKDFILISEFSEQVGPQPLLTVPLETKACGTFDLNYFSLRIMSVDYQTSLAGSP-GYGSFKLNFVEDSKVVLADSREGVFAYVHHLTLYDLEARGFVRPLCLAYVSSDENKIIQQFQRISTEFNKVSECLKTGNRKNFANELEVKLRDLEYTRVVLQKELNTVSVKCSSEREPILNGVHSFERNADEVKLNEKSSHTDEISPQEKDGCGNSRKVEVKLENENRSHFEHEQYGKQRKDKPDKTSCPMPLANKNDELASVEKLIQDYKSLLKQVTCYPTRKLRDSEYSPYEPDDLPQSFDLDLDSQFAGPMLECSVFTYTNTPSQTLQQINSTSSSRFDKRLKTLEELCDDYFYQQALQQLYSIERTFRGDACYLYTQQLCRNLLRNLKSTNFLFEDPCDLDDDVGLQIGQSTIQQ------PSFLPAPSFLSGPVSLESYASCVEMVPIKLELGGSSQSQVQHSTLNTPSKDNRPQVADKSPAEVEMKGEIISAP--DCQGNVESVSNLMKTSISSGDSIEVLGTERSFRSQGANTLVETAMHRPPPLSSATALEGLKQGRVPTR-----------------RTCSEDSIEVLCITESISPDELRASYPCAIDEESPEQETDEKNSSQYQEDNNEKSIYVQGKISADHENACLKKLHPSVTVTPPDCPLTLEETSFQDSCQATESATMLLLDEPSRMVPDDLSDCFSYRSTTASTTSECTFPACLPKDKREGGTRRRRGRVGRAALQFMRQFPFAVHAVFSLLSGRTLVVLGSEEAAVRRLVTALSVYLPHLTKYKDSIQPWTSTPLQLTDLLNWKLIGFDRMCSFNPSSLPHCLDHYSRYLSILDVDQKTLHCPTYSGSLINLLVEPKSHFKRGNTYFTFAQSVQSKLVTKAFLLTFSHGHPSPSRPQG-----SSGTECFL---SELHTDDKKILRYLSELIKLHFMEVTPN----VLLFSYTTTSIFKL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:**:****** :: : : **:: ***::..:.: *.**:* * **:.:*******************:* :.*. ******************:*:.* * * ************.**:**.********************:*:**:*:*:.**:****.:*:**.:.***** **** **.*** **:**:*** **:.* *:: : . :. : * . ***.*** * :::.**:*: .** :: : : : :. . . : . : .: * : *::.*:. ***:********* :: ::* ** :*: **** *:: *.*: * * : *.**** : :* : . . : : : :*: ** :.:: :* .. . * : . : **.: * : * : :. . . : : :. . .: : . .*.*.::. . . . : : : :: . :.. . :.: : : :: :: * *: . **:*: .. : ::: :.*: **:*:**:*** *: .********:** :* **:**.** :::* * ..:: * *:*::: *: .*****::* * . * *.:**** **** *.***:** * *:*: *.: ::::***.**: . *.: ::* :**** **.* * : :* ** :: ::::**:**:* *::. :. : *.*..: ::*:", "identical_positions": 290, "similar_positions": 246, "identity": "28.32%" }, { "cls_id": "homologset.agr.MGI:2444725", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L9F5-1", "uniprot_id": "A0ABK0L9F5_RAT", "id": "A0ABK0L9F5-1", "name": "", "aln": "MTVPCAALVLALGLALGHSSQGNDEDSEYSGHSTTEEDTAEEETTR-ALATVTT-EALAESANSTHIHGTSNQVEFILMVAVPLAALLILLF-AILIVIYFKSRRPKQEPSSQGSQSALQTHDLGGETLKVPIFEEDTPSVMEIEMEELDKWMNSMNRNANYECLPTLKEEKEPNLSPSDNES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4Q9-1", "uniprot_id": "TM154_MOUSE", "id": "Q8C4Q9-1", "name": "Transmembrane protein 154", "aln": "MTVPCAALVLALGLAFGQSSQGNDEESEYSGQSITEEENSEDETTRSALATVTT-EALAENVNSTHTNDTSNQVEFILMVAIPLAALLILLF-MVLIATYFKSKRPKQEPSSQGSQSALQTHELGGETLKVPIFEEDTPSVMEIEMEELDKWMNSMNRNADYECLPTLKEEKEPNPSPSDNES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P9G4-1", "uniprot_id": "TM154_HUMAN", "id": "Q6P9G4-1", "name": "Transmembrane protein 154", "aln": "MQAPRAALVFALVIALVPVGRGNYEELENSGDTTVESERPNKVTIPSTFAAVTIKETLNANINSTNFAPDENQLEFILMVLIPLILLVLLLLSVVFLATYYKRKRTKQEPSSQGSQSALQTYELGSENVKVPIFEEDTPSVMEIEMEELDKWMNSMNRNADFECLPTLKEEKESNHNPSDSES", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .* ****:** :*: .:** *: * **.: .*.: .:. * ::*:** *:* . ***: .**:****** :** *::**: :::. *:* :*.***************::**.*.:*******************************::***********.* .***.**", "identical_positions": 107, "similar_positions": 44, "identity": "58.47%" }, { "cls_id": "homologset.agr.MGI:2444730", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JT24-1", "uniprot_id": "A0A0G2JT24_RAT", "id": "A0A0G2JT24-1", "name": "", "aln": "MNPE----------SGPGHGARTPP----MFQATRGLKANLK--------DAVARPWRSLARMP-KPE-VQDLEAAAAG----HEGLLPIERSFQNAAKSNNLDLMEKLFEKKVNINAVNNMNRTALHFAVGRNNLSAVDFLLSHKARVDVADKHGLTVLHLAAWSGSFEIMLMLVKAGADQRAKSQEGMNALHLAAQNNNLHIVDYLIQDLHLQDLNQPNERGRKPFLLAAEKGHVEMIEKLV--FLNLHTSEKDKEGNTALHLAAMHGHSPVVQVLLTQWSEVNETNELNISALQTAT------------------------RN---------GHTSLVNFLLSENADSQQQKETKEPPLHLAVINNRPAVVDSLLSAQHDVDALDQRQQTPLHVAADLGNVELVETLLKAGCNLKITDKQGKTALAVAARSHHSLIVDMLIKAERYYAWRE----EHPENIQDSAVSSTLTFKQDHSLETRHVRMLLWNLAYRQLKRKDWQRLARLWSFTEDQIRAIEEQWSGNDSFHEHGYRALLIWLHGALMTQSDPAKQLYEELVRAGFPELAEKSRRFKSKTDSSSKKCAVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14DN9-1", "uniprot_id": "AKD1B_MOUSE", "id": "Q14DN9-1", "name": "Ankyrin repeat and death domain-containing protein 1B", "aln": "MNPE----------SAQGHGARAP-----MLQAARGLKANLR--------DVATRPWRSLARMP-KPE-VQDPETAAAG----HEGLLAIERSFQNAAKSSNLDLMEKLFEKKVNINAVNNMNRTALHFAVGRNSLSAVDFLLSHKARVDVADKHGLTVIHLAAWSGSFEIMLMLVKAGADQRAKNQEGMNALHLAAQNNNLHIVDYLIHDLHLHDLNQPNERGRKPFHLAAERGHVEMIEKLI--FLNLHTSEKDKDGNTALHLAAMHGHSPAVQVLLTQWSEVNESNELNVSALQTAT------------------------RN---------GHTALVNFLLGENADLQQQKESKEPPLHLAVINNRPAVVNSLLSARHDVDVLDQRRQTPLHVAADLGNVELVETLLKAGCNLKITDKQGKTALAVAARSQHSLVVDMLIKAERYYAWRE----EHRESIQDSAVSSTLTFKQDHSLETRQIRTLLWNLAYRQLKKKDWQRLARLWSFTEDQIRAIEEQWSGNDSFHEHGYRALLIWLHGALLTQLDPAKQLYEELLCAGFPELAEKIRQFKSKTDSSSKKCAVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NHY2-1", "uniprot_id": "AKD1B_HUMAN", "id": "A6NHY2-1", "name": "Ankyrin repeat and death domain-containing protein 1B", "aln": "MDPAG---------RARGQGATAGGLLLRAAAAAKGLREDLW--------GAAALPWRSLSRIP-KREGLGEEDTAVAG----HELLLPNERSFQNAAKSNNLDLMEKLFEKKVNINVVNNMNRTALHFAVGRNHLSAVDFLLKHKARVDVADKHGLTVIHLAAWSGSLEVMLMLVKAGADQRAKNQDGMSALHFATQSNHVRIVEYLIQDLHLKDLNQPDEKGRKPFLLAAERGHVEMIEKLT--FLNLHTSEKDKGGNTALHLAAKHGHSPAVQVLLAQWQDINEMNELNISSLQIAT------------------------RN---------GHASLVNFLLSENVDLHQKVEPKESPLHLVVINNHITVVNSLLSAQHDIDILNQKQQTPLHVAADRGNVELVETLLKAGCDLKAVDKQGKTALAVASRSNHSLVVGMLIKAERYYAWRE----EHHESIRDPSTGFTLTFKQDHSLETRHIRTLLWDLAYHQLKANEWQRLARSWNFTDDQIRAIEEQWSGNESFREHGHRALLIWLHGTLMTQGDPAKQLYEELVHAGFPKLAEKTRHFKSKTDSNSKKCVVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZ15-1", "uniprot_id": "A0A8M9PZ15_DANRE", "id": "A0A8M9PZ15-1", "name": "", "aln": "MQTKPGVFYSTRASKAKSLSKQYSTVYSTMEKKAHALKDYILKQPVWMKENLNPKTWIKTDHSKGFAEFILPKDIGADGGYDNKEMLLETEKDFIEAAKRNNVEGMK-LLGRGVNVNAKNVHGRTALHYAVACRNVEAVDVLLRRRAKLDLQDKHGLTAVHLAAWFGSLEILKLLVQGGADQSIENTEGLNMLHCAAMNNHTDIVAYIIDDLQMGELDKEDQFGNRPFVLAAAHGCVPMLQMLMEEHYNMATMQENQVGDTPLHLAAKHGQREALQLLLENFHIRNEVNQAGQTALYLAADGAHEDCVQTLLEAQCDPNIFTLSRNSPLHPVCERGHFQIVQLLINSGAQINAQNQQMQTSFHLAVRNCHIPVIHTLLEAGCDPNLTDHMGQTALHIAAEMGKVDVVEMILKAGVDLQIRDRQNKTALGVAARGNMVIIVDMIIKAERYFKWKDNLQITNTDAIESLHSESPLTFKLDHSPDTKPVRDIMWDLAYKHLKRNDWKKLAEHWEFTDAQMAAIEEQWTGLNSFQEHGNRMLLIWLHGVLIEESSPSKGLYEGLLASGNSKVAGRMLLHISVVFRVCSDLCL-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. . . . ::.*: : . . .* . : * : : .. * :* ** *:.* :*** .*:: *: *: : **:*. * .*****:**. . :.***.** ::*::*: ******.:***** **:*:: :**:.**** :. :*:. ** *: .*: ** *:*.**:: :*:: :: *.:** *** :* * *:: * . *: * :::: *:*.***** **: .:*:** :: ** *: . ::* *: ** ** :*::*:....: : : : :..:**.* * : .*:.:**.* * : :: **.**:**: *:*::** :**** :*: *:*.****.**:*.: ::*.*:******: *:: : : *.. .**** *** :*: :* ::*:***::** ::*::**. *.**: *: ******:* :**:*** * *******.*: : .*:* *** *: :* .::* : . * . ... : ", "identical_positions": 196, "similar_positions": 181, "identity": "33.28%" }, { "cls_id": "homologset.agr.MGI:2444734", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y545-1", "uniprot_id": "A0A8I5Y545_RAT", "id": "A0A8I5Y545-1", "name": "Zinc finger protein 385B", "aln": "MNMASFLRGFEEKGLKNDRPGDQFSKEKKKILFSFCDVCNIQLNSAAQAQVHYDGKSHRKRVKQLSDGQPPPPAQGSVPLLASPCPGPGPGPGTNTSTGSACHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNTKRRGLFGTNKFFQMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYTGSKHAKKVKALEATKNKPKMVPSKDS-------------AKANPSCSVRPGTGDSSDKSED------KGKIKATSSSQPSGSEGGSFFLKSG---TTPLTLGAIASPS------KSTNG------APG-SVAESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKVQNG--SKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDLMKPLAPTFLSSPLAAAA-VSTALSLPPRPSASLFQAAAIPPALLRPGHGPIRATPTSILFAPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BXJ8-1", "uniprot_id": "Z385B_MOUSE", "id": "Q8BXJ8-1", "name": "Zinc finger protein 385B", "aln": "MNMATFLRGFEEKGLKNDRPGDQFSKEKKKILFSFCEVCNIQLNSAAQAQVHYDGKSHRKRVKQLSDGQPPPPVQGSVPLLAGPCPCPGPGP--NTSTGSACHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNT-------------MDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALEATKNKPKMVPSKDS-------------AKANPSCSIRPGTGDSSDKSED------KGKIKATSSSQPSGSEGGSFLLKSG---TTPLPLGAIASPS------KSTNG------APG-SVAESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKVQNG--SKGSGLQNKMFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDLMKPLAPTFLSSPLAAAA-VSSALSLPPRPSASLFQAAAIPPALLRPGHGPIRATPASILFAPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q569K4-1", "uniprot_id": "Z385B_HUMAN", "id": "Q569K4-1", "name": "Zinc finger protein 385B", "aln": "MNMANFLRGFEEKGIKNDRPEDQLSKEKKKILFSFCEVCNIQLNSAAQAQVHSNGKSHRKRVKQLSDGQPPPPAQ------ASPSS--------NSSTGSTCHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNT-------------MDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALDATKNKPKMVPSKDS-------------AKANPSCSITPITGNNSDKSED------KGKLKASSSSQPSSSESGSFLLKSG---TTPLPPGAATSPS------KSTNG------APG-TVVESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQNG--SKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDMMKPLAPAFLSSPLAAAAAVSSALSLPPRPSASLFQAPAIPPALLRPGHGPIRATPASILFAPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PBT9-1", "uniprot_id": "Z385B_DANRE", "id": "Q6PBT9-1", "name": "Zinc finger protein 385B", "aln": "---------------------MQLQQEKKKLLYSLCDVCNIQLHSAAQAQVHYNGKSHLKRVKQLNNGEVPKASASLAPTSLQSLSS-------SSSQGSSCHSNTLPTLVRTPSLMMQSGLDMKPFMTFPVESSSPVGLFPNFNT-------------MDPVQKAVINHTFGVSIPPKKKQVISCNICQLRFNSDSQAEAHYKGSKHAKKLKAQESPKNKQKSAVAQDSGTKTITSTSTNTTTTTTTTSSCTAVTASCSDQTEKSTEPLAAHKVPASPQAFVPAPVAPAVALVPSPCKTAPVHASPPTEPTGLAVALKNTSKPAALPTAPSEPSVESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMLEARNGAGPIKAYPRPGSKLKVQATQLNKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPTKPKYSPYNKQQRSSSSLAAKLALQNDLVKPISPAFLPSPFSTTT--VPSISLHPRPNTSIFQTASLPHSFLRAAPGPIRPTTGSILFAPY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.:****:*:*:*:******:******** :**** ******.:*: * . . . .:* **:**:.***:*****:****..**:****:***:***.********* ****************************:***************.*******:** ::.*** * . ::** :.:..:.* . *.. **::*. *: *:..: ... . :. * .. *:*: .. :.*: *.*. **. . .**************************************:**********:******:**:* .******** ********************************* ********* ***.* ******:*:*::**::*:**.**::::: .::** ***.:*:**:.::* ::**.. ****.*. *******", "identical_positions": 294, "similar_positions": 110, "identity": "54.95%" }, { "cls_id": "homologset.agr.MGI:2444736", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L177-1", "uniprot_id": "A0ABK0L177_RAT", "id": "A0ABK0L177-1", "name": "Leishmanolysin-like peptidase", "aln": "MPANGEAAEGPPPVRGKGGRQRGGVALHGNDAGPKMAAAGSGVAGGPGPGP---RGRWGGCLWVRGVLLVLGGLPAGAAAAPVSLGTSPPCRHHVL-SDTEVINKVHLKTSHVTKRDADGHLRIKTIYDQSIEELLPEKRYLVKNKLFPQAISYLEKTFQVRRPAGRILLSRQCATNQYLRKENDPHRYCTGECAVHTKCGPVIVPEEHLQQCRVCREGKWPCGAVG-VLDPEGVQDADFVLYVGALATERCSHENIISYAAYCQQEAKMDRPIAGYANLCPNMISTQPQEFIGMLSTVKHEIIHALGFSAGLFAFYHDQDGNPLTSRSAD-GLPPFNYSLGLYQWSDKVVRKVERL-WNVRDNKIVRHTVYLLVTPRVVEEARKHFNCPVLEGMELENQGGMGTELNHWEKRLLENEAMTGSHTQNRVLSRITLALMEDTGWYKANYSMAEKLDWGRGMGCEFVRKSCKFWIDQHRQKRQVPSPYCDTLRSNPLQLTCRQDQRAVAVCNLQRFPNPLPPEYQYFDELSGISAEDLPYYGGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPELFKNYGAEQYGPHSVCLLQKSAFVMEQ-CERKLSYPDWGSGCYQVSCSPQGLKVWVQDTSYLCSRAGQVLPVRIQMNGWIHNGNLLCPSCWDFC--------EQCPPETDPPAANLTRALPLVSCGWPNPQLHLQLRPSVNCPVPPSPLSLFAYLSVCNRDDVLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMN4-1", "uniprot_id": "LMLN_MOUSE", "id": "Q8BMN4-1", "name": "Leishmanolysin-like peptidase", "aln": "-----------------------------------MAAAGSGGAGGPGPGP---RGRWGGCLWVRGVLLVLGGLPAGAGAAPVSLGTSPPCRHHVL-SDTEVINKVHLKTNHVTKRDADGHLRIKTIYDQSIEELLPEKRYLVKNKLFPQAISYLEKTFQVRRPAGRILLSRQCATNQYLRKENDPHRYCTGECAVHTKCGPVIVPEEHLQQCRVCREGKWPCGAVG-VLDPEGVRDADFVLYVGALATERCSHENIISYAAYCQQEAKMDRPIAGYANLCPNMISTQPQEFIGMLSTVKHEIIHALGFSAGLFAFYHDQDGNPLTSRSAD-GLPPFNYSLGLYQWSDKVVRKVERL-WNVRDNKIVRHTVYLLVTPRVVEEARKHFNCPVLEGMELENQGGMGTELNHWEKRLLENEAMTGSHTQNRVLSRITLALMEDTGWYKANYSMAEKLDWGRGLGCEFVRKSCKFWIDQHRQRRQVPSPYCDTLRSNPLQLTCRQDQRAVAVCNLQRFPNPLPPEYQYFDELTGIPAEDLPYYGGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPELFKNYGAEQYGPHSVCLLQKSAFIMEQ-CERKLSYPDWGSGCYQVSCSPQGLKVWVQDTSYLCSRAGQVLPVRIQMNGWIHNGNLLCPSCWDFC--------EQCPPETDPPAANLTRALPLDLCSCSSS-LVVTLWLLLGNLFP-----LLAGFLLCVWH----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KR4-1", "uniprot_id": "LMLN_HUMAN", "id": "Q96KR4-1", "name": "Leishmanolysin-like peptidase", "aln": "-----------------------------------MAAEWGGGVGYSGSGPGRSRWRWSGSVWVRSVLLLLGGLRASATSTPVSLGSSPPCRHHVP-SDTEVINKVHLKANHVVKRDVDEHLRIKTVYDKSVEELLPEKKNLVKNKLFPQAISYLEKTFQVRRPAGTILLSRQCATNQYLRKENDPHRYCTGECAAHTKCGPVIVPEEHLQQCRVYRGGKWPHGAVG-VPDQEGISDADFVLYVGALATERCSHENIISYAAYCQQEANMDRPIAGYANLCPNMISTQPQEFVGMLSTVKHEVIHALGFSAGLFAFYHDKDGNPLTSRFAD-GLPPFNYSLGLYQWSDKVVRKVERL-WDVRDNKIVRHTVYLLVTPRVVEEARKHFDCPVLEGMELENQGGVGTELNHWEKRLLENEAMTGSHTQNRVLSRITLALMEDTG-------------------------------------RQMLSPYCDTLRSNPLQLTCRQDQRAVAVCNLQKFPKPLPQEYQYFDELSGIPAEDLPYYGGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPEIFKNYGAEKYGPHSVCLIQKSAFVMEK-CERKLSYPDWGSGCYQVSCSPQGLKVWVQDTSYLCSRAGQVLPVSIQMNGWIHDGNLLCPSCWDFC--------ELCPPETDPPATNLTRALPLDLCSCSSS-LVVTLWLLLGNLFP-----LLAGFLLCIWH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q5N1-1", "uniprot_id": "F1Q5N1_DANRE", "id": "F1Q5N1-1", "name": "Leishmanolysin-like peptidase", "aln": "-----------------------------------MMASG-------WRQP---RSVIGAALFFNTTIIIF--ISTGAQTH--------TCDHKVP-LHTEVIHKVFLKPDRLTKRSTDQQLNIKIEYDSSLDGLDEAKSSLVKDKLLPQAIDYLQKAFRVRRQSGPILLSRQCATNQYLRKRDDPHRYCQGPCANVTKCGPVVVPEHHLQQCRVCSESGKSCGPVG-PPDGEGVARADFVLYVSAMTTERCGQENIVAYAAYCQLESELDRPIAGYANLCPNMISTQPQEFEGMLSTVKHEIIHALGFSAGLFAFYHDDGGKPLTPRSAS-GLPAYNESLGLYQWSDKVIKRATRL-WDIRGGQMVRHTVHLLATPRVVEEARRHFNCPILEGMELENQGGAGTELNHWEKRLLENEAMTGSHTQNRVFSRITLAIMEDTGWYRANYSMAENLQWGRGLGCDFVMKSCKFWIDQHRHKRPTLSPYCDSVRSAPLQLTCRQDQLAVAVCNLQKFSNALPAEYQYFDHIPGVPKEDLSAYGGAVEIADYCPFSQEFSWHVGGEYQRSSYCRIQENQPATWRNYGAEQYGPGSVCLYQKSAFVMEQ-CTKRMTYPDWGSGCYKVSCTAQGLLVWVQNETFLCVRTGQVISVSIRMNEWVYNGQLICPACSDFC--------SNCPLPHLIPPLNTTKSAPIDPCSRSSF-LVVNLWQLLLTLTP-----LLIGFLLCGWD----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VH19-1", "uniprot_id": "LMLN_DROME", "id": "Q9VH19-1", "name": "Leishmanolysin-like peptidase", "aln": "-----------------------------------MAKTP-------PLRPHGNMAKFLAALGICSWLLVSATAHNCQHQHPKAHEVVHGVRIQLADSEDDSAGDPARHSVRRRSVAAEQPLRILLVYDESVYRLEEEKFNLINDTVLPEAVQFWEQALMVRETKGVIRLNRKCDSTQVYVKNG--HTHCIDHCKATTMCGEVQVPDAHLDVCRVCNATGQNCRIDSNTQPGEGIENADFVFYVSARQTQRCFKGLTVAYAAHCQQEAALDRPIAGHANLCPESISTKPQELQTLISTVKHEILHALGFSVSLYAFFRDDDGKPRTPRKLDTGKPYLNEKLQIHQWSNETIRKVVRENWSVRGG-HVNKVVDMMVTPRVIAEVRAHFNCNKLEGAELEDQGGEGTALTHWEKRILENEAMTGTHTQSPVFSRITLALMEDSGWYRANYSMATPLTWGKGLGCAFAMRSCKDWIQYNHARGRSIHPFCSKVKQDPLQTECTDDRNSVALCNLIRHEFELPKGYQNFDSLNHVKDGEEGFYGGSVSLADHCPYIQEFTWRSKNVIVRGSHCRFTENNPRPEKNFALESYGEGAKCFDHSESMWEERSCHQTREWQHWGSGCYKYDCFDGRLHILVGNYSYKCSFPGQKLSIRIAANGWLHKGAIMCPPCHELCGAQFAAQGKQCRPGEEPDPLNKYPRDNLACGAGSEKSRSVAIITAVLLLFG-----LRWGFS---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ..: . ::: :: . : . :. : . .: *.* **.*: * * *:::.::*:*:.: :::: **. * * *.*:* :.* *.. * :* . * * ** * **: **: *** . **: ****:**.* *:** : ::***:** *: :******:*****: ***:***: ::******::******..*:**::*..*:* *.* . * * * .* ::***::.:::. * *.:*.. *.:.* ::.****: *.* **:* *** ***:*** ** *.*****:********:***. *:******:***:* *:*..::. *** * :*: :**:*** :. ** ** ** : : : ***:*.:**:**: ***:*: . *.* **: **:* :*:. *.** : *: :..:: *: * : : .******: .* * : * : :: * .** :.: * * *::.* ::**.* ::* . * . * : . .. : : : * : ", "identical_positions": 217, "similar_positions": 175, "identity": "29.25%" }, { "cls_id": "homologset.agr.MGI:2444737", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZR4-1", "uniprot_id": "D3ZZR4_RAT", "id": "D3ZZR4-1", "name": "Protein fem-1 homolog C", "aln": "MDLKTAVFNAARDGKLRLLTKLLASKSKAEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDR----AKGLLGTTVTFDDLMGILCKSVLEIER-------------------------------------------AIKQTQCPADP--LQLNKALSIILHLICLLEKVP----CTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPD-IMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGNIPEKLETFVSLHR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CEF1-1", "uniprot_id": "FEM1C_MOUSE", "id": "Q8CEF1-1", "name": "Protein fem-1 homolog C", "aln": "MDLKTAVFNAARDGKLRLLTKLLASKSKAEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDR----AKGLLGTTVTFDDLMGILCKSVLEIER-------------------------------------------AIKQTQCPADP--LQLNKALSIILHLICLLEKVP----CTVEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPD-IMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGNIPEKLETFVSLHR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JP0-1", "uniprot_id": "FEM1C_HUMAN", "id": "Q96JP0-1", "name": "Protein fem-1 homolog C", "aln": "MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDR----AKGLLGTTVTFDDLMGILCKSVLEIER-------------------------------------------AIKQTQCPADP--LQLNKALSIILHLICLLEKVP----CTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPD-IMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7T3P8-1", "uniprot_id": "FEM1C_DANRE", "id": "Q7T3P8-1", "name": "Protein fem-1 homolog C", "aln": "MDLKTAVFNAARDGKLKLLQKLLENKSDREVLKLMAEKTNGATPLLMASRYGHLELVEFLMECCCAPVELGGSVNFDGEVIEGAPPLWAASAAGHLKVVQSLLGHGASVNNTTLTNSTPLRAACFDGHLDIVRYLVEHQADLEVANRHGHTCLMISCYKGHREIAQFLLEKGADVNRRSVKGNTALHDCAESGSLEIMKMLLKFGASMEKDGYGMTPLLSASVTGHTNIVDFLTAHPQTGLAERISALELLGATFVDKKRDLLGALQYWKRAMELRHSEAD-CMRREEPLEPEPAYDCSREVSTAEELDGLIADPDDMRMQALLIRERILGPAHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQSNLEPLSPMTASSLLSFAELFSFMLQDR----AKGLLGAGVSFQQLMEILCRSVLEIER-------------------------------------------AVKQPRPSPDPDPAQLSKLLSIILHLICLLEKLP----CSPEQDQHKKETIYRFLKLQACGRNGFSPLHLAVDHNTTCVGRYPVCKFPSLQVASVLLECGADVNSRDLDDNSPLHVAASNNHPD-IMKLLISGGTHFDSTNALQQTACDLLDHTQLAKSLIQPINHTTLQCLAARAIIRHRLVYRGSIPERLEAFVLLHR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFD5-1", "uniprot_id": "FEM1A_DROME", "id": "Q9VFD5-1", "name": "Protein fem-1 homolog CG6966", "aln": "MDYKFIVFNAARDNNLAQLKATLYNKSSVEVGSLISAKVNGATPLVISCRNGHYDIVEYLLTKCRANVEQVGSVSFDGEPIEDAPPLWCAAAAGHLGIVKMLVRRGANVNSTTRTNSTPLRAACFDGHYEIVKYLVHHGADFEVANRHGHTCLMIACYKGHFRIAQYLLSLNADVNRCSVKGNTALHDCAESGSLQILQLLLKHGATMDVDYYGMTPLLAASVTGHMPIVEHLITLPCVSRESRIHALELLGATYVDRKRDMAAALNLWRRALEERAVEPP---LEKKVQEPVPAYEMVREVTSVEELEEMVLDPDEMRMQALVIRQRILGPTHPDTSYYIRFRGAHYADAGRFDRCIELWSYALTMQQKILQPLSPMTQSSLLSFAELFSFMLVEAGRLLPRGRVVPPIEPDSMLTIFYKAVKEVERGLAFTLEQQKDQQHPQKQLPAADKSPSCSASSSASSSSSTTLLSAHQHDCNHDP--NALSRTMISAIHIGCLLSSLLDTDALSPEMRRQVMGALYRLNRLKVRVRFDRTALHYACYREGTLAGRYPSCQFPSVTLAKALLEVGADPNAIDEAGNTPLHLATMQPYVEPLSHILLEGGAHLDTKNYAGETFESLLAPTPMHK-IIDPMKYTTLACLAARTIKKHDIRYEGTVPATLYEFIELH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *******.:* * * .**. ** .*:: *.******:::.* ** ::**:*: * * :* ***.**** **.*****.*:***** :*: *: :**.**.** ************** :**:***.* **:**:**********:***** .***:**. .***** *****************:*:::** . *.*: * *******:****** **:.* . .. .** ********:**:***: .**: *::*:: * : . **: :**.:.***: :: ***:******:**:*****:*********:*** ***:*.*.***.**.*** ***. *:****** ************** : .:* : . : :.:: *: ::* *:** : :* ** *.: : :*: ***..: : * : ::**: :*: : . :.** * :: * .**** *:***: :: *:* *** * * .*:***:*: : : : : ::*:..*:*:*:.* :* .** . : * :*:*:::*** *****.* .* : *.* :* * *: ** ", "identical_positions": 312, "similar_positions": 157, "identity": "46.5%" }, { "cls_id": "homologset.agr.MGI:2444738", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CDN8-1", "uniprot_id": "CCD38_MOUSE", "id": "Q8CDN8-1", "name": "Coiled-coil domain-containing protein 38", "aln": "-------------------------------------------------------------------------------------MASQMHTSISSGDEGKDAVLKKERPYKIFFKDLFVFKENEIAARKKERMKNHSMKIYQKTTFSSRMKSRSHLGQLAFFADAGSSSYERLGLDPTLILRLTEGADRKRTVHEFINDQRDRFLLEYTVSTKKKTIKRFERLIAIKENQLKKAEKKLQDDALSFEEFLRENDQRSVDALKMAAQETINKLQMTSELKKASMEVQSIKSDIAKTEFLLKEYMKYGFFLLKLSPKQWQIQQSQKRAQSSKS--NHILPKILEKFSINTAKGDNSIDSD--KMSVSEEWSSRRGSQGGRHGKHTLGQDSRKSSGFTRPESMASEDSLEYFLEDELVEFDLLPEIYFKEPEELLQVFTELEEQNLTLVQYSQDVDENLEDVNKREKFIQDKINNNISFLLEHKHMLRMNCEREEEKAAELELRSRLFSFGEFNSDAQEKLIDSLSKKINQVYRVCIGDAEVGSLNAVQKLVKVESRLVELSDLIESIPREHVEAIERLKQKERRQKLREEKMKEKQRHQEERLKAALERAVAQPKKKLGRRLIYRSKPQSADKQELLLVSDTRSKSQDEEYFFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LUB9-1", "uniprot_id": "F1LUB9_RAT", "id": "F1LUB9-1", "name": "", "aln": "MASQLHVSRSSAEPGGRTPSQVHSARSSAEPGGRIPSQVHSARSSAEPGARITYQLHSSRSSAEPGARITSQLHTSRSSAEPGGRISSQLQTSRSSGDEAKDAELKKERPYKIFFKDLFLFKENEIAARKRERMKTHSMHIYQKTTFSSRMKSRSHLGQLAFFAEAGSSSYEKLGLDPTLILRLTEGADRKRTVHEFINDQRDRFLLEYAVSTKKNTIKRFERLIATKESQLKKAEKKLQDDALSFEEFLRENDQRSVDALKMAAQETINKLQMTSELKKAVMEVQAIKSEIAKTEFLLKEYMKYGFFLLKLSPKQWQVQQSQKRVQSSKS--NQVLPKILEKFSICTSKRNNSTDSD--RLSFSEDRSSKRGSLGGRRRKSTLGQDSRRSSVLARPESIASEDSLEYFIEDEIVEFDLMPEIYFKEPEELLQVLTELEEQNLTLVQYSQDVDENLEDVNKRERFIQDKINNNISFLLEHKNMLKVSCEREEEKAAELELRSRLFNFGEFNSDAQEKLIDSLSKKINQVYRVCIGDAEVGSLNAIQKLVKVESRLVELSDLIESIPKENVEAIERIKQKERRQKLREEKMREKQRHQEERLKAALERAVAQPKKKLGRRLIYRSRPHSANKHELLLIGDPRSKSQEEEYFFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q502W7-1", "uniprot_id": "CCD38_HUMAN", "id": "Q502W7-1", "name": "Coiled-coil domain-containing protein 38", "aln": "-------------------------------------------------------------------------------------MSSNLLPTLNSGGKVKDGSTKEDRPYKIFFRDLFLVKENEMAAKETEKFMNRNMKVYQKTTFSSRMKSHSYLSQLAFYPKRSGRSFEKFGPGPAPIPRLIEGSDTKRTVHEFINDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSN---LAESFGSEDSLEFLLDDEM-DVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVNETKTKSQEEEYFFT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*:: .: .**.: **. *::*******:***:.****:**:: *:: .:.*::************:*:*.****:.. .. *:*::* .*: * ** **:* *******************::***::***:**: ** :* **************:******************************:***** ****::**:********:**********::***:**:**: **.*:*** * :***** *:*: ::: :. :.. .**: *. *.* * . * :.::*. .**:.******::::**: :.** * :***********: *********.***********:*****:.**** *.**.****:::**: .* *********:*:*:**.********** *********.***:******* ..**.:*************.*******:*:******:**** ***:*:***:******:********:*************:::*:* *.:*::* *:.:.::***:*****:", "identical_positions": 370, "similar_positions": 138, "identity": "56.75%" }, { "cls_id": "homologset.agr.MGI:2444741", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHP7-1", "uniprot_id": "OLM2A_MOUSE", "id": "Q8BHP7-1", "name": "Olfactomedin-like protein 2A", "aln": "MEAAAVLPRYLQLRLLLVLLLLVLLRAGPVWPDSKVFSDLDQVRMTSEGSDCRCKCIMRPLSKDACSRVRSGRARVEDFYTVETVSSGADCRCSCTAPPSSLNPCENEWKMEKLKKQAPELLKLQSMVDLLEGALYSMDLMKVHAYIQKVASQMNTLEESIKANLSLENKVVKDSVHHLSEQLKSYENQSAIMMSIKKELSSLGLQLLQRDAAAVPATAPASSPDSKAQDTAGGQGRDLNKYGSIQKSFSDKGLAKPPKEKLLKVEKLRKESIKGRIP-QPTARPRALAQQQAVIRGFTYYKAGRQEARQEARQEAPKAAADSTLKGTSWLEKLPPKIEAKLP--EPNSAKHDDVRLQASEGGNLTPDITTTTTSTSSSTTTTTGTTSTTSTTSTTSTTTPSPITTPWPTEPPLHPEVPSQGREDSCEGTLRAVDPPVKHHSYGRHEGAWMKDPAALDDRIYVTNYYYGNSLVEFRNLENFKQGRWSNMYKLPYNWIGTGHVVYQGAFYYNRAFTKNIIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPAVDEHDETQHEVIVLSRLDPADLSVHRETTWKTRLRRNSYGNCFLVCGILYTVDTYNQHEGQVAYAFDTHTGTDAHPQLPFLNEYSYTTQVDYNPKERVLYAWDNGHQLTYTLHFVV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZMR0-1", "uniprot_id": "D3ZMR0_RAT", "id": "D3ZMR0-1", "name": "", "aln": "MEAAAVLPRCLQLRLLLVLLLLVLLRAGPVWPDSKVFSDLDQVRMTSEGSDCRCKCIMRPLSKDACSRVRSGRARVEDFYTVETLSSGADCRCSCTAPPSSLNPCENEWKMEKLKKQAPELLKLQSMVDLLEGALYSMDLMKVHAYIQKVASQMNTLEESIKTNLSLENEVVKDSVRHLSEQLKSYENQSAIMMSIKKELSNLGLQLLQRDAAAIPASAPASSSDNKAQDTAGGQGKELNKYGGIQKSFSDKSLAKPPKEKLLKVEKLKKETIKGRIPPHPTARPRALAQQQAVIRGFTYYKAG----RQEARQEAPKAAADNTLKGASWLEKLPPKTEAKLP--EPNSAKHDDIRLQASEGANLAPDFSTTTTTTTTTTTTTT-------------TTTPTPITTPWPTEPPLHPEVPSQGREDSCEGTLRAVDPPVKHHSYGRHEGAWMKDPAAPDDRIYVTNYYYGNSLVEFRNLENFKQGRWSNMYKLPYNWIGTGHVVYQGAFYYNRAFTKNIIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPAMDEHGETQHEVIVVSRLDPADLSVHRETTWKTRLRRNSYGNCFLVCGILYTVDTYNQHEGQVAYAFDTHTGTDAYPQLPFLNEYSYTTQVDYNPKERVLYAWDNGHQLTYTLHFVV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q68BL7-1", "uniprot_id": "OLM2A_HUMAN", "id": "Q68BL7-1", "name": "Olfactomedin-like protein 2A", "aln": "MAAAALPP-----RPLLLLPLVLLLSGRPTRADSKVFGDLDQVRMTSEGSDCRCKCIMRPLSKDACSRVRSGRARVEDFYTVETVSSGTDCRCSCTAPPSSLNPCENEWKMEKLKKQAPELLKLQSMVDLLEGTLYSMDLMKVHAYVHKVASQMNTLEESIKANLSRENEVVKDSVRHLSEQLRHYENHSAIMLGIKKELSRLGLQLLQKDAAAAPAT-PATGTGSKAQDTARGKGKDISKYGSVQKSFADRGLPKPPKEKLLQVEKLRKESGKGSFL-QPTAKPRALAQQQAVIRGFTYYKAG--------KQEVTEAVADNTLQGTSWLEQLPPKVEGRSNSAEPNSAEQDEAEPRSSERVDLASGTPTSIPATTTTAT-----------------TTPTPTTSLLPTEPPSGPEVSSQGREASCEGTLRAVDPPVRHHSYGRHEGAWMKDPAARDDRIYVTNYYYGNSLVEFRNLENFKQGRWSNMYKLPYNWIGTGHVVYQGAFYYNRAFTKNIIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPAVDDRDEAQPEVIVLSRLDPGDLSVHRETTWKTRLRRNSYGNCFLVCGILYAVDTYNQQEGQVAYAFDTHTGTDARPQLPFLNEHAYTTQIDYNPKERVLYAWDNGHQLTYTLHFVV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0UXR7-1", "uniprot_id": "B0UXR7_DANRE", "id": "B0UXR7-1", "name": "", "aln": "MKKMWIYAS--------VLTYLLLLT-RDARSLSKIFGEPEPVKMISEGSDCRCKCVMRPLSIEACSRLRDGSLRVDDFYTVETVSSGSDCKCSCTAPPSSLNPCENEWRTEKLRKQAPELLKLHSMVDLLEGTLYSMDLMKVHAYMNKVVSQMNTLEETIKTNLTRENEFVRDSVVNLSNQLKRYENYSDIMVSIKKEISSLGLQLLQKDAAS----------DSKAQGTESKKSKEAIKP-PNKKPPAVKPPPKQPKEKPVKPKKEAPAKAAKPAKPDPTTKTKTSVHQTGVIRGITYYKAS----KSEDSESHSTGRAERENQAKTHTGHQAEDKKGSEL--VLETSEISSTVLPITTTTTLVAVTTTSTTLATTSEVPVMN-------------STQSTPGPVKPIGTGGKTHLHKAGKSPDCEGTLASVEMPEKHHSYGRNEGAWMKDPMAKDNKIYVTNYYYGNNLVEFRNLENFKQGRWSNLYKLPYNWIGTGHVVYNGAFYYNRAFTKNIIKYDLRMRYVAAWTQLHDAVYEDTTPWKWRGHSDIDFAVDESGLWVIYPALD-YDYSQHEVIVISKLDPSDLSIKKETTWRTGLKRNSYGNCFIVCGVLYAIDVYNQKEGEVLYAYDTHTNTEATPRLPFTNEYAFVTQVDYNPKDKVLYAWDNGHQLTYNIHFVGQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . :* ::** . . **:*.: : *:* **********:***** :****:*.* **:*******:***:**:*****************: ***:*********:********:************::**.********:**:**: **:.*:*** :**:**: *** * **:.****:* *******:***: ..***.* :.:: * :*. : : .* **** :: :* . .**::.:: .:* .****:*****. :. . . *: :. : : . . :. :::: .. : *.. .*: . :::: . :* :. . * . ..: . *:. .***** :*: * :******:******** * *::**********.*****************:***************:******************* *:**:*: * *.*******************************:* . :* ****:*:***.***:::****:* *:********:***:**::*.***:**:* **:****.*:* *:*** **:::.**:*****::*************.:*** ", "identical_positions": 365, "similar_positions": 154, "identity": "53.28%" }, { "cls_id": "homologset.agr.MGI:2444746", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GM32-1", "uniprot_id": "A0A8I6GM32_RAT", "id": "A0A8I6GM32-1", "name": "", "aln": "---------MMSSVSTESKLQQ--AVSLKGVDPETCMIVFKNHWAQVVLAILQVVKILEKHDPLKNIQA-----------------KYGSIPPDEASAVQNYVEHMLFLLIEEQA-KDAAMGPILEFVVCENIMEKLFLWSLRR-EFTDETKLEQLKMYEMLVTQSYQPLLHHKPILKPLMMLLSSCSGTAT----PAVEGKLVVLLNQLCSILAKDPSILELFFHTSEDQG----------------AANFLIFSLLIPFIHREGTVGQQARDALLFIMSLSAENSMVANHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPALVQFMNSLEFCNAVIQVAHPLIRTQLVSYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHQHEN-VHILDTLTSRINTP-FRLCVVSLALFRTLIGLHCEDVMLQLVLRYLVPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCASGITLTLGNQERDYILWSKCMHDGSGPEEQPLPETPCSPSSPPPPPQPAPAACIVEYGKALDISYLQYLWEAHTNILHCMRDCRVWSALYDGDSPD--PETFLQSLSEESRENSSHPEARLSQQCIRTSG----QTKDKSQS----ELEWDDSYDTGISSGADVGSPGPYDDVETPA-PPAPIDPPKHIQEMKKNAILLFKGSYIEESDFQDDVMVYRLCAEKDAEDTREPQ------------------------------------------GATTDPPAEAQPKAQPEAQSLPTSNGPLFSPNPEAESKP--GRESSDLCQNMFSEAKPESEPGVALDSDSELTVPTFEAEPQSDSPVASTEGEDFIAQYDQIIQELDSGTEGLTEQSVPASEPSLLTHADEGRTECKAEE--------EEEDDDFDSLMADTPAEEAAPSPFGVGEDTATFTSRHPTRTQGTPFTGPFLSVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPVALTKDPIQEISRPESDKTLTDGPPRVLQPFLGNRAQMTKAPPNLPLPVKNTMLAAALFPEFLKELAALAQEHSILCYKILGDLEDSCC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q505K2-1", "uniprot_id": "FHI1A_MOUSE", "id": "Q505K2-1", "name": "FHF complex subunit HOOK-interacting protein 1A", "aln": "---------MMSSVSTESKLQQ--AVSLKGVDPETCMIVFKNHWA-------QVVKILEKHDPLKNTQA-----------------KYGSIPPDEASAVQNYVEHMLFLLIEEQA-KDAAMGPILEFVVCENIMEKLFLWSLRR-EFTDETKLEQLKMYEMLVTQSYQPLLHHKPILKPLMMLLSSCSGTAT----PAVEGKLVVLLNQLCSILAKDPSILELFFHTSEDQG----------------AANFLIFSLLIPFIHREGTVGQQARDALLFIMSLSAENSMVANHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEDWHCILKDDWLLLPALVQFMNSLEFCNAVIQVAHPLIRTQLVSYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHRHEN-VHILDTLTSRINTP-FRLCVVSLALFRTLIGLHCEDVMLQLVLRYLVPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCASGITLTLGNQERDYILWSKCMHDGSGSEEQLLPETPCSPSSPSPPPPPAPAACIVEYGKALDISYLQYLWEAHTNILHCMRDCRVWSALYDGDSPD--PETFLQSLSEESRENSGHPEARLPQQSVRTSG----QTKDKSQS----ELEWDDSYDTGISSGADVGSPGPDDEVETPA-PPAPIDPPKHIQEMKKNAILLFKGSYIEESDFQDDVMVYRLCAEKDTEDTTEPQKDTSEPQGDTLEPLEDTSEQQEDTSEQLEDTSELQEDTAEPQGDTADPTAEAQPKLQPEAQSLPTSNGPLSSPDPETESQP--SRESSDLCQNTFSEAKPENEPGVALALDSELIATTFEAEPQSELAVVSTESEDFIAQYDQIIQELDSGTEGLTEQSIPISEPSLLTQQEERREECK-----------EEEDDDFDSLMAATPAVEAGSSPFGVGEDTA-FSSRHPVRTQSTPFTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMAPAALTKDPIQEISRPESDKTLLDGPPRVLQPFLGNRAKVTRAPPNLPLPVKNTMLAAALFPEFLKELAALAQEHSILCYKILGDFEDSCC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05DH4-1", "uniprot_id": "FHI1A_HUMAN", "id": "Q05DH4-1", "name": "FHF complex subunit HOOK-interacting protein 1A", "aln": "---------MMSSVSTESKLQQ--AVSLQGVDPETCMIVFKNHWA-------QVVKILEKHDPLKNTQA-----------------KYGSIPPDEASAVQNYVEHMLFLLIEEQA-KDAAMGPILEFVVSENIMEKLFLWSLRR-EFTDETKIEQLKMYEMLVTQSHQPLLHHKPILKPLMMLLSSCSGTTT----PTVEEKLVVLLNQLCSILAKDPSILELFFHTSEDQG----------------AANFLIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPSLVQFMNSLEFCNAVIQVAHPLIRNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHQHEN-VHILDTLTSRINTP-FRLCVVSLALFRTLIGLHCEDVMLQLVLRYLIPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCSSGITLTLGNQERDYILWSKCMHDTSGPVERPFPEAFS------------ESACIVEYGKALDISYLQYLWEAHTNILRCMRDCRVWSALYDGDSPD--PEMFLQSLTEEGSVSSACPVFGLPQQLPRKTGPQLAPRKDKSQT----ELEWDDSYDTGISSGADVGSPGPYDDLEVSG-PPAPIDPPKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQ------------------------------------------EEAARPPAEAQ----AEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPF-VGRDEAAFASRHPVRTQSTPFTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPAALTKDPIQEASRTGSGKNLLDGPPRVLQPFLTHRTKVAEAPPNLPLPVRNPMLAAALFPEFLKELAALAQEHSILCYKILGDFEDSCC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PRC5-1", "uniprot_id": "A0A8M9PRC5_DANRE", "id": "A0A8M9PRC5-1", "name": "", "aln": "---------MTSMVYNGNRGGQ--TLVLTGVDPETCMIVFKNHWA-------QVVKILEKHDPLRSNTGGLGGGHGLAGGGGLGSFRFGPIPGDEASAVQNYVEHMLFLLMEEECGQNGAMGPILEFVVMENVLERLFIWSLRR-EFTDDMKLEQLKMYEMLIGQARQPLLHHKPVLKPLMMLLSSCSGSPTGPSSPAVETELVLLLNQLCCVLAKDPSVLELFFHTSEDQG----------------AANFLIFSLLIPFIHREGSVGQQARDALLLIMALSAENHVVAKHIAENTYFCPVLATGLSGLYSSLPTKLDVPSEEWHCLHRDDWQQLPALVQFLNSLEFCNAVIQVAHPSIRDQLVGYIHNGFLVPVLAPALHKLTLEEVMTTTAYLDLFIRSVSEPALLHTFLSFILLHRHDS-VHILDTLVSRINTP-FQLGTVSLALFRTLIGLYCEDVMLQLIFKYLIPCNHMMLSQRRVLNERDCYSVSAAKILALTPSCCSPEIFPPP-LRQLDSILWSKGT-DGSQTGTMETKETLL-----------AEDDCVIGSEIYLDVSYLHYLYDARNSISHCMRACSVWSAPYNGENPP--PEEYQRSTLEEANRTRSSVATRKKTNSVHNSGP---PLKDLSATPGLLDLEWDDSYDA---CPAQVHTE---EDQETRH-IPD--EPPEHIQELRRTAIMFVKGSYIEESEFQNDVMVYNLVAQKDANDSGNNY---------------------------------------------RDPSKPTE----PEKQEVLDGR----TTDQKAKNSE-------SSINNGLNSPVNEMD--------------SKKRGLQSDHKLQGPEGEDLMAQYEELIRTLGAQPNSPTKADSELKSRVDLIDDEE-------------------DEMDFNSFSPETPEAEKLPSPFGTKPRSG-------SKGHAVPFTGPFVSVLLSRLENMPSNTLHVNLLLTGILAQLAAYPQPLLRSFLLNTNLVFQPSVRSLYQVLASVKNQIDVWSSKNKDSSELLTAAQHCLLARESS--------LRDPQSSQAEDASEADRIK------------RNSAIQPKTVVPLS-KTEVYATVLFAEFLKELAAIAQEHSILSHLPTEQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQK0-1", "uniprot_id": "U518_DROME", "id": "Q9VQK0-1", "name": "FHIP family protein CG3558", "aln": "MWLRQSSGGGVASVGHVGPLRQRPIDAATDCDPRACYDSFCKHWQ-------QAFEIIQHSAPPSHDDVLG----------------VVSHLDYMVTLLLVELHHCNKVSLPAAEASGPPAAPCLEFLLSENLLDKLYEWACTTGRYANAVRLEQLKLYELLVSHSRHQLLCHEPFLRPLLKILASSQGEIFP---PDLEKRLVILLNQLCVVLMQNVHLLDLFFFSAQTQVQEQILNGNVAPPKSGTTTNFIIFSLLIPYVHREGSLGHQARDALLLCMALSQKNSNIGTYIAQYSSICPLLVTGLGGLYSRLPNSIEISSIDWHRITPDDVTEIPELTLFMNALEFCNAVVQVAHEMIKQQLLDFMYQGFIVPVLGPAILQTNIDSQISAMSYLDLILRSITEPGLLRAFVRFLLDTEKFDGERILDALVERLNSPDANLCMVTMALFDTLLGLHCEDLMLELLLKFMLPGKHVPISHRHKINKIDPYLNSSEFFLELSPDVMKRARDLARPKSVHEPVVSELTPLPSLPSPVMSKTIGAN------------WNYYGVHTGDSLYANIQAYLFEAHWRIAQCQKDCLKWANSYRYQKWPRHGQGRVHAHALELARQFFSEFGGGPIAANETGEKQLDSLQSIGESSGYESFKWRPADEESEATDTTVATTASEADMDHNSSSLSSVLGASGKRESWRTSNSNRNELILTDLDFSEDLFAQGTVSLGPFLNAIWGK-------------------------------------------LQTFTSNSLYVNLHLTGLITRLAWYPLPLIHSLLLRSDIAITSDTPSFHQVLRILKQQID--------------AELPVTEDSLEIIDVARSSLIDREFRLANARKGNEGSPMHHSQQQQMVTNSGQQQG------------------QLRSAYATLSAATPVQATPTSAYDPFKRSD------NKRRSISKSITSMFSRKSASTSTAPPNGSSASSGLSQIYAFFTGAASNLVGNNASNDGRGISQAQTSAGTCETSLSTQPPAGASRTGANATSTAASGSNSSIAGSTLTLSAQSNTTTHSASTLHGLDGGPSTGGFNSEPASLDSVASMGIIASTSGTERSRDLALCAVLMDEWLKELAAIAQEQSVVLVTEQGSL-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . * . **.:* * :** *..:*::: * . .: : :.* : : .. . .* ***:: **::::*: *: .::: ::****:**:*: :: : ** *:*.*:**: :*:*..* * :* .**:****** :* :: :*:***.::: * ::**:*******::****::*:*******: *:** :* :. :*.: : :**:*.***.**** **..:: . :** : ** :* *. *:*:*******:**** *: **:.::::**:****.**: : .::. ::: :****::**::**.**. *: *:* .: . :***:*..*:*:* .* *::*** **:**:***:**:*::::::* :*: :*:* ::: * * *: :* *:* . : :: . . : * . **::*: * :* : * *: * :. : :: * .. :. . : .::* : : : * : : : .. :* :.: : : : :*.:*::. : : .. . . :. : : : ... ..:: : .: . . . . . . : : :: . * .*.: : .:.* : .. * .. * * : ::. .. *: . * . :. : * :*:..: :* . : . . . . . . . : .:.*: *:******:***:*:: . ", "identical_positions": 204, "similar_positions": 287, "identity": "17.51%" }, { "cls_id": "homologset.agr.MGI:2444748", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAP7-1", "uniprot_id": "D3ZAP7_RAT", "id": "D3ZAP7-1", "name": "ATP-dependent chromatin remodeler CHD7", "aln": "-------------------------------------------------------------MADPGMMSLFGE------------DGNIFSEGLEGLGECGYPENPVNPMGQQMPID-QGFPSLQPSLHHPSPNQ-NQTKL-THFDHYNQYEQ-KMHLMDQPN-RMMGSAPGNGLASPHSQYHTPPVPQVPHGGGSGGGQMGVYPGMQNDRHGQSFVDGGSMWGPRAVQVPDQIRAPYQQQQPQP-----APSGPPAQGHP----------------------------------------QHMQQMGSYLARGDFSMQQ-----PQQRMSQFSQG--QEGLSQGSPFIATSGPGGHLSHMPQQSPNI-------APSLRHPVQQQFHHHP--AALHGESVA-HSPRFSPNPPQQ--------GAVRPQTLNFSSRSQTVPSPTVNNSGQYSPYP-YRNLNQGLVNSTGMNQNLGLTNSTPMN--------------------------------QSVPRYPNAVG---FPSNSGQ-------GLMLQQPIHSSGSLNQMNTQTMHPSQ----------------PQGTYASPPPMSPMKAMSNPAGTPPPQ-VRPGSAGIPMDVGSYPNMPHPQPSHQPPGAMGIGQRNMGPRNIQQPRP-------------FMGMSSTPRELTGHMRPNGCPGVGLADAQAIQERLIPGQQHPGQQP-----PFQQ----------LPTCPPLQPHPGLHQ--------------SSPPHPHHQPWAQLHPSPQNTPQKVPVRQHSPSEPFLEKPVPDMTQVSGQNAQLVKSDDYLPSIEQQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQQKKKKKKNNHIAAGDPSKGFGKDDFPGGVDNQ----------------------------------------ELSRNSLDASQEETKKRKRPKVKKDPKELKEPREKKEPK--------------------------------------------------------------------------------------------------------------TPKAPKTPKEPKERKAKTVTPKPKSSKKSSNKKPDSEASALKKKVNKGKTEG-------SENSDLDKTPPPSPGPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEE-------------ADDADAAGRDSPSNTSQSEQQ------------------------------------------------------------ESVDAEGPVVEKIMSSRLVKKQKESGEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEVEEFYVKYKNFSYLHCQWASVEDLEK-DKRIQQKIKRFKSKQGQSK-FLSEIEDDLFNPDYVEVDRIMDFARSTDDR-GEPVTHYLVKWCSLPYEDSTWELRQDLDQAKIEEFEKL--MSREPETERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNMRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFLSK--------GGGQANVPNLLNTMMELRKCCNHPYLINGAEEKILEEFKDAHNADSPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTITIESEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAELDIDALNG--RNNLVIDTPRVRKQTRLYSAVKEDELMEFSDLESDSEEKPCIKPRRPQDKTQ--------------------------------GYARSECFRVEKNLLVYGWGRWTDILSHGRYKRQLTEHDVETICRAILVYCLNHYRGDENIKSFIWDLITPTADGQTRALLN-HSGLSAPVPRGRKGKKVKAQSMQPVVQDADWLASCN-----------------------------------------------PDALFQEDSYKKHLKHHCNKVLLRVRMLYYLRQEVIGDQAEKILEGADSSEADVWIPEPFHAEVPADWWDKEADKSLLIGVFKHGYEKYNSMRADPALCFLERVGMPDA-------------------------------------------------------------------------------------------------------------------------------------------------KAIAAEQRGTDMLADGGDGGEFDREDEDPE----------------------------------------------------------YKPTRAPFKDEIDEFANSPPEDKEDSMEAQS-TGKHSESNAELGQLYWPNTSSLTTRLRRLITAYQRSYKRQQMRQEALMKTDRRRR---------RPREEVRALEAER------------------------------------EAIISEKR-----------------------------------------------------------------------------------QKWTRREEADFYRVVSTFGVIFDP---------VKQQFDWNQFRAFARLDKKSDESLEKYFSCFVAMCRRVCRMPAKPEDEPPDLASLIEPITEERASRTLYRIELLRKIREQVLHHPQLSDRLKLCQPSLDLPEWWECGRHDRDLLVGAAKHGVSRTDYHILNDPELSFLDAHKSFAQNRGAST-----VPSLNTLAMG---------FGQAPPVIASAHAHEEK------VMEQAEGKAEECEHSPAKERSDGKE----EEEEAGG-AKDSRQECEAEASSVKGELKGVEGSGDPGSKS-----------------------VSEKGSEEDEEEKLEDDDKSEESSQPEAGAVSRGKTFDEESNASMSTAR---------------------------------------------------------------------------------------------------------DET---RDGFYMEDGDPSVAQLLH---------------------ERTFAFSFWPKDRVMINRLDNICEAVLKGKWPINRRQ------------------------MFDFQGLVPGYPPSTVDSPLQKRSFAELSMVSQASVSASEDITTSPQLSKDDALN------------------------------------------------------LSVPRQ------RRRRRRKVEIEAERAAKRRNLMEMVAQLRESQVVSENGQEK---------------------------------------------------------------VVDLSKASREATSSTSNFSSLTSKFILPNVSTPVSDAFKTQMELLQAG-LSRTPTRHVLNGSLVDGEPPMKRRRGRRKNVEGLDLLFMSHKRT---------------------------PLSAEDAEVTKAFEEDIETPPIRNIPSPGQLDPDTRIPVINLEDGTRLVGEEAPK--------------------------------------------------NKDLVDWLKLHPMYTVDMPSYVPK-----------------------------------------------NADVLFSPFQKPKQKRHRCRNPNKLDINTLTGEERVPVVNKRNGKKMGGAMAPPMKDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVRGEGASRRGRRPKSEIAR------AAAAAAAVASTSG----------------------------------------------------------INPLLVNSLFAGMDLTSLQNLQNLQSLQLAG-LMGFPPGLATAATAGGDAKGPAAVLPLMLPGMAGLPNVFGLGGLLNNPLSAATGNTTTASS--QGEPEDG------------------------------------------------------------------------------------------TSKAEEKGNDNEDENRDSEKSTDAVSAADS-----ANGSVGAATAPAALPSNPLAFNPFLLSTMAPGLFYPSMFLPPGLGGLTLPGFP--ALAGLQNAVG-----ASEEKAADKAE----------GGPCKDGE----TLEGSDAEENLDKTIESSILEDEVAQ-GEELDSLEGGDEIENNGNDE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AJK6-1", "uniprot_id": "CHD7_MOUSE", "id": "A2AJK6-1", "name": "ATP-dependent chromatin remodeler CHD7", "aln": "-------------------------------------------------------------MADPGMMSLFGE------------DGSLFSEGLEGLGECGYPENPVNPMGQQMPID-QGFPSLQPSLHHPSPNQ-NQTKL-THFDHYSQYEQ-KMHLMDQPN-RMMGSAPGNGLASPHSQYHTPPVPQVPHGGG-GGGQMGVYPGIQNERHGQSFVDGGSMWGPRAVQVPDQIRAPYQQQQPQP-----APSGPPAQGHP----------------------------------------QHMQQMGSYLARGDFSMQQH--GQPQQRMGQFSQG--QEGLSQGSPFIATSGPG-HLSHMPQQSPSM-------APSLRHPVQQQFHHHP--AALHGESVA-HSPRFSPNPPQQ--------GAVRPQTLNFSSRNQTVPSPTVNNSGQYSRYP-YSNLNQGLVNSTGMNQNLGLTNSTPMN--------------------------------QSVPRYPNAVG---FPSNSGQ-------GLVHQQPIHSSGSLNQMNTQTMHPSQ----------------PQGTYASPPPMSPMKAMSNPAGTPPPQ-VRPGSAGMPMEVGSYPNMPHPQPSHQPPGAMGIGQRNMGPRNMQQPRS-------------FMGMSSAPRELTGHMRPNGCPGVGLADPQAIQERLIPGQQHPGQQP-----SFQQ----------LPTCPPLQPHPGLHQ--------------SSPPHPHHQPWAQLHPSPQNTPQKVPVHQHSPSEPFLEKPVPDMTQVSAQNAQLVKSDDYLPSIEQQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQQKKKKKKNNHIAAGDSSKGFGKDDFPGGVENQ----------------------------------------ELRRNSLDVSQEEKKKKKRPKVKKDPKESKEPKEKKEPK--------------------------------------------------------------------------------------------------------------TPKAPKIPKEPKEKKAKTVTPKPKSSKKSSNKKPDSEASALKKKVNKGKTEG-------SENSDLDKTPPPSPAPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEE-------------ADDADAAGRDSPSNTSQSEQQ------------------------------------------------------------ESVDAEGPVVEKIMSSRLVKKQKESGEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEVEEFYVKYKNFSYLHCQWASVEDLEK-DKRIQQKIKRFKSKQGQSK-FLSEIEDDLFNPDYVEVDRIMDFARSTDDR-GEPVIHYLVKWCSLPYEDSTWELKQDIDQTKIEEFEKL--MSREPETERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNMRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFLSK--------GGGQANVPNLLNTMMELRKCCNHPYLINGAEEKILEEFKETHNAESPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTITIESEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAELDIDALNG--RNNLVIDTPRVRKQTRLYSAVKEDELMEFSDLESDSEEKPCAKPRRPQDKSQ--------------------------------GYARSECFRVEKNLLVYGWGRWTDILSHGRYKRQLTEQDVETICRAILVYCLNHYRGDENIKSFIWDLITPTADGQTRALLN-HSGLSAPVPRGRKGKKVKAQSTQPVVHDAHWLASCN-----------------------------------------------PDALFQEDSYKKHLKHHCNKVLLRVRMLYYLRQEVIGDQAEKILEGADSSEADVWIPEPFHAEVPTDWWDREADKSLLIGVFKHGYEKYNSMRADPALCFLERVGMPDA-------------------------------------------------------------------------------------------------------------------------------------------------KAIAAEQRGTDMLADGGDGGEFDREDEDPE----------------------------------------------------------YKPTRAPFKDEIDEFANSPAEDKEESMEVHS-SGKHSESNAELGQLYWPNTSTLTTRLRRLITAYQRSYKRQQMRQEALMKTDRRRR---------RPREEVRALEAER------------------------------------EAIISEKR-----------------------------------------------------------------------------------QKWTRREEADFYRVVSTFGVIFDP---------VKQQFDWNQFRAFARLDKKSDESLGKYFSCFVAMCRRVCRMPAKPEDEPPDLASLIEPITEERASRTLYRIELLRKIREQVLHHPQLSDRLKLCQPSLDLPEWWECGRHDRDLLVGAAKHGVSRTDYHILNDPELSFLDAHKSFAQNRGAST-----VPPLNTLAMG---------FGQTPPVISSAHVHEEK------AMEQAEGKAEECEHSPAKERSDGKE----EEEEAGG-AKDGKQECEVEASSVKGELKGVEGSADPGSKS-----------------------VSEKGSEEDEEEKLEDDDKSEESSQPEAGAVSRGKTFDEESNASLSTAR---------------------------------------------------------------------------------------------------------DET---RDGFYMEDGDASVAQLLH---------------------ERTFAFSFWPKDRVMINRLDNICEAVLKGKWPVNRRQ------------------------MFDFQGLVPGYPPSAVDSPLQKRSFAELSMVSQASISASEDITTSPQLSKDDALN------------------------------------------------------LSVPRQ------RRRRRRKVEIEAERAAKRRNLMEMVAQLRESQVVSENGQEK---------------------------------------------------------------VVDLSKASREATSSTSNFSSLTSKFILPNVSTPVSDAFKSQMELLQAG-LSRTPTRHMLNGSLVDGEPPMKRRRGRRKNVEGLDLLFMSHKRT---------------------------PLSAEDAEVTKAFEEDIETPPIRNIPSPGQLDPDTRIPVINLEDGTRLVGEDAPK--------------------------------------------------NKDLVDWLKLHPTYTVDMPSYVPK-----------------------------------------------NTDVLFSSFQKPKQKRHRCRNPNKLDINTLTGEERVPVVNKRNGKKMGGAMAPPMKDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVRGEGASRRGRRPKSEIAR------AAAAAAAVASTSG----------------------------------------------------------INPLLVNSLFAGMDLTSLQNLQNLQSLQLAG-LMGFPPGLATAATAGGDAKSPAAVLPLMLPGMAGLPNVFGLGGLLNNPLSAATGNTTTASS--QGEPEDG------------------------------------------------------------------------------------------TSKAEEKGNDNEDENRDSEKSTDTVSAADS-----ANGSVGAATAPAALPSNPLAFNPFLLSTMAPGLFYPSMFLPPGLGGLTLPGFP--ALAGLQNAVG-----TSEEKAADKAE----------GGPCKDGE----TLEGSDAEENLDKTVESSILEDEVAQ-GEELDSLEGGDEIENTGNDE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2D1-1", "uniprot_id": "CHD7_HUMAN", "id": "Q9P2D1-1", "name": "ATP-dependent chromatin remodeler CHD7", "aln": "-------------------------------------------------------------MADPGMMSLFGE------------DGNIFSEGLEGLGECGYPENPVNPMGQQMPID-QGFASLQPSLHHPSTNQ-NQTKL-THFDHYNQYEQQKMHLMDQPN-RMMSNTPGNGLASPHSQYHTPPVPQVPHGGS-GGGQMGVYPGMQNERHGQSFVDSSSMWGPRAVQVPDQIRAPYQQQQPQPQPPQPAPSGPPAQGHP----------------------------------------QHMQQMGSYMARGDFSMQQH--GQPQQRMSQFSQG--QEGLNQGNPFIATSGPG-HLSHVPQQSPSM-------APSLRHSVQQFHHHPS--TALHGESVA-HSPRFSPNPPQQ--------GAVRPQTLNFSSRSQTVPSPTINNSGQYSRYP-YSNLNQGLVNNTGMNQNLGLTNNTPMN--------------------------------QSVPRYPNAVG---FPSNSGQ-------GLMHQQPIHPSGSLNQMNTQTMHPSQ----------------PQGTYASPPPMSPMKAMSNPAGTPPPQ-VRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNMGPRNMQQSRP-------------FIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQP-----SFQQ----------LPTCPPLQPHPGLHHQ-------------SSPPHPHHQPWAQLHPSPQNTPQKVPVHQHSPSEPFLEKPVPDMTQVSGPNAQLVKSDDYLPSIEQQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQ----------------------------------------ELNRNSLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKE-----------------------------------------------------------------------------------------------------------PKTPKAPKIPKEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEG-------SENSDLDKTPPPSPPPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEE-------------ADDADAAGRDSPSNTSQSEQQ------------------------------------------------------------ESVDAEGPVVEKIMSSRSVKKQKESGEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VEIEEFYVKYKNFSYLHCQWASIEDLEK-DKRIQQKIKRFKAKQGQNK-FLSEIEDELFNPDYVEVDRIMDFARSTDDR-GEPVTHYLVKWCSLPYEDSTWERRQDIDQAKIEEFEKL--MSREPETERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNMRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFLSK--------GGGQANVPNLLNTMMELRKCCNHPYLINGAEEKILEEFKETHNAESPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTITIESEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAELDIDALNG--RNNLVIDTPRVRKQTRLYSAVKEDELMEFSDLESDSEEKPCAKPRRPQDKSQ--------------------------------GYARSECFRVEKNLLVYGWGRWTDILSHGRYKRQLTEQDVETICRTILVYCLNHYKGDENIKSFIWDLITPTADGQTRALVN-HSGLSAPVPRGRKGKKVKAQSTQPVVQDADWLASCN-----------------------------------------------PDALFQEDSYKKHLKHHCNKVLLRVRMLYYLRQEVIGDQADKILEGADSSEADVWIPEPFHAEVPADWWDKEADKSLLIGVFKHGYEKYNSMRADPALCFLERVGMPDA-------------------------------------------------------------------------------------------------------------------------------------------------KAIAAEQRGTDMLADGGDGGEFDREDEDPE----------------------------------------------------------YKPTRTPFKDEIDEFANSPSEDKEESMEIHA-TGKHSESNAELGQLYWPNTSTLTTRLRRLITAYQRSYKRQQMRQEALMKTDRRRR---------RPREEVRALEAER------------------------------------EAIISEKR-----------------------------------------------------------------------------------QKWTRREEADFYRVVSTFGVIFDP---------VKQQFDWNQFRAFARLDKKSDESLEKYFSCFVAMCRRVCRMPVKPDDEPPDLSSIIEPITEERASRTLYRIELLRKIREQVLHHPQLGERLKLCQPSLDLPEWWECGRHDRDLLVGAAKHGVSRTDYHILNDPELSFLDAHKNFAQNRGAGN-----TSSLNPLAVG---------FVQTPPVISSAHIQDER------VLEQAEGKVEEPENPAAKEKCEGKE----EEEETDGSGKESKQECEAEASSVKNELKGVEVGADTGSKS-----------------------ISEKGSEEDEEEKLEDDDKSEESSQPEAGAVSRGKNFDEESNASMSTAR---------------------------------------------------------------------------------------------------------DET---RDGFYMEDGDPSVAQLLH---------------------ERTFAFSFWPKDRVMINRLDNICEAVLKGKWPVNRRQ------------------------MFDFQGLIPGYTPTTVDSPLQKRSFAELSMVGQASISGSEDITTSPQLSKEDALN------------------------------------------------------LSVPRQ------RRRRRRKIEIEAERAAKRRNLMEMVAQLRESQVVSENGQEK---------------------------------------------------------------VVDLSKASREATSSTSNFSSLSSKFILPNVSTPVSDAFKTQMELLQAG-LSRTPTRHLLNGSLVDGEPPMKRRRGRRKNVEGLDLLFMSHKRT---------------------------SLSAEDAEVTKAFEEDIETPPTRNIPSPGQLDPDTRIPVINLEDGTRLVGEDAPK--------------------------------------------------NKDLVEWLKLHPTYTVDMPSYVPK-----------------------------------------------NADVLFSSFQKPKQKRHRCRNPNKLDINTLTGEERVPVVNKRNGKKMGGAMAPPMKDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVRGEGASRRGRRPKSEIAR------AAAAAAAVASTSG----------------------------------------------------------INPLLVNSLFAGMDLTSLQNLQNLQSLQLAG-LMGFPPGLATAATAGGDAKNPAAVLPLMLPGMAGLPNVFGLGGLLNNPLSAATGNTTTASS--QGEPEDS------------------------------------------------------------------------------------------TSKGEEKGNENEDENKDSEKSTDAVSAADS-----ANGSVGAATAPAGLPSNPLAFNPFLLSTMAPGLFYPSMFLPPGLGGLTLPGFP--ALAGLQNAVG-----SSEEKAADKAE----------GGPFKDGE----TLEGSDAEESLDKTAESSLLEDEIAQ-GEELDSLDGGDEIENNENDE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGL1-1", "uniprot_id": "F1QGL1_DANRE", "id": "F1QGL1-1", "name": "", "aln": "-------------------------------------------------------------MADPGMMSLFGD------------DGNLFSDELEGLGDCGYPQGQTNPMSQQMPHEHQGYGQLPPSLHLSSPAVPGQAKLGHHFDPFNQYEQPKMHPMDQQGGRMMGNGPVNGMSSPHSRYHG------AQAGAGGAAGHHVYPGAQGDGRSQSFPDSGNTWGAQPMQVPEQTRPPFQQQPPQA-----SSHQHGPAGPQ----------------------------------------GHAHQMGPFIGRGDYAIQGHNQTQTPPRMNHFPQGLPQEANHFLGHVGMTQNPG--MSGPPIRHLAQ-------PSQQHQQPNQQFLHRPGQGPVHPDSVASHNPQFPQSPSRQQQQQQQVMGGRPHQNMGFNMHNQQVPSNTVNSSGQYPPYSSYGNLNQGLANTSGMSPNLSLTTSSNSNPN---------------------------APVTQVQRYPAPAGPQRYPTPGGQQ------GPLHQQPIH----VNQINTQPMHPAQNQATAQPKLQQHLPPPPQGSYSSPPSMSPMRNLATPAGTPPPQQVRPPSAGLATDVGGYPGVPHQSQGPMAHAQRGAGPMNAAQPLPHQQLPSHSTHPHPPTTQMYAALSPNHRATAAQGRSSTTPGGNHTEPPGPQDQRLHAQQAQCQQLQKPPLPFQQQQLQQ--VHTPPSIPPSQTHLAAHHQ-------------SSPPS--QQAWAPTHQSPP-PMQKVPHMLHSPPDPSLEIITSSKTPAMGPNLQPANCD--LQQKESE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKPKKKKKKKAKVSEGQECNNISSE--AGGEVTA----------------------------------------LMNEGDSLITPVEKPAEKKSKKKPKEKEPKEPKEPKTPKT-----------------------------------------------------------------------------------------------------------PKTPKTPKEPKEPKEKKVKTATPKPKSSKKPSAKKSDSESGNSTKKEAKRKREP-------SVTSDVEKTPPQSP--EEEDDDGVQKRRSSRQVKRKRYTEDLEFRISDD--------------DDGDDSAGPKSP---TTSEQQ------------------------------------------------------------ELPDAEGPVVEKIMGMRMGKKELASGEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IEVEEFYVKFKGFSYLHCRWADIEELEK-DKRIQQKIKRFRAKQALST-FVTEMDDEPFNPDYVEVDRVLDVSESTDEN-GELVTLYLVKWCSLPYEDSTWELKADIDQVKIEEFERV--MAREPQLKRVERPPTSDWQKSESSREYKNANALREYQLEGVNWLLFNWYNTRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRKTIQAYEMYYRDTQGRIIKGAYKFHAVITTFEMILTDCPELRNVPWRCVIIDEAHRLKNRNCKLLEGLKMMDMEHKVLLTGTPLQNTVEELFSLLNFLEPDRFPSESTFMQEFGDLKTEEQVQKLQGILKPMMLRRLKEDVEKNLAPKEETIIEVELTNVQKKYYRAILEKNFAFLSKSGAGGGSGGGGGSNVPNLLNTMMELRKCCNHPYLINGAEEKIMEEFRETHPLDQPEFHLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSRPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENAANGVQQLSKKEIEDLLRKGAYGALMEEEDEGSKFCEEDIDQILQRRTQTITIESEGKGSTFAKASFVSAGNRTDISLEDPDFWQKWAKKAELDLDAING--RNNLVIDTPRVRKQTRHYSSMKEDDLMEYSELESDSEDKPIQKPRRPQDRTQ--------------------------------GYPRSECFRVEKNLLVYGWGRWGDILSHGRFKRPLRERDVETICRALLAYCLLHYRGDENIKGFIWDLITPTEDGQSRTLTN-HSGLSAPVPRGRKGKKGKLPVAQTRMPQADWLADCN-----------------------------------------------PDLLLQEDSYKRHLKHHCNKVLLRVRMLYYLRQEVIGDQADRILEGTDSSELDIWIPQPFHADVPTDWWDLDADKSLLIGVFKHGYEKYNSMRADPTLCFLERVGMPDA-------------------------------------------------------------------------------------------------------------------------------------------------KAIAAEQRGADMMADGVEG-----EEEDPE----------------------------------------------------------YKPLRMSFKDDLDDFTNSPLDDNNDGMDGETGEAPKLGENGKPGNLYWPPASALTARLRRLITAYQRTHKREQLRQEAMAKPDRRRR---------RPRDDILAMVTEGGAYVPDGAVAFMADGGAFMAKGSPFIPDSAALLADSAAYFKERR-----------------------------------------------------------------------------------QRWTRREEADFYRVVSTFGVVYDV---------HRQCFDWSQFRAFARLDKKTDESLEKYYCSFVAMCKRVCRMPLKSETELPDPTIIIDPITEERASRTLYRIELLRRIREQVLPHPLLEERLSLCQPSPDLPAWWEPGRHDRDLLRGAAKHGVSRTDYHILNDPELSFLEAYRKFTQGKGVELP-VIVSDPLTPLTLPKDEEVKEEQGDVTLPKVENGSIEDVKEEKSEALSPKKEVKNEEDENGLGPKQEPKEEKMEVEEKDVTEFKTDVEQVCPVDGMVEKKPMDQEPTDTLPSSEDKNAQDE---------KELPTGNKLSTEKASEDEEEKMDEDDKSEKSSQAEVGALSERKNFDEESNASLSTAR---------------------------------------------------------------------------------------------------------DETNETRDCFSVDDVEPSASQMFS---------------------ERS-LFSFWPKDRVMINRMDNICEAVMKGKWPSNRRQ------------------------FFDFPGLLPGYSSMATESPLQRRSLGDLSLVGQTSYSGSEDLTMSPQVNKDDALS------------------------------------------------------LSVPRQ------RRRRRRKIEIEAERAAKRRNLMEMVAQLRES---HAEGQAQ---------------------------------------------------------------AIDLTKALHSVSSSSS-----ASAFPG---AMASSATLKAQMELLQPG-ASSRPR---ANGSLLDTELPNRRKRGRRKNVEGLELLFMGNKRG---------------------------QLSAELSDGTKAFVDGRTH---LAMPSPAQKASGE-----GLDEGS-LQGEDGSS--------------------------------------------------TKDLREWLRQHPTYTMDMPGYVPK-----------------------------------------------NEDLLLSQFAKPKQKRHRCRNPNKIDINTLTGEERVPVVNIRNGRKMGGAMAPPMKDLPRWLVENPEYAIAPDWTDIVKQSGFLPESMFDRLLTGPVVREEGVRRRGRRPKAEIAKATAAAQAAAAAAAAATTSG----------------------------------------------------------VNPLLMNGLFGSMDLTSLQGLQNLQSLQLAAGLMGFP----TALGGGADAKHAAAMLPLMLPGMGGLPNMFSLGSLFGGNLAAAATATNGASSTEQAESEENSK---------------------------------------------------------------------------------------PKTDEETKGEGDEKEEKQAEKSSETVESADATG-DAAALNAAAAAAAAGMSTGTLAFNPFLLSTMAPGLFYPSMFLPPSLGGLAIPGFPQASLADLQSAVSGALGATGEDKESDKGPRTN----QDPNASVADVETADNTLEDSDSEESQNKTADSSVLDDDLAGPAEEMDSMEGGMDDEDDDDDDDDDDPADEDDKSD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z002-1", "uniprot_id": "B7Z002_DROME", "id": "B7Z002-1", "name": "", "aln": "MDGNAQNMFHGNHQGDPYYRYDAAAAAAAAAAANPRAMGPPGGYPPRHRPPHPLQQQPQYPSYQPTAENLYGLGAADHQAAMGLGVGVGVGAGMGDLSGWGAAPSVPGQAAAYPGAGLGAYGHPQAAPPSQQQRQSNASAYRQHMPAYGQQDQQKLASYGAQQSMMAGYGSLAPQQQQQQQPPTPQQQQQAQQVQQQAQQQQQQQQQQSQQQARLPQHYPQAPGQHPLYPGVGAPTVQAGQPPTPQAYAHSPYGSPMQHQPSRGAPQHVGYGHTGLDQASAYGQHVPGGAPPGHHLSAQQQQAAQQLGAHQQQQLQSQQQQQAQQQQPHVSLMQQQQLPGAGLPPPHMGMPPSYGSHHQQQQQQQQTQQQQQQSAPPYMSSSKHQQAAAQLNSSPQYRAPFPQLSPQMSPRPPTMSPHPQMSPRPVGVSPAKPPPPQQQQQQTQAQQPQQVVSNQPSQHSIQGMVGLPSPRPQPPTSGAGGAGAKGPAPVAAPVNTLQALEQMVMPSQALGLPPMDYPSAYRSAVGPRMPASPQQQQQQHQQWGAAHGAQHLAALQQQQAQQQQQQVQQQQQAPPQQQQQAAMLQAQQQHHQQQLSMYGQPMGQQPQTAQQQVVPPVTSQPPVVAASQQQQQQQHQQQSLNDQLQHSINDIVGGGNSSGATGGAQNQHQQQPQLAAMSSPLHQQNLPNMHHLIQPTMETTQPTQQQQQTSQQQQQPQQPQATLTSPHHQQMQHQSPIHQQQQSPHHQQHLPSYNQSQQQFDPFANILGDNQPAASQQTMSPAHVSSPVPAQMQQQQHQTQQQPSQQVPQSQQQQVSQPQQQTQQQQPSTPSHHLSSILNETANSNDSSTLAVAANDSNNSSSNSSTNSIVNNQPTSVHDSNSQSSINSSSNNQQQLLMDNTNSHGGNSESAQNAGVDVGLFDNNSMSSNSAAVAAVASNAASAAAALLDSNSQSSNAEFEKNQSEGEGLGVVEGVIANETDLPQDENSVSKTQDITLSTELPTIQDDLQEKPTAEMEQTQLGQSLGDLSKSLLEEPKTVEESGEDKSQSAPGVAPPADPIIPVTQPPQQQMPPIGMPMHPIAPGYEAQAQGQGHMPPMMPPYGGAPGMYPPYPMLHQQEIAALQQQIQELYCMPPGHELQHQDKLMRMQERLNLLTQHEVNDQCAGGPQCLLFQNVPPMYGPPGNPLLNQQMVESPQVSSTTGRGRGKSANKPRKPRAKKGEKAQVGQQQDLMDISGNVAMGAANAVSSIPTTQLPVSEDCVTQGAGDTSVVGMLEYSEGMGDLSQDVHSANELDTSTDGSGKKKKPRKPRTPKDPNKPPRDRTPKAKKPKDPNDPNSTETPAAVKKRAGASKRRKQYGEDGAEQTGEGSEVEDNKPLVPKAGSADGEAETTSGGTGVDGESPDYDDIPVSKIPRGSNEDEKEAEAGDETVDSVPDSAGDPASTPSRRDRKRSTARSRRNANSEEGGSARKNRGSLSAKALKKRRNRGRIVPESDGEDDTLDRTPPPSPPPDSEMDS--NKRRSSRNTQRKKYIDDVMLRFSDDENSLLVASPVKKDKKPSANASNSNAGSDVEKTEPQSGAEGDAAQEVGEEKSNLPLDESSQLEASSSTSAVAEKERQISTDAANAAMSSKPNYVYINTGDEDSMVVQLVLAMRMGKRELILDKPKEKAPEPKQDEEKSELDEATTDKPEGDEKFKTEGESKKDLTDSEETKLESSAMEVDSKEESEPDDSKKSDEDNKDKDKMEVDDEVGKSDKESKPEEQSETVKTEENSKAIEEDKSSTVLTADHAKEPETVLEKMEVDEKANDDQSAVSKAEGSDEKSTDDSNPEEATTEKNKESLEIEGEKERVKEGEESVKKENDEKTEADMENKPEPVFIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAAKIRRFQQKQSQQLNIFENIEDEPFNQDFTEVDRVLDMSVHTDETSGETTKHYLVKWKSLPYEDCTWELEEDVDNDKIEQYLRFNKIPQRSEWKSKKRPHPELWKKLEKTPVYKGGNSLRPYQLEGLNWLKFSWYNTHNCILADEMGLGKTIQSLTFVHSVYEYGIRGPFLVIAPLSTIPNWQREFEGWTDMNVVVYHGSVTSKQMIQDYEYYYKTESGKVLKEPIKFNVLITTFEMIVTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISELFSLLNFLEPSQFSSQEEFMSEFGSLRTEEEVNKLQALLKPMMLRRLKDDVEKSLAPKEETIIEVELTNIQKKYYRGILEQNFSFLKK--------GTTSANIPNLMNTMMELRKCCIHPYLLNGAEEQIQYDFKSQHGED-PESYYKNLILSAGKMVLIDKLLPKLKANGHRVLIFSQMVRCLDILEDYLVYRKYPFERIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTAADTVIIYDSDWNPQNDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQSMNTQGSKDGNNKQLSKKEIEDLLKKGAYGAVMDDDNAGDKFCEEDIDSILKRRTQVITMESE-KGSTFSKASFAASGNRSDITIDDPDFWTKWAKKVDIDPDACERDETEDLVLSEPRRRTQIKRYGHEDVMELNSEESSNENSDEEGGIGLRSRRRKEKRDRAREKKGNDEYIPRERDALAALGLEEIQYGNWAKSECFKVEKGLLSFGWGRWSELLELGQFKRGWRDVDVEDCARIILLYCLQVYKGDEKIKTFIWDLITPTEDGEVQKISRDHSGLHNLVPRGRNGGKSNKESTGVSTPAPGSASGSNSGNTTPAHKSSALDGSDKDSGGINASAVAAAVTSIHDPNHWSKKEKYDADAYLEGAYKKHLGRHANKVLLRVRMLYYIQHEVIGDFVQQIKDNTPISELPIRPPPTPDQVPSSWWNPICCDKSLLVGTYKHGCEMYRQMRADPNLCFVTHVGAGAAGDDLAVTSLPINEDDANSKHDDGDEVDDDGTTTTKDSDSTKLTGGDNKDSLLDPERPSSSGKSSSENASGGNDKTESENDATTVSESSYKSEVLPGKGSDLDVSVAQQDALSATPELANTSDPKMNKNDAQVSASVSCDPADSSSPEAAGKAQGTGVQTGDAGELDIESEKKDNEKETKESTGDAPAVEAKKDSAAIARAEGDKTESCTNNATTNISTTTTTTTITNTTTTTNNPSSKAANSNNTTDHANSNSHLGLDEEESVAGSYPPTVAAVEDATTMWPSMQDLNTRLRRVITAYQRNYKKEELKLQQKAKLQALVSSTPPLSVPTTPTLQSMQMQLQSGSGSGGSGIGSSAQHDASGRSLQALMQSQGASTSAAAAAAASSAGGSCSGSGQVGMGGAGVMPAMPTAADISLMLSILNTTDVNQLANLDINKLAMYLVSMNNKMERQGKMELAAKERESQRLQLIPKKWNRREEYEFLRVLTGYGVDLHVSTPMASSNGSSLSPDWTKFKQMAHLERKSDETLTDYYKVFVAMCKRQAGLKLSESER--GLEGIIEEIEKEHAKLILDRLEVLAKLREVAR-NPMLEERLKLCTKNADTPDWWEPGRHDKELITAVLKHGLYRSETFIFNDPNFSFGESEKRFIRELEAQIQRTIKLEAFNAEKAEKLAAAEKDAATEKAAATEKAAAEKAASVKNEVIDLDDELMTNESVIKKESPVTPIKEEIKSEESPEKHDTADNLEDKNSDAEESTKIKGKEDFNPETTEKEALDESTNLNKDKSSTETLVPEIEDSKPSEDKMEVEELPVAENGEKEGSPEKCSDAEDKKFSEEKPSSPAVPDGKVSEMEADEAAPNTEENCSGDSESPEKECEDKVVEKVEEEKGENSYEKAEEQKEETEKLEKSSIESEPSEKSETVLEPEVAVPKKSTGDQDILDLVAGPSDPDDDEVMKEKEKAVEEECKKQAAELKARFPDLEVIQPATVKQQKLEKPKLEMCMIRWFKDFALERRIAHIVACVESGNWPVDSKYSAFATCKGATDLSIALHESIPHLSSLERRSTTPDVITITTDQGVTKHLQTSHMQQVASSASAASTSSGVPQVTQSKPSSSNSLPGLDAKSINAAVAAAVAAAAAGGNATSLSSLLPGMSLSAATGSSAGGVSGLSVPSAGSGVGKKRKRHIAIDVETERAKLHALLNSSTMAPKDWESEIANMEALSGSSGRGRGGNSSASSGMQPPPAHQHASLSRQSSGQFSKPAVPAMKTPPPSMGAPMDLSSSLPKMNMTEMLKSASSSGAIDLSEVQDFSMPSKKSSVHAALSSAFPSMGNKSKLDDTLNKLMKKNNCTIEEPVIGKEKKRKKLDEIVLGLSAAKEQKTFPDPSLPSSKKPQIPPSVSVTPANLQSSSNQQSNQKPFTITVTTVPGKSKSGSSNSGSGTGGSSSASGGGAGGSGLSALQNMAMGGLSSKDSLNALLAQTMATDPQTFLKQQQKMMQFLPPAQRKAYENMLAEMEQAMKISSKFSTNSPHDVKVNKWLSDMTSPLGDQLSIDYVGGGGASGSGSGNSRRSNRQQGNSQQSSSAAQLQKQQQQQQQQQQQQQQHSMPGPQNLTGEEPVPVINKQTGKRLGGNKAPQLKRLMQWLTENPNYEVDPKWLEQMQNPMSTPSPRPASMESG--YGSSAVKSHGGRPLSNLSSTSSSSHTQQQSSAAQSQAGGNSGSSKKNSRQQTAASAALDQAALQFGSLAGLNPSLLANLPGLGAFDPKNPLAAFDPKNPLLSMSFGGMPGMGNIPGLGNLNNMNLFASLAGMGGLGNLAGMDTQSLAALMAAAGPTLGGLTGASGGAGSGKSQAQSQSSATSSSSSASKKKQQQQQQQAQNEAAQLAAAISASTGGSGASGGKNAAASASQLAAGFPFLFPNPSLLYPPMGLGGLNPYSLGSSGLGSAYDQLAQQYNLLNGATSSASNTSSTQSKSHQSQSKSSQSRNTTASANSAASLMNAMASMGGGASTVTTPSTSASGSGRGRQSSSRNQSQTTPTAADMAQLSSLLMPGADPHLLESLSRMSNMDLAQATRLMSSLGMPPLSGTPSSSGGGNTSTSKRSSQAANEANVQAKEQQKWLESLARGALPTDLAALQAFSQGKMPSTSGSNTGTSTSSSKSSKAAATAAAAQLPQIPGMSSDFPQAFLAEMAAQAMAAAGGSLPLSGPGSLASLAGLTGGSAGGGGSSASGSTSHSSSKRQREQDAFKQQMDYYTKTLGLGSGISLIPTSSAGGSSASSSAANAAAAAYAAALDAEQQHQQQQKALSKRARGDLHPTKEELAALAAGLPLNLGASMSSIEKSLRGGSSSSSSSTPAPMTAEQDKVTLTPLNASGGGSGSSSSSAAAAGLAANLPSQTTITIAPPISSGASTSSERSERSESRISLTITNAADAAKLPPPYEEADELIIQPILKKPTAANPGSSHGGSVDDLDTAENTSAANLSGSSSSSAAAAAAAAAEENRRSSNRLKRPRSGNEQGSGSVEGQPPEKRRELRSTRHTRSSADASTLNLSTGSESGAEERNE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .*:* * .. : .*. * . . . . .: .: . . : *: :.* :* *: . * . . . :.: .: . *.: :.: . . * :.: . * * . :. :*:*.. : : * ::. : * . . . . * . : .. :* . : ... .*::. *. . .* . :.. * : **:.. .. : : . * ..* .: * * :* : * : * .* : . : :. . *. * * * :: . ... : . : . . *. : : : * :. *:: ** * ..:* * * * :: .. * :*. : * *. . * :: :* : .. . : * : : . . . : : ** :: :: : .:. : *. .. : . .*:.: *: ::* . : ** :. * . . :::* .*. .: ::..: . . ..... * * : . . . :::*** ** :.: * :******:.:**:* :*: :::**: . :::. .: :* * : * :. **: ::. * *:: .: :::**::**::.******.* *:* * *:*: **:**: **. . :. :::*: ** *:.****::*.: **: ** . ***** ******.*** . *:*: ***:: :. :.:..: : :** .. *:* *.: **. * ** *****:*** *.*** :****************:**::.:* **:***************:***. **::******** :*:: ** ** *:: .*:::* . **:.:*******:** :*: . ** :******************: :::**:***:******.:.******:****.:*.*: **.***.*:***:*:***.:**********:****.***************:******.***:**:**.* * :*:***:********** ****:*****:* :*:. * : *: : :* :***:************.*********************: *:**:******:****** ****:*:*.**********:************* **:********************* * ******: **:**********:************. : . .. :***********:******:*:::: *.********.** ***:.**:*** *****:****.::***:**:::**:** *****.::* ** : ::**:. ** *.* : *. . :* . .. :.:*::: * : : : .:.:****:***.** :***** ::*. *::** : *** .* :* *** *:***:** ********* **: : : . **** *****:* * : . :..* *.:**:** :*.************:::***** .::* :.: ** : * . . .: * .*****:*.:*** * *..***** ***: :** * *.: :*:.: :.. *.:* * . : . .:: :.:** . : : : : . ** . *.:****:******.:*::::: : * : * : : : * . ::*.**** :* **:: :** . **.:*: :*:*::*:**:* .*: *****:* . : . . . . :*: * :*:*. * *:*:* ::** . :* * :**.** . * * *** ****::*: .. ***: *:: .*:***::** :: : * : . .:.. . .. .. . * :* :* **. : : :. . . . .:. * .: * *:: ::.*:....* : :. *.*.**. :* :.. **. :: :: . ..::: : : * ** .: .*: :* .* .*:** : : :: . *. . :.:. : :: . :* *.:. : **:.:... . **** :*:*: :::*:*** : * . . :: : : ::::: :..:** : . * . ::.: : : . : . * * :. :**::: : * : . *. *:: . *.* ....: .. *: * .. . :: : :: . :: : * * . * . : :*:::: :: . . :.***** ***:* :.*:::** ** :* * :** ***:: : *.* : :::. *.. : :* ... :* ** :::: : ::*. : :* **** .: . .: .: .* **:.::* . * *: * . * * *: * .. . * ::*: :. **. * : :: .:. : *.. .:.:. ::.::: :..:* : * . .*::..: .: . : . *: . *: . *..* :** * .*. . : . : .. : : : :: : . ::. .*: . :. ::::. * . .: ", "identical_positions": 890, "similar_positions": 893, "identity": "16.08%" }, { "cls_id": "homologset.agr.MGI:2444752", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LVF9-1", "uniprot_id": "F1LVF9_RAT", "id": "F1LVF9-1", "name": "", "aln": "MGGCVGAQHDSSGSLNENSDGTGGLDLPIRSAGLAVALGR---NQPLKKEKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGANITLPHGALTECYDELGNRYQLPVYCLAPPINMIEEKSDIETLDIPEPPPSSGHESQLRLRLS-TGKDLKLVVRSTDTVFHMKRRLHATEGVEPGSQRWFFSGRPLTDKMKLEELKIPKDYVVQVIVSQP------VQNPAPVEN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGH0-1", "uniprot_id": "UBTD2_MOUSE", "id": "Q6PGH0-1", "name": "Ubiquitin domain-containing protein 2", "aln": "MGGCVGAQHDSSGSLNENSDGTG------------VALGR---NQPLKKEKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGANITLPHGALTECYDELGNRYQLPVYCLAPPINMIEEKSDIETLDIPEPPPNSGHESQLRLRLS-TGKDLRLVVRSTDTVFHMKRRLHATEGVEPGSQRWFFSGRPLTDKMKLEELKIPKDYVVQVIVSQP------VQTPTPVEN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WUN7-1", "uniprot_id": "UBTD2_HUMAN", "id": "Q8WUN7-1", "name": "Ubiquitin domain-containing protein 2", "aln": "MGGCVGAQHDSSGSLNENSEGTG------------VALGR---NQPLKKEKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGANITLPHGALTECYDELGNRYQLPVYCLAPPINMIEEKSDIETLDIPEPPPNSGYECQLRLRLS-TGKDLKLVVRSTDTVFHMKRRLHAAEGVEPGSQRWFFSGRPLTDKMKFEELKIPKDYVVQVIVSQP------VQNPTPVEN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DG43-1", "uniprot_id": "UBTD2_DANRE", "id": "Q6DG43-1", "name": "Ubiquitin domain-containing protein 2", "aln": "MGGCVGSHHDSSGSLNENSDGTG------------VALGR---NQPLKREKPKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAQAFESNDHELAQAIIDGASITLPHGALTECYDELGNRYQLPVYCLSPPVNMIEEKSESETIEVPEAPASEGQECQLRLRLS-TGRDLRLAVRTSDSVQQMKRRLQTQEGVAATSQRWFFSGRPLTDKMKLEELKISRDYVVQVIVSQPPTTPPLPQNPTPVEN--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNB2-1", "uniprot_id": "Q9VNB2_DROME", "id": "Q9VNB2-1", "name": "Ubiquitin-like domain-containing protein", "aln": "MGACVCRMNPDNETMSVSSASIS------RPASAGIAMGAARKNRPLCHETIRWRSDVPLTEGQLRSKRDEFWDTAPAFDGRKEIWDALRAATTAAEGLDFQMAQAILDGANVSVPNGYLTECYDELGTQYKVPIYCLSYPINIVKEENGRDSPAEYSEPVDGGTDIFLKLRISSTMTDVKLPVYSKDTVGQCKKKLQAAEGVDACCQRWFYSGKLLGDKVPIDECSIHQGYVVQVIVNTEHYN---HDNSTSTAHAS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.** : .. ::. .* . . :*:* *:** :*. :*:** *:*:*****************:*********:**: * *. *.::****:***.:::*:* *********.:*::*:***: *:*:::*:. :: . * . * : *:**:* * *::* * :.*:* : *::*:: *** . .****:**: * **: ::* .* :.*******. :..:.. : ", "identical_positions": 108, "similar_positions": 79, "identity": "41.86%" }, { "cls_id": "homologset.agr.MGI:2444763", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVT0-1", "uniprot_id": "ZN418_RAT", "id": "D3ZVT0-1", "name": "Zinc finger protein 418", "aln": "MKAKKTVGSSGSCVRAPALSTEPMAAVKHLAQIPRCTETGMICTQGCVTIEDVTVYFSQEEWKLLDEAQRLLYLDVMLENFTLISSLVYRYEAEAEEKTCAQSLSQTEAPQVRTPKQGQLRQKPHPSDICITVLKDILHLNDLPGQKPYLTEVCTKPQDHKHHRAKNWLKRDVDSLVKSCIFHVAGNPFICSKIGEKFPAIWNLLQPKDIPNGEKQNKIKRGKAFHRDKNNSESDEYKKSSSPQHRLHEYPGVCSAKGGFESNSCEQDLNKYSPAPFRMDQTENRPYECHVCGKWFGQKATLRIHQRRHTGEKPYKCGECGKSFCQSSNLSEHCRVHSGERPFECLECGKAFGCHSSLLRHQRTHTGEWPYECSDCGRLFRQIVSLITHQRTHTTEKPYECGQCEKSFSHKATLTVHQRVHTGEKPYHCEACGKSFSQSANLIKHSKIHTGEKPYECGECGLCFRQRATLMKHQRTHTSERPYECRECGKFFKQYFYLIEHRRIHTTTEFYECEQCGKSYTQKATLIRHQRVHTGESPYKCEECGKAFEYKSRLKRHQRTHTGERPYECAKCGKFFRESYNLAEHQKIHTKAKPYHCDQCGKCFSRRADLVKHQRVHTGERPYTCGECGKTFSRTTNLVQHRRIHTGERPYECDQCGKSFSQVSTLTRHQLLHTGEKPYKCSK----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A7D0-1", "uniprot_id": "A0A8I6A7D0_RAT", "id": "A0A8I6A7D0-1", "name": "", "aln": "MKAKKTVGSSGSCVRAPALSTEPMAAVKHLAQIPRCTEAGMICTQGCVTIEDVTVYFSQEEWKLLDEAQRLLYLDVMLENFTLISSLVYRYKAEAEEKTCARSLSQTEAPQVRTPKQGQLRQKPHPSDICITVLKDILHLNDLPGQKPYLTEVCTKPQDHKHHRAKNWLKRDVDSLVKSCIFHVAENPFICSKIGEKFPAIWNLLQPKDIPNGEKQNKIKRGKAFHSDKNNSESDEYKKSSSPQHRLHEYPGVCSTKGGFESNSCEQDLNKYSPAPFRMDQTVNRPYECHVCGKWFGQKATLRIHQRRHTGEKPYKCGECGKSFCQISKLSEHCRVHSGERPFECLKCGKAFVCHSSLLRHQRTHTGEWPYECSDCGRLFRQIVSLITHQRTHTTEKPYKCGQCEKSFSHKATLTVHQRVHTGEKPYHYEACGKSFSQSSGLNNHSKIHTGEKPYECGECGLCFRQRATLMKHLRTHTSERPYECRECGKFFKQYFYLIKHRRIHTTTEFYEYEQCVKSYTQKATLIRHQRVHTGESPYKCEECGKAFEYKSRLNRHQRTHTGERPYECAKCGKFFRERYDLAEHQKIHTKAKPYHCDQCGKCFSRGADLVKHQRVHTGERPYTCGECGKTFRRSTHLVQHRRIHTGEKPYHCEACGKSFSQSSGLINHSKIHTGEKPYKCGECGLCFRQRATLMKHLRTHTSERPYECRECDHWHESKYEENPSVQSIYVEILQARTPKASLLNRKTHPSDICAPALTDILHLNDLPGQNLFFAETCSILQGQEHHNAKNPLREMWTLTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFS8-1", "uniprot_id": "ZN418_MOUSE", "id": "Q8BFS8-1", "name": "Zinc finger protein 418", "aln": "-----------------------MAALKHLAQVPRSTEKGMVCIQGCVTFEDVAVYFSQEEWELLDESQRLLYLDVMLENFTLITSLAHWSEAEAEDKTCA--------PQIRTAKEGLPTKKPHPSDICSTVLKDILHLSDLPGQKPHLTEVCTDLLDQKHHRAKNWLKKDVDSLVKNCIFHVAGNPSVCSKIGEKFPAVWNLLQPKAIPKGEKQNQIKCRKAFHSEKNNSKSDKYNKSSSPQHRLHEYPRLCSGKEGFESNSCEQDLNKYSIAPSQTDQTENRPYGCHDCGKWFGQKATLRIHQRRHTGEKPYRCGECGKSFCQSSNLSEHCRVHSGERPFECLECGKAFGCHSSLLRHQRTHTGEWPYECGDCGRLFRQIVSLITHQRTHTTEKPYECGQCEKSFSHKATLTVHQRVHTGEKPYHCEACGKSFSQSANLIKHSKIHTGEKPYKCGECGLCFRQRATLMKHQRTHTSERPYECRECGKFFKQYFYLIEHSRIHTTTEFYECGQCGKSYTQNATLIRHQRVHTGESPYKCKECGKAFEYKSRLNRHQRTHTGERPYECAKCGKFFRESYNLAEHQKIHTKAKPYNCDQCGKCFSRRADLVKHQRVHTGERPYTCGECGKTFSRTTNLVQHRRIHTGERPYECDQCGKSFSQVSTLTRHQLLHTGEKSYKCSK----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:*****:**.** **:* *****:***:********:****:****************:**.: :****:**** **:**.*:* :******** *********.*******:******. *:**********:*******.****** ** :**********:******* **:*****:** **** :****:**:*:************* :** * *************** ** : *** **** ** ************************:********** *:*****************:***** ********************.*************************:**************************** **********:.* :***********:***************** *************************:* ********** ** *****:******************:************:*********************** *:**************:********** ************************* *:*:***********:**.*: ******* * * .*. :*****.***.: ", "identical_positions": 551, "similar_positions": 59, "identity": "68.79%" }, { "cls_id": "homologset.agr.MGI:2444764", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q2S6-1", "uniprot_id": "E9Q2S6_MOUSE", "id": "E9Q2S6-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANSNSQDMVCGSVTFRDVAVDFSQE---EWACLDATQKVLYRDMMLETYSNLVAVVGRCISK---PDLIVLLEQEKEPWMAVKEETDRPSPDLETD-YDAENISPE-------NPINNKKFLKQSIKQL-ITFDPKDSSTSIGPNYS-TFHGLQDCQ-SDAGQQITNKEGVPPHT-CQTLAHNTEKPYECK-----------------------------------------------------------------------------ECGKCFGCRSTLTQHQSIHTGEKPYECEECG------------------------------------------KAFRLPQQLTRHQKSHSGEKPFECNECGKAFHLPDLLKYHKTIHTGEKPFECRECGKSFNRVSNLVAHRIIHADVKPYKCSECGKAFKRR---------------------------------------------------------------------------------------------SNLVQHQKTHSDERPFQCKDCGKGFIVLAQLTR------------------------HQNIHTGEKSFECHECGKAFRLPQQLTRHQKSHSGEKP--------------------------FKCNECGKAFHLPD---LLKYHKTIHTSTKPFECRECGKSFHRISNLVEHRLIHADVKPHKCNECGKAFKRSKSL----------------------MQHQKIHSGERPFQCQECGKAFIVLTHLTRHQTIHTGEK-----SFECNECGKKFRTATHLVMHQTIHTGEKPFECNVCGKAFRLQVYLSEHQK----------------IHIEEKP------FKCKLCGSAFRRKYQLNEHYTIHTDEKP----------------------------------------------------------------------------------------------------------------YQCKECGKCFRQRSNFTEHQSIHTGNK---PFECKECGKFFRLNTLLIRHQKS-HSSERPYKCKECGKAFHLPSELNNHQI-VHTSNRPFECKVCGKSFKRESTLIQHSVIHGGVKSYECNECGKAFIHRSSLFHHRKIHSDEKPFKCQECGKAFVVLAYLTRHQSIHTGEKSFECQ-QCGSAFRYKSQLSKHQRSHTDVKLFQCMEGGNDFVHGTNLSIHQGIHTSENPFQCNEYGEAFKYHYQFPWTF---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A327-1", "uniprot_id": "D4A327_RAT", "id": "D4A327-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSSSQHMACGSVTFRDVAVDFSQE---EWACLDATQKVLYRDAMLETYSHLVTVVGSCLSK---PHLITLLEQEKEPWMAVKEETDRPSPELETG-YDAENISPE-------NPINNGKFLKQSIKQLSRTFDFKDSSSSNGPNYS-AFHGLKDCQ-GDADQQITNKEEMPPYT-CQTLAHNIERAYECK-----------------------------------------------------------------------------ECGKCLGCRSTLTQHQTIHTGEKPYECKECG------------------------------------------KAFRLPQQLTRHQKFHSGEKPFKCNECGKAFHLPDLLKYHKTIHTGTKPFECRECGKAFNRVSNLVAHRIIHADVKPYECNECGKAFKRR---------------------------------------------------------------------------------------------SNLVQHQKIHSDERPFQCKDCGKGFIVLAQLTR------------------------HQNIHTGEKLFECHECGKAFRLPQQLTRHQKSHSGEKP--------------------------FKCNECGKAFHLPD---LLKYHKTIHTGTKPFECRECGKSFNRVSNLVEHRIIHADVKPYACNQCGKAFKRQKSL----------------------MQHQKIHSGERPFQCKDCGKAFIVLSHLTRHQTIHTGEK-----SFECNECGKKFRTATHLVMHQTIHTGEKPFECNVCGKAFRLQVYLSEHQK----------------THIEGKP------FKCKLCGSAFRRKYQLNEHYTIHTDEKP----------------------------------------------------------------------------------------------------------------YQCKECGKCFRQRSNFTEHQSIHTGNK---PFECKECGKSFRLNTLLIRHQKS-HSGERPYECKECGKAFHLPSELNNHQI-VHTSKRPFECKVCGKSFKRESTLIQHGAVHAGVKSYECSECGKAFIHRSSLFHHRKIHSDEKPFKCQECGKAFVVLAYLTRHQSIHNGEKSFECQ-QCGSTFKYKSQLNKHQRSHTDVKLFQCMEGGNDFVPGTNLSIHQGIHSGENPFQCNEYGEAFKYHYQFPWTF---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O75290-1", "uniprot_id": "Z780A_HUMAN", "id": "O75290-1", "name": "Zinc finger protein 780A", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHGSVTFRDVAIDFSQE---EWECLQPDQRTLYRDVMLENYSHLIS-LGSSISK---PDVITLLEQEKEPWMVVRKETSRRYPDLELK-YGPEKVSPE-------NDTSEVNLPKQVIKQISTTLGIEAFYFRNDSEYR-QFEGLQGYQEGNINQKMISYEKLPTHTPHASLICNTHKPYECK-----------------------------------------------------------------------------ECGKYFSRSANLIQHQSIHTGEKPFECKECG------------------------------------------KAFRLHIQFTRHQKFHTGEKPFECNECGKAFSLLTLLNRHKNIHTGEKLFECKECGKSFNRSSNLVQHQSIHSGVKPYECKECGKGFNRG---------------------------------------------------------------------------------------------AHLIQHQKIHSNEKPFVCKECGMAFRYHYQLIE------------------------HCQIHTGEKPFECKECGKAFTLLTKLVRHQKIHTGEKP--------------------------FECRECGKAFSLLN---QLNRHKNIHTGEKPFECKECGKSFNRSSNLVQHQSIHAGIKPYECKECGKGFNRGAHL----------------------IQHQKIHSNEKPFVCRECEMAFRYHCQLIEHSRIHTG---------------------------------DKPFECQDCGKAFNRGSSLVQHQS----------------IHTGEKP------YECKECGKAFRLYLQLSQHQKTHTGEKP----------------------------------------------------------------------------------------------------------------FECKECGKFFRRGSNLNQHRSIHTGKK---PFECKECGKAFRLHMHLIRHQKL-HTGEKPFECKECGKAFRLHMQLIRHQK-LHTGEK------------------------------------------------------------------------------------PFECK-ECGKVFSLPTQLNRHKNIHTGEKAS--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y6R6-1", "uniprot_id": "Z780B_HUMAN", "id": "Q9Y6R6-1", "name": "Zinc finger protein 780B", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHGSVTFRDVAIDFSQE---EWECLQPDQRTLYRDVMLENYSHLIS-LGSSISK---PDVITLLEQEKEPWIVVSKETSRWYPDLESK-YGPEKISPE-------NDIFEINLPKHVIKQISKTLGLEAFYFRNDSEYRSRFEGRQGHQEGYINQKIISYEEMPAYT-HASPIHNTHKPYECK-----------------------------------------------------------------------------ECGKYFSCGSNLIQHQSIHTGEKPYKCKECG------------------------------------------KAFQLHIQLTRHQKFHTGEKTFECKECGKAFNLPTQLNRHKNIHTVKKLFECKECGKSFNRSSNLTQHQSIHAGVKPYQCKECGKAFNRG---------------------------------------------------------------------------------------------SNLIQHQKIHSNEKPFVCRECEMAFRYHYQLIE------------------------HCRIHTGEKPFECKECRKAFTLLTKLVRHQKIHMGEKP--------------------------FECRECGKAFSLLN---QLNRHKNIHTGEKPFECKECGKSFNRSSNLIQHQSIHADVKPYECKECGKGFNRGANL----------------------IQHQKIHSNEKPFVCRECEMAFRYHYQLIQHCQIHTGGK-----PFECKECGKAFSLLTQLARHKNIHTGEKPFECKDCGKAFNRGSNLVQHQS----------------IHTGEKP------YECKECGKAFRLHLQLSQHEKTHTGEKP----------------------------------------------------------------------------------------------------------------FECKECGKFFRRGSNLNQHRSIHTGKK---PFECKECGKAFRLHMHLIRHQKF-HTGEKPFECKECGKAFSLHTQLNHHKN-IHTGEKPFKCKECGKSFNRVSNLVQHQSIHAGVKPYECKECGKGFSRVSNLIQHQKTHSSAKPFVCKECRKTFRYHYQLTEHYRIHTGEKPFECK-ECGKAFGLLTQLAQHQIIHTGEKPFKCKECGKAFNRGSNLVQPQSIHTGEKPYECKECGKAFRLHLQLSLHQKLVQVRNPLNVRNVGQPSDISSNLLNIRKFILG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VL91-1", "uniprot_id": "Q9VL91_DROME", "id": "Q9VL91-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METESMAPSSSAAAAATKLLVEITTDGIPKLHCPVCNKALVSLAGYVKHVKKHQPPGGFECRH---CDARFCHEEELTQHAKDEHGVTGAVAGQERKPFVCEKCGAE-------YKYQEAYRRHCRTKCGEEKLPREESRPMECKCCYTRFSSASNLSKHRRSRPDTCGQPEYDSP-GSSDGMKKHKAFRKK-----------------------------------------------------------------------------DRNRDSDDEDTTSEESEDSDDDIPLASRLKT------------------------------------------KLKQESQNSDSGDECPDFEPNNSEDDADASGFQLPPPAMVKVEAFDEEDFEYQDASMYVKTESTDIFSNEKDKLLDVLLN--EGDGLKPF---------------------------------------------------------------------------------------------ESLKVEQGAGILDEIAAVPLVEVAEEDVLELRG------------------------HQMEKPPGPRKRGRPPKEKIPVVKRKYRKRNAPRSPSP--------------------------DDSSGTPKRVAKISKKELKERLKMINKMEKSWKCPHCVKIYHIRKPYEKHLRDDHKLNEAEMKEIFKDVD------------------------------VHAKLDEEVFKCPICSKIYLVEKRLVTHMKVHGEDGKL---TFKCPCYCNLFFATKEQATEHARAQHKELLYCEKCDKYMTGHDSLKNHERN---------------FHSKKEPRSQQRNLICDKCGKKFTGRTSLSDHVRSDCGRLPL---------------------------------------------------------------------------------------------------------------YGCSVCGKHLSTAGILKTHMLLHKADT---PYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMT-VHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCG------------------------------------QLPLNAKATQYMGVQRGKLLMGAKPEAGMEYEETKTLIAQDVIDRDMPMAQELNFPSDGSAPLATVPLNYASTHLVPHIVLQTMQAEARRME--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4K7S6-1", "uniprot_id": "A0A0B4K7S6_DROME", "id": "A0A0B4K7S6-1", "name": "", "aln": "MSANRRRRSASAASSIAAETATAATAATAEAISTAPSKEQLSPPIAGGSASADEDLLEMPRICRCCCKRDLKLLGLFEASQPTLANTTVASASAAASVASNKSSGTLAKTCATEAETETPQTLSANPVNPGTKATSSPSEAATTLSTSTRPASASFSSTSFSTSTSPMRRRTTNTTAPSASPAPRGRSSDNAVDYTLSGAHSSMDIVLEEMTIWMLNINRDDGLPQEICRQCMAQFLMVAKFRRKCVRMQQRLQDFAQEISDRQTARQAKRQQKVQKKTHDRWLQLEPTSHEEQQPIRKRRMVSESDGDSTAAAAAAEAATATATTPAKQVRTDFESLPPPKPSPQQHRVRKYRTLSIDCEMERPAASINASSMPWKTKAARKELSENWASSCSTAVMSPNRQRSSTSSSEHMSDLSVGPCCGFESDSNPSSTSNSARRTVILVKQQSPEKTSPMYDLMPRRGRRPRKAPIYMPAKRQRRSLVRKEPLYRKAQPVNEENKKSDQKDIYPKESRMEGLAPSCDEAIDSTSDAPMEVASNVVQKKCDEICLNGLIDSRNQLGAMEMEPVNEMIASNGVDKELTLSVQNNKETTSEEQIFEATSVIKESVQPEQSAEDIQVRTEIESIANDIRAEADLVQSEELTSSTETSESQPKAVEQLESMGKQESYALPQNMEAHESVQQTQTVDESDSADQREIIVSIPLEVLDENLQRRLCVDPETEAANRQSADPKEFALRPDDVNNNENDENFCQSATADSFNSAVALRTNKIEATPPGGTDSDDTDTDEVPIVPSGPTPMDFMAEFAKHCANGIEQLKVTTPVPSPTPSDLVPLNDLEAKQKLEVEMNDVETTLNGILNEMQDQHMYTPNCAHIDEFLTPADYATLTEQESSVSSPPNPFEQSSVAEPKDEKPSATEDPFDNSNFTNELIGFQNDIPCFENIETPEEGQNLHLELTQFLRDLQPSQSDPPAGEQVEKIEMETQPSTVQMDVQSNLPVQAADTQPQNESANHSPFESPISSPQVQSQIELQMEPQIETQMQPQIETRMQHDVLSVQSPQNHQPQVQSHDQSQMQHQIPPQIEPQIEVQNQEQNTLQLVPQAQHQVVPHVQLQSQLVPHVQTQGTTTTVTYEQIYQQHIVQQTVQQSSNKMQVISLPSAGSETTRQWQTQQSQQQQQVQWSSVGGLEAIKSAPVESVAPTTTTYYISASDLYPQQTETYTMLQPASNESYVIEQVNHQQQHCQQQIQMSQQQHQRQHQQQQAQQQQQPIMILIQQPEIQQPVASASNPQQAPLHIYNAATSNDVHQMQHTQRQQIRQQYQHQQYQRLQQPQQTRVVQSHPVLGMPGATSISTKVTPIPVTAARGRPLTLKCRFCHNGPRFSSSLEYSRHIIDLHPAVAPFNCPHCPMAFAGRTKRSQHILSHHVVQQYQCGQCSHVFPAQKALDVHIQRFHMTLKTDPSGAVKVEDVQLQITSERRPRGRPYKPRLQLQQHQLQPQQKLQVQQHQQQQKALQQLPQAQHHQQQQQPQLQQEVLQQVQQLQVQVQPQQHQQHQQVLQVQQPQQQPLMQPQSPHPSTVEMQASPTTPRKILCCPDCEDCTSGHSHANEQFEELQTLQAPPTVLTPPSTIVSVPSPQPMVYSQHITMPSPEQSEPDSTTTLRQYRKRGVIVGPQGPLHLATPVASPSPSSSPSSSTVDHIPPASPATPASPAPPPSPAVASTVQVSELRTSHHCLYCEERFTNEISLKKHHQLAHGALTTMPYVCTICKRGYRMRTALHRHMESHDVEGRPYECNICRVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHIKFHG-ELGYQCDGCDRTFEYLKELRKHRRTHS-EMFYKCKFCPSSFMRFTNFRAHMKTHLPLGVFRNEDAASKSPSNNNSHASSDKLENPATPIEETPLTPMSSGGHLYHSPDEYPNSVESCAGNSVALESYATTP--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.. : : * . :. . . * . . . . . * .. . : .: . : . . .. * : : . .. * . : . : * . .: : : :. . . : .. :: .* :. :: * :. . : : : : : .. : . . :: .::* .* : . :* . :: : : . : .. :* : :: : : : : : : : . .* * * . .:: . . * * : : :. * : . *: * * : :::. * : . :*::*: * : .* * :* : : : .. . . . ", "identical_positions": 28, "similar_positions": 135, "identity": "1.4%" }, { "cls_id": "homologset.agr.MGI:2444772", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80Z36-1", "uniprot_id": "ZHX3_RAT", "id": "Q80Z36-1", "name": "Zinc fingers and homeoboxes protein 3", "aln": "MASKRKSTTPCMIPVKTMVLPGASTEAQPVEPLPEGPQQDLPSEAPEASSEAAPNPSSTDGSALANGHRGTLDGYVYSCKECDFRSQDVTHFVGHMTSEHTDFNKDPHFVCTGCSFLAKTPEGLSLHNAKCHSGEASFLWNVTKPDNHVVVEQSVPENASSSVLAGES-TEGTE----IIITKTPIMKIMKGKAEAKKIHMLKENAPTQPGGEALPKPLAGETEGKEGDHTFINGATPVSQASANSTKPPHTANGPLIGTVPVLPAGIAQFLSLQQ-PTVHPQHHPHQPLPTSKALPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASAGNVQHLIQAA--LPGHAVGQPEGTAGGLLVTQPLMANGLQASSSSLPLTTASVPK-PTAAPINT-------------VCSNTTSAVKVVNAAQSLLTACPSITSQAFLDANIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRR----YHCRNLKGTRAMVPGEHGSVLIDSVPEVPFPLSSKVPEVPCVPTATSLVSHPATKRQSWHQTPDFTPTKYKER----APEQLRVLESSFAQNPLPPEEELDRLRSETKMTRREIDGWFSERRKRVNAEETKKADGHAPQEEAEGAEEEGRDEELASELRAPGEN---GSSEMFLSHTLAERKVSPIKINLKNLRVTEASGKSELPGMGMGVCEPEEDGLNKAVEQPPSRVSYKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALK-------------NGQLKWYEDYKRGNFPPGLLVIAPGN----RELLQDYYMTHKMLCEEDLQTLCEKTQMSAQQVKQWFAEKMGEETRAVADTSS------EDQGPGHGEPVAVDKVLGDACAALSENSEAWEPSAPEAGSEPFDTSSPQSGRQLETD------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0Q2-1", "uniprot_id": "ZHX3_MOUSE", "id": "Q8C0Q2-1", "name": "Zinc fingers and homeoboxes protein 3", "aln": "MASKRKSTTPCMIPVKTVVLPGASTEPQPVESLPEGPQQDLPSEAPDASSEAAPNPSSTDGSALANGHRSTLDGYVYCCKECEFRSQDVTHFIGHMNSEHTDFNKDPTFVCTGCSFLAKNPEGLSLHNAKCHSGEASFLWNVTKPDNHVVVEQSVPDSASSSVLAGESTTEGTE----IIITKTPIMKIMKGKAEAKKIHMLKENAPNQPGSEALPKPLAGEREVKEGDHTFINGAAPGSQASAKSTKPPPAANGPLIGTVPVLPAGIAQFLSLQQQPPVHAQHHTHQPLPTSKTLPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASAGNVQHLIQAT--LPGHAVGQPEGTAGGLLVTQPLMANGLQASSSSLPLTTASVPK-PTVAPINT-------------VCSNSASAVKVVNAAQSLLTACPSITSQAFLDANIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRR----YHCRNLKGSRAMMPGEHGSVLIDSVPEVPFPLASKVPEVTCIPTATSLVSHPATKRQSWHQTPDFTPTKYKER----APEQLRVLENSFAQNPLPPEEELDRLRSETKMTRREIDGWFSERRKKVNTEETKKADGHMPKEEEEGAEQEGRDEELANELRVPGEN---GSPEMFLSHALAERKVSPIKINLKNLRVTEASGKSEFP--GMGVCEPEEDGLNKLVEQPPSKVSYKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALK-------------NGQLKWYEDYKRGNFPPGLLVIAPGN----RELLQDYYMTHKMLCEEDLQTLCDKTQMSAQQVKQWFAEKMGEETRAVADISS------EDQGPRNGEPVAVHKVLGDAYSELSENSESWEPSAPEASSEPFDTSSPQSGRQLEAD------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4I2-1", "uniprot_id": "ZHX3_HUMAN", "id": "Q9H4I2-1", "name": "Zinc fingers and homeoboxes protein 3", "aln": "MASKRKSTTPCMIPVKTVVLQDASMEAQPAETLPEGPQQDLPPEASAASSEAAQNPSSTDGSTLANGHRSTLDGYLYSCKYCDFRSHDMTQFVGHMNSEHTDFNKDPTFVCSGCSFLAKTPEGLSLHNATCHSGEASFVWNVAKPDNHVVVEQSIPESTSTPDLAGEPSAEGADGQAEIIITKTPIMKIMKGKAEAKKIHTLKENVPSQPVGEALPKLSTGEMEVREGDHSFINGAVPVSQASASSAKNPHAANGPLIGTVPVLPAGIAQFLSLQQQPPVHAQHHVHQPLPTAKALPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASAGNVQHLIQAA--LPGHVVGQPEGTGGGLLVTQPLMANGLQATSSPLPLTVTSVPKQPGVAPINT-------------VCSNTTSAVKVVNAAQSLLTACPSITSQAFLDASIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRR----YHCRNLKGSRAMIPGDHSSIIIDSVPEVSFSPSSKVPEVTCIPTTATLATHPSAKRQSWHQTPDFTPTKYKER----APEQLRALESSFAQNPLPLDEELDRLRSETKMTRREIDSWFSERRKKVNAEETKKAEENASQEEEEAAEDEGGEEDLASELRVSGEN---GSLEMPSSHILAERKVSPIKINLKNLRVTEANGRNEIP--GLGACDPEDDESNKLAEQLPGKVSCKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALK-------------NGQLKWYEDYKRGNFPPGLLVIAPGN----RELLQDYYMTHKMLYEEDLQNLCDKTQMSSQQVKQWFAEKMGEETRAVADTGS------EDQGPGTGELTAVHKGMGDTYSEVSENSESWEPRVPEASSEPFDTSSPQAGRQLETD------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RM49-1", "uniprot_id": "A0A8M1RM49_DANRE", "id": "A0A8M1RM49-1", "name": "", "aln": "MASKRKSTVPCMIPSKSKHMREDIILGCLPELLP-----TIPEDSILSISSKDEDAQRFHDLSKAVTKTSCWERGTYTCPLCCFESRDLNLFLHHMDSCHKDFHAQPNFYCLSCKVSAVKFEGLALHNAKSHP----ELHTAHKRVSLQVTKRDGAITVEQSLFTEEDFSESGIS-----ITKTPIMKMTKGGHKKIVVSHTVEVHRAEPS--------------IDKPATVTNGTSVRTFPLTTSTHIIGGTGAPPIYKIPNIPR-------MHNRGPLWNSN--MSSADSNADLPKVMIPLSSIPTYDPAMDLSSFLKTSFGKFPYPTKAELCYLTVVSGFPEEQIKLWFTAQRLKQGISWSPEEIEDTRRKMFNTVFQATPKTSQNQLHHNISQHCVSVQSATLSSNYIQQIPKGSAVGWKGGVIVSQPSVTQATSLKQQQPVVQAPQVNIHHAVITKETGNELSCWTTENGNNASRGGSVSNLGHTGKSETGCSSSILPGASKSQNSSYSEGSIMNLTNIVRKIDCHVNDRNANCTSKTKASPTSIYGQQKASNNTKESSFATTSKYNNGSTYKSTSHISICTKREGNILDHTSKSNTDTSVICSNSNIRTDEFLPPLTHTLVPQPGSMDLSFGKSKVLPELPGTLKQSFTHNSFPEQKRFLAPQGQPYHIHTLTDSQSALGGSFINLPQSSLQSNSAPSSHIQDEPSQHSSPPLSAPQEQHSPKTLLGAPQVQSTDITAVHYKEQDPKHLPALDKDSKQSSFDKERFYRNVTQNENEGRVSETDSGITKTFYTTDKNEHSKIVNTLHTFTNDNTNKAKQAMPLLRQYIQEVDQWESNCNHLEESNMSPMKINVISLNKDESLYKTNSKPPICKPLESLISGNDSSHKDESSAWHESLRLLPVDAEHRTTDIGNSESHQPDKLVGLETQQVKRDLCPERKSIFQSLDSEAPMLPMKKKSQEAMAELDKSTTGEQDYWEIKD-DEHQQPMGNQSLRGHQAQDSQSRDCLRGELLKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********.***** *: : * ** :* :: : *. :.. .. : * : . : * * * *.*:*:. *: ** * *.**: :* * * .*.. * . ***:****..*. : .. * . *.::. . ... . :: * :*. ********: ** : : * :* : :. **: : . :.*:: :..* * .:* :* ::: .: .: .. : **************:.*** .****.** ****************: :****:*:********************:*:******:*:.*:.: . *: : . .** :: : *.. * **::*:** :::. . ... : ...* . . :* .*. *. :: ::.:* ...** . * . . .: * :*: : .: : ::: **.: * :* .: : : :. : . .* *: . :: :.. .:.. : : :.: :. : .*: . . . ** .*:.**::*.:* ::.: :.:. : *. : . :* ::. . .... : .: . *: . . : *: :: :. * : . :* * . .. : .. : *:: . .:. :. .. ::: : : : ..:. .. *. ** :* .:..: : * : . *: .: : * : .** :: . :: : ::* : : : : .::* .: .. : : .* :. . :.:.* .: :.: : :.: ** : .:*:...* :. : ::: ", "identical_positions": 201, "similar_positions": 326, "identity": "19.73%" }, { "cls_id": "homologset.agr.MGI:2444773", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VCF0-1", "uniprot_id": "MAVS_MOUSE", "id": "Q8VCF0-1", "name": "Mitochondrial antiviral-signaling protein", "aln": "MTFAEDKTYKYIRDNHSKFCCVDVLEILPYLSCLTASDQDRLRASYRQIGNRDTLWGLFNNLQRRPGWVEVFIRALQICELPGLADQVTRVYQSYLPPGTSLRSLEPLQLPDFPAAVSGPSAFAPGHNIPDHGLRET-PSCPKPVQDTQPPESPVENSEQLLQTNSG-AVARMS-GGSLIPSPNQQALSPQPSREHQEQEPELGGAHAANVASVPIATYGPVSPTVSFQPLPRTALRTNLLSGVTVSALSADTSLSSSSTGSAFAKGAG-------DQAKAATCFST------TLTNSVTTSSVPS--------PRLVPVKTMSSKLPLSSKSTAAMTSTVLTNTAPSKLPSNSVYAGTVPSRVPAS--VAKAPANTIPPERNSKQAKETPEGPATKVTTGGNQTGPNSSIRSLHSGPEMSKPGVLVSQLD-EPFSACSVDLAISPSSSLVSEPNHGPEENEYSS---FRIQVDESPSADLL-----------GSPEPLATQQPQEEEEHCASSMPWAKWLG-ATSALLAVFLAVMLYRSRRLAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HG9-1", "uniprot_id": "MAVS_RAT", "id": "Q66HG9-1", "name": "Mitochondrial antiviral-signaling protein", "aln": "MTFAEEKTYKYIRYNHSKFCCVDVLEILPYLSCLTTSDQDRLRASYKQLGNQGTLWELFNTLQRRPGWVEVFIRALRICELPGLAEQVTRVYQSYLPPGASLHSLDPLQSPRIPTTVSEPSAFAAGHTIPDSGFQDK-PGYPKPVQDTQPPKSPVENSEEPPQANFG-AIPRMS-GDSLISSPNPPALSPQPSREHPEQEPELGGPSTANVDSVPIATYGPVSPTVSFQPLPRIAPRTNLSPGVTVSALSAKTTLSSSSTGSAFAKGAG-------DQAKAATCVSTKEG---VPTNSVTTSSVPS--------IKPVPVNTMSSKLPISTKSTAATPSTVPTNIAPSKLPINSVYTGIVPSKVTAS--VAKASASTMPPERNNKQAKETLEAPATVVTTGSSLTRPDISSRSLHSGPELSKPGVLVSQVDNEPFSACSMDLAISPSTSLGSEPNHGPEENEYSS---FRIQVDKSPSVDLL-----------GSPEPLATQQSPEEEEPCASSVSWAKWLG-ATSALLAAFLAVMLYRSRHLAQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z434-1", "uniprot_id": "MAVS_HUMAN", "id": "Q7Z434-1", "name": "Mitochondrial antiviral-signaling protein", "aln": "MPFAEDKTYKYICRNFSNFCNVDVVEILPYLPCLTARDQDRLRATCTLSGNRDTLWHLFNTLQRRPGWVEYFIAALRGCELVDLADEVASVYQSYQPR-TSDRPPDPLEPPSLPAERPGPPTPAAAHSIPYNSCREKEPSYPMPVQETQAPESPGENSEQALQTLSPRAIPRNPDGGPLESSSDLAALSPLTSSGHQEQDTELGSTHTAGATSSLTPSRGPVSPSVSFQPLARSTPRASRLPGPTGSVVSTGTSFSSSSPGLASAGAAEGKQGAESDQAEPIICSSGAEAPANSLPSKVPTTLMPVNTVALKVPANPASVSTVPSKLPTSSKPPGAVPSNALTNPAPSKLPINSTRAGMVPSKVPTSMVLTKVSASTVPTDGSSR-NEETPAAPTPAGATGGSSAWLDSSSENRGLGSELSKPGVLASQVD-SPFSGCFEDLAISASTSLGMGPCHGPEENEYKSEGTFGIHVAENPSIQLLEGNPGPPADPDGGPRPQADRKFQEREVPCHRPSPGALWLQVAVTGVLVVTLLVVLYR-RRLH-", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.***:****** *.*:** ***:******.***: *******: **:.*** ***.********* ** **: *** .**::*: ***** * :* :. :**: * :*: . *.: *..*.** . ::. *. * ***:**.*:** ****: *: *:.* . *..* .*.: **** .* * **:.***.. :*.. * .: *****:******.* : *:. .* * *.:*: *::****.* * * .* ***:. * * ...*.*: :* . ..*.*:.**** *:*...* .*.. ** ****** **. :* ***:*.:* ::*..*.*:*.: ..: :** .*:. :**.. : : * .. *.*:******.**:* .***.* *****.*:** * ********.* * *:* :.** :** *.*.* * :: *.* * . . * ** *.:.:*.. * *:*** *:* ", "identical_positions": 238, "similar_positions": 146, "identity": "43.67%" }, { "cls_id": "homologset.agr.MGI:2444776", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMZ8-1", "uniprot_id": "D3ZMZ8_RAT", "id": "D3ZMZ8-1", "name": "", "aln": "---------------------------MAQGPSQCPALLGAPASTTDGTQEARVPLDGAFWIPRPPAGSPKGCFACVSKPPALQAAAAPAPEPSASPPMAPTLFPMESKSSKTDSVRASGVPQACKHLAEKKTMTNPTTVIEVYPDTTEVNDYYLWSIFNFVYLNFCCLGFIALAYSLKVRDKKLLNDLNGAVEDAKTARLFNITSSALAASCIILIFIFLRYPLTDY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BR26-1", "uniprot_id": "IFM10_MOUSE", "id": "Q8BR26-1", "name": "Interferon-induced transmembrane protein 10", "aln": "---------------------------MAQGPSQCPALLGAPASTTDGTQEARVPLDGAFWIPRPPAGSPKGCFACVSKPPALQAAAAPAPEPSASPPMAPTLFPMESKSSKTDSVRASGVPQACKHLAEKKTMTNPTTVIEVYPDTTEVNDYYLWSIFNFVYLNFCCLGFIALAYSLKVRDKKLLNDLNGAVEDAKTARLFNITSSALAASCIILIFIFLRYPLTDY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NMD0-1", "uniprot_id": "IFM10_HUMAN", "id": "A6NMD0-1", "name": "Interferon-induced transmembrane protein 10", "aln": "MREGKRGPPCILSFRGTLERVEAQWELEAQGPGQCPAPLGDPASTTDGAQEARVPLDGAFWIPRPPAGSPKGCFACVSKPPALQAPAAPAPEPSASPPMAPTLFPMESKSSKTDSVRAAGAPPACKHLAEKKTMTNPTTVIEVYPDTTEVNDYYLWSIFNFVYLNFCCLGFIALAYSLKVRDKKLLNDLNGAVEDAKTARLFNITSSALAASCIILVFIFLRYPLTDY", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****.**** ** *******:************************************.********************************:*.* *********************************************************************************************:***********", "identical_positions": 191, "similar_positions": 6, "identity": "83.77%" }, { "cls_id": "homologset.agr.MGI:2444777", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZVL6-1", "uniprot_id": "A0A8I5ZVL6_RAT", "id": "A0A8I5ZVL6-1", "name": "Condensin complex subunit 2", "aln": "MQKFATEEAWALELETGGSEIQEKMNNSSLKTRGQQDIVSSPSERVLSVSRPAKAPLSTPKTPVLEDFPQNDDEKERMQRRRSRVIDLQFSTDS-IHLASPN-RNIDVSAPIPKFTNTQITEHYSTCIKLSTENKITTKNAFGLHLIDFMSEILKQKDTEP-TNFKVAAGTLDASTKIYAVRVDAVHADVYRVLGGLG----KDTPPQEGEESHSGEG-----------------SAVETERTKKAAKPKKKQSCRTIEQNLSNIN---VSEADGKCAVDPMFQKTAASFDECSTAGVFLSTLHCQDYRSELLFPSDMQALSSGE-PLELPDLGFVDMTDLKAPLQQCAEDRQLCPSLAGFQFTKWDSETHNESVSALVDKFKKNDQVFDINAEVEDDDE-DVPDGP------------LVEDFVDNDEPDPCAAGDQEE------FRSWKEICQVPGSQEEIVSLG-DRDIQTMCSFLSTKPGEYSYFS--PRTMKMWAGPDHWRFR--------------------------PRPKQNTASCTENKKKSTKKDFEIN-FDDDIDFDAYFQKTKVATILTKSTLENQNW-KATTLPADFLYETDNLVQLHLKPDIRSLKMSQSQKAKTEHYEEIEDYDYNNPNDTSNYCPGLQDAD--------SDYEESDGLFAGPVGTLDLE----SDPKTAQENGHISPESQGVDITTYGESNLVAEPQK-----VNKIEIHYAKTAKKMDMKKLKQTMWSLLTEFSRKETDIEAN--HTDNGKEEAPEEVADEKKLSGLTKDLQTRLPPLMAQNLSIPLAFACLLHLANEKNLKLEGTEDLSDVRVMQGD--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C156-1", "uniprot_id": "CND2_MOUSE", "id": "Q8C156-1", "name": "Condensin complex subunit 2", "aln": "-------------MRIPRS---ETMNSSFLKARGQQDVLSSPLERVPPASRPGKAPLGTPKTPVLEDFPQNDDEKERMQRRRSRVFDLQFSTDS-IHLASPN-RNIDVSTTISKFTNTQITEHYSTCIKLSSENKITTKNAFGLHLIDFMSEILKQKDAEP-TNFKVAAGTLDASTKIYAVRVDAVHADVYRVLGGLG----KDTPPQ-GEESHSGDG-----------------STLETERTKKPAKPKKKQSCKTIEQNLSNIN---VSEADGKCAVDPMFQKTAASFDECSTTGVFLSTLHCQDYRSELLFPSDMQTLSSGE-PLELPDLGFVDMTDLEASLQQCVEDRPLCPSLAGFQFTKWDSETHNESVSALVDKFKKNDQVFDINAEAEDDEE-DVPDGP------------LVEDFVDNDEPDLSAAGDHEE------FRSWKELCQVQSNQEEVISLE-DRDIQVMCSFLSMKPGEYSYFS--PRTMKMWAGPDHWRFR--------------------------PRPKQDATSCTEHKKKSAKKDFEIN-FDDDIDFDAYFQKTKAATILTKSTLENQNW-KATTLPTDFHYETDNLIQLHLKPGKRSLKMDQDQKAKTEHYEEIEDYDYNNPNDTSNYCPGLQAAD--------SDYEEADDLFADPVGTLDLE----SDPKTTQENGHISPENQGVDITTYQELNLVAEPQK-----VNKIEIHYAKTAKKMDMKKLKQSMWSLLTKFSRKEADTEAN--HTESGQEGAPEEVADEKKLSGLTKDLQTRLPPLMAQNLSIPLAFACLLHLANEKNLKLEGTEDLSDVLVMQGD--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15003-1", "uniprot_id": "CND2_HUMAN", "id": "Q15003-1", "name": "Condensin complex subunit 2", "aln": "-------------MGPPGPALPATMNNSSSETRGHPHSASSPSERVFPMPLPRKAPLNIPGTPVLEDFPQNDDEKERLQRRRSRVFDLQFSTDSPRLLASPSSRSIDISATIPKFTNTQITEHYSTCIKLSTENKITTKNAFGLHLIDFMSEILKQKDTEP-TNFKVAAGTLDASTKIYAVRVDAVHADVYRVLGGLG----KDAPSLEEVEGHVADG-----------------SATEMGTTKKAVKPKKKHLHRTIEQNINNLN---VSEADRKCEIDPMFQKTAASFDECSTAGVFLSTLHCQDYRSELLFPSDVQTLSTGE-PLELPELGCVEMTDLKAPLQQCAEDRQICPSLAGFQFTQWDSETHNESVSALVDKFKKNDQVFDINAEVDESDCGDFPDGS------------LGDDFDANDEPDHTAVGDHEE------FRSWKEPCQVQSCQEEMISLG-DGDIRTMCPLLSMKPGEYSYFS--PRTMSMWAGPDHWRFR--------------------------PRRKQDAPSQSENKKKSTKKDFEID-FEDDIDFDVYFRKTKAATILTKSTLENQNW-RATTLPTDFNYNVDTLVQLHLKPGTRLLKMAQGHRVETEHYEEIEDYDYNNPNDTSNFCPGLQAAD--------SDDEDLDDLFVGPVGNSDLSPYPCHPPKTAQQNGDT-PEAQGLDITTYGESNLVAEPQK-----VNKIEIHYAKTAKKMDMKKLKQSMWSLLTALSGKEADAEAN--HREAGKEAALAEVADEKMLSGLTKDLQRSLPPVMAQNLSIPLAFACLLHLANEKNLKLEGTEDLSDVLVRQGD--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38170-1", "uniprot_id": "CND2_YEAST", "id": "P38170-1", "name": "Condensin complex subunit 2", "aln": "-------------------------------------------------------------MTTQLRYENNDDDER---------VEYNLFTNR-----------------------STMMANFEEWIKMATDNKINSRNSWNFALIDYFYDLDVLKDGENNINFQKASATLDGCIKIYSSRVDSVTTETGKLLSGLAQ--RKTNGASNGDDSNGGNGEGLGGDSDEANIEIDPLTGMPISNDPDVNNTRRRVYNRVLETTLVEFETIKMKELDQELIIDPLFKKALVDFDEGGAKSLLLNTLNIDNTARVIFDASIKDTQNVGQGKLQRKEEELIERDSLVDDENEPSQSLISTRNDSTVNDSVISAPSMEDEILSLGMDFIKFDQIAVCEISGSIEQLRNVVEDINQAKDFIENVNNRFDNFLTEEELQAAVPDNAEDDSDGFDMGMQQELCYPDENHDNTSHDEQDDDNVNSTTGSIFEKDLMAYFD--ENLNRNWRGREHWKVRNFKKANLVNKESDLLEETRTTIGDTTDKNTTDDKSMDTKKKHKQKKVLEIDFFKTDDSFEDKVFASKGRTKIDMPIKNRKND-THYLLPDDFHFSTDRITRLFIKPGQKMSLFSHRKHTRGDVSSGLFEKSTVSANHSNNDIPTIADEHFWADNYERKEQEEKEKEQSKEVGDVVGG-ALDNPFEDDMDGVDFNQAFEGTDDNEEASVKLDLQDDEDHKFPIRENKVTYSRVSKKVDVRRLKKNVWRSINNLIQEHDSRKNREQSSNDSETHTEDESTKELKFSDIIQGISKMYSDDTLKDISTSFCFICLLHLANEHGLQITHTENYNDLIVNYEDLATTQAAS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VIP9-1", "uniprot_id": "Q9VIP9_DROME", "id": "Q9VIP9-1", "name": "Condensin complex subunit 2", "aln": "-----------------------------------------MTLPRLETPLRRSAVGSYQEGVSRMLTPFNDDEAERREARRRTLLQQHHRSST--------------------LESIEDNETIKNCLELYNGNKVSKDNAWNLMLIDSLANLLDHHHKRM-SNFKMAGSSLEASSKVYGLRVDSIYLDAMRISAGLSARTLTDKQINAAEDDDGPQGEQATGEGQD--------SAQQAAKEAAPKPKRQKKPISTVTKNRETLN----SRLDTAPLQDPVFGKLNSTVGSINASNRLMHNILPS-FDSELRLRTTYNFWNSEESTEEVQDHTTLNAEMEQWPATSLMSTNLMRKLLPHAERSNLRPLHTGYIITSAPNPKSANEKAAEVVQDEDHDEGLDNADDMCVN------EISMAFDINAECEPMPDLDGPPPLVLEVDSNELEELTAEEQMVINNCRRLRKQTEFIEDLRPVDGNSKLEYSYRPMDQISQFWAGPSHWKFKRTRPRSTFSQTNG-------------QVDTQPIRTQRAKKSAHLNANRRAKALDYGNVTENFFQQLDTTIRQRKANFQKKWDPRKLILPTKFELDPDLFFKYESAPSIKLSKRAGEPDSD-EGGDLGIDMDADMHHDDDNDQELFNNEH----------FTDAVPANVSVIAAIAAEQAAEASMMNVSAGEIGLTQMNATCNNTVFEIGTEFEGAPS---QVAKVIVPFAKRAKVIDMKNLKKSCNSLIQKQLLNAVPEETIPSHPKKKGEHYSKGFAS---FQQVYQKLPDLLTTKMSDSLSPSVAFYAVLHLANDLKLRLIPQEDLEDFQIRQVLD-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***: . .: : :. . ::: . **:.. *::.: *** : :: :. . **: *..:*:.. *:*. ***:: :. :: .**. . :.. :* : ::: .: . :: .. * **:* * ... .: . :: .: . : : : . : : : :: . . . : : . : : :: . . .: : :. :: : * . : . :: : : : : . * * .**:.: . : :*. : . . :. . : . . . :.: ** .* . * : : *. : : . : . :. .* : . : :. . :. . . : : : : ::: :* :*::.**:. : : : . :. :. : : : . ..:* ...* .:*****: *:: *: .*. : ", "identical_positions": 52, "similar_positions": 194, "identity": "6.1%" }, { "cls_id": "homologset.agr.MGI:2444782", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A7U0-1", "uniprot_id": "A0A8I6A7U0_RAT", "id": "A0A8I6A7U0-1", "name": "peptidylprolyl isomerase", "aln": "----MFGAGDEDDTDFLS----PSGGAKLASLFGLDQASVGHGNEFFQYTAPKQPKKGQGIAATGNQSAPKPAPATTGTSSVLFATAVHAYRCINGQYAKQGKFGAAVLGNHTTREYRILLYISQQQPVTVATIHLNFELMVRPNNYSTFYDDQRQNWSIMFESEKAAVAFNKQVCVAKCNSISSLDAVLCQDLVAAEGPAVETGDSLEVAYTGWLLQNHVLGQVFDSTANKDKPLRLKLGSGKVVKGLEDGLLGMKKGGKRLIITPSACAAASEGVIGWTQPTDSILVFEVEVRRVKFARDSGSDGHSVSSRDSAAPSPIP---AADSLSADPVVTPPLPLPLKPGE---PALRSKSSSVSEPLTVSTSPDTAKAKLISRMAKMGQPMLPILPP------QLDSNDSETEDATLLRGAGPSLVTPSVQPSLQPSHPVLPQMASQAPQPAVSGLQTASAALMPAVSLDSHSAVSGNAQNFQPYAGVQAYTYPQTSSVSSQLQPARPLYPAPLSQAPHFQGSGDMMSFLMTEARQHNTEIRMAVNKVADKMDHLMTKVEELQKHSTGNSMLLPSMSVTMETSMIMNNIQRIIQ-ENERLKQELLEKSSRIEEQNDKISDLIERNQRYVEQSNLMMEKRNNSLQTATENTQARILHAEQEK-----------AKVTEELAAATAQVSHLQLKMTAHQKKETELQLQLTENLKETDLLRGQVTRLQADLLELREASEQTQTKFKSEKQSRRQLELKVTSLEEELTDLRAEKESLEKNLSERKKKSAQERCQAEEEMDEIRKSHQEELDRLRQLLKKARVSTDQAAAEQLSLAQAELKSQWEAKCEHLLATAKDEHLQQYQEVCAQRDAYQQKLSHVQDECLALQAQIAAFTQQNE-HMQRLEKSKSQAP----------------------------AGRAAADPSEKVKKIMNQVFQSLRGEFELEESYDGRTILRTIMHTIKMVTLQLLNHQEEEQGECSSEEEKE---EKPLRPSLEQPGPATPRTPLALPSEEPQEAPKVLSEQVEGETTPLPLQALPMPENGAQTRKGEPSEPEVSSEIKDSSLPPEPAGFPAHRVLGPPTSIPPKPPGPVTIDSESEETVAAGQRTLQPNSLLEEEHVREVATDGLLQGNPRRLSLTPDPEKKEPPALDPESQE-EPQPPVLKQAKDISSSGP-CEVMDTERAAADTGASPRHSQDSQHCSVSGDEEDELFKGATLKVPRPTAQPEEEDEDEVSMKGRPPPTPLFGDDDDDDD--IGWLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P9Q6-1", "uniprot_id": "FKB15_MOUSE", "id": "Q6P9Q6-1", "name": "FK506-binding protein 15", "aln": "----MFGAGDEDDTDFLS----PSGGAKLASLFGLDQATMGHGNEFFQYTAPKQPKKGQGTAA-GNQTAPKPAPATTGTSSVLFATAVHAYRYINGQYAKQGKFGAAVLGNHTSREYRILLYISQQQPVTVATIHLNFELMVRPNNYSTFYDDQRQNWSIMFESEKAAVSFNKQVCVAKCNSISSLDAVLCQDLVAAEGPAVETGDSLEVAYTGWLLQNHVLGQVFDSTANKDKPLRLKLGSGKVVKGLEDGLLGMKKGGKRLIITPSACAAGSEGVIGWTQPTDSILVFEVEVRRVKFARDSGSDGHSVSSRDSAAPSPIP---ASDSLSADPVVTP-LPLPLKPGE---PGLRSKSNSLSEQLTVNSNPDTVKAKLISRMAKMGQPMLPILPP------QLDSNDSETEDATVLRGAGQSLVTPSIQPSLQPAHPVLPQMASQAPQPSGSGLQTPSAALMQAVSLDSHSAVSGNAQNFQPYAGVQAYAYPQTPSVTSQLQPVRPLYPAPLSQAPHFQGSGDMMSFLMTEARQHNTEIRMAVNKVADKMDHLMTKVEELQKHSSGNSMLLPSMSVTMETSMIMSNIQRIIQ-ENERLKQELLEKSSRIEEQNDKISDLIERNQRYVEQSNLMMEKRNNSLQTATENTQARILHAEQEK-----------AKVTEELAAATAQVSHLQLKMTAHQKKETELQLQLTDNLKETDLLRGHVTRLQADLSELREASEQTQTKFKSEKQSRRQLELKVTSLEEELTDLRAEKTSLEKNLSERKKKSAQERCQAEAEMDEIRKSHQEELDRLRQLLKKARVSTDQAAAEQLTLAQAELQSQWEAKCEQLLASARDEHLQQYREVCAQRDAHQQKLALLQDECLALQAQIAAFTEQKE-HMQRLEKTKSQAP----------------------------AGRAAADPSEKVKKIMNQVFQSLRGEFELEESYDGGTILRTIMHTIKMVTLQLLNHQEEEE-EEEEEEEEE---KKPLRPSLEQPGPATPGMPPAPPSGETQEAPEVLPEQVVGETTPLPLQALPTPENGAQTRKGEPAEAEVPSEIKDSSLPPQPAGIPAHRVLGPPTSIPPKPPGPVTMDSESEEMLAADQRTVQPNGLLGEEHVREVATDGLLQGNSRRLSLTPDPEKGEPPALDPESQGGEAQPPECKQAEDVSSSGPRETLLDTELASAAAGTSLRHNQDSQHCSLSGDEEDELFKGATLKVPRPTAQPEEEDEDEVSMKGRPPPTPLFGDDDDDDDDDIGWLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T1M5-1", "uniprot_id": "FKB15_HUMAN", "id": "Q5T1M5-1", "name": "FK506-binding protein 15", "aln": "----MFGAGDEDDTDFLS----PSGGARLASLFGLDQAAAGHGNEFFQYTAPKQPKKGQGTAATGNQATPKTAPATMSTPTILVATAVHAYRYTNGQYVKQGKFGAAVLGNHTAREYRILLYISQQQPVTVARIHVNFELMVRPNNYSTFYDDQRQNWSIMFESEKAAVEFNKQVCIAKCNSTSSLDAVLSQDLIVADGPAVEVGDSLEVAYTGWLFQNHVLGQVFDSTANKDKLLRLKLGSGKVIKGWEDGMLGMKKGGKRLLIVPPACAVGSEGVIGWTQATDSILVFEVEVRRVKFARDSGSDGHSVSSRDSAAPSPIP---GADNLSADPVVSPPTSIPFKSGE---PALRTKSNSLSEQLAINTSPDAVKAKLISRMAKMGQPMLPILPP------QLDSNDSEIEDVNTLQGGGQPVVTPSVQPSLHPAHPALPQMTSQAPQPSVTGLQAPSAALMQVSSLDSHSAVSGNAQSFQPYAGMQAYAYPQASAVTSQLQPVRPLYPAPLSQPPHFQGSGDMASFLMTEARQHNTEIRMAVSKVADKMDHLMTKVEELQKHSAGNSMLIPSMSVTMETSMIMSNIQRIIQ-ENERLKQEILEKSNRIEEQNDKISELIERNQRYVEQSNLMMEKRNNSLQTATENTQARVLHAEQEK-----------AKVTEELAAATAQVSHLQLKMTAHQKKETELQMQLTESLKETDLLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEEELTDLRVEKESLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDKLRQLLKKTRVSTDQAAAEQLSLVQAELQTQWEAKCEHLLASAKDEHLQQYQEVCAQRDAYQQKLVQLQEKCLALQAQITALTKQNEQHIKELEKNKSQMSG---------------------------VEAAASDPSEKVKKIMNQVFQSLRREFELEESYNGRTILGTIMNTIKMVTLQLLNQQEQEKEESSSEEEEEKAEERPRRPSQEQSASASSGQPQAPLNRERPESPMVPSEQVVEEAVPLPPQALTTSQDGHR-RKGD-SEAEALSEIKDGSLPPELSCIPSHRVLGPPTSIPPEPLGPVSMDSECEESLAASPMAAKPDNPSGKVCVREVAPDGPLQESSTRLSLTSDPEEGDPLALGPESPG-EPQPPQLKKDDVTSSTGPHKELSSTEAGSTVAGAALRPSHHSQRSSLSGDEEDELFKGATLKALRPKAQPEEEDEDEVSMKGRPPPTPLFGDDDDDDD--IDWLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXU5-1", "uniprot_id": "A0A8M9PXU5_DANRE", "id": "A0A8M9PXU5-1", "name": "peptidylprolyl isomerase", "aln": "MEKIRDVIPDYHDGDFLC----PKSGAKLASLFGLDRAEC-QGNESFQFTAPKQPKRTSGVLG---LPPKKPPPPPPCAPAVLFATAAHAFCFVNGQYVKQGKIGAAVLGNHVTKEYKILLYGNKQKQITTARIQRGFVLTVQPCEYVAFYDDQQQNWSLMFDLEKARPEFIREVFLARWNSEASSDSLLTQDLLHGEGQAVNVGDTVEVAYSAWLLHNHSLGQIFDSNLGKEKLQRVKLGSGKALRGLEDGVLGMQKGGRRLLIIPPSMSYGSKSGP-NHVPAESTLVYDVEIHRVKFCKNRHGG-------GSAEPSRTPPDICSDTLSEGKLDTPETDKSKCAQHDLDQAPDGKVEPKSECQID---SGPSKAKLISRIAKMGQPMLPFLIG--AIPAQPDPSDSETEDASESG------LTCDPCPSHDSPSPKPAQIPCTSPP-------SLYQADAVQNKEAAPQAESNPAQDFQPCSCRENPYFPP------QLNSFTSIYQA---QHIPYS-TPDITSFLMSDARQHNKEILMAIEKLEHRVDRLTSKVDDLHKEG---HFSFGLATVSLETNMILYNIQRIIQQESVCLKNEVL--SSKLEGQNHKMEDLCEQNKRYMEQ----------------LPIQTCHIHSEQEK--------------EDSLISS----CQLQQQLVNLQQRETEIQTQLSAALDDKHKHCAQISLLEAQVAELLKKEEQSDQRWRAEKQKYKELESTIQNMDEEMQDLRAEKENLQQVLSEKKRKWKAERERIIVEQEEEHERSQQEVLQLLMQLRKARHSTEALMK------QAEFELSAQKKCD--------------AELAEQ-EKLEGAITELQEQCEDLTTTSSSMN-----------------------------------------------EQFDTQLAVQVKRAMKEVFQCLRTEFDLQESYRGHSVLQILQNTIKGVTMKFLSES----WEFESDED--------------------------KAEEEYGSTEEVLMPKDNDE-------------------------IEEKVEH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0R4IUL0-1", "uniprot_id": "A0A0R4IUL0_DANRE", "id": "A0A0R4IUL0-1", "name": "peptidylprolyl isomerase", "aln": "-----MFGADDEDGDFLS----PGGGAKLASLFGLDQATS-QGNESFQYTAPKQPRKSSGNSG---PSTQKPAPP-ANSPAVLFATAVHAHRYVNGQYVKQGKLGAAVLGNHTTKEYKILLYVSQQKQVTAAKIHSGFILTVQARNYCSFYDDQRQNWSLMFETEKAAADFSKEVCLAKVNSGGASDSVLIQDLVLGEGQAVENGDSLEVAYTGWLLQNHTTGQMFDSNLNKDKLLRLKLGAGKVIKGWEEGMLNMRKGGKRLMVIPPALAYGSQGVP-NRVPPDSTLIFEAEIRRVKFVKDVGSG-------DSASPSPAP---SVESLGPSELNQPVSSVPQSSRP-SEPPLRAKSNSLSEQLTN---PDATKAKLISRMAKMGQPMLPFITGPASSPSQPDSSDSELEDPSVSR------LKERSS----APSPQPLHISSAPPP-------ALQTAALLPVSMAAANP-----QPMMPAAIH-------------AFQPVSQMYPT---QTVPYQGTSDVTSFLMTEARQHNTEIRLAVGKVADKLDTLSSRIDDLQKQS---SVSMGLSNVSMETAMIMHNIQRIIQ-ENECLKKEVFEKSSRIEEQNRKISELIDQNQRYVEQRNLLMEQRNDSLKNSSEQNQARRLQAEQDKHALPKELSWDQARLTEDLASSTARVSELQLELSSQQQKLSTLQSKLSAALQDNQQHCTQITALDAQILELKETAERAQSQYKTEKQKRKELELKLNNQEEELQDMKTEKDSLERTLSERKRKWQAERQRCDEELEELRRAGQQEMENLRSQLRRARTSTDHAAAQQLSQLQVDLEREWQVKCDQAVAAAREQQRRETAELSEHRDTLQSKLTQLQEKFNALKKSRESEDQRLLQQQDQSEELQAFREKCCLLEQRVVMLKQQEETRVSELETRLTEQQQQTDTAGEVKRVMNGVFQSLRGEFDLNETYTGSAVLRVLVNTIKNVTLQLLTKAERSSSEHEEEEEDR-------DDEEERPDKLQINGQREEEEEDEREPEEIQMKEEEEEEHTSPAEEKKTED--TEESKGEQESAEEKIEENASTEDMKADQINPNSAENTLQDQLNASAENTLLDQSTENTLVDEFNESSTENTLLAETERDLTAREEVTSELPDVTGPAQEVTVMDESVSGHLDEAETTETMLFGGPPKNPPPPPAALQDKCADTPEVTHSSSERVEEENGEEPFFQSPVPPASTPVSTPAPTEAAADEEEEELSLKGRPPPAPLFGDDSDEED--LDWLG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3Z4-1", "uniprot_id": "Q9W3Z4_DROME", "id": "Q9W3Z4-1", "name": "", "aln": "----MEIGNDQSYQDFFDKLRSESGPRNLRQIFEDDDRPLANESSSLRYQPGSSKKLQAGKRP---AMTRSSTQETGDSPPAAWNTAIAKVVHAYRSSENVGRVGLALSILGEMEASKLIVYRSKSQVLTTLQLTPRGGKVILRESYLQFYDDEQRFWSLRFDKEPDEKEFITFMVKNKLP------------------------------------VEHYLSEISSS-------------------------------------------------------------------------------------SSASPSRED----LSKIRTKATVTKTTPNPPQPQP---------------------------------RSRVTLPTLEKADD---------------------------------------------------------------------------------------------------------------------------------------EERERETETPSNEDVIVTPVPRPIGSSNAHRKLSAS-SLAVANASTSSDTPLAVTTLDKYLD----------------------------------------------------------------------------------------------------EQRASGALMEHKMDAILQAMNRMGGQSS---------------VAPKKPSDPLLERDSEDEMLELEQKLLNLKRENRALMRNLKAREQALEDLRCSACALCEELLVQNGELKSQNAQLLLASQHISDSSTAAS-------------------------------PAHCRNCESSSRQIAKMQLHISALQEALRIFQ-------------------------------------------------KSGDSSSSSGRL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **: . .* .:* * : .. ::: . .. : * . ... :.. ** . : *:.* *: . ::::* .:.: :*. : : .* ****::: **: *: * * : : :* .:: .* .** ** ..: . . ::: * * : *:::.* : : : :* . . . ..: :* : : .::: :: : : :: :: *. . : : : :: :: * : . :::: ::: *: * : *. ::: * :* : . * :: :: . : : . : :* . * : : . : ", "identical_positions": 46, "similar_positions": 134, "identity": "3.59%" }, { "cls_id": "homologset.agr.MGI:2444783", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJP6-1", "uniprot_id": "RRF2M_RAT", "id": "Q5BJP6-1", "name": "Ribosome-releasing factor 2, mitochondrial", "aln": "MFTNWRIFAVNRQKTFSVHIHTTCYCKIKANLKRSKTQVPLTRSYSSPPGIVGNEVKSLHSIINPPVAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTLDWKG-YRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHKIPRICFLNKMDKTGASFNYAVESIREKLKA----------KPLILQLPIGEARTFQGVVDVVNREKLIWNSD--SDDGKDFERKPLSEASDPTLLKETVEARNSLIEQVADLDDEFADLVLGEFSEDFDLVPAEKLQAAIHRVTLAQAAVPVLCGSALKNKGVQPLLDAVTTYLPSPEEREH-----------------GFLQWYKGDLCALAFKVLHDKQRGPLVFLRIYSGTLTPQSAVHNVNRNCTERMSRLLLPFADQHVEIPSLTAGNIALTVGLKQTATGDTIVSSKSSALAAARR------AGK-GERKPGRISEAESVLLAGVEIPEPVFFCTIEPPSAAKQPDLDHALEHLQREDPSLKVKLDPDSGQTVLCGMGELHIEIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRVLGDKRHFARAELEVRPAEEP--CGVAT-----IEYADSVGEDMLQAPREDIENAIHSACLQGPLLGSPIQDVAVTLHSLMIHPGTSTT----------MVTACISRCVQKALKKADKQVLEPLMSLEVTVSREYLSPVLADLA-QRRGNIQEIQTRQD--------------------------------------------NKVVLGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMSPQDQRTLLSQRSGLARVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2Q4-1", "uniprot_id": "RRF2M_MOUSE", "id": "Q8R2Q4-1", "name": "Ribosome-releasing factor 2, mitochondrial", "aln": "MFTKWRIFAVNHQRTFSVHLNTMCYCKIKANLKRLKTQLPLTRNYSSAPGIAGSDVKSLHSVINPPVAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTLDWKG-YRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHKIPRICFLNKMDKTGASFNYAVESIREKLKA----------KPLILQLPIGEARTFQGVVDVVNKEKLLWNSN--SDDGKDFERMPLSEASDRELLKETIEARNSLIEQVADLDDEFADLVLGEFSENFDLVPAEKLQAAVHRVTLAQAAVPVLCGSALKNKGVQPLLDAVTTYLPSPEERED-----------------RFLQWYEGDLCALAFKVLHDKQRGPLVFLRIYSGTLTPQLAVHNINRNCTERMSRLLLPFADQHVEIPSLTAGNIALTVGLKQTATGDTIVSSKSSALAAARR------AGR-GEREHGKKREAESLLLAGVEVPEPVFFCTIEPPSVAKQPDLDHALERLQREDPSLKVKLDPDSGQTVLCGMGELHIEIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRVLGDKRHLVSAELEVRPAEEP--CAVAK-----IEYADCVGEDLLQASREAIESAVHSACLQGPLLGSPVQDVAMTLHSLMIHPGTSTT----------MVTACISRCMQKALKKADKQVLEPLMSLEVTVSREYLSPVLADLA-QRRGNIQEIQTRQD--------------------------------------------NRVVLGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMSPQDQSALLNQRSGLAHVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969S9-1", "uniprot_id": "RRF2M_HUMAN", "id": "Q969S9-1", "name": "Ribosome-releasing factor 2, mitochondrial", "aln": "MLTNLRIFAMSHQTIPSVYINNICCYKIRASLKRLKPHVPLGRNCSSLPGLIGNDIKSLHSIINPPIAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDWKG-YRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRICFLNKMDKTGASFKYAVESIREKLKA----------KPLLLQLPIGEAKTFKGVVDVVMKEKLLWNCN--SNDGKDFERKPLLEMNDPELLKETTEARNALIEQVADLDDEFADLVLEEFSENFDLLPAEKLQTAIHRVTLAQTAVPVLCGSALKNKGIQPLLDAVTMYLPSPEERNY-----------------EFLQWYKDDLCALAFKVLHDKQRGPLVFMRIYSGTIKPQLAIHNINGNCTERISRLLLPFADQHVEIPSLTAGNIALTVGLKHTATGDTIVSSKSSALAAARR------AEREGEKKHRQNNEAERLLLAGVEIPEPVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGMGELHIEIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRTLGDKRHLVTVEVEARPIETSSVMPVIE-----FEYAESINEGLLKVSQEAIENGIHSACLQGPLLGSPIQDVAITLHSLTIHPGTSTT----------MISACVSRCVQKALKKADKQVLEPLMNLEVTVARDYLSPVLADLA-QRRGNIQEIQTRQD--------------------------------------------NKVVIGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMNPQDQNTLLNRRSGLT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0JMI9-1", "uniprot_id": "RRF2M_DANRE", "id": "A0JMI9-1", "name": "Ribosome-releasing factor 2, mitochondrial", "aln": "MLLSLTFPVLRG----------CTGHLVNRSLQAPRWRVTWKRSYS----LLQDEVKSLRTVVNPDISKIRNIGIMAHIDAGKTTTTERMLYYSGYTRALGDVDDGDTVTDYMAQERERGITIQSAAVTFDWKD-YRINLIDTPGHVDFTLEVERALRVLDGAVAVFDASAGVEAQTMTVWRQAEKHQIPCVCFLNKMDKPAASLRYSLDSIKAKLKA----------NPVLLQIPIGSGKSFTGLVDLITRQKMMWQGNALTNDGRSFEINSLQPSDDPNVLLAVSEARAALIEQVADLDDDFAELLLGEYGENFDAVPAVKLQEAVRRVTLARKGVPVLCGSSLKNKGVQPLLDAITAYLPAPNERNH-----------------DLVRWYKNDLCALAFKVVHDKQRGPLVFVRIYSGSMKAQSSVHNINRNETEKMSRLLLPFADQQIEIPSLSAGNIALTVGLKQTVTGDTIVSSKASAAAAIRR------AQAEAESR----SNSHSAALAGVEVPEPVFFCSIEPPTMAKQADLEHALNCLQREDPSLKVRIDPDSGQTVLCGMGELHIEIIHDRIKREYKIETHLGPLQVAYRETILQSATAKDLLDRILGEKRHVVSVELTVHPLKENS-SASCD-----ITFEEDVKAMLPADVREAVENGVQSAYLQGPVLGFPVQGVQTVIQNVRLESGTSAA----------MVSACVSRCMLKALKQAGGQVLEPVMALEVTVGEEHLSSVLADLS-QRRGTICDIQSRQD--------------------------------------------NKILLADVPLAEMMGYSTVLRTLTSGNATFSLELSSYEPMNSQDQNILLNKMAGLT---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCX4-1", "uniprot_id": "RRF2M_DROME", "id": "Q9VCX4-1", "name": "Ribosome-releasing factor 2, mitochondrial", "aln": "MLKYAWQSGPKQ---------------SNRWLWHLSNQI-WKRSYS---------------------SKIRNIGILAHIDAGKTTTTERMLFYAGKTRALGEVHRGNTVTDYLTQERERGITICSSAVTFSWND-HRINLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVTVWSQADKHKLPRLIFVNKMDRPDADFEKCVSDLKDKLET----------QPVCLQYPVKNEDGVLAINDVITLERLSWQQK---DLGRSYRNVKLEPSDDLRLLQE---KRNELIDQLSGLDDELADVVIS--TESFDNVDNALIERALRRATTQQKVVPVLLGSAYKNVGIQRLMDAVNAYLPAPEERN------------------QIYDCFGTEVAGKVFKIVHDKQRGPLTLVRILRGEIKRGMRLISARG-QAEVVSKLYEPLADEYREVSAVQSGDVVICAGLKSTVTGDLLTSSQSALKNAQKRYKQSLGNTAAKVEEDDELDESDELFAIDPQIPDAVYFCSIEPPSVSSQTAMEQALKQLQREDPSLRVSYDSVTGQTVLGGMGELHMDIIKSRILSEYKIDVDLGPLQIAYKETIEAPALTTLSVEKEIAGSKQSVSITLEVVKNQAELFSLDKS-----PDNLPNLNT-LRPRILQVLRKGSISALERGPRVGGQVVETQIRLHNATIGRGTADS----------FVMATAAQCVQKLLSTSGTRLLEPIMALQIVAPSERISGIMADLS-RRRALINDVLPKGER-------------------------------------------NKMILVNAPLAELSGYSSALRTISSGTASMTMQPCGFSSMNSVDESLAERRAQGLE---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39677-1", "uniprot_id": "RRF2M_YEAST", "id": "P39677-1", "name": "Ribosome-releasing factor 2, mitochondrial", "aln": "----MWKWNVRR----------WAGARVNISKNRLSVINVGSRYLS---------------TARSPLSKVRNIGIIAHIDAGKTTTTERMLYYAGISKHIGDVDTGDTITDFLEQERSRGITIQSAAISFPWRNTFAINLIDTPGHIDFTFEVIRALKVIDSCVVILDAVAGVEAQTEKVWKQSKSK--PKICFINKMDRMGASFNHTVNDLINKFMRGTTTKPVLVNIPYYRKQPTSNDYVFQGVIDVVNGKRLTWNPE--------NPDEIIVDELDGTSLEQCNRCRESMIETLTEYDEDLVQHFLEEAEGDYSKVSAQFLNASIRKLTMKNMIVPVLCGASFKNIGVQPLLDAIVNYLPSPIEAELPELNDKTVPMKYDPKVGCLVNNNKNLCIALAFKVITDPIRGKQIFIRIYSGTLNSGNTVYNSTTGEKFKLGKLLIPHAGTSQPVNILTAGQIGLLTGSTVENN---ISTGDTLITHSSKK----------DGLKSLDKKKELTLKINSIFIPPPVFGVSIEPRTLSNKKSMEEALNTLITEDPSLSISQNDETGQTVLNGMGELHLEIAKDRLVNDLKADVEFGQLMVSYKETINSETNIETYESDDGYRFSLSLLPNSDALPNCLAYPLGVNENFLIMEKNGNWDKEWKYQVSFESILNSIIASCIVGLQRGGKIANFPLYACSIKINSDWSVPPDIETPQEILKITRNLIFKALNDLKPEKYNLLEPIMNLDLTIPQSDVGTVLQDLTGARKAQILSIEDESSVSNSGASTCNSPENSNRIYIPSDAVTTLHATKDKKNTQETSSNVKKIIKAKVPLREITTYTNKLRSLSQGRGEFNIEYSDMEKVTNDRLQSILHDL-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * :*:*****:*************:*:*:* :: :*:*. *:*:**:: ***.***** *:*::: *.. . :**:*****:***:** :.* .:*. *.::*. ******* .** *:..: * : *:****: *.:. :..: *: * : * . . .: *:: ::: *: . : * * * :*: :: *:::.: .: .:. : :: :::: * . **** *:: ** *:* *:**: ***:* * : : . .**:: * ** ::** * :. : . :.:* * *. : : :*:: : .* . . : :..: : :: . : . :* .*: :*** : :.: ::.**: * ***** : : :***** ******::* :.*: : :. :* * ::*:*** . . . : : .. :: * * : . : . : . : : *. .:***:* *::. . :. :: **: *:. * .: . . :::: .** *: *:. **:::.* . : :: . . :. ", "identical_positions": 166, "similar_positions": 213, "identity": "18.91%" }, { "cls_id": "homologset.agr.MGI:2444785", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6K4-1", "uniprot_id": "G3V6K4_RAT", "id": "G3V6K4-1", "name": "DDB1- and CUL4-associated factor 5", "aln": "------------------------------MKRRAGLGG------------SMRSVVGFLSQR-GLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGGQWLVSG-DDRRVLLWHMEQAIHSRV-KPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESSETLDVFAHEDAVYGLSVSPVNDNIFASSSDDGRVLIWDIRESPHGEPFCLANYPSAFHSVMFNPVEPRLLATANSKEGVGLWDIRKPQSSLLRYGGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLPVFQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWKVPADPEAGGLGRVVNGAFMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYKQPGCTGDLDGRIEDDSRCLYTHEEYISLVLNSGSGLSHDYANQSVQEDPRMMAFFDSLVRREIEGWSSDSDSDLSESTILQLHAGVSERSGYTDSESSASLPRSPPPTVDESADNAFHLGPLRVTTTSAVVSTPATPTCEDAASRQQRLSALRRYQDKRLLALSNESDSEENVCEAELDTDLFPRPRSPSPEDGSSSSSSSTSSEDEEELNQRRANTRQRNAMRRRQKTAREERPNAPVKSTNTYIGEDNYDYPQIKVDDLSSSPNSSPERSTSTLDIQPSRAPPAANMESVERKIYKAYKWLRYSYISYSNNKDGETSLVTEEADEGRAGTSHKDNPTPSSSKEACL-TATTQRSQDQSPEGCSSDACKEGTSARNPNSGASHEHSGHPWAEVPEGTSQDANNSGSLEHSFETKKLNGKALCKALSSRAEEPSSPPVPKASGSTLNSASGNCPRTQSDDSEERSPDTVCANHNNGRLHPRPLHPHNNGQNSGELESVACSSPGHLDTDHDSPSLTGTLLHKDCCGSEMACETSTAGMREDPTDPSAMDSSKVVHGQSGLKRHRIELEDTDSENSSSEKKLKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80T85-1", "uniprot_id": "DCAF5_MOUSE", "id": "Q80T85-1", "name": "DDB1- and CUL4-associated factor 5", "aln": "------------------------------MKRRAGLGG------------SMRSVVGFLSQR-GLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHMEQAIHSRV-KPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESSETLDVFAHEDAVYGLSVSPVNDNIFASSSDDGRVLIWDIRESPHGEPFCLANYPSAFHSVMFNPVEPRLLATANSKEGVGLWDIRKPQSSLLRYGGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLPVFQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWKIPADPEAGGIGRVVNGAFMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYKQPGCTGDLDGRIEDDSRCLYTHEEYISLVLNSGSGLSHDYANQSVQEDPRMMAFFDSLVRREIEGWSSDSDSDLSESTILQLHAGVSERSGYTDSESSASLPRSPPPTVDESADNAFHLGPLRVTTTNAVASTPATPTCEDASSRQQRLSALRRYQDKRLLALSNESDSEENVCEAELDTDLFPRPRSPSPEDGSSSPSSSTSSEDEEELNQRRATTRQRNAMRRRQKTARDERPTGPAKSTNTYIGEDNYDYPQIKVDDLSPSPDSSPERSASTLDVQPSRAPPAANMESVERKIYKAYKWLRCSYISYSNNKDGETSLMAEEADEGRAGTSHKDNPTPSSSKEACL-TATAQRDQDLPSEGCSSDACKEGTSAGNPNSGAGHEHSSHPWAEVPEGTSQDTNNSGPLEHSFETKKLNGKALSKALSSRAEEPPASPGPKASGSTLNSASGNCPRTQSDDSEERSLDTVCANHNNGRLHPRPLHPHNNGQSSGELETVACSSPGHLDTDHDSPSLTGTFLHKDCCGSEMACETPSAGMREDPPDPSGLDSSKVVHGQSGLKRHRIELEDTESENSSSEKKLKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JK2-1", "uniprot_id": "DCAF5_HUMAN", "id": "Q96JK2-1", "name": "DDB1- and CUL4-associated factor 5", "aln": "------------------------------MKRRAGLGG------------SMRSVVGFLSQR-GLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHMEQAIHSRV-KPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESSETLDVFAHEDAVYGLSVSPVNDNIFASSSDDGRVLIWDIRESPHGEPFCLANYPSAFHSVMFNPVEPRLLATANSKEGVGLWDIRKPQSSLLRYGGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLPVFQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWRIPADPEAGGIGRVVNGAFMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYKQPGCTGDLDGRIEDDSRCLYTHEEYISLVLNSGSGLSHDYANQSVQEDPRMMAFFDSLVRREIEGWSSDSDSDLSESTILQLHAGVSERSGYTDSESSASLPRSPPPTVDESADNAFHLGPLRVTTTNTVASTPPTPTCEDAASRQQRLSALRRYQDKRLLALSNESDSEENVCEVELDTDLFPRPRSPSPEDESSSSSSSSSSEDEEELNERRASTWQRNAMRRRQKTTREDKPSAPIKPTNTYIGEDNYDYPQIKVDDLSSSPTSSPERSTSTLEIQPSRASPTSDIESVERKIYKAYKWLRYSYISYSNNKDGETSLVTGEADEGRAGTSHKDNPAPSSSKEACLNIAMAQRNQDLPPEGCSKDTFKEET-PRTPSNGPGHEHSSHAWAEVPEGTSQDTGNSGSVEHPFETKKLNG----KALSSRAEEPPSPPVPKASGSTLNSGSGNCPRTQSDDSEERSLETICANHNNGRLHPRPPHPHNNGQNLGELEVVAYSSPGHSDTDRDNSSLTGTLLHKDCCGSEMACETPNAGTREDPTDTPATDSSRAVHGHSGLKRQRIELEDTDSENSSSEKKLKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V9T1-1", "uniprot_id": "Q9V9T1_DROME", "id": "Q9V9T1-1", "name": "", "aln": "MREPRPLPCWRTEQNLNQSPSPFKGSISTSVQRKPGDGARKMSLWRNLRSLETRNLDVALSQRENILVAGHLPSAIFRERLSAAQNLYQRNLTGHYGCVNALEFSS-GGQFLASGGDDKRVLLWNIDRELVSKLGKPRSMNEKHASNIFCLGFDTQNSYIFSGGNDDLVIQHDLETGKILNHFSHDGPVYGLSVDRISGHLLSVATEHGEILVYDLRAG-KSEPLAIAKFKTPFNAVEFHPLNGNFLATANAKRGAMLWDLRHHQQALCQYNYIPESPSCMSVRFNCNGTLLLTLHRRLPPILYSPGAPEPVATFYHDEYFNSCTMKSCTFAGPQDELVVSGSDNFNMFIWRLEG-VDLDEKNQWMETTPVILAGHRSIVNQVRYNRERCLLASSGVEKIIKLWSPFAQQGWEGSLT---QAEALPYCTRALYR----ESSDHVSQDFSARSTDEDQVMLAFFDTLVQHELESWST-------------------------------------------------------VDNQNSSKSSTHTSTCSEASSPTE------------------------------------------EPSDEEDQDPQTDRNQNEENVQDQDIDTPNVSELSWQTYPNR----------IFYLIAKKRRSLLQLAVRGTSRHPRNVDQLLQRLIGEQKQAATQAR----------------ISDWLEETQRLFGDDELPTTSAEAAAREQRRRDGVLLCRNR----------------------------------------RTQEFKIVETPKSRITQRTRKRKLRQLIQTTKHRR---------------ATGRPRTTEMDEGSASSDTGASYDSDEEETS------------------SGDNNNNNSNERESVRTDDDGDNSSTTSLTSMEAQFSQAPSTSSSFLFHQLES------NNNSQHTSNQNHKALNGLIPDNCNTESTASTSSSM------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 238, "similar_positions": 281, "identity": "24.02%" }, { "cls_id": "homologset.agr.MGI:2444786", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9Z3-1", "uniprot_id": "D4A9Z3_RAT", "id": "D4A9Z3-1", "name": "Kelch-like protein 42", "aln": "-MSAEEMVQIRLEDRCYPVSKSKLIEQSDYFRALYRSGMREAVRPEVG-PEVQQLRGLSAPGLRLVLDFINAGGAREGWGLS-----------EDELAEASVLAEMVEAASFLQVTALLRLLLSHVRLGNCLELYRLAQVYGLPDLQDACLRFMVLRFHQVLCQPQFPLLLSPPQAPGDCSLKQRLREARMRGTPVLVALGDFLGGPLAPHPYQGEPPSMLRYEETTERWFPLANNLPPDLVNVRGYGSAILDNYLFIVGGYRITSQEISAAHSYNPTTNEWLQVASMNQKRSNFKLVAVNSKLYAIGGQAVSNVECYNPEQDAWNFVAPLPNPLAEFSACECKGKIYVIGGYTTRDRNMNILQYCPSADLWTLFETCDVHIRKQQMVSVEETIYIVGGCLHELGSN----RRSSQSEDMLTVQSYNTETRQWLYLKENTSKSGLNLTCALHNDGIYIMSRDVTLSTSLEHRVFLKYNIFADSWEAFRRFPAFGHNLLISSLYLPNKAET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFQ9-1", "uniprot_id": "KLH42_MOUSE", "id": "Q8BFQ9-1", "name": "Kelch-like protein 42", "aln": "-MSAEEMVQIRLEDRCYPVSKSKLIEQSDYFRALYRSGMREAVRPEVG-PEVQQLRGLSAPGLRLVLDFINAGGAREGWGLS-----------EDELAEASVLSEMVEAASFLQVTALLRLLLSHVRLGNCLELYRLAQVYGLPDLQDACLRFMVLRFHQVLCQPQFPLLLSPPQAPGDCSLKQRLREARMRGTPVLVALGDFLGGPLAPHPYQGEPPSMLRYEETTERWFPLANNLPPDLVNVRGYGSAILDNYLFIVGGYRITSQEISAAHSYNPITNEWLQVASMNQKRSNFKLVAVNSKLYAIGGQAVSNVECYNPEQDAWNFVAPLPNPLAEFSACECKGKIYVIGGYTTRDRNMNILQYCPSADLWTLFETCDVHIRKQQMVSVEETIYIVGGCLHELGPN----RRSSQSEDMLTVQSYNTVTRQWLYLKENTSKSGLNLTCALHNDGIYIMSRDVTLSTSLEHRVFLKYNIFADSWEAFRRFPAFGHNLLISSLYLPNKAET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2K6-1", "uniprot_id": "KLH42_HUMAN", "id": "Q9P2K6-1", "name": "Kelch-like protein 42", "aln": "-MSAEEMVQIRLEDRCYPVSKRKLIEQSDYFRALYRSGMREALSQEAGGPEVQQLRGLSAPGLRLVLDFINAGGAREGWLLGPRGEKGGGVDEDEEMDEVSLLSELVEAASFLQVTSLLQLLLSQVRLNNCLEMYRLAQVYGLPDLQEACLRFMVVHFHEVLCKPQFHLLGSPPQAPGDVSLKQRLREARMTGTPVLVALGDFLGGPLAPHPYQGEPPSMLRYEEMTERWFPLANNLPPDLVNVRGYGSAILDNYLFIVGGYRITSQEISAAHSYNPSTNEWLQVASMNQKRSNFKLVAVNSKLYAIGGQAVSNVECYNPEQDAWNFVAPLPNPLAEFSACECKGKIYVIGGYTTRDRNMNILQYCPSSDMWTLFETCDVHIRKQQMVSVEETIYIVGGCLHELGPN----RRSSQSEDMLTVQSYNTVTRQWLYLKENTSKSGLNLTCALHNDGIYIMSRDVTLSTSLEHRVFLKYNIFSDSWEAFRRFPAFGHNLLVSSLYLPNKAET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TSL1-1", "uniprot_id": "A0AB32TSL1_DANRE", "id": "A0AB32TSL1-1", "name": "", "aln": "MTSPEQIIEIVMDDKTYNVSKSKLIEKSDYFRALYSSGMRESAEDSVR------LRGLSAPGLELVLEFINTS---------------------KVQVDNETLEDLIETASFLQVTSILKLLLSEIKQENCVELFKLSEVYGMHELRRACLKFMSCYYHPMLRRPEFRMLAAN--------VREQIRDIRLKGTATLVAIGDFTHTCLD-LANQDEPWSMLRYGEVEQRWKPLASNLPQDMINVRGYGSAVLDNYLFIVGGYRMTSQEISAAHCYNPSKNEWNQVASLNQKRSNFKLLAVSGKLYAVGGHCLGTVECYSPEQDWWTCVAPLPDPLAEFSACECQGMIYVMGGYTSKDRNTNVLRYCPVSDAWSVFHSCSAHVRKQQMLSVEDTIYLVGGYTHELEARESGRRRLSQTEDMLTVQSYNVQTGEWLQLKENTSKSGLNLTCTLHNDGIYIMSRDVSLPTSQEHRVFLKYNIFSDAWEAFRRFPALGQNMLLCSLYLPNVL--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*::::* ::*: * *** ****:******** *****: .. *********.***:***:. . : . * :::*:*******::*:****.:: **:*:::*::***: :*: ***:** :* :* :*:* :* : :::::*: *: **..***:*** * . *.** ***** * :** ***.*** *::********:************:*********.*** .*** ****:*********:**..****:**:.:..****.**** *. *****:**********:* ***:****::*** *:*:*** :* *::*.:*..*:*****:***:***:*** *** .. ** **:**********. * :** **************:*************:*.** ***********:*:*********:*:*:*:.****** ", "identical_positions": 296, "similar_positions": 110, "identity": "58.04%" }, { "cls_id": "homologset.agr.MGI:2444789", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BY79-1", "uniprot_id": "S35G1_MOUSE", "id": "Q8BY79-1", "name": "Solute carrier family 35 member G1", "aln": "MGPPESAAELAAEAVELREPELQLADPASPG--EEHVDVEAEGAPGRGRCWPCGAWACGSRGEPEAKKKAP-CPGLGLFYTVLSAFLFSVASLFVKKVQG----------VHAVEISAFRCVVQMLVIIPCLIYRKT----GFIGPKGQRLFLFLRGVFGSSAMILMYYAFQTTSLADATVIAFSCPVFTSIFAWIFLKEKYSLWDAFFTLFAIAGVILIVRPPFIFGSDTSG--------MRES-YSEHIKGTFAAIGHAVLAAITLVILRKMGKSVDYFLSIWYYVILGLPEAIIILFVIG--EWSLPYCGLDRLFLILIGLLGLGGQIFITKAVQIEKAGLVAIMKTMDIVFAFIFQIAFFDNVPTWWTVGGALCVVVSTTGATIRRWLQGSK----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LVD2-1", "uniprot_id": "A0ABK0LVD2_RAT", "id": "A0ABK0LVD2-1", "name": "Solute carrier family 35 member G1", "aln": "MGPPESAAELSPEAVELREPELQLADPASPG--EEHVDVEAEGAPGRGRCWPCRAWACGSRGEPEAKKTAP-CPGLGLFYTVLSAFLFSVVSLLVKKVQG----------VHAVEISAFRCVVQMLVIIPCLIYRKT----GFIGPKGQRLFLFLRGVFGSSAMILMYYAFQTTSLADATVIAFSCPVFTSIFAWIFLKEKYSLWDAFFTLFAIAGVILIVRPTFLFGSNTSG--------MRES-YSEHIKGTFAAIGHAVLAAMTLVILRKMGKSVDYFLSIWYYVILGLPETIVVLFVIG--EWSLPYCGRDRLFLILIGLVGLGAQIFITKALQIEKAGLVAIMKTMDVVFAFIFQIAFFDNVPTWWTVGGALCVVVSTTGATIRRWLQSK-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2M3R5-1", "uniprot_id": "S35G1_HUMAN", "id": "Q2M3R5-1", "name": "Solute carrier family 35 member G1", "aln": "MRPQD-----STGVAELQEPGLPLTDDAPPGATEEPAAAEAAGAPDRGRCWLCLSSPCCSRTEPEAKKKAP-CPGLGLFYTLLSAFLFSVGSLFVKKVQD----------VHAVEISAFRCVFQMLVVIPCLIYRKT----GFIGPKGQRIFLILRGVLGSTAMMLIYYAYQTMSLADATVITFSSPVFTSIFAWICLKEKYSPWDALFTVFTITGVILIVRPPFLFGSDTSG--------MEES-YSGHLKGTFAAIGSAVFAASTLVILRKMGKSVDYFLSIWYYVVLGLVESVIILSVLG--EWSLPYCGLDRLFLIFIGLFGLGGQIFITKALQIEKAGPVAIMKTMDVVFAFIFQIIFFNNVPTWWTVGGALCVVASNVGAAIRKWYQSSK----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B4E3-1", "uniprot_id": "A0A8M3B4E3_DANRE", "id": "A0A8M3B4E3-1", "name": "Solute carrier family 35 member G1", "aln": "----------MRTLSEVPDGDAGESRPVNRGAFYRVCLPACCKRSDTHRDEDEDDGEEDTGENTVQKEKQPSCPGLGLMYSLLASVFFSIAALLVKKMEG----------MHAIQISAIRCFFQMLFVLPAMIYYKT----GFLGPRGMRIYLFLRGFLGSNAMILLYYAVLQMPLADATVIMFSNPVFTALLAWIFLKERCTIWDVVFTVFTLTGVILIARPPFLFGGELSG--------IEGD-YSSHIKGTVAAFSGAVGAACTMVILRKIGKRVHYFLSVWYYAVLGLIECVVVLFILD--EWTIPSCGWDRWTLMAIGVLGIAGQAFLTKALQIEKAGPVALMRTMDVVLAFVLQFLFLNRKPTWWSLGGALCVISSTSGVALRKWYNSTRQKS-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGN6-1", "uniprot_id": "Q9VGN6_DROME", "id": "Q9VGN6-1", "name": "EamA domain-containing protein", "aln": "----------MPENLELQQFQEGAPPPDPAP----------------------------RWLERLQRRLGADCPYLGILLATLSSLFFSLCSVIVKGLVD----------VNPMELASFRFVGVLLPALPILIYTRQ----PVF-PEGKRVILLLRCFMGTTGLMLSFYAFRHMPLADASVIIFSTPVFVAIFARAFLKEPCTLFNVLTINMTLLGVVLITRPPFVFGDTAES--------EDVAGKTYDIWGPVAAISSTLFGANVYILLRAL-KNLHFSVIMTNFGTIALVYTLIVCASIG--AVCWPSCGRDRWLVVVLGVFSFLGQILLTLSLQIEQAGPVAIARCADIVFAFVWQMLFFGETPTAYSLVGAVMVMGSVVLTALKKWAGTLPRESSLR------------KRFRLILLE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04835-1", "uniprot_id": "YM87_YEAST", "id": "Q04835-1", "name": "Uncharacterized membrane protein YMR253C", "aln": "-------MNPSVPKVMKRENNTHLLVSKEMNDTSLQLPSTTRSLSPKESNSNEDFNVDGNETTLQRISKDYLKPNIGLVLLTVSYFFNSAMVVSTKVLENDPDDIANDRQIKPLQILLVRMVITYIGTLIYMYINKSTISDVPFGKPEVRKWLVLRGCTGFFGVFGMYYSLMYLTISDAVLITFLAPSLTIFLSWVILRERFTKVEALGSLISLLGVVLIVRPSFLFGTPELTDSSSQ--IVESSDPKSRLIATLVGLWGVLGMSCVYIIIRYIGKRAHAIMSVSYFSLITAIVSFIGINTIPSMKFQIPHSKKQWILFGNLGVSGFIFQLLLTMGIQRERAGRGSLMTYTQLLYAVFWDVALYKHWPNIWSWIGMIIIISATLWVIRIRAANNETTAKDLTPIIDDEENSIPLTEFDLSDSK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08980-1", "uniprot_id": "YP264_YEAST", "id": "Q08980-1", "name": "Probable transport protein YPL264C", "aln": "-------------------------------------------------------------MTLQRISKDYLKPNYGLILLIVSYFFNSSMVVSTKVLENDPLETSQSR-INPLQILLVRMSITYCCTLVYMHWNKQSVPDIPWGPAPCRKWLILRGIMGFFGVFGMYFSLMYLSISDAVLITFMSPTLTIFLSFLLLGEPFSKLEALGSLISFSGVVLIIRPTFLFGEQTQGQQSPQDDIVETQNPKLRLIAIGVSLLGVCGLSSVYIIIRYIGNKAHAIMSVSYFSLVTTVVAALGVLLIPSMSLQLPHSWKQWGLFLNLGISGFIHQILLTMGIQRERAGRGSLMTYTQVIYAVFWDVVLFHHWPNIWTWCGMAVIVSSTIWVINMRASKQNVVAT---------AELLSTSDFELDDLED", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:. :: .: * : .* : . ::.::: .* : : : * *.** * .:: ::: .::** :* * * :. ::: * * : :.. ::: **:** **.*:** . : . ..: . : . :::* : : . : : : : : : * . : . :*: .: * ::* .:* *:** :: ::: *.. :. : . *. :: * :: : . : ", "identical_positions": 38, "similar_positions": 98, "identity": "8.96%" }, { "cls_id": "homologset.agr.MGI:2444790", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2Q0-1", "uniprot_id": "FND10_RAT", "id": "D4A2Q0-1", "name": "Fibronectin type III domain-containing protein 10", "aln": "MRAPPLLLLLAACAP----PSGAAVDP----------TPPGWEPA--------------------PDAPWCPYKVLSEGPEAGGGRLCFRSPVRGFRCQTPGCVTLASAGGSLRAHVLRNRSVLLQWRLAPAEAR--RVRVFALNCSWRGTYTRFPCDRVLLGASCRDYLLPDVHDSVRYRLCLQPLPLPLRAELAAAP---PELAECVEFTAEPAAMQEIVVAMTAVGGSICVMLVVICLLVAYITENLMHPTFR--RPSLRRQP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A9Q0-1", "uniprot_id": "FND10_MOUSE", "id": "A2A9Q0-1", "name": "Fibronectin type III domain-containing protein 10", "aln": "MRAPPLLLLLAACAP----PSGAAVDP----------TPPGWEPA--------------------PDAPWCPYKVLSEGPETGGGRLCFRSPVRGFRCQTPGCETLASAGGSLRAHVLRNRSVLLQWRLAPAEAR--RVRVFALNCSWRGTYTRFPCDRVLLGASCRDYLLPDVHDSVRYRLCLQ--QLPLRAEVAVVP---PELAECVEFTAEPAAMQEIVVAMTAVGGSICVMLVVICLLVAYITENLMHPTFR--RPSLRRQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F2Z333-1", "uniprot_id": "FND10_HUMAN", "id": "F2Z333-1", "name": "Fibronectin type III domain-containing protein 10", "aln": "MRAPPLLLLLAACAP----PPCAAAAP----------TPPGWEPT--------------------PDAPWCPYKVLPEGPEAGGGRLCFRSPARGFRCQAPGCVLHAPAGRSLRASVLRNRSVLLQWRLAPAAAR--RVRAFALNCSWRGAYTRFPCERVLLGASCRDYLLPDVHDSVLYRLCLQ--PLPLRAGPAAAAPETPEPAECVEFTAEPAGMQDIVVAMTAVGGSICVMLVVICLLVAYITENLMRPALA--RPGLRRHP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IYG0-1", "uniprot_id": "A0A0R4IYG0_DANRE", "id": "A0A0R4IYG0-1", "name": "", "aln": "MTRRQDSVLLGSCAILLFLNTGGSALPNRTSDVHNEATDSNKEPLRFPLELQHNSSAEGRLRVLGDSGPLCAYRSLGPG---DPGRLCFRYARPDFRCASGSCQQVSSGDGQLTANILTNGSVFIQWALSDSVAPPGQPGGFRLSCWWNGSYTQFECGGVHFGSSCRDYLLNELHTNVPYRLCMR----PYATD---------RAQACVEFSLAPGGMQDIVIAMTTVGGAICVMLVIICLLVAYITENIMNPTAHTHRSHLHTHL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :**.:** . .:. * * .. ** ..* *.*: * * . ****** . .*** : .* :... .* * :* * **::** *: : * : * *.* *.*:**:* * * :*:******* ::* .* ****:: * : . ****: *..**:**:***:***:******:***********:*.*: *. *: : ", "identical_positions": 95, "similar_positions": 56, "identity": "35.71%" }, { "cls_id": "homologset.agr.MGI:2444796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q499M5-1", "uniprot_id": "ANR16_RAT", "id": "Q499M5-1", "name": "Ankyrin repeat domain-containing protein 16", "aln": "MAPPGDPRRLCRLVQEGQLRALREELEVAGGCWDPEMFRGSQGPAGDTLLHFASRHGRQDILAYLVEAWSMDIEAANRDYKRPLHEAASMGHRDCVRYLLGRGAVVDSLKKADWTPLMMACTRKNLEVIQDLVEHGANPLLKNKDGWNSFHIASREGDPVILRYLLTVCPDVWKTESKIRRTPLHTAAMHGCFEAVQELLERCHYEPDCRDNCGVTPFMDAIQCGHVSIAKLLLENHEACSSATDSLGAQALHRAAVTGQDEAIRFLVCGLGIDVDVRAKSSQLTALLYAAKEGQTSTVQTLLSLGADINSTDERNRSALHLACAGQHAACARFLRQSGLKDSADLTGALAQQLTRGVAILQDFDPGVKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AS55-1", "uniprot_id": "ANR16_MOUSE", "id": "A2AS55-1", "name": "Ankyrin repeat domain-containing protein 16", "aln": "MALPGDPRRLCRLVQEGRLRDLQEELAVA---------RGCRGPAGDTLLHCAARHGRQDILAYLVEAWSMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAVVDSLKKADWTPLMMACTRKNLDVIQDLVEHGANPLLKNKDGWNSFHIASREGHPVILRYLLTVCPDAWKTESNIRRTPLHTAAMHGCLEAVQVLLERCHYEPDCRDNCGVTPFMDAIQCGHVSIAKLLLEQHKACSSAADSMGAQALHRAAVTGQDEAIRFLVCGLGIDVDVRAKSSQLTALHYAAKEGQTNTVQTLLSLGADINSTDERNRSVLHLACAGQHVACTRLLLQSGLKDSEDLTGTLAQQLTRSVDILQDFDHDVKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P6B7-1", "uniprot_id": "ANR16_HUMAN", "id": "Q6P6B7-1", "name": "Ankyrin repeat domain-containing protein 16", "aln": "MAQPGDPRRLCRLVQEGRLRALKEELQAAG---------GCPGPAGDTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAAVDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAIQCGHIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDVDVRATSTHLTALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLLQSGLKDSEDITGTLAQQLPRRADVLQGSGHSAMT", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **************:** *:*** .* *. ********* *:***::*:****.***.*****:****************************.**.****************** ***:**************************.*:**:*******..*****:************* :***: **:**:**** *******.:********:.:*:***::* ** ** **:*********************. **:******.*::**** ******:*.*:************.**:***.********* **:::* ******* *:**:*****.* . :**. . .. :", "identical_positions": 281, "similar_positions": 57, "identity": "75.95%" }, { "cls_id": "homologset.agr.MGI:2444797", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPI0-1", "uniprot_id": "XYLT2_RAT", "id": "Q9EPI0-1", "name": "Xylosyltransferase 2", "aln": "--------MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSGLEEDEPGEKGRQRKPRPLDPGEGSKDTDSSAGRRGSAGRRHGRWRGRAESPGVPVAKVVRAVTSRQRASRR------------VPPAPPPEAPGRQNLSGAAAGEALIGAAGFPQHGDTGSVEGAPQPTDNSFTPKCEIVGKDALSALARASTKHCQQEIANVVCLHQAGNLMPKSVPRHCQLAGKVSPG--------------IQWEEVRAQQPVSGPLVRIAYMLVVHGRAVRQLKRLLKAVYHEEHFFYIHVDKRSNYLYREVVELAQHYDNVRVTPWRMVTIWGGASLLRMYLRSMKDLLETPGWTWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDNSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYT--EDPLVAQLRQFYTYTLLPAESFFHTVLENSPACESLVDNNLRVTNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFLRLQQVS-RPTFFARKFESTVNQEVLEILDFHLYGSYPPGTPALKAYWENIYDMADGPSGLSDVLLTAYTAFARISLRHAAT-VSPLATAVCRFEPRGLPSSVHLYFYDDHFQGYLVTQAVQPSAQGPAETLEMWLMPQRLLKPLGHSDQASRLQSLEVGTEWDPKERLFRNFGGLLGPLDEPVAMQRWARGPN-------LTATVVWIDPTYVVATSYDITVDADT--EVTQYKPPLSLPLRPGAWTVRLLQFWEPLGETRFLVLPLTFNHKLPLRK-DDASWLHAGP--PHNEYMEQSFQGLSGILNLPQPEAVEEAARRHTELTGPALEAWTDGELSSFWSVAGLCAIGPSSCPSLELCRLTSWSSLSPDPKSELGPVKADGRLR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPL0-1", "uniprot_id": "XYLT2_MOUSE", "id": "Q9EPL0-1", "name": "Xylosyltransferase 2", "aln": "--------MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSGLEEDEPGEKGRQRKPRPLDPGEGSKDTDSSAGRRGSAGRRHGRWRGRAESPGVPVAKVVRAVTSRQRASRR------------VPPAPPPEAPGRQNLSGAAAGEALIGAPGFPQHGDTGSVEGAPQPTDNTFTPKCEIVGKDALSALARASTKQCQQEIANVVCLHQAGNLMPKSVPRHCQLAGKMSPG--------------VQWEEIRAQQPVGGPPVRIAYMLVVHGRAIRQLKRLLKAVYHEQHFFYIHVDKRSNYLYREVVELAQHYENVRVTPWRMVTIWGGASLLRMYLRSMKDLLEIPGWTWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDNSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYT--DDPLVAQLRQFYTYTLLPAESFFHTVLENSPACASLVDNNLRVTNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFLRLQQVS-RPTFFARKFESTVNQEVLEILDFHLYGSYPPSTPALKAYWENIYDVADGPGGLSDVLLTAYTAFARLSLRHAATAVSPLATAVCRFEPRGLPSSVHLYFYDDHFQGYLVTQAVQPSAQGPAETLEMWLMPQRSLKLLGHSDQASRLQSLEVGTEWDPKERLFRNFGGLLGPLDEPVAMQRWARGPN-------LTATVVWIDPTYVVATSYDITVDADT--EVTQYKPPLSLPLRPGAWTVRLLQFWEPLGETRFLVLPLTFNRKLPLRK-DDASWLHAGP--PHNEYMEQSFQGLSGILNLPQAEALEEAARRHTELTGSALEAWTDGELSNFWSVAGLCAIGPSACPSLELCRLTSWSSLSPDPKSELGPVKADGRLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1B5-1", "uniprot_id": "XYLT2_HUMAN", "id": "Q9H1B5-1", "name": "Xylosyltransferase 2", "aln": "--------MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSGLEEDEAGEKGRQRKPRPLDPGEGSKDTDSSAGRRGSTGRRHGRWRGRAESPGVPVAKVVRAVTSRQRASRR------------VPPAPPPEAPGRQNLSGAAAGEALVGAAGFPPHGDTGSVEGAPQPTDNGFTPKCEIVGKDALSALARASTKQCQQEIANVVCLHQAGSLMPKAVPRHCQLTGKMSPG--------------IQWDESQAQQPMDGPPVRIAYMLVVHGRAIRQLKRLLKAVYHEQHFFYIHVDKRSDYLHREVVELAQGYDNVRVTPWRMVTIWGGASLLRMYLRSMRDLLEVPGWAWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDNSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYT--DDPLVAQLRQFYTYTLLPAESFFHTVLENSLACETLVDNNLRVTNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFLRLQQVS-RPTFFARKFESTVNQEVLEILDFHLYGSYPPGTPALKAYWENTYDAADGPSGLSDVMLTAYTAFARLSLHHAATAAPPMGTPLCRFEPRGLPSSVHLYFYDDHFQGYLVTQAVQPSAQGPAETLEMWLMPQGSLKLLGRSDQASRLQSLEVGTDWDPKERLFRNFGGLLGPLDEPVAVQRWARGPN-------LTATVVWIDPTYVVATSYDITVDTET--EVTQYKPPLSRPLRPGPWTVRLLQFWEPLGETRFLVLPLTFNRKLPLRK-DDASWLHAGP--PHNEYMEQSFQGLSSILNLPQPELAEEAAQRHTQLTGPALEAWTDRELSSFWSVAGLCAIGPSPCPSLEPCRLTSWSSLSPDPKSELGPVKADGRLR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQZ8-1", "uniprot_id": "A0A8M3AQZ8_DANRE", "id": "A0A8M3AQZ8-1", "name": "Xylosyltransferase 2", "aln": "MRMIHGGKMVASTRVQKLLRRYKLVIAAGLTILLVQGLVVWSLRSLEEGEAERKHRRSKLP--DHNGQEQNLDPAIFDSGAN---HGQWRLRQDQPAV-TAIIRRGSRRRNKPPLKDKSFGGPEDGVAVEKVAHYDPSSSRNFSETRAGETAK--IHLVAPGEPGSVEGAPQVPSSDFVPKCEISGKDALSALHRAGSRQCRQEIANIVCQHQAGQLMPQSLPQFCPQHVISSAV--------------QHVDFADADLSKVENPVRVVFVLVVHGRAVRQLKRLLKAIYHKDHFYYIHVDKRSNYMHREVLKMAELYPNVRATPWRMVTIWGGASLLKAYLRSMHDLLSMLDWKWDFFINLSATDFPTRTNDELVAFLSQNRDKNFLKSHGRENARFIKKQGLDRLFHECDNHMWRLGERTIPEGLEVSGGSDWFSLTRKFVEYVVNS--QDELVTGLKQFYTYALLPAESFFHTVLGNSHMCDTLVDNNLRVTNWNRKLGCKCQYKHIVDWCGCSPNDFKPSDLIRIQQLT-RPTFFARKFESTVNQEAIEILDNHLYGQYPPGTVALKAYWESLFEQADGVSSLNDVALTAYSSFFRLGLRRQET--SQSSSEACRFEPIGYPVSVHLYFYDDRFQGYLVRQEVQNMVTRSREMLEVWAVPQATLQLEHNLHEFERLKHLEVGTEWDPKERIFRNFGGVMGPLDEPVAVQKWARGPN-------LTATIVWIDPAHIVAASYDISIDVEA--EYTQYKPPLQRPLRPGLWTVRVLRLWERVAEARFLVMPLAFKGREPLRT-DHG-WVHAGP--PGNVYLEQSFQQLAHVLKLPPSEPALQEAQKKTSLVGKPLEAWVDSSVGAFWVTGDTCSERTSSCPTIGLCSKTSWSSLSPDPKSELAPVKANGRIR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVA1-1", "uniprot_id": "XYLT_DROME", "id": "Q7KVA1-1", "name": "Xylosyltransferase Oxt", "aln": "---------MEQSVSARWLKRYRAFFLILLLIVAIQLFLAYKSLDIVGGGSGSGFDAAEAPASPPPPHAQARVQPPARTKLTAQQLGFQPECDILAREAISALQRAKTKDCREHIAQ--------IACAIQAGRFYAPQLRSSCPAGNHTANVSLGCFKDEKDRRLLAGYYSSSKTSNSP-AKCVELCLQSGYPYAGVQYGRECFCGYDPPPKASKLPDSSCNTKCLGNAKEICGGFYAMNIYETGIAKFTAQLAATTPSEETKRVRIAFLLTLNGRALRQVHRLLKALYAPEHVYYIHVDERQDYLYRKLLELESKFPNIRLARKRFSTIWGGASLLTMLLQCMEDLLQSN-WHWDFVINLSESDFPVKTLDKLVDFLSANPGRNFVKGHGRETQKFIQKQGLDKTFVECDTHMWRIGDRKLPAGIQVDGGSDWVALSRPFVGYVTHPREDDELLQALLKLFRHTLLPAESFFHTVLRNTKHCTSYVDNNLHVTNWKRKQGCKCQYKHVVDWCGCSPNDFKPEDWPRLQATEQKSLFFARKFEPVINQAVLLQLEEWLYGPYTSEYANLHGYWQSLYHHEDVHGSGDDLARSIGDSVMRLSAR------------QAKLYPLEL-IELTHYLHRDQYKGFLVRYRARGSTGKP-LHLETRVRPTQQGKLARNARFSKRLRNFEVSTDFDQKEQIARNFGKLLGPQSDLLLSYTLQANADSGAASHSYNLTLLWIDPLGRLQDFNELHVEDSTSDVINHSKTLLKHPITPGIWTAKLIGRNSIYAQLKFLIAPLAYYKGYPLAKSSDAEALNAGLTVALPEDFEMPVEWQQHLQTDDEQFTMREESLAKGKMLGQELHSWIDGLVGQFFQLRESCVVEADSEVSLPLCSDAPWSSLAPDPKSDVDALLK-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: : ::**: : * *: :* ::.:. .: . . : : . * . : : *. : . . .. :. . : : : : : * . ... * .: *. *. : :: :.. :*..* .: * : : . **:.::*.::***:**::*****:* :*.:*****:*.:*::*::::: . : *:* : *: ********* *:.*.***. * ***.**** :*:*.:* ::** *** * .:**:*.***:. :**:*****: * ***.****:*:* :* *: *.*****. *:* ** **. . :* *: * ::: ::************ *: * : *****:****:** ********:*************.* *:* :. *******..:** .: *: *** *.. *:.**:. :. * .. .*: : :. *:. : .:: * .: *:: *:::*:** .: . . ** * : . .**: :**.*::* **:: **** ::** .: : ..: . *::**** : :: :: .: .: *. *. *: ** **.::: . .: :**: **:: ** . ... ::** . :* ..: : . : : : .: * *.:* * :. *: * ... :: * :.****:*****:: .: ", "identical_positions": 240, "similar_positions": 254, "identity": "26.26%" }, { "cls_id": "homologset.agr.MGI:2444798", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MJU1-1", "uniprot_id": "A0A096MJU1_RAT", "id": "A0A096MJU1-1", "name": "", "aln": "----MVNTRKSSLRLLGSKSPGPGPGP--GAGVEPGATGGSS-HFISSRTRSSKTRAASCPAAKAGGSGGA---LDEARKAEVDGSLSDSHVSPPAKRTLKQPDSVCKDKSKS-RSTGQREEWNIPSGQARLTSQPGATLPNGHSSLSLRSHPLRGEKKG-DGDLSCINGDMEVRKSCRSRKNRFESVNQSLLFDQLVNSTAEAVLQEMDNINIRRNRRSGEVERLRMWTDTEFENMDMYSRVKRRRKSLRRNSYGIQNHHEVST----------------EGEEEESQEEDGDIEVEEAE-----GEENDRPYNLRQRKTVDRYQAPPIVPAHQKKRENTLFDIHRSPARRSHIRRKKHAIHSSDTTSS-DEERFERRKSKSMARARNRCLPMNFRAEDLASGILRERVKVGASLADVDPMNIDKSVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQRARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIALRRRYPQIYASSHKLQLDVSSIVLSAQDFYRAMQNIVPASQRAVMSSGQALSPIIRPLLERSFNNILAVLQKIFPHAEISQ---SDKKEDVENLILDDSEDENALSIFEMSCHSASPKK-SSPAAVTKPYLHFTMSPYHQPTSYRPRLLLSGERGSGQTSHLAPALLHTLERFSVHRLDLPALYSVSAKTPEESCAQIFREARRTVPSIVYMPHIGDWWDAVSETVRATFLTLLQDIPSFSPIFLLSTSETMYSELPEEVKCIFRIQYEEVLYVQRPIEEDRRKFFQELILHQASMAPPRRKHTALRAMEVLPLALPCPPRQLSESEKSRMEDQEENTLRELRLFLRDVTKRLATDKRFNIFSKPVDIEEVSDYLEVIKEPMDLSTVITKIDKHNYLTAKDFLQDIDLICSNALEYNPDKDPGDKIIRHRACTLKDTAHAIIAAELDPEFNKLCEEIKEARIKRGLSVTAEQVTPHGAGARKSETRVEEAFRHKQRNPMDAWHNSANKCAFRVRRKSRRRSQWGKGIIKKRKVNNLKKDEEDTKFTDYD-HTEDRKLLENGEFEVSTDCHEENGEETGDLSMTNDESSCDIMDLDQSQRLNSGAGTKENFASTEEESSNESLLVHSSSSLNPEQTSKKEPFLKGTCLNGEASTDSFEGIPILECQNGRVLEAAPLPGAGEKSSSEQKTALEEQLKDKPETANERHGDDPEKLEVLGYSSNE-IDPGPDGDGKDAELDKEGACKVKKYRK-LILEQAKTTNLELVPEEPSE---PVPPLVVDHERLQKLLDLLVDKSNNLTVDQLERLYSLLSQCVYRHRKDYDKSQLVEEMERTVHMFETFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULI0-1", "uniprot_id": "ATD2B_HUMAN", "id": "Q9ULI0-1", "name": "ATPase family AAA domain-containing protein 2B", "aln": "----MVNTRKSSLRLLGSKSPGPGPGP--GAGAEPGATGGSS-HFISSRTRSSKTRAASCPAAKAGGSGGAGVTLDEARKVEVDGSLSDSHVSPPAKRTLKQPDSVCKDKSKS-RSTGQREEWNLSTGQARLTSQPGATLPNGHSGLSLRSHPLRGEKKG-DGDLSCINGDMEVRKSCRSRKNRFESVNQSLLFDQLVNSTAEAVLQEMDNINIRRNRRSGEVERLRMWTDTEFENMDMYSRVKRRRKSLRRNSYGIQNHHEVST----------------EGEEEESQEEDGDIEVEEAE-----GEENDRPYNLRQRKTVDRYQAPPIVPAHQKKRENTLFDIHRSPARRSHIRRKKHAIHSSDTTSS-DEERFERRKSKSMARARNRCLPMNFRAEDLASGILRERVKVGASLADVDPMNIDKSVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIALRRRYPQIYASSHKLQLDVSSIVLSAQDFYHAMQNIVPASQRAVMSSGHALSPIIRPLLERSFNNILAVLQKVFPHAEISQ---SDKKEDIETLILEDSEDENALSIFETNCHSGSPKKQSSSAAIHKPYLHFTMSPYHQPTSYRPRLLLSGERGSGQTSHLAPALLHTLERFSVHRLDLPALYSVSAKTPEESCAQIFREARRTVPSIVYMPHIGDWWEAVSETVRATFLTLLQDIPSFSPIFLLSTSETMYSELPEEVKCIFRIQYEEVLYIQRPIEEDRRKFFQELILNQASMAPPRRKHAALCAMEVLPLALPSPPRQLSESEKSRMEDQEENTLRELRLFLRDVTKRLATDKRFNIFSKPVDIEEVSDYLEVIKEPMDLSTVITKIDKHNYLTAKDFLKDIDLICSNALEYNPDKDPGDKIIRHRACTLKDTAHAIIAAELDPEFNKLCEEIKEARIKRGLSVTSEQINPHSTGARKTETRVEEAFRHKQRNPMDVWHNSANKCAFRVRRKSRRRSQWGKGIIKKRKVNNLKKDEEDTKFADYENHTEDRKLLENGEFEVSTDCHEENGEETGDLSMTNDESSCDIMDLDQGQRLNNGAGTKENFASTEEESSNESLLVNSSSSLNPEQTSRKETFLKGNCLNGEASTDSFEGIPVLECQNG-KLEVVSFCDSGDKCSSEQKILLEDQSKEKPETSTENHGDDLEKLEALECSNNEKLEPGSDVEVKDAELDKEGASKVKKYRK-LILEQAKTTSLELVPEEPSE---PVPPLIVDRERLKKLLDLLVDKSNNLAVDQLERLYSLLSQCIYRHRKDYDKSQLVEEMERTVHMFETFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q166-1", "uniprot_id": "E9Q166_MOUSE", "id": "E9Q166-1", "name": "", "aln": "----MVNTRKSSLRLLGSKSPGPGPGPGAGAGAEPGATGGSS-HFISSRTRSSKTRAASCPAAKAGGSGGA---LDEARKAEVDGSLSDSHVSPPAKRTLKQPDSVCKDKSKS-RSTGQREEWNIPSGQTRLTSQPGATLPNGHSSLSLRSHPLRGEKKG-DGDLSCINGDIEVRKSCRSRKNRFESVNQSLLFDQLVNSTAEAVLQEMDNINIRRNRRSGEVERLRMWTDTEFENMDMYSRVKRRRKSLRRNSYGIQNHHEVST----------------EGEEEESQEEDGDIEVEEAE-----GEENDRPYNLRQRKTVDRYQAPPIVPAHQKKRENTLFDIHRSPARRSHIRRKKHAIHSSDTTSS-DEERFERRKSKSMARARNRCLPMNFRAEDLASGILRERVKVGASLADVDPMNIDKSVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQRARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALTALRRRYPQIYASSHKLQLDVTSIVLSAHDFYHAMQNIVPASQRAVMSSGQALSPIIRPLLERSFNNILAVLQKIFPHAETSQNFVAGSDLNCPSLEISSDYEETSIPEVKSSGKCFLGKKLCSKDSQGSTFVHLNFNMAFGPTSYRPRLLLSGERGSGQTSHLAPALLHTLERFSVHRLDLPALYSVSAKTPEESCAQIFREARRTVPSIVYMPHIGDWWDAVSDTVRATFLTLLQDIPSFSPIFLLSTSETMYSELPEEVKCIFRIQYEEVLYIQRPIEEDRRKFFQELILHQASMAPPRRKHTALRAMEVLPLALPSPPRQLSESEKNRMEDQEENTLRELRLFLRDVTKRLATDKRFNIFSKPVDIEEVSDYLEVIKEPMDLSTVITKIDKHNYLTAKDFLQDIDLICSNALEYNPDKDPGDKIIRHRACTLKDTAHAIIAAELDPEFNKLCEEIKEARIKRGLSVTAEQITPHGAGARKTETRVEEAFRHKQRNPMDAWHNSANKCAFRVRRKSRRRSQWGKGIIKKRKVNNLKKDEEDTKFTDYD-HTEDRKLLENGEFEVSTDCHEENGEETGDLSMTNDESSCDIMDMDQGQRLNSGAGTKENFASTEEESSNESLLVHSSSSLNPEQTSKKEPFLKGTCLNGEASTDSSEGIPVLECQNGRVLEVVPLPDGGEKSSSEQKIALEEQLKDKPETWNENRGDAAEKLEVLECSSSEKPEPGPDAEGKETELDREGASKVKKYRK-LLLEQAKPTNLELVPEEPSE---PAPPLVVDHERLQKLLDLLVDKSNNLTVDQLERLYSLLSQSIYRHRKDYDKSQLVEEMERTVHMFETFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13A7R6-1", "uniprot_id": "A0AB13A7R6_DANRE", "id": "A0AB13A7R6-1", "name": "ATPase family AAA domain-containing protein 2", "aln": "----MVNTRKSSE----HKPSSP---------FISGRTRSSQRNNPNLDEHNSRVRKRETPAAYS---------LRQPKEPSSDANSSSPRLSPPPKRTRRQTPPSSTDTSPSPQSKGQRGSWTMSKHCTRLSTG---ALQNGHT---IGRMSLRGDSTS-GGDHARMNGHVELKRSRRVRKSQFEHLNQSLLFDQLVNSTAEAVLQEMDNISSIRQSR--EVERLRMWTDTELENMDMYSRVKRR-KSLRRNTYGMQSHHKVMSKSKDPEEEEGTEESNEEGEEDEDVEADDDDEDDEGDEAEEAGEENDRPYNLRQRKTVQRYEAPPIEPVNRKQSKGSLFDTHRSPARRSHIRIKKHAIHSSESTSSSDEERFERRKSKSMSRARNRCLPMNLRAEDLASGVLRDRVKVGASLADVDPMNLDTSVKFDSVGGLTHHIQSLKEMVVFPLLYPQVFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDRKVSFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDSRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDKKARKHILEIHTRDWSPKLAEPFIDELAERCVGYCGADIKALCTEAALAALRRRYPQIYGSSQRYQLDVASIVLGPQDFGRALRSIVPAGQRALAPPGQALSCVLKPLLEPTLNQTLACLTRVFPHAELLHREHTHDSDNHLLVEDSYSEDEECLGASSIYETQSGSPKKAASCTTHKPFLHFTTSAYQQPTSYRPRLLLTGPQGAGQSTHLAPALLHHLEKFTVHRLDLPTLYSVSAKTPEESCAQVFREARRCVPSIIYMPHISAWWEAISETVKSSFLMLLQDVPSFTPLLILATAESVYQQLPDELKCIFSRSYGEVFCLSMPGEEARRKFFSDLILVQAAKAPPRR-RKSACALEVLTLSEDPGPRQLSAEEQRRLEEQEENTLRELRLFLRDVTKRLATDKRFQIFSKPVDIEEVSDYLEVITQPMDLSAIMMKIDKHKYMVAKDFLADIDLICSNALEYNPDKDPGDKIIRHRACSLKDTAHAMIASELDPEFDRMCEEIKESRRKRAPQTAPQPPVTPSTVATRKPMGEEAGLSSSQGD------GVDKHCSNNIKRKFRRRPIWGRGIIRKKKSYKKEEAEEDDEPEEEE-GAEDSTVMAQG-----------------DACLTLDESSCDTMELHPEKQPLQANG---HVLSTEEENSCEPTAARDAQ--GQEEAPSEEPTVAPTVP------------APQECVNGNESMDSVYSEAPDKDTIKR-----DALEQKPTEHKEASG--------TECSTGENTRTAEAVAS-DGDHEKEGSSKGKECGKGLSEVQAEEPAVRLQEAVQLP---PPPDLVVDHQRLKALLEQAVVKSEGFSVDHLERVFSALSQCIYQHRRDYDKTRLIEAMERQVEHFETFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P40340-1", "uniprot_id": "ATAD2_YEAST", "id": "P40340-1", "name": "ATPase histone chaperone YTA7", "aln": "MARNLRNRRGSDVEDASNAKVGYETQIKDENGIIHTTTRSLRKINYAEIEKVFDFLEDDQVMDKDETPVDVTSDEHHNNNQKGDDEDDDVDLVSPHENARTNEELTNERNLRK-RKAHDPEEDDESFHEEDVDDDEEEEEADEFEDEYLDEDSKDNNRRRRAADRKFVVPDPDDDEEYDEDDEEGDRISHSASSKRLKRANSRRTRSSRHPETPPPVRR-ALRSRTRHSRTSNEENDDENDNSRNEALTLADEIRELQEDSPIREK-----------RFLRERTKPVNYKLPPPLTASNAEEF---IDKNNNALSFHNPSPARRGRGG-WNASQNSGPTRRLFPTGGPFGGNDVTTIFGKNTNFYNQVPSAFSDNNNNKLILDSDSSDDEILPLGVTPKTKKENTQKKKKKK-PEIADLDPLGVDMNVNFDDIGGLDNYIDQLKEMVALPLLYPELYQNFNITPPRGVLFHGPPGTGKTLMARALAASCSSDERKITFFMRKGADILSKWVGEAERQLRLLFEEAKKHQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMDGMDNRGQVIVIGATNRPDAVDPALRRPGRFDREFYFPLPDVKARFKILQIQTRKWSSPLSTNFIDKLAFLTKGYGGADLRSLCTEAALISIQRSFPQIYRSNDKLLVDPSKIKVKVSDFMLALKKIVPSSARSTGSSPQPLPELIKPLLADQLNNLKNKLDYMLNIKDTTFQRNTSLLQNFIDYEEYSGEEE-------------EHDKYGGNEDTSSFRSYEFFESMAESQICKPRLLINGPKGNGQQ-YVGAAILNYLEEFNVQNLDLASLVSESSRTIEAAVVQSFMEAKKRQPSVVFIPNLDIWINTIPENVILVLSGLFRSLQSNEKILLLCLAENLDISEVKNGILSDFAFDKNIFQLHKPSKENITRYFSNLIELLKTKP-------SDIPMKKRRVKPLPELQKVTSNAAPTNFDENGEPLSEKVVLRRKLKSFQHQDMRLKNVLK-----------------IKLSGLMDLFKNRYKRFRKPPIDDAFLVHLFEPETSNDPNWQPAYIKD--------ENMILEVSTGRKFFNMDLDIVEERLWNGYYSEPKQFLKDIELIYRDANTIGDRER------------VIKASEMFANAQMGIEEISTPDFIQECKATRQRDLERQELFLEDEEKRAAMELEAKE---------------------QSQENILQEPDLKDNKANEFGVAAGNQLQAQLQTTINTASIVNNSEVPQPIDTNLYKKEIP----------------AAIPSAVDKEKAVIPEDSGANEEYTTELIQATCTSEITTDDDERARKEPKENEDSLQTQVTEENFSKIDANTNNINHVKEIQSVNKPNSLHETVEKRERSPIPKEVVEPEQGKKSDKELILTPEQIKKVSACLIEHCQNFTVSQLEDVHSSVAKIIWKSKSAWDKTGTVDEIIKFLSE-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * *. . * . : . . .: . * . .. : .* :.: : . . :. : . . : : . : . .: .* : . : .. ... : :.:* .:* .:.:. . .. . . * .* * :: ** * .. :.. :* : :*.. : * : . : .:.: ::*:.. .::: ... * .. . :.. ** . . .. : : : ..* .:. :.: . : :. **:.. .: .. :.: * ..:**:**:.:* .*.**.:*** ::*. *****.:*****:::::*:* **** **:*********:***** .**..::*::******** *******:********::* :******************:*:***:************:*.**:::******* *::************** * *** :** :**:*:**.*.. *: *:.:** ** ***:::******* :::* :**** *..: :* :.* : ** *::.***:. *: .. :.*. :::*** :*: * :: : : : . :* * . . : . . :****:.* :* ** ::..*:*: **.*.*:.***.:* * *::* * : .* * **:: **::::*::. * :::.:.* : *::.: * :::*. :*.: . .: ::: : * :* ::*.:** : . : .:: : :::: . ::: :.* * :: *.:.. * *:: . * :.** :: :.:: * : * *: * . * : *:. : :: . . :* .: :* * * .. .: : : . . : . .:*:: * . .. *.: : : : : :*. : ::. : . . :. : : . . ...:. :: : : . . . . :: . : .. . . * . : : :* . * : : . : . *:: :::: : : :.:.::*.:** :.* ::: ::: : :**: :: : : : ", "identical_positions": 279, "similar_positions": 433, "identity": "18.64%" }, { "cls_id": "homologset.agr.MGI:2444800", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5R212-1", "uniprot_id": "PRS35_RAT", "id": "Q5R212-1", "name": "Inactive serine protease 35", "aln": "---MLLWLIIFVSGWTLSLGSETEPDFTWHLSRIPQVVSEKTIHLASPTFQADAAAVKATVCGIECQEELPAPSLSQLEDFLSYETVFENGTRTLTRVKVQGLVLEPTQNSSIKGARPRRRRQVYGTDSRFSILDKRFLTNFPFNTAVKLSTGCSGALVSPNHVLTAAHCVHDGKDYVKGSKKLRVGVLKMRNKGGRKKRRGSRRSRREAESGGQ---SPEHPQESTTQ-RPGKKSRRGPRVAQGRPSFQWTRVKSTHIPKGWARGENGDPALDFDYALLELKRAQKQQYMELGVSPTISKLPGGRIHFSGFDNDRDDQLVYRFCSVSEESNDLLYQYCDAEAGSTGSGIYLRLKEPGQKNWKRKIIAVYSGHQWVDVHGVQKDYNVAVRITPLKYAQICLWIHGNAANCAYG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C0F9-1", "uniprot_id": "PRS35_MOUSE", "id": "Q8C0F9-1", "name": "Inactive serine protease 35", "aln": "MENTLLWLVILIPGWALSDGSETELDFTWHLSRIPQVVSENTIHLASPTFQADAGVVKATVCGIECQEELPAPSLSQLEESLSYETIFENGTRTLTRVKVQGLVLEPTRNSSVKGAHPRRRRQVYGTDSRFSILDKRFATNFPFNTAVKLSTGCSGTLVSPNHVLTAAHCVHDGKDYVKGSKKLRVGVLKMRNKGGRKKRRGSKRSRREAESAGQ---SQAHLRESTTQ-RPGKKSRRGPRVTQGRPSFQWTRVKSTHIPKGWVRGENGGLALDYDYALLELKRAHKQQHMELGVSPTITKLPGGRIHFSGFDNDRDEQLVYRFCSVSEESNDLLYQYCDAEAGSTGSGIYLRLKEPGQKNWKRKIVAVYSGHQWVDVHGVQKDYNVAVRITPLKYAQICLWIHGNAANCAYG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3Z0-1", "uniprot_id": "PRS35_HUMAN", "id": "Q8N3Z0-1", "name": "Inactive serine protease 35", "aln": "MENMLLWLIFFTPGWTLIDGSEMEWDFMWHLRKVPRIVSERTFHLTSPAFEADAKMMVNTVCGIECQKELPTPSLSELEDYLSYETVFENGTRTLTRVKVQDLVLEPTQNITTKGVSVRRKRQVYGTDSRFSILDKRFLTNFPFSTAVKLSTGCSGILISPQHVLTAAHCVHDGKDYVKGSKKLRVGLLKMRNKSGGKKRRGSKRSRREASGGDQREGTREHLRERAKGGRRRKKSGRGQRIAEGRPSFQWTRVKNTHIPKGWARGGMGDATLDYDYALLELKRAHKKKYMELGISPTIKKMPGGMIHFSGFDNDRADQLVYRFCSVSDESNDLLYQYCDAESGSTGSGVYLRLKDPDKKNWKRKIIAVYSGHQWVDVHGVQKDYNVAVRITPLKYAQICLWIHGNDANCAYG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****::: .**:* *** * ** *** ::*::***.*:**:**:*:*** : ********:***:****:**: *****:**************.******:* : **. **:***************** *****.*********** *:**:*************************:******.* ******:******....* : * :* :. * *** ** *:::***********.*******.** *. :**:**********:*:::****:****.*:*** ********** :**********:*************:******:*****:*.:*******:*************************************** ******", "identical_positions": 309, "similar_positions": 62, "identity": "74.82%" }, { "cls_id": "homologset.agr.MGI:2444804", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RC54-1", "uniprot_id": "M0RC54_RAT", "id": "M0RC54-1", "name": "", "aln": "MATNPQPQPPPPAPPPPPPQPQP--PPPPPGPGAGPGASGPGGAGAGSGDPQLVAMIVNHLKSQGLFDQFRR-DCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVLKSGMLESGIDRIISQVVDPKINHTFRPQVEKAVHEFLATLNHKEETAGSTAPDDEKLESSVITQGAPAPGPSANVASDAMSILETITSLNQEANAAARASTEMSNAKASERISRKLSSQPSTDISTDKERGSEDGAEREKVTPDSGGEGLETAPKSEEPNDLPCPVEETKNHTKEN-SLLFLSKDAQQENSDPKIKSTDKGEKKPDGNEKGERKKEKKEKTEKKIDHSKRNEDTQKVKDERQAKDREAESTKLPSEKISSRARAAEGTKEDCSLVDSD-VDGLTDITVSSVHTSDLSSFEEDTEEEVVMSESMEEGEITSEDEEKNKQNKTKAQTSDSTDGKARSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRRINREKLEEKRKQKAEKTKSSKAKSQGKSSVDLEDSSTKTLEPKAPRIKEVLKERKVLEKKVALSKRRRKDSRNADESSKKKPQAEEESKEALKTSEHCEKEKASS-KDLKHTHGKGEPNRPARRLSESLHSVDDNKTESKVEREYKRRTSTPVVLEGAQEETDSRDGKKQPDRSEINMEETQKQKSTLKNEKYQKKDDPET-HGKGLPKKEAKSAKERPEKEKAQSEEKSSSKHKHKSDSVHKVGDETEPHSSEKS-EAEESVRKQSQQTKLSSDDKTERKRKHRNERKLSVLGRDGKPVSEYTIKTDEHARKDN-KKDKHLSSEKTKAEHKSRRSSDSKLQKDVLSSKQHSVTLQKRSESCSEDKYETDSTNADSSSKPEELLHKERRRTKSLLEEKLVLKSKSKSQGKQIKVAETESQEGVTKQVTTPKPDKEKNTEDNDTERQRKSKLEDRTCEEAVAEPALESAVPSAHSSQKDSGHRAKVASVKEKHKTDKDSTSSKLERRVSDGHRSRSLKHSNKDVKRKEENKPDDKNGKEVDSSHEKGRGNGPVTEKKLSRRLCENRRGSTSQEMAK-EDKLAANLSGTASTSSLQRPKKSTETALIPEQEPMEIDSEAAVENVSELSKTEDISSNSSQQDTDFENVTKHKAAAGVLKDELRTSMVDSKPAAAVTCKSGRGLTITSNSEKHADHKSTLTKKVHSQSTASKATPREREPAQRGAQEISVDSEGSRKVLSRALSENEKGQKNLKGVSKTTEECGTHRNASLEFSTDSDLLSSLGSVSVVPQKESHDSSTITVVDREAISEGGKASTSLVNHSDIPNQNLAVKKSEILKTNGSKEGNDGFTVDILAKANGSGKRHLSEDSQAMLLCSKEGKVGIALAGKPSGVIGENKSISKQRSLMGTAKKESDLNVDPDVKQ-----------DSAAGEHVVDLTTRKEAETIRRKHNKDPDESKKIPTDIERKTENSEVDTSARRDSAP-VPQQRHGKMERGAAGSGRRDKSFIATSTEGTDKGIMLNTIKAGDATTTSSETGGKGVALPCTSIEADEGFIMGACPRNNPLQVGAEASECTVFAAAEEGKGVVTEGFAESEILLTSSKEGESGECTVAESEDRVAGPLTAHTVQAETNVNSITTEEKDDAVTSAGSEEKCGGSSCA----VEGTATFVGEVESDGAVTSAGTEIRAGSVSSEDVDGSQENRIQVGPKKETEGTVTCTGAKGRNDNFVFCLVTGAGTQEQRVVTGADVVQENDDKSLEASANQ-GDGSGTDGTEGESAVTSTGITEEDGEASANCTGSEDSTEGCAISSETEENAESAMDSTEAKDMTNTPLVATGPCDDEGIVTSTGAKEEDEEDEGVVTSTGRGNETGHASACTGIEE-SEGMLVCESGEGGGPIGPTMDHVDAEAGAAAMNTNDSNVDSMSGAEKEIKDTDICSSAKGIVESSVTSAFAGNSDRPPVLESSENPMASATSHHSDSQLTRKETVEDTTISTGLVRGSDDVLLSGAVPEYEVGHMSPRE-----------NEECDGLMASTASCDVSNKDSLAGSKSQGNGLVIPTS-TNDCTPPISAVIDVRGGHSCTLSTEENRNDARVHMEGFEAPMPSAISDEKSQLTASRSEEKDECAMISTSIGEEFEVPISSAVTITCAERQQPVAA-VEESTTGPALVSTEDFEIPMPSAPTEAESPLASTSKEEKDECALISTSIAEECEASASGVSRNAP----------SDGNAVISTSSVEDCEGSVSSAVPQESVCPSVVPVEETGDTAMISTSTSEGREAVMVGTIPTDEDQASTVRGEDLSDAAIISTSTAECVLTCTSLSRHEESQQASTHNPRGNGGRLVTKQSKCELPMPSLMTESNCKCPGPFTTGKGVGPLMAVSTRGEHDRLPVCEPSAGQSQPGTALCLGEEKSHGMDCPGQD--------------LNAKERNTLLSCVQRESKSVEAEAAGDSSTASGIVRKDSERNANSLSETNCLRRPEQKSAEDSSGSIHCLAAVNTG-AKTDNMLPITDAASECPS---DQQEPENNLKA-TTKCITGQESKMPSSHTAVLPSVCRVAPSAPKREGGLPAKSDHSGTWTSEGSAEKMGHVAGARQSYHREGNLDVTIPPEDNGCGIGNEELPPKGIEGSELSANLTTEISVSSEEDTNHGVVAAPENPCVGRPSGAAELQVEALLMSESLNVENSESRINEEIHYDSRNKEEISCGRKDSTEALSGCSAEADPEEVEEEERHISKRNRKQDYSSEEEELDDSPDVLDSRIQTAQRQCSETEPHDTKEENSGDLEEFSTLNSKANSSPA--LEDRDEFSSSEGTGEKIEPNEDDGSVKSQEDDQPIIIKRKRGRPRKYPAETAFKSKEDSKTETDITTVEQSPPGDKLKVSQADEFNKETTDLQEKSTSNDDNEEKTGS-VRRRGRKPKRSLTSSDDAESSEPERKRQKPFSETSEDKNDQDSDEEEEEEDEDEPLGATTRSATRSEAQRKNHSKPSTRATSKLGIPETVSPRNRQKLAKEKLSTSEKVSKSPPLGRSKAQLSPSVKRKRELSPPGARTRGQQKVDETPLKKAKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q6J5-1", "uniprot_id": "BD1L1_MOUSE", "id": "E9Q6J5-1", "name": "Biorientation of chromosomes in cell division protein 1-like 1", "aln": "MATNPQPQPPPPAPPPPPPQPQP--PPPPPGPGAGPGASGPGSAGAGAGDPQLVAMIVNHLKSQGLFDQFRR-DCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVLKSGMLESGIDRIISQVVDPKINHTFRPQVEKAVHEFLATLNHKEEAAGSTAPDDEKPESSVITQGAPAPGPSANVASDAMSILETITSLNQEAN-AARASTEMSNAKVSERTSRKLSSQPSTDVSTDKERGSEDATEREKATSDSGGDGLEAALKSEEPSDLPCPVEETKNHMKENNSLLLLSKDAQQESTDPKIKSMDKGEKKPDGNEKGERKKEKKEKTEKKIDHSKRNEDTQKVKDERQAKDKEVESTKLPSEKSNSRARAAEGTKEDCSLLDSD-VDGLTDITVSSVHTSDLSSFEEDTEEEVVVSESMEEGEITSEDEEKNKQNKAKVQPGDSSDGKARGVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRRINREKLEEKRKQKAEKTKSSKVKSQGKSTVDLEDSSAKTLEPKAPRIKEVLKERKVLEKKVALSKRRRKDSRNVDENSKKKPQAEEESKEALKTTEYCEKEKASS-KDLRHTHGKGEPSRPARRLSESLHSADENKTESKVEREYKRRTSTPVILEGAQEETDTRDGKKQPERSETNVEETQKQKSTLKNEKYQKKDDPET-HGKGLPKKEAKSAKERPEKEKAQSEDKPSSKHKHKGDSVHKMSDETELHSSEKG-ETEESVRKQGQQTKLSSDDRTERKSKHKSERRLSVLGRDGKPVSEYTIKTDEHARKDN-KKEKHLSSEKSKAEHKSRRSSDSKLQKDALSSKQHSVTSQKRSESCSEDKCETDSTNADSSFKPEELPHKERRRTKSLLEDKVVSKSKSKGQSKQTKAAETEAQEGVTRQVTTPKPDKEKNTEDNDTERQRKFKLEDRTSEETVTDPALENTVSSAHSAQKDSGHRAKLASIKEKHKTDKDSTSSKLERKVSDGHRSRSLKHSNKDMKKKEENKPDDKNGKEVDSSHEKGRGNGPVTEKKLSRRLCENRRGSTSQEMAK-EDKLVANMSGTTSSSSLQRPKKSTETTSIPEQEPMEIDSEAAVENVSELSKTEDISSNSSQQDTDFENVTKHKATAGVLKDEFRTSMVDSKPAAAVTCKSGRGLAVTSISERHADHKSTLTKKVHSQGNPSKAAPREREPIQRGAQEVSVDSEVSRKALSRAPSENEKGQKNLKGMSKTTEECGTHRNASLEYSTDSDLLSSSGSVTVVPQKESHNSNTIPVIDREAISEGGRASTSLANHSDVPNQYSTVKKSEVHKTNGSKEGNDGFTVDMPTKANGGSKRHLSEDSQATLLYSKESKISIPLADKSMSVTGDNKNINKQRSLMGTAKRESDLKVNPDIKQ-----------DSAAGEHVVDLSTRKEAETVRRKHN------KEIPTDVERKTENSEVDTSARRDSAP-VPQQRHGKMERGAAGSGRRDKAFIATSTEGTDKGIMLNTVKTGDATTTSSEVGEKGTALPCTSIEADEGFMMGACPKKHPLQVGAEASECTVFAAAEEGKGVVTEGFAESEILLTSSKEGESGECAVAESEDRVAGPLAAHTVQAEANVNSITTEEKDDAVTSAGSEEKCGGSACT----VEGTATFIGEVESDGAVTSAGTEIRAGSLSSEDVDGSQENRIQVGPKKETEGTVTCTETKGRNDNFI-CLVTRVETQEQRVVTGADVVQVNAAKPQEANANQ-GDGSGTDGAEGESAVTSTGITEEDGEASANCTGSEDNREGCAISSETEESAESAMDSTEAKDITNAPLVAAGPCDDEGIVTSTGAKEEDDEDEGVVTSTGRGNEPGHASACTGIEE-SEGMMVCESGEGGAQIGPTIDHVNAEAGAATVNTNDSNVDSMSGAEKEIKDTNICSSAKGIVESSVTSALAGNSDRPPVLCGSEGPMASASSHHSDSQLTRKETVEDTTISTGLVKGSDDVLVSGEVPECEVGHMSPRK-----------NEECDGLMASTASCDVSNKDSLAGSKSQGNGLMISTS-TNACTPQISAVIDVRGGHLSTLSTEEIRDGVRVHREGFEAPMPSAVSGENSQLTASRSEEKDECAMISTSIGEEFELPISSAVTVTCAERQQPVAA-VEESTTGPALVSTEDFEVPMPSAPTEAESPLASTSKEEKDECALISTSIAEECEASVFGVSRNAPSV--------TDGNAVISTSSVEDCEGSVSSAVPQESVCPSVIPVEETGDTAMISTSTSEGREAVMVGTIPTDDDQATTVRGEDLSDAAIISTSTAECVLTCTSLSRHEENQQA-THNPEGNGGHLATKQSKCELPMPSLVAERNCKCPGPFRMGKGVGPLMAVGTRGEHDRLPVCEPSVGQGQPGTALCLGEEESHGMDCPGQD--------------LNAKERNTLLSSVQRESKSAEAEAAGDSSTARRTVRKDSERNANSLSETNCLREPEQKPAEDTSGSTHCLTAVNPG-AEADGMLPITHAALEYP----DHQEPESNLKT-TTKCITGQESQMPSSHTGVLSAVCHVAPCASEQEGGLPTKSDHSGTWTSEGSPEKMGHVAGARQSFHREGNLDVTLPPEDNGCGVGNEESPPKGIGGLELSTGLTTEISVSSEEDTSHGVVAAPENPCVGRRRGAAELQMEALLMRESLNVEKSESRINEEIHFESQNKEEICCGRKGSTEALSGCSVEADPEEVEEEEKQISQRNRKPDYSSSEEELDDSPDVLDSRIETAQRQYSETEPHDTKEENSGDVEEFSSVTSKTNSSTG--LEDRDEFSSSEGTGEKTEPNEDDGSIKSQEDDHPIIIKRRRGRPRKYPAETAFKSKEDSKTETDITTVEQSSPSGKLKVSQADESNKEIANLEEKSTSNDDSEEKTAS-MRLRGRKPKRSLTSSDDAESSEPERKRQKSVSETSEDKKDEESDEEEEEEEEEEPLGATTRSATRSEAQRKNHSKPSTRATSKLGIPETISPRNRQKLAKEKLSTSEKVSKSPPLGRSKAQLSPSVKRKREVSPPGARTRGQQKVDENPLKKAKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFC6-1", "uniprot_id": "BD1L1_HUMAN", "id": "Q8NFC6-1", "name": "Biorientation of chromosomes in cell division protein 1-like 1", "aln": "MATNPQPQPPPPAPPPPPPQPQPQPPPPPPGPGAGPGAGGAGGAGAGAGDPQLVAMIVNHLKSQGLFDQFRR-DCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVLKSGMLESGIDRIISQVVDPKINHTFRPQVEKAVHEFLATLNHKEEGSGNTAPDDEKPDTSLITQGVPTPGPSANVANDAMSILETITSLNQEAS-AARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSD-VDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDSEPGVENVFEVSKTQDNRNNNSQQDIDSEN-MKQKTSATVQKDELRTCTADSK-ATAPAYKPGRGTGVNSNSEKHADHRSTLTKKMHIQSAVSKMNPGEKEPIHRGTTEVNIDSETVHRMLLSAPSENDRVQKNLK--NTAAEEHVAQGDATLEHSTNLDSSPSLSSVTVVPLRESYDPDVIPLFDKRTVLEGSTASTSPADHSALPNQSLTVRESEVLKTSDSKEGGEGFTVDTPAKASITSKRHIPEAHQATLLDGKQGKVIMPLGSKLTGVIVENENITKEGGLVDMAKKENDLNAEPNLKQTIKATVENGKKDGIAVDHVVGLNTEKYAETVKLKHKRSPGKVKDISIDVERRNENSEVDTSAGSGSAPSVLHQRNGQTEDVATGPRRAEKTSVATSTEGKDKDVTLSPVKAGPATTTSSETRQSEVALPCTSIEADEGLIIGTHSRNNPLHVGAEASECTVFAAAEEGGAVVTEGFAESETFLTSTKEGESGECAVAESEDRAADLLAVHAVKIEANVNSVVTEEKDDAVTSAGSEEKCDGSLSRDSEIVEGTITFISEVESDGAVTSAGTEIRAGSISSEEVDGSQGNMMRMGPKKETEGTVTCTGAEGRSDNFVICSVTGAGPREERMVTGAGVVLGDNDAPPGTSASQEGDGSVNDGTEGESAVTSTGITE-DGEGPASCTGSEDSSEGFAISSESEENGESAMDSTVAKEGTNVPLVAAGPCDDEGIVTSTGAKEEDEEGEDVVTSTGRGNEIGHASTCTGLGEESEGVLICESAEGDSQIGTVVEHVEAEAGAAIMNANENNVDSMSGTEKGSKDTDICSSAKGIVESSVTSAVSGKDEVTPVPGGCEGPMTSAASDQSDSQL---EKVEDTTISTGLVGGSYDVLVSGEVPECEVAHTSPSEKEDEDIITSVENEECDGLMATTASGDITNQNSLAGGKNQGKVLIISTSTTNDYTPQVSAITDVEGGLSDALRTEENMEGTRVTTEEFEAPMPSAVSGDDSQLTASRSEEKDECAMISTSIGEEFELPISSATTIKCAESLQPVAAAVEERATGPVLISTADFEGPMPSAPPEAESPLASTSKEEKDECALISTSIAEECEASVSGVVVESENERAGTVMEEKDGSGIISTSSVEDCEGPVSSAVPQEEGDPSVTPAEEMGDTAMISTSTSEGCEAVMIGAVLQDEDRLTITRVEDLSDAAIISTSTAECMPISASIDRHEENQLT-ADNPEGNGDLSATEVSKHKVPMPSLIAENNCRCPGPVRGGKEPGPVLAVSTEEGHNGPSVHKPSAGQGHP-SAVCAEKEEKHGKECPEIGPFAGRGQKESTLHLINAEEKNVLLNSLQKEDKSPETGTAGGSSTASYSAGRGLEGNANSPAHLRGPEQTSGQTAKDPSVSIRYLAAVNTGAIKADDMPPVQGTVAEHSFLPAEQQGSEDNLKTSTTKCITGQESKIAPSHTMIPPATYSVALLAPKCEQDLTIKNDYSGKWTDQASAEKTGDDNSTRKSFPEEGDIMVTVSSEENVCDIGNEESPLNVLGGLKLKANLKMEAYVPSEEEKNGEILAPPESLCGGKPSGIAELQREPLLVNESLNVENSGFRTNEEIHSESYNKGEISSGRKDNAEAISGHSVEADPKEVEEEERHMPKRKRKQHYLSSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDD-TIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQR-----------------------------------------------SKTQLSPSIKRKREVSPPGARTRGQQRVEEAPVKKAKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B8C2-1", "uniprot_id": "A0A8M3B8C2_DANRE", "id": "A0A8M3B8C2-1", "name": "", "aln": "------------------------------------------MAALHPGDPQLVSVIVNHLKTEGLFDQFRR-DCLADVDTKPAYLHLRQRVDNFVSNHLANHTWSPQLNKNQLRNSIRQLVQQSGMLEQGVDRIVAQVVDPKVHHTFRPQVERIVRRFLSPHSHLEEEE---------------LPAVAPPLPAEHLEAEVLIQDDAAVSWSADVQMSESAGAESN------------------------------------------------LELSVEEMDISLPEEEEELQLKEEEPLLEEEEQPQVKEEEPHVKEAELETQEAVLKEEPKEEADASKETSSKSSGKSREENPETDSQK----------------PTSVKQKTRERLREEYSLEDSD-LEGLSDITVSSVHTSDLSSFEGDSEEDEAPSESTEEGEISSEEDGGRK------TPADGSDRKPRGVRQGYVHKPFLYSRYYSDSDDEVTVEQRRRSVAKEKEERLLKRQQNRERMEEKRRLRAAQREEQERKKQASVCADAR-----------PRAKEARKEKKFLEKKVALSRQRKRDSRKEDDRKRSDTEGDSLNKEVKPAGQRSGR------------------------------VDEQRRKKSDTEEKLCDRNRVHSFILDLESGTEER--------------------------------------------QRTKTARKEVHLKDKERKDEHKLKHKLKMDSRKSTDTDEKDGGAGKG------------------GAEEKKGSKVKPDRKSSVTSKDT--------KTPEAADEANLKKGKMAADAKDKEKPKTSGKSESKLLR------------RLDSTGSSEERSEVETG--------SEVNRKKDKHPKEMLKR--------------------------SKSHPEPHPEARPGEKLKVRADRRDSSVDKTQAQKSGSEPEGD----------------------------GRKPETSLKSKTLLEKHRSKSQNPAGGKPERKTEAKSKPAEDK---------REEKKTSEEKLRDTKVRKLKVQKDSKFEE----------------------ESLDSAAVSSSTPVSDDPFAALSDVTPESEDEEVEPKEPRPLSAEADALLSLMDISVRRDVEADMKMQEAALTLLSMGPDAGRSSDVVAADDQVAMQTVATDPEDAGSLPECAAADAAAPAATVEPMETESLRLQEVTSQSGDE---------------------------------------------QKEERDTHTHTTDTAQTLSADTAEPTLENTAADEPMQTPSADAAEPLEPVTAAEPASPVTEDAAEQRQTSS----ADETPAQTLPKHTAETHTPTTVNPAEPTAESAQMEES---------------------------------------------------------------------------------------------DEPEPVQILSAGTAESAQTHAAEEPAQTHAADEAESAQTLTADTESAQTRNADLNEPVLKMNADQAEHVQTHS--------ADDAECVQTPTAET---------------------------------------MRIYNADADVPAQTIHADEAESVQTPT------------------------AETDEPVETADADTSEPAQTLTADEADSAQTHIADTEP-------------------------------AQTLTADTVKTLNADEAEPVQTVDQDETVQMVDADEVESAQTLT----------------------------TETDGTAEMDNAEPAHTLTANEAEHELTADEAKSAQTLTADEADSAQTLTADEAKS-------------------------------AQTLTADEANSAQTLTADEAESVQTLTADEADSAQTLTVDEAK---------------------------------------------------------------------------------------------------------------------------------------SAQTLTADEADSAQTLTADEADSAQTLTADEAKSAQTLTADEAKSAQTLTADEAEHEQTLNADEA--------DSAQTLTADEADSAQTLTADEADSAQTLTADEADSAQMLTADEAESAQMLTADEAEHG------------------------------------------------------KTLNANEAESAQMLTADEIKTDRMLAADTDEPAQTLTAETAAP---------------------------------------------------------------------------------------------------------PSSSGEQESAAAAAEDEDGD------------------------DDEEDTRVSRTPRRGRSSRAAEAPQRETRSASQPKEVEP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVEEEPKEQSRRGR--------------------RSAAQTRDTPAVKPALKRKRSDEELKEDPEPSAKHRRDAVSPAGDQDASKASDEEEERKEEEEEETTEDQQRK------PARRGRPSK-------------------------------ASSATDDSDTGASEKRDGEKEEDEEEEKKSR--------ATTRAASRLEAERNKPSKPSTRALSKLSKEENTPHTRSVRG-------------------------------------------------------------------------------RKRDPSPPVSRTRGGQKSEDPAAKRAKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHZ9-1", "uniprot_id": "A0A0B4KHZ9_DROME", "id": "A0A0B4KHZ9-1", "name": "", "aln": "-------------------------------------------------MDDFIKTLIAEVKSQGVFDEFRFNCCLADVDTKPAYQNVRTQVETAVNDFLAKQQWTPETNKVQLRERLRKHLMDSDVLDKGVDQIVDQVVNPKVATIFEPKIESIVYKYLG---------------------------ITPPARPTMLSAPPLPPFGAHLNGSSLLN----------------------------------------------------------------------------------------------VETTVGLLPTDLEQISPDSDRATVKSESRDDELPPGVDDEDTSPSYELVSER--------------------KTLAIKEELNNVSLNNSDSVNGVSQASQLSQVSSDSRLTMASSTESMVDSHQHTAAHNSGEPENICEEAQMPKFSENSWDASAGTGRSEGRQLHFDIKQDAITFEG----TERKNSVSETTSTGLQILSIEDEIMSEVKANIDDANNASIESIAPEP------------------------VQVPAPPKVNPPPPPRPASPKVEPPPPAPPGVESPPGPQPPASPRFDP-------------------------------------PPPHTIEPPPPPAPPTLVP--------------------------------------------------------PPPPAPPTIKPPPPPAPPTVEPPPPPPPAPPTVEPPPPPPPAPT-----------------------KVEPPPPPAPAEVEPPPPPAPTELEPPPPPAPPKVELPPPPAPPKAEAAITPRRAKGSNG----------------------------------------------------------------------------------FITELAVTPKESETRDKPHNVNTDVKEDEQPATTEDKQDKPLELG---------------------------LDAPKDAVSTASESTESPTSTSSQSKSHSKSRDKEKEKD--------------RRHHRHSDDKHRRRSTDRDRDRSRD--------------------------KSHSKHSSSSSSKHSSSNSSSSKHKSSSSKNDKSSSSSSSRSNRESSSSKRSGTTSSSRHESSSHKKHKSSSSSSRSERDKGKEKDKEREKDSQSRSHHSSSSSSSSSRRKDHDRGRD---------------------------------------------------------------------------------------------RDRNKSNTSGSAENKAIHDDHSESKEKYKQRRGSDSNDEGKPPSSGGPAKNSQPEDSAATMKSDAPVENANGTNGNSNGSTN----------------------------------------------------------------------------------------------------------------GACDNVSGVVIVSDILQQSTSSFVELTAGSQSHDRAESSKHEPED--------------------------------------------------------------------------------IDGKEADNQPEKTELEARQ------------------------------DECASQNEVPTVEPQTLADSVPDLPAKESMDTLE-----------------------------------DEKVETNVEENKSEEESKPENPPEECVDEPAQVGDVED----------------------------------------PPQDADKPATPVPISNEQSDEFSADFVTHFEENTDEFRTRLQLIN-------------------------------------------------QLIEDRKNLLNRLSEDGTQEEAVDIR----------------------------------------------------------------------------------------------------------------------------------------------ALRRSLSKRRRSSMQEQHRVERETTPPQPRSPSSSSTAGSPAKRLRQDEPKSS---------------PTPSDASINSKENEALEKQEHADALSARRLSKKLCQQQRYTNDDLYKPRPILSQRSRRRGLDSIL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: :: .:*::*:**:** *********** ::* :*:. * :.**.: *:*. ** ***: :*: : .*.:*:.*:*:*: ***:**: *.*::* * .:*. ..* . : : : . . . . : .. .. .. . ..: . .. . . : .:. : : : :: ** :** ::*::: : * :** .: *. . *.. .. :.: : : . :. : .. * : : .: :. :*:.*::: .. * : * :.* : : . . : ** . : * : : :. : . : .: .. : . : . : .* . : : . : : *:. :. *: . . : :. . :: . : : * * : . . .:. * : . * . :.* . : . :* . ... . . .. .. *: :. ... . :. .. : . * . . :.. . : . . : :* : . . . . . .: * : : *. . . . : :: . : :. : : * . .. . .. * ::. .. : : : :.. .: . : . * . : :* : . . :: :: . :: . : :: .:. . : : . . * ::.. * : :. * . . : : . .:. ", "identical_positions": 86, "similar_positions": 301, "identity": "2.76%" }, { "cls_id": "homologset.agr.MGI:2444807", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AI01-1", "uniprot_id": "A0A8I6AI01_RAT", "id": "A0A8I6AI01-1", "name": "Zinc finger protein 827", "aln": "MPRRKQEQPKRLPSHVSRQDE--AEGDFSEGEQWYGNSSETPSEASYGEVQENYKLSLEDRIQ-EQSTSPDTSLGSATPSS-HTLELVALDGEVLRDSLQCQGHLSPGVSSVCDDDPPSSNKPLSSNLRRLLEAGSLKLDG---TANGRVESPVNVGPSLSFSPPSHHAQQLSVLARKLAE-------------------KQDQSDQYTPSNR-------FIWN--QGKWLPNSTTT---CGLSPDSAILKLKAAANAVLQDK--------------------SLS---------RTEDSLRFESFSSPFSSQSASSTLAALSKKVSERS--LTPGQEHPPPASSFLSLASMTSSAALLKEVAARAAGSLLAEKSSLLPDDPLPLPPSEKKPEKVTPPPPPPPPPAQP---QSLELLLLPVPKGRVSKPSNSAPEEESGKPFQCPICGLVIKRKSYWKRHMVIHTGLKSHQCPLCPFRCARKDNLKSHMKVHQHQDRGETFQCQLCPFTSSRHFSLKLHMRCHQHFLRTEAKVKEEILDPDVKGSPHLS-DSGCLGQQREGGGTELVGTVMTSNTPERTGQGGAGVAPLLVKEEPKEDNGLPTSFTLNAADRSANHTKPKDPSEFVPN------SAAALFSQDISVKMASDFLMKLSAANQKEPMNLNFKVKEEPKEEETLSMPLPRSSYAFSPEPEVATPSISEDPLTPQEGKGNVLRRDMSAKAASELLMKLSAES-YKETQVVTVKEEPMEVDIQDSPASISPSRNVGYSTLMGREKTEPLQKLPEGRVPPERNLFSQDISVKMASELLFQLSEKVSKEHNHTKENTMRTTTSPFFSEDTFRQSPFTSNSKDLLPGEPVLHGRVSAPETDKIVLEAGNGLPSWKFSDQLFPCDVCGKVFGRQQTLSRHLSLHTEERKYKCHLCPYAAKCRANLNQHLTVHSVKLVSTDTEDIVSAVTSEGSDGKKHPYYYSCHVCGFETELNVQFVSHMSLHVDKEQWMFSICCTACDFVTMEEAEMKSHIGTKHTGDDRKTPSESNSPSSSSLSTLSDSANGKDDSDSSQKNKGGNNLLVISVVPGSQPSLNN--EEKPEKGFECVFCNFVCKTKNMFERHLQIHLITRMFECDVCHKFMKTPEQLLEHKKCHTVPTGGLKCPFCIYSTNRPAAMECHLKTHYKMEYKCRICQTVKANQLELETHTREHRLGNHYKCDQCGYLSKTANKLIEHVRVHTGERPFHCDQCSYSCKRKDNLNLHKKLKHAPRQTFSCGECLFKTTHPFVFSRHVKKHQSGEGPEEDRKGLSPASREPAGPGAPLLVVGGGRSLLSPLSVMSASQALQTVALSAAH----GSSSEPNLALKALAFSGSPLHLDKYRNSDVAHLIPLTMLYPRNHLDLT-------------FHPPRPQTAPPSIPSPKHSFLAYLGLRERAETV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q505G8-1", "uniprot_id": "ZN827_MOUSE", "id": "Q505G8-1", "name": "Zinc finger protein 827", "aln": "MPRRKQEQPKRLPSHVSRQDE--AEGDFSEGEQWYGNSSETPSEASYGEVQENYKLSLEDRIQ-EQSTSPDTSLGSATPSS-HTLELVALDGEVLRDSLQCQGHLSPGVSSVCDDDPPSSNKPLSSNLRRLLEAGSLKLDG---TANGRVESPVNVGPSLSFSPPSHHAQQLSVLARKLAE-------------------KQDQSDQFTPSNR-------FIWN--QGKWLPNSTTT---CGLSPDSAILKLKAAANAVLQDK--------------------SLS---------RTEESLRFESFSSPFSSQSASSTLAALSKKVSERS--LTPGQEHPPPASSFLSLASMTSSAALLKEVAARAAGSLLAEKSSLLPDDPLPLPSSEKKPEKVTPPPPPPPPTAQPP--QSLELLLLPVSKGRASKPSNSAPEEESGKPFQCPICGLVIKRKSYWKRHMVIHTGLKSHQCPLCPFRCARKDNLKSHMKVHQHQDRGETFQCQLCPFTSSRHFSLKLHMRCHQHFLRTEAKVKEEIPDPDVKGSPHLS-DSGCLGQQREGGGTELVGTVMTSNTPERTGQGGAGVAPLLVKEEPKEDNGLPTSFTLNAADRPANHTKLKDPSEYVSN------SAAVLFSQDISVKMASDFLMKLSAANQKEPMNLNFKVKEEPKEEESLSMPLPRSSYVFSPEPEVSTPSVSEDPLTPQEGKGSVLRRDMSAKAASELLMKLSAES-YKETQAVTVKEEPMEVDIQDSPASISPSRNIGYSTLMGREKTEPLQKLPEGRVPPERNLFSQDISVKMASELLFQLSEKVSKEHNHTKENAMRTTTSPFFSEDTFRQSPFTSNSKDLLPGESVLHGRVSAPETEKIVLEAGNGLPSWKFNDQLFPCDVCGKVFGRQQTLSRHLSLHTEERKYKCHLCPYAAKCRANLNQHLTVHSVKLVSTDTEDIVSAVTSEGSDGKKHPYYYSCHVCGFETELNVQFVSHMSLHVDKEQWMFSICCTACDFVTMEEAEIKTHIGTKHTGDDRKTPSESNSPSSSSLSTLSDSANGKDDSDSSQKNKGGNNLLVISVVPGSQPSLNN--EEKPEKGFECVFCNFVCKTKNMFERHLQIHLITRMFECDVCHKFMKTPEQLLEHKKCHTVPTGGLNSGQW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q17R98-1", "uniprot_id": "ZN827_HUMAN", "id": "Q17R98-1", "name": "Zinc finger protein 827", "aln": "MPRRKQEQPKRLPSHVSRQEE--AEGELSEGEHWYGNSSETPSEASYGEVQENYKLSLEDRIQ-EQSTSPDTSLGSTTPSS-HTLELVALDSEVLRDSLQCQDHLSPGVSSLCDDDP-GSNKPLSSNLRRLLEAGSLKLDAA-ATANGRVESPVNVGSNLSFSPPSHHAQQLSVLARKLAE-------------------KQEQNDQYTPSNR-------FIWN--QGKWLPNSTTT---CSLSPDSAILKLKAAANAVLQDK--------------------SLT---------RTEETMRFESFSSPFSSQSASSTLAALSKKVSERS--LTPGQEHPPPASSFLSLASMTSSAALLKEVAARAAGSLLAEKSSLLPEDPLPPPPSEKKPEKVTPPPPPPPPPPPPPPPQSLELLLLPVPKGRVSKPSNSASEEESGKPFQCPICGLVIKRKSYWKRHMVIHTGLKSHQCPLCPFRCARKDNLKSHMKVHQHQDRGETFQCQLCPFTSSRHFSLKLHMRCHQHFLRTEAKVKEEIPDPDVKGSPHLS-DSACLGQQREGGGTELVGTMMTSNTPERTSQGGAGVSPLLVKEEPKEDNGLPTSFTLNAADRPANHTKLKDPSEYVAN------SASALFSQDISVKMASDFLMKLSAANQKEPMNLNFKVKEEPKEGESLSTTLPRSSYVFSPESEVSAPGVSEDALKPQEGKGSVLRRDVSVKAASELLMKLSAES-YKETQMVKIKEEPMEVDIQDSHVSISPSRNVGYSTLIGREKTEPLQKMPEGRVPPERNLFSQDISVKMASELLFQLSEKVSKEHNHTKENTIRTTTSPFFSEDTFRQSPFTSNSKELLPSDSVLHGRISAPETEKIVLEAGNGLPSWKFNDQLFPCDVCGKVFGRQQTLSRHLSLHTEERKYKCHLCPYAAKCRANLNQHLTVHSVKLVSTDTEDIVSAVTSEGSDGKKHPYYYSCHVCGFETELNVQFVSHMSLHVDKEQWMFSICCTACDFVTMEEAEIKTHIGTKHTGEDRKTPSESNSPSSSSLSALSDSANSKDDSDGSQKNKGGNNLLVISVMPGSQPSLNS--EEKPEKGFECVFCNFVCKTKNMFERHLQIHLITRMFECDVCHKFMKTPEQLLEHKKCHTVPTGGLNSGQW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B762-1", "uniprot_id": "A0A8M2B762_DANRE", "id": "A0A8M2B762-1", "name": "Zinc finger protein 827", "aln": "MPRRKQEQPKRLPSHVDTVEDGGPESGSVEEDSWFGNTSDSPSESSYGDVQDELRVSPDNVPRPDHDTSAESSLGCPTPVQRASLELLGLDSGVLST----QDTLSSVVSSLYGDSSQALGKPLSSNLRRLLEAGSLKLEGGELAGRGTGRGQESPPVSLVLSPSSHHAQQLSALARRLANSSNNSGNSNSASPASVATVKQEPCDPYGPSNGPNSGSSGFVWVGVADKWPSTSCSAPSGSSLSPDSAIQKLKAAANAVLQDKNAVASSTSASSSSSSSSSSSSVTSSSMAALGTRSDDAVRFEPFASPFSPQSASSTLAALSKKVSERSQQQVGSSEHQPSAGSFLSLVSMTSSAALLKEVAARAAGNLLADKK----EPALVLGASEDVKPLLDRNQKVPTP------TQAMDLLLPTVPKGRAKPSSQAGSPEDGGKPFQCPVCGLVIKRKSYWKRHMVIHTGLKSHQCPLCPFRCARKDNLKSHMKVHQHQDRGETFQCELCPFTSSRHFSLKLHMRCHQHFPRPDLKVKEEPGTDTEEGEGLLMGDGGAAGDQAMNTDASTSPTVSQPDARLLASPAEP-SNHVQIKEEPQERDVSVMSPFALCRERPSSSSSSLDLSGLKSSPPGPGPTAASLFSPDITTKTATDLLIKLSAANQKEALKGPYCVKEEPQAEEPLNSQR-GPSYSFCQEGPPGTTKPREE-GSPMLGKSSLLSQDINVKVASELLMKLSENNKDACVQNVIVKAEPMEVDPPLDLASPS-SHLLGFSTSGPCEKKEPMVNLPDHLPRPQNDLFSQDISVKMASELLFKLSEKVSKAN-ENKDNASFGIHSPSL-DDRFRQSPFSTRSKSSSPAEAGSSSRVPQQDPEKVSSEPGNGLSQWRLNEQLFPCPVCGKVFGRQQTLSRHLSLHTEERKYKCHLCPYAAKCRANLNQHLTIHSVKLVNTDVEQIVTAVTNDGPELKNCPYYYSCHVCGFQTEFNAQFVSHMSLHVDKEQWMFSLCCSTCEYVGVDEAEMKAHISAGHAGLNSRSPLSETKSTSSSLSALSDSLNSSEGGDVAQGNEELKSLLAPPSSVGSQSSLGPGAEEKAEKGFECVFCNFVCKTRPMYERHLQIHLITRMFECDVCHKFMKTPEQLLEHKKCHTVPAGGLKCPLCIYSTNRPAAMEGHLKTHYKMEYRCRICQAVWANQAELERHTRAHRLGNHYKCEQCGYLSKTANKLIEHVRVHTGERPFHCDRCSYSCKRKDNLNLHKRLKHAPRQTFGCAQCPFTTTHPFVYSRHVKKHQGGEGSAEEGEARPGTPHPGLLERGGSSSGSGDSGSTSPLMNLSASQALQSVALSITSKQQDGTPTARYLSANGTLSTLAARYFDQYRNCDLAHLVPLTTLFTTRRFTFHSPSPSNPSPPFSAFWSNSSPQSPPSPTSLKHSFLAYLGLTERAKTI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************. :: .*. * : *:**:*::***:***:**:: ::* :: : ::.**.::***..** . :***:.**. ** *. **. ***: .*.. . .******************:. :..* .. . .* :**.********.***:**: **: * : *** *:* .** ..* :: ..******* ************* *:: *:::::***.*:****.****************** . ..** *.*.*****.******************.***:*. : .* .**. : *.* *:::*** .*.***.. .*::.. *:.*******:*********************************************************:********************** *.: ***** :*. * *... *:* . .:. *: .:: :. . . : :****:* : * . :*.:. :. * * .. :*: *** **:.* *:*:*:*********.:: : *****: *.*. .** *. * .:. *: .* **..:* :*:..*.********* :. .* * :* ****** . .* * *: :*:** **.**: ::*: *:.:****************:******* : ..*:*: ** : :* ******::.**. *.:. .*:. :.:*: *.****..*::.:***** *********************************************:******.**.*:**:***.:*.: *: ***********:**:*.******************:**::*::* ::***:*:**.: *:* : ::* .....:*****:**** *..:..* :* *: :.**. . ***.**. ***.***************: *:**************************************:***:. ", "identical_positions": 602, "similar_positions": 267, "identity": "41.69%" }, { "cls_id": "homologset.agr.MGI:2444810", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWQ0-1", "uniprot_id": "D3ZWQ0_RAT", "id": "D3ZWQ0-1", "name": "", "aln": "MAPSPQACASPLLLLLLPCLGAGPALVRGLPRPLENSEPHVIP---------SEPRTFDLFWEKLDNESSRHSGTPQAHAEG-PKRPADSPLGPALHGPKVAPGVVQGERLLRADDLQLARALTSQGWTGPPDSQELLETEAPEPHPMGAPHLTLVPTTPSFQLTVATLDTASQKPGGPAGQQPPR-DEGLMAKAKTH-TQALPWGYQGSPHILVPETGAVRTLVLGKQGGHEQGLQEAVQGPLLTQQDPATPEVGSTPPVEAPVEVKSTPEPGTQLDRALARSLPLPEGLPAEPSKKGGAGDTWEVSSLGPQPEQTDHHGGQDSPAPPPIPPAASDISDGHLRPAIASMNGVDPISPQRVRGAMEAPGTPKSFIPDLLNSAQAANGTESPMRALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLVKVTTQRALGQPPPPEPSASSMVPIPASSPPANATAPPLRWGPLRRVLSFSWELHVYGVGVLFLLPALLALVTLAAALAGPRLALVAAVLVLVASGLRSAYMLTDPYGSQARLGVRAGLVLYNLPFPLLLTALAALTLLGLGAGLPQPLQKPLLLGVVAPVHGAGLLATDLFSTSPVLNLLTQGLSCAWGASVALGTLCLCRRRLLEGPRGWDASPGPRLLAVAGSLGLLASGLQLAASLWLYPGPGREGRFSWAWWGVHFWLRLLELTWALALALAALAATRPRPPTEHACWAKLLRLACPAPTGKSEVPERPNNCYAGPSGVGTGGLDISKSLIRNAAGEGGLPATPGSGPWGSAASLGRGRPGGPGMSRGSVGPAPSLSELDLRPPSPINLSRSIDAALFREHLVRDSVFHRCGLRGLASSPPGGALRPRRGSQPDAELDGAGTSLLRGRCRSLSEVCLRTSLPQHVVNPPVGAAAAGTSGSSLDSFSKGSLKISWNPWRHGLSSVDSLPLDELPSTVQLLPPPTPAPAPAPARAGEPQGEGQPRCKSSESHSASSDTIEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PE13-1", "uniprot_id": "PRRT3_MOUSE", "id": "Q6PE13-1", "name": "Proline-rich transmembrane protein 3", "aln": "MAPSPQACTSPLLLLLLPCLGAGPALGRGLPRPLENSEPHMIP---------SESQTFDLFWEKLRNESSWHSGDPQARAEG-PKKPADPYLGPALHGPKAAPG-VQGERLLRADDLQLARAFTSQGWTGPPDSQELLEPEAPEPHPVRAPRLTLVTTTPSSLLSAAILSTASQKPGGTAGQQPARNEELIMVKAETHITQASPWDFQGSSHTPVPETDAVRTLVLGKQGGHEQGFQEAVQGPLLTQQDPVVPGVGSTP----PVKVESTPEPGAQLDLALVRSLPLPEGLPAEPPKTG-AGDTWEVSSLGPQPEQTDLLGGQDSPAPQPIPPSASDTSDGHLRP-VSSLNGADPISPQRVRGAMEAPGTPKSFIPDLPNSAQAANGTESPVRALQPDEAEDWPGRPQSHPPAPPVQAPSTSRRGLVRVTTQRALGQPLPPEPSASSIVPIPASSPPANATAPPLRWGPLRRVLSFSWELHVYGVGVLFLLPALLALVTVAAALAGPRLALVAAALVLVASGLRSAYMLTDPYGSQARLGVRAGLVLYNLPFPLLLTALAALTLLGLGAGLPQPLQKPLLLGIVAPVHGTCLLATDLFSTSPVLNLLTQGLSCAWGASVALGTLCLCRRRLLEGPRGWDASPGPRLLAVAGSLGLLASGLQLAASLWLYPGPGREGRFSWAWWGVHFWLRLLELTWALALALAALAATRPRPPTEHACWAKLLRLACPAPTGKSEVPERPNNCYAGPSGLGTGGLDISKSLIRNAAGEAGLPVTPGSGPWGSAASLGRGRPGGQRMSRGSVGPAPSLSELDLRPPSPINLSRSIDAALFREHLVRESVFQRCGLRGLASSPTGGALRPRRGSQPDAELDGAGTSLLRGRCRSLTEVCLRTSLPQHVMEPPVGAAAAGTSGSSLDSFSKGSLKISWNPWRHGLSSVDSLPLDELPSTVQLLPPPT--PVPAPARAGEPQGEGQSRCKSSESHSASSDTIEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FWE3-1", "uniprot_id": "PRRT3_HUMAN", "id": "Q5FWE3-1", "name": "Proline-rich transmembrane protein 3", "aln": "MASSPWGCVCGLLLLLLPLLGTGPALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEMPEKPVASPLGPALYGPKAAQG-AQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEG-QEGQWPPR-DEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVP----PVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGPLRRVLSFSWELHVYGVGVLFLLPALLALAALAAAPAGPRLALVAAVLVLVASALRSAYMLTDPYGSQARLGVRGGLVLYNLPFPLLLTALAALTLLGLGAGLPPPLQNPLLLGAVALVHGVGLLATDLLSTWSVLNLLTQGLSCAWGAAVALGTLCLCRRRLLDGPRGWDASPGPRLLAVAGALGLLASGLQLAAALWLYPGPGRVGRFSWAWWGVHFWLRLLELTWALALALAAVAAARPRPPTEHACWAKLMRLACPAPSGKSEVPERPNNCYAGPSNVGAGSLDISKSLIRNPA-ESGQLATPSSGAWGSAASLGRGPQGGPGLSRNGVGPAPSLSELDLRPPSPINLSRSIDAALFREHLVRDSVFQRCGLRGLASPPPGGALRPRRGSHPKAELDDAGSSLLRGRCRSLSDVRVRGPVPQHVVEAPDGAAAAAS-GSSLDSFSRGSLKISWNPWRHGLSSVDSLPLDELPSTVQLLPAPTPAPDSTAARQGDGQGEVQPRGKPGESRSASSDTIEL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.** .*.. ******* **:**** **:******** :** **.::**:* *: :* :*. :* ** *::*. . *****:***.* * .* *** :****:*:. :*:***** ******: ** ***: *:**::.*** * .* : .: *: * ** *.* :* : .*:::: . : * ..**..* *..:.:*: ** ***.*: :***.*** :*****..* ***.* **:* : ***:* * **.**** .* **.*..* . * :***** ** *:*:* ..:***.* * *.**: .* :* :::**.***********:********:**. :.. *.* ****: ********:************************::********** ****:***:.. **********************************************.::*** **********.******.********************.***************************** ***:***** ** ***. ******:** .***************:**************:******************:************:********* *****************************:**:**************:*******:*****************.:*:*.**********.* *.* .**.**.********** ** :**..***********************************:***:*********.*.**********:*.****.**:**********::* :* .:****::.* *****.: ********:*********************************.** * .:.** *: *** *.* *..**:*********", "identical_positions": 697, "similar_positions": 165, "identity": "70.4%" }, { "cls_id": "homologset.agr.MGI:2444812", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C078-1", "uniprot_id": "KKCC2_MOUSE", "id": "Q8C078-1", "name": "Calcium/calmodulin-dependent protein kinase kinase 2", "aln": "----------MSSCVSSQPTSDRVAPQDELGS---------------GGGSREGQKPCEALRGLSSLSIHLGMESFIVVT-ECEP------------------------GRGVDLNLARDQPPE--ADGQELPLE--------ASDPESRSPLSGRKMSLQEPSQGGPASSSNSLDMNG--------------------------------------------------------RCICPSLSYSPASSPQSSPRMPRR--PTVESHHVSITGLQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGARPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVP---------TLKPLSEDQARFYFQDLIKGIEY------------------LHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN-------EFKGSDALLSN--TVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIA------------EDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLP--------------SEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGN-PFEGSRREERSLSAPGNLLTKKPTREWEPLSEPKE--------ARQRRQPPGPRAGPCGGGGSALVKGGPCVESWGAPAPGSPPRMPPLQPEEVMEPE---------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88831-1", "uniprot_id": "KKCC2_RAT", "id": "O88831-1", "name": "Calcium/calmodulin-dependent protein kinase kinase 2", "aln": "----------MSSCVSSQPTSDRAAPQDELGS---------------GGVSRESQKPCEALRGLSSLSIHLGMESFIVVT-ECEP------------------------GRGVDLSLARDQPLE--ADGQELPLD--------ASEPESRSLLSGGKMSLQERSQGGPASSS-SLDMNG--------------------------------------------------------RCICPSLSYSPASSPQSSPRMPRR--PTVESHHVSITGLQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVP---------TLKPLSEDQARFYFQDLIKGIEY------------------LHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN-------EFKGSDALLSN--TVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIA------------EDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLP--------------SEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGN-PFEGSRREERSLSAPGNLLTKKPTREWEPLSEPKE--------ARQRRQPPGPRASPCGGGGSALVKGGPCVESCGAPAPGSPPRTPPQQPEEAMEPE---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96RR4-1", "uniprot_id": "KKCC2_HUMAN", "id": "Q96RR4-1", "name": "Calcium/calmodulin-dependent protein kinase kinase 2", "aln": "----------MSSCVSSQPSSNRAAPQDELGGR--------------GSSSSESQKPCEALRGLSSLSIHLGMESFIVVT-ECEP------------------------GCAVDLGLARDRPLE--ADGQEVPLD--------TSGSQARPHLSGRKLSLQERSQGGLAAGG-SLDMNG--------------------------------------------------------RCICPSLPYSPVSSPQSSPRLPRR--PTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVP---------TLKPLSEDQARFYFQDLIKGIEY------------------LHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSN-------EFKGSDALLSN--TVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIA------------EDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLP--------------SEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGN-PFEGSRREERSLSAPGNLLTKKPTRECESLSELKE--------ARQRRQPPGHRPAPRGGGGSALVRGSPCVESCWAPAPGSPARMHPLRPEEAMEPE---------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4V2C3-1", "uniprot_id": "A4V2C3_DROME", "id": "A4V2C3-1", "name": "calcium/calmodulin-dependent protein kinase", "aln": "MDLTDPLLITKSQQVNSQEVDFQKKTEDTFPSKFHKNKASCGLLAVNESRCTDHQLQCENNIVGLSLETQIAENSSINVSRELKPHDHTFPKDKQTFKQISDELRKSYENINKVQNIKKSQSVENFEKCSEINLANKCLYTNLNTSPKERNALDKQAMFIKFHSLELCTDKVCSLHIHENFCTDIHKCVVDSESNKPNKMKKCLDYESVKRYPCKVSNEPPQHNTASKPQILYETRPIYPNVPYSPYSTPFSSPRSSRRKPAFRESRRISIDKSGSFLQLNQYRLMEQIGQGSYGLVKLAYSEEDSTHYAMKILSKKRLLRQAGLMRRGPRKATS-----------PLDRVYREIAVLKKLDHPNVVKLVEVLDDPLEDSLYMVFELVKQGEVLRIP---------TDNPLSEKRAWSIFRESLLGLEYYTMLSSSAISLKRIFVYTVHHQKIIHADIKPGNLLLTEFGHVKIADLGVCN-------EFLGDDATISNGSTAGTPAFRAPETLIPGQNEYCGRAADVWALGATLYSLIFGNVPFLADSVPLLYEKIKQDSVKFPENHKVT------------ENLKSCIVQMLEKNPTQRITIPQLKTSKWVTSDGDYPLP--------------TEEENCCLVQVDDEDIDSVVRSIPKLDTLILIKTMLKKHSFGN-PFVKG-CSGTSSSLAG----------CSRIERFIR--------AGRSNSAPGSYHMSTARQPSSDTLLPSLMEHCSTQCNEGTHSFDY-------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P43637-1", "uniprot_id": "TOS3_YEAST", "id": "P43637-1", "name": "Serine/threonine-protein kinase TOS3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MVLLKEPVQPLPRSS----------------------------------------------------------------------LLYNNASNSSSRIKETRK-------VKLLYNPLTKRQILNNFEILATLGNGQYGKVKLARDLGTGALVAIKILN--RFEKRSGYSLQLKVENPR---------------VNQEIEVMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLEY------------------LHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEFPSYEEMLNGATSGITMEEYTDAKDLLKKLLQKDPDKRIKLADIKVHPFMCHYGKSDAASVLTNLETFHELKVSPPSSCKRVELVSLPVNSSFASLDSVYMENFDHNNLRTGADRNSTYSPSIYDANTLSPSAYHNIGSRESSYSSFSSFTSSTAFASQISIQDAPAIGDQQCLIGESGSSLRVNSCEFPQYTTMSPVGEYPFESTEASLSSTLTPVGNVPQRIKAHLVEGKSNSKDDLRIEADASLVFEASDAQRTRRRMSLYKL", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : *. *.. * : .*: :: . **:: : :*:*.** **** . .: *:*:*. :: :::* : . . * :** ::*: .* ***:* *:*:** . :*:*:* .:* * * . *: .:: . : : *:** :* * * * ****.***: . * :**:*:**. :: ... : : : ***** *** :: .. * *:*::*.*:*.::**: ** : *...* ...::**. .: : *. : ::*:*:* .** :.::* :: * . : ..* *:: . ::. . : .: : :. ::. : * .: . . : * .. . :. : : . * . *: . : . . ", "identical_positions": 94, "similar_positions": 151, "identity": "11.35%" }, { "cls_id": "homologset.agr.MGI:2444813", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BH86-1", "uniprot_id": "GLUCM_MOUSE", "id": "Q8BH86-1", "name": "D-glutamate cyclase, mitochondrial", "aln": "---------------MTISFLLRSCLRSAVRS--LPKAALIRNTSSMTEGLQPASVVVLPRSLAPAFESFCQGNRGPLPLLGQSEAVK-TLPQLSAVSDIRTICPQLQKYKFGTCTGILTSLEEHSEQLKEMVTFIIDCSFSIEEALEQAGIPRRDLTGPSHAGAYKTTVPCATIAGFCCPLVVTMRPIPKDKLERLLQATHAIRGQQGQPIHIGDPGLLGIEALSKPDYGSYVECRPEDVPVFWPSPLTSLEAVISCKAPLAFASPPGCMVMVP-KDTASSASCLTPEMVPEVHAISKDPLHYSIVSAPAAQKVRELESTIAVDPGNRGIGHLLLKDELLQAALSLSHARSVLVTTGFPTHFNHEPPEETDGPPGAIALAAFLQALGKETAMVVDQRALNLHMRIVEDAIRQGVLKTPIPILTYQGRSMEDARAFLCKDGDPKSPRFDHLVAIERAGRAADGNYYNARKMNIKHLVDPIDDIFLAAQKIPGISSTGVGDGGNELGMGKVKAAVKKHIRNGDVIACDVEADFAVIAGVSNWGGYALACALYILNSCQVHERYLRRATGPSRRAGEQS-WIQALPSVAKEEKMLGILVENQVRSGVSGIVGMEVDGLPFHDVHAEMIRKLVGATTVHM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A9W3-1", "uniprot_id": "D4A9W3_RAT", "id": "D4A9W3-1", "name": "D-glutamate cyclase, mitochondrial", "aln": "MENTQVLCGSFWDGMVPFSLLLRSCLPSAIRS--LPKAAHIRNISSMTGGLQPASVVVLPRSLAPAFESFCQGNHGPLPLLGQSEPEK-TFPQLSAVPDIRTICPQFQKYEFGTCTGILTSLEEYSEQLKDMVTFIMDCSFSIEEALEQAGIPRRDLTGSGHAGAYKTAVPCATIAGFCCPLVVTMRPVPKDKLERLLLATHSLGGQQGQPIHIGDPELLGIKPLSKPDYGSYVECRPGDVPVFWPSHLTSLEAVIGCKAPLAFASPPGCTVMIP-RDTVSPASRPTPQMVPEVHAISKDPLHYSIVSAPAAQKIRELESTIATDPGNRGIGHLLLKDELLLAALSLSHAHSVLVTTGFPTHFSHEPPEETDGPPGAIALAAFLQALGKEAAMVVDRRALNLHTKIVEDAVKQGVLKTPIPILTYRGGSVEDARAFLCKDGDPKSPRFDHLVAVERAGRAADGNYYNARKVNIKHLVDPIDDIFLAAQKIPGISSTGVGDGGNELGMGRVKEAVKKHIRNGDVIACDVEADFAVIAGVSNWGGYALACALYILNSCPVHERYLRRATGPSGEAGEQS-WIQALPSVAKEEKMLGILVQNQVRSGVSGIVGMEVDGLPFHGVHAEMIQKLVDVTTVPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z3D6-1", "uniprot_id": "GLUCM_HUMAN", "id": "Q7Z3D6-1", "name": "D-glutamate cyclase, mitochondrial", "aln": "---------------MPFTLHLRSRLPSAIRSLILQKKPNIRNTSSMAGELRPASLVVLPRSLAPAFERFCQVNTGPLPLLGQSEPEKWMLPPQGAISETRMGHPQFWKYEFGACTGSLASLEQYSEQLKDMVAFFLGCSFSLEEALEKAGLPRRDPAG--HS---QTTVPCVTHAGFCCPLVVTMRPIPKDKLEGLVRACCSLGGEQGQPVHMGDPELLGIKELSKPAYGDAMVCPPGEVPVFWPSPLTSLGAVSSCETPLAFASIPGCTVMTDLKDAKAPPGCLTPERIPEVHHISQDPLHYSIASVSASQKIRELESMIGIDPGNRGIGHLLCKDELLKASLSLSHARSVLITTGFPTHFNHEPPEETDGPPGAVALVAFLQALEKEVAIIVDQRAWNLHQKIVEDAVEQGVLKTQIPILTYQGGSVEAAQAFLCKNGDPQTPRFDHLVAIERAGRAADGNYYNARKMNIKHLVDPIDDLFLAAKKIPGISSTGVGDGGNELGMGKVKEAVRRHIRHGDVIACDVEADFAVIAGVSNWGGYALACALYILYSCAVHSQYLRKAVGPSRAPGDQA-WTQALPSVIKEEKMLGILVQHKVRSGVSGIVGMEVDGLPFHNTHAEMIQKLVDVTTAQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IQ88-1", "uniprot_id": "A0A0R4IQ88_DANRE", "id": "A0A0R4IQ88-1", "name": "D-glutamate cyclase, mitochondrial", "aln": "-----------------MVLLKCARVTNFLQRAVGTKGLTYSTRARKKPGFQQANVVILHKDLADDFEAFCRANSSPLPLLYRSKCGEWSAGPLATASDIREDCPEYCVFENGRLMKKVSSLSSFTSELEHMVTFYLGCSFGFESALTAAGVPVRNVEQGRNVSMYKTSVPCIKAGQIHCPMVVTMRPVPEDKLDATAQCTHAIPLAHGGPVHIGDPKLLGIRDLSRPDYGDPVDARPADVPVFWACGVTGVEAVKSCKSALAFTHSPGCMFITDQKAEAISPLSLEPAQRPLTFRISQDPQHYSMASERAVQQIRAIEELAVEDPGSRGIRALFLQDELLKACLSLSHSSSVLITTGFPTHYMHNPPEETDGPPGALAMAAMLQALHKEVVIVTDQRALEMNQHIMQDAVEKGVIKSAVPVISFQSNGPDSALHFLCGDGDPTKPRFDHLVAIERSGRAADGNYYNMRGVNIKHLLDPIDELFTAASTIAGITTTGIGDGGNELGMGKVKAAVKAHMPNGKLIACDVAADFAITAGVSNWGGYAVACALYVLNLCPVHQRYLQRGLGLSPTPEQQSKWAECLPTVAKEEEMLRILVKYGVRSGKTANLGLEVDGLTFHPYHSDIIQRLRHLTYD--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : : . :: * . : :: *.:*:* :.** ** **: * .***** :*: : .: .: * *: :: * ::**...:.:*:.**:* :.***.:*.** **:* *: : :*:*** . . : **:******:*:***: . :: :* *:*:*** ****. **:* **. : . * :*****.. :*.: ** .*::.***: *** .: : .. * * .. **:** ***:.* * *::* :*. ***.*** *: :**** *.*****: ***:*******: *:***********:*:.*:**** **..::.*:** ::: :*::**:.:**:*: :*:::::. . : * *** :*** .********:**:********** * :*****:****::* **..*.**::**:**********:** **: *: :*.:***** ****: **********:*****:* * **.:**::. * * . :*: * :.**:* ***:** ***: **** :. :*:*****.** *:::*::* * ", "identical_positions": 276, "similar_positions": 176, "identity": "43.33%" }, { "cls_id": "homologset.agr.MGI:2444815", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5TGI4-1", "uniprot_id": "SAMD5_HUMAN", "id": "Q5TGI4-1", "name": "Sterile alpha motif domain-containing protein 5", "aln": "--------------------------------------------------------------------------------MCTNIVYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQDANAAGLYFT--------------------------------LEPQPAPPGPPADAVPTGRRGEPCGGPAQGTRGD--------------------------------SRGHTTAPRS-----------------------------------RELVSYPKLKLK-------IMIRDKLVRDGIHLSKP------------PYSRKVP--MAGILEYLMNWPKSS----QSR----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3V1H9-1", "uniprot_id": "SAMD5_MOUSE", "id": "Q3V1H9-1", "name": "Sterile alpha motif domain-containing protein 5", "aln": "--------------------------------------------------------------------------------MCTNIVYEWLRALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVHRLREQDAAAAGLYFT--------------------------------LEPQPVPPAPLVEAVPPGRRGEPCGSSAQGTRGD--------------------------------PRGQPGAPCS-----------------------------------RELVSYPKLKLK-------IMIRDKLVRDGIHLSKP------------PYSRKVP--MAGILEYLMNWPKSS----QNH----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ABZ6-1", "uniprot_id": "A0A8I6ABZ6_RAT", "id": "A0A8I6ABZ6-1", "name": "Sterile alpha motif domain-containing protein 5", "aln": "--------------------------------------------------------------------------------MCTNIVYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVHRLREQDAAAAGLYFT--------------------------------LEPQPVSPAPLVDAVPPSRRGEPCGGSAQGTRGD--------------------------------PRGQPSAPRS-----------------------------------RELVSYPKLKLK-------IMIRDKLVRDGIHLSKP------------PYSRKVSGISSSLLGGVLIRPVSVCFVVRSGIT--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4KGJ9-1", "uniprot_id": "A0A0B4KGJ9_DROME", "id": "A0A0B4KGJ9-1", "name": "Sterile alpha motif domain-containing protein 5", "aln": "MKATSSSSCSSAASSCNQPEPLATGVGSSGVSGASGASGASGASTSTKPQRLNKVSFAPLDLPFPSGATXYANANASTSMPHHNIVCEWLRTIGLAHYGESFLENGYDELEICKQIGEIDLDAIGVDNPSHRGKLLKSVRMLREKGAAIVYVLINDPKALSSSNEILASDCDTPVTMKELEAVMKRHLEADGIRLTAHPYSTPEGKRGYLEGLAAHYSKQINMPYDDVLDAIEQVRLSKWKERHVRISTGHTLSRRMAGPSCSGTGLVSSSVMPTSHSQPLYVPGKYLPSSCLSNREENEIYSYTQNDLANRMARNAIDSKSALNLNGMQHSYPGARTNFFYNFSATEGRNKHKQRRTVFHRFLQGLRQSGDELNATEGMQLKTNERLRNCSTMKRPEPHQDFEKTIQRLKTQKAAQKKPASAPMEMAIHDRNKEVAHTHVNEMPLNNYTKHP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCW5-1", "uniprot_id": "Q9VCW5_DROME", "id": "Q9VCW5-1", "name": "SAM domain-containing protein", "aln": "--------------------------------------------------------------------------------MCGRAVRDWLVLLTMEKYIGKFLERGYDSIERCKLIIVSDLIMLGVDNPAHRKLLLEGVRFLVNAPEQFICK--------------------------------------EPCELHEEIELKLDPDVELFASLKCLENVDF----------------------------------LETPVPYS--------------------------------------LTSPQKTLT-------TRDSCKWNVKGVDQLPS----------------------DNIFN--------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :** : : :* .*::.***.:* ** * ** :** *:** :*:.*: * : : . . . . . * : .: * .*:. . :: ", "identical_positions": 25, "similar_positions": 33, "identity": "5.52%" }, { "cls_id": "homologset.agr.MGI:2444817", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LCY4-1", "uniprot_id": "A0ABK0LCY4_RAT", "id": "A0ABK0LCY4-1", "name": "", "aln": "MTVFLSLMGEQKVSRQ--FKQCHRTASWAKSKLFRCVLFFSRLSSMFLRQLGKNIKFGQRPSNVIPMKKAGSADASSEEDFVLTSPMEIVTQQDIVLSDTENKSSDTPSSSSPLNLPEAGSDMEEKVAPVKPSRPKRHISSAGTIESVNLDAIPLAIARLDNSAAKHKLSVKPKNQRVSRKHRWLAQDRQNA-----PGSFESQSSLDQNGQLGEDKHIGQGEEPEPLESHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRLWEESLRQELLEEEEE------------EAEEVGLLLQAGKAPPEEGPQSGLEEQRGSEQELGEADDPTRLEAEERRREQEKAERQAEKLRQREEAERQEEELRQREEAERQAEELRQREEAERQEEELRQREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAKRQEEELRQLEEAERQEKLRQREAQKQE-EEELRQREAERHEKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEE-AKHIEELKGREKEAPEPLVEEGSQGPEGESQPWLTDDADQQSPLQRDLEKPGERE--DLVSAGQRDIPEDQRGEVEMAIEPVEQSGDWGAHFGGVDGVDVEGKEASQIDNPQPQERQKEGTPAREE-KEATAADIDRKVEELRWQEVDER---PRPYTFQVSSGSRQILFPKVNLSPVTPAKDASLAPAAQEPPAPRG-----AASHALPSALSIPHTAILVTGAQLCGPAVNLSQIKDSACKSLLGLSEEKRPADVPTVEP--------RAGGGKSKPAPES-----PSNAVALAEWASIRSRILKNSEGDQRG-DREPARVGDEPAPRARCDSRGNVRKTPPVNAKFSIMPAWQKFSDSG--AETFKQSTDGESVRKKPGPAPSEETTPTPQPLPAGAPELQKNLEKQEVSQEPPDTTDGCKFAKDLPSFLVPSLPSP-QKAASRTESTTSLDSETTSDVGSPD---PAMPGGEEKASPFGIKLRRTNYSLRFHCDQQAEQKKKKRHSSTGDSVDGDAPP-----GERNPEATFLKHGPSLPQERRPALAPRRDSAESHPSGHCVAAAVHPGLPPASGQTPAPEQDKVASKTPLSMQKPALAPKPAS-QTPPSSPLSKLSRPHIVELLTRRAGKLDSEPSEPAKENQESRDSQPPSPSLLEEPKGQKRDEKD-VLEKKPASPPLPSSQQERPSLTPETGRKEKPMLQSRHSLDGSKLTEKAETAQPLWITLALQKQKGFREQQATREERKQAREAKQAEKLSKETASVSQQPGSSRVSKAGSVHKPAAPSEE-KKPETAVSKLQRREQLKKSNTLPTSVTVEISDSAPSAPLVKEVTKRFSTPDAAPVSTEPAWLALAKRKAKAWSDCPQIIK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5PR69-3", "uniprot_id": "CRACD_MOUSE", "id": "Q5PR69-3", "name": "Capping protein-inhibiting regulator of actin dynamics", "aln": "-------MGARAFSHDSIFIPDGGAESEQTVQAMSQDNILGKVK-TLQRQLGKNIKFGQRPSNAIPMKKAGSTDASSEEDFVLTSPMEIVTQQDIVPSDTENKSSDTPSSSSPLNLPEAGSDMEEKVAPVKPSRPKRHLSSAGTIESVNLDAIPLAIARLDNSAARHKLAVKPKNQRVSRKHRWLAQDRQNE-----PGSFESQSSLDQNGQLGEDKHIWHGEEPEPLESHEEKRLHEEYWRELEAKCKRQKAEAAEKRRQEEQRRQALERRLWEESLRQELLEEEEEGEEEEEVKEEGEEGEEVGLQPRAGKVPPEEGHQSGPEEQRCTEQELGGADDPARLEAEERRREQEEAERQAEKLRQRE-AERQEEEQKQRE--------------AERQEEEARQCEAERQAEKLRQREAERQEEEARQREAERQAEKLRQREAERQEEELRQREEAERQEKLRQRDAESQE-EE-LRQREAE---------------------RQRAQEEDAKGMLQEEEEEAKRIEELKG--KETPEPLVEEGPQSPEGESQPWLTDDADQRSPLQRDLEKPGEREREDLESAGQREIAEEPRGEGE----PAEQSGDLDAHCGGVDG---EGKETAQTDSPQPQERQMEGTPAPEE-NEATAADIDRKVEELRWQEVDERQTMPRPYTFQVSSGSRQILFPKVNLSPVTPAKDASLAPAAQEPPAPRG-----AASHALPSALSIPHTAILVTGAQLCGPAVNLSQIKDTACKSLLGLSEEKRPMDVPTVES--------RAGSGKSRPAPES-----PSNAAALAEWASIRSRILKNSEGDQRG-DREPARAGDEPVPRARCDSRGNVRRTPPVNAKFSIMPAWQKFSDSG--AETFRQSLDGESGRKKPGLAPSEETAPQPH-----------AAAQQEVSQEPPDTTDGCKFAKDLPSFLVPGLPSP-QKAASRTESTTTLDSETTSDVGNPD---PAMPGGEEKASPFGIKLRRTNYSLRFHCDQQAEQKKKKRHSSTGDSVGGATPATGSVSGESEPEATFLKHGPSLPQERKPALSPRKDSAESHSSGHYVAVAQS-GLPPASGQTPAPEQDRAVSKMP-SMQKPALAPKPAS-QTPPSSPLSKLSRPHLVELLARRAGKLDSEPSETAKE---SSDNQPPSPSLPEELKGQKRDEKD-VPEKKPASPPLPAGQQERPSLIPETGRKEKPVLQSRHSLDGSKVTEKVETAQPLWITLALQKQKGFREQQATREERKQAREAKQAEKLSKETVSVSLQPGSSRASKTAPVHKPAAPSEE-KKPETAVSRLQRREQLKKSNTLPTSVTVEISDSAPSAALVKDVTKRFSTPDAAPVSTEPAWLALAKRKAKAWSDCPQIIK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZU35-1", "uniprot_id": "CRACD_HUMAN", "id": "Q6ZU35-1", "name": "Capping protein-inhibiting regulator of actin dynamics", "aln": "-------MGTRAFSHDSIFIPDGGAESEQTVQAMSQDNILGKVK-TLQQQLGKNIKFGQRSPNAIPMNKANSGEASLEEDLFLTSPMEIVTQQDIVLSDAENKSSDTPSSLSPLNLPGAGSEMEEKVAPVKPSRPKRHFSSAGTIESVNLDAIPLAIARLDNSAAKHKLAVKPKKQRVSKKHRRLAQDPQHE-----QGGLESRPCLDQNGHPGEDKPTWHEEEPNPLDSEEERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGE-----------------------GQEPPLEAERAPREEQQRS------------LEAPG----WEDAER-----REREERERLEAE------------------------EERRRLQAQAQAEERRRLEEDARLEERRRQEEE---EGRCAEELKRQEE-----EEAEGWEELEQQEAEVQG-PPEALEETGEG--------------------RRGAEEEDLG---EEEEEGQAHLEDWRG--------------------QLSELLNDFEERLEDQERLKPEGQRE-----HSEEPGICEEQNPEAE---RRREQQGRSGDFQGADRPGPEEKREEGDTEPLLKQEGPVEAAQPPVERKEAAALEQGRKVEELRWQEVDERQTMPRPYTFQVSSGGKQILFPKVNLSPVTPAKDTGLTAAPQEPKAPKAS----PVQHALPSSLSVPHTAILVTGAQLCGPAVNLSQIKDTACKSLLGL-EEKKHAEAPAGENPPRGPGDARAGSGKAKPRQES-----PSSASALAEWASIRSRILKNAESDPRSSERDQLRPGDESTPRGRCDSRGNQRKTPPVNAKFSIMPAWQKFSDGG--TETSKQSTEAESIRKRPMLGPSEETAPQPP--PAGVRELGKGPEKSEMHREPADTTEGCKFAKDLPSFLVPSLPYPPQKVVAHTEFTTSSDSETANGIAKPD---PVMPGGEEKASPFGIKLRRTNYSLRFNCDQQAEQKKKKRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSAEPSSS-RSVPVAHP-GPPPASSQTPAPEHDKAANKMP-LAQKPALAPKPTS-QTPPASPLSKLSRPYLVELLSRRAGRPDPEPSEPSKEDQESSDRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQQEKPSQTPEAGRKEKPMLQSRHSLDGSKLTEKVETAQPLWITLALQKQKGFREQQATREERKQAREAKQAEKLSKENVSVSVQPGSSSVSRAGSLHKSTALPEE-KRPETAVSRLERREQLKKANTLPTSVTVEISDSAPPAPLVKEVTKRFSTPDAAPVSTEPAWLALAKRKAKAWSDCPQIIK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RG44-1", "uniprot_id": "CRACD_DANRE", "id": "Q5RG44-1", "name": "Capping protein inhibiting regulator of actin dynamics", "aln": "---------------------------------MSQENVSDKVR-NIQKQIGHNIKFGQRPP---SLRKSEGDEGSSDEEEVPQSPLRVLAQVENEPPETSAKEK------------SVSHDTVQHRTPVKSPRTKRPPP-PGTIESINLDAVPQSVPRLDNTAAKHKLSVKPKNQRVSRKHRRFTQEFHEDDFSEIQEEFEKDEEVFDSSREDYGIIHGSKEDYEPTEKSQRQRFHEEEKEHLEIK----KREQEEERKMEKHRRMIEEQRLEEEKRRR---QEEE-------------------------RLQKVEEERKQREEEERK---------------------------------KREEEERRREE------------------------EERR----LRHEEERKRQEE----EERMKKEEE---ERKRAEEERRQQE--------LLAERLRLEEERKREQEE-----------------------------RRRKEEEEAE---------KRRIQELQE------------------------------------KRLREE------------EHRIREEER----------------------------CRQEEAERKRLEEEERKRQ---LQEEKAGSTDPEWKRKAEELRWREMEER---QRPFTFKVSSGEKQILFQKVNLTPVTPATGQQGETTAETWEGAKASSPGGPDSPTLSSSLYVPHTAILVTGAQLCGTAVNLDQIKDTACKSLLGLSEGKKAMGTPPSKSKTS----PDRKSGKTKSVFESSLSTDQSNAAVLAEWASIRSKIFKGAEEGKYPEYTDQSRRPTSEDLNTVPFSHTNLRKTMSASAKFSITPARKKFADSNRNSEIFGQEEGVKTESAFTETSPVQKELPSLG-----------TKVQSRGSKLVRIADEECMFAKDLPSFLVPSPPHG-SPKSQRSESGSPIQAESEDSDTKDEDGEQKAQGGDEQPSPFGIKLRRTNYSLRFHNEQSAEKKKKR--YSAGDSFEGVPVP---------LTAIDQDSDNSTLSEKSSPISPQQENIEFQTTVAPSKESRS-KFSRSTLPLARTEGDNMSPKPP-LYQKPATSPKPSEGATPLLSPLPKPGRRTSGDTISQRTGEAEQVATE-----QGSDHKGGVTASGPSQKSGQ--GEED-VKEKKSFFPSISIPWREKTDRRTELIKKEKPSLQARHSLDSSRSQDK--ETGPLWITLALQKQKGFREQQQNREERRNQREAKLAEKQARDRESAGSSPTEDKGNGSSSIISKHQTADENKRPDTLLARFERRDNLKKANTLPSSVTVEITDSTPSPPATKDVTKRFPPGDTTQVSTEPAWLALAKRKAKAWSDCPQIIK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .:: : :*:*:*******.. .:.*: . :.* :*: . **:.:::* : .::. *.. .. : :: :***..*.** . .*****:****:* ::.****:**:***:****:****:*** ::*: :. :*. : :..: . . *: :* :. :.:* :*: ..** * * * *:*: *::* *:** **. *: :** : * : **:. . :** ** . * ** * : *: :: * ** ::* * * .* .**:* *.*. .: . : *: :**: :::: : . *. : * *: . :* .: . :* : * :: : **.*****:*::** **:**:**** :**** ****:*****.. .:.: ..:. . . :*.*:* :**************.****.****:******** * *: .*. : .**::. ** *.* .*********:*:*.:* . : * . . *: * *:* ...***** ** :**:*.. :* *. :: . .* :: * :.. : : : * ***********. * . ::* :. ::*: .. . : **:*:.****************: :*.**:***: *:*** . . . . . . * .*: . :.:::. * .: : . :: . .* *. * * **** :***:. ** ***.* .* : :::*:*. : .:* * . :.. .: .** .*:: . *:*. *.:. :*:.. .* :**** **:*****.*: :* : ****************** .****:: **** *** ::: *.. .* .. . :..: . .:* *:*:* :::::**::***:****:******:**:*... .*:*****.. *:: **************************", "identical_positions": 388, "similar_positions": 327, "identity": "27.79%" }, { "cls_id": "homologset.agr.MGI:2444818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEN0-1", "uniprot_id": "MILK2_RAT", "id": "D3ZEN0-1", "name": "MICAL-like protein 2", "aln": "---------MAAIKALQEWCRQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFNALRKENIYENNKLAFQVAEEQLGIPALLDAEDMVALKIPDRLSILTYVSQYYNYFHGRSPIGGMAGMKRPSSDSTEELSGKKKVPSQP----------------------AKLSSPVPTQRLPLSPARTNPVVQRNEGVSERPSPKAAPGTVG--------------------------SSVSSICGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSSTLHSGAYRATGEPGVFVCTHHSSEAVSVSPKLSNLASRQPGGGIADTRPIGVSQKVLETNGEATPLRARTAAWEHAGGNRAAKGFVQTELTPPA----TSRVHVGSPAGPRLPMSTVTTTSANSKATTHVTNSSPVGWSSSAQSSTGTSGSRPVVSPSALGAHLSVPQGQAAS--KGVKTQLNSSTDSSSTAPTPAWTSSSSRTQQAREKFFHNLSPAPAPAPASSSSSHASRVPTVVTAPSGKVSPLVNTSTSKVPSATVVTVPTSKASTVVTAPTSKAPTVVTVPISKAPTVVTAPTSKVSTVVTVPTSKASTVVTAPTSKASTVVTVPTGRGHVVVNTSASKVSGVVDNPAQESSREQALSVLRKALPGLTRAGSQAPSRSSPATSSVLITLPKNEVPPKVPSAK-LSHSTTQAFSPTPKMEPTAPLSVGSTSWTSVSLQAGKKSPGISPGIGKTSAVSRPQAEVKGTSGPGPTS--------QEGQEEGPEGWRARLKPVDKSIPSARALEQKEP-VLAEPRAGDTPRKASSSSDSSIHITLTPIQQKRTPCLADSGSSLAAPSP-PSRRKKLVVPPTLDVSADWLQPELKKQDDQTRSCK-EKTATWGTRESSAILDNDLVS--PDEAVTSPVRLHPNYISQEELQRQLQDIERQLDALELRGVELEKRLRAAE----GDASEDG---------------LMVDWFRLIHEKQLLLRRESELMYKSKDQCLEERQLDLQGELRRLMEKPEGLKSPQDRKREQELLNQYVNTVNDRSDIVDNLDEDRLREQEEDQMLESMIQNLGLQ----------RKKSKSFLSKIWSSKSKSGQT------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TN34-1", "uniprot_id": "MILK2_MOUSE", "id": "Q3TN34-1", "name": "MICAL-like protein 2", "aln": "---------MAAIKALQEWCRQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFSALRKENIYENNKLAFQVAEEQLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGIKRPSSDSTEELSGKK-GLSQP----------------------AKLPSPAQTQRSPLSPARTNPVVQRNEGGSQRPSPKAAPGTAG--------------------------SSVSSICGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSSTLHSGAYRATGEPGVFVCTHHSSEVTSVSPKSSNLASRKPGGVTADTRPFGVSWTVQEANGEGTPLRVRTAAWEHAGGNTTAKGFVQTELKPPS----TSQVHVGSSAGPKLPTITVTTTSVTSKALTHVTNSSPIGWSSPAQSSPANFNSRPVVSPSARNTHLPGSQGQTAS--KGVKTQLNLNSESSNTAVTPAWTSSASKTQQAREKFFQTPPSAPAPASAPAP-APTSKVPTVVTVPTSKVPNVVTAPTSKVP--TVVTVPTSKVPTVVSAPTSKVPTVVSAPTSKVPTVVNSTNSRVTTVVNAPTSKVPTVVSATNGRVPTVVTAHTGRVPAVMNTSASKVSPVVDAPAQESSREQALSVLRKALPALTGSGTQAPNRSFPATSSVLVTLPKNEVPQKVPSDK-LSALTTQTPNFTIKLEPSAPVNVGN---TAVFLQAGKKSPSISPRVGKTSVGSRPQAEVAGVKGPGPIS--------QEGQEEGPEGWRARLKPVDKKTPAGRSLEQKEP-VLAEPRIGDTSRKASSSSDSSVHITLTSIQHKRKPCPAGSGPSPAALSPSPSHRKKLAVPPSLDVSADWLQPEPKKQEDGTRSCKEEKSPTRWSRERSAVLDSGLAP--PGEAVTSPVRLHPDYIPQEELQRQLQDIESQLDALELRGVELEKRLRAAE----GDASEDS---------------LMVDWFRLIHEKQLLLRLESELMYKSKDQRLEEQQLDLQGELRRLMDKPEGLKSPQDRQREQELLSQYVNTVNDRSDIVDFLDEDRLREQEEDQMLENMIQNLGLQ----------RKKSKSFLSKIWSSKSKSGQA------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IY33-1", "uniprot_id": "MILK2_HUMAN", "id": "Q8IY33-1", "name": "MICAL-like protein 2", "aln": "---------MAAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRASEDSEEEPSGKK-APVQA----------------------AKLPSPAPARKPPLSPAQTNPVVQRRNEGAGGPPPKTDQALAG--------------------------SLVSSTCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTSHLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEAN------KARPSAWEPAAGNSPARASVPAAPNPAA----TSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAP-CTAAAASHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRTQQARNKFFQTSAVPPG-------------------------------------------------------------------------------------------------TSLSGRGPTPSLVLS----------------------KDSSKEQARNFLKQALSALEEAGAPAPGRPSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASALPPAGRRNLAESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDGPAGWRANLKPVDRRSPAERTLKPKEPRALAEPRAGEAPRKVSGSFAGSVHITLTPVRPDRTPRPASPGPSLPARSPSPPRRRRLAVPASLDVCDNWLRPEPPGQEARVQSWKEEEKKPHLQGKPGRPLSPANVPALPGETVTSPVRLHPDYLSPEEIQRQLQDIERRLDALELRGVELEKRLRAAE----GDDAEDS---------------LMVDWFWLIHEKQLLLRQESELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDRSDIVDSLDEDRLREQEEDQMLRDMIEKLGLQ----------RKKSKFRLSKIWSPKSKSSPSQ-----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IEN7-1", "uniprot_id": "A0AC58IEN7_DANRE", "id": "A0AC58IEN7-1", "name": "", "aln": "---------MAAIKALQQWCKIQCEGYRDVAISNMSMSFRDGLAFCALIHKFRPDLINFESLSKDNVYYNNHLAFRVAEDHLGIPALLDAEDMVALPVPDRLSILTYVSQYYNYFHGRSPIGGVGGIKRHAEDSKEVPSEKKNLPVVAKNHNLKTNTENRPPQSEMPKIINRPPSLNIQKSAPEKHAQATPARQTGTDRQKSPGPKCVQAPITPLRARSPQPHREAEKKSVLVETSNKTGTLNSECAVCGNHVHLVQRHLVDGKLYHRSCYKCSVCYGTLKSGAYKLGSDTGSLVCTIHQHGQNGFKPTVKPFKS---------------------------------------SGFTVSDLVAKSEREDQS----PSQRYISVLSAP-------------IKAVPRPVELS---------------------------------------------------------LAQQSWTSSAQRTQAARQKFFQSCSPATE-------------------------------------------------------------------------------------------------LQPNTKPPSGPAEPS------------------------SLKVQE----KEGNRALANGNRLHEGNANNNNALNSDPRAKSQVKISCSSAK-VSTWRQELHVRDSKGRSSYQAAPSS---PAIISSGGGMNGKESLYLSAISKERSRPPSLLQTTAKASAN--------DVQSYDAPADWRSKPK----AAPNGPRLN----------RSPDIAKDVALMCGENKDLKVQ----DSQAFMSNHSKVKTGACTAPGCNSDCSLASCVSPSTSCNKPSSPKQ-PRCRSAT-------SSYDNGNILCNDSLL----HEARSPT-TKTCYITPEQISKELQDIENNLNDLENEGVELEWKLRVYEEEGHGDILMDP---------------LMVDWFNLIRKKQSYIRRESELMYIARTQDLEEQQPGVEGELRRLINKPEHFKTLNEKKRETELLNRLMKIVNDRNAIVEGLEEDRIREEEEDQQLNEMMQRLGLQK--------FKNKRKSSFSKLFRRRSKKASMGE----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU34-1", "uniprot_id": "Q9VU34_DROME", "id": "Q9VU34-1", "name": "", "aln": "MSDRRGTKVGTGTKALEYWCRVVTQGYNGVKVENMTTSWRNGLAFCAIIHHFRPDLIDFDRLKADDIYENNDLAFTTAEKYLGIPALLDAADMVSYEVPDRLSILTYLSQFYKVLGKSLKHPKPEEPLGEESEPPQKVMHIVGMPRRDK------------------CQKCNLPVFLAERVLVGKRAYHRTCLKCARCSSLLTPGSFYETEVN---------------------NIYCCETCPDEESEPESDILKLKTTTTDSPNDKQMVAQSSDYSEAEDKQEDLEDNDIRTTDKPENFQPPSNKDEQNNELTINPVNPILSEERKISFIPLDEEDGGLIEQYNKSTTPVKPAIPEKPKVSTLPLDDEQHAGVEQNNDLAVSPENDIPKEKLKISSVSIYLEDDRLVVDAIHPDNLDKQEALNNTSDALIPESQEAPIPENNTQVAIKPEDHISPRKENKIFSNTESCSKQEGVLPKQMDLESPKDKVIETKASETDYPEDLNP----------------------------------------------------------------------------------------FKDDDSSKGANPFDSSDDE----------------VELLKAIPAQQSKGKVVPPRPPPPKIGLSSISNPSEKPHSSPTLSHGKKMPMPTPRISISKTQTPAKPMTHQGQKSSISSSSSEHLNSIRTFDRGADDRGSSISLPSANGPRKPLRASVGSPLRSEESSP--TTSLSSITSPMRKKRQAPLPPIQTDFDSDPGFSKLSDEQKALLHTQLKAPNLGDSTRRLIPLDQSLLSDEATESSNYDESLSTSNADEEVNVVYRRILVPPTQPENTVERSKEDQKSPIVYNDFDRNVSPLGHNKSTHGKWKRRKG-PAPAVPIPPRKVLQRLPLQEIRHEFEIIAVQQLGLEKQGVILEKMIRDRCERSLDATDTDGPESAEVLTNSKEVEDLILQLFELVNEKNELFRRQAELMYLRRQHRLEQEQADIEHEIRVLMGQPEHNKTDSDKAHEEVLINRLVKVVEMRNEVIDSLETDRVREAREDMSIKNRLHIYNSEREEPPAHPRSADKSSKKLSKKERKKLKEENKLGKGKKSDLDKDVDESEQAPALEKVKKKRNLFFLKM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :**: **: :**..* : **: *:*:******::*:.*****:*. * :::* **.*** .**. ********* ***: :*********:**:*: : .:. : . . : . * . : . . . . ..: :: .*. :: :.. : .. .: . : . . . : : . : : .: . .. : .::*.:.. . . . : .. * . ... .: . . . ... .. . * . * : . . . :: :. : . . . : . .. . : . . . * . . . * :. ::: :::: * . ** .** ** :* . * *::: * *:.:*: :* ::**** : : **:.* .:: *:* *: :** *: .:: :* *:.: :. *: *. ::: *: **:** .** :.. :. . : .* . :** : *. ", "identical_positions": 107, "similar_positions": 193, "identity": "9.26%" }, { "cls_id": "homologset.agr.MGI:2444823", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZM22-1", "uniprot_id": "D3ZM22_RAT", "id": "D3ZM22-1", "name": "Solute carrier family 41 member", "aln": "-----------------MSSKPE------------------------------------------------PKDIHQPNG-TGPTPSPCSSD---------------------------GPGREPLAGTS---EFLGPDGAGVEVVVIESRANAKGVREE-----------------------------DALLENGSQSNESDD----------------------------------------VSTDRVPAP--------------PSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGQMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELTHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEPTPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVNWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJA2-1", "uniprot_id": "S41A1_MOUSE", "id": "Q8BJA2-1", "name": "Solute carrier family 41 member 1", "aln": "-----------------MSSKPE------------------------------------------------PKDIHQPNG-TGPTPSPCSSD---------------------------GPGREPLAGTS---EFLGPD--GVEVVVIESRANAKGIREE-----------------------------DALLENGSQSNESDD----------------------------------------VSTDRGPAP--------------PSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGQMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELKHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEPTPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVJ1-1", "uniprot_id": "S41A1_HUMAN", "id": "Q8IVJ1-1", "name": "Solute carrier family 41 member 1", "aln": "-----------------MSSKPE------------------------------------------------PKDVHQLNG-TGPSASPCSSD---------------------------GPGREPLAGTS---EFLGPDGAGVEVV-IESRANAKGVREE-----------------------------DALLENGSQSNESDD----------------------------------------VSTDRGPAP--------------PSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELNHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEQAPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXX2-1", "uniprot_id": "S41A1_DANRE", "id": "E7EXX2-1", "name": "Solute carrier family 41 member 1", "aln": "----MVLWLKDQDKLSDMSTGTERI---------------------------------------EMKKEGVPPAYHHSNGSVHPVILPDSPEEVP-----------------------QTPGEYELTEVTSLPDCGDQENERPDMVVLDCRANAKGQREE-----------------------------DALLENASQSNESDD----------------------------------------TSTDQSPVP--------------PAPLKETSFSIGLQVLIPFLLAGFGTVAAGMVLDIVQHWTVFTEVTEVFILVPALLGLKGNLEMTLASRLSTAANIGQMDTAKDMWKMIMGNLALIQVQATVVGFLASIAAVIFGWIPEGNFRMGHAILLCASSVATAFIASLALGLIMIGVIIASRKVGINPDNVATPIAASLGDLITLSLLAGISTGLYKELEFNNYANPMVCAFFVALTPIWVLIARRIPSTREVLYSGWEPVIIAMAISSVGGLILDKTVSNPNFAGMAVFTPVINGVGGNLVAVQASRISTYLHMNALPIVEPNPAPRKCPTPWGTFFGSGVNSRSAKVLFLLVAPGHLVFLYTINSMRGGHTTLTYIFIAFYLAAALLQVIILLYLADWMVNWMWRRGMDPDNFSIPYLTALGDLLGTGFLALCFHILWLIGDRDTDVGD------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JV32-1", "uniprot_id": "A8JV32_DROME", "id": "A8JV32-1", "name": "SLC41A/MgtE integral membrane domain-containing protein", "aln": "MSCICEYSLERSQINAKMSLPNEQTNLPHNPSQPASADTQTPATATGTTTPSTPTPSTRTTQPNELKHRLTPLNVRRLSGYVNPQAISDNAGDDPPPTTINIGLFNNNNNNNTNNNNNNNNNNNNTASTTPPSAYATPPIYQQQLSTLTATTPLDVAPDDKYRLFTIFNGNDPDNEKLSGLPHSTTGSLSSIITTSIASSEPDPGAVSGGGGGGGGGGGGGGIGGAGGGGGGGGGNGGIGSGALVAADASSIAGINGSSEEKLALNRPGIKQEKWTTILLQVSIPFFLAGIGTIGAGIVLGRVEKWYVFKNVSELFILVPALLGLKGNLDMCLASRLSTQVNLGNMTSRQGVIRMIVGNIALVQVQATVASFLVAMFAVSVGAAMTGDFYFENMMLLTASAMFTATSSCFVLDFVLVAVILFSQKYRLNPDNLATPLAASIGDVVSISLLSFIASLLYDHIKTHLWITFIVVTCYLVLLPMWVMIVLRNEYTRPVLKSGWVPVLSALCISGLGGLVLDAAVE--VFNGFVVFQPIINGIGGNLVSVQASKISTMLHQSSIIGIIP-PHTQIFEWPWRALFKGVPYAKTARILIAMSIPGNVLFIFAADYINYSTSTVTWVFVLSYLTASLVQVMLLLYIAHIIVHAMWKWKIDPDNSAIPYLTALGDLLGSSLLAVAWLFTMSVGMQYGSGMETLNAPN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * * :: .* . * . .. .. : .: :: : . : . :: .::: .. *.*.* .::* . . *. :*. :* *** :**:***:**:.**:**. *::* ** :*:*:**************:* ******* .*:*:* : : : :** **:**:******..**.:: ** .* *.* : : :** **:: ** :.:.*.::::.**: *:* :****:***:***:**:::::**: *: ** .: : :* : ::.* *:**::. * ** ** *** **: *:.**.:***:** :*. * *:.** *:***:*****:****:*** ** ..: . .: * ::* :::*::*: : **:::*::: . :. . :*:* :*: *::*:*:**::***:*. :*: ** :**** :************:.:**:.: . :* : . : ", "identical_positions": 192, "similar_positions": 172, "identity": "27.47%" }, { "cls_id": "homologset.agr.MGI:2444824", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P1W8-1", "uniprot_id": "SIRPG_HUMAN", "id": "Q9P1W8-1", "name": "Signal-regulatory protein gamma", "aln": "MPVPASWPHPPGPFLLLTLLLGLTEVAGEEELQMIQPEKLLLVTVGKTATLHCTVTSLLPVGPVLWFRGVGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRISSITPADVGTYYCVKFRKGSPE-NVEFKSGPGTEMALGAKPSAPVVLGPAARTTPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPTGQSVAYSIRSTARVVLDPWDVRSQVICEVAHVTLQGDPLRGTANLSEAIRVPPTLEVTQQPMRVGNQVNVTCQVRKFYPQSLQLTWSENGNVCQRETASTLTENKDGTYNWTSWFLVNISDQRDDVVLTCQVKHDGQLAVSKRLALEVTVHQKDQSSDATPGPASSLTALLLIAVLLG----------PIYVPWKQKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A6YYP6-1", "uniprot_id": "A0A0A6YYP6_MOUSE", "id": "A0A0A6YYP6-1", "name": "Tyrosine-protein phosphatase non-receptor type substrate 1", "aln": "MLLLDAWTHIPHSVLLLILLLGFKGAAVR-ELKVIQPVKSFFVGAGGSATLNCTVTSLLPVGPIRWYRGVGQSRLLIYPFTGEHSPRITNVSDVTKRNNMDFSIRISNVTPADSGTYYCVKFQRGSSEPDIEIQSGGGTELLVLAKPSSPMVSGPAARAVPQQTVTFTCRSHGFFPRNLTLKWFKNGDEISHLETSVEPEETSVSYRVSSTVQVVLEPRDVRSQIICEVDHVTLDRAPLRGIAHISEFIQVPPTLEIRQQPTMVWNVINVTCQIQKFYPPSFQLTWLENGNISRREVPFTLIVNKDGTYNWISCLLVNISALEENMVVTCKVEHDEQAEVIETHTVLVTEHQRVKGTATKSELKTAGIAKIPVAVLLGSKILLLIAATVIYMHKKQNA", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :*.* * ..*** ****:. .* . **::*** * ::* .* :***:***********: *:**** .* *** . * **:*.***:*************.:**** ********::**.* ::*::** ***: : ****:*:* *****:.*::**:***.**** **::********:*:*.::*.*:* **:* : **.:***:* *****:**** ****: **** *::** *:******: *** * * :*****::**** *:**** ****:.:**.. ** ******** * :***** .:::*:**:*:** * * : :: ** **: :.: :.. :: * : :***** **: **::", "identical_positions": 219, "similar_positions": 96, "identity": "55.03%" }, { "cls_id": "homologset.agr.MGI:2444826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M8G3-1", "uniprot_id": "A0ABK0M8G3_RAT", "id": "A0ABK0M8G3-1", "name": "", "aln": "MTG-------SAADTHRCPHPKSIKG---TRSRSSHARPVSLATSGG---SEEEDKDGGVLFHVNKSGFPIDSHTWERMWLHVAKVHPRGGEMVGAIRNAAFLAKPSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGSYFHHVVLGIYCNGYYGSLGMSRRAELMDKPLTFRTLSDLVFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMRMKILKPASGHSPTQVRIRGKSLSPRRRQASPPRR---LGRRDKSPALTEKKVADLSTLNEVGYQIRI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C5G2-1", "uniprot_id": "VASH2_MOUSE", "id": "Q8C5G2-1", "name": "Tubulinyl-Tyr carboxypeptidase 2", "aln": "MTG-------SAADTHRCPHPKITKG---TRSRSSHARPVSLATSGG---SEEEDKDGGVLFHVNKSGFPIDSHTWERMWLHVAKVHPRGGEMVGAIRNAAFLAKPSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGYYGSLGMSRRAELMDKPLTFRTLSDLVFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMRMKILKPASAHSPTQVRSRGKSLSPRRRQASPPRR---LGRRDKSPALTEKKVADLGTLNEVGYQIRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86V25-1", "uniprot_id": "VASH2_HUMAN", "id": "Q86V25-1", "name": "Tubulinyl-Tyr carboxypeptidase 2", "aln": "MTG-------SAADTHRCPHPKGAKG---TRSRSSHARPVSLATSGG---SEEEDKDGGVLFHVNKSGFPIDSHTWERMWMHVAKVHPKGGEMVGAIRNAAFLAKPSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMRMKILKPASAHSPTQVRSRGKSLSPRRRQASPPRR---LGRREKSPALPEKKVADLSTLNEVGYQIRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B7N9-1", "uniprot_id": "A0A8M2B7N9_DANRE", "id": "A0A8M2B7N9-1", "name": "", "aln": "MTGPSATSSGSAAKISRHGRSKSTSAYCHSTGPAAESSPSTAANNTGRSSGEEEEKDGGVPFFVNRTGFPIESVTWERMWSHVAKVHPDGQEMVDRIRNATLLPKHSVPSVPNFKPSMSVPDWLHAVQNYMRNLQYNHTGTQFFEIKKTRPLSGLMETAREMIRESLPIKCLEAVILGIYLTNGLTSVERFPISFKTQFSGHHFHHVVLGVYCNGRYGTLGMSRRTDLMDRSLSFRTLSELVFDFEDSYRRYQHTMKKIKIGLYVPHNPHVFQPIEWNYLVINASKQAREDMRKELEKHGRDMRMKILKSSSAQSPIKERTRGKSLSPRRRPGSSPQRRQHAHRRDKSPAALDRKPAELSTLSD-GYQIRI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ***. * :.* .. : . ::.: * : *.. * .***:***** *.**::****:* ****** ******* * ***. ****::*.* *:*.***:: **::****:*:****:.*************:* **********:** ********************* .*:********* *** :*******:**** **:******::***:.*:*****:*:*******::* **:**:********:** ******: **:*.** * *:******:.*********.:*.:** : * ********** .*.*:* **:**** ::* *:*.**.: ******", "identical_positions": 239, "similar_positions": 74, "identity": "64.42%" }, { "cls_id": "homologset.agr.MGI:2444830", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N8D7-1", "uniprot_id": "NKAI3_HUMAN", "id": "Q8N8D7-1", "name": "Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3", "aln": "MG--CCTGRCSLICLCALQLVSALERQIFDFLGFQWAPILGNFLHIIVVILGLFGTIQYRPRYIMVYTVWTALWVTWNVFIICFYLEVGGLSKDTDLMTFNISVHRSWWREHGPGCVRRVLPPSAHGMMDDYTYVSVTGCIVDFQYLEVIHSAVQILLSLVGFVYACYVISISMEEEDTYSCD------------------------------LQVCKHLFIQMLQIIE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3URJ8-1", "uniprot_id": "NKAI3_MOUSE", "id": "Q3URJ8-1", "name": "Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3", "aln": "MG--CCTGRCSLVCLCALQLLSALERQIFDFLGFQWAPILGNFLHIIVVILGLFGTIQYRPRYIMVYTVWTALWVTWNVFIICFYLEVGGLSKDTDLMTFNISVHRSWWREHGPGCVRRVLPPSAHGMMDDYTYVSVTGCVVDFQYLEVIHSAVQILLSLVGFVYACYVISISMEEEDT-------------------------------------CRNK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LAP7-1", "uniprot_id": "A0ABK0LAP7_RAT", "id": "A0ABK0LAP7-1", "name": "Sodium/potassium-transporting ATPase subunit beta-1-interacting protein", "aln": "MG--CCTGRCSLVCLCALQLLSALERQIFDFLGFQWAPILGNFLHIIVVILGLFGTIQYRPRYIMVYTVWTALWVTWNVFIICFYLEVGGLSKDTDLMTFNISVHRSWWREHGPGCVRRVLPPSAHDMMDDYTYVSVTGCVVDFQYLEVIHSAVQILLSLVGFVYACYVISISMEEEDTFDFIG------------------------GLDAHSHYRDHVELKPVKPVEISNDIDSEMRLLDLS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6MHQ4-1", "uniprot_id": "NKAIN_DROME", "id": "A6MHQ4-1", "name": "Sodium/potassium-transporting ATPase subunit beta-1-interacting protein", "aln": "MGSCSCTRRHFLLSICFLQVITIIERQVFDFLGYMWAPILVNFFHILFIIFGFYGAYHFRVKYIITYLIWNFLWIGWNTFLICFYLNVGQLNRDSDLLNLGTG-SVSWFEANGYGCKP-TYNMAADDTFRPQRPERVEGCLLDYPLVEITHSGVQCALALLGILGAILISCIFLDEDDRFDFMNGDAKSPQHTVVHPMYVSYTSIPTTSASATMQSNKHLQLQHQQPQQNSLKLYHHQQQQQPKLHHFNKNYQLSGSNNNTLNNNLHQRAPALLPPNTTNNRSASFQTQSHPSNNHVTQRTGGEGSNCSSLRRHRQHHSKALVSPSPMSPQTTPSLSYASLQNSSPYLAGNSLSNSNYSIFQSPDSLQGSSHFARIHHKPKPPKSDYPVSGEFNPGGNISSPVRPLDRLSRSLEDDEDNFSLQKFAPGEHGVTYVPFQSPTPNSLFLGENNNSQPHLVFHTNSRSSPNNNAYPYDQSGLPSSLRMGSNSNARRPTHIPLPTVPMHNCQEVENDEDADGESEQDHDQMLTPPPPPLVRPHIHQRLGQAPYLDLSPEVAERYAIPSKLGPSLPIQVPLPVPHGSPMVRRSNRRPRPSNPVNFCDQIRATPPGYVVRAQSDDRLMEQVEADAAPHVNRRSGRGGSGQKTRPRSFCNSIVGVQG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .** * *:.:* **::: :***:*****: ***** **:**:.:*:*::*: ::* :**:.* :*. **: **.*:*****:** *.:*:**:.:. . **:. :* ** . :*.. : * **::*: :*: **.** *:*:*:: * : .* ::*:* : ", "identical_positions": 72, "similar_positions": 61, "identity": "10.91%" }, { "cls_id": "homologset.agr.MGI:2444831", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3ZCQ0-1", "uniprot_id": "RDD1_RAT", "id": "Q3ZCQ0-1", "name": "Required for drug-induced death protein 1", "aln": "MTVGARLRSKASS-LVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCER-EEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGN9-1", "uniprot_id": "RDD1_MOUSE", "id": "Q8BGN9-1", "name": "Required for drug-induced death protein 1", "aln": "MTVGARLRSKAASSLVGRRPLGRSRRAGDEETDAIVEHLEGEDEDPASPDCER-EEGGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNFGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7X2-1", "uniprot_id": "RDD1_HUMAN", "id": "Q9H7X2-1", "name": "Required for drug-induced death protein 1", "aln": "MTVGARLRSKAESSLLRRGPRGRGRTEGDEEAAAILEHLEYADEAEAAAESGTSAADERGPGTRGARRVHFALLPERYEPLEEPAPSEQPRKRYRRKLKKYGKNVGKVIIKGCRYVVIGLQGFAAAYSAPFAVATSVVSFVR", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********** * *: * * ** * ****: **:**** ** : :. . * .** .*****:* *****:.******.::*:*************.**.* *****:***************.**********", "identical_positions": 97, "similar_positions": 20, "identity": "68.31%" }, { "cls_id": "homologset.agr.MGI:2444835", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGC4-1", "uniprot_id": "PTGR3_MOUSE", "id": "Q8BGC4-1", "name": "Prostaglandin reductase-3", "aln": "MLRLAAAGARAIVDMSYARHFLDFQGSAIPRTMQKLVVTRLSPNFHEAVTLRRDCPVPLPGDGDLLVRNRFVGINASDINYSAGRYDPSLKPPFDIGFEGIGEVVALGLSASARYTVGQAVAYMAPGSFAEYTVVPAS-IAIPMPS-VKPEYLTMLVSGTTAYLSLEELG----ELSEGKKVLVTAAAGGTGQFAVQLSKIAKCHVIGTCSSDEKAAFLKSIGCDRPINY-RTEPVETVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQSPTGLSPIKAGVLPTKLLKKSASLRGFFLNHYFSKYQAAMERLLELYARGDLVCEVDLGHLAPDGRFIGLESVFQAVDYMYTGKNTGKLVVELPHPVSSKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A264-1", "uniprot_id": "D4A264_RAT", "id": "D4A264-1", "name": "15-oxoprostaglandin 13-reductase", "aln": "MLRLATAGARAIVDMSYARHFLDFQGSAIPRTMQKLVVTRLSPNFHEAVTLRRDCPVPLPGDGDLLVRNRFVGINASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSASAKYTVGQAVAYVTPGSFAEYTVVPAS-IAIPMPS-VKPEYLTLLVSGTTAYISLKELG----ELSEGKKVLVTAAAGGTGQFAVQLSKLAKCHVVGTCSSDEKSAFLKSVGCDRPINY-RTEPVETVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQSPTGLSPVKAGALPAKLLKKSASLRGFFLNHYFDKYQAAMEHLLQLYTRGDLVCEVDLGHLAPEGRFIGLESIFQAVDYMYSGKNIGKLVVELPHPVSSKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N4Q0-1", "uniprot_id": "PTGR3_HUMAN", "id": "Q8N4Q0-1", "name": "Prostaglandin reductase 3", "aln": "MLRLVPTGARAIVDMSYARHFLDFQGSAIPQAMQKLVVTRLSPNFREAVTLSRDCPVPLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSASARYTVGQAVAYMAPGSFAEYTVVPAS-IATPVPS-VKPEYLTLLVSGTTAYISLKELG----GLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRPINY-KTEPVGTVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQTPTGLSPVKAGTLPAKLLKKSASVQGFFLNHYLSKYQAAMSHLLEMCVSGDLVCEVDLGDLSPEGRFTGLESIFRAVNYMYMGKNTGKIVVELPHSVNSKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P38230-1", "uniprot_id": "QOR_YEAST", "id": "P38230-1", "name": "Zeta-crystallin", "aln": "------------------------MKCTIPEQQKVILIDEIGG---YDVIKYEDYPVPSISEEELLIKNKYTGVNYIESYFRKGIYP--CEKPYVLGREASGTVVAKGKGVTN-FEVGDQVAYISNSTFAQYSKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLFAAAGGVGLILNQLLKMKGAHTIAVASTDEKLKIAKEYGAEYLINASKEDILRQVLKFTNGKGVDASFDSVGKDTFEISLAALKRKGVFVSFGNASGLIPPFSITRLS----PKNITLVRPQLYGYIADP--EEWKYYSDEFFGLVNSKKLNIKIYKTYP--------LRDYRTAAADIESRKTVGKLVLEIPQ------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:**. : ::: .:. * .* *** .: :**::*::.*:* : : * * : *: :* *. * *** * ..: : **: ***:: .:**:*: :.:. . :*. .. * *.: .:* :: .: :.:*. **: *****.* : ** * .*.:...*:*** : *. *.: ** : : : *** :***. ::*** *:::: ** ** :: :* ** .* .:: :. * :: ..: *:: : .::: ..:: : .* :: *.. *. : *. **:*:*:*: ", "identical_positions": 84, "similar_positions": 121, "identity": "21.88%" }, { "cls_id": "homologset.agr.MGI:2444846", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IP70-1", "uniprot_id": "Q8IP70_DROME", "id": "Q8IP70-1", "name": "", "aln": "-----------------MAMAGPHRLPRPHTRRRFRLQAEFNVRQLAITIIATAAVTMLMTATPTLAEIPSKG---------------------------------------------KHTRLDTQQTAQEDSDFPRFAEPIANVTVSVGRDALMACVVENLKGY-----------KVAWVRVDTQTILSIH-HNVISQNSRISLTYNDHR---SWYLHIKEVEETDRGWYMCQVNTDP-MRSRKGYLQVVVPP-IIVEGL-TSNDMVVREGQNISLVCKARGYPEPYVMWRREDGE-----EMLIGG-EHVNVVDGELLHITKVSRLHMAAYLCVASNGVPPSISKRVHLRVQFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYWTTER--------------------GDMIISDTSRAGDKYETTSTVSG--YTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTPTT--------AIISEMSLLNRSYDGKRRHRNKFDSANALPDYGVEEWRDGAQGNNAGNNG----DNNQTPVRNPPGAFHNSAGSLAQHNLLAKIMLGIKTQSFGIFKRLSSSLPLAAGQSFLWLSTLSLVSAPSRWRMSNVENRPNSPETVVNNDTAAECWETRSHCVSESNNNNNSRITQRPPMWARHLRIFHIAHTPCGASTQYQRLCERQWQWQRLWQWQCQWKWQHQWQWPMLICIVILAGCFVRWLPMLLHFIGRHIGTFSISATHRQHLMCTFWDNRGNKVVAKNTTPARPSTFEMLCSRMFSR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8JNC7-1", "uniprot_id": "A8JNC7_DROME", "id": "A8JNC7-1", "name": "", "aln": "-----------------MFILTVVKLLLIALN---IFPSRFTNRRIMFLIYMTNLVTHVMMDE------------------------------------------------------------------------PRFAQPIPNVTVAVGRDANLPCVVEHLGGY-----------KVAWIHIDRQMILTIH-RHVISRIPRYSITYTDN----TWLLHVNQAHQDDRGYYMCQVNTNP-MISQVGYLQVVVPPNILDIES-TPSSVAVRENQNINMTCRADGFPAPKIIWRREDGE-----EIAVEKKKKVLVYDADVLPLTKVSRNEMGAYLCIATNGVPPSVSKRIILDVEFSPMIWVPNQLVGAPSGTDVTIDCHTEAHPKAIIYWVYN---------------------SVMVLPSK-----KYKTDYTENS--YRAHMKLTIRNLQYGDFGNYRCISKNSLGETEGSIRVYEIPLPST--------PSKQVTHTTVESRENNIIPSSRNDTTKSLQT-------------DVGYAM----KNDLYPG--------------------------------------SASSSSSGGSS-------SAASSSSSMQTSALPGG-------VAGNSLSSMGSKGSLAIGKS-----TFYTERPP-------------NEYAASSVAGLLLHRALLFG--------------------------SGIYLTLL-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMN9-1", "uniprot_id": "Q9VMN9_DROME", "id": "Q9VMN9-1", "name": "", "aln": "---------------MQSNFCQCRKQ--------------------------TCALSVILLLILMSQQCYPQR---------------------------------------------VEVPAEVIVD-------PKFSSPIVNMTAPVGRDAFLTCVVQDLGPY-----------KVAWLRVDTQTILTIQ-NHVITKNQRIGIANSEHK---TWTMRIKDIKESDKGWYMCQINTDP-MKSQMGYLDVVVPPDILDYP--TSTDMVVREGSNVTLKCAATGSPEPTITWRRESGV-----PIELATGEEVMSIEGTDLVIPNVRRHHMGAYLCIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINYWTRER--------------------GEIVPPGG-----KYSANVTEIGG-YRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKLYRIPPN------------------AVNYVENFEARHKGKKRTKSSES------------HHPARAQ----EHSGEDM--------------------------------------ENPGKRKADLS--------LGAES--------IDSIYGNSAAGSRRR-----------------------QDLGG-------------VLLLLLPVAVAVAMSLATAG------------------------VMRETQMTLPPQT----LTHV------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMN6-1", "uniprot_id": "Q9VMN6_DROME", "id": "Q9VMN6-1", "name": "", "aln": "------MKIKIFPLTADAATIAARRQRRRAAGKLQRKREMPEISSRLIVATATAAVVSIICLSLALPGCAAQESDDEGELHHLDQMHHQHQDFIIGESEEHDHIAHHLAEMQNKDELLEDIREDTVVNAIPEKDLPKFGELLQNVTVPVSREAVLQCVVDNLQTY-----------KIAWLRVDTQTILTIQ-NHVITKNHRMSITHAEKR---AWILRIRDVKESDKGWYMCQINTDP-MKSQVGYLDVVVPPDILDYP--TSTDMVIREGSNVTLKCAATGSPTPTITWRREGGE-----LIPLPNGAEAVAYNGSFLTIAKVNRLNMGAYLCIASNGIPPTVSKRVMLIVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINYWMKN---------------------DTIIVPGE-----RFVPETFESG--YKITMRLTIYEVDIQDFGAYRCVAKNSLGDTDGAIKLYHIPQTTT--------MTTMAPTVSINTVPVVLVKYNKEQRYGSSQNSNTNPY-----NFNPGNSQ----QNTKLQR--------------------------------------GKSNSKGSDQSPSGLNNVFVGATSSLWNSQDHHSSSSSSSSASSRGRDHHQQQHHQQQQQNHGSDHGASYRSDGK-------------SPHLTNHDAKSLTDDLDRMQ------------------------DLKGWASRLSPISPILGLSMILGVGYLGPWPG-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLF0-1", "uniprot_id": "Q9VLF0_DROME", "id": "Q9VLF0-1", "name": "", "aln": "MLPPSWHLIGALLVLAATAGDSTNKIILPQILNGGGGGGGVGTAQGKHPSGSKTVATGVVPNFGGAAGNGAGGGGPVAGSG-----------------------TGSTVVGSNGVIVAGGGANVPTSNLNIVVEEPEFTEYIENVTVPAGRNVKLGCSVKNLGSY-----------KVAWMHFEQSAILTVH-NHVITRNPRISVTHDKHDRHRTWYLHINNVHEEDRGRYMCQINTVT-AKTQFGYLNVVVPP-NIDDSL-SSSDVIVREGANISLRCRASGSPRPIIKWKRDDNS-----RIAINKNHIVNEWEGDTLEITRISRLDMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGE--------------------GPIIHDSH-----KYKVEATVGLPAYKTHMKLTIINVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPPTT--------ASSGIYSTDTHWGENGINNNYAYGGPDSTRS--------------IYAQD----KNTRYQSN-------------------------------------LNEIGLSEQKS-------FLDKTQNPLLANGNANEADAESNGARGHN-----------------------------------------PSMAIAWLFVVIATLLLTIR------------------------SAVGSSHSLSLC---------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VAR6-1", "uniprot_id": "Q9VAR6_DROME", "id": "Q9VAR6-1", "name": "", "aln": "----------------------------------------------MEKLLQSTLFVILIMATKCGSGS---------------------------------------------------TQNQHHESSSQLDPDPEFIGFINNVTYPAGREAILACSVRNLGKN-----------KVGWLRASDQTVLALQ-GRVVTHNARISVMHQDMH---TWKLKISKLRESDRGCYMCQINTSP-MKKQVGCIDVQVPPDIINEE--SSADLAVQEGEDATLTCKATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDVPPAVSKRVSLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASPSPVSYWLKGARTSNGFASVSTASLESGSPGPEMLLDGP------KYGITER-RDGYRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEIKL-------------HPGASASNDDHLNYIG---------GLEEA------------ARNA-----------------------------------------------------------GR-SNRTTWQPLLAMLMLLWMR-------LSLRTGGA------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7Z153-1", "uniprot_id": "B7Z153_DROME", "id": "B7Z153-1", "name": "", "aln": "-------MMNLLVVKESGERIADISCSQEHTTKFSPKLSQVAKHRKLAQLEIASGSGLVGLGTGTGTGSGCGPAIRWQLLL-------------------------------LLLLGNCIDLTVSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIH-EHVITNNDRLSVQHNDYN---TWTLNIRGVKMEDAGKYMCQVNTDP-MKMQTATLEVVIPPDIINEE--TSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARN-GSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQR----------------ENG----EMIIAGD------RYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRLYEME--------------RPGKKILRDDDLNEVSKNEVVQKDTRSEDG------------SRNLNGRLYKDRAPD-------------------------------------QHPASGSDQLLGRGTMRLIGTFLLALLVLFTALAEAGPTTLSCRTKGGRQKKAKETSWNGRRARDGRED----GHAAEWRQCWERSALSWRRSAPPELDYYSLIQL--------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4R3-1", "uniprot_id": "Q9W4R3_DROME", "id": "Q9W4R3-1", "name": "", "aln": "--------------------------------------MPVSAKRLLRNFQFTSCDRNGKMLIHL--------------------------------------------------------LLIVSLLEAIGAFQPEFVESISNVSVAVGRDATFTCHVRHLGGY-----------RVGWLKADTKAIQAIH-ENVITHNPRVTVSHLDQN---TWNLHIKAVSEEDRGGYMCQLNTDP-MKSQIGFLDVVIPPDFISED--TSSDVIVPEGSSVRLTCRARGYPEPIVTWRREDGNEIVLKD-NVGTKTLAPSFRGEVLKLSKISRNEMGSYLCIASNGVPPSVSKRISLSIHFHPVIQVPNQLVGAPLGTDVQIECHVEASPKSINYWIK----------------DTG----EMIVTSG------KYHVQESSQSMYETKMSMIVRKFQKDDVGSYRCIAKNSLGEVDSSIRLYEIPGPNRNKNPLNGGGKGGGAGGSLDADANDILKQKQQVKVTYQPEDEELQYGSVEDFEAEGGEGGGLTPLSPH-------------------------------------VYYTSGNKPATHKPGNSGGNQHLHQQHHHHHHHNNNNNNQQHSGGPGGGPTGGDAGSLGGEMGGITRKPPPYYGGNTEVRGPIDNNEMSSGSGDSRLCRGHHLPILLLPFAR----------------------LILVRSWHCRHTFLMGLSQACLPGLLLSLL----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7PLL7-1", "uniprot_id": "Q7PLL7_DROME", "id": "Q7PLL7-1", "name": "", "aln": "------------------------------------MLTKKTARIKMYNGTLACSIAFILIKAITITKCH--------------------------------------------------AVAHIHGKGESEEIDPQFLAKLSNTTVPIGRDISFTCVVDNLGHY-----------RVAWIKSDSKAILGIH-THMVSLNPRLSVTHNGHN---TWKLHISRVQINDSGSYMCQVNTDP-MKSLSGYLDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRPKVLWRREAGK-EIILRTDGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPPSVSKRFNVYVNFSPTVKAISQLVGAPVEREVTLECIVEVFPKPLNGWYRSE--------------------GNIKLHNG-----NKYNISEEVINIYTWHLNLTIRHLTKSDFGTYSCSSVNALGKSESLIRLQELRLPPK---------LTTTPTPHMQTTGKSRRKHPASHKKGLNEVLR---------FQETHFANQIQQENEDHNEG-----------------------------------FDLLKFTNSENSNIVLESGHINSMINKEDVNIYHPKQYGQEKTNKPSGTIPSTRTPWILTNAGSQRPALTSYATVALITSFWLFFWRVFHSLDWDAIRVSSVVHHVVVFKR-------------------------RSYFEAPNYALRITVLQMLQELRTLVIEQ--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9Z0J8-1", "uniprot_id": "NEGR1_RAT", "id": "Q9Z0J8-1", "name": "Neuronal growth regulator 1", "aln": "---------------------------------------------MVLLAQGACCSNQWLAAVLLSLC----------------------------------------------------------SCLPAGQSVDFPWAAVDNMLVRKGDTAVLRCYLEDGASKG------------AWLN--RSSIIFAG-GDKWSVDPRVSIST--LNKR-DYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDIS----NDMTINEGTNVTLTCLATGKPEPAISWRHISPS-------------AKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVVVNFAPTIQEIKSGTVTP-GRSGLIRCEGAGVPPPAFEWYKGE---------------------KRLFNGQ----------QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNP---PST-------------------------AQYGITGSACDLFS------------------------------------------------------------------------------------CWSLALTLSSVISIFYLKNAILQ------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80Z24-1", "uniprot_id": "NEGR1_MOUSE", "id": "Q80Z24-1", "name": "Neuronal growth regulator 1", "aln": "---------------------------------------------MVLLAQGACCSNQWLAAVLLSLC----------------------------------------------------------SCLPAGQSVDFPWAAVDNMLVRKGDTAVLRCYLEDGASKG------------AWLN--RSSIIFAG-GDKWSVDPRVSIST--LNKR-DYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDIS----NDMTINEGTNVTLTCLATGKPEPVISWRHISPS-------------AKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVIVNFAPTIQEIKSGTVTP-GRSGLIRCEGAGVPPPAFEWYKGE---------------------KRLFNGQ----------QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNP---PST-------------------------AQYGITGSACDLFS------------------------------------------------------------------------------------CWSLALTLSSVISIFYLKNAILQ------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3B1-1", "uniprot_id": "NEGR1_HUMAN", "id": "Q7Z3B1-1", "name": "Neuronal growth regulator 1", "aln": "-------------------------------------------MDMMLLVQGACCSNQWLAAVLLSLCC------------------------------------------------------LLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKG------------AWLN--RSSIIFAG-GDKWSVDPRVSIST--LNKR-DYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDIS----NDMTVNEGTNVTLTCLATGKPEPSISWRHISPS-------------AKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTP-GRSGLIRCEGAGVPPPAFEWYKGE---------------------KKLFNGQ----------QGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNP---PST-------------------------AQYGITGSADVLFS------------------------------------------------------------------------------------CWYLVLTLSSFTSIFYLKNAILQ------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B3I9-1", "uniprot_id": "A0A8M3B3I9_DANRE", "id": "A0A8M3B3I9-1", "name": "Neuronal growth regulator 1", "aln": "-------------------------------------------MDIMIAVQDACVSGQWLTAIILSLCC------------------------------------------------------FLPSCLPAGQTVDYTTSSES-VVSRQGDTALLRCYLLDGISKG------------AWLN--RSSIIYAG-NDKWSGDPRVSIVSNVGDKH-EYSLQIQKVDVTDEGVYTCSIQSERNLHPKLIQLIVKVPPKIYDIS----SDITVNEGSNVSLICAASGKPEPKISWRHISPS-------------ARKYESGEYLNITGISRDQAGDYECGAENDIASPDTKTVRVTVNFPPAIHEMKSHGVRP-GQVALLRCEAAAVPSPVFEWYKGE---------------------KRINMG-----------QGIVINNLSSRSVLTVKNMTQDRYGNYTCVAVNRLGTANASVPLNPIIEPTTT--------------SAVSSPASNPAMYGSTGGAEVLLA------------------------------------------------------------------------------------CWYLILALSSLVTVY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24372-1", "uniprot_id": "LACH_DROME", "id": "Q24372-1", "name": "Lachesin", "aln": "---------------------------------------------MWRPSISNCVWSTLLLAIFVQQT--------------------------------------------------------------LAQRTPTISYITQEQIKDIGGTVEFDCSVQYAKEYN-----------VLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSS--TYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDN--STQSVVASEGSEVQMECYASGYPTPTITWRRENNAILP---------TDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAPVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDD----------------------IQLANN-----QHYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETIIPVCP---------------PACGQAYIAGAEDVSATS------------------------------------------------------------------------------------------FALVGILAALLFAR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : ::. . : * : : :.: * * * *.: * . *. . : * . * * * : *:: . * : : : . . * * * *.:. : . : :.* * : : * * . * . : : . * * * : * * :. : : ", "identical_positions": 28, "similar_positions": 49, "identity": "3.54%" }, { "cls_id": "homologset.agr.MGI:2444847", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6DFV7-1", "uniprot_id": "NCOA7_MOUSE", "id": "Q6DFV7-1", "name": "Nuclear receptor coactivator 7", "aln": "---------------------------------------------------------------MDTKEEKKEQKERKQSYFARLKKKKQAKQNAEIVSAASSKSRSGKDDANSDILEQDK-----------------------------FNVTAEGDHSTDDKKKRKSNQLKEIRRTELKRYYSVD----------------------------------------------------------------------------------------------------------------------DNQNKTHDKKEKKMMVQKPQGTMEYTAGSQDTLNSVALKFNVTPNKLVELNKLFTHTIVPGQVLFVPDANISSSTIQLSSSTPGATVSPSSSDAEYDKLPDADLARKALKP-----------IERVLSSTSE----------EDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYSDISHMKIKDALPS------------------------------------------DLPRDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQ---------------------------------QNGERTLALDAKSVRSPEESTERTCTRIEPPDNSELWKLKNLQSSRGTTSESPSVTQLS-----MRAALEPTAKENCLLKGDEDFVDLEELSSQ--PESGINKGDATKECLSYD---QKKDG----------PHTVMSAKKGHVQSAQEVMGPESDTELKGALDLETAEKQDEAPEVDKHSGSPENLGESTLNIHEDLDK----IKLIEFYLNKNKEGSQLLENVQKSELSDRKSIEPGGIDITLSSSLPQAGDSPPEDNKEPGTLWVKGGETLPLKLDP--------------------------SAEETVINNKEVLDS-LGSSLDKMCHSAQMDNKSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHTATMVQQYSKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKE----QGFVVVEKEELNMIDN--------------FFSEPTTKSWEIITVEEAK-----------------------------RRKSTCSYYEEEEEEEEGLPILQPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKK-EDFIVQDLEVWTFE-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LWN1-1", "uniprot_id": "F1LWN1_RAT", "id": "F1LWN1-1", "name": "", "aln": "---------------------------------------------------------------MDTKEEKKEPKERKQSYFARLKKKKQAKQNAEIVSAARSHS--GKDDSHSVILEQDK-----------------------------SNIAAEGDQSTDEKKKRKNNQLKEIRRMELKRYYNAD----------------------------------------------------------------------------------------------------------------------DNQSKSHDKKEKKMVVQKPQGTLEYTAGSQDTLNSVALKFNVTPNRLVELNKLFTHTIVPGQVLFVPDANIPSSTLRLSSSTPGATVSPSSSDAEYDKLPDADLARKALKP-----------IERVLSSTSE----------EDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPS------------------------------------------DLPRDVCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQ---------------------------------QNGERTLALDVKSVGSPEESTERMRTRTEPPDDSESWKLKNLEYSRGTASEFPSVTQLSKGPSSVCAALEPTAKENRLL-GDEDFVDLEELSSQ--PGSGMDKGDARKECLPYD---QKKDA----------PQTIMSAKKGEEQSAPDVTGTESDAELKGALDSETGEKQDEAPEVDKQSGSPENWRESTLSIHEDLDK----VKLIEFYLNKNKEGSQLSENVLKSELSERKSIEPDGIDITLSSSLPQAGDSPPESHKEPGTLCVKGGGTPPPKLHP--------------------------SAEETVTNNKEALDS-LESSLDKLCQGAQMDNRSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHSTTMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKE----QGFVVVEKEELTMIDN--------------FFSEPTTKSWEIITVEEAK-----------------------------RRKSTCSYYEEEEEEEEGLPILQSHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFRFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKK-EDFIVQDLESIITAQTDPGRLPVEDRHRRQKSEVQIV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NI08-1", "uniprot_id": "NCOA7_HUMAN", "id": "Q8NI08-1", "name": "Nuclear receptor coactivator 7", "aln": "---------------------------------------------------------------MDTKEEKK---ERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDK-----------------------------CNIAVEEEYMTDEKKKRKSNQLKEIRRTELKRYYSID----------------------------------------------------------------------------------------------------------------------DNQNKTHDKKEKKMVVQKPHGTMEYTAGNQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSPSSSDAEYDKLPDADLARKALKP-----------IERVLSSTSE----------EDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPS------------------------------------------DLPQDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQ---------------------------------QNGEKIMTSDSRPIVPLEKSTG--HTPTKPSGSSVSEKLKKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLG-EDDDFVDLEELSSQ--TGGGMHKKDTLKECLSLDPEERKKAE----------SQINNSAVEMQVQSALAFLGTENDVELKGALDLETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDK----VKLIEYYLTKNKEGPQVSENLQKTELSDGKSIEPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNS--------------------------STEANVI--KEALDSSLESTLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKE----QGFVVVEKEELNMIDN--------------FFSEPTTKSWEIITVEEAK-----------------------------RRKSTCSYYEDEDE--EVLPVLRPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKK-EDFIVQDLEVWAFD-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0B4K620-1", "uniprot_id": "A0A0B4K620_DROME", "id": "A0A0B4K620-1", "name": "Oxidation resistance protein 1", "aln": "MSIIDSGKYRLRKDWASASIPSLVNIDEHDGDSGDTEGSLNATAPLPPQKPPRRSSLALGLFSSKSDKSQKRRSSIAVSFLRRDSSKNSTKDSYESAVRSEKSDGSGTPTSPEIVYSSEENIRASSPNDPGKQTFFEDGSQSPRPVLQGLNTSYEGPQNDRQRRRRSSLQTKLDRHRRKKMEYSNQRSLDSGMMCSESHSDLTNDSLAEGSGSFANRSRNGNDDEDDIIDPSHGEYFPREKRHSWWNIFVPDNFKNRSRRASQDVSSLSRSVDNLAIPVRRSKSRSVDHGLAAPFDLDSLRSKVEQRFESVDKLSRQKSSLPTIPTISYTVGNRDTLTSVAARFDTTPSELTHLNRLNSSFIYPGQQLLVPDKSAKDDASSSSTHDADGASLSGKSSPVERKLSGDESREKDILEGLRPGSPKPGHIERVGGSSQQQQAEEEANKSDDPVITQRFLKINVRHITDGQGVVGGVLLVTPNAVMFDPNVSDPLVIEHGPESYGVIAPMELVVNAAIFHDIAHMRVAGGAGQGLNSASGDAEKPEIYYPKPVLVEEDSKELPEQQSLLGEDGNKRLDAEIGSLEIADDQESLCSSTGRDGDAFPKAFDRERVEDSSMEAKDSAKTDALDDEDKKAGLGLSSTRSTLEERRKSLLDHHWAIPSKDRSSEDEGDNESNVTVDSGARVQDPHSANSSVSGVP-LSQPPVAAAAAAAAVAPASAVVPLPPSGIDLEHLEQLSKQSCYDSGIDIREPVPNVQPIPKKTVYSDADIVLSSDWVPPKTIVPTHFSESPPRSTILGQSLDAGTGGAGGVRKKTSSVSFSVDDEAAQQAQAQSAALAVTDKQADKKNKMLKRLSYPLTWVEGLTGEGGAVPPGGVGSGSLNKSGDTDSAPNTGDSNQSVFSKVFSSSPITLVSELGGNLFSKTPSEDSGGSPVPPLTPHSTHSEGHMTYGRSSIGTFIRPHSSEGTSSSTKLKEAKQAPKLDYRSMVSMDDKPELFISVDKLIPRPARACLDPPLYLRLRMGKPIGKAIP--LPTSVMSYGKNKLRAEYWFSVPKNRVDELYRFINTWVKHLYGELDEEQIKARGFELIQEDTEWTKSGTTKAGMGGGSQDGEEISDLTRESWELIKAPFAKTYKIIKTASHAASHDLEMLGGEVLSMSTDEYRKTSLFATGSFDLDFPIPDLIGKTEILTEEHREKLCSHLPARAEGYSWSLIFSTSQHGFALNSLYRKMARLESPVLIVIEDTEHNVFGALTSCSLHVSDHFYGTGESLLYKFNPSFKVFHWTGENMYFIKGNMESLSIGAGDGRFGLWLDGDLNQGRSQQCSTYGNEPLAPQ-EDFVIKTLECWAFV-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08952-1", "uniprot_id": "OXR1_YEAST", "id": "Q08952-1", "name": "Oxidation resistance protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFGVKDAIFKIKRSIAGTDSSDSTAYTTASESSPQLKDSHNPFRNKTTSERTIVEEGSLPPVRLNG----------------------------------------------------------------------------YLPSTKNKLLTPEMCDEIRT----------LMPTRIQLYTEWN--LLYSLEQHGSSLHSLYSNVAPDSKEFR---------RVGYVLVIKDRKNGIFG----------------------------------------------------------------------------------------AYSNEAFHPNEHRQYTGNGECFLWKLDKVPDVN--------------------ISEKEESEQEGKEGKEEGDKEERWR-------------FSGYPYTGVNEFAIYCTSEFLSMGAGDGHYGLLCDDGLLHGVSNPCQTYGNEVLSKEGKKFSIVALEVWRVG-----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .. : .: : . . . : * : :* . * : :: .: : * : . * : . :. ** . .. *: :: :: . : . : : ... : : * * . : : :. : : * . .::: *. : ::* * : * . *.:*.*.*::** * .* :* *: *.*:.*: *: : :.* : ** ", "identical_positions": 32, "similar_positions": 82, "identity": "2.33%" }, { "cls_id": "homologset.agr.MGI:2444848", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZZ93-1", "uniprot_id": "A0A8I5ZZ93_RAT", "id": "A0A8I5ZZ93-1", "name": "Peptidyl-tRNA hydrolase 2, mitochondrial", "aln": "--MLSKL-------LTMEYLVHPGTLSLAAGVACG----------MCLGWGLRSHLGIFPQNSTSETNRDTEMGTEASILGE-----SGEYKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQIQRRN------PQVLKEWEYCGQPKVVVKAPDEDSLIQLLTHAKALGLTVSLIQDAGRTQIEPGSRTVLGIGPGPVELIDEVTGHLKLY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2Y8-1", "uniprot_id": "PTH2_MOUSE", "id": "Q8R2Y8-1", "name": "Peptidyl-tRNA hydrolase 2, mitochondrial", "aln": "--MLSKF-------LTMEYLVHPGTLSLAAGVACG----------MCLGWGLRSHLGMFPQNSTSEANRDTETGTEASILGE-----SGEYKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQTQRRS------PQVLKEWEYCGQPKVVVKAPDEDTLIQLLTHAKTLGLTVSLIQDAGRTQIEPGSRTVLGIGPGPVELIDEVTGHLKLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3E5-1", "uniprot_id": "PTH2_HUMAN", "id": "Q9Y3E5-1", "name": "Peptidyl-tRNA hydrolase 2, mitochondrial", "aln": "--MPSKS-------LVMEYLAHPSTLGLAVGVACG----------MCLGWSLRVCFGMLPKSKTSKTHTDTES--EASILGD-----SGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRN------PEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GKN0-1", "uniprot_id": "A0AC58GKN0_DANRE", "id": "A0AC58GKN0-1", "name": "Peptidyl-tRNA hydrolase 2, mitochondrial", "aln": "MTLLAKQSSLRMRDMRLDSLYGPVGLGVLAGLGCG----------LCVGWHLSGRFGRSSRSMMTALGNSASNGSETSVMGE-----SGEFKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQVQRRN------PELLKQWEYSGQPKVVVKAPDEDCLLDLLAHAKEVGLPVSLIQDAGRTQIAPGSRTVLGIGPGQADLIDKVTGHLKLY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O97067-1", "uniprot_id": "PTH2_DROME", "id": "O97067-1", "name": "Probable peptidyl-tRNA hydrolase 2", "aln": "--MGDKL-------LDPTQIINGLAVMLSFFVGYR----------YALKRGDAKDSVTEGAATPFSQESSVSSGSEASVSDKGYGGLNDNFKMVLVVRNDLKMGKGKIAAQCGHGAVGAYQRAVVRT------PRLLRSWENCGCAKIAVRVESEAELMAIKKEAERQQLNTCLIRDAGRTQIEANSKTVLAVGPAAAADIDRVTGHLKLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG06-1", "uniprot_id": "Q9VG06_DROME", "id": "Q9VG06-1", "name": "peptidyl-tRNA hydrolase", "aln": "--------------------MPTSSSILQKFLSNG----------LAFG---------------------------------------KSTKLALVVRTDLKMSKGKTAAQCAHAAVMCYQSSVQGTK---LQNAILQRWCRLGQPKIVLRVDNFEQLNSLERQAQESNVVAALVRDAGRTQLESGTATVLGLGPAPAEDLDKLVAHLKLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34222-1", "uniprot_id": "PTH2_YEAST", "id": "P34222-1", "name": "Peptidyl-tRNA hydrolase 2", "aln": "---MEKMTVSSNYTIALWATFTAISFAVGYQLGTSNASSTKKSSATLLRSKEMKEGKLHNDTDEEESESEDESDEDEDIESTSLNDIPGEVRMALVIRQDLGMTKGKIAAQCCHAALSCFRHIATNPARASYNPIMTQRWLNAGQAKITLKCPDKFTMDELYAKAISLGVNAAVIHDAGRTQIAAGSATVLGLGPAPKAVLDQITGDLKLY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. . . :: **:* ** * *** **** *.*: .:: : : * * .*:.:: . : : .* : ..:::******: ..: ***.:**. :*.:...*** ", "identical_positions": 34, "similar_positions": 43, "identity": "16.11%" }, { "cls_id": "homologset.agr.MGI:2444851", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZM57-1", "uniprot_id": "A0A8I5ZM57_RAT", "id": "A0A8I5ZM57-1", "name": "Protein EFR3 homolog B", "aln": "-------------------------------------------------------MYGVCGCCGALRPRYKRLVDNIFPE--DPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHRYGYVCIAMEALDQLLMACHCQS-INLFVESFLKMVAKLLESEKPN----LQILGTNSFVKFANIEEDTPS---------YHRSYDFFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQH------VEEAESRSPSPLQAPEKEKENPAELAERCLRELLGRAAFGNIKNAIKPVLIHLDNHSLWEPKVFATRCFKIIMYSIQPQHSHLVIQQLLSHLDANSRSAATVRAGIVEVLSEAAVIAATGSVGPTVLEMFNTLLRQLRLSIDYALTGSYDGAVSLGTKIIKEHEERMFQEAVIKTIGSFASTLPTYQRSEVILFIMSKVPLPSLHHPVETGRTGENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTALMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLGDISVLKLKVDKCSRQDTVFMKKHSQQLYRHIYLSCKEETNIQKHYEALYGLLALISIELANEEVVVDLIRLVLAVQDVAQVNEENLPAYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAPYMLPEDVFVEKPRLA-QNLDGVVIEFLFRQSKISEVLGGSGYNADRLCL--PYIPQLTDE------------DRLSKRKSIGETISLQVEVESRNS-PEKEERVPAEEITYETLKKAIVDSVAVEEQE--RERRRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIFEITIRPPPSPSGTISAAYGQPQNHSIPVYEMKFPDLCVY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQ18-1", "uniprot_id": "EFR3B_MOUSE", "id": "Q6ZQ18-1", "name": "Protein EFR3 homolog B", "aln": "-------------------------------------------------------MYGVCGCCGALRPRYKRLVDNIFPE--DPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHRYGYVCIAMEALDQLLMACHCQS-INLFVESFLKMVAKLLESEKPN----LQILGTNSFVKFANIEEDTPS---------YHRSYDFFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQH------VEEAESRSPSPLQAPEKEKENPAELAERCLRELLGRAAFGNIKNAIKPVLIHLDNHSLWEPKVFATRCFKIIMYSIQPQHSHLVIQQLLSHLDANSRSAATVRAGIVEVLSEAAIIAATGSVGPTVLEMFNTLLRQLRLSIDYALTGSYDGAVSLGSKIIKEHEECMFQEAVIKTIGSFASTLPTYQRSEVILFIMSKVPLPSVHHPVETGRTGENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTALMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLGDISVLKLKVDKCSRQDTVFMKKHSQQLYRHIYLSCKEETNIQKHYEALYGLLALISIELANEEVVVDLIRLVLAVQDVAQVNEENLPTYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAPYMLPEDVFVEKPRLS-QNLDGVVIEFLFRQSKISEVLGGSGYNSDRLCL--PYIPQLTDE------------DRLSKRKSIGETISLQVEVESRNS-PEKEERVPAEEITYETLKKAIVDSVAVEEQE--RERQRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIFEITIRPPPSPSGTISAAYGQPQNHSIPVYEMKFPDLCVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2G0-1", "uniprot_id": "EFR3B_HUMAN", "id": "Q9Y2G0-1", "name": "Protein EFR3 homolog B", "aln": "-------------------------------------------------------MYGVCGCCGALRPRYKRLVDNIFPE--DPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHRYGYVCIAMEALDQLLMACHCQS-INLFVESFLKMVAKLLESEKPN----LQILGTNSFVKFANIEEDTPS---------YHRSYDFFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQH------VEEAESRSPSPLQAPEKEKESPAELAERCLRELLGRAAFGNIKNAIKPVLIHLDNHSLWEPKVFAIRCFKIIMYSIQPQHSHLVIQQLLGHLDANSRSAATVRAGIVEVLSEAAVIAATGSVGPTVLEMFNTLLRQLRLSIDYALTGSYDGAVSLGTKIIKEHEERMFQEAVIKTVGSFASTLPTYQRSEVILFIMSKVPRPSLHQAVDTGRTGENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTALMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLSDISVLKLKVDKCSRQDTVFMKKHSQQLYRHIYLSCKEETNVQKHYEALYGLLALISIELANEEVVVDLIRLVLAVQDVAQVNEENLPVYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAPYMLPEDVFVERPRLS-QNLDGVVIELLFRQSKISEVLGGSGYNSDRLCL--PYIPQLTDE------------DRLSKRRSIGETISLQVEVESRNS-PEKEERVPAEEITYETLKKAIVDSVAVEEQE--RERRRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIFEITIRPPPSPSGTITAAYGQPQNHSIPVYEMKFPDLCVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PPK9-1", "uniprot_id": "A0A8M9PPK9_DANRE", "id": "A0A8M9PPK9-1", "name": "", "aln": "MKVYRSITRVDIILSGFDENKKMPLPSLRNFSALPDFPGPRRLLLDCSALLDHQVGGGVCGCCGALRPRYKRLVDNIFPE--DPEDGLVKANMEKLTFYALSAPEKLDRIGAYLSERLSRDVARHRYGYVCIAMEALDQLLMACHCQS-INLFVESFLTMVRKLLEADKPN----LQILGTNSFVKFANIEEDTAS---------YHRSYDFFVSRFSEMCHSSFEDPDIRTKIRMAGIRGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQQ------EEGIE-RSPSP--ETEKEKESPVELTERCFRELLGRAVYGNIKNAVKPVLMHLDNHSLWEGKTFAVRCFKIIMYSIQSQHSHLVIQQLLGHLDANSKNSARVRAGIVEVISEAAVIEASGSIGPTVLEVFNTLLKQLRLSVDYELTGSYDSFANMGTKVIKVHEERQLQESVIKTIGSFANTLPTYQRSEVMLFIIGKIPVPGMYPALGSANTGVEGSRMIQIMLLKSLLQVTAGFQSNNILTALPTSFLDPLLSFTLMEDAEIRLLVLDILISIIDRHDNRHKFSPVRIISDISILKLKVDKCSRQDNLFMKKHSHRLYRHIYLACKEDSSVQRHFESLHTLLGLICVELANEEVVVDLIRLALALQDLALT-DDTLPVYSRCAIHALSAAYLNLISQLTTVPTFCQHVHEVIESRKKLVPFLLPEDVLVESPKIP-EKLEKVEGEMLFAQAKIAEMLGGSGYNTERLAT--AYIPQITDE------------DRLSKRKSIGDTVSLQLEMESRNS-PEKEQRSTAEQITFETLKQAIVDSVNVEELE--RERRRQVVERFQTAPFEEIAAHCGARSSLLQSKLNQIFEITIRPPPSPSGSVGNGHGR--SRSVPVYEMKFPDLCVY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q5SPP5-1", "uniprot_id": "EFR3B_DANRE", "id": "Q5SPP5-1", "name": "Protein EFR3 homolog B", "aln": "-------------------------------------------------------MTGVCGCCGALRPRYKRLVDNIFPE--DPEDGLVKANMEKLTFYALSAPEKLDRIGAYLSERLSRDVARHRYGYVCIAMEALDQLLMACHCQS-INLFVESFLKMVRKLLEADKPN----LQILGTNSFVKFANIEEDTPS---------YHRSYDFFVSRFSEMCHSGYEDPDIRTKIRMAGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQS------GEGTESRSPSPLQASEKEKESPAELTERCFRELLGRAAYGNIKNAVTPVLMHLDNHSLWEGKTFAVRCFKIIMYSIQSQHSHLVIQQLLGHLDANSKSSATVRAGIVEVLLEVAAIAASGSVGPTVLEVFNTLLRHLRLSVDYELTGSYD-CTNIGTKIIKEHEERQLQEAVIRTIGSFANTLPTYQRSEVMLFIMGKVPIPGLHPTLPSIGSGPEGNRMIQVMLLKSLRQVTCGFQTTNMLTALPNSFLDPMLSFALLEDAEIRLLVLEILVSLIDRHDNLPKFSNISIISDISVLKLKVDKCSRQDNLFMKKHAQHLYRHIYLCSKEQSSVQPHFEKLYSLLALISMELANEEVVVDLIRVALALQDLALSSEEMLPVYNRCAIHALSSAYLNLISQLTTVPAFCQHVHEVIEMRQKEIPYLLPEDVFIENPKIP-KTLEKLEGDVLFQQAKITEVLGGSGYNTERLAT--PYVPQFTDE------------DRLSKRKSIGETISLQVEVDSRNS-PEKEERTPAEEITFETLKNAIVDSVGVEEQE--KERRRQVVEKFQKAPFEEIAAHCGARATMLQSKLNQIFEITIRPPPSPSGTITSSYGQTQSRSVPVYEMKFPDLCVY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IGJ0-2", "uniprot_id": "EFR3_DROME", "id": "Q8IGJ0-2", "name": "Protein EFR3 homolog cmp44E", "aln": "-----------------------------MALIRCCFEPPELPEFFDSFVQKCTDPSCCCGCCSALRPRYKRLVDNIFPV--NPEDGLVKSNMEKLTFYSLSSPDKLDRIGEYLYQKATKDINRKRYKLAEIAMEAMDLLLQACHAQTTLNLFVESFLRMVQKLLEDSNPN----LKIMATNSFVKFANINEDTPS---------YHRRYDFFISKFSSMCHS--DAASMRDSLRLAGIKGLQGVIRKTVSDDLVENIWEAEHMEKIVPSLLFNMQFCVNVMFVKKNLLASGDLTPVEDATNVTPPALAEEVLRELVGRASFGHIRSVLKPLLTHLDRHELWVPNTFAIHTFRIVMISIQPQYSYTVVETLMQHLDNNFKSSPKTRTSLAVVLSKIIAIAAGESVGPSALDIINNLLTHLRTSVS--------------TTSEITPEESQYQEALINALGEFANHHPDYQKIEIMLFIMNTVP---------DLSKKSKGDQMLQNILLKSLLKVGTQYSTVSFEKAFPASFLQPLLKMARAPHNPTRMVVMQILQALLDRHQNEQVLSSVSVK---PYPALSQEPPSRSDIIFTHKYGANIMQALIDSMALSDRVDALTSSFN-TAALLIVEMSCNETVQEFLLFILGIQQVACT-VDTLGNVHKCSLHAISIGLLVLISRVSGINNLLEYAQKIVDARREEASHFLPP--LLEPKKLAGKTFNLQLPHLAIDKLALGECLQNAGMDAQRLNTGAPYSLNQTDHPGHRHSWVESVSNQLTQRNSSADLTVYNGDVDSVSSSPGVCKKLLAPEFNFDAMKRALAEPTEAAKREQ-RERQMQIVRTFREGEFDDLMRRTEPKHDLIQNRLNELFN-SLAVERQITQSDTKSSQLQASNEKPIYETNFPELFYY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03653-1", "uniprot_id": "EFR3_YEAST", "id": "Q03653-1", "name": "Protein EFR3", "aln": "---------------------------------------------------------MQLSMRMMFTPKHQKLVNQCYPTGRTTDKKPKSSETSYLLYYVNSRRSKLEKVSTYLIKRSTSDLNHRRIGNIAVTLDLMNKIVLHCKENL--NVFVKDFLYIMNKVLSNNNFNNDVSVVELIELAFSSICQNLDDVLCNGDMEFVQLYQNFVDLFFKIVTERIHNDDMLLKCCIDISNTNSVSSNPQLNHFVSKSVAYTISKFQERNPKFKTLSLEAALESN---LGKRLSRTQTRTIGLDKAAEDNHDLSVKALQSYFNTTETDKLNLSIRTLLRCLQSTPNKE-------LLEFVCNGIPVQLRYIVILLLVRQLSDKDKN---VNPIVSLKLMSSLLVSDVSIVGLSVLDIMRKLLNFQLKNATN---------KEVVAQSCITMTDLNHKTYYAEQTSDMLYELLLKLKSDTVKDVEKNAVVEDIDFLVEHITQPSISLELFIDLAHYMKNHIICLFN--IVETEVPSSILFSKL-YSLLRELDSHGVQKEMMEEIFDKYGKMALLS---------GLNYFLENVSEPEYTYYSYHLQAANFLKLNDYKSQTEYKMQTRTLFTKEDLLSYYSDTGSNKYSKKGAQILLSRDNQISTSDLLSDS--QVRTTPLEYKNVPNAIFSNGKAVYDNNDFAAKQNKFDNSIDDNIEEANDTVISDANAKGSIYRFVAEDARSWKTMRATAPKVSDLKK-------------------------TMNEKNIPNNMKRDGSFRGSQS---VKSRVTNITFLLNELKTFSDDANKIKDPDEENIVGLDKIDVARSNSLRLAPISSLSDRSSIGNRKSFLQKTATGENQNDDFKDANEDLHSLSSRGKIFSST-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *::::**:: :* .:. .:: . * :* * .**:::. ** :: *: ::* :::: :: :: *: : *:**:.** :: *:*. .: * : : :* .:.: :*. . *:. *:*.. .:. *. . .: :. . : :.: *...: .* . :. : . :* :: : : *: . ::. .. : .::. : .:* *: :.:: .* * : *: *: :*. : :. ... : : . : :* :.*:::..** . : : : . ..: : : : : . .: : :: :. . . .* .:* * : . : . ::: ::*:: : :* : *. : : : . . : *: . . : :. . * : : : . : :.. :.: : : :. . . . . : : :. . . * :... : : .. . .* .: : : :* :. . : . : : : : . : .: . : : : . . . ::. . ", "identical_positions": 54, "similar_positions": 251, "identity": "5.92%" }, { "cls_id": "homologset.agr.MGI:2444853", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2N8-1", "uniprot_id": "IFT56_RAT", "id": "Q5U2N8-1", "name": "Intraflagellar transport protein 56", "aln": "MMLSRAKPAVGGESPHTD---------KRKKKGRKIPKLEDLLSQRDFTGAITLLEFKRHVGEQEE--------DTNLWIGYCAFHLGDYKRALEEYENAAKEENCN-PEVWVNLACTYFFLGMYKQAEAAGFKAPKSRLQNRLLFHLAHKFNDEKKLMNFHQNLQDIK--EDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGKAAEAELKSLMDNASSPFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEVFLLIQSEKLKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKMGQFYYSAKAFDVLERLDPNPEYWEGKRGACVGIFQMILAGRE---PKETLREVLHLLRSTGNTQVEYIIRIMKKWAKENRVPI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BS45-1", "uniprot_id": "IFT56_MOUSE", "id": "Q8BS45-1", "name": "Intraflagellar transport protein 56", "aln": "MMLSRAKPAVGGESPHTD---------KRKKKGRKIPKLEDLLSQRDFTGAITLLEFKRHVGEQED--------DTNLWIGYCAFHLGDYKRALEEYENATKEENCN-PEVWVNLACTYFFLGMYKQAEAAGFKAPKSRLQNRLLFHLAHKFNDEKKLMNFHQNLQDIK--EDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGKAAEAELKSLMDNASSPFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEVFLLIQSEKLKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKMGQFYYSAKAFDVLERLDPNPEYWEGKRGACVGIFQMILAGRE---PKETLREVLHLLRSTGNTQVEYIIRIMKKWAKENRVPI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AVF1-1", "uniprot_id": "IFT56_HUMAN", "id": "A0AVF1-1", "name": "Intraflagellar transport protein 56", "aln": "MMLSRAKPAVGRGVQHTD---------KRKKKGRKIPKLEELLSKRDFTGAITLLEFKRHVGEEEE--------DTNLWIGYCAFHLGDYKRALEEYENATKEENCN-SEVWVNLACTYFFLGMYKQAEAAGFKASKSRLQNRLLFHLAHKFNDEKKLMSFHQNLQDVT--EDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGRAAEAELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEAFLLIQSEKMKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKMGQFYYSAKAFDVLERLDPNPEYWEGKRGACVGIFQMIIAGRE---PKETLREVLHLLRSTGNTQVEYMIRIMKKWAKENRVSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PR66-1", "uniprot_id": "IFT56_DANRE", "id": "Q5PR66-1", "name": "Intraflagellar transport protein 56", "aln": "MLLSRMKPAVGGEASTSSNEK------KRKNKSKKIPRLEDYLNQRDYLGALTLLEFQRNSGVSVE--------HADLWTGFCAFHVGDHKRAMEEYKALTLRPDCP-VDVWVYLGCALFFLGLYKEAEEAALKGSKTQLQNRLLFHLAHKFNDEKKLMGFHQNLEDVT--EDQLSLASIHYMRSHYQEAIDIYKRILLQNREFLALNVYVALCYYKLDYYDVSQEVLAVYLQSIPDSTIALNLKACNHFRLYNGKAAETELKNLIDISSSSFQFAKELIQHNLVVFRGGEGALQVLPPLIDVISEARLNLVIYYLRQDDIQEAYKLIKDLEPTTPQEYILKGVVNAALGQEIGSRDHLKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFEDVLIYLNSVKSYFYNDDTFSFNYAQAKAALGNYREAEELFLLIQNEKIKSDYVFQSWLARCYIMNQKPRQAWELYLRMETSSDPFSLLQLIANDCYKMGQFYYAAKAFDALERLDPNPEYWEGKRGACVGIFQLILAGRE---SREILKEVLPMLRSTGNPQVEYIIRIMKKWAKDNRVAL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF41-1", "uniprot_id": "Q9VF41_DROME", "id": "Q9VF41-1", "name": "", "aln": "MILSRGKTDSASSRNASGGPGSGLGVGRQARKTPAPASLEDFIIRRDYTGARAFLEFANDDEDEEEGAHGSKQSQVDQWIAFCNFHLGDYQQALAQYKAIQQGSSTPDGKLDLNLAVCMFYLGLYEEAQQLMANAADNPLKQRLLFHLAHKLGNEEEWSQLQEELQDSSSLEQQLSLASMHYMRAHYQEAIDVYKRVLVDNKEYQAINVYLALCFYKLDYYDMSQEVLDVYLSQHGDSTIAINLKACNRFRLFNGRVAEQEIKNIADNG----TFGADLLRHNLVVFRNGEGALRVLPGLLNIIPEARLNLAIYYLKQGDVQEAHALMKELQPTSPHEYILKGVVHAALGQQLGSKEHIKTAQQNLHLVGSSATECDTIPGRQSMASAFFLYEQFEEVLVYMNSIRSYFVNDDVFNYNFAQAKCATGYYKEAEELLMQISDMDIKNQHTYCMILAKCHIHCGHPELAWNVFITRDTNAEAFILLQLIANECYKCAEFWVAAKAFDMLEKLDPSPENWEGKRGACAGVLFALCTKAQRGRPGGGISEVIGILRDSSNSQAEAMIKTIRKHINHFK---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*** *. . :. :: .* . **: : :**: ** ::*** .. . : ..: * .:* **:**:::*: :*: . .: : *. *:**:*::*: :.... *::*********:.:*:: ::::*:* . *:******:****:*******:***:*::*:*: *:***:***:*******:***** ***.. *****:******:***:**:.** *:*.: * . *. :*::*******.*****:*** *:::*.******.****:*.*:***: *:*:*:**:*:********:*****::**::*:* *** ::***.**:*********.***.*** :**::**:*:**.:*** *** *.:*:****.* * *.** :: *.. .:*.:: : **:*:* :*. **:::: :*..:.* *******:*** .:*: :***** **:***.** ********.*:: : : : . : **: :**.:.*.*.* :*: ::* :. : ", "identical_positions": 265, "similar_positions": 179, "identity": "45.93%" }, { "cls_id": "homologset.agr.MGI:2444854", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80ZD5-1", "uniprot_id": "AMGO3_RAT", "id": "Q80ZD5-1", "name": "Amphoterin-induced protein 3", "aln": "MAWLVLLGLLLCMLGAGSGTSDLEGVLPPDPHNCPNKCVCAADVLSCAGRGLQDLPAALPATAAELDLSHNALKRLHPGWLAPLSRLRALYLGYNKLDVLGRGVFTNASGLRILDLSSNLLRRLRTYDLDGLEELEKLLLFNNRLMHLDLDAFQGLSMLSHLYLSCNELSSFSFNHLHGLGLTRLRTLDLSSNWLGHVSVPELAALPTFLKNRLYLHNNPLPCDCSLYHLLRRWHQRGLSALHDFEREYTCLAFKVAESRVRFFEHSRVFKNCSVAAAPGLELPEEELHTHVGQSLRLFCNTTVPAARVA--WVSPKNELLVAPGSQDGSIAVLADGSLAIGRVQEQHAGLFVCLASGPRLHHNQTLEYNVSVHKPRPEPEAFNTGFTTLLGCIVGLVLVLLYLFAPPCRGCCRCCRRACRNRCWPRASSPLQELSAQSSVLSTTPP---DAPSRKASVHKHVAFLEPGKKGLNGRVQLAVAEDFDLCNPMGLQLKAGSESASSTGSEGLMMS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C2S7-1", "uniprot_id": "AMGO3_MOUSE", "id": "Q8C2S7-1", "name": "Amphoterin-induced protein 3", "aln": "MAWLVLSGILLCMLGAGLGTSDLEDVLPPAPHNCPDICICAADVLSCAGRGLQDLPVALPTTAAELDLSHNALKRLHPGWLAPLSRLRALHLGYNKLEVLGHGAFTNASGLRTLDLSSNMLRMLHTHDLDGLEELEKLLLFNNSLMHLDLDAFQGLRMLSHLYLSCNELSSFSFNHLHGLGLTRLRTLDLSSNWLKHISIPELAALPTYLKNRLYLHNNPLPCDCSLYHLLRRWHQRGLSALHDFEREYTCLVFKVSESRVRFFEHSRVFKNCSVAAAPGLELPEEQLHAQVGQSLRLFCNTSVPATRVA--WVSPKNELLVAPASQDGSIAVLADGSLAIGRVQEQHAGVFVCLASGPRLHHNQTLEYNVSVQKARPEPETFNTGFTTLLGCIVGLVLVLLYLFAPPCRGCCHCCQRACRNRCWPRASSPLQELSAQSSMLSTTPP---DAPSRKASVHKHVVFLEPGKKGLNGRVQLAVAEDFDLCNPMGLQLKAGSESASSTGSEGLVMS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86WK7-1", "uniprot_id": "AMGO3_HUMAN", "id": "Q86WK7-1", "name": "Amphoterin-induced protein 3", "aln": "MTWLVLLGTLLCMLRVGLGTPDSEGFPPRALHNCPYKCICAADLLSCTGLGLQDVPAELPAATADLDLSHNALQRLRPGWLAPLFQLRALHLDHNELDALGRGVFVNASGLRLLDLSSNTLRALGRHDLDGLGALEKLLLFNNRLVHLDEHAFHGLRALSHLYLGCNELASFSFDHLHGLSATHLLTLDLSSNRLGHISVPELAALPAFLKNGLYLHNNPLPCDCRLYHLLQRWHQRGLSAVRDFAREYVCLAFKVPASRVRFFQHSRVFENCSSAPALGLERPEEHLYALVGRSLRLYCNTSVPAMRIA--WVSPQQELLRAPGSRDGSIAVLADGSLAIGNVQEQHAGLFVCLATGPRLHHNQTHEYNVSVHFPRPEPEAFNTGFTTLLGCAVGLVLVLLYLFAPPCR----CCRRACRCRRWPQTPSPLQELSAQSSVLSTTPP---DAPSRKASVHKHVVFLEPGRRGLNGRVQLAVAEEFDLYNPGGLQLKAGSESASSIGSEGPMTT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B8R9-1", "uniprot_id": "A0A8M2B8R9_DANRE", "id": "A0A8M2B8R9-1", "name": "", "aln": "---------MLCAQGVAAPLMLSSFLLQLVRANIPSGCLIASDILSCTNLGLDQVPLELPITVATLDLNHNRLEHLEEGCFAGLPKLDTIRLAHNQLSKLTPGTFRNTSKIHHLDLSSNQLNIIEQHYFQDLVAIEELLLYNNRIVRVESKALSGLSNLRKAYLSHNRLTDFPFFSIH--EHPNLNTLDLSSNRMPNLPIEEIGALEESVQQALFLHNNTLICECSMYSMFRHWEQRGFASVREFWEEHTCLLYGEQRASVRFLQHVRFFENCTVKRLA----QTDSKTAEAGKSVMLNCMTSLSGRNVTYWWVSPHKEYIVPPGNNN-TLRMYANGSLEILQPRIEDSGLYLCMAQNPQESHNQTFEVNLTVTIYHQEVEPFNTGFTTLLGCVVSLVLVLMYLYLTPCR-------CWCRKQPLPATPSPANECSAQSSILTPTPPATTEGPGRKVSNNKHVVFLEPIKEAQNGRPRAALALEH----PKLAVTRSDADSVTSVFSDTTIVP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** .. . . * * *: *:*:***:. **:::* ** :.* ***.** *::*. * :* * :* :: * :*:*. * *.* *:* :: ****** *. : : ::.* :*:***:** ::::: .*: ** * : **. *.*:.*.* :* ..* ******* : ::.: *:.** ::: *:****.* *:* :* ::::*.***::::::* .*:.** : : ***::* *.*:**: : : .*:*: * * *::.. .:: ****::* : .*...: :: : *:*** * . : :.:*:::*:* .*: **** * *::* : * *.*********** *.*****:**: .*** ** : * :.** :* *****:*:.*** :.*.**.* :***.**** :.. *** : *:* :. * ::.::*.:* *: : .", "identical_positions": 182, "similar_positions": 163, "identity": "35.48%" }, { "cls_id": "homologset.agr.MGI:2444855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8N4-1", "uniprot_id": "KLH20_RAT", "id": "D3Z8N4-1", "name": "Kelch-like protein 20", "aln": "MEGKPMRRCTNIRPGETGMDVTSRCTLGDPNKLP----EGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGFLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2M5-1", "uniprot_id": "KLH20_HUMAN", "id": "Q9Y2M5-1", "name": "Kelch-like protein 20", "aln": "MEGKPMRRCTNIRPGETGMDVTSRCTLGDPNKLP----EGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGFLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VCK5-1", "uniprot_id": "KLH20_MOUSE", "id": "Q8VCK5-1", "name": "Kelch-like protein 20", "aln": "-----MRRCTNIRPGETGMDVTSRCTLGDPNKLP----EGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQITVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGFLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTIAPMGTRRKHLGCAVYQDMIYAVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVFDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9QC58-1", "uniprot_id": "E9QC58_DANRE", "id": "E9QC58-1", "name": "Kelch-like protein 20", "aln": "------------------MDITSRCTLGDPNKLP----EGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDERAMELLIDFAYTSQVTVEEGNVQTLLPAACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFMLLPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGSDPLIKSDEECRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAISSVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAPTSTCRTSVGVAVLGGYLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLYAVGGSDGTSPLNTVERYNPQENRWHTVAPMGTRRKHLGCAVYQDMIYSVGGRDDTTELSSAERYNPRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVYDPDANTWRLYGGMNYRRLGGGVGVIKMTHCESHIW----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUU5-1", "uniprot_id": "KLHDB_DROME", "id": "Q9VUU5-1", "name": "Kelch-like protein diablo", "aln": "MGDLPGSGSTAQPRDAAVTGTGGNSTAGGGSSVGSTAVDRPPSPARLSHTSEKHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAIASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQCPLNTVERYDPRHNKWVAVSPMSTRRKHLGCAVFNNYIYAVGGRDDCMELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGSAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVMRAPQTENYMWCENSFKQPNS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ...* *. ..: : *.***:.: *:***: ** :*:**:********* **.:**:**********.** ******* *******.******.********.**::: ***.**************.***: ***********:**************************************:***..**:***.*****************:*:**.: *** :*.*********************** *::*** ******************************* * ****************:****:*****:*:***.**********:**:***********.*****:*****:*****.*****::**********.*:**********.*** ***********::**.*:*****************:***** .********:*:.*:* :::**.**********::: **:****** ********** ** ***:******************* *******::*******:**::* *** * ************:: .: *.::* ", "identical_positions": 462, "similar_positions": 92, "identity": "74.16%" }, { "cls_id": "homologset.agr.MGI:2444862", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1A5B6-1", "uniprot_id": "TBC25_MOUSE", "id": "A1A5B6-1", "name": "TBC1 domain family member 25", "aln": "MRPPAQARWEGQGPTAPLRLRSGARWGRGRPHCWVYVRVRVTIGYHLDRDDSGGMATTSAASDSACSAAPPPVGGAQAAAAVEEEEREVVRVRVKKCESFLSPEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLARDRLGQETFLSLLSDWDLSTAFATASKPYLQLRVDIRPSEDSPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVADTGFGSH----------RGRPVRQRHMLRPAG--------------------GGGGAFEDAVVHLAASSQGPSG------------GGR-------------------------------LLRQASLDG------LQQLRDNMGL-----RKDHLVQLSHPATLISS-----KSLSEPLLNSPDPLLSTSSRPDSPSSSSPPSTQEAS----PSGDIAVGSPLMQEVGSPRD---PGKPVPPPP-------------------------------------------------------PMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGAEATAPS----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ALA8-1", "uniprot_id": "A0A8I6ALA8_RAT", "id": "A0A8I6ALA8-1", "name": "TBC1 domain family member 25", "aln": "------------------------------------------------------MATTSAASDLACSAAPSPVGGASAAAAVEEEEREVVRVRVKKCESFLSPEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLARDRLGQEAFLSLLSDWDLSTAFATASKPYLQLRVDIRPSEDSPLLEDWDIISPKDVIGSDVLLADKRSSLTTAALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVADTGFGSH----------RGRPVRQRHMLRPAG--------------------GGSSAFEDAVVHLATSSQGPSS------------GGR-------------------------------LLRQASLDG------LQQLRDNMSP-----RKDLLVQLSHPATLISS-----KSLSEPLLNSPDPLLSSSSRPDSPSSSSPPSTQEAS----PSGDVAVGSPSMPEVGSPRD---PGKSVPPPP-------------------------------------------------------PMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGAEATAPS----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3MII6-1", "uniprot_id": "TBC25_HUMAN", "id": "Q3MII6-1", "name": "TBC1 domain family member 25", "aln": "------------------------------------------------------MATASGASDLSGSGAPPPGVGAQAAAAAEEEEREVVRVRVKKCESFLPPEFRSFAVDPQITSLDVLQHILIRAFDLSGKKNFGISYLGRDRLGQEVYLSLLSDWDLSTAFATASKPYLQLRVDIRPSEDSPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILTQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRANPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVADAGFGGH----------RGWPVRQRHMLRPAG--------------------GGGSTFEDAVDHLATASQGPGG------------GGR-------------------------------LLRQASLDG------LQQLRDNMGS-----RRDPLVQLPHPAALISS-----KSLSEPLLNSPDPLLSSFSHPDSPSSSSPPSTQEAS----PTGDMAVGSPLMQEVGSPKD---PGKSLPPVP-------------------------------------------------------PMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRARALFADYLQSEVWDSEEGAEATAAS----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0S696-1", "uniprot_id": "B0S696_DANRE", "id": "B0S696-1", "name": "", "aln": "--------------------------------------------------------------------------------MSVEEERGVVRVKVKKCEGVLPVEFRSFAVDPQITSLEVLQHILIRAFELNGKRNFGISYLSRDRAGVEVYVSLLSDWDLDAAFVSAAKPYLQLKMDIKPSEDSPVLEDWDIISPKDVIGSDQLQGEKRS-LASAALPFTQSLLSQVGRTLSRVQQALSWSYGEEVKPFKPPLSDAEFHNYLNSQGQLSRPEELRLRIYHGGVESSLRKVVWRYLLNVYPDGLTGQERMDYMKRKTREYDQLKSEWTARVSSEELEFIRGNVLKDVLRTDRAHPYYAGSEDSPHLTALTDLLTTFAITHPQVSYCQGMSDIASPILAVMDNEAHAFICFCGIMKRLEGNFRPDGQLMSIKFQHLKLLLQYSDPEFYSYLVSKGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPETEVELLG-PAFEADQSDGSHNVDMEEMEEKQTERQRRRHMLRPSREEADGERNLVMEEERGPRKEGEGEYDVESMVRNDIPAQPPSFEKQGSFGEFKYYNGRTEDSFEVNENDSSDPTLSPVQFQSAHSTLPFSVRQSTEESEDDPGEQEPLINNLTPSSPGQRDSPNGQAASPLSTLPSGLPNWKSSSNQSSNSASSWRTASPDALSKCTSSSSSGEKALSPDKPSGGFASSQPVLNGTGAQSPSVVPGKSLLASPSQGYNHSLLSSPVLSFGKSPSLPKAFSSNLPSPCRPTGSGVSSPNTNKPEGGGIKPCSLPPPQEFGKGNPFMLFLCLSILLEHRDHIIKNSLDYNELAMHFDRLVRRHNLGRILQRAKALFADYLQSEVWDSEEGDEVSLDSPTTAATSPQTPSTRPPFLNVQPSQGAFPNSTYNLANTIPSPTTPIALSPSAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** ****:*****..*. **************:**********:*.**:*******.*** * *.::********.:**.:*:******::**:******:**************** * .:*** *::********:*:*******:***.*******:**************.*** :*******************.********************:*********:***:******: *...*:*****..*****************.**.*** ** *****:*:*************:*********:*.***:********* .**:***: *: ** ******:::**:**.** . ****************************************** ****:* *: ** . *.* : *:******: * . ::: : .:* *. .** :**:: :. : * :*: * . * . * : :.* ** *: **... :: . . * .:**..* ::* *:*..* ..* : .*: ***.: . * * .********:**********:*********::*.***************:*:***:*:**:***************** *.: * ", "identical_positions": 452, "similar_positions": 128, "identity": "47.83%" }, { "cls_id": "homologset.agr.MGI:2444878", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92730-1", "uniprot_id": "RND1_HUMAN", "id": "Q92730-1", "name": "Rho-related GTP-binding protein Rho6", "aln": "------------------------------------MKERR--APQPVVAR---------------------CKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLET-EEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISST---------FKKEKAKSCSIM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BLR7-1", "uniprot_id": "RND1_MOUSE", "id": "Q8BLR7-1", "name": "Rho-related GTP-binding protein Rho6", "aln": "------------------------------------MKERR--APQPVVVR---------------------CKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLET-EEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETMDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSETSIHSIFRTASMVCLNKSSPVPPKSPVRSLSKRLLHLPSRSELISTT---------FKKEKAKSCSIM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L6G2-1", "uniprot_id": "A0ABK0L6G2_RAT", "id": "A0ABK0L6G2-1", "name": "", "aln": "------------------------------------MRGRSGTARGSCGGE---------------------ESRPLWREYSSSPASLLRPLLSACRNSEAAAGRLRRRIIDVLE-DGGDSNCRACPRWGSPYYDNVRPLCYSDSDAVLLCFDISRPETMDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSETSIHSIFRTASMVCLNKPSPVPPKSPVRSLSKRLLHLPSRSELITST---------FKKEKAKSCSIM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00246-1", "uniprot_id": "RHO4_YEAST", "id": "Q00246-1", "name": "GTP-binding protein RHO4", "aln": "MNTLLFKRKGGNCGNESNIVSQGSPSSSNLPESPGTLDEKNLPRLPTPFARSLSTIPSYEQMKRTNKLPDYHLKIVVVGDGAVGKTCLLISYVQGTFPTDYIPTIFENYVTNIEGPNGQIIELALWDTAGQEEYSRLRPLSYTNADVLMVCYSVGSKTSLKNVEDLWFPEVKHFCPSTPIMLVGLKSDLY-EADNLSDLVEPSSAES-------LAKRLGAFAHIQCSARLKEN-IDEVFETAIHTLLS-DSLYAPREPTHTIKNPFKRNTTRSDIDSSTGDTSVSISGTKRLRKNKCIIM", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . : : . :.:* . . :.. : : : *. *..:***.*:::*.:::*:.:. ::... . * .*: .:**** ::*:* *:** : ..* :* . ..* :**:*** ::: ** .*. *..:*.** *. * . :.*.:::.: : : .:**:: ::* *: : :.* **", "identical_positions": 45, "similar_positions": 89, "identity": "14.95%" }, { "cls_id": "homologset.agr.MGI:2444879", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TP54-1", "uniprot_id": "RIPR2_RAT", "id": "Q7TP54-1", "name": "Rho family-interacting cell polarization regulator 2", "aln": "MQHCLEQSDITQYQQYYSSWCDARALGPRLSPVALSLLVGRNEHRLSAEPEVHRSQGRCVGVEVPREDINYLSTTCKPEIKSRNLKEDSEDQGRLPTRLPEIMLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSRQVLGVSPGITRAPSKDVYCKPGYACRVEFLLCKAFSKQTCNSFIENASALKKPQAKLKKMHNLGHKNTNTP---KEPQPKRVEEVYRALKNGLDEYLEFHQTELDKLTAQLKDMKRNSRLGVLYDLDKGVL----------YDLDKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLSEINRSYKEYTENMCTIEAELESLLGEFSIKMKGLAGFARLCPGDQYESMDGPNPYQRQQGEVYFSLLATRRIGDGSCLSKGARIFMKYGRQRWKLKGKIEVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVDINDLGTIKLNLEITWYPFDVEDTTPSSGPGNKTAALQRRMSMYSQGTPETPTFKDQSFF--------------------------------------------------SNLPDDIFESG-NAAEEKRPLSLSFSDLQDGDCVFTSSSTTSPSSSHSAHPEITITPAELTHSS---LSSQNEGTEDSSSASSRNSLGEDHEPKSHSKS-DTVEPKKPS---------VDARSGTESLFLENSVAEALLQE---SDEASELKPVELDTFEGNITKQLVKRLTSAEGPITTNKLFFEGSVGSESEAGRSFLDGSLEDAFNGLFLALDPHKEQYKEFQDLNQEVTHLDDVLKCKPAGSRSRSSSLSLTVESALESFDFLNTSDFDEEEEDGDEVCHVGGGADSVFSDTETEKSG--SVHPEARGHLSEALTEDTGVGTSVAGSPLPLTTGNESLDITIVKHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQVLVLQKLAAVSDENLGNITSVVEAIPEFHKKPSLLSFWTKCCSPSGVYHSSAAHLIKQLEASFARNINKDYPGLAEPVFRTLVSQILDRAEPLLCS-GLSSEVITVFQYYSFLTSHGVSDLETHLGQLARQVAMVQTLQSLRDEKLLQTMSDLAPSNLPAQQEVLRTLALLLTKDDNEVSEAVTLYLAAASKNEHFREKALLYYCEALTKTNLQLQKAACLALKSLEATESIKMLVTLCQSDTEEIRTVASETLLSLAPYSGSAMTSQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDPDDVALEGNERGGRALFQDVQKPSQDEWGKTLEAMEAALALEKNLNQALLDLHALGSARTDPHLCDFLESHFLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGVAQASLGEYLFERLTLKHD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U16-1", "uniprot_id": "RIPR2_MOUSE", "id": "Q80U16-1", "name": "Rho family-interacting cell polarization regulator 2", "aln": "---------------------------------------------------------------MPPG--------------TKRLRALGAFSAGLPTRLPEIMLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSR---------------------------------------CNSFIENASALKKPQAKLKKMHNLGHKNNNTP---KEPQPKRVEEVYRALKNGLDEYLEFHQTELDKLTAQLKDMKRNSRLGVLYDLDKQIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLSEINRSYKEYTENMCAIEAELESLLGEFSIKMKGLAGFARLCPGDQYE------------------------------------IFMKYGRQRWKLKGKIEVNGKQSWDGAETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVDINDLGTIKLNLEITWYPFDVEDTTPSSGPGNKTAALQRRMSMYSQGTPETPTFKDQSFFRWLR--------LSVLSALRDTFFATLHHNHSVGDLPSLSLNPKALLEFYSNLPDDIFESG-KAAEEKRPLSLSFSDLQDGDCVFTSSSATSPSSSHSAHPEITITPAELTHSS---LSSQNEGTEDSSSASSRNSLGEDHEPKSHPKS-DTVEPGKPG---------VATRSGTESLFLESSVAEALLQE---SDEASELKPVELDTFEGNITKQLVKRLTSAEGPVTTDKLFFEGSVGSESEAGRSFLDGSLEDAFNGLFLALDPHKKQYKEFQDLNQEVTHLDDVLKCKPAGSRSRSSSLSLTVESALESFDFLNTSDFDEEEEDGDDVCHVGGGADSVFSDTETEKSGYRSVHPEARGHLSEALTEDTGVGTSVAGSPLPLTTGNESLDITIVKHLQYCTQLIQQIVFSSKTPFVARSLLEKLSRQVLVMQKLAAVSDENLGNITSVVEAIPEFHKKLSLLAFWTKCCSPSGVYHSSAARLIKQLEASFARSINKDYPGLAEPVFRTLVSQILDRAEPLLSS-SLSSEVITVFQYYSFFTSHGVSDLETYLGQLTRQVAMVQTLQSLRDEKLLQTMSDLAPSNLPAQQEVLRTLALLLTRDDNEVSEAVTLYLAAASKNEHFREKALLYYCEALTKANLQLQKAACLALKSLEATESIKMLVTLCQSDTEEIRTVASETLLSLGEDG----------------------------RLAYEQLDK---FPRDCVKVGG--RHG---------------------TEVATAF--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y4F9-1", "uniprot_id": "RIPR2_HUMAN", "id": "Q9Y4F9-1", "name": "Rho family-interacting cell polarization regulator 2", "aln": "------------------------------------------------------------------------------------------------------MLVGSQSFSPGGPNGIIRSQSFAGFSGLQERRSR---------------------------------------CNSFIENSSALKKPQAKLKKMHNLGHKNNNPP---KEPQPKRVEEVYRALKNGLDEYLEVHQTELDKLTAQLKDMKRNSRLGVLYDLDKQIKTIERYMRRLEFHISKVDELYEAYCIQRRLQDGASKMKQAFATSPASKAARESLTEINRSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFARLCPGDQYE------------------------------------IFMKYGRQRWKLKGKIEVNGKQSWDGEETVFLPLIVGFISIKVTELKGLATHILVGSVTCETKELFAARPQVVAVDINDLGTIKLNLEITWYPFDVEDMTASSGAGNKAAALQRRMSMYSQGTPETPTFKDHSFFRWLHPSPDKPRRLSVLSALQDTFFAKLHRSRSFSDLPSLRPSPKAVLELYSNLPDDIFENG-KAAEEKMPLSLSFSDLPNGDCALTSHSTGSP--SNSTNPEITITPAEFNLSS---LASQNEGMDDTSSASSRNSLGEGQEPKSHLKEEDPEEPRKPASAPSEACRRQSSGAGAEHLFLENDVAEALLQE---SEEASELKPVELDTSEGNITKQLVKRLTSAEVPMATDRLLSEGSVGGESEGCRSFLDGSLEDAFNGLLLALEPHKEQYKEFQDLNQEVMNLDDILKCKPAVSRSRSSSLSLTVESALESFDFLNTSDFDEEE-DGDEVCNVGGGADSVFSDTETEKHSYRSVHPEARGHLSEALTEDTGVGTSVAGSPLPLTTGNESLDITIVRHLQYCTQLVQQIVFSSKTPFVARSLLEKLSRQIQVMEKLAAVSDENIGNISSVVEAIPEFHKKLSLLSFWTKCCSPVGVYHSPADRVMKQLEASFARTVNKEYPGLADPVFRTLVSQILDRAEPLLSS-SLSSEVVTVFQYYSYFTSHGVSDLESYLSQLARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALLLTREDNEVSEAVTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKMLVTLCQSDTEEIRNVASETLLSLGEDG----------------------------RLAYEQLDK---FPRDCVKVGG--RHG---------------------TEVATAF--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1LU99-1", "uniprot_id": "RIPR2_DANRE", "id": "Q1LU99-1", "name": "Rho family-interacting cell polarization regulator 2", "aln": "----------------------------------------------------------MAFPDITEDDLN---------ELMREEAEDVFDDDGVSSRFPDIMAAG--THSPGGPNGIIRSQSFAGFSTLQERRSR---------------------------------------CNSFMGNSAVQKKPISKPRKPHLSGHKSSSSSSSSREPQPKRVEEVYSALKQGLDEYLEVHQTELDKLTSLMKDMKRNSRLGVLYDLDKQIKTIERYMRRLEFHISKVDELYEGFCIQRRLRDGASKMKQAFTASPSTKGTRESLAEVNRRYKEYTENMSTFEGELENLLGEFHIKMKGLAGFARLCPGDQYE------------------------------------IFMRYGRQRWKLKGKIEGNSKQSWDGEEMIFMPLISDLINIKVTELKGLATHVLVGSVICETKDLFTAMPQVVAVDVNDLGTIKLNLEVAWFPFDVEDLTLSSGNVSKATALQRRVSVYSQGTPETPTFQDTSFFKWQPRRWEG-QRLSFLHTLRETLIEKLRRSRSFGDLAALRPRSRSSLEVYSTLPDDVFENGGCGVAECKRLSFTFSD--------TSTSSPVP---VQSNPEITVTPPETDPSSEPPPTSEEQLVEEECVEEDCGSISVSVSVSDPDLEWDQVETQGPETG------SVALSLCSESQLSAVGPEDVVFLEPNVSDEALELKPVELDGEEGSLTRQLVRRLTSSDMLPETSALSWAG------ENSRTFMESSLEEVIQSLLLRLESLGQRCGELQDLEQEVMRLEDLLKCRVHAHRSRSSSLSLTVESALESFDFLNTSDFDDDD-TGDDAGTLSR---AVFFDMESERMG-SGQHPEARGHLSEALTEDTGVGNSVAGSPLPLTTGNENLDVAVVIHLQYCNHLIQLLT-SGGSQLQHKTYLHKLATQTLLLEELSERNFDRPSSCTSVPDVLPGLVERPALMSLWSDCSG--GLFHTTLDRVLKHMHLSFALGLQQVLPHSPDSVIKMVVNEMMDRSELASSSTSPAQDVITVFQFHRYIVEHCITDMEQHLLDLAKEVMLEEALSCGDPERSLKELKKVSITCLQPRSQTLLAVAGLLTTDDPEVMKATTDFLSSAASHQPFRSKAVDCYTQALSESELHTQRAACAALSCLQAVESIDAVILLCDSVDEELRQIAIETLLTFGEDG----------------------------RLAYEQLDT---VPREMVRLGT--RRG---------------------NAVTTSF--------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .* :.****************** ******* ****: *::. *** :* :* * ***..... :*********** ***:*******.*********: :***************** : :.:.*******.:******:**********::**::*.:****:*:** :*******.::* ***.***** ******************* ***:************* *.****** * :*:*** .:*.************:***** ****:**:* *******:***********::*:****** * *** .*::*****:*:***********:* *** *.****:**.* .. * **::*** ** *: * .::****:**.* ** :*::: :: . .. .*:. . . .. . * *. * :* : . :.:: * *:** ******** **.:*:***:****:: *. * * * *:*::.***:.::.*:* *:. :: *:***:*** .*:*:***: ***************************::: **:. :. :** * *:*: . . *******************.**************.**:::* *****.:*:* :. *. : : :: *.**: * ::::*: . :. .. :** :.:* : :: :*:::*:.*.. *::*:. :::*::. *** ::: * .:.*:: :*.:::**:* .* . :.:*:****:: ::..* ::*:* :* :*:::* : ::*.. *: *: :..:: : * .:.:.* ::* *** :* ** :*.* :*::*:.:: **.**: * :**::::*: *:*** **. *:*.***. :: **:* **:* :* ****::. . * :* *. . : * : * * .: :: ", "identical_positions": 504, "similar_positions": 285, "identity": "36.18%" }, { "cls_id": "homologset.agr.MGI:2444881", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RB11-1", "uniprot_id": "M0RB11_RAT", "id": "M0RB11-1", "name": "Choline/ethanolamine transporter FLVCR1", "aln": "MARPDDEVGPAVAPGHPLEKGYLPVPRGAPDGEACVEPHDGPEA----LNGGP-GLGRLVGGAPEGPQTLLAAEEETQARLLPAGGGEDVPCPARP--PRTALSPRRFVVLLIFSLYSLVNAFQWIQYSSISNVFEDFYQVSPLHINWLSMVYMVAYVPLIFPATWLLDTRGLRLTALLGSGLNCLGAWVKCGSVKQHLFWVTMLGQILCSVAQVFILGLPSPVASVWFGPKEVSTACATAVLGNQLGTAVGFLLPPVLVPKTQNNNTGLLADTQNSTDLLDDTQNSTDLLADNISIMFYGTAFVSTFLFFLTVIAFKERPLLPPSQAQAVLRDSPPAEYSYKTSICNLFRNVPFVLLLISYGIMTGAFYSVSTLLNQIILTHYEGEEVNAGRIGLTLVVAGMVGSILCGLWLDYTKTYKQTTLIVYILSFVGMVIFTFTLKLGYIIVVFFTGGILGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNTAAQIFGILFTLAQGKLTTDYN-PEAGNIFLCAWMFVGIILTALIKSDLRRHNINTG-LTNSDVKAVPVDSLIDQKPK-AMVSVQ---LESSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RXV4-1", "uniprot_id": "FLVC1_MOUSE", "id": "B2RXV4-1", "name": "Choline/ethanolamine transporter FLVCR1", "aln": "MARPDDEVGPAVAPGHPLGKGYLPVPKGAPDGEARLVPQNGPEA----LNGGP-GLGPLIAGAQGGPQALIAAEEETQARLLPAGDGEDVPCPACP--PRTALSPRRFVVLLIFSLYSLVNAFQWIQYSSISNVFEDFYEVSPLHINWLSMVYMVAYVPLIFPATWLLDTRGLRLTALLGSGLNCLGAWVKCGSVQRHLFWVTMLGQILCSVAQVFILGLPSPVASVWFGPKEVSTACATAVLGNQLGTAVGFLLPPVLVPALG---------TQNSTGLLAHTQNNTDLLAHNINTMFYGTAFISTFLFFLTIIAFKEKPPLPPSQAQAVLRDSPPEEYSYKSSIWNLCRNIPFVLLLVSYGIMTGAFYSISTLLNQIILTYYVGEEVNAGRIGLTLVVAGMVGSILCGLWLDYTKTYKQTTLIVYVLSFIGMLIFTFTLNLGYIIVVFFTGGILGFFMTGYLPLGFEFAVEITYPESEGMSSGLLNTAAQILGIFFTLAQGKITTDYNSPEAGNIFLCAWMFVGIILTALIKSDLRRHNINTG-LTNIDVKAVPVDSRVDPKPK-VMVSIQ---SESSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5Y0-1", "uniprot_id": "FLVC1_HUMAN", "id": "Q9Y5Y0-1", "name": "Choline/ethanolamine transporter FLVCR1", "aln": "MARPDDEEGAAVAPGHPLAKGYLPLPRGAPVGKESVELQNGPKAGTFPVNGAPRDSLAAASGVLGGPQTPLAPEEETQARLLPAGAGAETPGAESSPLPLTALSPRRFVVLLIFSLYSLVNAFQWIQYSIISNVFEGFYGVTLLHIDWLSMVYMLAYVPLIFPATWLLDTRGLRLTALLGSGLNCLGAWIKCGSVQQHLFWVTMLGQCLCSVAQVFILGLPSRIASVWFGPKEVSTACATAVLGNQLGTAVGFLLPPVLV---------------------PNTQNDTNLLACNISTMFYGTSAVATLLFILTAIAFKEKPRYPPSQAQAALQDSPPEEYSYKKSIRNLFKNIPFVLLLITYGIMTGAFYSVSTLLNQMILTYYEGEEVNAGRIGLTLVVAGMVGSILCGLWLDYTKTYKQTTLIVYILSFIGMVIFTFTLDLRYIIIVFVTGGVLGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNASAQIFGILFTLAQGKLTSDYG-PKAGNIFLCVWMFIGIILTALIKSDLRRHNINIG-ITNVDVKAIPADSPTDQEPKTVMLSKQ---SESAI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RGT2-1", "uniprot_id": "Q5RGT2_DANRE", "id": "Q5RGT2-1", "name": "Choline/ethanolamine transporter FLVCR1", "aln": "-----------MVAGEFLQEQHV-LPDSAPEGNTDEDS----------------GYKELSNGSVHITLDPKVLEQELPP---PDEKEAMLPAEQRSDALETRLYWRRFAVLAVFSLYSLVNAFQWIQYSIITNIFMDYYGVTSIAIDWLSVVYMVAYVPLIFPATWLLDKKGLRVTALLGAGLNALGAWVKCASVGPGLFWVTMTAQIICSVAQVFILGLPSRIASVWFGPREVSTACAFAVLGNQLGVAIGFLLPPVLVP---------------------NTADDKDLMGHNISIMFYGTAAVSTLLFLLTIFVIKDRPPLPPSKAQAVLSTGPAEDYSYKKSIINLFRNKPFILLLISYGIMTGSFYSVSTLLNQMIITHYKGEELNTGRIGLTLVVAGMFGSILCGIWLDRTKTYKLTTLIVYVLSFIGMVVFTFTLNV-HLLVIFFTAGVLGFFMTGYLPIGFEFGVEITYPESEGTSSGLLNAFAQVFGIIFTLIQGKLTTDYN-PLSGNIFLCAWILLGIVLTALIKSDLKRHDVNVGNINKAQAVSVPTELPSDKASSDVKMESSGLPHETTI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 305, "similar_positions": 127, "identity": "52.5%" }, { "cls_id": "homologset.agr.MGI:2444885", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7B9-1", "uniprot_id": "D4A7B9_RAT", "id": "D4A7B9-1", "name": "", "aln": "------------------MAFVFYCFLQVLVSWVTHAARPLCLSECTCSEESFGRSLQCMSMSLGKIPDNFPEGLKQVRIEKSPLFELPQGVFTNLNTL--EYLWLNFNNVTVIHLGALEDLPQLRELRLEGNRLRSVPWTAFRATPFLRVLDLKHNRIDALPELALQFLANLTYLDISSNRLTVVSKGVFLNWPAYQKRQQLGCGAEILSH---------MVLSLHNNPWLCDCRLTGLAQFVKSVGPPFILVNSYLICQGPVSKAGQLLHETELGDCMKP---IISTPSANVSIQVGKNVTLQCLAQASPSPTIEWKYPLSTWRKFDVLALP---------VAEGFILSQLVIPAAQLVDGTNYTCMASNSIGRSSLVITLYVQPAQ--------------------------------------------------------------------ATPGLHSLSTSSEG--SSYVDLRVVKQTVHGILLEWLTVTNLAGEQWFTLYIAS----------DEALEKKVVHIGPGIN-TYAVDDLLPATKY--------KACLGLRNQPPGQGQCVVFVTGKGSGE------LEGREHLLHVTVVLCAVLLALPVGAYVWATQGPCNCSEWCFRCFPLHRKTLRCPQAVPQCKDNSFTDPSAVCEDC---ESHRVVEEDEERE-KEGTS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PFC5-1", "uniprot_id": "LRIT2_MOUSE", "id": "Q6PFC5-1", "name": "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2", "aln": "------------------MAFVFYCFLQVLVSWVIHAVQPFCLPECTCSEESFGRSLQCMSMSLGKIPDNFPEELKQVRIENSPLFELSQGFFTNMSSL--EYLWLNFNNVTVIHLGALEDLPELRELRLEGNKLRSVPWTAFRATPLLRVLDLKHNRIDSVPELALQFLTNLIYLDISSNRLTVVSKGVFLNWPAYQKRQQLGCGAEFLSN---------MVLSLHNNPWLCDCRLRGLAQFVKSVGPPFILVNSYLVCQGPVSKAGQLLHETELGVCMKP---TISTPSVNVTIQVGKNVTLQCFAQASPSPTIAWKYPLSTWREFDVLASP---------IAEGIILSQLVIPAAQLVDGGNYTCMAFNSIGRSSLVILLYVQPAQ--------------------------------------------------------------------AMPGLHFLSTSSEV--SAYVDLRVVKQTVHGILLQWLTVTNLAEEQWFTLYITS----------DEALRKKVVHIGPGIN-TYAVDDLLPATKY--------KACLSLRNQPPSQGQCVVFVTGKDSGG------LEGREHLLHVTVVLCAVLLALPVGAYVWVSQGPYNFSEWCWRRCPLHRKTLRCPQAVPQCKDNSFKDPSGVYEDG---ESHRVMEEDEEVE-KEGIS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NDA9-1", "uniprot_id": "LRIT2_HUMAN", "id": "A6NDA9-1", "name": "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2", "aln": "------------------MASVFHYFLLVLVFLDTHAAQPFCLPGCTCSEESFGRTLQCTSVSLGKIPGNLSEEFKQVRIENSPLFEMPQGSFINMSTL--EYLWLNFNNISVIHLGALEHLPELRELRLEGNKLCSVPWTAFRATPLLRVLDLKRNKIDALPELALQFLVSLTYLDLSSNRLTVVSKSVFLNWPAYQKCRQPDCGAEILSS---------LVVALHDNPWVCDCRLRGLVQFVKSITLPVILVNSYLICQGPLSKAGQLFHETELSACMKP---QISTPSANITIRAGQNVTLRCLAQASPSPSIAWTYPLSMWREFDVLTSS---------TGEDTALSELAIPAAHLVDSGNYTCMASNSIGKSNLVISLHVQPAQ--------------------------------------------------------------------ALHAPDSLSIPSEG--NAYIDLRVVKQTVHGILLEWLAVADTSKEEWFTLYIAS----------DEAFRKEVVHIGPGIN-TYAVDDLLPGTKY--------EACLSLEGQPPHQGQCVAFVTGRDAGG------LEAREHLLHVTVVLCVVLLAVPVGAYAWAAQGPCSCSKWVLRGCLHRRKAPSCTPAAPQSKDGSFREHPAVCDDG---EGHIDTEGDKEKGGTEDNS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q504C1-1", "uniprot_id": "LRIT2_DANRE", "id": "Q504C1-1", "name": "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2", "aln": "------------------MDVCVLFHLIVFCILISHISS-ECFPGCSCGTDRHGRSLTCMETALTGIPDGLPEDLTKIRIEKSQLSELPEAVFSHVKAL--KHLWLNFNDIAIINIKSLEGLANLTELRLQGNKLRSVPWTAFEETPNLKILDLKHNRIDALPEHALKFLPGLTYLDLSSNQLSVISKDVFLNWPLYHSENK--HEKPSASN---------VVLALHDNPWLCDCRLGGFIEFIKSLTPPFILMNSYLTCSSPELKAGRFFHEVDLKTCVKP---VVSAPVITITAPLGGNVTLTCSASARPEAVIRWIYALKMLRGFRDILSH---------VDEDTISSQLVIPSLHSADRGLYTCIANNFLGNSSVIISVDVKSPE--------------------------------------------------------------------GSSSHPSGPSAAIGEENVYIDIRIAKQTVYGITIEWRAVTENPAETWFTIHFGR----------YDAVKKEQIYIGPGIN-TYSVTDLLPATKY--------EICVTLKNQAPRIGQCIVFVTGSDFNE------MEQREKLIHIVVIVLAMVLAVPAGMYACTTDAKFNCFERCAELWRNRRHAELSNPTGD--RQGTFDSLQAASDEGLYKESNKDKKARRRSAEKIHKTKNDRRPTAELY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHL5-1", "uniprot_id": "A0A0B4KHL5_DROME", "id": "A0A0B4KHL5-1", "name": "", "aln": "----MHRSMDRRRSRTPRTLPVCWILLCLVAWTVADDWSLSCASNCTCKWTNGKKSAICSSLQLTTIPNTLSTELQVLVLNDNHIPYLNREEFSTLGLLNLQRIYLKKSEVQYIHKESFRNLKILVEIDLSDNKLEMLDKDTFMGNDRLRILYLNGNPLKRLAAYQFPILPHLRTLDMHDCLISYIDPMSLANLNLLEFLNLKNNLLESLSEYVFQHMANLKTLSLEENPWQCNCKLRKFRGWYVNSR----LSSVSLVCKGPPAQKDRTWDSVDDELFGCPPRVEIFNNEEVQNIDIGSNTTFSCLVYGDPLPEVAWELNGKILDNDNVLFESES-------IASDKLWSNLTVFNVTSLDAGTYACTGSNSIGSMTQNISIYLSEIVQHVLEKTPETFWYFGLIMGIFGTVFLLISISFVVCLCKRTTRQHRHANKAGVKSSVSFNDQEKKLLDSSVTTTTNDRGDSYGIDNQPTSIGMNKGDSAGMGFNQIEIHAVESHRHGSMLVQQQPQ-QQQVAGGGGMRQQLMQVKDSTCGMMSVPTSMAGHAHSHPAQISEEFPLNVGVFPPPPEFCSNIVPNPAFGGNIFIRVSVTQDMLDGADLNMYPDLLNIPKRMQDVQESGAGAVAVPEGQFATLPRHTARRGILKKDTSLQQQQQQHQQQHQHQQQQQQQQIQQQQHQQLQQQHQPSGLYTHDEIVTYNLEASGYDPHQSGYHSNAMELPPPPPPPAVTAVVQCHHPSPNNCASCINNAPPPPSACQSPPVEVTPMRP---LDSSAYPKYDNMGRRITASGGLGGSNLSLHDEERYENETLFGQAESQ--------TKGMPEQSQDLHQPQEVTQGQDKGGGPGEFVSLXYYGTQV--------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWI6-1", "uniprot_id": "Q9VWI6_DROME", "id": "Q9VWI6-1", "name": "", "aln": "MMGNRTERSGRRLGMILLLLGVLVVLMALPPPTAGTTDWMQSCGTCHCQWNSGKKSADCKNKALTKIPQDMSNEMQVLDFAHNQIPELRREEFLLAGLPNVHKIFLRNCTIQEVHREAFKGLHILIELDLSGNRIRELHPGTFAGLEKLRNVIINNNEIEVLPNHLFVNLSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNRLSHLHKETFKDLQKLMHLSLQGNAWNCSCELQDFRDFAISKR----LYTPPTDCQEPPQLRGKLWSEVPSENFACRP--RILGSVRSFIEANHDNISLPCRIVGSPRPNVTWVYNKRPLQQYDPRVRVLTSVEQMPEQPSQVLTSELRIVGVRASDKGAYTCVADNRGGRAEAEFQLLVSGDYAGAVSASDG--------MGMGAIGAPTIDPQTNMFLIICLIITTLLLLLLVAVLTLFWYCRRIKTYQKDTTMMSGDGLISSKMDKTHNGSMLEGSVIMEMQKSLLNEVNPVEKPPRRTDIESVDGGDDVLEIKKTLLDDTVYVANHSRDEEAVSVAMSDTTTTPRSRHTYVDDAYANSLPPDLLAFPARVPPTSPSMQS--SQSNIPDQVIYGIRSPPSLTSPVYTHMTPHGIYGTKTMTAPHNGFMTLQHPKSRNLALIATTNSSRQHQHHHQLQQQQQHHHHHQQQQQQQQQQQHPLATTSPFLPAPVVYSPATG---VVMKQGYMTIPRKPRAPSWAPSTSGAAGHGSIQLSEFQSPTSPNPSETGTATTAELQAEPVYDNLGLRTTAGGNSTLNLTKIAGSQGGAGQQYSMRDRPLPATPSLTSVSSATNASKIYEPIHELIQQQQQLQQQQQQQQQRLGSMDTEPLYGVRQQGITILPGSSISGAGLGHAAYLSPGSGAAVSPSHASSSGDSPKAAKIPPRPPPKPKKKMSVTTTRSGQGSTSQLFDDEGEDGTEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * * :: * . * ** :. : : : .. : : . * . ::*. : :: ::. * * *: *..*:: : :* *: : :: * :. :. : * * ::: . : :. : . ::*. *.* *.*.* : : . * . *. * .: .. : * :: * . * . : * . *:* : * *:* . * * : : :. : . . : : . . . . .. : : :* :. .* *. . : : : . : . .: . : : .. ", "identical_positions": 41, "similar_positions": 113, "identity": "4.32%" }, { "cls_id": "homologset.agr.MGI:2444888", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M2Z5-1", "uniprot_id": "NCMAP_RAT", "id": "F1M2Z5-1", "name": "Noncompact myelin-associated protein", "aln": "---MTTATTLGD-AVFSLNMT-RGEDILYKSSGAIVAAIVVVVVIIVTLVLILLKMYNRRMRTRRELEPKSPKPPVPPALDPNSNGSQQPAAVTSDPADVPVETR---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JS0-1", "uniprot_id": "NCMAP_MOUSE", "id": "Q99JS0-1", "name": "Noncompact myelin-associated protein", "aln": "---MTTATTLGD-AVFSLNMT-RGEDALYKSSGAIVAAIVVVVIIIVTLVLILLKMYNRRMRTRRELEPKSPKPPVPPALDPSSNGSQQPATVTFDPANVHVETR---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T1S8-1", "uniprot_id": "NCMAP_HUMAN", "id": "Q5T1S8-1", "name": "Noncompact myelin-associated protein", "aln": "---MTTATPLGDTTFFSLNMTTRGEDFLYKSSGAIVAAVVVVVIIIFTVVLILLKMYNRKMRTRRELEPKGPKPTAPSAVGPNSNGSQHPATVTFSPVDVQVETR---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WDD4-1", "uniprot_id": "X1WDD4_DANRE", "id": "X1WDD4-1", "name": "", "aln": "MQRASTVSVTQATTQNTTAFTKSREQILTQSSGAMIAVIVIGIIIILTFLLIVLKTYNRRTHAKRMLSGGSSKPRKKVSSTTTNTNLAMSNVGTSSASGSFIQSNGSSENGFRIPRVDLGNIDHSNGEHFSTNSGSTIVTIHDMPSVDNT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.: : : :* *: * :****::*.:*: ::**.*.:**:** ***: :::* *. ..** : ..... . . * .. . :::. ", "identical_positions": 25, "similar_positions": 41, "identity": "16.67%" }, { "cls_id": "homologset.agr.MGI:2444889", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1B1A0-1", "uniprot_id": "LMBL4_MOUSE", "id": "B1B1A0-1", "name": "Lethal(3)malignant brain tumor-like protein 4", "aln": "MRQPNRKRKLSLESTERMNQDRCTGQTEEEKKPGEVTTPSKRESSVTTAETWSWEQYLREGNAVAAPVELFSKDQSFPEHENGFQVGMRLEGIDARRPSVFCVLSVAEVCGYRLRLHFDGYLSCYDFWTNAGSPDIHPVGWCQKTKHELHIPRDYRKDKFVWMDYLKACRLQNAPKKLFRNRSSNGPVPREFQVGMKLEAVDRRNPCLMCVATIADIVEDRVRVHFDSLDDSFDYWCDVNSPYIQPVGWCQENGRTLVAPQGYPHPDKFSWTDYLRASQSKAVPAKAFGMRTPHGFLPNMKLEAVDKRNPQLIRVATIADVDDYRVKIHFDGWDHKYDYWVDADSQDIHPIGWCDVTGHPLEVPYGSKHVKILPGQPACPTPGCRGIGHIRGPRYAGHHSAFGCPYSDVNLKREAALQDRLREQTQANLELDPSHSKSENPCNLNVNGKCENANSQCRLVQQAKCLKIKGKEDIDLDNLFRVLVFHPRRLEYSAAQVQQMLHQPLSMTSTSAHPFRDIPLSREQHCKLLPGVADIQASQVARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQADIVKVMRIKLGPALKIYNSILMFRNSQDVT-EDASS-QEDKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M8A7-1", "uniprot_id": "F1M8A7_RAT", "id": "F1M8A7-1", "name": "", "aln": "MRQPNRKRKLSMASTEHMNQDGRMGQTEEETKPGDGATPSGRESSVTTQETWSWEQYLREGNAVAAPVELFSKDQSFPEHENGFQVGMRLEGIDARRPSVFCVLSVAEVCGYRLRLHFDGYLSCYDFWTNAGSPDIHPVGWCQKTKHELHIPRDYRKDKFVWMDYLKACRLQNAPKKLFRNRSSNGPVPKEFQVGMKVEAVDRRNPCLMCVATVADIVEDRVRVHSDSWDDSFDYWCDVSSPCIQPVGWCQENGRNLVTPPGYPGPDKFSWADYLQATQAKAVPAKAFNTRAPHGFLPNLKLEAVDKRNPRLIRVATVTDVDDYRVKIHFDGWDHKYDYWMDADSQDIHPIGWCDVTGHPLEVPYGSEHVKILPGQPSCPTPGCRGIGHIRGPRYAGHHSAFGCPYSDVNLKREAALQDRLREQTQANLEFDPSHSKSENLCNLNFNGKCEEVDSECRLVQQAKCLKIKGREDTDLDNLFR---------EYSASQVQQMLHQPLSMTSMSAHPFRDLPLGREQHCKLLPGVADIQASEVARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQADIVKVMRIKLGPALKIYNSILMFRNSQDVT-EDTASGQEARR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NA19-1", "uniprot_id": "LMBL4_HUMAN", "id": "Q8NA19-1", "name": "Lethal(3)malignant brain tumor-like protein 4", "aln": "MKQPNRKRKLNMDSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWSWEWYLKEQKAVAAPVELFSKDQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDGYLSCYDFWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFRNRSPNGPMSKEFQVGMKLEAVDRKNPSLVCVATIADIVEDRLLVHFDNWDDSYDYWCDVNSPYVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLPHGFLPNMKLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPLEVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDRLREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKCLKIKGKEDIDLDNLFRVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALKIYNSILMFRHSQELPEEDIASGQEVRG", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:********.: *.*:::** *:***.** : :** : .*.:: :**** **:* :***********************:********.*:*********************************************:*********:.***************:*************.***:.:*******:*****:**.*:****:*******: ** *. ***:******.** :***********.*::* *** *::***::**.*:*::*****.* * *******:***.******:******:.**** ***:************::*** ****************** ::.:******. *****************:************:***:**:*:************ *.*****:. *.**.*** *:.:*: *************:** ******* ***. *.**:***.:**:: *******:**.**************:**:*****************************************:******:*****************:**::. ** :* ** : ", "identical_positions": 475, "similar_positions": 99, "identity": "76.24%" }, { "cls_id": "homologset.agr.MGI:2444891", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BUZ1-1", "uniprot_id": "ABRA_MOUSE", "id": "Q8BUZ1-1", "name": "Actin-binding Rho-activating protein", "aln": "MAPGEREREAGPAKSALRKVRTATLVINLARGWQQWANENSTKQAQEPAGWLPGATHDLPNAPKEAGP------YQHAPKTLSPKPDRDGEGQHSEEATEVSHIKRKEVTRTVVSKAYERGGDVNYLSHRYENDGGVSEAIQPENDIDRILLSHDSPTRRRKCTNLVSELTKGWKVMEQEEPTWKSDSVDTEDSGYGGDMEERPEQDAAPVAPARIKRPLLSQANRYSETLNCKAHRKYSQVDNLKGRWQQWADEHVQSQKLNPFSDEFDYDLAMSTRLHKGDEGYGRPKEGS----KTAERAKRAEEHIYREIMELCFVIRTMARHRRDGKIQVTFGELFDRYVRISDKVVGILMRARKHGLVHFEGEMLWQGRDDHVVITLLE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K4K7-1", "uniprot_id": "ABRA_RAT", "id": "Q8K4K7-1", "name": "Actin-binding Rho-activating protein", "aln": "MAPGETEREAGPAKSALQKVRRATLVINLARGWQQWANENSTRQAQEPAGWLPGATQDLPHTPKEPGP------RQHAPKPPSPKPDGDREGRGSEEATEVSHIKRKEVTRTVVSKAYERGGDVNYLSHRYEHDGGVSEAVQPDNDIDRILLSHDSPTRRRKCTNLVSELTKGWKVMEQEEPKWKSDSIDTEDSGYGGDMEERPEQDVAQVAAARIKRPLHSQANRYSETLNCKAHRKYSQVDNLKGRWQQWADEHIQSQKLNPFSDEFDYDLAMSTRLHKGDEGYGRPKEGS----KTAERAKRAEEHIYREIMELCFVIRTMARHRRDGKIQVTFGELFDRYVRISDKVVGILMRARKHGLVHFEGEMLWQGKDDHVVITLLE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N0Z2-1", "uniprot_id": "ABRA_HUMAN", "id": "Q8N0Z2-1", "name": "Actin-binding Rho-activating protein", "aln": "MAPGEKESGEGPAKSALRKIRTATLVISLARGWQQWANENSIRQAQEPTGWLPGGTQDSPQAPKPITPPTSHQKAQSAPKSPPRLPEGHGDGQSSEKAPEVSHIKKKEVSKTVVSKTYERGGDVSHLSHRYERDAGVLEPGQPENDIDRILHSHGSPTRRRKCANLVSELTKGWRVMEQEEPTWRSDSVDTEDSGYGGEAEERPEQDGVQVAVVRIKRPLPSQVNRFTEKLNCKAQQKYSPVGNLKGRWQQWADEHIQSQKLNPFSEEFDYELAMSTRLHKGDEGYGRPKEGT----KTAERAKRAEEHIYREMMDMCFIICTMARHRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLVDFEGEMLWQGRDDHVVITLLK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UW36-1", "uniprot_id": "A0A8N7UW36_DANRE", "id": "A0A8N7UW36-1", "name": "Actin-binding Rho-activating protein", "aln": "MSTAGVQQNR-PFSRAVRKIKVASTVNSLAKSWQSWANKHSDKQDTIPSGWMP---DTIIEDAKE---------KQKEKNEMKLLVTPRVVSVVGEEATDD-QIKTGIVTKAITPKCNEFGKDLVSVIKEKINTN------QLTTEDTKNFLGNESPTRRRYCGGKAGTFVKAIGRKEGKSMGSRSSSLDADDSGLG---EEASLSDNSDLNENEPKK----HVNRH--------KIKVTTMGDLRSRWQRFAEDHMEGQKLNPFSEEFDYDHAMATRLHKGDAGYGRPKEGS----KTAQRADRAQKHIYREMEEMCFIIRDMGQQDKQGQIWVTFGRLFDRYVKISDKVVGILLRCRKHKMVDFEGEMLWKGQDDDVIITLLV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46052-1", "uniprot_id": "O46052_DROME", "id": "O46052-1", "name": "Costars domain-containing protein", "aln": "-------MTDVSHELGALRFVVDSPLSSKVAMFNNQATQHKQSQLLNPFSQDGRAASPKPTFSKDQYG-------KPLAGSLTEMRGQKANIHVMKEMLELCQIINS-EGYDVKDEPTMRVIPFGELFNIYNYISDKVVGILLRARKHKLVDFEGEMLYQRRDDDVPVFLLKPIKEIRSEMEA-KIEDIKRAASPAPPQSTSVLMDRSAHEQKLKSRTPSPAVGKSAKSKSASPAPKAPVPVPAPAAEVTPVAGPTTSAEPAPVAESTMAAVPAPSTEPTPATAPASSTVEIEPAKPEVTEQAPVAVIVTEAPSTEETTPTTSEPQAEEAPAAVAPAGPADDLPTIVIEATAEFVRTVSVEQLAPSPGTASESSPDQSQSQPESTPA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZW6-1", "uniprot_id": "Q9VZW6_DROME", "id": "Q9VZW6-1", "name": "Costars domain-containing protein", "aln": "-------MAESQESP------QDSSVSSRITLFNQQAEQHKNWMMINPFAHYNVNEMPKRTFPEEEYG-------RAPTGSLSEQRSLQANVRALEEILQLCDLIQK-SGRDDPID-GRKVLAFGQLFETYNNISDKLLATLLGARKYGFVDFSGETLFQGRDDTEPVRLLRPFEELQAEIIS-KVADLRCDFTEKPEEPTLLRED-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . ::. * ::. * . .: : :: : .: . . : . . . : : : . : : .: : . ", "identical_positions": 2, "similar_positions": 35, "identity": "0.52%" }, { "cls_id": "homologset.agr.MGI:2444896", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYM3-1", "uniprot_id": "D3ZYM3_RAT", "id": "D3ZYM3-1", "name": "", "aln": "MVDAAGFESIAQCPQELHQMMAAAADGLGSIALDTTQLNMSVTDPTAWATAMNNLGMVPVG-----------------------LPGQQLVSDSICVPG-----------------FDPGLNMMTGITPINPMIPGLGLVPP----------------------------------------------------PPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEHEAALLAEKLKDDSKFSEAITVLLSWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESEADTEDCAGDMADPGLHSAALAAQAYALKEENDSLRWQLDAYRNEVELLKQ---EKEQLFRTEENLTKDQQLQFLQQTMQG-----------------------MQQQLLAIQEELNNKKS----------------------------------ELEQAKEEQSHTQALLKVLQEQLKGTKDLVETNGHSHEDANEINVLTVALVNQDRENNTEKRSQG-LKSEK----------------EALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISASEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHR2-1", "uniprot_id": "ENOX1_MOUSE", "id": "Q8BHR2-1", "name": "Ecto-NOX disulfide-thiol exchanger 1", "aln": "MVDAAGFESVAQCPRELHQMMAAAADGLGSIALDTTQLNMSVTDPTAWATAMNNLGMVPVG-----------------------LPGQQLVSDSICVPG-----------------FDPGLNMMTGITPINPMIPGLGLVPP----------------------------------------------------PPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEHEAALLADKLKDDSKFSEAITVLLSWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDES-------------------ALAAQAYALKEENDSLRWQLDAYRNEVELLKQ---EKEQLFRTEENLTKDQQLQFLQQTMQG-----------------------MQQQLLAIQEELNNKKS----------------------------------ELEQAKEEQSHTQALLKVLQEQLKGTKDLVETNGHSHEDANEINVLTVALVNQDRENNTEKRSQG-LKSEK----------------EALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TC92-1", "uniprot_id": "ENOX1_HUMAN", "id": "Q8TC92-1", "name": "Ecto-NOX disulfide-thiol exchanger 1", "aln": "MVDAGGVENITQLPQELPQMMAAAADGLGSIAIDTTQLNMSVTDPTAWATAMNNLGMVPVG-----------------------LPGQQLVSDSICVPG-----------------FDPSLNMMTGITPINPMIPGLGLVPP----------------------------------------------------PPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEHEAALLAEKLKDDSKFSEAITVLLSWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDES-------------------ALAAQAYALKEENDSLRWQLDAYRNEVELLKQ---EKEQLFRTEENLTKDQQLQFLQQTMQG-----------------------MQQQLLTIQEELNNKKS----------------------------------ELEQAKEEQSHTQALLKVLQEQLKGTKELVETNGHSHEDSNEINVLTVALVNQDRENNIEKRSQG-LKSEK----------------EALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WCA2-1", "uniprot_id": "X1WCA2_DANRE", "id": "X1WCA2-1", "name": "", "aln": "--------------------MASAADGIGSLGTEQSHINVPVADPGAWATAMNNLGIVPMG-----------------------LTGQQLVSDSICIQG-----------------FDPNIGIIT---PINPMMAGISLVPPH---------------------------------------------------PVAAELPVIKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIKEVFDQCGEIIAIRKSKKNFCHIRFIEEFMVDKALYLSGYRMRIGSSTDKKDSGRIHVDFAQARDDLYEWECKQRLLAREERHRRKIHEERLRPPSPPPIMHYSEHEATLLAEKLKDDNKFSEATAVLFTWIDRGEVNRRSANHFYSMIQSANSHVRRLMSEKAQHEEEMELAKEHFKNSLLAILTQFEQITAVFTAATRQKAWDHFSKAQRKNIDIWRKQCEELRNAHSEEIMGIRREEEMEMSDEDSDENPCKKIRLEDS-------------------VLSAQSCALREENDSLRWQLDAYRNEVELLKK---EQGKMYRTEEDHTHEQQLHFLQQTMQN-----------------------MQQQLLRLQEELKGKEL----------------------------------ELEQARDEQRYLEGEVISLREKLLNAMESVDMTNHNS-ECHEKAVNGTAALYHHREKNNETVIWGPLRSEK----------------EALLLGIISTFLHVHPFGANIEYLWSYIQRLDTKISASELERLMVRLPNMFKQEFSGVGATLEKRWKFCGFEALKSA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU18-1", "uniprot_id": "Q9VU18_DROME", "id": "Q9VU18-1", "name": "RRM domain-containing protein", "aln": "MLPLFGTMPNGVSLPNHPNFLNQLAAAISTAASSTSVVGNPSSPPKQIQNKMAKQQQQPQGSAPMDLENENEHSADVSSSTMHKEPKLQATSNSLTLPDSTQLYLNGLVHTPPGYLYFPATQAGGATAPGNPSSAAGGSTPAASANSTANAQMLMDPTAMMAAAMQQMQQMHYAAAAAAGMTTETGAGLEATLNADGVTPAGLKEVIKTKNCILFPPNPNAPPPTIRERPPGCRTVFVGGLPENITEEVIREIFESCGEITTLRMSKKNFCHIRYRQEGAIDRAIYLSGYRLRISALNEPPNFGRLHVDYAQARDDQYDYECRQRQHQREQRHRERMSMDRMRSQSPPPIPHYTDHEATTVAEHLRTNETFVKAIQTITAWLERGDCTKRNANVFYSMIQSTHAHVRRLHADKLQLEEDLKKARDSYRNQMGTMSTQFTQIEKVFNAASHKKVWDHFTKAQRKNIDQWKKLATELR------TVQITDDDEMEISDDERDYDRRGHSAKRIR----------------------YDSDGLKDENDSLRCQLEAIRHEMTLERSDYVQREKQIKVLQETIRNMQTQLLQTKLREQKDNKTIEQLERNLKDAGIKQLLLKTKIKETVDKLRDKEANSAGASNASNASNLDYSSGDSCSREGTEIIRPQAEPEIIDIDKVDDDVRIIEHQSGVVEIHEIEDDEKQEPAKDSTKSKANESIMENVSKSNHEETINKSSKEQIPTVAAEEVTFKSLVLSEAKIIALASAYLVLHPYGVEIANIASYLSEMLRNNAAPSNHDDLANILGKYTNLFK----PEKEKWRFCGFSEPTESQTESK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .:.: . . : :. . : * . * : * * . * .*:*: : . : * * ** .. . .*. . . . :**:*: *.* *** *** ***: *******:********** ***:*:*:*:.**:* ::* *********: :* :*:*:******:*:.: .: : **:***:****** *::**:** **:***.:: :*:*. ***.* **::***: :*::*: :..* :* .: :*::**: .:*.** ****:**:::***** :* *:::: *:: ::* : : *** ** **.*::::*.****:******** *:* . *** : * ::***:**:: . : :: .*::****** **:* *:*: * :. :: : :. :: :: * ::** .:: :: :: ::*..*: * * :: : : :. : : : :. . : : : :.* * :.: ** ::.: *::* :**:*.:* : **:..: : :* . . : .: :.: *. . :::*::*.*. . : ", "identical_positions": 199, "similar_positions": 209, "identity": "23.8%" }, { "cls_id": "homologset.agr.MGI:2444898", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XDG1-1", "uniprot_id": "A0A8J8XDG1_RAT", "id": "A0A8J8XDG1-1", "name": "E3 ubiquitin-protein ligase CHFR", "aln": "MEPHGEDEQPPPREPWGRLLRLGAEEDEPQILLWKREWTIGRRRGCDLSFPSNKLVSGDHCKLRVDEKSGEVTLEDTSTNGTVINKLRVVKKQTYPLQSGDIIYLVYRKNEPEHNVAYLYESLNGKQSLTQESLEANKENMFHVTKESSGP--GQGDDPQVPLLSPMAQTCLEEPQPSTSTSDLLPTASTSSTEPELTSAGQKHSSSSGPGTISISPKECSSLVANGELSSLSSVFQD-NEASFSLLKTEDTEELEPAKKKMKGDGELDLNLQLSVADQRGIAQTSSEDVKDASVKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLLQHPDKSRSEEDVRSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYIVCRQCPEYRRQAVQSLPCPVPESELGATQALGGEAPSTSASLTTAAPGYTCPLQGSHAICTCCFQPMPDRRAEHEQDSRIAPQQCAVCLQPFCHLYWGCTRTGCFGCLAPFCELNLGDKCLDGVLNNNNYESDILKNYLTTRGLTWKNMLTESLLALQRGVFILSDYRITGNTVLCYCCGLRSFRELTYQYRQNIPASELPVTVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q810L3-1", "uniprot_id": "CHFR_MOUSE", "id": "Q810L3-1", "name": "E3 ubiquitin-protein ligase CHFR", "aln": "MELHGEEQPPPPQEPWGRLLRLGAEEDEPQILLWKREWTIGRRRGCDLSFPSNKLVSGDHCKLTVDEISGEVTLEDTSTNGTVINKLQVVKKQTYPLQSGDIIYLVYRKNEPEHNVAYLYESLSGKQSLTQDSLEANKENMFHVTKDCSGP--GQGDDPQVPLLSPMAQTCLEEPQPSTSTSDLLPTASTSSTEPELTSAGQKHSSSSGPGNTSISPKGRSSLVANGELSSLSPVFQD-KEASFSLLESKDHEELEPAKKKMKGDGELDTNLQLLVSGQRGNAQTSSEDVKDASVKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLIQHPDKSRSEEDVRSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYIVCRQCPEYRRQAVQSLPCPVPESELGATLALGGEAPSTSASLPTAAPDYMCPLQGSHAICTCCFQPMPDRRAEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCFGCLAPFCELNLGDKCLDGVLNNNNYESDILKNYLATRGLTWKSVLTESLLALQRGVFMLSDYRITGNTVLCYCCGLRSFRELTYQYRQNIPASELPVTVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96EP1-1", "uniprot_id": "CHFR_HUMAN", "id": "Q96EP1-1", "name": "E3 ubiquitin-protein ligase CHFR", "aln": "MERPEEGKQSPPPQPWGRLLRLGAEEGEPHVLLRKREWTIGRRRGCDLSFPSNKLVSGDHCRIVVDEKSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEPEHNVAYLYESLSEKQGMTQESFEANKENVFHGTKDTSGAGAGRGADPRVPPSSPATQVCFEEPQPSTSTSDLFPTASASSTEP--SPAGRERSSSCGSGGGGISPKGSGPSVASDEVSSFASALPDRKTASFSSLEPQDQEDLEPVKKKMRGDGDLDLNGQLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYVVCRQCPEYRRQAAQPPHCPAPEGEPGAPQALG-DAPSTSVSLTTAVQDYVCPLQGSHALCTCCFQPMPDRRAEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTVLCYCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WW08-1", "uniprot_id": "CHFR_DANRE", "id": "A5WW08-1", "name": "E3 ubiquitin-protein ligase CHFR", "aln": "MTNQDSD------QAWGKLVKVDASPG-SEIVLINSECTVGRKKDCDLSFPANKLVSGNHCKITHDQNSGKVWLEDMSTNGTVINMSKVVKKQTHLLQNGDVIYFVYRKNEPEQNIAYVYQSITPQESASHDVEDAGREEDSDLTETESEP-----APVEPVIVKPLPQSGHEDPQPSTSSSSLHFYNMP--------------LSTCSDVSARKNPVSSSAVCKGDSTSSGSPAQTRLKWTCWTDGEPE--EEMQRKRRKTDRD-DPGFGSAHSDASADIPLRGASGKEKTEGATTDKMEESLTCIICQDLLYDCISVQPCMHTFCAACYSGWMERSSFCPTCRCPVERIRKNHILNNLVEAYLLQHPEKCRTEDDLRSMDARNKITQDMLQPKVERSFSDEEASSDYLFELSDNDSDISDMSQPYMMCRQCPGYRKELSSALWICESAQSESLAKTAGDGPSTSSDSTTAAPQEFRCPPQASHLICTCCLQPMPDRRFEHLP-PQVSPQHCLVCQKPFCHVYWGCPRIGCHGCLARFSELNLNDKCLDGVFNGNQYESEVLQNYLSCRGMSWRHLLQDSLQALQQGLYHLSDYRITANSFLCYCCGLRTFRELAYKYRERIPPSELPDAVTNRPNCYWGRNCRTQVKAHHALKFNHICEQTRFKN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . :.**:*:::.*. . ..::* : * *:**::.******:******:**:: *: **:* *** **.***** :****** **.**:**:********:*:**:*:*:. ::. ::: :*.:*: . *: * . . .* .* *:******:*.* . *:.. .* .. ... ** :.. : :.:: :.: *::: ::* * : . . : : . : . ..*****:**********:**:*:********************:*********** *************:***:*.*:*:*::*****************.*******.**: *:**** **: **:****::***** **:: .. . . . . : * ..::* * .:* : ** *.** :****:******* *: .:::**:* ** :****:****.* **.**** *.****.*******:*.*.***::*:***: **::*: :* :** ***:*:: *****:*.::.********:****:*:**:.**.**** :**.**:****************:*************", "identical_positions": 332, "similar_positions": 172, "identity": "49.78%" }, { "cls_id": "homologset.agr.MGI:2444899", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4G008-1", "uniprot_id": "K0930_RAT", "id": "Q4G008-1", "name": "Uncharacterized protein KIAA0930 homolog", "aln": "--------------------------MLRAIAEERGRLSLRREVCGLGCFKDDRIVFWTWMFSTYFMEKLAPRQ----DDMLFYVRRKRAYTGSESTADGRKAEAEPEVEVEVYRRDSKKLPGLGDPDIDWEESVCLNLILQKLDYMVTCAVCTRADGGDIHIHRKKSQQVFASPSKHPMDSKGEESKMSYPNIFFMIDSFEEVFSDMTVGEGEMVCVELVASDKTNMFQGVIFQGSIRYEALKKVYDNR-VSVAARMAQKMSFGFYKYNN-----MEFVRMKGPQGKGHAEMAVSR-----------------------------------------------------------------VSTGDTSPYGTE----------------------------------------------------------------DSSPASPMHERVTSFSTPP-------------------------------------------TPERNN-------RPAFFSPSLKRKVPRNR---------------------------IAEMKK-----------SHSAND---------------------SEEFFREDDGGADLHNATNLRSR--------------------------------------------------------------------------SLSGTGRSLVGS-------------------------------------------------------------------------------------------------------------------------------------------------------WLKLSRADGNFLLYAHLTYVTLPLHRILTDILEVRQKPILMT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UE31-1", "uniprot_id": "K0930_MOUSE", "id": "Q3UE31-1", "name": "Uncharacterized protein KIAA0930 homolog", "aln": "--------------------------MLRAIAEERGRLSLRREVCGLGCFKDDRIVFWTWMFSTYFMEKLAPRQ----DDMLFYVRRKRAYPGNEGTIDGRKAEAEPEVEVEVYRRDSKKLPGLGDPDIDWEESVCLNLILQKLDYMVTCAVCTRADGGDIHIHRKKSQQVFASPSKHPMDSKGEESKMSYPNIFFMIDSFEEVFSDMTVGEGEMVCVELVASDKTNTFQGVIFQGSIRYEALKKVYDNR-VSVAARMAQKMSFGFYKYNN-----MEFVRMKGPQGKGHAEMAVSR-----------------------------------------------------------------VSTGDTSPCGTE----------------------------------------------------------------DSSPASPMHERVTSFSTPP-------------------------------------------TPERNN-------RPAFFSPSLKRKVPRNR---------------------------IAEMKK-----------SHSAND---------------------SEEFFREDDSGADLHNATNLRSR--------------------------------------------------------------------------SLSGTGRSLVGS-------------------------------------------------------------------------------------------------------------------------------------------------------WLKLNRADGNFLLYAHLTYVTLPLHRILTDILEVRQKPILMT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ICG6-1", "uniprot_id": "K0930_HUMAN", "id": "Q6ICG6-1", "name": "Uncharacterized protein KIAA0930", "aln": "--------------------------MLRAIAEERGRLSLRREVCGLGCFKDDRIVFWTWMFSTYFMEKWAPRQ----DDMLFYVRRKLAYSGSESGADGRK-AAEPEVEVEVYRRDSKKLPGLGDPDIDWEESVCLNLILQKLDYMVTCAVCTRADGGDIHIHKKKSQQVFASPSKHPMDSKGEESKISYPNIFFMIDSFEEVFSDMTVGEGEMVCVELVASDKTNTFQGVIFQGSIRYEALKKVYDNR-VSVAARMAQKMSFGFYKYSN-----MEFVRMKGPQGKGHAEMAVSR-----------------------------------------------------------------VSTGDTSPCGTEE---------------------------------------------------------------DSSPASPMHERVTSFSTPP-------------------------------------------TPERNN-------RPAFFSPSLKRKVPRNR---------------------------IAEMKK-----------SHSAND---------------------SEEFFREDDGGADLHNATNLRSR--------------------------------------------------------------------------SLSGTGRSLVGS-------------------------------------------------------------------------------------------------------------------------------------------------------WLKLNRADGNFLLYAHLTYVTLPLHRILTDILEVRQKPILMT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IGU3-1", "uniprot_id": "A0A0R4IGU3_DANRE", "id": "A0A0R4IGU3-1", "name": "", "aln": "MSSARIMAALPGQSDDSAEPDESLQHMLKAIADERNRLNVRQDLSGLGCFKDDRIVFWTWMFSTYFMEKWAPRQ----DDMLFYVRRKLSYVS-EDNTEGKK------VEVEVYRRDSKKLPGLGDPDIDWEESVYLNLILQKLDYVVTCAVCTRSDAGDIHIHKKKSQQVFASPSKHPMDSKGEESKMSYPNIFFMIDNFEEVFSDMTVGEGEMVCVELVASDKSNTFQGVIFQGSIRYEALKKVYDNR-VSVAAKMAQRMSFGFYKYNN-----MEFVRMKGPQGKGHAEMAVSR-----------------------------------------------------------------VPTGDTSPCGTE-----------------------------------------------------------------EDQDSPLHERVTSFSTPP-------------------------------------------TPERN--------RPSFFSPSLRRKVPRNR---------------------------IAEMKK-----------SHSAND---------------------SEEFFREEED-EDMCNASNLRSR--------------------------------------------------------------------------SLSGTGRSLVGS-------------------------------------------------------------------------------------------------------------------------------------------------------WLKLNRKEEYFLLYSHLTYVTLPLHRITTDILEVRQKPILMT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAP1-1", "uniprot_id": "A1ZAP1_DROME", "id": "A1ZAP1-1", "name": "", "aln": "------MALASAAAALLKGSQTPLQQLLEDINFQRTKEMRQLLKDDGGFVVLQGTTYWTDLFVRHFLFQTEPVHSIDSDDLLFFVRKKHVKSSSRHMPKFET-------EVEVFRKDSRKLP-IGDPDVDWEETVYLNMVIHQFDYTLTLAICTRTSPKELQVLRRHSQRVYASPSRRKMDTKGEGEEITYPHICFMVDNFDEVFSDILVRDGEMVCVELVANDKDGAVQGVIFLGSIRYDALKKVYDARQSSLSSKVAQRMSFGLFSSGAGVQTRCEFVRMKGPQGKGHAEMAVTKPKGSGVETPTSEPGFCATDMWDEWEEENDDYCTYRHQRRLSDPSANLNNFSRYGWRTKNSNNQDMVGSGTSPSVGAKARSENEGLDSLASEVSEIEAGDLRDDQQRPAFSASAAKLHPNPNCETHKLATGDQEKLTQESPRESTSSAPAEVAVPAVTPPPLSAAVEVTVSGDVSVTGHSSTTGCNCFGGKKCKKRWASAKNTDTPEMSEVYCPSCEDPSNESPACLAKMPDKRPTRLKPKSSILSVESELLVGKRSSFRLPSEIKRKQQGGSITRSASLSAADRRTSLPVATKRIIPPRLRTAKAKDLEKDKEKEKDKNKENDKKSSNQKVNGSATNFLAKMSPKRLKAGKEKDKDKDGNKEKEKDKFKAMDAAKKKAVNNNNPKPDISKSEEYEIADDATSLNGSESEPVGAAKMVILSESDSKLMISVRGREELPVVDSPKTPPKRFEKCVSLPVEPESHLLQPDENNENEQSDITNVISPTELTPMLDVANGNGEANSATLPRTAKQAHVSKMLHLVPKRRTPDGTNIYYWCDVPKKAIKELDDGAYNPLWTSRGFTQSFHFWKENRRQQSTPLNAFLTYVTLPWWSIAKDLLDHRETPILTF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*. * :* : : . * . : .:** :* :*: : * : **:**:**:* . . . .. ****:*:**:*** :****:****:* **::::::** :* *:***:. :::: :::**:*:****:: **:*** .:::**:* **:*.*:*****: * :**********.** . .***** *****:******* * *:::::**:****::. . ******************:: * :* :.. *:: . :* . *.:.:.** *** . *: **: *:* :* :*:*: * ** * :::: ::.: * : .: :* **.*: . **: : * .* : * :.******* * .*:*: *:.*** ", "identical_positions": 170, "similar_positions": 125, "identity": "18.83%" }, { "cls_id": "homologset.agr.MGI:2444911", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BL03-1", "uniprot_id": "S2529_MOUSE", "id": "Q8BL03-1", "name": "Mitochondrial basic amino acids transporter", "aln": "------------------------------------------------------------------------------MALDFLAGCAGGVAGVIVGHPFDIVKVRLQVQSTEKPQYRGTLHCFQSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALG--------------------QDSPLN-QFLAGAAAGAIQCVICCPMELAKTRLQLQAVG-----PARTYKGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLTYDVMTR----AMGCEPGDRLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQADGLQGTPRYRGIVDCMRQSYQAEGWQVFTRGLASTLLRAFPVNAATFATVTVVLTYTRGE--------------------EAQVDSEAALG------------------------------------TSPTPAGSALAQPSSL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5HZE0-1", "uniprot_id": "S2529_RAT", "id": "Q5HZE0-1", "name": "Mitochondrial basic amino acids transporter", "aln": "------------------------------------------------------------------------------MALDFLAGCAGGVAGVIVGHPFDTVKVRLQVQNTEKPQYRGTLHCFQSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALG--------------------QDSPLN-QFLAGAAAGAIQCVICCPMELAKTRLQLQAAG-----PARAYKGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLTYDVLTR----AMGCEPGDRLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQADGLQGTPRYRGIVDCMRQSYQAEGWQVFTRGLASTLLRAFPVNAATFATVTVVLTYIRGE--------------------EDQVDSEAAPG------------------------------------ASTTPAGPALAQPSSL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N8R3-1", "uniprot_id": "S2529_HUMAN", "id": "Q8N8R3-1", "name": "Mitochondrial basic amino acids transporter", "aln": "------------------------------------------------------------------------------MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALG--------------------HDSPLN-QFLAGAAAGAIQCVICCPMELAKTRLQLQDAG-----PARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTR----ALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYARGE--------------------EAGPEGEAVP---------------------------------------AAPAGPALAQPSSL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TAT4-1", "uniprot_id": "A0AB32TAT4_DANRE", "id": "A0AB32TAT4-1", "name": "Mitochondrial basic amino acids transporter", "aln": "MLTGNARKQLMPRLLKKTPRPSVRVVTVRQCRSPRYLLCPRTPSICRRALITSIGVPTAQPDIPATPPDSSTTVHSDTSRHDHISSKLSGAAGVLVGHPFDTVKVRLQVQSVDKPLYRGTFHCFQSIIRQESVLGLYKGIGSPMMGLTFINAIVFGVQGNAMRRLG--------------------EDTPLN-QFLAGAAAGSIQCVICCPMELAKTRMQMQGTGEKKSSSRKVYKNSLDCLARIYQREGLRGVNRGMVTTLIRETPGFGVYFLAYDLLTR----SLGCEPDDPYMIPKLLFAGGMSGIASWLSTYPVDVIKSRLQADGVGGKYQYSSIMDCTRKSIQREGFRVFTRGLTSTLLRAFPVNAATFATVTLFLLYVRPD--------------------EGSKDCEAAH----------------------------------------HATLQQQAQPSSL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKZ5-1", "uniprot_id": "Q9VKZ5_DROME", "id": "Q9VKZ5-1", "name": "Mitochondrial basic amino acids transporter", "aln": "------------------MYPITFIYRVNNDKDPYR---------------------KRGSEIGDIQLKATSETFSPKMVVDFVAGLLGGAAGVLVGHPFDTVKVHLQTDDPRNPKYKGTFHCFRTIVQRDKFIGLYRGISSPMGGIGLVNAIVFGVYGNVQRLSN--------------------DPNSLTSHFFAGSIAGVAQGFVCAPMELAKTRLQLSTQVD----SGIKFTGPIHCLKYIVKTEGIRGAFKGLTATILRDIPGFASYFVSFEYLMR----QVET-PG----VAYTLMAGGCAGMSSWLACYPIDVVKTHMQADALGANAKYNGFIDCAMKGFRNEGPQYFFRGLNSTLIRAFPMNAACFFVVSWVLDICNAKGGMDSVMHSDQPLTLVNLDNKSQADLEATAPTVEEVVRKIITDNAMSHQYVSTPKDVVHSHYTSSTINIPKESKARLASDCNLK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38087-1", "uniprot_id": "YMC2_YEAST", "id": "P38087-1", "name": "Carrier protein YMC2, mitochondrial", "aln": "---------------------MSEEFPTPQLLDELE------------------------DQQKVTTPNEKRELSSNRVLKDIFAGTIGGIAQVLVGQPFDTTKVRLQTATTR----TTTLEVLRNLVKNEGVFAFYKGALTPLLGVGICVSVQFGVNEAMKRFFQNYNASKNPNMSSQDVDLSRSNTLPLSQYYVCGLTGGVVNSFLASPIEQIRIRLQTQTSNG----GDREFKGPWDCIKKLKAQG---GLMRGLFPTMIRAGHGLGTYFLVYEALVAREIG--TGLTRNEIPPWKLCLFGAFSGTMLWLTVYPLDVVKSIIQNDDLRKPKYKNSISYVAKTIYAKEGIRAFFKGFGPTMVRSAPVNGATFLTFELVMRFLGEE------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32331-1", "uniprot_id": "YMC1_YEAST", "id": "P32331-1", "name": "Mitochondrial glycine transporter YMC1", "aln": "---------------------MSEEFPSPQLIDDLE------------------------EHP---------QHDNARVVKDLLAGTAGGIAQVLVGQPFDTTKVRLQTSSTP----TTAMEVVRKLLANEGPRGFYKGTLTPLIGVGACVSLQFGVNEAMKRFFHHRNA----DMSS---------TLSLPQYYACGVTGGIVNSFLASPIEHVRIRLQTQTGSG----TNAEFKGPLECIKKLRHNK---ALLRGLTPTILREGHGCGTYFLVYEALIANQMNKRRGLERKDIPAWKLCIFGALSGTALWLMVYPLDVIKSVMQTDNLQKPKFGNSISSVAKTLYANGGIGAFFKGFGPTMLRAAPANGATFATFELAMRLLG--------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:. .* * *:**:*** .**:**. ::. .:.:: .: .:*:* :*: *: :: *** * .* : .* .* : .:..*:* : *:* . :... .*: : . :*: .*::* . . **: :: : : *. :* ** **:**:*: :* * : .: * * :*: .*::*: * *.* * .. : ", "identical_positions": 54, "similar_positions": 79, "identity": "11.46%" }, { "cls_id": "homologset.agr.MGI:2444912", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQV3-1", "uniprot_id": "D3ZQV3_RAT", "id": "D3ZQV3-1", "name": "", "aln": "----MTPVNVALIRDTKWLTLEVCREFQRGTCSRADTECRFAHPPRVCHVENGRVVACYDSLKGRCTREN--CKYLHPPPHLKSQLEINGRNNLIQQKTAAAMFAQQMQLMLQNAQMSSLASFPMNPSLAANPTMAFNPYIPH--PGMGLVPAELLPNGPVLISGNPP-LALS-GVPGPKPPRTDRLEVCREFQRGNCTRGESECRYAHPTDVSMIEVTDNTVTICMDYIKGRCSREKCKYFHPPPHLQAKLRAAHHQMNHSAAANAMALPPGALQLIPKRSALDKVNGATPVFNPSVFHCQQALANMQIPQPAFIPTGPILCMTPASTF------------------------------------VPMMHGATPSTMSAATPPAGNVPYVPTTTGNQLKY--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R003-1", "uniprot_id": "MBNL3_MOUSE", "id": "Q8R003-1", "name": "Muscleblind-like protein 3", "aln": "----MTPVNVALIRDTKWLTLEVCREFQRGTCSRADAECRFAHPPRVCHVENGRVVACFDSLKGRCTREN--CKYLHPPPHLKSQLEVNGRNNLIQQKTAAAMFAQHMQLMLQNAQMSSLASFPMNPSLAANPAMAFNPYMTH--PGMGLVPAELLPNGPVLISGNPP-LALP-GVPGPKPIRTDRLEVCREFQRGNCTRGESECRYAHPTDVSMIEVTDNSVTICMDYIKGRCSREKCKYFHPPPHLQAKLRAAHHQMNHS-AANAMALPHGALQLIPKRSALDKANGATPVFNPSVFHCQQALANMQIPQQAFIPT------------------------------------------------VPMMHGATPSTVSTATPPASNVPYVPTTTGNQLKY--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUK0-1", "uniprot_id": "MBNL3_HUMAN", "id": "Q9NUK0-1", "name": "Muscleblind-like protein 3", "aln": "----MTAVNVALIRDTKWLTLEVCREFQRGTCSRADADCKFAHPPRVCHVENGRVVACFDSLKGRCTREN--CKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQLMLQNAQMSSLGSFPMTPSIPANPPMAFNPYIPH--PGMGLVPAELVPNTPVLIPGNPP-LAMP-GAVGPKLMRSDKLEVCREFQRGNCTRGENDCRYAHPTDASMIEASDNTVTICMDYIKGRCSREKCKYFHPPAHLQARLKAAHHQMNHS-AASAMALQPGTLQLIPKRSALEKPNGATPVFNPTVFHCQQALTNLQLPQPAFIPAGPILCMAPASNI------------------------------------VPMMHGATPTTVSAATTPATSVPFAAPTTGNQLKF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AGP9-1", "uniprot_id": "A0A8M3AGP9_DANRE", "id": "A0A8M3AGP9-1", "name": "", "aln": "-----MAVNVTMGRDTKWLTLEVCREFQRGTCSRSDSECKFAHPSRTCHVENGRVIACFDSLKGRCTRDN--CKYLHPPPHLKTQLEINGRNNLIQQKTAAAMLAQQMQFMLPGAQLQPITSFPVTPSLANSPSMAFSPYLSHVSPGISLMP-ELLPSAPVLVPGSPTGITMGNGNSTQKHVRTDKLEVCREFQRGNCTRGENDCRYAHPMEAAMVDGSENSVIVCMDYIKGRCTRDKCKYFHPPAHLQARIKAAQHQASQN--AAAMALPPGAMQQLPKRPTLEKSNGAAAVFNPSMFHYQQALASMQLQQPAFIPTGSVFCMAPSGGIGLFKPPGPMTEGRWERRDWTGCRAPQSRYLSGPGHTVPMMHGATTSTVSSATTPVTNVPFAESATSNQTPPRY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O16011-1", "uniprot_id": "MBL_DROME", "id": "O16011-1", "name": "Protein muscleblind", "aln": "MANVVNMNSLLNGKDSRWLQLEVCREFQRNKCSRQDTECKFAHPPANVEVQNGKVTACYDSIKGRCNRDKPPCKYFHPPQHLKDQLLINGRNHLALKNALMQQMGIAPGQPVISGQVPAVATNPYLTGIPAN---SYSPYYTTG----HLVPALLGPDP--VTSQLGPVVPQTVQVAQQKIPRSDRLETS---------------------------------------------PLAAHHHQQQQQLQHQLNNINNNNNHS--TAGAAATSTTATTTTNNAAAAAAAAAAAAAAAVMGHHTLEVGKKRAADTTDMFP-------------------------------------------------LVFFCSFPSPCVFAFLNCSIFGFLRLWFSLFNLRH-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :*::** *********..*** *::*:****. .*:**:* **:**:****.*:: ***:*** *** ** :****:* ::: :. : ..*: .: : * ..:. . ::.** . *:* * *. : . . :. * *:*:**.. .::.: :** ::. ::: .:. : . * : .:..: .*:.. . : * : . : : : : . ::. : .:. * . : . ", "identical_positions": 69, "similar_positions": 100, "identity": "17.12%" }, { "cls_id": "homologset.agr.MGI:2444913", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZM4-1", "uniprot_id": "A0A0G2JZM4_RAT", "id": "A0A0G2JZM4-1", "name": "", "aln": "MSFRFSGGSR-VCSRAGSVRLSRGGAGFVAGNVCVGPGAESSFSCTLAGISSGGSFGNEGSSRGN--SVGFINNEPGLFSGNEKVAMQNLNDRLALYLNHVSSLEEANTDLEKKIEDWYEKCRPGKGRRLDHDCSRYFPVIEDLKRQILSMTTCNANLVLQNDNARLTADDFKMKYENELALHQSVEADTNGLRRVLDELTLSTTDLEIQREALSEELTYLQKNHEEEMGVLQNASGGNINVEMNAAPGLDLTAMLNNMRAEYEDLAEQNRKDAEASFKEKSASLQQQISDDAGAITAARNELMELKRNLQTLEIELQSITAMKQSYESSLAETEGNYYAQLQQIQEQIGLREEQLQQTRTETESQKLEHEQLLGIKTCLEKEIDTYCNLLDREEQKSESTGYKPKDRKPASEVN---DSAEETFARTVAEELDQLGNLLSLRVHSVEEKSSKISNITMEQWLPSKAP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TRJ4-1", "uniprot_id": "K1C26_MOUSE", "id": "Q3TRJ4-1", "name": "Keratin, type I cytoskeletal 26", "aln": "MSFRFSGRSR-VCSRAGSVRLSRGGAGFVAGNVCVGPGAEGSFSCTLGGLSSGGSFASEGSGRGS--SIGFLNNEPGLFSGNEKVAMQNLNDRLALYLNHVSALEEANTDLEKKIEGWYEKCGPGRGRRLDHDCSRYFSVIEDLKRQILSMTTCNANLVLQNDNARLTADDFKMKYENELALHQSVEADTNGLRRVLDELTLSTTDLEIQREALSEELTYLQKNHEEEMVVLQNASGGNINVEMNAAPSVDLTAMLNNMRAEYEDLAEQNRKDAEASFKEKSASLQQQISDDAGAATAARNELMELKRNLQTLEIELQSITAMKQSYENSLAETEGNYYAQLQQIQEQIGAREEQLQQIRTETEGQKLEHEQLLGIKTCLEKEIDTYCNLLDGEEQRSESTSYKPKDGKPASEFN---DSAEETFARTVAEELDQLGNLLSLRVHSVEEKSSKISNITMEQRVPSKAP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3Y9-1", "uniprot_id": "K1C26_HUMAN", "id": "Q7Z3Y9-1", "name": "Keratin, type I cytoskeletal 26", "aln": "MSFRLSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGWYEKCEPGSSREHDHDYSRYFSVIEDLKRQIISATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDSTEETIVKTVVEELDQIGNLLSLRVHSVEEKSSKISNITVEQRVPSKAP", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:** ** :***:** *** **:**********.**..****** *:****** ..*.. *. . **:.** .*:******:********* **:** :*****:***:**:.***** ** .*. *** ****.*********:* * ***.:**************::*********:******.***********.******* *:********:*.***** *** ::***:******:*.:***.:********************* *:*:**:*******. ** ******* ***************: *:*:*** ********* ******:*** ****** *****.****:****.:* ****** ****** **::*:** **.*. :*... * **:***:.:**.*****:**********************:** :*****", "identical_positions": 348, "similar_positions": 76, "identity": "74.36%" }, { "cls_id": "homologset.agr.MGI:2444918", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BG80-1", "uniprot_id": "FBX46_MOUSE", "id": "Q8BG80-1", "name": "F-box only protein 46", "aln": "MDRGSLLPFQLWCPRPFSKYSQNQPRPPSTALKPPVCP------------DTSSGTEPDHRPAHLESTPPAVAAEAPTSQPAPLLSTAASGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGS--SRASSMKVKGHWGSDSSKAKRRRRCLEPTKAPPDQGGREGTPATE--VTPTSSGDDVDLVSVAEMVALVEQRAALALQ-------SYPRPSTPAPVVFVSAD-QGGPAKGLGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEER--------------PGPGPGEVRIAFRISNVREPHSPDGNLPNGGGGRPGCAYPGSPGPGTRAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGETPAPTRPEDTPPAPPPPPARDCGA----SGFHVDVVVTGVVDACIFFGKDGTKNVKEETVCLTVS-------PEEPPPPGQLFFLQSRGPEGPPEPPP-------------ADIPSTVPGPDD----SEGTTDTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGVGGGRAGREEGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLY2-1", "uniprot_id": "FBX46_RAT", "id": "Q4KLY2-1", "name": "F-box only protein 46", "aln": "MDRGSLLPFQLWCPRPFSKYSQNQPRPPSATLKPPVCP------------DTSSGTEPDHRPAHLESTPPALAAEAPTSQHAPLLSTAASGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGG--SRASSMKVKGHWGSDSSKAKRRRRCLEPTKAPPDQGGQEGTPATE--VAPTSSGDDVDLLSVAEMVALVEQRAALALQ-------SYPRPSTPAPVVFVSAE-QGGPAKGLGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEER--------------PGPGPGEVRIAFRISNVREPQSPDGSLANGGGGRPACPYPGSPGPGTRAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGETPAPARPEDTPPAPPPPPARDCGA----SGFHVDVVVTGVVDACIFFGKDGTKNVKEETVCLTVS-------PEEPPPPGQLFFLQSRGPEGPPEPPP-------------ADTASKVPGPED----SEGTTDTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGVGGGRAGREEGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PJ61-1", "uniprot_id": "FBX46_HUMAN", "id": "Q6PJ61-1", "name": "F-box only protein 46", "aln": "MDRGSLLPFQLWCPRPFGTYSQNQPRPPSAALKPSACP------------EPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGG--SRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAE--EGPASAGEDVDLLSVAEMVALVEQRAALALQ-------SYPRPTTPAPVVFVSAE-QGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEER--------------PGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGA----SGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVS-------PEEPPPPGQLFFLQNRGPDGPPEPPP-------------ADSPATAPGPDD----AEGTADTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGPGGGRAGREEGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q1L8N6-1", "uniprot_id": "Q1L8N6_DANRE", "id": "Q1L8N6-1", "name": "", "aln": "MNRDTFSHIRLWCPRPFGTYSQNKPYSNGTVLNGTTTTHCKADDSGLTAIETHGVSEEQEEDVGTENTPPAASSTLLAPPLPASPSPNSQMEDGRVLLDTWYVIKPGNTKEKIAFFVAHQCNGAGIPRPSAMKVKGNWATDCTKAKRRRRCSSYDPPTKAQNVTVDVPAEPNLTDDGVVVSETDLLSVAEMVALVEQRTALALQGMVAQGQTSPYTVHQKPVVILSEPPSSTPASQSDFDLLQQQQESRRVAQTVAQFESRQQNLDSTTLRPELNGSGRDCIQTGESGTPSHGRGEVRIAFRVSS-LDPRTQSEPVGRPKCMFMSCGVGGGQ-AAARGKEKITCDLYQLVSPS-SRDPGALLAGSPKADPLGEGITDRPPSTTPDPNQDPASGEKATVARERVTGFHVEVVVTGAVDQCVFYGKDSTENVQEETVCFAMPNGAKSTDASEDPPPGQLFFLQSAATEDENCSAVNGGMRSLDCANNNGPLGATIERPDSPLATVDDCSDPPLCRLYRHVSHDFLEIRFQIQRLLEPRQYMLSLPDHIMVNIFSYLPTHSLAALKCTCHDFKTLIETYGVRATDSRWNQDPLYRDDPCKQCKRQYERGDVSLCRWHPKPYHHDLPYGRSYWMCCRRTDKDTPGCRVGLHDNNWVQPCELVQARK--RDDAR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*.:: ::*******..****:* . .:.*: .. . :. . :* :. . *.**** :: :. .. *. : ::*******************:********.*. .*.*:*****:*.:*.:******** . .. . . ** .:.**:************:***** : * . ***::* .. **. . : . :. ***::**:**::::. :. ** * . *. * ********:*. :*:: . : .* *. ..:*.*:*********:*** . *. : .:** .** : *. . * *.. : * :****:*****.** *:*:***.*:**:*****:::. ..* **********. ..:. .. . :. *:. :. :*..*****************:************ **:*::*:***:***::*********.** :**::*********.:************:::**:*****************************:*::*****:******** **: . : *::.*", "identical_positions": 301, "similar_positions": 166, "identity": "44.99%" }, { "cls_id": "homologset.agr.MGI:2444920", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96N06-1", "uniprot_id": "SPT33_HUMAN", "id": "Q96N06-1", "name": "Spermatogenesis-associated protein 33", "aln": "MVTHAAGARTFCEEQKKGSTYSVPKSKEKLMEKHSQEARQADRESEKPVDSLHPGAGTAKHPPPAASLEEKPDVKQKSSRKKVVVPQIIITRASNETLVSCSSSGSDQQRTIREPEDWGPYRRHRNPSTADAYNSHLKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C624-1", "uniprot_id": "SPT33_MOUSE", "id": "Q8C624-1", "name": "Spermatogenesis-associated protein 33", "aln": "MGQSKSKPREKKEEEK-STTTLVTKSKEKVMEK---EAKQSDKESQ-PAESLL--FATSKHSRPSSSSEDKPETKQRSSKKRSVIPQIIITRASNETLISYGIPDNDEQRTIREHADWGPYHRHRSPSTIAAYDVHNTE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GG17-1", "uniprot_id": "A0A8I6GG17_RAT", "id": "A0A8I6GG17-1", "name": "", "aln": "------------------------------MEK---ETKQSDKESQ-PAESMMFGSKTSKHSRPSSSSEGE-TRRPDAERHQGWVPCVRMNQET-----NLTQSKGQARREVSSHRSSSP-----GPQTRRS-------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** *::*:*:**: *.:*: *:**. *::* * : : :.::: :* : :.: : . . .: :* : . . .* .*.* : ", "identical_positions": 21, "similar_positions": 37, "identity": "15.11%" }, { "cls_id": "homologset.agr.MGI:2444923", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTA4-1", "uniprot_id": "D3ZTA4_RAT", "id": "D3ZTA4-1", "name": "RNA-binding protein 41", "aln": "---------MKRVNSCVKDEEHVL--------EELETEGERQLKSLLQHQLDTSVSIEECVSKKKSFAPGTMYKPFG-KEVAGTMTLSQFQTLHEKDQETASLRELGLNETEILIWKSHVSGEKRTKLR---ATPEAIQKRLEDIKERISERQ-RILCLPQRFSKSKQLTRREMEIEKSLFQGTDRHSFLKALYYQD--EPPKKNKGDPMNNLESFYHETIMK--KRLEEFQLLRGEPFPSHSLASAASVSD---SGTAESPSLLQDKGK-------QAAQGKGPSLHVAKVIDFPPE--------QCWTGPKKLKQPIEFIPEDEIQRNRLSEEEIRNIPMFSSYNPGEPNKVLYLKNLSPRVKERDLISLFARFQEKKGPLIQFQMMTGRMRGQAFITFPNK---DIAWQALHQINGYKLYGKILVIEFAKSRKQQSAAQ---CAPLIASATD-GRAEINGS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZV4-1", "uniprot_id": "RBM41_MOUSE", "id": "Q8JZV4-1", "name": "RNA-binding protein 41", "aln": "---------MKRVNSCVKDEEHVL--------EELETEGERQLKSLLQHQLDTSVSIEECVSKKKSFAPGTMYKPFG-KEAAGTMTLSQFQTLHEKDQETASLRELGLNETEILIWKSHVSGEKRTKLR---ATPEAIQKRLEDIKERISERQ-RILCLPQRFSKSKQLTRREMEIEKSLFQGTDRHSFLKALYYQD--EPPKKNKGDPMNNLEHFYRETIMK--KRLEEFQLLRGESFACHSLVSAASVSG---SGTAEKPSLLQDKGK-------QAAQGKGPRLHVAKLIDFPTE--------QYWTGPKTLKQPIEFIPEDEIQRNRLSEEEIRNIPMFSSYNPGEPNKVLYLKNLSPRVKERDLISLFARFQEKKGPPIQFRMMTGRMRGQAFLTFPNK---DIAWQALHQINGYKLYGKILVIEFAKSKKQQSAVQ---RSSLITSAPD-GRTEINGS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96IZ5-1", "uniprot_id": "RBM41_HUMAN", "id": "Q96IZ5-1", "name": "RNA-binding protein 41", "aln": "---------MKRVNSCVKSDEHVL--------EELETEGERQLKSLLQHQLDTSVSIEECMSKKESFAPGTMYKPFG-KEAAGTMTLSQFQTLHEKDQETASLRELGLNETEILIWKSHVSGEKKTKLR---ATPEAIQNRLQDIEERISERQ-RILCLPQRFAKSKQLTRREMEIEKSLFQGADRHSFLKALYYQD--EPQKKNKGDPMNNLESFYQEMIMK--KRLEEFQLMRGEPFASHSLVSATSVGD---SGTAESPSLLQDKGK-------QAAQGKGPSLHVANVIDFSPE--------QCWTGPKKLTQPIEFVPEDEIQRNRLSEEEIRKIPMFSSYNPGEPNKVLYLKNLSPRVTERDLVSLFARFQEKKGPPIQFRMMTGRMRGQAFITFPNK---EIAWQALHLVNGYKLHGKILVIEFGKNKKQRSNLQ---ATSLISCATG-STTEISGS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I8N3-1", "uniprot_id": "A0AC58I8N3_DANRE", "id": "A0AC58I8N3-1", "name": "", "aln": "---------MKRVTRHACDDVPIP--------EEQETEGQRQLHNLLLQQLDTDVDIDRCVAKKKCFAPAAVYKPFG-EQAAGVRSLSQFQALQDGDQELAALRELGLTDAEILLWRSREQPESSLKDRGVCVAPEARNERLQAIRDKMAAHA-ELLSRPQRFSSSRALSRREMEIEKALFQGSDRSSFLTALYHQDGDSHVSQQRATSPKTMDHFYKDFLEEQNKTFGDVSTLQPETVTNIQCTSSDSKSDQSQSPTVSESGLPEYQHKCTKSDIVNQPQPQEKSIQPVKITVSQSVGKLNSAFVQGHNGPVALSGRIKEVSDEEIKSNRETEEAIRNIPRFKNYQRGKPSKVLCVKNISPRASLAQLVSLFSRFQKDESQPILYRLLTGRLKGQAFITLADA---EIAQAALDLLNGYKLLEKPLVIEFGRARSKETDLQTDETSPLPNSIIQHERARINCKTIPTVFI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4LGA2-1", "uniprot_id": "A0A0B4LGA2_DROME", "id": "A0A0B4LGA2-1", "name": "RRM domain-containing protein", "aln": "MSALSSKLLMKRMPCSLDELAQLIRECKLILPRSLNTYGRKRVLLEYADPEEAAKALEQLQELSESLDKPLCISVFGPRPSSGAASASSKSTQTSGAGNGGAVS--GFPDIDKYVRRLYACNNQCDFTQ---PPPPYLSYSYPPINGEILARIGQSLQTNSHFYNQVLHLMNRMNLEPPFEKRPD--GLMAQMHRQHVGTQTELIPSESESELESDDGE------QKLAKRQRLLLAPASEEARAKTLKRARQMLQQAAQLASHTKPKLT------VQKPSFDAPKIEMKLPETLVPP--------PIHPERRESISKPETGASTSKAVRRLSTSALEALPVYKNYKTGDPSNKLYIKNLAKSVDEQQLRELYAKYTAASKLDIKV-MHQGRMKGQAFVTFLDANNPEIIAQALNETNGLLWHDKPMIVCYGKQQ------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***: . : .. :* *.::: . :: ::. .:.: . ** . :*. : *. .: . : .:: *: : : : : :. : .* . *. .: : . * .:* .. ..*::* .: : .* .:: :: *. . . . . :: : : : . . : . . ..: . . . :.. .. : : . : .. . :. . : .. . .* : . :. :* :..*: *.*.: * :**:: . :* .*:::: . * : **::****:*: : :* **. ** * ::: :.: : ", "identical_positions": 42, "similar_positions": 144, "identity": "8.92%" }, { "cls_id": "homologset.agr.MGI:2444925", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LFI7-1", "uniprot_id": "A0ABK0LFI7_RAT", "id": "A0ABK0LFI7-1", "name": "", "aln": "MSPPTVPP----TGVDGVS--AYLMKKRHTHKKQRRKPTFLTH---RNIVGCRIQHGWKEGNE-PVEQWKGTVLEQVSVKPTLYIIKYDGKDSVYGLELHRDKRVLALEILPERVPSPRI-DSRLADSLVGKAVGHVFEGEHGKKDEWKGMVLARAPIMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIPDSNYYFPTAEQEPGEVLDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVYGLVKTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1L2-1", "uniprot_id": "SPIN4_MOUSE", "id": "Q8K1L2-1", "name": "Spindlin-4", "aln": "MSPPTVPP----TGVDGVS--AYLMKKRHTHKKQRRKPTFLTH---RNIVGCRIQHGWKEGNE-PVEQWKGTVLEQVSVKPTLYIIKYDGKDSVYGLELHRDKRVLALEILPERVPSPRI-DSRLADSLVGKAVGHVFEGEHGKKDEWKGMVLARAPIMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIPDSNYYFPAAEQEPGEVLDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVYGLVKTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q56A73-1", "uniprot_id": "SPIN4_HUMAN", "id": "Q56A73-1", "name": "Spindlin-4", "aln": "MSPPTVPP----MGVDGVS--AYLMKKRHTHRKQRRKPTFLTR---RNIVGCRIQHGWKEGNE-PVEQWKGTVLEQVSVKPTLYIIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRI-DSRLADSLIGKAVEHVFEGEHGTKDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIPDSNYYFPTAEQEPGEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVYGLVKTP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R8A6-1", "uniprot_id": "F1R8A6_DANRE", "id": "F1R8A6-1", "name": "", "aln": "MESPYRTHRSKHTGVRSVSSGRSTMKKKNSHKNRHARAVSPVRPLGQSVVGCRIQHLWKEDVSSPVSLWKGTVLSQVEVDDSLFLIKYDGVDCVYGLQLFTDDRVRDLELQPGQIASFRVSDSRLADRLLGRPVVHLFETDDGSKDEWKGLVLSRAPSMPAWFFITYEKDPMLYMYQLMQDYRDGDLRLLPDSDE--AAELREAGEVSETLVGKQVECLNKDGAQKLGTIIQQVQAKPSVYFIKFNDDYHIYVYDMVGS-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..* . ** .** ***:::*:::: :.. .: :.:******* ***. . **. ******.**.*. :*::***** *.****:*. *.** **: * ::.: *: ****** *:*:.* *:** :.*.******:**:*** * :**:*******:**** *::**:*****::***: .: :*.*** ::******* :.**::: * :*:** **********:** *****.:* : ", "identical_positions": 134, "similar_positions": 73, "identity": "51.54%" }, { "cls_id": "homologset.agr.MGI:2444926", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZH41-1", "uniprot_id": "D3ZH41_RAT", "id": "D3ZH41-1", "name": "", "aln": "MPSAKQRGSKGGHGAASPSDKGAHPSGGADDVAKKPPPAPQQPQPP-----APHPPQHPQNQAH-RGGHRG------RSS---------TAAAAASSASCSRRLGRLLNFLFYLSLVAAAAFSGWYVHHVLEEVQQVRRGHQDFSRQRDELGQGLQGVEQKVQSLQAAVGTFESILRSSQHKQDLTEKAVKEGESEINRISEVLQKLQNEILKDLSDGIHVVKDARERDFTSLENTVEERLTELTKSINDNIAIFTDVQKRSQKEINEVKMKVASLEESKGDRSQDVKVLKEAVKEVQASMKSRERDIEALKSSLQTMESDVYTEVRELVSLKQEQQAFKQAADSERLALQALTEKLLQSEESSSRLPEDIRRLEEELQQLKVGAHGSEEAVVFRDSKAFDELQKQMEGLGARLQYVEDGVYSMQVASASHTESLESLLSKSQEYEQRLAMLQEHVESLGPI----SDLASTVRSLEETQLALSSDLKGLKQGLGELPGTVESLQ---EQVHLLLSQDPAQAAGLPPQDFLDRLSSLDNLKSSVSQVESDLKMLRTAVDSLVAYSVKIETNENSLESAKGLLDDLRNDLDRLFVKVEKIHEKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMK4-1", "uniprot_id": "CKAP4_MOUSE", "id": "Q8BMK4-1", "name": "Cytoskeleton-associated protein 4", "aln": "MPSAKQRGSKGGHGAASPSDKGAHPSGGADDVAKKPPAAPQQPQPP-----APHPPQHPQNQAH-RGGHRG------RSS---------AATANASSASCSRRLGRVLNFLFYLSLVAAAAFSGWYVHHVLEEVQQVRRGHQDFSRQRDELGQGLQGVEQKVQSLQATFGTFESLLRNSQHKQDLTEKAVKEGESELNRISEVLQKLQNEILKDLSDGIHVVKDARERDFTSLENTVEERLTELTKSINDNIAIFTDVQKRSQKEINEVKMKVASLEESKGDRSQDVKTLKDAVKEVQASMMSRERDIEALKSSLQTMESDVYTEVRELVSLKQEQQAFKQAADSERLALQALTEKLLRSEESSSRLPEDIRRLEEELQQLKVGAHGSEEGAVFKDSKALEELQRQIEGLGARLQYVEDGVYSMQVASARHTESLESLLSKSQEYEQRLAMLQEHVGNLGSS----SDLASTVRSLGETQLALSSDLKELKQSLGELPGTVESLQ---EQVLSLLSQDQAQAEGLPPQDFLDRLSSLDNLKSSVSQVESDLKMLRTAVDSLVAYSVKIETNENNLESAKGLLDDLRNDLDRLFLKVEKIHEKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07065-1", "uniprot_id": "CKAP4_HUMAN", "id": "Q07065-1", "name": "Cytoskeleton-associated protein 4", "aln": "MPSAKQRGSKGGHGAASPSEKGAHPSGGADDVAKKPPPAPQQPPPPPAPHPQQHPQQHPQNQAHGKGGHRGGGGGGGKSSSSSSASAAAAAAAASSSASCSRRLGRALNFLFYLALVAAAAFSGWCVHHVLEEVQQVRRSHQDFSRQREELGQGLQGVEQKVQSLQATFGTFESILRSSQHKQDLTEKAVKQGESEVSRISEVLQKLQNEILKDLSDGIHVVKDARERDFTSLENTVEERLTELTKSINDNIAIFTEVQKRSQKEINDMKAKVASLEESEGNK-QDLKALKEAVKEIQTSAKSREWDMEALRSTLQTMESDIYTEVRELVSLKQEQQAFKEAADTERLALQALTEKLLRSEESVSRLPEEIRRLEEELRQLKSDSHGPKEDGGFRHSEAFEALQQKSQGLDSRLQHVEDGVLSMQVASARQTESLESLLSKSQEHEQRLAALQGRLEGLGSSEADQDGLASTVRSLGETQLVLYGDVEELKRSVGELPSTVESLQKVQEQVHTLLSQDQAQAARLPPQDFLDRLSSLDNLKASVSQVEADLKMLRTAVDSLVAYSVKIETNENNLESAKGLLDDLRNDLDRLFVKVEKIHEKV", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******************:*****************.***** ** ** ******** :***** :** :*:* :*********** *******:********** *************.********:******************:.*****:**.*************:****:.**********************************************************:**********::* ********:*:: **:*.**:****:*:* *** *:***:*:*******:******************:***:*************:**** *****:********:*** .:**.:* *:.*:*:: **:: :**.:***:***** ******* :*************:***** ** :: .**. ..******** ****.* .*:: **:.:****.****** *** ***** *** *****************:******:************************.*******************:********:", "identical_positions": 469, "similar_positions": 73, "identity": "77.78%" }, { "cls_id": "homologset.agr.MGI:2444928", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A254-1", "uniprot_id": "D4A254_RAT", "id": "D4A254-1", "name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGEVEPVPAGSLEPPEPPEAAAPRRPGGIRVLKRNMKHNGSRNCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTTSSSSSSSSSSSSSDLHLVLCTVETPASEICAGEGRESLYLQLHG--------DLVRRLEPTERPLQIVYDYLSRLGFEDPVRIQEEATNPDLSCMIRFYGEKPCQMDHLDRILLSGIYNVRKGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILP--------------LVGGKIEEVKRRQHSLAFSSAGAQAQTYHVSFETLAEYQRWQRQASKVVSQRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPVLLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNVLTALPDELGNLQQLTSLGISFNNFSQIPEVLEKLTMLDKVVMAGNRLEILNLGVLTRMNHVKHVDLRMNHLKTVIIENLEGNKHITHMDLRDNQLTDLDLSSLCSLEQLHCERNQLRELTLSGFSLRNLYANW---NKLTAVNVYPVPSLLTSLELSRNLLECIP-DWACEAKKLEILDISYNLLTEVPMRILSS--LSLRKLMVGHNHIHVLPALVEHIP-LEVLDVQHNTLSRLPDTLFSKALN-LRYLN----ASANSLESLPSACAGEESLSVLQLLYLTNNLLTDQCIPVLVGHPHLRVLHLANNQLQTFPASKLNKLEQLEELNLSGNKLKAIP-TTIANCKRLHTLVAHAN-NISIFPEILQLPQIQFVDLSCNDLTEILIPETLP------ATLQDLDLTGNTNLVLEHKT----------------------LDMFSHITTLKIDQKPLPTTDSTVTSTFWSHGLAEMAGQRNKLCVSALAMDNFAEGVGAVYGMFDGDRNE---------ELPRLLQCTMADVLLEEVQHSTSDTVFMANTFLVSHRKLGMAGQKLGSSALLCYIRPDTADPTSSFS----------LTVANVGTCQAVLCRGGKPVPLSKVFSLEHDPEEAQRVKDQKAIITEDNKVNGVTCCTRMLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYLEAVSAVR-HVQDPLAAAKKLCTLAQSYGCQDNVGAMVVYLNIGEEG------------------CTCEMHGLALPG---------------PVGFAS---TATIKDAPKPTTPSSSSGIASELSSEVSTSEVSSEVGSTASDEHNTVGLETSLLPRPERRCSLHPVPSAG-------------------------------TFQRQPSCATFSSNQSD--NGLDSDDDQPVEGVITNGSRVEVEVDIHCCRGRE-------SENSPTLPKNSSYPCSEEHARGLGFGIRRQNSVNSGILLPVNKD-KMELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATEAPKR-----KTGYFAAPTQLEPEDQFVVPRDLEDEVKEQMKQHQESRPEP-------------------EPREEDRTEPLQEFDTAL-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BXA7-1", "uniprot_id": "PHLP2_MOUSE", "id": "Q8BXA7-1", "name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKHNGSRTCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTSSSSSSSS----SSDLHLVLCTVETPASEICAGEGRESLYLQLHG--------DLVRRLEPSERPLQIVYDYLSRLGFEDPVRIQEEATNPDLSCMIRFYGEKPCQMDHLDRILLSGIYNVRKGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILP--------------LVGGKIEEVKRRQHSLAFSSAGAQAQTYHVSFETLAEYQRWQRQASKVVSQRMSTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLHKFSQLKGLNLSHNKLGLFPVLLCEISTLTELSLSCNGFHDLPSQIGKLLNLQTLSLDGNGLTALPDELGNLRQLTSLGISFNDFRHIPEVLEKLTMLDKVAMAGNRLEVLNLGALTRMSQVKHVDLRMNHLKTVITENMEGNKHITHMDLRDNQLTDLDLSSLCSLEQLHCERNQLRELTLSGFSLRTLYASW---NRLTAVNVYPVPSLLTSLELSQNLLECVP-DWACEAKKLEILDISHNLLTEVPMRILSS--LSLRKLMVGHNHIHVLPALVEHIP-LEVLDIQHNTLSRLPDTLFSKALN-LRYLN----ASANSLESLPSACAGEESLSVLQLLYLTSNLLTDQCIPVLVGHPHLRVLHLANNQLQTFPASKLNKLEQLEELNLSGNKLTAIP-TTIANCKRLHTLVAHAN-NISIFPEILQLPQIQFVDLSCNDLTEILIPEALP------ATLQDLDLTGNTNLVLEHKT----------------------LDMFSHITALKIDQKPLPATDSAVTSTFWSHGLAEMAGQRNKLCVSALAMDNFAEGVGAVYGMFDGDRNE---------ELPRLLQCTMADVLLEEVQHSTNDTVFMTNTFLVSHRKLGMAGQKLGSSALLCYIRPDTADPTSSFS----------LTVANVGMCQAVLCRGGKPVPLSKVFSLEHDPEEAQRVKDQKAIITEDNKVNGVTCCTRLLGCTYLYPWILPKPHIASTPLTIQDELLILGNKALWEHLSYLEAVNAVR-HVQDPLAAAKKLCTLAQSYGCQDNVGAMVVYLNIGEEG------------------CTCEMNGLTLPG---------------PVGFAS---TAALKDTPKPTTPSSSSGIASEFSSEMSTSEVSSEVGSTASDEHNTVGLEASLLPRPERRCSLHPASSAG-------------------------------VFQRQPSCATFSSNQSD--NGLDSDDDQPVEGVITNGSRVEVEVDIHCCRGRE-------PESSPPLPKNSSNACSEERARGAGFGIRRQNSVNSGILLPANRD-KMELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATEAPKR-----KTGYFAAPTQLEPEDQFVVPRDLEEEVKEQMKQHQEGRPEP-------------------EPRGEERTEPLEEFDTAL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZVD8-1", "uniprot_id": "PHLP2_HUMAN", "id": "Q6ZVD8-1", "name": "PH domain leucine-rich repeat-containing protein phosphatase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRNGSRNCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTATTTTTTSSSSSSSSS-SSDLHLVLCTVETPASEICAGEGRESLYLQLHG--------DLVRRLEPTERPLQIVYDYLSRLGFDDPVRIQEEATNPDLGCMIRFYGEKPCHMDRLDRILLSGIYNVRKGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILP--------------LVGGKIEEVKRRQYSLAFSSAGAQAQTYHVSFETLAEYQRWQRQASKVVSQRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQLHCGRNQLRELTLSGFSLRTLYASS---NRLTAVNVYPVPSLLTFLDLSRNLLECVP-DWACEAKKIEVLDVSYNLLTEVPVRILSS--LSLRKLMLGHNHVQNLPTLVEHIP-LEVLDLQHNALTRLPDTLFSKALN-LRYLN----ASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLHLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIP-TTIANCKRLHTLVAHSN-NISIFPEILQLPQIQFVDLSCNDLTEILIPEALP------ATLQDLDLTGNTNLVLEHKT----------------------LDIFSHITTLKIDQKPLPTTDSTVTSTFWSHGLAEMAGQRNKLCVSALAMDSFAEGVGAVYGMFDGDRNE---------ELPRLLQCTMADVLLEEVQQSTNDTVFMANTFLVSHRKLGMAGQKLGSSALLCYIRPDTADPASSFS----------LTVANVGTCQAVLCRGGKPVPLSKVFSLEQDPEEAQRVKDQKAIITEDNKVNGVTCCTRMLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVR-HVQDPLAAAKKLCTLAQSYGCQDNVGAMVVYLNIGEEG------------------CTCEMNGLTLPG---------------PVGFAS---TTTIKDAPKPATPSSSSGIASEFSSEMSTSEVSSEVGSTASDEHNAGGLDTALLPRPERRCSLHPTPTSG-------------------------------LFQRQPSSATFSSNQSD--NGLDSDDDQPVEGVITNGSKVEVEVDIHCCRGRD-------LENSPPLIESSPTLCSEEHARGSCFGIRRQNSVNSGMLLPMSKD-RMELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATEVPKR-----KTGYFAAPTQMEPEDQFVVPHDLEEEVKEQMKQHQDSRLEP-------------------EPHEEDRTEPPEEFDTAL-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VJ07-1", "uniprot_id": "PHLPP_DROME", "id": "Q9VJ07-1", "name": "Protein phosphatase PHLPP-like protein", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLKATRKQADPYKSKLKVSASHS-----------------------------------------------------------------------------------------------GPHPLPVEVTAAEEEQAATFG----QTSPQKLS---------------------------LKGSQLGG----------------------------SILIGNYN---YLTQLEVCENEMEVLDLSSLAQLETLKCSRNKLMELIINGTNLQTLVADHNYLHNISTTNTHPVPLKLQRIDISHNNFSELP-NWVGACASLTAINASHNRLNNVAVLLRNYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPDNFFAVTHARLETLN----VSCNKLSTLP--RYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEILVLSGNMLQQLP-EEVATLGQLRVLRCCNN-LLLCTPQLAKLAMLKVLDLSHNHLDRVNLLALVPS-----RNLKYLDLSGNLQLQVDEQQ----------------------FKVCQSQSQRHWS---LVDVSGNNRAALPTTKIRQVSAQRNQNKTSGPWTMGFAETPGSGD---CRKLSV---------YQLRAANYGGSDEALYGMFEALEGRGRAAQEMSHLVPDLMKQEQMVKDSAVRDYMKFTLLAAQQQCG----------SVRS---AALFHLTRTRAPSKVRPLKSKRYVLRMASTGGLDAYLIRRTSQLR----LTKPDVIQKDQIHSMPDPHVLELILSNDDEYLVVGNAQLWSVMDIDRAAREIR-KEENSLLAAKRLVDIAQSFAAAESLSVIVVRFRHLGTD------------------VDHLIRELKQSVRKKP----------QPVSLPLSSGSVCKRTCCDRSNACRHRAIEQEPLAGRSSPSGQSDRDLLAKDKDDEFVLAHARVLQEEQQLEMLDETESVSESV---------------------------LSEEQFKCWEYMLEQNT--QLLFDKELNTISKSFTKQRTVPNAIMAATVLPER-------NDFTSNLMRTVTNKFISTSTPQLPQPITTSVPLGSYHQVKQAPPGHFGSALSFQQAHSYGYNLFDAKPRPKFHGG----TVKRSAGP-----NSAYFGSLQRLMPYN-FEYDFAVTQERERNILDEEEHDDDD-------------------FNEHESRMRKYWGVATTEL----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08678-1", "uniprot_id": "CYAA_YEAST", "id": "P08678-1", "name": "Adenylate cyclase", "aln": "MSSKPDTGSEISGPQRQEEQEQQIEQSSPTEANDRSIHDEVPKVKKRHEQNSGHKSRRNSAYSYYSPRSLSMTKSRESITPNGMDDVSISNVEHPRPTEPKIKRGPYLLKKTLSSLSMTSANSTHDDNKDHGYALNSSKTHNYTSTHNHHDGHHDHHHVQFFPNRKPSLAETLFKRFSGSNSHDGNKSGKESKVANLSLSTVNPAPANRKPSKDSTLSNHLADNVPSTLRRKVSSLVRGSSVHDINNGIADKQIRPKAVAQSENTLHSSDVPNSKRSHRKSFLLGSTSSSSSRRGSNVSSMTNSDSASMATSGSHVLQHNVSNVSPTTKSKDSVNSESADHTNNKSEKVTPEYNENIPENSNSDNKREATTPTIETPISCKPSLFRLDTNLEDVTDITKTVPPTAVNSTLNSTHGTETASPKTVIMPEGPRKSVSMADLSVAAAAPNGEFTSTSNDRSQWVAPQSWDVETKRKKTKPKGRSKSRRSSIDADELDPMSPGPPSKKDSRHHHDRKDNESMVTAGDSNSSFVDICKENVPNDSKTALDTKSVNRLKSNLAMSPPSIRYAPSNLDGDYDTSSTSSSLPSSSISSEDTSSCSDSSSYTNAYMEANREQDNKTPILNKTKSYTKKFTSSSVNMNSPDGAQSSGLLLQDEKDDEVECQLEHYYKDFSDLDPKRHYAIRIFNTDDTFTTLSCTPATTVEEIIPALKRKFNITAQGNFQISLKVGKLSKILRPTSKPILIERKLLLLNGYRKSDPLHIMGIEDLSFVFKFLFHPVTPSHFTPEQEQRIMRSEFVHVDLRNMDLTTPPIIFYQHTSEIESLDVSNNANIFLPLEFIESSIKLLSLRMVNIRASKFPSNITKAYKLVSLELQRNFIRKVPNSIMKLSNLTILNLQCNELESLPAGFVELKNLQLLDLSSNKFMHYPEVINYCTNLLQIDLSYNKIQSLP---QSTKYLVKLAKMNLSHNKLNFIGDLSEMTDLRTLNLRYNRISSIKTN-ASNLQNLFLTDNRISNFEDTLPKLRALEIQENPITSISFKDFYPKN--MTSLTLNKAQLSSIPGELLTKLSFLEKLELNQNNLTRLPQEISKL--TKLVFLSVARNKLEYIPPELSQLKSLRTLDLHSNNIRDFVDGMENLELTSLNISSNAFGNSSLENSFYHNMSYGSKLSKSLMFFIAADNQFDDAMWPLFNCFVNLKVLNLSYN---NFSDVSHMKLESITELYLSGNKLTTLSGDTVLKWSSLKTLMLNSNQMLSLPAELSNLSQLSVFDVGANQLKYNISNYHYDWNWRNNKELKYLNFSGNRRFEIKSFISHDIDADLSDLTVLPQLKVLGLMDVTLNTTKVPDENVNFRLRTTASIINGMRYGVADTLGQRDYVSSRDVTFERFRGNDDECLLCLHDSKNQNADYGHNISRIVRDIYDKILIRQLERYGDETDDNIKTALRFSFLQLNKEINGMLNSVDNGADVANLSYADLLSGACSTVIYIRGKKLFAANLGDCMAILSKNNGDYQTLTKQHLPTKREEYERIRISGGYVN-NGKLDGVVDVSRAVGFFDLLPHIHASPDISVVTLTKADEMLIVATHKLWEYMDVDTVCDIARENSTDPLRAAAELKDHAMAYGCTENITILCLALYENIQQQNRFTLNKNSLMTRRSTFEDTTLRRLQPEISPPTGNLAMVFTDIKSSTFLWELFPNAMRTAIKTHNDIMRRQLRIYGGYEVKTEGDAFMVAFPTPTSGLTWCLSVQLKLLDAQWPEEITSVQDGCQVTDRNGNIIYQGLSVRMGIHWGCPVPELDLVTQRMDYLGPMVNKAARVQGVADGGQIAMSSDFYSEFNKIMKYHERVVKGKESLKEVYGEEIIGEVLEREIAMLESIGWAFFDFGEHKLKGLETKELVTIAYPKILASRHEFASEDEQSKLINETMLFRLRVISNRLESIMSALSGGFIELDSRTEGSYIKFNPKVENGIMQSISEKDALLFFDHVITRIESSVALLHLRQQRCSGLEICRNDKTSARSNIFNVVDELLQMVKNAKDLST", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: .: . : :* .: : : : * : * :. . : . : ::: *.: :. . ..*: * *:: :: . .*: * . :: : :* : : :.: :. :* : : :: . * *..:. : . .* * :. *.:. : . : :. *::: * : : * : *. . *. . . .: * : :.* : * : :*::*:*: * :. : .: * **** * :. : . *:.* * : .:: :*. :...*:. *.* *: *:::** .: :. :.: : . : : : .**: * . . . * * . .. : : . . . . : . * : . . . : .:: :: ..*.: *: ** *::.. **. :. . * : :.* ** .* * ::.. :.: : : : :. * . : . : . . : .: : . * : . .: . :: : : . .:. : . . : : . . : : : : . . : : .: .: :: * : :: : :. : . . * . . ", "identical_positions": 68, "similar_positions": 248, "identity": "3.34%" }, { "cls_id": "homologset.agr.MGI:2444933", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M278-1", "uniprot_id": "F1M278_RAT", "id": "F1M278-1", "name": "", "aln": "MMESSKISFEDVAVDFSWDEWQLLSPTQKSLYRDVMLENCSSLVFLGNQTIKPDVAFKLDQEESRIMDEEILTQNFLEIWLNSNSEPWPQDKQDKLKRMERGNGDNVLEKLFQPSMNSVYLEMRFHICGTSEKNVKNPLNFFILKSNCGRIKS-KVSKKLLFYLKFDRSYSKRKFHDCNKYRKANSNESQLVTNQMTHSGIYLCMECGRIFNKKSQLTVHQRNHTGEKPYQCNGCGKTFAQKSLLALHQKSHSVEPDG-CDERQKAFSGKSLVIQQQRTHAGQKLCTH---GKAYSRKSQQNRQEMIHTMGKPYRCSDCGKAFSQKLKLIIHRRTHTGEKPYKCSECRKAFFWNSQLITHQRSHRGKKPYVCSKCKKAFRRNSLLIRHQRIHAVEKPQRSRECGEAFIRKAQLTKHRMTHTGEKSYQCYDCEEAFFKKSQLMRHQKSHLGERPLRCTECGKTFPEKSQLLTHQKSHLEERPLRCTECGKTFPEKLQLLTHQKSHLGERPHRCTECGKTFPEKLQLLTHQKSHLGERPHRCAECGKSFPGRSQLLTHQRTHTGEKPYKCSECGRGFSQRSSVVSHQRTHTGEKPYKCGDCGKAFTEKSSLLHHKRTHTGEKPFECSDCGKAFAWKPQLLRHQRIHTGEKPFECSECGKAFVQKVQLIKHQRHHTGEKTYKCNGCEKAFFEKTQLMIHQKIHTGERPYTCGKCGKSFTRKSHLMRHEPIHTRVKSYRCSQCGGIFNKKSHLIRHQKDHTVEAI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QAH2-1", "uniprot_id": "E9QAH2_MOUSE", "id": "E9QAH2-1", "name": "", "aln": "-MTESRISFEDVAVDFSWDQWQLLSPTQKSLYRDVMLENCSSLVFLGNQTTKPDVTFKLDQQESRIMDEECLSQNFLEIWLDSYSELWLQDEQDKPKRMERGNGDNVLEEVCHSSMNSVYLEMRFHICGTCGKNLKSPLNFFIPKGNRVRKKS-KVSKKLLFYLKFDKPYSKRKCHDCNKYRKANSNESQLVTKQRTHSGIFLCMECGRIFNKKSQLIVHQRNHTEEKPCQCNGYGKTFAQKSQLAIHQKTHSGEEP----ERQKAFGGKSLGLQQQRTHTGQKPYAR---GKTYSRKPTQNRPAMSHAVHKPYRCGDCGEVFSQKLKLIIHRSTHPGEKPYKCSECRKAFFWNSQLITHRRSHRGKKPYVCSECEKAFRRNSLLIRHQRIHTGEKPHRSRECGEAFIGKPQLAKHHMTHTGEK--KCYGFEEVFFKKSKLMRHQKSHLGEKPNRCAEFGKIFPEKSQLLTHQKSHS--------------------------------------------------------GERPYRCAECGKTFPGRSSLLSHQRTHTGEKPYKCNLCGRAFSQRSSIISHQRTHTGEKPFKCGDCGKAFTEKSNLLHHKRTHTGEKPFGCSDCGKAFAWKPHLLQHQRIHTGEKPFECSECGKAFVQKVQLIKHQRHHTGEKIYKCSSCEKAFFEKTQLTIHQKIHTGERPYTCGECGRSFTRNSHLMRHKPIHTRDKCYRCSQCGSIFNKKSHLIRHQKDHIIKAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86T29-1", "uniprot_id": "ZN605_HUMAN", "id": "Q86T29-1", "name": "Zinc finger protein 605", "aln": "-MIQSQISFEDVAVDFTLEEWQLLNPTQKNLYRDVMLENYSNLVFL-------------------------------EVWLD-NPKMWLRDNQDNLKSMERGHKYDVFGKIFNSSINIVHVGLRSHKCGTGEKSLKCPFDLLIPKNNCERKKIDELNKKLLFCIKPGRTHGGIKYCDCSTCRKSSNEEPWLTANHITHTGVYLCMECGRFFNKKSQLVIHQRTHTGEKPYQCSECGKAFSQKSLLTVHQRTHSGEKPHGCSECQKAFSRKSLLILHQRIHTGEKPYGCSECGKAFSRKSQLKRHQITHTIEKPYSCSECGKAFSQKLKLITHQRAHTGEKPYPCSHCGKAFFWKSQLITHQRTHTGKKPYGCGECQKAFSRNSLLIRHQRIHTGEKPYECNECGEAFIRKPQLIKHQITHTGEKNYRCSDCEEAFFKKSELIRHQKIHLGEKP------------------------------------------------------------------------------------YGCIQCGKTFFGKSQLLTHHRTHTGEKPYECSECGKAFTQKSSLISHQRTHTGEKPYECSECRKTFSEKSSLIHHQRTHTGEKPFECSECRKAFAWKPQLLRHQRIHTGEKPYECSECGKAFVQKVQLIKHQRNHTGEKTYGCSDCAKAFFEKAQLIIHQRIHTGERPYKCGECGKSFTRKSHLMRHQRIHTGDKYYGCNECGTTFNRKSQLMIHQRNHII---", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*:**********: ::****.****.********* *.**** *:**: .: * :*:**: * ****: :*: :: :.*:* *:: :* * *** *.:* *::::* *.* * * ::.***** :* .:.:. * **.. **:..:*. *.::: **:*::*******:******* :***.** *** **. **:*:*** *::**::** * * ****. *** : :** *:*:* **::***. :* : *:: *** *.:**:.******** *: :*.***** **.* *****:******:*:* ***** *.:*:*** ************: *** ...******* *.** **::****** :* . **.*****:*:**** ****:* : * :***:* *:*.**:*:*********:*. **:.*:*:**::***********::*.:* *:*:***.*:**:********* **:* *******:**:**********:********************:***** * *..* ******:** ***:********.**:**:****:******: *** * * *.:** **:**:*: **::* : ", "identical_positions": 388, "similar_positions": 151, "identity": "50.99%" }, { "cls_id": "homologset.agr.MGI:2444934", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q811R2-1", "uniprot_id": "PRGC2_RAT", "id": "Q811R2-1", "name": "Peroxisome proliferator-activated receptor gamma coactivator 1-beta", "aln": "MAGNDCGALLDEELSSFFLNYLSDTQGGESGEE-----QLCADLPELDLSQLDASDFDSATCFGELQWCPETSETEPSQYSPDDSEFFQIDSENEALLAALTKTLDDIPEDDVG-LAAFPGLDEGDTPSCTPASPAPLSVPPSPALERLLSPVSEVDELSLLQKLLLATSSPTASSDALKDGATWSQTS--LSSRSQRPCVKVDG--TQDKKTPMLRSQSRPCTELHKHLTSVLPCPRGKACSPPPHPSPQLLSKEDEE-VGEDCPSPWPAPASPQDSLGQDTANPNSAQVPKD-DVRAMVQLIRYMHTYCLPQRKLPQRASEPIPQSCSSPLRKVPPR--SRQTPKAFWTEFSILRELLAQDILCDVSKPYRLATPVYASLTPQSRTRPPKDSQASPAHSAMAEEVRITASPKSTGPRPSLRPLRLEVKRDVNKPARQKREEDEEEEEEEEEEEE-KEDEEEEWGRKRPGRGLPWTKLGRKMDSSVCPVRRSRRLNPELGPWLTFTDEPLG------ALPSMCLATETHDLEEELGGLTD--SSQGQQLPLGSQIPTLESPCESGCGDTDEDPSCPRPPSRDSPRCLMLALSQSDP-LGKKSFEESLTVELCGTAGLTPPTTPPYKPMEEDPFKQDTKHSPGQDTAPSLPSPETLQLTATPGASHKLPKRHPERSELLSHLQHATTQPVSQAGQKRPFSCSFGDHDYCQVIRPEAALQRKVLRSWEPIKVHLEDLAHQGATLPVETKTPRREADQNCDP--TPKDSMQLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLLEEEEEE--GGEEDDEGEDSGVSPPCSDHCPYQSPPSKASRQLCSRSRSSSGSSSCSSWSPATRKNFRLESRGPCSDGTPSARHAKKRREKAIGEGRVVYIRNLSGDMSSRELKKRFEVFGEIVECQVLRRSKRGQKHGFITFRCSEHAALSVRNGATLRKRNEPSFHLSYGGLRHFRWPRYTDYDPTSEESLPSSGKSKYEAMDFDSLLKEAQQSLH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHJ7-1", "uniprot_id": "PRGC2_MOUSE", "id": "Q8VHJ7-1", "name": "Peroxisome proliferator-activated receptor gamma coactivator 1-beta", "aln": "MAGNDCGALLDEELSSFFLNYLSDTQGGDSGEE-----QLCADLPELDLSQLDASDFDSATCFGELQWCPETSETEPSQYSPDDSELFQIDSENEALLAALTKTLDDIPEDDVG-LAAFPELDEGDTPSCTPASPAPLSAPPSPTLERLLSPASDVDELSLLQKLLLATSSPTASSDALKDGATWSQTS--LSSRSQRPCVKVDG--TQDKKTPTLRAQSRPCTELHKHLTSVLPCPRVKACSPTPHPSPRLLSKEEEEEVGEDCPSPWPTPASPQDSLAQDTASPDSAQPPEE-DVRAMVQLIRYMHTYCLPQRKLPQRAPEPIPQACSSLSRQVQPR--SRHPPKAFWTEFSILRELLAQDILCDVSKPYRLAIPVYASLTPQSRPRPPKDSQASPAHSAMAEEVRITASPKSTGPRPSLRPLRLEVKRDVNKPTRQKREEDEEEEEEEEEEEEEKEEEEEEWGRKRPGRGLPWTKLGRKMDSSVCPVRRSRRLNPELGPWLTFTDEPLG------ALPSMCLDTETHNLEEDLGSLTD--SSQGRQLPQGSQIPALESPCESGCGDTDEDPSCPQPTSRDSSRCLMLALSQSDS-LGKKSFEESLTVELCGTAGLTPPTTPPYKPMEEDPFKPDTKLSPGQDTAPSLPSPEALPLTATPGASHKLPKRHPERSELLSHLQHATTQPVSQAGQKRPFSCSFGDHDYCQVLRPEAALQRKVLRSWEPIGVHLEDLAQQGAPLPTETKAPRREANQNCDP--THKDSMQLRDHEIRASLTKHFGLLETALEGEDLASCKSPEYDTVFEDSSSSSGESSFLLEEEEEEEEGGEEDDEGEDSGVSPPCSDHCPYQSPPSKASRQLCSRSRSSSGSSSCSSWSPATRKNFRRESRGPCSDGTPSVRHARKRREKAIGEGRVVYIRNLSSDMSSRELKKRFEVFGEIVECQVLTRSKRGQKHGFITFRCSEHAALSVRNGATLRKRNEPSFHLSYGGLRHFRWPRYTDYDPTSEESLPSSGKSKYEAMDFDSLLKEAQQSLH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YN6-1", "uniprot_id": "PRGC2_HUMAN", "id": "Q86YN6-1", "name": "Peroxisome proliferator-activated receptor gamma coactivator 1-beta", "aln": "MAGNDCGALLDEELSSFFLNYLADTQGGGSGEE-----QLYADFPELDLSQLDASDFDSATCFGELQWCPENSETEPNQYSPDDSELFQIDSENEALLAELTKTLDDIPEDDVG-LAAFPALDGGDALSCTSASPAPSSAPPSPAPEKPSAPAPEVDELSLLQKLLLATSYPTSSSDTQKEGTAWRQAG--LRSKSQRPCVKADS--TQDKKAPMMQSQSRSCTELHKHLTSAQCCLQDRGLQPPCLQSPRLPAKEDKE-PGEDCPSPQPAPASPRDSLALGRADPG-APVSQE-DMQAMVQLIRYMHTYCLPQRKLPPQTPEPLPKACSNPSQQVRSRPWSRHHSKASWAEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASPKSTGPRPSLRPLRLEVKREVRRPARLQQQEEEDEEEEEEEEEEEKEEEEE-WGRKRPGRGLPWTKLGRKLESSVCPVRRSRRLNPELGPWLTFADEPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQQLLRGPQIPALESPCESGCGDMDEDPSCPQLPPRDSPRCLMLALSQSDPTFGKKSFEQTLTVELCGTAGLTPPTTPPYKPTEEDPFKPDIKHSLGKEIALSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRHATAQPASQAGQKRPFSCSFGDHDYCQVLRPEGVLQRKVLRSWEPSGVHLEDWPQQGAPW-AEAQAPGREEDRSCDAGAPPKDSTLLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLPEEEEEEGEEEEEDDEEEDSGVSPTCSDHCPYQSPPSKANRQLCSRSRSSSGSSPCHSWSPATRRNFRCESRGPCSDRTPSIRHARKRREKAIGEGRVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNRRGEKYGFITYRCSEHAALSLTKGAALRKRNEPSFQLSYGGLRHFCWPRYTDYDSNSEEALPASGKSKYEAMDFDSLLKEAQQSLH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AP47-1", "uniprot_id": "A0A8M3AP47_DANRE", "id": "A0A8M3AP47-1", "name": "", "aln": "--MADCASLLDEELSSFVFNYLTENSGSQYGEEEVCSDRLDADFPDFDLSQLDASDFDSVNCLSELHWCNEQSDHSPASIQYSAGDPELFEEENAALLAALTDSLDGIVEDGVGGLSVFPSLGDEPEEGEEEEDDLPMESEPLPG-----SMSPETEDPSLLKKLLLTPPNVPVGLESHKDSGVHRHSSRNQHVKPVRPVLKKDKSSTQERKPRPVRPSGRLCTELHRHLTTARDN----------EDTPSADTEEEEEEEDSESEEEEEEESSSSEGESVVCIEPAKPQFSSEKELHSVVELIKYMHTYCLPVRKQASWDRK--------------------------------EREALARKAKPEHSQIPRPPPTSQKPASQTRPRMPFCRRREIKAHSLLKELLEAVSSFDVSKPYRMHSPPYIHSRGAAIRPAVDVSSSPPRQPKAEPKDSDCESWQKAAKRPKSPEPEEGSFSVRRSRRLASFPSRFAKRVRVNCG------------------------RTEQCSEEEITVKHPPTDTESSQKSSSYKPSETHNNPCCS-----DEKRSCLCLP--------LATKSNGDTQYANKPFEQTLCMELCGTAGLTPPTTPPHKPVEDELFKPDAKADLSTKSSCLMRAN---------------MRKLPEQTELYAQLRRMG--QTGDIDSKGGTQRAYGDHDYCLMGLGESRKTTAVLN---------------GSQCHVEVKEKDEEEE------------------------------MEMDVEKEEME---EKEEERVLTDCQQRTEVNSLVELPSPEE------------------TSEHSPVRSP---------SPELDAQSPVSCSPPSPSCKLSFSDESSETCHGANEKRSKTKCGQENDGNKCQVIYIHNLPSSVTQTMLRKRFEAFGHPEDCKVVIK--KEERCGVITLRHTQ-------NGQTSRHRWDLLGPSGGNGSRRFGRKRYIDLDEAG----PGPVKSKYDALDFDALLKEAQRSLHR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.:*********.:***::..*. *** :* **:*::************..*:.**:** * *: .* . . . .: ::.** **** **.:**.* **.** *:.** *. . . * . * * : .:.:: ***:****:.. . . :: *:. . ::. :. ** :* * **::*. ::...* *****:***:. :* ::*::* ..:. . :*. :. . .* . ..: :::::*:**:******** ** . : ** **:. : *: * . . . : * : .:. * :. .:* . : * * :. : . :*: .. : : * ::.: :. :: * * .: *. : * * ::*:. : * .: . *. . : ..:: : :.** * **. ** . : : *:.*. .:*.**::* :***************:** *:: ** * * . . . : : : :: **::** ::*:: ..: ..* . ::****** : *. **. *: .*.: .* : :* :* *:: . * : *: *... : .*:: . ** *:*.* :** * . .:... .* . **: : .* ** .* . . . ::: :*: .: :*:**:**...::. *::***.**. :*:*: : : :: *.** * :: :* : *:* : . .* *:* ** * * . *.. ****:*:***:******:*** ", "identical_positions": 248, "similar_positions": 283, "identity": "23.87%" }, { "cls_id": "homologset.agr.MGI:2444945", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGN6-1", "uniprot_id": "D3ZGN6_RAT", "id": "D3ZGN6-1", "name": "Group 3 secretory phospholipase A2", "aln": "MGVLGILLGVLAFLGVVPEGSHTLHWDSTSCHLVRSISGSPLGSLSFLGEDAQGLALFQALWDAHHRLQVCIRQDESELIAAFRALCAH---------EPLRHAFIHTPGPELQRALATLQSQWEACRRSEASPTGAREKRETEHRGAPAGEHQRRRRGWTIPGTLWCGVGNSAE-NASELGMFHGPDFCCREHDQCPQTISPLQYNYGIRN-FRFHTISHCDCDARFQQCLRSQGDSIADIMGVAFFNVLEIPCFVLKEQETCVAWHWWGGCRTYGSLPLAHLQPRTYYNASWKAEATPLTPS--------PQSPAPS--------WKRGPQQTPARHHSTTTVTPLQTPAISSRPDMMIPRGQPGVSHPGLQDGPKRQGAHRVCRSLR-HLDQCEHQIKPQETKFHLLNSAQTPLFHCNCTRRLARFLR---HHSLPANTNKVWELLGTTCFKLAPQLNCPEGKGCSRDHRAIKVSARHLQRLHQNGLHFWDKGTGEVLAQPLEPPGTLMSFYSQCLQLTQAIWRPGGQKKFWSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZT7-1", "uniprot_id": "PA2G3_MOUSE", "id": "Q8BZT7-1", "name": "Group 3 secretory phospholipase A2", "aln": "MGVLGVLLGVLAFL----EGSHTRHWDSTSCHLVQPIPGNPLGSLSFLGKDAQGLALFQAFWDTHHRLQVCIRQDESELITAFRALCAH---------EPLQHSFIQTPGPALQRALATLQSQWEACQRSQDSPTGAREKRAIEQSGAPDREHRRRRRGWTIPGTLWCGVGNSAE-NASELGVFHGPDLCCREHDQCPQTISPLQYNYGIRN-FRFHTISHCDCDARFQQCLRSQGDSISDIMGVAFFNVLEIPCFVLKEQEACVAWNWWGGCRAYGSTPLAHLRPRTYYNASWKAEATSYTPS--------PQSPAPSK-----HPQKRGPQQTQARRHSTTTTTPFQTPAISSRPD-MIPRGQPGVPHLGFQDGPKHQSAHRVCRSLR-HLDQCEHQIKPQETKFHLLNSAQMPLFHCDCTRRLARFLR---LHSPPAGTDKVWDLLGTTCFKLAPQLDCAEGKGCSRDHRAIKVSARHLQRLHKSRLHFRDKGTGGALAQPVEPPGSTMSFYSQCLQVTQAIWRRRGQKKFWSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZ20-1", "uniprot_id": "PA2G3_HUMAN", "id": "Q9NZ20-1", "name": "Group 3 secretory phospholipase A2", "aln": "MGVQAGLFGMLGFLGVALGGSPALRWYRTSCHLTKAVPGNPLGYLSFLAKDAQGLALIHARWDAHRRLQSCSWEDEPELTAAYGALCAH---------ETAWGSFIHTPGPELQRALATLQSQWEACRALEESPAGARKKRAAGQSGVPGGGHQREKRGWTMPGTLWCGVGDSAG-NSSELGVFQGPDLCCREHDRCPQNISPLQYNYGIRN-YRFHTISHCDCDTRFQQCLQNQHDSISDIVGVAFFNVLEIPCFVLEEQEACVAWYWWGGCRMYGTVPLARLQPRTFYNASWSSRATSPTPS--------SRSPAPPKPRQKQHLRKGPPHQKGSKRPSKANTTALQDPMVSPRLD-VAPTGLQGP-----QGGLKPQGARWVCRSFRRHLDQCEHQIGPREIEFQLLNSAQEPLFHCNCTRRLARFLR---LHSPPEVTNMLWELLGTTCFKLAPPLDCVEGKNCSRDPRAIRVSARHLRRLQQRRHQLQDKGTDERQPWPSEPLRGPMSFYNQCLQLTQAARRPDRQQKSWSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W3I8-1", "uniprot_id": "Q9W3I8_DROME", "id": "Q9W3I8-1", "name": "phospholipase A2", "aln": "---------------------MWIANERTICALMPLVILATWQLCLLPGTDAKHLAIR-----------------------------------------------LRDPQSEIESETVPLAHVHSHSHTDESGVRGAAAVHRRER--------RQLSDWLIAPNTRWCGRGNLANGTYNDLGGASKADKCCRKHDHCKMWIDGMSNRYDLFN-YRPYTLSHCSCDLRFRTCLKMAGDEDANAIGKLFFNVVQTQCFGLKAETVCVQRGGSG--KETDPCLKEEVRHKAFLRDNKRF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1N801-1", "uniprot_id": "A0A8M1N801_DANRE", "id": "A0A8M1N801-1", "name": "phospholipase A2", "aln": "--MLSNFLQIVSIFMLFHGCFSTNDMNSDTYCIWTRSVSGGRTQYAFLQRTQTSLILYDSIWKQNNRLFSCVKSNEQSIIDSYMSRCLEDSSFSQLLDERFDISVLTEADGPCEVAGVTEEFAASVRRARDLMSVEPDGFVEQDSDVSSIKTLQRSKRAWMIPGTLWCGSGNKAT-GWTDLGVFEETDKCCREHDHCKHTIPSFSYDHGVFN-TNLFTLSHCDCDNRFRRCLLGVNNSMSNLVGYGFFNVLKMSCFEFSQRTQCAKRTWWGRCVMSELAQYAVVKDAANYTDTLPEQEMESLETSFQQAITIGQNQVTKNMEESLIIQSKDSRNGTEALSPVSTSPGPSVTTLLPRKSEASVVPTYTPKTTLAQNKPDSPQGEFEMCNLYKDLDSCHLQIPALQEKFGLLNPDRRTLYHCNCTARLVQKIVSKELDETDPVHSLLMDFVSQSCFSLPKFEDCLNGQSCS----TQLIQNWRTDMAGGRHLVDFKRKLKRMNLKRSKRKDSPVRLYKKCIRMHTKLHRPRVPERKRS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6XPX3-1", "uniprot_id": "Q6XPX3_DROME", "id": "Q6XPX3-1", "name": "Phospholipase A2", "aln": "---------------------------------------------------------------------------------------------------------MWLLREAFFFGLLAMAWAFGDEAIFEDEDIYNQALP------------PVPHTGITVPGTKWCGPGNTAA-NFEDLGRERETDKCCRAHDHCDEIIESHGALHGLPTNTDWFPILKCTCEQQFINCLQAVNSITAKTLGRIYYGSRSRCFANGHPTTGCKQYQEGTFRKRCIRYQVDKSKAKVWQFYDMPFFTIPASAG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4I0-1", "uniprot_id": "Q9W4I0_DROME", "id": "Q9W4I0-1", "name": "Phospholipase A2", "aln": "-----------------MREPLPVAVVTLLLFLWLGSAMPPTSGSAVLISDMTMSVMVELS-------------------------------------SRHPFCKMHTDRGDIQRMLLQSDPRRIRQVPRESVMELEEVCRRQGSYG----HEFRGGLGFIYPGTKWCGPGTAAT-SYDDLGAHAREDRCCREHDMCPDVLNVGECRRGLCN-RGTFTRSHCDCDARFRRCLQAANTETANTLGAIFYNVVQVTCFQERSPCSAHQR-FEDFYYRTDHCPAEFRQADLYVPPHGDNLIAKILAHP----------------------QGRALAAPSWTIPAKSTARRWGVKLASVGLAAVNILREVVQRPRLLWDSLQAPVSRELPPPQRYHDPGYHYERPGPGSSYGYGQYSGRGYGGFDSPWS----------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *.* *** * * :** * *** ** * : .: . .. :* *: :* ** :. :* ::. . . : ", "identical_positions": 22, "similar_positions": 22, "identity": "4.1%" }, { "cls_id": "homologset.agr.MGI:2444946", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BH01-1", "uniprot_id": "SL9D1_MOUSE", "id": "Q8BH01-1", "name": "Solute carrier family 9 member D1", "aln": "MKVLDQSLLWMLLPFFHLIASAAEHEEVAKHAIKLHRGKGATATQRKQWALDSCRRLTGLLRQKNVVLNKLKNAIRAVEKDTSLSGEEKLFQVHTFEIFQKELNESENSIFQAIYGLQRALQGDYRDVVNMKESSKQRLEALREAAIKEETEYVELLAAEKHQVEALKNMQHQNKSLSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEASSKQNMTKREVEDGLGLSMLIDSQNNQYILTKPRDSTIPRADHHFIKDIVTIGMLSLPCGWLCTAIGLPTMFGYIICGVLLGPSGLNSIKSIVQVETLGEFGVFFTLFLVGLEFSPEKLRKVWRISLQGPCYMTLLMIAFGLWWGHLLRIRPTQSVFISTCLSLSSTPLVSRFLVGSARGDKEAGDIDYSTVLLGMLVMQDVQLGLFIAVMPTLIQAGAGASSSVVMEVLRILFLIGQILFSLAAVFLLCLVMKTYLIGPYYRKLHLESKGNKEILVLGVSAFTFLMLTVTELLDVSMELGCFLAGALVSSQGHMVTEEIMTYIEPIRDFLAIIFFASIGLHVFPTFVIYELTVLVFLTLSVVIMKFVLAVLVLSLILPRSSQYIKWIVSAGLAQVSEFSFVLGSRARRAGILSREVYLLILSVTTLSLLLAPVLWKAAITKCVPRPERRSSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LT19-1", "uniprot_id": "A0ABK0LT19_RAT", "id": "A0ABK0LT19-1", "name": "", "aln": "MKALDPSLLCLLLPFFHLIASAAEHEEVAKHAIKLHRGKGATATQRRQWALDSCRRLTGLLRQKNVVLNKLKNAIRAVEKDASLSGEEKLFQVHTFEIFQKELNESENSVFQAIYGLQRALQGDYRDVVNMKESSKQRLEALREAAIKEETEYVELLAAEKHQVEALKNMQHQNKSLSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEASSKQNLTKREVEGGLGLSMLIDSQNNQYILTKPRDSTIPRADHHFIKDIVTIGMLSLPCGWLCTTIGLPTMFGYIICGVLLGPSGLNSIKSIVQVETLGEFGVFFTLFLVGLEFSPEKLRKVWRISLQGPCYMTLLMIAFGLWWGHLLRIRPTQSVFISTCLSLSSTPLVSRFLVGSARGDKEAGDLDYSTVLLGMLVMQDVQLGLFIAVMPTLIQASASTSSSVVMEVLRILFLIGQILFSLAAVFLLCLVMKTYLIGPYYRKLHLESKGNKEILILGVSAFTFLMLTVTELLDVSMELGCFLAGALVSSQGHIVTEEIMGYIEPIRDFLAIIFFASIGLHVFPTFVIYELTVLVFLTLSVVIMKFVLAVLVLSLILPRSSQYIKWIVSAGLAQVSEFSFVLGSRARRAGIISREVYLLILSVTTLSLLLAPVLWKAAITKCVPRPERRSSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UWJ1-1", "uniprot_id": "SL9D1_HUMAN", "id": "Q6UWJ1-1", "name": "Solute carrier family 9 member D1", "aln": "MKVLGRSFFWVLFPVLPWAVQAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDDLGLSMLIDSQNNQYILTKPRDSTIPRADHHFIKDIVTIGMLSLPCGWLCTAIGLPTMFGYIICGVLLGPSGLNSIKSIVQVETLGEFGVFFTLFLVGLEFSPEKLRKVWKISLQGPCYMTLLMIAFGLLWGHLLRIKPTQSVFISTCLSLSSTPLVSRFLMGSARGDKE-GDIDYSTVLLGMLVTQDVQLGLFMAVMPTLIQAGASASSSIVVEVLRILVLIGQILFSLAAVFLLCLVIKKYLIGPYYRKLHMESKGNKEILILGISAFIFLMLTVTELLDVSMELGCFLAGALVSSQGPVVTEEIATSIEPIRDFLAIVFFASIGLHVFPTFVAYELTVLVFLTLSVVVMKFLLAALVLSLILPRSSQYIKWIVSAGLAQVSEFSFVLGSRARRAGVISREVYLLILSVTTLSLLLAPVLWRAAITRCVPRPERRSSL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*. *:: :*:*.: ..*.******::.******:*.:* * :**. ****:*:*******.******.** *****..**.***********************:***:***********:*********:*****************:********************:**************************************************.****:******..**************************************************:**********************************************************:****************** *******:***********************:******** **:*********** ********:*********.*.:***:*:******.******************:*.***********:*********:**:*** ***************************** :***** **********:************** **************:***:**.****************************************::***********************:****:***********", "identical_positions": 598, "similar_positions": 62, "identity": "88.2%" }, { "cls_id": "homologset.agr.MGI:2444947", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1F2-3", "uniprot_id": "MICA2_RAT", "id": "D4A1F2-3", "name": "[F-actin]-monooxygenase MICAL2", "aln": "-----------------------------------------MGENEDEKQAQASQVFENFVQATTCKGTLQAFNILTCLLDLDPLDHRNFYTQLKSKVNTWKAKALWHKLDKRGSHKEYKRGKACSNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDTFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVEIHVNVEFVRVREPPKDQENRKIGWRAEFLPADHALSNFEFDVIIGADGHRNTLEGFRRKEFRGKLAIAITANFINRNSTAEAKVEEISGVAFIFNQKFFQDLKEETGIDLENIVYYKDSTHYFVMTAKKQSLLDKGVILNDYIDTEMLLCAENVNQDNLLSYAREAADFATNYQLPSLDFAINHNGQPDVAMFDFTSMYASENAALMRERQAHQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMVKSWDQGTP-PLEVLAERESLYRLLPQTTPENINKNFEQYTLDPATRYPNLNVHCVRPHQVKHLYITKE-------MDRFPLERWGSVRRSASLSRRESDIRPN--KLLTWCQQQTKGYQHV-RVTDLTTSWRSGLALCAIIHSFRPELINFDSLNENDVVENNQLAFDVAKREFGILPVTTGKEMASTQEPDKLSMVMYLSKFYELFRGTPLRPMDSRRKNYGENADFGLGKTFFQNNYLNLTLPRKRTPRVDAQTEENDVNKRRRQGFNNLEELPAFSSRSLGSSQEY--AKESGNQNKVKYMANQLLAKFEENTRNPSALKQDCPRVSGMGKPVLCSASRPPGTSHCPKLEESTPRLPPPLKRQFSSTVATGQVLRELN-QVPASGECPGRPWR-----ARAKSDLQLGGAENLATLPPTCQG------ALALSGVLRRLQQVEEKVLQKRAQNLANREFHTKNIKEKAAHLASMFGHG-DLPQDKLLSKRVPHAHPP------SPPSCLPSPDPAAAPSPPAADSVSPARKV--------------------LTVGKVSSGIGAAAEVLVNLYLNDHRPKT----------QATSPDLESLRKAEFPLSLGGRDTCYFCKKRVYVMERLSAEGHFFHRECFRCSVCAAILRVAAYAFDCD--EGKFYCKLHFAHCKTSSKQRKRRAELNQQREEEGTWPEQEAAR-----------------------------RDVPAESSCAVAAISTPEGSPPDEPISPKKSKSVPKPNSRPMEVEATSPRPSEWTSVRIGPGQD--GQDVLAVRVLVTSEDSSSDTESD---------------------------------------------------------------------------------------------------------------SGSIIGPCTEACEERPRLPESPPLSQPLTRHISLRETLTQPVSLLLHHKEPQAVPGLQRAY---------------------------SLQS--PSKYQNWRRKFQSNSTPMNQRALSPPKEPPPS----SSSSSPSLPSSFSSASVPGHTTDDSSSPQVTYNLHSPQISRDDVSP-TPIYLRRARAQGITKEIPLYLPHSPMLESTEHCLVSPDGEELRSPEEISASDGCQKALALGNSESTHKDSYPVSGKDPYLPNQMLALGAAGNTGDLSEESRMGQTGGAELSKERKLGLKKLVLTEEQKTMLLDWNDYTQE---HKAGERLAQEKAENGRGN-SLKPICSSTLSQAVKEKLLSQKKALGETRTPAAKAPREREVPPPKSPLRLIANAIFR---SLLPSSEAGKKTSSKPETKTLPRGQPHAFTRSFSFRKLGSSKDGDQQSPGRHMAKKASAFFSLASPTSK------------AAQASDLSPPNPILRSRSLPNRPSKMFFATTSLPPSSKVEDVPTLLEKVSLQD----AAQGPKKGASHISPLGLKDKSFESFLQECKERKDIGDFFNSPKEKGPPGNRVPSLEKLVQPVDSTSMGQVAHPSSTGQDAQAAVRTQAGKEGSSLVSSLVLVSGPGAPVTEDTSSPTSSSAEEDVETQLSSRLKEK-IPRRRRKLE---KQMAKQEELKRLHKAQAIQRQLEEVEERQRTSEIQGVRLEKVLRGETADSGTQDEAQLLQEWFKLVLEK-----------NKLMRYESELLIMAQELELEDHQSRLEQKLRQKMLKDEGQKDENDLKEEQEIFEEMMQVIEQRNKLVDSLEEQRIKERTQDQHFENFVLSRGCQLSRT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BML1-4", "uniprot_id": "MICA2_MOUSE", "id": "Q8BML1-4", "name": "[F-actin]-monooxygenase MICAL2", "aln": "-----------------------------------------MGENEDEKQAQASQVFENFVQATTCKGTLQAFNILTCLLDLDPLDHRNFYSQLKSKVNTWKAKALWHKLDKRGSHKEYKRGKACSNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDTFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVEVHVNVEFVRVLEPPEDQENQKVGWRAEFLPADHALSDFEFDVIIGADGHRNTLEGFRRKEFRGKLAIAITANFINRNSTAEAKVEEISGVAFIFNQKFFQDLKEETGIDLENIVYYKDSTHYFVMTAKKQSLLDKGVILNDYIDTEMLLCSENVNQDNLLSYAREAADFATNYQLPSLDFAINHNGQPDVAMFDFTSMYASENAALMRERQAHQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMVKSWDQGTP-PLEVLAERESLYRLLPQTTPENINKNFEQYTLDPATRYPNLNLHCVRPHQVKHLYITKE-------MDRFPLERWGSVRRSVSLSRRESDIRPN--KLLTWCQQQTKGYQHV-RVTDLTTSWRSGLALCAIIHSFRPELINFDSLNEDDAVENNQLAFDVAKREFGILPVTTGKEMASTQEPDKLSMVMYLSKFYELFRGTPLRPMDSWRKNYGENADFGLGKTFIQNNYLNLTLPRKRTPRVDTQTEENDMNKRRRQGFNHLEELPSFSSRSLGSSQEY--AKESGSQNKVKHMANQLLAKFEENTRNPSVVKQDCRRVSGIGKPVLCSASRPPGTSCCPKLEESTPRLPPPLKRQFSSTVATGQVLRELN-QVPASGECPSRPWR-----ARAKSDLQLGGVENLATLPRTCQG------ALALSGVLRRLQQVEEKVLQKRAQNLANREFHTKNIKEKAAHLASMFGHG-DLPQDKLLSKRVPHAHPP------SPPSCLPSPHPAAASSPPAADSVSPARKVVA--------LNHRLPPPLHLTVGKVSSGIGAAAEVLVNLYLNDHRPKT----------QATSPDLESPRK-AFPLSLGGRDTCYFCKKRVYMIERLSAEGHFFHQECFRCSVCSATLRLAAYAFDCD--EGKFYCKPHFVHCKTSSKQRKRRAELNQQREEEGTWQEQEAPR-----------------------------RDVPTESSCAVAAISTPEGSPPDEPISPKKPKSVPEPNPRDVEAEATSPRPSEWTSVRISPGEDTVRQDVLAVRVLVTSEDSSSDTESD---------------------------------------------------------------------------------------------------------------YGSITAPCAGAYEERPQLPESPPLSKPLTRHISLRENLTQPVSLL--HEEPQALPALQRAH---------------------------SLQSPTPSKYQNWRRRFQSNSTPMNQRAPSPPKEPPPPP---SLSSSSSLPSSFSSASVPGHTADDSSSPQVTYNLHSPQISRGDVSP-TPIYLRRARAQGIVKEIPLYLPHSPMLESTEDCLVEPGRESLRSPEEISSSEGCQEARALGN---TRSIQHPILGKDQYLPNQNLALGAAGNPGDPREESRMGQPGGPELSKERKLGLKKLVLTEEQKNKLLDWSDCTQE---HKTGEQLSQESAENIRGG-SLKPTCSSTLSQAVKEKLLSQKKALGGMRTPAVKAPQEREVPPPKSPLKLIANAILR---SLLHNSEAGKKTSPKPESKTLPRGQPHA--RSFSLRKLGSSKDGDQQSPGRHMAKKASAFFSLASPTSK------------VAQASDLSLPNSILRSRSLPSRPSKMFFSTT---PHSKVEDVPTLLEKVSLQD----ATHSPKTGASHISSLGLKDKSFESFLQECKQRKDIGDFFNSPKEEGPPGNRVPSLEKLVQPVGSTSMGQVAHPSSTGQDAR---KLEGGEGGSSLVSSLVLVSDPVAPVTEATSSPTSSSAEEEADSQLSLRIKEK-ILRRRRKLE---KQSAKQEELKRLHKAQAIQRQLEEVEERQRTLAIQGVKLEKVLRGEAADSGTQDEAQLLQEWFKLVLEK-----------NKLMRYESELLIMAQELELEDHQSRLEQKLRQKMLKDEGQKDENDLKEEQEIFEEMMQVIEQRNKLVDSLEEQRVKERTQDQHFENFVLSRGCQLSRT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94851-7", "uniprot_id": "MICA2_HUMAN", "id": "O94851-7", "name": "[F-actin]-monooxygenase MICAL2", "aln": "-----------------------------------------MGENEDEKQAQAGQVFENFVQASTCKGTLQAFNILTRHLDLDPLDHRNFYSKLKSKVTTWKAKALWYKLDKRGSHKEYKRGKSCTNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDSFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVEIHVNVEFVKVLEPPEDQENQKIGWRAEFLPTDHSLSEFEFDVIIGADGRRNTLEGFRRKEFRGKLAIAITANFINRNSTAEAKVEEISGVAFIFNQKFFQDLKEETGIDLENIVYYKDCTHYFVMTAKKQSLLDKGVIINDYIDTEMLLCAENVNQDNLLSYAREAADFATNYQLPSLDFAMNHYGQPDVAMFDFTCMYASENAALVRERQAHQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMVKSWNQGTP-PLELLAERESLYRLLPQTTPENINKNFEQYTLDPGTRYPNLNSHCVRPHQVKHLYITKE-------LEHYPLERLGSVRRSVNLSRKESDIRPS--KLLTWCQQQTEGYQHV-NVTDLTTSWRSGLALCAIIHRFRPELINFDSLNEDDAVENNQLAFDVAEREFGIPPVTTGKEMASAQEPDKLSMVMYLSKFYELFRGTPLRPVDSWRKNYGENADLSLAKSSISNNYLNLTFPRKRTPRVDGQTGENDMNKRRRKGFTNLDEPSNFSSRSLGSNQECGSSKEGGNQNKVKSMANQLLAKFEESTRNPSLMKQE-RRVSGIGKPVLCSSSGPPVHSCCPKPEEATPSPSPPLKRQFPSVVVTGHVLRELK-QVSAGSECLSRPWR-----ARAKSDLQLGGTENFATLPSTRPR------AQALSGVLWRLQQVEEKILQKRAQNLANREFHTKNIKEKAAHLASMFGHG-DFPQNKLLSKGLSHTHPP------SPPSRLPSPDPAASSSPSTVDSASPARKEKKSPSGFHFHPSHLRTVHPQLTVGKVSSGIGAAAEVLVNLYMNDHRPKA----------QATSPDLESMRK-SFPLNLGGSDTCYFCKKRVYVMERLSAEGHFFHRECFRCSICATTLRLAAYTFDCD--EGKFYCKPHFIHCKTNSKQRKRRAELKQQREEEATWQEQEAPR-----------------------------RDTPTESSCAVAAIGTLEGSPPDEPTSPKRPKSISEPQHSDAEGDAASPLPSEWTSVRISPGEEAAGQDVLAVRVLVTSEDSSSDTESD---------------------------------------------------------------------------------------------------------------YGGSEGSHTEPCEEKPWRPGSPHLP-----HTSLGEALSRAVSPQCPEEPRAVHAALQRAN---------------------------SFQSPTPSKYQNWRREFWWSLTPVNKRTMSPPKDPSPSLPLPSSSSHSSSPPSSSSTSVSGNAPDGSSPPQMTASEPLSQVSRGHPSPPTPNFRRRAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDGLSDPAEMTSDECQPAEAPLGDIGSNHRDPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKEEEGGPVLVKEK-LGLKKLVLTQEQKTMLLDWNDSIPESVHLKAGERISQKSAENGRGGRVLKPVRPLLLPRAAGEPLPTQRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQESKTLP---AQACTRSFSLRKTNSNKDGDQHSPGR-------------------------------NQSSAFSPPDPALRTHSLPNRPSKVFPALRS-PPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNFP-----LRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGE-ADSGTQDEAQLLQEWFKLVLEK-----------NKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFESFVFSRGCQLSRT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQ90-1", "uniprot_id": "A0A8M9PQ90_DANRE", "id": "A0A8M9PQ90-1", "name": "F-actin monooxygenase", "aln": "----------------------------------------MMGEAEDEK-NRTGRLFENFVQATDCKSTLQAFNILCGSLELDPLEHSSFYGSLKSSLTCWKAKALWSKLDKRASHKEYKKGRACEGIKCLIIGGGPCGLRTAIELAFLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRALGAKKFYGKFCAGAIDHISIRQLQLMLLKIALILGVEFHVNVEFVKLAEPPEDQENEGPGWRADIRPADHPVADFDFDVVVGADGRRNSLEGFRRKEFRGKLAIAITANFTNRNTTAEAKVEEISGVAFIFNQKFFQDLRQETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIIHDYIDTEALLNSENVNQEALLVYAREAADYATHYQLPTLDYAMNHCAQPDVAMFDFTSMYASENAALVRERFGHSVLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMVKSWAQGRN-PLEVLAERESLYRLLPQTTPENIAKNFDLYTIDPGTRYPNLNSNCVRPHQVRNNYICGE-------MKLCSLERASTIRRPVNLARRESEIRPG--RLLTWCQKQTEGYRDV-NVTDLTSCWSNGLALCALIHRFRPQLIDYDSLNEQDCARNLQLAFDVAEKEFGIKPFITGKELASGQEPDKSSMSIYLSKFYELFRGTPLPPSDSKRDDDANNEKCPSGSPKSVYKSLSLQ-PRKRIPKNDKKVEDTDAISKRRRKLNYLEETTKSYNQSSSVSSEG----RELKENKVKFMATQLLAKFEDSTASCSLRRQS----DCNGERPPRPPSLDMTDSSFFNIIKKKVPPPPPPKKQFPSIALVQHSDESSDPLFLSLHSSPLNPRRKPLHPSHTHTHAQPPHTESDTESSGSRTA------VLAVTAMLQRLQRVEEEISQRKAQTQKAREFHKKSIKEKAVHLSALFSG------------------------------------------------------------------------------------------------------------------EASAPDQTD---------------------------------------------------------------------------------RSQTGLLDKQLHEE----KRESAK-----------------------------RLLQPSSSIHLP--------------SPNPLTTTSYPLTQSTATSCPPPILSSCPSFPIQ-------------------QTSSSTVHHH---------------------------------------------------------------------------------------------------------------SNSIIFHPIPECTAPIHLSFS-----------------------------------FSSAF---------------------------SLSS--KSKSE--------TCSGVNMQRQSE-----------SSSQMCDSCSSISSFTVRKQT-----------------------------------------------------------------DVPQSNEDLSAT------------------------------------------------------------KQRTVGKVSLRVG-----------------------------------------------------------------ARADALVTLYENDHRP----------------------------------------------------------------------------------------------------QTSSSGTPPSIKR--EFPQTLGDVCHACKK---------RVFVVERLSAEG-------------FHFHRECFRCETCRAPLRQG------GHCFHSEEGKLYCKLHFAQRKSLVKNGRTETLHTTCN-----------------------------------DGSHHGSSWTPESHEDHLQAESAG-----------------ILSCVKRSLCWPLHVSQTVC-----AVPRRVCTWLHG---------------------------KVSAAR-----------VHLMDNAGDYAFLYELLSVG---LPLLAILHEQLLQMYAEAEPFNLQPLQHWLEEHMG---------------------------HWVLA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1RA39-5", "uniprot_id": "MCA2B_DANRE", "id": "F1RA39-5", "name": "[F-actin]-monooxygenase mical2b", "aln": "-----------------------------------------MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKE-PLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGE-------QDLSSLERSGQTRRSVSISRRESEVRPG--RLLLWCQNQTQDYRGV-NVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYN--SINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREE------QKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHR---LTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKR----EPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIR----RVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRK-EFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQ--QGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDG---------------------------TRGQPSGGEFDSSTQQDLQTLP-----DSKEIISVSEVKDSSKKADPADSAP-ACPDSPLQK-----------------VKRSTAKGEIT---------------------------------------------------------------------------------------------------------------NKNILWKKKIRSTLPLVLMKK-----------------------------------FHRGK---------------------------PEDKTEVLAEEDGNSDFEEIHESLSSKKPSNP----------STDSNCLPTKDNSSTPLDEIP--------------------------------------------------KIPLYRTHVLPEYPKPSSSSPEPIVTSISSD--------------------------------------------------------PISFSPKKKLTLSLSEKEKLLNWDLTNPG-------------------------------KSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRK--------------------------------------------------------------------------------------SFSKGSNPVVLRRNRPMKARPLSEGSFNVG-AVFQDEERCGSLVDEGEARP------RTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNK----------------------------------ASAQQQQQQKSNSSSEDEQEPKLTHSGALQ------KKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEK-----------NKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BA1-1", "uniprot_id": "MICAL_DROME", "id": "Q86BA1-1", "name": "[F-actin]-monooxygenase Mical", "aln": "MSRQHQRHHQQHHHLPPHQQPQQQMPQQQQQLTAQQQQQQQLLMAEHAAAAEAAELFDLLCVATTMRQILALHRAMCEAVGLRPSPLNDFYPRLKAKVRSWKAQALWKKFDARAAHRVYGKGAACTGTRVLVIGAGPCGLRTAIEAQLLGAKVVVLEKRDRITRNNVLHLWPFVITDLRNLGAKKFYGKFCAGSIDHISIRQLQCMLLKVALLLGVEIHEGVSFDHAVEPSGD----GGGWRAAVTPADHPVSHYEFDVLIGADGKRNMLD-FRRKEFRGKLAIAITANFINKKTEAEAKVEEISGVAFIFNQAFFKELYGKTGIDLENIVYYKDETHYFVMTAKKHSLIDKGVIIEDMADPGELLAPANVDTQKLHDYAREAAEFSTQYQMPNLEFAVNHYGKPDVAMFDFTSMFAAEMSCRVIVRKGARLMQCLVGDSLLEPFWPTGSGCARGFLSSMDAAYAIKLWSNPQNSTLGVLAQRESIYRLLNQTTPDTLQRDISAYTVDPATRYPNLNRESVNSWQVKHLVDTDDPSILEQTFMDTHALQTPHLDTPGRRKRRSGDLLPQGATLLRWISAQLHSYQFIPELKEASDVFRNGRVLCALINRYRPDLIDYAATKDMSPVECNELSFAVLERELHIDRVMSAKQSLDLTELESRIWLNYLDQICDLFRGEIPHIKHPKMDFSDLRQKYRINHTHAQPDFSKLLATKPKAKSPMQDAVDIPTTVQRRSVLEEERAKRQRRHEQLLNIGGG----AAGAAAGVAGSGTGTTTQGQNDTPRRSKKRRQVDKTANIEERQQRLQEIEENRQERMSKRRQQRYHQTQNFYKSLQLLQAGKLLREGGEAGVAEDGTPFEDYSIFLYRQQAPVFNDRVKDLERKLLFPDRERGD-IPSALPRTADEQFSDRIKNMEQRMTGRGGLGGDKKPKDLMRAIGKIDSNDWNVREIEKKIELSKKTEIHGPKGREKVPKWSKEQFQARQHKMSKPQRQDSREAEKFKDIDQTIRN-LDKQLKEGHNLDVGERGRNKVASIAGQFGKKDEANSDEKNAGSSNATTNTNNTVIPKSSSKVALAFKKQAASEKCRFCKQTVYLMEKTTVEGLVLHRNCLKCHHCHTNLRLGGYAFDRDDPQGRFYCTQHFRLPPKPLPQRTNKARKSAAAQPASPAVPPTAGSVPTAAATSEHMDTTPPRDQVDLLETSRANASADAMSDDEANVIDEHEWSGRNFLPESNNDSQSELSSSDESDTESDSEMFEEADDSPFGAQTLQLASDWIGKQYCEDSDDSDDFYDSSEGIADDGKDDTEGEEFKKARELRRQEVRLQPLPANLPTDTETEKLKLNVDNKENMADRSSLKSGNSFESARSQPSTPLSTPTRVEMEQLERNAPRKFSSEIEAISEKLYHMNNMVKMNKDLEVLAKENLVKSDILRKLTLKEKWLAENAAIAAGQKVTPTPSATAPGLQPKSKFDEKFEKVVSPPQPVVEPKPKPVIDFNLDELKPRKPNFEERPKEQLPRPESLKKPPQQKPKGSSTNVSRSNSLKSNASNGSPKVKKAPISNNSKMQIEGILGTLRKIQSQNSSDQDEDMDVDEDVERKPNKELNSKLKEIQASSFAGTMDHIKSQLTMPTVSAQAPPSMDLSKYFPNQKQEKSSTSSTNKNQVTLKDVNLAKYFPSSPAPQRRTVETVADRLKKSQTEAALAKTKLLEDQANNQAEKTKKEVEKEGESKKITKKVADSKAVPPKRQASLDTFSLREHQMDGALDLTKKKGPTKASAGVKKPAKSGSTTSVTKATATSKGKTIKIVKKIVPKGTKAKKAAEAAQESAVVEAPPEKKPPKDEAERILDEILGDGEYRSPSSEYQRLFQDEKSPSDLSDNIDRILEESGLDVELGLPKRSSKKLVKTKSLGEGDFDMKPSKERLTGVQNILKRFESMSSVTSQNSDEQAAFKLRRMESTTSNLSSLTRSRESLVSVSDSMSDLEKTMDYLRNEWRNEATNFLQKKRDKFYAKKEEQEKESKILAKPDPLDN--LPVQYRDSKLAKFFGLAASKSPENRKSPIKKKKSPSKTPKVTKANNSLEELAKISNVRQTKKAQPKTLKPVEVKPLKPASPVPDDFEILDLLEKATEAKELERSKTKSPAVESISQTPKEAIVEISLPVEDIKNLPKTGCDKSSNSSRRGSQSSLIMSRRHSEISLNEKLNQDALAALNQIEKEREAEQVDELFQSMVEEMEQEPQPTAIVEPPEEDIDADSLCTTISKSPSAQPVTVVKRGSSEDQSIEKLFSHFSDEMLVNVEFDSNDELVGITPRATLVSRNTEDRDYLDKLESLERDEETFQPVVGEKFIQENVQDEVDGLHFPSRPQRRPKSSSSSSEPSLPVAPQRLKKKLSKLDPEDMPPSVQDLLQQVYQKNIQPELVEVIPVEGKQTLRFPSMLAEEDVDEVDHSKEGIKKIETAPEEVRKVTEPEDVARVIPSPIKPSISQSNSLKSENSSGSSLVEIPKIITPPKSSSKENSSDWDMEKLPASPMPRRRLLPNQTPYKAPSVASKESSLEWDMEKLPNSPMLPRRNKMRAISPSTNPVQLLNNLPSDVDDEAAQRRLIEDFEQERRQALIKRDENFEAIAAEQRRRDSLQSSSNSSSKRSLPPPTPPMMASRRGTTQDTNRTQDTASRHEGTPPMFKKLDVDGSGTSMDSTSCSTRRSSFAFIELQDNKPVIVPMPKKLKLPKPEPPRFVPEPVATDEPVPEVFQGRAWPKTQLEGEVDLGDSDNEDETEKLKKQLPEYARSDSPPSAAFKNRKWPDGKTVFDKRAESLEEEDIFEGLLSPRKRGSQRFMDKPRSQSPQPFKPLANSSRKSSKSFSDLKKGPSLQSLSAQSSQDTDTLSTTTTVATARPASYANYEDPMDASTQALLDRSKRLHNRKRDFVNERVVERNPYMRDVLRSTDRRDYDDVDEDLTSYRPRHYASSTLNRFPNTTIRKSNNYDYLSPSSDYLSRRSYIPSASATSSYYPSTTRSSHLSDLFRRRSPASGTVSALSGYGNKESCIGLALDRVGHLIESKCTWVRSTKVQTESESTSPDEVELNSATEISTDSEFDNDEIIRQAPKIFIDDTHLRKPTKVQIKSTMIGPNAASAGLHQKQLAAREKGGSYLQKYQPQPPLPQFKPLVQVDPTLLIGSQRAPLQNPRPGDYLLNKTASTEGIASKKSLELKKRYLLGEPANGNKIQKSGSTSVLDSRIRSFQSNISECQKLLNPSSDISAGMRTFLDRTKLGEGSQTTPGQTNELIRSATSNVINDLRVELRIQKTGSSHSTDNEKENVFVNCKNELNKGMEYTDAVNATLLDQLARKSSPTTPTNKTVVEVIDLVTPEKPIDIIDLTALETPKKQLVDGSAMDVDERLTPDSNKISELQQEVKEEPKPDVSRDVKECIPDILGHIKEGTGSKEPGGEDQQSLLEQSDEEKRDSPEKDVAEHELYEPDSVQIQVPNIPWEKSKPEVMSTTGSSGSICSSSDSSSIEDIQHYILESTTSPDTQTVGGKHNVPRLEVHDTSGALMQVDSLMIVNGKYIGDPEDVKFLDMPANVIVPPAPALKTNELDMEDDQEAEAEPVTATPEPVECTVIEAERRVTAPPPLPEMGPPKLKFDSKNENKIESLKNLPLIVESNVEHSQAVKPITLNLSNLARTPDTPTTPTAHDSDKTPTGEILSRGSDSETEHTGTGQVLTETELSDWTADDCISENFVDLEFALNSNKGTIKRRKDRRRSGASKLPSGNEVIHELARQAPVVQMDGILSAIDIDDIEFMDTGSEGSCAEAYSATNTALIQNRGYMEYIEAEPKKTTRKAAPPSSYPGNLPPLMTKRDEKLGVDYIEQGAYIMHDDAKTPVNEVAPAMTQSLTDSITLNELDDDSMIISQTQPTTTEESEALTVVTSPLDTSSPRVLDQFASMLAAGKGDSTPSSSEQQPKTSTVTSSSTGPNSSTTGNVSKEPQEEDLQIQFEYVRALQQRISQISTQRRKSSKGEAPNLQLNSSAPVIESAEDPAKPAEEPLVSMRPRTTSISGKVPEIPTLSSKLEEITKERTKQKDLIHDLVMDKLQSKKQLNAEKRLHRSRQRSLLTSGYASGSSLSPTPKLAAACSPQDSNCSSQAHYHASTAEEAPKPPAERPLQKSATSTYVSPYRTVQAPTRSADLYKPRPFSEHIDSNALAGYKLGKTASFNGGKLGDFAKPIAPARVNRGGGVATADIANISASTENLRSEARARARLKSNTELGLSPEEKMQLIRSRLHYDQNRSLKPKQLEEMPSGDLAARARKMSASKSVNDLAYMVGQQQQQQVEKDAVLQAKAADFTSDPNLASGGQEKAGKTKSGRRPKDPERRKSLIQSLSSFFQKGSGSAASSSKEQGGAVAAVHSEQSERPGTSSSGTPTISDAAGGGGGGGGVFSRFRISPKSKEKSKSCFDLRNFGFGDKDMLVCNAASPAGATSASQKNHSQEYLNTTNNSRYRKQTNTAKPKPESFSSSSPQLYIHKPHHLAAAHPSALDDQTPPPIPPLPLNYQRSDDESYANETREHKKQRAISKASRQAELKRLRIAQEIQREQEEIEVQLKDLEARGVLIEKALRGEAQNIENLDATKDNDEKLLKELLEIWRNITALKKRDEELTIRQQELQLEYRHAQLKEELNLRLSCNKLDKSSADVAAEGAILNEMLEIVAKRAALRPTASQLDLTAAGSASTSAEATGIKLTGQPHDHEESII", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. .:..:*: : *: : * . : : * * .** **: : ***:.** *:* *..*: * :* :* . : *::*.****:***** *******:**** ::*********:.* *** *************:********** :*:*:**::***.* .*.* : **. * **** . *:*:.::.::***::****:*. *: ****************** *::: ***************** ** :* :************* **********:**:*****:.* :. ** **: : * ******::.*:**:*.*::*:** .:*********.*:*:* :. : : :: .************ *:*******:::*:*: :* * : .* :*::***:**** ***.:.: :::. **:**.******* .*.. **:: : : . *:..:: * ** * . * ..*: : .:.: . : .* .***:*: **:**:: : :: . .. :*:* * ::*: * . :.*: :. **.:: ::*: . . . . . .: .: : . : :*: * .. :: ::.: : ::. . . . . . : . . : . . . : ::::: : : : *.: . :: : . : . * : . .. ..: . . : . * . . : .. : . : . .. . *. : .* : . : : . :. . .: .. : . : . . . .. . .: * * :. : . : : : . :: . . * : : . :: . : * * ", "identical_positions": 296, "similar_positions": 296, "identity": "6.25%" }, { "cls_id": "homologset.agr.MGI:2444951", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96B23-1", "uniprot_id": "ARK2N_HUMAN", "id": "Q96B23-1", "name": "Protein ARK2N", "aln": "-------MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDS-SNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETS--TMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GF24-1", "uniprot_id": "A0A8I6GF24_RAT", "id": "A0A8I6GF24-1", "name": "", "aln": "-------MKMEEAVGKVEELTESAAPPKASEQETVKEEDGSVELESQVPKDGGAGSTVLSSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDS-SNHCMLSPSSSGHLADSDTLSSVEENEPSQAETTVEGDTSGVPGATVGRKSRRSRSESETS--TMAAKKNRQSSDKQNGRVTKVKGHRSQKHKERIRLLRQKREAAARKKYSLLQDSSTSDSDLTCDSSTSSSDDEEEVSGSSKTITAEIPDGPPVVAHYDMSDTSSDPEVINVDNLLAAAVVQEHSNSVGGQDTGATWRTSELL-----EAGHLDPGFLASDKTSVGSAPLNEEINIASSDSEVEIVGVQEHARCAHPRGGVIQSVSSWKHGSGTQYVGSRPTQSWTAVTPQQTWASPAEVVDLTLDEDGRRKYLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH50-1", "uniprot_id": "ARK2N_MOUSE", "id": "Q8BH50-1", "name": "Protein ARK2N", "aln": "-------MKMEEAVGKVEELIESAAPPKASEQETAKEEDGSVELESQVQKDGVADSTVLSSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDS-SNHCMLSPSSSGHLADSDTLSSVEENEPSQAETTVEGDTSGVSGATVGRKSRRSRSESETS--TMAAKKNRQSSDKQNGRVTKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDDEVSGSSKTITAEIP-GRGCFLN--------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B7W2-1", "uniprot_id": "A0A8M2B7W2_DANRE", "id": "A0A8M2B7W2-1", "name": "", "aln": "MTDAQKANELPECPSEGGATAEEQDMPLRQETTPTSSPAGEDPISSQSPDKQAPG---LLSMPCLLKELHRDSAPGQPQETAPPPSSTQSGPQEDSDSSVCLRSPSSSGHLGDSDTLSSAEEVAAP--------------TQTAGRKSRRSHSESDTSTVAMAAKKNRCQEKQVNGRVR-VRGPRSQRQKQRMRQLRQKREAAARRKPDVLQDSSTSDSDITAHSSSSSP-LTASSDNEGETINSHAPAGHRRADTSGASARGRGQLDLGVASGSLGGVLEEALTRFAAMQR------------------------------------QTEERFRVWMDRLTRLHSDDDLSSSENPEG--RSQVSSFLPSSESQ---ETLAAYQMARLNAMTVPPPPQTAGLNGNAEPPEPNV-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *. .: *. * .* .... *. :.** .. .. : ****** **:***: .* .* . .:* :.** *. *: ********.*******.** .. *.*******:***:** :******* ...: **** *:* ***::*:*:* **********:* .:**********:*..**:**. . ....:**.:. * * ", "identical_positions": 104, "similar_positions": 64, "identity": "25.12%" }, { "cls_id": "homologset.agr.MGI:2444957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DF37-1", "uniprot_id": "B5DF37_RAT", "id": "B5DF37-1", "name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "aln": "MHSSTGAMSEREERRFVEIPRESVRLMAESTGLE-LSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEVLPLRPAREGELYFPEDREVNLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYQQVTRAVLGDDPQLMKVALQDLQTNSKIAALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLIRNPHLCLGPYVRSLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQQILLSLQKVLTDPVRPLCSHYGAVVGLHALG--WKAVERVLYPHLPTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQ----AAEPNRGGLGGRGYRPAEDLPWDSLLLQESPPGGGSEPGFGSGLLLPSGVAG-SEDPS-SLTLADIYRELYSFFGDSLATRFGTGQP----APTAP-RPPGDKKEPATTP---DSVRKMPQLTASAVVSPQGDESPCG---GTLAAAN--ATSESRP---LPRVHRARGAPRQQGPGAG-TRDVFQKSRFAP--RGAPHFRFIIAGRQAGRRCRGRLFQTAFP--APYGPSPASRYVQKLPMIGRTGRPARRWALSDYSLYLPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2K4-1", "uniprot_id": "TAF6L_MOUSE", "id": "Q8R2K4-1", "name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "aln": "-------MSEREERRFVEIPRESVRLMAESTGLE-LSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEALPLRPAREGDLYFPEDREVSLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYQQVTRAVLGDDPQLMKVALQDLQTNSKIAALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLIRNPHLCLGPYVRSLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQQILLSLQKVLTDPVRPLCSHYGAVVGLHALG--WKAVERVLYPHLPTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQ----AAEPNRGGLGGRGYRPAEDLPWDSLLLQESPPGGSSETGFGSGLPPPSGVAG-PEDPS-SLTLADIYRELYSFFGDSLATRFGTGQP----APTAP-RPPGDKKEPAAAP---DSVRKMPQLTASAVVSPQGDESPCG---GTLATAT--AASESRP---LPRVHRARGAPRQQGPGAG-TRDVFQKSRFAP--RGAPHFRFIIAGRQAGRRCRGRLFQTAFP--APYGPSPASRYVQKLPMIGRTGRPARRWALSDYSLYLPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6J9-1", "uniprot_id": "TAF6L_HUMAN", "id": "Q9Y6J9-1", "name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "aln": "-------MSEREERRFVEIPRESVRLMAESTGLE-LSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEALPMRPAREGELYFPEDREVNLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYHQVTRAVLGDDPQLMKVALQDLQTNSKIGALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLFRNPHLCLGPYVRCLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQHILLSLQKILADPVRPLCCHYGAVVGLHALG--WKAVERVLYPHLSTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQ----AAEPNRGGPGGRGCRRLDDLPWDSLLFQESSSGGGAEPSFGSGLPLPPGGAG-PEDPSLSVTLADIYRELYAFFGDSLATRFGTGQP----APTAP-RPPGDKKEPAAAP---DSVRKMPQLTASAIVSPHGDESPRGSGGGGPASASGPAASESRP---LPRVHRARGAPRQQGPGTG-TRDVFQKSRFAP--RGAPHFRFIIAGRQAGRRCRGRLFQTAFP--APYGPSPASRYVQKLPMIGRTSRPARRWALSDYSLYLPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEV1-1", "uniprot_id": "E7FEV1_DANRE", "id": "E7FEV1-1", "name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "aln": "-------MTEREERRFAEVPRESVKLMAESAGVE-LSEELAGLLAEDVCYRLREATQNSSQFMRHAKRRKLSVEDFNRALRWSNTETVCGYGAQDALPFRPLKEGELFYVEDREINLVELALATNIPKGCAETMVRVHVSYLDGKGNLEPQGTVPTAVQSLSEDLLKYYQQITRAILGEDPHLMKVALLDLQSNSKIAALLPYFVYVISGVKSVSHDLDQLNRLLHMVKSLVQNPYLYLGSYVRSLVSSVMYCILEPLAASINPLNDHWTLRDYAALLLSHIFWTHGDLVSGLYHQILLSLQKVLSDPVRPLCSHYGAVVGLHALG--WKAVERVLYPHLPAYWANLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKALSLTLAAEGGSAALSG-SVTGAVGFRENSPGLS-PPPEPLSEPPLGIASHLQAGGAGCPWEEWTPVSLPAMYCELYSFFGDSLAVRFSTDPPLAGAAPAGPSQPLEGRKETATAAPNLESTRKMPQLTASMNISPRQDGSPRTEPQPPSLAATVPGRSLARSSSSSSSVSRSRSSSSRPGRSSSQSRDIFPKARFPLPQAGPPAFSFIIGGRQMGRRCQGRRFQTSFSPTPPLTSLPPRAYAHKLPVIGRVSKPVRRWTSSHYSLHLPL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53040-1", "uniprot_id": "TAF6_YEAST", "id": "P53040-1", "name": "SAGA complex/transcription factor TFIID complex subunit TAF6", "aln": "-------MSTQQQSYTIWSPQDTVKDVAESLGLENINDDVLKALAMDVEYRILEIIEQAVKFKRHSKRDVLTTDDVSKALRVLNVEPLYGY------------------YDGSEVNKAVSFSKVNTSGGQSVYYLDEEEVDFDRLIN-EPLPQVP-RLPTFTTHWLAVEGVQPAIIQNPNLNDIRVSQPPFIRGAIVTALNDNSLQTPVTSTTASASVTDTG-----ASQHLSNVKPGQNTEVKPLVKHVLSKELQIYFNKVISTLTAKSQADEAAQHMKQAALTSLRTDSGLHQLVPYFIQFIAEQITQNLSDLQLLTTILEMIYSLLSNTSIFLDPYIHSLMPSILTLLLAKKLG-GSPKDDSPQEIHEFLERTNALRDFAASLLDYVLKKFPQAYKSLKPRVTRTLLKTFLDIN---------RVFGTYYGCLKGVSV-LEGESIRFFLGNLNNWARLVFNESGITLDNIEEH------------LNDDSNPTRTKFTKEETQILVDTVISALLVLKKD---------------------------LPDLYEGKG------------EKVTDEDKEKLLERCGVTIGFHILKRDDAKELISAIFFGE-------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ::: *:::*: :*** *:* :.::: ** ** **: * ::: :* :*:** *:.:*..:*** ..*.: ** :. *:. . .* . * : : . :* * * ** : ::: . * . : . : : ::*: : .: : ** : . .:.* .: : . . . * .. *: ** *: *: .: . : * ** :.: * ***:: : :* : : .: *. .. *. : . .. .* *:: : ..: ::* .:. .. * *. : :* .: * .: * . : . . : :. :* * : . * : .*.:* . . . .:.: : :..: : : . * : : * . : ..:. ..: : : : * * *: .:. . * ", "identical_positions": 75, "similar_positions": 168, "identity": "11.49%" }, { "cls_id": "homologset.agr.MGI:2444959", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2B9E0-1", "uniprot_id": "A0A8M2B9E0_DANRE", "id": "A0A8M2B9E0-1", "name": "Histone-lysine N-methyltransferase 2C", "aln": "MSSEEKSLEPSEQGPSPPLSSAGATPSGSPAPLDRRPRGRPRKD----ASSVTVTPKSRRKSRSRGCVQADDEDSMDATDVTPTPDIEITPEIDVVEPETDDEFPEPLDLSPRDERPLSPLFQRSVSEDSAGSSASTTRKAKTREKLCAFCYCGEKSLLGQGELKLFGPTPGYVPLHIRNRRGSSEKDDDYHDDDNDFDDNDNNRSPGHRGSGLKKVSSPDSGLHSTSAPGSTDPAAEEPGRKFWDELGQIGLPDEINVAFLFDPTGQCCAHLRCAAWSEGVCRGEGQSLLYVDKAIDSGSTECCAYCKRLGASIKCCEESCGRSFHYPCAAAAGTFQDIKTYTLLCPDHIQQALVRSKDG-VKCLVCDSSGDLLDQLFCCTCGQHYHGTCLDVTVTPLKRAGWQCPECKVCLSCKNP-GDDSKMLVCDMCDKGYHTFCLQPIMETIPTNGWRCKNCRTCAQCGMRP-----NGQWSSNGVMCEGCQQQHESALLCLICGQSQDSGSPADKHTCCTCKRWVHVDCVRQEGTNPDTQLQDGYTCRACKQVEEETRHSQPVSS-QEASLT--DPEPAEDVFMSVEEVQEAEGEVVLEPEPSASPLATLPDNFLSSTEP-----AQEIQVTVTLTEGPDPPPCSSTAVGVSSFSFQASTTTEDHIQESSLIGALEMGKESEDKLPETTEEEPEPNVSKALPALPTKETSPMHTLAQEEEPMDVYSSDP--YSMKDKRMTEAAVEDP--EQKQEHEKPEVPDPEVTSIIPEPE---SVPLIPESSP-TMEMDTTPVS--ERSFSSFSSPVEDKCLVLKHSPGLSSEGSIKLTQSPFSTEASPRGSSQNQTPTHGLNAAGFSPNVSNTTFFPLTPKIGMGKPAISKRKFSPGRPRVKQGAWINRSAMSSPSWSPERSDAWDSPKTRPMHGLPVWTMRL-GRGSGFPGRRRPRGANLSGRGGRGRSRLKMESSPVVTPGLSFLDSPYVVKEEEENSMHNTVVMFSTSDSFTLKQDMCVVCGSFGRGAEGRLLSCSQCGQCYHPFCVNIKITKVVLSKGWRCLECTVCEACGQASDPGRLLLCDDCDISYHTYCLDPPLQNVPKGSWKCKWCVLCTHCGATSPGLRCEWQNNYTQCGPCASLTVCPVCTRSYREEELILQCRQCDRWVHGSCQGLNSDEDVENAADEGFDCTLCRMHT--VPTPGAAVPKLVEISEPPMVAQILTKVKENEFQRTYTQDGVCLTESGLCQLQSLSVQTTRRKRPKPKLKLKIINQNSVAVLQTPPDAQSELFRDGDLDDSR-EGDPMDCDGKSDSSPEREHCDDHLKGVD--DSNKKRKRKPYRPGIGGFMVRQRSKAGQGKGKRSLSRKDSTSSLTENLTGRDDGWNE--PDTPVDG---APPIISEPLEKVKKRYRKKKTKLEEAFPSYLQEAFFGKELLDKSKQTKSALETGAVEEASHTDSKSQSSSFLDPLSDPLLSATSTPVSSKAGTLPNVEDPLT-ELVLHSDDDLLGMLSDDLVKPGHESGLDLCPFQVDSSPSPFAGLDIGTLPDDQSVP--PHPGPARGSRLQEEPLDVILSPELDKMVSDGAILSKLYKIPELEGKDVEDLFTAVLSPNASQPPQLPHPPNTAPNASAPAMSLQNQGGVG-GMFPRMPMMNGMMGPNTHFPPNPMIPVAG--VSGTFSSVHRMPFPEN-VREKKFSQTSGDVIGPWSSPVPVPGSVPP--PEVETDTMSNAQRSTLKWEKEETLGEMATVAPVLYTNMNFPNLQDEFPDWATRVKQIAKLWRKASSQERAPYVQKARDNRAALRINKVQLSNDTMKRQ--QQQQAVEVFDPNVS-MDTDLLFKDPLKHKESEQEQEWKFRQ------------QMRQKSKQQAKIEATQKLEQVKNEQQQLQKQ---QQQLQ-------------YSG--DASNSPHTSSGGNSPLQALTPKDSFAMTQ---------MPGTASSGTSADDVFLRPQPPPLSSTSKTPTQDTQYPQGPSSQPQSPQMFSPESSGSRPSSPYDPYGKMVGTPRPPPSGSSTPRRGSVSDMQ----------------ERCRPSSAHESFGSPTTTSTDPYAKPPDTPRPS---DPFVKPMCTPRLGSLSEQQGRQLMGNVTPGDNFSRPGQRSEAYQRMAHSRMVLSDPYSRPLLTPVPGSNESGSVPVFKTPMPPSGLQQDSFNGGQQ----------GMRRGSSDTFPHVQHTDTYSNQPLTPHPSMADGINNEGRMMRPGQGSHFAQPLSMGRHPQRDPYSQAPSTPRQDYPQQMSDPYAQMPGTPRP----------HDPYAQMPGTPRPN-CDPYPLPPPTTRTEPIDKFSQS--QPSSRRQSPSHAIDPYAQMPGTPRPSPGERYSKSPGSLRSSDPFSQPPGTPRPIKNEIYDQ-QGTPMPILPDPYSQPPGTPRPGAGLEGFSRLNPRLNFITHQTDPLGLQAQSRTQDPFSRSCGTDSQTPKHPGISDENISIQQT-IPNQTPIHDP---FEQAPLT-PCSQTGERSSQDVIVSTGNPSDS-QNTMQPPLGETE-EKIKQRQRLRQLILKQQQEK-SAIRKEKGLQEATASAAPGTPRHWSQDDSGPQSDIFGRPPPPYPGTMRSSPIHAGQRFPGTFLADQCGPMPNEPQCSRQPFPRDLNNVGMRPQGQRFAFPPG----APNQEQFLRPPHQMQGGPLVDNVPPHMRRHLSVEGVRSMGNN---HQIGLPQHFPPRGIPMQQHNIMGQQFIELCHRAPENRVRLPFGPPNVLDYPNHPQRQPHG---FTGN-MVFTGNQGPRFIEPLLGQPRQESISHLQTSANIDNLHHN------TTQQQTPLTAQVSHSVRTDSVTPAESPLHPDTTSGSTEEIPLPCRDG-VEKLETDDS-----VVKDLDDVEVKDLVDDDLDNLNLDADDGK--DLD----LETNDLHLDDLLESGKFDLIAYADPEMNLEDKKDMFNEELDLSDHIDDEHGDTSDLQKALSEKRN------ARCEGGSAQSTLEGEQGLNILKPEKT--LSNEVLDHSQSEITIKTEIQGLATSVDDHRPASSKSSQNDVSGLFEDSCEDAHCAPTLSSLMVKEKLED---------TRSESIISAIQ-GDPNSQTNLDSNMSMVM----LQGQSQEHRIKSGVTMGHRVDSALTQGTLLSNSNMMHSGNQQVPLQGFGPSQGQHIHLNMPAVGT---QQPVLINPQNQQGIFSPGIPVQQGSLMQQSQQNRPLLLEEQPLLLQDLLDQERQEQQQQRDMQAMIRQRSSDPFFPNIDFDAITDPIMKAKMVALKGINKVMVQNSMGMPPMVMN----RMQQVPASHAPDTPAFSQPFFGPDGKLPPQIARPTPPNFGPGFVNESQKKQYEEWLQETQQLLQMQQKFLEDQIGAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKNVTEQQSVVQKQLEQIRKQQKEHAELIEEYRVKQQQQQQRLQTG-----------MMGPMKTMPVMQGQPPGMMPVGPPMAQPMMGSMLPM-QHPHFG--------KPSRMPSMPGWHPG---TTGPISGPRMPPHLPPQMALPNPAQPLQAQPPAPIAPGGKPGQSGTVAGGNGGGASSSAPHVKFDDNNPFSEGFQERERRERLREQQEKQRVQLMQEVERQRALQRLELEQQSLGLGPDNNG--DSLAQMPFYNSDLSQEFMQTPRPQQ----QQQQLGPLFPQQGNVPCDFVGQGSAFMQGGEHRPIPGNGSFGPEMG------PNFQPKNP---MMPG--FSAGRPRPPGFGGTRMPHHGGGEPSSFGMNSTTPLPP---NFPGSGQSLIQLYSNIIPEEKGKKKRSRKKKRDDDADSVKTPST---PHSDITAPLTPCVSDTSSTPTRS-VAIMGDQDTSEFSNP----LGSMTG----------LPSSELEISLS-GSTPLRRQTSVSSEAEHG-LLHDIKLEKLESSVCQKAEGEAPVGHSAEETGIIKTEEVNEIISHNRTSQSPAQSTKGEPGNELLKHLLKNKNTPPPPSAPLMHQMSNESLRSEDEGLNDSKGYLRQDSTDSMSGIN-SRLTDLEPSLPEQCK-------KKQRNKRTPKNGVDKPPSRWKKRKKDEDERQAIYTNTDTLMTQLKQQ-LSMLPLMEPLIGVNFAHFPPYGSGQLNGENRLSGSFGSASLDGVSDYYSQLIYKQNNLSNPPTPPASLPPTPPPVARQKLLNGFATAEELARKAEVMVSKSLGQKQLT----ASFKAEDDLLGHTITQGPKTVDVPASLPTPPHNNQEDLRGQEHCIDRDTPDSFVPSSSPESVVGMEISRYPDLSRVKEEPPSPAVSPVIPILDCK---GSEARRWEVKTEPPSNFFASQFGQLSTCLRTDLVPVSITLNPVAAMNIQGVVSALANMLCVSIPGNYEVTRSPGP-EHRSSIDMLSGLKVPHPTSLFHQQPGMRLHRPPLPHQTF-----------SDGTAMVRRDYGQMHGSSLGSKPQWCSHCRVVVLGNGVRKSTKELPMNKLGHG---GAVES-LVFCSNNCLVLYSASMQSK-LLDGKPNFPPPSESGDKQNPTKVLHQYNNNISDLDVHCLAQLQPKQSPPPTPIISFPSITSEMLRGDCKP-----DTLKVTVKLKPRPRAVHNGGDEPRYLSGKRWKALRWRRWSVQIIVPKGNYHLPVEEEIDALLKKLGTSLRPEPMPKDMRRCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRRGLSVRCAYCQQTGATSGCHRLRCTNAYHFTCALKAQCTFFKDKTMLCHLHRPRGTSLIGGGLLGTEHELRCFAVFRRVYVQRDESRQIASIIQRGEREHTFRVGSLVLHAVGQLLPQQMLAFHSMTAIFPVGYEASRIYWSMRHGNRRCHYVCSINENDGSPEFVIRVVEQGYDDLILTGSSPKGVWDKVLEPVAERRNETGFLRLFPVYLKGEDLFGLTVSAVTRIVESLPGVEACERYTFRYGRNPLMQLPLAINPSGCARSEPKACTHIKRFVLRPHTLTSTSKALQSPGNPAEIGVPPYSKHFVHSKSAQYRRMNAEWKSNVYLARSRIQGLGLYAARDIEKYTMVIEYIGTIIRSEVANRKEKMYEAQNRGVYMFRIDSEHVIDATITGGPARYINHSCAPNCITEVVALERGHKIIISSNRRIQRGEELCYDYKFDLEDDQHKIPCHCGAVNCRKWMN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3B7B2-1", "uniprot_id": "A0A8M3B7B2_DANRE", "id": "A0A8M3B7B2-1", "name": "[histone H3]-lysine(4) N-methyltransferase", "aln": "MSSEEKSLDPSDKGPSPPPCSSGATPTGSPTPTDKRPRGRPRKDALSTATSIPSVPRQRKKNRGRGKALVEDEDSTDGMETAETGSTQETVAKGQQE-ETEDASAMAVSAEGEEEEQSSSPLP-ASSKTGAAQTSSASGEAKSSEQLCAFCYCGGRSLLGQGDLKPFRVTPGYDPP---PRQSSTEEVHDHSDKTG-------AASQSGRQRGLESVG------------------AEEAGSRFWDELRHVGLPDDVDVQTFFE-SGQCWAHQSCALWSNFVCQAEDQSLLYVDKAIHSGSTEHCAYCKRLGASIKCCEEGCDRSYHYPCVGAAGTFQDFRRRSVLCTEHIELAISKYEEE-ANCILCDSPGDLLDQFFCTSCGLHYHGMCLDISVTPLKRAGWQCPECKVCQTCKEP-GEDTKMLVCDVCDKGYHTFCLKPAMDSIPTNGWRCKNCRMCVQCGTRS-----SEQWHHNSLLCQNCGDQQDTTLSCLCPSN-VVPDIQKDLLSCHQCKRWFNPECERPSEGHTHPQPKEDHICSTCRTTGIESGHVCTEADGVQAEIQ--SDVGAEESTQLVPSNNDSEPAKVQDIEPHQPVREMQNEEKQTTNEKQMMEIGADVGGDLTKPESSETSHHSAEKEMTSDASPRETKGPEGEQTEQKLDFAPETSTVQQLETFFKTEEPPETSASLKENISKNENGSKPCLEEKKINPSPTKEPAPACTSHEEEPMEVLFTEEPSAEAHGVTVEPEVNTSENTPLIQSQRKIVQEQIIPPEIH-TKEMDDITVDGDHRCLAKLTSLVEES-TSLQQPPHRQPEGLLLVVQG----------TSQPQALTQAVSRESIS-NVPSSAFIPITPKIGMGKPAISKRKFSPGRPRVKQGAWNRR--PSSPSWSLDPTEGWDGLKSRQPHSTAAWIFRVQGRGSGFPGRRRPRGSGVTGRGGRGRARMKNGVPPIPTPGVHIMEPMLTFKEEEETAMHSTVVIFSSADTFTMKQDMCVVCGSFGQGVEGRLIACAQCGQCYHPYCVNIKITKVVLSKGWRCLECTVCEACGQASDPGRLLLCDDCDISYHTYCLDPPLQNVPNGSWKCKWCVSCTQCGATSAGLRCEWQNNYTQCAPCASLASCPLCQQEYKEEEIILQCRQCDRWMHASCQGIHSEEEVEKVADTSFDCNLCQGHIPLSPAPGTPSKSSLDFADSVFMPQRVTKTRDHDLMRTYTQDGVCLTESGLSQLQSLANAASRRRRSKPKLKLKIINQNSVAVLQTPPDPQTELSRDGDLEDTKTEGEMVDGEVKSDSSPEREPTAEDDSKDT--DACKKRKRKPYRPGIGGFMVRQRNRTGPGRTKPAFVRKDSTG--SETLQGKDEGWGDQAPDTPVDEKHPLPDFPDNPEVKIRKRYRKKKTKLEEAFPTYLQEAFFGKDLLDKSKQNRQQTTRLLEDER---DRKQLLANQMKPFSDLSLNVSAALLSSKAAAQNSVEPLVDLSEELKSDTELLGMFSDNNDKQSEESGVDFCPFQVEYSPSPFG-LDIAPLAEDESVSSQAHLGRTHPRLVPEEPLDGILSPELDKMVTDESILSRLYKIPELGGKDVEDLFTAVLSPSTSQPAHMIQQIHGAQTLHGPSGPVFHPSQANSGLSSRMPVMNGLMESKQQFSQARIGPGAGPEMAQNIPPMQRIPFSDN-LRDRKFNLMSQETAGPWSATGSASSSAPAAVSEMEGDSMSTAQKSTLKWEKEETLGELATVAPVLYTNVNFPNLKEEYPDWSTRVKQIAKLWRKASSQDRAPYVQKARDNRAALRINKVQISNEPIKRQPPQPQQPLEVFDPAIPPLDPELLFKDPLKHKESEHEQEWKFRQGRKEFEIFDRIRQMRQKSKQQAKIEATQKLEQVKNEQRQQQQVPGSQSDHD-------------SSGNLKSPGSVHSNSGDMSPNQPSS-KNGVSKSQ---------LLGTSCS---PDDIFLRPHPPPQSS---------------GSQPQSPQMFSPNSSGSRPSSPWDPYTKMVGTPRPPPSSQGTPRRNSESGKS----------------PKGLP----EPIGSPTAICNDPYAKPPDTPRPAGTTDPFLKPMCPPRPS--QTLDGRHVIGSPN-HDSFSRMSVRKEAYQRMPQGRMILSDPYARPLLTPIPGSNESGSIQVFKTPMPPPQAQEQYVGMHARRVSADAFERPMMSSRSNEGFSHNQQNDPYAQPPLTPRPVVSDGFAN-QRISRQPQSLPFSQPGPMTRQPSCNSYARAPSTPRPDYSQ--CDPYVQQPGTPRPSSDPFAQSPFSNPYARMPGTPRPHDPEPYSQQSASRHPAMMNQPSQQSQQQTHNRIMSPISMDPYTQHPNTPRSGIVDPFPKSPSNQRTPDPFCQPPGLPRCVGPDLHIQSIGRSQSLRNDSCSHIPRTP--HHGVVGQVLVSGPLSSQDPFSPPQVLMQES-----FSSPTKHGPQTLKHLSMTDDSGSQPLSNRPNQTPIHDP---FEQTAMLGQCGENKDQQSLVQIISSHTMGQPGSGTQTIPLAEAE-ERLRQRQRIRELILKQQQQK-SAIRQDKVVQDHTLTMSPATPQHWNLESTGQQSEIFNHPPPPYPG---PGAVRAPQRFYAT--RDRQGQFP-EGQLPRPQFPGDADSN-TRQLGARMPLTPG----IQGPLGAIR-PHQMQDS---IEAHPQMRRSMSMDLGKSIEG----SPLGTP-HMPPRGMHVQQHNIMGQPFIELRHRTPDSRLRLSFGPPGMQGNRMESPLQQHAPGFLSGQELVFPFNQITKAVDTPLNQP-QVAFTQMQTSLSLGNLQQPNISL-RAGHTQIPLTRSISQPASNETLSSPLHTDIAAVSAVQNDEVPLPTNEVPEEKIDTVES-----AVKELEDVEVKDLVDADLENLNLDPDDGK--DLD----LETNDLHLDDFLKSGKFDIIAYTDADLDLS-------EDLDLSDTMEDNTEISEKKAEKKTESFN------ATSSASCSTSAVTEAVDKTALSQDD----TNQEIPQDQVLVSLKKEDDNKNGFKDCLSQDSSCSNQISDS---AANNQASFKRDVESSLQVHPDTTP---------VLSSMLVSVPPEGKELKQEQCGKSTEQNN----LSNQETAMSLSN-TMLGQENFSVQGIDTGLNIDQSLVSSHDESALEVSSSIQ-EQQQSHIFGIDQ---KDAVLSGEQNS-------ILTQQAVLSQQGHQNRPLLLEEQPLLLQDLLDQERQEQQQQKQMQAMIRQRSSDSFFPNIDFDAITDPIMKAKMVALKGINKMMVQNNMGMSPMVIN----NAQTGQALPDTDGNITPMQLPGQDSKLAPHIARPNPPNFGTGFAHDTQKAQYEDWLRETQQLLQMQQKFLEEQIGAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQQGVVQKQLEQIRKQQKEHAELIEEYRVKQQQQG-ALQP-----------------PIMPGMQP-PAGMMQVGPPINQSMVGPMMPIRLHSNQP--------DVTKMPNTAGWHPG---APVPT-GPRMPGVMPAQVVQPQPLQPAAARPTQVQAGG-------------------ESPHVNFDDTNPFSEGFQERERKERLREQQERQRMQIIKEVERQHVKHCVEQQQVSN--CQDGTM--RGLSQMPFYNQELPQDFMQPPRLQQ----QIQ--GPTFPQQQGTQQGYIG--------GPPRPLLGNGPFPQEMG------SGFAPQNL---AVHGPNLIQAQTRPQRYSVPHMMAQNPPQGHPFPMEGPTPLPP---NFPGPGPSLIQLYSNIIPEEKGKKKRNQKKKKDEDCESLRAPSTPHTPHSDMTAPLTPCVSDTSSTPTRN-PMVFGDHEFCETSQPGSSTPGSMSS----------QPHSELERQLSEGSCGGGPESAMGHEEMHDRILSNIKLEKVEANDCHGHK------PIDMEIRIGMVKVEREIMLHHPSSQSPANSSKEEGGNELLKHLLKNKRTPP---HALPHQRSEDSLRSEEEGSTESKAFFRQNSMDSTGTFSDSNHQDFPGPLILEDK-------KKQRNKRTPKSG-DRPAPRCKKRKKEEDESQAVYSSTDPMITPLKQQHLSLLPLMEPLVGVNFAHLMPYGGGQLDGENRLSGTFGSASLDGVSDYYSQLIYKQNNLSNPPTPPASLPPTPPPVARQKLLNGFATTEELARKGGLIAGHDVTKGLLAR--PLEFKAEEELLAQALAQGPKTVNVPASLPTPPHNNQEELRGQEHCEDRNTPDSFVPSSSPESVVGMEISRYPDLSLVKEEPPSPAMSPVIPMFPVFR--DKDVKLQEVKTEPSSVFFDSSFRSVQNGSNTGLVSIAIMLKPAAAENITDVVAAIADLIRVKIPSSYEVSSGPGG-SFG---AIKTSVDPQCLASALPNGPRALRQAPQHLLLQH-----------NHNKNIGGEQYRDGQ-VRPGSKQQWCQHCKVVVLGKGVRKITKDEEVKPQESR---LCSDGGLVFCSHSCLILHSSSSQSNGNADNKASVPLLSESALKQSFSKVQHQYSNNMSSLDVHCLAQLQPKPSSP-APYLHMAFAPAKAIKTESKPRSISEGHLKVTVKLKPR---LHSHLEDKQWHHGKRWKGLRWRKWTIDIAMPKVAPQS-SESELEERLKQLTTSLRPCLTIRDQRRCCFCQQIGDGMTDGPARLLNLDLDTWVHLNCALWSSEVYETQAGALINVGLARQRGQTVVCAFCQRLGATSGCHRLRCLNIYHFTCALQAGCTFFKDKTMLCHQHRPRGAGAAAG--LHVEHQLRCFSVFRRVYVQRDELRQLAAAVQQPERGHTFRVGSLLFHAMGQLPPALMPTFHSSTAIFPPGYEATRLYWSMRHGQKRCRYVCSVEEHEGRAEFSIRVIEQGYEDLVLTDTSAKGVWEKVLGPVAERRAETGMLRLFPIYLKGEDLFGLTISAVTRIAESLPGVEACSRYRFRYGRNPLLVLPLSMNSSGSARSELQTYPQHERVKILS-SWPRISRCIQN--STVAASASSHSKHFVHSKSSQYRRLASDWKSNVYLAHSRIQGLGLFAARAIEKQTMVIEYMGDILRTEVAMRRELLYKAKNRPAYMFCIDSERVIDATNSGSPARYINHSCSPNCVAEVVTFERGYKIIISAACRIERGEELCYDYKLTPVNDQSKIPCHCGAAKCRKWIN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0LYY3-1", "uniprot_id": "A0ABK0LYY3_RAT", "id": "A0ABK0LYY3-1", "name": "Histone-lysine N-methyltransferase 2C", "aln": "MSSEEDRSAEQQQPPPAPPEEPGAPAP-SPAAADKRPRGRPRKD------GASPFQRARKKPRSRGKSTVEDEDSTDGLETTETENIVETAEVKEQSVEEDAETEVESSK------QPASALQRSVSEDSAHSLVSVGVEAKISEQLCAFCYCGEKSSLGQGDLKQFRVTPGLTLP-WKDQPSNK-DVGDSGIATCEKIQNYAPRKQRGQRKERSLQQS-----IVSCVSVSTQTACEDQPGKLWDELSLVGLPDAIDVQALFDSTGTCWAHHRCVEWSLGICQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEEKCTQMYHYPCAAGAGTFQDFSHFFLLCPEHIDQAPERSKED-ANCAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLRRAGWQCPECKVCQNCRQS-GEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCRICIECGTRS-----SAQWHHNCLICDTCNQQQDN--LCPFCGKCYHPELQKDMLHCNMCKRWVHLECDKPTDQELDSQLKEEYICMYCKHLGAEIDPLHPGNEVEMPELLPTDDSSGMEIEGTEDEVVFLEQTVNEDVSGHQSPPGIVPDAVQVYTEEPQKSDPLESPDTVGLITS-ESSENKTNPDLANEISHEVDTEKTEMFYKEGLVCEEDQ-SEDRMEVTENIEVLPHQTIVPQEELLPSEGSE--VAPEEPSPSESAVELAAP--EALVSPHSE-SSLSHKGPLVIERVQEEMEQKENSEFPTGCEDFEMTLAVDGCVKGSSCQGDKSAELPAEEESPFSSGTDLNKADVSSSSTLRPD-----------------LPSCDMLHGYPSAFNSAAGSVMPTTYISVTPKIGMGKPAITKRKFSPGRPRSKQGAWSNHNTVSPPSWSPDIAEGREIFKPRQLSGSAIWSIKV-GRGSGFPGKRRPRGAGLSGRGGRGRSKLKSGLGAVVLPGVSAAD-ISSNKDEEENSMHNTVVLFSSSDKFTLHQDMCVVCGSFGQGEEGRLLACSQCGQCYHPYCVSIKITKVVLSKGWRCLECTVCEACGKATDPGRLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLRCEWQNNYTQCAPCASLSSCPVCCRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYMPVSNVPSS------DCCDSSLVAQIVTKVKELDPPKTYTQDGVCLTESGMSQLQSLTVTAPRRKRTKPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSR-EGELMDCDGKSESSPEREAGDDETKGIEGTDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKAKRSVVRKDSSGSISEQLSNRDDGWREQFPDTLVDE----PVSVADSTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQNKLSVDNLSEDAAQLSYKT----GFMDPSSDPLLCSSSASAKPGTQGT-ADDPLADISEVLNTDDDILGIISDDLAKSVDHSGLDLCTFQVGSSP---FPLDIGPIADDASSLPQPSVSQS-SRPLSEEQLDAILSPELDKMVTDGAILGKLYKIPELGGKDVEDLFTAVLSPAPTQPAPLPQPPPP-QPLPVHTQDVFS----------RMPLMNGLIGPSPHLPHHSLPAGSA---LGTFPAIAQSPYTDVRDKSLAFNVMASDANSSWVPTAPS--------MEGENDSLSNAQRSTLKWEKEEALGEVATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQ-----QQQDSIDPTSR--IDSDLFKDPLKQRESEHEQEWKFRQ------------QMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQQQQQQQQQQQQQQQQQQQLASQHLLVAPGSDPPSSGAQSPLTPQTGNGSVSPAQTFHKDLFSKHLPSTPASIPSDDVFVKPQPPPPPSTPSRIPNQESLSQSQNSQPPSPQMFSPGSSHSRPPSPVDPYAKMVGTPRPPPVGHSFPRRNSVTPVENCVPLSSVPRPIHMNETSATRPSPARDLCASSMTNSDPYAKPPDTPRPMMT-DQFPKPFSLPRSPVISEQSTKGPLAAGA-SDHFTKPSPRTDAFQRQR-----LPDPYAGPSLTPAPLGNGP--FKTPLHPPPS-QDPYGSLSQASRRLSVDPYERPALTPRPVDNFSHNQSNDPYSQPPLTPHPAMGESYTH--------SSRAFSQPGTISRSASQDPYSQPPGTPRP-----VIESYSQTSGTARSN---------QDPYSQPPGTPRPNTIDPYSQQPPTPRPSPQTDMFVTS-------VASQRHTDPYTHHLGPPRSG-------------ISVPYSQPPAAPRPRTSEGFTRSSSARPALMPNQDPFLQAAQNRVPGLPGPLIRPPDTCSQTPRPAGPGLTDTFSHASPSGVRDPYDQPPMTPRPHSESFGASQVVHDLVDRPVPGSEGNFSTSSNLPVSSQGQQFSSVSQLPGPVPTSGGTDTPNTVNMSQADTEKLRQRQKLREIILQQQQQKKIASRQEKGPQDTAVVPHPLPLPHWQPESIN---QAFTRPPPPYPGNTRSPVIPPLGPRYAVFPKDQRGPYP-----------PEVAGVGMRPHGFRVGFPGASHGPMPSQDRFHVP-QQIQGS----GIPPNIRRPMSMEMPRPSNNPPINNPVGLPQHFPPQGLPVQQHNILGQAFIELRHRAPDGRSRLPFAAS--PGSAMESPSHPRH-----GNFLPRPDFPGPRHTDP-IRQPPQCLPNQLPVHANLEQVPPSQPEQGHPAHQSSIVMRPLTHPLSGEFSEAPLSTSTPTETPPDNLEIAGQSSDGLEEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGKGDDLDTLDNLETNDPNLDDLLRSDEFDIIAYTDPELDLGDKKSMFNEELDLNVPIDDKLDNQCVSVEPKIRDQGDKTMVLEDKDLPQKKSSGISEIKTEALSPHSKEEPESDIKNCDDSRGDAEIACSQAS-GQTSHSDRGKPSLLTTDQEMLEKRNNRENAAPGVCAIQESTPLPAQDVMNSCDITGSTPVLSSLLSNEKCDSSDIRPSVSSPP-TLPISPSTHGSSLPPTLIPP-GPLLDNTMNSNVTVVPRVNHAFSQGVPVNPGFLQGQSSVNH-LGTGKPTNQTVPLTNQSSTSGMPGPQQLMMPQTLAQQSRE-RPLLLEEQPLLLQDLLDQERQEQQQQRQMQAMIRQRS-EPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNSLGMPPMVMSRFPFMGPSMAGVQTSEGQTLMPQAVAQDGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQQQQQQQQQQQQQQQQQQCALAPPILMPGVQPQPPLVPGASPLTMSQPNFPMVSQQLQHQQHTAVISGHTSPARMPGLPGWQSSSAPAHLPLNPSRIQPPTAQLSLKTCTPAPGAVSSANPQNGP--------------------PPRVEFDDNNPFSESFQERERKERLREQQERQRVQLMQEVDRQRALQQRMEMEQHGLMGAELAN-RTPVSQMPFYASDRPCDFLQPPRPLQQSPQHQQQIGPVLPQQTVQQGSVNSPPNQTFMQTNERRQVGPTPFVPDSPSASGGSPNFHSVKQGHGNLSGSSFQQSPLRPP--FTPILPGKPPVANSSVPCGQDPAVTAQGQNFSGSSQSLIQLYSDIIPEEKGKKKRTRKKKKDDDAESSKAPST---PHSDCTAPPTPGLSETTSAPAVSTPSELPQQRQQEAVEPVRVPTPNVATGQPCIESENKLPSSEFIKETSSQQTPVSSEADKPSGEASN-KSEERKLETAEIQPCPSQEDTKVEEKTGSKIK-DTAAGP-VSSIQCPSNPARTPVTKGDTGNELLKHLLKNKKASS-----LLTQKPEGTLSSDESSTQDGKLVEKQNPAEGLQTLGAQMQGGFGGGNSQLPKTDGGSETKKQRSKRTQRTG-EKAAPRSKKRKKDEEEKQAVCSSSD-SFTHLKQQ-LSLLPLMEPIIGVNFAHFLPYGSGQFNSGTRLLGTFGSAALEGVSDYYSQLIYKQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTRALGPKPFQLPFRPQDDLLARAIAQGPKTVDVPASLPTPPHNNHEELRIQDHYGDRDTPDSFVPSSSPESVVGVEVNKYPDLSLVKEEPPEPVPSPIIPILPSISGRDSESRRNDIKTEPGTLFFTSPFGSSPNGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGLEYRQHLLLRGPPPGSANPPRLATSYRLKQPNVPFPPASNGLSGCKDSSHGIAEGTSLRPQWCCHCKVVILGSGVRKSFKDLTFANKGSRESTRRTEKDIVFCSNNCYILHSTTAQAK-ISDNKEPLPSLPQSPMKE-PSKAFHQYSNNISTLDVHCLPQFQEKVSPPASPPITFP-PAFEAAKVESKP-----DELKVTVKLKPRLRTVPVGLEDCRPLN-KKWRGMKWKKWSIHIVIPKGTFKPPCEDEIDEFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCATKAQCMFFKDKTMLCPMHKPKG---------IHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHAIGQLLPQQMQAFHSSKALFPVGYEASRLYWSTRYANRRCRYLCSIEEKDGRPVFVIRIVEQGHEDLVLSDSSPKDVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPGVEACENYTFRYGRNPLMELPLAVNPTGCARAEPKMSAHVK----RPHTLNSTSTSKSFQSTVTGELNAPYSKQFVHSKSSQYRRMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSNRRIQKGEELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BRH4-1", "uniprot_id": "KMT2C_MOUSE", "id": "Q8BRH4-1", "name": "Histone-lysine N-methyltransferase 2C", "aln": "MSSEEDRSAEQQQPPPAPPEEPGAPAP-SPAAADKRPRGRPRKD------GASPFQRARKKPRSRGKSTVEDEDSMDGLETTETENIVET-EIKEQSVEEDAETEVDSSK------QPVSALQRSVSEESANSLVSVGVEAKISEQLCAFCYCGEKSSLGQGDLKQFRVTPGLTLP-WKDQPSNK-DIDDNSSGTCEKIQNYAPRKQRGQRKERPPQQS-----AVSCVSVSTQTACEDQAGKLWDELSLVGLPDAIDVQALFDSTGTCWAHHRCVEWSLGICQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEEKCTQMYHYPCAAGAGTFQDFSHFFLLCPEHIDQAPERSKED-ANCAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRAGWQCPECKVCQNCKQS-GEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCRICIECGTRS-----STQWHHNCLICDTCYQQQDN--LCPFCGKCYHPELQKDMLHCNMCKRWVHLECDKPTDQELDSQLKEDYICMYCKHLGAEIDPLHPGNEVEMPELP-TDYASGMEIEGTEDEVVFLEQTVNKDVSDHQCRPGIVPD-VQVYTEEPQKSNPLESPDTVGLITS-ESSDNKMNPDLANEIAHEVDTEKTEMLSKGRHVCEEDQ-NEDRMEVTENIEVLPHQTIVPQEDLLLSEDSE--VASKELSPPKSAPETAAP--EALLSPHSE-RSLSCKEPLLTERVQEEMEQKENSEFSTGCVDFEMTLAVDSCDKDSSCQGDKYVELPAEEESTFSSATDLNKADVSSSSTLCSD-----------------LPSCDMLHGYPPAFNSAAGSIMPTTYISVTPKIGMGKPAITKRKFSPGRPRSKQGAWSNHNTVSPPSWAPDTSEGREIFKPRQLSGSAIWSIKV-GRGSGFPGKRRPRGAGLSGRGGRGRSKLKSGIGAVVLPGVSAAD-ISSNKDEEENSMHNTVVLFSSSDKFTLQQDMCVVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKGWRCLECTVCEACGKATDPGRLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLRCEWQNNYTQCAPCASLSSCPVCCRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYMPVSNVPSS------DCCDSSLVAQIVTKVKELDPPKTYTQDGVCLTESGMSQLQSLTVTAPRRKRTKPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSR-EGELMDCDGKSESSPEREAGDDETKGIEGTDAIKKRKRKPYRPGIGGFMVRQRSRTGQGKAKRSVVRKDSSGSISEQLPSRDDGWREQLPDTLVDE----PVSVAENTDKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQNKLSVDNLSEDAAQLSFKT----GFLDPSSDPLLSSSSTSAKPGTQGT-ADDPLADISEVLNTDDDILGIISDDLAKSVDHS-------------------DIGPTTADASSLPQPGVSQS-SRPLTEEQLDGILSPELDKMVTDGAILGKLYKIPELGGKDVEDLFTAVLSPATTQPAPLPQPPPPPQLLPMHNQDVFS----------RMPLMNGLIGPSPHLPHNSLPPGSG---LGTFPAIAQSPYTDVRDKSPAFNAIASDPNSSWAPTTPS--------MEGENDTLSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQ-----QQQDSIDPSSR--IDSDLFKDPLKQRESEHEQEWKFRQ------------QMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQQQQQQQQ-----------LASQHLLVAPGSDTPSSGAQSPLTPQAGNGNVSPAQTFHKDLFSKHLPGTPASTPSDGVFVKPQPPPPPSTPSRIPVQESLSQSQNSQPPSPQMFSPGSSHSRPPSPVDPYAKMVGTPRPPPGGHSFPRRNSVTPVENCVPLSSVPRPIHMNETSATRPSPARDLCASSMTNSDPYAKPPDTPRPMMT-DQFSKPFSLPRSPVISEQSTKGPLTTGT-SDHFTKPSPRTDAFQRQR-----LPDPYAGPSLTPAPLGNGP--FKTPLHPPPS-QDPYGSVSQTSRRLSVDPYERPALTPRPVDNFSHSQSNDPYSHPPLTPHPAMTESFTH--------ASRAFPQPGTISRSASQDPYSQPPGTPRP-----LIDSYSQTSGTARSN---------PDPYSQPPGTPRPNTIDPYSQQPPTPRPSPQTDMFVSS-------VANQRHTDPYTHHLGPPRPG-------------ISVPYSQPPAVPRPRTSEGFTRPSSARPALMPNQDPFLQAAQNRVPGLPGPLIRPPDTCSQTPRPPGPGRIDTFTHASSSAVRDPYDQPPVTPRPHSESFGTSQVVHDLVDRPVPGSEGNFSTSSNLPVSSQGQQFSSVSQLPGPVPTSGGTDTQNTVNMSQADTEKLRQRQKLREIILQQQQQKKIASRQEKGPQDTAVVPHPVPLPHWQPESIN---QAFTRPPPPYPGSTRSPVIPPLGPRYAVFPKDQRGPYP-----------PEVAGMGMRPHGFRFGFPGAGHGPMPSQDRFHVP-QQIQGS----GIPPHIRRPMSMEMPRPSNNPPLNNPVGLPQHFPPQGLPVQQHNILGQAFIELRHRAPDGRSRLPFAAS--PSSVIESPSHPRH-----GNFLPRPDFPGPRHTDP-IRQPSQCLSNQLPVHPNLEQVPPSQQEQGHPAHQSSIVMRPLNHPLSGEFSEAPLSTSTPAETSPDNLEIAGQSSAGLEEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGKGDDLDTLDNLETNDPNLDDLLRSGEFDIIAYTDPELDLGDKKSMFNEELDLNVPIDDKLDNQCASVEPKTRDQGDKTMVLEDKDLPQRKSSVSSEIKTEALSPYSKEEIQSEIKNHDDSRGDADTACSQAASAQTNHSDRGKTALLTTDQDMLEKRCNQENAGPVVSAIQGSTPLPARDVMNSCDITGSTPVLSSLLSNEKCDDSDIRPSGSSPP-SLPISPSTHGSSLPPTLIVPPSPLLDNTVNSNVTVVPRINHAFSQGVPVNPGFIQGQSSVNHNLGTGKPTNQTVPLTNQSST--MSGPQQLMIPQTLAQQNRE-RPLLLEEQPLLLQDLLDQERQEQQQQRQMQAMIRQRS-EPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNSLGMPPMVMSRFPFMGPSVAGTQNNDGQTLVPQAVAQDGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQQQQ--------------CALAPPILMPGVQPQPPLVPGATSLTMSQPNFPMVPQQLQHQQHTAVISGHTSPARMPSLPGWQSNSASAHLPLNPPRIQPPIAQLSLKTCTPAPGTVSSANPQNGP--------------------PPRVEFDDNNPFSESFQERERKERLREQQERQRVQLMQEVDRQRALQQRMEMEQHCLMGAELAN-RTPVSQMPFYGSDRPCDFLQPPRPLQQSPQHQQQIGPVLQQQNVQQGSVNSPPNQTFMQTNEQRQVGPPSFVPDSPSASGGSPNFHSVKPGHGNLPGSSFQQSPLRPP--FTPILPGTSPVANSNVPCGQDPAVTQ-GQNYSGSSQSLIQLYSDIIPEEKGKKKRTRKKKKDDDAESGKAPST---PHSDCAAPLTPGLSETTSTPAVSSPSELPQQRQQEPVEPVPVPTPNVSAGQPCIESENKLPNSEFIKETSNQQTHVNAEADKPSVETPN-KTEEIKLEKAETQ--PSQEDTKVEEKTGNKIK-DIVAGP-VSSIQCPSHPVGTPTTKGDTGNELLKHLLKNKKASS-----LLTQKPEGTLSSDESSTKDGKLIEKQSPAEGLQTLGAQMQGGFGGGNSQLPKTDGASENKKQRSKRTQRTG-EKAAPRSKKRKKDEEEKQAMYSSSD-SFTHLKQ--------------------------------------------------------QNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVARALGPKPFQLPFRPQDDLLARAIAQGPKTVDVPASLPTPPHNNHEELRIQDHYGDRDTPDSFVPSSSPESVVGVEVNKYPDLSLVKEEPPEPVPSPIIPILPSISGKNSESRRNDIKTEPGTLFFTSPFGSSPNGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSNAPDVPPMGLVSSHRVNPSLEYRQHLLLRGPPPGSANPPRLATSYRLKQPNVPFPPTSNGLSGYKDSSHGPAEGASLRPQWCCHCKVVILGSGVRKSCKDLTFVNKGSRENTKRMEKDIVFCSNNCFILYSSAAQAK-NSDNKESLPSLPQSPMKE-PSKAFHQYSNNISTLDVHCLPQFQEKVSPPASPPISFP-PAFEAAKVESKP-----DELKVTVKLKPRLRTVPVGLEDCRPLN-KKWRGMKWKKWSIHIVIPKGTFKPPCEDEIDEFLKKLGTCLKPDPVPKDCRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCATKAQCMFFKDKTMLCPMHKPKG---------IHEQQLSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQLLPQQMQAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIEEKDGRPVFVIRIVEQGHEDLVLSDSSPKDVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPGVEACENYTFRYGRNPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQSTVTGELNAPYSKQFVHSKSSQYRRMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSNRRIQKGEELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEZ4-1", "uniprot_id": "KMT2C_HUMAN", "id": "Q8NEZ4-1", "name": "Histone-lysine N-methyltransferase 2C", "aln": "MSSEEDKSVEQPQPPPPPPEEPGAPAP-SPAAADKRPRGRPRKD------GASPFQRARKKPRSRGKTAVEDEDSMDGLETTETETIVET-EIKEQSAEEDAEAEVDNSK------QLIPTLQRSVSEESANSLVSVGVEAKISEQLCAFCYCGEKSSLGQGDLKQFRITPGFILP-WRNQPSNKKDIDDNSNGTYEKMQNSAPRKQRGQRKERSPQQN-----IVSCVSVSTQTASDDQAGKLWDELSLVGLPDAIDIQALFDSTGTCWAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEEKCTQMYHYPCAAGAGTFQDFSHIFLLCPEHIDQAPERSKED-ANCAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRAGWQCPECKVCQNCKQS-GEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCRICIECGTRS-----SSQWHHNCLICDNCYQQQDN--LCPFCGKCYHPELQKDMLHCNMCKRWVHLECDKPTDHELDTQLKEEYICMYCKHLGAEMDRLQPGEEVEIAELT-TDYNNEMEVEGPEDQMVFSEQAANKDVNGQESTPGIVPDAVQVHTEEQQKSHPSESLDTDSLLIA-VSSQHTVNTELEKQISNEVDSEDLKMSSEVKHICGEDQ-IEDKMEVTENIEVVTHQITVQQEQLQLLEEPETVVSREESRPPKLVMESVTLPLETLVSPHEESISLCPEEQLVIERLQGEKEQKENSELSTGLMDSEMTPTIEGCVKDVSYQGGKSIKLSSETESSFSSSADISKADVSSSPTPSSD-----------------LPSHDMLHNYPSALSSSAGNIMPTTYISVTPKIGMGKPAITKRKFSPGRPRSKQGAWSTHNTVSPPSWSPDISEGREIFKPRQLPGSAIWSIKV-GRGSGFPGKRRPRGAGLSGRGGRGRSKLKSGIGAVVLPGVSTAD-ISSNKDDEENSMHNTVVLFSSSDKFTLNQDMCVVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKGWRCLECTVCEACGKATDPGRLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLRCEWQNNYTQCAPCASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYMPASNVPSS------DCCESSLVAQIVTKVKELDPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRSKPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSR-EGELMDCDGKSESSPEREAVDDETKGVEGTDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKTKRSVIRKDSSGSISEQLPCRDDGWSEQLPDTLVDE----SVSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSKISLDNLSEDGAQLLYKTNMNTGFLDPSLDPLLSSSSAPTKSGTHGP-ADDPLADISEVLNTDDDILGIISDDLAKSVDHS-------------------DIGPVTDDPSSLPQPNVNQS-SRPLSEEQLDGILSPELDKMVTDGAILGKLYKIPELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFS----------RMPLMNGLIGSSPHLPHNSLPPGSG---LGTFSAIAQSSYPDARDKNSAFNPMASDPNNSWTSSAPT--------VEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQ-----QQQDSIDPSSR--IDSELFKDPLKQRESEHEQEWKFRQ------------QMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQ------------------FGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMT-DQFPKSLGLSRSPVVSEQTAKGPIAAGT-SDHFTKPSPRADVFQRQR-----IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAH--------PSRAFSQPGTISRPTSQDPYSQPPGTPRP-----VVDSYSQSSGTARSN---------TDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTP-------VTNQRHSDPYAHPPGTPRPG-------------ISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQDSPAVPHPGPLQHWQPENVN---QAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYP-----------PDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGS----GVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAP--PGSVVEASSNLRH-----GNFIPRPDFPGPRHTDP-MRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYTDPELDMGDKKSMFNEELDL--PIDDKLDNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNVDTPCSQAS-AHSDLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTLPASPSNHVSSLPP-FIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQNRE-RPLLLEEQPLLLQDLLDQERQEQQQQRQMQAMIRQRS-EPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNNLGMPPMVMSRFPFMGQVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQ-----------------QCAMAPPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGP--------------------PPRVEFDDNNPFSESFQERERKERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPS--FTPALPAAPPVANSSLPCGQDSTITH-GHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPST---PHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPA-KTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACP-VSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSS-----LLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGN-QLPKTDGGSETKKQRSKRTQRTG-EKAAPRSKKRKKDEEEKQAMYSSTD-TFTHLKQ--------------------------------------------------------QNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGLEYRQHLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESAALRPQWCCHCKVVILGSGVRKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCFILYSSTAQAK-NSENKESIPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKASPPASPPIAFP-PAFEAAQVEAKP-----DELKVTVKLKPRLRAVHGGFEDCRPLN-KKWRGMKWKKWSIHIVIPKGTFKPPCEDEIDEFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKTMLCPMHKPKG---------IHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQLLPQQMQAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIEEKDGRPVFVIRIVEQGHEDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPGVEACENYTFRYGRNPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQSTVTGELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1H0-1", "uniprot_id": "Q9W1H0_DROME", "id": "Q9W1H0-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------MSTNVVVSMEEKAVADDLPYFPEKFPGKVCCLCNLGEKSALGQGEILQLKAPAPAEIK-------------------------DKYPTDRLREDGSRLLYG--------------PKQAASSSGDCHYELDKIGQPDVVHPAEFLD-EGFVYVHRMCIMWSLRKSQISDADGAYFATHFAEFLEQKCNFCGRYGASINCKMN-CRQVHHWPCAAAAGCLLILESFTVFCTEHLSQVPVICSDNNVECLSCSSLGDLSKLIMCSTCGDHFHSTCIGLANLPDTRSGWNCARCTKCQICRQQDSNDTKYVKCEQCQKTYHASCLRPVISAIPKYGWKCNRCRVCTDCGSRTPGGGSSSRWHSHYTICDSCYQQRNKGFSCPICQKAYRAASHKEMVKCSWCNKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKSNSSGPGSS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQTIDSIVLSAMDSSSEQLSLKEIELDPLEGKPTMDPSSDELHKLPTGKKK-------------------------------------VCLTSVRGRSGKFVLHRMGVMSQINKKRSTRGKGRQLALPTISS------DRCLSRSMETDLTSDKKLLLCSARDKFIQAQDICVMCGSLGIESDSVMITCAQCGQCYHPYCAGVKPSRGILQKGWRCLDCTVCEGCGKKNDEARLLLCDECDISYHIYCVNPPLETVPTGNWKCSFCTLCQKCGRNPTEKSEFGDSNMLECPSCTSQSSCPVCKVSYSNGEMIIQCEHCELWAHFHCDSVNAQLTIDHYDNNVYKCFKCRCSTRSTNSLAD-------AKFGNEDSLAITPQGSKPFVHITASSGPSFDSKSGAERNHPTLSGDMPESAPEALHWIDGVCLSESGLGMIKSLSTEIKRKRKMRQALGNGKDGQLEAAAEEALEKYK-----------DGMVWDGTENAIPEGFTISINDEGVNILRKKRQRNLQKLGIGGFSVRNRGLKKDSEETTAVDQINS-------LMTMDKKKKIIRKKQKNKLIEAYPVYLQEAFFGKPLLEGGELVMADTDSSDEIDAS-----------MKVYFTRPEGKSPANQDTLAVNKSPAKTVKKVKAELKTENKTVFIQQMPMGIQNKNG--------------------TTPVSNVFDPLQAEISNTVFANRHPLDALASPNVPELDMANSVSTVPSAEVIEKPMRES------PAVLVDSFMVPNQLPQEQKFHNQLYLGG--------------------NTLVNPAQQLQFRQQAPQNAN--KQNMQTIMSQVVLQTEKRPEEEQKVVEPVTETLN--------------AG-------TQKTAEKMRKDEDLGLMATISAVLYANTEHPNLKELFPIWNDRCKQILKRWRSLCNEKKAPFLQKAKDNRSALRQRREQNK-----------------------------IPMPPKPQKQEEMGRVWKQPP---------------------------------------------------------------------------------------------------------------------------------------------------KLKEDQPNMFVTYNGNAYDMGNYVGGSAQAASNNPNPHHVMPNVNDN-------------------------------LVIKATMQRTQVHTTAASTLKMTTVDNRLELNTAVYGTEPIGDKKLRNLLQKN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STEPMLMGANSDLFLGNDVMRLGMMQNTP----------------------------------------------------------------------------ITQNNPMLSISGKSQPSEGRSLEQDVKLGEPQEATSSAVELEN-------------------VGFSDLLGGLGEGDDDDLLKSLTSEMG--------------------------DDFNILEYADPELDVN-----------VLNSLDFDDNEKCST------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * * ::*.:* * :* ****:: : .. . : . . ** :* ** :. ::: * .* * ** .: . . . . . : * :* : **:*:* : * : .*:**...** : : ::*.:*:. . .: .:* *.* *** . ::* :** *:*. *:.:: * *:**:*..*. * *:: .:*:* : *: *:* **: **:* :.::*. **:*:.** * :** *. . :* : :*: * :*::. * : . : * *:::.: * . : :: : . . : . .: .: * *. .: :*:..*: : : **.. * :* : :. : . : .: : . : : : ...::: *: *.* **:**:***:* :. :::*:********:*..:* :: :*.******:*****.**: .* .******:****** **::***:.**.*.***.:*. * :** ... :.* :* .*:* : **:* .* : ::*:**.:*: * * *:.:::: ::: : :.* *: . . :* . : :..* .: ... : : : . . *: * : * . .:* *. .: :: :*. : : ::.: *: *. : * : :.:.. : : :* . . : ... : . :: * : :*:*.** *::* ********* **: .. :. :.: .. : . . *::: . : : . ... . . . . : * **** : :: . : . .*** * : : * :: . :: . . .: .: : : . . :*::: * .*:* ** :**::.***:* :.***:: :* * * *** * **. ..:.:**::***:***:*** .: * . : * :::.* : ** : .*::* . .. : . ..: .* * ... . .: .: ::....* : : : : : * : :.. ::*: :.* . : .:. . :. . :: ..:* . :. * *..*. : ..*::: *:*.:::: : :: . ", "identical_positions": 267, "similar_positions": 447, "identity": "5.08%" }, { "cls_id": "homologset.agr.MGI:2444961", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C4S8-1", "uniprot_id": "DEN2A_MOUSE", "id": "Q8C4S8-1", "name": "DENN domain-containing protein 2A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLEARVDMLSSNMIISGPAADLGAKEASRPWKKQLNSVPNSGPSARARAQPQPLSIKDKISKWEGKKEPPASDPARQTDGQEDHLPSCKVERRGSE-----LTRTKNGMRLETERLQ---NDSRARTVCQDTEQLPGPRPIDGQPELSQHRGRELKPSDLRFQSDHLSVLRQVKRLEKALKDGSAGLDPQMPGTCYSPHCLPDKTEEDLPSLESHEKGGVLAAGRRAH--HLEVREPGPEISEDWKG---------QESVYRGSRWYPPKPFINPVPKPRRTFKHAGEGDKDVSPGISFKKEKRNLPPLPSLPPPPPPLPSSPPPTSVNRRLWTGRQRPSADHRKSYEFEDLLQSSSENSRVDWYAQTKLGLTRTLSEENVYEDILDPPMKENPYEDVELHGRCLGKKCVLTFPASPTSSIPDTSTKQSLSKSAFFRQNSERRNLKLLDTRKLSRDGAGSPLRTSPPSTPSSPDDTFFNLGDLQNGRKKKKIPRLVLRINAIYEARRGKKRVKRLSQSTESNSGKVTDENSESDSDTEEKLKAHSQRLVNVKSRLKQAPRYSSLDRDLIEYQERQLFEYFVVVSLHKKQAGAAYVPELTQQFPLKLEKSFKFMREAEDQLKAIPQFCFPDAKDWAPVQEFTSETFSFVLTGEDGSRRFGYCRRLLPGGKGKRLPEVYCIVSRLGCFSLFSKILDEVEKRRGISPALVQPLMRSVMEAPFPALGKTIIVKNFLPGSGTEVIELCRPLDSRLEHVDFESLFSSLSVRHLVSVFASLLLERRVIFIADKLSTLSKCCHAMVALIYPFSWQHTYIPVLPPAMIDIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDLINDRFLRQMEDEDSILPRKLQVALEHILEQRNDLACDQDGGPLDCVHGPESSSLSEVVSEAFVRFFVEIVGHYPLFLTSGE--ERSLQREAFRKAVSSKSLRRFLEVFMETQTFRGFIQERELRRQDAKGLFEVRAQEYLETLPSGEHSGVNKFLKGLGNKMKFLHKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LYI0-1", "uniprot_id": "A0ABK0LYI0_RAT", "id": "A0ABK0LYI0-1", "name": "", "aln": "MGREEGAHVTADGRGAAQGRGRGRARQRPEGTQRASQAGGSGDRTRARAAGTRGAPGGRGRPRGQRRGGQRAMAPQVPAAPAPGNRELRPRTRGAASRGEAALGTLPRSPGDRRGERSIVLPRIGLTLGPKKLAESGQSRALRCAGAPGRLVKAEVAKPREASRRQLLGRSVSLQKTNPAPPLGRSPSSPHTLMLEARVDMLSSNMIISGPAADLGAKEASRPLKKQLSSVQNPGPSTQARAQP--LSIKDKISKWEGKKEPPASDPARQTDGQEDYLPSCRVERRGSE-----LTRTKNGMRLETESLQ---NDSRTRTMCQDAERLPGLRQIDGQPEPSQPRGRELKPSDLRFQSDHLSVLRQVKRLEKALKDGSAGLDPQLPGTCYSPHCLPDKTEEDQPIPESHESGVSLASGRRAH--HSEVREPGPEISEEWKG---------QENVYRGSRWHPQKPFINPVPKPRRTFKHAGEGDKDGNPGISFKKEKRNLPPLPSLPPPPPPLPSSPPPTSVNRRLWTGRQRPSADHRKSYEFEDLLQSSSENSRVDWYAQTKLGLTRTLSEENVYEDILDPPMKENPYEDVESHGRCLGKKCVLTFPGSPTSSIPDTSTKQSLSKSAFFRQNSERRNFKLLDTRKLSRDGTGSPLRTSPPSTPSSPDDTFFNLGDLQNGRKKKKIPKLVLRINAIYEARRGKKRVKRLSQSTESNSGKVTDENSESDSDTEEKLKAHSQRLVNVKSRLKQAPRYSSLDRDLIEYQERQLFEYFVVVSLHKKQAGAAYVPELTQQFPLKLEKSFKFLREAEDQLKAIPQFCFPDAKDWSPVQEFTSETFSFVLTGEDGSRRFGYCRRLLPGGKGKRLPEVYCIVSRLGCFSLFSKILDEVEKRRGISPALVQPLMRSVMEAPFPALGKTITVKNFLPGSGTEVIELCRPLDSRLEHVDFESLFSSLSVRHLVSVFASLLLERRVIFIADKLSTLSKCCHAMVALIYPFSWQHTYIPVLPPAMIDIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDLINDRFLRQMEDEDSILPRKLQVALEHILEQRNDLACDQDGGPLDCVHGPESSSLSEVVSEAFVRFFVEIVGHYSLFLTSGE--ERSLQREAFRKAVSSKSLRRFLEVFMETQTFRGFIQERELRRQDAKGLFEVRAQEYLETLPSGEHSGVNKFLKGLGNKMKFLHKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULE3-1", "uniprot_id": "DEN2A_HUMAN", "id": "Q9ULE3-1", "name": "DENN domain-containing protein 2A", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDMFSLDMIISDPAA-----EASRAGKKQLRGVQNPCPSARARPRHKSLNIKDKISEWEGKKEVPTPAPSRRADGQEDYLPSSTVERRSSDGVRTQVTEAKNGMRPGTESTEKERNKGAVNVGGQDPEPGQDLSQPEREVDPSWGRGREPRLGKLRFQNDPLSVLKQVKKLEQALKDGSAGLDPQLPGTCYSPHCPPDKAEAGSTLPENLGGGSGSEVSQRVHPSDLEGREPTPELVEDRKGSCRRPWDRSLENVYRGSEGSPTKPFINPLPKPRRTFKHAGEGDKDGKPGIGFRKEKRNLPPLPSLPPPP--LPSSPPPSSVNRRLWTGRQKSSADHRKSYEFEDLLQSSSESSRVDWYAQTKLGLTRTLSEENVYEDILDPPMKENPYEDIELHGRCLGKKCVLNFPASPTSSIPDTLTKQSLSKPAFFRQNSERRNFKLLDTRKLSRDGTGSPSKISPPSTPSSPDDIFFNLGDPQNGRKKRKIPKLVLRINAIYEVRRGKKRVKRLSQSMESNSGKVTDENSESDSDTEEKLKAHSQRLVNVKSRLKQAPRYPSLARELIEYQERQLFEYFVVVSLHKKQAGAAYVPELTQQFPLKLERSFKFMREAEDQLKAIPQFCFPDAKDWVPVQQFTSETFSFVLTGEDGSRRFGYCRRLLPGGKGKRLPEVYCIVSRLGCFSLFSRILDEVEKRRGISPALVQPLMRSVMEAPFPALGKTILVKNFLPGSGTEVIELCRPLDSRLEHVDFESLFSSLSVRHLVCVFASLLLERRVIFIADKLSILSKCCHAMVALIYPFAWQHTYIPVLPPAMVDIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDLVNSRFLRQMDDEDSILPRKLQVALEHILEQRNELACEQDEGPLDGRHGPESSPLNEVVSEAFVRFFVEIVGHYSLFLTSGEREERTLQREAFRKAVSSKSLRHFLEVFMETQMFRGFIQERELRRQDAKGLFEVRAQEYLETLPSGEHSGVNKFLKGLGNKMKFLHKK", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**:* :****.*** ****. **** .* *. **::**.: *.******:****** *:. *:*::*****:***. ****.*: :*.:***** ** : *.. ... **.* . : : : * **** : ..****.* ****:***:**:************:********* ***:* . . *. * .:*.* . * *** **: *: ** *.*****. * ******:**************** .***.*:**************** *******:***********:.*******************.**************************************:* ***********.**.********* *******.***********:************:*** : *********** ****** ******:***:**********.************* ******************************************.** *:****************************************:****:********************* ***:***************************************************:*********************************** *****************************************.******************* ***************:*************:**********************************:*.******:**********************:***:** **** ******.*.******************.******* **:****************:********* *******************************************************", "identical_positions": 824, "similar_positions": 93, "identity": "67.87%" }, { "cls_id": "homologset.agr.MGI:2444966", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1Y9-1", "uniprot_id": "D4A1Y9_RAT", "id": "D4A1Y9-1", "name": "Trans-2,3-enoyl-CoA reductase-like", "aln": "MFKRHKSLE--RKRELLFQGLPQFTMKNNTRNFHSLSQLVLSAGPLKTTTAVKHSKTTHFEIEILDAHTRKQICIVDKVTQTSTIYDVKQKFHKACPKW-YPSRIGLQLEYGGPYLKDYITIQSVAASSIITLYFTDLGQQVGWTTVFLAEYSGPLLIYLLFYLR---SSYIYDVKESFRWPRHTVVHLACFCHCIHYIRLLLETLFVHKVSTGHSPMKNLIKGCAFYWGFTSWMAYYINHPRYTP---------PSFGNRQIIVSAINFLMCEAGNHFINTVLAHPSHTGSNA-CFPSPTYNPFTWMFFLVSCPNYTYEIGTWISFTIMTQT-LPVGIFTMLMTIQMSLWARKKHKIYRKKFNSYVHRKSAIIPFIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFZ1-1", "uniprot_id": "TECRL_MOUSE", "id": "Q8BFZ1-1", "name": "Trans-2,3-enoyl-CoA reductase-like", "aln": "MFKRHKSLE--RKRELLFQGLPQSTMKNNARNFHSLSQLVLSAGPLKTTTAVKHSKTTHFEIEILDAHTRKQICIVDKVTQTSTIHDVKQKFHKACPKW-YPSRIGLQLEYGGPYLRDYITVQSVAASSIITLYFTDLGQQVGWTTVFLAEYSGPLLIYLLFYLR---SSYIYDVKESTRWPRHPVVHLAFFCHCIHYIRLLLETLFVHKVSTGHSPMKNLIKGCAFYWGFTSWMAYYINHPRYTP---------PSFGNRQVIVSAINFLFCEAGNHFINTVLAHPNHTGSNA-CFPSPNYNPFTWLFFLVSCPNYTYEIGSWISFTVMTQT-LPVGIFTILMTIQMSLWARKKHKIYRKKFNSYVHRKSAIIPLIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5HYJ1-1", "uniprot_id": "TECRL_HUMAN", "id": "Q5HYJ1-1", "name": "Trans-2,3-enoyl-CoA reductase-like", "aln": "MFKRHKSLASERKRALLSQRATRFILKDDMRNFHFLSKLVLSAGPLRPTPAVKHSKTTHFEIEIFDAQTRKQICILDKVTQSSTIHDVKQKFHKACPKW-YPSRVGLQLECGGPFLKDYITIQSIAASSIVTLYATDLGQQVSWTTVFLAEYTGPLLIYLLFYLR---IPCIYDGKESARRLRHPVVHLACFCHCIHYIRYLLETLFVHKVSAGHTPLKNLIMSCAFYWGFTSWIAYYINHPLYTP---------PSFGNRQITVSAINFLICEAGNHFINVMLSHPNHTGNNA-CFPSPNYNPFTWMFFLVSCPNYTYEIGSWISFTVMTQT-LPVGIFTLLMSIQMSLWAQKKHKIYLRKFNSYIHRKSAMIPFIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VZL3-1", "uniprot_id": "Q9VZL3_DROME", "id": "Q9VZL3-1", "name": "very-long-chain enoyl-CoA reductase", "aln": "-----------------------------------------------------------MELEILNAKNSKPYGKVKVPSGATPIGDLRALIHKTLKQTPHANRQSLRLELKGKSLKDTDTLESLSLRSGDKIYVKDLGPQIGWKTVFLAEYAGPLIVYLIFYFR---PELVYG--KAASLPISLTTHIAAGCYTVHYVKRLLETIFVHRFSHATMPLRNLFKNCTYYWGFTAYVSYHVNHPQFTS---------PCMCT--VWGALGAFALCELGNFSVHIALRNLRPPGTKVRKIPVADGNPLTKLFDLVSCPNYTYEIGAWVSFSVLTSC-LAAYLFAFAGAFQMTIWALAKHRNYKKEFKDYPRQRRSIFPFVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q99190-1", "uniprot_id": "TECR_YEAST", "id": "Q99190-1", "name": "Very-long-chain enoyl-CoA reductase", "aln": "-----------------------------------------------------------MPITIKSRSKGLRDTEIDLSKKPTLDDVLKKISANNHNISKYRIRLTYKKESKQVPVISESFFQEEADDS-MEFFIKDLGPQISWRLVFFCEYLGPVLVHSLFYYLSTIPTVVDRWHSASSDYNPFLNRVAYFLILGHYGKRLFETLFVHQFSLATMPIFNLFKNCFHYWVLSGLISFGYFGYGFPFGNAKLFKYYSYLKLDDLSTLIGLFVLSELWNFYCHIKLRLWGDYQKKH-GNAKIRVPLNQGIFNLFVAPNYTFEVWSWIWFTFVFKFNLFAVLFLTVSTAQMYAWAQKKN-------KKYHTRRAFLIPFVF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * . . :. . .: :: : : * : * : . .:. : * :: .*** *:.* **:.** **:::: :** : .: ::* ** : *:**:***:.* . *: **: .* .** ::. ::: :. . : : * :.* *. : * .: . :* *. .****:*: :*: *:.: . * . :* : ** ** *: :.* :: ::*:::", "identical_positions": 55, "similar_positions": 89, "identity": "14.55%" }, { "cls_id": "homologset.agr.MGI:2444979", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TNU7-1", "uniprot_id": "LETM2_MOUSE", "id": "Q7TNU7-1", "name": "LETM1 domain-containing protein LETM2, mitochondrial", "aln": "-----------------------------------------------MAFYSYNSFLAIFWTRLPGHSVYPSCSHF-PSLAFLHLPDSHLRTAYIKNCGSRKYSYPSLTGNNKVHPLRTRLPQKLHT-TCWLQHVPGKPQLEQTGK-PKAASPQ-----------PTKEAKTETTEEKRSLRQKIVNELKYYYKGFSLLWIDTKVAARIVWRLLHGNALTRRERRRLLRTCADVFRLVPFMVFIIVPFMEFLIPVFLKLFPDMLPSTFESESKKEEKQKKTMAAKLEIAKFLQETMTEMARRNRAKLGDASS------QLSSYVKQV-QTGHKPSTKEIVRFSKLFKDQLALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMTLKSIKADDEIIAKEGVKALSVSELQSACRARGMRSLGLTEEQLCQQLTGWLDLHLKENVPPSLLLLSRTFYLIDVKPK---------------------------PIELPPNIETPKP-------NLGIPTPPPPE---SKENLTDSAPQLKGTKDEEFIQLPPVPSSLIAPAATI---------SKEAILQAKSQETSQNSKADSKGA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5PQQ5-1", "uniprot_id": "LETM2_RAT", "id": "Q5PQQ5-1", "name": "LETM1 domain-containing protein LETM2, mitochondrial", "aln": "-----------------------------------------------MAFYSYNSFLAIFWTRLPGHSVHPPCSHF-PPLAFFHLPDSHLRTAYMKNCGSRKYSYPGLTGNNKVHPLRTRLPQKLHT-TCWLQNHPGKPQPEQIPEEPKATDPQ-----------PTKDDQTEVAEGKWSLRQKIIDEVKYYYNGFSLLWIDTKVAARIVWRLLHGQVLTRRERRRLLRTCADVFRLVPFVVFIIVPFMEFLIPVFLKLFPDMLPSTFESESKKEEKQKKMMGAKLEIAKFLQETMTEMAKRNRAKLDDDSSDS---SQLSSYVKQV-QTGHKPSTKEIVRFSKLFEDQLALEHLRRPQLVALCKLLELQAFGTNNLLRFQLLMTLRSIKADDEVIAKEGVKALSVSELQAACRARGMRSLGLTEEQLRQQLTEWLDLHLKENVPPSLLLLSRTFYLIDVKPK---------------------------PIELPPSIETPKT-------NLGIPSSPPPE---SKEDITDPAPQLNGTK----------------------------------ILQAKSQETSQNSKANSKGA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2VYF4-1", "uniprot_id": "LETM2_HUMAN", "id": "Q2VYF4-1", "name": "LETM1 domain-containing protein LETM2, mitochondrial", "aln": "-----------------------------------------------MAFYSYNSVLAIARTRFPSHFVHPTCSSYSPSCAFLHLPDSHLNKTCMKNYESKKYSDPSQPGNTVLHPG-TRLIQKLHTSTCWLQEVPGKPQLEQATKHPQVTSPQ-----------ATKETGMEIKEGKQSYRQKIMDELKYYYNGFYLLWIDAKVAARMVWRLLHGQVLTRRERRRLLRTCVDFFRLVPFMVFLIVPFMEFLLPVFLKLFPEMLPSTFESESKKEEKQKKKMAVKLELAKFLQETMTEMARRNRAKMGDAST------QLSSYVKQV-QTGHKPSTKEIVRFSKLFEDQLALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMKLKSIKADDEIIAKEGVTALSVSELQAACRARGMRSLGLTEEQLRQQLTEWQDLHLKENVPPSLLLLSRTFYLIDVKPK---------------------------PIEIPLSGEAPKT-------DILVELPTFTE---SKENMVDLAPQLKGTKDEDFIQPPPVTSSPITPSTPISLPKGPITSSEEPTLQAKSQMTAQNSKASSKGA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6B8-1", "uniprot_id": "A0ACD6B6B8_DANRE", "id": "A0ACD6B6B8-1", "name": "", "aln": "-----------------------------------------------MAVFSSQVLLAVTRSRGSYLLSKRHGCATLPSTACIRYHSELLGRIAVTARCPR-PVYPN--TSSYVRPG-CISARPIHSSCSWLQEAKDTPADSEPIKSDPVPAAS-----------ATQPPPAPPALPRKSLGQKVLDELKHYYHGFRLLGIDTKIAGRMVWRLLHGQQLTRRERRRLMRTCADLFRLVPFMVFVIVPFMEFLLPVFLKLFPEMLPSTFETETKKEEKQKKGLAAKLELAKFLQETIAEMARRNKAAVGDETQ------KFSTYVQQVRHTGEQPSTKDIVKFSKLFEDELTLEHLERPQLVALCKLLELQPIGTNNLLRFQLMMQLRTIKADDEMIATEGVSVMTVAELQAACRSRGMRSLGLTTDQLRQQLQQWLDLHLKENVPPSLLLLSRAMYLTDLTPK---------------------------PPVIPPVPKLEKTNAPPVEADTSAKGNPLSS---SVEVMVDSAPVIKNRKSEELLEKPRGLDMPS---------------PEAQLIHAKEAELSQKSKMSANGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P91927-1", "uniprot_id": "LETM1_DROME", "id": "P91927-1", "name": "Mitochondrial proton/calcium exchanger protein", "aln": "MNALLRHKGRNLRTSHLAQNVYKRFLKSNCCACSSVNVTDEPAKEDELPRRSASTSVLELSRSLGTYRRFQPHANYGYDYSGYGFRHLHTSRTLLETSSSKIDATVKKLKNQQKEKVEEIMKEVANGQAAAVRASSAATATASSEKGQNASATAGSTSATASTTSLAKTADKSVAKPKKPLRTRIWDELVHYYHGFRLLFIDVAICSKLLWRVLNGKTLTRRENKQLQRTTSDLFRLIPFSVFIIVPFMELLLPLFIKFFPGMLPSTFQTSTDRQEKLRQSLSVRLEVAKFLQQTLDQMPVQHKEHSSEEAK------QFEAFFTKIRNPTEPVSNDEIIKFAKRFDDEITLDSLSREQLAALCRVLELNTIGTTTLLRFQLRLKLRSLATDDRVIAREGVDSLDLLELQQACKARGMRAYGLTEERLRFQLKEWIDLSLNEQVPPTLLLLSRTMLISDDSIT---------------------------TDKLKETIRVLPDAVGAHTRHAIGESEGKVDNKTKIEIIKEEERKIREEREEEREETIAKRSAIKEEIPAPYVFAEKLSGSQDLLDHKEQSSVSETDKGISSTDVQLLSEALKTLSSDKQLVVEKETIKELKEELADYKEDVEELREVRQVVKEPVRESRAAKLLYNRVNKMISQLDNVLNDLEARQHQIKQAESSDYAASSPTVEPQQMVHIDELVATIRRMKEASDEERFKVVGDLLVKLDADKDGVISVNEITKAVQSIDREATNIDKKQLEEFTELLSKLASRRRHEEIVHIDDLMNNIKVLKETSDEARLKHIEAVLEKFDADKDGVVTVNDIRKVLESIGRDNIKLSDKAIEELISLLDKEQVLQAEQKIEKAIAKSMKEAEKLKSEVDKADKDLSKLVNDIHDSAKEIQDIANEMRDKEETVPDKAKELKAEPAFKDTAKTLKDNAKDLDDLAKDPKSDPKSPTKASTGSGPAGLSGGGPSSGSSGIATGSTTESALREAAERQMEKILPSTDIGLPPTIQTPSQPPTSKKATATASTLSTTITAKKLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08179-1", "uniprot_id": "MDM38_YEAST", "id": "Q08179-1", "name": "Mitochondrial distribution and morphology protein 38", "aln": "--------------------------------------------------------MLNFASRASCVTRRQASLYFVKNQGPRLIASTIPSCHWPLRAQG------------------------------VQPNYPLSLRFYSTDKSKSVTKPV------------APTSTDAPAKPKETLMVKVKHALKHYANGTKLLGYEIKVSTKLLIKFAQGYELSRRERNQLRRTMGDVFRLIPFSAFLIIPFAELFLPFALKLFPNLLPSTYESGKDKQAKRNKLIEIRKKTSEFLHETLEESNLITYNTIENAEKKQKFLNFFRKLYSAKEGKIMTFQHDEISAIAQMFKNDSVLDNLSRPQLAAMSKFMSLRPFGNDNMLRYQIRSKLKDIMNDDKTIDYEGVESLSQEELYQACVSRGMKAYGVSKEDLVDNLKVWLELRLRQKIPSVLMVLSSTFTFGGLPKENYSKAFSPLAEKKETKSKYDDLLDLYYDGILQVLSSIPDPVYNVAKLDVS-ESKSSAAETEAEKQVAEKKIKTEEKPEETAIPKEEATAKESVIATTASAVTPKLVVVNEKAETAKTEEISQEKENAEPTDSAEATEAEEKKTSDDNEFKLNVLKEQEELIKKEEEEAKQRASREHVPDDINLDEEEEAKSVPPIPADQAAKTFVIKKD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06493-1", "uniprot_id": "YLH47_YEAST", "id": "Q06493-1", "name": "LETM1 domain-containing protein YLH47, mitochondrial", "aln": "--------------------------------------------------------MLKYRSLPIKRAIHHPAPGITPISPRIMVSRLRVIPSFNLKFNR------------------------------WNSSVPESS--KKELKTTDGNQES------------ASKVSPVKEKEKVPFKVKMQKALRHYWDGSKLLGLEIKISSKLLMKSAAGYPLTRRENLQLKRTTQDIVRLVPFAAFLIIPFAELLLPFALKLFPNLLPSTYESSKKRENKLENLRNTRKLMSEIIKNNK---SHFKPNNISEEQK-----ALFNRFYTHVRATGVPESRQQLIEVARLFTDDTVLDNVTRPYLIALAKYMNLQPFGTDVMLRYRIRYKMLELKKDDLSIYYEDAEQLSLSELKTACASRGIRSVDVEPSVLYSNLRLWLNMRLKDKIPSTLLIMATAYNYGNVQSK-----------------------ESLYDALCDVLIGIPDELYHEVKVNVVKEDEASAKQKLKQLREQEEIMKEEEQQEENAIVS----------------------VKDELSLDDQDKNIDAAAPDVKPHDTKPIGEAAAIKEK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : . :: . : :* .* ** : :. ::: : * *:***. :* ** *..**:** .*:*:** *:::*. :*:** :****::: ..:: * .: : ::::::. : : . .:: .:: * :: .*: : * * *:.: :.*..:*. :**::: : : ** * *.. : ** ** :**::: .: . * :* * :: *.:::*. *:::: : . . : . : ", "identical_positions": 56, "similar_positions": 109, "identity": "5.35%" }, { "cls_id": "homologset.agr.MGI:2444981", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A779-1", "uniprot_id": "D4A779_RAT", "id": "D4A779-1", "name": "", "aln": "-------------------------------------------MAEASHTLKQLELQNGSLEEEFVVHSLENEPQNMMESLSPRKYSSSLKFKANGDYSGSYLTLSQPVSTKRSP-----SPLGSSVRSSPSLAK-----IQGGKQF-CDGIDKNISMKPPIS-FLSSTASLSG---YPIGKADLDHYTGRDSERSFRLSEKPPYSRYSSRNKSHDSVYFLGGAEGRK---------------------ASGSLLTMWNGNSLSGTGSAPISR---SGAASMPSSPKQA----RKMNLQDNLPLQPRLSRHKEQASENVSVRTRKYSGS---SLSNMGAYSRS--LPRLYKATDNQMSPLSLPPRNSLGNSRRGQLGEKDLPHSLVDNDNYLNFSSLSSGASPYKTCLSDGNPYVSSALSVPASPRVARKMLLASTS----------------------------SDDFDRASYSGTSPSHSFLSGEPDRVLVARRN-----FSCGSMELDDSD-LESLRQSSETPQPILRERKSSISSISGRDDLMDYHRRQREERLREQEMERLERQRLETILSLCAEYTK---PEGRRLSAGTTVADVQKINKELEKLQLSDEESVFEEALVCPDARYRCHRKGSLQDVDIAGFGSLGHS-ASFLAPRGSKNDELLGDLTRMPPPSSAAFLKATNESSYLSILPKTPEDMGEEQRTQELAAMEDARMVILNNLEELEQKIKDINDQMDESSRELDMECALLDGEQKSETAELMKEKEILDHLNRKITELEKNIVGEKTKEKVKLDAEREKLERLQELYSEQKTQLDNCPEAMREQLQQQLKR---------DADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQQ-----LLREVAEYQRNIVARKEKISALKKQASHIVQQAQREQDHFVKEKNNLIMMLQREKENLCNLEKKYSSLTGGKGFPINPNTLKEGYISVNEINESCGN------------------------------------------------------------------------SMNLSPSTQFPADADAAVTEPASAVPVSQPQSSEHQSAVCSGFMPPSTLSPSVTESSSAAWPEVMATPVDSFPLNDTPPPLPAKKHRRQQPQEQQHFRSLEERKKQHKEG-LYLSDTLPRKKTTPSLSPHFSSATMGRSTTPKAHLPLGQSNSCGSVLPHSLATMTKD--AESRRILRGYN-----HQQMSEGQRQKP-EFYSRTASESNVYLNSFHYSDRSYKDQAYDTLSLDSSDSMETSISACSPDN--ISSASTSNIARIEEMERLLKQAHAEKTRLLESREREMEAKKRALEEEKRRREILEKRLQEETSQRQKLIEKEVKIREKQRAQ---ARPLTRYLPVRKEDFDLRSHVETAGHNIDTCFHVSITEKTCRGYLIKMGGKIKTWKKRWFVFDRNKRTFSYYADKHEAKLKGVIYFQAIEEVYYDHLKNANKSPNPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVIVTGAEGYTHFLL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1N2-1", "uniprot_id": "PHLB2_MOUSE", "id": "Q8K1N2-1", "name": "Pleckstrin homology-like domain family B member 2", "aln": "-------------------------------------------MAEDSHMQKQLEFQNGSLEEGFVVRSLENEPQNMMESLSPRKYSSSLKFKANGDYSGSYLTLSQPVSAKRSP-----SPMGTSVRSSPSLAK-----IQGSKQF-CDGIDKNISMKPPIS-FLSSAASLGG---YPLGKADLDHYTGRDSERSTRLSEKPPYSRYSSRNKSHDSVYFLGGLEGRK---------------------TSGSLLTMWNGNSLSCTGSSPISR---SGAASMPSSPKQV----RKMNLQDHSTLQPRLSRHKEPASENVSVRTRKYSGS---SLSNMGAYSRS--LPRLYKATDNQMSPLSLPPRSSLGNSRRGQLGEKDLPHSLVDSDNYLNFSSLSSGASPYKTCLSEGNPYVSSALSVPASPRVARKMLLASTS----------------------------SDDFDRASYSGTSPSHSFISGEPDRVLVARRN-----FSCGSMELDDSD-LESLRQSSETPQPVLRERKSSISSISGRDDLMDYHRRQREERLREQEMERLERQRLETILSLCAEYTK---PEGRRLSAGTTVADVQKINKELEKLQLSDEESVFEDALVCPDARYRCHRKGSLQDVDVAGFGNLGHS-ASFLAPRGSRSDELLGDLTRTPPSSSAAFLKATNESSYLSILPKTPEDIGEEQRTQELAAMEDARMVILNNLEELEQKIKDINDQMDESSRELDMECALLDGEQKSETAELMKEKEILDHLNRKITELEKNIVGEKTKEKVKLDAEREKLERLQELYSEQKTQLDNCPESMREQLQQQLKR---------DADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQQ-----LLREVAEYQRNIVARKEKISALKKQASHIVQQAQREQDHFVKEKNNLIMMLQREKENLCNLEKKYSSLTGGKGFPINPNTLKEGYISVNEINESCGN------------------------------------------------------------------------STNLSPSTQFPADADAAVTEPALAVPVSQPQSSE-------------------------------------------------------------HFRSLEERKKQHKEG-LYLSDTLPRKKTTPSLSPHFSSATMGRSTTPKAHLPLGQSNSCGSVLPHSLATMTKD--SESRRMLRGYN-----HQQMSEGQRQKP-EFYSRTASESNVYLNSFHYPDRSYKDQAYDTLSLDSSDSMETSISACSPDN--ISSASTSNIARIEEMERLLKQAHAEKTRLLESREREMEAKKRALEEEKRRREILEKRLQEETSQRQKLIEKEVKIREKQRAQ---ARPLTRYLPVRKEDFDLRSHVETAGHNIDTCFHVSITEKTCRGYLIKMGGKIKTWKKRWFVFDRNKRTFSYYADKHEAKLKGVIYFQAIEEVYYDHLKNANKSPNPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVIVTGAEGYTHFLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SQ0-1", "uniprot_id": "PHLB2_HUMAN", "id": "Q86SQ0-1", "name": "Pleckstrin homology-like domain family B member 2", "aln": "-------------------------------------------MEEHSYIQKELDLQNGSLEEDSVVHSVENDSQNMMESLSPKKYSSSLRFKANGDYSGSYLTLSQPVPAKRSP-----SPLGTSVRSSPSLAK-----IQGSKQFSYDGTDKNIPMKPPTP-LLNTTSSLSG---YPLGRADFDHYTGRDSERALRLSEKPPYSKYSSRHKSHDNVYSLGGLEGRK---------------------ASGSLLAMWNGSSLSDAGPPPISR---SGAASMPSSPKQA----RKMSIQDSLALQPKLTRHKELASENINLRTRKYSSS---SLSHMGAYSRS--LPRLYRATENQLTPLSLPPRNSLGNSKRTKLGEKDLPHSVIDNDNYLNFSSLSSGALPYKTSASEGNPYVSSTLSVPASPRVARKMLLASTSS-------------------------CASDDFDQASYVGTNPSHSLLAGESDRVFATRRN-----FSCGSVEFDEAD-LESLRQASGTPQPALRERKSSISSISGRDDLMDYHRRQREERLREQEMERLERQRLETILSLCAEYTK---PDSR-LSTGTTVEDVQKINKELEKLQLSDEESVFEEALMSPDTRYRCHRKDSLPDADLASCGSLSQSSASFFTPRSTRNDELLSDLTRTPPPPSSTFPKASSESSYLSILPKTPEGISEEQRSQELAAMEETRIVILNNLEELKQKIKDINDQMDESFRELDMECALLDGEQKSETTELMKEKEILDHLNRKIAELEKNIVGEKTKEKVKLDAEREKLERLQELYSEQKTQLDNCPESMREQLQQQLKR---------DADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQQ-----LLREVAEYQRNIVSRKEKISALKKQANHIVQQAQREQDHFVKEKNNLIMMLQREKENLCNLEKKYSSLSGGKGFPVNPNTLKEGYISVNEINEPCGN------------------------------------------------------------------------STNLSPSTQFPADADAVATEPATAVLASQPQSKE-------------------------------------------------------------HFRSLEERKKQHKEG-LYLSDTLPRKKTTSSISPHFSSATMGRSITPKAHLPLGQSNSCGSVLPPSLAAMAKD--SESRRMLRGYN-----HQQMSEGHRQKS-EFYNRTASESNVYLNSFHYPDHSYKDQAFDTLSLDSSDSMETSISACSPDN--ISSASTSNIARIEEMERLLKQAHAEKTRLLESREREMEAKKRALEEEKRRREILEKRLQEETSQRQKLIEKEVKIRERQRAQ---ARPLTRYLPVRKEDFDLRSHVETAGHNIDTCYHVSITEKTCRGFLIKMGGKIKTWKKRWFVFDRNKRTFSYYADKHETKLKGVIYFQAIEEVYYDHLKNANKSPNPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVIVTGAEGYTHFLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXY1-1", "uniprot_id": "A0A8M9PXY1_DANRE", "id": "A0A8M9PXY1-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "MTDIVSAMDTEANCPASILEPESDQSFNSPKSPPLDLIDTGKGLKVQTATPHLVSLGSGRLSVAITLLPLKEGVTRIGRDDAPVPQDITIEGPGIEAEH-CRIENSGGVVTLDPCGHL-CSLDGVPVSRPTQLTQGYTLCLGKSYIFRFNHPEEANRMKSMLP-QKSPVSPLVYSTDYLKFSSDFSHCLGGSGSRGMRSVSELRDLMDTLQKKKQALENSLRANGDSSPSYFSMTQSPPTTPNLLSPMTSSSPNSYQEQARRLYSSERPPFSTKVLPSTTSMPSSPRRSDPRERDTSLPYSRPMTRNQSQDSLLLN-SSDSRRTATSGS---ALSMWNGSSTG-ATDPLPPAPGGGSGAASMPSSPRLARRFHTPESGRNGGLEPVPRQRKYSAGSLTGMSSHSRSLPRLYRPADSQLTLLPIYRSPDGHISHISGISDPNHQNGHSEVISISLSNTPGTKQPVAPPDVTMTSGEATSPRQAKKVSLTSTSSYSEVDRQAMCGPSPALEIGLGERRQSFGKAGLGPPTGFRERKGSISSLSGKEELQDYHQRQRDERLREQEVERLERQRLETILNLCSGLG-----RAEQDNTGLAVADLQKINKELEKLQVSDDDSTFSDS-ASLSASISAENDYGIKFREPQAREERQVRQRKNSGHRDAR--SETTAVRGSAPTPSPRLTRIN---------KTTEDDT---QLKNDVRRIEEERIQVLNNMEELELKIKDLDNQMEESIRELEVERALLEGEQDSEMAQLQQEKDTLEQLKEKMAEIENKAQTDKSQDKAKLDAERVKLERLANLLAELKTQLDTCPEALKEQLQLQLCR---------DAETLEVETKRFEDLEFQQLERESRQDEEKESQTQH-----ILREIAEYQRSTVTRKEKLLALKKQCTQISQQAQRDKDSFVKEKNNLQMMLQREKENLVSLEKKYSELTGSLGFPVNPISMKEDCFQLADVCPPHSEFSHAHKTLSPLPADLLMFSSLLSSLTTKNAEGYVTVTELNELYSQLGVDSSPNPLPTQAQSSPDTPAMGTEPSPDPSPAESTAPPGEAELSPSSSPLSSSILSSSSFTACSHPNPKPPSVHWP------------------EDMVTFLNPSPPPPPLPAKKMRRHRQHFRSLEERKRYGKEGGAHLSDTLPRKKTQPTITPQFTCATLGRNISPKSHPPLAQSSSCGSVLNRALAISPKETHMDTHRLHKGKSKKGRSQQHVGDEHRTRLSDLSGRASSQTNVYLDSIGYQD---NGRAFDTLSVDSSDSMDTSISACSPDN--ISSASTSNVLKIEEMERLLREAQAEKHRLLEYREREMESKSRALEEERRRREDLEKRLQEETTRRQKLIEREVKLREKQRAQ---SRPLTRYLPVRKDDFDLRAHIDSAGHNTETCYHISITEKTCRGFLIKMGGKIKTWKKRWFVFDRNRRTLSYYADKHEAKLKGVIYFQAIEEVYYDHLKSAHKSPNPSLTFSVKTHDRVYYMVAPSPEAMRIWMDVIVTGAEGYTQFMI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AC58GN56-1", "uniprot_id": "A0AC58GN56_DANRE", "id": "A0AC58GN56-1", "name": "", "aln": "---------------MSISGEETLLDFS------------GRGLKVGSTTPFLISLNSG----CLTLIPLTKELSVIGCEHAESPQCVTADDPEIQPHHGVFISNTAGVITLHPNGNI-CSLDGASVTGPTKLTHGCTVCLGES-FFHFNHPEELNRMRNMLP-EKTAGPALSLNTDTTKFHSNGGSLVG-SSLRGTRSKAELQELMESLQRRKSALEASLKATADRG----YLTLSPPPSP--------QSASSYLQDRPPLSIRVPSPYSP---SSSLSMPPSPHQS---ERPISPVPNQTRARHQSQDSLLLCHSSEGRHPNSSNP---LLTMWNGSSSSYGNDALLSSRRGPSGAASMPSSPRLGRRLLARDG--ESPIEPSLRQRKYSTGSLNGLGGHSRSLPRLYR-GDAPMLSLPPRRTTKPRRSFPS---------------------------MEKPPDVTVIANVNSSSRRASLCSVGS---------------APCLDLGVGERRLSFGKGGLGP--GMGPRRGSISSLSGKEELRDYHQRQRDERLREQEVERLERQRLETILCLCSELGRTEVSRMESEPNTSAVSDLQKINRELEKLQVSDDESVFSES-ASVSVDG------GVFLGKSRG-EILNQRQRRVSGHRESRPQSPSSSMRSTAPSPSPHLR------------CKVSEDM---QLRQEVTRIEEERIQVLNNIEELEQKIRDLDTQMDESIREMEVERALLDGEQEAEVTQLQSDKEMLEQLNEKMGNMEKNSQRNQTQDKALLEAERDKVERLAELISEQKTQLDSCPEALKEQLQNQLSRLWKNRLFLLDTEALEAEKKRFEDMEFQQLEKESCQDEETESQMQQ-----LLREIAEYQRSVVSRKERLLTLKKQSTQITQQAQREKENFLKEKSNLIYMLQRERENLSSLERKYAELTGGQAFPLNPVSMKEHFRTLEERRRSN------------------------------------------------GIKE-----------------------------------GGVLLSDNGTPRKRERQSSGTLNSA-------------------------------------LNRSLSP---------KVRQQIRHIG-----------------------------------------KPHMPLSQSSSCGSVLPRTLSVNSRD--LDTRRLLKAAG-----QLYLNDE-RQRMSEMSNRAVSETNVFLEPFHYLD---NGHNFDTMSVDSTESLETSISACSPDN--ISSASTANMAKIEEMERMLREAQAEKHRLLEHRERDMELRRQALEDERRRREELERRLQEETSRRQKLVERE-------------SRPLTRYLPVRKDEFDLRGHIEAAGHHPETCFHLAITEKTCRGFLVKMGGKIKTWKKRWFVFDRNRRTLAYYADKHETKMKGVIYFQAIEEVYYDHLKNAHKSPNPSLTFSVKTHDRVYYMVAPSPEAMRIWMDVIVTGAEGYTHFLL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX80-1", "uniprot_id": "Q9VX80_DROME", "id": "Q9VX80-1", "name": "PH domain-containing protein", "aln": "---------------MSLTKKDP-------------------SLRVAASDPHLVSLGGGRLSTAVTIHYIHIGDTTIG---SAASCSISLNGSGVRPLHCTIYRSDANEVTLVPEKDSRLLIDGAPILEETKLSQGAMITIGNSNYLRFNNPDEAQMMRSAMGSNERISMPQIDFTQSARQAHELSQSLELESFYESIINPINNPSTYELECPKVFSSDLVTVNMPAK---------------------DVLGQKYASFARNLAENHRNEKQLN--NQYAKGVGSNGGYWNVPSNAAIYKEQHQQQHQQAPQDLLTKVNNDRYDRYPKAGGLQIYSMNGVNSDINNGPATGNNSGTGGGAELEDMLKICTEYADRNNSMPSTHNVSSTSSITSSPIVQNRIKTNGSLPRDKNKSPFPQQAGVASSANISLLSSSSGY-----------------------------ENVRLLGPNRVEINGQIHVPASA---------------------GDGGSSSGVSSNALAPTAAVRASHENLNQNHSATTGGKYVPQSPRTKIRTNCMSPKKDVSFGNAFALAISPPP--------------LASSAVVSTSKPIPIPSMVKPPLAPKPPAPNQQRDYEQLFKSFERKQQQLDRMVPAKRSNKNINNLTLNLQSVESQTQSPKPS-----------------------------RKPAPAPRSIHLEQRQRRELIQRRKQLKRELAELPPSAGIEGLELKLGEQP-LAPSASPRLQLQALQNRVCRLEAQRNATRVMEENQQAKLKQSIEIKQDQLKKLRAMLKQKPNNACLKEELQLVC-----------ESLESDRKTFEDLEFQYFEEESEHHASHEEFKRQEQRLMLEAELAALRIQIGPDEEEPGSPTSPGSTGSNLVNGVMSQSLFGSAELLCPKRRNQEDLMSKSVNENMFYNHKIEANTSTPKRLPLQLFEDLAGGSCEQISFN-------------------------------------------------------------------LSLQGDRFEVNPLERRVPSQDDIDRSCKVANDAPISASQG------------------------------------------------ASTKIFDSIMEIERNRKLLLAQQGHQVIEHERQKMYDLKKKSHDEARTQYLLSTQQSMEQQRQLESDANGGKDAKLFEKT---ELQKLNQKPG------EPVDDQVQKIAGDKENNVQNRKSTGSSPTTTTTTTTGGGTTPQQQRHSQPELEHHAIALGIGGGGSGGAGGANQMVARSPRPLSEANNCDATIEAPKFANGMDSSASPAVADNKRASSNSQDTASAGSGSGNSGSGGSTASDRKRVLPKHQRPLTRYLPIFSPDLNLRHHIETAGHQIDPCPHVFVDAHSCRGYLHKLGATFHAWSRRWFVLDRQRSALIYYSDKSERKPRGGAYFATIDEVYLDHLN-ASKSGRPHCTFIVKTKKRSYNLQAASDSAARIWIDAIITGAQGNLDY--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :.: .* .: : : : : : . * .: ..*:: : . : : :: *: . : . .. . . : * . . * . . . * . . : .. . . . .: : . . . . : . : . * :. . . . . .. . . * . : .:.. . .* :. ::* : :. : : . : *. : . :. . * .. : . . . . .* .* .. .: .** : :::. :: * . :* *. :.. : . : *: *:.:: .:* : : :: : .:* : : :: *. *: : : ** : *: : * ***:*** :*.** . . *. :: : *:* : . . :*. : .. . : .: . : . :* :*::*:* . . : : . . .. . : . : : . .. : : : :. ...: : : ::: : . :.: : : ... ..... .. . . .* .:: * . .. ..*. :* .. . : . :.: . *: . :.:* . .: . : : . ********: . :::** *:::***: :.* *: : ::***:* *:*..:::*.:****:**:: :: **:** * * :* ** :*:*** ***: * ** .* ** ***:.* * : *.* .* ***:*.*:***:* .: ", "identical_positions": 121, "similar_positions": 306, "identity": "7.86%" }, { "cls_id": "homologset.agr.MGI:2444989", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZP7-1", "uniprot_id": "A0A0G2JZP7_RAT", "id": "A0A0G2JZP7-1", "name": "", "aln": "MTGAGPLSVHVRVTRSKTPRRSVTHSGASTGRNVRAKMAAKPGPGSAASPG---CAGAMERVLPMLLVRIPAEETAQLGPRAQLHRELEALGSLTAAGSLQVLSLAPGSRGGSSCRLQGPFRQFLWEESQNS-TSADKPRVLVAREDCGLLIYEFDLRDGRCDAALLHSCCGRTLQKLTEDQGVSISFKSLRILSFDNSTSLLLINECLVVRVVFPGRESGIGVLGCLSLPLPAQAVDTIIDVQLCKR-FLFLLSTLGWIHIFDTVKGMHVARVDLALPREDS---EQQEPASISSFMSLKVSRDLDVLLLVSSSSTAVALNLHLYFRLHPGHLLCEGTLQDLPIEGPTGIDEDDLVNSAHNMKLTKVSFQVDRSWRAQLASLNESVRSSEPELSCYPPWFQGALCLESLESGNHSPIVPNHVFIPGDVPSGQYAFPQKEHSKTSEP-RPWRTMHLSEQEQPTELTCLSVTGFTALFIQAVGTTSCTVVLWDLETQSMQCFSLSQKCTPVDISGDQQLCLALTENGLSLILFGLTQEEFLNRLMIHGSASTVDSLCHLNGWGRCSIPIHALEAGIENRQLDTVDFFLKSKENLLTPSSKSPAPDQQQHFSSQLYLRQVEEMTPALDLLCSAIRESDSETQS--KHFAEQLLHLTLSFLNKQMRELFDHTEELDEHLQKGAAILTSYINELRTFMIKFPWKPGDAIDESDENEEVLTVKEGQVWEELRSEEVIADAILNNRIPEAQTFFRITGHSAQRLEELVRIGLDLAFDSLKKNSVEEASRLLRNMGFSVEDELLKISFYTTDKNIRDFLVEILKEKECFSEKERRTVDFVHQAERLYSGHFQENAPMQAFPRYWIKEQDCFKHKSVLDTFLKCDTKDEFTKQDHRIALNWAHWWDRQTQECILLPRISSEEYKAHSPEALWRHLTARHDWSSISLWMEEFQAQET-VSPQQSKWPPLSAAVIEQNTCCSRHMRNAILDQLARCGIFLASELEDFELLLLRLSRIGGVMQDALPVQSYRSSAGCNFDSQVILYCLEHGLQHLLYVYLDYYKLSPGNCPFLEKKELHEAHPWLEFLVQCRQVSSNLTDPKLIFQASLANAQISIPTNQASVSSMLLEGHTLLALATTMYAPGGVSQVIQHEDSENCLKKVDPQLLKMALTPYPKLKAALFPQCTAPSILPSDITLYHLIQSLPPFDPSRLFGWQSANTLAIGDAAGQLPHFSSPDLVSKYAVVEQLSYTYYLHHGRPSFAFGTFLVQELIKSKTPKQLIQQVGKEAYTLGLSSFHNPSVGAACVCFLELLGLSSLKLRVDLKMANVVLGSRRRNEDAHPSFIRESLAEKLSKLADGDRATTEELLVLLEEGVWDSIEQQGFNRLSSESSSQWSLVLQFCMLHDMK-LSVSYLRECAKANDWLQFLVHSQLHNYHPEEVETLLQYFSPVLQSHLKLASEKLSSGSISKDDS------CLQELQKNK-ETSDFFEILHRCSDESASWCWLLAEAVRHRVPILSVLASCIQGASAVPCLCVWIVTSVEDKVAAEAIEHIQISVEDHHWSLEDLSIIWRTVLTRRKIHTLIRGFRLFIKDSPLLLIMEMYELCVFFKNYGKAKVKLVEFQKSLEMLDTVATRVLPVIPATWMREQVCFLLKLMPQQCETQYELQKVLQLFVGMEQLFSDGPDVQKLYRLSQVLKDTPITISPAVISSYSTESLQRECRSILEKLKADGQFAVARRVAELASLPVDGLVIEQLTQEMQMLTHTQQWSLKQARLDFWRKCHENFKKNSVSNRAASSFFSSQAPEASEHPAEQGSLEERHLLLTLAGHWLAQEEPVPVEELEELEKQIWLCRIAQHTCGGAEEETKPSLSQHKLAPAELSSDSSASEFSFSKLAALNTSKYLDLNGLPSKEMCENTLEHREQESLNTLIGQLLDGGCVHEASRVCRYFRVYSQDLVLLLHCRALASAEASMEDLHSEIRALLSNATLPEDLESPGVPLRKVHSTSSLDSLSFAMVPPTDEVARSLQTLISRCLHGKDYCRQVLCLYELAKELGCSYGDVATRDSEAMLRAILASQRPDRCRQAQVFINTQGLEPDTVAELVAEEVTRELLTPSEGAGEKQPFNLAEESQTFLQLTALCQDRTLVGMKLLDKIPSVPHG--ELSCTTELLILAHHCFTCACYMEGIIRVLQAARMLTDNHLAPNEEYGLVVRLLTGIGRYNEMTYIFDLLHQKHYFEVLMRKK-LDPTGTLKTALLDYIKRCHPGDS-EKHNMIALCFSMCREIGENHEAAACIQLKLIESQPWEES-LKDGAQLKQLLLKALTLMLDAAESYAKDSCVRQALHCNRLTKLITLQIHFLNSGQNTMLINLGHQKLMDCIMTLPR------------FYQASIVAEAYDFVPDWAEVLYQQVILKGDFSYLEEFKQQKLLKPNIFEDISKKYKQHQPTDRVTEN----LKKLLSYCEDIYLYYKLAYEHKFFEIVNMLLKDPQTGCCLKDMLAG---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHA3-1", "uniprot_id": "SPTCS_MOUSE", "id": "Q3UHA3-1", "name": "Spatacsin", "aln": "-------------------------------------MAAQPGPGSAASPG---CAGAMERVLPMLLVRIPAEETAQLGPRAQLHRELEALGSLTAAGSLQVLSLAPGSRGGSSCCLPGPFRQFLWEESQNS-TSRDRPKLLVAREDYELLVYEFDLRDGRCDAALLHGCCGRTLQKLTEDQGVSISFKSLRILSFHNNTSLLLINRCLILRVVFPGKEPGVPVLDCLSLPLPAQAADMIIDAQLCER-FLFVLSTVGLIYIFNTMDGTQVAQVDLALLREDS---EQLEPASVSSFTSLRVSQDLDVLVLVSSASTAVALNLHLYFRQHPGHLLCEGTLEDLPIEGPPGIDEDDLVNSAHNMKLSKVSFQVDRSWRAQLLSLNESVRGSEPEVSCCAPWFQSALRLESLESADHTPTVPTHVFIPGDVPRGRCAFPQKEHVKSSDPGRPWKTMHLSEHEQPTELTCLSVTGFTALFTWAVGATSCTIGLWDLETQSMQCFSLSQKCTPVDIGGDQQLCLALTDDGLSLILFGLTQEEFLNRLMIHGSASTVDSLCHLNGWGRCSIPIHALEAGIENRQLDTVDFFLKSKENLLTPSSQSPAPDQQHPFSSHLYLRQVEEMSPALDLLCSAIRESDSETQS--KHFAEQLLHLTLSFLNKQIRELCVHTEELDEHFQKGVAILTSYINELRTFMIKFPWKPGDAIDESDVNEGVVTVKEDRVWEELSFEEVIADAILNNRIPEAQTFFRISGHSAQRLEELVRIGLDLAFDSLKKNNVEEASRLLRNMGFSVEDELLKICFYTTDKNIRDFLVEILKEKECFSEKERRTVDFVHQLEALYSGHFQENAQTQAFPRYWIKEQDCFKHKSVLDTFLKYDKKDEFHKQDHRIALNWAHRWDLQTQECILLRRLSPEEYKARSPEALWRHLTARHDCSSISLWMEEFQTQET-ESPQQSKWPPLSADIIEQGTCCHSHMRNEILDKLARSGIFLASELEDFERLLLRLSRIGGVMQDSLPVQSYKSRAGCDFHSRFILYCLEHGLQHLLYTYLDYYKLSPGNCPFLEKKELHEAHPWLEFLVQCRQVSSNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGHTLLALATTMYAPGGVSQVIQNEDSENCLKKVDPQLLKVALTPYPKLKAALFPQYTAPSILPSDITLYHLIQSLPPFDPSRLFVWQSANTLAIGDTGSQLPHFSSPDLVSKYAVLERLNYAYYLHHGRPSFAFGTFLVQELIKSKTPKQLIQQVGKEAYTLGLSSFTNPSVGAACVCFLELLGLSSLKLRVDLKMANVILGSKRRDEDARSSFIRESLAEKLSKLADGDRAATEELLVLLEEGVWDSIEQQGFSRLSSESSSQWALVLQFCMLHDRK-LSVSYLRECAKANDWLQFLVHSQLHNYHPAEVESLLQYFSPVLQSHLKLASEKLSSGSISRDDS------CLQELQKNKGETSNFFEILHRCSDESTSWSWLLAEAVRHRAPILSVLASCVQGASVVSCLCVWIVTSVEDKVAAEAMGHIQISVEDHHWSLKDLSIIWRTVLTRRKSHTLIRGFQLFIKDSPLLLIMEMYELCMFFKNYEKAKVKLLEFQKSLETLDTVAARVLPIIPASWMKDQVCFLLKLMPQQCETQYELGKLLQLFVGTEQLFSDGPDVQKLCLLSQVLKDTPIAISPAVISSYSTENFQRECRSILEKLKADGQFAVARRVAELAALPVDSLLIEQLTQEMQTLTHTPQWSLKQERLGFWKKCHEIFKKNSISKRAASSFFSSQAPEVSEHPAEQGSLEERHLLLTLAGHWLAQEEPVPVEELEGLEKQIWICRVAQHTCGGAEEEAKPSLSQHKLAAAELSFDSLASELSFSKLAALNTSKYLGLNDLPSKTTCENRLKHKEQESLNTLIGQLLDGGCVHEASRVCQYFRFYSQDLVLVLHCRALASAEATMEDLHSEIRALLSSAAQPEDLESPSVPLRKAHSSSSLDSQSFVMVPPTDEVAQNLHTLISKCLHGKNYCRQVLCLYELAKDLGCSYGDVAARDSEAMLRAILASQRPDRCRQAQVFINTQGLEADTVAELVAEEVTRELLTPSEGTGEKQPFNPAEESQTFLQLTALCQDRTLVGMKLLDKIPSVPHG--ELSCTTELLILAHHCFTFTCHMEGITRVLQAARMLTDNHLAPNEEYGLVVRLLTGIGRYNEMTYIFDLLHQKHYFEVLMRKK-LDPTGTLKTALLDYIKRCRPGDS-EKHNMIALCFSMCREIGENHEAAACIQLKLIESQPWEES-LKDGAQLKQLLLKALTLMLDAAESYAKDSCVRQALHCNRLTKLITLQIHFLNSGQNTMLINLGHQKLMDCIMTLPR------------FYQASIVAEAYDFVPDWAEVLYQQVILKGDFSYLEEFKQQKLLRPNIFEDISKKYKQHQPTDRVTEN----LKKLLSYCEDIYLYYKLAYEHKFFEIVNMLLKDPQTGCCLKDMLAG---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JI7-1", "uniprot_id": "SPTCS_HUMAN", "id": "Q96JI7-1", "name": "Spatacsin", "aln": "-------------------------------------MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRG-ILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRNVEELIPALDLLCSAIRESYSEPQS--KHFSEQLLNLTLSFLNNQIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTDAIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRIDSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVKGQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLYLGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFNKQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTARHDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNNYMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNYKTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLEKKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDPQLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSRLFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYLHNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSIGAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFIRESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESSSQWALVVQFCRLHNMK-LSISYLRECAKANDWLQFIIHSQLHNYHPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQELQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVLASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDLSVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFRNYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLMLQQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTSIAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPVDNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSISSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVPLDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELSFDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNFLIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEASMEDLHPEIHALLQSAELLE-EEAPDIPLRRVHSTSSLDSQKFVTVPSSNEVVTNLEVLTSKCLHGKNYCRQVLCLYDLAKELGCSYTDVAAQDGEAMLRKILASQQPDRCKRAQAFISTQGLKPDTVAELVAEEVTRELLTSSQGTGHKQMFNPTEESQTFLQLTTLCQDRTLVGMKLLDKISSVPHG--ELSCTTELLILAHHCFTLTCHMEGIIRVLQAAHMLTDNHLAPSEEYGLVVRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKK-LDPSGTLKTALLDYIKRCRPGDS-EKHNMIALCFSMCREIGENHEAAARIQLKLIESQPWEDS-LKDGHQLKQLLLKALTLMLDAAESYAKDSCVRQAQHCQRLTKLITLQIHFLNTGQNTMLINLGRHKLMDCILALPR------------FYQASIVAEAYDFVPDWAEILYQQVILKGDFNYLEEFKQQRLLKSSIFEEISKKYKQHQPTDMVMEN----LKKLLTYCEDVYLYYKLAYEHKFYEIVNVLLKDPQTGCCLKDMLAG---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W1Y8-1", "uniprot_id": "Q9W1Y8_DROME", "id": "Q9W1Y8-1", "name": "Spatacsin C-terminal domain-containing protein", "aln": "----------------------------------------------------------------MHSAQAQAQARDKIFKNWRGISEVTIIKEVATKG--EHIDLCMEYWAQKRKIPVSEYRHYFYDVVQAY------------------------------------------VQRLLSERLVCKAEDVIRNVDRD--------VKCFFFQFACECQD--------------EELSEFVLDHLRSREPLMYEQEEPVLAYHWSLVQQLRECEALVAKHRTQLP--------------------RVHIEAMMTLPEQALQLLLVELYFANGNESLLGSLSKDMVWQHLVDSDEQ---------------AKLQRWCRLQEEGFVSQETLSPLEQSFTAWKIDATMYEYAVEELQQPSEVLRNFFAR----AGYFFMDESE---------------------------------------------------DIPSLLRRLCTMECLGKHADLLSRQPLAKYLLDRGQYSLLL----------------------------MECVPIASLELLAGTETHQEPLINLIVDIKTNSLTENE-------------------------GFELISKSVQAYLEKTHDTVDSFEGHPLLTFYDFLGQEPSVRSLEGFLTSTNLGR--------VPYLKSLIARFDHGP---------------------------------TSCNFGLPTAHDLFMKFKHVNLPLLATAGHGELVCFSNARLSQRYARKSQLNYTHYLKQQRSAYAVYYLITEQL-QLYGQITKTQLFHACETVTQIALQHAGDDELVTHCVACCEMLGFDTQPLRSFLLLQRKLPKCETGQSYSELLGEWDRDLVEMLEANPSEFPLELYQSLMRLAIRDTPGKLPMDLLKRYASKNNWWHLLLVFQFFDLPLS-----------------ELKKLLPHFKSSPIGVHLLRALSYESSGDRHHKRTLQRPTRRSGETQTNSSQETMTNSS--------------------------------------------------------HSSNQDSSVQQLQRNTDQSLCTLLTHTARQDVFAIILCSTNSLPDELIATTPKFLEMMVGNSSHCSSINLLR-HCIRQELPILAVLAATIS-------------------------EQNRDWCWIVWLSVASGQWSLQLQEAS------KVRDENRSEWVWSVIRG----------------------AVAGGHLNALLHSLEIFHPDCKLTHLCRFLQLTGHQEDFSDATIVELRQFFFSWSQDS------VALPLCGPLPRKQLMQRSIGLLLIQLQSNFDCILQQQRFLECICRSDVGDICDLLDFCLLHKVFGVAATWLRELSIDLEQLGRRDSPEYKRLVDALTEARAYEEALQLATLLQLPLTDIVYG------------------------------------------KWMTELEAGQLRPHEEYEKDIQQHALAPAILVNFLLQAAS-----------------------------------VVGQVSLRRYELLQSTLGVIKKHHLFPNESFDRDQIEYDMVLCYLQLPEEQLPQLSIYHS------------EYFEQIMLQERCVLYKSFSELKELAGIDDLS---------------------IADKTVLTSEMEDRLN----TLLNTLLDKGDIVEALRLQELFEFRPN--------------------------------------------------------------------DLRFIVFAMA-------------LAEGMTSISNLSSKERQLLGEIEKSAFPKFNRITLN------QNVITRWDSDLSDTCSDSVAMEFEEIPSK---------EKQQTLDTLLGIGSKLKYGVELG-----------RRIVLAYRAAMYLDKEYLDVLRTKDTGILLKSAAAEDCLQRLLVVSDIQISTRMTP---------KEIAECLALELTTCIVRPRFY---------------------IFHAREQPRNALRNADLWGHSIDRDFHLFLELAPNSTMLGNCLLEYCDALKTYRRYQEGKPFEETEAFENLSKIITLYGLPTPSPTGTMSGIPQVLSHKKQNQIYVELLIKAHLCFVHECSMEGIVSVLQKAKALNT-KLAQAKSWSLIVRLLIGIARYREMFYCFDSLIENEQFESLLGQFDEDQKGGLRQAILSYLREYQPKNGKELLRLAALHFLMYKELAEMWTTEAQEIVTKIQAFAAQSNKLKCSVEVQTLLQQALENYTHATENYLLDNKLLLAQQSVSRAELMAMQLDLCNKALEKRHSNNANHLCVSVIGVRSREQFRELVNVHLSVPQALILSRAYGYDISWSEAILSQFVVLQGVNYLQEYLCHQRINDDVIEQIVKGYLLHIQSNATNSKQEESMVQLVGLIKSVVLKYKLASILGFKSIVMSLINDSSVYYLRDTNFGRTDFHTAGDT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . *: :: . : : : .::: * : :.* . . : ::::: : :*:* .:: :. : :* :. . .*...:. :: : : ::* .. ::: . : :. :. ... :* : : :.: ::: .. *: * * : : .. * :*: : . **: :::* : * .: . * * * . :: : : *. ::.. * * * . :.: *: : : :: .* . * *. * : * :*: .*. * ** *.:* :::::. * * :. .. .::*:..::: .:.:. . * : * .**.:: . . :: : : *:::: :* : * :* *: :* * * * : *.. : .. . *. : : . :* ::: :: :* * : .: : : : * : * .* ::. :::* : : : . : : * : : * *:: .: . * * : ::::: : * : *: : : . . . * :* * : :* ...: * * :* .* * . :. . :. .: : :* ::. : . : * : .* :::* . . *. :* :. :: :.. ..:: : : :: *. . * ::: : .* : * ::* *: :* . * * :: .:.: : .* : :* .*. * . : **:* * .. . : . .: ::. : .:. *.: ::: *: * .: :*: :. :. .. .: . :::** **. :: ::*** : : * .: :. .:: : : *:*. .: *: . : * . . * * . . * ::: :.. :. :* :.*: . :: .:: * :: : . * :* . * * : :: ::* *: . *: . *: :. :.* . ::::* : :: ::*: * .*::. * *: ** : : : *.:::::* * : . :. :: * ::.: * :.: :. :. . . : . * : :: :*** .:*::*: *:* . * . :: : *: : :: *:.: .:* .: * : : : :: : . .*:. * : *: : ... * * . : * * .::. . : *.. . . : *: :* :.: :: :* * :. *..* : . .**** ** **. * **** *** *: *. :** :.:.*:**** **.**.** * ** * ::. ** *: : * .* *: *:*.*::. :* :. * .: ** * * :*:.* : * :. *:: . :.. ** . ::: ** :** .*:*.* *. : * :. ::*:::*:.: *.. :. * ..: :. * . .* . ** *::.**.: .*:* : .*.:: ...**:*: :: :. .::*:* * * * :: . .: : :*: :.: * **** * .** *::*... . :. ", "identical_positions": 272, "similar_positions": 634, "identity": "10.82%" }, { "cls_id": "homologset.agr.MGI:2444990", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V8D7-1", "uniprot_id": "G3V8D7_RAT", "id": "G3V8D7-1", "name": "Gap junction protein", "aln": "MENLNLLGFLFITLNCNVTIMGMLWLIVAVLLRMLVVVLAGSPIYEDEQERFICNTLQPGCANVCYDLFSPVSPLRFWLVQSLALLLPSVVFGTYTLHRSTKLAAAA-ACRP------------------------------QVPDLSSAYLVHLLLRMLLEAGLAFLHYFLFGFSVPAHVSCSRVPCSGAVDCYVSRPTEKSLLMLFFWAVSALSFLLSLVDLLCSLPKR--------------TLRTTQWVKGEARAGCEVPAPSPCLLQDPQGYHSQGQVDQEAR------QEEQVVPEFS-VWTAGQGGNSKAGQVSASGLLEHSDQ-----DVSEVTSSAGDRLAVAQTPHEFRSYRETSPDLGSKNTRSDALSLATQSHLARHCSASQPQAPGRLTT----SGSAPHLRTKKSEWV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BSD4-1", "uniprot_id": "CXD4_MOUSE", "id": "Q8BSD4-1", "name": "Gap junction delta-4 protein", "aln": "MEKLNLLGFLIITLNCNVTIMGMIWLIVEVLLRMLVVVLAGSPIYEDEQERFICNTLQPGCANVCYDLFSPVSPLRFWLVQSLALLLPSVVFGTYTLHRGAKLAAVGGACRP------------------------------QVPDLSTAYLVHLLLRMLLEAGLAFLHYFLFGFSVPARVSCSHVPCSGAVDCYVSRPTEKSLLILFFWAVSALSFLLSLADLLWILPRRK-------------TLRTTQWVNGEARPVCEVPAPPPCLLQNPQGYLSQGQVDQEDR------QEEQVVPEFPCMWTAGQSDNSNVGQACVSGLLEHSDQ-----DASEATSSAGDRLTVAHTAHELRFHRETSLDLGGKNTQADELSLATQSHLARHSSASKPQAPCRLTT----SGSAPHLRTKKSEWV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KN9-1", "uniprot_id": "CXD4_HUMAN", "id": "Q96KN9-1", "name": "Gap junction delta-4 protein", "aln": "MEGVDLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREP--------ASGQRRCPRPFGERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRR------------------------MRRRPGPPTSPSIRKQSGASGHAEGRRTDEEGG------REEEGAPAPPGARAGGEGAGSPRRTSRVSGHTKIPDE-----DESEVTSSASEKLGRQPRG---RPHREAAQDP--RGSGSEEQPSAAPSRLAAPPSCSSLQPPDPPAS----SSGAPHLRARKSEWV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXR7-1", "uniprot_id": "A0A8M9PXR7_DANRE", "id": "A0A8M9PXR7-1", "name": "Gap junction protein", "aln": "MAKQATSEVIFITLNHNITLTGKAWLVLVVFLRILVLLFAGYPLYQDEQERFVCNTIQPGCANVCYDMFAPLSLFRFWLVQLTTLCLPYIMFIIYVIHKVSSGLATDTGTSESIKADSIYKIHQESFRKASLCKMVMKAEKGRVQYFTGAYILHLLLRIMVEAGFGAAHYYLFGFHIPRRFMCQQAPCTTMVDCYISRPTEKTVMLNFMLGAAALSLLLNICDLICAIKRSVRQKNKRKMLVQKMYAEEQYYVSGNGNQGVDASSPPNQDVMSPGVFRKRGTRNSSGDEAASVLLDDDPPPSLPQEGKPTISGMPGCRSNDDSSSYQPTQEGGMVREGSEVALCPSEPLGTPRSIRVSKRSRLKPPPPPRRDKLAVQGAIDGSGATALCTRRVGQYTLVEMTTGEDITTCGGDGKEKKSEWV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .::**** *:*: * *::: ::**:**:::** *:*:******:***:**********:*:*:* :****:* : ** :* *.:*: :. * :* :: .*::***** ::**.:. **:**** * :. * : **: ****:******:::: *: ..:***:**.: **: : : . .:*. .. . . :.. ::: * . . . *. : .:: : **.: ...: * : * . :.. : . . * . :: : . . : :*****", "identical_positions": 100, "similar_positions": 106, "identity": "23.7%" }, { "cls_id": "homologset.agr.MGI:2444993", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1U7-1", "uniprot_id": "D4A1U7_RAT", "id": "D4A1U7-1", "name": "", "aln": "-----------MFRS-TRTTDQWRAGERLQCPAGHARAALARTADGGAVGPFKCVFVGEMAAQVGAVRVVRAVAAQEEPDKEGKEKPHVGVSPRG----VKRQRRVSSGGSQEKRGRPSQDPPLAPPHRRRRSRQHPGPLPPTNAAPTVPGPVEPLLLPPPPPPSLAPAGPAVAAPLPAPGTSALFTFSPLTVSAAGPKHKGHKERHKHHHHRGSDGDPVA-CVPGDLKHKDKQENGERSGGVPLMKAPKRETADENGKTQRADDFVLKKIKKKKKKKHREDMRGRRLKMYNKEVQTVCAGLTR-------------------------------------------------------------------ISKEILTQGQLNSTSG-------VNKESFRYLKDEQLCRLNLGMQEYR-------------VPQGVQTPFTTHQEHSIRRNFLKTG---------------------------------------------------------------------------TKFSNFIHEEHQSNGGALVLHAYMDELSFLSPMEMERFSEEFLALTFSENEKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKK-DIETTTISNFHTQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKMTLPWGTLSSLQLQCRSQSDDGPIMWVRPGEQMIPTADMP-KSPFKRRRS-MNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVICFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHP---------------------------------------------------------------------------VVETAQNTESNSNMDCG--------------------------------------------------------------------------------------------LEVDSQCVRIKTESEERCTEMQLLTTASSSFPLPSELHLQ-------------------DLKTQPIPVFKVESRLDSDQQHSLQAHPSTPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80T69-1", "uniprot_id": "RSBN1_MOUSE", "id": "Q80T69-1", "name": "Lysine-specific demethylase 9", "aln": "-----------MFRS-TRTTDQWRVGERLQCPAGHARAALARTADGGAVGPFKCVFVGEMAAQVGAVRVVRAVAAQEEPDKEGKEKPHVGVSPRG----VKRQRRASSGGSQEKRGRPSQDPPLAPPHRRRRSRQHPGPLPPTNAAPTVPGPVEPLLLPPPPPPSLAPAGPTVAAPLPAPGTSALFTFSPLTVSAAGPKHKGHKERHKHHHHRGSDGDPGA-CVPGDLKHKDKQENGERSGGVPLIKAPKRETADENGKTQRADDFVLKKIKKKKKKKHREDMRGRRLKMYNKEVQTVCAGLTR-------------------------------------------------------------------ISKEILTQGQLNSTSG-------VNKESFRYLKDEQLCRLNLGMQEYR-------------VPQGVQTPFTTHQEHSIRRNFLKTG---------------------------------------------------------------------------TKFSNFIHEEHQSNGGALVLHAYMDELSFLSPMEMERFSEEFLALTFSENEKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKK-DIETTTISNFHTQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKMTLPWGTLSSLQLQCRSQSDDGPIMWVRPGEQMIPTADMP-KSPFKRRRS-MNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVICFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHP---------------------------------------------------------------------------VVETAQNTESNSNMDCG--------------------------------------------------------------------------------------------LEVDSQCVRIKTESEERCTEMQLLTTASPSFPPPSELHLQ-------------------DLKTQPLPVFKVESRLDSDQQHSLQAHPSTPV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VWQ0-1", "uniprot_id": "RSBN1_HUMAN", "id": "Q5VWQ0-1", "name": "Lysine-specific demethylase 9", "aln": "-----------MFISGRRTADKWRAEERLQCPAGSARAALARCADGGAVGPFKCVFVGEMAAQVGAVRVVRAVAAQEEPDKEGKEKPHAGVSPRG----VKRQRRSSSGGSQEKRGRPSQEPPLAPPHRRRRSRQHPGPLPPTNAAPTVPGPVEPLLLPPPPPPSLAPAGPAVAAPLPAPSTSALFTFSPLTVSAAGPKHKGHKERHKHHHHRGPDGDPSS-CGT-DLKHKDKQENGERTGGVPLIKAPKRETPDENGKTQRADDFVLKKIKKKKKKKHREDMRGRRLKMYNKEVQTVCAGLTR-------------------------------------------------------------------ISKEILTQGQINSTSG-------LNKESFRYLKDEQLCRLNLGMQEYR-------------VPQGVQTPFMTHQEHSIRRNFLKTG---------------------------------------------------------------------------TKFSNFIHEEHQSNGGALVLHAYMDELSFLSPMEMERFSEEFLALTFSENEKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEILGKK-DIETTTISNFHTQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPFLKMTLPWGTLSSLRLQCRSQSDDGPIMWVRPGEQMIPTADMP-KSPFKRRRS-MNEIKNLQYLPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVICFHAEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHP---------------------------------------------------------------------------VVEATQNTESNSNMDCGLTGK--------------------------------------------------------------------------------------RELEVDSQCVRIKTESEEACTEIQLLTTASSSFPPASELNLQQ------------------DQKTQPIPVLKVESRLDSDQQHNLQEHSTTSV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B7YZX6-1", "uniprot_id": "B7YZX6_DROME", "id": "B7YZX6-1", "name": "Round spermatid basic protein 1-like protein", "aln": "MENTRGGENNVELANGGKESTGNVRKPEKKPLEGAVGASKQRETPEKGVNKASAVENNNANARGNASPTTTSAQREATTTITPVEPTAAATTTNGNTLPTQQQQQLQSGDGNANNPTTNARIMLAAAEEEQAVASSVATTAGAPTAATTTATTTALADTTKTSTSTDEKTGKVKRNSQNTNPMSTNVICTPTHSPTPPTEERNHKRKKRDRERDEDKNRRSNNHNSSSKDRDKDRDRDKERDKERDRERERDRNRESSSKSSKEAEHKSSSSRSKEKYHRSDRDREREKERDREKIPSSSSSSSSHSNRRRSSDSSRSSQNSSFKSKDPGADPVLPQAVVAALEKQIKVEEVIKKEPVETKQEVDTEPTPVLSNLIKTEAEIKTESTEKPNKPLVNGEAIAKTRDEVSRQLNFGDKVSNSKLMPSPAPKSSSGSNSTASNHSSSQSSSSRKSYLSSSSSSSSSNHHKSSSSSSSRHSSSTSRECSKCYKRSKIRRTSVGVQCLQHAPATGPWQTVQSLPPRPNRKPPAGLENLKYGCYFQVEQYPNGGASIVHLYQHEIDALSPDEMEELVDEFFEVCFAEDEQGYAHHVMGIVHDAARYLPDLLEHMAENYSTLTVKAGVLGRNSDIETCTMSQYNEQVVRNYCQGTFRYGPLHQISLVGKVHEEVGGYFPDLLGRIEMNPFLRKTMPWACNSILQTDPR-QSNDGPILWIRAGEQLVPTAELNSKTPLKRQRTRINELRNLQYLPRLSEARETMIEDRTKAHADHVGHGHERITTAAVGILKAVHCGQTYSQNRITKDVVAFAAQDFNTMVEMLQLDLHEPPISQCVQWIEDAKLNQLRREGVRYARIQLCDNDIYFLPRNIIHQFRTVTAVTSVAWHLRLRQYYPGQEVINEKNNPVLAETPHYKEKQTILPNPISHDECGKKTPSKRAHDGRTKKKLIDLDGKERRSSESSIDEHPAAGSSSPSQNQENNSNSSSQSGASGVSTPKKKSSKEDSKIDMRKMVLEHKYKLTKAAVTETPEKEKLKKDKDKEKSRGKDRDKEKERGKEKEKEKEKKNDTPKKHATPAKSSLSEPSPAKIPKLNNDTAPATALPLKSTPSSAPPTCTLPVAAPPILSGLPPPLVPQTPFIDRLNQKEPEIKIEVKIVSDSKSDISTSNPVVSTTAPPPPPPPDPVEDVGNELIVESTPQLIVDHEEEVSEVCSEEIVEMDIPIPKEPVPAAAFTSLPNTPSPLISAHSTLATAPIPKSFLHPPVPIVAAPAPPPPSQIVKVVLPGSLTPLTRMSVVLPPLPPLPPSRTSAPPPPPPPPSTKSSAITMPISAPVSTLKPTYKTINLPSHKIIIAGSAAGSRVSMAKGTSKRPDLLGSIIASMDKPAGSGPNSNSSSSTSSATTNSSLSSYAGSNNSF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 276, "similar_positions": 292, "identity": "19.62%" }, { "cls_id": "homologset.agr.MGI:2445001", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P69735-1", "uniprot_id": "RB3GP_RAT", "id": "P69735-1", "name": "Rab3 GTPase-activating protein catalytic subunit", "aln": "MAADSEPES----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVGCPLTPLPPVSIAIRFTYVLQDWQQYFWP---QQPPDIDALVGGEVGGLEFG---KLPFGACEDPISELHLATTWPHLTEGIIVDNDVYSDLDPVQAPHWSVRVRKADNPQCLLGDFVTEFLKICRRKESTDEILGRSTFEEEGR-VADITHALSKLTEP-APVPIHKLSVSNMVHTAKKKIRKHRG-EESPLNNDVLNTILLFLFPDAASEKPLDGTTSVDNSNPAAEAGDYTLYNQFKSAPSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFRWENNFLIPGLASGPPDLRCCLLHQKLQMLNCCIERKKARDEGKKTSPSDSMTKAYPADAGKAGGQLGLDHLRDTEKEKGEAGKSWDSWSDSEEEFFECLSDAEDLRGNGQESTKKGGPKDMAPLKPEGRLHQHGKLTLLRN-GEPLYIPVTQEPAPMTEDLLEEQSEVLAKLGTSAEGAHLRARMQSACLLSDMESFKAANPGCCLEDFVRWYSPRDYIEEEVTDEKGNVVLKGELSARMKIPSNMWVEAWETAKPVPARRQRRLFDDTREAEKVLHYLAMQKPADLARHLLPCVIHAAVLKVKEEES-LENIPSVKKIIKQIIAHSSKVLRFPSPEDKKLEEIILQITTVEAIIARARSLKAKFGTEKCEHEEEKED--LERFVSCLLEQPEVAVTGAGRGHAGRIIHKLFVNAQRAAAVALPEEELKRSGCPEERRQTLVSDFPPPAGRELILRATVPRPAPYSKALPQRMYSVLTKEDFRLAGAFSSDTSFF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UJ7-1", "uniprot_id": "RB3GP_MOUSE", "id": "Q80UJ7-1", "name": "Rab3 GTPase-activating protein catalytic subunit", "aln": "MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGPSLGKPLEKGIFTSGTWEERSDEISFADFRFSVTHHYLVQESPDKERKDEELEDAIPQS--MQDLLCMNNDFPPRA------HCLVRWYGLREFVVIAPA-AHSDAVLSESKCNLLLSSISIALGNTGCQVPLFVQIHHKWRRMYMGECQGPGVRTDFEMVHLRKVPSQYTHLSGLLDIFKSKIGCPLTPLPPVSIAIRLTYVLQDWQQYFWP---QQPPDIDALVGGEVGGLEFG---KLPFGACEDPISELHLATTWPHLTEGIIVDNDVYSDLDPVQAPHWSVRVRKADNPQCLLGDFVTEFLKICRRKESTDEILGRSTFEEEGREVADITHALSKLTEP-APVPIHKLSVSNMVHTAKKKIRKHRG-EESPLNSDVLNTILLFLFPDAVSEKPLDGTTSIDNSIPAPEAGDYTLYNQFKSAPSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFRWENNFLIPGLASGSPDLRCCLLHQKLQMLNCCIERKKARDEGKKTSLSDSTTSAYPGDAGKTGGQLGLDHLRDTEKEKGEVGKSWDSWSDSEEEFFECLSDTEDLKGNGQESGKKGGPKEMANLKPEGRLHQHGKLTLLHN-GEPLYIPVTQEPAPMTEDLLEEQSEVLAKLGTSAEGAHLRARMQSACLLSDMESFKAANPGCFLEDFVRWYSPRDYIEEEVTDEKGNVVLKGELSARMKIPSNMWVEAWETAKPVPARRQRRLFDDTREAEKVLHYLAMQKPADLARHLLPCVIHAAVLKVKEEES-LENIPSVKKIIKQIIAHSSKVLHFPNPEDKKLEEIILQITTVEAIIARARSLKAKFGTEKCEHEEEKEG--LERFVSCLLEQPEVSVTGAGRGHAGRIIHKLFVNAQRAAAVALPEEELKKSGCPEERRQTLVSDFPPPAGRELILRATVPRPAPYSKALPQRMYSVLTKEDFRLAGAFSSDTSFF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15042-1", "uniprot_id": "RB3GP_HUMAN", "id": "Q15042-1", "name": "Rab3 GTPase-activating protein catalytic subunit", "aln": "MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGNSLGKPLEKGIFTSGTWEEKSDEISFADFKFSVTHHYLVQESTDKEGKDELLEDVVPQS--MQDLLGMNNDFPPRA------HCLVRWYGLREFVVIAPA-AHSDAVLSESKCNLLLSSVSIALGNTGCQVPLFVQIHHKWRRMYVGECQGPGVRTDFEMVHLRKVPNQYTHLSGLLDIFKSKIGCPLTPLPPVSIAIRFTYVLQDWQQYFWP---QQPPDIDALVGGEVGGLEFG---KLPFGACEDPISELHLATTWPHLTEGIIVDNDVYSDLDPIQAPHWSVRVRKAENPQCLLGDFVTEFFKICRRKESTDEILGRSAFEEEGKETADITHALSKLTEP-ASVPIHKLSVSNMVHTAKKKIRKHRGVEESPLNNDVLNTILLFLFPDAVSEKPLDGTTSTDNNNPPSESEDYNLYNQFKSAPSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFRWENNFLIPGLASGPPDLRCCLLHQKLQMLNCCIERKKARDEGKKTSASD-VTNIYPGDAGKAGDQLVPDNLKETDKEKGEVGKSWDSWSDSEEEFFECLSDTEELKGNGQESGKKGGPKEMANLRPEGRLYQHGKLTLLHN-GEPLYIPVTQEPAPMTEDLLEEQSEVLAKLGTSAEGAHLRARMQSACLLSDMESFKAANPGCSLEDFVRWYSPRDYIEEEVIDEKGNVVLKGELSARMKIPSNMWVEAWETAKPIPARRQRRLFDDTREAEKVLHYLAIQKPADLARHLLPCVIHAAVLKVKEEES-LENISSVKKIIKQIISHSSKVLHFPNPEDKKLEEIIHQITNVEALIARARSLKAKFGTEKCEQEEEKED--LERFVSCLLEQPEVLVTGAGRGHAGRIIHKLFVNAQRAAAMTPPEEELKRMGSPEERRQNSVSDFPPPAGREFILRTTVPRPAPYSKALPQRMYSVLTKEDFRLAGAFSSDTSFF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NUV0-1", "uniprot_id": "RB3GP_DANRE", "id": "Q6NUV0-1", "name": "Rab3 GTPase-activating protein catalytic subunit", "aln": "MAADSDPESEVFEITDFTTASEWERFISRVEEVLNDWKLIGSRVGKPLEKGEYTSGTWEESSQEISFADFKFSITHHYLKQESAENDGRDELEEDAYPLA--MQDLLCINNDFPPRA------HCLVRWFGVREFVVISPG-ANCEAIISESKCSLLLSSVSIALANTGCQVPLFVQIQQKHRKMFSGECQGPGVRSDFEMVHLRRVPSQYNHLSGLLDIFKNKIGCPLTPLPPINISIRFTYVLQDWQQCSWP---QQPPDFDALLAGEVGGVEFG---KLPFGACEDPISELHLAATWPSLTEGIVVDNDVYSDLDPLQAPHWSVRVRTAENPQCLLGEFLTEFFKICCRKETTEEILGRSTAEEEGKENSDITQALSKLTEPSTAVPIHKLSVSSMVHSARKRIRRHRRVPESPLNNDVLNSILLYLFPDAALDKADVSEVRPPQQSPDRQSEDYHLYNQLKSCPSDSLTHRLALCICMVNFHHGGVRAVAHLWQEFVLEMRYRWENNCLIYGLASGPPDLRCCLLHQKLQMLNCCIERKKARDDGKKSSSSDGARDRSRGAPEGAG--------PEGAGPAEAAGKSWDSWSDSEDEFFECVSDTEEMKEDKEEAENRSRSK------PEGRLQPHGTHTLLNT-QEPLYIPITQEPAPMTEDLLEEQSEVLAKLGTSAEGAHLRARMQSACLLSDMESFKAANPGCTLLDFVRWYSPRDYVEEQVTDADGRVEVRGELSARMKIPGNMWVEAWETARATPARRQKRLFDDTKEAEKVLHYLALQKPSELTRHLLPCVLHAALLKIKEEES-AEDLPSVRSSLQQISSSASKILRHPNPEFKKLEDVISQLMAVEAVIARARSLKAKFGVCGGEREREEDGDELERFVSSLLEEPEVCVSGAGRGPAGNVIHKLFVSSQRAALLAPMEEETLRSGGSDDRK--AFPDFPPPAGREILLRTCVPRPAPYSKALPQRLFCVLMRDEFRLAGAFSSDTSFF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQ26-1", "uniprot_id": "RB3GP_DROME", "id": "Q9VQ26-1", "name": "Rab3 GTPase-activating protein catalytic subunit", "aln": "--MAEEIDDNEFYRENFSADSDWEVFNAQLGEILQKWDVSSDSETRNLKSEEIFSCNWKVEREKLDMLRNGIEVEYHQAILEDEELVRAEAKEITCLQRTSCHHDLMSTGNSFGPPIRSSQELHILARIYGLRRFIVLHPVNPTLNYMRSTSEFNFFLSAVAVVSAEVQSLVPIFVQIYDPKWNYYTGVALAPALRTNFRLIGLEKAPPECRFLMGLLTLFREKVPTSYTQAAMISVCTTYALDTMRIRMPMYVPFDHGLSSEDIVVDGEVSHLEVQQFCALPHGYKPESRTEIYLVYTWPELSEHVAFDSEQRSDFVPAKAPLGKIYLSVEASS----------YLSCCLRDYQSVAEVTRSLESFVGRNFSGTSSGAEAASNPLDRITEHKLTKRRERSFELPSQAGLTKRLPGPMTESELSELLAYLFPDMHPEMALFPYAKKNFTDKFDP-------MRIKSAVPDSLVCRLSCLLATCHAHLGSVEGMAQVWAAFTRQLRLLWDNSLMVPGISAGFPDTRTCLLHQKLQMLNVCVERRVQREANSKRKSEGMVGKASSEEE--------------------------EDEDDDEGEFFDCDDLTAGAG---------SPTKAVLSLKPEGRLRRLNNERLLEEPDEYLYIPDTQEPVPKTEDQLQDDAEVMLKLGP---GSGLTTQMMCTSLLSDMEAFKAANPRGIMEDFIRWYSPKD--WEEVTDELG--QVKHQLSIRMTTEGNTWQKVWEQAQAVPVSRQKRLFDDTNEALKVLHYLETRKMHEIYNLTVIPLLHSAILKLADILSNAELEDLFSSQIEKLLSDLCRLSRSHSDELPSIKPLLDDLAELERRFYQFKCFERLSGYPKRSS-----------LQQVKLQFEEILRNDNCCTIVNRRLTAAGDGTLYDILIPKLEEDMADRLISKDYIIRLDGDTKTTEKGLYLG--------------PQFMRAIVTGEKLRLCGAFTESTAFV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :. :: . * . :.:. : : : : .. * :: ***. :*. **.* :. :*::*. *** *:* : .*.: **: * :** .: : .. ::. * *. : : ** . *: :. : . . ::* :. ***: .*:... *. :* :**** : . . ::**. .***. :*: :. : : *.:..:*::* *. ::* *:*. :: *:::* ** * *********** *:**: *: ..* . .. . :. .*.* ***:* . : . .* ***** .. **. * **** ****.* *** *::::**: ***. *: * ::* .:.******:****** : **:*****:* *:* * * :: :** **. .* * :.** *:. *. **:******.** ****** :* :: . : ::*:*:**: : * * . . :::: : .:: : . * .:: :: :: :* : : :.:: * . : . *: *: .. ... : .: :. **: ..: * .. : ** : .:: :.:**.***:..*:*.", "identical_positions": 182, "similar_positions": 222, "identity": "18.16%" }, { "cls_id": "homologset.agr.MGI:2445003", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYR5-1", "uniprot_id": "A0A0G2JYR5_RAT", "id": "A0A0G2JYR5-1", "name": "", "aln": "-MSLKDRTGSLEVIAGSGRSTRKAMFGPGSKPEVGRRYGGSGWELRAPEGAVPIPTSEPDVCRALTGVAKGALPERGELQSAGSHWAWWLLFWFSLAMDPLSELQDDLTLDDTSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSS------------------SPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYT--------------LLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNYLSELSEHVKLEQLGIP---------RQVLKYDDFLKSTQKSPATAPKP------MPPRPPLPNQQFGVSLQHLREKNPNQEPIPIVLRETVAYLQAH-ALTAEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPA-VILKTFLRELPEPLLTFDLYPHIVGFLDLDDDQR-VEVTQQVLQTLPEE----------NYRVLHFLTAFLVQVSAHSYQNRMNNTN---LAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSTDAQGV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5FWK3-1", "uniprot_id": "RHG01_MOUSE", "id": "Q5FWK3-1", "name": "Rho GTPase-activating protein 1", "aln": "-------------------------------------------------------------------------------------------------MDPLSELQDDLTLDDTSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSS------------------SPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYT--------------LLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNYLSELSEHVKLEQLGIP---------RQVLKYDDFLKSTQKSPATAPKP------MPPRPPLPNQQFGVSLQHLQEKSPGQDPIPIVLRETVAYLQAH-ALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPA-VILKTFLRELPEPLLTFDLYPHVVGFLNIDESQR-VEVTQQVLQTLPEE----------NYQVLHFLTAFLVQISAHCDQNKMTNTN---LAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSTDAQGV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07960-1", "uniprot_id": "RHG01_HUMAN", "id": "Q07960-1", "name": "Rho GTPase-activating protein 1", "aln": "-------------------------------------------------------------------------------------------------MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPDFPKSDDSKSS------------------SPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYT--------------LLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIP---------RQVLKYDDFLKSTQKSPATAPKP------MPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAH-ALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPA-VILKTFLRELPEPLLTFDLYPHVVGFLNIDESQR-VPATLQVLQTLPEE----------NYQVLRFLTAFLVQISAHSDQNKMTNTN---LAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDPSGL----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VTU3-1", "uniprot_id": "RG68F_DROME", "id": "Q9VTU3-1", "name": "Rho GTPase-activating protein 68F", "aln": "------------------------------------------------------MDAHSRFAPRLPGPAINPIVDNSDEPQP--------------SLSDLHDFEPKLEFDDTELLAPSPLEKDVMVGDFVLAEDPELEPEEDVNPL------------------EDDFEDQLREQSENFQTPRNK-CDFLGTDKQGRHIFGIYASRFPEKSQLEG--FVREIIKEIEPFVENDYI--------------LVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSLDELRQALGLNKLKLP---------DNICDLDDKLNPSRKPSTPPPSSNINASRQQQHKMATTHQFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSVN-VHVIA-GLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREKLPEE----------NYELFKYIVEFLVRVMDCEDLNKMTSSN---LAIVFGPNFLWSRSTSTSLEEIAPINAFVDFVLQNHKDIYLIDVNQRTVSVD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32525-1", "uniprot_id": "ECM25_YEAST", "id": "P32525-1", "name": "Protein ECM25", "aln": "MIDINVNNIFFRSYSVDPNSGHAIYVFDSTYLPASDEIGDKQVYDLLINALMDRLVMKLPQAPYSLVIFSSGFSQRKISWVYGIKMFAKLPKETKFYLQKIFIVHESFFVRSVYQVISNAMNFNFLDSKDSQHDFPSLVHVLDLTSLSELIDITRLRISLNVYLYDYQIREHINVPEEYYNRLTPLAIRQYRQLVFDKIFKKLQNDALLCELIFQKPGNYKKVNIFLDIIKRNNYIDLSQWDIYSLASVWLNYFIKNKAKPLIPIELIPLPIVDDLKFTSETFRKIIKFNQYQDLFMVIIPFFNRIIAHGESTKHDSRTLSKALTPALCKEKLSMMTNDRLAIGSRYIKNLLDFFPEIAKEISSPPSS-VSSSSTIPVLPKPRKSSPTRYSELGCLTLPRSRSPSPQRSVTSPTYTPVALQNTPVLKPKSSSRNVSSPSFNAKPPLPIKAVTRPQLSLTSNSNTDLALASSSTDTLSSPTKTPSADSLPLSNSSTDLTISDNIKEMVKDEPAKDKNSVETDIFVQQFESLTLVQNAKIKKFDKELQEKKKKNETTSKTADKFSQKGYSDIKASNKVSRLAALYEERLQGLQVMNEMKQRW---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : .. .: . .. . .. . : *.: * .. . : ::. . :: .: : : : . :: : :: ..:* * *: :. . * ::. . .. * : . : :: .: :*. :*: * . . * : ::* : : . * : * :..*.. . :. . . : . . * *. . .: ::: ... : . . : :. : : : . * . . *: .. * ... : : : : :* : : :: **: :: . : . . :::. :: :. :. : :. : . ", "identical_positions": 23, "similar_positions": 143, "identity": "3.81%" }, { "cls_id": "homologset.agr.MGI:2445010", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AB99-1", "uniprot_id": "D4AB99_RAT", "id": "D4AB99-1", "name": "Pecanex-like protein", "aln": "MASQVLQLLRQGVWAALTGGWYHDPEHSKFTNSCHLYLWLFLLLLPLALHLAFPPNLLTALFYCGSVTIFFTVIKLISYRLHLMFDKGEVIQHRSPR-------KRSKRRPEGEASSQHPPRHKIPSNNRQIHSTKKEESR-SLTTPPLCCSSRGQSVHSQHSSGP-------------------------------------------------------LELPAQETVEDLKGVVLSEDQPEALVSSTSPGMKSESLPASQGRTPEPTPRPPCPVKPVTTEIFPA-RRVKESGGTAQRPARHRSESGLVNTEALKKLPHLSLSQYDLLETDISFQPWGSEHSVLIPQPN---------CPHAPTRAQPQSRSPQDSQSSSFCQCNTVIAKPTEEELTR-----TSGQVELPSNPEVVDSDGEVEVTLIDTSQPGEPLSLHEPIRIVITMSSTPNSISDPESSLHLRVTSSDRTGVRPNAENAGPGGADPADPEQ-----------------------------------ARIPLITLELTEDGRGGGGPSCPEGNGGERTPEKMEV-MSPDRRSSSGVGECS---------TKDESPTPG----------------------PTFVPLTPRADP-ESEGSRE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPANLDPASCKSSHEKR-HARVLSVDSGTDVFLSRSTKEVVSDSEKPIPTSKSDLEAKE---------------------------------------GQIPNESNFLEFVSLLESISTSKAVAP---DSAAEQKGVNQGPEGHASPGIKEEAVENEK----------------SNGRDPKPGKPDLPSQDPASASPVLTQPPKTTALFQGSRQRHIIYR-----VTSQQDSSVLQVISGPETSVQEEMSLDAMHIFIDEHGEVRSCYLKSGNQKEGSSQHPPLNPDCVSHAREILLSSSSTTTTGSPDPSSGDPAVSALQQQLLLMVARRTQSETPRHVSQD--LEDSSR----------------------------------------------------SSAQGKFNREQFYKFIIFPG---KWIKVWYDRLTLLALLDRTEDVKENMVAVLLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSLLKSVQPDPASPIHGHNQIIAYSRPIYFCMLCGLILLLD---AGAKARHPPSYVVYGLKLFTPETLQSVRDHLIVFLCCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAVSGITSAVYSVGRSVLAAALLHVFCFSAVKEPWSTQHIPALFSAFCGLLVALSYHLSRQSSDPSVLLSFIQCKLLPKCLHQNLDES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AADPLPQRMKDSVKDVLRSDLIICSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLITHHLLPQLRKHHPWMWISHPVLKSKEYQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNAVTLDAFSISNYRRLGTHWDIFLMITAGMKLLRTSFCNPVHQFANLGFTVVFFHFDYKDVSESFLLDFFMVSIVFTKLGDLLQKLQFVLAYVAPWQMAWGSSFHVFAQLFAIPPKKHKCIVKEPWSQFNVGTTDPQHFTADDTSCQCLCSVTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTQRVDNSNTRLAVQMERDPGSDDGSLNSIFYEHLTRTLQDSLCGDLALGRWGNYSSGDCFILASDDLNAFVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTWEITRTQYILEGYSIIDNNAATMLHVFDLRRVLIRYYIKSIIYYMVTSPKLASWVKNESLLKSLEPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCSVFLEWIQYCAGKR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------QELSKTLDHVDSDEDSALVTLSFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVT-ARDEWVFADMDLLHKVVVPAIRMSLKLHQDQFTCPDEYEDPEILYEAIQSFEKKVVICHEGDPAWRGAVLSNKEELLTLRHVVDEGANEYKVIMLHRGFLSFKVIKVNKECVRGLWAGQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQSVWGGPITLNRVRTWFQTRWLRMRKDCSVGQRSGG-NIEDGEGAVPP---GGNAPSGESRDSSTEQPRKGGTQQWASPRGEAPRAG---------------------------------------------------------------------------------------------RRKGRSQSVQAHSAISQRRPTLSSSGPILESHQAFLQTSTSV----------------HELAQRPSGSRPSLNTS-AGSLHSQPPPVLTTGPYLGIQHQAEALIQSSLGSSTSSTLSFLFGK-------------------------------------------------------------------------------------------------------------------------------------RSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAA---ARHFSEPCEPI-------------------------------------------------DSPEQGQLQDGRLAEAAGENPRGVLCRRASQEDMGLDDTASQQSTSDEQ-----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DU28-1", "uniprot_id": "PCX2_MOUSE", "id": "Q5DU28-1", "name": "Pecanex-like protein 2", "aln": "MASQVLQLLRQGVWAALTGGWYHDPEHSKFTNSCHLYLWLFLLLLPLALHLAFPPNVLTALFYCGSVTIFFAVIKLISYRLHLMFDKGEAIQHRSPR-------KRSKRKPEGEASSQHTARHKNPSNNRQIHSTKKEEPRGSLTTPPLCCSSRGQSVHSQHSSGP-------------------------------------------------------LELPAQETVEDLKGVVLSEDQPEALASSTSPGMKSESLPASQGRTPEPTPRPACPLKPVTTELFTA-RKGKESGGTAQRPARHRSESGLVNPGALKKLPQLSLSQYDLLETDISFQPWGSEHSVLLPQPN---------CTQGATRAQPQNRSPQDSLSSSCCQCNTVLAKPTEEELTR-----TSGQVELPLNQEVVDSDGEVAVTLIDTSQPGEPLSLHEPIKIVITMSSTQNSISDLESSLHLRVTSSDRTSVRSSAESAGSGGAGPADPEQ-----------------------------------VRIPLITLELTEDG-GGRGVSCSEGNGGERTPERMEV-MSPDRCSGSGPGDG--------------SPTPG----------------------STLATLTPRVDP-ESEGSKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQANLDPASCKSSHEKR-HARVLSVDSGTDVFLSRSTKEVVSDGEKPIPTSKSDLEAKE---------------------------------------GQIPNESNFLEFVSLLESISTSKVVAP---DSPAEQKGASQGPEGHASPGTKEEAVENEK----------------PNGRDPKPGKPDLPSQDPANGSPVFTQPAKSAALFQGSRQRHIIYR-----VTSQQDSSVLQVISGPETSVQEEMSLDAMHVFIDEHGEVRSCYLKSGNQKEGSSQHPPLNPDCVSHARGILLSSSSSTATGSPDPSSGDPAVSALQQQLLLMVARRTQSETPRHVSQD--LEDSSR----------------------------------------------------SSAQGKFNREQFYKFIVFPG---KWIKVWYDRLTLLALLDRTEDVKENMVAVLLSVLVSLLGFLTLNRGFCRDLWVLLFCLVMASCQYSLLKSVQPDPASPIHGHNQIIAYSRPIYFCMLCSLILLLD---AGAKAKHPPSYVVYGLKLFTPETLQAVRDHLIVFLCCFPAISLLGLFPQINTFCTYLLEQIDMLLFGGSAVSGITSAVYSVGRSVLAAALLHAFCFSAVKEPWSTQHIPALFSAFCGLLVALSYHLSRQSSDPSVLLSFIQCKLLPKCLHQNLEES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATDPLPQRMKDSVKDVLRSDLVICSAAAVLSFAVSASTVFLSLRPFLSIVLFALAGTVGLITHHLLPQLRKHHPWMWISHPVLRSKEYQQREARDIAHLMWFERLYVWLQCFEKYLLYPAIVLNALTLDAFSISNYRRLGTHWDIFLMITAGMKLLRTSFCNPVHQFANLGFTVIFFHFDYKDISESFLLDFFMVSIVFTKLGDLLQKLQFVLAYVAPWQMAWGSSFHVFAQLFAIP------------------------------HSAMLFFQTFATSIFSTPLSPFLGSVIFITSYVRPVKFWERSYNTRRMDNSNTRLAVQMERDPGSDDNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAIMEGDEDDRGCCCCKPGHLPHLLSCNAAFHLRWLTWEITRTQYILEGYSIIDNNAATMLQVYDLRRVLIRYYVKSIIYYMVTSPKLVSWVKNESLLKSLQPFAKWHHIERDLAMFNINIDDDYVPCLQGITRASYCNVFLEWIQYCAGKR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------QELSKTLEHVDSDEDSALVTLAFALCILGRRALGTAAHNMAMSLDSFLYGLHALFKGDFRVT-ARDEWVFADMDLLHKVVVPAIRMSLKLHQDQFTCPDEYEDPAVLYEAIRSFAKKVVICHEGDPAWRGAMLSNKEELLTLRHVVDEGADEYKVIMLHRGFLSFKVIKVNKECVRGLWAGQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHKQLQSVWGGPVTLNRVRTWFQTRWLRMRKDCSVGQRSGGGNIEDGEGGAVPSAGGGSAPNGESRDGSTEQPRKGGTQQWSSPRGEAQRAG---------------------------------------------------------------------------------------------RRKGRSQSVQAHSAISQRPPTLSSSGPILESHQAFLQTSTSV----------------HELAQRPSGSRLSLHTS-AASLHSQPPPVTTTG-HLSVRERAEALIRSSLGSSTSSTLSFLFGK-------------------------------------------------------------------------------------------------------------------------------------RSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAAGHAARHFSEPCEPT-------------------------------------------------DSPEQGQLQDGRLAEAMEEN-LGVLCRRASQEDMGLDDTASQQSTSDEQ-----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NKB5-1", "uniprot_id": "PCX2_HUMAN", "id": "A6NKB5-1", "name": "Pecanex-like protein 2", "aln": "MVSQVLQLLRQGVWAALTGGWYHDPEQSKFTNSCHLYLWLFLLLLPLALHLAFPPNAIIVFFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSR-------KEEKPNKDKEAKGEHITNHRNPSNNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSGP-------------------------------------------------------LELSAQETVEDLKGVILLEDHPIAPVSSTSPGIKVESLPASQAHMLETTTKSVIPVKPVATETLIN-GKGKERGGKGQPPLRHRSEGGLVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLIPEPVS--------CPRGSIRERVQSKSPQDSLSSSCPQCDTIVAKPVEEPADTSCQVDTSCQGDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIKIVITMSSTPNSMTDLESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPNAEQ-----------------------------------ISIPVITLDLPEGG--GGGVPCPEGNGSERTPERLKTRVSTNQCSGYGSGEGGNAIKD----HSSSSREPW----------------------ESVSRLTPDTGS-ESKVGKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQTNLDPSSCKSSHEKR-HARVLSVDSGTDVFLSKSSAEIVNDTEKTMPTSKSDLEAKE---------------------------------------GQMPNESNFLEFVSLLESINTSKMTASSQLNGSAEQNEESGLLRDNCSQEKKEEILENEK----------------PSGHSSKQGKPDLQSQDHTSTGPACTQPAKTTAFFQGNRQRQIIYR-----VTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEHGEIRSCYLKSGNQKEGPLQPLPSNNDCLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVARRTQSETPRHVSQD--LEASSC----------------------------------------------------SSTQGKFNREQFYKFIIFPG---KWIKVWYDRLTLLALLDRTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSLLKSVQPDPASPIHGHNQIITYSRPIYFCVLCGLILLLD---TGAKARHPPSYVVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLFFGGSAVSGITSAVYSVARSVLAAALLHAVCFSAVKEPWSMQHIPALFSAFCGLLVALSYHLSRQSSDPSVLMSFIQCRLFPKFLHQNLAES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AADPLPKKMKDSVTDVLKWDLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVTHYVLPQLRKHHPWMWISHPILKNKEYHQREVRDVAHLMWFERLYVWLQCFEKYILYPALILNALTIDAFLISNHRRLGTHWDIFLMIIAGMKLLRTSFCNPVYQFINLSFTVIFFHFDYKDISESFLLDFFMVSILFSKLGDLLHKLQFVLTYVAPWQMAWGSSFHVFAQLFAIP------------------------------HSAMLFFQTIATSIFSTPLSPFLGSVIFITSYVRPVKFWEKNYNTRRVDNSNTRLAVQIERDPGNDDNNLNSIFYEHLTRTLQESLCGDLVLGRWGNYSSGDCFILASDDLNAFVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAIMEGDEEDRGCCCCKPGHLPHLLSCNAAFHLRWLTWEITQTQYILEGYSILDNNAATMLQVFDLRRILIRYYIKSIIYYMVTSPKLLSWIKNESLLKSLQPFAKWHYIERDLAMFNINIDDDYVPCLQGITRASFCNVYLEWIQHCARKR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------QEPSTTLD---SDEDSPLVTLSFALCTLGRRALGTAAHNMAISLDSFLYGLHVLFKGDFRIT-ARDEWVFADMDLLHKVVAPAIRMSLKLHQDQFTCPDEYEDPAVLYEAIQSFEKKVVICHEGDPAWRGAVLSNKEELLTLRHVVDEGADEYKVIMLHRSFLSFKVIKVNKECVRGLWAGQQQELIFLRNRNPERGSIQNNKQVLRNLINSSCDQPLGYPMYVSPLTTSYLGTHRQLKNIWGGPITLDRIRTWFWTKWVRMRKDCNARQHSGG-NIEDVDGGGAPTTGGNNAPSGGSQESSAEQPRKGGAQHGVSSCEGTQRTG---------------------------------------------------------------------------------------------RRKGRSQSVQAHSALSQRPPMLSSSGPILESRQTFLQTSTSV----------------HELAQRLSGSRLSLHAS-ATSLHSQPPPVTTTG-HLSVRERAEALIRSSLGSSTSSTLSFLFGK-------------------------------------------------------------------------------------------------------------------------------------RSFSSALVISGLSAAEGGNTSDTQSSSSVNIVMGPSARAASQATRHLSEPCEPP-------------------------------------------------DATEQGQLHDRCLAEAVADT-LGVVCRRASQEDMGLDDTASQQSVSDEQ-----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QI88-1", "uniprot_id": "A0A2R8QI88_DANRE", "id": "A0A2R8QI88-1", "name": "Pecanex-like protein", "aln": "MGSQVVQTLRQGVWASLTGGWYHDPDQNKFNNSCHLYLWMFLLMLPLSLHLALPPTTTTLSIYCTSVTLFFIVIKMINYRLHVMFDKGDIVAQNSVP-------DISKG-----------VDKKSNASDSCLPSLRK-----SSTVPDSVATS---VLTKNRPSPV-------------------------------------------------------IQVTVKQTETDPG---LIGECP-----------KSEELKNTEG----------------QSDVICN-DRSRPEAEEQLTPDDDVFSPNTDQSAPLLQGEQIPSAHRDKAEEDLPPTPTNEDD-----------------------------KPPTDPNNN-----NTSLEI--AENRER---------------PEENYCSDEIAVVLVDNSSPSVNLDESDTVKIIITMSCDPQTAAELEESVKQSILQSAQSHQGDSDCPVKIPVITFDSPHE-----------------------------------AEEPTAEDDEKDDTPIGGDNSVQEKSERQDSLLAKEP-ISSDSAQECKEIESNEQEMPNMSPLMTNNSSSG----------------------IDVNSHPDESDPPELKLDAD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFLQIPSAYMRCTQSGRTHARGLSIDSGRDAVLIS---YKAKDKLGTMTSSKSDLEAKE---------------------------------------GQIPNESNFVEFVSLLESINSIRFGGG---NEAEEEIE-----ERNEQSMMTEKDSDVSE----------------STGQHERPNPPNSLATDTMKTIPETLIPIVSPESPQTDKDRDPDYDSLP-SQTSQSESSMLQVICRPEATSKEEA-----YTFHTVHRERP---RKLYNER---ALNLPLGAELITGNICDLLSTSS--NSECQDGLAGGPSECPFQRRILPTRRLRPRRTHPEIFQEEDSLDDSSE----------------------------------------------------TSTQEKPSRKLYYKLKVFPG---KWVNILYDRLTLMALLDRNMDMTENMVAVFLAFLVAFLGFVLLNEGCFKDIWVFQFCLVIASCQYSLLKSVQPDAASPVHGHNQIVIYSRAAYFCIFCGLIWILE---IVLRTPDLPVSTFYGITIVTSDVLQYTQDILVGFTYCFPVTFLLGLFPQINTFVIYFLEQIDMHFFGGTAATGLPSAVYCIVRSLTALSLLYGFCLGALKEPWDEQHIPALFSGFCALLVVVSYHLSRQSSDPSVLFSLIKSKLMPSLGHGEEEEEESAE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NTDPLPEKLRGSVKEILLSDLVVCSLASVLTFAITASTVFLSLRPFVSIVLYAVAATVGFVTHYLIPQLRKHHPWLWISHPVLKSKEYSQFEPREDAHLMWFERLYVGLLTFEKYIVYPAIILSALTNDGFTLSHRKKLGIHCDVLLMTVAGMKLLRASFCDPSYQFLTLIFTIVFFEFDCSSASETFLLNFFLMSIIFNKLWDLLHKLHFILVYIAPWQIAWGSAFHAFAQPFAVP------------------------------HSAMLLLQTFITTLFYTPLSPFLGSAIFITSYPRPVKYWERNYNTKRIDNSNSRLVSQVDKETGCDDNNLNSIFYEYLTRSLQHSLCGDLMLGRWGNYCAGDCFILASDYLNALVHLIEVGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDDYCCCCEPGHLPHVLSCNAAFNLRWLAWEVTTTKYLLEGYSISENNAATMLQVYDLRKLLITYYLKSIIYYLVISPKLQMWIKDQTMQEALVFYTKWHHIEKDPAVFSMKIDEDYVHCLQGVTRASFCNVYLEWIQYCANKL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------EEP------VDSDEDSPLVTLCFALSVLGRRSLSTAAHNRSNSLESFLYGFNTLFKGDFRIA-AKDEWVFADMDLLQMVVAPAVRMSLKLHQDHFTSLEETEEPAVLHEAISSYRSSLVICHESDPAWRRAVLSSRDTLLTLRHMVDEGADEYKIIMLYKRHLSFKVIKLNKECVRGLWAGQQQELVFLRNRNPERGSIQNSKQALRNMINSSCDQPLGYPMFVSPLTTSYMGSHKQTRNIWGGPFSLDSIRLWLLSRWFRVRKD-NLTSCNSGMNMEDVDCAGSSMSQNHNSATSQSLSLYHGRPR---------SSQSRHHAA---------------------------------------------------------------------------------------------HREYRSRSVQPQ---AQRPPVTSRSGPILDSQHG---SASGG----------------PGLVQRLSNSQLSFNTSSIASVFSQVPRLSTTG----PLVSAAGPHRSGQVSSSSSTLSLLFGK-------------------------------------------------------------------------------------------------------------------------------------RSFSSGLVISGLSAADGGNTSDTQSSSSVNIALGPSCRSSRTTQQWTSEAYESI-------------------------------------------------DASS-----------TIGTG------PKVHSTDKSLDESTSAFHEAPEERTI--------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18490-1", "uniprot_id": "PCX_DROME", "id": "P18490-1", "name": "Protein pecanex", "aln": "MGSQTLEILRQGVWASLTGGYFYDPHQGVFCNVVHLYLWLYLLCSPFVAYLYFPSTWLTWCLYCVITSLTILMVKLANLALHRLYDRAQTMSEGNLKGQFVKVTKETEPRHDDEGGIEMKVIRPGGSRISGEQAINEASEENSIMSIDNVNSIIDLKVDVHRKNSSESIELMFYAPSMLSGGSQQDQQSLAGSASVSKSIRSTGPGGNSSTSAAAQADMFNKYLTVYPEVVEAAGSSAGSADGGSSGGDSRSGAAVSTLGHTGAGTAPAQHVRTGHLSRKCSEVFSRRHRRRLERQSSLDTAAAAANSNAENKLMRNQSDTIATAAPSFLHSQPTNKARGQTNPRQHFITSAPSTGIGGGDAPTSSTAVVVIAPASNSLVNPGRSSRLQRHRSSETHDERLKHQSRGGLFQPILQLPHHSAASSIGALAVLGGGGNVAANDVEDMELGLVRNAGSGGVADACSRALQSWILDPFPDGYLEDDSYTKSDLGIEQPHQPTFRTQHRHHHHHHHLHHHLGGAIIRKDPTSTMSALQLAAVTQPGTGGSVTGGGGAAGGGGSAAGMKRRRHSNATSYKHGSSQSNKSSLVGGGGSRGPSGEAGTSGGAGGTGGVRRIKSAALEVLCPQPSVSNLSPHPNSVEAISGQQQMRNPLPPPSKSLVRNQHLNLYPTQGYGDGTPSAGGGGPGNSSTCSSLFFGSSSACGSTTALIEPPVYPIVEHSDEKTAHEEHGDDCLGIGQGNADDDDEVDDVPIRRRTRALGCSQTHYSVESDVGGFLADEVGADEDVFKDFDDNLEHILSELQQTHNQLDDVLKTHDLHHHSHLHHHKAASVEGAGPSGGSVAVGVSAGNDDEDEETEDNNTGSRSPLLNDRNRQPATLREIQADKQLRQELSHQSGAVIPAPNPPVPIRSEADSGCPSSDCEQVSASSKDQLLSGIELELQQYQILQRCQLDEEQPCTSKMAAKSLGAIPKVVKYREVDELRRRRRGGSPADAAEAGNEFALVKQTKQASRNSSSSNSTHSISLTDSLTADIHKMLWLMHGGAVDDRGRPITGTSADGTPIPASSSLVPPNMSNAHFQFYQDAIQALQGTHPTSGSSVEHMTNIELARDKLRLDAKLMCEQLVAAAEANSGVRGNTLATQQMTQQQVGMLMRGGSSSRHPSSAPFSVQGLINVIRSERPAARSQLDALQQLSDAAAALAANASEAASVSASGAGGGASSGGGGVLSALGLANHPSNQISQISQLSQMSQPMLNVDGHFAPYCDYWRPACLLSATEKPAAPKSFYKYRFKWCGQEHEFKIAMDRLELLALFDRDLHWMHVLLASLLCTLVACLGAAILQHDHYKDLCALLFCAVIAGAQYSLVKSVQPDAASPVHGFNKTVAYSRAIYFCLAGGMLLLLKRLDTDYGERTPDPVVFFGMRYSPADVVALLLQALYILLLCFPIIFSVGLCPQINTFLMYLLEQIDMHVFGGNAASSLLGSFLCVVRSVLAVMLLYGPLYGALDEQRGTQYI--LFSIFCAMLVPLGYHLSRCASDFSHLWRLIKTCIVSTYRDDEDEDLSQMQHIATGTVTGSGTANSTALQLTTSTPKQHRQTDVKTEHEQIELSSLEKLTVNEEHHEKDHGADDQLETDQDLPLQQKHSKSKTSSLGSSQQTLGKTISSSKRAITASSSCTSIGTGEPAVEAGALTEEAVEGEEQRRNTLAGEVGSKHELAENYDQAAKIDECEDKISSSSATNPGDMSTLTAGAGTATTDATPACLEADPDAEAEAPADEKQHQGILGTGTGTGTGTTEASENGSGGGANGNTNSNGTGNDLPDPLPRKLQATVTTRLKNDLVVMTLLAVSVLGLHCSTVFTALQPDLNVVLYSFIGVLGLLLHYIVPQMRKHMPWLCFSRPLLRQREFGQFEVLNAPKIMWFEKLYIYLSVLERNVLFPLLAISSLTADSQLIVAK--FGLPWGTLIVAICALKFVRNAYSDPTNQYLIIIFTVLLFRIDFAMATETFIIDYFFVSLAFRKCCDFLLKLQFIVTYIAPWQITWGSAFHAFAQPFSVP------------------------------HSAMLFLQAAISAVLSTPLNPFLGSAIFLTSYVRPIKFWERDYNTRRIDHSNTRLSSQLERDLGADDNNLNSIFYEHLTRSLQHSLCGDLLMGRWGNVNQGDCFVLASDDLNCLVHIIELGNGLCTFQMRGLEFRGTYCQQREVEAITEDVEDNDGCCCCDPGHLPQLLSANAMFSTRWLAWQVVAAQYVIEGYSISDNLASATLQVFEYRKVLITYYIKSIIYYVVKNPKLEQWLASGPIQDALQHTLSRQFVDLD-PIFNFNLDEDFDFRAVGITRSSFCYVYLKWINYCVDMRRDANSMGGAPPAQAPAAAGGASSAPATAGVAPPAPVTPAHNDSKSTPNLSAHGGQAGPSSGQSKSQSQQQLRRPQKSVAQETSVGGGGVVVGGTTVPGTGGVTGGGGDPQLSSSHSFANISRQTSESAPGLGGYVAYMDQNVFVKLAKSSTTTGAGAGAPTSRKESQEKPALRLKLASVGKDAPLVSLCLALGLLARRSLATASHSALTGVEFFLHGLHALFKGDFRITSPRDEWVFADMELLHSVVAPAVKMALKLQQDHITNPDEFLDPHALYDAIDNCSNELVISHEADPVWRSAVLRGAPNLLALRHVMEDGSDEYRIIRLTKRCLSFRVIKLNRECVRGLWAGQQQELIYLRNRNPERGSIQNAKQALRNIINSSCDQPIGYPIYVSPLTTSYADTNAQLCEVIGGAITLDTIRHTVLGWWHRIRERCRQGCSSGS-ALEPHPGSGPVQLGACNFGSGGSVVGAASTATGVGASTGSGLGVAAPGTAGSTGGESGDLAPVFISAPLYNTLTVNSYYSVRPGNVPGGPIPGNLGGNYVSDSLAVVRGGLAVMPVKPTSTTLIAGLLNRERDETSGSGIMGAGASGPTRATSSGGVRSRRPEVGSSRGRDHERRATLPIASGGAGGEPGKDLTAPQTQVEHEPSPRSTKLSSSSGSLGLGMGVGLGNIITTPGDYPRKTKGPICLTAVDTGTSSSAAEGKPAGSGTVAGTGVGGVIRKPRIEIFKKVIIVDDTGIYDCLDIIDAVVWPTERMRNNGGRLSWKDWEPSAGMVGHVVHCWTPNHKDIRFRSHVNRYVYLVEIGDHYVPVEELGLREYNQIMGSTEEMANSRRSSIQRDFHEYNIQLKLAGLAPIIGGGESSTATTSDASKSHKAKIRAVSSSSSEDEDTSSTRSIPLPQGDDGDLTNFTRLVSMWKEIILDNNKRRLYDMGELSPELLQKLDDAVQQQQQLEDALAEESKEKGTATVTANEGEEGVGEMEIEPEQEQKEVVYLEEQSPLEEVTVSKPDEQPAQPTIPASPVPAETSSTSSAKSTSSPSLCQEEEDAVDPEETPELASEESPSDENGESEAGTTV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **.:: *******:****:::**.:. * * *****::** *: :* :*.. :** .:: : ::*: . ** ::*:.: : . . : : : .: . : : :: . :.. : . * : . :: : : : . . . : : :. : . . : . . .. . .. :. . . ..: . : . . . : :.: :. .. :: . . . ...: . . * . . . . :. . . . . .. * . : . : .: : : : : ** :** .: .:*..: : . * :*: :: *. .* . . : . . . . . . . : . * : * :: *. : :. : . : : : . . .* .. : :. . .:*: .. . .. . :* :::: : :** . : .:: *** *:**:** . . ::* :* **: ** *... :*: .: ** *:*..****:******.***:**.*: : ***. ***: .:: :*. ..:*: .. : : * : *** :** ****** *:****** .***.*.:.: .:. .: **: * **: .*:.* . *:* *** **.:** :.***** :** * * :*: :... . : : .****.::: :*. * **:: : :* :.: .**** :*:* :.:**::. ..:*:: *:::**:*** **: :*:*:*:.:*: * * : .::****:**: * :*: :::* : :.::* *. : :* . ::: ..:*::* ::.:* *: : **:::*.:* :*:*::::*::*: * * *:* **:*::.*:****::***:**.*** *::* . * : :::: ***.*****.**:*** **:*:**:.***:*:*:**:** *:::: * **..*******:***:**.****** :***** ****:**** **.:**:**:**** ***:****************** *. *:: ****.*****::**.** * ***:*::. ::*::***** :* *:: *:*:: *::** **:******:* .*** *: . .: .:* . :.:: * .:*.:::*:*: *:**:*:* *:*:**::*. :: .:*:.**:*.:** *.**:*.**:*. .:: **:*::.*******:: .:********:**: **.**::*:***:**::* :* :* *::** . ..:**.**.**.** *:* . **:***::::*::**::* * : ***:***:*:**************::************* **.***:********:***::******** .:: * .: **..:*: :* . * *:*: ... :* . . .. * . :. . :::... ::* * * : : :: . * : * : . : *.* . . :*:*:: . *. :.:. * ::**:. **. *.* ::*... .. *: .:. .. *: . . . . . : . ", "identical_positions": 537, "similar_positions": 607, "identity": "15.57%" }, { "cls_id": "homologset.agr.MGI:2445015", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6WAY2-1", "uniprot_id": "PLPR1_RAT", "id": "Q6WAY2-1", "name": "Phospholipid phosphatase-related protein type 1", "aln": "MAVENNTQRSYSIIPCFIFVELVIMAGTVLLAYYFECTDTFQVHIQGFFCQDGDLMKPYPGTEEESFISPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIAEEKMILTGDCCYLSPLLRRIVRFIGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCQPNYTSTDCRAHHQFINNGNICTGDLEVIEKARRSFPSKHAALSIYSALYATMYITSTIKTKSSRLAKPVLCLGDLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMCVVHNFKGTQGSASKPKPEDPRGVPLMAFPRIESPLETLSAQNHSASMTEVT---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFZ2-1", "uniprot_id": "PLPR1_MOUSE", "id": "Q8BFZ2-1", "name": "Phospholipid phosphatase-related protein type 1", "aln": "MAVENNTQRSYSIIPCFIFVELVIMAGTVLLAYYFECTDTFQVHIQGFFCQDGDLMKPYPGTEEESFISPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIAEEKMILTGDCCYLSPLLRRIIRFIGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCQPNYTSTDCRAHQQFINNGNICTGDLEVIEKARRSFPSKHAALSIYSALYATMYITSTIKTKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMCVVHNFRGTQGSPSKPKPEDPRGVPLMAFPRIESPLETLSAQNHSASMTEVT---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBJ4-1", "uniprot_id": "PLPR1_HUMAN", "id": "Q8TBJ4-1", "name": "Phospholipid phosphatase-related protein type 1", "aln": "MAVGNNTQRSYSIIPCFIFVELVIMAGTVLLAYYFECTDTFQVHIQGFFCQDGDLMKPYPGTEEESFITPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIAQEKTILTGECCYLNPLLRRIIRFTGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCKPNYTSADCQAHHQFINNGNICTGDLEVIEKARRSFPSKHAALSIYSALYATMYITSTIKTKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMCVVHNFKGTQGSPSKPKPEDPRGVPLMAFPRIESPLETLSAQNHSASMTEVT---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQH6-1", "uniprot_id": "PLPR1_DANRE", "id": "Q6IQH6-1", "name": "Phospholipid phosphatase-related protein type 1", "aln": "MASDN-THRSYSIIPCFIFVELVIMAGTVLLAYYFECTDTFGIHIQGFFCNDADLLKPYPGPEESSFIQPLILYCVVAAAPTAIIFVGEISMYIMKSTGEALLAQEKTIVTGECCYLNPLIRRIIRFIGVFAFGLFATDIFVNAGQVVTGNLAPYFLNVCKPNYTGLDCHFSHQFIANGNICTGNQVVVERARRSFPSKDASLSVYSAVYVTMYITSTIKTKSSRLAKPVLCLGLLCAAFLTGLNRVSEYRNHCSDVVAGFILGSSIALFLGICVVNNFKGTHSTPTKQKQEDYRGLPLMTFPRVESPLETLSAQGKSCQATLLTSSQPNTWSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * *:********************************* :*******:*.**:*****.**.*** **:****:**:******:******::*** *:*:*:** *:**:****.**:***:** **********************:*:****.**:****. **: :*** *******: *:*:********.*:**:***:*.*********************** **:*******************:******:::*****:***:**:**:.:.:* * ** **:***:***:**********.:*.. * :* ", "identical_positions": 248, "similar_positions": 57, "identity": "74.25%" }, { "cls_id": "homologset.agr.MGI:2445019", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PF93-1", "uniprot_id": "PK3C3_MOUSE", "id": "Q6PF93-1", "name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "aln": "-MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAE--GKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGSAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTRTPGRT---------SSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKE-YGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNATTRDQLNIIVS-YPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYEN--------------FDDIKNGLEPTKK-DSQTSAS-ESLSNSGVSSGDIDSSQIITNPLPPVASPPPASKAKEVSDGE----------------------------------------NLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQD-TQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNE--KMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGG-KYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSETGPYGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88763-1", "uniprot_id": "PK3C3_RAT", "id": "O88763-1", "name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "aln": "-MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAE--GKPLALPVRTSYKPFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGRAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTRTPGRT---------SSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKE-YGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNATTRDQLNIIVS-YPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYEN--------------FDDIKNGLEPTKK-DSQASVS-ESLSSSGVSSADIDSSQIITNPLPPVASPPPASKSKEVSDGE----------------------------------------NLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQD-TQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNE--KMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGG-KYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSETGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NEB9-1", "uniprot_id": "PK3C3_HUMAN", "id": "Q8NEB9-1", "name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "aln": "-MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAE--GKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRT---------SSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKE-YGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIVS-YPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYEN--------------FDDIKNGLEPTKK-DSQSSVS-ENVSNSGINSAEIDSSQIITSPLPSVSSPPPASKTKEVPDGE----------------------------------------NLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQD-TQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNE--KMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGG-KYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q9F3-1", "uniprot_id": "F1Q9F3_DANRE", "id": "F1Q9F3-1", "name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "aln": "--MDTDKFNYVYSCDLDINVQLKIGSLEGKREQKSYKALLEDPMLRFSGLYQESCSDLYVTCQVFAE--GKPLALPVRTSYKAFSTRWNWNEWLRLPVKYPDLPQSAQVTLTVWDVYGPGRATPVGGTTVTLFGKYGMFRQGMHDLKVWPGVEGDGTEPTSTPGRT---------SSSLAEDQMGRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFPRVKSGERE-YSIVYYEKDADESSPLPTSSDIVKVPDPQMCMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIVS-YPPTKQLSSEEQDLVWKFRYYLTTQEKALTKFLKCVNWDLPQEAKQALELLGKWRPMDVEDSLELLSSQFTNPTVRRYAVARLQQADDEDLLMYLLQLVQALKYEN--------------FNDIQGGLEPANKRDNQGGLT-ESS-----TTGDLDSSQLAS----AIAVMPSSQKGKEGTDGE----------------------------------------NLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQD-TQQRDPKTHDMYLNVMRRFSQALLKGDKSVRVMRSLLASQQTFVDRLVQLMKAVQRESGNRKKKTERLQSLLADNE--KVNLSEIEPIPLPLEPQIRIKGIIPETATLFKSALMPAKLIFKTEDGE-QYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFVQSVPVAEVLATEGNIQSFFRKYAPNDKGPYGISSEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLSKEMVEGMGGMQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVGALFAAVVEQIHKFAQYWRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1M7-1", "uniprot_id": "Q9W1M7_DROME", "id": "Q9W1M7-1", "name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "aln": "MDQPDDHFRYIHSSSLHERVQIKVGTLEGKKRQPDYEKLLEDPILRFSGLYSEEHPSFQVRLQVFNQ--GRPYCLPVTSSYKAFGKRWSWNEWVTLPLQFSDLPRSAMLVLTILDCSGAGQTTVIGGTSISMFGKDGMFRQGMYDLRVWLGVEGDGNFPSRTPGKG---------KES-SKSQMQRLGKLAKKHRNGQVQKVDWLDRLTFREIEVINEREKRMSDYMFLMIEFPAIVVDDMYNYAVVYFEPEGDVKYKLPAKPKLVSVPDSEIQMENLVERKHHRLARSERSGISDRDAKPTASIRDQLHTIVYRYPPTYVLSSEEQDLVWKFRFYLSSHKKALTKFLKCINWKLEDEVTQALWMLANWAPMDVEDALELLSPTFTHPQVRKYAVSRLAQAPDEDLLLYLLQLVQALKYEDPRHIVHLHGCIFPERDVVRSILDDNGSLLDQSSLSDLSATSSGLHGSVIPANQRAASVLAAIKSDKSVSPGSAGGSGSGGQGSVALPNPSAPATPGSSSLPCDSNSNALMLAEGISFGSVPANLCTFLIQRACTNATLANYFYWYLSIEVEEVESVRKQDERAHDMYAMVLKMFLKVLENGNFNLRGIFYNLRKQRRFIDELVKLVKLVAKEPGNRNKKTEKFQKLLAEQDMFKVNFTNFEPIPFPLDPEIYITKIVPMRTSLFKSALMPAKLTFVTSIAHHEYAAIFKHGDDLRQDQLILQMITLMDKLLRRENLDLKLTPYKVLATSSKHGFLQYVDSCTVAEVLAREGNIHNFFRKHHPCDNGPYGISAEVMDTYIKSCAGYCVITYLLGVGDRHLDNLLLTTNGKLFHIDFGYILGRDPKPMPPPMKLSKEMVEAMGGISSEHHHEFRKQCYTAYLHLRRHANVMLNLFSLMVDATVPDIALEPDKAVKKVEENLQLGLTDEEAVQHLQSLLDVSITAVMPALVEQIHRFTQYWRK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22543-1", "uniprot_id": "VPS34_YEAST", "id": "P22543-1", "name": "Phosphatidylinositol 3-kinase VPS34", "aln": "--MSLNNITFCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELMLIGSNVFPSSDLIVSLQVFDKERNRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLTFSSHLRIILWEYNGSKQIPFFNLETSIFNLKDCTLKRGFESLKFRYDVIDHCEVVTDNKDQENLNKYFQGEFTRLPWLDEITISKLRKQRENRTWPQGTFVLNLEFPMLELPVVFIEREIMNTQMNIPTLKNNPGLSTDLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKYRRLERASKNANLDKQVKPDIKKRDYLNKIIN-YPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFEN-----------------LSTFSDKSNS--EFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVIS-------------------------------------------PLAEFLIRRALVNPRLGSFFYWYLKSESEDKP-----------YLDQILSSFWSRLDKKS------RNILNDQVRLINVLRECCETIKRLKDTTAKKMELLVHLLETKVR---PLVKVRPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFKTTLNQ-PYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVNALLPIVIDHLHNLAQYWRT", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: : * .*. :::*: :***:: . . : :* * : * ..: * *** : .: **: :.* .* . .*: *: **:: :*. .: : : : : *. .. : : * :::*: .*:. .* . : . .: . : :.** * :.: : :: .* * :*: :* : : . : . :.. *.: :: :* *:::* *: :.. *:: ** ** *: *: *** *: .*:. :**:*:** .::*****:*:. * .* :.* :: .* :*::*:****.. :.: ** *** ** :* *::* :******:*: :*: : : . . . : :.: .: . . *. *** ** *. *..::***: * *: :: * . * : . * * ::: * . : : : .. ** * : ** : : ... *.:**:*:: * : * :.:***:* * :: * * * :** *********::*:*:**::**:.**:********:***..:.* :::: . .:*.:* .* .::: : * :... *:.. *:*.::***********:************:* *::** *******:****:** *** :::*.:** .*.::.:**. *:.*: *** :.::****.** :.:*** ::*: :: :*.:.:.*.:::*:*. ::*.*:: *: *::. :::::*.::**** ", "identical_positions": 242, "similar_positions": 291, "identity": "25.18%" }, { "cls_id": "homologset.agr.MGI:2445020", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R3S6-1", "uniprot_id": "EXOC1_MOUSE", "id": "Q8R3S6-1", "name": "Exocyst complex component 1", "aln": "-----------------------------------------------------MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVT---------------------------------------------TERPVQVKVVKVKKS-DKGD-FYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKVYKWVASSTAEKNAFISCIWKLNQRYLR-KKIDFVNVSSQLLEES-----------------------------------------------------------------------------------------VPSGENQSVAGGDEEAVDEYQELNAREEQDIEIMMEGCECAISN--------------AEAFAEKLSRELQVLDGANIQSIMASEKQVNTLMQLLDEALTEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVK-----LLSEIEFLVNHMDLAKGHIK---------------------------ALQEGDLVSSRGIEACTN-------------------------------------------------AADALLQCMNVALRPGHDMLLAVKQQQQRFSDLREHFARRLASHLNN--------VFVQQ-----------------------GHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDY-----------------------------------------------GKYEGLTKNYMDYLS-------------------RLYEREIKDFFEVAKMKMTGTSKESK-KFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGSRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPL------------------------------CLAEQDFISKFFKLQQHQNMSASMTEAEDLDGGS-LLRQHSSGTLLPVSS----------EKDMIRQMMIKIFRCIEPELNNLIALGDKVDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKNAER-----------------------------RGDLDKAYTKLIRGVFINVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNHFFEGVEARVAQG--IREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEEN------LLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZLJ5-1", "uniprot_id": "A0A8I5ZLJ5_RAT", "id": "A0A8I5ZLJ5-1", "name": "Exocyst complex component 1", "aln": "-----------------------------------------------------MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVT---------------------------------------------TERPVQVKVVKVKKS-DKGD-FYKRQIAWALRDLAVVDAKDAIKESPEFDLHFDKVYRWVASSIAEKNAFISCTWKLNQRYLR-KKIDFLNVSSQLLEELPK----------------------------------------------------------------------------------VAEESVPSGENQSVAGGDEEAVDEYQELNAREEQDIEIMMEGCECAISN--------------AEAFAEKLSRELQVLDGANIQSIMASEKQVNILMQLLDEALQEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVK-----LLSEIEFLVNHMDLAKGHVK---------------------------ALQDGDLASSRGIEACTN-------------------------------------------------AADALLQCMNVALRPGHDMLLAIRQQQQRFSELREHFARRLASHLNN--------VFVQQF-----TQALLQLYSRSYFLSVPGHDQSSTLAQHSAELTLPNHHPFHRDLLRYAKLMEWLKSTDY-----------------------------------------------GKYEGLTKNYMDYLS-------------------RLYEREIKDFFEVAKMKMTGTTKESK-KFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGSRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPL------------------------------CLAEQDFISKFFKLQQHQNLSASMAEAEDLDGGS-LSRPQSSGSLLPVSS----------EKDMIRQMMIKIFRCIEPELNNLIALGDKVDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKSAER-----------------------------RGDLDKAYTKLIRGVFINVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNHFFEGVEARVAQG--IREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEEN------LLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NV70-1", "uniprot_id": "EXOC1_HUMAN", "id": "Q9NV70-1", "name": "Exocyst complex component 1", "aln": "-----------------------------------------------------MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVT---------------------------------------------TERPVQVKVVKVKKS-DKGD-FYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQRYLR-KKIDFVNVSSQLLEES-----------------------------------------------------------------------------------------VPSGENQSVTGGDEEVVDEYQELNAREEQDIEIMMEGCEYAISN--------------AEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIELKLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVK-----LLSEIEFLVNHMDLAKGHIK---------------------------ALQEGDLASSRGIEACTN-------------------------------------------------AADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNN--------VFVQQ-----------------------GHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDY-----------------------------------------------GKYEGLTKNYMDYLS-------------------RLYEREIKDFFEVAKIKMTGTTKESK-KFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPL------------------------------CLAEQDFISKFFKLQQHQSMPGTMAEAEDLDGGT-LSRQHNCGTPLPVSS----------EKDMIRQMMIKIFRCIEPELNNLIALGDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQIRQMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKNAER-----------------------------RGDLDKAYTKLIRGVFVNVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQPLEKLNHFFEGVEARVAQG--IREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEEN------LLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQSH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P2G2-1", "uniprot_id": "A0A8M9P2G2_DANRE", "id": "A0A8M9P2G2-1", "name": "Exocyst complex component 1", "aln": "-----------------------------------------------------MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVT---------------------------------------------TERPVQVKVVKVKKS-DKGD-FYKRQMAWELRDLTEVDAKDANKENPEFDLHFEKVYRWVASSTAEKNSFISCIWKLNQRYLR-KKVEFVNVSPQLLEELP-----------------------------------------------------------------------------------KAEESVPSGESQSVAGGDEDALDDYQELNAREEQDIEGMMEVCEYAISN--------------AEAFAEKLSRELQVLDGANIQSIMASEKQVNTLMQLLDQALAEVDTIEGKLLSYEEMLQSVKEQMDQISQSNRLIQISNTNNGK-----LLDEIQFLVNYMDLSKGHIK---------------------------ALQEGDLSSPKGIEACIN-------------------------------------------------ASEALSQCMNVALKPGHDKLMAIKQQQHLFSELRDTFARRLTNHLNN--------VFVHQFNHFSHFKMTIPQFYRSSCLSLPGHDQSSTLAQHTAELTLPKHSPLHRDLLRYAKLMEWLKNTQR-----------------------------------------------EKYEGLSRTYMDYMT-------------------RLYEREIKDFFEVAKIKMAGTSKDGKGKFATLPRKESALKQETESLHGSSGKLTGSTSSLNKLAVSSSNSRRSQSSSLLDMGNMSASDLDVADRTRFDKIFEQVLSELEPL------------------------------CLAEQDFISKFFKLQQIP----TLAQGENMDDSDGLMHSKPVSEHRHSIS----------EKDMVRMMMNKIFQSIETELNSLIALGDKIDSFNSLYMLVKMSHHVWTAENVDPASYLSTTLGNVLVTVKRNFDKCISAQIRQMEEVKISKKSKVGILPFVTGFEEFAKLAEAIFRNAER-----------------------------RGDLDKAYIKLMRAVFNNVEKVANESQKTPRDVVMMENFHHIFSTLSSLKISCLEAERKEAKQKYTEHLQSYVINSLGQPLEKLNHFFEGVEARVAQG--VREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYRKVDKHLCDEES------LLQVVWHSMQDEFIRQYKHFEGLINRCYPGSGITMEFTIQDMLEYFSSIAQSH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVG4-1", "uniprot_id": "EXOC1_DROME", "id": "Q9VVG4-1", "name": "Exocyst complex component 1", "aln": "-----------------------------------------------MLSIGAMANIKHTLQKELFLASGERLLSVVTVVKK-KDKKPCYLCVVTT---------------------------------------------APPVPVVTLCLIKQS-EQREGEYKRKRSWQLDEIKWVDGRNEQFETHEFDLQLEKLYKWYALNPHERQNFLAVLNRQIQKSVRGQRAEFRNVPAAWLSEKSPEKV-------------------------------------------------------------------------------ALGRAVQKTQHMDDEEDEEEEAQEFTALTDKEANELGKLFSECDFAIKD--------------AEQFIEQLSRELHDLDGANMQSVLASEQKVLKMMEHIDNAISEADKFENRLDSYEDILGHVKETMEKIGGKNAMIEIANNNNIK-----LMKELNKVISQLDLPHSQQQ---------------------------ALDEPDLKTANGRKAAIA-------------------------------------------------AAQCLQQAMNSDIDPALLRLEAVQDQRKRFEKWKQKFSATVSRFMNN--------LFIHLG------------------------NEIGDMQVTSTELTLPNHSNVHRELTPYTELMHWTKAMDR-----------------------------------------------KTYDGLMRVYTASLS-------------------KIYDRDVRNFFNLAKIQVTEKLRNSR---------------EDLDMSTSSRKSAVSTIPYGTLGIN-----RDQWG----------PGVETADRMRFDALLEKVLAELEPI------------------------------ALQEQLFCINFFQMDVISPTTKNTQTTLEMEKAVDMTQSIISGAVSPSGDGVPQKRIDRQINEDVRKLMMGLFGCLEPELVSFIQSFERVDSFYSLYVFVRLTQHVMSAQ--DTHSFLSMTFASALVQVKRSFDRFMQNQLLSIREAKLHKRSKA-ILPYVENFENFAQTAEGIFRKSDR-----------------------------RTDMEKWYLQLVNAIFEGIQLHSQEHPKTPVQVVRMENYHHMYALLAQLKVPGLDALKKEAKKCYNDALKAYVTQYFGRPLEKLNQFFEGVQLKVAQG--VKETEISYQMAFSKQELRKVIAQYPAREVKKGLENLYKKVEKHLSEEEN------LLQVVWHAMQEEFIAQYNYLEERIQKCYAGAMINLEFNIQDILAFFSDIARSH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33332-1", "uniprot_id": "SEC3_YEAST", "id": "P33332-1", "name": "Exocyst complex component SEC3", "aln": "MRSSKSPFKRKSHSRETSHDENTSFFHKRTISGSSAHHSRNVSQGAVPSSAPPVSGGNYSHKRNVSRASNSSQTSNFLAEQYERDRKAIINCCFSRPDHKTGEPPNNYITHVRIIEDSKFPSSRPPPDSKLENKKKRLLILSAKPNNAKLIQIHKARENSDGSFQIGRTWQLTELVRVEKDLEISEG--FILTMSKKYYWETNSAKERTVFIKSLITLYIQTFEGHVPELVNWDLSLFYLDERSYQRAVITNRPGSVSPIKSPTSNFTTNTTQSVGSVPFSAPTERTRRSETESVNPVSTPASVEYHAGMKSLNKAPYSSNSTLNEVNKRYELEQQQQQEEAELRRLEEQKRLQLQKENEMKRLEEERRIKQEERKRQMELEHQRQLEEEERKRQMELEAKKQMELKRQRQFEEEQRLKKERELLEIQRKQREQETAERLKKEEQEALAKKEEEEKSKRNKVDNESYTQEINGKVDNLLEDLNAVLAEETETTPTMQNGTYVPERSTARAHDQLKKPLNIAKVESLGGSDLNDSISLSDEIAGLNTSNLSGEDQDEKNDLSFEKGDEVRYSNNFEGEAPHVYHEVSIIQEEAPAVSQKLILPEENNESEALIESKEEIKTMENIDDEVLLEILTDINWSIEDDADSMIERIDLRLAETEYLFNQNLLSLQKIGPNIRPYEDKVNDECHRIIPTLSLFLMEMSNFSNDIENVESQDNGLQVESANKKLLWNTLDELLKTVSLDEISLNQLLECPIREKNLPWMENQLNLLLKAFQAIGSDGNEVEYNLREISGLKQRLQFYEKVTKIFLNRIVEEMQKKFSNIRGQDISHDQMIRILTTLLIFSPLILFCKEISQKSYQAIVENWNVSIQPVYMELWTKKISQLQGIDTNDEKMNELSLSQLLNEWDTFRKERKTNDINPVFKNSFSLLTECLQTMRQECIVYQNFVEVFFHISSKHNFEEYIKHFNDPDAPPILLDTVKVMQSDREAA------------VIETQLVSRIFQPIVTRLSSYFVELVKAEPTVAPALTFYLENEIKSLES-SNHEFLLSAVTRMYTQIKQVWSDNVEEQVLHFERISN-ATTNGEILPGILDLPVGLKNSEDLFQFAKRSMDIKDTDEGYESIELMNSSFRKLSIAATRSITHKEVNSSINPNLSDTAALNNDYMETISLLVNSNWLTEMLSMLNFNKDGIFDTSLQNVKKVFDVEKESYASFLLRDTMPKLTAFVYGVSNIIENTNNVNMTNPSRWAAYSRQNLENILLAYTSHEIETLVKRLHTHMVNDFGYHQENAINNVLCDKLWSCIQGQTVSLYLKLYTVIDKHYRG--TNIRFTKNDIISAFEEYKNA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ::: :::: .... * . . : :.:* * : ..: :::: :: : :: :* * :: *: * * * :.* * * : . *: *: : .. : :: * : : . : :: * :: ::: : . .: * .::. * : : * : .*::: : :: : : . . *: .*: :: . * : . : .:: : *:.::: :: . : :* ** . . . *. : : * ::: : :.. : . : :* :: : . :*. . :: ::: :. : : : * : : : ::*:: : *:: :: . : : * . : . : .::. *. : :.::* * :.: .: * * **::. : : : :: :* : ..* . : : :. : : . : :.: : : . .:* :. . :*: :. :. *: :.. . :: *** : : :* :*: :.* * .* . :. : . :: :* :* : .: : * * ::: ::.*: : ::*. : .: **. *. **. : : :. : * *:.:*:*.::: *..:*::. :..*: :: :.: .:. * : :* .:* : : * : * : * * .:.*. :*:: .. .: ", "identical_positions": 82, "similar_positions": 305, "identity": "6.05%" }, { "cls_id": "homologset.agr.MGI:2445022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C9S4-1", "uniprot_id": "CC186_MOUSE", "id": "Q8C9S4-1", "name": "Coiled-coil domain-containing protein 186", "aln": "-------MKIRSRFEEMQSELVPVSMSETEHIASISSDATTEKTSELRDDSCISVSGDESSRLETGAELLSLDSDRILCQ-TNEHC---------SQIEVQESHIPDCGSGENSCANTDTCPEDS--GQIDDFPGGDFTEQVS-----KTKEPEQTVTQILAELKSSAPAEAAN---------PKTASASLYDTDCTRKLISEMKTVSASDDLLGEIESELLS--AEFAEGHQVPNGLNKGEQALALFEKCVHSRYLQQELTVKQLIKENKNHQELILNICSEKDSLREELRKRTETEKQHMNTIKQLELRIEELNKEIKASKDQLVAQDVTAKNAIQQIHKEMAQRMDQANKKCEEARQEKEAMVMKYVRGEKEALDLRKEKETLERKLRDASKELEKNTNKIKQLSQEKGRLQQLYESKEGETTRLIREIEKLKEEMNSQVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEAEQIRQNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKAKCLEDERLRTEDELSKYREIINRQKSEIQNLLDKVKITDQLHEQLQSGKQEIEHLKEEMESLNSLINDLQKDIEGSRKRESELLLFTEKLTSKNAQLQSESSALQSQVDNLSCTESQLQSQCQQMGQANRNLESKLLKEEELRKEEVQTLQAELSAAQTEVKALSTQVEELKDELVTQRRKHASNVKDLSKQLQQARRKLEQTEN-----GNHDKDIS---------SMGSRSSSSGSLNAR-ISAEDRSPENTSSS--VAVDNFP-------EVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYVLREE-SGTLSSEASDFNKVHLSRRG-GIMASLYTSHPADSG-----LTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHQHELEQRTKKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3E2-1", "uniprot_id": "CC186_HUMAN", "id": "Q7Z3E2-1", "name": "Coiled-coil domain-containing protein 186", "aln": "-------------------------MSETDHIASTSSDKNVGKTPELKEDSCNLFSGNESSKLENESKLLSLNTDKTLCQ-PNEHN---------NRIEAQENYIPDHGGGEDSCAKTDTGSENS--EQIANFPSGNFAKHIS-----KTNETEQKVTQILVELRSSTFPESAN---------EKTYSESPYDTDCTKKFISKIKSVSASEDLLEEIESELLS--TEFAE-HRVPNGMNKGEHALVLFEKCVQDKYLQQEHIIKKLIKENKKHQELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQVES-----GSYDKEVS---------SMGSRSSSSGSLNAR-SSAEDRSPENTGSS--VAVDNFP-------QVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYILREE-SGTLSSEASDFNKVHLSRRG-GIMASLYTSHPADNG-----LTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHQHELEQRTKKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6Y8-1", "uniprot_id": "A0ACD6B6Y8_DANRE", "id": "A0ACD6B6Y8-1", "name": "", "aln": "MEPLDSQSELSPASDPSPSPEVSTGLEESTDVLSNGSDPVLQEQEEETEPDSLELDASLSGSVDKETQRQDTDMEVQEDEGAGEHAPADVNISCDSGTASIEDSRTQDNAGESLPAVLDGQLECSGIEETTDALPQSFSSVLNGTDELKTANGQTELTRTHMTPTSSSHAEELPDVVSVLQNSQTNANLNPYDTECSRKLLSEIERSLSQESLLDELEDELLNSQSEGVRKGSHPNGLQKDQNSMVLFEKCVQYKYSQQEKAIKGLLEENKKHQELILGICSEKDNMRDELKKRMETEKQHLYTIKKFESRVEELTKELKDSRDKLVHQDQAAKNAIQQMQREMAYRLEQANKKCEEARQEKETMVMKYVRGEKEALDLRREKEQLEKKLREATAEVDKQARRGNTLAQEKGRLQQLYDAKENEVTRLMRELEKVKEEINSHVIKVKWAQNKLKSETDSHKETKDRLKETTAKLTQAKEETEQIRKNCQDMIRTYQESEEIKSNELDAKLRETKGELEKQKQEQTDQLEMHKAKIKELEDLKRTFKEGMDELTTLRTKVKCLEDERPRWEDELCKYREIINRQKAEIQNQREKLTAITRLEEQHQRDEQEIASLQEEVENLNSQITDLQRDIEGSRTREAELLGFTEKLSSKNAQLQSESNSLQAQLDRLNSSSRELHNKLEDTERCLSDMTDRLKTEEQQRQEEVLALQTERTSLQTETSQLKTRVEELRDELVTQKRKQAVNIKDLTKQLLQARKKLEQVEN-----GGCDREGS---------SMGSRSSSSGSLNARGSSMDDRSPENQSGSSVVVVDSFP-------EVDKAVLVERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYVLREE-SGALSSEASDFNKAHLSRRG-GIMASLYTSHPADSG-----LTLDLSLEINRKLQAVLEDTLLKNITLKENLQTLGSEIERLIKQQRLPDDTAGRK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV40-1", "uniprot_id": "Q9VV40_DROME", "id": "Q9VV40-1", "name": "", "aln": "-------------------------MESAQATPPAEMENPASVENGDSGRDSNHIEGKAIGDVDMKADSIEQQLE--------------------------ESDVKTESNGDQLTDQDEG--------------------------------------KIEQDLKAAVLEQVP-------------------------------------------IEEEGLS----------------------------LRFKDLQAQEKVKELQQTPS--------------------QPPQNDILSHVHCLAQLEEQRRNYEQQLEQLRTSNVQKDNMIT-LIQRENAILGKEKQACRKEMEMANKEKEATVIKFAMKEKLLIDAKKEKEAVEKQLAEAKKEVKNVSTRFLAVSEEKSRMTYIIDEKCNEVRKYQRECEKYKTEMGHLESKLKYHINKLNIETEAKAVVERKLEE-------EKNAPNKLEEKANEKLKMEFEANTILLK-----------------HEITSKTEALDKLTKEQQKLSAANKELQNQLQEITTEHNQLTEEYNRLRELHNSVEGSYSDELLNSAKLRGQLEELQLLRTQNTINEEKLMDQQKRVQKLEALVQDNETDLEQLKVKRQELLTINKEMSELIVQLQNDICLAKAKAQGLDAENKLLKQEKLTYDTKYNQLEQQLSLEASEKNEERLLLAKHLSEKTKMYELTKQKLEDVQGDFEATQHKHATVLKELHRELNKYKRGITEPKTPISYCSNCQQAINGYPTENPQQRSHSRSSSHGSMHSGSRRASESSESETVASSATTVQQPPPQQDLQAVPSKKVLVERILRLQQATARQTERIEFLENHTAALVAEVQKKSKVVQHYMLRDQTAGALTTSRSDQNKSELVKYGNGIMAAIYGGGSSKTGGENKAMSLELSLEINKKLQAVLEDTLLKNITLKENLDVLGLEVDNLTRKLRSLEGSCK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..: . : .. .... . :: :. . : : *. . *:. : : :: : :*.* *. :: : * : :* * : . : : .*: : ::* : .: :::: : . : :* . :*: : :. . : ..*: * *.:***: *:*:. ** :* ::*** :*::* :*. *:.: : : :::**.*: : : * .*. : ** :* * ::. *:*: ***: * ::: .: :*:* *: .:::.::.:: :: *:: * : :* :.: * . ** :.*. : ** ::* : *: : * :* * .: . . . : : : :: *. * .:::: ::.::.*:: : * : *:* : :. *** :.:.::. .***.: ::: : :.. . *:.: :: .:* * . ::** * . : . . . ::*:::.:: : ::*:* :*:* ::* : :: : : :. .. :: . ***** **::: .: * .: .* ..*:. * .* :*:***:***:* **:.*:***:*:* ** *::**:*::* *:**:: :*:*::. ** ** .* : * ****::* . .:..* ::*:******:********************:.** *::.* :: : : ", "identical_positions": 169, "similar_positions": 290, "identity": "17.19%" }, { "cls_id": "homologset.agr.MGI:2445027", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A980-1", "uniprot_id": "D4A980_RAT", "id": "D4A980-1", "name": "Paracaspase", "aln": "MSLWGQPLQASPPPAVQQPLTASSGPSTAPPAGSTLNRLPEPLLRRLSESLDRAPEGRGWRQLAELAGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVPELSDFLQALEHTEVLQLLNPPGLKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPYGNSSELIFNTVHVKDAGFYVCRVNNNSTFEFSQWSQLDVCDVTEVSDSFQGSLDGVSESKLRICVEPQSQKLAPGSALLLQCVAIGSPVPHYQWFKDESPLAHETKKHYTVPYVDLEHEGTYWCHVYNDRDSQDSKKVEIIIG--------------RTDGAVECTEDELNNLGRPDNKEQ-TGQPLAKDKVALLIGNMNYWEHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMCNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGRQALEIRSSLSEKRALTDPIQGAPCSAEALVRNLQWAKAHELPESMCLKFQCGVHIQLGFAAEFSNVMIIYTSIVHKPPEIIMCDAYVTDFPLDLDIDPKHANKGTPEETGSYLVSKELPKHCLYTRLSSLQKLKEHLIFTVCLSYQYSGLEDTVEEKQEVSVGKPLIAKLDMHRGLGRKTCLQACPMPDETCHSSTSTSAGAGHFHSSQDSFHDVYHSQLGNSDSAMPPDRCHCSRTPHAFISNYPPHHYCQFGRS-NVPVETT---DEMPFSFSDRLMISEN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2TBA3-1", "uniprot_id": "MALT1_MOUSE", "id": "Q2TBA3-1", "name": "Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog", "aln": "MSLWGQPLQASPPLAVRQPPTASSGPSTSPPAGATLNRLPEPLLRRLSESLDRAPEGRGWRQLAELAGSRGRLRLSGLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQALEHTEVLPLLNPPGLKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPYGNSSELVFNTVHVKDAGFYVCRVNNSSTFEFSQWSQLDVCDVAEVTDSFQGSMDGISESRLQICVEPRSQRLVPGSMLLLQCVAIGSPMPHYQWFKDESPLTHETKKHYTVPYVDIEHEGTYWCHVYNDRDSQDSKKAEVTIG--------------RTDEAVECTEDELNNLGHPDNKEQ-TGQPLAKDKVALLIGNMSYWEHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMCNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGRQALEIRSSLSEKRALTDPVQGAPCSAEALVRNLQWAKAHELPESMCLKFQCGVHIQLGFAAEFSNVMIIYTSIVHKPPEIIMCDAYVTDFPLDLDIDPKHANKGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEHLIFTVCLSYQYSGLEDTVEEKQEVNVGKPLIAKLDMHRGLGRKTCFQACRMPDEPYHSSTSTSAGAGHFHSSQDSFHDVYHSHLGNADSGMPPDRCHCSRTPHTFISNYPPHHYCQFGRS-NVPVETT---DEMPFSFSDRLMISEN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UDY8-1", "uniprot_id": "MALT1_HUMAN", "id": "Q9UDY8-1", "name": "Mucosa-associated lymphoid tissue lymphoma translocation protein 1", "aln": "MSLLGDPLQALPP------SAAPTGPLLAPPAGATLNRLREPLLRRLSELLDQAPEGRGWRRLAELAGSRGRLRLSCLDLEQCSLKVLEPEGSPSLCLLKLMGEKGCTVTELSDFLQAMEHTEVLQLLSPPGIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPES---FQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIG--------------RTDEAVECTEDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIVFGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELPESMCLKFDCGVQIQLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEHLVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKTCFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFHGVYHSHPGNPSNVTPADSCHCSRTPDAFISSFAHHASCHFSRS-NVPVETT---DEIPFSFSDRLRISEK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BCW4-1", "uniprot_id": "A0A8M2BCW4_DANRE", "id": "A0A8M2BCW4-1", "name": "", "aln": "-------------------------MSESNESSLNINFLKESVLKRLCESLDKANN-KGWRKLGEIVKNDKRFKVSLEDMDMCSLKALKADGSPSRTLLKLIGDQGCIQEELMEFLQIMGHTEALQCLKPPGIQILLQPQSVSVIAGHNLRLSCYAVGASPVQFQWFKKTEEVRSSSSPDLVFSPVQIRDAGFYICRVNCGSTYEFSQWAQVDVLDVPTR----YGLVSMGSEVRLRVLIQPQPQKLLTGDLLYLECGAAGRLLPQYQWYRNGAPIKKANKRKFTVKNVLPEHQGRYRCEICCNNERTWSSEVDVVIANPCLSQMKEARIFPQISGAMECSEDDFLSINKDNSFEK----PYATDKVALLIGNLAYRNHPQLKAPMVDVYDLTNLLRQLNFKVVSLLDLTESEMRNAVEEFLSLLHKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSGNCLCVQSILKLMQEKETGLNVFLLDMCRKRNMHDDAMPNV-MLKVTANIVFGYATCQDAEAFELSSSGFTNGVFIKFLKERLLEDEKITVLLDRVAEDMGQFDPTKGKQALEIRSSLSERRSLTDPICHGGYSDATEAHNPLWSKAHELPESKVLDFECGVRIKMDFAAEFSNVLVIYTSIVKKPEEMQSCQAHITDLPLDLDVDPKLMNKETLEETGSFLLSGSLPQHCLYTRLSSLQKLKEELAFTVCLQVQFSSLDDLVQWNMHVNIGKPLTAKLDLYRPTRKNSCQVTCHMPHSPSTSPSHSPGSDRRFHSQEPCCPQPYANPYLNVCEHLHGAQAGYRDFQLNTDHAYQYMPLSPLTNPPSIPIETTDDIDDMQNDFINSLHLYKHP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. .:* * *.:*:**.* **:* : :***:*.*:. . *:::* *:: ****.*:.:**** ****:*::** ** :*** : ***.* *.***::* ::*:* :*:**: ::*.* *.* . **:**** .:*: ..:.:*:*..*:::*****:**** . *:*****:*:** *:. :. ** :*:: ::* .*:* .*. * *:* * * :*:***::: *: : .*: : * * **:* * *.: :.: *.:.:: *. : . *:**:**:: .:.: :. *: * *.*********: * :**:****:****:********:*********** ** ***:*** **.********************************* ******.************************ :**::* : ***************.*****:. **::**:*:****:*****:*******.******: . ***:***********:*:****: * : .:* *:******** *.*:***:*::.********::****** ** *: *:*::**:*****:*** ** * *****:*:* .**:***************.* *****. *:*.*:* *: : .*.:**** ****::* :::* :* *.. . *.: :... ::** : * . * . . : . : .. .:*:*** *:: .* : * : :: ", "identical_positions": 411, "similar_positions": 213, "identity": "48.24%" }, { "cls_id": "homologset.agr.MGI:2445030", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1I1-1", "uniprot_id": "A0A0G2K1I1_RAT", "id": "A0A0G2K1I1-1", "name": "", "aln": "MAKLWFKFQRCFRYFRRKPVRFFTLLAIYLTAGSLVFLHSGFVGQPS---VPQSQASPAAG--SPAEGGAELPFLGDLHLGRGFRDTVEASSIARRFG-PTFK---GKDTSERAKLG-DYGGAWSRALKGRVVREKEKEKEEERAKYIGCYLDDTQSRALRGVSFFDYKKMTVFRCQDNCAERGYLYAGLEFGAECYCGHKIQAANVSEADCDMDCKGERGSVCGGINRLSVYRLQLAQESARRYGSAVFRGCFRRPNNLSLALPVTVAMPNMSVDKCVDLCTEKEFPLAALAGTACHCGFPTTRFPLHDREDEQLCAQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPAKSKKLIALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDSAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWK---GKEWPEFVRNYAPWWATHTLDWLK-FGKTVLVVHFEDLKQDLFTQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTAEMRRTIAAYIRMVDTALRSRNLTGVPEAYGPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4PHA7-1", "uniprot_id": "WSCD2_MOUSE", "id": "D4PHA7-1", "name": "Sialate:O-sulfotransferase 2", "aln": "MAKLWFKFQRCFRYFRRKPVRFFTLLAIYLTAGSLVFLHSGFVGQPA---VPQSQASPAAG--SPVEG-AELPFLGDLHLGRGFRDTVEASSIARRYG-PTFK---GKDTSERAKLG-DYGGAWSRALKGRVVREKEKEKEEEKAKYIGCYLDDTQSRALRGVSFFDYKKMTVFRCQDNCAERGYLYAGLEFGAECYCGHKIQAANVSESDCDMECKGERGSVCGGINRLSVYRLQLAQESARRYGSAVFRGCFRRPNNLSLALPVSAAMPNMSVDKCVDLCTEKEFPLAALAGTACHCGFPTTRFPLHDREDEQLCAQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPAKSKKLIALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWK---GKEWPEFVRNYAPWWATHTLDWLK-FGKTVLVVHFEDLKQDLFTQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTAEMRRTIAAYIRMVDTALRSRNLTGVPDAYGPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2TBF2-1", "uniprot_id": "WSCD2_HUMAN", "id": "Q2TBF2-1", "name": "Sialate:O-sulfotransferase 2", "aln": "MAKLWFKFQ---RYFRRKPVRFFTFLALYLTAGSLVFLHSGFVGQPA---VSGNQANPAAAG-GPAEG-AELSFLGDMHLGRGFRDTGEASSIARRYG-PWFK---GKDGNERAKLG-DYGGAWSRALKGRVVRE----KEEERAKYIGCYLDDTQSRALRGVSFFDYKKMTIFRCQDNCAERGYLYGGLEFGAECYCGHKIQATNVSEAECDMECKGERGSVCGGANRLSVYRLQLAQESARRYGSAVFRGCFRRPDNLSLALPVTAAMLNMSVDKCVDFCTEKEYPLAALAGTACHCGFPTTRFPLHDREDEQLCAQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPGKSKQLIALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWK---GKEWPEFVRNYAPWWATHTLDWLK-FGKKVLVVHFEDLKQDLFVQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTADMQKTISAYIKMVDAALKGRNLTGVPDDYYPR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2BGL3-1", "uniprot_id": "WSCD2_DANRE", "id": "A2BGL3-1", "name": "Sialate:O-sulfotransferase 2", "aln": "MARSLLKIH---RYFRRKPVRFFSFILLYLTAGSLVFLHSGFSSDSSTAGIAGSGSDPLLSEGRGGTGGGSATSEGLGLLGRVFKETRRTP---RRFGPPWMKESRGQDAPEWAGRGFDHTSSWSHGAKGRTTKE----MDDGRAKYIGCYVDDTQKRALRGVSFLDYKKMTVFRCQDNCAERGYLYAGLEFGAECYCGHKIQAPNVSESECNMECKGEKSNLCGGPNRLSIYRLELSQESARRYGSAIFKGCFRRPDNVTLALPASAVMQNMSVDKCVDMCTEKEFSLAALAGDKCHCGFPTPLFNLHEHEDEELCLHRCTGEDFESCGNRDFFVVYQTQVQDNRCMDRRFLPTRSKHLMALASFPGAGNTWARHLIELATGYYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGKKEIETFDASILMIRNPYKALMAEFNRKYGGHIGFASQAHWR---GKEWPEFVKNYAPWWASHTLDWLK-YGKKVQVVHFEDLKRDLFSQLKGMVIFLGLEVSEDRLLCVEGQKDGNFKRSGLRKLEYDPYTVEMRATIDRLIKTVDMELRKRNLSGVPDEYRPR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXV9-1", "uniprot_id": "WCSD_DROME", "id": "Q9VXV9-1", "name": "WSCD family member CG9164", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MALQGWRFFGVSATIIIYIG------------------------------------------------GVLFLSMNNIPGSHP--------------KRPR---------------------------------IERFAEFPSFHSPRFPMPSR---KMTIRWCRDLKYINRDLP-IYADYKSDFYTALPSDVSAALQSLPALTALASFPGSGNTWLRYLLQQATGILTGSIYKDYGLLKTGFPAEN--VCNSSVLLVKTHEWGSKAWAPFSKAILLVRDPEKAIIAEFNRQSGGHIGFASPDRYKRTKGKYWQQFVSNKLKGWEMMNLSWARNFTGSIKVVFYDDLVHHTERELRSILDFLQFPINEQLMRCAIMRKEGIFRRK-KRLLSFDPYTESMRAEVQNRRRIVYGLLGRQEP----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:* *:. . :: * **: .: :: :** : . .* :. * : .: :: : * .: . . : *:::. * * *******:**** *:*:: *** *** * * .* :.** .*. .. .: :**** *.* .*. :**::*:* **::*****: *******: ::: ** * :** * * .*.* : : .: **.::** :. :* :: :* . : *: : *. :*:* *:*. * *.:**** .*: : : * * :: ", "identical_positions": 95, "similar_positions": 93, "identity": "16.21%" }, { "cls_id": "homologset.agr.MGI:2445031", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PSK5-1", "uniprot_id": "E9PSK5_RAT", "id": "E9PSK5-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------MEARPRPLPRPPDVGARQRRRAPGWALWGGREAAPGREPRPSPRAQARRPTPSCPLRAASCRPLRSRSRRRVLQRGPSMVMADGPRH---------------------LQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHSRKVVHRDLKAENLLLDNSMNIKIADFGFGNFFKTGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLSIAQIKEHKWMLIEVPVQRPILYPQ--EQENEPSIGEFNEQVLRLMHSLGIDQQKTIESLQNKSYNHFAAIYFLLVERLKSHR-----------------------SSFPVEQRLDGRQRRPSTIAEQTVAKAQTVGLPVTLHPPNLR---------------------------------------------------------LMRSTLLPQASNVEAFSFPASSCPA-----------------------------------------------------------------------------EAAFMEEECVDTPKVNGCLLDPVPPVLVRKGCQSLPSS-------------------------------------------------------------------------------------------------MMETSIDEGLETEG---------------------------EAEEDPSQAFEAFQATRSGQRRHTLSEVTNQLVVLPRAGKVFSMSDSPSLDSVDSEYDMGSAQRDLNFPEDSPSLKDIMLANQPSPRMT-PFISLRPA------------------------------------------NPAMQALSSQRREAHNRSPVSFREGRRASDTSLTQGIVAFRQHLQN----------LARTKGILELNKVQLLYEQIRSDADPTLTSTAPQLQ--DLSSSCPQEEISQRQESVSALSASMHPQLSPQRSLETPYLQHRLQKPSLLPKAQNACPMYCKEP-----------------PRSLEQQLQEHRLQQKRLFLQKQSQLQAYFNQMQIAERSYP-------GPTQQLALPHPETAPTPQQP---PSFSLTQALSPVLEPSSEQMRFSSFLSQYPDMQLQPLPSTPSPRAPPPLPSQLQQQQQPPPPPPPPPPQQPGATPASLQFSYQTCGLPSTTSSAPSYPASCHYPVDGAQQSNLTGAECPRSSGLQE--------ALSALPGLFDYEMVEAVDPQHNGVACPISR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFH6-1", "uniprot_id": "SIK2_MOUSE", "id": "Q8CFH6-1", "name": "Serine/threonine-protein kinase SIK2", "aln": "----------------------------------------------------------------------------------------------------MVMADGPRH---------------------LQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFGNFFKTGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLSIAQIKEHKWMLIEVPVQRPILYPQ--EQENEPSIGEFNEQVLRLMHSLGIDQQKTVESLQNKSYNHFAAIYFLLVERLKSHR-----------------------SSFPVEQRLDGRQRRPSTIAEQTVAKAQTVGLPVTLHPPNVR---------------------------------------------------------LMRSTLLPQASNVEAFSFPTSSCQA-----------------------------------------------------------------------------EAAFMEEECVDTPKVNGCLLDPVPPVLVRKGCQSLPSS-------------------------------------------------------------------------------------------------MMETSIDEGLETEG---------------------------EAEEDPSQAFEAFQATRSGQRRHTLSEVTNQLVVMPGAGKMFSMSDNPSLESVDSEYDMGSAQRDLNFLEDSPSLKDIMLANQPSPRMTSPFISLRPA------------------------------------------NPAMQALSSQKREAHNRSPVSFREGRRASDTSLTQGIVAFRQHLQN----------LARTKGILELNKVQLLYEQMGSNADPTLTSTAPQLQ--DLSSSCPQEEISQQQESVSSLSASMHPQLSPQQSLETQYLQHRLQKPNLLPKAQSPCPVYCKEP-----------------PRSLEQQLQEHRLQQKRLFLQKQSQLQAYFNQMQIAESSYP-------GPSQQLALPHQETPLTSQQP---PSFSLTQALSPVLEPSSEQMQFSSFLSQYPEMQLQPLPSTPGPRAPPPLPSQLQQHQQPPPPPPPPPPQQPGAAPTSLQFSYQTCELPSTTSSVPNYPASCHYPVDGAQQSNLTGADCPRSSGLQDTASSYDPLALSELPGLFDCEMVEAVDPQHNGVVSCLARET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0K1-1", "uniprot_id": "SIK2_HUMAN", "id": "Q9H0K1-1", "name": "Serine/threonine-protein kinase SIK2", "aln": "----------------------------------------------------------------------------------------------------MVMADGPRH---------------------LQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQ--EQENEPSIGEFNEQVLRLMHSLGIDQQKTIESLQNKSYNHFAAIYFLLVERLKSHR-----------------------SSFPVEQRLDGRQRRPSTIAEQTVAKAQTVGLPVTMHSPNMR---------------------------------------------------------LLRSALLPQASNVEAFSFPASGCQA-----------------------------------------------------------------------------EAAFMEEECVDTPKVNGCLLDPVPPVLVRKGCQSLPSN-------------------------------------------------------------------------------------------------MMETSIDEGLETEG---------------------------EAEEDPAHAFEAFQSTRSGQRRHTLSEVTNQLVVMPGAGKIFSMNDSPSLDSVDSEYDMGSVQRDLNFLEDNPSLKDIMLANQPSPRMTSPFISLRPT------------------------------------------NPAMQALSSQKREVHNRSPVSFREGRRASDTSLTQGIVAFRQHLQN----------LARTKGILELNKVQLLYEQIGPEADPNLAPAAPQLQ--DLASSCPQEEVSQQQESVSTLPASVHPQLSPRQSLETQYLQHRLQKPSLLSKAQNTCQLYCKEP-----------------PRSLEQQLQEHRLQQKRLFLQKQSQLQAYFNQMQIAESSYP-------QPSQQLPLPRQETPPPSQQA---PPFSLTQPLSPVLEPSSEQMQYSPFLSQYQEMQLQPLPSTSGPRAAPPLPTQLQQ-QQPPPPPPPPPPRQPGAAPAPLQFSYQTCELPSAASPAPDYPTPCQYPVDGAQQSDLTGPDCPRSPGLQEAPSSYDPLALSELPGLFDCEMLDAVDPQHNGYVLVN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F378-1", "uniprot_id": "E7F378_DANRE", "id": "E7F378-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------MVMADCHQKPA-------------------ALRGPVRVGFYDIERTLGKGNFAVVKLARHRITKTEVAIKIIDKTQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKNMLYLVTEYAKNGEIFDYLAKHGRLSEPEARRKFWQILSAVEYCHNRNIVHRDLKAENLLLDGHMNIKIADFGFGNFFQSGKPLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPSLPVLRQRVLEGRFRIPYFMTEDCEHLIRRMLVLDPSKRLSIGQIKEHKWMVMEVPVQRPMLYQQ--TTEGEAGVGEYNEQVLRLMHSLGIDQHKTVESLQNKSYNHFAAIYYLLVERLKAHR-----------------------CSFPVEPRLDARQRRPSTIAEQTLVKASSAAPQVSLLPQNVR---------------------------------------------------------LLRPPAVPQTS-ADSFTFPQSSCAA-----------------------------------------------------------------------------EHSLMEEEEVGTPKINGCMLDPLPPVAVRKSSASSPSN-------------------------------------------------------------------------------------------------MMETSIDEGIETEEP--------------------------DTEDDHTHVFNAYQTARFGQRRHTLSEVTNQPGIITSGGKLFSMGHNPSLGSVDSEYDMGSMHSDLSLLEDGPSLNEVVLANTPVTRLTPPFISARPA------------------------------------------NPTMQALSTQRRETHNRSPISFREGRRASDTSLTQGLVAFRQHLQN----------LARTKGILELNKV---YAQMGSGETPSLGLLSPQAHPHGLLDPALQEERGHQPDIALCSGGTHPALLSRRQSLEPQYLPHRIQKATLMANSPSSCQMFCKET-----------------PRSLEQQLQEHRLQQKRLYLQKQTQMQAYFNQMHIVEDPFAPCATMGHQDSGAPPQPQGSLAPAHQQPQSSPPFAHAQPLGPLMEPNPEALAYETYLGLYP--QLQPLPQS--------YPAQLQQ-------------------PEPLNYTYPPCDPSHSPSGEALYPEQYDYPLDPGQ---LPPPAEVSTAGYEG-------LALGDP--FLDSEMMETVDSQH-GFVLVN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M1P999-1", "uniprot_id": "A0A8M1P999_DANRE", "id": "A0A8M1P999-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------MVMAAQDQKP--------------------LQRAPVRVGFYDIERTLGKGNFAVVKLARHRITKSEVAIKIIDKTQLDAVNLEKIYREVEIMKLLDHPHIIKLYQVMETKNMLYLVTEYARNGEIFDYLASRGRLSEVDARKKFWQILSAVEYCHQRNIVHRDLKAENLLLDTHMNMKIADFGFGNFFRPGEPLTTWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPSLPVLRQRVLEGRFRIPYFMSEDCEHLIRKMLVLDPARRLSLSQIKEHRWMVQEVPSQRPVLYRQGLPCESKSGLGEHSEQVLRLMHSLGIDQQKTIESLQNKSYNHFAAIYYLLVERLKAHR-----------------------SSFPVEQRLHASQRRPSTVAEQTVVKTIAVPSQAGVPPQAAR---------------------------------------------------------QLRSPVLLQST-AETFTFPQSPASP-----------------------------------------------------------------------------DQTLMEED-VATPKVDGCLLDPLPPVVVRKVSGSLPSN-------------------------------------------------------------------------------------------------VMETSIDEGIEAEE-------------------------------EHTVPLAAFHTARFSQRRHTLSEVTNQPAAQP------LTDLNPSLSSMDSQYSMGSTQSDCSFPEESPALN-----STPAGSTAPVFLSMKPP------------------------------------------EACLQTLNPQ---GHNHSLVSFREGRRASDTSLTQGLVAFRHHIQN----------LARTKGFLELNKAQIVLGDGGACGNTMISPRELLEPHHPLNHQGEGRPCLGGKDPSTFTGKMHPYLLSRRQSLETQYLTQRLQRASQLASGLGSGQMFCKEAA----------------PRTLEQQLQEHRLQQKRLYLQKQSQVQAYFHQMQLAEDAYP--------------AQDPQISSSPQPS---PPFTRTQTLTPFLEPGISSLSYS---------------------------------------------------PKSARFPEWPPPPENLSNYTPSLPTEPQYAWSPAQPPLPPGKAETPS------------VQPAPEAPFLDCEMMETVEAPQ-GCVLVN----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W532-1", "uniprot_id": "Q9W532_DROME", "id": "Q9W532-1", "name": "non-specific serine/threonine protein kinase", "aln": "MSTCEAAAAGENGSQAKSEESQPPEDQKKKQPQHERNEKQLDKPPENLPQNGKTEAKGAEGACSHPPLDALRSSVLLDAGAASPSIDAIVACKDALLAQKLFASGGGSTPGPSPTSSAVGAGGISGKDLLKLKEPMRVGFYDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKVYREVEIMKRLKHPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTRRYTIDQIKRHRWMCPELLEHVLIAKYN-LGAERQTSVEPSEDILRIMAEYVGIGSDKTRASLKKNTYDHVAAIYLLLQDRVSHKKEQSNGLGASALASSTSASRMIYSSRNDHQPTQQQSQQQSKTISTSSILAKDQCHKRLSRHQTVLMSERNAHAGATPTVPDPGPGYYAKYGPLQLPLPLTGHSHLTGYLNGGGVEVDASGIPLPMRYTPLPTAASPAPSNCSSTSSRVGRHSLSSSSPRSHRPVAISLSIDNNPSLANLRCREMMEAGGGPVGAVGVPLASKQLHQTISEFIIKQSTEDCRALLQQSTAVAEGKDDPPKAESSVGGVPPPASTTPTSSTAGPESGSAPCPGEINGKTIKTMSSSSSFDSKANLGQSFRYKMSAEASKLFQTLQESPLPVEQRTKRRVHVGSTNGSGGDSGQETNDAKSNGDSRSEKKVLAQGSSSTDEGCETDQGNDPGSASQESKGSNGGGSGNANGGPTSHSSSDLTRLVGTTTSGQSHKMRSYASSSSSSGVLAGSAGSYSKSLSQNLSRGSSKSNCSGPYDSLDFALPSGKGSLPSCMGSSSMLATPTPASASPAGISSEHSSERSLYGSHNSCIHMPGALPLGLGLPQSSASTPTPNPTPPPNGGGVTFLDKRSPIHFREGRRASDGLVAQGLLSSGSLLGTSRVYGSYRYEQAKRHGWLEIQQLQQLQQEAAVGHSHPHAHQHPHQHPHPHPQAYGLEELCQFPNGQFYALPGKHHPLLTLPHHHAHPAQHHHGHHSLFHSGHQATPLLLEAAAGGDMYGHGCYAPPPPPPGLYTHHQLGVGMAVPMSPMQKPPLQQQLLQHRLLQQKRQLFQKQYALEAQLAGRHHHHQQHSHHHHHHFGHSLGPPPPPAPAPEHHLADELYELALLDRPRSGTPRLQHSMTMPGAHAFSQMNLKTSYISQSDQVPGAAPNGAGSGGSAAGVSCSAPPSTAPGTPTVKCKPTTPHGHSLDSDYHTSTPVLSLFTPN--------WQSLVKPLSESPILEISEHLESV---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : *:******** *:**********.*** **.*********:*** .**:*:****:*** *.**************.*:*:*:*** :******:*. **:.* ** *****:***:*** : :************* **:*******.*.*:.*: *:****************:** **::****:****************.:* **:***.******:**:.:******:****:*::* :: ***.*:** *: : : : * :..: .: : : . :**...** **::::*:*.**** ** :*:. :: . : . *::..*:: .:: :* . : :: . . . : . : : : * .** :..: . **. . . : .. .:* *** *:: . : . :: .:: :: :. :.. . . . .* .*: . .. . .: . . . . : * *. :. . . .::* : ********* ::**::: : . *: :* **::: : . : * .. :: : . : .. . : : . * :: : :** . * ::: : : . : .: . . * * :. . . . . . . : . : : ::: : . ", "identical_positions": 246, "similar_positions": 225, "identity": "17.37%" }, { "cls_id": "homologset.agr.MGI:2445040", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHR8-1", "uniprot_id": "D3ZHR8_RAT", "id": "D3ZHR8-1", "name": "tRNA wybutosine-synthesizing protein 3 homolog", "aln": "MGKFGPLRPPWRQYGCAHGEKGEFQSREPIPDRSLMDRSAEFGRWKAQSLSKAD-----LSRKGSVDEDAVEVVELLNSREEFFTTSSCAGRILLLDGSTNGPR------VQKQHCCWLLVTHKP--------------------CVKDDVMAALKGATSDAVLKFEPFILHVQCRTLQDAQTLHSVAIDSGFRNSGITVGKRGKIMLAVRSTHGLEVPL------THKGKLLVTEEYIEFLLTTANQKMEENKRRIGRFYNCLQHAVKRETISNSRSEIKEKNNPLCTPKNQRKQGKACDPSTTEDDGGEQ-LEGSDGWGIGAVLFLGDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BSA9-1", "uniprot_id": "TYW3_MOUSE", "id": "Q8BSA9-1", "name": "tRNA wybutosine-synthesizing protein 3 homolog", "aln": "-----------------------------------MDRSAEFGRWKAQSLSKAD-----LSRKGSVDEDAVEVVELLNSREEFFTTSSCAGRILLLDGSTEGSG------VQKQHCCWLLVTHKP--------------------CARDDVMAALKGATSEAVLKFEPFILHVQCRTLQDAQTLHSVAIDSGFRNSGITVGKRGKTMLAVRGTHGLEVPL------THKGKLMVTEEYIEFLLTIANQKMEENKRRIGRFYNYLQHALKRETISNSHSKIKERNNPLCTHKNRRSQGKAQGPSTTEDNGRE--LEDGDGLEISAALFLGDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IPR3-1", "uniprot_id": "TYW3_HUMAN", "id": "Q6IPR3-1", "name": "tRNA wybutosine-synthesizing protein 3 homolog", "aln": "-----------------------------------MDRSAEFRKWKAQCLSKAD-----LSRKGSVDEDVVELVQFLNMRDQFFTTSSCAGRILLLDRGINGFE------VQKQNCCWLLVTHKL--------------------CVKDDVIVALKKANGDATLKFEPFVLHVQCRQLQDAQILHSMAIDSGFRNSGITVGKRGKTMLAVRSTHGLEVPL------SHKGKLMVTEEYIDFLLNVANQKMEENKKRIERFYNCLQHALERETMTNLHPKIKEKNNSSYIHKKKRNPEKTRAQCITKESDEELENDDDDDLGINVTIFPEDY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6DHJ1-1", "uniprot_id": "TYW3_DANRE", "id": "Q6DHJ1-1", "name": "tRNA wybutosine-synthesizing protein 3 homolog", "aln": "-----------------------------------MD-GDSFQQWKNQCLNKCD-----FSKKGSVDEDISHVVSFINSQDRYFTTSSCSGRIILFDAVSDCPD------VQKQNCSWLFVTHQK--------------------CQMEDVVRGLEKSVGDATFKFEPFVLHVQCKQLEDAQLLHTVAINSGFRNSGITVGKKGKIIMAVRSTHCLEVPL------SHRSHVLVTHQYLDFLVGVANQKMEENLKRIQRFSECLQAALQPQ---EEKCSFKEADN-KTVYRRRRKRTQDVSVTDSSQNTQEHHENTEEEIDCDLLFLL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53177-1", "uniprot_id": "TYW3_YEAST", "id": "P53177-1", "name": "tRNA wybutosine-synthesizing protein 3", "aln": "-----------------------------------MAAQNAFEQKKRAILNEIDSTQPDLSPKGTIDELCLPIIDLINASADMVTTSSCSGRVSVFLEGTKSYNGEVKIGGKGQGGKWLYVTHDREKVIGWLDELKSKSEFSFELSGKEIPTEKVTGSIRYILYKYEPFILHVKCRDFQAASKLYNTAMSCGFRESGIGSNN----LVAIRINIKLDVPLGYLDETSGTLKFFVTPEYVSVLDSLSLSKFDENTRKMQALYDRIEKELINCAP-DVNSKVNITPIETKEERRERKKREGMERQRQLKSPQNVL------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : * *.: * :* **::** ::.::* .*****:**: :: . : * ** ***. . : : : *:***:***:*: :: *. *:. *:..***:*** .: ::*:* . *:*** : :.:** :*:..* : .*::** ::: : : :: : : . ..: :..*. : .. : ", "identical_positions": 55, "similar_positions": 76, "identity": "16.62%" }, { "cls_id": "homologset.agr.MGI:2445041", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JHY4-1", "uniprot_id": "WF15B_MOUSE", "id": "Q9JHY4-1", "name": "WAP four-disulfide core domain protein 15B", "aln": "MKLLGLSLLAVTILLCCNMARPEIKKKNVFSKPGYCPEYRVPCPFVLIPKCRRDKGCKDALKCCFFYCQMRCVDPWESPE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7FAP6-1", "uniprot_id": "F7FAP6_RAT", "id": "F7FAP6-1", "name": "", "aln": "MKLLSLPLLTVTILLCCNMAQAIFWRKKALSKPGFCPEFHLPCPFVLVPKCRRDRGCSGSLKCCFYYCQMRCVVPWDNSD", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.*.**:**********:. : :*:.:****:***:::******:******:**..:*****:******* **:..:", "identical_positions": 53, "similar_positions": 24, "identity": "66.25%" }, { "cls_id": "homologset.agr.MGI:2445044", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PWW6-1", "uniprot_id": "E9PWW6_MOUSE", "id": "E9PWW6-1", "name": "", "aln": "MSSVSEERRKRQHSIKEGLQFIQSPLSYPGTQEQYAVYLHALVRNLFNEGNDIYRECDWRGSLIQYSEALSIANYAKSEEILIPTEIIEKLRINRIACYSNMGLRDEVLEDCNAVLSVNASNCKALYRKAKALSDLGHYREAYDAVAKCSLAVPQDEHVIKLTQELAQKLGFKIRKAYVRAEHLLKAVPGDGAPKAVNYSVEDIEPDLLAPRQEALSVASLPTSSFSHVIGSELASVPIMPVTSVLQLQVDESPLPSTVFANGGKIPFTISDAFLDD-DIVLGDEIDALLDSAPETNDAVMSSTLVRGPLPTASAAPSLPFRTQSLLGTLPMGTRYP-EPSFADFFPPLTSSLEEFYSSLNSFSVTESKRDLCTSTAREGTPLNNSNSSLLLMNGPGNLLASENFLGITSQPRNDFGNFFGSVIAKPFSSGTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANVDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAADDECRYPGHCTFAYCQEEIDVWTLERKGAFSREAFFGGNGKINLTVVRILQEHHGEFTFLCEKCFDHKPRMISKRNKDNSTACSHPVTKHEFEDNKCLVHILRETTVKYSKIRSFHKQCQFDICRHEVRYGCVREDECFYAHSLIELKVWIMQSERGISHDDIAQQSKQYWRSLQASMPGVQVLGNQIMPGLLNMEIKFVCAQCLRNGQVIEPDRNRKYCSAKAQHSWTKERRAMRAMSFERKKWMNIRPLPTKKQMPLQFDLCNHIANRKKCQYVGNCSFAHSPEEREVWTYMKDNKIHDIEQFYELWLKNQKTEKSDETASHCSKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQDHISSEKHKEKVFHTEDDQYCWQHRFPTGYFSICERYINGSCTEGSSCKFAHGNAELHEWEERRKALQMKFKKARKDHLIAPNDNDFGKYSFLFKDLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZP12-1", "uniprot_id": "D3ZP12_RAT", "id": "D3ZP12-1", "name": "", "aln": "MSSVSEERRKRQHSIKDGLQFIQSPLSYPGTQEQYAVYLHALVRNLFNEGNDVYRECDWSGSLLQYSEALNIASYAKSEEILIPKEIIEKLQINRIACYSNMGLHDKVLEDCNAVLSVNASNCKALYRKAKALSDLRRYREAYDVVAKCSLAVPQDEHVIKLTQELAQKLGFKIRKAYVRAELSLKAVPGDGAPKAVNHSVEDIEPDLLTPRQEALSVVSLPTSSFSHVIGSELASVPIMPVTSVLQLQVDESPLPSTVFANGGKIPFTISEAFLDD-DIVLGDEIDALLDSAPETNDAVMSSTLVRGPLPTASAAPGFPFRAPSLLGTLPIGARYAPEPSFAECFPPLTSPLEDFYSSLNAFSVTESTRDLSTSTAREGTALNSSNSSLLLMNGPGSLFASDNFLGITSQPSNDCGNLFGSVIAKPFSSGTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANLDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAADDECRYSGHCTFAYCQEEIDVWTLERTGAFSREAFFGGNGKISLTVVKILQEHLGEFTFLCEKCFDHKPRMISKRNKDNSTACSHPVTKHEFEDNKCLVHILREATVKYSKIRSFHKQCQLDLCRHEVRYGCVREDECFYAHSLIELKVWIMQNERGISHDDIAQQSRQYWRSLEASLPGLQVLGNQIMPGLLNMEIKFVCAQCLRNGQVTEPDRNRKYCSAKAQHSWTKERRAMRAMSFERKKWMNIRPLPTKKQMPLQFDLCNHIANRKKCQYVGNCSFAHSPEEREVWTYMKDNKIHDIEQFYELWLKNQKTEKSDETSSHCSKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQDHISSEKHKEKVFHTEDDQYCWQHRFPTGYFSVCDRYMDGSCTEGSSCKFAHGNAELHEWEERRKALQMKLQKARKDHLIAPNDNDFGKYSFLFKDLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IWR0-1", "uniprot_id": "Z3H7A_HUMAN", "id": "Q8IWR0-1", "name": "Zinc finger CCCH domain-containing protein 7A", "aln": "MSNVSEERRKRQQNIKEGLQFIQSPLSYPGTQEQYAVYLRALVRNLFNEGNDVYREHDWNNSISQYTEALNIADYAKSEEILIPKEIIEKLYINRIACYSNMGFHDKVLEDCNIVLSLNASNCKALYRKSKALSDLGRYKKAYDAVAKCSLAVPQDEHVIKLTQELAQKLGFKIRKAYVRAELSLKSVPGDGATKALNHSVEDIEPDLLTPRQEAVPVVSLPAPSFSHEVGSELASVPVMPLTSILPLQVEESALPSAVLANGGKMPFTMPEAFLDDGDMVLGDELDDLLDSAPETNETVMPSALVRGPLQTASVSPSMPF-SASLLGTLPIGARYAPPPSFSEFYPPLTSSLEDFCSSLNSFSMSESKRDLSTSTSREGTPLNNSNSSLLLMNGPGSLFASENFLGISSQPRNDFGNFFGSAVTKPSSSVTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANIDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAAEEECRYSGHCTFAYCQEEIDVWTLERKGAFSREAFFGGNGKINLTVFKLLQEHLGEFIFLCEKCFDHKPRMISKRNKDNSTACSHPVTKHEFEDNKCLVHILRETTVKYSKIRSFHGQCQLDLCRHEVRYGCLREDECFYAHSLVELKVWIMQNETGISHDAIAQESKRYWQNLEANVPGAQVLGNQIMPGFLNMKIKFVCAQCLRNGQVIEPDKNRKYCSAKARHSWTKDRRAMRVMSIERKKWMNIRPLPTKKQMPLQFDLCNHIASGKKCQYVGNCSFAHSPEEREVWTYMKENGIQDMEQFYELWLKSQKNEKSEDIASQSNKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQGHISSEKHKEKVFHTEDDQYCWQHRFPTGYFSICDRYMNGTCPEGNSCKFAHGNAELHEWEERRDALKMKLNKARKDHLIGPNDNDFGKYSFLFKDLN", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*********:.**:**********************:************:*** ** .*: **:***.**.**********.****** ***********::*:****** ***:***********:****** :*::***.************************************* **:******.**:*:**********:*****:.*.***:.**** :********:**:**:* ***:**.***:*:*****:***:.:***** *:*****:* *********::**.*:****** ***.:*.:** : *******:*:**. ***:: :*****.**:* ****:**::**.***.***:****.**.************.*:**:*****:*** ** **:***.::** ** ***********************************:*********************************************::****.*******************.***************.***.::**** *** **********************************************:*********** ***:*:*********:***********:********.* ***** ***:*::**:.*:*.:** **********:***:************** ***:*********:*****:*****.**:****************************. *************************:* *:*:*********.**.***:: :*:..************************************.*******************************:*:**::*:*.**.******************.**:**::********.****************:", "identical_positions": 805, "similar_positions": 134, "identity": "82.82%" }, { "cls_id": "homologset.agr.MGI:2445051", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LEZ9-1", "uniprot_id": "A0ABK0LEZ9_RAT", "id": "A0ABK0LEZ9-1", "name": "", "aln": "MLPILKVCGKSGDYPSPAPPRPPGSLPRRRPRQKRRRLRSAAQEPPVVLNFSLKMADPTFAGTTNGTSLRGLRERLVAVAQELAEERRRKRG-LESSAVSLK--KSSCTPVLDGSVLKNDVKQQLAKERREEQKRQQEANKEKQLLEKEQKAKLQYEKQLEEKHRKLKEQKEKDERRRASAEEKRKQKQAEDKEKFKAVVSRTMERCNLIDKRQ-KRWSWEGSVMNTDKS-------------------------------------GKPENKRSSSMSRKENQLQTSGDLQHVNNRP---SMTKYVFRYVTVPMFTSE-ELKSSAMFCKPSAKAPVTAKLEVTPIKKVETPLKGDVEGPAKVVNLEIPPKITIEVPSPTNLEEPSEGDVEVKLQNMEDISKVKVEISPEADVKVSIDENIARYPKPNVEELPSVSMDASSSIEPSSTVSEDSFPSPSTASSSFVSVEISPVVSLDASPETSIDASPESSMDSGSMEVALGNNLEAPLQASEESYFDESVQEQP--------QNPEMDKRNVNLNLTTKKQAPCHIPCYRWPSSPALGWRPPSPLKA-LQSRKIRPPSPLPVSSRLSTKTSLSYRITPVQNILYVPNALGIIAAKKDNIQK-----------HMIQKESGYKSMP---SGEVAKKALVQVQHAAYEQKGKKEKERVQKEEIKQSIARKSEVMEKKLNEVPAGESSPRKD-EQREKDPTKPLLELPEDQKEQLQKGDSAMMNPHDSAEQRKKEQERIMLQNWQERLERKKRVEEIMKWTRKTDENTSKASEISSS--SEDDADDEDETGSEDSVEMLPSG-RKMSMKHKKFHK---YAKMKPQKLVFLQAGTGEVDTEKNVYFNGDVKDAKQKDPKYSTIQAKVSKISTKRPPTRPIRSRKIKEGGTTIRPTQSVTTS--HQWFCDKLIDLSHTTESPVVKTTPG-NNKQSSTDPKISHQGPQAPADHKKRVKAVSAPLTEVFSHLHIAGRATNLEHPFASSYSRLAFGGEVEDSDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AEY4-1", "uniprot_id": "MA7D3_MOUSE", "id": "A2AEY4-1", "name": "MAP7 domain-containing protein 3", "aln": "------------------------------------------------------MADPTFAATSSSTSFRGLHERLVAMTQELAEERRHKRG-INSSAGANK--RSSSTP--DGSVLKNDVKQQLAKERREQQKRQQEANKEKQLLEKEQKAKLQYEKQLEEKHRKLKEQKEKDQRRQASAEEKRKQKQAEDTEKFKAVVSRTLERCNRIDQRQ-KRWSWEGGVMNADKS-------------------------------------GKLENKRSSSLSRKDNRLHPRGDMQHVDNTP---GMTKYVFRYVTAPVFSSD-EIKSSAMFCKPSAKTPVAAKLEKITTKKLDASLRGHVEG-LSMMNIEIPPKITIEVPSPPKLEESSEADAEVRLQTMDDISKVKEDASQKVDIKVPTDENIARHPKPNVEELSPVSVDTSSSVELSSIVSVNSSPSLSTGSFSFGSVEISPVVSIDASLETNIDTSPELSMDSGNTKVASEIKTEAPLQARGESRLEASVEGQPEANVEGSPKNPEIDKR--NINLTTKKQPLCHIPCYRWPSSSALGCRPPSPLKA-LQTRKIRPPSPIPVSSKLSTKTSLSYKITPVQNVLYVPNSLGVIATKKETIQK-----------YPIKKEFGNRSMP---SAEAIKKAFIQIRHAAYEQ-SKNEKERLQKEETKQRIARKPEIMAEKLDKVPAEGSLPCQD-EQQDKNPTKTFLESPEVQKAELQKGDSAMMKSRDSAEQRKKEQE-NILQHWQERLERRK------------------ASEISFS--SEDEADDEGE--SEDSLEIFPSGGKMLSMKLKKFHK---YAKTKPQKLVFLQSGTDEVDTNKNVYFNGDMKAVKQKDPKYSMIQGKGSKLSAKKPPTRPIRSRKTKEGSTAIRPTQSASSNPNHKWVCDKVIDFNQT---PFLKTTLTKSNKESPADSKIACQGPQAHLDHRKRTKSVSVPLTNVLSHLHITGRASNLEHPFASVYSRLAFGKEAEESDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWC1-1", "uniprot_id": "MA7D3_HUMAN", "id": "Q8IWC1-1", "name": "MAP7 domain-containing protein 3", "aln": "-----------------------------------------------------MMADGAAAGAGGSPSLRELRARMVAAANEIAKERRKQDV-VNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVN-VEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSIVASP------EASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVK-GSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQ--ALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQ-REKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQKGD-AKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMPFNNAKKMTHKLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQEVVSRPSSKRMTSHTTKTRKADETNTTSRSSAQTKSEGFHDILPKSSDTFRQ------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QLL1-1", "uniprot_id": "A0A8M1QLL1_DANRE", "id": "A0A8M1QLL1-1", "name": "", "aln": "-------------------------------------------------------------MAEGATSLKGLRAQMAAAAQAQAEERRSQAGNSPTPAAPANTTKSQTKPVIDGASLRIDDKLRVAKERREEQEKQ-HAARETQLLERERKSRLQVERQMEERHKKLEEQRRKEEQRRAAVEEKRKQKLEEEKEHYEAVMRRTLERSQRVEQRQ-KRWSWSGLADSDNKN----------------------------------------DKRSSSTTNLKQTDSVISKRLSSS----------------------------SATLLNSPDKTRRSLAAPVDSGVLSRLLTPTQASLARSKSAAALSAEGGDAQESHLCPRSASASPMQPSARGPLRSRSSDRKKGPTTSVSADAISSMTQQKGEKEKRFTSP-----------------VGKRPASPSNRHRSPSPAPSASSTARAPSPGAAKQSPRVRPPSPSGLKQRPPSPQPSATSKPPPIQKAALTPTG---------PPTLRKR----------------------DSKPKDMTPMMPVAP--SSPETSTPSPVPAPAPKTKEESNSKAIAGTN---SAAEASKILAENRRLARE-----------------------------QKEKEEQLRIQKEEEEKLRKEEEKRLAEEERLRRAEEEKRLAEERKREEEEQTRLAEEE-------KQQMELEEQQRQAEQQKEREEAEAKAQEEAERQRQERARIMQQNQQERMERKKRIEEIMKR----------TRKTDQMDFKSDDVDGIPDEDGEGAEDQINCENKENEAVESECCG------EQTEEHHFPLKETDSDREETAVDINSQTHADNKENSNGPSTQDPLVDSPPPKSCLMEGSEFLNEDSKVNLVPGLNGKGG---PWSFEELIDLGVHAKTKPLMDDGSPEGPRVAFEEKTSSIHPAQPIEALSEM---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ...*:: *: ::.* :: *:*** : * . :* .* **: *: * * ::*:****::.:* .* :*.****:*:*::** *:*:**:::**:*::.*:::*: :.****:** :.*:: *:: **:** . :. * ***** * . .:. ::. **: . ::. . : : . : . : :: .:: :. :. : . :. : * . .. . . * . . .. . . * . . * . * :. : *. . :*. . . :. : . . :: . : *: .* *: . . : .***:* : : : * . * : . .: : :: : : .: .::: *: ::*::. .** : .: . :. :: : : * :: : * :.::.*:::::*: : *: ***:**:* . : . .: . : :. : : . .: ..: * *.. : . :*.: : .::. : . * .. : .: . . . . .. : ", "identical_positions": 96, "similar_positions": 229, "identity": "9.36%" }, { "cls_id": "homologset.agr.MGI:2445052", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ALH8-1", "uniprot_id": "A0A8I6ALH8_RAT", "id": "A0A8I6ALH8-1", "name": "TBC domain-containing protein kinase-like protein", "aln": "---MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQVLKTITHPRLCQYVDISRGKHERLVVVAEHCERSLEDLLRERRPASHSAVLCIAYEVLEGLQYLNKHGIVHRALSPHNILLDRKG-HIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIFKSTDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLGCVDDTLIVLAEEHGCLDIIKELPENALSILKKCLTFHPPKRPTPDELMKDQVFSEVSPLYTPFIKPASLFSSSLRCADLTLPEDISDVCKDIDDDYLAERSIEEVYYLWCLAGGDLEKELINKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSSLPHSNSNNELSAAASLPLIIRERDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMISFHDPELSNHLNEIGFIPD---VIYFIKFPTDVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESVNLFCWTPKSATYRQHAQPPRPASESSAVRSSSAPYFSAECTDPPKTDLSRESIPLSDLKSEVSPRISAEDLIDLCELTVTGHFKTPTKKTKSSKPKLLVVDIRNSEDFLRGHIAGSINIPFSAAFTAEGELSQGPYTTMLHSFKGKVIVIVGHVAKQTSEFAAHLVKMKYPRVCILDGGINKIKPTGLLTVPSPQI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BM85-1", "uniprot_id": "TBCK_MOUSE", "id": "Q8BM85-1", "name": "TBC domain-containing protein kinase-like protein", "aln": "---MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCERSLEDLLRERKPVSHSTVLCIAYEVLEGLHYLNKHGIVHRALSPHNILLDRKG-HIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIPKTTDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDVSERVKFLLTLGCVDDTIIVLAEEHGCLDIIKELPENVINILKKCLTFHPSKRPTPDELMKDQVFSEVSPLYTPFIKPASLFSSSLRCADLTLPEDISDLCKDIDNDYLAERSIEEVYYLWCLAGGDLEKELINKEIIRSKPPVCTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIRERDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESVNLFCWTPKSATYRQHAQPPKPASESSVVR-SSAPYFSAECTDPPKTDLSRESIPLSDLKSEVSPRISAEDLIDLCELTVTGHFKTPTKKTKSSKPKLLVVDIRNSEDFVRGHIAGSINIPFSAAFTAEGELSQGPYTTMLHNFKGKVIVVVGHVAKQTAEFAAHLVKMKYPRVCILDGGINKIRPTGLLTVPSPQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEA7-1", "uniprot_id": "TBCK_HUMAN", "id": "Q8TEA7-1", "name": "TBC domain-containing protein kinase-like protein", "aln": "---MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCERSLEDLLRERKPVSCSTVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRKG-HIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIFKTTDHMPSKKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTLIVLAEEHGCLDIIKELPETVIDLLNKCLTFHPSKRPTPDQLMKDKVFSEVSPLYTPFTKPASLFSSSLRCADLTLPEDISQLCKDINNDYLAERSIEEVYYLWCLAGGDLEKELVNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIREKDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKPSSDSSGGR-SSAPYFSAECPDPPKTDLSRESIPLNDLKSEVSPRISAEDLIDLCELTVTGHFKTPSKKTKSSKPKLLVVDIRNSEDFIRGHISGSINIPFSAAFTAEGELTQGPYTAMLQNFKGKVIVIVGHVAKHTAEFAAHLVKMKYPRICILDGGINKIKPTGLLTIPSPQI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F1V3-1", "uniprot_id": "E7F1V3_DANRE", "id": "E7F1V3-1", "name": "TBC domain-containing protein kinase-like protein", "aln": "---MQPLRDAELGASTFFASPLPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVIVAEHYEKSLKDLLKQRKPVSPEKVLQVAYEVLEGLEFMNKHGMVHRALSPNNVLLDRAD-KVKLAKFGLYHMTDHGADVDFPIGYPSYLPPEVIAQGCFYSSEPSINEAPQPSGPKTDVWSLGVLLFELCVGRQILQNIDISERMKFIITLGCMDDIITVLAEEHGCIDTIKDLPENVQALLRKCLTFLPSKRPTPSDLLGDAVFESISSEYTPYQSPVHLFSASPRCAYLQLPDDISELCRENGENYLSERAIDEVYHLWCLAGGDLEKELTNQEIIQSKPPICTLPKFILEDGESFGQGRDRSFLLDDTTVTLSLFQLRNRLKDVAGETYFPLLEDEQCSLPQSSSSNELSATVTLPLIIRERDTEYQLTRIVLFHRLLKAYPYKKNQIWKEARVDIPPLLRGLAWAALLGVEGDIQSKYDSIDKDTPIPTDRQIEVDIPRCHQYDELLSSPQGHVKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPNKPPSESNSFG-KTPSYYASEFQELTKTDLSREPLKLSELKAEVSPRISVEDLIDLCELSGPAFFKTPVKRARTGKPKILAVDIRSLEDFSRGHIYGSINIPYTSTFGPEGELLQCPASSSLAGYRLRVIVILSSVMKNAITFATHLVKVNFPRVCVLDGGMNKMKSTGLLTVPSPQI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4F8-1", "uniprot_id": "Q9W4F8_DROME", "id": "Q9W4F8-1", "name": "TBC domain-containing protein kinase-like protein", "aln": "MGTRERERECRLCAVTFFAKLHPGDVCGSNGLPLTPNSIAILGRAQKLKELQDEHLCQYLDVIRGKHERTIVVSEYLGLSLEDYAMRHPPLAIAQILRIFYQVACGINVLSRHHLVAHNVEPKHILLSSDGQRVKLFNYGLHHMTKGGAYVPFPIGNIRYMAPERLLG--------------LNGNVKSDVWSLALVMVELILQIELWPKLKLSNVVRKILAFGKSNGALEKIAREHQCHERYVQMDQRLRQLLESCLSVLPKRRPLPGELLEHPIFEEVLLDLK----KQKMQPLSPETEHLPL---------------LLRCPLSQIYHLWQLAGGDVQAELKKEGLIRSEAPILGLPQIVRLSGASVCPGRSQAQLMDDRVVPLRLKALLQRLSGLPAAVYFPLLHSPR--FPAHFAR----ELQELPLVIREKDIEYQFQRVRLFARLLQGYPHTAEQLQREAAVDVPPLLRGPIWAALLEVVP--NGSYAKIDKFTSTSTDRQIEVDIPRCHQYDELLSSPDGHRKLRRLLKAWVTAHPQYVYWQGLDSLTAPFLYLNFNNEELAFLSLFKFIPKYLQWFFLKDNSAVIKEYLSKFSQLTAFHEPLLAQHLASISFIPELFAIPWFLTMFSHVFPLHKILHLWDKLMLGDSSYPLFIGIAILRQLRSTLLTSGFNECILLFSDLPDIVMDGCVLESQKMYEATPKSITHRQHALRLQP---------------------PQALDIGVADVELKHLQQEQCPRISAKDVQFLLD---------------NSPAELALIDLRSVVEFGRVHVPHSINIPFATVQLGEQRLEALQVPQLEAQLRGKIVVCVSNIHQHSVEFSHFLVACGVQRTCILHKGFNVLHSIEPNILISN--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::..: * ****. * *************** **** * ** : . :****:*: ****** ::*:*: **:* .: * : :* : ::* *:. :.:* :* : :.*:::**. . ::** ::**:*** * * **** *:.** : .. *:*****.:::.** : :: .:.:*: :: ::::. :. : :*.** * : :: : :*..**:. * :** *.:*: . :*..: . : . * . * * * . .:.::*:** *****:: ** :: :*:*:.*: **::: .* *. **.:: *:** .*.* * * :**..: . .::***.. : :* : ***:***:* ***: *: ** ***:.**:. :*: :** **:***:** ***** * :..* *** *. .**********************:** *:**:*****.:**: ********* *********** **: .: ****** ******* **:***: ***: :**:* *::** .*.***: : :*:.: :.*******:****.*:**:**:*: **:***:***. **:.*************:* :: ** ** ::: **** *:**** :* *:. : *..*: * .****.:*: * : .. .:: :*:*. :* * *: *****:::. * .* . : :::* :. : ::: *: .** * *:*. *:* ::. : * ", "identical_positions": 341, "similar_positions": 244, "identity": "37.97%" }, { "cls_id": "homologset.agr.MGI:2445053", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AR48-1", "uniprot_id": "A0A8I6AR48_RAT", "id": "A0A8I6AR48-1", "name": "", "aln": "MVPPLPLSRGGAVKGQLGKSLGPLLLLLALGHTWTFREEPEDRDREVCSENKITTTKYPCLKSSGELTTCFRKKCCKGYKFVLGQCIPEDYDICAQAPCEQQCTDNFGRVLCTCYPGYRYDRERHQKREKPYCLDIDECATGNTTLCAHTCVNTMGSYHCECREGYILEDDGRTCTRGDKYPNDTGHEEKSENEVKAGTCCATCKEFSQMKQTVLQLKQKISLLPNNAAELGKYVNGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRHGLKGERGAPGPPGSPGPPGSFDFLLLVLADIRNDIAELQEKVFGHRIHSSAEDFP-LPQEFSSYPETLDFGSGDDYSRRT---EARDSEAPRNFYP-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3MI99-1", "uniprot_id": "CCBE1_MOUSE", "id": "Q3MI99-1", "name": "Collagen and calcium-binding EGF domain-containing protein 1", "aln": "MVPPPLPSRGGAAKRQLGKSLGPLLLLLALGHTWTYREEPEDRDREVCSENKITTTKYPCLKSSGELTTCFRKKCCKGYKFVLGQCIPEDYDICAQAPCEQQCTDNFGRVLCTCYPGYRYDRERHQKRERPYCLDIDECATSNTTLCAHICINTMGSYHCECREGYILEDDGRTCTRGDKYPNDTGHEEKSENEVKAGTCCATCKEFSQMKQTVLQLKQKMALLPNNAAELGKYVNGDKVLASNAYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRHGSKGERGAPGPPGSPGPPGSFDFLLLVLADIRNDIAELQEKVFGHRTHSSAEDFP-LPQEFSSYPETLDFGSGDDYSRRT---EARDPEAPRNFYP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXH8-1", "uniprot_id": "CCBE1_HUMAN", "id": "Q6UXH8-1", "name": "Collagen and calcium-binding EGF domain-containing protein 1", "aln": "MVPPPP-SRGGAARGQLGRSLGPLLLLLALGHTWTYREEPEDGDREICSESKIATTKYPCLKSSGELTTCYRKKCCKGYKFVLGQCIPEDYDVCAEAPCEQQCTDNFGRVLCTCYPGYRYDRERHRKREKPYCLDIDECASSNGTLCAHICINTLGSYRCECREGYIREDDGKTCTRGDKYPNDTGHE-KSENMVKAGTCCATCKEFYQMKQTVLQLKQKIALLPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKVFGHRTHSSAEEFP-LPQEFPSYPEAMDLGSGDDHPRRT---ETRDLRAPRDFYP-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A8WGB1-1", "uniprot_id": "CCBE1_DANRE", "id": "A8WGB1-1", "name": "Collagen and calcium-binding EGF domain-containing protein 1", "aln": "MIYPGR----GAS-----LSVAVALVLFSSGAPWTFREEKEDVDREVCSESKIATTKYPCVKSTGEVTTCYRKKCCEGFKFVLGQCIPEDYDVCAGAPCEQQCTDHFGRVVCTCYDGYRYDRERHRNREKPYCLDIDECANNNETVCSQMCVNTPGSYRCDCHSGFYLEDDGKTCTKGERAP----LFEKSDNVMKEGTCSATCEDFHQMKMTVLQLKQKMSLLSSNTEINKQMTNEKMMMTTNSFLPGPPGPPG---PAGTPGAKGSSGSPGQMGPPGLPGPRGDMGPIGPSPDLSHIKQGRRGPVGPPGAPGRDGMKGERGFPGPSGPPGPPGSFDFLLLMMADIRNDIAELQSKVFSRPLHSSFEDFPSAPDSWRDTPENLDFGSGEDYKSQSPPKSSRKRKLPRNLKNPDWPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * ** *:. *:*:: * .**:*** ** ***:***.**:******:**:**:***:*****:*:*************:** *********:****:**** *********::**:**********..* *:*:: *:** ***:*:*:.*: ****:***:*:: * **:* :* ***.***::* *** ********::**..*: : . . ::::*::****** ** *.*:**.***.* ** **** *****.***:*************************.* ***** *** *.************::*******:***.***.: *** *:** *:.: . ** :*:***:*: :: .:*. . **:: ", "identical_positions": 249, "similar_positions": 88, "identity": "59.71%" }, { "cls_id": "homologset.agr.MGI:2445054", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59110-1", "uniprot_id": "SENP1_MOUSE", "id": "P59110-1", "name": "Sentrin-specific protease 1", "aln": "--------------------------------------------------------------MDDTADGVKMDAGEVTLVNHGSTFRTHR---------------PPQSGFPEEQLLLSDQQSLPFR---QGTLDGSFTCSTRSPAYRPDYHSDNP-SSDSFLGSGDVR---TFGQSANGQWRN---STPASGSAPQKPRNSRSLCLETRKTSSGLSNTFVGKSNHHCHMSAYEKSFPIKPAPSPSWSGSCRRSLLSPKKTQRRHFSTAEETVQEEEKEIYRQLLQMVTGKQFCVAKP-TTHFPLR----LSRCLSSNKNSLKDSLLR-NGNSCASHVIGSDTSSSGSASI-LTAQEQLSHSAHSLSSGTPDVAFGSKDS-----DPHHHLAAPHQPNSLPASNTQSEGSDSVILLKVKESQTPAS--------------------------SPTFFQAELWIKELTSVYDSRARERLRRIEEQKALALQLQNQRLQEQEHAVLDSVELHLR-VPLEKEIPVTAAQETRKKSHQLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEK--GFPSVHAFNTFFFTKLKTAGYQAVKRWT--KKVDVFSVDILLVPIHLG-VHWCLAVVDFRRKSITYYDSMGGINNEACRILLQYLKQESVDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K1R8-1", "uniprot_id": "A0A0G2K1R8_RAT", "id": "A0A0G2K1R8-1", "name": "", "aln": "-----------------------MRNPLTATVFLPGSSPLGFCIFTTVSD-------VKRPEMEDTADGVKMDAGEVTLVNHSSAFRAHL---------------LPHSGFPEDQLALSDQQILPFR---QGTLHRAFTGSTSSAAYNPDYHSDNP-SSDSFLGSGDIR---TFGQSANGQWRN---STPASGSALQKPRNSRSLYLETRKTSSGLSNTFVGKSNHHCHVSAYEKSFPIKPAPSPSWSGSCRRSLLSPKKTQRRHFSTAEETVQEEEKEIYRQLLQMVTGKQFSVAKP-TTHFPLH----LSRCLSSNKNSLKDSLLR-NGNSCASHVIGSDTSSSGSASI-LTAQEQLSHSAHSLISGTPDVAFGSKDS-----ALHHHLSAPHQPDSLPASNPQSEGSDSVILLKVKESQTPASRYLSPLKRSTCPYIIPYSAVTDLLSSSPTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEQEHAVLDSVELHLR-VPLEKEVPVTAAQETRKKSHQLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEK--GFPSVHAFNTFFFTKLKAAGYQAVKRWT--KKVDVFSVDILLVPIHLG-VHWCLAVVDFRKKSVTYYDSMGGVNNEACRILLQYLKQESVDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P0U3-1", "uniprot_id": "SENP1_HUMAN", "id": "Q9P0U3-1", "name": "Sentrin-specific protease 1", "aln": "--------------------------------------------------------------MDDIADRMRMDAGEVTLVNHNSVFKTHL---------------LPQTGFPEDQLSLSDQQILSSR---QGHLDRSFTCSTRSAAYNPSYYSDNP-SSDSFLGSGDLR---TFGQSANGQWRN---STPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKP-TTHFPLH----LSRCLSSSKNTLKDSLFK-NGNSCASQIIGSDTSSSGSASI-LTNQEQLSHSVYSLSSYTPDVAFGSKDSGT-LHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTP--------------------------SSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLR-VPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEK--GLPSVHAFNTFFFTKLKTAGYQAVKRWT--KKVDVFSVDILLVPIHLG-VHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PWZ7-1", "uniprot_id": "A0A8M9PWZ7_DANRE", "id": "A0A8M9PWZ7-1", "name": "", "aln": "MFNKIYEWFGTGFASLRNGAPAGAVNADAARVDQDGTSRRKRSINCLNDGDQEEERVVKKFRMGDIMDTVKNAAEGVKTHGSNVAFWVKNSVSANSRNMLPTSPGPPQSGIPSGPAANSTSTSLWTEDKPHDRLQDTFVAPSSSVEWRTVTKSDSLRTEHSVTISKTSRRQVCMEHPPHEMYKANGHSVNLPSSSTPKPSPSPRLGRSLYHRPQSILSSPETSSGKATYTSLYEKTFPIRVVQS-SLPGSSNRLLR------ARARSTAQESVREEEKEVYRQLLVMVSEGQSSFLHDGSSHSSIRSHRDFSSFLSSSRSLLHCASPAGSGAGVSSYGLSSPPPSPQPGSS-QTSSALPSPGAASSLAEPPLWAHDLEPSAKGPDVPSAPSPAALQDTSSQDTQSSAHDGDSVIFVKEQQGKKPES-------------------------SSVPCFQAELWIKELTSLYDSRARERRRLIEEQEALASQLLRQRLSGEGRASPASVELKVR-VPLEKEVPIAAVIKKP----QPIKEEPEFPELTEEMENDVSRALRGGSQDEILSEGFRLTITRKDLQTLSHLNWLNDEVINFYMNLLVERSKQP--DLPSAYTFNTFFFPKLRSSGYSAVRRWT--KKVDIFSVDLILVPVHLG-VHWCLSVVDFRNKSITYFDSMGGNNDEACRILLNYLKQESEDKKGQKMETSGWSLKSKRPNEIPQQMNGSDCGMFTCKYAEYITKDRSITFTQKHMPYFRKRMVWEILNRKLLR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQH8-1", "uniprot_id": "Q8IQH8_DROME", "id": "Q8IQH8-1", "name": "Ubiquitin-like protease family profile domain-containing protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAFEKEIVEKSRYFDLITKECQDYPMAKTMPVLKQPE--------------------NFQEQEEDVVMAVQEKLKFFRKLTS----------------------------------------NGPAVPTPLKVVEKEDIGHKEI-PKVVKKVDRKTKLLQAIPAVFKHSHNRRFR-----------------------------------------------------------------------RSLFLRSNYIEQFRRWTDQKNKLNRKRLNEAHQLCLKAKHERIA-------CEIDRYKK-LILKQSVHVIEDIRIS----------SELIPLTKEHHDRLMELSKYP-LQQVIVAKFNLDICGSDIKILTSGGWLNDKIINFYMNLLVERSEKRPGTVPSVYAMSTFFVPRLLQSGFDGVKRWT--RKVDLFSMDLILVPVHQMLVHWCLVIIDLPAKTMLYYNSRGRGDPNLMRALVKYLQMESEDKLGLCLDTS--EFRIEDAQNVPQQDNMNDCGVFVCMFAEYLTRDAPITFSKKDMKYFRTKMVLELTGDQLWK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q02724-1", "uniprot_id": "ULP1_YEAST", "id": "Q02724-1", "name": "Ubiquitin-like-specific protease 1", "aln": "--------------------------------------------------------------MSVEVDKHRNTLQYHKKNPYSPLFSPISTYR----------CYPRVLNNPSESRRSASFSGIYKKRTNTSRFN--YLNDRRVLSMEESMKDGSDRASKAGFIGGIRETLWNSGKYLWHTFVKN-EPRNFDGSEVEASGNSDVESRSSGSRSSDVPYGLRENYSSDTRKHKFDTSTWALPNKR---------------------RRIESEGVGTPSTSPISSLASQKSNCDSDNSIT------------FSRDPFGWNKWKTSAIGSNSENNTSDQKNSYDRRQYGTAFIRKKKVAKQNINNTKLVSRAQSEEVTYLRQIFNGEYKVPKILKEERERQLKLMDMDKEKDTGLKKSIIDLTEKIKT---------------------------ILIENNKNRLQTRNENDDDLVFVKEKKISSLERKHKDYLNQKLKFDRSILEFEKDFKRYNEILNERKKIQEDLKKKK---EQLAKKKLVPELNEKDDDQVQKALASRENTQLMNRDN-IEITVRDFKTLAPRRWLNDTIIEFFMKYIEKS-------TPNTVAFNSFFYTNLSERGYQGVRRWMKRKKTQIDKLDKIFTPINLNQSHWALGIIDLKKKTIGYVDSLSNGPNAMSFAILTDLQKYVMEESKHTIGED----FDLIHLDCPQQPNGYDCGIYVCMNTLYGSADAPLDFDYKDAIRMRRFIAHLILTDALK-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .* * . : : . . . . . : . . :: *. . : :.. . . .::: . : *:: : . . :.:: .. : . ::: : * *:: * **** :*:*:*: : : *.. ::.:** ..* *:..*:** :*.:: .:* ::.*:: **.* ::*: *.: * :* . :: *: :: : . : *** * ***::.* : : * .: * :. :* :. : * ", "identical_positions": 45, "similar_positions": 107, "identity": "5.83%" }, { "cls_id": "homologset.agr.MGI:2445059", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JD3-1", "uniprot_id": "ODC_RAT", "id": "Q99JD3-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MSAS--NVSLLHETCRQVAAGGCAGLVEICLMHPLDVVKTRFQVQRSVTD----------PQSYKSLRDSFQVIFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLG----YMSLSPG-LTFPIAGLGSGLTEAVVVNPFEVVKVGLQVNRNMFTEQPSTFAYARQIIKKEGWGFQGLNKGFTATLGRHGIFNMTYFGFYYNVKDNIPSSKDPTLEFLRKFGIGFVSGTVGSVFNIPFDVAKSRIQGPQPVPG-EIKYRGCFKTMETVYREEGILALYKGLLPKVMRLGPGGGVMLLVYEYTYAWLQENW-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZ09-1", "uniprot_id": "ODC_MOUSE", "id": "Q8BZ09-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MSAS--NVSLLHETSRQVAAGGSAGLVEICLMHPLDVVKTRFQVQRSVTD----------PQSYRTVRGSFQMIFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLG----YMSLSPG-LTFLIAGLGSGLTEAVVVNPFEVVKVGLQVNRNLFKEQPSTFAYARQIIKKEGLGFQGLNKGLTATLGRHGIFNMVYFGFYHNVKNIIPSSKDPTLEFLRKFGIGFVSGTMGSVFNIPFDVAKSRIQGPQPVPG-EIKYRSCFKTMEMIYREEGILALYKGLVPKVMRLGPGGGVMLLVYEYTYAWLQENW-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQT8-1", "uniprot_id": "ODC_HUMAN", "id": "Q9BQT8-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MSAKP-EVSLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATD----------PNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLG----YVSLSPA-LTFAIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPG-EIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSWLQENW-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9V3T2-1", "uniprot_id": "Q9V3T2_DROME", "id": "Q9V3T2-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MAGQQHDISHAKRAAFQVLAGGSAGFLEVCIMQPLDVVKTRIQIQATPAPNAAAL----GEVHYNGVFDCFAKMYRHEGISSYWKGIMPPILAETPKRAIKFLVFEQTKPLFQ----FGSPTPTPLTFSLAGLTAGTLEAIAVNPFEVVKVAQQADR--QKKMLSTFAVAKGIIQQDGLGFSGLNKGITATMGRNGVFNMVYFGFYHSVKNVVPEYKESHLEFLRKVTIGFLAGTLACFVNIPFDVAKSRIQGPQPVPG-QIKYRGTLSSMGIVYREEGFRALYKGLVPKIMRLGPGGAILLLVFEYSYDYLLHNYS----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLF1-1", "uniprot_id": "Q9VLF1_DROME", "id": "Q9VLF1-1", "name": "Mitochondrial 2-oxodicarboxylate carrier", "aln": "MATRS-EETVRSLAHWQFLAGGLSGFIEIICFHPLDVVKTRMQIQGAHPFG--------GEVVYTCPLDAIVKIYRYEGLSSLWKGIVPPICVETPKRGGKFLMYESLKPYFQ----FGAPQPTPLTHAMSGSMAAILESFLVNPFEVVKITQQAHR---GKRLKTLSVVKYIIKHDGYGIKGLYRGITALVARNAVFHFGFFGFYNALKDIVPSPEDKTYNILRKVIIAGLASSLACVMSVTLDMAKCRIQGPQPVKG-EVKYQWTISTIKSTFKEEGFRSLFKGLGAMILRVGPGGAMLLVTYEYLFEFLKSQNI----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03028-1", "uniprot_id": "ODC1_YEAST", "id": "Q03028-1", "name": "Mitochondrial 2-oxodicarboxylate carrier 1", "aln": "MTS---IDNRPLPFIYQFTAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCLTKIVKKEGFSHLYKGITSPILMEAPKRAIKFSGNDTFQTFYKKIFPTPNGEMTQKIAIYSGASAGAVEAFVVAPFELVKIRLQDVN---SQFKTPIEVVKNSVVKG--GVLSLFNGLEATIWRHVLWNAGYFGIIFQIRKLLPAAKTSTEKTRNDLIAGAIGGTVGCLLNTPFDVVKSRIQ---RSSGPLRKYNWSLPSVLLVYREEGFKALYKGFAPKVMRLAPGGGLLLVVFTNVMDFFREVKYGKKQ", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q99297-1", "uniprot_id": "ODC2_YEAST", "id": "Q99297-1", "name": "Mitochondrial 2-oxodicarboxylate carrier 2", "aln": "MSSD--SNAKPLPFIYQFISGAVAGISELTVMYPLDVVKTRFQLEVTT---PTAAAVGKQVERYNGVIDCLKKIVKKEGFSRLYRGISSPMLMEAPKRATKFACNDQYQKIFKNLFNTN--ETTQKISIAAGASAGMTEAAVIVPFELIKIRMQDVK---SSYLGPMDCLKKTIKNE--GIMGLYKGIESTMWRNALWNGGYFGVIYQVRNSMPVAKTKGQKTRNDLIAGAIGGTVGTMLNTPFDVVKSRIQSVDAVSSAVKKYNWCLPSLLVIYREEGFRALYKGFVPKVCRLAPGGSLMLVVFTGMMNFFRDLKYGH--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *. :*. :*. *: : ********:*:: * ..: : : **: ::** .*: *:***. ** : : :* :. *: : ***::*: * . . .. : : : *. .* .*: : : *: ::: :**. ::. :* : : ... . :..::. ... .:*:.*.*** . **. : :: ::***: :*:**: . : *:.***.::*:.: :: ", "identical_positions": 58, "similar_positions": 99, "identity": "18.07%" }, { "cls_id": "homologset.agr.MGI:2445060", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q569B5-1", "uniprot_id": "LRC14_RAT", "id": "Q569B5-1", "name": "Leucine-rich repeat-containing protein 14", "aln": "MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTAVLRELVHTWPFPLLSFQQLLQECAHCSRALLQERLSTESMQAVILGLTARIHAREAEAGTQPVCRKHTLRVLDMTGLLDDGVEQDPGTMSMWDCTAAVARTCIAQQQVGTAKPGLSPVPVEIRVDLRVNRASYTFLREALQSSVDSLLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRIDLRFNNLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFICLRELSIGSSLLSGRLDQLLSTLQRPLESLELAFCALLPEDLRFLAQSSHAAHLKKLDLSGNDLSGNQLTPFQGLLQAVAATLLHLELTECQIADAQLLATLPTLTRCASLRYLGLYGNPLSMAGLKELLRDSVIQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTTDIYGRLAADYFNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VC16-1", "uniprot_id": "LRC14_MOUSE", "id": "Q8VC16-1", "name": "Leucine-rich repeat-containing protein 14", "aln": "MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTLVLRELVHTWPFPLLSFQQLLQECAHCSRALLQERLSTESMQAVILGLTARIHTQETEAGTQPLCRKHALRVLDMTGLLDDGVEQDPETMSMWDCTAAVARTCIAQQQGGTAEPGLSPVPVEIRVDLRVNRASYTFLREALQSSVASPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRIDLRFNNLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFMCLRELSMGSSLLSGRLDQLLSTLQRPLESLELAFCALLPEDLRFLAQSSHAAHLKKLDLSGNDLSGNQLTPFQGLLQAVATTLLHLELTECQLADAQLLATLPTLTRCASLRYLGLYGNPLSMAGLKELLRDSVVQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTTDIYGRLAADYFSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15048-1", "uniprot_id": "LRC14_HUMAN", "id": "Q15048-1", "name": "Leucine-rich repeat-containing protein 14", "aln": "MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQLLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLLDDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGSSLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTTDIYGRLAADYFSL", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************************** ********************************** ***************:*: *. *.***:****:****************** ******************** *:*:** :*:***:***********:******:*** * ********************************:********************************************************** ******:***************** *********************:*.*****************.**:******** *:***********:**:******* **:*************************** ************************************************************************.*", "identical_positions": 455, "similar_positions": 24, "identity": "92.29%" }, { "cls_id": "homologset.agr.MGI:2445062", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DEG0-1", "uniprot_id": "B5DEG0_RAT", "id": "B5DEG0-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGEYVLCSWKDQLWPAKVLD-------------RSESPSDSKRKKTLSVEVEILSLDEKITVESKDTKVLTKSAVEAIMSSLTVQSEVSFTPTEETAYERSLKMALEIVEERTNQSHESMAEE--------------------------------------------------------------------------------------------------------------------------------------------------QHMATASENVPQQPPDSPPHKKFRKLESNLQ------EDSASMLLCSESDDSLSDEKLQVHTTSENMPSEVEMKS-ENLSCCQTYPSFSDDDDKKEEKKKIDISAIMSVNLSLKEESEFIKEEKFVP-----SSEDLAVP-----------------------------------------------------------------------------------KEESQDILPDAP-AVSSECFIVSENNMEDPGEGPSNQNPGSYGSQSQSTVESDVGAETSTAGCSGDYQVSLPAR-------DTVNSDLL-LQRLDLEDLEEEARASGKLLSLNPACAAALEND------------------DEDDDEDLPRFILRYETRAFET--GMIVWFKYQKYPFWPAVIKSIRRKERKASVLLVEADMNPQK---RGVRVSLRRLKKYDCKEKQALVEKAREEYKESIDWCVSLICDYRVRLGCGSFTGSFFEYYAADISYPVRKIIKQDTFRNIFP--------KLYNEDAGEQLPVASHAKRVSFRKILPDRMKPARDRANKNLVDFIVNAKGTEDHLLGILKGTKKSKWLKSFLNAKSFTPCIETYFEDEDQLDEVVKYLQEIYKQIDQKMLT--LIKDDKIKFVLEVLLPEAIICSISAVDGLDYEAAEAKYLKGPSLGYRERELYDSKILFEKRRRSLPNEGR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VA55-1", "uniprot_id": "PWP3B_MOUSE", "id": "Q4VA55-1", "name": "PWWP domain-containing DNA repair factor 3B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGKYVLCNWKDQLWPAKVLD-------------RSESPSESKRKNTSSLEVEILSLDEKITVESTDTKVLSKSAVEAIMSSLAVQSEVIIAPREETAYERSLKMALEMVKEGTNLSQESMSEE--------------------------------------------------------------------------------------------------------------------------------------------------QPTATASENVPEQPPDSPPHKKFRKLESNTQ------EDSASILLCSESDDSMTDDKLQVHTTGESMPSEMDTKATENLGCCQTDPSLADEDDKKEEKKKIDISAIMSVNLSLKEESEYIKEEKFVP-----SSEDLTVP-----------------------------------------------------------------------------------KEESQDILPEAPLAVSSECSIVSENNMEDPGEGPSNQNLVSYANQNQSSVESDVGAETSTAGCSGDFQVSLPTR-------DTVSSDLL-LQRLDLEDLEEEARASGKLLSLNPASAAALEND------------------NEDDDEDLPRFILHYETRAFET--GMIVWFKYQKYPFWPAVIKSIRRKERKASVLLVEADMSPQK---KGVRVSLRRLKKYDCKEKQALVEKAREEYRESIDWCVSLICDYRVRLGCGSFTGSFFEYYAADISYPVRKIIKQDTFRNIFP--------KLYNENVGEQLPMASQAKRVSFQKILPDRMKPARDRANKNLVDFIVNAKGTEDHLLGILKGTKKSKWLKSFLNAKSFTPCIETYFEDEDQLDEVVKYLQEIYKQIDQKMLT--LIKDDKIKFVLEVLLPEAIICSISAVDGLDYEAAEAKYLKGPSLGCRERELYDSKILFEKRRRSLPNEGH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5H9M0-1", "uniprot_id": "PWP3B_HUMAN", "id": "Q5H9M0-1", "name": "PWWP domain-containing DNA repair factor 3B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MESEYVLCNWKDQLWPAKVLS-------------RSETSSNSKRKKAFSLEVQILSLDEKIKLDSTETKILNKSQIEAIAASLGLQSEDSAPPTEETAYGRSLKVALGILNERTNLSQASTSDE--------------------------------------------------------------------------------------------------------------------------------------------------EEITMLSQNVPQKQSDSPPHKKYRKDEGDLPGCLEERENSACLLASSESDDSLYDDKSQAPTMVDTIPSEVETKSLQNSSWCETFPSLSEDNDEKENKNKIDISAVMSVHSAVKEESACVKDEKFAPPLSPLSSDMLIMPKA--------------------------------------------------------------------------------LKEESEDTCLETL-AVPSECSAFSEN-IEDPGEGPSN--PCLDTSQNQPSMESEMGAAACPGSCSRECEVSFSASNPVWDYSHLMSSERN-FQRLDFEELEEEGQASDKSLLPSRINLSLLDDD------------------EED--EELPRFILHYETHPFET--GMIVWFKYQKYPFWPAVIKSIRRKERKASVLFVEANMNSEK---KGIRVNFRRLKKFDCKEKQMLVDKAREDYSESIDWCISLICDYRVRIGCGSFTGSLLEYYAADISYPVRKETKQDTFRNKFP--------KLHNEDAREPMAVTSQTKKMSFQKILPDRMKAARDRANKNLVDFIVNAKGTENHLLAIVNGTKGSRWLKSFLNANRFTPCIETYFEDEDQLDEVVKYLQEVCNQIDQIMPT--WIKDDKIKFILEVLLPEAIICSISAVDGLDYEAAEAKYLKGPCLGYRERELFDAKIIYEKRRKAPTNEAH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PVE2-1", "uniprot_id": "A0A8M1PVE2_DANRE", "id": "A0A8M1PVE2-1", "name": "", "aln": "MVAGMSSSDESLKRQRNPHRTCRTDSTQVNEPVSGGTESITHNKRTTAPQDLILVKSCGRRATENKPQAANQNAPPCLRKSRHQVTNINGCVSKKSHQPEQVLPRKIATPKYQIKTAYKGRRKKNVEASEKKVAASKAKLDVLDNLCSEQHLSSQKPKRTHHQNSKRTQNHQTPSDVSTGVYTCTTLSPCRCKEDSCCHTNRPQAPLQDRLQFTSLLSSTSNSDLKSLSPQTGQNSCVPHSEPDVLKSSLEKRPPTDASPSPQRARGRPKGNNNKVQEDPSSFSPVKHSRESTECPVEYPKRFLHSSSDLQCLSPQTAENSFAPNNHQNARKSSLKKRPPADALPSPQRARGRPKRNNNKVQEDPSSSSPVKHSRESTECPVEYPKRFLHSSSDLQCLSPQTAENTCAPNNYQNARKSRLKKRPPADALPSPQRARGRPKGSKNKKVQERPSASPSEKYSRKHEMPLVESCSQKHLSSPWNSHLQPLKPKTDDNSFAPYNDPNARESQQEKRPPADASSSTPSRPRAGPKGSTTKKIQKKSSISPPVKCSRKFTECLAASHTPKQKRLQSSPLLSSTPSSHHLPLIPLRADNNPTPNATKSRLKKRPPADASPSTPQRPRGRPKGSMNKKVQEGASVSPPVKRSRKFTECLAESHTPKQKRLKSSPLLSSTPSSHLQPLTSKREDNNPAPNATKSRLEKRPPADASPSTPQRTRGRSKGSTNKKVQEGASVSPPVKRSRKSTEFPAEMQTLSSPCSENQEPEPNESDQTMSSDLSIELSLHEDPHLLNHSLFMQEEKDDQDDDDDDEELPSFLGQDSKKPLSISEGLCVWCKMWKYPYWPAVVKSVNRKNKKASIIFIDCDLSDQKRAKKGFTVSLRNLKPFDCEDYEKLVDMAKEKYGSAITWSVELISDYRIRIGCGSFSGSFIEYCAADISCPVRRKYSEGKSVLTFPSQEILGEKCDISENSAEDICAEDQDELLSQKRNLPDRAKAARTRANEQLVDFIIRGK-VENHLLAIIS--ESSAWMQALQKPFRQVVCPVLYLEDEGQVDKVYQYLHDLCETAPQINTSPENVQVVRVRLILDVLLPKAIIYAIAGVHNLSLEKAEEKYHKGPRFSNRERQEFDMMIERQMKLKEITQRHRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. . .. . ::....*. *.::. :.: : : :. * :.:. :: :.. : :* :.: :** :. .* : * *. : :: :. * . : * . .::* :: . **..* ** * . *: :. .. *:: . . .. : * . ..* . . . *: . *:: . . :: : : .: ** * . : :*. .: : . *: *. *. . . .: : * . . . : .*... . :: :. *: * * . *.: : . *.:* ::* *:** *: : ..:.:. *: ** * ***:****:**:.**::***:::::.::. :* :*. *.:*.** :**:: : **: *:*.* .:* *.:.**.***:*:*****:**::** ***** ***: .:.. ** .*: * : .: : :* :: **** *.** ***::*****:..* .*:***.*:. : * *:::: :. . * *:***.*:*:* :**::: : * : :: :::::*:****:*** :*:.*..*. * ** ** *** :. ***: :* * : : : .:. : ", "identical_positions": 163, "similar_positions": 249, "identity": "14.26%" }, { "cls_id": "homologset.agr.MGI:2445066", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LWA0-1", "uniprot_id": "A0ABK0LWA0_RAT", "id": "A0ABK0LWA0-1", "name": "Homeobox-containing protein 1", "aln": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRR-----------SSYGGSSYG---NSTNNVPASSSTATASTQTQHSG--MSPSPSNSYDTSP---LPCTTNQNG-RENSDR---LSTSNGKMSPSRYHVN-SMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDP-EWRQTPPPVSATPGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIE-----AAILESHGIDVQSPGGHSNSDDVDGNDYSEQ----------------------------DDSTSHSDHQDPISLAVEMAAVNHTILALARQG--ANEIKTEALDDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BJA3-1", "uniprot_id": "HMBX1_MOUSE", "id": "Q8BJA3-1", "name": "Homeobox-containing protein 1", "aln": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRR-----------SSYGGSSYG---NSTNNVPASSSTATASTQTQHSG--MSPSPSNSYDTSP---LPCTTNQNG-RENNDR---LSTSNGKMSPSRYHAN-SMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDP-EWRQTPPPVSATPGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANI------AAILESHGIDVQSPGGHSNSDDVDGNDYSEQ----------------------------DDSTSHSDHQDPISLAVEMAAVNHTILALARQG--ANEIKTEALDDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NT76-1", "uniprot_id": "HMBX1_HUMAN", "id": "Q6NT76-1", "name": "Homeobox-containing protein 1", "aln": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRR-----------SSYGGSSYG---NSTNNVPASSSTATASTQTQHSG--MSPSPSNSYDTSP---QPCTTNQNG-RENNER---LSTSNGKMSPTRYHAN-SMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDP-EWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIE-----AAILESHGIDVQSPGGHSNSDDVDGNDYSEQ----------------------------DDSTSHSDHQDPISLAVEMAAVNHTILALARQG--ANEIKTEALDDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BL53-1", "uniprot_id": "A0A8M2BL53_DANRE", "id": "A0A8M2BL53-1", "name": "Homeobox-containing protein 1", "aln": "------------MSHYTDEPRFTIEQIDLLQRLRRTGMTRPEIVHALDTLERLDREHGDKFGRRGPSDSIATNSTTSSTTPTSN---NASNATMATSSTTSTATQTQFPGN-LSPSPSNSYATSPPAVLPSPVSLVA-LAQNGRDALAATPNGKLSPNRYTVNSSVAVRTYTLEGSEEDLDIDDKVEELMRRDSSLVKEEIKAFLGNRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTTPGATLNMRPTPVSLEEM-EWRQTPPPISSAPGSFRLRRGSRFTWRKECLAVMESYFSDNQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIGSFFQEATILESHGIDVQSPGGHSNSDDVDANDYSEQGCDVAYFEKRGVNRPFGYYRLEPTSPTQDDAGNHADHQDPISLAVEMAAVNHSILALSRPGGVASEIKTEAIDDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M2BH68-1", "uniprot_id": "A0A8M2BH68_DANRE", "id": "A0A8M2BH68-1", "name": "Homeobox-containing protein 1", "aln": "------------MSHYTDEPRFTIEQIDLLQRLRRSGMTKQEILHALDTLDRLDREHVEKFGHRHAHGGTSAINHSSNATTSSNSCTTSSNNLTASSSTTSTATQTGFRGNGLSPSPSNSYETSPPPTAPTSMPVVAPLVQNGRDALASMSNGKLSPPRFTVS-NVSSRAFPFEPPDEEMDIDDRVEELMRMDSAIIKEEIKAFLGNRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTTPGATLAMRPTPMALEDIVEWRQTPPPISSTQGSFRLRRGSRFTWRKECLAVMESYFNDNQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIE-----AAILESHGIDVQSPGGHSNSDEIDGNDYGEPVAADQVLG-------------------MDDNTGPNEHQDPIALAVEMAAVNHSILALARQGGSASDIKTEVLDDE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***********************:***: **:***:**:***:** :***:* :* .: . .::* *:***::::*** . * :******** *** * . . :. * : .***:** *: .. .:. *::.:* .:*::*:**:****** **:::********.************************************************.***** ***:*:.:*: ********:*:: *:***********************.:******************************************************* *:*******************::*.***.* ** . :*****:**********:****:* * *.:****.:**:", "identical_positions": 294, "similar_positions": 76, "identity": "61.25%" }, { "cls_id": "homologset.agr.MGI:2445069", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LS67-1", "uniprot_id": "A0ABK0LS67_RAT", "id": "A0ABK0LS67-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKAAGG---AAPAAESCPSAPAG--VSTPAGVEDLSKVTDEELLQWSKE------------------DLIRSLRRAEAEKVSAMLDHSN-------------LIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKELEVKQEEVVKENMELKELCVLLDEEKGTG----------CAGSRCSIDSQASLCQLVASAAPYVRDVGDGSSTSSTGSTDSPDHHKHHAS-------GG---SPEHLQ----KPRSEG-----SPE-HNKHRSTSPEHLHKPRASGTPDHPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPEMLPKHKLS-----GSPEHFQKHRPGGSPEHARHSGGSPEHLQKHALGGSLEHLPRAR---GTSPEHLKQHYGGSPDHKHAGGGGGSGG---GSREGTLRRPAQEDSSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQATQNRSQPPTRNSSNMEKGWGPRARRVLQWWQGCRGIGRCLPSLPGSFRLSSGADGNNSSPNSPASFSGHTTPSQQPEPVVHSLKVLDVEETVDRQQGKEYDHDLSETEKAIVREMCNVVWRKLGDAAGSCPGIRQHLSGNQYKGPM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SP85-1", "uniprot_id": "CC85A_MOUSE", "id": "Q5SP85-1", "name": "Coiled-coil domain-containing protein 85A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKAAGG---SAPAAESCPSAPAG--ASTPTGVDDLSKVTDEELLQWSKE------------------ELIRSLRRAEAEKVSAMLDHSN-------------LIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKELEVKQEEVVKENMELKELCMLLDEEKGVG----------CAGSRCSIDSQASLCQLVASATPYVRDVGDGSSTSSTGSTDSPDHHKHHAS-------GG---SPEHLQ----KPRSEG-----SPE-HTKHRSTSPEHLHKPRASGTPDHSKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPEVLPKHVLS-----GSPEHFQKHRPGGSPEHTRHSGGSPEHLQKHALGGSLEHLPRAR---GTSPEHLKQHYGASPDHKHASGSGGSGG---GSREGTLRRPAQEDSSSHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQ---------------------------------------------GSFRLSSGADGNNSSLNSPASFSGHTTPSQQPEPVVHSLK---------------------------------VVWRKLGDAAGSCPGIRQHLSGNQYKGPM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PX6-1", "uniprot_id": "CC85A_HUMAN", "id": "Q96PX6-1", "name": "Coiled-coil domain-containing protein 85A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKAAGGAAAAAAAAESCSPAPAGSSAAPPAPVEDLSKVSDEELLQWSKE------------------ELIRSLRRAEAEKVSAMLDHSN-------------LIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKGAG----------CAGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHAS-------SG---SPEHLQ----KPRSEG-----SPE-HSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLS-----GSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRAR---GTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIGRCLPTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQPEPVVHSLK---------------------------------VVWRKLGDAAGSCPGIRQHLSGNQYKGPM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AT27-1", "uniprot_id": "A0A8M3AT27_DANRE", "id": "A0A8M3AT27-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENSP-----QAQP---GSKAPES-------PAEDIANLTDEELLQWSKE------------------ELVQRLRRCEADKMSVILDHSN-------------LIREVNRSLQLHLNEIRGLKEVNQKLQDDNRELRDLCCFLDDDRQKGKRVSREWQRLGRFSASVMRKEVALYLQKLTELERKQEDVIRENLELRELCLLIDEDKGGGGVEGVQSGTGTIGCRNSIDSQSGL-----LVPGLMRDVGDGSSTSSAGSADSSSEHPHHKQPQPPSSTGTGNKSPDIQKSRSLKRGEGDHGEISSPDPPVRHRSTSLEYP-FVLPQPCRPRCGSISVPD---HRLIRGLSPEKYGRSLGHRSPETHPKHHLAPGQPMSPELYIQRHRG-----SLGSGPGSPE--PRHLLLGSAELHHEKSKLGGSSPEMLRHQYSMSPEHGKFGSPG---------RETSPRRLAGDELSPHHRSLYNGVNA-------------------------------------------------------------------------LISAGCCSNNCRN------------------------------------------------------------VKLWDRK----KIIQGWNKTEF----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8M3BEL9-1", "uniprot_id": "A0A8M3BEL9_DANRE", "id": "A0A8M3BEL9-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKPS-----QPQPHSGGSKSTEG-------PSEDLSKLTDEELLKWSKE------------------ELVRRLRRAEAEKMSVIVDHSN-------------LIREVNRRLQQHLNEIRGLKEVNQKLQEDNQELRDLCCFLDDDRQKGKKVSREWQRLGRYSAGIMRKEVTLYLQKLKELEQRQEEVVRENLELRELCLMLDEEKGSGGTSGSVGTGGPAGCRNSIDSQSSLSHASGPGPGLLRDVGDGSSTSSAGSTDSP-DHLTHKQQLLGGPVGG---SPDHLH----KPGSGE--EAPGPENPSRRHSTSQEYAAHTFPQVCRSRCGSFSSPD---HKGLRGLSPEKLAK---RGSPEQFSKHLLVSSQPPGSPDLFQKHRG-----SMGSVCGSPE--PKQILSGTPEHLQKGRVISGS-PELLRHQ------HVKFGSPG---------REVVQKRPGVEEMSPHHRSIYSGMNA-------------------------------------------------------------------------LISAGCCTSACRS------------------------------------------------------------VKLWDS----------FDTS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQK1-1", "uniprot_id": "Q9VQK1_DROME", "id": "Q9VQK1-1", "name": "", "aln": "MSGNQQQQQQQQKSLTNNAAAAATNEATTLGHNLIKINSVDKIVGKSQAATQAINKLQQQQQQQHQQQQIHQRRSLLPATGGATNPHQPHSSQQQSGTPTPTAQSAAQKQQQQQQQSHQLQTVATIHQPHSTQQQALTSRLPIQQQSTKELPNLAGQQRRSFHYQLQNQQQSLRSPQLKAPAPAHSIPPRYQPPPQPATGILKPHLPLKYPPDIPQLSSIYIPDSIKQQQQQQQQQQSRYLPAHQPGAKDMLKFVRKPDQEHPSPNASVTSSGTGIPTANGGGRLTAEQNRQLQSLVNELRALKEQNQRLLDDNQELRDLCCFLDDDRQKGRKLAREWQRFGRYTASVMRQEVAAYQNKLRQLDDKQQELITDNLELKELCLYLDEE------------------RAHVAANALCAGCGAATRNALRDDGDGSSSSTNADETITALRNYAEQRQ----------LPQDLR----HAHTLN--------DQTLQYVRSLERRIQQLEEERTTPTAHLQQPT----TPTPQATPTPTVTSAATPAKSAASPHQQQ--------QQQQQHQQQQQDIVAAAAAAAAAIQLPEPIAGRPEAVVRALQVLEVREQLERDRLGNLAGSALDQMDDGEKA---LVREMCNVVWRKLEGSPHGPAALEPL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . :::.: : :: .:: :::: :*: : :: * . :. * * ** ** :.*:*.**: **:* :**:****************::::*****:**::*.:*::**: * :** :*: :*:::: :*:**:***: :**: * : ::: :** *****:*: .. . : . *: : : : * * :. * :* : . . * *:*: .:. . : * * . : :.: . ** : *.* . : ", "identical_positions": 80, "similar_positions": 99, "identity": "9.57%" }, { "cls_id": "homologset.agr.MGI:2445077", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BZT9-1", "uniprot_id": "LACC1_MOUSE", "id": "Q8BZT9-1", "name": "Purine nucleoside phosphorylase LACC1", "aln": "MAEAVLIDLSGLQLNAQKNCHETLLETLDGIHYHHAPKAKFLCIICCRNASKEKDGEYGLCELEAGNGFSRLAGKFETVSHPCLAASLYTIKQKIDEENLSCIKVIVPEHRKLLMKAYVGQLFTEVYEFEFEDLQGAWRDSLLKPSTGINVTTTQELEDIQHEIETYLRSLPALKGDLTIVTSPLIPDNFLHGFTTRTGGISSVPTLSSLNLFSSSKRRDPKVVVQENVRRLANAAGFNAEKFYRIKTDHASEVWVMGKKEPESYDGIVTNQRGVTITALGADCIPIVFADPVKKACGVAHSGWKGTLLGVAMATVNAMIAEYGCDVEDIIVVLGPSVGSCCFTLPKESAVSFHSLHPSCVRHFDSPRPYVDIRKATRILLERGGILPQNIQ----DQKEDLDLCTSCHPEKFFSHVRDGLN------------FGTQIG----------FISLRE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LVZ9-1", "uniprot_id": "A0ABK0LVZ9_RAT", "id": "A0ABK0LVZ9-1", "name": "Purine nucleoside phosphorylase LACC1", "aln": "MAEAVLIDLSGLQLNSQENCHQMVLKTLDGIHDHHAPKAKFLCIICCSDATNGKGGEYGLCELEAGNGFSSLAGKFETVSHPSLAASLYSVKQKIDEEDLSRVKVIVPEHRRLLMEAYVDQLFTAVYEFEFEDLQVAQRESLLKPSTGVNVTTAHKLEDVQSEIESYLRSLPALKGDLTIVTSPLIPDIFLHGFTTRTGGISYIPTLSSLNLFSSSKRRDPKVVVQENLRRLANAAGFNAEKFYRIKTDHASEVWVMGKKEPESYDGIITNQRGITITALGADCIPIVFADPVKKACGAAHSGWKGTLLGVAMATVNAMIAEYGCNLEDIIVVLGPSVGSCCFTLPRESATSFHNVHPSCVRQFDSPNPYVDIRKATRILLERGGILPQNIQ----DQEEDLDLCTSCHPEKFFSHVRDGLNFVWPPFPSALAHFPTPVLSALWLLPNGEFFSFHAVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IV20-1", "uniprot_id": "LACC1_HUMAN", "id": "Q8IV20-1", "name": "Purine nucleoside phosphorylase LACC1", "aln": "MAEAVLIDLFGLKLNSQKNCHQTLLKTLNAVQYHHAAKAKFLCIMCCSNISYERDGEQDNCEIETSNGLSALLEEFEIVSCPSMAATLYTIKQKIDEKNLSSIKVIVPRHRKTLMKAFIDQLFTDVYNFEFEDLQVTFRGGLFKQSIEINVITAQELRGIQNEIETFLRSLPALRGKLTIITSSLIPDIFIHGFTTRTGGISYIPTLSSFNLFSSSKRRDPKVVVQENLRRLANAAGFNVEKFYRIKTHHSNDIWIMGRKEPDSYDGITTNQRGVTIAALGADCIPIVFADPVKKACGVAHAGWKGTLLGVAMATVNAMIAEYGCSLEDIVVVLGPSVGPCCFTLPRESAEAFHNLHPACVQLFDSPNPCIDIRKATRILLEQGGILPQNIQ----DQNQDLNLCTSCHPDKFFSHVRDGLN------------FGTQIG----------FISIKE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1REB6-1", "uniprot_id": "F1REB6_DANRE", "id": "F1REB6-1", "name": "Purine nucleoside phosphorylase LACC1", "aln": "MAAVTLVDLTNICSSESDICVKNRIRTFCAVTENGSQEPVYFVADPGSSFGTIRFPRSSLLEMFVG-----FSNSPQILCKSSLSASLYSFKQAIDESDISNVRIVTSSRGRGVFQVYQELLFTSAYSFEYCIMFDNLSCDSCPPGDRANSSTPAEG-DARLELSAFLQRLPAVKGDITVLRSAAISDCFGHGFSTRTGGISYISTMSSMNLFCNPRRKDPRAVVDENRRRLGLQAGFHSRQLNLIKCNHASDVWVMGKPAPDSYDGLVTNQSDVVIAAPGADCMPLLFTDPVSKVIGVAHAGWKGTLMGIAMATVKAMVSEFGSRPADIVVVIGPSVGPCCFTLEQDSAREFHSIHPDCVQNMESSEPSVDIRVATRVLLERGGIKPEHIENIRIPNQTDSIPCTSCSPELFFSHRRDGLN------------FGTQIG----------FLWIKP--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ..*:** .: . .. * : :.*: .: : : :. :: . : . . *: .. : . : :. ..::*:**:.** ***.::* ::::.. : : :::.: *** .*.**: : . . * *. : . : *:.::*: ***::*.:*:: *. *.* * ***:******* :.*:**:***...:*:**:.**:** ***. ***: .:: ** .*:.::*:**: *:****: *** .:.*:* ****:*::*:***.*. *.**:******:*:*****:**::*:*. **:**:*****.***** ::** **.:** **: ::*..* :*** ***:***:*** *::*: :: * **** *: **** ***** * * : *: :: ", "identical_positions": 166, "similar_positions": 149, "identity": "36.24%" }, { "cls_id": "homologset.agr.MGI:2445082", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BU25-1", "uniprot_id": "PAMR1_MOUSE", "id": "Q8BU25-1", "name": "Inactive serine protease PAMR1", "aln": "----------------------------------------------------------------------------------------------MELDRWAQLGLVFLQLLLI------SSLPREYTVINEACPGAEWNIMCRECCEYDQIECLCPGKKEVVGYTIPCCRNEDNECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRASKGQILLESYPLNAHCEWTIHARPGFIIQLRFGMLSLEFDYMCQYDYVEVRDGDNSDSPIIKRFCGNERPAPIRSTGSSLHVLFHSDGSKNFDGFHAVFEEITACSSSPCFHDG-TCLLDTTGSFKCACLAGYTGQRCENLLEER--------------------------------------------------------NCSDLGGPVNG-----------------------------------------------------------------------------------------------YKKITEGPG-----------------------------------------------------------------------------------------------------------LLNERHVKIG-------------------------------------------------------------------------------------------------------------TVVSFFCNGSYVLSGNEKRTCQQNGEWSGKQPVCMKACREPKISDLVRRRVLSMQVQSRETPLHQLYSTAFSKQKLQDASTKKPALPFGDLPPGYQHLHTQVQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIESTPSPKTQGTRWPWQAAIYRRTSG---VHDG----------------------GLHKGAWFLVCSGALVNERTVVVAAHCVTELGKATIIKTADLKVVLGKFYRDDDRDEKSIQNLRVSAIILHPNYDPILLDTDIAVLKLLDKARISTRVQPICLATTRDLSTSFQESHITVAGWNILADVRSPGFKNDTLHYGMVRVVDPMLCEEQHEDHGIPVSVTDNMFCASKDPSTPSDICTAETGGIAA----------------LSFPGRASPEPRWHLVGLVSWSYDK-TCSNGLSTAFTKVLPFKDWIERNMK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0L414-1", "uniprot_id": "A0ABK0L414_RAT", "id": "A0ABK0L414-1", "name": "Inactive serine protease PAMR1", "aln": "MNIVPSLILAVPEPFLLPFPARYCPPHISTFTITKGWSRKSSEREQALVFRCFPVSRGASARASQGLRGELWADVVALAEGATPVTPGSAAVGTMELDRWAQLGLAFLQLLLI------SSLPREYTVINEACPGAEWNIMCRECCEYDQIECICPGKKEVVGYTIPCCRNEDNECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRASKGQILLESYPLNAHCEWTIHARPGFIIQLRFSMLSLEFDYMCQYDYVEVRDGDNSDSPLIKRLCGNERPAPIRSTGSSLHVLFHSDGSKNFDGFHAAFEEITACSSSPCFHDG-TCILDTTGSFKCACLAGYTGPRCENLLEER--------------------------------------------------------NCSDLGGPVNG-----------------------------------------------------------------------------------------------YKKITGGPG-----------------------------------------------------------------------------------------------------------LLNERHVKIG-------------------------------------------------------------------------------------------------------------TVVSFFCNGSYVLSGNEKRTCQQNGEWSGKQPVCMKACREPKISDLVRRRVLSMQVQSRETPLHQLYSTAFSKQKLQDASTKKPALPFGDLPPGYQHLHTQVQYECISPFYHRLGSSRRTCLRTGKWSGRAPSCIPICGKIESVASPKTQGTRWPWQAAIYRRTSG---VHDG----------------------GLHKGAWFLVCSGALVNERTVVVAAHCVTELGKVTIIKTADLKVVLGKFYRDDDRDEKTIQNLRISAIILHPNYDPILLDTDIAVLKLLDKARISTRVQPICLATTRDLSASFEESHITVAGWNILADVRSPGFKNDTLHYGMVKVVDSMLCEEQHEDHGIPVSVTDNMFCANKDPSTPSNICTAETGGIAA----------------LSFPGRASSEPRWHLVGLVSWSYDK-TCSNSLSTAFTKVLPFKDWIERNMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UXH9-1", "uniprot_id": "PAMR1_HUMAN", "id": "Q6UXH9-1", "name": "Inactive serine protease PAMR1", "aln": "----------------------------------------------------------------------------------------------MELGCWTQLGLTFLQLLLI------SSLPREYTVINEACPGAEWNIMCRECCEYDQIECVCPGKREVVGYTIPCCRNEENECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRAPKGQILLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSPCFHDG-TCVLDKAGSYKCACLAGYTGQRCENLLEER--------------------------------------------------------NCSDPGGPVNG-----------------------------------------------------------------------------------------------YQKITGGPG-----------------------------------------------------------------------------------------------------------LINGRHAKIG-------------------------------------------------------------------------------------------------------------TVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICIKACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTKKPALPFGDLPMGYQHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIENITAPKTQGLRWPWQAAIYRRTSG---VHDG----------------------SLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICLAASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVSVTDNMFCASWEPTAPSDICTAETGGIAA----------------VSFPGRASPEPRWHLMGLVSWSYDK-TCSHRLSTAFTKVLPFKDWIERNMK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QE83-1", "uniprot_id": "F1QE83_DANRE", "id": "F1QE83-1", "name": "Inactive serine protease PAMR1", "aln": "-----------------------------------------------------------------------------------------MSSSVCLHSSHSSICLSFIIIIIITLLEHCSAWPYDYRFVPSWCPGPEWSVLCRGCCEYDVIRCKCPLQGAPVGYAVPCCRNAADECDPCTIHPGCSIFENCKRCNNGTWA-PRDDFFLKGQYCAECRPGWSGGDCMTCGGLIHKRQGHLVLESYPNNARCEWTLRVDRPYTIDLRFMMLSLEFDHSCQYDYVEVRDGDSLNSRLIGRYCGNERPPPIRSSGSSLHLLFVSDGYKHFDGLFAIFQESSECISSPCLHDG-TCVVDSSRSYHCACLAGYTGKRCEHVLECRRPLIPAHGSMRHLDERVGGHVVFQCEPGHTLKGFRISTCLLDGSWSSPTPQCVPFQNCGIPPKPENGDHFLVYGPNDVLIAIQYFCYKQYKLKGAPQRTCLGNNTWSGTAPTCITEPDVIPTADHEQDKGKVKPSGADDVGDAKNKTSQEEENESKPDKDIKAQKPTAGKGYDLVLGKDVEKEIVSIFVKEKPKAEYKESDSSINTIEKKDPGEDKDTLKVLGKDEHLHIEEKVVTPSRDVELVDIVLIDNQMENKTTDDNTGREYTISRLNEDRKENLLNEVDVTQQENNTGFFDSNDIDENADTPRLKQTEEPPSPTAVHYSTETTTTASRSTARAAVKPALQEDPQHVETADVQQEPTAESPPTAQNEAGEVTPCPPPPPLYHGFSERVSGVRPETLRFFCNQSYALVGSDRRTCQADGSWSGAQPVCIRACREPKVSVLVRQKVLPPHVPSRKTPVHKFYSSSVSTVFLKDVRATQSPLSLPTLPQGFHHLYTHIEYECASQYYQHSGSSRRTCLKMGKWSGRHVSCSPVCGKLSSFDPQKPEQTQWPWLASIYRRPAGKLKLKSGK----------------EDQAEDQAEDGWQLVCSGALVNQRSVVVAAHCVTELGKTHPLDPHTLRVTLGKHYRSERRHTKGLQTVRVSSIALHPTFDPLVLDSDVAVLKLLDKARIGEHVVPVCLPDP-----QLTADQGLVTGWSLEPDP--ADADGERARVGHVLMGDTVQCEQQYASHGLPISVSENMLCG--RQAERSNICPADTGGIL-----------------LSPAGSAHTPQHWTLLGLVSFGFESSVCSSELYTVYTHIANFVSFIEANMT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0AB32TXW9-1", "uniprot_id": "A0AB32TXW9_DANRE", "id": "A0AB32TXW9-1", "name": "", "aln": "---------------------------------------------------------------MHMSRRKLSVSRCLNLSGQLAVSAGIWMAPESGYHSASLLVLLYLLQLLSTG----ASWPNVFRSQEDKCPGPQWNAMCRTCCEYEQIACKCPSQGVKVGYAVPCCRNVLDECDPCILHQGCSIFDNCKTCSNGTWQ-AKDDFYIRGRYCTSCRQGWSGGDCLTCGEVIQRPHGHVTLESYPINAKCEWTLKVGRGTTMELRFSMISLESDHSCQYDYVEVRDGDSLKSPVIGRYCGDESPGPIKSSGNSLHIRFVSDGYNNYDGFFATFQEVSGQAPALCATPKKPANGDLFLRYNEGGLLHSAQYLCYKPYQLKG----------------------------------------------------ASQRACLPNGTWSG----------------------------------------------------------------------------------------TAPVCIKEVAIKDCPAP--------------------------------------------------------------------------------------------------------PQLHNGYSTEISASNG-------------------------------------------------------------------------------------------------------RLKYVEYSCNNTYILSGDWRRVCQKNGSWSGSQPMCVRACREPKVSKLVRQKLLKYQPPSRKSPVHKLYSAS-SQGATEGDSRERAFPAFGDLPPTFHHVYTSIEYECVSALYKPSGSGRRTCLKTGKWSGRHFSCSPACGKLPPASPLNLTEIYWPWHAAIYTRLYNASPLVARTKRRGDTFAVDEEAEEKEEEDGHKKAQKWQLVCSGALVTQHWVVVAAHCVAKTGQTEALGADHLNIVMGKHHLSDPKDNKRLQHIQIAQILIHPNYDPHVLDSDVALLKLADKARISEYISPVCLPRLQ--GGEVTATQAFLSGWPI-ADQHGLMTDSEAARTGQIELADVVKCESQFGKHGLAVSMTDNMLCGRQHPLSSSMICPSETGGIVLSPSDESKITSNSQVIDSSKADDADSHHSWELLGLVSFGYDLQGCNPDLYTVYTRVGNFKNWIERNIT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :: :: :: * : . ***.:*. :** ****: * * ** : ***::***** :***.* :* **:**:*** * **:* . ***:::* **:.** ** ****: ** ::: :*:: ***** **:****::. ::*** *:*** *: ************. .. :* * **:* * **:* *.***: * *** :::**:.* ::* : .: * .. * :: . * : * : : : .. . .* . . * * . : : ** :* * *. :*.** :*.*** **:*::******:* ***:::* : **::*:*::**:: * :. :. .: ** ::*::* ::*** * *: **.*****: ****** ** * ***: . : *** *:** * . : * ********.:: ********:. *:. : . *.:.:**.: .: :. * :* :::: * :**.:** :**:*:*:*** *****. : *:**. .. : ::** : .* ..: : * : : * : **.*. .**:.:*:::**:*. * **.::**** * .. * . * *:****:.:: *. * *.:*:: * .:** *:.", "identical_positions": 264, "similar_positions": 203, "identity": "21.46%" }, { "cls_id": "homologset.agr.MGI:2445085", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5YCM7-1", "uniprot_id": "A0A8I5YCM7_RAT", "id": "A0A8I5YCM7-1", "name": "Cytoplasmic dynein 2 intermediate chain 1", "aln": "MEPGKRRTKDDTWKADDLRRHLKAAQSGSPKEEKKLREKKMHKDSELGTPEYREHKSRDPDREARHKEKTVERDLYSSTEHPRGERDRERHKERRKDGKDREKDKLKERHRDQEAEKSHSRGKDREREKDRRVRKEELRQSMAYHDLLGRD-VRGRQMLEKVEKKVHIASKLRMEERERRDEDSERVDEDRERRYRERKLQYGDSKENPLNYWLYKEDGEKKHRKVKDADRERKHREKSSTREKKDRHSKEK----GSSLSDREIEDRHREKRHKDGLH---------YDEERRRSHADKKERSLKEEHRKRESK------------------------------------------------------------EPEKEDNGLEATGADEYLPNLEDDFVDYEDDFEVCDGDDD-SNNEHE-------AKEKADELPLAQKREIQEIQKAISAENERVGELSLKMFQKQGRAENTKEPWADANDSTSRTPVCGIFVDFATASHRQKSRSQALKQKTRSTKLLRLIDLDFSFTFSLLDLPPVNEYDMYIRNFGKKNTKQAYVQYNEDNVERDIQTEDIETREVWTQHPGEGTVVSGGSE--EKDFSDVTVVPKIDTPRLSNFLRAACQVVAVLLEEDRLAAGPSWIPRAQDKALNISDSSSQLNTSLPFLQSRKVSCLHASRVQRQTVVSVHDLPEKAFAPSLDSRHLLCVWDIWQPSGPQKVLICESKVTCCCFSPLKAFLLFAGTVHGSVVVWDLREDSRIHHYVRLSSCFWAFRTPTFSTDGILTSVNHRSPLQAIEPVATSAYKKQSFVLSPFSTQEEMAGLSFHIASLDESGVLNVWVVVELPKADISGSMSD----------------LGLIPGGRIKLVHSTVIQLGHSLSHKDGELWGSTQTLSVKFLPSDPNHFVVGTDMGLISHSTRQDWRVSPKVFKPQQHGVRPIKVNVIDFSPFEETVFLAGCSDGSIRLHQLTSERPIMQWDNSTSGRSVTSLQWSPTRPAVFLVQDDASRIYVWDLLENDLGPVAQQPISPDKLVAMTIVGEPEKTSGSFVALVLARTSGTVDIQNLKRRWTTPAADEHSQLHLLLQK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C761-1", "uniprot_id": "DC2I1_MOUSE", "id": "Q8C761-1", "name": "Cytoplasmic dynein 2 intermediate chain 1", "aln": "MEPGKRRTKDDTWKADDLRKHLKVQ-SGSPKEEKKLREKKAHKDSESAAPEYREHKSRDPDREARHKEKTAERDLYTSTEHPRGERDRERHKERRKDAKDREKDKLKERHRDQEAEKAHSRGKDREREKDRRARKEEIRQSMAYHDLLSRD-MRGRQMAEKVEKK---ASKIRTEERERRDEDSERIDEDRERRYRERKLQYGDSKEHPLSYWLYKEDGEKKHRKAKDADREKRLREKSSMREKRERHAREK----GSSLSDREVEDRHREKRHKEGLH---------YDDERRRSHADKKERSSKEEHKKRELK------------------------------------------------------------ELEKEDNDLEATGPDEYLPNLEDDFVDYEDDFEVCDGDDD-SNNEHE-------AREKAEELPLAQKREIQEIQKAISAENERVGELSLKMFQKQGWTEYTKEPWTDANDSPSRTPVCGIFVDFATASHRQKSRSQALKQKTRSSKLLRLIDLDFSFTFSLLDLPPVNEYDMYIRNFGKKNTKQAYVQYNEDNVERDIQTEDIETREVWTQHPGEGTAVSGGSE--EKDFSDVTVVPKIDTPRLANFLRAACQVVAVLLEEDRLAAGPSWIPRAQDKALNISDSSSQLNTSLPFLQSRKVSCLHASRVQRQTVVSVHDLPEKAFAPSLDSRHLLCVWDIWQPSGPQKVLICESKVTCCCFSPLKAFLLFAGTVHGSVVVWDLREDSRIHHYVRLSNCFWAFRTPTFSTDGILTSVNHRSPLQAIEPVATSAYKKQSFVLSPFSTQEEMAGLSFHIASLDETGVLNVWVVVELPKADISGSMSD----------------LGLIPGGRIKLVHSTVIQLGNSLSHKDSELWGSTQTLSVKFLPSDPNHFVVGTDMGLISHSTRQDWRVSPRVFKPEQHGVRPIKVNVIDFSPFEETVFLAGCSDGSIRLHQLTSERPIMQWDNSTSGHAVTSLQWSPTRPAVFLVQDDASRIYVWDLLENDLGPVAQQPISPDKLVAMTIVGEPEKTSGSFVALVLARTSGTVDVQNLKRRWTTPAVDEHSQLRLLLQK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVS4-1", "uniprot_id": "DC2I1_HUMAN", "id": "Q8WVS4-1", "name": "Cytoplasmic dynein 2 intermediate chain 1", "aln": "MEPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAE--VHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHR--EAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQE-TRDRQLLERAERKGRSVSKVRSEEK---DEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEK----SNSFSDK-GEERHKEKRHKEGFH---------FDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPE-------SREKLEELPLAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEFEKEPRTDTNSSPSRASVCGIFVDFASASHRQKSRTQALKQKMRSTKLLRLIDLDFSFTFSLLDLPPVNEYDMYIRNFGKKNTKQAYVQCNEDNVERDIQTEEIETREVWTQHPGESTVVSGGSE--QRDTSDAVVMPKIDTPRLCSFLRAACQVMAVLLEEDRLAAEPSWNLRAQDRALYFSDSSSQLNTSLPFLQNRKVSSLHTSRVQRQMVVSVHDLPEKSFVPLLDSKYVLCVWDIWQPSGPQKVLICESQVTCCCLSPLKAFLLFAGTAHGSVVVWDLREDSRLHYSVTLSDGFWTFRTATFSTDGILTSVNHRSPLQAVEPISTSVHKKQSFVLSPFSTQEEMSGLSFHIASLDESGVLNVWVVVELPKADIAGSISD----------------LGLMPGGRVKLVHSALIQLGDSLSHKGNEFWGTTQTLNVKFLPSDPNHFIIGTDMGLISHGTRQDLRVAPKLFKPQQHGIRPVKVNVIDFSPFGEPIFLAGCSDGSIRLHQLSSAFPLLQWDSSTDSHAVTGLQWSPTRPAVFLVQDDTSNIYIWDLLQSDLGPVAKQQVSPNRLVAMAAVGEPEKAGGSFLALVLARASGSIDIQHLKRRWAAPEVDECNRLRLLLQEALWPEGKLHK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G5F0-1", "uniprot_id": "A0AC58G5F0_DANRE", "id": "A0AC58G5F0-1", "name": "", "aln": "MRSVKKITKEDTWRSDDLKVHIQAHNEESRRRSKRVEEHRKHRDG-----ESEDRRHRDPDRDPRREKEKRREREGSKHRDPERDRNQDIKREDVREDRHKERRREREKARHGDGDEDEKRYNRDDKENGERRRDREKDRNVDMYNQEDKERERDRRRAERARRK---------EERGEGEKEERERDKERERERRERHRAR-ESDRYRLEYDEKQREGERRERHSDKEHSGHKEREHRRDREDKERRRRDKESHMAKTSHSREAEHHRQELKDSKDFHGIKDGESEKAREERERRHERKHKEASDSKRSDREQK---------------------QDLSGHDLNARISRDKEETTKRPQLTWRSDQAETSDPEVSVENEETEQDKESSKDDRNHYEEDFEDYEEDFEDVDEDEDDKAEEDEKEEHENKAREDKRELSPRRRQEIEAIQRAMDEENE-------RIYSARSKPSTADSTVTQRDRLSNANQTRGTIIDFVSAKQREISQKVARKQKKRSEELLRLIDLDFSITFSMLDLPPVNEYDMYIKNFGTANTKQAYVQCNEDSTDRDIQTEDVEMTDKWTQHPPEAKSACGGSTGTQANAVESIARTSTDSKRLTTFLRSAAQVMAVLVEENMAQSNSVKKLCSKTDALSFSDGCIQLNTKLPFLNGRQVSLLQFSQVQRQTLLSVHPPSSKNSSVRLDSETVVCVWNIWEPSRPQKILLYESEVKCCCFSPGKVTLVFAGTAVGSVIVWDLREHSGSHSNLEIGKEVWTLRYPTFSTDAVLSGVGHLSPVVSIEPVIASADMSSTSTLT--ADIEECMGLSFQLGSLDENGVLTLWVVIELPKGNDSGSQTDLVPLDLHHASNAVSILLGLRPGGKVKLLHSSSLQTTERLPKDTIMGFGPSVSLQLKFLPSDSNHYFIGTNMGLVRHGTRHSLKVLPKVYRSQSDSYRPVEVTALDFSPLGEPFFLIGCSDGSVRLHSVLREDPLMEWAGRSSGAPILSVQWSQTRPAVFCVLDAASDLHIWDLTEKDYVPVITENIHSDRVTAMAVFGEPAKQN-TFSGIALAKQSGKVEIQYFKKSLTVSSASDKEKIDSILHDAFLTRDMR--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. *: **:***::***: *: . . . :..:: .*:: :::. * .: : ****::.* ... . : . *. :*::: ::* :: :.:*: : :*: * :.:: ..* : ::*:..* *..* :.: :: .:: *.*: *:..:* **: :::... *::***. ***: :*. *.* :.:**::.*: . . .: **: **.::: ::* ..: .: *.:::* :....:* :**.: : :::.: ..: .** : . *:*:. : .. *:** ***:*** * *:* . :* * ::*. **. :::**: **:*:. *** :::. :. .. ... :: : .. . * ::**.:*.:*: *:. * *** ** :**********:***:*************:***. ******** ***..:******::* : ***** *.. ..*** : : : . .. *: ** .***:*.**:***:**: : . :: ** :**.. ****.****:.*:** *: *:**** ::*** ..* ***. ::***:**:** ***:*: **:*.***:** *. *:****. ***:******.* * : :.. .*::* .*****.:*:.*.* **: ::**: :*. ..: .*: : ** ****::.****.***.:***:****.: :** :* *** ***::**:**: :* . *.:. :*.: :*.:******.**:.:**:***: *.**:. :* *::::.:... **::*..:****: *..** ******:***.: *:::* . :.. .: .:*** ****** * * :* :::*** :.* ** : : .:::.**: .*** * . :* .:.**: **.:::* :*: :.. ..: .:: :*:. ", "identical_positions": 357, "similar_positions": 380, "identity": "32.08%" }, { "cls_id": "homologset.agr.MGI:2445087", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0C3-1", "uniprot_id": "HID1_RAT", "id": "D4A0C3-1", "name": "Protein HID1", "aln": "MGSADSK---------------------------------------LNFRKAVIQLTT--------KTQPVEATDNAFWDQFWADTATSVQDVFALVPAAEIRAVRE-ESPSNLATLCYKAVEKLVQGAEGG--CHSEKEKQVVLNCSRLLTRVLPYIFE-----DPDWRGFFWSTVPGAGRGGQGEEEDENARPLAESLLLAIADLLFCPDFTVQNHRR-------NDVDSAEDVHSLDSCEYIWEAGVG------FAHSPQPNYIHDMNRMELLKLLLTCFSEAMYL----------------------------------------------------------PPSPESGSTNPWVQFFCSTENRHALPLFTSLLNTVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDHDSATSTSPTVDGTTTGTVMDDADPP----------GPENLFVNYLSRIHREEDFQFILKGIARLLSN-----PLLQTYLPNSTKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILYFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSVRVPMDIPVFTGTHAD----------------------LLIVVFHKIITSGHQRLQPLFDCLLTIVVNVSPYLKSLSMVTANKLLHLLEAFSTTWFLFSASQN--------------------------HHLVFFLLEVFNNIIQYQFDGNSNLVYAIIRKRGVFHQLANLP---TDPPSIHKALQRR-------------RRTP----------------------------------------EPLSRAGSQEGASMEGSRPAAPAEPGTLKTSLVATPG----------------------------------------------------------------------IDKLTEKSQVSEDG---TLRSLEPESQQNSAEGSPSEGEPNQTWREQRRLSNAS---------ASGQWS---PTSDWILSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILRFLQHGTLVGLLPVPHP----------------------------------------------ILIRKYQANSG------------------------------TAMWFRTYMWG-------------------------------VIYLRNVDP---------PIWYDTDVKLFEIQRV------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1F6-1", "uniprot_id": "HID1_MOUSE", "id": "Q8R1F6-1", "name": "Protein HID1", "aln": "MGSADSK---------------------------------------LNFRKAVIQLTT--------KTQPVEATDNAFWDQFWADTATSVQDVFALVPAAEIRAVRE-ESPSNLATLCYKAVEKLVQGAEGG--CHSEKEKQVVLNCSRLLTRVLPYIFE-----DPDWRGFFWSTVPGAGRGGQGEEEDENARPLAESLLLAIADLLFCPDFTVQNHRR-------NDVDSAEDVHSLDSCEYIWEAGVG------FAHSPQPNYIHDMNRMELLKLLLTCFSEAMYL----------------------------------------------------------PPSPESGSTNPWVQFFCSTENRHALPLFTSLLNTVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDHDSATSTSPTVDGTTTGTAMDDADPP----------GPENLFVNYLSRIHREEDFQFILKGIARLLSN-----PLLQTYLPNSTKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILYFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSVRVPMDIPVFTGTHAD----------------------LLIVVFHKIITSGHQRLQPLFDCLLTIVVNVSPYLKSLSMVTANKLLHLLEAFSTTWFLFSASQN--------------------------HHLVFFLLEVFNNIIQYQFDGNSNLVYAIIRKRAVFHQLANLP---TDPPSIHKALQRR-------------RRTP----------------------------------------EPLSRTGSQEGTSMEGSRPAAPAEPGTLKTSLVATPG----------------------------------------------------------------------IDKLTEKSQVSEDG---TLRSLEPESQQSSAENSPSDGESSQTWREQRRLSNAS---------ASGQWS---PTSDWILSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILRFLQHGTLVGLLPVPHP----------------------------------------------ILIRKYQANSG------------------------------TAMWFRTYMWG-------------------------------VIYLRNVDP---------PIWYDTDVKLFEIQRV------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IV36-1", "uniprot_id": "HID1_HUMAN", "id": "Q8IV36-1", "name": "Protein HID1", "aln": "MGSTDSK---------------------------------------LNFRKAVIQLTT--------KTQPVEATDDAFWDQFWADTATSVQDVFALVPAAEIRAVRE-ESPSNLATLCYKAVEKLVQGAESG--CHSEKEKQIVLNCSRLLTRVLPYIFE-----DPDWRGFFWSTVPGAGRGGQGEEDDEHARPLAESLLLAIADLLFCPDFTVQSHRR-------STVDSAEDVHSLDSCEYIWEAGVG------FAHSPQPNYIHDMNRMELLKLLLTCFSEAMYL----------------------------------------------------------PPAPESGSTNPWVQFFCSTENRHALPLFTSLLNTVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDHDSASSASPTVDGTTTGTAMDDADPP----------GPENLFVNYLSRIHREEDFQFILKGIARLLSN-----PLLQTYLPNSTKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILFFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSIRVPMDIPVFTGTHAD----------------------LLIVVFHKIITSGHQRLQPLFDCLLTIVVNVSPYLKSLSMVTANKLLHLLEAFSTTWFLFSAAQN--------------------------HHLVFFLLEVFNNIIQYQFDGNSNLVYAIIRKRSIFHQLANLP---TDPPTIHKALQRR-------------RRTP----------------------------------------EPLSRTGSQEGTSMEGSRPAAPAEPGTLKTSLVATPG----------------------------------------------------------------------IDKLTEKSQVSEDG---TLRSLEPEPQQSLEDGSPAKGEPSQAWREQRRPSTSS---------ASGQWS---PTPEWVLSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILRFLQHGTLVGLLPVPHP----------------------------------------------ILIRKYQANSG------------------------------TAMWFRTYMWG-------------------------------VIYLRNVDP---------PVWYDTDVKLFEIQRV------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E9B5-1", "uniprot_id": "Q0E9B5_DROME", "id": "Q0E9B5-1", "name": "Protein HID1", "aln": "MGNTDSK---------------------------------------LNFRKAIVQLTQ--------KNQKIDPSDEQFWEQFWQGHQTTLEDVFALVTSSEIRQIRN-ENPANLATLCYKAVEKLAQAVDSS--CRTQAEQQCVLNCVRLLVRCLPYIFE-----DEKWRDFFWSSLP----------SQDKTMPLAQSLLNATCDLLFCPDFTVTATRR-------AGPEKAEELANIDSCEYIWEAGVG------FAQSPPHNAHMERRRTELLKLLLTCFSEPMYR----------------------------------------------------------SPQ-QSEEPNKWIAYFTSADNRHALPLFTSFLNTVCSYDPVGFGVPYNHLLFADTTEPLVEACLQLLIVTLDHDMVVQQQLTQPGQAS---YDEGN------------CGDNLFINYLSRVHRDEDFHFVLKGITRLLNN-----PLVQNYLPNSTKRLHCHQELLILFWKICDYNKKFLYFVLKSSDVLDILIPILYHLNYSRADQSRVGLMHIGVFILLLLSGERNFGVRLNKAYSATVPMDIPVFTGTHAD----------------------LLITVFHKIIATGHQRLQPLFDCLLTILVNVSPYLKTLSMVASVKMLHLLEAFSTPWFLLSAPSN--------------------------HHLVFFLLEIFNNIIQYQFDGNSNLVYTIIRKRHVFHAMANLP---TDMAGIAKCLSGRKTGGKFNLPRVPQRRTPAVSQELPSAHVPEEYNEEDEDEDEEEIINEEPKAEEDLESETESHERSQAGELQSDVLTAQPAEPGTLKTSLLDTPG----------------------------------------------------------------------ITQMTEREQAHPNDKPQVEDSTDIVPYDRSAASTPTDERKSTSPTELSRLSVAHRASIRMVPGESDRWT---PTPEWIVSWRSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILKFLQHGTLVGLLPVPHP----------------------------------------------ILIRKYQANAG------------------------------TTAWFRTYIWG-------------------------------VIYLRNVEP---------AIWYDTEVKLFEIQRV------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06673-1", "uniprot_id": "HID1_YEAST", "id": "Q06673-1", "name": "Protein ECM30", "aln": "MGNTDSKSSSILLNHCIALVRPEDADASSPSRTSSPSPSLSVDADPLSLNLSIFKLDSGPDVEALFSDKPNVPLDTVFNDFYLDFISVDVQDFSINSSFKKILHIISSLNPPNFNNLIVFLSLYIILSANSLPASRTGLHSSRLINAIKTLSILIPIYFDRVKSSTQDHYDVFWATQHEIEG------LPLQNIPLGERLLLAILKLAFQDNFTTAVTAHPSELWEIGILTNSNKYRSLLNMHHQWHLFANRLLLLRLLAALFSSDLYTSGGKQDINMFLVYWCTQMPKDKSIQFTSSLLNCTMRFILNNNKDFQSLKANFFSSDATASNWQTLYFQFVQSCLHVLNLSMSYKAQDNVITIFLTQLQREYDLKLILSSFIKIFKY-PIDLAIEQESNIFNFTNNKHIDASRRRAVSTSSHDNSSSSHASLPSSSSAAYHTKPQTKPQLPEIHPLLIPMTILMTNLIDCNKCFQNYFADKFASRFIIFSIYYLKYYDYSSLSSSSSTTRSNSSTTSNGTSNDTSNERSIVELNENSVSQILLPLLNHLLLILTSKKLVLFKMLQTFNLNYYTNNLPNFYKLSNINGDINNLTFRDFTVIQLSNLILDNIKFNLQPNPIFYELIYNLLPINDEILTSSHKNDDSHDDLILLSAKKKSASPSAATSSHTSSSKLSYNAAMSLLYVLSKSSNKVYLTTYATPVFKTKDIPYMISPGFKMDLLALLLRSITIFFTLYFDDAENLLFAMVRHQSITHQINDSINSISKALDMNPNLNSHIMTLKQMGFNRKVQWKDFYQFEEITDLPQVNLYSSANQQHQNQQQGQNDNRGQNQNEDPGQENESPTPYLLFNPASLENETPGTVKHFSSTNHDKNYQVIAFIDFKSDSNLNLQHQLEYWPHRPQWPTPLTFTHKCKNPKYENFNEVWSGTVYLQILLRVIKQILSKVPEIPRIKSVQYFETLSKLSALRSDILTTIHPRLPLDVRRLTTFQPLSMHTN-DKLLMWFHIATWANIFTQTSFKYEETFSHELRQFESLLDISIDECEGNTISKPTTDRLGYIRRSRGQSSVSLERTISAGSGVSTPTMALNRTKSNGSGNLMNYFFQNTAQNHFQHLRSSSSSSSITLEKTTSNSSSIRTRPNSHHVAPETNNNNSTNGNSNNSSNGGFSFFKWKWGGNNSNGGSDDTKASQRDPNVSTSIITDNLNSYMFEEEISPGVVNNIIENNIWVGTDIRLFKIANFRKESFSFLEMTSSFFKKFKFINSDNDNYNNNEFDDNTQLRYTSRGLYR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.:*** *.:. ::.:* . : . * * : : . ::*. . :* : . .*.*: .* : ..:. .:: ... ::*. : * :* *: . ..**:: : **.: ** * .* * :**. : .::. .: . .: *. .. : : . : ::::*. :. * . . . * :: . :..: * *: * : .: * *:. .: : :* : :: . : : * .** . : . :: . : .:::. * :: : * * :*:: : .*:. :. . * .:: . *:...* :**:*:* .* :.:. * : : .* * :.: :*.: . : : ** : . *: : .:*:::.*:. :. * :* : *. .: : : . :* : :::* ..* .*: :**. :. :: **. .**:::::*:: : * : : :. : *. : : . :. .. * . . ***:* . . : ::.* : . . . : * * *: . ..: . . *: : **:: : : * *.* **. :: : : *.* . . * :.* :*:. * .: ** :: .::.* :* .*:::**:* .. ", "identical_positions": 111, "similar_positions": 275, "identity": "8.66%" }, { "cls_id": "homologset.agr.MGI:2445089", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZE49-1", "uniprot_id": "D3ZE49_RAT", "id": "D3ZE49-1", "name": "Trafficking protein particle complex subunit 12", "aln": "METAKDGEQSPS-EASPPTQAGPETISEPVPLEEEGQPLYHEETIDLGGDDFASEETEPTSEGSHNFGDKLNEHMMESVLISDSPNNSEGDVGDLGCLQDVGEPPRGATDHRLPDSTDKEVVDTLSNGSETDGDDTPRDISDMTPDSRASLKEDSTQEDVPAMPALENAGTEEVGPKDSLVPREEQTSEVSSSQSSSKDEPLPVCTIFSQATSTSSQPHLFLQDGFESQMVKSPSFSS-TSETSAKTPPPMVQPSPSLSTFFGDTMSSNSLASDFFDSFTTST-FISVSNPNAGSPVPEKLASLTAPVGEKSPDSTSPSYSTRMDRSESGVSRAALDVPESPKPFSQIQAVFAGSDDPFATALSMSEMDRRNDAWLPSQATREVLMSVATQQYGTVFIDKENLTMPGLKFDNIQGDAVKDLMLRFLGEKAAAKRQVLNASSVEQSFVGLKQLISCRNWRAAVDLCGRLLTAHGQGYGKSGLPTNHTTDSLQLWFVRLALLVKLGLFQNAEMEFEPFGNLDQPDLYYEYYPHVYPGRRGSMVPFSMRILHAELQQYLGNPQESLDRLHRVKTVCSKILANLEQGLAEDGGLSSVTQESRQASVQLWRSRLGRVLYSMANCLLLMKDYVLAVNAYLTVIKYYP----EQEPQLLSGIGRILLQQIGDIKTAEKYFQDVEKVTQ-KLDGLQGKIMVLMNRAFLYLGQNNFAEAHKFFTEILRMDPTNAVANNNAAVCLLYLGKLKDSLRQLEAMVQQDPRHYLHESVLFNLTTMYELESSRSMQKKQSLLEAVASKEGDS--FNTQCLKLA---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2L8-1", "uniprot_id": "TPC12_MOUSE", "id": "Q8K2L8-1", "name": "Trafficking protein particle complex subunit 12", "aln": "METAKDGEQSPS-EASPSAQAGPENIPEPMSREEESQPLYHEETIDLGGDEFASEENEPTSEGSHNFGDKLNEHMMESVLISDSPNNSEGDVGDLGCLQDVGEPPRGATDHRLPSSTDKEVVDTLSNGSETDGDDTPRDISDMTPDSRASLKEDSTQEDVTSMPALENAATEEVGPKDSLAPREEQTSEVSSNQSSSKDEPLPVCTIFSQATATPSQPHLFLQDGFESQMVKSPSFSS-TSETSAKTPPPMVQPSPSLSTFFGDTMSSNSLASDFFDSFTTST-FISVSNPNAGSPVPEKLSSLTAPVGEKSPDSTSPSYSTRMDRSESGVSRAPLDVPESPKPFSQIQAVFAGSDDPFATALSMSEMDRRNDAWLPSQATREVLMSVATQQYGTVFIDKENLTMPGLKFDNIQGDAVKDLMLRFLGEKAAAKRQVLNASSVEQSFVGLKQLISCRNWRAAVDLCGRLLTAHGQGYGKNGLPTSHTTDSLQLWFVRLALLVKLGLFQNAEMEFEPFGNLDQPDLYYEYYPHVYPGRRGSMVPFSMRILHAELQQYLGNPQESLDRLHRVKTVCSKILANLEQGLAEDGGLSSVTQESRQASVQLWRSRLGRVLYSMANCLLLMKDYVLAVDAYLTVIKYYP----EQEPQLLSGIGRILLQ-IGDIKTAEKYFQDVEKVTQ-KLDGLQGKIMVLMNRAFLYLGQNNFAEAHKFFTEILRMDPTNAVANNNAAVCLLYLGKLKDSLRQLEAMVQQDPRHYLHESVLFNLTTMYELESSRSMQKKQSLLEAVASKEGDS--FNTQCLKLA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVT3-1", "uniprot_id": "TPC12_HUMAN", "id": "Q8WVT3-1", "name": "Trafficking protein particle complex subunit 12", "aln": "MEDAGGGEETPAPEAPHPPQLAPP---------EEQGLLFQEETIDLGGDEFGSEENETASEGSSPLADKLNEHMMESVLISDSPN-SEGDAGDLGRVRDEAEP-GGEGDP------GPEPAGTPSPSGEADGDCAP---EDAAPSSGGAPRQD---------AAREVPGSEAARPE----------------QEPPVAEPVPVCTIFSQRAPPASG------DGFEPQMVKSPSFGG-ASEASARTPPQVVQPSPSLSTFFGDTAASHSLASDFFDSFTTSA-FISVSNPGAGSPAPASPPPLAVPGTEGRPE------PVAMRGPQAAAP------PASPEPFAHIQAVFAGSDDPFATALSMSEMDRRNDAWLPGEATRGVLRAVATQQRGAVFVDKENLTMPGLRFDNIQGDAVKDLMLRFLGEKAAAKRQVLNADSVEQSFVGLKQLISCRNWRAAVDLCGRLLTAHGQGYGKSGLLTSHTTDSLQLWFVRLALLVKLGLFQNAEMEFEPFGNLDQPDLYYEYYPHVYPGRRGSMVPFSMRILHAELQQYLGNPQESLDRLHKVKTVCSKILANLEQGLAEDGGMSSVTQEGRQASIRLWRSRLGRVMYSMANCLLLMKDYVLAVEAYHSVIKYYP----EQEPQLLSGIGRISLQ-IGDIKTAEKYFQDVEKVTQ-KLDGLQGKIMVLMNSAFLHLGQNNFAEAHRFFTEILRMDPRNAVANNNAAVCLLYLGKLKDSLRQLEAMVQQDPRHYLHESVLFNLTTMYELESSRSMQKKQALLEAVAGKEGDS--FNTQCLKLA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RE04-1", "uniprot_id": "F1RE04_DANRE", "id": "F1RE04-1", "name": "Trafficking protein particle complex subunit 12", "aln": "MDSSEGPAQRPITLDIDAGIETPETSVPP--QNDLTEASFREESIDLNAENFASPQDD--SIHSESLMDKLNDQMMESVMISDSPNSEEEDAVPIDSLLVLGQNDDEEASKTP----DGDAEEPNGDDSTEHEETSEGFLEEEKQEEKIIQADDDKREIAP--PNLETPESQDASIEIN-------------TISTPREDPVPVCTIFSQAAQPKTQALVP--DGFQPTLVKSPSFTTGSTETPNKLIPQVCQPSPSLSKFFTDNGAVN-PASDFFDSFTTSTSFISVSNPNAESLNPSESPQEAVPTST---------YFTPAANKPQGSP------VEVSAPMNKLQAVFSSGDDPFASALINSELDKRYDAWLPSDDTRKVLISVATQQISPGQIPREQLAMPGLKFDNLQGDAVKDLMQRFLGEQAAMKRQVLSANSVEQNFLGLKRLISTKNWRAAVDLTGRLLTAHGQGYGKSGQHTTHTTDSLQLWFVRLSLLMKLSLFQNAELELEPFGDLDHPNLYYEYYPAVYPGRRGSMVPFSMRLLHAELPQYLQKPQETLDRLHRIKSVCQKILSNLQEGLAEDGSMVNLTQENRLASLELWRSRLSRLMYSMANCLLMMKDYVLAVETYRSIIEFEP----EQKVQLLSGIGRIFLQ-IGDIRTAEKYFQDVENACQSKGKTATEETSVLMNRAFVYLSQNNYADAHTCFSSVLRLDPKNPVANNNAAVCLLYLGRLKESLGQLESLVHKDPALYLHESVLFNLTTMYELESSRSTQKKQALLEAAACREGDS--FNIQCLKLV---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPB6-1", "uniprot_id": "Q9VPB6_DROME", "id": "Q9VPB6-1", "name": "Trafficking protein particle complex subunit 12", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHKISEYFAN------DPPSFFDELASKPKGNNLSTEGSSSSASS-----------------------------------------TSSAPNMMSNTFVG---FFQPPEYVETPEAGEDSIKVGDDVRNLWELPRENEPG-------KLIMPGIHLQTDLADPISVAVTQHLGEAELSYRKILRVDDVTQDERGLRTLIHAGCYRTAVNLTGRLLTIYGQGYGRSGQPAKHSPHSLQLWFTRLALLAKLGEFELLNAEAEPFGQLTSPDVFYDFYPEMYNGKSGSIACFSFRLLLAELPIYLGKPHVALDRLSELHVTTREIKEHYLS-------------LHNKAAEEFWQRRCERVLHSIINCGLMMKKFSMIDDIMEGTLLKRSNLSKEDRRSLYSAWGRIYLQ-IGDIFGAEQKIAVSRRLRE---INSAPDLRDLVDKGLIAVAKNDFPEAYVIFQKALHLDTGNTMILNNMGVCLLYAGKLKDAINLYERAINLNPQKSLNESLLVNLSTLYELESNNSKAKKYNLLRLINRYKPDLNISIEICLKLQTIN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:* :* : ...***.:::.. .:*. .: * . . . :. .* . * .. . : *: .: .* : :: . :* ***::::. .*.:. : :.*** *::* ...* *. **: ** :*:**:* ***** :*****:.* :.*:..******.**:** **. *: : * ****:* *:::*::** :* *: **:. **:*:* *** ** :*: :**** .:: . :* : . . *: .:*: * *:::*: ** *:**.: : : : . *:. .* *. *** ** **** **: : .. : . *:: .:: :.:*::.:*: * . *::*. *.: ** .***** *:**::: * :: :* *:**:*.**:*:*****..* ** **. : * **** ", "identical_positions": 151, "similar_positions": 157, "identity": "18.62%" }, { "cls_id": "homologset.agr.MGI:2445092", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0H2-1", "uniprot_id": "A0A8I6A0H2_RAT", "id": "A0A8I6A0H2-1", "name": "", "aln": "-----------MARNVADLLALSQQEE---------------------LVDLPDSYPLSTSEDEGDSDGERKCQKLLEAVSSLGRTN--------------------------------------------KWKLAERSEAS-----------LMVSEFNVTSEGSGEK-----------------------------LVLSDLLGSAT---------------------------------ELSSLATVKKQLQRIKS--------KTLTIPLNKEVADRTLREAAFSKTSQMLSKWDPVVLKNRQAEQLVFPMEKELPAVAPIEHVFTG-WKARTPLEQEVFNLLHKNKQPVTDPLLTPMEKASLK---------AMSLEEAKIRRAELQRTRALQSYYEARARREKRIKSKKYHRVLKKGKAKKALKEFEQLWKDCPSAALQELEKMEKARMTERMSLKHQGKGKWAKSKAIVAKY-DLEARKAMQEQLAKNRELTQKLQVVSESEEDDEG--TEER-IVPVS--DGMDDLRMNADAVNPWMLSSCNSSAEGGDIKTDPEQIPEFVTHASSESEGDERPVAEELVLK-----ERSFQERVD-SNNAKPLDIQETEDSNSQEVLSESRILLQKLNK-ENHQSEDQEVSSVETVLHIQREDLAS--EKFLVLQRLERAHVLEQRGELGKEEHYPKKELSGPVLKG-----VWKEMNPPTHPDASGGKKKKEQMID----LQTLLTTPSPPVKSLAVPTVQELEDEVET-----DHKQLIKEAFAGDDVIREFLKEKREAIEANKPKDLDLSLPGWGEWVGMGL--KPSAKKRRRFLIKAP---ESSPRKDKNLPNVIINEKRNIHAAAYQVRAVPHPFTHHQQFERTIQNPIGYTWNTQRAFQKLTVPKVGTKLGHIIKPIKAENVGYHSSSRSDLSILQSNRKCLSRKQQKQLKK-SSAD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6EJB6-1", "uniprot_id": "UT14B_MOUSE", "id": "Q6EJB6-1", "name": "U3 small nucleolar RNA-associated protein 14 homolog B", "aln": "---------MNMARNVTDLLALSQQEE---------------------LVDLPENYPLSTSEDEGDSDGEGKRQKLLEAVSSLGRKN--------------------------------------------KWKLAERSEAS-----------RMVSEFNVTSEGSGEK-----------------------------LVLSDLLGSAT---------------------------------ALSSVAAVKKQLHRVKS--------KTLTPPLNKEEADRALREAAFSKTSQMLSRWDPVVLKNRQAEQLIFPMEKEPPAVAPIEHVFTD-WKVRTPLEQEVFNLLHKNKQPVTDPLLTPVETASIR---------AMSLEEAKIRRAELQRMRALQSYYEARARREKRIKSKKYHRALKKGKAKKALKEFEELWKDCPNAALQELEKMEKARMTERMSLKHQGSGKWAKSKAIMAKY-DPEARKAMQEQLAKNRELTQKLQVVSESEEEDGC--TEEG-IVSVS--HGMDDLQMNADGVNPWMLSSCNSNAKRGEIKTDPEQMPEFVAHVSSESEGDERPVAEELVLK-----ERSFQERVD-PNNAKLMDGQETEDSDSQEVL-------QKLNK-ESHQSDNQKVSSEENVLHIQREDLAS--EKLLVLQRLERAHVLEQQGELSKEEHYPKKGLSRPLLKG-----DWKEMKPLTNPDASGGKKKKEQMID----LRNLLTANSSPVRSLAVPTIQQLEDEVET-----DHKQLIREAFAGDDVIREFLKEKREAIETNKPKDLDLSLPGWGEWVGMGL--KPSAKKRRRFLIKAP---ESSPRKDKNLPNVIISEKRNIHAAAHQVRALPHPFTHQQQFERTIQNPIGYMWNTQRTFQKLTVPKVGTKLGHIIKPIKAENVGYCSSTRSDLSILQSSQKCLSRKQQKQLKKLSSAD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVJ6-1", "uniprot_id": "UT14A_HUMAN", "id": "Q9BVJ6-1", "name": "U3 small nucleolar RNA-associated protein 14 homolog A", "aln": "---------MTANRLAESLLALSQQEE---------------------LADLPKDYLLSESEDEGDNDGERKHQKLLEAISSLDGKN--------------------------------------------RRKLAERSEAS-----------LKVSEFNVSSEGSGEK-----------------------------LVLADLLEPVK---------------------------------TSSSLATVKKQLSRVKSK-------KTVELPLNKEEIERIHREVAFNKTAQVLSKWDPVVLKNRQAEQLVFPLEKEEPAIAPIEHVLSG-WKARTPLEQEIFNLLHKNKQPVTDPLLTPVEKASLR---------AMSLEEAKMRRAELQRARALQSYYEAKARREKKIKSKKYHKVVKKGKAKKALKEFEQLRKVNPAAALEELEKIEKARMMERMSLKHQNSGKWAKSKAIMAKY-DLEARQAMQEQLSKNKELTQKLQVASESEEEEGG--TEDVEELLVP--DVVNEVQMNADGPNPWMLRSCTSDTKEAATQEDPEQLPELEAHGVSESEGEERPVAEEEILLREFEERRSLRKRSELSQDAEPAGSQETKDSGSQEVLSELRVLSQKLK--ENHQSRKQKASSEGTIPQVQREEPAPEEEEPLLLQRPERVQTLEELEELGKEECFQNKELPRPVLEG-----QQSERTPNNRPDAPKEKKKKEQMID----LQNLLTTQSPSVKSLAVPTIEELEDEEER-----NHRQMIKEAFAGDDVIRDFLKEKREAVEASKPKDVDLTLPGWGEWGGVGL--KPSAKKRRRFLIKAP---EGPPRKDKNLPNVIINEKRNIHAAAHQVRVLPYPFTHHWQFERTIQTPIGSTWNTQRAFQKLTTPKVVTKPGHIINPIKAEDVGYRSSSRSDLSVIQRNPKRITTRHKKQLKK-CSVD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04500-1", "uniprot_id": "UTP14_YEAST", "id": "Q04500-1", "name": "U3 small nucleolar RNA-associated protein 14", "aln": "MAKKKSKSRSKSSRRVLDALQLAEREINGEFDNSSDNDKRHDARRNGTVVNLLKRSKGDTNSDEDDIDSESFEDEELNSDEALGSDDDYDILNSKFSQTIRDKKENANYQEEEDEGGYTSIDEEDLMPLSQVWDMDEKTAQSNGNDDEDASPQLKLQDTDISSESSSSEESESESEDDEEEEDPFDEISEDEEDIELNTITSKLIDETKSKAPKRLDTYGSGEANEYVLPSANAASGASGKLSLTDMMNVIDDRQVIENANLLKGKSSTYEVPLPQRIQQRHDRKAAYEISRQEVSKWNDIVQQNRRADHLIFPLNKPTEHNHASAFTRTQ-DVPQTELQEKVDQVLQESNLANPE-KDSKFEELSTA---------KMTPEEMRKRTTEMRLMRELMFREERKARRLKKIKSKTYRKIKK--------KELMKNRELAAVSSDEDNEDHDIARAKERMTLKHKTNSKWAKDMIKHGMTNDAETREEMEEMLRQGERLKAKMLDRNSDDEEDGR--VQTLSDVENEEKENIDSEALKSKLGKTGVMNMAFMKNGEAREREANKETLRQLRAVENGDDIKLFESDEEETNGENIQINKGRRIYTPGSLESNKDMNELNDHTRKENKVDESRSLENRLRAKNSGQSKNARTNAEGAIIVEEESDGEPLQDGQNNQQDEEAKDVNPWLANESDEEHTVKKQSSKVNVIDKDSSKNVKAMNKMEKAELKQKKKKKGKSND----DEDLLLTADDSTRLKIVDPYGGSDDEQGDNVFMFKQQDVIAEAFAGDDVVAEFQEEKKRVIDDEDDKEVDTTLPGWGEWAGAGS--KPKNKKRK-FIKKVKGVVNKDKRRDKNLQNVIINEKVNKKNLKYQSSAVPFPFENREQYERSLRMPIGQEWTSRASHQELIKPRIMTKPGQVIDPLKAPFK-----------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VUR2-1", "uniprot_id": "Q9VUR2_DROME", "id": "Q9VUR2-1", "name": "U3 small nucleolar RNA-associated protein 14 homolog A", "aln": "------------------------------------------------------------MSDDEEHYEPKAHKKLLQAIGSLGKVQ--------------------------------------------HIQKSTRDERQ-----------SLQDEFQLVKGVSSAETDHAPR----------------------AVGLNDLVDILR---------------------------------TSTKHSQTGKKLKNIHGSK------KVLQKPLEKPAADRIKRTIGYEGVTKKLGRWDAVVAQQRSAETQIFPLPSETVYVNTAANARPLNTRVKSNLAQELEANNRKLRELRKAQIGDTTDEKELAKQERLLLQKKLTRDELFARRKELAYLKMRESQKSAKARMQNKIKSKKFHKLQKRQKMLEQMKEFELLQKTDPEAALEKLNALEKSRVQERASLRHKNTGTWAKNLQIRAKY-DKDVRKDLAEQLAVSRELTQKKQVSDSEDETTKKRVLPEEEDNDYDPFNPWTKRKATEQTENGNGESEGSNWRQYWTKRNKNEKLLEEHRRDLEGVQDNDEQEEKETIRKPLIEVKPAKKKLKK--SKVKIENGWEVEDICPTDQKEAKASPNSKAIDDIFEKHEDHIRAKLNKKMEKLRERINKLKEVPVKGKKAKKKDVLQNLKSLALKKTKQQIEIDEPLNYEEDKN-SQNNIPAHVEGNTESTEIPAVDTIDPNKVTTLVFTQKKGNSGGFNDALIDDEAAEYDEEDAAAERQLTISQAFEDDDIVADFNRDKSKDSELKN-TELQLALPGWGSWAGAGISKEVMERRNKRLLLKLA---APEKRRDENKDNLYLNESASKQARQHMVSSIPFPFRSLADYEASIRAPVGRNFVPETAFRMLTRPAVITRKGQVIEPMTESELVK--PDRRLRHIVDRRIKRIPKVPPKAKIA-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*: : .: *:: :*. : . : . .: :: . *. : .*: :. . .. :.. .. ** : :* * .:. : :.:*: :* ::* *: :**: . . . . :: * ::: :: . : . :: :* * *: : . :** ::****.::: * **: : . :: :. : : :* ** :*:*: ...***. . * :.*: : * * ...*. * ...:* . . . . : : :: . . : . :* . . : . : .. : .: : . .. : : : .. . . :: : . . : : . * :: . * .:: * :** .**:: :* .:* . : .. .::: :*****.* * * : ::.: :: * *:*:* *: :.*. . : : :*.** ::* ::: *:* : .. :.: * * : *: *::*.*:. ", "identical_positions": 79, "similar_positions": 207, "identity": "8.21%" }, { "cls_id": "homologset.agr.MGI:2445094", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A1V7-1", "uniprot_id": "A0A8I6A1V7_RAT", "id": "A0A8I6A1V7-1", "name": "", "aln": "----------------------------MEPWRC----LPRDARPAALG---------FWGEPLAAC------SHNQQTTTFRHPVTGQFSSENSEYVLREEPHPHMSKQERNQRPSSMVSETSTAGTTSTLEAKPGPKIIKSSSKVHSFGKRDQAIRRNLNVPVVVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREEAVLGSIPLPSYVISPVAPEDRISRKYSFKAVHTGMRALIYS-TTTAGSQAEHSGMRTYYFSADTLEDMNAWVRAMNQAAQVLSRSSLKR--DKVERQAMPQANHTDACQECGHVGPGHSRDCPRRGYEDAIVFDRREQEEERFRSQRDTLEGRRDRSKARSPYLPAEEDALFVDLPGGPRGQQAQPQRAERNGLPP--YGLGEQNGTSGYSRTAPPRANLEKHSQRKTNLAQTEHWAKAQKGDGRSLP-LDQTLPRQGPSQPPS--FLENYQTLPRNTRYPSGSSSPP-PRNLPSDYKYAQDRASHLKMSS--EERRAHRDGTVWQLYEWQQRQQFRHGSPTAPIGAGSPEFTEQGRS-RSLLEVPRSISVPPSPSDIPPPGPP--RPFPPRRPHTPAERVTVKPPDQRRSVDISLGGSPRKARGHAVKNSSHVDRRSMPSMGYMTHTVSAPSLHGKSLEELSLLLTRLQRHQSKLASVRNFAVGQLLHHY--LTFPACQADDTYLQLKKDLEYLDLKIKNNEPLINVLYKVLKKSARGCRPGRSMTGRDLLKDRSLKPMKIAESDTDVKLSIFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQTEQYRDQPQHLEKITCQQRLLQEDLVHIRAELCRESTEMENAWNEYLKLEKDVEQLKQTLQEQHRR-AFFFQEKSQIQKDLWRIEDVMAGLSVNKENYRVLVGSVKNPERKTVPLFPHPSVPSLSPTESKPALQPSPPTSPVRTPLEVRLFPQLQTYVPYRPHPPQLRKVVSPLQSPTKATP--QAEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDREQGQCVNGDLKVELRSYVSEPELASFSGDVPRPSLGLVGSESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAENSSVTFSRPKSALERLYSGD--------HQRGKMSAEEQLERMKRHQKALVRERKRTLSQGER---TGLLSARYLSQPLPGDLGSWKREQEFDLQLLERAAQGD---------RKDKEEGWLKVQATPVMELDLEPQDYDLDINRELSKPEKVSIPERYVEVDPEEPPSVEELQARYQKAEKIRNILARSSMCNL-QPPGQDRNSLADLDTQMQEQERIINISYALASEASQRSKQVAVQPLA-------------LLPPKAPLSSRTVPPYPP-LSNGLHYTFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UIL6-1", "uniprot_id": "PKHA7_MOUSE", "id": "Q3UIL6-1", "name": "Pleckstrin homology domain-containing family A member 7", "aln": "-MAAAVGRDTLPEHWSYGVCRDGRVFFINDQLRCTTWLHPRTGEPVNSGHMIRSDLPRGWEEGFTEEGASFFIDHNQQTTTFRHPVTGQFSSENSEYVLREEPHPHMSKPERNQRPSSMVSETSTAGTTSTLEAKPGPKIVKSSSKVHSFGKRDQAIRRNLNVPVVVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREEAVLGSIPLPSYVISPVAPEDRISRKYSFKAVHTGMRALIYS-TTTAGSQMEHSGMRTYYFSADTLEDMNAWVRAMNQAAQVLSRSSLRRDVDKVERQAMPQANHTDACQECGHVGPGHSRDCPRRGYEDSYGFNRREQEEERFRAQRDPLEGRRDRSKARSPYLPAEEDALFVDLPGGPRGQQAQPQRAEKNGVPP--YGLGEQNGTNGYQRTAPPRANPEKHSQRKTGLAQAEHWTKAQKGDGRSLP-LDQTLPRQGPSQPLS--FPENYQSLPKSTRHLSGSSSPP-PRNLPSDYKYAQDRASHLKMSS--EERRAHRDGTVWQLYEWQQRQQFRHGSPTAPIGAGSPEFTEQGRS-RSLLEVPRSISVPPSPSDIPPPGPP--RPFPPRRPHTPAERVTVKPPEQRRSVDISLGGSPRKARGHAAKNSSHVDRRSMPSMGYMTHTVSAPSLHGKS------------------------------------------ADDTYLQLKKDLEYLDLK---------------------------MTGRDLLKDRSLKPMKIAESDIDVKLSIFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQTEQYRDQPQHLEKITCQQRLLQEDLVHIRAELCRESTEMENAWNEYLKLEKDVEQLKQTLQEQHRR-AFFFQEKSQIQKDLWRIEDVMAGLSANKENYRVLVGSVKNPERKTVPLFPHPSVPSLSPTESKPALQPSPPTSPVRTPLEVRLFPQLQTYVPYRPHPPQLRKVMSPLQSPTKAKP--QAEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDREQGQCVNGDLKVELRSYVSEPELASLSGDVPQPSLSLVGSESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAENSSATFSRPKSALERLYSGD--------HQRGKMSAEEQLERMKRHQKALVRERKRTLSQGEK---TGLLSARYLSQPLPGDLGSVC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IQ23-1", "uniprot_id": "PKHA7_HUMAN", "id": "Q6IQ23-1", "name": "Pleckstrin homology domain-containing family A member 7", "aln": "MAAATVGRDTLPEHWSYGVCRDGRVFFINDQLRCTTWLHPRTGEPVNSGHMIRSDLPRGWEEGFTEEGASYFIDHNQQTTAFRHPVTGQFSPENSEFILQEEPNPHMSKQDRNQRPSSMVSETSTAGTASTLEAKPGPKIIKSSSKVHSFGKRDQAIRRNPNVPVVVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREEAVLGSIPLPSYVISPVAPEDRISRKYSFKAVHTGMRALIYN-SSTAGSQAEQSGMRTYYFSADTQEDMNAWVRAMNQAAQVLSRSSLKRDMEKVERQAVPQANHTESCHECGRVGPGHTRDCPHRGHDDIVNFERQEQEGEQYRSQRDPLEGKRDRSKARSPYSPAEEDALFMDLPTGPRGQQAQPQRAEKNGMLPASYGPGEQNGTGGYQRAFPPRTNPEKHSQRKSNLAQVEHWARAQKGDSRSLP-LDQTLPRQGPGQSLS--FPENYQTLPKSTRHPSGGSSPP-PRNLPSDYKYAQDRASHLKMSS--EERRAHRDGTVWQLYEWQQRQQFRHGSPTAPICLGSPEFTDQGRS-RSMLEVPRSISVPPSPSDIPPPGPP--RVFPPRRPHTPAERVTVKPPDQRRSVDISLGDSPRRARGHAVKNSSHVDRRSMPSMGYMTHTVSAPSLHGKS------------------------------------------ADDTYLQLKKDLEYLDLK---------------------------MTGRDLLKDRSLKPVKIAESDTDVKLSIFCEQDRVLQDLEDKIRALKENKDQLESVLEVLHRQMEQYRDQPQHLEKIAYQQKLLQEDLVHIRAELSRESTEMENAWNEYLKLENDVEQLKQTLQEQHRR-AFFFQEKSQIQKDLWRIEDVTAGLSANKENFRILVESVKNPERKTVPLFPHPPVPSLSTSESKPPPQPSPPTSPVRTPLEVRLFPQLQTYVPYRPHPPQLRKVTSPLQSPTKAKP--KVEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDRELGQCVNGDSRVELRSYVSEPELATLSGDMAQPSLGLVGPESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAESSKATFPRPKSALERLYSGD--------HQRGKMSAEEQLERMKRHQKALVRERKRTLGQGER---TGLPSSRYLSRPLPGDLGSVC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TVT3-1", "uniprot_id": "A0AB32TVT3_DANRE", "id": "A0AB32TVT3-1", "name": "", "aln": "-MAAPLGRDTLPDHWSYGVCRDGRVFFINDKTRDTTWLHPRTGEPVNSGHMIRSDLPRGWEEGFTEEGASYFINHNQRSTTFRHPVTGHISSENTDFILQDQANLRMSKPPPEARPPSMVSESSVAISSSPADATSGSRNLKPSGKVHCFGKRDHSIKRNPNVPVVVRGWLYKQDSSGMRLWKRKWFVLSDYCLFYYKDSREETVLGSIPLPSYVISPVGPEDHISRKYAFKACHTGMRSYIYNKNSLIGSQAEHCGMRTYFFSADTQEDMNGWIRAMNQAALMQSHG-MKR---EAERSSKPEQHAVPQTNHFSSSKGSSQAESAQQTHIEVAELRPQRDGDECYVYSKDITEDPVKLMSPGEMEMEALSQSGAHSRP--PSTVPTQRNGLPSSGIPP------DQNGNVVYKRGLVPRTDTEKKVQRKTALAQVEHWVKVQKGDPKSHPTAEYTLPRRTPPLQPKSVMMDTYQSLPKTTRHHSGSSSPPVPRNLPSDYKYAHDRLSHFRMST--DERMATKEGMVWQLYEWQQRQQFRHGSPTAPIYTG-PDYMDTSAF-RVTLEMPRSISVPPSPCDMPPSGHPS-KSLSPRRPHTPADRVTVRPLDDFATVDTPILGSPRGICSQISKTS-QLERRSMPTMGYITHTVSAPSLHGKTPEELTLLLIQLRRHRAKLASVRSDTFTHLQNQHNGLSGPSLQADDTYIQLKKDLEYLDLKVGSCGSAFTFFLLPSSPS------LLKVTGRDSLKDRPPRPVKIAESDIDVKLSRLCEQDKILQELEARIRTLKEDKDKLESVLDVSHQQMEQYQDQPAHAEKIAYQQKLLREDVVHIRADISQVSTEMENAWSEYSHLERDVDRLRSALQDQMTHSALSQQEKSQMRKELWRIEDVLAGLSSSKANYRVIIDSVRNP-GESGPLPAITPMHWNTARERK--LVPSASLSAVPSLSDSPSMGELKAAQPSPHLSPVQPCTQQPLQLSHTALTPKWPEEDAPPRPPLPHLYSPDEHPPAVPPLPKETSVIRHTSVRGLKRQSDERKRDREIGQFSNGDHKVEIRAFLSEPELLVVGGQIGG-----LSRDSGYQTLPNRGLTSSSSRLNQSSNISSFVTLRRGLTTTSLKE---RPKSALERLYSGEP------VQQRGRMSAEEQLERMKRHQKALVRERKRTLSQGERQASTSRASSSSTSRPVSADLGSWRREQDFDLQLLERAVMGEERPVEHKERQRSHSDEWLTLSSTPMRELDLEPLDYQLDLSKELSKPQKVTIPERYVDMDPEEPLSPQEMEARHRKVERIKSILAKSSVQNIPPPAAVDKPVVPDIDSALQEQERIITMSYALASEASLKSKQVAASPPVNSPTSLPPPPPPPPLPPSAPVSVSAAPSAPPPLSNGIHYTFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B6RSP1-1", "uniprot_id": "PKHA7_DANRE", "id": "B6RSP1-1", "name": "Pleckstrin homology domain-containing family A member 7", "aln": "-MAAPLRRDTLPDNGSYGVCRDGRVFFIDDEARATTWLHPRTGQPVNSGHMIRSDLPSGWEEGFTKEGASFFIDHNQRTTTFIHPVTGQISTENSDFRLQDQPGGRMLKQ-----PSSTISEASTTVTTSTVDSTSGSKGSRSSGRVHSFGKRDHAIKRNPSVPVVVRGWLYKQDSSGMRLWKRKWFVLADFCLFYYKDSREESVLGSIPLPSYTIAPVGPEDHISRKYAFKAEHT--------------------GMRTYYFSADTQEDMNGWVRAMNQAALMQTHTVKRDECGHPDHVNVSEKLKKQAVPQTNHIN-SYVIPKPEVIQSDGLPEDKREGFVGEVEIQVTPREMEQARGKSPASRVVEVEVLAPGSTPPSRVASRAPSRAVSTPPVVQRNGTPIEQNGMPGCQRGATPSAQTPVQVQRRSTLEQVENWVKVQKEERHGLVSTESTVPRRTPPIHPKYGTMDKYQSLPKTSRQ----SPPAPHHQLPSEYKYSHDRLNHFQKIHGHTKRPTTHDNTVWQLFEWQQRQQFRHGSPSAPVYTPAPDYSTAVSSTRNNSDVSRSVSVPPTLADIPPPGPPGARLMSPRRPHTPAERVTVRPLEDRPIVEVPPSNSPHRLR---SYKSATIERRSMPPSAYITHTVSAPSLHGKT------------------------------------------ADDTYMHLKKDLEYLDLK---------------------------VSGTEALKGRPAKPVKVAESDVDVTLSRLCEQDKILQELEFRLSGLKDDKDKLESVLDVSHQQMEQYKDQPSHTDKIAYQQRLLQEDLVHIRADISRVSTEMERAWDDYSRMEQSVEQLRDVLQTQMTL-CTSPQEKNQLKRELWRIEDVMTGLSSTKETFKITVDSVKNPERKLVPSVIESTVPSR---------CMTPSAAEVRSP---------QRSLTSSPLP--LPLDNEDLRNRHPVPN--WEEDDAPPRPPLPLLYD-EDTPPVVPPLPKETSVIRHTSVRGLKRQSDERKRDRE-SSYSNGDYRLELRSYLSEPELPVSAHGADH-------VDPGYLTLQRRGLSGSSSRINQYGVAS--CSLRRDLELS----TMERPKSALERLCSGEPQLEQQSQPQRVRMSVEEQLERMKRHQRALVRERKRNLSQGER------HHSRASTRPVNSDPGSALFVEPY----------------------RPASDEWLTVRARPVMELELEPLDFEFDITRELSTPQKVWIPQRLIDDESDEDLSPEEKETRSRTVAKIKTLLSKSSMR------SSEQMDFSDLDLALQQQERIMSVPRALATEASIKRRQVTAKAMSEG----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * ** ..*. * * * :: .***::*:* *****::*.**::: *:::. :* * *.* :**:*.: ::*. ::..*.: :.*.:**.*****::*:** .*********:************:****:*:***********:**********.*:**.***:*****:*** ** *****:***** ****.*:******* : :: : . :: .: . . . .. : :. . * .. . . * : . : :*** .* * :: : **:: * *.*:*.:.** : :. : *:**: * . :.**:**:.:* *.*. ::***:***::** .*:: :* : ::. ****:*************:**: *:: * ::.**:****: .*:**.* * : :.********:****:* :: *: . .**: .* ::*****. .*:************: *****::*********** ::* : **.*. :*:*:**** **.** :****::**:** :: **::**:*****:* *:* ***:*** * :**: **:**:**:*****::.: *****.**.:* ::*..*::*:..** * . ***.*::::******* :*** .* .::: : **:** : * ..: :.. : * : : . . . *: . *::******** **. :: **.*****:*:::********************* .. *** ::*:*:::***** . :. * ** ***:.*:**::* . : :***.* ********* **: ** :**.***********:********.*.***: : ::*: .* ** ", "identical_positions": 441, "similar_positions": 268, "identity": "31.23%" }, { "cls_id": "homologset.agr.MGI:2445095", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK65-1", "uniprot_id": "LRC33_RAT", "id": "Q5BK65-1", "name": "Transforming growth factor beta activator LRRC33", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFLPLWLCLGFHFLIVEWRSGRGTATAASQGGCKVVDRVADCRSLN--------------------LASVPSGLPAHSRMLVLDANPLRVLWNHSLQAYPRLEDLSLHSCHLDRISHWAFHEQGHLQNLVLADNRLS--------------------ENYKESATALHTLLRLRRLDLS-----------------------------------------------------------------------GNSLTEDMAALMLQNLSSLEVVSLARNTLMRLDDSVFEGLERLVELDLQRNYIFEIEGGAFDGLTELRRLNLAYNNLPCIVDFSLTQLRFLNVSYNILEWFLAAR---EEAAFELEILDLSHNQLLFFP--LLPQCGKLHTLLLQDNSMG-----------FYRELYN-TSSPQEMVAQFLLVDGNVTNITTVSLWEEFSS----SDLSALRFLDMSQNQLRHLPDGFLKKTPSLSHLNLNQNCLTKLHIREHEPPGALTELDLSRNQLA--------------------------ELHLAPGLTGSLKNLRVFNLSSNQLLGVPTGLFHSASSITTLDMSHN------------------------------------------------------------QISLCPQTVPLDWEEPSSCVDFRNMASLRSLSLDGCGLKALQDCPFQG-TSLTHLDLSSNWGILNGSVSPLSAVAPTLQVLSLRNVGLGSGAAE-----------------------MDFSGFGNLRELDLSGNSLTSFP--KFKGSSALQTLDLRRNSLTALPQR-----------VVSEQPLRGLQTIYLSQNPYDCCGVEGWGALQ--HFKTIADLSMVTCNLSSKIIRVVELPEGIPQDCKWGQVDTGLFYLVLILPSCLTLLVASTVIFLTFKKPLL----------------------------------------QVIKSRCHWSSIY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BMT4-1", "uniprot_id": "LRC33_MOUSE", "id": "Q8BMT4-1", "name": "Transforming growth factor beta activator LRRC33", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEFPPLWLCLGFHFLIVEWRSGPGTATAASQGGCKVVDGVADCRGLN--------------------LASVPSSLPPHSRMLILDANPLKDLWNHSLQAYPRLENLSLHSCHLDRISHYAFREQGHLRNLVLADNRLS--------------------ENYKESAAALHTLLGLRRLDLS-----------------------------------------------------------------------GNSLTEDMAALMLQNLSSLEVVSLARNTLMRLDDSIFEGLEHLVELDLQRNYIFEIEGGAFDGLTELRRLNLAYNNLPCIVDFSLTQLRFLNVSYNILEWFLAAR---EEVAFELEILDLSHNQLLFFP--LLPQCGKLHTLLLQDNNMG-----------FYRELYN-TSSPQEMVAQFLLVDGNVTNITTVNLWEEFSS----SDLSALRFLDMSQNQFRHLPDGFLKKTPSLSHLNLNQNCLKMLHIREHEPPGALTELDLSHNQLA--------------------------ELHLAPGLTGSLRNLRVFNLSSNQLLGVPTGLFDNASSITTIDMSHN------------------------------------------------------------QISLCPQMVPVDWEGPPSCVDFRNMGSLRSLSLDGCGLKALQDCPFQG-TSLTHLDLSSNWGVLNGSISPLWAVAPTLQVLSLRDVGLGSGAAE-----------------------MDFSAFGNLRALDLSGNSLTSFP--KFKGSLALRTLDLRRNSLTALPQR-----------VVSEQPLRGLQTIYLSQNPYDCCGVEGWGALQQ-HFKTVADLSMVTCNLSSKIVRVVELPEGLPQGCKWEQVDTGLFYLVLILPSCLTLLVACTVVFLTFKKPLL----------------------------------------QVIKSRCHWSSIY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YC3-1", "uniprot_id": "LRC33_HUMAN", "id": "Q86YC3-1", "name": "Transforming growth factor beta activator LRRC33", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELLPLWLCLGFHFLTVGWRNRSGTATAASQGVCKLVGGAADCRGQS--------------------LASVPSSLPPHARMLTLDANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQEQGHLRSLVLGDNCLS--------------------ENYEETAAALHALPGLRRLDLS-----------------------------------------------------------------------GNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEGLERLRELDLQRNYIFEIEGGAFDGLAELRHLNLAFNNLPCIVDFGLTRLRVLNVSYNVLEWFLATG---GEAAFELETLDLSHNQLLFFP--LLPQYSKLRTLLLRDNNMG-----------FYRDLYN-TSSPREMVAQFLLVDGNVTNITTVSLWEEFSS----SDLADLRFLDMSQNQFQYLPDGFLRKMPSLSHLNLHQNCLMTLHIREHEPPGALTELDLSHNQLS--------------------------ELHLAPGLASCLGSLRLFNLSSNQLLGVPPGLFANARNITTLDMSHN------------------------------------------------------------QISLCPLPAASDRVGPPSCVDFRNMASLRSLSLEGCGLGALPDCPFQG-TSLTYLDLSSNWGVLNGSLAPLQDVAPMLQVLSLRNMGLHSSFMA-----------------------LDFSGFGNLRDLDLSGNCLTTFP--RFGGSLALETLDLRRNSLTALPQK-----------AVSEQLSRGLRTIYLSQNPYDCCGVDGWGALQ--HGQTVADWAMVTCNLSSKIIRVTELPGGVPRDCKWERLDLGLLYLVLILPSCLTLLVACTVIVLTFKKPLL----------------------------------------QVIKSRCHWSSVY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6AXL3-1", "uniprot_id": "LRC33_DANRE", "id": "Q6AXL3-1", "name": "Transforming growth factor beta activator LRRC33", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVCGCLSVVLSHAVVLLMLVLHSASGHPQTFP---CRLIQRVALCSGRQ--------------------LSVIPDCLPHETEEIFFDRNLLENLQDG-LSRYPFLRMFSCANNQLMTVAETAFIESHLLENLNLANNELH--------------------HGHKQVAQAFRSLTQLKTLDLS-----------------------------------------------------------------------GNGLSEDMVSVLVANLSSLESLYLSRNGMQRLDESTFRDLHQLKELNVERNLLFEISG-AFDHMKKLQRLNLAFNCLPCLVNFEMTQLLVLNASHNSIEWFITNQN--LTETFQLETLDLSDNHLLFFP--FLPTNNQIRTLLLSNNRVG-----------FYQHLANSTSSNWTTSVDYYNLGQNISNIT-MDLWNENLH----GNLSSVEFLDLSENKVNYFPQGFIKQMPQLYWLKLRSNCLQSFSLTSEDLPVTIYELDVSRNRLT--------------------------EIKASQTSKNKLNNLTHLNLSTNDLQNFPPMIFTSLPNLNTLDLSHN------------------------------------------------------------TVDVC---YSSNYMGLSGCVEWSSMASLKQLYLADCSIQNVPSSAFKG-TSLTHLELSNNP-NLHLKQQSLKGLANTLQHLGIGNTGLQD---------------------------FDFSPYTNLKSLNISRNSLSKLP--DSLMALNLKLLDLRDNSLTTIKSE-----------HAS-LLAKKLQTVYMNGNAFNCCHLDWFRTFGENKGIHVADLSEITCLDLNYRRHKVVLTDAVYCGFTNNNKESVVWYILLFVTVSVSIMGISVIYMLTFKPRMLP---------------------------------------RVIKKKCWRPTSY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KHN6-1", "uniprot_id": "Q0KHN6_DROME", "id": "Q0KHN6-1", "name": "Chaoptin", "aln": "MCRGRNLRTSAALVNLLAKCTKSTNGQAAVLAKDKESENRENLVPQKQRAQRQNKQQQHPQQYPQMMQQQQQQQQQQRQEQHQEQHNQRQQQGRQIEQMAMGTNAEAAAAKKHKHQTKPTDSECEGKHKHKRNRNNVAGVQQHVLRLKLELQLLLCALLPTALLLGLLPLPPGAAATAMISSAKGSVRELLLTEMGGGGVGVGVGGSSGGAAHPAGGGPGTGLAGGDGGGAAGIECPSFDNTACPCYKFEDGLFLECPGTTAISLRSTLERISAPIHSLSIYDFDRSVTSLSQDVFQPGVHIRHLQFSHSHLEALKDNSLRNVRSSLESLSIVNGKLTQMPSRALSSMQKLTALDFDYNEIVRVDDYSFYGLRISKLNMKGNRLQGMPEHAFAGLEECMQEIDVSENGLRTFPLMALRKLDHLRILRLSNNRIPTFYGDIQLATNNASAAAAAVGAFQLPSLIFLDLSSNQFAEIGPDCFRAFPQLKTLSFYANQIELVQPEAFKSLRELMSLDMSHNRIIGLDPKVFEKNKRLQTVDLSHNHIHTIGGVFSNLPQLREVFLSENNILELPADAFTNSTNVDVIYLESNAIAHIDPNVFSTLVNLDHLYLRSNFIPLLPVTLFDKSTKLTSLSLDNNEIQDLEIGMFRKLEHLREVRLHNNRIRRVRRGVFEPLPSLQELHIQKNSIEDIEPQAFHTLENMQHINLQDNQLTVLEDIFPDENSSLLSVQLEANYLHKVHPRTFSRQQKVQIMWLKDNQLTRVERSFFADTPQLGRLYLSDNKIRDIEKDTFVNLLLLQFLDLSGNQLRQLRRDYFAPLQDLEELSLARNHIEAIEGYAFAKLKNLKSLDLSHNPLVQLTRDIFSNEFPLNSLNLGNCSLRKLEQHAFKSLTNLNELNLERNQLNPADIQTLDIPNLRRLLLSHNNFSYAGSVGIMAGMLDRLRSLQQLSMSNCSLGQIPDLLFAKNTNLVRLDLCDNRLTQINRNIFSGLNVFKELRLCRNELSDFPHIALYNLSTLESLDLARNQLASIDFFKLSGTLNLRQLILRDNKITALSGFNAVNLTQLDSVDLSGNLLLSLPANFLRHSINLQKVHLSNNRFLQIPSSALSDVSIPRLSWLNLTGNPINRIYTVKEERYPYLKELYICQTNLSILTSKDFEAFQALQHLHLVNNRITRISPGAFKSLTNLLTLDLSVNELEMLPKERLQGLRLLRFLNISHNTLKDLEEFSVDLLEMQTLDLS-FNQLDRISKKTFRNLHGLLELFLMGNRMTVLSNDAFRFLRKLHVLDLRKNYFELVPLEPLRPLETNLRTLRLEENPLHCSCDAQKLWEWLRDHRKWSLSMGSGAGRGIGGLTGGLGGDSINYLRCEHPTELRGKVFGRMEPQQFCDAPLIPKMAIQDIQPYSVVVSWQSRDHLGLNGFEIVYHATGDGLVTAGSPTSRERDSLRDIHDPERQRTRDQARERSRERDRDRERDRERFSIATDEIHGKRLNGTASSTKLTKLSPNTRYHICVIGSGNWLSEPLANALQRLHTNESLREEEAVMMSAPLPESFSPYQHQHNRNSNGNANPAMVQDHNKKQNPDQDLDNVVGQDNALMEVLKNSHISACTDVQTLDSTPSLVTDENGLSSNGFIHSILTRRLGLIVGCCLGIIVFIVMISVLSYVKLKKKRIENAKRQAALPPEYISYRHFSIPNEELTRTAANAGTVAAAAAANNSHNSNNSTDEGSSPHMSSVPSGISAHISGTSLSTGGTGTGSTTTTATTPIGGVPLGKAGSTLVGVGLVVADSSVDVGYAHNHAHAHAHRHMAAGVVLNTNHLSVC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VV09-1", "uniprot_id": "Q9VV09_DROME", "id": "Q9VV09-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRTRRILEVIVILILAISSCDGSG---------------------GDIPLRCDEYDSMGYMDVN-------EAFCTVTGFTVTHSQNVVIKNIPPGNMVKFMKFYESTLLYMPFH----------------------------LFETFPYLKTLDVS------------------------------------------------------------------------NTNILELTRNAFSAASNLTYLNLAYNNLTSIQTSVFIGANVLMRLDLSYNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSIQPEVFRNMRRIKEVNLSNNRLIFIHPDTFADAASLENLVLS-----------------YNELKNFQLTEKNIVHQLHLDNNYLTNLT----------------INATRFVRASHN---QISELFLHQSLHIETLDLSANKLSSISNITN--ITHMLYLDVSDNPIG----------------------------PLNISTFSQLKRLRGLNLRGTGIRELKFGMFSKQKYLEELDLSFN-----------------------------------------------------------------------NLTILNLDMFVPYLTNLKKFLIDGNGLTELQGNRTFSEAFPQLQKLGVSRNRFNCSYLHHLLIPPSLPESVVLNIEPDTNLDET----------------------PHIRDVSCISQSQEVVNASFTAE--ESKLESQIQMLSKQLDIVGSHSKN---------------------LELHLAFMQIFAYVMGGLVLVGVVSLITLRYLKNQRSGRYDRSSIVFRSNATMEANLTLGSEDLQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : :. * : . : : : : . : . : : : : *: : :* * :: . . * : * * : : . * * .*.:. * : .:. ** : : :: * * * : : * : : .:: : *..*:* . :. .: * * . * : : ::: : . : *.* :. :: : : *.* * : : *::. * : . * * :.: : . :* . : :*:. * : . : .* .. : . : : .*. . . * : . .: : . * : *. : : .. . : : . . . . : ", "identical_positions": 40, "similar_positions": 127, "identity": "2.2%" }, { "cls_id": "homologset.agr.MGI:2445096", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLP0-1", "uniprot_id": "DHTK1_RAT", "id": "Q4KLP0-1", "name": "2-oxoadipate dehydrogenase complex component E1", "aln": "-MASATVAAAGRALRRAVPLLRRSYQTERGVYGYRPRK-AGSGEPRGDRARPSVDHGLARLVTVYCEHGHKAAQINPLFPGQALLDTVPEIQALVQTLQG--PFTTTGLLNMGKEEASLEEVLAYLNHIYCG-PISIETAQLQSQEEKDWFARRFEELKKETFTTEERKHLSKLLLESQEFDHFLATKFATVKRYGGEGAESMMGFFHELLKLSAYGGITDIIIGMPHRGRLNLLTGLLQLPPELMFRKMRGLSEFPENVAAIGDVLSHLTSSVDLDFGAHRPLHVTMLPNPSHLEAINPVAVGKTRGRQQSQEDGDYSPNGSAQPGDKVICLQVHGDASFCGQGIVLETFTLSNLPHFRIGGSIHLIVNNQLGYTTPAERGRSSLYSSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFFTNPVMYKIIRARKSIPDTYAEHLIASGLMTQEEVSDIKASYYAKLNGHLANVAHYSPPAPHLQARWQG-LVQPAACVTTWDTGVPLELLRFVGVKSVEVPEELQLHSHLLKMYVQSRMEKVKNGTNLDWATAETLALGSLLAQGFNVRLSGQDVGRGTFSQRHAMVVCQNTDDVYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGLVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDSDTVNMFVVHPTTPAQYFHLLRRQMMRNFRKPLIVASPKMLLRYPVAVSTLEEMAPGTAFKPVIGDSSVDPKNVKTLIFCSGKHFYALLKQRESLGAKKRDFAIIRLEELCPFPLDSLQQEMGKYKHVQDIIWSQEEPQNMGPWSFVYPRFEKQLACKLRLVSRPPLPAPAVGIGTVHQQQHEAILFKTFTS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ATU0-1", "uniprot_id": "DHTK1_MOUSE", "id": "A2ATU0-1", "name": "2-oxoadipate dehydrogenase complex component E1", "aln": "MASAATVAAAGRALRRAVLLLRRGYQTERGVYGYRPRK-AKSGEPRGDRARPSVDHGLARLVTVYCEHGHKAAQINPLFPGQALLDTVPEIQALVRTLQG--PFTTTGLLNLGKEAASLEEVLAYLNHIYCG-PISIETAQLQSQEERDWFARRFEELKKETFTTEERKYLSKLLLESQEFDHFLATKFATVKRYGGEGAESMMGFFHELLKLSAYGGITDIIIGMPHRGRLNLLTGLLQLPPELMFRKMRGLSEFPENVATIGDVLSHLTSSVDLDFGAHQPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSREDGDYSPNGSAQPGDKVICLQVHGDASFCGQGIVLETFTLSNLPHFRIGGSIHLIVNNQLGYTTPAERGRSSLYSSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIVDLLCYRQWGHNELDEPFFTNPVMYKIIRARKSIPDTYAEHLIASGLMTQEEVSDIKTSYYTKLNDHLANVAHYSPPATNLQARWQG-LVQPEACVTTWDTGVPLELLRFIGVKSVEVPEELQVHSHLLKMYVQSRMEKVKNGSGLDWATAETLALGSLLAQGFNVRLSGQDVGRGTFSQRHAMVVCQDTDDAYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPTLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGLVILLPHGYDGAGPEHSSCRIERFLQMCDSAEEGVDSDTVNMFVVHPTTPAQYFHLLRRQMIRNFRKPLIVASPKMLLRYPAAVSTLEEMAPGTAFKPVIGDSSVDPKNVKTLIFCSGKHFYALLKQRESLGTKKHDFAIIRLEELCPFPLDALQQEMSKYKHVRDVIWSQEEPQNMGPWSFVSPRFEKQLACRLRLVSRPPLPAPAVGIGTVHQQQHEDILSKTFTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96HY7-1", "uniprot_id": "DHTK1_HUMAN", "id": "Q96HY7-1", "name": "2-oxoadipate dehydrogenase complex component E1", "aln": "-MASATAAAARRGLGRALPLFWRGYQTERGVYGYRPRK-PESREPQGALERPPVDHGLARLVTVYCEHGHKAAKINPLFTGQALLENVPEIQALVQTLQG--PFHTAGLLNMGKEEASLEEVLVYLNQIYCG-QISIETSQLQSQDEKDWFAKRFEELQKETFTTEERKHLSKLMLESQEFDHFLATKFSTVKRYGGEGAESMMGFFHELLKMSAYSGITDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLTSSVDLYFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSPDNSAQPGDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFYTNPIMYKIIRARKSIPDTYAEHLIAGGLMTQEEVSEIKSSYYAKLNDHLNNMAHYRPPALNLQAHWQG-LAQPEAQITTWSTGVPLDLLRFVGMKSVEVPRELQMHSHLLKTHVQSRMEKMMDGIKLDWATAEALALGSLLAQGFNVRLSGQDVGRGTFSQRHAIVVCQETDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDGDTVNMFVVHPTTPAQYFHLLRRQMVRNFRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVIGDSSVDPKKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAIIRVEELCPFPLDSLQQEMSKYKHVKDHIWSQEEPQNMGPWSFVSPRFEKQLACKLRLVGRPPLPVPAVGIGTVHLHQHEDILAKTFA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5PRA2-1", "uniprot_id": "DHTK1_DANRE", "id": "Q5PRA2-1", "name": "2-oxoadipate dehydrogenase complex component E1", "aln": "-MLIHLPRLLHRSFGARRSFLASLYHTQRGVYGFRPRDGPERRAELTQISALNRDHGLARLVEAYRAHGHKVAKINPLLPQSPVLESVPEISLLNGAVRG--VLNTTGLRHFGKAEATAEEVVAYLESTYCG-GISVETSQLQTLEEREWFADRFEELKKEAFSPEERRMLAKLMLESQEFDHFLATKFATVKRYGGEGAESMMGFFYELFRSSVYSGVTDVVMGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPEHSPSIGDVLSHLTSTVELDFGAGHPLHVTMLPNPSHLEAINPVTQGKTRGRQQVKQDGDYSTDPHSRPGDKVICLQVHGDASFSGQGIVPETFTLSNLPHYRVGGSIHLIVNNQVGYTTPSERGRSSLYCSDVGKMVGCAIIHVNGDDAEEVLRATRLAVEYQRRFRKDVIVDLLCYRQWGHNELDEPFFTNPAMYKIIRSRKSIPDSYADQLISEGLMTDEERSQIKTSYYATLNNQLTNMTLYSPPPTNLQGRWGD-LVEPQNRVSCWDTGVAQPLLQFVGAKSVDIPEEIILHSHLRKTHVQARLQKLEEGTKLDWSTAEALAFGTLLCQGFNIRISGQDVGRGTFSQRHAMVVCQETNDMFIPLNHISSEQKGHLEVCNSALSEEAVLGFEYGMSIAQPRLLPIWEAQFGDFFNGAQIIFDTFLSGGEAKWLLQSGLVILLPHGYDGAGPEHSSCRIERFLQLCDSKEEGVDGDTVNMAVVNPTLPAQYFHLLRRQMIRNFRKPLIVASPKTLLRFSGAVSGLSDMGPGTSFKPIIGDSSVNPASVQRVLFCSGKHYYALLKHRETIPEAEKNTALVRVEELCPFPTEALQQELNKYTNAKEFIWSQEEPQNMGCWSFVSPRFEKQLACKLRLVSRPALPAPAVGIGTLHHQQHEAILTSSFS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA02-1", "uniprot_id": "DHTK1_DROME", "id": "Q9VA02-1", "name": "Probable 2-oxoadipate dehydrogenase complex component E1 homolog", "aln": "--MLRYLALSEAGIAKLPRPQSRCYHSEKGVWGYKPIAQREFQVAEDVRASRNSQANVYRFVEAFRQHGHKLAAVNPISIRTSQQE-LQELSPAFYGLQTQEPVRTDGLLSGPQVAHNVAQLEQLLKDIYCGRSTSAEFSYVEDIEEREWLARNFETLDQQQLGKSERCEIAELLIKSQAWDNFMALKFPTVKRYGGEGAESMLAFFWQLLRDSVQANIEHVVLAMPHRGRTPLQAALLNMRPAKVFRKLSGASEFSEDIEAMSDVISHFHVSEQLKILG-KKLSFSMVRNPSHLEAANPVAMGKTRSKQQARGEGAFG-DGSQPFGEHVLNVILHGDAAFAGQGINQECLNMAYVPHFEVGGSLHLIVNNQVGFTTPGDRGRSTAYTSDLAKSIQAPVFHVNGDDPEALARVTSLAFRYQREFRKDIFIDLNCFRRWGHNELDDPTFTNPLVYKIVHQRESVPDLYAQQLAKEQVLSESKAKEMRDEYMKYLGEELALAPAYQPPPSYFEKQWTNFQLAPSKELTYWDTGLDYSLLHYIGQQSVTFPEDFNIHPHLLKTHVNARLKKLENGVKIDWSTAEALAIGSLMYQGHNVRISGEDVGRGTFSHRHAMLVDQQTNEMFIPLNSMEGGNGGKLELAHSILSEEAVLGFEYGMAIDNPNNLIIWEAQFGDFANGAQIIIDTFIVSGETKWMESNALVMLLPHGYDGAASEHSSCRIERFLQLCDSKETSADGDSVNVHIVNPTTPAQYYHVLRRQLARNFRKPLVVVAPKTLLRLPAATSTHEDFQPGTLFHNVLGDTIAKPEQVRKVILCSGKHYYTLAEEREKR--QAYDTAILRLESLCPFPIQELQAQLAQYGNVQSFVWSQEEHRNMGAWTFVRPRFENLIGQQLHYCGRCEAPTPATGIGKVHKREVDEIVAAPFEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: *::::**:*::* : .: *:* .: **** * :**: . : : *:. :: . * ** : . :: *: *** * * : :: :*::*:* .** *.:: : .** :::*:::** :*:*:* **.*************:.** :*:: *. ..: .:::.****** * :.**:: * :***: * ***.*. : .**:**: : :* : . : * .:*: ******* ***: ****.:** : :* :. : *::*: : :****:*.**** * :.:: :**:.:***:*******:*:***.:****: * **:.* : ..::*****..* : *.* **..***.****:::** *:*:*******:* :*** :***:: *:*:** **::* ::::.: .::: .* *. .* . * **. :: :* . * :: *.**: **:::* :** .*.:: :*.** * :*::*::*: :* :**:***:**:*:*: **.*:*:**:********:***::* *:*:: :**** :. : * **:.:* *************:* .* * :******** ******:***: .**:**: ...:*:*********..:***********:*** * ..*.*:**: :*:** ****:*:****: *******:*.:** *** . *.* .:: *** *: ::**: ..* .*: :::*****:*:* :.**. : *::*:*.***** : ** :: :* :.:. :***** :*** *:** ****: :. :*: .* *.**.***.:* :: : *: .* ", "identical_positions": 386, "similar_positions": 289, "identity": "41.68%" } ]